PharMolix/UniProtQA huggingface dataset:
Protein: NUOD_RHOPS
Sequence: MAEAPMAQAPTAQAPTAEAAAEAPGLRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVAPMNQEHAFCLAVEKLLGIAVPRRAQLIRVLYCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMMFYERASGSRMHAAYFRVGGVHQDLPPQLVADIDSWCDSFIQVVDDLETLLTDNRIFKQRNVDIGVVTLEQAWEWGFSGVMVRGSGAAWDLRKSQPYECYAEMDFDIPIGKNGDCYDRYCLRVEEMRQSIRIMKQCIAKLRAPDGQGRVAIDDNKIFPPRRGEMKRSMESLIHHFKLYTEGFRVPEGEVYVAVEAPKGEFGVYLVSDGSNKPYKCKIRAPGFAHLQAMDFICRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: APT_BACC2
Sequence: MDFKQHIAIVPDYPKEGIVFKDITPLMNDGKAYKAATDAIVEYAKERDIDVVVGPEARGFIIGCPVSYALEVGFAPVRKLGKLPREVITVDYGKEYGKDVLTIHKDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGVVAGIAFLVELTYLDGRKMLDGYDVLVLEKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_DESAL
Sequence: MAYNAVEMADWQISEAAEENMPTPEQWAEKLGLQSDEMLPMGRLAKVDFLKIIDRLKDRPDGKYIEVTAITPTPLGEGKSTTSVGLMEGLGMRGKNVGGALRQPSGGPTMNVKGTAAGGGNSLLIPMTEFSLGLTGDINDIMNAHNLGMVAMTARMQHERNYNDEQLQRLTGMRRLDIDPTRVEFGWIIDFCAQALRNIVIGLGGRFDGYTMQSKFGIAVGSELMAILAVATDLADLKERINNITVAFDKSGKPVTCGDLEVGNAMAAFMRNTINPTLMCTAEYQPCFVHAGPFANIAVGQSSIIADRVGLKLFDYHVTESGFAADIGFEKFWNVKCRFSGLKPHVSVLTSTIRALKMHGGGPKVVAGKALDDAYTKENLELVEKGCENMVHMIGVIRKAGINPVVCINRFYTDTDAECAIVRKAAEAAGARCAESKHWEKGGEGALEFADAVIEACEEGNDFDFLYPLEMKLRDRVNKIATEVYGADGVDWAPEAAAKAEMLESDPKYADFATMMVKTHLSLSHDPVKKGVPKGWRLPIRDVLIYSGAKFLCPCAGTISLMPGTGSNPAFRRIDVDPATGKVSGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: MURC_BACCR
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKNNVEEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMSQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFADINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC11_CANAW
Sequence: MNIRQQITQFLSLAYVFSSAFMLWKTLSVIANSHSPIVVVLSGSMEPAFQRGDILFLWNRDHQQKVGDIVVYEIDGKSIPIVHRVLREHHNSEKQLLLTKGDNNAVDDLSLYAKKQQYLNQKQDLVGTVKGYLPFIGYVTILISENVYFKYGMLGLLGLSSLFSNE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NTPPB_SHEON
Sequence: MMTPQLILASTSVYRQALLRKLGLPFEYCDPNIDETPIANESAQALVLRLAQAKAEAGAKYFPDGLIIGSDQVAVIDSKIIGKPLNRDNAIQQLSQASGKTITFYTGLALYNAQTGEINAQVEPFTVHFRHLAASQISAYVDKEQPFYCAGSFKSEGLGIALFSRLEGRDPNTLVGLPLILLTEMLLSQGIDVLA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEFM_ECOL6
Sequence: MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Antitoxin that counteracts the effect of the YoeB mRNA interferase.  YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor (By similarity).
What are the official names of this protein?
