PharMolix/UniProtQA huggingface dataset:
Protein: GLND_NEIG1
Sequence: MPENLSSALETFKQQRNAAEAHYLKANRVSVFFREYTAAVETLLAALWAEHFQNSALCLMAVGGFGRGEPYPCSDVDLAVVSPAPLSDGIQEQIARFIQTLWDCKLMPSVKSGSVDELCESVRDDITGDTAFLEARFLFGNRQTADELAEKMNVQRNVAAFIEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLAANLPDLLKQRILTRAEAGMLSHGYRRLAHIRIRLHLNAKRAEDRLLFDLQPQVAESMGYQDENRRRQSEELMRVFYRAVKTVKQLGGILTPMLRSRVSSTPVRVTLRIDDDYIQVNNQIAARHTDIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNSENRRRFAGFFRSGNGLTQTLRFLNLYGVLGRYLPAWEKIVGLLQHDLFHIYPVDDHILAVVRNVRRLALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAVQGIADARQFAADHFLTEEESDLLAWLVENHLLMSAVAQKEDIQDPGVLDAFCKRVQTHERLSALYLLTISDIRGTNPKLWNAWRASLLESLFHAAGRCLAGNDGNPHALFGRRRQEAADLLTRAAVPEKQQKKLWNALGSAYFARHQSREILWHAANLVHDFEPPIVRSRILPQSDSFQVMVFMPNGPRLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAELNSFIHGHTVAETQSCNRRISRRSRYMPIAPSITITPEEDYPDRYSVEITAVNRPFLLADMAEVFFAHNVSLRYAKISTLDERVEDSFTVFSPDLKNPKIQSSLKQALLEQLA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: COQ7_COXB2
Sequence: MSNNSRHYSAIDEAILQGQAMLETLFGKPVAQRENPAKGLSQPALTSAEKKQSIGFMRVNHSGEVCAQALYHGQMATAKNPAVRALFTTAAKEETDHLAWCQERLEELGGHTSYLNAFWYTNSFLIGLLAGLSGDPLSLGFVEETEKQVEIHLADHLRKIPSNDLKSRKIVEYMQQDEIQHGLNARSSGAKELPYLVKKLMAFHAKVMTTLAYWI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ORN_PSEU2
Sequence: MQNKQNLIWIDLEMTGLDPDTDVIIEMATIITDSELNTLAEGPVIAVHQSDETLAKMDEWNTRQHGGSGLTQRVRESTVSMAEAEAQTLEFIKLWVPERSSPICGNSICQDRRFLYRHMPTLENWFHYRNLDVSTLKELAARWSPELKFKKGSTHLALDDIRESIAELRFYREHFIKP
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL8J_SCHPO
Sequence: MSSDNTPSINRRNNENPPQSSLPTTSGIVYNMFPACPYPHVQNPAFHGSVDVPQVAQKAFDPQAATVSESANVSRPTPAPVPPAGNTNTPTTSNSNQNLENNVTSAASMPAILNAAGQLEFSPSTNNALCCCTTVHGHPHMPPNLLAASSARLRLPPISTILGGTFADPTFLAAAAAAAVPHYAHATTGSATDASNTSNGNSNPAAVPAGFLSGYSPLSYAYFVAKANELALANQRQSSEAAEQPSSKNNTSGANPPSSNNQEVTSAPIPAAPIVLPFQQPFYPIVCPGCAQGALPQHIPVPHNTEFAQYQPSSRDLQNHPTVDESRLSSVAPPASNTLNHANGNQAENASESSTSQSNDSQGPANTSYPVSVPLPNDAENNHTLSRNPYIPSLNFKDNMSAELSVVATLASNSAQAHPMGQQSDSNYSDHHNNDKRAHVSRRHSTSRKIAQSHTGSSSTSSAANVRYRCTECLQGFSRPSSLKIHTYSHTGERPFVCDYAGCGKAFNVRSNMRRHQRIHGL
What are the official names of this protein?
