PharMolix/UniProtQA huggingface dataset:
Protein: CADH8_RAT
Sequence: MPERLAETLLDLWTPLIILWITLPSFVYMAPMNQAHVLTTGSPLELSRQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNISIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEPYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-8.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PQQB_METEA
Sequence: MHVVILGSAAGGGVPQWNCRCSICSLAWAGDSRVRPRTQSSIAVSPDGERWLLLNASPDIRQQIQANPQMHPREGLRHSPIHAVLLTNGDVDHVAGLLTLREGQPFTLYATPGILASVSDNRVFDVMAADVVKRQTIALNETFEPVPGLSVTLFSVPGKVPLWLEDASMEIGAETETTVGTMIEAGGKRLAYIPGCARVTEDLKARIAGADALLFDGTVLEDDDMIRAGVGTKTGWRMGHIQMNGETGSIASLADIEIGRRVFVHINNTNPVLIEDSYERASVEARGWTVAHDGLTLDL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Coenzyme PQQ synthesis protein G, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: ST7_AOTNA
Sequence: MAEAGTGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TAL2_BACAN
Sequence: MKFFIDTANLEDIKKAYKLGVLAGVTTNPSLVAKEGIKFEDRIAEICQAVPKVESVSAEVTPDAVTAEEMIAQAEELIKINGGDEKVTIKLPMTLAGLEACRYLTEKGVKTNVTLIFTVNQALLAARAGATYVSPFLGRLDDISEDGVLLVAKIAELFDVHQLDTQIIAASVRHPDHVTRVAMAGAHIATIPYKVIEQLAMHPLTDQGIEKFAADWAKAPKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_STAA2
Sequence: MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: VF123_ASFM2
Sequence: MPSTGTLVIIFAIVLILCIMLLFFYKTVEAGKPSVLPPPIPPPTPPPSKKKYDHNEYMEKTDLEPEVKKNHRKWANEAEHLISSSVKGLENLDEAAFLANHKGHGFRTFEHAKSLFKEFLKKY
What are the official names of this protein?
Uncharacterized protein CP123L, pCP123L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP123L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: SPEB2_SCHPO
Sequence: MFTYQKIIQLALLLSGVCGALASIDTDSHLSPKVLEKLRPTENLAYEDDSLDDDTWRSKRWEFDYQYSGISTFAHLPHVRCLVEQSEDFDIAIIGVPFDTAVSHRPGARFGPKGIRSASSRQMAIRGFNPSLNVNPYESWAKILDCGDIPVSSYDNQLAVRQMTEGYIDLLSRKATASPASNNLKTAGLAKDGIFHPRLITLGGDHSIGLASLRALGHFYGNVSVIHFDSHLDTWNPKRYYPSYWHSDRADFTHGTMFWMASKEGLINNGTSIHAGLRTRLSGTDYYDYEEDNRVGFTFIEAQEIDEIGVNGIVERIKQVVGDTLVYLSIDIDVVDPGLAPGTGTPETGGWTTREMKSILRKLDGHLNLVGAEVVEVSPPYDDRAESTSLAASDFIFEILSSMVKHPLYDVKK
What are the official names of this protein?
Putative agmatinase 2, Agmatine ureohydrolase 2, AUH 2.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RAB2A_CANLF
Sequence: MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology.  Required for protein transport from the endoplasmic reticulum to the Golgi complex.  Regulates the compacted morphology of the Golgi.
What are the official names of this protein?
Ras-related protein Rab-2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (By similarity).
Protein: Y619_TREPA
Sequence: MRGCRVGQRTGTVGVRVFPVGLCALSLQARDCRGMCGKRLGKVMVLGCMLPGVAARVSLSPKLGVYGDARGGSDLWGICIQAPTMPDTENQAPPRYAPETPLVGLDVAFRAENGFLLQLTVDAALTRLMFCGRCLAGYSFRPGEGSTHLSVAAGFECTALIYDSQHFLSVLGQGLLQPSSSSYSAGNWHRPRSLLGVLTCTAKEVGAIHEESRIKGVCQNYAVPVQLGVQHYFGAHWGIDATATVSFGIDTKLAKFRIPYTLRVGPVFRT
What are the official names of this protein?
Uncharacterized protein TP_0619.
What is the protein family that this protein belongs to?
To T.pallidum TP_0127, TP_0315 and TP_0618.
