PharMolix/UniProtQA huggingface dataset:
Protein: SAV_DROME
Sequence: MNYLTILLCNRKPTMLSRRNKEKSQHKEGVVGKYMKKDTPPDISVINVWSDQRAKKKSLQRCASTSPSCEFHPRSSSTSRNTYSCTDSQPDYYHARRAQSQMPLQQHSHSHPHSLPHPSHPHVRSHPPLPPHQFRASSNQLSQNSSNYVNFEQIERMRRQQSSPLLQTTSSPAPGAGGFQRSYSTTQRQHHPHLGGDSYDADQGLLSASYANMLQLPQRPHSPAHYAVPPQQQQHPQIHQQHASTPFGSTLRFDRAAMSIRERQPRYQPTSSPMQQQQQQQQQQQQQLQHTQLAAHLGGSYSSDSYPIYENPSRVISMRATQSQRSESPIYSNTTASSATLAVVPQHHHQGHLAVPSGSGGGSLSGSGRGGSSGSVRGASTSVQSLYVPPRTPPSAVAGAGGSANGSLQKVPSQQSLTEPEELPLPPGWATQYTLHGRKYYIDHNAHTTHWNHPLEREGLPVGWRRVVSKMHGTYYENQYTGQSQRQHPCLTSYYVYTTSAEPPKAIRPEASLYAPPTHTHNALVPANPYLLEEIPKWLAVYSEADSSKDHLLQFNMFSLPELEGFDSMLVRLFKQELGTIVGFYERYRRALILEKNRRAGQNQNQNQ
What is the function of this protein?
Plays a key role in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein.  The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam.  Required for cell cycle exit in eye imaginal disk and hid-induced apoptotic cell deaths that are part of normal retinal development.  Activation of Drice in eye imaginal disk by either Hid or Rpr is almost completely blocked by Sav expression.
What are the official names of this protein?
Scaffold protein salvador, Shar-pei.
Protein: UBP9_YEAST
Sequence: MIKRWLSVNRKKSHPEKNTQGNDEINRKATSLKKTKGSGDPSIAKSPSAKSSTSSIPSNLASHERRSKFSSQTDNLAGNKHYHEHYHNMASTSDEREYDSSTTYEDRAFDTESSILFTTITDLMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPERVAAVNRIRKSDLKGSKIRVFTNESFETSTNSGNSNTGYQSNDNEDAHNHHHLQQSDQDNSSSSTQEKQNNFERKRNSFMGFGKDKSNYKDSAKKDDNNEMERPQPVHTVVMASDTLTEKLHEGCKKIIVGRPLLKQSDSLSKASTTDCQANSHCQCDSQGSRITSVDDDVLVNPESCNDAVNNSNNNKENTFPTSEQRKKAALIRGPVLNVDHLLYPTEEATLYNGLKDIFESITENLSLTGIVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDNFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYKKYELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFYKETQADKTENQNENIDTSSQDQMQTDNNIEQLIKCDDWLRDRKLRAAANIERKKTLGNIPEVKTAETKTPLNDKKRNKQKRKSRILSFIK
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 9, Deubiquitinating enzyme 9, Ubiquitin thioesterase 9, Ubiquitin-specific-processing protease 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RRP9_YEAST
Sequence: MSDVTQQKKRKRSKGEVNPSKPTVDEEITDPSSNEDEQLEVSDEEDALESEEEFEGENPADKRRRLAKQYLENLKSEANDILTDNRNAEEKDLNNLKERTIDEYNNFDAGDLDKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQTGF
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for efficient pre-rRNA cleavage at sites A0, A1 and A2, and biosynthesis of 18S rRNA.
What are the official names of this protein?
