PharMolix/UniProtQA huggingface dataset:
Protein: RNY_BACAH
Sequence: MSSTVWILISILLATVGAVVGFFVRKSIAEAKINGAANEAKRILDEANREAEALKKEALLEAKDEIHTLRTEAELEIRDRRSELQKQENRLMQKEENLDRKDETLDKRELQLEKKEDSLVARQQQIEELESKVGELVQKQQTELERISNLTREQAKAIILGKVESEVSHEIAVMVKESEVRAKEEADKKAKEILSLAMQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEQTTFEVGVHGLHPDLIKILGRLKYRTSYGQNVLKHSMEVAYLTGLMAAELGEDEKLARRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINSIASHHGDTEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYEGVEKSFAIQAGREVRILVKPDTIDDLEAHRLARDIRKRIENELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COAA_RHOOB
Sequence: MARTSESSPYVEFDRKQWRTLRKSTPLVLTEEELYGLRGLGEQIDLEEVAEVYLPLSRLIHLQVAARQRLFAATATFLGEKHPDQQVPFVIGVAGSVAVGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPTAELNRRGIMHRKGFPESYDRRKLLRFVTEVKSGAEEVAAPVYSHISYDIIPGQYHLIRQPDILIIEGLNVLQTGPRLMVSDLFDFSIYVDARIEDIENWYIQRFLALRKTSFSDPDAHFHHYAGLSDRDATSAAQEIWHNINRPNLVENILPTRPRATLVLRKDANHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1553_MYCBO
Sequence: MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQINTVAAFVRNLTRAQNPLNLARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEELESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAAVTAAADLLEATARQTPGSTPSSSPGR
What are the official names of this protein?
Uncharacterized protein Mb1553c.
What is the protein family that this protein belongs to?
To M.leprae L518_C2_147 and M.tuberculosis Rv1524.
Protein: PTLA_BORPA
Sequence: MNPLKDLRASLPRLAFMAACTLLSATLPDLAQAGGGLQRVNHFMASIVVVLRGASVATVTIAIIWAGYKLLFRHADVLDVVRVVLAGLLIGASAEIARYLLT
What are the official names of this protein?
Type IV secretion system protein PtlA homolog.
What is the protein family that this protein belongs to?
Belongs to the PtlA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAPP_NOSS1
Sequence: MGSVLYSLSESANLYPASELFLRHRLQIVEELWESVLRQECGQNMVDLLRQLRDLCSPEGQATKDQAVSAVKLIEQLNINEAIRAARAFALYFQLINIIEQEYEQRQQLTRYSDLEAETAPLNGSENITSSSNHNEDDVIFNRGLGTDFLGKNWTNRGQGKQKGTFAALFPLLSKLNVPPQQIQRLISQLDVRLVFTAHPTEIVRHTIRDKQRQVVDLLQQLDEVENRAKDGGGYPWEAGEIREKLLEEIRLWWRTDELHQFKPTVLDEVDYALHYFQEVLFDGIPQLYKRFKYALNQTFSWLEPPSKDFCSFGSWVGSDRDGNPSVTPEITWQTACYQRKMVLERYIKSVTQLIELLSISMHWSDVLPDLLESLELDQSQLSEVYDALALRYRQEPYRLKLAYVLKRLENTRDRNLALYKGETPTNEDSPMYRSGSEFLAELRLIQHNLTETGLSCRELDNLICQVEIFDFNLTKLDIRQESTRHSDALNEILDYLQLLPQPYNDLSEEQRVAWLTTELQTRRPLISSELPFSDKTNDVIKTFRVVRSLQQEFGINICQTYIISMCRQVSDVLEVLLLAKEARLFDPAIAVGTIQVVPLFETVEDLQRSRSVMRQLFELPLYRALLAGGYKNTEVKVPNTELTPQSPAPSPQSVLTPDLQEVMLGYSDSNKDSGFLSSNWEIHKAQKSLQQIAEEYGVNLRIFHGRGGSVGRGGGPAHEAILAQPGHSINGRIKITEQGEVLASKYSLLDLALYNLETITTAVIQASLLRTGFDDIEPWNEIMEELAARSRQHYRGLIYEQPDFIDFFHQVTPIEEISQLQISSRPARRPSGKKDLSSLRAIPWVFSWTQTRFLLPSWYGVGTALQEFFNEEPEEHLKLMRYFYVKWPFFKMVISKVEMTLAKVDMQMAGHYVQELSDPEDKPRFEKVFEQIANEYYLTRDLVLKITDHGRLLDGDPVLQRSVQLRNGTIVPLGFIQVSLLKRLRQSKNNTATSGVIHSRYSKGELLRGALLTINGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: RLMN_STREM
