PharMolix/UniProtQA huggingface dataset:
Protein: LIPP_FELCA
Sequence: KEICFPRLGCFSDDAPWAGIAQRPL
What is the function of this protein?
Plays an important role in fat metabolism.  It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
What are the official names of this protein?
Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_DESPS
Sequence: MKKIAVLAGDGIGPEVMEQALKVLVAVQKKFGFELSFQHADVGGAAIDSHGVALPESTLTLCAESDAILFGSVGGPKWEHLPPAEQPERAALLPLRKHFDLFCNYRPARVFKSLTAACPLRADIIGDGFDILCVRELTSGIYFGTPKGREGAGEDEYAYDTMGYKRSEVRRIAHMAFAAARQRSGKVTSVDKANVLTTMVLWREVVLEVAKEYPDVKLNHIYVDNATMQLVRDPHQFDVMLCGNMFGDIISDEAAMLTGSMGLLASASLNTENFGLFEPAGGSAPDIAGQGIANPIAEILSAAMMLRYSLGYGEAADAIEAAVEKTLDRGICTADIAVDRSQAVNTAEMGDAIVAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLNB3_BRANA
Sequence: MRNEIQNETAQTDQTQGSMFSFFNLFPFLLPMFEVIKMVVASVASVVYLGFAGVTLSGSAVALAVSTPLFIIFSPILLPAIAATTVLAAGLGSKKVAAAPAASPSLSLLGIPESIKPSNVIPESIKPSNIIPESIKPSNIIPVSIKPSNIKDKIKDTIGKVKNKIKAKQEEKSKGKSEDSSKGKGKSKGEDTTTDEDKHGKGESKHGKGESKHGKGESTHGKGGKHGSEGSSMDEGKHGGKHGSGGSPMGGGKHGSGGKHESGGSPMGGGKHGSGGKHESGGASMGGGKHESVGKHGSGGKHESGGSPMGGGKHGSGGKHESGGASMGGGKHGSGGRHEGGGSAMGGGKHGSGGKHGSEGKHGGEGSSMGKNSLSKNKKEFHYRGQAMDASSTSESSDGSSSDGSSSDGSSSDGSSHGSGGKHI
What is the function of this protein?
Many of the major pollen coat proteins are derived from endoproteolytic cleavage of oleosin-like proteins.
What are the official names of this protein?
Oleosin-B3.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface (By similarity).
Protein: RS7_CERS4
Sequence: MSRRHAAEKREILPDAKFGDTVLTKFMNNLMIDGKKSVAESIVYNALDRVQTRLKREPLEAFHEALDNVKPSVEVRSRRVGGATYQVPVEVRTERREALAIRWLITAARKRNENTMEERLAAELADACNNRGTAVKKREDTHKMADANKAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GAUTE_ARATH
Sequence: MQLHISPSMRSITISSSNEFIDLMKIKVAARHISYRTLFHTILILAFLLPFVFILTAVVTLEGVNKCSSIDCLGRRIGPRLLGRVDDSERLARDFYKILNEVSTQEIPDGLKLPNSFSQLVSDMKNNHYDAKTFALVLRAMMEKFERDMRESKFAELMNKHFAASSIPKGIHCLSLRLTDEYSSNAHARRQLPSPEFLPVLSDNAYHHFILSTDNILAASVVVSSAVQSSSKPEKIVFHIITDKKTYAGMHSWFALNSVAPAIVEVKGVHQFDWLTRENVPVLEAVESHNGVRDYYHGNHVAGANLTETTPRTFASKLQSRSPKYISLLNHLRIYIPELFPNLDKVVFLDDDIVVQGDLTPLWDVDLGGKVNGAVETCRGEDEWVMSKRLRNYFNFSHPLIAKHLDPEECAWAYGMNIFDLQAWRKTNIRETYHSWLRENLKSNLTMWKLGTLPPALIAFKGHVHIIDSSWHMLGLGYQSKTNIENVKKAAVIHYNGQSKPWLEIGFEHLRPFWTKYVNYSNDFIKNCHILE
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls (By similarity).  Together with GAUT13, required for pollen tube growth, possibly through the regulation of pectin biosynthesis and repartition in the pollen tube wall (PubMed:23709340).
What are the official names of this protein?
