PharMolix/UniProtQA huggingface dataset:
Protein: G1PDH_METAC
Sequence: MKLTINKNSAKWMQLPRDVLVGHGVLEEIGDVCRDLKLKGNALIVTGNTTRDVAGKRVSTLLENAGSSTEMVLTCRATMEEVDKIMQKASETGATFLLGIGSGRSIDLAKLASTRLEIPFISVPTAASHDGIASSRASIIDNGKNASVQAQAPIAVVADTEIISAAPFRFLVAGCGDIISNYTAVLDWELASRLRNEYFGEYAAALSRMAARVVIENADSIKPEHETSARLVVKALVSNGVAMSIAGSSRPASGSEHMFSHALDRIAPKPALHGEQCGVGTIMMMYLHGGNWQEIRDALKKIGAPTNAEELGIEDRYIVEALLHAHSIRPDRYTILGNGLTPSAAEKVARITKVIS
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM13_ASPFU
Sequence: MAIWGSSSSNTASSGEADIKTHLMNQVRQEAAVTNARNLIGKVNEHCFEACIPNPGTSLSSAEHTCLSQCMEKYISFWNAVSRGYIARLANERKAYGGGALDASFVQSGESSL
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: YQJY_BACSU
Sequence: MDIRTITSSDYEMVTSVLNEWWGGRQLKEKLPRLFFEHFQDTSFITSEHNSMTGFLIGFQSQSDPETAYIHFSGVHPDFRKMQIGKQLYDVFIETVKQRGCTRVKCVTSPVNKVSIAYHTKLGFDIEKGTKTVNGISVFANYDGPGQDRVLFVKNI
What are the official names of this protein?
Uncharacterized protein YqjY.
Protein: S39AC_HUMAN
Sequence: MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
What is the function of this protein?
Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane.  The transport activity is temperature dependent.  May play a role in neurulation and neurite extension.  May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis.
What are the official names of this protein?
Zinc transporter ZIP12, LIV-1 subfamily of ZIP zinc transporter 8, LZT-Hs8, Solute carrier family 39 member 12, Zrt- and Irt-like protein 12, ZIP-12.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BCAR3_BOVIN
Sequence: MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAERILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF
What is the function of this protein?
Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity).  Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity).  Promotes insulin-mediated membrane ruffling (By similarity).  In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1.  Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity.  May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity).  Regulates EGF-induced DNA synthesis (By similarity).  Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling.  Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA.  Positively regulates integrin-induced tyrosine phosphorylation of BCAR1.  Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity).  However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity).
What are the official names of this protein?
Breast cancer anti-estrogen resistance protein 3 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Localization to focal adhesions depends on interaction with PTPRA.
Protein: ADH_SCAAL
Sequence: MCIAGKNIIFVAGLGGIGLDTNREIVKSGPKNLVILDRIENPAAIAELQAINPNVTVSFYPYDVTVALAESVKLLKTIFAKLKTVDLLVNGAGILDDHQIERTIAVNFTGTVNTTTAIMEFWDKRKGGPGGVIANICSVTGFNSIYQVPVYSASKAAALSFTSSLARLAPITGVTVYSINPGITDTTLVHKFNSWLDVEPRVAEKLLAFPTQTSLACAKNFVRAIEANKNGAIWKLDLNRLDEIEWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TRPG_METTM
Sequence: MNKLILIIDNYDSFTHNLYQMAGEIMMEMDSADIMVVRNDEVDIDYVRGLDPERIIISPGPGNPIKREDFGICSEVIGEFTDRPILGVCLGHQGIFHYFGGVVGYGEPVHGKISEVFHDGSELFRGVPNPFRATRYHSLRCECSGVPEDILVSASAPDGTIMAIRHRQYPVYGLQFHPESAGTPHGRDILENFLRM
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: TPS1_BOTFB
Sequence: MPSVAGEEPKASSRLLLVSNRLPITIKRTEDGQYDFTGSSGGLVTGLSGLAKTTTFQWYGWPGLEVPDAEAKPLVKRLKDEHGAHPVFVDDELADKHYNGFSNSILWPLFHYHPGEITFDESQWMAYKEVNRLFAKTIAKDVQDGDLIWVHDYHLMLLPEMLRDEIGTSKKNVKIGFFLHTPFPSSEIYRILPVRESLLLSVLHCDLIGFHTYDYARHFLSSCSRILETQTTPNGVEFRGKYVTVAAFPIGIDPEKFIETLKKPKVEERIAQLERKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGRFGTVEFMPIHFLHQSVNFDELTALYAVSDACLVSSTRDGMNLVSYEYIATQRKRHGVMILSEFTGAAQSLNGALIVNPWNTEELADAIHDAVTMSPEQREINFKKLEKYVFKYTSSWWGESFVSELQRISEHAAKKSNSKGTVDKMPDLVEGVQQFNLGEQREEGRLEPGEFDD
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process (PubMed:16946258).  The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination (PubMed:16946258).  Trehalose also serves as a protectant for cell integrity during stress (PubMed:16946258).
