PharMolix/UniProtQA huggingface dataset:
Protein: SC61A_WICAO
Sequence: MSSFRVLDLVKPLTGYLPEVIAPERKVPFNQKLMWTGVTLLIFLVMSEIPLYGIVSSESSDPLFWLRMMLASNRGTLMELGISPIVSSGMVFQLLQGTQLLDVNLESKTDRETFQTAQKLFAILLSIGQATVYVLTGIYGRPSDLGVGVCLLLILQLVFAGIIVILLDELLQKGYGLGSGISLFMATNICEQIFWKAFAPTTVNNGRGDEFEGAVVALFHLLSVRKDKRRALVEAFYRQNLPNIFQLLATFIVFFLVVYLQGFRYEIPVRSTRQRGQNGLYPIKLFYTSNTPIMLQSALTSNFFIISQMLFQRFPLNPVVRLFGVWDARPGSAQLFASNGLAYYIQPPLSLTEALLDPIKTVIYVSFVLSVCALFSKTWIEISGTAPRDVAKQFKDQGLVIAGRRETSVYKELKRIIPTAAAFGGASIGALSVACDLLGTLGSGTSILLAVTTIYSYYEIAAKEGGFQKHIVEGFSEAF
What is the function of this protein?
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER.  It is required for assembly of membrane and secretory proteins and is essential for cell growth.  It interacts with other membrane proteins required for protein translocation.  Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event.  A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
What are the official names of this protein?
Protein transport protein SEC61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ENV_XMRV4
Sequence: MESPAFSKPLKDKINPWGPLIIMGILVRAGASVQRDSPHQVFNVTWKITNLMTGQTANATSLLGTMTDTFPKLYFDLCDLVGDNWDDPEPDIGDGCRSPGGRKRTRLYDFYVCPGHTVLTGCGGPREGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPKGQGPCFDSSVGSGSIQGATPGGRCNPLVLEFTDAGKRASWDAPKTWGLRLYRSTGADPVTLFSLTRQVLNVGPRVPIGPNPVITEQLPPSQPVQIMLPRPPRPPPSGAASMVPGAPPPSQQPGTGDRLLNLVEGAYQALNLTSPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVTSQHKLTLSEVTGQGLCIGAVPKTHQALCNTTQKTSDGSYYLASPAGTIWACSTGLTPCLSTTVLNLTTDYCVLVELWPKVTYHSPNYVYGQFEKKTKYKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATKQFEQLQAAIHTDLGALEKSVSALEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGVVRDSMAKLRERLNQRQKLFESGQGWFEGLFNRSPWFTTLISTIMGPLIVLLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKSIDPEEVESRE
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: TOP6A_PYRHO
Sequence: MKLKRQKPKEKFSYDPQKVLKKLEDLAWKILEEAKSGKNPYFDVPTRGLNNVYFDEESRLIRLGDRLSRRYFLNVAHARKFMQTLILMAYIKRLVSEGKHASLREAYYANKHTVPGTRENTFEDQSESDPIIEDLERMLGVLREEMHITADRRGYIYGDIVIKDGEDEFNASKLGTGGWAVPGTVEHIQFPEINVDYVLVVETAAMADRLIEEKYPKRENCLIVATQGQASRGVRRLIHRLHYEEGLPIIVFTDGDPYGWYIYSTIKRGSINLAYLSEKLATPDAKFVGMTMDDIKEYNLENVTEKLKGIPPDKKGGPTGDYKRLIEELNYPWFQDKEWQRQLKLALKWGVRIEQQALANKSLEFVAKEYLPEKIREGKLLP
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: SECA1_STAAS
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RPO2_SACS2
