PharMolix/UniProtQA huggingface dataset:
Protein: NMB_BOVIN
Sequence: MTLRAVGVRLLGGLLLFALLAAGAAPLGWDLPESRSRASKIRVHPRGNLWATGHFMGKKSLEPPSPSLLGTAPHTSLRDQTPQLSHHLLRVLLQKQALGMSLSVPAPNTQHRRLLVQTLQK
What is the function of this protein?
Stimulates smooth muscle contraction (By similarity).  Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity).  Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity).  These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity).  Contributes to induction of acute itch, possibly through activation of the NMBR receptor on dorsal root ganglion neurons (By similarity).  Increases expression of NMBR and steroidogenic mediators STAR, CYP11A1 and HSD3B1 in Leydig cells, induces secretion of testosterone by Leydig cells and also promotes Leydig cell proliferation (By similarity).  Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (By similarity).  Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity).
What are the official names of this protein?
Neuromedin-B.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus//parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex.
Protein: VG70_ICHVA
Sequence: MDGYFKNITCEHEIICNDIRRAILDSAVEAEYSDYRLKSTMITFYSYYQHYLAIDPHCNTDVLNQTLGSNPVKLLLLTKLPCDDEMYDYISLTLGIPPHITGIWIRSWTPKTVYAAVCATEMCLAHMAPLKRIMEENPELFFEFYCVYNRIWKMNKFGEQTEQCCRGGRIMYNILLQCAQHGDPESIFYGLRGVIAFVRSTLGVHSRQLPVDIPNIDMSLLFKHFCV
What are the official names of this protein?
Uncharacterized protein ORF70.
Protein: THII_SHESA
Sequence: MKFIVKLYPEIMMKSKPVRMRFTKMLETNIRNVLKKVDEDAKVQRQWDRIWVKVPNDKPELAQAFGERLACIPGIAHVVQVDEYSFTSVDDIYQQVLPVYRDQIAGKTFCVRVKRTGSHDFNSIEVERYVGGGLNQFTDAIGVRLKNPEVTVNLEIEGDKLYMVTKRIEGLGGFPMATQEDVLSLISGGFDSGVSSYQFIKKGARTHYCFFNLGGAQHEIGVKQVAYHLWKTYGESHKVKFVSVPFEPVVAEILEKIDNGQMGVVLKRMMMRTAARIAERMGIQAIVTGESLGQVSSQTLTNLNVIDRCTDMLILRPLIAMDKQDIINECRRIGTEDFAKSMPEYCGVISQKPTVKAVLAKVEAEETKFSEDLIDRIVEQAVAIDIREIAEQMNTRITETETVVAIDTNEVVIDIRAPEEEENKPLEIEGVEIKRIPFFKLATQFADLDKQKTYLLYCERGVMSKLQALYLIEQGYHNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGYR1_AQUAE
Sequence: MIKAIFDTLCPNCGGEISAERLLKGLPCEKCLPEEVNREEVCQKLENGSFKEFCELLSELKDWEDFFKEILGTSPWSLQKSWARKVFLGRSFAMLAPTGVGKTTFGLSMASYLAKQGKKSYIILPTQLLVEQVSERIKTFGVDEDRLIVWGKLSEKKKKELKERIQKGDFDILITTSMFLYKNYEILPKDFSFIFVDDVDSFLKTAKNVDKVLYLLGFSEEDIHKAFELIRLKEKPNKSEEDWEEIKKRSEELREIAKKKKGVLAVSSATGNPRSNRIKLFRELLGFEVGKPSVLLRNIVETYEETQNLKETLLKRVKEFGKGGLVFVSSDYGREAVEEVKKFLESHGVKAVTYEEDLKLFEKGEAQVAIGISSFKNPLARGIDLPHVVRYAIFYGVPKIRVPLKVETSVSHLLWALLSLRPIILKDEKLKSEVKKVDTWIQRLRRYSFLSDDFVEERPDLKDRIENLRKEVQEFLLREDIVEKIKNSEELTLRLGEEGFELVVADVTGYLQASGRTSRMYAGGLTKGLSHVLVDDRRAFKNLEKKVRWFNQDINFKKIEEVDLKEVLREIDEDRKKVREILEGKVKAEQKEHVKPVLVVVESPNKARTIANFFGKPMGRKIGGIDVLEVMVGDLYIMITASLGHVFDLVKDKEFHGVIAKNGEYVPIYEVIEGKENIVKGLRELAQEVDTVLIGTDPDTEGEKIGWDLGALLSPYIPNVERIEFHEVTRKAIKHAVENPRDFNENLVKAQLVRRIADRWVGFEVSRIVQQAFDKHWLSGGRVQIPVLGWIIEREKLYRKKKHVVQITFKENGRWLRLGFEFQDKKEAKEFYENLKEIDVEVLEEREELKNPPPPFTTDTMLKEASDRYRISVPKLMQLAQELFEYGLITYHRTDSTRVSDVGIGVAKEWISEELGKELFYPRVWGEGGAHECIRPTKPLDVEDLRSMMLAGQLQNLTREHLLLYELIFKRFMASQMKPVKVKTKKVKVKALGREQELILTTEILEEGFNKVYPLELQPDLKGSVYVEDKKELKSVPMAYLYTQGSLVEEMKRRGIGRPSTYATIVSKLLERGYVIERHGFLIPTKLGKQVYEFLKSREKIMPFVSEEFTRKLEELMDKVEEGKEDYLQVLDELYKKVNEFEKANV
What is the function of this protein?
Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process.  It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue.  May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
What are the official names of this protein?
Reverse gyrase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
Protein: VP6_ROTA1
Sequence: MDVLYSLAKTLKDARARIVEGTLYTNVADIVQQVNQVINSINGSTFQTGGIGNLPIRNWTFDFGTLGTTLLNLDANYVENARTTIDYFIDFVDSVCVDEIVRESQRNGIAPQSDSLRQLSNAKYKRINYDNESEYIENWNLQNRRQRTGYLLHKPNILPYNNSFTLTRSQPAHDNVCGTIWLNNGSEIEIAGFDSECALNAPGNIQEFEHVVPMRRVLNNATVSLLPYAPRLTQRAVIPTADGLNTWLFNPIILRPNNVQVEFLLNGQVITNYQARYGILAARNFDSIRISFQLVRPPNMTPGVAALFPVAAPFPNHATVGLTLKIESASCESVLSDANEPYLSIVTGLRQEYAIPVGPVFPAGMNWTELLNNYSASREDNLQRIFTAASIRSMIIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RPO5_METMA
Sequence: MTKFSLLDHEAVPKHEIMSEGELKSVLSKYFIEKEQLPKIKVQDPVCKEIGAVVGDVVKITRKSQTAGEADYYRLVIE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_OENOB
Sequence: MSLIASIYAREVLDSRGNPTVEAEVYSEDGFFGRGIVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVANVNGAIAEALIGKFDVADQRGIDLAMIALDGTPNKGKLGANAILSVSIATARAAAEEAGLPLYQYLGGPNSYVLPTPMMNVINGGVHSDNKVDFQEFMIMPVGAKTVKEAIRMGSETFHNLKKLLEADGKNTSVGDEGGFAPDFANNEEPLQYLVKAIQAAGYKPGKDIALATDVAASELYDADTKKYKLKWSTGEEFTAPEFEKYIEGLVAKYPIVSVEDPLDENEWDDWVEVTKELGKKVQIVGDDFFVTNTDYLKRGIEMGAANAILIKLNQIGTLTETFEAIEMAKEAGYTAIVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEDELNQGEPEGVSIYKGINSFYNLNADAKKEIQSHQG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y785_CLOBK
Sequence: MARGGFPNMGGANMNNLMKQAQKLQQDMEKMQGEMEKKEFSATVGGGAVTAVANGKKQIVDIKIEPEVVDEDDIEMLEDLIMSACNEALKKAEEDTSSEVKRLTGGMNLPGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CLD_0785.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL15_MACFA
Sequence: MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_WOLPM
Sequence: MKGLYIKTYGCQMNVYDSVLMENVIKPLGFNVVSDAGKADLVILNTCHIREKAAEKLYSELGKIHSLRKEMTIVVAGCVAQAEGEEVFRRAPFVDIVVGPQSIATLPELIVKASRSKGHVINTDFPEVAKFDKLPDECYGNSQGSSAFLAIQEGCDKFCTFCVVPYTRGAEYSRPVNEIFREALKLVANGANEINLLGQNVNAYHGECEGEVWDLGKLISHIAKIEKLERIRYTTSHPRDMHESLYLAHAEEPKLMPFVHLPVQSGSNKILHAMNRKHTAEEYLEIIDRFRKLKPEIEFSSDFIVGFPGETEKDFEETMKLVEKVRYAQAYSFKYSPRPGTPGAERKDQVPEEVKTERLLRLQKLISKQQLEFNQSMVGKTIPVLFSDKKGKHQNQIIGKSPYMQSVCIDDSEDKYRDKIVNVKVLEARQSSLLGCAFH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_THET8
Sequence: MRALAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGVDRDGGFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPYADRLVNPLEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPGGEARILGIPSDPIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVILDPKA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_RHOE4
