PharMolix/UniProtQA huggingface dataset:
Protein: PDXS_THEKO
Sequence: MGKLDVIQAKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVSVMALHRVPADIRKAGGVARMAPIEKIQEIMDAVTIPVMAKVRIGHVAEAKILEALGVDMIDESEVLTPSDPFFHIDKREFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAVRHVRLVAEGIRQIQAMTDDQVYAVAEKFAEPYLRLSLNVKEIAGLPQRVLDNEPIYGHYTYREIVDGLYKILLEIKKLGRLPVVNFAAGGVATPADAALMMQMGMDGVFVGSGIFKSSNPPKMAKAIVEAVNHWDEPDVLVEISKEIGEPMRGQDIEELEVRLEERGV
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y1617_DEHM1
Sequence: MILTNTEDVAGHKIIKNLGLVKGNTIRAKHIGKDILAGLRSIVGGEIEEYTQMLDEARNEAIRRMEAEAKEKGANAIICVRFSTSAVMQNASEVMAYGTAVIVE
What are the official names of this protein?
UPF0145 protein DET1617.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PPNP_KLEP3
Sequence: MLQSNEYFDGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAQPEEMTVVSGALNVLLPGETEWKVYAAGEVFNVPGNSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: CCD1_PHAVU
Sequence: MGDDGKKNGAEGGLVKVDPKPTNGFSSKVIDLLEKLLVKFLYDSSLPHHYLTGNFGPVTETPPTKDLPVKGHLPDCLNGEFVRVGPNPKFAPVAGYHWFDGDGMIHGLRIKDGKATYVSRFVETSRLKQEEYFGRSKFMKIGDLKGLFGLLMVNIHMLRTKLKVLDLSYGGGTTNTALVYHHGKLLALSEADKPYAIKVFEDGDLQTLGMLDYDKRLGHSFTAHPKVDPFTGEMFSFGYAHTPPYITYRVISKDGYMHDPVPITISDPIMMHDFAITENYAVFMDLPLIFRPKEMVKNKTLIFSFDSTKKARFGVLPRYAKDEQHIRWFELPNCFIFHNANAWEEEDEVVLITCRLQNPKLDNVGGTVQEKLENFSNELYEMRFNMKTGEASQKKLSASTVDFPRVNENYTGRKQRYVYGTTLDSIAKVTGIIKFDLHAEPDHGKEKLEVGGNVQGLYDLGPGKFGSEAVYIPRVPGIESEEDDGYLVLFVHDENAGKSFVHVIDAKTMSADPVAVVELPNRVPYGFHAFFVTEEQLQEQAKL
What is the function of this protein?
Cleaves a variety of carotenoids at the 9-10 and 9'-10' double bonds.  Probably not involved in abscisic acid biosynthesis.
What are the official names of this protein?
Carotenoid 9,10(9',10')-cleavage dioxygenase 1, Neoxanthin cleavage enzyme NC2, PvCCD1, PvNCED2.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: PFDA_SACS2
Sequence: MSQGQGGITLDELIAQADYLKRYIDSLQRTQLELLESINSIDSAKQAIETMKSGNKEMLVFIDRKGYLLAKVGGIIGDKVTVHLGLSYYAEVDLDSAIKILDKRKDEISKAAQDLNNELQKAASTYNQIVDILNQIQQAAARRQQGE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_CELJU
Sequence: MSKGHSLQDPYLNVLRKERVPVSIYLVNGIKLQGQVESFDQFVVLLKNTVSQMVYKHAISTVVPSRAVRVPLLNEAGGAEGEEDEQAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL7_CERS4
Sequence: MADLNKLAEDIVGLTLLEAQELKTILKDKYGIEPAAGGAVMMAGPAAGAAAPAEEEKTEFDVVLTDAGANKINVIKEVRAITGLGLKEAKDLVEAGGKVKEAVAKADAEAMKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ANS1_YEAST
Sequence: MKCTLVSTLFAITNILVAHAQVSNSSDTLDVQFANSTNSYIEGKFNSTDEAFNSSASWSLAAQQKKISNAAVYDVGGWNGSLYRSNRSAVADHQPGKKQDAAISQISDGQIQATASGPETTAATTPSSTANVSVYEGAGMKVESKNMGYIVGVAALLFL
What are the official names of this protein?
