PharMolix/UniProtQA huggingface dataset:
Protein: IFNG_PHOSU
Sequence: MNSTRCILALLLCLTQAMSGCYGQGSLIEEIENLKEYFNSSSLDVGKGGDLLFNILMSWQKDGDTKIIESQIVSFYFKLFEALKGNQAIQRSIDTIKADLFVKFFNSSMEKLNDFVKLTKIPVNDPQVQRKAVNELLSVMPHLSPKLSLRKRKRSRCCFGGGNRPVKNNLASTI
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPC_STRMK
Sequence: MSDILQTILARKAEEVAQRRAQRPLEELQAAVASAPPVRGFVRALQAAVANGDPAVIAEVKKASPSKGVIRPDFRPADIAVSYEFGGASCLSVLTDVDFFQGADAYLQQAREACTLPVLRKDFVIDAYQVYEARVLGADCILLIVAALDDTQLATLSELALSLGMDVLVEVHDIDELERALQVPAPMIGINNRNLRTFEVSLQTTLDMQQAVPRDRLLVTESGILGLQDVALMRDAGIHAFLVGEAFMRVEEPGEGLRQLFFAA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ST1C1_RAT
Sequence: MSLEKMKDLHLGEQDLQPETREVNGILMSKLMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPSPLNSGLDLANKMPSPRTLKTHLPVHMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIEQFKAGKVLWGSWYDHVKGWWDVKDQHRILYLFYEDMKEDPKREIKKIAKFLEKDISEEVLNKIIYHTSFDVMKENPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRRKMAGSNITFRTEI
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters.  May be involved in the activation of carcinogenic hydroxylamines (By similarity).
What are the official names of this protein?
Sulfotransferase 1C1, ST1C1, HAST-I, N-hydroxyarylamine sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_NEIAN
Sequence: SIINMDGSHKQEDLEVISTGSLGLDLALGVGGLPRGRVVEIFGPESSGKTTLCLESIAQCQKNGGVCAFIDAEHAFDPIYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGVDMVVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGHIKRTNTLVVFINQIRMKIGVVYGSPETTTGGNALKFYASVRLDIRRAGQIKKGDEILGNETKVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKHDIIDKSGAWYSYNDTK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ACTSZ
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASALVSHEIIKTTLPKAKELRRVVEPLITLAKEDSVANRRLAFARTRNVETVAKLFNELGPRFAQRAGGYTRILKCGFRAGDNAPMAYIELVDRPEVSTETATTE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HOA2_MYCA9
Sequence: MTQLYIQDVTLRDGMHAIRHQISPTAVARIASALEAAGVNAIEVAHGDGLAGGSVNYGPGSNTDWEWIEAAADAVTTAKLTTLLLPGIGTVAELKRAYSLGVRSIRVAAHCTEADITAQHITMARELGMDVSGFLMLSHMASAETLAEQAKLMETFGAHCVYVTDSGGRLTMPMVRDRVRAYRDVLDSHTEIGIHAHENLSLSVANSVVAVEEGATRIDASLAGHGAGAGNCPLEAFVAVADLHGWGHSCDLFALQDAADDLVRPLHDRPVRVDRETLTLGYAGVYSSFLRHAEAAAQRYDVDVRSILIEAGRRRLVGGQEDMLVDIALSLST
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: NECP2_HUMAN
Sequence: MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGSTSSQTQPGTGWVQF
What is the function of this protein?
Involved in endocytosis.
What are the official names of this protein?
Adaptin ear-binding coat-associated protein 2, NECAP endocytosis-associated protein 2, NECAP-2.
What is the protein family that this protein belongs to?
Belongs to the NECAP family.