Zinc finger protein C25B8.19c.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMM_STRPN
Sequence: MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELVLFDEKDQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYHEIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPSKRVDVEILEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LET99_CAEEL
Sequence: MSADYSSEKFKATHLFDEILWHFRSNLSLKTNRRGLATAENSFSGKEAVDFLMIEMPRIIPNNVPERDKMQKFLEFMMDMNVISEAFPKKVKQRRPFSESRIYLFMKTLDELKHPKPRSRRSASFSGARKSAKVAQPASPAATMHRPPKARLPRRLSRSNGNIDKAGIDNSSGGVENHGFDDHKDDEIPKKQRTPKILNRSLESICTEEYTEKREVSEMKEKVYDWLPFFKSRRNHTKVNQPTRRSASLDRNHCVLEQEKAEAALRSQKVTTPPIREAPKDVVFMHPQGPLPAVPSRYQNHRTSIAGSNPALLSRGRMYESIMRRSSVVPVADSVQANNECSFWKTELLGRLEQIYDRTLPCEWASKVDGYDIQWNMIEIDHADGIVKSRCQGLQPDYPQTVIQFMDYLVRYPFVTHKKMDTGLEYNVNRIFITLVNRLEDLNAPLQFDECSLIVNLLCKIDSFAAMLDNGPARRWSKVMISSSASSIEEAGLMVDGFSRDLPACGIRASKYRRRALSPFDNRVNLEIQDEKSYEIREQWLIEAIQLVLLSLPTSRRRKLHKFVTFIQSIETNAVFDLADPSNGSSNNREAAIIGLWTGVCSKCRKQQGMLITAVLLANFQSLFAVPVEFIEQVKRLECEEKDRYSGPRYAKITRSRNDWQPPVPDKPQASPAVFKKPLREVACEKTKKGLFTRLLRK
What is the function of this protein?
Required for the proper orientation of spindles after the establishment of polarity (PubMed:9477332, PubMed:14534135).  May play a role in interactions between the astral microtubules and the cortical cytoskeleton (PubMed:9477332).  Required for asymmetric forces on nuclei and spindles (PubMed:9477332).  Acts downstream of the PAR signaling as an intermediate that transduces polarity information to the machinery that positions the mitotic spindle, possibly by regulating force generation (PubMed:12223405).  Regulates gpr-1/2 asymmetric cortical localization during the first embryonic cell divisions (PubMed:14534135).  Acts antagonistically to the gpr-1/2 signaling pathway (PubMed:14534135).  Regulates mes-1 expression and/or localization pattern during early embryogenesis (PubMed:11003841).
What are the official names of this protein?
Protein let-99, Lethal protein 99.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Enriched at the cell cortex during both meiosis and mitosis (PubMed:12223405). Enriched asymmetrically at the cell cortex in 1-cell embryos (PubMed:14534135). Localizes at the contact site between EMS and P2 in interphase and is excluded from the contact site during prophase (PubMed:14534135).
Protein: INVO_PONPY
Sequence: MSQQHTLPVTLSPALSQELLKTVPPPVNTQQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQQEPQEQELQQQHWEQHEEHQKAENPEQQLKQEKAQRDQQLNEQLEEEKKLLDQRLDQELVKRDEQLGMKKEQLLELPEQQEQHLKHLEQQEGQLELPEQQEGQLKHLEQQEGQLKHLEQQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLKHLDQQEGQLKHLDQQEGQLKHLDQQEGQLKHLDQQEGQLELPEQQEGQLKHLEQQEGQLKHLEHEEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLELPEQQEGQLKHLEQQEGQLKHLEHQKGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLELPEQQEGQLKHLEQQEGQLKHLEHQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLKHLDQQEKQLELPEQQVGQLKHLEQQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLELPEQQEGQLKHLEQQEGQLKHLEHQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQLKHLDQQEKQLELPEQQVGQLKHLEQQEGQLEHLEGQEGQLEHLEHQEGQLGLPEQQVWQLKQLEKQEGQPKNLEEEEGQLKHLVQQEGQLEQQEGQVEHLEEQVGQLKHLEEQEGQLKYLEQQQGQLEVPEQQVGQPKHLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQKDGQLKHLEQQEGQLKNLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEQQQQKQEVQWPPKHK
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: RIMO_SYNE7
Sequence: MTAKPTIAFSHLGCEKNRIDTEHMIGLLAEAGYGIDANEALADVVVVNTCSFIQAAREESVRTLVELAESGKKIVIAGCLAQHFQDQLLAELPEAIALVGTGDYHRIVDVLQRTESGERVNAISQEPSFIADENLPRYRTTTSAVAYLRVAEGCDYRCAFCIIPHLRGKQRSRSIESIVAEAKQLAAEGVQELVLISQITTNYGLDRYGKPMLAELLRQLGQVDVPWIRIHYAYPTGLTPEVIAAIRETHNVLPYLDLPLQHSHPEILKAMNRPWQGNVNDRIIEKLKEALPDAVLRTTFIAGFPGETEEHFRHLQQFIQRHEFDHVGVFAFSPEEGTAAIDLPNPVPDDVKEARRDALMATQQPIAERRNRAQIGRLVDVLIEQEHPSTGLKIGRSARFAPEVDGVVYVQGDAALGQLVTVRITDADIYDLHGEVASAADLFQASRQPSLA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM1_DICDI
Sequence: MTKTETKVEPKAEVKPKEDNVEVIEDDEFEEFEDNMAEGEDNSKEQWEDDWDTDKIDDDFSKQLRAEIESHSTMKS
What is the function of this protein?
Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis.
What are the official names of this protein?
Probable 26S proteasome complex subunit sem1.
What is the protein family that this protein belongs to?
Belongs to the DSS1/SEM1 family.
Protein: XYLA_BRADU
Sequence: MSAKFFEESTPVAFAGQDAGPAPAFRWYDKDRLVHGRRLEDHLRFAVCYWHSLCWPGGDPFGGETFLRPWHHGTDAMAQARAKADVAFELFRLLDVPFFTFHDVDAAPEGASLAESVANLNAIADLFEAKMASAKVRLLWGTANLFTHRRYMAGAATNPDPDIFTYAAGQVRAALEVTHRLGGQNYVLWGGREGYETLLNTDLKRELDQLGRFVSLVVEHKHKIGFNGPILIEPKPKEPTKHQYDFDVATCYGFLARYDLLKDVKLNIEQNHAILAGHSFHHEVALAEALGVFGSLDVNRGDDLLGWDTDQFAMNVPELALVFHEILNRGGFTSGGLNFDAKIRRQSIDPDDLIHAHVGSMDACARAFLAAADMLDAGALTAPLDKRYEGWAGPEGRAILGGQRSLADLADRALGPGFDPQPRSGRQEYLESLVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_NEIMA
Sequence: MARHPYRRLRPAKSGFPEVGISEEGNIRSLHLGSDTVQSSMNLDHPSELVLSYSRAMMGWLLFTDALPQHITQIGLGGGSFARWIDTYLPDTRQTAVDINPQVIAIARNLFELPFEGEKFEIIEADGAEYIKVFRHNTDVILVDGFDGEQIIDALVEEPFFRDCRNALSSDGIFVTNWWSGDKRYQRFIERLLSVFEGRVLELPAESHGNVAVMAFQSSPKEQNIDKLKKRADKLSNAYGLDFHRMLAGLKASNPNNGKHFHL
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_DESAH
Sequence: MELIDLKAEPRKGRGKSAARHLRNNDAVPAVLYGAKMDSMPISVSTLDLTTMVRVHGSSGLFINLAINGDTVPSRTVMLKEIQMDTFDLKYLHVDFQAINVSEKITISVPVEAVGESVGVKAGGMIQLIRRELDIICKPGDMPEVIQIDTTDLEVGDSVHVEEIDLGADVEIPHDVNFTVLTVVPPTSDVEEEEGDEDLEEDVEETAAEEEEGVEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: A3024_ARTBC
Sequence: MVATKSVLSAVALAGVAAAETIDVMVGQGGLKFVPDNIKAKAGDEVVFHFVMGHHDVTLGRYDSPCMPIQGESIWSGVVDTVEKGKGVTFTVPIHDDKTKWIYCSVAKHCQNGMSLVINEPSSGDNQADYKDRAKIVPQSGSPTQVKGGTLGGSGGSGGSSSSSASSSGSSSGTTSAPTPTGGHSSSHPSSTSGSDSSNTQSTPDATLIPSGSIPSATGSGSHSSTPTASPGAAAGLKGSAVLAGVVALGAWIGLL
What are the official names of this protein?
Extracellular serine-rich protein ARB_03024.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted.
