PharMolix/UniProtQA huggingface dataset:
Protein: VGLU2_HUMAN
Sequence: MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQDTGETIELTEDGKPLEVPERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPSGWEKKEEFVQGEVQDSHSYKDRVDYS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate (PubMed:33440152, PubMed:11698620).  At the synaptic vesicle membrane, mainly functions as a uniporter which transports preferentially L-glutamate but also, phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:11698620).  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:11698620).  In addition, functions as a chloride channel that allows the chloride permeation through the synaptic vesicle membrane therefore affects the proton electrochemical gradient and promotes synaptic vesicles acidification (By similarity).  Moreover, functions as a vesicular K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake (By similarity).  The vesicular H(+)/H(+) antiport activity is electroneutral (By similarity).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (Probable) (PubMed:10820226).  The symporter activity is driven by an inside negative membrane potential and is electrogenic (Probable).  Also involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity).  May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome. Cell membrane; Multi-pass membrane protein.
Protein: HIS5_THEKO
Sequence: MIAVVDLGIGNLANVRKALGGVITSDPYAIEGAEKIVLPGVGNFGAVMEKLEPLRGVIIDAINDGKPLLGICLGLQLLFEGSEESPGKPGLGVFRGNVVRFQGVRVPHIGWNQVWQRKECPLFEGIKDGAYFYFVHSYYALPEEDVTVGVTDYESKGAKVVFTSAVCRDNVYAVQFHPEKSGRNGLRLLENFRRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_CHLPM
Sequence: MTREKVPAKGKARTSGGPGEPVYCSFCGRSSQEVDSMVAGPNAFICDRCIRTSHDILRKELSAIQHPEPVADQPFPVKLVSPKALMESLDQYVVGQERAKKALSVAVYNHYKRIDSQEWQHDDDEVVIEKSNIMLIGPTGTGKTLLAQTLANLLEVPFSIVDATSLTEAGYVGDDVETILARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGAVVGVPPKGGRKHPEQQLININTKNILFICGGAFEGLDRLIARRMSKSSMGFGAGVADKKAGYDPGILKFVMQDDLHEYGLIPEFIGRLPVLSSLEPLDEHALRSILVEPKNALIKQYAKLFEMDGVELEFAPESLDRVVAIALERGTGARALRSVLENVMIDIMFELPSMKGIGKCIITADTIDGTGSPTYLTEDGKKKKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: C3390_DROME
Sequence: MAEPLAVETKPLSNGNANGNAVGIAESASAVFQEKLKLQQQEESNEIAAVPKYGLKLKFDHVWPEKRIQNVRASIRQTLPMVPLVCRYAAYYWKVSREGRRVYMDYYYMENGKQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPKGCTIFQSLLSKCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGLYPRSWTEYDLSHYGVRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGTGNKKQDAEGGAESQLISEGNAKGVSIRQKISEMPCSYNLACRVLPEISITRCPQFDPAGNGEQLWAQLKEHGQLSEHPTSEALKTKDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQFPRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWLKCDSSLGKELAYDDPRLAYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYYVLNELAQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETNGKVYLMDAIGYLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDLSHSHRDTIMADQLCGHWYLKSCGFDYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVYALAATMIQEGMFEEAFQTAGGMYKTLSQRIGMNFETPEALYGEKRYRSIGYMRPLSIWSMQVALERRRAQRD
What is the function of this protein?
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide.
What are the official names of this protein?
Non-lysosomal glucosylceramidase, NLGase.
What is the protein family that this protein belongs to?
Belongs to the non-lysosomal glucosylceramidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: G6PI2_RHOJR
Sequence: MTHIVTDTPLWKKLSDHHWEVVGTHLRELFDTDPDRGVDLIVTAADLYIDYSKHRVTRETMGLLVDLARAAGVERHREAMFTGAHINTSEDRAVLHTALRANPERELIVDGQDVVGDVHTVLRRMGEFTDRVRSGAWRGATGERIRTVVNIGIGGSDLGPAMAYRALRHYVDGPEVRFVSNIDPADLLSNLTDLDPRTTLFVVVSKTFSTLETMTNASAARRWITEALGEHAVPRHFVAVSTDEERVTAFGITARNIFGFWEWVGGRYSVGSAAGLSVMIAIGRERFTEFLGGMRAIDEHFRTTPLESNAPVILGMLGVWYSSFFGADARAVLPYAHDLARFPAYLQQLTMESNGKSVRTDGTPVGTFTGEIFWGEPGTNGQHAFHQLLHQGTHLIPVDFLGFAEPIEDLPTLDGIGSVHDVLTANLFAQSKVLAFGKNADEVAADGTPSALVPHKVMSGNRPSTTILGAKLTPSTLGQLIALYEHQVFVQGIVWGIDSFDQWGVELGKTSALELGPALWDLDGAAYVGDSSTTGLIRTYRLARGERRCLP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 2, GPI 2, Phosphoglucose isomerase 2, PGI 2, Phosphohexose isomerase 2, PHI 2.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_ECOSE
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: UCRIA_ARATH
Sequence: MASSSLSPATQLGSSRSALMAMSSGLFVKPTKMNHQMVRKEKIGLRISCQASSIPADRVPDMEKRKTLNLLLLGALSLPTGYMLVPYATFFVPPGTGGGGGGTPAKDALGNDVVAAEWLKTHGPGDRTLTQGLKGDPTYLVVENDKTLATYGINAVCTHLGCVVPWNKAENKFLCPCHGSQYNAQGRVVRGPAPLSLALAHADIDEAGKVLFVPWVETDFRTGDAPWWS
What is the function of this protein?
