PharMolix/UniProtQA huggingface dataset:
Protein: HBB_STUVU
Sequence: VQWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAVLGNPKVQAHGKKVLTSFGDAVKNLDSIKNTFSQLSELHCDKLHVDPENFRLLGDILVVVLAAHFGKDFTPDCQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NAC26_ORYSI
Sequence: MGEQQQQVERQPDLPPGFRFHPTDEEIITFYLAPKVVDSRGFCVAAIGEVDLNKCEPWDLPGKAKMNGEKEWYFYCQKDRKYPTGMRTNRATEAGYWKATGKDKEIFRNHHMLIGMKKTLVFYKGRAPKGDKTNWVMHEYRLADASPPQPPPPPSSAEPPRQDDWAVCRIFHKSSGIKKPVQVPMQMPMQMQMPVAHQVPAANYQQQMAMASASIIQVPMQMQMPSMSDQLQMLDDFSTGSLMAPPPPPPSYSTLPGFPLQINGGAQQFVGNPSMYYQQQQQQQQQQMDMAAGGFVVSEPSSLVVSPQDAADQNNAADISSVACNMDATIWKY
What is the function of this protein?
Transcription factor that acts redundantly with NAC20 to regulate the expression of genes involved in the biosynthesis of starch and storage proteins in grain.  Directly binds to the promoters of starch synthase 1 (SS1), pullulanase (PUL), glutelin A1 (GLUA1), glutelins B4 and B5 (GLUB4 and GLUB5), alpha-globulin and 16 kDa prolamin, and activates their expression (By similarity).  Possesses transactivation activity in yeast (PubMed:27872632).
What are the official names of this protein?
NAC domain-containing protein 26, ONAC026, OsNAC26.
What are the subcellular locations of this protein?
Nucleus.
Protein: BMR1B_CHICK
Sequence: MPLLSSSKLSMESRKEDSEGTAPAPPQKKLSCQCHHHCPEDSVNSTCSTDGYCFTIIEEDDSGGHLVTKGCLGLEGSDFQCRDTPIPHQRRSIECCTGQDYCNKHLHPTLPPLKNRDFAEGNIHHKALLISVTVCSILLVLIIIFCYFRYKRQEARPRYSIGLEQDETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKGMLKLAYSSVSGLCHLHTGIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHNPASRLTALRVKKTLAKMSESQDIKL
What is the function of this protein?
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.  Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcription (By similarity).  Positively regulates chondrocyte differentiation (PubMed:24129431, PubMed:14523231).
What are the official names of this protein?
Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, Activin receptor-like kinase 6, ALK-6, RPK-1, Serine/threonine-protein kinase receptor R6, SKR6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NGA1_ARATH
Sequence: MMTDLSLTRDEDEEEAKPLAEEEGAREVADREHMFDKVVTPSDVGKLNRLVIPKQHAERFFPLDSSSNEKGLLLNFEDLTGKSWRFRYSYWNSSQSYVMTKGWSRFVKDKKLDAGDIVSFQRCVGDSGRDSRLFIDWRRRPKVPDHPHFAAGAMFPRFYSFPSTNYSLYNHQQQRHHHSGGGYNYHQIPREFGYGYFVRSVDQRNNPAAAVADPLVIESVPVMMHGRANQELVGTAGKRLRLFGVDMECGESGMTNSTEEESSSSGGSLPRGGGGGASSSSFFQLRLGSSSEDDHFTKKGKSSLSFDLDQ
What is the function of this protein?
Regulates lateral organ growth.  Functionally redundant with NGA2, NGA3 and NGA4.
What are the official names of this protein?
