PharMolix/UniProtQA huggingface dataset:
Protein: TLE2_MOUSE
Sequence: MYPQGRHPTPLQSGQPFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSYPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQNQLQPLSHAPPVPLTPRPAGLVGAGATGLLALSGALAAQAQLVAAVKEDRVGVDAEGSRVDRAASRSSSPSPPESLVEEDHPSSRGGSGKQQRAEDKDLSGPYDSEEDKSDYNLVVDEDQPSEPPSPVTTPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSASHLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVGLHLSPQVSSSVVYGRSPLQMAFESHPHLRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVGQPGSKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
What is the function of this protein?
Transcriptional corepressor that binds to a number of transcription factors.  Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling.  The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
What are the official names of this protein?
Transducin-like enhancer protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARNT_SALG2
Sequence: MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQQYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNVDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRIM3_MOUSE
Sequence: MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPEGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGVRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
What is the function of this protein?
E3 ubiquitin ligase that plays essential roles in neuronal functions such as regulation of neuronal plasticity, learning, and memory (PubMed:24086586, PubMed:26527743).  In addition to its neuronal functions, participates in other biological processes such as innate immunity or cell cycle regulation (By similarity).  Component of the cytoskeleton-associated recycling or transport complex in neurons, polyubiquitinates gamma-actin, thus regulating neuronal plasticity, learning, and memory (PubMed:26527743).  Ubiquitinates postsynaptic scaffold GKAP, a neuronal substrate involved in synaptic remodeling and thereby modulates dendritic spine morphology (By similarity).  Positively regulates motility of microtubule-dependent motor protein KIF21B (PubMed:24086586).  Induces growth arrest via its RING-dependent E3 ligase activity and ubiquinates CDKN1A.  Positively regulates TLR3-mediated signaling by mediating 'Lys-63'-linked polyubiquitination of TLR3 (PubMed:26527743).  In turn, promotes the recognition and sorting of polyubiquitinated TLR3 by the ESCRT complexes (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 3, RING finger protein 22, RING finger protein HAC1.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network. Cell projection, dendrite.
Protein: YDHQ_ECO57
Sequence: MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKANDTLLADGTMNNLGGEDSDTIVENGAIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSIGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVNGDIRVQITDASRQTLCNALKLQPDEDGIGATLQPA
What are the official names of this protein?
