PharMolix/UniProtQA huggingface dataset:
Protein: IF3_BACSU
Sequence: MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKEKEARKNQKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLMLAPKNEKQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMBT1_MOUSE
Sequence: MSGEQQLDADLGSGVEVEEFSWEDYLEETGSTTVPYASFKHVDIRLQNGFAPGMKLEVALKNDPETYWVATIITACEQLLLLRYEGYGEDRKADFWCDIRKAGLYPIGWCQQNKKTLEAPEGIRDKVSDWNAFLQQTLIGACGPPVSLLEGLRNGRNPLDLIAPGSKLECQDFRDSLSTWLVTVVENIGGRLKLRYEGLESRDGFEHWLYYLDPFLHHIGWAAQQGCDLQPPLAIKHLKSEADWQEILAKVKEEEPLPSYLFKDKQVIGTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEMDDLRPEDHTRRSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSISEHQFKENMKLEAVNPLFPEEVCIATVTAVRGSYLWLQLEGSKKPVPEFIVSAESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKNQLNSTHSVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKSSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEEDADDGDEDSLTEGSTSEQQEELQEESEVSEKKSSSSSPTQSETPTPLPPDTQTNKRDAQTSSVSDDENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN
What is the function of this protein?
Histone-binding protein, which is part of various corepressor complexes.  Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription.  Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1.  Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes.  Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.
What are the official names of this protein?
Scm-like with four MBT domains protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOE2_BOVIN
Sequence: MAPERLRSRALSAFKLRGLMLRGEAVKYLTEALQSINEIELEDALEKIIDAVEKQPLSSNMIERSVVEAAVQECSQSVDETIDHIFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFGTARDKAELFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTSKIGDVIVLGMITQLKEGKFFLEDPTGTIQLDLSKAQFHSGLYTESCFVLAEGWFEDQVFHVNAFGFPPTEPSSTTRAYYGNTNFFGGPSNTSVKTSAKLKQLEDENKDAMFVFISDVWLDQVEVLEKLHIMFSGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICGYPNIHQSSRFVFVPGPEDPGFGSILPRPPFAESITNEFRQRVPFSVFTTNPCRIQYCTQEIIVFREDLVNKMCRNCVRFPSSNLDIPNHFVKTVLSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVIADKYDPFTLTNTECLCINPGSFPRSGFSFKVFYPSNKVVEDSKLQGF
What is the function of this protein?
Accessory component of the DNA polymerase epsilon complex (By similarity).  Participates in DNA repair and in chromosomal DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase epsilon subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_VIBC1
Sequence: MSNIIKALEEEQMKSDLPKFAPGDTVVVQVKVKEGDRERLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERTFQTHSPIVDSIEVKRRGAVRRAKLYYLRERSGKSARIKEKLAKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL30_RICBR
Sequence: MNNKNLINDVKVTQVKSSIGRKYDQKLTLIGLGLNKINKSVVLKNTDSVQGMLKKVEHLLKIENV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: INP5E_MOUSE
Sequence: MPSKSACLRHTEAPGQLEGRMLQGQPPNTEKKLIPTPGFLPASDSQGSETNPMPPFSIPAKTSNQNPQTKANLITPQPPIRPKLERTLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKSRRATGSEGGSPSLWSDCLSGMISTSLDLLHRDAASGGPPSRLASLHASHTPPAMDLSIASSSLRTANKVDPEHTDYKLRMQTRLVRAHSNLGPSRPRSPLAGDDHSIHSARSFSLLAPIRTKDIRSRSYLEGSLLASGALLGAEELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGIQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYSRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLKQKPEVDVLALLQHDQLTREMKKGSIFRGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKGDICPMKYSSCPGIKTSDHRPVYGLFQVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQRQEALKSQSSSAVCTVS
What is the function of this protein?
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Specific for lipid substrates, inactive towards water soluble inositol phosphates.  Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity) (PubMed:10806194).  Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (PubMed:19668215).
What are the official names of this protein?
