PharMolix/UniProtQA huggingface dataset:
Protein: FAEB2_ASPTN
Sequence: MAPIHYLLPIITLGSAALARQDAFEAKCHSFANKIHLPNVHVNFASYVPGGTNLTLADNPSSCGATSQSVSADVCRVAMAVATSNSSEITLEAWFPRNYTGRFLSTGNGGLSGCIQYYDMAYTTGFGFATVGANNGHNGTSGEPFYHHPEVLEDFAYRSIHTGVVIGKKLTKMFYEEGFNKSYYLGCSTGGRQGFKSVQKYPNDFDGVVAGAPAFNFANLISWSAHFYPITGPPGSDTYLSPAMWKVAHDEIIRQCDQIDGAKDGIIEDPSLCNPIMETIICKPGASSDNCLSAAQAKTVREVLYPLYGVNGTLLYPRMQPGSEVLAAPIMYNGQPFAYSTDWYRYVVYNDPNWNGTTFDVQDAAAALAQNPYNIQTWDADLTPFRKSGGKVLTYHGLQDQLISSENSKLYYARVAETMGMPPEELDEFYRFFQISGMGHCGGGDGAYGIGNGLATYSGKDPENNVLMAMVQWVEKGIAPETVRGAKFANGPGSTVEYSRKHCRYPRRNVFKGPGNYTDENAWECVV
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B-2, Ferulic acid esterase B-2, FAEB-2.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RM37_MOUSE
Sequence: MALASGPALRALAGSGRLGLGGYGTPKRGAYEWGVRSTRKPEPRPLDRVYEIPGLEPITYEGKKHFVPWLARPIFPPWERGWNDPRFHRAAPIHEQTLYKEEPCYIFHQRCRLLEGMKQALWLTKTKLIEGLPKKVLSLVDDPANHIENQEQRVLDIISHARLWHSTEDIPKRETYCPLIVDSLIQLCKSQILKHPSLARRTSAQNCTLATTWNRESLLLQVRGTSSTILSAKDPLPVIASREEVEATRSHVLETFYPISPTIDLQECHVYEVKDDTGFQEGYPYPHPHTLYFLEKANLRPQRFLPEQLRAKMLLFAFANALAQARLLYGNTAKVLEQPIVVQSVGTDGRVFQFLVLQLNTTDLASSEGVKNLVWTDSDQLLYRHFWCRPVIKKKVVVEPVGPVDFQPETFRKFLALYLHGVV
What are the official names of this protein?
39S ribosomal protein L37, mitochondrial, L37mt, MRP-L37.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL37 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS4_POLNA
Sequence: MARYLGPKAKLSRREGTDLFLKSARRSISDKAKFDSKPGQHGRTSGTRTSDYGLQLREKQKVKRMYGVLEKQFRRYFEEADRRRGNTGANLLSVLESRLDNVVYRMGFGSTRAEARQLVSHKAMTVNGQSVNIPSYMVKAGDVIAVRDKSKKQTRIAEALELAKQVGLPAWVDVNADKGEGTFKKVPDRDEFAADINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL7_STRAT
Sequence: MALTQDELLAEFEGMTLIQLSEFVKAFEEKFDVTAAAAAPVVVAGGAAGGAAAEAEEEKDEFDVILTGAGDKKIQVIKVVRELTSLGLKEAKDLVDGTPKPVLEKVNKEAADKAAEALKGAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MBLC2_CHICK
Sequence: MSALEWFAHKPLGSGIFWIQERFYESGNRANIWLVRGSQRDLVIDAGLGLRSLPDYLRAAGLLAPPDGAGPRPLLAVATHVHFDHSGGLQHFEEVAVHSAEAAALLRGDNYEAVTWLSDREVTRPPRPGWRARHFCVPPVRPSRLLQEGDVISLGDRQLTVMHMPGHSRGSICLHDREHKILFSGDVVYDGSMIDWLPYSNVSDYVVSCQRLMELVDRGLVEKVLPGHFNMFGAERLYRLASNYISKAGICHKVSTCAMRSIASIALHLTNSRGTSS
What is the function of this protein?
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.  Has an acyl-CoA thioesterase activity towards the long chain fatty acyl-CoA thioester palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA).  Displays a substrate preference for fatty acyl-CoAs with chain-lengths C12-C18.
What are the official names of this protein?
Acyl-coenzyme A thioesterase MBLAC2, Acyl-CoA thioesterase MBLAC2, Beta-lactamase MBLAC2, Metallo-beta-lactamase domain-containing protein 2, Palmitoyl-coenzyme A thioesterase MBLAC2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor.
