PharMolix/UniProtQA huggingface dataset:
Protein: GB_HHV7J
Sequence: MKILFLSVFITFSLQLSLQTEADFVMTGHNQHLPFRICSIATGTDLVRFDREVSCASYGSNIKTTEGILIIYKTKIEAHTFSVRTFKKELTFQTTYRDVGTVYFLDRTVTTLPMPIEEVHMVNTEARCLSSISVKRSEEEEYVAYHKDEYVNKTLDLIPLNFKSDTVRRYITTKEPFLRNGPLWFYSTSTSINCIVTDCIAKTKYPFDFFALSTGETVEGSPFYNGINSKTFNEPTEKILFRNNYTMLKTFDDGSKGNFVTLTKMAFLEKGNTIFSWEVQNEESSICLLKHWMTIPHALRAENANSFHFIAQELTASFVTGKSNYTLSDSKYNCINSNYTSILDEIYQTQYNNSHDKNGSYEIFKTEGDLILIWQPLIQRKLTVLENFSNASRKRRKRELETNKDIVYVQLQYLYDTLKDYINTALGKLAEAWCLNQKRTITVLHELSKISPSGIISAVYGKPMSAKLIGDVLAVSKCIEVNQTSVQLHKSMRLTKDSSYDALRCYSRPLLTYSFANSSKETYLGQLGLDNEILLGNHRTEECEQSNTKIFLSGKFAHIFKDYTYVNSSLITEIEALDAFVDLNIDPLENADFTLLELYTKDELSKANVFDLETILREYNSYKSALHHIETKIATVTPTYIGGIDTFFKGLGALGLGLGAVLGVTAGALGDVVNGVFSFLKNPFGGALTILLTLGVIGLVIFLFLRHKRLAQTPIDILFPYTSKSTNSVLQATQSVQAQVKEPLDSSPPYLKTNKDTEPQGDDITHTNEYSQVEALKMLKAIKLLDESYKKAEIAEAKKSQRPSLLERIQYRGYQKLSTEEL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: KRFA_CHICK
Sequence: MSCYDLCRPSAPTPLANSCNEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSEEGVPISSGGFGISGLGSRFSSRRCLPY
What are the official names of this protein?
Feather keratin 4, F-ker, Keratin gene A protein.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: GRK1_CAEBR
Sequence: MEIENIVANTVYIKARESGGQKKGKSKKWKNYLQFPHYTECIPQKKENGEPYAFVVEKQPIGKLLFHEFCQATNPQYHQCCQFQTKVEEYETSDDDGQSRRDLASAIVALLSSKNDQDLSSSIDEEVWCAFLSDEVISTCISTADSATHDSEPRSDIFSEPYRLTREYLKQKPFAEFIQTMYFHRFLQWKWLEKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQKVNSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAEITLGLQHLHLEHILYRDLKPENILLDDFGHVRISDLGLAVELKDNEPIKGRVGTVGYMAPEIVKNERYTYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGKPEDGAEEIRAHPFFNTADTATGREPVPWKKMEAGKVTPPFCPDPRAVYAKDVLDIEQFSTVKGVRLDATDTQFYGKFNTGCVSIPWQSEMIETECFAELNTFYEEDGSLVWNLRPDGINMEERRNGTSKPGFFSRLFRKKNIEVTKSLHDLSRLGVDQQQPSTSAKPAAVRSSRAASASGRTSMI
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors.
What are the official names of this protein?
G protein-coupled receptor kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Protein: AQP5_SHEEP
Sequence: MKKEVCSAAFLKAVFAEFLATLIFVFFGLGSALKWPSAMPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYLVAQLVGAIAGAAILYGLAPYNARSNLAVNALNNNTTAGQAVVAEMILTFQLALCVFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVIMSRFSSAHWVFWVGPIVGAATAAIIYFYLLFPHSLSLSDRVAILKGTYEPDEDWEESQEERKKTMELTAH
What is the function of this protein?
