PharMolix/UniProtQA huggingface dataset:
Protein: FLHD_ECOL6
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_RHDSA
Sequence: MPRFQKNDNFIDKTFTVLADIVLKVLPASKQEKEAFSYYRDGMSAQSEGEYAEALENYYEALRLEEDPYDRSYILYNIGLIYASNGEYIKALEYYHQALDLNSRLPPALNNIAVIYHYQGVKASEKKDLETARTMFDKAAEYWKQAIRLAPNNYIEAQNWLKTTGRMASESLY
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FTHS_CALS4
Sequence: MKSDIEIAQEAKMLHIRDVAAKLGIEEDYLEYYGKYKAKISPALWDKIKDRKDGKLILVTAITPTPAGEGKTTTTVGLGQALAKLGKKAMIALREPSLGPSFGIKGGAAGGGYSQVVPMEDINLHFTGDIHAITAAHNLLAAMIDNHIHHGNELNIDIRTITWKRAMDMNDRALREIIVGLGGKANGYPRQDGFIITVASEIMAILCLSHDLMDLKRRLGDIIVAYDKDGSPVTARDLKADGAMAVLLKDAIKPNLVQTIENVPAFVHGGPFANIAHGCNSLIATKYGLKLADYLVTEAGFGADLGAEKFFDVKARFGGLTPNAAVVVATVRALKMHGGVKKEDLQKEDVEAVRRGIENLEKQVENVRKFGVPVVVALNKFVFDTEREIEEVRKACDRIGVDMAVAEVWEKGGEGGIELAEKVIKAADTPSNFRFLYDVNLPIKDKLHIIATEIYGADGVEYTASALKDIANIEKLGLDKMPIVVAKTQYSLSDDPKLLGRPRGFKITVRELRISRGAGFIVALTGDIMTMPGLPKHPAAENIDIDENGRIKGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: HIS4_PSYCK
Sequence: MCAVPVIIPAIDLKDGKCVRLKQGRMEDDTVFSDDPVAMAARWVKEGARRLHLVDLNGAFDGIPVHKQVVHDIAKAFPKLPIQLGGGVRNMQTIEQYITAGLTYIIIGTKAVEDPDFVAEACREFAGHIIVGIDAKDGMVATHGWANVTDTKATELAKRFADVGVSSIVYTDIARDGMMQGVNVEQTVNLAREGGLPVIASGGVTDMKDIELLKPYGDCIEGIITGRAIYEGTLDLGEAQLYLDGK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX4_DICDI
Sequence: MFALRSIRSATKAFQTTSIVSQRGFLQTTLKNVLFPTERQLRRQYLADNHIKVGSPEFDKFYEDLQPSELSKQSGLSDALLDDPILHICVIKYNKNIVQRYNLTPEQEKDIMENYNVSAGDPSLEQILPIPVPAHIFEELPIVKVLNN
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
What are the official names of this protein?
Cytochrome c oxidase subunit 4, mitochondrial, Cytochrome c oxidase polypeptide IV.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: NUSB_RHOPS
Sequence: MVEPKKPFMRKPPPKTGDKKPGDRKANRRGAARLAAVQALYQMDIGGAGIDDTFAEFESHWIGNEVEGDQYLPAEAAFFRDIVSGVVRDQTKLDPLIDEALAKGWPLARIDAIIRAVMRAGAYELEHRKDIPARVVVSEYVDVAHAFVEKDETGMVNAVLDQIARQFRADEFTK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: GATC_BACSU
Sequence: MSRISIEEVKHVAHLARLAITEEEAKMFTEQLDSIISFAEELNEVNTDNVEPTTHVLKMKNVMREDEAGKGLPVEDVMKNAPDHKDGYIRVPSILD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MURJ_BURCJ
Sequence: MNLFRALLTVSGFTLLSRVTGLARETLIARAFGASQYTDAFYVAFRIPNLLRRLSAEGAFSQAFVPILAEFKNQQGHDATKALVDAMSTVLAWALAVLSVVGIAGASWVVFAVASGLHSDGQAFPLAVTMTRIMFPYIVFISLTTLASGVLNTYKSFSLPAFAPVLLNVAFIAAAVFVAPHLKVPVYALAWAVIVGGVLQFLVQLPGLKKVDMVPLIGLNPLRALRHPGVKRVLAKMVPATFAVSVAQLSLIINTNIASRLGQGAVSWINYADRLMEFPTALLGVALGTILLPSLSKAHVDADSHEYSALLDWGLRVTFLLAAPSALALFFFATPLTATLFNYGKFDAHTVTMVARALATYGIGLVGIILIKILAPGFYAKQDIKTPVKIAIGVLIVTQLSNYVFVPLIGHAGLTLSIGVGACLNSLLLFLGLRKRGIYQPSPGWLRFFVQLVGAALVLAGLMHWCAINFDWTGMRAQPLDRIALMAACLVLFAALYFGMLWVMGFKYAYFRRRAK
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WBP1L_HUMAN
Sequence: MPFLLGLRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPTRGSQGAQSSPLSEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREELLKDDSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSPS
What are the official names of this protein?
