PharMolix/UniProtQA huggingface dataset:
Protein: CDPK3_ORYSJ
Sequence: MGNCCRSPAAAAREDVKSSHFPASAGKKKPHQARNGGVGGGGGGGGGGGGGGGAGQKRLPVLGEEGCELIGGIDDKYALDRELGRGEFGVTYLCMDRDTKELLACKSISKRKLRTAVDVEDVRREVAIMRHLPKSASIVSLREACEDEGAVHLVMELCEGGELFDRIVARGHYTERAAANVTRTIVEVVQLCHRHGVIHRDLKPENFLFANKKENSPLKAIDFGLSIFFKPGEKFSEIVGSPYYMAPEVLKRNYGPEIDIWSAGVILYILLCGVPPFWAETEQGVAQAILRGNIDFKREPWPNVSENAKDLVRRMLEPDPKLRLTAKQVLEHPWLQNAKKAPNVPLGDIVKSRLKQFSRMNRFKRRALRVIADHLSAEEVEDIKEMFKAMDTDNDGIVSYEELKSGIAKFGSHLAESEVQMLIEAVDTNGKDALDYGEFLAVSLHLQRMANDEHLRRAFLFFDKDGNGYIEPEELREALVDDGAGDSMEVVNDILQEVDTDKDGKISYDEFVAMMKTGTDWRKASRHYSRGRFNSLSMKLIKDGSVKLVNE
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 3, OsCDPK3, OsCPK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: CCL3_MACMU
Sequence: MQVSTAALAVLLCTVALCNRISATFAADTPTSCCFSYISRQIPQNFIADYFETNSQCSKPGVIFLTKRGRQVCADPSKEWVQKYVSDLELSA
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.  Binds to CCR1, CCR4 and CCR5.  One of the major HIV-suppressive factors produced by CD8+ T-cells.  Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) (By similarity).
What are the official names of this protein?
C-C motif chemokine 3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Small-inducible cytokine A3.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CY550_PARVE
Sequence: MKISIYATLAALSLALPAVAQEGDAAKGEKEFNKCKACHMVQAPDGTDIVKGGKTGPNLYGVVGRKIASVEGFKYGDGILEVAEKNPDMVWSEADLIEYVTDPKPWLVEKTGDSAAKTKMTFKLGKNQADVVAFLAQHSPDAGAEAAPAEGAAN
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
Protein: DAPB_SINFN
Sequence: MSETDMKLVVVGAAGRMGQTLIRTVHEAAGVRLHAAIERSNSPFIGRDAGELAGLGPIGVPITDKPLEAFVEAEGVLDFTAPAGTVEFAGLAAQARIVHVIGTTGCSADDEAKIRAAARHARVVKSGNMSLGVNLLGVLTETAARALSAKDWDIEILEMHHRHKVDAPSGTALLLGEAAAKGRGIDLADQAVKVRDGHTGPRPQGTIGFATLRGGLVVGEHSVILAGEGELVTLSHSATDRSIFARGAVAAALWGRSQKPGFYTMLDVLGLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOAR_BACSU
Sequence: MIQILITGLFLLAQPSEPQDSLTVTQQGRTIATVNREDFTMPLPGTPMVDYEKYSKFIKQLDQKVYREPINAVLNDHGSIVPGRVGYKLYQQAFMEKFYAYFYGQGPSKIEVPEMNIYPKVDSELLAHISTQQLGQYVTYFNSSNKSRSHNISLSAKAIDNHVVFPNETFSFNQVVGMRTRNKGYKSAPIIVKGELSEGVGGGICQVSSTLFNAVDRAGLQIVQRYSHTRSVPYVPPGRDATVSWGGPDFRFQNQYNQPILIRAKRYGGSMIITLYSSDVINSRLRKIPKAPSRIPKEINAEQ
What are the official names of this protein?
Uncharacterized protein YoaR.
