PharMolix/UniProtQA huggingface dataset:
Protein: SHRPN_MOUSE
Sequence: MSPPAGGAAVAADPASPVVLLAVHAAVRPLGAGQDAEAQPRKLQLIADPERPGRFRLGLLGTEPGAVSLEWPLEAICYTVRGPNQHELQPPPGGPGTFSVHFLDPEEAQQWAALVRDATAEGQNGSGSPAPAPAPAMCPISPPCSSMAQIPKATQPEVDLPQSSGNFKKEELATRLSQAIAGGDEKAAAQVAAVLAQHHVALNVQLMEAWFPPGPIRLQVTVEDATSVLSSSSSAHVSLKIHPHCSIAALQDQVFSEFGFPPAVQRWVIGRCLCMPERSLASYGVSQDGDPAFLYLLSAPREVSGQSLQNSKMDRKLGLFPQSLGLPHDLQPSSSSLPSPSQPGWSCPSCTFINASNRPGCEMCSTQRPCAWDPLAAAST
What is the function of this protein?
Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation (PubMed:17538631, PubMed:21455173, PubMed:21455180, PubMed:21455181).  LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways (PubMed:17538631, PubMed:21455173, PubMed:21455180, PubMed:21455181).  Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation (PubMed:17538631, PubMed:21455173, PubMed:21455180, PubMed:21455181).  LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex.  The LUBAC complex is also involved in innate immunity by conjugating linear polyubiquitin chains at the surface of bacteria invading the cytosol to form the ubiquitin coat surrounding bacteria.  LUBAC is not able to initiate formation of the bacterial ubiquitin coat, and can only promote formation of linear polyubiquitins on pre-existing ubiquitin.  The bacterial ubiquitin coat acts as an 'eat-me' signal for xenophagy and promotes NF-kappa-B activation.  Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis (By similarity).
What are the official names of this protein?
Sharpin, Shank-associated RH domain-interacting protein, Shank-interacting protein-like 1, mSIPL1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Synapse. Note=Enriched at synaptic sites in mature neurons where it colocalizes with SHANK1.
Protein: Y213_METJA
Sequence: MLNSIKLSAIVHATEDEDKVLEAIEFFIPENVDEEKIDLDVVETQGYFGNPIKIINVNVEGKEAKKIFKHIIDLIKSDDKNINKLKKDLHLRVEDNKFYVRFDKQKAYLGECRVVDGDDIIRAVFNFKIFTPKNKEEKVKEIVANELGF
What are the official names of this protein?
Uncharacterized protein MJ0213.
Protein: HIS1_GEOSM
Sequence: MPDFITIAIPKGRILQDSVALFKKIGIDCEELLSDTRKLVFENQEQKMRYMIVRATDVPTYVEYGCADLGIVGKDTLMEAEKDLYEPLDLKFGYCRLMVAEPVELSSKDDPSAWNNIRIATKYPNVTEKYFAAKGIQVELIKLYGSIELAPLVGLSERIVDLVSTGETLKQNGLAEIETIAEITCRLIVNRASMKTKHERISKIIEGLEQHI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF1_MALDO
Sequence: MSWQAYVDDRLMCDIDGHHLTAAAILGHDGSVWAHSSTFPKFKPEEITAIMKDFDEPGSLAPTGLHLGGTKYMVIQGEGGAVIRGKKGSGGVTVKKTGQALVFGIYEEPLTPGQCNMIVERLGDYLIDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-1, GD4-1, Pollen allergen Mal d 4.0301.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NUON_LEGPL
Sequence: MMTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLFISDDISHLMKLFIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLTLYLGLELMSLPLYAMTAIRRTDSDASEAAMKYFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMWAPDVYQGAPSSVTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHIGYALFGVLAASSAGYAAALYYILIYAVMSAAAFGLVVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTVGFFTKLLVLKALVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMYFDQPENEAIVKIGTGNTIVYSLNCLSLLYLGIFPGALIAACINAFAN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DENR_NEOFI
