PharMolix/UniProtQA huggingface dataset:
Protein: PNP_CERS4
Sequence: MFNVTKKSIEWGGETLTLETGKVARQADGSVIATLGETSVMANVTFAKAAKPGQDFFPLTVHYQERYYAAGKVPGGFFKREARPSEKETLTSRLIDRPIRPLFVDGFKNEVLLIVTVLSHDLVNEPDIVAMIAASAALTISGVPFMGPIGAARVGFAGGEYVLNPDVDDMQKLRENPEQRLDLVIAGTKDAVMMVESEAYELSEAEMLGAVKFGHEAMQPVIDMIIDFAEEAAHEPFDFSPPDYAALYAKVKSLGETQMRAAFAIREKQDRVNAIDAARAAIKAQLSEAELADENLGTAFKKLESSILRGDIINGGARIDGRDTKTVRPIISETSVLPRTHGSALFTRGETQALVVTTLGTGEDEQIIDALHGNSRSNFLLHYNFPPYSVGEVGRFGPPGRREIGHGKLAWRALQAVLPAATDFPYTIRVVSEITESNGSSSMASVCGGSLSMMDAGVPLKAPVAGVAMGLILEDDGKWAVLTDILGDEDHLGDMDFKVAGTENGITSLQMDIKVAGITPEIMEQALAQAKDGRMHILGEMSKALSSANSFSAYAPKIETLTIPTDKIREVIGSGGKVIREIVETSGAKVDINDDGVIKIASNDQAAIKKAYDMIWSIVAEPEEGQIYTGKVVKLVDFGAFVNFFGKRDGLVHVSQIANKRLTHPNEVLKEGQEVKVKLLGFDERGKVRLGMKMVDQETGQEIQPEKKEKEEAGEA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL79_SHV21
Sequence: MDILGRFVRESKKMSPGLKTIMEKVLRGQSLNSFHSEELRFLHLVICKMYDFCLNVYILKESIINTGTRDNEVLSRKVPVEIWKIMYDACKSIGVENTMLIDDSSRGQLWLHLNSNIDLLQGMSQFIFSKLGIKHFVKISPQNITDGNYLFNLGSVLPYRLILILQFCLIFWGKEQEEAWVRFFTGKIFMLYLLITGHLLIQKTFILQAASTGYCGPLEIIGDDLRSYLGIHTYMTNDLQHIPSLDLLFIFNNNFY
What are the official names of this protein?
Gene 18 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL79 family.
Protein: CYSN_SALDC
Sequence: MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: COAE_BRUSU
Sequence: MIVLGLTGSIGMGKTTAAGMFAEAGVPVYSADDAVHRLYSGRAAPLIEATFPGTVENGIVNREKLFKAVIGQPEAIKKLEAVVHPLVREEEDAFRREAEKSGAAIALVDIPLLFETGAEKRVDKVVVVSAPADIQHTRVLARPGMTQEKLKAILVRQIPDAEKRSRADFVLDTSGSFDDLRRQIAEIITGLSGKPAAATR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMON2_CAEEL
Sequence: MFVLAIVFAFVFIPSSSSVTCDFKNELVSMNWNVKNNKIQIHFEHNNLTENRWTSIAFGDGPGMNNLESIIFSRREDNVITTNSGYTPKKKKVVVDDVSYVTVNDVQITGNKLKVTVSRPLGPAGPRNFSLDQCLNWMVVPGGSLSNGKFKKHHGKIFFIKDVCAAKCTAERIQRINSNKAL
What are the official names of this protein?
DOMON domain-containing protein Y73F4A.1.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHI_PROM4
Sequence: MAGFFQQVTEYTRNAISAGKYLLQGLAVTFDHMGRRPITVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELAAFDRHSLNFDNVALGRLPTSVTTDPSVKSLREFAYLPEKVFDPHEVLPTEPRAGKLPEEVLDWMKAETTDKKVMESSSNNFKEGDKP
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: DEAF1_RAT
Sequence: MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPSPDEAAAAAAFAEVTTVTVANVGSSADNVFTTSVANAASISGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKENELPTTPVKKDSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVTQARMQVDAERKEQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQSASVTVQADDVHVEESVIEKVAV
What is the function of this protein?
