PharMolix/UniProtQA huggingface dataset:
Protein: ATL2_HUMAN
Sequence: MDGRWQCSCWAWFLLVLAVVAGDTVSTGSTDNSPTSNSLEGGTDATAFWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQPIYYGFSESAESQGLDGAGLMGFVPHNGSLYGQASSERLGLDNRLFGHPGLDMELGPSQGQETNEVCEQAGGGACEGPPRGKGFRDRNVTGTPLTGDKDDEEVDTHFASQEFFSANAISDQLLGAGSDLKDFTLNETVNSIFAQGAPRSSLAESFFVDYEENEGAGPYLLNGSYLELSSDRVANSSSEAPFPNVSTSLLTSAGNRTHKARTRPKARKQGVSPADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS
What are the official names of this protein?
ADAMTS-like protein 2, ADAMTSL-2.
What are the subcellular locations of this protein?
Secreted.
Protein: BFR_MYCTO
Sequence: MQGDPDVLRLLNEQLTSELTAINQYFLHSKMQDNWGFTELAAHTRAESFDEMRHAEEITDRILLLDGLPNYQRIGSLRIGQTLREQFEADLAIEYDVLNRLKPGIVMCREKQDTTSAVLLEKIVADEEEHIDYLETQLELMDKLGEELYSAQCVSRPPT
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: FIS_SALCH
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: Y342_CYAP4
Sequence: MIRTYTQRALAQAWLNRFRGHLPAFACILGFTQTGLIPGISAAGATPADRQYTAIADAEFLLNGPQPQPRYPLPPLTAGASPVLISHAVVSGLGLPVYLFNAGLPIPPAVSAIDLGGEPARCLSTGAALNLATVHHLLTQGLVWGETLADQHPYLLLGECVVGGTTTALAILTGLGYAAATKVNSSHPICNHAQKWEIVQQGLGRSPLKPSHPAPLDLVAAVGDPMQIVVAGMTIAASRKVGVLLAGGTQMLAVYALARAIACTEQLVWQPEAVVVGTTRWVAEDPTGDTVGLAEETDIPLLGSQLSFVRSRFPQLQAYEQGYVKEGVGAGGCAIAASLYRGWGQQELLTAIEAVGDRYSQVSAGSGG
What are the official names of this protein?
UPF0284 protein Cyan7425_0342.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: ECD_DICDI
Sequence: MNKAKNSGAVPQFVDNFEDFYNNGDDILNNKHKEEINFVKYRIFDTHLINYNNNNNNKNNNNNNNNNENTTITNKLNEIKEYLILNYIKDYIWQKEPFNLKIYDHKKKQQQQQQLPIHFYGNTKFEESIDDEWFIVYILLELTKKFQSLIVSIKDNDGEFILIETAQALPKWIKPTNSNNRVYLKNGEIHIIPLPSDPSQLDTIPYKMDTNTALSILSSSSNNIITKVSNEINEILKNRLKRFYNGEYFLKDQNQIKLAAIPIEIGYLLNQYPQLISDITTTFYNRDSDDMKTISTMKRFPMSRERDSFGNSGQLITTNIRFTRCLYAMLKLQQWNSPKNFHPQLPKPSHPTYDSRSLGVKIICGLEMVYNRSKRNSVSSYHRFNDDLNWLNYLKQLKSNNYFNDETIGSKLYKEKLLIAKNQYLKNNINNNNNNNNKEEESIYKLIDQVTNSKSVDEMIKILQESDKSKIESEDDWLNEENPDKFEDLITEFENDRQKQQQKQQQQQQQQQQNKEGKKEVKENNNNNNNNNNNNNNNNNNNNNNNNNNNNDSNLINDFSNQFKSMLSQLSSFDGVEFNEKSGNSKNKTKSSAYGNGGDDNISFDSNKFMDILKGFTDNNKYDDDYDDDDDDDDDMYQDIDNYEDSDDKDDDEDDENDEDDEDDGFEEYEDEDEDDDDEKEFQYVEFLKKSTIKQYMERMDQELNLKIIASSFELESTKLPKEFDDIEKSNNNNNNNINNNDKDVDEDDNENYKVNQKVDLNLNLVKNLLESLTEQQGFAGPASTLLKEMSDNNSKKREKKKTSSKKLIPKKGKVKENK
What is the function of this protein?
