PharMolix/UniProtQA huggingface dataset:
Protein: YKF3_YEAST
Sequence: MWLSLYRRKNIAGPLPCVLIFITSKNCMYLFILSIRRKMNDGPRLWYFFRTLFFIGPFVVIIRLSLRVVVPLLQRRALYIIAVLIVVIAVVINMFFMSQLLPHFIGHNRRRYHAGTRPVLLLQK
What are the official names of this protein?
Putative uncharacterized protein YKL053W.
Protein: FUR_CUPMC
Sequence: MPSPADLKNIGLKATVPRLKILEIFQTSEQRHLSAEDVYRILLNEHMDIGLATVYRVLTQFEQAGLLSRNNFESGKAIFELNEGKHHDHLVCLDCGRVEEFFDADIEQRQQSIARERGFALQEHALSLYGNCTKDDCPHRPRR
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.  Regulator for biosynthesis of the siderophore alcaligin E.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_AETGR
Sequence: MVTLKADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGKIAQIPVSEAYLGRVINALANPIDGRGKISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTSLQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYREQHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSQLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFSSDLDKATQNQLARGQRLRELLKQSQSAPLTVEEQIMTIYTGTNGYLDGLEIGQVRKFLVQLRTYLKTNKPQFQEIISSTKTLTDEAESVLKEGIQEQLERFLLQEKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TSR3_SACS2
Sequence: MKVYIIDYHKDDPKRCTGKKLVKLKIAEFTRVGKGVVLDPFAQITLSNKDKDIVRRIGITIVDTSWNNTSQSEFKNIRGEHRRIPILFAGNPIHYGIAYKLSSIEALIATLYIVDEVEEAIKLSNVVKWGHTFIELNKELLEAYKNKTEEDIKKIEREIIEKILEK
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase, 20S S rRNA accumulation protein 3 homolog, SsTsr3.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS7B_HUMAN
Sequence: MVSPATRKSLPKVKAMDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARKERKSKNS
What is the function of this protein?
Putative oxidoreductase.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 7B, Short-chain dehydrogenase/reductase family 32C member 1, Protein SDR32C1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TAL_METAM
Sequence: MANLFDQLKEFTTIVADTGDVEAIKSVKPYDATTNPSLLLKASTLPQYAPLIDEAIAYAKSQSGDKAQQIEDAADKLAVLIGQEILKHIPGKISTEVDARLSFDTDAMVQKGRKLIKLYADAGISKDRVLIKLASTWEGIKAGEILEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKAKTGENYTSETDPGVLSVRKIYAYYKEHGYKTVVMGASFRNTGEITALAGCDRLTVSPNLLERAEGYRRYLPRVLVDNGATKQRPALLTEKEFRFDQNEDAMATEKLAEGIRGFVVDQNKLEKALAEKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA_METST
Sequence: MFKLVLSDPSIFKTSFDAISSIVDEVQIEVDSDGLRLNAIDRSHITYVHLELKESLFDIYECDKPIKLNLDTEELMKVLKRSKNDDVMELTVDVGNLILTFEGAVKKTFKVKLIDLEYDTPSQPDIPYDIKIPIPVSILKEAIQDIEIVSDRVSFEVDEDKLTLEAVGDFADAKIEYLHGEKINEKARAVYAISNIKEMLKAEKFSDNTYLSIGTDMPLTLYLELLNEEGLLSFLLAPRLEEED
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: GPX_PROCL
Sequence: MSLENGTDVSFEEFRGKVVLVINVATYUGLTVPSYTQMNALAEFYVDQDFVILGFPCNQFEMLEPAANAEIMNGIRYVRPGDGFEPLMTLFEKTEVNGATEDPLFTFLKSACESTYTEFYSSLFYEPIRIGDIQWNFEKFLIGKDGKPYTRYHPDVVDPEALKDDINTLLSA
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione (By similarity).  May defend against reactive oxygen species that accumulate during the immune response.
What are the official names of this protein?
Glutathione peroxidase, PcGPx, Se-PcGPx.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: DIUH_ZOONE
Sequence: TGAVPSLSIVNPLDVLRQRLLLEIARRRMRQSQDQIQANREMLQTI
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules.
What are the official names of this protein?
Diuretic hormone, DH, Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: MGSA_SALDC
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RBM23_HUMAN
Sequence: MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTPQTM
What is the function of this protein?
RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor (PubMed:15694343).  Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity (PubMed:15694343).
What are the official names of this protein?
