PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_PROM5
Sequence: MKKQQSSNESFDVIVIGGGHAGCEAAITTAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADETAIQKRILNASRGPAVWALRAQTDKREYSKRMIEILQNTDNLSLKEAMITELLIKEVETFTKNSKNTTKQIKGVKTFFGTCYSAKSIIITAGTFLEGRIWIGNKSMSAGRSGEQAAQGLTESLHSLGIKTERLKTGTPARVDKKSISFDALDIQPSTASDKYFSFDPKIKNDMPQICCHITRTTQKTHELIRNNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKNSHQIFLEPEGINTPEIYVQGFSTGLPENIQLELLRTLPGLNKCKMLRPAYAVEYEYIPATQLKLSLETIEIDNLFSAGQINGTTGYEEAAAQGLVAGINATRKLNMKDPIIFSRESSYIGTMINDLITRDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGFEIGLIDERRWFAHKEKMKLLKEENSRLENTRLKCTDEIARNIELESGSKIKGSTTLKDLLKRPNVHYSDFIKYDLANKSLPIAVMEGVEIDIKYEGYLKRQQNNIDQINRQSLKSLPIEINYDLIDTLSLEARENLNKIKPTNFGDASKIPGVSKADLTALLVWLKIKEIKKEKTNSFVEKKLSS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_VIBC3
Sequence: MTPFAYKLPIRALWLGLLSLLLVGCQIDSEPKSELEKIRERGVLRVGTLNNPLSYYIGPDGPTGLDYELAREFAKELGVKLEMKPAYRLSSLFPALKNGEVDIIAAGLSQSEERLKDFRAGPAYYYVSQQVVYKKGDWRPRSFKQLVERQQTLLKDNPELAFFSVVDDSHFEHTLLAKQQKYPDFQFHVDSNSDVNDLLKKVSQGELLFTMADSVEVSLSQRIYPELAAAFELTEDQPISWFIRRSDDESLYALMIEFFGNLKQSGYLASLEEKYIGHIGAFDYVDTRAFIRALDTRLPRWTPLFQKYSAEFDWRLVAALAYQESHWNPYAKSPTGVRGLMMLTLPTARSVGVSDRLDPEQSIRGGVEYLRRMMERVPDSISEHEKIWFALASYNIGYGHMMDARRLTKSQGADPDSWADVKDRLPQLQQKKYFTQTRYGYARGDEARNYVENIRRYYQSIIGHLEQRQLATGDESIEDLTVIALDEEFFNEEANREILDEEAEALESESLENSESSAEPSAKPSTESKN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: MNMA_NITSB
Sequence: MSKKIVVAMSGGVDSSYTANLLQSRGYEVIGVYMKFHPREEYHQKNIANIQKVAKHLGIEYHVLDRTKEFQERVYQPFVDSYVAGLTPNPCAMCNRVMKFTELIEFADELGVDNVATGHYAKTDGQFIYEATDKSKDQSYFLFNLKKEFLPRIIFPLGDWYKENVKKEAMKILLLKSIAEQKESSEICFVETNYIDVLKEHTEVEMPGEVVDTHGKVIGEHKGYMHYTIGKRKGFRLFKAHQPHYVLDIIPHKNRIVVGTKEQLEKRQIVLRGLNMFLDQKEFDCYIKIRYRTHKVPCHVKIDGSVASVTLKEPVYGVAKGQAGVFYDEEKVLGGGWIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_RUEPO
Sequence: MRKLFGTDGVRGTANTHPMTAEMALRIGAAVGRYFRREAGGVHRVVIGKDTRLSGYMFENALTAGLASTGMNVLLLGPVPTPAVGLMTRSMRADLGVMISASHNSAEDNGIKFFGPDGFKLSDQAEMEIEEMVATGVRLAQAHNIGRVRRVDDARFRYGERVKSSLTRGLRLDGLKVVVDCANGAAHRTAPEILWELGADVVPIGTSPDGLNINRGCGSTCPRTASEAVVAHGADVGICLDGDADRVIVIDQLGNVADGDQIMALLAARWAAEGRLQGGALVATVMSNLGLERFLGDRGIGLERTAVGDRYVVERMREGGFNLGGEQSGHIVMSDFATTGDGLMAGLHFLGEMMRSGQPSSELVRQFVPVPQLLKNVRFAKGQTPLDAASVQSAIAEAEGVLNGSGRLLIRKSGTEPLIRVMAECEDEALLTRAVDSVVEAVADAVQA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CYOE2_PSEF5
