PharMolix/UniProtQA huggingface dataset:
Protein: METE_THESQ
Sequence: MKAYAFGFPKIGEKREFKKALEDFWKGKITEEQFEEEMNKLRMYMVENYRKNVDVIPSNELSYYDFVLDTAVMVGAVPERFGEYRGLSTYFDMARGGKALEMTKFFNTNYHYLVPEIETEEFYLLENKPLEDYLFFKSKGIETAPWVIGPFTFLYLSKRNGEWIRRPNQMEKLLESLVSVYKEVFEKLVENGCKEILVNEPAFVCDLEKAHWDLILNVYRELSEFPLTVFTYYDSVSDYEACVSLPVKRLHFDFVSNEENLKNLEKHGFPEDKKLVAGVINGRQPWKVDLRKVASLVEKLGASAISNSCPLFHLPVTLELENNLPGGLKEKLAFAKEKLEELKMLKDFLEGKTFDLPNVSFEDFAVDLQAVERVRNLPEDSFRREKEYTERDRIQRERLNLPLFPTTTIGSFPQTPEVRKMRSKYRKGEISKEEYEAFIKEQIKKAIELQEEIGLDVLVHGEFERTDMVEFFAEKLNGIATTQNGWVLSYGSRCYRPPIIYGTVTRPEPMTLKEITYAQSLTEKPVKGMLTGPVTIMSWSYYREDIPEREIAYQIALAINEEVKDLEEAGIKIVQIDEPAFREKAPIKKSKWPEYFEWAINAFNLAANARPETQIHAHMCYSDFNEIIEYIHQLEFDVISIEASRSKGEIISAFENFKGWIKQIGVGVWDIHSPAVPSINEMREIVERVLRVLPKELIWINPDCGLKTRNWDEVIPSLRNMVALAKEMREKFES
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: THIE_DICTD
Sequence: MNKKEKLELLKDFNLYCLTCEEYSIGRKNIDVVREILEAGVKIIQYREKKKPMREKYHEVVKIRDLTAKYNALLIVNDHLDLTKIVEADGVHIGQEDYPIEVAKEFLGENFIIGLTTHTKEQVMEALRKGADYIGLGPIFPSYTKEKPHPPIGIEILDWAIKNISIPVVAIGGIKESNIHEILNLGAKCIAMVTEIVSSPNIYEKTRKIIHILEGYKNGKYIA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: YIDD_STAA1
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y4577_RHOP5
Sequence: MLVHIPEVLSRDQVRHCRELMARADWVDGRITAGHQSAQVKRNLQLPEGTPEARELSELVHGALSRHPLFMSAALPKTIFPPLFNRYDADGEMNFGSHVDNAIRTVPGTGVRVRTDVSSTLFLSDPDEYDGGELVVEDTYGSHAAKLPAGDMVVYPGTSLHHVTKVTRGSRIASFFWTQSLIADVTRRAMMFDLDMSIIRLNADHPDHPSVLSLTGLYHNLLRQWAEV
What are the official names of this protein?
PKHD-type hydroxylase RPE_4577.
Protein: GATB_SORBI
Sequence: MALTLLRGMRTPVSSGSNPGLFFAVLRPRLSRFTARAESAQATEPKAAPPPRSIQLATKEAAEQKTQGFEAVIGIETHVQLSTVTKAFCSCPYSYGAQPNSTVCPTCMGHPGTLPVLNEKVVECAVKLGLALNCEISMTSKFDRKQYFYPDLPKGYQISQFDIPIAKKGHVDLDLPVEFGGGHRKFGITRVHMEEDAGKLLHSESSSYSQVDLNRAGVPLLEIVSEPDMRTGIEAAEYGAELQRIVRYLGVSNGNMQEGSLRCDVNVSIRPVGQSEFGTKVEIKNMNSFSAINRAIDYEISRQILLHKEGQADQIVQETRLWDESSQKTFTMRKKEGLADYRYFPEPDLPEVVLTSDYINEISKSMPELPEAKRRRYENMGLSMQDVLFLANDDNIGHFYDSTLEHGADAKLAANWIMGDIAAYLKDEKVSIDEIKLTPLELSELIASIKNGTISGKIGKEILAELIAKGGTVKGVIEEKDLVQIADPAAIEAMVDKVIADNPKQLEQYRAGKTKLQGFFAGQVMKASKGKANPVLLNKILGEKLNAN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: RSD_ECOL5
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_BURA4
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFIAAIVVGRIRLKLPHVAAQGWTAKDIDDMMFYGVLGTVLGGRLGYVLFYKADFYFSHPLDVFKVWEGGMSFHGGFLGVTLAMVLFAWQRKRHWLQVTDFVAPMVPAGLAAGRLGNFINGELWGRVTDPNAPWAMLFPGAMRDDAAWLSKHPALVEKWHLADVFMQYQMLPRHPSQLYEIALEGIALFFVLFFFSRKPRPLGAVSALFLIGYGLARFTVEFAREPDDFLGLLALGLSMGQWLSLPMILAGIALLVWGYRRRPVNAAA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STK31_HUMAN
Sequence: MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC
What are the official names of this protein?
