PharMolix/UniProtQA huggingface dataset:
Protein: ABDH_ECO27
Sequence: MQHKLLINGELVSGEGEKQPVYNPAMGDVLLEIAEASAEQVNAAVRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: RFBF_SHIFL
Sequence: MNSNIYAVIVTYNPELKNLNALITELKEQNCYVVVVDNRTNFTLKDKLADIEKVHLICLGRNEGIAKAQNIGIRYSLEKGAEKIIFFDQDSRIRNEFIKKLSCYMDNENAKIAGPVFIDRDKSHYYPICNIKKNGLREKIHVTEGQTPFKSSVTISSGTMVSKEVFEIVGMMDEELFIDYVDTEWCLRCLNYGILVHIIPDIKMVHAIGDKSVKICGINIPIHSPVRRYYRVRNAFLLLRKNHVPLLLSIREVVFSLIHTTLIIATQKNKIEYMKKHILATLDGIRGITGGGRYNA
What are the official names of this protein?
dTDP-rhamnosyl transferase RfbF.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: CEP63_CHICK
Sequence: MEALLEGMQRNGQGSSGFLTSCEAELQELMKQIDIMVAHKKAEWEGQTQALEACLGVREQELSSARAALEEKHKEVGKLRQQLEDMEAAKQDLVREYEQQLKKFQEELARLRRSYEKLQKKQLREAREEATKRQGDDQCEMSRLSRKLEEFRQKSLDWEKQRLLYQQQVASLEAQRKALAEQSELIQTQLASRKQILESVELASRSEIQHLTSKLERANDTICANELEVERLNMRVDDLTENNRMILEDQQRVAEELRQSKKMLEVLQDEKMELRATLQSQEDFIDSSKLHQEQLQKELARVTETLHTKEILIRALEERLQEKQLSSPGLEHILLQLDVAQEKEQHLQAEVTHLEDSLVSSNARCVQLSEELAESIKELQSMEEHRAESKVEIKKLKEQLSQAEQIHRGELEGMRKEILRLTQELHQRDITIASAGGSTSDLEQRLRMEIERAERKAVEHRMILVQLETLKLENRHLSEMLEKVELGVLEGKDATLRALSEDYVVELNKLKSENQQLKKDLSEAREKLELTTQSQPEGTAQQLQSEEPEPRDVQHRPTQESQHKQDEQTEKIHHKPDKTTQHHQRWKIQPLPAEIPVAVIPEASVLPTQTSRKSCVESPTLAAGALQGTDSLLLVLDDSKGFPDATSRQSNHEQESVPLCPLPTSSVGSVAARYLEEEELRSQHILECLDAHIEELKKESEKIVRHFGHQE
What is the function of this protein?
Required for normal spindle assembly.  Plays a key role in mother-centriole-dependent centriole duplication (PubMed:19182792).  Plays a role in DNA damage response (PubMed:19182792).  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:19182792).
What are the official names of this protein?
Centrosomal protein of 63 kDa, Cep63.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
Protein: PELO_SULIY
Sequence: MRILEFDEKRQAAKLHIESEDDLWILHLILEKGDKVVAKTTRDIGLGKESRRIPMTIVLKVDYTEFQEFTNRLRIHGIIEDAPERFGIRGAHHTINLDIGDEIIIIKQQWNKYALDKLKKQADKRSKIIIALVDFDEYLIAIPFEQGIKILSEKSLRSLNEEEGIIEQNALEVATELAEYVKQYNPDAILLAGPGFFKEEVAKKVNNILKNKKVYIDSVSSATRAGLHEILKRDIIDKIMSDYEIAIGAKKMEKAMELLAKQPELVTYGLEQVKNAVEMGAVETVLLIEDLLSSNNQERLAIERILEDIENKRGEIILVPKESPIYFELKNLTGILAILRFRIN
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_MYCPA
Sequence: MARKGILGTKLGMTQVFDENNRVVPVTVVKAGPNVVTRIRTPEQDGYSAVQLAYGEISPRKVNKPVTGQYAAAGINPRRFLAELRLDNPDAAAEYQVGQELTAEIFTDGSYVDVTGTSKGKGFAGTMKRHGFRGQGASHGAQAVHRRPGSIGGCATPARVFKGTRMAGRMGNDRVTVQNLLVHKVDTENGVLLIKGAVPGRTGGLVMVRSAVKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PELI2_HUMAN
Sequence: MFSPGQEEHCAPNKEPVKYGELVVLGYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNTDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPID
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.  Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6.  Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination.  May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation.  Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
What are the official names of this protein?
