PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_KLEP3
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAATNQSLPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHISQNVAQVSETRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CPFC_LACP3
Sequence: MAKGLLIVNLGSPVSPETKDVRRYLREFLSDQNVITMPKALWQPILRGFILPFRSWRSATFYKHEWTQAGSPLIAYTQVTRDRLRERLPDWDVQMAMNYGGEYPIGETLQTMAARGDAPIVVIPLFPEYTQSTTKTILDKVAASGVKTVVIDRFYDHSDYQKILAQQIDDAYEAGAYDTVILSYHGIPTAMVRHGDPYQQECETTTAGVKQYLKKVPQTKVEMCYQSKFGPVPWLKPYLRNRLMELAALGKRNVLVATPSFVADCLETLEENNVQNYQTFRANGGKNFATVRPMNGCEPFCDFLAKLAEDKIAAEANHGKA
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_VIBPA
Sequence: MDQFQHIDVQGAQALLEQGEAKLVDIRDPQSFAVAHAESAYHLTNDTIVAFMEDVEFEQPILVMCYHGISSQGAAQYLVNQGFEQVYSVDGGFEAWQRAQLPIVRS
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_SULIL
Sequence: MSILSLVGLGISKKFITENAIDTLNNSDIIIFDKYTSRSCDINVDVLRRLVKGGKTLIEADRSLLENNSKIIMDYLDKNYNVSIASIGDVLIATTHVSLLIEAKQRGHNVKVIPGISVHCYLISKSLLSSYKFGKSVTVTFPYNDFIDPTPYNVIKDNKERGLHTILYLDLKSEKAMTANEALQILLRLEDKHRKNVLSKSDIVIVGARLGCDDEKIVALTVEEATLYDFGNTPHIIIIPGNLHYMEADAIKWMLMS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RL27_ESCF3
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LUCI_NIPCR
Sequence: MENMENDENIVVGPKPFYPIEEGSAGTQLRKYMERYAKLGAIAFTNAVTGVDYSYAEYLEKSCCLGKALQNYGLVVDGRIALCSENCEEFFIPVIAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTTIKTIVILDSKVDYRGYQCLDTFIKRNTPPGFQASSFKTVEVDRKEQVALIMNSSGSTGLPKGVQLTHENTVTRFSHARDPIYGNQVSPGTAVLTVVPFHHGFGMFTTLGYLICGFRVVMLTKFDEETFLKTLQDYKCTSVILVPTLFAILNKSELLNKYDLSNLVEIASGGAPLSKEVGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPSIFDAGVAGVPDPVAGELPGAVVVLESGKNMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGRAIREILKKPVAKM
What is the function of this protein?
Produces green light with a wavelength of 544 nm.
What are the official names of this protein?
Luciferin 4-monooxygenase, Luciferase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HDA22_DICDI
Sequence: MSTNNIIEGDEDTKTTITNESNTDNNNNNNDDNKNNTENTTSPTNNNNTNDNDNNSDNNNNKNNNNNNSQVTEEQQVTLEDSGSEDDINFEEHELSDSAEEDEDEMEDDDEDADGRQNQNPNSAGGKRRGRPSKVQQSTNTHLSQTTPESPTIFTPDGKVPKRISTSTNNTPNTQSALKTNKRPRLTSDEEKDLMLSEESDGGVGEDDDSIMSTNDKPQDENQSNQNQNNNNNNNNNTTTTTTTTNNSNNNNQNLNQNNNNNNNNNNINNNNNNNNSNNDNNNNNNRPARGRPKTNGSRSEERKRIQLQQYIQATQGSSTTTSDPNNQNNQINQINQNNQNNQNNQNNQNNSLGEEEFGEEFEEEEEDMGQPKKKTKYKTSKKSVPNHLDIRPCWFVGCVKADRSLKILRPCLIPTCKTHAIKSEVRISEALRRGDFVNDESSGVKDKVCGICGDKKDLHHCGNNGCAFGFCNDCVEIAAMKHNNHPNGNKWICWVCQFVRTKAKEKERTRWVKEQLNPGLTSISRKFRRGPELDMAQAQFLQQQQQQQTSPNEKRSSQFNSNNSNNNNNNNSNNNNNNSGFDPSGSPNNQQNQKRLRKKINASSDIYETRKYTKKRNDEDSAPPSPTSIIGNSVMVGSSGAAGGGIIKNTTVVVEQQGYSATPPSPNTLMVQQQQQLQQTHQQARLSQQQAQLQQLKALQQQHQHQQQNNGNFNNLIESVLSPNREPLNPIDNFVDQTFTAVKFFSTLSQNPPDEIKERIDNFVDLMMRIKTVRWASDYGLVWRMIEELSNLIKRNLLSSQSVVEMYSELKSLEEGALENMTTNARNVPLERAITMVFENHETAGLIGKECCSTRNALIYSIEVALRAIADYQHDLEDNLMEESLRSNKVSTEIEQIEHQIKANLDEIHKFKYQEVELLDSLSKVRGAIAAHESIRDTLQKKSSELKVDMLLIKNGISDKEKETKSQQATLENEIYALKLLITMVESIYWIHDYFYESRVGECEKLINNKLSQLQNKLETQIPHPPNALDNAIPNTTTTVMGEDGQPVIVPTTVDIKNKFKTIAIYHKICMQHKVPNFHLEKPDRIQVAVSCINEFASNPLVDIFDNPPEVDMRYVMAVHDANYIKKLETSLPPENSEFETHLESDKSGAMVTVASHKDFEGDDDNIYDTFVSHRSIKAALRASGSVCAAVDSVSRSGYTRAFCAIRPPGHHAGRYGRTSDAPSQGYCLINNVAIGAKYASLTAGYSRIAVVDFDVHHGNGTQEILSGDDNFLFISIHVCDEKRYFYPGTGQDVGDIDEVSGQFDGNILNIGLKRNTGSAVFLQQWMNKIIPRLEAYKPQLIFLSAGFDGHKDDPTNGLKLNEEDYFVITKMIKTVAFKYCKGRIISVLEGGYGIEKTNSLQRCVNSHLKALIEDTDEEIHLANISYGHFSETQETAIPKFNINNFISNPNKRGKKNNLNTINFINNNMNNINNNITNSLSNKQLERQKQLQQQQQQAQQAQQQQSPQQSQTIENTSITTTTTTTSTTTTLSTSDSESNNNINNNNNDYNNNNNNNSNNNNNNSNNNQPTNFNSSTSSPILSGNNNNNNNNNNNNNNNNINNNNNNNSNNNNNMNTSNPTNQQSSVIISDDMDDVQTNSNPPNPQYPLSPNSVNRGNNPSNISMSGAQRSAPLIISPKPSNSPNSPSTSNNNGTPQNINNSDN
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Type-2 histone deacetylase 2, DdHdaC.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HGLS_ECOLI
Sequence: MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVLENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQAGVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCRQLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFPGCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLFAGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFPDSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVSAAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL
What is the function of this protein?
Catalyzes the decarboxylation and hydroxylation of 2-oxoadipate (2OA) to form D-2-hydroxyglutarate (D-2-HGA).
What are the official names of this protein?
2-oxoadipate dioxygenase/decarboxylase, 2-hydroxyglutarate synthase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.