Serine/threonine-protein kinase 31, Serine/threonine-protein kinase NYD-SPK, Sugen kinase 396, SgK396.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: GLT12_HUMAN
Sequence: MWGRTARRRCPRELRRGREALLVLLALLALAGLGSVLRAQRGAGAGAAEPGPPRTPRPGRREPVMPRPPVPANALGARGEAVRLQLQGEELRLQEESVRLHQINIYLSDRISLHRRLPERWNPLCKEKKYDYDNLPRTSVIIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSGLPKVRLIRANKREGLVRARLLGASAARGDVLTFLDCHCECHEGWLEPLLQRIHEEESAVVCPVIDVIDWNTFEYLGNSGEPQIGGFDWRLVFTWHTVPERERIRMQSPVDVIRSPTMAGGLFAVSKKYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGVLETHPCSHVGHVFPKQAPYSRNKALANSVRAAEVWMDEFKELYYHRNPRARLEPFGDVTERKQLRDKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQNKGLTDYCFDYNPPDENQIVGHQVILYLCHGMGQNQFFEYTSQKEIRYNTHQPEGCIAVEAGMDTLIMHLCEETAPENQKFILQEDGSLFHEQSKKCVQAARKESSDSFVPLLRDCTNSDHQKWFFKERML
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7.  Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2.  May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs.
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 12, Polypeptide GalNAc transferase 12, GalNAc-T12, pp-GaNTase 12, Protein-UDP acetylgalactosaminyltransferase 12, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RSGA_STRP3
Sequence: MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIYPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGVGKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_PROMT
Sequence: MTTVQLQKTNQPSIKASRGSYWITTFGCQMNKADSERMSGILEYMGYYPAEEELKADLVLYNTCTIRDSAEQKVYSYLGRQAIRKRSLPNLKIVVAGCLAQQEGESLLRRVPEIDLLMGPQHCNRLESLLNQVDSGQQVLATEEQFILEDITTPRRDSSICGWVNIIYGCNERCTYCVVPSVRGKEQSRTPEAIKSEVEDLAKSGYKEITLLGQNIDAYGRDFQSQNKEDSAQVTLSYLLKYIHDIEGIERIRFATSHPRYFTKELIDTCSELPKVCEHFHIPFQSGSNKILKNMGRGYTIESYKNIINYIKAKIPKAAISGDAIVAFPGESETDYEQTLSLIDEIKFDHVNTAAYSPRPNTPAATWPRQLNEDIKVKRLREINSLVENIAKERNQRYKNTSQEILIENINPKDSFQLMGRTRTNRLTFFPRSLKNGVENKLGELIKVKITDVRPFSLTAKLL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGLA_ASPAC
Sequence: MLKASLLSFVAFTAQVAHAAFGITTSSSAYVIDTNAPNQLKFTVSRSSCDITSIIHYGTELQYSSQGSHIGSGLGSATVTATQSGDYIKVTCVTDTLTQYMVVHNGDPIIHMATYITAEPSIGELRFIARLNSDLLPNEEPFGDVSTTADGTAIEGSDVFLVGSETRSKFYSSERFIDDQRHCIAGDAHRVCMILNQYESSSGGPFHRDINSNNGGSYNALYWYMNSGHVQTESYRMGLHGPYSMYFSRSGTPSTSIDTSFFADLDIKGYVAASGRGKVAGTASGADSSMDWVVHWYNDAAQYWTYTSSSGSFTSPAMKPGTYTMVYYQGEYAVATSSVTVSAGSTTTKNISGSVKTGTTIFKIGEWDGQPTGFRNAANQLRMHPSDSRMSSWGPLTYTVGSSALTDFPMAVFKSVNNPVTIKFTATSAQTGAATLRIGTTLSFAGGRPQATINSYTGSAPAAPTNLDSRGVTRGAYRGLGEVYDVSIPSGTIVAGTNTITINVISGSSGDTYLSPNFIFDCVELFQ
What is the function of this protein?