Protein: TRMD_CAMJR
Sequence: MKFSFVSLFPNLMEFYFQDSILARAKEKKLFKLNFYNPRDFSKNSYHKVDDYKIGGGAGLLMQAEPMYEVLRSIQEKKENPYFIFLNPSGKTFNQKDAKRLSKKEHIVFVCGRYEGIDERVLEIFANEIFSIGDFILTGGELPALVMCDAILRNVNGVLGNMESLKEESFENNLLEAPAFSKPFIFEKKNKKFYTPSEFLKGNHARIASLKTTLASCKTKFFRPDLFLEHERKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACL_ECOL5
Sequence: MDYEFLRDITGVVKVRMSMGHEVIGHWFNEEVKENLALLDEVEDAARTLKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: PHS_ACIAC
Sequence: MTSSSMLTKKDWSAHARRALSPTEIVTRLADLQGWALSGDGAAVAIEKTYRFANYYETISFVNAVAFIANAQDHHPDLSVHYDRCVVRLNTHDVKGISTTDLECAARFDALLAASE
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: HFQ_LEPBA
Sequence: MSAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAISTIIPAKPIKLHSEETPKEAGGV
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: OBP71_ANOGA
Sequence: MCGAIVLLLLVGTSPAPVEGLRCRTGEGPSADDVKRIVRTCMNKITNAGTMGEWGQRDRNGEEQQMMRDYGRSHRRRKRQYYGGQTSGSSSSGSAGEHSYNGRASPQYGEAGQGGNGTRSGGNSSSSSSSTIERDRACLMQCFFEEMKATNADGFPEKHKVLHVITKDIREHELREFYVDSIQECFHMLGLDNRLKDKCDYSMRFVTCLSDRFETNCDDWESVTSAMF
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 71.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: BTN2_YEAST
Sequence: MFSIFNSPCVFEQLPSFSQPLHSRYFDCSSPVSYYPECKRRKAIKANLRAPKKSDANCSEPLRYALAETPNGYTLSLSKRIPYELFSKYVNEKLGELKENHYRPTYHVVQDFFGNQYYVEDEADEDALLRSALKDLDFRAIGKKIAKDLFQDYEIELNHRGDELSILSKKDKIFKEFSLDQVFEDVFVIGCGVENIDDGSREKYALLKIGLVKHEEEISEGGINEPKMPIIESKIDESHDDVNMSESLKEEEAEKAKEPLTKEDQIKKWIEEERLMQEESRKSEQEKAAKEDEERQKKEKEARLKARKESLINKQKTKRSQQKKLQNSKSLPISEIEASNKNNNSNSGSAESDNESINSDSDTTLDFSVSGNTLKKHASPLLEDVEDEEVDRYNESLSRSPKGNSIIEEI
What is the function of this protein?
V-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi.  Modulates the rate of arginine uptake.  Involved in pH homeostasis.  Required for the correct localization of IST2.  May be involved in ion homeostasis together with IST2.
What are the official names of this protein?
Protein BTN2, Batten disease protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome.
Protein: PELB_ASPFU
Sequence: MKYQDLLAIAGCIANAGAVSVSGAAEGFAKGVTGGGSATAVYPSTTAELVSYLGDSEARVIVLTKTFDFTGTEGTTTATGCAPWGTASACQLAINQNNWCTNYEPNAPSVSVTYDNAGILGITVKSNKSLIGSGSSGVIKGKGLRIVSGASNIIIQNIAITDINPKYVWGGDAITIDNADMVWIDHVTTARIGRQHLVLGTSASNRVTISNNYFNGVSSYSATCDGYHYWGIYLDGSNDLVTMKGNYIYHFSGRSPKVQGNTLLHAVNNYWYDSSGHAFEIGSGGYVLAEGNVFQNIDTIVQSPVDGQLFTSPDSNTNKVCSTYLGHVCQVNGFGSSGTFSQADTGFLSNFAGKNIASASAYTAVQSTVPSSAGQGKI
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase B, PLB.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_RICFE
Sequence: MFAVIKAGGKQYKVDRNSIIKVEKIDGELGSKIQFDQILMIGEYSKPSFIGTPIVKGAVVTAEITNQLKDNKIIVFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FTHS_VIBPA
Sequence: MQSDIEICRNTPLSSIDVIAEKAGLLPEEFDTHGKYKAKVHPKCLARLNDNQNGKLVLVTAITPTPLGEGKTVTTIGLAQGLAKLKQSVMACIRQPSMGPVFGIKGGAAGGGYSQVAPMEELNLHLTGDIHAVTAAHNLASAALDARLFHEQREGYDAFEARTGLKALKIDVESITWKRVMDHNDRALRMVKIGLNEHGKTINGFERNEGFDISAASELMAIIALAKNLKDLRQRIGKIVVAYDLDGQPITTEDLQVAGAMAVTLKEAIAPTLMQTLEGVPTLIHAGPFANIAHGNSSIIADEIALKLSRYTVTEAGFGSDMGFEKACNIKAAAANKAPDCVVIVATLRGLKANSGHYDLRPGMAIPDSIFSPDQAALVAGFENLKWHIKNVHKYGIPAVVAINQFPQDCEQELTALQDLIHAFDPNVKVAISTAFAQGGEGTRDLAQYVVDACEKTTNFRPLYQKHQSLQEKLMSVCEAGYGATNVEMSELATKQLAHFEKLGFNELAVCIAKTPLSVTTDSSVKGAPVGFTVPIRELRLCAGAGFVYALSGSVMTMPGLPDKPAFMNLDLDEDGNIIGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: VKT6_ANEVI
Sequence: MVFLLCFFLVADVSYGINGDCELPKVVGPCRAGFRRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVCGVRSRDSPKEN
What is the function of this protein?
