PharMolix/UniProtQA huggingface dataset:
Protein: SYE_ARCFU
Sequence: MKEVIMKYVVQNAAKYGKASEKAVMGKVMAENPELRKKAKEVLELVKECITEFEALSEEVRKELIKKYSMDSEAKRELETKKLPELEGAEKGKVVMRFAPNPNGPPTLGSARGIIVNGEYAKMYEGKYIIRFDDTDPRTKRPMIEAYEWYLEDIEWLGYKPDEVIYASRRIPIYYDYARKLIEMGKAYTCFCSQEEFKKFRDSGEECPHRNISVEDTLEVWERMLEGDYEEGEVVLRIKTDMRHKDPAIRDWVAFRIIKESHPLVGDKYVVYPTLDFESAIEDHLLGITHIIRGKDLIDSERRQRYIYEYFGWIYPITKHWGRVKIFEFGKLSTSSIKKDIERGKYEGWDDPRLPTLRAFRRRGFEPEAIKSFFLSLGVGENDVSVSLKNLYAENRKIIDRKANRYFFIWGPVKIEIVNLPEKKEVELPLNPHTGEKRRLKGERTIYVTKDDFERLKGQVVRLKDFCNVLLDEKAEFMGFELEGVKKGKNIIHWLPESEAIKGKVIGEREAEGLVERNAVRDVGKVVQFERFAFCKVESADEELVAVYTHP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_MYCTU
Sequence: MLQQIRGPADLQHLSQAQLRELAAEIREFLIHKVAATGGHLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRSQDFATLRKKGGLSGYPSRAESEHDWVESSHASAALSYADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAASRRPVIIVVNDNGRSYAPTIGGVADHLATLRLQPAYEQALETGRDLVRAVPLVGGLWFRFLHSVKAGIKDSLSPQLLFTDLGLKYVGPVDGHDERAVEVALRSARRFGAPVIVHVVTRKGMGYPPAEADQAEQMHSTVPIDPATGQATKVAGPGWTATFSDALIGYAQKRRDIVAITAAMPGPTGLTAFGQRFPDRLFDVGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVLDRAGITGSDGASHNGMWDLSMLGIVPGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDISALERRGGVDVLAAPADGLNHDVLLVAIGAFAPMALAVAKRLHNQGIGVTVIDPRWVLPVSDGVRELAVQHKLLVTLEDNGVNGGAGSAVSAALRRAEIDVPCRDVGLPQEFYEHASRSEVLADLGLTDQDVARRITGWVAALGTGVCASDAIPEHLD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RS18_PARP8
Sequence: MPRPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVEQIDYKDIDTLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALMPYTDQHKA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS7_ALKMQ
Sequence: MPRKGNVPKREVLADPIHGSMVVAKLINSVMLDGKKGTAQNIVYGAFDIIKERAEENPVEVFEKAMNNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLRWLVKYTRARGEKGMIEKLAKEIMDAANNTGSSVKKKEDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HOA2_AZOSB
Sequence: MDLRGTRITVHDMTLRDGMHPKRHLMTLEQMKTIAQGLDQAGIPLIEVTHGDGLGGSSVNYGFPAHTDEEYLGAVIPLMKQAKVSALLLPGIGTVDHLKMAHELGVNTIRVATHCTEADVSEQHISYARKLGMDTVGFLMMAHMNSPEGLVQQAKLMESYGANCIYVTDSAGHLLPDTVKARISAVRDALKPETELGFHGHHNLAMGVANSIAAIEAGATRIDAAAAGLGAGAGNTPMEVLIAVCDLMGIETGVDVFKIQDVAEDLVVPIMDFPIRIDRDALTLGYAGVYGSFLLFAKRAEKKYGVPAREILVEMGRRGMVGGQEDMIEDTAITLAKASAAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: ISPH_ACAM1
