PharMolix/UniProtQA huggingface dataset:
Protein: SYM_CLOPE
Sequence: MCKKPYYITTPIYYPSTNLHIGNTYTTVAADAIARFKRLTGHEVMFLTGTDEHGQKIERIANEKGITPKEHVDEIVAGIKDLWKMMNISYDKFIRTTDDYHVKAVQEIFKKLYDQGDIYKDSYEGLYCTPCESFWTETQLVNGNCPDCGRPVEKAKEEAYFFKMSKYADRLIQYIEEHPDFIQPESRKNEMLNNFLRPGLQDLCVSRTSFTWGIPVSFDEKHVIYVWIDALSNYITALGYGQENQELYKKFWPADVHLIGKDILRFHTIYWPIMLMALGLELPKQVFGHGWLLVDGGKMSKSKGNVVDPVVLVNMFGADAVRYYLLREIPFGSDGLFNNEIFIKKVNTDLANDLGNLLSRTIAMVYKYFGGVIQAPTCKEPIDDELINLALSTPGKVEASIDALKIPEALESIWTLISRANKYIDETTPWILAKDEEKKERLGTVLYNLLETLRFVSVMISPFLTETSVKINAQLNTKVTTWESLKEFNGTVAGDKVVKGDVIFPRIDVEEKLAELEALKPAPVKPANEELVENPIKEEITIDDFDKIDLRVVKVLECEPVKKAKKLLKLKVDLGGEERQVISGIAQYYKPEELVGKYVVLVANLKPVKLRGELSQGMILAAAPSDDSELLLVNPGEMLTGSQVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_ALISL
Sequence: MLRVAINGFGRIGRSVLRALYESGKRDQIEIVAVNELSQPEGMAHLLQYDSTHGRFLHKVTHDQEYLYIDLPNGSQDRIRIVHQADISLLPWQSLQVDLVLDCTGVYGSKADGERHIDAGAKKVLFSHPGSADLDNTIIYGVNHDTLLPEHRVVSNGSCTTNCIIPVIKAIDDAFGIESGTITTIHSAMNDQPVIDAYHTDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVRVPTVNVTAMDLSVTINTNVKVNDINQTIVNASQCTLHNIVDYTEAPLVSIDFNHDPHSAIVDGSQTRVSNGHLVKMLVWCDNEWGFANRMLDTALVMKK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURK_AQUAE
Sequence: MLTVGILGGGQLGWMTILEGRKLGFKFHVLEDKENAPACRVADRCFRTGQISEFVDSCDIITYEFEHIKDEVLEKCESKLIPNPQALYVKKSRIREKLFLKKHGFPVPEFLVIKRDEIIDALKSFKLPVVIKAEKLGYDGKGQYRIKKLEDANQVVKNHDKEESFIIEEFVKFEAEISCIGVRDREGKTYFYPQPFNKHEEGILIYNYVPYAKLKEAEEITKRLMELLDIVGVFTVEFFLLKDGRVLINEFAPRVHNTGHWTLDGAYTSQFENLLRAITEMPLGSTELKLPSGMVNILGKSYEEIPLKEILSVEGAKLYWYGKEKKPRRKVGHVNVVGRSKEEVVEKVERVFTLLKGSREKLPAP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RNPH_BRUSU
Sequence: MRPSKRAADEMRAISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNTGKGWVTAEYGMLPRSTGERMRREAAAGKQGGRTQEIQRFIGRSLRAVVDMQALGEMQITVDCDVIQADGGTRTAAITGGWVALHECLRWMEARQMVRVEKVLKDHVAAISCGIYEGVPVLDLDYAEDSVAETDSNFVMTGKGGIVEIQGTAEGVPFSEEEFGALMKLARSGIDRLVSLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GS69_BACSU
Sequence: MEYTSIADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEYGKRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVAPLHTIQPPYNLFEREMEESVLPYAKDNKITTLLYGSLCRGLLTGKMTEEYTFEGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGARKPGQLEALSEITGWTLNSEDQKDINTILENTISDPVGPEFMAPPTREEI
What is the function of this protein?
Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro.  Is able to reduce the standard AKR substrates DL-glyceraldehyde, D-erythrose, methylglyoxal, p-nitrobenzaldehyde, benzaldehyde and butyraldehyde, in the presence of NADPH.  Cannot use NADH as a cosubstrate.  Does not act on glucose, 2-pyridine carboxyaldehyde, fructose and xylose.  The physiological function of this enzyme is not clear.  May play a role in bacterial stress response and/or in detoxification of reactive aldehydes.
What are the official names of this protein?
Aldo-keto reductase YhdN, AKR11B, General stress protein 69, GSP69.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 11 subfamily.
Protein: TAM_ECOL5
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVPLENIEYIADLGCGPGNSTALLDQRWPAARITGIDSSPAMIAEARSALPDCLFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLSPLGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFLTRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBRS2_HUMAN
Sequence: MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNKGSGSLDG
What is the function of this protein?
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.  May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit.  It is unclear whether it acts as a GTPase.  Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
What are the official names of this protein?
NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_STRP2
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TRXB_MYCGE
Sequence: MLKVNADFLTKDQVIYDLVIVGAGPAGIASAIYGKRANLNLAIIEGNTPGGKIVKTNIVENYPGFKTITGPELGLEMYNHLLAFEPVVFYNNLIKIDHLNDTFILYLDNKTTVFSKTVIYATGMEERKLGIEKEDYFYGKGISYCAICDAALYKGKTVGVVGGGNSAIQEAIYLSSIAKTVHLIHRREVFRSDALLVEKLKKISNVVFHLNATVKQLIGQEKLQTVKLASTVDKSESEIAIDCLFPYIGFESNNKPVLDLKLNLDQNGFILGDENMQTNIKGFYVAGDCRSKSFRQIATAISDGVTAVLKVRDDI
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSH4_MOUSE
Sequence: MCCLFLRLRDYSTAHALSLPPCQRCGLQPWSARSHARRTLGVRKAGEMLRQEAASLSSSPRWTPSRRDAPCGRTLASASRPSTEGAMADRSSSSSSSPAPASAPGSSFGNKRSYAIHRAASSFPVGTSSSSARDTTYPHTFRTPLSAGNPQRSGHKSWTPQVGYSATSSAVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSSVLMEVQSRYYCLAAAAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVLDARDITTQITRQILQNQRSSPEMDRQRAVYHLATRLVQAARNSQLEPDRLRTYLSNLKKKYAGDFPRAVGLPEKTEE
What is the function of this protein?
Involved in meiotic recombination.  Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
What are the official names of this protein?
MutS protein homolog 4, mMsh4.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Chromosome.
Protein: FRDD_EDWI9
Sequence: MMNNKVYKRSDEPVFWGLFGAGGMWGAIFAPAVILIVGILLPLGMFPDALTFERALSFSQSIIGRIFWLLMIILPLWCGLHRLHHMMHDLKIHVPASSWVFYGLAAILSVVALIGIFTL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IVY1_YEAST
Sequence: MPDNNTEQLQGSPSSDQRLRVDWDNGNHFDVSPDRYAPHLSEFYPIVNSKRPVASSAGSENNDHLDDMNHLRSSKVYSKARRASSITSGTSTINDLQTLITKRDVKETQEALSTLLRNSNAYSDSLLKTSQNGAEIAHSLENIAKLKGCNDETAEKLLSASGLFYLLSNHQLIMSKYFNDLLGDNLIDDIDEFELQTKIMENKFKAQSKEQSLKLKLQERHNFDISKRKIRNLISYRESLSSLQARLDQLETLKHDFYMDSYELVENTCNKVLSKVATVSRAQVEISENIARKGWSGGGLDELLCDADDPFSKKADGPYGTIGGDGETAGEAYNSDEETGGNDVVLNELLEGTSQPSTSKTSLPKSKGSSTVSTPNHSQSSSNKDGVRNNGGGKNGEDEDTDNLMGTENSFSLPPTRNSAEETTQTFKQLSIKEDNDNHSSDTDGMQDQSSNI
What is the function of this protein?
