PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_RUMCH
Sequence: MVKEAVKIVAQNKKARHDYFIEETIEAGIVLSGTEVKSVRQGKLNLKESYASIVEGEVIVSGMHISPYEQGNIFNKDPLRDRKLLLHKSEINRLIGLTQQKGYTLVPVQAYLKRGMVKIELGVARGKKLYDKRDDIAARDAKREIDRKMKEQLR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y2394_CLOBM
Sequence: MPNKFLIIDNSILPDIFEKVVKVKELLANGKVKDITEGVKTVGISRSTYYKYKDFVFSVSEGVKSQKATIGLLLGHERGTLSKILDRIAEYQGNILTINQDIPINNTANVSITFDISQMSIGLKELVEEIKNTKNVIKVDLIAME
What are the official names of this protein?
UPF0735 ACT domain-containing protein CLK_2394.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: AAKB1_PIG
Sequence: ILMDSPEDADLYHSEEIKAPEKEEFLAWQHDLEVNDKASAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPEGEHQYKFLVDGQWTHDPSEPVVTSQLGTVNNIIQVKK
What is the function of this protein?
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) (By similarity).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb, 5'-AMP-activated protein kinase 40 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Protein: KCY_STAAM
Sequence: MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BACC2
Sequence: MDKRISIAIDGPAAAGKSTVAKVVAKELSYVYIDTGAMYRTLTYAALEQKVDIENEEQLMEVVRNVNIEFQQGENTQLVFLNGQDVSEVIRTPDVTNRVSIVAKHRLVREEMVRRQQDLAKKGGVVMDGRDIGTHVLPDAEVKIFMLASVEERAERRHLENLNKGFDSNLEQLKEEIAQRDKLDSEREVSPLKKADDALELDTTSLSIEEVVQKIMSIVSGVFAK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_PERMH
Sequence: MYTKERERELIQRTKELLKIKKEHIKTKEDAEAIIEDLRDVIRYHDWRYYVLANPVISDYEYDQLFHLLKDIESRFPELITPDSPTQRVPSELTKEFPQVKHLAPMLSLDNSYNEEDLREFDRRVREAVGIDIIEYAVEPKFDGAGISLVYEKDMFVRGATRGDGVVGEDITPNIRVIKTVPLSAEFSVYGIDRIEIRGEVLINKEKFKEINHQRLEEGLPPLANPRNAAAGSLRLQDPKEVAKRGLEAFVYQITYAVDKDGNNLLGNKLRYHYDSIKILYELGFKSPYKEIKVCRGIDEVIDYCREWERKRDDYPYEIDGMVIKVNDISLYDRLGVTSHHPRWAIAFKFRARQATTKIIKVVFQVGRTGAVTPVAKLEPVEIGGVTVSSVSLINEDFIKEKDIRVGDLVLIERAGDVIPYVVKVVTEARTGKEKPIQFPKECPSCGSPLVKPAGEAVWRCININCPAQVVERIIYFASKDAMDIRGLGEANIRKFYQLGFLRSIPDIYRLPYDKIIQLEGFGQKSVENLKKAIEESKNRPINRLITGLGIRFVGKVTARTLAENINCVEDLKDWSVEDLERLPDVGYVVAHSIYDFFHNPDNIKMIQELKRLGVQTCKEKEEVVENIFEGKTFVFTGTLSCCSREIAQEIVERLGGHASSSVSRKTSYVVVGENPGSKYRKALSLGVQILDEKQFIEMIKDHIPDDLKDKVHL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ADRO_SCHPO
Sequence: MLSRFIKRTYSTQTSSPVVGIIGSGPAAFYTAHRLLRNDPNVKIDMFESRPVPFGLVRYGVAPDHPEVKHVEHKFSEIAESTQFRFLGNVNVGTDVSLRDLTKNYDCLVLAYGAAGDKRLGIPGEDLSGVYSAREVVGWYNSDPRNQNLELDLSQVEDAVVIGHGNVSLDVARILLSNPAQLSPTDINPLFLKSLERSNLKRLHIVGRRNIFSVSFTIKELRELFALSSAVFFAPSFNYSTKWMNETDASGLDRPRKRLLKLLVSEIQKAVSEKRVAPYSKDKKCWNLEFGLTPVEILGHKGNVENVRFQITDSIRTDAESKFTTIPAQLFIRSIGYKSMPLPGMKDVGVPFDDAKGIVKNVNGFVRPGIYTSGWVKHGPIGVIATTMMDAFATADTITKDWKSKKEFLKNSKLGWDGLKKNIKTPVIHWKDWKVIRNAEIERGLRHESLSEKFRSNEDMIKLIYPGKK
What is the function of this protein?
