PharMolix/UniProtQA huggingface dataset:
Protein: RS8_OENOB
Sequence: MTMSDPIADFLTRIRNANMVRHETVETPASKIKINIAQILKDEGFITDYQVVDTPNKQGLISLSLKYGPNRERIITGLKRISKPGLRSYVQADSVPKVLNGLGIAILSTSEGVMTDKAARAKMIGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FETP_ECO8A
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: INT3_HUMAN
Sequence: MELQKGKGAAAAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.  In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
What are the official names of this protein?
Integrator complex subunit 3, Int3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, SOSS-A, Sensor of ssDNA subunit A.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to nuclear foci following DNA damage.
Protein: TRHO_XYLFA
Sequence: MVIINTAAYHFVSITQPQTLADQIRAHGEIAGLKGTVLIANEGINLFLAGEKEAINAFYAWLCADVRFAALHVKYSVSAYKPFARFKVKVRPEIISFRRGDISPLQGRAPGVSAHTLRDWLRRGCDDNGRRLVMLDARNQQEIAYGTFSGAMTLPITKFTGFPGALAHYRDLLSDATVVSFCTGGIRCEKAVLWMRVDGMDNVLQLEGGILGYFEQVGGEGYDGRCFVFDKRVALDPQLRPLNDMRVVASFARSEIS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LIPB_XYLFA
Sequence: MDAVNACGAVAPSHVGRAALLRMLGAQPYVPVWHAMQRFTDVRDATAVDELWVVEHDPVFTLGQAGKLEHVLDPGEIPVVHVDRGGQVTYHGPGQLVVYPLLDLPRLGLGVRDYVYGIEQAVINTLAQWNILGERREHAPGVYVGGAKIAALGIRVRHGCSFHGVAFNVAMDLEPFHRIHPCGYRGLQVTSVLDLGGPSEMDTVAAALLAELARQFCFVLHPTSGWLSS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR89_ARATH
Sequence: MSKEGLIAAKELKRLQTQSVRLDRFIGSHVSRLLKSDLVSVLAEFQRQNQVFLCMKLYEVVRREIWYRPDMFFYRDMLMMLARNKKVDETKKVWEDLKKEEVLFDQHTFGDLVRGFLDNELPLEAMRLYGEMRESPDRPLSLPFRVILKGLVPYPELREKVKDDFLELFPGMIVYDPPEDICEDSDEEARTDSDLE
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g62350.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RNPA_YERPE
Sequence: MVKLAFPRELRLLTPSHFTFVFQQPQRAGTPQITILGRLNELGHPRIGLTVAKKHVKRAHERNRIKRLTRESFRLHQHALPSMDFVVLVKKGVADLDNRALTEALEKLWRRHCRQAPAS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: AROC_AFIC5
Sequence: MSFNTFGHMFRVTTFGESHGVALGCVVDGCPPRIPLTAAEIQRDLDRRKPGQSRFTTQRQEADQVKILSGVMETERGQVTTGTPIALMIENTDQRSKDYSDIKDKYRPGHADYTYEAKYGIRDYRGGGRSSARETAARVAAGAVARKVIPDVKVRAALVQMGPHKIDRANWNWDDVTRNPFFCPDATKAAFFEEYLDEIRKSGSSIGAVIEVVAENVPAGWGAPIYGKLDSDLAAALMSINAVKGVEIGAGFGAAELRGEDNADEMRAGNNGPVFLSNHAGGILGGISTGQAVVARFAVKPTSSILTPRKTVDRAGGETDILTKGRHDPCVGIRAVPVAEAMVACVLADHFLRHRGQNG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: REP1_ZYGBA
Sequence: MFSREEVRASRPTKEMKMIFDVLMTFPYFAVHVPSKNILITPKGTVEIPENYQNYPILAIFYVKYLMKKNPYDLLPSTVNWPEPYVVVNTITKRFQDHKLFANKNADVYVERLQNAIASGIKIPESKKNERLGQPKKTKNVTKEIEETFIDATNARKELDEYFRKLQDGTLTGDLEGGLCKVKTLISCKALFGGHTQELQFMATNVRKVWIGEIVCGMVSNKNAIDDNDLEEEERNASGEQTTTAREESEALDTTSNGLDALNTQINAIETEESFWEAIRALHNELRTSPTQLEECRKAAVFLLGHKKILQTFTKQKDTARALFYINLKECLGTSWNLEYTEASDARKMAIKGELQN
What is the function of this protein?
Plasmid partition require REP1, REP2, and a cis-acting DNA sequence (known as STB).  REP1 may act by intercalating in the yeast nuclear matrix and binding STB either directly or via REP2.
What are the official names of this protein?
Trans-acting factor B, REP1.
