PharMolix/UniProtQA huggingface dataset:
Protein: RRP42_YEAST
Sequence: MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSECIVSIKSKVVDHHVENELLQVDVDIAGQRDDALVVETITSLLNKVLKSGSGVDSSKLQLTKKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFDDLEVEELPTFHDYDMVKLDINPPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKITSPIRSVALNDSNVKSFKPHLLKQGLAMVEKYAPDVVRSLENL
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  RRP42 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation.
What are the official names of this protein?
Exosome complex component RRP42, Ribosomal RNA-processing protein 42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: RL23_LISMH
Sequence: MDARDIIKRPVVTEESTSILDDKKYTFEVDTRATKTQVKYAIEEIFDVKVAKVNVMNYKGKLKRMGRYAGYTNKRRKAIVTVTADSKEIQFFEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SCPA_DESHD
Sequence: MSNGSSVSHSANTAPYVELPAFQGPMDLLLHLIQQEKVDIYDIPIARITDQFIQVVRQMEDLDMEVTTEFLVLAAQLLQIKSRYLLPKPVKDVTVEEEGDPRQELVERLLAYRAFKQAAETLGEIQISSGQRYFREVDVDGLRSQFTPADPLAGIHFEALWHAFQRIIERAEQGEEIRTVEPDEIPIEVMVNDVLRRVILHPRGLRFSQLIRGTKRMEIIVSFLALLELLKSGKVHCEQSSQNEEIFVFPTEKAWEFTEGE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PTH_CLOBM
Sequence: MYLVVGLGNIGKEYKKTRHNIGFDVVDIVAEKYNIEINRQKFKGSYGEGRIGNEKIILLKPSTYMNLSGESVIEAANFYKIDKENIIVIYDDMSIDIGKLRVRGKGSAGGHNGIKNIIQHLNSDIFPRVRVGIGQPDENVVNYVLGKFSKDQREVIEKVLAMSAKACISIVEDGVTEAMNKYNGVKIEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_LACPL
Sequence: MSDITAAQTTLQQAQHIVFMTGAGVSTPSGIPDYRSKNGLYTEHHNAEYYLSHAFLAEHPLEFYQYLQSNLYYPDAQPNVIHQKMAALTQQGRASVITQNIDNLYGVAKTAQLVEFHGNLYQVYCTKCGQHVDWHEYLKSPYHQTDHGYLRPNVVLYDEGIASANIERAVQYLQQADLVVICGTSFRVYPFAGLIDYRNPKAQVLAINAEPLQLPFAFTMVQQDAVDFFEGVQV
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMO1_ASPNG
Sequence: MLPHPLAILSEEETNIARNVILAQHPNTVIDFREIYLSEPPKAQLLEFLALEHSGRLSPTSPRPPRLALCQYDVIGNDRIPSFEESVVDVGTRQRVQHRVVGKEHHASLTLSEFDTLVERCFASPLFQKALADFDLPEGFEVVIEPWPYGGLDYVEEKRRYFQGLCFATDKRKNNPDANFYSYPLPLIPVMDALTQEIIRVDRPATGGKGEGLTEQTFKRDIIGHCKDSDYVPELNPGGTRKDLKPLNVVQPEGPSFRITEESLVEWQKWRFRVAFNPREGATIHDVWYDGRSVLYRLSVSEMTVPYADPRPPFHRKQAFDFGDGGGGNMANNLSIGCDCLGVIKYFDAVMTGADGSAKKMPNAICLHEQDNGIGWKHSNWRTGRAVVTRHRELVVQFIITLANYEYIFAYKFDQSGGITVESRATGILNVVNIDAGKVSEYGNVVSGGVLAQNHQHIFCVRIDPAIDGPNNSVQVEESHPVPMNAVTNPNGNFYKVNTETMERAGFFDAAPELNRTVKMVNPHKKNPISQKPVGYKFIPLATQRLLADPNSIQARRAQFAQHHVWVTKYRDGELYAGGRYTLQSQEEIEGVSDAVKRGDSVVDTDVVVWSTFGITHNPRVEDWPVMPVEIFQLMIRPADFFTANPSLDVPSDKNISSRVVGNDCCRNAHI
What are the official names of this protein?
