PharMolix/UniProtQA huggingface dataset:
Protein: FGF2_PANTR
Sequence: MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTKERPSGSRLGDHGRGRALPGGRVGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: 5NT3B_HUMAN
Sequence: MAEEVSTLMKATVLMRQPGRVQEIVGALRKGGGDRLQVISDFDMTLSRFAYNGKRCPSSYNILDNSKIISEECRKELTALLHHYYPIEIDPHRTVKEKLPHMVEWWTKAHNLLCQQKIQKFQIAQVVRESNAMLREGYKTFFNTLYHNNIPLFIFSAGIGDILEEIIRQMKVFHPNIHIVSNYMDFNEDGFLQGFKGQLIHTYNKNSSACENSGYFQQLEGKTNVILLGDSIGDLTMADGVPGVQNILKIGFLNDKVEERRERYMDSYDIVLEKDETLDVVNGLLQHILCQGVQLEMQGP
What is the function of this protein?
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).  The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233).  Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).  UMP and purine nucleotides are poor substrates (PubMed:23223233).
What are the official names of this protein?
7-methylguanosine phosphate-specific 5'-nucleotidase, 7-methylguanosine nucleotidase, Cytosolic 5'-nucleotidase 3B, Cytosolic 5'-nucleotidase III-like protein, cN-III-like protein, N(7)-methylguanylate 5'-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the pyrimidine 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_BURM1
Sequence: MSASDLTSVQAAAPQGRRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYIGADDTHGTPVMLRAEKEGLTPKQLIERVWAEHKRDFDSFGVSFDNFYSTDSEENRQLSEKIYLALKDNGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDSCEVCGSTYLPTELLNPYSVVSGATPVRKTSKHYFFRLSDPRCETFLREWVSGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCDRKGIDFDAWIRAGSSAEQYHFIGKDILYFHTLFWPAMLQFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLREAIPQIAAHYEAREYGRALRHTMELADEVNAYVDGAKPWELAKDPANAVALHETCSVSLEAFRLLSLALKPVLPRVAEAVEAFFGIAPLAWADAAKPLSSAQPIKAYQHLMTRVDAKQIEALLAANRDSLQADATAAGGAGAATAKGAKAAKADAKPVSAKAPAANGADDATISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYILEPHSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_CANDC
Sequence: MEKLSILTERQQTELNYAIIQYLQPLCQQDNHALLDQLSKILNIDQWTQESNNVEKVDNYLEKRWSTVLRLQKKIIDLENEISNLNNIINSSNSDNNGIVLSKDKINWIPKGTAKQSYQCENIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYKKPYYLATCSSDLTIKIWDEKFNHIRTLNGHEHTVSSIQFSPIDNSILYSVSRDKNIRVWDIFQGISLKSFVGHSEWCRDLDIVSSDNNGDFVLTCSNDQSARLSHASSGAGLAMIVGHGHVVETVKFLPALQANKILDEYITKNIEQFPTIPLELLKDKTYNQLGFKYCITASRDNTIKLWLIPPPKIAPHRPPLPSKYNNSQSWMIAELRGHSSWVKCLCVHPNGRFIISGSDDKTIKFWDLSSLLETGSVNVVKTIIGHDGFINDIDFARLKEASDSTPTSQEDLLKEVEKRMRCLFISGSADNSIKLWN
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: EXP16_ARATH
Sequence: MAINPLILLTIFPLFLLLSFTDAGIPRVFSGGSWQTAHATFYGGNDASGTMGGACGYGNLYSQGYGTNTAALSTSLFNSGQSCGACFEIKCVNDPKWCHPGNPSVFVTATNFCPPNLAQPSDNGGWCNPPRSHFDLAMPVFLKIAEYRAGIVPISYRRVACRKSGGIRFTINGHRYFNLVLITNVAGAGDIARTSVKGSKTGWMSLTRNWGQNWQSNAVLVGQSLSFRVTSSDRRTSTSWNIAPSNWQFGQTFVGKNFRV
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A16, AtEXPA16, Alpha-expansin-16, At-EXP16, AtEx16, Ath-ExpAlpha-1.7.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RBY1F_HUMAN
Sequence: MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPADAKNAAKDMNGTSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSSGGTRGWLPSHEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNHRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDYAYRDYGHSSWDEHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTSHGAPPARGPRMSYGGSTCHAYSNTRDRYGRSWESYSSCGDFHYCDREHVCRKDQRNPPSLGRVLPDPREAYGSSSYVASIVDGGESRSEKGDSSRY
What is the function of this protein?
