PharMolix/UniProtQA huggingface dataset:
Protein: PSBL_NEOYE
Sequence: MSGPNPNKEPVDLNRTSLFWGLLLIFVLAVLFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MURQ_YERPP
Sequence: MSLGALISESRNPATMELDKLSTLAMLTCINDEDRKVPDAIRLVLPAVAQAVDLAADALKQGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDIALGMRDLQDLQLTATDMVVGLAASGRTPYVIGALRYARELGCPTAAISCNPDSPIAQEAQVAISPVVGPEALTGSTRMKSGTAQKLVLNMLSTGAMVKLGKVYQNLMVDVKATNVKLVDRACRIVVEATGVSRAEAEHALRQTDFEVKPAILMLLKGVSAEQARQDLRQHHGYLRAAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: DAPDH_ACET2
Sequence: MGGVTLEKIRIGIVGYGNLGKGAELGIRQNKDMELVGIFTRRNPNSIKPLTEGVKVYSVDSARDMADKIDVMLLCSGSRTDLPVQGPEFAAMFNIVDGFDTHNKIQEYFESVDAKAKESKKVAVIACGWDPGMFSLNRLFGEVILPEGKTYTFWGKGVSQGHSDAIRRVKGVVDAKQYTIPVESAIELVRKGENPELTTRQKHIRECFVVVEEGADKERIEREIKTMPDYFADYDTIVHFISLEELKEKHSGIPHGGFSIRTGRTGINNENKHTIEYSLKLDSNPDFTANTLLAYARAAYRLNKEGVFGAKTVFDIPPAYLSPKSAEELRRSLL
What is the function of this protein?
Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.  Probably plays a role in lysine biosynthesis.  Exhibits a high substrate specificity for meso-2,6-diaminopimelate (m-DAP), since the activity with L,L-2,6-diaminopimelate is less than 5% of the activity observed with m-DAP.  Can use NAD(+) only very poorly since the activity observed in the presence of NAD(+) is about 0. 3% of that with NADP(+).
What are the official names of this protein?
Meso-diaminopimelate D-dehydrogenase, DAPDH, Meso-DAP dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate dehydrogenase family.
Protein: ITIH4_BOVIN
Sequence: MKTPAPGRIHSIVLVLLSLAVLQTSKAQKVQNDIDIYSLTVDSKVSSRFAHTVITSRVVNKADAVREATFQMELPKKAFITNFSMVIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVSVSVAPAAKVTFELVYEELLARHLGAYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNKLAEALTTSQNKTKAHVRFKPTLSQQQKYPEKQDTVIDGSFIVRYDVDRPLSGGSIQIENGYFVHYFAPDSLSTIPKNVIFVIDKSGSMMGRKIKQTREALIKILDDLSPHDQFDLISFSSEATTWKPLLVPASTENVNEAKSYATGIQAQGGTNINDAMLMAVQLLEKANQEELLPEGSITLIILLTDGDPTVGETNPLNIQKNVRKAINGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLQDFYQEVANPLMTSVAFEYPSNAVESVTQDTFRVFFKGSELVVAGKLREQSPDVLLAQIRGQLHRENITYMMMSHVAEQEEMFRSPKYIFHSFIERLWAYLTIQQLLEQMVSALDAEKQALEARALSLSLSYSFVTPLTSMVITKPEGQEQSQVAEKPVEDESRGSRVYLGPMRFGHSVGDRTSRKPGGGLKLLNGTPLFGPPGPPAAASPFHRMTSRLVLPELMSPLAPASAPSPTSGPGGASHDTDFRIKGTTPTALPFAPVQAPSVILPLPGQSVDRLCVDLRRPQELVNLLSDPDQGVEVTGHFETAKARFSWIEVTFENPQVQIHASPEHVVMTRNRRNSAYKWKETLYSVMPGLKVTMDKEGLLLLSRPDRVTIGLLFWDGPGKGLRLLLQNTDRFSSHVSGTLGQFYQDVLWGPLDTADDSKRTLKVQGRDYSATRELKLDYQESPPGKEISCWSVEL
What is the function of this protein?