Serine protease inhibitor that inhibits both tissue and plasma kallikreins.  Has hemolytic activity.  Inhibits voltage-gated potassium channels (Kv).
What are the official names of this protein?
U-actitoxin-Avd3i, U-AITX-Avd3i, AsKC6.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RL9_BRADU
Sequence: MEVILLERVNKLGQMGEVVKVRDGYARNFLLKRGKALRATADNRAKYDGMKADLEARNLASKAEASKVAEKIQGKNIIVIRQASEAGQLFGSVNVRDIVVAFEADGISLARPQIQLDAPIKTIGKHTITVAVHPEVEVEITVTVARSQDEAERINRGEDISTRNEDRDAAAEAIAAAGEFFDPEAQHDDVEPAPAAEETEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SLYX_ACTPJ
Sequence: MTTENDLLNRIAELETKVAFQEITLEELNQALIHHQLALDKLQTQMRHFAEKLKGAQVSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: VNPB_HOPST
Sequence: SGSKTAKIGDGCFGVPIDHIGSTTDLGCGRPRPKPTPRGS
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Natriuretic peptide HsNP-b.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3L21_DENJA
Sequence: RTCYKTYSDKSKTCPRGEDICYTKTWCDGFCSQRGKRVELGCAATCPKVKTGVEIKCCSTDYCNPFPVWNPR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Djk2a, Alpha-EPTX-Djk2a, Long neurotoxin 1, Toxin V-III-N1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OXLA_APLCA
Sequence: MSSAFLLLACALVISVHADGVCRNRRQCNKEVCGSSYDVAIVGAGPGGANSAYMLRESGLDIAVFEYSDRVGGRLFTYQLPNTPDVNLEIGGMRFIEGAMHRLWKVISELGLTPKVFKEGFGKEGRQRFYLRGQSLTKKQVKSGDVPYDLSPEEKANQGRLVEYYLEKLTGLQLNGGPLKREVALKLTVPDGRFLYDLTFDEALDLVASPEGKEFARDTHVFTSEVTLDASAISIFDDHLGEDYYGSEIYTLEEGMSSVPQGLLQTFLDAAKSNEFFPNNHLKALRRRTNGQYVLYFEPTTSKDGQTTINYLEPLKVVCAQRVILAMPVYALRQLDWSQLRNDRATQAYRAVRPMPASKVFMTFDQPWWLQNERKSWVTKSDALFSQMYDWQKSEASGDYILIASYADGLKAQYLRELKNQGEDIPGSDPGYNQVTVPLKDAILEHLTEAYGVERDSIPEPVTAASQFWTDYPFGCGWITWRAGYHFDDVISTMRRPSLKDEVYVVGSDYSWGLISSWIEGALETSENVINDYFL
What is the function of this protein?
