PharMolix/UniProtQA huggingface dataset:
Protein: EIF3B_VANPO
Sequence: MSAALEDIKLEDIPVDDIDFSDLEKQYSVNDTVSFDQYIVVCGAPVIPEGKVAVLKKALTGLFSKAGKVVDIEFPIEDGKTKGFLFVECASPADGNKIIKAFHTKRLDLKHRLFIYTMRDVEKYNDKNFPTEFVEPEIPDFFPTSTLKSWLSDEDGRDQFVLQANEMTTVLWNSAIEDEESVVESRKNWSTNYIRFSPKGTYLFSYHPQGVVMWGGPHFDRLRRFYHPNVRTSSVSPSEKFLVTYSPDPIVVDEEDADCPFTKKNEGHQLCIWDIDSGLLQSTFPVVKSSYLQWPLVRWSYNDQYCARMVGETLVVHDVKKGFAVMDNKTLKVPGIRDFSFAPTGVKIAPFRANDKESVILAYWTPETNNMSCKATIVDVERSRVLKTVNLVQVSNVTLHWQSDSEFLCFNVERHTKSKKTQFSNLEICKLTEKDIPGDKIELKDCVVDFAWEPHGNRFGVIAVRETGDDNIAIPKNVATFFAPEKRDVKDKSTGVKKWLEVASITDKFSNTISWSPAGRYVVVATLVKPNVRRSDFVFYDMDFATDKNMNVTKDVHASLKEVATNSFPSATDMAWDPSGRFLAVWSSSLKHKMENGYKVFNVAGTIVKEEPLNSFKNFAWRPRPASLLTNAEKKKIRKNLKEWTAQFAEQDAMEADAATRDMILRQREMLKDWTEYRAEIGARFEEEFGYKTFNMIPLSNSEDDFTSVEEVKEEVLEESEEKVVE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTAS_THEMA
Sequence: MFLEKLVEMARGKGKKLAVAAANDDHVIEAVYRAWRERVCEPVLFGPEEEITRIIEELVPEWKNPQIIDCPPEEAGRLAVEAVSKGECDFLMKGKIKTGDLMKIYLDERYGLRTGKTMAMVSVMEIPDFPRPLIISDPGMLISPTLEQKVDMIEHCVRVANVMGLETPKVAVVGAIEVVNPKMPITMEAAILSKMNQRGQIKGCIVDGPFALDNVVSEEAAKKKGIQSPVAGKADILILPDIEAANILYKALVFLAKAKSASTILGGKVPVVLTSRADSEETKFYSIALSAVFA
What is the function of this protein?
In addition to acetyl-CoA (100%), the enzyme accepts propionyl-CoA (60%) and butyryl-CoA (30%).
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_MYCS2
Sequence: MTSGPSQPFPSASGPDDGPSWPRILGRLTTGQNLPNGHAAWAMDQIMTGAATPAQISGFAVSMKMKRPTASEVRELADIMLTHARRVPTDEIGTDTVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDDVARSVREVGIGFAFAPQFHPSYKHASIVRREIGVPTVFNLLGPLTNPAGPRAGLIGCAWADLAEVMAGVFAARGSSVLVVHGDDGLDELTTTTTSTIWRVQGGTMERLTFDPAAFGFKRAEISELVGGDASENAAEARAVLGGAKGPVRDAVVLNAAGAMVAHAGLASDAQWLPAWEAGLARAVEAIDSGAAEQLLARWVRFGQQL
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: GLPK_RHILO
Sequence: MSGFVLAIDQGTTSTRAILFDGQMKVAGSGQKEFAQHYPASGWVEHDPEEIWASVVTTVKAALKNAGKAASDVAAIGITNQRETVVVWDRATGKPIHNAIVWQDRRTAPLCQKLKKQGLEKKFTRKTGLLLDPYFSGTKIAWILDKVKGGRKRAEKGELLAGTIDSFLIWRLTGGKVHATDATNASRTLVYNIAENAWDDELLAILNIPAKLLPQVKDCADDYGVTERDLFGAEIRILGVAGDQHAATIGQACFEPGMMKSTYGTGCFALLNTGSDLVRSKNRLLTTIAYRLNGKTTYALEGSIFIAGAAVQWLRDGIKVIGKAEQSGKLADEADPTQNVYLVPAFVGLGAPHWDAEARGAIFGLTRNSGPAEFARAALEAVAYQTRDLLDAMRKDWKGTSAKTVLRVDGGMVASDWTMQRLADILDAPVDRPTILETTALGAAWLAGSKAGVWPKAKEFAKSWALERRFKPEMDIATRSAKLAGWRDAVRRTLSA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TAN_BACIU
Sequence: VQPPHSHGDNFYIWT
What is the function of this protein?