Sequence: MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRIQSFDEMTNISKEFLAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDQRGQDERVSHVVVMGIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVSLHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQELADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGTDIDAACGQLRSNTMKKDRQKAAAART
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_GEOTN
Sequence: MTIRIVIAGPRGRMGREAVALVQRTDHFELAAVIDRRYDGQNLADIDGFAGIDAPIYTDAVRCFTEVKPDVLIDLTTPEVGKRHAELALRYGVRPVIGTTGFTPEDIERLTELAETNEIGAIIAPNFAVGAVLMMKFARMAAKYFTDVEIIELHHDQKLDAPSGTALKTAQLIAEVRPSKKQGHPDEKETLAGARGAAYDGIPIHSVRLPGFVAHQEVIFGGEGQTLTIRHDSLDRRSFMSGVKLAVETVMHLHTLVYGLEHILE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1631_PYRHO
Sequence: MEHWIVIYGGSESTKTLVCCNIYLNRIFSTSQYGNSADNVLYHTHYSSARPYYCYWNYSLFKFHYSCFKRGYSFGNIYKHWSAHGNLKGPCTYNSSLLKPRVLKHSAPPQVFWWGRRDLNPGLRRPRPGG
What are the official names of this protein?
Putative uncharacterized protein PH1631.
Protein: NFYA2_ARATH
Sequence: MAMQTVREGLFSAPQTSWWTAFGSQPLAPESLAGDSDSFAGVKVGSVGETGQRVDKQSNSATHLAFSLGDVKSPRLVPKPHGATFSMQSPCLELGFSQPPIYTKYPYGEQQYYGVVSAYGSQSRVMLPLNMETEDSTIYVNSKQYHGIIRRRQSRAKAAAVLDQKKLSSRCRKPYMHHSRHLHALRRPRGSGGRFLNTKSQNLENSGTNAKKGDGSMQIQSQPKPQQSNSQNSEVVHPENGTMNLSNGLNVSGSEVTSMNYFLSSPVHSLGGMVMPSKWIAAAAAMDNGCCNFKT
What is the function of this protein?
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).  Promotes the expression of heat stress-inducible genes by contributing to the formation of a heat stress-specific transcriptional complex with NF-Y subunits (e. g.  DPB3-1, NF-YA2 and NF-YB3) and DREB2A at the promoter of target genes, thus promoting heat tolerance (PubMed:25490919).
What are the official names of this protein?
Nuclear transcription factor Y subunit A-2, AtNF-YA-2, AtNF-YA2, Transcriptional activator HAP2B.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_BACC7
Sequence: MVAVIIKGNEVAEKKRAQLTEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLAEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y645_METJA
Sequence: MLRIPRSLKSIINTINGESGTRYIVRGLIDGSLSALGVVIGASGSADASVIIAAGLGGGIANGLSNILGAFTAEKASLERERIQKEKSLLKKNGYLKKSIIYKKAIRETMICGLIDGISTTIGSALPVVPFFLFDIKTALYVAIGITIAILFILGVFIGKISKENVIISGIKMVAGALAVAILCFMIEKAF
What are the official names of this protein?
Uncharacterized protein MJ0645.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_ENT38
Sequence: MQLNSTEISELIKQRIAQFSVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSPIEVIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTAMAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALSNTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAFPGDVFYLHSRLLERASRVNAEYVENFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNSGIRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDEATRKQLSHGQKVTELLKQKQYAPMSVAQQGLVLFAAERGYLEDVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKSILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PEAD_ECOLI
Sequence: MVTNLYQNMRANALADAELRRKAADELTCMTARINRGETIPEPVKQLPVMGGRPLNRAQALAKIAEIKAKFGLKGASV
What are the official names of this protein?
