PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_PSESM
Sequence: MSVELWQQCVELLRDELPAQQFNTWIRPLQVEAEGDELRVYAPNRFVLDWVNEKYLGRLLELLGERGQGMAPALSLLIGSKRSSAPRAAPNAPLAAAASQALSGNSVSSVSASAPAMAVPAPMVAAPVPVHNVATHDEPSRDSFDPMAGASSQQAPARAEQRTVQVEGALKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNPKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKADQAKVDLPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRDITIELIRESLKDLLALQDKLVSVDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDVFGGRDHTTVLHACRKINELKESDADIREDYKNLLRTLTT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_PSEU2
Sequence: MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEGKMNLSLREVGGGLLLVSQFTLAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTVAAGQFGADMQVHLINDGPVTFLFDT
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC1B_ARATH
Sequence: MSFSDSGSSSYGGEYKNFRQITRERLLCEMLRPERNGSSKLTWKVLVMDKFTVKIMSSACKMSEITQEGISLVEVITKHRQPMTAMEVIYFIQPTEENVTAFLSDMTGKSPLYKKAFVFFSSPVSRSLVNLIKKDMRAMKRIGGLKEMNLEYISMDIQGFVTNNENALEELFCDDENHQRADACLNVVAKRIATVLASLKEYPFVRYRGAKALDATTMTTYRELIPTKLAASVWNCLARYKQTIEDFPQTETCELLILDRSIDQIAPLIHEWTYDAMCHDLLNMEGNKYTHEVPSKTGDKPEKKEVLLDEEDSIWVELRDAHIADASERLHEKMTNFVSKNKAAQLKHSSKDFGDLSSKDLQKMVHALPQYSEQIDKLSLHVEIARTINRTIMEQGLRDLGQLEQDLVFGDAGRKDVIKFLSTNHIISHESKLRLIMIVAAIYPKKFEGEKGRKMMELAKLSGDDVVAVNNMRLLGPVHTECKKSTTGSFPLKFDVLKTKRAARRDRVGETQTWQLSRFYPIVEELVEKLSKGHLPKQDYPCMNEPKPTFYSGSLSPSASPVLPHSRRTPTWARRHLSDDGYFSDSVLGRASSGFKRKGQRIFVFIVGGATRSELRVCHKLTEKLDREVILGSSSFLDPLTFLTKMKQLNEEEEISLDDIVI
What is the function of this protein?
Involved in the vesicle trafficking.  Binds syntaxins (By similarity).
What are the official names of this protein?
Protein transport Sec1b, AtSec1b.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: ESYT1_MOUSE
Sequence: MEHSPEEGASPEPSGQPPATDSTRDGGSGVPPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGANPHLQTFTFTRVELGEKPLRIIGVKVHPSQRKDQILLDLNVSYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLTGDLPIVGAVSMFFIKRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPLQGGQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQWFQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVPGAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALSGQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHGDSPSEAPVGPLGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDLMDDRDKGGS
What is the function of this protein?
Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity).  Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels.  Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane (By similarity).
What are the official names of this protein?
Extended synaptotagmin-1, E-Syt1, Membrane-bound C2 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the extended synaptotagmin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Peripheral membrane protein. Note=Localizes primarily to the endoplasmic reticulum. Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels.
