PharMolix/UniProtQA huggingface dataset:
Protein: DPOG_YEAST
Sequence: MTKLMVRSECMLRMVRRRPLRVQFCARWFSTKKNTAEAPRINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFTEMVARPAEWLRKPGWVKYVPGMAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSPFICGGDDPAALIPLNTLNKEQVIIGHNVAYDRARVLEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMKNNKKKEAEVESEVHPEISIEDYDDPWLNVSALNSLKDVAKFHCKIDLDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPDFYLKDPWLSQLDWTTKPLRLTKKGVPAKCQKLPGFPEWYRQLFPSKDTVEPKITIKSRIIPILFKLSWENSPVIWSKESGWCFNVPHEQVETYKAKNYVLADSVSQEEEEIRTHNLGLQCTGVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSESELAHQALQINSSGSYWMSARERIQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFNVHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKGKTKRSKLFKKFWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKNLRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSNKTAIPHGEALDINQLLDKSNSKLGKPNLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQSDKRDVNRLEDEYLRECTSKEYARDGNTAEYSLLDYIKDVEKGKRTKVRIMGSNFLDGTKNAKADQRIRLPVNMPDYPTLHKIANDSAIPEKQLLENRRKKENRIDDENKKKLTRKKNTTPMERKYKRVYGGRKAFEAFYECANKPLDYTLETEKQFFNIPIDGVIDDVLNDKSNYKKKPSQARTASSSPIRKTAKAVHSKKLPARKSSTTNRNLVELERDITISREY
What is the function of this protein?
Involved in the replication of mitochondrial DNA.
What are the official names of this protein?
DNA polymerase gamma, Mitochondrial DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CSN1_NEUCR
Sequence: MDDRKLAFFTAIEDQGGVIVKGRTRFERLFHIGRSSVPLCVDALKAAVQEAKAGSDILRYQMAVNSLFQAAPNEPEALLDKAWMESKEKENRDTTAHLQAELQGYKNNLIKESIRMGNEDLGKHFEAIGDVEAAMDSFWKMRTEVSSTEQLVDLGKLLVRVAIERRDWKSIGNHLKPLNSVNDSDPKAKALKTYSKIANGIAALGQERYKEAAFCFVEASSGVPPEIYNQIASPNDVAIYGGLLALATMDRHELQANLLDNDSFREFLQREPHIRRAITQFVNGRYAACIEILESYRPDYLLDIYLQKHVPKLYADIRTKSIVQYLKPFSCVRLDTMQKAFNGPGPSIEDELFTMIKDGKLNARIDAINKSKALQTLENYEKQALDRIRRMNIMAADLEVKGSRKPGGMNDIPFSMTTDDTVSLA
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD-1) complex.
What are the official names of this protein?
COP9 signalosome complex subunit 1, CSN complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the CSN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OCTC_MOUSE
Sequence: MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQLMNTAHL
What is the function of this protein?
Beta-oxidation of fatty acids.  The highest activity concerns the C6 to C10 chain length substrate.
What are the official names of this protein?