Hydrolyzes ester bonds of tannic acid to produce gallic acid and glucose.  Exhibits no cytotoxicity in vitro in Vero cells or in vivo in a rat model.
What are the official names of this protein?
Tannase, Tannin acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
Protein: OFCC1_CHICK
Sequence: MEKEKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKNCNPGFMSSFKDREASRWQQR
What are the official names of this protein?
Orofacial cleft 1 candidate gene 1 protein homolog, Orofacial clefting chromosomal breakpoint region candidate 1 protein homolog.
Protein: HUTI_STAAR
Sequence: MNDLIINHIAELILPRSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGTHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKHYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTLYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNIQLVMAIAALKLKLSPNEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKV
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BURO1
Sequence: MITLTPGHLTLPQLRRIAREPVQLKLDPASFAKIDAGAKAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARSSVRLLLALKLSSLGRGHSGIRREVMDALITLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGVGEVFIRGERASALDGLRVAGLAPLTLQAKEGLALLNGTQASTALALDNMFAIEDLYRTALVAGALSVDAAAGSVKPFDARIHELRGHQGQIDAAASYRELLEGSPINQSHRDCDKVQDPYSLRCQPQVMGACLDQMRHAADVLLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIADNTKHILAIELLAAAQGVDLRAPYHTSPKLAPVMETIRGKVAHYELDHYFAPDIAVIAKLVGERAFAKVAPFSFASEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: RNBR_GIRCA
Sequence: KETAAAKFRRQHMDSGSSSSSNSNYCNQMMKRRRMTHGRCKPVNTFVHESLADVKAVCSQKNITCKNGQPNCYQSNSTMNITDCRETGSSKYPNCAYKTSQKQKYITVACEGNPYVPVHFDGSVLLPATSTQAQAPLARGQ
What are the official names of this protein?
Brain ribonuclease, BRB.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAJ_OENGL
Sequence: MRDLKTYLSVAPVLSALWFGALAGLLIEINRFFPDALTFPFFS
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RIMO_POLNA
Sequence: MNEIKEKIPRIGMVSLGCPKALTDSELILTRLSAEGYQTSKTFEGADLVIVNTCGFIDDAVRESLDTIGEALAANGKVIVTGCLGAKSGDNGSNLVRQMHPSVLAVTGPHATQEVMDAVHLNLPKPHDPFVDLVPNAFGIAGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVGDVLSEARALFEGGVKELLVISQDTSAYGVDVKYRTGFWDGKPVKTRMLELVQALGEIAAPFGAWVRLHYVYPYPSVDEILPLMATGKVLPYLDVPLQHSHPDVLRRMKRPASGEKNLERISRWREMCPEIVIRSTFIAGFPGETEAEFEHLLDFMREAKIDRAGCFAYSAVQGATANDIPGMLPLGVREERRARFMAVAEAVSSQKLQQRVGATMQVLVDHAPALGRKGGTGRSYADAPEIDGVVKLLPPEKISKTMKVGEFTRARIVGVQGHDLIAVPV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ROSCS
Sequence: MKRLSSAAIREQFLRFFEERGHVRVPSSSLIPGNDPTLLFTNSGMVQFKDTFLGLEQRPYTRATTAQKCLRVSGKHNDLEEVGPSPRHHTFFEMLGNFSFGDYFKAEAIPMAWELLTKVFDLPVERLWFTVFEGDDEVPPDDEAAQLWVAAGADPERVLRFGRKDNFWVMADAGPCGPCSEITIFIGDDLKEMSAKGVNSDDPNYVEIWNNVFMQFERSTMQPLHRPSVDTGMGLERMAMVMQGVHSTYDTDLFIPLIERQLALLGADEPTYRAHVAPFRAVADHSRAVAFLIADGVLPGNTGRSYVLRRILRRAVYQGRTVGFEKPFLADVAAVVIEQMGAVYPELRERADFILETVDLEERQFLRTLSGGVSILKSVIERVRAVGGTVIPGDDAFTLKDTYGFPLDLTQKIAAEHGLTVDEAGYERRMEEQRARGRRAAQFKRAADAEAWADIDLPPTRFTGYLGVSGSGTVQALIVAGDQVAEAVAGQQVQIALDSTPFYAESGGQIGDTGVLIGPRGRARIDDVQRPVPGVIVHYGVVEEGAIAVYETVEAQVDSVRRAAIMRSHTATHLLHRALRDVLGEHAAQAGSLVAPDRLRFDFTHTRPVTPEQLREIERRVNAWIRADTPVAWQELPYQAALEAGAIALFGEKYGDVVRMVTIGCVNGNDALSPAAIAERQRAGFRMCSRELCGGTHVGRSGEIGLFRIVSESSVAAGVRRIEALTGAEAEQWVDAQIATLHNIAARVGAPPSQLGERIEALLAELKQRQRALDELHARQARSNLEGLLANVQAVGDIRFLAAQVEAPDTARLREMGDWLRDKLGSGVVVLAAVIDGKAQILAMATPDLAGRRIHAGNLVKALAPIVGGSGGGRPDMAQAGGREVAHIPDALEHVAAALAAQAGG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P66A_HUMAN
Sequence: MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK
What is the function of this protein?
