PharMolix/UniProtQA huggingface dataset:
Protein: HIF1A_HUMAN
Sequence: MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
What is the function of this protein?
(Microbial infection) Upon infection by human coronavirus SARS-CoV-2, is required for induction of glycolysis in monocytes and the consequent pro-inflammatory state (PubMed:32697943).  In monocytes, induces expression of ACE2 and cytokines such as IL1B, TNF, IL6, and interferons (PubMed:32697943).  Promotes human coronavirus SARS-CoV-2 replication and monocyte inflammatory response (PubMed:32697943).
What are the official names of this protein?
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with HIF3A in the nucleus and speckles (By similarity). Cytoplasmic in normoxia, nuclear translocation in response to hypoxia (PubMed:9822602).
Protein: RL32_STAAS
Sequence: MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEVAAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CRCM1_CHICK
Sequence: MSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDAEHDYPRGLLIAFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKKNPLDPAENSNSSITSGQAAAIASTSIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNELAEFAWLQDQLDHRGDAISPAVTHFA
What is the function of this protein?
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores.
What are the official names of this protein?
Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A.
What is the protein family that this protein belongs to?
Belongs to the Orai family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPRT_YERPB
Sequence: MSTLRIPIALQQAVMQCLRHYLQLANQHLGTAYPEPKINYHQRGTNAGSAYLQSFEIRLNPVLLLENKQPFIDEVVPHELAHLLVYRQFDRVAPHGKEWRWMMEQVLKVPASRTHQFEVASVRSKTFNYQCKCQQHALTIRRHNKVLRGESEYRCRQCGEKLQFITINPD
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_BACPU
Sequence: MNHRLSALVNGGFLSENEANKLMHDMMSGFLTDAEVAASLSILAHRGETAEEMTGFVKAMRQNAAPMERALDVVDTCGTGGDGLSTFNISTAAAIVRSAAGAKIAKHGNRSVSSKSGSADVLECLGIHIQSTPEETRRQIQEKNMGFLFAPLYHSSMKQVAAVRKQLGFRTVFNLLGPLCHPMQAKKQIIGVYSKEKAKLMAEALAPLEPEHVLFVCGEDGLDELTITANSYVIELKKDVMTEYTLNPEDFGLQKGYLSEIQVQSPEESAKLIQNILNHQTEGAPLHITALNAGAALYVAGKSESLMAGTLKAIETIKNGAAKEQLARLKQKTREEEIYA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SUMT_YEAST
Sequence: MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIHSILNAGGNPIVVNPSSPSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVDRVFVDLPITQSRLCEEIFWQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVTTNGNGYILANRIKRDIISHLPPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSLPGFGYGLDEDGWESHKFNKLIREFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLEDFETSSSPNKKTKQETVTEGVVPPTDENIENGTKQLQLSEVKKEEGPKKLGKISLVGSGPGSVSMLTIGALQEIKSADIILADKLVPQAILDLIPPKTETFIAKKFPGNAERAQQELLAKGLESLDNGLKVVRLKQGDPYIFGRGGEEFNFFKDHGYIPVVLPGISSSLACTVLAQIPATQRDIADQVLICTGTGRKGALPIIPEFVESRTTVFLMALHRANVLITGLLKHGWDGDVPAAIVERGSCPDQRVTRTLLKWVPEVVEEIGSRPPGVLVVGKAVNALVEKDLINFDESRKFVIDEGFREFEVDVDSLFKLY
What is the function of this protein?
Siroheme synthase involved in methionine biosynthesis.
What are the official names of this protein?