Peroxisomal carnitine O-octanoyltransferase, COT.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ATAL_ASPTN
Sequence: MSTPTSFTFNIAYSVPINKDPSQPTLTLEEFWRGLHRGSEKPQLFAEYVADTEVLPNSKSANEFQRKLIMANGAVHTAKGVELLQDVRNADGLLDDGPDALYLTAVYELHVPDVEPGSERAKEIEREYAQLALGAARTVVETIRRWKVEGGLEDA
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of acetylaranotin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide-bridged cyclic dipeptide (PubMed:23586797).  The first step of acetylaranotin biosynthesis is performed by the NRPS ataP which produces diketopiperazine cyclo-L-Phe-L-Phe via the condensation of 2 phenylalanines (L-Phe) (PubMed:23586797).  The ataC domain of ataTC then catalyzes the formation of bishydroxylation of cyclo-L-Phe-L-Phe (PubMed:23586797).  The glutathione S-transferase domain ataG in ataIMG further catalyzes the conjugation of two glutathiones to the bishydroxylated intermediate (PubMed:23586797).  Next, the dipeptidase ataJ removes the Glu residues (PubMed:23586797).  The following step is performed by the carbon sulfur lyase domain ataI of ataIMG which may convert the bis-cysteinyl adduct to yield an epidithiol intermediate (PubMed:23586797).  The ataT domain from ataTC then catalyzes the oxidation of the free dithiols, followed by a cyclization step catalyzed by the cytochrome P450 ataF (PubMed:23586797).  AtaF probably acts as an epoxidase to promote a dual epoxidation formation at C8 and C9 along with C8' and C9', followed by the spontaneous nucleophilic attack of the amide nitrogens N10 and N10' to yield an intermediate with the pyrrolidine partial structure (PubMed:23586797).  The final steps of acetylaranotin biosynthesis involve the acetylation and ring rearrangement of an epitetrathiodiketopiperazine intermediate to produce acetylaranotin (PubMed:23586797).  AtaH probably catalyzes the acetylation of epitetrathiodiketopiperazine to produce a diacetate and ataY is responsible for the formation of the dihydrooxepin moiety that converts the diacetate intermediate to acetylaranotin via acetylapoaranotin (PubMed:23586797).  Both enzymes could function independently in the absence of the other (PubMed:23586797).  The specific function of ataL within the pathway has still to be determined (PubMed:23586797).  The acetylaranotin bis-thiomethyltransferase ataS located outside of acetylaranotin gene cluster is the main thiomethyltransferase responsible for converting acetylaranotin and its related intermediates to their methylated forms (PubMed:30096370).
What are the official names of this protein?
Acetylaranotin biosynthesis cluster protein L.
Protein: GUAA_STAA3
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: BETB_XANCB
Sequence: MPRFPDQLLYIGGRYVPARGGHTFEVVNPATGEVLANVHNADADDLDAAVDSAKAGQRHWAALTVVERSRILLRAVALLRERNDALAELETLNTGKPLSETRSVDIVTGADVLEYYAGVAQALQGVQVPLREGSFFYTRHEPLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGVFNVLPGDGASVGHALTEHPEIEKISFTGGTATGRKVMASASSSSLKDVTMELGGKSPLIVCADADLDLAADIAMMANFYSSGQVCTNGTRVFVPRALRTAFEARLLARVQRIHIGDPLDERTTFGPMVSAAHMQRVLEHIEQGKAEGARLLCGGERLRDGALAQGCYVAPTIFSDCTDVMTIVREEIFGPVLSLLTYDDEDEAITRANATSYGLAAGVVTPDLSRAHRLIHRLEAGICWINTWGESPAPMPVGGYKQSGVGRENGLATLQAYTRTKSVQVELERYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: OTC_STRS2
Sequence: MTNVFKGRHFLAEKDFTRAELEWLIDFSAHLKDLKKRNIPHRYLEGKNIALLFEKTSTRTRAAFTVASIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQKMVEELAEFSGVPVWNGLTDAWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEVVALAEGFAKESGARVLITDNADEAVKGADVLYTDVWVSMGEEDKFAERVALLKPYQVNMELVKKAENENLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGDPFVPRV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_ELUMP
Sequence: MQLENIKKLQDLDVKGKTVLVRVDYNVPLKDGKVDNNKRIVASEKTVKYLLDNNCKVVLMSHLGRPKGKVASEFSLAPVATEVANVFGVKVHFASDCIGEPAAKTIAEAKNGEIVLLENLRFHPEEEKNDETFAAQLAKNGEVFVQEAFGTVHRAHASTSAVTKFLNGGIGYLVQKEVQFLGDALAKPNRPFAAIIGGAKVSDKIMVLNTLLSKVNVLVIGGGMAYTFLKAQGYTTGKSLLEEDKVEEANKILATAKEKGVEILLPVDHVCSTEFSNESPVMTTENANIPEGQMGLDIGPKTIALFDKKLLECKTIFWNGPVGVFEMSNFEKGSFAIASSMVEATKLGATTIIGGGDSLNVLKKAKIKTDLLSHCSTGGGASMEFVEGKELPGLTALAK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMC5_DANRE
Sequence: MASSFWKGVVGIGLFALAHAAFSAAQHRSYMRLTEKENETLPIDIVLQTLLSFVITCYGIVHISGEFKDMDASSELKNKTFDTLRNHPSFYLFNHRGRVLFRTPEQEPSTPNAQALPSNPLRLRKLENFH
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (By similarity).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.  May be involved in Mg(2+) transport (By similarity).