Uncharacterized protein YdhQ.
Protein: MURD_CLOB8
Sequence: MKKDFNEFKEFIVGKKVGVVGIGVSNIPLINFLIDLGAAVTAFDKKNLEELGDVADGFNKKGVKLELGEKYLDNLKGFDVIFKTPSMRIDSEALVRARKEGAYVTSEMEEFVRYTRGKVYGITGSDGKTTTTTIISKLLEGQGYKTWVGGNIGTPLFSEIENIHDEDKVVLELSSFQLMTMTQEIDVAVCTNLSPNHLDMHKSMQEYIDAKKNIFIYQNSNGLLVVNRENEITHGFIKEAKGNVKEFSSKRELIDGAYYKNGILYLEDKEVCKKDDIVIKGMHNVENYLAAFLATKDDVSVEVMKKVAETFAGVEHRCELVREIDGVKYYNDSIASSPTRTLAGLRAFDEKVIVIAGGYDKNIPFEPLAYEGYPYIKELILMGATKHKIKDVFDNLENEKGIKININMVESLEEAVRLAESIANQGDIVTLSPACASFDMYPNFMIRGNKFKEIVKSL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKCB_BACSU
Sequence: MEKKKRELDIVLLLILLASAFLNIYNIWKDDTVNPYYTAAVTSMMQSFHNFFYASFDAAGFITVDKPPVTYQIQTISALIFGMHGWSVILPQALAGVGSVLLMYLLIKPTFGKTAARIASFVMACTPIAVAVARTNNVDALLVFFLLLATWLLFKAIRKGKLIWLLAAFFVVGVGFNTKMLQAYMILPAFLLFYLIAANATIKKKIVSLVSALAVLAAVSLSWPLIVDNIPASKRPYIGSSQTNSVLELAFGYNGIQRLTGQNSGGGQGAPNKDASKEMSSSDNTQAPPNQSSSNSSSSDGKSSNGNMAAPPSNGQMPSGGQGGPPSGGDGGQGGPGGDGGKGGTGTGSKMQSGSGMFGTGTPGPLRLFQQELSDQISWLLPFAIFGIAGLLIAGARERRRLSVEQKETVFWVAWLVPIAGFFSVAEFFHHYYLIMLAPPIAALVGAGWVALVHLYRNQTGWKAWLLPGAIIATTGFELFILRNYNDQIGVGWSIGVGVIGVLSAIALLLFKQRQKPFSYYVSLAALLALLVMPMYWASTPLLYGGNSSLPETGPQLASMSGKGMGMSDATVNEKLIKYLEENNSGAEYLFATTDSNTAAPYIIKTKKAVMAIGGYSGSDPAITLTQFKKLVKEGKVKYFLASGMGRGGNNDIVEWVEKNGKEVASEKWQSSSDQKTENTDSADTSSSKASGENGKMGGPGGMNQSATLYELHADE
What are the official names of this protein?
Putative mannosyltransferase YkcB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DF135_ARATH
Sequence: MSKTFQPSIVMLTIFLILVTSQRRKCDEKIVLQFCNGRNRCYEYCDTKECVAACKKKRNGEGICNGDVFSVSAQCLCLYKC
What are the official names of this protein?
Putative defensin-like protein 135.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: H2A3_VOLCA
Sequence: MAGRGKGKTAGKKAVSRSAKAGLQFPVGRIARYLKKGKYAERIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKNRIVPRHIQLAIRNDEELGKLLGDVTIASGGVLPNIHAVLLPKKSKGGKGEEAA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A-III.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TAUB_YERPE
Sequence: MLNVSGLWAEYQGKPALQDVSLQIASGQLVVVLGPSGCGKTTLLNLIAGFMTPSAGVITLDNIPVSGPSAERGVVFQNEGLLPWRDVVSNVEFGLQLAGMSKEQRRVTALKMLNRVGLAGFEHHFIWQLSGGMRQRVGIARALAVDPRLLLLDEPFGALDAFTREQMQELLLTIWRDTGKQILLITHDIEEAVFLASELLLLSPGPGQVVERLSLNFGQRYAEGEPCRAIKSDPEFIARREDVLGKVFQQREVLI
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS4_PSEU2
Sequence: MLIIPAIDLKDGACVRLRQGRMEDSTVFSDDPVAMAAKWVEGGCRRLHLVDLNGAFEGQPVNGDVVTAIARRYPNLPIQIGGGIRSLETIEHYVKAGVSYVIIGTKAVKEPEFVAEACRAFPGKVIVGLDAKDGFVATDGWAEVSSVQVIDLAKRFEADGVSAIVYTDIAKDGMMQGCNIPFTAALAAATRIPVIASGGIHNLGDIQALLNAKAPGIIGAITGRAIYEGTLDVAEAQALCDREQR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_MYCBO
