PharMolix/UniProtQA huggingface dataset:
Protein: SUVH5_ARATH
Sequence: MVHSESSILSSLRGGDGGGIPCSKDELAINGSYTDPMGRRKSKRFKVAAESEFSPDFGSITRQLRSRRMQKEFTVETYETRNVSDVCVLSSQADVELIPGEIVAERDSFKSVDCNDMSVGLTEGAESLGVNMQEPMKDRNMPENTSEQNMVEVHPPSISLPEEDMMGSVCRKSITGTKELHGRTISVGRDLSPNMGSKFSKNGKTAKRSISVEEENLVLEKSDSGDHLGPSPEVLELEKSEVWIITDKGVVMPSPVKPSEKRNGDYGEGSMRKNSERVALDKKRLASKFRLSNGGLPSCSSSGDSARYKVKETMRLFHETCKKIMQEEEARPRKRDGGNFKVVCEASKILKSKGKNLYSGTQIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDDGGELVATSIVSSGGYNDVLDNSDVLIYTGQGGNVGKKKNNEPPKDQQLVTGNLALKNSINKKNPVRVIRGIKNTTLQSSVVAKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPWKEVAKSKKSEFRDGLCNVDITEGKETLPICAVNNLDDEKPPPFIYTAKMIYPDWCRPIPPKSCGCTNGCSKSKNCACIVKNGGKIPYYDGAIVEIKPLVYECGPHCKCPPSCNMRVSQHGIKIKLEIFKTESRGWGVRSLESIPIGSFICEYAGELLEDKQAESLTGKDEYLFDLGDEDDPFTINAAQKGNIGRFINHSCSPNLYAQDVLYDHEEIRIPHIMFFALDNIPPLQELSYDYNYKIDQVYDSNGNIKKKFCYCGSAECSGRLY
What is the function of this protein?
Histone methyltransferase.  Methylates 'Lys-9' of histone H3.  H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Protein SET DOMAIN GROUP 9, Suppressor of variegation 3-9 homolog protein 5, Su(var)3-9 homolog protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: KGUA_PHOLL
Sequence: MIQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAMRPGENQGEHYFFITEEAFRQMIDNNEFLEHARVFDNYYGTSRKVIEETLASGVDVFLDIDWQGAQQIRKKMPSARSIFILPPSKEELCRRLRGRGQDSEDIIEKRMDQAVAEMVHYNEYDYLIVNDDFNTALADLHTIIRSERLHRERQAQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_BART1
Sequence: MARYVFITGGVVSSLGKGIAAAALAALLQARGYRVRLRKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRSANSQDNITTGRIYRNIIERERRGDYLGATVQVIPHVTDEIKRFITTGNEEFDFVLCEIGGTVGDIEAMPFLEAIRQLGNELSRQNVIYIHLTLMPFIPSAGELKTKPTQHSVKELQSVGISPDILLVRADRSIPETERCKLSLFCNVRANAVIQALDMPTIYDVPMAYHKEGLDSEVLCAFGIDSAPPPQMDLWEDITHRIHHPEGEVTIAVVGKYTGLKDAYKSLIEAIAHGGLANKVKVNIEWIDSQLFEKENSVLALQKAHGILVPGAFGARGAEGKIRAIQFARERKIPFLGICFGMQLACIEAARNIAQIENASSSEFCETENPIVGLMTEWLKGDVLEKRTRNGDLGGSMRLGAFAAELKEESHIAKIYGMTKIVERHRHRYEVNIDYKDKLEQCGLIFSGMSPDGVLPETIEYVDHPWFIGVQYHPELKSRPFDPHPLFSSFIEAAVEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MCC09_ARATH
Sequence: MENHQKTSFTFEIENFSERKYLIWSPIFISGQCHWFVKVYPIKDNNYDHVSVYLHVANPQSLRPGWKRRAHFSLILSNQSGKEVKIPSDSCDLFCTELSSSYPKILPPIKLKEEGFLENDKLIITVEVKVVEVVHPGELTGKEMVEFKELQDLYNGVQQNKEVVKNCELMNMDMKQDSLKSNHHEVSLKDKKRDDADESRFQKLEERLKNLELMELDCLKSKLEEVSIKNKKADADRSRVQRLEERLKNLELMDLDCLKSKLELVSIKNKKADADRSRIQRLEERVKKLELMELDDLKSKLEEVSLERKKSDDAYRSRVYQLEECFKNLELMVLDFKVELDKKKDKSCDDGFLLVDEFA
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At2g42475, RTM3-like protein At2g42475.
