PharMolix/UniProtQA huggingface dataset:
Protein: ASTB_PHOPR
Sequence: MKAREANFDGLVGPTHNYSGLSFGNVASEKNQANQSNPKQAAKQGLAKMKALADMGLVQGILAPQERPDVHTLRRLGFMGSDANVIEQAAKQAPKVLAACCSASSMWTANAATVSPSADTADGKVHFTPANLTNKFHRSIEHETTGRILQATFADKNHFAHHSALPAVEHFGDEGAANHTRFCHQYDEHGVEFFVYGRHAFDSRYPAPKKYPARHTFEACEAVVRLHQLTSDKVVIAQQNPDVIDQGVFHNDVIAVGNKNVLFCHEQAFLNQQAVYKELTAKVGGNFKIIEVPTSAITIEDAVTSYLFNSQLIEMPNGETLLILPEECRNNERVWAHVQTIINAKQGIDKVQIFDLKQSMANGGGPACLRLRVVLNEQELQAVNQSTLMNDTLFNRLNTWVDSHYRDTVTDADLADPQLVVESRAALDALTQILDLGSVYAFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: CWF19_SCHPO
Sequence: MEKEKLTNRTSTHKFNETDRETNHSRRHRHHHSRHRESKHGRHDRSERPSSREAGDRSRHERFSKEPLEVKKLPVENEYFDSKFASASSMPSSKDNPQNNDFTNSLQGLDFGTFGSRIQREPIDRKSNKPGEIFVGATLQNESSTSTEHKDIEQLETEINESGINYKIGDNGSRWRMMKLKRVFDMAQDQRRPVEEVALERYGSLKEFDFALEERDELELRKRTRKVQKEVPTGELYEKRCADEFKTRKDSGNGATYYKVIPDPSVNKDTPTESDLNRLKADLLRAQLKKDPNYESLEREYQKACDDFENSLHPSENSNSQATIPSKKRNFDDPTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKDKTYSNNLDYLDENAGKLSNRMKRGDVSLAQISSGGDLKKINHVLDTCPLCLNYETQPLAPVISLSHRAYVSLPTQPELAKYHCLIVPTGHRINTLSCDEDEWDEIRNFMKCIALMFDSMNLGVIFYENAPSPQRYMHTAIECIPVSKRILSLAPAYFREALSTSDEEWSQHRKIIDTLEGSKKYGKWAFRKMMVKELGYFHVWFSIDGGYGHVVEDEKAWGRHDQVPRQVFASMLNLPPEVIRRKGSWTGKKDPREDMFRSRFEKFDWTKGLID
What is the function of this protein?
Involved in mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor cwf19, Complexed with cdc5 protein 19.
What is the protein family that this protein belongs to?
Belongs to the CWF19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BL1S1_YEASZ
Sequence: MFLTFSMCVNWIIVKMPNRSEELDRLLDKIINSPHRTEASKTLQEIENNQSYILNVQLKKLLRLHDDSFKNKCVSPINYMLEKYTPYMGHTEALQKEAELVDRDLRILEMTYQLIEKNRNSK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: VIPR2_MOUSE
Sequence: MRASVVLTCYCWLLVRVSSIHPECRFHLEIQEEETKCAELLSSQTENQRACSGVWDNITCWRPADVGETVTVPCPKVFSNFYSRPGNISKNCTSDGWSETFPDFIDACGYNDPEDESKISFYILVKAIYTLGYSVSLMSLTTGSIIICLFRKLHCTRNYIHLNLFLSFMLRAISVLVKDSVLYSSSGLLRCHDQPASWVGCKLSLVFFQYCIMANFYWLLVEGLYLHTLLVAILPPSRCFLAYLLIGWGIPSVCIGAWTATRLSLEDTGCWDTNDHSIPWWVIRMPILISIVVNFALFISIVRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAAFPIGISSTYQILFELCVGSFQGLVVAVLYCFLNSEVQCELKRRWRGLCLTQAGSRDYRLHSWSMSRNGSESALQIHRGSRTQSFLQSETSVI
What is the function of this protein?
This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  Can be coupled to phospholipase C.
What are the official names of this protein?