Antitoxin YefM.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: ATPG_ERYLH
Sequence: MASLKELKDRIGSVKSTQKITKAKQMVAAAKLRRAQANAEAARPYAERLADVMASLAGKVSGDSAPRLLAGSGNDQKHLLVVVNTDKGLCGGLNSNIVKEAKAQAKKLIAAGKDVQFYLVGKKGRAPIKRDYEKQIAKHFDTSTVKQPGFEEADAIANELIDMFEAGEFDVAHLVYPTFKSALVQDPTTNQLIPVPSPEGEGTGGDAVVEYEPGEEEILEELLPRYVKTQLFGALLEREASEQGASMTAMDNATRNAGDLINKLTIQYNRSRQAAITTELIEIIAGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UVRC_HALH5
Sequence: MKDHIKQKLTVLPDQPGCYLMKDRQGTIIYVGKAKVLKNRVRSYFTGSHDAKTQRLVGEIADFEYIVTSSNIEALILEMNLIKKHDPKYNVMLKDDKSYPYLKLTNEEHPRLVTTRKLKKDGGKYFGPYPNAGAANETKKLLDRLYPLRKCRTLPDKVCLYYHIGQCLAPCVYEVTPEQNEQMVQEITRFLKYGHKEVKVELEKKMHKAAEELNFERAKELRDTLGYMEAVMEKQTMMVNDRVDRDVFGYAYDKGWMCVQVFFVRQGKLIERDVSIFPFYKEAEEDFLTFIGQFYLQKDHIKPGEVLLPAGTDAALVEQLLDVSVHIPKRGKKKELVDVAMRNATMALKEKFALIERNEERTIKAVEQLGEAMGIPTPYRIEAFDNSNIQGTDPVSAMVAFIDGKPNKKEYRKYKIKTVTGPDDYESMREVVRRRYVRLLKEQRSLPDLIVIDGGKGQIAAAQEILHDELGLSIPVCGLAKDEKHRTSQLLLGDPPQVVPLKRDSHEFYLLQRIQDEVHRFALTFHRQTRSKTFFQSVLDDVPGIGEKRKRQLLKHFGSVKKMKEASIDDFLALSIPKSVAETLYNKLQTK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
Protein: AC102_NPVAC
Sequence: MIASINDTDMDTDDNMSQARRNRRNRPPARPSAQTQMAAVDMLQTINTAASQTAASLLINDITPNKTESLKILSTQSVGARSLLEPMQANASTIKLNRIETVNVLDFLGSVYDNTIQVIVTE
What is the function of this protein?
Nucleocapsid protein that mediates the translocation of G-actin from the host cytoplasm to the nucleus, which is fundamental to infection.  Participates in regulating nuclear actin polymerization as well as the morphogenesis and spatial distribution of viral capsid structures in the host nucleus.  Suppresses 'Lys-48'-linked ubiquitination of the viral protein C42, thus forming a regulatory cascade with C42 to control P78/83 availability as an nucleation promoting factor (NPF).
What are the official names of this protein?
Protein Ac102, P12.
What are the subcellular locations of this protein?
Host nucleus.
Protein: LONF1_HUMAN
Sequence: MSSPAVARTSPGGSREMAPAPQGRGRFWEVGGGSGHRLERAAAESERWELLLRRGELLALGGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGLGWSAAPVAGADGGAGGLLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLCRDRLPPATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQLFLQCLALDEDFAPAKLQVQKILCDLLLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEESQSLNEPSPKQSEEIPEVTSEPVKGSLNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGRNKLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQILQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTYFSRDQSK
What are the official names of this protein?
LON peptidase N-terminal domain and RING finger protein 1, RING finger protein 191.
Protein: GLO2_CUPTR
Sequence: MLKVEPIPAFQDNYIWAIHDGHCAAVVDPGEAAPVERFLAQSGLALGAIVITHHHGDHQGGVAGLLAAHPRAPSGGPLPVLGPAGERIGGRTQALREGDVATLEAPALTLRVLDVPGHTAGHIAYVADLGEAGPALFCGDTLFASGCGRLFEGTPAQMLASLDKLAALPGDTRVYCAHEYTRSNVRFARAVEPGNAALAAWEARVEALRATNQPTLPTTIAHERQVNPFLRSREPAVRAAVSAHGGTAADDAQNFGALRGWKDNFR
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: MET22_YEAST
Sequence: MALERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVSTSCDVIQSRNA
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS.  Involved in salt tolerance.  Confers resistance to lithium.