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: SHC1_PONAB
Sequence: MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLRDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARSTAPSAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAVNGSAPRDLFDMRPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLIGYHMDNHLPIISAGSELCLQQPVERKL
What is the function of this protein?
Signaling adapter that couples activated growth factor receptors to signaling pathways.  Participates in a signaling cascade initiated by activated KIT and KITLG/SCF.  Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).
What are the official names of this protein?
SHC-transforming protein 1, Src homology 2 domain-containing-transforming protein C1, SH2 domain protein C1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_HERA2
Sequence: MELNDLQQTRYGKLQALQAAGIEPYPARVPQRTHTLTAVREQFSALVEANATVTIMGRLRQRRVMGKSAFAHLNDDHGAFQIFLSKADVGDEPFKHFVDLTDLGDIIAVTGTLFTTKMGEPSVHVTSWTMLSKAITPPPDKREGQFSDQEARQRQRYVDLSANPEVREIFRIRARLITAMRRYLDERGFLEVETPVLQGIYGGAAARPFTTHHNQLHQDLYLRIATELYLKRLIVGGFDGVYEIGKNFRNEGVDRTHNPEFTMIEVYQAYGDYESIMQLTEGMIRFAAEQIFNSTSIEYQGHQIELGGSWQRLTMRDAIFEKTGVDIRECREFDTLWEAIGEAGLKIERKPTWAKQVDELFSEFVEPELIQPTFITEYPQPLSPLAKRKADDPQFVERFELFMLGAEIANAFSELNDPFDQEQRFLEQGRDYAAGDDEAMQMDEDYLEALKVGMPPTGGLGIGIDRLCLLFTNQTTIREVIFFPHLRKQGEE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_PROMA
Sequence: MSNSQLKIKTKALPNSRIAIEFEVPAQQCKTSFEDALTTLCKSANLPGFRKGKVPKSVILQQIGSKRIQASALEKLLEKIWKQALKEESIEPLCEPELAGGFEPLLENFNPEQTLSVTLETDVAPIPKLKTTKGLTTEAEPITFDESKVDELIEESRKQLATVIPVENRPANHSDIAILTFKGTFADDGSEIEGGSGESMEIDLEEGRMIPGFIEGIVGMKINETKTIDCQFPKDYQDEKAKGRKAKFDIQLQDLKTRELPKLDDDFAKQASDKNSLKELRNELTNRLKSDAKNRNKKNRQESLLEALVKELEVDLPKTLIDEEVRNLIEQTARNFAEQGMDIKSTFTQDLVSSLMESSRPEAEINLKKNLALNALAEAENIKVDSQALEEKIKEVNIELANQKNIDQKKLRQVVQNDLLQEKLFDWLEANNTILEKKPKKALNEKVKSSKPKNTQKKTDKTKKDSP
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EFTU_RICPR
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITIILAKTGGAKATAYDQIDAAPEEKERGITISTAHVEYETQNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPAMVVFLNKVDMVDDPDLLELVEMEVRELLSKYGFPGNEIPIIKGSALQALEGKPEGEKAINELMNAVDSYIPQPIRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEIEIVGLKNTQKTTCTGVEMFRKLLDEGQSGDNVGILLRGTKREEVERGQVLAKPGSIKPHDKFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPSDKQMVMPGDNATFSVELIKPIAMQEGLKFSIREGGRTVGAGIVTKINN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYC_ENCCU
Sequence: MTDAREKGFWTGPLEMADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRVGERYYGGTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRIMGLDLPSGGHLTHGYKTKTRKISASSVYFDSRPYTVGSNGLIDYEGLEKTFTDFLPHILICGYSAYSRDIDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKGLRGPRGALIFYRRAVTKNGETVDLDARINFAVFPMLQGGPHNHTIAGIASALLHAGTPEFAEYTRRVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCDALGISLNRNAIVGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDIIGGVVKLCREMTGGRKMSKADLHRVTSDARVMGSEQVLVLRRRVCALAEAYPIYE
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARX_ECO57
Sequence: MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE
What is the function of this protein?
Acts as a sensor for nitrate/nitrite and transduces signal of nitrate availability to the NarL protein and of both nitrate/nitrite to the NarP protein.  NarX probably activates NarL and NarP by phosphorylation in the presence of nitrate.  NarX also plays a negative role in controlling NarL activity, probably through dephosphorylation in the absence of nitrate (By similarity).