Protein: RS2_HELAH
Sequence: MVTMKDLLECGVHFGHQTRRWNPKTKKFIFGVRKNIHIIDLQKTLRYFRYTYNIVRDASAQGKSIMFVGTKKQANETLKEFAESIQVPYVNYRWLGGMLTNFSTIRKSVRKLEIIEEMENSGQIDLLTKKEKLMILRKKEKLDKYLGGVRHMKKIPDMIFVIDVAKEKIAVAEARKLHIPIVAPLDTNCDPDLVDYPIPGNDDAIRSIRLFCKEMSEAILEGRELMQEEIVHADENSEEIEFVSNE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: TATB_NEIMF
Sequence: MFDFGLGELVFVGIIALIVLGPERLPEAARTAGRLIGRLQRFVGSVKQEFDTQIELEELRKAKQEFEAAAAQVRDSLKETGTDMQNSLHDISDGLKPWEKLPEQRTPADFGVDENGNPFPDAANTLSDGISDVMPSERSDTSAEILGDSGQTGSTAEPAETDQDRAWREYLTASAAAPVVQTVEVSYIDTAVETPVPHTTSLRKQAISRKRGLRPKHRAKPKLRVRKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RSMG_LEPBL
Sequence: MQDPEKFSIESIKERLKERFPKEMDEIIYFFDLELICKFTLFLKEKNEVGGFFSKRDSMEILDRHVLESIYHVYRITKKIGSWKGIQLGDAGTGPGIPGFFFRCLKAYPVVVLIDSQKRKLSHTESFVRSNRITDLKFQFIRTEESKLSLNYVVSRGFIPYPYSVEAVSNLIKIGGTYVPFLGKHDIDVKLEEKVLSYSGFRLESSEDLSSLEFLGMRHIKFLKKISSPRHGYPRTWKDISKESKSGNGKDRID
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAZ_ECOK1
Sequence: MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCREHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKAAALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: Y420_MYCPN
Sequence: MLKRQLLLAHRGYSDIAPENTQLAFELAFQYRFDGVELDVHLTKDGELVIIHDETTTRTALVDKTIELETLASLKQDDHSAFFKFKTQPQPIMTLKEFFDQYLDKFQLINVEIKTDQKEYPGIEAKIDALAQQYGKKVIEKVVFSSFNFASLQRLYDINPNYQIAFLFWTKKQFQAVDALKIKQVCQYLHPWTNIYEKFPDMVLSLQLPLGLWTLNSEVKFHQFRQDRMVYAQIANKKFEV
What are the official names of this protein?
Uncharacterized protein MG293 homolog.
What is the protein family that this protein belongs to?
To M.genitalium MG385.
Protein: PRMA_DEIGD
Sequence: MLVYHLPGTLDTREADLDLLWAAGATGLEERGGVIRAYFDTRTELPPQVSDGEWREEADQDWLAEFKRTLRPVRAGRVTIVPPWLREEVEAGQLPLVIEPGMAFGTGHHATTRLAVEALSALNLATLGPRGTGARVLDVGTGSGVLAIAAALLGAGFALGVDIDPITIPIARENAQINGIPASRVRFAEGTLGADPLTFPDEGVDTYDVVVANLYAELHDLLAGEYAAHLVPGGALILTGILTVKLPLVHAALDREGFTNVQETLDGEWALVTARAPLG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_RHOE4
Sequence: MSLVLLPAVDVVNGEAVRLVQGEAGSETGYGSPRDAALAWQNDGAEWVHLVDLDAAFGRGSNSELLAGVIGDLTVKVELSGGIRDDASLEAALATGCARVNLGTAAIEDPEWCARALAKYGDKIAVGLDVRLVDGQYRTRGRGWVTDGGDLWETLARLDRDGCTRYVVTDVSKDGTLTGPNLELLSQVCAVTDAHVVASGGVSTIEDLLAISSLVDQGVEGAIVGKALYAGRFTLPEALAAVSG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_BUCCC
Sequence: MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFKKILYKICSNNPPKIIINIEKKKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQLAYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKFLIKNKKKKVIYIHSENFIQNMVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTADCYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKIFSNVRELEGILKKIQILSILNKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIRISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFGKKDHTTVLYAYKKINQLKKKKTEIYSDFIYLFNQLNA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEA_SALPK
Sequence: MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PA2A1_TROCA
