PharMolix/UniProtQA huggingface dataset:
Protein: LSRA_PHOTE
Sequence: MLHNNTAVPPLLEVSGISKQFSGVMVLKHIDFTLLPGQIHALLGGNGAGKSTLMKIIAGIEQPDKGSIKIDGNNVSHLNPTKAHQLGIYLIPQEPLLFPNLSVQENILFRLPKHQADKARMKHLLELLGCQLDLNANAGSLNVADQQLVEVMRGLIRNSNVLILDEPTASLTPAETERLFTQLRELQQQSVGIIFISHKIPEIHQLADQVSVMRDGGIALSGKTCDYTTDDIIRAITPAAKNKPLTDTEKRWSELNDNPQKTSSDLPVLTVTDLNGEGFRNITLSVKPGEILGLAGVVGAGRTELAETLYGLRPVLSGEIKLKQCPITRLKTVQRLKQGLVYLPEDRQSSGLFPDSSLSWNICSLTHNNRTFWVHPTYDATVVERYRQALNIKFSHINQPVKTLSGGNQQKILIAKCLEAHPAVLIIDEPTRGVDIAARNDIYQLIHNIAQQQVAIIFISSDLDEVVQMADRVLVMHQGEINGELTKQQIDVDTIMHIAFGEHKSQQAVSTIKTDKAASC
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Autoinducer 2 import ATP-binding protein LsrA, AI-2 import ATP-binding protein LsrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOC_BURO1
Sequence: MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTFGDGAYDGPRFAAVSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
Protein: METE_BURM7
Sequence: MTTAHILGFPRIGAQRELKFALERYWRDGASADAERALVDTGRALRAEHWRIERDAGLDCVTVGDFAWYDHVLTTLAHVGGLPRRFGFDARALTLADYFAAARGNAAQPAMEMTKWFDTNYHYLVPEYSPATTFGPGVEWLFDEVREARALGYRAKAALVGPLTLLWLGKARDGLVERLALLPRLVPAYRALLARLREAGVDWVQIDEPIFSLDLPDAWRDAARPTYEALAPGAPKLLVATYFDDASEHAALLKALPVAGLHVDLVRADAQLDAFVADYPADKVLSCGIVDGRNVWRNDLDRSLARLAPVRDALGERLWVATSCSLLHVPVDLAHEPRLDEELKTWLAFAAQKTREVAALRDALVKGRAAVAAEFDDAAVVAAARRTSARIHNPLVKRRVAALTDADARRASAYSVRAAAQRARFGLPLLPTTTIGSFPQTPEIRRARAAFKQGVLDHLGYLEAMREQVRIAIDKQLAYGLDVLVHGEAERNDMVEYFGELLWGFAITSNGWVQSYGSRCVKPPLVYGDVYLPEPMTVGWASYAQSLSAKPVKGMLTGPVTMLQWSFVRDDQPRATTALQIALALRQETLDLEKAGIGMIQIDEPALREGLPLKARERAAYLDWAVRAFGIAASGVADDTQIHTHMCYSEFGDILPSIAALDADVISIETTRSNMELLDAFETFDYPNEIGPGVYDIHSPRVPDADEIERLILLALERIPAQRLWVNPDCGLKTREWRQVDAALAAMVDAAKRVRQKVEEAAPA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: DCUP_XANC8
Sequence: MLKNDRLLRALRRQPVDRTPVWLMRQAGRYLPEYRATRARAGSFLGMAKNPDIACEVTLQPLERFPLDAAILFSDILTIPDAMGLELYFVEGEGPKFRHPVRDADAIHRLGVPDMETELRYVMDAVRLIRRELDGAVPLIGFSGSPWTLACYMIEGGGSKEYARIKAMAFNAPQLLHHLLSTVTDAVIAYLSAQRAAGAQALQVFDTWGGVLSPAMYREFSLPYLTRIAQELERGSGEERTPLVLFGKGNGAYVSELAASGAEAVGVDWTISLADAAERAGGRVALQGNLDPATLYGSPDAIRSEVGKTLDSYAYGNGGSREGHVFNLGHGMSPDMNPDHVGVLVEAVQTLSKR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_RICAH
Sequence: MEIILIKPVRKLGKIGDMLKVADGFGRNYLLPQKLAIRATEPNKELIVKQKHEFEAKDKQIREEVEKINALIKDQKLVFIRQASDDGKLFGSVTNKEIADKLSKNVSYNISHSNIILDKQIKSTGVYTVEIRLHAELNDIVTVIVARSESEAQDYLREKKTETSEDLAESA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CYSD_SHEWM