Sequence: MSLKHFIQITKPGIIFGNVLSVAGGFFLASKGHVDLAIFLAAMIGTSLVVASGCVFNNCIDRDIDLKMERTKNRVLVQGLISLEVALVYASILGVAGVALLYYVANPLAALFAVIGFVIYVGFYSLYLKRKSVHGTLVGSLSGAMPPVIGYVAVSNSFDMAALTLLVMFSLWQMPHSYAIAIFRFNDYLAASIPVLPVKRGIRVAKKHILLYILAFLVATLMLTFSGYAGMSYLAVAAAMGMYWLYMAWTGYKAVDDTVWARKLFVFSIFTITALSVMMSVDFKAPTELLLTYAH
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PIMT_RHIME
Sequence: MALRLRSGGIVNHELLKAVEQTPRTLFAPPQYQDEVYSKRLIPLECGSFMEGCDMAVRLLHCLNLKPGQRILEVGTGSGFTAAVMGRIAERVLTIDRYQTLVASAQKNLEKAGLRNVVVRQADGSAGVPGEGTFDRILITAAFNSLPRTFSDHLVSGGTLLVPIMMSETHCRIVRVNRTGSRFDREDLFDAPYLPIVPQVASFL
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_RICPR
Sequence: MKKLTKTNSHRQQKLASIINEVLIEILKRGKMLDKRLFDCPLTITKIIVTADLKIANCYFFPFNTKLTFDEIMDALNNSKHAIRNFITNRINMKFSPEIRFYYDYGFDNAIKIEELLKNSSFKDKTSE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_MYCTO
Sequence: MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_DEIGD
Sequence: MSPEQDTSPELTHFRDGLPRMVDVTEKAATLRTATAEGWVRLPPEARAALEGGTSPKGDPLTVARLGGLAGSKRTADLVLLCHPIPVTGADVRVTLEKAGVRIVATVRTTAPTGVEMEALTAVSVAALNVYDMLKAASKAIEITGVRLLSKTGGKSGDYTAPDT
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: AO1_ARATH
Sequence: MNTSILAILFLIQCVFTLGLHFHPLDPLTPQEINKTSFIVKKSHLGNLKDLTFHYLDLEEPNKSHVLQWLSPNPSKKPPPPRRRSFVVVRAGGQTYELIIDLTTSKIASSRIYTGHGFPSFTFIELFKASKLPLTYPPFKKSILDRSLNISEVSCIPFTVGWYGETTTRRELKASCFYRDGSVNVFTRPIEGITVTIDVDSMQVIKYSDRFRKPIPDKEGNDFRTKHRPFPFFCNVSDTGFKILGNRVKWANWKFHVGFTARAGVTISTASVLDPRTKRFRRVMYRGHVSETFVPYMDPTYEWYYRTFMDIGEFGFGRSAVNLQPLIDCPQNAAFLDGHVAGPDGTAQKMTNVMCVFEKNGYGASFRHTEINVPGQVITSGEAEISLVVRMVATLGNYDYIVDWEFKKNGAIRVGVDLTGVLEVKATSYTSNDQITENVYGTLVAKNTIAVNHDHYLTYYLDLDVDGNGNSLVKAKLKTVRVTEVNKTSSRRKSYWTVVKETAKTEADGRVRLGSDPVELLIVNPNKKTKIGNTVGYRLIPEHLQATSLLTDDDYPELRAGYTKYPVWVTAYDRSERWAGGFYSDRSRGDDGLAVWSSRNREIENKDIVMWYNVGFHHIPYQEDFPVMPTLHGGFTLRPSNFFDNDPLIG
What is the function of this protein?
Oxidizes preferentially the aliphatic diamine putrescine with production of the corresponding aldehyde, ammonia and hydrogen peroxide.  May be involved in the regulation of developmental programmed cell death (PCD) in both vascular tissue and the root cap (PubMed:9681017).  Required for jasmonic acid-(MeJA) mediated early protoxylem differentiation associated with putrescine levels reduction and H(2)O(2) accumulation in roots (PubMed:25883242).
What are the official names of this protein?