Transcriptional repressor (PubMed:12183469, PubMed:16415179).  Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666).  Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179).  Efficient repression requires the presence of GATAD2B (PubMed:16415179).
What are the official names of this protein?
Transcriptional repressor p66-alpha, Hp66alpha, GATA zinc finger domain-containing protein 2A.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled nuclear localization requires both CR1 and CR2 regions.
Protein: SYE_LEGPA
Sequence: MTVRTRFAPSPTGFLHVGGVRTALFSWLYAKHHNGQFILRIEDTDRERSTQESVQAILDGMAWLGLNFDEGPYYQTERYARYQQVAQQLLKEGKAYRCQCSKERLEALREAQLAAKEKPRYDGHCRNQILPDSGVPYVIRFRNPDAGIVSFHDEVYGDIHVDNSELDDLILVRSDGHPTYNFAVVIDDWDMKITHVIRGDDHINNTPRQINLFKALDAPVPVFAHLPMILGEDGKRLSKRHGAVSVLQFKELGVLPHALLNYLVRLGWSHGDQEIFSVQEMINSFDLKNVSRGVSSFNYDKLYWLNQHYQKSDSQESVANALQWHFEQAGIDLNQGPDLKDLVAVQAERCKSLAEMCQISQYFYTDTIEYNEDAVKKHLRPVVLEPLMVLHERLKALDEWKNDKIQECINDVSLQFDLNLGKIAQPLRVAVTGSGTSPSIDMTLALLGKNKSIKRLEDALEKIRARASAV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_CLOBL
Sequence: MAKVKITLVKSLIGRKKDQIATVNALGLKKIGNIVEHEETPQISGMIKKVSYLLKVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CEP2_EHV2
Sequence: MASGGVGGTRELFRQFLNKECIWKKSPNSSPYLKIYVATTAISPVFKPDVGGRGRPGSAHAINVTALFMKPKGRRTCAAFYVNGLLLEACVPEVIFTKVVPGVLGLFLIYFGPFAEPRRPFPIPTEPAISAPQNVQLLNRMEMLDTSTHIALSDLGEAVAGREFTSVGKLVWWDGEAFFFYYLSMEYMMCCPTISEHTTLSRFITLLTQCDDRGCVPCHGRKIHANVAGGYTDPGSDGVSTTCLCTLSCAALEKELVPVTKNKSLLSLMFGPMTYQQVTHLRFTPSTRPARIQDIISGVTETGDRVDVRDGTWNLLKMSSLYSRCTLYECQILKRQCLRSY
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid.  Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
What are the official names of this protein?
