PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_STRPM
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQALAVKMYEQAVAAQQAAQGAEGAQANDSANNDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS14_STRPF
Sequence: MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSNPNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: O26G_CONTE
Sequence: MEKLTILLLVAAVLMSTQALVERAGENHSKENINFLLKRKRAADRGMWGECKDGLTTCLAPSECCSEDCEGSCTMW
What are the official names of this protein?
Conotoxin Gla(1)-TxVI, TeA52.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BRXC_BACCH
Sequence: MQIQKMFEKEINRDIKGVIKVGQDDDKNIYQELDEYVVTNELLHHMGEFFKSYKKGITGHTDKMGVWISGFFGSGKSHFLKILSYLLENKHVMDENEINKDAISFFNNKILDPMVLADMKLAGNTTTDVILFNIDSKSESDSKSDKNAIVKVFNKVFNEMQGFCGSIPWIADLERQMVKDGRYEEFKAEFEKISGNTWEEAREDFYYEEDSIIEALSKTTKMSEDAARNWYERAEEDYFISIDRFAKRVREYVEAKGNNHHVVFLIDELGQYIGNDSQLMLNLQTVVEDIGTQCGGKVWVLVTSQQDIDSVVKVNGNDFSKIQGRFDTRLSLSSAHVDEVIKKRILLKNEVGKQTLRLLYGDNSSILKNLITFSGDTAEMKIFNNEEDFVDVYPFIPYQFNLLQKVFTGIRIHGASGKHLAEGERSLLSAFQESAMKYAESETGALIPFSAFYQTIEAFLDSSIRTVIIHAQNNSRLNAYDVEVLKLLFLIKYVKELPANLENLATLMIQNISDDKIELKKKIESSLIRLSKETLIQKNGQEYIFLTNDEQDVNREIKNMHVDSAEVIQKIGDVIFNVVYQDKKYRYSPKYHFSFNTIIDDRPIGMQTNDIGLKIITPYFDATTELNDSELKMMSMRESNVILKLPQDTSYLDEMTEILRIQAYLKIKSGTAASQAIEDIKVRKSREANERKDRVHIYITEALKHAQIFVNSQQLDVKEKNPVERINDAFKVLIDNLYNKLHYVKKFIDTAKQLNELLVENTTQLTLSDDNEDANQLAVKEVNDYITRLTTRNQQITIKGITTHFTKQPYGWKDLDIASFIIKLFKGQEIKLQLNSSNLTTSERDLVNYITKRDYVERVVVKKRERISPALMKVVKDLSKEVFEVTALPDDEDGLMNRFKELLVSEKNKINVLLVQYRNTFYPGQDVLQDGKESIEQLLNISDTTSFYNKVKQLQNDFLDYAEDVEPVKAFFETQRDIYDDAVKRLNIFEKNQTYVTDQKVTGFIESISKIVKHKEPYKNIHQLPGLIKEFDELFVELLEKECEPVKNVIESDYQTVLEELNKHEEIKSMFFNKFKNSFDGIKDRLNRVNNFYEAIAMQTESDRLKVRCIDDIANEVERRKPPVTSPCTGTTCTTVIDPIVEYKAKKKTISKNTILRGTKTIENEEDIEAVLDEIRKQLQKELEDASVIKLV
What is the function of this protein?
BREX systems (bacteriophage exclusion) provide immunity against bacteriophage.  A core protein of a type 1 BREX system.  This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA.  Methylation of bacterial DNA by PglX probably guides self/non-self discrimination.  When the brxA-brxB-brxC-pglX and pglZ-brxL operons are transformed into a susceptible B. subtilis strain (BEST7003) they confer resistance to bacteriophages SPbeta, SP16, Zeta, phi3T and SP02 and partial protection to phages SP01 and SP82G (these include lytic and temperate phage).  They do not protect against phages phi105, rho10 or rho14.  Additionally confers a very slight reduction in efficiency of plasmid transformation.
What are the official names of this protein?
Probable ATP-binding protein BrxC, BREX protein BrxC.
What is the protein family that this protein belongs to?
Belongs to the BrxC family.
Protein: CNOT4_HUMAN
Sequence: MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPYPEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQTSSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQQHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIPVAGEEEVKVSTMPLSTSSHSLQQGQQPTSLHTTVA
What is the function of this protein?
Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins (PubMed:11823428, PubMed:22159038, PubMed:26575292).  Involved in activation of the JAK/STAT pathway (PubMed:11823428, PubMed:22159038).  Catalyzes ubiquitination of methylated RBM15 (PubMed:26575292).  Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA (PubMed:29861391).  As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy (PubMed:29861391).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, E3 ubiquitin-protein ligase CNOT4, Potential transcriptional repressor NOT4Hp, RING-type E3 ubiquitin transferase CNOT4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TMCA_PHOAA
Sequence: MLPELSAIQAEMQQQGLRRLLVLSGDHNWCHQQAHELQQEFMGDWLWISYRKEKAVLPEKAAGLLGQEYLHGVFDATEGLNAEALAILAGTLKAGSWLVMMVPSWHQWNDQPDRDSIRWNEQSGAIPTPNFIQHIQRQIANDRQVLLWRQNDPFYIPELPQYREWQLPDGQPTAHQHTILARLLRANQGVWVIIAPRGRGKSTLAGMLIQQWQGHCWLTAPAKATTEVVRCYSSEKGQFWAVDNLLKYCRQNSVSDIDWLLIDEAAAIPTPQLFELISYFPRILLTTTVQGYEGTGRGFLHKFCAEIPGCHILNLTEPMRWAESDPLENWLEEALLFDDAVPANHSAKAIGYHVYQQQQWIQQPELLKQFYGILTSAHYKTSPLDLRRLLDAKGMQFVAALGNNTLIGALWMVEEGGLSAELAHEIWAGRRRPRGNLVAQSLAAHSGLPQAAVLKSQRISRVAVQVNRRRQGIAQGMIAFQRERAEEQGMDFISVSFGYTAELWALWQKCGFQLVRIGTHLEASSGCYTAMAIFPLSQQGIALCVQAQQQLARDAYWLESQIGFSLPVDDQADQRLNQNDWQELAGFAFAHRPLSASLPALQRLLLNCGLPLTALRNHLQREMSIEQCVTELRLNGHKALTLLWRQETAQALVSLDEKLAMYWQEWTTVFSEANRLHHPICH
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_PSELT
Sequence: MVTQYIPLKEKYEKEVVPKLMKEFNYRNINQVPRIEKIVINMGIGEGSRNADLLNKHLKELAAITGQKPVITKAKKSISNFKIRKGMNVGLKVTLRGLRMWNFLYKIANIVLPKVRDFRGLNPNSFDGHGNYSFGLTEQFVFPEITPDQSPKTQGMDIVIVTTAKTDAEAFKLLEFLGFPFKR
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: AROB_STRPS
Sequence: MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y884_STAAS
Sequence: MILGLALIPSKSFQEAVDSYRKRYDKQYSRIKPHVTIKAPFEIEDGDLDSVIEQVRARINGIPAVEVHATKASSFKPTNNVIYFKVAKTDDLEELFNRFNGEDFYGEAEHVFVPHFTIAQGLSSQEFEDIFGQVALAGVDHKEIIDELTLLRFDDDEDKWKVIETFKLA
What are the official names of this protein?
Putative phosphoesterase SAS0884.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: PRS4A_ARATH
Sequence: MGQGPSGGLNRQGDRKPDGGDKKEKKFEPAAPPARVGRKQRKQKGPEAAARLPTVTPSTKCKLRLLKLERIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYADIGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSKMTLSEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHPDFKKAKEKVMFKKKEGVPEGLYM
What is the function of this protein?
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (PubMed:22158466) (Probable).  Interacts with transit peptides of proteins targeted to the chloroplast, and may be involved in the degradation of unimported plastid protein precursors (PubMed:24846764).  Is required for the maintenance of postembryonic root and shoot meristems (PubMed:15073153, PubMed:21784786).  Has a specific role in the regulation of organs size (PubMed:19500299, PubMed:19321709).  Acts redundantly with RPT2B in the regulation of gametogenesis (PubMed:21784786, PubMed:22158466).  With RPT2B plays a critical role in 26S proteasome assembly (PubMed:22158466).  Acts as an upstream signaling component for inducing both defense and morphological phenotypes in the constitutive active uni-1D mutant (PubMed:21791544).  Acts as negative regulator of endoreduplication in trichome cells (PubMed:20195883).  May function after the completion of the third endoreduplication step (8C to 16C) mediated by RHL1 (PubMed:20195883).  Acts as negative regulator of transcriptional gene silencing (TGS) at specific endogenous genes through DNA methylation (PubMed:22615900).  Promotes post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS (PubMed:22615900).  Involved in tolerance to zinc deficiency, possibly through alleviation of oxidative stresses or processing of poly-ubiquitinated proteins (PubMed:21389614).  Required for resistance to the fungal pathogen Golovinomyces cichoracearum (PubMed:22577987).