Protein: ISPG_HAMD5
Sequence: MYNLSSIIRRKSTRIYVGKVPIGENAPISVQSMTNTKTTDVAATVAQIKALQSVGADIVRVSVPTMEAAEAFNQIKQQASVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGSELRIRDVVASARHHGIPIRIGINGGSLEKDIQEKYKEPTPEALLESAMRQVSFLERLNFDQFKISVKASDVFLAIHSYRLLATRIDQPLHLGITEAGGARSGSIKSAIGLGILLSEGIGDTLRISLAADPTEEIKAGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEKRLEDIVTPMDVSIIGCVVNGPGEALVSTLGVTGARNKSGFFEEGERKGRLDNQQIIDQLEAKIRAKAALLDKKNRIQINQL
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: DPO3A_BACSU
Sequence: MSFVHLQVHSGYSLLNSAAAVEELVSEADRLGYASLALTDDHVMYGAIQFYKACKARGINPIIGLTASVFTDDSELEAYPLVLLAKSNTGYQNLLKISSVLQSKSKGGLKPKWLHSYREGIIAITPGEKGYIETLLEGGLFEQAAQASLEFQSIFGKGAFYFSYQPFKGNQVLSEQILKLSEETGIPVTATGDVHYIRKEDKAAYRCLKAIKAGEKLTDAPAEDLPDLDLKPLEEMQNIYREHPEALQASVEIAEQCRVDVSLGQTRLPSFPTPDGTSADDYLTDICMEGLRSRFGKPDERYLRRLQYELDVIKRMKFSDYFLIVWDFMKHAHEKGIVTGPGRGSAAGSLVAYVLYITDVDPIKHHLLFERFLNPERVSMPDIDIDFPDTRRDEVIQYVQQKYGAMHVAQIITFGTLAAKAALRDVGRVFGVSPKEADQLAKLIPSRPGMTLDEARQQSPQLDKRLRESSLLQQVYSIARKIEGLPRHASTHAAGVVLSEEPLTDVVPLQEGHEGIYLTQYAMDHLEDLGLLKMDFLGLRNLTLIESITSMIEKEENIKIDLSSISYSDDKTFSLLSKGDTTGIFQLESAGMRSVLKRLKPSGLEDIVAVNALYRPGPMENIPLFIDRKHGRAPVHYPHEDLRSILEDTYGVIVYQEQIMMIASRMAGFSLGEADLLRRAVSKKKKEILDRERSHFVEGCLKKEYSVDTANEVYDLIVKFANYGFNRSHAVAYSMIGCQLAYLKAHYPLYFMCGLLTSVIGNEDKISQYLYEAKGSGIRILPPSVNKSSFPFTVENGSVRYSLRAIKSVGVSAVKDIYKARKEKPFEDLFDFCFRVPSKSVNRKMLEALIFSGAMDEFGQNRATLLASIDVALEHAELFAADDDQMGLFLDESFSIKPKYVETEELPLVDLLAFEKETLGIYFSNHPLSAFRKQLTAQGAVSILQAQRAVKRQLSLGVLLSKIKTIRTKTGQNMAFLTLSDETGEMEAVVFPEQFRQLSPVLREGALLFTAGKCEVRQDKIQFIMSRAELLEDMDAEKAPSVYIKIESSQHSQEILAKIKRILLEHKGETGVYLYYERQKQTIKLPESFHINADHQVLYRLKELLGQKNVVLKQW
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD_LIMRJ
Sequence: MSTHINAKMGDYADTVLLPGDPLRAKYIAENFLENVKQVNSVRNAFGYTGEYKGHRISVQGSGMGIPSMSIYINELVREFGVKTIIRVGSCGGIAPDVHVRDVLLAQGSSTDSAVTVNTFGPGFHYAPLADFKLLDTAYHVAGKLGIETKVGDIFAADRFYNDELDMEKLRDYGILGTEMESAGLYLLAAKLHFRALSVLTVSDLIFGDEKATAEERERTFNDMINISLETAIAGK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: METK_LISMO
Sequence: MAKNRHLFTSESVSDGHPDKIADQISDAILDAIISKDPDARVACETTVTTGLVLVAGEITTSVYVDIPKIVRDTIKEIGYTRAKYGFDAETCAVLTAIDEQSPDIAQGVDEALESRSGNEIDAAIEAIGAGDQGLMFGFATDETEELMPLPIFLAHGLARKLTELRKTNKLDYLRPDAKTQVTVEYDEFNQPVRIDTIVVSTQHHPDITQEQIAKDLHTYLFPEVIDASFLDEDTKYFINPTGRFVIGGPLGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNIVAAGLAKKVEVQVAYAIGVARPVSISIDTYGTSDYSEQELIDGVNALFDLRPAGIIHMLDLRRPIYRQTAAFGHFGRSDLDLPWERTDKAEALKKLIVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ENDTX