Ribosomal RNA-processing protein 9.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RRP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HEM3_KLULA
Sequence: MESKETVRIGGRRSKLAVVQSEQVKVMIESKFSHIECPLLSVHTLGDQVQSKPLYSFGGKAVWTKELEDLLYKDDESRIDLIVHSLKDMPTLLPDGFELGGITKRVDPTDALVMPIGSPYSSLSELPDGSVVGTSSVRRSAQLKRKFPNLKFESIRGNIQTRLAKLDDPETPYKCIVLASAGLMRSGLDSRITQRFNADTMCYAVGQGALGIEIRKDDEKMKKILKEICDPSTTICCLAERSLLRTLEGGCSVPIGVVSNYDESTKVLTLKGIVINVEGTEWVEIEHKVTISNEREDSINCGKELAAKLTQNGAKEILDSINLDKIT
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PHS_KORVE
Sequence: MSKTLTDPELQTALGSLHGWAKNGIAIERKYEFKDFLEAMKFVNKVADAAEAAGHHPDIQIVYSRVTLQLTSHDSGGVTHRDIKMAGRLNEIHP
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MURG_PARPJ
Sequence: MTALPQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWKVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGMKTKLMLPVNLLRACTQSLSVLRRVKPDVVLGMGGYITFPAGLMTALSGRPLVLHEQNSIAGLANKVLAKVAKRVLVAFPNALPHGEWTGNPIREELARAIAPKARYAQRSGPLNVLVVGGSLGAAALNEVVPRAVALLAPNERPRIVHQAGAKHIEALRENYSAAGLQAGADVELVPFIDDMTSAYANADLVICRSGAMTVSEISAVGVAAFFVPFPYAVDDHQTTNAAFLADNGAALVVQQRDLSAETLADWLRSQTRETLAEMAERSRSLAKPDATEQVAQICATVAGSISGASPEGKQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPL_SALG2
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_CHLPD
Sequence: MHDSDRQKTILAILGPTASGKSALAFSIAKEINAEIISADSRQIYRELNIGTAKPSQETLRQIKHHFVNELSIGDPFTAGNFAREASARIRNILHSGKNVLIAGGSTLYLEALLNGFADLPPADTEKRQQLAIELETFGSKHLFERLRQLDPLQAATLDHTKTQRLVRSLEIIELSGHTVTEMQKKHIQPLADINVITCGLSLPRPLLYEKINRRTDQMLASGLLQEAVALFTKYYPYCDVITTNALQTVGYQELFAYLDEKTDFKTAITLIKQHTRNYAKRQLTFFKNRLNVNWMDAPENEHELSMLTTSCCRMITGN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: KUP2_RHOP5
Sequence: MALSSVEPTEAPRATGFGALTLGSIGVVFGDIGTSPLYAFREAVHVAAEGAPVTRVIVLGVLSLILWSLLIVVTAKYVLLLLRADNNGEGGTLSLMALGQRALGRRSVPLLVLGVIGASMFIGDSMITPAISVLSAVEGLKIAAPALQHYVVPLTVGILVALFAFQRWGTAKVASAFGPVMVLWFSTLAVLGLLHINDDPSVIAAINPWYAVEFMLSHGVIALVTIGAVFLAVTGGEALYADLGHFGRKPIQAGWLFFVLPSLLLNYFGQGAMVLAHPDAVENTFYRMVPENLLVPMILLATAATVIASQAVITGAFSLISQAVQLGLLPRFEVRYTSETHAGQIYLPRVNMLLLAGVLLLVLLFHSSSALAAAYGIAVSTTMVVDGVMGFVVVWKLWGWRPAAAAALIIPFVAVDAIFFSANLLKLMEGAWVPLLFGFLMAMLVWTWRRGSAMLILKTRRTEVPLPDLIRSLEKRPPHIVRGTAVFLTSDPEYVPSALLHNLKHNKVLHEHNVILTIETAQTPRVDLADRVRMESLGDKFARVRLRFGFMESPNVPKALVIARKLGWQFDIMSTSFFVSRRSLKPAAQSGMPRWQNGLFIALSRSANDATDYFQIPTGRVVEVGTQVTI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YABA_STRP6
Sequence: MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: LRP10_HUMAN
Sequence: MLLATLLLLLLGGALAHPDRIIFPNHACEDPPAVLLEVQGTLQRPLVRDSRTSPANCTWLILGSKEQTVTIRFQKLHLACGSERLTLRSPLQPLISLCEAPPSPLQLPGGNVTITYSYAGARAPMGQGFLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDPFPGLTPRPVPSLPCNVTLEDFYGVFSSPGYTHLASVSHPQSCHWLLDPHDGRRLAVRFTALDLGFGDAVHVYDGPGPPESSRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGAGEGLGERCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCSYVLPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGGPGARRRQRGRLMRRLVRRLRRWGLLPRTNTPARASEARSQVTPSAAPLEALDGGTGPAREGGAVGGQDGEQAPPLPIKAPLPSASTSPAPTTVPEAPGPLPSLPLEPSLLSGVVQALRGRLLPSLGPPGPTRSPPGPHTAVLALEDEDDVLLVPLAEPGVWVAEAEDEPLLT
What is the function of this protein?