Catalyzes the oxidative deamination of positively charged L-amino acids L-Lys and L-Arg and, much less efficiently, of amino acids L-His and L-Tyr.  Has antimicrobial activity.  Inhibits growth of Gram-negative bacteria E. coli strain MC4100 (MIC=0. 62 ug/ml), E. coli strain C921-b2, S. typhimurium strain AA 140 (MIC=0. 62 ug/ml), P. aeruginosa strain PAO1 (MIC=0. 31 ug/ml) and V. harveyi strain BB170 (MIC=0. 25 ug/ml).  Inhibits growth of Gram-positive bacteria S. aureus strain 6835 (MIC=0. 31 ug/ml), S. pyogenes strain NZ131 (MIC=0. 62 ug/ml), B. subtilis strain 168 (MIC=2. 50 ug/ml) and B. subtilis strain WB600 (MIC=2. 50 ug/ml).  The antibacterial effect can be bacteriostatic, mediated mostly by H(2)O(2), as well as bactericidal.  The latter appears to be due to unstable intermediates generated from alpha-keto-epsilon-aminocaproic acid, an intermediate of escapin-deaminated L-Lys, and H(2)O(2).  The bactericidal effect is stronger at lower pH levels.  Intermediates generated from L-Arg have no bactericidal effect.  Inhibits growth of yeast species S. cerevisiae strain BY4761 (MIC=5. 0 ug/ml) and C. krusei (MIC=5. 0 ug/ml).  Inhibits growth of C. sphaerospermum in a lysine-dependent manner.  As components of ink, products from escapin's enzymatic activity may play a role in deterring eukaryotic predators.
What are the official names of this protein?
L-amino-acid oxidase, LAAO, LAO, Escapin.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: H8A08_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYASGSEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 8, U3-TRTX-Hhn1a, Hainantoxin-VIII.8, HNTX-VIII.8, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MNN21_CANAL
Sequence: MFQQLTYRLRLFRRRHKYIFINSIFLSVIIIFLIYSYWSNLPAEDNSAIINEKGTYHRSLWESITMALFPPKTKPFEEKKPQVNPNNNQEVGVESGASEISQHKQQQQQQQHAKEPTTKTSSKSLVSDEAYQLNLKLINEQQEKYNRLHPFEQKRLQQGYEFFDNIFKIFYQAKPSVSQLNTYPSKKRIYHARFDSLADDDTIFSEKYLSQFLQLSNEELAAMKKSHKYVVENLPEDAPDGLYKKNGIVYVAGGSFNWLTLLSIKSLRAVGCHLPIEVFIPKIEEYESDLCNRILPELDARCIYMKNQLMNPNKDNSDSFANKFEFKGYQYKALAILLSSFENVLLLDSDNIPAHSPEELFENDPFKSYGLVVWPDYWKRATSPYYYNIADIDVSEKYLGSKYNEVEGQYTDLSVEKGSVELDKIPLHQRLGSIPDPTSESGQLLISKKTHLKPLLLALYYNLYGPSHYYPLFSQGSDGEGDKETFLAATVTLGKRYYQVAKFLVSLGHFKVPGGDFEGCGMGQFDPQQDLEYIKLREQYAKIPEKDKEKQHKFKLQHQVLEKGPEILFVHANFPKLNPWKLKQEKKIFDAKGNRVRLYGPGMIKRIGYDFEWFQWEGMKYLLCIYDVNLQIFQDVKKSDLCDEILEHLRFLESTQNITD
What is the function of this protein?
Alpha-1,2-mannosyltransferase required for cell wall integrity.  Responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides.  Addition of alpha-1,2-mannose is required for stabilization of the alpha-1,6-mannose backbone and hence regulates mannan fibril length; and is important for both immune recognition and virulence.
What are the official names of this protein?
Alpha-1,2-mannosyltransferase MNN21.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: FEM1B_XENLA
Sequence: MALDGLAGYVYKAAAEGRVLTLAALLLHRTEPEIRTLLSTVTQHGGQRSTPLIIAARNGHSKVVRLLLEHYKVDVQQTGTVRFDGYIIDGATALWCAAGAGHYEVVKLLVSHEANVNHTTVTNSTPLRAACFDGRLDIVRFLVENNANISIANKYDNTCLMIAAYKGHSDVVHYLLRQHADPNARAHCGATALHFAAEAGHLDIVRELVKWKAAMVVNGHGMTPLKVAAESCKADVVELLLAHSDCDAKSRIEALELLGASFANDRENYNITKTYQYLYLAMLERFRDPSNILHKEVLPPIEAYGMRTECRNPQELGAILHNTDDLHLEGLIVRERILGSDNIDVSHPIIYRGAVYADNMQFEQCIKLWLHALQLRQKGNRNTHKDLLRFAQVFSQMIHLNEPVKSRDVERVLECSVLEIERGIARIQNPQEPDAHSTLENHECNLYTFLYLVCISTKTCCSEEEQPCINKQIYRLVHLDPRTREGGSLLHLAVDSGTPVDDFHTNDVCSFPSAPVAKLLIDCGANVNAVDQMGNSPLHVIVQYNRPISDFLTLHAIIISLVEAGAHTDMTNKEKKTPLDRSTTGVSEILLKTQMKLSLKCLAARAVRLHNIKYQNQIPRTLEEFVEFH
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(FEM1B) complex specifically recognizes proteins ending with -Gly-Leu-Asp-Arg, leading to their ubiquitination and degradation.
