PharMolix/UniProtQA huggingface dataset:
Protein: HEM0_DANRE
Sequence: MSAFLHHCPFLKSSPGPSARKVATYLNLADRCPIIVRQISAKAAQSSEQNGLLPHKEPKRQLATTATQVAVSMSQSCPFVSSKIGLVKASPQVQEDVQPNLENQDTSGLISSLFSGLQSHQSTGPTHLLQDNFNRPTFSYDEFFTQKIVEKKKDHTYRIFKTVNRFAEVFPFAEDYSIAGRLGSQVSVWCSNDYLGMSRHPRVVKAIGDALKKHGAGAGGTRNISGTSNYHVALENELARLHQKDGALVFSSCFVANDSTLFTLAKMLPGCEIYSDMGNHASMIQGIRNSGAKRFIFRHNDASHLEELLSRSDPLTPKIVAFETVHSMDGAICPLEELCDVAHKYGALTFVDEVHAVGLYGAHGAGVGERDNVMHKIDIVSGTLGKAFGCVGGYIASTAALVDTVRSFAAGFIFTTSLPPMVLAGALESVRVLKSDEGQALRRAHQRNVKHMRQLLLDAGLPVVNCPSHIIPIRVGNAAKNSEVCDILLEKHNIYVQAINYPTVPRGEELLRLAPSPFHNPIMMNYFAEKLLDVWQEVGLPLNGPAQASCTFCDRPLHFDLMSEWEKSYFGNMEPRYITVAAQ
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (By similarity).  Contributes significantly to heme formation during erythropoiesis (By similarity).
What are the official names of this protein?
5-aminolevulinate synthase, erythroid-specific, mitochondrial, ALAS-E, 5-aminolevulinic acid synthase 2, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: MSOX_STRAW
Sequence: MSPTYDVIVIGLGGMGSAAAHHLSARGARVLGLEKFGPVHNRGSSHGGSRITRQSYFEDPAYVPLLLRSYELYEEVERSTGREVATLSGGVMVGRPDSLTVAGSLRSATQWDLPHEMLDAKEIRRRFPTLNPSNDEVALYEKKAGLVRPENMVAAHLQLATRQGAELHFEEPMTRWEPYRDGVRVHTAENTYTAGQLVICPGAWAPQLLTDLGVPFTIERQVMYWFQPRHGVGPFRPENHPIYIWEDAEGVQVYGFPSIDGPDLGAKVAFFRKGVVCTPETIDRTVHDHEVQAMADHMSRCIPDLPGTFLKAATCMYSNTPDEHFVIARHPAHPDSVTVACGFSGHGFKFVPVVGEIVADLALTGTTAHPIGLFDPRRLAAAPA
What is the function of this protein?
Catalyzes the oxidative demethylation of sarcosine.
What are the official names of this protein?
Monomeric sarcosine oxidase, MSOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MSOX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SHEAM
Sequence: MMSVSLAWPAPAKLNLFLHINGRLPNGYHELQTLFQFIDYGDWLDFKITATPELKLHSNLSQVVPDSDNLILKAAKSLQSVTGCIQGAEIWLDKRLPMGGGLGGGSSDAATTLVALNALWQLGLDKKALMDIGLTLGADVPVFINGIAAFAEGVGEKLQPVDVAEPWYLVLIPDAHVSTADVFQHPDLPRNTPKLDMSSLSPERWSNDCQALVSAKYPQVANALSWLVEYAPSRMTGTGACVFGEFGSQQAALEALAKKPAEMQGFVAKGLNRSPLELRLAQL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MEP_COLGM
Sequence: MYRSMKSLALLGLLGPTSQVFAHPATGHAHNIGRRGVDIEAFRLPQVGSYTNATEIETTPPIALLKRESYVETATELVKKLAPNSEFRLVGDHYVGTNGIGHVNFKQTVHGLDIDNGDFNVNIGKDGKVFSYGNNFFKGEAPEASPLKKRDFKDPVSALKGAKDVLQLPVEAASASAEPKEGTEVYSIKGTSGTVSDPEARLVYFVKADGSLALSWRVETDITENWLLTYVDAETGTDVHGVVDYVSDLANYRVYPWGVNDPTEGDRVLVTDPWDISASPLTWQSDGTTNYTTTRGNNGIAQSNPSGGTAYLNNYRPTSAARNFDYQYTTSLTTPSSYIDASIAQLYYTANHYHDLLYTLGFTESAGNFQINNNGKGGVGNDFVVLFAQDGSGTNNANFLTPPDGSNGRMRMYLWTMSTPRRDCSFEAGVVIHEYTHGLSTRLTGGPANSNCLNALESGGMGEGWGDFFATAIRLKPTDTRATDYSMGAWVYNNPAGIRSVLYSTSMTTTPNTYSTINGVSSVHRIGETWATTLYEVLWNLIDKHGKNDGPRPEFDSNGVPTDGKYLTLKLVLDGMALQPCSPNFIQARDAILDADKALTGGDNLCELWTAFAKRGLGSNAVYSSSNRRDGFNVPAGVC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloproteinase mep, Elastinolytic metalloproteinase mep, Fungalysin mep.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_STRS7
