PharMolix/UniProtQA huggingface dataset:
Protein: KCC2D_HUMAN
Sequence: MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport.  Targets also transcription factors and signaling molecules to regulate heart function.  In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure.  Contributes to cardiac decompensation and heart failure by regulating SR Ca(2+) release via direct phosphorylation of RYR2 Ca(2+) channel on 'Ser-2808'.  In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program (PubMed:17179159).  Is essential for left ventricular remodeling responses to myocardial infarction.  In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC.  Regulates Ca(2+) influx to myocytes by binding and phosphorylating the L-type Ca(2+) channel subunit beta-2 CACNB2.  In addition to Ca(2+) channels, can target and regulate the cardiac sarcolemmal Na(+) channel Nav1. 5/SCN5A and the K+ channel Kv4. 3/KCND3, which contribute to arrhythmogenesis in heart failure.  Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca(2+) uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis (PubMed:16690701).  May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca(2+) transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.  In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit delta, CaMK-II subunit delta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RIMM_STRGC
Sequence: MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGNTLALFDKKDQFVMDVEIASHRKVKNFDIIKFKGMYHINAIEKFRDFSLKVAEEDLSDLEEGEFYYHEIIGLEVYENDVLLGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLGIDIEQGRVDVEIPEGLDDEN
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCT_SALA4
Sequence: MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASYFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: KTHY_DICNV
Sequence: MRGKFICLDGTEGSGKSSQIQAICSFLQQHGKTVITTREPGGTQIGEAIRELVLSPHYQPQALTELLLILAARHEHLQTVILPHLAAGTWVISDRFNDATYAYQGYGRGIDLKIIKTLEQIIQASFQPDLACILCLPEHIAAERVHNRAHDHDRIELENRAFFARVAQGYHARAQLPHARFIDASGDQNSVFQQIRHHLELLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NF2L1_MOUSE
Sequence: MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKELQDGREREDTWSGEGAEALARDLLVDGETGESFPAQFPADVSSIPEAVPSESESPALQNSLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLNGTANDTSGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSTLKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDEHGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK
What is the function of this protein?
Transcription factor that binds the extended kappa 3 site of the TNF-alpha promoter after Fc gamma RIII stimulation and participates in the induction of this cytokine (PubMed:9580677).
What are the official names of this protein?
Endoplasmic reticulum membrane sensor NFE2L1, Locus control region-factor 1, LCR-F1, Nuclear factor erythroid 2-related factor 1, NF-E2-related factor 1, NFE2-related factor 1, Nuclear factor, erythroid derived 2, like 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CNC subfamily.
What are the subcellular locations of this protein?
[Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Note=In normal conditions, probably has a single-pass type II membrane protein topology, with the DNA-binding domain facing the endoplasmic reticulum lumen (By similarity). Following cellular stress, it is rapidly and efficiently retrotranslocated to the cytosolic side of the membrane, a process dependent on p97/VCP, to have a single-pass type III membrane protein topology with the major part of the protein facing the cytosol (By similarity). Retrotranslocated proteins are normally rapidly degraded by the proteasome and active species do not accumulate (By similarity). However, retrotranslocated protein NFE2L1 escapes degradation and is cleaved at Leu-104 by DDI2, releasing the protein from the endoplasmic reticulum membrane and forming the transcription factor NRF1 that translocates into the nucleus (By similarity). SUBCELLULAR LOCATION: [Transcription factor NRF1]: Nucleus. Note=Translocates into the nucleus following cleavage of Endoplasmic reticulum membrane sensor NFE2L1 by aspartyl protease DDI2. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus.
Protein: YO046_YEAST
Sequence: MSESKFIFLIFNNDSMCKSEALSKELFSNAKFSKNNKFSNSDLAGFSLLAVSLSGNTIKDVALCITGLLAGDGILDTNGEIRDPFNGSRDADNVAVSVKFLVCLSEGGYAITGAFFFNSCKMSGLFTIISKDLLKMVNLTPSEFGDMGLYENACGDSLGTATRSERSSSLNVDENESTDEEACWYKHGGLESPTNGVFLEYEMSAGAAALTGYVIVFFVYDSLL
What are the official names of this protein?
Putative uncharacterized protein YOL046C.
Protein: RS2_RHILO
Sequence: MALPDFSMRQLLEAGIHFGHQTHRWNPKMAPYIYGARNNIHIIDLSQTVPLLHQALKQVSDTVAKGGRVLFVGTKRQASDIVADAAQRSAQYYVNSRWLGGMLTNWKTISNSIQRLRKLDEMLAGEAQGLTKKERLNLDREREKLDKALGGIKDMGSTPDLMFVIDTNKEAIAILEAKRLGIPVVAIIDSNCDPDKIDFPIPGNDDAARAIQLYCDLIAKAAIDGIARQQGALGVDIGASVEAPVEPALDPAPSTEAPQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PSF1_HUMAN
Sequence: MFCEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIPTIKFRHCSLLRNRRCTVAYLYDRLLRIRALRWEYGSVLPNALRFHMAAEEMEWFNNYKRSLATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHILS
What is the function of this protein?
