PharMolix/UniProtQA huggingface dataset:
Protein: NDHK_ACOAM
Sequence: MNSIEFPLLDRTTPNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKLSREISEDRMGSQRENRCFTTNHKFYVRRSTHTGNYDQGLLYQSPPTAEIPSETEPFFKYKSSVSSRELGNESGKEDVSIQNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TILS_HAEI8
Sequence: MDLLSDIEKQLQKATAQGFLIALSGGLDSTVLLSLFAKLCQKQPHLPPLSVRAIHIHHGLSPNADSWAKHCQNLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKHLQIQEMLVTAHHLNDQTETFFLALKRGSGLQGLSAMQQQSVLFGMPIFRPLLGFTRPQLEDYAQQEKLNWVTDESNEDNRYDRNFLRNEILPKLRERWAHFDLAVQRSAQHCFEQQQLINDLLSEIFTEHCQIKNQFKLLQFRQYSLAKQTALLRMWLAKNQLEMPSKRQLTQLINDVIFAKEEANPQFQLVNKVIRRYQDSLYLTKPFSDLTKCTLKLEQNMLNLPDDLGNLTVHENEHNLIFYWQDYSVTLEKTNLPISIRFGYSGKVKHHPKRPREDIKKIWQELSVPPWERNRIPLIFYGNELKSAVGFFRVFDEY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDB2_PYRFU
Sequence: MKGEALKIIEEVLAQGRTAMVEYEAKQVLKAYGLPVPEEKLAKTLDEALKYAEEIGYPVAMKLMSPQILHKSDAKVVMLNIKSPEELKKKWEEIHENARKYRPDAEIFGVLIAPMLKPGREVIIGVTEDPQFGHAIMFGLGGIFVEILKDVTFRIIPITEKDARKMITEIKAYPILAGARGEEPADIEAIVDMLLKVSKLVDDLKDYIKEMDLNPVFVYRKGEGAVVVDARIILKG
What is the function of this protein?
Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate.  Can use other substrates such as phenylacetyl-CoA, indoleacetyl-CoA and isobutyryl-CoA, but not succinyl-CoA.  Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids.  Participates in the conversion of acetyl-CoA to acetate and in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters.
What are the official names of this protein?
Acetate--CoA ligase [ADP-forming] II subunit beta, ADP-forming acetyl coenzyme A synthetase II subunit beta, ACS II subunit beta.
What is the protein family that this protein belongs to?
Belongs to the acetate CoA ligase beta subunit family.
Protein: MED7_PHANO
Sequence: MADADAQRQAEEDANLQLPPYPHPPPFYLKFTTENKDRLDEIKKEDGIDTASDGGKSAQLSTEQILALPTELRYLIPPEPPADTEEFNVFGTINQLKDRDTFNGTMEYISQALAKLLPDWKYEQLYPTTDASNSASSTLDRQRYLFRFLRSILVAYIELLGIVAINPTDELKDDKLKDILTMVTNMHALINEYRPHQARETLISEMERQVEKKKMEIQGVRKMKERVGEVLEGFGREIPSEKAEDRTEEAAVTSEEERKRDAQRQMWQAMDEMLSQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBPD_DROME
Sequence: MPTLGLLFASIGIAVLAMGVPHCRGYTIKEDESFLQQPHYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCNDSFSGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQEALRLDFKLAPVETNFDGNFRKVKVERSEPPQKLKKQFNGFLTPTKYEHHNFTAMESYLRAISSSYPSLTRLYSIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERYGNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTGGVGRANAHGIDLNRNFPDQYGTDRFNKVTEPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQPCELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQVFGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRMDITLMPDDPQHWASANDFRIIENVVNTRYHTNPQVRARLAELENQNGQIASFGYADSEFGTIFNYLKMTSDIGEPEEHKYKLLVVSSLYDTTAPLGREILLNLIRHLVEGFKLQDTSVVELLKRSVIYFLPQTSKFQNVFDMYNSNTSICDPVLGDELAERILGPETDQAKDVFLQFLRSERFDLMLTFGAGNSDLNYPKGDSVLVKFAHRMQRTEFNYSPLQCPPSATRQLHRETTERLTNMMYRIYNLPVYTLGISCCRMPHQKKIASVWRKNIDKIKNFLALVKTGVSGLVQNDKGQPLREAYVRLLEHDRIINVTKNVARFQLMLPHGLYGLEVTAPNYESQMIKVDVEDGRVTELGIIRMHPFTLIRGVVLELPNNDNRATTSIAGVVLDESNHPVRNAKVSVVGQTQLRNFTGSMGQYRISAVPLGTITLKVEAPRHLEATRQMHLIQGGLATENVVFHLKVNEHVFGLPRFLFILCASVLIIVGVIVCVLCAQFWFYRRHRGDKPYYNFSLLPQRGKEQFGLEDDDGGDDGETELFRSPIKRELSQRAHLVNNQTNYSFIIQAA
What is the function of this protein?
