PharMolix/UniProtQA huggingface dataset:
Protein: PURR_ECOHS
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: PSF2_COCIM
Sequence: MAFPLPRGVTPSEITFLCEMEMVTIVPRQRLEGLELLGGPTEPLIPPRRSSLPLWLALLLKRQRRANILPPPWLNTEWLSEFLKAETDHDVFLPPPPLDCASYTGSVARRDARRSGHSGPRRTLDGQRYIPSAPFLLQNVVDDESTAPRNPWLPYHWLELATMLLETASDDLVEPDQIRRIIRDIREIRMAKMRKFTEYVDATAIGGGEGLPLTGVGAMEIGEARGFMSGAAETLRQIGASKEEALREQAEAGDDLRNDYDEDDEMEL
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_CHLT2
Sequence: MNIAKQQQAFLGIDYGKKRIGLAFASSPLLIPLPIGNVEARSSLTLTAQALVSIIKERAVTTVVFGNPLPMQKAYASSVQSEIQELAALIQEMTAIEVILWDERLSSAQAERMLKSDCGLNRKQRKNSSDSLAATLILSSFLDSRKLY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGH3B_BACO1
Sequence: MKNIKKMVLVSAFAGTCLTPHAQTASPVIPTDPAIETHIREWLQKMTLEQKIGQMCEITIDVVSDLETSRKKGFCLSEAMLDTVIGKYKVGSLLNVPLGVAQKKEKWAEAIKQIQEKSMKEIGIPCIYGVDQIHGTTYTLDGTMFPQGINMGATFNRELTRRGAKISAYETKAGCIPWTFAPVVDLGRDPRWARMWENYGEDCYVNAEMGVSAVKGFQGEDPNRIGEYNVAACMKHYMGYGVPVSGKDRTPSSISRSDMREKHFAPFLAAVRQGALSVMVNSGVDNGLPFHANRELLTEWLKEDLNWDGLIVTDWADINNLCTRDHIAATKKEAVKIVINAGIDMSMVPYEVSFCDYLKELVEEGEVSMERIDDAVARVLRLKYRLGLFDHPYWDIKKYDKFGSKEFAAVALQAAEESEVLLKNDGNILPIAKGKKILLTGPNANSMRCLNGGWSYSWQGHVADEYAQAYHTIYEALCEKYGKENIIYEPGVTYASYKNDNWWEENKPETEKPVAAAAQADIIITCIGENSYCETPGNLTDLTLSENQRNLVKALAATGKPIVLVLNQGRPRIINDIVPLAKAVVNIMLPSNYGGDALANLLAGDANFSGKMPFTYPRLINALATYDYKPCENMGQMGGNYNYDSVMDIQWPFGFGLSYTNYKYSNLKVNKPTFNADDELIFTVDVTNTGKVAGKESVLLFSKDLVASSTPDNIRLRNFEKVSLEPGETKTVTLKLKGSDLAFVGYDGKWRLEKGDFKIKCGDQWMDIVCDQTKVWNTPNKNTLHK
What is the function of this protein?
Catalyzes the hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose in xyloglucan degradation, leading to remove the backbone 'G' units.
What are the official names of this protein?
Beta-glucosidase BoGH3B, Glycosyl hydrolase family protein 3B, BoGH3B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Periplasm. Note=Periplasmic localization is predicted by analogy with the archetypal sus locus.
Protein: TTCA_SHISS
Sequence: MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXSB_PSEAE
Sequence: MLLPLALLLGGCVSQPAPMSPKVTVGGSVGGVSLQARQAQLRLRLYAVVQGRMQTIAERRYRVSGLPLRYAFDLEVDRLEGEALYLRTELSWVGVAAVQASAWQQVAAGVDERVRLVRRDCFPNCTAARPEERSGND
What is the function of this protein?
Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:25690097).  Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane (PubMed:25690097).  Necessary for full in vivo virulence (PubMed:25690097).
What are the official names of this protein?
Type 3 secretion system pilotin, Exoenzyme S synthesis protein B, Pilotin.
What is the protein family that this protein belongs to?
Belongs to the ExsB/YscW family.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Could be a lipoprotein.
