PharMolix/UniProtQA huggingface dataset:
Protein: CCSA_SOYBN
Sequence: MVFASLEHILTHISFSVVSILISIHLITLLFVKEIIGLSDSSKKGMIITFFCITGLLVTRWVFSGHLPFSDLYESLIFLSWTFSIFYMVPYFKKSKNYYLNTIITPSVIFTQGFATSGLLTKMHESLILVPALQSHWLMMHVSMMILGYATLLCGSLLSVAILVITFQELIQIIGKSKNFYFLNESFSFAEIKYMNMTDKNNVLQKTSFLSYRNYYRSQFLQQLDRWGYRTISLGFIFLTIGIISGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHTRKNKKLEDLNSSIVASIGFLIIWVCYLGINLLGIGLHSYGSFTPN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ALBA_METAR
Sequence: MPEDNVIFVGNKPVMNYVLAAVTQFNEGAKEVTIKARGRAISRAVDTAEVVRHRFLTDVEIDRIQISTEELASEKGEKINVSSIEIFLKRPRAATD
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
What are the official names of this protein?
DNA/RNA-binding protein Alba.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: SELT_RAT
Sequence: MRLLLLLLVAASAVVRSEASANLGGVPSKRLKMQYATGPLLKFQICVSUGYRRVFEEYMRVISQRYPDIRIEGENYLPQPIYRHIASFLSVFKLVLIGLIIVGKDPFAFFGMQAPSIWQWGQENKVYACMMVFFLSNMIENQCMSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILDNEMKLNVHMDSIPHHRS
What is the function of this protein?
Selenoprotein with thioredoxin reductase-like oxidoreductase activity (PubMed:26866473).  Protects dopaminergic neurons against oxidative stress and cell death (By similarity).  Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (PubMed:18198219).  Plays a role in fibroblast anchorage and redox regulation (By similarity).  In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (PubMed:26779623).  In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity).
What are the official names of this protein?
Thioredoxin reductase-like selenoprotein T, SelT.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein T subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: 3S1CB_NAJAT
Sequence: MKTLLLTLLVVTIVCLDLGYTLECHNQQSSQTPTTTGCSGGETNCYKKRWRDHRGYRTERGCGCPSVKNGIEINCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.  Has a higher toxicity than cobrotoxin-b (PubMed:9498573).  In vivo, when tested on rat arthritis models, shows anti-inflammation and immunosuppression effects (PubMed:27840083).
What are the official names of this protein?
Cobrotoxin, CBT, CBTX, CTX, Atratoxin, Cobratide, Short neurotoxin 1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: S20A2_HUMAN
Sequence: MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRRKITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEGTSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV
What is the function of this protein?
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis.  In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions.  May play a role in extracellular matrix, cartilage and vascular calcification.  Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
What are the official names of this protein?
Sodium-dependent phosphate transporter 2, Gibbon ape leukemia virus receptor 2, GLVR-2, Phosphate transporter 2, PiT-2, Pit2, hPit2, Solute carrier family 20 member 2.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPAC_STRU0
Sequence: MSKVLVFGHQNPDTDAIASSYAFAYLAKNAYKMDAEVVALGEPNEETAFALDYFGVTAPRVVESAKAEGVDTVILTDHNEFQQSLSDISDVTIFGVVDHHRVANFETANPLFMRVEPVGSASSIVYRMYKENNLEVPKEIAGLLLSGLISDTLLLKSPTTHMTDHKVAEELANLAGVNLDEYGMSLLKAGTNLASKSEAELIDIDAKTFELNGNAVRVAQVNTVDIAEVLERQDAIETAISDAIVKEGYSDFVLMITDIVNSNSEILALGSNMDKVEAAFNFKLENNHAFLPGAVSRKKQVVPQLTESFGA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SYNC1
Sequence: MIPIVLQTDFPNLKLVNKGKVRDIYDLGEHLLIVTSDRISAFDVVMNEGIPYKGFVLTQISKFWFDAFSDIVPHHLVSTEVDDFPAETRPYRDQLEGRSMLVRKAEPLPIECIVRGYLAGSGWKEYRQQGTVCGIALPPGMVESQKLPEPIFTPSTKAELGAHDENISFEKATELCGGDIAAQAREVALTIYGRARDEMAAKGIIVADTKFEFGLRDGRLMWIDEALTPDSSRFWPQDEYRQGGAQPSFDKQFLRDYLETLDWNKQAPAPTLPDDIVLKTSEKYLEALFRITGLKP
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS17_STRMU
Sequence: MERKQRRTLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNIAKAGDIVRIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y1351_DESHD
Sequence: MRIAIVGGQNHNQETYGKLLGKTGRVEIHFYDGIPKKHNKRNLEKLIKDVDLVIVILGACSHASMWDTKKAAKKCHKEVLFSRGIGISSIVKQIAGKPAYTA
What are the official names of this protein?
