PharMolix/UniProtQA huggingface dataset:
Protein: UREG_BLOFL
Sequence: MSNDKAKHPMKVGIGGPVGSGKTALIEVLCKKMKTDYQLAVVTNDIYTKEDQQILINAHALESDRIIGVETGGCPHTAIREDVSMNLLAIEELIDKFNNLDIIFIESGGDNLSATFSPELSDWNLYVIDVAAGDKIPRKGGPGITKSDFLIINKIDLAQYVGASLDVMKFDTHTMRNNRPWTFTNLKTGYGIESVINFLREKKLINNKM
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA174_XENTR
Sequence: MRKRKLSDGVRCSARQKNRSCSGAQSSTDHEADTYGPKKKAASSNNTEKESSKKLRKDEKGPVEADENELLNKIDNAASNESSNVNDSQQSEKSITNTKDNGTRCSKLRANTRLPSSPVSDLNEVSCNGLTDDSGDGTGFIHKTCSEPSKLREIYLNGSPFVDEDSNQPMPLGLFFENADLMQDLPPAVPSCASMSRRELRNLHFRAKEEDEDDDDYVDGLANEGNI
What are the official names of this protein?
UPF0688 protein C1orf174 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0688 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_STRPC
Sequence: MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFITVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTVKENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIAFPKEYLGEGIDPKIKETVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDAKNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFADYDLILGPTTPAVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVGLQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MURG_CAMJ8
Sequence: MTIALTGGGTGGHLAIVRCLLESAIKKNIECVYIGSQNGQDKAWFENEVRFKEKFFLSSKGVVNQSKFGKISSLLHTLKLSKDCREIFKKYHIQAVFSVGGYSAAPASFAALFSHLPLFIHEQNSKSGSLNMLLKPFATKFFSAFEKEISPYPVADKFFDNARIRKELKNIIFLGGSQGAQFINELALNLAPKLQEQNIKIIHQCGKNDFEKCKKHYQSLNIQADIFDFSLNLEEKMKNADLAISRAGASTLFELCANTLPTIFIPYPYAAKNHQYFNAKFLQDQALCQIFMQNSINLDEFFKSILKLNLENISTRLQNITQKNGADMLIQKALFDNLTFIR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYEP_DROME
Sequence: MSIKLKANLNNPPISGLATAHLINGTVPVEIVWSKEETSLQFPDNRLLVCHSNNDVLRALARAAPDYKLYGETAIERTQIDHWLSFSLTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSRYEFLAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAKVKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFNKKVIDPIAPRYTALEKEKRVIVNVAGAKVERIQVSVHPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDDPSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSGLKVNAPDAKATKKASSPVSSSGQASELDSQISQQGDLVRDLKSKKAAKDQIDVAVKKLLALKADYKSATGKDWKPGQTSASSAPVPAASSSSANDAVSVNASIVKQGDLVRDLKGKKASKPEIDAAVKTLLELKAQYKTLTGQDWKPGTVPTTAAPSASAAPSVGVNDSVAQILSQITAQGDKVRELKSAKADKATVDAAVKTLLSLKADYKAATGSDWKPGTTAPAPAAAPVKVKQEKNPDPASVLTVNTLLNKIAQQGDKIRQLKSAKSEKSLVEAEVKLLLALKTDYKSLTGQEWKPGTVAPAPTTVNVIDLTGGDSGSDVGSVLSKIQAQGDKIRKLKSEKAAKNVIDPEVKTLLALKGEYKTLSGKDWTPDAKSEPAVVKKEASPVSMASPAKDELTQEINAQGEKVRAAKGNKAAKEVIDAEVAKLLALKAKYKEVTGTDFPVAGRGGGGGGGSAKKAPKEAQPKPAKPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPETQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY
What is the function of this protein?
Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA.
What are the official names of this protein?
Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: LOLA_CUPPJ
Sequence: MRKRILVSACAALAVFAAHMPTALAAATDQLQSFVTGVKSAKGEFTQRQVKGQGDSLKVTGTSSGSFVFSRPGKFTWRYAKPYEQLLQADGQTLYIYDKDLNQVTERKLDGALGSSPAAILFGSNDLEKNFTVKNGPTRDGVEWLELTPKSKDTQFERIGIGFKGGNLEAMELRDAFGNTTLLTFSAMQKNPQLPANAFRFTVPKGADVMKQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YCX1_CHLMO
Sequence: MSRKKTIKDYENLAATRNHEVISVSNKETPSQGDITLLCKTCNKEFTTTTISYQNARKTGCPHCKATSASLYWTGRARTKTPEQAKKNAEIKEHINKTRKEKGKAFANIKNKEDLKEKLTNDLYLPNGEKNAYNDFILKRLNDPVTGKMMEKHHIIPLHAGGPDEKWNLISLTPEDHIEAHNLRYLVYNETGDKNTIKFRNKTPNVTDQISKAKALGNETRRAQGTGIYEPGMSSKAGKIGGSVKSVEKDLKQSTKMTSGVYDALYNGSRWKHTKTNTEIVIPPNTIVKMPQLVEKLIEALPPCEEKTRLAGAKLTTATSALARVIKGKNEGGRSSYFGWSICKE
What are the official names of this protein?
Uncharacterized 38.5 kDa protein in psbA intron 1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXB_RUTMC
Sequence: MKLVIDDACYAYREIFDHFGEITAISGSDINANSVKDADVLIIRSRTKVNQELLSGSQVKFIGSTVVGLDHIDQNYLKTKGTQFFSAQSCNSMAVAEFVISTIVNLVDELNFDYQKKTLGIIGVGNVGTKLAEKAKLMGIKTLLNDPPRQIRENLDNFVDLNTALSADIVTFHTPLTVNGEHPSYQLLNENNFHHITNKTILFNAARGGVIKETIWKKHKTLANIIDCWEDEPNINPSLQNTAYLATPHIAGHSVDAKFMGSFMVYEALCTFLGKKQDKNIRNLINLSELSIDKSNLKDTLNEIYDFQQDANAIKDVNNFEDYRRNYPIRYEWHHFKSKTVLPIA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_ECODH
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: FADR_ECO27
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1669_VIBC3
Sequence: MLNINSDAKLKDLLEFPCSFTYKVMGHAKPELPERVLEVIQRHAPGDYSPRVKPSAKGNYHSVSVTIHATSIEQVEILYKELGEIDIVRMVL
What are the official names of this protein?
UPF0250 protein VC0395_A0469/VC395_0960.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: LSPA_STRP1
Sequence: MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLLICLWKEEDYGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF347_IIV3
Sequence: MSIDPKLWGNAFWSTLHHVAAGYNDHPSLGARQVMTNFIQSIPVLLPCAECQDHAFDYIGRADLDRVVSSRRQLFLFFFNFHNHVNARLNKPQLAAKTVFQRYRVPFDGEAAAATTEPPFHWSPWLTTALAVILVVVVAGIGHRSRFK
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.
What are the official names of this protein?
Putative FAD-linked sulfhydryl oxidase 096R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 347L family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSD13_MOUSE
Sequence: MKDVPAFLQQSQSSGPGQAAVWHRLEELYTKKLWHQLTLEVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQATKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRDTDRQWLIDTLYAFNSGAVDRFQTLKCAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNKVELLVMKALSVGLVRGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLELWCTDVKSMEMLVEHQAQDILT
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit RPN9, 26S proteasome regulatory subunit S11, 26S proteasome regulatory subunit p40.5.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S11 family.