Sequence: MAEVAQNSPAEVQAKQVVYCGVCTLPPEYCEFGGTAKKCEEWLKDNHADLYQRLYSEEALSSNLSELSVSVRERAAKDAAKKEAKAAAAEARDAERKAAAKVQIKRVERNKRKHVTVITGLEVHGLENKKVAKELGKKFATGSSVTKSPAGVEEITVQGDVSEDVQEWLLELYGKEIPESNIELVEDKKKKASG
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_SHEAM
Sequence: MFGNLLTKIFGSRNDRTLKQLGKVVVKINALEAEYEKLSDEELKAKTAEFKARLEKGESLNELMAEAFATVREASKRVFEMRHFDVQLMGGMVLDSNRIAEMRTGEGKTLTATLPAYLNALTGKGVHVITVNDYLARRDAENNRPLFEFLGMSVGVNVAGLSHADKKAAYDADITYGTNNEFGFDYLRDNMAFSPNDRVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYMRVNKLIPSLIRQEKEDTEEFVGEGDYSIDEKARQVHMTERGQEKVEQLLTEAGLLAEGDSLYSAANISLLHHVNAALRAHTLFEKDVDYVVQNNEVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVRIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRKDMPDLVYLTAREKYQAIIADIKDCRERGQPVLVGTVSIEQSELLSRLLNQDKIPHQVLNAKFHEKEAEIVAQAGRSGAVTVATNMAGRGTDIVLGGNWKSEIEALENPSEADIARIRADWEVRHNAVVEAGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDNLMRIFASERVANMMKKLGMEEGEAIEHPWVTRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVYAQRNELMDAESIEETIKNIQADVVDGVISQYIPPQSVEELWDVPGLEDRLAKEFGLQLPVQEWLDKEDDLHEETLRERIVDTWRQAYEAKEQMVGTPVLRQFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQMLETLKHDVIAILSKVQVQAQSDVDEMEARRREEEARIQREYQHAEAESMASDNSELADMASHVPVVRDGEKVGRNDPCPCGSGKKYKQCHGKLT
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PSBL_BIGNA
Sequence: MSKSNPNKQSVELNRTSLYWGLLLIFVLAVLFSSYIFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PANB_ECO7I
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACUC_STAAM
Sequence: MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ
What is the function of this protein?
Role in growth on acetoin or butanediol.  Involved in the breakdown of these compounds used as a carbon source (By similarity).
What are the official names of this protein?
Acetoin utilization protein AcuC.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
Protein: ZAPD_YERP3
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRSASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RDMC_STREF
Sequence: MSERIVPSGDVELWSDDFGDPADPALLLVMGGNLSALGWPDEFARRLADGGLHVIRYDHRDTGRSTTRDFAAHPYGFGELAADAVAVLDGWGVDRAHVVGLSMGATITQVIALDHHDRLSSLTMLLGGGLDIDFDANIERVMRGEPTLDGLPGPQQPFLDALALMNQPAEGRAAEVAKRVSKWRILSGTGVPFDDAEYARWEERAIDHAGGVLAEPYAHYSLTLPPPSRAAELREVTVPTLVIQAEHDPIAPAPHGKHLAGLIPTARLAEIPGMGHALPSSVHGPLAEVILAHTRSAA
What is the function of this protein?
Involved in the biosynthesis of the anthracycline aclacinomycin which is an aromatic polyketide antibiotic that exhibits high cytotoxicity and is widely applied in the chemotherapy of a variety of cancers.  Catalyzes the removal of the methoxy group from the C-15 position of aclacinomycin T and A to yield 15-demethoxyaclacinomycin T and A, respectively.
What are the official names of this protein?
Aclacinomycin methylesterase RdmC.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RdmC family.
Protein: PDAD2_METMA
Sequence: MIPRKAFLTKGTGVHKDRLASFELALRDAKIEKYNLVSVSSILPPNCKLVPREEGLAELKPGAIVHCVLARNDTNEPHRLMASAIGTAVPVNEENYGYISEHHSFGEEEIIAGEYAEDLAATMLATTLGIEFDAEMAWHEREQVYKASGHIFDTFHMCQTAKGDKDGKWTTTVAAMVFVTSKC
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase 2, PvlArgDC 2.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: Y587_TREPA
Sequence: MIAQYQRAASLWTLSDTHAILDRLFQTDAMIRSGGTPLQGPLMQLCLYAIVVHAGRAPHRYCTTLQEQCGLQNEIY
What are the official names of this protein?
