PharMolix/UniProtQA huggingface dataset:
Protein: DENR_BOVIN
Sequence: MAADISESGGHDCRGDQRSNTKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK
What is the function of this protein?
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon.  Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Density-regulated protein, DRP.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: RPOA_BORPE
Sequence: MSTQGFLKPRSIEVEPVGAHHAKIVMEPFERGYGHTLGNALRRILLSSMTGYAPTEVQMTGVVHEYSTIAGVREDVVDILLNLKGVVFKLHNRDEVTLVLRKNGAGAVVASDIELPHDVEIINPDHLICNLTDAGKIEMQVKVEKGRGYVPGNVRALSEDRTHTIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVLDIETNGVISPEEAVRQAARILMDQISVFAALEGAGDAYEPPVRGTPQIDPVLLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLAARGLTLGMKLENWPPLGLERP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: Y751_TREPA
Sequence: MNRPLLSVAGSLFVAAWALYIFSCFQHGHVPPRRIPPHDTFGALPTAALPSNARDTAAHPSDTADNTSGSSTTTDPRSHGNAPPAPVGGAAQTHTQPPVQTAMRIALWNRATHGEQGALQHLLAGLWIQTEISPNSGDIHPLLFFDREHAEITFSRASVQEIFLVDSAHTHRKTVSFLTRNTAISSIRRRLEVTFESHEVIHVRAVEDVARLKIGSTSMWDGQYTRYHAGPASAPSP
What are the official names of this protein?
Uncharacterized protein TP_0751.
Protein: RL1_STRPI
Sequence: MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQGVGIKVDVNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CCR4_CRYNJ
Sequence: MFYPHHQSQQSTTTNPSKHHDSQDVRLPGTSSWSRHPSHPSFTPSLPMPSPSGYPPLGSGYPPGGHHHPNVNVHSGIHGPHPSFGSGMGGNGGMGHGQGFGMGMFQNGVQTSPPRGEPVPMTSHWQTQMMRAEASRSASSPHHRARAAAISSRATNKPSAVPIVDPNNRPSSSYGTNGLHRKNASSVFNGEPTGTPPLSDPSLTPAQNPAEPATPAPVAGQTESKDEEKPNEPWTGLDLGGIRLKRLSTALFSFTHVTSLYINHNALTSIPSAISSLRQLTLLDATGNELSTIPSEIGVLSKLKDLLLFDNNLTTLPFELGTLYQLDCLGIDGNPMNADYRKKLVEDGTRGLITYLRDHAPPPPPPPERQWIDLETDVDTPTSGKQESFSVLTYNILCASFAPATTYSYTPSWALDWDYRKRLLLEEIVTASADVVCLQEIDCKQYADYFYPMLKKEGYEGQHYPRSRAKTMSVDEQKLVDGCATFWKEEKFRLVETQVIEFNQLALQKTDMRTEDMFNRVMSRDNIAVVAALEFRASGGRLLVANSHIYWDHRYRDVKLVQIGMLMEELEKIVEQFSRYPVKLDTDPEYNNGKPPKYERSEKGRDIPLIMCVDLNSFSGSAVYDYLSSGSIPGDHEDFMSHLYGRYTASGLKHHLGLRSACAGIGEMRMTNFTPTFAAAIDYVFYTPRTMKVTSVLGDVDKAYLDKTVGFPNAHFPSDHIPVFTQFRIKGHLDPLPLNGDPYH
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL2_DECAR
Sequence: MALVKVKPTSPGRRGVVQVVNASLHKGKPFAALVEAKSGNAGRNNNGRITVRHQGGGHKQAYRVIDFKRNKDGIPAKVERLEYDPNRTANIALLCYADGERRYIIANKGMVVGQPIMSGSEAPIKSGNALPIRNIPVGTTICCVEMLPGKGAQLARSAGTSVQLLAREGTYAQIRLRSGEVRRVHVECRATIGEVGNEEHNLRKIGKAGAMRWRGVRPTVRGTAMNPVDHPHGGGEGRTGEGRVPVNPWGQPTKGYRTRSNKRTNSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TRHO_RHILW
Sequence: MTDSLTHTSPFLVAALYHFVSVPRFENLQALLQTLCEQSGVKGTLLLAHEGINGTIAGPDAGIAAVLSFLRAQPEFSGLEHKESRASKMPFLRMKVKLKKEIVTMGVEDIDPNKVVGTYVAPQEWNALISDPDTIVIDTRNDYETAIGTFRGALDPKTKTFREFPDWVRSNSGLHNKPKIAMYCTGGIRCEKATAFMKAEGFDEVYHLKGGILKYLEEVPQEESLWDGACFVFDERVSVEHGLKEGEHRLCHACRNPITAEEITSPLYEEGVSCSHCYDTRTEEDRLRYRQRQHQIALARKRGQRHIGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y2063_AQUAE
Sequence: MSITHLMRQQVEELFKRFLEKTGLSEEATVYAVFIPKEEEVDEESVDVFEQRVNPKDAESVENFVSRLTKVALENDVKELKLYALVLDRDGETLIIAREENPEADEVIKELIERMKEEV
What are the official names of this protein?