Sequence: MMIARMETSATAAAATSAPRLRLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFLRDLASSTAQENVFNGLVAAFLWFTVLFANFAEAMAEGRGKAQAAALRKVRSETMANRRTAAGNIESVPSSRLDLDDVVEVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVVLSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALNILLAGLTIIFLLAVVTLQPFAIYSGGGQRVVVLVALLVCLIPTTIGALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNRQATEFVPINGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARDEGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGHPTEEVGAIVDGISSGGGTPLVVAEWTDNSSARAIGVVHLKDIVKVGIRERFDEMRRMSIRTVMITGDNPATAKAIAQEAGVDDFLAEATPEDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTGTQAAREAGNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMFVGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAESASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVALGVS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSD_AZOSB
Sequence: MSDRLAVLPQYLLPKQRLTLFMGRLAGARAGSLTTAVIRWFIARYGVDMSEAENPDPAAYASFNEFFTRPLRAGARPLAQADFICPVDGAISQFGAIERDQIFQAKGHRYTTTALLGGDRELATHFDHGHFATLYLSPRDYHRIHMPCAGRLTRMIHVPGELFSVNPTTARGVPGLFARNERVVCVFDGEHGPFVMVLVGATIVGSMATVWHGVVNSPRPGMIRDWRYPEGQVVLGQGEEMGRFLLGSTVVMLFPQDCLRFNAEWAPEKAIRLGEKMGDLFSCTPQAV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NDHI_STESO
Sequence: MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPMDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ATPA2_PSEA6
Sequence: MQLNSTEIAELIKQRIEQFEVVSEARNEGTIVGVTDGIIRIHGLADVMQGEMIELPGNRYAIALNLERDSVGAVVMGPYADLQEGAKVTSSGRILEVPVGRGLLGRVVNTLGAPIDGKGAIEADGFEPVEKIAPGVIERQSVDQPIQTGYKSVDAMIPVGRGQRELVIGDRQTGKTALAIDAIINQKDSGVKCVYVAVGQKASTIANVVRKLEEHGAMAHTIVVAASASESAALQYLAPYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNENYVENFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGIRPAVNAGISVSRVGGAAQTKIVKKLGGGIRLALAQYRELAAFSQFASDLDEATRAQLEHGERVMELMKQNQYAPLSVADMSVSLFAVEKGYLKDVELDKILDFEAALHSYMNSEYAELIKTINDTGNFNGEIEATLAEALEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL18_CHLL2
Sequence: MSQIDKASRRQKIKDRSRKQVHGNEKKPRLCVYRSLSQIYAQLIDDDNGKTIMSVSSMSKENRALEGTKCDVCRIVGLQLGEKAKAQGITKVIFDRNGFRYHGRVKALADGAREAGLVF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RBFA_BACC1
Sequence: MKLRANRVGEQMKKELGDIISRKIKDPRVGFVTVTDVQVSGDLQIATVYISVLGDEEQKESTLKGLAKAKGFIRSEIGQRIRLRKTPEISFEFDESIGYGHRIDTLLHEINKEGKREE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA1A_CONPE
Sequence: GCCSLPPCAANNPDYC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin blocks mammalian alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=7-68 nM) and alpha-7/CHRNA7 (IC(50)=253 nM) nAChRs (PubMed:8068627, PubMed:10545176, PubMed:15929983, PubMed:22024738, PubMed:25101833).  It also shows a high inhibition on alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) (IC(50)=11 nM) and a low inhibition on alpha-6-beta-4/CHRNA4-CHRNB4 (IC(50)>500 nM) (PubMed:22024738).  It interacts with a hydrophobic pocket between two acetylcholine receptor subunits.  In vivo, inhibits Ehrlich carcinoma growth and increase mouse survival (PubMed:32272633).  These effects are greatly enhanced when the toxin is applied with the selective 12-lipoxygenase inhibitor baicalein (PubMed:32272633).
What are the official names of this protein?