Acts as an electron transfer protein.  Essential for viability.
What are the official names of this protein?
Probable NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: RNPA_BRUSU
Sequence: MKSKKQILRLRKRAEFLTVRNGEKRRGPLFLMEVRERTEEESNAAKTGDNPRVGFTVTKKNGNAVIRNRIRRRLKEAIRCHAGRDMAPSTDYVIVAREQALNAPFSQLTEELSRRITAKGERRSGRKRRTERPEPGPVNGK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PTH1R_PONAB
Sequence: MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCGKRLKEVLQRPADIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTDSRYRGRPCLPEWDHILCWPLGAPQGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVQFLTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLHFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPATAAPKDDGFLNGSCSGLDEEASGPEQPPALLQEEWETVM
What is the function of this protein?
Receptor for parathyroid hormone and for parathyroid hormone-related peptide.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXB_AZOVD
Sequence: MRILADENIPLVHAFFSAFGEIRQLPGRAIVSGSLGDADVLLVRSVTRVDAALLEGSRVRFVGTCTIGTDHLDLDYLRRRGIAWASAPGCNARGVVDYVLGSLLSLAERQGVDLASRCYGVVGAGQVGGRLVEVLRGLGWRVLVCDPPRQALERGDFVDLPTLLRECDVLSVHTPLTHEGAHPTRHLFGREQLARLRPGTWLINASRGAVVDNRALREALAGRTDLQAVLDVWEGEPLVDVALAGLCHIATPHIAGYSLDGKLRGTAQVYRAFCEQQGVPPGVLLDELLPPPWLGELGLDGRADPAWALATLCRAVYDPRRDDADFRRSLEGDEQARRSAFDALRKHYPPRREIDGLRVRLSGEAPRLRQLVRALGAEPV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_XANAC
Sequence: MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHHLQVTDPVGLERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YCF12_HETA4
Sequence: MVNWQVIGQLLSATLIVLAGPAVIFVLAFKKGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RRG9_YEAS6
Sequence: MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
Protein: VPU_HV1H2
Sequence: QPIPIVAIVALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDVDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: RITA1_HUMAN
Sequence: MKTPVELAVSGMQTLGLQHRCRGGYRVKARTSYVDETLFGSPAGTRPTPPDFDPPWVEKANRTRGVGKEASKALGAKGSCETTPSRGSTPTLTPRKKNKYRPISHTPSYCDESLFGSRSEGASFGAPRMAKGDAAKLRALLWTPPPTPRGSHSPRPREAPLRAIHPAGPSKTEPGPAADSQKLSMGGLHSSRPLKRGLSHSLTHLNVPSTGHPATSAPHTNGPQDLRPSTSGVTFRSPLVTSRARSVSISVPSTPRRGGATQKPKPPWK
What is the function of this protein?
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway.  Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription.  May play a role in neurogenesis.
What are the official names of this protein?
RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the RITA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.
