PharMolix/UniProtQA huggingface dataset:
Protein: GCH1_SHIBS
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ENTE_ECO57
Sequence: MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGEHNLQDAINHPADGFTATPSPADEVVYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQINVTALVPPAVSLWLQALTEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASA
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms.  EntE proccesses via a two-step adenylation-ligation reaction (bi-uni-uni-bi ping-pong mechanism).  First, it catalyzes the activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via a reversible ATP-dependent pyrophosphate exchange reactions to yield the acyladenylate intermediate 2,3-dihydroxybenzoyl-AMP.  It can also transfer AMP to salicylate, 2,4-dihydroxybenzoate, gentisate and 2,3,4-trihydroxybenzoate.  In the second step, DHB is transferred from 2,3-dihydroxybenzoyl-AMP onto the phosphopantetheinylated EntB (holo-EntB) to form DHB-holo-EntB.  Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine.
What are the official names of this protein?
Enterobactin synthase component E, 2,3-dihydroxybenzoate-AMP liase, DHB-AMP ligase, 2,3-dihydroxybenzoate-AMP synthase, Dihydroxybenzoic acid-activating enzyme, Enterochelin synthase E.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. EntE subfamily.
What are the subcellular locations of this protein?
Membrane.
Protein: COQ4_COCIM
Sequence: MAIAKSVRARAVGLRSLRVLCAQRSVAREFSVLNRPQPNYPGHIPLTPIERGALAIGSAVGSLLNPRRGDLIATVGETTATPFFIYRLRDAMLADPTGRRILRDRPRITSQTLSLPYLRSLPKNTVGYTYATWLDREGVSPDTRSSVQYIDDEECAYVMQRYRECHDFYHAVTGLPIVVEGEIALKAFEFMNTLIPMTGLSVFAAIRLKPEEKQRFWSIHLPWAIRSGLASKELINVYWEEQLERDVNELREELNIEKPPDLRDIRKKVREQKKAAKEAVIKS
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GSA1_STAA8
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGNDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BARHE
Sequence: MRVYYDRDANVNLIKEKKVAIVGYGSQGRAHALNLRDFGVKNVKIALRSESATVKKAVADGFEVVCVAEAAKWADLIMMATPDELQADIYKEHIHDHLRDGAVIAFAHGLSIHFGLIEPKKTVDVVMIAPKGPGHTVRNEYQNGCGVPCLIAVAQDASGHAHNVALSYACGLGGGRAGVIETTFKEECETDLFGEQAVLCGGLVELIRAGYETLTEAGYAPEMAYFECLHEVKLIVDLMYEGGIANMNYSISNTAEWGEYMSGPRVITDETRAEMKRILKDIQTGKFTSNWIQEYKAGAAHFKGMRRLNDSHPIEEVGKKLRSMMPWIKANALVDKERN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: Y795_METJA
Sequence: MKRLKNLFIIFIFLFLLSQVSAYITFKNIDYNAQYLEPSKTYDLYITIESDKEINNTVVYIEPTNQISKENIEIIRGKQWIGHLFPYEYGVAHLIIKINPNAPNYDYKITGYCNYTKGNQQYSENRIFTLPVRGKANLVIETTNNILKVGNNQILLLLTNKGTGTAENIKIEFQNSNNLMVLGDNTFTISALGSKTSTYIPLTIFAKKEGVYSINYKISYKNPYNLLELTQKSETIEGDSKTETLTYQNKNIVEETGILTFNVFPNELISINIKNPTITVGKIENLTISIKNNYKDSLFVVQISKYFIGNNQKSIFIKKGETKNLTFQIKVDKEGVTSIPIVIYFDNNQIEKNLTINVVGKADLVLSGIDIESSFNEIKITGDIDNIGTGKAKSVLISIEKTKNIIPKKPYENYFVGTLNPDDYGSFELHCQINGNVNEIPLKISYRDEDNNLITIYKTVKISKEVVSLKTNNNGGINYLVVGIAILFCVGVVYLIYRGFVKKK
What are the official names of this protein?
Uncharacterized protein MJ0795.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1506 and MJ1561.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PARE_STAAN
Sequence: MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGSIYHQSFKNGGSPSSGLVKKGKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: FABH_STAA8
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPNE_ECOLI
Sequence: MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHQDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFLLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCH
What is the function of this protein?
Upon expression has no effect on RecA-independent DNA recombination, cell viability or DNA damage (PubMed:28096446).
What are the official names of this protein?
Inactive recombination-promoting nuclease-like protein RpnE.
