PharMolix/UniProtQA huggingface dataset:
Protein: NHAB_ALIF1
Sequence: MSISLGNAFIKNFLGKAPDWYKIAILSFLVINPLVFFFVDPFTAGWLLVVEFIFTLAMALKCYPLQPGGLLAIEAIAIGMTSPEQVKHELVANIEVLLLLVFMVAGIYFMKQLLLFIFTKILIGIKSKTALSVAFCFTAAFLSAFLDALTVIAVVISVAVGFYAIYHRVASGQGGSQTHDHTCDSDVDELTREDLEDYRAFLRSLLMHAGVGTALGGVMTMVGEPQNLIIADQAGWMFGEFIIRMLPITAPVFICGILTCIAVEKLGICGYGAKLPENVRKILEDYEAEERKNRTNIDNAKLIIQGLIAVWLIVGLALHLAAVGLIGLSVIILATAFTGVIEEHSMGKAFEEALPFTALLAVFFAVVAVIIDQELFKPIIDAVLAVEDKGAQLALFYVANGLLSMVSDNVFVGTVYINEVKAALMDGVITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIQLSYGRMVWMALPYTIVLALVGMFGIIFFLEPMTAMFYDLGWIAPGTIESATSAISSGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVA_ANAMM
Sequence: MIGTLSGTVEEVVCSNRIILCVGGVGYLVQLPGRVLSGCQHGDHVRLYIETYVGRDGVSQLYGFANREEQNCMRMLIKVSGVNYKTAMAILDVLTPEQVFSAIVSEDRAALKVGGVGEKLISRIISELTPQVQKFELNRFAATTRTDSEAVAALLSLGYERTAALGALQKVGVCDSTEDAVRRALLELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL18_FRATN
Sequence: MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIANRCKEKGISQVAFDRSGYKYHGRVKALAEAAREHGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: NUSB_STRP8
Sequence: MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTGEDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DAPB_DESHY
Sequence: MKKIRVFVSGAGGKMGREVVRTILDQEDMQLVGASDARQQGRDIGELLAMAPLGIEITGPLEVAHLKETRADIMVDFTNPQSVLKNAKCALAAGVVPVLGTTGLDEADISEIRDLVDQTKVGAFIAPNFAIGAILMMRFAQEAAKYFPHVEIIELHHDQKLDAPSGTALKTVEWISEVRKPLVQGHPNEYEKIKGSRGGDVDGIHIHSVRLPGFIAHQEVIFGGLGQALTIRHDALSRETYMPGIMLAVRKASQLSNLVIGLENFLE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SALAI
Sequence: MRCPYCRHPDSRVVDSREADDGQLIRRRRSCPECGKRFTTVEEAVLAVVKRSGVTEPFSRTKIIGGVRKACQGRPVDDDSIALLAQKVEETVRAKGAAELPSHEVGLAILGPLRDLDEVAYLRFASVYRSFESLADFEREIETLRTAAQTRGGG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: BCP_HAEIN
Sequence: MNPLSVGNQAPAFTLLNQQEKFVSLSDFRGKKVLIYFYPKALTPGCTTQACGLRDSKSELDVLGLVVLGISPDAPKKLAQFIEKKELNFTLLSDPDHQVAEQFGVWGEKKFMGRTYDGIHRISFLINESGTIMQVFDKFKIKDHHQMIIDYLRSL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Putative peroxiredoxin bcp, Bacterioferritin comigratory protein homolog, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin Bcp.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
Protein: MEND_ACAM1