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIKEHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TPX2_HUMAN
Sequence: MSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPVDNTYYKEAEKENLVEQSIPSNACSSLEVEAAISRKTPAQPQRRSLRLSAQKDLEQKEKHHVKMKAKRCATPVIIDEILPSKKMKVSNNKKKPEEEGSAHQDTAEKNASSPEKAKGRHTVPCMPPAKQKFLKSTEEQELEKSMKMQQEVVEMRKKNEEFKKLALAGIGQPVKKSVSQVTKSVDFHFRTDERIKQHPKNQEEYKEVNFTSELRKHPSSPARVTKGCTIVKPFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKDDINLLPSKSSVTKICRDPQTPVLQTKHRARAVTCKSTAELEAEELEKLQQYKFKARELDPRILEGGPILPKKPPVKPPTEPIGFDLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLPITVPKSPAFALKNRIRMPTKEDEEEDEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSFDSRDKERQLQKEKKIKELQKGEVPKFKALPLPHFDTINLPEKKVKNVTQIEPFCLETDRRGALKAQTWKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKSVAEGLSGSLVQEPFQLATEKRAKERQELEKRMAEVEAQKAQQLEEARLQEEEQKKEELARLRRELVHKANPIRKYQGLEIKSSDQPLTVPVSPKFSTRFHC
What is the function of this protein?
Spindle assembly factor required for normal assembly of mitotic spindles.  Required for normal assembly of microtubules during apoptosis.  Required for chromatin and/or kinetochore dependent microtubule nucleation.  Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764).  Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764).  TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940).  At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
What are the official names of this protein?
Targeting protein for Xklp2, Differentially expressed in cancerous and non-cancerous lung cells 2, DIL-2, Hepatocellular carcinoma-associated antigen 519, Hepatocellular carcinoma-associated antigen 90, Protein fls353, Restricted expression proliferation-associated protein 100, p100.
What is the protein family that this protein belongs to?
Belongs to the TPX2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
Protein: HCHA_ECOLU
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_SHIB3
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAILHGLAIAAAIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_CLOBJ
Sequence: MDFEAVIGLEVHAELSTNTKIYCGCTTEFGGQPNTHVCPICLGLPGSLPQLNKRVVEYGIKAGLALNCSINKVCRMDRKNYFYPDCPKNYQITQDEVPICRDGYIEIELENGEKKKIGIERIHMEEDAGKLLHTNAGTLVDYNRAGVPLIEIVSRPDIRTPEEATKYLEKLKSILSSIEVSDCKMEQGSLRCDGNISVMPKGSEKFGVRSEIKNMNSFKALEKALSYEYDRHVEAVTKGEILEQETRRWDEANSVTVLMRSKEKANDYRYFPEGDLVTLNISDEWIEEVRKTIPELPHEKAERFVNEFRIPKYDAMVLTLTMDMAKFFEETTLKSEDAKATSNWLMGDISRLMNEKTIEVKDLKFNPEQLAELIKLINAGTISNNIGKKVLDDMFKSGKSPKDIVEEKGLVQNNDEGAILEVVKKIIENNPQSIEDFKNGKKRALGFLVGLVMKETKGKANPQIVNKLVSEEANKM
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SCN4B_MOUSE
Sequence: MSRAGNRGNTQARWLGTGLLGLFLLPMYLSLEVSVGKATTIYAINGSSILLPCTFSSCYGFENLYFKWSYNNSETSRILIDGIVKNDKSDPKVRVKDDDRITLEGSTKEKTNNISILLSDLEFSDTGRYTCFVRNPKEKDLNNSATIFLQVVDKLEKVDNTVTLIILAVVGGVIGLLVCILLLKKLITFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPTKV
What is the function of this protein?