Sequence: MASNLTIDERWRVIEAYFKSKGLVRQHLDSYNDFVRNKLQEIIDEQGEIPTEIPGLKVRLGKIRIGKPRVRESDRGEREISPMEARLRNLTYAAPLWLTMIPVENNIEAEPEEVYIGDLPIMLKSAIDPISQYTLDKLIEIGEDPKDPGGYFIVNGSERVIVTQEDLAPNRVLVDTGKTGSNITHTAKIISSTAGYRVPVTIERLKDGTFHVSFPAVPGKIPFVILMRALGILTDRDIVYAVSLDPEVQNELFPSLEQASSIANVDDALDFIGSRVAIGQKRENRIEKAQQIIDKYFLPHLGTSAEDRKKKAYYLAYAISKVIELYLGRREPDDKDHYANKRLRLAGDLFASLFRVAFKAFVKDLTYQLEKSKVRGRKLALKALVRPDIVTERIRHALATGNWVGGRTGVSQLLDRTNWLSMLSHLRRVISSLARGQPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALMAQIAVGINERIVEKTLYEMGVVPVEEVIRRVTEGGEDQNEYLKWSKVILNGRLIGYYQDGGELANKIRERRRKGEISDEVNVGHIVTDFINEVHVNCDSGRVRRPLIIVSNGNPLVTIEDIEKLESGAITFDDLVRQGKIEYLDAEEEENAYVALEPNDLTPDHTHLEIWSPAILGITASIIPYPEHNQSPRNTYQSAMAKQALGLYAANYQLRTDTRAHLLHYPQRPLVQTRALDIIGYTNRPAGNNAILAVMSFTGYNMEDSIIMNRSSVERGMYRSTFFRLYSTEEVKYPGGQEDKIVMPEAGVRGYKGKEYYRLLEDNGVVSPEVEVKGGDVLIGKVSPPRFLQEFKELSPEQAKRDTSIVTRHGEMGIVDLVLITETAEGNKLVKVRVRDLRIPTIGDKFASRHGQKGVIGMLIPQVDMPYTVKGVVPDIILNPHALPSRMTLGQIMEGIAGKYAALSGNIVDATPFYKTPIEQLQNEILRYGYLPDATEVVYDGRTGQKIKSRIYFGVVYYQKLHHMVADKLHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLLKDRLLDNSDRTMIYVCDQCGYIGWYDKNKNKYVCPIHGDKSNLFPVTVSYAFKLLIQELMSMIISPRLVLEDKVGLSGG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (Probable).  This subunit is involved in DNA promoter recognition (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo2, DNA-directed RNA polymerase subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_HELPH
Sequence: MLLVGRIGKSVGLNGGLKLHLESDFPECLKKGVKVSVAPINAFSRASSFKDYVIHSYEHAKNLLFLETIHTPEKAKELTNLGLFMSEAESKKLCVLKEGEFFYCDLVGLSVVEENEFLGKVIEIQRISQIDYFLVETTKSLVEKGLAKIFLIPYRDFYIQEILLQDKKITTHNAKTLLENS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBP_HHV11
Sequence: MPFVGGAESGDPLGAGRPIGDDECEQYTSSVSLARMLYGGDLAEWVPRVHPKTTIERQQHGPVTFPNASAPTARCVTVVRAPMGSGKTTALIRWLREAIHSPDTSVLVVSCRRSFTQTLATRFAESGLVDFVTYFSSTNYIMNDRPFHRLIVQVESLHRVGPNLLNNYDVLVLDEVMSTLGQLYSPTMQQLGRVDALMLRLLRICPRIIAMDATANAQLVDFLCGLRGEKNVHVVVGEYAMPGFSARRCLFLPRLGTELLQAALRPPGPPSGPSPDASPEARGATFFGELEARLGGGDNICIFSSTVSFAEIVARFCRQFTDRVLLLHSLTPLGDVTTWGQYRVVIYTTVVTVGLSFDPLHFDGMFAYVKPMNYGPDMVSVYQSLGRVRTLRKGELLIYMDGSGARSEPVFTPMLLNHVVSSCGQWPAQFSQVTNLLCRRFKGRCDASACDTSLGRGSRIYNKFRYKHYFERCTLACLSDSLNILHMLLTLNCIRVRFWGHDDTLTPKDFCLFLRGVHFDALRAQRDLRELRCRDPEASLPAQAAETEEVGLFVEKYLRSDVAPAEIVALMRNLNSLMGRTRFIYLALLEACLRVPMATRSSAIFRRIYDHYATGVIPTINVTGELELVALPPTLNVTPVWELLCLCSTMAARLHWDSAAGGSGRTFGPDDVLDLLTPHYDRYMQLVFELGHCNVTDGLLLSEEAVKRVADALSGCPPRGSVSETDHAVALFKIIWGELFGVQMAKSTQTFPGAGRVKNLTKQTIVGLLDAHHIDHSACRTHRQLYALLMAHKREFAGARFKLRVPAWGRCLRTHSSSANPNADIILEAALSELPTEAWPMMQGAVNFSTL
What is the function of this protein?
Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins.  In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication.
What are the official names of this protein?
Replication origin-binding protein, OBP, OriBP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae OriBP family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL3_XYLFT
Sequence: MGCYSMGFVGRKAGMSRVFLEDGCSIPVTLIEATANRVVQIKTSDVDGYDAVQVTVGSRRSVLVNKPESGHFAKAKVEAGRGLWEFRVEKTQLGSYSVGSEVGLSIFAVGQKVDIQGITKGKGFQGTIKRHNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVKQSVQNLEVIKIDVERCLIAVRGAIPGASGGDVLIRSASKI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DOSC_SHIBS
Sequence: MEMYFKRMKDEWTGLVEQADPLIRAKAAEIAVAHAHYLSIEFYRIVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIGIPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDSSASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFGLWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRVELWKASL
What is the function of this protein?
Globin-coupled heme-based oxygen sensor protein displaying diguanylate cyclase (DGC) activity in response to oxygen availability.  Thus, catalyzes the synthesis of cyclic diguanylate (c-di-GMP) via the condensation of 2 GTP molecules.  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (By similarity).
What are the official names of this protein?
Diguanylate cyclase DosC, DGC, Direct oxygen-sensing cyclase.
Protein: TIMP2_RAT
Sequence: MGAAARSLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
What are the official names of this protein?
Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP-2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_SHIDS
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SYNY3
Sequence: MPLQTFLFEIGTEELPADFVRSAITQWQGLIPPGLAAEFLQPESVEIYGTPRRLAVLIKGLPECQPDRLEEIKGPPASAAFKDGQPTPAALGFAKKQGVNPEDFEIRSTPKGDFIFVNKQLQGQASRDLLPKLALSWLKALDGRRFMRWGDGDWRFPRPIRWLVCLLDDQVLPLQIDNGSTTLVGDRLSRGHRILHPADVSLEHGQNYLAQLKTAGVVVDPQERRAMIEQQITTQAATLEGEAIIYEDLLDEVEQLVEYPTAVLGKFDQEFLSLPREVTTTVMVTHQRYFPVVDKDGRLLPHFITIANGDPSKGDIIAAGNGRVIRARLADAKFFYQADCDDSLDSYLPQLETVTFQEELGTMRDKVDRIMEMAAAIADQLGVTEQQRGEIDSTAMLCKADLVTQMVYEFPELQGIMGEKYALVSGESAAVAQGIVEHYLPRHQDDDLPQGLPGQVVGMADRLDTLVSIFGLGLLPTGSSDPFALRRAANAVINVAWAASLEINLLELLTQGCRDFVTSHPDKTSPLQALKTFFLQRLQTLLQDEQGIDYDLVNAVLGNGETNCDEAQSRLHDRLLADLQDVKERAQYLQELRDNGHLDAIYPTVNRSAKLASKGTLPTDQLDPRPVIQAPQLVQDSEKAVYQALLAIYPKAVEVQESRDYETLVNALHELAPTVAEFFDGPDSVLVMAENDELRQNRLNLLGLIRNYALILGDFGAIVKGI
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUZ12_MOUSE
Sequence: MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAASGGKSGGGGCGGGGSYSASSSSAAAAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTSIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQENKPGSVKPAQTIAVKETLTTELQTRKEKDNSNESRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESATPSNEEIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL
What is the function of this protein?
Polycomb group (PcG) protein.  Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene.  The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity).  Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.
What are the official names of this protein?
Polycomb protein Suz12, Suppressor of zeste 12 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to the inactive X chromosome in trophoblast stem cells.