Phosphatidylinositol polyphosphate 5-phosphatase type IV, 72 kDa inositol polyphosphate 5-phosphatase, Inositol polyphosphate-5-phosphatase E, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol polyphosphate 5-phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus. Note=Peripheral membrane protein associated with Golgi stacks.
Protein: DXR_SHEWM
Sequence: MQSMVILGATGSIGASTLSVIASNPETYSVYALVANTNVDKMMALCEQYRPKVAHMVDEQAAKSLQERLSPSLKIEVTTGESQLESIVTSSCVDTVMAAIVGAAGLVPTLAAVKAGKRVLLANKESLVMSGRLFIEEMKKSGAQVLPVDSEHNAIFQALPEPVQQEIGFCDLDEAGISHILLTGSGGPFLTSPLSSLPQMTPAQACKHPNWSMGRKISVDSASMMNKGLEYIEARWLFNASAEQLKVVIHPQSVIHSMVQYRDGSVIAQLGNPDMRTPIAHCMSYPQRINSGVEPLDFFKVGQLSFLEPDFTRFPCLALAIDACNQGQEATTILNAANEISVAAFLDNKIKFTDIAKVNETCLSQVAKQALNSIDDILALDVQTRTYASEWVNKI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ARGB_AZOC5
Sequence: MSASIADNVAEAQLQAEVLTKALPHMQRYDDAIVVVKYGGHAMGNDELARHFAQDIVLLEQSGVNPVVVHGGGPQIGAMLEKLGIKSEFAAGLRITDKATIEIVEMVLAGSINKQIVGFINEAGGKAIGLCGKDGNMVRARKATRTIVDPQSHIEEVVDLGFVGEPDTVDTMVLDQILGRELIPVLAPVASAVDGGTYNVNADTFAGAIAGALGAKRLLLLTDVPGVLDKNKQLIPRLTIDECRALIADGTVSGGMIPKVETCIYALEKGVEGVVIMDGKLPHSVLLELLTDHGIGTLITR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_LACP3
Sequence: MTSVIFLGTPEFAVPILEGLIAQHYDILAVMTQPDRKVGRKLRLAASPVKQAAQKHDIPVLQPEKLSGSPELAQAIAMAPDLIVTAAYGQFLPTKFLEAAKIIAVNVHGSLLPKYRGGAPIQYSIMNGDSETGVTIIEMVKKMDAGDMFAQAKLPLTRADDTGTVFAKLSLLGRDLLLETLPKIIAGTATRTPQDPDKVTFSPTITKEQEHLNIHLPAKALDQWIRALRPDVGGYVYLNGQRTKLWAITPLSAGSTLPAGSIVERDKHRLVMVAGQQTTFQVDELQPAGKAKQSIADFLNGPGQQLVSGQQVITDDPE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: AT1A1_CANLF
Sequence: MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVIGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVKGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKSSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRDRYAKIVEIPFNSTNKYQLSIHKNPNTSEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDALQNAYLELGGLGERVLGFRHLFLPDEQFPEGFQFDTDDVNFPVENLCFVGFISMIGPPRAAVPDAVGKCRGAGIKVIMVTGDHPITAKAIAKGAGIISEGNETVEDIAARLNIPVRQVNPRDAKACVVHGSDLKDMTSEQLDGILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDASKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPTHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon. Melanosome.
Protein: WNT11_COTJA
Sequence: MKPSPQFLLAAFLSLILQTGICYGIKWIALSKTPSALALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  May play a role in the formation of dermal structure, both limb and feather buds.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-11.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y1289_ARCFU
Sequence: MKPEEIVEGLLSGNRRALARAITYVENEYPESKEIMRQIFAKTGRAHVVGLTGFPGVGKSTLVSKLTEEFRRRGKKVGIIAIDPGSPFTGGALLGDRLRLDGMDSRKQLWTDPGIFFRSMSSRGRAGGLAAKTGDVVRLLDAFGFDVILVETVGAGQSEVDIIEVADTSVVVMMPETGDEIQVNKAGILEIGDIYVVNKADLGGAEKVERWLRYMLSLDEESVQMLSQMTHADEARVQSGEFFERRKGWNPPVIKTVADRGEGIKELADAIEEHFDYMKKTGLIEKRRRERVKRELFEIVMNDVIKLVKEKTNYRDLLVKLLKGETDPYTAAEQIVEEVIHNAGKG
What is the function of this protein?
