PharMolix/UniProtQA huggingface dataset:
Protein: FLAB3_TREMA
Sequence: MIINHNMSSMYANRMLGINNDQVQGNIEKLSSGQRINRAGDDASGLAVSEKMRMQIRGLNQAQKNIQNGVSFIQATEGYLQETTDILGRIRELSIQSANGIYSDEDRMQIQVEVSQLIDEVDRIASSAQFNGMNMLTGAFAANSVSGRIMQFHIGANVDQNARVYIGTMTAQSLGLVGTQGDAFAKLSIASPESANMAIATLDSALTSVNKQRADLGAYQNRFEMAAKGIGIASENLQAAESIIRDTDMASEIVDYTKNQILTQSSVAMLAQANTQAQNVLPLLS
What is the function of this protein?
Component of the core of the flagella.
What are the official names of this protein?
Flagellar filament 30.7 kDa core protein, Flagellin subunit protein B3.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: NU3C_OLIPU
Sequence: MFLLYEYDIFWAFLIISSAIPVLAFLISGVLSPIRKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEALIFVLILILGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ENGB_STRPZ
Sequence: MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEYLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ARLY_ACISJ
Sequence: MSSSSASQPSHDQLATKAQAWSALFSEPMSDLVKRYTSSVFFDKRLWQADIAGSLAHAEMLAAQGIISAQDHADIQKGMAQITQEIASGAFEWKLDLEDVHLNIEARLTQLVGDAGKRLHTGRSRNDQVATDVRLWLRGEIDLIEGLLSELQLSLVEVAEQNVEVILPGFTHLQVAQPVSFAHHLLAYVEMFARDAERMRDVRRRVNVLPLGSAALAGTTYPLDRERVAKTLGMEGVCQNSLDGVSDRDFAIEFTAAASLCMVHVSRLSEELIIWMSQNFGFIKIADRFTTGSSIMPQKKNPDVPELARGKTGRVVGHLMGLITLMKGQPLAYNKDNQEDKEPLFDTVDTLKDTLRIFAEMIGGQMNPATGCKDGGITVNAEAMRAAALKGYATATDLADYLVKKGLPFRDAHETVAHAVKAAVSHSVDLSELPLAVLQGFHPAIEKDVFDALSLQGSLNARNTLGGTAPAQVRTQLARHRARLSA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SHIFL
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ELUMP
Sequence: MKQILILDFGSQYTQLIARRLREEQIYCEILPFNTKYEDIIALDPAGVILSGGPSSVYGAGAPKPDPKIFSIDKPVLGICYGMQLLAVNGGGKVTACKKREYGFAEVKIKASTSKLLKGMPKKFTAWMSHGDGVHAMPKNFKVTATTSTSPFSAAEDDKNKRYAVQFHPEVVHTAHGSKILKNFARVICGYKEKWTPASIMTASIAAMKKQIGKGHVICGLSGGVDSSVVAALLAKAIGKNLYCIYVDTGLLRTGDRERTEGLAKKLKVNLKIVDAEKLFLTKLAGVTDPEKKRKIIGALFIEVFEKEAKKFKDAQFLAQGTLYPDVIESMSVKGPSDVIKSHHNVGGLPEKMNLKLVEPLRFLFKDEVRALGRELGLGSEIVDIHPFPGPGLAVRILGAVNKPDLDTLRAADFIVREELYKSGWDKKSWQAFAVLLPIKTVGVMGDERTYEKAACVRCVNSVDGMTADWTKLPYDVLQKISGRIISEVRGINKVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ISPDF_BRUA2
Sequence: MAAGRGERAGQSAEGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEKHENVILVTGGPTRQESTRLGLLALKDEAPQYVLIHDGVRPFIGQDLLERIIANLTPDNGVLPALAVSDTLKRAAADGMVETTISRTGLFAAQTPQAFPYAPILDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDHAVFPDIRTGNGYDVHSFEPGDHVTLCGVKIPHEAKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIANVDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATATVIYPGEVPE
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: CORO7_RAT
