PharMolix/UniProtQA huggingface dataset:
Protein: RS4_SHEB2
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKPRLSEYGTQLREKQKVRRIYGVLEKQFRNYYKDAARTKGNTGENLLQLLETRLDNVVYRMGFGATRAESRQLVSHKSIMVNGRVVNIPSFKVSANDVVSIREKSRTQARIKAALEVAAQREKPTWVEVDNAKMEGAFKRVPERSDLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: FTHS_NATTJ
Sequence: MKSDIEIARGAPMRPIKDIASEVGIKDEELELYGDYKAKITFDAWKRLKDKPDGNLILVTAITPTPAGEGKSTTTVGLGQALKRLGKNTMVALREPSLGPSFGVKGGAAGGGYSQVVPMEDINLHFTGDIHAITTAHNLLSAAIDNHIHQGNNLDIDARRINWRRVVDLNDRALRNTVVALGGRGNGFPREDGFDITVASEIMAILCLATDIKDLKERLSKIIIGYTRDRQPVTVADLKMQGSMAVLLKDAIKPNLVQTYENVPAFVHGGPFANIAHGCNSAMATQMGVKMSDYLVTEAGFGADLGAEKFFNIKCRFAGLNPDAAVVVATARALKMHGGVEKDNLKEENLEALEKGFENLEKHMENINKFGVPAVVAVNRFPTDTEKELELLINKCQEKGYRVALSEVFAKGGEGGEEVAKEVLDIIDSKESNFKYLYDVDKSMEEKIETIAKEIYGASDVEFTPTARRNIKQLAQKGLDQVPVCMAKTQFSFSDDPKLLGRPKDFSITVKRVRISAGAGFAVAMTGDIMTMPGLPKQPAAEEIDIDDDGQITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: FKS4_SCHPO
Sequence: MSGNNENVSGITGHDAVSDDQYAYDSEVYDDQNAYQRQPADAYSNEEFLDQADYDSMYGEGYNGYDYPTGVTESYGDEYTPVDTASSGINQYSTEKGKFTRPSDEYESEYSDYNAQPSDANNFYNLRGDGRYNAYDPSSDSLANVYNSVPYGSSPYDFSNSSFVGNSGSGTPLDGDSGSFYADSANLTNREPYPAWTPENELPLTKEEIEDIFIDLTNKLGFQRDSMRNMYDFFMCLLDSRASRMTPDQALLTLHADYIGSDIANYKKWYFASQMDREDAVGLANVGIYGGKVTSIKEKGKFFSRNKKAPKVVKPPRKSRFKRKKKKEQPEEAEDEYIDVNTDDSLESAEYRWRSHMRSMTQFERAQQIALWLLLWGEANNVRFMPEVIAFLFKCAYDYIISPEAQNVTEPVPEGYYLDNIVSPLYQYMHDQQFEIINGKYVRRERPHDQLIGYDDINQLFWHAEGIARLIFEDGTRLIDIPASERFHRLPEVQWNRAFYKTYYESRSWFHLITNFNRIWVIHFGMFWYFTAFNSPTLYTKPFHQRDGPKPTGASQWAAVACTSVVSCIIMAAASLCEYLFVPRRFPGSKPIWKRLCIIVLIAIINLIPIVYIFGFSSKHQQRSGRRIAVGVVAFLMSIATYVYFSLVPLQSTFGKLSVKDSRKYLANKYFTSNFAPLKFDNQALSVIIWVCVFTCKFAESYFFLTLSIRDPIIVLSTMRPYLCSIYWAGSRLCFVQPRIILGIMYFTDLILFFLDTYLWYIIFNTIFSVLRSFVLGISILTPWRNIFSRMPQRIYGKILATNDMEIKYKPKILISQIWNAIVISMYREHLLSIDHVQRLLYHQVPAEEGRRTLRTPTFFVSQDDNIVHTTFFPANSEAERRLSFFAQSLATPIPEPVPVDNMPTFTVLIPHYAEKILLSLREIIREEDQLSRVTLLEYLKQLHPVEWDCFVKDTKILVEENAPYENDSVSEKEGTYKSKVDDLPFYCIGFKSAMPEYTLRTRIWASLRSQTLYRTISGFMNYSRAIKLLYRVENPEIVQMFGGNTDRLERELDRMARRKFKLVVSMQRYAKFTKEEYENAEFLLRAYPDLQIAYLDEDPPEEEGAEPQLFAALIDGHSEIMENERRRPKYRIRLSGNPILGDGKSDNQNMSLPFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEEMETDNVNPYSESARERNKHPVAILGAREYIFSENIGILGDVAAGKEQTFGTLFSRTLAQIGGKLHYGHPDFLNGIFMTTRGGVSKAQKGLHVNEDIYAGMNAMLRGGRIKHCEYFQCGKGRDLGFGSILNFNTKVGTGMGEQMLSREYYYLGTQLQLDRFLSFYFAHPGFHLNNMFIMLSVQLFMVVLINLGAIYHVVTVCYYNGNQKLSYDTSIVPRGCYQLGPVLSWLKRCVISIFIVFWISFIPLTVHELIERGVWRATKRFFKQIGSFSPLFEVFTCQVYSQAITSDLAYGGARYIGTGRGFATARLPFSILYSRFAVPSIYIGARFLMMLLFGTMTVWVAHLIYWWVSIMALCVAPFLFNPHQFDWNDFFVDYREFIRWLSRGNSRSHANSWIGYCRLTRTRITGYKRRVLGQPSDKISMDTPRAKFTNVFFSDVLIPALLAAGAIIPYFFINSQPGNPMFITDPNNPSPYVHDTKTGTNPILRLVIISLIPIAAGFGMSGFFGGMACCLGPAFGLCCKKFPSIFAAIAHTIQIFIFIAIFEVCWFLDGWSLPKTVLAFCAVTAIHRFIFKILTLLCLSREVKQDSANISWWSGKWYGKGYGYHAFTLPAREFVCKAIELNLFATDFFLGHLLLFFMLPVICIPYIDRWHSVLLFWLRPSRQIRPPIFSTKQNRLRKRIVRRYSALYFSILVIFLILIIVPLAAGAEIRQGLTASEAVAKGAVGWNQTNSSIGSGIIQPRDTNYTANYSFWYDRYHFEFNTTY