Protein: MTLD_BACLD
Sequence: MIALHFGAGNIGRGFIGALLCKSGYDVVFADVNDAVINELNDKGRYTVEMADAGRKQETIGPVRAINSATQLDELYDLIAKADLVTTAVGPAVLKLIAEPIAEGLKRRMKINKQPLNIIACENMIGGSAHLREEIFARLTETERAAISDSVGFPNSAVDRIVPIQHHDDPLKVTVEPFFEWAVDQTEFAGKVPDIEGVTYVADLAPFIERKLFTVNTGHAMAAYAGYKKGLKTIKDAIHHPEVRQTVAGALEETGRYLVQTYDFTQEEHRAYMTKIIGRFENECLSDDVTRVARSPLRKLGRDDRLVGPARKLCDLGFEPVRLAEGIALALQFDCADDPEAVQLQSMIAEKGYAGVLRDVCGLEEDHSLFKLVISHLKA
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: PD5BB_XENLA
Sequence: MALSKAKGNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKEQYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDCNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIVCEGDTVSQELLDSVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHSLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDLLLVNDQLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYSLQVEAGKESAKQISWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDTNAVKALNEMWKCQNMLRHHVKDLLDLIKKPKTEAGSKAIFSKVMVITKNLPDPGKGQDFLKKFTQVLEDDEKIRGQLEKLVSPTCSYKQAEVCVRDITKKLGNPKQPTNPFLEMIKFLLERIAPVHIDTESISSLIKLVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGNKIEEDFPHIRSALLPVLQQKAKKGSPRQAKYSIHCIHAIFSSKETQFAQIFEPLHKSLDPGNPEQLITSLVTIGHIAQLAPDQFTAPLKSMVATFVVKDLLMSDQLPGKKTTKLWVPDDEVSQETMVKIQAIKMMVRWLLGMKNNLSKSGNSTLRLLTAILHTDGDLTEHGKLSKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALVINDECYQVRQLFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVSEKLFSLLPEYVVPYTVHLLTHDPDYVKVQDIEQLKDIKECLWFVLEILMSKNENNSHAFIRKMVEYIKQTKDAQNPDDQKMNEKMYTVCDVAMNIIISKSTTYSLESPKDPVLPARFFTQPDKNFSNTKHYLPAELKSFFTPGKPKSTNVLGAVNKPLSSAGKQMQSKSSRMETVSNASSGSNPSSPGRIKGRLDSTELDQIEYEDYTMISSPLSGKKSDKRDDSDLLKSEVEKPRRGRKQPLIDPDDSFSMDELSKPAQEPKSRTSQRGRKRAAAASESEEQAWQEKRLKEDLLENEDEQNSPPKKGRRGRPPKSAKMAISKEEPPVTTPKRGRKNVVPIESPPTDEEDHLEISEEQDSENIDQKRKGRGSSKKTPQKSDSTDSALDTSRPTPQKRRGRPPKTPTVQQKKSHVGRPRKVVSKEPESEEEMEISQNSPALSENISNEEETADEEVVAPSTGRRRTAKKRRWIQRMKSELEGPLL
What is the function of this protein?
Plays a role in androgen-induced proliferative arrest.  Required for maintenance of sister chromatid cohesion during mitosis (By similarity).
What are the official names of this protein?
Sister chromatid cohesion protein PDS5 homolog B-B, Androgen-induced proliferation inhibitor B.
What is the protein family that this protein belongs to?
Belongs to the PDS5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANSME_BACTN
Sequence: MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEYINSQTMPQVLFTWHGGETLMRPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEFFRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGINLLKKHGVEWNAMAVVNDFNAEYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNFLCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHFVFPEYKLGNIYSQTLVEMMHSERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRTADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPANIMKALKDGSLKIEY
What is the function of this protein?
Involved in 'Ser-type' sulfatase maturation under anaerobic conditions.  Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract.  May catalyze the activation of chondro-6-sulfatase, i. e.  the post-translational modification of a specific serine residue into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM).  Is also able to oxidize a cysteine residue in a synthetic substrate to FGly in vitro, but not in a recombinant Cys-type sulfatase in vivo.  But since B. thetaiotaomicron possesses only Ser-type sulfatases, the oxidation of serine residues to FGly is the sole physiological activity.
What are the official names of this protein?