Sequence: MDKLSSKIRAEFLGFFKNSGCAVVPSDSLIPAGDKTLLFTSAGMVQFKQHFLGQSKDSFTRATSCQKCFRTSDIDQVGTTARHLTFFEMLGNFSFGDYFKKEAAAWAWEFLTKNMSLPKDKLYITIYKDDDEVAGIWKNIAPANKIIKMDEKTNFWNMGETGPCGPCSEILIDLGQETGCGSPACCPECNCDRYLEIWNLVFTQFDKQPDGSLKNLPRKNIDTGMGLERLSATVNGRKNVFDTDLFMPVMENAAEILKIKNEGSNISKLRMIADHSRAITFLISDGILPSNEGRGYVLRRILRRALRQGKFYGYNKPYINELVSDVLKIMEGAYPELSSKLSNIRSIVKTEEEKFLETLESGSEILSSLINSYKSKDINIISGKDVFKLYDTYGFPHDLTKEMAFENGLEIDEDKFKFEQKKAQEKSRVAWCGSGERDITFYSILRKKTGDTVFTGYDNYASESRVLALIKDGSEISELKTGDNGEIILSHSSFYAQSGGQSDDKGKIANNSFESIVEYIFKPAGNLFVHKVKVLKGLIKINDAVSTIIDIERRKQIARHHTAAHLLHKALREAFGGHITQAGSLVARDYFRFDFTHFSALKKDDLIKIEKRVNSIIRLNSEVCIETMAIAKARNAGAMALFGEKYGDEVRTVLIKNESGDGNYSMELCGGTHVSRTGDIGIFKIISESSAAAGVRRIEAVAGIAAENYILDEEAVIIKTSKILNASKEELVNKAHKYTSDYKKLENEFKSLKSSLISGEIDSYAKEVKKINGINFLSVIADKADIKALRTISDQLKEKLKSAVLLIVSKNEDRASFILSATADCVQKGINAGKIAKAFAASINGSAGGKPDFAQGGSKDLSNLNDAVKNAHKYILL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_NEIMA
Sequence: MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQVAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHEDVPFGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQFMLDTHTLKHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDESKTTQYLIPTAEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGATKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAALQPYMGGVAKLEVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC1_BIGNA
Sequence: MNYYSIQNSRDSSISSIEIRICSSKSIVKKSSRILPNGNIVGEIKTAQTMNYKTLKPENSGLFCEQTFGPIKDFECACGKKYENEFIGFCAICGIEYASSQVRRNRLGYIKLVSPVVHIWYLKYISILLDIPLKSIESIVYSTDGIIFKNFFQKPKKNQILKKETFEITENLNNTYFKDSINLKYSLHVQKNIISYLKNLKQAVFILKTKQDQQLKYNFSYLYYTLNNFYSLSYSFQWEAKKQWNTIIWFFKYKQRMKENFIKIDPLQKKLNDEYFEKTFLFGTSILYCWLKYFDYNFQLLNLERQIRFTVFEIKEEIKELSGILFSYFFQKQQFISFQKKIKKLNWKKNKVFRRLKLIMYFRQAKLQPKWMILSSLPVLPPDLRPIVELGSNKIAVSDLNKSYQTIILRNLRLKKFYNNSAFNEFTEEIRYTKRLLQESVDELIQQDKSKKNNNISSKSLSDILKGKRGRFRQNLLGKRVDYSGRSVIIVDPELKLHECGIPLKMAIELFYPFIIQYLISFNLTKTIPGAKHIIHTKASFLNEIIHFVLNNYLVLLNRAPTLHKLGIQAFKPKLVTGKAIKLHPLVCPAFNADFDGDQMGMHIPLSFESRAESWKLLWSRNNLLLSSMGSPILTPGQDVVLGCYYLTSNLLDKVKTYIKPCHLNKKGENWSIYFNNLNDVLKAYNQNKVNIHTEIWIKWSENIMFENNSLDLRRLEVYSGKFFRFQYENYQINYNLKGYQLSQYIKTTVGRVIFNSLLY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMPA_RICBR
Sequence: MLHVNFTEEESLNTQALIVFIDDKLKLDSELINLDQQHHGLISKTIANKLQFTGKYGQIKIIPSVVKSGEVKYLVLAGLGSEEKLTEVKIEELGGKILQNVTNAKIATIGLKIKNRISNFTSSHVASLIASGALLASYRFDKYRTTLKEADKFVVESFEISTDNNAEATKLFEVKKLIAEGVFFTRDISNEPSNIKTPQIYAERIADILEELNVDVSILGEREMKNLGMGALLGVGQGSQNESKLVVMEYQGANKDAPYIALVGKGVIFDTGGISLKPSNNMHLMRYDMCGSAAVVGTMIAVASQELPVNIVGVVGLVENMPSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAIVVSLGPTYAGCFSNNDELADKLIKAGEEVNEKLWRMPLHEDYDAMINSDIADMANIGNVPGAAGSSTAAHFIKRFIQEGVEWAHLDIAGVANSNKPSSLGPKGAVGYGVRLLEKFIKENYEQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGTP_SHIFL
Sequence: MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL
What is the function of this protein?
Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system).
What are the official names of this protein?
Alpha-ketoglutarate permease.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAG_HV1M2
Sequence: MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHIVWASRELKRFALNPGLLETTEGCKKIIGQLQPSLQTGSEELKSLFNTIVVLYYVHQKIEVRDTKEALDKLQEEQDKHQQKTQQATADKGVSKGVSQNYPILQNLQGQMVHQSLSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQIAWMTSNPPVPVGEIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQEVKGWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPSHKARILAEAMSKATGAAIMMQKSNFKGQRRIVKCFNCGKEGHIARNCRAPRKRGCWKCGQEGHQMKDCTERQANFLGKMWPSNKGRPGNFLQNRPEPTAPPAESFGFGEEIAPSPKQEQKDKEQVPPLISLKSLFGSDQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: PA24A_HUMAN
Sequence: MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA
What is the function of this protein?
Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response (PubMed:7794891, PubMed:8619991, PubMed:8702602, PubMed:9425121, PubMed:10358058, PubMed:14709560, PubMed:16617059, PubMed:17472963, PubMed:27642067, PubMed:18451993).  Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production (By similarity).  Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (PubMed:7794891, PubMed:8619991, PubMed:9425121, PubMed:10358058, PubMed:17472963, PubMed:18451993).  Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway (PubMed:18451993, PubMed:7794891, PubMed:9425121, PubMed:10358058, PubMed:17472963).  In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids (PubMed:27642067).  Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position.  This hydrolysis is not stereospecific (PubMed:7794891).  Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides (PubMed:12672805).  Has O-acyltransferase activity.  Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis (PubMed:7794891).
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane. Nucleus envelope. Note=Translocates to intracellular membranes in a calcium-dependent way.
Protein: PANC_GRABC
Sequence: MHLARTLPTLQQAVHQLRHAGKRIAFVPTMGALHEGHQSLVRAAIAQDYAVVTSVFVNPTQFGPSEDLARYPRDEKGDIAILERTGCSIAWLPDVDTMYPPGDATGFVMGGPALGWEGARRPGHFNGVAQVVAKLFGQVRPDAAFFGEKDWQQLQVIRRLTADLLLPVAIHGVPTQREEDGLAMSSRNRFLSPEERAIAPLLFRTLLQAGHALSSSPDAEEICKNAIAALNGQGFDVDYFALIEGSSLSSIAILPEGDDWRLITAARLGSVRLLDNLGRAELARFRA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDC_VIBCH
Sequence: MNPLLSAHCSCSQEIAQQFAHYQHISGEGEIYQTSLMSALIAGVYEGATTIAQLLEHGDFGLGTFNELDGELIAFDRQVFQLRADGSAQPAHPEQQTPFAVFTFFKADIELPITERMTREQVHQLIDRLVPSDNLFCAIRIDGTFPSVQTRTVPKQQRPYRPMLEVVKQQPVFRFQQQHGVIAGFRSPQYTTGINVPGYHEHFITQQRTGGGHIQDYIIRSGFLQIGRVSRLVVDTPVSRDFLEANLTPNNIRTAIEAAEK
What is the function of this protein?
Converts acetolactate into acetoin.
What are the official names of this protein?
Alpha-acetolactate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the alpha-acetolactate decarboxylase family.
