PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_ACICJ
Sequence: MNAISGGLNKVSFTNRKRIRKSFGRIPETTPMPNLIDVQRASYDAFLQMHVSPDSRTNSGLQEVFKSVFPIDDFAGRGRLEFVYYELEEPKYDVEECIQRGMTYAAPLKVVLRLIVWDVDEDTGARSIRDIKEQPVYMGDMPLMTDNGTFVVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKYLFAARVIPYRGSWLDFEFDAKDLIYVRIDRKRKLPVTTLLYALEGRATEALRAAREAKGESLEIGEIRGMDAEEILTYFYGKVPFTRTRTRDGETAWARPFEPETFRGAKLVEDLVDAETGEVVAKADDKLTARVARQIAVKTRTVLVSRADLIGRYVAEDLFDPNTGEIFADAGEEISEAKLKTFEDAGLDEIPTLAIDQAKGPWIRNTLAADKNASREDALIDIYRVIRPGEPPTSETAEALFRGLFFDAERYDLSAVGRVKMNMRLGLECEDTVRVLRKEDILRTIQIMCELKDGRGQVDDIDNLGNRRVRSVGELMENQYRIGLLRMERAIRERMGSVDIDGVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFAKVNKYGFIETPYRLVKDGKVLDEYKYLSAMEEERLTVAQADAPKLADGTLTEDLVSVRRNGDFRLVKPDEVTAIDVSPRQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLIKSDAPLVGTGMEAPVARDSGATIVARRAGVIDQIDGARIVVRATGEDGTTQGVDIYRLRKFMRSNQSTCINQRPLVRVGDRVGAGDIIADGPSTELGELALGRNVLCAFMPWNGYNFEDSILISERVAREDMFTSIHIEEFEVMARDTKLGQEEITRDIPNVGEEALRNLDEAGIVYIGAEVNPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLKLPPGVNGTVVDVRVFNRRGVDKDERALAIERAEIERLAKDRDDERAIQERAFLNRLREKLLGQVAGSGYKGVRSGTEITTELLAEIPRGAWRNLTVQDDRVMAEIETLKREFDASVHKLQQRFESKVEKLQRGDEMPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVVSKVVPIEDMPFLEDGTPVDVVLNPLGVPSRMNVGQILETHLGWACANLGRQIGEAVEAYQRDVAERERLHAMLKSVYGEEIYNEQIASMSDAELRELCGNIRKGVPIATPVFDGARITDIEDMLAKAGLDVSGQMTVCDGRTGEQFERKVTVGYMYMLKLGHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVSGRTKVYEAIVREQDNFEAGVPESFNVLTKELKSLGLNVDLNLSVD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TDH_ECOLU
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGVTRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SHIFL
Sequence: MAQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: MRAZ_LACGA
Sequence: MFMGEYHHNLDSKGRLIIPAKFRDEIGEKMVFTRGMEGCIFGYPIEEWQKIEAKLAKLPLTKRSARKFTRLFYSGAMESEFDKQGRVNLTMTLKEHAALIKECVIVGVSNRIEIWSAERWNDFSEEANENYDDIAEDLDDIEL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: WECG_KLEP7
Sequence: MDMTGTISAPLYLLRGLQLIGWRDMPHALDYLFADGALREGTLVAINAEKMLAVEDNPEVRALIEAAEFKYADGISVVRSLRKKYPQAQVSRVAGADLWEALMQRAGAEGTPVFLVGGKPEVLAQTESRLRQRWQVNIVGSQDGYFTPEQRQALFERIRDSGAKIVTVAMGSPRQEIFMRDCRRLYPHALYMGVGGTYDVFTGHVHRAPKFWQDLGLEWFYRLLLQPSRIKRQFRLLRYLRWHYSGKL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: CENPM_DANRE
Sequence: MALLSPYSKVPELNTATVLLVENEEELQNKLANAIVQHEKDFNVNVRLAKKLPLPVENKEARPRIDLIVFIVSLLSERSLQSAESSLSHLHSDCFLGKVCFLVTDARCGSHTQERLVSVRKLAASHHCPVICAEHRTADGVSAAALRLLNILQVSAGMTPMSTTALYLSTLTRCSLTSDLQEDYLQ
What is the function of this protein?
Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
What are the official names of this protein?
Centromere protein M, CENP-M, Proliferation-associated nuclear element 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres.
