PharMolix/UniProtQA huggingface dataset:
Protein: Y4725_BACC3
Sequence: MKVSYHGHSVVKIETNGKVILIDPFLTGNSKTDLKAEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVNTHPMHIGGSHEFDFGKVKFTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTVYHAGDTALFSDMKLIGELNNIDVAFLPIGDNFTMGPEDAVLAAKWVQAKTVVPIHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BCA_4725.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: Y1926_STRP8
Sequence: MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFTGDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDETTKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein spyM18_1926.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RIPS_PHYAM
Sequence: INTITFDAGNATINKYATFMESLRNEAKDPSLKCYGIPMLPNTNSTIKYLLVKLQGASLKTITLMLRRNNLYVMGYSDPYDNKCRYHIFNDIKGTEYSDVENTLCPSSNPRVAKPINYNGLYPTLEKKAGVTSRNEVQLGIQILSSDIGKISGQGSFTEKIEAKFLLVAIQMVSEAARFKYIENQVKTNFNRDFSPNDKVLDLEENWGKISTAIHNSKNGALPKPLELKNADGTKWIVLRVDEIKPDVGLLNYVNGTCQAT
What is the function of this protein?
Inhibits viral infection of plants, and protein synthesis in vitro.
What are the official names of this protein?
Antiviral protein S, PAP-S, Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: VA005_VACCW
Sequence: MYDDLIEQCHLSMERKSKLVDKALNKLESTIGQSRLSYLPPEIMRNII
What are the official names of this protein?
Uncharacterized protein VACWR005.
What is the protein family that this protein belongs to?
Belongs to the orthopoxviruses G3R protein family.
Protein: MUTS_LISIN
Sequence: MTEYTPMIKQYLEIKDKYQDAFLFFRLGDFYEMFFEDALNASQILEITLTGREGGTKEKIPMCGVPYHSASGYIDTLIEKGYKVAICEQVEDPKTTKGMVKREVVQLISPGTVMDERGLKAKENNYIASLYCYEGKEYGFAYSDLSTGELKSTVIEASEDRLINELTTLSTRELIVSESEKEVLSDVMKEQLGLTFSVHEEDTIPAENEKLVTRHMSLSEKRAIGKLLHYLKETQKRDLGHLQQAIHYETSNYMKMDYYSKRNLELAESIRGKGRQGTLLWLLDNTQTAMGGRMLKQWIDRPLIDRKQIIERQDDVSELMAHFFERLELVENLKNVYDLERLAGRVAYGNVNARDLIQLRNSLYQIPRIRATLLSMNSKSLTALANQLDPCEELTEKLEEAIVDSAPISIREGGIIKDGYNSQLDTYRDASRNGKTWIAELERKERELTGIKTMKVGFNRVFGYYIEVTRANTHLLPEGRYERKQTLANAERYITPELKEKEKLILDAEEKSMELEYQLFTEVREMVKDYIERLQKLAKSVSEIDCLQSFADISEKNHFIRPTLSEDGSLHVKQGRHPVVEKVMGAQSYVANDCDLDQNREILLITGPNMSGKSTYMRQVALTAICAQVGCFVPAEEATLPIFDQIFTRIGAADDLIAGQSTFMVEMLEARNAIVHATKDSLILFDEIGRGTATYDGMALAQAIIEYIHENVHAKTLFSTHYHELTDLEKELRGLQNIHVSAVEENGKVVFLHKIKEGPADKSYGIHVAELAELPKSLIERASRILEQLESNDKKIIITQDKQPEEIHEEVQLSMFPVEPEEKASSKETKLLKEIAAMNIMQMTPMDAMNKLYELQSKIH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HSLU_SHISS
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_HUMAN
Sequence: MSAHNRGTELDLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRKACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEWLKPELFRIGASTLLSDIERQIYHHVTGRYAAYHDLPMS
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.  Participates in stress granule (SG) assembly.  May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule. Nucleus. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.
Protein: HXD11_CHICK
Sequence: MTEFDDCSHGASNMYLPGCAYYVSPSDFSTKPSFLSQSSSCQMTFPYSSNLPHVQPVREVAFREYGLERGKWQYRGSYAPYYSAEEVMHRDFLQPANRRTEMLFKTDPVCGHHGASPAASNFYGSVGRNGILPQGFDQFYEPAPAPPYQQHSEGEGDADKGELKPQHSACSKAPSGQEKKVTTASGAASPPGEAVAEKSNSSAVPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D11, Homeobox protein Hox-4.6, Chox-4.6, Ghox-4.6, Homeobox protein Hox-4E, Chox-4E.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IGF1R_PIG
Sequence: ERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTEPVFFYVQAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNER
What is the function of this protein?