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks (PubMed:17417653, PubMed:28414293).  GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built (PubMed:32453425, PubMed:34694004, PubMed:34700328, PubMed:35585232).
What are the official names of this protein?
DNA replication complex GINS protein PSF1, GINS complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
Protein: RR4_HELSJ
Sequence: MGRYRGPRLRIIRRLGDLPLFTKKKPHIASKRLPLGHPVRKIKRRPSIYGLRLLAKQRCCYSYGLRDYQLKNYIKKARNAQGDPIKNLIFLLESRLDSKIYRSGIVSTMAAARQLITHGHVLVDNIKITIPSYSCNESQILDYKNTKLTSELIEKIKLSFNPIYVLEYYAIKL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
Plastid 30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RL16_METNO
Sequence: MLQPKKTKFRKQFKGRIHGAAKGGTDLNFGSYGLKALEPERVTARQIEAARRAITREMKRQGRVWIRIFPDVPVTQKPTEVRMGSGKGSPEYWAARVHPGRVMFEIDGVAEDIAREALRLGAAKLPVRTRFIQRIVD
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TRM1_METHJ
Sequence: MDLTWVTEGRTTIAVPCQNPDVPFPPGTAPVFYNSRMALNRDSTVLVVRQTHPHSYLDAMAASGIRGCRVGYETGVPVTFNDRDQLAIDLITHNVQSLGIKADITCRDANSLMSDEKFGFVDLDPFGTPAPFIDAAIRSSGKYLGVTATDTAPLCGAHLKAGIRRYMARPLNTEYHTEVGLRILLGNVARHAAVYDKGITPLFCYAHEHFVRLHLQLKSSASAADKSIARLGYIHQCPKCPYRLEEQKFFPGIHTCPLCGASLTPTGPLWTGSTHDPNILAGMIEDAETFIAGDPSGLLKLLALCRDEPDISFSYDYHKLGKFYRLSPGPIDVLLNRLRDKGYRAGRVHYSGYGIKTDAPLEEIRDCISS
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: SYGB_SALTI
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAYVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNASVVDDVIDFMLGRFRAWYQDEGYSVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_CHASO
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLIISERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: COXX_RICRS
Sequence: MSSLVRPINLGKINNSQSTVKDYILLMKPRVMSLVIFTGFVGMWLAPYSVHPFIAGIAVVCIALGAGSAGAINMWYDRDIDSLMKRTQKRPIVRGVIESDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPAVKGTVYTKKQILIYSILLFIVSLMPFFIGMNNFIYLIISGILGVVFLYYAGSLFYDTPDNKQAKRFFAYSIFYLFFIFLLLYSTNTISTIS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCD_ACIB5
Sequence: MAIKSDRWIREMSEKHGMIEPYAENQVRFDKNGEKLISYGVSSYGYDVRCAREFKVFTNVHSAIVDPKNFDEKSFIDIESDVCIIPPNSFALARTIEYFRIPRNVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPARIYAGEGVAQMLFFESDEVCETSYKDRGGKYQGQTGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CA1A_CONMD
Sequence: DMCCHPACMNHFNC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin inhibits muscle nAChRs with moderate potency (IC(50)=11 uM on alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE (adult), and IC(50)=13 uM on alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND (fetal)).
What are the official names of this protein?
Alpha-conotoxin MilIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSPC_ECOLI
Sequence: MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLSIFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREMERYVTSDTFTLRSRFRQL
What is the function of this protein?
The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions.  PspC is involved in transcription regulation.
What are the official names of this protein?
Phage shock protein C.
What is the protein family that this protein belongs to?
Belongs to the phageshock PspC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TCT1_PHYPO
Sequence: MVHWEKHEGELSVVGVGAGSNDIWGVNHLGHIYHWDGHKWHKVDGELTNISVGHDGEVWGVNKNHNIYRLDRSNNKWTQIPGELVQVSVGSHHHVWGVNHLDHIYKWDHHHNKWDKIDGALTNVSVGKDGTVYGVNRGHQIYRWDGSKVDLVLGELVQIHVSDAEKIVGVNHLDHIYRLKHGKDWEKLDGELTWVSVGHHGEVWGVNKLHHIYKATL
What is the function of this protein?
Probably involved in bacterial recognition.  May be a lectin that function as part of a transmembrane signaling complex during phagocytosis.