What are the official names of this protein?
ER membrane protein complex subunit 5, Membrane magnesium transporter 1.
What is the protein family that this protein belongs to?
Belongs to the membrane magnesium transporter (TC 1.A.67) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: NIPA4_ARATH
Sequence: MAESSGSWRDSYKGMSSDNIKGLVLALSSSLFIGASFIVKKKGLKKAASTGTRAGVGGYSYLYEPLWWIGMTTMLLGEIANFAAYAFAPAILVTPLGAVSIIISAVLAHIILREKLHIFGILGCALCVVGSTTIVLHAPQEREIDSVIEVWNLATEPAFMFYASLVIGAAVFLIIRFVPQYGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWIFTLVVLTCVVTQLNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDWDRQNGTQIVTEICGFVTILSGTFLLHRTKDMVEGSSVILPLRISKHINEEEGIPLRRQESLRSP
What is the function of this protein?
Acts as a Mg(2+) transporter.  Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
What are the official names of this protein?
Probable magnesium transporter NIPA4.
What is the protein family that this protein belongs to?
Belongs to the NIPA (TC 2.A.7) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Recruited to the cell membrane in response to low extracellular magnesium.
Protein: PLS3_PHAJA
Sequence: FLSLIPHAINAISAIANHL
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Phylloseptin-J3, PLS-J3, PS-J3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_PROM9
Sequence: MIEPLLCGIVLGLVPITLLGLFVSAWNQYRRGSGMLDID
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RL16_BACVZ
Sequence: MLLPKRVKYRREHRGKMRGRAKGGTEVHFGEYGIQALEASWITNRQIEAARIAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKVLFEISGVSEEVAREALRLASHKLPIKTKFVKREEIGGESNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: VU10_HHV6U
Sequence: MEIVTYKTVSARSPTVTWSSGFGRAIASIQKRNQDNIRKPLRFYTGLLHCLIKQYEHCLVPPNKSIRFDKGKIEVAALILDLGHQVLGRQIHVRQRIYSWTSITLPKLFTPKELYFLIASPEEENIAFNPTITKGGWISGSFSYPVDYRSNFSLTGMSANILMVPFVPYKYPLNYARFISSIDLMILNEQFPEHECGDIQILKQRNYLYLGVIKNLTWKKSVTGTGQTAPHRILKASFIGSWPDTSLPDRVALRFFNNTRFTIHCHEFSINIENLGLVKNKEKVFGTLATVCCEQIPSLLTTENLPKYLIVQFEVVTQIEEPEPLLFSSNPKLYFTGDVLNATIQLQHNPNYYELLVHAPYDIHFYPSRCHIVILPIRYFTKPDKQILISGYQNEGFFETQVMLWAPGTPLHITLRSFSPNLILPQSTKRRNRKAV
What are the official names of this protein?
U10 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U10 family.