Protein: HIS7_ANASK
Sequence: MSRRATVKAPRAGAAARRGAVARRTKETDVAVELRLEPGEAAISTGLPFFDHMLDQISRHGGMALTVRAKGDLQVDAHHTVEDVGIGLGEALRQALEDKAGLARYGHAVVPLDEALVEAVVDLSGRPHLTFNAKLPSGKKFIGGYDVDLTQDFLQALVNHARICVHVNVRYGRNLHHVVEAIFKATARALRAATAREGTALPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KR16_ICHVA
Sequence: MTSSGFLRAHPGVVRRCGFTRGGGLKVGPCALTDPGLAWVHAYYTDEALNWLAGLDNPLWKSGADVMDLLPGDMYVSEHVFKKILSRVGPEFFDSFIPIREVEECILFGFSPLSSTGMAALKAIDLVYGGYAPAAPGIPMEVYAWEMAYKIGAAPRLLRWVLIEGEGIEQFATLAESGLRGSLRDYIGTHPSGCKTPMDLGLVVKNVHGLVAALGMLMDSNIYHGDLKIDNLTVTEPGGPYKLIDFEFAHPFEARMRPMIEARGPITWLMPGTPACNPPEHDEETPCRDRRMKELGVTWQLGLIMLETIVLDEALVRDENMEWKRPDFKRLVSAVMEENGSLAPHDPRLLEGYLDLIGECLKRDTAVRMDLVTLMTELSLLIEKFKL
What are the official names of this protein?
Protein kinase ORF16.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: MIAA_ROSCS
Sequence: MIPLLAIVGPTAVGKTALSLHLARLFDGEIVSADSRQVYRWMDIGTAKPTPAERATVPHHLIDVVDPDEDFSLALYQDMATAAIADIAARGKLPLLVGGTGQYLAAVLQGWQLPRVAPRPDIRAALERQASEQGGEALYARLKEVDPIAAARILPGNVRRIIRALEVYEATGIPISEQRSVQPPPYRITTIWLTLPAPVLYARIDARVEAMMAAGLLDEVRGLLERGYHWNLPSMSGLGYREFRPYFEGRATLEEAVTRLKYDTHTFARRQPAWFRRLPNIVTLPADAPDLLQRAEAIVRQTFDSS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SCX9_TITOB
Sequence: MNYSTLIAVASLLTAGTESKKDGYPVKEGDCAFPCGYDNEYCDKLCKERKADSGYCYWGNILCYCYGLPDKAAIKGYGRCRPGKK
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin To9, T-alpha* NaTx3.8.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAAF4_HUMAN
Sequence: MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
What is the function of this protein?
Axonemal dynein assembly factor required for ciliary motility.  Involved in neuronal migration during development of the cerebral neocortex.  May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
What are the official names of this protein?
Dynein axonemal assembly factor 4, Dyslexia susceptibility 1 candidate gene 1 protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Dynein axonemal particle. Cell projection, neuron projection.
Protein: DER_BRUSI
Sequence: MGFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQLIDTAGLEEAANDSLEARMRAQTEAAISEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANKAEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIVELLGEERVFAEERQEEAADEVFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTGPEAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADGLRAIRFAEVVIIVLDATIPFEKQDLQIADLIIREGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLRAVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLEGVIAHQPPPAVSGRRLKVKYMTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAKKKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: EBNA4_EBVB9
Sequence: MKKAWLSRAQQADAGGASGSEDPPDYGDQGNVTQVGSEPISPEIGPFELSAASEDDPQSGPVEENLDAAAREEEEPHEQEHNGGDDPLDVHTRQPRFVDVNPTQAPVIQLVHAVYDSMLQSDLRPLGSLFLEQNLNIEEFIWMCMTVRHRCQAIRKKPLPIVKQRRWKLLSSCRSWRMGYRTHNLKVNSFESGGDNVHPVLVTATLGCDEGTRHATTYSAGIVQIPRISDQNQKIETAFLMARRARSLSAERYTLFFDLVSSGNTLYAIWIGLGTKNRVSFIEFVGWLCKKDHTHIREWFRQCTGRPKAAKPWLRAHPVAIPYDDPLTNEEIDLAYARGQAMNIEAPRLPDDPIIVEDDDESEEIEAESDEEEDKSGMESLKNIPQTLPYNPTVYGRPAVFDRKSDAKSTKKCRAIVTDFSVIKAIEEEHRKKKAARTEQPRATPESQAPTVVLQRPPTQQEPGPVGPLSVQARLEPWQPLPGPQVTAVLLHEESMQGVQVHGSMLDLLEKDDEVMEQRVMATLLPPVPQQPRAGRRGPCVFTGDLGIESDEPASTEPVHDQLLPAPGPDPLEIQPLTSPTTSQLSSSAPSCAQTPWPVVQPSQTPDDPTKQSRPPETAAPRQWPMPLRPIPMRPLRMQPIPFNHPVGPTPHQTPQVEITPYKPTWAQIGHIPYQPTPTGPATMLLRQWAPATMQTPPRAPTPMSPPEVPPVPRQRPRGAPTPTPPPQVPPVPRQRPRGAPTPTPPPQVLPTPMQLALRAPAGQQGPTKQILRQLLTGGVKKGRPSLKLQAALERQAAAGWQPSPGSGTSDKIVQAPIFYPPVLQPIQVMGQGGSPTAMAASAVTQAPTEYTRERRGVGPMPPTDIPPSKRAKIEAYTEPEMPHGGASHSPVVILENVGQGQQQTLECGGTAKQERDMLGLGDIAVSSPSSSETSNDE
What is the function of this protein?