Probable galacturonosyltransferase 14.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PURA_ALTMD
Sequence: MAKNVVVLGTQWGDEGKGKVVDLLTDRAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVTCIIGNGVVLSPDALMKEMTMLEERGVPVRERLKISEACPLILPYHIALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNAEDFAAKLKEVLDVHNFTLTQYYGEEAVDFEETLNGAMEVADILKAMVVDVTDELDKAHKAGLPIMFEGAQGTLLDIDHGTYPYVTSSNTTVGGVATGAGFGPLKLDYVLGIVKAYTTRVGSGPFPTELDCEVGQHLGVKGHEFGATTGRKRRTGWFDAVAMKRAVQINSITGFCLTKLDVLDGLESLQICVGYKDADGNVKDVPPMAADGYDKVTPVYEEMPGWTDNTFGVTEFEGLPQAAKNYIKRLEELTGVPVDIVSTGPDRNETIVLRSPYDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACD_STAAC
Sequence: MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: YAFD_SALCH
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPAGEPLSSEERIRILVWNIFKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNVHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRPRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVNEASVLVTRASDHNPLLVEFSPGKPEQ
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_ERYLH
Sequence: MSQALDYAKRLIAAPSVTPATGAVFDEMQAMLEPLGFAVHRFTRGEGEEGSDEAPVENLFAIRHGPEGSKHFAFAGHLDVVPPGEGWTSAPFEPEERGELLYGRGAVDMKGAIACMVDAVANVPQEAGTISFIITGDEEGPALHGTRALIDYMRSEGIKPDLCLVGEPTSVNRLGDMMKIGRRGSVNIWLEVEGTQGHVAYPHLAGNPLPAMVEILRELNNLPLDEGTDWFQPSNLEITEIDVPNRAHNVIPAKAKARISIRFNDTHSGASLSKQVIEIAEKHGGTARPVISGEPFLTEPGAFSSMIAAAVKAETAIDPEPSTTGGTSDARFLRSVCPVIEFGLCNATMHKRDEAVAMADLDTLSRIYARVAQAALSS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RAN1B_LOTJA
Sequence: NFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTARLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPFLYLARKLAGDPNLHFVESPALAPPEVQIDLAAQQQHEAELAAAASQPLPDDDDDAFD
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran1B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRCA_BPT4
Sequence: MKAYQILEGTHKGTIYFEDGIQARIIVSKTFKEDSFVDPEIFYGLHAREIEIEPQPTVKIEGGQHLNVNVLRHETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: PDXJ_RHORT
Sequence: MSRVLRLGVNIDHVATIRNARGGDHPDPLRAAKIAAEAGADGITAHLREDRRHIGDRDIARLRDEIDLPLNLEMAATAEMLAIALRHRPHAACIVPEKREERTTEGGLDVVGGAVHLAPIITALGEAGVRVSLFIEPDLRQLDAARALGAPVVELHTGAYCDAAAGPAREAQFLRIDKAARHAQALGLECHAGHGLTYDTVEPVAALPAIAELNIGHFLIGEAIFVGLHQAIARMRAHMDAALRGGVAA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_STAAB
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMRKKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_MYCS2
Sequence: MAQAKKGGTAAKKGQKTRRREKKNVPHGAAHIKSTFNNTIVSITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVKKVDVFVKGPGSGRETAIRSLQAAGLEVGTISDVTPQPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RIBA_BLOFL
Sequence: MQLKRVAEAKLPTFWGDFLIIGFKENQTEHNHIALTYGDLTGSNPVLTRIHSECLTGDALFSSRCDCGIQLSTALRYITEEGQGILIYHRQEGRNIGLLNKIRAYSLQDHGADTVEANQCLGFNADERDFTVCADILKLLNIQTIRLLTNNPQKIEILNKSHIIVTERVPLIVGRNPKNSKYLDTKALKLGHLFSSYYK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RL22_SALAI
Sequence: MPGKGDAPVLPGARAVARYVRISPMKARRVVNLVRGLPAKEALTVLQFAPQAASEQVYKVLASAIANAENNERLDPDALLVSEAYVDEGPTMKRFQPRAQGRAYRIRKRTCHITVVVEAVAPAAPTKAASKKAAPAKQTTPAATESKTEGAE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CSN8_ARATH
Sequence: MDLSPVKEALAAKSFDKIADICDTLMLQVASEGIEYHDDWPYAIHLLGYFYVDDCDSARFLWKRIPTAIKERKPEVVAAWGIGQKLWTHDYAGVYEAIRGYDWSQEAKDMVAAFSDLYTKRMFQLLLSAYSTITIHDLALFLGMTEDDATTYVVENGWTVDAASQMASVKKQAVKREQKVDSSKLQRLTEYVFHLEH
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes.  The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.