What are the official names of this protein?
Protein fem-1 homolog B, FEM1b, FEM1-beta.
What is the protein family that this protein belongs to?
Belongs to the fem-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GIF3_ARATH
Sequence: MQQSPQMIPMVLPSFPPTNNITTEQIQKYLDENKKLIMAILENQNLGKLAECAQYQALLQKNLMYLAAIADAQPQPPAATLTSGAMTPQAMAPNPSSMQPPPSYFMQQHQAVGMAQQIPPGIFPPRGPLQFGSPHQFLDPQQQLHQQAMQGHMGIRPMGLNNNNGLQHQMHHHETALAANNAGPNDASGGGKPDGTNMSQSGADGQGGSAARHGGGDAKTEGK
What is the function of this protein?
Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues (By similarity).  Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (By similarity).  GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner.
What are the official names of this protein?
GRF1-interacting factor 3, AtGIF3, Transcription coactivator GIF3.
What is the protein family that this protein belongs to?
Belongs to the SS18 family.
Protein: CLPP1_THEFY
Sequence: MSEFNFDPYRRYGGGMAPMAPQSRYVLPSYIERTAYGVKEMNPYNKLFEERIIFVGVQIDDTSANDIIAQMMTLEHIDSDRDITLYINSPGGSFTSLMAIYDTMQFVRPDIQTVCVGQAASAAAVLLAGGTKGKRTALPNSRILIHQPATEGTHGQASDVEIMANEIMRIRHQLETILAKHTGRSVEEISRDIERDKILTAEEAKEYGIVDDVLPYRKASLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNK_DROME
Sequence: MLANETNKLLLSSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNYCTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQDQRPPVYDIKELETLQNAESTLDSTNALNALDKERNLMNEDPKWQDTNYVLANYKTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSMDDPRENSLSASLANTSLLTRSSAPINIPNTTLSNSINDFNSGSFAVNIPSSSLTYSPTNHANLFNVDAFNYGGSNKLSNSLSATQNDSSLFFPSRIISPGFGDGLSISPSVRISELNTIRDDINSSSVGNSLFENTLNTAKNAFSLQSLQSQNNSDLGRITNELLTKNAQIHKLNGRFEDMACKLKIAELHRDKAKQEAQEWKERYDLAQIQLNLPAELRDLSIQKLKQLQSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYCQVPVITTHT
What is the function of this protein?
Essential for late larval/early pupal development.
What are the official names of this protein?
RING finger protein unkempt.
What is the protein family that this protein belongs to?
Belongs to the unkempt family.
Protein: ECCE1_MYCTO
Sequence: MRNPLGLRFSTGHALLASALAPPCIIAFLETRYWWAGIALASLGVIVATVTFYGRRITGWVAAVYAWLRRRRRPPDSSSEPVVGATVKPGDHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEELLSVHCPDLEADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSFDDYDHATDIGFVREKWSMIKGRDAYTAAYAAPGGPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPRGFARLFGGQRPALQGQHLVANRHCQLPIGSAGVLVGETVNRCPVYMPFDDVDIALNLGDAQTFTQFVVRAAAAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGPHPGIDRVILRHNVIGTPRHRQLPIRRVSPPEESRYQMALPK
What is the function of this protein?
Part of the ESX-1 specialized secretion system, which delivers several virulence factors to host cells during infection, including the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10).
What are the official names of this protein?
ESX-1 secretion system protein EccE1, ESX conserved component E1, Type VII secretion system protein EccE1, T7SS protein EccE1.
What is the protein family that this protein belongs to?
Belongs to the EccE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IPT_PSESS
Sequence: MKIYLIWGATCTGKTEHSIKLSKSTGWPVIVLDRVQCCFDIATGSGRPHPEELQSTRRIYLDNRRISEGVISAEEANDRLKLEVNKHIDSGGVILEGGSISLLKLISKDPYWCDRFIWSQHRMRLQDTDVFMDKAKARVRRMLVGSTETTGLLDELVAAQSDLNAKLAIQDIDGYRYIMNYAQARRLSITQLLNVMTGDMKEELINGIALEYYEHAKWQERDFPAEWLAERSTR
What is the function of this protein?
Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones.
What are the official names of this protein?
Adenylate dimethylallyltransferase, Dimethylallyl transferase, Isopentenyl transferase, Trans-zeatin producing protein.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl transferase family.