PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_OCEIH
Sequence: MKEKFELVSAYDPAGDQPNAINEITKKVLAGQRHQTLLGATGTGKTFTMSNVVKEINRPTLVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDKLRHSATSALFERQDVLIVASVSCIYGLGNPEEYKSQVLSLRMGMEKDRDQLLRDLVEVQYARNDINFQRGTFRVRGDSVEIIPASHEEYCIRVEFFGDEIDRIREVDALTGEIIGDREHVAIFPASHFVTREEKMKIAIQNIEKELEEQLKEMRDNGKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSRHLTLRGPGAVPYTLLDFFPEDFLVIIDESHVTLPQIRGMFNGDQARKQVLVDHGFRLPSAMDNRPLRFQEFEDKTKQLVYVSATPGPYELEHSPEMTEQIIRPTGLLDPKVEVRPIEGQIDNLIEEIRIRMEKNERVLITTLTKKMSEDLTDYLKEIGMKVAYLHSEIKTLERIEVIRDLRVGKFDVLVGINLLREGLDIPEVSLVSILDADKEGFLRSERSLIQTMGRAARNENGKVIMYADKMTDSMKKAIDETNRRRTIQTEYNEQHGITPKTIRKEVRDVIKATTAAEETESYEPKTKQINKMTKKEREKVIEQMENEMKQAAKDLDFEKAAELRDVILELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_SALPB
Sequence: MPSLSKEAALVHDALVARGLETPLRPPMDELDNETRKSLIAGHMTEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFAGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILTALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHP
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PRR32_MOUSE
Sequence: MACTENGLAGHSHSPIIVPVDKNRSKETCHNVQLRSLSSMLKDDEDDADVWTRPPVSLRPPFNVPRTGARIPQNPRAPRHPLTLTPAIEEESLATAEINSSEGLESQSQKGHDSINMSQEFSGSPMALMIGGPRVGSRVLERSGNNSKPYIPVPRSQGFFPPRGSQSRGPPYIPTLRSGIMMEVTPGNARMANRGNMAHVSFPLGSPRHPMDNWQQSPSLPLSPSITGLPCSSAHCFLPPQAPAFNPFPVMPTAFASPLRFGPPLLPYVFHYNTGAMYPPPYLN
What are the official names of this protein?
Proline-rich protein 32.
Protein: RSUA_ECO57
Sequence: MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPEHDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLDIDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDLTKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGEYRPLTEEEIASVV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
What are the official names of this protein?
Ribosomal small subunit pseudouridine synthase A, 16S pseudouridylate 516 synthase, 16S rRNA pseudouridine(516) synthase, rRNA pseudouridylate synthase A, rRNA-uridine isomerase A.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: Y2730_DESHY
Sequence: MDIKLINIGFGNIVSANRIISIVSPESAPIKRIIQEARDAGMLIDATYGRRTRAVIICDSHHVILSAVQPETVAHRLSAKEASNTAEDPAD
What are the official names of this protein?
