PharMolix/UniProtQA huggingface dataset:
Protein: PURE_MYCTU
Sequence: MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQRLAGKLTRD
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: RNC_YERPA
Sequence: MNPIVINRLQRKLGYTFQQQELLLQALTHRSASSKHNERLEFLGDSILSFVIANELYRRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIHTIERLILEWYHSRLEEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLNEPVIGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBZ_TOBAC
Sequence: MTLAFQLAVFALIATSLILLISVPVVFASPDGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=Associated with the photosystem II complex.
Protein: RS2_STRA1
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVAEEAKRAGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEEGTFELLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITSKLADAVIEGRQGEDADVDFAQEAQADSIEEIVEVVEGSKND
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NANA_SALHS
Sequence: MAKALQGVMAALLTPFDHQQQLDSESLRRLVRFNIGQGIDGLYVGGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVSALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVLSVPLCRKPFAPVDEKYLPALKALAQQLMEEKA
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCP2_ASHGO
Sequence: MSLPLRNPLDSVSLERALEDLIVRFIINVPPEDLATVERELFHFEEAQWFYTDFVKLTNPHLPNMKFKTFASYVISLCPLVWKWQDVNPEEALQKFSKYKKSIPVRGAAIFNETLNKILLVKGTESDSWSFPRGKISKDEDDVDCCIREVMEEIGFDLTNYVLEDQYIERNIGGKNYKIYLVKGVPQDFAFKPQVRNEIEKIEWRDFWKLSRSIHKSNNKFYLVSSMVKPLSLWVKKQKQIQGEEQLKQYAEEQLKLLLGIGTQEEAADPGRDLLNMLQSSVGQKKPLVFSDDESQASISTSAPTTVPPAPSTANSQSVQPIAAGAYAGYPFPFPQYPIPGMQTINPFQFVQSSHQGVFATHSTFTTSHQYPQAQAPQTQQPVPGAVVYPVQSQLQQAYQPPHTPVVKPSVIEDRAPHSKQLLELLKNPRKPEVEDESTAKTLLKLLKNPTKENRTSANTVPSSKGAVSGPSGGRSISGQSIDTANLPSGMASSMGAKSTAIPLYSPRSSLSEMTLPDEPLGGYEEFESSSEEEQGEELAYMNLQEPTSSVMESNAKVENNTLDNISHVDTSGNLSTRSLQSEKTEKSKPTAKPKIKLLKRGETLTPLTPSISSQTATSESSAAGPTVPSEKDVSSRIQNSQGNELLDVLKSKAQPEPSVASTSPAKELLNTLNKPQGSVYQNLLFGANHRKSDDESSPRHSPVSQQARTHEFLNLLKRPQAKAENEELQSVLLTPPANSGMVQNSSTLPNIPYGNLHQDQAAALLFPQQPPQFQQPYAATNTNSKELLAILRKPASNQQKQLHEQTPANPVDQPTTLASEQQNLVKQQISNPSQSLQQGTPLQQPQPQHTQSPSNLHVTGNTAAAQELLGMLRKSRVVP
What is the function of this protein?
Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.  Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.  Decapping is the major pathway of mRNA degradation in yeast.  It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body (By similarity).
What are the official names of this protein?
mRNA-decapping enzyme subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DCP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: ICP27_HHV11
Sequence: MATDIDMLIDLGLDLSDSDLDEDPPEPAESRRDDLESDSSGECSSSDEDMEDPHGEDGPEPILDAARPAVRPSRPEDPGVPSTQTPRPTERQGPNDPQPAPHSVWSRLGARRPSCSPEQHGGKVARLQPPPTKAQPARGGRRGRRRGRGRGGPGAADGLSDPRRRAPRTNRNPGGPRPGAGWTDGPGAPHGEAWRGSEQPDPPGGQRTRGVRQAPPPLMTLAIAPPPADPRAPAPERKAPAADTIDATTRLVLRSISERAAVDRISESFGRSAQVMHDPFGGQPFPAANSPWAPVLAGQGGPFDAETRRVSWETLVAHGPSLYRTFAGNPRAASTAKAMRDCVLRQENFIEALASADETLAWCKMCIHHNLPLRPQDPIIGTTAAVLDNLATRLRPFLQCYLKARGLCGLDELCSRRRLADIKDIASFVFVILARLANRVERGVAEIDYATLGVGVGEKMHFYLPGACMAGLIEILDTHRQECSSRVCELTASHIVAPPYVHGKYFYCNSLF
What is the function of this protein?