RNA-binding protein which may be involved in spermatogenesis.  Required for sperm development, possibly by participating in pre-mRNA splicing in the testis.
What are the official names of this protein?
RNA-binding motif protein, Y chromosome, family 1 member F/J, Y chromosome RNA recognition motif 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCKA_BACAN
Sequence: MSTVNVQIGLHELLNGSNAQIQLSVPQLVEKVLMRNEGKLTSTGAVSASTGKYTGRSPKDKFIVKEASVADKIAWGAVNQPISEEHFNKLYTKVLEYLKEKEELFVFKGFAGADRNYRLPIQVINEYAWHNLFVHQLFIRPTEEELTTHESEFTIVSAPNFKADPAVDGTNSEAFIMVSFEKRIVLIGGTEYAGEMKKSIFSIMNFLLPEQDILSMHCSANVGEEGDVALFFGLSGTGKTTLSADPNRKLIGDDEHGWSDNGVFNIEGGCYAKCVNLSHEKEPQIFDAITFGSVLENVIINDQTRIADYNDTTLTENTRAAYPMHAIDNIILPSVAGHPNTIIFLTADASGVLPPISKLSKEQAMYHFLSGYTSKLAGTERGVTSPQATFSTCFGSPFLPLDASRYAEMLGEKIEKHDAKVFLVNTGWTGGEYGVGKRMNLGYTRAMIQAALNGELAKTETAKHDIFGLEVPLHVPGVPDEVLMPEQTWADKAAYKAKAIELANEFKANFKKFDSVSEDIINLGGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX41_KLULA
Sequence: MNVFDGSDEEDNNPFSGTTHLYASGIAAVTDGPDDYDFTEPSINGSSDENAQSNAVAEPIEETDEPAEEIDDDTLQTWRFASAELSRSSAFETSYTNLLGQGKNPEVIRIVDAGQYRDIYGKYAIGYKIEFGGIVVTRRYSEFDSLRQSLCRLLPTIIIPPIPSKHPIIKYLFNPLHAKKDIKIIERRQRLLSRFLNNCHKVREIRNHIVFQKFLNPEYFWKEVLNTPPISILPMNNLLAPPLNPTKPSPIHLLLPTPTVLTMRKHEQLIGRNDVMEIKFADYDSDLIRYKAILQPLNKTVRSIRSNIQTYSAVLSELGAYFNAFSLENSVFQVSALFEQMNRLSMGIEKTGQAIDVNYVSAEIFSEAIMISLEEGSKEMLQFIHEAQRVLHFRNFKQEQFYTIETTIKKRKDRIRELKEADLQAVRLGEALKLNAEESPTVAQVMDSMTRKSANKNHTDKQIMGLFRSSASPNNKSGSDSISSEVEPHLLTKDERVVQVNKLEKELEKLNECFKLIEKDLQQVNESMDNSLNNLEKYFHEKWFLIFRELAHNITSWLKDCSESWKNAKQSIDSI
What is the function of this protein?
May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.
What are the official names of this protein?
Sorting nexin-41.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures.
