PharMolix/UniProtQA huggingface dataset:
Protein: ATG7_EMENI
Sequence: MQYTPFASDIELPFYIALASLKINHDKLDDSARKVLGLYELRPSDAPNASCRIQIHGNALTSDEVPSTYYRAEGMIKNVNTIEEYAKADKMGMLQQSGETIWNAINNGTIYSCPSLLSAFVILSYADLKKYKFHYWFAFPALHSDPSWTPLEEGCEGAQAHRLPSVESSALARSVQEWARVVDAPQRGFFLARRVRMRDDDTVSWKIASLSSYEDGFFKHAEFADCFTCFVDPSNYEEAPGWMLRNLLVLVKRRWGLTKVQILRYRDGPSPRDCGRSIVVTLRLKTSQLPDGGVKDDRMPKVTGWERNPSGKLTGRIVDLTEQLDPKRLADQSVDLNLKLMKWRISPNLDLEKIKGTKCLLLGAGTLGSYVARNLMAWGVRKITFVDNGSVSFSNPVRQPLFNFADCLDGGAKKAYRASQALSEIYPGVESVGHVLAVPMAGHPVLDAEKTKADFEVLKGLIDAHDVIILLMDTRESRWLPTVMGKAAGKIVMNAALGFDTFVVMRHGVTNNEHPEEELGCYFCNDVVAPMNSQKDQTLDQQCTVTRPGVAAIASALLVELLVSLLQHPLGAAAGAPQTPNNTQNDHPLGVIPHQIRGFLSTFENVSVVGRSYKCCSACSRPVIDEYKKNGWNFVQKALNEVGYVEELSGLKEVCHPPLSIA
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the atg8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme atg7, ATG12-activating enzyme E1 atg7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: ATPZ_RHOCA
Sequence: MSEEVGGEPDPERLAALEKRLSQLKKTEEAPKRAADGDLRMADMAWRMVIELVSGLGIGFGIGYGLDAVFGTQPFLMLIFVFLGLAAGVKVMLRSAADLTKAQARAAAAGKEGK
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: ZNUC_VIBVY
Sequence: MSALISLKALSVTFDDKKVLDSISLDLHKGKITTLIGPNGAGKSTLVKIIIGLLKPTSGQVQRQAKLTIGYVPQKLKLNDTLPLNVIRFLNLSGKYSQQETMEALRLVGAEHLYKSNMHKLSGGETQRVLLARALLQRPDLLVLDEPAQGVDIQGQIDLYDLIESIRHRFDCAVFMVSHDLHLVMAKTDEVICLQHHVCCSGAPEDITQHPSYIALFGSAARDSLAIYHHQHDHHHHDLAGQPVSGDATQCNHHHHGHHHD
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NLTP2_BRANA
Sequence: MAGLMKLACLVLACMIVAGPITSNAALSCGTVSGYVAPCIGYLTQNGPLPRGCCTGVTNLNNMARTTPDRQQACRCLVGAANSFPTLNAARAAGLPKACGVNIPYKISKSTNCNSVR
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 2, LTP 2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: LEUD_STAAW
Sequence: MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPFAFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIIIAGSFSDIFYMNCTKNAMLPIVLEKNAREHLAKYVEIEVDLPNQTVSSPDKRFHFEIDETWKNKLVNGLDDIAITLQYESLIEKYEKSL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: YC9G_SCHPO
Sequence: MASSSSSSGSSSPASKRSSRKRQTPPMPELPSFLLAFPHAPPLGFLRPKLNSLVVQVKRQGITAEPVFNLYSRFSVHTLSHNLVLDNVSSESNKTSAVFCKRHVGSSQVVIKIYSPHIKDYLPWTISCTKNEWVFDMLASFSIENSLRIKWVAPDKAKLNETWKCYLHIQDVKKSYFLASLTSRSLQFEGGSVGLSNRIITHRELEMVILSTSLCVQLSLLNLLPNYFPKP
What are the official names of this protein?
Uncharacterized protein C584.16c.