Probable GPI-anchored protein ANS1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LCL2_CANTT
Sequence: MQYLLVALSLFISLSSANLFDFLNNFNHGGGGRQQQQGARNPQEYENRILNSQCDQYLCPDTGLCVESPKFCPCPYPSSQIRCFLPDGRFVCISKPAGEGISDKYNDPKTNWKIDAKDDNIRDCGWVNRAWRGLV
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: GUAA_CALS8
Sequence: MQHEIVIVLDFGGQYNQLIARRVRECGVYCEIWPYDTPLEKIIEKNPKGIIFTGGPSSVYEENAPVVDKKIFEIGVPILGICYGNQLIAYFLGGKVSTALFREYGKTHIKYNTNSPLFTGLPESSICWMSHTDFVEELPEGFEILASTENCAIAAFGSREKKIYGVQFHPEVVHTEFGQEIIKNFLFNICGCKGDWKTSSFIEERINEIRKIVGNQKVVCALSGGVDSSVAAVLVHKAIGKNLFCIFVDHGLLRKGEAEEVIKTFKGQFDMNVIKVDAKERFLKALCGVIDPERKRKIIGEEFIRVFEEEASKLGDVKFLVQGTIYPDVVESGVGKAATIKSHHNVGGLPEHIKFERIIEPLRELFKDEVRRVGVELGIPEKIVKRQPFPGPGLAIRIIGEVTEEKLEILREVDWIFRKEIEACGLDEEIWQYFAVLTDMRSVGVMGDERTYDYTVALRAVTSVDGMTADWARIPYDVLERVSNEIVNTVRKVNRVVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL20_CORJK
Sequence: MARVKRSVNAKKKRREVLKSAKGYRGQRSRLYRKAKEQMLHSKTYEFRDRKARKNEFRKLWIQRINAGARQNGMTYNRLIQGLRLAEIEVDRKNLAELAVNDFDAFTALCEAAKAALPEDVNAPAAS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ASSY_GEOSM
Sequence: MAKKEVKKIVLAYSGGLDTSIILKWLKNEYGCEVVTFSADLGQGDELEPVREKAFKTGADKVYIDDLREEFVRDFVFPMFRANAIYEGSYLLGTSIARPLIAKRQMEIAQIEGCDAVSHGATGKGNDQVRFELAYYHFNPGITVVAPWREWKLNSRQALINYAKRNDIPIPITKKRPWSSDRNLLHISFEGGILEDTWLEPPENMFVLTKPPEKAPNKPQYVEIEFEKGNAVAVDGVRMSPAELLAHLNTIGGEHGIGRVDLLENRSVGMKSRGVYETPGGTILREAHMAVEQITMDREVMHLRDSLIPRYAEMIYNGYWFSPEREMMQCMIDESQKTVNGVARLKLYKGHCRTVGRKSESDSLFNLDFATFEKDQVYNQADAEGFIKLNSLRLRIRSLMLANKNK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_ECOLU
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGEHVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWIAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_PSYWF
Sequence: MAILPILSYPDPRLRTIAEPIKTVDAEIKQLIKDMIETMYDAKGIGLAATQVDRHIQLIVMDLSENNDSPRVFINPKVTPLVEDKKPYEEGCLSVPDVYDSVDRPVKVKIEALDADGNAFEEIAEGLLAVCIQHEMDHLNGVLFVDYLSRLKQTRARDKVKKYLKTREKQLQHNKA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NDHL_NOSS1
Sequence: MIVPLLYLALAGAYLLVVPVALLFYLKLRWYVVSSIERTFMYFLVFLFFPGLLVLSPFVNLRPRPRKIEV
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PDRP2_STAES
