PharMolix/UniProtQA huggingface dataset:
Protein: FPG_RHORT
Sequence: MPELPEVETVRLGLTPALVGERLSRVAARRPALRLPIPVDLVQRLTGKVVGSLDRRAKYLLLRMIDGPVALIHLGMSGSMTVGPLAGHAEPGPHDHILFETEAGLRVTFRDPRRFGLITLAEPETLDDHPLLAKLGPEPLSEAFDAEVLVRRLNGRQAPIKAALLDQGVVAGLGNIYVSEALFRAGISPLRPAASVTGAWAEALVAAIRAVLGEAIAAGGSSLRDHRQTDGALGYFQHRFAVYDRVGQPCPGCDCDVARTGGIERMVQSGRSTFFCGRRQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MURG_TOLAT
Sequence: MSRTMVIMAGGTGGHVFPGLAVAHRLQADGWNIHWLGTPDRMEADLVPAHGFPIEFINIRGLRNHGLVRKLLAPFQICKAVLQAFMILRRIRPDVVLGMGGYAAGPGGVAAKLLGIPVVLHEQNAAAGLTNRLLAKIATRILMGFEGAFPLTERSRVVGNPVRDEFLQLAQKPLKKYHTGNPLKILIVGGSLGARPLNQIVPHALAKLNNIDVRHQSGKGNASAVSDLYQSLGVTTVTVTEFITDMAAAYEWADLLICRAGALTVAEVAAAGIPAVFVPLPHAVDDHQTRNAESLTRRGAAVLMPQKEMTADKLAELIAQWQVDPRQLQKIAQLSRAAAILDATDRVVSECKALI
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: S72L6_HUMAN
Sequence: MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATTYKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKAGKSFLHTVCFY
What is the function of this protein?
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II.  Plays a role in RNA processing and termination.
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6, RNA polymerase II subunit A C-terminal domain phosphatase SSU72L6, CTD phosphatase SSU72L6.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
Protein: Y922_ENTFA
Sequence: MKNSENDYIQSLFQILPGLLTAFLVACLSKFLAIWLPSLGAATIAILLGIFLGNTFVRGANLNRGTKVAESKLLEFSVVLLGTTVTFQTIAQIGLQGVAFILIQMSLTIIFAYLIGKKLAFSDNMSLLMAGGNAVCGSSAIASIAPAIQADEEEKGQIITLVNLLGTVLMLTLPILSGILYGTNLLARSALIGGTLQSVGQVVASANMVNENAVQLAMLFKIMRIVLLVAVVYLFGRFKQSKTAESEAELVEVTKKSSALPWYVVGFFIACVFNSLIHFPVVISETAHFFSSWFEITALAAIGLRLDFKKFFQEGKRFLIYGLSVGTVQVVLAILLLALLQF
What are the official names of this protein?
UPF0324 membrane protein EF_0922.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOB_EHRRG
Sequence: MINKHNSVLHNQFWQSYNHRGFMVTKLSDLMSYVSSWARSNSLWPMTFGLACCAVEMMHTAASKYDLDRYGIMFRASPRQADVMIVAGTLTNKMAPALRKVYDQMTEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILCLQQKINRTATST
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SORT_PENRW
Sequence: MSHTEPKAPVNTGEVENGHLYDGSGTEDDPFIVEFQKDDPGNPMNWGQSRKWFIAAIATLSVFAVTFTSSAYSVSANEVFKDFDISTEVFIVGLSLFVLGFAIGPAVWANIGLRSELYGRQILWIITHIAMVAFLGGSAGSQNVATLLILRFFAGTFGGSPLVNSGGTIADLFPPAQRGLALTIYCVAPFLGPILGPIVGGFVSESVGWRWVQGVCVIFIGVVGILGIVFIPETYGPVLLQRRTHQLAKADGKIYVSVLEKNQGKKLPSEVFKRALFRPWIFLFLEPIVLIASVYMAIIYGTVYMFMGAMPIVYNEDRGWSVGIGGLAFLGIAVGIIFGLVYAIWDNNVRYMKLFAAKSANPESRLPPAIVGGVALPIGMFAFAWTNYPSIHWSVSIILSAPFGFGCVLVILPIMNYLIDTYTIYAASVLAAAAIFRSVVGAVFPLFTTQMYHNLGIHWASSIPAFLTLLCMPFPLIMYRYGEAVRMKCKYSFEAAEMMRKMQLQQTAAATTTEKDKDSSSE
What is the function of this protein?