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction.  May be involved in the uptake of lipoprotein APOE in liver (By similarity).
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 10, LRP-10.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Membrane, coated pit.
Protein: SYP_XYLFM
Sequence: MRLSEFHLHTTKEIPADAELVSHRLMLRAGMIRKLASGLYTWSPLGLRVLRKVEAIVRDEMNRAGAVEMLLPTIQPRELWEESERWEKFGSQLLKIKDRKQAEYCYSPTAEEAVTDYVRQELTSYKQLPVNLYQIQTKFRDEIRPRFGVMRAREFVMKDAYSFHLSDADLVREYENMRATYTRIFTRLGLEFRSVQADSGAIGGDASQEFHVIADSGEDVLAFSTGSDYAANIEAAIAATPGPRLTAKETLQKVSTPTQKRCEDVTALLDIPLQRMVKSIAVMTDSGFFLALLRGDHTLNDIKLSRLPGLANFRLANEVEIARHLGSEPGFLGPVCPGMSIRIIADCEVAVMADFVVGANEVGFHLVGVNWGRDLPEPEVVADIRNVIEGDRAVDGGKICIARGIEVGHVFQLGRKYAEAMKATVLDEYGKAVTMTMGCYGIGVSRIVAAAIEQNHDVAGIIWPAPIAPWQVAVCVINPKKDPVIIAAAELLLAELQSADVDTVLDDRGLRPGVMFADMELIGIPHRIVVSERGLAAGTYEYRARRTAMVENLDKTTLLTRIKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA21_ARATH
Sequence: MHRASSKHTNAKKEAISTSKIRDNNVRVTRSRAKALGVSNSPSKPAFKHETKRVARPSNKRMASDNITVCNQKRRAVLKDVTNTLAESIISTEGNVKACKRGGKETKQIEEDGLVDVDGEKSKLAEDLSKIRMVESLDASASKQKLVDCAEEDRSDVTDCVQIVDIDSGVQDPQFCSLYAASIYDSINVAELEQRPSTSYMVQVQRDIDPTMRGILIDWLVEVSEEYKLVSDTLYLTVNLIDRFMSHNYIEKQKLQLLGITCMLIASKYEEISAPRLEEFCFITDNTYTRLEVLSMEIKVLNSLHFRLSVPTTKTFLRRFIRAAQASDKVPLIEMEYLANYFAELTLTEYTFLRFLPSLIAASAVFLARWTLDQSNHPWNQTLQHYTRYETSALKNTVLAMEELQLNTSGSTLIAIHTKYNQQKFKRVATLTSPERVNTLFSR
What is the function of this protein?
May negatively regulate endocycles and act as a regulator of ploidy levels in endoreduplication.
What are the official names of this protein?
Cyclin-A2-1, Cyc3a-At, Cyclin-3a, G2/mitotic-specific cyclin-A2-1, CycA2;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RS8_STREM
Sequence: MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREGFIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLGIAIISTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y2431_BACP2
Sequence: MKEETFYLVREDVLPDAMRKTLEVKKLLDRKKADSVADAVQQADLSRSAFYKYRDAVFPFYTMVKEQIITLFFHLEDRSGALSRLLQIVADSGCNVLSIHQTIPLQGRANVTLSISTAGMADDINTVMNQLRKLEFVEKVEILGSGA
What are the official names of this protein?
