PharMolix/UniProtQA huggingface dataset:
Protein: SYA_STAAC
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAISGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STAAC
Sequence: MTILSEIVKYKQSLLQNGYYQDKLNTLKSVKIQNKKSFINAIEKEPKLAIIAEIKSKSPTVNDLPERDLSQQISDYDQYGANAVSILTDEKYFSGSFERLQALTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEVLVEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKTNHYYISESGIHDASDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKVKS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: 4BD_HETMG
Sequence: GNCKCDDEGPNVRTAPLTGYVDLGYCNEGWEKCASYYSPIAECCRKKK
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction (PubMed:2412579).  Its toxicity is greater than that of RpII (AC P01534) (PubMed:2412579).
What are the official names of this protein?
Delta-stichotoxin-Hmg4b, Delta-SHTX-Hmg4b, Delta-stichotoxin-Rpa1b, Delta-SHTX-Rpa1b, RpIII, Toxin III.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
Protein: GBRB_MUSDO
Sequence: MSDSMLYQTLQTCLPKSRLITLWLAFTLAMLIQEPRRHAATVNAATAGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAVEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMTIQKMAEQKKQQQLDGVQPPPNPNPNTMVDHGGHGHGHGHHSHGHPHVPKQTVSNRPIGFQTMQQQNIGGRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPPVGPHGPGPQGPPGGPPAGGGGGGAPPEGGDAEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEEK
What is the function of this protein?
GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit beta, GABA(A) receptor subunit beta, MdRdl.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: VP4_ROTBB
Sequence: MRSLIYRQLLYNSYSVDLSDEITNIGAEKKENVTVQLGEFAQSQYAPVSWGSGETLSGNVEEQTLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSVTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYIKTSSTQAYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSNPVPNAVINLNADFYVIPDSQQETCTEYIRGGLPAMQTTTYVTPISYAIRSQRIARPNEDIIISKASLWKEVQYNRDIVIRFVFANNIIKAGGLGYKWSEISYKANNYQYTYMRDGVEVVAHTTVSVNGVSVYNYNTGPLPTDFMIRNYDVLKESSFVYVDYWDDSQAFRNMVYVRSLNAELNQVRCEGGHYSFALPVGSWPVMQGGSVILTFDGVTLSTQFTDYVSLNSLRFRFRCAVSEPSFRVTGTRISNLYGLPAANPMGDQQYYEAAGRFSLILLVPSNDDYQTPIANSVTVRQDLERQLDEMRREFNELSANIALSQLIDLALLPLDMFSMFSGIQSTVEAAKTFATSVMKKFRKSDLAKSVNSLTDAITDAAGSISRSSTLRSVNSAASVWTDISDIVDSTDNVVAATATAAAKKFRVKEFTTEFNGVSFDDISAAVVKTKMSKLNVVDEEILPQIITEASEKFIPNRAYRLIDGEKVYEVTTEGKYFAYLTETFEEVVFDAERFAELVTDSPVISAIIDFKTIKNLNDNYGITREQALNMLRSDPKVLRSFINQNNPIIKNRIEQLILQCRI
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: BAMD_ECO57
Sequence: MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQDGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTHPNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYTTDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLMENAYRQMQMNAQAEKVAKIIAANSSNT
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamA, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamD.
What is the protein family that this protein belongs to?
Belongs to the BamD family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RPOH_ECOLI
Sequence: MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARELGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of expression of heat shock genes.  Intracellular concentration of free RpoH protein increases in response to heat shock, which causes association with RNA polymerase (RNAP) and initiation of transcription of heat shock genes, including numerous global transcriptional regulators and genes involved in maintaining membrane functionality and homeostasis.  RpoH is then quickly degraded, leading to a decrease in the rate of synthesis of heat shock proteins and shut-off of the heat shock response.
What are the official names of this protein?
