PharMolix/UniProtQA huggingface dataset:
Protein: PTLA_BORPE
Sequence: MNPLKDLRASLPRLAFMAACTLLSATLPDLAQAGGGLQRVNHFMASIVVVLRGASVATVTIAIIWAGYKLLFRHADVLDVVRVVLAGLLIGASAEIARYLLT
What is the function of this protein?
Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane.
What are the official names of this protein?
Type IV secretion system protein PtlA, Pertussis toxin liberation protein A.
What is the protein family that this protein belongs to?
Belongs to the PtlA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WSC4_YEAST
Sequence: MQTSMVSAKVSIWLVCSVICSSLVRATQSVCSSQNTATTDGVRNQFQSNGWCSNNCAGHQFAIVQGFMCWCSDSEPSTQTSVGDCSGTCPGYGYEDCGNADKDLFGYIYLGQTPLSSVQSVETSTESSVYVSSSSITSSSSTSIVDTTTISPTLTSTSTTPLTTASTSTTPSTDITSALPTTTSTKLSTSIPTSTTSSTSTTTSTSSSTSTTVSVTSSTSTTTSTTSSTLISTSTSSSSSSTPTTTSSAPISTSTTSSTSTSTSTTSPTSSSAPTSSSNTTPTSTTFTTTSPSTAPSSTTVTYTSTTASPITSTITSVNLQTSLKYSVITVTSVHTMDTNISEITSRYLTMKKVITQIYSSTLGATPTSAVATTSASVGGRITNNNNSNTTNSNTPTNKSTEKKGYWDSPGKIAATFVVVGVVCLVIICILIYLIHHYRTRPARKAQDFENEYQSKFYQSKYPNEVTTTTLHTPSPSSNSTFSTPRLIYTDEKGQIMSESPSPRQSTYSLTAGSPPNDPSTLASPFHDPILPRRTSTFLHSPIQKQHEKMESNVTLGEDTVLVDQRLDPSKMLNTLANDDATNHSTISLSDNVDYSRRVLRLMNE
What are the official names of this protein?
Cell wall integrity and stress response component 4.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL15_SPHAL
Sequence: MTIKLNELRDNNGARKGRMRVGRGIGSGKGKTAGRGQKGQKARSGVAINGFEGGQMPLHMRIPKRGFNNIFGKDFAIVNLGMVQKLIDAKKLDAKATIDHAALKAAGVARGGKDGVRLLAKGELTAKVTFAVAGASKGAIEAVEKAGGKVELPEARPEGDGKKATRKAEAAAKNA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PSBL_CUSRE
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Single- pass membrane protein.
Protein: YSH1_KLULA
Sequence: MTQLENEVPDKDHLRFFSLGGSNEVGRSCHILQYKGKTLMLDAGIHPAHQGLASLPYYDEFDLSTIDLLLISHFHLDHAASLPYVMQRTNFRGRVFMTHPTKAIYRWLLNDFVKVTSIGDSPGQDSSNDNLYSDEDLAESFDRIETIDYHSTMEVNGIKFTAFHAGHVLGAAMFQIEIAGVRVLFTGDYSREVDRHLNSAEVPPQSSDVIIVESTFGTATHEPRQNRERKLTQLIHTVVSKGGRVLLPVFALGRAQEIMLILDEYWQNHKEELGNGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFKDSQTNPFIFKNISYLKNLDEFEDFGPSVMLASPGMLQNGLSRDILEKWCPEEKNLVLVTGYSVEGTMAKYLLLEPEAIPSVHNPEITIPRRCQVDEITFAAHVDFRENLEFIELIGASNIILVHGESNPMGRLKSALLSNFSSLKDTENEVHVFNPRNCVFVDIEFKDVKVARAVGKIIEDLDEFITEEDALKNEKRITEIHEEDPETEESKTEIVKEENEKIVSGILVSDEKNFDLSLVSLSDLREHYQQLSTTVLTERQTVHLDCKSELVYWHICQMFGDVDVYIDEENVSLKNINPEFKTRKIKKGELEIKIMGDVILNIVDNVATLQWTQNVISDSVADSVMAILLSVESAPASIKMSSKSCGHHHGHDDHTTKIKNISRVFKEQFGDTFTLFLNEEDSKEEIKGTINLGKTTACINFSKMVVEECNSNPLKGRIESLLKIGSDLVAPLC
