PharMolix/UniProtQA huggingface dataset:
Protein: P2RY8_CHICK
Sequence: MVKNGSHLDAETLAMLQNKAISITLPVVYTMVAIISIPGNFFSLWVLCWHIKPKTPSVIFMINLSITDLLLACCFPFQIFYHIQRNHWIFGKTLCSLVTVMFYSNMYSSILTMTCISIERYMGVVYPMKLIKWRRKRYALGACVIMWIFLLLAFYPLESTDLTYEVKELGIITCFDVLKWEMLPNFAAWVAFLLTLFVVLFLIPFIVTVGCYIGTIRKLIQTSSRYGNKQKTRSIYLAIIVLSVFITCFAPNNFILLAHMIVRLFYEGSLYPAYKLTLCLSCLNNCIDPFIYYFASKEFYQKFMQVFRPKVPLSDSLETRRESLFSGRTMSVRSMSSGPMDGLEGVKICLQRQESVF
What is the function of this protein?
Probable receptor for purines coupled to G-proteins.
What are the official names of this protein?
P2Y purinoceptor 8, P2Y8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LZTL1_RAT
Sequence: MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAHTNVLLLRQLFSQAEKWYLKLQTDVSELENRELLEQVAEFEKAEFASSNKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIETQAVNALDEKSKLERVLQDLQLDQGNQQDFIKAQDLDDLENTVAALKSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED
What is the function of this protein?
Regulates ciliary localization of the BBSome complex.  Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.  May play a role in neurite outgrowth.  May have tumor suppressor function (By similarity).
What are the official names of this protein?
Leucine zipper transcription factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the LZTFL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHU2_YEASO
Sequence: MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLXYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPXILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKICCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_ACIAD
Sequence: MALTNEEILNAVAEKTVLELVELISAFEEKFNVSAAAVAVAAGPAAAAVEEQTEFNVELTSFGANKVAVIKAVREATGLGLKEAKDLVEGAPQVLKEGISKEEGEELKKKLEEAGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FADB_VIBCH
Sequence: MIYQAKTLQVKQLANGIAELSFCAPASVNKLDLHTLESLDKALDALAADSSVKGLLLSSDKEAFIVGADITEFLGLFAKPEAELDEWLQFANRIFNKLEDLPFPTLSALKGHTLGGGCECVLATDFRIGDATTSIGLPETKLGIMPGFGGTVRLPRLIGADSAMEIITQGKACRAEEALKVGLLDAIVDSDKLIDSAITTLTQAIEEKLDWQKRRQQKTSALTLSKLEAMMSFTMAKGMVAQVAGKHYPAPMTSVVTIEEAARLPRDAALDIERKHFIKLAKSTEAQALVGIFLNDQYIKGLAKQSAKAASQDTQHAAVLGAGIMGGGIAYQSALKGVPVLMKDIAPHSLELGMTEAAKLLNKQLERGKIDGFKMAGILASITPSLHYAGIDQADVIVEAVVENPKVKAAVLSEVEGLVDTETILTSNTSTIPINLLAKSLKRPQNFCGMHFFNPVHRMPLVEIIRGEHTSEDTINRVVAYAAKMGKSPIVVNDCPGFFVNRVLFPYFAGFSLLMRDGANFTEIDKVMERQFGWPMGPAYLLDVVGIDTAHHAQAVMAEGFPTRMAKSGREAIDALYEAKKFGQKNGSGFYQYTVDKKGKPKKAFSDDVLAILAPVCGAPQSFDPQTLIERTMIPMINEVVLCLEEGIIASAQEADMALVYGLGFPPFRGGVFRYLDTIGIANYVAMAEKYADLGALYQVPQLLKNMAQQGTSFYSAQQVSAL
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: AROB_ERWT9
Sequence: MERITVTLGERSYPITIAAGLFSDPTSFWPLKAGEQAMLVTNQTLAPLYLDTLCARLEGAGVIVDRVILPDGEQYKTLAVMDQVFSALLAKPHGRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPAAVVVDLDCLDTLPARELSSGLAEVIKYGIILDGDFFSWLEKNLDALLALDGTAMSRCIRRCCELKAEVVAADEHEHGLRALLNLGHTYGHAIEAHMGYGNWLHGEAVAAGMVMAARTAERLGQFNPQDTDRIISLLQRAGLPVKGPESMTAEEYLPHMMRDKKVLAGEMRLVLPLEIGRAELRRGVAHDIVLASIRDCQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECM_YERPN
Sequence: MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRLSFSVDYWQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: BPTA_BORBN
Sequence: MREILFFGLLSICIFLVFFFYKQKENNIIYNRIVEKFEDNVVIDEIYTHLFKDSNLKELVFIKSQLIIPELEHKKMIKATGYRADAYKALSTVYRFDFKVHDNKILGFKSVIFEGFEDAKVSKHENNLPSEKWQQLKDFNIGDPNINEKFFHLEFPFVVKNTLCVTISKGFFKKIKKLKRLKIMLISNEDREYKIDIENFLPKYNL
What is the function of this protein?
Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the Lyme disease spirochete.
What are the official names of this protein?
Protein BptA, Borrelial persistence in ticks protein A.
What is the protein family that this protein belongs to?
Belongs to the BptA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CRCB2_CORDI
Sequence: MIPALFLAAALGGMLRFLLSKIGPYVGTFIANMAACVVLAAVRDASPLVMAAVGTGFAGALSTWSTLAKELGTLIRQRRWAMLLGYTTATILGGMVAVWCGLQI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRCB2_DEIGD
Sequence: MPFWFGVAVGGALGALARYGVSLLVAGRLASTAWGNFPLATLLVNVLGSFLLAFITTLALRGLVSPAWRLAVGTGFIGALTTFSTFAWESDLMVRDGEAARASLYVLGNLVLGYAAVLLGRALAARLGGGA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLPX_MYCTO
Sequence: MTAEGSGSSTAAVASHDPSHTRPSRREAPDRNLAMELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDSSAVYPLP
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.  Seems to be the major FBPase of M. tuberculosis and to play a key role in gluconeogenesis for conversion of lipid carbon into cell wall glycans.  Does not display activity against inositol 1-phosphate (By similarity).
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRT1_SEPOF
Sequence: MKVAANSSKMLAEKLELMKGGRRRRRRSRRRRRRSRRRSRSPYRRRYRRRRRRRRRRSRRRRYRRRRSYSRRRYRRRR
What is the function of this protein?
Cuttlefish spermiogenesis is characterized by a double nuclear protein transition: histones -> spermatid-specific proteins (T1/T2) -> protamines (SP1/SP2).  The protamines compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Spermatid-specific protein T1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: COX13_SCHPO
Sequence: MSMMNRNIGFLSRTLKTSVPKRAGLLSFRAYSNEAKVNWLEEVQAEEEHAKRSSEFWKKVTYYIGGPALILASANAYYIYCKHQEHAKHVEDTDPGYSFENLRFKKYPWGDGSKTLFWNDKVNHLKKDDE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 13, mitochondrial, Cytochrome c oxidase polypeptide VIa.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MURB_BUCAI
Sequence: MHKKKYFSSQSLKDLNTFAIDVTAKKIIFVKTIQSLIDISKICQLSNIPYIILGEGSNVLFLENYVGVVIINRIKGIKIVEKKNFWLLHVFSGEKWHNLVKLTLNLGILGLENLALIPGCIGSAAIQNIGAYGLEFKDVCQYVDILSLKDNTIKRIYKNSCKFSYRNSIFKDQYKNEHAVIRVGIKLSKKWRPILFSSLENYITPINITAYKIFNIICKIRKKKLPDPKKIGNAGSFFKNPLIKKKKAQKLINLYKVPNYPQKNGLVKISAAWLIENYKFKHLQIGDAAIHKKQKLILINKKNATAQEIIKLAKIIHKCILKKFNILLEPEVDLIGASGKIKASKIFKLNSKLKVI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_SULID