Major facilitator-type transporter; part of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria (PubMed:29104566).
What are the official names of this protein?
Major facilitator-type transporter sorT, Sorbicillinoid biosynthetic cluster transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENO_DESVH
Sequence: MSTIVSVWAREILDSRGNPTIEVEVSLESGHSGRAAVPSGASTGTREALELRDGDKGRYKGKGVEKAVDNVMGEIAEAVIGLDALRQVQLDNTLLDLDGTDNKERLGANAMLGVSLATARAASSFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALRMGAETFHTLKALLAADGHVTSVGDEGGFAPNLKSHDEAFKYITRAIEESGYIPGAEIALAIDAAASEFYRDGKYHLAGEGKTFSNSEMTEWLGEFTAKYPLISIEDGLAEGDWEGWGELTYKLGDTVQLVGDDIFVTNPDILAQGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYTTVISHRSGETEDHFIADLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDAGIYFGPMIASHFGYEGDEEFEDA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EIF3E_YARLI
Sequence: MEYDLTQKTLPFLDRHLIYPLLQFLKGRGVYNDTELLQLEYDLLKDTNMTDYLVELSKELGQNDADLQAKKENVVKTLAELEEATKPVFEVLENPEVVSELKENKTQNQALLTSKYGLSVEQINLLYKFGQFQYNAGRYQAASDILYHFRALSTDPELVASATWGRFACEILTSQWDSVLEELGKLRDSVDSRSLDPQQQLHQRMWVIHWSLFPFFQNDTKGKDALCDLFFSSSYISTIQAACPWILRYLVVAVIAGGHPHTASVFQKRLKDLVRVVGQEEYEYQDPLTRFVKSLYIDYSFEDAQNQLADCEKVLKQDFFLADSADAFLESARKLMSQVYCRVHQRVDIAQLSQTLNLSQEQGEKWIANLIKDSRMDAKIDESDSTVILNHPSVSVYQQVIEKTKGLTFRSSQVLNQGVTI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIR2_CANAL
Sequence: MTTFWSQTINRQNGGVATATATATATAATTTPTAGGTGAGTTTSTKGMITPTPFNIDINNDLNDFDGKFIETFKPDLELQKKYRSFIQREGALSFLRTEITQSMSKRDICVLILNLGYPKKAVEDYPILTLKELAYILLKLMLTDSAQLEPKVEIDENDNKNDGTNNSDIDSDIDSNSDMDSQSESGELDDAMDVDDSLSENEDEYDQDMSTTTLKRTINMTPFKYKLPDLISDLSRAKKIMVVTGAGISTSLGIPDFRSFKGLYNQLSKLNLSDPQKVFDLQTFMREPGLFYTIAHLVLPPDGKFSLLHAFLKLLQDKHKLLRNYTQNIDNLEQRAGLKSEKLVQCHGSFAKAKCVSCQGIFAGEKIYNHIRRKQVPRCAICWKNTKQAPIHFGAIKPTITFFGEDLPERFHTLMDKDLQQIDLFLVIGTSLKVEPVASIIERVPYKVPKILINKDPIPNRGFNLQLLGLCDDVVSYLCKCLKWDIPHADFNNNDEFKLSKLKNGDWEIVKKSTSTKK
What is the function of this protein?
NAD-dependent deacetylase.  Heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and that also suppresses recombination in the rDNA and extends replicative life span.  It acts as a NAD-dependent histone deacetylase, which deacetylates 'Lys-9' and 'Lys-14' of Histone H3 and 'Lys-16' of Histone H4.  Functions in the distribution of oxidatively damaged proteins during cell division.  Mediates phenotypic switching.
