PharMolix/UniProtQA huggingface dataset:
Protein: TXF3C_SCODE
Sequence: MEKKIIFLVVLVALLALPEFISSEVIKRDIPYKKRKFPYKSECLKACAAAFTGGDESRIQEGKPGFFKCTCYYTTG
What is the function of this protein?
Voltage-gated calcium channel inhibitor (Cav) (8. 6% block at 10 nM), when tested on DRG neurons.
What are the official names of this protein?
Omega-scoloptoxin(15)-Ssd3c, Omega-SLPTX(15)-Ssd3c, Toxin SSD1052.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-15 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU_MARMM
Sequence: MAKEKFERTKPHANIGTIGHVDHGKTTLTAAITMVLAEASGGTAKGYDEIDSAPEEKARGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLARQVGVPALVVFLNKVDQVDDEELLELVEMEVRELLSSYEFPGDDLPIVAGSALAAVEGRDDHIGKDKILELMAAVDEYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRIERGVVKVGEEIEIVGVRDTTKTTCTGVEMFRKLLDQGQAGDNVGVLLRGVDREGVERGQVLAKPGSITPHHKFVAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVTLNEGTEMVMPGDNIEMNVELIVPIAMEEKLRFAIREGGRTVGAGVVSKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPCS3_CAEEL
Sequence: MHNLLSRANALLAFTLWVMAAVTAACFLSTVFLDYTVPTKLTVNDVKVRNVVDYATDEQQADLATLNFNLKVDFSKIFNWNVKQLFVYLVAEYKSKVNEVNQVVLWDRIVERADRVVMDEIGVKSKYYFLDDGTNLLNHKNVTFVLRYNVIPNSGYLRLVQSSDQVVVPFPTTYTTTRRS
What is the function of this protein?
Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 3, Microsomal signal peptidase 22 kDa subunit, SPC22, SPase 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ARCH_THEKO
Sequence: MRKWEHYEHTADIGVRGYGSTLEEAFEAVALGLFDVMVNVKKVEPKECREVEVEEEDLEALLYSFLEELLVLHDMEGLVFGDVKVRIEKTENGYKLKAKACGEVLNPEKHEPKEEVKAITYHDMKIEKLPDGRWMAQFVPDL
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: RTEL1_DROPS
Sequence: MPESVIAGIPVHFPFEPYNVQRDYMEKVIICLRDGTNGVLESPTGTGKTLSLLCASLAWIRTRQSEHQQQMIKLKATSKEGGPGSGPGGDLSELAMTVGQANNWGVPKVIYASRTHSQLNQAMRELKRTAYANMRSVVLGSRDQLCIHPEVMKEQGNSNKVNLCKLRVHSKTCTFQLRVESKKDHPDFRGPSIMDIEDLVRVGQKLKMCPYYASKELVAQADITFMPYNYLLDPKARKANKIELGNTIIILDEAHNIEKICEESASVQIRSSDVAMAIEDVTHIMKVFTSGESQEAGGDEPKDFTLDDLTLLKEMLLELEKAIDAVVVDNPTDGTTYPASLMYELLGKANFTYGNCATIVALLDKLVQYLMVASQHMTIRKGGTFTMLSDLLTIVFANKENIMSKVHLSFKVHVQVEESNKQQGKSGATQGKQQGWLGKGNITTTGTSSKAAKIVNFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDRQQLISNFKNRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKPIFVEPRGKDQFTSTMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLETNRTKENQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFQDASQVQQLSKWIRGHLGARPQSSPFGPIVRELRQFFKHAEETMKQPDVREEEQPLMNVCKVEEVGTLPVIPTIKQEPGNNATFRKANKSAIKVEMANSINSWTPADYASAAGRTLGKAAPNAMDFMSRLDSNVSSIDFNCSGSADSGSGGCGSSSLVTIHKRERSSPGVTDTVATQTTKKRYKLAENIKTEPKSNSSQQVKVAPESRADFLRELRSLISQDQFRDFGKVLIEYRSGTDENFESLMTVLLDVLAAPKMRYLFIGMRRFLRNEHKAEFDVRLASLNLAQESSPNKRIP
What is the function of this protein?
ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
What are the official names of this protein?
