PharMolix/UniProtQA huggingface dataset:
Protein: KUP_STRPZ
Sequence: MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQGGVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWLIIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLFGIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKHSGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVTYPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYLIKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTRIVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKRPKRAQVYWFVNVQVTDEPYTAKYKVDMVGTDYMVRVNLYLGFRMPQTVPRYLRTIVQDLMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMHTKASIKHVTASPMRWFGLQYSEVTLEVVPLILSDILKLPIKELVPVEDSEA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INV1_ORYSJ
Sequence: MGTRLLALAPWLLLLLLQLAGASHVVHRSLEAEQAPSSVPASIVSPLLRTGYHFQPPMNWINDPNGPLYYKGWYHLFYQYNPKGAVWGNIVWAHSVSQDLINWIALEPAIKPDIPSDQYGCWSGSATILPDGTPAILYTGIDRPNINYQVQNIAFPKNASDPLLREWVKPAYNPVATPEPGMNATQFRDPTTAWYADGHWRMLVGGLKGARLGLAYLYRSRDFKTWVRAKHPLHSALTGMWECPDFFPLQAPGLQAGLDTSVPSSKYVLKNSLDLTRYDYYTVGIYNKVTERYVPDNPAGDYHRLRYDYGNFYASKTFFDPVKHRRILLGWANESDSVTYDKAKGWAGIHAIPRKVWLDPSGKQLLQWPIEELETLRGKSVSVFDKVVKPGEHFQVTGLGTYQADVEVSLEVSGLEKAEALDPAFGDDAERLCGAKGADVRGGVVFGLWVLASAGLEEKTAVFFRVFKPAGHGAKPVVLMCTDPTKSSLSPDLYKPTFAGFVDTDISSGKISLRSLIDRSVVESFGAGGKTCILSRVYPSMAIGDKAHLYVFNNGEADIKISHLKAWEMKKPLMNGA
What is the function of this protein?
May play a role in sucrose partitioning during seed development and in stress response.
What are the official names of this protein?
Beta-fructofuranosidase, insoluble isoenzyme 1, Cell wall beta-fructosidase 1, Invertase 1, OsCIN1, Sucrose hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall. Note=Associated to the cell wall.
Protein: VATD_SULIL
Sequence: MSQKVLPTKINLIQFRRQLRLITVIKRLLENKREVLLLYLRTYASEYEKIYNEVNEEMKKVYESYLQAVASEGISNIEEIALSQKPSLEVSSSIKVIFGVKVPTIKLDKSTIPPKPFSDVETSPYLSESYEEMTEALNKIIELVELESTIRSLVSELRKTQRLINSIDNYILPFYRGSIKFIKQILEDRQREEFSRLKIIRRILQRRRESGSG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: RL6_LEIXX
Sequence: MSRIGRLPIDVPAGVDVKIDGQAVTVKGPKGELSLTVASPIEVKLEEGQVLVTRPDDERESRSLHGLTRTLLNNNIVGVTQGYSKGLEIVGTGYRVAQKGAGVEFALGFSHPVTVEPPAGITFTVEGNNKLTVAGIDKQAVGEVAANIRKIRKPEPYKGKGVRYAGEVVRRKAGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LIFO2_BURCE
Sequence: MTAREGRAPLARCAVVYGVVGLAAIAGVAMWSGAGWHRGTGTAGELPDAAAAGGAAAAPPQAALPASTGLPSSLAGSSAPRLPLDAGGHLAKSRAVRDFFDYCLTAQSDLSAAALDAFVVRQIAAQLDGTVAQAEALDVWHRYRAYLDALAKLRDAGAVDKSDLGALQLALDQRASIAYRTLGDWSQPFFGAEQWRQRYDLARLKIAQDRTLTDAQKAERLAALEQQMPADERAAQQRVDQQRAAIDRIAQLQKSGATPDAMRAQLTQTLGPEAAARVAQMQQDDASWQSRYADYATQRAEIESAGLSPQDRDAQIAALRQRTFTKPGEAVRAASLDRGAGSAQ
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: HCNB_PSEAE
Sequence: MNLRPVIVGGGSAGMAAAIELARRGVPCVLFDEASRPGGVVYRGPLRAGVDPAYLGARYTRMLEKLRRDFSACAGHIDLRLNSRVVGGDGQRLMVLDEAERLHEVEYSHLLLATGCHERSVPFPGWTLPGVMLLGGLQLQIKSGVVKPLGDTLIAGSGPLLPLVACQLHAAGVRVAGVYEACAFGRMARESLALLNKPQLFLDGLSMLGYLKLNGIPLHYGWGVVEASGDGELTEVTVAPYDEEWRPDLENARPVKASTLAVGYGFIPRTQLSQQLGLEHGFSDDGYLRAECNVWQQSSQPHIHLAGDMAGIRGGEAAMIGGRIAALSILLQREAIAPAEAIERRESHLARLEAIKRFRAGVERYTQRGARQVELARADTVICRCEQVTRGDIERALEQGVQDIAGLKMRTRAGMGDCQGRMCIGYCSDRLRRATGRHDVGWLRPRFPIDPIPFSAFQNLGTEA
What is the function of this protein?