Sequence: MKDNNEVLKLFIVSDSIGETAQRMIHATLTQFPDLTQVEIKKFPYIKDEQEFLNVLQLAKEQNAIVATTLVSESFNALGHQFANEHQIPYVDYMSELISIIKQHTHAKPLMESGALRKLNDEYFKRIEAIEYSVKYDDGKHFTDIGEADALIVGVSRTSKTPLSMYLANKGYKIANIPLVPEVAIPDNVFQQKNLKVFGLTASPNYIANIRRNRAETLGLSSESNYNSLERIKKELSYAEEVFRKLNATVINTEYKSIEESAFYIEKFLAKR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: MTNA_BACLD
Sequence: MPEQFAVPRSVEWEETSVKILNQQKLPEKTEYLHLTTKEDIYDAIQTLKVRGAPAIGITAAFGLALCAQSIDTSDVSAFLRELRKIKDELNQARPTAVNLSWALNRLLKSAEGAKSVNEAKTNLVHEAIQIQVEDEETCRQIGQNALHLFKSGDSIMTICNAGSIATSRYGTALSPFYLAKTKDLDLHIYACETRPVLQGARLTAWELMQGGIDVTLITDSMAAHTMKEKNISAVIVGADRIARNGDTANKIGTFGLAILAKAFQIPFFIAAPLSTFDVSISCGDDIPIEERDPDEVRRINGTQIAPQEVPVFNPAFDITPHDLISGIITEKGIITDRFEEEIEALFSAEALT
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: EFTS_LISMH
Sequence: MANITAQMVKELREKTGAGMMDCKKALVETEGDMEKAIDYLREKGIAKAAKKSDRVASEGMTHVISNEKHAVVLEVNAETDFVAKNDNFQQLVDALAKQILAVRPDSLEDALKTEMPNGQTVQDYITEAITKIGENISLRRFEVKEKADNSAFGEYIHMNGRIGVLTLLEGTTDTTVAKDVAMHIAAINPKYISREDVSTEEVEHEKEVLTQQALNEGKPANIVEKMVEGRLKKYLSEISLEDQPFVKNPDITVGDYVKQSGGKVVSFVRFEVGEGIEKKEDNFVEEVMSQVKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_CERS1
Sequence: MATATLTIDLDAIAANWRALDQMTASDCQTGAVVKADSYGLGAAKVAHALARAGARRFFVATCEEGADVRRALGSGPQICVFSGHMEGDTALIRDFDLTPMLNSIDQLTRHFEALGGQPFGLQLDSGMNRLGLEPGEWEAVAGFALEAGPELLMSHLACSDDPDHPMNAEQLGAFRAMTDGTGVPRSLSATGGILLGPAWHFELTRPGIGLYGGRPFEEARPVVRLSLPVIQVREVEIGEPVGYSNTWTAEHTSTIATVAAGYADGLPRTLSSRATLYAGRVPCPLVGRVSMDLITVDVSHLPEVPETLDILGPHQTPDDLADTAGTIGYEILTSLGRRYQRRYGALAA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: UREG_KLEP3
Sequence: MNSYKHPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGALAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLGK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPH_CHICK
Sequence: MAGRLSESVGSGPGAEAETAADPDAKRDVLEHLCARTHLKQLVMEFDTACPPDEGCNSGAEVNFIESAKETLEEVGKVKSAFESKALVIKRIQLMDALRKRVKENDGCARLIVETMRDIIKLNWEIIQAHQQARVIRENLNDIRRKRYFLKQAEGEKALRIFTTVRKKKEVVRMKIAEKLKFIHRNVQYERKVTTLVQNILQNIIVGCQINWAKDPSLRAIILQLEKDISIQNLL
What is the function of this protein?
Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  Required for the localization of CENPC but not CENPA to the centromere.  It however may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
What are the official names of this protein?
Centromere protein H, CENP-H.
What is the protein family that this protein belongs to?
