PharMolix/UniProtQA huggingface dataset:
Protein: PKDRE_HUMAN
Sequence: MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLRPSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSARGGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEATINASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGSTSSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFLNCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLYLACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIVSDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNMKTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMRVWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSANGPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLTFAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQITPTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIVLQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKPASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFFIDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV
What is the function of this protein?
May have a central role in fertilization.  May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm.
What are the official names of this protein?
Polycystin family receptor for egg jelly, PKD and REJ homolog, Polycystic kidney disease and receptor for egg jelly-related protein.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RBL_JASSS
Sequence: SVGFKAGVKEYKLTYYTPEYKTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEKDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRVPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKVQAETGEIKGHYLNATAGTCEEMIKRAVFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLASEGNVIIREAAKWSLELSAACEVWKEIRFNFEAVDTLH
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VXIS_BPHK0
Sequence: MYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.
What are the official names of this protein?
Excisionase.
Protein: Y1436_METJA
Sequence: MPKMVLLPRMTMALGGYIRETTFPYEEDDEVKPFPYRNVIVGNPTDEPIKIEVPAYNEGWIERHKKLGLIVVPVNEDDDFVGLFQMVKEKVKNAKRE
What are the official names of this protein?
Uncharacterized protein MJ1436.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH1236.
Protein: CDD_BACSU
Sequence: MNRQELITEALKARDMAYAPYSKFQVGAALLTKDGKVYRGCNIENAAYSMCNCAERTALFKAVSEGDTEFQMLAVAADTPGPVSPCGACRQVISELCTKDVIVVLTNLQGQIKEMTVEELLPGAFSSEDLHDERKL
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, CDA, Cytidine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: MSHR_SHEEP
Sequence: MPVLGSQRRLLGSLNCTPPATLPLTLAPNRTGPQCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYYFICCLAMSDLLVSVSNVLETAVMLLLEAGVLATRAAVVQQLDNVIDVLICSSMVSSLCFLGAIAVDRYISIFYALRYHSVVTLPRAWRIIAAIWVASILTSVLSITYYNHTVVLLCLVGFFIAMLALMAVLYVHMLARACQHARGIARLQKRQRPIHQGFGLKGAATLTILLGVFFLCWGPFFLHLSLIVLCPQHPTCGCIFKNFNLFLALIICNAIVDPLIYAFRSQELRKTLQEVLQCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LDL2_ARATH
Sequence: MNSPASDETAPRRNRRKVSRKNYDENAMDELIEKQLGGKAKKKYRTKQDLEKETETEALIALSVGFPIDELLEEEIRAGVVRELGGKEQNDYIVVRNHIVARWRGNVGIWLLKDQIRETVSSDFEHLISAAYDFLLFNGYINFGVSPLFAPYIPEEGTEGSVIVVGAGLAGLAAARQLLSFGFKVLVLEGRSRPGGRVYTQKMGGKDRFAAVELGGSVITGLHANPLGVLARQLSIPLHKVRDNCPLYNSEGVLVDKVADSNVEFGFNKLLDKVTEVREMMEGAAKKISLGEVLETLRVLYGVAKDSEERKLFDWHLANLEYANAGCLSNLSAAYWDQDDPYEMGGDHCFLAGGNWRLINALAEGLPIIYGKSVDTIKYGDGGVEVISGSQIFQADMILCTVPLGVLKKRSIKFEPELPRRKQAAIDRLGFGLLNKVAMLFPSVFWGDELDTFGCLNESSINRGEFFLFYAYHTVSGGPALVALVAGEAAQRFECTEPSVLLHRVLKKLRGIYGPKGVVVPDPIQTVCTRWGSDPLSYGSYSHVRVGSSGVDYDILAESVSNRLFFAGEATTRQHPATMHGAYLSGLREASKILHVANYLRSNLKKPVQRYSGVNINVLEDMFKRPDIAIGKLSFVFNPLTDDPKSFGLVRVCFDNFEEDPTNRLQLYTILSREQANKIKELDENSNESKLSCLMNTLGLKLMGANSVLDTGGALISVIANARRGRSRSHVVAGQCNLPLNPLHFN
What is the function of this protein?
Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA (PubMed:17921315).  Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression (PubMed:17921315).  Required for cytosine methylation of FWA (PubMed:17921315).  Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes (PubMed:25852712).
What are the official names of this protein?
Lysine-specific histone demethylase 1 homolog 2, Flavin-containing amine oxidase domain-containing protein 2, Protein LSD1-LIKE 2.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: CAPG_STAAU
Sequence: MKKLFLKLMKRNLSEDKIRKLGVQVGNDCRFLSVDRSTFGSEPYLIQIGNHVTITSGVKFATHDGGVWIFRKKYPEIDNFHRIFIGNNVFIGINSIILPGVTIGNNVVVGAGSVVTKDVPDNVIIGGNPAKKIKSIEAYETKILENADYTKKLNYNEKKIYLLNKFKENRYN
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Protein CapG.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: HEM3_BORBR
Sequence: MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGKGLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADLPPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGLAARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLGGSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGADAILAELLPTSPAP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ATG26_PENRW
Sequence: MRPLRDDAKRRADRQLSASMKPTSSNRPFSDRVPDRFKDGDDAQFDFTAPPRGMGSRDGNVHYMQQSLFSMIAAVGSKSDFHARFDESSDSDGEMEEQPRVEQTTGKASSRTPPVPSLDPRQPSKRSEPSKLVLEERGRRHQRACSDNKLLQRLPKSDAEGGVNESSNQSDSLLKVPPLRRTRSATPRAAPVLSRMVEAQSHFDLTSATPYLPPNNPDKSMEDQPQSSASALSMRLMKMFEFAKPEKVLVEYACSLLQSMLLQGYMYVTEGHICFYAYLPKKSNVAIKSGYLSKRGRKNPKYHRYWFALKGDVLSYYADPSNLYFPSGHVDLRYGISASLTERKDGDAKDFQVTTDQRTYLFRADSATSAKEWVKALQQVIFRTHNEGDSVKVSFPIANVIDLEESPMADFAETFKIRVIDSGETYAIDEYFFSFFDSGQDAFNYIKGLVNAVSTTTATKEAQDQHDIKHQPESSRTAYKRQSVSSVRVSDQRREDSPRKRSSSVGNENQGSADSFAEQGTGSSPIIQSMTDTTESASQILHRSDVFQAPTMRTLQGRSLDVGESIRRYSDDTTPSASARLDLDAAVGSPCGTLGHNETTEDARYATGQSDLMQSSRPSSVTQLNELVKAGVYPLQRAAGFAEYLKSRSKQMSTLLATESMGYIEKVSGMWIGGQKHYGEREGPLLEDQNVDPEDNEGSFNYGDRFRAHFALPPTEKLQATYYAYLHRVLPLYGKIYISQKKLCFRSLIPGTRTKMILPFKDIENVEKEKGFRFGYHGLVVIIRGHEELFFEFNASDSRDDCAVTLHQNLESVKFLVESGLLAEDERDEVEAAKAEHRMLEEARLDSPEGHDAPPTLTEDSSEIHPFFDDPRASIINFKPPEPLRITCLTIGSRGDVQPYIALCKGLLAEGHKPKIATHAEFEPWIRKHGIDFAPVDGDPAELMRICVENGMFTYSFLREASLKFRGWIDDLLSSAWIGCQGSDLLIESPSAMAGIHIAEALRIPYFRGFTMPWTRTRAYPHAFAVPENRMGGAYNYITYVMFDNIFWKAIAGQVNRWRNNELGLKATTLDKMQQNKVPFLYNYSPSVVAPPLDYPDWIRITGYWFLNEGTDWTPPTELSNFIAQARSDGKKLVYIGFGSIVVSDPSALTRTVIESVLKADVRCILSKGWSDRLGDPASTKTEIPLPPEILQIQSAPHDWLFSQIDAAAHHGGAGTTGASLRAGVPTIVKPFFGDQFFFGSRVEDLGVGICMKKLNVSVFSRALWEATHSERMIVKARNLGIQIRNEDGVATAIQALYRDLEYAKTLARQKSLASSTPFSPTPTAKASPDGGDDDLDDIEEWTFVGDETGFDIAKRMRERAASDADRIGSNMFQ
What is the function of this protein?
Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy) (By similarity).  Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity).
What are the official names of this protein?
