PharMolix/UniProtQA huggingface dataset:
Protein: NIKR_DESVM
Sequence: MGRTIRFGVSLDSDLLEKFDALCDDRCYQTRSEAIRDLIRNTLVQQEWEDTDREIAGTLTIVYDHHKSDLAQRLTEIQHDHHGIIITSLHVHLDHHNCLEVLVLKGPGADVRTLSQRLISTKGVKHGKLSLTTTGQDLT
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: 18K2_MYCIT
Sequence: MLVRSDPFRDLDRFTQQLSGTAARPAAMPMDAWRDGEQFVVEFDLPGIDEQSLDLDIERNVVTVRAERPDVDPSREMLATERARGVFSRQLVLGDNLDTEHIDACYDAGVLRLRIPVAEKAKPRKIAVNRGDRQQTAISA
What is the function of this protein?
Not known.  This protein is one of the major immune reactive proteins in mycobacteria.
What are the official names of this protein?
18 kDa antigen 2, 18 kDa antigen clone MINTC541.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: PSBJ_PSINU
Sequence: MANTTGRIPLWLVGTVTGTLVIGLMGIFFYGAYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TPIS_STRP6
Sequence: MSRKPIIAGNWKMNKNPQEARAFVEAVASKLPSTDLVDVAVAAPAVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDYFHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQVASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPENVKDYMACPDVDGALVGGASLEAGSFLALLDFLN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_CROS8
Sequence: MIALIQRVTHASVRVGDEVTGEIGPGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDEQGKMNLNVQQAGGSVLVVSQFTLPADTEKGLRPSFSRGAPPEQAQALYDYFVSRCRAAGMTTETGRFAADMQVSLTNDGPVTFWLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF15_SACOF
Sequence: MLIVLFRSKDIRGGRFVRPILIFRTKRSWILFRIGPERRREAEMPTDLCLFSNSPDPIVPVFGTSSAKVTEWVSHQSNPFDKSGVILDIIFYIYRNIIE
What are the official names of this protein?
Putative uncharacterized protein ycf15, ORF99.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NEUS_CHICK
Sequence: MYFLGLLSLLVLPSKAFKTNFPDETIAELSVNVYNQLRAAREDENILFCPLSIAIAMGMIELGAHGTTLKEIRHSLGFDSLKNGEEFTFLKDLSDMATTEESHYVLNMANSLYVQNGFHVSEKFLQLVKKYFKAEVENIDFSQSAAVATHINKWVENHTNNMIKDFVSSRDFSALTHLVLINAIYFKGNWKSQFRPENTRTFSFTKDDETEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMIVLSRQEVPLVTLEPLVKASLINEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKGLGITEVFSRSADLTAMSDNKELYLAKAFHKAFLEVNEEGSEAAAASGMIAISRMAVLYPQVIVDHPFFFLVRNRRTGTVLFMGRVMHPEAMNTSGHDFEEL
What is the function of this protein?
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin (PubMed:9442076).  May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system.  May protect neurons from cell damage by tissue-type plasminogen activator (Probable).
What are the official names of this protein?
Neuroserpin, Axonin-2, Peptidase inhibitor 12, PI-12, Serpin I1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Perikaryon.