What are the official names of this protein?
NAD-dependent histone deacetylase SIR2, Regulatory protein SIR2, Silent information regulator 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUTC_SALHS
Sequence: MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSFGVLRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVARVLTSGQKADAAQGLSIIMELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGASVAEMKGIIVRHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAM_SALNS
Sequence: MIRKAFVMQVNADAHEEYQRRHNPIWPELEAVLKSHGAHHYAIYLDQERNLLFATVEIESEERWNAVASTDVCQRWWKHMRDVMPANPDNSPASAELKEVFYLQ
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_RHILO
Sequence: MSADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLKAGLEKGGIQPTVITMPPGEKTKSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFSAGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLVGVFLQPKLVLADTEVLDTLPIREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEFETGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARVETHLRAVGLPWRMADIPGELPDAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPASEVLSFLRENHPTSRKAG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO13_ADEG1
Sequence: MTTTPCALSYARTKECSVPARGPPHAMLVTHHMTYNSLPQCTKRRRESQSSLSSEEEQIASCIPDTPSPCLFPSTSPMDQLVERLFVEGVAHEVQWNFPSKNLIPTYERERVLEALKERFGPGQSLINQLPSEEPDTLKAAFYNVCDNWFHQMMEAEGYEGKVAANAILRWLRGELNTLVLCGGRLSNAKSLFNALCACFPLAISDSRINSILSLGEIAPHASLYCLPFVDEKPDPLMLHFMEGNAATCRLNKKTFHIPSTPMLIHCADLSLANEFTARNTVVFFLTGDHTKTPPCYHPRKELRDFVANAAACACLMTLHCKRDNKLCNPCIRTPLQNQ
What are the official names of this protein?
Uncharacterized protein ORF13.
Protein: RL23_XANOR
Sequence: MSSNEKIFSVLRAPRVSEKTARLQEISNQYVFEVSNEATKADVKAAVEQLFDVKVKAVNVVNVKGKSKSFRNRAGNRGNWRKAYVRLVDGQSIDVTAKA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PDRP_BRUSU
Sequence: MTRPLSYFHLHLISDATGETLLAAGRAAAAQYANARAIEHIYPLIRTEKQLRKVLEGIDAEPGIVLYTVVDQKLAAIIDESCADMGVPSVSVLEPVLNTFQSYLGAPAHRRASAQHVLNADYFRRIDALNFMMEHDDGQLPLDIEEADVIIVGISRTSKTPTSIYLANRGIKAANVPLVLGIPVPEILFAAKRPLIVGLVATAERISQIRQNRPLGNIPSLDTGLYTDRVSISEELAYARNLCNRHGWPIIDVSRRSIEETAAAILALLRNGKKEGSSS
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: GLGA_NATTJ
Sequence: MKVLVATAEASPFAKRGGLGDVLGALPIAIKKQSEIDIRVVLPGYSAIPSQFKSEFQPIDSIIIPLGWRAQKSRVSSYNFRNVTFYFIENDYYFNREDIYGYFDEAEQFGFFSKAILDIMPLLDFYPDIIHLNDWHTAMVSPLLKYKYAHKTNYNQMKTILTIHNLKYQGIFTPHVLEDFFDLHDHKLQHDPEYLEYHGQISFLKGGLIFSDAITTVSPTYAKEIQSPELGMGVDGLLHKRRDDLYGILNGIDYQDYNPKTDVNIYRNYNLPDEGKTNEKLINKLRLQEDLRLPVSSRVPLIAFINRLVKQKGLDLITYVLPELLESEEVQFVFLGTGDPHYEQYLSYLAEKHQNLSAQIKFDEGLARKIYAASDLFLMPSLFEPCGIGQQIAIRYGSVPIVRKVGGLHDTVYPSISEEGTRGIGFTFESFNAHEMLFTIKEAIQYYHQKAFWQEIINNLTTIDFSWEKSACEYIELYHKLIHRNTNSTRKESYLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RK14_CYAPA
Sequence: MIQPQSYLTAADNSGARKLMCIRVLGGGNRRYARIGDVIVAVVKDGIPNIPIKKSDTVKAVIVRTRKELKRDNGMNICFDDNAAVIINADGNPRGTRVFGPVARELRDKNFTKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, cyanelle.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: TUBR_CBCP
Sequence: MAVNKNEYKILIMLKENQCTTELKSFTYTKLCNISKLSMSTVRRSIKKFLELQYVKEGCKQGISKTFYITPNGIEKLKSIM
What is the function of this protein?
