PharMolix/UniProtQA huggingface dataset:
Protein: CNBZ_COMTE
Sequence: MPDAVVFSPGGYRYIPAVFQYSAGIAAEPGFEIERVRFHRPVPLAEAFVAVESHLRAIGRPTTSFAQCELRSPDPFNDQGFIDFNTEYVKTLERWGIYKDRVNPVARTNVCPMYDKPTTPSMFAFSYTVPTTSAAKRPSFQLAGGGDARGGSAPYKDRIVAFGDTSPEGLREKVVFVIEEMESRLKTLGLGWADAVSTQLYTVQNIGHLVGPELARRGCGAGGLVWNYTRPPVIGLEYEMDVRGAVRETVL
What is the function of this protein?
Involved in the biodegradation of xenobiotic compounds, such as nitrobenzene and 4-chloronitrobenzene (4-CNB) (PubMed:16517619).  CnbZ preferentially catalyzes the deamination of 2-amino-5-chloromuconate (2A5CM) to yield 2-hydroxy-5-chloromuconate (2H5CM).  Also able to catalyze the deamination of 2-aminomuconate to yield 2-hydroxymuconate, which spontaneously converts into its keto form, 2-oxalocrotonate.
What are the official names of this protein?
2-amino-5-chloromuconate deaminase, 2A5CM deaminase, 2-aminomuconate deaminase (2-hydroxymuconate-forming).
Protein: PTG3C_STAAR
Sequence: MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGEALQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQTGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICBA component, EIICBA-Glc, EII-Glc, EIICBA-Glc 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2173_BACAN
Sequence: MSNAYEEYMRQMVIPMRQELVRSGFEELTTEEAVTEFMENTTGTTLVVVNSVCGCAAGLARPSAGQAVVRAEKQPDHLVTVFAGQDKDATAKMREYFGEIPPSSPSMALLKGKEVVHFIHRHEIEGATMDEIITNLEQAFEKNC
What are the official names of this protein?
UPF0403 protein BA_2173/GBAA_2173/BAS2019.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: YKGH_ECOLI
Sequence: MREQIKQDIDLIEILFYLKKKIRVILFIMAICMAMVLLFLYINKDNIKVIYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFHTSPDVKNREIRLEWSGDKRALPTAEEEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIYLTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQNSGQ
What are the official names of this protein?
Uncharacterized protein YkgH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCB_PSEFS
Sequence: MGTPCHFALFELQPNFRLDLEQLATRYRELARGVHPDRFADASEREQRLALEKSASLNEAYQTLKNPPKRARYLLAMNGGEVPIEVTVHDPDFLMQQMQWREELEDLQDEADVAGVAVFKRRLKTAQDELNESFAACWNDAAQREQAERLMRRMQFLDKLTYEVRQLEERLDD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: CSPLL_POPTR
Sequence: MTAPTAPSMAAPPAPSMVSRMTALFLRVLTFAFLMVSLVIMTTNTGTIEIGIDEFKVRSKDFYSYRYMLAAIAFGLTYTILQIALTLNHISKRNGAQTSGDGNLVFDFYGDKVVSYILATGAAAAFGATKELKTQLAGLGGDKFFNKGYASASLLLLGFVCTAILSVFSSYALPKKV
What are the official names of this protein?
CASP-like protein 4D1, PtCASPL4D1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMC_HAEDU
Sequence: MRRALIFLASPHFFAPNFFIFIYAKRISTPQIPLFIRPQGFFQTNPKVASQLYATVQQWVKILPINHLWDLFCGVGGFGLHCAKALQDQGKPVTLTGIEISAAAIESATQSAQKLALNNVTFASLDAAQFALKDRQQTPELVIVNPPRRGIGKDLAEFLNQLNIPYLIYSSCNAESMVKDFAYLTHYQLHRVQLFDMFPHTTHYETVTLLIRK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
Putative 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: ERA_ALKMQ
Sequence: MSYKSGFVTIIGRPNVGKSTLMNQIIGEKIAIMSDKPQTTRNKIQSVYSQEDFQIVFLDTPGIHKPKHKLGEYMVKVARDTLKEVDVVLFLVDEGQKIGPGDRFIMEQLKDIKTPMFLIINKIDKMNQEILNEVCGLFEETGLFQRIIPISALEGANIDTLIKQIVSFLPEGPQYFPSDMITDQPERLLVAEIVREKLLHYLDQEIPHGIAVETSMMKQRPNQDIVDIQATIYCEKKSHKGIIIGKGGRKLKGVGKSARQDIEKLLGSKVFLELWVKVNEDWRNQSRILKSLGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: CSK2C_YEAST
Sequence: MGSRSENVGTVTREGSRVEQDDVLMDDDSDSSEYVDMWIDLFLGRKGHEYFCDVDPEYITDRFNLMNLQKTVSKFSYVVQYIVDDLDDSILENMTHARLEQLESDSRKLYGLIHARYIITIKGLQKMYAKYKEADFGRCPRVYCNLQQLLPVGLHDIPGIDCVKLYCPSCEDLYIPKSSRHSSIDGAYFGTSFPGMFLQAFPDMVPKHPTKRYVPKIFGFELHKQAQLTRWQELQRLKLVEKLESKDVDLTKSGGFKT
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2 (By similarity).  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).
