PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_PINCO
Sequence: MPVGVPKVPFRAPGDEDATWVDLYNRLYRERLLFLAQDINNEIANQLMGLMVYLSAEDANKEIFSFINCPGGSVIPGVGLYRMMQAIVPDVNTICMGVAASMGSFILIGGEMPKRIALPHARVMIHQPASSYYDGSAADFHNESKHVTLVREYITECYIERTGQPEEVIQRDLNRDVFMSATEAQAYGIVDVVAEDPLIFNRFLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: METK2_SUASA
Sequence: MESFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTKANIDYEKIVRDTCRSIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEDVGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYNNDNGAMVPIRVHTVLISTQHDETVTNEQIAADLKEHVIKPVIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRAIVQVSYAIGVPEPLSVFVDTYGTGKIPDKDILKIVKENFDFRPGMISINLDLKRGGNARFQKTAAYGHFGRDDPDFTWETVKPLKWEKVPASS
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEY_ENTCL
Sequence: MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFVISDWNMPNMDGLELLKTIRADAGMASMPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLGKIFEKLGM
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity).
What are the official names of this protein?
Chemotaxis protein CheY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFHX2_HUMAN
Sequence: MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQGFSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCLLCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKFLLDMEGAEAGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPGKAPVTPLAEPPTPEKDAQNKTEQLASEETENKTGPSRDSANQTTVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVATTVEMTFTTKVLSAPTLSPLDNGQEPPTHGPEPTPSRDQAAEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTSTLLAL
What is the function of this protein?
Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli.
What are the official names of this protein?
Zinc finger homeobox protein 2, Zinc finger homeodomain protein 2, ZFH-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PQQB_KLEP7
Sequence: MFIKVLGSAAGGGFPQWNCNCANCQGLRDGTIQAAPRTQSSIIVSDNGKEWVLCNASPDISQQIAHTPELNKAGVLRGTHIGGIILTDSQIDHTTGLLSLREGCPHQVWCTPEVHEDLSTGFPVFTMLRHWNGGLVHHPIAPQQPFTVDACPDLQFTAVPIASNAPPYSPYRDRPLPGHNVALFIENRRNGQTLFYAPGLGEPDEALLPWLQKADCLLIDGTVWQDDELQAAGVGRNTGRDMGHLALGDEHGMMALLASLPAKRKILIHINNTNPILNEQSPQRQALTQQGIEVSWDGMAITLQDTAC
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: UB2D4_XENLA
Sequence: MALKRIQKELMDLQRDPPAQCSAGPVGEDLFHWQATIMGPNDSPFQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWTQKYAM
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Regulates pronephros development, possibly by promoting ubiquitination and thus inactivation or degradation of map3k10/mlk2.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D4, E2 ubiquitin-conjugating enzyme D4, Ubiquitin carrier protein D4, Ubiquitin-protein ligase D4.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: UN932_ARATH
Sequence: MNVRDEGKTTAEKHGGGEENKSPENKWRFNSPLAQVSLMGFVCFCCPGMFNALSGMGGGGQVDPTAANNANTAVYTAFTVFGLLGGGFYNVLGPRLTLAAGCSTYVLYAGSFLYYNHHHHQAFAIVAGALLGCGAGLLWAGEGAVMTSYPPPHRKGTYIALFWSIFNLGGVIGGLIPFILNYQRSSAASVNDSTYIAFMCFMFAGVLLSFGILPATSVIRNDGSRCSAVKYSRPSTEAAAVLRLFLDRKMLLIVPAAWASNFFYSYQFNNVNGLLFNLRTRGFNNVFYWGAQMAGSIAIGYVMDFSFKSRRARGFTGISLVAVIGTIIWAGGLANQHGYSLDKLPEKKLDFKDSGIEFAGPFVLYMSYGLLDAMYQSMVYWLIGALADDSQTLSRYSGFYKGVQSAGAAVAWQVDTRKVPLMSQLIVNWSLTTVSYPLLVLLVYFYVKNDNDDDSNDKV
What are the official names of this protein?