May be required for vacuolar fusion.  Overexpression leads to fragmentation of vacuoles, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell and accumulation of multivesicular bodies inside the cell.
What are the official names of this protein?
Protein IVY1, Interaction with VPS33 and YPT7 protein 1.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Note=Binds to various phospholipids.
Protein: SYR_RHOJR
Sequence: MTPADLAELLRGTAAKVLDERGLDVSVLPETLTVERPRNPEHGDYATNVAMQVAKKVGTNPRELAGWLAEALTAAEGIDSADIAGPGFLNIRLAADAQGAIVAKILDEGAAFGSGHTLDGKRINLEFVSANPTGPIHLGGTRWAAVGDALGRILSTQGAAVTREYYFNDHGAQIDRFSRSLIAAAKGEPAPEDGYAGAYIADIAAQVQSQRPDVLELPAGEQQEVFRAIGVDLMFAHIKRTLHEFGVDFDVYFHENSLFESGAVEKAVETLKDSGNLFQEDGAWWLKSTDFGDDKDRVVIKSDGNAAYIAGDIAYFQDKRSRGFDLCIYMLGADHHGYIGRLKAAAAAFGDDPDTVEVLIGQMVNLVRDGVAVKMSKRAGTVITLDDLVEAIGVDASRYAMIRSSVDSSIDIDLELWTSTGNENPVYYVQYAHARLSAIARNAADLGIAVADPDFSLLVSEQEGDLIRTLGEYPRVVTSAANLREPHRIARYLEELAGAYHRFYGACRILPQGDEEVGPLHIARLALCDASRQVLSNGLALLGVSAPEQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_PRUAR
Sequence: MAAAAAAARPLVTVQSLEGDMATDQTQTVALPDVMKASIRPDIVTFVHSNISKNSRQPYAVSKKAGHQTSAESWGTGRAVSRIPRVPGGGTHRAGQGAFGNMCRGGRMFAPTKIWRRWHRKINVNQKRYAVVSAIAASAVPSLVLARGHKIETVPELPLVVSDSIEGVEETSAALKVLKQIGAYSDAEKAKDSHSIRPGKGKMRNRRYINRKGPLIVYGTEGAKLVKAFRNIPGIDIINVERLNLLKLAPGGHLGRFVVWTKSAFEKLDSIYGSFDKVSEKKNGYVLPRSKMVNADLARIINSDEVQSVVSPIQEGSKRAPLKKNPLRILNTMLKLNPYAKTARRMSLLAEAERVKAKKEKLDKKRKPISKEEASTIKAAGKAWYQTMISDSDYTEFDNFTKWLGVSQ
What are the official names of this protein?
60S ribosomal protein L4, L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y774_RICTY
Sequence: MSWIIFYTIIAALLILDLGIVHKKNTVIAFKSSVFLSLFYFIISCLFGIYIYHNMGLDHAREYYTCFLIEKAMALDNIFIISIIFQFFKIPTTYQHRVLFFGIIGVIIFKAIIIYGGIMLIHKFSWLLYIFAVILIATGIKTFNVSHKTYDIQNSYIYKSIIKNLNITHNLEGHKFVIKRNNKLYFSPLFVSLILIETIDVVFAIDSIAAIFAITNDVYIIYTSNIFAILGLRSLFFCLSEIVERFSYIKYSLALILIFIGFKIFMHHYIAIPAYISLTVTITSLLLGIIASIMRKNMIDHK
What are the official names of this protein?
