PharMolix/UniProtQA huggingface dataset:
Protein: BIOB_SHEB5
Sequence: MSQLQVRHDWKREEIEALFALPMNDLLFKAHSIHREVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKEKDMPYLKQMVQEVKALGMETCMTLGMLSEDQANDLASAGLDYYNHNLDTSPEYYGDVITTRTYQNRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLPQHPDSVPINMLVKVAGTPFEKLDDLDPLEFVRTIAVARILMPLSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEESDDMGLFRRLGLRPEQGAAAKLEEESAVLAKAAAYQDKSSAQFYDAGAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: OADC_PSEFS
Sequence: MPKISHSALRRTFRELLATPTCVETASVFDPMSARIAADLGFEVGILGGSVASLQVLAAPDFALITLSEFVEQATRIGRVAQLPFIADADHGYGNALNVMRTVEELERAGVAALTIEDTLLPAQFGRKSTDLISIEEGIGKVRAALEARVDPELSIIARTNAGVLPTEAVIERTLAYQKAGADGICMVGVADFEHLEQIAENLTVPLMLVTYGNPKLNDAKRLASLGVRVVVAGHGAYFAAIKATYDSLRAQRQLTHSTDNLSATELTHTYTLPENYVAWAEEFMDVKE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
Protein: IPYR_RICTY
Sequence: MFIDKIKAKANNNEINVIIEIPMNSGPIKYEFDKESGAIFVDRFMQTTMSYPCNYGFIPDTLSNDGDPVDVLVVAHHPVVPGSVIKCRAIGVLMMEDESGLDEKIIAVPTSKLDITFDHIQELDDLCKMLKKRIVHFFEHYKDLEKDKWVKVTGWGNKVKAEDLIKEGIDRNQQKWNN
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T3HPD_AGRVS
Sequence: MRTNKVIHVIGVHAEGEVGDVIVGGVSPPPGDTLWEQSRFIASDETLRNFVLNEPRGGVFRHVNLLVPPKDPRAQMGFIIMEPADTPPMSGSNSICVSTAILDSGIISMQEPLTHMVLEAPGGVIEVTAECANGKAERINVLNVASFVTRLAAALEVEGLGTLTVDTAYGGDSFVIVDAIGLGFSLKPDEARELAELGMKITAAANEQLGFVHPCNADWNHISFCQMTTPITRENGILTGKSAVAIRPGKIDRSPTGTGCSARLAVMHARGEIGIGETYIGRSIIDSEFKCHIDSLTEIGGLSAIRPVISGRAWITGVSQLMLDPTDPWPSGYQLSDTWPAI
What is the function of this protein?
Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  Is likely involved in a degradation pathway that converts t3LHyp to L-proline.  Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity.
What are the official names of this protein?
Trans-3-hydroxy-L-proline dehydratase, T3LHyp dehydratase, t3HypD, Trans-L-3-hydroxyproline dehydratase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: ACDH_MYCBT
Sequence: MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLNEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the conversion of propanal to propanoyl-CoA, using NAD(+) and coenzyme A.
What are the official names of this protein?