May have GTPase activity.  May also bind and hydrolyze ATP.  May function as chaperone (By similarity).
What are the official names of this protein?
Putative GTPase AF_1289.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
Protein: ENV_FLVCA
Sequence: PHQIYNVTWVITNVQTNTQANATSMLGTLTDAYPTLHVDLCDLVGNTWEPIVPDLRGWASYSSSKYGCKTADRKKQQQTYPFYVCPGHAPSLGPKGTHCGGAQDGFCAAWGCETTGEAWWKPTSSWDYITVKRGSSQDNSCEGKCNPLVLQFTQKGRQASWDGPKMWGLRLYRTGYDPIALFTVSRQVSTITPPQAMGPNLVLPDRKPPSRQSQTGSKVATQRPQTNESAPRSIAPTTMGPKRIGTGDRLINLVQGTYLALNATDPNKTKDCWLCLVSRPPYYEGIAILGNYSNQTNPPPSCLSIPQHKLTISEVSGQGLCIGTVPKTHQALCNETQQGHTGAHYLAAPNGTYWACNTGLTPCISMAVLNWTSDFCVLIELWPRVTYHQPEYVYTHFAKAVRFRREPISL
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: PGPI_HUMAN
Sequence: MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQLVVHVGVSGMATTVTLEKCGHNKGYKGLDNCRFCPGSQCCVEDGPESIDSIIDMDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYQSHGRSAFVHVPPLGKPYNADQLGRALRAIIEEMLDLLEQSEGKINYCHKH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyroglutamyl-peptidase 1, 5-oxoprolyl-peptidase, Pyroglutamyl aminopeptidase I, PAP-I, Pyroglutamyl-peptidase I, PGP-I, Pyrrolidone-carboxylate peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_SALPK
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYTAPDVTLEADLQRRDLTINALARDDDGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEYHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREELTKRRIAAVANWKEKRCPNPAS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RRF_MYCTU
Sequence: MIDEALFDAEEKMEKAVAVARDDLSTIRTGRANPGMFSRITIDYYGAATPITQLASINVPEARLVVIKPYEANQLRAIETAIRNSDLGVNPTNDGALIRVAVPQLTEERRRELVKQAKHKGEEAKVSVRNIRRKAMEELHRIRKEGEAGEDEVGRAEKDLDKTTHQYVTQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSBP2_MOUSE
Sequence: MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV
What are the official names of this protein?
