PharMolix/UniProtQA huggingface dataset:
Protein: TTUB_THET2
Sequence: MRVVLRLPERKEVEVKGNRPLREVLEELGLNPETVVAVRGEELLTLEDEVREEDTLEVLSAISGG
What is the function of this protein?
Required for the 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2-thiouridine (m(5)s(2)U or s(2)T) (PubMed:16547008, PubMed:28439027).  This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is essential for cell growth at high temperatures (PubMed:16547008).  Thiocarboxylated TtuB functions as the sulfur donor in the sulfurtransferase reaction catalyzed by TtuA (PubMed:28439027, PubMed:19037260).  TtuB also functions as a protein modifier covalently attached to lysine residues of the target proteins TtuA and TtuC (PubMed:22467871).  TtuB conjugation might play a regulatory role to ensure appropriate sulfur transfer in cells (PubMed:22467871).
What are the official names of this protein?
Sulfur carrier protein TtuB, 2-thiouridine synthesis sulfur carrier protein TtuB, Ubiquitin-like S-donor protein TtuB, Ubiquitin-like protein modifier TtuB, tRNA two-thiouridine-synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the TtuB family.
Protein: HIS7_NITHX
Sequence: MRTATIKRKTKETDIEVAVNLDGSGVSSVATGIGFFDHMLDLLARHSRIDIMVKADGDLHVDYHHTTEDVGIALGQAVKQALGTMAGITRYACAHMPMDETLSRVVIDISGRPMLVFKVEFPRDKIGEFDTELVREWFNAFAVNAGVTLHVETLYGENSHHIAESCFKGLARALRAAVAIDPRAAGEVPSTKGQLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y703_ENCCU
Sequence: MHLRPSPQSPQSACCNPELPATEPPTPAEHPTAFRRSQAPSRTPRTFSRETLHILRENRCLAVSKVVHTPDIPPKTPASQAASNRAHRTAKHPARRQSCKLKAPNPCVGHPLRIPSPKHSPRHCTLHDIRHRKKLHPLNNPKGANKRKTPPLIQPTVLEPLPHPVLSPHNISSSTDHPDPSPAIKPSPPNNTRHILLTTKSLLLILTHPIISAYPFHPYFSFTPHEHHIRSRDTQN
What are the official names of this protein?
Uncharacterized protein ECU07_0030/ECU09_2040.
Protein: GUAA_WIGBR
Sequence: MNNQYILIIDFGSQYTKLVARRMKDIGAKFIISSWEIKKKELLKKNIKGILLSGSPMSVLDDKSPYVSKDILNMKVPILGICYGMHTLVKQLGGKVERKSVREFGYASIKILKNHSNLFYDNFEVSEKNYTKRQKVWMSHEDSVINIPKGFSIIASTKNCKYAAIFNKKNKFYGVQFHPEVTHSEKGYLILNRFVKNICNYTNVIKYSLSIRKIILKIKNKVNDEKVILGLSGGIDSFTSAILIHKAIGNNLFCICIDNGLLRNDEILKIKNLIKKVGKINVIYINHKKRFLKSLNGITDPEKKRKTIGNLFFKIFQEQADILKAKWLAQGTIYPDIIESSQNNLLKKDNFIKSHHNVCPLPKGIKLKILEPLKHLFKDEVKKIAKKIGIPKEIIFRHPFPGPGLAVRIIGEIKEEYCNILRMADEIFISELKSENLYFNISQAFSVLLPIKSVAVMGDMRKYEWVISLRAIETLDFMSANWANIPYKILNNVSNRIINEVRGISRVVYDISNKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TSAD_BACC1
Sequence: MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL1_OSTLU
Sequence: MDDAPGASDEAREPLLKRVGASVEGTSLMNHRLMKNPKFRALLVESLMALTTFSFMAKQTEGLAGPELSTLNDCGEAGCGFTKFYQFKGVVGVYAGFWAYTVILIAMYVIRKAPPPGTEFASYALFTAAMATFVVMSITECASVVLSSDYYVCKNADYSLVSLIFAAATIVLNCLTCAFAWRQWGELKFVGLPKTLSALTETYPG
What are the official names of this protein?