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
Endoribonuclease YSH1, mRNA 3'-end-processing protein YSH1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DLTA_BACCZ
Sequence: MKLLEQIEKWAIETPDQTAFVWRDAKITYKQLKEDSDALAHWISSEYPDDRSPIMVYGHMQPEMIINFLGCVKAGHAYIPVDLSIPADRVQRIAENSGAKLLLSAATVTVTDLPVRIVSEDNLKDIFFTHKGNTPNPEHAVKGDENFYIIYTSGSTGNPKGVQITYNCLVSFTQWAVEDFNLQTGQVFLNQAPFSFDLSVMDIYPSLVTGGTLWAIDKDMIARPKDLFASLEQSDIQVWTSTPSFAEMCLMEASFSESMLPNMKTFLFCGEVLPNEVARKLIERFPKATIMNTYGPTEATVAVTGIHVTEEVLDQYKSLPVGYCKSDCRLLIMKEDGTIAPDGEKGEIVIVGPSVSVGYLGSPELTEKAFTMIDGERAYKTGDAGYVENGLLFYNGRLDFQIKLHGYRMELEEIEHHLRACSYVEGAVIVPIKKGEKYDYLLAVVVPGEHSFEKEFKLTSAIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLSEVTA
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CAUSK
Sequence: MAKPASIKIRLNSTADTGFFYVTKKNARTKTEKMVLKKYDPVIRKHVEFKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: P4HA3_HUMAN
Sequence: MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-3, 4-PH alpha-3, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PPK1_TYRGL
Sequence: DGYTPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-1, PK-1, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBEY_ANADE
Sequence: MIVRLTSEHPDGARAARRLRARAAAFLAALGREDAELSILLVTDRRIRTLNREWRQKDQATDVLSFPISEPPGAGALLGDVVISLDTAARRARSDGRRVGAELDRYLAHGILHLLGYDHERPADARAMAEKEAELARAEGLVGAALREGRREGRAGEAKDRWTRSPTSISTPSRSGSTARGSRAKTSRAGSRT
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_CAUVC
Sequence: MADLDAAWTRLEAAAKAAGDKRIVEFFDAEPGRLDALTLDVAGLHLDLSKQAWDEAGLEAALDLAHAADVEGARARMFDGEAINSSEGRAVLHTALRAPAGADVKALGQPVMAEVDAVRQRMKAFAQAVRSGAIKGATGKPFKAILHIGIGGSDLGPRLLWDALRPVKPSIDLRFVANVDGAEFALTTADMDPEETLVMVVSKTFTTQETMANAGAARAWLVAALGEQGANQHLAAISTALDKTAAFGVPDDRVFGFWDWVGGRYSLWSSVSLSVAVAAGWDAFQGFLDGGAAMDEHFRTAPLEQNAPVLVALAQIFNRNGLDRRARSVVPYSHRLRRLAAFLQQLEMESNGKSVGPDGQPAKRGTATVVFGDEGTNVQHAYFQCMHQGTDITPMELIGVAKSDEGPAGMHEKLLSNLLAQAEAFMVGRTTDDVVAELTAKGVSDAEIATLAPQRTFAGNRPSTLVLLDRLTPQTFGALIALYEHKTFVEGVIWGINSFDQWGVELGKVMANRILPELESGASGQHDPSTAGLIQRLKR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYR2_NOSS1
Sequence: MSSSVAERLAIRDAIGNKVELRQNWSEDDLQKVFRAAYEQIFGRQGIYASQKFTSAEALLRNGKISVRQFVEILAKSEFYKECFFYKNSQVRLIELNYKHLLGRAPYDQSEIADHVDIYAARGYDADIDAYIYSSEYENAFGNSIVPYYRGFQSIPGMKTVGFNRICELYRGRGNSDNAQMGRTNSRLRTKVSLNLPNGILPPTSAGTNFVSAAPTLISSATKGDNRMFVIEAIAGGLNTNVAVRRSRQVYTVSYERLSATYQEIHKRGGKIVKISQV
What is the function of this protein?
