PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_HENDH
Sequence: MSDIFDEAASFRSYQSKLGRDGRASAATATLTTKIRIFVPATNSPELRWELTLFALDVIRSPSAAESMKIGAAFTLISMYSERPGALIRSLLNDPDIEAVIIDVGSMLNGIPVMERRGDKAQEEMEGLMRILKTARESSKGKTPFVDSRAYGLRITDMSTLVSAVITIEAQIWILIAKAVTAPDTAEESETRRWAKYVQQKRVNPFFALTQQWLTEMRNLLSQSLSVRKFMVEILMEVKKGGSAKGRAVEIISDIGNYVEETGMAGFFATIRFGLETRYPALALNEFQSDLNTIKGLMLLYREIGPRAPYMVLLEESIQTKFAPGGYPLLWSFAMGVATTIDRSMGALNINRGYLEPMYFRLGQKSARHHAGGIDQNMANKLGLNSDQVAELAAAVQETSVGRQDNNMQAREAKFAAGGVLVGGGEQDIDEEEEPIEHSGRQSVTFKREMSMSSLADSVPSSSVSTSGGTRLTNSLLNLRSRLAAKAIKESTAQSSSERNPPNNRPQADSGRKDDQEPKPAQNDLDFVRADV
What is the function of this protein?
Encapsidates the genome protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (By similarity).
What are the official names of this protein?
Nucleoprotein, Protein N, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MRAY_SHESR
Sequence: MLVYLAEYLTRFHTGFNVFSYVTFRAILGLLTALMFSLWWGPKLIERLQLMQIGQVVRNDGPESHFSKRGTPTMGGLMILGAIFISVLLWGDLGSRYVWVMLFVLGSFGMIGFIDDYRKVVRKDTKGLIARWKYILQSLAALIIAFFLYTTASNPGETQLVVPFFKDVMPQLGAVFIVLAYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHAQFANYLHIPHLPGSGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGAIAVLVRQEILLVIMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1273_BACC1
Sequence: MAKDSSFDIVSKVELPEVTNAINTALKEIQNRYDFKGSKSDIKLEKEVLVLTSDDEFKLEQVKDVLISKLVKRNVPIKNLDYGKVEAAAGNTVRQRATLQQGIDKDNAKKINNIIKEMKLKVKTQVQDDQVRVTAKSRDDLQAVIAAVRSADLPIDVQFINYR
What are the official names of this protein?
UPF0234 protein BCE_1273.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: YCJF_SALAR
Sequence: MSEPLKPRIDFAEPLKEESTSTFKAQQTFSEVESRTFSPAAIDEYPEDEGTAEAAVDAALQPKRSLWRKMVLGGLALFGASVVGQGIQWTMNAWQTQDWAALGGCAAGALIIGAGVGSVITEWRRLWRLRQRAHERDEARELLHSHSVGKGRAYCEKLAQQAGIDQSHPALQRWYAAIHETQNDREIVGLYAHLVQPVLDAQARREVSRFAAESTLMIAVSPLALVDMAFIAWRNLRLINRIAALYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKTMELCRPLPWFDDDKPRLGDFRRQLIGQLKETLQKNKPTPEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBRC_ECOLI
Sequence: MTQNIRPLPQFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSGPFYCVDEVEHLCPWCIADGSAAEKFAGSFQDDASIEGVEFEYDEEDEFAGIKNTYPDEMLKELVERTPGYHGWQQEFWLAHCGDFCVFIGYVGWNDIKDRLDEFANLEEDCENFGIRNSDLAKCLQKGGHCQGYLFRCLHCGKLRLWGDFS
What are the official names of this protein?
UPF0167 protein CbrC, CreB-regulated gene C protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0167 family.