B3 domain-containing transcription factor NGA1, Protein NGATHA 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_BACAH
Sequence: MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKILEYEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_PHEZH
Sequence: MSEPAPAKRLYIKTYGCQMNVYDSERMADVLAPLGYGVTDDPAAADLVVLNTCHIREKATEKVYSELGQIKRLKEARRAEGQGMTIAVAGCVAQAEGEEIMRRQPAVDLVVGPQAYHQLPELIARAHRARGERLAADFAPDEKFDALATERRPTGVTAFLTVQEGCDKFCTFCVVPYTRGGEWSRPAEAIEAEARALAAKGVREVTLLGQNVNAYDGANGQGAGLAGLVRRLAKIPGLDRIRYTTSHPRDMDDDLIAAHAEVPELMPYLHLPVQAGSDRILRAMNRAHTAESYLRVIEKVRVARPDIAISGDFIVGFPGEREADFEATLQLVREVGYASCFSFKYSRRPGTPAAALPGQVAEEVKEERLQRLQALLEQQQLAFNAAQAGRVLPVLFEKTGRHPGQLIGRSPYLQAVHAHAPDRLIGQIVPVKVESGGRNSLAGVLELETA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP62_SYNP2
Sequence: MQITPDNIIFYQYQFVVINATLVYTWLTMALLVIGAAWVTKKLVVRPKLPPWQNFLEIVVDGIYQHIAEVTQQEPEPYLAFVGTLFLFILTANLLTVVPGYQAPTGSLSTTTALAIAVFIAVPIYGIRQRGILGYLKSYLQPTPIMLPFQIIGEFSRTLALAVRLFGNIMSGNLLAAILLALVPLFVPVAMNLLGLVFGVIQAYVFAILALVYIASAATVQEKKQSISMEENS
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 2, ATP synthase F0 sector subunit a 2, F-ATPase subunit 6 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FOLB_SYNY3
Sequence: MDTLNVKGIRAYGYTGYFDAEQFLGQWFEVDLTIWIDLAKAGQSDDLNDTLNYADAVAIVQKLIRESKFKMIEKLAEAIADAILGTGKTQQVKVALTKCQAPIPDFDGDVTLEILRSR
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
What are the official names of this protein?
Probable dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin aldolase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: HPCA_RAT
Sequence: MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels (By similarity).  May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (PubMed:15336960).
What are the official names of this protein?
Neuron-specific calcium-binding protein hippocalcin, P23K.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Association with membranes is calcium-dependent (PubMed:8360179, PubMed:1543495). Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (By similarity).
Protein: DUT_NITWN
Sequence: MSDPIKVDVRQLPHAEGLPLPSYQSTQAAGLDLIAAIGEQAPLVLAAGRRAMVPTGLVIALPDGYEAQVRPRSGLAARHGVTVLNSPGTVDADYRGEINVLLVNLGSEAFTIRRGERIAQMIVAPVTRVELVRAAALPATPRGSGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CYSG_NEIMA
Sequence: MNYFPIFANLAGRPVLVVGGGAVAARKISLLLKAGAEVRVAAKHLNAELSALAAENKILWLAEEFRAEHIRTVFLIIAASSDQALNRRVFHLAESCQKPVNVVDDRDHCSFIFPSVIDRNPVQIAVSSSGSAPVLARLLRERLEALLPPSLGDMAEISGRWRDAVKGKLKSVTERRRFWEKQFNGRFAALVKNRQNTLAERELAGQLEQSRQNDQGGSVSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDGILSLVRRDAERIFVGKRARGGRTPQEDTNALMVRLAREGRRVVRLKGGDPFVFGRGGEELETLARHQIPFSVVPGITAAVGATAYAGIPLTHRDYAQSAVFVTGHRKADAPDIEWQTLARSRQTLVIYMGALKAALIAERLQQHGRSPDTPAAVISQGTLPAQKTATGTLANLAELAETAPNPALIVIGEVVGLHEKLAWFGENAKKESNPAEHAYFALDGLGTGQEQQAA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: HSLO_ECODH
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMVA_SALTY
Sequence: MFRQWLTLVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELLWIIDIYSLVMAGMVLPMGALGDRIGFKRLLMLGGTLFGLASLAAAFSHTASWLIATRVLLAIGAAMIVPATLAGIRATFCEEKHRNMALGVWAAVGSGGAAFGPLIGGILLEHFYWGSVFLINVPIVLVVMGLTARYVPRQAGRRDQPLNLGHAVMLIIAILLLVYSAKTALKGHLSLWVISFTLLTGALLLGLFIRTQLATSRPMIDMRLFTHRIILSGVVMAMTAMITLVGFELLMAQELQFVHGLSPYEAGVFMLPVMVASGFSGPIAGVLVSRLGLRLVATGGMALSALSFYGLAMTDFSTQQWQAWGLMALLGFSAASALLASTSAIMAAAPAEKAAAAGAIETMAYELGAGLGIAIFGLLLSRSFSASIRLPAGLEAQEIARASSSMGEAVQLANSLPPTQGQAILDAARHAFIWSHSVALSSAGSMLLLLAVGMWFSLAKAQRR
What is the function of this protein?
