PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_MYCCT
Sequence: MIITRNWLKKYLNLDNISNDQINVALNSLGFEVDNVYDLNSLNSELVLGYVEQSKQIPDTHLKLNKVNIGTKSLQIVCGASNVDVNQFVIVAPINATIANGLTLTSKKIQNYESQGMICALNEIGINQSVINKEDQLKIYNVFDKNLDLKKYLGKDVKQIIGLDDYLFEIDLTLNRSDCLASFQILKELANYFDLEIKNYDNKFNDFKENDLDLKITISKKIEEQIKTISYSNFVLNNHLNKLDSIDDIFLKLNQISSTNNLINDLSLLSTLSTAQTHILIDLDKLKSFNLKLELINHNDKELLCLTSDNQIVNIIGLQTESKFSIDNNSKNVLNIMVNIEPNLMRKQQKLLNTSNINLQRYIKPINPNLFDLANLNLTSLLNSYNLVNKAYKVKVLKQTYKNKTEFEIKISEINDLLGTNLTIDQIKSLFKKLDFKITNKNDLLTFNIDPNRIDISSKNDLCEEVARLYSYDNIQEVALSFTSFKKPKNLNLKLENKLTNYLIGLGFNNTKTYSLTTQIDAKHWNLFNISDFINLLSPLSNLRQTYRTSLSKSLIDTAIYNHSINNKELKLFEIADIYNLNQLKQRHLVFLTSHHIYKNGLTHQLVENNFYYNKEILESIFDLYNLDFSQIKYVNNLDVIKEIHLYINATIYYQKQLVGFIYQLNPKFESENKLNKTFVCEINLDVLNELKNKTIEAKTLSKFQSSSRDLTIEISNDLIYQDVLLKAISDVKYITSSKVVDLYLDDKLAKNNTKALTIQFIFNDLDHQLTEAEINTEFEKIISNVKKMKVVIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC_MOUSE
Sequence: MVGYDAKADVRSNSKLEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKAALSTGFMFFWYELFCNLFHCIRREDR
What is the function of this protein?
Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria.  It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier, Solute carrier family 25 member 19.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL5_SULNB
Sequence: MSRMKQKYNDIVPALREECGVQNTMQTPKLEKIVISVGAGEEGRDSKLIANMADTISLIAGQKAVIVNAKKSVAGFKAREGAPSGIRVTLRGDNMYNFFDKLVSIALPRVKDFRGTPRKGFDGRGNYNFGLQEQLMFPEVEFDNIIKTHGMNITIVTSTEDDKQAFTLLEKLGMPFAKGRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MSHA_MYCVP
Sequence: MRLATEPASLPSGLPEPRRVAVLSVHTSPLAQPGTGDAGGMNVYVLQTALELANRGVDVEIFTRATSSADQPVVPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDIVHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDAPEPPMRSIGEQQVVDAADRLIVNTEHEAQQLVSLHQADPARIDVVHPGVDLATFTPGDRLAARAALGLDANSRIVAFVGRIQPLKAPDVLLRAAALLPDVQVLIAGGPSGSGLISRPGAGGLATPDNLVNLAAELGMTDRVTFLPPQSRDNLVQVYRAADVVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSGALVDGHDPGDWAGTLADVLAADPATLSRAAVDHAATFSWSHTVDALLAGYGRAIADHRARHQGQLARRSGRRFSMRRGVRA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: SCC4_CULQU