Protein: RNFG_HAEIE
Sequence: MGTVKITSRYGILLGFIALLCTIISAGIYFLTKDKIDAVIAAQQRELLLQVIPQDYFNNNLLESAVIPQDKNFVGIQKIYFAKKDGNISAYAYETTAPDGYSGDIRLLVGLDPKGEVLGVRVIEHHETPGLGDKIERRISNWILGFTNQSINEHNLSEWAVKKDGGKFDQFSGATITPRAVVNQTKRSALIMLNNQALLQQLSTQVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL21_SOLUE
Sequence: MHAIIETGGKQYRVAPGDVIRVEKLAGDIGSEIELPVKAAFKEGGELVSGKVTGTIVGADRAAKIIVFKFKRKKQYKKTIGHRQSFTDVKIGDVLV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL35_THEMA
Sequence: MPKVKTNRSAAKRFRITKNGKIMRNHAYRSHKTGKKRRNALRALRKKDVVSSADKNRVLRLLGKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GCSPA_STAA9
Sequence: MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNIAEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFYGSIEDLEKIQSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGGPHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDKPIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RNH2_BORPA
Sequence: MEQPDLFGTLAPLPAIIAGVDEAGRGPLAGAVYAAAVILDPDRPVDGLADSKVLKAEQREALAVQIRAQALAWFVASASVQEIDSLNILRATMLAMQRAVAGLAMAPELAMVDGNQAPKLRCAVQTVIKGDALVPAISAASILAKTARDADLLRLHALYPQYGFDQHKGYGTPQHLSLLREHGPCPEHRRSFAPIKAYGAP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPM1_PYRFU
Sequence: MKVSVIIPTYNERENLEELFSRIDNALQGLNYEIVVVDDDSPDRTWEKAQELSSKYPVKVIRRTKEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPKLIEAIKNGSDIAIGSRYVKGGKVENWPFYRKLISKGAIMVGRIALPKIRDIKDPVSGFFALRKEVVEGVELNPIGFKILMEILIKGKYSKVVEVPFTFGIRARGESKLKGKTIFEYLRHIYRLMKWEGEIDRIVKFSIVGLSGILVNEGFLWLFVNLGIPKEIAVIPAVELSILNNFFWNDIWTFKDIRRGSIFSRLLKFHIAALSGAVVNFIVYWILLFLGIHYLIANLVGIVLSFGVRYVINRHVTWAT
What is the function of this protein?
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
What are the official names of this protein?
Dolichol-phosphate mannosyltransferase, Dolichol-phosphate mannose synthase, DPM synthase, Dolichyl-phosphate beta-D-mannosyltransferase, Mannose-P-dolichol synthase, MPD synthase, PfDPMS.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: ATG1_CRYNB
Sequence: MPDSNAQGSREKESGHHRSHKERIGNYVVGAEIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLLENLESEINILKVINHRNIVALTDCFKNDTHIYLVMEYCSGSDLSVYIKQRGNIPTLDFVPKAGSSMALLPTNDEGKIYWPHPPTGGLDERVTRSFLGQLAQAIKFLRAQDLMHRDIKPQNLLLQPATETEVAEGHPYGIPVLKVADFGFARILPAAAMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLFEMSVGRPPFRANNHVELLRRIEKSNDNIVFPDEKERDSKSSDETSIPVPSDIKALIRALLKRKPNDRMGFDDFFNCGVWDGHMAESTEEESLSLDVSTDSSAGLGESDRIRQMVASTEQSKDRLIPTRAPQPLAADAALNPQPAVPISRDTSEGRSRLSTPPSRPTPTRRSTPKYYVGDATPSEPTAIIPPSPSSAPTPTSAPDPGLTTQQSPTSRANPRPIITAASSAQRRMSGKGDGREASSVEEAAPITPPFTGPSPTMARPSRGINEGSPLAAAPPITMGPDGRLERSSALEGSTSGVGTDYVVVEKQTVEINALADELDQASKRPMIRRSSRGSVVSRPVSSFKPISPNITKNDPTLGAISYSPPFALSSTPPFAMQVPRHASGGNSFPRNPSIPSSLNAFPPTTISASPSYGQDAAARFGVSPGSLQTGALARALTNTAIRLIGTSANTAATAIARATAKRRPNIVRVSDMDAAEDDLLCTVEDLARKAFVLFELADERLLAQTQLAQTARTSSTPTGLTGTTPPFSMQAAAAAQAGSRRKSSSSSMNSEVWILRQQEAAANDAVVLYMKSLAFIVKAMDKVKRYWKNRTDVYDGYVASQELNEMGQWLRARFNETFEKAEWAKTQAGDTLLFPDWLVHDKARDTSRQAAVAELQGDLTTAEQGYETSLWLLQALLDESVYENGSIPDEDKVAYERLMVPIKTRLDALRKKLAESSGMTAR
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: THIY_HALH5
Sequence: MKSFKIISLLLAILFLASCQTNTASDDEALETVEVMLDWYPNAVHTFLYVAIENGYFAEEGLDVDIVFPTNPTDPIQLTASGAIPLALSYQPDVILARSKDLPVVSVASVVRSPLNHVMFLAEQDFDSPADLVGLTVGYPGIPVNEPILKTMVEAAGGDYEQVHLMDVGFELGASIVSGRADAVVGTYINHEYPVLKHEGHDISYFNPVDYGVPEYDELVLISNEAYVEESGEVLAAFWRAALKGYEWMVENPDEALNVLLTNQDEANFPLIQEVEEESLSILLEKMENPNGPFGGQDAESWEEVISWLDAHDWLEQPVVAEDAFSSITD
What is the function of this protein?
