PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_BORPD
Sequence: MIGRITGTLIEKLPPTICVDVNGLGYDIEVPMSTLYALPELGARVTLHTHLTVREDAHILYGFATAAERGAFRELIKVSGIGARTALSVLSGLSVSDLAQAITLQESGRLTRVPGIGKKTAERLLLEMRGKLGADIGATAHAVPDSQTDILNALLALGYSDKESQAALKKLPEGTGVSEGIRLALKALVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL19_LACDA
Sequence: MDPLIQELTKEQLRDDMPEFRAGDTVRVHVRVVEGTHERIQIFEGVVIKKRGTGIGATYTVRKIASGVGVERTFPVNTPRVAKVEVIRHGRVRRAKLYYLRTRSGKAARITERRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL35_MYCBT
Sequence: MPKAKTHSGASKRFRRTGTGKIVRQKANRRHLLEHKPSTRTRRLDGRTVVAANDTKRVTSLLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: KGUA_CHLFF
Sequence: MKDKVSFPFSPDRPLCVPKLFTISAPAGAGKTTLVRMLAEEFPDSFQKTVSLTTRSPRPEEVHGVDYYFVSQEEFLKRLDSGDFLEWVALFGEYYGTSRLEIDKIWKSGKHAIAVIDVEGALALRSKIPTVTIFISAPSLEELERRLKHRGSEQDAQRQERLQHSLIEQAASSKFEYVIINDDLEKSYEILKSIFIAEEHRNVL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_CROS5
Sequence: MVISLSPNGSGRLNHQTTNLSNSLLTTLPYLPNSPLFGTDGIRGKAGELLTAPFALQLGFWAGQVLKSKTTTPGPVMIGQDSRNSSDMLAMAMAAGLTSAGLEVWQLGLCPTPCVAYLTRHSEAIAGIMISASHNPPEDNGIKFFNTDGTKLSSSLGQEIEDGLRGNLLLSVDEIAAWGKILYEPTLVNTYCQFLQDSLPPSLSCQGMKIVLDLAWGASVNVAPAMFKALGAEVICLHETANGDRINVNCGSTHLHVLQAAIQEHQADMGFAFDGDADRVMAVDSTGKVVDGDYILYLWGKSLLERGNLPNNLLIGTVMANLGFERAWQGLGGQLVRTSVGDRYVQSQMWETGAMLGGEQSGHIICHHYGVSGDGVQTALHLAALVHESGVSLAELVKNSFDTYPQILRNVRLEDREKLRYWQECQPLQQAIAQAEVGMGETGRVLVRASGTEPLIRVMVESECPDAANYWVNYLVGIVETHLAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DOPD_XENTR
Sequence: MPFVELDTNLPPQQVPQDLAEKLCSATATILSKPRERVNVTVRTGVSMVVGGSCAPCTQLLVSSIGVVGTAEQNKEHSAKFFQFLTENMGLEQDRILLRFVPLEPWQVGKKATVMTFL
What is the function of this protein?
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
What are the official names of this protein?
