PharMolix/UniProtQA huggingface dataset:
Protein: PXPA_ECO24
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSTFAEKEIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y344_HELAH
Sequence: MGRAFEYRRAAKEKRWDKMSKVFPKLAKAITLAAKDGGGDPDTNAKLRTAILNAKAQNMPKDNIDAAIKRASSKEGNLSETTYEGKANFGVLIIMECMTDNPTRTVANLKSYFNKTQGASIVPNGSLEFMFNRKSVFECLKNEVENLKLSLEDLEFALIDYGLEELEEVGDKIIIRGDYNSFKLLNEGFESLKLPILKASLQRIATTPIELNDEQMELTEKLLDKIEDDDDVVALYTNIE
What are the official names of this protein?
Probable transcriptional regulatory protein Hac_0344.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHB1_STAAB
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKISPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CE162_COTCO
Sequence: MLEKFHKNKKDSYLNKEEGSLTSDGSDSPKEILETSERIVKKALQLTEETDENVHPEKMQLQKSNGVAFSLSRDSLETNDSFVASGPNQSNTGLGLDTLEEQEEKEIFFAKLEQEASSPIDYSRLNKELNLSDSIVLAPFVRNESEKEVESTAEEKCESYSEDFEEDTDANPAFKTEESQEPNSGMLAKVVLLDSQDSTTEFQKAAETSGVALSEHDLPQEVGGTEMNEAGTLCGQTTSDTEALHHAYHHHIDQSLGDTDEQKIHSSSMAISQCLVQVTSQNHNLYSKNTSTTESDLPTVEEFMRPIKGDCYNARGFDLEPESPVKVIGSTVNEHVNHLPYKEHKNESVWETNLLEKFNREDSIFLQTAANEDSFLRMPGKEIQTSEVQPDVLSKEIIQDCLLSQGSKTKQVLQSCCLKNEKSESTTTKQMLYKNIRSTTPLHKKKSSYGPHGVVRSSGYGKSTSYSKQSIPATERKIPKETLKKSIMKCRSPADKARSKEALFTTRTIRSAANQQASKEDISRAMPDQSVVQNLGHQVVDSFRQHHSDLPVSPVKSCERELRLLRRAQVAEEDLSRARDVIQQLTSTVSEKEKEMETKIVELKTRYEKELSQLGQENYVLQSKLRSVEELSKEKRWIHQTGTVSVPEEKLAQIQKEMEDQEVIIQGYQQENERLYKQMKDLQIQNKKNEEQMYKENQCLMSELIALREKVERINIQSQIVRESEPARNQSFTELISELRAARKEETKLREEIRRLKQDKQALELDLGQAKKERDLAKVQITSTSSEKSYEFKIMEETYKQEILHLKRRLHWYAENQDLLDKDAARLKEAREEIEKLKQEVKKLRAEAGDHQCVQQKKRLRDRAADAKRIQDLERQIKEMEGILKRRYPNSLPALIYAAAAAEKTNDLSAKTNTTDFLERRIKKLETELEGKDDEAKTSLRAMEQQFQKIKMQYEQRLAELEQLLAYKWKSESPKLNGDKANCIELELQLQNLKKTHQITVENLQTEIENLKSQNSQLKLRSKKDNKDLQLADWQMKQGNTKEKLLKLNQELITKNREIQDLTKTVEKLQKERMAMLSDNNLRNKTDNKENRQESLKNNTVATEKRNSCNSEPLIGIFNNDKIYQPHNFSDSNVLEVLQENARLKEEVEKLSLEMNQQRVKSQATLAYSENNIRRIQEDTAEYVAALKASHQREVEKILSQYTKDDSASKVAELNGRISTQEILIKHLQEQISEHQRHQEALLVSQMREEF
What is the function of this protein?
Required to promote assembly of the transition zone in primary cilia.  Acts by specifically recognizing and binding the axonemal microtubule (By similarity).  Plays a role in cell proliferation and differentiation in the neuroretina.  Has an ATPase activity in vitro.
What are the official names of this protein?
Centrosomal protein of 162 kDa, Cep162, Protein quail neuroretina 1.
What is the protein family that this protein belongs to?
Belongs to the CEP162 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Note=Localizes to the distal end of centrioles throughout the cell cycle.
Protein: MNHA1_STAAB
Sequence: MSLLHIAVILPLIFVLIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLNKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFNIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit A1, Mnh complex subunit A1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CB076_DANRE
Sequence: MMCDRAVLTVRLVRSFEHRNFKPLVFKDVNLDQTVDEFISFVKQDISVRAGLPPPFRKFDYDTLKIIHQAHGAKTNELVMSLEDDEKLILREGCRLRACGVANETELAFFKMTDYIKFKADPHSEW
What are the official names of this protein?