Protein: COBD_SORC5
Sequence: MTAAAALLVAVAFDLACGEPPAAVHPVVWMGSAIQALKRAAPAGGRAAELLFGALMALAVPCFFAALGAGVAALLAPHPVLALALSGLLLKPTFALRALRDAAYGVRDALEAGDVTGARGALRSLCSRDPSELDEPALVAASVESVAENASDSFVAPLFYFALFGLPGALFYRAVNTLDAMVGYHGRYEYLGKASARLDDALNFVPARLTALLLLAAGWLRGADARRGLAVLLRDGGLTESPNAGRPMAAMAGLLRVELEKRGHYRLGDPVEPLRRGLIDEACRIVVLATLLFAGLAAALLAAVSFGLGQELFR
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQEB_BACSU
Sequence: MLQNQSHTLIGVTKTAVFFLYAALAIIGFAIGYFIPQIAKWALSLPWIPLEGPLRLITSFQGSTASFITALLGMCAGIWFAHSVIAMLLSVKITDHTVEFIKGKKVQTIHSDDIALVFMDHKRLVLLGTAGYELVREEIDEKPVNVEKAFRQHHYEWATDGDPFKDQFRRWIPDAPDLSQGAHALLKARHKALQDEEKDDIEEFRLELAQLGIVVRDEGTRQYWRKAETYPPKIQLGEGL
What are the official names of this protein?
Uncharacterized protein YqeB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NNR_MYCLE
Sequence: MRHYYSVAAIRDAEASLLASLPDGVLMKRAAYGLASVIIRELAVRTGGVTGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRVHRKALVAFRKAGGRIVENVSAATDLVIDGVVGISGSGPLRPAAAAVFATVSASGVPVVAVDLPSGIDVVTGVINGPAVHAALTVTFGGLKPVHALADCGDVTLVDIGLDLPDSDILGLQAADVAAYWPVPGVHDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGSAYTQVLAHWPEVIASATPTAAGRVQSWVVGPGLGIDATATAALWFALETDLPVLVDADGLTMLAAHPDLVINRNAPTVLTPHASEFARLAGTPPGDDRVGACRKLADSFGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLAAGLPAAEAAAAAAFVHARAAALSAADPGPGDVPTSASRMVSHIRTALAAL
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: TRHO_LACLS
Sequence: MTQDYRVLLYYQYVPIEDGESFAQKHLSDCKALGLKGRILVADEGINGTVSGTVEQTNAYMSLMKNDSRFTSTIFKIDEAKQNAFKKMHVRYRPELVNLSLEDDVNPLELTGAYLDPKEFREAMLDENTVVIDARNDYEFDLGHFRGAIRPEIRSFRELPQWIRDNKEQFMEKRVLTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGDLWYGQMYVFDSRIAVPINQKEHVIVGRDWFDGSPCERYINCGNPECNRQMLASKENEAKYLGACSHECRVHPDNRYIKAHQLSNQEVQERLALLEKDLAS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RS8_EXIS2
Sequence: MVMTDPIADMLTRIRNANMVRHEKLEMPASTIKREVAEILKREGFIRDVEYLEDSKQGTLRVFLKYGASNERVITGLKRISKPGLRVYAKADEIPKVLGGLGIAIVSTSKGVMTDKEARQQKVGGEVIAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ABP4_MAIZE
Sequence: MVRRRPATGAAPRPHLAAVGRGLLLASVLAAAASSLPVAESSCPRDNSLVRDISRMQQRNYGREGFSHITVTGALAHGTKEVEVWLQTFGPGQRTPIHRHSCEEVFIVLKGKGTLLLGSSSLKYPGQPQEVPVFQNTTFSIPVNDPHQVWNSNEHEDLQVLVIISRPPVKIFIYDDWSMPHTAAKLKFPYFWDEDCLPAPKDEL
What is the function of this protein?
This is probably a receptor for the plant hormone auxin.
What are the official names of this protein?