Sequence: MYPAHLLVLLAVCVSLLGAASIPARPLNLYQFGNMIQCANHGRRPTRHYMDYGCYCGKGGSGTPVDELDRCCQTHDDCYGEAEKLPACNYMMSGPYYNTYSYECNDGELTCKDNNDECKAFICNCDRTAAICFARTPYNDANWNIDTKTRC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 1, svPLA2, Phosphatidylcholine 2-acylhydrolase 1, PLA-1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL9_ACAM1
Sequence: MGKRVQLVLNEDVRKLGYSGDLVEVAPGYARNYLIPKGIAYRATPGVLKQIEHRKAEELKRLEGIKDEAAKQKVALQTIGTFRIEQKAGEEDMLFGRVTSPDVAELIANISGFEIDKRGIDIPDIRKLGTYSVDIKLHPEVIATVKVEVVPE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SPEE_SALG2
Sequence: MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA2_PSEPK
Sequence: MRVLVLGSGVIGTASAYYLARQGFEVTVVDRQPAVAMETSFANAGQISPGYASPWAAPGVPLKAIKWLLERHAPLAIKLTGDVDQYLWMAQMLRNCTASRYAVNKERMVRLSEYSRDCLDELRAETGINYENRSLGTTQLFRTQAQVDAAAKDIAVLEQSGVPYELLDRDGIARVEPALAGVKDILAGALRLPNDQTGDCQLFTTKLADMALKLGVEFRFGQDIQRLDFAGDRINGVWIDGKLETADRYVLALGSYSPQMLKPLGIKAPVYPLKGYSLTVPITNSDMAPTSTILDETYKVAITRFDNRIRVGGMAEIAGFDLSLNPRRRETLEMIVNDLYPRGGDLSQASFWTGLRPATPDGTPIVGATAFRNLFLNTGHGTLGWTMACGSGRLLADLIARKKPQISAEGLDISRYGNSREVAKHGQSAPAHQQ
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: RPOC2_CARPA
Sequence: MAERANLVFHNKVIDGTAIKRLISRLIDRFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRVTDPFNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPKNRTMPERIFIQTLIGRVLADDIYMGPRCIAIRNQDIGIGLVNRFITFRTQSISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRSPSNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVVIESEDIIHNVTIPPKSFLLVQNDQYVESEQVIAEIRAGTYTLNYKERVRKHIYSNSEGEMHWSTDVYHAPEFTYSNVHLLPKTSHLWILSGGSSRSSLVPFSLHKDQDQMNIHSLSVEQESISSLAVNNDQGRHKFFSSNFSDKKKCGIPDYSEFHRILDTGHCNLIYFASLHENSDLLAKRRRNRFIIPFQSIQEQEKELMPRSGISIEIPINGIFRRNSILAFFDDPRYRRKSSGILKYGTIGAHSIVKKEDVIEYRGVKKFKTKYQMKVDRFFFIPEEVHILPESSSIMVRNNSIIGVDTRITLNIRSQVGGLVRVERKKKSIELQIFSGDIHFPGKTDKISRHSGILIPPGRGKTNSKESKKLKNWIYVQRITPTKKKYFVLVRPVATYEIADGINLATLFPQDLFREKDNMQLRVVNYILYGNGKPVRGIFDTSIQLVRTCLVLNWDQDNKSSSVEEVRTFFVEVSTNSLIRDFLRIDLVKSQSHISYIRKRNDPSGSGLISDNGSDRINPFYYKERIQQSLSKNHGTIRTLLNRNKECQSLIILSSSNCFQMGPFNHVKYHNVIKQSIKKDPLIPIRNSLGPVGTAIQIANFYSIYHLITHNQISVTKYFQLDNLNQIFEVIKYYLMDETGRVYNPDPCSNIILNPFNLNWYFLYQNYHHNYCEETSTIISLGQFICENVCLAKNGPHLKSGQVLIVQVDSVVIRSAKPYLATPGATVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISLNLEKRVEGWNKRITRILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAICYRAILLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPAGTGFKGLVHCSRQHTSILLETKKKNLYLFEGEMRDIFFHHRELFDSCISKNLHNTSERSFIGLNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RHAA_LISMC
Sequence: MGQETEISKRYQVAKERYQAIGVDTEKALKTLKDIKISMHCWQGDDVKGFLNPDGELTGGIMATGNYPGAAHTPKQLRQDLEKAYSLIPGKHKLNLHAIYVDTDEKVDLNEIEPKHFTPWVEWAKEQGLGLDFNPTFFSHPMFKDNYTLASPDKEVRDFWIEHGKRSRKISEYFGKELGQTSINNFWVPDGIKDCPIDRYTPRKRLMEALDEVFAEKLDEKYTQEAVESKLFGLGAEAYTVGSHEFYMGYGITRDKLICLDAGHFHPTEVISNKLSSLALFSKGVMLHVSRPVRWDSDHVVIMDDELIEIGRELVRNDLLGITNIGLDFFDATINRIAAWVVGTRNTQKSLLKALLEPTADLKKMELENDFTSRMAITEELKDFPFGDVWNYFCEINGVPVGLDWLKEVKAYEEDVLLKR
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_HV1ZH
Sequence: PYPPPEGTRQARKNRRRRWRARQRQIHSLGERILTTCLGRPTEPVPFLLPPIERLRIDCSEDRGDSDPQGVGDSQIPGKSCDLLGSGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm (By similarity).