What is the protein family that this protein belongs to?
Belongs to the Rpn/YhgA-like nuclease family.
Protein: WTR13_ARATH
Sequence: MEEVKKRDCMEKARPFISMVVLQVGLAGMDILSKAVLNKGMSNYVLVVYRHAVATIVMAPFAFYFDKKVRPKMTLMIFFKISLLGLLEPVIDQNLYYLGMKYTTATFATAMYNVLPAITFVLAYIFGLERVKLRCIRSTGKVVGTLATVGGAMIMTLVKGPVLDLFWTKGVSAHNTAGTDIHSAIKGAVLVTIGCFSYACFMILQAITLRTYPAELSLTAWICLMGTIEGTAVALVMEKGNPSAWAIGWDTKLLTATYSGIVCSALAYYVGGVVMKTRGPVFVTAFSPLCMIIVAIMSTIIFAEQMYLGRVLGAVVICAGLYLVIWGKGKDYKYNSTLQLDDESAQPKLELSGNGKDNVDHEVITISKQGEQRRTAVETV
What are the official names of this protein?
WAT1-related protein At2g37460.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CASP1_PICGL
Sequence: MMQAESGSAEAKGPLPPPVGRKRRGLGILDFLLRLLAIGATLSAAITMGTTNETLQFFTQFFQFKARFYDLSAFIYFVIANAIVGGYLLLSLPISILNIVRPRAASSRVFLIFFDTVMVAVCTSGAAAAVAILYVARKGNSRTNWFAICQRFNSFCNQAIGAVSASFAGVVFLILLVLLSASTLYRRRP
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, PgCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: SIGA_CHLMU
Sequence: MRMDTLDSQAADAAQEEEIQRKLEELVTLAKDQGFITYEEINEILPPSFDSPEQIDQVLIFLAGMDVQVLNQADVERQKERKKEAKELEGLAKRSEGTPDDPVRMYLKEMGTVPLLTREEEVEISKRIEKAQVQIERIILRFRYSTKEAVSIAQYLINGKERFDKIVSEKEVEDKTHFLNLLPKLISLLKEEDSYLEERLLALKDPALSKQDQAKLNDELEKCRIRTQAYLRCFHCRHNVTEDFGEVVFKAYDSFLQLEQQINDLKVRAERNKFAAAKLAAARRKLYKREVAAGRTLEEFKKDVRMLQRWMDKSQEAKKEMVESNLRLVISIAKKYTNRGLSFLDLIQEGNMGLMKAVEKFEYRRGYKFSTYATWWIRQAVTRAIADQARTIRIPVHMIETINKVLRGAKKLMMETGKEPTPEELGEELGFTPDRVREIYKIAQHPISLQAEVGDSGESSFGDFLEDTAVESPAEATGYSMLKDKMKEVLKTLTDRERFVLIHRFGLLDGRPKTLEEVGSAFNVTRERIRQIEAKALRKMRHPIRSKQLRAFLDLLEEEKTGSGKIKSYKN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA, Sigma-66, Sigma-70, Sigma-A.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1253_STAAB
Sequence: MNELEFVTKHRRHLHQHPELSLHEFETTAYIKAFLDSLNIKYDCPLETGVIAYLEGNDSHTIAYRADIDALPILEENDVPYRSQSDHVMHACGHDGHTTALMLFVQRCKDMQDSGQLPQNVVFIFQPAEETGGGANRLIKAGAFDKYPIEAVFGIHVNPFADEGIAVIRDEEITASATEYRFFLTGLSSHVADKEQGHSCGEALQHVLTQISQIQQFHLNGLKRNIVHIGHFKAGEAINTVPSNGYLEGTIRTYDIDDLTIVKNQMQKIAESVKLLFNVDCEVKFAEGYPPTINSPKLRTQIEDALIKADLNVYDKPTPFLFGEDFSFYGQQLAPAYFVFIGTRNEDKGFVTGLHTSHLNFDEKVLINVVNFYENLLNNYKEV
What are the official names of this protein?
