PharMolix/UniProtQA huggingface dataset:
Protein: TAU_MOUSE
Sequence: MADPRQEFDTMEDHAGDYTLLQDQEGDMDHGLKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPNQEDQAAGHVTQGRREGQAPDLGTSDWTRQQVSSMSGAPLLPQGLREATCQPSGTRPEDIEKSHPASELLRRGPPQKEGWGQDRLGSEEEVDEDLTVDESSQDSPPSQASLTPGRAAPQAGSGSVCGETASVPGLPTEGSVPLPADFFSKVSAETQASQPEGPGTGPMEEGHEAAPEFTFHVEIKASTPKEQDLEGATVVGVPGEEQKAQTQGPSVGKGTKEASLQEPPGKQPAAGLPGRPVSRVPQLKARVASKDRTGNDEKKAKTSTPSCAKAPSHRPCLSPTRPTLGSSDPLIKPSSPAVSPEPATSPKHVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
What is the function of this protein?
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity.  The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.  Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.  The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
What are the official names of this protein?
Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: FLGH_DESPS
Sequence: MTYRRIPLYLSCLFLLALSGCNSKRPPLVEIPEPLEELQTMSPATRQAGSLWDSNQNSLFSDRKASNVGDIVTVLIEEKSSASKNASTKTGKDSSIGASIPNLFGLEKSSIIANNHIDMNNLIGASFKNDFKGAGSTSRSGTLSAALSTQVIVKYPNGQLKIRGGKEVMVNNEVQVIYLTGIIRPVDITAANTINSDKILNARISYTGKGALGDKQEPGWLTRSLDHVWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ARGB_METLZ
Sequence: MNNRQSVLMEALPYIRKFHKKTIVIKLGGHAMVDSAIMNSVVQDAVLLHYVGMRVVLVHGGGPEITLKMKALGKEARFVGGLRVTDEETLEIAQMVLAGKIGNMIVSMIAKNGAKGVGISGNDGGLVIAEKTPIRKMMVGDEEVEVDLGFVGDVKEINSNLLETLLDAGYIPVISPLALDRKGNDLNINADTMAGEIAVALKAFKLISLTDVDGVMNKERTEIFHRLTLKNVDALMSDGTISGGMIPKLEASVNAVRHGVEGAHILNGNSEHNLLLELFTNDGVGTMITASMISL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_XYLFT
Sequence: MALQFQLNQTTPQTVTTDCVIVGIYADKTLSPTAKTLDAASGGRITALTARGDLTGKSGTSALLHDLNGVTAPRVLVVGLGEADKFGAGQYIKAVGNAVRALKDAPVTHALLTLSELPVKDRNAAWNIHQAVIAADHAAYRYTATLGTSRKKAEESGLITLAIHGQETSGLTLGQAIAEGVEYARALGNLPPNICTPAYLAETTAHFAATHPGATCEILDESNMEALGMGALLAVARGSANRPRLIVLKWNGGGDARPYVLVGKGITFDTGGVNLKTQGGIEEMKYDMCGGAAVIGTFVAAVKVRLPLNLIVIVPAVENAIDGNAYRPSDVITSMSGKTIEVGNTDAEGRLILCDALTYAERFKPEALIDVATLTGACMIALGRAATGLMTHHDDLANELLTAGEHVHDRAWRLPLWDEYQGLLDSTFADVYNIGGRWGGAITAGCFLSRFTEGQRWAHLDIAGSASNEGKRGMATGRPVGLLTQWLVDRC
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V3_SPTNK
Sequence: MLSFLNLNKDSKPFAKIAGGKFKGKKAYVNEESDKGKNELVVPEGKFVPYPNPMYREVIYIAGQSGSGKSTYAAQYIYHYKKLFPKNKVFVFSRLKMAEILVSLGCIEIPIDDELQDMDAIRDIKDALCLFDDIDTIKEKHLRNTVYDIQNDILETGRHNNIYIIVTSHLINGNDKKNTRTILNEAHKVTFFPKSGAYGITYFLKNYIGLPKKQIDNVLEIKSRWITINKGYPLFIFYENGAKTL
What are the official names of this protein?
