PharMolix/UniProtQA huggingface dataset:
Protein: RF1_BUCA5
Sequence: MNNSILNKLKSLRNRYQEIEIMLTQKNVISNRENLKTLSKEYLKLSEIIKYFIEWEKLEVDIENVNILLNDVEIQGMAEEELYFFNKKKKALEKKINQLLLPEDPNDKHSCFIEIRSATGGDESSIFAGELFRMYLRYAESYSWKVEIMNTSESEKGGFKEIIAKITGRGACGRLKFESGGHRVQRVPETESQGRIHTSTCTVAVMPVTPKTEKEEINSSDLKIDTFRSSGAGGQHVNTTDSAIRITHIPTGNVVECQDERSQHKNKAKALSILSARVYAAKLEKDRQESSSMRKILLGTGERSDRNRTYNFPQNRITDHRINLSIYKLDEVLQGKLDLLIDPIIQEYQADMLSSLSKSES
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB1_HALSA
Sequence: MTENTAETADESSDGGVTATTGAATTTPTTPPEPVIRARDLDVFYGSERALESVDIDIPEQQVTAIIGPSGCGKSTFLRCINRMNDRIDAARIDGDLTLRGTNVYDAAVDPVALRRRVGMVFQEPNPFPKSIYDNVAYGLEIQDVEGDHDEIVEQSLRRAALWDEVSHQLDSSGVALSGGQQQRLCIARAIAPDPEVLLMDEPASALDPVATSQVEDLIEELAEEYTVVIVTHNMQQAARISDKTAVFLTGGKLVEFGDTDQIFENPEHQRVEEYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MGST3_MOUSE
Sequence: MAVLSKEYGFVLLTGAASFVMVLHLAINVGKARKKYKVEYPVMYSTDPENGHMFNCIQRAHQNTLEVYPPFLFFLTVGGVYHPRIASGLGLAWIIGRVLYAYGYYTGDPSKRYRGAVGSLALFALMGTTVCSAFQHLGWIRPGLGYGSRSCHH
What is the function of this protein?
Catalyzes oxydation of hydroxy-fatty acids.  May participate to the lipid metabolism.
What are the official names of this protein?
Microsomal glutathione S-transferase 3, Microsomal GST-3, Glutathione peroxidase MGST3, Microsomal glutathione S-transferase III, Microsomal GST-III.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Microsome membrane; Lipid-anchor. Membrane.
Protein: ILVC_RUEST
Sequence: MRVYYDRDCDVNLIKEKKVAILGYGSQGHAHALNLRDSGAKNLVIALREGSPSAKKAEAEGLQVMGIAEAAAWCDVIMFTMPDELQAETYKKYVHDNIKPGAAIAFAHGLNVHFGLIEPKEGVDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVHNDASGSALETALSYCSAIGGGRSGIIETNFREECETDLFGEQAVLCGGLVELIRCGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMDYSISNTAEYGQYVTGPRILKYDETKARMKEVLADIQQGKFVRDFMLENAVGQPTIKASRRANDEHAIEATGAKLREMMPWISAGKMVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LEU3_BRUME
Sequence: MASRKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQAISDADMEKALAADAVLFGAVGGPKWDSVPYEVRPEGGLLRLRKDMQLYANLRPAICYPALAHSSSLKPEVIEGLDILILRELTGGVYFGEPKEIIDLGNGQKRGIDTQVYDTYEIERIADVAFELARTRRNKVTSMEKRNVMKSGVLWNQGVTARHKEKHADVQLEHMLADAGGMQLVRWPKQFDVILTDNLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPVHGSAPDIAGKGIANPIAMIASLAMCLRYSFGLVAEADRLEAAIAGVLDDGIRTADIWSEGNTKVGTTEMGDAILAKFKALSA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_PSEA7