Protein: OTCC_HALSA
Sequence: MEHLVDINDVESEEIEQLLDLAASMKENPGEFSGVMDNKSLVMLFAKPSTRTRLSFETGMTQLGGHGIFFEMGSSQLSRGEPISDVSQVMSRYEDAIMARLFEHDEMMELAENADVPVVNGLTDFLHPCQALTDMFTMQEKDRLDTLAFVGDGNNVAHSLMQASAKMGVDCRIATPEGMEPDEEIQDRVSDANVTVTNDPYEAVDGATAVYGDVFVSMGEEEQREEKLAEFDGFQIDQDLMDAARDDAIFMHCLPAHRGEEVTAEVADGPQSVIFDQAENRMHVQKAIVHTLVNQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, cOTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO1_GEOSE
Sequence: MKNKLVLIDGNSVAYRAFFALPLLHNDKGIHTNAVYGFTMMLNKILAEEQPTHILVAFDAGKTTFRHETFQDYKGGRQQTPPELSEQFPLLRELLKAYRIPAYELDHYEADDIIGTMAARAEREGFAVKVISGDRDLTQLASPQVTVEITKKGITDIESYTPETVVEKYGLTPEQIVDLKGLMGDKSDNIPGVPGIGEKTAVKLLKQFGTVENVLASIDEIKGEKLKENLRQYRDLALLSKQLAAICRDAPVELTLDDIVYKGEDREKVVALFQELGFQSFLDKMAVQTDEGEKPLAGMDFAIADSVTDEMLADKAALVVEVVGDNYHHAPIVGIALANERGRFFLRPETALADPKFLAWLGDETKKKTMFDSKRAAVALKWKGIELRGVVFDLLLAAYLLDPAQAAGDVAAVAKMHQYEAVRSDEAVYGKGAKRTVPDEPTLAEHLVRKAAAIWALEEPLMDELRRNEQDRLLTELEQPLAGILANMEFTGVKVDTKRLEQMGAELTEQLQAVERRIYELAGQEFNINSPKQLGTVLFDKLQLPVLKKTKTGYSTSADVLEKLAPHHEIVEHILHYRQLGKLQSTYIEGLLKVVHPVTGKVHTMFNQALTQTGRLSSVEPNLQNIPIRLEEGRKIRQAFVPSEPDWLIFAADYSQIELRVLAHIAEDDNLIEAFRRGLDIHTKTAMDIFHVSEEDVTANMRRQAKAVNFGIVYGISDYGLAQNLNITRKEAAEFIERYFASFPGVKQYMDNIVQEAKQKGYVTTLLHRRRYLPDITSRNFNVRSFAERTAMNTPIQGSAADIIKKAMIDLSVRLREERLQARLLLQVHDELILEAPKEEIERLCRLVPEVMEQAVTLRVPLKVDYHYGPTWYDAK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: DCD_PSEA8
Sequence: MTIKSDKWIRRMAQEHGMIEPFVERQVRGADDSRVISYGVSSYGYDVRCAAEFKVFTNIHSAVVDPKNFDEKSFVDINSDVCIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLQSDEACEVSYKDRGGKYQGQRGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: MECA_STRPN
Sequence: MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEVKEEEQEQAEQEAESKKEPYIYYILSFAKLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLNLQKIG
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: RL36_HYDHA
Sequence: MAIRYPMAVGLNKGHKVTKNVSKPRHCRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: FOXD4_MOUSE
Sequence: MNSARAGHLRSTPPPSPLSSDQDEVEIDVLAEEEDGDQTEEEDDEEESHKCLERSLQRPGARTLAGRSAGDCGDLSNSSGFLRKFRAPRTPATTTADGPQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHHPPSGGHPHCPFPPPAVPATLHVSQPSLLLRYSAPPQPNLAAHPAAPPRSHPCAPLHPHPMRYLLLAAPAYGDNPRKAEGADPATPLAIPALQPVLGSQPWERDQSSGTRSGRGCASFTIESIMQGVTGGGTGSAQSPSFAPWSYCHLLQHPPCLLHPQAASPLFHMSAGSRTILPQQPQPPLPLQQEQHHCAISCAPGKGVRLGQHLSAVAALLRQQPAADDGRLTTLAALSGREGTLPEF
What are the official names of this protein?
Forkhead box protein D4, Forkhead-related protein FKHL9, Forkhead-related transcription factor 5, FREAC-5, Transcription factor FKH-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: GTFB_STRAG
Sequence: MIILFDFFDKKSKDLYYSLITSGLHGNAVVINDDGFLPQNINSPYSFFCNMEGKNGNPLYFNQVPLPDLWEIKGNNIEAEIWDFSIKRAKIFYQEPKYKRQVKNIDWFDNNKKVRYTDHYNRFGWCFARTHFDKNQNVTTKSYFDKDGKEVIVENFRTGVIILNWLNKDYFFDNRVAFLNFYFSLMGWNLSRIWYNSLSTPFFVSYRMTYPGEDILFWQEDIEDTIPANMRVLLESTNTRTQKVIVQKKNTYHKIKSMLPKEQQEKIGYLGFIYPNKKNNKGRKDIFILTNSDQIEHLEVLVHHLSDYHFHIAAYTEMSFKLMSFSQEQNVTLYPNISRTDLDNLFEICDIYFDINHGNEVDDVIRRAFEYNHLIFAFDNTCHNRELVLDSNIISHTTCEQLINLMKNLSGSIMYLLEQQREQTSNETKERYKEILGGYGNA
What is the function of this protein?
