PharMolix/UniProtQA huggingface dataset:
Protein: SHLD3_MOUSE
Sequence: MDSCRMTTEVILHYRPYENDPKQLAKIAENVIQDFPTHPLPRFIPWFPYDESKLPLKPERLPPVISEEAAESVKQYLAISEPGVKSQSYDCTVDLLEFQPSSKLQHFIQSHTVKEQTNAAHLDKNSGKEKQHKQRSWSVSLASSHCPEKIFPLSRKLQASLRTLHLHSFHRARWTLEYSVCNNQTLEDIWTKLNRLIRRDELPSCNATIQRQLGQIWVFCDIKCCEYVGNLLKERLSLIGKIDLFVHKYGVIFSM
What is the function of this protein?
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs).  During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection.  Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.
What are the official names of this protein?
Shieldin complex subunit 3, REV7-interacting novel NHEJ regulator 1.
What are the subcellular locations of this protein?
Chromosome. Note=Recruited to sites of chromosomal double-stranded breaks during G1 and S phase of the cell cycle.
Protein: ADPP_ECO57
Sequence: MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQMSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEGESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLADENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA
What is the function of this protein?
Acts on ADP-mannose and ADP-glucose as well as ADP-ribose.  Prevents glycogen biosynthesis.  The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity).
What are the official names of this protein?
ADP-ribose pyrophosphatase, ADP-ribose diphosphatase, ADP-ribose phosphohydrolase, ASPPase, Adenosine diphosphoribose pyrophosphatase, ADPR-PPase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudF subfamily.
Protein: BEGIN_SHEEP
Sequence: MWTGGRRPGRLRRAASAADMEKLRLRSAWVPSCLGQSRNLQGRRARSSPSLWDSSLQEQKGELRKRLSYTTHRLEKLENEFDSTRHFLEIELRRAQEELEKVTEKLRRIQSNYMALQRINQELEDKLFRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCSLAAQLLQCSQAYGRGRKMAELPAEFQERMNLHAEKPGCSLPAPPRRPAYADSVPPCVLAKVLEKPDPGSLSSHLSEASAQDLGFPEGLEKPGSRPPYKGDIYCSDTALYCPEARHQDRRPSVEGPGSDVGFLQAQNSTDSTAEEEEEEEEDTEAGAAAYPASYRHEAFGGYAASLPTSSSYSSFSAASEEKEHAQASTLTASQQAIYLNSRDELFGRKPAAAYGSSPRYAAAAAAVAAPLEAAMAPGFPRTVSPFPGEPFRFPLSPGPQPALMPPNLWNLRAKPGSARLVAGAGRGQWRPLSVDDIGAYPFPAAAAAPAPSLASPGGGFNDRYFGARGGPGDNAEGRASPLYASYKADSFSEGDDLSQGHLVEPRYLRAAGDLSLSPGHSADPLPSYAASEGDRERLGVQLLGASGSPEPELSLRSSRDSLEPSSMEASPEMHPGARLSPQPAFPRAGSSGLSRKDSLTKAQLYGTLLN
What is the function of this protein?
May sustain the structure of the postsynaptic density (PSD).
What are the official names of this protein?
Brain-enriched guanylate kinase-associated protein.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: Y1969_ARCFU
Sequence: MVKLLTREEGEKAVRLAREAIEHYLEERKILQKRLDGVFSQKRGVFTTLTKHGNLRGCIGFPYPVKRLDEAIIESAIAAAVDDPRFEPVRLSEMNEIIVEVTILTPPERIDAKPKDLPNHVEIGRHGLIVKMGPFSGLLLPQVAVEYNMDAEEFLSETCMKAGLPPDCWLTGAEVYRFEGQIFKEKEPRGEVVEVDIKSCGI
What are the official names of this protein?
Protein AF_1969.