Sterol 3-beta-glucosyltransferase, Autophagy-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: GLND_KLEOX
Sequence: MSNSLSNTVPPDLSAQPENPGEWPKSDFNCATIKALIDAFQRWLGEAFDSGIAAERLIEARTEFIDQLLQRLWVEYGFGSINDIALVAVGGYGRGELHPLSDIDLLILSRKKLPDEQAQKVGERLALLWDIKLEVGHSVRTLEECLLEGLSDLSVATNLIESRLLIGDVALFLELQKHIFSDGFWPSEKFFAAKVEEQNDRHQRYHGTSYNLEPDVKSSPGGLRDIHTLQWIARRHFGATSLDEMVGFGFLTEAERNELNECLHQLWRIRFALHLELNRYDNRLLFDRQFSVARRLRYEGESNQPIEHMMKDFFRVTRRVSELNQMLIQLFEEAILALTEDEKPRPIDDDFQLRGTLIDLRDDTLFIREPQAILRMFYTMVRNSSITGIYSTTVRHLRHARRHLTQPLCYIPEARTLFLSMLRHQGGLSRGLLPMHRHSVLWAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVLLKLESFAKEETRSRHPLWLELWPRLTHPELILIAALFHDIAKGAGGDHSILGAQDVLKFAELHGLNCAQTQLVAWLVRHQLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLHYLVCLTVADICATNENLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMENINEQALHQIWNRCRANYFVRHTPNQLAWHARNLLKHDLSKPMILLSSHATRGGTEIFIWSPDRPYLFAAVSAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRTQMIRVGLEQTLSQRSWQPPAPRRQAAKLRHFSVPTEVNFLPTHTDRKSFLELIALDQPGLLARVGQVFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVQQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism (Probable).
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MASZ_BRASO
Sequence: MTRIDAHGLKIAPVLFDFITKEAAPKTGIDPDAFWAGVAAILRDLGSKNRELLKFRDTLQDKIDAWHLANKGKAFDLGAYTAFLKEIGYLLPEPATQKVETANVDDEIGKICGPQLVVPLTNARYALNAANARWGSLYDAFYGTDAIPHDPSEGGKGYNKARGDKVIAKAKAFLDAAAPLATGSHTDVTAYSVIAGQLSAKLKSGNATALKNAGQFAGYQGSAEAPSVILLANNGLHVEVVIDRSHVIGKDDPAGVSDMILEAAVSTILDMEDSVAAVDAEDKVLVYRNTLGLMNGTLSADFEKGGKTLTRALNSDRSYTTPSGGTLALHGRSLLLIRNCGHHMFTDAVLGADGEEIPEGILDAAVTGLLAIHDLKGHSKVKNSRTGSIYIVKPKMHGPDEVALTVELFARVEKMLGLPENTMKVGIMDEERRTTVNLKACIQQASKRIVFINTGFLDRTGDEIHTSMEAGPMIRKNEMKAQPWIKAYEDWNVDMGLIDGLPGHAQIGKGMWAAPDKMADMLAQKIGHPSAGATTAWVPSPTAATLHALHYHQVNVKARQDELTKGGPRAKLGDILTIPVSNSNWAPDDVRQEIDNNCQGILGYVVRWIDQGVGCSKVPDIHDVGLMEDRATLRISSQHLANWLHHGVVSKDQVMDSLKRMAVVVDKQNAGDPLYQPMAPSFDGVAFKAACDLVFEGRTQPNGYTEYILTARRREAKASETAKA
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_STRPM
Sequence: MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PSD_MYCSJ
Sequence: MARRPSTDDLRSGPERFMALVKTTVPPVHPAGLPFIGASLALAAAGRRNRWVRGAGLVAAGANAAFFRHPPRVPPTRPGVVVAPADGLICLVEDAEPPAELNLPARPVPRVSIFLSIFDAHVQRIPISGEVVAVEHRPGLFGSAELAAASEDNERNSVVIRTDTGAQVIAVQIAGLVARRIVCDLTTGDKVTIGDTYGLIRYGSRLDTYLPEGTDIQVLPGQRAVGGETILAELP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAV2_RHIFE
Sequence: MGLETEKADVQLFMDDDSYSRHSGVDYADPEKFADAGGDRDPNQLNSHLKVGFEDVIAEPESTHSLDKVWICSHALFEVSKYVIYKFLTLFLAIPLAFAAGILFATLSCLHIWIVMPFVKTCLMVLPSVQTIWKSVTDVVIAPLCASVGRSFSSVSMQLSRD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin. Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane (By similarity).