Forms a water-specific channel (By similarity).  Plays an important role in fluid secretion in salivary glands.  Required for TRPV4 activation by hypotonicity.  Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells.  Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
What are the official names of this protein?
Aquaporin-5, AQP-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Protein: Y1105_METKA
Sequence: MILTLDPQVAGASGDMVLGALIAVGADPNRLEEVVHEVSSLGHEVDVHVHEIQKRGIRAVRVEVDAEGDLRDPDELREAVKTVAENVLEDRWRELPELALKYLLRAEERVHGDLCHLHELGSSDTVVDLVGTAALLEDLNPKASEVLPPNVGSGTVETEHGRLPVPAPAVVEVLSEWDVGIVREGEGELLTPTGAALLRTIDELLPDPPPPYRVKRQGFGAGTKDLPDRPNVLRALICEPGGSGEHVRIVETSVDDVDGEAVGELIEAVLQLEGVHDVEVLHGFGKKGRPRFVIRVVTEDRPGIEREVFRELFRWTGTLGARVYRCTRVTADRRIVDVDGIRVKVSRFEDVHHAKPEWEDVRRKVDRESAPLTRARLVGDLRKRYEGDGEDGAGD
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: RPIA_PSEFS
Sequence: MTQDQLKQAVAQAAVDLILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEATAARLKGHGIPVYELNTVSDLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVAKTFICIADASKLVPVLGAFPLPVEVIPMARSHVARELVKLGGDPVYREGVLTDNGNIIIDVFNLQITNPVELETQINAIVGVVTNGLFAARPADVLLLGTSEGVKTLKA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GPDA_BACC1
Sequence: MTKITVVGAGSWGTALAMVLADNGHDVRIWGNRSELMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNVVLLVVPTKAYREVLQDMKKYVAGPTTWIHASKGIEPGTSKRISEVIEEEIPEDLIKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNLLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WASC2_DICDI
Sequence: MPEEQPQQQQQPVREQPSNPDDVPWKKVWTINEMRDSAKDWNLSSDAGLLNYMQDFANKLIYKTKELEFQVDELVKDSKSIHVKVHNTFDQFLMLSNTQFIENRVYEDNSELNNEQNEQTDKPQQQEITEEILIPKFSKAILIGLEALEKANFVNAALEISEQSNSNNNNNDYQQQMNGSIAASSAEGGLVEGGEQAGTDAQPSANTEKKKEKLDHYLRYPLPHIIGSQQFHQDDFCGLFIEDSDSDSSDEEDEEDVDAEDGSDESSSESSSDDDDEKDEQQQSTLFLTDEQPKQQNFFFQDEDATSENNANKKVSESLFEDEDDIFGDKPVASKKSSNSYTSSLSDILGGDDEDDLFGGSKKKQQQQEDADGDEPTKKKDPFADELNNTLSSKNKGGDDDLFGGSSSTTTTSKPKKKSMFDDDLFGDSEETPAPKSSASRKVTFDDSLFGDDETALPTSKKDSTTTSSQPQQKKTLNDLFTDEDLTPATKKETKKSSSLSFLDGMDEDDLFGTPKPKSTTTSAAPTATTTKPPTPIPDSDASGSESTTGKSSPAPKKPVGGVKLFDFDAAGGDIFSGKKVGTGGKSSPSPAPKTESKASEDDFFSSDKKSTSATKKDAEIFGSEGGLLDVPEKKIKRHDPKKYVDSDVLGIDSISSDKNKPKVQDPFGVGAAGSNDDDSFDIPKANSKKEQETKPTKSTTTDDDLDIPKAPTTATTTTTTKPAVKKSTKSNFFDFEDTDSPLSSNKKSGGDDDLFSFDSSKTTTETKKQPITEEPKKKQDTTTTPSIDPFSGLDIKKPSEASISPASPVSTIESDPLFGDIKKPVAQKPKKTNFFDGDLTKDEPAKSEPTKVEPTKVEPTKAEPTKVEPAKVEPTKVESDKKESNPLGGGDEESVFGDFSIKKNPTTSSSTTATENKPAVKKSTKSNFFDFEDTDSPLSSNKKNDDDIFSSTTKKSTTTTTTTTSSKDFFGDLDTSSGNKKVEEKKSSDFDSFFSGSDDPLGITKPKSKTTTTPPLTSTTANIESDDPLSLGLPTFTNNNNNNNAKPPPPPSPLGEDVPSPLTSNNTKNRTKSIGSMFEAQQQLQQQQQEKNRSESPTSEKAEPTKKTSNISSLQNKLSLNPNMFLPGSKMPKKKKEESENEDDSSTNNDNDSSATDLSDSGRSSPSVTSPTLSGGRPRRNTVSSRNNNDSEESEPVKELTHATASRPKSGGRRPPTRKSGTSAPNRSESPTPTQKSDSESEKVRSSSPITTKPVVSEPTKKTISNTSFFDDIPSEKTSSGKSSPSPTIKSTSEKVTIDPLGDIFASTTTKPTASETKAALSSAPKKSEPETPKETPKETPKEKEQTKEKEQPKETPKTTTTKKSTKAVETKSETDSFFDDIPDIISRPKASVKSAAAKKASSTTKPVISDDIFDDITSTTSKSTTTTTTTTTTKAKSTKAVDNLFDDDTNTTTKATPTKATPSKSKPKAKNVENLFD
What are the official names of this protein?
WASH complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the FAM21 family.
Protein: LTBP4_HUMAN
Sequence: MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA
What is the function of this protein?
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space.  Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
What are the official names of this protein?
Latent-transforming growth factor beta-binding protein 4, LTBP-4.
What is the protein family that this protein belongs to?
Belongs to the LTBP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DRS3_PHYDS
Sequence: ALWKTMLKKLGTMALHAGKAAFGAAADTISQ
What is the function of this protein?
Antibacterial activity against Gram-positive bacteria S. aureus and E. faecalis, and Gram-negative bacteria P. aeruginosa and E. coli.
What are the official names of this protein?
Dermaseptin-DI3, DRS-DI3, Dermadistinctin-M, DD M.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNP4_METVS
Sequence: MKLKKKFLEKSKNIANERIDILMNFAQKELRCEKKERSKNYVLLSKKIAMRMRMPFPKEWRRRICKNCGSFLIYGKNSSVRIKSKNYSHVVITCLECKHIFRIPIKKSK
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBP_CHLRE
Sequence: MATALCNKAFAAAPVARPASRRSAVVVRASGSDVSRRAALAGFAGAAALVSSSPANAAYGDSANVFGKVTNKSGFVPYAGDGFALLLPAKWNPSKENDFPGVILRYEDNFDAVNNLVVIAQDTDKKAIADFGSQDKFLESVSYLLGKQAYSGETQSEGGFAPNRVSAASLLDVSTTTDKKGKTYYKYELLVRSADGDEGGRHQLIGATVGSDNKLYIIKIQIGDKRWFKGAKKEAMGAFDSFTVV
What is the function of this protein?
May be involved in the regulation of photosystem II.  Required for high levels of photosynthesis oxygen evolution.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: K1H1_HUMAN
Sequence: MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR
What are the official names of this protein?