Sequence: MTSSQDACYISLLGLAEYFRTSSPPNIKKCIQCLQALFTFKPPLKVEARTHLQLGQILMAYTKNTELARNHLEQAWMLSENINNFDDVKFDTASLLAQLYQQQEQSSLAKPVLRKAIELSQHNVYWHCKLLFQLAQTHATDKEYALASELLAVGVESTDESNATYLKSLFLLSRAMIMMIERKSSDVLAILNQAGTIIDNAIQNIHLKEYLKVFFFVLQVCHYLQLGQVKTVKTSLKQLQQSIQTIMAPNWPSDEQIFGQNSTEMFMWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKSQENKPILAVFQIILLEHIIMCRLVMGNKSLAIKEIALAKDVCLSSSHKFLLKKHSPQLHCLLGLYSMSASLFDHAERQFYTCIQETTERDLKLFANLNLAIVYLRMKREPDLRAILDQVQQENSLCSNSQALMGSFYYVQGLNAFHKSSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMLKEPALEQEAYNNHLNFSQNLIADQLKCTKFQEHTLINWIQGDPPMPMLTTQEPMMGEPSQAAAMRVAAGAPGQQVIFQ
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: SSN3_GIBMO
Sequence: MPLRPHIGLGFPAHAYQKRHVEPHDRSTGYQPKVRITDRYRIIGFISSGTYGRVYKAVGRNGKPVGEFAIKKFKPDKEGEQISYTGISQSAIREMSLCSELHHINVIRLCEIVLEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATIKSIMFQLLNGCQYLHINWVLHRDLKPANIMVTSSGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFRRNQMQKIIEIMGVPTKDKWPLLSTMPEYNQLNTLANSMASSHHNHHSHHHPHHHHGHYGSRNPPPPGGSNLEKWYYSTINHTSAPGGTPPLASLGSEGYKLLAGLLEYDPSKRLTAAQALQSPFFSTGDRVSANCFEGCKNEYPCRRVSQDDNDIRTSSLPGTKRSGLPDDSLIRPAKRQKE
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).  Required for normal growth and secondary metabolism.
What are the official names of this protein?
Serine/threonine-protein kinase SSN3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSP_SCHPO
Sequence: MFDSFMKRNQLALIMFRACSKLQYHGVNTSLSRHLFLAKRNLSISSACLEAKNSQKFPALDTFEPRHIGPSKTDQQYQLESLGYKDFDSFLKDVIPDSVRTPESQLMAFGSVNPNEKNPPVNYSESEFTTLANNVANQNKLIKSFIGMGYYNVKLPAAIQRNVLENPEWYTQYTPYQAEISQGRLESMMNYQTMIADLTGLSISNASLLDEGTAAGEAMVMLMANDKKKRKTFLVDKNIYPNTLSVLRTRASGFGIKIELDNITPELITKSAKHVFGIFVQYPAADGSIFDYGHLAATARSFNMHVVAATDLLALTILKSPGEWGADVAVGSTQRFGLPMGYGGPHAGFFACSEEFKRKIPGRLIGLSKDRLENPAYRLALQTREQHIRREKATSNICTAQALLANMSAFYAIYHGPNGLQEIANRIYASTSFLKSALESSGYKIVNKSHFFDTLTIEVESADKVLAKALDHGYNLRKVDDSHVGLSLDETVCDKDIQALFSIFNINKSVDQYYMEIATSEPNGNSASTVDNLSICSLPENFRRTTLYLQHPVFNRYHSETELMRYIHHLQSKDLSLAHAMTPLGSCTMKLNAVTEMMPITNPLFANIHPYVPEEQAKGYRHVIEDLQLMLTTITGFDAACFQPNSGAAGEYTGLSVIRAYQRSIGQGHRNICLIPVSAHGTNPASAAMAGFTVIPVKCLNNGYLDMQDLKEKASKHADKLAAFMVTYPSTFGIFEPDVKEALEVIHEHGGQVYFDGANMNAMVGLCKAGDIGADVCHLNLHKTFCIPHGGGGPGVGPICVKKHLADFLPSHPVVSCGGKNGITSVSSSPFGSAGILPISWAYMRMMGLAGLRDASKAALLNANYMAKRLSSHYKLVYTNKNNLCAHEFILDAREFKATAGVDATDIAKRLQDYSFHAPTLSWPIANTLMIEPTESESMYEMDRFCDALISIRQEIREIEEGLQPKDNNLLVNAPHPQKDIASEKWDRPYTRERAVYPVPLLKERKFWPSVARLDDAYGDKNLFCTCSPVV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Putative glycine dehydrogenase (decarboxylating), mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSB_PSECP