May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.
What are the official names of this protein?
Epstein-Barr nuclear antigen 4, EBNA-4, EBV nuclear antigen 4, Epstein-Barr nuclear antigen 3B, EBNA-3B, EBV nuclear antigen 3B.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA-4 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: VATE_CLOPE
Sequence: MSNLNNLTSKILNDAEEKKKYILADAEAQKDKIISKKTNRAEADKEEIITKANIEAEVKKARIISNAKLSVRNDMLRAKQDVISKVFNEAIEKLQNLSNGDYKYYVISTLDSLELEGTEVIIINEKDKDIFSNEFLEALNKELESKGKKGSITLNMEGKFNGGFILDRNGIQINNTFEALINSLRGELEFEVNKVLFD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: RL32_CLOPE
Sequence: MGNPARKTFRAKRDSRRAQTFKASLPGIVECPQCHEMKMAHRVCKNCGHYKGKEVVSVEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ACDH1_MYCA9
Sequence: MASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVDWLLGQDEKPDLVFEATSAYVHKAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAPNVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVEVIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLLNEPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAKVS
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: KPYK_YARLI
Sequence: MIYTANSSPSTNLQWLSTLNTDDIPTKNYRKSSIIGTIGPNTNSAEMISKLRQAGLNIVRMNFSHGSYEYHQSVIENARESEQQFQGRPLAIALDTKGPEIRTGVTKDDKDWDVKAGHVMLFSTNPKYKDQCDDKIMYIDYTNIVKQIDIGKIIFVDDGVLSFKVLEKIDGETLKVETLNNGKISSRKGVNLPGTDVDLPALSEKDKADLKFGVEHGVDMIFASFVRTANDVQAIRDVLGEKGKGIQVISKIENQQGVNNFDEILKETDGVMVARGDLGIEIPAPQVFIAQKQLIAKCNLAGKPVICATQMLDSMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGTYPIESVKMMHETCLVAEKAIAYAPLFNEMRTLTVRPTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVTRNAQAARFSHLYRGVYPFIYHKARASNPAEWQHDVEERLKWGMDEAVALGILNKGDVVVAIQGWTGGLGHTNTLRVLECV
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: HSDHB_CLOSR
Sequence: MNFREKYGQWGIVLGATEGIGKASAFELAKRGMDVILVGRRKEALEELAKAIHEETGKEIRVLPQDLSEYDAAERLIEATKDLDMGVIEYVACLHAMGQYNKVDYAKYEQMYRVNIRTFSKLLHHYIGEFKERDRGAFITIGSLSGWTSLPFCAEYAAEKAYMMTVTEGVAYECANTNVDVMLLSAGSTITPTWLKNKPSDPKAVAAAMYPEDVIKDGFEQLGKKFTYLAGELNREKMKENNAMDRNDLIAKLGKMFDHMA
What is the function of this protein?