RNA polymerase sigma factor RpoH, Heat shock regulatory protein F33.4, RNA polymerase sigma-32 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SINA2_ARATH
Sequence: MAPGGSALKEVMESNSTGMDYEVKTAKVEVNNNKPTKPGSAGIGKYGIHSNNGVYELLECPVCTNLMYPPIHQCPNGHTLCSNCKLRVQNTCPTCRYELGNIRCLALEKVAESLEVPCRYQNLGCHDIFPYYSKLKHEQHCRFRPYTCPYAGSECSVTGDIPTLVVHLKDDHKVDMHDGCTFNHRYVKSNPHEVENATWMLTVFNCFGRQFCLHFEAFQLGMAPVYMAFLRFMGDENEAKKFSYSLEVGAHGRKLTWQGIPRSIRDSHRKVRDSQDGLIIPRNLALYFSGGDRQELKLRVTGRIWKEE
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:28351989, PubMed:32786047).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:28351989, PubMed:32786047).  It probably triggers the ubiquitin-mediated degradation of different substrates (PubMed:28351989, PubMed:32786047).  Mediates the proteasomal-dependent degradation of ATG6, a component of the autophagosome complex (PubMed:28351989).  Requires TRAF1A/MUSE14 and TRAF1B/MUSE13 to target ATG6 for ubiquitination and subsequent regulation of autophagosome assembly (PubMed:28351989).  Modulates directly the ubiquitination and proteasomal-dependent degradation of FREE1, a component of the ESCRT-I complex (PubMed:32786047, PubMed:32753431).  Modulates directly the ubiquitination and proteasomal-dependent degradation of ELC/VPS23A, a component of the ESCRT-I complex (PubMed:32753431).
What are the official names of this protein?
E3 ubiquitin-protein ligase SINAT2, RING-type E3 ubiquitin transferase SINAT2, Seven in absentia homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Endosome, multivesicular body. Cytoplasmic vesicle, autophagosome.
Protein: CITD_STRPD
Sequence: MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNHIRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_BURO1
Sequence: MSKTHFGFESVEENEKAKKVAGVFHSVASNYDLMNDLMSAGMHRAWKAFTIAQANVRPGFKVLDIAAGTGDLTKSFAKAAGPTGEVWHTDINESMLRVGRDRLLDKGIVTPSLLCDAEKIPFPDNYFDVVTVAFGLRNMTHKDAALAEMRRVTKPGGRVMVLEFSKVWDPLKKAYDLYSFKVLPWLGDKFAKDAESYRYLAESIRMHPDQDTLKTMMEQAGLDAVKYYNLSGGVVALHLGTKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ITRY1_BAURF
Sequence: SVVLDTKGQPVRNAADAYYLEPVARGDGGLALAKVGNEAEPKAVVLDPNHRPGLTVRFETPLRINIIKESFFLNIKFVPSSSESEVWEVRQQYPEGLAVKVTDTKSLVGPFRVEKEGEGYKIVYYPDRGETGLDIGLVHRNEKYYLAVKDGEPFVFKIRKATDE
What is the function of this protein?
Inhibitor of trypsin and human plasma kallikrein with a Ki of 2. 9 nM and 14. 0 nM, respectively.  Does not inhibit chymotrypsin, porcine pancreatic elastas, human neutrophil elastase, coagulation factor Xa, human thrombin, porcine pancreatic kallikrein or plasmin.
What are the official names of this protein?
Kunitz-type trypsin inhibitor BrTI.
What is the protein family that this protein belongs to?
Belongs to the leguminous Kunitz-type inhibitor family.
Protein: SYS_KOSOT
Sequence: MIDIRLVRENPEKIRAALKNRCVDESILDELLELDKARREAISTSDRKKAERNKISSQIAKAKASGDEALAKELMEKAKDISVEVKELSEKAKKLDEEMRNKLLYIPNIPHESVPVGESEEDNVVVRKWGEPRQFDFDSLAHWDLGPNLGMMDFERAAKLSGSRFVILRKELARLERALINFMLDLHTREHGYEEVALPHLVKRETMQATGQLPKFEEEAYKTDPDDMFLIPTAEVPLVAQHRDEILNLNELPRKYTAYTPCYRREAGSYGKDVKGMIRVHQFDKVELVWFVHPDESYEALEKLTADAEEVLKRLGLPYRVVALCTGDLGFAAAKTYDIEVWLPSYNAYKEISSCSNVEDFQARRGNMRFRDKDNKLKYVHTLNGSGLAVGRTLVAIVENYQLPDGRIRVPEVLVPYMGTEVIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL06_ARATH
Sequence: MEKTFALITIFLAFAFSGKCSDVFSRCDFPEGFVFGSSTSAYQWEGAVAEDGRKPSVWDRFCHSHNNQGNGDITCDGYHKYKEDVKLMVDTNLDAFRFSISWSRLIPNRRGPVNQKGLQFYKNLIQELVNHGIEPYVTLHHFDHPQYLEDEYEGWLNHMIVEDFTAYADVCFREFGNHVKFWTTINEGNIFSIGGYNDGDSPPGRCSIPGQNCLLGNSSTEPYIVGHNLLLAHASVSRLYKQNYKDKQGGSIGFSILTIGFSPSTSSKDDAIATQRANDFFNGWMLGPLIYGDYPDTMKRIVGSRMPVFSEEESEQVKGSSDYIGINHYLAASITNSKLKPSISGNPDFYSDMNVILSFFANFSSSEYDVAPWAIEAVL
What are the official names of this protein?