Sequence: MQESTANKVAANATSSFTEHLQRDRPELLPFNRSGQGSATAAAPLQVPHATTIVAMSYNGGVLMAGDRRATMGNVIASRHIEKVFPADRYSVLGIAGTAGIAIDLTRLFQVELEHYEKIEGTLLSLEGKANRLGAMIRGNLPLAMQGLAVVPLFAGFDTSAGVGRLFSYDVTGGRYEEHEHHTVGSGSVFARGALKKLWRPNLSAEEAVAVAIEALFDAADDDSATGGPDTVRKLWPVVYTVDSTGTRRVAEPQLAAASQHVIEARTIAGREA
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_STAA1
Sequence: MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMRGEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSENNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALASPNNILGISYLKAIAKNAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDIQHLYVTPHITLNQIFPYLKYQIIAMTTDSLKNIYTVTEGFENRLKSNIYEATDFHHFVKLLKTKRYTYTHIQRLLMNVLLNIKPTDVTSNIHAVKVLAMNDRGRQYLKHLKTAFPERQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_HUPLU
Sequence: MIQPQTYLNVADNSGAKKPMCIRILKASNRKYANTGNVIVAVVKEAVPNMPLRKSEIVRAVVVRTCKELKRNNGMIIQFDDNAAVIINQEGNPRGTRVFGPVARESREFNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATP8_VANPO
Sequence: MPQLIPFYFLNQLTYGFLLMTILLVLFSQFFLPMILRLYLTRLFISKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: CH60_METMA
Sequence: MASKQIMFDESARKALLSGVDKVANTVKITLGPKGRYVVLDKSTKPVVTNDGVTIAKEIELHDKFENMGAKLVKEVASKTQDNTGDGTTTATLLAQSMIREGLKNISAGANPIEVKKGIEIATEKVVGYLKGKSVEVKGKDKIIQVATISANNDEEIGNLIADAMERVGYNGVITVEDSKTMETSLDVVEGMQFDRGFVSPYMALDTEKMVCEFEDPYILITDKKINSMKQIVPVLEKVASEGRSLLIIAEDVDGDAQAALILNIIRGALRVCAVKAPGFGNERKEMLEDIAVLTGGQVISEEKGMKLEEFSDYMLGNARKVTVDNHKTIIVEGRGDKADIDERVRVIEAQINIAEADYRKTELKKRMAKLGGGVAVIKVGAATETELKEKKMRIDDALNATKAAVEEGVVTGGGISLFRAAATLDSLDLDGDRQIGVKIVQRAIEDPVRQIAANAGREGAEVVAAIKAESSEHFGYNAKTDVFEDLFEAGVIDPTKVVRSGLQNAASIAGMVLTTEALVTDFDEEKDERTAAIII
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI1_VIBPA
Sequence: MKPINTFFSSFLLALTLGLPATSQAEVEIPIMDLVDVRGIRENQLVGYGLVVGLAGQGDRNQVKFTSQSITNMLRQFGVQIDDSMDPKLRNVASVSVTASVDPMAGPGQTLDVVVSSIGDAKSLRGGTLLLTPLRGIDGEVYAIAQGSVVVGGLSAEGKSGSKVEVNTPTAGRVPNGATLEREIKTDFNQRDEITLNLRKPSFTTAKNIAREINNTFGPNVAVAINKARVDMRAPKDTQQRVIMMSMLEEMSVVEGRKPARIVFNSRTGTVVIGKNVKVGEAAVSHGNLTVRISESEKVSQPNAFADGETKVVNQTDIDVNEELAQMVIWPPGTELNTIVDAVNSLGATPTDLMSILQALNEAGALNAELVVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein 1, Basal body P-ring protein 1.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: TIPM_BPN15
Sequence: MTIETFSWGIKVSSQPTEGSKDTVRKIQFGDGYAQVSGSGLNDEIRTYEFSFSGDPITANEIHAFLRRHKVKSFIFTPPFGDTALWRVEADTLKKVVKNVKVITVTATFEQAFAP
What is the function of this protein?