What are the official names of this protein?
26S proteasome regulatory subunit 4 homolog A, 26S proteasome AAA-ATPase subunit RPT2a, 26S proteasome subunit 4 homolog A, Protein HALTED ROOT, Regulatory particle triple-A ATPase subunit 2a.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus. Note=Localizes to siRNA-bodies in the cytoplasm.
Protein: VOPP1_RAT
Sequence: MARPLGRVAALLLGLLMECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMNPVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK
What is the function of this protein?
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
What are the official names of this protein?
Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, ECop.
What is the protein family that this protein belongs to?
Belongs to the VOPP1/ECOP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Protein: FBXL8_HUMAN
Sequence: MAEPGEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCECELEGMLPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPLFDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVGSVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQPAVPVAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAALEELAARCAALREVHCFCVVSHSVLDAFRAHCPRLRTYTLKLTREPHPWRPTLVA
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box/LRR-repeat protein 8, F-box and leucine-rich repeat protein 8, F-box protein FBL8.
Protein: PMM_YEAST
Sequence: MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLAKLRNKCCIGFVGGSDLSKQLEQLGPNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKDGFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions such as folding and glycosylation of secretory proteins in the ER lumen.
What are the official names of this protein?
Phosphomannomutase, PMM, Asparagine-linked glycosylation protein 4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SYNE7
Sequence: MGIRAFRPYTPGTRERVVSDYAEITRNEPEKSLLVSKHRRKGRNNRGVITCRHRGGGHKRLYRIIDFKRDKRNVPGKIVSIEYDPNRNARISLVYYEDGEKRYILTPAGVHVGTPIIAGDETPIEVGNAMPLQNIPLGTTVHNVELVAGKGGQIVRAAGASAQVVAKEGNYVALKLPSTEVRLVRKECYATIGAVGNAEVRNTSLGKAGRKRWLGRRPEVRGSVMNPVDHPHGGGEGRAPIGRSGPVTPWGKPALGRKTRKKNKQSDRLIQRRRRKSSKRGRGGRDA
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL15_BLOPB
Sequence: MYLNTISPSRGSKHLSKRVGRGIGSGLGKTGGRGHKGQKSRSGGKVRLGFEGGQTPLYRRLPKFGFISRKAMVTQEIRLSDLSRVSDKVIDLNVLKTYNIISRKIKFVKIIMSGEIKRPITIRKLRVSKGARAAIQSIGGQIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ACS1_CANGA
Sequence: MSPSAIAEKKQVDNIQEIKDKNQEPAHHEYEHLTNVGVVKQKPIDHRLKDNIKTHYSPHLDGLQEYKRQYQESIENPEKFFSEKARSFMNWFRDFDRVFVPDVDNPTKPSFENNAWFLNGQLNTCYNCVDRHALKTPNKTAIIYEADEPGEGYSMSYKELLEKVCQVAQILKYSMNVKKGDTVAVYMPMIPEALITLLAISRIGAIHSVVFAGFSSNSLRDRINDAGSRVVITADESNRGGKIIETKRIVDDALRETPQVEHVLVYRRTNNPQVNFQAPRDLDWETERKKYKTYFPCEPVDSEHPLFLLYTSGSTGTPKGVQHSTAGYLLGALLTMRYTFDVHQEDVFFTAGDIGWITGHTYCVYGPLLYGCTTLVFEGTPAYPNFSRYWEIIDKHQVTQFYVAPTALRLLKRAGDSFIDGFSLKSLRCLGSVGEPIAAEVWEWYSDKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASLPFFGIETVILDPTTGEEINDSHAEGVLAIKRPWPSFARTIWKNHDRFLDTYLNPYKGYYFTGDGAARDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDRMVAECAVVGFNDDLTGQAVAAFVVLKDKSTWASASEEELQDIKKHLILTVRKDIGPFAAPKLIVLVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGVVKHLIDSVKL
What are the official names of this protein?