UPF0538 protein C2orf76 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0538 family.
Protein: MRAY_AZOC5
Sequence: MLQWLAQLHDTFPAFNVFRYITFRTGGAIVTAVLFVFLFGPGIISTLRLKQGKGQPIRADGPQSHLLTKKGTPTMGGLMIFSGLIVATLLWANLSNLYVWVVLFVTTGFGLIGFYDDYLKVTRQSHAGFSGKARLAIEALIAGIAVVLMINAGRAGLSSSVAFPFFKDLLLDLGWFFVVFGAFVIVAAGNAVNLTDGLDGLAIVPVMIAAASFGMISYLSGNVVFADYLQIHYVAGVGELAVICGAIIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGSIAVATKHEIVLAVIGGLFVLEAVSVIVQVISFRLTGKRVFRMAPIHHHFEQLGWTESQVVIRFWIIAVVLALLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRG5_XENLA
Sequence: ILYEQPSYRGHQYYLWKGEYPDFQRWMGFNDSIRSCRMSPYHQGQYKMRIYERGDFQGQNMEFFEDCPNTYDRFRFRDIHSCNVFDGNWMFYEEPNYRGRQYYLRPGEYRRYSDWGASSARIGSFRRVHHLV
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin-5, Gamma-5-CRY, Gamma-crystallin V.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RBFA_BRUMB
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRFPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_SALTY
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLSVDANAHCDNPMADLQLVSDDLGDLQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHIITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSB5_SCHPO
Sequence: MGIFSETVPITAVTTYIDRLTSRDTDDEDLSGIVQLSEAVNLTVTGPREASRTLRKKLKYSTPHEQVRALVILQALIENAGSHFLQNFSDEKLEDRMLQCATNSEYSKPVRKRAIHMIKLWHNDYSNVRGMESMSSLVSRLPQRQSSASHSEQPTINLKKVGPILERLIASSSMAATNLSNSLVRINPNTENPAKNKQIMVYYVDCKRAHRSLLRYIQAIQDEMWLANLLKANDEIVTAIDAFKEKCSENSDYSSDSGSYSSSYSRHLDDRASYISRSSSGGSNAQRSEDLDVNNPFGDHNRLE
What is the function of this protein?
Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking.
What are the official names of this protein?
Protein lsb5.
What is the protein family that this protein belongs to?
Belongs to the LSB5 family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Protein: MSHR_LEOCY
Sequence: MPMQGAQRKLLGSLNSTPTATSNLGLAANRTGAPCLELPIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSSMYCFICCLALSDLLVSGSNMLEAGVLATRASVVQQLHNTIDVLTCSSMLCSLCFLGAIAVDRYISIFYALRYHSIMTLPRAQRAVAAIWVASVLSSTLFITYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLAWACQHAQGIIRLHKRQPPAHKGFGLRGAATLTILLGIFFLCWGPFFLRLTLVVFCPQHLTCNCIFKNFKVFLTLIICNTIIDPLIYAFRSQELRRTLKEVLGRGRW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF2_XANC5
Sequence: MSQQTTIRKLAELVNTPVDKLLVQLAEAGMKFSGPDQVVTSTEKMKLLGFLRRTHGKAETSAEAASEAAKKITLNRRKLQEVTVNAGRTKTTVNVEVRQKRTYVKSENEGSGRAAPMTPDEERADILRKLEESRQRNLEEQQRLAESDRVRDEAIQRKREEEQAAKDRAEAERKAAEEAAAAASAPAPVADAPTPSAAAPAARSPSSPSSAPRAARPAGASPASRPAAPARADDRSNAAKHKTRGSHVMVAGVEDDDATKRFAGQLHLSAADRARRSNVRGKPTGRPGSSSSRRGNDNGRGGSQANSGPHGFERPTAPVVREVAIGETITVADLAQKLALKGGDVVKALFKMGVMATITQSIDHDTAALVTEELGHKAVRADNADFEDALLAHAEDAQGEATSRPPVVTIMGHVDHGKTSLLDYIRRTKIASGEAGGITQHIGAYHVETGRGVISFLDTPGHAAFTSMRARGAKITDIVVLVVAADDGVMPQTKEAVAHAKAAGVPLIVAVNKIDKTGADPLRVKNELLAENVVAEEFGGDTQFIEVSAKVGTGVDTLLDAISLQAEVLELKAVAEGRASGTVIESSLDKGRGPVATVLVQQGALKRGDYLVCGIQYGRVRALFDETGHQPASAGPSIPVQVLGLSGVPEAGDDFVVVDDERLAKDVAQQRETKRRESRLVASATNRMEDILAQMGKGEGQQVLNLVIKADVQGSVEALKQSLVALSNEDIRINVIHSGVGGITESDANSAAASKATIIGFNVRADASARKIVESNGIDLRYFSIIYDVIDQVKQVASGLLGVEIREEIIGIAQVRDVFRSSKFGAVAGCMVIEGVVKRSKPIRVLRDSVVVFEGELESLRRFKENVDEVRNGTECGIGVKAYNDVKAGDQIECFERIEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAT1_USTMA