Part of the distal tail tip which plays a role in DNA ejection during entry, and in tail assembly initiation during exit.  May bind tail tip complex associated with tape measure protein and allow tail tube protein polymerization on top of tail tip.
What are the official names of this protein?
Tail tip protein M, Gene product 17, gp17.
What is the protein family that this protein belongs to?
Belongs to the lambda-like tail tip protein M family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: VF424_ASFK5
Sequence: MSNYYYYYGGGRYDWLKTVEPTNFLKIGLPYQAHPLHLQHQATTPPSILEKFKRADILLNEVKSEMDPLMLQPETEKKLYQVLGSIDMFKGLRKKVEYTYNAQIVTNAWLKMYELLNTMNFNNTSQAFCNCELPGGFISAINHFNHTMMHYPTFNWVASSLYPSSETDALEDHYGLYQCNPDNWLMQSPLLKKNMDYNNGDVTIASNVKNLALKATQKLTPIHLYTADGGINVGHDYNKQEELNLKLHFGQALTGLLSLSKGGNMILKHYTLNHAFTLSLICVFSHFFEELYITKPTSSRPSNSETYIVGKNRLRLFTPKEEQVLLKRLEFFNDTPLVDLSLYQNLLESIYFAVETIHLKQQIEFLNFGMKCYRHFYNKIKLLNEYLAPKKKIFQDRWRVLNKLYVLEKKHKLKLCTSFQGSVA
What are the official names of this protein?
Probable methyltransferase EP424R, pEP424R.
What are the subcellular locations of this protein?
Virion.
Protein: LEPA_MYCPU
Sequence: MNKSKIRNFSIIAHIDHGKSTLADRILEITQTVSTRELKAQHLDSMDLEQERGITIKLNAVQIKYKDYIFHLIDTPGHVDFTYEVSRSLAASEGALLLVDATQGIEAQTLANAYLALENNLKIIPIINKIDLPSADPERIKGEIEEVIGISAKDTILISAKSGLNVEKVLEEIVDKISYPIDADDDKPLKALVFDSYFDAYRGVILLVRIFEGKIAVNDQFKFISTNKQFHVIELGVRTPTEVKKPFLESGEVGWIAASIRDAKDVSVGDTLTLVKNPTKEALPGYKKVKAVVFTGFYPIDGKDYPVLKESLEKISLSDSSITWELESSKALGFGFRVGFLGMLHMEVLQERLKREFNIDIIATAPSVEYKVYLTNNKVEIVSNPSDLPDRNYIKNIKEPFIRSFILVTEEFIGGIMELCQSKRGVYVNIEYIDKRVKIIYELPLSEIILDFFDKLKSISKGYASFDYEFIEYRDADLVKVDILLNKEKVDAFSFISHRENAYERSKELALKLKDVIPKQSFEIPIQAIIGAKVIARETIKAYRKDVTAKLYGGDVTRRQKLLKKQKEGKKRMKSIGSVEVPQEAFLSVLKSNMDKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TSAS2_HUMAN
Sequence: MGNPRLPRLLCALKFSGFLSNIRGPLAGEDGMGDTQLARVRDSALKTPWRPAPCPPPAHSLDDWK
What are the official names of this protein?
Putative uncharacterized protein TSPEAR-AS2, TSPEAR antisense RNA 2, TSPEAR antisense gene protein 2.