Auxin-binding protein 4, ABP.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS7_TROWT
Sequence: MPRKGPVVRREIPEDPVYSSRVVSQLIGRVLLSGKKSLAQRIVYSALDKVSMKASEDPVSVLRKALDNVRPSLEVRSRRVGGSTYQVPVPVRSHRADALAIRWLTVYSRARREKSMVDRLASEILDASNGVGATVKCKEDTHRMAESNRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YIDC_HALHL
Sequence: MENQRLILLIALAGISLLLYFAWEREQMDPAEPVVEEQESEVDQEAPDAPSRAEEPDAGDPMAEGVVDPDDEDAKRVRVKTDLIEAEISTQGGDIRQLDLLKHQKASDDPTPYRLLRDEGEPLFVAQAGLGGDGPAPGRDARYEVDQDEFELAEGEDTLEVPLIWEEDGVKVRKVYTFRRDSYLVDVRHEVENNAEDDWAGFQYVQLRRRPDPAGTTPWYIHSFTGGSLYTQEDRFSRISFSDMEDSDLSQDERDGWAAMLQHYFLGVMIPERGETYRYYTRALPQETYLLGMSSPWLQVAAGESGQKTNHLFVGPKEQDRLTAVGSALDVDDLRLTVDYGFLTILANPLFWALDQIENLVKNWGVAILILTLLIKIAFYKLSAISYRSMAKMRKVQPKMQQIRERYSDDRQQMNQALMELYKKEKINPLGGCLPILVQIPVFIALYWVLVESVELRHAPFMLWIQDLSSRDPYFILPLLMGASMLVQMKLNPPPMDPIQKRVMQVLPFVFTGFFMLFPAGLVLYWLTNNILSIAQQWYILRQVEKSDTA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_DICNV
Sequence: MSGNSFGRAFVLTSFGESHGAAIGGIIDGCPARIAIDSKEIQKELDRRKPARSAYVSSRREADEIHLFSGIFEGQTTGTPIGFVIQNCDQRSDDYAPFKAQFRPSHADYTYQKKYGIRDYRGGGRASARETAVRVTGGAIAKAVLQQLCAIKVRAYLSQIGCHRLAFESWQAVSSNPFSCPNQHQLSVIAQYLEDIQRRGNSVGTEITVVAEQVPAGLGEPVFDRLDADIAKALMSINAVKAVAIGDGFTSANQYGSMFRDERTARDGFLSNHAGGILGGISSGQTIVASAVFKPTSSIPIPAKSVDQNGDDCIISVRGRHDPCVGLRAVPIVEAMVSLTLCDHLLRQRGQNGQR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LRGA_BACCZ
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDEKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_SYNJA
Sequence: MSAPPLPLLGQSLAALKDWAVEQGQPAYRGQQLHTWLYHKGIRSLQEVTVFPKAWREALQEYPVGRSQVVQRIESRDGTVKFLLQLADGELIETVGIPTARRLTVCVSSQVGCPMACNFCATGKMGYRRNLKLHEILDQVLTVQEDFGRRVSHVVFMGMGEPLLNRDTVVQAIRSLNQDIGIGQRHITLSTVGVPRQIPWLAQQDLQITLAVSLHAPNQELRQQLIPSAAHYPLDALIQDCRDYMLCSGRRISFEYTLLAGVNDLPIHARQLAHLLRQASQAGARLHVNLIPYNPIAEADYQRPHPTRVAEFVRLLEEHHVQVSVRQTRGLDSNAACGQLRGSFLRASPEPAPGRS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX3B_XENLA
Sequence: MYSMLDTDMKSPVQQSNALSGGPGTPGGKGNTSTPDQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVHMKDYPDYKYRPRRKTKTLLKKDKYSLPGNLLAPGINPVSGGVGQRIDTYPHMNGWTNGAYSLMQEQLGYGQHPAMNSSQMQQIQHRYDMGGLQYSPMMSSAQTYMNAAASTYSMSPAYNQQSSTVMSLASMGSVVKSEPSSPPPAITSHTQRACLGDLRDMISMYLPPGGDAGDHSSLQNSRLHSVHQHYQSAGGPGVNGTVPLTHI
What is the function of this protein?
Transcription factor with sequence-specific DNA binding activity.  Binds to the consensus sequence 5'-[AT][AT]CAA[AT]G-3', showing a preference for 5'-AACAAT-3' and 5'-AACAAAG-3'.  Inhibits beta-catenin-mediated dorsal axis specification by binding to sites within the promoter of the beta-catenin-regulated gene nodal5.  Acts maternally as a transcriptional repressor of nodal5 and nodal6 to restrict their expression to the vegetal hemisphere of early embryos and thus establish germ layer formation.  Acts at multiple points to inhibit nodal signaling, repressing the expression of the other mesoderm-inducing nodal genes nodal, nodal2 and nodal4, and also acting downstream to induce expression of genes including trim33/ectodermin, ema and coco, whose products repress nodal signaling (By similarity).
What are the official names of this protein?
Transcription factor Sox-3-B, Transcription factor Sox-11, xSox-11.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily cytoplasmic in early embryos. Nuclear localization becomes more pronounced as development proceeds (By similarity).