Protein: GLPK1_CLOTE
Sequence: MAKYVMALDQGTTSSRCIIFNERGLIVSVAQREFKQIYPKGGWVEHDPMEIWATQFSVATEAMAKANIEASEIASIGITNQRETTIVWDKRTGLPVYNAIVWQCRRTAQICDELKEKGLTETIRNKTGLVLDAYFSGTKIKWILDNVAGAREEAEKGNLIFGTVDTWLIWNLTKGKVHVTDYSNASRTMIYNIHELKWDDELLEALDIPKSMLPEVKPSSYVYGETNSTLFGSSIPIAGVAGDQQAALFGQMCHQEGTAKSTYGTGCFLLMNTGEKAVKSENGLLTTIAFGIDDKVEYALEGSIFIGGAAIQWLRDELRMLKDSPESERYATAVEDTNGVYMVPAFVGLGAPYWDPYARGAIVGLTRGATKEHFIRATLESLAYQTYDVLNAMREDSGIDLKALRVDGGASANDFLMQFQADILGVPVQRPEVIETTALGAAYLAGLAVGYWKDKKDVAQNWAISKTFEPDMIKERREELLEGWHEAVKRSMNWEKSE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase 1, ATP:glycerol 3-phosphotransferase 1, Glycerokinase 1, GK 1.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PYRI_NEIMA
Sequence: METPKLSVEAIEKGTVIDHIPAGRGLTILRQFKLLHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDHFKVVQKRHLNLPDEIAEVFRCPNTNCASHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: ISF1_YEAS1
Sequence: MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKLASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTNNSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYGIPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPSSYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSSPLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESIPHTSNCLEERNPRRKSFIKLSLASSFSN
What is the function of this protein?
Could influence the NAM7/UPF1 function, possibly at the level of mRNA turnover.  Participates in mitochondrial biogenesis (By similarity).
What are the official names of this protein?
Increasing suppression factor 1, Mitochondrial biogenesis regulation protein 3.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
Protein: BTUF_YERPA
Sequence: MMPLGLFPLPRAAAVLLISLLTLPAQAAERVISLSPSTTELAYAAGLGDKLVAVSAYSDYPESAKKLEHVASWQGINVERILALKPDLILAWRGGNPQRPLDQLAALGIPIFYSDPTHIDQIASDLDKLAQYSPHPEQAHQAAEQFRQHVNTLRDRYARSQPKRTFLQFGTQPLFTSSGHTLQSEVVSLCGGENIFADSRVPWPQVSREQVMTRKPQVIVVSGTQSQVDNVSAFWLPQLVVPVIALNEDWFNRASPRILLAAQQLCQQMASIPTPVAESH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MPSB_MACPH
Sequence: MYIVSSKKVSRAPLHVASLCVTLHRLKCDRNQPCSTCSHRGLSFSCTYVASAANSVRKADQSRPSPRPAAGIQDRITQLEGLVLTLMHSVNHKPAPSTGAPESASVLDADLPASFGRISLENDETRYVSGDHWISILDGIAELKDHFEDDNLNAGASPAAGAATAEYQGPKLLFGCHSPTTRESILASLPQRPVTDRLVSKYFNSMDMASSIIHGPTFIREYETFWLAPSETPIMWIGLLFAVIALGTHFQQRETHFIHPSPQRHSVLEAYKDKVIECLVLGKYTKVGPYAIETLMLYFSLEHLPAADTRVDNWILVGIIVRLAMRVGYHRDPSHTPQIKPFQAEMRRRHWATIVQLDLMTSTQVGLPRMVNEAVCDTVEPRNLLDQDFDDQVVDLPPSRPDSDMTSILYLNARNKLMTVFGMITDLTTSTFPTSYRHVMRLDRTLHNTVAAIPSGLQLKALSQSITEPSETILRRIYLDMTFHKARCILHRKYLTAAQVNASYIYSRTSCIDAAVRILQHQDVLFRECQPGGLLHSGNWKITSVLNHDFLLAITILSLDLNGAMELASKSQLIETPMEQQRRENIIRSLNRSYNIWLQSANTSREARKAAEVLRIVLAKAQNSSISTPSHDQDDLDGEAATEATESEYMNSPLTLQPFLACDPGASTAIGTNICTTLDVASPSDYMEDLNDNVTSGVDFDWDNWDSHFRGQNTPNMSTMDLRFPNLDYPTDGRGSDGCI
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of macrophasetins, 3-decalinoyltetramic acids (DTAs) which feature a tetramate (pyrrolidine-2,4-dione) unit connected to a decalin fragment and that have potent bioactivities.
What are the official names of this protein?
Zn(2)-C6 fungal-type transcription factor mpsB, Macrophasetins biosynthesis cluster protein B.
Protein: RK20_LOBMA
Sequence: MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHEMGVFYSYNEFIHNLYTKQLLLNRKILAQIALLNRSCLYTISTEIKN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.