WW domain binding protein 1-like, Outcome predictor in acute leukemia 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SODF_PLAF7
Sequence: MVITLPKLKYALNALSPHISEETLNFHYNKHHAGYVNKLNTLIKDTPFAEKSLLDIVKESSGAIFNNAAQIWNHTFYWDSMGPDCGGEPHGEIKEKIQEDFGSFNNFKEQFSNILCGHFGSGWGWLALNNNNKLVILQTHDAGNPIKDNTGIPILTCDIWEHAYYIDYRNDRASYVKAWWNLVNWNFANENLKKAMQK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe], FeSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_STACT
Sequence: MLKKNKDELNDLEYLVTQENGTEPPFQNEYWNHFEKGIYVDKLSGKPLFTSEEKFESDCGWPSFSKALSDDEVVELVDKSFGMVRTEVRSEDSNSHLGHVFNDGPAETGGLRYCINSAAVQFIPYDKLEELGYGDLIPHFKDQGEK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: PGK_MYCBO
Sequence: MSVANLKDLLAEGVSGRGVLVRSDLNVPLDEDGTITDAGRIIASAPTLKALLDADAKVVVAAHLGRPKDGPDPTLSLAPVAVALGEQLGRHVQLAGDVVGADALARAEGLTGGDILLLENIRFDKRETSKNDDDRRALAKQLVELVGTGGVFVSDGFGVVHRKQASVYDIATLLPHYAGTLVADEMRVLEQLTSSTQRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGTSLLEDDMIEVCRGLLETYHDVLRLPVDLVVTEKFAADSPPQTVDVGAVPNGLMGLDIGPGSIKRFSTLLSNAGTIFWNGPMGVFEFPAYAAGTRGVAEAIVAATGKGAFSVVGGGDSAAAVRAMNIPEGAFSHISTGGGASLEYLEGKTLPGIEVLSREQPTGGVL
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTD_RAT
Sequence: MSGARTAHALVFLLGCSALALGVCSASLEHGEAEYYVAAVYEHRSVLSPNPLELSSRQQALELMKQNLDVYEQQVMAAAQKGAHIIVFPEDGIHGFNFTRTSIYPFLDLMPSPRLVSWNPCLEPFRFNDTEVLQRLSCMAIKGKMFLVANLGTKQPCLGSDPGCPQDGRYQFNTNVAFSDNGTLVGRYRKHNLYFEEAFDSPADVDLTTFDTPFAGKFGMFTCFDILFFDPAVRLLRDFEVKHIAYPTAWMNQLPLLAAIEIQKAFATAFGVTVLAANIHHPTLGMTGSGIHTPLKSFWYHNMDDPEGHLIIARVATNPQGLVGTENTTSEMDPSHRKFLKVLSGDPYCEKDAQEVRCDEAAKWNLNAPPTFHSEMMYDNFTLVPVWGKEGHLQVCSNSLCCHLLFERPALSKELYALGVFDGLHTVHGTYYVQACALVKCGGAGFETCGQEISEAEGLFDFHLWGNFSTLYVFPLFLTSGMTLDTPDQLGWESDHYFLRKRGLSSGLVTAALYGRLYERN
What is the function of this protein?
Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
What are the official names of this protein?
Biotinidase, Biotinase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DRTB_ASPCI
Sequence: MVRALILDLGDVLFNWDAPASTPISRKTLGQMLHSEIWGEYERGHLTEDEAYNALAKRYSCEAKDVAHTFVLARESLRLDTKFKTFLQTLKQNANGSLRVYGMSNISKPDFEVLLGKADDWTLFDKIFPSGHVGMRKPDLAFFRYVLKDISTPVEDVVFVDDNLDNVTSARSLGMRSVLFHKKDEVQRQLTNIFGSPAERGLEYLSANKTNLQSATTTDIPIQDNFGQLLILEATEDPSLVRMEPGKRTWNFFIGSPSLTTDTFPDDLDTTSLALSIVPTSPDVVNSVIDEIISRRDKDGIVPTYFDNTRPRVDPIVCVNVLSMFAKYGREHDLPATVAWVRDVLYHRAYLGGTRYYGSAEAFLFFFTRFVRNLRPGTLKQDLHALLSERVRERLNTPVDALALSMRIQACHALGFDAPADIATLITMQDEDGGWPAAVIYKYGAGGLGITNRGVSTAFAVKAITGSPVKTETNIGGDGARAVSAMSSLEARRLQPISSVGDWVRFIIASLHVHLAWLWNVLLLSKVV
What is the function of this protein?
Drimenol cyclase; part of the gene cluster that mediates the biosynthesis of various drimane-type sesquiterpene esters, compounds that exhibit diverse biological activities and are widely present in eukaryotes (PubMed:34468074).  The pathway begins with the synthesis of the backbone drimenol by the terpene cyclase drtB using farnesyl pyrophosphate (FPP) as substrate (PubMed:34468074).  The cytochrome P450 monooxygenase drtD is then responsible for the hydroxylations at C-6, C-9 and C-12, as well as the oxidation of hydroxyl groups at C-6 and C-11 to a ketone and an aldehyde, respectively (PubMed:34468074).  Then, the biosynthesis can go in two directions, either the hydroxylated drimenol is further hydroxylated at C-2 and C-3 by an enzyme(s) not associated with the drt cluster, or the FAD-binding oxidoreductase drtC further oxidizes C-11 or C-12 to form the butyrolactone ring (PubMed:34468074).  DrtB, drtD and drtC are solely responsible for the formation of the different drimane structures observed during drimane sesquiterpenes biosynthesis (PubMed:34468074).  The polyketide synthase drtA synthesizes different lengths (C6 and C8) of PKS chains, which are then oxidized to varying degrees by the short-chain dehydrogenase drtF (PubMed:34468074).  Finally, these PKS chains are transferred onto drimane sesquiterpenes by the acyltransferase drtE, forming the sesquiterpene esters (PubMed:34468074).  In addition to the different fatty acyl-CoA chains produced by drtA, drtE is also able to use cinnamoyl-CoA as a substrate (PubMed:34468074).
What are the official names of this protein?
Drimenol cyclase drtB, Drimane-type sesquiterpene ester biosynthesis cluster protein B, Drimenol synthase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: RL25_GEOSW
Sequence: MAVVLEAKERPDKKHSTLRRIRLQGNIPGILYGKNIDNQMIFVSGAALEKTIREGGRHSLMTLKIGEKDYSVLLREIQRDPLRGNILHADFQAVDMSTEVDIDVDVRLIGEAAGEKDGGVLQQNLHQLTIRVLPANIPPSIDIDISHLQIGDTVTVGDINTGGKYEIIDDPSEVIATILPPQQEEEIHSGEQQEPGHPDAEEGRETTPES
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TYPH_SALA4
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDETSWQEAAKAVKAAIILDDKAPASTPSVYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RPOY_STRPQ
Sequence: MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVEDNTYYNVEFIELLSDKHLDYEKETGVFELTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: FBX25_HUMAN
Sequence: MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNRCNISHSIILNSEDGEIFNNEEHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity).
What are the official names of this protein?
F-box only protein 25.