Sequence: MKSNVDTVLDGYTSVPVGVLDSTLANTDILTRITLVFPSSLSLSALQESWYALVRSWPILAARVRATPSTPSGLSYLIPTPATLESLETRSRNSASKPLEKHIVLLDQSSRSFSDYHPIVAKAVHSNLDRNNISIGGAPLVEHEKATICSNACTSWKQLIKQDQAFVTAQATKFADATTVTISFSHILGDAFTIKHIFQGWQTALNGQAVQELQDVGKDPFIKYLPKDTNDKKHKKNKKSEPAPDLPLQWFRYGLARKIKLISLLLWEVKVKKPEKTLGQYYIYLPQAKVDELMAQARSDLEQLRSSSATSATERDLNVSTFNVLFAWLLQNIHASTAIKPSKTSSVICIINAKTRPPAGHVPADYPRHQLWGGALGAPLRPLSAAEYVTLPLGQLALHIRESITEQVDPENIRKSVVMALKHSMWKKPSGELLFFSQNPNTYWCGCTEWRSAKFHTIDFSAAATPHHDAIQPTAAPAASVNPVAITTNMETPMTKRNRWALLGEANNGIWFTGGLTANEASNKNGFGRYIFVE
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (PubMed:15932999, PubMed:16885300).  Mannosylerythritol lipid production is responsible for hemolytic activity of Ustilago maydis (PubMed:15932999).  Depending on the number of acetyl groups, mannosylerythritol lipids can be differentiated into MEL A (fully acetylated), MEL B and MEL C (monoacetylated at R-6 and R-4, respectively), and the fully deacetylated MEL D (PubMed:31103599).  The first step in the pathway is the generation of mannosylerythritol by the glycosyltransferase EMT1 which catalyzes the transfer of GDP-mannose to the C-4 atom of meso-erythritol (PubMed:15932999).  This reaction has to be stereospecific, since only mannosyl-D-erythritol is generated (PubMed:15932999).  The produced disaccharide is subsequently acylated with fatty acids of various lengths derived from the peroxisomal beta-oxidation by the peroxisomal acyltransferases MAC1 and MAC2 at positions C-2 and C-3, repectively (PubMed:16885300, PubMed:24835306, PubMed:31103599).  The existence of MEL derivatives which carry an acetyl group at C-2 implies that at least MAC1 also accepts acetyl-CoA as a donor (PubMed:15932999).  The final step of MEL biosynthesis is the acetylation of the fully acylated mannosylerythritol lipids catalyzed by the acetyl-CoA-dependent acetyltransferase MAT1 (PubMed:16885300).  MAT1 displays a relaxed regioselectivity and is able to transfer acetylgroups to both positions C-4 and C-6 of the mannosyl moiety (PubMed:15932999).
What are the official names of this protein?
Acetyltransferase MATC1, Mannosylerythritol lipids (MELs) biosynthesis cluster protein MAT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RAS1_DROSE
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKMNKPNRRFKCKML
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: KATG_HALSA
Sequence: MENEDHNFGTSDWWPNQLDLEILDQNSQQVDPYGEDFDYAEAFEDLDLAAVKDDLEEMMTDSKDWWPADYGHYGPLFIRMAWHSAGTYRTFDGRGGAAGGRQRLPPVDSWPDNVNLDKARRLLWPIKQKYGRKLSWGDLIILAGNVALESMGFETYGFAGGRKDDYTPDEAVDWGPEDEWETTSGDRFDADGSLKWPLGNTVMGLIYVNPEGPNGEPDLEGSAKNIRESFGKMAMNDKETVALIAGGHTFGKVHGADDPEENVGAEPAAAPIEKQGLGWENEFGEGKGPDTITSGIEGPWNTTPTQWDMSYVDNLLEYEWEPEKGPGGAWQWTTKSGELNESAPGVQDPTDTEDVMMLTTDVALKDDPDYREVLETFQENPREFQQSFSKAWYKLIHRDMGPSERFLGPEVPEETMIWQDPLPDADYDLVDDEAVAALKSELLESELSIPQLVKTAWASASTYRDSDKRGGANGARIRLEPQRSWEVNEPEQLEAALSTYEDIQAEFNDARSDDMRVSLADLIVLGGNAAIEQAAADAGYDVDVPFEPGRTDATPEQTDVESFEALKPKADGFRNYLGDDAEREPEELLVDKAELLNLTADDMTVLVGGLRALGVTHGDSELGIFTDQPGTLTNDFFTTLLDMDYEWEAASEDREVFELRDRETGDVEWTGSRVDLLFGSNTRLRAIAEVYGSDADEELFVQDFVDTWSEVMKLDRFDLE
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Hydroperoxidase, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: HSK3_ASHGO
Sequence: MDQTKRRHYSQLSQQLQLLQKNLEATTQHVETMSVQCNEHLVNKLGKIQASWFIGGNRCFEQELLGKR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit HSK3, Outer kinetochore protein HSK3.
