PharMolix/UniProtQA huggingface dataset:
Protein: CIDA_STAA1
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNP4_THEVO
Sequence: MSNNNYERLITKKDVYRVANERLYYLFSLAFQTGDERYIDLMERIGRRMDITLPQDIKRMYCKKCKKPYKNVRVRLKKNVITVTCLECGDIRRFQINR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABIL4_ORYSJ
Sequence: MQPLRPSPAAGGWAGVAGVGPTTVDEASMERSKSFVKALQELKNLRPQLYSASEYCEKSYLHSEQKQMVLENLKDYAVRAVVNAVDHLGTVAYKLTDLFEQQASEVSTVELKVARLNQQILTCQIFTDRAGLRQQKIGGTTFKHHKHYILPSTGHKRTQAARLQTDNGQDSKPKPYPSAKTLSWHLSSENSISTTGAQKYTFTLGDTISSKPASNGSMYLLGKDIPASPMHKPLQPNGNTSFDAKKNVGSKDQPGFMHMSTFNALDKPRGREIQKVPVSTKSMLATLFIKHKSAKTRKASVR
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
Probable protein ABIL4, Abl interactor-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LEPA_FRATH
Sequence: MKNIRNFSIIAHIDHGKSTLSDRFIQVCNGLSEREMKEQVLDSMDIERERGITIKAQSVTLDYTARDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQTVANCYTAIEQNLEVIPILNKIDLPFAEPDRVAQEIEEIIGIDATGATTCSAKIGIGVEDVLETIVAKVPAPEGDVNAKLQALIIDSWFDNYLGVVSLVRVKNGTIKKGEKFKVMSTGVAYQVDRLGVFTPKMKDLDHLKAGEVGFIVAGIKDIHGAPVGDTLTHAHNPTDKPVPGFKKVQPQVYAGMFTISSDDYPDFREALEKLSLNDASLFFEPEVSQALGFGFRCGFLGMLHMEIIQERLEREYNLDLITSAPTVVYKAIKKDGEIIEVDNLSKLPEPGAIAEIQEPIVRANILVPKDYVGSVITICIEKRGVQVDLNYVGNQVSITYDLPMIEVVSDFFDTLKSVTKGYGSLDYELIRYEPANMVCLDVLINGDKVDALASIVHKDQAKYKGRELVERLKELIPRQMFEVAIQAAIGGTIVARSTVKALRKNVLAKCYGGDVSRKKKLLEKQKEGKKRMKNIGSVEIPQEAFLSVLKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MTSB_STRGN
Sequence: MIQEFIQGLHDFHFLQNALITAIVIGVVAGAVGCFIILRGMSLMGDAISHAVLPGVALSFILGINFFIGAITFGLLASIIITYIKGNSIIKSDTAIGITFSSFLALGIILISVAKSSTDLFHILFGNILAVQDLDMWISIGVGILVLLVISIFFKQLLLTSFDPLLAQAMGMKVNFYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYAKSLKTMILLSSALGAGASVLGLFIGYSFNVAAGSSIVLTSALIFLVSFFIAPKQRYLKRKVK
What is the function of this protein?
Part of the high-affinity ABC transporter complex ScaABC involved in manganese import.  Probably responsible for the translocation of the substrate across the membrane.  Essential for growth under Mn(2+)-limiting conditions.
What are the official names of this protein?
Manganese import system permease protein ScaB, ORF2.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GGGPS_METB6
Sequence: MKWKDWVHVTKLDPDKQLGPGDIDAIAASGTDALMLSGTLNVTKENLLALQKMIAQYDLPLVMEPAGPEAVLMEGIEYVFVPSVLNTTDVQWIVGKHRSWVQQQDGKIPWDMVVPEAYIVLNPASSVGRVTKAVCDLKPAEVAAYTEVADRYFHFPIVYIEYSGTYGAPAVVKAAAEAIDHAILYYGGGINSAEKAAEMGKYADTIVVGNAVYDQGASVLKATVDAVQ
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AH1_PRUSE
Sequence: AKTDPPIHCASLXRSS
What are the official names of this protein?