Cytoplasmic envelopment protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Protein: GLO2_ERYLH
Sequence: MLEIHQFPCLSDNYGFLLHDPDSGETAAIDTPDGKEYLKQAKAKGWTITHIWNTHWHPDHAGGNKDIVEATGAKVIAPQEVEKLSGIDRVVGHGDTVDIGDFTADVIDVSGHTNGHIAYHLPEAGIAFVGDSVFALGCGRMFEGEPKQFWDSLSRIKALPPETMLYCAHEYTAANARFAVHADPENDALVAYVEEITAKRERDEPTVPTQLKRELATNPFLRADDPALVAKWGGDAPHETFAALRAGKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: Y218_STRR6
Sequence: MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKIYQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTAVADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein spr0218.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: PRIB_ECOLU
Sequence: MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: PT1_SALTI
Sequence: MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQEEVILVAADLTPSETAQLNLQKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTAQVKNGDYLILDAVNNQVYVNPTNDVIEQLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKTIC
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_MYCS5
Sequence: MEIFLSIAINILIFWIGYLIGSLNASIIVGKLFYKKDVREFHSKNAGATNSLRVFGYKVAIVILFIDIFKVVFATYFVRIVFPFVFSPKLYFYIPLIAGLAAQIGQAYPIYFKFRGGKGVAATVGLLISINVLLWPIAGVFFFLLLFKTKYVSLSSLLTTLIMIGFISIPWMSQGVLSYATSGFGQFWVNIIIYLFAAALIFWKHRENIKRLLSKTENKMKFKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRF_STRP1
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGAVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: ASPD2_BORPE
Sequence: MTHRIAFIGLGAIASDVAAGLLADAAQPCQLAALTRNAADLPPALAGRVALLDGLPGLLAWRPDLVVEAAGQQAIAEHAEGCLTAGLDMIICSAGALADDALRARLIAAAEAGGARIRVPAGAIAGLDYLQAVAGRDDAEVVYESRKPVAAWRAELPGMGIDPDTLAESRTLFSGPAREAALRFPKNLNVAATLALAGIGMTRTRVEVVVDPQARGNQHRIQVRSPLGEMQIELVNAPSPANPKTSWLVAHSVLATIRRHLARFTIG
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: PLD1_HUMAN
Sequence: MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
What is the function of this protein?
Function as phospholipase selective for phosphatidylcholine (PubMed:8530346, PubMed:9582313).  Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.  May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
What are the official names of this protein?
Phospholipase D1, PLD 1, hPLD1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
Protein: GPN1_SCHPO
Sequence: MTDKEKKPCAIIVVGMAGSGKTTFMQQLNAHLHSKNKPPYILNLDPAVRNLPYEANIDIRDTINYKEVMKQYNLGPNGGIMTSLNLFVTKFDQVLKILEKRAPTVDHILIDTPGQIEIFQWSASGSIICDTLASSWPTCIAYVVDTPRATSTSTWMSSMLYACSMLYKAKLPLIIVYNKCDVQDSEFAKKWMTDFEEFQQAVTKDEGMSSEGATSGYMGSLVNSMSLMLEEFYRHLDFVSCSSVTGEGMDDFLEAVKAKVKEYEEEYVPEMERMKEIQRQTKERQKEAQLSKLMKDMHVSKDKEDVGLTVSDAEDEYNGELVDPDEDDGLTAEDREDMIKQYRVALGISDDISDEKLLEMLTERMKQ
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_XANC5
Sequence: MTASPDPAQRIDALRRRIEDANYRYHVLDEPQMADADYDKLMRELEALERAHPELASADSPTQRVGHLAASRFAEVRHALPMLSLGNAFSEEEVTEFVRRISERLEVKQPLFSAEPKLDGLAISLRYENGEFVQGATRGDGATGEDVSANLRTVKAIPLRLRGEGWPQVLEVRGEVYMPRAAFEAYNAQMRAQGGKVLANPRNGAAGSLRQLDARITAQRPLSFFAYGVGEVSEGALPQTHSAILAQLRAWGFPVSALVEVVQGSDGLLAYYQRIGAARDGLAFDIDGVVYKLDDLAGQREMGFVSRAPRWAIAHKFPAQEQSTTVEAIEIQIGRTGAATPVARLKPVHVAGVIVTNATLHNADQIARLDVRVGDTVIVRRAGDVIPEVAAVVADQRPPGTQAWQMPTQCPVCGSQIVREEGQAVWRCSGELTCPAQRKEAFRHFVSRRAMDVDGLGEKFIEVLVDSGLVKGVADLYLLSVDQLLQLRLISTAESPHAFLREAREHLASGAYAQLETSVVGIGVDLAGERDVPQTWQADLLRAGLPRFDWNRKKIATKWAENLIEAIETSRDTTLERFLFALGIEHVGESTAKALSAWFGDLELIRHLPWPLFKRVPDIGGEVARSLGHFFDQAGNQQAIDDLLQRGVRIGDTHPPSPKLREALSFASVLEDMDIPKVTPVRAQQLAASVDSFAALRTAGADALQQAGVPAPVVAALLQWLDRPENTALANAAQQAMETVLARLPQADALQTGPLDGQTVVITGTLAALTRDAAKQRLEALGAKVAGSVSKKTAFLVAGEEAGSKLDKAQSLGVEIWGEARLLAFLGDHGQQP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DBH_HAEIN
Sequence: MNKTDLIDAIANAAELNKKQAKAALEATLDAITASLKEGEPVQLIGFGTFKVNERAARTGRNPQTGAEIQIAASKVPAFVSGKALKDAIK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.