PharMolix/UniProtQA huggingface dataset:
Protein: INSI2_PONAB
Sequence: MAEGETKSPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2.  Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi.  Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2.  Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase RNF139.
What are the official names of this protein?
Insulin-induced gene 2 protein, INSIG-2.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRMA_SHIFL
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIALDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQFETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: KCY_STRPB
Sequence: MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_SHEB5
Sequence: MIGRLRGVLVEKQAPEILIDVNGVGYELQMPLTSFYELPEVNHETMVYTHFVVREDAQLLYGFITKQERALFRLLIKTNGVGPKLALTILSGMTAGEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASAGSEREFVLQSNYSPAPTVNSAEEDAISALISLGYKPPQASKSVSAAYKEGMDSETLIKAALKSML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LTOR4_XENTR
Sequence: MTSTMTQGLERIPDQMGYLVMSEDGGVLASAGDLENDERLAGVIREMVAVACSFRDLGDQQPFKRMSIVFGEHTFLVTISGQKIYVVKRQNVVREPISV
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR4, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR4 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RS10_METST
Sequence: MNKARIKLTGTDPEKIADVCNQLKKIAERTGVDLSGPIPLPTKKLVVPTRKSPDGEGKATWEKWELRIHKRLVGIEADERAMRQVMKVNVPDNVSIEIELKA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PDXH_XANP2
Sequence: MTSSTGMEAHNPLTSGDFTEVSEPFRLFAEWLAEAGKSEPNDPNAMTLATVDPDGLPDARMVLLKGLDARGFVFFTNTESAKGRELAQTPKAALVFHWKSLRRQVRVRGPVEQVTADEADAYFATRPRLSQIGAWASSQSRPLEGRFALEAAVASATAKYALGTVPRPPHWTGFRVLPVAIEFWHDRPFRLHDRVVFRREGEGADWSRTRLFP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CYSI_ECO5E
Sequence: MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: POXIN_BOMMO
Sequence: MTGIVELDLRMLKKKTAMSKRTVLNENYKGIVESMSIPAEIHERNGKKYASVGSILPIHCCPPEELERRAESTHHYCGVFTDELLAPLEELAYVRLDENTAEKVFINRAKRILIVSSDGHLAQWRCAPTFESANRYIAGTPIVDQRGGVISVVVAKKNNHYAVSSFEGEGGYFESTQNWKVVEPAAGGYAYGELTFPSRTALREHVAGLRGGAGAWGDAVPVLRGGTSPRLALVLDGRQLAHYYLHNVIVDVEYL
What is the function of this protein?
Nuclease that cleaves 2',3'-cGAMP.
What are the official names of this protein?
Poxin.
What is the protein family that this protein belongs to?
Belongs to the poxin family. Highly divergent.
Protein: KCY_ECOL6
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_YERPY
Sequence: MSQHVMFNAVLSSHPALFIQGEWRIGNGVSFEKQDPMSQQRLWQARAADHTDVTLACHAARAAFPAWARASLEQRATVIQQFAALLEQHKQSLARTISLETSKPYWETLTEVQAMIGKVAISLQAYQTRTGHSQTPMGDSMSVLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPWTAEETVKLWQQAGIPDGVLNLVQGGRETGEALAAQPDIDGLLFTGSAHTGYHLHRQLAGQPEKMLALEMGGNNALIVEQVKDRDAVVNLAIQSAFISAGQRCTCSRRLLVKTGAEGDAFLLRFTAVAQALRIGRWDEQPAPFMGAVISSQAAERMLAAQQHLLLLGGESLLNMTRPDSQSALLTPGIIDITNISEVPDEEYFGPLVSVIRYTDFTEALKIANQTRFGLAVGLVSEDRQQFEQLLLEARAGIVNWNKPLTGASSAAPFGGVGASGNHRPSAFYAADYCAWPMASLECEHLTLPATLSPGISFDLPKV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RS9_AGRVS
Sequence: MADLSSLKDLGTAQEASAPVHVRKVDAQGRAYATGKRKNAIARVWVKPGTGKITVNGRDFPVYFARPVLQMILQQPVVAAARTGQFDVIATVTGGGLSGQAGAVRHGISKALTYFEPGLRSVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NUCS_CORGB
Sequence: MRLVIARCSVDYVGRLEAHLPSADRLLMVKADGSVSIHADDRAYKPLNWMTPPCSLVETPITDEDGEATGESLWVVENKKGEQLRITVEKIHSEQNFDLGEDPGLVKDGVEDHLQELLAEHITTLGDGYTLIRREYPTAIGPVDILCRNSDGETVAVEIKRRGGIDGVEQLTRYLELLNRDELLKPVHGVFAAQEIKPQAKTLAEDRGIKCVTLDYQALRGIESNELTLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_SALTY
Sequence: MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAVVIAQAFKPKKRDLFGR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA.  Acts by oxidizing the DsbA protein (By similarity).