Protein: PCYAA_EUGGR
Sequence: MYILVWKEGQQIRTFQDLEECGQFQTASNITDGQIFSINVTPTMSKGGETGETQLRRLMYLSASTEPEKCNAEYLADMAHVATLRNKQIGVSGFLLYSSPFFFQVIEGTDEDLDFLFAKISADPRHERCIVLANGPCTGRMYGEWHMKDSHIDNITKHPAIKTILFQIARSFSSMWSYLPKNAANMLLLGKNPNKQAPEPMSVVVTFIYLVEFSSILAHPGLTEQCADILAAFVDACVRNVEGTGGQVAKFITGICMAYWPINRAEDALVGLQQLSEDLAELRSQQPPGSALSLIYSRCGVHYGRALLCNAGFRKADFTLLGDCINTASRITSLSVKLKVPLLLSFEVRCLLGDEMREELESSGLHKVKGRDKPVQVYQFNAPELDSAMVRAKIEQFNPGRYRALCPVKPYESLHPAQRPPIFDDTPRENQPKLSQVQRRDSLVDRLSLIAKLAFPSSMMAGGEGQLITLTYISQAAHPMSRLDLASIQRIAFARNESSNITGSLLYVSGLFVQTLEGPKGAVVSLYLKIRQDKRHKDVVAVFMAPIDERVYGSPLDMTSATEEMLATFPPLQDVLSQLAKSFISLETYVPSTVVRYLTAGNNPRNLQPVSVEVVMLATDICSFTPLSEKCSLTEVWTICNTFIDACTSAICNEGGEVIKLIGDCVTAYFPPTGADNAVHACQEIVSFCAQLRDAFHDVLDCRSVVACGVGLDFGQVIMAQCGSLGMTEFVVAGEVSARVMEVEALTREAGRAIVITEPVADRLSPKLRDTGIVPCQEGVDGVPCYGILGPEWELDVATIKKNIYGFHDARALAAMKKVDDGTNAPGRGAPAGGIPSSPKVRPPGRTNSVSSYTPDPNEALDPRMAESVFLDMCHQRGDTANNSIAVKLRQAANDDRLDLGRMLQGPHELMPVMQAIKHLTNLRMLNMSDNFVDDNNVGELVESCIPMRSLQVLDLSNNPGLTKVIALKRLIKHNTQVREILLNGTRIAPTEQRKLQSSMNVNRLCASTDLKGSHKYEH
What is the function of this protein?
Acts as a blue light photoreceptor for the step-up photophobic response.  Mediates photoavoidance.
What are the official names of this protein?
Photoactivated adenylate cyclase subunit alpha, Photoactivated adenylyl cyclase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Paraflagellar body, flagellum and paraxonemal bodies (PABs).
Protein: Y489_RICPR
Sequence: MYLLSFILGGLNTLLRQLRLSISSIDFYKDVYKNYQGYGIKYLFTLSFIPSIIYCIFILNYIITLKDYFNGTSSSKVTDNIEYIINQLPKIKYNNSKISVEEVEPIYLYSKNNNKIFVIDTKNQVSNQEKSKVPFVLEENKLKINLVSNTKKHFPSIVNYSEIFKQNEVILTPEIIKKYFADNLLYAPNLFIFFGTPVIILFWFVTFLLERSIIVLLVYGLANLLTTKTSIQTSIRLVMFSSGIPIILQPVIIILIPELSILIQLLQMFTTFLVFVAILQINKSLSHI
What are the official names of this protein?
Uncharacterized protein RP489.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATA_AGRRK
Sequence: MGSLSIWHWLIVLAIALLLFGRGKIPELMGDVAKGIKSFKKGMNDDEETPPPAQSTTSRTVEHKADESK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PPK5_HOSCA
Sequence: SGETSGEGNGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, HosCa-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROB_ROSDO
Sequence: MAALTDADCLVVKIGSALLVDRDAGGLRQAWLASLAQDVAWLTRQGVKVVLVSSGSIALGRGILKLSDTDLPLEQAQAAAAVGQIRLARAYEEVLAPHGITTGQVLMTLDDSSNRRRYLNSRATLKQLLSMGVVPIVNENDTIATDEIRFGDNDRLAAQIAVTVGADQLVLLSDVDGFYSANPNIDPTAQRFDEIGEITPEIEDMAGDACSGLSKGGMKTKLMAAKIATAAGCRMAITEGVVLNPLRALNEGAAATWFRADTDPQAARKGWIAAMKPKGTVHLDSGALAALRSGKSLLPAGVSHITGHFQRGDPVAIADGAGHTVGHGLVRYTAEEAGRIMGRKSNEIESVLGYPARAALIHRDDMALTIQNGD
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3_SOLST
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTELRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DPYL3_XENTR
Sequence: MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHLQMPYRGMTTVDDFFQGTKAALAGGTTMIVDHVIPEPEASLTEAFEKWREWADGKTCCDYSLHVDITHWNDSVKQEVEALVKQKGVNSFMVYMAYKDLYQMSNTELYEVFTFLGGLGAIAQVHAENGDIIAQEQNRMLELGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSSVDLISQARKKGYVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQVTGSAHATFSTAQKAIGKDNFTLIPEGTNGIEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKSHHSAAEYNIFEGMELRGAPLVVICQGKIMMEDGTLHVTQGTGRFIPCSPFPDYVYKRIKARTKMAELHAVPRGMYDGPVYDLASTPKAGTPAGSTKGSPTKQTAPVRNLHHSGFSLAGNQGDESGVRSASRRIVAPPGGRSNITSLS
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
What are the official names of this protein?