Vasoactive intestinal polypeptide receptor 2, VIP-R-2, Pituitary adenylate cyclase-activating polypeptide type III receptor, PACAP type III receptor, PACAP-R-3, PACAP-R3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAX_SYNC1
Sequence: MLLVIDVGNTNTVVGLYEGQTLAYNWRITTDKGRTGDEYAMLLHELLRLAGVTFDRIEDVIVSSVVPPTLQAIESLCRKYVGRSPYVVGPGIKTGMPILYENPREVGADRIVNAVAAFARWQRSLIVVDFGTATTFDYINAKGQYHGGAIAPGLKISADALFDKASKLPRVEVSRPPTVVAKNTVNSIQAGLFYGYVGLVDGIVERMRKETRDDPLVVATGGLATLIADETQTIHEVESDLTLEGLRILYLRNKG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP8B_MOUSE
Sequence: MAARPGLLWLLGLALCVLGGGHLSHPPHVFPQRRLGVREPRDMQREIREVLGLPGRPRSRAPVGAAQQPASAPLFMLDLYRAMTDDSGGGTPQPHLDRADLIMSFVNIVERDRTLGYQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKEPSTHPLNTTLHISMFEVVQEHSNRESDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETEDGHSIDPGLAGLLGRQAPRSRQPFMVGFFRANQSPVRAPRTARPLKKKQLNQINQLPHSNKHLGILDDGHGSHGREVCRRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIIPKVCCVPTELSAISLLYYDRNNNVILRRERNMVVQACGCH
What is the function of this protein?
Induces cartilage and bone formation.  May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis.  Plays a role in calcium regulation and bone homeostasis (By similarity).  Involved in the generation of primordial germ cells; this function involves Bmp4 in a synergistic manner though separate receptor complexes seem to be involved.  Required for the initiation and maintenance of spermatogenesis.  Signaling protein involved in regulation of thermogenesis and energy balance.  Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.
What are the official names of this protein?
Bone morphogenetic protein 8B, BMP-8B.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PG079_VARV
Sequence: MSKVIKKRVETSPRPTASSDSLQTCAGVIEYAKSISKSNAKCIEYVTLNASQYANCSSISIKLTDSLSSQMTSTFIMLEGETKLYKNKSKQDRSDGYFLKIKVTAASPMLYQLLEAVYGNIKHKERIPNSLHSLLVETITEKTFKDESIFINKLNGAMVEYVSTGELSILRSIEGELESLSKRERQLAKAIITPVVFYRSGTETKITFALKKLIIDREVVANVIGLSGDSERVSMTENVEEDLARNLGLVDIDDEYDEDSDKEKPIFNV
What is the function of this protein?
Plays an essential role in viral DNA replication.  Binds to ssDNA with high affinity and localizes to cytoplasmic factories where nascent viral genomes accumulate.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.
What are the official names of this protein?
Protein OPG079, Protein I3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG079 family.
Protein: ATPH_DRANE
Sequence: MNPLVSAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ENO_ACIAD
Sequence: MFMSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTIIRDALVGKSVFEQKDIDNTMIELDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRGQTILTMPVPMMNIINGGSHADNNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLNKKGLNTAVGDEGGFAPNLRSNEEAITVILEAIGQTGYKAGSDIMLALDCASSEFYKNGQYILAGEGNKAFTSNQFSDYLAGLVNQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVTNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKDNGYSTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEELTKAAYRGKAEFKGLN
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL15_PECAS
Sequence: MRLNTLSPAEGAKHAPKRLGRGIGSGLGKTGGRGHKGQNSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAMITSEVRLSDLAKVEGDVVDLNTLKAANVIGIQIEFAKVILSGEVARPVTIRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: COX1_COPC7
Sequence: MTSTTQVLIALSSIVVAYFVKTALAKRKLNPRGLPYPPGPKGLPVIGNLTQLPQHKPWLVYKEWGRTYGDLMYLEAMGQPMIIINSLSRALDLLDKRAVNYSDRPHVPTMDLCVLMKLDWVFAFMQYGADWRNHRRAFHQYLNHNMVHNYHPIQEQETQEFLRALIARPKDFLAHTRHLFGSIIIRISYGFEDEEYNKVLVEEAEALASGFSESIIPGRYLVNAFPFLRHVPSWLPGAGFQRTMQYLRKISEKTLSEPFDNVKEALKTGNRQVGPSLAVGLIESLPDETHANRTSLEVVARNTSALSYIAGADTTVSSAQALILALAMHPEVQRKAQKEIDSVVGTDRLPNMSDKPNMPYVQAIVKEAGRWHTVLPLGFIHVSAKEDEYDGYFIPKGSFIFVNTWAIMHDPDVFKNPLQFNPERYLKNGQIDTSVLDPEAATFGFGRRICPGRWLSNDSLFLMAASLLATFNIAAPKDRTGKPIPLSLDTSSHLITAPLPYDCEFQLRSPKYAALLQK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of alpha-cuprenene and oxidized derivatives (PubMed:19400802).  