Uncharacterized membrane protein RT0774.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RGLA_NEOFI
Sequence: MLSKATLLLSLPFWARVANAAFGITTTSSSYVIDANSASPLKFTVNRSNCDITSINFYGAELQYQGTGSHIGSGLGSASVSATQSGDYIKVTCSTSTLTHYFVVHNGDPIIHMATHITAEPSIGELRFIARLNNELLPNEEPFGQVSNTAGGTAIEGSDVYLVNGQTRSKFYSSERFIDDHRHCVSGSAHRVCMILNQYESSSGGPFHRDINTNNGGQYNALYWYMNSGHAQTEANRMGLHGPYSMYFSRSGTPGTNIDTSFFANLDIKGYVPANARGKVSGKASGADSTFKWVVHWYNDEAQYWTYTASDGSFTSPAMKPGTYTMVYYQGEYKVASTSVSVSAGSTTTKNISGSVTTGKTIFKIGEWDGQPTGFRNAANQLRMHPSDSRMASWGPLTYTVGSSSLSDFPMAIFKSTNSPVTIKFTASSSQTGAATLRIGTTLSFAGGRPQAKVNSFTGPVPSAPKDLNSRGVTRGAYRGFGEVYDVAIPAGTIVAGTNTITISVVSGSSGDTFLSPNFIFDCVELFQ
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FAPR_EXISA
Sequence: MRVPKKERQRLLQETIEHNPFIKDEELSKQFSVSIQTIRLDRMELKIPEVRERIKHVASEHLDEVKSLSMSEVIGDMIDLKLDDSAISVLDIEKEHVFSRNEIARGHVLFAQANSLAVALINDELALTTKADIRFSRQVHLGERVVAKARVMKLRGDGRTDVTVESYVGEECVFDGDFTIYRRGEEEQA
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: ADPRH_STRPG
Sequence: MPSSFDLLGEMIDLLQTEQLTSYWACPLPNALTKRQDLWRALINQRPALPLSKDYLNLEDTYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGFPKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (PubMed:33769608).  Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L (SpyM50867), by releasing ADP-ribose from the target protein (PubMed:26166706).  May be involved in the modulation of the response to host-derived oxidative stress (PubMed:26166706).
What are the official names of this protein?
Protein-ADP-ribose hydrolase, SpyMacroD.
Protein: ISPF_SHISS
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SI25_BOMMO
Sequence: MLARCLAVAAVAVLASAGPPSPIYRPCYLDDYKCISDHLAANSKCIPGRGQIPSQYEIPVFQFEIPYFNATYVDHNLITRNHDQCRVSEFYDNVRTLKTVLTVDCPWLNFESNRTLAQHMSFKEDVVLSFYINGSYPLIRLTTVFDKGNNFDLCSAFTFADLAGGLPIFHINPNDQRTAQWLSKDLTLLHIYEREHIFGKRNWLARSFISRTLCDFGCQH
What are the official names of this protein?
Fibrohexamerin, 25 kDa silk glycoprotein, p25.
What are the subcellular locations of this protein?
Secreted.
Protein: CRVP_ECHCO
Sequence: NVDFDSESPRKPEIQNEIIDLHNSLRRSVNPTASNMLRMEWYPEAAANAERWAFRCTLNHSPRDSRVIDGIKCGENIYMSPYPIKWTAIIHKWHDEKKNFVYGIGASPANAVIGHYTQIVWYKSYRGGCAAAYCPSSAYKYFYVCQYCPAGNIIGKTATPYKSGPPCGDCPSACDNGLCTNPCTREDEFINCNDLVKQGCQTDYLKSNCAASCFCHSEIK
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels in smooth muscle.
What are the official names of this protein?
Cysteine-rich venom protein, CRVP, ECO_00025.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: BRDT_HUMAN
Sequence: MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
What is the function of this protein?
Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis (PubMed:22464331, PubMed:22901802).  Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time (PubMed:22901802).  In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA (PubMed:22901802).  Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac) (By similarity).  Also acts as a component of the splicing machinery in pachytene spermatocytes and round spermatids and participates in 3'-UTR truncation of specific mRNAs in post-meiotic spermatids (By similarity).  Required for chromocenter organization, a structure comprised of peri-centromeric heterochromatin.
What are the official names of this protein?
Bromodomain testis-specific protein, Cancer/testis antigen 9, CT9, RING3-like protein.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin.
Protein: VSH7_DICDI
Sequence: MDVQTKYGAGQNKVLGGANQKKIVESEEDIALPELNPSVPQAIQRARNALKMTQKELAFKINERPGVINEYESGSAIPSQAVLSKLEKALNVKLRGKEIGKPLK
What are the official names of this protein?
