PharMolix/UniProtQA huggingface dataset:
Protein: REG3A_RAT
Sequence: MLPRLSFNNVSWTLLYYLFIFQVRGEDSQKAVPSTRTSCPMGSKAYRSYCYTLVTTLKSWFQADLACQKRPSGHLVSILSGGEASFVSSLVTGRVNNNQDIWIWLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGNCGSLTATSEFLKWGDHHCDVELPFVCKFKQ
What is the function of this protein?
Acts as a hormone in response to different stimuli like anti-inflammatory signals, such as IL17A, or gut microbiome.  Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways.  Induced by IL17A in keratinocytes, regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.  In parallel, inhibits skin inflammation through the inhibition of inflammatory cytokines such as IL6 and TNF.  In pancreas, is able to permealize beta-cells membrane and stimulate their proliferation.
What are the official names of this protein?
Regenerating islet-derived protein 3-alpha, REG-3-alpha, Islet of Langerhans regenerating protein 3, REG 3, Lithostathine 3, Pancreatitis-associated protein 2, RegIII, Regenerating islet-derived protein III-alpha, Reg III-alpha.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA1_BURP1
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHADLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COPB_CANGA
Sequence: MTAEIDPPAYTLVFNPATNSTPNTVAEFQKALEKGSDETKIEAMKEILVTMLEGNPLPEMLMHIIRFVMPSKNKKLKKLLYFYWEIVPKLDQDGKLRHEMILVCNAIQHDLQHPNEFIRGNTLRFLTKLREPELLEQMVPSTLACLEYRHAYVRKYAILAVLSIYKVSEHLLPDAKEIINTFLLAETDPICKRNAFLGLSELDRDNALQYLQDNIDDIESLDPLLQAAFVQFIRKDAIQTPALKSQYCDLLLELLASATADEVVFETALALTILSGNQTVLIKAVSKMIDLAVKVSDNNVKIIVLDRIQDINERNPGCLEELTLDILRVLNAEDIDVRSKALTIAMDLVTSRNIEDVVQLLKKELQTTVINNEKEKSSDYRSLLIKTIRGIAVRFEEIAANIVSLLLDFITDLNSVAANGVIAFVKDVVELYPQLRSNILENLIAKLESVNSAKAYRGALWILGEYSTTESEIQDSWKHIRQSIGEIPILQTELKNQRKSQDEDDEATEESATKQAGPVILPDGTYATENAFGSSNNDNKKKLVENENRPPLRRFVLGGDFYTASILASTIVKLVLRFEKVSERAAVLNALKAEGLLMLVSIIRVGESSIVEKNIDEDSQERITTAIAILMDESNPDESSAERELLNIAFLDATKASFKGQFVAQKKTKLFKSSPVRKHKEAIDQSVSFRLLQENDNTAVSGDAIDEDLQLAIRGDAARDTSSIAISKLKKIVPLTGFSDPVYAEACITTNQFDVVLDVLLVNQTKETLKNFHVQFATLGDLKIVENPPATNVVPHGFHRVSVTVKVSSADTGVIFGNIIYDGGHGQDARYVILNDVHVDLMDYIKPAKTDDESFRTMWNAFEWENKISVKSKLPSLHAYLDELIKGTNMGVLTPVESLGEKDCRFLCCNLYARSSFGEDALANLCIELDPNTEQVVGYVRIRSKGQGLALSLGDRVALIAKQNNKVIVGHV
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta, Beta-coat protein, Beta-COP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: SGF29_CHICK
Sequence: MALVSADSRIAELLAELQRLLGHTQEERSRSEHNLINIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGIYSDAEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAMPAAGDYVAKPGDKVAARVKAVDGDEQWILAEVVSYSHAANKYEVDDIDEEGKERHTLSRRRVIPLPQWKANPETDPEALFQREQLVLALYPQTTCFYRALIHAPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKETKKK
What is the function of this protein?
Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (By similarity).  SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (By similarity).  In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (By similarity).  Also binds non-histone proteins that are methylated on Lys residues (By similarity).
What are the official names of this protein?
SAGA-associated factor 29, Coiled-coil domain-containing protein 101, SAGA complex-associated factor 29.
What is the protein family that this protein belongs to?