The alpha-cuprenene synthase COP6 is the only sesquiterpene synthase identified in C. cinereus that appears to be part of a biosynthetic gene cluster and is highly specific since it catalyzes the cyclization of (2E,6E)-farnesyl diphosphate into only one product, alpha-cuprenene (PubMed:19400802, PubMed:20419721).  The cytochrome P450 monooxygenase COX2 then oxidizes the cyclohexadiene ring of alpha-cuprenene at positions 1 and 4, yielding first alpha-cuparene, followed by alpha-cuparophenol and a further yet unidentified compound resulting from one additional oxidation step (PubMed:19400802).  The cytochrome P450 monooxygenase COX1 then likely catalyzes the oxidation at position 9 of the pentane ring of alpha-cuprenene to give the corresponding hydroxy or ketone derivatives (PubMed:19400802).
What are the official names of this protein?
Cytochrome P450 monooxygenase COX1, Alpha-cuprenene oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL5A_XENLA
Sequence: MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGIKVGLTNYAAAYCTGLLLARRLLNKFGLDKVYEGQVEVTGDEYNVESIDGEPGAFTCYLDAGLTRTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNPEVHRKHIFAQNVAEYMRLLMEEDEDAYKKQFSQYIKNGVTADQVEDLYKKAHAGIRENPVHEKKPKKEVKKKRWNRAKLSLEQKKDRVAQKKASFLRAQEKADS
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.
What are the official names of this protein?
60S ribosomal protein L5-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: VIRG_HYPVG
Sequence: MAPPKFSITPEKEASRSQWIHRQLIAKTPPVAKDVNLSGQTAIVTGSNTGLGLETARQLLYLGLSKLILAVRSEEKGKAAREELLADKEAGSGEIEVWNLDLESYDSVIQFADRAKALDRLDIAILNAGLFQAKETFIASTGYERCVQVNYLSSVLLMTLLLGALKSKNETRPGRLVLVSSDTAAWANFKEQKSRPILATFKNKADKWDMQERYGVSKLLGQFYLTELAKRVPASVVTIDAANPSFCYGTALTRDGDGTIAGLLLNGFRRVVGKPTAVGALSIVHAAVSFGEEVHGQYAEDGEIRPMAPIIYKPEAEEIGKQLWDETLAELSFARLEESIQELTS
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of virensols and trichoxide, fungal natural products that contain or are derived from a salicylaldehyde core (PubMed:31790246).  The pathway begins with the synthesis of the reduced chain in virensol C by the highly reducing polyketide synthase virA via condensation of one acetate and 8 malonate units (PubMed:31790246).  VirA has interesting programming rules since the first 2 ketides are fully reduced, the 3 following ketides undergo beta-dehydration, and the last 3 ketides are only reduced to beta-hydroxys to yield the trihydroxy portion (PubMed:31790246).  The production of aldehyde virensol C by virA alone is surprising, since virA does not contain a reductase (R) domain that is typically associated with reductive product release in HRPKS (PubMed:31790246).  The cupin-domain enzyme virC is involved in enhancing virA product turnover (PubMed:31790246).  The short-chain dehydrogenase virB then oxidizes the C-7 alcohol of virensol C to a ketone, yielding virensol D (PubMed:31790246).  Virensol D is further transformed to salicylaldehyde 5-deoxyaurocitrin by the short-chain dehydrogenase virD (PubMed:31790246).  VirD catalyzes the dehydrogenation of C-3 to form the beta-ketone aldehyde, which is followed by the generation of the nucleophilic C-2 that is required for the intramolecular aldol condensation between C-2 and C-7, itself followed by dehydration and aromatization which leads to salicylaldehyde 5-deoxyaurocitrin (PubMed:31790246).  While the dehydrogenation of virensol D is definitely catalyzed by virD, the aldol condensation and dehydration may be uncatalyzed or assisted by virD (PubMed:31790246).  The short chain dehydrogenase virG then converts salicylaldehyde 5-deoxyaurocitrin into virensol B which is further hydroxylated by the cytochrome P450 monooxygenase virE to yield the hydroquinone virensol A (PubMed:31790246).  VirI then may oxidize virensol A to form the quinone, while virH performs the epoxidation (PubMed:31790246).  Finally, the two remaining short-chain dehydrogenases, virK and virL, are probably responsible for reducing the ketones to the corresponding alcohols to furnish the epoxycyclohexanol structure in trichoxide (PubMed:31790246).
