PharMolix/UniProtQA huggingface dataset:
Protein: Y3400_CLOD6
Sequence: MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELCYQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMTRRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDNPNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKISEEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVVKKHRDSMLR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CD630_34000.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CYSA_MESVI
Sequence: MSILIDNISKKFGNFQALNHINLEIKSGSIIALLGPSGSGKSTLLRIIAGLDTPDEGTIWISGKNASGYSIQSRNIGFVFQNYALFKNMTVYDNIAFGLELRRISFNDISRKVNKLLELVQLQNLGHRYPAQLSGGQRQRIALARALAIEPKVLLLDEPFGALDARVRKNLRAWLRDLHNKFSITTIIVTHDQQEAMEIADEIVVFNSGRIEQIGKPQDIYDQPATPFVFSLLGYVNKISFDNEIANFLLSSFPEKQSVLMQEKQFYIRPHQIVISKQSNESNYSAKIENLLYIGNWIHLDIYVASFNVNLKVHVSPKEFDNLQLKSFQENIYVSLRSKGKEPIRFLE
What is the function of this protein?
Part of the ABC transporter complex involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SEY1_MALGO
Sequence: MGLDVDSVPIAEAAAPSSMAATEPPADKIAQLDRDASNVAPMNTDSSRETMPTSPRALEPAQVTPLSSDVAYEGLVQGKDPSDDSIIAATPLQRTFSTVAPTMTTQPNRLQLIDEDQQFHGAEFNDHLKQWGLSDAGFGYDICAVLGSQSTGKSTLLNRLFGTNFDVMDERARQQTTKGIWLCRGMDRNVLVMDVEGTDGRERGEDQDFERKSALFSLATAECLIVNMWENQVGLFQGANMALLKTVLDVNLSLFQAGRARAGSAKEKTLLLFVIRDFIGTTPLANLEATIRTDLQRIWASLTKPESLVHAELGDFFDLGFATLPHKVLQAKEFDADILKLQRRFIDRGDESYVFKTEYHKRIPIDGLPHYLEGVWEQIVQNKDLDLPTQQELLAQFRCDEIATTASLAFSSAMSALRAELDAGHVLESLGNDMARHRSEALAMFDKDASRYHQVVYARKREDLLVKLNAALLPFFLCQLKNLHNELTDQCKRVIQEGTKQPAYNFGLLVEEGITKAMRAFDDETARLVLPETDWKVDDERAQLLDELHTLARTLRANETRKLSIQLEKDMRRELADPVELALSQPDISMWNNVLSAFHRVNEQVANMYRTRAASLNTTPDEDTTAVAQLQQASWRLLLEKVHEQTSETVLASRLRGYFEDRFRYDAGGVPRVWKPSDDIDDIFVKSRDATLALIPLYATIQPDDPSLQMSVVSLVGAPEESLETPSYDEARHVLSERKCAEIGQRFRREADAAYIEAKRGTVSSMSQVPIWMYGVLVVLGWNEAMAVLRNPVYFTLLCMVLATAYVIWRLNLGTPVLALASGMTRELRAFGEEQLRTYLDGTPPSANRAREYRVPSGSTAHVSEKTPHRPLTTSGAAEADTVEDSHPRLPASF
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: ECTB_WOLSU
Sequence: MRIFEQLESQVRSYIRSFPVIFERSKGAYLYDEQGKAYIDFFAGAGTLNYGHNHPKIIEAMIAYLQNDGILHGLDKATSAKKAFLQTLSETILEPRHMDYKVQFTGPTGTNAIESALKLARMVKGRSNVIAFTNAFHGLTMGSMAVTGNAFYRDEAFVNRANVSFMPFDGYFGEEVDTSLYLRRFLEDGSSGVDLPAAIILETIQAEGGVNVARDEWLRSVEKVCRDFDILLIVDEIQVGNGRTGRFFSFEESGIRPDIITLSKSIGGGLPLALVLLRPELDQWKPGEHTGTFRGNNLAFVAAKEALEYWSDSVLGEWVKHNSAILKEGLEALVQAFPELGMSARGRGLIYGLEIPLSGMAKEVSANCFQKGLVIELAGASDTVLKFLPPLIIEEETLREGLGIIKEAIGEVLREREARMGEVFGDR
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: ATNJ_EMENI
Sequence: MSTFPAEPRSDIVNGHVESDFNYQTGTWSEPVFVQDHYLKVHGLAPGLNYGQQVFEGMKAYRDPNGQIQIFRPTDHALRMQRSCDAVSIPSIPESLFWASVNLAVAKNSEFVPPHASEAAMYIRPLAFGSGGWMPVAAGPQYKFVVYALPFCAYHGTLPVDAVVLEELDRAAPLGVGNVKVGGNYAPVLKWSDKARKEGFGITLHLDSKTRGEIDEFSTSGFVGIKYTESGGEKGYTLVVPNSQCIIKSVTSTSVVEVARSLGWRVEVRPIPYDELEFFDEVLAVGTAAMITSIRSITHRSKDQVFRYKTSDEPGSACEKLSRHLKGIQKGDEKDTFGWLKRVEEVTV
What is the function of this protein?