Alpha-conotoxin PnIA, Alpha-PnIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SERC_RABIT
Sequence: MDSPRQIVNFGPGPAKLPHSVLLEIQKELLDYKGLGISVLEMSHRSSDFAKIVNNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKPGRCADYVVTGAWSAKAAEEAKKFGTVNIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFVPDVKGAILVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGAAGVTVVIVRDDLLGFALRECPSVLEYKVQATSSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMKKLSTIKSQMIYEIIDNSQGFYVCPVEPRNRSMMNIPFRIGNAKGDEALEKRFLDKALELHMISLKGHRSVGGVRVSLYNAVTIEDVQKLASFMKNFLEMHQL
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, PSAT, Endometrial progesterone-induced protein, EPIP, Phosphohydroxythreonine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
Protein: RS15_BACCZ
Sequence: MALTQERKNEIIAQFRTHETDTGSPEVQIAVLTEQINTLNEHLRTHKKDHHSRRGLLKMVGKRRNLLTYLRNSDITRYRELITKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: KASA_MYCTO
Sequence: MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the elongation of long chain acyl-ACP substrates by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Involved in the initial extension of the mycolate chain and forms monounsaturated fatty acids that averaged 40 carbons in length.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 1, Beta-ketoacyl-ACP synthase 1, KAS 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRTL_STREM
Sequence: MTLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLDFNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPRLQSHQANYLYICQHCGQAYDRKRPINLAVFACGRCHGRLIEKNQS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T4HR_ZYMTI
Sequence: MAVTPYVDTSRLDGKVALVTGSGRGIGAAMAIHLANRGAKVVVNYANSVEAANKVVDEIKSRGGEAIALQADVGEVSQTTKLMDDAVAHFGQLDIVCSNSGVVSFGHLKDVTEEEYDRVFRINTRGQFFVAREAYKHLSVGGRIIMMGSITGQAKGVPKHAVYSASKGAIETFVRCMAIDCGDKKITVNAVAPGGIKTDMYHAVCKEYIPNGENLTDEEVDEYAKTWSPMDRVGQPMDIAKVVGFLASEDGEWINGKVIGIDGAACM
What is the function of this protein?
Probable tetrahydroxynaphthalene reductase; part of the gene cluster 29 that mediates the biosynthesis dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:28818040).  Catalyzes the NADPH-dependent reduction of 1,3,6,8-tetrahydroxynaphthalene (T4HN) into (+)-scytalone (By similarity).
What are the official names of this protein?
Probable tetrahydroxynaphthalene reductase MYCGRDRAFT_87994, Conidial pigment biosynthesis cluster 29 protein MYCGRDRAFT_87994.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CYB_TERNE
Sequence: MSTNLRKTHPLAKIINNSFIDLPSPSNISAWWNFGSLLGTCLILQTITGIFLAMHYSSDISLAFSSVAHITRDVQYGWLIRNMHANGASLFFMCIYLHIGRGIYYGSYLYKETWNTGTALLFLTMATAFVGYVLPWGQMSFWAATVITNLLSAIPYIGNTLVQWIWGGFSVDNATLTRFFTFHFLLPFIIMGLTMVHLLFLHETGSNNPTGLNSNADKIPFHPYFSYKDLLGLILMLAFLLTLTLFFPNFLGDPDNFTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILVLFLMPALHTSKQRTTQFRPLTQILFWSLIADLLVLTWIGGQPVENPFTIIGQMASTLYFSILLILMPIAGMIENKMLS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SODM_YEAST
Sequence: MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTVTGPLVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASRRFDAGKI
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CRLF2_MOUSE
Sequence: MAWALAVILLPRLLAAAAAAAAVTSRGDVTVVCHDLETVEVTWGSGPDHHGANLSLEFRYGTGALQPCPRYFLSGAGVTSGCILPAARAGLLELALRDGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGDVTVSWPAHSYLGLDYEVQHRESNDDEDAWQTTSGPCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAPSPALAPPLLPLGCGLAALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQAWIADAQATAPPARTEEEDDLIHPKAKRVEPEDGTSLCTVPRPPSFEPRGPGGGAMVSVGGATFMVGDSGYMTL
What is the function of this protein?
Receptor for thymic stromal lymphopoietin (TSLP).  Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5.  Also activates JAK2.  Implicated in the development of the hematopoietic system.
What are the official names of this protein?
Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2, Thymic stromal lymphopoietin protein receptor, TSLP receptor, Type I cytokine receptor delta 1.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.