A three-component membrane-bound flavoenzyme that catalyzes the formation of hydrogen cyanide, a secondary metabolite, by transfer of electrons to a cyanide-resistant branch of the aerobic respiratory chain.
What are the official names of this protein?
Hydrogen cyanide synthase subunit HcnB, HcnB, Glycine dehydrogenase (cyanide-forming).
What are the subcellular locations of this protein?
Cell membrane.
Protein: SOX9_MACMU
Sequence: MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
What is the function of this protein?
Transcription factor that plays a key role in chondrocytes differentiation and skeletal development.  Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6.  Also binds to some promoter regions.  Plays a central role in successive steps of chondrocyte differentiation.  Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes.  Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis.  Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes by lowering beta-catenin (CTNNB1) signaling and RUNX2 expression.  Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells and transactivating COL10A1 along with MEF2C.  Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO (FOXO1 and FOXO3) transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation.  Mechanistically, helps, but is not required, to remove epigenetic signatures of transcriptional repression and deposit active promoter and enhancer marks at chondrocyte-specific genes.  Acts in cooperation with the Hedgehog pathway-dependent GLI (GLI1 and GLI3) transcription factors.  In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells: involved in the lung epithelium during branching morphogenesis, by balancing proliferation and differentiation and regulating the extracellular matrix.  Controls epithelial branching during kidney development.
What are the official names of this protein?
Transcription factor SOX-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH2_SYNFM
Sequence: MGRKPVEALAMDMLHFEKQAYRQGFQLVAGIDEVGRGPLAGPVVAAAVVVPAGVRLPGVADSKKLSAGQRESCCEDILSCGCDVGIGRVEPSEIDRVNILQATFQAMIAAVAGLKTPPHCLLIDGPYELPLFIAQKGIPQGDAKSLSIAAASIVAKVHRDRLMCEYHLKYPVYGFDRNKGYGTARHLDALRRYGPCPIHRLSFGGVRASEGEGLETAAGRQSSEGKKGRRPRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRVB1_GADCH
Sequence: MSFAGVLADADVKAALAGCAAADSFNYKTFFKACGLAAKSHEEVKKAFFVIDQDQSGFIEEDELKLFLQTFGAGARELTAAETKAFLAAGDEDGDGMIGVDEFVTLVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta-1.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: PTH_GEOKA
Sequence: MKLFVGLGNPGKEYEQTRHNVGFFVIDELAKRWNVSLKTAKFRGLFGTASVSGEKVALCKPLTYMNLSGECVRPLMDYYDIAIDDVIVIYDDLDLPPGKIRLRLKGSSGGHNGVKSLIHHLGTEQFKRIRIGIGRPAGGQPVTDYVLGRFTEEEKPAVDKAVLRAADACEQAVKAPFIQVMNDFNE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_VIBCM
Sequence: MSDGLQRCFVLHRRPYSESSLILDVFSEEYGRVTLMAKGARGKRSNLKGALQPFTPLLLKWSGNGSMKTLRQAEPISLGLPLSGVYLYSAMYINELVDRVLMPEVASPGLFHDYLFALTELAQSTNPEPALRRFELALLAAMGYGVDFLHCAGTGEPVSPDMTYRYREQKGFIASVRRDNLTFLGNELIAISERRFTSKEQLQAAKRFTRLALKPYLGGKPLKSRELFRQTTLPRARSTEE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PTYBC_ECOLI
Sequence: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNLD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is responsible for growth on MurNAc as the sole source of carbon and energy.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPP_EXISA