What is the function of this protein?
Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS) complex.  Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall (By similarity).  Required for maintaining cell integrity during cytokinesis and polarized growth (PubMed:15615781).
What are the official names of this protein?
1,3-beta-glucan synthase component bgs4, 1,3-beta-D-glucan-UDP glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 48 family.
Protein: TSC3_YEAST
Sequence: MTQHKSSMVYIPTTKEAKRRNGKSEGILNTIEEVVEKLYWTYYIHLPFYLMASFDSFFLHVFFLTIFSLSFFGILKYCFL
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).
What are the official names of this protein?
Serine palmitoyltransferase-regulating protein TSC3, Temperature-sensitive CSG2-mutant suppressor protein 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: YTR2_SPIAU
Sequence: MKASSHSTPVTVLTGFLGSGKTTLVNRLLKERPGTRFGLVVNEFGEAALESQLVESRRAP
What are the official names of this protein?
Uncharacterized protein in trpE 3'region, ORF 2.
Protein: KDSA_BURM7
Sequence: MNLAGFEVGLDKPFFLIAGTCVVESEQMTIDTAGRLKEICATLGVPFIYKSSYDKANRSSGKSFRGLGMDEGLRILAEVKRQLNVPVLTDVHEIDEIAPVAAVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLSEDRFMACERGVSFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLARAALATGVAGLFMETHPNPAEAKSDGPNAVPLGRMAALLETLVTLDRAVKRVPFLENDFN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_CLOP1
Sequence: MSDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSDKEVVTLQINGGGMAKGVTVTAYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLTVIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAVALGVLVDRDHSIKKAGGFIIQLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCDCSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADEVSEEMKKAEEKEKEEKNKK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_MYCSK
Sequence: MAIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGKGGRNAHGRITTRHKGGGHKRAYRVIDFRRHDKDGVDAKVAHIEYDPNRTANIALLHYLDGEKRYIIAPYGLKQGAIVESGANADIKPGNNLPLRNIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGKEGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRMRWKGKRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRKPNKPSDKLIVRRRRTGKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CATA_CALJA
Sequence: MADSRDPASDQMKHWKEQRAAQKADVLTTGAGNPVGDKLNVITAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPLLFPSFIHSQKRNPQTHLKHPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGLRDLFNAIATGNYPSWTFYIQVMTFSQAETFPFNPFDVTKIWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFSYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEHQPSALEHSTRCSAEVQRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFREVHNDYGTRIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
What is the function of this protein?