Type II acute-phase protein (APP) involved in inflammatory responses to trauma.  May also play a role in liver development or regeneration.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H4, ITI heavy chain H4, ITI-HC4, Inter-alpha-inhibitor heavy chain 4.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: BRNQL_STAES
Sequence: MNKNTWIIGFTLFAMFFGAGNLIFPTQLGLESGHFFWPAILAFALTGIGLPLLGVVVGALDKHGYIGSFNKISPRFSLIFLIIIYLTIGPLFAIPRTASTSFEMSVTPIAQNSGNLALFIFTVIYFLIVLYLCLNPNKMIDRIGSLLTPLLLITIVAMIIKGFVDFSGHSSNYGMTNAYHSNLSGFSQGFTQGYLTMDAIASIAFSMIVVNAIKTTGIQHADKIFKQTIIAGLIAAIALVFIYISLGYIGNHINIPSDTLKELKAKDQNIGTYLLTTMATKGFGTFGKYLLGIIVSLACLTTACGLIVSVSEYFHRILPKIPYKVFVIFFILVSFILANQGLNSVIKMSVPVLSVIYPVAITVILLILIARFIPTKRIAQQIPLIIVAIESILSLITTQGWIRISFIDDLPLKEYSLEWFPIAVVATLVGYMISYFVKQSNIVYQKE
What is the function of this protein?
Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine), which is coupled to a proton motive force.
What are the official names of this protein?
Putative branched-chain amino acid carrier protein SE_1090.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LYSW_SULAC
Sequence: MVLLKCPICGNDVNVPDDSLPGEIVEHECGAQLEVFNSNGKLALRLAEQVGEDWGE
What is the function of this protein?
Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha-aminoadipate (AAA) is sequentially converted to L-lysine.
What are the official names of this protein?
Alpha-aminoadipate/glutamate carrier protein LysW, AAA carrier protein LysW.
Protein: HTPG_MAGSA
Sequence: MAEEKRQFQAEVGKLLDIVVHSLYSNKEIFLRELISNASDSCDRLRYGAITEPDLLDGDSEFRIRLVPDKDAGTLTIIDNGQGMSHDELIANLGTIAKSGTSEFLARLTGDAKKDVSLIGQFGVGFYSAFMVAEEVTVTSRKAGEAKGWKWVSDGKGEFTVSPAEDAARGAAITLKLREGETEFLDAFRLKSIVKRYSDHIAIPVTLKDADKDEETINSASALWTRSKSEITPEQYKEFYHHVAHAFDEPWSTLHYKAEGAIEYTGLLFIPSSKPLDIFHPDRKQHVKLYVRRVFITDDCEELLPPYLRFVRGVVDSQDLPLNVSREMLQHNPVLSKIRTGLVKRILGELKKKSEDAEGKYDEFWAAFGPVLKEGIYEDFERKTDILELCRFRSTHGDGLTTLADYVARMKDGQDAIYTITGDDLDQLKKSPQLEGFAAKGVEVLLLTDPIDEFWVSAVRSYAEKDFRSVAAAGADLSKVKAPEGAEDKKADEAPADELTTLIEAVKLALGERVKDVRPSERLTESAVCLVAAEGEMSMHLEKMLRAHNQAPGERARILEINPRHALIKGLAARVKAGGTDAGLEDAAFLLLDQARIIEGEPPADPAAFARRMVSVMEKGLLG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_CENSY