Putative protein PeaD.
What is the protein family that this protein belongs to?
Belongs to the phage P protein family.
Protein: NLE1_HUMAN
Sequence: MAAAVPDEAVARDVQRLLVQFQDEGGQLLGSPFDVPVDITPDRLQLVCNALLAQEDPLPLAFFVHDAEIVSSLGKTLESQAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR
What is the function of this protein?
Plays a role in regulating Notch activity.  Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity.  Required during embryogenesis for inner mass cell survival (By similarity).
What are the official names of this protein?
Notchless protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NLE1/RSA4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CLPS_NITEU
Sequence: MAADYRNPESIIEKGRARLNPPPLYKVILINDDFTPMDFVVKVLRHFFLMNEEMATKVMLKIHIEGAGICGIYPSDIAVTKVQQVNDFSRQNQHPLMCVMEKE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: Y5766_SORC5
Sequence: MSNGGDQQQHGLLGPDGAPGRVVVVTGLSGAGKSTALHALEDLGFFCVDNLPTSLVQPAVEACESGGITRIGLGIDVRVGSFLAGATAALDSIRTGRDVVILFLDASDETLLRRFSETRRPHPLTTGGSGAIAMLDGVLLERERLASLRARATIELDTTRLSTHDLRRVVIERLRPARVEVPRMSTRFVSFGYKYGIPLDADLLFDVRFLDNPYFVHGLRELTGNDEPVREYILKNPDALEFICRTEQLLSFCMPRYASEGKSYLTVGIGCTGGRHRSVVLTNALSDSLRRKTGLPITVVHRDVARVSTSGVPSGVGEGMAGAPGVDLRLAQPGATPSEPRPASDTSVTGGER
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein sce5766.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NUOI_BORA1
Sequence: MEAIKDFFGSLLLTELFKGMRLTGKYFFKRKMTLRYPTEKTPASPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIESDQREDGTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETHIHEYHGEKRGDLYFTKDMLLAVGDRYEADIAQRRAEDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DCD_CELJU
Sequence: MSIKSDKWMRRMVEQYGMIEPYEPGQVRYDAAGHKIVSYGTSSYGYDVRCADEFKIFTNVHSTVVDPKNFDEKSFVDIKSDVCIIPPNSFALARTVEYFRIPRSILTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQMLFFESDEICETSYRDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: AMPP2_VERA1
Sequence: MSDYETILKGKYPAKDHAKRVADHIRSKVPGANGILYLEGRHTKLEEDSDHPEPFRQRRYFFYLTGCILADCHYIFDLKTSQSTLFIPPVDPEDVIWSGMPMTAEEAKEKYDIDNVLYTNEVNAELARLGKGSGSTAFAIANQVLDTVSFIGFEDKNFDVLKGAIEECRVVKDDYEVALTRKANAISTTAHHAVMKAVNTAKNEQELEAIFLERCFAHGAKNQAYHAIHAAGRAAATLHYVHNSAPLDGKLNVLLDGGAEWDCYASDITRTFPISGKFSKESRAIYDIVLKMQLESIKVLKEGILWDDVHELAHKIAIEGLLDLGILKGEADEILKARTSVAFFPHGLGHYLGMDTHDVGGTPNYADSDPMFRYLRKRGTLPAGSLVTVEPGIYFCSFIIEPYLKDPTHSKYIDTDVLDKYWDVGGVRIEDNLLITKTGSENLTPTIKEPEEIEKFVGSS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase VDBG_02538, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: APC9_YEAST
Sequence: MNQNGDKNEGKLFQLPSLPPWKTPRFNKANFNNFTTPLRKRSTRVINDDSMPITGEVLEERTADDLYGINMDVDEVDYLNTLSHIEEEKQYDYSPFCERNTLRESRIDSFLKAERAAHCLVFHKVGHLDGIDSYRPDIDIMCGEEANKYDSANPEGNGSMLLESVPGCNKEDLERLSRREFVTNSKPNMRRLDDIINHETNALKSFWNDSGLVNSLQSHHLHEEYLLLQEELKNVYKIKCHDRVPIESLRDKCRRHYSNEDSSFL
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.  In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition.  In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
What are the official names of this protein?