Modulates channel gating kinetics.  Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation.  Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity).
What are the official names of this protein?
Sodium channel subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LOVG_DROME
Sequence: MTNNDAAVEAAGSSRASSSKQQLKLEITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKYAEFVFITAPHVAKALESAAEPVPEQRSWWANKDDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLICGLAKKKLTSIRPEFAVLASGFLSGSLVHMSAYEEAISIPTLHIYGQTDEIIPKEMSESLAARFKNAEVLEHSGGHYFPATAQQKQTFINFFQDRLQEYLEHEELQQSGNASFVDSGAEDDNDAEVAAMTAELDESD
What are the official names of this protein?
Esterase CG5412.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: NAGZ_XYLF2
Sequence: MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVDQEGGRVQRFHEGYSALPPLQGIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPVTLKHFPGHGSVLEDTHVDLAVDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGFRGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAALIGLIGRGVLGWDGLLADVRYGSIQSHLFERFGTST
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_BURMA
Sequence: MNDSVKTSLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYGKYVVRSKKYHAHDEANTYNEGDLVEIQETRPVSKTKAWAVSRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS13_STAAT
Sequence: MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ILVC_CAMJJ
Sequence: MAITVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVIIGLREGSVSAVKAKNAGFEVMSVSEASKTADVVMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVAPKGIDVIMIAPKAPGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDYITGPKIVTEETKKAMKGVLKDIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWISAKKLVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YQGF_STRPF
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTRLEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_GEOSM
Sequence: MANVVVIGAQWGDEGKGKVVDIYTEFADDVVRYQGGNNAGHTLVVGDEKVILHLIPSGILHEGKRCVIGNGVVLDPEVFIMEITKLKANGYLKDDKMLLLSEALHIIMPYHKRIDIAREKKSGSKKIGTTGRGIGPAYEDKIGRRGIRLMDLLDEKAFTRKVKEVLEEKNLILTQLLGEQPFTFEEIYEEYMKYAETLRKYAADTSLILHQEIKAGKSLLFEGAQGTLLDVDHGTYPYVTSSSTCSGGACTGSGVSPREIHEVIGISKAYATRVGSGPFPTELEDETGEQLRQAGREFGSTTGRPRRTGWYDALVARYAVRINGLSGIAITKLDVLSGQETVKVCTAYNYKGQVLTEVPASLEVMELCTPIYEELPGWNEDITGAKSMAELPKNARDYVARVEELSGAPVVLVSVGPRRDETIVLRNPFQLD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_POLSJ
Sequence: MSKLTKRQKTIGDKIDSNKLYALSDAIGLVKEFAVAKFDESIDVAVQLGIDAKKSDQVVRGAVVLPNGTGKTKRVAVFAQGAKAEEAKAAGADIVGMDDLAAEIKAGKMDFDVVIASPDAMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIVHGTIGRRSFDTAKLQGNLAALIDALQKAKPASSKGVYLKKVAVSSTMGVGVRVDTQTIAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LEXA_BRUAB
Sequence: MLTRKQHELLLFIHERLKETGIPPSFDEMKEALDLASKSGIHRLITALEERGFIRRLPNRARALEVLRLPDSIAPGLSPQKKFAPSVIEGSLGKVASVQPVRPAPAPQNSEAPATVSVPVMGRIAAGVPISAIQNQTHMLSLPPEMIGAGEHYALEVKGDSMIDAGIFDGDTVIIKRGDTANPGEIVVALVDEEEATLKRFRREGASIALEAANPAYETRIFGPDRVHVQGKLVGLIRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ATPA_STAAC
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ROLC3_PANGI
Sequence: MAEDDLCSLFFKLKVEDVTSSDELARHMKNASNERKPLIEPGENQSMDIDEEGGSVGHGLLYLYVDCPTMMLCFYGGSLPYNWMQGALLTNLPPYQHDVTLDEVNRGLRQASGFFGYADPMRSAYFAAFSFPERVIKLNEQMELTSTKGKCLTFDPYASTQLRFEPGELVRHGECKFAIG
What is the function of this protein?
