PharMolix/UniProtQA huggingface dataset:
Protein: PIMT_XANC5
Sequence: MTPRLRLQPESVGIGMTSQRVRDRLVERLREAGIQDEATLNAMRTVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVTPAKVLEVGTGSGYQGAILAALGLEVYTVERIGDLLRQARKRFRHLGMNVRSKHDDGRIGWPEHGPYDAIVVTAAAPALVDALVDQLAVGGRLVAPVGGPSSQSLVQLTRGADGAIEQQVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBD_LISIN
Sequence: MSVLFYTISFILDFILGDPYSWPHPIKVIGNFIQLLTNALRKIFHGKSLYFAGGLLFILTVGMTGIVSWLILYISAKIAFWLYAAVFIYLGYTTLAMTCLAKEARKIQRTLADGDLEAARVQVGMIVGRDTDKLTAEQISKATIETVAENTADGVIAPLFYLFIGGPVLALMYKAVNTLDSMVGYKNEKYRAIGFVSAKMDDLANFIPARLSWFFLVIASFILKYDGRTAWRIGLRDRKNHTSPNCAYPEGAVAGALGITLGGTHEYFGETVVKPTIGSGTKAVTQKEISQTIHLLYTASIIAFLIFISIHLILF
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOZ_GLOVI
Sequence: MNQPVVETAELMRRVEQLVDAAANRYRITVQVANRAKRRRYEDLNDDDGNFKPVLRAIFEMSDEMNEPEIIGD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PTUA_BACMK
Sequence: MIRIHKDKYFDSIYDELLEQATQEKYMDEYLLEKFMKRYFNGKCSYCEIRMKELRLTIDFYRPINGSLNTMDGEFHPDHYKWLKNEDDNILSICVECKRAKSNRFPVDGDVASINADKNKLVKERRLLIHPCRDYPERHFDYDESGMVYYKSKKGEVTVDVLNLNRGMLVEMRAQVYSEFNNLCYLFSMEQSPYYLKQILQEVQLDSIFIGLKKFILSEWVILNEKIPFLQEFEPLLGKRLQEEEVRVLSVRNNKISQIDIDNNILYVDNDKRRKRVPARKINDYYDVSDENALEKYYGKQRFIEKIEIYNFKSIRNMKIDFTLSKSSNAPWLMLLGENGVGKSSILQAIALTLMGNEQRQKIIKKKPYEYLTKGFDEGSIKIKLSGMQEPISIYLNSNSFEFTGENHQRPRVLILGYGSTRLLPREEMLSNYKVTWARIENLFNPFIPLVNVREYLLSLNNEDFNNVKKAIESLFLDEVIIDRDQIYEEVYFGFANSYSKLEDLSDGYQTIIALATDIMMVMKNRWRNFDAEGIVLIDEIDAHLHPRWNIEIVSRLKNAFPKIQFIATTHNPLSLRGLIDGEVAVLLENEEREAYITQKLPSQKGFNVEGLLTSKFFGLYDTMPDLNELFDRYYLLLSNPSPNERQKEEIKNLQDKLSKYEKVGTTLREQKFYEAVDYYFAQYRKNNVELSDEEFNNIIEDAIKYFER
What is the function of this protein?
Component of antiviral defense system Septu type II, composed of PtuA and PtuB.  Expression of Septu type II in B. subtilis (strain BEST7003) confers resistance to phages SBSphiC and SpBeta (PubMed:29371424).  May be an ATPase (Probable).
What are the official names of this protein?
Septu protein PtuA, Putative ATPase PtuA.
Protein: TBTA_ALTSM
Sequence: MYNNALHGIYLTQITWMKSARAEPYLYYIVTEVEKRNLPIELALMPLIESDFNASAYSHKHASGLWQLTPAIAKYFKVQISPWYDGRQDVIDSTRAALNFMEYLHKRFDGDWYHAIAALNLGEGRVLRAISNIKNKANPLIFQLKTAQTNQSVRAKRTSCGTIIKKPKNAFPAILNSPTIAVLPVDCAVILDNRKQWQQLEIFKPMV
What are the official names of this protein?