Participates in a thiamine pyrimidine salvage pathway as part of the ABC transporter complex ThiXYZ involved in the import of thiamine degradation products.  Binds the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP).  Does not bind thiamine.
What are the official names of this protein?
Formylaminopyrimidine-binding protein, FAMP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the NMT1 family.
Protein: MURA_YERPG
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED15_DROME
Sequence: MTEDWQSQKFRQNVISKIHDLLPPNAQDQTKNAGVMENHIFRKSRTKDEYLGLVAKLFMHYKDMSRKSQQQQQQQQQQGGPPPNAEMGGGQNMMQDPLNALQNLASQGNRNPQMMPMGAGGGAPVPGGPGTASNLLQSLNQQRPGQQQMQPMSNIRGQMPMGAGGAGAQQMMQVQQMQQGGNAPGVMNVMGAGGGQNQGQIVGNPGQQMGVGVGMPNQMVGPGPNSGPAVGGAGGPNAAPGAGGPGPNQMQGGPMNVNAMQQMPPMQQIQQNQLGMGMNPMMRMGQGNGMGGPQGMPGQGMQGMPQGPHNVVGGPAGQQQVGGAGLPPNAVQQGGMNPMGGMGVNMPPNLQQKPNMPMGQAGQMFPGNRGGVGVGGQQPGQPFMRSSPSPADAQQLQQQAQLQQMQQQQQQLVVGNQTPTQQPPTPQMPTPNMIPSPALVPQSSPQMMQMQNSQRNIRQQSPSASINTPGQVTGNSPFNPQEEALYREKYKQLTKYIEPLKRMLAKISNDGTNVEKMTKMSKLLEILCNPTQRVPLETLLKCEKALEKMDLISYSGQQFGKSSNPLLEVINTTLQSPVANHTLYRTFRPTLELLFGTDITAPVPAKRPRVEEKSTSFEQEVPHVLQGEIARLDTKFKVKLDTTSQINNKAIRLICCLDDKRLPSVPPVSVSVPEEYPWQAPDCSLAEQEYSATPFLQTVQQALIARISKLPKNYSLSHLLDTWEMAVRQACSPQSKPRAVCELSTLLGV
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Required for activated transcription of the MtnA, MtnB and MtnD genes.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15, dARC105.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_LACLS
Sequence: MAEITSAKATAKTVRVSPRKTRLVIDLIRGKRVADAIAILKFTPTKAAVEVENVLNSAIANAENNFGLEKANLVVSETFINEGPTMKRFRPRAKGSASPINKRTAHITVVVAEKE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AROB_SYNP2
Sequence: MDATTRVELGENSYDIAIAKESLQQIGTFLRPLDLGQKVLIVSNPEIYGHYGETVVNSLQAAGFSVDTHLIPAGEQYKNLASIEKIYDTAFKNRLERSSTLLALGGGVIGDMTGFAAATWLRGINFVQVPTTLLAMVDASVGGKTGVNHPQGKNLIGAFYQPKFVLIDPTVLKTLPVREFRAGMAEVIKYGVIWDADLFTKLEAAEQIDSYATIDPDLLDLILERSCRAKAEVVSQDERESGLRAILNYGHTLGHAVESLTHYETFVHGEGVAIGMALAGAIATRMNLWTTAETQRQDALIKKAGLPTECPNNLAIEAILETLQSDKKVKSGKVRFVLPTKIGEVLITDQVSADLITDVLAPALC
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTDA_METB6
Sequence: MKVALIHSRDDVAGCTIRRHIEQCLDDAHGSANGRTYEFVEVGGRLINAEGVDATLDVNLVIFLSRHSSVNPVPVLTVHATGNFGAAELGGSPRTLAPAAPAMMQATLRALARYCPEGYRVSYEVTHHGPTGLSHPSFFVEIGSTEKEWVDPVAGRAVAEAVLGADPAGAVPLIGIGGTHYAPRETAIALSSRGAFGHIASSRLQVALLDRELVQAMVVQSRAVAAYIDRKAVLPGDVSRISAILDELGIPRLSETEITSLGHLAWEAYREVRALAATVGPQTRCFIHALEGTGPLVLVSLDPVLLSEAKRCDESALVQRFGPLPVAHLATEDNVLLPQFVAFERNSSKIINDLNTLCVKIIRNRESTATENDYLVIRKVRFDPQKARELGVPAGPAYRQLAAGQAVEYDGQIITPDRVSVATETRIHIPGLENYS