Dihydropyrimidinase-related protein 3, DRP-3, Dihydropyrimidinase-like 3.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, growth cone.
Protein: TLC2_ARATH
Sequence: MEGLIQTRGILSLPAKPIGVRRLLQPSHGLKQRLFTTNLPALSLSSNGHKKFQAFQQIPLGISVSHKERSRGFICKAEAAAAGGGNVFDEGDTAAMAVSPKIFGVEVTTLKKIVPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIVYFGAFGFVMYPLSNLIHPEALADKLLATLGPRFMGPLAIMRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNMRKNLGPGVDGWAVSLKAMMSIVVGMGLAICFLYWWVNRYVPLPTRSKKKKVKPQMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGIATFTMMLLSQYVFKKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILTFGSLANSTPYLGVILLGIVTAWLAAAKSLEGQFNTLMSEEELEREMERASSVKIPVVSQEDAPSGETTSQLSEKSTPTGI
What are the official names of this protein?
ADP,ATP carrier protein 2, chloroplastic, ADP/ATP translocase 2, Adenine nucleotide translocase 2.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc (TC 2.A.12.2) family.
Protein: IER5_HUMAN
Sequence: MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDMNPWSTAIVAF
What is the function of this protein?
Plays a role as a transcription factor (PubMed:22132193, PubMed:25355627).  Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed:25355627, PubMed:25816751).  Mediates negative transcriptional regulation of CDC25B expression (PubMed:22132193).  Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A (PubMed:25816751, PubMed:26496226).  Involved in the regulation of cell proliferation and resistance to thermal stress (PubMed:22132193, PubMed:25355627, PubMed:26496226).  Involved in the cell cycle checkpoint and survival in response to ionizing radiation (PubMed:19238419, PubMed:22132193).  Associates with chromatin to the CDC25B promoter (PubMed:22132193).
What are the official names of this protein?
Immediate early response gene 5 protein.
What is the protein family that this protein belongs to?
Belongs to the IER family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic (PubMed:25816751). Translocated in the nucleus during heat shock (PubMed:25816751).
Protein: RBM4_HUMAN
Sequence: MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRSGRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAASVYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRARYSAF
What is the function of this protein?
RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation.  Modulates alternative 5'-splice site and exon selection.  Acts as a muscle cell differentiation-promoting factor.  Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation.  Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin.  Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs.  Required for the translational activation of PER1 mRNA in response to circadian clock.  Binds directly to the 3'-UTR of the PER1 mRNA.  Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation.  Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress.  Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions.  Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs.  Associates with miRNAs during muscle cell differentiation.  Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
What are the official names of this protein?
RNA-binding protein 4, Lark homolog, hLark, RNA-binding motif protein 4, RNA-binding motif protein 4a.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus speckle. Cytoplasm. Cytoplasmic granule. Note=Undergoes continuous nucleocytoplasmic shuttling. Upon nuclear import colocalizes with SR proteins in nuclear speckles. Arsenite stress-induced phosphorylation increases its subcellular relocalization from the nucleus to the cytoplasm and to cytoplasmic stress granules (SG) via a p38 MAPK signaling pathway. Primarily localized in nucleus and nucleoli under cell growth conditions and accumulated in the cytoplasm and cytoplasm perinuclear granules upon muscle cell differentiation.
Protein: RL24_BUCAI
Sequence: MALKLRRNDSVVILTGKDKGKTGIIKNILSLNQVIVKGLNLIKKHQKPVPSQNKSGGIIEKEAPIHISNIAILNPESNKADRIGFRFEEGRKVRFFKSTGKTIQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y1409_STAAM
Sequence: MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETLSEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEALKNRFVVIHVDYIDGDILKNVIKEQSLLQDDKQIEQIIKFNEDLRTMSKQGQISEEAASIRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF
What are the official names of this protein?