Hydrolyzes cytokinin glucosides thus liberating free cytokinins.
What are the official names of this protein?
Cytokinin-beta-glucosidase 3, Protein ROL C 3, rolC3-Pg.
Protein: LEXA1_PSEPK
Sequence: MLKLTPRQAEILAFIKRCLEDNGFPPTRAEIAQELGFKSPNAAEEHLKALARKGAIEMTPGASRGIRIPGLEAKAEEAGLPIIGRVAAGAPILAEQHIEQSCNINPAFFHPQADYLLRVHGMSMKDVGIFDGDLLAVHTCREARNGQIVVARIGDEVTVKRFKREGSKVWLLAENPEFAPIEVDLKEQELVIEGLSVGVIRR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y993_CAMJE
Sequence: MKELEKYSTCLKRIDEFSQNLGIKKKDRTIFKMKQSENENEKCLVLENGSFDSPEPWFVIDENDEIHTLLSLQSLKNILESLKQSQKENFELRLEKAIYQQIPVDFNDVWTVAMDEIKQKAQNGTMEVSIDLEKLISKIKQEHPNLFVDMQAMIERVNQNERL
What are the official names of this protein?
UPF0763 protein Cj0993c.
What is the protein family that this protein belongs to?
Belongs to the UPF0763 family.
Protein: EX7S_BACC1
Sequence: MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKNVQEQMAVILGEDGVLEPFTALGDEA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPT_CEREL
Sequence: MSALPVVVTLLLCGQLLAVEISSEATADSCPKAPEIANSHVEYSVRYQCDKYYKLRAGDGVYTFNNKQWINKDIGQQLPECEDASCPEPPKIENGYVEHSIRFQCKTYYKLRSAGDGVYTFNSKKQWINKNVGQQLPECEAVCGKPKHPVDQVQRIIGGSLDAKGSFPWQAKMVSHHNLISGATLINERWLLTTAKNLYLGHTSDKKAKDIAPTLRLYVGKNQPVEVEKVVLHPDRSKVDIGLIKLRQKVPVNEKVMPICLPSKDYVAVGRVGYVSGWGRNANFNFTEHLKYIMLPVADQDKCVEHYENSTVPENKTDKSPVGVQPILNKNTFCVGLSKYQEDTCYGDAGSAFVVHDQEDDTWYAAGILSFDKSCAVAEYGVYVKVTSILDWVRKTIADN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: FOMT3_OCIBA
Sequence: MAVDKEVQLHAQAWEHALSYINSTALSAAVELEIPDILEDHGGLMSLSELSAASGCPREPLYRLMRFLIFHGIFTKSDDCYAQSPLSRLFTRENLGPYMLMQATPVTRSPAGLSGEALKTGTSLYLKSIRGEDSWSDPAYGYHMKAFTNAMIAHARLTAAAIVSNYPAAFDGLRSVVDVGGRHGTAIGRLVEAFPWVRGIAFDLPEIVADAPPRKGVDFVGGDMFESVPKADAVMLMWILHDWSDDKCIEILKKCKEAIPASTGKVMIVDAIINEDGEGDEFSGARLSLDMIMLAVMAQGKERTYKEWVHLLNEAGFSKHTVKNIKSIESVIEAYP
What is the function of this protein?
Flavonoid 4'-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as nevadensin and salvigenin, aroma compounds which contribute to the flavor of sweet basil, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:22923679).  Catalyzes S-adenosylmethionine-dependent regioselective 4'-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including scutellarein-7-methyl ether (SCU7Me) and cirsimaritin (CIRM), and, with a lower efficiency, hispidulin, ladanein (LAD), cirsioliol (CIRL) and genkwanin (GENK) (PubMed:22923679).
What are the official names of this protein?
Flavonoid 4'-O-methyltransferase 3, ObFOMT3, Cirsiliol 4'-O-methyltransferase, Cirsimaritin 4'-O-methyltransferase, Genkwanin 4'-O-methyltransferase, Scutellarein-7-methyl ether 4'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.