D-dopachrome decarboxylase, D-dopachrome tautomerase.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMM1_YEAS6
Sequence: MTDSENESTETDSLMTFDDYISKELPEHLQRLIMENLKGSTTNDLKQTSNNSEFNVSKNGSFKGLDDAIQALQMQSVLHPSSLGSLATSSKFSGWSFAQGFFVGQLSIVLLFIFFLKFFIFSDEPSKSKNPKPAASRHRSKFKEYPFISREFLTSLVRKGAKQHYELNEEAENEHLQELALILEKTYYNVDVHPAESLDWFNVLVAQIIQQFRSEAWHRDNILHSLNDFIGRKSPDLPEYLDTIKITELDTGDDFPIFSNCRIQYSPNSGNKKLEAKIDIDLNDHLTLGVETKLLLNYPKPGIAALPINLVVSIVRFQACLTVSLTNAEEFASTSNGSSSENGMEGNSGYFLMFSFSPEYRMEFEIKSLIGSRSKLENIPKIGSVIEYQIKKWFVERCVEPRFQFVRLPSMWPRSKNTREEKPTEL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1, Mitochondrial outer membrane protein MMM1, Yeast mitochondrial escape protein 6.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: DAPE_RHOP5
Sequence: MPATPDALSIARDLLRCPSVTPADAGALDVLDRLLRGAGFEVHRVTFSEPGAADIDNLYARIGTGAPHLMFAGHTDVVPPGDVSAWSHGAFAGEVADGQLYGRGAVDMKGGIACAVAAVLVYLAACGGQPKGSISFLITGDEEDIAVNGTVKLLQWADARGENFDHCIVGEPSNVEELGDCIKIGRRGSLSGTLIVDGVQGHVAYPQRAVNPVPDIATLIVALSHEPLDHGTAQFQPSNLEFTSVDVGNAATNVIPAQARAKFNIRFNDQHSIKSLQALIEHHLAAACGNRIRARIEWLPSNAGAFVTKPGPFTDLVTAAIEQVTGRRPELNTGGGTSDARFITHYCPVIEFGLVGQTMHKVDERTPVSDLEKLTAIYRGVLERYFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YEJL_ESCF3
Sequence: MPQLSRYSDEQVEQLLGEMLNVLEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINDDPAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: CYOE1_SHELP
Sequence: MAKPMTITKPVATPLPWRAYLEMTKPRVVALMLLTVLVGMCLAVPGAVPVQPLIAGLVGIGMMAGAAAAYNHLIDRRIDGLMARTYNRPLPKGRISITKALTFATAMAILGFALLYWAVNPLTAWLTFASLIGYAVIYTAYLKRATPQNIVVGGLAGAMPPLLGWTAITGEFHGHALLLVIIIFAWTPPHFWALAIHRRAEYAKVDVPMLPVTHGVEFTKTCIMLYTVLLALACLYPVLVGMCGPLYLVGSTLLSCGFIYKAWQLKYRDKPGLAMQVFRFSIYHLMLLFLLLLVDHYLWS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CXB3_BOVIN
Sequence: MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDEFFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCTKLYDDTGKKHGGLWWTYLLSLVFKLLIEFLFLYLLHTLWYGFGMPRLVQCANVAPCPNTVDCYIARPTEKKLFTYFMVGASAVCIVLTFCEICYLIFHRVVRSLHRKRQPGGRGHAPSASRASTCRCHHKLLEAGDLSPDSHDNKLCASAPTMTPI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-3 protein, Connexin-31, Cx31.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RNPA_RHIL3
Sequence: MTISEKKHTVGRLKSRPQFLAVREGEKRRGGFFLLEVLDRKEPDSQARVGFTVTKKHGNAVERNRMRRRLKEAVRLHAGFAMQPGHDYVVVARRDVLDASFQELAAELKSRVETRPKHRRSGDGRPRNV
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PYRB_PECAS
Sequence: MVNPLYQKHIISINDLSREDLELALNVAASLKAKPQPELLKHKVIASCFFEASTRTRLSFETAMHRLGASVVGFADSNNTSLGKKGETLADTISVISQYVDAIVMRHPQEGASRLATEFSGGIPVLNAGDGANQHPTQTLLDLFTIQETQGRLNNINIAMVGDLKYGRTVHSLTQALAKFEGNRFYFIAPDALAMPDYILSMLKEKNIAYSLHNSIDEVVGELDILYMTRVQKERLDPSEYINIKSQFVLRAADLDNARPNLKVLHPLPRVDEITIDVDTTPYAYYFQQAGNGIYARQALLALVLNRELVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CLD10_MOUSE
Sequence: MASTALEIVAFVVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYFANLWKICVTDSTGVANCKEFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDQAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLYMEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRMGYTYNGPTSAMSSRTKYQGGEGDFKTTGPSKQFDKNAYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.  Involved in the regulation of paracellular epithelia permeability to ions in multiple organs.  It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions.  In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function.
What are the official names of this protein?
Claudin-10.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Note=Isoform 1, isoform 2 and isoform 4 localize in the cell membrane and at epithelial tight junctions, whereas isoform 3, isoform 5 and isoform 6 are detected in the endoplasmic reticulum.
Protein: ICP4_HHV11
Sequence: MASENKQRPGSPGPTDGPPPTPSPDRDERGALGWGAETEEGGDDPDHDPDHPHDLDDARRDGRAPAAGTDAGEDAGDAVSPRQLALLASMVEEAVRTIPTPDPAASPPRTPAFRADDDDGDEYDDAADAAGDRAPARGREREAPLRGAYPDPTDRLSPRPPAQPPRRRRHGRWRPSASSTSSDSGSSSSSSASSSSSSSDEDEDDDGNDAADHAREARAVGRGPSSAAPAAPGRTPPPPGPPPLSEAAPKPRAAARTPAASAGRIERRRARAAVAGRDATGRFTAGQPRRVELDADATSGAFYARYRDGYVSGEPWPGAGPPPPGRVLYGGLGDSRPGLWGAPEAEEARRRFEASGAPAAVWAPELGDAAQQYALITRLLYTPDAEAMGWLQNPRVVPGDVALDQACFRISGAARNSSSFITGSVARAVPHLGYAMAAGRFGWGLAHAAAAVAMSRRYDRAQKGFLLTSLRRAYAPLLARENAALTGAAGSPGAGADDEGVAAVAAAAPGERAVPAGYGAAGILAALGRLSAAPASPAGGDDPDAARHADADDDAGRRAQAGRVAVECLAACRGILEALAEGFDGDLAAVPGLAGARPASPPRPEGPAGPASPPPPHADAPRLRAWLRELRFVRDALVLMRLRGDLRVAGGSEAAVAAVRAVSLVAGALGPALPRDPRLPSSAAAAAADLLFDNQSLRPLLAAAASAPDAADALAAAAASAAPREGRKRKSPGPARPPGGGGPRPPKTKKSGADAPGSDARAPLPAPAPPSTPPGPEPAPAQPAAPRAAAAQARPRPVAVSRRPAEGPDPLGGWRRQPPGPSHTAAPAAAALEAYCSPRAVAELTDHPLFPVPWRPALMFDPRALASIAARCAGPAPAAQAACGGGDDDDNPHPHGAAGGRLFGPLRASGPLRRMAAWMRQIPDPEDVRVVVLYSPLPGEDLAGGGASGGPPEWSAERGGLSCLLAALANRLCGPDTAAWAGNWTGAPDVSALGAQGVLLLSTRDLAFAGAVEFLGLLASAGDRRLIVVNTVRACDWPADGPAVSRQHAYLACELLPAVQCAVRWPAARDLRRTVLASGRVFGPGVFARVEAAHARLYPDAPPLRLCRGGNVRYRVRTRFGPDTPVPMSPREYRRAVLPALDGRAAASGTTDAMAPGAPDFCEEEAHSHAACARWGLGAPLRPVYVALGREAVRAGPARWRGPRRDFCARALLEPDDDAPPLVLRGDDDGPGALPPAPPGIRWASATGRSGTVLAAAGAVEVLGAEAGLATPPRREVVDWEGAWDEDDGGAFEGDGVL
What is the function of this protein?
Plays an essential role in the regulation of viral gene expression by both activating and repressing host RNA polymerase II-mediated transcription.  Binds with high affinity to the sequence 5'-ATCGTC-3'.  Activates transcription by recruiting a form of the host TFIID to promoters and stabilizing the pre-initiation complex formation.  Negatively regulates its own transcription.  This immediate early (IE) protein is absolutely necessary for the transition from IE transcription to later viral gene transcription.
What are the official names of this protein?
Major viral transcription factor ICP4, Alpha-4 protein, Infected cell protein 4, Transcriptional activator IE175.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP4 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Virion tegument. Note=Localizes to the cytoplasm when phosphorylated.
Protein: ZN681_HUMAN
Sequence: MEPLKFRDVAIEFSLEEWQCLDTIQQNLYRNVMLENYRNLVFLGIVVSKPDLITCLEQEKEPWTRKRHRMVAEPPVICSHFAQDFSPEQNIKDSFQKVTPRRYGKCEHENLQLSKSVDECKVQKGGYNGLNQCLPTTQSKIFQCDKYMKIFHKFSNLNGHKVRHTRKKPFKYKEFGKSFCIFSNLTQHKIICTRVNFYKCEDCGKAFNGSSIFTKHKRIHIGEKSYICEECGKACNQFTNLTTHKIIYTRDKLYKREECSKAFNLSSHITTHTIIHTGENPYKREECDKAFNQSLTLTTHKIIHTREKLNEYKECGKAFNQSSHLTRHKIIHTGEKPYKCEECGKAFNQSSHLTRHKIIHTGEKPYRCEECGKAFRQSSHLTTHKIIHTGEKPYKCEECGKAFNKSSHLTRHKSIHTGEKPYQCEKCGKASNQSSNLTEHKNIHTEEKPYKCEECGKAFNQFSNLTTHKRIHTGEKPYKCEECGKAFNQSSILTTHKRIHTGEKSYKCEECGKAFYRSSKLTEHKKIHTGEKPYTCEECGKAFNHSSHLATHKVIHTGEKPYQCEECGKAFNQSSHLTRHKRIHTGEKPYQCEKCGKAFNQSSNLTGHKKIHTGEKLYKPKRCNSDFENTSKFSKHKRNYAGEKS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 681.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RGS_DROME
Sequence: MHHHHPPLPITGASGSTAVGTGAAAAEDASPAANSGPAPISTSTTPSGSNSQQHQRRRKKRANYNYNGIRTVEVRRGYNGFGFTISGQQPCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLIGNSFGSIRMQIAENYYSDSSDEENAHATLRGQLLAASLRHKPRFLHHKAKLHRLRNSPQKKLNPPEAVEPHKSKSSPDHPTLKPVLEDPPLTANLSKAADVANVSAMVRAVGSAALECRVIVGYLGTIEMPKQISHSSKLQTVRSCIRKLRQEKRQPTIVLMCITPDSLSLQSSSGGVLATYSSARLNFVSSSSESENRFFGLVTSAVHNTQIEEEYEPSAGSAAAAGHISISHSCHVFVIDTKLIEHAQHLQRAHEFRLQCTRDPISNLCLEFPNNSEYVVNLVRSMYTMRILPPASRSHQADYEAGAGAAAAGGAVAAAHSPQPSNHSEISTTTSNSDSGIGFNNDCTNISDRILVVDFLAAGAGAAAAAHAGPPTYPAPARPLGIVGIPDNRLTVRAMPDHSALLRSPPASSSLRRPNLLASFNLIQSPATNLTSTRSCDDVLNLFVDDSPRTLAAVASMDDISLHSAAPSLDEGHTFAHPACVPRKMRRSLALETPTTPHKLSAQVFGQPGSRHSLGFEAIDSVQSSVSGACMDQTMDTWASLQNLHKSHKDRTSMSASSSSHCLLEATNSEPDLGNRALPANASPFRRAWGQSSFRTPRSDKVAKEQQQLGQSSPVRRTASMNASDNDMYIKTLMLDSDLKSSRSQHQLSLLQVPKVLTTPAPPSAITASVAAEGAAQDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFWTACERYRLLESEADRVAQAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSLMKFDSYQRFIRSDLYKSCVEAEQKNQPLPYSGLDLDELLKTNFHLGAFSKLKKSASNAEDRRRKSLLPWHRKTRSKSRDRTEIMADMQHALMPAPPVPQNAPLTSASLKLVCGQNSLSDLHSSRSSLSSFDAGTATGGQGASTESVYSLCRVILTDGATTIVQTRPGETVGELVERLLEKRNLVYPYYDIVFQGSTKSIDVQQPSQILAGKEVVIERRVAFKLDLPDPKVISVKSKPKKQLHEVIRPILSKYNYKMEQVQVIMRDTQVPIDLNQPVTMADGQRLRIVMVNSDFQVGGGSSMPPKQSKPMKPLPQGHLDELTNKVFNELLASKADAAASEKSRPVDLCSMKSNEAPSETSSLFERMRRQQRDGGNIPASKLPKLKKKSTSSSQQSEEAATTQAVADPKKPIIAKLKAGVKLQVTERVAEHQDELLEGLKRAQLARLEDQRGTEINFDLPDFLKNKENLSAAVSKLRKVRASLSPVSKVPATPTEIPQPAPRLSITRSQQPVSPMKVDQEPETDLPAATQDQTEFAKAPPPLPPKPKVLPIKPSNWGVAQPTGNYCNKYSPSKQVPTSPKEASKPGTFASKIPLDLGRKSLEEAGSRCAYLDEPSSSFV
What is the function of this protein?
Acts as a regulator of G protein signaling (RGS).  Modulates G protein alpha subunits nucleotide exchange and hydrolysis activities by functioning either as a GTPase-activating protein (GAP), thereby driving G protein alpha subunits into their inactive GDP-bound form, or as a GDP-dissociation inhibitor (GDI).  Confers GDI and GAP activities on G(i) alpha subunit Galphai.  Confers GAP activity on G(o)-alpha subunit Galphao and G(i) alpha subunit Galphai.  Involved in the dorsal-ventral axis formation of the egg.  Acts as a G-protein signaling for glial cell differentiation during embryogenesis; Galphai, Galphao and the G-protein coupled receptor, moody, are required in the surface glia to achieve effective insulation of the nerve cord.  May be essential for nurse cell dumping during oogenesis.  Required in neuroblast asymmetrical cell division.  Plays a role in stress resistance and life span control.
What are the official names of this protein?
Regulator of G-protein signaling loco, RGS, Locomotion defects protein, Loco.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Apical cell membrane. Note=Recruited from the cytosol to the plasma membrane by the G(i) alpha subunit. Colocalizes with moody at the plasma membrane. Localizes as a crescent to the apical cortex in interphase and forms an apical crescent and segregates into the apical daughter cell at telophase. Colocalizes with Galphai and raps/pins at the apical cortex throughout mitosis.
Protein: ENO_TRIV2
Sequence: MSNIVDTAIEAIVAREILDSRGRPTIEAEVHLLSGAVGLAQVPSGASTGTFEAHELRDKDKSRYGGKGVLKAVHNVNEVLAPKLIDLDAINQELIDRTMIALDGSGNKSNLGANAILAVSLAAARAGAASLGIPLYRYLGGPLANLLPVPLMNVINGGAHAANNVDFQEFMIVPVGATSFREALRWGAEVFATLSEVLHDKGLLTGVGDEGGFAPNLESNQVALELLVAAIEKAGYKPGEQVALALDVAASEFYKEGQYVYDGRPHAPTEFIDYLGQLVDQYPIVSIEDGLHEEDWQNWQLLTQKVGSRVQLVGDDLFVTNATRLQKGIQEKAGNAILIKLNQIGSLTETLETIDLGTRNGFRSVISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGAVGLGPK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AI8_USTMA
Sequence: MVRWLYSTNAKDIGTLYLIFAVFAAMIGTAFSVLIRMELAAPGVQYLNGDHQLYNVIITAHAFVMIFFMVMPAMVGGFGNYLVPVMIGAPDMAFPRLNNISFWLLPPSLILLLASAFVEQGAGTGWTVYPPLSGLQSHSGGSVDLAIFSLHLSGISSMLGAMNFITTVLNMRNPGMTLHKLPLFVWAIFVTAILLLLSLPVLAGAITMLLTDRNFNTSFYDPAGGGDPILYQHLFWFFGHPEVYILIIPGFGMVSHIVSAFSGKPVFGYLGMVYAMFSIGILGFLVWSHHMYAVGLDVDTRAYFTAATMIIAVPTGIKIFSWLATLYGGSLRITTPMLFALGFIALFTIGGLTGVILANASLDVALHDLKYKTTTYRNSYYTTGPLYYKPSTLSRQQLDAFVVGLIDGDGSLQVNHWRYKILQFRLVVKLADKPINYEMLCIIASIYGGNVRRVQKEGGYVIWTVNDKKTFTRTILPLFSKCAPLTSRMHLQLQFFLVFFNDPNVDLYFKLRDSKYIDREKVSPLFNKAPSYFSDWLGGFIESEGSFVNRSSGGSSFSIAQNHDYYLIEAIRDFYGVSHLTISNKFGKVSGYPLYEVSIASLAGVTHVIYHCVPLLQGYKYHQLVEFINKSKSLKAVTKEFLNLL