UPF0735 ACT domain-containing protein BPUM_2431.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: MDH_YERPP
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSDLSLYDIAPVTPGVAVDLSHIPTAVNIKGFSGEDATPALQGADIVLISAGVARKPGMDRSDLFNVNAGIVRNLVEQIARTCPNALIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGITTLDTIRSNTFVAELKGKQPQDIEVPVIGGHSGVTILPLLSQIPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGESNVVECSYVEGDGKYARFFAQPILLGKNGVAERKDIGKLSAFEQQALENMLDVLHKDIELGEKFVNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: CDR_STAA9
Sequence: MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALVYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVIGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKLIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
What is the function of this protein?
Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
What are the official names of this protein?
Coenzyme A disulfide reductase, CoA-disulfide reductase, CoADR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
Protein: SMG8_DROSE
Sequence: MLDDYYTWTYPDIPENVAQELLQLNGSLVVVGVVGRSDCDLANKMLAFGMEPPDDHTPEDGQIQCYYKPGTFSLLLHFESTYDAEISGQMIDVCIEDVDTPFDIDSFFERIRCRFVRMMLLALHVCHIVVWAKFAREQHLMQFLPQMLRETPAARISERTRLCAPRILFLFENFPGDEPKTRESVSTCEFQMEDCIYELLRRYNIVTNSSSNSLVALPNNKQFVFFNAHEELRDDKLLKAIDCLNETMYKPDLKEEEEDLEILAMAPFDGFVKPFTMPVYEKEWENLQYQEDHTVWNFLQRHVHDALVGCFDAGSFKQHAQQGPFQLLNSREWHDCMATMHKLLVENAKDPDHETSNEEYKLFLKNFDEDLNYEKKFWAHLCELGLKKGIAAYKNAAPANYGTATHRQLLADATLAFEEEGRGPQAQAALAKLAAICHKHWEDGRQQCEQLSLRSHPCTLPKNMPHEKHNSGVIHISTCNCGRTQGRREDPFNLRQANYEFYEHIAQMCNLCVKVKQYQFPIFEPSVSDYRAAAFEAAFPLLNTGKSGAPQDEDAGEDEAEEEEGQERELPTKKQLQNTASNCCSHPLSPTFGSDLNMSIAGFGASLKESQARSEQLSNSEQNTTRSGSSSVDTENELVVELQEPAKKEAREDVGPTDAVSTSTTEYLPGLVHTVSNFDLLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVQLRLVHALKQQYQHHHHGKKQQRWKKQGDRLSLKIFVGMEYECSRGHRFMMCAPDRVLRGGADIERDTCSKVVHNNMPLYYPCPCRSQKNFLAQLMRIHVVTPKAPVNIIVDPKVCVGRYTFTLGSILPPRLSQSAYWIIRLPYVYQGDDVLIAPPDQLDPDYPLAGGYLLPGMFGVVETDPTLDLNEPGMMGASAAGNFTRI
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: RLMN_STRP2
Sequence: MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVDCNIGCTFCASDLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVMGIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALELAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEYGTDIDAACGQLRSNTMKRDRQKAVAEVNP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y07E_BPT4
Sequence: MEGSSIDVTFTAQLETGETLVSINITSYEETPGVLVEENRLYGTYESVFGFGNDALKYRLGDEFKTAASWEELPTDSDTQLYLWKAPQNLQKTFTYEVTLIYDYQEQSESGGSGSNSRSSSDTTEPTDPPAPVRKTLVKNYTKTIVGNWSRWANKLRKYAYARP
What are the official names of this protein?
Uncharacterized 18.5 kDa protein in repEA-segC intergenic region.