Essential protein for photoautotrophism.  Confers resistance to photo-oxidative damages by contributing to the thermal dissipation of light energy and to lumenal acidification (increase of pH gradient).  Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity).
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, chloroplastic, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, Proton gradient regulation protein 1, Rieske iron-sulfur protein, ISP, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: RL17_THEM4
Sequence: MRHRKNKHRIGRYGSHRRATLRNLSREIVEHQSIITTTKKAKAVKEYFEKLMTKAIKAKKAEKKEREVALRREIFKALGDRRLVNKLVDEIAPKYLDRQGGYTAIYKVGPRRGDGAEMSLIKLVIEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYI_THEAC
Sequence: MQSLRFRQIDPGMTLREIDSEILKYWKDKNILEKILSKGGSKKFVFLEGPPTANGRPHIGHAMTRTIKDIVLRYNTMTDHKIYRRVGGWDCHGLPVELEAEKHFGFHTKSEIVNFGVEKFNQYCRESIFRYIDEWKQVDDLIGFSIDHNGDYITLRNDYMESEWFALKTMYNSGLLYKDYTVVPYCPRCETSLSSHEVAQGYKDVKDPSVYVRFKSADEENTYFVAWTTTPWTLPSNEFLVVNPDMEYSLVEAQGSRYYVASSRAGYIFKEYREIRRMHGRDLVGKRYLQLMPFLDPPSGSLKVVAGSFVTSEDGSGIVHAAPAFGADDYQIGKEEGVEILNPVDKNGRFADPRIPWNGKFVRDANEDIIVYLKKNQMLLKSEKYEHSYPFCYRCDTPLLYYPLDAWFIAVSRIRDKLVEYNERINWKPDYLKHGRFGNFLGEAKDWNLSRDRFWGTPLPAWRCKNGHLVFVGSRKEIEDLGGKVPEDLHRPYIDEVRFKCPTCGEEMSREPYVIDTWFDSGSATYAASHYPFEKNFDPETDVPVSFITEAIDQTRGWFYVLHVIATIMFNKNAYESALSINFILDAQGRKMSKSKGNSVYALDFLNEVPPDSLRLFFLYGAPWKSKNLDKKVIDEVSRKTLMTVLNVYSFFAYNANIDNFQWNGLQLSGNALDRYMVSKVNSFVRSSRDAYESLDFHEVVRASMEFVDDLSNFYLRLSRRRFWAEGFDDDKLSAYSTLYYALKAFSEVMAPITPFFSDFIYLNLGGDKESVHLEAFPEFDSTLMDEKLESEMDRAYSVIETVRRLRQENSIKGRQPLREILIAGDMEESIIDVVKSELNAKDIKLIERDQEPIRLSADLRMDRAAPVLRSRVNAVRHKIRSMDGLEVQRQISEKGFVEIDGVRLDPDMVEISRVPDPNYAYSQTEKYGIDVFINKNIDRDGYLEGLARELVRRIQVMRKEMNLNYTDRIITHLDLSDDFLEALNKHAEYIKNETQSDSIITDKVEGMKLWEINGEPVRIKIDLAR
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDD_ECOL6
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPIGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SN114_YEAST
Sequence: MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGNNNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAHSIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSMEKDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFDNKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSESRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKGISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCSNESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGIMDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPILLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGFETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRRRKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP
What is the function of this protein?
Component of the U5 snRNP complex required for pre-mRNA splicing.  Binds GTP.
What are the official names of this protein?