Protein: CFXQ_TRICV
Sequence: MSSMDTSVNLQEEYNKTEIAKILNLLNEELVGLVPVKSRIREIAALLLIDKLRKNLGITAGSPGLHMSFTGSPGTGKTTVGLKMSDILFQLGYIKKGHLLTVTRDDLVGQYIGHTAPKTKEVLKKAMGGVLFIDEAYYLYKPDNERDYGSEAIEILLQVMENQRDDLVVILAGYKEPMDKFYESNPGLSSRIANHIDFPDYTVEELLKISKMMLEEQQYQLTTQAEVALTQYIAKRKEKPLFANARSVKNALDRARMRQANRIFDSRGQILTKKELVNIEAEDILQSTIFD
What is the function of this protein?
Necessary for the expression of RuBisCO.
What are the official names of this protein?
Protein CfxQ homolog.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LSM3B_ARATH
Sequence: MSGEEEATVREPLDLIRLSLDERIYVKLRSDRELRGKLHAFDQHLNMILGDVEETITTVEIDDETYEEIVRTTKRTIEFLFVRGDGVILVSPPLRTAA
What is the function of this protein?
Component of LSM protein complexes, which are involved in RNA processing.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay.  The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts.  Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs.  LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mRNAs through the stabilization of the spliceosomal U6 snRNA.  Plays a critical role in the regulation of development-related gene expression.
What are the official names of this protein?
Sm-like protein LSM3B, AtLSM3B, U6 snRNA-associated Sm-like protein LSM3B.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UXAC_SALSV
Sequence: MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: LPT_YERE8
Sequence: MQYISLNTTIITTTETTGYGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: 2A5G_RABIT
Sequence: MLTCNKAGSRMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYSLCSHASTVSMPLAMETDGPLFEDVQMLRKTVSDEARQAQKDPKKERPLARRKSELPQDPHTKKALEAHCRADELVPQDGR
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  The PP2A-PPP2R5C holoenzyme may activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation.  PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B'-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere.
Protein: RS15_OENOB
Sequence: MALTQEAKNQIIKEYARHNGDTGSVEVQVAVLTADINELNNHMSENKHDFSSQRGLMKKIGHRRNLLRYLRDIDVARYRTLISKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SERC_XYLFA
Sequence: MTMRIFNFSPGPATLPEPVLRQAQDEMLEWNAVGASVMEISHRTVEFMELAKGIESDLRCLLGVPDDYAVLFLSGGATTQQALLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVADGERGGFQHIPSRAGWRLSKDAAYVHMTANETIHGVEFRQTPDVGDVPLFADFSSSIAADLIDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPTFNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPFFLPNVEQDARFAAEAKAAGLLSLKGHKALGGIRASLYNAMPLAGVQALVAFMHDFQQRYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_CLOTE
Sequence: MKEILEKIKKNAIEELNNVVDKETIESIRVKYLGKKGELTKILRGMGGLSAEERPIVGKLANEIRKNIEEIIETTLKEIKEKEKNIKLSEETIDITLPGKRQYLGKRHPLEQTLDKMKEIFINMGFTVEEGPEIELDYYNFEALNIPKNHPARGEQDTFYINDNVVLRTQTSPIQIRTMESQKLPIKMIAPGKVYRSDSVDATHSPIFYQMEGLVVDKGVTFADLKGTLDMFAKKMFGEDLKTKFRPHHFPFTEPSAEMDATCFVCHGEGCKVCKGEGWIEILGGGMVHPQVLKNCGIDPEVYSGFAFGFGVDRMVMQKYGIDDIRLLYESDMRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3737_CYAP4