Putative regulatory protein DSY2730.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: ENO_COXB1
Sequence: MTATITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGKGVLQAVENVNGPIRDALLGQDPRSQEEIDRIMIELDGTENKANLGANAILGVSLAVAYAAANNADLPLYRYLGGDGGPFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAEALRYGAEVFHALKKRLVSRGLMSAVGDEGGFAPDLPNNEAAFELILEAIEDANYVPGKDIYLALDAASSELYQNGRYDFENNQLTSEEMIDRLTEWTKKYPVISIEDGLSENDWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLATVGLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIERELNDQAPYAGKEAFLFNRK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL16_CYTH3
Sequence: MLQPKRTKYRKQQKGRVTGVATRGHRIAFGSFAIKSLEGGWITARQIEAARIAMTRAMKREGQVWIRVFPDKPITQKPAEVRMGKGKGAPEYWVACIKPGTILFESGGVSIETAQESLRLAAQKLPFKTKFIVRPDYVAS
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL30_METCA
Sequence: MTVKTLRVTQVRSANGRLETHKACLRGLGLRKPHHTVEVRGTPEILGMISKVSYLLKVEEI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NQRB_HAEDU
Sequence: MGLKNLFEKMEPAFHKGGKYEKWYTLFEATYTILYTPGTVTKKDSHVRDALDSKRMMILVWLALFPAMFWGMYNVGGQAILATSHLGSLTDSIANNWHYAFSEAVGATLTADAGWGSKMLLGATYFLPIYLTIFLVGGFWEVVFAMVRKHEINEGFFVTSILLALIVPPTLPLWQAALAATFGVVVAKEVFGGVGKNFMNPALAGRAFLFFAYPAQISGDLVWTAADGFSGATALSQWAQGGQIALKHAVTGQEITWMDAFLGNIPGSIGEVSTLMLMIGAAIIVFARIASWRIIAGVLVGMAATATLFNLIGSETNLLFAMPWYWHLVLGGFALGMFFMATDPVSASFTNKGKWWYGALIGVMCVVIRVANPAYPEGMMLAILFANLFAPIFDYLVVQSNIKRRKAKAA
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_PHEZH
Sequence: MPSRPPLTVLLASPRGFCAGVDRAIQIVERAIEKYGAPVYVRHEIVHNRHVVERLKALGAVFVEELDQAPDDRPVVFSAHGVPKSVPAAAKSRRMLYLDATCPLVSKVHVEAQRHFDAGREIVLIGHAGHPEVVGTMGQLPEGAVALIETVADAMAFQPRDPANVAFVTQTTLSVDDTAEIVEALRARFPAIAAPHKEDICYATTNRQEAVKAIAAKAQVLVVLGSANSSNSVRLAEVGRRAGARAYLIDDAEGLDFTWLEGVETVGVTAGASAPEVLVQGVLDRLAERFEVTLTEADTARETVTFKLPRALAG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MTX1_DROME
Sequence: MEMQLGAMLYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKRVLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACDVVQVMAGFDVNDKLDKHEGDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLTKTPSGTEASLTASERKFLDSELNTKIVAGVGAVLAMGAFAAWRGIYNQLTTRSSTDYDGIDYEDDEMEEGLD
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.  Essential for embryonic development (By similarity).
What are the official names of this protein?
Metaxin-1 homolog, Mitochondrial outer membrane import complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: NDUS3_RECAM
Sequence: MKKQEQNQFLKEFGISLIKMFPKYIDKAIYSKGELTLHVKPTNLIALMKILKNHTNCQFKSLSDLCAVDFPEKKERFEIVYNLLSVRYNSRIRVKTFVDELTPVPSVTCLFQAAGWFEREVWDLFGVYFTNHPDLRRILTDYGFEGHPMRKDFPLTGYVEVRYDDEQKRVVTESLEMTQEFRSFNFTSPWEQIEISKPNIKEKK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase subunit 9.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Matrix and cytoplasmic side of the mitochondrial inner membrane.