Protein: SYS_CAMC1
Sequence: MINLKLLETNYDEFVKKLEGKNVKASLLDELLHTFNELKQKRKALENFQAIQNAKSKELGVKARAGEDVSELKSELNLNKAALADADEIVKQYEEKLEQISFSVPNITDDDVPFGKDENDNVCIKTVLEPTKFDFKPKEHWELGESLGWLDFERGAKLSGSRFTVLRGMGARLGRALVNYMIDFNSARGFELVNVPYLVSSNTLFGTGQLPKFEEDLYKVRDEDLYLIPTSEVPVTNLYNDTIIEAEQLPIKMTCYSACFRQEAGSAGRDTRGMIRQHQFEKVELVSITKPDQSEGVLAEMISCASDLLTSLGLPHRHMLLCSGDLGFSAAKTIDLEVWLPGQGKYREISSISNTRDFQARRAKIRFKDGKKNMLVNTLNGSSLAVGRTLIAIMENYQKADGTIEIPEVLKRYM
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_HYDCU
Sequence: MAASSLPSHNSKFEPKLERAQIAWSEEGVPTSTMFDDVYYSKLDGLAEVNYIFLKHNQLPERFETLLPNSRFCILETGFGAGLNFLTTCLLWLEKSPADAQLHFISLEKFPLTRSELAKAHHAFEEVSEPSNALLDVYPLHLPGWHDVFLYDQRIRLTLWFGHVMKGLPEFDVQVDAWFLDGFTPRKNPDMWQSELYLQMARLSNEATTFATFTAAGDVRRGLAQYGFEVEKAPGYAQKREMCFGRYAHSRPFSSKAPWFERAKGGHPSPKKAIVIGAGLAGATVAYQLASQGLSVTVLEQEKAVAQQASGNLAGAIHPLVTADWNVRSQFYLKGFECSLRWLRPWFDSHSIVGQQNGLMQLAMTETMLQRLQEALTRVGLPKSFAYWCDADQASDLIGQKTDHEGLFFPEAGWVQPTSVVTQCLAHEAIALKQEEAVVSIQPVPDQNSQDWQIMTPNSTYQADVVVVATGALNGDLNEQLNLPIRPVKGQVSHFKAADLKGALKTTVTHRGYSVCGDFGAQSPYAAISGATFEAPDLSPILSDASHIENQRLATEALPNWLADSTDMAGKVGFRPTTPDHLPLIGAVPDFEWMKTAYFEQSHTHAVYRYAEQRYQPGLYVSNGHGARGLMSVFLAAEMIGAMVTGDAQVMPKSLYHAVHPARFAIRHWRSGKR
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNOT9_PONAB
Sequence: MHSLATAAPVPTTLAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in down-regulation of MYB- and JUN-dependent transcription.  Enhances ligand-dependent transcriptional activity of nuclear hormone receptors.  May play a role in cell differentiation.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 9, Cell differentiation protein RQCD1 homolog, Rcd-1.
What is the protein family that this protein belongs to?
Belongs to the CNOT9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body.
Protein: RL1_THEPD
Sequence: MSSQTLVAAGSLEEAIKEALVSSPKKRRFTQSVEMIVTLRDVDVKKPENRLNTVVALPHPAPGKLAKVAVIASGDTALKAKEAGADIVVDKDELQKIGNDKKAAKKLAKRYDFFLAQPDLMPLVGRVLGKYLGPRGKMPQPIPPNVALDALIERFRRSVRIRMKDEPQIACRIGVETQPVEHLAENARAVLAEILKKFPPPNIDRIYFKLTMGRPVKVSREVVRK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FRDD_SALA4
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RISB_NITEU
Sequence: MSYYDNILEIDSNLDGNGLCIGIVMSRFNIDVSEGLLGACTAELTRLGVQEADIVLTTVPGALEIPVALQKLAESDRFDALIALGAVIRGETYHFEVVANESARGLAAVGREYNIPIANGILTTDDEDQATARMAEKGGETARVAIEMANLVLTLDEMDQSAPT
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y3456_BACC3
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAAVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHVS
What are the official names of this protein?
UPF0316 protein BCA_3456.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OVOL2_MOUSE
Sequence: MPKVFLVKRRSPGVSVRSWDELPDDKRADTYIPVSLGCLLRDPPEDCRSDGGSSSGCSSSAGEPGGAESSSSPRAPEPETPELHDAQGTDGHLAAMQRPVARSKIKFTTGTCDNSVIHNCDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSDHPGSTFLKKTSKKLAALMQNKLTSPLQENSTLSEEEEKK
What is the function of this protein?