Anaphase-promoting complex subunit 9.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPP_HAEDU
Sequence: MAVIPMVVEQTSKGERSYDIYSRLLKERIIFLNGEVEDHMANLIVAQLLFLEAEDPEKDIYLYINSPGGVVTAGLAIYDTMNFIKPDVATLCTGQACSMGAFLLSGGKKGKRFALPNARVMIHQPLGGARGQATDIQIQAQEILKLKEMLTRKMAEHSGQTFAKVAADTERDNFMSATEAKNYGLIDKVLTSRGEVA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAI_SALNS
Sequence: MRSVLTISASLLFGLALSSVAHANDHKILGVIAMPRNETNDLTLKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: SPS22_YEAST
Sequence: MNRITRKSCLFAIIFASLFVTHALGAAIDPPRRPHNVKPFHNGNLELQRRANEPFFEIDVKSLNTNSPISELCKKDLHVIESSHDLFHLQNQCEFILGSLKVTNYDSNILDLNSLRAIGGDLIIQDSPELIRIQAGNLNKIEGLFQLQGLTSLVSVEIPTLKFCQSLEWKVVPILNYVSMDSQNIEIIKDIVISDTSLANIENFNKVQEIDTFNINNNRFLETIHSNVKTIRGQFSVHANAKELELEMPHLREVENITIRDTSLVYLPQLTKVKSSLEFIENYFYELNLNNLQKIGGTLGIINNVNLIKVNLENLTDIQGGLMIADNESLEDITFLPNLKQIGGAIFFEGSFKDIMFDSLKLVKGSAFIKSSSNVLDCNKWTNPSNGRSIIRGGKFTCISGKKENTLNVKQDGTIIEKGYKDLTQEGEDSKKRVISKYANSANPSMQLDPLLFGTCLVAMLLF
What is the function of this protein?
Redundant with SPS2 for the organization of the beta-glucan layer of the spore wall.
What are the official names of this protein?
Sporulation-specific protein 22.
What is the protein family that this protein belongs to?
Belongs to the SPS2 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: TRUD_YERPG
Sequence: MDMENLTWLHGKPTASGILKANPEDFVVVEDLGFEPDGEGEHLLVRIRKNGCNTQFVADYLARFAKLHPRLVSYAGLKDRHAVTEQWFCLHLPGKEAPDLATFELEGCEVLEAVRHKRKLRIGSLKGNAFTLVLRHITDRQDVEQRLQQIAAQGVPNYFGSQRFGRGGNNLVQARLWANNEIRVKERSKRSFYLSASRSAMFNLISSYRLAQQLSTTVLEGDALQLSGRGSWFVAQADELAALQQRVTAGELNITAPLPGDSELGTHGEALAFEQACLAEQTELLSLIKRERVEGSRRAVLLKPQNMISNWWDDVTLELSFWLPAGSFATSVVREIMNQDRADDTDIIE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: BIOD_RHOPB
Sequence: MTPRIVVTGTDTDIGKTVFSAGLAGFLQASYWKPVQAGLDGGTDSSRVAALSGLPPQRILPERFRLNTPASPHLAAQIDGVRIELDALDVPQIAGSLVIEGAGGLMVPLNSDTLYIDVFARWNLPVVLCARTALGTINHALLSVEALRRRGIPICGIAFIGDDHRDSEDIICAIGQVRRLGRLPRLDPLDRHTLQAAFKTSFNREDFTS
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_METPB
Sequence: MPDAVGAIDQGTTSTRFIVFDRRGTIRAQAQREHEQIFPRPGWVEHDPREIWRNTHAVMREGLARAGLVPGDLAAIGLTNQRETALLWDRRTGEPLHNALVWQDTRTDRTVAALARDGGRDRFRAVTGLPLASYFSASKLAWLLDHVEGARAKAEDGTALFGTIDSWLVWNLTGGPDGGLHVTDVTNASRTQLMSLATLDWDEAMLGVFRIPRAVLPEIVSSSAVLGETRDPFPGVPVGGILGDQQAALFGQTCFAPGEAKNTYGTGCFALMNTGPEPVASTAGLVTTVAYRLDGRPPAYALEGSIAITGALVQWLRDNLGLIGASSEIEGLARSVEDNGGVYVVPAFSGLYAPHWRDDARGLIIGLTRYANKGHIARACLEATAYQTREVLEAMERDSGCPLSELRCDGGMTVNDLLMQFQADILDRPTLRPKVSETTALGAAYAAGLATGFWKTLEDLRDNWAVDKRWHPHIAAEERRALFAGWGRAVERSFGWVEENA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y1229_MYCTA
Sequence: MDGTPGHDDMPGQPAPSRGESLWAHAEGSISEDVILAGARERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDADPIDQPDYVAEGVRLLRSGGVIVVHRAALGGRAGDPGARDAEVIAVREAARLIAEDERLTPALVPLGDGVLAAVRD
What are the official names of this protein?
