PharMolix/UniProtQA huggingface dataset:
Protein: ENV_SIVMK
Sequence: MGCLGNQLLIAILLLSVYGIYCTQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNGDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDRWGLTKSSTTITTAAPTSAPVSEKIDMVNETSSCIAQNNCTGLEQEQMISCKFTMTGLKRDKTKEYNETWYSTDLVCEQGNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPLTDRPKQAWCWFGGKWKDAIKEVKQTIVKHPRYTGTNNTDKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRDVTTQRPKERHRRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWTDGNQTSITMSAEVAELYRLELGDYKLVEITPIGLAPTDVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASFRLTAQSRTLLAGIVQQQQQLLGVVKRQQELLRLTVWGTKNLQTRVTAIEKYLEDQAQLNAWGCAFRQVCHTTVPWPNASLTPDWNNDTWQEWERKVDFLEENITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLASWIKYIQYGIYVVVGVILLRIVIYIVQMLAKLRQGYRPVFSSPPSYFQXTHTQQDPALPTREGKEGDGGEGGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRAYQILQPILQRLSATLRRIREVLRTELTYLQYGWSYFHEAVQAGWRSATETLAGAWGDLWETLRRGGRWILAIPRRIRQGLELTLL
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: FDB2_FUSPC
Sequence: MSCLPEPTVLTQLWVDNPPRYSQAQLQDYLKVIKLPQRFLNSAVLKDSSLAHTKEHGLPLLKAITRYHACNVPFENLELHYSAHKTITLDPVELFEKIVTRRRGGRCMENNTFLGTVFRSFGYEVRDCGGRVARAMSPYPDVRKNQAYTYDGWNHMLNLVYLEDEWYVVDVGMGSMGPNLPFPLRHGFETMSIAPRKIRLQRRPIAESHASNPTKGTELWCYDVCLKPTKDGTEVWIPTYAFTETEFLPQDYEVMSWFTSTNPRSFFTRYVTCTKMIQDEEKEEIIGNLTLFKDTIRETIGNQRKVVRECKTEEERIQALVEIFDVNLTDEEKNGLPEERRLA
What is the function of this protein?
N-malonyltransferase; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:26296598, PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the gamma-lactamase FDB1 to aminophenols (PubMed:26296598).  FDB1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26296598, PubMed:25727347).  The N-malonyltransferase FDB2 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:26296598).  FDB2 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:26296598).  The cluster contains also 2 transcription factors (FDB3 and FPSE_08121), an aldo-keto reductase (FPSE_08125) that possibly associates with a ketone component of BOA and MBOA degradation, an esterase (FPSE_08126), an acyl-CoA transferase (FPSE_08120), a solute carrier protein (FPSE_08119) and a transmembrane transporter (FPSE_08127) proposed to shuttle metabolites of benzoxazolinone degradation (Probable).
What are the official names of this protein?
N-malonyltransferase FDB2, Fusarium detoxification of benzoxazolinone cluster protein 2, FDB cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: PTR1_LEIMA
Sequence: MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
What is the function of this protein?
Exhibits a NADPH-dependent biopterin reductase activity.  Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin.  Confers resistance to methotrexate (MTX).
What are the official names of this protein?