Putative beta-glucosidase 6, AtBGLU6.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: NADK_OLEA2
Sequence: MHRELKRVFIVTKQAHAGAAALAADMQAWFAARGIEAATEENDTASALPDFARSASCIMVLGGDGTMLSVSRRAVGLDVPLLGVNLGKVGFLAEVSAAGWQQAFTRLAENGLTCSERLALHFAVSREGRCVFEGTAVNDVVLHRGVLARVINLGLGVDGEWLGDLRADGLIVSTPTGATGYAVSAGGPLVHPDMSVYAITPICPFLNNFHPMVLAGSMRFEIRILEGPQEVYVTQDGQECFALQAGDLVTVTQASRGLLFVAVEGSTYFTRLRAKGFVRDPRGRGRAVPASS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S8H_ARATH
Sequence: MGINFEDQTTLFNFVVREGNGVKGMIDSGLSSVPRPFVQPLSERIPTQKALTCEATQPIDLSNLDGPQHKEVAKQIVEAAETLGFFQVVNHGVSVELLELLKSSAHEFFAQAPEEKSMYLKEVSPSKLVKYGTSFVPDKEKAIEWKDYVSMLYTNDSEALQHWPQPCREVALEFLNSSMEMVKNVVNILMENVGVTLEEEKMNGLMGTKMVNMNYYPTCPSPELTVGVGRHSDMGMLTVLLQDGIGGLYVKLDNGEWAEIPPVHGALVINIGDTLQILSNGKYKSAEHRVRTTNIGSRVSVPIFTAPNPSQKVGPLPEVVKRDGVARYKEFLFQDYMNNFFGQPHDGKKSLDFARAE
What is the function of this protein?
Involved in the pathway of sideretin biosynthesis from feruloyl CoA, a redox-active catecholic metabolite exuded by roots in response to iron deficiency in order to facilitate the uptake of iron; this pathway consists in the successive conversion from feruloyl CoA to scopoletin, from scopoletin to fraxetin and from fraxetin to sideretin.  Catalyzes the biosynthesis of fraxetin via scopoletin hydroxylation.
What are the official names of this protein?
Scopoletin 8-hydroxylase, 2-oxoglutarate-dependent dioxygenase S8H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: TRUA_MYCGE
Sequence: MARYLGIVSYDGSYFKGWAIQPNLATIQGLLEQSFSLIIGRKIKVIGSGRTDKGVHAINQTFHVDINGEINLNLLIRKINQLIKPHCIVKTLVLVNDSFHARFQVKTKVYEYLINCGNLNPLQFNYVWQLNQQLDLEKLKADATLFLGKKNFLSFSSSIHTDSIRTISKITIQKETNQLVRLTFFGSGFLRSQVRMIVACLVNLNTNKMALETVAKLFEHPKKGSCVVKAPSCGLYLKTVVYEK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NDK_LAWIP
Sequence: MQHTFALIKPDAVQRNLIGAIINMIEKNDFYISAMKMLQMNRQQAEGFYSVHRERPFFNELVDYMISGPIVSLILTGENAVTRYRELMGATNPQNAQEGTIRKSFAISLMENAVHGSDSDENAIIEINYFFNAFERIR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV61
Sequence: MRMESLADRLDACQEKLLDLYEKDSNKLEDQILHWHYVRLENAMLFKARQAGLTRVGHQMVPTLSVTKGKAHKAIEVHLSLQGLQTSAYAHEPWTLQTTSLEMWNTQPQRCWKKKGRRLTVKFDGEDHKAVEYVSWGYIYVQSTETDLWYKVPGKVSYKGLYYEMEGQEHYYVTFAQEAQKYGETGKWEVHMGNTVIYEPCASVSSTQDAVREVSTAETAGHLRDNTTQTTTTPTCVGPTQTSTSVQTPPHKRQRLHRDREQQPDTTQKDNHKRVDSTDQWINGHRNSTETGDNCDSYSSPVIHLKGDPNKLKCFRYRLQHSVPELFDKASSTWHWAGGQSTTRAAFVTLWYVNVEQRKQFLNRVTIPKGIQATAGYMSMCI
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MINE_FRAP2
Sequence: MLAKLFGLGKKQQSASLAKERLQIIVAHQRNELHPRSSKISSHLLAELKDEIIEVVKKYVALSEDNIRDIDIKVEDSSKNSTIEVNIPFN
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PSBN_SYNSC
Sequence: METSSPALSVAIGVLAVLFGLTGFGVYQAFGPPSKALDDPFDDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SUT1_STYHA
