PharMolix/UniProtQA huggingface dataset:
Protein: GLYCO_SYNV
Sequence: MSHIMNLLVISFVLAGSSWSLLGYQDDFSSKRSGALASNPTYNLPQDKGYGRDMYQPYYICEPDNDGSALTLPSWHYSCKESCMGNHLKRVVNITGARWNYVGISIPVFKIVTNEVCYTSHENVWGYCSQYQISRPVATQKSDVSCITSSMWDNDKSPIGSLYNIVNSNEAECDYFSDITDCNRDYQIFKREGKLIKRSDDSPLELSIVTDGIRTDPASEYLSLDDVSWFWKLPNNDMSPPCGWEKTQKLSCSYTDTTDVIKCNSIGYTYNIQGISKKSTCAGNIYDTDGPFPFFYDAEEALMSTDDACGKAKQGKPDADIAFIEGVNRAFEDLELTYCSATCDLFARQGTPNEDHVLDTPIGTWRYVMRDNLDPALVPCLPTSNWTISDPTTICHGKDHILVVDTATGHSGSWDTKKDYIITGEVCNTNNDEMGDDYDGMRDKILRGETIEIKFWTGDIIRMAPPYDNPEWIKGSVLFRQNPGWFSSVELNKDMIHTRDNITDLLTVMVQNATAEVMYKRLDPKTMKHILFAEIVDGVGNVSGKISGFLTGLFGGFTKAVIIVASLAICYIVLSVLWKVRLVASIFNSAKKKRVRISDILDEEPHRIQQSRPTLSRKKKTRESIQMLLNDI
What is the function of this protein?
This protein forms spikes on the surface of the virion.  It is responsible both for the binding of the virus to susceptible host cells and for inducing the uptake of the virus by the cell.  The interaction between the internal components of the virion and the portion of the glycoprotein exposed on the cytoplasmic face of the plasma membrane probably directs envelopment and virus budding.
What are the official names of this protein?
Spike glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: MG101_KLULA
Sequence: MLGFRHVIRATSKRFATSGTSMVRKTVTSGNSNAIRSATSNVVPPASSAAAASAPSTIKRVPGYNKTLEDSLNGTILENPVETQATQSSNEINWYTSYHGIGSKPFSDETQNALSSALNADDIEIKPDGLIYLPEIKYRRILNKAFGPGGWGLVPRSETIVTAKLVTREYALVCHGQMVSIARGEQDYFSETGIPTATEGCKSNALMRCCKDLGIGSELWDPVFIKQYKKKHCTEKFVEHVTTKKKKKIWLRKDREVEYPYK
What is the function of this protein?
Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome.  Binds to DNA (By similarity).
What are the official names of this protein?
Mitochondrial genome maintenance protein MGM101.
What is the protein family that this protein belongs to?
Belongs to the MGM101 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: ISPE_SHESA
Sequence: MSNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSNMSAVVADSDNLILRAAKSLQQATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQLWNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQAVTPTEFWYLVIAPDAHVSTAAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTGACVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NRDI_SALSV
Sequence: MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCGVPWLYRFELMGTQRDIDNVRKGVNEFWQQLSRSA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: Y3917_YERPB
Sequence: MIIPWQQVDSETLDNLLEAFVLREGTDYGEHERSLTEKVADVRRQLVSGEAVLVWSELHETINIMPRGSFHAGAEEQQ
What are the official names of this protein?
UPF0270 protein YPTS_3917.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: RNP2_METBF
Sequence: MKRLLPSLRAKKRYLAFELISEVPVSRSDLVKEVMFSASSLLGDVTASECDIKVLGFEESKGIIQCAHTKVKETRASMATLTRINGKRATVHILGTSGTIKRATEKFLQNTAFEPEIRINPKRLKNNNLSRVQES
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC21_YARLI
Sequence: MSYNGIGLSTPRGSATSGHIQTNISNRAFQSTNHRGEFAHHEMTDEQDKRLNKKLDRDYAADRQADVELLEHERKRKVEVACMELQDKLEEEGQKGEEEIEEEVNTLRRQLTLKMARELDVRTTIVSADREALRKNYHKAAVIKQQEMDRMRDAFDTTKNLDDRGRDRPRNRQRQNREKSPVRDTRRSRSARERSPSRRGRRPRRYSVTEDVRTSEVISERQGSGSPCRRADSRSRSRSPERGSRRKSYRERSRSRSRERSERRGRRDSVREREQDRSRSPLPY
What is the function of this protein?
