PharMolix/UniProtQA huggingface dataset:
Protein: OPGB_ECO7I
Sequence: MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLAAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSRTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKAIWKGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURD_STAAC
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KC1E_CHICK
Sequence: MELRVGNKYRLGRKIGSGSFGDIYLGANIATGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDMDRERREHEREERMGQLRGSATRALPPGPPAGATGNRLRNVAEPMASTPTSRIQQSGNTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRISASQTSVPFDHLGK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  Can phosphorylate a large number of proteins.  Participates in Wnt signaling.  Phosphorylates DVL1.  Central component of the circadian clock.  May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2.  Retains PER1 in the cytoplasm (By similarity).
What are the official names of this protein?
Casein kinase I isoform epsilon, CKI-epsilon, CKIe.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARF5_RAT
Sequence: MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor.
Protein: PLS5_PHAJA
Sequence: FLSLIPHAISAISAIAHHL
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Phylloseptin-J5, PLS-J5, PS-J5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIP12_CRIRI
Sequence: FLPPCAYKGTC
What is the function of this protein?
Induces mouse splenocyte proliferation through binding to CCK-BR.
What are the official names of this protein?
Riparin-1.2.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_LEGPC
Sequence: MRPSNREHDQLRPVTITRNFTNYAEGSVLVEFGQTKVICNASIVEGVPRFLKGKNQGWITAEYGMLPRATHSRTEREASKGKQGGRTLEIQRLIGRSLRACIDLKVLGENTITLDCDVIQADGGTRTAAITGSCVAMRDAIHWMVQREKIKKMPVFNYVAAVSVGIYRGQPVLDLDYAEDVLAETDMNVVMNEQGHFIEVQGTAEDNSFNREQLNSMLSLAEIGIPQLIEIQKNA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: HUTI_KOSOT
Sequence: MRVDLTITNLSEIVSPKGKPPVCGKNMSQLSIRKNKNIAIKDGKIVYIGSEIPPALRTINANGAIALPGLVDPHTHIPFTGNRAHEFIMRLHGKSYMEIMQAGGGILSTVKAVRKASLKELVLRGAYALNEMLKLGVTTVEGKSGYGLEKTAEIKQLKALKLLNKVQLVDVIPTFLGAHALPEEFEDKKEYLNYLSNMLKDVREYTDTVDIFCEKGVFEVEESREFLERAKAMGFRLRLHADELAPSGAGKLAVELGAVSADHLISADDETLEAISKSATTAVILPGTSFFLKERFARGRKMIDLGSAVALASDFNPGSCNIYDPYLIMHLAVTRCGLEIEEAVTAYTINAAHILNLSNRKGKIEEGYDADIVLLGLNSYTEIPYMFSRITVVSVIKSGRVVFHES
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP1_NOCFA
Sequence: MSTYTIPNVIAQHPRGGERITDIYSHLLAERIVYLGTPIDSGVANALIAQLLHLESESPDQEINFYINCEGGDLPSMLAVYDTMQHIGAPVHTTCVGQAIAVGAVLLAGGAPGQRAMLPHARVVLHQPAARGQGPIPDLILQADELVRMRSEIEAILSRHTGRSPEQLREDTDRDRVFTATAALEYGLIDTVLSPRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCTN_PSESY
Sequence: MNAALNLWKDAHAKRLSQYCAVRVIGRVSAVRRILLECRIPSAKVGDLCEVSKADGSLLLAEIVGFTQECTLLSALGPPDGIQVGAPIRPLGVAHRIGVDDSLLGCVLDGFGRPLMGDCLGAFAGPEDRRTTLPVIADALPPTQRPRITRALPTGIRAIDSAILLGEGQRVGLFAGAGCGKTTLMAELARNMDCDVIVFGLIGERGRELREFLDHELDETLRRRSVLVCATSDRSSMERARAAFTATAIAEAFRARGQKVLLLLDSLTRFARAQREIGIASGEPLGRGGLPPSVYTLLPRLVERAGMSENGSITALYTVLIEQDSMNDPVADEVRSLLDGHIVLSRKLAERGHYPAIDVSASISRILSNVTGRKHQRANNRLRQLLAAYKQVEMLLRLGEYQAGADPVTDCAVQLNEAINAFLRQDLREPVPLQETLDRLLQLTSQLPE
What is the function of this protein?
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (By similarity).  Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity).  Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (By similarity).  May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (By similarity).
What are the official names of this protein?
