PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_VIBPA
Sequence: MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGADWLHLVDLTGAKDTSARQLDLIAKLLASTPANIQIGGGVRTEQDVVDLLEAGAQRVVVGSTAVKQPELVKGWMEKYGAEKIVLALDINIDQDGTRKVAISGWQEDSGVTIEALINDYLTVGLQHVLCTDISRDGTLEGSNVELYVDLCKQYPQVQFQSSGGIGSLADIEALKGSGVAGVIVGRALLDGKFTAEEAFACWQSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM38A_XENTR
Sequence: MELLSALSLDDLAVAFSKLPVFPLFDVAYYIISILYLKYEPGAVDLSKRSPVASWLCAMLYCFGSYILADVLLGESPIHYFSNNANILLASAVWYLTFFCPLNIFYKIVSFLPLKLVLVGMKEVVRVRKIAMGIHHAHHHYHHGWVIMVLIGWVKGSGVALMSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQAHWLPISKAYLIFFFTLFMAICKIYMTATHSHGSPFAIFESGICCVLFGAANGDHDDHGDHHHHHDDHDVSHSTVKSKEELNEGTRKRKTKKAE
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type A, TRIC-A, TRICA, Transmembrane protein 38A.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane.
Protein: H16S1_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCCKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1s, U11-TRTX-Hhn1s, Hainantoxin-XVI-19, HNTX-XVI-19.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FZO_DROME
Sequence: MAESDSGESTSSVSSFISSSSSSRLSEFVDAKTELQDIYHDLSNYLSNFLTILEETVLLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLAVSALKTKFGPHLLSAQKILNQLKSTLICPFIEKVSRLIDENKERRANLNAEIEDWLILMQEDREALQYCFEELTEMTQRVGRCVLNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLCAHLDKLLEDRVLQCLSIPLQRKILDIEKEIGLPIAENSCDWQLIYGLDCQSYMSDFQPDLRFRFSLGFTALWHRLEGNLPLHASPFRIQKLQNGHKKCSPLPPLVNGNHWQMLESLVKSKGSLGTVLLSAMAIRSFNWPIVLILGGLVGSFYIYEYAAWTTAAQERSFKSQYARLLQQRLRSDVQQTVSGFELQLRQHLATVRNCWEAQSNETLNDLNVRTAELTKQIQSMEVLQLSLKKFRDKGQLLASRLGDFQETYLTKS
What is the function of this protein?
Essential transmembrane GTPase, which mediates mitochondrial fusion during spermatogenesis (PubMed:9230308, PubMed:18799731).  In early spermatocytes, fusion of mitochondria give rise to two organelles named Nebenkern and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (PubMed:9230308, PubMed:18799731).  Essential for fertility (PubMed:9230308).
What are the official names of this protein?
Transmembrane GTPase fzo, Protein fuzzy onions.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: ARMC1_MOUSE
Sequence: MNSSSSTMNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNLADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDAPVEVEENTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW
What is the function of this protein?
In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
What are the official names of this protein?
Armadillo repeat-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Note=Associates with the outer mitochondrion membrane, most likely through its C-terminus (By similarity). Not integrated into the mitochondrial outer membrane (By similarity).
Protein: TTCA_ANASK
Sequence: MQQIHRLERKLLRATAEAIRDFDLVSQGDRIMVAVSGGKDSYTLLHLLMRLRERAPIDFDLVAVNLDQGQPGFPAQVVEDHLRSVGVPYRMLQRDTYSVVRRLVPEGKTTCPVCSRLRRGVLYNAAVEMGCTKIALGHHRDDLVETLLLSALYSGALKSMPPKLRSRDGRNVVVRPLCYAAEEDVAAFAEAMRFPIVPCDLCGSQPNLRRKRVKRLLAELSAEHPAVKGNLLHALAHVVPSHLLDRDLHRQLADATGRDPWLDAEDEEAEDCGEPSAGDGVVSLGGARGGR
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_NITEU
Sequence: MSESISHQLQLIRRGCQELLIEEEFAQKLAQGRPLRVKAGFDPTAPDLHLGHTVLLNKLRQLQDLGHHILFLIGDFTGMIGDPSGKSATRPPLTREQITQNADTYASQVFKILKPEQTEVVFNSSWMDKFSAADVIRLAATYTVARMLERDDFSKRYHENRPIAIHEFLYPLVQGYDSVALKADLELGGTDQKFNLLVGRELQKHYGQPPQCILTMPLLEGLDGIQKMSKSLNNYVGINESPAEIFGKLMSVSDTLMWRYIELLSFESLETVRQWQNEVESGCNPREIKMRFAREIVARFHSQTDAVRAAEEFEARFSKGVIPDDIPEKKLYIQDAGLALPQLLKLAGLTASTSEALRMIEQGGVKLNGDKVSDKTRIIPSNVTVIAQIGKRKFAKVTLVTEQSGKQAN
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_MYCGI
Sequence: MIEAIRIGIGGPVGSGKTRLVETLVPRLSAAGLSVAVITNDLVTDEDAQRVRRSGVIDPERVLAVETGACPHTAIREDPSANLAAAERLNRRFGDLDVILIESGGDNLAATFTSDLVDYWIFVIDTAAGDDIPRKKGIGLLQADLLVVNKIDLAALVGADLDMMRRDCAIARPVKPTVFTDLKSGHGLIELTERLIDGAMLGVGVP
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMAD7_HUMAN
Sequence: MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR
What is the function of this protein?