What are the official names of this protein?
Short chain dehydrogenase virG, Trichoxide biosynthesis protein virG, Virensol biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS8_ALIB4
Sequence: MMNDIIADALTRIRNAAMRRLEVATLLHSNTVVGVLNVLLQKEYIAGFKVIDGQNNKKTIQVELKYDDNEKSVINEITRVSKPGRRVYKSASEIKNFKNGYGTIIVSTNKGVIANDEAYAANVGGEVLCTVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: EFG_XANP2
Sequence: MPRTHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMTQEQERGITITSAATTAIWAGKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYNVPRIVFVNKMDKIGADFYRCVEMIVDRVAGNPVCCQLPIGSENNFKGVIDLVRMKAVVWEDEALGAKYHDEEIPADLADKAAEYRNKLVEAAVELDDDAMTAYLDGVEPDVATLKSLIRKAVIGRKFNPVFCGSAFKNKGVQPLLDAVVDFLPSPIDRGAIKGIDFKTEEDTVRMPSDDEPTSVLAFKIMDDPFVGTITFCRVYAGKMETGMGLLNSTRDKRERVGRMLLMHANNREDIKEAYAGDIVALAGLKDVRTGDTLCDPAKAVILEKMEFPEPVIEIAIEPKSKADQEKLGIALSKLAAEDPSFRVSTDFESGQTILKGMGELHLDIKVDILKRTYKVDANIGAPQVAYRETITKKYEVDYTHKKQTGGTGQFARVKFIVEPNEVGKGFVFESAIVGGAVPKEYIPGVQKGLESVLGAGVLAGFPVVDVKVQLIDGAFHEVDSSALAFEIASRAAFREALQKGSPVLLEPIMKVEVVTPEDYTGSVIGDLNSRRGQIQGQDMRGNANVVNAMVPLANMFGYVNTLRSFSQGRATFTMQFDHYEQVPSNVAQEVQAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP_NEOFI
Sequence: MRGLLLAGALALPASVFAHPAHQSYGLNRRTVDLNAFRLKSLAKYVNATETVIEAPSSFAPFKQQSYVEAATQHVKMIAPDATFRVVDDHYVGDNGVAHVHFRQTANGLDIDNADFNVNVGKDGKVFSYGNSFYTGQIPSSAALTKRDFSDPVTALKGTTNTLQLPITVDSASSESTEGKESYVFKGVSGTVSDPKANLVYFVKDDGTLALTWRVETDIDSNWLLTYIDAKSGEQIHGVVDYVAEADYQVYAWGINDPTEGERTVVKDPWDSAASEFTWISDGSTKYTTSRGNNGIAQSNPNGGSSYLNNYRPSSSSLSFKYPYSPSSSPPSSYIDASIIQLFYTANTYHDLLYTLGFNEKAGNFEYNTNGQGGRGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYVWTESTPYRDGSFEAGIVIHEYTHGLSTRLTGGPANSNCLNALESGGMGEGWGDFMATAIRLKPGDKRSTDYTMGEWAANRPGGIRQYPYSTSMSTNPLTYTSVNSLNAVHAIGTVWATMLYEVMWNLIDKHGKNDAPKPTLRDGVPTDGKYLAMKLVIDGMALQPCNPNFVQARDAILDADTALTGGENQCEIWKAFAKRGLGAGAQYSSRNRVGSTEVPSGVC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase MEP, Elastinolytic metalloproteinase MEP, Fungalysin MEP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTLD_ECOBW
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGQVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: CMOB_HAMD5