7beta-hydroxysteroid dehydrogenase that catalyzes the reduction of the 7-oxo group of 7-oxosteroids, such as 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate, 7-oxolithocholate, 7,12-dioxo-lithocholate and dehydrocholate, to the corresponding 7beta-hydroxysteroids.  Is also able to catalyze the reverse oxidation reactions.  Together with 7alpha-HSDH encoded in the adjacent gene, is likely involved in the epimerization of the hydroxy group at C-7 of primary bile acids through 7-keto bile acid intermediates.
What are the official names of this protein?
7beta-hydroxysteroid dehydrogenase, 7beta-HSDH, NADP-dependent 7beta-hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CAN2_RABIT
Sequence: QKLIRIRNPWGEVEWTGRWNDNCPNWNTVDPEVRERLAERHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYVIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELRGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKNGDFCVRVFSEKKADYQAVDDEIEADLEEADVSEDDIDDGFRRLFAQLAGEDAEISAFELQNILRRVLAKRQDIKTDGLSIETCKIMVDMLDSDGTGKLGLKEFYVLWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHEVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPDNTGMIQLDLISWLCFSVL
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  Proteolytically cleaves MYOC at 'Arg-226'.  Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.
What are the official names of this protein?
Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, M-calpain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: TDT_ONCMY
Sequence: MNHAGMLALVKKRKRPVEAGAQGQVEVKFKEVTLELVERKMGSSRRNFLTRLARSKGFRVEDVLSDDVTHVVAEDNQAEVLWAWLMGHGLRDVSRLALLDISWFTDSMREGRPVRVETRHSIQNTPTGTDCSPPTAVANVSQYACQRRTTTENHNNKIFTDVMEELAESSEFNESKGPCLAFRQAASVLKSLPSAVHCLKAIQGLPCLGEHTKAVMEEILTFGRSFKVEEIRCDERYQALKLFTSVFGVGPKTAEKWYRRGLRSLQEILTEPNIQLNRMQRAGFLYYSDISKAVSKAEAKAVGCIIEDTFHWIAPDAILALTGGFRRGKEYGHDVDFLLTMPEIGKDEGLLLHVIDRLKDQGILLYCDYQGSTFDVSKLPSCRFEDMDCFQKCFLILRLEQGQVEGERGLQRDPGDSRGWRAVRVDLVAPPVDRYAFALLGWTGSRFGRDLRTFAQKERQMLLDNHALYDKTKKLCLLATTEEDIFTHLGLEYVEPWQRNA
What is the function of this protein?
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.  One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
What are the official names of this protein?
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRPB_ECOLI
Sequence: MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYLSGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTDALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATPLFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYESINYYQYEEKLDNLFARSQVK
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
What are the official names of this protein?
2-methylisocitrate lyase, 2-MIC, MICL, (2R,3S)-2-methylisocitrate lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
Protein: RL35_DEIGD
Sequence: MPKMKTKKSMTRRVKVTATGKVMAFKSGKRHQNTGKSGDEIRGKGKGFVLAKSEWARMKLGLLAKGK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: YR135_MIMIV
Sequence: MKNKECCKCYNPCEKICVNYSTTDVAFERPNPCKPIPCKPTPIPCDPCHNTKDNLTGDIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHSHFNDPVVTDPMGFFGKYNPPNENISMSQNPSYSWQGAQEPNTGAYGNRPIIAHGMGFGGSTMINRLNLVVGGRTVFDNDWPVGWKYDDVKNYFRRVLVDINPVRDNTKASITSVALDALRIIAEQQIASGEPVDFLLNKATGNVPNVEKTTPDAVPLNLNDYEGVNSVVAFSSFYMGVNQLSDGNYIRKYAGNTYLNRNYVDENGRGIGKFSGLRVVSDAVVDRIIFKGNRAVGVNYIDREGIMHYVKVNKEVVVTSGAFYTPTILQRSGIGDFTYLSSIGVKNLVYNNPLVGTGLKNHYSPVTITRVHGEPSEVSRFLSNMAANPTNMGFKGLAELGFHRLDPNKPANANTVTYRKYQLMMTAGVGIPAEQQYLSGLSPSSNNLFTLIADDIRFAPEGYIKIGTPNIPRDVPKIFFNTFVTYTPTSAPADQQWPIAQKTLAPLISALLGYDIIYQTLMSMNQTARDSGFQVSLEMVYPLNDLIYKLHNGLATYGANWWHYFVPTLVGDDTPAGREFADTLSKLSYYPRVGAHLDSHQGCSCSIGRTVDSNLKVIGTQNVRVADLSAAAFPPGGNTWATASMIGARAVDLILGFPYLRDLPVNDVPILNVN
What are the official names of this protein?