Belongs to the SGF29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CADH1_ARACO
Sequence: MGSLEAERKTTGWAARDPSGVLSPYTYTLRETGPEDVFIKIIYCGICHTDIHQIKNDLGASNYPMVPGHEVVGEVVEVGSDVTKFKVGDCVGDGTIVGCCKTCRPCKADVEQYCNKKIWSYNDVYTDGKPTQGGFSGHMVVDQKFVVKIPDGMAPEQAAPLLCAGVTVYSPLTHFGLKEISGLRGGILGLGGVGHMGVKLAKAMGHHVTVISSSDKKKEEAIDHLGADAYLVSSDATQMQEAADSLDYIIDTVPVFHPLEPYLSLLKLDGKLILMGVINTPLQFISPMVMLGRKAITGSFIGSMKETEEMLDFCNEKGITSTIEVVKMDYINTAFERLEKNDVRYRFVVDVAGSKLDQET
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 1, CAD 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: DUT_AZOC5
Sequence: MSATRLDVPVVRLPHGMDLPLPEYATAASAGMDLVAAVPAEVPLVIAPGAWALVPTGLALELPEGMEAQVRPRSGLALKFGVTVLNAPGTIDADYRGEVGVILINHGREPFTVSRGMRIAQMVIAGVQQITLVETGNLGETARGVGGFGSTGLDRTP
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: IASPP_MOUSE
Sequence: MDSEAFQHARDLLDLNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGAQAGVPSRMARYSTSPVPEHFGSRGSPQKIATDGIEARFGRSESAPSLHPYSPLSPKGRPSSPRTPIYLQPDTYSSLDRAPSPRPRAFDGAGSPHGRAPSPRPGIGPVRQPGPSTPFDYLGRAGSPRGSPLAEGPQAFFPERGPSPRPPAAAYDTAGTFGSPLLGAGGSAFTPPLRAQDDSTLRRRPPKAWNESDLDVAYEKKSSQTASYERLDVFTRPASPGLQLLPWRESSLDGLGASGKDHLTSATLPRNYKVSPLASDRRSDVGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRSTPRQRPIPLSMIFKLQNAFWEHGAGRAVLPGSPIFSRAPPPKLPPQPPPQPQMQPQPQPQPQMQPQSQAQPQTPAPQQTWSPMNEGLLKSPAELEPEPELEVLLAPVEEAGDADEGTVTRPLSPTRLQPALPPEAQTVPELEEVARVLAEIPRPLKRRGSMEQSPAVALPPTHKKQYQQIINRLFHRHGGPGPGGPEPELSTITEGSEARAGPPAPAPPAPIPPPAPPQSSPPEQPQSMEMRSVLRKVGSPRKARRARLNPLVLLLDAALTGELDVVQQAVKEMNDPSQPNEEGITALHNAICGANYPIVDFLIAAGANVNSPDSHGWTPLHCAASCNDTAICTALVQHGAAIFATTLSDGATAIEKCDPYREGYADCATYLADVEQSMGLMHNGVVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWASLHGQEGYVPRNYFGLFPRVKSQRSKI
What is the function of this protein?
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins.  Inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (By similarity).
What are the official names of this protein?
RelA-associated inhibitor, Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein.
What is the protein family that this protein belongs to?
Belongs to the iASPP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear.
Protein: MSHD_STRBB
Sequence: MLNEAAGARRIDVLDEVTPTMAEDVLRLVAEAARTDGQQAVSEQGRLQLRGRREGVRHLLLTEEPSGKLVGYAQLEDTDPVEAPAAELVVHPAHRGQGHGRALGVTLLRESGKRLRVWAHGGHSSARHLAQVLGLTLFRELRQMRRPLGPPATLDIPEPVLPEGVTVRTFRPGEDEAAWLAANAAAFAHHPEQGSLTLRDLEDRMGEPWFDPEGFFLAERGGEIVGFHWTKVHAQERLGEVYVVGVRPEAQGGGLGRSLTAIGLRHLAGRGLPTAMLYVDADNFPAVAVYGRQGFTTYETDLMYRTET
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: V1BR_HUMAN
Sequence: MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAETIIF
What is the function of this protein?
(Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, may recognize and internalize the complex formed by AVP/Arg-vasopressin, SARS-CoV-2 spike protein and secreted ACE2 through DNM2/dynamin 2-dependent endocytosis.
What are the official names of this protein?
