PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_ACTPJ
Sequence: MTTATGTKPKKMEAFKMERGVKYRDAAKTSVIQVRNIDPDQELLPKPSWMKIKLPAASAKIDSIKHGMRRHGLHSVCEEASCPNLHECFNHGTATFMIMGAICTRRCPFCDVAHGKPLPLDLEEPRKVAETVQDMKLKYVVITSVDRDDLADRGAAHFAATVREIKALNPECKVEILVPDFRGRVEQAVEILKQNPPDVFNHNLENVPRLYREVRPGADYKWSLELLKIFKQEFPNIPTKSGLMVGLGETNEEILEVMQDLRDHGVTMLTIGQYLQPSRHHLKVERYVPPEEFDMFRSEAERMGFEHAACGPFVRSSYHADLQAKGELVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLS1_STAAR
Sequence: MQFSFSNDLGTLFTIILAIGFIINLVLAFIIIFLERNRRTASSTWAWLFVLFVLPLIGFILYLFFGRTVSARKLNKNNGNVLTDFDGLLKQQIESFDKGNYGTDNKQVQKHHDLVRMLLMDQDGFLTENNKVDHFIDGNDLYDQVLKDIKNAKEYIHLEYYTFALDGLGKRILHALEEKLKQGLEVKILYDDVGSKNVKMANFDHFKSLGGEVEAFFASKLPLLNFRMNNRNHRKIIIIDGQLGYVGGFNIGDEYLGLGKLGYWRDTHLRIQGDAVDALQLRFILDWNSQAHRPQFEYDVKYFPKKNGPLGNSPIQIAASGPASDWHQIEYGYTKMIMSAKKSVYLQSPYFIPDNSYINAIKIAAKSGVDVHLMIPCKPDHPLVYWATFSNASDLLSSGVKIYTYENGFIHSKMCLIDDEIVSVGTANMDFRSFELNFEVNAFVYDENLAKDLRVAYEHDITKSKQLTEESYANRPLSVKFKESLAKLVSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase 1, CL synthase 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_YERPB
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_THIDA
Sequence: MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLLYGFGSEVERAAFRELLKVSGIGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKTAERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYNERETAATVRELPAGLAVGEAIRQALRALSRA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: 3602L_ASFP4
Sequence: MSTPSSLQALVKKVLATQHISKEHYFILKYCGLWWHGAPIMLSTNENNQLMIKSAIFKDGLDLNLALMKAVQENNYDLIELFTEWGADITSSLITVNTEHTWNFCRELGAKILNEMDIVHIFYKIHRIKTSSNIILCHKLLSNKPLFQNIEGLKIIICCFLEKIPINFILNEITFNEMLTRYWYSMAIQYNLTEAIQYFYQRYSHFKDWRLICGLSFNNVSDLHDHIKKVDMNIDEMMYLACMRDSNFLTIFYCFVLGADINRAMVTAVKKFYTNNLFFCIDLGANAFEESLELAKQKNNDILAELLSFKDYYSSNASLLSLKTTDPEKINALLKNYKSKNIMRYKKLSRK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-2L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: LUC6_FUSSX
Sequence: MHQIFPSTFFNFEFLRLLGTAPYLGAETGECLATAARIKDGDPESWYQAWYEQAQKALALADEAKAVGDGPGAAWGYIRASNYFRASEFLLHCTPEDPRILSSAVASADAFDKGWILLDGSVRKVEIPYEGGNTLPGRLYLPAPHHQVSGKIPVVVQTGGFDSTQEELYYYGAAGALPRGYAVFSFDGPGQGLSLRKDKLYLRPDWEHVTSKVLDHVIGELAPVHNLDVDRLAVFGASLGGYLSLRAAADPRVKAVVSCDGPLDLFDITRSRMPPWFINGWLSGWLSDGFFNWVIDRLASVNFQLAWEFGHSKWVYGVKTPADVMRTMQKFSLKDGYLSKIKCPTLITGAADSFYFTPQQNAHPIFDSLSALGPAEKHLWIGKDVEGGGLQAKIGALALMHHKMFAWLDETFGIRRDEL
What is the function of this protein?