Primary amine oxidase 1, AtAO1.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMF_KLEP7
Sequence: MAENTVYFPEAFLAQMRAAMPAHLSFDDFIAACQRPLRRSIRVNTLKISVDDFLSLVAPYGWQLAPVPWCAEGFWIEREDDDALPLGSTAEHLSGLFYIQEASSMLPVAALFADNRQPERVMDVAAAPGSKTTQIAARMGNAGGILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAALPETFDAILLDAPCSGEGVVRKDADALKNWSPESNLDIAATQRELIDSAFHALRPGGTLVYSTCTLNREENQSVIEWLLSRYPQAVEILPLGELFPGAADALTAEGFLHVFPQIYDCEGFFVARLRKTAAIDPLPAPGYKVGKFPFTPLKDREAAAVTAAARAVGLEWDAGHTLWQRDKELWLFPLALEPLFGKVRFSRIGVRLAELHNKGYRWQHEAVIAFAAPQRAFELSQEEAEEWYRGRDVYPQTAPGQDETIVTFQGVPLGLAKRVGSRLKNSYPRELVRDGKLFAGKV
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDH2_LEUMG
Sequence: MLSRVAKLNSRLVSLALLGSQIAFGAITYQHPDDLPSGVDYDFIVAGGGTAGLVVASRLSENSKWNVLVIEAGPSNKDTPETRIPGLADNLPGTRTDWNYTTIPQDALGGRSLNYSRAKVLGGCSTHNGMVYTRGPRDDWNYWAEITDNQALKWDNVLPIMKNTEKFSQDFLDQSMEGHIDPSVHGFDGMLSVVASYTNVSFNNLLLETTRELSDEFPFKLDLNDGKPHGLAWTQYTIDQGAERSSSATSYLESTGDNVHVLVNTHVTRIVSAGNETDFRSVEFAVDANSPKKVLTAKKELILSAGVIASPQILMNSGIGGREELQAIGVDTLIDNPSVGRNLSDQASTLLMFDTTLPNTDYDVAAALTEWDNSRSGPMAYAARLNHLTWVRLPDDKLSGSDPSSGHDSPHIEFQFRQISHQLPPADVPNQVQLPDPDSIGVVLQFSVVNLYSISLGSVTLNNNDPFADPIIDLNMFGDQKDIAILREGVRSARRMFSSQAFKNVVHETVYPPAGVTSDEDLDAFLRTSAVSYLHGVGTLSMSPHSASWGVVNPDFRVKGTTGLRVVDASVIPRAPAGHTQIPVYTFAEHASALIADSYN
What is the function of this protein?
Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin.  The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity.  Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O(2) as acceptor.  May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization (By similarity).
What are the official names of this protein?
Pyranose dehydrogenase 2, PDH 2, Pyranose:quinone oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: UREG_ORYSJ
Sequence: MASHDHDHDHHHHHSHDDGDHHHSHHQDGSHGGGGGSWVGEDGRVWHSHDGLAPHSHEPIYSPGDFSKRAPPLISRRFAERAFTVGIGGPVGTGKTALMLALCRSLREKYSLAAVTNDIFTKEDGEFLIKHGALPEERIRAVETGGCPHAAIREDISINLGPLEELSNLCKADLLLCESGGDNLAANFSRELADYIIYIIDVSGGDKIPRKGGPGITQADLLIINKTDLAPAVGADLAVMERDALRMREGGPFVFAQVKHGVGVEEIVNHILQAWEIATGNKRR
What is the function of this protein?
Required for the maturation and activation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein G, AtUREG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
Protein: AMIE_VARPS
Sequence: MRHGDISSSNDCVGVAVVNYKMPRLHTKAEVLDNARKIGEMLVGMKKGLPGMDLVIFPEYSTHGIMYDTKEMYDTASAIPGEETAIFADACRRANVWGVFSLTGERHEAHPDKAPYNTLILMNNQGEIVQKYRKIMPWVPIEGWYPGDCTYVSDGPKGMKMSLIICDDGNYPEIWRDCAMRGAELIIRCQGYMYPAKEQQILVSKAMAFMNNTYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEEMGINYAELSMGLIRDARRNGQSQNHLFKLMHRGYTGVIHSGDGDKGVAACPFDFYKQWINDPEGAREQVESFTRSTIGTAECPIEGLPNEAARS
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: LIN7C_HUMAN
Sequence: MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
What are the official names of this protein?