Probable RNA-binding protein 23, CAPER beta, CAPERbeta, RNA-binding motif protein 23, RNA-binding region-containing protein 4, Splicing factor SF2.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSPL_AERHY
Sequence: MAGEIFVSESLVIRLGTNAQQPVEWLVWSAKEEEIIASGILASAHALGELRERAGGRPVVTLVPGSDLIFRRVSLPGKYSRQAAAALPYLLEEQIASDVDELHLVVLGHEGHEVDLMAVDKEKMQIWLGWLQQAGLKSQQLLPDVLALPPAADGWSALQLGKEWLLRQGPCQGIVADESLLAMLLAAEADPVTIHSHTPLPAIPAANWLAADPELPMLLLAKGALNCQANLLQGPYRPQTEYSRYWLQWRKVAVVAGLLLLVALTQRGMHLYQLAEQDKALKAEIRQVYTRIFPGENRIVNVRSQMAQHLKLLGQTPQDGVLLLLTELAPTFAEVPGLKPQVLRFDAARGELRLQVTAPGFAEIERFRELAGKRFEVQQGEGAQHRGQG
What is the function of this protein?
Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in the complex assembly and recruits ExeM resulting in a stable complex in the inner membrane.  Provides thus a link between the energy-providing ExeE protein in the cytoplasm and the rest of the T2SS machinery.
What are the official names of this protein?
Type II secretion system protein L, T2SS protein L, General secretion pathway protein L.
What is the protein family that this protein belongs to?
Belongs to the GSP L family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLO_CAUVN
Sequence: MTDIAPDTGVLDDVVSAFQIENLPVRGRVVRLGAAIDEVLTRHDYPEPVANLLGEACALAALVGSSLKFEGRLIVQAQGDGPVRYVVVDYDTSGGLRGYCRFDPEEVAAVSEGFVRPGAKTLLGGGVFIMTLDQGPDMDRYQGVTPIEGETLALCAEQYFAQSEQTPTRVRLAVGQADTGQGATWRAGGILIQVIAGDQARGETQDAWTHVQALFETTGEDELIDPTVSTPTLLWRLFNEDGVRLLDEKPLKAFCRCSEDRIGVVMDSFSAEEVAEMVEPDGKIHVTCEYCSRIYKLDPPGA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_PANGI
Sequence: MPTITSYFGFLLVALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ZFAN1_HUMAN
Sequence: MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIIDSKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKPMFFCHRWSIGKAIDFAASLARLKNDNNKFTAKKLRLCHITSGEALPLDHTLETWIAKEDCPLYNGGNIILEYLNDEEQFCKNVESYLE
What is the function of this protein?
Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover.  SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress (PubMed:29804830).  Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome (PubMed:29804830).  This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during recovery from arsenite stress, and hence avoiding aberrant cytoplasmic SGs degradation via autophagy (PubMed:29804830).
What are the official names of this protein?
AN1-type zinc finger protein 1, Zinc finger AN1-type-containing protein 1.
Protein: PYRG_LISMO
Sequence: MTKYIFVTGGVVSSIGKGITAASLGRLLKNRGLSVTIQKFDPYINVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKVYSEVIKKERRGDYLGGTVQVIPHITNELKDRVFRAARMTNSDIIITEIGGTVGDIESLPFLEAIRQIKGDVGAENVLYIHTTLIPYIKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEQPVSQEMKDKIALFCDIKASEVIESRDEETLYNVPLSLQKQKMDDIVLEHLQLEAPQAEMTDWKNLVHRVKNLSKKVRIGLVGKYVSLQDAYLSVAEALRHAGYDHDAEIEIDWIDSEKVTKENVAEIMKDVDGILVPGGFGDRAIEGKIAAIEYARVNKVPYFGICLGMQLATVEFARNVLGLEGAHSAEIEPETNHNIIDLLPEQKNIENMGGTLRLGLYPARIKQGTKAEAAYGTTLVEERHRHRYEFNNEYREQMEEAGMIVSATSPDGRLVEVVELIDHPWFVACQYHPEFISRPNRPQSLFKDFVGAALKNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SLAP_GEOSE