Rod linker protein, associated with phycoerythrocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 34.5 kDa linker polypeptide, phycoerythrocyanin-associated, rod.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of a phycobilisome rod associated with phycoerythrocyanin.
Protein: YICR_ECO45
Sequence: MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: RL36_BUCAT
Sequence: MKVQASVKVLCRSCKIIKRNNVVRVICSNDPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HOMEZ_MOUSE
Sequence: MLGHRLLPSLDFPAVSEGYKPEHDMSPNKDASSLNSSAAGLVCLPPVSEELQLVWTQAIQTSELDGNEHLLQAFSYFPYPSLADIALLCLRHGLQMEKVKTWFMAQRLRCGISWSSEEIEETRARVVYHRDQLLFKSLLSFTQQSVRPPQERPPVLRPEQVALGLSPLAPSEQPTHMKGLKVEPEEPSQVSQLPLNHQNAKEPLMMGSRTFSHQSDCQDLQISGLSKEQAGRGPDQSCGKTASWNHFTAVHQPDKPASVSLLDNSCKEESEPSGIPPSSSTSSPSFQALANGTTATPKPLQPLGCISQSLSPSKKALSPQVEPLWPQRLWNNSEPNSAGPTEYLSPDMQHQRKTKRKTKEQLAILKSFFLQCQWARREDYHKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDNAVLGTPSFQDPAIPTPSTRSLKEWAKTPPLPAPPPPPDIRPLEKYWAAHQQLQEADILKLSQASRLSTQQVLDWFDSRLPKPAEVVVCLDEEDEEDEEDELPEDGEEEEEEEEDDDDGDDDVIIWD
What is the function of this protein?
May function as a transcriptional regulator.
What are the official names of this protein?
Homeobox and leucine zipper protein Homez, Homeodomain leucine zipper-containing factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANC_FLAPJ
Sequence: MIIFEKQTDVKTYLKPFLQDQKTIGFVPTMGALHQGHLSLMKESLQNNDHTVVSIFVNPTQFNNPEDLKKYPRTLESDVEKIKLLNHKIIIYAPTVEDIYEGKTASKSFDYDGLELQMEGKHRPGHFDGVGTIVKKLFEIVNPTHAYFGEKDFQQLAIVRKLVQKNKINTKIVGCKILREANQLAMSSRNERLTADERTKAAMIYNTLAEAKKLFGTKSANEVTKWVTKTFENQSMFELEYFEITDEQTLLTCKRKNKNKKYRAFIAVFVNNIKLIDNISLK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_LEPBJ
Sequence: MIRHKLQNFVNSLPISPERSCSYYPDRLSQIQYLPLQGKIEKDNLQFFFDSGFRRTGNILYRTSCNACRECLSYRVPLNQFVPSRNRKRLLKKNSDLVVRFGSPHLTVEKEILYLRYQRSRYQSFVIGESDQELLEGMRWNLFGYPENSLEMTLSLDEKILGFMILDSASDSLSAVYSVYDPDYPDRSLGSFAILYSILYAKELGMKYYHLGYFLPGHPDMDYKKHWVPSEIRELDTNDWIPFEEFQKKYADFSW
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIT_CAEEL
Sequence: MLLGKFLLVASFILPIAYTWTGATIRNHPADVVAARNKITSRSVARSEPTNSYIRPCYFTNWAQYRQGRAKFVPEDYTPGLCTHILFAFGWMNADYTVRAYDPADLPNDWAGEGMYRRVNKLKVTDTQLKTLLSFGGWSFGTALFQGMAASSASRKVFIDSAITFVRTWGFDGIDIDWEYPSGATDMANYVALVKELKAACESEAGSTGKDRLLVTAAVAAGPATIDAGYDIPNLAPNFDFILLMSYDFFGAWASLVGFNSPLYATTELPAEWNGWNVDSSARYWNQKGMPKEKIIVGMPTYGRGWTLNNASAINPGTSGSPAKITQYVQEAGVGAYFEFCEMLANGATRYWDSQSQVPYLVQGNQWWSYDDEESFANKMAYVKREGYGGAFVWTLDFDDFNAGCSNSNGQLYPLISVIAKELGGVIIPKKGGVTTAPTTVATTVTTGRPPMTSAVTTTTAATTTTTRAATTTTASNTNVCSGKSDGFYPNSNNCGLFVLCLSSKSYSMSCPSGLQYSASLKYCTTSTASGCSVTTTRAPTTTTKSAPTVTTTTRAPTTTTPAFKCTKDGFFGVPSDCLKFIRCVNGISYNFECPNGLSFHADTMMCDRPDPSKCAK
What are the official names of this protein?