Regulator of telomere elongation helicase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_PHOLL
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDSVEVKVWVVEGAKKRLQAFEGVVIAIRNRGLHSAFTVRKVSNGEGVERVFQTHSPVVDSINVKRRGAVRRAKLYYLRERSGKAARIKERLNSK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: GLMS_XANAC
Sequence: MCGIVGAIAGRDVVPVLIEGLKRLEYRGYDSSGIAVLDGAQVRRVRRTGRVAEMAQAAQAEQLGATLGIGHTRWATHGGVTEANAHPHISAGVALVHNGIIENHEAQREKLRALGYTFESQTDTEVIAHLIHHHLGSAGDLLTALQHTVKELTGAYALAVVSQAEPERFVCARMGCPLLIGVGEGENFVASDVSAIVQATRQVIFLEEGDTAELRRDGVRIFDGNDAPVERPLHLSDVSLASLELGPFRHFMQKEIHEQPRALADTIEAAIDAKGFPASLFGANAEAVLRDIEGVQILACGTSYYAGMTARYWIEAIAGLPCSVEIASEYRYRAAYANPKHLIVTISQSGETLDTMEALKYAKSLGHLHTLSICNVPESAIPRASELVCYTRAGAEIGVASTKAFTTQLAVLFQLTMVLGTLQGRISDAEEAEYLEQLRFLPGSVQHALNLEPQIMAWAERFSPKENALFLGRGLHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVDAAMPVVVIAPNDRLLEKVKSNMQEVRARGGELFVFADQDSHFSDSEGVHVIRTPRHAGVLSPVIHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB4B_HUMAN
Sequence: MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-4B chain, Tubulin beta-2 chain, Tubulin beta-2C chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y821_SYNY3
Sequence: MVSPALPRLSNPLFFANIMTVKVLIPTPLQKFTSGQATIDCEAANVGQLIEALEANCPGIKARLCDEEGKPRRFLNFYVNEEDIRFLEGTDTALSAGDEVSIVPAVAGG
What are the official names of this protein?
Putative sulfur carrier protein slr0821.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein CysO family.
Protein: Y618_POLAQ
Sequence: MAGHSKWANIQHRKGRQDEKRGKIWTKLIKEITVAAKMGGGDLTANPRLRLAIDKAKDANMPNDNVQRAIQRGTGSLEGVNYEEIRYEGYGMNGAAIIVDCLTDNRTRTVAEVRHAFNKNGGNMGTEGSVAFLFKHCGQMLFAPGTSEDQLMEVALDAGAEDVITHDDGSLEVLTPVPDFSKVQDAISQAGLKAELATVAMRPETEIALEGDQAESMQKLLDALENLDDVQEVFTNAAL
What are the official names of this protein?
Probable transcriptional regulatory protein Pnuc_0618.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESSA_STAAM
Sequence: MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTLFNKDSKEVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESDKSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI
What is the function of this protein?
Component of the ESAT-6 secretion system (Ess).  Required for the secretion of EsxA and EsxB.
What are the official names of this protein?
ESAT-6 secretion machinery protein EssA.
What is the protein family that this protein belongs to?
Belongs to the EssA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSGA_SYNS3
Sequence: MVVLDQPAQSGMVVALQANYLEVELDQVSELIPSRLLCTRRTRLSHRGEAVYVGDRVRVEAIDVSHARAVVADVEPRVSFLTRPPVANASTVVVALAVDQPAFDPDQASRFLLTAERTSLAVQLVLTKTDLLEPEALERLRVRLQAWGYPPLLVSTFSGLGLSELKQRLAESSLSVLCGPSGVGKSSLLNALIPELDLRIGSVSGRLQRGRHTTRHVELHHLGAKARVADTPGFNRPDLPDDPRNLEVLFPELRVQLEQHPCRFRDCLHRDEPGCGVTRDWERYPIYRRAVEDLLGLSRPSRGG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXLA6_CYRSC
Sequence: MKTSMFLTLTGLVLLFVVCYASESEEKEFPKELLSSIFAADSDFKVEERGCLGDKCDYNNGCCSGYVCSRTWKWCVLAGPWRR
What is the function of this protein?
Agglutinates erythrocytes.