Copper amine oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
Protein: RNY_STAS1
Sequence: MNLLGLLLILLGIILGVVVGYIVARNLLHQKQLQAGQTAEDIIEQGNKEAENIKKEKLLEAKEENQIIKEQSEIELRERRGDLQKQEARLLQKEENLERKSDLLDKKDEILEQKESKLEERQQQVDAKESSVQTLINKHEQELERISGLTQAEAAQEQLQRVEDELSQDIAILVKEKEREAKEAVDKNAKELLATTVQRLAAEHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVDKARKEVDDIIRDAGEQATFEINVHNMHPDLVKILGRLQYRTSYGQNVLKHSIEVAHLSGMLAAELGEDITLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYAENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYEGVEKAFAIQAGREIRVIVSPDTIDDLKSHRLARDIKSQIEDELQYPGHIKVTVVRETRAIEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ATPD_STAS1
Sequence: MANIAKKYAKALFDTAKDADILDDMYDEFSTINEAVQSENKKLQALDADPQKDVEQRRRFVSIVFGQTNQYLQNMLTILASNRHLGHIHEIYIAFETLYNEEHNQDYAVIESVYQLSEEELSSIEEIIKARTKLSKIMITNKINPELIGGIRVKVGTKVMDASIKNDLAQLERQFIRVK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YCFP_ECOSE
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: FIXA_SALPB
Sequence: MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVERELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVAAPKQRERQRVVIEGDGEEQIAAFVENLRKII
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: SYP_STRGG
Sequence: MAQVQRMSRLMVKTLRDDPADAETLSHKLLVRAGYVRRNAAGIWSWLPLGKKVLDNISNVVREEMDAIGAQEVLLPALLPKEPYEASGRWEEYGDLLFRLKDRKGGDYLLGPTHEEIFTQTVKDQCTSYKDLPVMLYQIQTKYRDEARPRSGVLRGREFQMKDSYSFDTTDEGLAHSYALHRAAYIKIFERLGLDHRIVSAVSGAMGGSASEEFLAPAAAGEDTFADCPNCDYAANTEAVTFALAPVDGSAHGAVEELDTPDTPTIETLAAHLGVPASATLKNLLVKVDGEIVAVGVPGHREVDLGKLGEHLAPAVVELVTAEDFVGRDDLVRGYVGPQGLEKVRYLADPRVAPGTSWITGANKEGKHARNVVAGRDFEVDEYLDVVVVEEGDPCPKCGTGLVLDRAIEIGHIFQLGRKYADTFQLDVLGQQGKPVRVTMGSYGIGVSRAVAALTEQTADDKGLCWPREIAPADVHVVAAGKALQTELALDVSEKLNAAGLRVLVDDRPGVSPGVKFTDSELIGVPKILVAGRRSADGVLELKDRRTGEREELTVDEAIARLTADLA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_SHESW
Sequence: MARRPKGRFIDGIVLLDKSTGMSSNFALQRVKRFFNANKAGHTGALDPLATGMLPVCLGEATKFSQHLLDADKRYLVTAKLGERTDTSDSDGEVVQTRPVTFTEAQLLSALEHFRGDTQQVPSMYSALKYQGQPLYKYAREGIEVPRESRPITVFELNFISLEGDELTLDIHCSKGTYIRTIIDDLGEMLGCGAHVIMLRRTQVAQYPYAKMVTLEQLEALVTQAHEQQIDPSVLLDPLLLPMDTAVADFPEVNVPEASAAYLMQGQAVRVTGLKADTLVRITLGDAHRFVGIGAMNDDGLLAPKRLIVIHDEPIVTD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MRM1_HUMAN
Sequence: MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLLALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVCMEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 1, mitochondrial, 16S rRNA (guanosine(1145)-2'-O)-methyltransferase, 16S rRNA [Gm1145] 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YDDQ_BACSU
Sequence: MTTALLVIDIQNDYFPNGKMALTNPEKAAQNAAKLLSHFRNTGAPVFHVQHITEGNIAHFFHPNTEGVEIHESVRPLEKETVIVKHMPNSFFNTDLNGKLQEEGVKELVVCGMMSHMCIDATVRSAVEHGYVCQVVEDACATTTLQIEDKIVPAEHVHYAFMAALNGVYATVKTTEAFLK
What are the official names of this protein?
Uncharacterized isochorismatase family protein YddQ.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: SEC13_DICDI
Sequence: MATQNVDSGHEDMVHDAQFDYYGKFLATCSSDKMIKIFDVGGENPQHLVDLRGHEGPVWQVAWAHPKFGKILASASYDRKVIVWKEVGNNSWSIIHQYAGHELSVNSISWAPHEFGLSLACASSDGSVTIHNYNNNVWEAPQKIQVSQIGVNSVSWSPAAIPTSLVNSANTIIPAPIKRIVTGSCDNLIKIFKNVEDKWILDKQLEDHKDWVRDVAWAPNIGLPYSKIASCSQDRSVIVWTQDENGVWSGKPLPKFDDIVWRVSWSVIGNILAVSCGDNQVTLWKEGVDSEWKLISHVENN
What is the function of this protein?
As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
What are the official names of this protein?
Protein SEC13 homolog, GATOR complex protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Lysosome membrane.