Aminotransferase; part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino-dodecanol (2adol) (PubMed:23248299, PubMed:27310134, PubMed:26563584).  The core structure of aspercryptins is as follows: Ser/Ala-Thr-Ile/Val-2aoa-Asn-2adol (PubMed:27310134).  The first step of aspercryptin biosynthesis is the generation of the fatty acid precursors, octanoic and dodecanoic acids, by the FAS subunits atnF and atnM (PubMed:27310134, PubMed:26563584).  The fatty acid precursors are likely transformed into the corresponding alpha-amino fatty acids in three steps (PubMed:27310134, PubMed:26563584).  First, they are hydroxylated by the cytochrome P450 monooxygenase atnE, then oxidized to the corresponding alpha-keto acids by the NAD(P)-dependent oxidoreductase atnD, and finally converted to the alpha-amino fatty acids by the PLP-dependent aminotransferases atnH or atnJ (PubMed:27310134, PubMed:26563584).  the alpha-amino fatty acids, 2-amino-octanoic and 2-amino-dodecanoic acids, are recognized, activated, and covalently tethered to the NRPS atnA by its fourth and sixth adenylation domains (PubMed:27310134).  The second module of atnA is the Thr module and contains an epimerase (E) domain responsible for the epimerization of Thr to D-allo-Thr (PubMed:26563584).  Additionally, despite atnA having only one epimerase domain, the first amino acid of aspercryptin A1 is D-Ser, suggesting that serine is either loaded directly as D-Ser on the first module or that the epimerase domain in the threonine module epimerizes both L-Ser and L-Thr (PubMed:27310134).  After condensation of the hexapeptide of aspercryptin, the C-terminal reductase (TE) domain might be involved in the reductive release and production of the aldehyde hexapeptide (PubMed:26563584).  Further reduction would generate aspercryptins (PubMed:27310134, PubMed:26563584).  The variety of aspercryptins produced reflects the flexibiliy of the atnA NRPS, allowing incorporation of alanine instead of serine, valine for isoleucine, and a C10 fatty amino alcohol instead of the C12 version (PubMed:27310134).  AtnB seems to be involved in the selectivity for Ile versus Val by the third module (PubMed:26563584).  Moreover, type B, C and D aspercryptins have an additional N-terminal cichorine, acetyl and propionyl group respectively (PubMed:27310134).
What are the official names of this protein?
Aminotransferase atnJ, Aspercryptin biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: UREF_PSEAE
Sequence: MNSIWARLRLASSQLPIGGYSYSQGLEAALDNGWVRDAESARTWLVDQLQLNLARFEAPLLAGLLRAALIGDWAACDAASERHRASRETRELAQESRQMGFSLHQLLEALPELDAPGRAWLARQDPPNLAAAWAMAARAWRLDAEEALSAWFWSWLENQLAVLMKTLPLGQLAAQKLASSLLPELDRACAEALRRPAVEGSAAFGLALASMTHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SYNS3
Sequence: MMTASQRYDTKIHRRVTRTVMVGDVPIGSEHPIAVQSMINEDTLDIDGSVAGILRLADAGCEIVRVTTPSIGHAKAMGKIRSALRAQGCKIPLVADVHHNGTRIALEVAKHVDKVRINPGLFVFDKPDPDRQEFSKEEFDAIGDRIKETFAPLVQVLKEQNKALRIGVNHGSLAERMLFTYGDTPQGMVESAMEFVRICDSLDFHNIVISMKASRAPVMLAAYRLMADTMDREGFNYPLHLGVTEAGDGDYGRIKSTAGIATLLAEGLGDTLRVSLTEAPEKEIPVCFSILQALGIRKTMVEYVACPSCGRTLFNLEEVLHQVRNATCHLTGLDIAVMGCIVNGPGEMADADYGYVGKGPGVIALYRNRDEIRKVPESEGVEALVQLIKDDGRWVEPD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL7_BUCA5
Sequence: MSITKEQILEAISEMSVMNVVDLITAMEEKFGVSASMSINSNNHNEKDLREEKTEFDIFLKVIGPNKVSVIKTVRSATGLGLKEAKDLVESAPTVLKENISKEDAESLKKTLEDVGAEIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PLB2_ASPFC