Protein: ISPG_RUMCH
Sequence: MEDCIKRNQTKKIKVGDIFIGGDSPISVQSMTNTDTRDVKATIHQIKSLEEAGCDIVRLAILDNEAATAIGEIKKHVKIPLVADIHYDYRLAVECMKNGVDKIRLNPGNIGGNDRVRTVAGMAKERGIPIRIGVNSGSVEKRILEKFGGVTAEGMVESALAHVAMLENVDFNDIAISIKASSVPMTIAAYRLLSEKCLYPLHVGVTEAGTVYKGTIKSAVGIGCLLAEGIGDTIRVSLTGDPVEEIKVGKQILKSLDLLKEGIEIVSCPTCGRTQVNLIDIANSIEPLLEKLNKNIKVAIMGCAVNGPGEAKDADIGIAGGVNEVLLFKKGRIIRKIPQENVVEELIKEISEM
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: DAD1_MESAU
Sequence: MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NUP58_MOUSE
Sequence: MATGFSFGSGTLGSTTVAPGGTGAGSGFSFGTVASSTPSVGLNFGSLGSSVTPASTSASAGGFGTGLFGSKPATGFTLGGTSAGTAATTSASTTGFSLGFSKPAASATPFALPVTSTSASGLTLSSALTSTPAASTGFTLNNLGATPATTTTASTGLSLGGALAGLGGSLFQSGNTATSGLGQNALSLSLGTTAPTSAASNEGLGGIDFSTSSDKKSDKTGTRPEDSKALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAASGLQRNTLNIDKLKLETAQELKNAEIALRTQKTPPGLQHENTAPADYFRILVQQFEVQLQQYRQQIEELENHLATQASNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLGYRKMFLGDAVDVFEARRTEAKKWQNAPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCGTTGASTFGFGTTDKPSGSLSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGGQLLQLKRPPAGNKRGKR
What is the function of this protein?
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
What are the official names of this protein?
Nucleoporin p58/p45, 58 kDa nucleoporin, Nucleoporin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUP58 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter.
Protein: LIPL_BACAN
Sequence: MSNSRSILSQPEWRIVDQSSLGPTFHALQSFAMDDTLCTSIGKGESAATMRSWVHHNTIVLGIQDSRLPHLEEGISFLKENNFNVIVRNSGGLAVVLDEGVLNVSLLFQETEKGIDIDLGYDTMWHLIQEMLKDYDVTIEAKEIVGSYCPGSYDLSIRDQKFAGISQRRIRGGVAVQIYLCATGSGSERAALVRDFYNLAIQGEETRFTYPEIVPSTMASLSELLDETITVQDLMMRLLKTLQQFAPKLTPSQLTIDEIPLYETNLQRIIDRNNKALGLEK
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: DRE2_TALSN
Sequence: MPSLPVLIDTTTEFDVSSPQNVTQKRSLLLAPPSIAAHEEKLRDIFTTFDRSVTDLQMLDRLSAGFVTLPASTYDLVLVLTDTNGARRNEALELLTRDIFNILTPSMKPSAQLQLQDGPFQANEGREAILAGLVEKHGAFEKPQYQEAAVPLRFGANKRKNKISPEPVKIESVGFVDNYDDDELINEDDLLDEEDLGKPVQQPAECQPETAKKRRRACKDCTCGLAAQLEAEDAERREKANADLNVLKLKTDELNDEVDFTVQGKTGSCNSCSLGDAFRCASCPFIGLPAFKPGEEVRIMNDMAQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35.  Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18.  Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.
What are the official names of this protein?
Fe-S cluster assembly protein dre2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: LACC_STAAB
Sequence: MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDLAGIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGVEWIIVSLGAQGAFAKHNHTFYRVNIPTISVLNPVGSGDSTVAGITSAILNHENDLDLLKKANTLGMLNAQEAQTGYVNLNNYDDLFNQIEVLEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: RPPH_XANCB
Sequence: MIDPDGFRPNVGIVLMREDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLPSRAVRRNERQVCIGQKQVWFLLQFTGQESHLKLDHTDSPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPLAQTVAGPAAVGVMPQRALEAWLPGSSAAGHDRPRKRPRKRGGVLPVRINND
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.