Protein: MGLA1_PHOPR
Sequence: MNQVLLEMRGITKTFPGVKALDNVQLTLKKGRVMALMGENGAGKSTLMKVLFGIYQRDCGTIRYQGEQVNYSGAKEALEAGVSMIHQELSPILHRSIAENIWLGREPLKGPLRLIDHAKMYRDTTELLKKLDLHLDPRTPMSELTVATMQMIEISKAISYNSKIIIMDEPTSALTGKEVDHLFEIIEKLKKQGVSIVYISHKMDEIFRICDDITVFRDGCYIGEREAQNTNHDELVQMMVGRDLGDVFPPPTAKPGKVRLEVKNLSVEGVFDNISFKLHEGEILGIAGLVGAGRTELIETLFGVRKHDVGEIWINGENVEIKTPQDAISHKMAFLTEDRRQSGLYLMLDIFANTSIAHLDAYRNKVVNVLDVRSMQKDCASQCTKLKVKTPGMAEKIDNLSGGNQQKVLLARWMLTKPDILFLDEPTRGIDIGAKSEIYKLMRLLTGMGKSLVMISSELPEVIGMSDRILVMHGGKLKGELDGKDASQQQVMSMAFN
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VPS36_SCHPO
Sequence: MAFYLETTPSNLPVLDPSEEILLVQDQVGLYFGDEKSFRHNNGTLYLTKKHIFYVDSVDPKKNSLKIKISDIRDVQHTSRYFRSSPKIRLSLRHVEKSWACKICTFINVGDPINPCRNCGVANRFTIIKPKSDARFSQGLCTACTFQNYPDLNTCEICGNQLKNVDRNQLIQLSFRGSGSSKFYEAIKSETDEIEKQRYSNKYDTKVLRKAILEKSLRMGGIHDLEQSHEMQLAKNGRTLVHAFQDLDAFFSLAKDTMSLADQFAEKMDGLTGTQQSDKVQQLLNKSNQLGVLRGNHLDNVPVSANSRLYDIELCKSISEVLRTRLKADTDTVTMTQAWAIYNRSRKANLIPPTRFVKACELIDSMEVGITTSKMNSGLILFQLKTSNHSGKLLSAILEVMNPSTTALKCAMRLHWSIGVTLERLYQAEMDGYIVRDVYEESGSSLLYWKNEFDELSEELTKWFDES
What is the function of this protein?
Component of the ESCRT-II complex, which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.  Its ability to bind ubiquitin plays a central role in endosomal sorting of ubiquitinated cargo proteins by the ESCRT complexes (By similarity).  Required for vacuolar sorting of carboxypeptidase S (CPS).
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 36.
What is the protein family that this protein belongs to?
Belongs to the VPS36 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: SYR_LAWIP
Sequence: MRAEQYLKTCLECTIKKLGYTWPKKAVIEIPQNTLHGDLATNIALVLANNIGINPKNIAEKIAEKLQQESTSFSSVSVAGPGFLNITFSPTFWQKTINHILSKGSSYGSCQLGNKQKVLIEYVSANPTGPLHIGHGRGAAIGDTLARLLRFTGYNVTTEYYINDAGRQMQLLGLSIWLRIKELSGIQVTWPEEYYKGTYIIEIAKALLEEQPDIISYTDIDGEQASFHFGMNVILNGIKQDLKTFKVEHEEWFSERTLIKTNAIEQTLKALECTGLTFEKEGALWFQSTVFGDDKDRVLRKSDKSLTYFALDIAYHYTKYNRGFDRIIDILGADHHGYIARIKAAMQAFGHDPMTFDIILIQLVSLLENGIQVAMSTRAGQFEKLIDVINEVGVDAARFMFLLRKSDAHLDFDLELVKQRTMNNPVYYVQYAYARICSIIRKAHDLGFTITDVNEVPLSNITTKDELNLLRLLDKFEDVIYNAAQHLAPHYITHYLMELAGELHSYYAKYPVLQSNEKTIVLSRLALLQAVGQVIYNALNILGVTAPKNM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CLOAB
Sequence: MCKDIKILAIESSCDETAAAVVVNGRKVLSNIISSQIDIHKKFGGVVPEIASRKHIENISLVVQDAIKEAGVELKDIDAVGVTYGPGLVGALLVGLQYAKGLAYSINKPLIGVNHIEGHISANFIQYPDLKPPFACLVVSGGHTFIVYMKDYGEFEVLGQTRDDAAGEAFDKIARAIGLGYPGGPKIQEMAKRGDESALQFPRAKFHDNSLDFSFSGVKSAVLNYLNTMKMQEKEINRADVAASFQKNVVDFLVDNTIKACKIKKIDRIAVAGGVASNSFLRETMVSRGRENGIDVLFPAPILCTDNAAMIGSAAYFEFKKGNIAPLDLNAIPNLKLGER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CHLL2
Sequence: MIQKETNLVVADNSGAKKVRCIHVFGGTGRRYAGLGDQVIVSVKAAVPGGVVKKKDVCKAVVVRCAKEQRRKDGSYIRFDENAVVLLNAQGEPRGTRIFGPVARELRDRKYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RIMP_HYPNA