Multifunctional regulator of the expression of viral genes that contributes to the shutoff of host protein synthesis and mediates nuclear export of viral intronless mRNAs.  Early in infection, this immediate early (EI) protein mediates the inhibition of cellular splicing.  This results in the accumulation of unprocessed 3'end pre-mRNAs which can't be exported from the nucleus.  Cellular protein synthesis is thereby shut off early after virus infection.  Later in the infection, it helps recruit cellular RNA polymerase II to viral replication sites and promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP.  ICP27 binds to NUP62 which may provide facilitated viral mRNA export and may indirectly compete with some host cell transport receptors for binding and inhibit cellular nucleocytoplasmic transport pathways (PubMed:22334672).  Also stimulates translation of viral transcripts.  Repression of host gene expression blocks the cell cycle at the G1 phase and prevents apoptosis.  Seems to silence the 3' splice site of the promyelocytic leukemia (PML) intron 7a, thereby switching PML isoforms from PML-II to PML-V.  This could be linked to the accelerated mRNA export induced by ICP27 which might not provide sufficient time for PML pre-mRNA to be spliced in the nucleus.
What are the official names of this protein?
mRNA export factor, Immediate-early protein IE63, Infected cell protein 27, ICP27, VMW63.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: CSPS_STRTR
Sequence: KNGTVKWFNAEKGFGFITSED
What are the official names of this protein?
Cold shock protein CspSt.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SHEB5
Sequence: MSEKKINLLDLDRKAMRALFADMGEKPFRADQLMKWLYHFGVSDFEEMTNINKVLRQKLAARCEIVAPEISSFQKSTDGTIKFAINVGQGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTGQQGFNRNLTVSEIVGQIWRVSHFLGFAKDTGERPITNVVMMGMGEPLLNLANVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDKLGDAIDVALAVSIHAPNDELRDILVPINKKYQLDEFLAGIRRYIAKSNANRGRVTVEYVMLDHINDSTDQAHELAKLMKDTPCKINLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGFTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQENQISVTMN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y270_BACFR
Sequence: MLLATTPIIEGKRITTYYGIVSGETIIGANVFRDFFASIRDIVGGRSGSYEEVLREAKDTALKEMSEQARQMGANAVIGVDLDYETVGGSGSMLMVTASGTAVFLE
What are the official names of this protein?
UPF0145 protein BF0270.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: NEU2_BALPH
Sequence: CYFQNCPRGXXXAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFMGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFPRRA
What is the function of this protein?
Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.  Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (By similarity).
What are the official names of this protein?
Vasopressin-neurophysin 2.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_PYRAE
Sequence: MQISDAWIRKVFTGRGDVTVEVELTVEDSVTGDVLVTRAAAPAGASRGAHEVLYFPEGGVDAALAAFEKLVAPEIVGLDVTEPYSTDGKLEEVDGTQRFEKIGGAVAIATSFAAAEAGAASLGVPLYSFIGGAYARRLPLPLGNVIGGGKHSRGLGPDIQEFLAMPLNPPDIYTAVYTNVEIHKRVLKYILKVDTSFTGGKNDEGAWTPRISSTTALKILREAAREVSGELGVEVGIGVDVAASSLWNGEKYVYKNEGVERDPREQFEFIAKLIEEYDLVYVEDPFHEEDFQSFAELRDRFKDRLIVGDDLFVTNPERIKKGGKIGAATGVIIKPDQIGTLLRAHQAVSAAREFGMRVIVSHRSGDTEYKTLAHIAVGFGAEVIKTGIMGGERTAKLNELIRIGDYLGKWATITQIRIH
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: BSPH1_HUMAN
Sequence: MGSLMLLFVETTRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDRIWKYCE
What is the function of this protein?
Binds sperm in vitro and promotes sperm capacitation.  Specifically promotes capacitation induced by high density lipoproteins (HDLs).  Also binds heparin, phospholipid liposomes, and weakly to gelatin.  Does not bind chondroitin sulfate B.
What are the official names of this protein?
Binder of sperm protein homolog 1, Bovine seminal plasma protein homolog 1, Bovine seminal plasma protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPE_HUMAN
Sequence: MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
What is the function of this protein?
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
What are the official names of this protein?