What are the official names of this protein?
U5-theraphotoxin-Hs1a 6, U5-TRTX-Hs1a, Lectin SHL-Ia6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TTI2_YEAST
Sequence: MTAVTDIIDELNDSSLSSTRLRELCLQLRKKTDTGCAITVSDEVNLIESLSYHSISPGVDIQINTDVLQTIDYYFQRNKSEHDEIMCVLISKLQPLLLKRKSNFELKEQRNLGLKPTLGMSLKEDNLMQAWVSQGGLKGIPLFYVILLHLKRRDISTNLSWIIPGILNILDDTTDIRRIKLRGVLLLQTLLNHTFMNETNDSKWIQFSSTGLFPLFEKTLINMCYFLPPSYNADETIAIWRVVFPTIQSLYKVEFLDNYTKYQYHLEKFMSEIILQNIIPRASLAYENLTLYALECTMNILRLQREGSVVHLQRLIFVLGEYIVRNPFYTTFPKLISKTLSVVSTLIKVCPNERIVAHRFDILSLILVTYDKCSQEDALNESILQQCKETISWLLNCDCAMGEQLSTLSKQPRFQLLFEFS
What is the function of this protein?
Component of the ASTRA complex probably in chromatin remodeling.
What are the official names of this protein?
TEL2-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the TTI2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GREA_BUCA5
Sequence: MINLIPMTVRGAEKLRRELKKLKSINRPRIIAAIAEAREHGDLKENAEYHSAREEQSFCEGRIKEIELKLSNSQIIDVTKISNNGRVIFGSTVSILNIKNNEKFTYRIVGDDESDFKKNLISINSPIARGLIGKEINDVVIICTPGGDVEYKILKINYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TCEA3_BOVIN
Sequence: MGQEEELLRIAKKLEKMVARKKTEGALDLLKKLGSWQMSIQLLQTTRIGVAVNGVRKHCSNKEVVALAKVLIRNWKQLLDSPATPKGEKGEERVKAKKKEKGLDCSDWKPETSLSPPRKKRVEEPKDRRDSVDSKSSATSSPKRPSMERSNSSKSKAETPRTPSSPSSPTFAPSVCLLAPCYLTGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
What is the function of this protein?
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity).
What are the official names of this protein?
Transcription elongation factor A protein 3, Transcription elongation factor S-II protein 3.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OR5R1_HUMAN
Sequence: MAEVNIIYVTVFILKGITNRPELQAPCFGVFLVIYLVTVLGNLGLITLIKIDTRLHTPMYYFLSHLAFVDLCYSSAITPKMMVNFVVERNTIPFHACATQLGCFLTFMITECFLLASMAYDCYVAICSPLHYSTLMSRRVCIQLVAVPYIYSFLVALFHTVITFRLTYCGPNLINHFYCDDLPFLALSCSDTHMKEILIFAFAGFDMISSSSIVLTSYIFIIAAILRIRSTQGQHKAISTCGSHMVTVTIFYGTLIFMYLQPKSNHSLDTDKMASVFYTVVIPMLNPLIYSLRNKEVKDASKKALDKGCENLQILTFLKIRKLY
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 8U3, Olfactory receptor 5R1, Olfactory receptor OR11-185.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM3_SYNC1