What are the official names of this protein?
3'(2'),5'-bisphosphate nucleotidase, 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase, DPNPase, Halotolerance protein HAL2, Methionine-requiring protein 22.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KDSB_METPP
Sequence: MSFTVLIPARLGSSRLPDKPLADIAGLPMVVHVARRALASGAAVVVVAADDTRTVEACARHGVRALLTRRDHATGSDRLAEACDLLALPDSEIVVNVQGDEPLIDPALIDACARLLAERPECVMGTAAHAIDTVAEFENPNVVKVVCDALGRALSFSRAPMPWWRDGYAAGLRQATALSDPPPLRHIGLYAYRAGFLRRYPKLAPSPIETIESLEQLRVLWHGERIAVHVSPLRPGPGVDTPDDLARVRALLHDTGQEPPRESG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR1_BACC1
Sequence: MKKEKRQRLIKQFVKEYEIEKQERLVELLAKKDVLVTQATVSRDIRELNVTKVPSQEGLMIYKIFSEEHLQTDIKLKKKLREVVVKIDCVDQLMVIKTLPGNAHVIGVLFDELDWKEKIGCICGNDTCLIISQSKSDREILEERLNLII
What is the function of this protein?
Regulates the transcription of the arc operon, involved in arginine catabolism.
What are the official names of this protein?
Arginine regulator.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF41_ARATH
Sequence: MTQGKRKHPCDLKNPSKRAPPATCNKPNGAILCGDFCLHEGYNIGKCVMRRTGKACICSQCEGW
What are the official names of this protein?
Defensin-like protein 41.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: RR8_LOTJA
Sequence: MGKDTIADIITSIRNADMNRKRTVQIPFTNITENTVKILLREGFIENVRKHRESDKSFLVLTLRYRRNTKGSYKTFLNLKRISTPGLRIYYNYQKIPRILGGMGIVILSTSRGIMTDREARLEKIGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y3714_MYCGI
Sequence: MTRQGMRDDLRGEADSVVHDGTDDIDNENDIDNGIDNENGNGIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPELIAQMVDLGLAAGSRITQLAAVMDVRSRGFTGDLDWVRSELATRNIVPRVVFLEASDDILVRRYEQNRRSHPLQGNQTLAEGIAAERAMLAPVRASADLVIDTSALSVHGLRDSIERAFAAETVAHTNVTVESFGYKYGLPMDADTVMDVRFLPNPHWIDRLRPHTGQNADVRDYVLGQPGADEFLDSYHQLLNVVIDGYRREGKRYMTVAIGCTGGKHRSVAMAEALAARLAGSDALTVRVLHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Mflv_3714.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: HSP81_ORYSJ
Sequence: MASETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPELFIHIVPDKASNTLSIIDSGIGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLKDDQLEYLEERRLKDLIKKHSEFISYPISLWTEKTTEKEISDDEDEEEKKDAEEGKVEDVDEEKEEKEKKKKKIKEVSHEWSLVNKQKPIWMRKPEEITKEEYAAFYKSLTNDWEEHLAVKHFSVEGQLEFKAVLFVPKRAPFDLFDTRKKLNNIKLYVRRVFIMDNCEELIPEWLSFVKGIVDSEDLPLNISREMLQQNKILKVIRKNLVKKCVELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSTNRNKIAELLRYHSTKSGDELTSLKDYVTRMKEGQNDIYYITGESKKAVENSPFLEKLKKKGYEVLYMVDAIDEYAVGQLKEFEGKKLVSATKEGLKLDESEDEKKRKEELKEKFEGLCKVIKEVLGDKVEKVVVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENAIMEELRKRADADKNDKSVKDLVLLLFETALLTSGFSLDDPNTFGSRIHRMLKLGLSIDEDETAEADTDMPPLEDDAGESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 81-1, HSP81-1, Heat shock protein 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APHA_SHIFL
Sequence: MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQAPIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFWEKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPATNMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTYKPLPQAGAFGEEVIVNSEY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters.  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SEC11_PODAN
Sequence: MLSALGNPRQAAAQLMNFGLILSTAFMMWKGLSVISDSPSPIVVVLSGSMEPAFQRGDLLLLWNRNLFTETSVGEVVVYNVRDKDIPIVHRVISKFGTGFVIPRQWWLFMGIYNNDSDDTKLYAPGQNYLVREDIIGRSVVGYMPFVGYVTIMLSEHPWMKTVMLGIMGLVVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TM50B_MOUSE
Sequence: MAGFLDNFRWPECECIDWSERRNTVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNIDVYPGLAVFFQNALIFFSTLIYKFGRTEELWA
What are the official names of this protein?