What are the subcellular locations of this protein?
Nucleus. Note=In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
Protein: TIP_SHV24
Sequence: MENQREEIELTEIPETEKKRTAEEKLLSCSAETAEEKVSLCSEETTDTSSSSSSEQTPAPIEVNVNIQTSTYLPQNAATNLNSLYTSFEDARAQGKGLVRHNSDDLKSFLEKYPPDYRKPKRDLSESWDPGMPKPTLPPRPANLGASQASTVRRHVREQNFKQLRERKANEGKIVKDLKRLEYKVNIILCLVVVILAIILLLTGLSILFIRIKS
What is the function of this protein?
Plays a critical role in virus induced T-cell transformation.  Binds to T-cell-specific tyrosine kinase LCK SH2 and SH3 domains, thereby activating its kinase activity.  Once phosphorylated by host LCK, forms a complex with at least STAT 1 and 3, resulting on the phosphorylation of STAT3 and presumably STAT1, and their migration into the nucleus to induce transcription of target genes.  Stimulates host ILF3/NF-AT-90 activity.  Association with host NXF1/TAP transduces the signal up-regulating surface expression of adhesion molecules as well as activating NF-kappa-B activity.  Acts synergistically with StpC to stimulate NF-kappa-B activity and interleukin-2 gene expression.  Activation of NF-kappa-B protects lymphocytes from apoptosis, thereby facilitating viral induced cell transformation.  May cause down-regulation of host LCK and cell apoptosis when stably overexpressed ex vivo.  Interaction with WDR48 induce degradation of T-cell receptor in a lysosome-dependent fashion, when both proteins are overexpressed.  The biological effect of this interaction remains controversial since no T-cell receptor degradation is observed in infected cells.
What are the official names of this protein?
Tyrosine-protein kinase-interacting protein, Tip.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: PNG1_EMENI
Sequence: MADGKHHHSRRAPTTDAFDPAELTHAFEQLMRVKRFDRLLEKSRSPSRTQSPSPSPYRSQPSHPSQALPATQPAQPQPSSQSPSLRNLPIVPYPPQDQNAFKFRNLLHVLSVTPTKYENPGLLDEALSLIPLDKLYSEADEECQIIQAQARSLKRKPEWGYQDCVIRALLRWFKRSFFHWVNNPPCSRCLTPTIAHGRAPPTPDEAARGANRVELYRCADPSCGAYERFPRYSDVWQLLQTRRGRVGEWANCFSMFCRALGGRVRWVWNSEDYVWTEVYSEHQKRWIHVDACEETWDQPRLYAEGWGRKISYCIAFSIDGATDVTRRYVRSPAKHGAPRSRVPEEVLVWIIQEIRKMRRENRPKEEQRRLFKEDEREERELRMYTACALAAELKNLLPSNRSPSARPDEVKVPQTAEPQAAWNNSRQRSGHSGPDGSQGDR
What are the official names of this protein?
Protein PNG1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. PNGase family.
Protein: GUAA_STRPQ
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELHEINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEITKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GSHB_SCHPO
Sequence: MEIEKYTPEQIEELGKGARDFAFAHGVVFTELSVSKEGRNIATQIPITLFPSVIPHGAFVEAVSVQKAYNKLYAKIANDYEFLRLHLQSITKYDEFMNKLWNLYQKHREAVAHLKENQFQPLSLGVFRSDYMVHQDDSFIGCKQVEFNTISVSFGGVSKAVSNLHAYCSQSGLYRKPLTTNYLTVNTSVSGICTGISNAVDAYRDYVKNITSKMNIASDNTKPIVLFVVKGGERNITDQRTLEYELLNRFHVISKRIDIAELNSLIHDKSSNKLYMKTSFTTYEVAVVYYRVGYALDDYPSQEAWDMRLTIENTLAIKCPSISTHLAGSKKIQQVLAESNALERFLEGDELQAVRSTFADMYPLDDTPRGKEGIKLAFEKPEDFVLKPQREGGGNNTYGKDIPGLLSKMPQEEWDSYILMRYINAVPSQNYILKGERPEKFDVVDEIGILGTIVWNIKTDEVVQNGQSGFICRTKPKKTNEGGVATGYASLSSIELSE
What are the official names of this protein?