Type 3 secretion system ATPase, T3SS ATPase.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUPE_DICDI
Sequence: MINIEDISKSSNQSEEKQLKSTSSKPKYSFAAKSLFKGSNNITPYYLSTSNTFQCVASESIQTWLLSDDGHIFTSSGNFVLDVSSGGYFVELVQLNSNSKTQIWTIDTTNNKIQNQGNGKYLDIDNLNIYVAPLNGNATQQWTTFRRAPIPTGNWGYFQSKQLDSNNNYWGLSVLNNSTSYNTSVVMNKVQAKSIKRWSHFITFGGNLVLDIGPSINGSKTYYLNTNVYKANDLMQQWGINENNQIFNQYYPNLCIGFVGELGVDSTVNCVLAQPSSACDINFQWIANPTYSLNQIVSEVPEQFPAYTSGDLLASYQYLSDDATNGYTDDIRSLYTSINVSLENFYVNVTNATCPSSIHQLKIFQNQIKNELTYAINVRLVFDNYSGFYSKLFSQGSTNLTNLANLINVDMSSDQVVNGNYTDAITSVFYAIISEIPIGGSIIANIGESAEEFGELDAESNDSGPSTYQVTLSKLYDHLNENYENEMANAQRMKNTILQDWGMMSKTFTLCFLPTNNPSSLNMNGFDFQKISSIASLAYLTAMIQMLLPTNYQIYFTPAGYYAPVSSDDYSYTDSTGTYIMAEIDNCNSHPPKALTDKLWKNGVSKQEVFTSSYGWNLATSVTYYNMVGKYGGMFKLSFPTVKNITSVPMQFVMTNGSDRVGTFNVKTHFAGLASTYYNSGALGHHYYDIAVTDIDRNKVANFTVDNNLEALEGSYVSIKTNSLVVQPGYVVGNPTCNQGSFSQGFAASILIPIYKSN
What is the function of this protein?
May play an important role in stabilizing and/or regulating the cell membrane during Ca(2+) stress or certain stages of development.
What are the official names of this protein?
Calcium up-regulated protein E.
What is the protein family that this protein belongs to?
Belongs to the cup family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: FPG_SHEON
Sequence: MPELPEVEVTRQGITPYLVDQTVVDLIVRNPSLRWPVPELAKQIIGQTIRQVRRRAKYLLIDTDAGTSIVHLGMSGSLRILPHDTPVEKHDHIDLVLANGRILRFNDPRRFGAWLWCQLPEEAHPLLEKLGPEPLTDAFNVNQLAASLAGKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPEAEAGKIDIERLTVLVAEVKQILAHAIKQGGTTLKDFTNADGKPGYFAQKLHVYGRGGETCTQCGNLLSEIRLGQRTTVFCSICQPR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DMS3_PHAJA
Sequence: ALWKNMLSGIGKLAGQAALGAVKTLV
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-J3, DRS-J3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COAX_THEP3
Sequence: MLLVFDVGNTNIVMGIYKGKKLLHSFRISTEKSKTSDEYGMLINQLFEYNGLKLKDVDAVIISSVVPPIMHTLESMTIKYCNTKPLIVGPGIKTGINIKYDNPKEVGADRIVNAVAAYEIYGGPVIVIDFGTATTFCAISKNCEYLGGIIAPGLAISADALFQRTAKLPKIELTKPSTVICKNTVSSMQSGIIYGHVGMVDYIVSRMKEEFAPNAYVVATGGFARMIAEESKTINTVNDMLTLEGLRIIYERNAD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_TOBAC
Sequence: MVREKVTVSTRTLQWKCVESRTDSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRVKSEKVPHEYSTITGIQESVHEILMNLKEIILRSNLYGTSDASICVKGPGSVTAQDIILPPYVEIVDNTQHIASLTEPIDFCIGLQIERNRGYLIKTPHNFQDGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHMEEDNLYLQDNQHTVPLSPFTFHDKLAKLIKNKKKIALKSIFIDQSELPSRIYNCLKMSNIYTLLDLLNNSQEDLMKIEHFRSEDVKRILGILEKYFVIDLAKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EX7S_CLOK5
Sequence: MPRKTETYKSIMLKLENIVASMDSSELSLENSLKSYEEGVKLCNKLYKILNEAEEKIKVLTEEGERDFDIES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_TROW8