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1).  Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity.  The activated IGF1R is involved in cell growth and survival control.  IGF1R is crucial for tumor transformation and survival of malignant cell.  Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins.  Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways: the PI3K-AKT/PKB pathway and the Ras-MAPK pathway.  The result of activating the MAPK pathway is increased cellular proliferation, whereas activating the PI3K pathway inhibits apoptosis and stimulates protein synthesis.  Phosphorylated IRS1 can activate the 85 kDa regulatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB.  AKT phosphorylation, in turn, enhances protein synthesis through mTOR activation and triggers the antiapoptotic effects of IGFIR through phosphorylation and inactivation of BAD.  In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway.  In addition to these two main signaling pathways IGF1R signals also through the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT).  Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins.  In particular activation of STAT3, may be essential for the transforming activity of IGF1R.  The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity.  JNK kinases can also be activated by the IGF1R.  IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1, which is able to directly associate with the IGF1R (By similarity).  When present in a hybrid receptor with INSR, binds IGF1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NU301_CAEEL
Sequence: MAPPRGRSKRKHPSESGNSSIADSEDPSESTSSSRPRRSRLPKRYFDDGYSPPPTKKRAAQRETPSDAEEVEVKIEEISVRSTPASTPAPKSTSKARGRPKKNPTPPRRKSLKRQEEDIIYMDEDSEEEEESSDDEFMLNEDQVVQEEEEELNLTDIKIEKGLDEENKYCPWLDEDPASLPKLELPESSQDIPIPTASIMDAVEIYEILRSYHRTLRITPFTFEDFCAALISHNNSCIMAEVHMALLRNCLKSDDEEQTHYSVTETNNSVNIMIHHMDTLTYAEILRQYIEAYPFADASVRDAINVDNYPFVGYDAKLVVLLFMSYRFLYSSEFKKLVNNVGKFQNDENCRVCGKSSGRVVGCTQCEAAFHVECSHLKPFPEVLVCNICKKNSAVRGVLPPDEAVDREPLRSQPIGRDRYGRYYWFIVRRLVVQSLDETELYYYSTVPQLYQLLQKLDRTYYEKDLCDTIRLRIDEFLEQMALTVEMTSERREAALETMVKRQLIGYDFAEATTPQIYLHRDSMKRMASILRDCAQKGQVKQEVKLEEPVEGQSPVKCVQFVEDSILPESMIGIFDAKLINTFWSGGATQEELVEQFVDISDNFDAPSANLWRMGDEGNDQTFMTYYNYYSRNEMSESFLTRKKAADKKKYMASKFAQIDNFDWVVAKNRQFYGDASLHCKFIMWTLQQVIKNIPIDLMHRKWPEFAKGFDLEVSVADDYKKLVTCLLKLDCAVRKTIFMPQWWNGLGQTRLERITVDQRENFMKEQQRLKKIDADALTKDLDDSFVRVNYMKPKWPNTYILRQRGETYRNAGKGSMGGWAWVAAKYVEKWIQVPESPKLPLAVTVEEIKTESVSNRKARRLELLVSKITKKRQRSGGKSSKKPTFELTNGCYSPSCRSNPNRKCYSPMCRNGYLVSAKQAHDERKLEESGVLGEEKAWPIPEIQTFSTKRGGKSIFVLQKKILRQMIMGGGCQQVYMPGFSAGIKSNLLIWPYPAPRPTLDLCWKWQTLNARSLHAVALQLKIIWSSIKFNEFDPDDTHPDRRVVIDTPSHDERRRIIRHKEMPPYGQYERYEMEIEIIPLYDEPEEEDESWLSRNRGGSSEFSHRSSSARKKRPQRSLDNRRATAIRREWVDGVTLKVFEIKDYWKWIRAEAEKTAKRKLEATRKAQKAKEDEERRRIQQQQQRSVARIPVPMHSLIPSERNNVPYLGSQQQRRPNGNERGFLEKYNNSSSVSPQAHGYASTPPPGYHQPQPNIIRQAGYNQLPRKPTTSPFNFQSRPVATIPTTPQLRAAAGADGVVRAVMMTPGNKSTVNTNSTPYPQALNRQQYQLQRQQQQPAVRRLTNGYHFMDGTMRGGGRNPSVQMHQRLPQNRAALQRPFGESTTEMRRVTEAAIPDNDGDEQPPVIPRYDPTSNFDAQRAQQQHPQSRPVYSTPAQMIRTTQPGGVKHNVILMKASDGTQKMVLKPGQFPPGTVISTGQRVVPYRQPTAVQQRQLYTATPGTRVVRIPNANGGAPRQQDHQVMRRVVQASGPRAMEYMDDQGTPPPGQQVRYVLQGGNSGTPNVNPPKVSSRGGPRGGLTMQMVQQQQQHNPEHRRLLAGRQKQKVTTYRDFMASRGYLDTSKFMMQTKPTFLPFEFNEEEEREINEAIAREEAWMRQEEENKTSGYDSSGNPIRSITSSGDTQRAPPYVSNLLPSSNDSPDDKVIKQVLDVMFSQVCRWDRQYGWSKTHVKRARQKNDSDKMHLRKFRMNQRELLITDHMERLKKEINKRRTRMENEAEQQCGLLTPWRKARARPHRAAKPKAEVKKEVINPADITLGGDTYDYVKEQKPTESIATNVSRRRRTSANLSKSEDDRDKPESQSTAPKSKERRTSEPPASHVAFHTPGSATPHDINLSIEHCTCQKIFDASKLYIQCELCARWYHGDCVGVAEQTILGLEHWSCEECIEEQERVKDQPALYCVCQKPYDDTKFYVGCDSCQGWFHPECVGTTRAEAEQAADYNCPACTREAEGYESEASDVSGSSRVSVQLTRADYTHVFELLELLLEHRMSTPFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQMFENAKTYNPKGNAVFKCAETMQEVFDKKLIDVREQMTARQQMLLLATAQQQDPMSSIRKRVQSESQRTVDSLDIDSDQLLPLDANLMRLYDF
What is the function of this protein?
