PharMolix/UniProtQA huggingface dataset:
Protein: COX2_CHOBI
Sequence: MATWSNFNLQNSASPLMEQIIFFHDHTLIILIMITILVGYLMISLFFNSYINRFLLEGQMIELIWTILPTITLIFIALPSLRLLYLLDELNNPLITLKSIGHQWYWSYEYSDFQNIQFDSYMIPINEMKNNNFRLLDVDNRIILPMNNQIRILVTATDVIHSWTIPSLGVKVDANPGRLNQTNFFINRPGIFYGQCSEICGANHSFMPIVIESISIKNFINWINNYS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CSRA_METCA
Sequence: MLILTRRVGETLMIGDDVTVTVLGVKGNQVRIGVNAPKDVSVHREEIYERIKKEQQAGPEHDSD
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_SPIOL
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNRICFGRYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTVRPAETRMGSGKGSPEYWVAVVKPGRILYEISGVAENIARRAVAIAASKMPIRTQFIISG
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic, Chloroplastic large ribosomal subunit protein uL16c, Ribosomal protein CS-L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGJ_DEBHA
Sequence: MQLNGIGKHSIRFLSDKASRFVPKGGVYPKGFMVGGIHCGVKKDGKSLDLAILTNTHGKSAVASAVFTTNKFKAAPVQVSSKIVKEKKGEEINSLVVNSGNANAVTGSQGMKDAQDMITVTDSALGNPTNSSLVMSTGVIGNNLPISKILSGIPQLAGGNLGNTHEDWLNCAQAICTTDTFPKLVSKSFELNGHTYTLAGLAKGAGMICPNMATLLGFFVTDAPVSASALDQILKFATDRSFNSISVDGDMSTNDTIVAIANGAAGGELIDNTASSAESFGILQREITGFAQQLAQLVVRDGEGATKFITISVKNALSYGDAKIIASSIANSSLFKTAMYGNDANWGRILCAIGYSQVSSGDSINPAKTNVSFIPSDGSSKLKLLVNGEPEVVDEKRASEILSVEDIEVEIDLGTGGGQECKFWTCDLTHEYITINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DEOC1_VIBVY
Sequence: MNHYIDHTLLLANATTKQINTLCDEAHEHQFFSVCINPDFVEHCAERLNTSNVKICTVIGFPLGANTTAVKVFETQNAISLGADEIDMVVNISDVLDGKWDVIEKEIVAIKEACGPKLLKVIFETCLLTNEQIVKLCNISKRAGADFVKTSTGFSTGGATVEHIKLMRDTVGKQMGVKASGGVRTKETAQAMIDAGASRVGASASVSIVTGEAPTTNGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 1, DERA 1, 2-deoxy-D-ribose 5-phosphate aldolase 1, Phosphodeoxyriboaldolase 1, Deoxyriboaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAS1_PIG
Sequence: MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI
What is the function of this protein?
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response.  In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation.  Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation.  Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication.  Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.  The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
What are the official names of this protein?
2'-5'-oligoadenylate synthase 1, (2-5')oligo(A) synthase 1, 2-5A synthase 1, p42 OAS.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Secreted. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
Protein: FAHD2_MESAU
Sequence: RALATQLPVIPRSQVTFLAPVTRPEK
What is the function of this protein?
May have hydrolase activity.
What are the official names of this protein?
Fumarylacetoacetate hydrolase domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: MENC_YERPN
Sequence: MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQVAAECWLQHWVSGVESDDSVLPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFAVLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLRLDANRSWSRAKADGFAKYVNPALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLVGSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQVVRPWPDSPLPLITTEQLGVVWHR
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: COAD_BACCZ
Sequence: MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_ECOL6
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHNIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RF2_MYCTU
Sequence: MDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPHLWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAAADAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMRVLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_PERMH
Sequence: MHTIKTVLLLGVLTGLFLLAGKIIGGQTGMIIAFFFAMAMNFFAYWFSDKMALKMYRAQEIPYEEAPWLHDMVAELARNAGIPKPRIYLAPTEIPNAFATGRNPKNAVVAVTSGILNILSPEELRGVLAHEIAHIKNRDILISSIAATIGGAISMLAEMAFWSNIFGGNDEDNGIGGLIGSLLLFILAPIAAMIIQMAISRSREYAADATGAEICRCPLSLAKALEKLEMAAHQLAPVAAREVNPGTAHMMIVNPLKGSSIASLFSTHPPTEERIRRLYEMARRMGSV
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRA12_HUMAN
Sequence: MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGASALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGTLDECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACCQGGFI
What are the official names of this protein?
