PharMolix/UniProtQA huggingface dataset:
Protein: IMUA_CAUVC
Sequence: MEAGTRTPTPVLSFGEPSIDGCFPGGGLPLGGWHEVTGAGLEDETGAAPAAFVTQLIRGLTDRKGGAVVWVARRADLFAPGLLGLGFPAARLIQVRARDEAETLSLLEDALSTQGVAAAVAEAEAPDLTAGRRLQLACEKRGGFGVVLHRRPYGGRAGGKPRLVSGSASFSRWRIAPAPSGPPPDDIGLGPPRWRVELERCRGGRPGGWILQAQEAGHGPHPFRLVSQLADHDVAAAEAGRRFG
What is the function of this protein?
Along with DnaE2 and ImuB is required for the error-prone processing of DNA lesions.
What are the official names of this protein?
Protein ImuA.
Protein: RECO_PECAS
Sequence: MEGWQRAFVLHGRPYSETSLLLDLFSESDGRVRVLAKGARARRSSLKGCLQPFTPLLVRWSGRGEVKTLRSAEPVSLALPLTGSMLYSGLYVNELLARVLEHETNYSALFFDYLHCLQHLAAQDASPEPALRRFELALLGYLGYGVDFLHCAGSGEPVADTMTYQYREERGFTASLVVDNKSFTGHELHSLASREFPDVGTLKAAKRFTRIALKPYLGGKPLKSRELFRQFVPAANLSKPTSSDK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CHPE_PSEAE
Sequence: MLAIFLAALLFGFAFNVSPGAVFSETLRRGLTGGFRPALLVQLGSLIGDAVWALLGLTGLALLLGYEQVRIPLTLACAAYLAWLGVQGLRDAWSPPLAAEDAGEQGRNAFGAGAAISLSNPKNVVYWGALGSALAGIVDGTPNQAQSLVFFAGFMLSSLIWCFCCAALVDWLRRNTSLFWHRVSYAGCGVLLLGLAGLALRGL
What are the official names of this protein?
Chemotactic transduction protein ChpE.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1635_STAAS
Sequence: MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
What are the official names of this protein?
Uncharacterized peptidase SAS1635.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: SAE1_XENLA
Sequence: MVEKEEAVISEEEAAQYDRQIRLWGLEAQKRLRTSRVLLVGMRGLGAEVAKNLILAGVKALTLLDHEQVSSEDSRAQFLIPSGSLGQNRAEASLNRARNLNPMVSVEADTENINQKSDDFFTQFDVVCLTSCPSDLLVRVNHICHKHNIKFFTGDVYGYHGSMFADLGEHEFVEEKAKVTKAKPLVEDGPEAKKAKIDPTETILVKKKVQFCPLKDALEIDWRSEKAKSALKKTPTDYFLLQVLMKFRTDKGRDPQPSSYQEDSELLLQICSDVLDSLGVSPDLLPKDFASYCFSEMAPVCAVVGGVLGQEIVKALSLRDAPHNNFFFFDGKTSNGIVDCLGSK
What is the function of this protein?