May act as a transcriptional activator.
What are the official names of this protein?
Protein ecdysoneless homolog.
What is the protein family that this protein belongs to?
Belongs to the ECD family.
Protein: IL2_BOSTR
Sequence: MYKIQLLSCIALTLALVANGAPTSSSTGNTMKEVKSLLLDLQLLLEKVKNPENLKHSRMHTFNFYVPKVNATELKHLKCLLEELKLLEEVLNLAPSKNLNPREIKDSMDNIKRIVLELQGSETRFTCEYDDVTVKAVEFLNKWITFCQSIYSTMT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_KAZHU
Sequence: MSTTKTIVVLPGDHVGTEITEEATKVLNAIAEKRPNIKFDFQHHLIGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGDVRPEQGLLKIRKELGLYANLRPCNFAFDSLLDMSPLKPEYARGTDFTVVRELVCGIYFGKRKEDTGDGVTWDSEQYSVPEVQRITRMAASLALQHNPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLSVQHQLIDSAAMILVKNPTKLNGLVITSNMFGDIISDEASVIPGSLGLLPSASLASPPDTNKAFGLYEPCHGSAPDLPKGKVNPVATILSVAMMLKLSLDMVEEGIAVEKAVRKVIDNGIRTADLRGTNSTTEVGDAIAAAVKEFL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BACHK
Sequence: MDKRISIAIDGPAAAGKSTVAKVVAKKLSYVYIDTGAMYRTITYAALEQKVDIENEEQLMEVVKNVKIEFQQGENTQLVFLNGQDVSEVIRTPEVTNRVSIVAKHRLVREEMVRRQQELAEKGGVVMDGRDIGTHVLPDAEVKIFMLASVEERAERRHLENMNKGFDSNLEQLKEEIAQRDKLDSEREVSPLKKADDALELDTTSLSIEEVVQKIMGIVSGVFAK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIL4_ECOLX
Sequence: MNTVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMFFPQLAMAAQGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFLAGFAIISVFIAVGMAVVGLK
What is the function of this protein?
Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established.  Mature pilin is assembled with the help of TraQ and TraX (By similarity).
What are the official names of this protein?
Pilin.
What is the protein family that this protein belongs to?
Belongs to the TraA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Secreted. Note=Propilin is directed to the inner membrane, where it is cleaved and acetylated. Mature pilin forms filaments that are secreted to form the conjugative pilus (By similarity).
Protein: MUTL_PROA2
Sequence: MPRITKLPESVANKISAGEVVQRPASVVKELIENAIDAGAGRIVLSIKDAGKQLVQIIDNGHGMSEPDALMCVERFATSKISSAEELETLGTLGFRGEALASISSVSHFELKSCSEGMDAAFLHRYEGGELVEKSKAAADRGTTISVRNLFFNVPARRKFLKTNATEFKHIFETVKAQALAYPEIQWQLFNDDEELFHFRSSDMHERLNFFFGEEFADSLIEIREENDFLSLYGYVGKPGMLKRQKNDQLFYINRRVIQNRMLSQALQQAYGELLVERQTPFALLFLGLDTRQVDINVHPAKLEVKFEDERNIRNMVYPIVKRAVQLQDFAPDVGIAGLLERQMTQDAMNPENSLRKLEYKRAAGPSSTTDDLYRSYLSELPPVSSPPPGSIGEQGEMFSDLLAPSRDRELKPSVYDRSALLQSDENRPDPAGSDSKIWQLHNKYIVCQIKTGLMVIDQHVAHERVLYERAVEIMNNNVPNSQQLLFPQKIELKSWEYEIFQEIRDDLCRLGFNLRSFGNRTVMIEGIAQDVRNGTEAVILQNMIDEYQQNALKLKLEKRENLAKSYSCRNAIMSGQKLSLEEMRSLIDRLFATRMPYVCPHGRPVIIKISLDQLDRMFGRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: KADA_METIG
Sequence: MKNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BACCQ
Sequence: MTKITVVGAGSWGTALAMVLADNGHDVRIWGNRSELMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNVVLLVVPTKAYREVLQDMKKYVAGPTTWIHASKGIEPGTSKRISEVIEEEIPEDLIKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNLLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEST_HUMAN