Protein: CHO2_AJECH
Sequence: MSEQANSSGIESLSNGLRERNAQTSKPIGDGEVTSQSLEDKLQIEEGDAADAEKKTFGRTPDGKVFTVPPTRDMVSQLLSPSEPKNISDIFVLAILGCHILLLWCLPSSFRIAAFAVIFLFWRASYNIGIGWLLHMQSNGRTLVCWAKKSNIFVNPSTGQNPHPTLYKMLKWELETKISEQYSFDEAPTEYNTWLVFRRVVDLILMCDFTSYCLFAIACGGRPAGESFIMLALRWTTGMSLVLFNLWVKLDAHRVVKDFAWYWGDFFYLIDQELTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISILAHAAQFAFLVLVENPHIEKTYNVPPPRKRVAVDTDTKLQEDENSHEGSVVSDIANSAPVMPALQPVSMHNLLGLHNIDLYRSTDQSVLLAQLLFFALTTMTPSTPVYQFCFVLNAALWRIWYSVGIGYILNRQSNCKMWTRHFVKYGESNHEAWRQWKGTYHLSMTMTYASFIAAAWKMYSFPQDWGYGLVLLRHILGASLIALQIWTSSSIYESLGEFGWFFGDFFFDQSPKLTYSGIYRFLNNPERVLGLAGVWGAVLITSTKSLVFLALLSHTLTLAFIQLVERPHMQKLYGQSLRRDAGLVRSLKRSLPPSLKQIHGSVDKILDESFEFIEEFIEAARPKLATGVQTFVKDTSALFQKYPARVTISRLEPDLAGYDLKDYSITLEGTQPSQPAQFERASDKEGERARSMQFRRGEQENLIFEYGAPIKVKWTAPLNHSKKDWIGLYMVTDNTSREVTSVASQGRWIATNQASFDSETCEQGLISSDIVLKITREDCEPIDVASGEMVFSGDKLWWTQGVFEFRYHHNGKHNVMAVSRPFEIRIGRFDEDIVEADNYGLVRAAVEAALLPVVQNCFDRDPEIAPQTAEEHYGCLVERDGKYSKRVVFAVQHIVRADGNVRNLAWRICNAKKVLAPYSMSRSNGASTPTTEHED
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1714_CLOPE
Sequence: MENRFEISMLIDYYGTLLTEKQFNVMTLYYNEDLSLAEIAEINKTSRQAIYDLIKRCSKQLHSYDEKLKLSKKVDKRYRIKEELMAELNKNSNLDENIKKYIDEKLEEIINA
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein (By similarity).
What are the official names of this protein?
UPF0122 protein CPE1714.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RS6E_METBF
Sequence: MANFKVVVSDPKEGRAYQIDVKDAEANALIGKSIGDVVDGAVFGLSGYKVKITGGCDGSGFVMKPDLLGPRRQRILMAVGVGYTPKHPGQRRRKMVRGKEVAPDIVQINAKVVEYGSKSIKALLGLEAPAEAPAEAPAE
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: PP2A1_SCHPO
Sequence: MSVSGKIGEVDRWIEQLSRCEPLSEEDVIQMCDLAKEVLSVESNVQSVRCPVTVCGDIHGQFHDLMELFNIGGPSPDTNYLFMGDYVDRGYHSVETVSLLIAFKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWQYFTDLFDYLPLTALIEDRIFCLHGGLSPSIDTLDHVRILDRVQEVPHEGPICDLLWSDPDDRPGWGISPRGAGYTFGPDIAEAFNHNNGLDLIARAHQLVMEGYNWTTNHNVVTIFSAPNYCYRCGNQAAIMGIDDHINYAFIQYDTAPRKEELHVTRRTPDYFL
What is the function of this protein?
Essential role in cell cycle control.  PP2A may be involved in controlling the entry into mitosis, possibly acting as an inhibitor.
What are the official names of this protein?
Minor serine/threonine-protein phosphatase PP2A-1 catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
Protein: ARGC_RUEPO
Sequence: MTHKIAILGASGYTGAELVRLIAEHPNMEIVALSGERKAGQSMAEVFPHLRHLDLPVLCKIDEIDFAGVDLCFCALPHKTSQEVIRALPATLKIVDLSADFRLRDPEAYRTWYGNEHVALEQQAEAVYGLTEFYRDQIRTARLVAGTGCNAATGQYVLRPLIAAGVIDLDEIILDLKCAVSGAGRSLKENLLHAELSEGANAYAVGGTHRHLGEFDQEFSALAGRPVQVQFTPHLIPANRGILATTYVRGDAQTVFQTLAAAYADEPFVHVLPFGETPSTHHVRGSNHCHIGVTGDRIAGRAIVIAALDNLTKGSSGQALQNANLMLGETETTGLTMAPLFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT46_MOUSE
Sequence: MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDACVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSDQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDELSEFEIGTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGSSYGKEDQEPKADGPDDVSSQSLWPGDVGYGSLRIKEEQISPSHYGGSELPSSKDTAIQNSLSEQGSGDGWQPTGRRKNRKNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAHIDEGLLGGETSYLGPPLTPEKEEALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIKHGSRRHGVCADCAGRGVGTPLDHGGGGEGSPEALFAGEGPYLEDPDDPRGEAEEELVEDEDEDVAKWKDDVGLAHEDALLGDDKDDEDSPQGPHSPSGEPDKDFAWIS
What is the function of this protein?