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3.  It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 1, SUMO-activating enzyme E1 N subunit, Ubiquitin-like 1-activating enzyme E1A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSB_BURTA
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFSDDTIVVNVQGDEPLIDPQLVCDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDANGVALYFSRAPIPWSRDAYLPHWPNIAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVLVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LONP2_SPIOL
Sequence: MAEAVELPSRLGILAFRNKVLLPGAIIRIRCTSPSSVKLVEQELWQREEKGLIGIVPVRDASESASVAPVLYPGGGTDSGERNVKSQPGLSDSRKADGKSQQEAVHWHTRGVAARALHLSRGVEKPSGRVTYTVVLEGLCRFRVMELNSRGNYYTARISPLDITKADMEQAQQDPDFVSLARQFKVTAVELISVLEQKQKTGGRTKVLLETVPVHKLADIFVASFEISFEEQLCMLDSIDLKVRLSKATELVDRHLQSIRVAEKITQKVEGQLSKSQREFLLRQQMRAIKEELGDNDDDEDDVAVLERKMQSAGMPANIWKHAQRELRRLKKMQPQQPGYSSSRVYLELLADLPWQNATEEQKLDLRAAKERLDSDHYGLVKVKQRIIEYLAVRKLKPDARGPILCFVGPPGVGKTSLAASISAALGRKFIRISLGGVKDEADIRGHRRTYIGSMPGRLIDGIKRVGVSNPVMLLDEIDKTGSDVRGDPASALLEVLDPEQNKTFNDHYLNVPYDLSKVIFVATANKVQPIPPPLLDRMEVIELPGYTPEEKARIAMQYLIPRVMDQHGLSSEFLQISEDMVKLIIQRYTREAGVRNLERNLSALARAAAVKVAEQDNATAVSKDFHQFTSPVEESRLAEGAEVEMEVIPMGVDNREISNALQVMSPLIVDETMLENVLGPPRYDDRETAERVSNPGVSVGLVWTAFGGEVQFVEASVMAGKGELRLTGQLGDVIKESAQIALTWVRARAMELNLVATGEINLMEGRDIHIHFPAGAVPKDGPSAGVTLVTALVSLLSQKRMRADTAMTGEMTLRGLVLPVGGVKDKVLAAHRYGIKRVILPERNLKDLVEVPSAVLSNLEIIYAKRMEVLEQAFEGGCPWRQRARL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: PCKA_CAMLR
Sequence: MKGLENLGLENIGQVFHNLSYDELLKHEKNNNEGVCTKNGTFSVDTGIFTGRSPKDKYFVKQDPSQKYIAWGKINQAISEELFEKLLVKAKKQLSNSDIYIQDAYCGASLKSRKAVRFVTQIAWQAHFVKNMFIRPKEEELSGFKPDFVVYNACKCVNEDYEKDGLNSEVFVIFNIEKNIAVIGGTWYGGEMKKGIFSMMNYWLPLENKLPMHCSANVGEKGDVALFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDEGVFNFEGGCYAKCINLDPQSEPEIYGAIKQNALLENVVLKDDLSVDFNNGSKTENTRVSYPIEHILNHEPSLSAGHPSNIIFLSADAFGVLPPVSKLSKEQAMYYFLSGYTAKVAGTERGITEPVATFSACFGEVFLPLHPTVYAKLLGEKISKHNVNVYLVNTGWSGGAYGVGKRMSIKATRACINAILDGSIQNCEFENYDLFNLAVPKELAGVESKLLNPINTWEDKKAYEETKLKLAKMFIENFKRYEDVKEGAEFKLAGPAI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP1_RAT
Sequence: MGTLGKAREAPRKPCHGSRAGPKGRLEAKSTNSPLPAQPSLAQITQFRMMVSLGHLAKGASLDDLIDSCIQSFDADGNLCRSNQLLQVMLTMHRIIISSAELLQKLMNLYKDALEKNSPGICLKICYFVRYWITEFWIMFKMDASLTSTMEEFQDLVKANGEESHCHLIDTTQINSRDWSRKLTQRIKSNTSKKRKVSLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKENPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIHVAQKLHQLQNFNTLMAVIGGLCHSSISRLKETSSHVPHEINKVLGEMTELLSSCRNYDNYRRAYGECTHFKIPILGVHLKDLISLYEAMPDYLEDGKVNVQKLLALYNHINELVQLQDVAPPLDANKDLVHLLTLSLDLYYTEDEIYELSYAREPRNHRAPPLTPSKPPVVVDWASGVSPKPDPKTISKHVQRMVDSVFKNYDLDQDGYISQEEFEKIAASFPFSFCVMDKDREGLISRDEITAYFMRASSIYSKLGLGFPHNFQETTYLKPTFCDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFECKKRSKSPAVSTENISSVVPMSTLCPLGTKDLLHAPEEGSFIFQNGEVVDHSEESKDRTIMLLGVSSQKISVRLKRTVAHKTTQTESFPWVGGEMPPGHFVLTSPRKSAQGALYVHSPASPCPSPALVRKRAFVKWENKESLIKPKPELHLRLRTYQELEQEVNTLRADNDALKIQLKYAQKQIESLQLGKSNHVLAQMDHGDGT
What is the function of this protein?
Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP (PubMed:9789079, PubMed:9582122).  Activates the Erk/MAP kinase cascade.  Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras.  Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways (By similarity).  Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses.  May also function in differentiation of other cell types.  Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated (By similarity).
What are the official names of this protein?
RAS guanyl-releasing protein 1, Calcium and DAG-regulated guanine nucleotide exchange factor II, CalDAG-GEFII, Ras guanyl-releasing protein.
What is the protein family that this protein belongs to?
Belongs to the RASGRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Found both in the cytosol and associated with membranes. Relocalization to the cell membrane upon activation is F-actin-dependent (By similarity). Translocates to the Golgi in response to phorbol ester or nerve growth factor (By similarity). Localizes to somata and dendrites but not to axons of hippocampal pyramidal cells.
Protein: F6H13_IPOBA
Sequence: MPAVLSSVLSNITDFVVHEGNGVKGLADMGLQSLPKQYIQPAEERITTSTVIVDDTIPVIDLSEWGSDPKVGDLICEAAEKWGFFQIVNHGVPLEVLEEVKAATYRFFRLPAEEKNKHSKDNSPSNNVRYGTSFTPHAEKALEWKDFLSLFYVSDEEAAALWPSACRDEALTFMRNCDAVIKRLLKSLMKGLNVTEIDGTKESLLMGSKRINMNYYPKCPNPELTVGVGRHSDVSTLTILLQDQIGGLYVRKLDSDTWVHVPPINGAIVINVGDALQILSNGRYKSIEHRVIANGSNNRISVPIFVNPRPNDIIGPLPELLESGEKAVYKNVLYSDYVKHFFRKAHDGKETVDFAKIN
What is the function of this protein?
2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin biosynthesis (PubMed:22169019).  Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and, at low efficiency, caffeoyl-CoA into 6'-hydroxycaffeate, but has no activity with p-coumaroyl-CoA (PubMed:22169019).
What are the official names of this protein?
Feruloyl CoA ortho-hydroxylase F6H1-3, IbF6H1-3, 2-oxoglutarate-dependent dioxygenase F6H1-3, 2OGD F6H1-3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PGAP2_CAEEL
Sequence: MAFGDDDILSIPFKYFVICIGGLPSSALLICVILSLLLHFDQATSTHCEVANWLPSISAAVSTYTPEKYIWRILIGLHIGPRLVVAIAFRNFLLGSPLRPLTGHKRLRFLCNLACFLNLLENFFLLALTSISSSEDHSLHAKCFGGFAICSIIYMLLSTWLFNETGRRTATNLGQRSHEYKILGAAIFVLCFFLGAYLYWRHNTYCEPGIYTLFALVEYSAVLSNIFFHCTLYYDFHGKNIVLTSSFGGGHYNLLPTQIDKDT
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Required for stable expression of GPI-anchored proteins at the cell surface (By similarity).
What are the official names of this protein?
Post-GPI attachment to proteins factor 2.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ISCS_MANSM
Sequence: MKFPIYLDYAATCPADDRVAEKMMQYLTRDGIFGNPASRSHKFGWQAEEAVDIARNHIADLIGADSREIVFTSGATESDNLAIKGAAHFYQTKGKHIITCKTEHKAVLDTCRQLEREGFEVTYLAPKSDGLVDLDEFRAAIRPDTILASIMHVNNEIGVIQDIEAIGKICREHKVIFHVDATQSVGKLPINLAELPVDLMSMSGHKLYGPKGIGALYVRRKPRVRLEAIIHGGGHERGMRSGTLAVHQIVGMGEAYRICKEEMAEEMAHVTKLRDRLYNGLKDIEETYVNGSMEHRVGSNLNISFNFVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRYTTEEEIDYTIDLVKSAVKKLRDLSPLWDMFKEGIDMSKIEWSAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN12_LACBS