Protein: TRPC_PYRAB
Sequence: MVIFGLSRRIKRCTKNPIIAELKVYSPKYGDLLRGRDPLEILRRYERAGAVGISYITDPKYFRGNFDFFKRLCKETELPVLRKDFITTKEEIEKTAEAGGSAVLLITRLLKDKLPEFVDHAREHGLDTLVEVHTLEELKIAIQTNSTMIGINNRDIGKLELDDGNVSLTAKLAPLIPDKFVKVSESGITTLEDLKVALKYADAALIGTALMKTEDPEKLLKSFVEAKIC
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: THIM_CHLT3
Sequence: MEINATTLWRDILAVRTKAPLVHNITNYVVMNSTANALLSIGASPVMAHAEEEVIDMVTIAGSLVINIGTLSKAWVAAMHKAMKKAHELQKPIVFDPVGAGATPYRTQTILELIHETPPSIIRGNSSEIKALVEAGIKTKGVDSTESSESAIEAAKHLSQKYGAVICISGATDHILNQEEYVRVENGHPMMTKVTGLGCTATAVVAAFAAINPSMMEATAHGMAAMGIAGEIAAKNVAGPGSLQVNFLDTLYSLSEADVHSHLKICA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CNTP5_CANLF
Sequence: MDSVPRLTGVFTLLLSGLWHLGSSATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNRRVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVMHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLDDSKPRLSSSPPSVTLGSLLDDQQWHSVLIERVGKQVNFSVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGTVRLVIQKMTERTAEILTGSSLNDGLWHSVSINARRDRITLSLDNDAASPAQDTTRVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGFCSQSWTTFYCNCSNTGYTGATCHNSLYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTHVRGANPEKPYTMALDYGGSMEQLEAMIDSSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNEKHPYWGGAPPGVQQCECGLDESCLDVRHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELIVHSPSLLNDNQWHYIRAERNLKETSLQVDSLPRMTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKLDLEERAKVTSGVRPGCPGHCSTYGSICHNGGKCVEKYSGYFCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYADAAPSKENIAFSFVTAQAPSLLLYINSSQDYLAVLLCKNGSLQVRYQLSKEETQVFNIDAENFANRRMHHLKINREGRELAIQVDHQLRLSYNFSSEVEFRAIRSLTLGKVREHLGLDSEIAKANTLGFVGCLSSVQYNQVAPLKAALRHATIAPVTVQGTLMESSCGSMVDVDVNTVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFSIIGIMTRFLYQHKQSHRTNQMKEKEYPENLDSSFRNDIDLQNTVSECKREYFI
What is the function of this protein?
May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
What are the official names of this protein?
Contactin-associated protein-like 5, Cell recognition molecule Caspr5.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS7_CAMJD
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIDIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIDKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: STLP2_ORYSJ
Sequence: MKRRHLPPVLVLLLLSILSLSFRRRLLVLQGPPSSSSSSRHPVGDPLLRRLAADDGAGSSQILAEAAALFANASISTFPSLGNHHRLLYLRMPYAFSPRAPPRPKTVARLRVPVDALPPDGKLLASFRASLGSFLAGRRRRGRGGNVAGVMRDLAGVLGRRYRTCAVVGNSGVLLGSGRGPQIDAHDLVIRLNNARVAGFAADVGVKTSLSFVNSNILHICAARNAITRAACGCHPYGGEVPMAMYVCQPAHLLDALICNATATPSSPFPLLVTDARLDALCARIAKYYSLRRFVSATGEPAANWTRRHDERYFHYSSGMQAVVMALGVCDEVSLFGFGKSPGAKHHYHTNQKKELDLHDYEAEYDFYGDLQARPAAVPFLDDAHGFTVPPVRLHW
What is the function of this protein?
Does not possess sialyltransferase-like activity in vitro.
What are the official names of this protein?