What are the official names of this protein?
COP9 signalosome complex subunit 8, CSN complex subunit 8, Constitutive photomorphogenesis protein 9, Protein FUSCA 7.
What is the protein family that this protein belongs to?
Belongs to the CSN8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS4_COREF
Sequence: MTFTILPAVDVVNGQAVRLDQGEAGTEKSYGTPLESALRWQEQGAEWLHFVDLDAAFNRGSNHELMAEITRQLDIKVELTGGIRDDASLERALATGATRVNIGTAALEKPEWIADVIRRHGEKIAVDIAVRLENGEWRTKGNGWVSDGGDLWEVLERLDSQGCSRFVVTDVSKDGTLTGPNVDLLRDVAAATDAPIVASGGISTLEDVLGLAKYQDEGIDSVIIGKALYEHRFTLAEALEAVEKLG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_STAA2
Sequence: MVHNKNNTILKMIKGEETSHTPVWFMRQAGRSQPEYRKLKEKYSLFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPIKTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMYRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYRRYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQLGVTKTLQGNLDPSILLAPWNVIEERLKPILDQGMENGKHIFNLGHGVFPEVQPETLRKVSEFVHTYTQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT5A_RAT
Sequence: MKKPIGILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSWWSLGMNNPVQMSEVHIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Can activate or inhibit canonical Wnt signaling, depending on receptor context.  In the presence of FZD4, activates beta-catenin signaling.  In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression (By similarity).  Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation.  Stimulates cell migration.  Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor.  Mediates motility of melanoma cells (By similarity).  Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle.  Inhibits type II collagen expression in chondrocytes (By similarity).
What are the official names of this protein?
Protein Wnt-5a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: TTC21_CAEBR
Sequence: MDPDIENERIEDRKKWGHKDVEHWRAVSNVHYYTREGFYGTAILVCDGRLATVQDVPLAILKGVCLVLLGKIPEAIRHLEAFSNDQNFSLGALYALKWAHASAFNPDSKSIVEIEAEISKTARNEKTPYTSYASAAEVLYFAGEFQKAKQNLDIAGKRSTEKHAKYYCLMGWIDLGLGKKQKSTQELFEKAGGQEYPDGNIGRCKILEGHHSASEMRVAANELAISTIHFLPGHIEKAKALIMLRDWHGVMDCIVNADQQEGSNPYIEILRTTHGICFAGEVSQLNRTLQLLLKSLDDNESINHALYAKITKLIVSISGKNEKILRHARDFLIRALKLSRKPDYVALSLRIAFGLGDAREVSVLSQELIALDCEDPYAILSSVTSMLMVSRVSDARAQFDIMPAAHPKLLESPFYYLIASVLAKHSKDKSFENFRQHIENLIEMLRNQLQSFPFGIDYLLLFSSDLLYFAIEQCFDFYPLVPMKAPDDTMKLTSKMLQMIYDVAPGLAYCALQLARNCYLVSNTNAAEKWIYKALEKDDSLADAHILRAQLILDRGGKIQDADDALVTGLNFNFKLRETSLYHLIKSKTFKKRNENDEALKTLKMALQIPKKEMSNNLFVPKESADTHKISVQLELIDTLRQTKRIQDAEDTMADAMAEWAGQPEQHQLVIAQAQLYLTKGHTEKALAILRKIQPGQSNFHLSRIRMAEIYLEEKKDKRMFAACYRELLKVEPTPGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLKLANLLLRLKNYEKCEKILRAPLDREPEPSDTETIQTHIQFLLLLAECHEMVENIPEAMKDFEKAKSLHNKIQDKTNTTGLRKEGARICNLQAELYYRRHEFPPAIEVCKQALQFYETDLKSNLLLSRIYKDENKWTLVLQPCQAVLQVDPHNDEANLILADFYYIKSEADHAMTSYITLLNKNPLHWHALFRVVELYCRKGEHHKADEFLNSARDANPRCVTEAGYSVCRGRFEWYTGDQSQALRCYSRAKDSPNVVWREKALYAIIDICLNPENEKILDADSVENAEQKTTEEAADQQSTAQVYLDLLGKVGPTERYRLAQNFVRMHTTDKNTIMATIDEFNKMAYAADKSIISVAAIYGIAKGYWLLKKQQPAKQLLKSLHGRVWNFDDAEYLEKCWLLMAEIYVGASKWEQAGTYLDQVLKYNCNSLRAFELYGQAKEKEQKYVEASKIYEKAFNTTNQKSCSFGYKLAFTLLKTRRLFLCIETCQKVLDINPQYPKIQREIMDKARGMIRTT
What are the official names of this protein?