Protein: C76C4_ARATH
Sequence: MDIISGQALFLLFCFISSCFLISTTARSRRSSGRAATLPPGPPRLPIIGNIHQVGKNPHSSFADLAKIYGPIMSLKFGCLNSVVITSPEAAREVLRTHDQILSGRKSNDSIRCFGHEEVSVIWLPPSSARWRMLRKLSVTLMFSPQRTEATKALRMKKVQELVSFMNESSERKEAVDISRASYTTVLNIISNILFSVDLGSYDSKKSNEFQDTVIGAMEAAGKPDAANYFPFMGFLDLQGNRKAMRGLTERLFRVFRGFMDAKIAEKSLGNYSKDVSNRDFLDSLLILNEGDEAELDNNDIEHLLLDMFTAGTDTSSSTLEWAMAELLRNPKTMVKAQAEMDRVLGQNSVVQESDISGLPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVPKDTQVLVNVWAIGRDPSVWENPSQFEPERFMGKDIDVKGRDYELTPFGGGRRICPGLPLAVKTVSLMLASLLYSFDWKLPNGVVSEDLDMDETFGITLHRTNTLYAIPVKKQTIN
What are the official names of this protein?
Cytochrome P450 76C4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LPXB_ACTP2
Sequence: MMTKEAPLIALVAGEISGDILGAGLINALKLHYPNARFIGVAGPRMIQAGCETLFDMEELAVMGLAEVVKHLPRLLKRRKQVIETMLAEKPDIFIGIDAPDFNLTVEEKLKASGIKTIHYVSPSVWAWRQNRVHKIARATNLVLAFLPFEKAFYDRFNVPCRFIGHTMADTIALKPNRAEACVGLNLDEAQRYLAILVGSRASEVGFLAEPFLKAAQILKQQYPDLQFLVPLVNDKRIAQFEQIKAQVAPELSVHILKGNARQAMIAAEASLLASGTAALEGMLCKSPMVVGYKMKAMTYWLAKRLVKTKYISLPNLLADEMLVPELIQDECNPENLAWYLGNYLADDADHRKQRNELKQRFTELHKLIQCDADAQAAQAVVDVLEANTSDQN
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RL35_ECOLU
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: UD12_RAT
Sequence: MDTGLCAPLRGLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHMKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEPQHFVKTFFETMASIKKFFDLYANSCAALLHNKTLIQQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGIDYEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLTLKYICHLSITPYESLASELLQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
What is the function of this protein?
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
What are the official names of this protein?
UDP-glucuronosyltransferase 1-2, UDPGT 1-2, UGT1*2, UGT1-02, UGT1.2, B2, Bilirubin-specific UDPGT, UDP-glucuronosyltransferase 1A2, UGT1A2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: VIS_AGRVS
Sequence: MSKVAILGAGNLALTFAGDIARRLNEEVTAVIWAPTTNRRNFNEVRGIGTLELVGPDYEGAFTPQLEDDLEAAILDAEFIFLTVPTLAQEGILRELVKFDLSETVLIALPGSATSLTCKNILFPSHSPVAVIESTTSPYACRRIGERVHMLGVKACFEVAATSLLSNDLTSRFEALFPNRLQWYKDAASIFFSNTNPVVHPPGILVAKDAIENGMSPLPKFYREFVPAAIERVQELDNERLEIIAALGLESETGFTYSKKWYGGQATEWKEFFETYEGYAEVGTPTTMHHRYLTEDVKHIMVLWVQIAEVAGVQVPAMKSVIKEAGNVLYEDLFMTGRTLASMNLGGANPYRIVDALNGN
What are the official names of this protein?
Vitopine synthase.
What is the protein family that this protein belongs to?
Belongs to the lysopine/nopaline/octopine/opine/vitopine dehydrogenases family.
Protein: NA1D_BUNCN
Sequence: GVPCLCDSDGPSVRGNTLSGTVWVFGCPSGWHICTSDGPTIGSCCKK
What is the function of this protein?
Binds to the sodium channels Nav1. 1/SCN1A (EC(50)=453 nM), Nav1. 5/SCN5A (EC(50)=440 nM) and Nav1. 6/SCN8A (EC(50)=1740 nM), thereby delaying their inactivation (Ref. 1, PubMed:21802465).  Also inhibits Nav1. 2/SCN2A, Nav1. 3/SCN3A, and Nav1. 4/SCN4A, but to a lesser extent (PubMed:21802465).  Toxin effect on Nav1. 1 and Nav1. 6 (and on Nav1. 5, but in a lesser extent) consists in an incomplete inactivation (PubMed:21802465).