E3 ubiquitin-protein ligase pellino homolog 2, Pellino-2, RING-type E3 ubiquitin transferase pellino homolog 2.
What is the protein family that this protein belongs to?
Belongs to the pellino family.
Protein: Y1518_MYCTU
Sequence: MVPGDASSVVSVNPAKPLISVCIPMYNNGATIERCLRSILEQEGVEFEIVVVDDDSSDDCAAIAATMLRPGDRLLRNEPRLGLNRNHNKCLEVARGGLIQFVHGDDRLLPGALQTLSRRFEDPSVGMAFAPRRVESDDIKWQQRYGRVHTRFRKLRDRNHGPSLVLQMVLHGAKENWIGEPTAVMFRRQLALDAGGFRTDIYQLVDVDFWLRLMLRSAVCFVPHELSVRRHTAATETTRVMATRRNVLDRQRILTWLIVDPLSPNSVRSAAALWWIPAWLAMIVEVAVLGPQRRTHLKALAPAPFREFAHARRQLPMAD
What are the official names of this protein?
Uncharacterized protein Rv1518.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DNLJ_CHLP8
Sequence: MDKAKAQQEIGKLRAEIERHNRLYYLEAKPEISDFEFDKLLERLIALETEFPELVTPDSPSQRVGGGITKEFPTVIHREPMLSLSNTYSIGEVSDFCTRVEKLVAAEGGGTPEYVAELKYDGVAISLFYRDGLLVRGSTRGDGRQGDEITANLKTIPSIPLRLQSAGGSLFDAAVNGEVEVRGEVYMRKDDFERLNEERPEEERFANPRNATAGTLKLQDSAEVARRRMSFVAYYLKGHDGEAPTHLRRLEQLKCMGFMTGAAARLCKGMDEIANFIGEWSEKRWTLPYETDGVVLKLNEVGLWDRLGATAKSPRWAIAYKYPAQQAKTVLQGVVFQVGRLGTITPVAELKPTKLAGSTVSRSTLHNFDEIERLGVRIGDHVMIEKSGEVIPKVVSVVLDERPAETAEIEAPSECPVCGTKLERHEGEVSWYCPNEEGCPAQKRGRILHFASRNALDIQNLGESLVSQLVERGFVSDAGDLYSLTQEQLASLDRMAAKSAQNVLDALEKSKKQSYARLLFALGIRHVGAATARELAHACPSIDRLREMGEEELAAVPDIGPVIAASIRDFFAKPWVAAMLEKLAAAGLPMQAGEEKALVNTNFEGQSVIFTGGLERHVRQQAEEMVRERGGKIVSSVSKKTTLVVAGKEAGSKLEKAMKLGVRVIDEDEFERML
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RR16_GOSHI
Sequence: MVKLRLKRCGRKQRAVYRIVAIDVRSRREGRDLRKVGFYDPINNQTYLNVPAILYFLEKGAQPTATVHDILKKAGVFTELTLNQTKFT
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGXB_ASPFC
Sequence: MKFFALAALFASTVNSIAVDGLIPGARVIPANDVVALKKAGAYHQKHHHRRTVIIRSSSSDEDDVSADFLWGIKRANHGGRLLLQNGKKYVIGKKLDLTFLKDIEVQLDGELKFTNDVPYWQANNFYYDFQKSISFWRWGGEDIKIFGSGVLNGNGQRWYNEFAGQEILDPNNKYYRPILFVTENATRVSVEGITQLNSPCWTNFFVRTKDISFDNVFIHAYSTNASALPKNTDGFDTLNVDGLTVTNTRVDIGDDCLSPKPNTTNVFVKNLWCNGTHGASMGSIGQYPGVLDIIENVWIENVTLLNGENGARLKAWAGPDVGYGRINNVTYKNIHVENTDNPIVLDQCYFNINATQCAAYPSRVNFTNIVFEDIYGTSSGKRGKVVADLTCSPNAVCSGIRLKNIHLTSPAGSPPVIVCDGIQGDIGVECQSSSNSTTKRSVDLARSLKYRA
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase B, Galacturan 1,4-alpha-galacturonidase B, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECF_SALPK
Sequence: MSLTRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQPGRVIRHEQEAFVLHGRLQGEEREMSIGLTKDKQGDSKVRIDGTDGHKIAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQRNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTFSFQRGWEKETDYADVLERSFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_SALPC