Sequence: MSGPSIGVLSLQGDVRENIGMIHTAISRAGVGGSVEQVNDASAIKELDGLIIPGGESTVIGGLAGGELLDVIRTKVRGGMPAFGICAGLILLSKGATDRTVGRTGQPLLDLLDVRVERNAFGRQKESFETELSMTSCGIEEFRGVFIRAPVITEAGPGVQVIAEYDNKKVAVQQGSVLGVSFHPELTNDPSLHQYFLKMCA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: TFE_PYRAE
Sequence: MKDVYLYIVEKSVAWEFDSPEYGRLARKVAEMLYERKEDLTDDRIAILLNISTAETRRILQYLMRLNLVGVKKRTTEDYRIEYTWYVDDEIIKQAIGGRARTAREKISMLIRALTEGSYYICPNCHMRYSLDEAVNKGGVCPVCGAELEYVESLEEINKLTKVLQKLEKL
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: NU4M_ALBCA
Sequence: MTYLILLGASICLFPFWEVTMLTLAFIIPMSLTYLNINFTFSFSSELIWLTPIGTALIFLTLMVTLLVLIGTYNIKNYKYIGCLSSLNLVLMMAFCVCDFLTFYVMFEVSLIPTLLLILLWGYQPERMQAGFYLMLYTVTASLPLLLLLLYLYYTVGSLNFYIIMVYYSFNNNPLMLVGLMMAFLVKLPIYTCHLWLPKAHVEAPLGGSMVLAGVLLKLGGYGLYMLINFIISKSSSLVISVIITLSLWGAVIASIICIQQVDIKALVAYSSVAHMSLVSAGILMMSNWSYTCAKMTMIAHGYTSSALFVLANLSYLKIKSRSLMFMKGLLAIFPAMAFYWFLFSCMNMAAPPTLNFIGELLIIPSMYIASYMLLILMCIIMFISAGYSLYMYMTVNHGELGLYITPSIQLKNVDYHVLTAHLLPTFILLIPQLFSV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RNFH_BUCAT
Sequence: MKIIKVTVVYALPKIQYICQVDIALGSTVKDAILESNLLNLTNDVSFHHNRIGIYNKTVHLKFKIKDGDRIEIYRNLTIDPKEWRRNNVFLSKKLKKIY
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: AGUA_PSESM
Sequence: MTTLNSTPRADGFHMPAEWAPQTQVWMVWPERPDNWRLGGKPAQAAHVAIAKAIARFEPVTVAVSAAQYDNARARLDMPNIRVVEMSSNDAWVRDSGPTFVINDRGELRGVNWEFNAWGGFDGGLYAPWNLDSQVGSKVLEIERCPRYATQGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHLTREQIEAVLSDYLAVDKIIWLPDGLFNDETDGHVDNFCCYIRPGEVLLAWTDDPEDPNYPRCHAALSILENTRDAQGRAFIVHKMPIPGPLFATEEECAGVDQVHGSQERNPSVRLAGSYVNFLIVNGGIIAPSFDDPMDEKAREILQKLFPEHEVVMAPGRELLLGGGNIHCLTQQQPAPFKA
What is the function of this protein?
Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
What are the official names of this protein?
Agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: MHPD2_DECAR
Sequence: MTNNFMAPEAAAALLKAATADGRPIAPLRDRLAIADQDSAYAVQEINTRAWLAEGRRLVGRKIGLTSLAVQAQLGVDQPDFGMLFADMAVGDGEIVAAGRLIQPKVEAEVALILGRDLTQERHTYADLIRATEYALPSIEIVDSRIENWNIKFVDTVADNASSGLFVLGGRSVRLCDIDLTACAMEMKRGDEVVSRGNGRACLGSPLNAAIWLADVMVRCGRPLQAGDIVLTGALGPMVAVKSGERFDVSIEGLGNVSALFA
What is the function of this protein?
Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
What are the official names of this protein?
2-keto-4-pentenoate hydratase 2, 2-hydroxypentadienoic acid hydratase 2.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family. MhpD subfamily.