Uncharacterized protein aq_2063.
Protein: SBT22_ARATH
Sequence: MRRVLMVNFGVLLLFCFGVLSNSFGQDNGGDSDINSTTAVYIVTLRQASSLHLFQQEAEEVKRVRDQSKHGDTSKFTRPKLQPRNISRSRYWRSRRSAIAQAHDSLLRNALKGEKYIKLYSFHYLINGFAVFVSSQQAETLSRRREVANIVLDFSVRTATTYTPQFMGLPKGAWVKEGGYETAGEGIVIGFIDTGIDPTHPSFNGTDTSQRQYPIPNHFSGVCEVTPDFPSGSCNRKLVGARHFAQSAITRGIFNSSEDYASPFDGDGHGTHTASIAAGNHGVSAVVSGHNFGSASGIAPRAHISVYKALYKSFGGFAADVVAAIDQAAQDGVDILSLSITPNRRPPGVATFFNPLDMAMLSAVKAGIFVVQAAGNTGPSPKSMSSFSPWIFTVGAASHDRDYSNSIVLGNNVSIPGVGLALRTDEGKKYTMISALDALKNKSSVVDKDMYVGECQDYGSFDKDVIRGNLLICSYSIRFVLGLSTIKQALAVAKNLSAKGVVFYMDPYVLGFQINPTPMDMPGIIIPSAEDSKVLLKYYNSSLVRDGTTKEIVRFGAVAAIAGGQNANFSNRAPKIMYYSARGPDPQDSLFNDADILKPNLVAPGNSIWGAWSSAATESTEFEGESFAMMSGTSMAAPHVAGVAALVKQKFRKFSPSAIASALSTTSVLFDNKGEAIMAQRAYANPDQTISPATPFDMGNGFVNATAALDPGLIFDTSFEDYMSFLCGINGSAPVVFNYTGTNCLRNNATISGSDLNLPSITVSKLNNTRTVQRLMTNIAGNETYTVSLITPFDVLINVSPTQFSIASGETKLLSVILTAKRNSSISSFGGIKLLGNAGHIVRIPVSVTVKIASKQ
What are the official names of this protein?
Subtilisin-like protease SBT2.2, Subtilase subfamily 2 member 2, AtSBT2.2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FFSE_ASPFV
Sequence: MTGPPGNPAFATIHEFFPGNTFYNFECLRILSTAPYGGCDPAEFLTAIAAIKPSDPETWATAWSHAASQAERIAEDALARGDTLAARDAFLRASSYTRASGYMRINGPTLDRHDPRALPVARKTQALFRKALPFLDCDARIVDIPYRPTQYSKPVSLPGYVYIPSPQNRLPDGKIPVLLNTGGADSVQEELYYIHPQAGHARGYAVITFEGPGQGIVLREKGLYMRPDWEVVTGQVLDWLEGYAATLQQEEGLTLDLSRIAVVGASMGGYYALRAASDPRIKACLSIDPFYDMWDFGTRHISGLFMAAWTGGWVSDATIDRVIGAGMYLNFQLRWEVGVTTAFWGIESPSRILREMKRYSLQGGFLARVQCPVFVSGAGKSLYFDTEEHTMRVFGDLKHLGERRRTLWMPSRPEEGGLQAKIGAFGLVNTKAFGFLDGVFGVKRVLEAET
What is the function of this protein?