Putative GMC-type oxidoreductase R135.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein.
Protein: IGSF1_MOUSE
Sequence: MMLRTFTLLLLCIWLNPGMTSLAVESQPELWIESNYPQAPWENITLWCKSPSRVSSKFLLLKDNSQMTWIRPPYKTFQVSFFIGALTESNTGLYRCCYWKEKGWSKPSKILELEAPGQLPKPIFWIQAETPPLPGCNVNIFCHGWLQDLVFMLFKEGYTEPVDYQVPTGTMAIFSIDNLAPENEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPILAPGESLSLRCQGPIYGMTFALMRLEDLKKSFYHKKPIKNEAYFYFQDLKIQDTGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLVQPSPVIQMGQNVSLRCGGLMDGVGLALYKKGEEKPLQFLDASSNTGNNSFFLKNVTYRDAGIYSCHYYLTWKTSIKMATYNTVELMVVAWPSSVFKVGKTITLQCRVSHPVLEFSLEWEERTTFQKFSVDGDFLITDIEGQGTGTYSCSYRIEAHPNTWSHRSKPLKLVGPAGFLTWNSILNEAVRVSLTMQLASLLLLVVWIRWKCRRLRLREAWLLGTAQGVAMLFILMALLCCGLCNGALTEEIEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTHSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASLPIRGQELQIRCKGWLEGLGFALYKKGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEMQPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGSRVTFNCSTSHEHMSFILYKDGNEIASSDLAWGNPGGSTAHFLIISVGIGDGGNYSCRYYDFSIWSEPSNPVELVVTEFYPKPTLLAQPGPVVLPGKNVTLRCQGIFQGMRFALLQEGTHTPLQFQSTSGTSADFLLHTVGAQDFGNYSCVYYETTMSNRGSSLSTPLMIWVTDTFPRPWLSAEPSSVVTMGQNVTLWCQGPVRGVGYILHKEGEATSMQLWGSTSNEGAFPIINISGASIGRYSCCYHPDWMSPIKIQPSNTLELIVTGLLPKPSLLVQPGPMVAPGENVTLQCQGELPDSTFVLLKEGTRQPLEQQRPSGYRADFWMPVVRDQDSGVYSCVYYLDSAPLVASNHSNSLEIWVTDKPPKPSLSAWPSTIFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVIDNLEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPVAQECTVGNIVRSTLIVVVVVALGIVLAVEWKKWPRLRTRGSETDGRDQTVVLEECNQEGEPGTTTNSPSSASQEVSVELTVPI
What is the function of this protein?
Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor.  Antagonizes activin A signaling in the presence or absence of inhibin B.  Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 1, IgSF1, Inhibin-binding protein, InhBP.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Secreted. SUBCELLULAR LOCATION: [Isoform 5]: Secreted.
Protein: Y733_LACAC
Sequence: MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKSGGPDPDGNPALRMVIDKARSNNMPKDNIQRAIKKAEGGSDEHYDEITYEGYAPGGVAVFVEALTDNKNRTASDVRVAFTRNGGSLGATGSVAYMFDRKGYIVIDRSTTDADEDQVLLDVMDAGGDDLQTSDDAYEIYTDPKQFAEVRDALIKAGYKLADAELTMIPQNTTPVPADKKEQFEHLVEALEDSDDVQNVYTAAADED
What are the official names of this protein?