Sequence: MDRKKAVKLATASAIAASAFVAANPNASEAATDVATVVSQAKAQFKKAYYTYSHTVTETGEFPNINDVYAEYNKAKKRYRDAVALVNKAGGAKKDAYLADLQKEYETYVFKANPKSGEARVATYIDAYNYATKLDEMRQELEAAVQAKDLEKAEQYYHKIPYEIKTRTVILDRVYGKTTRDLLRSTFKAKAQELRDSLIYDITVAMKAREVQDAVKAGNLDKAKAAVDQINQYLPKVTDAFKTELTEVAKKALDADEAALTPKVESVSAINTQNKAVELTAVPVNGTLKLQLSAAANEDTVNVNTVRIYKVDGNIPFALNTADVSLSTDGKTITVDASTPFENNTEYKVVVKGIKDKNGKEFKEDAFTFKLRNDAVVTQVFGTNVTNNTSVNLAAGTFDTDDTLTVVFDKLLAPETVNSSNVTITDVETGKRIPVIASTSGSTITITLKEALVTGKQYKLAINNVKTLTGYNAEAYELVFTANASAPTVATAPTTLGGTTLSTGSLTTNVWGKLAGGVNEAGTYYPGLQFTTTFATKLDESTLADNFVLVEKESGTVVASELKYNADAKMVTLVPKADLKENTIYQIKIKKGLKSDKGIELGTVNEKTYEFKTQDLTAPTVISVTSKNGDAGLKVTEAQEFTVKFSENLNTFNATTVSGSTITYGQVAVVKAGANLSALTASDIIPASVEAVTGQDGTYKVKVAANQLERNQGYKLVVFGKGATAPVKDAANANTLATNYIYTFTTEGQDVTAPTVTKVFKGDSLKDADAVTTLTNVDAGQKFTIQFSEELKTSSGSLVGGKVTVEKLTNNGWVDAGTGTTVSVAPKTDANGKVTAAVVTLTGLDNNDKDAKLRLVVDKSSTDGIADVAGNVIKEKDILIRYNSWRHTVASVKAAADKDGQNASAAFPTSTAIDTTKSLLVEFNETDLAEVKPENIVVKDAAGNAVAGTVTALDGSTNKFVFTPSQELKAGTVYSVTIDGVRDKVGNTISKYITSFKTVSANPTLSSISIADGAVNVDRSKTITIEFSDSVPNPTITLKKADGTSFTNYTLVNVNNENKTYKIVFHKGVTLDEFTQYELAVSKDFQTGTDIDSKVTFITGSVATDEVKPALVGVGSWNGTSYTQDAAATRLRSVADFVAEPVALQFSEGIDLTNATVTVTNITDDKTVEVISKESVDADHDAGATKETLVINTVTPLVLDNSKTYKIVVSGVKDAAGNVADTITFYIK
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein, Surface layer protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S-layer with hexagonal symmetry.
Protein: EPHA8_HUMAN
Sequence: MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation.  With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth.  During development of the nervous system also plays a role in axon guidance.  Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH-like kinase 3, EK3, hEK3, Tyrosine-protein kinase receptor EEK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection. Early endosome membrane. Note=Undergoes clathrin-mediated endocytosis upon EFNA5-binding and is targeted to early endosomes.
Protein: UNC4_CAEEL
Sequence: MIGALHACVDAEPKIINDIWADFWKSQINSVLLNPSDGSETYLASDNGKSTSSREQSTSPDDDNLLMNEDDGIALEDDNDTGESAAKRRRTRTNFSGWQLEELESAFEASHYPDVFMREALAMRLDLLESRVQVWFQNRRAKWRKREQNRNGSSEIKKDDGEQMETKALPTFPFSIDSILAVSRVPRGRRPNAKYPRVQACKNLSPFMIPLFPITQPGGNVIREKSPPLPTQQSQIVATNALTTVAELLKSV
What is the function of this protein?
Transcription factor (PubMed:1347150, PubMed:7904971, PubMed:28056346).  Involved in motor neuron fate determination and maintenance (PubMed:28056346, PubMed:34388088).  In concert with unc-37, represses the expression of VB-specific genes such as ceh-12, thereby preventing the adoption of VB motor neuron fate (PubMed:7904971, PubMed:9165118, PubMed:10557206, PubMed:11245684, PubMed:17289921).  Regulates synaptic specificity and the pattern of synaptic input to VA motor neurons, and, depending on context, acting in opposition to, or supported by, Wnt signaling (PubMed:1347150, PubMed:7904971, PubMed:7555714, PubMed:22619391).  Required in patterning of the synaptic outputs of the postmitotic DA class cholinergic motor neurons (PubMed:34388088).  Acts as a transcriptional repressor to counteract gene activation by transcription factor unc-3 in a subset of motor neurons, probably by binding to specific promoter elements (PubMed:28056346).  Has no role in axonal guidance or outgrowth (PubMed:1347150).
What are the official names of this protein?
