PharMolix/UniProtQA huggingface dataset:
Protein: Y1736_LEPIN
Sequence: MKFTVYVKPNSKKVFFRKEEDGVLTIAVREPALEGKANEAVIESISKEMKVPKSKIRILSGQKNKKKIIEIDL
What are the official names of this protein?
UPF0235 protein LA_1736.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: TRPD_RHIE6
Sequence: MTDLKPFLAKAASREPLTRDEARAAFDILMSGQATPSQIGGFLMALRVRGESVDEIVGAVTTMRSKMLTVEAPADAIDIVGTGGDASGTYNISTLAALIVAGAGVPVAKHGNRALSSKSGAADNLSALGVNIDVGPEIISRCIAEASVGFMFAQLHHSAMRHVGPSRVELGTRTIFNLLGPLSNPAGVRRQLLGVFSPQWLVPLAEVMRDLGSECVWVVHGDGLDEITTTGITKVAALEDGKIRTFELSPADFGVSPCVLADIKGGDGVANAAALREVLGGAKNAYRDVSLANAAASLVISGKVETIRDGMKLAAHSLDSGATALALDKLIAVSNDID
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RS13_BORBZ
Sequence: MARISGIDLPNNKQLKIALTSIYGIGRTRALEVCNKSSISPSKIAKDLDNDEVNRLRKVIESDYIVEGKLRSEVAMSIKRLMDIACYRGVRHRKGLPLRGQRTKTNARTRKGKRKTVANKKIASK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: THIE_PELTS
Sequence: MVRRRGLSGLLEADIYGITAWEYSLGRSNIEVVAQMIEAGIKVIQYREKERPARQKYEECLKIREMTREAGVTFIVNDHVDLALLVDADGVHLGQDDLPADRVRELVGDKMIIGLSTHSPAQARAAEKMGVDYIGVGPIFATKTKKDVCDPVGLEYLEFVVKNISLPFVAIGGIKEHNIAEVSSRGAKCIALVTEIVGAEDIKAKVRALRAIISRKED
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ACL7B_RAT
Sequence: MATKNNPSPKPMGTAQGDPGEAGTLPAPEAGIRDTGSTQLKAKPKKIRKIKALVIDLGSQYCKCGYAGEPRPTYFISSTVGKRSAEMAADAGDTFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKILPEEHAVLVSDPPLSPTSNREKYAELMFETFGIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPSRVDYAGCDLTNYLMQLLNEAGHKFSDDHLHIIEHIKKKCCYAALLPEEEMSLGLDELHVDYELPDGKVITIGQERFRCSEMLFKPSLVGSTQPGLPELTATCLDRCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSPTVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC
What are the official names of this protein?
Actin-like protein 7B.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: STRAP_HUMAN
Sequence: MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.  STRAP plays a role in the cellular distribution of the SMN complex.  Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
What are the official names of this protein?
Serine-threonine kinase receptor-associated protein, MAP activator with WD repeats, UNR-interacting protein, WD-40 repeat protein PT-WD.
What is the protein family that this protein belongs to?
Belongs to the WD repeat STRAP family.
Protein: RL23_STAMF
Sequence: MSMDEGRLYKIIIRPVHSEKALNLIDKENTLTFIVDRNASKKDIKDAVELVFGVKVLKVRTLITSRGEKKAYVKLAPEHRASEIASQLGLI
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RS8_SHIB3
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RRFC_DAUCA
Sequence: WTAAANYVKIKVGTGKFARKTVVLSQKRTGTLKCATMEEIEAEKSLIEKSVKERMEKTIENVKASFNSIRTXRSNPDMLDKIKVEYYGTPTSLKSIAQISTPDSSSLLVNPYDKSSLKDIEKAIVNSDLGITPNNDGDVIRLSIPQLTADRRKELSKIVAKQAEEGKVALRNIRRDAIKSYDKLEKEKKLSEDNVKDLSSDLQKVIDEYIKKVDSIFKQKEKELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.
What are the official names of this protein?