Probable transcriptional regulatory protein LBA0733.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB_MYCTU
Sequence: MTWPLPDRLSINSLSGTPAVDLSSFTDFLRRQAPELLPASISGGAPLAGGDAQLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSGADTFGSDGGEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The M. tuberculosis proteasome is able to cleave oligopeptides not only after hydrophobic but also after basic, acidic and small neutral residues (PubMed:16468985).  In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin-like protein (Pup).  Among the identified substrates of the M. tuberculosis proteasome are the pupylated FabD, PanB and Mpa proteins (PubMed:17082771).  One function of the proteasome is to contribute to M. tuberculosis ability to resist killing by host macrophages, since the core proteasome is essential for persistence of the pathogen during the chronic phase of infection in mice (PubMed:18059281).  Likely functions to recycle amino acids under nutrient starvation, thereby enabling the cell to maintain basal metabolic activities (PubMed:20711362) (By similarity).  The mechanism of protection against bactericidal chemistries of the host's immune response probably involves the degradation of proteins that are irreversibly oxidized, nitrated, or nitrosated.  A proteolysis-independent activity of the proteasome core is required for optimal growth of M. tuberculosis in mouse lungs and for RNI resistance; in contrast, long-term survival of M. tuberculosis in stationary phase and during starvation in vitro and in the chronic phase of mouse infection required a proteolytically active proteasome (PubMed:20711362).
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTX31_ACTPL
Sequence: MSTWSSMLADLKKRAEEAKRQVKKGYDVTKNGLQYGVSQAKLQALAAGKAVQKYGNKLVLVIPKEYDGSVGNGFFDLVKAAEELGIQVKYVNRNELEVAHKSLGTADQFLGLTERGLTLFAPQLDQFLQKHSKISNVVGSSTGDAVSKLAKSQTIISGIQSVLGTVLAGINLNEAIISGGSELELAEAGVSLASELVSNIAKGTTTIDAFTTQIQNFGKLAENAKGLGGVGRQLQNISGSALSKTGLGLDIISSLLSGVTRSFALRNKNASTSTKVAAGFELSNQVIGGITKAVSSYILAQRLRAGLSTTGPAAALIASSISLAISPLAFLRVADNFNRSKEIGEFAERFKKLGYDGDKLLSEFYHEAGTIDASITTISTALSAIAAGTAAASAGALVGAPITLLVTGITGLISGILEFSKQPMLDHVASKIGNKIDEWEKKYGKNYFENGYDARHKAFLEDSFSLLSSFNKQYETERAVLITQQRWDEYIGELAGITGKGDKLSSGKAYVDYFQEGKLLEKKPDDFSKVVFDPTKGEIDISNSQTSTLLKFVTPLLTPGTESRERTQTGKYEYITKLVVKGKDKWVVNGVKDKGAVYDYTNLIQHAHISSSVARGEEYREVRLVSHLGNGNDKVFLAAGSAEIHAGEGHDVVYYDKTDTGLLVIDGTKATEQGRYSVTRELSGATKILREVIKNQKYAVGKREETLEYRDYELTQSGNSNLKAHDELHSVEEIGSNQRDEFKGSKFRDIFHGADGDDLLNGNDGDDILYGDKGNDELRGDNGNDQLYGGEGDDKLLGGNGNNYLSGGDGNDELQVLGNGFNVLRGGKGDDKLYGSSGSDLLDGGEGNDYLEGGDGSDFYVYRSTSGNHTIYDQGKASDSDKLYLSDLSFDNILVKRVNDNLEFRSNNNSNSGVLTIKDWFKGGNSYNHKIEQIVDKNGRKLTAGNLGNNFHDTQQASSLLKNVTQEQNESNLSSLKTELGKIITNAGNFGVAKQGNTGINTAALNNEVNKIISSANTFATSQLGGSGMGTLPSTNVNSMMLGNLARAA
What is the function of this protein?
Does not have hemolytic activity but shows a strong cytotoxicity towards alveolar macrophages and neutrophils.
What are the official names of this protein?
RTX-III toxin determinant A from serotype 2, APX-IIIA, Cytolysin IIIA, CLY-IIIA.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: RS19_CHLAD
Sequence: MSRSSKKGPYVDIKLLDKIEAMNKANEKRAIRTWSRDSTIFPQMIGHTILVHDGRRHVPVYITENMVGHKLGEFAPTRFFRGHGGKKADKRGKVK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL21_ECO8A
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.