Sequence: MNRFKASKFRHMEARPSRREAWISDIRAGTTATCGNHIKSSCSLIAFNSDRPGVLGIISLEGHEENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSSTGEALPSVPGVVLGPEELPVDVLQFHPTADGVLVSTAGRTVKVWDVAKQQHLTELEAHKDLVQSAVWSRDGATVGTACKDKQLRIFDPRARAQASQSTQAHENNRDIRLAWTGIQEYLVSTGFNQMREREAKLWDTRVFSSALASITLDTSPGSLIPLLDPDSGLLVLAGKGENQLYCYEVTPQQPALSPVTQCILENALRGAALVPRQALAVMNCEVLQVLQLSDTAIIPISHRVPRKAVEFHEDLFPDTAGSVPASDAHTWWAGDNQQVQKVSLNPAHRPHPRFTSSLLPTLEPSPNMEQPAELPRADTELSEGFSSPSSLVSPSTPSSLGLSLSSTSGIGTSPSQRSLQSLLGPSSKFRHAEGTILHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELQKPGRLPDTALPTLQNGAAVMDLVWDPFDPHRLAVAGEDARIRLWRVPPGGLKNVLTTPETVLTGHTEKIYSLRFHPLAADVLASSSYDLTIRIWDLQAGTEQLRLQGHQDQIFSLAWSPDGKQLATVCKDGRVRVYDPRSSPLPLQDGPGPEGGRGARIVWVCNGGCLLVSGFDSRSERQLQLYMADALAEGPSALLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYEVIPEAPFFLECNSFTSPDPHKGFILLPKTECDIQDVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWASALDAKAWFKGANGQPRLLSLQPPGMTPVSQAPREVPARRTPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDPLPQDSFEGVDEDEWD
What is the function of this protein?
F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking.  May play a role in the maintenance of the Golgi apparatus morphology (By similarity).
What are the official names of this protein?
Coronin-7, Crn7, 70 kDa WD repeat tumor rejection antigen.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments (By similarity).
Protein: NDB42_OPIMA
Sequence: MKTQFAILLVALVLFQMFAQSEAIFGAIWNGIKSLFGRRALNNDLDLDGLDELFDGEISQADVDFLKELMR
What is the function of this protein?
IsCT2f shows neither hemolytic, nor antibacterial activities, surely due to the fact that it cannot apply amphipathic alpha-helical structure.
What are the official names of this protein?
Cytotoxic linear peptide IsCT2, Non-disulfide-bridged peptide 4.2, NDBP-4.2, Non-disulfide-bridged peptide 5.3, NDBP-5.3.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: GLCD1_VULM7
Sequence: MKAVTVIPLVKDSLALRDMPKPSPKRYQVLLSPIEVGVCGTDKDIIEGRYGAPPPGEEYLILGHESVAEVVELGDDVDNVSVGDIVVPTVRRPTTCTLPITEVDYCPRGTYAEHGIWYLHGFATEFAVTDSQYLVKVPKEAIDVAVLTEPLSIVEKGIDLALRLGKARFESWSPRRVLIMGAGPIGMLALMVMRLRDFADITVTATRPYDSLKAKLVREIGATYVNTNIDQINGDFDIVIEATGSTSAAYDALRHLGADGVAVLLGIYLDSKNVNIRPLLDDWRRNKLIIGATNASIGAFEMGVADLVKAKFEFGGWVRKLITKEVTLDEYEYAYNWGHEDIKSVIQIRSL
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone.  Can utilize both NAD(+) and NADP(+) as electron acceptor.  Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
What are the official names of this protein?
Glucose 1-dehydrogenase 1, GDH 1, GlcDH 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
Protein: PSG8_HUMAN
Sequence: MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSGKRIPVSLAIGI
What are the official names of this protein?
Pregnancy-specific beta-1-glycoprotein 8, PS-beta-G-8, PSBG-8, Pregnancy-specific glycoprotein 8.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Secreted.
