PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_RICRS
Sequence: MTNILSPEKSENDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNEHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKSTSGPAILKVADLAAILTNLEKNDVLFIDEIHRLNTAVEEVLYPAMEDFELDIIIGEGSAARSVKITLPKFTLIGATTRLGLLSNPLRDRFGIPMRLNFYNTEELKKVLNRASKLLDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVEGKSRVDKEVSDFGLNRLEVDRIGLDSNDYRYLKFIADNYNGGPVGIETIAAALSEQRDALEETIEPYLIQIGLLQRTPRGRVITIAAFEHLKMSVPNQSHHQFNIFNENE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DXS_CHLMU
Sequence: MISPLLQHISSPQKLRSLSLDQLPLLCDEIRNRIIATLSLTGGHLASNLGIVELTVALHYVFASPEDQFIFDVGHQAYVHKLLTGRNTEAFSNIRHDNGLSGFTSPQESNHDIFFSGHAGNALSLALGLAKGASHGSSHILPILGDAAFSCGLTLEALNNVPSDLSKFIIVLNDNQMSISENVGNIPQGISQWIQPPKFDKIFQKIHSWMRKIPGFSRQKSELLHKVDIALKSLSHPLFEQFGIHYVGPFDGHNIKKLIPALEAVKGLPYPVLFHVCTAKGNGLAEAEKDPALYHGVKAYFKNHSPKKKPLSSEVKTPSSFPQHVGHILCQLGEKHPRLQVVTPAMSLGSCLEDFRKQFPDRFTDVGIAEGHAVTFSAGIARSGTPVVCSIYSTFLNRAMDNVFHDVCMQELPVIFAIDRAGLAFHDGRSHHGIYDLGFLCSMPNMVVCQPRNASVLERLLFSSLLWKSPCAIRYPNLSTRKEVSNPSFSPIFPGEAEVLCQGDDLLLIALGHMCDTALAVKEQLLDHGISTTVVDPIFIKPLDTELLQTLLSHHSKVVVLEEHSIHGGLSAEFLLFLNNHNLKTDVLSLGIPDIFIPHGNPETILNMIGLTSDQITLKILAHFNFSAPIPI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RK20_NASOF
Sequence: MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHEMGVFYSYNRFIHNLYKKQLLLNRKILAQIALLNRSCLYTISNEIKE
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DSE1_DEBHA
Sequence: MNEYYEPTLLFRQNAVKKYSPELSPVSSMSSLDLPKSNNSSSSWLLDNHNPKDTEILNKSCSLNRLNIKSNYWKIPDNDMSLTSMALSRQGDSNKSLLGISSANDDSNLFIYELDLAENYLTHNNTISLPNVHAMRWVPQMGNNELSLITGNSKGYAHLVSIPNSNEEGQSAEIVKRFNHRKHLKSINKDPSIASHTSTDITKLNFMDKSMDLLSLYDNNLFLWDINGCDSQVRPKPISISSIPGIVNFDPIPHSSNSVGICGQFGVSLFDTRQPKFSVPSSVMKQANKRKLGANVIRWSPNDDNVFAASHMDGVIRLWDIRKQDYFASLDGHQGKKIISIEWNKNDLFSGGRDGNIVHWDLTSDINEYPKPDITNCGLKEGLNSIKFNPVKNSVEKTINQRQCGTVLPASNTNIVDMCSVSLTSHNEEDVKVLSIDSSSFLGLHSKIFDAVKVNINSEKTYYTDDDISLLLAAQQSSLSTLVNDSTENVTKPLTISRMPTTKITHDVAPPAIPTPASVVPTTPNMSNDTLAEGPDEFVEVGDIIRLKEPKFSFSNYNDSVFSVDSNHDIKSSPSSTTSRGSFGESSSSISTNPTIVEASPISHKRDPSDIFNFKTDFDFGLGLNDYKFDESLVDRSFDRMLSLKTNATNYYSVYSS
What is the function of this protein?
Involved in cell wall metabolism and required for the separation of the mother and daughter cells.
What are the official names of this protein?
Protein DSE1, Daughter-specific expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DSE1 family.
