PharMolix/UniProtQA huggingface dataset:
Protein: KAD_CLOBH
Sequence: MRIILLGPPGAGKGTQAKLISEEFSIPHISTGDIFRANIKEKTPLGIEAKRYIDNGQLVPDEVTIGIVKDRLTKDDCDNGFLLDGFPRTVAQAEALDEFLKGINKELDVALLIKVPEEFILERMTGRRVCTSCGASYHIRFNPPKIEGKCDICDNELIQRKDDTEATVKERLEVYSKQTYPLINYYKDNGIISEVNGTESINEVFGNISNILGRDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATR4_STEAL
Sequence: MEDPKSLSAPLTAFNADTTTADETPAAQKKYEDDNGQKAGSESSENTKNSDHGDATEVNTPKSADLEANALRNSSVSRSNQEQEKSEEAIDPNIVDWDGPNDPSNPLNWPTWKIKTHIFLVSSITFISPLGSSILATGIPQILAEFRSTNAELGSLVVSVYLLGFAAGPLVIAPLSELYGRMPLYHICNILFAILTVGCALGPTLNSEIGLRFLQGCAGSAPLAIGGGTISDLIPQERRGKYMGIYALGPTLGPIFGPVAGGFLTGAKGWRWLMWLLLMIEGSVTLVNFVVMRETYGVVIMARKTRALQKQTGNMSLRSRYDQGLTTRRLWRNTLIRPAKMLVYSPIIFLLSLFMAMVYGYLYLLFTTFPVVFGEYYHFSIGITGLVYLGLGIGNIIGLVIFGVFSDKILLAKAASGELKPEYRLLPMVWTSFTVPIGLFIYGWSARYAVHWIVPIIGTVFFGIGLLVTLVCTLTYIVDAFTEYAASATAANAVMRSVVGATLPLAGPSMYQALGIGWGNSLLAFIALAGCPIPWVFYVYGERIRKSSKATY
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of atranorin, a depside of polyketide origin that accumulates in the cortical or medullary layers of lichen thalli.
What are the official names of this protein?
MFS-type transporter atr4, Atranorin biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU6M_SCYCA
Sequence: MVYFVSMMMIGLILGLMGVASNPSPYYAALGLVTAAGVGCGLLVSYGGSFMSLILFLIYLGGMLVVFAYTAALAAEPYPEAWGDWSVLMYVGIYLTGLVIAGKYFLVGKWGDSWAGVEELSSFEVVRGDFGGVALLYSLGGWMLVLSGWVLLVTLFVVLEVTRGLSWGTLRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SHC3_HUMAN
Sequence: MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGEALRKAPDDGPGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPSAPRAPAMSAARKGRPGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPPPGGFLDTRLKPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYSTPEGKLHVAPTGEAPTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ
What is the function of this protein?
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons.  Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
What are the official names of this protein?
SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3.
Protein: YIDZ_SHISS
Sequence: MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSRELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHETWNLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: F220A_RAT
Sequence: MRAGRGTLGVCLASVKQSQGGDLDKLACGLKRRSEKRNPSPSDVPSWTDQPVADTHGKSRAMAAASSEMKRDQSKASLILHSGFKALQYLKESMGRNSTPAASLSMAVVLSSAPSEEHGAGVSGGIGDTLGSDWPAREPRTTDSCGQYLKGEAWVSGWQGHPKVREVGFLRGEPLSAVPKGLGTRSELSYCSELCQLPYTYPYYEALPEDKTRCVSLDHLSPVFSEETVEDEKTLSSTSDGLQIVMGLLALQSSRLTSL
What is the function of this protein?
May negatively regulate STAT3.
What are the official names of this protein?