Protein: EFTS_XANCP
Sequence: MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETDFVAKDENFLAFTDVVANAALNSDATDADALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDAELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYGQPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIS_SULAC
Sequence: MQISISLQGQSKIIYQIFRSYYENAVLDLPQDIELREFAYQPFNSDTYVRHLTFSSVDELRSFILSNVPLHLYFSAARYQIPSAKEMEQKGWLGSDLLFDLDADDICEINVRRFCSGMEILSETCDGEVREISEITVDCINRVFENALVLKDILIQDFGLKPRIFFSGNRGFHIRVDCYNEWANLDSEDRREIAEYIMSPSPPYESNSESGPGWLGRFARGINGVKIDEQVTVDPKRLVRIPGSLNGKAGLKVIEIVNDKFEYDEYLSPFEGIVAFQSNLSGKFNVLGHEIQLRRGEITKLSAKTGVYLALKGYGVIKAHVR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: ARND_ECO55
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: ALDOC_CARAU
Sequence: MTHQYPALTTEQKRELQDIAQRIVAPGKGILAADESTGSMAKRLNPIGVENTEENRRLYRQLLFTADERMDKCIGGVIFFHETLYQKADDGTPFAKMIKDRGIVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRSVLKISETSPSELAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAACYKALSDHHVYLEGTLLKPNMVTAGHSCPTKFSNQEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINNCPLTKPWALTFSYGRALQASALSAWRGVKENEKAATEEFLKRAEANGLAAQGKYVSSGMDGSAGQSLYVANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase C, Brain-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: ILVD_SHIFL
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALCAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GLMM_CALS4
Sequence: MGRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECALIAGLTSLGAEVVSVGIIPTPAVAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLPDKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIEFLKSTIDTDLKGLKIVIDCAYGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDGDADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKLIRTKVGDRYVLEEMIKGGYSIGGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSELASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEKEMEGKGRVLIRPSGTEPLIRVMVEGEDYAKISQMAKELADLIERKLN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RPOY_LACGA
Sequence: MIYKVLYQKDQIVNPRRETTKTLFLEADNVVAARTMVEDNTPYNIELIQELTGNSLAYEKQNPDFKLTTFKSEDK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: ATG3_SCLS1
Sequence: MNFLHSTLDRLREFTPVSNTSTFRTNGQITPEEFVAAGDYLVFKFPTWSWADASPTSKRASYLPAGKQFLVTRGVPCHRRLDDDFAGEAGHDETVVGDGEDFRGTGHSPGDDEDGWLRTGGLAASQEARARDVRTVDESGEMGEREDDEDDIPDMEDEDDDDEAIIRDPKADNANSSRRTYTIYIAYTPYYRTPRLYLSGYLSSSQPLPPHLMMEDIVGDYKDKTVTLEDFPYFSNNIKMASIHPCKHASVMKTLLDRADAALKLRREKQKQGKTVPGAKDTGMEGLVDDFEKTKISDKKAMLEGLKAGGNGNDEWEVLQHDQDFASEEEEVAIRVDQYLVVFLKFMASVTPGIEHDFTMGV
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8.  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of atg8.  The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme atg3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_CHLT2
Sequence: MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQPDWQEVPLEDFLASPPFSFSFSKDSPLQAFYGDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQGSLPKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSDLTISQILEKILPLIPSHLT
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAC6_ORYSJ
Sequence: MSCSWMIPVFAILAFVASAAQADVVEHTFNVATLSLPRICQPGNTSVTAVNGRVPGPQVEAREGDTVVIHVINDSPYNVTVHWHGVFQRGTPWADGPAMVTQCPIRPGHRYTYRFAVAGQEGTLWWHAHSSYMRATVYGALVIRPRRAGGYPFPTPYEEKTVLLGEWWNGDPVALESQSFSTGIPAPNADAYTINGMPGDSYLCPETTNRIAKFEVRRDKTYLLRIINAALNTAFFFKVAGHTFTVVAADASYTEPYATDVIVIAPGQTVDALMAADASPGCYHMAISSYQSAIPFPPRPAGFNGNTSTAIVEYVDATATTDAGSPVLPVMPKPNDTYTANQFYTSLTALIRPGRRTVPLTVDTRMLVTVGLGFSSCQPEQTQCNRSAPVVLANMNNVSFALPNTVSMLEALYRNTADGVYTRDFPDQPPVAFDYTSRGLLGNSPLASTGSPSTKVKTLRYNATVEMVLQNTALVGLESHPMHLHGFNFFVVAQGFGNNDGEAAGAGEFNLVNPQERNTVAVPTGGWAVIRFVADNPGMWAMHCHIDSHFAIGLAMVFEVESGPTPGTTLPPPPPDLPQC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-6, Benzenediol:oxygen oxidoreductase 6, Diphenol oxidase 6, Urishiol oxidase 6.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: 3LKA_BUNCA
Sequence: MKTLLLTLVVVTIVCLDLGYTRTCLISPSSTPQTCPQGQDICFLKAQCDKFCSIRGPVIEQGCVATCPQFRSNYRSLLCCTTDNCNH
What is the function of this protein?
Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors (nAChR) with high affinity (IC(50)<100 nM).  Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs.
What are the official names of this protein?