Protein: CPXCR_MOUSE
Sequence: MTSSNQGNDPSENTLKNAENETPNACEDEKEHPLPDTNISQVETNLSGMEPSSISSQEDMDFQTVQNSQPEAEMTQNDPPDEELIEDSLPLQIPIPKKLTIPRLILCRIIYLSIPQPQPQLHEKKTLSDKMMFHLGEVEMTENDCFHTPILDKMIHPCFLRWRVPFFTTNEISRMIIHLLCSRNFSQAECHQHNASVKQKYVAILDHQNIMNLQRNIVFGRPLRVYYYHPLFERLTQRKASKLYQHKNGNHLFVRPRFYMPQLQTQNTVQKNVFKHSWRAHHKLRLVIITDNNNWKYLCPICGCGFNNFYDFKHHSCSFSGN
What are the official names of this protein?
CPX chromosomal region candidate gene 1 protein homolog.
Protein: PYRF_METC4
Sequence: MPESADPRDRLIVALDLPDVEAAERLVARIGDAVTFYKIGYRLAYAGGLDFAARLAKSGKKTFLDLKLHDIGNTVEEGVRSASALGATFLTVHAYPQTMRAAVRGRGSGLKILAVTVLTSYDDADAAEAGYALPVADLVARRAEQAAEIGIDGIVCSAAEAGAVRHRIGPSGLIVTPGIRPAGAEAGDQKRVMTPGQARAAGIDHVVVGRPITGADDPRAVAQRIVAEMEDA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: S40A3_ORYSJ
Sequence: MSMSKLLSPPPTSPPGPALSRLPCRRVAPPPVLPFPFPLRRLTSRRVFATSCSSSDSEHAPSASSTALAGAGDDLSAGVTQEREGALPFVQLSSGIVLRTEEQSLLGDHAPAPAPASAASSFALLDELNGGCREDDHLGETPAYPAAMNALYAACLAGNATEQLWNFTWPAAVAVLHPASILPVAVLGFFTKLVVFAAGPLVGELISSLPRIPAYRSLAAIQTAAHLVSVATITYAFAVHRAAAASLLLRPWFAVLVASTAVDRLACVALGIIAERDFVVQLAGAGRPVALAKANATLSRVDLLCETVGASIFALLLSKNNPLTCIKLSCVISLCALPLLIFLCGEMNRLADGIFDHSENTTSHAEKTSSFSIRKTVEEAVATVRNGWSEYMRQPVLPASLAYVFVCFNVALAPGALMTTFLIHQGVRPSVIGAFGGSSGAVGILATFATARLVKELGILKAGAAGLIAQSALLGAAVVVYLTGAVSRRAGALFAFLGLIVASRAGHMAYSAIGLQVVQTGNPASKAKLIGATEIAVASLAELAMMAVAVVASDASHFGALAALSATAVTAAAGMYCRWLANPSDELRRIFPS
What is the function of this protein?
May be involved in iron transport and iron homeostasis.
What are the official names of this protein?
Solute carrier family 40 member 3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Protein: EIF3I_HUMAN
Sequence: MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815).  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632).  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, TGF-beta receptor-interacting protein 1, TRIP-1, eIF-3-beta, eIF3 p36.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
Protein: MUTS_BUCBP
Sequence: MSKIIMNKKNNDTPMIKQYLSLKLHYPNMFLFYRLGDFYELFFDDAKRISLMLDITLTKRGYSSQKEIPMAGIPYTSLNRYLSKLLKIGESAVICEQTHIIDKRTGLIERKISRVVTPGTVIDEEFLSETKNNLLGSVYYSKKRFGYATLDLCSGNFYISEYDTFESFISELQRTDPEELLIQEDFLYMNFFEKRKGIRLCKLNDFNIDSAYQQLKCHFKTKNLKSFGVYQNNLAISAAGCLLKYLKFIQYSLLPHVKSIKVRYDCNHIFMNSATRKNLEIINNISGKKEHTLLSILDNTATPMGGRLLRKWLSAPIKDIKIINKRHNIIKSLKTVYMSLSLLLKGIGDLERIISRIACRSASPKDFVSMRSALLQFSKIIFVLNSTKSKTLELISCKIKEYNSILILLRRSLKVCPSKTIKEGNVISENYNKDLDKWRKIANNASEYLQYFEVSERKRLHITSLKVNNNRVLGYYVQISKKDIKLAPNNYKKIQTLKHCVRYSTLELLDYENNVNNAKDKVLEIENYLYNELFDFIIPYIDSLKISVNTISELDVLNNLTERACVLNYVCPVISDEYGILLTDSRHPVVENLLKTPFVKNSINLSKSSNMLIITGPNMGGKSTYMRQIALIVIMAYIGSFVPAKYARIGLCDKIFTRIGSADNLAYGESTFMMEMIEMSSILRNSTSNSLVLIDELGRGTSMHDGLSLAWACIEYLAGKINAMTLFSTHYFELTKLKNYYSNIRNMYFDVLEHNNEIVFTYVIKNGFINKSYGLVVAALAKLPKCILLSAKKKLKEFYP