Sequence: MGIKGLTGLLSQHAPKAIKEIKTLFGRKVAIDASMSIYQFLIAVRQKDGELLTNDAGETTRYLMGLFYRTLRIVENGIKPAYIFDGKPPELKKGVLSKRLERREEAKEEGEEAKETGTVEDVDRFSRRTVKVTREHNQECQRLLRLMGIPVVIAPSEAEAQCAELARGGKVYIALYYAAGSEDMDTLTFNAPILFRHLTFSEAKKQPISEINLKEALEGPLYSFPTFIDLCILLGCDYLEPIKGVGPKSALKLIREYGGLKGVVKHLREKAATQKAAQAAVESDEESEHEEEDEPAPTSDVEMPDPVEEDQDGEEEAEPKSSQATPKKKKASSKTKEKRKGKGGGGMQIPEEWPWEEAKKIFKRPSHVHRDLEWTNPDVDGLVQFLVNEKGFNEDRVRKGAEKLQKFLNSKQQGRLDGFFSVKPKEKAAAPAPVGKAKGKGKIDAKAKGTKRKVDEKAESSAGKKPRKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-B, FEN-1-B, Flap structure-specific endonuclease 1-B.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: BIOC_ACET2
Sequence: MIDKKILQMHFSRNAKNYDAYAKVQKKMANTLLDMLDLDSKSRLDILDVGCGTGYLTKLLLDRWPDARITAIDIAPGMIEYARDRFNESNVEFACLDIEEAELNQKYDLVISNATFQWFNDLGGTVNKLVQSLKSDGVLAFSTFGHMTFSELHFSYETARRKLKIDEEFPPGQKFCNAKEILKICCETFEGLEGFEFDTVKKESLEYEYFYTVREFLDSVKKIGANNSNKQRKVNTALTKEMIRIYEEMFKVNGLVRATYHCIFITSRKKLAANTRRLVNAVV
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RL4_LISMO
Sequence: MPKLSLLKQDGTNAGEITLNDTVFGIEPNEKVVVDVILSQRASLRQGTHKVKNRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYAYKLPKKVRRLAIKSILSSKVNEEKLVVLEGLTFDAPKTKEFAAFLKNISVDTKALIVVAGESENVELSARNLQGITVIPAESISVLEVAKHDKLIITKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: VATB1_CAEBR
Sequence: MAAVDVNQTITGHKSAIIRNYTTNPRLIYQTVSGVNGPLVILNDVKFPQFSEIVKITLPDGSQRSGQVLEIAKNKAVVQVFEGTSGIDAKNTICEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPPVLAEDFLDINGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQIVRQGGLVQLPDRPHEQTNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRIALTAAEFLAYQCSKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRDGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIYPPINVLPSLSRLMKSAIGDKMTREDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEFLVKFEKNFISQGHYENRTIFESLDIGWELLRIFPREMLKRIPAKSLDKYYPRGGAKE
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Essential for the proper assembly and activity of V-ATPase (By similarity).  Required maternally for early embryogenesis and zygotically during morphogenesis.  Specifically, involved in the clearance of apoptotic cell corpses in embryos.  Also, during embryonic development, the V-ATPase is required to repress fusion of epidermal cells probably by negatively regulating eff-1-mediated cell fusion.  In neurons, required for necrotic cell death by promoting intracellular acidification.  Required for cell death induced by hypoxia.  Required for acidification of synaptic vesicles and the release of neurotransmitters from adult neurons (By similarity).
What are the official names of this protein?