Pectinolytic enzyme that has a positive effect in the apple hot-mash liquefaction process.  This endolyase hydrolyzes the alpha-L-rhamnopyranosyl-(1,4)-alpha-D-galacturonopyranosyl glycosidic linkage by beta-elimination, thereby generating oligosaccharides terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.
What are the official names of this protein?
Rhamnogalacturonate lyase A, Rhamnogalacturonan lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHLB_XYLFT
Sequence: MSDKPLTNLNFSSFDLHPALLTGLTRAGFTLCTPIQALTLPVALAGRDIAGQAQTGTGKTLAFLVVVVNRLLSSPGLVNRNPEDPRALILAPTRELAIQIYNDAVKFGGNLGLRFALIYGGVDYDRQREMLRKGADVVIATPGRLIDYLKQHEVVSLRVCEICVLDEADRMFDLGFIKDIRFILRRLPERCSRQTLLFSATLSHRVLELAYEYMNEPEKLVAETESVTTTRVRQRIYFPAEEEKIPLLLGLLSRNEGMRTMVFVNTKVFVEGVARALDEAGYRVGVLSGDVPQRKRETLLNRFQKGQLEILVATDVAARGLHIDGVNYVYNYDLPFDAEDYVHRIGRTARLGADGDAISFACERYAMSLPDIEAYIEQKIPVAAVTAELLAPLSRPGRASNGNGDTVGDISPHSRDVLVAQEWRRGKPRGSPGERDGRIRVCKGTRSDGGGGRRRTKFRLETERDSSVDGAVTPVFGVSTGIVSAPGKEVGRNIGLRRRSRSMDSGESGHVVATADQVAAKSGSQPSLLGRIGRRIRSLLSMF
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_NITHX
Sequence: MRLFVGLGNPGTKYQGNRHNIGFMVVDEIARRHGFAPWRRRFQGEASEGALDQERVVLLKPATYMNESGNAVQDAARFFKLTEGDVVVFHDEIELPPAKVRVKVGGGIAGHNGLRSISAHIGNEYRRVRLGVGHPGVKERVHAHVLNDFAKSERPWVEALVDVVAENAALLVTARDSAFQNKVHLAMQAKGFVEKDAKGDNGGK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_NITEU
Sequence: MDKQNVPVITLDGPSASGKGTIARLVSQALGFHYLDSGALYRLVALAAMKRNTDVSDEHSMVDIARHLNVSFRDSSIWLEGKDVSDEVRAEACGEYASRIAQYSALRVELLGYQRDFRKSPGLVTDGRDMGSVIFPDATLKIYLTASEEERALRRHKQLMEKGINASIADLIQALRARDERDSSRSTSPLQQCEDACLLDTTGLSIDQVVSRVLNMYAEARKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOGH_RHOFA
Sequence: MNLRPMPATTVSAQARPTPKSVTVFCGAMPGRGTKYGQLAEGMGRAIARSKLRLVYGGARVGLMGTLANAALDSGGTVVGVIPESFTAIPEAAHHGLTELHVVHDMHQRKALMAELGDAFIALPGGVGTAEEFFEVLTWSHLGLHNKPCVLLNDNEYYRPLLSYIEHAAVEGFITPATRSRVIVCKDIEGAIAAIRSP
What is the function of this protein?
Catalyzes the hydrolytic removal of ribose 5'-monophosphate from nitrogen N6-modified adenosines, the final step of bioactive cytokinin synthesis.
What are the official names of this protein?
Cytokinin riboside 5'-monophosphate phosphoribohydrolase, LOG family protein ORF6 in fasciation locus.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: CVC1_HHV6Z
Sequence: METHLYYDTLYQYQGGVYPAHICLPTDAYLPMRVDCIESLYFRCVFFKNGMHYTEWSKLKFTVISREIKFKDVLKNADFDELFTGLVVMTIPIPIVDFHFDIDSVILKLVYPQLVHREIVLRLYDLICIRPSSDRPSEVSAKNIGIDFYQLTSQGNKQTPDEEKRCLFFQQGPLEPPSTVRGLKAAGNAKPMQFPAHVNEKMTESFLSDSWFEQKVRCKKILDFTQTYRVVVCWYELSFSREMQIENNLLSASQLKRVNAADFWDRTDRYLRDIGSRVLTHIVKTLQIHNRQFKQKFNCNFPVNFSFEHLLSFMQLGKDFWILNLTLDSCIIKAIICFLGFRNGRKSFLAQDEVWGDLIDCSKGSVIYGEKIQWILDSTNNLYSTRREKQNKSWELYVDCCALYVSEKLELDFVLPGGFAITGKFALTDGDIDFFNWRFGLS
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: CTDS1_HUMAN
Sequence: MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
What is the function of this protein?