Uroporphyrinogen-III C-methyltransferase, Urogen III methylase, SUMT, Uroporphyrinogen III methylase, UROM.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: VIRB7_BRUA2
Sequence: MKKVILAFVATAFLAGCTTTGPAVVPVLDGKPRVPVNKSVPAKPPLAQPNPVDTYED
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system putative lipoprotein virB7.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NADK_CLOAB
Sequence: MKNIGVNINSCKDPDGTIRKYVEKVIKEEKKDVQVKFYDELNYFDEVCKTKPDFFIAFGGDGTILNAARNLVSCGIPIFSVNIGHLGFLSSIEFKDFKDAIHKIFKGEYFFQERTMLKCSFIKGNSKKVFYSLNEVVLYKGNMAKILKYNIDVDDKFYMGFKSDGIIISTPTGSTAYNLSAGGPIIYPNLDLISLTPICPQGPYAGTIVLDGKSNITISGIDANENVFITVDGRQPVDVKGVSFIEISKLNYKCKLLKLKDYNYFEVLRKKIILRTEECEGDKY
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_AQUAE
Sequence: MKLHEHQAKEIFAKYGIPVPEGKVAFSLKEAKEVAEELGEFPLVVKAQIHCGGRGKAGGVKIVKDMDELEKAVESLLGKVLKTFQCPDGKPVNRVLIEKATNIDKEYYLAITLDRSKSKPVIMASAAGGMEIEEIVKENPEAIIIETIDPELGLMPYQARELAFKLNLPVKEFASIALKLYQIYSDLDASLVEINPLVLTKEGNLIALDAKLDIDDNALFRHKDLEEMEDETQLPQLEVEAKKYGLNYIKLNGNIGCMVNGAGLAMATMDIIKLAGGEPANFLDVGGGANVEQIANAFRILMADPDVKAVFINIFGGILRVDRLAQGLIEASKMVELRVPIVARLEGTNVEEGKRMLQESGLNFIIAEDMWDGAKKAVEIANKQS
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ATP6_MAMPR
Sequence: MNEELSAFFDVPVGTMMLAIAFPAILLPTPNRLITNRWITIQQWLVKLIMKQLLSIHNTKGLSWSLMLITLTLFIGLTNLLGLLPYSFAPTAQLTVNLSMAIPLWTGTVILGFRYKTKISLAHLLPQGTPTFLIPMIIIIETISLLIRPVTLAVRLTANITAGHLLIHLTGTAALTLLSIHSMTITVTFITVVVLTILELAVALIQAYVFALLISLYLHESA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NIFD_ACIFI
Sequence: MSISAEDLSTQPQRRKLPEIAELIDETLKAYPEKFAKRRAKHLNVYEEGKSECDVKSNIKSVPGVMTIRGCAYAGSYGVVWSPVKDMIHISHGPVGCGHYARAGRRAYYIGTTGVDTYTTMHFTSDFQEKDIVFGGDKKLAKLMDELEELFPMSKGITVQSECPIGLIGDDIEAVSKKKAAEFGKPVVPNRCEGFRGVSQSLGHHIANDSIRDWVLDPAADKHPDFESTPYDVTLLGDYNIGGDWGSRIILEEMGLRVIAQWSGDAPSRSSTASSKSKLNLLHCYRSVNYITRHMEEKYGIPYIEFNFFGPTKIKESLRQIAAFFDESIQEKAEKAIAKYQPQWDAVVEKFRPRLEGKKVMLFVGGLRPGHTIGAFEDLGMEVIGTGYEFGHNDDYQRTTHEIKGNTLIYDDVTGYEFEKFAEKLRPDLVASGVKEKYIFQKMGFPFRQMHSWDYSGPYHGPDGFAIFARDMDMAVNNPVWGLTQAPWK
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: NLTP1_LENCU
Sequence: MASLRVSCLVALMCMVVISAPMAEAAISCGTVSGALVPCLTYLKGGPGPSPQCCGGVKRLNGAARTTIDRRAACNCLKSSAGSISGLKPGNVATLPGKCGVRLPYTISTSTNCNTIRF
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 1, LTP1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: SPE2D_STRPU
Sequence: MAANLLFSEDQIKEYKTKFDAFDRNNDGNFPTMFLGNAMKSVGHVLTAAELENSRRVRKGTTTFPQFLAMILDKKCRKVFKAMDKDDKDKLLSADEVRQAMLSFDRQITEDKIKEMIEKADFPNDGKCSLEEFVKMVMNFC
What is the function of this protein?
Calcium-binding protein involved in larval development and metamorphosis.  Likely to function as calcium buffers mediating the transport of calcium from the sea water to the blastocoel where calcium is required for skeleton formation.
What are the official names of this protein?
Calcium-binding protein SPEC 2D.
Protein: ADM5_HUMAN
Sequence: MTIHILILLLLLAFSAQGDLDTAARRGQHQVPQHRGHVCYLGVCRTHRLAEIIYWIRCLHQGALGEGQPRAPGPLQLWAPPVARGGSPARFPGFRPAARGLAQCPARWVTSGTARPLLGFSLPICMLELLLHISSPLTPAPETVFPSPSPGCD
What is the function of this protein?