Uncharacterized protein TP_0587.
Protein: MTNB_EXISA
Sequence: MTVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVLVDATGQLIGEQSGKPSAETLLHVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQEIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGDAGAVLIRNHGITVWGETPAAAKRYLEAYEFLFSYSLKLRALGVHS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: PEBA_PROM9
Sequence: MFDSLVDFLKTNIDELNGHELQISNEFKEHHNKDSKYIIKNWLFSSPEYRKWRITRLDGGKNIQVFNTVAYPNFDSELPILGADILWFGTAKKLLAILDYQPLIQENKYLEKYCSSLGMIKKKYSAFDNNKMKNIYDSKKYFSPWVIICRGNKLNLDRDLNDVFHAFINNYLNLNKSNPVNQFLNLEEIKINQIKYDKYSFEKDPADKLFKSFFGEKWTKKFINKFLFTLNNEIIL
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: RL29_ALKOO
Sequence: MKTKEMRDMTNAELDQRLAELKGELFNLRFQLATGQLENPLRIRNVRKDIARAKTIIRENELKQARA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CLPX_SYNP6
Sequence: MSRYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDGNANPAPPPGSPKPATAATTSHQGPRKPKRSLTLSQIPKPHDIKRYLDHHVIGQNEAKKMLSVAVYNHYKRLAYQQSAEEAGETIEIQKSNILLIGPTGCGKTLLAQTLAKLLDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDIEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTRNILFICGGAFVGLEKLVDRRLGKKSIGFVHPEESKTKEQRAAAILRHMEPEDLVQFGLIPEFIGRMPVTAVLDPLDETALTEILTEPRDALVKQYQKLMHMDSVELEFRQDAIEAIAREAFRRKTGARALRGIVEEIMLEVMYELPSRQDVTHCTITREMVEKRSSADVLLLPSSLPTPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SUHB_NEIMB
Sequence: MNPFLNTAFKAARRAGQMMIRAAGNLDAVKTDSKAFNDFVSDVDRNSEIILVEALKEAYPHHKITCEESGSHGKAAAEYEWIIDPLDGTTNFLHGHPQYAISMALLHKGVLQEALVYAPERNDVYMASRGKGALLNDRRIRVSNRIELNRCLIGTGFPVVDQSMMDKYLAILKDFLAKTAGGRREGAASLDLCAVATGRFDGFFEFNLKPWDIAAGALIVQEAGGIVTDMSGEDGWLESGDIVAANPKVLAQMLKIISAHV
What is the function of this protein?
Might be part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP).  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.  This subunit may play a central role in organizing the structure.
What are the official names of this protein?
Putative Nus factor SuhB, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_AGRFC
Sequence: MKPGEIIAAEGTIELNAGQPTVTIEVANSGDRPVQVGSHYHFFETNAGLLFDRDKARGMRLDIPAGTAVRFEPGQKREVTLVPLSGKREVYGFRQQIMGRL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEVS_FRUSA
Sequence: MTKEHKKMYKAGKYWAVATLVSASILMEVGVTTHADAVENNKYDGTANVNIDCQANVDGKIISTDDNATSGSTKQESSIANDNATSGSTKQESSIANDNATSGSTKQESSIANDNATSGSTKQESSVANDNATSGSTKQESSVANDNATSGSTKQESSVANDNATSGSTKQESSVANDTKTAVVDESKNTSNTENDNSQLKQTNNEQPSAATQANLKKLNHEAAKAVQNAKIDAGSLTDEQINELNKINFSKSAEKGAKLTFKDLEGIGNAIVKQDPQYAVPYFNAKEIKNMPASYTVDAQTGKMAHLDVWDSWPVQDPTGYVSNYKGYQLVIAMMGIPNTPNGDNHIYLLYNKYGDNDFSHWRNAGSIFGTNENNVYQEWSGSAIVNDNGTIQLFYTSNDTSDYKLNDQRLATATLNLDVDDNGVAIKSVDNYHILFEGDGFHYQTYDQFANGKDRKNDDYCLRDPHVVQSENGDRYLVFEANTGMEDYQSDDQIYNWANYGGDDAFNIKSFFKLLNNKNDRELASLANGAIGILKLNNDQTNPKVEEVYSPLVSTLMASDEVERVNVVKLGDKYYLFSATRVSRGSDRELNAKDITIVGDNVAMIGYVSDNLMGKYKPLNNSGVVLTASVPANWRTATYSYYAVPVEGHPDQVLITSYMSNKDFASGEGNYATLAPSFIVQINPDDTTTVLARATNQGDWVWDDSSRNDNMLGVLKEGAVNSAALPGEWGKPVDWSLINRSSGLGLKPHQPVNPSQPTTPATPVNPSQPTTPATPVNPSQPTTPATPVNPSATTTPATPVNPSATTTPAKPVNPSQPTTPAKPVQAGQATATNFVDQRLPQTGENNSQSQTMSFIGILLAMFGSLLGFLGIKKRRND
What is the function of this protein?