Glutathione synthetase large chain, GSH synthetase large chain, GSH-S, Glutathione synthase large chain, Phytochelatin synthetase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
Protein: ZCH18_RAT
Sequence: MDVAESPELEPHSPDEEQPALSDDDILRESGSEQDLDGAGERASDLEEEENATRVQSQEEIHSDEEDQASEPKSQDQDSEAHELSRGPAGSPCEEGDDAEEDGTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAAQEEEAEKAGAEEEEEKGEGAPGEEGKPDVQSVGEKEPTEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDREFDKENEVFRDWNSRVPRDVRDTTLEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRDRERERERENRQRERERDRERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDRDKDRDKDKEKPKPRSPQPPSRQAEPPKKETASVGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRRSSFSGSRSRSRSFSSSPSPSPTPSPHRPPVRTKGEPAPPPGKAGEKSIKKPAPPPAPPQATKTTAPAPEPAKPGDLREARRKERQTRTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSVHSVDSDDMYADLASPVSSASSRSPTPAQTKKERGKSKKEDGVREEKRKRDPSAQPPKSSKAPAGGKASQQAAAPQQAAPGQPQQGSFVAHKEIKLTLLNKAAEKGSRKRYEPSDKDRQSPPAKKANLSPDRGSRDRKSGGRMGSPKPERQRGQNAKAPAAPADRKRPLSPQSKSSSKVTSVPGKATDTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 18, Nuclear protein NHN1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_PSEF5
Sequence: MPQTLGFRELGQMAYEPVWQAMQRFTNERGTDAPDEVWLVQHPPVFTQGQAGKAEHLLLPGDIPVVQVDRGGQVTYHGPGQLVAYLLLDVRRLGFGVRDLVNRMEHCLIELLASYGVPAAAKPDAPGVYVNGAKIASLGLRIRHGCSFHGLALNVDMDLQPFRRINPCGYAGLAMTQLSDHAGPIEFAEVSARLRAQLVKHLDYAEQTTLTGGID
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR7AH_HUMAN
Sequence: MEPENDTGISEFVLLGLSEEPELQPFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFADICFISTTIPKMLINIQTQSRVITYAGCITQMCFFVLFGGLDSLLLAVMAYDRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQSLMVLWLSFCTDLEIPHFFCELNQVIHLACSDTFLNDMGMYFAAGLLAGGPLVGILCSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASVMYTVATPMLNPFIYSLRNKDIKRALKMSFRGKQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 7A17.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL4_NOCFA
Sequence: MSAVSTQKDTEKKANLVLPVKEAGGKSNGTVELPAEIFDVTANIALMHQVVTAQLAAARQGTHATKTRGEVSGGGKKPYRQKGTGRARQGSTRAPQFTGGGTVHGPQPRDYSQRTPKKMIRAALHGALSDRARNDRIHVVSELVAGQTPSTKTAKNFLAELSDRKKFLVVVGREDVTAWKSVANLQNVQPIAPDQLNTYDVLNSDDVVFSVEALNAFVHGPTEAAQEESK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS18_MYCPN
Sequence: MMNNEHDNFQKEVETTTETTFNREEGKRMVRPLFKRSKKYCRFCAIGQLRIDLIDDLEALKRFLSPYAKINPRRITGNCQMHQRHVAKALKRARYLALVPFVKD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PIM2_DANRE
Sequence: MLDKRIVDVRLDQLEILKAKNGKEHFEKQYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQSLGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFEKPQHCQDLFDFITERGALDESLARRFLKQVIEAVQFCHSKGIVHRDIKDENILVDTRTGDIKVIDFGSGATLKDSMYTDFEGTRVYSPPEWILYHKYHALPLTVWSLGVLLYDMVCGDIPFEQDTDIVKAKPSFNKRISNDCRSLICSCLSYNPGDRPSLEQILQHPWMMESSVDNGDLQEESKIKPSL
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase pim-2, Kinase pim-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
Protein: EFG_ECO5E
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.