Zinc-finger transcription repressor factor (PubMed:15225875, PubMed:23319585, PubMed:36228616).  Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (PubMed:24735878, PubMed:24735879).  Positively regulates neuronal differentiation (PubMed:16423343, PubMed:23319585).  Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1 (By similarity).  Important for the correct development of primordial germ cells in embryos (PubMed:28059165).  Plays dual functions in thermogenesis and adipogenesis to maintain energy balance.  Essential for brown/beige adipose tissue-mediated thermogenesis, is necessary for the development of brown adipocytes.  In white adipose tissues, limits adipogenesis by blocking CEBPA binding to its transcriptional targets and inhibiting its transcription factor activity (PubMed:36228616).
What are the official names of this protein?
Transcription factor Ovo-like 2, mOvo2, Zinc finger OVO2, Zinc finger protein 339, Zinc finger protein mOVO.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELD_NITEC
Sequence: MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQTALVQTLDFFTPIVDTPRLFGEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVDVLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQQVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAMQLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLIHDPQTSGGLLLSVVPEASQLVLQALRTYFKPAAIVGTVHPRQDKAVQFE
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: HUNB_DROMU
Sequence: WYSSMFAANIKQEPMSHHHNHHHDNGQHSNSNSDGSPRQSPLPSPNAPATQLEQYLKQQQQHQQHQQHQHQQPMDRCCAAAMTPSPSNNDQNSPGLPNPMQPTMPASMRPSPQPTPTRATAVATALQTGDKLQLTPPMDVTPPKSPAKSQQSSVEPEKEHDLMSNSSEDMKYMA
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFD_AERHH
Sequence: MFNIASAPFAHNRKQTQTLMLLVILACLPGFLAQSWFFGWGTLIQILLALVTALGSEALVLRLRGRPVKPALLDGSAALTAVLIGLSLPPLLPWWMLVLGTAFAIIIAKHLYGGLGQNLFNPAMVAYVLLLVSFPVQMTSWLPPSSIAAYDIGFGDAASVIFTGFSLDGYSMAQLKQGVDGLTMATPLDTLKTGLTQGLTAGEVMTHTVFEGWGGIGWSWVNLGYLLGGLFLLQQKVINWRIPGAILGSLLLAATLGYLMTPDATATPMFHLFSGATMLGAFFIATDPVSASTTPRGRLVYGVLIGVLVYVIRRFGGYPDAFAFAVLLANLCVPLIDSLTRPKVYGARRK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPDL1_CAEEL
Sequence: MPDDEEKLQLLADVERLKKILRQKDEMLEEMEDDLKNQGKPCSSKLSLEERAQELSEQLRDLHVEMDGKNATILDRDALIDSLRSEIDKLEKINKEFANGSVIPEHDDSNSFGESEMLRISEDCQKYKETATALYERNAELEKEAVNLKDEIESMMDHIRDLKNHMETRDEEIARLEGELFDERNSHEGKLAARGNSMFSEVIDAERKVEEDLKVLHGENRALKGMVKRLRMEVEEVEERLRSSTKRFNVTRMTTSDIDVKEMRRLRDRVCHLETERVHLWERMFIKMRSIPKREVGALITGYFKSFELSIASVKGGFDGLMKDNEKYVTIIRGLQQEVENLKADIVQLQFDNKCAHRKAAPVVNKDFEHPLLAAPLKTLNNGRPSFFIKPKNVEPMPQLGHSLSSIAVTPQKPAAKFTTRSSIKDDTSEWAERRMKAQAEKKLATPTPRYNYIKLSEPVPKFKPAVLQMPSTSETKEN
What is the function of this protein?
Transient kinetochore component required for chromosome and spindle pole alignment and chromosome segregation during mitosis (PubMed:18765790, PubMed:18936247).  Functions downstream of the RZZ complex to mediate kinetochore-microtubule attachments and nuclear envelope breakdown during cell division (PubMed:18765790, PubMed:18936247, PubMed:24231804).  Required for kinetochore assembly and localizes the checkpoint proteins mdf-1 and mdf-2, dynein and dynactin to unattached kinetochores (PubMed:18765790, PubMed:18936247, PubMed:24231804).  Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex (PubMed:24231804).  Required for embryonic development (PubMed:18765790, PubMed:18936247).
What are the official names of this protein?
Spindly-like protein spdl-1.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Localizes to microtubules during mitosis (PubMed:18936247). Recruited to the kinetochore by the RZZ complex (PubMed:18765790, PubMed:18936247). Localization to the kinetochore is also dependent on the NDC80 complex and bub-1 (PubMed:18765790). Localizes to the kinetochore during nuclear envelope breakdown and remains there until the metaphase- anaphase transition (PubMed:18765790, PubMed:18936247).