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access (PubMed:21791611).  Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex.  Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation.  Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
What are the official names of this protein?
Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Interaction with NEDD4L or RNF111 induces translocation from the nucleus to the cytoplasm (PubMed:16601693). TGF-beta stimulates its translocation from the nucleus to the cytoplasm. PDPK1 inhibits its translocation from the nucleus to the cytoplasm in response to TGF-beta (PubMed:17327236).
Protein: ISPE_LIGS1
Sequence: MEISEKAPAKLNLSLDTPFRHQDGEPEWRMVMTAIDLSDYVHIKTIPNSKEITVQTNTGFLPCDQRNLAYQAAKLLQSKLDKPEGVEIEIDKHIPVSAGMGGGSADAAAVLRGLNKIWNLNMSREELAKLALTIDSDVPFCVYSEPALVTGRGEKITPIGPLPPMWLVIAKPQASVSTPTILRQIHEQHLNHQEVQNVVSAIKQQDFDKMCRHMGNALEPITMKKCPDIIKIKDKMLQFGADAAQMSGSGPTVFGISQKKSRATHIYNSLRGFCKEVYLVRALDSLTTK
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HSP74_LEIMA
Sequence: MSSTKHRIDLGTTYSCVGVFKNEQVDIIANDQGNRTTPSYVAFTETERLIGDARRTRWHEPPGNTVFDEAHDRPQVRRPDLQSDMKHWPFKVIVKDGKPVISVEYQNQTKTFSRGDLGYGAAENEGDGGGYLGTTVKDAVITVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAAIAYGMDRKGDKGEKNVLIFDLGGGTFDVTLLTIESGVFEVKATAGDTHLGG
What are the official names of this protein?
Heat shock 70-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CAPZA_DEBHA
Sequence: MSSSVGLDTIVSSLVKSSPPGELDGISQDLSAILSSKSNSSTVNTAIEKYINENSGVFSSTYIASKINKHESSTKYIDFIGKKLFNIDLHKQTAIDFEDYEPEVKYPAYFDELVKKLTEYGEDHYPSKYAFTIVPDGSDLQIIIIGQKLNYENFYTGLWKSHYKIKSGSIEGEAKLDIHYYEDGNVRLNFEESTSGTLSSSNASEIVNFINNAENEMTLKIVEDFNELNQKYFKNLRRLLPVTRSKINWGQAIGNYRLGSDVVHNK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Septum.