Protein: RUXG_YEAST
Sequence: MVSTPELKKYMDKKILLNINGSRKVAGILRGYDIFLNVVLDDAMEINGEDPANNHQLGLQTVIRGNSIISLEALDAI
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein G, snRNP-G, Sm protein G, Sm-G, SmG.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GEM1_CANGA
Sequence: MTKETIRVVICGDDGVGKTSLIVSLVKGQFIPNLQAVLPPVTIPRDFSSSPYSPKNTVLIDTDNSDPLAIQRELKNADVIWLVYSDKDSYERISLYWMITFRSLGLNIPVILCKNKCDQYTTNSPLEDFLDTKIEDEEFIPILMAFKEVDTCVKASAKTHFDVNQSFYLCQRSISYPISPLFDAKVGDLKPSAVAALSRIFFLSDEDQDGFLNDNEIMDLQRKCFGKSIDLNELNFIKHTLSDLTSSEEYPSEILYCQGKGLTKQGFIALNKIYTEKGRHETTWGILRAFNYTDSLSIDDAVLFPKVNVPEQASVELSSKGYRFLVDIFIKFDSDNDGALNDTELHTLFRSTPGLPNLWLETNFPASTVVNAKGFVTLQGWLAQWTMTTYLDYKITTAYLVYLGFQEDAKLAVQITKSRRMRRRQGRLYRSYVTDRKVFNCFVVGKRNSGKSSLLESFLGRLFSEAYSPTIRPRVAVNNVEVTGDKQYYLILQEFGEQEEAILQNPSRLAECDVLCLTYDSSDPESFSYLLELLTNNEIMKDIPVVFVALKADLDKQQQRCKFQPDEFTDTLYLDHPLHVSSTWSSSLNQLFKKIIQASLEPGKFTPGFPPDIKPTNIDYSSAVILGSSIGFLALFSYTMIKLLKPTQQ
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
What are the official names of this protein?
Mitochondrial Rho GTPase 1, GTPase EF-hand protein of mitochondria 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: TPPC2_CHICK
Sequence: MSGSFYFVIVGHHDNPVFEMEFLPPGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFAFVLHMRFIMLHDVRQEDGIKNFFNDVYDLYIKFAMNPFYELNSPIRSSAFERKVQFLGKKHLLS
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasm. Note=Localized in perinuclear granular structures.
Protein: RS20_BOVIN
Sequence: MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDAP2_DANRE
Sequence: MDPLGARSQFVEVLNLPTWDQPQGVQDELDGENHYEEEEEEEEDNLTNQLNSVNSPFTFRQDINNKIVLFNGDVALLNCTAIVNTSNETLTDKNPISDSIHRHAGPELRDELLKLKGCRTGEAKMTEGFDLAARFIIHTVGPKYKAKYRTAAESSLYSCYRNVLQLAKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVRRFLENHGENIETLVFAVSDVEEPVYRKLLPLYYPRSKQEERISLPLLPADIGNSEGEPVVPERQIRIAEKPVNLEDDPEDDSLDSDLGLVGSHAFARMEGDVDKQRKLILQGQMSEVAQQKQHQRNYNRWLCKARAEDLSDIAALKALYQTGVDLCGRTVMVVVGRNIPVMLIDMEKALLYFIHVMDHITVKEYVMVYFHTLTGEHNHLDTDFLKKLYDIVDAKFKKNLRAFYFVHPTFRSKVSTWFFTTFSVSGLKDKVHHIENLQQLFTCVLPEQIDIPPFVLEYDSRVNSPYYSAQSAGL
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the GDAP2 family.
Protein: GET1_ASPOR
Sequence: MLSLIWTIFFLHVAIYVVNTAGASTIDSLLWLLYLKLPTSTSKNAREQSRLKREALELKRDMNNTSSQDEFAKWAKLRRRHDKTMDEYEQLNKTLTAQKSSFDWSVKIARWLSTNGLKIFLQFWYSKTPVFALPEAWIPYYVQWILSFPRAPMGSVSVHVWNSVCATAVSVTAEMVTSMFLQTARPTPVATAQKTQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL36_STRPD
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ENV7_YEAST
Sequence: MISIVLELFQNLCCCRGFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQSPYVIKSIDSQVMQEKDGSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLNLLQDLDT
What is the function of this protein?