Amygdalin beta-glucosidase 1, Amygdalin beta-glucosidase I, Amygdalin hydrolase isozyme I, AH I.
Protein: GLYA_NOCFA
Sequence: MTQTTASVNTQSLGELDPELAAAMAGELARERDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGGCENVDVVENLARERAKELFGAEFANVQPHSGAQANAAVLMSLMDPGDRLLGLDLAHGGHLTHGMRLNFSGKLYEVHSYGVSKEDHRVDMDEVRTIALGAKPKVIVAGWSAYPRHQDFAAFRAIADEVGAYLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGLILAKQEFAKKINSAVFPGQQGGPLMHAIAAKAVAFKIAGTEEFRDRQQRTLSGAKILAERLTGADVADKGISVLTGGTDVHLVLVDLRNSQLDGQQGEDLLHEIGITVNRNAVPFDPRPPMVTSGLRIGTAALATRGFGDAEFTEVADIIATALAGGSDAETLRGRVRALAQRVPLYQGLEDWHLLG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CS3HD_THETK
Sequence: MSCCAYFRGRDCLQTYEDHITQALEACERLRPYYGRWMEKAFGTADAAALAVEFHDLGKLAKAYIAGNRARYRHEVLGAYFALKTLQTEARYYVAAAVALHHEPMILAAYAGELGERAIHVSTLRAMLKDSDLSLGCTPNYSYRPEVAAALREWASRPPTADDVADAFQELAVYLSGGAPEEARVKRLRVAGLLHVLTVCDNWGARGRPGEGTFISRYMTVSELGL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity.  Acts as a ssDNA and ssRNA nuclease, probably with both exo- and endonuclease activities.  Activity is higher for DNA than RNA (By similarity).
What are the official names of this protein?
CRISPR-associated endonuclease Cas3-HD, CRISPR-associated ssDNA/ssRNA endonuclease Cas3-HD.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated nuclease Cas3-HD family.
Protein: Y073_MYCTU
Sequence: MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGSLVMLLGPSGCGKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRRNKVGIVFQAFNLVPSLTAVENVMVPLRSAGMSRRASRRRAEELLARVNLAERMNHRPGDLSGGQQQRVAVARAIALDPPLILADEPTAHLDFIQVEEVLRLIRELADGERVVVVATHDSRMLPMADRVVELTPDFAETNRPPETVHLQAGEVLFEQSTMGDLIYVVSEGEFEIVHELADGGEELVKVAGPGDYFGEIGVLFHLPRSATVRARSDATAVGYTVQAFRERLGVGGLRDLIEHRALAND
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Rv0073.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: GLGC_ALBFT
Sequence: MKDGAHHRPVRRTISLVLAGGRGSRLQDLTENCAKPAVHFGGKFRIIDFVLSNCVNSGLHRIGVLTQYKSHSLLRHLQHGWSFLRNEVNEFIDLLPAQQRVDEASWYRGTADAVYQNIDILREHDPKYILVLAGDHVYKMNYASLIEDHVALGAPCTVACIEVPLAEASAFGVMTVDAMRHITRFDEKPAHPQPMLDQPEQALVSMGVYVFDADYLFAALQTDIEDAASHHDFGKDLIPAIVSRGEAMAHPFDLSCVKSSPESPSYWRDVGTVDAYWAANIDLTATIPQLDLYDKDWPIWTYQPTSPPAKFVFDDEGRRGMAVDSLVSGGCIVSGALVRRSVLFTGVHLHSYSSVEESVLLPEADVGRHCRLRKVVVDEGCRIPAGMTIGFDAEDDARRFHVSADGVVLVTVAMLEALRVSQA
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: MSD8_AMABI
Sequence: MSDINTARLPCIGFLGIPSVGDDIEMVLRHG
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:18025465).
What are the official names of this protein?