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SFR1_RAT
Sequence: MASAPSDIPENAFRLAKASGRCQSMMSQMKDETKCMGAVFSGYPTALWLEYEVSPQPMSGTLKERLKKARASSQPFCSVVKRIKVENEENDQTLSEPGESSKEENCSKAQESLENKDNEPEKESSEDKNTSESKSLDTGSSSVLQKDSTEKTIKQTLKEEKAKLTRQVQEKEDLLRRLKLVKMYRIKNDVTELEDLIKKWRRCGQRLLCELQSIMSEDEDEKLTLTELIDYYGIDDKLLHYNRTEEEFTGV
What is the function of this protein?
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.  Acts as a transcriptional modulator for ESR1.
What are the official names of this protein?
Swi5-dependent recombination DNA repair protein 1 homolog, Liver regeneration-related protein LRRGT00030, Meiosis protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFR1/MEI5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KPTA_PYRAB
Sequence: MGKAQSVRFKVSKLMAYILRHDPWSFNLQPDEEGFVDLEEFVNAIRRVYPWVTKEFILDIVERDEKERYEVKEGKIRARYGHSYPVILDHKEDKESKTLYHGTIRENLEGIMREGIKPMKRQFVHLSLNYEDAYNTGRRHGSNVVVLMIDADCLRKKGFKILKAGKKVRIVKYVPVDCIVGEL
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase (By similarity).
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: BIOF_METCA
Sequence: MTFDPASALAEIKARDAYRWRRIVESPQDTRVVIDGAPRVNFCSNDYLGLANHPAVREAFRRGVDRWGVGSGASHLVCGHSAAHHALEEELAEFTGRPRALLFSTGYMANLGVVSALAGRGDTVFEDRLNHASLLDGGLLSGARFRRYRHADARALEAALAESRAETRLVVTDGVFSMDGDLAPLPELARVARDGRAWLMVDDAHGLGVLGAEGRGTLEHFGLGAPEVPVLVGTLGKALGTFGAFVAGSESLIDYLIQRARTYVYTTALPPAVAEATRVSLRLVREEPERRERLRCNVRRFRAGAASLGFGLGDLPGPIQPLVIGANADALEASRRLGERGFLVSAIRPPTVQAGTARLRITLSAAHSNEQIDGLLEALADAVPQEA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: BICL2_XENLA
Sequence: MGWNGGLTSPSMEEHFYPFLIERRPSYMEEDEEEHEDEDLSLVLEKKDKDLLLAAELGKALLERNDQLMKAKDALEEELRETLETIEQEKHDMRLKMEVQESEWRAQVADLESDLAEARLQMQQLLSEQRECGRESASAAQELSEQNQRLVEQLAQASQVEQALNMELKSLREENRDLTISRGQFAPCLQSLRSENVLLLENKKEMESQTKQLQDENDNVQNQLISAKEGIFHLQRQKKDAELQVQQLQLEAQKLRDSQRTLQLQVKELQEELHMRDSQFSTHFSLHSEIQQSTAGQDHEMTTEAFPGLPCLPPSPYNLQKMGRNSVETQSITSDYMDTYLTEREGDLLRDSEEETIRLQDKVTMQHVELTTLQEEVQRLQDLLQQNNLDSIAKQAVLDRDEALMKKGELEQELARCQMEKESLNLQLLSTIQQKVMLSQELEAWQDDMQIVINQQLQSQKQQETQKVPETPQNSFMRRDSKQGRIFSFFKNI
What are the official names of this protein?
BICD family-like cargo adapter 2, Bicaudal D-related protein 2, BICD-related protein 2, BICDR-2, Coiled-coil domain-containing protein 64B.
What is the protein family that this protein belongs to?
Belongs to the BICDR family.