Propanal dehydrogenase (CoA-propanoylating), Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: EFTS_SHISS
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAAF1_DROYA
Sequence: MSLSNRKEITGLTRMTPKGLKELCKKDKLYQTPRLNDTLYLHYQGFQCIEHLEEYTELKCLWLECNAISEIQGLEKLSKLKCLFLQNNLITKIENLEPCRELDTLNLSSNHIRKIQNIGTNILPVLNTLTIASNYLKDSESLSDLVQCKTLSVLDLSNNRIDDILIVKIFEQMLNLKVLVLQGNPVVSRLPQYRKTLILACKELTYLDSRPVFPRDRACAEAWKRDGYEGERKENNRWNRAERRKTRESINCTIRIRNSHRPPDQQDPLLRSSDSEDDTCTGTTLKKVALENGCVDDIWKEVSCEHPTSESGASTSSSVEDNDATSSQDDLIAEKLSNRGTLEGRPKVLNETEGSNLKRVNQNIKNVEPRNIQTIVFEEDVSKKSQVIIEEENVPKINLINEPCDLNDKKSIIVKCKKTGYTSIGPVHKKTVFHEDAEIKKMEDVVLCQDFIKSEEHMSSDFAVNSKLGKDIEQTCTAQRNEAQCKEFDEDQKIIEIESKLIHEMYESFEADDDDKLNETFDLNLYETTSEHHAHKVSFDENKMPMSCYQEDKESILLPKSMEETLFEEECFIANDKCAHDLEEIGRQMDEDLAELRQSTQNVVGLSKDEIAETDIETDEEDLLAQQDPYSPLLKQQFKNRRMKIMLIEESKAQGESQRDLNITVSNESGGDDKQDQLFARILDDATENIPKRIFGTGCDALSYNWPQEECLLQLTLSEVKETPAQESTFKNSITNSSSFEEANKICVHMDQKMAEEEEALGKLLHDLENEAEHVYEINTKMTYEETTSSKEVVSICTSLLDDIIVELTLNEILCHEKPKSFKFGPIESDEEFSYSLEPQLEKLVPPALEDPARGKSLRECLDTFSDFVSSMADPKLPLMLGRNPTLGVEKIRAAQELLKSKNLAEIYADSAESLNSQVAKEIEKRKRRVAATATRCFNQRDKYDDTLELVNNRLMIVKRDSGDLEELPPPPPLISDSESEDYDTADDEYTPGKGSHKLGSKPKDSKNLVTNSFLKEKQADSDVVEEVVKKNDHAEDEFYSLEAMTTFSSLDAEFFQKLDLQKVNDSEDSEPAINCMRNYNELQAYMKSGSLNHRMNTEETKTLQTSFSTVGSDEGKTKLRNPQEEKENALLKKMVLRMKEYEEREHQLQLVPHELGSVKLSLGGSKLFEQTPETVLVHTENEPTSKIKFIDNKKTNNDESTHLIKNYCEPLVRASCKTSNKSIDDDIQSDVSTDYESGEEVVVVEPPKLSEAVLKSFYSDGFEADLNMVHELEEATRRNLYCYHSNEMLNPTKNHPFSLKKTLSSKTSTNEVTVGAKAKWAKIAERLHEFLDPETISKLNKEQFGESDEFEDSQDANIFTDITFEENNSKKYENLVSEECNCTKSIYDENSCPSELNGNDQFSGLKEINKDKEMPTSNLELNSVMIQSKKKTSEILPNEIGNIIKACSSFEAPPTDPIGIEHFEDPTLTQMNPEFLKTKQIECNLQILSEDGDVVVQELSVNAQVSFE
What is the function of this protein?
Cilium-specific protein required for cilia structures.
What are the official names of this protein?
Dynein axonemal assembly factor 1 homolog, Defective transmitter-recycling protein, Leucine-rich repeat-containing protein 50 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: RNC_ACIBY
Sequence: MTKHQFKLSDPRLLSRIGYQFKQPELLQLALTHRSVSHKYNYERLEFLGDSLLGMIIANYLYHAYPHENEGRLTRMRATLVRQEALGKIATDLQLSRCLILSTGELKSGGHHRESILADTVEAIIGAIYLDSSDLNLLKDIVLKWYTPYLDHIEPTDQLKDPKSRLQEYLQARKKPLPVYEVVDIQGDAPHQHFKVECLVDGLSKIHGEGSSRRFAEQAAAAEILKLLEQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_SHEDO
Sequence: MGKTGSVEHTKQRIESELMPPSMYKVILNNDDYTPMDFVIEVLARFFDKHEPQATDIMLTIHHQGKGICGVYPFGIAETKVLQVNQFARENQHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RNH_MIMIV