Ribosome-recycling factor, chloroplastic, RRF, Nuclear located protein D2, Ribosome-releasing factor, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS14_MYCBO
Sequence: MAKKSKIVKNQRRAATVARYASRRTALKDIIRSPSSAPEQRSTAQRALARQPRDASPVRLRNRDAIDGRPRGHLRKFGLSRVRVRQLAHDGHLPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ATPB_RHOBA
Sequence: MSTATATGRVTQVIGSTFDAEFPEGQLPKIYNALTIQSEHKGVTIDLTGEVQQHLGGGRVRAIALGSTEGMMRGMNVVDTGKPVSVPVGKATLGRVFNVLGQPIDKRGDVQADDYWPIHRQAPPVNELSTNTELFETGIKVVDLLTPFVRGGKAGLFGGAGLGKTVILTELIARIASSHGGYSVFAGVGERTREGTDLWLEMQETEIGSTGRNVIEQTCMVFGQMNEPPGSRLRVALSALTMAEYFRDTTGADTLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKQGAITSVQAVYVPADDPTDPAPATAFGQLDAFIYLERSISEKGIYPAIDPLASNSRILDPQYVGDRHYTIARRVQTILQRYRELQDIIAILGVDELSEEDKTIVHRARRIERFLSQPFLVAEVFIGKPGEITSLEDTIRSFEGICDGKYDHLPEQAFMYVGAIEQAEEQAKKMESK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRM3_EBVB9
Sequence: MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKSDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging (Probable).  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RDGC_ACTP7
Sequence: MFWFKNVMIYRLTSPLSLESSSLEEQLRQTKFSPCSQSDISKFGWSSPLSGSELLHFSQGKQFLLVSHKEDKLLPTNVIKKETEERIAVLEEKEARKLKKTEKQAIKDDVVAMLLPRAFSKHQFTAIWLDLDAQLVYVDAGSSKRAEDTLALLRKTLGSLPVVPISFALLPSEVMTNWIAKGHTPNWLSLLEEAELKSFDTDSVIRCKRQDLESEEIAQHLQAGKFVTKLAIDWENHFSCVLNEDATLSRVKFADEVREKNDDILKEDIAQRFDADFLLMTEELKLFTQKMIEEFGGIKERI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARL1_HUMAN
Sequence: MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ
What is the function of this protein?
GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex (PubMed:9624189, PubMed:21239483, PubMed:27436755, PubMed:22679020, PubMed:27373159).  Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells (PubMed:22981988).
What are the official names of this protein?
ADP-ribosylation factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane. Membrane; Lipid-anchor.
Protein: RS21_LEPIN
Sequence: MVGIIVKDGESIESALKRFKRDCANAGIMSEIKRREYFEKPSIKKKKAIESAKRKAEKKKRLFSKKDKA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: BXD1_BOMMO
Sequence: MKLLGFFLSWVSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin D-1, BBX-D1, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: POTA_DESHY
Sequence: MSEEIIRLVNVTKEYDGVQVLDNINLYILRNEFITLLGPSGCGKTTTLRIIGGFENVTGGDILFEGKKINDVPPYKRKVNTVFQQYALFPHMNVFENIAFGLRIKKVDNKAIYAKVLQVMELMNLKGFEKRNIDSLSGGQRQRVAIARAIVNEPEVLLLDEPLAALDLKLRKEMQLELKRIQQRLGITFIFVTHDQEEALTMSDTVVVMNEGKIQQIGSPIDIYNEPKNVFVADFIGESNILDGVMLQDFLVHFHGRRFDCLDKGFSANEEVDVVIRPEDLKLVAAEEGMLTGEVQSVVFKGVHYEMMIQSSEFCWMVHSTQMEEVGNEVGLRILPNDIHIMKKVKGD
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBA3_PANTR
Sequence: VLSPADKTNVKAAWGKVGAHAGZYGAEALERMFLSFPTTKTYFPHFDLSHGSAZVKGHGKKVAKALSBAVZHLDDMPNALSALSBLHAHKLRVBPVBFKLLNHCLLVTLAABFPSZFTPAVHASVDKFLASVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-3, Alpha-3-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS10B_DANRE