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MX_SOLSE
Sequence: MTNLNEQYEEKVRPCIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKNDGEGWQGKISYQDHEEEIQDPADVEKKIEEAQIQIAGVGVGISENMISLEIASPDVPDLTLIDLPGITRVAVHGQPVNIGEQIKKLIHKFITKQETICLVVHACNVDLATTEALQMAQEEDPEGERTLGILTKPDLVDKGTEQMVIDILQNEVIHLKKGYMIVRCRGQQEIMQKVSLAEAIEREKAFFADHAHFCSLYDDGQATVPRLAEKLTLELVHHIEKSLPRLEEQIEEKLEQAQAELVRYGTGPPSDAAERLYFLIDKVTAFTQDTISLAAGEELRCGEKLNIFSALRREFDKWSIHLSHTGQKFNARIDKEVAIYEDKYRGRELPGFINYKTFEVMVKEQIKQLEEPAVKKLRDIADAVRKLFLQLAQCSFTGFPNLVKTAKAKIETIKLERESTAESMLRTQFKMEMIVYSQDRTYSNSLSDRKKEESEEEERRKGPKLHKERNCMDNHATLQELMLHLKSYYNIASQRLADQVPMVIRYQMLQESAVQLQRQMMQMMQDKENMEFLLKEDLNIGCKRATLQSRIKRLMKARAYLMEF
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx, Interferon-inducible Mx protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_AFIC5
Sequence: MPKRTLQGVVVSDKQDKTVVVRVDRRFTHPIYKKTIRRSKNYHAHDENNEFKAGDTVWIVESKPLSKLKRWTVVQSEKEKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL20_RHOBA
Sequence: MRTTKGAARRQSKKRLFKRAKGFRGGRGNLTRTVKETLLRSGAFAFRDRRVRKREFRKLWIIRINAAVKQHGLRYSEFIHGLNKAGIQLDRKSLSEMAIHDAAGFKQVCDKVKETLAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: COX1_DROMA
Sequence: PRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGALIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQLSYSPAILWALGFVFLFTVGGLTGVVLANSSVDIILHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLFTGLTLNNKWLKSHFIIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNVVSTIGSTISLLGILFFFYIIWESLVSQRQVIYPIQLNSSIEWYQNTPPAEHSYSELPLLTN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPOZ_SALPC
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL16_BACC4
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACDH2_MYCVP
Sequence: MRKVAIIGSGNIGTDLMIKVLRVSDLLEVAAMVGIDPDSDGLARARRLKVQTTHEGVEGLLALDEFDEIDIVFDATSAGAHIKNAETLRKFGKYLVDLTPAAIGPFVVPAVNLTDQLNRNVDNVNMVTCGGQATIPIVAAVSQVTPVAYAEIVASISSKSAGPGTRANIDEFTETTAQAIESVGGAARGKAIIILNPADPPVIMRDTVLCLTGDVDQDAVRDSVSTMVEEVSRYVPGYHLKQEVQFDRVSAADVRTLLPAGVGTVSTQISVFLEVEGAAHYLPAYAGNLDIMTSAALRVGEGIAERLNHAEAPRRSRA
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase [acetylating] 2.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RPOC2_EMIHU
Sequence: MQPDFKKIHSFENNLINKRSLKDLMYQAFLNYGIVKSSIIADRVKNLTFHFATQSGVSLSVEDLRVPAKKRELIGLTRNEVETTQKRYEIGSITSVEKFQKTIDIWNNANNFLKDDVLTYFRESDPLNPLYIMAFSGARGNISQVRQLVGMRGLMSNPQGQIIDLPIKSNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVAQDIIVRESDCGTTEGLWATELASNNFLNLRGRLLAEPIFTQEGNLFAPANTEITETFLQTLKTLKDHSPIKVRSSLTCTSTRSVCQNCYGWHLSHSKLVDLGEAVGIVAAQSIGEPGTQLTMRTFHTGGVFSGDLTRQVRSPMEGKIEYWEGHKASLFRTMHGKMGFRLKEEVNLIIKNSFGTTISFEIPAESLLLVNTDQYVYENEIIAEIQKDTNLILEEEQKEIYSETSGEVFFNALDVKVQADKQGNTYKTNNKAGLIWILQGSFYELPAFSETLLKPGLNLSKNTLLSRTPLYNKYPGWVQIDKSDNGTGICVQNFSVTLTNAFINEKVENSSRLQIKTDNQDFQFQLTTEPNSVLKQGDTIAVLDDNTYRTTTGGIVTYSLENPQASKKRKSVKNLFKGYFYWIPEETFKFSTLDEVRLSFSKNESIVGVGEEIMPNTFSKVGGFFQIKEAEQEVTIKPGELFELTSAESQIFDKSDRFVKPGNFIVPGKIITQQLVYLEFFELNEKQYILARPVQVFEVPKEEDLSLSQSFFPYNSHEHIKLKVIKRVFYKNWEKIISNNGINLLQTFIVFDFKQEQQGLEPRLEFTPSKVPGKSFLKIALYEVIKTFENNRKSSHSSLPTTTRNFVSNKQYVASNTLIGQIETTAGLVNKLAAINPHLNSGNMKEVLILNPSDLKKVFCPNVELLKKVSVGDLVRIGTLLNDNVKSPYSGQILEIFEDHILIRLSQPYLISAGTILHATSNNLVKAGDILATLVYETIKTTDIVQGLPKVEELLEARKVLHNALLAPCPGYAYVRFNKHGESTVQLIGLDNEVQTLALKPGIKTKFNSGDFVEVSSALTDGLISPHTKLETLFSYFKNRYTSFEACKLSFKLLQLFLIGEIQRTYRSQGVDIADKHVELIVKQMTSKVCIEDSGTTTFLPGEVLNFQKMADIALVAENKGEIPPSYVPLLLGITKASLNSDSFISAASFQETTRVLTEAAIEGRKDWLTGLKENVIIGRLIPAGTGFNYLENQERLAREKGEIDATFHREAKPLSENILDLRLVKKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TM10C_RAT
Sequence: MNVTVRFLRPFARYLVPYTFHRTRSNSYSRVLQRYVSSKVPSLPCHNKDSTSPPEQLELDGWKTTMKSSIQENGVSVVSDKDEDSLAATRELIEMWRLLGKEVPEHITEEELKTLMECASKSAKKKYLRYLYGKEMMKKAKQMKKEMKAAAREEAKRARSLEPSTGEEQRDFMFLRLWDRQTNIALGWKGVQAMQFGQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLEVDGAYHRELVKRYGEKWDKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRQNLATECLPLDKYLQWDVGNKNLTLDQMIRILLCLKNTGNWEEALKFVPRRKHTGYLEVPEHSQAAFRKLKKTKTLNSFRKGSLNVHMWKR
What is the function of this protein?
Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation.  Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends.  Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity.  The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; TRMT10C/MRPP1 acting as the catalytic N(1)-methyltransferase subunit.  The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme.  In addition to tRNA N(1)-methyltransferase activity, TRMT10C/MRPP1 also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
tRNA methyltransferase 10 homolog C, Mitochondrial ribonuclease P protein 1, Mitochondrial RNase P protein 1, RNA (guanine-9-)-methyltransferase domain-containing protein 1, mRNA methyladenosine-N(1)-methyltransferase, tRNA (adenine(9)-N(1))-methyltransferase, tRNA (guanine(9)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: GRCA_ECO8A
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: DXS_RHOP5
Sequence: MTEFSKTPLLDTIRTPDDLRKLRIDQVQQVADELRLETIDAVSVTGGHFGAGLGVVELTTAIHYVFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRTESDHDPFGAGHSSTSISAGLGMAVASDLAGTKNNVIAVIGDGSISAGMAYEAMNNAGAMNSRLIVILNDNNMSIAPPVGAMSAYLSRLYSGKTYRSLREAGKQIGKHLPKLIADRAARAEEYSRGFMMGGGTLFEELGFYYVGPIDGHNLDHLLPILQNVRDADAGPFLIHVVTQKGKGYAPAEAAADKYHAVVKFDIATGTQAKTKSNAPSYQNVFGASLVKEAQKDDKIVGITAAMPSGTGIDIFEKAFPKRTFDVGIAEQHAVTFAAGLATEGFKPFCAIYSTFLQRGYDQIVHDVAIQNLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNFVIMAASDEAELVHMVATQVAINDAPSAVRYPRGEGRGVEMPEVGIPLEIGKGRVVRQGNKIALLSFGTRLAECEKAADELATLGLSTTVADARFMKPLDVELVLKLAREHEVLITVEEGSIGGFGSHVMQTLAEHGMLDGEVRMRSLVLPDEFMDHDTPAVMYARAGLDAKGIVKKVFEALGKDKAETVKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GRCA_ECOK1
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: FLGH_PSEPK
Sequence: MNRLLSVFALGGAVLLAGCVAPTPKPNDPYYAPVLPRTPLPAAANNGSIYQAGFEQNLYSDRKAFRVGDIITITLNERTSASKNAGSQIAKTSKTDIGLTSLFGSTPNTNNPFGGGDLSLEAGYSGDRATKGDSKATQGNTLTGSITVTVAEVLPNGIIAVRGEKWLTLNTGEELVRIAGMVRADDIATDNTVPSTRVADARITYSGTGSFADASQPGWLDRFFISPLWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: EFTU_CHLAT
Sequence: MAREKFERKKPHVNIGTIGHVDHGKTTLTAAITMALAASTGAKGKRYDEIDAAPEERARGITINTAHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNVVVFLNKEDQVDDAELLELVELEVRETLSDYDFPGDEVPVVAGSALLALESLTQNPKIVKGENKWVDKIYSLMDQVDAYIPTPERDTDKPFLMAVEDVFSITGRGTVATGRVERGTVKVGEAIEIVGLREAPVTSIVTGLEMFQKTLEESVAGDNVGILLRGIQKKDIERGMVLAKPGTIKPHKSFEAQVYILNKEEGGRHTPFFQGYRPQFYVRTTDVTGKIESFQADDGSETQMVMPGDRIKMVVQLIQPIAIEKGMRFAIREGGRTVGAGVVFNILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.