Protein: SLYX_SHEDO
Sequence: MQELQQKIEDLETKLAFQELSVEELNQEVIKLNQLVAKQQQQISLMVNKLMDIEPSNMASESEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: NUOA_PROMH
Sequence: MSMSTTTEVIAHYWAFAVFLIGALGLCSLMLLGARYLGGRAQARAKHVPYESGLDSVGSARLRMSAKFYLVAMFFVIFDVEALFLYAWAVSVREVGWLGFIEAAVFIAILLAGLFYLVRIGALNWTPVRSRRETAGKSHVRLTSGKHPQQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_BURM9
Sequence: MVIIRLARGGSKKRPFYNIVATDSRNRRDGRFIERVGFYNPVATKGEALRIAQDRLTYWQGVGAQLSPTVERLVKQAQKAQPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL29_CLOB1
Sequence: MKARELQELRKSSPQELQSKLNDLKAELFNLRFQLATGQLENPMRIREVKKSIAQIKTILREEEIRAYQQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYP_SULIY
Sequence: MQITRDKWSKNFSEWFDWVLREGEFYDYGRYPVKGMGVWMPYGFKLRQNIISIIRNLLDSTGHEEVLFPLLIPEDLLRRESTHIKGFEEEVFWVTKGGSEDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQRQVEEAIEIYKKIFNNLAIPYVLSERPEWDRFAGALHTYAFDTIMPDGKVMQIGTVHHLGQNFSRALDFKIQKKDGSLDYPHQTSYGISDRAIASVIAIHGDDHGPILPPSVAPIKVVVVPIPAKNEEGTQQVMKYSIEICEMLNKNNITCVTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELASSTVFIKRRDNLKSYTVKKEEVVNKVKEVLNEIQEDLRKRAWESLKSRIEYANDIEKAKNILENNSGIVDVPWCGSKECGLKIEELTNARVLGYPIEDRKVNDKCVICKMNAKTVLRVAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_YERPG
Sequence: MALNLQGKQAIVAEVKEVAKGALSAVVADSRGVTVDKMTELRRAGREAGVHMQVVRNTLLRRIVEGTPFECLKDTFVGPTLIAFSAEHPGAAARLFKAFAKDNAKFEVKAAAFEGELIPAAQIDRLATLPTYEEAIARLMGTMKEAAAGKLVRTLAALRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: T1S_SALPO
Sequence: MNRGKLPEGWATAPVSTVTTLIRGVTYKKEQALNYLQDDYLPIIRANNIQNGKFDTTDLVFVPKNLVKESQKISPEDIVIAMSSGSKSVVGKSAHQRLPFECSFGAFCGALRPEKFISPNYIAHFTKSSFYRNKISSLSAGANINNIKPASFDLINIPIPSLAEQKIIAEKLDTLLAQVDSTKARLEQIPQILKRFRQAVLAAAVSGTLTTALRNSHSLIGWHSTNLGALIVDSCNGLAKRQGLNGNEITILRLADFKDAQRIIGNERKIKLDSKEENKYSLENDDILVIRVNGSADLAGRFIEYKSNGDIEGFCDHFIRLRLDSNKIMSRFLTYIANEGEGRFYLRNSLSTSAGQNTINQTSIKGLSFLLPPLKEQAEIVRRVEQLFAYADTIEKQVNNALTRVNSLTQSILAKAFRGELTAQWRAENPDLISGKNSAAALLEKIKAERAVSGGKKTSRKKA
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates A-2 on the top strand and A-3 on the bottom strand of the sequence 5'-AACN(6)GTRC-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated (PubMed:3025838, PubMed:12654995).  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (By similarity).
What are the official names of this protein?
Type I restriction enzyme StySPI specificity subunit, S protein, Type I restriction and modification system SP, Type I specificity subunit S.StySPI, S.StySPI, Type-1 restriction enzyme StySPI specificity subunit.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: YR661_MIMIV
Sequence: MVIYNILMDLRIVKNENCTDDLDYQSHTNNVHNEFLKNIMCQDCFKTKNNCLCKNIHECKTIKPRKICEYCNEIYIKKKIIKGKNSIQIKWQCPKSHQSGSHCKKCMSQLINGECRNYDCNCGKDGSCCQICGLMYKYGKCINGHDDSNKCDYCGMIYVDGVYLCGHNGDICEECVLLKEHGFCPLVDEHNKCSGEISTNYFNDNYDEMDITIHDYLI
What are the official names of this protein?
Uncharacterized protein R661.
Protein: Y1533_STRPS
Sequence: MKILIPTAKEMNTDLPSIEATPLKPESQAVLDALALYSASQLESFYKVSAEKATEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHVFITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSSEFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLSQPQGLVFVKEV
What are the official names of this protein?
UPF0246 protein SPCG_1533.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL17_MYXXD
Sequence: MRHKVGQRKLHRSTSHRLAMLNNMVTSLLEHQAIRTTLPKAKEARKIAERIITLGKRGGLANVRLAARTVKDRDVLQKVFGEYKDRYASRPGGYTRIVRLGFRRGDAAEMALLELVDRPEKAAPVDTEAAAPAEETKAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GRPE_BORHD
Sequence: MEEKKRCEESEKIKEQENETLPNEDSPSMGKKVAELENEISNLKDLYLRKQAEFENFRKRLEKDKENFIKFANENIMKDIINFLDNLERAIDSSKQSKDFDTLLSGISMIESEVLSSFDKKYNLKKFGKPGEDFDPSQHEAISIEEKEGVKTPEIVEVYQKGYCYNNRVLRTAKVKVAQSKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT1_HORVU
Sequence: MSCSCGSSCGCGSNCNCGKMYPDLEEKSGATMQVTVIVLGVGSAKVQFEEAAEFGEAAHGCSCGANCKCNPCNC
What is the function of this protein?