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGIDPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_SHEB5
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWEKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGMMRSREFLMKDAYSFHLDVDTMNETYEAMYNAYSNILTRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPVPTEPRGAATEELRLVDTPNAKTIAELVEQFDLDITKTVKTLIVVGASEATPLVALIVRGDHELNEVKADKLDLVASPVEMAPEALIRDAIGAGPGSLGPIGLNIPIVIDHSVSVMSDFAAGANVDDKHYFGINWERDLPTAQVADIRNVVEGEPTPDGSGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIIWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLNEAGIDVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDIPFDQLLDLLKNAVKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y9443_DICDI
Sequence: MNKFLNLIGLAFVLVLCAFSCSNAEEMGSCSSWHVAQKGYTCYDMATSCKVTLDQFMRTNKLDNNACKLVQIGRKYCCN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289443.
What are the subcellular locations of this protein?
Secreted.
Protein: YD215_YEAST
Sequence: MKTPPNQEKNNEKISLLFSSQRLTIDVHPSSVYHIVLSSNNADRHQVTLSFTARSRMMPLTRARPFGNHSSMFRMFLDAMVILAVASGVSLPPQLPGRRSHNASTPGAKKPGKDHGAMVSEFPANGVITPVYFPLRW
What are the official names of this protein?
Uncharacterized protein YDR215C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYE1_ROSDO
Sequence: MTTTRFAPSPTGYIHIGNLRTALMNYLIARKAGGTFILRIDDTDPERSKEEYVDGIKQDLEWLGLHWDRIERQSLRLDRYAQAADKLRDMGRFYEAFETPTELDLKRKKQLNMGKPPVYDRAALELSDAEKDALRAERGAGVWRFKLERERIEWADGILGDISIDAASVSDPVLIRGDGQILYTLASVVDDTEMGVTNVVRGSDHVTNTATQIQIINALGGTVPDFAHHSLLTGPQGEALSKRLGTLALRDLRENGVQPAALLSLMARLGSSDPVELQTDMADLIEGFDISRFGSAPTKFDADDLYPLTARYLAGLPLADVAGDLSAAGVPDDMAAQFWDVTRENITTLKDIGPWWTLMRDGAEPQIDDEDREFVAEALALLPDGPFDATTWGTWTAAVKEKTGRKGRALFMPLRKALTGQSHGPDMSGLMPLLQVVKARR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_WOLWR
Sequence: MTERSLNNLILASSSKRRIALLKQINIEPGLILPADIDEAPLKKELPKDYSIRMAKSKAEKIQSSNPNYFVLGVDTVVACGRRILLKAENVEQAEKCIRLLSGRRHRVYTSVCLLTPDQSKQHIRTVVTIVKFKRLSEQEIKYYLASEEWKNRAGGCNIQGLAGVFVLFLRGSYSSVIGLPLHETYCLLSNYFNFNLY
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_RHOOB
Sequence: MSTMYAASREALTQTRAALSSALGSVSAGAATAAAAQIGAELFSVVEILDEQRTLRSALSDTSTTGSVREGLAERVFGSKVSAETLAVVKSAAGQDWSVTSDLLNSLVLLGRESLLKAAADQGQLDAVEDELFRLGRIVAGDPKLEQSLSDRSVPAKGKRDLLSKLLYGKVTAVSEALATQAVGRLKNSAPADAFDELSNLAAAQRKAVVAKVRSAAPLSSEQSDRLTATLTRTYGKPVTVHVEVDPELLSGLVVRVGDEVIDGSGAGRLAALRKSLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DMRT1_ALLMI
Sequence: SLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSATELFVKKENSGGSSCLLLESSSPTHSTSTVTTVSTSPSEGRMLIQDVPSITSRGHLESTSDLVV
What is the function of this protein?