Major efflux pump for acriflavine and other quaternary ammonium compounds (QACs).  Also required for resistance to methyl viologen (By similarity).
What are the official names of this protein?
Methyl viologen resistance protein SmvA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSA_SALTI
Sequence: MSIEIARIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQSSGHIRFHGTDVSRLHARERKVGFVFQHYALFRHMTVFDNIAFGLTVLPRRDRPTAAAIKTKVTQLLEMVQLAHLADRFPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQADAPDRVWREPATRFVLEFMGEVNRLTGTVRGGQFHVGAHRWPLGYTPAYQGPVDLFLRPWEVDISRRTSLDSPLPVQVIEASPKGHYTQLVVQPLGWYHDPLTVVMAGDDVPQRGERLFVGLQNARLYHGDQRIEPHEALALAESA
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MOAA_SALNS
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNNGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNGYRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELIKRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RS4_BACAA
Sequence: MARYTGPAWKLSRRLGISLSGTGKELEKRPYAPGPHGPNQRKKLSEYGLQLQEKQKLRHMYGMTERQFRRTFDQAGKMPGKHGENFMILLEARLDNLVYRMGLARTRRAARQLVNHGHIMVDGARVDIPSYRVKPGQTISVREKSNNLVVVKEAIEVNNFVPEYLTFDADKLEATYTRHAERAELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PER18_ARATH
Sequence: MALQFFSCKPKYTFLSSLLLLLLLSSSVAELSFNFYAGSCPGAELIVRNTVRSASSSDPSVLGKLLRLIFHDCFVQGCDGSVLIRGNGTERSDPGNASLGGFAVIESVKNILEIFCPGTVSCADILVLAARDAVEALGGPVVPIPTGRRDGRVSMAANVRPNIIDTDFTVDKMINIFSSKGLSVHDLVVLSGAHTIGAAHCNTFNSRFKLDPKGNLELIDASLDNSYAQTLVNKCSSSLDPTTTVVDNDPETSSTFDNQYYKNLLAHKGLFQTDSALMEDDRTRKIVEILANDQESFFDRWTESFLKMSLMGVRVGEEGEIRRSCSAVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 18, Atperox P18.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KCY_LACPL
Sequence: MAKQALQVAIDGPASAGKSTVAKLVAKRFGYIYVDTGAMYRAVTYWAMQQHVDLADEAAVITAMKSLKISFKPGEPDQLVFANQEDITAAIRQPDVTNNVSTIAALPQVRTILTEQQREMANAGGIVMDGRDIGTTVLPNAEVKIFLVASAAERAKRRYAENVKKGIDTPLAQLQAEIELRDHKDSTRKVSPLTQATDATLVDTTPMSIDEVVAAIAKIITKKQSSTI
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_SALAI
Sequence: MATIEGIVAREILDSRGNPTVEVEVGLDDGTIARAAVPSGASTGAFEAIELRDGDKDRYLGKGVATAVSNIEDKIVDELIGYEASEQRLIDQKMLDIDGTDNKSELGANAILGVSLAVAKAAADSAELTLYRYLGGPNAHLLPVPMMNILNGGAHADSNVDIQEFMIAPIGAPTFREALRSGAEVYHALKSVLKKKDLATGLGDEGGFAPNLPTNAAALDLIAEAVEKAGYRLGTDIVFALDVAATEFFANGTYTFEGAAKTAEEMSSYYTKLADAYPIVSIEDPLAEDDWSGWQTLTASVGDRIQIVGDDLFVTNPQRIARGIAEHAANAVLVKVNQIGSLTETLDAVDLAHRAGFRCMMSHRSGETEDTTIADLAVATGCGQIKTGAPARSDRVAKYNQLLRIEEELADAARYAGAGAFPRYRSA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL23_PSEPG