Sequence: MGKVHVYDHPLIQHKMTIMRKVETGTKQFRELVDEVSSLMAYEITRSLPLTDVEIETPVSVSTQKMIAGKKLGIVPILRAGLGMVDGFLKMMPNVKVGHIGLYRDPETLEPHEYYLKLPTDVTERDFIVVDPMLATGGSAVDAIASLKKHGAKSIKLACLCAAPEGVERVQAEHPDVEIYLAALDEKLNDHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: FER_CLOSM
Sequence: AYKITDGCINCGACEPECPVEAISESDAVRVIDADKCIDCGACANTCPVDAIVEG
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: HISZ_PARXL
Sequence: MSTWLLPENIADVLPSEARKIEELRRHLLDRFRSYGYEMVMPPLLEYIESLLTGGGHDLNLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGNVAHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALRLAGLAKVRLDLCHAGVLAALIEAEPAAAELGQSLYDALAGKDVPRLVELTANLTPVIRDALRALPRLYGDASVLDEARARLPNMPAIARALDDLAFLASQVDGAEVMIDLADLRGYAYHSGVMFSAYVDGVPNAVARGGRYDHVGQAYGRARAATGFSLDLREVARISPVEARSSAILAPWQHDEALRVSVAALRDAGEVVIQALPGHEHDLDEFAFDRVLVERSGNWVVEPRA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_PSEF5
Sequence: MLILRGAPALSAFRHSKLLEQLSQKVPAVSGLYAEFAHFAEVTGVLTGDEQQVLARLLKYGPSVPVQEPTGRLFLVLPRFGTISPWSSKASDIARNCGLAKIQRLERGIAFYVAGEFSEAEAQLIADALHDRMTQIVVANLEQAAGLFSHAEPKPLTAIDILGGGRAALEQANSELGLALAEDEIDYLMNAFQGLKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGMIKNTYQMHNEGVLSAYKDNAAVIVGSVAGRFYPNPETRQYGAVQEPVHILMKVETHNHPTAIAPFPGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKPERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPRGDEVRGYHKPIMLAGGMGNIRDEHVQKGEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPEMERRCQEVIDRCWQLGDNNPISFIHDVGAGGLSNAFPELVNDGGRGGRFELRNIPNDEPGMAPHEIWSNESQERYVLAVGAADFERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNSPVDMPLEVLLGKAPRMHRSAVRENELGDDFDPSTLDIAESIERVLHHPAVASKSFLITIGDRTITGLVARDQMVGPWQVPVADVAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAIGETLTNIAASRINKISDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMSMATRWNEEGVDKSVTSPLSLIVTGFAPVADIRQTLTPQLRMDKGTTDLILIDLGRGQNRMGASILAQTHGKLGSQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLVSAVEMAFAGHCGLNLSLDAVAENTAEIAAILFNEELGAVIQVRQDATPDVLAQFSAAGLGDCVAVIGQPINNGEVSISYNGESVFTGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDVVLEEDNPGLSVKLGFDVNQDIAAPYIKKGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDVHMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERTDSFTLGVCNGCQMMSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESNSIFLQGMAGSRMPIAIAHGEGHAEFESEEALLEADLSGCVALRFVDNHGKVTERYPANPNGSPRGITGLTSRDGRVTIMMPHPERVFRAVQNSWRPDEWNEDGAWMRMFRNARVWVN
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I68A5
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIMVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNAKIEPFLKTTPRPIRLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRPCLLQSLQQIESMVEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: HOR7_HORVU
Sequence: QPQQSYPVQPQQPFPQPQPVPQQRPQQASPLQPQQPFPQGSEQIIPQQPFPLQPQPFPQQPQQPLPQPQQPFRQQAELIIPQQPQQPLPLQPHQPYTQQTIWSMV
What is the function of this protein?
Sulfur-poor seed storage protein.
What are the official names of this protein?
C-hordein, PCP387.
Protein: C5171_DICDI
Sequence: MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI
What are the official names of this protein?
Probable cytochrome P450 517A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IGBP1_MOUSE
Sequence: MAASEDELLLPRLPELFETSKKLLEDVEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFSRNEDLEEIASTDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFVHFLTQCHCYHVAEFQLPQTKTNSAENNTASSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVREYHLLHLRRWIAVSLEELESIDQEIKILKEKDSPREETACHSSLPEKPPMKPFILTRNKAQAKVFGTGYPSLATMTVSDWYEQHQKYGVLPDRGIAKPASADFQRAAQQQEDQEQKDEESEEKALHRMREWDDWKDTHPRGYGNRQNMG
What is the function of this protein?