Protein: PYRG_PROMH
Sequence: MKTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTMMKLDPYINVDPGTMSPIQHGEVFVTDDGAETDLDLGHYERFIRTKMTRRNNFTTGRVYSEVLRKERRGDYLGATIQVIPHITNEIKERIIRGGEGHDVVLVEVGGTVGDIESLPFLEAIRQMAAEVGREHTFYLHLTLVPYLAASGEVKTKPTQHSVKELLSIGIQPDALICRSDRVIPANERAKIALFCNVPEKAVISLKDVDSIYKIPALLKSQGLDDYICKRFSLDCPVANLSEWEQVIYEEANPEGEVTIGMVGKYVELPDAYKSVIEALKHGGFKSRVAVNIKLIDSQDVETRGVEILKGLDAILVPGGFGERGVEGKIMAARYARENKIPYLGICLGMQVAMIEFARNVANMEDANSTEFAPDCKYPVIALITEWRDENGNLEVRTENSDLGGTMRLGAQPCHLSGDSLVRTLYGKNTITERHRHRYEVNNLLLKRIEDAGLRIAGRSVDNKLVEIIENPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAFDYQKGLLK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y9372_DICDI
Sequence: MDTPNNRGINIRFVTNKKVLWPEDVAAKLFSQYQTMLATKLYTKDMEIVEILSGTTPFKGVYTLEQIKSKIKNQKHSLSMKNLALQKTSQQIDSSPPQTPTTSNGSMMTRRQNANNAISSNNNTNTNVTNGSSSNTSLNGGDEEQEEEEEEENDEDSITNKEDSDSYDDFSIVEETTDIREVQDTRSFKKVKLNSLTSLNEGYIVPPTPQIEMVSPNRNNNNNNINKNNNNNINNNNNNNNNIFNFLQDQDQNQNKPNKPNNQSNFSNQSQQLQNLINATANENKKLKLSMEQLEFQLKMEKEQNLKLKNLVTKLNEEIQLEKEISKQINKSICSNLNIQNSRSISTNSVIFKKDSNDDSIVAIFPTFITTTNSNSSEITLTIDPNPPENYHKIIIKQQLHQHHQHQQQQQQQQPQIQTYLIKKLQDYYDPEPCLIGSTNSKGVYFKSKDKSLLKISIDNLRDFD
What are the official names of this protein?
Uncharacterized protein DDB_G0288739.
Protein: HIS5_SULDN
Sequence: MIAIVDYNMGNLASVQNAFAKIGTQTVIEGDPKKFKEYDKLILPGVGAFGDAMEHLRERGMIEAIKEFAASTKPILGICLGMQLLFESSEEFGEHEGLGLIKGKVVAFDTSKFEETLKVPHMGWNRMFTKEHPLFEGLDEEHYLYFVHSYHALCDDEKDSIGRTFYGYEFTSAVAHDNIMGIQPHPEKSHDNGLKILENFTKYRNLK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_OENEH
Sequence: MTRRYWNINLEEMMEAGVHFGHGIKKWNPRMAPYIYANRKGIHITNLTKTARFLAEACDLVFDAASRGGQFLIVGTKKQAAALVARAAIKARCHYVNKKWLGGMLTNWSTTETRLHQFRDLRTEQKTGRLNRLPKRDAAILKRQLSHLQTYLGGIKYMTGLPDILIILDQQEEYTALRECITLGIPTICLIDTDCDPDLADLPIPANDDAMASIRLILNKLVFAICEGRSSSIRNP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1949_CLOB1
Sequence: MSRLSKEEISERLLELIKDETKPAIGCTEPVAVAFTVATGKKYMAGEVLKIDLKVSKNILKNGKSVTIPNTEVCGLDIAGALGEICGDPEEGLFVFRNVNNEYLDKAKEMIKNKVVTLNPIENTDPVFVEATLKGEQDEVIAILKGGHTNIEKVIVNGKIAFEKDNKNKKDNKDCDFIKELSLKDIRQITEDISIEKLDFIMDGIEMNKEAAKEGLKRQKGLTLGSSLLKLQEEGKIGKDSATIARILTAAGSDLRMGGGMCPIMTSGGSGNQGLCVILPINVVAEDIKAPKERLQRAVFFGHAVNNFVKKYTGKLSAICGCAIAAGIGATAGIAWLLGGKDKEIEGAILNMLANLTGMVCDGAKGSCAIKLSTSASEAVISAYLALNDIIVPNNTGIIGNTVEDTINNLGMLCKDGFYKADDVMLSIACKEVI
What are the official names of this protein?