Hydrolase; part of the gene cluster that mediates the biosynthesis of the cytotoxic leucine-containing cytochalasans, including aspochalasin C, aspochalasin E, TMC-169, flavichalasine F, aspergillin PZ, aspochalasin M and flavichalasine G (PubMed:32913332).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS ffsA that utilizes 8 units of malonyl-CoA to iteratively assemble the octaketide chain before addition of L-leucine by the C-terminal NRPS modules (PubMed:32913332).  Because ffsA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase fssC (Probable).  The methyltransferase (MT) domain of ffsA catalyzes the alpha-methylation at C10 and C14 using S-adenosyl-L-methionine as the methyl-donating cosubstrate (Probable).  Reduction by the hydrolyase ffsE, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ffsF then yield the required isoindolone-fused macrocycle (By similarity).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase ffsD, the FAD-linked oxidoreductase ffsJ and the short-chain dehydrogenase/reductase ffsI, are further required to afford the final products (Probable).
What are the official names of this protein?
Hydrolase ffsE, Cytochalasans biosynthesis cluster protein ffsE.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. FUS2 hydrolase family.
Protein: DEFB1_HUMAN
Sequence: MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).
What are the official names of this protein?
Beta-defensin 1, BD-1, hBD-1, Defensin, beta 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
Protein: KATG2_MYCVP
Sequence: MPEATEHPPIGEAQTEPAQSGCPMVIKPPVEGGSNRDWWPNAVNLKMLQKDPEVIDPMDEGYDYREAVQTLDVDQLARDFDELCTNSQDWWPADFGHYGPLFIRMSWHAAGTYRVQDGRGGAGKGMQRFAPLNSWPDNVSLDKARRLLWPLKKKYGKKLSWSDLIVYAGNRAMENMGFKTAGFAFGRPDYWEPEEDVYWGAEHEWLGSQDRYAGANGDRTKLENPLGASHMGLIYVNPEGPEGNPDPIAAAIDIRETFGRMAMNDVETAALIVGGHTFGKTHGATDIVNGPEPEAAPLEQMGLGWSNPGVGIDTVSSGLEVTWTHTPTKWDNSFLEILYGNEWELFKSPAGANQWRPKDNGWANSVPMAQGTGKTHPAMLTTDLSMRMDPIYGEITRRWLDHPEELAEEYAKAWFKLLHRDMGPVQRYLGPLVPTQTWLWQDIVPAGKPLSDADVATLKGAIADSGLTVQQLVSTAWKAASSFRISDMRGGANGGRIRLQPQLGWESNEPDELAQVISKLEEIQGSSGIDVSFADLVVLGGNVGIETAAKAAGFDIEVPFSSGRGDATQEQTDVEAFSYLEPKADGFRNYVGKGLNLPAEYQLIDQANLLNLSAPQMTVLIGGLRALGITHGDSKLGVLTDTPGQLTNDYFVNLTDMGVKWAPAPADDGTYVGTDRDTGEVKYTASRVDLLFGSNSQLRALAEVYAEDDSRDKFVKDFVAAWVNVMDADRYDIGKGA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ATP6_STRPD
Sequence: MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKLKPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRF_PECCP
Sequence: MKNENLQQKHQTVSSPIVVALDYASQQAALSFVDRIDPQDCRLKVGKEMFTLFGPQFVQTLQQRGFDVFLDLKFHDIPNTVAHAVAAAADLGVWMVNVHASGGSRMMVAAKEALVPFGNDAPLLIAVTVLTSMDEDDLRGLGITVSPAEQAERLAVLTHNSGLDGVVCSAHEAQRLKQVCGQAFKLVTPGIRPAGSDVGDQRRIMTPVQAQQAGVDYMVIGRPITQSADPAQTLREIRVSLLNGASS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: MIEAP_HUMAN
Sequence: MAENLKRLVSNETLRTLQEKLDFWLKEYNTNTCDQNLNHCLELIEQVAKVQGQLFGILTAAAQEGGRNDGVETIKSRLLPWLEASFTAASLGKSVDSKVPSLQDTFDRERHKDPSPRDRDMQQLDSNLNSTRSQCNQVQDDLVETEKNLEESKNRSAISLLAAEEEINQLKKQLKSLQAQEDARHRNTDQRSSENRRSEPWSLEERKREQWNSLKQNADQQDTEAMSDYKKQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRRPSPNRSKLSNVARKAALLSRFSDSYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIHVRKSLTPSYVGSNDFENAVLDYVICHLDLYDSQSSVNDVIRAMNVNPKISFPPVVDFCLLSDFIQEICCIAFAMQALEPPLDIAYGADGEVFNDCKYRRSYDSDFTAPLVLYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSVSRCRSRSLSPICPRSQIGLNTMSRSRSPSPIRCGLPRF
What is the function of this protein?
Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage.  Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen.  Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade unhealthy mitochondria by accumulating lysosomes.  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.
What are the official names of this protein?
Mitochondria-eating protein, Spermatogenesis-associated protein 18.
What is the protein family that this protein belongs to?
Belongs to the MIEAP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane. Note=Localizes to the cytoplasm under normal conditions (PubMed:21264228). Relocalizes to mitochondrion outer membrane following cellular stress. Colocalizes with BNIP3 and BNIP3L at the mitochondrion outer membrane (PubMed:22292033).
Protein: ENTE_ECOLI
Sequence: MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASA
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms.  EntE proccesses via a two-step adenylation-ligation reaction (bi-uni-uni-bi ping-pong mechanism).  First, it catalyzes the activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via a reversible ATP-dependent pyrophosphate exchange reactions to yield the acyladenylate intermediate 2,3-dihydroxybenzoyl-AMP.  It can also transfer AMP to salicylate, 2,4-dihydroxybenzoate, gentisate and 2,3,4-trihydroxybenzoate.  In the second step, DHB is transferred from 2,3-dihydroxybenzoyl-AMP onto the phosphopantetheinylated EntB (holo-EntB) to form DHB-holo-EntB.  Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine.  It can also transfer adenylated salicylate to holo-EntB.
What are the official names of this protein?
Enterobactin synthase component E, 2,3-dihydroxybenzoate-AMP ligase, DHB-AMP ligase, 2,3-dihydroxybenzoate-AMP synthase, Dihydroxybenzoic acid-activating enzyme, Enterochelin synthase E.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. EntE subfamily.
What are the subcellular locations of this protein?
Membrane.
Protein: ACDG_METAC
Sequence: MKINSPLEAYKYLPQTNCGECGEATCMAFASKLIDRSGKTSDCPPLIKEKKFAKKLAELDRLLAPEIRQVTIGVGEKAVNIGGDDVLYRHKLTFFNKTKMFFDVADNMDEAALVERVNSIANFRKFYVGRNLLLDGVAIRAVSNDPAKFAAAVKKVAEAGLPMIFCSFNPAVLKAGLEAAKDLKPLLYAANKDNWKEVGELAIEYKVPVVVSAFNDLDALKTLAKTYAEAGIKDIVLDPGTYPTGKGLKDTFTNFLKIRRAGIMGDTEIAYPIMALPFTAWMAGIADPVSASYWETVMASVFTIRYGDIMILHSLEPYATLPEVHLAETIYTDPRTPVSVDGGMYKVGSPTADSPVLFTTNFALTYYTVESDISSNGIDCWLLAVDTDGIGVEAAVAGGQLTADKVKDAFDKAGFDLKTAVNHNTVVTPGLAARLQGDLEDKLGANVKVGPMDSGRIPGWMEKNWPPK
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit gamma, ACDS complex subunit gamma, 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase, ACDS complex methyltransferase, Corrinoid/iron-sulfur component large subunit.
Protein: CU02_CONVR
Sequence: LSSGATALSGVPRLTKPAGRLTTTTVAVAF
What are the official names of this protein?
Conopeptide Vi002.