Sequence: MEGCMGEESFQMWELNRRLEAYLARVKALEEQNELLSAELGGLRAQSADTSWRAHADDELAALRALVDQRWREKHAAEVARDNLAEELEGVAGRCQQLRLARERTTEEVARNRRAVEAEKCARAWLSSQVAELERELEALRVAHEEERVGLNAQAACAPRCPAPPRGPPAPAPEVEELARRLGEAWRGAVRGYQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLLERRAALEQRLEGRWQERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQDPKLELQFPRTPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQARTPTLASTPIPPTPQAPSPAVDAEIRAQDAPLSLLQTQGGRKQAPEPLRAEARVAIPASVLPGPEEPGGQRQEASTGQSPEDHASLAPPLSPDHSSLEAKDGESGGSRVFSICRGEGEGQIWGLVEKETAIEGKVVSSLQQEIWEEEDLNRKEIQDSQVPLEKETLKSLGEEIQESLKTLENQSHETLERENQECPRSLEEDLETLKSLEKENKELLKDVEVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGTENQELVSSLQENLESLTALEKENQEPLRSPEVGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQSIVRPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPPEKVDLEPLKSLDQEIARPLENENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQAPLWTPEEINQGAMNPLEKEIQEPLESVEVNQETFRLLEEENQESLRSLGAWNLENLRSPEEVDKESQRNLEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAGVENEDEAELNLREQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQRGLVEGASVKGGAEGLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEVMLGSEPAMGESAAGAEPGPGQGVGGLGDPGHLTREEVMEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPREGREESEAEAPRGAEEAFPAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEGSQEASWGVQGRAEALGKVESEQEELGSGEIPEGPQEEGEESREESEEDELGETLPDSTPLGFYLRSPTSPRWDPTGEQRPPPQGETGKEGWDPAVLASEGLEAPPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLLLDPAAWDRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESDSVSVSVPWDDSLRGAVAGAPKTALETESQDSAEPSGSEEESDPVSLEREDKVPGPLEIPSGMEDAGPGADIIGVNGQGPNLEGKSQHVNGGVMNGLEQSEEVGQGMPLVSEGDRGSPFQEEEGSALKTSWAGAPVHLGQGQFLKFTQREGDRESWSSGED
What is the function of this protein?
Required for brain and eye development.  Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division.  Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
What are the official names of this protein?
Nestin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: XA1_XENLA
Sequence: MFFYVLLLALMAQGWSLPQGKTGEDSPVFRPPSPPMGPSLPPPVSHDLHRPSGHPEEFRTGASLPPKETPNEPRHGRPKRDLHHGKVVPTGVPHHTGEVLHHTDCSSNTHKSHEENRPKGFRTGRPLLPIKPEHGRHRRDLHHGKAVPTGVPHHTEKFHNGSNGKSHPPRPGHSTSAHNDNSSEEKRPKHGQEQGKKH
What are the official names of this protein?
Protein XA-1.
What are the subcellular locations of this protein?
Secreted.
Protein: YBED_SHIB3
Sequence: MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL
What are the official names of this protein?
UPF0250 protein YbeD.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: Y401_STAAW
Sequence: MEYIKKIALYMSVLLLIIFIGGCGNMKDEQKKEEQTNKTDSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGMWTIYTDFAKSNKADELSNEGMVLYLDRNTRTAKGHYFVKTFYEKDKFPDRKKYKVEMKNNKIILLDKVEDPKLKKRIENFKFFGQYANLKELKNYNNGDVSINENVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPVLKMHIDGNLKGSSVGYKKLEIDFSKGEKSDLSVIDSLNFQPAKVDEDER
What are the official names of this protein?