Sequence: MAKKLFIETHGCQMNEYDSSRMADLLGEHQALEVTENAAEADVILLNTCSIREKAQEKVFSKLGMWRDLKQQNPDLVIGVGGCVASQEGAAIRERAPYVDVVFGPQTLHRLPEMIDAARSTRKPQVDVSFPEIEKFDRLPEPRVDGPTAFVSVMEGCSKYCSFCVVPYTRGEEVSRPFDDVIAEVIHLAENGVREVTLLGQNVNGFRGQTHDGRLADFAELLRVVAAVDGIERIRYTTSHPLEFSDALIQAHAEVPELVKFIHLPVQSGSDRVLAAMKRNHTVLEYKSRIRKLKAAVPDICISSDFIVGFPGETEKDFEQTMKLVEEVGFDFSFSFIYSARPGTPAADLADDLPEEVKKRRLQILQGRIHQQGYEISRRMVGSTQRILVTDFSKKDPGMLQGRTENNRIVNFRCDNPRLIGQFAQVHIDDALPHSLRGTLIEGTLH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBR7_HUMAN
Sequence: MAGAEGAAGRQSELEPVVSLVDVLEEDEELENEACAVLGGSDSEKCSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKFKNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPYPDPEDEIPDEMIQCVVCEDWFHGRHLGAIPPESGDFQEMVCQACMKRCSFLWAYAAQLAVTKISTEDDGLVRNIDGIGDQEVIKPENGEHQDSTLKEDVPEQGKDDVREVKVEQNSEPCAGSSSESDLQTVFKNESLNAESKSGCKLQELKAKQLIKKDTATYWPLNWRSKLCTCQDCMKMYGDLDVLFLTDEYDTVLAYENKGKIAQATDRSDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGMQYYCS
What is the function of this protein?
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway.  Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase UBR7, N-recognin-7, RING-type E3 ubiquitin transferase UBR7.
Protein: NUOI_RICRS
Sequence: MINYLKSFFLYEIVRGMALTLKYFFKPKVTINYPYEKSPISPRFKGEHALRRYEHGEERCIACKLCEAICPAQAIVIEADEREDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFASLTHTALIYDKERLLQNGDRWEQALASKLHKDYEYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1751_LISMO
Sequence: MEASLLKKNQSIELTIEDLTHDGSGVGKIDGYPFFIPNTLPGEKVTAKIIKLNKNYGFARMENIETVSANRVEPPCAVYSKCGGCSLQHLSYDGQLEFKRNQVEETMKRIGKLNVEVPETLGMENPWRYRNKSQVPVGFVNGKLTAGFYQKRSHAIIDMSTCLIHNEQGDFAVQKTREILAKYGTEPYDEQTGKGDIRHIMTRFAHTTGQLMIVLVTTKERMPFKEEIVRDLVEQLELTSIVQNINPHKTNVIFGDRTKTLWGKDIIEDTIHGIRFAISARSFYQVNPLQTEVLYQQAIDAAELTGEETVIDAYCGIGSISLCLAKKAKHVYGVEIVDQAIQDARANAELNELANTTFETGKAEEVIPSWYKAGIVADVLVVDPPRKGCDEKLLETILAMKPKKVVYVSCNPGTLARDMKILTDGGYVAKKVQPVDMFPMTTHIEAVTVLHLN
What are the official names of this protein?
Uncharacterized RNA methyltransferase lmo1751.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: HSP02_PSEMZ
Sequence: ELLSEINR
What is the function of this protein?
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
What are the official names of this protein?
