PharMolix/UniProtQA huggingface dataset:
Protein: MLCG_PENCI
Sequence: MGVAMTEGSFIPPVKQTILTVNDKDEVVIWDDAPTPKLPADQVYVRIHAVAVNPSDTKMRGDFATPFACLGTDYAGTVVAVGSEITHVKVGDRVFGAQNEMCPRTPEQGAFSQYTITRGRIWAKIPDSMTWEAAASLPAGISTTGLAMKLLGMPLPYSETKPSKKTYVLIYGGSTATATIAMQFMRLSGYTPIATCSHKNFDLAKKNGAEEVFDYRDADCAQKIRDYTRNNLAYALDCIINVESTSTCYKAIGRAGGRYVALNPFPEHAATRKMVTSDWTLGPTIFGEGSTWPAPYGCEASEEVRLFGTELWQVASRLVEEDKLYHHPLRVIDGGLEQVKQGMETVRNGELSGEKIVVRFSV
What is the function of this protein?
Dehydrogenase; part of the gene cluster that mediates the biosynthesis of compactin, also known as mevastatin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:12172803).  Compactin biosynthesis is performed in two stages (PubMed:12172803).  The first stage is catalyzed by the nonaketide synthase mlcA, which belongs to type I polyketide synthases and catalyzes the iterative nine-step formation of the polyketide (PubMed:12172803).  This PKS stage is completed by the action of dehydrogenase mlcG, which catalyzes the NADPH-dependent reduction of the unsaturated tetra-, penta- and heptaketide intermediates that arise during the mlcA-mediated biosynthesis of the nonaketide chain and leads to dihydro-ML-236C carboxylate (PubMed:12172803).  Covalently bound dihydro-ML-236C carboxylate is released from mlcA by the mlcF esterase (PubMed:12172803).  Conversion of dihydro-ML-236C carboxylate into ML-236A carboxylate is subsequently performed with the participation of molecular oxygen and P450 monoogygenase mlcC (PubMed:12172803).  Finally, mlcH performs the conversion of ML-236A carboxylate to ML-236B/compactin carboxylate through the addition of the side-chain diketide moiety produced by the diketide synthase mlcB (PubMed:12172803).
What are the official names of this protein?
Compactin nonaketide synthase, enoyl reductase component, Compactin biosynthesis protein G, Compactin nonaketide synthase mlcG, Enoyl reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: COPI_PSEAE
Sequence: MFPRRLLPASLIVLGVLFGASAQASPAHGQAFGKPAQAAQASRSIEVVLGDMYFKPRAIEVKAGETVRFVLKNEGKLLHEFNLGDAAMHAEHQKEMLEMQQSGMLTPTGMASMDHSQMGHGMADMDHGRMMKHDDPNSVLVEPGKSAELTWTFTKATRLEFACNIPGHYQAGMVGQLTVQP
What is the function of this protein?
Involved in copper tolerance.
What are the official names of this protein?
Copper-resistant cuproprotein CopI.
What is the protein family that this protein belongs to?
Belongs to the CopI family.
Protein: DUT_BURO0
Sequence: MKLDLKILDARMRDYLPAYATTGSAGLDLRACLDAPVTLQPGETTLVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSTWNRGQTAFVLNPFERLAQLVIVPVVQAQFNIVDEFTESDRGEGGFGSTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PSRP_CUPNH
Sequence: MFIVSDGTGITAETFSHSILAQFEMRFRKVRMPFVDTPEKAHIAVGKINEAFHNEGVPPIVFTTLVNQEANKALRRAKAMILDMFQTFIEPLEKELGLKSTHAIGRFHQNADTEAYKNRIEAINFSLAHDDGQSHKNLEEADVILVGVSRSGKTPTSLYLAMQYGLKAANYPLIPDDFERGRLPSALYAFKPKIFGLSIDPQRLTEIRNERRPGSKYAALENCRYEVNEAEAMMRREGIKWLSSTHKSIEEIATTILQEIKVDRDNY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RS18_BURVG
Sequence: MARPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVDQIDYKDTETLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALLPYTDQHKA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: OMT7_DICDI
Sequence: MESNDLNKESLENWNESWDLVMTFGMGHLTSKLFNILMNNSIFDMINESPKHYKEIAKIINFNEFSCYRLLRYFVPYGLFEENNEIFSITNKSKKLIKSGGIYNLCTFFSSNDYFKLYSTIPESFEQNKNLGPSSFGFDDFWDIVKTNEHFKYSFNQEMREFSNLSIPTIIKNTDFSSFNTVVDVGGSHGRIVGELVKKYENLNGIVFDLETVINSSIEKIKHPRIEYVSGSFFESVPSADCYVLKNILHDWDDEKCLEILKTISKSMKENSKIFIFDEIIDPNDYRKLSLFLDVTVFHFFNSRERSLNDWKQLCDKSDFKIDSINNVTQPQLLILSKK
What are the official names of this protein?