Sequence: MDTKAFKRSLHKSEQYHRKGFGHEEEVTNLLQSEYNSKLIQQIRNNGYRLQQGDVTIHLAEAFGFCWGVERAIALAYETRRQFPQERIWITNEIIHNPSVNKNLRDMKVEFIPVQPDGQKDFTVVGQNDVVILPAFGASVQEMQLLHDKGCTIMDTTCPWVSKVWTSVEKHKKGSYTSIIHGKYKHEETIATSSFAGTYLVLLNLEEAEYVADYILNPGDTPSEREQRRADFMAKFANAHSPGFDPETDLERVGIANQTTMLKGETEQIGKLFERTVMRKYGPAQVNEHFLSFNTICDATQERQDAIFQLVDEPLDLMVVIGGFNSSNTTHLQEISIDKNIPSYHIDSVDRIGPGNRVEHKPLNADLTVTDNWLPNGPLAIGVTSGASTPDKVVSDIVEKIFSIKSASAEVVGVR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PUR7_HYPNA
Sequence: MNKRRVIYEGKAKILYEGPEPGTLIQYFKDDTTAFDATKKAVLDGKGVLNNRISEFIMTHLTSVGVPNHFIRRLNMREQLVRKVDIIPLEVVVRNIAAGSLSTRLGIPEGQSLPRPLVEFYFKNDALHDPMVSEEHIAAFGWATAQEYDDIIALALRVNDFMSGLFAGAGIRLVDFKIEFGRWFENDHDMPRILLADEISPDSCRLWDAKTGEKMDKDRFRRDMGGVTEAYAEVARRLGIIRESGEETDNVIHFTGGSK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PDXY_PSEP1
Sequence: MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRIGVNAWPLNTVQFSNHTQYGQWAGEVLAPAQIPALVEGISNIGELGHCDAVLSGYLGSAEQGRAILAGVERIKAVNPKALYLCDPVMGHPEKGCIVPPEVSEFLLDEAAATADILCPNQLELDSFCGRRAQSLEDCVNMARSLLQRGPQVVLVKHLAYPGRAEEQFEMLLVTAEHSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDSWVQAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVRFEAQLLAL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: FIXA_ECO81
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAVEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASVLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: RIMP_BORAP
Sequence: MIKCFDKNNEVYNLIKNLTERLNVEILEINIFRNKNGGKIQIVLYSKNFSLGIDLMTDLHKMILLILEANLKYSFILELSTPGIDRRIKSDKEFQIFEGKKIKLMLDNEFEEGFILEAKSKSFIFKTDSKELNVFYSDVKKARLV
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_BORPA
Sequence: MNAVTDKSVADYIVADMALAGWGRRELAIAETEMPGLMAIRDEYAASQPLKGARIAGSLHMTIQTGVLIETLVALGAEVRWASCNIFSTQDHAAAAIAATGTPVFAIKGETLEEYWQYTHKIFEWPEGRHANMILDDGGDATLLLHLGARAEQDISVLAKPGSEEERVLFAAIKETLARDPKWYSTRLAQIKGVTEETTTGVHRLYQMSQKGELAFAAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKIAVVAGYGDVGKGCAQALAALRAQVWVTEIDPICALQAAMEGFKVVTMEEAAAHADIFVTATGNYHVITRQHMEAMKDQAIVCNIGHFDNEIDVAGLENCQWEEIKPQVDHVIFPDGKRIILLAKGRLVNLGCATGHPSFVMSSSFANQTIAQIELFTRNEAYTTGQVYVLPKHLDEKVARLHLKKLGAKLSTLSKQQADYIGVPVEGPFKPGHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRG_SALCH
Sequence: MHVTLVEINVHDDKVEQFIDVFRQNHLGSIKEPGNLRFDVLQDPQVPTRFYIYEAYVDEQAVAFHKTTPHYKTCVEQLEPLMTGPRTKKVFMGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDCH_BACSU
Sequence: MEWHSKFSGPNTSPGFLLWQATQSWQRKVGKALAEFDLTHVQFVLLTSCKYMIAHGETVTQKKLASFSQTNIMMVSEVVRTLEKKGFIERSKNPQDKREVLLSLTEIGGEKVTAALPIVEKIDQAFFAAAMKKENFLSGLQELLKHE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdcH.
