PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_CHLPD
Sequence: MSIRTEKVASLLQQELGMILEKEFPRGGPILTVVEVKVTADLGIAKVYVSVIGSAKEQADTIEYLQQEKKNIRKILSSKIRHHFRRIPELEFYQDRLYEKADRIEQLLKEVRKEQE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_HAEDU
Sequence: MARQYAVWGNPIAHSKSPYIHQLFAQQSNRRIEYAAKLGDKIAFEKQLVQFFTDGANGVNITSPFKARAFRLADVCSESCLLAGAANTLKRLDDGRLFADNTDGKGFCADLARLEWLIPEQRVLILGAGGVTKGVLLPLLLAKQKVTLSNRTHIKAVELAQQFAKYGDIQAVSLSEIVQHPPFDLIINATSLGLQGGYIALPNHLFEKSAVYDMEYASNMCTPFLNYVRTQGVTRYQDGLGMLVNQAAFSFQLWEGELPKVENVLKQLRAEMGYVK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YR050_MIMIV
Sequence: MTMFIVSWTGLPRHFLKKKGGMNLDHGILKDEYIVIEDINICVFAPDKINALLNAIQHFCNLDENEDYLLSKNIDTTLEILKKMNPTVTALNDGVVFQFKEASSIMYKGFNIE
What are the official names of this protein?
Uncharacterized protein R50.
Protein: PROB_CAMJE
Sequence: MKRIVVKVGSHVISEENTLSFERLKNLVAFLAKLMEKYEVILVTSAAISAGHTKLDIDRKNLINKQVLAAIGQPFLISVYNELLAKFNKLGGQILLTGKDFDSRKATKHAKNAIDMMINLGILPIINENDATAIEEIVFGDNDSLSAYATHFFDADLLVILSDIDGFYDKNPSEFSDAKRLEKITHIKEEWLQATIKTGSEHGTGGIVTKLKAAKFLLEHNKKMFLASGFDLSVAKTFLLEDKQIGGTLFE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPAD_ASPNC
Sequence: MSTDSIEVAIIGAGITGITLALGLLSRGIPVRVYERARDFHEIGAGIGFTPNAEWAMKVVDPRIQAAFKRVATPNASDWFQWVDGFNESGTDPRETEEQLLFKIYLGERGFEGCHRADFLGELARLLPEGVVTFQKALDTVEPAADNSLGQLLRFQDGTTATAHAVIGCDGIRSRVRQILLGEDHPAASAHYSHKYAARGLIPMDRAREALGEDKVATRFMHLGPDAHALTFPVSHGSLLNVVAFVTDPNPWPYADRWTAQGPKEDVTAAFSRFGPTMRTIIDLLPDPIDQWAVFDTYDHPPNTYSRGAVCIAGDAAHAAAPHHGAGAGCGVEDAAVLCAVLDMAAKRVDTAKDGTEGKAALITTAFETYDAVRRERAQWLVESSRVIGNLYEWQDKEVGSDASRCHDEVYWRSHRIWDYDIDAMMRETAEVFEARVAGVAKN
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of nigerpyrone and its derivatives carbonarone A and pestalamide A (PubMed:30384904).  The biosynthesis pathway begins with the polyketide assembly by epaA to form phenylacetyl triketide precursor from successive condensation of two malonyl-CoA, presumably with one phenylacetyl-CoA starter unit produced by the phenylacetyl-CoA ligase epaB (PubMed:30384904).  For the nigerpyrone biosynthesis, the reactive polyketide chain is released as an aldehyde through the R-domain.  A nonenzymatic cyclization and dehydration may create nigerpyrone (PubMed:30384904).  For the biosynthesis of carbonarone A and pestalamide A, an extra methyl group is added through the C-methyltransferase domain.  Several further steps involving the dehydrogenase orf1, the cytochrome P450 monooxygenase orf2 and the FAD-dependent monooxygenase orf3 are required to form a carbonarone A precursor which is converted to carbonarone A via cyclization (PubMed:30384904).  The O-acetyltransferase epaC could catalyze the transfer of 2-methylsuccinyl-CoA, a common intermediate in the ethylmalonyl-CoA pathway, to generate the final product pestalamide A (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase orf3, Pestalamide A biosynthesis cluster protein orf3.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ISPG_ANOFW
Sequence: MSEIIHRSKTRPVRVGNITIGGNNEVVIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVACPDERAADAIAEIKKRINIPLVVDIHFDYRLALKAIENGADKIRINPGNIGKREKVEAVVKAAKERGVPIRIGVNAGSLEKRILDKYGYPTADGMVESALHHIRILEDLDFQDIIVSLKASDVRLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILSKGIGNTVRVSLSADPVEEVKVARELLKAFGLAANAATLISCPTCGRIEIDLISIANEIEEYIAQIKAPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRHGKIVRKVPEETMVEELKKEIDKLAEEYASKGKQK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RSXB_SALTY
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKIAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: TRIC_VIOAR
Sequence: MKTMASFVLVLVAAFALPAAFASLETKDVITRAAYEKLVESGAIQGITMTKTIISNPILEEALVAHFNRKLGGGTIFDCGESCFLGTCYTKGCSCGEWKLCYGTNSLPESNNEKAMVASLEKDVITRAAYENLVNSGAIQGITMTKTIISNPILEEALVSHFNRKLGGGTIFDCGESCFLGTCYTKGCSCGEWKLCYGENSLAI
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has a weak hemolytic activity.