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_NEIG2
Sequence: MFNKYVKTFQYGNQTVTLETGEIARQAAAAVKVSMGDTVVFVAVTTNKEVKEGQDFFPLAVDYLERTYAAGKIPGGFFKREGKQSEKEILTSRLIDRPIRPLFPEGFYHDIQIVAMVVSVDPEIDSDIPAMLGASAALVLSGVPFAGPIGAARVGYINGVYVLNPTKAELAKSQLDLVVAGTSKAVLMVESEAKILPEDVMLGAVVYGHDQMQVAINAINEFADEVNPEVWDWKAPETNEELVAKVRGIAGETIKEAFKIRQKQARSAKLDEAWNAVKEALITEETDTLAANEIKGIFKRLEADVVRSQILDGQPRIDGRDTRTVRPLNIQTGVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTDRFMLHYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEITESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTTEGVTALQMDIKIQGITKEIMQIALAQAKEARLHILDQMKAAVAGPQELSAHAPRLFTMKISQDKIRDVIGKGGETIRSITAETGTEINIAEDGTITIAATTQEAGDAAKKRIEEITAEVEVGKVYEGTVVKILDNNVGAIVSVMPGKDGLVHISQIAHERVRNVGDYLQVGQVVNVKALEVDDRGRVRLSIKALLDAPVREENAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THLA_STAAC
Sequence: MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLAEQYGISREEQDTFAVNSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDGTVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFAAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
What are the official names of this protein?
Probable acetyl-CoA acyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ECOL5
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPPF_STRP1
Sequence: MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGESGSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNERATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIGIARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFISDRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHDYTLDKPSMVEIKPNHFVWANQAEIEKYQKEL
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Oligopeptide transport ATP-binding protein OppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HYPA_CHLPB
Sequence: MHEMSIAISIIDAVAAKAEAEHADTVTIVELEVGKVAGVEVESLKFCFSAAAKNTVAEGAELAVCEVEPVGECEACGQRFPVAFHVATCTSCGSFKTNIVSGRELLIKSITIE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ERA_LACAC
Sequence: MEEKEFKSGFVALVGRPNVGKSTLMNYLVGQKVAITSNKPQTTRNRISGIYTSDRMQVIFVDTPGIFKPHSKLDDYMDKASLSSLNDVDLVLFMVEPEDMGKGDQYIADLLKEVKVPVFLVINKVDQIHPNKLLPIMDSYHKLDGFKEILPISATQGIGIDDLLNTIYKYLPAGPQYYDADQITDRPEYFVVAELIREQILRLTSQEVPHATAVVVDQMNKHQNGKLVIEATIYVERDGQKGIIIGKGGKMLKQIGIDSRKEIERLLGEKVNLRLWVKVQHNWRSDPSFLKQIGYDKKELG
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: RS2_BORBR
Sequence: MSLMREMLEAGVHFGHQTRYWNPKMAPYIFGHRNKIHIINLEQTVAKYQEASKFVKQLVARGGNILFVGTKRAARELVATEAARCGMPYVDARWLGGMLTNFKTVKSSIKRLKDMEAMVADGGFERMTKKEGLLFQRELDKLNKSIGGIKDMNGLPDALFVIDVGYHKIAVAEAKVLGIPVVAVVDTNHSPDGIDHVIPGNDDSARAIALYAKGMADAVLEGREQNINGLVEEIGEGQEEFVEVQDNQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ASSY_EHRRW
Sequence: MKKIVLAYSGGLDTSVILKWLQENYNCEVVVFTADIGQEDDMSVIQKKAAALNVKEIFIEDLKEEFVRDFVFPMFRANTIYEGYYLLGTSIARPLIAKRQIEIAHLTGADAVAHGATGKGNDQVRFEFGYYCCDPNIKVIAPWRQWELTSRHSLIEYARKNNINVPLDKVNEPPYSIDANLLHISYEGKSLEDPYVEPDYTMLSRSLTPELASSIPEYIEITFEQGDPIAINDISLSPANLLHQLNKIGGKHGIGIVDIVENRYIGIKSRGIYETPGGTILLHAHRAIESITLDRESAHLKDEIMPKYAKLIYNGYWWTTERKMLQSLIDKSQEKVNGTVRIKLYKGSVIVVGRKSNNSLYSYNLASFDSESQGYDHKDAEGFIKVNSLRLKKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI47_SCHPO
Sequence: MVRDTRNVDLERGLELCKPEKVNKQNLFTNIVKPQKDKINIKTDKIKFFLNNLFTEFSKFHDSCYPDGRISTRSKLRWPLLIIWCILIVFAIDKNFEVKDFLSIWINESFINENRFYSEIWGPIAIYICLFILLLLGLIYCSKIVVKAIPLISIVIAAVVVIIAVAMVKILYICHWLIYKILILAFGIKVKPLGDTLPTHNGETGSHSKATVGSDIEQIEFQNMPTPVKK
What are the official names of this protein?