Pre-mRNA-splicing factor SNU114, 114 kDa U5 small nuclear ribonucleoprotein component, Growth inhibitory protein 10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_MARN8
Sequence: MAPDILQAFMTEKTQNAPQSGKVGFISLGCPKALVDSERILTQLRLDGYDVVPTYDDADIVVVNTCGFIDAAKQESLDAIGEAISENGKVIVTGCMGVEADRIRETHPGVLAVSGPHAYEEVVGAVHQYVPPRKEHDPFLDLVPPQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGDVMDEAKRLVDAGVKEILVISQDTSAYGVDIKYRTGFWQGRPVKTKMQALCEALGEMGVWVRLHYVYPYPHVDDIIPLMAEGKILPYLDIPFQHASPRVLKAMKRPAHDSKTLERIRKWREICPELTIRSTFIVGFPGETEEDFQYLLDWLDEAQLDRVGAFTYSAVEGAPANELEGAVPEEVKEKRLARFMAKQAEISAARLQAKIGRTIDVLIDEVDEEGAIGRSKADAPEIDGMVYLNDETELVPGQIVQAVVEHADEHDLWARLI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_BRADU
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATKADNITTGRIYQDIITKERRGDYLGATIQVVPHVTNAIKEFVLDGNDDYDFVLVEIGGTVGDIEGLPFFEAIRQLKNDLPRDHAVYIHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDREIPKEERRKLGLFCNVRESAVIEARDVDNIYAVPEAYHNAGLDDEVLAAFGIASRIPPELRSWQQINERVRNPEGNVTIAIVGKYTGMKDAYKSLIEALSHGGIANKVKVNLDWIESEIFEKEDPAPFLEHVNGILVPGGFGQRGAEGKIRAAQFARERDVPYFGICFGMQMAVIEAARNLVGIEDANSTEFGPTKEPLVGLMTEWLRGNELEKRSQAGDLGGTMRLGAYPAALNRGSRVSQVYGGATEISERHRHRYEVNTAYKDRLEQHGLKFSGLSPDGVLPEIVEYEDHPWFIGVQFHPELKSRPFEPHPLFASFIQAAMVQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS1_HELPY
Sequence: MSKIADDQNFNDEEENFAKLFKKELEKEETLEKGTIKEGLVVSINENDGYAMVSVGGKTEGRLALNEITDEKGQLLYQKNDPIIVHVSEKGEHPSVSYKKAISQQKIQAKIEELGENYENAIIEGKIVGKNKGGYIVESQGVEYFLSRSHSSLKNDANHIGKRVKACIIRVDKENHSINISRKRFFEVNDKRQLEVSKELLEATEPVLGVVRQITPFGIFVEAKGIEGLVHYSEISHKGPVNPEKYYKEGDEVYVKAIAYDAEKRRLSLSIKATIEDPWEEIQDKLKPGYAIKVVVSNIEHYGVFVDIGNDIEGFLHVSEISWDKNVSHPNNYLSVGQEIDVKIIDIDPKNRRLRVSLKQLTNRPFDVFESKHQVGDVLEGKVATLTDFGAFLNLGGVDGLLHNHDAFWDKDKKCKDHYKIGDVIKVKILKINKKDKKISLSAKHLVTSPTEEFAQKHKTDSVIQGKVVSIKDFGVFINADGIDVLIKNEDLNPLKKDEIKIGQEITCVVVAIEKSNNKVRASVHRLERKKEKEELQAFNTSDDKMTLGDILKEKL
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: RNC_XANCP
Sequence: MSNRTFQRGDPIGHAFADPGLLAQALRHRSAGTPHNERLEFLGDGIVNLLIAEALYQRWPKADEGALTRARAELVREGALAVIGRTLNLGERLTLGPGELKSGGHRRDSILADAVEAIVAAIYLDCGFERCRAVVLPWFEPSLAALPVGKAEKDPKTRLQEWLQARQLPLPQYALISESGDEHAKQFHVACILEQPAARAEGQGTSRRLAEQQAAATVIAQLDSNT
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAB_TREPA
Sequence: MPGMPNPTQELKGKIPPHNLEAERAVLGAVLLDDSALSTATEQLSASSFYSAAHQRIFQALVELSDLGQRPDILVLSEHLRSCEALDFVGGSAYVASLTDAVPSAANVEYYTRIVCDAAMRRSLLKVARIITAEAFNDTVSGNIVLETAQREIYDLTNARRVATFKLLKNLIPDLVNTIETRYRNQSDLVGIATGLTALDNLTGGFQNSELIVIGARPSMGKTALAMTMASNIAIRQRIPTAFFSLEMSNLLLMQRLIAAESGVSATNLRKGLLQLSDFGRIQNAAGEMYDAPLYIVDVPNMKLLDLRAVARRLCVQEKIQIIFVDYLGLIVADNPFAPRYEQFAAISQSLKSLARELDIPIVALSQVGRPAEGSAPNLADIRGSGAIEQDADVVMFLHRDRNETETQLILAKQRNGPIGTVELEFQASFTRFVCKSP
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: SWA_DROPS
Sequence: MSLEDESFPADELFEQLNSASIGASRQFKSQFGEHDQPEAFERNPAPFLTSDCSDESSFIDAANKSAKTCVSDPVGLDQCEEEEEVDKDFEDSALANGNSELQIKSARSSKSVSYQDIHSAHTKRRYKHVTSKVAKYIADIHAQDQQRRNATKKFQRHSSMPEYLTPTARERGAHFSVDELHNLDESLDNSSAGNITDAKTPNDSYERLLSENERLQNDKEDLKSYSDYLQTKLDEKAMENMQLRRNFDVLRTDLTDCKEKLKRNQSYSLRSLNFCPPASVPKATQTDHELLSHAPNISRLSNMVAIADSGTPLPGSNTNNLTYDSSAGSIEVALLSVAPAARQPNAGKPKKNIQPHSLDFSNDSTEAEPNGNGTTSTGHSSSRAITSRRGAAPNNSESSHPSSNDSAIEVEALDLRSPYHRQPQGSIYPPMQDWGHSDGIYFFDKRNSRVIEVRSINVSQSSNPEQNSGTSETNLLNQSHVQFRHKRTSMGTRMLRLLGPCVRCTDTNQSVNASSATYTIGLPLLREEYGGRHTDR
What is the function of this protein?