Sequence: MLSLIVLLEKETLRFSQMVLAWGNGRVGASGGIGIHFPNGELQDISLEFDKGCCTNQRTELYAILYAIQYIDDNFDLNKCKVMIKTDSTYSVNSITKWAEGHSRNDWCKRTGEPIANREFIQEIYEYYQNFNIDFEWVEAHTGQTDSESIANAQADFLANSAAKRAARDKKICRPSSSGSKRNSREFYCEKSSKQVYNTPYRSKSRASINGFPIDDDFEIELVKRRSDN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Probable ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
Protein: RS3_GEOSE
Sequence: MGQKVNPIGLRIGIIRDWESRWYAEKDYADLVHEDLKIREYINKRLQDAAVSRVEIERAANRVNVTIHTAKPGMVIGKGGSEVEALRKALTQLTGKREHINIVEIKKPDLDAKLVAENIARQLENRVSFRRAQKQAIQRAMRPGRKGVKTMVVRRLGGAEIARSEHYSEGTVPLHTLRADIDYATAEADTTYGKIGVKVWIYRGEVLPTKKKAEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3, BS2, BS3/BS4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PURO_METKA
Sequence: MYVGRFLLAGKLEDGTPIAVYGVCSRSFSDRRIEVREGAAFVVPEDPSYITENPYVTYTCARIVDEFLVLTNGAQTDPIADKLESGVPPREALVSVTFAMDYEHDEYNTPRISLITDGETFWLGRVAPEEVYFRVMKPKDGEGYLLSVYGEYAEVPSKPNMTLDREDPLECDPVPSFEHYVCSVIARHDGGRWSLEAR
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: RL29_CAMJJ
Sequence: MKYTEIKDKTAAELATMLKEKKVLLFTLKQKLKTMQLTNPKEISQVKKDIARINTAINALR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYFB_SULIY
Sequence: MVTIVLNKYKLLDKIHIGQQKLEDLLFNLKSEVKPIDENNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYNVTDTEYTLIVDNVRTRPYALAAIVYNAKIDLEELIQFQEKLHGTIGRKRKKVAIGIHDLRKVDSKTIEYKEVPLSYKFVPLYGNKELTISEILEKTEQGKLYGNISIANGVSPAIVQDDGEVLSIPPIINSNKTRLDENTKDFFIDVTGTSFEAVAQTLDIIVSNLAEAGGTIGRVKVLKSANSSQLSSPLFLHKIQNVREEYVKKILGIKTSKEEICKHVMRMRMNCDIENGVIRVTVPQYRVDILNEIDVVEDIAMSIGYNNLEPSKYISTNYGSYDYMTLLERKIRELGIGAGYVEISNFVLIKDEKLFSNKYVKILNPVTEEYNAVRDSLIPGLLDFLSKNQHAKFPIRVFETGDVVVYDSSTDTGFRNDKRAAYAIMDNKVSYEDIQAPIHYILKSLGLEVNYKEENNNIFIEGRSASIFYENEKMGVIGEVNPDVLIRFGIEYPAVIAELYISEIGKRLTNQR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CUPTR
Sequence: MPRVKRGVTARARHKKVIDAAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWIARINAATREHGMTYSVFMNGLKKASIELDRKVLSDMAIHDKPAFAAIVNQVKATVA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RIMP_DESVV
Sequence: MTKQALDATIADMAGPFLASLGLELWGIELSYGGRTVVRLFVDGPEGVTIDQCAEVSRHVGLALEVEDVISSAYVLEVSSPGLERPFFRAEQMSPYVGRQIELTLIDPTPEWPGRRKFRGELLAVEGDTVVLRPEGAPAPEAEEAVLRTSWQGVRKANLIHVFPEPGHKPRR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3158_BORA1
Sequence: MLRVVLITGISGSGKSVALRMLEDSGFTCVDNLPLRFLTEFVAVSHDDGMERVAVAIDVRSPGELAELPNVITALRAMGTQLSVVFLDASTETLAQRYSESRRRHPLTDRASRGEKSASLTDCIALERELLAPLRDQEHVIDTTDLTPGQLRSWIRELIDADRAPLVLTFQSFAYKRGVPNDADLVFDVRCLPNPYYDRNLRPLTGRDQPVADWLAGFEIVQRMIDDIDGFIRRWLPQYTLDTRNYLTVAVGCTGGQHRSVYVVEELARRFSEHDPLLVRHRTQLPDESA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BAV3158.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LOLA_SALDC