Sequence: MARGDNMKSSNKSTPEPTLSKTLVESSTSSLLSESVVEPEDGQDLSSSAVCSASTVSLPPNENQPIGEHDRCRTVPVLHSIIVERYEGEKCGEMFHGEGVAYFQGGHVYKGSFSHGLMHGYGEYIWSDGLKYQGDFKVNVPMGHGTYTWLNGSTYEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCREGWGKRCYPSGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGIQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFSKDCMAEFPAFTPGLSGITTPFPDENDSSKGASQSSSNASPLGSDMVLNIQTLLNRVSEAHREQEFKQVEFAVLRHMGLLREIYSFYSSLGHEQSLDKIFPLTHLQFSRFLLDCRVHQHGVTLAQIYSLINVHSPFTAILPRECISYIIIIAYHICHKDIESSNNILAACFSKLMKQNIIPNAKSVKGHLFCHPVHAAVAMNYSDKSWEIYQALCEAHSVFTVRQFVLMLKDLCLYDNELTVSKLIRTLSVDSPAIHDGTYSNLDLEMSFLEFFEALLGCAELKGQKIQSYDESQTDASLQDHISSLSKEKEQRQSPVLAYQETELNDWMHKTQQFFNQTFLPAYELKVKVEEETFRLRDNTTTRYTEQLELKEKQEQDADGNELCPVTTTSVTSIH
What is the function of this protein?
May function as part of axonemal radial spoke complexes.  Radial spoke complexes are important for ciliary motility.
What are the official names of this protein?
Radial spoke head 10 homolog B.
Protein: CSN5_EMENI
Sequence: MQAAQLSWELENAVTLIDPQRDSLYRYDEETHKYLSDTRPWTKDPHYFKSVRISAVALLKMVMHARSGGSLEVMGLMQGYILPNTFVVTDAFRLPVEGTETRVNAQDEANEYMVSYLQSCREAGRMENAVGWYHSHPGYGCWLSGIDVSTQDMQQMSGPFVAVVIDPERTISAGKVDIGAFRTFPKDYTPPKEEQEEDEYQTVPLNKAEDFGAHASHYYSLEVSLFKSALDTEILSLLWNKYWVATLSQSPLFTTRDYGSKQMLDLSQKTRRVARGIESNPPRGGAPTQVRDQQLERVVKDGQRIVSEEVKGLLAAEVKMQLFQGIGGKQTVEST
What is the function of this protein?
Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex seems to link protein degradation to sexual development.  Required for fruit body formation.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLYA_MYCS5
Sequence: MYKNLKLNDKYVQKAINSEFKRQRNFIELIASENYVSDDVLKAQGSVLTNKYGEGYPYRRYYGSCENVDMVEQVAIDRLKEIFKVNYANVQPYSGSVANAAAIASVVPNGGKIMGLSLKSGGHLTHGYKISFSGIFYNSITYEVGKNGKLDYEEIKKIALAEKPDLIICGYSAYPRLIDFKKFREIADLCGAKLMADVAHIAGLIAGGVHPSPVGYAHVITSTTHKTFRGARGGVIMTNDEEIAKKVDRWVFPGYQGGPLFHAIAGKAIAFYEALQPSFKTYAENIVKNAKVFSEAFIKKGVEVVSGGTDNHLLLINVKSSYNITGKEAENFLEKINITINKNSIPFDELPPLVTSGIRLGTAAMTSRNFTKWEELAEIIDYSLRNLEFLNSKSKAARDKVKELKNRVLSFNKEFPILKKY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_RICBR
Sequence: MGQKVCAHGFRVGPTLIKGWDSVFYAEKQYKTLFIQDLKIRELVNKSFTQAQVSRILIERPSNKSIIININAKKPNIIIGKNGSEIDKLKKAIEKMTSLSEVYINIHEVRKFNIDAAIVAQTIASQLEKRVSFRKAMKTAIQASFKQGGQGIRVSCSGRLGGAEIARTEWYIEGRMPLHTLRADIDYSTAEAITTYGVIGVKVWIYKGEYTENKRYN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MYB_MOUSE
Sequence: MARRPRHSIYSSDEDDEDIEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVATSFQKNNHLMGFGHASPPSQLSPSGQSSVNSEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHGDSAPVSCLGEHHATPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHESSGLDAPTLPSTPLIGHKLTPCRDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQESGPPLLKKIKQEVESPTEKSGNFFCSNHWAENSLSTQLFSQASPVADAPNILTSSVLMTPVSEDEDNVLKAFTVPKNRPLVGPLQPCSGAWEPASCGKTEDQMTASGPARKYVNAFSARTLVM
What is the function of this protein?