Protein: RPOB_STAAS
Sequence: MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGTCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ATPB_ACAM1
Sequence: MVDVHFSDEVPPLRHLLRAGPQAQIAIEGLTYLSANLIRGIALTPTQGLARGARVIDTGQSLQVPIGEHLLGRAFNVFGDPIDGLGPLKGMKRSLHGQAVPLHQRTTGTDILVTGIKAIDLLAPLERGSKAGLFGGAGVGKTVLITEMIHNIVSRYDGVSIFCGIGERSREGEELYREMKAAGVLNNTVMVFGQMNEPPGSRFRVGHAALTMAEYFRDQAHRDVLLMIDNVFRFIQAGSEVSGLMGQLPSRVGYQPTLATELAELEERICSTAHGAITSVQAVYIPADDLTDPAAVHTFSHLSASIVLSRKRTSEGLYPAVDPLQSGSKMLTPSVVGQRHYQVAQAVRKTLAEYEDLKDIIAMLGLEELAQNERQTVYRARRLERFLTQPFFTTEQFSGIPGKMVSLDQTLTGCEAILDDKCSGLSEQALYMIGAVDEAELEHQEREAQEVEEIGQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: G3P2_SYNY3
Sequence: MTRVAINGFGRIGRNFLRCWLGRTDSQLEVVGINDTSDPRTNAHLLRYDSMLGKLDADISADENSITVNGKTIKCVSDRNPLNLPWAEWNVDLVIEATGVFVTHEGATKHVQAGAKKVLITAPGKGPNIGTYVVGVNAHEYKHEEYEVISNASCTTNCLAPFGKVINDNFGIIKGTMTTTHSYTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVALVIPELQGKLNGIALRVPTPNVSVVDLVVQVEKNTIAEQVNGVLKEAANTSLKGVLEYTDLELVSSDFRGTDCSSTVDGSLTMVMGGDMVKVIAWYDNEWGYSQRVVDLAEIVAKNWK
What is the function of this protein?
Involved in photosynthetic carbon assimilation.  Catalyzes the NAD(P)-dependent oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG).  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.  It can use both NADP and NAD.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA1_MYCTO
Sequence: MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH
What is the function of this protein?
Involved in the persistence and virulence of M. tuberculosis.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.  It also catalyzes the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route).
What are the official names of this protein?
Isocitrate lyase 1, ICL1, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: RL32_XANCP
Sequence: MAVQKSRVTPSRRGQRRSHDALTAKQLSTDPTSGEIHLRHHITADGYYRGKKVITTKSSAVQED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ARGC_XYLFA
Sequence: MSTATFTLGIVGARGYTGAALITLLTAHPAIELIFVSSREYHGQPVAAHNPTYRGDLRFETLDPAAVAAKRADVVILALPNGNAAPYVHAIDATAPPTLIIDLSADTRFDPDWYYGLPELTRHTYTGQKRISNPGCYATAMQLAIAPLRDQLAGPPQCFGVSGYSGAGTTPSDKNNQALLRDNLMPYALTDHLHEREVSAQLGIPVEFMPHVAPHFRGITLTANLWLQRPLTREHIKILYATRYANDPLIDIIDPPPWVNQIAARHTVQIGAFTMALGNKRVVVVATLDNLLKGAATQALQNLNRALGLDELTAIPYHPKPPTSPLPSSPLAS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y455_METJA
Sequence: MKCSQCNKKLCYTGKDCKKDITQKIIEEYKKEENLKIAEVSAYIEATYYMKKTRLEEIIEFCKLMEYKKIGIAFCIGLENEAKILAKILSKHFEVYSVCCKVCGIDKDVFKFKKINKGEKEAMCNPIGQAEILNEIGTDLNIIVGLCIGHDILFQKYSKAPTTTFIVKDRVLSHNTAGAIYTKYYLKKLLEGK
What are the official names of this protein?
Uncharacterized protein MJ0455.
Protein: GL8D1_MOUSE
Sequence: MSFRKVNIIIWVLAVVLFLLVLHHNFLSLSSLLKNDISDSGIVGLQPIDFVASAHQHPVSERQEEIPVVIAASEDRLGGTIAAINSVHQNTRSNVMFYIVTFNSTADHLRSWLNSGSLKSIRYKIVNFDTKLLEGKVKQDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSASTKVIIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNVTNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYADVWEKWYIPDPTGKFSLIRRHMDTSNIK
What are the official names of this protein?