Protein: TXL_EISFE
Sequence: MSAKAAEGYEQIEVDVVAVWKEGYVYENRGSTSVDQKITITKGMKNVNSETRTVTATHSIGSTISTGDAFEIGSVEVSYSHSHEESQVSMTETEVYESKVIEHTITIPPTSKFTRWQLNADVGGADIEYMYLIDEVTPIGGTQSIPQVITSRAKIIVGRQIILGKTEIRIKHAERKEYMTVVSRKSWPAATLGHSKLFKFVLYEDWGGFRIKTLNTMYSGYEYAYSSDQGGIYFDQGTDNPKQRWAINKSLPLRHGDVVTFMNKYFTRSGLCYDDGPATNVYCLDKREDKWILEVVG
What is the function of this protein?
Pore-forming toxin that defensively acts against parasitic microorganisms by forming pores in sphingomyelin-containing membranes (PubMed:9478988, PubMed:12676961).  Has hemolytic activity and is also cytotoxic to spermatozoa of some species of invertebrates and many species of vertebrates and to amphibian larvae, guinea pig polymorphonuclear leukocytes, chicken fibroblasts, normal spleen cells and various tumor cells (PubMed:10684578).  Is lethal for various species of reptiles, amphibian, birds and mammals.  Induces smooth muscle contraction (PubMed:9210594).  It binds sphingomyelin and induces hemolysis in the same manner as lysenin-related protein 2, and is 10-fold more effective than lysenin-related protein 1 (PubMed:15274631).
What are the official names of this protein?
Lysenin, Beta-barrel pore-forming toxin, Beta-PFT, Invertebrate cytolysin pore, efL1.
What is the protein family that this protein belongs to?
Belongs to the lysenin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a beta-barrel pore in the membrane.
Protein: RUVA_ACIET
Sequence: MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLLYGFGTAQERQAFRELIKISGVGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKTAERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYNDKEAAAALKALPADVGVSEGIKLALKSLSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL1_KOCRD
Sequence: MAKRSKAYRAAAEKIEAGKFYAPAEAVALAKELAEGSKSDPTVEVAMRLGVDPRKADQMVRGTVNLPNGTGKTARVVVFATGDKAAAAEAAGADFVGNDDLIARIQGGWTDFDAAVATPDMMGKVGRLGKILGPRNLMPNPKTGTVTMDVAKAVNDIKGGKIDFRVDKHSNLHFIIGKASFDAQKLAENYGAALEEVLRLKPSASKGRYITKATVATTFGPGIPVDPNATEVTTQA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: WECG_ECOLU
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: MCU6_ARATH
Sequence: MWSMGLIRRTAMSNAIRASSQRTWLGHGGLRSCVTVKTPSEDEEEKKKEITIAEAKKLMRLVNVEDMKKKLVGVADRDVVSYSTLLEASQGMGIARSPDEAHVFARVLDDAGVVLIFRDKVYLHPDKVVDLIRRAMPLDQNPEEDQIKEEFNKLRIMKEEIDVLAHRQVRKILWCGLATSMVQIGLFFRLTFWEFSWDVMEPITFFATATGIIVGYAYFLMTSRDPTYQDFMKRLFLSRQRKLLKSHKFDCERFKELERLFKMTSSCHAAASIRNRVGLELDLEDALQSRRD
What is the function of this protein?
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria.  Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
What are the official names of this protein?