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.  Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: T2R46_MACMU
Sequence: MITFLSITFSILVGVIFVIGNFANGFIALVNSIEWVKRQKISFADQILTGLAVSRVGLLWVLLLHLYATEFNLAFYSVEVRITAYNVWIVTNHFSNWLSTSLSMFYLLKIATFSNLIFLHLKRKVKSVILVTLLGPLLFLVCHLFVMNMNHIVWRKEYEGNITWRIKLRSAMYLSNVTVTMLANLIPLTLTLMSFLLLICSLCKHLKKMQVHGKGSQDPSTKVHIKALQTVTSFLLLCAIYFLSMILSVWNFELEKKPVFMFCQAVIFSYPSTHPLILIWGNKKLKQIFLSVLWNVRYWVKGQKPSSP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 46, T2R46.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: BIOD_CORDI
Sequence: MAIVVVTGTNTDVGKTIASAAVCQHYSRQGFRVVPVKPVQTGEPKGSGDAQTIEKLTGIVGKCFARFPEPLAPNLSAQRAGMQQLNLEEIVNKIRELDGPQTVVVVEGAGGLLVRLADSFTIADVAAQLDAPLIVVTNMALGSLNAAELTVEAAQRRGLKVLGLIGGSMPKNPDLATSLNVAEMEKVTGIPLWGSIAEGAGQLSKEAFCQLVEDLHLPTMWP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APE2_SACS2
Sequence: MIKVNRYEIFLDFSFQTGDYKGYEKIEMESDEETVVLDAVGLKIVKAKVNGKEIEFSQDESRVNVKSGSFSGILEVEFEGKVTERKLVGIYKASYKDGYVISTQFEATHARDFIPCFDHPAMKARFKLTVRVDKGLKVISNMPVVREKEENGKVVYEFDETPKMSTYLLYLGIGNFEEIRDEGKIPTIIVATIPGKVQKGRFSMQISRNSIEFYEKYFEIPYQLPKVHLIAIPEFAYGAMENWGAITFRETALLADDSSSVYQKFRVAEVVAHELAHQWFGNLVTLKWWDDLWLNESFATFMSHKAISQLFPSWNFWDYFVLNQTSRALEKDSVSTTHPIEAHVRDPNEVEQMFDDISYGKGASILRMIEAYVGEENFRRGVVNYLKKFSYSNAQGSDLWNSISEVYGSDISPIMADWITKPGYPMVRVSVSGKRVSLEQERFSLIGNVENLLYKIPLTMEVNGKVVTHLLDKERDTMVFEEDVKSLKVNVNRTGFYRVFYYNNSDLVFNSNLSELDKWGIINDYWAFLLAGKIGFKEYERVISKFFNDKDFLPVNELSNELFTLHAINPDKYQGIAKEFHRIQLKNWRNSKDELGRLTYSNILYRLAAIDDEFSLGLSELFRFYGSLDSDTRQGVAVAYAITYEDNSVDELLERFRKETFDEEKLRYLTAMLFFRKPYLVGNTLSLILSGEIKKQDIPLTLSTAAYNPYAKSAVLNWIKMHINFMREAYKGTGILGRRLAEVIPLIGIGAERETEQFFSNLNMPEAERGIGTGLELLKAYSRLK
What is the function of this protein?
Preferentially acts as a leucyl-aminopeptidase, although it also has activity against other substrates.
What are the official names of this protein?
Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_SPHAL
Sequence: MPKRILTGTVVSDKGDKTVVVKVERKVKHPLYGKIIRRSKKYHAHDEDNAIKAGETVRIEETKPISKLKTWKVLDKVETSTKAKAAEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LPG1_LEIDO
Sequence: MAPPRWHHDRRRMAIFVRVGLYTLLFLMGYVVPLIIFYNRSRADTFEDTPRSGEAFISDENFFHCIAERLSYKEQHPARIPYVLIPVTMDYQDIKQLFCNITVPMTYIMFINNGMFRPLRSLLDRLAVDLRDYVDQNLFIIHHPENIAYASAVNEGLRHALNFSVAKVPWVFITNADVRFAPGLIDEFVSQANEKTQGQLERIRRLDQEIIAEARTLRNVPNRRFAFRSSQHPIITASSLPYRIRTMPPEEMKKQFADTYGIFYTDHKDFMATFALSRLAIATVGFFDENYYPAYGEDHDYVWRMAALGYQKYFSEPGKFVHFENANLNVGGSARNRGIFKNTAYFLQSVKFGRMNYQPFRLQYRRAKWFPDGVTIYQDTGRNPLPFNGTIPLDMWVLDTDRRRSIWEIGENIRCHRDYKPYSMKLLDFPVDPS
What is the function of this protein?