Sequence: MSTHQTHLKQLEAESIQIMREVAAEFDNPVMLYSVGKDSSVLLHLARKAFYPGKIPFPLMHVDTNWKFKEMIEFRDQMAEKHGFDLIVHKNPRGLEMNISPFTHGSAKHTDIMKTEGLKQALDAHGFDAAFGGARRDEEKSRAKERVYSFRDNKHRWDPKNQRPELWNIYNGKVDKGESIRVFPLSNWTELDIWQYIYLEGIEIPSLYLATERPVVERDGTLIMVDDERMPLEADEDVQNKMVRFRTLGCYPLTGAVESQAQTLPEIIQEMLLCTTSERQGRVIDNDSAGSMEKKKIEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: COAD_BORBU
Sequence: MRVAVFPGSFDPITWGHIDLIKRSLAIFDKVIVLVAKNKSKKYFLSDIERFSLTKDVISSLNFSNVLVDRYSGFIVDYALINSIKFIVRGIRAFNDFDIEFERYLVNNKLNFEIDTIFLPSSAEHLYVRSDFVKELMLKKDVDLSNFVPELVFNRLKSKFIDK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_ECODH
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPETAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPCE_DROME
Sequence: MEKRLSDSPGDCRVTRSTMTPTLRLDQTSRQEPLPQQPDNGPAAAPGKSKSPTPLPGKSQAAQHHQFRAPQQQQGPKNRNKAWSKRQHKAGGKHNPSACVGASSGQAQSTGSSVIAATLLPTAASAHKADLENIQNIHNKNLTAGGGVNHHGNAGTAHHGGGGGAGAHHAAAGGHHHHHNTRLAQNAAAGGASGGGTIQMHKKMLRGHHHHVLCAGNNANHTCCLVTGCNGSSIGGVGVAGSGGATASAGGGGASCKEAQSCKDTSSLSGNSSIAGSAGAGNAVHYCCGRSKFFLPEKRLRKEVIVPPTKFLLGGNISDPLNLNSLQNENTSNASSTNNTPATTPRQSPITTPPKVEVIIPPNIHDPLHLLDPVDSMEYEKQLTSPMKRAGPGGGMLHHRQHHYRTRKNRKRRRFDSNNTSHAGDEGGVGSELTDEPPLPAATSSLAASPVAAPLNVGGSLLLSESAAPAPGETAEMGQQQEQAHVHSPQSASTTTTAAEMPTPTPTSAAAATATAEHKEQSAPAPTATSSPQRQQQHVAAAAEELPTPETSAAAETPAEEMLLSCSATSASLVASTLAERRASRDLRLDLSSTCYGVGGTGLSFGGSISSSVGSSFGGGGRKRKISESSTSQKSKKFHRHDAMDKIVSPVVPQPGAWKRPPRILQPSGARKPSTRRSTSVSESELLSPVEEQPPKQLPLIGVEIPRDDTPDLPDHGLGSPLSTTSGATSHTAGEQDSLAGVDISMGDTLGSGVVGKAPLTSSLMLEPAKIPPIKMLPKFRADGLKYRYGNFDRYVDFRQMNEFRDVRLQVFQRHVELFENKDILDIGCNVGHMTITVARHLAPKTIVGIDIDRELVARARRNLSIFVRIPKEEKLLEVKAEPTVDAKANIAVKDETSGAAHKKTRRGKRRRKVHQGIHHHHHHHHDLEQLQQQQKLNSLLVKPHEFFPISFPLTYGRIPRILSSSKSPNMLGNKNQFPANVFFRHTNYVLKDESLMASDTQQYDLILCLSVTKWIHLNFGDNGLKMAFKRMFNQLRPGGKLILEAQNWASYKKKKNLTPEIYNNYKQIEFFPNKFHEYLLSSEVGFSHSYTLGVPRHMNKGFCRPIQLYAKGDYTPNHVRWSDAYYPQTPYEAYRGIYATLPVHRMGGGGSSAGGSNSGHAQMLHLSSSSRSQNYDTPHYAGSASGSASCRQTPMYQPTYNPLETDSYQPSYDMEYLNHMYVFASPLYQTVWSPPASLRKSSSHTPVFGSVRDAELDGDGSGGGGSGGGSYHRHVYPPNDDTCSPNANACNAFNSIRDADTDDSNQLPGGSRRHVYATNCGESSSSPQVNHHDAVGEFVDGLMDDEQKSSTGGGTGGAAYCDLSDA
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it (By similarity).  Required for dorso-ventral patterning in oogenesis and for anterior-posterior pattern formation during embryogenesis, possibly by binding and stabilizing 7SK RNA, thereby promoting formation of a repressive RNA-protein complex (PubMed:21262214).