Sequence: MTRIAYLDCPTGISGDMCLGALLDGGVPLDYLQHHLQGLGIAEEFSLSWHKVEHQGQQASKAEVQLRAHGHHHHPPARHWPDIVALIQQAGLPLRAEAWSLAIFRELALAEAAVHGVAAEQVHFHEVGATDALVDIVGTCLGLDWLGIEELYCSALPTGGGTVKAAHGRLPVPVPAVLQLWQKFHVPVYSNGIERELVTPTGAAIAVTLASQFGPPPPLQLEKIGLGAGTQELPLANILRLWIGQKATQAAVPQGQDGSDRVEEIILLETQIDDLNPQAIGYTMEALFAAGAVDVFTQAIGMKKSRPGVLLSVVCTAETVESCETVLFRETTTLGIRRSQQQRRILARQIQTLDTRYGPIRLKIAYQQGKIVNVQPEFEDCAQVAKQQDLPWQQIHQLALSTWYQHQPSP
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: YCDX_SALCH
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDRILNVSPQRLLAFLESRGMAPVPEFAEL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: TRUA_SPHAL
Sequence: MTRFALTIEYDGRPYMGWQRQAHGPSVQQAIEEAIHRFTAEEVQVLSAGRTDAGVHAIAMRAHVDIEKPLTPFKLTEALNAQLRPAPIAVIGCEVVPDDWHARFACIGRSYEYRIVNRRAPLTWDKGLAWQVARPLDVDAMHEAAQQLIGLHDFTTFRSAHCQSQSPVKTLDRLTVSRHGEEVIIEAAARSFLHHQVRSMVGSLALVGHGKWSARDLKAALEAADRQALGLNAPPDGLYFVGAVYP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DTD_BACAC
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAG2_XENLA
Sequence: MTLRIVTPGSNTSLIQPGFSLLHFSSHVFYLGQKGWPKRSCPTGVFLLDLKNNDLKLRPATFTNDSCYLPPLRHPAVCSFSASQGGEITQYLIHGGKTPNNEISHKLYIMTMAFPVNKRFSLCCSEKDLAGDVPEARYGHSMNVVFSRGKNAVVMFGGRSYMPLNQRTTENWNNVIDCEPLVYLIDLQFGCSTSFNLRELQDGLSFHVSLARNDTVYIFGGHSLGNNFRPPNVYKIKVDLPLGSPAVSCTVINSKISFSSSIVTQTSPDEFVIVGGYESDSQKRLICNGVFLDDETIDIQEIETPDWTGEIKHSKTWFGADMGKGAVLFGIPVDNKHQSTDCSFFFYVLNFGDNDPALQTCSQGSTEEQEDSMPLEDSEEFTFNRDGNIFDEDTYNEDDEDDESVTGYWIKCCPDCDMDRNTWEPFYSTELNKPSMIFCSKDGGHWVHSQCMDLSETMLKYLSQNNIKYFCNEHVEVARGVQTPEKTPPVKKTSLKSVRKRTTINRLSAVKKSFLRRLFE
What is the function of this protein?
Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination.  V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments.  DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.  In the RAG complex, rag2 is not the catalytic component but is required for all known catalytic activities mediated by RAG1.  It probably acts as a sensor of chromatin state that recruits the RAG complex to H3K4me3 (By similarity).
What are the official names of this protein?
V(D)J recombination-activating protein 2, RAG-2.
What is the protein family that this protein belongs to?
Belongs to the RAG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEC_RALPJ
Sequence: MKKRAIVLLSGGLDSATVLAMANADGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHEIVDLDLRKFGGSALTDDALDVPTDGVQSGIPITYVPARNTIMLSLALGWAEAVGARDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGERIRVNAPIINMTKAEIIQAGVRLGVDYGLTVSCYKADDAGRACGVCDSCRIRKAGFEAAGVPDPTRYV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: FLIM_PSEAE
Sequence: MAVQDLLSQDEIDALLHGVDDGLVETEVEATPGSVKSYDLTSQDRIVRGRMPTLEMINERFARYTRISMFNLLRRSADVAVGGVQVMKFGEYVHSLYVPTSLNLVKMKPLRGTALFILDAKLVFKLVDNFFGGDGRHAKIEGREFTPTELRVVRMVLEQAFVDLKEAWQAVLEMNFEYVNSEVNPAMANIVSPSEVVVVSTFHIELDGGGGDLHITMPYSMIEPIREMLDAGFQSDHDDQDERWIKALREDVLDVQVPLGATVVRRQLKLRDILHMQPGDVIPVEMPEHMVMRANGVPAFKVKLGAHKGNLALQILEAVERSR
What is the function of this protein?
FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliM.
What is the protein family that this protein belongs to?