Glycosyltransferase that may be responsible for the addition of galactofuranosyl residues to the nascent lipophosphoglycan (LPG) chain.  It could alternatively be involved in the synthesis of the galactofuranosyl donor.
What are the official names of this protein?
Galactofuranosyl glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ESXK_MYCBO
Sequence: MASRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMTQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxK.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: MTNN_YERPS
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLASSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIEAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RL21_FLAJ1
Sequence: MYAIVEIAGQQFKVSKDLKVYVHRLANEEGSKVSFDKVLLLDDNGNVTLGAPAIEGASVEAKVLQHLKGDKVIVFKKKRRKGYKKRNGHRQYLTQIVIEGITAAGGTKKAAAKKAVVAEEAAATEEVEAAPKAKKAAPKAKKEATKE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SECA_BACP2
Sequence: MLGILNKVFDPTKRTISKYEKKANEIEALAQDFEKLSDEALRNKTIEFKEKLEKGQSVDDLLVEAFATVREASRRVTGMFPFKVQLMGGIALHEGNISEMKTGEGKTLTSTMPVYLNALSGKGVHIVTVNEYLASRDAEEMGKIFEFLGLTVGLNLNSLDKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHYAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKIEDDFTYDIKTKSVQLTESGMTKAEKAFGIENLFDVKHVALNHHIAQALKAHVAMQKDVDYVVEEGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEVQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMQVVTIPTNQPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDTTPIQSKMVSKAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDSDNLKSIVINMIQSSIERAVGSYTPKEELPEEWKLDGLVELINTNYLDEGAISVKDIYGKEADEITSFIMDRIKEKYDAKEETYGDEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRAYAQTNPLREYQMEGFAMFEHMVASIEDDVAKYVLKSEIQNNLEREEVVQGQTTAHQPQEGDEEKTVKKKPVRKVVDIGRNSPCHCGSGKKYKNCHGKTE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RBCR_NOSS1
Sequence: MSDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLSYGEKILSLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELTESLEIIPYAEDELALILPVFHPFTKLDTIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKNAVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEILPQFATPDWNQDVLKLAQKKLVVNVLDAAIPNTSDDG
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SLU7_XENLA
Sequence: MLGGTDIMATPQGGEPGGLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYVDPSKRPTLKHQRPQDEKQKYFSQMDEWYKKGVKEGSITTKYRQGACENCGSLTHKKKDCFERPRRVGARFTGVSIAPDEYEQPQLMLDYDGKRDRWNGYNPEEHTRIVEEHSKVDLAKRTLKAQKLQEELASGKLSEQVSSPRHQWGEDEQNSQTEKDRNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDTAKYLRNLNLNSAYYDPKTRAMRGNPYADAGKTPEEVSYAGDNFVRYTGDTISMAQTQLFAWEAYEKGSDVHLQADPTKLEVLAQSFKVKKEDFEHEQKKSILEKYGGQEHLNIPPVELLLAQTEDYVEYSRHGTVIKGQEKAVAKSKYEEDILINNHTCIWGSYWKDGRWGYKCCHSFVKMSYCTGEAGKDINNTDICEEDLMPTEEEMTKPKTLVEIHQEKLKDKKKKKKHRKSGDSDSDNDEKKKKDKLKKALNAEEARLKQVEEMMQLDERKRGYNSVYESREPTEEEMEAYRMKRLRPDDPMASFLGK
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.  Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region.  May be involved in the activation of proximal AG.  Probably also involved in alternative splicing regulation.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Predominantly nuclear.
Protein: YHAM_ECOLU
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: CBR1B_XENLA
Sequence: MSQTPEARTRDNQTRQIQESVNNVEKHFGELCQIFAGYVRKTARLRDKADLLVREVNTYADTETPTLKHGLKNFADEFAKLQDYRQAEVERLESRVVEPLKSYGGIIKLKREDLKVTLSARNREAKQMAQLEKTRQRNPSDRQIISQAETELQRATMDAARISQQLEETIDNFEKQKIKDIKKLFAEFVTIEMVFHGKALEVLTAAYQHIQDIDEEEDLEVFRNSLHPPDFQSRLDIVRANSRSGSTSRAPSVISQPPGNRQKNRMEDDEDGEDDNDENSTEDEN
What is the function of this protein?