Sequence: MNQERVFKVLLGPHVSEKATVLAEKKGQFVFKVATDATKLEIKKAVEGLFNVKVENVSTVNVLGKTKRTARGLGKRNDWKKAIVSLQPGQDLDFSSSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: COBQ_METTH
Sequence: MSAKCIMVQGTSSSAGKSVMVAALCRIFSRRGYRVAPFKSQNMSLNSFTTAENREIAVAQVLQAEAAGIEPSHHMNPVLLKPKEDFTSQVIVHGRPAGNMNFQDYQTEFRDTALEAIRESLEYLKSRYELIVIEGAGSPAEINMRDRDLANMEIAHLADADVILVADIDRGGVFASIAGTLMLLDERDRSRIKGVVINKFRGNIDILMPGIERIEEITGVPVLGVLPYDEGLKLPEEDSASLSQRKYRGRGDIRVGVMRLPRISNFTDIDPLEYEEDVAVRLIETGDSLDDLDAIIIPGTRNTISDLIHLEENGFADEIRDLSREIPVFGICGGFQMLGKRILDDARQESSEGSVDGLGLLDCETHFTGEGKIISQSQGRVLGNGIFSGMRGETVEGYELHEGTTVLGDVKPLLRVDRGFGNTRSGGFDGAVDGNVAGTYFHGIFHNFRFRRYFTNLLRERKGIEPLEYLDDNFSASRRFSIDRLAEIVEENMDLSIIEEILEG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity).
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: HTPX_HAEI8
Sequence: MMRILLFLATNMAVMLVLGIILNVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALRSVDGEVITQPRNQTERWLIDTVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLNTFVIFLSRVIATAVASSRNNNGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQRLQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LDH2_LISMF
Sequence: MKPRKVMIIGAGNVGTAAAHAFVNQKFVEELILVDLNKERVEGNRKDLADAAAFMPGKMDITVRDASDCADVDIAVITVTAGPLKEGQTRLDELRSTSRIVSSIVPEMMKGGFNGIFLIATNPCDIITYQVWKLSGLPRERVLGTGVWLDTTRLRRLLAEKLDIAAQSIDAFILGEHGDSQFPVWSHSSIYGKPVNEYSVEKLGEALDLKQIGETARDTGFEIYHQKGCTEYGIGGTIVEICRHIFSGSQRALTVSCVLDGEYGESGLAIGVPAVLSQNGVKEIISLKLDEKEKEAFANSVAVIKKSIQSI
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR1_CAEEL
Sequence: MDVSYYDGPKDEVAEAMLKSAVTAMRLGQYEDGKGRLEEIMEFGTSNFQLLGTIYMYYGRVCRHLNHDAKALEFFEHELNMFKLIFNYPEACDSTRRIVEQALKMGKFPKARRFAEDLIDYTSNKKNGEKYIGQARILFASVCLEGCERDVESNQDEKKKLLSICAEQIAAVKLFNENNTEGAVSETKIMLLEAKCLSLDEKYEESRRKYQECIDFAIKTDQFEAVHIAYYDKALYAETDLLFFIIRDLRSALFYATKFGKERDVVKYKSKLSEEMLRNGEFHEAYLYGLEALVSIRKLGLNEYIGDVLLTIAKCLIALGKRRQAAYFIILGSVLTINQNSFKLFYEQIDVAMNQERSETATDQDVCLAIDSSPDPTSSNDMINKFVVELEHATNVETWEMIVNGIIDDQKKPVAIEKKENEEPVDMMDLIFSMSSRMDDQRTELPAARFIPPRPVSSASKKTTKSHRILPGLRANWTKVQSMKFDGHTMNRILKRSKKSKSSLDSTNSMQGDDTRSDDVTMTSK
What is the function of this protein?
In the 1-cell embryo, probably together with gpr-2, controls nuclear rotation and spindle elongation during mitosis (PubMed:14534135).  Complex of gpr-1 and gpr-2, in association with lin-5, activates G-protein signaling to affect mitotic spindle force (PubMed:12730122).  Polarity determinants (par genes) may regulate lin-5/gpr-1/gpr-2/goa-1 locally to create the asymmetric forces that drive spindle movement (PubMed:12730122).