Keratin, type I cuticular Ha1, Hair keratin, type I Ha1, Keratin-31, K31.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: CH602_CORJK
Sequence: MSKLIAFDQEAREGLQKGVDALADAVKVTLGPRGRNVVLDKAFGGPTVTNDGVTIARDIDLEDPFENLGAQLVKSVAIKTNDIAGDGTTTATLLAQALVNEGLRTVAAGANPIAVNRGIAKGTERVVELLRELAQPVADNAAIANVATVSSRDEKIGAMVADAFDKVGKDGVVTVEESQSIEDESIVTEGVSFDKGYLSPYFVTDQETGHAELENPLILLVREKISSLPDFLPVLEKVANSGKPLLIVAEDIEGEPLQMLVLNAIRKSLKVAAVKSPYFGDRRSAFMDDLAIVTGGTVIDSELGHKLSETTLEQLGSARRVNITKEETVLVDGAGSAEAVEERRNQIRNDIERTDSSWDKEKFEERLAKLSGGVAVIRAGGATETEVNERKLRIEDAINAARAAGQEGVIAGGGSVLVQIADEIEELSRKEEGDEGIGLRSLARALRRPAYWIADNAGLDGAVVVSKIAEQPNGSGFNAATLEYGNLLEQGIIDPVKVTHSAVVNATSVARMVLTTETAVVDKPAAPAGQAGAHAGHAHAH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRB_STAAT
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVVFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKMAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: MUTS2_BACC3
Sequence: MLERTLRVLEYNKVKEQLLEHTASSLGRDKVKHLVPSTDFEEIVEMQDTTDEAAKVIRLKGSAPLGGITDIRSNVKRAKIGSMLSPNELLDIANTMYGSRNMKRFIEDMVDNGVELPILETHVAQIVSLYDLEKKITNCIGDGGEVVDSASDKLRGIRTQIRTAESRIREKLENMTRSSNAQKMLSDSIVTIRNERYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEIERILLMLTEEVAVEADIVLSNVEVVANLDFIFAKAFYAKRIKATKPIVNNERYMDLRQARHPLIDPEIIVPNNIMLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVMDESEICVFKNIFADIGDEQSIEQSLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVCNRGARVVATTHYPELKAYGYNREQVINASVEFDVNTLSPTYKLLIGVPGRSNAFEISKRLGLSDRVIDQARNHISTDTNKIENMIAKLEESQKNAERDWNEAEALRKQSEKLHRELQRQIIEFNEERDERLLKAQKEGEEKVEAAKKEAEGIIQELRQLRKAQLANVKDHELIEAKSRLEGAAPELVKKQKVNVKNTAPKQQLRAGDEVKVLTFGQKGQLLEKVSDTEWSVQIGILKMKVKESNMEYINTPKQTEKKAVATVKGRDYHVSLELDLRGERFENAMARVEKYLDDAQLASYPRVSIIHGKGTGALRQGVQDYLKKHRGVKTFRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: HGH1_DROME
Sequence: METVKELVQFMQPNQRLDLKAVALTHVLGLTGSSEGKSAILSLDEMLMAIFGLTFDANQTVAKDAVLSLINLTSEEEAAIKVFQLAKQLQPPFAIVEVAAKEITNEQSDLADPWSMVLSNLTRVESLVHEILDTLERDDHTLPRLAKAFAQLDYNKKKAKLHYLAPIFCNLTQVSRGRELCCHRKYELLEKLLPFASFEGSVVRRGGTIGILKNVCFDTVYHDVILNEQSSILVAILQPLCGPEEFSDEDNELLPIELQYLPESKTREEDPDLRKMLLECLLQLCSTRRSREILRSRGVYEILREYHKWEAKVGKDSDCLLACENVVDILIKKEEEIGLDNYKTEVEVPAEQSEKFVQEDAAYVKSLLD
What are the official names of this protein?
Protein HGH1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HGH1 family.
Protein: GP12_BPLP2
Sequence: MAKQLSTARKFKMITGKDLFQQQKAMDTELKKEDGEITDLMEFVQYGLYLALFQDNIVKAKSDFSDFRSSFEFDTDGKGLKELVELWQKEI
What is the function of this protein?
Probable chaperone for the tape measure protein.  Might help to maintain the tape measure protein in solution during tail assembly.
What are the official names of this protein?
Chaperone protein gp12, Gene product 12, gp12.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus chaperone protein gp12 family.