Protein: PTH_RICAH
Sequence: MILVIGLGNPGKEYQYTRHNIGFIAIEKIANQYNSSFSTKKQFNCEIAETISDGQKIIFIKPTTYMNLSGKSVISVKTYYNINPAKIFVIHDDIDLETCRIKFKTGGGNGGHNGLKSIDGVIGNNYNRIRVGVGRPKNNQDVADYLLNNFLQSEYEIAMQAIDRIVNNFDLILENKLEKFKNKIV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGBA_HAEDU
Sequence: MKANKLSAITLCILGYAHTVYAESNMQTEKLETIVVSSEDDSVHNKNVGEIKKNAKALSKQQVQDSRDLVRYETGVTVVEKGRFGSSGYAIRGVDENRVAVVVDGLHQAETISSQGFKELFEGYGNFNNTRNGVEVENLKQAVIQKGADAIRTGSGSLGGTVSFESKDARDYLIDKNYHFGYKTGYSSADNQKLHSVTAAGRYSDFDLLAVHTQRHGNELRNYGYRHYDGSVVRKEREKADPYKITKQSSLIKIGYQLNDTNRFTLGYDDSRNTSRGTDWSNAFTSYNGGPFLKDVRHTNDQSNRKNISFVYENFDTNDFWDTLKITHNHQKIKLKARLDEYCDVNGEIDCPAIANPSGLYINDKGIFLDKHDGEITHKKEGEFNNYFDSKGKEVRVKGFNVDSILINCDQYDCSKPMQLLSSTNNGYGGSPNKYIYKTYELFEKTMNNGNGKYAVLEIRSSGHEKFSRVYLPSEKGYVENQWKDRDLNTDTQQYNIDLTKSFKLKSVEHNATYGGLYSEVKKSMTNRAGYEAYNRQWWANIFFGKENNKPNKCQPYNGNSFTTLCSHEDRLFSFLIPVKTKTGALYVTDKIKLNDKVNLDVAYRYDRIKHDPKYIPGTTPKLPTDLILGRFIEFKPKNTYATQDEKNENAEKNAVYLASKKTKFSANSYSATFSFDPMDFLKIQAKYATGFRAPTSDEIYFVFQHPSFSIYPNLYLKAERSKNKEVAITLHKQKSFLTVNLFQTDYKDFLDLAYLKKGSLPYGNGGSQLETLLYQNVNRDKARVKGLEVNSKLHLGDVWRTLDGFNLSYKLSLQKGRMSSKVGEEGKQRDTNKLDTPMNAIQPQTHVVGVGYEHPQEKFGVDMYLTHASAKKEKDTFNMFYDGKDQKDQHIKWRSDRYTLVDLIAYVKPVKNVTLRAGVYNLTNREYGTWDSIRSIRPFGTTNLINQETGKGIKRFNAPGRNFRVNAEITF
What is the function of this protein?
Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the host and is required for heme uptake.  May be involved in virulence.
What are the official names of this protein?
Hemoglobin and hemoglobin-haptoglobin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. Hemoglobin/haptoglobin binding protein subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SCL33_ARATH
Sequence: MGSYSAGFPGSLDWFDFPGLGNGSYLNDQPLLDIGSVPPPLDPYPQQNLASADADFSDSVLKYISQVLMEEDMEDKPCMFHDALSLQAAEKSLYEALGEKYPVDDSDQPLTTTTSLAQLVSSPGGSSYASSTTTTSSDSQWSFDCLENNRPSSWLQTPIPSNFIFQSTSTRASSGNAVFGSSFSGDLVSNMFNDTDLALQFKKGMEEASKFLPKSSQLVIDNSVPNRLTGKKSHWREEEHLTEERSKKQSAIYVDETDELTDMFDNILIFGEAKEQPVCILNESFPKEPAKASTFSKSPKGEKPEASGNSYTKETPDLRTMLVSCAQAVSINDRRTADELLSRIRQHSSSYGDGTERLAHYFANSLEARLAGIGTQVYTALSSKKTSTSDMLKAYQTYISVCPFKKIAIIFANHSIMRLASSANAKTIHIIDFGISDGFQWPSLIHRLAWRRGSSCKLRITGIELPQRGFRPAEGVIETGRRLAKYCQKFNIPFEYNAIAQKWESIKLEDLKLKEGEFVAVNSLFRFRNLLDETVAVHSPRDTVLKLIRKIKPDVFIPGILSGSYNAPFFVTRFREVLFHYSSLFDMCDTNLTREDPMRVMFEKEFYGREIMNVVACEGTERVERPESYKQWQARAMRAGFRQIPLEKELVQKLKLMVESGYKPKEFDVDQDCHWLLQGWKGRIVYGSSIWVPL
What is the function of this protein?