Has a role in localizing bicoid mRNA at the anterior margin of the oocyte during oogenesis, and a poorly characterized role in nuclear divisions in early embryogenesis.
What are the official names of this protein?
Protein swallow.
What are the subcellular locations of this protein?
Nucleus. Note=Uniformly distributed in eggs, becomes localized to the nuclei during early mitotic divisions in early embryogenesis. Swallow enters each nucleus at the beginning of mitosis, occupies a position complementary to that of condensed chromatin, and leaves each nucleus at the end of mitosis (By similarity).
Protein: RF3_HYDCU
Sequence: MSLQLETNKRRTFAIISHPDAGKTTVTEKLLLYGGAIQMAGAVKSRKTDRSATSDWMKMEQERGISVASSVMQFPYKDVMINLLDTPGHEDFSEDTYRTLTAVDSALMVIDVAKGVEDRTIKLMEVCRLRDTPILTFINKLDREGKEPIELLDEVEDVLKINCAPMTWPIGMGKRFKGIYHLYNDTVRLFESADGLNASEGELIHGLDNPELDQKLGSLAEELRDEIELVRGASHEFELDAFLKGTMTPVFFGSAVNNFGLQELLDGFAKYAPAPEGREASTRFVKSDEGKLTGFIFKIQANMDPKHRDRVAFMRIVSGKYEKGMSLKHVRIGKDVKIAKAITFLANKRDQAEVAYPGDIIGLHNHGTIKIGDTFTQGEDLKFTGIPNFAPELFRRAQLKDPMKMKALQKGLTQLSEEGATQLFRPIINNDLILGAVGILQFEVVAQRLKDEYNVTCLFEPVNVSTARWVIGDKAEIDKFLAKVKENVAYDAAGELVYIAPTRVNLTLIEERWPELQFVATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_CITK8
Sequence: MNTTLAQQIANEGGVEAWMVAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVGFSEETFARIREDYLTFAGQLPGNRDIRFVPLSALEGDNVATQSASMPWYNGPTLLEVLETVEIQRVVDTQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGQRIKVLPSGVESNVARIVTFDGDLQEAHAGEAITLVLKDEIDISRGDLLLDAGENLPAVQSAAVDVVWMAEQPLSAGQSYDIKIAGKKTRARVDAIRHQVDINNLTQREVESLPLNGIGLVELTFDEPLVLDTYQQNPVTGGLIIIDRLSNVTVGAGLVREPIEHTAATPSGFSDFELELNALIRRHFPHWGARDLLGGK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: KGUA_YERPE
Sequence: MVQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEFCQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEMAHYAEYDYLIVNDDFNLALSDLKTIIRAERLRLGRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLCTK_HUMAN
Sequence: MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALSLDPGGRQLKVRDRNFQLRQNLYLVGFGKAVLGMAAAAEELLGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTRLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVVSLILSDVVGDPVEVIASGPTVASSHNVQDCLHILNRYGLRAALPRSVKTVLSRADSDPHGPHTCGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSMAGASVEEDAQLHELAAELQIPDLQLEEALETMAWGRGPVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAGAWVTPELASQAAAEGLDIATFLAHNDSHTFFCCLQGGAHLLHTGMTGTNVMDTHLLFLRPR
What are the official names of this protein?
Glycerate kinase, HBeAg-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-2 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion.
Protein: RS14Z_ACET2
Sequence: MAKKSLIVKQQRKPKYRTRAYNRCKLCGRPHAYMRKFGICRLCFRDLAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.