Sequence: MSSSALRIGTRASRLALWQAEWVQQQLETLHPGLSVVLVPITTKGDKILDVPLAKVGGKGLFVKEIEEALYDGSIDLAVHSMKDVPSVLPPGLILPCIPPREDPRDALVTPDGRSFAQLPQGARIGTSALRRQAQLLHRRPDLDIVSLRGNVETRLRKMEEEDMDGIVLAAAGLKRLELAERIAEYLSVDVSLPAIGQGALGLECREGDDRTLELIAPLHDADTAVAVRAERAFLRRLNGGCQVPLAAHATVAEQTLTMVGLVAEVDGGSLIKETLAAPVAQAEAVGCQLAETLLARGADRILAALDITPTPLVP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CBPYA_TRIVH
Sequence: MKFLTTGLLATAALAAAQEQHVLQAEDGHGQAPQRDASIFDETLQKFQSSLEDGISHFWSEMKTNFKDYLPLISLPKKHTRRPDSEWDHVVRGADIESVWVQGADGEKRREIDGKLHNYDLRVKAVDPSKLGVDPGVKQYSGYLDDNDADKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPATIDKNLKVVSNPYSWNSNASVIFLDQPVNVGFSYSGSSVSDTVAAGKDVYALLTLFFKQFPEYASQDFHISGESYAGHYIPVFAAEILSHKNTNINLKSALIGNGLTDPLTQYPQYRPMACGEGGYPAVLDQGTCRSMDNSLERCLSLIETCYSSESAWVCVPAAMYCNSAILAPYQQTGMNPYDVRTKCEDMASLCYPQLNAITKWLNQESVMQALGVEVQSYESCNSGINRDFLFHGDWMKPYHRLVPSVLEKIPVLIYAGDADFICNWLGNLAWTDALEWPGHKKFAEAKLEDLKIVNNKDKGKKIGQVKSSGNFTFMRIFGAGHMVPLNQPEASLEFFNRWLGGEWH
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: VATA_CANTR
Sequence: MAGALENARKEIKRLSLDDTNESQYGQIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRINGDKATIQVYEETAGVTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKDESQSIYIPRGIDVPALSRTVQYDFTPGQLKVGDHITGGDIFGSIYENSLLDDHKILLPPRARGTITSIAEAGSYNVEEPVLEVEFDGKKHKYSMMHTWPVRVPRPVAEKLTADHPLLTGQRVLDSLFPCVQGGTTCIPGAFGCGKTVISQSLSKFSNSDVIIYVGCFTKGTQVMMADGADKSIESIEVGDKVMGKDGMPREVVGLPRGYDDMYKVRQLSSTRRNAKSEGLMDFTVSADHKLILKTKQDVKIATRKIGGNTYTGVTFYVLEKTKTGIELVKAKTKVFGHHIHGQNGAEEKAATFAAGIDSKEYIDWIIEARDYVQVDEIVKTSTTQMINPVHFESGKLGNWLHEHKQNKSLAPQLGYLLGTWAGIGNVKSSAFTMNSKDDVKLATRIMNYSSKLGMTCSSTESGELNVAENEEEFFNNLGAEKDEAGDFTFDEFTDAMDELTINVHGAAASKKNNLLWNALKSLGFRAKSTDIVKSIPQHIAVDDIVVRESLIAGLVDAAGNVETKSNGSIEAVVRTSFRHVARGLVKIAHSLGIESSINIKDTHIDAAGVRQEFACIVNLTGAPLAGVLSKCALARNQTPVVKFTRDPVLFNFDLIKSAKENYYGITLAEETDHQFLLSNMALVHNCGERGNEMAEVLMEFPELFTEISGRKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKATALGSPDRVGSVSIVAAVSPAGGDFSDPVTTSTLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKYYDSNYPEFPQLRDKIREILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSSYDAFCPIWKTFDMMRAFISYYDEAQKAIANGAQWSKLAESTSDVKHAVSSAKFFEPSRGQKEGEKEFGDLLTTISERFAEASE
What is the function of this protein?
VDE is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates 'homing', a genetic event that converts a VMA1 allele lacking VDE into one that contains it.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, Vacuolar proton pump subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Note=Membranes of various intracellular acidic compartments.