Sequence: MYKNRVELTTTAPVNRALPNAPDGYTPQGETCPSKRPSIRNATALSSAETSWLKARRNNTKDALKAFLSRVDLGSFNGSDYIANHSANASALPNIGIAVSGGGYRALMNGGGALQAFDNRTTNSTHSGQLGGILQSATYLSGLSGGSWLVGSIYMNNFSDVSSLQDNGSVWQFQDSIFSGPTQSTTWDIGTVEYYSQLLGAVDGKSNAGYEVSITDYWGRSLSYQLINASEGGVGYTWSSIALSKDFQAGTMPMPLVIADGRAPGEILVPANTTVFEFNPWEFGSWDKSLSAFVSLEFLGSNFSKGTLATGEKCVRGFDNAGFIMGTSSSLFNQAFLQMNNTDAPSVVKDAISAILGKIGSENNDIAVYKPNPFYRYASQSKYTSSPSLTLVDGGEDLQNIPLDPLLQPQRHVDVILAVDSSADTTTRWPNGTSLVATYERNVDSSQRNSSLPFPSVPDQNTFVNLGLNNRPTFFGCNSSNATGAPLVVYIPNAPYIYPSNVSTFDLQYNTSERNAIIENGYDVATLGNGTVDSNWPACLACAILSRSFERTNTTVPKTCSTCFKTYCWNGTINATTPGDYYPTLKLH
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Lysophospholipase 2, Phospholipase B 2.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
Protein: MLTC_SHIF8
Sequence: MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQNTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: THIE_ECOL5
Sequence: MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLSAIRAAGLRLGVSTHDDMEIDVALAERPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: YKW2_YEAST
Sequence: MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSCSSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNPLSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYSTLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKVLRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEVFHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGLNEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENYSSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNLNGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETYFELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQRNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFSIIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDILGSPSAFFDTAISGWSNFEDFFSR
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein YKL222C.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHLB_PICMA
Sequence: RRLLKDLDIRINQIIPEGGSVEDSKNLPKARFNLIPYREVGLMTAMYLNKEFGMPYVSTTPMGAVDMAECIRQIKKYIDTLAAPILSSKRVDYESYIDGQTRFV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex (By similarity).
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURT_XANOP
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPAALRVLIASERPHVIVPEIEAIHTETLVALEREQGQKVIPAARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAADYREAIAAVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWEYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSYCDPIGHWQQDGDYRESWQPQPMSAAALRRSQEIAKAITDDLGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAEDGGVIGQSGPSASCALLAHGNGVPVFDNVADALRDPDTALRLFGKPRVDGHRRVGVTLARADSIDAAREKARVAAAALGIQLTA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ISPH_KOSOT
Sequence: MKIVLAESLGFCYGVNRAVEATKRLLKEKRDARVIGDIVHNEIVMKKLKDMGLKVYPDLSSIDFSDTAENSVAIIRAHGASPDVEDFLKRRFGYVVDLTCPIVYNVFSLAKDLEKKGYFIVIFGKKDHAEVKALCGRLNDYLIVEPGYDFETIKAFLREKKPKKVALISQTTMNSESFEKLAEKLLKLEGIEVSVNNTICNVTINREKMAIHLAQTCDAVVVVGGKRSSNTGKLAKIVESHGKRAFHVQNPEQLPDLSIYRKVGIISGTSTPKEQILKILDYIKFTYEGEVIRNGGEV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: B4GT4_CRIGR
Sequence: MGCNPPYLLPYRLRLLLFFTLCLTVVGWVTSNYFVDPIQVIPKAKVFMASFYKVIPLGKEETLVHDATMEKVELGNCPSVSPNLRGQSKLIFEPDLTLEEVQAKNPKVSGGRYHPEECKAVQRVAVLIPHRNREKHLTYLLEHLHPFLQRQQLDYGIYIIHQTGSKKFNRAKLLNVGYLEALKEQNWDCFIFHDVDLVPENDFNLYTCGDQPKHLVVGRNSTGYRLRYSKYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELHKMKISRPNPDVGKYTMIFHTRDKGNEVNVDRMKLLHQMSRVWKTDGLSSCSYRLLSVEHNPLYTNITVDFWTGV
What is the function of this protein?