Putative heat shock protein 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL1_ARATH
Sequence: MALTWTHKDRGEIRVHENLEELSIDLVDYIAEISEASIKEHGAFCIVLSGGSLISFMGKLIEPPYDKIVDWAKWYVFWADERVVAKNHDDSNYKLAKDNLLSKVNVFPRHICSINDTVSAEEAATEYEFAIRQMVRSRTVAASDNSDSPRFDLILLGMGSDGHVASLFPNHPALEVKDDWVTFLTDSHKPPPERITFTLPVINSAANVVVVATGESKANAIHLAIDDLPLPDSSLSLPARLVHPSNGNLIWFMDKQAGSKLDRFKFSE
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
Probable 6-phosphogluconolactonase 1, 6PGL1.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: UBR3_HUMAN
Sequence: MAAAAAAAVGGQQPSQPELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLSAERPLAAAAGGEDAAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTSGLGENACVKKSHEKYLIALKSSGLTYPEDKLVYGVQEPSAGTSSLAVQGFIGATGTLGQVDSSDEDDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDEPAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSVLPDQEMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNTVLDAEHERSMLEGALTFLVILLSLRLHLGMSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPVFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFPGNPWPPYKKRTSLHPSYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSAEEESDEEASVGGPERCHDSWFPGSNLVSNMRHFINYVRVRVPETAPEVKRDSPASTSSDNLGSLQNSGTAQVFSLVAERRKKFQEIINRSSSEANQVVRPKTSSKWSAPGSAPQLTTAILEIKESILSLLIKLHHKLSGKQNSYYPPWLDDIEILIQPEIPKYSHGDGITAVERILLKAASQSRMNKRIIEEICRKVTPPVPPKKVTAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTAEPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPISEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNPWQRPSNKSIQDLIKEVEELQGRPGAFPSETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGNLCSGGASTAGKRSCLNQLFHVLALHMRLYSIDSEYNPWRKLTQLEEMNPQLGYEEQQPEVPILYHDVTSLLLIQILMMPQPLRKDHFTCIVKVLFTLLYTQALAALSVKCSEEDRSAWKHAGALKKSTCDAEKSYEVLLSFVISELFKGKLYHEEGTQECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLPSCQEEEEFSVLASCLGLLPTFYQTEHPFISASCLDWPVPAFDIITQWCFEIKSFTERHAEQGKALLIQESKWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYKVLEQQWISHTFDHINKRWGPHYNGL
What is the function of this protein?
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity).  Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).  May play a role in Shh signaling by mediating the ubiquitination of Kif7 (By similarity).  May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A (PubMed:27331610).
What are the official names of this protein?
E3 ubiquitin-protein ligase UBR3, N-recognin-3, RING-type E3 ubiquitin transferase UBR3, Ubiquitin-protein ligase E3-alpha-3, Ubiquitin-protein ligase E3-alpha-III, Zinc finger protein 650.
What is the protein family that this protein belongs to?
Belongs to the UBR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUR7_PSESM
Sequence: MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGTVNNKFNAFIMQKLEEAGIPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGIEEGTKLNPYTFELFLKDDAKGDPFINESHVVAFGWGTAEQLVRMKELSIKVNEVLTKLFDDAGLLLVDFKLEFGVFHGEIVLGDEFSPDGCRLWDKDTRKKMDKDRFRQGLGDVIEAYEEVANRLGVPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y122_OSHVF
Sequence: MDALMVFDDMLDIPMSMQNNMIADDLLEQAAATASIAPIDIPMTPLQPEMEEEPEVEPEPVSQPEVVQVIEEPPTSTLVANERSEDFFEAAALLETVMEYVNSNDFTLKQLLAFNAAKKPKKSRKRKADSDAAPKQKKEKVEERYCVDSYEITEEIKGEIASAYEGLGALTPLRCAELIKESHELNGKIGGLDTIKDYVTLFSGRVCLYNTPANDVLTSYRKTYTNRYLERNKPTYNKDKTILCVRCATCGRKFKGEDDGEGCVKPNLTHATTTECGKRTICVMCSGIYAQLKTIPDLRAANRCLCCGVDKNKKASNAALFKVKKEKKEKKEKKEKKPKKAVEEEPKQYLTPEFVNDDEDSCDNDLSCLKNNTDLLATAMAELM
What are the official names of this protein?
Uncharacterized protein ORF122.
