Protein: TOM1_ASHGO
Sequence: MVVTLTKLERLQKAEKSRTFKPLIDELINCEDAVFVGKLEAIREWDRPKDDLFLWIPVLDRMDDMLGKVVAKYKYHTTDCKRHPVKLIEMAKPDEDWVATLLFFTCRLLNNTSNRSLYSSLDMMSDLLNCPNFRVKLGAMKVIATIGERHVVARHRIENSSVLASQHLKKRSLSLALALPSSTTDDNSDHFSLVDLFFDKRKYPSKWSQLQYTYYITKKQAGQQSTQKPSQVSSMKRFVLNNEELRFLSLQQIFDRAMNDLPSEFWFDFSLQASIAKAFSDDSFENIQLRSLIIQTKFAAIAFANAIYIPPQVSSKLFEMDPYAFNNLTDFISLSETKIPKDLRTDALFALECISLKHVWCSDIVRNLGGNMSHGLLFQILRYIAKVLREGDEDAVDEEYNVRFFYLISNLADVKALQESLISAGLISSLLEIVSTQNSKYKRTLASAAHLLEDVISDADATAEFINNNGFNILIQTVTYEVNFAVQNPSSAEPPKYSVVYYSISFRQLGFIRSLLKLVLKLLKTDSGDRIRNLIDSPILLAFNKILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQFLGPTSDLLCMLPEVISAICLNTDGLKQVKEKNLLKYLFQVIKTPEFAKILSWEDQAVNYGVALDELARHYPELKPLIEDYFAATVKELPSLTSYTHSYLYESTAGNGEFYLSENETIIDNEDGADELAFWEVQESSPIIDCFSGVFYSMASENISWANLTEKIAFQDFLSVAIPEKPTFDYINSQTLLNFTDVLKMFDDERRSYALPELLTILDSKFADLEDFLSYDFTKSYVLNEPKDRVVATLNKLNVLNVILYIMTDIYINITTLFPVRVIQMMEFFEKNGFNLITNLRKMFQRCVLEEMYIRSRLPPAVAEETISPGISFVPPILIHKDVPLKTEAKQEKTSAKFKNTLETRHLFQKVQSWTSMLFRCFLRLTHARKMNVERYDRALEIRIFDKVVNEIVEMLNLDYLDSHLSYFLVVLDFNTHIFTCPKASLTISDGIVQTVPTFLFYQAGGFAIYHELIKKLSTRLLGFDGIEAIEKVEYVKDQDDILTVGVLMNSIAFMNRCIQLETMENIRSIAEYYPYDDIYYNLTRALIVPVKILSLGAISEIFSQGEVFDTDRRRIPYSVFKQILSLLKNIYNSTFELEEGTDVYELRWDLMPISHRKVEMLKSCGISHDVAVGYLEEEKDELPIHVKPDVFSDSEWQRYQEERSSGSWRTNIELLPPQYNGSSTRETLSKMRTEFYQNGFESGILKILQHYPKLINAISHMFFEMYGELGFSHTTMLEDLQDMMNTIPIENTNKLAPVIHLFGIFLNDKNIYDQAKKEIFKFVSYLSMNLHPENVNYSWFSKALYVYEIIFAKSETPEASPLPENVTVSFSSIPIIYRISQKDKDIIFNLLIRANEVTDFYSALAISRILILYTREERYAQEVTQSGILSKLLKVIGANQKFDKINYLESSYLLLVRRCFETKEIVTSLIDYELTRAFTTRAIGDHKEKPRDLPALVNEKASIVMRDPEVFVNRISETARFEDFNSSKELASLSVRRHMDEKDEEMTSKPLSSEGSNSPITGIVHLLLSQLMAAHKRDWVSETPLTPEEENQKNKKKKDEVKVSKNPVCAYMIFLLKVLTELVSSYKQSKFEFLTYNKKNVYNETPKPRATALNFFLYQLLDTNFQDMDKHEGKRRAMISGLARDTIIGFVSSVQDSETKKVDPKIVDSDMTYIRKFTIEAISKAIKEAGVSAKTIDANAGKLFGWFHLISSLLVVDKGYIFSVLDSNKSSNDKYQLCKLLIEMNTPGTITDCMASLDLNYPLTKKLFNSAVEPLNALNEVRNNFADLFKLENNEDEDVEDVESDKDDVPDMFKNSALGMYDIEDVEDDHDDDENESLIGDDEDIAFVHDEDGLEVVFSEDEDANEDTTDASNSIGSDSEGNSDFGGSGPNVTLEVYTDSEDAIEDVNTAAIRITSGNSAEHSYYSEGEDSAEIEIYEEEYDSEIDIDMDDDSELGSSNWESGLSDLSDSEAYSDEERTNNTGDGFVRWYSDDGVEFEDDTDEEGRGLFTGIQHVFPTEEQLFRVHASGAARSTGRHHHRHGAAPFTTSTITLGASQRRPHSILSNPLGPSGLEEVENDIVSHYLGNVETSDRIGLSSIPRLPRVLLFDGELFDDKSSSGILLKSTTARWNDIYEMFYDSKVYSNNVVTTIISRIFEPSAELYLKEQEENAVKESSRINEPTRRQDERKRKLHEIDSDEEHIEEEEEHDEVVEPIEAPGINSPQARAPQEPVYVTIDGEAVNIAGTDMDAEFLNALPDDIRAEVFAQHIREYRTQFQGSEGSSRELDAGFLNTIPETLRQEILAQEVPLERNARPSILGLRNREGEEFSEVEDESPRFNEQRTESSKTKTDRVHFAPLLDRSGIAAIMKAVFIPQPYLSREIYHELFYRLCSSKQNRSDIMNMLLLILMDGINDQHSLERVYNLLSNRAASSNSGTSKTPQRQLPPDCTPLIVTNQCIEILQSMVDADSKLKYFFITEHENLLINKSPLKNKKDIFSKNMKWPINCILALLEKKVITDEAVLMDLLTRILQVCSKPISSIVKSSKDGKKKKFEVPDIEKKYLASIVSIIKLDSCNTKVFQQTLNLMTNLFAIKDAHETFTTELCNLAKETIEVLVTDLDALAKEVPAVDSGTEVSSEIIQKFTVPSSDQSKLLKVLTAIDYIYVNRKKEEEQVVDQLLPLYNKMELGHIWVSLSNCLTRFEEKPRMSTSATILLPLIESLMVVCKHSKVRETKDALLKYEAKKCDFARTPVENLFFAFTDLHKKLLNEMIRSNPKLMSGPFSLLVKNPKILDFDNKRYYFTAQLRAITHDRPKLSISVRREHVFLDSYRSLFFKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGIA
What is the function of this protein?
Probable ubiquitin ligase protein, which may be involved in mRNA export.  E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.  Participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase TOM1, HECT-type E3 ubiquitin transferase TOM1.
What is the protein family that this protein belongs to?
Belongs to the UPL family. TOM1/PTR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.