Galactose (Gal) transferase involved in the biosynthesis of glycoproteins, proteoglycans, and glycosyphingolipids.  Catalyzes the transfer of Gal residue via a beta1->4 linkage from UDP-Gal to the non-reducing terminal N-acetyl glucosamine 6-O-sulfate (6-O-sulfoGlcNAc) in the linearly growing chain of both N- and O-linked keratan sulfate proteoglycans.  Cooperates with B3GNT7 N-acetyl glucosamine transferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer.
What are the official names of this protein?
Beta-1,4-galactosyltransferase 4, Beta-1,4-GalTase 4, Beta4Gal-T4, b4Gal-T4, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, Lactotriaosylceramide beta-1,4-galactosyltransferase, N-acetyllactosamine synthase, Nal synthase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 7 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.
Protein: FADS2_RAT
Sequence: MGKGGNQGEGSTELQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIRRRDWVDLAWAISYYARFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHIVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIVSSLKKSGELWLDAYLHK
What is the function of this protein?
Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain.  Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (PubMed:10049752, PubMed:22216341, PubMed:11988075, PubMed:14563830, PubMed:24070791).  Subsequently, in the biosynthetic pathway of HUFA n-3 series, it desaturates tetracosapentaenoate (24:5n-3) to tetracosahexaenoate (24:6n-3), which is then converted to docosahexaenoate (DHA)(22:6n-3), an important lipid for nervous system function (PubMed:11988075).  It can also desaturate (11E)-octadecenoate (trans-vaccenoate) at carbon 6 generating (6Z,11E)-octadecadienoate (PubMed:24070791).  In addition to Delta-6 activity, this enzyme exhibits Delta-8 activity with slight biases toward n-3 fatty acyl-CoA substrates (By similarity).
What are the official names of this protein?
Acyl-CoA 6-desaturase, Delta(6) fatty acid desaturase, D6D, Delta(6) desaturase, Delta-6 desaturase, Fatty acid desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: YT22_CAEEL
Sequence: MSSQQQESEASGYNTSASSEFGSLEDSHQFVSPVTRHASKRRAVENVDHLDELMKSSMVLSPEKRLRLNTSNDSNLVRNTARSPDSSMNGRPQTRRSTSSDIEISPRVRAMRSTSGSSMDLVRTVSSFCTDSISPKFFTNHGSTTRKRTENGSIYSRHRLGATFSPLVAGAKRKMATPSQSLKRQEKQSPLESRHGGLRSRGTPQRKLLLCDRLKVLN
What are the official names of this protein?
Uncharacterized protein B0304.2.
Protein: RIMO_DESAP
Sequence: MNSPWKAEASRIALVSLGCDKNRVDGEVMLGLLERAGYQITAELEADIILVNTCAFIQDAKQESIEAILETARYRGNGRCRVLLATGCLAQRYPDELLRDIPELDGVVGTGEVGRVVDIVRRAATGERVREVGPPGFLGREVLPRVPSGSPFTAYLKISEGCDNRCLYCVIPQLRGPYRSREASVLVREARALAARGAREIVLVAQDTTRYGSDLKERTSLTDLVSRLAALEGVAWIRLLYCYPSGITFELVELMAREPRLCRYLDIPLQHASDRVLRRMGRSTMSYDLRKLILFLRSAIPGLTIRSTFMVGFPGETEADFEELLGFLKAMKLDRAGFFAYSREEGTPAARMPDQVPPEVKRERLERAAAVQREVSRALNRARVGSEVTVLVEGRKGEQYYGRSEADAPDIDGRVFLSAASDLEPGTFVRARITGAGPYDLRARVLSTLP