UPF0751 protein Dhaf_1351.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: PARC_RICCN
Sequence: MKEAKVENIDFGNALSERYLAYALSTIMSRSLPDVRDGLKPVHRRLLYAMLQLRLEPNSGYKKCARVVGDVIGKYHPHGDVAVYDTLVRLAQHFSLRYPLIDGQGNFGSIDGDNAAAMRYTESRMTDICTLLMEDIDKDTVDFRPTYDGSDLEPVIMPASFPNLLANGSEGIAVGMATNIPPHNLHELCDALIHLINHPKAEINDIINFVKGPDFPTGGIIIDKAEVINAAYTTGRGSLRVRSRWEKEELSYGTYQIVVTEIPYQVQKSKLIEQIAILLKDKKIPLVSNIRDESTDIIRLVIEPRDRGCDPQIVMESLFKLTNLESRIQLNMNVIGSNNVPRVMNILEILQEFLYHRQNIVTRRSTYLLNKIKHRLEILKGLRIAYLNLDEIIKIIREEDEPKAIMMEWFKLTEIQVEAILNTRLRSLRKLEEQEIINEHSNLQKQQAILEEILNNPKELWKIVKKEIKTVQTKFGLNTVIGARRTSFEEVTLTNQVVDITAFITKEPITIICSKMGWVRSLKGHNTDLSTIKYKEGDAEKFILEAYTTDKILIVSSEGRFFTLLADNISKGKGTGESIKLLVDIGNNDITNILVYKPDQLLLLASSVGKGFLVNSNEVMAQTKTGKQIMNVPDGHVCIACLPVNGDSIACIGESRKLLVFNIDEIPEMKKGQGVTLQKFKNAKLLDIKIFNKEDGLGWNNNGKVKLEKNIVAFLGKRGSTGKLPPMGFPKNNRFSSY
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YHLC_SCHPO
Sequence: MSEVQIVKSFLEELSKTPRNHPDSIPIEKIDETAISITIPAPLVEFQGNLALFEEKKVHVVAKTVRPPIQQASTEINVQSTILELKEVLASQLSTQPSSIRLMYKGKPLVNSRLLDDYVDADSVSEVNLQMFLMNIS
What are the official names of this protein?
Uncharacterized ubiquitin-like protein C800.12c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSB6_ENCCU
Sequence: MLSNKRGIHSASGGIDLRTLREYCLFEDFDVCMPFNPMGVPGGKGNRGSDGAIRGMLPLGDAMGDLFTAGKAGSTKMEDKERFDPYEDNSGTTICLKQGDFIVVAGDTRHSSSMVINSREMSKIFQVGDFLLTGTGFYADTHEVYVKMVYEIRQYEVDDSINIHSAANLLSKILYSKRFFPYYSFCVLSGFEKGKPYVYSYDPIGSFGSVTCVCSGSGRSMIQPLLDSFIDKKNWNNAEETQLSQEDCIRLVVKAFNSAAERDVKTKDNLEVCVMRENQVMRETFPLRRD
What is the function of this protein?
Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit beta type-6, 26S proteasome beta-type subunit PRE7, Multicatalytic endopeptidase complex subunit PRE7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_XYLFM
Sequence: MSRYFGTDGIRGRVGQGLISADFVLRLGNALGRVLAQGRDTRPMVLIGKDTRISGYMFESALEAGLVAAGADVQLIGPMPTPAIAFLTNTLRADAGVVISASHNPHDDNGIKFFSAMGEKLDDATEAAIEAAIEAPFLTVDSEYLGKVKRTRDAIGRYIEFSKASVSRGFTLRGLKLVLDCAHGATYHIAPMLFRELGAELVAIGVDPDGLNINAGVGSTHLETLAATVRESGADLGIAFDGDGDRVLMTDAQGRTVDGDDLLYVLARAWRASGRLKGTVVGTLMSNYGLEQALGTLGIPFIRAKVGDRYVHQALVESGGVLGGEASGHLLCLDRATTGDGIVSALQVLEVLRHEGLTLSQALLGLHKVPQKTVNVCWSGPARAAVEMPEVRQALVEAQAAVQGRGRVFLRPSGTEPVVRITVEADDVVLMQQTLDRLADVVRDAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ACRC_ANAPI
Sequence: MFLLKIKKERMKRMDFSLTREQEMLKKLARQFAEIELEPVAEEIDREHVFPAENFKKMAEIGLTGIGIPKEFGGSGGGTLEKVIAVSEFGKKCMASASILSIHLIAPQAIYKYGTKEQKETYLPRLTKGGELGAFALTEPNAGSDAGAVKTTAILDSQTNEYVLNGTKCFISGGGRAGVLVIFALTEPKKGLKGMSAIIVEKGTPGFSIGKVESKMGIAGSETAELIFEDCRVPAANLLGKEGKGFKIAMEALDGARIGVGAQAIGIAEGAIDLSVKYVHERIQFGKPIANLQGIQWYIADMATKTAAARALVEFAAYLEDAGKPFTKESAMCKLNASENARFVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVIAREVMKR
What is the function of this protein?