Histone-binding component of a NURF-like (nucleosome remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable).  Involved in vulval cell fates.
What are the official names of this protein?
Nucleosome-remodeling factor subunit NURF301-like.
What is the protein family that this protein belongs to?
Belongs to the BPTF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSTT_STRPM
Sequence: MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_LEPIC
Sequence: MSKGKIIVAMSGGVDSAVTAGLLMEDGYEVIGVNLRTWEYEAPACDTTKKSCCSPEDIRDARDVGISLKIPFYVIKMEKVFQEKVIDRFIEDYQHGKTPNPCVECNTFVKFGALFEKAKALGIDKIATGHYARIARNGERYAIANGIDVGKNQAYYLYGLSQENLKNVIFPLGEMTKPEVRQIARRMGLPVADKSESQEICFIPENDYRKFLEKKNVEFTPGFFKLKDGRIVGKHKGRENFTIGQRKGLGIAWKNPLYVISIEDDGSVILGEENETYNESFSVIDLNFQGLAPLNEGESLECRVQVRYRHIPIRCKITKMKEGLIVHPLEDVRGVTPGQSAVFYPLDSDYLLLGGIISKGSIQMRVAEPAISVLN
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMM1_POSPM
Sequence: MGNAYIFSLQPTFTQGLILGQFSILFLLVLVLKYLFFDTVSDHAYRTSSYQPKIERDEDEDGIALVAERLAPKPAQDGKQSGNECESADWLNALLIQVLEAYRVKLRDGLPGAEGDEVARKRVERFANQMRPPGFLDPIKVHSVDLGVTAPRLSRARPRPQKAPNTDPAIEFDMSYADTISLSLSTSVLFNYPFASFARLPVSLTISLSHFSSSVLLTPPQPHAQHPTVTLNLPSPGTDFVLNIQTKSLMGSRAKLADVPKLHEMITHQIQRVLLEKGTWKVVLPGLASVSEVKEDVKREQQAGELPVN
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: TRI13_HUMAN
Sequence: MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
What is the function of this protein?
Endoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD).  This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins.  Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation.  Regulates ER stress-induced autophagy, and may act as a tumor suppressor (PubMed:22178386).  Also plays a role in innate immune response by stimulating NF-kappa-B activity in the TLR2 signaling pathway.  Ubiquitinates TRAF6 via the 'Lys-29'-linked polyubiquitination chain resulting in NF-kappa-B activation (PubMed:28087809).  Participates as well in T-cell receptor-mediated NF-kappa-B activation (PubMed:25088585).  In the presence of TNF, modulates the IKK complex by regulating IKBKG/NEMO ubiquitination leading to the repression of NF-kappa-B (PubMed:25152375).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM13, B-cell chronic lymphocytic leukemia tumor suppressor Leu5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RING finger protein 77, RING-type E3 ubiquitin transferase TRIM13, Ret finger protein 2, Tripartite motif-containing protein 13.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: MIAA_LACDB
Sequence: MQKVVAIVGPTAVGKTSLAIEIAKKLDGEIVSGDSMQIYKEVAIGTAKASREEQAEVKHYLVDAHSVFEDFSVKNFVDEARSAIGEIAGKGKLPIIAGGTGFYVNALLNDMQLGDKEEEAASVDPEWEVFLAANGPQALWEELNKKDPEAAKKIPVANSRRSLRALSVISRTGGLFSKQQAEIKPRYDYLIIGLNSDREAIYQRINQRVDLMMEAGLLEEARFVYEHRAGEHQVLQAIGYKEFFPYFAGEASLETCVMALKTASRRYAKRQLTYFRNKLPVEWYDPLTDPNCANRIAVRIEEWMKEEK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GET1_PENRW