Protein: OPALI_BOVIN
Sequence: MSFSLNFTLPANTTSSPVVTSGKGADCGPSLGLAAGIPSLVATALLVALLLILIHRRRRSSESTEEIERPCEISEIYDNPRVAENPRRSPTHEKNIMGAEEAHIYVKTVSGSQEPMRDTYRPAVEMERRRGLWWLIPRLSLE
What is the function of this protein?
Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation.  Promotes oligodendrocyte terminal differentiation.
What are the official names of this protein?
Opalin, Oligodendrocytic myelin paranodal and inner loop protein, Transmembrane protein 10.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS. Enriched in the leading edge of extending processes.
Protein: INSY1_DANRE
Sequence: MSQSRAPAREPSETPSQREQIRSHMKMVIQQLEGILKELKDVAHELREVVGQIDKLTSDLELDLDADDWTVATASSTSSSERGLCEAFRLDFLGQDSLSDSWDFCSFLESSSRRSARDDTKPPPTTASVYSQMNGGLPVPNGPLIITPDSSSEEASSSTHSQSQKTSRTAGTRERVRFSDKILYHALCCDDDEDEDEDEDGRDEEEDKLDTDSERSPLAGSPVPPLPELYNCREPPAGGSHTIPRKDALNPGCRKKLLRNSSTQTVSDKSTQTLLPYVPAKHRNKDL
What is the function of this protein?
May be a component of the protein machinery at the inhibitory synapses, probably acting as a scaffold.
What are the official names of this protein?
Inhibitory synaptic factor 1, InSyn1.
What is the protein family that this protein belongs to?
Belongs to the INSYN1 family.
What are the subcellular locations of this protein?
Postsynaptic density.
Protein: PCKA_BACC7
Sequence: MSTVNVQIGLHELLNGSNAQIQLSVPQLVEKVLMRNEGKLTSTGAVSASTGKYTGRSPKDKFIVKEASVADKIAWGAVNQPISEEHFNKLYTKVLEYLKEKEELFVFKGFAGADRNYRLPIQVINEYAWHNLFVHQLFIRPTEEELTTHESEFTIVSAPNFKADPAVDGTNSEAFIMVSFEKRIVLIGGTEYAGEMKKSIFSIMNFLLPEQDILSMHCSANVGEEGDVALFFGLSGTGKTTLSADPNRKLIGDDEHGWSDNGVFNIEGGCYAKCVNLSHEKEPQIFDAITFGSVLENVIINDQTRIADYNDTTLTENTRAAYPMHAIDNIVLPSVAGHPNTIIFLTADASGVLPPISKLSKEQAMYHFLSGYTSKLAGTERGVTSPQATFSTCFGSPFLPLDASRYAEMLGEKIEKHDAKVFLVNTGWTGGEYGVGKRMNLGYTRAMIQAALSGELAKTETAKHDIFGLEVPLHVPGVPDEVLMPEQTWADKAAYKAKAIELANEFKANFKKFDSVSEDIINLGGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TABA_PSEAJ
Sequence: MPISESFARRLFPLLDELTNTYPTPFHIYDERAIVQTHRNVAQAFADSAFRQYFAVKALPTPAILSLLLKEGSGLDCSSPVELMLAERLGARGDDIVFTSNNTSLSEYQMALQAGALVTFDDRSMLEQVIALPDIVAFRVSPHGVIARSSQMGNAQQSKFGIPEAELVQSYREAWDRGARRFGIHGMMCANELSLEAAVQAGVQVIEVGARVAREAGIELEYINIGGGLGIPYRIDDQALDLTAYADALKRALKQAFPHNTPKLLMELGRYISGPHGVLVSRVINRCSKGREIVGLDASMSALMRPGLYGAYHHLTLPFADQRPEGVFDVVGALCENFDKFAVDRLLPSPLIGDLALIHDTGAHGHAMGFTYNGRLRPAELMLTDDGDVVEIRRAETFDDHTGPIQWQPVDVFNPTRCVK
What is the function of this protein?
Involved in tabtoxin production and pathogenicity.
What are the official names of this protein?