CASP-like protein 0U1, OlCASPL0U1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3C_DROER
Sequence: MSRFFANGSDSESESSEDEIQATNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDSGVKPTEAAPKAVKTAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKEEKDDDKRKDKRKEQKIKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAEEHEEYVTAPFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYKFDPEVLKKKRGEVPATTSTSVDVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQENVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQQVQTIDEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XDHC_ECO57
Sequence: MNHSETITIECTINGMPFQLHAVPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
What is the function of this protein?
Iron-sulfur subunit of the xanthine dehydrogenase complex.
What are the official names of this protein?
Xanthine dehydrogenase iron-sulfur-binding subunit.
Protein: KADA_PYRFU
Sequence: MPFVVIITGIPGVGKSTITRLALQRTKAKFRLINFGDLMFEEAVKAGLVKHRDEMRKLPLKIQRELQMKAAKKITEMAKEHPILVDTHATIKTPHGYMLGLPYEVVKTLNPNFIVIIEATPSEILGRRLRDLKRDRDVETEEQIQRHQDLNRAAAIAYAMHSNALIKIIENHEDKGLEEAVNELVKILDLAVNEYA
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_CERS5
Sequence: METARGRVLSVASECVPLLKTGGLADVVGALPGALAAEGWEMRVLMPCYRPLRWRLEQMEEVFSEEDLFGGRGRVMAGEVAGRRMLLLDAPHLYDREGGPYAGPWGDWGDNAQRFAALSWIAARIAREGLSDGWRPEVLHAHDWQAGFAPAYLAYWGSGGVRSVLTVHNIAFQGWAPAALLPSLRLPASEFHPAALEYYGGLSSLKAGLVTADHITTVSPTYACELMRPEFGMGLQGVIAARAGQVSGILNGVDTDIWSPEAEERPYTARSLKAKAENRAVLSGAFKLDVPGPLAILVSRLTYQKGIDLIPEVLPDFIAAGGGLAVLGTGDAALEGAMRELEVRFSGRVGVRIGYDEGLSHLMFAGGDAVLVPSRFEPCGLTQMYGLRYGAIPVVALTGGLADTIINANPAALTAGCATGLTFHPTEPPAFAEALRRLIHLYADHALWEKVQKNAMRHPVGWQTSAAAYAALYRELVA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: THIO2_PLAF7
Sequence: MKKYIFFFLFSFINFFFVYDVTCTKEVTSTNDDPLTPLNRFDKYYLRMFKKVPRLQQNGSNIINGVNMKNTVIVLYFFAKWCQACTMQSTEMDKLQKYYGKRIYLLKVDLDKNESLARKFSVKSLPTIILLKNKTMLARKDHFVSSNDLIALIKKHL
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (PubMed:16910770, PubMed:22355694).  As part of the translocon PTEX complex, plays a role in the export of parasite proteins into the host erythrocyte (By similarity).  The translocon PTEX complex is a multi-protein machinery resident in the parasite parasitophorous vacuolar membrane, responsible for protein secretion into host cells (PubMed:19536257).  May contribute to the unfolding of proteins containing the PEXEL localization motif before their passage through the translocon or regulate the PTEX complex function (PubMed:19536257).
What are the official names of this protein?
Thioredoxin 2, PfTRX2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Parasitophorous vacuole membrane; Peripheral membrane protein. Note=Appears to localize to other uncharacterized organelles.