Protein: SCRL2_ORYSJ
Sequence: MPLVRFEVRNEVGLGDPDLYGGGGGGGGGGGGGGVGAAAKKGGEAEPKALLEGVAVAGLVGILRQLGDLAEFAADVFHDLHEQVITTSARGRKVLTRVQNIEAALPSLEKAVKNQKSHIHFTYVPGSDWHAQLKDEQNHLLSSDLPRFMMDSYEECRDPPRLYLLDKFDNAGAGACSRRHSDPSYFKKAWDMMRADKTGNFQREKKSQKIKRKGSRLREPYHGQTTPRQRNGELQRALTAVQLTSRHFATPSTDGRSLSENRSTSDVRSNPDNISRSSSFSSKARLSFTEQVLDTKPTVVPHENGHDKLSNNNLHKLSNTPLHTRLNGTSADDLGDDLKQSSLLDDMTARSPSVKWDEKAEITMSTTSVYCDDVVMDKAEHVQSKCISPEQQEIDHREMETLEQQEALHQKAKQLLVSSGLNHHDEVPSETDNYVDALNTLESETETEPELQTKSRVKPVPSLNVDVPQVELIDNIVTESPDSSVAEFPDAYQNSSMPPAPESAADFPSLSSADAPDISEPVLSGYTANPHPEVSAIATNTPVSNTEDAPGPLEISESASRAYIITLPNQSLPDSKEIPDSKAEDAPIDSPEKLEPGPSSYTPTIPIKESSIVSQNTNAENVSGDCSEGTACAISYSQHIISDKPTNEVSATNSSPDDTSSDEDTVESGGIVEVSNSQPMPLNDSLENGCATQGLPANAPTNSTGVSSVKLWTNAGLFGLEPSKPPVFGAHDGPKEDTTPGHTQPQLCHSTGCPEVHFSKPTESAQVYVPNGNSPITSSFVGKLVGICPGSTSHSSETNQSTVRTPDTVIGQTEGSTGCSTSFEHSDHKNIIGKQTSISELLESEDSAENGAEMFSKTDMTGRNNMNQVSASSFSSIAQRFLANTLQRRTPKYTDLPMSSVIVNTDANGTDESTQISSLAPNETTFEASQFEKKTENDTNGLPKSSLFSSSHYSEKSSPPLEYMKISFHPMSAFEMSKLDLDFSDENLHENADDMMLPTFQLLPGSSVPQLGSGSESEDDTFGRSYSYSSYDDLSPRLYSNSELWDQEDANGLEDHDMHNNPNQIGSFGAPISSFVEFEQMDLSGAKSTVSLTDLGDDNGLGTLDSHPAGELPNFDTLMAHQNEAFIPHNPVSLSPDEGQLPPPPPLPPMQWRTMRQVASVEEGRGSAAKEDMLESTSDLPPVHTPVQEEHLLPIAPPDQQNLLPIAPPDQQGHAKENDRKVDGVKEISNPLDIEIRASLLQQIRDKSGQQKLNGHEKSKAVGNDTKNLDEREELLQQIRSKTFNLRRTNASKTNTSSPTTANSSVVAILEKANAIRQAVASDEGGDDDSWSDI
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
SCAR-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AL9A1_MOUSE
Sequence: MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGRVIATFACSGEKEVNLAVENAKAAFKLWSKKSGLERCQVLLEAARIIKERKDEIATVETINNGKSIFEARLDVDTCWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPPGLFNVVQGGAATGQFLCHHREVAKISFTGSVPTGVKIMEMSAKGVKPITLELGGKSPLIIFSDCNMENAVKGALMANFLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIKLGDPLLEDTRMGPLINAPHLERVLGFVKLAKEQGATVLCGGEVYVPEDPKLKHGYYMTPCILTNCRDDMTCVKEEIFGPVMSILTFGTEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF
What is the function of this protein?
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro).  Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
What are the official names of this protein?