Putative tributyltin chloride resistance protein.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
Protein: NADD_SALPK
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLSRVIIMPNNVPPHRPQPEASSAQRKYMLELAIADKPLFTLDERELQRNAPSYTAQTLKAWREEQGPEAPLAFIIGQDSLLNFPTWHDYDTILDNTHLIVCRRPGYPLEMTQAQHQQWLEQHLTHTPDDLHQLPAGKIYLAETPWLNISATLIRERLEKGESCDDLLPENVLNYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: FARS_ZEAPE
Sequence: MDATAFHPSLWGDFFVKYEPPTAPKRGHMTQRAELLKEEVRKTLKAAANQIKNALDLIITLQRLGLDHHYENEISELLRFVYSSSDYDDKDLYVVSLRFYLLRKHGHRVSSDVFMSFKDEEGNFVVDDTKCLLSLYNAAYLMTHGEKVLDEAITFTRRQLEALLLDPLEPALADEVYLTLQTPLFRRLRILEAVNYIPIYGKEAGRNEAILELAKLNFNLAQLIYCEELKEVTLWWKQLNVETNLSFIRDRIVECHFWMTGACCEPRYSLSRVIATKMTALITVLDDMMDTYSTTEEAMLLAEAIYRWEENAAELLPGYMKHFYLYLLKTIDSCGGELGPNRSFRTFYLKEMLKVFVRGSSQEIKWRNENYVPKTISEHLEHSGPTVGAFQVACSSFVGMGDNITKESFEWLLTYPELVKSLMNIARLLNDTASTKREQTAGHHVSTVQCYMLKHGTTMDEACEKIKELTEDSWKDMMELYLTPTEHPKLVAQTIVDFARTADYMYKETDGFTFSHTIKDMIAKLFVDPISLF
What is the function of this protein?
Sesquiterpene cyclase catalyzing the production of sixfold more beta-farnesene than alpha-bergamotene from farnesyl diphosphate.  Involved in indirect defense by producing volatile signals attracting natural enemies of herbivores.
What are the official names of this protein?
(E)-beta-farnesene synthase, Terpene synthase 10.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT1_YEAST
Sequence: MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNVNLKGQSLTNTGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  YPT1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi.  Vesicular transport depends on shuttling of YPT1 between membrane and cytosol by GDI1, probably by recycling it to its membrane of origin after a vesicle fusion event.  Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.  Also involved in the recycling of membrane proteins.
What are the official names of this protein?
GTP-binding protein YPT1, Protein YP2, Rab GTPase YPT1, Transport GTPase YPT1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasm. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side. Note=ER and Golgi when GTP-bound. Cytoplasmic when bound to GDI1.
Protein: COG6_ASPTN
Sequence: MASYFPPGAASSHVSTRSSSPASSPLSPPAQQRSNALSNRLTSVLSASYADSDIRDALETLSLRGIHNTAEVRRQLRLDVQKEVVDSNAEIVRDFGKVAEQLKRIGTVISSLNQTCEEMKKHIVLAKQDTTPVLEEAASLMNQKREAETKQQLLDAFTKHFIVSEEDLLILTSAEEPIDERFFDLLSRVKQVHRDCEVLLGGENQRLGLELMEKSSRNLNSAYQKLYKWIQKEFRSLNLEDPRISSSIRRALRVLAERPSLFHSCLDFFAEARDYVLSDAFHYALTDAVTGAGGDNVKPIEFSAHDPLRYIGDMLAWVHSTTVSEREALESLFVADGEELAKGIQAGLNSEPWSRLDEDETVSFDGQKALSDLVNRDLTGVSRSLRQRVELVIQGHDDPVTCYKVANLLSFYRGTFSKLLGPRSNLADLLETLEKFTLRHFETLMRNQVNTLSADHAALIPSDDLSAPEFLQDALDVLTALMKTHEASFGADVSTDDGDNDSVNRFAPVLRAALDPFLELAKSTADELPNPTARAIYLTNIHLTTRSTIAAYPFASATHLTPLSTALSSLRVDLLAIQHRYLLDASGLQVLLAALEPFSPSSTNGPSDTANDGQQQKQPQPDIADIANLPAFQPDALVATSQQLDDFLPSALMDATDNLKRVQNASFAKSVTEEAVEAFCRDFEFVEGMIIGADEARAKVDVTRDRAVEDDSASDSDKDKDEDGDEDEDAEKGLGLRRLFPRTTGEIRVLLS