What are the official names of this protein?
Tectonin-1, Tectonin I.
What is the protein family that this protein belongs to?
Belongs to the tectonin family.
What are the subcellular locations of this protein?
Cell surface. Cytoplasmic vesicle membrane. Note=Also bound to inner membrane of certain cytoplasmic vesicles.
Protein: FLAA_VIBPA
Sequence: MAINVNTNVSAMTAQRYLNHAAEGQQKSMERLSSGYKINSAKDDAAGLQISNRLNAQSRGLDMAVKNANDGISIAQVAEGAMNESTNILQRMRDLSLQSANGSNSKAERVAIQEEVTALNDELNRIAETTSFGGNKLLNGTYGTQSFQIGADSGEAVMLSMGSLRSDTSAMGGKSYSAEEGKDASWTVGDKTELKMSYTNKQGEEKELTIKAKQGDDIEQLATYINGQSEDVKASVGEDGKLQVFASTQKVNGEVEFSGNLAGEIGFGDAKDVTVKDIDVTTVAGSQEAVAVIDGALKSVDSQRASLGAFQNRFNHAISNLDNINENVNASNSRIKDTDYAKETTAMTKSQILQQASTSILAQAKQSPSAALSLLG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  FlaA is not essential for polar flagellar synthesis and swimming motility.  Homomer of FlaA is able to form a functional filament.
What are the official names of this protein?
Polar flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RECD_BUCAP
Sequence: MNMSHLLQNFANKKIITLVDFYFSQFISKKNSIIMLISACVSFESKNGHIFLPIEYFEKNCFFSISNKQFINKILKCLNKKKINWSLELSEHISCGDGSIITPLVFYKDKIYLYKIWKAEKKILERLYEKNQFDTIDTQQCLNILNNLFSKKKHDLQKIAVILTLINNIIFITGGPGTGKTTIILKIIIALIKNAKKKIKIQLSAPTGKATENLIEILNDKWLNRYLLKEEKKQFSFNPIMTIHQLLGISKKSEKIFFNKNNLLMIDILIIDEASMIDILMMSNILSALSKKTKIIFIGDHNQLKPVKSSSILKYICSYAEDGYSLKTQSILQEITQNSIINYKINKKNTSYISDKICVLKKSYRFEKKTGIYILSNAVYNKETKIFEKLFKNSIENVFFYEINSEIEYKKMINIIINNNKIFWRKIYEKKNIKEIIKTFKNHQILCIVKNGFFGVNFINKILEEEMYKRNIFNKRFYINNKLWYIGKPIIITENNQCLGIFNGEIGITNLSQKNTLQVSFLKKDNFIENIPIEILKNYKTSWSITVHKAQGSEFNNISLILPNKNLKILKKDILYTGITRTRKQLNIFSTKEIFIKTVLKN
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity.  When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity.  Negatively regulates the RecA-loading ability of RecBCD.
What are the official names of this protein?
RecBCD enzyme subunit RecD, Exonuclease V subunit RecD, ExoV subunit RecD, Helicase/nuclease RecBCD subunit RecD.
What is the protein family that this protein belongs to?
Belongs to the RecD family.
Protein: ATPF1_DESOH
Sequence: MRLFGMCESVKKKAAVIVVVSLMAFCCAGFAVAAEHGAEAAPKGWVATDTFRVMNFAVLAIALFLLLRKPVAGALNNRIAGIREELARLEAQKEEARKALEAYNERLKMLDKEAEKIIEDYKKQGEAAKARIMESAQASAAKLEEQARRNIDNEFESARQKLRLDIFEQAVARAEALVTEKITPDDQHRLVEEYLDKAVL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y6719_DICDI
Sequence: MAIGDKRKKNRKNKQNKKNKNDNELILLHNTNNKLINSNSLVNSNNKNNNNKNGNGGGVNVMVNQCYNVLNGSFLFGSFFNKFDVLFNYLKSFLTIQKQSLNVNKLTDSNITISQKDNITFSTNSNNNNNSTNGNSNSPSIIIQQQQQHHHFNESQSSNNNNNNGSSLSSLGGSYITVDDLNDQLKIVQLEQKIVNLEKEIQRMRNEQNQIHKQNLNQYHELLKQIINAASLIQQQPTSIIQQPPQPFVAPPPPPPPPPPMVFKPKPIVVQPVSTPSSSSNSLASKKSNGVPQFSISMADITGVKLRKTSSKFAQSNSSPSRVNGSPARNRVVTSPAGIKKSPFKRVLTPVKKSATTTTTSSSSNNATTTTAKGSTSTPLKDITNSNNIKNSVLSPKSITKPNTPSNIIFSPLSNNNNNASPYKPLTISTLR
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285869.