Putative O-methyltransferase MRA_1229.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: INKA2_BOVIN
Sequence: MDCYLRRLKQELMSMKEVGDGLQDQMNCMMGALQELKLLQVQTALEQLEISGGGPAPGSPESPWTQLEPPQWEGSRGPVRPGACSPSNQASLGSTSSGKFPSHRSVCGRELATPPRTPLPEPQPSAQQGPELAEPDDWTSTLMSRGRNRQPLVLGDNVFADLVGNWLDLPELEKGGEKGETGEAGEPKGGRGQPRELGRRFALTANIFRKFLRSVRPDRDRLLKEKPGWVTPTASEPRAGRSQKVKKRSHSKGSGHCPFPGASEPRRGENASTGCPKALESSPSGFDINTAVWV
What is the function of this protein?
Inhibitor of the serine/threonine-protein kinase PAK4.  Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.
What are the official names of this protein?
PAK4-inhibitor INKA2.
What is the protein family that this protein belongs to?
Belongs to the INKA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_BIFA0
Sequence: MIGMLKGRVESVDTSNAVVDVHGVGFELRMPSNDLTAMHMGQDVKIYTSMSVSQDAITLFGFLDARSKRMFLQLQKVSGVGPKVALSLLSTLAPDDLAQAIHDGDDKALSRAPGLGRKGAQKIILELKGSIDVDKIETGEPTSTQRIPTDKGVEQVVEGLMSLGWKQADAQQAVDSVISSSGIALPLEEGNVPTVLRLALTSLDRGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: INT11_DICDI
Sequence: MTIKVVPLGAGQDVGRSCVIVTIGNKNIMFDCGMHMGMNDARRFPDFSYISKNGQFTKVIDCVIITHFHLDHCGALPFFTEMCGYDGPIYMTLPTKAICPILLEDYRKITVEKKGETNFFTAQMIKDCMKKVIPVNLHQTIKVDEELSIKAYYAGHVLGAAMFYAKVGDESVVYTGDYNMTPDRHLGSAWIDQVKPDVLITETTYATTIRDSKRGRERDFLKRIHECVEKGGKVLIPVFALGRVQELCILIDSYWEQMNLGHIPIYFSAGLAEKANLYYKLFINWTNQKIKQTFVKRNMFDFKHIKPFQSHLVDAPGAMVLFATPGMLHAGASLEVFKKWAPNELNMTIIPGYCVVGTVGNKLLTTGSDQQQQSKPQSQMVEIDKKTTIEVKCKIHNLSFSAHADAKGILQLIKMSNPRNVILVHGEKEKMGFLSQKIIKEMGVNCYYPANGVTIIIDTMKSIPIDISLNLLKRQILDYSYQYNNNNLNNFNNFNNLNNLNNNNNNNNNNSLKLIDIKNNTSTLFINNNNNNKKKQQSVVVVEESEENQDNNLIEEESFISSNNLLKKARLPISTIPIQGLMVSKQDQSSSSSNSNQLKLLGMNEVSKELSIKEIEMQYSLNLNFNNNTSDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNISLNFEFLTNELQRLLPIGINIERLEDSFFKPISLKIKSVSIQHISNMNIVVKWLHKDENLATHIISILKSIN
What is the function of this protein?
Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  Mediates the snRNAs 3' cleavage (By similarity).
What are the official names of this protein?
Integrator complex subunit 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.