What are the official names of this protein?
Casein kinase II subunit beta', CK II beta'.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: NPL41_CAEEL
Sequence: MVLEVPQTERVNDVDVFLSTQDGQIQRPKGPNCRHPVRQKCTNCLPVDPFDEEYLKEKDIKHMSFHAHVRKLLGSQGKGTTLKKPLENFRCSLKPNCDAHKPFPKGICTKCKPQVVTLNRQKFRHVDNIQIENQELVNQFLDYWRLSGHQRVGFLIGQYQPHLEVPLGIKATVAAIYEPPQHCREDGIEFLEDKNQKTIDNLLEMLGLQRVGWIFTDCWTANSAEGTVHYTRHKDSFFLSAEECITAAMLQNQHPNITEYSMDRHYGSKFVTVVASGDESMHVNFHGYQVSNQCAAMVEADILCPTLYTPELAYVRETPLSEEHYITDVQFSMKNEYGAEVMKNGRPLPVEYLLVDVPAGMPKEPHYTFHVGTSNKSKSAKFNVENRQAIGQLQGGANLIQYSSEFSKNQFLEQATNFHFLLYLVTNDQVQISDEWMKRLCDAVKAQDRGTAMEWAQECEDWHQLMALAHANGGSGNDVSDIPVIPNGDPFSGSSSGGSGGAVWNCGHCTFQNEAARQDCSMCGLPAAD
What is the function of this protein?
In association with ufd-1 and ATPase cdc-48. 1 and/or cdc-48. 2, involved in the cytoplasmic elimination of misfolded proteins exported from the ER (PubMed:16647269, PubMed:22768338).  This pathway, known as ERAD, prevents the activation of the unfolded protein response (UPR) caused by the accumulation of misfolded proteins in the ER (PubMed:16647269, PubMed:22768338).  During S phase and in association with ufd-1, cdc-48. 1 and/or cdc-48. 2 and ubxn-3, ensures the degradation of DNA licensing factor cdt-1 after the initiation of DNA replication and thus the disassembly of the DNA replication CGM helicase complex by promoting the dissociation from chromatin of several of its components including cdc-45 and sld-5 (PubMed:18728180, PubMed:21981920, PubMed:26842564, PubMed:28368371).  Regulates ubxn-3 nuclear localization during S phase (PubMed:26842564).
What are the official names of this protein?
Nuclear protein localization protein 4 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm during mitosis. Nuclear localization upon nuclear membrane re-assembly is cdc- 48-dependent.
Protein: NUOHI_NOCFA
Sequence: MPDLSLFGHDPFWLVVAKSVFLFVYIILIPLVAVLAERKVVARMQMRVGPNRVGPFGSLQSIADGVKMAFKEDLVPAIVDKPIYLLAPVVSVIPAFMAFAVIPLGGEVSVAGNTTALQLTDMPVGVLYILAITSIGVYGIVLAGWASGSTYPLLGGLRSTAQVISYEIAMALCFAAVFLHAGTMATSGIVGAQHPTWFVFLLLPSFLIYCVSMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMFMLAEYVNMGTVSALATTLFLGGWSAPWPFNLIPGADAGWWGLLWFTAKVWTFMFVFVWLRGTLPRLRYDQFMRLGWQLLIPVSLLWVMLVATARLLRADGHAWATGAQVVVGVALTAAMIGLFLRAGRRPAAPPEPEPEPSGEAVFLGFPTPPVPADAHRVDNPKGGLLEPLAGFAVTAATMFKKPNTEFYPEQKVPTAPRYHGRHQLNRHPDGLEKCIGCELCAWACPADAIYVEGADNTEDERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTNDYELTDDNRADLIYEKDRLLAPLAPGMVAPPPAMAPGTTEADYYLGAVTGGAPAAEQPAPAGAKGGAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunits H/I, NADH dehydrogenase I subunits H/I, NDH-1 subunit H/I.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCAPR_DROME
Sequence: MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLIQGHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAGFGAAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSERV
What is the function of this protein?
Binds to the cardioactive peptide (CCAP), which is a neuropeptide.
What are the official names of this protein?