What are the official names of this protein?
7SK snRNA methylphosphate capping enzyme bin3, Bicoid-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: PVK2_CRYKY
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, CryKy-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFPL_YERP3
Sequence: MAKANEIKRGMAVNLNGKLLLVKDIDVQSPSARGASTLYKMRFSDVRTGLKVEERFKGDENLDTITLTRRAVNFSYIDGDEYVFMDDEDYTPYNFKKEQIEDELLFIPEGGMPGMQVLTMEGQLLALELPQTVDMEIVDTAPSIKGASASARNKPAIMSTGLSIQVPEYISPGEKIRIHIAERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: CLSA_BUCAI
Sequence: MDIFYNLIKCLIFSTYWLLIANITFRVLIKRRNIPYSMSWLLTIYIIPFIGISIWFFFGELYLGKRQKKIANRIWSISNKWLHELKSCTYIFQIKNSEVATSIFQLCKNRQGLHGIKSKKIKLLTNTKKIMQILIRDIYLARKNIEMVFYIWKPGGMADDVAIALIDSAKRGIHCRLMLDSAGSIEFFQSPWVEIMRKSGIQVVEALKVNLLRVFLRRVDVRQHRKIILIDNYIAYSGSMNLVDPYLFKKSSEIGQWIDLMTRIEGPIATTMGIIYSCDWEIETGLKILPQLPNKKMLENQSNKNASIQVIASGPGFLKNMIHQALLTAIYSAKRELIITTPYLVPSEDLLEAICTAAQRGVEVSIIIPLYNDSILVKWASRVFFSELLEAGVKIFQFQKGLLHSKSILVDQQLSLIGTVNLDMRSLWLNFEITLVIDDSDFGRNLFCIQNKYISDSQLIDKKAWSMRAYWKRILEKIFYFLSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPE_ECOUT
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMDFADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLVGEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFINELVAIEWDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RL18_ECOLC
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL35_MYCTA
Sequence: MPKAKTHSGASKRFRRTGTGKIVRQKANRRHLLEHKPSTRTRRLDGRTVVAANDTKRVTSLLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FLIL_BORBU
Sequence: MPNKDDDNLDMGDSNVSRKGGLLPDIIIKILQILAIGIFTVAIMIIVSYFVSKMVVSQSGAPSDFPVFSNEYLGKPPMLIWYESIDEIRGNTLDVPPKTFVVKLALGYAENNVNILNELGRQKVRLKDIIREYFSQRTGQEIKNESQIKAEIKARINSILRNGEIKEIALTQIDIFDM
What is the function of this protein?
Controls the rotational direction of flagella during chemotaxis.
What are the official names of this protein?
Flagellar protein FliL.
What is the protein family that this protein belongs to?
Belongs to the FliL family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MDV1_EMENI
Sequence: MDKHRRDDSPSGLSDIVERDGLLGTGITSRHIEAFGRKVTSTAGHLMGPSGDPSTSTHYQNAMVDIHRELRRPSTQRKVFALAQTTPTDLVRSKLSTSEIQSRAISSLPDELLLNIPDDTSSYSLFEGFQATQNDHEYRKAHRRGRSKGKKLLKDKDGEQADPPSTLTELKKERDLLSRRMELMGVRKNMCSSEIVDIDNKIANFHRMRQIVLDRLAGLEMEEAELEHEVNEIDNKLDDMAEEEAAQAAQAAAAAAAATTAGSETHEEPASEDPAMDASFMSESIYQKLPSPRSLKHRSIRKRSMPVLHEHFAPGSEIKEFQAHTDVVTALDLDYPFGTMITAALDDTVRVWDLNIGRCTGFLEGHNASVRCLQIEDNVVATGSMDATVKLWDLSRARTTHRDNRVNKDEDDDAVSVAYSTSLEDCHVYSLDAHVGEVTALHFKGNTLVSGSADKTLRHWDLVKGRCVQTLDVLWAAAQASSLGNESQWRPSGRLPDASADFVGAVQCFDAALACGTADGMVRLWDLRSGQVHRSLVGHTGPVSCLQFDDVHLVTGSLDRSIRIWDLRMGSIYDAYGYDKPVTSMMFDTKRIVAAAGENVVKVYDKADGHHWDCGAGVGADETGPDPAIVERVRLKDGFLIEGRRDGIVAAWTC
What is the function of this protein?