PRAME family member 12.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: RECF_RHILO
Sequence: MPAQTHISKLTLTNFRNYAALAIDLAPGAVVFSGDNGAGKTNLLEAISLLTPGRGLRRAPYADVAREGGDGGFALHARLDGPDGQVEIGTGISVGEGEGGRRVRINGATARSAEDMLEWLRVVWLTPAMDALFTGPAADRRRFLDRLVLAIDPGHGQRALDYEKAMRGRNRLLTDGSRDDRWFEAIETQMAETGVAIAAARAELVRLLAAMIDRLPDTGPFPQADISLSGDLEAEVSSAPAVDVEERFRRALAGGRDRDRAAGRTLEGPHRSDLLVRHRPKAMPAELCSTGEQKALLVGIVLSHARLTGEMSGMTPILLLDEIAAHLDGGRRAALFSILEELNCQAFMTGTDAALFSSLMGRAQFLTVDHGTVGPTEDA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BURO0
Sequence: MAKISKRRQAFAAKVDRQKLYAIEDALSLVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEIVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRSNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDHATLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DNA2_CHICK
Sequence: MADPSNAALRSGLNNRYRVLEVRVVRGEGRDPEKHLAVSSDPSLGDTELCVLQNGWESVPVVPGDIVHLEGDCSSGTWVINEQSGYLILYPDLLLSGTTISSSIRCMRKAVLSERFRGSECGSRQTLVGTILHEIFQQSVTNNLSPEKVEELAKKIVYGQKYLKEMYHLKLKQTEIMQEIEEYLPSFFKWTEDFVRNPANQNKMQLKLPSENKTGDCSSTVEIVDILDIEENIWSPRFGLKGKIDVTARVKIHRQGGIQSRIMPLELKSGKESNSVEHRSQVILYTLLNLERRVDPEAGFLLYLKTGTMYPVTGTRMDRRELIKLRNQVAFYLMHSTYKSAVGRQQSQLAALPPLIDDSQACKYCSQIHNCFLYSRAVEERMASVSFPPALIPIIEKETQHLKPSHLEYFSLWYLMLTLEMQSGDSKKGYKNIWMIPSLEREKAGDCVGNMIRVDQVQEVSEGQYLHSFQRKNGAVPGANLLVGDRVVVSGEENGLLGLATGYVREISATKISCLLGRNLSKLPESTTFRLDHEEGDCSIGVPFENLSKLMKDSPVSEKLRNLIIDFHKPRFIQHLSSVLPPEAKEAVASILKGLNKPQKQAMKQVLLSRDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVGFLRLGRAQKVHPDIRKFTEEEICRSKSIKSVTDLEELYNSQPVVATACMGINHPIFVQKQFDFCIVDEASQISQPICLGPLFCSKRFVLVGDHQQLPPLVQNSEARDLGMSESLFKRLEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEKVSNATANLPNLKMLKLEFADASKTWLKEVLEPDKPVCFLNTEKAGCRPSDIGIISPYRHQLKVITDLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGALLKDWRRLNVAITRAKHKLIMVGCVPSLRRYPPLEKLLCHLQSEAMIFNLPPGAHESIHKCNIL
What is the function of this protein?
Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion.  Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1.  Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by the presence of RPA.  Also involved in DNA replication checkpoint independently of Okazaki fragments processing.  Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities.  While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is subject to debate.  According to various reports, the helicase activity is weak and its function remains largely unclear.  Helicase activity may promote the motion of DNA2 on the flap, helping the nuclease function (By similarity).
What are the official names of this protein?
DNA replication ATP-dependent helicase/nuclease DNA2, DNA replication ATP-dependent helicase-like homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: GLGE_METI4
Sequence: MKMPSFGYEVEKSFLPVDGRKRIVIERIFPSVDCSDFPLKRVIGQTMVVRAYVFADGHERISVHLAYRHIADSQWTEISMEELGNDEWEASFPLEKLGIYEVKIIGWIDHFQNWLEKLHKLAENDKDIAVELSIGIGLLEKNWAFSRSQELKDWIDRLKDERLSLHQRLQLIKNPYLEELVQKNPDRSLSVESESPLFIFVERSKAQFSSWYEFFPRSWSSVPGKHGTFKECERLLPDIAAMGFDVVYLPPIHPIGKKARKGKNNALIASPEDVGSPWAIGSAEGGHKSIHPSLGSLEDFRHFVKKAADYGIEVALDIAFQCSPDHPYLLEHPAWFKWRPDGTVQYAENPPKKYEDIVPFDFETEDWQALWEELKSIFVFWINQGVKIFRVDNPHTKPLAFWRWVIWEIKRDYPDTLFLSEAFTRPKLLYGLAKRGFSQSYTYFTWRSEASEIKAYMEELTSPPVVEFFRPNFWPNTPDILAGYLQYAPPSVFKMRHVLAATLSSNYGIYGPAFELCVNIPLEPGKEEYKDSEKYEIKTWDWNAPGNIKEFIAKVNHIRKLHPALQRTENIRFIQGDNPRLLAYVKELPGHGDPLLIVVNMSRNTEMGWIHFQPESVGLDPSKPYQLTDLLADVTYTWHGEWNFVKLDPEACPAHLFQLSQDGSFSP
What is the function of this protein?
Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
What are the official names of this protein?
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, GMPMT, (1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
Protein: PRDA1_ARATH
Sequence: MLQSIHLRFSSTPSPSKRESLIIPSVICSFPFTSSSFRPKQTQKLKRLVQFCAPYEVGGGYTDEELFERYGTQQNQTNVKDKLDPAEYEALLKGGEQVTSVLEEMITLLEDMKMNEASENVAVELAAQGVIGKRVDEMESGFMMALDYMIQLADKDQDEKRKSLLEVVKETVLSHLTKKCPPHVQVIGLLCRTPKKESRHELLRRVAAGGGAFESENGTKLHIPGANLNDIANQADDLLETMETRPAIPDRKLLARLVLIREEARNMMGGGILDERNDRGFTTLPESEVNFLAKLVALKPGKTVQQMIQNVMQGKDEGADNLSKEDDSSTEGRKPSGLNGRGSVTGRKPLPVRPGMFLETVTKVLGSIYSGNASGITAQHLEWVHQKTLQVLEEIAY
What is the function of this protein?
Plays an essential role in early steps of chloroplast development.  May be involved in the redox control of plastid gene expression by maintening the redox state around chloroplast nucleoids.  May positively regulate plastid-encoded RNA polymerase (PEP) activity, through binding to FSD2.
What are the official names of this protein?
Protein PEP-RELATED DEVELOPMENT ARRESTED 1, chloroplastic, AtPRDA1.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma, chloroplast nucleoid.
Protein: FLL1_GLUDI
Sequence: SLSINTNTSEMIALQTLDA
What are the official names of this protein?
Flagellin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_COXBU
Sequence: MIQTQSIVDVADNSGARRVMCIKVLGGSKRRYANIGDVIKVSIKEAIPRGKVKKGDVMHAVVVRTRKGVRRNDGSLIRFDNNAVVLLNNQLQLVGTRVFGPVVRELRTDKFMKIISLALEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RS2_HYDCU
Sequence: MAKVTMRQMLEAGVHFGHQTRYWNPKMGEYIFGARNKIHIVNLEKTLPMFNDALNFLGGIAAKKGTVLFVGTKRAAGDLVAQEAKRCGMPYVNHRWLGGMLTNFKTIKQSIKNLKDLEVQEQDGTFEKITKKEALMRSRQKAKLELSLGGIKDMRAMPDAIFIIDTGNEKIAIQEAKNLGIPVVGVVDTNNDPNGVDYVIPGNDDAVRAVSLYLSAAADAINEGKGSITTAVEGDEFVEEKAEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GYRB_MICLC
Sequence: MVDAMPENPAEEPTAASAAPNPEAVPDAVGQPEAPVKDRKVPGEYGASAITVLEGLEAVRKRPGMYIGSTGPRGLHHLVYEVVDNSVDEALAGYATGIDVTLQADGGVRVADDGRGIPVDLHPTEGRPTVEVVMTILHAGGKFGGGGYAVSGGLHGVGISVVNALSRRVDTEVRRQGHVWRMSFADGGVPQGELVKGEATDATGTVQTFYPDAEIFDSIEFDYETLRARFQQMAFLNKGLRITLTDERVQESNEVVDDEIAGEGAAGEDVAENGLAEDAEQEPQRRSVTYLYENGLLDYVQHLNSAKKVEYVHDDVIAFEAEDFSDGRSMAVEVAMQWTSAYSESVHTYANTINTHEGGTHEEGFRAALTSLVNRYAREKEILKPKEDNLSGEDIREGLTAVISVKLSEPQFEGQTKTKLGNSEARGFVSKAVTDHLGDWFERNPGPAKEIIRKAIMASHARLAARKARDNARRKSPLESFGMPGKLADCSSKDPERCEVYIVEGDSAGGSAKQGRNPETQAILPLRGKILNVERARLDKALGNAEIQSMITAFGTNIGEEFDISKLRYHKIVLMADADVDGQHITTLLLTVLFRYMRPLIEAGHVFLAQPPLYRIKWSNAPHDYVFSDEERDAAVEAGLAKGWRYPKDNGVQRYKGLGEMNYQELWDTTMDPEHRTLLQVTMEDAAAADAVFSMLMGEDVESRRTFIQQNAKDIRFLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_XYLF2
Sequence: MTTFTAKNETVQRDWYLVDAEGKTLGRLATELARRLLGKTKPVYTPHVDTGDYLVVINAEKVVVTGKKLTDKYYHRFTGYVGNLKSESLGQALQRHPERVLEIAVKGMLPKGPLGRAMYRKLKVYTGSKHPHTAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RSMG_BACHK
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFEIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVREAYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGDLKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_BURP1
Sequence: MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTPDQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQMQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLGGIAPALAKKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.