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: MNAT_ECOLI
Sequence: MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFEARTLAGYPVLVSEENGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLSRLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQLQLDERTEPDAIG
What is the function of this protein?
Acyltransferase that appears to be required for E. coli optimal growth rate and yield via the formation of N-acetylated amino acids.  Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine (PubMed:27941785).  Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate.  Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine.  Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrates.  Using methionine as a substrate, acyl donor preference is propanoyl-CoA > acetyl-CoA >> butyryl-CoA (Ref. 4).  Likely plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), via its ability to catalyze its acetylation; MSX is a rare amino acid which inhibits glutamine synthetase (GlnA) (By similarity).
What are the official names of this protein?
L-amino acid N-acyltransferase MnaT, L-methionine N-acyltransferase, L-methionine sulfoximine/L-methionine sulfone N-acetyltransferase, L-phenylglycine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. PAT/BAR subfamily.
Protein: ITB2L_MOUSE
Sequence: MLGQCTLLPVLAGLLSLESALSQLCTKDNVSTCQDCIRSGPSCAWCQKLNFTGRGEPDSVRCDTPEQLLLKGCTSEYLVDPKSLAESQEDKERDQRQLSPRNVTVFLRPGQAATFKVDFQRTQDNSVDLYFLMGLSGSAQGHLSNVQTLGSDLLKALNEISRSGRIGFGSIVNMTFQHILKLTADSSQFQRELRKQLVSGKLATPKGQLDAVVQVAICLGEIGWRNGTRFLVLVTDNDFHLAKDKTLGTRQNTSDGRCHLDDGMYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVKTYEKLTTFIPKLTIGELSDDSSNVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYCSNGTSNPGKPSGDCSGVQINDQVTFQVNITASECFREQFFFIQALGFMDSVTVRVLPLCECQCQEQSQHHSLCGGKGAMECGICRCNSGYAGKNCECQTQGPSSQDLEGSCRKDNSSIMCSGLGDCICGQCECHTSDIPNKEIYGQYCECNNVNCERYDGQVCGGPERGHCSCGRCFCRYGFVGSACQCRMSTSGCLNNRMVECSGHGRCYCNRCLCDPGYQPPLCEKRPGYFHRCSEYYSCARCLKDNSAIKCRECWNLLFSNTPFSNKTCMTERDSEGCWTTYTLYQPDQSDINSIYIKESLVCAEISNTTILLGVIVGVLLAVIFLLVYCMVYLKGTQKAAKLPRKGGAQSTLAQQPHFQEPHHVEPVWNQERQGTQ
What is the function of this protein?
During inflammatory stimulation, plays a role in retaining Cxcl13-expressing cells at the site of the inflammatory response.