Uncharacterized protein V3.
Protein: LEG1B_DANRE
Sequence: MSEMGFLRSVAAVLLLAVFSHAAVVTENGLPIQWRKAPSDLSHLPISNTGVQVNPWVYSQRMTMLKMVINATNAYMSSMGPGEQENPLWSLPLQLGWKLKSGRLADPTPDSSSTCGSEASDPVCISPLSFFGCVNYYLSVLPFLAAVETGVVSSGGHQMLIQVPAEVAQDYCSSYSDCSTKHPNTMAKWHLFFQSLRQVSQSKESDFNKKDSILGLMWAAEEESIQTASGACTERQKLYSSPEVSFQQSSVNLGAFISAAHYHASIERSGKFMSHLPSRVLQEADSPPNIADLSTEENHALYMLSWMNSINQLLGGSLVDLWRKAMCSAQAREKGQAFLDDLILDPKFPGSSLWSIICVMSTSC
What is the function of this protein?
Involved in early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation.  In liver, its function is partially redundant with leg1a function.
What are the official names of this protein?
Protein leg1b, Leg1-B, Liver-enriched gene protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the LEG1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOD_GLAP5
Sequence: MTPHINAPAGAFADVVLMPGDPLRAKYIAETFLENAEQVTNVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGAVRQDVKLREVIIGVGACTDSKVNRIRFKDNDFAAIADFDLTLAAVQAAKAKGINVRVGNLYSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALESVLIGDQQG
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TM268_BOVIN
Sequence: MACEPQMDPGGAAGPLPTSSPGWSPLPGGSPPGWGQELRSGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNHWAGVLLVTLAATSLTLTLVVIFERHQRKANTNTDLRLTAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLETCAQFLSDHIREMKMSQESLLRSRLSQLCVVMETGVSPTANEGPENLLEETPLLPDRPGSTEKPLMQTELRQLVPEAEPEEMAQQLLAVFGGYYTRLLVTSQLPQALGTRHMDSPRIPCPCQLIEAYILGTECCPFLTR
What are the official names of this protein?
Transmembrane protein 268.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF1_ACET2
Sequence: MFEKFQAAENRYDEINHRLSDPAVIANQDEYKKLMKEHAELEVLVTKYNEYKKLTKEIADAKEMLNEKLDKEFREMVETELKEAQEKLEVLKKEMKILLLPKDPNDERNVIVEIRGGAGGDEAALFAGDLFRMYTRYAERNGWKTEILDSNPTEIGGFKEVVFSIEGNGAYSRLKFESGVHRVQRVPVTEANGRVHTSTVTVAVLPEAEEIDVEINPNDLRIDTYRASGAGGQHINKTDSAIRITHLPTGLVVCCQDQRSQHKNKEKAMKVLRSKLYEMAREQQHNEIAQERKSQVGTGDRSERIRTYNFPQGRVTDHRIGLTLYKIDDILDGDIDEIIDALITTDQASKLANGAEDDED
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOB2_SCHPO
Sequence: MFLLNSLSRITRGNRSKRHQNLSDASSSSGSFSKKSSTSQLVRTGSPSVEPTALYLQQPFVRTHLVKGNFSTIVSLPRFVDLDEWVALNVYELFTYLNHFYDVFATFCTVKTCPVMSAAANFDYTWLDNNRKPVHLPAPQYIEYVLAWIENRLHDQNVFPTKAGLPFPSNFLVIVKAIYKQMFRIFAHMYYAHYAEILHLSLEAHWNSFFAHFIAFGKEFQLLDKRDTAPLKDLIVVLENQGNI
What is the function of this protein?
Required for coordinating polarized cell growth during interphase with the onset of mitosis.
What are the official names of this protein?
Maintenance of ploidy protein mob2.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Localizes to the cell periphery and to the division site during septation and cytokinesis.