Functions as a transcriptional repressor for PRDM1.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 46, BTB-ZF protein expressed in effector lymphocytes, BZEL, BTB/POZ domain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y075_OSHVF
Sequence: MSFIVEKINCNSLPLKRKTRFAAGHDVYTPYDVVFEVGQTEAKVYTNLVVKSVPEGCAIIVAGRSGLMHGNGMRAIDDEITVGSEDELIITLTRKTGLDKRVVLKSETRVAQIIADTTQDVKLVELPISTYGLDVNHGDVPVYKFNTHWRLEAMPWLRDYQGNRNEVYLRLKSEHFNGIIDPDYKGDIIYMSETPFERLDELYVEVRQFSGETYLGGESPDNVVRGEGGFGSTGGH
What are the official names of this protein?
Uncharacterized protein ORF75.
Protein: VPI1_SCOJE
Sequence: MKWGALLCIFGFLAFCSVLDRGLGWIPDIWQKCSSKNEEFQQCGSSCPETCANHKNPEPKSCAAVCFVGCVCKPGFIRDDLKGSICVKPEDCSK
What is the function of this protein?
Recombinant protein inhibits both alpha-chymotrypsin (Ki=97. 1 nM) and elastase (Ki=3700 nM).
What are the official names of this protein?
Venom peptide SjAPI, Ascaris-type protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: T132A_HUMAN
Sequence: MCARMAGRTTAAPRGPYGPWLCLLVALALDVVRVDCGQAPLDPVYLPAALELLDAPEHFRVQQVGHYPPANSSLSSRSETFLLLQPWPRAQPLLRASYPPFATQQVVPPRVTEPHQRPVPWDVRAVSVEAAVTPAEPYARVLFHLKGQDWPPGSGSLPCARLHATHPAGTAHQACRFQPSLGACVVELELPSHWFSQASTTRAELAYTLEPAAEGPGGCGSGEENDPGEQALPVGGVELRPADPPQYQEVPLDEAVTLRVPDMPVRPGQLFSATLLLRHNFTASLLTLRIKVKKGLHVTAARPAQPTLWTAKLDRFKGSRHHTTLITCHRAGLTEPDSSPLELSEFLWVDFVVENSTGGGVAVTRPVTWQLEYPGQAPEAEKDKMVWEILVSERDIRALIPLAKAEELVNTAPLTGVPQHVPVRLVTVDGGGALVEVTEHVGCESANTQVLQVSEACDAVFVAGKESRGARGVRVDFWWRRLRASLRLTVWAPLLPLRIELTDTTLEQVRGWRVPGPAEGPAEPAAEASDEAERRARGCHLQYQRAGVRFLAPFAAHPLDGGRRLTHLLGPDWLLDVSHLVAPHARVLDSRVASLEGGRVVVGREPGVTSIEVRSPLSDSILGEQALAVTDDKVSVLELRVQPVMGISLTLSRGTAHPGEVTATCWAQSALPAPKQEVALSLWLSFSDHTVAPAELYDRRDLGLSVSAEEPGAILPAEEQGAQLGVVVSGAGAEGLPLHVALHPPEPCRRGRHRVPLASGTAWLGLPPASTPAPALPSSPAWSPPATEATMGGKRQVAGSVGGNTGVRGKFERAEEEARKEETEAREEEEEEEEEMVPAPQHVTELELGMYALLGVFCVAIFIFLVNGVVFVLRYQRKEPPDSATDPTSPQPHNWVWLGTDQEELSRQLDRQSPGPPKGEGSCPCESGGGGEAPTLAPGPPGGTTSSSSTLARKEAGGRRKRVEFVTFAPAPPAQSPEEPVGAPAVQSILVAGEEDIRWVCEDMGLKDPEELRNYMERIRGSS
What is the function of this protein?