MSDIN-like toxin proprotein 8.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: Y1079_METJA
Sequence: MLNLLYLILGIICGTITGLFPGIHPNNIVALSFLILPYFGLDNYIPFLIGLVITHYFINFIPSAFLGVPDDETAVSALPMHKLTLNGNGYEAIVLAGFGSYLGVVFSILISLFLMSILHFDVRAFYCSIKIFIPFILIAFILYQIFTAKSVWEVLVIFLSGIFGIAVLYCSEAFNITLTAIFTGMFGIPLLINNLKTYKIKSQMMAFPDFELKFLKSSFFASVAGFFRIFLPGISGAQLNYILSKILNERDLKNFIVSQGSIILSNEVFSLLAVIFIGVGRSGVARAIQLLNANININTAIFSILISSTIAIIILLNLSKYILLFIRKVNFKFLSLFFIIFCSLVVIIGSYNTYLIYHIIVYLTAIYIGLLAVKSNTNLSNMMNVLIFPTILYFLRG
What are the official names of this protein?
Uncharacterized protein MJ1079.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1029_TREPA
Sequence: MSKISSKISSVDQEKFQAFLQQILRNVKTQEDPRVLDAYRRLFRKSVPFSMRSYVAAHLAHTHCRAGATAGSTRRTGAREGIRTGSAHAPSCASAPASAARARDFERKARDYPALCPGDTTSIFISIGKNRHIYPRDIIALLMQRADVAREHIGTIRILDHYSFIQVLSGEAEAVIARLNGLFYRGRTLTVSHSRRADEHPAPSTEPHAAAVAPEPDFMAEPIPALEE
What are the official names of this protein?
Uncharacterized protein TP_1029.
Protein: RRT5_ASHGO
Sequence: MSDQPAQSDLPDQGALPPQEAAQPQAVREDPQPQQCAQQVLFEQQGAQHRVYISNLSQDATEEALTEFLKDFHPVSVLIPSQSVRGFQKTSVRPLGIAYVEFKDADTAAKVILELNGVTFMDRELRLRYHIPFKSEKEKLARGPNKFRQIQRRLSELRRRNSDAGATVTTDNGPQVDAAAVPREMSKVTIYVGRLPGRTTDKDLRTYFHEYLPQEIIVFKHRQFRGWRIRRHVTAAVITFPDHERQESALESLSNLPFNGRTVRMAPAFEDKLAEIRAEVQRMAVEQQLPQPASNLGIYIGNNLIAMQPLQTRKADQQSLQSQHSPQNAAEDQTITAPPPSQQQLPQLQPIAPPLSLQPLNPVENTQPVQGLDLSIPREHEEVVRGQPLLRLQKLQMIQRLQRLHRQKQRQQIQQEPAAQPAAQPAAQPATEAAVAPQLVPEQEAHQAAAQAEPQQVLERPIAAGA
What is the function of this protein?
May be involved in the modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription protein 5.
What is the protein family that this protein belongs to?
Belongs to the RRT5 family.