Associated to surface IgM-receptor; may be involved in signal transduction.  Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
What are the official names of this protein?
Immunoglobulin-binding protein 1, Alpha4 phosphoprotein, CD79a-binding protein 1, Lymphocyte signal transduction molecule alpha 4, Protein phosphatase 2/4/6 regulatory subunit, p52.
What is the protein family that this protein belongs to?
Belongs to the IGBP1/TAP42 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_HYPBU
Sequence: MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLALQRPVIVEDAGLFVEALGGFPGPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSGGVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAEMETQEKNKFSHRGKAARELCRWLRQYGPPR
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: KPYK_BACLI
Sequence: MRKTKIVCTIGPASESVEKLTQLMEAGMNVARLNFSHGDFEEHGARIKNIREAAGKLGKDIGILLDTKGPEIRTHTMENGSIELAAGSQLIVSMDEVIGTPDKISVTYDGLIHDVSVGSTILLDDGLVGLEVTDINKDKREIVTKVMNSGTLKNKKGVNVPGVSVNLPGITEKDANDIVFGIEQGVDFIAASFVRRPSDVLEIRELLEEHNAADIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGNYPVEAVQTMHNIASRSEEALNHKKILSARSKQVSMSITDAIGQSVAHTAINLDVNAIVTPTESGHTARMISKYRPQAPIVAVTVNDAVSRKLSLVFGVFATSGQNHSSTDEMLEKAVQKSLDTGIVRHGDLIVITAGAVGEAGTTNLMKVYVVGDVVAKGQGIGRKSAFGEVVIAQNAQEAAKKMKDGAVLVTKSTDRDMMASLEKAAALITEEGGLTSHAAVVGLSLGIPVIVGMENATSILKEGEDITVDSARGAVYKGRASVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: RISB_GEOSW
Sequence: MKVMEGNLVGTGLKIAIVISRFNEFITSKLLSGAMDGLKRHGVNENDVTVAWVPGAFEIPLIAKKLAESRQYDAVIALGAVIRGATSHYDYVCNEVAKGVSHAALSTGTPVIFGVLTTDTIEQAIERAGTKAGNKGWEAAVSAIEMANLLRTFA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HIS1_AERS4
Sequence: METQRLRIAMQKSGRLSQDSQALFKSCGLKINLREQRLIAHVENMPIDILRVRDDDIPGLVMEGVVDLGIIGENVLEEAQLIRASQGLPAQVKTLKQLDFGGCRLSLAVPDDVAYTGPESLAGKRIATSYPGLLKRFFDEKGLNFKSVMLGGSVEVAPRAGLADAICDLVSTGATLEANGLKEVEVIYRSKAVLVQAPNPLNEAKQKLIDKLLPRIQGMQQARESKYIMLHAPKDKLDAITDLLPGAERPTIMQLAGDTNQVALHVVSSETLFWETMEQLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_PARDP
Sequence: MDGDIRKNSYDDGSMDALTGEQSIRNFNINFGPQHPAAHGVLRMVLELDGEIVERADPHIGLLHRGTEKLMESRTYLQNLPYLDRLDYVAPMNQEHAWCLAIERLTGTVIPRRASLIRVLYSEIGRILNHLMGVTTGAMDVGALTPPLWGFEAREELMIFYERACGARLHAAYFRPGGVHQDLPPDLLDDIEEWCERFPKLVDDLDTLLTENRIFKQRLVDIGIVTEADALDWGYTGVMVRGSGLAWDLRRSQPYECYDEFDFQIPVGRNGDCYDRYLCRMAEMRESCKIMQQAVQKLRAEPAGDVLARGKLTPPRRAEMKRDMESLIHHFKLYTEGFKVPAGEVYAAVEAPKGEFGVYLVADGTNKPWRAKLRAPGFAHLQSIDWMSRGHMLADVPAIIATLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I, subunit 4, NADH dehydrogenase I, subunit D, NADH-quinone oxidoreductase subunit 4, NQO4, NDH-1, subunit 4, NDH-1, subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y2486_GEOTN
Sequence: MEHGDRHITVVDEQGNEQLCEILFTFESDDFGKSYVFYYPVSAEAEDEDGETEVHVSAFIPGDENEEGELLPIETEEEWDMIEEVWNTFCAEQEEGEE
What are the official names of this protein?
UPF0473 protein GTNG_2486.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.