Uncharacterized hydrolase SAB1253.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: DCUP_BACVZ
Sequence: MSKREAFNDTFLKAARGEKTNHVPVWYMRQAGRSQPEYRKLKEKYGLVEITHQPELCAYVTRLPVEQYGVDAAILYKDIMTPLPYIGVDVEIKNGIGPVIDQPVRSAADIEKLGELNPEQDVPYVLETIRLLVNEQLNVPLIGFSGAPFTLASYMIEGGPSKNYNKTKAFMHSMPQAWKMLMDKLADMIIVYAKAQINAGAKAIQIFDSWVGALNREDYRQFIKPVMDRIFRELSAEQVPLIMFGVGASHLAGDWHDLPLDVVGLDWRLGIDDARKQGITKTVQGNLDPSLLLAPWEVIEKKAKAILDQGMKTDGFIFNLGHGVFPDVNPETLKKLTAFVHEYSAAKKTEQSS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PSEFS
Sequence: MNQERVFKVLLGPHVSEKATVLADKKGQFVFKVATDATKLEIKKAVESLFSVKVERVTTLNVLGKSKRTARGLGKRNDWKKAVISLQPGQDLDFSSSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: DOED_HALED
Sequence: MTTHKDLIDRDRKVTFHASTHLRDFAHGDAPGRVITGGKGIKIVDKDGREFIDGFAGLYCVNIGYGRSEVAEAIYQQALEMSYYHTYVGHSNEPQIALSEKILELAGPGMSKVYYGMSGSDANETQLKIVRYYNNVLGRPQKKKVISRMRGYHGSGIASGSLTGLKAFHDHFDLPIETIRHTEAPYYYHRAAEQEGMTEREFSKHCAAKLEEMILAEGPDTVAAFIGEPVLGTGGIVPPPEGYWDEIQAVLTKYDVLLIADEVVCGFGRTGSDFGSHHYGIKPDLITIAKGLTSAYQPLSGVIVGDRVWEVLEQGTGEYGPIGHGWTYSGHALGCAAGLANLAIIEREGLTANAAETGAYLQERMKAAFADHPVVGQVRGVGMMAALEFSVDPAARRHFDPSLKVGPRMSAAALEEDLIARAMPQGDILGFAPPLTTTREEVDEIVARTERAVNKVTDALTREGAIQAA
What is the function of this protein?
Involved in the degradation of ectoine, which allows H. elongata to utilize ectoine as both a carbon and a nitrogen source for growth.  Probably catalyzes the conversion of L-2,4-diaminobutyrate (DABA) to L-aspartate beta-semialdehyde (ASA) by transamination with 2-oxoglutarate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, Diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_MYCS5
Sequence: MKNNHIPVLLNEVLDNLALKENGIYIDLTLGMGGHSKEILKRIPKGKLIAFDKDDFAIKNASKTLSEVANNFEIIKSDFKDFKEELSNLGIYKVDGILADLGISSPQIDNAERGFSYLKNSALDMRMDQSQKLSAYDVVNLYPVEKLEYILKTYGEVKNYKYIASKIIEARPINTTLELANLIKSVTPQKLLKLKNPAKNVFQAIRIEVNNELDSIHQMLSSVEDLLKVNASLLIISFHSLEDKIVKNYFQELTKPKLPSKMPIQEDKFFATRRIYPSKQELNLNSRSKSAKLRILTKIKD
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDA_HELPX
Sequence: MFNYEELFQTHKTPFYLYDFDKIKQAFLNYKEAFKGRKSLICYALKANSNLSILSLLAHLESGADCVSIGEIQRALKAGIKPYRIVFSGVGKSAFEIEQALKLNILFLNVESFMELKTIETIAQSLGIKARISIRINPNIDAKTHPYISTGLKENKFGVGEKEALEMFLWAKKSAFLEPVSVHFHIGSQLLDLEPIIEASQKVAKIAKSLIALGIDLRFFDVGGGIGVSYENEETIKLYDYAQGILNALQGLDLTIICEPGRSIVAESGELITQVLYEKKAQNKRFVIVDAGMNDFLRPSLYHAKHAIRVITPSKGREISPCDVVGPVCESSDTFLKDAHLPELEPGDKIAIEKVGAYGSSMASQYNSRPKLLELALEDHKIRVIRKREALEDLWRLEEEGLKGV
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: GLHA_RAT
Sequence: MDCYRRYAAVILVMLSMVLHILHSLPDGDLIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKSFTKATVMGNARVENHTDCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2M_RHYNA