What are the official names of this protein?
Nitrate/nitrite sensor protein NarX.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECF_CERS4
Sequence: MAFRLKLCPEKTNIDFFWAAPVTFGFSVFLMAASLVAWLTLGLNFGIDFRGGTTIRTESTQAVDVAAYRAALEGQDLGDISITEVFDPGFRADQHVAMVRIGAQDATQSITPEQIGQVEEALKTVDPSITFPSVESVGPKVSGELIRSAILAVAAACAGIAVYIWLRFEWQFALGSVAALIHDVLVTIGVFALFQIKFDLTTVAALLTVLGYSINDTVVVFDRLRENLVKYKTMPLRDVMNLSVNETLSRTIMTLMTTLIALVSLLVFGGDVIRGFVFAITFGVVIGTYSSVYMAKNIVLYLGVDRGGPKKDSKAGTQFANIDA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGD_SALTI
Sequence: MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVFTNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAVGKVVA
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Acetylornithine/succinyldiaminopimelate aminotransferase, ACOAT, DapATase, Succinyldiaminopimelate transferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM9_XENTR
Sequence: MYLSPEQVALVGQVFESFVLEHHQKEIAQILTEKYEDAHYSLVVNAMTLFEANMEIGEYFNAFPNEVLPIFDNALRRAAMSFLQSCSEKQTLVMKQNFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRTSLVKVLEYEQDFMCNKCKHVVTVKADFEQYYTFKPPITCSNEEGCNSSKFTCLSDSSTPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGVVMQRWKPLYIDTRCDLEIVLKANYIAVNNEQPCGVVINEEVRKEYEGFWEKYRNSPLEGRNEILASLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDSGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFILESKGCPRKSDKLWSMEKMKTYFCLIKNLQPKMSQDANVILVRYYQLQRQSSCRNAARTTIRLLESLIRLAEAHARLMYRDVVTTEDAITVVSIMESSMQGGALLGGVNALHTSFPENPREQYRMQCELLLERLGLQKLLDKELQRLDRQQNEDSLESDHGESASNISCNLVGHKVHSDSAMEETCSTNETFSSPDATRKTIPDILDMTKSDDTISKGTITPAEQNRAIRTQSKSSSKHNTQSLAGGHLSENHLTRCSDKSLGWFDSLQSVQMSPISKLGEGCTAEKLQPAVLPVLAEGSCHPDKEVVDLVGNKSEVLQKSGSSPVGTERHLSNRIVTEHVSKKWQNLNKNSLCGKTGSNMTSLQSENSGSHTVCSSGPLHSTPGAPWKRKKIIAQVEKETKAELLDPDTQARLVQLARFSFKQHSKLVHLPGGKTDIASIAQNHEDQPDQKLTPSDRLNKLDRILNNVDKASNSVKGLKQQDTLAQENPPKQTVLAQQSNSISNAATACVHEKKLNEGSDSRKVSSSTLAKLARFSFSPPPENKALEASKETLISSRAAAPSSKRKCFQLEPSSDKTTMSSKFLFSTDLDDDELDVDWEVEIKRNKRTAT
What is the function of this protein?
Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis.  The MCM8-MCM9 complex probably acts as a hexameric helicase required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.  In eggs, required for MCM2-7 loading onto chromatin during DNA replication.  Probably not required for DNA replication in other cells (By similarity).
What are the official names of this protein?
DNA helicase MCM9, Minichromosome maintenance 9.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci and colocalizes with rad51.