Protein: TPS2_CANSA
Sequence: MHCMAVRHFAPSSSLSIFSSTNINNHFFGREIFTPKTSNITTKKSRSRPNCNPIQCSLAKSPSSDTSTIVRRSANYDPPIWSFDFIQSLPCKYKGEPYTSRSNKLKEEVKKMLVGMENSLVQLELIDTLQRLGISYHFENEIISILKEYFTNISTNKNPKYDLYATALEFRLLREYGYAIPQEIFNDFKDETGKFKASIKNDDIKGVLALYEASFYVKNGENILEEARVFTTEYLKRYVMMIDQNIILNDNMAILVRHALEMPLHWRTIRAEAKWFIEEYEKTQDKNGTLLEFAKLDFNMLQSIFQEDLKHVSRWWEHSELGKNKMVYARDRLVEAFLWQVGVRFEPQFSHFRRISARIYALITIIDDIYDVYGTLEELELFTKAVERWDAKTIHELPDYMKLPFFTLFNTVNEMAYDVLEEHNFVTVEYLKNSWAELCRCYLEEAKWFYSGYKPTLKKYIENASLSIGGQIIFVYAFFSLTKSITNEALESLQEGHHAACRQGSLMLRLADDLGTLSDEMKRGDVPKSIQCYMHDTGASEDEAREHIKFLISEIWKEMNDEDEYNSIFSKEFVQACKNLGRMSLFMYQHGDGHASQDSHSRKRISDLIINPIPL
What is the function of this protein?
Involved in monoterpene (C10) olefins biosynthesis.  The major product is (+)-alpha-pinene.
What are the official names of this protein?
(+)-alpha-pinene synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTL26_XENLA
Sequence: MLVATAADRNKDPILEVLRQYVDPAAPKVRALEVASGTGQHCAHFARALPNLYLVPSELDPRSLQSISAYISHWSLSNVEQPRTLDVSKSWETWGFKPNSLQLIICINMIHISEPSCTQGLFKGAGHLLQPGGVLFTYGPYSVNGILTPQSNVDFNLSLKSRNPAWGVWDTSDLQNLATACGMSLERMVDLPANNKCLIFRKK
What are the official names of this protein?
Methyltransferase-like 26.
What is the protein family that this protein belongs to?
Belongs to the UPF0585 family.
Protein: E1A_ADE05
Sequence: MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPDSVMLAVQEGIDLLTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPSDDEDEEGEEFVLDYVEHPGHGCRSCHYHRRNTGDPDIMCSLCYMRTCGMFVYSPVSEPEPEPEPEPEPARPTRRPKMAPAILRRPTSPVSRECNSSTDSCDSGPSNTPPEIHPVVPLCPIKPVAVRVGGRRQAVECIEDLLNEPGQPLDLSCKRPRP
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E1A protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes and of the E2 region of the adenoviral genome.  Release of E2F1 leads to the ARF-mediated inhibition of MDM2 and causes TP53/p53 to accumulate because it is not targeted for degradation by MDM2-mediated ubiquitination anymore.  This increase in TP53, in turn, would arrest the cell proliferation and direct its death but this effect is counteracted by the viral protein E1B-55K.  Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection.  Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF(FBXW7) ubiquitin ligase complex, and may be linked to unregulated host cell proliferation.  The tumorigenesis-restraining activity of E1A may be related to the disruption of the host CtBP-CtIP complex through the CtBP binding motif.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta) (PubMed:26405230).  Promotes the sumoylation of host ZBED1/hDREF with SUMO1 (PubMed:25210186).
What are the official names of this protein?