Pteridine reductase 1, H region methotrexate resistance protein.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PYRG_FRATN
Sequence: MNSNTKIIFVTGGVVSSLGKGVTAASLATLLESRGLNVTMMKLDPYINVDPGTMSPLQHGEVFVTEDGAETDLDLGHYERFIRNKMTQANNFTTGKVYQSVLRRERKGDYLGATIQVIPHITDEIKRRICSGIADDVDVAIVEIGGTVGDIESQPFLEAIRQLRIELGRNRTLFVHLTLLPYIKVAGEIKTKPTQHSVKELRGIGIQADVLVCRCEKKFDDSEKRKIALFTNVDQDCIFTAEDVDTIYEVPLKYNQQGFDAKLVELLNLNAKEADLSEWQNVVNTIRDVKGEVTIAMVGKYVSLTEAYKSLNEALYNAGYKKGVKVKIKFVDSEDVNENNVESYFKDVAAILVPGGFGSRGVEGKIISIKYARENQIPFLGICLGMQLAVIEYARNILGIKDAHSSELEPTTANPVIGLITEWQAEDGTVHQRTHSSDLGGTMRLGGYKCVLKQGSRAREIYQADEVVERHRHRYEVNSNYVERLEEAGLIFSGRSEDNKLMELIEIPQHKWFIACQAHPEFTSTPRYGHKLFESYIQAAIENSNN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PLP_RICTY
Sequence: MKKLSVIFLSVSMLSSIAFCDQDKVVATYKGGEVKESQIMQEFKPQLNLQSGETIKNFDDFPLQDQEKLIKIYVNNLLLKEEVAKSSITSSKEFQEKLENAKNQLAQQELLANYIKSNITDKMFDDEYNKYVDNLKGKEQIKVAHILVKSQKEANTVKTKLSKGGNFNKLAEEFSLDKATASNGGVIGYIILNQSGQLVPEFENKAFALKVNEVSTPVKTDFGWHIIKVLEKKPVPIPTKKEAKVTIDNILAAEILKKYISDLEAKADLKIMLPKANSKTGS
What are the official names of this protein?
Parvulin-like PPIase, Peptidyl-prolyl cis-trans isomerase plp, Rotamase plp.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: UB2V2_DANRE
Sequence: MAASSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPARTNYENRIYSLKVECGPKYPEVPPTVRFVTKISMNGINNSNGMVDARSIPILAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYSN
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The ube2v2/ube2n heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RS11_DEHMB
Sequence: MAVKKRAGAKKKEKKVIPVGKAYVQATFNNTIVTLTDLQGNVIAWASCGTAGFKGSRKGTPYAAQMAAQTAARKAAESGLRQVEVLVKGPGSGREAAIRSLQASGINVTAIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CEP1_HHV11
Sequence: MAAATADDEGSAATILKQAIAGDRSLVEAAEAISQQTLLRLACEVRQVGDRQPRFTATSIARVDVAPGCRLRFVLDGSPEDAYVTSEDYFKRCCGQSSYRGFAVAVLTANEDHVHSLAVPPLVLLHRFSLFNPRDLLDFELACLLMYLENCPRSHATPSTFAKVLAWLGVAGRRTSPFERVRCLFLRSCHWVLNTLMFMVYVKPFDDEFVLPHWYMARYLLANNPPPVLSALFCATPTSSSFRLPGPPPRSDCVAYNPAGIMGSCWASEEVRAPLVYWWLSETPKRQTSSLFYQFC
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
What are the official names of this protein?
Cytoplasmic envelopment protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: MURC_CHLP8
Sequence: MELGRTRNVHIVGIGGAGMSAIAELLLKSGFSVSGSDLASGEVIDKLRELGAVVWQGHEAEHVGMSDVVVYSSAVRPESNVEIQAAEKQGIPVIKRDEMLGELMRYKVGICVSGTHGKTTTTAMIATMLLESGQSPTVMIGGVSDYLKGSTVVGEGRHMVIEADEYDRAFLKLTPTIAVVNSLESEHMDTYGTMDNLRDSFAAFANKVPFYGRVICCVDWPEIRSLISRLNRRYTTFGIEEPADVMASDLEACEGGSVFTVEAFGESYPGVRLGVPGRHNVLNALAAFSVGLEIGLPPEKIIAGLGAYTGMRRRFQMKFKGGNGLLVVDDYAHHPSEVKATVKAARHGWKEHRIVAVFQPHLYSRTSEFAVEFGWALSRADAIYVAGIYPSRERTEDFPGVTGELVAEAARKAGAKEVTFEPDSEQLLDSLRQEAGPDTLILFMGAGDITHLATRFASMCADEGTATGAAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_RHOPB
Sequence: MIQHPTDTPEVAADAAAEPERAAGAAGATPQPSQDAVEPAADVDAATASLAAEDDDEPVLPQVPEEAGDEVAAGPLAIGRSAIAQAVRLAPTSPGVYRMLNAASDVLYVGKAKNVKKRLASYARPTGHVVRISRMIAATVSVEIISTATETEALLLEANLIKQLRPRFNVLLRDDKSFPYILITGDHWAPQIIKHRGAQSRPGRYFGPFASVGSVNRTITALQRAFLMRSCTDAFFESRTRPCLLYQIKRCAGPCTGEIDFPGYTALVREATDFLSGRSRLVKQELAGEMEKASAELEFETAALYRDRLAALSAIQSQQGINPRTVEEADVFAIHQEGGYFCVEVFFFRTGQNWGNRAYFPRAEKTFTVEEVLAAFLAQFYDDKAPPKQILLSHRIEECELLAEALCIKSGHKVEILTPQRGEKKELVGHALTNAREALGRKLADTATQTRLLQGLVTTLKLPHTPKRIEVYDNSHIQGTNAVGAMIVAGPDGFIKNQYRKFNIRSEGITPGDDYGMMREVLERRFKRLLAPPPEAEAGKPKPDDEVPQWPDLVIIDGGRGQLNAVQEIFQALGLSTVTLMAVAKGPDRDAGRETLFMPDRLPIKLEPRDPVLYFIQRLRDEAHRFVIGSHRKLRKKDIREAGLQEIPGIGPSRKRALLHHFGTLKEIERASLGDLGKVPGISAESAKRIFDYFHPQPG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_AERS4
Sequence: MSDYKHTLNLPETEFPMRGDLAKREPNMLKRWYDQDLYGAIRRAKAGKPSFILHDGPPYANGSIHIGHSVNKILKDVIIKSKGLSGFDSPYVPGWDCHGLPIELKVEGMVGKPGEKVSAAEFRAECRKYAKTQIEAQKTDFIRLGVLGDWEHPYLTMDFGTEANIIRSMAKIVENGHLHKGSKPVHWCTDCGSALAEAEVEYYDKNSPSIDVRFKAVDEATVAAKFDCPEGHLGKGPISAVIWTTTPWTLPANRAIAMHADLDYALVQVEGEHPERLILAAELVKDVMDRAGIEKFHNLGYTKGVALELLRFNHPFYSFDVPVVLGDHVTLDAGTGAVHTAPGHGQEDFVVGQKYGLEVANPVGSNGVYLPDTELFAGQHVFKANAAVVEVLTERGALLHHMVFNHSYPHCWRHKTPIIFRATPQWFISMEQKGLRQRALEEIERIEKDGITQHGQSGWVPAWGKNRIQAMVENRPDWCISRQRTWGVPISLFVHKETQQLHPESVRLMHEVAKRVEQSGIQAWWDLDKAELLGSDADMYDKVPDTLDVWFDSGSTHSSVVDARPEFNGHSADLYLEGSDQHRGWFMSSLMIGVAMKDKAPYNQVLTHGFTVDGQGRKMSKSIGNVVSPQDVMNKLGADILRLWVASTDYTGEMTVSDEILKRSADAYRRIRNTARFLLANLNGFNPATDMVAAADMVVVDRWAVGRAKAAQAEIVTAFEEYNFHGVTQKLMQFCSIEMGSFYLDVIKDRQYTAKADSLARRSCQTALYHIAQAMVRWMAPIMSFTADEIWALLPGERSEFVFTEEWYDGLFGLDAGEQMDDAFWAEILTVRGEVNKALEAARGEKRIGGSLQAELTLFAKPELAERLNALADELRFVLLTSKAKVVTADTAPEGSVATERADLWLSVAQSAAAKCDRCWHHVEDVGTIAGHEEICGRCATNVEGDGETRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTP_MOUSE
Sequence: MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT
What is the function of this protein?
Involved in the specification of hypothalamic neuroendocrine cells.  Specifically required for the specification of diencephalic dopaminergic neurons of the A11 group.
What are the official names of this protein?
Homeobox protein orthopedia.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y034_PYRHO
Sequence: MKKVKSLFLLVLGNTEISTIPGISVAGATPELTKITPVADAEYLFYEKPLTIDTIPVTPEGHPTPAIITKAARELSNFPILVVRGGTYLAPLIPHVHISNVVGRDFRREPALPEVEVIIERAKLLGKELEKIANEIVIGESTPGGTTTAQAILWALGYEAKTSSASPENPQELKEKVIKEGFKRVGIEKGGLKDKPLEALKEFGDPMIATVLGLSLGFGGDVVLAGGTQMLAVSALLKSLGEDLSRFMIATTRWVVEDPSATFIETAREIGIISYVAELDFSKSKFKGLRDYERGYVKEGVGAGGATWLAVKAGYSPEDVSKKVEELYERLMGLR
What are the official names of this protein?
UPF0284 protein PH0034.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: ECTB_VIBCH
Sequence: MDIFKHHESQVQSYANHFPVLFGTAKGSWLYSQQGDAYLDFLSGAGALNYGHNNAVLKQALLEYIERDGLTHGLDMHSEAKAHFIQALQTHILEPRGLNYKLQFTGPTGTNAVEAALKLARKVTGRHNVVTFTNGFHGCSLGALAATGNQHHRQGAGLALSGVYRVPYDGYAGVDGLTLFETMLQDNSSGLDKPAAVLLETVQGEGGLNVASDAWLQRVQAICRAQQILLIVDDIQAGCGRTGTFFSFEPSGIEPDMVTLSKSLSGYGLPMALVLFKPEWDQWKPGEHNGTFRGNNHAFVTATRALEAYWANQDFQTHIAARSEQVTQALLQCLSRYPTLFSGLKGRGLMQGLACHNGDIARDIAALCFQKGLIIETAGAEDEVLKVFCPLTITEADLAHGLTIIERVLLE
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: BPT_BURCM
Sequence: MTHPTELPLSPLSALQFYATAPYPCSYLDGRIARSQVATPSHLINSDIYTELVKAGFRRSGVFTYRPYCDGCRACVPVRVPVGAFTPSRTQRRMWKRHRALVATVSPLHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFRDLDAPAGEPGKLRMVSMIDILGDGLSSVYTFFEPDDQHTSYGTYNILWQIEQAKSLGLPYVYLGYWIRESPKMAYKANFHPLEGLLDGRWKVLDPDRVELPPVDAALARAPLPGGHSGSG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NEOSM
Sequence: MLAPKKLKHKKFRKVRFSDASARGSGLAFGEYGLKAIGSARLNGRQIESARRVITRIVSKAGKLWINVFPGIPLTRKPTDVRMGGGKGSVDSYIFAISPGRVLFELGGVDREKAKLALCKASAKLPFSTKFVERVSCEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ATPB_COCNU
Sequence: MRTNPTTSSPVVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRVLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NLTP_MALDO
Sequence: MASSAVTKLALVVALCMAVSVAHAITCGQVTSSLAPCIGYVRSGGAVPPACCNGIRTINGLARTTADRQTACNCLKNLAGSISGVNPNNAAGLPGKCGVNVPYKISTSTNCATVK
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: APOA1_BALAS
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDDPQSSWDRVKDFATVYVDAIKDSGRDYVTQFEASALGKQLNLKLLDNWDSLTSTFAKVREQLGPVTREFWDNLEKETESLRQEMNKDLQEVKQKVQPYLDEFQKKWQEELQIYRQKVAPLGEELREGARQKVQELQDKLTPLAEEMRDRARAHVETLRQQLAPYSDELRQRMAARFEMLKEGGGSLVQYHAKASEQLKALGEKAKPALEDLRQGLLPVLENLKVSILAAIDEASKKLNAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_DEIRA