Glutamyl aminopeptidase, EAP, Aminopeptidase A, AP-A, Differentiation antigen gp160.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: EIF3D_PONAB
Sequence: MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDESSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMLQFNLQILPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLPTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEEEEEEEEEEEEET
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.  In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7, eIF-3-zeta.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_VIBA3
Sequence: MSHSNHFDVIVIGSGPGGEGAAMGLTKAGLNVAIIEKESSVGGGCTHWGTIPSKALRHAVSRIIEFNSNPLFCQNNKSIHSTFSNILGHAKSVIDKQTRLRQGFYDRNQCTLVFGTARFIDTHTISVMQSDGTEEHYSADKFVIATGSRPYQPDNVDFMHERVYDSDSILSLKHDPQHIIIYGAGVIGCEYASIFRGLGVKTDLINTRDRLLSFLDNETSDALSYHFWNSGVVIRNDETFEKIEGTDDGVIIHLESGKKMRADCLLYANGRTGNTDKLNLGAVGLEADSRGQVSVNSNYQTSVEHVYAVGDVIGYPSLASAAYDQGRFVAQAVVKGEAERHLIEDIPTGIYTIPEISSVGKTEQELTAAKVPYEVGRSSFKHLARAQIAGKDIGSLKILFHRETKEILGIHVFGERAAEIIHIGQAIMEQKGEANTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_GEOSL
Sequence: MERKNVESLFAHAGAINALVIGDLMLDQYLWGKAERISPEAPVQVVDVTREEIRIGGAGNVANNLVALGCRVSVASVVGGDENGTILLHAFSGKGIDVTGIVEDPSRTTSRKTRVLASNQQIVRIDRESRDEIGPDNERRIVDYLNAHGDRFNVILVSDYLKGVLTPTLLAEVIAFARKREIPVVVDPKGSDYAKYRGATVLTPNRKEAEAASGIAIRDDESLCRAGERLLETADLTALVITRSEEGMSLFLRGGQVVHIPTYAREVFDVTGAGDTVLAVLGMALAGGVGFADGARLANVAAGVAVGKVGTSTVSPAEIVGSLGFQHGEGDAKVKNLDVLAGIIAAEKAQGKRVVFTNGCFDLLHVGHVKYLQKARSFGDLLVLGLNSDASIRRLKGEKRPLIGQEERAHILAALDCIDYVVVFDEDTPLNLIETLRPAVLVKGGDYTLDGVVGREVVESYGGRVELVAFVDGRSTTNIIEKILKAYGEE
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: SYFA_CUPMC
Sequence: MSLDLDQVVADAQAAFAAANDNATLENEKARFLGKTGALTELLKGLGKLDPDARKTEGARINQVKQQVEAALQARRQALADALMNARLAAEAIDVTLPGRSVARGSVHPVMRTWERVEQIFGSIGFDVADGPEIETDWMNFTALNNPDNHPARSMQDTFYVDGRDSDDKLLLLRTHTSPMQVRYARMHVEKYAGRAMPPIKVICPGRTYRVDSDATHSPMFNQVEGLWIGDNVSFADLKGVYTDFLRKFFERDDIQVRFRPSYFPFTEPSAEIDMAFGNGKWLEISGSGQVHPNVLRNMGLDPERYIGFAFGSGLERLTMLRYGINDLRLFFEGDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_NOVAD
Sequence: MTSTNEIRRSFLEYFGSNGHDVVPSAPLVPYNDPTLMFTNAGMVPFKNVFTGLETRAVPRATSSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAITHAWTLLTREWGLPKDKLLATVYHTDDEAFELWKKIAGLPEDRIIRIATKDNFWAMGDDGPCGPCSEIFFDHGDHIWGGPPGSPDEDGDRFIEIWNLVFMQFEQTAGEITGSLPKPSIDTGMGLERIAAVLQGEHDNYDTDTFKALIAASESLTSVRAEGDHKASHRVIADHLRSTSFLLADGVLPSNEGRGYVLRRIMRRAMRHAHLLGAKDPLMHRLVPALVAEMGAAYPELGRAQPLIEETLLREEVQFRRTLSNGIKLLDEATATLGEGDKLPGDTAFKLYDTYGFPYDLTEDALRARGIAVDREGFDAAMAQQKAAARAAWKGSGQAADSEVWFDIAERVGATEFTGYTATTGEAQVVALVKDGKEVDSAMAGDDVAVIVNQTPFYGESGGQTGDAGTITGGDGLVLAVSDTAKPLGRLHAHNAKVQSGSVKVGDVVRLDIDVARRDAIRANHSATHLLHAALRHRLGAHVTQKGSLVAADRLRFDFSHPTALSAEDIAAIEAEVNAEIRANEVVTTRLMSPEDAIEAGAMALFGEKYGDEVRVLSMGRVADKHYSVELCGGTHVRALGDIGVFRIVSESAVSSGVRRIEALTGEGARQWFVAREDALKNTASILRTTPEDVEARVTALMDERKKLERELAEAKKALALGGGSAKAENADEDVNGVKFSGQVLEGLDPKDLRGLLDQAKQRLGSGVAVIVAVNEGKASIAAAVTDDLAGKVSAVDLVRAGVEALGGKGGGGRPDMAQGGGPEGSRAADAIAAARAVLTA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y056_CLOPS