Metallocarboxypeptidase that catalyzes the release of C-terminal arginine or lysine residues from peptides and proteins (PubMed:16556608, PubMed:31309630, PubMed:20600119, PubMed:12393882, PubMed:20386952).  Functionally important for processing a broad range of proteins including growth factors, peptide hormones (such as Akh) and neuropeptides (PubMed:16556608, PubMed:27430952, PubMed:31309630, PubMed:20600119, PubMed:20386952).  Consequently, it is involved in a wide range of processes including viability, memory formation, locomotive activity, wing formation, and peptide-regulated behaviors such as starvation-induced hyperactivity, appetitive gustatory preference, and cold and ethanol sensitivity (PubMed:27430952, PubMed:31309630, PubMed:20600119, PubMed:20386952).  Key enzyme in neuropeptide processing (PubMed:31309630).  Involved in regulation of memory formation, possibly via the insulin pathway in neurosecretory cells (PubMed:27430952).
What are the official names of this protein?
Carboxypeptidase D, Metallocarboxypeptidase D, Protein silver.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KDSB_YERE8
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALESGASQVIVATDHPEVVTAVEAAGGEVCLTRADHQSGTERLAEVIERYGFADDQIIVNVQGDEPLVPPEIIRQVAENLAASSAGMATLAVPIESSEEAFNPNAVKVVMDAQGYALYFSRAAIPWERERFAQSKETIGDCFLRHIGIYAYRAGFVRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQEDLDRVRAIMLNK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHEU_ECO7I
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: LEU1_RALPJ
Sequence: MLKNPATKYRPFPAIALADRTWPNKTITRAPIWMSTDLRDGNQALFEPMNAERKMRMFKMLVQIGFKEIEAAFPAASQTDFDFVRELIEGGHIPDGVAIEVLTQAREDLIRRTMESLRGAKRAIIHVYNATAPVFRRTVFNTDREGVKRIAVQSAKLIREIAQTMPETQWTYQYSPEVFSGTELDFALEVCNAVTEVWEPTPEHKIIFNLPATVEMATPNIYADQIEWMHRNLARRDSIILSVHPHNDRGTAVAAAELAVMAGADRVEGCLFGNGERTGNVDIVTLALNLYSQGVDPELDFSHINDVARTCEDCTQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGFAVQKPDAPWEMPYLPIDPADVGRTYDSIIRVNSQSGKGGIAYLLESGYGVAMPRRLQVEFSSTVQKLTDASGREATGADIWALFQQTYLRSDGAIGYVSHRLTERDDGSQHIRLVVNIDDHEHICEGSGNGPLDALVHALSHVLTAPVSIHHYEERALGQGANADAIAFAELAATGVAGSVFGVGVDANLTTASIRAVVGGVNRLIARTGQGMLRRSSAQATVA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: HUNB_PSYCI
Sequence: HMRNHSGTKPFQCTQCSYSCVNKSMLNSHLKSHSNIYSTLCQDCSYATKY
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YACG_ECOUT
Sequence: MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIPSSGDLSESDDWSEEPKQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: EFP_SYNSC
Sequence: MISSNDFRTGTTIEIDGAVWRVVEFLHVKPGKGSAFVRTKLKAVKSGNVVEKTFRAGEMLPQAMLEKSSLQHTYMEGEDYVFMDMATYEETRLSADQIGESRKYLKEGMEVNVVSWNDTPLEVELPNSVVLEIKETDPGVKGDTATGGTKPAILETGAQVMVPLFLSVGEKIKVDTRNDSYLGRENG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H32_TETLE
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y5149_MYCA1