Sequence: MSQRVSDQVMADVIAETRSNSSSHRHGGGGGGDDTTSLPYMHKVGTPPKQTLFQEIKHSFNETFFPDKPFGKFKDQSGFRKLELGLQYIFPILEWGRHYDLKKFRGDFIAGLTIASLCIPQDLAYAKLANLDPWYGLYSSFVAPLVYAFMGTSRDIAIGPVAVVSLLLGTLLSNEISNTKSHDYLRLAFTATFFAGVTQMLLGVCRLGFLIDFLSHAAIVGFMAGAAITIGLQQLKGLLGISNNNFTKKTDIISVMRSVWTHVHHGWNWETILIGLSFLIFLLITKYIAKKNKKLFWVSAISPMISVIVSTFFVYITRADKRGVSIVKHIKSGVNPSSANEIFFHGKYLGAGVRVGVVAGLVALTEAIAIGRTFAAMKDYALDGNKEMVAMGTMNIVGSLSSCYVTTGSFSRSAVNYMAGCKTAVSNIVMSIVVLLTLLVITPLFKYTPNAVLASIIIAAVVNLVNIEAMVLLWKIDKFDFVACMGAFFGVIFKSVEIGLLIAVAISFAKILLQVTRPRTAVLGKLPGTSVYRNIQQYPKAAQIPGMLIIRVDSAIYFSNSNYIKERILRWLIDEGAQRTESELPEIQHLITEMSPVPDIDTSGIHAFEELYKTLQKREVQLILANPGPVVIEKLHASKLTELIGEDKIFLTVADAVATYGPKTAAF
What is the function of this protein?
High-affinity H(+)/sulfate cotransporter that mediates the uptake of sulfate by plant roots from low concentrations of sulfate in the soil solution.
What are the official names of this protein?
High affinity sulfate transporter 1.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1820_STAAW
Sequence: MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
What are the official names of this protein?
UPF0435 protein MW1820.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: RL7_BACSU
Sequence: MALNIEEIIASVKEATVLELNDLVKAIEEEFGVTAAAPVAVAGGAAAGGAAEEQSEFDLILAGAGSQKIKVIKVVREITGLGLKEAKELVDNTPKPLKEGIAKEEAEELKAKLEEVGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12, BL9, Vegetative protein 341, VEG341.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y024_LISIN
Sequence: MGLTFFDKARELTEELEKTQAENIHQAAKLVAESIMNEGIIQAFGSGHSYAAAIEVCGRAGGLIPSKVIMDPAGGYYESIEGVGSLLTHRLQAKPNDIFFLISNSGRNPMGIELAEWIKAQGCKLIVVTALDASQTAASRHSSGKLLYEFADVILDNRSVQGDAALELDGLEGKVCGTSSFSAVLLLQQTIYEAVELMLEKGYTPPVYRSANIDGGYEYNFAIEDKFADRIFHL
What are the official names of this protein?
UPF0309 protein lin0024.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: KTHY_MYCS5
Sequence: MFITFEGLDGSGKTTVINELLKKLKDNFKFLDYVLTREPGGKDIKESEKIREMILDSDLEFSPITEALLYTTSRRIHIDKVILPALAQNKIVFCDRYYDSFYAYQGYGRNLGMEFTKTLTELAVGKTIPNLTFFFDISPFETRKRRSENNLINDRLELEDLSFHNRVYEGYLEIIKNNKENRFVVVDATKPVNEIVDFIFNYLVKHKDFVKFLK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PLSY_ALIFM
Sequence: MTPLALIMIIIAYLLGSISSAVLICRLKGLPDPRTSGSHNPGATNVFRIGGRSAAGLVLLCDILKGMLPVWGGYFLEINPFMLGIIAISACLGHMYPLFFHFKGGKGVATALGALAPIGLDLTGMLFGCWVVTVLVTGYSSLASMITALLAPLFTWLVKPQYTLPVAMLSCLIVLKHHENIKRFFEGKETKIWQRKRD
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURI_CLOAB
Sequence: MSVKNNPIGVIDSGVGGISVLKEAVKQLPYENFIYYGDSKNAPYGIKSVDEVRNLTFNVVEKLLKLNIKALVVACNTATSAAIDELREKYKNIPVIGIEPALKPAVELKRRGKIIIMATPMTLSEVKFKNLMEKYEKDSEIVKLPCPGLVELIEDGIVEGEKMQEYLRNKFKDYEKDDIAAFVLGCTHYPFVKKEIASIARDVPIIDGSQGTVMQLKRKLDKYDILNIGSEKGKIKIMNSLKDDKILDLSHRLLDL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.