Serine/threonine-protein kinase involved in vacuolar processing and morphology.
What are the official names of this protein?
Serine/threonine-protein kinase ENV7, Late endosome and vacuole interface protein 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: RL4_OCEIH
Sequence: MPKVALLKQDGSNVGDIELNDSVFGIEPNTHVLHEAVVMQRASLRQGTHAVKNRSEVRGGGRKPWRQKGTGRARQGSTRSPQWVGGGTVFGPTPRSYSYKLPKKVRRLALRSALSSKVNEESLLVLENISIDAPKTKEIVNILKGLQVDAKALIVLSEKDETVIRSANNLQNVTVLTVEELNILDLLMHDKLIITKDAAEKAGEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: OCTB3_DROME
Sequence: MSGVNVADLLATTMTLPITAAAGAATSQAAATSATNASHLQPATLTGHISTTAAAKTTTTPTSSLPITSQFVDASLTSLSLTATSSDASYSSPFSSYLSSDSTFELLSTVGPNITANGSDIAVDNQAELEESWLDLSLLLLKGFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALISFTPIFLGWYTTEEHLREISLHPDQCSFVVNKAYALISSSVSFWIPGIVMLVMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREETHSALSNLEDMLQPATDEDDDRDECDELRVPSPPPRRLSRSSIDLRDLEQERYEKVTHTDSAPSMMALQQQQPSHNQLQPPAPVFNPQIWTEGKMIPSKELDKEHSHPNGPQQQLSLTSGSGNSEPEPESTAYRVFGGLNSDESEGNDLYDTHLPLAEDNKELKRLIEDNYLYFKRQTGGTIISGPGGGKYAALSETDFIRLKAGAAACGRKAFASSDSEFLRTISESRALPEQPVPGKEKGFNILSLLSKTKRSSTECFTLEKKRHQANSEGSSFFRRSRNRKLSHSYNGCGGGKERKLERRQRQHSDTDSTPNKPDILLDINVLSEQSGASVIQQFSDGVQLIDFSELKTPPERIRSDDELAQLADCFGESPQQPATPPPSLSPPELPEPSGLLIASSSELAEIFRSLSFPLGRPAGAPQRLSTLSDQVCANYLMSPPNTPAPPAISVPNGGAMDSSASSNAQSASINVYFLSPPPHAAAPGYTPSDTSTVSLDVVTSLPMPVPVPQPNPQMASQSNISPKPEIILDSTLSPVEGCGDEHRDVTSPLFKRKDSAGDADVSVSGNGGAGGVGGVGGRQGRCSILAGYDGIQTVRKRQASVVTYDVNVINFSQENSDSRSYIPMGRVSTSSAKHEFSNKSSLIRRGGICIFVDEEEAEIIEQRPRGITFAAVPSPLPKCPLCGADISSTTGTTANATATANADSTIDTTVTTSSKRSIHEQTPDLGQRPASSSSSTRFWHKRTAAVTACWQQSKNRKRRFKTGCSHCGATGGSVRPAKGWKAEHKAARTLGIIMGVFLLCWLPFFLWYVITSLCGPACPCPDVLVVVLFWIGYFNSTLNPLIYAYFNRDFREAFRNTLECVLPCLEKRNPYNAYYV
What is the function of this protein?
Autoreceptor for octopamine, which is a neurotransmitter, neurohormone, and neuromodulator in invertebrates (By similarity).  Probably also acts as a receptor for tyramine during ecdysone biosynthesis (PubMed:25605909).  Required for the biosynthesis of the steroid hormone ecdysone which is necessary for metamorphosis (PubMed:25605909).  Involved in activation of prothoracicotropic hormone and insulin-like peptide signaling which is required for the expression of ecdysone biosynthetic genes (PubMed:25605909).
What are the official names of this protein?