Early E1A protein, Early E1A 32 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1A protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RS17_MYCTO
Sequence: MAEAKTGAKAAPRVAKAAKAAPKKAAPNDAEAIGAANAANVKGPKHTPRTPKPRGRRKTRIGYVVSDKMQKTIVVELEDRMRHPLYGKIIRTTKKVKAHDEDSVAGIGDRVSLMETRPLSATKRWRLVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: G6PI_BORPA
Sequence: MPTPLPSSSAWLAFADAARHSSRRGARLRVIEAAGLRVDLTAQAHSDDLDSAAEDLLAQQDFDNARAQLFDGGPANWTEHRPAWHTALRAARPPTPVAGAILGERDRLRRFVQDADMRGAYRHVLHLGIGGSDWGPRMVTRALRHNGLKREVRFASNVDSHAVADALHHLDPHDTLIIVASKSFTTTEPLANAEVAMNWLRNAGVADPVRQVVAITANVDAALDFGISPQHIFRFWDWVGGRYSLWSAIGLPVALALGCDALDELLAGAAAMDQHFLHTPMRRNAPLQMALAGVANRSVLGYGSLAITPYDSRLTHLVPWAQQLEMESLGKVAGHDGSPAGVPTGPVVWGMTGTDCQHTFFQWLHQDTAGAPVDFIVCEQADHPYDHFHKLLIANCLAQRAALLRGKPFDEALKEARLVESDPQQAEILAHHRVHPGGRPSTLIMLPRLSAHALGALLAMYEHKVFAQGVLWGINPFDQWGVEYGKALARNIIRELENPSSEVNQQDPSTRYWIDALRKQP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_LYCRE
Sequence: SLSDKDKAAVKAIWNKISKSADVIGADAMGRMLVVYPQTKTYFSHWSDLSPNSAPVKNHGKTVMTGVALAVSNIDDMTTGLKALSEKHAFQLRVDPSNFKILSHCILVVIAMMYPKDFTPEAHVSMDKFFCGLSLALAEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TPIS_SHEPA
Sequence: MALRRPMVAGNWKMNGSAQLAQELFNKFATKLQDDSVEVVLCPPSIYLESVRQLLDENKETLNGCLVRMGTQNLSQHDFGAYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLIGGVSLNATEFLSLCTIAMSA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG22_HUMAN
Sequence: MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis.  Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state.  Inhibits RAC1-dependent lamellipodia formation.  May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity).
Protein: RL28_STRA3
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTVLIDGKPKKVWVSARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: YIDC_BURMA
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRSHGRPSMFFPNVTQTNTASNATNGNGASGASAAAAANALPAAATGAAPATTAPAAQAQLVRFSTDVYNGEIDTRGGTLAKLTLTKAGDGKQPDLSVTLFDHTANHTYLARTGLLGGDFPNHNDVYAQVAGPTSLAADQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIENVGAAPVTPSVYMELVRDNSSVETPMFSHTFLGPAVYTDQKHFQKITFGDIDKNKADYVTSADNGWIAMVQHYFASAWIPQSGAKRDIYVEKIDPTLYRVGVKQPVEAIAPGQSADVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGFVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWVLWIHDLSQRDPYFILPVLMAVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRTLGGAAAKKKAS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACDH_MYCGI
Sequence: MADKLSVAIVGSGNISTDLLYKLLRSEWLEPRWMIGIDPESEGLARARKLGLETSHEGVDWLLARDEKPDMVFEATSAYVHRDAAPRYAEAGIRAIDLTPAAIGPGVIPPANLREHLDAPNVNMVTCGGQATIPMVHAVSRVVDVPYAEIVASVSSASAGPGTRANIDEFTKTTSAGVEVIGGARRGKAIIILNPADPPMIMRDTIFCAIPEDADHAAITQSVKDVVAEVQTYVPGYRLLNEPQFDEPSVVNGGNHLVTIFVEVEGAGDYLPPYAGNLDIMTAAAAKVGEEIARERVATSTTGAQA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RBFA_NEIMA
Sequence: MRKPQRGYARQDRVKEQIMRELAELVRTGLKDPRAGFITVNEVEVTRDYSHATVFYTVLNQDAREITEEVLEHARGHLRSELAKRIKLFKIPELHFKYDESLERGLNLSALIDQVAAEKPVED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPTC2_CAEEL
Sequence: MSRRTDSLCLDEYLSSELKKRTHILECAWNQEHDDDEEEEEVKVDQGSEETTSSHDIYGDVGKRAPNEFEKIDRLTTIKVYIAWLALFVFAHIREYVTRFGFVKDLSSKENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEYPGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLVAEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHNDMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYLDEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASPTGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGSNDSPVVPMLIYFPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDEVLETVNLLGSMSRSKFSKRSHLYKNQKIEW
What is the function of this protein?