UPF0597 protein CLB_1949.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: Y2632_SYNC1
Sequence: MKIWVDADACPAVIKEILFKAARRTGVSMTLVANHLMRIPPSPHIHFMLVAAGLDAADNEIVKKLDAGDLVITADIPLAAQVIEKGGHALNPRGELYTVDNIRERLSMRDFMDSLRASGIDTGGPAALNQSDRQAFANRLDQFLTRHV
What are the official names of this protein?
UPF0178 protein Pcar_2632.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: GLYA_ROSS1
Sequence: MSTLQTLWRSDPAVARIIDGEMRRQRDGLELIASENYASRAVMEAQGSALTNKYAEGYPGARYYGGCEWVDQVEDLARERVKELFGAAYANVQPHSGSQANMAVYFTFLRPGDKVLGMNLAHGGHLTHGSPVNFSGQLYTFVAYGIDPKTERIDYEQVAEIAHRERPKMITVGASAYSRAIDYAVFRQIADDVGAFLFADIAHPAGLIAKGLLPSPIKYAHVVTSTTHKTLRGPRGGIILMGEDFENPFGLKAAKSGRTLMMSELLDKMVIPGVQGGPLMHVIAAKAVGFGENLQPEFETYARQVIRNAQTLANALIARGYHVLSGGTDNHLMLIDLRNKAVSGKAAQEALDRAAITTNKNAVPNDDKSPLITSGIRLGTPALTTRGMKEPEMEQIAALIDDVITHINDDHVINRVREEVMALCARFPVPGLEPST
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_LACP7
Sequence: MLKMNLQFFAHKKGVGSTKNGRDSESKRLGAKRADGQFVLAGNILYRQRGTKIHPGVNVGRGGDDTLFALVDGVLKFERKGRDKKQASVYPVEAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL18_THEON
Sequence: MAHGPRYRVPFRRRREGKTNYHKRLALLKSGKPRLVVRKSLNHHIAQIVVYDPKGDKTIVSAHTRELMRDFGWKGHGGNTPSAYLLGLLIGYKAKKAGIDEAILDIGLHPPTRGSSVFAVLKGAVDAGLNVPHSEEIYPEDYRITGEHIANYAKALKEEDEGKYRKQFSSYLVKGLEPEKLPEHFEEVKARIIEKFEEARE
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MSRQ_ECOL6
Sequence: MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_LEGPL
Sequence: MAHKKAGGSTRNGRDSNPKYLGVKRFGGQFVNAGEIIVRQRGTRFHPGPGVGCGRDHTLYALVEGLVQFTTKGEKNRKYVTILPEQREEAAS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PPE12_MYCTU
Sequence: MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAAGAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASSAAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNGNVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGNANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNSGVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNGGDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISGFANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVSGFFHR
What are the official names of this protein?
Uncharacterized PPE family protein PPE12.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: PYRF_STRTD
Sequence: MRENRPVIALDFPTLEDVKAFLAKFPADEKLYVKIGMELYYAAGPEIIRYVKELGHSIFLDLKLHDIPNTVKSAMRVLSNLGVDMTNVHAAGGVEMMKAAREGLGDGPILIAVTQLTSTSEEQMRDFQNIQTTLQESVVHYAQKTAEAGLDGVVCSAHEVPKIKEATNQDFICLTPGIRPAGAAVGDQKRVMTPADAHQIGSDYIVVGRPITQAEDPVAAYHDIKAQWNDQ
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: LCAT_HUMAN
Sequence: MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs) (PubMed:10329423, PubMed:19065001, PubMed:26195816).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines (PubMed:8820107).  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (PubMed:10722751).  Catalyzes the hydrolysis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor or PAF) to 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) (PubMed:8016111).  Also catalyzes the transfer of the acetate group from PAF to 1-hexadecanoyl-sn-glycero-3-phosphocholine forming lyso-PAF (PubMed:8016111).  Catalyzes the esterification of (24S)-hydroxycholesterol (24(S)OH-C), also known as cerebrosterol to produce 24(S)OH-C monoesters (PubMed:24620755).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, 1-alkyl-2-acetylglycerophosphocholine esterase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, Platelet-activating factor acetylhydrolase, PAF acetylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (PubMed:10222237).