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEAHC_ARATH
Sequence: MRNSFPPSDGGRSATDRRQQSSHSSSTNRYNSRSAQSSPPLNHRPTWNQQHSQYPNSNFPPNYRRDRNPSSGYSPPVTRARPNFIVQLLHPAAANSDTKLCFSTKKQEIESLALLCEIPEESIHVPQFGCIAGSFSFRQWVDARSAVVALWDYRLQGKHEFVPELIPNVIVPSDMNELKDRLRDLFSSHILSLMENGEGVKKVRLEIEEKSRQVVSFSSKRGLKFEVFEKKKAIEAERDLVVNRLEEFNNAMKSILRYLIGQDGYEFDLDDEEEGDVAVFCLEGAYDWRRIHCLIRRECRRLEDGLPIYAYRRQILKKIHREQIMVLIGETGSGKSTQLVQFLADSGVAASESIVCTQPRKIAAMTLADRVREESSGCYEENTVSCTPTFSSTEEISSKVVYMTDNCLLQHYMKDRSLSGISCVIIDEAHERSLNTDLLLALLKKLLSRRIDLRLVIMSATADAKQLSQYFFSCGILLVNGRNFPVEIVYSPSDTEENSVVGGIASYVGDVVKMAVEIHKTEKEGTILAFLTSQAEVEWACERFITPSAIALPLHGKLSFEEQFRVFQNHPGRRKVIFATNIAETSLTIPGVKYVIDSGMVKESKYEPRTGMSILKVCRVSQSSARQRAGRAGRTEPGRCYRLYSKNDFDSMNLNQEPEIRRVHLGVALLRMLALGVNNIAEFNFVDAPVPEAIAMAVQNLVQLGAVVEKNGVHELTQEGHCLVKLGLEPKLGKLILGCFRHRMGKEGIVLAAVMANASSIFCRVGNFDDKMKADRLKVQFCNQNGDLFTLLSVYKEWASLPRERRNKWCWENSLNAKSMRRCEDTVKELEICIERELTLVSPSYWVWNPNEGTKHDKHLKMVILASLAENVAMYTGYNQLGYEVALTGQQVQLHPSCSLLAFGQKPSWVVFGELLSIVDQYLVCVTACDFEALYMLDPPPPFDVSQMDERRLRIKKVVGCSSTVLKRFCGKSNRSLLSIVSRARSLCSDERIGIQVDVDQNEIRLYAPPLDMEKVSALVNDALECEKKWMHNECLEKYLYHGRGQVPIALFGSGAQIKHLEVDQRFLTVDVLYYGDDVVDDRELLTFLEKKIDGSICSIYKFAANKQDCDEKEKWGRITFLTPESAMKATEIQKFYFKGSVLKLFPSLSTGGGIFKMPYFSSVTAKIRWPRRESSGRGCLKCPSGDIHRILGDISSLEIGTNYVHIQRDQQSNDSILISGLGDLSEAEVLDVLEFRTQRRDLNFFIFRKKYSVQCPSPTACEEELHKRIFARMSAKNPEPNCVQVQVFEPKEDNYFMRALIKFDGRLHFEAAKALQELNGEVLPGCLPWQKIKCEQLFQSSIICSASIYNTVKRQLNVLLARFERQKGGECCLEPTHNGAYRVKITAYATRPVAEMRRELEELLRGRPINHPGFTRRVLQHLMSRDGINLMRKIQQETETYILLDRHNLTVRICGTSEKIAKAEQELIQALMDYHESKQLEIHLRGPEIRPDLMKEVVKRFGPELQGIKEKVHGVDLKLNTRYHVIQVHGSKEMRQEVQKMVNELAREKSALGEKPDEIEVECPICLSEVDDGYSLEGCSHLFCKACLLEQFEASMRNFDAFPILCSHIDCGAPIVLADMRALLSQEKLDELFSASLSSFVTSSDGKFRFCSTPDCPSVYRVAGPQESGEPFICGACHSEICTRCHLEYHPLITCERYKKFKENPDLSLKDWAKGKNVKECPICKSTIEKTDGCNHMKCRCGKHICWTCLDVFTQEEPCYAHLRTIHGGIGLVE
What are the official names of this protein?
ATP-dependent RNA helicase DEAH12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NFI_XANAC
Sequence: MQTNDPVFAGWDGSVIQARQLQRQLARRVVLDDAVSATPQLLAGFDVGFEDDGQTTRAAAVLLDAQTLLPLETHIARVPTSMPYVPGLLSFRELPALLQALALLSRTPDLVFIDGQGIAHPRKLGIAAHFGVVTGLPCIGIAKQRLAGSFAEPGPERGDHTPILLGGSQIGWALRSKPRCNPLIVSPGHRVSMQGALDWTLRTLRAYRLPEPTRLADRLASRRGEVTVPAGYSGHLL
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_THEP1
Sequence: MNVAILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVVEKRVFHEKVLGIVEGGDTRSQSVRSALEFLEKFSPSYVLVHDSARPFLRKKHVSEVLRRARETGAATLALKNSDALVRVENDRMEYIPRKGVYRILTPQAFSYEILKKAHENGGEWADDTEPVQKLGVKIALVEGDPLCFKVTFKEDLELARIIAREWERIP
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.