Uncharacterized protein SAV1409.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: LIPB_MAGSA
Sequence: MNYPVEWRISDSPVDYPQAIAAMEERVAAIRAGTAPELVWLLEHPPLYSAGTSADPRDLVDPGRFPVYETGRGGQYTYHGPGQRVAYVLLDLKRRGADVRVYVCNLEEWLIRTLARFVVKGERRTGRVGIWVDRGGGREDKIAAIGVRVRHWVTFHGIALNVDPDLSHFEGIVPCGIREHGVTSLWDLGLTPTMDDVDCALMATFPEVFGAD
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L_EBLV2
Sequence: MIDPLEVYDDPVDPVEPEIDARSNSVVPNILRNSDYNLNSPLIEDPSKLMLDWLITGNKPARLNLTDNSLRSYKVLKSYFKKLDVGSLRVGGLGAQSMMSLWLHGAHSESTRSRKCLSDLALFYQRSAPIEKLLNYTLENRGLAIPTDGVLSSLKKVNYDRAFGRYLGNLYSSYLFFHVIILYMNALDWEEEKTILALWKDLNSVDIKKDQVKFRDQIWGSLLVTKDFVYSQSANCLFDRNYTLMLKDLFLSRFNSLLILLSPPEPRYSEDLISQLCQLYIAGDNVLSTCGNSGYDVIKMLEPYVVNSLVQRAEGFRPMIHSLGDFPTFIKDKVSQLEGTFGPSARNFFFVLDQLDNIHDLVFVYGCYRHWGHPYIDYRKGLSKLYDQVHVKKVIDGDYQECLASDLAKRILRWGFDKYSKWYLDPKLLEKDHPLIPYIQTQTWPPKHIVDIVGNTWHKLPITQIFEIPESMDPSEILDDKSHSFTRTKLASWLSDHRGGPVPSEKVIITALSRPPVNPREFLKSIDLGGLPDDDLIIGLKPKERELKIEGRFFALMSWNLRLYFVITEKLLANYILPLFDALTMTDNLNKVFKKLIDRVTGQGLQDYSRVTYAFHLDYEKWNNHQRLESTKDVFSVLDYVFGLKKVFSRTHEFFQKSWVYYSDRSDLIGLWEDQIYCLDMSDGPTCWNGQDGGLEGLRQKGWSLVSLLMIDRESQTRNTRTKILAQGDNQVLCPTYMLSSGLTQEGLIYELDSISRNALSIYRAIEEGASKLGLIIKKEETMCSYDFLIYGKTPLFRGNILVPESKRWARVSCISNDQIVNLANIMSTVSTNALTVAQHSQSLIKPMRDFLLMAVQAVFHYLLFSPILKDRVYKILSAEGDNFLLAMSRIIYLDPSLGGVSGMSLGRFHIRQFSDPVSEGLAFWKEIWSSSSESWIHSLCQEAGNPDLGDRSLESFTRLLEDPTTLNIRGGASPTILLKEAIRKALYDEVDKVENSEFREAILLSKTHRDNFILFLKSIEPLFPRFLSELFSSSFLGIPESIIGLIQNSRTIRRQFRRSLSRTLEESFFNSEIHGINRMTQVPQRVGRVWNCSAERADLLREISWGRKVVGTTVPHPGEMLVLLPKSSVSCVCKQTGEDSPRISVSVLPSFDQSFFSRGPLKGYLGSSTSMSTQLFHAWEKVTNVHVVKRALSLKESINWFIARDSNLAQTLIRNITSLTGPQFPLEETPVFKRTGSALHRFKSARYSEGGYSSICPNLLSHISVSTDTMSDLTQDGKNFDFMFQPLMLYAQTWTSELVQKDIRLRDSTFHWHLRCLKCIRPIDDIILDAPQVFMFPDVSKRISRMVSGAVPQFQRLPEINLKPGKFEALDSKDKSRHIGTAQGLLYSILVAIHDSGYNDATIFPMNIYSKISPRDYLRGLSRGILIGSSICFLTRMTNININRPLELISGVISYILLRLDNHPSLYVMLREPSLRSEIFSIPQKIPAAYPTTMKEGNRSVLCYLQHVLRYERDVITASPENDWLWIFSDFRSAKMTYLTLVTYQSHILLQKIEKNLPKQMRIRLRQLSSLMRQILGGHGEDTLDSDEDIQGLLRDALQRTRWVDQEVRHAAKTMTGDHSPSKKVSRKAGCSEWICSAQQVAISTSSNPAPTSEMDVRALSRRFQNPLISGLRVVQWATGAHYKLKPILDNLEAYPSLCLVVGDGSGGISRTVLSMFPDAKLVFNSLLEVNDFMASGTHPLPPSAIVSGGDDIVSRVIDFGSIWEKPSDLRNLSTWRYFQSIQTVNNMSYDLIVCDAEVTDIPSVNKITLLMSDFSLSINGPLNLIFKTYGTMLVNPDYKAIQHLSRAFPSVTGYITQMTSSFSSELYLKFSKRGKFFRDAEYLTSSTLREMSLVLFNCSSPKSEMQRARSLNYQDLVRGFPEEIISNPYNEMIITLIDSEVESFLVHKMVDDLELQRGTLAKMSIIIAIVMVFSNRVFNVSKPLTDPMFYPPSDPKILRHFNICCSTLMYLSTALGDVLNFARLHELYNNPITYYFKKQVIRGSIYLSWSWCDTTSVFKKVACNSNLSLSSHWIRLIYKIVRTTRLAGSSNDLSKEVEKHLKGYNRWISFDDIRSRSSLLDYSCL