Transmembrane protein 50B.
What is the protein family that this protein belongs to?
Belongs to the UPF0220 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RBFA_RHORT
Sequence: MTRTSDKAPTQRQLRVGEEIRHALAEVFERGTVRDPAVAGVALTVTEVRISPDLRNATVFLVRLGGGPLDEVLTGLRKARAFLRREVAIRIHTKFVPDLRFESDPSFDYAEYINGLLHRPEVARDLGVPPSGEDDGDDEADDEDDDGGEEGPGAAAPPPADEGR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_ACTPJ
Sequence: MTIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGHFPESPIFPGVLILEAMAQATGVLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFEVEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_AKKM8
Sequence: MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRTGQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRTRTNARTRKGKKKTVGAQAKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NAGB_STRPG
Sequence: MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDIEAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRFFTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLDSPNQSLNLVRTKMRR
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: Y092_MYCPN
Sequence: MVSKWGAGSAFGLQGNGSNSSGLRPLLKRTAQINLRQTQDNAQTGKFSKYLNTAQALHQMGVIVPSLETWPGKPSTGIATRAVGGVSVQAATRLDFYKWRSAECNNKVIPHLHVPTRLLKWPDRCDGFKRGTEFVVLGCRGGPGIGSRNLMSPHRAQLGHRQAEAVCRKPVGF
What are the official names of this protein?
Putative MgpC-like protein MPN_092.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: LEUC_ENDTX
Sequence: MGNTITEKILASHCGKKVVEPGEFIEPKIDIALSNDVTAPLAVKEFRKTGIKKVFDKNKIALVMDHFTPNKDILSAEHVKFVREFAKEHKIKHYYEGGNVGVEHALLPEKGIVVPGDVIIGADSHTCTYGALGAFSTGGGSTDIAAAMATGKIWFKVPNSIKFILNRKLNKWVSGKDIILYIIGLIGVDGALYNSMEFDGPLCKKLTMADRFTITNMAIEAGGKNGIFTPDEITENYVAKRAQRKYKFYISDKDAKYLKIYEIDCSKILPQVSMPFLPSNTKAVKDIKKTYIDQVVIGSCTNGRIEDLRVAASIIKKGKKVNSNVRTLIIPATPEVYSQALDEGLLRIFMDAGAIISAPTCGPCLGGHMGILASGEKCASTTNRNFRGRMGHVESQLFLVNPAVAAASAIKGYIASPDEI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RDRP_I83A1
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGRWTKNTETGAPQLNPIDGPLPKDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCIETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLMANESGRLIDFLKDVMDSMDREEMEITTHFQRKRRVRDNVTKKMVTQRTIGKKKHRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLRYFNDSTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNYAGIQAGVDRFYRTCKLLGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWDQTRSKTGLLVSDGGPNLYNIRNLHIPEVCLKWDLMDEDYQGRLCNPLNPFVSHKEIESVNNAVMMPAHGPAKIMEYDAVATTHSWVPKRNRSILNTSQRGILEDEQMYQRCCNLFEKFFPSSSYRRPVGISSMVEAMISRARIDARIDFESGRIKKEEFTEIMKTCSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.