What are the official names of this protein?
Integrin beta-2-like protein, Protein pactolus.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=In unactivated neutrophils, the majority of the protein is contained in intracellular granules and is released to the cell surface following inflammatory activation or induction of necrotic or apoptotic cell death.
Protein: GCH1_STRSV
Sequence: MDTKKIEAAVAQIIEAVGEDGSREGLQETPQRIAKMYQEIFAGLGETAEEHLAKSFEIIDNNMVVEKDIFFHSMCEHHFLPFYGKVHIAYVPNGRVAGLSKLARTVEVYAKKPQIQERLTVEIAEALMDYLGAQGALVWVEAEHMCMNMRGVRKPGTATVTTAARGVLATDKDLKNEAYKLMGH
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL14_BURP0
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LIPB_RHOP2
Sequence: MINAPLHARQTLDLAGFRPQADARPVEWLISEAPVPYPDAVAAMESRAAAIAAGDAAELVWLLEHPPLYTSGTSGQSTDLLDPRFPLHTTGRGGQLTYHGPGQRVAYVMLDLKRRRPDVRAYVAALEQWIIATLDAFNVRGERRENRVGVWVARPDKGADHEDKIAAIGVRLKRWVSLHGIAINVEPDLSHFTAIVPCGISDPRYGVTSLVDLGLPVTMADADIALRAAFTEIFGATVDAPQVDPAVDAGARSPA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLEO2_ARATH
Sequence: MADTHRVDRTDRHFQFQSPYEGGRGQGQYEGDRGYGGGGYKSMMPESGPSSTQVLSLLIGVPVVGSLLALAGLLLAGSVIGLMVALPLFLLFSPVIVPAALTIGLAMTGFLASGMFGLTGLSSISWVMNYLRGTRRTVPEQLEYAKRRMADAVGYAGQKGKEMGQHVQNKAQDVKQYDISKPHDTTTKGHETQGRTTAA
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth (By similarity).
What are the official names of this protein?
Oleosin 21.2 kDa, Oleosin type 2.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface (By similarity).
Protein: PSMG2_BOVIN
Sequence: MFVPSGDSVPDLAGCTLLMPAVSVGNVGQLAIDLIISTLNMHKIGYFYTDCLVPMVGNNPYATAEENSAELSINAEVYALPSKKLVALQLRSIFIKYKSKSFCEKLLSWVKCSGCAKVVVLSSSHSYHRNDLQLRSTPFRYLLTPSMQKSVQNKIQSLNWEEMEKTPCIPEIDDSEFCVRVPGGGITKLLYDEGCSKEIPIAILLKFVSEGDNIPDALGLVEYLNEWLQIIKPHCEDPTASSLPWKMPSSWRLLFGSGLPPALF
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.  The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity).
What are the official names of this protein?
Proteasome assembly chaperone 2.
What is the protein family that this protein belongs to?
Belongs to the PSMG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOC_MESH7
Sequence: MNFNVIIDHTLLKPQATSQDIKILIEEAKKYNFGAICIAPIWVKLAKKELKNTNIKIVTVIGFPLGSQISAIKQKEASLAIAHGADEIDMVMNIGKFKEKDFQFIINEINQIKKEIGTKILKVIIETALLSPHEIADATKLVSSTNADFIKTSTGFSYRGASEQDLKTIKENKSEKLAIKAAGGITNLADMENFYRLGATRFGTSKSVSIIKNLTDKKNKY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_AQUAE
Sequence: MRMAVSMEDVKKLREMTGAGMLDCKKALEEAGGDIEKAKEILRVKGLAKAEKKAGRETKEGLIYVIVSEDRKKGAMIELNCETDFVARNEEFRKLAERITRHILEKDENKNKSGEGSEILSQELYDEPGKTVETLIKEAIAKIGENIRLSRYCRYDTEDYLHSYVHGGGRIGVLLDFKAPELNDQVLRLVQDVAMQIAAMRPEYVRIEDIPQEVLERERRILREQALQEGKPEHIVDKIVEGKLKKFYQEKVLLEQPFIKEEKKQVKDVIKESGLNVEIKRFCRFELGGL
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.