Protein: XKS1_NEOFI
Sequence: MTSQGPLYIGFDLSTQQLKGLVVNSELKVVHVSKFDFDADSHGFSIKKGVLTNEAEHEVFAPVALWLQALDGVLDGLRKQGLDFSRVKGISGAGQQHGSVYWGENAESLLKSLDSSKSLEEQLSGAFSHPFSPNWQDASTQKECDEFDAFLGGPEQLAEATGSKAHHRFTGPQILRMQRKYPEVYRKTARISLVSSFLASLLLGYIAPMDISDVCGMNLWDIKKGAYNEKLLGLCAGPFGAEDLKRKLGDVPEDGGLRLGKINRYFVERYGFSSNCEILPSTGDNPATILALPLRPSDAMVSLGTSTTFLMSTPSYKPDPATHFFNHPTTPGLYMFMLCYKNGGLAREHVRDAINEKSGSGASQSWESFDKIMLETPPMGQKTESGPMKMGLFFPRPEIVPNVRSGQWRFTYDPASDTLTETEDGWNKPSDEARAIVESQMLSLRLRSRGLTQSPGDGLPPQPRRVYLVGGGSKNKAIAKVAGEILGGSDGVYKLDVGDNACALGAAYKAVWAIERKPGQTFEDLIGQRWREEEFIEKIADGYQKGVFEKYGKAVEGFERMEQQVLKQEAARK
What is the function of this protein?
Highly specific D-xylulose kinase which participates in the catabolism of xylose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose kinase A, Xylulokinase A.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_PROM1
Sequence: MSYLIPGELIPEDGFIELNKGRETTTLKVANTSDRPIQIGSHYHFFESNKGLEFDRKKSLGKRLDIPAGTAIRFEPGDQREVNLVPYAGDRKIFGFNGLINNSLQQ
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_STRP2
Sequence: MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVISTWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLLANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDGAVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQDTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: POB3_KLULA
Sequence: MSTDFDRIYYNQSKLGGRFRLAEGGLGWKASATGGSASTQNNEPLLLAADEVSSVQWSRGCRGYELKISTKNKGLIQMDGFQQEDFNLLKNDFQRRFNMQLEHREHSLRGWNWGKLDLARNEMVFSLNGKPTFEIPYTHINNTNLTAKNEIALEFDTQNEAYNPAGDELVEMRLYVPGTVEENEDQDQIMVKDEAEAEDGVKSEVKTEEGSEEPDVQEEKTLAEYFYEELRSKADIGEISGDAIISFQDLFFTTPRGRYDIDIYKNSIRLRGKTYEYKLQHRQINRIFSLPKADDIHYLMVLSIDPPIRQGQTSYPFLVLQFQKDEETEVQLNVEDDEFEKLYKDKLKKQYDAKTHIVLSHVLKGLTGRRVIVPGEYKSKYDQCAVSCSYKVNEGHLYPLDNAFLFLTKPTLYIPFQDIAAVNISRAGQTSTSARTFDLEVVMRANRGTTTFANISKEEQQLLETFLRSKNLRVKNEDKEAEQRLQTAFGSDSDDDDVDINMGSAGEDEESVDEDFHASDEDDDVAEEFDSEASASDSEGETSKSERPSKKAKLE
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit POB3, Facilitates chromatin transcription complex subunit POB3.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: RNH2_THEAC
Sequence: MTESERQCGIDEAGRGPVIGPMVISLVCCDLSFLKEIRVKDSKALTRKRRSELFEKIMGRCSVRYRILHPKDLNRMMAAESLNKIEEDEIVDLLRYADDLVYIDCYDVIEERAQEIIQMRSGRQVVCKHKADAIFPAVSAASIVSKVIRDAEIDRLHDRFGDFGSGYPSDPRTIDFLKKYLKENQDPSEIVRIHWSTVQRLLHSEKNQKKLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_BACCR
Sequence: MISVNDFRTGLTISVDNALWQVLDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGEAHVFMDNGTYEQIELGEKQIERELKFLKENMEVAIMTYQGEVLGVELPNTVELQVTETEPGIKGDTASNVTKPATLETGLVVQVPIFINEGEMLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PARXL
Sequence: MSAPATDLSAGAPSGRRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYVGADDTHGTPVMLRAEKEGLTPKQLIDRVWQEHKRDFDSFGISFDNYYSTDSEENRVLSENVYLALKEAGLIDARDIEQAYDPVKEMFLPDRFIKGECPKCGAKDQYGDSCEVCGSTYLPTELINPYSVVSGATPVRKTSTHYFFRLSDPRCENFLRAWVGGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLAEKRGLDFDAWVRKGSKAEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSVIETGLNPEWLRYYFAAKLNSTMEDLDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMQHPLLASLRAAVPQIAANYEAREYNRALRQTMELADAVNAYVDTAKPWDQAKDPANGVALHETCSVSIEAFRLLSLALKPVLPKLAEAVEGFLAIQPLVWADANVPLSSTRPINAYKHLMTRVDPKQIEALLAANRDSLQATPEAAAPADAKGKSKAAKAAAGKDETPGIISIDDFAKIDLRIAKIVDCKAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYVLEPDSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLD2_XENTR