Protein: RRP3_YARLI
Sequence: MAKATEKRVKRAKKEESGSESEDNDAIAQEILDTTKSDNEEEEPKKSSKNYTSVEVDESEEQTKTFKDLGVIDSICETCEELKFTKPTPIQAQSIPYALEGRDIIGLAQTGSGKTAAFAIPVLQSLYENPQPLYCVVLAPTRELAYQISETFEALGSAMGLRTAVVVGGMNMMTQAVALSKKPHVIVATPGRLVDHLENTKGFSLRTLKFLVMDEADRLLDMEFGPSLDKILKVIPRQRNTYLFSATMTSKVEKLQRASLVDPVRVAVSTKYQTADNLLQYMVFCPFKHKDTHLVYLVSENAGNSMIIFARTKSDTQRISLLLRNLGYGAIPLHGDLSQTARLGALNKFKSGSRNILIATDVASRGLDIPAVDLVINYDIPSDSKSYIHRVGRTARAGRAGKSVALVSQYDLELYLRIEGALGKKLDSYPLESEAVMLFSERVAEASRAAIQEMKGEDGTKKRSKFDKKRRRDEMDIGEQ
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_METNO
Sequence: MRIILLGPPGAGKGTQSARIVEQFGIPQLSTGDMLRAAVAARTPVGLQAKSIMESGGLVPDEVVVGIVADRIDEADARKGFILDGFPRTVAQAKALDAMLAAKGLSLDAVIEFRVDEEALLGRIAKRAAETLARGEAVRKDDTPEVFKTRLDAYRSQTAPVSDYYAQTGLLRPIDGMAPIDDVSRAVEVLLRGLQPVSA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SYNY3
Sequence: MAITPTQLLDWKRQQRPIVALTAWDTAIASVLDAAGVEIILVGDSLGMVALGYETTLPVSLDTMIHHTAAVKRGVQRALVVCDLPFLTYQESPAQAMGSAGRVLQETGAQAVKLEGGHPRMVETVARLTEVGIPVMGHVGLTPQSVHQLGYRQQGQDPATAEKILHQAIALAEAGVFAIVLEHIPSELAASITEQLPIPTIGIGAGPQCDGQVLVTADLLGLTVKQPPFAPAYLNLRHTITETVHKFSGEVRQRQFPRRG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_MEGNO
Sequence: MVLSDAEWQLVLNIWAKVEADVAGHGQDILIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSRHPADFGADAQAAMNKALELFRKDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL32_SHIFL
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TBG2_DROME
Sequence: MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQGEKVQEEVFDILDREADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGLMMANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYEAATQIDYPQWSPAVEASKAG
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.  Required for oocyte activation and consequently for organization of the female meiotic spindle (PubMed:9155007, PubMed:9698447).  Essential for centrosome organization and assembly of biastral mitotic spindles in embryos.  Plays a role in stabilizing the augmin complex on the meiotic spindle (PubMed:23785300).
What are the official names of this protein?
Tubulin gamma-2 chain, Gamma-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Embryonic mitotic spindle, female meiotic spindle.
Protein: MURQ1_ENTFA
Sequence: MCKQMNLEGLTTEARNEATKKIDQVSTLEMVTLINQEDQKVAQAIEKVLPQIAAAIDAAAERFKKGGRLIYCGAGTSGRLGALDAIELTPTYSVSPERAFGILAGGEKAMYQAIEGAEDSKELAIEDLTQHQLTARDVVIAIAASGRTPYAVSAIEYGKKVGALTISVTCNNQSPMNQLAEIGIAPIVGPEVITGSTRMKAGSAQKMVLNMFSTGIMVKVGNIYQNLMVNVQPTNEKLIQRATNIIKEAAEIEESQAKEYLEAAQLEVAPAIVMAKAHVDFQKAKQLLAEHDGRISEVLA
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase 1, MurNAc-6-P etherase 1, N-acetylmuramic acid 6-phosphate hydrolase 1, N-acetylmuramic acid 6-phosphate lyase 1.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MRAZ_ROSS1
Sequence: MFLGEYEHTIDDKGRLAIPARFRDALNEGVVITRGFDKCLMGFPRSVWEELARQVSSLPIGSEETRQLQRMLFSGAADMTLDRQGRILIPQNLREFAELGDQAIIAGLNRHFEIWAPRRWQNVLSAMDANASLFAQKLAELRF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS12_SHIB3
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.