UPF0494 membrane protein C1348.07.
What is the protein family that this protein belongs to?
Belongs to the UPF0494 family.
What are the subcellular locations of this protein?
Vacuole. Membrane; Multi-pass membrane protein.
Protein: ADD_ECOL6
Sequence: MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: ARP6_DROME
Sequence: MANAVVVLDNGAHTAKVGLANQDEPHVVPNCIMKAKSERRRAFVGNQIDECRDTSALYYILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRGYVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEFVYTQDDYEEYGFQGINQR
What are the official names of this protein?
Actin-related protein 6, dArp6, Actin-like protein 13E.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with Su(var)205/HP1 on centric heterochromatin.
Protein: CLPX_HELMI
Sequence: MYKGFGDDKSQLKCSFCGKLQDQVKKLVAGPGVYICDECIELCNEIIEEELQDENTFDLGDVPKPKEIREILDQYVIGQEQAKKALSVAVYNHYKRINLGSKIDDIELQKSNIIMLGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFICGGAFDGIEKLIMNRIGKKTMGFNADIKGKQEKKIGETLREILPVDLLKFGLIPEFVGRLPVIVTLDALDEDALVRILTEPKNALVKQYQKFFELDQVQLEFTDDALRAIAQEAIKRNTGARGLRAILEEVMLDVMYDIPSRNDVTKCAVTKEVILKQKEPVLVTSDRKKKKEESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RMI2_CHICK
Sequence: MAGEAASPPLKVLAAQLRAAGRGAGGTWRLSRTETGRAPLCLRAVWMQGTVLQVERGGGGSARLRDGSGHFTVLGVEDVPRGRPCLSAGKYVMVMGMVRACSPEPVLRAIKMTDLSENPVHEEMWGLEVEELHRVIP
What is the function of this protein?
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates.  It is required to regulate sister chromatid segregation and to limit DNA crossover.  Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM.  In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
What are the official names of this protein?
RecQ-mediated genome instability protein 2.
What is the protein family that this protein belongs to?
Belongs to the RMI2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XTH8_ARATH
Sequence: METERRIITSCSAMTALFLFMTALMASSSIAATPTQSFEDNFNIMWSENHFTTSDDGEIWNLSLDNDTGCGFQTKHMYRFGWFSMKLKLVGGDSAGVVTAYYMCSENGAGPERDEIDFEFLGNRTGQPYIIQTNVYKNGTGNREMRHSLWFDPTKDYHTYSILWNNHQLVFFVDRVPIRVYKNSDKVPNNDFFPNQKPMYLFSSIWNADDWATRGGLEKTDWKKAPFVSSYKDFAVEGCRWKDPFPACVSTTTENWWDQYDAWHLSKTQKMDYAWVQRNLVVYDYCKDSERFPTLPWECSISPWA
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 8, At-XTH8, XTH-8.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: DXS_SHEWM
Sequence: MSLDISQYPVLAQANTPDELRQLPQAVLPQLADELRGFLLKSVGKSSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDAMHTIRQKGGIHPFPWREESEYDTFSVGHSGTSISAALAMAVAAEKEQAGRKVVSVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTIRESSKKVLKGMPVIKEMAKRTEEHLKGMVVPGTMFEELGFNYIGPIDGHDVDALVETMRNMRNLSGPQILHIMTKKGRGYEPAEKDPIGWHAVPKFDPSTFEKPASKPSNPTFSQVFGKWLCDVAEKDKKVLGITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLGAGFACEGLKPVVAIYSTFLQRGYDQLIHDVALQKLPVLFAIDRGGIVGADGPTHQGAFDLSFMRTVPNMVIMAPSDENECRQMLYTGYCYNDGPTAVRYPRGSATGAPQIEEMTALPIGKGLIKRQGQKVAILNFGTLLASVLTAGESLDATVADMRFVKPLDVELIKELANSHDVLVTVEENAIMGGAGSGVLELLQQLKQPMPVLQLGLPDEFIKHGDSGEIIAELKLDAAGILEQIESYLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PXPA_CAMJE
Sequence: MFKVDLNSDLGESFGAYKMGMDEEILKFVSSVNVACGFHAGDPCVMDETLNLAKQNGVCIGAHPSYPDLLGFGRRNMQISFEEAKNYALYQLGALFGFAKAKGMKIQHFKAHGALYNMAAIDENLALALCEAVASFDENIIFLGLSNSAMNEAAKKKGLRYANEVFADRAYNDDGTLVSRKLEGALIHDENLAIKRVIKMIKESKVTSINGKEIDLKADSICVHGDNAKALEFVKKIKENLKKEQIQICALENFI
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.