Fructosyltransferase that catalyzes the polymerization of the fructose moiety of sucrose to produce levan polymer and the fructo-oligosaccharide (FOS) 1-kestose.  Also displays sucrose hydrolase activity.
What are the official names of this protein?
Levansucrase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 68 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: SYS_ERWT9
Sequence: MLDPNLLRNEPDAVAEKLARRGYKLDVDTLRAHEERRKVLQVETENLQAERNSRSKSIGQAKARGEDIEPLRQEVNALGERLDAAKAELDALLTCINDFSMAIPNIPADVVPLGKDDSENQEISRWGEPRQFDFTVRDHVELGEMAAGLDFAAAVKLTGSRFIVMKGQIALMHRALSQFMLDLHTEQHGYQETYVPYLVNHASLYGTGQLPKFGEDLFHTRPLDEEASSSNYALIPTSEVPLTNLVRDEILEEETLPLKMTAHTPCFRSEAGAYGRDTRGLIRMHQFDKVEMVHITRPEDSMDALEELVGHAEKVLQLLNLPYRKVLLCTGDMGFGAQKTYDLEVWLPAQDTYREISSCSNMGDFQARRMKARCRPRGESKTRLVHTLNGSGLAVGRTLVAVLENYQQADGRIEVPEVLRPYMKGLHFIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCVB_SCHPO
Sequence: MPFLKPSKVSLKRILQGNPPKPIGLTEYGHLLRLVGLREADSKEENERTILKLNEGIIQMHAIERLDTSFIKEPFRTLNHAINAESLPSLPDQEPWNVFQNAKKRDGQYFAVYSKLKDDSSNESPNKQ
What are the official names of this protein?
Uncharacterized protein C777.11.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPB_GALBE
Sequence: MRINPTTSGPGVSTLGRKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNFEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HMDH_STRPU
Sequence: MLSRLFLAQGRFCSSHPWEVIVCTLTLTICMLSMNYFTGLPRICGWNYECAPQVKESSLSSDVLVMCIMRTLAVAYLYLQFTKLRTTGSKYILGIAGLFTIFSSFLFSSAVIHLFGLELTGLNEALPFFLLLIDLTKASALTKFALSSTTQNEVVDNIARGMAILGPTITLDTVVTTLVISIGTMSSIRKMEVFCCFGILSLIANYFVFMTFFPACLSLVLELSNSNKYGRPVWHLGRFAEVLEEEEDRKPNPVVQRVKMIMRTGLVLVHAHSYWLASNDTELMSRDMLYDGNLLTDKKIDPTMPLWEFYATRLWPPTLDYILTAILATVLASHYIFFSDLATYPEKRVSIMEGHEVVNPGSDHEDASEVETIGTLSSSPSTSDVRVIESMTSRTQACQTDPVTASPRNSRSSSPVSSHSVKPARFTIGSSGSGSEDEEEEVIKEEEVEWVLETELKAPRPMPELLEILNVGKGPNALTDDEVQLLVGAKHIPAYKLENILDNPERGVAVRRQIISKLLPITDALEKLPYASYDYSFVSGACCENVIGYMPVPVGVAGPLLLDGQEFQVPMATTEGCLVASTNRGCRALRSAGGIHSVLIGDGMTRGPLVRLPSAQEAGAIKQWLEVPENFAAIKERFESTSRFAKLKSIQTALAGRYMFLRFKALTGDAMGMNMISKGTEQALHALQTMFPNIEIMSLSGNYCTDKKVAAINWIEGRGKSVVCEATVPAHIVQQVLKTSASALVDLNIHKNLVGSAMAGSIGGFNAHAANIVTAIYIATGQDAAQNIASSNCMTLMETRGPKGGDLYLSCTMPSIELGTVGGGTVLPPQSACLQMMDVKGSNIHGSGLNASQLARIVCATVMAGELSLMSALAAGHLVKSHMKHNRSALNIASPLPSIDEVATHRRSKSVDFSALKESSAAAPGTCTANAS
What is the function of this protein?