4-trimethylaminobutyraldehyde dehydrogenase, TMABA-DH, TMABADH, Aldehyde dehydrogenase family 9 member A1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FMT_BRASB
Sequence: MPLRLIFMGTPDFAVPTLLELAGHGHEIAAVYTRAPKPGGRRGLALVPTPIETEARRLGIPVVTPKTLKTEEALTAFRAHQADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGAAPINRAIMAGDAETGVMVMKMDVGLDTGDVAMAERLPITDAMTASDLHDQLARIGADLMVRAMAALERGGLTLTKQADAGVTYAAKIEKAEARIDWSKPANAVLRHIHGLSPFPGAWSEVTLDGEAVRLKILRCALADGRGEPGAVINEQLTIACADGAVRVTELQRAGKGPMKAADFLRGTRVAPGLRFG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GUAAA_THEAC
Sequence: MLKIYVVDNGGQWTHREWRVLRELGVDTKIVPNDIDSSELDGLDGLVLSGGAPNIDEELDKLGSVGKYIDDHNYPILGICVGAQFIALHFGASVVKAKHPEFGKTKVSVMHSENIFGGLPSEITVWENHNDEIINLPDDFTLAASSATCQVQGFYHKTRPIYATQFHPEVEHTQYGRDIFRNFIGICASYREIQKENFQH
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: PYRB_AZOSB
Sequence: MRNPQLNEHGELQHLLTLDGLPRQIITAILDTAAPFTEVAEREVKKLPLLRGKSVFNLFFENSTRTRTTFEIAAKRLSADVVNLNIATSSSNKGESLLDTVDNLSAMQADMFVVRHAASGAPFLIAQHLLATGRDHIRVVNAGDGRHAHPTQGLLDMYTIRHYKGDFTNLVVAIVGDVLHSRVARSQIAALTTLGVPEVRVIGPKTLLPTEVERMGVRVFHDMREGLKDVDVVMMLRLQNERMNGALLPTPQEYYKIWGLTAEKLALAKPDAIVMHPGPMNRGVEIDSAVADGTQAVILPQVTFGIAVRMAVMSMLGSH
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL31_RHOP5
Sequence: MKAEIHPDYHNITVVMTDGTEYVTRSTWGKEGDKMNLDIDPKSHPAWTGGTQQMLDRGGRVSRFQKKFSGFLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: CRT_PLABE
Sequence: MTGIKKGKNKKKNMKNDDRYKELDSLITNGSEIGNNSGRSCVKRFFKIIGNEMKNNVYVYLLSILYLCVCVMNKVFAKRTLNKMGNYSFVTSETHNIICIIVFQLLYFIYRKTSSSSVYKNESQKNFGWQFFLISLLDASTVIISMIGLTRTTGNIQSFIMQLIIPVNMYFWFMFLGYRYHLFNYLGAFIILITIAVVETFLSFETQGENSIIFNLIMISAFNTLSFSNMTREVVFKKHKINILRLNAMVVLFQFFTSLLVLPVYNIPFLKEIYMPFSEMSTNINNGLRCLFYGENTIVENCGVGMVKMCDNCEGAWKTFITFSFFNICDNLLACYIIDKFSTMTYTIVSCIQGPAITIAYYFKFLAGDAVRKPRILDFLTLFGYLFGTIIYRIGNIILEKKQVIKSQNSNDSEAELTSIETSRA
What is the function of this protein?
May regulate endogenous transporter.
What are the official names of this protein?
Putative chloroquine resistance transporter, Probable transporter cg10, pbcg10, pfcrt homolog.
What is the protein family that this protein belongs to?
Belongs to the CRT-like transporter family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Localizes to the parasite digestive vacuole, the site of chloroquine action.