Sequence: MRYSKIVSLGAYRGERDVYNDELIGPINSSDEWIRRRTGIISRKRALSGTTVVDMAYAASKEALNDAQMRPEDIDLILVATITHFGHTPSVAAHVGFRIGVQDAILLDINAACAGFSYAIFQADLMIKSGVASRALVIGVDKLSEFIDPLDRTISFLLADGAGAAILVGSTSMGIGKTVCGGNPGQLESVGLTGSTTDVKSGSAWPTLRQEGSSIFRWAVWQMAKVAKQILDINQVQPGDLNAFIPHQANIRIIDELAKQIGLEENVLIAQDICKTGNTSSASIPLAMHSLIKGNPSLSGELALQIGFGAGLVYAGQTVVMP
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQL_HAEIN
Sequence: MKKTTALFLLIFSLIACQSLELSPNNNLPFDPNIQHGKLSNGLQYFVLKNTEPKERVYIRLVINAGSMHEDDDQKGIAHLVEHMAFNGSKKYPENQIINALEKLGMKFARDINAFTDFENTVYTLNLDSNNQQKLELAFDVINEWMNNITFLPKDVDGERGVVQEEWRRRLSPMLRIGNKKSAIEMAGSRYVLRDPIGDMDIIKTISAKRVADFYHKWYRPDNMSVIIVGDIDTKQVVKLLKQNLSQENPITKTTLEKIDFNIPLINKWRLDSISEQGTTIPSIELSFFENTIETNTLASYKQELIQQITTRLLNLRLQQWEKETENGVDSANFYRTHLGKETLQSIFSLQLIDTQYSKTIDKLFAFIASIKQQGFTQNELSGEIKRLTQLNEKQLNIRSGSLKIADDLITSVANKQVVLSVNDRYELNKRFLSQITLADLQRTLNQTLALKAKLLLITQPLPQKALPFDVAEIETRWNNVMEMQQHQWDEKKQIEKLPHLTFNTGSLSQEKYWDRGDIYEFRLSNGSKLIYHYSDKTPNQVHFRAVTQGGLRSIPNKDYHLLRAAVSVVDETGVGELSLSAVNQIFSRDPLVIATVIDDDKQGFTGVSKPKDLENLLTLFRLKLRSSPISDLALEKYRRETRDYFKQIDLETQFMQAVSKLRFPNIETVYTQKQAQQLSFDKNQLNNAYQHYILDKTDFTYFIIGDIELNQVKKLAERYLASIESKTQIRHFVPTIIHTPTQSFIMNGLKEPRADVEIYLTADNTWRTEQKYLFNILADIVQEKLRLILREKVSGIYSVNSWFMQDVYAPQIEGKIEFSCDPKRVEELTYLTNQVLDDIIKNGIDENLLRKKLAEQHTQIRREFDSLVSIASIIEESYWQQDNPDAIYTYQHLDQLATKATIDALAQKALKKSGRFVSILKAASY
What are the official names of this protein?
Probable zinc protease PqqL.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: RL29_NEIMA
Sequence: MKANELKDKSVEQLNADLLDLLKAQFGLRMQNATGQLGKPSELKRVRRDIARIKTVLTEKGAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HLP_RICFE
Sequence: MTITKEKIATMLSSKLGFSNNLCEEIVNTVFFNILEIAKEQKLTLKNFGSFEVKQKNPRPGINFHTKSPIIIESKKNLRFIPSTKLKALINEHDK
What are the official names of this protein?
Histone-like DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: HISZ_STAES
Sequence: MNNTIISMKEKELRFLKFFHQQKYNVVDFNLIEELDWRRLTHEDLQQMDERSFWQQNKSIYALRNDFTDQLFRYYSNYPTHLKKVAYAGDIIRDNRVIKQVGIENYEPQFDNITQNFLDFQYFIQNVLHDDIQFVILGHYQLIDALLEKNHQTREVMEMIEERNLSGLIQKLTFNHPIIQILKENTLNQLKILSHYLPERHPAMVAIQSWAQWFTDHGITEIHLDVTAQAPRSYYKGIFIKCHLKNTTHSVLTGGYYHGSLEGFGLGLTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAE1B_METM7
Sequence: MDTSKDLICIGFEGTAEKTGVGIITSKGEVLFNKTIIYTPPVQGIHPREAADHHAETFVKLLKEALTVVPIEKIDLVSFSLGPGLGPSLRVTATTARALSLSINKPIIGVNHCISHVEIGKLKTDAVDPLTLYVSGGNTQVLAYTGKKYRVIGETLDIAIGNCLDQFARHCNMPHPGGVYVEKYAKDGNKFMKLPYTVKGMDISLSGLLTAAMKKYDSKERIEDVCYSLQETSFSMLTEITERALAHTNKAEVMLVGGVAANNRLKEMLDVMCSEQNVDFYVPEREFCGDNGAMIAWLGILQYLNGKRMDLADTKPISNYRSDMVEVNWIHEENNNSENGNIKSRIIPEHLIGKGAEADISKGRYLEFESITKERVKKGYRTSELDELIRMRRTVKEARFLAAIKELGIYAPSIFDIDKENKKIAMSYIHGKIAKEKIEEGSIDFCEDLGKIIGKMHVGGIVHNDLTTSNFIVSDNTFVIDFGLGKYSDLVEDKAIDLIVLKKSIMSIHYDKFDRVWNKIVEGYKTYNLAESVLECMKEVEKRARYL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  The Kae1 domain likely plays a direct catalytic role in this reaction.  The Bud32 domain probably displays kinase activity that regulates Kae1 function.