Protein TabA.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: FAU1_HALSA
Sequence: MTRVRVRGIYATALTQLLRNAGLDVVAASPPIRARFPDADLGAAEPHADIRMTPDRQGVGITAHGDDHARAVRAVVADLPRDTFVWPDPVPRGAVFDAAVDHTVGGGAILDLGDDREAYLPFGAVDDHVTDGDTLRVAIRDPAPPWHDDRPTATSTITVSGALASLDRGVDALVAGAATDRAELARATELLDPDIPDNWGVYWEYDGADASLDARGTALDTLAARADRLEATLADADGGDTPGLVAAPDTTLWAWFGRETRCALDDHRRTVAATMPGHHRIKAGSDAASDAVDFAEALGASVDEFPFGAVTDQFGPSVGASIEIQHGKPDGALISLGRGEVTDRSAENARITVEREMTGGGTYDALGVAREAGDTATTRFTEGNWWYPTVYRSEDGERKGTYLNVCTPVEVFPDAVRYVDLHVDVIKHADGAVEIVDREELQDCVADGLVSEELAEKALSVAERVQSAVAE
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: HDA_SALSV
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: AROB_STAAC
Sequence: MKLQTTYPSNNYPIYVEHGAIDHISTYIDQFDQSFILIDEHVNQYFADKFDDILSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFIAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLDFLKTLPFEQILSGYAEVYKHALLNGESATQDIEQHFKDREILQSLNGMDKYIAKGIETKLDIVIADEKEQGVRKFLNLGHTFGHAVEYYHKIPHGHAVMVGIIYQFIVANALFDSKHDINHYIQYLIQLGYPLDMITDLDFETLYQYMLSDKKNDKQGVQMVLIRQFGDIVVQHVDQLTLQHACEQLKTYFK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_THENN
Sequence: MRILLTNDDGINSKGIILLAEYLSKEHEVFVVAPDKERSATGHSITIHVPLWMKKVFISEDVVAYSTTGTPADCVKLGYNVIMEKRVDLVVSGINRGPNMGMDILYSGTVSGAMEGAMMNIPSIAISSASYESPDFEGAARFLISFLKEFDLSLLDPFTMLNINVPVGEIKGWKLTRQSRRRWNDYFEERISPFGEKYYWMMGEVIEDDDREDVDYRVVQQGYVSVTPIHPFLTNEGCLRKLREVYESCTE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CHLPD
Sequence: MRHKPTPPKGNKSLGNALASKKKVSKNQVVFFDYRDERKLKRFINDQGKIIPRRITGLSAKEQNLLTHSVKWARFLAVIPYVTDEYK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RPOA_CLOBH
Sequence: MLEIEKPKIECVENAEDGSYGKFVIEPLERGYGITLGNALRRILLSSLPGVAADHIKIDSVLHEFSTVQGVKEDVTELILNIKCLALTMNGEGPKTIYIDEVGPKEVTAADIKTDGDVEVINKDLHIATLDENGKMYMEINVNRGRGYVTQNKNKTKDMPIGSIAVDSIYTPVKRVNFSVENTRVGQITDYDKLTIEVWTNGTIRPEEAVSLSAKILIEHFKLFMTLTDHADDMEIMVEKEEDKKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELCERSMDDMMKVRNLGKKSLEEVEQKLEALGLGLRKSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LEXA_HAEI8
Sequence: MRPLTARQQEVLDLLKRHLETTGMPPTRAEISRELGFKSANAAEEHLKALSRKGAIEIIPGASRGIRILDNSSNDEFDGLPLVGRVAAGEPILAEQHIEATYRVDADMFKPQADFLLKVYGLSMKNVGILDGDLLAVHSTKDVRNGQIVVARIEDEVTVKRLEKKGSIIYLHAENEEFDPIVVNLEEQKNFEIEGIAVGIIRNNAWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NCAP_CVMJH
Sequence: MSFVPGQENAGSRSSSGNRAGNGILKKTTWADQTERGLNNQNRGRKNQPKQTATTQPNSGSVVPHYSWFSGITQFQKGKEFQFAQGQGVPIANGIPASQQKGYWYRHNRRSFKTPDGQQKQLLPRWYFYYLGTGPYAGAEYGDDIEGVVWVASQQAETRTSADIVERDPSSHEAIPTRFAPGTVLPQGFYVEGSGRSAPASRSGSRPQSRGPNNRARSSSNQRQPASTVKPDMAEEIAALVLAKLGKDAGQPKQVTKQSAKEVRQKILNKPRQKRTPNKQCPVQQCFGKRGPNQNFGGPEMLKLGTSDPQFPILAELAPTAGAFFFGSKLELVKKNSGGADGPTKDVYELQYSGAVRFDSTLPGFETIMKVLNENLNAYQNQDGGADVVSPKPQRKRGTKQKAQKDEVDNVSVAKPKSSVQRNVSRELTPEDRSLLAQILDDGVVPDGLEDDSNV
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: HSCA_SALTY
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQTRYPHLPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVEPQDVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: VM2P1_PROMU
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPNRAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSETYYSPDGRKITTKPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGETHLIEPLKLSGSEAHAVFKYENVEKEDEAPKMCGVTETNWESYEPIKKASKLVVTAEPLRYVELVIVADHGMVTKYNGDLDKIREWVHEMVNTVDEIYDYMYIDVILADLEIWTNEDLINVQPSAHHTLDSFGEWRERDLLKRKSHDNAQLLTATDFDGPTIGLAHVASMCDPKRSTGVVQDHSTINLRVAVTLAHEMGHNLGIHHDKGSCSCGGYACIMSPVISHDPSKYFSNCSYIQCWDFIRKHNPQCILNKPLRTDTVSTPVSGNELLEAGEDCDCGSPSNPCCDVGTCKLSPGAQCADGLCCDQCRFKKKGTICRIARGDWNDDRCTGQSADCPRNGLYG
What is the function of this protein?