What is the protein family that this protein belongs to?
Belongs to the DASH complex HSK3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: SDK2_CHICK
Sequence: MKGLGVPAAALLWGGLSALLPPSLPADDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPFAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDARSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGQGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSNMLVRWSDIPEADCNGLILGYKVMFKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAMPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRIPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIGGFSSFV
What is the function of this protein?
Adhesion molecule that promotes lamina-specific synaptic connections in the retina (PubMed:12230981, PubMed:18216854).  Expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (PubMed:12230981, PubMed:18216854).
What are the official names of this protein?
Protein sidekick-2.
What is the protein family that this protein belongs to?
Belongs to the sidekick family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse.
Protein: LNT_BLOFL
Sequence: MFISKAKYFFQLILSLTFGICGVFAFSPYDFWPLSIISITGLLIIILSNITWKQIIWNTLFWGIGFFSVGLHWIYIGIDQFIPTHKNMNFFLIAFLIIYLTCYSVLFSIILVTLRLFITQWSFLSITAATLWLIIDRLRGNEFIGFPWLQFGYSQISGPIRGIGPLLGVEGITFCLVLISSLLALSIRTVQPSPYYISLIILACLYPLSWIQWYQVQPQRMTTIALVQGNINQHLYWNTENIQKTLKIYLQHTLPLLGKVKIIIWPESAIPGNELAHNELLVSLDYQLRKHHTYLITGIIDSRLINNSYYHHYNSIIVLGNTHDPYKYPSSNRYDKHHLVLCSERFPLQCLFEPVFRFFNIPIAFMKSGPYIQSQLNVYPIKMTASICYEIILGNQIRDNFKLDSDFLLTLANDVWFGCSIGPWQHLQIARMRALELGRPILFCTNNGVTAIINADGSIQSQLSQFISTTLITNISPTTGFTPYAQFGSWWLLIISILICIFIIYIQKNQLFKIFTFFKKNK
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCKG_ACIBS
Sequence: MTTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQEKHPGSYLANSDPSDVARVEDRTYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRTMYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGKAVYDVLGTDGEFVPCVHTVGAPLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQGWLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEVPANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWENPAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLGAKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETPIGFVPTYEDLNWEGTEFTKEQFDLITNQDKDQWVTEIESHTELFNKLGERLPKALKERQAALLEAVKTGF
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CHESB
Sequence: MDLIRQLEAEQAQKIAAKRTLPDFSPGDTLRVQVRVTEGNRTRVQAFEGVCIARSGSGLQENFTVRKISYGEGVERVFPVYSPLVEAVEVVRRGKVRRAKLYYLRDRRGKSARISENTGARARKLNDAEREAAAQERARIEAEKVAAAEALAAEKAAAEAAEAKSE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CH60_PORGI
Sequence: MAKEIKFDMESRDLLKKGVDALANAVKVTLGPKGRNVILSKTYGAPHITKDGVSVAKEIELECPFENMGAQLVKEVASKTNDDAGDGTTTATILAQSIIGVGLKNVTAGANPMDLKRGIDKAVKAVVTHIAGMAKEVGDDFQKIEHVAKISANGDENIGSLIAEAMRKVKKEGVITVEEAKGTDTTVEVVEGMQFDRGYISPYFVTNTDKMEVQMENPFILIYDKKISVLKEMLPILEQTVQTGKPLLIIAEDIDSEALATLVVNRLRGSLKICAVKAPGFGDRRKAMLEDIAILTGGTVISEETGLKLENATMDMLGTAEKVTVDKDNTTIVNGAGNKEGIASRITQIKAQIENTTSDYDREKLQERLAKLAGGVAVLYVGAASEVEMKEKKDRVEDALSATRAAIEEGTVPGGGTAYIRAIAALEGLKGENEDETTGIEIVKRAIEEPLRQIVANAGKEGAVVVQKVKEGKDDFGYNARTDVFENLYTTGVIDPAKVTRVALENAASIAGMFLTTECVIADKKEDNPAAPAMPGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.