What are the official names of this protein?
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_BACC3
Sequence: MTTTTTVKSDIEIAQEASMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQNEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDNHIQQGNTLGIDTRKIVWKRCVDLNDRALRNVVIGLGGPVQGVPREDGFDITVASEIMAVFCLATDIQDLKARLSRIVVAYNFANQPVTVKDLGVEGALTLLLKDALKPNLVQTLENTPAIIHGGPFANIAHGCNSVIATTMAAKLGDYVITEAGFGADLGAEKFLDIKARAAGIKPEAVVIVATIRALKMHGGVAKDQLKEENVDALAKGMENLQKHVETIQSFGVPFVIAINKFITDTDAEVAYLQEWCNERGYAVSLTEVWEKGGQGGVDLAEKVLKEIEKGENNYAPLYELELPLEEKIRTIAQKVYGAKDIEFAPKARKQLAQYEGEGWSNLPICMAKTQYSLSDDATKLGRPSDFIVTIRELKPSIGAGFIVALTGTMLTMPGLPKQPAALQMDVNEDGKAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RL6_PARP8
Sequence: MSRVGKSPIALQGAEVALSDERITVKGPLGSISQNANRLVKVVNDNGTLKFEPADESREANAMSGTMRALVANMVHGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGVKAETPSQTEIVIKGIDKQKVGQVAAEVRGYRPPEPYKGKGVRYANEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NELFD_MOUSE
Sequence: MAGPAPGTIMGEDYFGNASEWGEEADGGQHQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRVAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSRGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVETWKKNKRVSIGKDELKSTSKAIETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNFIVVN
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity).  The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity).
What are the official names of this protein?
Negative elongation factor D, NELF-D, TH1-like protein.
What is the protein family that this protein belongs to?
Belongs to the NELF-D family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAA_BRUC2
Sequence: MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRLIHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRPRADLILRKGSDHLIEEVALRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_CORGL
Sequence: MSDDRKAIKRALISVYDKTGLEDLAQALHRENVEIVSTGSTAAKIAELGIPVTPVEELTGFPECLEGRVKTLHPKVHAGILADTRKEDHLRQLKELEVAPFQLVVVNLYPFAETVASGADFDACVEQIDIGGPSMVRAAAKNHPSVAVVVSPNRYEDVQEALKTGGFSRAERTKLAAEAFRHTATYDVTVATWMSEQLAAEDSETEFPGWIGTTNTLSRSLRYGENPHQSAALYVGNTRGLAQAKQFHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDESIAAAHREAHACDSVSAFGGVIASNREVSVEMANQVAEIFTEVIIAPSYEEGAVEILSQKKNIRILQAEAPVRKGFESREISGGLLVQERDLIHAEGDNSANWTLAAGSAVSPEVLKDLEFAWTAVRSVKSNAILLAKNGATVGVGMGQVNRVDSARLAVDRAGAERATGSVAASDAFFPFADGFEVLAEAGITAVVQPGGSIRDNEVIEAANKAGVTMYLTGARHFAH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RBL_EUGPI
Sequence: YRLTYYTPDYQVSDTDILAAFRMTPQPGVPAEECGAAVAAESSTGTWTTVWTDGLTQLDRYKGRCYDLEPVPGESNQYIAYVAYPIDLFEEGSVTNLLTSIVGNVFGFKALRALRLEDLRIPPAYIKTFWGPPHGIQVERDRLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQSFMRWRDRFXXXSEAIYKAQSETGEVKGHYLNATAGNVEEMYKRAAFAAQLGVPIVMHDYLTGGFTANTSLSMYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKTLRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDPYVEKDRSRGIYFTQDWCGMGGTMPVASGGIHVWHMPALTEIFGDDACLQFGGGTLGHPWGNAPGAAANRVASEACVQARNEGRDLSREGGDVIREACKWSPE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.