Required for the polymorphic O-glycosylation of the serine-rich repeat protein Srr2.  A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat proteins, probably Srr2 in this organism.  The GtfA-GtfB (Gtf1-Gtf2 in this bacteria) complex adds GlcNAc from UDP-GlcNAc to Srr2 substrate, attaching the first sugar residue.  Stabilizes the glycosylation activity of GtfA in vivo.  Upon expression in a gtfB deletion mutant of S. parasanguis, GtfB confers incorrect glycosylation and partial complementation of a biofilm formation defect, while GtfA/GtfB restores correct expression of serine-rich repeat protein Fap1 and completely restores a biofilm formation defect in a S. parasanguis double gtfA-gtfB deletion.
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase stabilizing protein GtfB, Glycosyltransferase chaperone Gtf2, Glycosyltransferase stabilizing protein GtfB, Glycosyltransferase-stabilizing protein Gtf2.
What is the protein family that this protein belongs to?
Belongs to the GtfB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MUSK_CHICK
Sequence: MRDLLVVPLGHVLTLAALSLAETLQKAPFISTPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNGQLLTILSVEDSDDGVYCCTADNGVGAAAQSCGALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKENARIAVLDSGNLRIHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTWLENGKAVSAGSIAESVKDRVVDSRLQVYVTRPGLFTCLATNKHSKTFGAAKAAATISVSEWSKLYKGDAGYCSTYRGEVCSAILSRNALVFFNSSYADPEETQELLVHTAWTELKTVSSFCQPAAESLLCNYIFQECKPSGVGPAPKPICRENCLAVKDLYCFKEWLSMEENSQRGIYKPGLMLLALPECNRLPSLHQDPSACTHIPFFDFKKENITRTCYSGNGQFYQGWANVTASGIPCQKWSDQAPHLHRRTPQVFPELSDAENYCRNPGGENERPWCYTKDPSVTWEYCSVSPCGDASLSLGTRKPNGETQNLPPPPSYSPTYSMNVIILIISSFALIVILGIITLVCCRRRKQWKNKKRESETPTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLCWSKLPADRPSFASIHRILERMYERAVASPQV
What is the function of this protein?
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle.  Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex.  The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane.  May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
What are the official names of this protein?
Muscle, skeletal receptor tyrosine protein kinase, Muscle-specific tyrosine protein kinase receptor, MuSK, Muscle-specific kinase receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Single- pass type I membrane protein. Note=Localizes to the postsynaptic cell membrane of the neuromuscular junction.
Protein: Y08A_UREPA
Sequence: MYNYKEVKHMGYGKGYLAMFKNKKVRFKVVNSFPDLKVQFVTSFPDYKVKISNSSSFCEETIKIQVVTSFPDVKLQKVTSFGDFEAYID
What are the official names of this protein?
Uncharacterized protein UU089.1.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 slr1025.
Protein: CAE11_LITRO
Sequence: QQDYTGWMDF
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
What are the official names of this protein?
Caerulein 1.1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: METAA_CAMJE