Uncharacterized lipoprotein MW0401.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PROF_CAPAN
Sequence: MSWQTYVDDHLMCEIEGNRLTSAAIIGQDGSVWAQSATFPQFKPEEITAIMNDFAEPGTLAPTGLYLGGTKYMVIQGEAGAVIRGKKGPGGITVKKTNQALIIGIYDEPMTPGQCNMIVERLGDYLIEQSL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Minor food allergen Cap a 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS8_VIBVY
Sequence: MSMQDPISDMLTRIRNGQAANKVAVKMPSSKLKVAIAALLKAEGYIVDFAVEGEAKPELEVTLKYFQAKPVIEQLKRVSRPGLRVYKKKDDLPSVMGGLGVAVVSTSKGLMSDRAARKAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HIS4_PSE14
Sequence: MLIIPAIDLKDGACVRLRQGRMEDSTVFSDDPVAMAAKWVDGGCRRLHLVDLNGAFEGQPVNGDVVTAIARRYPNLPIQIGGGIRSLETIEHYVKAGVSYVIIGTKAVKEPEFVAEACRAFPGKVIVGLDAKDGFVATDGWAEVSSVQVIDLAKRFEADGVSAIVYTDIAKDGMMQGCNIPFTAALAAATRIPVIASGGIHNLGDIQALLNAKAPGIIGAITGRAIYEGTLDVAEAQALCDREQR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_METBF
Sequence: MTKMMTPAMCQYYEAKQAYPDTLIFFRMGDFYESFGEDAKTIAKELEITLTARGKDKSGERMPLAGIPYHAIDTYLPRLINKGYKVAICEQLEDPKKAKGIVKRGVVRVVTPGTAIDSSMFSDASNNYLMAVAGREIGKPGKNAENEFEIGVSFLDISTGEFLTTQFRDSENFEKLLSELARMRPSECILPSSLYENPALAERLRAQTIVQEFAPDISGAKEAGERLKNHFRVATLEGMGCENLDFAVYSAWAALEYAQTTQMRELTHINTLRTYSNSEFMILDSVTLRNLEIVKNVRDEGDENSLYRILNHTKTPMGSRALKKWLLKPLLSVEKINYRLDAVEELTAKPLLRYDLRNWLSDVRDIERLVGRVVYGNSNARDLVALKKSLEALPPVRDSLLENIESTILNDIAVGLASFSELENLAEMIDRAIVDEPPISVREGGMIKSGYNAELDELKDIASNSRQWIANFQQKERERSGIKSLKVGYNKIFGYYIEVTNANSSQVPEDYIRKQTMANAERFFTPELKEKESLILTANEKAIALEYEIFTEILQTLSAHSRELQETAERIGTLDVLTDLAEVAENNNYIRPQLTDDCKILIRDGRHPVVENTVHGGFVPNDTEMDCKENQFLLVTGPNMAGKSTYMRQTALIAIMAQVGSFVPASYASIGIIDQVFTRIGAFDDLASGQSTFMVEMVELANILNNASPRSLVLLDEIGRGTSTYDGYSIAKAVVEFLHNRGKVGVRALFATHYHQLTALEEKLKRVKNYHVAVKEEGHELVFLRKIVPGATDRSYGIQVARLAGVPEKVIERANEILKELERENVLEEVEDSKNGKKRKSKATARYTQMMLFDPGDSGGNTAKVNRPSPVETVLKKLNVDEMTPIEALNKLHELKRLLN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: UL25_HHV6G
Sequence: MAQCNLFYQYPITPILEGHVRNILICTEKDVEKLQSQSSLRLREKIDQGHRDKLLRMRLKTELDALQKKMQKDSDVLNSHLKAIEDALLFTNDGEVNVETKADAQLIPKSPEKLEKFNQVAITPLDPFIRFTDDFRGEMINTFFNNAQMWNFTFGSWFYKLKRVFYNEPGLRRALKLTNVDSLTISKELLAVTVNALEQATVYPIFGSEMSDLEAALCILAAFYSTYENSQIDERTTLVDVITLLPVIFRLLGSEITALKNVSPSGTYFGFNDPSCMKFFVPMRKGKHYAENTFGNHVLIKMLLGRGVMQKIPGEKISQNFDVEARLHGAIKNDVLVYWTYQLMRPKLGNNVPIFIHDQHYLRSGLVAIESLFLLWRI
What is the function of this protein?