Tetratricopeptide repeat protein 21 homolog, TPR repeat protein 21 homolog.
What is the protein family that this protein belongs to?
Belongs to the TTC21 family.
Protein: MGLA_VIBCH
Sequence: MVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGKSTLLKCLFGIYEKDEGDIIFLGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLGRYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSVSQMQMLEIAKAFSYDAKVVIMDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRPLKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEILGVAGLVGSRRTDIVETIFGVRERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGIYSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDSMRVKTPSHQTHIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGITDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CP131_DROME
Sequence: MDLCLKGSQINLATRQKTKPKYTSRSLTTLHNPCPHFRPRSANFLQQRSRSSPFLGRPQSADPKFGRRLSNYFVEKELRNGGKRQVSSNDLLKSLLEEPIKRSWLCRSTCNSSESDYSLHKRTPDSSEEGEQFLVNMPVGEKVKSYSSYSGNQGLSNGALLQRTAKPDLPGRVSFSKPNMHADLDSSDCDNDKQEVRPSISAPGPLTLPSFLSKVEQADPVGQKKSVHFGSTAAEGEVLAETYEYPKCPSENCTCSTRSSSTTSTNEASASDVKCACDAPSCRFMESSKQVEPTSPTPTLPKAPSSELDVIREYKQAVEGVQVVKNHLGTDTLNNIEILPNYLDKYASPTKEKQNNLSETKNMATNSSAVNNGSVVYRPVGNPRNFGAENNFLPAVQDDRRSFANGSSDGVINNYLKVASTPPFVGKKKENVKPASADPIARSSKSKVTKSTINPAPLGKMKKAISVGSLREERKLSEYNLDKVDSWMSMQDQKQYDGKHKPGLEDLDEAQDNDTASQLSLKSNEDSRDSTYDEIVSVIKEIEEDKKRDNFSEGIPSELNLNLDSRCETADTVTVSEGKVPESGDKYKDILAYLNNVESSCDKTLMETRRSIPDSNRSEVEFVVEPDVTDEVPKLSELLMLPNHQLARRVIALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRKDYCVK
What is the function of this protein?
Cilium-specific protein with a role in cilium/flagellum formation (PubMed:21750193, PubMed:27646273).  May be involved in transport of components into the growing cilium (PubMed:21750193).  In germ cells and sensory neurons, plays a role with Cby in the building of the transition zone necessary for the formation of the ciliary cap and for the correct elongation of the axoneme (PubMed:27646273).
What are the official names of this protein?
Centrosomal protein of 131 kDa, 5-azacytidine-induced protein 1, Dilatory protein.
What is the protein family that this protein belongs to?
Belongs to the CEP131 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Co-localizes with the pericentriolar material (PCM) protein cp190 at centrosomes in undifferentiated sensory neurons (PubMed:21750193, PubMed:27646273). Localizes to the ciliary base, including the basal body and transition zone in sensory neurons and germ cells (PubMed:21750193, PubMed:27646273).
Protein: UBIA_SHESR
Sequence: MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTRSRPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTGEVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGQYDRQIIGLFQFAALLCFIAAGWSADRGLLYGLGLLTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLAW_AZOCH
Sequence: XXIGIFYGSSSGVTGKV
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin A, FldA.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: LEUD_BACHK
Sequence: MEPFRIHKGTAAVLMNDNIDTDQIIPKQYLKRIERTGFGKFLFDEWRYDNNRQENPNFPLNAPDRKGASILITGDNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKEMREKLVKTDAREQIEVDLENEVITTSTHRFHFTIEKMWKEKLLNGLDEISITMQYEQEIKEYERRVAVY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.