Possibly relevant to mugineic acid-family (MAS) phytosiderophore production in iron-deficient barley roots.  May have a function at the regulatory region of MAS synthetic genes or Fe(3+)-MAS transporter gene by conjugating with Fe(2+) like FUR protein.
What are the official names of this protein?
Metallothionein-like protein 1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: TEAN2_BOVIN
Sequence: MDKFVIRTPRIQSSPQKKDPGGKIYKQATIESLKRVVVIEDIKRWKTMLELPDQSKENLVEALRELKKKIPSREVLKSTKIGHTVNKMRQHSDSEVACLAREVYTEWRTFIEKHVNRPSIEVRSDAKTETFRKNAQKLLSEALELEMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIREQVKSGMLPVGTFVQTHKK
What are the official names of this protein?
Transcription elongation factor A N-terminal and central domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TCEANC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IAP_GVCPM
Sequence: MSDLRLEEVRLNTFEKWPVSFLSPETMAKNGFYYLGRSDEVRCAFCKVEIMRWKEGEDPAADHKKWAPQCPFVKGIDVCGSIVTTNNIQNTTTHDTIIGPAHPKYAHEAARVKSFHNWPRCMKQRPEQMADAGFFYTGYGDNTKCFYCDGGLKDWEPEDVPWEQHVRWFDRCAYVQLVKGRDYVQKVITEACVLPGENTTVSTAAPVSEPIPETKIEKEPQVEDSKLCKICYVEECIVCFVPCGHVVACAKCALSVDKCPMCRKIVTSVLKVYFS
What is the function of this protein?
Acts by blocking cellular apoptosis rather than by preventing viral stimulation of apoptosis.
What are the official names of this protein?
Apoptosis inhibitor IAP.
Protein: ISPE_XANC5
Sequence: MDRIALMDASGRDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTVHLRVRRDGQIRRLGESLPGVSEDDDLVTRAARLLQSAAGTQAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLGLAADVLAELGLQLGADVPVFVRGRNAWAEGVGEQLTPISLPEAAYLLVDPGVHVPTPALFRSQELTRDAALAKIADFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLTGSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDALDATQV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CRYL1_PONAB
Sequence: MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGMKHVLKTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQWRDECLMRLAKLKSQVQPQ
What is the function of this protein?
Has high L-gulonate 3-dehydrogenase activity.  It also exhibits low dehydrogenase activity toward L-3-hydroxybutyrate (HBA) and L-threonate.
What are the official names of this protein?
Lambda-crystallin homolog, L-gulonate 3-dehydrogenase, Gul3DH.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMKN_HUMAN
Sequence: MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGVADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIEGADASSLQKRAGRDDQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWVKFW
What is the function of this protein?
May act as a soluble regulator of keratinocyte differentiation.
What are the official names of this protein?
Dermokine, Epidermis-specific secreted protein SK30/SK89.
What is the protein family that this protein belongs to?
Belongs to the dermokine family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y110_ABVP
Sequence: MNTQNIVEKTHEKFSSTWSYLEQTSTDLKQNLRSRLLGLDSLLRELYKQETDEKKKMYIFYALMYVDSALDNLDYMNPEHDPFAVFQAKWAVQKAFEIFSDLFKDYFKSD
What are the official names of this protein?
Uncharacterized protein ORF110.
Protein: DNAJ_GEOSE
Sequence: MAKRDYYEILGVSKNATKEEIKKAYRKLSKKYHPDVNKEPDAAEKFKEIKEAYEVLSDDQKRAHYDQFGQADPNQGFGGFRSDDFDLGGFSGFGGFEDIFNTFFGGGRRRNPNAPRAGADLQYTMTLTFEEAAFGKETDIEIPSEETCNTCHGTGAKPGTKPETCPHCHGAGQISTEQSTPFGRIVNRRTCPYCGGTGQYIKEKCTTCGGTGRVKRRKKIHVKIPAGIDDGQQLRVAGQGERGLTVGRREIYILSFMWSRMSFLNVTAMIFIAKCRLRLRKLRLGMKSKSRPFTGKLKLKIPAGTQTGTRLRLKGKGVPNVRGYGYGDQHVIVRVVTPTKLTEKQKQLLREFDQLGGSSMHHEPHDRFFDKVKKAFKPES
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.