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis.  It is the rate-limiting enzyme of sterol biosynthesis.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CRPI_PERAM
Sequence: MKTALVFAAVVAFVAARFPDHKDYKQLADKQFLAKQRDVLRLFHRVHQHNILNDQVEVGIPMTSKQTSATTVPPSGEAVHGVLQEGHARPRGEPFSVNYEKHREQAIMLYDLLYFANDYDTFYKTACWARDRVNEGMFMYSFSIAVFHRDDMQGVMLPPPYEVYPYLFVDHDVIHMAQKYWMKNAGSGEHHSHVIPVNFTLRTQDHLLAYFTSDVNLNAFNTYYRYYYPSWYNTTLYGHNIDRRGEQFYYTYKQIYARYFLERLSNDLPDVYPFYYSKPVKSAYNPNLRYHNGEEMPVRPSNMYVTNFDLYYIADIKNYEKRVEDAIDFGYAFDEHMKPHSLYHDVHGMEYLADMIEGNMDSPNFYFYGSIYHMYHSMIGHIVDPYHKMGLAPSLEHPETVLRDPVFYQLWKRVDHLFQKYKNRLPRYTHDELAFEGVKVENVDVGKLYTYFEQYDMSLDMAVYVNNVDQISNVDVQLAVRLNHKPFTYNIEVSSDKAQDVYVAVFLGPKYDYLGREYDLNDRRHYFVEMDRFPYHVGAGKTVIERNSHDSNIIAPERDSYRTFYKKVQEAYEGKSQYYVDKGHNYCGYPENLLIPKGKKGGQAYTFYVIVTPYVKQDEHDFEPYNYKAFSYCGVGSERKYPDNKPLGYPFDRKIYSNDFYTPNMYFKDVIIFHKKYDEVGVQGH
What is the function of this protein?
Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins.
What are the official names of this protein?
Allergen Cr-PI.
What is the protein family that this protein belongs to?
Belongs to the hemocyanin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: HIS8_HALSA
Sequence: MELRDLSDHVEYRAGRGIEEVARELGRDPSEFVKLSSNENPHGPSPKATIAIREAATGVHRYPKAVHADLTGALADRWDVGDDQVWVANGGDGALDYLARATLDPGDSVLVPSPGFTYYGMSARFHHGNVAEYDVAEGADGFEMTADAVVDAYDGERVVYLTTPHNPTGARFTLDEIVAVADRTDEDTLVLVDEAYGEFTETPSAVTLFDGQPAGGHAPRDDIAVLRTFSKAYGLAGIRLGYAVVPDSWADAYARVQTPFAASVIACQAGVAALDDDDHVEATTDSVAWGRDYIHDELAARTYESHGNFVLANVGDAGRVAEAAKREGVLVRDCTSFGLPEHVRITIGTRSETERAVAVLNEVCDT
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PUR7_MYCTA
Sequence: MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFFFGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKVCGIALPPGLVEASRFATPLFTPATKAALGDHDENISFDRVVEMVGALRANQLRDRTLQTYVQAADHALTRGIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDKQFVRSWLTGSESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.