O-methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: HIS7_CAUVN
Sequence: MARTAEVVRETKETQIRVWIDLDGTGVSTISTGIGFYDHMLESFARHGGFDLKVETKGDLHIDMHHTVEDTGIVLGQAIHKALDGFKGIRRFGSAYIPMDETLTRCAIDLSNRPYLIWKVEFKRPKVGEMDTELFKEFHHAFAMNSGACIHLETLYGDNTHHVAESGFKALARALRQAVEIDPKTGGQAPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCZC_BACSU
Sequence: MELAGFMLRACALLLDVIIAAAVILAAGFTFGDGSAGVIIVAILMLIVYPLLMPLTNWKGTLGKKIIGLQIVRDETYKKISFPQAIVRYLIAWVHVFSRLIYLTAAFTKKKQTVHDMAAKTIVLKAE
What are the official names of this protein?
Uncharacterized protein YczC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOC2_SYNPW
Sequence: MTSTPSKSRKSSKGSKAAKAAASAPETRPLAKTPPPFRNRVVDKKGLKQLVAWAYKHHGTAATSAMADQLKDLGFRYATQAAVSISVNDLKVPEAKQNLLGQAEELITATEESYRLGVITEVERHTKVIDTWTETNERLVDAVKKNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREDDCGTSRCILVKAEDGKYGNRLVGRLTADQVVGADGEVLAERNTEIDPPLSKRFEKAAVQAVSVRSPLTCEANRSVCRKCYGWALAHNELVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAETGVVRSKLEGTVEFGAKARVRPYRTPHGVNAQQAEVDFNLTIQPSGKGKPQKIEITNGSLLFVDNGQAIDADVTVAQIAAGAVKKSVEKATKDVICDLAGQVSYDPSIQPREVTDRQGNITHKAQRLGRMWVLAGDVYNLPPNARPVVTAGATVTEGQVLAEASQASEYGGAIRLREALGDSREVQIVTTAMTLRDFKLQGESTHAGEIWNLEAKDGTRYRLNTIPGSKIGSGEVVAELNDDRFRTQTGGLVRFAPGLAIKKARSAKNGYEVNKGGTLLWIPQETHEINKDISLLMITDGQWIEAGTEVVKDIFSQTAGIVTVTQKNDILREIIVRSGSFHLCTEKKALERFQGDGVMVNPGEPIAKGISTETMVYVQTVETPEGSGLLLRPVEEYTIPNEAQLPDLGHVKQPNGPHLGLKASQRLAFKDNELVKSVEGVELLRTQLMLETFDTTPQMTVDVEAVPDKRAKTIERLQLVILESILVRRDTISDSSHGSTHTELQVEDGQSIKAGEVIATTQILCKQEGVAQMPEATADEPVRRLIVERPEDTLTISTNSQPVVTVGQRIVDGEELAAGQPSDCCGEVEKVDSTSVTLRLGRPYMVSPDSLLHVRDGDLVQRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRESAILCKKPGTVEIKQGEDDENTTVTVIEADDAVSEYPILLGRNVMVSDSQQVTAGELLTDGPINPHELLECFFEDLRSRKPLMDAAQEAIAKLQHRLVTEVQNVYKSQGVSIDDKHIEVIVRQMTSKVRVEDAGDTTLLPGELIELRQVEDTNQAMSITGGAPAEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFEEELKAEAGPHPDILAEDPAGYRRMQNLRPDYTVDMPAAPAGDATAVLDDPSDADMEATRSRHGIEAGSNFAAFARPDADNELKEEQVVDAEAVEGLQEEGLLSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: SFSA_SYNC1
Sequence: MKLPAPLIEGRLVRRYKRFLADVELADGSLVTAHTPNTGSMLQCAVPGHRVLISRSDNPKRKLAYTLELIEVAGFWVDTHTHRTNRVAEEALRGGAVLEFTGWQVTPEHTYGDSRIDFLLQQNDRQALVEVKNVTLLCDGQCACFPDAVTTRGQKHLRTLMDARRAGMRAAILFVVQRGEATAFRPADTIDPEYGRLLRQAVSEGVEALAYRTRISPTQTFIDRRLPVWLD
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.