Protein FAM220A, STAT3-interacting protein as a repressor.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_PSEE4
Sequence: MSQPIVVAALYKFVTLEDYVELRDPLLKAMTDNGVKGTLLLANEGINGTVSATREGIDALLAWLRNDPRLVDVDHKESYCDEQPFYRTKVKLKKEIVTLGVPGVDPNKAVGTYVDPKDWNALISDPEVLLIDTRNDYEVAIGTFKGAIDPKTETFREFPDYIKANFDPSKHKKVAMFCTGGIRCEKASSYMLGEGFEAVYHLKGGILKYFEEVAQEESLWDGDCFVFDNRVTVRHDLSEGEYDQCHACRHPIDVKDRESEHYSPGVSCPHCWDTLSEKTRRSAIDRQKQIELAKARNQPHPIGYNYKAEA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RLMN_NITHX
Sequence: MAVGDAPLEKVALETYVPPAKPSLIGLSRAEISERLAAIGVAPAQRRMRVQQLWHWMYVRGAKTVGEMTNVSKDMRAELEKHVTVDRPEVVAEQISNDGTRKWLLRLPSGNTLEKPHEVECVYIPETDRGTLCVSSQVGCTLNCSFCHTGTQRLVRNLTAGEIVGQIMVARDRLNDWADRETPHGNRLVTNIVMMGMGEPLYNFDAVRDALLIVADNEGIGISKRRITLSTSGVVPNIVRTGEEIGVMLAISLHAVRDELRNELVPLNRKYPIAELMQACRDYPAASNAKRITFEYVMLKGVNDSLDDAKLLVKLLKGIHAKINLIPFNPWPGTRYECSDWEQIEKFSEYVFNAGYSSPVRTPRGRDILAACGQLKSETEKLSARERQALRAMAMTD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM8_CAEEL
Sequence: MDSADPQLNRFLQQLQAETQRQKFTEQVHTLTGRCWDVCFADYRPPSKMDGKTQTCIQNCVNRMIDASNFMVEHLSKMNGGHV
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane (By similarity).  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane (By similarity).  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).  The ddp-1/tim-8-tim-13 complex mediates the import of some proteins while the predominant tim-9/tin-9. 1-tim-10/tin-10 70 kDa complex mediates the import of much more proteins (PubMed:15485840).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim8.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RL33_PARXL
Sequence: MAKGARDKIKLESTAGTGHFYTTTKNKRNMPEKMLIKKFDPVVRKHVEYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NDUS2_MESAU
Sequence: TYLQALPYFDRLLNIQPPPREKMFEFYERMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRIDEVEEMLTNNRKTQPYDVYDQVEFDVPIGSRLYTEGYQVPPGATYTAIEAPKGHMLADVVAIIGTQDIVFGEIDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity).  Essential for the catalytic activity and assembly of complex I (By similarity).  Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (By similarity).  Plays an important role in carotid body sensing of hypoxia (By similarity).  Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HS71L_MOUSE
Sequence: MAANKGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGHNVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGSHGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCNEVLSWLEANQLAEKDEFDHKRKELENMCNPIITKLYQSGCTGPTCTPGYTPGRAATGPTIEEVD
What is the function of this protein?
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes.  Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.  This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones.  The affinity for polypeptides is regulated by its nucleotide bound state.  In the ATP-bound form, it has a low affinity for substrate proteins.  However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins.  It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.  Positive regulator of PRKN translocation to damaged mitochondria.
What are the official names of this protein?
Heat shock 70 kDa protein 1-like, Heat shock 70 kDa protein 1L, Heat shock 70 kDa-like protein 1, Spermatid-specific heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: REX_CLOBB
Sequence: MDKNKNISMAVIKRLPKYHRYLNELMKNDVDRISSKELGEKIGFTASQIRQDLNCFGDFGQQGYGYNVKELYTQINSILGLDKEYNAVLIGAGNIGQAIANYTRFDKLGIMITAIFDANPKLIGIKIRDIEIRDIDELGSFLKSDSVDIGVICVPKKSAQRVSDELINGGIRGIWNFAPIDLAVPKDVKVENVHLSESVSTLIYQLHQQR
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_BACCQ
Sequence: MNEVLAKGKRAKEVARELVLKSTHQKNEALAAIANQLISETAYILEENKRDIEEGKAKGFSDSLLDRLMLNEQRIVDMTEGIKQLIELRDPVGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVAVIHRALKQTSLPEESVQLIEDTTRDSAKQLFTMNDYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHIFIDETADKQMAFDIIINAKTQRPSVCNAIETIVLHENWAQQYGSELFSSLKERGVELRGDQKALAMDSSIVLASEEDWGTEFLSLTLAVKIVSSIEEAIHHINTYGSMHSEAIISENEENVSKFFVSVDAAALYHNASTRFTDGSEFGFGAEIGISTQKLHVRGPMGLPALTSTKYIIRGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STE23_YEAST