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: Y3471_BRADU
Sequence: MDTVRWIISTAPEIFLLLAVAIGTMLGRLKIHGFAIGTTACILIVSVLIGQLGTFTFPALLRIVLFSLFVFTIGYKSGPEFFASLSVRTLAQVAMALVLGGTGLVIVLAFAFALKLDPGTASGLAAGALTQSSVIGTASGALAQLGLPKTVLEQQEANIAAGYAVTYVLGYILTLLYVPFAAPKLMGVNLKDEAKKLEVELSGGAPPKTENLSYRKFQARAYRVTAAAGRTVKAIEEDIGSRTVIERIVRQGADIEPRLDTVLEAGDDIVIAGRTAAIVAAKPIIGTEIDADEILKAIPGNVLDVLVDNRNLHGRSIRDVADRIGGDARGVFLRALTRHGREAPLSADTRVYVGDVMTLVGSTRNIERAAKQVGQIVRSGDRTDIAFLAAGIAAGLLAGLVSFKVGGIALTLGGGGGALIAGLLCGWLRSRRPTMGAMPPAAQQTLSDLGLGGFIAAIGLANGHAAWVAIQAHGLLLVGMGLVVTLVPLVVATLFAYHVLRMNPVITCGALAGAMTVDAAVTGACEIAESQTPVLGVAVPYAVGNVVLTVLGPIIVACTFVG
What are the official names of this protein?
Uncharacterized transporter bll3471.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECB_SHEWM
Sequence: MAEVANNEQQDPQFNIQRVYTKDISFETPNSPAVFQKEWTPEVKLDLDTRSAKLADNVFEVVLSLTVTAKNGEETAFLCEVQQAGIFAINGLTEQQLAHSLGAYCPNILFPYAREAVGSLVARGTFPQLNLAPVNFDALFAQYVNQRQAGAEEAAAKTEEASA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_SINFN
Sequence: MSHSVSLTFPDGSVREFAAGTTGRDVAESISKSLAKKAVAIALDGELRDLSDPIADGKIEIVTREDKRALELIRHDAAHVMAEAVQELWPGTQVTIGPVIDNGFYYDFAKNEPFTPDDLPVIEKKMKEIIARNNPFSKEVWSRDKAKEVFAAKGESYKVELVDAIPEGQDLKIYYQGDWFDLCRGPHMASTGQIGTAFKLMKVAGAYWRGDSNNPMLTRIYGTAWHTQEELDQYLHVLAEAEKRDHRRLGREMDLFHFQEEGPGVVFWHGKGWRVFQSLVAYMRRRLEVDYQEVNAPQVLDKSLWETSGHWGWYRDNMFKVTVAGDETDDDRVFALKPMNCPGHIQIFKHGLKSYRELPVRMAEFGAVHRYEPSGALHGLMRVRGFTQDDAHIFCTDEQMAAECLKINDLILSVYEDFGFKEIVVKLSTRPDKRVGSDALWDRAEAVMTDVLNTIEAQSEGRIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIDKDSEKRQPVMIHRAICGSMERFLGILLENYAGHMPLWISPLQVVVATITSDADDYGREVAARLREAGLTVETDFRNEKINYKIREHSVTKVPVIVVCGKREAEERSVNIRRLGSQAQTAMSLEEAVAALSSEAMAPDLKRKMERSARAA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.