May play a role in embryonic and postnatal development of the brain.  Increased resistance to cell death induced by serum starvation in cultured cells.  Regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation (By similarity).
What are the official names of this protein?
Transmembrane protein 132A, HSPA5-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM132 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: FOXR1_MOUSE
Sequence: MGNECFLTFTTTHLSEAEQKLALYRLQLVEPPKLPLEKKTNPDKDGPDIKPNLWMWVNPNMVYPPGKLEVAVKEEDQSALSAFQPALKEEEDSCSEASEVQQPLPPCRQKRKQRRSTVPLPLAPGRRAPLENPWRLPQAISPEGRLWSRPPLHYFHLIALALRNSPPCGLSVQQIYSFTREHFPFFRTAPEAWKNTVRHNLSFRDSFEKVPASRQGGASTGPRSCLWKLTEEGHRRFSKEARTLASTQLQSIQQCMSQPGVKPFLFDL
What is the function of this protein?
Transcription factor which acts as both an activator and a repressor (By similarity).  Activates transcription of a number of genes including the heat shock chaperones HSPA1A and HSPA6 and the antioxidant NADPH-dependent reductase DHRS2 which are involved in protection against oxidative stress (By similarity).  Required for normal brain development (PubMed:34723967).
What are the official names of this protein?
Forkhead box protein R1, Forkhead box protein N5.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Located in the cytoplasm of spermatocytes and strongly accumulates at the perinuclear region in elongated spermatids.
Protein: NUON_AZOSB
Sequence: MNFVVPDFYPATAEIFVAVMALVIMLATTFARSVARGLAYGLTLVTLIGAAIITYNTANPRAVTTFSNMFIGDLLGDVLKLLIYFSMAVALLYGRSYLADRKLDKPEYYVLALLMTLGMMVMVTSNHLLSMYIGLELMSLSLYALVAFDRDSARGTEAAMKYFVLGALASGLLLYGMSMLYGATGTLEISGIAKSVYNQAANDTVLLFGLVFLMAGICFKLGVVPFHMWIPDVYHGANTAVTLIIATAPKLAAFAMAVRLLVWGLFDVAEHWQTMLMFVAVLSIVLGNLAAIAQTNLKRMLAYSGISHMGFMLLGLLSGVVDGDPHYALDAYSAAMFYAISYVIMSLASFGMIILLSRAGFEAENIDDFKGLNKRSPWFAAMMMFVMFSMAGIPFFIGFFAKLAVLQAVVAAGYIWVAVVAVLMSVIGAFYYLRLVKVMYFDEPADATPIQAPAELRVFLSANGLAIAAIGLAPQGVMTLCTFVLLASTQP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNTP_ENT38
Sequence: MNISATILLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAIETLTPLIGWSLGMLASQFILEWNHWIAFTLLVFLGGRMVIEGFRNTPDEDDAPQYRHGFWILVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTIGMMVGRFIGPLLGKRAEILGGIVLIGIGGQILWSHFAG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13_GEOSM
Sequence: MKTQVAKKEEVTRDWYLVDVDNKVLGRVATEIANVLRGKNKPTFTPSVDTGDFVIVVNAEKIALTGRKLADKVYYSHSSYPGGLKEITAGKLLDKKPEELLKKAVKGMLPKNKLARHMLKKLKIYSGGAHPHAAQNPKNLNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL6_SALHS
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MTNC_LEPIN
Sequence: MNIKTFEFYLFDIEGTTTPIEFVHKILFPYSVEKFDSFFQSNLLEKEWIEKLILEGKNDTTYSGKLSDSAFDLSEYCKHLVSLDRKSGILKEIQGRIWKSGYENGELKSSMFSDVPSFLKKIQASKKKSAVYSSGSIQAQKLIFEYSDFGNLTHFFYAYFDTGVGGKRESSSYSKISEQLGVAPEKILFFTDIKEEADAAKEAKLHSAILERPGNYPQPQHSHFKISSFEGLNP
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.