What are the official names of this protein?
G-protein regulator 1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton, spindle. Note=Located to the spindle and cell cortex when in complex with lin-5 and gpr-2 (PubMed:12730122). During early embryogenesis, cortical localization changes with the cell cycle. In one-cell embryo, uniform cortical localization from prophase to metaphase and posterior enrichment during anaphase. In the 2-cell embryo, uniform cortical localization in AB blastomere and posterior cortical enrichment in P1 blastomere during interphase. In P1, uniform cortical localization from prophase to early anaphase and then posterior cortical enrichment during late anaphase and telophase (PubMed:14534135, PubMed:12730122). Cortical localization and asymmetrical distribution is regulated by the csnk-1-mediated regulation of pkk-1 (PubMed:18694560). Enriched at the contact site between EMS and P2 from prophase to prometaphase (PubMed:14534135).
Protein: NFUA_CROS8
Sequence: MIRISDAAQAHFAKLLASQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVTLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RL28_NOSS1
Sequence: MSRRCDLTGKKANNAFAVSHSHRRTKRLQQVNLQNKRVWWPSGNRWVKLKLSTKAIKTLEVKGLEAMAKEAGINLNHY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: D1039_DICDI
Sequence: MAAELPFYIASSVEELVKKHVEGVEVDKNYSIFHYLSTCNNLVKQADIYKSEGDIERTYIYSLRFCILIFEKLQKHPDFNKESFTKSRNEIKRKAELKLKELEGLKETLKKGYERIQHKKEEERKRIEREKEKERIFKQEKLKLEREQQLLREEEEQRKREDLELESEIQRLKEVEDFENRKLQAQKNIKRATSARTFELLRQEALLEERKRLQGIETEKKRILAEKQEALEKEFQQQLFEQQEKERLEKERLEKEEQLRLASLPPPPPDYSSFDSDQLLNLIENNNKKLENNNQTDDKLDNEFLLDPSFLPPPPPIITQPSPSQEKKDNNNNNNNKNTTAQLPLSITQPPHMPNNEKKLPPIYNSTSPIQFGYPSLNNSVNNPPSFSLQNNTPLIQQYKQQQQQQPIQSPTNNINRPNIPQYNNYNAKPLSSNLNPLPPQYQPQQQQQYQQQQQQQQYQQQQQYQQQQQQQQQQQQQQQHQLPKLPQYQPIENKSISANGLAQSPAVNTPSITPTTNKPNIDSSEASKKYSKLRKIIVHGEVFQEFMRLAENNTKRSIETCGILSGTLSNDVFRITTIIIPKQEGTTDTCNTIEEHEIFEYQLENDLLTLGWIHTHPTQDCFLSAVDVHTHCSYQYLLQEAIAVVISPMANPNFGIFRLTDPPGLETVQKCKLKSFHPHPPVNGIPIYTKVDHVDLIWGKKSDSKVVDLRFLKK
What is the function of this protein?
May be a zinc metalloprotease that specifically cleaves ubiquitin chains.
What are the official names of this protein?
Probable ubiquitin thioesterase DG1039, Developmental gene 1039 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67C family.
Protein: MC132_MCV1
Sequence: MMNFSDPCLLGPSACNEDFFEELAREILPTPEAKALAARLLRRLGWHPSEGQCSWCPEAYEYLYDLQFRYTGPVPLVRKHPGSALIVRWMLDGLGHFLFCRPRVQGNPLTYHLSCMGSAIRTLELFREQAHSHLWEQGNLVDCYWSCSSDYGYEGKWGQQAVVRGALSGPWPRPDPPSLQLQCLCAIWRTCLLRGQSQAQKYTNWICARHLQLRPDTSTRDSDLLLQRC
What is the function of this protein?
Inhibits host NF-kappa-B activation stimulated by IL-1 and multiple PRR viral detection pathways.  Targets host NF-kappa-B component RELA/p65 for ubiquitin-dependent proteasomal degradation.
What are the official names of this protein?
Protein MC132.
What are the subcellular locations of this protein?
Host cytoplasm.