Sequence: MNPLIFTLITSTIVLGTMIVMTSSHWLMIWMGFEMNMLAIIPMLMKQYSPRSMEAATKYFLTQATASMLLMLAIIINLVYSGQWTFTKLMNPTASIIMTVALAMKMGLAPFHFWVPEVTQGISLLSGLILLTWQKLAPLSVLYVISPIINLDLLLTMSILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTSILIFNPMMTLLNLSLYILMTATTFTLFMTTSTTTTLALSHTWNKMPLITSSTLIIMLSLGGLPPLVGFLPKWMIIQELTKNNNIILATLMAITALLNLFFYMRLTYATSLTMFPTMNNMKIKWQFNHTKQTKCLPMLIVLSTMTLPLAPAMILLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YACG_RHIME
Sequence: MRGGGKKNGSNVEPLRATRPCAECGRPSVREHYPFCSERCRNVDLNRWLSGSYAIPVADDESKADDGDER
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: VSXL2_MOUSE
Sequence: MVGLSAHHRPLGCRLLILFCLLHPGASGQPYPTSNTAGEEALSVQGVRGSSVELECRTGPAPMAVLWSFTPLGSLVLQPVAVTSGASSKVESGALALGVVSLRNSSLVIEELREGARGHFLCQTLLVSGGQVHTAYLYLMLTVLVPVSKPRVQLNDPSPVEGVSVVATCAVREGTEPLTFSWHHHMPQGPGEVLVGLSEPRLQLDPVNRTHLGWYTCSVSNVVNQLKSDGAFLDVIYGPDKPVITVEPLGFSEDGFWASEREEVTLSCLAASNPPSHYVWFRDDSQIHTGPTYIIASASRTHTGLYTCLAHNRHLDTHTQTTVQLIIYYPPEGQPSCAVLPTLGVVTLLCTWPGGFPNAQLHWEGPQGIGPSASGNVTWSYTTTGLPNGSIFSCTGQHPTLAMPIFCRVTLWEPPGSPTCWTTATVGDQYIMLSCEWPGGEPPAMLSWLDRQQSLGDLGSSQAVHLLQAQSDLAGREFTCQGSHPLTAPGSHCRLRLEVPQLTVAEPRVSVLEGEEAWLGCALQRGTPPAQLLWLGPQQQQLEGSTPGFILHPEGTHLRLQVRDADPAHHRGTYQCVARNALGNSSQSVLLEVLSECKGFVCPCGYPTPPNVTISRLTYRRQRREVQLQWAIYGPGNLTGFLVQQRASVPSSEAGAWEVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHHTAGYPSEVKTPVDPAFSAYPAVLGAAGTGVVVALATSLLVFQYAARHPHTFPCTETASTTSSSDPIQESIDAPVNVTITVTATP
What are the official names of this protein?
V-set and immunoglobulin domain-containing protein 10-like 2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CITD_ECOSE
Sequence: MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXPE4_RAT
Sequence: MKMMASRKSLWVLLFIVIFWISFTVFRNPVKLWAVFKLPASFNQWDLIMKSSCPKVPLNPSVSPTETELRIREILEKLNKQIPPRPFAHLNNTTSATHSIATILNPQDTYCVGDQLDILVEARDHLRNRKGYGGDFLRARMSSPALKAGASGKVTDFNNGTYLVSFTLFWEGQVSLSILLMHPSEGVSALWRARNQGYDRIIFSGHFVSGASQVHTDCALVLNSSVELCQYLDAQDQEAFYCVKPPNVPCAAITHMHSKNKDISYLSQQERSLFERSNIAVEIMGKSNVISVSKCNKAVPVKKKCKFGMASAIPTGHVWKNTWNPASCSLAPIKMKDCLRGKLVHLMGDSTMRQWMEYFKSKINTLRPVDLHETGRLQHQLAVDLDEKINIQWQKHGFPLIGSLVYSVKEIENTARIIDRIGGEKNTVIVFSLGQHFRPFPIDVFIRRALSVHRALQRLLLRSPDTLVVLKTENTRELNNDMERFSDFHGYTQYLALKNIFQDLRVGVIDAWDMTVAYGTNDVHPPEEVVRSEINIFLNYIC
What are the official names of this protein?
NXPE family member 4, Protein FAM55D.
What is the protein family that this protein belongs to?
Belongs to the NXPE family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_HYDCU
Sequence: MIETDRIVGGQSLEEDMYVQPTVRPQIITDYIGQQAVREQLQLSINAAKMRQEHLDHVLLYGPPGLGKTTLSNIIAQEMGVTLRQTSGPVIEKPGDLAAILTRLEPHDVLFVDEIHRLSPIVEEVLYPAMEDFQIDIIIGEGPAAQSVKIDIPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYSIEELAQIVTRSANILGLSAEPDGALEIARRSRGTPRIANRLLRRVRDYAQVKGNGVITAEIADLALNLLEVDPLGLDKMDRRLLELLIQKFESRPVGIDSISAALGEERGTIEDVIEPFLVQQGFLIRTPRGRVVTQTAYRHLGLTMPERNLEDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.