Acts as a positive regulator of ciliary hedgehog signaling (By similarity).  Plays a role in ciliogenesis (By similarity).  Plays an important role in the mitochondrial function and is essential for maintaining mitochondrial morphology and inner membrane ultrastructure (By similarity).
What are the official names of this protein?
CBY1-interacting BAR domain-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the CIBAR family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: T2DP4_PIRLC
Sequence: ACATKNQRCASWAGPYCCDGFYCSCRSYPGCMCRPNS
What is the function of this protein?
Binds at site 4 of sodium channels (Nav) and inhibits the fast inactivation of cockroach channels.  This toxin is active only on insects (By similarity) Has a potent activity against S. litura larvae.
What are the official names of this protein?
Delta-amaurobitoxin-Pl1d, Delta-AMATX-Pl1d, Delta-palutoxin IT4, Delta-paluIT4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 01 (aga-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASR_ECO45
Sequence: MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PDXH_JANSC
Sequence: MSERSGIFAGDDPFVLARAWLAEAEASEPNDPNAIALSTVDADGLPNARMVLLKEIESHGAGQGGFVFYTNYGSAKGQEIAQAGKAAFVCHWKSLHRQIRVRGLTETEDGPQADAYYASRSLKSRLGAWASDQSKPLSSRGALMADVARVTAEQGTNPKRPPFWGGVRITPLEIEFWADGAFRLHDRFQWRRGSVDDPWEVQRLNP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YVZC_BACSU
Sequence: MPVEKIQIRRDYVLQYMVNNDYSLNQLALEIGVSPATLSRVLNGERRPGQLVIGKMLHYFNLKFEDLFYYDFVDKSQ
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YvzC.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM32_YEAS2
Sequence: MLRITVKTLQQRASFHHSFKHISVPDLHTRAQNDQTNCYCQEINARLPSKTDPLDPHIKLPHRTPNYNKHVLLLSPGDRFAQPWKVAWNHNLDTNTNRPYNAISKLRSHLGGSPGILINAVHLQNEFIPRPKQHDEWLYFFVIPDMKLYVIKETDIEEFASFLDEGAIQAPKLSFQDYLSGKAKASQQVHEVHHRKLTRFQGETFLRDWNLVCGHYKRDAKCGEMGPDIIAAFQDEKLFPENNLALISHIGGHIFAGNVIFYKLFGREKMQNKLDSLWFGKVYPHNLKLLCENLENGKIIDEMYRGGISMN
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: NEL1_YEAST
Sequence: MCSPTNFLYEPFSSDAVTQNYDQNLKCTKCGAYYSMACSLREQNVWTCLFCNQSNSNAELPLVPSNTYTLTSAKKEILSRRTIMIIDAICDPHELNYLVSILCNNYITRQQEPLSIITIQQSGHVILHNAVNHRRDAVFSINEFMTKYNLDKLNASYFEKKISEINQESYWFDKSTQGSLRKLLREICKIANKVNISSKRDKRCTGLALFVSSVLASQCSLSAYCHIVSFLNGPCTKGGGKVMSRERGESMRQNHHFESKSSQLQLSKSPTKFYKKMLEKFANQSLIYEFFIASLDQIGILEMSPLITSSMAVSQFDSFNDERFAMSFQKYLNLRDHNAIYNCHSKIMTAKNAIVVKDFPKYSLNPKNLSLPLEISLGHNSAEAPIQFQTTFENQTEKYIRIETLLLPKANRSFGAQNEIVFSMKKIASRIIDSFAYSSKHTKELMKQLFLLPNQIRGKDVDMVNLIQWCYHIYRSPILSVRNTSPDERYLFLHRIINASKDTCLSLCKPFIWSYSDLKHDWIVLDVPLTRAQILQDDKTTICVDGGSYLVLRRGKLLEKEGRELCCKLLNDLQRFPQPLYVETKTGGSQDRFLKSKIIPLDITDKETLGTEDMTFNEYFNLFTDLSGSK
What is the function of this protein?
Acts as a GTPase-activating protein (GAP) for SAR1 (PubMed:24947508).  Contrary to its SEC23 homolog, NEL1 does not associate with SEC24 and its homologs, nor does it associate with the COPII components, suggesting that it is unlikely that NEL1 functions as a structural component of the vesicle coat machinery (PubMed:24947508).  May function as a signaling molecule (PubMed:24947508).
What are the official names of this protein?
GTPase-activating protein NEL1, Non-ERES-localized SEC23 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Is diffusely localized throughout the cytosol, and does not accumulate at ER exit sites (ERES).