Sequence: MTLDFRNVNMLWSSIIAETLSRLGLTTAIICPGSRSGPLAVAFAQHPDIEAIPVLDERSAAFFGLGIARRKGLPVVLVCTSGTAGANFYPAVIEAEASGVPLLLLTADRPPELRHCQAGQAIDQVKLYGHYPRWQVELALPSTHPEMLAYLRQTCVYAWEQSQRPVPGPVHLNIPFRDPLAPISDLETESLAATFDIDQFFAAVHPLPSVQISLDLQTTNVYLDQWMSCDRGLIIAGPAQPDTPEHYCLAIAQLAHILGWPVLAEGLSPLRNWADRNSYLISTYDLILRNPTIASQLQPQQVISIGALPTSKVLRVWLTQSRAQTWVVDVSDHNMDPLHGLSIPVRISVEGLITSIPAAKKEHCQPLTAYAKSWLNANHSVRTLINRAMQKQSELIESKIAWLLSQILPPRTPLFIANSMPVRDIEYFWQPGTLHIQPYFNRGANGIDGTLSTALGMSHRQQSSVLLTGDLALLHDTNGFLLQDYWQGHLTIIVVNNGGGGIFQMLPISAFDPPFERFFRTPQQVQLKHLAATYQAKWTLIQSWAHLQQALNPLPESGLHILEISCDCQNDTQWRRIFFKECVKSL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ATPL_YERPY
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAGP_PROMH
Sequence: MSSTYFHSSLLAATLFSVTLTAPAFASENTQNTPQTITTKKPQPAENTFSEKNEESYWGKFKRNLTQTWDNDQYNYYLPVWTWHNRFTYDKEKTNRYNETPWGFGMGKYRYDNEGDWHGLYAMAFMDSNNRVQPIMGYGFEKMWYPGGDREGFRMGAGFTLSVTARHEYNYIPMPLPLPLVSVGYEHLSLQATYVPGTYNNGNVLFAWLRWQ
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ACYP_SALPA
Sequence: MSNVCIIAWVYGRVQGVGFHYTTQHEAQRLGLTGYAKNMDDGSVEVVACGDAAQVEKLIKWLKEGGPRSARVDKILTEPHSPRETLTGFSIRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL5_ECO57
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRP_SCHPO
Sequence: MTEQIKKTFLKAKEENKNVLVTFVTCGFPNVDETIKIMQGLQNGGAGIIELGIPFSDAVADGPTICKGNEIALKNNITLEKVFETVKLARDAGVTIPIILMGYYNPIFSYGDAKTIQKAKEVGANGFIIVDLPPEEAVGFREECKKQGVSFVPLVAPSTTDRRMELLASVADSFIYVVSRMGSTGSSATGVINTALPQLCQRVRKFAGDTPLAVGFGVNTSEHFHQVGSVSDGVVVGSKIIDLILKAEPGTAATVVEEYCKYLTKEDPSAPVPKQFQSGGSVATAPPAAVVEPINEMYLPQKYGMFGGMYVPEALTQCLVELESVFYKALHDEKFWEEFRSYYEYMGRPSALDYAKRLTEYCGGAHIWLKREDLNHGGSHKINNCIGQILLAKRLGKNRIIAETGAGQHGVATAICAAKFGMKCTIYMGAEDCRRQALNVFRIRLLGAEVVPVTSGTQTLRDAVNEALKAWVEQIDTTHYLIGSAIGPHPFPTIVKTFQSVIGEETKAQMQEKRKKLPDAVVACVGGGSNSIGMFSPFKADKSVMMLGCEAGGDGVDTPKHSATLTMGKVGVFHGVRTYVLQREDGQIQDTHSISAGLDYPGVGPELSELKYTNRAEFIAVTDAQCLEGFRALCHLEGIIPALESSHAVYGGMELAKKLPKDKDIVITISGRGDKDVQSVAEQLPILGPKIGWDLRF
What are the official names of this protein?
Tryptophan synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpB family.
Protein: COG1_PARCM
Sequence: IVGGQEASPGSWPXQVGLFF
What is the function of this protein?
This enzyme is a serine protease capable of degrading the native triple helix of collagen.
What are the official names of this protein?