Involved in mitochondrial fission.  Acts as an adapter protein required to form mitochondrial fission complexes.  Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
What are the official names of this protein?
Mitochondrial division protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MDV1/CAF4 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS5_HALWD
Sequence: MSQSQRNSDGWTPRTRLGRMVQDGDVTSMEQALNSGLPLKEPELVDQLLPGLDDEVLDINMVQRMTDSGRRVKFRCVVAIGNRNGFLGYAEGRDDQVGSAIQKAIDVAKLNLISVDRGSGSWEDSAGGVNSLTRNAEGKAGSVTVEVMPAPQGLGLAAAETVSNILELAGVEDAWTRSNGNTRTTVNLAKATYNALRNASQSRTPRRAAAKQREQEVSE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TRMD_BURP6
Sequence: MDEATQSAIQFDVVTLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLAKPLEAAIGAAKAAQAAQGVATSRVVMMSPQGAPLTHERVARMAAEPGVVLLCGRYEAIDQRLIDRCVDEELSLGDFVLSGGELPAMALMDAVVRLLPGVLNDAQSAVQDSFADGLLDCPHYTRPEEYEGVRVPDVLLGGHHAEIERWRRQEALRNTIAKRPDLIARARREKLLSRADEAWLASLAKEAKQAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_ECOLI
Sequence: MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA (PubMed:2040637).  DNA bound in the ring is bent 22 degrees, in solution primed DNA is bound more tightly than dsDNA, suggesting the clamp binds both ss- and dsDNA (PubMed:18191219).  In a complex of DNA with this protein, alpha, epsilon and tau subunits however the DNA is only slightly bent (PubMed:26499492).  Coordinates protein traffic at the replication fork, where it interacts with multiple DNA polymerases, repair factors and other proteins (PubMed:15466025, PubMed:16168375, PubMed:22716942, PubMed:14592985, PubMed:14729336, PubMed:26499492, PubMed:15952889).  Initially characterized for its ability to contact the alpha subunit (dnaE) of DNA polymerase III (Pol III), tethering it to the DNA and conferring very high processivity (PubMed:2040637).  Pol III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; it also exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication (PubMed:3519609, PubMed:2040637).  A single clamp can bind both Pol III and IV, allowing the repair Pol IV to access DNA when it is damaged and needs to be fixed, a process the replicative polymerase cannot perform; when DNA is repaired Pol III takes over again (PubMed:16168375).  Serves as a processivity factor for DNA polymerases II (PubMed:1999435, PubMed:1534562), IV (PubMed:10801133) and V (PubMed:10801133).  A shorter protein beta* may be important for increasing survival after UV irradiation, and stimulates DNA synthesis with increased processivity in the presence of core Pol III plus the clamp loader complex (PubMed:8576210, PubMed:8576212).
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to midcell position when chromosomes are condensed during DNA replication (PubMed:23994470).
Protein: KORB_ARCFU
Sequence: MKAEYADYLRTEMLPTIWCAGCPNGIVLASFIRAVKRGFERDKTVVVSGIGCSGRITQYLDFETVHTTHGRALAFATGIKLAKPELNVVVFMGDGDAVAIGGNHFIHACRRNIDLTAVVINNSLYGMTGGQLAPTTPEGAKTKTSPYGNVERPFDIAKLAIAAGASYVARFTAYQPRWIEKAIFEAMQHHGFSVVEVVTGCPTHQRIKPADLLKHLKENFRRRDNVSLDEIQPTDIGVFKKEVMEEFCEKIEKLRMYVRKGENKENV
What are the official names of this protein?
2-oxoglutarate synthase subunit KorB, 2-ketoglutarate oxidoreductase beta chain, KOR, 2-oxoglutarate-ferredoxin oxidoreductase subunit beta.