Probable non-functional remnant of adrenomedullin-5.
What are the official names of this protein?
Putative adrenomedullin-5-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: WASC2_DROME
Sequence: MDISADVDQIIAQAPDWTFAGDCALLALMKRISQNLEERGERTSRNLRDFETSVKQVDIALNNATTSLRSLQFGNQFVEYRVEEVDDADLAMPEEKKKKPELPLKSSEELAKEFLENNLRMFRKNYEPVTIEVPDSDDEDGPVHSTTVFRAKNPYDAIPLPYIIGTKEWQEHKYAGLYDSKENSEDDRSEEFSSSSSDEKEPETKKIATPANKLEEQHLSDSSSLASFAREPAIVSPVINPAVQVAEPVIRTQPRPIINSQRNPHERDMFAALRQSPPSDDPPSTSSSPTSSPAFRNPSSRLPIVSTASLSSSSSSPAQQPPRLFDEAVSTQTPKEAEIKPSQTKRMPVNLFNEDEFKSFMSEIVDKVQSKTPSSSVSPATTISTKEPPKTKKPVEEYPKPGPPKQIVEQTVPKRVNLFDDSPPLSPTPRSEPVFNNTKATGAIPKRSPVVVANNDEDNSLFGSSPAMPKENPSKKPPKPVTKSLFDDDLEDDDFLSSFTPKAKPPEQKLLSKPKPSLFDDDDLDIDDIFTKPSAQPKKLSERVAGKTSLFEDDDQDDVTDLFGSKKAKVIPKETSSGVSPNKNVETPVASKKSLFDDIEDEDLFGTPKAKNLIRSEPDNDPEAVGEDKKQSEIAEQKSKNIETGEKQHQVIAENASVPILRDSPPPMEVTEQKSDDKEWEAVKDDTSAANITKSKDLFSEDLTDDELFSSTSNNMAEPKSANETNEFNKPIEKYTSQTEENVSPVNPPTKLSIKPTDLFNEDFSDDDTFLSASMSKNEPLVGTENEDIKKPSEVQLVKEIKAEELPQQLPENKIYEITAVVEKDELVPEMLSKPQIDEPVSETPPPDDYQSNVDPIISMVADVTNKTSVDTLTPRKPADLAAAQQIMQNYSNLFSDEPPDDSEFFQTLGSSGLSSLSASKIFDNEHDFFEPALPNIPSATKPSPVTPGDQPSVSSDYGAMCLFSDVPPEDNDHAGEEVQKEAEPQKDELASTTRIHTIFYDDFSETARAGAVQPAPKRFPFDDEPPPADETDRSEVKETPELQKPTSPVKKLKMPNININVHALLPGSGSVPKLIRKQESSSSERDEPQATVQTEAEAPSSGQNTVSSADGVLQHVNKSRARGPAKRRPSTRRGRKENYAKSLLDAGQNEGPTASTRDSPEVEHSERSSIKAPSPQYVKPEKLFSTPAQQIQPQLQRPPPSNTGGSFLDSPDEDDSFFNSVPTKTVEGKQGTDPPKSYRSFLDSPDADDKLFSDLENNKAGINVVPVEKKPPKMANSFLASPDEDDFLFDSVKTNATTTAQKAFAAEIMNAFQKVTTAPPKPSNAKEAAKPKSQAAPKLFDDSDDDDDDLFARAPSIQTASKPVQAKQPPKPAATSLFSSDDEEAEVPVKSAPAKKLPVKPSKSLFSDDDDDDDLFGGSSTSKAAAAKKTKPAARTASKPPASKTTTPTATIPSNSGDNPLADLLDFK
What is the function of this protein?
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting.
What are the official names of this protein?
WASH complex subunit 2, Family with sequence similarity 21.
What is the protein family that this protein belongs to?
Belongs to the FAM21 family.
Protein: GMDS_HUMAN
Sequence: MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVHADVELMRTNPNA
What is the function of this protein?
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
What are the official names of this protein?