Protein: SPEA_SALDC
Sequence: MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPMVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: SYT_SHEB2
Sequence: MPVITLPDGSKREFAHAVSTLDVAADIGPGLAKACIAGRVNGELKDACDLIETDAELSIITAKDEEGVEILRHSCAHLLGHAIKQMWPETKMAIGPVIDNGFYYDIDLEHKLTQDDIDALEKRMLQLAKTNYDVVKRVVSWQEARDTFAARGEDYKIAILDENISKDATPALYHHEEYTDMCRGPHVPNMRFCQHFKLMSIAGAYWRGNSENKMLQRIYGTAWADKKALSTHLTRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSIFLELERFIRRKLNQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCTDSQVQEEVSACIQMVYDTYATFGFENIVVKLSTRPEKRIGDDAMWDRAEEALKQALRDNNIEFTILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPSRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGRFPTWLAPMQVVVMNITDKQADYVEEVVKFFKEQGIRASFDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGIDLGKMRLEDFATKIHQQISLRSLKLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_NOCFA
Sequence: MSTLADVSSDITASAAWRKLHDHHGALAQRHLREIFAEDPERGRELTLQVADLHIDYSKHRATRETLQLLVELAREAGVEAHRDAMFAGEHINTSEDRAVGHVALRLPAGRTMTIDGADAGAQVHEVLRRMGEFTDALRSGQWRGATGERIETVVNIGIGGSDLGPVMVHQALRHYADAGITARFVSNVDPADLVAELTGLNPATTLFIVASKTFSTLETLTNATAARRWLVAALGEDAVAKHFVAVSTNAERVSAFGIDTANMFGFWDWVGGRYSVDSAIGLSVMATIGKERFAEFLAGMHAVDTHFATAPLEANAPVLLGLLGIWYANFFGAESRAVLPYSNDLARFPAYLQQLTMESNGKSVRADGTPVTTATGEIFWGEPGTNGQHAFYQLLHQGTRLIPADFIGFARPTDDLPTADGTGSMHDVLMSNLFAQTKVLAFGKTAEEIAAEGTAPNLVPHKVMPGNRPSTTILAPQLTPAVVGQLIALYEHQVFVEGVIWGIDSFDQWGVELGKQQALALAALLTAAEDPAPQDDSSTDALIRWYRAHR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_MESM1
Sequence: MCIILIMHHGKIIILSGPSGVGKGSIEKLLLEDEKLKLKFSTSVTSRKPRVNEIEGKDYFFRSEEEFSELIKEKKFIEWSRHLNNYYGTLKSEVDKILGAKFNVLIEIETTGALNILKYYKKKNMLNDVISIFILPPRLEELETRILNRGSETKEEIKIRIKKAKKEIKLKNKFKYNLTNNFLHECVEEVKNILKREIHEI
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
Protein: PA2AB_CALRH
Sequence: VEGSLVQFETLIMKLAKRSGFFWYSFYGCYCGWGGHGLPQDPTDRCCFVHDCCYGKVTNCNPKTATYSYTEENDGIVCGGDDPCKKQVCECDRVAAMCFRDNKDTYDSDKYWKLPPQKCQEDPEPC
What is the function of this protein?
Snake venom phospholipase that inhibits ADP-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 S1E6-b, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTFA_ECO55
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTGLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_SHEB8
Sequence: MFYKIAQKVMFQMDPERAHHLAIGSLKMTANSPLTCLYGQTIAPAPVSVMGLTFPNPVGLAAGMDKDGESIDAFHAMGFGHVEVGTVTPRPQPGNDLPRLFRLKPAKGIINRMGFNNKGVDNLVKNLIAKKTNIMVGVNIGKNKDTPVEQGKDDYLICMDKVYLHAAYIAVNISSPNTPGLRSLQYGDLLDELLSAIKTKQLELAEKHKKYVPIALKIAPDLTIEEIENIAQALIKNKFDGAIATNTTLTRDGVSGLANANESGGLSGKPLTELSTKVIKQLAICLKGQIPIIGVGGINSAEDALAKFDAGATMVQIYSGFIYQGPKLIKEIVNAYRLK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HCP_CLONN
Sequence: MSMFCYQCQETAGCKGCTSRGVCGKTSDVANLQDLLIYVVKGISIYDLKAEEAGIKNNEVNKFIMDALFSTITNANFSREDFIARIKDAIGLRDSIKDELVKNNVQIDDIKDDCALWKGISVEEFEAKAATVGILATENEDVRSLRELLTYGIKGMAAYAHHAYNLGYENEEIYTFMKKALVSTRNALSVDEMIGIVLECGKFGVDVMALLDKANTETYGNPEITKVNIGVRNNPAILISGHDLKDMEELLKQTEGTGVDVYTHSEMLAANYYPEFKKYDHFVGNYGNAWWKQNEEFKSFNGPILMTTNCLVPPKESYKDRVYTTGAVAFEGLKHIEDRKDGKAKDFSEIIEHAKRCASPMEIEKGEIVGGFAHNAVLSLADKIVDAVKTGAIRRFFVMAGCDGRAKSRNYYSDFAKALPKDTVILTAGCAKYKYNKLDLGDIGGIPRVLDAGQCNDSYSLAVIALKLKEVFELQDINELPISFNISWYEQKAVIVLLALLHLGVKNIHLGPTLPAFLSPNVAKVLVENFGIAGIGTVEDDIKLFLGEA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_RICPR
Sequence: MAKKNKNVLVRLVSTAGTGVFWVKKRNPRTQTEKLSFRKYDKVVRKHVLFKEEKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.