Glycosyltransferase 8 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: HUTU_BACCQ
Sequence: MEKVKQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYNAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALTVANEYKEKKEPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLTMQAKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVETAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_ECO27
Sequence: MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADILQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA1_EPIUN
Sequence: MLDESPMRKGDSVSNDQSNPESNASVSIHQQNQIITCVSPGPVCPNAIEIKRDIVIVRLRPVESCPGYRFFRRVFETLEKWQLQVDMFSTSLGRITLALGAAALQAGISDSCSARNDMMSRDLMHGMQKLLPDDHIELFPHMAIISVVGHPSRRMAGHIFATMDANDIPTVMISHDAARLGIACAISEQYTAKALCVFEQCLFRYSLTH
What is the function of this protein?
Aspartokinase-like protein; part of the gene cluster that mediates the biosynthesis of loline alkaloids, potent insecticidal agents composed of a pyrrolizidine ring system and an uncommon ether bridge linking carbons 2 and 7 (PubMed:15654104).  Lolines are structurally differentiated by the various modifications of the L-amino group and include norloline, loline, N-methylloline, N-acetylloline, N-acetylnorloline, and N-formylloline (PubMed:15861432, PubMed:25531527).  The first committed step is the condensation of O-acetyl-L-homoserine (derived from L-aspartic acid) and L-proline, probably catalyzed by the gamma-type pyridoxal 5'-phosphate(PLP)-dependent enzyme lolC, to give the diamino diacid, NACPP (PubMed:15861432, PubMed:16755627).  Ensuing cyclization, decarboxylation, and acetylation steps yield 1-exo-acetamidopyrrolizidine (AcAP)(PubMed:24374065).  LolO is required for installation of the ether bridge upon the pathway intermediate, 1-exo-acetamidopyrrolizidine (AcAP) (PubMed:29537853).  In sequential 2-oxoglutarate- and O(2)-consuming steps, lolO removes hydrogens from C2 and C7 of AcAP to form both carbon-oxygen bonds in N-acetylnorloline (NANL), the precursor to all other lolines (PubMed:24374065, PubMed:29537853).  The enzymes lolD, lolE, lolF and lolT have also been proposed to be involved in the ether-bridge installation (PubMed:15654104).  Further processing of the exocyclic moiety of NANL by fungal N-acetamidase (LolN), methyltransferase (LolM), and cytochrome P450 (LolP) enzymes, with occasional involvement of a plant acetyltransferase, generates the other known lolines (PubMed:25531527, PubMed:18655839).  LolN transforms NANL to norlonine which is monomethylated and dimethylated to respectively lonine and N-methyllonine (NML) by lolM (PubMed:25531527).  LolP catalyzes hydroxylation of the methyl group in N-methylloline (NML) and further oxygenation to N-formylloline (NFL) (PubMed:18655839).  A plant acetyltransferase is responsible for the acetylation of loline to form N-acetylloline (NAL) (PubMed:25531527).  LolA might interact with aspartate kinase to prevent feedback inhibition of its activity by these end products and thereby promote production of L-homoserine from L-aspartate (PubMed:15654104).
What are the official names of this protein?
Aspartate kinase-like protein lolA1, Loline biosynthesis cluster 1 protein A.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: Y1009_VIBPA
Sequence: MRLKTWIVAFFLGLFGTTVNADTTHKTDVSVTLSTAQGVQVLFVNGVSTDELSTPYTLIDGSNQVVIKVNKAIGRGDKRTQVYSAPYILGFSSGAGELYIDAPSFRDKRQADKLFEKDTMDWKVSINDKSIDYSQYKMPGKKGAFPYSNLDEQLAEYNELNGVYFSNGKRVELSELQATGTAKETHRVNSPLTKAKIAYLEMTDEERQLFMKWVSQQ
What are the official names of this protein?