Sequence: MGVSLLASSSAFVTKPLLTQLVHLSPISLNFTVRRFKPFTCLSRYYTTNPYNMTSNFKTFNLDFLKPDLDERSYRFIELPNKLKALLIQDPKADKAAASLDVNIGAFEDPKNLPGLAHFCEHLLFMGSEKFPDENEYSSYLSKHGGSSNAYTASQNTNYFFEVNHQHLFGALDRFSGFFSCPLFNKDSTDKEINAVNSENKKNLQNDIWRIYQLDKSLTNTKHPYHKFSTGNIETLGTLPKENGLNVRDELLKFHKNFYSANLMKLCILGREDLDTLSDWTYDLFKDVANNGREVPLYAEPIMQPEHLQKIIQVRPVKDLKKLEISFTVPDMEEHWESKPPRILSHLIGHEGSGSLLAHLKKLGWANELSAGGHTVSKGNAFFAVDIDLTDNGLTHYRDVIVLIFQYIEMLKNSLPQKWIFNELQDISNATFKFKQAGSPSSTVSSLAKCLEKDYIPVSRILAMGLLTKYEPDLLTQYTDALVPENSRVTLISRSLETDSAEKWYGTAYKVVDYPADLIKNMKSPGLNPALTLPRPNEFVSTNFKVDKIDGIKPLDEPVLLLSDDVSKLWYKKDDRFWQPRGYIYLSFKLPHTHASIINSMLSTLYTQLANDALKDVQYDAACADLRISFNKTNQGLAITASGFNEKLIILLTRFLQGVNSFEPKKDRFEILKDKTIRHLKNLLYEVPYSQMSNYYNAIINERSWSTAEKLQVFEKLTFEQLINFIPTIYEGVYFETLIHGNIKHEEALEVDSLIKSLIPNNIHNLQVSNNRLRSYLLPKGKTFRYETALKDSQNVNSCIQHVTQLDVYSEDLSALSGLFAQLIHEPCFDTLRTKEQLGYVVFSSSLNNHGTANIRILIQSEHTTPYLEWRINNFYETFGQVLRDMPEEDFEKHKEALCNSLLQKFKNMAEESARYTAAIYLGDYNFTHRQKKAKLVANITKQQMIDFYENYIMSENASKLILHLKSQVENKELNENELDTAKYPTGQLIEDVGAFKSTLFVAPVRQPMKDFEISAPPKLNNSSESE
What is the function of this protein?
Involved in the N-terminal endoproteolytic cleavage of the P2 precursor of the a-factor mating pheromone.  Capable of proteolysing the established mammalian insulin-degrading enzymes (IDEs) substrates amyloid-beta peptide and insulin B-chain.
What are the official names of this protein?
A-factor-processing enzyme, Insulin-degrading enzyme homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: PGK_ACIBY
Sequence: MNFQRMTDLNLAGKRVLIREDLNVPVKNGVITSDARLRAALPTIKAALEKGAAVMVFSHLGRPVEGEPKPEQSLAPVAAYLTEALGQEVKLFTDYLDGVEVEAGQVVLLENVRFNPGEKKNNPELAQKYAALCDVFVMDAFGTAHRAEASTEGVARFAPVAAAGPLLAAELDALGRAMQTPEKPMVAIVAGSKVSTKLDVLNSLSGICDQLIVGGGIANTFLAAAGYNVGKSLYEADLVETAKQIAAKVSVPLPTDVVVADASQINFEDFLGSLAAAQAVIKKVEDVTANDMILDVGPETAKAFANILTTSKTILWNGPVGVFEVDQFGEGTKALSLAVAQSDAFSIAGGGDTLAAIDKYNVADQIGYISTGGGAFLEFVEGKTLPAVAVLLERA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_PSEA8
Sequence: MNTLLMHCRPGFEGEVCAEIAEHAATLEIPGYAKSKPASAHVEFVCQDADGAERLMRRLRFADLIFPRQWARGPGFIELPESQRIEVLLAELASYPVCGSLWLEVLDTNAGKEVSTFCRKFEKPLRAALVKAGRLQEDPALPRLLLTFRSGREVFVGLAEPRNSALWPMGIPRLKFPREAPSRSTLKLEEAWHQFIPRSEWDKRLAPDMLAVDLGAAPGGWTWQLVNREMRVTAVDNGPMAENLMYSGLVDHQKVDGYQYRPRQRVDWMVCDIVEKPARTGALIETWIGEGLCREAVVNLKLPMKQRYAEVRKILQRLRESFDARGLKVAIGCKQLYHDREEVTCHLRRLER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_GEODF
Sequence: MSFIDEVKIHVKSGDGGPGCVSFRHEKFIEFGGPDGGDGGKGGNVIVEASRNLSTLLDLRQHPHQKAGSGKNGMGKDRHGAYGKDLRLLLPVGTVIKDAETDEVLADLTEPGQPLVLLKGGRGGQGNARFATATHKAPRFAQPGEPGEERWLRLELKLMADVGLLGMPSVGKSSLITKVSAARPKIAEYHFTTLKPNLGVVAYKNYKSFVMADIPGLIEGAHEGAGLGHRFLKHLERTGHLLHILDISWMPDRDPIREYEAINKELSLFNPELAEKKQTIVINKMDLPVVKENLAKVLPYFQERGLKVFPISAATGEGIPALLDEIARQLWGAAEEEW
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_MARN8
Sequence: MRRRIVAGNWKMNGSKDLVKQLVGAVREQSGSVGEDVEVVIIPPAIYLDQVAEQGGGRITTGAQNVSQWQSGAYTGEISAEMARDMGCGYVLVGHSERRQLFGETDSVAAAKVEQVLLSGLVAVLCVGETLAEREADQAEAVVAEQVRSGLSVVADGQWSRVVVAYEPVWAIGTGKTATADDAQAMHSEIRKVLDGMNAPANEISVLYGGSVKADNAAALFAEPDIDGGLIGGASLKAEEFISICRSFPAGV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPP1_MOUSE
Sequence: MGLQARLLGLLALVIAGKCTYNPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQRNLERLSELVQAVSDPSSPQYGKYLTLEDVAELVQPSPLTLLTVQKWLSAAGARNCDSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPTKTHVIRSPHPYQLPQALAPHVDFVGGLHRFPPSSPRQRPEPQQVGTVSLHLGVTPSVLRQRYNLTAKDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGGSFTHQASVAKVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSIYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSGRHKFRPSFPASSPYVTTVGGTSFKNPFLITDEVVDYISGGGFSNVFPRPPYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRILNGRPPLGFLNPRLYQQHGTGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
What is the function of this protein?
Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:28464005).  May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (By similarity).  Requires substrates with an unsubstituted N-terminus (By similarity).
What are the official names of this protein?
Tripeptidyl-peptidase 1, TPP-1, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I.
What are the subcellular locations of this protein?
Lysosome. Melanosome.
Protein: PSBQ2_MAIZE
Sequence: MAQAMASMTGLSQGVCPAAADSRTRTAVVVVRASAEGDRCAGGPRCDRLVATASSPPLSQAVHAETVKTIKIGAPPPPSGGLPGTLNSDQTRDFDLPLKERFYLQPLPPAEAVARVKTSAQDIINLKPLIDKKAWPYVQNDLRLRASYLRYDLKTVIASKPKEEKKSLKELTGKLFSTIDDLDHAAKMKSTPEAEKYFAATKDALGDVLAKLG
What are the official names of this protein?
Oxygen-evolving enhancer protein 3-2, chloroplastic, OEE3, 16 kDa subunit of oxygen evolving system of photosystem II, Ferredoxin-NADP reductase-binding protein, BP, OEC 16 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: ARGB_SHEPA
Sequence: MTQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQLKANGMITEKLDGLRVTPEAQIPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMNAKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAISEQGEMLNVNADQAATALAKLVSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQAVQIASWRHAHQLIALCQGEAVGTQIQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPR2_ARATH
Sequence: MEMVNAEAKQSVPLLTPYKMGRFNLSHRVVLAPLTRQKSYGSVPQPHAILYYSQRTSPGGFLIAEATGVSDTAQGYPDTPGIWTKEHVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNRGFQPRRQAPISCTGKPIMPQMRANGIDEARFTPPRRLSIEEIPGIVNDFRLAARNAMEAGFDGVEIHGAHGYLIDQFMKDKVNDRTDEYGGSLQNRCKFALEVVDAVAKEIGPDRVGIRLSPFADYMESGDTNPEALGLYMVESLNKYGILYCHMIEPRMKTVGEIAACSHTLMPMREAFKGTFISAGGFTREDGNEAVAKGRTDLVAYGRWFLANPDLPKRFQLDAPLNKYNRSTFYTSDPVVGYTDYPSLESTA
What is the function of this protein?
Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds (Probable).  May be involved in the biosynthesis or metabolism of oxylipin signaling molecules (PubMed:10872231) (Probable).  In vitro, reduces 9R,13R-12-oxophytodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but only poorly 9S,13S-OPDA, the natural precursor of jasmonic acid (JA) (PubMed:10872231).  Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT) (PubMed:19605548).  Functions in an alternative and OPR3-independent pathway for JA biosynthesis (PubMed:29291349).  Catalyzes the NADPH-dependent reduction of 4,5-didehydrojasmonates to jasmonates (PubMed:29291349).
What are the official names of this protein?
12-oxophytodienoate reductase 2, 12-oxophytodienoate-10,11-reductase 2, AtOPR2, OPDA-reductase 2, 4,5-didehydrojasmonate reductase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4618_BURO0
Sequence: MNTTPDTPTPRALRELTPLEARILGVLVEKQHTVPDTYPLSLNALTAGCNQKTARSPVMNVSEDEVTTALDELKRLSLVMEGSSSRVPRFEHNMNRVLGIPSQAIALLTILLLRGPQTAAELRLNSARLHGFADISSVEAFLDELAARAQPLVVRLPRAPGARENRWMHLMCGEVNMADFASADAGGGADSVPPSEFEALKAEQKRLADEVARLNALVQRMASELGIDVDAPGDAS
What are the official names of this protein?
UPF0502 protein Bcenmc03_4618.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: UBIC_CUPPJ
Sequence: MSAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFLDEWQVLGQCGREPALTREVLLICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLFVDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPARRSVFRRGAGVMLVTEVFLPDLLTRPSRGLGQRY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.