Serine-type anaerobic sulfatase-maturating enzyme, Ser-type anaerobic sulfatase-maturating enzyme, Anaerobic sulfatase-maturating enzyme, AnSME, Chondroitin sulfate/heparin utilization regulation protein.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
Protein: GPMB_SHIBS
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAARRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: AROL_ECO27
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_THEVO
Sequence: MTDSYDKLLEKAKDVLSSSTKNIDRLKIPEPEIIREGKATIIRNFQDIIDIINRDPDQVIKFLTRELGTNIVQNGRRLIINKKVTLEELQEKMNEYINTYVRCYECGSLDTEIQKSGRVSLLVCKACGAQHPIHTVKEFKEEEGIEEGKEYTVEISEVGSSGEGRASFRGFTIFVPGTKKGETVKVKIKKIKNDVAIAEVVSRTSDKK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: PERQ_SEDLI
Sequence: QTLQTSSQSQFHGLKFSHASSFKSPSAPLRKNSIFAKVTKGSTPPPFTLKDQEGRPVSLSKFKGKPVVVYFYPADETPGCTKQACAFRDSYEKFKKAGAEVVGISGDSSESHKAFAKKYKLPFTLLSDEGNKVRKEWGVPSDLFGTLPGRETYVLDKNGVVQLVYNNQFQPEKHIDETLKLLQSLK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin Q, chloroplastic, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin Q.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: TPM_SCHJA
Sequence: MDGIKKKMIAMKLEKENAMERAVQYEELLKKKEEEREKRENEISELNTKMKQAQIDCDEVQETLQEQMNKLEETEKRATNAEAQVAAMTRRIRLLEEDLEVSSSRLTETLTKLEEASKTAEESERGRKDLEIRSIADDERLNQLEDQQKEAKYIAEDADRKYDEAARKLAIAEVDFERAEARLEAAESKIVELEEELRVVGNNMKALEISEQESAQREESYEETIRDLTERLKAAEQRATEAERQVSKLQNEVDHLEDDLLAEKERYKALSGELDQTFAELTGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: FDHE_ECOHS
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKDPKIEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_GLUDA
Sequence: MSESQSEFPGGGTTGDIVRTMQEAQERAAVLAQALPFLRRYAGDTIVVKYGGHAMVDDSLSNAFGHDIALLKLVGVNPVIVHGGGPQISAMLTRLQIPSTFVDGLRVTDAAMVDVIEMVLAGKVNKQVAGLINQAGALAVGISGKDGGLITARRLQRTTRDASGQERALDLGFVGEPTHIDPRVLYALSGSGLIPVVAPVGIGEAGETYNINADTAAGAIAGAVHATRLLMLTDVPGVLDETGALIPELTAEEARRGIASGMISGGMIPKVETCLEAVRSGARAAVILDGRVPHACLLELFTEAGPGTLIRGE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPH_XENTR
Sequence: MLLRFYFNGLLFVGCLLSWGRSDTEEQCHTFTDLNIHNSIIGTGLKVQLLLYTRENPKCAQDLNVDNSTGFQYLNVTRRTVFITHGYRPTGSPPVWIDDIVKKFLDIQDFNVIVVDWNRGATTVLYHNAAANTRKVADILKRFIDNMLSQGATLDSIYMVGVSLGAHISGFVGKMYNGSIGRITGLDPAGPLFNGKPPEERLHYTDAQFVDVVHSDTDGLGYKESLGHIDFYPNGGTDQPGCPKTILAGSEYFKCDHQRSVFLYIASLTKSCDLVAFPCKSYRDYRIGNCTDCKEFLPLSCPVLGFYADKWKDHLVKRNHPGTTAFFDTAAKDPYCIFHYYLDFMTWSSQIRRGYITIKLTSLDGNVTESKLDKDAAVFEQYKEESLLAKFDQDMDPISRISVTFTTGSVIGPKYKLRVLRMRLRPFTNRNRPILCRYDFVLLENIETEFIPIPCEDTNL
What is the function of this protein?
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid (By similarity).  Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG) (By similarity).
What are the official names of this protein?
Lipase member H.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein.
Protein: MINC_LISMO
Sequence: MKKNVQIKGTKDGISIFLSDKASISELQQELTQLLADQKQNPYSGEKLEVQVQIGNRLFSEEEELEISTIIHENSQMEISAFYSNVMSKDEAKKWKENDQIFSMATIIRSGQVVQVPGDFLLIGDVNPGGQIRSNGNVFVLGNIKGIIHAGFEGNENAVVAGKFLYPSQVRIADKVYGFDSEDYKEVTETDLFSAFVNDAGEIVIDGIHKIRKIRPEISNFQGGR
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization (By similarity).
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: HUPF_RHILV
Sequence: MCIGIPMRVVVGSEFIAQCERHGAISSISLMLVGPQAPGTHLLTHLGSAIRVLDADEARAIDDALAGLAEAVEGRAFDMLFADLISREPELPPHLRGE
What are the official names of this protein?
Hydrogenase expression/formation protein HupF.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.