May be required for testis development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOD4A_XENLA
Sequence: MHLYFYCLILLFVPGGNSLGINSYLKHMSNKPQDHVNRTKTVDSKDLAALPLSSYMLNLYQSFHHSELNHGTEGAPSLPSNHRADIIRSLAAKSFDHGGSRWTLVFDFSSLSQEEEHQLAEVRFDFRAFEGAISAEMEVMVDFLHQSSSCQSISGWCQSYLYVGSLTGTLRSRSSDTWVTFEATDIIHKWFERNEKGKSRYEDREKQLKKLPRAKSAERRYQQQNTEDQQIVMMVYSNISKKERLSGTATLLQDAAHSKYLVVMPGIQTIAHTRRHRRSHIFKEHVMGMKHVPPADSSRTLCRRVDFFVDFKQIGWDSWIIHPMKYNAYRCEGECPSPVNESVKPNNHAYMQSLLNYYVKGKAPEVCCVPIRMSSLSMVYYDHDDIAFQNHEGMIVEECGCQ
What is the function of this protein?
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos.  Plays a role in mesoderm formation and may be required for neural development.
What are the official names of this protein?
Nodal homolog 4-A, Nodal-related protein 4-A, Xnr-4, Xnr4.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAP_HHV8P
Sequence: MPVDFHYGVRVDVTLLSKIRRVNEHIKSATKTGVVQVHGSACTPTLSVLSSVGTAGVLGLRIKNALTPLVGHTEGSGDVSFSFRNTSVGSGFTHTRELFGANVLDAGIAFYRKGEACDTGAQPQFVRTTISYGDNLTSTVHKSVVDQKGILPFHDRMEAGGRTTRLLLCGKTGAFLLKWLRQQKTKEDQTVTVSVSETLSIVTFSLGGVSKIIDFKPETKPVSGWDGLKGKKSVDVGVVHTDALSRVSLESLIAALRLCKVPGWFTPGLIWHSNEILEVEGVPTGCQSGDVKLSVLLLEVNRSVSAEGGESSQKVPDSIPDSRRQPELESPDSPPLTPVGPFGPLEDASEDAASVTSCPPAAPTKDSTKRPHKRRSDSSQSRDRGKVPKTTFNPLI
What is the function of this protein?
Plays an essential role in the viral lytic DNA replication by acting as the polymerase accessory subunit.  Stimulates the viral DNA polymerase activity and appears to function with it as a holoenzyme.  Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template (By similarity).
What are the official names of this protein?
DNA polymerase processivity factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase accessory subunit family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: UP05_GINBI
Sequence: NNQLNASHK
What are the official names of this protein?
Unknown protein 5.
Protein: ARCS_METJA
Sequence: MLEPIAYDIGRLCKEEDKELTPKLIDIDVIGLSQEKIFYGIMTPFRCPNSKSIYELRKSYVKADGIKMPFDTFRELTSIFKKSFIGTVKYKGNVFKYQILNFGKHVDLIELEDADLYIIADGRRLIERKELQIIPKIREKISPNSAIYSPAVFPWEIPLLAYIGVDYFDDSLAKLYASMGYKFTKNRAVKVDSFSFEELYNNNKKVYEEILEEVRIAIKNGFLRNVVEETAVSHPYLWANYRRYEPDLRNIPLSKENKIIVTTNINIPEVKKYLERLDNYEPYSNIIVLLPCSSKKPYSISQSHQKFIKAIKSAKVVVEEVILTSPYGLVPRALERLVNYDIPVTGEWSFEEIELINNCLKNFLKKVKEKFDDYIVIAHLPEHYLEILELDDIVITSKGNPTSEEALKNLTDTLKKYKELTKSKDINKKGQRIHNIQQLAEFQFGINFIPNEIFINHKGQIFTKINNKNQQIASINPKNGLLILTLSGGELLWNSGGKDINYIEVNYEIKKGSLFPPGFVDCNENISYNDEVVLIKDDTFLGIGRALMSGFEMKKAKHGALVNIRNVKS
What is the function of this protein?
Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA.  Catalyzes the conversion of 7-cyano-7-deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group.  Can use either glutamine, asparagine or ammonium as amino donor.
What are the official names of this protein?
Archaeosine synthase, Glutamine:preQ0-tRNA amidinotransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine synthase type 1 family.
Protein: YR7C_ECOL6
Sequence: MAIEGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFIKDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLFPRRLTMPN
What are the official names of this protein?
Uncharacterized protein ORFC-like in prophage region.
Protein: NAGR_RALSP
Sequence: MDLRDIDLNLLVVFNQLLLDRSVSTAGEKLGLTQPAVSNSLKRLRAALKDDLFLRTSKGMEPTPYALHLAEPVIYALNTLQTALTTRDSFDPFASTRTFNLAMTDIGEMYFMPPLMEALAQRAPHIQISTLRPNAGNLKEDMESGAVDLALGLLPELQTGFFQRRLFRHRYVCMFRKDHPSAKSPMSLKQFSELEHVGVVALNTGHGEVDGLLERAGIKRRMRLVVPHFIAIGPILHSTDLIATVPQRFAVRCEVPFGLTTSPHPAKLPDIAINLFWHAKYNRDPGNMWLRQLFVELFSEA
What is the function of this protein?
May regulate the expression of the naphthalene (nagA-F) and salicylate (nagG-M) metabolism genes.
What are the official names of this protein?
HTH-type transcriptional activator NagR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: COPS_PSEUB
Sequence: MKPGSLTLRLSLLFVVAVAAVLIIVGVAFNELSRHHFRALDAQALGEKLEAITQIAKESGANPELLKARWHTLLGAHPDLSAVFLKTDGTPFFAEPPQSAVPSLAQATQRDGVWEWEKEGRMFRALTASVSLPTASPPLTAWLVLDVTTHMHFFAMLERWFWGVLLASTVLSAALGWLVAKNGLRPVARVTQTAASMSAGSLKERIPLEPVPDELRALITAFNSMLGRLDDSFMRLSNFSADIAHELRTPISNLRTHTEVILAKKRAPEVYEENLSSNLEELNRLSGIIDGMLFLAKSDNGLIVPEAVELDLRTVISKLFGYYEFLAEDKGIQLQASGNASIFADSVMIDRVVSNLLSNALRYTSSGETIKVSIHDHGGRVELRLENPGPEIVPQHLDRIFDRFYRVDPARREGRECGAGASDCPVLDASAWRHYLVYIPRGPNDLHPHLHAIACPTNLTCRPDSLGTAKPGHTRLGEHETGCHCAG
What is the function of this protein?
Member of the two-component regulatory system CopS/CopR.  Involved in the activation of copper resistance gene operon copABCD.  Specifically recognizes or transduces a signal only in response to copper.  This would lead to phosphorylation of CopR in the cytoplasm.  CopS/CopR may also regulate chromosomally encoded genes.  May also be involved in basic copper metabolism.
What are the official names of this protein?
Sensor protein CopS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOB_STRE4
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVRNTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVGRYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKFVYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIVWLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIADGPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL11_PHOLL
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYSDRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKVTSAQIREIAETKAADMTGASVDAMMRSIEGTARSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DDDQ_RUEPO
Sequence: MTQTDPAFQNLLAEFQALHAREPALAGFVALPDSLTPQPVTPVRIPPAALMESDPDLTTTAYAAIRDAFIAAGAVAQWRLTYQGSRLGADFMDRFACYCLIGEGGPFASDSLAAYVVYMPAGLYYPFHQHPAEEIYFILAGEAEFLMEGHPPRRLGPGDHVFHPSGHPHATRTYDRPFMALVLWRGDLETAPVLTYPEGEI
What is the function of this protein?
May act as a dimethylsulfonioproprionate (DMSP) in vitro, releasing dimethyl sulfide (DMS).  DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:20880330).  The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethylsulfonioproprionate lyase in vivo (Probable).
What are the official names of this protein?
Dimethylsulfonioproprionate lyase DddQ, DMSP lyase.
What is the protein family that this protein belongs to?
Belongs to the non-heme iron-dependent dioxygenase family.