Belongs to the CENP-H/MCM16 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associates with active centromere-kinetochore complexes throughout the cell cycle.
Protein: SYY_STAAB
Sequence: MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYGLTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAKELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNYALAPEDKIDGEFTIIRRGKKKYFMVNYQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_PARDE
Sequence: MAAKEVKFNSDARDRMLKGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELSDKFENMGAQMVREVASRTNDEAGDGTTTATVLAQAIVREGLKAVAAGMNPMDLKRGIDVATAKVVEAIKSAARPVNDSSEVAQVGTISANGESFIGQQIAEAMQRVGNEGVITVEENKGMETEVEVVEGMQFDRGYLSPYFVTNADKMIAELEDAYILLHEKKLSSLQPMVPLLESVIQSQKPLLIVAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLQDIAILTGGQVISEDLGMKLENVTIDMLGRAKKVSINKDNTTIVDGAGEKAEIEARVSQIRQQIEETTSDYDREKLQERVAKLAGGVAVIRVGGMTEIEVKERKDRVDDALNATRAAVQEGIVVGGGVALVQGAKVLEGLSGANSDQDAGIAIIRRALEAPMRQIAENAGVDGAVVAGKVRESSDKAFGFNAQTEEYGDMFKFGVIDPAKVVRTALEDAASVAGLLITTEAMIAEKPEPKAPAGGMPDMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_METAR
Sequence: MGITARKVLGTPYANGAKLMFLGAGELGKETMIEAQRMGIEIVAVDRYANSPGMQVAHRSYVTNMKSERALLAIVEKEKPDAIIPEIEAINTDTLFKLEKEGFFVAPCANAVWTAMHRERLREAIASTGARTSKYEYATDLESFKAACKKIGFPCVSKPIMSSSGKGSYVLKSSKDVEKAFKEAAKARGSSDKIIVEEFIDFDVEITALSVRYLNGKGKPESKFVRPLGHYQIEGDYHASWHPWTDATDKKIDKLEKEIYDYAGRIMDKLGGYGLFAHEMFVDTKNGKVYANETACRPHDTGLVTIASMPFGYSEFALHAKAVLGIPIACEGKVIQPRSTAASHVILSHTEGWYPQFKVDGAYAPDTNVLIFGKPEAYEERRLGVVLATAGTVEDAKKKAQKAAHTVKVSANDKWAGQEITEKHYR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: LSM1_DICDI
Sequence: MSSGLGDEVDKKLIVVLRDGRKFIGIMRTFDQFANIVLQDTIERIYVGDCYSDKNLGLFFIRGDNVVILGEIDPDKEVQEKKLKKISWDEITKAAALEKIKKEEEEQLKRRIMTESGLTIDSILNIDDF
What is the function of this protein?
Probably involved with other LSm subunits in the general process of degradation of mRNAs.
What are the official names of this protein?
Probable U6 snRNA-associated Sm-like protein LSm1.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: NQRA_HAEIE
Sequence: MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVIFTAPASGTITAINRGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQNLIESGLWTALRTRPFSKVPSIESEASSLFVNAMDTNPLAADPSVVLKEYSQDFTNGLTVLSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWHINYQDVIAVGKLFTTGELYSERVISLAGPQVKEPRLVRTIIGVNLSQLTQNELSAGKNRVISGSVLCGQIAKDSHDYLGRYALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKKLFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIVGDTDGAQELGCLELDEEDLALCSFVCPGKYEYGSILRQVLDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: CG025_XENLA
Sequence: MSVDSMLCDRIDIAKQLIKRSEALSRSRVGGVEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLRSTNLTHLQAVIESAESLEEVVSVLHVFSYNDQFGEKQSLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSVIEQAEDYLLASSQQLVQYSSPHIIFAFYNSVSKPMAEKLKEIGISVRGDIVAVNTSQENLPEENYLSGSESDCDGDDTAVLHVSKVDTENIVASIAFPTEIKVEACKRVNLDITTLITYVSALSHGGCHWLFKEKVLTEQAAQERQEKVLPLLKSFMEAKELFACESAIKDFQSILETLGGPAEKERAALLVKSITVVPDQPSERASKLACSSKINSRSISIFGTGETLKAITMTANSGFVRAAANQGVKFSVFIHQPRALTESKESSATPLPNNYASSNLL
What are the official names of this protein?