Involved in pre-mRNA splicing.  May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome.  May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC21.
What is the protein family that this protein belongs to?
Belongs to the CWC21 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IXTPA_BACLD
Sequence: MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISKETGKIVIADDSGLSVDYLGGSPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFRCALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFLVKDKDQTMAELSSGEKNKISHRAEALKKLSALLDQA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: DNAK_HELAH
Sequence: MGKVIGIDLGTTNSAMAVYEGNEAKIIANKEGKNTTPSIVAFTDKGEILVGESAKRQAVTNPEKTIYSIKRIMGLMFNEEKAKEAEKRLPYKIVDRNGACAIEISGKVYTPQEISAKILMKLKEDAESYLGESVTEAVITVPAYFNDSQRKATKEAGTIAGLNVLRIINEPTSAALAYGLDKKESEKIMVYDLGGGTFDVTVLETGDNVVEVLATGGDAFLGGDDFDNRVIDFLATEFKNETGIEIKNDVMALQRLKEAAENAKKELSSAMETEINLPFITADATGPKHLVKKLTRAKFESLTEDLIEETISKIEGVIKDAGLTKNEISEVVMVGGSTRIPKVQERVKGFINKELNKSVNPDEVVAVGASIQGGVLKGDVKDVLLLDVTPLSLGIETLGGVMTKVIDRGTTIPAKKSQVFSTAEDNQPAVSIMVLQGERDLARDNKSLGKFDLQGIAPAPRGVPQIEVTFDIDANGILTVSAQDKNTGKSQEIKISGSSGLSDSEIEKMVKDAELHKEEDARKKEVIEARNHADSLAHQTQKSLDEHKANLNENDANEIQNAINALKDCIKNDNATKAELEDKTKALVQAAQKLGEAMANKNNAEQPKKKDDDVIDAEVE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: P4A_FOWPN
Sequence: MMLIKNIVTLDQLESSDYLYKLISSVLPSLCLDYKIDPKLANGYVHALDTIYSPELISILTDGERSQQLDTLGINYILSRKNDLGIYFPINIRENGEIVSTWNKNTGGYTNPIPCTISFNDLPPFTKILIQIRTMGCEAHARYFGGYVEHPSSPNILSPKINPNISFANSYIHSLTYPYIEGRADYSTYRPLLINGIMEKKDLANLLNVRALLEPMSRAIFDAIFKIQFHCNANNIVLVQNPNIDTDLITMQTLKYLVMYFQHFSGFTLRDIYLGGVRIRVDNSMLASYVVSIYFSKEIKYIEDNKLFSLDYIDQFVFRPDNSNLNITVTAQQLGIRILNMTSNRPYIINLLNIVSKSLVRHRNVPKEISLFWDGMSYDEYKNMKFIDMMFLGTTCYLFALYNKNGITYCSMLNDVLRAEETPIRICVFPRILKGKTIPTLIREILENINNISVRDFPKYDTHDVKHIGLSDAGFMLFFQFLRLMENKEPHIAVKEILMAYTGIKIDDKGSPYYITPESYRTFIFMLFKAMGFNVRVNRTTISSHSYTSYYVSPRVSKRYLTNMLQKASCSQSEAEKLLSSAHDLVSFMLSVNNSSNRDSYRRINRSFFGGFKESASEEDATLVQFISPVNILDRINVKGILSANALNEIMDTDVFLPENANFKENLKQLLKEDTIDGKSIAHIIPLNTIDRLIVSAGGVSVGELLENLDERVPDENATNEVIELITNALKDRNMKDSNFIATNILNSITQISEKQMDGIKKITCHGTMMFKELAMHIYFTERYFKAKISDDVKISILEKYRDFIELSKSLYKDLIGIDQIKSVLSIVHRTGRNIDDNPITQEDIQKAYNIARPKILKLTNYYTEMTKSYFENIKRIMNPEDANAVVFDNE
What is the function of this protein?