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene.  Down-regulates transcription of these genes.  Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'.  Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction.  When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.  Regulates epithelial cell proliferation and side-branching in the mammary gland.  Required for neural tube closure and skeletal patterning.  Controls the expression of peripheral tissue antigens in pancreatic lymph nodes.  Transcriptional activator of EIF4G3.  May also involved in behavior (By similarity).
What are the official names of this protein?
Deformed epidermal autoregulatory factor 1 homolog, Nuclear DEAF-1-related transcriptional regulator, NUDR, Suppressin.
What are the subcellular locations of this protein?
Nucleus. Secreted. Note=Secreted in some cell types.
Protein: RIMP_BACP2
Sequence: MSKKVVDVVSEMVQPILDGLQLELVDVEFVKEGQNWFLRVFIDSDKGVDIEECAKVSEALSEKLDEADPISQNYFLEVSSPGAERPLKKKADFEKALGKNVFMKTYEPIDGEKAFEGELTSFDGEIATVTVKIKTRKKEINIPYEKIANARLAVSFN
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_STRU0
Sequence: MTLSQLKNCQIITALVTPFHADGSINFKALPELIEHLLNNHTQALLLAGTTAESPTLTHEEELELFSEVQRIVNGRVPLIAGIGTNDTRDSVDFAKEVANFGGFAAGLAIVPYYNKPTQEGLYQHFLAIAEASSLPIIIYNIPGRVVVDLHPDTLLKLAQHPNIIGVKDCTNLDHLAYIIENKPEDFLIYTGEDGQIFHAMNLGADGVISVASHTNGSEIFEMINHITNGRIKEAAQIQRRFLPKVNALFSVSSPAPVKAVLNYLGFNVGPLRLPLVACTRQEADAIINIVLDKAPKEYVTKGVLRPDY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_UREU1
Sequence: MKYNVMFFGTPEIAKIVLETLFNMPEVNLIGVVSQPDSHFDRKKNVVYSPVKQFCLDHDIKLFQPQKIKEIEEEIRSLAPDIIITCAFGQFINQGIIDIPKYKIVNVHASLLPKLRGGAPIHYAILNGDLQTGITLMHTIKKMDAGNILFQRSLAINEQTTTKILTLELANLGALMIKEHFLELVKSDLVGIQQDENDVSFAYNIQKNQNIIDFNKPAFFVNRFVNAMYDKPIAIMEYNDVLIKVHQIKITNQKSTQKPGTIAISKHQIFVSTQDFNVELLLIQLPNKKPLAPKALLNGKNPFSN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: AROA_CROS5
Sequence: MSKSIINLQSVENQQILSITPPNTGLSLQGTLQIPGDKSISHRALMLGAIAEGETIIAGLLLGEDPRSTAECFRAMGAQISPLNSEKVTIQGIGLGKLQEPLDVLNAGNSGTTMRLMLGLLASHPDRLFCVTGDASLRSRPMSRVIQPLQDMGANIWGRKNNTLAPLAVQGKSLKPIHYHSPIASAQVKSCILLAGLMTDGKTTVTEPALSRDHSERMLQAFGATLDIDSQTNSVTINGHPKLIGQTVIVPGDISSSAFWLVAASIVPGSELLIENVGINPTRTGILEALEMMGADITLENKRILTGEPVADLRVKSCQLKGCTIGGNIIPRLIDEVPILAVAGIFATGKTIIKDAAELRVKESDRLAVMASELTKMGAKITELPDGLEITGGTPLKAAEVDSYTDHRIAMSLAIAALNAKGKTIINRAEAAAISYPKFVETLQQVCGDSN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_LEPIN
Sequence: MNCKILFRKELNDSECELSLLLVGDSDMKEINRLRRGKDKTTDVLSFPLEFDFSPLQKILPKNTSSDQKMFPPIALGEIVISIDTLQKQAKEIGHSEKDEFYRLLVHGFLHLLGYDHERGDKEEHIMKLKEDECLEILQGL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUB_ECO57
Sequence: MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEVTPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGVQLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNNG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: VGB_MYCSJ
Sequence: MSLIREIAGGPYALAAGPDGAMWVTLVHDGAIARVGADGAVDRFPVADGSRPSLISAGPDGALWFTRNGDDRIGRLTTAGELTEFPLSEGSAPFGICAGADGALWFTEMGSGGIGRITVDGETSGWASVGGTPSMITRGPDDAVWFTLNQGNAIGRLHPRDGVTMRELPTRGAGPVGITATHDDAIWFTEILADKLGRIPLDGALQEIDLPGKPHAVVADPSGGVWVSLWGADRLARVSADGDIETFDLPPGSEPHGLAFGPDGGLWVALESGFVLRMPD
What is the function of this protein?
Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
What are the official names of this protein?
Virginiamycin B lyase, Streptogramin B lyase.
What is the protein family that this protein belongs to?
Belongs to the Vgb family.
Protein: GLMM_DINSH
Sequence: MARKLFGTDGVRGTANTAPMTAEMALRLGAAAGRYFRRDQSAAHRVVIGKDTRLSGYMFETALTAGFTSTGMNVLLLGPIPTPAVALLTQSMRADVGVMISASHNPADDNGIKFFGPDGYKLSDAAEEEIEEILAGDIRPAQAPNIGRAKRIDDGLGRYIERAKRTFPAHLRLDGLKVVVDCANGAAYKVAPAVLWELGADVIPVGVSPNGRNINRDCGSTAPQTAAEAVVSHGADVGICLDGDADRVMILDENGELADGDQLMALFATRWAAQGLLRDNTLVATVMSNLGLEYYLNDLGLKLVRTAVGDRYVVEAMRKGGWNLGGEQSGHIVMLDHGTTGDGLMAGLQFLAEMVQQGRSASELKHSFTTVPQRLENVRFGAGQDPLAAASVKSAIAAAEAQLSGKGRLLIRKSGTEPLVRVMAECEDEAMLTSVVGEVVAAVEAAC
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DER_STACT
Sequence: MTKPVVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNVIDTGGIELTDAPFQTQIRAQAEIAIDEADVIIFMVNQREGLTQTDEMIAQMLYKTNKPVVLAVNKVDNPEMRTDIYDFYALGFGEPFPISGSHGLGLGDLLDEVANNFKDEEDDDYDEDTIKLSLIGRPNVGKSSLVNAILGEDRVIVSNIAGTTRDAIDTEYSYEDQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVLDAEEGIIEQDKRVAGYAHEEGKAVVIVVNKWDTLDKDSKTMKKFEDKIRQEFQFLDYAPIAFVSAKEKQRLRTLFPLIKEASENHKKRVQSSTLNEVITDAISMNPTPTDKGRRLKVFYATQVAVEPPTFVVFVNDAELMHFSYKRYLENQIRDAFGFEGTPIRIIPRKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GSA_PSEPW
Sequence: MSRSESLFAQAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVVDEDDKRYVDYVGSWGPMILGHGHPQVLDAVRNQLQHGLSYGAPTAMETEMADLVCSLVPSMEMVRMVSSGTEATMSAIRLARGYTGRDAIIKFEGCYHGHSDSLLVKAGSGLLTQGVPSSAGVPADFAKHTLTLPFNDIAAVEKTLAEVGQTVACIIVEPVAGNMNCVPPAPGFLEGLREQCDKHGVVLIFDEVMTGFRVSLGGAQGYYGITPDLSTFGKIVGGGMPVGCFGGKREIMGCIAPLGPVYQAGTLSGNPLAMAAGLTTLKLISRPGFHDELSDFTSRMLDGLQQRADAAGVPFVTTQAGAMFGLYFSGADDIVTFDDVMASDAERFKRFFHLMLDGGVYLAPSAFEAGFTSIAHGDKELQITLDAAERAFAALK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_AGRFC
Sequence: MILFPAIDLKDGECVRLKLGDMEQATVYNEDPGAQAKAFEDQGFEWLHVVDLNGAFAGETVNGAAVDAILKSTKNPVQLGGGIRTLDHIEAWLSRGLARVILGTVAVRDPVLVIEACKRFPGQVAVGIDAKGGKVAVEGWAEASELGIIELAKRFEGAGVAAIIYTDIDRDGILAGINWASTLELADAVSIPVIASGGLASIDDIKRMLQPDAAKLEGAISGRALYDGRIDPTEALDLIKAAKEVRA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_SYNY3
Sequence: MLSGSAQLKLLQLVSPTLPVGAYNYSEGLEWLIERGNITNADTLGAWITQELCRGSITVDTAIMVRAHRLAGQMPKTDILPSPTLKHLSYWNQWLTATRESRELREQSLQMGGSLRKLLLDLEPTVQSWFEPIPPTEPCNYAIAFGLGAAFWGIDLHQSGLGYLHSWANNLISAGLRLIPLGQTAGQKLLLHLTPTILHQWQQILLLGDDDLYSCSWGLALASMGHESQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNC_YERPE