Protein lin-7 homolog C, Lin-7C, Mammalian lin-seven protein 3, MALS-3, Vertebrate lin-7 homolog 3, Veli-3.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: Y922_MYCBO
Sequence: MGKGRKPTDSETLAHIRDLVAEEKALRAQLRHGGISESEEQQQLRRIEIELDQCWDLLRQRRALRQTGGDPREAVVRPADQVEGYTG
What are the official names of this protein?
Uncharacterized protein Mb0922c.
Protein: IL20_HUMAN
Sequence: MKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE
What is the function of this protein?
Pro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles in immune responses, regulation of inflammatory responses, hemopoiesis, as well as epidermal cell and keratinocyte differentiation (PubMed:17277128, PubMed:34403503).  Enhances tissue remodeling and wound-healing activities and restores the homeostasis of epithelial layers during infection and inflammatory responses to maintain tissue integrity (PubMed:17277128).  Affects multiple actin-mediated functions in activated neutrophils leading to inhibition of phagocytosis, granule exocytosis, and migration (PubMed:28424238).  Exert its effects via the type I IL-20 receptor complex consisting of IL20RA and IL20RB (PubMed:11706020).  Alternatively, can mediate its activity through a second receptor complex called type II IL-20 receptor complex composed of IL22RA1 and IL20RB (PubMed:11564763).  Acts as an arteriogenic and vascular remodeling factory by activating a range of signaling processes including phosphorylations of JAK2 and STAT5 as well as activation of the serine and threonine kinases AKT and ERK1/2 (By similarity).  Alternatively, can activate STAT3 phosphorylation and transcriptional activity in a JAK2, ERK1/2 and p38 MAPK-dependent manner in keratinocytes (PubMed:23614738).
What are the official names of this protein?
Interleukin-20, IL-20, Cytokine Zcyto10.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_STRA1
Sequence: MGKKIVFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHEQINQSGLDITFHSIATGKLRRYFSWQNMLDVFKVGVGVLQSIAIIAKLRPQALFSKGGFVSVPPVVAARLLKVPVFVHESDLSMGLANKIAYKFATIMYTTFEQSKDLIKTKHIGAVTKVMDCKKSFENTDLTSIKEAFDPNLKTLLFIGGSAGAKVFNDFITQTPELEEKYNVINISGDSSLNRLKKNLYRVDYVTDLYQPLMNLADVVVTRGGSNTIFELVAMKKLHLIIPLGREASRGDQLENAAYFEEKGYALQLPESELNINTLEKQINLLISNSESYEKNMSQSSEIKSQDEFYQLLIDDMAKVTKG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VPS50_MOUSE
Sequence: MQKIKSLMTRQGLKSPPESLNDLGAFESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSADPFDIVKYELEKLPPVLNLQELEEYRDKLKQQQSAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDIRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEETAAAAEGSNVMSTEEATFDRGYVKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIVSRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNHHRIRLDELRMFLENETWELCPVKSNFSILQLHEFKFLEQSRSPSVSPSKQPSATSSKPVTLFEQYCSGGNPFEIQADHKDEETEDVLASNGYESDEQEKSAYQDYDSDSDVPEELKRDYVDEQTGDVPVKSVSRETLKSRKKSDYSLNKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGLSSSRLKTTLNRIQESLIDLEGSADPTATLTAAEERKEKVPSPHLNQLVILTSGDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGKAIDYEQMLLLMMNVKWDVKEIMSQHNIYVDALLKEFEQFNKRLNEVSKRVRIPLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDEIDRPKR
What is the function of this protein?
Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.  Within the EARP complex, required to tether the complex to recycling endosomes.  Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
What are the official names of this protein?
Syndetin, Bcl2-like protein blm, Coiled-coil domain-containing protein 132, EARP/GARPII complex subunit VPS50.
What is the protein family that this protein belongs to?
Belongs to the syndetin family.
What are the subcellular locations of this protein?
Recycling endosome. Membrane. Note=Associates with membranes in an EIPR1-dependent manner.
Protein: ASTER_MOUSE
Sequence: MSTNNMSDPRRPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein.  Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (By similarity).
What are the official names of this protein?
PAT complex subunit Asterix, Protein WDR83OS homolog, Protein associated with the ER translocon of 10kDa, PAT-10, PAT10.
What is the protein family that this protein belongs to?
Belongs to the Asterix family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ALF1_ECOLI
Sequence: MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNNRPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMGAVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKLINAVQDVYLDSKITIA
What is the function of this protein?
Catalyzes the reversible aldol condensation/cleavage reaction between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) to yield fructose-bisphosphate (FBP).
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.