Sequence: MIVLTEQERRLLSLVQPVAEGLGMEIVRLRVQGGRRPHLQIMAERAGGAPTGIEDCARLSRGMSPVLEAADPISEAYTLEVSTPGIDRPLTRPGDFARWIGHAVRIELARPIDGRRRFTGTITGEDNDGAHIELDDETKLVAAVHEMSRASLVLTDELIEAARVAGNLPPQPEDDEDMLADFEIDESEDEEDPETGDVQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_NOSS1
Sequence: MIETNVSRRHHETFIQVIQSYYQLTKPRIIPLLLITTAGSMWIAAQGQVDPVLLLVTMAGGTLAAASAQTINCIYDRDIDYEMERTRHRPMPSGKVQVRDALIFAIALAVLSFTLLTVFANLLAASLALSGIIFYVLIYTHWLKRHSTQNIVIGGAAGAIPALVGWAAVTGTLSWSAWLIFAIVFLWTPPHFWALALMIRDDYAKVGIPMLPVVEGNAATVKQIWYYTLITVAATLLLVYPLHASGIVYAAIAISLGAVFIRKSWRLLHNPEDRPTARELFLYSISYMMLLCLGMVVDSLPLTHHLVNAAINQLHLIS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSRA_LEPBL
Sequence: MLVLARRTNESIMIGDDIEIVIVDIKGDQVKIGVKAPRNVSVHRAEVYKDIQEENRKAAETKIKPEDLGKIGDILKKKDSGKKG
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CAMLR
Sequence: MKKEIHPEYVECKVSCACGNSFTTKSNKPEIKVDICSSCHPFFTGSEKIVDAAGRVEKFKKKYAMQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: CWC27_CRYNJ
Sequence: MSNLYATEPATNGKVIIDTTAGEIEVELWGKECPKAVRNFLALTMEGYYDGVIFHRVVPGFIIQSGDPTGTGMGGESFYGEPFEDEIHGRLKFNRRGLLGMANNGSRNSNTSQFFITLDAAPELTNKHTMFGKIVGNTIFNVLNIGNLDTDKEERPLIPPKIRRIHIIENPFDDIVPRITAEEKKAQQKAKLEAKKDMEQRERRAKAKKNTGLLSFGDSEEIPEEEVTVKKKSMTRQDLVDPSEAEHTKSKTSKMTETFVNIPPSLKDLGKSRENEASEEKKAVDLKNIRAQHEREKAGGSAARQAEIKRMEEDLRRLKKRSGSVSDSESDSSSRARRKGPSYLEQELAKYASKRGRAAMKAGNKRGRRDEEEDVLTEMRKFSKRVMQAGDEPEEEQAEEIEEGEAKEEGTGIGAAMAEEEGGIEVDDDVGWLTHKLKFQVDDKELTRRAEDEYAVIDPRAKARDLLGKPDKKKLKGNPNRRTVRNSGRNR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Peptidyl-prolyl isomerase CWC27, PPIase CWC27, Rotamase CWC27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FABZ_THEMA
Sequence: MNIDYVKSILPHRYPFLLVDGVIEESEDRIVAFKNISISDPVFQGHFPEYPIYPGVLIVEGLAQTAGILLLKSVEGIPLFLGIDEARFKKEVRPGDRLIYEVRKLGEKLGTVQVEGVAKVDDKIVAKARLLLGVKKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_MYCTO
Sequence: MTSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRVTRETLALLIDLARTAHLEERRDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVTDVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSRHFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFHIIDRHFATAPLESNAPVLLGLIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFAQPLDDLPTAEGTGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPSVLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDGLVRRYRTERGRAG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT1_ANSCY
Sequence: MVSESHHEALAAPPATTVAAAPPSNVTEPASPGGGGGKEDAFSKLKEKFMNELNKIPLPPWALIAIAIVAVLLILTCCFCLCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQDDDAETGLTDGEEKEEPKEVEKLGKIQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEYKVAMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQPEEEVDAMLAVKK
What is the function of this protein?
Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity).  May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse.  It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.  May play a role in dendrite formation by melanocytes (By similarity).  May play a role in regulating the secretion of hormones relevant to the reproduction and egg-laying of female geese (PubMed:25146222).
What are the official names of this protein?
Synaptotagmin-1, Synaptotagmin I, SytI.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm. Note=Synaptic vesicles and chromaffin granules.
Protein: HIS7_LACPL
Sequence: MRQATIKRETKETQIEISLNLDEQSGIEIDTGIGFLNHMLNLFAKHGRFGLVVKCHGDLDVDPHHTTEDTGIVLGECFKQALGDKQGIERYGTEFVPMDETLGQVSVDLSGRSYLVFDAELTNPRLGGLDTETVEDFFQAVAFAAEMNLHARILYGRNTHHKVESLFKAFGRAMRAAVTINPDIQGVNSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFIT1_MOUSE
Sequence: MGENADGDQVMENLLQLRCHFTWKLLFENNDIPDLEVRISEQVQFLDIKNPLGMHNLLAYVRHLKGQQDEALQSLKEAEALIQSEQLSKRSLATWGNCAWLHYHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMACFAKALKVEPENPEYNTGYAVVAYRQDLDDNFISLEPLRKAVRLNPEDPYLKVLLALKLQDLGEHVEAEAHIEEALSSTSCQSYVIRYAAKYFRRKHRVDKALHLLNRALQASPSSGYLHYQKGLCYKQQISQLRTSRNRQPRRQDNVQELAQQAIHEFQETLKLRPTFEMAYVCMAEVQAEIHQYEEAERNFQKALNNKTLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYLKGLKVEEKSFAWRKLLTALEKVAERRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYEKALRLTGEMNPAF
What is the function of this protein?
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs.  Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection.  Directly binds PPP-RNA in a non-sequence-specific manner.  Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism).
What are the official names of this protein?
Interferon-induced protein with tetratricopeptide repeats 1, IFIT-1, Glucocorticoid-attenuated response gene 16 protein, GARG-16, Interferon-induced 56 kDa protein, IFI-56K, P56.
What is the protein family that this protein belongs to?
Belongs to the IFIT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_ANAMM
Sequence: MSRADTIFALSTPMGKSGVAVIRVSGHDALKSMQLLGVKEPVRSRVATCKTLYDKKRQPIDQAVVLYFPGPGSFTGEDVVELQVHGSLAVIRLLFEELQTVFRIAEPGEFSLRAFLNGKIDLTRAEGIADLVNSETEAQLRQAFAQSSGFLERLYEEWRSSLVDILSDLEAYIDFPDDVSPQILRSVHDRVKELHNSLERHLDDGHRGERLRHGMRVAILGKPNVGKSTLFNHLARRDMAIVSEYPGTTRDVLEAHVDIGGYPFIVVDTAGIRESTDFVEREGIMRAKSEAATADIRIMLFPHSEAGNLGVHEAIEGGDDGKTIYVLSKADSAKEGETRIIEGKQFYLVSVHTNLGVDSLLSALKERAIDGFPKSGDVLITSQRHRGHLQSAAKVISDITDEMPAEIVAEYLRLATKEIGKVTGAVYGDDILDNIFKRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.