Probable endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
Protein: PANCY_SYNPW
Sequence: MGGLHQGHARLIATAVTSCGGKGSVLVSTFVNPLQFGVDEDFDCYPRTFEDDCALAEQAGASALWCPDERQVYPYGTSEGWRLQAPARLTAHLCGPWRSGHFDGVVTVVMRLLGLVRPHQLWLGEKDWQQLTILRHLVNDFGLRVRVRGCPTVREGDGLAASSRNRYLGDAQRTVASAFSSALCATARDVCAGSVDEASAQVALRQQLREAGLEVEYVETVDPVTLQPARPGRSIRLLAAAVRCGETRLIDHVFIMTRSPIVAIDGPAGAGKSTVTRAFAERMGLLYLDTGAMYRAVTWWVQSNGADPSSAPAVEALLEGLEVDLSPLKDGVQTVRVNGRDITDAIRDPEVTGSVSLVAAHPCVRALLTKQQQRLGERGGLVAEGRDIGTAVFPDADVKVFLTATPEERARRRAKDLEARGHAVPDLAALEAQIVERDRLDSTREVAPLVQADDATELITDGMSIEAVIDALEDLFRFRVAKEIWPTPQG
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1294_PYRFU
Sequence: MILLLTGMPGSGKGVVAREFEKRGIPVVSMGDAIREEAEKRGIPKTPEGLKEVSLKVREELGPGAVAILTVPKVRKLLELNPVVVVEGVRSPYEVEEFRKEFKNEEIKVVAIHSSPKSRFQRLLKRQRSDDPKTWEEFVERDRKELNFGIGEVIALADYIIVNECGFDQLKANIEKLISMIFDGKI
What are the official names of this protein?