UPF0319 protein VP1009.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: PFKA_STRPM
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_YERPN
Sequence: MTLLALGINHKTAPVSLRERVTFSPESMDQALNSLLQQPLVQGGVVLSTCNRTELYLSVEQQENLHEQLTAWLCNYHKLSPDDVRQSLYWHHGNDAVRHLMRVASGLDSQVLGEPQILGQVKKAFAESQRGQSLSSELERLFQKSFSVAKRVRTETEIGASAVSVAFAACSLARQIFESLSELHVLLVGAGETIELVARHLREHQVKHMIIANRTRERAQSLASEVGAEVITLPEIDARLADADIIISSTASPLPIIGKGMVERALKTRRNQPMLFIDIAVPRDIEPEVGKLSNAYLYSVDDLQAIIQHNMAQRQAAAVQAESIVQQESMNFMTWLRAQGAVETIRDYRSQAEQVRSEMTAKALVAIEQGANVEQVINELAYKLTNRLIHAPTKSLQQAASDGDMERLQLLRDSLGLDQH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RF1_THEVB
Sequence: MAEAYLLEKLRTVEQTFTELTRRLADPDVAVNPTEFQKVARSRAALEETVNAYHEWQSLNQQLVDARQLHKEAANEPELRQMAEEEIAHLSHRIAQLEERLKILLLPRDPNDEKNIMLEIRAGAGGDEAGIWAGDLVRMYSRYAKTQGWQVTLVSESLAEMGGFKEAILEIKGDRVYSKLKYESGVHRVQRVPATEASGRIHTSTATVAVMPEVDEVEVEIDPKDIELTTARSGGAGGQNVNKVETAVDLYHKPTGIRIFCTEERSQLKNKERAFQILRAKLYEIKLREQQEAITSMRRSQVGTGDRSEKIRTYNYKDDRVTDHRLGQNFSLSSVLEGDLEPIIQACISRDQQEQLAQLAAEQA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAR_STAAM
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIILEILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVSRLRKKLSEISMDSAIETKVGKGYMAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_ALBFT
Sequence: MPHNSYPLLHTINDPADLRLVPRAQLGALADELRAYLLHSVAKTGGHLSSNLGTVELTVALHYVFNTPHDRVVWDVGHQTYPHKILTGRRERMATLRQLGGLSGFPQRGESEYDDFGTAHSSTSISAALGMALAAKIRGEERYAIAVIGDGALTAGMAFEALNNAGVADCNLLVILNDNDMSISPPVGALNRHLAKLMSGQFYAAAKNVGKTVLKGAPPLFELAKRLEESAKGMVVPATLFEKFGFNYIGPIDGHDLDALIPTLENIKHLKGPQFLHVVTKKGQGYKLAEADPVAYHGPGKFDPAVGLQAPATSPKQTFTQVFGQWLCDMAAVDPRLVGITPAMREGSGMVEFEQRFPQRFFDVGIAEQHAVTFAAGLACEGLKPVVAIYSTFLQRGYDQLIHDVAIQNLPVVFALDRAGLVGADGATHAGAYDIPFLRCIPNVSVACPADENECRQLLSTAFAQNHPVAVRYPRGAGAGTVVQAGLEALPFGQGEIRRAGSSVAILAFGTLLHPALQVAEKLNVTVVNMRWVKPLDVALLLQVAADHDALVTVEEGAIMGGAGSAVLEALQAAGVLKPVLQLGLRDEFIEHGDPAKLLALQGLDAAGIQASITKRFAALLVPGRLALKAVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: EPPI_MACMU
Sequence: MGSSGLLSLLVLFILLVNVQGPGLTDWLFPRRCPTIREECEFRERDVCTRHRQCPDNKKCCVFSCGKKCLDLKQDVCEMPNETGPCLAFFIRWWYDKKNNTCSTFVHGGCQGNNNNFQSEANCLNTCKNKRFP
What is the function of this protein?
Serine protease inhibitor that plays an essential role in male reproduction and fertility.  Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility (By similarity).
What are the official names of this protein?
Eppin, Epididymal protease inhibitor, Serine protease inhibitor-like with Kunitz and WAP domains 1.
What are the subcellular locations of this protein?
Secreted. Note=Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
Protein: COAX_BURP0
Sequence: MCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVVRASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQLPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVPHTRHDTLVLTGLALIAHSA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.