Cardioacceleratory peptide receptor, Crustacean cardioactive peptide receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein: MYBP_MAIZE
Sequence: MGRTPCCEKVGLKRGRWTAEEDQLLANYIAEHGEGSWRSLPKNAGLLRCGKSCRLRWINYLRADVKRGNISKEEEDIIIKLHATLGNRWSLIASHLPGRTDNEIKNYWNSHLSRQIHTYRRKYTAGPDDTAIAIDMSKLQSADRRRGGRTPGRPPKASASRTKQADADQPGGEAKGPAAAASSPRHSDVVNPGPNQPNSSSGSTGTAEEEGPSSEDASGPWVLEPIELGDLVWGEADSEMDALMPIGPGGTTRLPSKGLARSAARPRWTTCSTWTGMASRPICGAGRSRTSTARSCGRPPSRWKLLLLLLLRRRPAPRTIASWRRSRLGSCPTRSDGSGHRTDQTDQIIGSRVLARSLPSRGSWFRWPNNWEKNSTARAVKPPPCAPDVDACRVELLRI
What is the function of this protein?
Transcription factor postulated to regulate the biosynthetic pathway of a flavonoid-derived pigment in certain floral tissues.
What are the official names of this protein?
Myb-related protein P.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTH_SALHS
Sequence: MNTMTLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVNDIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMVLKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGEGKARWQGEWLPAQTALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFASAVVCGALTTEAVLGSRRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHKVQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFADAGEVISGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGIIAVEWLAACQGIDLREGLTSSPLLEQARQTLREQVAHYTQDRFFAPDIECATALLAQGALQRLVPDFM
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSH3_PHANO
Sequence: MAPKSSQSSQGLSQRSKQQTISSFFTPKPSQTPKAPPKPAALAVPNGADQDDDDDEDEDIAPPRQLTPARKRSIDEQHEDEEAGRSSPPKRVRVANDEPRPSLGNASATTLNAAKPPKITERTSKFLFSSSPVVRDETDAKDDAAATQKLREKLHEKFVKKLGRPDSFAELRRRNKVISEDNGNGEEGEGEEDEEEEEPAPKPTKGRKGAATKKTSKLTPMELQYLDIKRKHMDTVIVMEVGYKFKFFGEDARTASKELGIVCIPGKFRYDEHPSEAHYDRFASASFPVHRLQVHVKRLVKANHKVGVVRQLETAALKAAGNNRNTPFVRKLTNLYTKGTYVDDIEGLETPTAGAQATGYLLCVTETNAKGWGTDEKVQVGLVAVQPATGDIIYDDFEDGFMRSEIETRLLHIAPAEFLIVGDLSKATDKLIHHLSASKTNVFGDRSRVERVEKPKTMAAQAYSHISNFYADKMKSSQEGGSEQGAILDKVHQLSEHVTICLSAMITYLSDYALEHVFDLTKYFQPFSARSYMLLNGNTLSSLEIYQNQTDYTSKGSLFWTMDRTKTRFGQRLLRKWVGRPLIDKERLEERIAAVEELKEGEHTIAVDKVKFLLGKIKTDLEKVLIRIYYKKCSRPELLAALQILQDIASQYLSAKTPEQSGFSSILLSEAVSNVPKIYEDVNSFLEKINAKAAKDDDKYGFFREEFEAEDINDLKLSIASVEDDLNTHRKDAAAKLGKTKVDYVTVAGIEYLIEVKRKSVEEKKVPASWQQISATKTTLRFHTPEVKRMLQERDQYKESLAAACDTAFKRLLDDIAAKYQSLRDCVSSLATLDALLSLATLANQPGYVKPTFVETTELDIVGGRHPMVEQLLLDAYVPNDVHLSGDATRALLVTGPNMGGKSSYVRSAALIAIMGQIGSYVPAESAKLGMLDAVFTRMGALDNMLKGESTFMVELNETADILRSATSRSLIILDELGRGTSTFDGVAIAEAVLDYVIRDVGALTLFITHYQHLARLQDRFNGELKNVHMSFEERDGGKEVVFLYEVAEGTSHRSYGLNVARLAKVPEKVIETAEVKSSELEESMGISRVANMARMVKGLLEDGGEEGLERLIEGIEQL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  MSH3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MSH3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA_GUITH
Sequence: MVNIRPDEISSIIRQQIDKYDQAIQVSNVGTVLQIGDGIARVYGLDQVMAGELLEFEDKTIGIALNLESDNVGVVLMGEGRGILEGSSVKATGKIAQVPVGKSYLGRVVNALGTPIDGKGDINCSETRLIESIAPGIISRKSVCEPIQTGITAIDSMIPIGRGQRELIIGDRQTGKSSVAIDTIINQKGEDVVCVYVAVGQKAATVASIVTTLEEKGALDYTCIVAANADDPATLQYIAPYTGAAIAEYFMYNGQATLVIYDDLSKQASAYREMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDKLGGGSMTALPVIETQAGDVSAYIPTNVISITDGQIFLSGDLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFSQFASDLDQATRNQLARGQRLREILKQPQNSPISVEEQVAIIYTGINGYLDDIAVDKVRRFVTNLRTNLKNSKPQYAEIIRNTKTFNSDAENLLKSAIADTKQSFV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL35_RICPR