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: RAPA_HAEIN
Sequence: MPFAIGQRWLSESENALGLGVITALDQRTVTIYFPAADETRIYAMAQAPLSRIVFSKGETLSHQAGWQGEILDVQNMNGLLFYLVKNPQDEDVIVQERDISPIISFSQAKDRLFSAQIDRSTHFALRYRTLCHQQAQFKSPLRGLRGTRASLIPHQLHIAAEVGNRVNPRVLLADEVGLGKTIEAGMILQNQLFAEKVQRVLIIVPETLQHQWLVEMLRRFNLHFALFDEERCNDFDLDAVNPFTTESLIICSLNWLETHPNRVELVLNAQFDCLIVDEAHHLVWSETSPSTAYLLVEQLARIIPSVLLLTATPEQLGQESHFARLRLLDPERFFDYQTFVKEQEHYQPVVNAVESLLANKALSAVEKNHISDLLLEQDVEPLFKAIASNNDEEQQRARQELIQALIDRHGTGRMLFRNTRQGVKGFPHRVYHQITLSEENDKIDWLIDFLKLHRNEKIFVICQTAATAIQLEQILREREAIRAAVFHEKMSIIERDRAAAYFADLENGAQVLLSSSIGSEGRNFQFAANLVLFDLPTNPDLLEQCIGRLDRIGQKRDVQVYVPCAKDSPQSRLARWYNEGLNAFEQTCPMGMALFSQFADELEKVRSNSTALSENEFSGLLKQTKTAREKLKIELEKGRDRLLELNSHGGEQAQALADQIADEDNSPELVNFALKLFDIIGVEQEDLGANSIVISPTGTMLVPDFPGLKEEGVTVTFDRELALAREEMEFLTWDHPMIRQGIDLVASGDIGKAAMALLVNKQLPAGTLLIELIYVVESQSPKGLQLNRFLPPTPIRLLLDNKGNNIGEQVAFETLHSKLKPLGKNITNQMVKMARSNIESLIMRGDQLVKSLAEPIIAEAKNQADQQLSAEINRLQALRAVNKNIRQSEIDILEQQRTQSLDELSKANWRLDCLRVIVTNKE
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: HBM_BOVIN
Sequence: MLSAQERAHITQVWDLIAGHEAPFGAELLRRLFTVYPSTKVYFRHLGDHPDEVQLLSHGQRMLQAVGVAVQYMDNLRAVLSPLADLHAQVLRVDPTNFPLVIQCFQVVLASHLQGEFTVEMQAAWDKFLTGVAVVLTEKYR
What are the official names of this protein?
Hemoglobin subunit mu, Hemoglobin mu chain, Mu-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HLDE_SODGM
Sequence: MKVTLPDFRRAGVLVVGDVMLDRYWYGPTSRISPEAPVPIVKVDAIEERPGGAANVAMNIAALGCHSRLVGLTGIDDAARALGARLSEVDVTCDFVAVATHPTVTKLRVLSRNQQLIRLDFEQGFDDVDAAPMIERIQLALPKTGALVLSDYAKGALARVREMITLARAAGVPVLVDPKGTDFDRYRGATLLTPNLSEFEAVAGPCKDEETLVSRGMKLIADYQLSALLITRSEQGMTLLQPGKDPLHLPTQAQEVYDVTGAGDTVIGVLAAALAAGNSLEDSCFLANAAAGVVVGKLGTSTVSPIELENAIRGRAETGFGVMTESELKQAVAVARQRGEKVVMTNGIFDILHAGHVSYLANAQRLGDRLIVAVNSDESTKRLKGESRPVNPLAQRMTVLAALEAVDWVVPFSEDTPQRLIADVLPDVLVKGGDYQPHQIAGSKEVWDNGGDVLVLNFEDGCSTTNIINAIKRRAGQRTVV
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: NOSF_STUST
Sequence: MNAVEIQGVSQRYGSMTVLHDLNLNLGEGEVLGLFGHNGAGKTTSMKLILGLLSPSEGQVKVLGRAPNDPQVRRQLGYLPENVTFYPQLSGRETLRHFARLKGAALTQVDELLEQVGLAHAADRRVKTYSKGMRQRLGLAQALLGEPRLLLLDEPTVGLDPIATQDLYLLIDRLRQRGTSIILCSHVLPGVEAHINRAAILAKGCLQAVGSLSQLRAEAGLPVRIRASGISERDSWLQRWTDAGHSARGLSESSIEVVAVNGHKLVLLRQLLGEGEPEDIEIHQPSLEDLYRYYMERAGDVRAQEGRL
What is the function of this protein?