Protein: FTSQ_MYCBO
Sequence: MTEHNEDPQIERVADDAADEEAVTEPLATESKDEPAEHPEFEGPRRRARRERAERRAAQARATAIEQARRAAKRRARGQIVSEQNPAKPAARGVVRGLKALLATVVLAVVGIGLGLALYFTPAMSAREIVIIGIGAVSREEVLDAARVRPATPLLQIDTQQVADRVATIRRVASARVQRQYPSALRITIVERVPVVVKDFSDGPHLFDRDGVDFATDPPPPALPYFDVDNPGPSDPTTKAALQVLTALHPEVASQVGRIAAPSVASITLTLADGRVVIWGTTDRCEEKAEKLAALLTQPGRTYDVSSPDLPTVK
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: FABZ_THENN
Sequence: MNIDYVRSILPHRYPFLLVDGVIEESEDRIVAFKNISISDPVFQGHFPEYPIYPGVLIIEGLAQTAGILLLKDLEGIPLFLGIDEARFKKEVRPGDKLIYEVKKIGEKLGTVQVEGVAKVENTIVAKAKLLLGVKKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_FERNB
Sequence: MNIVCYGLQWGDEGKGKVTTYLSREFDYVVRYSGGSNAGHTVNYGEFKLVHHLVPSFDIRGNTKAYIANGVVVDLDVLIKEIEEIKKIGFDVYDRINISSLTHIVLPVHKMLDEKLEIAKGEKAVGTTKRGIGPAYADKVHRIGLRLVDLFDKETALEKLKFISKMYKNLYGIEWDDYEILFENFEKLSRIIVPPLEMKEELKNANVLFEGTQGVLLDIDMGSYPYVTGSYCNTTGVESGLGFPIKIDKRIGVFKAYVTRVGKGPFPTELFGEEAEKIRIAGREFGATTGRPRRCGWLDLPILRYAIETSGCDEMIMTKADILSGLEKVKVGIRYLSNGRKFEIPNDISMIDKVTVEYIEFNGWKNLEDDNFAKFVDFIERETGLKIAYISTGEKIDDIRKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CHLPD
Sequence: MRIVFMGTPEFAVPSLRSIAAEHNHFELVLVVTGSDKPRRGRNAPSEPSPVKSAALELGFQVYETDDVSSSDFLSVVADSAPDVIVVAAFRILPPEVYGQAKLGAFNLHASLLPAYRGAAPINWAIINGEKESGVTTFFLQKTVDTGNVIMQEKIPVLPDDNASILSVKLSHLGAELVVKTLRSIQAGTVEVQAQDDAFFSRAPKLTRENTRIRWNQPVAVLSDFIRGLAMKPAAWTTVQNRTMKIFRAIPFTEEITSSIEQPGSILVERGRFLVRGSDGWLEVKQLQPEGRKPMEGAEFARGFRPESGTSLLFE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RECO_BACTN
Sequence: MLQKTKGIVLHTLKYNDTSIIVDMYTELSGRTSFLVPVPRSRKAAVKSVLFQPLSFIEFEADFRPNATLYRVKEAKSFYPFTSIPYDPYKSSMALFLAEFLYRAVREEAENRPLFAYLQHSVIWLDECREGFANFHLVFLMRLSRFLGLYPNLEDYHTGDYFDLLNACFTSTRPQLHSSYINPEEAGRLRQLMRMNYETMHLFGMSRAERTRCLTIMNDYYRLHLPDFPALKSLDVLKELFD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: FRDA_MACFA
Sequence: MWTFGRRAVAGLLASPSPAQAQTLARAPRLAELAQLCSRRGLRTGINATCTTHHTSSNLRGLNQIRNVKRQSVYLMNLRKSGTLGHPGSLDDTTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLGAELTKALKTKLDLSSLAYSGKDA
What is the function of this protein?
Modulates the RNA-binding activity of ACO1.  May be involved in the cytoplasmic iron-sulfur protein biogenesis.  May contribute to oxidative stress resistance and overall cell survival.
What are the official names of this protein?
Frataxin, mitochondrial, Fxn.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion.
Protein: PROBD_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQAVVCGIYEEPVTPGQCNMVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NTL9_ARATH
Sequence: MGAVSMESLPLGFRFRPTDEELVNHYLRLKINGRHSDVRVIPDIDVCKWEPWDLPALSVIKTDDPEWFFFCPRDRKYPNGHRSNRATDSGYWKATGKDRSIKSKKTLIGMKKTLVFYRGRAPKGERTNWIMHEYRPTLKDLDGTSPGQSPYVLCRLFHKPDDRVNGVKSDEAAFTASNKYSPDDTSSDLVQETPSSDAAVEKPSDYSGGCGYAHSNSTADGTMIEAPEENLWLSCDLEDQKAPLPCMDSIYAGDFSYDEIGFQFQDGTSEPDVSLTELLEEVFNNPDDFSCEESISRENPAVSPNGIFSSAKMLQSAAPEDAFFNDFMAFTDTDAEMAQLQYGSEGGASGWPSDTNSYYSDLVQQEQMINHNTENNLTEGRGIKIRARQPQNRQSTGLINQGIAPRRIRLQLQSNSEVKEREEVNEGHTVIPEAKEAAAKYSEKSGSLVKPQIKLRARGTIGQVKGERFADDEVQVQSRKRRGGKRWKVVATVMVAVMVGVGMGIWRTLVSS
What is the function of this protein?