Sequence: MYPNSPSQGRIPLPLPCEQQQPPLEQSQEQPLQPQPLQPQQASGYLSKLPVSVAPELLSPEQFIQASINLHNNVNFARMLMNANLLAVPPVSPPPWSYRDQSPLISPASPSSSFQNRKRRSDEGNIAYDVKRQKFQSPQEQTVNHQAVPLRGDLGCSYPGSPAFPLLQSPSPPVLKGHVPNSGECWLYDHVDTTLPVAKDKLSKQILELFQALQQQVCDLKKKDICRAELQREIQQIFPQSRLYLVGSSLNGFGTRSSDADLCLVLKDEPMNQHTEARHILSLLHKHFYTRLSYIERPQFIKAKVPIVKFRDKVSGAEFDLNVNNVVGIRNTFLLRTYAYIENRVRPLVLVIKMWANYHGLNDASRGTLSSYTLVLMALHYLQTLPEPIIPSLQKKYPECFDSTMQLHLVHHAPRNIPKYLSKNETPLGDLLLGFLKYFAIEFDWSKDIISVREAKALPRSDDYEWRNKFICVEEPYDRTNTARAVYERQKFDMIRAEFLRAWVALRDNRDLYSLLPWKGIMKKMNSL
What is the function of this protein?
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail.  In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs during oocyte maturation.  Plays a central role during oocyte maturation by mediating polyadenylation of dormant mRNAs, which contain 5'AAUAAA-3' sequence in their 3'-UTR.  In immature oocytes, polyadenylation of poly(A) tails is counteracted by the ribonuclease parn.  During maturation parn is excluded from the ribonucleoprotein complex, allowing poly(A) elongation and activation of mRNAs.  May not play a role in replication-dependent histone mRNA degradation (By similarity).
What are the official names of this protein?
Poly(A) RNA polymerase GLD2, PAP-associated domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BRUA2
Sequence: MSISASLVKELRDLTGAGMMDCKAALAATEGKIEAAVDWLRAKGIAKADKKAGRTAAEGLVGVAASGNKAVVVEVNSETDFVARNDAFQELVRKIAQAALSTDGSSEAVANANVDGKTVTEAAKDAVATIGENISFRRSAALSVPQGVVATYIHNGVADGLGKLGVLVAIETAGDAEAAQAFGRQVAMHVAAVNPLALTSADVNPEAAEREKAIFIDQARQSGKPDNIIEKMVEGRMRKFYEEVVLLSQAFVINPDLTVEAALKDAEKAIGAPAKITGFARIALGEGIEKEESDFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PH4H_PSEAE
Sequence: MKTTQYVARQPDDNGFIHYPETEHQVWNTLITRQLKVIEGRACQEYLDGIEQLGLPHERIPQLDEINRVLQATTGWRVARVPALIPFQTFFELLASQQFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLTNPWFAEFTHTYGKLGLKASKEERVFLARLYWMTIEFGLVETDQGKRIYGGGILSSPKETVYSLSDEPLHQAFNPLEAMRTPYRIDILQPLYFVLPDLKRLFQLAQEDIMALVHEAMRLGLHAPLFPPKQAA
What are the official names of this protein?
Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: TSPO_RAT
Sequence: MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
What is the function of this protein?
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial.  It is apparently not required for steroid hormone biosynthesis (By similarity).  Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme.  Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:2555358).
What are the official names of this protein?
Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Protein: EIF3B_RAT
Sequence: MQDAENVAAPEAAEERAEPARQQPVSESPPTDEAAGSGGSEVGRTEDAEEDAEARPEPEVRAKPAAQSEEETAASPAASPTPQSAQEPSAPGKAEAGGEQARHPSARAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 subunit 9, eIF-3-eta.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.