Sequence: MPKLKTKSAVKKRFKFTATGKVIASQAGKKHFMRRRTKAQIRNLRGTTILCPQDGHNIKKYFLPYGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FABZ_HISS2
Sequence: MTVTTERIARIIESKEIMTLLPHRYPFLLVDRVTDYEEGKWLTAIKNVSVNEPCFTGHFPDQPILPGVLILEALAQAMGILAFKTHELSNKELFYFAGVDEARFKRPILPGDQMMLKVEVIRERRGITAFTGVASVNGEVACEAKLMCARR
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_LASSJ
Sequence: MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNNSSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPRVVL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CARA_HELPJ
Sequence: MVSLYLENGLFLQAQSFGASGTQVGELVFNTSMSGYQEVISDPSYKGQFVVFSMPEIGVVGANPKDDESFFSCAGVLARHYNEFFSNSRADSSLSTYLKKRGVLGISGVDTRSLIKTLRHHGCLMMIASTIEHDRNKLEEVLKNAPKISHSPLVSSVSTPKIITHQRATFDFNTLDYKPFDEKIPHKIIAVLDFGAKGNILNELQNVGLKALIYPHHTKANELIKAYEKKEISGIFLSNGPGDPLSLQQEIGEIKRLINAKIPMFGICLGHQLLSIAQGYPTYKLKFGHHGSNHPVKNLETNAVEITAQNHNYCVPEEIEEIATITHRNLFDNTIEGVRYKNAPIISVQHHPESSPGPKESHYIFKEFVGLLEGF
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: NRDR_SHEB8
Sequence: MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQGGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RK23_WHEAT
Sequence: MDGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPLLDREKN
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UEVLD_DANRE
Sequence: MDVNSEPVKKVLSKYKFRDVAVEELQKVYRVYPDMKIMAGTYTSSDSLQKDLLKLVGNIPVVYQGRSYNIPILLWLLDSFPFTPPICYLRPTSSMVIREGKHVDSKGRIHLPALHNWDHPKSSVNALLAEMIGKFEEEPPLGTKSSAHGDTPSNLLDYVSNLTITEGGNRPDQEVKVSVIGGGDLGIAAVLSIMAKSCVDKLVLIDIPENSTKGGTMDLEIFSLPKVEVSKDLSASAGSKVLVITANAWSDEQSYLSVVQTNVDMYRGIIPRLAQLSPNAVLVIASQPVDVMTHVAWRQSHLLPTQVIGVGCNLDSQRLSHIINISLVANNTGKQAWVIGELSENKVAVWGNMGPGTDQLQALTPVSNSTKPLMDRAFEMIKGRGQRSWSVGLSIADITHSIVTNQKKVHSVTTLAEGWGGIGSKVFLSLPCILGETGSTRLPGVALGSEDEMKLRESVACQVNLFMQLRL
What is the function of this protein?
Possible negative regulator of polyubiquitination.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 3, UEV-3, EV and lactate/malate dehydrogenase domain-containing protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LDH/MDH superfamily.
Protein: HBB_URSTH
Sequence: VHLTGEEKSLVTGLWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSADAIMNNPKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: REG6_PYRAB
Sequence: MRVSLDEIDRRIIKILQKDGKAPLREISKITGLAESTIHERIKKLRESGVIRKFTAIVNPEALGYSMLAFILIKVKAGKYAEVASNLVKYEEIMEVYETTGDYDMVVKIRTKNSEELNSFLDVIGSIPGVEGTHTMIVLKTHKETTELPIK
What is the function of this protein?
DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes.
What are the official names of this protein?
HTH-type transcriptional regulator FL11, Feast/famine regulatory protein FL11, FFRP FL11.
Protein: NAGZ_HAEI8
Sequence: MSTLLIDLKGKELEQEEVELLSHPLVAGLILFTRNFEDREQIQELIRSVRQRVKKPLLITVDQEGGRVQRFRDGFTMLPSMQAFQETLSATEQVSFAKEAGWQMAAEMIALDIDLSFAPVLDLGHECRAIGDRSFSSDVKSAVNLAINFIDGMHQAGMASTGKHFPGHGHVLADSHLETPYDDRAKDEIFGYDLQPFQQLISQNKLDAIMPAHVIYGQCDSQPASGSEYWLKEILRKKLNFQGTIFSDDLGMKGAGVMGNFVERSKKALNAGCDLLLLCNEREGVIQVLDNLKLTENEPHFMARQARLKNLFKRSVIEWNDLVLDQRWKLNHRNLADIQSRWLDIQAAKND
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.