What are the official names of this protein?
Delta-actitoxin-Bcg1d, Delta-AITX-Bcg1d, Delta-AITX-Bcg1a, Delta-AITX-Bcg1b, Delta-actitoxin-Bcg1e, Delta-AITX-Bcg1e, Toxin Bcg 30.24.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: PBL20_ARATH
Sequence: MNCLFLFMSKKPKSRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPSPTSIKDLYTDREQNQNQNLRVFSFKELSDATCEFSRKLKIGEGGFGSVYKATINNPTVGDSHSSPLTVAVKKLNRQSLQGHKQWLAEVHFLGVVNHPNVVRLLGYCSEDRERLLVYELMSNRSLEDHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNVLLNEEFHPKLSDFGLAREGPEGDNTHVTTARVGTDGYAAPEYVITGHLKTHCDVYSFGVVLYEIITGRRTLERMKPLAEQKLLEWVKKYPINSKRFKMIVDSKLCNKYPIAMVRRVAKLADHCVNKIDKERPTMAFVVESLTNIIEESNSEDMGSSVGIRG
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL20, PBS1-like protein 20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MSHB_STANL
Sequence: MTDTLPPNRVVFVHAHPDDETIGTGATMAYYAADPDTHVTLVTCTLGEEGEIHVPELSQLAAAEADQLGGWRLHEWHMSCDALGVADRRMLGGPGAYRDSGMMDTPANKHPRAFWGADLTEAAAHLVAILRELRPQVLVTYDPNGFYGHPDHIQAHRVSVKAAELAADADFRPELGEAHKVSKFYWTTVPKSALATMFEEFSQSDDNPFEGVTSVDDLPFGVDDSEVTTVIQGKGFGEAKLASVRAHATQIPPDNWLAVMAAKVGVDATTTEHYILVDGKRGPADPETGWETDLFA
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: SLUR2_MACMU
Sequence: MQFHTGLLLAAVLSLQLAAAQALWCHQCTGFGGCSRGSRCPRDSTHCVTTATRVLSNIENLPLVTKMCHTGCPDIPSLGLGPYVSIACCQTSLCNHD
What is the function of this protein?
Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors.  May regulate keratinocytes proliferation, differentiation and apoptosis.  In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs, strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs.  Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.
What are the official names of this protein?
Secreted Ly-6/uPAR domain-containing protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: NIFK_KLEPN
Sequence: MSQTIDKINSCYPLFEQDEYQELFRNKRQLEEAHDAQRVQEVFAWTTTAEYEALNFRREALTVDPAKACQPLGAVLCSLGFANTLPYVHGSQGCVAYFRTYFNRHFKEPIACVSDSMTEDAAVFGGNNNMNLGLQNASALYKPEIIAVSTTCMAEVIGDDLQAFIANAKKDGFVDSSIAVPHAHTPSFIGSHVTGWDNMFEGFAKTFTADYQGQPGKLPKLNLVTGFETYLGNFRVLKRMMEQMAVPCSLLSDPSEVLDTPADGHYRMYSGGTTQQEMKEAPDAIDTLLLQPWQLLKSKKVVQEMWNQPATEVAIPLGLAATDELLMTVSQLSGKPIADALTLERGRLVDMMLDSHTWLHGKKFGLYGDPDFVMGLTRFLLELGCEPTVILSHNANKRWQKAMNKMLDASPYGRDSEVFINCDLWHFRSLMFTRQPDFMIGNSYGKFIQRDTLAKGKAFEVPLIRLGFPLFDRHHLHRQTTWGYEGAMNIVTTLVNAVLEKLDSDTSQLGKTDYSFDLVR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: ARNF_ECO45
Sequence: MGLMWGLFSVIIASAAQLSMGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.