UNC93-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NGCE_STRCO
Sequence: MTIRAGSLDRRTLLRGAIATAAMGSFAVACSSPSSEDKESDSGPKGEKSANNPFGAAANSTVEAAIFDGGYGTDYVDYANQVLGSQVKGLKVQVKPVVDIAPQLQPRFVGGNPPDLIDNSGEDQIGFLGILDQLEELDDLFEASTYEGKKIADIVYPGVKDPGTFKDKFVALNYVMTVYGVWYSKTLFEENGWTPPKTWDEALDLGQEAKKKGKYLFVHGKEAATYYRTLLIDSAIKEGGDEVRLALENLEKGCWSHPAVQGVIKVMETMVKQKMFVPGGSGTQFQKAQAIWSNDQKALLYPSGGWIENEMKKATKADFQMTGIPSMTLTDKPALPYEALRAAAGEPFIVPKQGKNPAGGKEVLRAMLSEKAAANFSKTKLAPTIVKGTVPADGYGSTALVSQTKMLEAAGTNIFNYMFVETYGLNTDQLVPWNSFLAGDLDGKGLTSALQKISDKVREDDSVDKVKVS
What is the function of this protein?
Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake.  Binds (GlcNAc)2.  Can also bind GlcNAc.
What are the official names of this protein?
Diacetylchitobiose binding protein NgcE.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: SYV_STRPQ
Sequence: MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQTLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMQKLVK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_PECAS
Sequence: MSRPRRRGRDVHGVLLLDKPQGVSSNDVLQKVKRIFNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGNVIEERAIGFSATDLELALESFRGTTQQVPSMYSALKYQGRKLYEYARQGLTVPREAREITVYELQFIRWEGDELELEIHCSKGTYIRTIIDDLGEQLGCGAHVIYLRRLQVAIYPTERMVTLEQLAALAEQAQTQEHSLSLSLDSLLMPMESPVIDFPEVNLPPVVAGYLKLGQAVQAANAPLNGMVRITEGDAHKFIGMGEIDGDGRVAPRRLVVEFPV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: HRCA_STRGC
Sequence: MVTERQNEILNLIIDIFTKTHEPVGSKALQDSINSSSATIRNDMAALEKQGLLEKAHTSSGRKPSVAGFQYFVKHSLSFDRLAENELYEVIKAFDHEFFNLEDILQQAADLLAKLSGCTVVALDVEPSRQRLTAFDIVVLSQHTALAVFTLDESNTITSQFMIPRNFLREDLDRLKALVQERFLGQTVLDIHYKIRTEIPQIIQRYFTTTDNVIHLFEHIFGDIFKENVIVSGKVGLLNFSDLKAYQFFDDSQKVAFEIRDSLAEDQMQSVRVADSRESCLSDLTIISSKFLIPYRGFGILAVIGPVNLDYQRVVSQVNVINRVLTMKLTDFYRYLSSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GYRB_CHIJA
Sequence: DKNTYKVSGGLHGVGVSCVNALSTVLHVTVHREGKIFEQEYHRGVPQYAVREIGATTDTGTTTHFKPDGEIFTETSYNREILAGRLRELAYLNRKIRITLTDEREKDEQGNVLSEPFYSEGGIMEFVQMLDRNGRRNSLLPAPIFIEAHDAPSNVAVEVSLQYNDSFSENIFSYVNNINTIEGGTHVAGFRRAITRVFKTYGDRNKLFEKSKIEVTGDDFREGLSAIVSVKVPEPQFEGQTKTKLGNSDVMGVVDSAVADVLNAYLEEHPKEARTVINKVVLAAQAREAARKARQLVQRKSVLTGSGLPGKLADCSENDPEKCELYLVEGDSAGGTAKQGRNRAFQAILPLRGKILNVEKAMEHKIYENEEIKNIFTALGVTIGTEEDDKALNLSKLRYHKLIIMTDADVDGSHIATLILTFVFRYMKALVEQGYVYIAQPPLYLVKKGKEQIYAWTEEQRKAAVATLAGGKEDSVTIQRY
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_MYCBO
Sequence: MAGIASTVAVMGAGAWGTALAKVLADAGGEVTLWARRAEVADQINTTRYNPDYLPGALLPPSIHATADAEEALGGASTVLLGVPAQTMRANLERWAPLLPEGATLVSLAKGIELGTLMRMSQVIISVTGAEPAQVAVISGPNLASEIAECQPAATVVACSDSGRAVALQRALNSGYFRPYTNADVVGTEIGGACKNIIALACGMAVGIGLGENTAAAIITRGLAEIIRLGTALGANGATLAGLAGVGDLVATCTSPRSRNRSFGERLGRGETLQSAGKACHVVEGVTSCESVLALASSYDVEMPLTDAVHRVCHKGLSVDEAITLLLGRRTKPE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_CHLTB