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: COQ7_ACIET
Sequence: MDTLLIAADSALRTLFARPRAGEPSPARSLPAVDLSVEQRRLSSALMRVNHVGEVCAQGLYMAQSCVTRDPQLRSDLLAAAREETDHLAWTRERLDALGSRPSLLNPLWFAGAFAIGLVAARVSDQASLGFVVETERQVSAHLQGHLRRLPEADLPSRAIVDRMQRDEERHAAQAQAAGALPLPPPARWLMKAAAKVMTTTAHHI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SDHE_PSEU2
Sequence: MVEDVELNRLYWHSRRGMLELDVLLVPFVREVYPHLNDVDRDLYRRLLTCEDQDMFGWFMQRAESEDAELQRMVRMILDRVQPQ
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVE_HELPJ
Sequence: MPNLENLDWKNLGFSYIKTDFRFIATYKNGSWSQGELVSENALQLSEGSPVLHYGQACFEGLKAYRSQKGKALLFRPLENAKRLQTSCERLLMPKVSEELFLKACAEVIKANQKWLAPYKSGASLYLRPFVIGVGDNLGVKPASEYLFIVFCAPVGAYFKGGIEKGGARFITTAFDRAAPKGTGGVKVGGNYAASLLAHKIATEQGYDDCIYLDPTTHTKIEEVGAANFFGITHDDAFITPHSPSILPSVTRKSLMVLAKEHLKLKVEEREILIDELGAFKEAGACGTAAIITPIKEIAHNNKSYSFEAPGNITKQLYDLLLSIQQGEQEAPKDWIFEVG
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase, BCAT.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: IF4G1_ARATH
Sequence: MQQGDQTVLSLRPGGGRGNRLFGSSSSSSSLSFGSLSSSDLPLLRPHGGAPASSFPFKGGDSRFDGRERVKYTREQLLELKETTQLSDEILRVQRETAAELFGEEGTWARGESVVSNLVPVQSASRFSEPDSRDWRSRSTQPPPSGEERSWDNLREAKDSRYVEASQYNRQDQPNSQFSRANISSNQGGGPAPVLVKAEVPWSARRGNLSENDRVLKTVKGILNKLTPEKYDLLKGQLIESGITSADILKGVITLIFDKAVLEPTFCPMYAKLCSDINDQLPTFPPAEPGDKEITFKRVLLNICQEAFEGASQLREELRQMSAPDQEAERNDKEKLLKLKTLGNIRLIGELLKQKMVPEKIVHHIVQELLGADEKVCPAEENVEAICHFFKTIGKQLDGNVKSKRINDVYFKRLQALSKNPQLELRLRFMVQNIIDMRSNGWVPRREEMKARTITEIHTEAEKNLGLRPGATANMRRGMVSSGGPVSPGPVYPGGRPGAGGLMPGMPGTRRMPGMPGVDNDNWEVPRTRSMSRRDGPGPLHSPAVSKSASMNTRLLPQGSSGIMSGKTSALLQGSGSVSRPVTVSAERPAQSVAPLTVPVPVEKPQPSGPKLSEEVLQRKTKSLLEEYFNVRLLGEALQCVEELGLPSYHPEFVKEAISLSLEKSPPVVEPIATLLEYLLSKKVVAPKDLETGFLLYGAMLDDIGIDLPKAPNNFGEIVGKLILAGGVDFKLVREIIGKMEDDRFQKMVVDAAVRIVESSEQGKSLLASQAADIEACRNL
What is the function of this protein?
Plays a role in the accumulation of some potyvirus during viral infection.
What are the official names of this protein?
Eukaryotic translation initiation factor isoform 4G-1, eIF(iso)4G-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.