Probable catalytic subunit of the acryloyl-CoA reductase complex involved in the pathway of L-alanine fermentation.  Catalyzes the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA.  It can also use 3-buten-2-one as substrate.
What are the official names of this protein?
Acryloyl-CoA reductase (NADH), Propionyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_DEHM1
Sequence: MEIIRGFAPAEKRLSRRDKAGFFLDETQRAELAKRLGVDPEKAVNGIIDDIRKQGDKAVLEYTLKFDRAAISKLEVSPAEIKQAAGEIPAELFEALKLAATQVRAYHHFQKEAVWKAAEIMQGKQLIRPLERVGLYVPGGKAFYPSTVLMTAIPAKEAGVDEIILVTPPGADGKIPAPTLAAAYIAGVDKVFACGGAQAVAALAFGTKSIPKVDKICGPGNIFVTLAKKAVFGVVDIDGLQGPSEVLILADQYANAEYCASDILAQAEHDVLASPIMVTTSAELAKRVNDIVETKAGSCARKDIIRQSLRDNGLIAVVDNMDEAIKLANMYATEHLCLLVKDSEQYLSRINHAGCIFYGEKASVVMGDYVAGPSHALPTSGTARFSSPLNILDFVKYIDIVNVSKEEVTKLGKAAVTIARAEGLECHAEAALKRME
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: PNP_RUEST
Sequence: MFNVTTKTMQWGEETLTLETGKVARQADGTVIATLGETSVMANVTYAREQKPGQDFFPLTVHYQEKYYAAGKIPGGFFKREARPTEKETLTARLIDRPIRPLFVPGFKNEVLVMCTVLSHDLVNDPDIVAMIAASAALTISGVPFMGPIAGARVGYEDGEYILNPTVDDMQDLRLNPEQRLDLVVAGTKDAVMMVESEAYELTEEEMLGAVTFAHEQIQPVIDLIVSLAEETAKEPFDFTPPDYSDLYAAVKAAGEEKMRAAYAISDKQERVAAVGAAKEEIIASLTEEQQEDGNLGSALKKLESVVLRGDVVKNGRRIDGRALDQVRAIECQTGLLPRTHGSALFTRGETQGLVVTTLGTGDDEQFIDALHGNFKSNFLLHYNFPPYSVGEVGRVGSPGRREIGHGKLAWRALQAVLPAPTDFPYTIRVVSEITESNGSSSMASVCGGSLSMMDAGVPLKAPVAGVAMGLVLEEDGSYGILTDILGDEDHLGDMDFKVAGTEAGITSLQMDIKVAGITPEIMKNALAQAKAGRLHILGEMAKSLTEASEFSQHAPRIETMQVPTDKIREVIGSGGKVIREIVEVSGAKVDINDDGVIKIASANGEAIQKAYDMIHAIVAEPEEGAVYTGKVVKIVDFGAFVNFFGKRDGLVHVSQIENRRLNHPSDVLKEGQEVKVKLLGFDDRGKVRLSMKVVDQETGEEIVAEKKEAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_MYCBO
Sequence: MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPSDIDRLTGVLAKVRDGVRFCAVCGNVSDNERCRICSDIRRDASVVCIVEEPKDIQAVERTREFRGRYHVLGGALDPLSGIGPDQLRIRELLSRIGERVDDVDVTEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRVLA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RK32_PIPCE
Sequence: MAVPKKRTSISKKRIRRNIWKKRGYWEAKRAFSLAKSISSGRSKSFFVLQKNKQ
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YFEO_SHIB3
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPGLIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMNQMKNPVLVLGIGGFILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRPKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVA_STRZT
Sequence: MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEDQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: HAS1_CANGA
Sequence: MAQTKRSRDESEKEEVVVKADVESSDVDHSFKSLNLSQPTMRAIEKMGFSKMTPVQARTIPPLMAGRDVLGAAKTGSGKTLAFLLPTIELLHSLKFKPRNGTGVIIITPTRELALQIFGVVRELMEFHSQTFGIVIGGANRRQEAEKLMKGVNLLVATPGRLLDHLQNTKGFIFKNLKALVIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLSRISLRPGPLFINVVSEHDSSTADGLEQGYVVCESDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTNGKGKSLMFLIPNELGFLRYLKAAKVPLNEYEFPTNKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFPVPPKVNITIGASGKTPTVVKKRKTHKH
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: INTG_BPPF1