Kappa 1a-bungarotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Kappa-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APTX_SCHPO
Sequence: MSVHKTNDAFKVLMNSAKEPIVEDIPKKYRKQSFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM
What is the function of this protein?
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair.  Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:24362567, PubMed:21984208).  Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:24362567, PubMed:21984210).  Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (PubMed:26007660).
What are the official names of this protein?
Aprataxin-like protein, Hit family protein 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PURA_ECOLC
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELP4_CAEEL
Sequence: MLNVGDSVQIAGCSTKKRLLETSSGCDSFDTLIGGALVNSSIVLIDEYRSRCYGSYLIRSFLAEGLHHGHRCFIADPTEDPKEINLIPSRRTSTDMQNQEIPNSLPAENENSMKIAWRYGNVKQVSSSLGPLSNENQYDFTKHVENPNVDVYAEKVFTLKGIYETLCQIVKENEAHTKSGGRGGPKKNLLRVVLKNIDMEICEDYKFLGRFLCCLRSLARSSYMIVYITANSFRVPKPTWRILESAADTHIQLMPFDENEKKMFKHLGTAHGYFHLKSLPRLMSVGTHTPPILDLIFEASSRKGFQIRVMHLPPAFDEPAPGHQNTPSCQNIDF
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).  The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
What are the official names of this protein?
Elongator complex protein 4, ELP4.
What is the protein family that this protein belongs to?
Belongs to the ELP4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS2_BRUAB
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMAPFIYGERNNIHILDLSQTVPLLNSALKVVSDTVARGGRVLFVGTKRQASDIIADAANRSAQYYVNARWLGGMMTNWKTISNSIQRLRKLDELLAGEAQGFTKKERLNLEREREKLDRALGGIKDMGSVPDLMFIIDTNKEAIAIQEAKRLGIPVVAVIDSNCDPDQIDYPIPGNDDAARAIALYCDLIARAALDGIARQQGAMGIDVGAQVEAPVEPALQAPAEGA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y2558_MYCPA
Sequence: MDGTDAEAPGQTAPSRAESLVAHAEASISEDALLAAARERAVDIGAGAVTPAVGALLSLLTKLSGGKAIAEVGTGAGVSGLWLLSGMSDDGVLTTIDIEPEYLRLAKQAFAEAGIGPSRTRLIGGRAQEVLTRLADEYYDLVFIDADPIDQPDYVVEGVRLLRPGGVIVVHRAALGGRAGDPAARDAEVVAVREAARLIAEDERLTPALVPLGDGILAAVRD
What are the official names of this protein?
Putative O-methyltransferase MAP_2558.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: MVP_RDVF
Sequence: MDTETLCLITADSGKVYGILKAIFGDESEIVKKLIDFDVSIRVVPLNLGLLNIFRDNAADLDNADLMKRRFGNTMGSRIVEAYRRSQDSKYKRNVCKTTGLLVCLFGGGLGLSREADKHKKFVEGKSHNILSVEMLKRALSIGGQNVDANKISSFWFATYTIFTTVYSPRLRYQAGSSKRIIALSESRNQYRSNLFWDLRDDSSHEVMSMVHVLSALFASALTAYISTRVRHELTQGNDERESLNNVLVWLKTLTFEPSTIALIAYIWLVSPTDAQATITIGSVMESESSDDFPDIVKILSYTSNTMLPVQLLEDGRTAYCSVADGYTRHTTALTLITDYNSSHMSDKFGVLINIVKFEHAYALHYVHHKPRDGKEMTITSPSSEMMFTSVVVTPLSSYPLIHARNAVIDWLRTFVHMFPDSGSLVIPADSYTWIHNLAQDMFPWVQLSTTLDIRDDHYFQVLCDCLSLGRDSRNHAKVEKLIKYMKASVYNFTSEARGNMLLAITVYK
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.
What are the official names of this protein?
Movement protein, Non-structural protein 6, Pns6.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PHNS_SALTI
Sequence: MKLSRLALLSVFALASAPSWAESVVTVYSIDGLHDGDNSWYQVQFDAFTKATGITIRYVEGGGGVVVERLAKERTNPQADVLVTAPPFIQRAAAEKLLANFNTDAASAIPDANNLYSPLVKNYLSFIYNSKLLKTAPASWQDLLDGKFKNKLQYSTPGQAADGTAVMLQAFHSFGSKDASFAYLGKLQANNVGPSASTGKLTALVNKGEIYVANGDLQMNLAQMERNPNVKIFWPANDKGERSALAIPYVIGLVQGAPQSENGKKLINFLLSKEAQTRVSELSWGMPVRSDVTPSDEHYKAATAALEGVQSWQPNWDDVAVSLSADISRWHKVTESE
What is the function of this protein?