A DNA-binding protein that is part of the type III partition system presumably used to ensure correct segregation of this bacteriophage.  Binds to tubC (centromere-like site) DNA upstream of its own gene in a sequence-specific fashion (consensus TTGAC); binds to multiple sites in the tubC region, probably spreading from an initial site (PubMed:22538818, PubMed:29762781).  Upon binding to tubC forms flexible loops over about 1 kb of DNA that forms 2 rings, covering tubC and the promoter region.  This probably shuts off transcription of the operon.  DNA is both bent and untwisted by TubR (PubMed:29762781).  The TubR-tubC DNA complex binds to TubZ forming large bundles and decreasing TubZ's GTPase activity (PubMed:22538818).
What are the official names of this protein?
DNA-binding protein TubR, Centromere-binding protein, CBP.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SYR_LEGPH
Sequence: MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPVDPSVEKIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGGDKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: API5_ORYSJ
Sequence: MAASDADAAEVERLYELGERLSSAKDKSQHAADYEAIISAVKGQSVKAKQLAAQLIPRFFRSFPALAPRAMEAMFDLVDMEELATRIQAIRGFPLLAKDAEFVSKIADILGQLLASEENVERDAVHKALMSLIRQDVKSSLQPLFKHVESGSEIREKVICFLKDKVFPVKAELLKPQAEMERYITDLIKKSVLDVTGLEFKLFMDFLRSLSIFGDSAPRESFQELIEIIQAQADLDAQFNVSDIDHIERWTSCMYMALPIFMRGGSSSKFLNYFVKQIVPVFDKIPEEKKLDLLKTVAASSPYATAQDARQLLPPVVQLLKKYMPGKKVEDINHNYVECLMYIFHHLAHKTPNTTNSLCGYKIVTGQPSDRLGEDFSEHYKDFTERLTGTEETVRAVSKRLTQGMADFNKAISSAKTEEEKTKIKSDQQKSTMTMRAYNNILAMAQPLRAKSPLFIGDKKITLSWMEQPKKPAPTTTGGKRSQPATNGNTPASKKGRGEGAARNQLVNRAFEGLSRGGRGSGRGRGRGGRGRGWGYR
What is the function of this protein?
Putative anti-apoptotic factor involved in the regulation of tapetal programmed cell death (PCD) and degeneration during anther development.  Interacts directly with the DEAD-box ATP-dependent RNA helicases AIP1 and AIP2 that form dimers and bind the promoter region of the cysteine protease CP1 involved in tapetum PCD.
What are the official names of this protein?
Apoptosis inhibitor 5-like protein API5, Protein APOPTOSIS INHIBITOR 5.
What is the protein family that this protein belongs to?
Belongs to the API5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL6_STRPD
Sequence: MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIKVEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SOSB1_RAT
Sequence: MTTETFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYNTQQASNKSVQNDSSPTAPQATTGPPAASPASESQNGNGLSTQPGPVGGPHPSHAPSHPPSTRITRSQPNHTPSGPPGPSSSPVSNGKETRRSSKR
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines.  The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).
What are the official names of this protein?
SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOSS-B family. SOSS-B1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment (By similarity).