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease aI8.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: URE3_CITK8
Sequence: MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEDGRHVLTRDRVMEGVPEMIPDIQVEATFPDGSKLVTVHNPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4OA_SINFN
Sequence: MNVLKRGSDQDNWWQAYPGLYARELAAYEGHGASHRPLIQQDGTLILEVLWPMDSAGSIRLNVGYSPLHPFCRPSISAPELQLERHQNPFTRDLCLLTQDSAQWYPHQMVADFIAERLSQVLQVMTLRRNEQWSEAASLEEQAPDPVTPYHMHVAEEYSAVFFDGQQTVPNAPLGTAVFLLQDRLERGRSPPFQAILSKVEPLSGTWMAKPFDLPKRAGPWKNVIGRWIRLEPPFPEAPEEILAAAEKAIERQSALFPAHLKKLGSIADDDLSITAVVFQEELSYGPDNKGNGWFFLVSRRVPGSRRRQVSLVRGYRLSSDMLSRLPVASALKSKKVVLVGCGAIGSFAAVELARSGVGQLTIIDFDLVEPGNTVRWALGRSVWGLPKTTALHDFLYHNYPWTNVGRGHAKVGSAISNVDDVRKLEGNPMRWLRALIEDADIVVDTSASTECQGALAYMCRSIGKRYVLGHATEGAAGGVVARFKPGAPGCYVCLQQHWSGKTLPLPTIDSSGTIVPTGCNAPTFTGGAFDLQEVSMEVVRSTIGLLAPDVYDSGDWQLSILDLTENGRRILPRWKAETIAPHSSCSCGASQG
What are the official names of this protein?
Uncharacterized protein y4oA.
Protein: PALA_CRYNJ
Sequence: MSNFLPIPTKAATPLPSFAKHLLDYISAHFRDTHSEAFRKDVDVLVGMRKDWVEAKLEAHPEIIRAFMRYHAQLAFLSTKFPSDINLPFAYYLPFPATFSLSPDAPISLSSLTFERACVLFNMTALYASMAAAERRAEAEGIKRALGYLTAAAGVLEYLITSVLPTLRSELSSPQAAGYDMTESFLGTLKEFVLAEAQECYWQQAVLQGTYKNGLIGKLSMKVSEYYKAALASMNGTDYPSSSYFPLNWTAHMNVKQMHFEAAAQFRLSQEDLEKSRYGEEIGRLKVAESLAKKGLDAARKGVADSVVSDLKQLHAAIKSSLERAVRDNDLVYVQPIPPANQLAPIVGVGMVKVNVPAEVAEPVAWLMGGKAGMEPLFSGLVPYGVHLALSIYDDRKDTLVRDLDGKREELDGLAASTLQSLNLPGSIQALDRPVGLPPSLLKKSEEVASSGGIERIRSLLDEVNRLAHANVQSLNEAMDILDQEATENESLIARQPELQQTRQPSHVANQPLIQMAEQYEATIKQAGGSDATVRAKWEEWARLVGILAAGEMEMEDYVPGTTSPSGSLPPSVRPLRASLEELDDRIAHRARLVREARQISAADDIRPEVLKEAAKLAHGGSGDVKTEWFEDLFEKGLEKYMGVKREMDEEVAKHDELLEQIRTQNESFLSERKDDPIIKERERRLQDMDLAYWKWREIVDNAEEGIKFYNSFAEMLHGFKAACGQFLNTRRIDVGQMTTQFQQQMNVSEPQQQPEPRYQSPSPQSFQPSFSPSPSHFQPSAPSSFSSSPVRSPAPSAPARRESPPKTLSFLPHPSSSAWQPASVDFLPPPPPPPILRSGGIQSQPKVAPPVTPSITAIRDQTQGTPRRMTRAAAAAAERDEATERNKYSSGGPRRKGGGVV
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.  May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).
What are the official names of this protein?
pH-response regulator protein palA/RIM20.
What is the protein family that this protein belongs to?
Belongs to the palA/RIM20 family.
Protein: FLHD_RALPJ
Sequence: MDTQDIVSEISELNLTYLMLAQQMLAKDRDAALFRLGISEELADILLTMSPAQIVKLASTNMMLCRFRFDDHAILGLVTQPHRDKGLQQSQMSILLARQAVEQIS
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O165_CONST
Sequence: MKLTCVMIVAVLLLTACQLITADDSRGTQKHRSLRSTTKVSKSTSCMEAGSYCGSTTRICCGYCAYFGKKCIDYPSN
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like SO-5, Omega-conotoxin SO5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.