Calcium uniporter protein 6, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MCU (TC 1.A.77) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COBQ_PROM5
Sequence: MEFTENYNPKNKPIMVLGTSSGAGKSLTVTAICRILKKLGEEPIPFKGQNMSNNAWVDSNGGEMAYSQALQAFSCGINPSSEMNPILLKPQGDSTSEVIHLGKSVGISTAKDYYKDWFMPGWEVIKKSINIIYEKNKNCRLIIEGAGSPVEMNLIHRDLTNLRVAKYLDASCILVTDIERGGVFAQIIGTLELMKPEERKLIKGILINRFRGDLSLFKEGKKWIEDKTKIPVLGIIPWLNDKFPPEDSLDLLERKSYLSNPEIKVGIIKLPSISNFSDFDPLENENSILIEWISEAQNLNQFDFIIIPGSKQTIKDQLFLNESGLSKEIKNYSHNNGNIFGICGGLQMLGTVLEDPFFKEGSNFNSDQSIKGIGLLPLKTTFLKHKITRQIHSESIWPNSTKIIGFEIHNGITKLDSSHLDTLKTNHIFKDFDLGWYKENREGGTIAGTYIHGIFENDEWRDHYINLIRKTKNKLTLDKKSRSYKMKRESIINNLANEFNNHFNISLLLN
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SSH4_YEAS7
Sequence: MYVTFNEALDSSFGNLESPNHDFKVGDPNMVPTPPMDSDSAAISLAFLISLSITFAILMLILVVIAAYVTFCGDDESEYDEENALGTRTSGTLHSLFGKKHSGILLDSSFASPGGFDDEIVLQERELEELPKMSAYEVELYIRAKEFQMMSPPMVKDFGTYLDSDDQQFIKDRGIQSYFLLPSINDNIDEYGNFLPSFIVQDKLDIQFSKFNKSSSTVMNYPLPHNRKDAVYFEVKIFRHIQKSNSIFSIGLTTVPYPYFRVPGMAKYSIAYESTGKLRINNPFTASTLLPKLEEGDTVGFGYRYKTGTIFITHNGKKLMDVTQNIGIDLFIGIGAFNAAYTRTYTRDGLLEDPDNVSFREALSEGKDIEVAKDLQRVHDPHDDSDEMTSDEVELHVNLGQVGFVFIEANVKKYAFGSVYGQIGIPPAYNGTEIKKDTILQKGEELPPRYADTDNFFGSMKVKEGSSSRITAQTSKPLWSVGTYERISSNFDRENNVYHDSLETDDNNTDNNVNNNDENAGCNENSPLLEDDGNKRPENSNTPREVSDGAINKNPRNKSTKKRQRNRGKSSKKKNRSRK
What is the function of this protein?
Components of the endosome-vacuole trafficking pathway that regulates nutrient transport.  May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.  Confers leflunomide resistance when overexpressed (By similarity).
What are the official names of this protein?
Protein SSH4, Multicopy suppressor of leflunomide protein 4, Suppressor of SHR3 null mutation protein 4.
What is the protein family that this protein belongs to?
Belongs to the SSH4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: EBF2_ARATH
Sequence: MSGIFRFSGDEDCLLGGSMYLSPGSCPGVYYPARKRLRVAATSFYSGFEEKQTSIDVLPEECLFEILRRLPSGQERSACACVSKHWLNLLSSISRSEVNESSVQDVEEGEGFLSRSLEGKKATDLRLAAIAVGTSSRGGLGKLQIRGSGFESKVTDVGLGAVAHGCPSLRIVSLWNLPAVSDLGLSEIARSCPMIEKLDLSRCPGITDSGLVAIAENCVNLSDLTIDSCSGVGNEGLRAIARRCVNLRSISIRSCPRIGDQGVAFLLAQAGSYLTKVKLQMLNVSGLSLAVIGHYGAAVTDLVLHGLQGVNEKGFWVMGNAKGLKKLKSLSVMSCRGMTDVGLEAVGNGCPDLKHVSLNKCLLVSGKGLVALAKSALSLESLKLEECHRINQFGLMGFLMNCGSKLKAFSLANCLGISDFNSESSLPSPSCSSLRSLSIRCCPGFGDASLAFLGKFCHQLQDVELCGLNGVTDAGVRELLQSNNVGLVKVNLSECINVSDNTVSAISVCHGRTLESLNLDGCKNITNASLVAVAKNCYSVNDLDISNTLVSDHGIKALASSPNHLNLQVLSIGGCSSITDKSKACIQKLGRTLLGLNIQRCGRISSSTVDTLLENLWRCDILY
What is the function of this protein?
Component of SCF(EBF1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including EIN3 and EIL1).  Regulator of the ethylene signaling cascade by modulating the stability of EIN3 and EIL1 proteins.
What are the official names of this protein?
EIN3-binding F-box protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXH_SALTI
Sequence: MSDNNQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACDARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLLFPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: DNLJ_VIBA3
Sequence: MKESIQVTLEQLRETLHYHAVRYYVEDSPEIPDVEYDRLMQQLLKIEDENPELVTVDSPSQRVGGQPLDGFTQVTHEIPMLSLDNAFSDDDLDAFNKRMSDRAPTANLETFCCEPKLDGLAVSLLYVNGTLVQAATRGDGATGENITENVRTISSIPLKLQGEGWPERIEVRGEVFMPKAGFDKLNEMALKKGEKVFVNPRNAAAGSLRQLDSRITAKRPLAFYAYSVGVVQGAELSNSHYQRFLQLKAWGLPMCPETKQLSSLEDVKAYYQDIMTRRDTLAYEIDGVVIKVDDIAAQETLGFVARAPRWAIAYKFPAQEEITLLNDVEFQVGRTGAITPVAKLEPIFVGGVTVSNATLHNADEIARLGVKVGDSVIIRRAGDVIPQIVAVVQDRRPETAKDIVFPDACPVCNSAVERVEGEAVARCTGGLVCQAQRKEALKHFVSRKALDVDGLGVKVIEQLVDREMVETPADLFKLSAGVITVLDRMGPKSAQNVVSALNKAKDTTLARFLYSLGIREVGEATAMNLAQHFKTLELVQAATHEQLVEVSDIGDIVASHLTSFFSQEKNRAVVDQLIELGVNWPAIEAVADDQELPLEGKVVVLTGSLSKLGRSEAKAALQALGAKVTGSVSKKTDILFAGEAAGSKLTKAQDLGIEIRTEEDLIALIS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GATA_GLOVI
Sequence: MTSIGQLRSQVASKERSAVEVARQYLERAERLDTEVHAFLRLTPERALAAAEAVDAKIARGEDPGLLAGVPVAVKDNLCMVGIPTTCASKILENYRPPYESTVTRRLEEQGALIIGKTNLDEFAMGSSTENSAFGPTRNPWDLGRVPGGSSGGSAAAVAACEAVASLGSDTGGSIRQPASFCGVVGLKPTYGLVSRYGLIAFASSLDQIGPFTRTVEDAALVLQAIAGHDPLDSTSLAVNVPDYRQALISDLKGVKVGFVKEFFAEGLDPDVADAVFEAIEVMRDLGAQIQEVSCPRFARGLSTYYIIATSEASANLARYDGVKYGLRDREADALVPMYGRTREEGFGSEVKRRIMLGTYALSAGYYDAYYLKAQKVRTLIKQDYLDAFAKVDVLVGPTAPTTAFAFGDKVSDPLSMYLSDIYTIPLNLAGVAGASIPCGFDAKGLPIGFQIMANALEEGKLLRAAYAYEQATEWHKRTPALAAEALTR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GLPK_GEOSM
Sequence: MEYLLSIDQGTTSSRATLYAASGETLATVSRPLVQHYPNPGWVEHAAQEIWEGQLACIAEAIAKAGIAPAKVAGIGITNQRETTVVWERETGEPLHRAIVWQDRRTAELTESLKEQGLEAMVRERTGLLLDPYFSASKLSWLLDRVDGLRRRAERGEVCFGTIDSWLMFKLSGGKSHLTDISNASRTMLFNINTLEWDEELLRLFRIPRGMLPEVRGSAAGFGHTSAQVAGAEIPIAGVAGDQQAALFGQGCFAPGMAKATFGTGAFVVMNSGARLGVGDGVLSTIAWQLPGEAVQYALEGSIFIAGAAVQWLQEGLGLIASAREVEALAASVSDSAGVYFVPALSGLGTPYWDPYARGVIAGLTRGSTKAHLARAALEAIAFQTLDAIRAMEKASGIALKELRVDGGAAADNLLLQIQADLLGVPVLRPRCTESTSLGAAFLAGIGAGVLDTSAIAAQWALDRRFEPQMERNLREELHRGWQKCVRLSLGWEKN
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL14_SACD2
Sequence: MIQTQSYLDVADNSGARRVMCIKVLGGSHRRYAGVGDIIKVTVKEAIPRGKVKKGQVMNAVVVRTKKGVRRADGSLIRFDDNAAVILNAQNAPVGTRIFGPVTRELRGEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ACHE_RAT
Sequence: MTMALLGTLLLLALFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIEWQDYRLNFSKDDFAGVEILRVPSEHVWLPEIVLENNIDGQFGVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIFAVDDDGNAINKIDIDTAAFTENGEWAIDYCPGMIRHYEGGSTEDPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGLSPPPEDPGAASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAAALCQNLGAAAPEVRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Epsilon/CHRNE sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RS12_CLOBK
Sequence: MPTISQLVRKGRKTIASASDSPALKECPQKRGVCTVVKTTTPKKPNSALRKVARIRLTNGYEVTAYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDAAGVANRMQSRSKYGAKKPKQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TECTA_MOUSE
Sequence: MNYSSLLRIWVSFIFALVRHQAQPRELMYPFWQNDTRTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHNGIRGEIYYRETMDPAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTIKCRCLDFNNEIYCQEASCSPYEVCEPKGRFFYCSPVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRGGSAVSWVKELSVEVNGYKILIPKGSYGKVKVNDLVTSLPVTLELGAVKIYQSGMSTAVETDFGLLVTFDGQHYASISIPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCGSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDATAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRIQTGCVSTVRCPSFSHYSVCTSSCPDTCSDLTASQNCATPCTEGCECNEGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCRSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAAYAFPSELSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGVRILVADQEVKIGGVGALEVKLNGQDVELPFFHPSGRLEIHRNKNSTTVESKGVVSVQYSDVGLLYIRLSTMYFNCTGGLCGFFNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECMTCTETCETLALGPICVDSCSEGCQCDEGYALQGSQCVPRSECGCNFEGHQLATNETFWVDQDCQIFCYCNGTDNSVHCETIPCRDDEYCMEESGLYYCQPRTDASCIVSGYGHYLTFDGYPFDFQTSCPLILCTTGSRPISDSFPKFIVTAKNEDRDPSLALWVKQVDVNVFGYSIVIHRAYKHTVLVNNERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNGTYGLCGRYNGNPDDDLEMPMGLPALSINEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAGFAKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGIAVTGWRNYTSCSVTCPPNSHYESCVSVCQPRCAAIRLKSDCNHYCVEGCQCDAGYVLNGKSCILPHNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRQCKSDEECALRSGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSSPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDMTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAATCDNVHIQAMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELDNGGELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCSGIEGEDFISFQINNTKGNCGNIVQSNGTHIMYKNTIWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFTTKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADSTHLILTLNKCYATPSRDSNDKLRYFIIEGGCQNIKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQNSRIATDYSKEHKEQIISVGPIRRKRLDWCEDNGGCEQICTSRVDGPLCSCVTGSLQEDGRSCRASNSSVELQVWTLLLIMTQISLWHLIYKSGATS
What is the function of this protein?
One of the major non-collagenous components of the tectorial membrane (By similarity).  The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells.  Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
What are the official names of this protein?
Alpha-tectorin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Note=Found in the non-collagenous matrix of the tectorial membrane.
Protein: TORD_AGGAN
Sequence: MLHHNQMVLMGLLNMLKISIQERQFVYSWICSLLSKELTQDQLAHYQRGDFDSLFAFLKELGFTEQTEQLIATLRPMEFQQLELAADFAHTFLLEGNISAIPYMSAYLQGEELGVALNLVDQWMTHYQLGVNREQNEPSDHVSVLLAILIRLIGEQPFHVQQDFAQKALLNWLPEFVRKANNTSCETKFYAMLCNLFLAFMTEDFAV
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_DEHMB
Sequence: MAEKYNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSGNLHIGHWYAEVPADCFARYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDREVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVVDGTCWRCETPTTRRDLEQWFFRITNYADELKDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFEKEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTEREKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVITVIAPSAYDGKPLEAAYINEGVMLNSGPFNGTPNTEGKEKVCDYLAEHGWGKKTVNYKLRDWLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVGFRSGGESPLKYNEGFVNTICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHAVMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSNHQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLSGMSRWLNRVWNLFTEEYTPQTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMELSNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANLGMKYSIHNQNWPTWDEELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVPGKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y734_CHLTR
Sequence: MKKFIYKYSFGALLLLSGLSGLSSCCANSYGSTLAKNTAEIKEESVTLREKPDAGCKKKSSCYLRKFFSRKKPKEKTEPVLPNFKSYADPMTDSERKDLSFVVSAAADKSSIALAMAQGEIKGALSRIREIHPLALLQALAEDPALIAGMKKMQGRDWVWNIFITELSKVFSQAASLGAFSVADVAAFASTLGLDSGTVTSIVDGERWAELIDVVIQNPAI
What are the official names of this protein?
Probable lipoprotein CT_734.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0875/CT_734/TC_0107 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.