Sequence: MEELPATAIGLKVNDGIVLASERRLSYGGYVLSKQAKKVHKIGKFLMAGAGIYGDLQTLTRIMNVEIKYYEISTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMNLDIAAQLITKAIKASIERDITSGDGIDLAIMDKKGNYENKFIPY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_GEOSW
Sequence: MSKRIKCTLSYDGTHFFGYQIQPGKRTVQGELERVLEQMHKGKAIRVTASGRTDAGVHAYGQVIHFDTFLSLSPDQWKKALNAQLPDDIVIKDVQEADPSFHARFSAKAKEYRYKVRIAQERDVFLRNYCYHYPYPLDMEAMRHALRLIEGTHDFTSFCSAKTDVDDRVRTIYKADMAMHDDLLEFCFIGNGFLYNMVRIIVGTILEVGQGKRSIDSISHAFEAKDRQFAGKTAPPQGLYLWKVYYDN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: SYV_XANOM
Sequence: MTTLASSYDPSSFESRLYAQWEAAGYFVPSDTGEPYTVLLPPPNVTGTLHMGHAFQQTLMDALVRYHRMRGYDTLWQVGTDHAGIATEMVVSRNLALEGKGETRDSLGREGFIAKVWEWNAASGDTIERQMRRLGTSSDWSRSTFTMDPQPSAAVNEAFVRWYEQGLIYRGQRLVNWDPVLKTAISDLEVENVEEDGFLWSIRYPLADGVTYEHIEHDADGNETLRETRDYLVVATTRPETMLGDTAVMVHPEDARYLTLHTARIVLPLTGRHVPVITDDYVDRAFGTGVVKVTPAHDFNDYQVGERHNLPLVNLFTADAKIIDPRKQYPDDESPFVNAGIDWRELDQIQRKRLGQHLAYKIPAQYIGLDRYDARKLVLSELEDLSILVETKPHKLQVPRGDRTGQVIEPYLTDQWFVKMDALAKRGLELVESGQIQFVPPNWINTYRHWMENIQDWCISRQLWWGHRIPAWFDDAGHCHVGHDEAEVRAKHGLGAEIALHQDSDVLETWFSSQLWPFSTLGWPDSQAMAERGFARYLPSSVLVTGFDIIFFWVARMIMATDSFTGQVPFRDVYITGLIRDAQGQKMSKSKGNVLDPLDIIDGISIEDLVAKRTNGLMQPRMAEKIEKATRKEFPDGIIAHGADALRFTIAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFVLMNTEGARFTGVPQPRTEAEKWILARLDKVTAETHAHYANYRFDLLAQSLYEFAWNAFCDWFVELAKPALNNQDTDAAASTRHTLLYVLESLLRLLHPLTPFVTEELWQQVVPRLGITTATISLQRFPQVGDVDTSGYATAEADVEWLKSMVSALRRVRSELNVPPSKQVRLLLQADTADERPRVARFASQLSFLLKLERIDWLDAGQDTPPSAAAIVGELTLLVPLEGLVDMDAERMRLDKEIKRVKGEIGKCNGKLGNATFVQNAPAVVVDQERARLADWTTQLAGLREQRGKL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_STRPQ
Sequence: MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDKDRFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYHQIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRVDVELMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALFC1_PEA
Sequence: GLTIRAGSYADELVKTAKTIASPGRGILAMDESNATCGKRLASIGLENTEVNRQAWRTLLVTVPTLGEYISGAILFEETLYQSTTDGRKIVDVLIEQNIIPGIKVDKGLVPLAGSNDESWCQGLDGLASRSAAYYQQGARFAKWRTVVSIPNGPSALAVKEAAWGLARYAAISQDNGLVPIVEPEILLDGEHGIDRTFEVAQKVWAEVFYYLAENNVQFEGILLKPSMVTPGAESKDKASPTKVAEYTLNLLHRRIPPAVPGIMFLSGGQSEVEATLNLNAMNKSPNPWHVSFSYARALQNTALKTWGGLPENVKAAQEALLFRAKSNSLAQLGKYYGDGESEEAKKELFVKGYSY
What are the official names of this protein?