Sequence: MRHYELMVILDPSLDERTVAPSLDTFLNVVRQHGGTIDKVDVWGKRRLAYEILKHAEGIYAVIDINATPATVAELDRQLGLNESVLRTKVLRHNK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DNAK_HALMT
Sequence: MASNKILGIDLGTTNSAFAVMEGGDPEIIVNAEGDRTTPSVVAFTDDGERLVGKPAKNQAIQNPEHTIRSIKRHMGDDGYTVDIEGEEYTPEQISAMILQKIKRDAEDYLGDEVEKAVITVPAYFNDKQRQATKDAGEIAGLEVERIVNEPTAASMAYGLDDESNQTVLVYDLGGGTFDVSVLDLGGGVYEVVATNGDNELGGDDWDEAIIDWLATEFKNDHGIDLREDRQALQRLKDAAEEAKIELSSRKETTINLPFITATDSGPVHLEYDLTRAKFESLTKDLIDRTVEPTEQALEDAGYGKDDIDDVILVGGSTRMPQVLDKVEEILGSEPKKSVNPDEAVALGAAIQGGVLGGEVDDIVLLDVTPLSLGIEVKGGLFERLIEKNTTIPTEESKIFTTAADNQTTVQVRVFQGEREMAEDNELLGEFTLSGIPPAPAGTPQIEVGFNIDENGIVNVSAEDKGSGNAESITIEGGAGLSDDEIDRMQREAEQHAEEDKERRRAVEARNEAEGAVQRAETLLEENEENVDDELRADIEAAIEDVEAVLEDDDASTDELEDVTEDLSKELQEIGKRMYQQQAQAQAGGPGGAGGPGGADGPGADADPEDFVDADADFDDEDDDE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NTPP_CAMJE
Sequence: MLILASSSISRANLLKTAKIDFRQVSFDYDENLNKNISPFLYVQKIVLEKERQFLSTLGKDFQNQNLLFADSIVCIDEKILTKAKDKKEAYEMLALQNGKYASILSAFLLVKPEKRVFSLSKTTLYFKNFDENALRDYVENDLYKGKAGCIMCEGFHQNFITQQVGNLSTALGLDIQTLKAYL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGN4_HUMAN
Sequence: MPKRKAKGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPRPKKASAKKGEKLPKGRKGKADAGKDGNNPAKNRDASTLQSQKAEGTGDAK
What are the official names of this protein?
High mobility group nucleosome-binding domain-containing protein 4, Non-histone chromosomal protein HMG-17-like 3, Non-histone chromosomal protein.
What is the protein family that this protein belongs to?
Belongs to the HMGN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2B_GLOHA
Sequence: NLLQFRKMIKKMTGKEVVWYAFYGCYCGGGGK
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAO6_ORYSJ
Sequence: MTKPTTMAIFLVLALSIAQLLPSLVAGTGRPRVIIVGAGISGISAGKRIWEAGIADVLILEATDRIGGRMHKQSFAGVNVEIGANWVEGVNGEKKNPIWPIVNSTLKLRSFRSDFDSLAQNVYKDGGLCDEAYVQKRMDRADEVDKSGENLSATLHPSGRDDMSILSMQRLNDHLPNGPSSPVDMAVDYFTYDYEFAEPPRVTSLQNTVPLPTFTDFGDDTYFVADQRGYESVVHHLAGQYLNADKSGNIADARLKLNKVVREISYSSTGVTVKTEDNSTYQADYVMVSASLGVLQSDLIQFKPQLPSWKILAIYQFDMAVYTKIFVKFPKKFWPEGAGREFFLYASTRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQPDSQTKAEIMEVVRCMFPDEDVPDATDILVPRWWSDRFFRGSFSNWPIGVSRYEYDQLRAPVGRVYFTGEHTSERYNGYVHGAYLAGIDSAEILINCAQKKMCKYNVGGKHG
What is the function of this protein?
Flavoenzyme involved in polyamine back-conversion (By similarity).  Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and spermidine (By similarity).
What are the official names of this protein?