Protein: Y2771_STRCO
Sequence: MPIPGTPSRAELAEHLVRTRIAGDVATPRENNLSHYRKLANGDRGFWLGLELGDRWSDEQDVLAVMAERVGVNDDPEHRYGQDTIDPELTISALERMAGRLRKAADGGQRVLFATGHPGGLLDVHRATAAALRDAGCEIVVIPEGLTTEEGYVQQFADVSVLEHGASLWHTHSGEPMKAILTGLEREGRPLPDLVVADHGWAGYAAQHGVDSVGYADCNDPALFLAESEGTLQVAVPLDDHVVSPRYYDPMTAYLLTEAGLK
What is the function of this protein?
Displays phosphatase activity against p-nitrophenyl phosphate (pNPP) in vitro; however, the physiological substrate is unknown.
What are the official names of this protein?
Phosphatase SCO2771.
Protein: CYB_CRAGG
Sequence: MTIMRKSHPLMKIVNHAFIDLPTPPNISGWWNFGSLLGLCLILQIFTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWLIRYLHANGASLFFMCLYIHIGRGIYYGSYLYMETWNIGILLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAMPYIGQDLVEWIWGGFSVDKATLTRFFALHFIMPFIITALVMVHLLFLHETGSNNPLGLPSDCGKVPFHPYYTTKDFMGVILLLTLFMTLVLFFPDKLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVMALAFSILVLTLLPYLHTSKQRSLSFRPLSQTLFWMLISDVIALTWIGGQPVESPYIVIGQVASVLYFSIILIFMPIAGLIENKMLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS8_PSEE4
Sequence: MSRFWSPFVKDLVPYVPGEQPKLARLVKLNTNENPYGPSPKALEAMQGELNDNLRLYPDPNSDRLKQAVAEYYGVTPAQVFVGNGSDEVLAHIFHGLFQHDRGPLLFPDVSYSFYPVYCGLYGIAFEQVELDEQFQIQVSDYSKPNAGIIFPNPNAPTGCLLPLEAVEQLLQANRDSVVVVDEAYIDFGGETAISLVDRYDNLLVTQTLSKSRSLAGLRVGLAVGHPDLIEALERIKNSFNSYPLDRMAIVGAAVAFEDREYFDETCRKVIDSREVLVEALTARGFEVLPSAANFIFARHPSQDAAGIAARLREQGVIVRHFKQGRIAQFLRITIGTPEMNQALLDAL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PRP40_YEAST
Sequence: MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNRIALTAGEKQEPGRTINEEESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVNTIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVPIKIKANTRWSDIYPHIKSDPRFLHMLGRNGSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIEKVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKKHYFWLLLQRTYTKTGKPKPSTWDLASKELGESLEYKALGDEDNIRRQIFEDFKPESSAPTAESATANLTLTASKKRHLTPAVELDY
What is the function of this protein?
Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing.  This protein is associated with snRNP U1.  Two commitment complexes, CC1 and CC2, have been defined in yeast.  CC1 is a basal complex dependent only on the 5' splice site.  CC2 is a complex of lower mobility and is dependent on a branchpoint as well as a 5' splice site region.  This protein is involved in CC2 formation where it binds to the branchpoint binding protein MSL5, bridging the U1 snRNP-associated 5' splice site and the MSL5-associated branch point 3' intron splice site.
What are the official names of this protein?
Pre-mRNA-processing protein PRP40.
What is the protein family that this protein belongs to?
Belongs to the PRPF40 family.
Protein: CMBL_XENTR
Sequence: MANEACPCPCDIGDKIEYGAKGQEVQIEHIKAYVSKPHSSTDKAVIVVQDIFGWQLPNTRFMADLLTAHGYITICPDFFVGQEPWKPSNDRSTFTEWLQTRQATKVEKEINVVLKYLKEQCHVKKIGVIGFCWGGVVTHHLMLKYPELKAGVSFYGIIRDVEDRYNLLNPTLFIFAEMDHVIPLEQVSLLEEKLKVHSKVDFQVKVFPKQTHGFVHRKNEDINPEDKPFIEEARKNMLEWLHKYIN
What is the function of this protein?