Sequence: MLSLVLTVFFVHVAIYLVNTIGASTIDSLLWLLYLKLPTPTSRTARKQQQLKRQVLEQKHEMNSTSSQDEFAKWAKARRRHDKSMEEYEALNKTLTAQKSSFDWTVKIARWLSTNGLKIFLQFWYSKTPVFPLPEAWFPYYVEWIVSFPRAPLGSVSIHVWSNVCATTIALTAEVMGALLVQIVGQKKEQRETAPVSAEGKKAQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIS8_ECOLC
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAMIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVTQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RNC_STAAE
Sequence: MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLH_ASPFU
Sequence: MTPKFDIDYVLANITEDDKIALLSGSDFWHTHAIPKFNVPPIRTTDGPNGIRGTKFFAGVPAACLPCGTALGATWDRDLLHQAGVLLGKECLAKGAHCWLGPTINMQRSPLGGRGFESFAEDPHLSGIMAKSIILGCESTGVISTVKHYVGNDQEHERRAVDVLVTPRALREIYLRPFQIVARDAHPGALMTSYNKINGKHVVENPAMLDIVRKDWHWDPLIMSDWLGTYTTIDSLNAGLDLEMPGPTRYRGKYIESAMQARLIKQSTISKRARKVLEFVERASRAPVSADETGRDFPEDRALNRTLCANSIVLLKNDGNLLPIPKTVKKIALIGSHVKTPAISGGGSASLEPYYAVSLYDAVVEALPDAEILYEAGAYAHRMLPVIDRMLSNAVIHFYNEPPEKERTLLATEPVVNTAFQLMDYNAPGLNRALFWATLIGEFTPDVSGLWDFGLTVFGTATLFIDDEMVIDNATRQTRGTAFFGKGTVQEVGQKQLTAGQTYKIRIEFGSANTSPMKAIGVVHFGGGAAHLGACLHMDPEQMVANAVRVAAEADYTIVCTGLNRDWESEGFDRPDMDLPPGIDALISSVLDVAADRTVIVNQSGTPVTMPWAHRARGIVQAWYGGNETGHGIADVLFGDVNPSGKLPLSWPADVRHNPTYLNNMSVGGRMLYGEDVYIGYRFYEKVGREVLFPFGHGLSYTTFHVSPEATVSPIVFSSDSPPTATVLVKNTGPMAGAQTLQLYIAAPNSATPRPVKELHGFTKVFLQSGEERSVSIHIDRYATSFWDEIEDMWKSEEGVYQVLIGTSSQEIVSRGEFRVEQTRYWRGV
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase H, Beta-D-glucoside glucohydrolase H, Cellobiase H, Gentiobiase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KPEA_ASPOR
Sequence: MSNVDISNDGFIGLDYDSRNYLQPQSWPVAVDHQASHRAEGARDISPLQTSGHAFEQSVAQDPNLMVDWQFQHMQPHLQYSHEEASSAPQFTTASYGMPIHSSPIDLISGTPQGPLSGSLLDGPYLPLSAPVDMVPFPYQDLQSDLMAFPSDGLAHGLPEIPSYAAPQNVIDSSSPADTYLEVRSLTSSSSDNGWSTIEPRRSHEYFPDQGFFINPTQTLHDRSLSESSYSTSYGSFVEISNPVNSPSSDTNFDAAFNNTMTRRVSFDHTSHGSQSPTAVSPVAIVRPIPVPMKKPSSPTRSTGSSSSTSPPTRKPSRKSPIAAKTAETKVRKQSQNGKPETEKRVGKRKGPLKPDQRKQASEIRKLRACLRCKFLKKTCDKGEPCAGCQPSHARLWQVPCTRIDIKEIGYFMKDWKADYERHISLGFSVGNIKGFSEHERTLFITHGYGQILPINAREVYVHNDQCFNVDWVETYNRGPTKYEVETAKLSAGMEGISHAMLSDYLDRHIDGNGTFEKFVDDYFEGTPFLTQMLKTAFRFYYRTKMPVIRKALKLIVAYNLTLHITLVEGLGEEDGLLGKVDVEGSKFKGKTLAPVMINFQIKCAMANMWRELQKDVLEELSSLYSSVYSGEKLKNWPTIFILASILLAVWEEMQFDCHYRTRDPAAVEKFCNDMETTPVGVIVGLFQAISQKLPAFTEWETQKHHHLLHSNPDVCSAMTEVRQHVTQYESYLRSRSSSKFNPKDFDCLSNKFVSRLVVRAN
What is the function of this protein?
Transcription factor that regulates conidiation as well as kojic acid production, likely by negatively controlling kojR and kojA expression.
What are the official names of this protein?
Transcription factor kpeA, Kojic acid production enhancement protein A.