Protein: AEGP_MOUSE
Sequence: MCLPSHLLSTWVLFMAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDETQCGFHGASTIPSTSFTCNFEQDSCGWQDISTSGYRWLRDRAGAVLHGPGPHSDHTHGTDLGWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIASRDVAELRLDLTHGVETLTLWQTSGPWGPGWQELAVNTGRIQGDFKVTFSATRNATHRGAVALDDVEFRDCGLPIPQARCPLGHHHCQNKACVEPHQLCDGEDNCGDRSDEDPLICSHHMATDFETGLGPWNQLEGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLISVAKPGTTAVLYSPEFQGSVSNNCSFTFYYYLHGSEASHFQLFLQAQGLNTPQVPVLLRSRHGELGTAWVRDRVDIQSAHPFRILLAGETGPGGVVGLDDLIMSSHCMLVPAMSTLQSSLSGPVPLALYPQTSIKLPQQTCEPGHLSCGDLCVPPEQLCDFQKHCAEGEDEHKCGTTDFESASAGGWEDISVGKLQWQWVEAQEKSKPAGDANRDAPGHFLSLQKAWGQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVENGFRELLWQAPGGGSGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRDCNPMVTTESDQELSCNFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQGFFMFLDPTDPPARGQGALLLTRPQVPVVPKECLSFWYRLYGPQIGTLCLAMRREREEDILLWSRSGTHGNRWHQAWVTLHHQPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTHQSNASGLASWGPWIDHTTGTAQGHYMVVDTSPNVLPKGHVAALTSEEHQPLSQPACLTFWYHMSVPNPGTLRVHVEESTRRQELSISAHGRSAWRLGSVNVQAEQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGSCDFETGLCGWSHLPWPSLGGYSWDWSSGATPSRYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATTVSCLRFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWLQVQIELSNSEEFQIVFEATLGGQPALGPIAIDDVQYLAGQQCKQPSPSQGEVAAPVSVPVAVGGALLFFMFLVLMGLGGWHWLQKQHCPGQRSTDAAASGFANILFNADHVTLPESITSNPQSPPDLA
What is the function of this protein?
Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia.
What are the official names of this protein?
Apical endosomal glycoprotein, MAM domain-containing protein 4.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NANM_SHISS
Sequence: MNKTIMALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIGLGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSLAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAGGFAGISNDSLIFAGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RV161_YEAST
Sequence: MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRAVTASQTTIAEVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKDASKLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK
What is the function of this protein?
Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level.
What are the official names of this protein?
Reduced viability upon starvation protein 161.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SELO_CUPMC
Sequence: MCTHTGHSAAPSLSGLIDAEPCHFWLPLMPNEPTDVLPPTSFNVPFGTRPGIAALGERFFTRLSPTPLPSPYLVSVAPAAAALLGWNETDLQDAVKDPAFIDSFVGNAVPDWADPLATVYSGHQFGVWAGQLGDGRAIRLAEAQTPGGPWEIQLKGGGLTPYSRMADGRAVLRSSIREYLCSEAMYALGVPTTRALSIIGSDAPVRRETIETSAVVTRLAPSFIRFGHFEHFAAREDHASLRQLADFVIDNFYPACRNAANPYQALLRDVSLLTADMVAHWQAVGFCHGVMNTDNMSILGLTIDYGPFGFLDAFDANHICNHSDQQGRYAYSQQPQVAFWNLHCLAQALLPLWRDANAADPEAEKAAAVEAAREALDPFRDRYAEAFFRHYRAKLGLRSEQEQDETLMTNLFRVLHENRVDYTSFWRNLSRVSSLDNSHDAAVRDLFLDRAAWDAWAAEYRARLQSEQSDDAARTTAMLATNPKYVLRNHMAETAIRAARDKDFSEVDRLMAVLSKPFDEQPEAESYAKLPPDWASGLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: S100_LEPPA
Sequence: SADEQKLRERFEALDKDKSGTLSVDELYEGVHAVHPKVSRNDIVKIIEKVDTNKDGQVSWQEFIEAFKRLADLKL
What is the function of this protein?
Binds both calcium and copper, but not zinc.  May be involved in calcium signal transduction.
What are the official names of this protein?
Calhepatin.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.