Plays a role at the late stage in the encapsidation of viral DNA, assuring correct genome cleavage and presumably stabilizing capsids that contain full-lengtht viral genomes.  Located on the external vertices of the T=16 icosahedric capsid, may bind together the tegument and the capsid through interaction with large tegument protein U31 (By similarity).
What are the official names of this protein?
Virion-packaging protein UL25 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL25 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL35_RUEPO
Sequence: MPKMKTKSSAKKRFKVTATGKVMAGQAGKRHGMIKRTTKFIRDARGTTTLSAPDAKIVKGYMPYDR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: COBQ_PSEA8
Sequence: MSDRGRTLMVQGTTSDAGKSTLVTALCRWLARRGVAVVPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLAPHTDMNPVLLKPNTDIGAQVIIHGRAVTSMDAAAYHDYKRVAMEAVLASHGRLAAAYRVVMVEGAGSPAEINLRANDIANMGFAEAVDCPVILVADIDRGGVFAHLVGTLELLSDSERERVRGFVINRFRGDIALLQPGLDWLEARTGKPVLGVLPYVSDLHLEAEDAIDTRQAAKVGPRLKVVVPVLPRISNHTDFDPLRLHPQVELSFVGPGQALPSADLIVLPGSKSVRADLAALRERGWDEAILRHLRYGGRLLGICGGLQMLGERLHDPLGLEGAAGSSAGLGLLALETTLEADKQLRNVQGRLSLEDAPLSGYEIHAGVTRGEALARPAVVLDDGRADGARSVDGNVMGTYLHGLFESTAACSALLRWAGLREVQAVDYQALRERDIERLADLVERHLDTGRLLALCGEPHA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: C2_CONVX
Sequence: MMSKLGVLVTICLLLFPLTALPLDGDQPADHPAKRTQDHNLASPISAWIDPSHYCCCGGGCTDDCVNC
What is the function of this protein?
In vivo, elicits a series of symptoms, such as being sedative, tail stiffening and twisted jumping, when injected intracranially into mice.
What are the official names of this protein?
Conotoxin Vx2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_LACAC
Sequence: MEITKDTIKHVATLSRLAFNEEELDKFTDQMGSIINMADQLSEVDTEGVEETVQVVDRDTVFREDIPEHWQGQTRETLMENVPEKANGYIKVPVIINKDEDE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: P4R3B_HUMAN
Sequence: MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).  May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 3B, SMEK homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SMEK family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.
Protein: Y4374_ARATH
Sequence: MEALRIYLWSLCLSLCLIIYGANSDPLEDKRALLEFLTIMQPTRSLNWNETSQVCNIWTGVTCNQDGSRIIAVRLPGVGLNGQIPPNTISRLSALRVLSLRSNLISGEFPKDFVELKDLAFLYLQDNNLSGPLPLDFSVWKNLTSVNLSNNGFNGTIPSSLSRLKRIQSLNLANNTLSGDIPDLSVLSSLQHIDLSNNYDLAGPIPDWLRRFPFSSYTGIDIIPPGGNYTLVTPPPPSEQTHQKPSKARFLGLSETVFLLIVIAVSIVVITALAFVLTVCYVRRKLRRGDGVISDNKLQKKGGMSPEKFVSRMEDVNNRLSFFEGCNYSFDLEDLLRASAEVLGKGTFGTTYKAVLEDATSVAVKRLKDVAAGKRDFEQQMEIIGGIKHENVVELKAYYYSKDEKLMVYDYFSRGSVASLLHGNRGENRIPLDWETRMKIAIGAAKGIARIHKENNGKLVHGNIKSSNIFLNSESNGCVSDLGLTAVMSPLAPPISRQAGYRAPEVTDTRKSSQLSDVYSFGVVLLELLTGKSPIHTTAGDEIIHLVRWVHSVVREEWTAEVFDIELLRYTNIEEEMVEMLQIAMSCVVKAADQRPKMSDLVRLIENVGNRRTSIEPEPELKPKSENGASETSTPSEI
What are the official names of this protein?
Probable inactive receptor kinase At4g23740.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.