Probably part of the PhnSTUV complex (TC 3. A. 1. 11. 5) involved in 2-aminoethylphosphonate import.
What are the official names of this protein?
Putative 2-aminoethylphosphonate-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y163_ABVP
Sequence: MMIKDLELTLKNLVSSNLDSNCVHVTNMISYGDPPTQEMLVRGKLYHLAIENLIQQVFKDAIIEQSHRDNIGNKEICYTPDVYVPSKKLLIEIKSSDRSLAYATKQTSIYRYLLERKGVSVDQCIMITGDLKVFPLQCDSNYGQQLLNSYLNSRLDQNLFKPK
What are the official names of this protein?
Uncharacterized protein ORF163.
Protein: TM231_BOVIN
Sequence: MALYELFAHPVERGYRAGLCSKAALFLLLATALTYIPPLLVAFRSHGFWLKRSSYEEQPTVRFQHQVLLVALLGSEPGGFLAWSTFPAFNRLQEGHLRVPLVSAREEDRNQDGKMDMLHFKLELPLQSTEQVLGVQLILTFSYQLHRMSTFVMQSMAFLQSSFALPGSQLYVNGDLRLQQKQPLGYGGLDVRYNVSVINGTSPFASDYDLTRIVAAYQERNVTTILTDPSPIWLVGRAAEAPFVVNAVIRYPVEVISYLPGFWEMIKFAWIQYVSILLIFLWAFERIKRFVFQNQVVTTIPVTAMPQGELYKEHLS
What is the function of this protein?
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
Transmembrane protein 231.
What is the protein family that this protein belongs to?
Belongs to the TMEM231 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone.
Protein: HIS4_LEPIN
Sequence: MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLGVNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNYGKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNLEAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISSI
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_XANCB
Sequence: MSNDTQPTIAIIGYGSQGRAHALNLRDSGFDVTVGLRPGGPTEAKAQADGFTVVAPAEAVKTADLVAVLTPDMVQKKLYEEVIAPNMKQGACLLFAHGLNVHFDMIKPRADLDVVLVAPKGPGALVRREYEIGRGVPCIYAVYQDTSGKAEQFALTYAGGLGGARANIIKTTFKEETETDLFGEQAVLCGGASSLVQAGFEVLVEAGYQPEIAYYEVLHELKLIVDLFYEGGITRMLEFVSETAQYGDYVSGPRVIDASTKARMKDVLTDIQNGTFTKNWVAEYEAGLPNYTKFKQADLEHPIEEVGKKLRAKMVWLNGEQQAAATPAKQQAA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PCAF_PSEPU
Sequence: MRDVFICDAIRTPIGRFGGALAGVRADDLAAVPLKALIEPNPAVQWDQVDEVFFGCANQAGEDNRNVARMALLLAGLPESIPGVTLNRLCASGMDAIGTAFRAIASGEMELAIAGGVESMSRAPFVMGKAESGYSRNMKLEDTTIGWRFINPLMKSQYGVDSMPETADNVADDYQVSRADQDAFALRSQQKAAAAQAAGFFAEEIVPVRIAHKKGETIVERDEHLRPETTLEALTKLKPVNGPDKTVTAGNASGVNDGAAALILASAEAVKKHGLTPRARVLGMASGGVAPRVMGIGPVPAVRKLTERLGVAVSDFDVIELNEAFASQGLAVLRELGVADDAPQVNPNGGAIALGHPLGMSGARLVLTALHQLEKSGGRKGLATMCVGVGQGLALAIERV
What is the function of this protein?
Catalyzes thiolytic cleavage of beta-ketoadipyl-CoA to succinyl-CoA and acetyl-CoA.
What are the official names of this protein?
Beta-ketoadipyl-CoA thiolase, 3-oxoadipyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: SSP12_PHAJA
Sequence: KPEEDWGHR
What are the official names of this protein?
Skin secreted peptide P1-2, PjP1-2.
What are the subcellular locations of this protein?
Secreted.
Protein: PA2A4_BUNMU
Sequence: MNPAHLLVLSAVCVSLLGAANIPPQHLDLYQFKEMIRYTIPCEKTWGEYADYGCYCGAGGSGTPIDALDRCCYVHDNCYGDAANIRDCDPKTQSYSYKLTKRTIICYGAAGTCARVVCDCDRTAALCFGNSEYIEGHKNIDTARFCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 beta-bungarotoxin A4 chain, Beta-BuTX A4 chain, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.