Polyamine oxidase 6, OsPAO6, Polyamine oxidase B.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: TIG_CLOBM
Sequence: MNVKVENIEKNVVKLEITVDSEKFNEAVKKSFKKNAKRFNVPGFRKGKAPLNIIKKYYGEGVLFEDAINFCCEDTYPKAIEENNIKPVDYPQIDVVQIGEGKDFIYTAEVTTVPEVKLGEYKGVEVKKVSYEVEDEAVENELKSMQEKNARVFLKEEGEIEKGNIAIIDFKGYVDGKAFEGGEAKDYEIEIGSGTFIGDFEDQLVGLKKDESKEVNVSFPEEYGREDLNGKPATFEVTIKDIKVKELPALDDEFAKEVSEFDTLEELKSDIKDRMKKELSEKAKAEYEEAVVEAVGANAEIEIPKVMIEKEIENMVRDLEMRLKYQGLDLKSYYEFTNSSEEKVKEYMRETAEKRVKTDLIMQEIAKVEDIKATEEELKEKAMEVAKQYGQKDVEKTAELIANAQKSYLEIDIVNGKVLDLLVENSKEIA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RPOA_EREDI
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPLFTFKKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DECO_LAMBD
Sequence: MTSKETFTHYQPQGNSDPAHTATAPGGLSAKAPAMTPLMLDTSSRKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAFAGTAISIV
What is the function of this protein?
Stabilizes the expansion of the capsid head shell after genome packaging.  The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases.  415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell.
What are the official names of this protein?
Capsid decoration protein, Auxiliary protein D, Gene product D, gpD, Major capsid protein D.
What is the protein family that this protein belongs to?
Belongs to the lambda phage gpD family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: LFTR_BRUMB
Sequence: MTAEAPPDDDIIEPEMLLRAYATGIFPMAEEADDPEVFWVRPEKRGVIPLDGFHIPRSLQKTIRQGIFEIRLDSNFAGVIEGCASGTGERARTWINEPIRRAYAKLFEIGHCHTVEAWYEGKLAGGLYGVTLGRAFFGESMFTRKRDASKVCLAYLVQHLSRQGFVLLDTQFTTPHLERFGALEVPRKEYEEMLERALEGIARF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPDD_ECOLI
Sequence: MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN
What is the function of this protein?
Major component of the type IV pilus (T4P) that plays a role in cell adhesion and motility.  Not produced when grown under standard laboratory conditions.
What are the official names of this protein?
Prepilin peptidase-dependent protein D.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: ACCA_STAA3
Sequence: MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_BORA1
Sequence: MSASSIARTVYIVSDSTGITAETFSQSVLSQFDQVDFKPIRLPFIDTLQKAEETAERINKNAADTGVPPIVFSTLVNPEILARVRQANGVFLDLFGTFVSHIEQALGLKSSPSIGRSHMQADSEKYRNRIDAINFSLAHDDGQFVNQLDQADVILVGVSRCGKTPTSLYLAMQYAIKAANFPLTPDDFERSSLPKTIAPYRDKLFGLSIQPERLSEVRNERRPNSRYATIEQCRYEVAEAERMMRRAGISWLSTTTKSIEEIATTVLQEVGLGR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: SECB_XANC8
Sequence: MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQRLNDNAFEVVLAVTLTCTAGGKTAYVAEVQQAGVFGLVGLEPQAIDVLLGTQCPNILFPYVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRSQGETSLADSEPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX9_DANRE
Sequence: MAESNQNTDGAVEEGEDENTGDSNLQMELSAFRAKWMSELQPSSGGQRSFSRNAELRRRQETAKEEKARELFLKAVEEEQNGAVYEAIKYYKSAMQLVPDIEFKINYSRTPDPERGGSYLESSENNREIDDLLTYFQHQLTLGNDAMKLCEHETETSQVHISALPFEVLMYIFRWVVSCDLDLRALEQLSLVCRGFYICARDPEIWRSACLRVWGRSCTKMLPYSSWREMFLERPRVRFDGVYISKTSYIRQGEESLDGFYRAWHQVEYYRYLRFFPDGQVMMLTTPEDPLVTVPRLRSKNSRMDSIMFGHYRLSQDTDNQTKVYVVVSKRKEEKVSEYQRSRFCRRNPVPEAERSFHVGLQLSSGGRQRFNKLVWIHHSCHITYRSTGETVVTAFDVDKMYTPLFFARVKSYTAFSERPL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and acts as a regulator of mTOR signaling.
What are the official names of this protein?
F-box only protein 9.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_HELPY
Sequence: MLKELRQKRPLVHNITNYVAAQFVANGLLALGASPLMSDAIDEMRDLAKISDALAINIGTLNDRAILCAKEAIKHYKALNKPIVLDPVGCSASALRHDTSLELLKSGGISALRGNAAELGSLVGISCESKGLDSNDAATPVEIIKLAAQKYSVIAVMTGKTDYVSDGKKVLSITGGSEYLALITGAGCLHAAACASFLSLKKDPLDSMAQLCALYKQAAFNAQKKVLENNGSNGSFLFYFLDALSLPIELENSLIKEEW
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.