Sequence: MARGGFPGGMGNMNNLMKQAQMLQKQMQSMQEEIEASEFEGSAGGGAVVAKVNGKKELIALNIKPEVVDPDDVEMLEDLVFSAVKQALEKASEETSEKMGKLTGGMGMPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CPR_0056.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ALKB8_MOUSE
Sequence: MNINHKGVLKLTKMEKKFLRKQSKARHVLLKHEGIQAVSYPTQSLVIANGGLGNGVSRKQLLLTLEKCGPVEALLMPPNKPYAFVIFQTIEESKKAYFTLNGKEIIDDLGQKIFLYLNFVEKAQWKNMGLEALPPGLLVVEEIISSEEEKKLLESVNWTEDTGNQNFQRSLKHRRVKHFGYEFHYESNTVDKDKPLPGGLPEVCSSILEKLLKEGYIKHKPDQLTINQYEPGHGIPAHIDTHSAFEDEIISLSLGSAIVMDFKHPEGVTVQVMLPRRSLLVMTGESRYLWTHGITPRKFDTVQASEQFKGGIITSDIGDLTLSKRGMRTSFTFRKVRRMPCNCSYSSVCDRQRKATPPSLTESSKEALELEQKHVHQVYNEIASHFSSTRHSPWPRIVEFLKALPSGSIVADIGCGNGKYLGINKDLYMIGCDRSQNLVDICRERQFQALVCDALAVPVRSGSCDACISIAVIHHFATAERRVEALQELARLLRPGGQALIYVWAMEQEYKNQKSKYLRGKRISQGDKDELNSATSTEEFLVNQTPEGVNEDPALSVNSSSITKEEEYKSRKVPNSELPIHINRTCFHSQDVLVPWHLKRNPGKDKAIEPSGVAGCPDPSPVFHRYYHVFCDGELEASCQAVGDVSILQSYYDQGNWCVVLQKV
What is the function of this protein?
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966).  Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966).  Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys) (By similarity).  Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:20583019).  Required for normal survival after DNA damage (By similarity).  May inhibit apoptosis and promote cell survival and angiogenesis (By similarity).
What are the official names of this protein?
Alkylated DNA repair protein alkB homolog 8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: RL20_CLOB6
Sequence: MARVKRAMNARKRHKKVLKLAKGYYGGKSKLFKTANESVIRALRNAYVGRKLKKRDYRKLWIARINAATRMNGLSYSKFMNGIKNAGIDINRKMLSEIAINDPKAFAELVDVAKKQLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: C89A9_ARATH
Sequence: MEITTIIFLIISSLTFSIFLKLIFFFSTHKLPPGPPRFPVIGNIIWLKKNNFSDFQGVLRDLASRHGPIITLHVGSKPSIWVTDRSLAHQALVQNGAVFSDRSLALPTTKVITSNQHDIHSSVYGSLWRTLRRNLTSEILQPSRVKAHAPSRKWSLEILVDLFETEQREKGHISDALDHLRHAMFYLLALMCFGEKLRKEEIREIEEAQYQMLISYTKFSVLNIFPSVTKFLLRRKWKEFLELRKSQESVILRYVNARSKETTGDVLCYVDTLLNLEIPTEEKEGGKKRKLSDSEIVSLCSEFLNAATDPTATSMQWIMAIMVKYPEIQRKVYEEMKTVFAGEEEEREEIREEDLGKLSYLKAVILECLRRHPPGHYLSYHKVTHDTVLGGFLIPRQGTINFMVGEMGRDPKIWEDPLTFKPERFLENGEACDFDMTGTREIKMMPFGAGRRMCPGYALSLLHLEYYVANLVWKFEWKCVEGEEVDLSEKQQFITMVMKNPFKANIYPRRK
What is the function of this protein?
Involved in the chlorophyll breakdown by its action in nonpolar primary fluorescent chlorophyll catabolite (pFCC) decarbonylation (Ref. 6, PubMed:23723324).  Involved in the formation of major chlorophyll breakdown products, including non-fluorescent dioxobilin-type chlorophyll catabolites (NDCCs), during leaf senescence (PubMed:23723324).
What are the official names of this protein?
Cytochrome P450 89A9.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.