Protein: RFCS_METM6
Sequence: MQKPWVEKYRPETLPEVVGHHEIIKRLTNYVEKKSMPHLLFSGSPGVGKTTAALALAKDLYGDTWRENFLELNSSDERGIDVIRTKVKDFARTKPIGDAPFKVIFLDESDALTSDAQNALRRTMEKYSDICRFILSCNYPSKIIPPIQSRCAIFRFSPLKTEDLVENLKDISEKETLTLEKGGIDAIIYVSEGDMRKAINVLQTAAAVSDTVTEEIVYKVASKARPDEIKKMTQLALNGKFVEAREQLYNLMIDWGMSGEDILIQVFREVPNLDISEKEKVHLVEAIGECDFRIVEGSNERIQLSALLAKMGILE
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: VTC4_TRYB2
Sequence: MPFSKAWRSAVYPDFREQGAYINYKATKDTLHRMKEDIANPATPDELYNSLLMQKATVYKWCENKVKELQMMAEALMKASDYLSEEETPTNMSMVFSMVGSSEAKYLPPSDARRVADAITYELLRFVECRNLNTDTIEHIIARMYRYAVLGPTGDRWKNINKEYDYHALSIDEIFFMLSKVYEHVNEVESMRRDGRSSIPCGTVGSQVFDRRSVKYWVHMQDLPFVIARIIPHLPLSTFQDTYAMSKERGVPFTLGSPISSVYYDNDKFLLYHRRLERLDGATLIRMRWYGRPLDSDWNKLESKDSVFMEIKVHHEAWSGERSNKRRFALKEKDVDAYIRGDLSLKPALEKLRSKNASEAEQEKFMSLATEILTKIHAYDLKPVLRTQCQRAAFQCGLDQSIRISIDTDLRVVAEDFGLSHHWRYNGADAPLSHFPYAVVEVKLQCAENERIAPWIEELMNCRYMESVPKFSKYAHGIATLYGHTPFIKMVPYWMPQLDIDIRASTKPEYNQWDPTIGIASGCWERTTDRVIFGTGHAQTQTVGASEARFLPRTDCLRTYQRVLKAIKRGAHMNSVAPTMSPTDRPPSDEKKLTEQQELAPVVQYDTDRRHKAYTAFHLYPYCEDGVESLCFTSTGGKHVAAEVFSGLIPWQTGKRIRVPQKYDPKTLLTSERFMVKWAEQATRVGVVGLAVIRFGNSMSLPNDMVAVHSFWRANFHIVLGSLMVVVAECVLVYAYVTFKSRSRRVYARRKIRYDDRRGPVALTFVILAVILITVMMHVMVRYGPMLTGSDTF
What is the function of this protein?
Component of a polyphosphate synthase complex that utilizes ATP to synthesize and translocate polyphosphate to acidocalcisomes in epimastigotes, insect-stages of Trypanosoma brucei (PubMed:24386955).  Catalytic subunit of the vacuolar transporter chaperone (VTC) complex.  The VTC complex acts as vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP.  VTC exposes its catalytic domain vtc4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation.  The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen.  PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase.  The VTC complex also plays a role in vacuolar membrane fusion (By similarity).  Essential for infection and parasite survival in the mammalian host (PubMed:24114837).
What are the official names of this protein?
Vacuolar transporter chaperone complex subunit 4, Polyphosphate kinase, SPX-dependent polyphosphate polymerase VTC subunit 4, Vacuolar membrane polyphosphate polymerase catalytic subunit, PolyP polymerase.
What is the protein family that this protein belongs to?
Belongs to the VTC4 family.
Protein: RL34_METTH
Sequence: MPELRYRSRSYKRIFKKTPGGRTVTHYRRKKPSKHVCAGCGKPLHGVPRGRPYEIRKLSKSKKRPNRPYGGYYCSSCARKVFKKEARS
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: EIF1B_HUMAN
Sequence: MSTIQNLQSFDPFADATKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLLEVGIVKEEQLKVHGF
What is the function of this protein?