Cysteine hydrolase.
What are the official names of this protein?
Carboxymethylenebutenolidase homolog.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CSLA2_ORYSJ
Sequence: MSTNGGAPSQKRSWLPSRPLLTTTTQTYPPPLLPFKKLHAPPTAARRSLPPAASKPMASSSSSSLPAAWAAAVRAWAVAPALRAAVWACLAMSAMLVAEAAWMGLASLAAAAARRLRGYGYRWEPMAAPPDVEAPAPAPAEFPMVLVQIPMYNEKEVYKLSIGAACALTWPPDRIIIQVLDDSTDPFVKELVELECKEWASKKINIKYEVRNNRKGYKAGALRKGMEHTYAQLCDFVAIFDADFEPESDFLLKTMPYLLHNPKIALVQTRWEFVNYNVCLMTRIQKMSLDYHFKVEQESGSFMHAFFGFNGTAGVWRVSAINQSGGWKDRTTVEDMDLAVRASLKGWEFLYVGDIRVKSELPSTFQAYRHQQHRWTCGAANLFRKMAWEIITNKEVSMWKKYHLLYSFFFVRRAIAPILTFLFYCIVIPLSAMVPEVTIPVWGLVYIPTAITIMNAIRNPGSVHLMPFWILFENVMAMHRMRAALSGLLETARANDWVVTEKVGDQVKDELDVPLLEPLKPTECAERIYIPELLLALYLLICASYDFVLGNHKYYIYIYLQAVAFTVMGFGFVGTRTPCS
What is the function of this protein?
Probable mannan synthase which consists of a 4-beta-mannosyltransferase activity on mannan using GDP-mannose.  The beta-1,4-mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase.  Galactomannan is a noncellulosic polysaccharides of plant cell wall.
What are the official names of this protein?
Probable glucomannan 4-beta-mannosyltransferase 2, Cellulose synthase-like protein A2, OsCslA2, Glucomannan synthase, Mannan synthase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RL13_LISMH
Sequence: MRTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDTGDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKLLELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQQPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DNJA1_MOUSE
Sequence: MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLADSKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPRGGVQCQTS
What is the function of this protein?
Co-chaperone for HSPA8/Hsc70.  Plays a role in protein transport into mitochondria via its role as co-chaperone.  Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro).  Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (By similarity).  Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis.
What are the official names of this protein?
DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, Heat shock 40 kDa protein 4, Heat shock protein J2, HSJ-2.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cytoplasm. Microsome. Mitochondrion. Nucleus. Cytoplasm, perinuclear region. Note=Primarily cytoplasmic and associated with microsomes. A minor proportion is associated with nuclei and mitochondria (By similarity).
Protein: Y1010_STRR6
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein spr1010.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PSBA_ARATH
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KN7M_ARATH
Sequence: MASSSSRTRSRSPFSHRRPPSPYSSASSTSSSLINNRLLPRSSSTPTSTVYNSGGVTGSRSMSITRTISDSGPIGGSGTYGAQSYPSEGLIGESGQTITSERDSISVTVRFRPMSEREYQRGDEIVWYPDADKMVRNEYNPLTAYAFDKVFGPQSTTPEVYDVAAKPVVKAAMEGVNGTVFAYGVTSSGKTHTMHGDQDFPGIIPLAIKDVFSIIQETTGREFLLRVSYLEIYNEVINDLLDPTGQNLRIREDSQGTYVEGIKEEVVLSPGHALSFIAAGEEHRHVGSNNFNLMSSRSHTIFTLMIESSAHGDQYDGVIFSQLNLIDLAGSESSKTETTGLRRKEGAYINKSLLTLGTVIGKLTEGKTTHVPFRDSKLTRLLQSSLSGHGHVSLICTVTPASSSTEETHNTLKFASRAKRIEINASRNKIIDEKSLIKKYQKEISTLKVELDQLRRGVLVGVSHEELLSLKQQLQEGQVKMQSRLEEEEEAKAALMSRIQKLTKLILVSTKNSIPGYLGDTPAHSRSISAGKDDKLDSLLLDSDNLASPSSTLSLASDARRSSSKFKDENSPVGSRAELTQGVMTPDEMDLLVEQVKMLAGEIAFGTSTLKRLVDQSMNDPENSKTQIQNLENDIQEKQRQMKSLEQRITESGEASIANASSIEMQEKVMRLMTQCNEKSFELEIISADNRILQEQLQTKCTENNELHEKVHLLEQRLSSQKATLSCCDVVTEEYVDELKKKVQSQEIENEKLKLEHVQSVEEKSGLRVQNQKLAEEASYAKELASAAAIELKNLADEVTKLSLQNAKLEKELVAARDLAAAAQKRNNNSMNSAANRNGTRPGRKARISDSWNLNQENLTMELQARKQREAVLEAALAEKEYIEEEFRKKAEEAKRREEALENDLANMWVLVAKLKKANSGALSIQKSDEAEPAKEDEVTELDNKNEQNAILKERQLVNGHEEVIVAKAEETPKEEPLVARLKARMQEMKEKEMKSQAAAAANADANSHICKVCFESPTATILLPCRHFCLCKSCSLACSECPICRTKISDRLFAFPS