Sequence: MSSLRTHDDTWDIKSSVGTTAVMVAAARAVETEQPDPLIRDPYAKLLVTNSGAGVLWEAMLDPDIAARVEALDEESAAHLHHMRGYQAVRTHFFDTYFADAVAAGIRQIVILASGLDSRAYRLDWPAGTTVYEIDQPQVLAYKSTTLAENGVTPSADRREVAVDLRQDWPAALRAAGFDPTQRTAWLAEGLLMYLPAEAQDRLFTLIGELSPAGSRVAAETAPNHADERRQQMRERFKKVADEIGFEQTVDVGELMYRDDHRADVTEWLNAHGWRATAEHSTAAMRRLGRWIENVPLADDKDAFSDFVVAERR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_5149.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: FLGC_BUCBP
Sequence: MSLFNIFNISGSALETQSKKMDVHAKNLANSDSYIYKNGTLYPYVARIPMLQFDPISENNVGGVKMHTVAGDTSSLKSIYNPNSPIADSNGYSKVSNVDIMSETINAITASKNYQTNLEILNTTKNMIMKTLTIGQ
What are the official names of this protein?
Flagellar basal-body rod protein FlgC.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: SYN_UREPA
Sequence: MQLKIKEIFNQDYVKLEGQKIQIKAWVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARMWAAVVIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSWLAAPLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAFVDLKGMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKNGHQFENNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKMPIESLQWYLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEA_ASPNA
Sequence: MATRPPLSPPVNETEHSVSRITREGKRITYKLNVMQQPERARACGAGAKSSADRRPVDPPPVVELRIFESDPNDDVHKTDITFAYNANFFLFATLETARPMAQGRLAPTPTFPVLTGVPVAGVAYLDRPSQAGYFIFPDLSVRHEGIYRLSFHLYEETKDSKDADESAPIRSPMMKGKPSIPKSFLNFRLEVVSVPFTVFSAKKFPGLTTSTSLSRIIAEQGCRVRIRRDVRMRRRGDKRSDDYDFDEERSHRGRIPDRYSTPDAYANPVERPRSTSIGSVDPAFSYGPEASRRPSATEYGFSNPQAYPRAIPPAPAPAPPSSSTPTPVAPIAPSRSSSYTSHLSFGATRTQYPAPQLPGTPQSATTPTQVYSPHPTYTHARNPSTSTEYEPMPSGYPPSRLPAERSTYSKPLPPIRVLHHSDPTTYRAMANPVPPRAQTPSNAAPSLPPIASISAEYSNNLPQPPSNLAPSPNREPRGFLWDTRAAASSKRPHEDAFSHSERPLYNGMRPDNDSYPSADRRPSDVHRATLLSDRDEMAYKRANGRMATKISPAI
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity).  The velvet complex hat acts as a global regulator for secondary metabolite gene expression (By similarity).  Increases spore dispersing capacity by impacting conidiophore architecture (PubMed:25367340).
What are the official names of this protein?
Developmental and secondary metabolism regulator veA, Velvet complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VeA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enriched in the nucleus in the dark (PubMed:25367340).
Protein: NARPA_DANRE
Sequence: MSQADISTCSAPQRVFQEAVKKGNTKELHSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANREGWSALHIAAFGGHQDIVLYLITKAKYSSGAR
What is the function of this protein?
Regulates independently canonical Wnt and Notch signaling by modulating LEF1 and Notch protein turnover.  Stabilizes LEF1, a pivotal transcription factor in the Wnt signaling cascade, by blocking its ubiquitination.  Involved in angiogenesis; involved in intersegmental vessel patterning during development.
What are the official names of this protein?
Notch-regulated ankyrin repeat-containing protein A.
What is the protein family that this protein belongs to?
Belongs to the NRARP family.