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'.  Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
What are the official names of this protein?
Transcriptional activator Myb, Proto-oncogene c-Myb.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_PECCP
Sequence: MLAKRIIPCLDVRNGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSVEEAGQILSFGADKISINSPALADPELITRLADRYGVQCIVVGIDTWHDATTGRYHVNQYTGDEARTKVTTWETLDWVEEVQKRGAGEIVLNMMNQDGVRNGYDLHQLNLVRDVCNVPLIASGGAGTMEHFLDAFQTAHVDGALAASVFHKQIINIGELKQYLKQQGVEIRVC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_SHEB5
Sequence: MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLFAVVIYFRHELWTMFNAWIASIFRGQQSEDSKLAWWIILATLPAVFFGFLAKDFIATHLRNAEVIAVTTVVFGLLLWWADKMSRRDLTVYQTGWRKALLIGFAQALALIPGTSRSGATMTAALMLGLSRDAAARFSFLMSVPVSLGAAILVGKDLAKSELPIDYQALILGTLISFVAAYACIHYFLKIISRMGMTPFVIYRLALGAVLCGFIFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_CLOK1
Sequence: MIFLDNRQDKIEVTDKLEKIVTSSIECALKEEKVNFPCEISVVFVDNENIKDINRENRNIDRVTDVLSFPMLEYPESKVFKEVYLNYKFPEYDMNDGNLVLGDIVVSLEKCEEQSREFGHSFFRETCYLIVHSVLHLLGYDHTEDSDKKIMREREEYILKKAKL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CORGL
Sequence: MSTEQELQIGKVVKSHGIRGEVVVELSTDDPDIRFAIGEVLNGKQAGKEHSLTIDAARMHQGRLLVKFAEVPDRTAADSLRGTRFFAAPLEDEDDEDGFYDHELEGLRVIHEGEDIGEVTGVMHGPAGEILEVRLTSGKETLIPFVHAIVPEVDLEEGTATITPPEGLLDL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_THEP1
Sequence: MIVNVIGAGLAGSEVAYNLGKRGIRVRLFEMRPKKMTEVHKTGYFAELVCSNSLKSEDITNAEGLLKAEMKLMGSITLEAAEKARVPSGKALAVDRNIFAKEVTEAIESLESVEVIREEVTEFDPEEGLWVVATGPATSDGLFSFLRNLLGDDFLFFFDAVSPIVTFESIDMEHAFWGDRFGKGKDYINCPLTDGEYEELWKALVEAEVIEMEDFDRKLLFERCQPIEEIARSGKDALRYGPLRPTGLVDPRTGKEPYAVVQLRREDKEGRFYSLVGFQTRLKWNEQKRVLRKIPCLRNAEIVRYGVMHRNVYINSPKLLDIFFRLKKQPNIFFAGQITGVEGYMESAASGIYVAYNVYRILKGLSPLKLPEETMMGALFSYIIEKVEGDLKPMYANFGLLPPLKTRVKDKFGKRKKLAERAIEAMRKFLEEYPW
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_SHESR
Sequence: MSVTSLSFPYGESIQWFCADNAKNLPSSPLKEWLLAPGSLTQKLKGCCDKFEVKILGEGQCVPLEGEYPKQNAVWVREVLLCLDSVPWVFARTLIPQSLLSTRQADFLGLGTRPLGELLFSQDSFVPGRIEIARFTTDSRLAQLAQSLAQNVEHELWGRRRYFHHDEEEMFVSEMFLPAAVQAMARLQP
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.