Component of the serine palmitoyltransferase (SPT) that catalyzes the first committed step in sphingolipid biosynthesis, which is the condensation of an acyl-CoA species and L-serine.  The catalytic core is composed of a heterodimer of sptl-1 and sptl-2 or sptl-1 and sptl-3 (By similarity).  Required for the specification of abicobasal polarity and development of the gut lumen.
What are the official names of this protein?
Serine palmitoyltransferase 2, Long chain base biosynthesis protein 2, LCB 2, Serine-palmitoyl-CoA transferase 2, SPT 2, SPT2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: TIG_FRATM
Sequence: MQVTVEKKEGIHCSLLIEVPANEIDSVVSKEINRTAKTIKMDGFRPGKVPAGMVKKKYGEQIRMEVISDLIPQKYSKAIQDEKLAVAGIEVELKENKEGQPLKFVANLELFPEFEVTGFEKIEVQKPVVELTDKEVKQMIENLRKQFATFSEVDKVVEKDDKVTIDFVGKKDGEAFEGGTANDIDVIIGSGQMIPGFEDGIIGMKKGEQKTITVTFPQDYQNKDLAEAETTFDITVKKIQQAELPEVNDEFVKKFGVKGGVDTFENEIKENMQRELKFILQRKVKDQVFKGLREIAEFETPKSLIKREIDAAKQNLLKQMGGAKGFDVNQLPDNLFEANAKQKVETSLILDSIMNLQEFKAEEAEVESLLDELVQAYEEPEKTKEQIKKNDKEIANLKALVIENKLTDWVLEQAKVTEKTEDFFEVIKENMQAQQAGF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RNPA_PSEPF
Sequence: MSQDFSREKRLLTPRHFKAVFDSPTGKVPGKNLLLLARNNDLDHPRLGLVIGKKSVKLSVERNRLKRLMRESFRLHQDSLVGWDIVIVARKGLGDVENPELIQHFGKLWKRLARNKPVPAVKTETVGVDSPDA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: EFPL_ECOLC
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: TRMA_SHESW
Sequence: MNLAAMDPQTYDAQLEHKRIKLEQAFAQFETPSVEVFASEPANYRMRAEFRMWHDGDDLYYYMFDKVLNEKVRCDQYLPASVLINQMMSALIAELKPNPSLRHKLFQVDFLSTLSGEILVSLLYHRQLDDQWRTNAAALKAKLSSQFNVNIIGRARKQKIDLDKDFVVESLQVNDKTFLYKQIENSFTQPNAKVAVKMLEWAIDVTQDSQGDLLELYCGNGNFSIALAQNFNRVLATELAKPSVEAAQYNIEANGIKNLQIIRMSAEDFSDAMAKKRSFRRLEGIDLDSYVCNTIFVDPPRAGIDPDTLALVQGYERILYISCNPDTLKDNLEQLYKTHRVTQFALFDQFPYTDHMETGVLLERR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: Y4236_MYCA1
Sequence: MARTDDDTWDLATSVGATATMVAAGRARATRDGLIDDPFAEPLVRAVGVDFFTRWAAGELDAADVDVPGAAWGMQRMTDMITARTRYIDAFFAEAGAAGIRQVVILASGLDARAYRLPWPAGTTVFEIDQPRVLEFKAATIAQLGAEPTAPVRAVAVDLRHDWPSALRQAGFDVGRPAAWAAEGLLGFLPPQAQDRLLDNVTALSADGSQLVAEVFANTGASGDALNAAGEKWRRHGLDVALDDLGFPGERNDPASYLQQLGWQPVRTPLNQMLANNGLPLQSTEPGAPFAQNYYCTAVLNKAG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4236.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.