Core protein 4a is the most abundant virion protein.  Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition (By similarity).
What are the official names of this protein?
Major core protein 4a precursor, p4a, Virion core protein 4a precursor.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein P4a family.
What are the subcellular locations of this protein?
Virion. Note=Probably localizes to the virion core wall.
Protein: ATF7_HUMAN
Sequence: MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR
What is the function of this protein?
Acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities.  It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-7, cAMP-dependent transcription factor ATF-7, Activating transcription factor 7, Transcription factor ATF-A.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Chromosome, telomere. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery. SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm.
Protein: HEM11_CUCSA
Sequence: MAVSTSFSGAKLEALLFKSASNSSSTRNLSSSHLPGFCKSIRTRRILFQRTGVSSFTPFKCELASSDVLVQNDEIDPPKSSNLSALEQLKTSAVDRYTKERSSIVVIGLSIHTTPVEMREKLAIPEAEWPRAIGELCGLNHIEEAAVLSTCNRMEIYVVALSQHRGVKEVTEWMSKTSGIPVSEICQHRFLLYNNDATQHIFEVSAGLDSLVLGEGQILAQVKQVVKVGQGVAGFGRNISGLFKHAITVGKRVRTETNIAAGAVSVSSAAVELALMKLPEPSHATARMLVIGAGKMGKLVIKHLVAKGCTKMVVVNRSEERVTAIREEMKDVEIIYKPLTEMLSCTAEADVIFTSTASESLLFTKEQVKDLPPVGHDVGGLRLFIDISVPRNVGACINNLEDVRVYNVDDLKEVVAANKEDRLRKAMEAQSIITEESKQFEAWRDSLETVPTIKKLRAYAERIRTAELEKCLSKMGDDIPKKTRRAVDDLSRGIVNKLLHGPMQHLRCDGSDSRTLSETLENMHALNRMFSLETEIAVLEQKIRAKVEQNQK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 1, chloroplastic, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: E25_NPVAC
Sequence: MWGIVLLIVLLILFYLYWTNALNFNSLTESSPSLGQSSDSVELDENKQLNVKLNNGRVANLRIAHGDNKLSQVYIAEKPLSIDDIVKEGSNKVGTNSVFLGTVYDYGIKSPNAASTSSNVTMTRGAANFDIKEFKSMFIVFKGVTPTKTVEDNGMLRFEVDNMIVCLIDPNTAPLSEREVRELRKSNCTLVYTRNAAAQQVLLENNFTVINAEQTAYLKNYKSYREMN
What is the function of this protein?
Plays a role in the production of infectious budded virion (BV) and occlusion-derived virion (ODV) formation.
What are the official names of this protein?
Virus envelope protein E25, Protein E25, Virus envelope protein AC94.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p25 family.
What are the subcellular locations of this protein?
Virion membrane. Host nucleus. Note=Associated with the envelopes of virions present in the nucleus of infected cells, with the envelopes of virions in the process of being occluded and fully occluded virions.