UPF0200 protein PF1294.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: AMPA_PROMM
Sequence: MEICLFPATLQSWTGDVLMVGMFEGKMEERLNELETLCKGSLMQSLEKQMFKGKSGEIATVQLLQNKPNLLVLVGLGEPQEMRLDDLRKAAALGAKASLGCSGTLGMMLPWEPLDAASAARAVAEAVRLSLYKDLRFRSAPEPRSTPTKLELIGLPDSAGKDLQAVHPTCAGVELARQLVAAPANSLTPAALAQTAIQLAHEHGLECSVLERSDCAEREMGAYLAVSQGSDLEPKFIHLTYRPQGPVQRRLALVGKGLTFDSGGYNLKVGAAQIDLMKFDMGGSAAVLGAARAIAELRPKGVEVHVIVAACENMVNGSAVHPGDLVRASNGTTIEINNTDAEGRLTLADALVYTCGLEPDAIVDLATLTGACVIALGEEIAGLWTGHDPLAEGLTAAAEAAGEGLWRMPLPSSYREGLKSNLADLKNTGPRPGGSITAALFLKEFVEASIPWAHIDIAGTVWSEKGRGLNPSGATGYGVRTLVNWICSQS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD2_PEPAC
Sequence: MKGSKEIKLTQMVTASGUAAKIGPEDLAKALVGLPKMFDERLLVGFDTSDDAAVYRLDDDKALIQTLDFFTPMVDDPYLFGQIAASNSLSDVYAMVGKPIVAMNIVCFPSCHDMSILGEILKGGADKVIESGAILVGGHTVDDKEPKYGLSVAGLVHPDKVLANSGARPGDALILTKPIGTGIVSTGMKAAMVQKSTEDEVVKIMAHLNKYAAEALDGFNVNSVTDITGFGFLGHAAEMAKGSGVTLEISSKDIPIMSEAEELAKMGIIPAGMYRNKKFIQSDVLCEGVSEHIMDILYDPQTSGGLLVSVPQEHARALADKMTSCGSLAAKIVGRVLSKEEKSIIVI
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase 2, Selenium donor protein 2, Selenophosphate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: PXG_PINEL
Sequence: MASNESLQTTAAMAPVTIERRVNPNLDDELPKPFLPRALVAVDTEHPSGTPGHQHGDMSVLQQHVAFFDRNNDGIVYPWETFLGLRAVGFNIIISFFGCLIINISLSYATLPGWIPSPFFPIYIDRIHRAKHGSDSEVYDTEGRFVPSKFEEIFTKNARTHPDKLSFSELWNLTEHNRNALDPLGWVAAKLEWFLLYLLAKDPHGFVPKEAARGVFDGSLFEFCEKSRRSNKQQ
What is the function of this protein?
Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies.
What are the official names of this protein?
Peroxygenase, Caleosin.
What is the protein family that this protein belongs to?
Belongs to the caleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Microsome membrane.
Protein: TP1A_RANCS
Sequence: FLPIVGKLLSGLL
What is the function of this protein?
Antibacterial peptide.  Has activity against the Gram-positive bacterium S. aureus (MIC=8 uM) and the Gram-negative bacterium E. coli (MIC=128 uM).  Has a moderate hemolytic activity (LC(50)=75 uM).
What are the official names of this protein?
Temporin-1CSa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
Protein: MSRA_DICDI
Sequence: MTKATFAAGCFWSVELLFQRVAGVTKTRVGYTNGTVENPTYRQVCSGKTGCAEAVELEYDPEKVTYNQLLGLFWSKHDPTTLNRQGNDVGTQYRSGIYYHNEEQKNEAIASKEKEQLKYKDPISTEILPAGVFYPAETEHQQYLGNY
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: Y432_STRS2
Sequence: MKLPKEGDFITIQSYKHDGEIHRTWRDTMVLKTTENAIIGVNNHTLVTENDGRRWVTREPAIVYFHKKYWFNIIAMIRENGVSYYCNLASPYVLDNEALKYIDYDLDVKVFADGEKRLLDVDEYERHRKAMKYSDDIDFILKENVKILVDWINNQRGPFSPAYVNIWYKRYLELRSR
What are the official names of this protein?