Sequence: MPLIIPENIPAYELLKEHAFIMGLRRAKHQDIRPQEILIVNLMPKKIETENQILSLLANSPLQVNITLLATTSYVGKNTPFTHLEKFYKGLEEVKKHKFDGAIVTGAPVEQMDFEKVAYWEELLEIFDFLKQNVTSSMYICWGAMAALKYFYGVDKISLDKKIFGVYKHDKVSPDLLLTNLDEKVLMPHSRHSSMDEEQILALQKQGKLKILLRNKKIGSALLRDEKNIFILGHLEYFKETLHQEYVRDNFIQKAKNYYDKKGNIKYNWRSNANTIFANWLNYDVYQSTPFVL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMB_SALHS
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERARSLGITHIISSDLGRTKRTAEIIAQACGCDITFDSRLRELDMGVLEKRQIDSLTEEEEGWRRQLVNGTQDGRIPGGESMQELSDRVHAALASCLELPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRIDYQESQWLASGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: SYK_ONYPE
Sequence: MATKLSEQEIIRHQKMNELKKINIDPFGKKFVPSHSIEQILLQYQKADSLALEQSQIHVCVAGRIVLKRGQGKAGFLHLQDFNFRMQAYIKLDLVGKDAFQIYQNCDLGDIIGIKGFLFKTKTQELTIKALEFIHLTKALKPLPDKFHGLQNREEMRKNRYVDLIVNEKTRQVFLTRSLIMKYIRNFFDNQGFLEVETPILQPTLGGASAKPFITHHNALNCDFYLRIATELPLKKLIVGGMNKVYEIGRLFRNEGIDATHNPEFSTIEAYLAYADMQDIMDLTKQCLQELAQKLFGKLQFTYQNQEIDFSHFAKVSMVASIKEKTGIDFTDNFTLEQCLSLAKKHQIEVMPHFSQGHIIEAFFGKYVENTLIQPTFVYGHPLEISPLAKQNEADPRFTDRFELFIVGKEFANAFSELNDPIEQEKRFLNQLQQKQLGNDEANDMDYDFLNALNYGMPPTGGLGMGLDRLVMLLTDTANIRDVILFPHCKNQNKFSQNKTANKVLTNNDNE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_EISEL
Sequence: DKDTYKVSGGLHGVGVSCVNALSSLLVATVHREGKVFQQKYSTGNPQGAVEVVGQSDRTGTTIYFEPDATIFATTEYKYETVSKRLRELSYLNKGIRLTLTDLRETDEQGRHLYEEFFSEGGLKEFVEHLDSTRQPLLPAPIHVEKTDGDIPVEVALIYNNSYSENVFSYVNNINTHEGGTHVSGFRRALTRTLKSYADKSGMLEKAKVEITGDDFREGLTAVISIKVAEPQFEGQTKTKLGNSDAIGAVDNAVSEILGYYLEENPREAKLIIQKVILAAQARQAARKAREMVQRKNVMGGTSLPGKLADCSDTNPERCELYLVEGDSAGGSAKQGRDRSFQAILPLRGKILNVEKAQEYKIYDNEEIKNMITAMGVTFGTEEDSKALNLTKLRYHKIIIMTDADVDGSHIRTLILTFFFRYMRELIEQGYLYVALPPLYIVKKGKEERYAWSDAERDAIIREIAPEGKEDSVGIQRY
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITG2_SALCH
Sequence: MMPIPANPTNASIQPQSLYDAWADLAWRAMLTEVNLSPKPGLVDRLNCGAHKDMALADFHRSAEAIRHWLPRFMEYGASCTRLPPESVLAGLRPLGMACEAAMFRATAGVNTHKGSIFSLGLLCAAIGRLYQLRQPITAETLCATAADFCRGLTTRELRQNNLQLTAGQRLYQQLGLTGARGEAEAGYPLVIRHALPHYRALLAQGRDPELALLDTLLLLMSLNGDTNVASRGGADGLRWLQQQAAVLLHQGGIRTPDDLVYLHRFDQQCIERNLSPGGSADLLIVTWFLAQISQVNH
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 2, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: Y623_MYCPN
Sequence: MDSTFNELGVSPALIATLKDNNINQPTTIQQLAIPQFLQHQNLIVHSPTGTGKTAVFGIPVIETLLKKPSKGTTQTLVVAPTRELAEQIKTTFINFAKHTHLKVVSLIGGIPIWQQLKQLENQPEIVVGTMGRVMDLLERGVIKFEHLEHLIIDEVDLMLDRGFKRKLFDLLSRIEKFEQIAVYSASYNEETIETAKQITKNGIFLAAPELKQNAPEPDNKLIDQFVCYLFSNRKKQALYSLVSQTRAKSIIVFCDTKKLVDELCIFLRKNDVKTYPLHGDKAQFIRERNLKLFANTTAPIVLVTTDLIGRGIHVEGVDMVVNYSACVNFETYLHRMGRTGRNNHKGSCITFCTSHEKQAFLKLLEQVNDKRISPLRPMRLRLIPLKCKTQPKKGKLSLQSVQKIYVNPRSNGTFKRVPLAGDLFKSRMRQPERDMQKNKLHDSDWQSNM
What are the official names of this protein?
Probable ATP-dependent RNA helicase MG425 homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: RS8_XYLFM
Sequence: MSMTDPIADMLVRIKNAASVGKPNVRFPFSKVKLAIALVLKHEGYIFDAKVIQGDNSKSDIEVVLKYFEGRPVIRILKRVSRSGLRKYCGKAELPKVLGGLGVSIISTSKGIMTDSKARESGVGGEVLCFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.