Belongs to the FliM family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Protein: GLNE_YERPA
Sequence: MLPLPSELQIQAQSIKQRFSELPAPPDLRDEDIAVLALSDFVSDMLLIHPQWLEELHQQPPQPQEWQYYSQWLSQALAGVQDEAALLTALRLFRRRVMVRIAWSQVLQTSGTAETLQQLSTLAESMIIAARDWLYQVCCRELGTPCNRQGVPQPLLILGMGKLGGGELNFSSDIDLIFAYPENGQTQGGRRELDNAQFFTRLGQRLIKALDQHTIDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGGADDPYSQELRQMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFITQVFQLIRGGREPRLQERALLPTLQAVAELGLLPEQQVADLSGSYLFLRRLENLLQAIADEQTQTLPNDPLNQARLAWGMGYADWAAMSTALENHMQAVRVVFDDLIGDETPDIGEDPSHGLYKSLWQDVLEESDLAPLTPHLEEAARRQLLATISGFRHDVDKRTIGPRGREVLDQLMPRLFAEVCPRPDANVALSRLILLLLSIVTRTTYLELLVEYHAALKHVIRLCSASPMVASQLARYPLLLDELLDPQSLYQPLAPSAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQQLRIAAGDITEALPVMKVSDHLTYLAEAIIDAVIQQAWNQMVARYGQPSHLQQSEGRGFAVIGYGKLGGWELGYSSDLDLVFLLDCPLDVMTDGDRSIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGEAGMLVSTIEAFADYQRNEAWTWEHQALVRARIVYGSPKLHQQFDAIRQQILCRHREDPQLQQEVREMREKMRNHLGSKQRDIFDIKADAGGITDIEFIAQYLVLRYAASEPRLTRWSDNVRIFESMAHYDIMSPEEAAALTRAYVTMRDEIHHLALQEQSSKVAADSFIAEREQVAASWHKWLAANDANVS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: FUT9_CRIGR
Sequence: MTSTSKGILRPFLIVCVILACFMACLLIYIKPTNSWVFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNEKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDYNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth.  Also fucosylates di-, tri- and tetraantennary N-glycans linked to glycoproteins and the inner lactosamine unit of the alpha2,3-sialylated polylactosamine resulting in sLex (CD15s) epitope synthesis.  Furthermore, it is capable to synthesizes Lewis a (Lea), although to a lesser extent than Lex and Lewis y (Ley) and to confer SELE-dependent, but not SELL- and SELP-selectin-dependent, cell rolling and adhesion by enhancing Lex and sLex synthesis.  May also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE.
What are the official names of this protein?
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, Fucosyltransferase 9, Fucosyltransferase IX, Fuc-TIX, FucT-IX, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Golgi apparatus membrane.
Protein: RL6_THEPX
Sequence: MSRIGRLPIEIPKGVEVKVTPDNVVTVKGSKGTLEKKFPPIVNIEVKDNQVIVTRKGDDKEEKAMHGTTRAIIANMVKGVTEGFEKALEIVGIGYRAAKQGKKLVLNVGYSHPVEIEEKPGIEIIVEGNNKIIVRGIDKEKVGQVAANIRRVREPDAYQGKGIRYAGEVVRLKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DAPA_ANADE
Sequence: MRRLEGSMVAIVTPMKDGAVDLRALRELTEWQLAEGTDGIVPCGTTGEGVTLTPAERADVIRTVIETVRGRALVIAGAGSNATHEAIESVKLAKSLGADAALVVTPYYNKPTQEGLFRHYQAIWEATRFPVVAYNVPSRTSVDLLPETVARLAKAGAIAGIKEATANMDRQVQLVEKVGKDAIAYLSGDDFTVLPYIACGGHGVISVIANVAPRAMKELVVAARSGDLAGALAKQAAMAELNRMMFVETNPGPVKAAVALLGRAGGELRLPLAPVSEASLAKVREAMVRFGLKLA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIS_SALDC
Sequence: MLAFTLRFIKNKRYFAILAGALVIIAGLTSQHAWSGNGLPQINGKALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVKGAQDARALGKAFSADIQNYNLYSSNTVRTIQSATWFSAGRSLTVDKKMMDCGSGIYASINTLLKKSQNKNIVIFTHNHCLTYIAKNKRGVKFDPDYLNALVMHAENGKLFLDGEFVPG
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.