Protein: COBS_MYCA1
Sequence: MMRSLATAFAFGTVLPMPAGGRGPMGRGAMTALPVVGLALGALAAAVAWGGTVVFGRSSPLGGLLAVAALLLITRGLHIDGVADTADGLGCYGPPDRARAVMRDGSTGPFGVAAVVVVVMAQALAFSALAAGRPVPVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGAAVAGSQPATVAAAWVAVLLGMSLVAGPRPWHGPVAVLLGLGCGAVLVRHCVRRFGGISGDVLGAAIELTATVSAVALAALVRV
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS4_SHELP
Sequence: MARYLGPKLKLTRREGTDLFLKSGVRAIDSKCKLEAAPGQHGARKARLSEYGVQLREKQKVRRTYGVLEKQFRNYYKDAARLKGNTGENLLTLLETRLDNVVYRMGFGATRAEARQLVSHKSIMVNGRVVNIPSFKVSANDVISVREKSQKQARIKAALEVASQREKPTWVEVDAAKMEGAFKRLPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RRC1_ARATH
Sequence: MSSFSITRKKTPFQKHREEEEARKKKAEDETARLYQEFVESFQGDNATTKTFVRGGTINPGDKPKVDSEGEKSKDGGSVSKKGSRYVPSFLPPPLASKGKEPEKKREEERPREREKGKTRNIDNFMEELKREQEMRERRNQDRDRQGDSSPSSRFDELPDDFDPSGRPGSFDDGDPQTTNLYVGNLSPKVDENFLLRTFGRFGPIASVKIMWPRTDEEKRRQRNCGFVSFMNRADGQAAKDEMQGIIVYEYELKIGWGKAVSLPSQALPAPPPGHMAIRSKEGCNLVFSGQTGPPIITSVPNQNSELVLTPNVPDITVVTPEDEHLRHVIDTLALYVLDGECAFEQAIMERGRGNPLFKFMFELGSKEHTYYVWRLYSFAQGDTLQRWRTEPYIMITGSGRWIPPPLPVTRTQEHEKESASTYAAGRTRRAEVERTLTDPQRDEFEDMLRALTLERSQIKEAMGFALDNADAAGEVVEVLTESLTLKETSIPTKVARLMLVSDILHNSSARVKNASAYRTKFEATLPDIMESFNDLYRSITGRITAEALKERVLKVLQVWADWFLFSDAYIYGLRSTFLRSGVSGVTSFHSICGDAPEIENKSYADNMSDIGKINPDAALAIGKGAARQELMNLPIAELERRCRHNGLSLVGGRVMMVTRLLSLEDTEKQRGYEAVDEIPKHPQNHSTWEEVKSEREHIKNSYAEVEMKEPVNLPTTIPIPQPELKAFVGKEKNELILPASKWARDDDEADDEQKRSSSSGSDNTGGITFKADGEDLKGNDCVRAQPDNGMDEEQRQKRRRIEVALIEYRETLEEQGMKNPEEIERKVEINRKRLEVDYGLSGPNEGNRNQKSIIERKEKREDSQESSKKRHRGENKSQSPPRKSSTRERDHDLGRDRDRERHRDRDRQHDLNRDRDRREKSSSHDRDDNDRSKERDRDWRRRGTR
What is the function of this protein?
SR-like splicing factor required for phytochrome B (phyB) signal transduction and involved in phyB-dependent alternative splicing.
What are the official names of this protein?
Protein RRC1, Reduced red-light responses in cry1cry2 background 1.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: CAF1M_ARATH
Sequence: MFLIRLSRHNPSSFTLLTRRLHDQTISSSRLRDLYNFQSPPPLSSSASENPDFNQKNNNKKKPKPQYRPPSSLEGVKTVHSDLPFDFRFSYTESCSNVRPIGLREPKYSPFGPDRLDREWTGVCAPAVNPKVESVDGVEDPKLEEKRRKVREKIQGASLTEAERKFLVELCQRNKTKRQVNLGRDGLTHNMLNDVYNHWKHAEAVRVKCLGVPTLDMKNVIFHLEDKTFGQVVSKHSGTLVLYRGRNYDPKKRPKIPLMLWKPHEPVYPRLIKTTIDGLSIDETKAMRKKGLAVPALTKLAKNGYYGSLVPMVRDAFLVSELVRIDCLGLERKDYKKIGAKLRDLVPCILVTFDKEQVVIWRGKDYKPPKEDDEYSSFIHRESSIDSDVDLSCSRGAQDSPDETT
What is the function of this protein?
May be involved in the splicing of group IIB introns in mitochondria.
What are the official names of this protein?
CRS2-associated factor 1, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.