Sequence: MTNIHPTAIVEDGARIGNNVTIEPYAIVKKSVTLCDDVVVKSYAYIDGFTTIGRGTTVWPSAMIGNKPQDLKFKGEKTFVEIGEHCEIREFAMITSSTFEGTTVSIGNNCLIMPWAHIAHNCSVGNNVVFSTHVQLAGHVQVGDCVTIGSMVGVHQFVRIGSYSMVGAMSGIRRDIPPFTIGTGNPYALGGINKVGLQRRQVSFETRLALIKTFKRVFRSDESFQASLESVLEDFGEVPEVRHFVEFCRQPSKRGIERGVDCEASLEEPIDKKEGAFVES
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBX2B_RAT
Sequence: MAEGGGAEPEEQERRSSRPRPPSARDLQLALAELYEDEMKCKSSKPDRSTATAFKSPRTPPLRLYSGDQEYGGLHIAQPPTGKIVNELFKEAREHGAVPLNEATRSSSDDKAKSFTGGGYRLGSSFYKRSEYIYGENQLQDVQILLRLWSNGFSLDDGELRPYSDPTNAQFLESVKRGEIPLELQRLVHGSQVSLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAAVLIDDSVPTTKIQIRLADGSRLIQRFNSTHRILDVRDFIVQSRPEFATTDFILVTSFPSKELTDESVTLQDADILNTVILQQLK
What is the function of this protein?
Adapter protein required for Golgi and endoplasmic reticulum biogenesis.  Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis.  The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L.  VCPIP1 is also required, but not its deubiquitinating activity.  Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
UBX domain-containing protein 2B, NSFL1 cofactor p37, p97 cofactor p37.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to centrosome during mitotic prophase and metaphase.
Protein: OST48_DROME
Sequence: MMWKALLIAVLAIAHCQAVLETDANTLVLLDNLAIRETHSIFFKSLQDRGFKLTYKLADDSSLLLSKYGEYLYKNVIIFAPSVEEFGGDVSVERLAQFVDDGGNVLVAGSEKSGDALREFASECGFELDEENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVLKLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQSGVFHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELVQGEWRAFKASDIQLEFVRIDPFVRTYLKQTNTGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYSTTQVSVRPLEHTQYERFIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDEPVGRAAKEDKKSQ
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit, DmOST50, DrOST, OST5OP.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: HYPA_RIPO1
Sequence: MHELGITQNIIAIVAEQAKGIPVKRVTLEIGQLSAIMADSIRFCFDICCQGTVLEGATLEIIEILGRGKCRDCGQEIALFQPFGTCDRCGSIQLEIIQGQELKIKEMEIEEICV
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NODN_RHIME
Sequence: MHEISLSDVSSLVGQELGTSKWITIDQAMINLFADATHDHQFIHVDPNRAAAESPFGGAIAHGFLTLALLSVMNFSGMPKFREQTMGINYGFDRVRFISPVRTGSRVHGRFVLSDCRLRRASILMTAYNVTVEIENENKPALTANWIAIAQFNPKDRPKAG
What is the function of this protein?
Involved in the production of the root hair deformation (HAD) factor specifically on medicago.
What are the official names of this protein?
Nodulation protein N.
What is the protein family that this protein belongs to?
To the R.leguminosarum biovar viciae counterpart.