Collagenolytic protease 28 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: RPC3_AJECN
Sequence: MSQYAAELCKLLITDNFGELYAPLPRIVQNTRLSPRQVRHGLAVLIQQRLIYHYTSLDDGIAYYEASWMTAYNLVRSGRILQLVEEKLGKYVAKVLSTILYHGHVRISYLETLPELRPQVSSKAGKLVAANGLNGIHSDEEEEEEDAHVTDQGEQEEYASGRPENSVDSDYGKRSASQLHPALRSLAAYGYIMRVRDAHFQSPADLVEDAERAVSSRSDVRGLKGKKFQEAIDAGVETYIKEKTDGTIPQGPLAGALPRGIKRRAGQLATNSSSKRVKLEHLPEGDEDIDDDDFYGDDYVDGDNTLMDPNMIISVNYQKFEVALRNRRLARLAEQCTSRVTSQVYEALLGRIELKTPACRKQPERVPEGEENEQYSVAIPLHTILDDIDPDLDLSESMAGVDPANLLSNGHMGLNGDGNGDDDDDESTGASTGIWNRRRNRVYELEQHLSLLAQEPNIFSTRSMQSGMITWAVEFRHLARRLRHLEIERIIESRFGTIAVRVIRVLAAKGKLDEKRLQEISLMASKELRQVLARMEAAGFVDLQEVPRDAQRQPSRTMYLWFFDLDRVARMVLEDTYKCMSRCLQRIGVERNKLKLFLEKTERTDVKGNEEKYLSPAELKTLKEWRDKEALLLGEVGRLDELVSVLRDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE3_RHIE6
Sequence: MNLTPREKDKLLISMAAMVARRRLERGVKLNYPEAIALISDFVVEGARDGRPVAELMEAGAHVIGRDQVMEGIAEMIHDVQVEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_HERAR
Sequence: MQFKRLSDLIARNELKGKRVFIRADLNVPQDGKGNITEDTRIRASVPAIRQALQAGAAVMVTSHLGRPVEGEFKPADTLAPIAQRLSELLGQPVALKQDWVDGVDVAPGQVVLLENCRVNKGEKKNDDVLAKKIAALCDVYVNDAFGTAHRAEATTHGIAKYATVACAGPLLAAELDALGKALHQPASPLVAIVAGSKVSTKLTILKTLADKVDNLIVGGGIANTFMLAAGLKIGKSLAEADLVGDARAIMDMMAKRGASVPIPVDVVCAKEFSPTAIATVKDVADVTDDDMILDIGPKTADILAKQISQAGTIVWNGPVGVFEFDQFANGTKTLAHAIAESSGFSVAGGGDTLAAIAKYDIADKIGYISTGGGAFLEFLEGKTLPAVEILEQRATS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_PROMP
Sequence: MGTANLHDSTNKPLYGERIIEESNIICFENPNKKRIYEISIELPEFTCKCPFSGYPDFAKLNIYYQPNMKVYELKSLKLYINKFRDLKISHEEVVNRIMDDLLKAAVPHWIHLNADFNPRGNVSMKLDIYSGQKRN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGP3_ALLVD
Sequence: MTMKRLLLVSTLAGASALATLPANAFWGWNPFGWGGGPWDGPWGGGPWGSPWYGGYPYHGGYYPYGLYGVPYGWGAPVYGYPGYVYPGYAYPAPTQPSTKSQ
What is the function of this protein?
Structural protein of the sulfur globules, which are intracellular globules that serve for sulfur storage in purple sulfur bacteria.
What are the official names of this protein?
Sulfur globule protein CV3.
What is the protein family that this protein belongs to?
To T.roseopersicina TR2.