Sequence: MPGIAIVGAQWGDEGKGKIVDFLAPEAEYVVRYQGGANAGHTVNAKGKTFKLNLLPSGVLHEGATSILGDGMVIDPEKFIEERRNLMEGGLNPRLKISDRAHIVLPHHKYVDGRKDFVGTTGKGIGPAYADRARRVGIRFGDLLDEGVLRERIERLLEAKPNSTRDAGWATVEDGLKSLAPIREQLAPFIADTGSELRQAIKDGRKVLFEGAQATLLDLNYGTYPFVTSSHPTVGGILVGTGVNHKALHRVYGVAKAFNTRVGHGPFATEVHDEAGILRLRGDGSQPWDEYGTTTGRPRRVGWLDLELLKYAVDVNGLDGLVINKMDILGGLDEIPVCTGYDEGGQPVFKKMKGWSSTDGVTSRATLPKEAQAYLDLIEDTVQCPVVIFSAGPEREKTYGEVHWG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y484_RICPR
Sequence: MKNVISLTDAAAKQVKLLIEKRAKPTFGIRVGIKSGGCAGQTYYVEYADNKNQFDEVVEEKGVRILIDPKTLMYILGSEMDYVETNFKSQFTFTNPNEKANCGCGKSFSV
What are the official names of this protein?
Uncharacterized protein RP484.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ERFD_CANAL
Sequence: MNETKTDSTVNPDQSSQELVFFNYHEYLVPGSDDTSLVINHFPNIHTDLSSSTFKETRIIRIPRVYHTVQFPDLIPQFSCYYPGSEPGAITSTQLMSGSFDDNSFNESSSIPSLENIISRSEFENIVSLVNESLAVAFNPMSKRMLLENLLDLLSGGLFLSLLNFLGIYSFTKRKLMELESQIDSINQINEKKGVDFKIISPRVTGYLSLDFQITKPR
What is the function of this protein?
The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins.  Palmitoylates RAS2, which is required for its proper plasma membrane localization (By similarity).
What are the official names of this protein?
Ras modification protein ERF4.
What is the protein family that this protein belongs to?
Belongs to the ERF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RL20_THEYD
Sequence: MPRAKGGFKTRRYHKKILSMAKGYYSGRRRCYKVAAKAVEKALEHSYRDRRLKKRDLRSLWITRINAAVRMFGLTYNQFIDGLKKANISLNRKALADIAYNDINVFGELVEKVKPFVKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL23_AERHH
Sequence: MIREERLLKVLKAPHISEKSTMVAEKQNTIVFKVAVDATKAEVKAAVAKLFEVEVETVRTLNMKGKTKRAGARVGRRSDWKKAYVTLKAGQDIDFMGAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NTPPA_CARHZ
Sequence: MKIYLASKSPRRQELLKKIYSRFEIIPPEVKEEVYSLNPMELALTLSRQKAENVAAKIKEGVIIAADTVVAVEGKVLGKPRDEEEAYFMLKTLSGREHEVYTGVTLMELPQKREKSFVEVTKVWFYPLTDEEIKSYIDSREPFDKAGAYGIQGKGALFVAKIEGCYFNVVGLPVARLYRELREWGY
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_RHIME
Sequence: MKHVHIFTDGACSGNPGPGGWGAVLRYGDVEKEMSGGEAETTNNRMELLAAISALNALRQPCEVDLHTDSKYVMDGISKWIHGWKRNGWKTGDRKPVKNGELWQALDEARNRHNVTWHWVKGHAGHPENERADELARKGMEPFKKARRADAVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.