Protein: ATPA_UREP2
Sequence: MTDNKNHSLISDIKSQIKKFSEKALTLEVGNVISLGDGIVLVDGLDNVMLNEIVRFENGVEGMALNLEEDAVGVVLLGDYSNIKEGDRVYRTKRIVEVPVGDVMLGRVVDALGKAVDNKGNIVANKFSVIEKIAPGVMDRKSVHQPLETGILSIDAMFPIGKGQRELIIGDRQTGKTTIAIDAIINQKGRNVNCVYVAIGQKNSTIANVVRELEAHGAMEYTTVVTANASELPALQYIAPFTGVTIAEEWMHQGKDVLIVYDDLSKHAIAYRTLSLLLRRPPGREAYPGDVFYLHSRLLERACKLKDELGAGSITALPIIETQAGDISAYIPTNVISITDGQIFMMTSLFNAGQRPAIDAGQSVSRVGSAAQIKSVKQTGASLKLELANYRELEAFSQFGSDLDDETKRILKLGKAVMAVIKQAPNKPYNQTDEAIILFTVKEKLIPQVPVERIQDFKEYLLNYFKGTKLRADLEDKKAFDKENTPAFRCAIQKAINSFLNNSQDFKPCEEAEQTAFDKFFNENESIVVDGENDFNFINEEVSLKPTTETSEAVQIEEKVQDFVEPQEILETNKMEENHIFEEVEPEKIICEHHEFEIAENQEKIEGQQVLEDTNHEYSIYETVEQSGEVDNDESKDDDLEVLVPVAEIEHDEAILDERENRNWVFSDSAVSEVEKQTIMISISSNEAEQLFDNAKSVVFFKVTPKYPVEKVLVYVTSPVQKVVGEFDLLKIDVNSVNTSWNKYRSSSVISSRKEYLEYFNSHKEAHALLASKVYKYRKPKDLASFNMNKGPSGFTYLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YOMP_BACSU
Sequence: MSNFWVIALNKNWATLDQVKEAYYYDDVTKEELKEGVDNNLITPEQYQEIVGEAYTSVTLSTE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomP.
Protein: METN1_STAEQ
Sequence: MIEFKNVNKVFRKKRETIQALKNVSFKIDQHDIFGVIGYSGAGKSTLVRLVNQLETVSDGQVIVDGHEIDTYKEKDLRDIKKDIGMIFQHFNLLNSKSVYKNVAMPLILSKTNKKEIKEKVDEMLEFVGLADKKDQFPDELSGGQKQRVAIARALVTHPKILLCDEATSALDPATTSSILNLLSNVNRTFGVTIMMITHEMSVIQKICHRVAVMENGEVIEMGTVKDVFSHPQTNTAKNFVSTVINTEPSKELRASFNSRKDSNFTDYKLFLDSEQIQLPILNELINEHHLNVNVLFSSMSEIQDETVCYLWLRFEHDESFNDFKLTDYLSKRHIRYEEVI
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TX35_ACAPA
Sequence: MNTIQVILFAVVLVLTVTVGQADEDSAETSLLRKLEEAEASMFGQYLEESKNSREKRCAVENVPCDKDRPGCCREYECLKPTGYGWWYGSYYCYKKKERLIST
What is the function of this protein?
Shows a weak inhibition on the voltage-gated calcium channel Cav2. 1/CACNA1A (28. 06% at 1 uM).
What are the official names of this protein?
Omega toxin Ap5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 08 (Ltx-4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHJ_TRIEI
Sequence: MAESEAPIIEAGKVSKWLTDNGFDHEFLAPDHQGIEIIKGNRDFLIPLATALYAYGFNYLQCQCAYDAGPGEDLVSMYHLVKVSDDVEQPEEIRLKVFVPRDDPRLPSVYWIWKSADFQERESYDMYGIIYEGHPNLKRILMPEDWVGWPLRKDYISPEFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RRP36_AJECG
Sequence: MPISSTLNQRVRARLENDGFEHFSDESVSNEALDEGESNEDTEQDNSDQRETDDDDTEDDGHTEISDINPSLNTISFGALAKAQAALGKRKRRTTSTTDITPKRTKVLSRQSPTPSTSSNKEHDQCQGLSEFQKHLASNAKKPPQKLTHRTSKHAPTIQSSRHAVSRKRTILEPLAVPKPRDPRFDSVVLSHSTNGDPSTAANADIHARNNYAFLNHYRTDEIAELRKQVSALQTKKKKTERDDHEIVRLKREITSMSDRQRAFERKEMEREVLVQHRRREKELIREGKKSQPYFLKKGEVKREVIAKRFTEMSGKEKQRALERRRKKVAGKERKEMPWGRRGVE
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: I3BB_CONCB
Sequence: MKLVLAIVVILMLLSLSTGAEMSDNHASMSANALRDRLLGPKALLCGGTHARCNRDNDCCGSLCCFGTCISAFVPC
What are the official names of this protein?