Vegetative-specific protein H7.
Protein: YHCW_BACSU
Sequence: MIKALIFDFDGLILDTETHEYEVLQEIFEEHGSVLPLSVWGKVIGTAAGFRPFEYLEEQIGKKLNHEELTQLRRERFAKRMESEKARPGVEAYLNAAKDLGLKIGLASSSDYKWVSGHLKQIGLFDDFEVIQTADDVEEVKPNPELYLLAAKNLGVSPAECLAFEDSVNGSIAAKRAGMKCVIVPNKVTGTLMFEDYDHRLESMAEMELALLLDHLNSQN
What are the official names of this protein?
Putative phosphatase YhcW.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: Y647_BACAC
Sequence: MLEKTTRMNYLFDFYQSLLTQKQRSYMSLYYLDDLSLGEIAEEFDVSRQAVYDNIKRTEAMLEEYEEKLVLLQKFQERQRLVAKLKQLISEEEHVNEEMKQVVEAIEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BAMEG_0647.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: SR45_ARATH
Sequence: MAKPSRGRRSPSVSGSSSRSSSRSRSGSSPSRSISRSRSRSRSLSSSSSPSRSVSSGSRSPPRRGKSPAGPARRGRSPPPPPSKGASSPSKKAVQESLVLHVDSLSRNVNEAHLKEIFGNFGEVIHVEIAMDRAVNLPRGHGYVEFKARADAEKAQLYMDGAQIDGKVVKATFTLPPRQKVSSPPKPVSAAPKRDAPKSDNAAADAEKDGGPRRPRETSPQRKTGLSPRRRSPLPRRGLSPRRRSPDSPHRRRPGSPIRRRGDTPPRRRPASPSRGRSPSSPPPRRYRSPPRGSPRRIRGSPVRRRSPLPLRRRSPPPRRLRSPPRRSPIRRRSRSPIRRPGRSRSSSISPRKGRGPAGRRGRSSSYSSSPSPRRIPRKISRSRSPKRPLRGKRSSSNSSSSSSPPPPPPPRKT
What is the function of this protein?
Involved in 5' and 3' splicing site selection of introns, and may bridge the 5' and 3' components of the spliceosome.  Isoform 1 is required during flower petal development and isoform 2 is involved in root growth.  Regulates negatively glucose and abscisic acid (ABA) signaling during early seedling development.  Involved in the RNA-directed DNA methylation pathway (PubMed:22274613).  Modulates KIN10 stability in response to sugars, probably through the splicing regulation of 5PTASE13, a protein implicated in the proteasomal degradation of KIN10 (PubMed:27436712).
What are the official names of this protein?
Serine/arginine-rich splicing factor SR45, At-SR45, AtSR45, Serine/arginine-rich ribonucleoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family. SR45 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with spliceosome components. During interphase, present in both nuclear speckles and nucleoplasm. Nucleoplasm-speckle shuttling protein. The intranuclear distribution and mobility depend on the phosphorylation status, ATP and transcription activity.
Protein: SYT8_MOUSE
Sequence: MQADRSMKMGHALNPFSTSAPLDATAGPSLIPDLITRIPWPRWTLFIAILAAGVLLVSCLLCVICCYCHRHRHRKQPKDKETVGLGSARNSTTTHLVQPDVDCLEPCSGGDQQWGRLLLSLEYDFGSQEIRVGLRQAGNLKAEGTADPYAWVSVSTQSGRRHETKVHRGTLSPMFEETCCFLVPPAELPKATLKVQLWDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGTTEPEQMGELCFSLRYVPSSGSLTVVVLEARGLNPGLAEAYVKIQLMLNQRKWKKSKTSSKKGTTTPYFNEAFVFLVPVSQLQSVDLVLAVWARGLQLRTEPVGKVLLGSRASGQPLQHWADMLAHARRPIAQWHHLRSPREVDRVLALQPRLPLLRPRS
What is the function of this protein?
Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.  Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.  May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells.
What are the official names of this protein?
Synaptotagmin-8, Synaptotagmin VIII, SytVIII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome.