PharMolix/UniProtQA huggingface dataset:
Protein: EF2_THEAC
Sequence: MGRKEDNIEKALKIVEHTELIRNIGIVAHIDHGKTTLSDNLIAGAGMMSEELAGKQLVLDYDEQEQARGITINAAVASMVHTFQGKEYLINLIDTPGHVDFGGDVTRAMRAVDGVIVVVDSVEGVMPQTETVIRQALREHVKPVLFINKIDRLINELRLNSDEMQKRFTKIITDVNRLISKYAPQQFTKEWQVSVQDGRVAFGSAYNNWAISIPAMAETKITFKDIVEYVKNGKQKELAQKNQLHKIILNMVIRHLPDPKTAQSYRIKQIWKGDLDSEIGKAMINCDYKGPVAMMVTKIIIDPHAGEIAIGRLFSGTVKKGTDLYISGAGKGKVQTLAMMVGPDRIPVDEITAGNIAAIVGLKGAIAGATVSSLENMVPFEPMIHYSEPVVTLAIEAKHTADLPRLIEVLRDISKADPSIQVDINQETGEHLISGMGELHLDVTLYRIKNDYKVEVETSDPIVVYRETVEKKGGPFEGKSPNKHNRFYFEVEPLKPEVIQAIEDGDIPQGSKFKDKKALVELLVSKGIDRDEAKGLVCVEGTNMMFDVTRGIQYLDETMELLIEAFVEVMNRGPLANEKVFGVKARLVDAKLHEDSIHRGPAQVIPAGRNSIYGAMCEAKRVLLEPVQRVFINVPQEEMGAAINEIQQRRGIIEDMKQEGDEISLTAKVPVAGMFGFASAIRGATGGKVLWSFENAGYQKVPPELQDSIVRSIRERKGLRQEPYDADYYASM
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_SYNEL
Sequence: MATKFPKFSQDLAQDPTTRRIWYAIAMAHDFESHDGMTEENLYQKIFASHFGHLAIIFLWVSGSLFHVAWQGNFEQWVQDPVNTRPIAHAIWDPQFGKAAVDAFTQAGASNPVDIAYSGVYHWWYTIGMRTNGDLYQGAIFLLILASLALFAGWLHLQPKFRPSLSWFKNAESRLNHHLAGLFGVSSLAWAGHLIHVAIPESRGQHVGWDNFLSTMPHPAGLAPFFTGNWGVYAQNPDTASHVFGTAQGAGTAILTFLGGFHPQTESLWLTDMAHHHLAIAVLFIVAGHMYRTQFGIGHSIKEMMDAKDFFGTKVEGPFNMPHQGIYETYNNSLHFQLGWHLACLGVITSLVAQHMYSLPPYAFIAQDHTTMAALYTHHQYIAGFLMVGAFAHGAIFLVRDYDPAQNKGNVLDRVLQHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQFIQAAHGKLLYGFDTLLSNPDSIASTAWPNYGNVWLPGWLDAINSGTNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYAFPCDGPGRGGTCDISAWDAFYLAMFWMLNTIGWVTFYWHWKHLGVWEGNVAQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGTNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFSVGYILTYAAFLIASTAAKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: GVPD1_HALSA
Sequence: MSSPNLAHPPTDYTGIVLFPRELSQFFMGDAGETLLINGAPGTGKTLFTIRGLDVLDRDSDVLYVSTRVDQETVHEMYFADHSSLDTTAILDLFQDPFELPLDVDVPFEKLDLDSLLEWIQEINAATTQLTIAFDSWELIYEYLAVRHDDPPDIKTVTNQLAVLAREENIRLMLVTETAAPSSLEYIVDGVVTLQVKEDDRGRTRRDLRLDKLRGVRIGNRLQPFTLADGQFQVITPVELLTIQTGTGNGTWDPLANSKAKFSTGIRDLDRILSGGYNRGSVVHLDLGPDLSRDAWSVLTLPTIRNFLSQEMGVAVVPPREGSPGLLHNDLNTVLSSQVFDTYCHVFETYAGPSDSADRYDQPDSTESFSEMATTTPPDDAPTATHETDGADDGSRSTDGVTGSDQPHPIDEDFESPIEGGQLAYEPYMAYVEQVREESEDPLLHVISMDTAQEAFETRLGDFANYVALHNDLTLLITKQGTELRTRADRVADMHFRLERSGDAIILYGENPLTPLLGIGISQSESIPKITLTEMV
What is the function of this protein?
May play a role in an energy requiring process such as assembly of gas vesicles in addition to a possible structural or regulatory function.
What are the official names of this protein?
Protein GvpD 1.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: Y2411_MYCTU
Sequence: MRRVSLPNQLNETRRRSPTRGERIFGGYNTSDVYAMAFDEMFDAQGIVRGPYKGIYAELAPSDASELKARADALGRAFIDQGITFSLSGQERPFPLDLVPRVISAPEWTRLERGITQRVKALECYLDDIYGDQEILRDGVIPRRLVTSCEHFHRQAVGIVPPNGVRIHVAGIDLIRDHRGDFRVLEDNLRSPSGVSYVMENRRTMARVFPNLFATHRVRAVDDYASHLLRALRNSAATNEADPTVVVLTPGVYNSAYFEHSLLARQMGVELVEGRDLFCRDNQVYMRTTEGERQVDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGNVVLSSAIGNGVGDDKLVYTYVPTMIEYYLHEKPLLANVETLRCWLDDEREEVLDRIRELVLKPVEGSGGYGIVFGPEASQAELAAVSQKIRDDPRSWIAQPMMELSTVPTRIEGTLAPRYVDLRPFAVNDGNEVWVLPGGLTRVALVEGSRVVNSSQGGGSKDTWVLAPRASAAARELGAAQIVRSLPQPLCDPTVDASGYEPHDQQPQQQQQQQQQAFH
What are the official names of this protein?
Uncharacterized protein Rv2411c.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 sll0335 and to M.tuberculosis Rv2567.
Protein: EFP_HAHCH
Sequence: MANYSTNEFKSGLKIMLDGDPCSIIENEFVKPGKGQAFNRVKFRNLKSGRVGERTFKSGDSVEGADVVDLDMEYLYTDGEFYHFMLTDGSFEQHAADVSAVGDTTKWLKEQDVYTVTLYNGAPLSVSPPNFVELEIVETDPGVRGDTAQGGSKPAKLTTGAVVAVPLFINQGEMIKVDTRSGEYVSRVKS
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_MYCA1
Sequence: MTGAVCPGSFDPVTLGHVDVFERASAQFDEVVVAILTNPAKKGMFDLDERIAMIEESTTHLSNLRVEAGQGLVVDFVRSRGMTAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLREKLSGRS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_GLUDA
Sequence: MTKVLVLYYSTYGHIETMAEAVAEGVRAAGAQADIKRVPETVPEDVARTHHFKLDQAAPIATPADLEAYDAIIVGTPTRFGRMASQMASFWDQTGGLWMKGALIGKVGAAFTSTATQHGGQETTLFSVITNLLHQGMVISGLPYNFQGQMRLDEITGGAPYGATTIAAGDGSRAVSDNERDGARFLGQHVAQIAAKLSA
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: SRP19_PYRAR
Sequence: MKKRGGRTLWLVYIDLSVPRSRGRILPRSQAVNKPTLQEMVKALEALGYKYEVYPNKKYPPLWYDDRAQGYVVVKTDEKMRIIAAKVAEKIKQIRG
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BORPA
Sequence: MSLNRQEKAVVIEEVSAQVAKAQSIVIAEYRGLDVASVTVLRKTARESGVYLRVLKNTLVRRAVAGTAFEPLSEQLTGPLIYGISADPVAAAKVLAGFAKSNDKLVIKAGSLPNSLLTQDGVKALATMPSREELLSKLLGTMQAPIAQFVRTLNEVPTKFARGLAAVRDQKAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HFQ_PECAS
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNPGGSNNYHGSNTTAQQQSQDADDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: NIKC_ECOLI
Sequence: MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGRVDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVTAPTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHAH
What is the function of this protein?
Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane.
What are the official names of this protein?
Nickel transport system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_ALKCK
Sequence: MKKIIFTGGGSAGHVTPNLAIINELNDKDWSIAYIGSYEGIERQLVEKAGIRYFGISSGKLRRYMDWKNVTDIARIANGFRQARKILKAEKPDVVFSKGGFVTVPVVAAAYTLRIPVHLHESDLTPGLANRLAKRFANTFYTSFAETAAHFPKEATTTVGSPIRRELLEGSRIQGLTITDFSRERPTLLVMGGSLGAKRINEAIRESLDTLTNTYQIIHICGKGHLDPALEGRRNYKQYEYVHDELPHFLQAADLVVTRGGSNAIFEFLALHIPMLIIPLSRAQSRGDQILNAQTFVKNGYARMLEEENLTKETLQQEVQELYNGRQTYIEAMNASQATNAVAYITEKLEQEVQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KCS10_ARATH
Sequence: MGRSNEQDLLSTEIVNRGIEPSGPNAGSPTFSVRVRRRLPDFLQSVNLKYVKLGYHYLINHAVYLATIPVLVLVFSAEVGSLSREEIWKKLWDYDLATVIGFFGVFVLTACVYFMSRPRSVYLIDFACYKPSDEHKVTKEEFIELARKSGKFDEETLGFKKRILQASGIGDETYVPRSISSSENITTMKEGREEASTVIFGALDELFEKTRVKPKDVGVLVVNCSIFNPTPSLSAMVINHYKMRGNILSYNLGGMGCSAGIIAIDLARDMLQSNPNSYAVVVSTEMVGYNWYVGSDKSMVIPNCFFRMGCSAVMLSNRRRDFRHAKYRLEHIVRTHKAADDRSFRSVYQEEDEQGFKGLKISRDLMEVGGEALKTNITTLGPLVLPFSEQLLFFAALLRRTFSPAAKTSTTTSFSTSATAKTNGIKSSSSDLSKPYIPDYKLAFEHFCFHAASKVVLEELQKNLGLSEENMEASRMTLHRFGNTSSSGIWYELAYMEAKESVRRGDRVWQIAFGSGFKCNSVVWKAMRKVKKPTRNNPWVDCINRYPVPL
What is the function of this protein?
Contributes to cuticular wax and suberin biosynthesis.  Prevents the postgenital fusion of epiderm cells in organs in contact, as well as ectopic pollen hydration and germination.  Required during ovules formation.  May regulate an epidermis-specific developmental program during gynoecial ontogeny.
What are the official names of this protein?
3-ketoacyl-CoA synthase 10, KCS-10, Protein FIDDLEHEAD, Very long-chain fatty acid condensing enzyme 10, VLCFA condensing enzyme 10.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THIC_CLOP1
Sequence: MNYTTQMDAAKKGIITKEMQVVSEKEGINIETLMNLMAEGKIVIPANKNHKSISAEGVGQGLRTKINVNLGISKDCANIELELEKVKKAIDMNAESIMDLSNYGKTYDFRKRLVEVSTAMIGTVPMYDVVGFYDKELKDITVDEFFEVVEKHAKDGVDFVTIHAGLNRETIETFRRNKRLTNIVSRGGSLLFAWMELNNRENPFYEYFDRLLDICEKYDLTLSLGDACRPGSIADATDAVQIKELITLGELTKRAWERNVQVIIEGPGHMAMNEIEANVLLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAMAASYGADFLCYVTPAEHLRLPNLEDVREGIVATKIAAHAADIAKGISGARDIDNKMSDARKRLDWDEMFSLAIDSEKAIRYRKESTPEHKDSCTMCGKMCSIRNMNKILEGKDINLLRED
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HBB4_ONCMY
Sequence: MVDWTDPERSAIVGLWGKISVDEIGPQALARLLIVSPWTQRHFSTFGNLSTPAAIMGNPAVAKHGKTVMHGLDRAVQNLDDIKNTYTALSVMHSEKLHVDPDNFRLLADCITVCVAAKLGPAVFSADTQEAFQKFLAVVVSALGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-4, Beta-4-globin, Hemoglobin beta-4 chain, Hemoglobin beta-IV chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LUXS_ECO7I
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RPOZ_SALHS
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PLR1_SCHPO
Sequence: MPIVSGFKVGPIGFGLMGLTWKPKQTPDEEAFEVMNYALSQGSNYWDAGEFYGVDPPTSNLDLLARYFEKYPENANKVFLSVKGGLDFKTLVPDGNPDFVSKSVENVIAHLRGTKKLDLFQCARVDPNVPIETTMKTLKGFVDSGKISCVGLSEVSAETIKRAHAVVPIAAVEVEYSLFSRDIETNGIMDICRKLSIPIIAYSPFCRGLLTGRIKTVEDLKEFAKSFPFLEYLDRFSPDVFAKNLPFLQAVEQLAKKFGMTMPEFSLLFIMASGNGLVIPIPGSTSVSRTKSNLNALNKSLSPEQFKEAKEVLSKYPIYGLRYNEQLAGTLSV
What is the function of this protein?
Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+).
What are the official names of this protein?
Pyridoxal reductase, PL reductase, PL-red.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B2_YEAST
Sequence: MSSAAEKKPASKAPAEKKPAAKKTSTSVDGKKRSKVRKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PYRD_BURL3
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRALGAAGRTGLACALSARVPDAPRTVMGLTFRNPVGLAAGLDKDGAAIDGLAALGFGFIEVGTVTPRAQPGNPRPRMFRLPQAEALINRMGFNNHGVDQFVKNVQAARYRGILGLNIGKNADTPIERAAEDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQQRLADLHGKLVPLALKIAPDLDDEQVKEIGDTLLRHKIEAVIATNTTLSRAAVQGLPHADEAGGLSGRPVFDASNEVIRKLHAEVGSEVPIIGVGGIFSGEDARAKLAAGAALVQLYTGFIYRGPALVSECVKAIARERTA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ZN165_HUMAN
Sequence: MATEPKKAAAQNSPEDEGLLIVKIEEEEFIHGQDTCLQRSELLKQELCRQLFRQFCYQDSPGPREALSRLRELCCQWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPESGEEAVTILEDLERGTDEAVLQVQAHEHGQEIFQKKVSPPGPALNVKLQPVETKAHFDSSEPQLLWDCDNESENSRSMPKLEIFEKIESQRIISGRISGYISEASGESQDICKSAGRVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNSNEFTHQKSCKHGTCDQSFKWNSDFINHQIIYAGEKNHQYGKSFKSPKLAKHAAVFSGDKTHQCNECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGRAFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEKPYECSECGRAFSQSSNLSQHQRIHMRENLLM
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 165, Cancer/testis antigen 53, CT53, LD65, Zinc finger and SCAN domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XKR4_RAT
Sequence: MARPPPLLVQKPSFLVEACCSPSPATHLAPYHTQPGARTPSTIQRDLLFPIPRRCHARSSPRPPALGGGPTQRLQHAARSAHPIPPSVKEIHPTFSEIPRARASDCCAAALGVQHWPARHPHPPLPSISLAVDYYLLGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSATTTASTCQQPGADCKTVVSSGSAAGEGEARPSTPQRQASNASKSNIAATNSGSNSNGATRTSGKHRSASCSFCIWLLQSLIHILQLGQVWRYLHTIYLGIRSRQSGESSRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACDDPATAFSMPPEVATSTLRSISNNRSVASDRDQKFAERDGCVPVFQVRPTAPPTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL
What is the function of this protein?
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface.  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.
What are the official names of this protein?
XK-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GWL_XENLA
Sequence: MGIVAETSQNGDTSLCSEKKFTVPQPPSIEEFGIVKPISRGAFGKVYLARRKNNSKLFAVKVVKKADMINKNMVQQVQAERDALALSKSPFIVHLYYSLQSANNIYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVAMALDYLHRHGIIHRDLKPDNMLISNKGHIKLTDFGLSKVTLKRELCMMDILTTPSMAKPKRDYSRTPGQVLSLISSLGFNTPAGGRTQGSLNQQTEGMRGNASTPLLMKKRESLVKGNKLMISCPEASLSSPSIPVKCLTPNLLKCRTQFATSSTSSQSRICLSSLESECGSPRWENCSQDAEAPPYFNSSRVKDSSSEQARSKKPTGSSASQNLKRLEFAFSPIVDRRTGKKAGFQDETGELSDTPLATLNAKGVIRKCLYENKAQEKPKDFDKTGQGELGKFTSSPDSPPWLANGSVAPIQFNDEEKTEKMGVKRNYDLVEKSPEQELLQDKKTNTDYKRGCAITDYPVSQSTGLTMEINSLFLSELRNSANKYASDRKSEDKYISAPRTLEKLDSGNPVAKNLLCELDDNCERDGEVSSTSEGEDRKERLNQDSSSTGMSVTENQIDRDLSHVDKSIKELSFEESQSENSEEITPDNKGIPFMAENDERVQSKYEPNTSILPDSLQNVLASPAPASAMTNPRRKPMVAFRSYNSPINVSNVSEPSKISMNSADKIHFSLECTGSFPMAVTPAQNKVQGLIETPYRTPKSVRRGGIQVDHERILGTPDYLAPELLLRKSHGPAVDWWALGVCLFEFLTGIPPFNDETPSQVFQNILNRDIPWPEEEEEVLSVNAQSAIEILLTIDPTKRAGLKDLKAHPLFHGMEWEELQYQPMSFIPQPDDETDTTYFEARNNAQHLKVSGFSL
What is the function of this protein?
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance.  Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of arpp19 and ensa at 'Ser-67', 2 phosphatase inhibitors that specifically inhibit the ppp2r2d (PR55-delta) subunit of PP2A.  Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high.  Following DNA damage, it is also involved in checkpoint recovery by being inhibited.
What are the official names of this protein?
Serine/threonine-protein kinase greatwall, GW, GWL, Microtubule-associated serine/threonine-protein kinase-like, MAST-L.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes.
Protein: TAF1_YEAST
Sequence: MVKQQGSGKTNLANEDEAYEAIFGGEFGSLEIGSYIGGDEGANSKDYTEHLPDAVDFEDEDELADDDDDLPEESDANLHPAMMTMGAYDDVNENGAVLGIDSNSLNMQLPEINGDLSQQFILEDDGGTPATSNALFMGMDANEIHLATETGVLDGSGANEIGHSQLSIGGVNGNDMSINGGFIMEPDMSDGKHKKATKLDLINHEKYLLKKYFPDFEKGKILKWNKLIYRRSVPYHWHSEISRVKKPFMPLNLKFKVQQDDKRLFNSRTISYVAPIYQGKNNLLQSNSSASRRGLIHVSIDELFPIKEQQKKRKIIHDEKTISEDLLIATDDWDQEKIINQGTSSTATLADSSMTPNLKFSGGYKLKSLIEDVAEDWQWDEDMIIDAKLKESKHAELNMNDEKLLLMIEKTNNLAQQKQQLDSSNLILPLNETILQQKFNLSNDDKYQILKKTHQTKVRSTISNLNIQHSQPAINLQSPFYKVAVPRYQLRHFHRENFGSHIRPGTKIVFSKLKARKRKRDKGKDVKESFSTSQDLTIGDTAPVYLMEYSEQTPVALSKFGMANKLINYYRKANEQDTLRPKLPVGETHVLGVQDKSPFWNFGFVEPGHIVPTLYNNMIRAPVFKHDISGTDFLLTKSSGFGISNRFYLRNINHLFTVGQTFPVEEIPGPNSRKVTSMKATRLKMIIYRILNHNHSKAISIDPIAKHFPDQDYGQNRQKVKEFMKYQRDGPEKGLWRLKDDEKLLDNEAVKSLITPEQISQVESMSQGLQFQEDNEAYNFDSKLKSLEENLLPWNITKNFINSTQMRAMIQIHGVGDPTGCGEGFSFLKTSMKGGFVKSGSPSSNNNSSNKKGTNTHSYNVAQQQKAYDEEIAKTWYTHTKSLSISNPFEEMTNPDEINQTNKHVKTDRDDKKILKIVRKKRDENGIIQRQTIFIRDPRVIQGYIKIKEQDKEDVNKLLEEDTSKINNLEELEKQKKLLQLELANLEKSQQRRAARQNSKRNGGATRTENSVDNGSDLAGVTDGKAARNKGKNTTRRCATCGQIGHIRTNKSCPMYSSKDNPASPK
What is the function of this protein?
Functions as a component of the DNA-binding general transcription factor complex TFIID.  Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation.  TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 1, TAFII-130, TAFII-145, TBP-associated factor 1, TBP-associated factor 145 kDa.
What is the protein family that this protein belongs to?
Belongs to the TAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_LACCB
Sequence: MALDVDGIIAQLKDASILELNDLVKSIEDEFGVKAAAPVAAGAAAGADAAAAKDTYDVELTEAGQEKVKVIKAVREITGLGLKDAKGMVDAAPKVIKEGLSEDDANKLKEQLEGVGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.