Protein: SYS_SORC5
Sequence: MLDPRHVAEHLDEVRAALALRSPAAAASLGDDFASTVSARRSNIQELERWQAERNAANEAMARLDKKSPEFAQKRDELKALSTRIKEAEQVVSELEKRMTELLSVVPNLPDPSVPVGAGEEGNVVVRAWGEKPSFSFAPKSHWDIGTALGLLDFERAAKLSGARFTVLMGAAARLERALISFMLDLHTREQGYLEVLPPFLVKDTALFGTGNLPKFAEDLFKTQKSDPERAYDLYLIPTAEVPVTNLHADEILDGASLPIAYAAYTPCFRSEAGSHGRDVRGLIRQHQFDKVELVRFSAPEDSARQHELLTSHAEEVLKRLGLHYRVSALCTGDLGFGSQKTYDLEVWLPGQGVYREISSCSNFGDFQARRAQIRYRPEPKAKPRLVHTMNGSALAVGRTVIAILEQYQQADGTVVVPEPLRAFMGCEVLRGR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_KORVE
Sequence: MKSVRVQPASNILGSVSFPGDKSISHRYGMLAALAEGTSRFKNFSTGADCASTLSCMEQLGAKVTHKDDGVIEVEGVAGQLRKSATQLDCGNSGSSMRMLSGILAAQPFDSELMGDASLSRRPMRRIVDPLKQMGGDIETTDGHAPLRVRGSKLTAIDYITPVPSAQVKSCVLFAGAFAAGITSVDEAIRTRDHGEIALKAFGAEVERRQNRVSVRGGAKFRAIEAVVPGDISSAAFFLCAAALFPTSNLVFDGILLNPSRAAILDVLASMGAKPKFLQVQEQHGELVGTITLAPAGLSGLKISGGLTASLIDELPVLAAIGAYTRYGIEIRDAKELRVKESDRIAVVCANLRAMGAEVEEFDDGLRVKGSQKLHGAEIESHEDHRIAMAFAVAALRAEGETVINGADCVAISYPEFFDTLNKVVER
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ALIFM
Sequence: MRIALCIEYDGAEYYGWQRQRDVNSVQEELEKALTIVANEPIEVHCAGRTDAGVHGTGQVVHFDTTSSRKLAAWMMGANANLPKNIAVRWAKEVNEDFHARFTATARRYRYIIYNNRLRPAILGHGVSHYHDALDANLMHEAGQYLLGENDFTSFRAVHCQSRSPWRNLMHLKVTRHGDFIVIDIKANAFVHHMVRNITGSLIEVGKGKQKPEWIKWLLEAKDRKLAGATAKAEGLYLVDVDYPLEWELPRVPLGPLFLDND
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: HIS31_PSEF5
Sequence: MKDWLDQIKWDADGLVPAIAQDHKTGRVLMMAWMNREALSLTAAENRAIYWSRSRGKLWRKGEESGHVQKLHEMRLDCDADVIILMVEQIGDIACHTGRHSCFYRVYEDGEWKTVEPVLKDPHAIYSAGH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase 1, PRA-CH 1.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNE1_CHLRE
Sequence: MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLSEKKKSSP
What is the function of this protein?
Endonuclease involved in group I intron homing.  Recognizes and cleaves a 19-24 bp palindromic DNA site.
What are the official names of this protein?
DNA endonuclease I-CreI, 23S rRNA intron protein.
What is the protein family that this protein belongs to?
Belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPC1B_DROME
Sequence: MKVIFATIWLIAGAWSQSAEQLGCIWYGQSHMIGAHWVNKGDTNPARPLNSPTSEAIFAKRCPMLYKEYKGESGEDELSLCCDAAQIETMESGLSQADGVFSRCPTCTRNMALTVCAMTCAKNHTLFLTAYNDTNDAGVDYVKYIDYRLTDDTVSKIYNSCIGIQHTQTGRPAMDLGCGSYNAKTCNYRRWYEFMGDVSGDYVPFQINYKWSEDAEEGSNEIYLDLSPLKCGESYEDSYACACIDCEESCPLTDAPTGPDELWKIAGLYGVTFILALIIACALSFFIFWGAFGKTSAPSVCMPTLFGEFFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNGVLNFGPAFEYNFLKEVFELQDSIMKLGMADNEGLDKICYAPVLMAGETPTVDRCAIQSVYGYFQHDMDRFENSYVDSNNYTINYLNQLEDCLRVPMMEDCFGTFGGPIEPGIAVGGMPKVAVGEDPDYMLATGLVLTFLGRNYNDESKLEPNMKWEKLFVDFLRDYKSDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVKSGGKKINDEDGDGVDRPKEVGLLETLFKNFYSPFLLSKPVKVSVLLIFTVITCLSLMVTPSIEKGLDQEMSMPKNSHVVKYFRYMVDLLAMGAPVYWVLKPGLNYSEPLQQNLICGGVECNNNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAISDCCKYNVTTGGFCSSNSKSEDCLPCERGFTENGLRPDAETFNKYIPYFLFDLPDAECAKAGRASYADAVIYTIDDVGMSTVQDSYFMQYSTTSTTSEEFYSQLREVRRISGEINAMFKENNVDAEIFAYCVFYIYYEQYLTIWGDAMFSLGMSLVAIFLVTLLITGLDITSTFIVLFMVICILINMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFKRAEGTAQERARHSLNVTGSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGPPQKLARSSGAEPTASITITTN
What is the function of this protein?
Important for cholesterol absorption at the midgut epithelium.  Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking.
What are the official names of this protein?
NPC intracellular cholesterol transporter 1 homolog 1b, Niemann-Pick type protein homolog 1b.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPZ_PSEAE
Sequence: MPSRLPAFRLLLVQLVVVLVAAISLWISWGPVAGYSGLLGGMIAWLPNCYFAYKAFRFSGARAAREIVRSFYAGEAGKLILTAVLFALAFAGVKPLMAPALFGVYLLTLMVSWCAPLLMGKTFTRP
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADEC_DESHD
Sequence: MNDRNLKKLAPKSLGREKAQLVLKNAQVINVFSEEILVRDVAVEDGVIVGVGQYQGREEVDLSGKYLCPGFIDAHLHLESTLVAPPELIHSALQWGTTTFIIDPHEVVNVAGEEGLDYMLEQTEGLAANVFLMLPSCVPAVPFEENGGVFSAEKMEPYLANPRVLGLGEVMDYVSVIEAEEGMVKKLRLFRERIKDGHAPYLQDKQLAAYALAGIKTDHECIDYAYALEEVRNGMQVLIREGSGARNLEAIVRGIRDNSMDTGNFSFCTDDKHINDIQREGHISYNIKKSIALGIPPLKAIKMATINTARCYNLTKLGAVAPGYQADFVILDSLEEVAVHAVYHKGKKVDREKKIEIKPCPEQLRRTVHLPNLSADDLKLAVPDSPSSLIQMIEGQITTKHVRDVLPAQDGCFVPNAQYNKVVVVERHKGTGHFAVAPVLGFNLRQGAIATSVSHDSHNVVAIGDNDESILLALQELQRVQGGYTMIRGQRVLATLPLPIMGLISDAGYQAVENTLNQMIGYAHEMGVPAHTHPFIALSFIALPVIPEIRITTRGLYDVVDQEFIR
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: PDXH_PSET1
Sequence: MKLEDIRREYLQNALSEDNLLDDPFKQFETWLEHAVASNLPDPTAMVVATVDDTGQPSQRIVLLKHLDNDGFVFFTNTGSRKAQELKGNNKISLHFPWHPMERQVIVYGEAKPLPTSAVAKYFLSRPKESQLAAWASAQSRPVSSRKVLMETFANMKNKFAKGEIPLPDFWGGYCVVPQKIEFWQGGAHRLHDRFMYQRQADNSWQITRLNP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YEJG_SHIFL
Sequence: MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVALKLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGVAIAEPFSNYNPF
What are the official names of this protein?