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:18443413, PubMed:24329768).  Calmodulin-regulated transcriptional repressor.  Binds several synthetic promoters with randomly selected binding sites (PubMed:17947243).  Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P. syringae.  Binds directly to the promoter of the PR1 gene (PubMed:22826500).  Acts as positive regulator of innate immunity.  Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression (PubMed:24329768).  Mediates osmotic stress signaling in leaf senescence by up-regulating senescence-associated genes (PubMed:18443413).
What are the official names of this protein?
Protein NTM1-like 9, Calmodulin-binding NAC protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon osmotic stress or pathogen attack, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Protein: HV01_CANLF
Sequence: EVQLVESGGDLVKPGGSLRLSCVASGITFSGYDMQWVRQAPGKGLQKVAYFNDALSAQGYADAVKGRFTISKDNAKDSLYLQMNSLRAEDTAVYYCAPWQFEYWGQGTLVTVSS
What are the official names of this protein?
Ig heavy chain V region GOM.
Protein: BCHL_CERSK
Sequence: MSPKDLTIPTGADGEGSVQVHLDEADKITGAKVFAVYGKGGIGKSTTSSNLSAAFSILGKRVLQIGCDPKHDSTFTLTGSLVPTVIDVLKDVDFHPEELRPEDFVFEGFNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKQHHLLDDTDVVIFDVLGDVVCGGFAAPLQHADQAVVVTANDFDSIYAMNRIIAAVQAKSKNYKVRLAGCVANRSRATDEVDRFCKETNFRRLAHMPDLDAIRRSRLKKKTLFEMDEDQDVLAARAEYIRLAESLWRGLDPIDPHSLPDRDIFELLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RL22_THEMA
Sequence: MKLQVPRNGLKRSLFHKKRKELLSSLPKIEARAVAKYIRISPRKARAIANTIRGKSVEEAFQILAFSPKKAARIMEKVLKSAVANAENNFGLSVENLYVSECYVNDGPRMKRIWPRGRGRADIIQKRMSHITVVVRDRSREDEYRKALEELQKKISSEE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SINL9_ARATH
Sequence: MVLASISEALISQGDGGERVAKRQRSAIVLLDLDILDCPICCEALTSPIFQCDNGHLACGSCCPKLSNKCPACTLPVGHSRSRAMESVLESILIPCPNVRFGCTKSFFYGKESAHEKECIFSQCSCPSSVCDYTGSYKDLYAHYKLTHSTNIFWNIKRFRCANFFTTSMLISDKILIKRVHEKKLLLAVQCFREPCGVYVTVSFIAPSAPEVGEFSYQLSYNVDGHTVTYESPEVKRVCKVSIETPQENFMLIPHSLLRGDLLEMQVFIIENVDQE
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase SINA-like 9, RING-type E3 ubiquitin transferase SINA-like 9, Seven in absentia-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: CRCB1_MYCTU
Sequence: MPNHDYRELAAVFAGGALGALARAALSALAIPDPARWPWPTFTVNVVGAFLVGYFTTRLLERLPLSSYRRPLLGTGLCGGLTTFSTMQVETISMIEHGHWGLAAAYSVVSITLGLLAVHLATVLVRRVRIRR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SQD1_SPIOL
Sequence: MAHLLSTSCSMKVSPSEKLSSKCWNIGSTKYPMSFTQQTSKSAFKSLVHQRNNTQKLTVVRATTVPLNQETKAESGTSSFENNGNTSGRKRVMVIGGDGYCGWATALHLSKKNYDVCIVDNLVRRLFDHQLGLDSLTPIASIQNRIRRWQGLTGKTIDLHVGDICDFEFLAETFKSFEPDTVVHFGEQRSAPYSMIDRSRAVYTQQNNVIGTINVLFAIKEFSEECHLVKLGTMGEYGTPNIDIEEGFITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWGIRATDLNQGVVYGVMTEETAMHEELCNRFDYDAVFGTALNRFCVQAAVGHPLTVYGKGGQTRGYLDIRDTVQCVELAIANPAKLGEFRVFNQFTEQYSVRDLAALVTKAGEKLGLNVETISVPNPRVEAEEHYYNAKHTKLAELGLKPHLLSDSLLDSVLNFAVQYKDRVDTKQIMPSVSWKKIGVKPQTLRA
What is the function of this protein?