Protein: GLGB_BORBR
Sequence: MMRDSPSIQGTLDAATQHALLAGRHADPFSVLGPHQAGAHTVVRVLAPGARTVMAVLPGGQRTPLLPMQPGLFENTVPGLQPGAPAAYRLCIEWEGGIQHTADPYAFGPVLDAAQLDHCAAGGWRYLAGLLGAHAASVDGCAGTRFALWAPNARRVAVVGDFNGWDGRRHAMRLRYPAGVWELFLPDVGPGARYKFQVLGADGHTVLKADPLARQAEAPPATASIVPDERPFAWTDEAWMEQRAARQRCDAPISIYEVHAGSWFDDAGAPRWQSLAARLPEYARSLGFTHIELLPVMAHPFGGSWGYQPLGLFAPAAAHGAPADFAHFVDRCHEAGLGVILDWVPAHFPDDAHGLARLDGTPLYEHADPREGRHPDWNTLIYNYGRREVRAFLIASAIHWLRHYHVDGLRVDAVASMLYRDYSRPAGQWIPNRHGGRENLEAIDFLRELNAAVGVQCPGAITVAEESTAWPGVTAPVANGGLGFDYKWNMGWMHDTLRYMRRDPIHRRHHHHDLSFGMVYAYAERFVLPLSHDEVVHGKGSLLGKMPGERAAQLAQLRLYYAFMWAHPGKKLLFMGGEFGQQGEWNHDAMLQWSLLDDPAHRGLQRLIADLNHVYATLPELHCRDADPSGFAWIVGDDADNSVLAFARVDASHCLVAVCNFTPVPRPGYRFGVPHAGDWRVRVDTGATRYGGAGGGPPICLRSEPIPAHGHPQSLVLDLPGFTALYLRHSE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: GSH1_BORPA
Sequence: MTDTAAQRHHRLQAHADLLTQTLRGIEKEGLRVDHQGVLARTAHPAGLGAALTNAHVTTDYSEALLELITGTHTEVDSLLGELRDTHRYVYGVLEGEYIWNQSMPATLPPEADIPIAWYGTSNTGMLKHVYRRGLAERYGKTMQCIAGVHYNFSLPDALWDVLVPDAPTPQARRSRGYISLIRNFTRYSWLLMYLFGSAPALAREFMRGRDHLLETLDPSTLYLPYATSLRMSDLGYQNKAQSRLKLCYNDLDTFLGRLYEAVTEPWPAYQAIGTRRDGQWIQLNTNVLQIENEYYSSIRPKRATGRCERPITALAERGVQYVEVRCLDIDPLTPEGISAETARFVDAFLLFCATSDSPFFPDNGYCQRSADNFAVVVKEGRKPGLMLDREGQAVSVPQWGHELLDQIAPYAALYDQALGGDAYAAALAAQRAKLDQPDLTPSARVLAALREGNVSFHDYSLDLSRRHADALRAQPLPAERTQAYAEAARQSVAEQLRLEQSDAVDFDTYVAHYHAALKNPLPSTAS
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: Y1177_PECAS
Sequence: MFGKGGIGNLMKQAQQMQEKMQQMQEEVANLEVTGESGAGLVKITINGAHNCRRVEIDPSLMEDDKEMLEDLIAAAFNDAARRIAETQKEKMATVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein ECA1177.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NSR_LACLL
Sequence: MKIGKRILLGLVAVCALFLGIIYLWGYKFNIYLVPPSPQKYVRVALKNMDELGLFTDSKEWVETKKKTIEETSNAKNYAETIPFLQKAIKVAGGKHSFIEHEEDISKRSMTKYIKPKAEIEGNTLILTIPEFTGNDSQASDYANFLESSLHKNNYNGVIVDLRGNRGGDLSPMVLGLSPLLPDGTLFTYVDKSSHSKPVELQNGEINSGGSSTKISDNKKIKKAPIAVLIDNNTGSSGELTALCFEGIPNVKFLGSDSAGYTSANQTVYLYDGSTLQITSAFVKDRTNNIYKNFPISPDIQTNNAKSSAIEWIKSQIK
What are the official names of this protein?
Nisin-resistance protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MTLD_VIBCM
Sequence: MKKNAVHFGAGNIGRGFIGKLLADADIAVTFADVNEPLVDQLSHQQEYKVKVVGSECKMETVSHVTAVNSASEALIERIIKTDLVTTAVGPTVLDIIAKTIAKGLSARFAAGNTQPLNIIACENMVRGTTHLKQQVYQFLTTEEQQQADALVGFVDSAVDRIVPPLQAANDDPLEVTVESFSEWIVDEQQFKGEIPQIEGMEKTDNLMAFVERKLFTLNTGHCVTAYLGCLKGHRTIREAIEDPCIHAQVKQAMQESGEVLIRRYGFDRALHSAYIEKILSRFANPYLVDEVDRVGRQPLRKLSANDRLIKPLLGTIEYGLPNGMLLKGIAAALKYRNSSDPQAVELQQSIEKEGVRSTLARYTGLAAESVEAQQIEALYQQMD
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RSMH_VARPS
Sequence: MNTPWTHTTVLLNEAVEALLSGSTAATGTYVDATFGRGGHARAILARLAPEGRLIAFDKDAEAVAEAARISDARFSIRHQGFRSLGELPDASVAGVLMDLGVSSPQIDNPVRGFSFRFDGPLDMRMDTTRGESVADWLATAELQQIAEVIRDYGEERFAVQIAKAIVARRQERGAISTTSELAELVAGTVKTREPGQNPATRTFQAFRIFINAELEELQQALEASLSVLQPGGRLAVISFHSLEDRIVKQFIARHSKEVYDRRAPFAAPKAMKLRALERIKPSDAEVHGNPRSRSAILRVAERTQEV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.