What are the official names of this protein?
Kinesin-like protein KIN-7M, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GBA1_PONAB
Sequence: MEFSSPSREECPKPSGRVNIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSLDPLTFPALGTFSRYESTRSGRRMELSTGTIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLARRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHHLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDTVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ
What is the function of this protein?
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramides/GlcCers (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) into free ceramides (such as N-acylsphing-4-enine) and glucose.  Plays a central role in the degradation of complex lipids and the turnover of cellular membranes.  Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation.  Catalyzes the glucosylation of cholesterol, through a transglucosylation reaction where glucose is transferred from GlcCer to cholesterol.  GlcCer containing mono-unsaturated fatty acids (such as beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4-enine) are preferred as glucose donors for cholesterol glucosylation when compared with GlcCer containing same chain length of saturated fatty acids (such as beta-D-glucosyl-N-octadecanoyl-sphing-4-enine).  Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl 3-beta-D-glucoside to ceramide.  Can also hydrolyze cholesteryl 3-beta-D-glucoside producing glucose and cholesterol.  Catalyzes the hydrolysis of galactosylceramides/GalCers (such as beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine), as well as the transfer of galactose between GalCers and cholesterol in vitro, but with lower activity than with GlcCers.  Contrary to GlcCer and GalCer, xylosylceramide/XylCer (such as beta-D-xyosyl-(1<->1')-N-acylsphing-4-enine) is not a good substrate for hydrolysis, however it is a good xylose donor for transxylosylation activity to form cholesteryl 3-beta-D-xyloside.
What are the official names of this protein?
Lysosomal acid glucosylceramidase, Acid beta-glucosidase, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, SGTase, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Lysosomal cholesterol glycosyltransferase, Lysosomal galactosylceramidase, Lysosomal glycosylceramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
Protein: TF2B_KLULA
Sequence: MSLPAAASANVAVSSRRRGPNLNIVISCPECKVYPPKVVERFSEGDIVCALCGLVLSDRIVDTRSEWRTFSNDDQNGDDPSRVGEASNPLLDGNHLTTRIGQAQGSDARVTRDLNRAQSKSIVDKKDNELQAAYAKITMMCDAAELPKIVKDCAKEAYKLCFEERVLKGKSQESIMASVILVGCRRAEVGRSFKEILSLTNVRKKEIGKTFTIIKNILREKNDRGFANIDTSNITTGQTSAETFIPRFCSHLGLSVQVANAAEYIAKHSKDVNVLAGRSPITIAAAAIYMATLLFKLNISPTRISQTLQVTEGTVKGGYKALYEHKEKVVDPQLIESGVVKWDNLPRVSNDKSEKAN
What is the function of this protein?
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.