Octopamine receptor beta-3R, DmOct-beta-3R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAN_HUMAN
Sequence: MGAPFVWALGLLMLQMLLFVAGEQGTQDITDASERGLHMQKLGSGSVQAALAELVALPCLFTLQPRPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVRVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAERFDAYCFRAHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTLEEEEVVTPDFQEPLVSSGEEETLILEEKQESQQTLSPTPGDPMLASWPTGEVWLSTVAPSPSDMGAGTAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAVNQMEPPLAMAVTEMLGSGQSRSPWADLTNEVDMPGAGSAGGKSSPEPWLWPPTMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEATVSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSLPLSLTPTGQGGEAMPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGIPGSESGVFDTAESPTSGLQATVDEVQDPWPSVYSKGLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPHPEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPSSTLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPALPGTPMNAGAEEVHSDPCENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVCTKPRRSHRMRRHHHHHQHHHQHHHHKSRKERRKHKKHPTEDWEKDEGNFC
What is the function of this protein?
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM).  Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
What are the official names of this protein?
Neurocan core protein, Chondroitin sulfate proteoglycan 3.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROE_THESQ
Sequence: MKFCIIGYPVSHSISPRLYNEYFKRAGMNHSYGMEEIPPESFDTEIRRILEEYDGFNATIPHKERVMRYVEPSEDAQRIKAVNCVFRGKGYNTDWVGVVKSLEGVEVKEPVVVVGAGGAARAVIYALLQMGVKDIWVVNRTIERAKALDFPVKIFSLDQLDEVVKKAKSLFNTTSVGMKGEKLTVSEASLKGLYLVYDVVYFETPLVSDAKRLGVEHVVKGNLMFYYQAMENLKIWGIYDERSFKEVFEEVLR
What are the official names of this protein?
Shikimate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL13_STAAE
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TO1B_HADMO
Sequence: MNTATGVIALLVLATVIGCIEAEDTREDFQGGFESDDGEAAEKIFRRAPVCTRTDQPCPYDQDCCSGSCTLKKNENGNLVKRCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hmo1b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KSL4_MAIZE
Sequence: MASLSFASSHASLFCCQQSSSAIILRPAGALLRLSRRQPSSHTISTTDQLFPRRSRMPRNVDTHAAAERNSPSTMSSLEAVDELETNGDSAVVVVREQQQQQHLLMGATDDGLPPSPYDTAWVAMVPAPGNPLVPRFPQCVDWILQNQRSDGSWGPDGGSGDHPSSPLGKDALMSTLACVLALKTWDAGEEHVRKGLSFVGNNSPSCVMTGDERDAPVGFSVIFPGMLARAIDMGLDIPMMTQANVDAFIRLRDTELNRMAATTGSKAFMSYVAEGLGDVLDWDEAAMVYQRQNGSFFNSPATTAAAAIHGNNDRALRYLDSLVNMFGSSVPTVYPRSTYSRLHMVDTLQKMGLSRSFVSEINEMLDMTYRSWLANDDEEMMLDMSTCAMAFRLLRMHGYDVSSDGLAQFSSESSFRDSVHGQANDTEALLELYKASQIQITEDELVLVDIRSWSAKLLKEQLGSDKVSRSVDAQEVQQVLKFPFYTTLDRLEHRRHIEQFKAGGFHMLKSAYRFCKEDEELVSLAVQGFHSSQALYQQELQFLTRWAKEARLHDLEFARIMPMNTFFPNAALMYAPELSEARILCTKNCMLATAVDDLFDVGGSREEMENLVRLIDMWDEHEEVGFCSERVEILFRAIYDTSKELAAKAMAVQNRSVINHVAELWADLVRAMMTEAEWSMRGHVPSSMEEYMQVAETSFALGPIVLMPLYLIGPELPEAVVRCPEYKQLFHHMNVCGRLLNDLQSYEREAKQGKINSVLLVAPRHGGSIEAAKSEVRRAIEASRRELLRMLVAEADATVPRPFRQEFWNMCKMVHLFYMEDDCYSSPKELVHAANMVVFDPLRVREL
What is the function of this protein?
Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).  In response to fungal infection and in associtation with AN2, is involved in the production dolabradiene, a type of antifungal phytoalexin (PubMed:29475898).  Converts ent-copalyl disphosphate (ent-CPP) to dolabradiene (PubMed:29475898).
What are the official names of this protein?
Dolabradiene synthase KSL4, chloroplastic, Ent-kaurene synthase-like 4, ZmKSL4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CD166_CANLF
Sequence: GSPVFIAFRSSTKKSVQYDDVPEYEDRLSLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKAPFLETEQLKKLGDCISKDSYPDGNITWYRNGKVLQPLEGVVVLIFKKQMDPVTQLYTMTSSLEYKATKADIQMQFTCSVTYYGPSGQKTVQSEQAIFDIYYPTEQVTIQVLPSKTAIKEGDIITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTKQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLQYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSTIINSPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREQVNHRATLIVGIVLRLLHGALVAGVVYWLYVKKSKTASKHVNKDLGNLEENKKLEQNNHRTEA
What is the function of this protein?
Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts.  Promotes T-cell activation and proliferation via its interactions with CD6 (By similarity).  Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (By similarity).  Mediates homotypic interactions with cells that express ALCAM.  Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction.  Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions.  Required for normal organization of the lymph vessel network.  Required for normal hematopoietic stem cell engraftment in the bone marrow.  Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow.  Promotes in vitro osteoblast proliferation and differentiation (By similarity).  Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM (By similarity).  Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
What are the official names of this protein?
CD166 antigen, Activated leukocyte cell adhesion molecule, SB-10 antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Note=Detected at the immunological synapse, i.e, at the contact zone between antigen- presenting dendritic cells and T-cells. Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse.
Protein: GATA_THIDA
Sequence: MPAPSLSALAAQLAAKQVSSRELAQQYLDRIAALNPTINAFITVDPEKTLAEAAAADALIAGGAAGPLTGVPIAHKDIFCTDGWLTTCGSKMLANFVAPYDAHVIERCKAAGMPSLGKTNMDEFAMGSSNETSFFGAVKNPWNAGYVPGGSSGGAAACVAARMAPAATGTDTGGSIRQPAALCGITGLKPTYGLVSRYGMIAFASSLDQAGPMAPSAEDCARLLNVITGFDPKDSTSLEREKEDYTRDLDLPLTGLRVGLPCEFFAEGLNNEVAAAVDAAVNELKKLGATTVEISLANSRLAIPVYYVLAPAEASSNLSRFDGVRYGYRAPEYADLNDMYAKTRAQGFGAEVKRRIMIGTYVLSHGYYDAYYLQAQKIRRLIAHDFAEAFKTCDVILGPTAPGTAFKLGEKSDDPVEMYLNDLYTIPANLAGLPGMSLPCGFDSQGLPIGLQLVGDYFSEAKMLNVAHQYQRVTDWHARQPEALA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PEX3_HUMAN
Sequence: MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIVNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK
What is the function of this protein?
Involved in peroxisome biosynthesis and integrity.  Assembles membrane vesicles before the matrix proteins are translocated.  As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
Protein: RL20_RICAH
Sequence: MTRAKSGKISKNRHKKILKLAKGYRGRANSCFRVAIEKVEKALQYAYRDRRNRKRDFRGLWIQRINAAVREHGFVYSQFIGALKKAEIDIDRKVLAELAVNNSDGFASIVEKTKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ARSC_HAEIN
Sequence: MSVIIYHNPHCSKSRETLALLENKGIQPIIELYLQKQYSVNELQSIAKKLGIDDVRQMMRTKDELYKSLNLDNLDLSQAELFKAISEHSALIERPIVINGDKAKIGRPPETVLEIL
What is the function of this protein?
Involved in resistance to arsenate.  Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.