Probable transcription factor involved in plant development.
What are the official names of this protein?
Scarecrow-like protein 33, AtSCL33, GRAS family protein 12, AtGRAS-12.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_CHLPB
Sequence: MKVTPEKKKGSDTPMMRQYLEVKERYPEYLLLFRVGDFYESFYEDARKVSEALNIVLTRRSNGASADIPMAGFPHHACEGYIARLVKKGFKVTVCDQVEDPSQAKGLVRREITDIVTPGVTYSDEILDDKHNNYLCALCFMKKGRERRAGVAFIDVTTAEFRIADLQPEQVKDMLQSIQPSEILLSSRDKSYSDTVSRILPQEVVVTILDDWMFSEESASQVIERHFKTHSLKGFGIDSAFAARVAAGVVLHYLADTRQNRLQYITRIALVDARDHMTLDLQTKRNLEIISSMQDGSTSGSLLQVIDKTCNPMGARLLRRWLLRPLKRIDAIQARLDAVEVLIEEGAVRKALAEGLGGIHDLERALSRIATFRSMPREVRSLGSSLQKLPAIQALLKDSGSDRLKKLVSGLDLLDEITSIIESAIDPEAGAKLRDGGYIRSGYNAELDLLRSVSSNAKSGLMEIQQAERRKTAISTLKIQYNRVFGYYIEVSKANSDKVPDYYEKKQTLVNAERYTIAELKEYEVKILNADEKSQMLEQELFRDLCVRITACSKEIQQNAEIVAELDCLHSYACCSEAYGYVKPEVKEHGNLSIKNGRHPVLERILHVDEPYVPNDCFFDKKQRMLMVTGPNMAGKSSYLRQNGLIVLLAQVGCFVPADAAEIGLVDRIFTRVGASDNLTSGESTFLVEMNEAANILNNATGKSLILLDEIGRGTSTYDGMSIAWAMSEYIQSVVGARTLFATHYHELAELEERFDSISNYNATVVETADKVVFLRKIVRGASDNSYGIEVARMAGMPSEVIQRAKEILSGMEKRDIMISFGKECAGTIEPQSRQIYLFEEEERKLKNAIEALNINTMTPLDALLELKKLQDLAGGDG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CREB1_RAT
Sequence: MTMDSGADNQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
What is the function of this protein?
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters.  Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation.  Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity).
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14_PSEPW
Sequence: MAKKSMKNRELKRQLTVAKFAKKRAELKATIVNLNASPEERFAAVVALQKQPRDASAARLRNRCRLTGRPHGVYRKFGLGRNMLRQAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TFE_SULAC
Sequence: MLNLAKELVGDEALGLLKYLIGKKSEITDEEIAKELNTKPNEVRKYLYLLSDHGLVTYRKTKDKDSNLYIYYWKVNVNQINEILLSRKRLILEKLRNRYEQEKDGLFYFCPQDNIKYSFDDAIENEFKCLKCGTSLSQYDSEKARSFLEQKIKQIEEEINKEIRRESSKSY
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: LFTR_SYNFM
Sequence: MPVFRLTEELIFPPSYLAERDGLLAVGGDLSAERLLLAYRQGIFPWYTEKTPILWWSPDPRLVLFPAELKISISLRRVLRKNVFSVTFDRAFADVIRRCAEVRRARDDSTWIVPGMVTAYSRLHRLGYAHSVESWHEGELVGGLYGVALGRVFYGESMFTRKTDASKVALVHLVDLLTRGGFQLIDCQVTTAHLQSMGAREISRRRFLTLLAENIPEVVHGESWEGESCCGKRP
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_SALTI
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEAPVDFATLFGREAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGACLASAHEEGVENLHVMCHDAVEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVPFAELVLSKLKLGGVFHMATDWEAYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PSBN_THAPS
Sequence: METATIIVIFVSSLLVGITAYSVYTAFGPASKNLRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HIS1_ACISJ
Sequence: MTQQITLALSKGRIFEETLPLLAAAGIEVLEDPEKSRKLILPTSRPEVRVVLVRATDVPTYVQYGGADLGVAGKDSLIEHGGQGLFRPLDLKIAKCRVSVAVRADFDYREAVTQGSRLKVATKYTSIARDFFASKGVHVDLIKLYGSMELAPLTGLADAIVDLVSTGNTLKANNLVEVEQIMDISSHLVVNQAALKLKQAPLRRIIDAFASAVPQG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX28_CENEL
Sequence: TVINVKCTSPKQCLKPCKDLYGPHAGAKCMNGKCKCYNN
What is the function of this protein?
Blocks Kv1. 3/KCNA3 voltage-gated potassium channels of human T-lymphocytes (Kd=0. 71 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.8, Toxin Ce1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.