Protein: CLM1_HUMAN
Sequence: MPLLTLYLLLFWLSGYSIVTQITGPTTVNGLERGSLTVQCVYRSGWETYLKWWCRGAIWRDCKILVKTSGSEQEVKRDRVSIKDNQKNRTFTVTMEDLMKTDADTYWCGIEKTGNDLGVTVQVTIDPAPVTQEETSSSPTLTGHHLDNRHKLLKLSVLLPLIFTILLLLLVAASLLAWRMMKYQQKAAGMSPEQVLQPLEGDLCYADLTLQLAGTSPQKATTKLSSAQVDQVEVEYVTMASLPKEDISYASLTLGAEDQEPTYCNMGHLSSHLPGRGPEEPTEYSTISRP
What is the function of this protein?
Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:15549731).  Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells.  Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis (By similarity).  Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands (PubMed:24035150).  May act as a coreceptor for interleukin 4 (IL-4).  Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling (By similarity).  Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:22043923).  Inhibits osteoclast formation.  Induces macrophage cell death upon engagement (By similarity).
What are the official names of this protein?
CMRF35-like molecule 1, CLM-1, CD300 antigen-like family member F, Immune receptor expressed on myeloid cells 1, IREM-1, Immunoglobulin superfamily member 13, IgSF13, NK inhibitory receptor.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CAS2B_SYNY3
Sequence: MDFWLVCYDVRDDKRRRKLAKLLEQRCQRVQYSVFECPLPEKVLTDLLHRRWLKELNLKEDSLRAYPLQRQSRSQAKIFGSPDLYEPPDFLIL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: ATL30_ARATH
Sequence: MPIAKPINQNTTVPYPPQHYSKPPLVIILTVILLVVFFIGFFAIYFCKCFYHTLTEAWNHHYHNGLPENQIQAQQEPVQPPVNPGLEPHIIQSYPLFPFSSVKDLREDKYGLECAICLLEFEEEHILLRLLTTCYHVFHQECIDQWLESNKTCPVCRRNLDPNAPENIKELIIEVIQENAHENRDQEQTSTSNEVMLSRQSSGNNERKIETLPDKFSRSKTTGHSIVRNKPEEEDRYTLRLPDHVKIKVTRRHNNNQTESCISFGELVRNREGRFGEVSGQSLVPESGS
What are the official names of this protein?
RING-H2 finger protein ATL30, RING-type E3 ubiquitin transferase ATL30.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CKE_CONER
Sequence: LLVPLVTFHLILGMGTLDHGGALTERRSADATALKPEPVLLQKSDARSTDDNDKDRLTQMKRILKKRGNKARGEEEHSKYQECLREIRVNNVQQEC
What is the function of this protein?
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.  This toxin has the highest potency for the NR2B/GRIN2B subunit, followed by NR2A/GRIN2A, NR2C/GRIN2C, and NR2D/GRIN2D subunits.
What are the official names of this protein?
Conantokin-E, Con-E.
What is the protein family that this protein belongs to?
Belongs to the conotoxin B superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACHN2_CARAU
Sequence: MTLAVIGLFTLFTSIIAITPAREFVSLAEREDALLRELFQGYQRWVRPVQHANHSVKVRFGLKISQLVDVDEKNQLMTTNVWLWQEWLDYKLRWNPENYGGITSIRVPSESIWLPDIVLYENADGRFEGSLMTKAIVRYNGMITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVKLVLINQQVDRSDFFDNGEWEILSATGVKGSRQDSHLSYPYITYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTIFVINVHHRSSATYHPMSPWVRSLFLQRLPHLLCMRGNTDRYHYPELEPHSPDLKPRNKKGPPGPEGEGQALINLLEQATNSVRYISRHIKKEHFIREVVQDWKFVAQVLDRIFLWTFLTVSVLGTILIFTPALKMFLRTPPPPSP