Sequence: MTVRKDGKTWTADFYENGRSGRRIRKKGFATKSAAIRYEQDFFAVKGETGRPLDDRLSDLVKVWYDLHGCTLKDGKQRLARCEALAKRLGNPLAFEFDSLAWARYRQRRLTEVKPETVNHEQRYLSAVFSELIRLGSWHKENPLGKVRQIKTDQVELTFLSLDQVARLLEECKASTNNHTYPVALLCLATGARWEEAESLTRGAVHGGKVHYHRIKNRQSRSVPIPDELERLIFKVGMPGSGRLFMSCRAAFRCAYQRCGFQTPGQMTHILRHTFASHYMMGGGDILTLQRILGHSSITMTMRYAHLSPEHLASAMSLSPLYQIKHFASQVHQ
What is the function of this protein?
This protein may encode an integrase, which is necessary for integration of the viral DNA into host genome.
What are the official names of this protein?
Putative integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: DEOC2_STAAB
Sequence: MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVKYAAERLDDSGVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLNHDEIVKASELTKAAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 2, DERA 2, 2-deoxy-D-ribose 5-phosphate aldolase 2, Phosphodeoxyriboaldolase 2, Deoxyriboaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_ACTP2
Sequence: MRILGIETSCDETGVAIYDEEKGLVANQLYSQIEMHADYGGVVPELASRDHIRKTLPLIQEALKEANLTAADIDGVVYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHLMAPMLEDNPPAFPFVALLISGGHTQLVKVEGVGQYEILGESIDDAAGEAFDKTGKLLGLDYPAGVAVSQLAEKGTPNRFVFPRPMTDRPGLDFSFSGLKTFAANTINANLDENGRLDEQTRCDIAHAFQQAVVDTIIIKCKRALQQTGYKRLVMAGGVSANKQLRTDLAEMMKNLKGEVYYPRPQFCTDNGAMIAYTGFLRLKNGETSDLSISVKPRWNMTELPDISTTGG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GR22A_DROME
Sequence: MSQPKRIHRICKGLARFTIRATLYGSWVLGLFPFTFDSRKRRLNRSKWLLAYGLVLNLTLLVLSMLPSTDDHNSVKVEVFQRNPLVKQVEELVEVISLITTLVTHLRTFSRSSELVEILNELLVLDKNHFSKLMLSECHTFNRYVIEKGLVIILEIGSSLVLYFGIPNSKIVVYEAVCIYIVQLEVLMVVMHFHLAVIYIYRYLWIINGQLLDMASRLRRGDSVDPDRIQLLLWLYSRLLDLNHRLTAIYDIQVTLFMATLFSVNIIVGHVLVICWINITRFSLLVIFLLFPQALIINFWDLWQGIAFCDLAESTGKKTSMILKLFNDMENMDQETERRVTEFTLFCSHRRLKVCHLGLLDINYEMGFRMIITNILYVVFLVQFDYMNLKFKTD
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 22a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CITX_ECOL6
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHAWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: SL9B2_HUMAN
Sequence: MGDEDKRITYEDSEPSTGMNYTPSMHQEAQEETVMKLKGIDANEPTEGSILLKSSEKKLQETPTEANHVQRLRQMLACPPHGLLDRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane (PubMed:18000046, PubMed:28154142, PubMed:22948142, PubMed:18508966).  Contributes to the regulation of intracellular pH, sodium homeostasis, and cell volume.  Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells (By similarity).  Involved in sperm motility and fertility (By similarity).  It is controversial whether SLC9B2 plays a role in osteoclast differentiation or not (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 9B2, Na(+)/H(+) exchanger NHA2, Na(+)/H(+) exchanger-like domain-containing protein 2, NHE domain-containing protein 2, Sodium/hydrogen exchanger-like domain-containing protein 2, Solute carrier family 9 subfamily B member 2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Strong colocalization with LAMP1 and TCIRG1 in osteoclasts. In beta-cells colocalizes with RAB4A and SYP. Localizes to the basolateral membrane of polarized osteoclasts.