Fructose-bisphosphate aldolase 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HBA_XENTR
Sequence: MHLTADDKKHIKAIWPSVAAHGDKYGGEALHRMFMCAPKTKTYFPDFDFSEHSKHILAHGKKVSDALNEACNHLDNIAGCLSKLSDLHAYDLRVDPGNFPLLAHQILVVVAIHFPKQFDPATHKALDKFLVSVSNVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ENDA_HALS3
Sequence: MDGDLRGDTVHIGGDARQRFHDARGYGYPLGGNDIAVSLVEAAHLLFRGDLDSVDGMGFRAFLTDREAGFAARFLVYVDLRDRGFYLVPDRDPWWRDPGDGDFVVFPRGNTRRDGVVKHRVRVVDERTTLPVDGLSESVLAVVDEESEITYLDIAPETPTGETTLDRPTDVPGVLLDDRVLVWEPPQRLHNAGFYGQPLGGRAADHDALQLSLVEAAYLIDAGVLRLTDATIDDVRARGRLGEGEHFDCRLAVYRALRDAGAVPKTGFKFGADFRVYSAVSSVDDLGHSELLVRVITDTHVFSPGDLSLDVRLAHGVRKRMVFAATDDTDDTIRWLSVSRLTP
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
Protein: TIG_GLOVI
Sequence: MKVTQEKLPRSQMGLNVEVEGEKSKQAYEKLVRDTMRTARIPGFRPGKAPRQLVLQFYGKERLRAQALENLIDSSLKEAIEQESIASLGNLQLRDSFEELLGRYQPGEPLSFKAAVDVQPEVQLGTYTGLTVRYSEVPYEAKQVDDQLEQYREQRAVLVPVEGRAAEVGDTAVIDFAGTKAADGNEIVGGKATDFEVELLPGRLIAGFTEGIIGMQIGESTELALRFPDDYPQQELAGVDAKFAVSLKDLKIKELPVLDDDFAGDISEFETLEALRAFLEQQQQEQAAEKTRANRDAAIIKALVAETTVDLPETLVNREVQFLAEQSFRNLQQQGIDPSRIFTEENMPRVRETLRVDAENRLKRTLALAQVARAENIVVEEEQVAARIVELRSELEEEVSEQALAEFAREEMLTEKILEWLAEHSTIELTLPGEAIEPGSGEDAPPEVAAGATEPEAQPNS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CYSN_ECOSE
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIRKDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDHEEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFSHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: SUSC_BACTN
Sequence: MKKGNFMFKVLLMLIAGIFLSIDAFAQQITVKGIVKDTTGEPVIGANVVVKGTTTGTITDFDGNFQLSAKQGDIIVVSFIGYQPQELPVAAQMNVILKDDTEILDEVVVIGYGQVKKNDMTGSVMAIKPDELSKGITTNAQDMLSGKIAGVSVISNDGTPGGGAQIRIRGGSSLNASNDPLIVIDGLAIDNEGIKGMANGLSMVNPADIETLTVLKDASATAIYGSRASNGVIIITTKKGKNGQAPSVSYNGSVSFSKTQKRYDVLSGDEYRAYANQLWGDKLPADLGTANTDWQDQIFRTAVSTDHHVSINGGFKNLPYRVSLGYTDDNGIVKTSNFRRFTASVNLAPSFFEDHLKFNINAKFMNGKNRYADTGAAIGGALAIDPTRPVYSNEDPYQFTGGYWQNINSTTGFSNPDWKYTSNPNSPQNPLAALELKNDKANSNDFVGNVDVDYKFHFLPDLRLHASIGGEYAEGTQTTIVSPYSFGNNYYGWNGDVTQYKYNLSYNIYVQYIKSLGANDFDIMVGGEEQHFHRNGFEEGQGWDSYTQEPHDAKLREQTAYATRNTLVSYFGRLNYSLLNRYLFTFTMRWDGSSRFSKDNRWGTFPSLALGWKIKEENFLKDVNVLSDLKLRLGWGITGQQNIGDDFAYLPLYVVNNEYAQYPFGDTYYSTSRPKAFNENLKWEKTTTWNAGLDFGFLNGRITGGIDGYFRKTDDLLNSVKIPVGTNFNAQMTQNIGSLENYGMEFSINAKPIVTKDFTWDLSYNITWNHNEITKLTGGDDSDYYVEAGDKISRGNNTKVQAHKVGYAANSFYVYQQVYDENGKPIENMFVDRNGNGTIDSGDKYIYKKPAGDVLMGLTSKMQYKNFDFSFSLRASLNNYVYYDFLSNKANVSTSGLFSNNAYSNTSAEAVALGLSGQGDYMSDYFIHNASFLRCDNITLGYSFQNLWKTQTYKGVGGRVYATVQNPFIISKYKGLDPEVKSGIDANPYPRAMTFLLGLSLQF
What is the function of this protein?