Acetyl-coenzyme A synthetase 1, Acetate--CoA ligase 1, Acyl-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: CT5B_CONVR
Sequence: MRCVPVFIILLLLIPSAPSAAVQPKTEKDDVPLASFHDSAMRILSRQCCPTIPECCRVG
What are the official names of this protein?
Conotoxin ViVB, Vi5.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: 36012_ASFWA
Sequence: MLPSLQSLTKKVLAGQCVPTNQHYLLKCYDLWWHDGPITFDHNLKLIKSAGIKEGLDLNTALVKAVRENNYNLIKLFAEWGANINYGLVSVNTEHTRDLCRELGAKETLNEEEILQIFIDLKFHKTSSNIILCHEVFSNNPILQKVNNIKMRIEIFWELRELIEKTDLLNNEFSLSALLLKYWYAIAIRYNLKEAIQYFYQKYTHLNTWRLTCALCFNNVFDLHEAYEKDKIHMDIEEMMRIACIKDHNLSTMYYCYVLGANINQAMLTSIQYYNIENMFFCMDLGADAFEEGTIALGEGYKLIKNILSLKIYSPATTPLPKSTDPEIIDHALKNYVSKNMMIFLTYDLR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-12L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: MYOM1_BOVIN
Sequence: QSMSTLHQEEAFEKADQLSLKKTLEETEAFHKKLNEDHLLHAPEPVIKPGTAYKNQVPINVQAHPGKYIIESRYGVHTLEINDDTRFHSGASTLPPSXYASRFEIHFQPEIQXYRNGVPIDAEXXGAPAIPKYNDYIIITXKQPAVDGGSPILGYFIDVGIGXPSRVSEPVAALDPAEKARLKSRPSAPXTGQIIVTEEEPSEEAGTENXQRVNTELPVKXSNNAGVXEPEETGGAEITGYYVNYREVIDGVPGRXREANIKAISDEAYKXEEXTIAVPGPPHMTFKNRARVVGGLPDVVTIQEGKLLASDEHXNLKYGSEISDFTVSVFIPEEEARSVA
What is the function of this protein?
Major component of the vertebrate myofibrillar M band.  Binds myosin, titin, and light meromyosin.  This binding is dose dependent.
What are the official names of this protein?
Myomesin-1, 190 kDa titin-associated protein, Myomesin family member 1.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: MATP_YERPS
Sequence: MKYQQLENLESGWKWAYLVKKHREGEAITRHIENSAAQDAVEQLMKLENEPVKVQEWIDAHMNVNLATRMKQTIRARRKRHFNAEHQHTRKKSIDLEFLVWQRLAVLARRRGNTLSDTVVQLIEDAERKEKYASQMSSLKQDLKDILDKEV
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLC2F_MOUSE
Sequence: MNAQCLKKPEEGESSPGTGDKILQRNSLRAISPESSAKLYCCCGVIMVLTVAVVALSVALPATKTEQILINKTYAACPKNWIGVGNKCFYFSEYTSNWTFAQTFCMAQEAQLARFDNEKELNFLKRHMNSSHWIGLHRDSSEHPWRWTDNTEYNNTFLIQGDGECGFLSDNGISSSRDYIPRKWICSRSSNYMLQC
What is the function of this protein?
Lectin-type cell surface receptor.
What are the official names of this protein?
C-type lectin domain family 2 member F, C-type lectin-related protein C, Clr-c.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NS12_CVBF
Sequence: MDIWRPEIKYLRYTNGFNVSELEDACFKFNYKFPKVGYCRVPSHAWCRNQGSFCATLTLYGKSKHYDKYFGVITGFTAFANTVEEAVNKLVFLAVDFITWRRQELNVYG
What are the official names of this protein?
Non-structural protein of 12.7 kDa, ns12.7, 12.7 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.