Required for the assembly of the copper chromophores of nitrous oxide reductase (PubMed:2170125).  Has ATPase activity (PubMed:12618453).  Could be part of the ABC transporter complex NosDFY (Probable).
What are the official names of this protein?
Probable ABC transporter ATP-binding protein NosF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: MOAA_METM6
Sequence: MEDRYGREIRSFRLSITPKCNLKCFYCHKEGRNEEHGKLMSADEIVKIVKSSLEFGVRKIKISGGEPLLRTDLPKIIENIKDDQIKDISLTTNGILLEKYAQKLKDAGLDRVNVSLDTLDPVQYKKITAGGNIESVKKGIEKAIEVGLTPLKVNFLAMDCTVKQLPAIMDYCRKIGAILQIIEFIPMEPELKHHHIDVIPIEKEIAKKADQVFTRKFMQNRKKYVIDGLEVEFVRPMDNTEFCGHCTRIRLTYDGYLKPCLLRDDNLVDVANPVRNGEDIRKYFIKCIEEREPFCKAQ
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ANR49_MOUSE
Sequence: MEKEKKDDEKPDLENSVDFSEQFNQLELLKTHGHLIPTGTQSLWVGNSDEDEEQEEKNEEWYQLQEKKMEKDPSKLLLWAAEKNRLATVQRLLSEKAAEVNTRDEDEYTPLHRAAYSGHIDVVRELVAKGADVHAVTVDGWTPLHSACKWNNTKVASFLLQHDADINAQTKGLLTPLHLAAGNRDSRDTLELLLMNRYIKPELKNNSQETASDIARRTSIYHYLFEIAEGCTNSSPPS
What is the function of this protein?
May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 49, Fetal globin-increasing factor, Fetal globin-inducing factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO1_TREPA
Sequence: MQEKKTLYLLDAYGLIYRSYHAFARAPLINDSGANVSAVYGFFRSLHTLLCHYRPRYFVAVFDSLTPTFRHVQYPAYKAKRDKTSAELYAQIPLIEEILCALGITVLRHDGFEADDLIATLAKRVAAEHCHVVIISSDKDVLQLVCDTVQVLRLDIDHKWTCCDAAYVQQRWTVMPTQLLDLFSLMGDSSDNVPGVRGIGPKTAAHLLHCFGTLDGIYRHTYSLKEALRTKIVCGKKDAFFSRSLIELRDDVPCVFSLEDSCCIPLDVTSAARIFVREGLHALAQQYRACVQEIDTEATNDTLQMTESSVLTSGRCANECFLSQVEGRASTPEVNSVLKSELKTSAVSGAIPIENRDLRQDVMLARSAGHYRGVTDPVELKRIIDCACANGVVAFDCETDGLHPHDTRLVGFSICFQEAEAFYVPLIVPDVSLHTESTQCTCARSTNVETEKECTEQHGVSASAVQDPAYVQAVMHQLRRLWNDETLTLVMHNGKFDYHVMHRAGVFEHCACNIFDTMVAAWLLDPDRGTYGMDVLAASFFQIRTITFEEVVAKGQTFAHVPYECAVRYAAEDADITFRLYHYLKLRLETAGLLSVFETIEMPLLPILARMEEVGIFLRKDVVQQLTRSFSDLIQQYEHDIFSLAGHEFNIGSPKQLQTVLFQELHLPPGKKNTQGYSTDHSVLKKLARKHPIAEKILLFRDLSKLRSTYTESLAKLADQTGRVHTSFVQIGTATGRLSSRNPNLQNIPIKSTEGRKIRQAFQATVGHELISADYTQIELVVLAHLSQDRNLLNAFRQHIDIHALTAAYIFNVSIDDVQPAMRRIAKTINFGIVYGMSAFRLSDELKISQKEAQSFIYRYFETYPGVYAFSTQVAEQTRKTGYVTSLAGRRRYIRTIDSRNTLERARAERMALNTQIQSSAADIVKIAMIAIQRAFARRPLRAQLLLQVHDELIFEAPAAETAIVKEILFAEMEHAVELSIPLRIHVESGNSWGDFH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: RNC_CAMJE