Protein: NTPTH_CALMQ
Sequence: MVQGVFVTGPPGVGKTTLIVKVTSRLKERGIRIVGFYTVEEREGGVRVGFRLVNVSNGEWRWLAHVNKVQGPMVGKYHVDVNSIEWGLTLLNQEGDLYVIDEVGPMEMKHPSFLRRVEDVVNSRRFLITIHVKMSNWVNSHLNLGSLIRLSYVNRDAAVDEVLNYLRTILNMA
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: RL20_STACT
Sequence: MPRVKGGTVTRARRKKVIKLAKGYFGAKRTLYKTAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARNHGMSYSKLMNGLKQADIDINRKMLSEIAISDDKAFGELVEKAKAALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISPF_THEMA
Sequence: MESDPMFIGFGYDRHPLVEGRRLVLAGVEIDAPLGSLGHSDGDVLSHAIIDALLGAGCLGDIGTWFPETKEYKDANSLDLLKETVKILEERGFSVVNVDATVVASIVKLSPYREKIVENLKSALETSRVNVKFKSGNTLGFEGEERGISAYAVCLVEEKGCTKST
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL19_BDEBA
Sequence: MAKETNLVRRVSVKAANKNIQSFNSGDTVNVFVKVKEGEKERVQLYKGIVTKIQGSGAAKSFTVRKMSAGVGVERTFPFASPALDKVEIVNVGKVRRSKLYYLRALKGKAAKIESELVSSKAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PHR_CARAU
Sequence: MSGECMLHIRLFSTNLYIRSTLLRSVSDPNTLLHYCSMSANKRKLKRQRESPDSGGGKQPRLAEGRARESGWLLREVNELRRAAQGCEVNKKRLRYLSDTQKIKQGSDGFLYWMSRDQRVQDNWALIYAQQLALAEKLPLHICFCLVPRYLDATYRQYAFMLKGLQEVAKECKSLDIQFHLLSGEPGQNLPSFVEKWKFGAVVTDFNPLRIPLQWIETVKKHLPADVPFIQVDAHNVVPCWEASGKLEYGARTIRGKITKLLPEFLTEIPLVDTHPHSASRAAEPVDWEEVLSSLEVERSVGEVDWAQPGTSGGMNMLESFIDQRLRLFATHRNNPNYDALSHLSPWIHTGQLSAQRVVKQVKREKNASESVASFIEELVVRRELADNFCFYNPSYDNISGAYDWAKKTLQDHAKDSRQYLYTKEQLENAKTHDQLWNAAQRQLVSEGKMHGFLRMYWAKKILEWTASPEEALSIAIYLNDRLSLDGCDPNGYVGCMWSICGIHDQGWAERPIFGKIRFMNYAGCKRKFDVAQFERKYTAVKENSNKDSKKSSSKN
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-2 family.
Protein: QCRA_MYCTU
Sequence: MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPDEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWLLLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSIAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRRKLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGWTPRYQGETIYLARATGTEDGPPFIKMRPEDMDAGGMETVFPWRESDGDGTTVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTTT
What is the function of this protein?
Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex Rieske iron-sulfur subunit, Cytochrome bc1 reductase complex subunit QcrA, Rieske iron-sulfur protein, Ubiquinol--cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EMC10_YEAST
Sequence: MLVRLLRVILLASMVFCADILQLSYSDDAKDAIPLGTFEIDSTSDGNVTVTTVNIQDVEVSGEYCLNAQIEGKLDMPCFSYMKLRTPLKYDLIVDVDEDNEVKQVSLSYDETNDAITATVRYPEAGPTAPVTKLKKKTKTYADKKASKNKDGSTAQFEEDEEVKEVSWFQKNWKMLLLGLLIYNFVAGSAKKQQQGGAGADQKTE
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity).
What are the official names of this protein?
Endoplasmic reticulum membrane protein complex subunit 10.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.