Protein: PTH_SALRD
Sequence: MSTPSLLAIGLGNPGAEYEDTRHNVGHQVIDGLSGRLDISLQHQSDALVGWGRYVDQKIGLAVPLTYMNRSGDAVAGLRAHYDLPIDRLLVIVDDLHLPVGTIRLRPTGSSGGHNGLAHVAQRLGTTEFSRLRVGIGNDFPEGRQSDYVLSPFTDEQRPAARSAREDAEDAVLTMARDDIDAAMNRFN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_SHELP
Sequence: MQNAPESVLNALVPMVVEQTAKGERSYDIYSRLLKERVIFLVGQVEEHMANLIVAQLLFLESESPDKDIYLYINSPGGSVTAGMAIYDTMQFIKPNVSTVCIGQAASMGAFLLAGGAKGKRHCLPNSRVMIHQPLGGFQGQASDIAIHAQEILGIKNKLNQMLADHTGQPLEVIERDTDRDNFMSATEAAEYGLVDSVLDKRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWZF3_ORYSJ
Sequence: MPSNGGIIPGPANAASLPAPVLIEDNWVCCDMCHKWRLLPYGTNTSMLPKKWICSMLDWLPGMNKCDISEDETTNALNALYVTQIPAAGVSSGGPHTAHASVAASSTYNISGQLGQSRKRKNALKDENCYEHDQQAPAKMTLTSNQQAPAKNREVVDSEHYTNDRDPVSTHDLVPQSKSASERHKSKHKSRSSHSDGGDLTEKSKKHSKSKNRRGIDRDEHKTSKKTKKEDRHYFNKDWKNEYDLAGNKVRDETKALSAKAKMSKDSCEQDEFSLRKEKASRFDILEKTKRINDDDVAFHEKMKEHRAGIETLDLSGKKKTVKEWEDNRLSSMDHTSKGGDNENLNERLSKIKKSEARPEEVQDANALFSSAGRRQDNELVADNKFVTCKEGPSELWDNQPPRQVLNLAEPTRRDVACLQSSTVATSSSSKVSSSRRNKNSREAKGSPVESVSSSPLKNSNTDKISKARKTGKDGELNADSSILHTPMKYPTHEVGLLHTGQQAVGEAILRGSTNNSGMGRVDNQLYPGDKKILDMHGPTLQPDQQDCFNPRATADSTGHKSKNSAPSRQGRNGSSNLISEGNKQIEMSSRKEKLRPSIDNQDMQKSIGQDNHSHMKEGKSEVHTTRVKPGASKNHTQLRSNVENGDSASPIRRDGNMIAFALKEARDLKHKANHLKEKGLELESMGLYFEAALKFLHVASLWETPNLDNSRSGDVAQSMKMYSETAKLCSFCAHAYERCNKMASAALAYKCVEVAYLKAAYYKHPSASKDRQELQSVVQIAPGESPSSSASDIDNLNSHGLSKALSTKGGNSPQVAGNHLPLAVRNQAHLLRLLAYTNDVNCAFDATRKSQVAIASAASSQERGKTVDDGLASVRTVLDFNFNNVNELLRLVRLSMELINT
What is the function of this protein?
Binds to histones H3K4me1, H3K4me2 and H3K4me3 in GST pull-down assay (PubMed:28818372).  May facilitate the recruitment of effectors to mediate gene expression (By similarity).
What are the official names of this protein?
Cysteine-tryptophan domain-containing zinc finger protein 3, OsCW-ZF3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_CLOPS
Sequence: MQYFDLMKKACDSVGMEFNEDKYQKFMLYKDLLKEWNEKINLTAITEDEEIVKKHFIDCIKAFKADEFKKAKTVIDVGTGAGFPGLPIAIMREDVEVTLLDSLNKRINFLNEVVNKLALKNVETIHSRAEDGARKKELRENFDIATSRAVANMCVLSEFCIPYVKVNGNFIALKGPNITEELNDSKNAIGTLGGKLKGITEVEIEGTDLNHNLVIVDKIKSTPKTFPRKAGNVTKKPLK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MICFO
Sequence: MTVIRKTHPLIKMINHSFXDLPAPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMTETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDTDKIPFHPYYTIKDFLGILILLMVFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPILHTSKQRALTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFTIIMILMPIAGMIENNILDLE
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: F16PA_SHIDS
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.