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.  Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.  Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
What are the official names of this protein?
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1.
Protein: ATPA_ECOUT
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNFH_MAGSA
Sequence: MKIGVVYALPSRQSWLSIDVPEGTTVKEAIQKSGILNQFPEIDLETQKVGIFGKAAALDAVVEEGARIEIYRPITVDPKTVKRRAAPEAPAAGGTES
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: ACE2_BOVIN
Sequence: MTGSFWLLLSLVAVTAAQSTTEEQAKTFLEKFNHEAEDLSYQSSLASWNYNTNITDENVQKMNEARAKWSAFYEEQSRMAKTYSLEEIQNLTLKRQLKALQHSGTSALSAEKSKRLNTILNKMSTIYSTGKVLDPNTQECLALEPGLDDIMENSRDYNRRLWAWEGWRAEVGKQLRPLYEEYVVLENEMARANNYEDYGDYWRGDYEVTGAGDYDYSRDQLMKDVERTFAEIKPLYEQLHAYVRAKLMHTYPSYISPTGCLPAHLLGDMWGRFWTNLYSLTVPFEHKPSIDVTEKMENQSWDAERIFKEAEKFFVSISLPYMTQGFWDNSMLTEPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPYLLRNGANEGFHEAVGEIMSLSAATPHYLKALGLLAPDFHEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKQQWMEKWWEMKREIVGVVEPLPHDETYCDPACLFHVAEDYSFIRYYTRTIYQFQFHEALCKTAKHEGALFKCDISNSTEAGQRLLQMLRLGKSEPWTLALENIVGIKTMDVKPLLNYFEPLFTWLKEQNRNSFVGWSTEWTPYSDQSIKVRISLKSALGENAYEWNDNEMYLFQSSVAYAMRKYFSEARNETVLFGEDNVWVSDKKPRISFKFFVTSPNNVSDIIPRTEVENAIRLSRDRINDVFQLDDNSLEFLGIQPTLGPPYEPPVTIWLIIFGVVMGVVVIGIVVLIFTGIRNRRKKNQASSEENPYGSVDLNKGENNSGFQNIDDVQTSL
What is the function of this protein?
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis.  Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II.  Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin.  Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A.  Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity.
What are the official names of this protein?
Angiotensin-converting enzyme 2, ACE-related carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
[Processed angiotensin-converting enzyme 2]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, cilium. Apical cell membrane. Note=Detected in both cell membrane and cytoplasm in neurons.
Protein: RL3_PYRAB
Sequence: MGKVHRPRRGSLAFSPRKRAKSIVPRIRSWPKETEVRMLGFAGYKAGMTHILMIDDEPGLTNGKEIFMPVTIIETPPLRVFGIRAYRQGYLGLETATEVIVPDFELDNYVSKKAKGRKFTFYQLLKRRIATLPKNYTKDDFEQKLGNLEDMIKEGEIVEVRALVATQPWVIKLKKKPEVMEYAIGGTSVEEKFNYIKEKLGKELRVGEVLKEGELLDVIAVTKGKGTQGPVKRWGIKLRAHKDSKGRRKVGSIGPWHPARVMWTVPMAGQMGFHHRTELNKRLIAIGENGKLVIDGNEIEITPKGGFPHYGIVRSDFMMIAGSVPGAIKRIIRVRPAIRPPKKKPPVQRPQITYVSVESKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GRPE_METBF
Sequence: MKIFNKDGNKNSKEDTKAGAENSEAQNSGSSAEEVNKARENPEEASASSEAEKSPEVKCQEEKQVLMEKYYRLAADFDNFKKRTARQMEENRKAVLEQVLLDFVEVTDNFDRALKSAKTAEDMSSIVSGIEQLSRQFFSILEKYGLEKIESEKASEFDPHRHEAVHHIETSEVPDNTIVDVYKTGYALNSKVIRPAMVSVARNPDEAEK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECG_HAEIN
Sequence: MSLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQYFTIEGIVQTCEVAFGRRPILSVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVKRGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQNSLRKLTDQALALLDKVQIAEILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVRLGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGSGKTLVAALAALTAIDNGKQVALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQHRFGVHQRLMLREKGEKAGFYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACVNEKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFKNAELDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKPPLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQTGIAELRVANLMRDRKMIPTVQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.