Single-stranded DNA-binding protein 2, Sequence-specific single-stranded-DNA-binding protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_RHIEC
Sequence: MAEAATRSVGKVTQVIGAVVDVAFEGELPAILNALETDNNGNRLVLEVAQHLGENEVRTIAMDSSEGLVRGQQVIDTGAPISVPVGDETLGRIMNVIGEPVDEAGPLNTAHKRAIHQDAPAYVEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVNKHGGGEGSKAALVYGQMNEPPGARARVALTGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITTTTTGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPMVVGEEHYEVARKVQSTLQRYKALQDIIAILGMDELSEEDKLAVARARKIERFLSQPFFVAEVFTGSPGKLVALEDTIKGFKGLVNGEYDNLPEAAFYMVGSMDEAIEKAKKLAAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVD_METHJ
Sequence: MRSDDVKAGYARAPNRSLIRSLGIDESEMHQPFIGIANSWNTIVPGHTHLRVLGERVREGITAGGGTPFEFNTIGICDGIAMGHEGMRYSLPSRENIADSVELMIQAHKFDGIVCICTCDKIVPGMLMAAGRCNIPAIVLTGGNMLPGNLHGCELSLTDVFEGVGKVAGGTMTEEELTELETAAMPGCGSCQGLYTANTMACMTEALGMSLPGCAATPAVYADKIRLAYRTGKRIVDLVRKQILPRDIITPASLRNAIRVDMALGGSTNTVLHLMAIATEAGVPFDLQEFNRLSEQIPHIASMMPAGPHSMQALHHAGGIPAVFRQIRSHLENCQTVSGMDIYTIADSVKYVDESVIRPEQSPVHQSGGLMILTGSLAPDGAVIKSGAVQDEMWKHTGPARVFDGEELAMKAILAREIKEGDIIVIRYEGPKGGPGMPEMLSPTSALVGLGYSRVALITDGRFSGGTRGPCIGHVAPEAAAGGPIAFVKDGDQISIDLFTKTVNLNISADEIENRKKGWKPLKRPLTGVLARYAAAVGPADLGAVLQ
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SRY_BOSGF
Sequence: MFRVLNDDVYSPAVVQQQTTLAFRKDSSLCTDSHSANDQCERGEHVRESSQDHVKRPMNAFIVWSRERRRKVALENPKMKNSDISKQLGYEWKRLTDAEKRPFFEEAQRLLAIHRDKYPGYKYRPRRRAKRPQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNKVTLATRISADFPFNKSLEPGLSCAYFQY
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: RS15_ECOSE
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: G6PI_DEIGD
Sequence: MRDSSSPARPSLTQLPAWQALKSHFETMRDRHLRDLFAADPRRGERLVAEGAGVYLDYSKNRITDETLRLLLQLAREAGVEARRDAMFAGERINLTENRAVLHSALRAPRGAAVTVDGTNVVQEVQEVLDRMSAFADRVRAGTWLGATGKPIRNIVNIGIGGSDLGPVMAYEALKFYADRRLTLRFVSNVDGTDLVEKTRDLDPAETLFIVSSKTFTTLETMANAQSARAWLLAGLENVPDENAAIARPIISRHFVAVSTNAAEVERFGIDTANMFGFWDWVGGRYSVDSAIGLSLMIAIGPNGFRDFLAGFHAMDEHFRSAPLEQNLPVLLGVLGVWYRNFFGAQTYAVLPYDQYLAYFPTYLQQLDMESNGKHVTLDGQPVDYDTGPVVWGQPGTNGQHAFYQLIHQGTTLIPCDFLGFCQTLNPLPTPGGPSHHDLLMANMFAQTEALAFGKSLEQVQAEGVAADLAPHRVFEGNRPTNTLLLDRLTPRTLGTLIALYEHKVFVQGAIWNINSFDQWGVELGKVLASKIVPELEAPGEPELKHDSSTNALIRRYRARRR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_HELP2
Sequence: MQFHSSSALITPFKKDLSVDEAAYEALIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCKNTKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKTIAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREIPNIKAIKEASGSLKRVTELHYHEKDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKLEYQQALEIQNKLFHLHQALFVETNPIPIKMAMHLAGLIENPSYRLPLVAPSKETIQLLEKTLQQYEVIA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_XANC5
Sequence: MTQKTILNDTHRALGAKMVDFGGWDMPIHYGSQLDEHHQVRRDAGMFDVSHMTVVDLHGARVREFLRYLLANSVDKLKVSGKALYTCMLNPQGGVIDDLIVYYMTEDFFRLVVNAATREKDLQWIGEQAARFDVRVEERSDFAMIAVQGPGARTKVIDLLDPADTAAASKLGRFAALQTRSRDGIDLFLARTGYTGEDGFEIVLPQEAAVAFWNALLAQGVKPAGLGARDTLRLEAGMNLYGQDMDDGVTPYEAGLAWTIALDEGRDFIGRSVLEYQKAQGAPRQLIGVVMDEKGVLRHGQTVLTASGEGEILSGTFSPTLGKAIAFARVPAGSIEQLRVDIRGKQVPLRAVKFPFVRDGQAQPGVLGD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.