GDP-mannose 4,6 dehydratase, GDP-D-mannose dehydratase, GMD.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: THIC_THEYD
Sequence: MTRIEMAKKGIITEEVRQVAQEEGVFPEELSQNIAEGRVVITRNILRNIKPLGIGKGLRTKINANIGTSRDKTDIQEELEKLDIAVKYGADAVMDLSTGGPLTEMRRAILKHSSVSIGTVPIYEVAVRAIEKYGNIVKMTVDDIFNVIEEHAKDGVDFVTVHCGVTKKIVEMLKSGDRVLPIVSRGGSILADWICYHDKENPLYEYFDRLLELAKKYDLTLSLGDGLRPGCLADATDRYQLIELITIGKLKDIAISEGVQCIIEGPGHLPLNHVETNIKLQKSICKEAPFYVLGPLVTDCAMGYDHIAAAIGGALAGMYGADFLCYVTPSEHIRLPDKEDVKEGVIASRIAAHAADIAKGYAKAWQRDNKMAEARRNFDWQSQISLSFDPDKVHSMRSERPPLEDEKVCSMCGEFCAIKISRRAVE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NSP2_ROTPC
Sequence: MAELACFVSFSLTEDKVKWFPINKKAVKTMLCAKVEKDQRSNYYDTILYGVAPPPEFRNRFKTTERYGLDYESDQYSEVANLLADVLNMVSMPTEKFQFDIVKTVVQVRHLENLLLRIKDTDDILSENVKLRVKAVMIACNLVNETETTPLTESNEIVYQDSYFTITKLDYSSHKLLPLMADEYKITINTKTDIPDRDQTAFAAYIRYNFNKFAAISHGKRHWRLVLHSQLMSHAERLDRKIKSDKKHGRQFAYDDGDMAFVHPGWKACIGQLCGGTTFEVAKTSLYSVKTSKTVRTATNKIESDLISMVGN
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PAGP_ERWT9
Sequence: MRLKLILYFLILSCYLGIGSARAATLMHGVANTWNSFSDNVSQTWNDPQTFDLYVPAVTWHNRWTYDSDKIDKYNERPWGAGGGISHYDEKGNWNGIYLMAFKDSFNKWEPIGGYGWEKTWRPLADPDFHLGLGYTAGVTMRDNWNYIPIPVLLPLASIGYGSATFQMTYIPGTYNNGNVYFAWLRWQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: DTD_CLOBJ
Sequence: MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAM1_MOUSE
Sequence: MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate.  Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate.
What are the official names of this protein?
Phosphoglycerate mutase 1, BPG-dependent PGAM 1, Phosphoglycerate mutase isozyme B, PGAM-B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RS10_RHOBA
Sequence: MSTGPSEVIRIRMEAYDHAVLDQSARDIVDTVKATASIVHGPIPLPTRIERYTVLSSPFVNKKARQQYEIRTHKRLVDIVQASAKTIEALNKLSLPAGVDIKIKASAR
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FOCA_ECO57
Sequence: MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVFISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKASGRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHTFIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIPMGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRENDHH
What is the function of this protein?
Involved in the bidirectional transport of formate during mixed-acid fermentation (PubMed:19940917).  Functions to maintain relatively constant intracellular formate levels during growth, using different mechanisms for efflux and uptake of the anion (By similarity).  Is impermeable to water (PubMed:19940917).
What are the official names of this protein?
Formate channel FocA, Formate transporter FocA.
What is the protein family that this protein belongs to?
Belongs to the FNT transporter (TC 2.A.44) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEP3_HHV2H
Sequence: MGLAFSGARPCCCRHNVITTDGGEVVSLTAHEFDVVDIESEEEGNFYVPPDVRVVTRAPGPQYRRPSDPPSRHTRRRDPDVARPPATLTPPLSDSE
What is the function of this protein?
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes.  Participates also in viral entry at the fusion step probably by regulating the core fusion machinery.
What are the official names of this protein?
Cytoplasmic envelopment protein 3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 3 family.
What are the subcellular locations of this protein?
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid- anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: TRPA_PARMW
Sequence: MSSQMLSPIAQRFEQLKHEKRLALMPFLMAGDPDLATTSEVLLSLQNSGADMVELGMPYSDPLADGPVIQAAAARALAAGTTPGKVLEMLTSLKGQLTIPVILFTYSNPLLNVGMEAFCERAAAAGAAGLVVPDLPLEEAERLSPLAEQQGLDLVLLVAPTTPADRMVRIGQRSRGFTYLVSVTGVTGERAQMETRVEGLVEELKQSSAVPVAVGFGISGADQVRQVRSWGADGAIVGSALVKRMAAAGEGQIAEEAGQFCRELRNAAD
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: QUEC_CLOBL
Sequence: MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYLEFEKYLMN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.