Sialyltransferase-like protein 2, OsSTLP2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: PURA_THEVB
Sequence: MANVVVVGAQWGDEGKGKITDLLSKSADVVVRYQGGVNAGHTIVVKDQTLKLHLIPSGILYPDTQCIIGAGTVVDPKVLLEELEQLEQLGVSTENLLIAETAHVTMPYHRQLDIAAEERRGSRRIGTTGRGIGPTYADKSERTGIRMLDLLDRDQLAAKLEWAIAQKNLILEKLYGLAPLEPQPIIEEYSAYGERLRSHIVDGSLVLDDAIRRRRNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACVGAGIGPTMIDRVIGVAKAYTTRVGEGPFPTELLDEVGELLGDRGAEFGTTTGRRRRCGWFDAVIGRYAVRINGLDCLAITKLDVLDELPEIKVCVAYDIDGERCEHFPSNALKFARCRPIYETLPGWQQSTRHCRSLDDLPKAALNYLKFLAEIMSVPIAIVSLGAERSQTIIVEDPIHGPKRALLKDDGTQVHPILS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABAH1_ORYSJ
Sequence: MGAFLLFVCVLAPFLLVCAVRGRRRQAGSSEAAACGLPLPPGSMGWPYVGETFQLYSSKNPNVFFNKKRNKYGPIFKTHILGCPCVMVSSPEAARFVLVTQAHLFKPTFPASKERMLGPQAIFFQQGDYHAHLRRIVSRAFSPESIRASVPAIEAIALRSLHSWDGQFVNTFQEMKTYALNVALLSIFGEEEMRYIEELKQCYLTLEKGYNSMPVNLPGTLFHKAMKARKRLGAIVAHIISARRERQRGNDLLGSFVDGREALTDAQIADNVIGVIFAARDTTASVLTWMVKFLGDHPAVLKAVTEEQLQIAKEKEASGEPLSWADTRRMKMTSRVIQETMRVASILSFTFREAVEDVEYQGYLIPKGWKVLPLFRNIHHNPDHFPCPEKFDPSRFEVAPKPNTFMPFGNGTHSCPGNELAKLEMLVLFHHLATKYRWSTSKSESGVQFGPFALPLNGLPMSFTRKNTEQE
What is the function of this protein?
Involved in the oxidative degradation of abscisic acid.
What are the official names of this protein?
Abscisic acid 8'-hydroxylase 1, ABA 8'-hydroxylase 1, Cytochrome P450 707A5, OsABA8ox1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS4_METEP
Sequence: MSKRVQAKHKLDRRMGQNIWGRPKSPVNRREYGPGQHGQRRKGKMSDFGTQLRAKQKLKGYYGNITEKQFRRYYAEAIRLRGDSGENLIGLLERRLDAVVYRSKFVATPFAARQFVNHGHIKVNGRRVNIPSYQVKAGDVIEVKEASRQLEIVVVASQLAERDVPDYIEVDHHKMTARVTRIPGLTEVPYPVQMEPNLVIEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS2_STRAW
Sequence: MAVVTMRELLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLLQSLSYIDRAYEFVKETVAHGGTVMFVGTKKQAQEAIAEQATRVGMPYVNQRWLGGMLTNFSTVYKRLQRLKELEQIDFEDVAASGLTKKELLVLSREKAKLEKTLGGIREMQKVPSAVWIVDTKKEHIAVGEARKLNIPVVAILDTNCDPDEVDYKIPGNDDAIRSVTLLTRVIADAVAEGLIARSGAGKAEGDKAAGEPLAAWERDLLEGEKKADEAEAPAAAEAEKPAEAAAEAPAAEAPAAEAPAAEAPAAEAPAADAEQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: KFA_CANAL
Sequence: MEDISEEQEFKYGEHSLQKIKVFKYSSTNASTYIYIHGGAWRDPSNTFDEMRPVLGIPNANLIGINYRLSPEIKHPEHLIDILRALRFVKQNFDVSQITLLGHSVGATMILQLLHYRQIIRDGLKHTHKDDLSSLDNLFAYVNDNVLLSQVIFLDGIYDVVELLKEYPDYASFVDDAFVSNKHFADSTQLSSANESLDLPFSLVSKDTKFLIYQSLEDDLLSMKQTHLLIDYLSSKNQGFTLHVGNWGKHEEIFGKYREIVFSGNVP
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.  Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H).  Required for elimination of toxic metabolites.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the kynurenine formamidase family.