Sequence: MKNIEKLEQSLTYEFKDKNLLIHALTHKSFKKSYNNERLEFLGDAVLDLVVGEYLFHKFAKDAEGDLSKLRAALVNEKSFAKIANSLNLGDFILMSVAEENNGGKEKPSILSDALEAIIGAIHLEAGFEFAKTIALRLIEKNFPQIDAKILIKDYKTKLQEITQGKIGQTPQYETVRAFGPDHLKQFEIALMLDGKELARAIAGSKKEAQQMAAKIALEKLGAL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  In this organism endogenous ribonuclease 3 and Cas9 are required for correct coprocessing of pre-crRNA and the trans-encoded small RNA (tracrRNA).  Cas9, crRNA and tracrRNA are required for cleavage of invading DNA (Probable).  Complements pre-crRNA and tracrRNA coprocessing defects in an rnc deletion in S. pyogenes strain 370 (PubMed:24270795).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_STRA1
Sequence: MIKIYDTMTRSLQDFIPLNEGKVNMYVCGPTVYNYIHIGNARSVVAFDTIRRYFEYCGYQVNYISNFTDVDDKIIKGAAEAGMDTKSFSDKFISAFMEDVAALGVKPATKNPRVIDYMDEIIDFVKVLVDKEFAYEANGDVYFRVSKSHHYAKLANKTLEDLEIGASGRVDGEGEIKENPLDFALWKSAKSGEVSWESPWGKGRPGWHIECSVMATEIFGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVNVDNEKMSKSLGNFITVHDMLKSVDGQVIRFFLATQQYRKPVNFTEKAVHDAEVNLKYLKNTFNLPIQENANDEELEQFVKAFQGAMDDDFNTANGITVIFEMAKWINSGHYTSRVKETFAELLEIFGIVFQEEVLDADIESLIEQRQEARANRDFATADRIRDELAKQGIKLLDTKDGVRWTRD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19A_CANAL
Sequence: MANLRTQKRLAASVIGVGKRKVWLDPNETTEIANANSRSAIRKLYKNGTIVKKPETVHSRSRARALKESKRAGRHMGYGKRKGTKDARMPSQVLWMRRLRVLRKLLAKYRDAGKIDKHLYHNLYKAAKGNTFKHKRSLVEHIIAAKAEALREKALKEEAEARRVRNRAARERRQQRLAEKKEALFAEAAN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).  RPL19A may play a role in the last stages of translation initiation, in particular subunit joining and shedding/releasing factors (By similarity).
What are the official names of this protein?
60S ribosomal protein L19-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: RAD5_SCHPO
Sequence: MKRKVQKIIDEAPLEENSPPRFFDSDVEADSKPNDLTAANSIVDLKTNSQHENANAAGKEYGDSGVSESWVLDFLSVTGEKTISEFLAQKIWKTSNGDLNVAVDMYFDESFNIKNSNPDSESQKDTDASLTQMDQLSNTVSVKDLSINRNTNKKALNAVSPSLNLSSNSSVQDVSIDKEEMMKKQSRNALTPLDFIMKKNELMKYIGCFGVEAYSTASGTRTLQAGERIYLERQKLSIKSQSRNSRKKSKLLSINSSCYSNIVRFCNSDHHEIGKLPTEVASVISTLMEQGFWSFEAICIYSDNIIRFGSNVTLQVYCFINVNHPSLNRSPFTLATNSMQEEEEHLKASFAQNKRDHLLRLFTWIALEPDLEDCNTKESIHIDDILKTSSLPEARDESNSDLTPSSTEDEEDVVSDQLAILYDKVKTSGAELPSAPKPSTFALDLREYQKQALYWMCCKEEGVQSDGSAPKLHPLWSRFRFPKDSEFPEFFKCSSDDDNTHFYVNLYTGETTMLFPNSMPYHRGGILADEMGLGKTIEVLSLIHSRPCFSTDEIPEAFRHSKPSLPVASRTTLVVAPMSLLDQWHSEACKVSQGTKFRSMIYYGSEKPLDLKSCVIDTSTAPLIIITSYGVLLSEFSQQSHSSGLFSVHWFRVVLDEGHNIRNRESKTAKACHSISSQNRWVITGTPIVNKLDDLYSLIKFMRYEPWCNYTYWQTFVSLPYQSKDVLKALNVVQSILEFLVLRRTKETKDRNGNSIVTLPPKTVKIEYLDFSDSERKIYDSLYTKAKSTVNANIVAGTLFRNYTTILGLLLRLRQACCDPVLLSNMTINSETFDDFEFSVEQFNSLINQFVVTGKPIPSDILKIDTLKSFEALITECPICCNEPIQNPLLLNCKHACCGDCLSEHIQYQKRRNIIPPLCHTCRQPFNEQDVYKPFFVKNNGTQSTLLVGEEVKWKYWNRLQSVKLNGLLGQLRQLTHSSEPEKVVIFSQFTTFLDIIADVLESEKMGYARFDGTMSQQMRSTALETFRNDPDVNVLIISLKAGGVGLNLTCANHVFIMDPWWSWSVEAQAIDRIHRLGQEKPVFVTRYIVRDTVEERMLKIQERKNFITGTLGMSEGKQQVQSIEDIKMLFEY
What is the function of this protein?