Probable V-type proton ATPase subunit B 1, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RSGA_STAES
Sequence: MKTGRIVKLISGVYQVDVEGERFDTKPRGLFRKKKFSPVVGDIVDFEVQNTKEGYIHHVHDRNNELKRPPVSNIDELVIVMSAVEPEFSTQLLDRYLVIAHSYHLKPRILITKHDLASEQEILKIKDTIKIYQKIGYATQFIGKDSNYTATVDEWSDGLIVLSGQSGVGKSTFLNSYQPQLKLETNDISKSLNRGKHTTRHVELYDRKGGYIADTPGFSALDFNHIEKEQLKDFFIDIHEAGEQCKFRNCNHIKEPQCHVKALVEKGEIPQFRYDHYQQLYNEISNRKVRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_CAMJE
Sequence: MTLLDGKALSAKIKEELKEKNQFLKSKGIESCLAVILVGDNPASQTYVKSKAKACEECGIKSLVYHLNENITQNELLALINTLNHDDSVHGILVQLPLPDHICKDLILESIISSKDVDGFHPINVGYLNLGLESGFLPCTPLGVMKLLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVAAGCVNLLRSDMVKEGVIVVDVGINRLESGKIVGDVDFEEVSKKSSYITPVPGGVGPMTIAMLLENTVKSAKNRLN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: QUEF_BURTA
Sequence: MNPEHSPLGKTTVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARGKPQVAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESIDAVRDALKRDVSAACGASVTVRLATPAEFRKLQMDELDGLSLDRLDLDADVYETDPSFLTASHDEAPVEETLVTDLLKSNCPVTGQPDWGSVQIHYVGAPIDHAGLLRYIISFRNHTGFHEQCVERIFIDILRACKPVKLAVYARYTRRGGLDINPFRTNYNQPMPDNARTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_BAUCH
Sequence: MSSVSQARSLGKYFLLMDNILVVMGFYMVFPLISIRFVDQLGWTALLVGIALGLRQFIQQGLGIFGGAFADKLGAKPMIITGMLMRALGFIFMGIADKPWLLWVSCILSALGGTLFDPPRTALVMKLTRPWERGRFYSLLMIQDSTCAMVGALLGSWLLQYNFKLVCLAGALLFLFAAILNAWLLPAYRISNAQTSMLEGIRRVLYDQRFVTYVFTLTGYYILSVQVMLILPIRVNEVAGQLAAVRWTYAIEAALSLSLLYPIARWSEKRFSLENRFMAGLTIMLLSIIPIGMIHNLQVLFLLIGIFYTGSIIAEPARETLGASLADNRARGSYMGFSRLGLALGGAIGYSGGGWLYDMGNQLDIPQLPWVMLGMIGLITLLGFYRQFHQHHYQTYSXYLSGTTKNNSYKQ
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_SALTI
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RPOA_ALKCK
Sequence: MIEIEKPNIETVEVSEDAKYGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSVQIDGVLHEFSTIEGVVEDVTTIILNLKKLALKIYSDEEKTLEIDVQGEGNVTAGDLTHDSDVEVLNPDLHIATLTKGASFRMRLQAKRGRGYVLAEGNKNDDQPIGVLPIDSIYTPVARVNYQVENTRVGQVTNYDKLTLDVWTDGSTRPEEAVSLGVKILTEHLNIFVGLTDQAQNAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELTHKTEEDMMKVRNLGRKSLEEVQEKLGELGLGLRNEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PGH1_RABIT
Sequence: MSRSSPSLRLPVLLLLLLLLLLPPPPPVLPADPGAPAPVNPCCYFPCQHQGVCVRVALDRYQCDCTRTGYSGPNCTVPDLWTWLRSSLRPSPTFVHYLLTHVRWFWEFVNATFIRDTLMRLVLTVRSNLIPSPPTYNLDYDYISWEAFSNVSYYTRVLPSVPKDCPTPMGTKGKKQLPDAQVLAHRFLLRRTFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPPSVEEAPVLMHYPRGVPPRSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWDDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPEMLFSVQFQYRNRIAMEFNHLYHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQSAGRIGGGRNIDHHVLHVAVEVIKESREMRLQPFNEYRKRFGLKPYASFQELTGETEMAAELEELYGDIDALEFYPGLLLEKCQPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGSNLIKTATLKKLVCLNTKTCPYVSFRVPRSSGDDGPAAERRSTEL
What is the function of this protein?
Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response.  The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes.  This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins.  The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons.  Involved in the constitutive production of prostanoids in particular in the stomach and platelets.  In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection.  In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.  Can also use linoleate (LA, (9Z,12Z)-octadecadienoate, C18:2(n-6)) as substrate and produce hydroxyoctadecadienoates (HODEs) in a regio- and stereospecific manner, being (9R)-HODE ((9R)-hydroxy-(10E,12Z)-octadecadienoate) and (13S)-HODE ((13S)-hydroxy-(9Z,11E)-octadecadienoate) its major products.
What are the official names of this protein?
Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the prostaglandin G/H synthase family.
What are the subcellular locations of this protein?
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.