Hydrolase; part of the gene cluster that mediates the biosynthesis of the mycotoxin lucilactaene and the lucilactaene-related compound NG-391 that act as cell cycle inhibitors with potent growth inhibitory activity against malarial parasites, moderate growth inhibitory activity against cancer cells, and no activity against bacteria and fungi (PubMed:32043422, PubMed:35484225).  Within the pathway, LUC6 may catalyze the 2-pyrrolidone ring formation to form prelucilactaene C from prelucilactaene B, followed by C-15 hydroxylation by the same enzyme to give prelucilactaene D, epoxydation to yield prelucilactaene E, and finally cyclization to yield prelucilactaene F (Probable).  The pathway begins with the hybrid PKS-NRPS synthetase LUC5 which is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate prelucilactaene B.  Both the cytochrome P450 monooxygenase LUC2 and the hydrolase LUC6 function in parallel in modification of prelucilactaene B.  LUC6 may catalyze the 2-pyrrolidone ring formation to form prelucilactaene C from prelucilactaene B, followed by C-15 hydroxylation by the same enzyme to give prelucilactaene D, which is then converted to prelucilactaene E by epoxidation, and finally to prelucilactaene F by cyclization.  Prelucilactane D, prelucilactaene E, and prelucilactaene F can be converted to dihydrolucilactaene, NG391, and lucilactaene, respectively, via C-20 methyl group hydroxylation by the cytochrome P450 monooxygenase LUC2.  However, LUC2, unlike FUS8 in fusarin C biosynthesis, is not enough for the full oxidation of the C-20 methyl group into carboxylic acid, which is a prerequisite for the final methylation step.  The aldehyde dehydrogenase LUC3 is involved in the biosynthesis by further oxidation of the C-20 alcoholic analog prelucilactaene G into a carboxylic derivative.  This unidentified carboxylic derivative may be converted to demethyllucilactaene.  As the last step, the methyltransferase LUC1 methylates the hydroxyl group at C-21 of demethyllucilactaene to generate lucilactaene (Probable).
What are the official names of this protein?
Hydrolase LUC6, Lucilactaene biosynthesis cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. FUS2 hydrolase family.
Protein: TRPA_METCA
Sequence: MSRLTSTFQVLRHANRKALIPFITAGDPEPGFTVPVMHAMVEAGADVIELGVPFSDPMADGPVIQKASERALVHHMSLGKTLDLVAEFRRADRTTPIVLMGYLNPVECMGYQRFVDRAKDAGVDGVLTVDMPPEEAGEFVPMLHRAGLDPIFLLAPNSSDARVQRMAALGRGYLYYVSLKGVTGASHLDLAEVESRIAHIRSLTDLPIGVGFGVKNAETAAAIGRFADAVVVGSALVEKIAAAQDRPEQARKDIVDLLAVMRRALDA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CSTF3_PONAB
Sequence: MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSTLIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIITGGAPELAVEGNGPVESNAVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR
What is the function of this protein?
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.
What are the official names of this protein?
Cleavage stimulation factor subunit 3, CF-1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, CSTF 77 kDa subunit, CstF-77.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAPK_BACSU
Sequence: MSKIASEVVATTLNDWYIAIKKQKVDESIKYYSEIKKLFDEMEEDQEVLAYYSLLEERHKMLLHSSRGEPLQKHTYFTEDNQNFITKTNDKLEYNFYLFEAMYEAYNKNYDRAINLYGLAEKKLAEIPDEIEAAEFYSKVSYLYTLVKQSIVAQHYIKNAISIYKRHPDYKCKLATSTMIAAANYADMKRFEEAEQYYLEAIDIAKETKDEFLKAQLFHNLSIVYSDWNKPDKCIESLEKAIGNESWLHSIYYINSLFMMIKELFKIDEKMKAINFYNKAQERLILMENKVYEAKISILYNLYCGELKNNFNNCISNIEFLKQQNELESVDELSYIAAKRFESIGAFEEATSFFNAKIWAEQKMNQVEGIL
What is the function of this protein?
Involved in the regulation of genetic competence development (PubMed:16816200).  Inhibits the activity of ComA, a transcriptional factor that regulates the development of genetic competence (PubMed:16816200).  Likely affects the activity of additional regulators, in particular Spo0A (PubMed:16816200).
What are the official names of this protein?
Regulatory protein RapK.
What is the protein family that this protein belongs to?
Belongs to the Rap family.