Protein: GCSPA_ANAD2
Sequence: MRYHPHTPDDVRAMLDVVGAERVDDLFRSIPQALRLDRPLDLPPAADEIALFSELRRLAARNETAHPPFVGAGCYPHHVPPVVDQLLLRGEFFTAYTPYQPEISQGTLQALFEWQTFVCLLTGMDVSNASMYDGATATAEAALMAGRITGRDKVVVSAALHPEYRKVLATYLRSTGDEIVTVPFGADGRTDLAALAQAVDGRTACVILGYPNFLGVVDALPEAAALARAAGALTVAATAEAVSLGLLQAPGALGADVAVGTFQSFGNPMSFGGPAPGFFATREKSLRQMPGRVAGATVDKQGRRGFVLTLSTREQHIRREKATSNICTNSGLCALASTIHLSLLGKRGLAELARLNHGRARMLRDAMERAGCRPVFSGPYFNEQVFDVGDAEAVVAKLAKRGIVAGAPLARWYPDAPHAKGALLCAATELHGPELIQLFASTVRS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: TPIS_ACTP7
Sequence: MARRPLVMGNWKLNGSKAFTKELIAGLKAELADVKGCDVAIAPPVMYLAEAEAALAGQSVIALGAQNVDVNVQGAFTGDISTEMLKDFGAKYIIIGHSERRTYHKECDTFIAKKFAALKAAGLVPVLCIGETEAENEAGQTEAVCAKQIDAVIDALGVEAFNGAVIAYEPIWAIGTGKSATPAQAQAVHAFIRGHIAAKSQAVADQVIIQYGGSVNDANAAELFTQPDIDGALVGGASLKAPAFAVIVKAAEKAKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_FRATF
Sequence: MSLMKEMLSAGVHFGHKKAFWNPQMKEYIFGINHGVHIINLEKTVPLFQDAVNFVGKTVANGGKILFVGTKRQAQDIVEAEAKRCGMPFVSHRWLGGMLTNYKTVRQSIKRLAQLEKMREDGTLESLTKKEMLQNIRTIEKLEKVLGGIKEMGGLPDAIVVIDGNKEHIAIQEAQKLGIKVVAIVDTNSNPEGIDYIIPGNDDAVKSISFYMKKFADAVIDAQGLDRAVEAKADEAAQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NTPTH_THEMA
Sequence: MKILITGRPGVGKTTLIKKLSRLLQNAGGFYTEEMREGEKRIGFKIITLDGEEGILARTDLPSPYRVGKYYVNLKDLEEIGVRSLERAFQEKDLIIVDEIGKMELLSRKFREVVEKIFDSEKDVIATIKKSSDPFVEKIKNRNDVVIFELNEKNRNSLLNEILSVLKFNRGEKQ
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: EC1_WHEAT
Sequence: MGCDDKCGCAVPCPGGTGCRCTSARSGAAAGEHTTCGCGEHCGCNPCACGREGTPSGRANRRANCSCGAACNCASCGSATA
What is the function of this protein?
Binds 5 molecules of zinc.  May have a role in Zn(2+) homeostasis during embryogenesis.
What are the official names of this protein?
EC protein I/II, Zinc metallothionein class II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: ADA10_HUMAN
Sequence: MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR
What is the function of this protein?
(Microbial infection) Promotes the cytotoxic activity of S. aureus hly by binding to the toxin at zonula adherens and promoting formation of toxin pores.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Cell projection, axon. Cell projection, dendrite. Cell junction, adherens junction. Cytoplasm. Note=Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011).
Protein: H2A2_XENLA
Sequence: MSGRGKQGGKTRAKSKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAWERLPEITKRPVLSPGTCNSLCNDEELNKLLGGVTIAQGGVLPNIQSVLLPKKTESSKSTKSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RPIA_FRATN
Sequence: MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYVARQIVKLGGQPVYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: FIEF_ECO55
Sequence: MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SBMA_ECOLI
Sequence: MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQIPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLVEVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVSHYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIAFLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHELDGDKIQEVTHTLS
What is the function of this protein?
Uptake of antimicrobial peptides.  Required for the transport of microcin B17 (MccB17), microcin 25 (Mcc25) and proline-rich antimicrobial peptides (such as Cathelicidin-3 and Arasin 1) into the cell.
What are the official names of this protein?
Peptide antibiotic transporter SbmA.
What is the protein family that this protein belongs to?
Belongs to the peptide uptake permease (PUP) (TC 9.A.18) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_GEOTN
Sequence: MANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGGIDIGDEPLLVQIRQQAEIAIDEADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNKIDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVARHFPKDHGQEYEEDVIKFCLIGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIYESTEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVEKDDKTMVEFERKIRDHFPFLDYAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLNEVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIIARPRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: Y2909_STRGG
Sequence: MADSSFDIVSKVERQEVDNALNQAAKEISQRYDFKGTGASISWSGEKILMEANGEERVKAVLDIFQSKLIKRGISLKSLDAGEPQLSGKEYKIFATIEEGISQENAKKVAKIIRDEGPKGVKAQVQGDELRVSSKSRDDLQAVQALLKGQDFDFAVQFVNYR
What are the official names of this protein?
UPF0234 protein SGR_2909.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.