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit non-alpha-2, GFN-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SYFB_SULIK
Sequence: MVTIVLNKYKLLDKIHIGQQKLEDLLFNLKSEVKPIDENNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYNVTDTEYTLIVDNVRTRPYALAAVVYNAKIDLEELIQFQEKLHGTIGRKRKKVAIGIHDLRKVDSKTIEYKEVPLSYKFVPLYENKELTISEILEKTEQGKLYGNISIANGVSPAIVQDDGEVLSIPPIINSNKTRLDENTKDFFIDVTGTSFEAVAQTLDIIVSNLAEAGGTIGRVKVLKSANFSQLSSPLFLHKIQNVREEYVKKILGIKTSKEEICKHVMRMRMNCDIENGVIRVTVPQYRVDILNEIDVVEDIAMSIGYNNLEPSKYISTNYGSYDYMTLLERKIRELGIGAGYVEISNFVLIKDEKLFSNKYVKILNPVTDEYNAVRNSLIPGLLDFLSKNQHAKFPIRVFETGDVVVYDSSTDTGFRNDKRAAYAIMDNKVSYEDIQAPIHYILKSLGLEVNYKEENNNIFIEGRSASIFYENEKMGVIGEVNPDVLIRFGIEYPAVIAELYISEIAKRLTNQR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDGR2_XENTR
Sequence: MPLNFKPGDLVFAKMKGYPHWPARIDDVKDGAVKPPPNKYPIFFYGTHETAFLAPKDLFPYEKCKDKYGKPNKRKGFNEGLWEIQNNPQASYSLPPASVSSSDSDVPEEKSTARSDGEEEQETGQAILPTAGVSSSDEEGSDKGGVKRKGRTTTPPSAKRTKHSSSEQEPDSASSSEEENSDSDQDFTPEKSTPRIQRRTTNLGKKNKIFAESDSKSDESEDEKKEEEQKKSPSSSSASSPSLSSSDSEAPVKKTPRGRRPAEKPAPKPRGRGRKAEPIPSSDSSDSDSSVDRISEWKKRDEERRRELEERRKKEQEEQLRRLREEEREEEERKKREKAEKGDKSDSDSDSSKSEVIAPPKPKKSSSSSDSEEDKKPVKEVKPVASEIKKGKKEKVRAISDDSDSDKKVKKTIKKTRPSESARKTNQKEKRGERPRGRPSKVEKEKKKPEVITARKVVKKEPTVEEKLQKLHSEIKFALKVDNPDIQKCLDALEELGGLQVTSQILQKNTDVVATLKKIRRYKANQSVMDKAAEVYSRIKARILGPKLESQQKTVQKVNTAEKDPEEEKQTGKVEEDMDASVNGDFLSQRIETAGDKEQDGEGQNLDNKTEMETKQNNHAEHNSNPTEETIECRLISSENQTS
What is the function of this protein?
May act as a regulator of myogenesis (By similarity).  Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs (By similarity).
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 2, HRP-2.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y4XG_SINFN
Sequence: MMLDLTNAKRIGIIGGGIVGWLAAIALRRVFDVDVDVTVIEAPTVFPLGPGEGGSLNLIDTLCRNELDLDVFIGEAGATHKLGVLYENWRGGGIPDRYYRMFGGSGIPEIECRVGGFFPLLSARIAAGENLHTCIPGFELITKKASQVEIDELLATGESGLYPSFHFNHAGFERYLRRVGLARGITSRRAVVHGMRLDDRGHVNAFQLGGEELEVDFAVDASGFARLGLGKVFNTRWCSFANVLPTDRAIIFELEPRGSSPVTRATAMKAGWMWEAPLNRSISAGYAFSSRYADAAMAIAEVENHYGFRVEAKHELSLDQGYFSTAWVNNFVALGTASGFVEPLEAALAAHTFEALRNLERILANGSGIVPARAIEGYNSANARCWTGVRDFLRLHYDSKRIDTPFWRDLAAAELPEGYANLRACFQKRTPRFIDIQPYVGSGWQSLFHEIDWISVAVPLGVVPQAAACAELRRLSTESRSEVQAYVDRLKGTIAKISSTRGYMH
What are the official names of this protein?
Uncharacterized protein y4xG.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HBB_DASNO
Sequence: MVNLTSDEKTAVLALWNKVDVEDCGGEALGRLLVVYPWTQRFFESFGDLSTPAAVFANAKVKAHGKKVLTSFGEGMNHLDNLKGTFAKLSELHCDKLHVDPENFKLLGNMLVVVLARHFGKEFDWHMHACFQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.