UPF0415 protein C7orf25 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0415 family.
Protein: CIDEA_MOUSE
Sequence: METARDYAGALIRPLTFMGLQTKKVLLTPLIHPARPFRVSNHDRSSRRGVMASSLQELISKTLDVLVITTGLVTLVLEEDGTVVDTEEFFQTLRDNTHFMILEKGQKWTPGSKYVPVCKQPKKSGIARVTFDLYRLNPKDFLGCLNVKATMYEMYSVSYDIRCTSFKAVLRNLLRFMSYAAQMTGQFLVYAGTYMLRVLGDTEEQPSPKPSTKGWFM
What is the function of this protein?
Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion (PubMed:18509062, PubMed:22144693, PubMed:26609809, PubMed:36477540).  Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage (PubMed:18509062, PubMed:22144693, PubMed:26609809).  Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets (PubMed:18509062, PubMed:22144693, PubMed:26609809).  The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC (PubMed:18509062, PubMed:22144693).  May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein (PubMed:22245780).  By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (PubMed:22245780).  When overexpressed, induces apoptosis; the physiological significance of its role in apoptosis is unclear (PubMed:9564035).
What are the official names of this protein?
Lipid transferase CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
What are the subcellular locations of this protein?
Lipid droplet. Nucleus. Note=Enriched at lipid droplet contact sites. Using a GFP-tagged construct, has been shown to localize to mitochondria, where it could interact with UCP1 and hence inhibit UCP1 uncoupling activity (PubMed:12910269). These data could not be confirmed (PubMed:22245780, PubMed:18509062).
Protein: RL13_SCHPO
Sequence: MAIHVKGQLPNAHFHKDWQRYVKTWFNQPGRKLRRRQARQTKAAKIAPRPVEAIRPAVKPPTIRYNMKVRAGRGFTLEELKAAGVSRRVASTIGIPVDHRRRNRSEESLQRNVERIKVYLAHLIVFPRKAGQPKKGDATDVSGAEQTDVAAVLPITQEAVEEAKPITEEAKNFNAFSTLSNERAYARYAGARAAFQKKRAEEAEAKKK
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: DNAK_MESFL
Sequence: MAKERIIGIDLGTTNSVVSIMEGGQPIILENPEGQRTTPSVVAFKNEDIIVGGAAKRQAVTNPNVVISVKSKMGTNEKIDINGKKYTPEQISAEILRYMKKYAEEKVGEKITKAVITVPAYFNDSQRKATKDAGKIAGLDVERIINEPTAAALAYGLEKKDKEEKVLVYDLGGGTFDVSILELADGTFEVLSTSGDNKLGGDNFDTQIINWLIEKIKTESGVDLKNDKMALQRLKDEAEKAKINLSSQLEVEINLPFIAMNENGPVSFSTQFSRTEFDKITKDLVERTSKPVKDALQAAKLSASDIDEVLLVGGSTRIPAVQKIVKELLGKEPNRSINPDEVVAMGAAIQGGVLAGDVTDVLLLDVTPLSLGIETMGGVMTKLIDRNTTIPTEKSQIFSTAVDNQPAVDINVLQGERPMAADNKSLGQFQLTGIKPAPKGTPQIEVTFKIDVNGIVSVIAKDKATNEEKSITISNSGALSDADIEKMIKEAEANAEADEIKRKNIELKHKAESYVAIIESSLTQEGQEIPQEQKEQAEKMVAEVKELIEKEDYEALETKVNELEQMIQMASQFAQAQTAQPEEGNSDSEENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.