Protein: RK16_CYACA
Sequence: MLSPKKTKYRKFHRGRLKGHATKGSALAFGRYGIQALTSSWITSRQIESVRRVIVRHLKRGGKLWIRIFPDKAVTAKPLETRMGSGKGSPEHWIAVVKSGHILFEIDGVSLELAKEAVKLAIYKLPIKCKFLSNDEFAKD
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TATA_POLNS
Sequence: MGSFSIWHWLIVLVIVMLVFGTKKLRNIGQDLGGAVKGFKDGMKTFEEPKEQIQQSSATAEKTVDVQAKDVNK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ADDA_LIMRJ
Sequence: MAGFKPTPAQSKAINDRGENILVSASAGSGKTAVLVNRTIELIKEGQSIDRMLLVTFTDAAAKNMRDKIRAALQKIVQDSANPKDLRDRMSNQINRLAAADISTIHAFCLKLIKRYYYLIDLDPQFRLLTDETERLLLQEDVWHEVSEELYRNAEEKVSGKASFSELVLNFSSDRDDQGLDDLILRLYEIANAQPDPEKWLQKLPDNYDLGSGSLLESNFYQQQLKPLVIEKLNQFIQDYRELVTRASDNGLDQAAEVIKSDEELMHQLLSSLGGITVSDVCQMMAQQKFGSFRGRPAADDPRIDVFKDIQKQRNQLKKQWEQMVSTYLGKQEAQEPIAKEELLTELTTFSDQFTDLLSKATESQLDAKTVDSLQKDQQMMQELLDLLQPPTWNTIRDLFANAKFARMGGKPKDDELAEEVYKSLGSARTGIKKQFDQLVDRFFNYREDQFRLISTHAQELLRELSAVTINFRRRYQQTKLNRHVLEFSDLEHYAYAILTPPDDQPNWQTLVKDLQNHYQEIMIDEYQDTNRLQESILMKLTSPERKNLFMVGDVKQSIYRFREADPTLFLGKYQNYRQGSDGEAIVLGENFRSMTNVTSFTNILFEQLMDREVGEIDYDEDAHLKYAATYYEENQDNKVHPTEVLLYDANALDPEKEDVEHEDDKLAGEFRMIGMRIKQMVENQELIFHPEDGQMHPIQYGDIVLLERTKAINNSLMEEFNKLNIPLTVHDVESYFQATEVRVMMSLLKIIDNPQQDIPLVAVLRSPIVGLTNQELAFIRLQNRSVDYYAALQTFMSNYQRKALRHQSLLTSEQVNALYEKADHFLGLLRVFRQTAQQQTLVDLIWQIYDQTGYLDYVGAMPGGHQRQANLHALYQRAHSYEQSSFKGLYQFIRFIEKMQEHDKDLGVAPTQLTANTVNVMTIHGSKGLQFPVVFLIDATHGFNKGAARENAVVDAVAGVGIRYMDDQRVIYDTPQRQAVIEEIQRGERAEDLRVLYVALTRAEQRLVITGSFNEEMRTQSLAGSWQRWQKAYQSKNLLIGPQPRITANSFMDWVGLALARYPEFNAQQLSRGNVTLEESTLADTKVTGLAADPHFTAKTYTALDVSDGLAKIGQNASANVTEKNNTVATDASEQKIEQILRYRYPHLVATKTTAYQSVTDVKRVFEDPDTRDMARWDYDQQQKVKTQGIYLNNNFDVPAFIQQTTHEPVATEIGTATHLVFQKLPLDEGLINVEFVDQEIQKLVGEKLINPVVAARINREGIVAFYQTAVGQKILKHPADYHREVPFSMIMNGHELFKGVNVSDDERILIHGIIDGYLRTDEGIILVDYKNDHLNKDYRDFDLARIKDRYRGQLELYKEALNLMEGIPVVQMGLYLLELGEFVLFTKEGD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: LIPA_DEIGD
Sequence: MTQQAKEPKFIKNGIYRKDAVPVRDKKPEWLKVTIPTGQVYGEVRKIVKEHRLHTVCEEAMCPNIGECWSRGTATFMLMGHICTRACRFCAVDTGNPMGKLDLEEPAHVAESVRLMGLKYVVLTSVDRDDLPDGGAYHFAKTVTAIKRENPGTRVEALTPDFGGNPHCVDLVLESGVDVYAQNLETVRRLTHPVRDIRASYERTLGVLKHAKQSRPDVITKTSIMLGLGETREELREAMLDCRAHGVDVITFGQYLRPTMHHLPVERYVSPAEFDEIREEGLSLGFLEVVAGPLVRSSYKAEQIVMDKPGNLPEHLAHLEGKEQLSLI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_PEDPA