Probably involved in translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 1b, eIF1b, Protein translation factor SUI1 homolog GC20.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: HFM1_XENTR
Sequence: MTLPFSWITNDVSQCIDLTQDEHICSLSPVTDTEENMSAFKKSLFGKYDCSLNSEDQCLIVENGSSNFVTSKEAQKEAMKADSDICPPQQMAFNLFNETVVQKDMLNKEKFSHSASSNISNKDDAQYGIVTPVTEIPKQFRTVFKEFPYFNYIQSKALEHLLYSDRNFVLCAPTGSGKTVIFELAIIRLLMQVPMPWTNVKIVYMAPIKALCGQRYDDWKAKFGPVGLNCKELTGDTEMDDLFEIQHAHIIMTTPEKWDSMTRKWKDNTLVQLVRLFLIDEVHILKEENRGATLEVVVSRMKTIYSLSHLSEDRKAFIPMRFVAVSATIPNVEDIADWLSDENSPGVCMKMDESSRPVKLRKVVLGFPCSTKQSEFKFDLTLNYKIANIIQTYSDGRPTLVFCSTRKGVQQAASILTKDAKFVMSIEHKQRLQKCANSIKDSKLRDVLQYGVGYHHAGVDISDRKVIENSFLIGDLPVLFTTSTLAMGVNLPAHLVIVKSTMHYVSGMFQEYSETDILQMIGRAGRPQFDSTATAVIMTRLSTKEKYVHMLDGADTIESSLHKHLVEHLNAEIALHTITDVKVALEWIRSTFLYIRALKNPAYYGFSEGLDKIGIEAKLQELCLKNLNDLSSLGLIKMDEEINFKPTETGKLMALYYIAFNTAKLFHTIRGTETLAELVSLISSCSEFSDVQLRANERRVLNTLNKDKNRVTIRYPMEGKIKTKEMKVNCLIQAHLGCILVQDFSLTQDISKIFRHGTRLAKCLSEFLALQENKFSAFLNALILTKCFKSKLWENSSHISKQLEKIGVTLANAMVNAGLTTFKKIEDTNARELELIVNRHPPFGNQIKESVAHLPKYEIKFQQLAKYRATTAEVVLTVLLTNFKQLQKKRTAPDSHFVMLVIGDDDNQAIFKQKIMDSSLFKTGSWTRKIEIKRASKSTNVCLNLISSEYVGLDIQQSFNICYLGSDSFNADLVTQHKSENIFSQEIYKTSTKTKDIADTNWSMRQTAIKCATRECNHNCKNKDACGHECCKVGVSEKAEMKTNFYSYLNDLRTRNSVSSATPVKRLKMQMEAETRNVNLQNFVFTPKPSIRSPCLKIPENILLQAESSVLTNKYKASHQEETCCKYEIKGCGEKQTKGMPKKTCERRNLTDSDKCNSSSSENAAYVTFDLGNDIWDDFDDDNLLDASNISSLTDQHTSEFTDVSFSKNQPVSKSSLSAGHHEEARYNAMSINKDSYRYLNAKSEVFSQENTQCIDVVPSNQKLHGKMFSENTIKHMFTLQEETNYPVTSKMDSPHNGCWSSNIFFKTPENKTQERGCYHQEDETNAFIGIFNGIF
What is the function of this protein?
Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
What are the official names of this protein?
Probable ATP-dependent DNA helicase HFM1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
Protein: VES_SHIB3
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPLQPFAFAADQVVKAKLTEGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: MKNK1_RAT
Sequence: MGSSEPLPIVDSDKRRKKKRKTRATDSLPGKFEDVYQLTSELLGEGAYAKVQGAVSLQSGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNELEASRVVRDVATALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAHISTEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEHEALAEGLCSMKLSPPSKSRLARRRALAHAGREANSCSTPAGL
What is the function of this protein?
May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.