Protein: TPS1_CITSI
Sequence: MSSGETFRPTADFHPSLWRNHFLKGASDFKTVDHTATQERHEALKEEVRRMITDAEDKPVQKLRLIDEVQRLGVAYHFEKEIEDAIQKLCPIYIDSNRADLHTVSLHFRLLRQQGIKISCDVFEKFKDDEGRFKSSLINDVQGMLSLYEAAYMAVRGEHILDEAIAFTTTHLKSLVAQDHVTPKLAEQINHALYRPLRKTLPRLEARYFMSMINSTSDHLYNKTLLNFAKLDFNILLELHKEELNELTKWWKDLDFTTKLPYARDRLVELYFWDLGTYFEPQYAFGRKIMTQLNYILSIIDDTYDAYGTLEELSLFTEAVQRWNIEAVDMLPEYMKLIYRTLLDAFNEIEEDMAKQGRSHCVRYAKEENQKVIGAYSVQAKWFSEGYVPTIEEYMPIALTSCAYTFVITNSFLGMGDFATKEVFEWISNNPKVVKAASVICRLMDDMQGHEFEQKRGHVASAIECYTKQHGVSKEEAIKMFEEEVANAWKDINEELMMKPTVVARPLLGTILNLARAIDFIYKEDDGYTHSYLIKDQIASVLGDHVPF
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds which contribute to fruit flavor and aroma (PubMed:21818683, PubMed:14617067).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (+)-valencene (PubMed:21818683, PubMed:14617067).  No activity detected with geranyl diphosphate (GPP) (PubMed:14617067).
What are the official names of this protein?
Terpene synthase 1, CsTPS1, Valencene synthase TPS1, CsVS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: NUON_FLAPJ
Sequence: MNTLIYISALGILSLLAEIFNARKAIVPITIIGLLAIFGFNISEYNHLGSYYNNMMVVDKFSVAFSSLFIIITVFLVALSHEFYKEQKTKISDYVGIKVFLLSGAVAMVSFGNLSMFFLGIEVLSISLYILAASNRLNLKSNEAGMKYFLMGSFASGIILFGICLIYGATGSFDLNKILILINTQAYPQWYYIGIVFLLIGMLFKIATVPFHFWAPDVYEGSPALTTATMSTLAKIVAMATLYKLVTVLLPIQLYSIQIIIVCVAIASMLLGNIMALRQNNVKRMFAFSGISHAGFMVSTLLLTSNAASTLLYYASAYAIAGIAFFAVVMYVTKDKENETINSFNGLGKTHPLLAGILTAALLSMAGIPVLSGFFAKFFLLNQLVYTDWLIVVFVAIISSIISVGYYFKIIIAMYTKESEQTLPNVPVMYQIVAVVALILNIALGLFPNVVLKLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COQ6_CAEEL
Sequence: MKLPGGTIICARNASSYYDTVIVGGGMVGNAMACSLGANKSFQSKSVLLLDAGRSPSLASFKPGAPFNNRVVATSPTSIDTFKKLGVWDQINSHRTKKVNRLFVFDSCSTSEIEFERGQQEEVAFIIENDLIVGSLYEKLAEYKNVDVKTGAKVEDCSIPNALENMATIKLENGDVIETSLLIGADGVNSKVRHASNLDYTTFNYNQHGLVAIVNIETANGKNETAWQRFTTLGPVALLPLSDTVSGLTWSTSPEEAQRLKQLPSDQFVDELNSALFSQNNQIPLVNQTIFALNRMNPFRTETFGRKAEGTTPPHVITVQDKSRASFPLGFGNAHSYITTRCALIGDAAHRMHPLAGQGVNLGWSDVQILDKVLGDAVREGADIGSITYLREYDSAAQKHNLPVMVSVDLLNRLYRTDAPAIVAARAFGLNAFNSLGPVKNFLMNYLSAHR
What is the function of this protein?
FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis.  Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid.  The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
What are the official names of this protein?
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the UbiH/COQ6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL34_MYCLB
Sequence: MAKGKRTFQPNNRRRARVHGFRLRMRTRAGRSIVSDRRRKGRRTLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LEUC_RHILO
Sequence: MSAPRTLYDKIFDDHVVDRQDDGTCLLYIDRHLVHEVTSPQAFEGLRLSGRKVRHPEKTLAVVDHNVSTSPERKFGIKNEESRIQVEALAKNAKDFGVEYYSENDIRQGIVHIIGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQRKAKNMLVRVDGQLPEGVTAKDIILAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAADETTFAYVKDKPRAPKGAAWDAALAYWKTLQSDEGAHFDKVIVLDAAKLPPIVSWGSSPEDVVSVQGVVPNPEEITDENKRTSKIRALDYMGLTPGTKITDIALDRVFIGSCTNGRIEDLRAAAKVIEGKTVNPRVNAMIVPGSGLVKEQAEAEGLDKIFLAAGFDWREPGCSMCLAMNDDRLKPHERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIRDWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.