Sequence: MSLNEPIKKVSIVIPVYNEQESLPALIDRTTAACKLLTQAYEIILVDDGSSDNSTELLTAAANDPDSHIIAILLNRNYGQHSAIMAGFNQVSGDLIITLDADLQNPPEETPRLVHVAEEGYDVVGTVRANRQDSLFRKTASRMINMMIQRATGKSMGDYGCMLRAYRRHIVEAMLHCHERSTFIPILANTFARRTTEITVHHAEREFGNSKYSLMRLINLMYDLITCLTTTPLRLLSLVGSAIALLGFTFSVLLVALRLIFGPEWAGGGVFTLFAVLFMFIGAQFVGMGLLGEYIGRIYNDVRARPRYFVQKVVGAEQTENNQDVEK
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMK_SHISS
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: RS3_STRA3
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINKELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINIIEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TRDC_HUMAN
Sequence: SQPHTKPSVFVMKNGTNVACLVKEFYPKDIRINLVSSKKITEFDPAIVISPSGKYNAVKLGKYEDSNSVTCSVQHDNKTVHSTDFEVKTDSTDHVKPKETENTKQPSKSCHKPKAIVHTEKVNMMSLTVLGLRMLFAKTVAVNFLLTAKLFFL
What is the function of this protein?
Constant region of T cell receptor (TR) delta chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:28920588, PubMed:23348415).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor delta constant.
What are the subcellular locations of this protein?
Cell membrane.
Protein: YQHA_SALA4
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMPA_PSEAI
Sequence: MKAQKGFTLIELMIVVAIIGILAAIAIPQYQNYVARSEGASALASVNPLKTTVEEALSRGWSVKSGTGTEDATKKEVPLGVAADANKLGTIALKPDPADGTADITLTFTMGGAGPKNKGKIITLTRTAADGLWKCTSDQDEQFIPKGCSR
What are the official names of this protein?
Fimbrial protein, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: TAGH_ENTFA
Sequence: MEKELKVRTKLLTKEYSLAQTRIDKLKTLFSVFQNKVPTFWALKGVSLDVYSGETIGIIGLNGSGKSTLSNIISGITPQTSGELEINGEVSIISIGAGLNNNLTGRENIRMKCLMLGEKNKEIDAKIDDIIEFSELGVFIDQPVKTYSSGMRAKLGFSIAVHQNPDILVIDEALSVGDQTFYNKGLKKMLAFKEQGKTIFFVSHSIQQVEQICDRVAWMHYGDLRAFGETKHILKEYRAFLHRYNHFTEPQKESYQRDGKAKQRNFSLEQLQETILEKANQQVGSRRTTKEVIKFTTKNKIGDKMTLGTKSLLILLLCMIFYVSLTFVKGISLTTAFIHPAETIQRIFVPEKVAGKDTNAVKTTKTKPASTKESRQQEEVQPSPTNVPENNNSEQAVSTYTVEVGDSVSLIAENHGLTIEQLQTLNPEIIEVPIYPGQVLKLKEVTE
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TUSA_CROS8
Sequence: MTDLFANPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIVADDPATTRDIPGFCRFMEHELVASQTETLPYRYLLRKNQ
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_MYCA9
Sequence: MARRPRPAGSEPDSGIPHIVELVRSTIPPIHPAGLPFIAGGLGLAGLGVRNRWVRGTGLALAGACAGFFRHPPRVPPNRADVVVAAADGQVCLVDRAVPPPELGLPAEPLPRISIFLSVFDVHVQRVPVAGEATAVIHRSGQFLSADRAEASVANERNSVQIRTRTGHDVIVVQIAGLIARRIVCHAKVGDQLSIGDTYGLIRFGSRVDTYLPEGSKILVQQGQRAVGAETVLAELP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.