Probable helicase, member of the UBC2/RAD6 epistasis group.  Functions with DNA repair protein rad18 in error-free postreplication DNA repair.  Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats (By similarity).  Plays a role in surviving topoisomerase-mediated DNA damage (PubMed:14871939).
What are the official names of this protein?
DNA repair protein rad8, DNA repair protein RAD5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MESE_LEUME
Sequence: MFDPKYLESGEFYQRRYRNFPTLIIVPIFLLVVFIVLFSLFAKREIVVKASGEIIPAKVLSDIQSTSNNAIDSNQLAENKMVKKGDTLVTFTSGNEKISSQLLTQQINNLNNRIQSLDTYKHSIIDGRSEFGGTDQFGYDNLFNGYMAQVDTLTSEFNQQNSDKQTADQQANHQIDVLKQGQSKNNQQLANYQAILTSINSNTKPTNNPYQSIYDNYAAQLKSAQTTDDKEQVKQTALSSVQQQIDQLQTTSSSYDSQIAGITKSGPLSQSSTLDKIADLKQQQLASAQKEINDQQQSLDELKAKQSSANEDYQDTVIKAPESGILHLTSDKATIKYFPKGTTVTQIYPMLNKRTKLSVEYYVPTSNSVGLKRGQNIRFVANQNVTKPLILTGTIKTISSAPIIIKEESFYKCIASINVNVREHEQIKYGLAGKVTTTKGTKTWFNYYKDILLGNTN
What is the function of this protein?
Involved in the secretion of mesentericin Y105.
What are the official names of this protein?
Mesentericin Y105 secretion protein MesE.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EI2BB_TAKRU
Sequence: MPGADKEVDLTERIEAFLSDLKRGGSGTGPLRGSSETARETTALLRRITAQARWSSAGDLMEIIRKEGRRLIAAQPSETTVGNMIRRVLKIIREEYARSRGSSEEADQQESLHKLLTSGGLSEENFRQHFAALRANVIEAINELLTELEGTTDNIAMQALEHIHSNEVIMTVGRSRTVEAFLKDAARKRKFHVIVAECAPFCQGHKMATSLSTAGIETTVIADAAIFAVMSRVNKVIIGTQTVLANGGLRAVNGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDTFHKFVSPHEVLPFTEGEILSKVNVHCPVFDYVPPELITLFISNIGGHAPSYIYRLMSELYHPEDHEL
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit beta, S20I15, eIF-2B GDP-GTP exchange factor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: RS12_STRZP
Sequence: MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: KEFG_SALEP
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DMD_BPT4
Sequence: MELVKVVFMGWFKNESMFTKEITMMKDDVQWATTQYAEVNKALVKAFIDDKKVCEVDCRG
What is the function of this protein?
Antitoxin component of a potential type II toxin-antitoxin (TA) system.  Acts as an antitoxin against host toxins RnlA and LsoA, preventing them from degrading T4 bacteriophage-derived mRNA and thus permitting successful virus infection.  Stabilizes middle (8-10 minutes) and late (18 to 28 minutes) T4 gene transcripts.
What are the official names of this protein?
Antitoxin Dmd.