Uncharacterized protein YejG.
Protein: H3_PARLI
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTELRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y208_VIBCH
Sequence: MERLIEKLLYSSRWIMAPIYLGLSLLLLALGIKFFQEIFHLLPNIFTIKEVDLILVALSLIDVSLVGGLIVMVMFSGYENFVSKLDVDESEDKLGWLGKLDTSSLKNKVSASIVAISSIHLLKVFMNTENIESDKIKWYLLLHITFVVSAFAMGYLDKITKK
What are the official names of this protein?
UPF0114 protein VC_0208.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPIA_RUTMC
Sequence: MTQDEMKFAVAQAALKHVVKDTIIGVGTGSTTNFFIDALAKIKNEIKGAIASSKATRQRLESYDIKVFDLNEVETISVYIDGADESDDGLNLIKGGGGALMREKIVAAVANQFICIADESKLVTIMGDFPLPVEVIPMASNYVKYQISQRIGGTPTVRENFITDNGNLILDIKDLKITNPKVMETKLNSITGVVANGLFANRGADILLLGTSNGVKIVTRLIG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YEJM_ECO57
Sequence: MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWPTTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLLIDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKLRSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFLEKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFEKQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITALNQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNRWFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAGRGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTPASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDEKPQLSLLLQVLTDEKRFIAN
What are the official names of this protein?
Inner membrane protein YejM.
What is the protein family that this protein belongs to?
To H.influenzae HI_0842.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_SACEN
Sequence: MTDVQSLDEGVYEATAVLDNGAFGTRTVRFETGRLAKQAAGSVVAYLDDDTMLLSATTASKQPKEHFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPSFVDGLRNEVQVVVTVMSLDPQDPYDVLAINGASASTQLSGLPFSGPVGGTRMALIDGQWVAFPTYEQLERAVFDMVVAGRIVGDDVAIMMVEAEATEKTAGLVSAGAQAPTEEVVAAGLEAAKPFIRTLCQAQQQLAQAAGKATEEFPVFPAYADDAFTAVEQAASAELAEALKIASKQERENRLDEIKAAVLEKVGTGEGEQFEGREKEVGAAFRSLTKKLVRQRIIRDQVRIDGRGLTDIRSLSAEVGVIPRAHGSALFERGETQILGVSTLNMLRLEQTIDSLSPETTKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERALIPVLPTREEFPYALRQVSEALGSNGSTSMGSVCASTLSLLNAGVPLKAPVAGIAMGLVSDEIDGKTHYVALTDILGAEDAFGDMDFKVAGTKEFVTALQLDTKLDGIPSEVLAQALGQARDARFTILEVMAEAIGKPDEMSPHAPRVTSISIPVDKIGEVIGPKGKMINSITEETGAEITIEDDGTIYVGAADGPSAEAAIDKINAIANPQLPKVGERFLGTVVKTAAFGAFVSLLPGKDGLVHISKLGNGKRIGKVEDVVNVGDKLRVEIADIDSRGKISLVVVDDEAENADKGGESEETSEQGA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1514_METVS
Sequence: MREVMLSECMNLLYESNFVISKPFGRSCFDLIAKKADLKLLIKILKNIDSLSTEQSEELLNIARILQAVPLIIGSRTRNSVMEEGAVYERFGIKAVTFLTFQEQVRGIPPVVYANRGGFFVNIDGKALKETREKLNISVGELAEFSRVSRKTIYKYEQNEANPSAEVAIKIEEYLDVPLIKGINITDYFEGVNLPKSREEAFEKILKEGEDFKVKVIEILGDMGFNLLETTKAPFDAVAEESKNKGDEVHNVLFTNIQETENEEIRKKAIIVDEISKIFNSHSLLILETRKNEDKKIMSMSIRELEKMGDTVDLIDFIEKRKKSKDI
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein Mevan_1514.