Sequence: MKKMAIACALLSSVVASSVWADAASSLKSRLDKVSSFHATFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQASDWQQYNIKQDGDNFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSAYQLKSQQNGAVDPSKFTFTPPQGVTIDDQRK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GPR15_CHLAE
Sequence: MDPEETSVYLDYYYATSPNPDIRETHSHVPYTSVFLPVFYIAVFLTGVLGNLVLMGALHFKPGSRRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLWRTGSFLCKGSSYMISVNMHCSVFLLTCMSVDRYLAIVCPVVSRKFRRTDCAYVVCASIWFISCLLGLPTLLSRELTLIDDKPYCAEKKATPLKLIWSLVALIFTFFVPLLSIVTCYCRIARKLCAHYQQSGKHNKKLKKSIKIIFIVVAAFLVSWLPFNTSKLLAIVSGLQQERYFPSAILQLGMEVSGPLAFANSCVNPFIYYIFDSYIRRAIVHCLCPCLKNYDFGSSTETSDSHLTKALSTFIHAEDFTRRRKRSVSL
What is the function of this protein?
Probable chemokine receptor.  SIV-1 coreceptor.
What are the official names of this protein?
G-protein coupled receptor 15, Brother of Bonzo, BoB.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AFP2S_MALPA
Sequence: SDYSRKRDPPQKYEEE
What is the function of this protein?
Possesses antifungal activity against P. infestans but not F. graminearum.
What are the official names of this protein?
Antifungal protein 2 small subunit, CW-2.
Protein: PYRF_MUCCL
Sequence: MNTYKTYSERGQQHPNACARSLFELMERNESNLSVAVDVTTKKELLSIADAVGPFVCVLKTHIDIVEDFDHDLVAQLEQLAKKHDFLIFEDRKFADIGNTVKHQYANGIYKIASWSHITNAHTVPGEGIIKGLGEVGLPLGRGLLLLAEMSSKGALTKGSYTSESVEMARRNKDFVFGFIAQHKMNEHDDEDFVVMSPGVGLDVKGDGLGQQYRTPHEVIVESGGDIIIVGRGIYGNPDQVEAQAKRYRQAGWDAYLERVRLHKK
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: DDLA_CHRVO
Sequence: MGKIRVGLIFGGQSSEHEVSLQSARNILQAIDGERFEVSLIGVDKQGRWHASQASNFLLNADDPGRIALRESGENLALVPGECSGQLQTAANAHPLAQIDVAFPIVHGTLGEDGSLQGLLRMANIPFVGAGVLGSAVCMDKDVAKRLLRDAGLKVAPFVSLTRSKAAGADLSAIVEQLGLPLFVKPANQGSSVGVSKVKREADLRAALDEAFRYDHKVLVEQAVIGREIECAVLGNERPRASGCGEIVLSDEFYAYDTKYLNEDGARVAVPADIPDEACQRIRGIAIEAFQALECSGMARVDVFLTPDGEVVINELNTLPGFTNISMYPKLWQAAGMSYRELITALIELALEKGRMDEALSRSCQY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_RHOBA
Sequence: MIARMSTRRRAREIVLQLLYEADLNDWRDAATSRKFIRSRLQGRKVLTDFAAELLDGTMARRDDIDAKLTKLSTNWALHRMPVTDRNVLRLGAYEILYSGTPGQVAISEALTLAKRYGGENSPRFINGVLDRLFKYHSNPESVSS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SATT_HUMAN
Sequence: MEKSNETNGYLDSAQAGPAAGPGAPGTAAGRARRCAGFLRRQALVLLTVSGVLAGAGLGAALRGLSLSRTQVTYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLEDSGPPPVPKETVDSFLDLARNLFPSNLVVAAFRTYATDYKVVTQNSSSGNVTHEKIPIGTEIEGMNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQKATKKGEQELAEVKVEAIPNCKSEEETSPLVTHQNPAGPVASAPELESKESVL
What is the function of this protein?
Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.
What are the official names of this protein?
Neutral amino acid transporter A, Alanine/serine/cysteine/threonine transporter 1, ASCT-1, Solute carrier family 1 member 4.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: YEH2_YEAST
Sequence: MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKNDPRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDSTGYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENLRFPNAR
What is the function of this protein?
Mediates the hydrolysis of steryl esters.  Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism.
What are the official names of this protein?
Sterol esterase 2, Steryl ester hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: PHLC_PAESO
Sequence: MKRKFTKTVLNAVFVLGLCSIMGGTSYAWDGKKDGTGTHALIAEHGLTMLNNDLNQNEPKPIKQNIEILNKYLKDLKLGSTFPDYDPNAYDLFQDHFFDPDTGNNFTLDNKWYVASPIYDTAETQVRKFATLAENEWKKGNYKEATFLLGQGMHYLGDLNTPYHAANVTAVDSPGHVKYETFVENRKENYALNTAGNDTTQGIYKDAVANKDFDQWMTQNSVKYAKKAKALYYSHSTMKHNWDDWDYSGREAIKNSQVCTAGFLYRFINEVSEDQISGNNLTNEFNVVLKTADNEYAGTDDNVYFGFETKDGSKYEWNLDNAGNDFEKNQTDNYILKVKNDVKVNTNDITKYWVRKENRTPISDDWELSNIKLISNGKVILQKDINKVFSGNQVYDINK
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture.  Binds to eukaryotic membranes where it hydrolyzes phosphatidylcholine, sphingomyelin and phosphatidylethanolamine.  The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage (By similarity).
What are the official names of this protein?
Phospholipase C, PLC, Phosphatidylcholine cholinephosphohydrolase.
What are the subcellular locations of this protein?
Secreted.
Protein: LYSX_MYCUA
Sequence: MTVTKPRSVQSRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQFWTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVCLASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSSGIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRTLITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLEPVGISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHNB_PSEAE
Sequence: MRITLLDNFDSFTYNLVEQFCLLGAEVRVMRNDTPLPTIQAALLADGCELLVLSPGPGRPEDAGCMLELLAWARGRLPVLGVCLGHQALALAAGGAVGEARKPLHGKSTSLRFDQRHPLFDGIADLRVARYHSLVVSRLPEGFDCLADADGEIMAMADPRNRQLGLQFHPESILTTHGQRLLENALLWCGALAVRERLRA
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, a precursor for Pseudomonas quinolone signal (2-heptyl-3-hydroxy-4-quinolone; PQS) production which is required to induce the genes for the biosynthesis of the virulence factor pyocyanine (PCN), a characteristic blue-green phenazine pigment produced by P. aeruginosa (PubMed:11591691, PubMed:2153661, PubMed:23449919).  In the first step, the glutamine-binding beta subunit (PhnB) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (PhnA) to produce anthranilate (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, pyocyanine specific, AS, ASII, Anthranilate synthase beta subunit, pyocyanine specific, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: ARC4_PHAVU
Sequence: MGSSKLLSLALLLVLLTHANSASETSFNFTSFDTNKLILQGDASVSSKGQLLLTKVRGNGDPTVDSMGRAFYYAPIQIRDSTTGKLASFDTNFTFSIRPYSNNENSAFGLAFALVPVDSEPKRKDYFLGLFNKPDDPEAHIVAVVFDTSSNQIEIDMNSISPVARESCHFHKYNGEKVEVRITYDSSKKNLRASLVYLREQSATSSTSSVHMEKVLNDWVSVGFSATSGLYDPTSETHDVLSWSFSSKFSQHTTSERSNFLLNMFL
What is the function of this protein?
Seed storage.  This carbohydrate-binding lectin has toxic effects on the important bean bruchid pests, Z. subfasciatus and A. obtectus.
What are the official names of this protein?
Arcelin-4.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.