Protein: PRKC_BACAN
Sequence: MLIGKRLNDRYKLLKMIGGGGMANVYLAHDDILGRDVAVKILRLDYSNNEEFIKRFHREAQSVTTLSHPNIVNMYDVGEEDGIYYLVMEYVPGQTLKQYIIERGMLPIGEALDIMEQLTSAMAHAHHFEIVHRDIKPHNILIRADGVIKVTDFGIATATSATTITHTNSVLGSVHYLSPEQARGGIANKQSDIYSLGIVMFELLTGRQPFSGESAVAIALKHLQSEIPSPKRWNENIPQSVENIILKATAKDPFHRYQSANAMKRDIETALYPERINEQPFYIPEDMEATKAIPIIQQEQLFENVTDETIVLKGSKVDEQIRKEETDLSKKKKRSNKWLKILITTFLLLAIGITLALTVIPGFFIPKDVKVPDVAGMKYTTAVNTLVEKGFEVTEPNIVYTDDVETGDVIKTDPVAGRVVKENSKITIYQSGGKKKSKMIDFTGKDLESIRTELEEKYKQVTVYYIEDDRPKGAIVEQIPTSDQMVVEAEQELKIWVSKGPYQIRPGDFSRWTENSVTGYLNERKLTPDIKREYSDTVDKGLVISQSPKPGTPLKEGDKVTIIISEGPKPKVTKTVKVDNISIPYESSIIGEKKPQTIEIYKEDMQQKMDRPIETRTISESATISLEFVIQEDTKGRYKIVRDGVTIIDKEVPYPTQ
What is the function of this protein?
Protein kinase that is responsible for triggering spore germination in response to muropeptides, signaling bacteria to exit dormancy.  PrkC is thus a germination receptor that binds peptidoglycan fragments containing m-Dpm (meso-diaminopimelate), which act as spore germinants.  Probably autophosphorylates and phosphorylates FusA (EF-G, elongation factor G); the latter modification is likely necessary for germination in response to peptidoglycan.
What are the official names of this protein?
Serine/threonine-protein kinase PrkC, Ser/Thr-protein kinase PrkC.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Spore membrane; Single-pass type II membrane protein. Note=Is associated with the inner membrane of the spore.
Protein: GAPR1_HUMAN
Sequence: MGKSASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSRGQCGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKASASDGSSFVVARYFPAGNVVNEGFFEENVLPPKK
What are the official names of this protein?
Golgi-associated plant pathogenesis-related protein 1, GAPR-1, Golgi-associated PR-1 protein, Glioma pathogenesis-related protein 2, GliPR 2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.
Protein: PDUL_LISMO
Sequence: MNNELITSLIEEVTRRALLETGVEVEASGRHVHLDRETVDALFGPGYELTHFRDLSQPGQYVCKERISIVGPKSVIHNVVILGPIRKKTQVEISSTDGTALGIKAPVRESGDIAGTPGILLLSAKNSVQLSEGLIVAKRHIHMTPADAEKQQVSQSEIVQVKINGDRPLIFDDVVVRISPDFATYMHIDYDEANACGFKKGIRGQIIKKTKAK
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: MURB_PARXL
Sequence: MSQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGSNVVLTGDFGGLVLLVALRGRRVVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLALIPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVELDAQACRFGYRDSFFKREGRDRFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLELGNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAAVHERQALVLVNRGGASGAEVLALAKAIQRDVRERFGVELEPEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_LACJO
Sequence: MSIKAEEISALIKQQLEKYDDKLNVNEVGTVTYVGDGIARAHGLNNVLSSELLQFSNGSYGIAQNLEANDVGIIILGRFDDIREGDQVKRTGRIMEVPVGDQLIGRVVNPLGQPVDGLGEIKTDKTRPIESKAPGVMDRQSVNQPLQTGIKAIDALVPIGRGQRELIIGDRKTGKTALALDTIINQKGQDVICIYVAIGQKESTVKNSVETLKRFGAMDYTIVVEAGPSEPAPMLYIAPYAGTAMGEEFMYNGKDVLIVFDDLSKQAVAYREISLLLRRPPGREAYPGDVFYLHSRLLERSAKLNKKLGGGSMTALPFIQTQAGDISAYIPTNVISITDGQIFLEADLFFAGTRPAINAGESVSRVGGSAQIKAMKKVAGTLRVDLASYRELESFAQFGSDLDQATQAKLNRGRRTVEVLKQPLHKPLPVEDEVLILYALTHGFLDAIPVPDIQRYELELYDYFASNYNDLLDVIRTTGDLPEEDKLNEALKNFNEGFSISKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.