Conotoxin Ca11b, Ca-24, Ca11.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APT_STRP1
Sequence: MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYACDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIRNYDYKVLMQFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_ECOK1
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVIAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: DCDB_CLOBB
Sequence: MILSGKEILKHIGEDIVIEPFSEERINPNSYNLTLFNELLVYKNETLDMKIPNETEKLIIPEEGLLLEPGKLYLGRTNEFTQTNKYVPMLEGRSSTGRLGLFIHVTAGFGDIGFAGYWTLEIFCVQPIKIYPNTEICQIYYHNIDGEYDLYNSGKYQNNNGIQPSLMYKDFEK
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RL4_PHYMT
Sequence: MPKYNLINQKGDFLSQIDLDDEIFGISINKQVLYDVVNAQRASMRQGTHATKNRALVSGGGKKPWRQKGTGRARHGTIRSPLWRGGGVAFGPSPRDYSVKVNQKVRRLALKMALSWKINNKNLILIDNINLETHKTKEFQNILDQLNIQQKTLILTKDLNHNLCLSIRNLSKVLLETVSHVSVYQLLSYSTIILTKEAANYFEENLK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: IF3_PROMA
Sequence: MPPRPRFDRRAPVRELPNINERIKYPKLRVVDADGTQLGIISREEALDVAQDRELDLVLVSEKADPPVCRIMNYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDEHDYQVRIGQATRFLKAGDKVKCTVIFRGREIQHTNLAESLLARMAKDLEEPAEVQQAPKREGRNMIMFLTPRKTPLIKKEQELEEASKAKRTI
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA1_DEIGD
Sequence: MTIRRPGGACLFGLLLAVSPTPFPRRTTLTPIRTLLTPFGEFFKGQASSGLVLILAAVLAFAWANSPWRESYFTLRELPLTLSLGSWTLSHGLYWWVNDLLMALFFLLVGLEIKRELRVGELRHPRQASLALFAALGGMLLPAGLYTLVNAGGPGAAGWGVPMATDIAFALGVLALLGDRVSPGLKVLLAALAILDDLGAVLVIALFYTSGLNLLALGLMGAVWALGLGLNAAGVRHLGPYAVLGAALWLTTLASGLHPTVAGVLLALTIPLGRRAEQEDAEPSPLHRLEHGLHPWSAFLILPLFALFNAGVSVAGGSLDRVTLGVVLGLIIGKPLGVVAFAWLAVQLRAASLPEDVTWPGMLGLGLLAGIGFTMALFIGGLAFPEGALLNAAKLGILTASVLAALAAITVLTRAFPRQPR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3G_LODEL
Sequence: MSSAIESWADAGDEFSVPADIIQNPDGTKTVITFRTNQDGKKVKITQKIKEVIVREKVHPLIAQRKNWAKYGKEKHSSPGPDTSTTQLGEKVDLKLGLSWKQVEKKEEEDKAQERASRVVVQTIKCRVCGGDHYTAKCPFKDTLGASTLNGGTPEPGSEGAGDADAVTSTGRYIPRHLRPDANGNIPTREARDDSTTLKVSQLNTFVDEDMLRNELFARFGPLQRVTVVRDRETGESRGFAYVSFATEEIAQKALDLLNGKGYHSLILHLEWSKKKKPL
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOB1B_ARATH
Sequence: MSLFGLGRNQKTFRPKKSAPSGTKGAELRKHIDATLGSGNLREAVKLPPGEDLNEWLAVNTVDFFNQVNLLFGTLTEFCTPENCSTMTAGPKYEYRWADGVQIKKPIEVSAPKYVEYLMDWIETQLDDETIFPQKLGAAFPPNFKEVVKTIFKRLFRVYAHIYHSHFQKIVSLKEEAHLNTCFKHFILFTHEFVLIDKKELAPLQELIESIIAPY
What are the official names of this protein?
MOB kinase activator-like 1B, Mob1 homolog 1B, Mps one binder kinase activator-like 1B.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.