Mediates transport of starch oligosaccharides from the surface of the outer membrane to the periplasm for subsequent degradation.
What are the official names of this protein?
TonB-dependent receptor SusC, Starch-utilization system protein C.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PLSY_PROM1
Sequence: MNLLILFFGYLFGSFPSGYLAGRIAKGIDIRSLGSGSTGATNVLRHIGKRAAIIVFLLDVFKGVLSILLAKYLLLNDSWQVAIGLSTLIGHIWPVWLNWKGGKAVATGLGIFLGLSWQVGLATLGVFIIMITLFRIVSLASVSASLALPLIMFLSFSGSNISLPFLIVSLLAMLLVIWRHRENIVRLIRGKEPRIGQP
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEFLU_LUCSE
Sequence: MKFFMVFAVTFCLALSFVSQSLALPADDEAHFVDGLEALKTIEPELHGRYKRATCDLLSGTGVKHSACAAHCLLRGNRGGYCNGRAICVCRN
What is the function of this protein?
Shows strong antibacterial activity against numerous Gram-positive bacteria.  It selectively inhibits peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:20508130).  Shows antibacterial activity against the Gram-positive bacteria M. luteus, E. fecalis (MIC=32 mg/L), S. aureus (MIC=16 mg/L), S. carnosus (MIC=2 mg/L), S. pneumoniae (MIC=2 mg/L) and S. pyogenes (MIC=2 mg/L) and against a number of methicillin-resistant S. aureus and glycopeptide-intermediate S. aureus isolates (PubMed:20542901, PubMed:19921400, PubMed:21560219).  Does not show antibacterial activity against Gram-negative bacteria or antifungal activity against C. utilis (PubMed:20542901).  Shows slight antifungal activity against C. albicans (PubMed:21560219).
What are the official names of this protein?
Defensin Lucifensin, Sericasin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: FOXI3_CANLF
Sequence: MALYCGDNFGVYSQPGLPPPAAAAAAAAAAPGAPPASRAPYALADYAAPPAAAANPYLWLNGPGVGVGVGVGVGGPPAAAAAAAAAYLGAPPPPPPPPGGAAGPFLQPPPAAGTFGCAQRAFAQPAPAAPASPAGPAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASSASTSTVAAGTTKSEEGLSSGLGSGVGGKPEGDSPSALLRPPQSPEPPEGTKSTASSPGGSLLSSAPCLNTFFSSLSTLSVSSSGGAQRAGPGSRHLGIQGTPLSSSGAFPASCISSEAPPDTLQLSNGASSGSGQRSSYYSPFPASTSGGQSSPFGSPFYNFSMVNSLIYPREGSEV
What is the function of this protein?
Possible transcriptional factor.  May play a role in the development of the epithelium of hair and whisker placodes and that of teeth.
What are the official names of this protein?
Forkhead box protein I3.
What are the subcellular locations of this protein?
Nucleus.