Protein: IF2_PORGI
Sequence: MSIKLFSLAKELNVGVGSLAGFLRKKGFDVEDNNPNVRIENEEFDLLLTEFGKSLPKGEAERIRKKFVKQKQGTPASAPSAKEETAGMAAKEAQVIATEVPQDMRPRFTIKGKVETEKPAEPVPSPKDKEPDTVREDKPARETAPVKEETKVVPVKEDKPKEEKPKQEEPKREEPKPEEPVQAAPVAKPVEKPVDKPQQPVMTQKPQEAETPPPAQEMEKKEDTEEVFRLKTNTQEPQVKVVGKIDLSSINSSTRPKKKTKEDRQREQNDADGKKKRKRINKAAVDVKKEAAKVSGEQGKRNAGGGNHSSGNKNNNRPAQQQSNASGGRKNNKRQSLPPKVEISDEDVQRQVKETLARLTTKKTSTTLGRGAKYRKDKRDAASRAAQDAMELNSEEQHTLKLTEFVTVSDLSNMMDVPVNEVIATCMSIGMMVGINQRLDAETINIVAEEFGFKTEFVSADLVEAIAPEEDNEEDLVARPPIVTVMGHVDHGKTSLLDRIRNTNVIEGEAGGITQHIGAYGLKLPSGRRITFLDTPGHEAFTAMRARGAKITDIAIIIVAADDDVMPQTVEAINHASAAGVPMVFAINKIDKPAANPERIKEQLANMNYLVEDWGGKYQSQEISAKKGINITELLEKVLLEADILELKANPNRRAIGSIIESSLDKGRGYVSTVMVQNGTLNMGDVVLAGTCHGRIKAMFNERNQRVKQAGPSEPVLILGLNGAPAAGDTFNVLETEQEAREIANRREQLQREQGLRTHKILTLEDISRRRAIGNFQELNLIVKGDVDGSVEALSDSLIRLSTEEIQVNVIHKAVGQISESDVVLAAASSAIIIGFQVRPSVAARKQAETDGVEIRTYSIIYDTIEDIKSAMEGMLSPEIREEVTGSLEVLQTFKISKVGTIAGCMVKEGKVKRTSKVRLIRDGIVIHTGELGSLKRFKDDAKEVVAGLECGLNLAHSNDIQDGDIIEAFDEIEIKKTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_MYCAV
Sequence: MAVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGPDHRVGADVERTGRGGRQGGGRRAPRASQEWAGPGVVAGPGGRRARRAAGPARAAGLGRGGHRRPGPRRGVDRRRRPAAGKHPVRRPRNVQGRRRAARAGRQMAELVGPTGAFVSDGFGVVHRKQASVYDVATLLPHYAGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGKSLVETEMVDTCRRLLDTYVDVLRLPVDMVAADRLAADAAPQTVPADAIPDDLMGVDIGPGSVKRFTALLSNAETMFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSVVGGGDSAAATAVELQLLFPLVRLIARLA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_LBVAV
Sequence: MSLKSAPYLSEISVSNGDSGIGFDGGCADPYAPSRVPSRRWDYSTKWDMKITGAAREFNLSKQPVLTGLINSMRMKTSLTHPEIHVVWRGLVPPAVCRDDVVVTLRFTPDRSEKMGLIAQHTHGMHLYMHHVFYPSHSIRVGPGEPLPWAVGFSVPDFSLDPNYTIAEVHVRLTGYFSELPEYDIQRDSELISIVPMEEHVTGYATSAPRIPNTAWVARGYKIGVNGNSLAKKIKFLQEIGVDIEALRMVGQLDNTLKKVSPRAIDGSPSAEAKSEAARLVNAHVKTLTA
What are the official names of this protein?
Protein 3.
Protein: Y807_RICCN
Sequence: MHRLAKIISNAGVCSRRDAEKLIVAGQVKVDGITILSPTTNVDISNQIEVSGTLINNIHKPRLWIYYKPVGLITTHKDPLSRKTVFEQLTGLPRVISIGRLDLNSEGLLLLTNSGDLARQFELPSSRLKRVYHVRAYGKSDILLKSNYKNLEIDGIFYNPHSIKLLKQNKTNCWFEVVLFEGKNREIRRIFEYCGLKVNKLIRIQYGSFTIDNLKPGDYKEINNKILENN
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase RC0807, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: KLOT_MOUSE
Sequence: MLARAPPRRPPRLVLLRLLLLHLLLLALRARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRRMTDYNIRECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKNNFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKEDPMKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK
What is the function of this protein?
The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.
What are the official names of this protein?
Klotho.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Note=Isoform 1 shedding leads to a soluble peptide. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Klotho peptide]: Secreted.