Sequence: MSLPKKLEEMQVEEASKLAQNLREILDRWSKLYYTKDAPEVEDYEYDEKYADLVALEEAFPEIITQDSITQRVGGEILEGFTKVTHTEPMLSMGDVFSRDELVEFDNRIQKNVGHPVDYNVELKIDGLAISLIYQDGELIQGSTRGDGNIGEDITKNLKTIKSVPQKLTRPLSIEVRGECFMPKASFAKLNAQQLEDGKPVFANPRNAAAGSLRQLNTNVTKKRDLDTFIYTVVDSNQLGAKTQHQAIQMMAELGFNTNPTQEVCANLDEVWDYIAKYEGQREDLPYGIDGIVLKVNDLSLQQELGHTVKIPRWEIAYKFPPEEAATVVRDIEWTVGRTGVVTPTAVMDPVQLAGTTVSRATLNNVDQLTAKDVHIGDTVLLHKAGDIIPEITRVVLEKRPVGISELDIPTHCPSCGKELVHLNGEVALRCINPDCPAQIVARLEHFGSRNAMNIMGLGPKQIQQLYAKNFIHHFDDLYKLTSEELSQLDGFKEKRVNNLLEAIDNSRKNSLERLINGLGIQGVGTKMARTLAEKFGTMDNLMQTTIEEFDAVDTIGETLANNLATFFQSDVAQNMIDELKAVGVNMEYLGVKPAESPDGYYKGKKVVLTGKLEQYTRNELKERLISLGADVAGSVSKKTDILIAGADAGSKLTKAQALGIEILDETEAIAKFEQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YQGF_PROM4
Sequence: MLPAISKSVLSLDVGKRRIGIAGCDPLGITITQLEAIKRTTFNNEATQLRQLCDLRDVRGIIIGLPLSDLGKETKQSSYCYTYGINIAKELNLPLAWVNEHSSTWEAGQRFKLQNDRSGKLDSAAAALLLEQWLTEGPELEFLKN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_DESVH
Sequence: MKPSREELKKRLTPLQYDVTQEEGTEPPFRNEYWDEKREGLYVDIVSGEPLFSSRDKYDSGTGWPSFTRPVDPQGIVERVDRKLFTTRTEVRSRNGDSHLGHVFPDGPQPTGLRYCINSAALRFVPVEDLEQQGYGHLLHLFQ
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RS16_CORK4
Sequence: MAVKIKLQRLGKIRTPHYRVIVADSRTRRSGRAIENLGIYEPKADPSVIRIDSDRVQYWLGVGAQPTEPVLALLKVTGDWQKFKGLPGAEGTLKAQPEKKSKLDLFNEALAEANNGPTLEAITEKRKAAKKAAEEAAAKEAEAEEAAEDKAEEESAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FADJ_ECO27
Sequence: MEMASAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIKQIRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEVLARQGQQLMAEIHALPIPVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQAVKLGLVDDVVPHSILLEAAVELAKQDRPSSRPLPVRERILAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRNIFFASSEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLPVRIKDINPRGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYCGFAHRDLIIEAVFENLELKQQMVAEVEQNCATHTIFASNTSSLPIGDIAAHAARPEQVIGLHFFSPVEKMPLVEIIPHASTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIRMLTEGERIEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIMPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVMLMLNEAVRCLDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCDRLVEMSERGESFWKTTATDLQ
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_ACTSZ
Sequence: MKTWKDVIGNEKTQPYFQHILAQVHQARASGKVVYPPQADIFNAFKLTEFDQVKVVLLGQDPYHGPNQAHGLAFSVKPPVAPPPSLMNMYKELSNEYPDFHMPNHGSLEQWAQQGVLLLNTVLTVERGQAHSHADFGWETFTDHVIHALNEQREHLVFLLWGSHAQKKGQFIDRSKHCVLTAPHPSPLSAHRGFFGCGHFTQTNDYLRRHHISEINWQLDNI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_TATCI
Sequence: MNIRRRRRLLVVVAILVGLGLATGLVMYALRSNIDLFYTPSEILNGRGPEHKDIPHPGQRLRIGGMVMPGSVKRDPKSLAVEFKLYDANGVVSVSYVGILPDLFREGQGIVAEGVLEDGNLSGDQVLAKHDEKYTPPEIEDAMKQNHKGLLNVSEPTR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: KDPB_ENTFA