Protein: PRSA_STAAS
Sequence: MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHIIKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS18_HUMAN
Sequence: MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S18, Ke-3, Ke3, Small ribosomal subunit protein uS13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG2_CRYNJ
Sequence: MFSLPSFLTTFSFTLPSLPSISLPANIQRRFLSYVLKRTLGRFVSHQALDAERIQAQVSEGWVEIENLEIECSEINNYIPPPLPLSLTSGTINKLTAKLPFPNLWSDPLQVSLDTLTLDFTLSSPSPLSRGRAATRPEHHDLAESVTSAADDFLHHELDAYEEKELEGSIRQSLILSQTDPFISDVPGGFPLGSPGEISPGRPLPANMESTTVLAGMVERILARLEFRVEKIKIRLVIEDEEDVVELTVGRIRYADESEAQTNDDGKSTTRAIRISNISLDIVPSQRKPPSLVIPQRQSLEPSVSSSTSTASTSSGNDYSDMFMSQAVVDLRQSLLTPEQISEPANEQTVHESNMFYSALSQPNESEPGASTGIKRSGISQNPKLADEIEEERSRSETPTPETKPQPSGIPVLSFGQEDVVLHMRTTRPLISAGHQTSFNDNKPTVEMNITIGTITTVLLPSHLKLFISALQTLQALCQKDDVPAAKDKPAQSTSPQTRLTATTKLKAFYVSLVYDLSAETSLNLHSTMASHLTRPTNPIPYPHLRFRLDTLVASYQSPGHSNPSRPAFTRPTPNMSTANLRRKSSGHARFGSLPSNLTVNVGDISLFEWMGEGMIAPVILFDPGLKHQYDLPSAPPHKGQAGFPECECRDWREEKKTGSEKAWRVRPRGRGILKGGARATTEDEGPVVHVRQDLGSDSAAVINLQSLHVFVDLSLIERLLPLLRSVTPLIHPPEPTPAWLQSVPSQSISEEITPESIISSLSAPPPTARGKKMKADIRCDLVRLSVRCPAPPPEPAERQIGDGRQLRSGIVFVDVHGLKSRFMDTSRTGTRPASSEVANVEFEQTLIFFASVSQHYAYPFLIFAPLSPEPGEEDIPLLPSISLSSFPQASSLPASSIAKTTLVTCKMPAIRASVHHPTVTGLQYFADDVTRWLDVAFADGSAKPRDELKMIGSRFFGGSKGSEASSEIDEPYDVEEVAAGMKVEIEISEIDMGLYVPRLDASGERVFSFKANDLGVRMETHPEENETALELSIMDLDFSDVSSTPLRILGRTTPFTLTSHQAPVVYLRFVSSTDLRTTLKESNISVALSHFTFAVHKEIAWLHEIAQFAKPPKGVFENLSPTDLTRLSINLSSASFLLVPPNLPGSIVILVREVEGKTEIPKGATDSVLEVGMSGLGALAVEGESGPLEVSSDLADVWKKAGYAQLAEVMVLELRLMRELVAAGEVSLDITQAQFKVTACADSLATFAEIATDFGHSLDENAFNLLPEIVSHSDTDMIEDDLPHNLDYLDHATRISKHYPSMDRTTGENLRAWHTPEEGLEEGEWENGESGETIRAFGGEIEEEEGYWEGLPILNDVYSADQKPGKIHIRVLDASLKIFLHDGYDWPRTRKAIEDEVRAVRRRLERIRQLLASGQKADESIENATSSVLFNSIYIGLEQKGEMGLSTMGMGKMDEKALMAAIDEELDGMETESGSSWQTLPAGVGAGPSAVHQAHKKTRLKGKRLVRSKKAQIEITLSGIKTDVDLYPTEESTSSRVHFTAKEMEILDHIKTSTWKKFLTEMKADNRGNIRETDADMLRIELVGVRLKEDEEELRLRAKILPLRLHVDQDALDFLKRFFSFKAPPMTSARPLAQHTTSSTPDLYFQHVEIFPIQLKLDYKPKRVDFRALREGKTIELMNFFHFEGAEMTLRHITLSGITGLERLGTTLQDLWTPDVKANQLADVISGVSPIRSMVNVGSGVADLILLPIEQYRKDGRIAKGVQRGTNSFVKSTALEVMKLGARLATGTQVILERAEGVLGGKSGEDVVGQVQGLSTNAFGVDSGMLEGGSSSEDEQEAISRYADQPESMKEGVQAAYKSLSKNVNAAAQTILAVPMEVYERSGDDGPLKAVIRAVPIAVLKPMIGTTEAVSKTLLGMRNSLDPSARRELDDKYK