Sequence: MTEFSHFYQWIVNNPFEIWLNTLPSQLTAWRLSVLKNPKAKAWLNTVQGLPELLPSYLNLLDRIQADISPPISESLQKGIENRLKALMPWRKGPFSLYGIHIDSEWRSNCKWKRILPHLDSLVGKKVLDVGCANGYHLWRMLGAGARLAIGVEPMPLFFFQFMAVKKLLGEALKAQILPLRIENIAPVEAFDTVFSMGVLYHRRSPLDHLYQLKNQLRSSGQLVLETLVIDGNDQQVLIPEKEYAKMRNVYFIPSVSLLNVFLKKCGFIDVRLVDVTATSTDEQRRTCWMTSESLLDFLDPEDHSKTIEGYPAPFRAILTAYKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: GAG_MLVDU
Sequence: MGQTVTTPLSLTLDHWKDVQCIASNQSVDVKRRRWVTFCSVEWPSFDVGWPLDGTFNLDIILQVKSKVTCPGPHGHPDQVPYIVTWEALVYHPPPWVKPFVSPKPFPLSTLPFSPPGPSAHPPSRSDLYTALIPSKPPKSRVLPPNGGPLIDLLTENLPNLPPLSKGPVKKRRPPPPRYSPPNPMESRVRGRRDPPAADSTSSQAFPLRMGGDGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWNYSTPEGRNHLVLYRQLLLAGLHNAGRSPTNLAKVKRITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRRETEEKEERRRAEDEQREKERDRRRHREMSKFLATVVTGQRQDRQGGERRRPQLDEDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLGD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion.
Protein: URE1_PROM1
Sequence: MPFKISRQAYAETYGPTKGDRIRLADTDLILEVEQDHTHYGDEVKFGGGKVIRDGMGQSQQSRDNGVVDTVITNALILDWWGIVKADIGIKDGKISGIGKAGNPDTQEGVNIIVGASTEAIAGEGSIITAGAIDSHIHFICPQQIETALASGVTTMLGGGTGPATGTNATTCTPGAFHISRMLQSAEGFPVNLGFFGKGNATNKAALEEQVRAGACGLKLHEDWGTTPACIDSCLSVADQLDVQVCIHTDTLNEAGFVEDTIKAIKGRTIHTFHTEGAGGGHAPDIIKICGESNVIPSSTNPTRPFTLNTLEEHLDMLMVCHHLDPKIPEDVAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVISRTFQTAHKMKVQRGALPEDNQRNDNHRLKRYISKVTINPAIAHGISAHVGSVEVGKLADLVLWKPGFFGIKPDLVVKGGCIAWAQMGDANASIPTPQPVHGRPMFSSFGKAISPTCLTFLSENAIDAGVPERLKLERTCAPVKDTRKISKQSMKLNDARPKIEVDPQTYEVFANGELLTCEPAESLPLAQRYLLL
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_RHOPB
Sequence: MTDILDELDAGRAPLAPTLADLRGDWARAEPSAHLQRLESESIHILREVAAEFAKPVMLYSIGKDSSVLLHLAMKAFAPGKPPFPLLHVDTTWKFREMIEFRDQRMRELGLDLIVHINPDGVAQGIGPFSHGSALHTDVMKTQGLRQALEAHGFDAAIGGARRDEEKSRAKERIFSHRSAAHRWDPKNQRPELWSLYNTLLAPGESMRVFPLSNWTERDVWDYILVEQIPIVPLYFAALRPVVERDGALIMVDDARMPLRPGEVPQLRSVRFRTLGCYPLTGAMPSTATTLEQIVDEMLASRSSERQGRVIDRDSTGSMERKKAEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: SYT_SALTY
Sequence: MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDATLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHDARETFVKRGETYKVAILDENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQIRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDVIEKLQQEIRSRSLQQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.