UPF0374 protein SSU98_0432.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RND_DESPS
Sequence: MKQENIISTTEDLKKIVNKALKLDAVGLDTEFVWERTYYPQLGLIQIALSDEECYAIDPLSIKDLSPLGELLADRNTIKILHDAPQDLIIMSQATGATPQNIFDTRLAAGFAGSISTISLLQLVSEQLETELDKSETRTNWLKRPLTEKQLSYSLNDVRYLRATRVILLSKIIGPKIKSWLQEELNLLNNPANYSTIADESRYKKVKGVNKLDRKSIGVAQEIATWREQKARELNRPRGHVIKDDILLEIAAIRPTRPEELANTAISTKAAERYGNDICQATARALNKKEVDLPHQQKRSQLSSQEKGALAQLKELITLKCDILGIDPALLGNSNELKKIIQTLYKGKTTHMRQSFGWRKEFLKDFYQIHRDTI
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_BPV2
Sequence: MALWQQGQKLYLPPTPVSKVLCSETYVQRKSIFYHAETERLLTVGHPYYQVTVGDKTVPKVSANQFRVFKIQLPDPNQFALPDRTVHNPSKERLVWAVIGVQVSRGQPLGGTVTGHPTFNALLDAENVNRKVTAQTTDDRKQTGLDAKQQQILLLGCTPAEGEYWTTARPCVTDRLENGACPPLELKNKHIEDGDMMEIGFGAADFKTLNASKSDLPLDIQNEICLYPDYLKMAEDAAGNSMFFFARKEQVYVRHIWTRGGSEKEAPSKDFYLKNGRGEETLKIPSVHFGSPSGSLVSTDNQIFNRPYWLFRAQGMNNGIAWNNLLFLTVGDNTRGTNLSISVAADGNALSEYDTGKFNLYHRHMEEYKLAFILELCSVEITAQTLSHLQGLMPSVLQNWEIGVQPPASSILEDTYRYIESPATKCASNVIPPKEDPYAGLKFWSIDLKEKLSLDLDQFPLGRRFLAQQGAGCSTVRKRAVATRNSSKPAKRKKIKA
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: CRDR_HELPY
Sequence: MQKKIFLLEDDYLLSESVKEFLEHLGYEVFCAFNGKEAYERLSVERFNLLLLDVQVPEMNSLELFKRIKNDFLISTPVIFITALQDNATLKNAFNLGASDYLKKPFDLDELEARIKRFFNDDPIEIMPNIFYHQNCLSVRGKKEILPPKTAQLLEYFLEHKGQIISSQALENNLWEQAIDDSTLRTYIKVLRKLLGKNCIETHKGVGYRFNPL
What is the function of this protein?
Member of the two-component regulatory system CrdR/CrdS that induces the transcriptional induction of the copper resistance determinant CrdA (PubMed:12933888).  Upon phosphorylation by CrdS, functions as a transcriptional regulator by direct binding to promoter regions of target genes including the crdA promoter or nitric oxide-responsive gene promoters (PubMed:26082024).
What are the official names of this protein?
Transcriptional regulatory protein CrdR.
Protein: VE2_HPV42
Sequence: MERLAKRLDACQEQLLELYEENSRDLQKHIEHWKCLRMEAVVLYKAREMGFANIGHQIVPTLETCRAKAHMAIEIHLALETLLQSSYGKEPWTLQETSNELWLTNPKKCFKKQGRTVEVIFDGKQDNAMHYTAWTYIYIQTVQGTWCKVQGHVCHAGLYYIVENMKQFYCNFKEEAKKYGVTDQWEVHDGNQVIVSPAPISSTTSTDAEIPSTGSTKLVQQVCTTNPLHTTTSIDNHHADCTDGTAYNVPIQTSPPRKRYRQCGQSPSQHLQHSNPSIPSIPSASVDPGLCGVRTNSENCNKRRNHCGSQATPVIHLQGDPNCLKCLRFRLKRNCSHLFTQVSSTWHLTENDCTRDTKTGIITIHYYDEAQRNLFLNTVKIPSGIKSCIGYMSMLQFI
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MDH_GEOSW
Sequence: MTMKRKKISVIGAGFTGATTAFILAQKELGDVVLVDIPQLENPTKGKALDMLESSPVLGFDANIIGTSDYADTADSDIVVITAGIARKPGMSRDDLVTTNQKIMKQVTKEVVKYSPNCYIIVLTNPVDAMTYTVFKESGFPKNRVIGQSGVLDTARFRTFVAQELNISVKDVTGFVLGGHGDDMVPLVRYSYAGGIPLEKLIPKDRLDAIVERTRKGGGEIVNLLGNGSAYYAPAASLAEMVEAIIKDQRRILPAIAYLEGEYGYEGIYLGVPTILGGNGIEKVIELELTEEEKAALAKSVESVKNVMRVLE
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.