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: DNAK_BRUO2
Sequence: MAKVIGIDLGTTNSCVAVMDGKNAKVIENAEGARTTPSIIAFTDGDERLAGQPAKRQAVTNPEGTLFAVKRLIGRRYDDPMVTKDKDLVPYKIVKGDNGDAWVEVHGKKYSPSQISAMILQKMKETAESYLGETVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKSEGKTIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDIRLVEYLVAEFKKESGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADQTGPKHLAIKLSRAKFESLVDDLVQRTVEPCKAALKDAGLKAGEIDEVVLVGGMTRMPKIQEVVKAFFGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDADIEKMVKDAEANAEADKKRRESVEAKNQAESLVHSTEKSLAEYGDKVSADDKKAIEDAIAALKTSLEGEDAEDIKAKTQALAEVSMKLGQAMYEAAQAAEGAGAEGGEQASSSKDDVVDADYEEIDDNKKSS
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LEG3_CANLF
Sequence: MADSFSLNDALSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPRMLITILGTVRPSANRLALDFKRGNDVAFHFNPRFNEDNKRVIVCNTKLDNIWGKEERQAAFPFESGKPFKIQVLVESDHFKVAVNDAHLLQYNHRMKNLPEISKLGISGDIDLTSASYAMI
What is the function of this protein?
Galactose-specific lectin which binds IgE.  May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.  Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.  In the nucleus: acts as a pre-mRNA splicing factor.  Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.  Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes (By similarity).
What are the official names of this protein?
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, IgE-binding protein, Laminin-binding protein, Lectin L-29, Mac-2 antigen.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: DTPLD_HEMLE
Sequence: MAHCYYNSKRGCNRVMKTVALVVLISTVMVEESRGDSQEDKKRPIWNIGHMVNAVKQIEEFLDLGANALEADVTFDDNGNPKWTYHGTPCDCFRDCLRWEYVDEYLKRIRELTSPGSSKFRKGFILLMLDLKISKLSDNAKSKAGKEIADMIIKRLWSGSGEKAQLYIVLSFPYVNDIEFVRAFRERVKSKGFASEAEKRIGWDISGNEDLGKIRDAYQKLGITDNVWQSDGITNCLTRSHDRLAEAVCKRDSDKEWPSLKKVYYWTVDKQSSMKEALKVGVDGMITNDPDDLVAVLNEFSGTHRLANINDSPWQKIPRPKSNC
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with a high activity (PubMed:28335389).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  In vivo, shows dermonecrotic activity when intradermally injected into rabbit skin and is lethal to mice (PubMed:28335389).  Induces increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).  Does not show hemolytic activity (at up to 50 ug) (PubMed:28335389).
What are the official names of this protein?