Involved in the biosynthesis of sulfolipids found in thylakoid membranes.  Converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose.  The sulfite is delivered to the reaction center by the FMN-binding domain of FdGOGAT.
What are the official names of this protein?
UDP-sulfoquinovose synthase, chloroplastic, SoSQD1, Sulfite:UDP-glucose sulfotransferase, Sulfolipid biosynthesis protein.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SDHD_PSEP1
Sequence: MIHGKTLEAWQQSHPIIAELVALKPTSWFNPGIAKAAEALHDVGLTAADVQAASARLLRFAPYLATVFPETAAAGGVIESPVIPLPQLRRVLVEEGSLQNAGSLWLKADSDLPISGSIKARGGIHEVLKHAEDLALAAGLITPTDDYTKLASDQARAFFSQYTIAVGSTGNLGLSIGIMSAKLGFQVSVHMSSDARQWKKDKLRANGVTVVEHASDYSVAVEQGRQQAASDPRCYFVDDENSPQLFLGYAVAAERLARQFDQAGIQVNADHPLFVYLPCGVGGGPGGVAFGLKLVFGDAVHCIFAEPTHSPCMLLGVYTGLHDETSVQDFGIDNITAADGLAVGRPSGFVGKAMQRLIDGYYTVADEELYRLMVIAHEQDKVKLEPSALAGVPGMLRVLQAGEYLARQGFTPTQLQQATHLVWGTGGSMVPDDEFNTYLAKGRSLQANV
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: PFDA_HALLT
Sequence: MMGGGQQQLQQLSQELQALDEEIEALEVEIDDHREEQSDIDDAIEAIETLDSGSTVQVPLGGGAYVRAEVQDIDEIIVSLGGNYSAEQSEEDAIDVLGRKRDALDDRIEETQEEVDELESESQELEQQAQQMQQQMQQQQMQQMQQSQGDEE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBG_PLAFO
Sequence: MPREIITLQCGQCGNQIGVEFWKQLCNEHNIDQEGILKNNNFLNEDRKDIFFYQADDEHFIPGALLFDLEPRVINSIQTSEYRNLYNPENMFISKEGGGAGNNWGCGYSQGHKVEEEIIDMIDREVDNSDNLEGFILSHSIAGGTGSGMGSYLLELLNDNYSKKMIQTFSVFPLLTNESSDVVVQPYNSILTLKRLILSTDSVVVIDNTSLNRIFVERLKLNNPTFQQTNTIISNVMSASTTTLRYPGSMNNDMISLISSLIINPKCHFLITSYTPITIDKHISNVQKTTVLDVMKRLLHTKNIMVSAPVRRGMYISILNIIRGETDPTQVHKGLQRIRDRKLVNFIKWNPASIQVTLAKQSPHVVSQHKVCGLMMANHTSISTLFERCVTQFDRLYKRRAFLENYKKESMFSSADGQGNFEEMESSKEITQNLIDEYKSAERDDYFTNTYI
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma chain, Gamma-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SWF1_DEBHA
Sequence: MSLPFTVIICIVLLSAILISIVIFGNSPNFRNTPIYKLRLKILRWNHDIIAWINYVDSHVFGNKLVFYSGWLVPLFYIIVVSFCLHQFFTKVYKLLPLFVRKSGFHSTYIAFTILCIFIDTFMATFSNPGKITTGNVDKVDNFFQNNELIFFADNYCSTCEIIKPARSKHCSICNNCIMLFDHHCIWVNNCVGYYNYKWFMGFLIANINLLGYGGYLCYQAMSSTKTEFPTLSYWKTIISTNDSNKATGVLLILCVIFIMIAVLFTGLHLRYLYLGVTTNECDKWSEVEYLISLGSLYQVIDSNLNEKYVEKCVIMNHDNDSYETVFISLKNENVLFSSNDGINLRKIESMEDDLINIYDHGFVDNLKERMFNRVLN
What is the function of this protein?
Palmitoyltransferase that targets several endosomal SNAREs.  Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain.  May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
What are the official names of this protein?
Palmitoyltransferase SWF1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.