Protein: UREF_ALKEH
Sequence: MSTETNPGLAQRRLWQLISPTLPIGAYSYSAGLEYAVEAGWLRNADAVADWLQGQLHHALAPVDIPALARLHAAWQSDDAVAVHYWSQWLRACRETKELREEDRHVGQALARLLRDLDLPEAAPWVDDPIAGWPTLYALAVARWAIPLETAAEAYLWAWCENQVSAAIKLVPLGQTAGQRLLLEMAEPVGEAARQGLALEDEEMGGGLPGVALASSLHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM27_YEAST
Sequence: MKGSPISQFSKTSINALTRPWKKYRDGELFYGLSKVGNKRVPLTTKQGNKTMYKGTRASGIGRHTKFGGYVINWKKVRTYVTPDMVNFELKPYVNANVPPLKHEFKGFSGGPLDPRLQLLKIKEYIVNGRVQSEGATDTSCYKERG
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L27, mitochondrial, Mitochondrial large ribosomal subunit protein mL41, YmL27.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL41 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: GLUQ_NEIG1
Sequence: MYTGRFAPSPTGLLHIGSLLTAVASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTLEAFGFKWDGEVTYQSRRYALYEETLYRLKTAGLVYPCHCNRKDWQAGARRGTDGFVYNGRCRHPGQRPALQGKQPSWRIRVPDRDIGFSDGIVGSYAQNLARDIGDFVLFRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTLAPALDLNRREQLLRQVFRYLKLPEAPETDRPAELLDWAVAHWDMDKVPKHAITAP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: DSBB_VIBCH
Sequence: MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAALIGAIAPQNPVVRWLGFAAWGASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLNQWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLALAIFVVAQLAKTSR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSHL_CHLTA
Sequence: MKGKKYYSDYHVWIEPIHSRIVKLGLSSQMREHLGNILHIDLPSLGAFIKEGEKLCILESSKSAIEVLSPVSGEVLEVNTALEDDILPVNNATESEGWFVVLQLTEDFRSESFSLEP
What are the official names of this protein?
Glycine cleavage system H-like protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: G2OX8_ARATH
Sequence: MDPPFNEIYNNLLYNQITKKDNDVSEIPFSFSVTAVVEEVELPVIDVSRLIDGAEEEREKCKEAIARASREWGFFQVINHGISMDVLEKMRQEQIRVFREPFDKKSKSEKFSAGSYRWGTPSATSIRQLSWSEAFHVPMTDISDNKDFTTLSSTMEKFASESEALAYMLAEVLAEKSGQNSSFFKENCVRNTCYLRMNRYPPCPKPSEVYGLMPHTDSDFLTILYQDQVGGLQLIKDNRWIAVKPNPKALIINIGDLFQAWSNGMYKSVEHRVMTNPKVERFSTAYFMCPSYDAVIECSSDRPAYRNFSFREFRQQVQEDVKKFGFKVGLPRFLNHVY
What is the function of this protein?
Catalyzes the 2-beta-hydroxylation of gibberellins (GA) precursors, rendering them unable to be converted to active GAs.  Hydroxylates the C20-GA GA12 and GA53, but is not active on C19-GAs, like GA1, GA4, GA9 and GA20.
What are the official names of this protein?
Gibberellin 2-beta-dioxygenase 8, GA 2-oxidase 8, Gibberellin 2-beta-hydroxylase 8, Gibberellin 2-oxidase 8.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
Protein: STE4_SCHPO
Sequence: MGDSDDFYWNWNNEAVCNWIEQLGFPHKEAFEDYHILGKDIDLLSSNDLRDMGIESVGHRIDILSAIQSMKKQQKDKLQQENKDQELKNIEESYKKLEEKTEHLSDDNVSLEKRVEYLETENTKLVKTLNSLNSEFLQLLRKIAINVKEGRQLTTENSSDTSSMTHPVQPSPSVLGSFDLEVNDSLTNAEKNRKLNVNLTYNEVLCSMLQRYRIDPNTWMSYDLLINYDDKEHAIPMDVKPLQLFRNLQKRGKSPSFVLSRRSC
What is the function of this protein?
Essential for mating and meiosis.
What are the official names of this protein?
Sexual differentiation protein ste4.
Protein: QUEA_XANAC
Sequence: MKKSDFHYDLPDELIAQAPLAERAASRLLVVPPSPQALADRQVRDLPELLQPGDLLIFNDTRVIPARLFGQKASGGRVEILIERLLGERQARVQIGASKSPKAGSLIALDAGGQAEVLGRDGEFYLLRFEIPTPLEHWLLEAGRLPLPPYIRREPGVEDRERYQTVFAREVGAVAAPTAGLHFDEPLLARLRERGVEFGHVTLHVGAGTFQPVRVDKLDQHVMHKEWLNVGAALVEQVRRTRARGGRVIAVGTTVVRSLESAWRKTEAAPEGELQPFAGETQIFILPGYRIRSVDAMVTNFHLPESTLMMMVSAFAGRERIFAAYHHAIAQRYRFFSYGDAMLLWGRESGLGNGES
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.