Dermonecrotic toxin Hl-PLD1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGA_RHOP2
Sequence: MSALTALSIASEIFPLIKTGGLADVTGALPTALKPHGIAMRTLVPGYPAVLGGIENPQQVHSFADFFGGSARLLAARCDELELLVLDAPHLYVRPGNPYVGPDGKDWPDNALRFAALAQAGAAIGQGLLLGYAPDILHAHDWQTGLVPAYLAYSGRPAPKCVFTIHNLAYQGQFPYELLTRIGLPERAFSLDGVEYYGGIGYLKAGLQLADRITTVSPTYALEIQGPDAGMGLEGLLRLRADRLSGILNGIDTRVWDPTADELIPATYDIETIGARARNKQALQSRFGLRNAPDALLYGVISRLSWQKGLDMLLDVLPGMLAEGAQLALLGAGDTPLEQGFRAAALKYPGQVGAVIGYDEALAHQIQAGADALLVPSRFEPCGLTQLCALRYGAVPVVARVGGLADTVVDANEMAIATGVATGVQFSPVTAQMLAKALTKTAALHADHAAWRNLQINGMTTDVSWKNPAQHYARLYRELIDA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: Y1724_ARCFU
Sequence: MEEKFRNCILGLAVGDALGMPVEGLSIENIRQLYGEVRDFLPSPYGDLNAGEWTDDTEQMVVLAESILETVYFDPENFAERLKRWFLETNSRRIGPSSTKAISNLMRGVHWTRAGVFSDTCGAAMRVAPIGLVYHFSLNLVERYAEISARVTHTGTAAIGGAVAVAVAIACNVLDFSDEEMLEEVLRRVEAYDNLLAEKIRYANEISDRDVEYAVEKLGNSISSLDVVPMAFYSYFAGKDFEESLIKAVNAGGDADSIAAICGAIKGAKGFAIPERWLEGLKDREFLEELATKLYELHMRIVKLT
What are the official names of this protein?
Uncharacterized protein AF_1724.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: LIPB_ORITB
Sequence: MVEWIEIQYPIEYSEAYKMMKSRLTGILNGTASEAVFILEHQDVYTAGISAKNDELLNCYDIPVHHTDRGGKFTYHGPGQIIIYPVINLAANGRVKDIRNYVNNLASLVINSLKFFNIIGITVQDTIGVWIDSEFGRKKIASIGVRIHKWITYHGVAINVCPDLKKFKGIIPCGDRDTIVTSINELLDQKIDLDYYKAILKQEFYKIF
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_ECO57
Sequence: MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN512_MACFA
Sequence: MSSRLGAVPATSGPTTFKQQRSTRIVGAKNRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKKHKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPTERERLRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKAGLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNEELVVSASCKEPEQEPVPAQFQKVKPPKTNHKRGRK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 512.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Z587B_HUMAN
Sequence: MAVVATLRLSAQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPVTGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFVKRCKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGEKSNSKTECVSPFQCGGAHYSHGDSMKHFSTKHILSQHQRLLPREECYVCCECGKSFSKYVSFSNHQRVHSGKRPYECGECEKSFSQKSSLIQHQQFHTGGKPYGCEECGKYFSLEGYLRRHQKVHAGKGPYECGECGKSFSSNVNLKSHQRIHTGERPYKCGECEKSFSRKPSLSYHQRFGRPRWVDHKDRKEFKTSLGNIVKSCLF
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 587B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SET5_YARLI
Sequence: MLGLRDVCFDPMLSSYDYHPISLMSTVPNDREIVQAVVDIWRKDKATEKLGAAKLTGLVKLTHSDWQLSEKRVKTVMKAANLGLNQEKFCYAGSIMSHATPGLDMPEKVTLNIAKNRGKGLYAKKDIKKDEELWNEQAFLLVPPLEHVGIMRKGMGCAFCSRPFQSHNGVECPSCAAKWCDNQCKKKDVTHVAMWHESRHGKVTRVEWRAFEDFCVENGWMALYALGLLWLRVIRDPKKDEVQKQMMAFARVGQDERHKAVEQSNSLFASEQSEVLWKKGYEMLDKLLLDTEFSYEKDFLPGLGMFNINNVDGNMYLTQSHLNHSCEPNVDVKNVGRTQGISVRAKRDIKTGEELFTTYVNPEHQLDDRRYNLRVNWGFNCNCTRCKREEREEMEYLDELVSNWTIEHKRKEMKEEKKERTRTRTRSVHFDKEPEVVA
What is the function of this protein?
Putative protein lysine methyltransferase.
What are the official names of this protein?
Potential protein lysine methyltransferase SET5, SET domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL7_ECOBW
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.