Sequence: MKKIYQWAVGQSFKKLDPRQQVKNPVMFVVYLGALITTILCFYPMGIPLWFNISITIFLWLTLLFANFAEAVAEGRGKAQADSLKQAKKEVMTYKINSLEDIKEENFIELQSSDLKRNDLVYVRAGEQIPADGDVIEGAASVDESAITGESAPVIRESGGDRSAVTGGTTVVSDYLVIRVTSENGQSFLDKMIAMVEGTQRKKTPNEIGLQIFLITLTIIFLTVSITLVPFTDFSSQLSGKGEALSLVIVIALLICLAPTTIGALISSIGIAGMSRLTKENVIAMSGRAIEAAGDVDVLLLDKTGTITLGNRRASDFLPVHGVSEEQLADAAQLSSLADETAEGRSIVILAKERFNLREREFQQSEVKFIDFSAKTRMSGIDYRGDVIRKGAADTMKKYVQSKGEDYPSECDKIVDKIARAGGTPLVVIKNNRVMGVVYLKDIVKNGVKEKFADMRKMGIKTIMITGDNPLTAAAIAAEAGVDDFLAEATPENKMNLIREYQEKGHLVAMTGDGTNDAPALAQADVAMAMNTGTQAAKEAGNMIDLDSSPTKLLQVVQIGKQLLMTRGALTTFSIANDIAKYFAVIPVLFYSIYPQLDRLNIMGLGSPLTAILSAVIYNAVVIVALIPLALKGVRYQEKPASQILSHNLLIYGLGGIIAPFIFIKIIDLILSLIIL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIC_CLOB1
Sequence: MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: YL264_MIMIV
Sequence: MNRNIRRVRREVDSYIPSNNVNVETEGYLIRRIPKKCKPKVTSTIAQRVSQLENEVAEINVALAEHVNELNSQEKRIDKLEKTVKKKKSNCSDDSECSECSECSERSCCSKCNSNKCCCNNTCGVFPNSVEAFSYYGPISGNCGPFPGGNCGPFPGGPCGPFAGGNCGPFSGGSCGPFPGGPCGPIPGGNCGPIPGGPCGPISGGPCGPISGGSCGPALPYSAAVDGYEYFQNGPMMSCPPIGPMGPNGFVEEQFVGGNGPFIGGGGFIGPNNGFVEESWGNCNDCRRGKCKKHKNRRSKSDNSDLSEYSSSNSDDSECTDSDGSSCSTDGSPDCTESENTESHRSHGKKKHRFVNKKRNTCNNSDNKDNSRINMNICDLLKLFGDKCPIKIDPNEECKQVPNEFIQIKCCQEQICCQNSCCANKNSCCTDNCCPKTKCCEKDDTNSYTIEWQKSPDCCKEIDYCEKPFSCETNYCGNSYETDYCPIYIKPDSINSNNYTNSSEKYQYNHYDSDNCSDNYSDNYSDNDSEKVYNINLDATNINTDPNYNHNFNNNHNFNNNFTNNRMTDYSTDYISHNFNPGNNQYSQQISHEQNINQQQSQNSENLLDNNEYGDYENYYNMLRGDQNIFPVNNSSNFNQYESTDISNNQNFNSQIVDSIIDTNHNKDSIQVEFSNNNDKTHHEKNECHCHEHSQPCKTTSIVPFGTPIVDCNNCRNEECITIIQTDSSCSSNKVPIIQPIEPETKTMSIIDTAIANIDTCTDLTLINQPKGISTDAAILWAAKIGNLNMNQGMKVTTDSNNNIIVAGFYRADVTPEPSNDDVPPTVIYDSKGCGVKNITASGIEEIFIVKYDMYGNFLWFAKIESTFTDFTVSIAVDTEDNVIVTGSFTDSAVNIYDSTSQLVKHIPQPIPEPSAEITQSFIVKYSPAGIYQWTAVLFTSGIAVIKSVTTDPNNNIYITGYYGGQTLTFQNSDGTDSYSLGANSLTNVFVAAYNYLGFVLWVTMCGNIGNTVSEQGYNEGLDIKYSPDQTIVVSGYYNTNPLIIYDGPDGLTPSGISLTNVNNTNINITGNDINTTPDIFLIKFRLNGTALWATKISGTITQFNTSVWASEFSGISNQFYTTIAIDPDANIIITGTYNQGPVQIFNTPSGTILSTINLIITGTISTYIIKYGPRGNAIWATRISGALSQVSNGIATDSDSNIIVSGYFSAPVTVFYSSDGTTPFTLENVSEISAFTVKYDRCGNALWAVKQENNGITQALNVAVDNNDSVVIVGTFNQAPINFYNSNKQMAKCIINDSSYDGYVAKYADFVQSLVLLPGCKQKDIAINESCYKRANTLVTYKAGTISNSVSNCLRGFLMTRANSSIKLLPNGNNWLVDYSNNILFIYP
What are the official names of this protein?
Uncharacterized WD repeat-containing protein L264.
What are the subcellular locations of this protein?
Virion.