Homeobox protein unc-4, Homeobox protein ceh-4, Uncoordinated protein 4.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Unc-4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_BACC7
Sequence: MEYKNTLLMPKTEFPMRGNLPKREPAMQEKWAEMNIYEKVQEHTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDFIVRYKSMTGFCAPYVPGWDTHGLPIEQALTNKGVKRKEMTVAEFRKLCAEYAYEQVERQREQFKRLGVRADWDNPYITLEPAYEAQQIKVFGDMAKKGYIYKGQKPVYWSPTSESALAEAEIEYQDKKSASIYVAFPVKDGKNVLEGDEKYIIWTTTPWTLPANLGISVHPELEYAIVKVNGEKYIIASELFETVAKTLEWENAEVVKTVKGSELEYTVAKHPFYDRDSLVMLGDHVTTDAGTGCVHTAPGHGEDDFIVGKKYGLEVLCPVDDKGVLTEEAPGFEGLFYDKANKPITEKLEEVGALLKLTFITHSYPHDWRTKKPIIFRATAQWFASIEAFRKELLEAVAETKWVPAWGETRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGDPIITDETINHVADLFREHGSNVWFEREAKDLLPEGFTHSGSPNGEFRKETDIMDVWFDSGSSHQAVLEERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSIGNIVVPKKIMDQLGGDILRLWVSSVDYQSDVRISDDILKQVAEVYRKIRNTFRFLLGNLDDFKPSENTVAVAELREVDRYMLVKLNDLITKVKEAYETYDFAAVYHAIHNFCTIDLSSFYLDFAKDILYIEGANHEDRRAIQTVLYDVLVALTKLVTPILPHTADEVWPYIPGVTEESVQLTDMPEAVQLDGAEALKTKWDAFMTLRDDVLKALEVARNEKVIGKSLNASITLYPTAEMKAMLESINEDLKQLFIVSEYKLGGMMEEAPADAPKYEHTAVVVVQATGETCERCWVVSETIGKDAEHETLCERCATVVKENYVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ECOLC
Sequence: MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y249_ARCFU
Sequence: MSVEEISEKLKVDKLAICSDEISTVGLEPDLAAELKELIYVLVPAESFQGYLAVDGQYVVFRRDSRKCVLAIVEEERVRWCLRRLEEVLNGS
What are the official names of this protein?
Uncharacterized protein AF_0249.
Protein: PRZN_SERMA
Sequence: MQSTKKAIEITESSLAAATTGYDAVDDLLHYHERGNGIQINGKDSFSNEQAGLFITRENQTWNGYKVFGQPVKLTFSFPDYKFSSTNVAGDTGLSKFSAEQQQQAKLSLQSWADVANITFTEVAAGQKANITFGNYSQDRPGHYDYGTQAYAFLPNTIWQGQDLGGQTWYNVNQSNVKHPATEDYGRQTFTHEIGHALGLSHPGDYNAGEGNPTYNDVTYAEDTRQFSLMSYWSETNTGGDNGGHYAAAPLLDDIAAIQHLYGANPSTRTGDTVYGFNSNTGRDFLSTTSNSQKVIFAAWDAGGNDTFDFSGYTANQRINLNEKSFSDVGGLKGNVSIAAGVTIENAIGGSGNDVIVGNAANNVLKGGAGNDVLFGGGGADELWGGAGKDIFVFSAASDSAPGASDWIRDFQKGIDKIDLSFFNKEANSSDFIHFVDHFSGTAGEALLSYNASSNVTDLSVNIGGHQAPDFLVKIVGQVDVATDFIV
What is the function of this protein?
Has insecticidal activity against the locust M. palpalis.  When administered orally to locusts at a low dose it causes them to lie on their sides exhibiting sporadic limb movements and muscular twitching, followed by full recovery.  When administered at higher doses the same symptoms are observed, followed by death.
What are the official names of this protein?
Serralysin, Extracellular metalloproteinase, Zinc proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_FRASN
Sequence: MAGQLREYRRRIKTVQSTKKITKAMELIAASRIAKARARVAASRPYAEEITRVISAVASQTTIAHPLTTERPEPTRAAVVVITSDRGLAGGYSSNALKRAGELVELLREEGKEPLLYAVGRKAGTYYRFRGRPLAGDYTGFSEQPSYSDAKAVADALITAFTTPTEEGGVDEIHLVFTEYVSAMTQNAVAHRLLPMVLREHDEPPAGGPLPNYEFEPSAEAVLDALLPRYVESRLYAALLESAASESAARQRAMKSATDNAEDLIKTYTRAANRARQDAITQEISEIVGGANALASGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MET1_MYCHD
Sequence: MTDIRDTDALFALADRVTGFMPADEGRTLYETAVRYLGDGVGVEIGTYCGKSTVLLGAAARQTGGVVFTVDHHHGSEEHQPGWEYHDPSLVDPVTGLFDTLPRLRHTLDEADLYDHVVAVVGKSAVVARGWRTPLRFLFIDGGHTEEAAQRDFDGWARWVEVGGALVIHDVFPDPKDGGQAPFHIYQRALNTGDFREVNAYGSMRVLERTSGIAGQPL
What is the function of this protein?
Involved in the biosynthesis of 3-O-methylmannose polysaccharides (MMP), which are intracellular polymethylated polysaccharides implicated in the modulation of fatty acid metabolism in non-tuberculous mycobacteria (PubMed:30606802).  Specifically methylates the 1-OH position of 3,3'-di-O-methyl-4alpha-mannobiose, a probable early precursor of MMP, yielding the reducing end dimannoside of MMP (PubMed:30606802).
What are the official names of this protein?
MMP 1-O-methyltransferase, 3-O-methylmannose polysaccharide 1-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.