Protein: LSPA_THEYD
Sequence: MSLKLYKTSISIFLILLIDQITKYLAIKFLSPDGIVKLLPFLNLVYVENTGTAFGMFKFLGSGFFIIIALVVTGFLVYMYFKDTQNWFIYSLIIAGALGNIIDRLIYGYVIDFIDLHLKNLHWPAFNVADSAISIGIVLFVYKNLKK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_RHOPS
Sequence: MSITAERKAEVIQGNANKAGDTGSPEVQVAILSERIVNLTAHFKTHTKDNHSRRGLLKLVSTRRSLLDYVKKKDEARYKALLEKHNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RNP3_ARCFU
Sequence: MYDFLRFFPENLPDLGFKSYVFMLEKPKGCGIVIRANSPEELRKKLRGVKRRAIVGIIGKEAVCREAVMRRRVDVILDWEDRELDYATLKLAAEKDVAIELSLSKFLRTEGYKRMHLFERLRQEIMVIRKFDVPFIVTTAAENQYELRTRKQVETFFKFFGAEIPKARLYAQRLVRRYFDENYIMDGFEVEQLSNSGVV
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SANT_PLAFW
Sequence: MNRILSVSFYLFFLYLYIYKTYGKVKNTDHELSNIYGIKYYLRNGLSDKKNGKGQKYQDLEEDENDDEEDSNSEESNNDEENKLIEGQEGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGDKGPNSDGEHSRSKNDNKKKKSKKNIINMFIGM
What is the function of this protein?
S antigens are soluble heat-stable proteins present in the sera of some infected individuals.
What are the official names of this protein?
S-antigen protein.
What are the subcellular locations of this protein?
Parasitophorous vacuole. Note=Localizes to the cell periphery in early schizonts and then to the parasitophorous vacuole in late schizonts. Following schizont rupture, the S-antigen is released in host sera.
Protein: CINAL_ECODH
Sequence: MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVGDNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMERYFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVMVEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPIIELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQFTGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEHLNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEVVESMTLSV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PDXA_METC4
Sequence: MASDDRPLALTLGDPSGIGPEIALAAWQLRSERGVPPFQLIGDPEFLEATAYRLGLSVPVAEVEPDDACEVFPRALPVLPLPSGAKVIATPGAPDSANAGAIVESITAAVDLVRSGAASAVVTNPIAKFVLTRVGFAHPGHTEFLAALAAREGREPSLPVMMIWSDTLAVVPVTIHVALRRVPELLTQDLVERTARIVHADLRARFGLEHPRLVLSGLNPHAGESGTMGTEDRDVLAPAVAVLRSEGIDIRGPLPADTLFHERARATYDVALTPTHDQALIPVKTLAFDEGVNVTLGLPFVRTSPDHGTAFDIAGKGLAKPDSLIAALRLAHRLAHRPADTVLPFPARA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_METS4
Sequence: MANVVVVGAQWGDEGKGKIVDWLAEQADVVVRFQGGHNAGHTLVIDGVTYKLSLLPSGVVRGGTLSVIGNGVVVDPWHLVDEIARIGTQGVSITPETLRIADNATLILPLHRELDHFRETANATLKIGTTKRGIGPAYEDKVGRRAIRVVDLADEALLGAKIERLLAHHNALRRGLGIEEVDGAALKAELLAIAPKILPYADTVWVLLDEARRGGQRILFEGAQGALLDVDHGTYPYVTSSNIVAAQAATGSGLGPSAIGYVLGIVKAYTTRVGEGPFPTELTDAIGEKIGERGREFGVVTGRKRRCGWFDAALVRQTVRTSGIDGIALTKLDILDGFETIKICTGYRLDGRLIDHLPASQADQARVEPVYETIDGWFETTAGARSWAELPAQAIKYVRRIEELIGATVALLSTSPERDDTILVHNPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_HELPG
Sequence: MITLKQALSLSQDELETLKNEIDAKVRASDLNAYIKAPSLNGASAKGVPILIKDNISVKGWEITCSSKILKGYVAPYHASVMENLHQNSMAGFGLSNMDEFAMGSTTESSCYGITKNPRDKNRVPGGSSGGSAAAVAGGLAVAALGSDTGGSIRQPASYCGCVGLKPTYGRVSRYGLIAYCSSFDQIGPITQNVEDASILFDAISGHDNKDSTSANLKPTQTFKNLNKDKRFKIAILRDHIKDASSEVQLAYENTLKALKEMGHEIVEKKMLDSHYQISIYYIISMAEASSNLARFDGVRYGRRAQNIKDLKELYLKSRSEGFGDEVKRRIMLGNFVLSSGYYDAYYLKAQQMRLIIKEQYNKIFEEVDLIFTPVAPTSAHLFNYHASPLEMYLSDIYTIGANLSGLPALSLPVAKDPLGLPIGMQFIAKAFDEQSLLDISYALEQELDLKLD
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: KGX14_CENSC
Sequence: DRDSCVDKSRCAKYGYYQECQDCCKKAGHNGGTCMFFKCKCA
What is the function of this protein?
Blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 1.4, CsErgTx1, CsErg1, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_CHLL3
Sequence: MTLIQAILLGIIQGLTEFLPISSTAHLRIIPALAGWEDPGAAFTAIIQIGTLGAVMLYFRRDILSIVKSVATGLWKGNPLHDGEAKMGWMIAAGTLPIVAFGLLFKHEIETTLRSLYWISGALIILALVLSLAEWKIKKRLEEGHPLKSMEDIGWKEALLIGLAQAIALIPGSSRSGTTITGGLLLNLSRETAARFSFLLSLPAVFAAGAFELYKTWDLITADPGNIMNLAVATITSGIVGYLSIAFLLNYLKSHTTSIFIAYRLAAGAGLLLLLGGGTILP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBL3_HUMAN
Sequence: MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFLWHNMKLPVPAAAPTPWETHKGALP
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Transducin beta-like protein 3, WD repeat-containing protein SAZD.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y3288_YERE8
Sequence: MYDNLKSLGITQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVADNAGHGYKEINEINPNLRYVIDELDQLCKRDQVEVDLKRKILDDLRHLESVVTNKIAEIEADLEKLTSGR
What are the official names of this protein?
UPF0325 protein YE3288.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: HPS2_PITAZ
Sequence: LRPAFIRPKGK
What are the official names of this protein?
Hyposin-H2, HPS-H2, Hyposin-2, Hyposin-HA2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Hyposin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDRGK_OSMMO
Sequence: MDIVLYFVAVPILIVLIVSAVKVRGKTEEDNHEARQEVAAQVVGRLQAEEGSNRLRRRRNLNRMMANRMANSAYREAADNDSPVEVEEEYEEAEQQSQATGKRGAKKQKKLEEKQAKRAQREAELEEREERKRTQELREEERRKEDKKERILEQRQEEEELRAKEEQEKREEEEYLCLKQSFVVEEQGEADELTEQESQNLLQEFIQHIKDCKVVLLEDLASHFGLRTQDAISRLQDLLSDGSITGVIDDRGKFIFITPEEMNVVAQFIRQRGRVSITDLAQASNSLINLIPEIHNTA
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy).  In response to endoplasmic reticulum stress, promotes recruitment of the E3 ufm1-protein ligase ufl1 to the endoplasmic reticulum membrane, leading to ufmylation of target proteins and subsequent reticulophagy of endoplasmic reticulum sheets (By similarity).  Plays a role in cartilage development through sox9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (By similarity).
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane. Note=Localizes to the endoplasmic reticulum membrane in response to endoplasmic reticulum stress.
Protein: MCH_RAT
Sequence: MAKMSLSSYMLMLAFSLFSHGILLSASKSIRNVEDDIVFNTFRMGKAFQKEDTAERSVVAPSLEGYKNDESGFMKDDDDKTTKNTGSKQNLVTHGLPLSLAVKPYLALKGPAVFPAENGVQNTESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV
What is the function of this protein?
NEI can influence differentiation of neuronal processes in brain neurons.  Affects the content of neurofilament protein in neuritogenesis (in vitro).  May also be a neuromodulatory factor.  In behavioral tests, it stimulates exploration and anxiety when injected into the ventromedial nucleus.  Also stimulates grooming, locomotion and rearing.  May antagonize the inhibitory effect of mch on ACTH release.  Reduces dopamine and dopac release in the ventromedial nucleus.
What are the official names of this protein?
Pro-MCH.
What is the protein family that this protein belongs to?
Belongs to the melanin-concentrating hormone family.
What are the subcellular locations of this protein?
Secreted.