Protein: MIAA_KOSOT
Sequence: MKIPMILGATAVGKTQFLVKLASLIPIEVVSVDSRQIYRYMDIGTAKPTREELSKLKHHVIDVVDPDEDFNVFEYRKIALKAMDEIVKKGRIPVFAGGSGLYAETLMKGIVENVPRNDKVREALKTLEVNAPGSLRKLLEKVDHEAYEKIHPNDLKRTIRYLEVFFTTGKTLTSLQKIHKCSNQFTVIILERDRRELAERIENRVDKMVESGLIEEVVRLKEMGYTRELNSQQTIGYAEIWSYLEGEVTLERATELIKRNTRRFARRQIIWFRRYKDAKRISLSETNENDILSLLKEDILNVWGGKYG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CCL10_HUMLU
Sequence: MEKCFNPETQIYSSHRPPVNFPTDPKLSLTSFLFRSSASYPNRTALIDADSGQTLTFLKLKTQVSKLAHSLVQLNIKKNDVVLIFAPNSIHFPVCFFSIAALGAITTTCNPSYTFTELSNQAKDCNPTLVITVPELWEKARKLNLPAIILPSPSNSKLSSKSEFWFFSDLTRKSDRFSELPISDVRQSDVAALLYSSGTTGKSKGVVLSHKNFITTSLMVTSDQDRYGDPQNICMCFLPMFHIFGLSVIAYSQLRRGNGVVSMGKFELEGALRAVEMYRVTHLFVVPPVMIALAKESVVVRRYDLSSVKEILSGAAPLGKNVMEQCARNVPGAAIIQGYGMTETCGIISIEDSKKGCRFSGSTGMLAPGIESQIMDTKRWNPLPPNQEGEIWLRGPNMMQGYLNNLEATKSTIDEQGWVKTGDIGYFDEEGQLFVVDRLKELIKCYGFQVAPAELEALLLSHPEILDAVVIPFPDEKAGEVPIANVVRSPNSSLSEEDVQRFIEKQVAPFKKLRRVTFVSSVLKSPAGKILRRELIQKVRSKI
What are the official names of this protein?
Probable CoA ligase CCL10, HlCCL10.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: UXAC_THESQ
Sequence: MFLGEDYLLTNRAAVRLFNEVKDLPIVDPHNHLDAKDIVENKPWSDIWEVEGATDHYVWELMRRCGISEEYITGSRSNKEKWLALAKVFPRFVGNPTYEWIHLDLWRRFNIKKVISEETAEEIWEETKKKLPEMTPQKLLRDMKVEILCTTDDPVSTLEHHRKAKEVVEGVTILPTWRPDRAMNVDKEGWKEYVEKMGERYGEDTSTLEGFLSALWKSHEHFKEHGCVASDHALLEPSVYYVDENRARAVHEKAFSGEKLTQDEINDYKAFMMIQFGKMNQETNWVTQLHIGALRDYRDSLFKTLGPDSGGDISTNFLRIAEGLRYFLNEFDGKLKIVLYVLDPTHLPTIATIARAFPNVYVGAPWWFNDSPFGMEMHLKYLASVDLLYNLAGMVTDSRKLLSFGSRTEMFRRVLSNVVGEMVEKGQIPIKEARELVKHVSYDGPKSLFFR
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RL11_CORU7
Sequence: MAKKKKVQALIKLQIQAGAATPAPPVGPALGAHGVNIVEFTKAYNAATESQRGNIVPVEITVYEDRSFDFKLKTPPASKLLLKAAGLQKGSGVPHTDKVGKVTWDQCKEIAKTKEPDLNANDIEAGAAIIAGTARSMGIDVEGRPSA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CXAT1_CONPO
Sequence: MPKLAVVLLVLLILPLSYFDAGGQAVQGDWRGNRLARDLQRGGRDDESECIINTRDSPWGRCCRTRMCGSMCCPRNGCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Vt20.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSP1_ROTH7
Sequence: MATFKDACYHYKKLNKLNNLVLKLGANDEWRPAPVTKYKGWCLDCCQYTNLTYCRGCALYHVCQWCSQYNRCFLDEEPHLLRMRTFKDAVTKEDIEGLLTMYETLFPINEKLVNKFINSVKQRKCRNEYLLEWYNHLLMPITLQALTINLEDNVYHIFGYYDCMEHENQTPFQFINLLEKYDKLLLDDRNFNRMSHLPVILQQEYALRYFSKSRFLSKGKKRLSRNDFSDNLMEDRHSPTSLMQVVRNCISIHINDCEWNKACTLIFDARNYISIMNSSYTEHYSVSQRCKLFTKYKFGIVSRLVKPNYIFSSHESCALNVHNCKWCQINNHYKVWEDFRLRKIYNNIMDFIRALVKSNGNVGHCSSQESVYEYISDLFLICKTGKWNEAVEMLFNYLEPVDINGTEYVLLDYEVNWEVRGLVMQNMDGKVPRILNMNDTKKILSAMIFDWFDTRYMRETPMTTSTTNQLRTLNKRNELIDEYDLELSDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.