Inhibits platelet aggregation.
What are the official names of this protein?
Zinc metalloproteinase/disintegrin PMMP-1.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_FRATM
Sequence: MASYSTNEFKGGLKVLIDGNPMVIVENEFVKPGKGQAFNRVKLKNLLNDRVVEKTFKSGESVEAADVEELTTVYSYFDGDSYVFMHPETFEQYMVSEEALGETKKWLKDQDEYQVILFNGQPISIIAANFVNLEIIETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQTGEIIKVDTRTSTYVSRVKD
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_ALIB4
Sequence: MDIITGSMTALITPFKNGKVDLQKYESLIKRQIAQGINAVSPVGTTGESATLSHKEHKECIEVAVATCKNSGVKVLAGAGSNATHEACDIAKFAQEVGADGILSIAPYYNKPTQEGLYQHYKAIANSVELPLMLYNVPGRTGVDLLPETAIRLFDDVKNIYGIKEATGSLERATSLMSARKDFVVVSGDDSVDFPMLASGARGIISVTSNLLPNLKSKLVSSVLEGDYKTSLSIHNDLYELNKTLFCESNPIPIKAAMYLSGLLDSLEFRLPLTNPSAETMQKLEKILIKYEVIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_STRKA
Sequence: MAATFRGTTPVPPDARPRLTVLSGPSGVGKSTVVAHLRTVHPEVWLSVSATTRKPRPGEQHGVQYFFVDDEEFDKLVANGELLEWAEFAGNRYGTPRKAVLDRLEAGEPVLLEIDLQGARQVRESMADAHLVFLAPPSWEELVRRLTGRGTEAPEIIERRLAAAKVELAAETEFDVTLVNTSVEDVSRELLALMLRQSGERDISG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_ANASK
Sequence: MVKRGKKTKYLFVTGGVVSSLGKGLSAASIGALLENRGLEVQHLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTSAKMTRRNNYTTGRIYQNVIQRERRGEYLGKTVQVIPHITDEIKAVIREAAGGADILIVEVGGTVGDIESLPFLEAIRQMKYDVGEENAVYAHLTLVPFIAAAGELKTKPTQHSVKELREIGIQPDLLLCRSDRELPRDMKDKIALFCNVDPSAVFTALDVPSIYEVPLSLHREGLDDKLAELFNIWSRAPRLERWETIVDKVKNPRRGEVRIGIVGKYVELHESYKSLNEALVHGGIANDARVKLAFIDSTKLEEGDLSDLDKVDAILVPGGFGIRGTEGKILGVKYAREHKVPFFGICLGLQMAVIEMARNVLGLAGANSLEFDEATPHPVVTLMEGQKGVTDKGGTMRLGAYPCTLKEGTKARALYGAELVHERHRHRFEFNNDYRAQFEAAGMVFSGVNPDLGLVEMIELPGQHFVGCQFHPEFRSKPFAPHPLFAGFVKAALEHRDAQQRQPPAEVKKLAVGKNG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PYRD_SACMI
Sequence: MTASLTTKFLNNTYENPFMNASGVHCMTTEELDELADSKAGAFITKSATTLEREGNPKPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKKYPDAPAIFFSVAGMSIDENLNLLKKIQDSEFNGITELNLSCPNVPGKPQVAYDFELTKETLEKVFVFFKKPLGIKLPPYFDFAHFDIIAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNGFGGIGGEYVKPTALANVRAFYTRLRPDIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (fumarate), DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_CUPTR
Sequence: MSDILQKILAVKADEVAAARKRRDLPSLRAEAESLRSEAGLAPRGFERALRDKIAAGHAAVIAEIKKASPSKGVLREQFLPEAIAESYATHGAACLSVLTDEHFFQGHADYLKRARGACPLPALRKDFMVDLYQVYEARTWGADCILLIVAALDHGLMAELEACALELGMDVLVEVHGDDELEAALRLKTPLLGVNNRNLRTFEVSLDNTLDLLPHIPADKLVVTESGILAPADVKRMRDANVHAFLVGEAFMRAKEPGVELARLFG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LEUD_SULIM
Sequence: MIIEGPVIKFGDKIDTDIIIPARYLKYTDPQYLAQHAMEPLDPEFYKKASKGVIIVAGKVFGMGSSREQAAIALKAAGVKAVVAESFARIFYRNAINNGLPVITLPNSTKEIDENSYVKIDVETGEILVGNKVLKGKGITGMALEILQAGGIMEYLKKMQTVNRN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.