What are the official names of this protein?
Pro-tricyclons.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: SNX14_MOUSE
Sequence: MWLRRRGLGVPSASASEGGTSSPAWTEMGSWVRTICGRLKQRLRLDVGREICRQYPLFCFLLLCLSVASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVSSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFNRSTQKRGESFGISRIGSKIKGVFKSTTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEATSMTSWM
What is the function of this protein?
Plays a role in maintaining normal neuronal excitability and synaptic transmission.  May be involved in several stages of intracellular trafficking (PubMed:24859318).  Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes.  Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes.  Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity).
What are the official names of this protein?
Sorting nexin-14.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: PRMA_CAMJJ
Sequence: MQKKYYELFFIVEERYKNLFLDFAFDLGIEAIEEKDNGVYIRSHESLEDLSWALEIFAQKLTTTFNLNHKIISNLSLVEKENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKINPALAFGSGHHESTYSCVKFLQKFSKSKLRALDLGCGSGILGIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFYKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILILSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BACTN
Sequence: MKVDVLLGLQWGDEGKGKVVDVLTPKYDVVARFQGGPNAGHTLEFEGQKYVLRSIPSGIFQGDKVNIIGNGVVLDPALFKAEAEALEASGHPLKERLHISKKAHLILPTHRILDAAYEAAKGDAKVGTTGKGIGPTYTDKVSRNGVRVGDILHNFEQKYGAAKARHEQILKSLNYEYDLTELEKAWMEGIEYLKQFHFVDSEHEVNNYLKDGKSVLCEGAQGTMLDIDFGSYPFVTSSNTVCAGACTGLGVAPNRIGEVFGIFKAYCTRVGAGPFPTELFDETGDKMCTLGHEFGSVTGRKRRCGWIDLVALKYSVMINGVTKLIMMKSDVLDTFDTIKACVAYKVDGEEIDYFPYDITEGVEPVYAELPGWKTDMTKMQSEDEFPEEFNAYLTFLEEQLGVEIKIVSVGPDRAQTIERYTEE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STUST
Sequence: MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEVVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10, Heat shock protein 10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: HIS1_TRIV2
Sequence: MLTVALPKGELLKNSIRLLKSVGLDFSAFLDSGNRQLQITDASGRAKGLLVRGQDVPVYVEYGQAQIGIIGYDVLREKQPQVAHLVDLQFGYCRMSVAVKASSPYKSPLDLPAHSRVASKYVNSAREFFQGLDLPVEIVPLYGSVELGPITGMSEAIVDIVSTGRTLKENGLVEITTLYESTARLIAHPLSYRLNTGNLHQLVEQLREGVLSELPILT
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB5_ANADE
Sequence: MPHGPGTSARPVRVLVVDDSALVRETLAAVLASDPGIEVIGAAGDPYAAVERMRRQAPDVITLDIEMPRMDGLTFLRKLMAQHPIPVVICSSLATAGAEPALRALECGAVEVVAKPRLGTRRFLEESRVRLCDAVKAAARAGPGRPRASAPLVQAKLTADAVLARPRSDAVLQTTERVVVVGASTGGTEALRELLAALPGDAPGLVIVQHMPEVFTAAFARRLDGLCAVAVKEAADGDAVVPGRALIAPGNRHTLLRRSGARYHVEVRDGPLVCRHRPSVDVLFRSAARYAGRNAVGVIMTGMGDDGARGLAELKRSGADTIAQDEATSVVFGMPREAIRLGAADRVLPLPAIPPELLRLCR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 5.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKSF_METJA
Sequence: MMKVCVIEGDGIGKEVIPEAIKILNELGEFEIIKGEAGLECLKKYGNALPEDTIEKAKEADIILFGAITSPKPGEVKNYKSPIITLRKMFHLYANVRPINNFGIGQLIGKIADYEFLNAKNIDIVIIRENTEDLYVGRERLENDTAIAERVITRKGSERIIRFAFEYAIKNNRKKVSCIHKANVLRITDGLFLEVFNEIKKHYNIEADDYLVDSTAMNLIKHPEKFDVIVTTNMFGDILSDEASALIGGLGLAPSANIGDDKALFEPVHGSAPDIAGKGIANPMASILSIAMLFDYIGEKEKGDLIREAVKYCLINKKVTPDLGGDLKTKDVGDEILNYIRKKLKGY
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and decarboxylation of (2R,3S)-homoisocitrate, (2R,3S)-homo(2)-isocitrate and (2R,3S)-homo(3)-isocitrate, into 2-oxoadipate, 2-oxopimelate (2-oxoheptanedioate), and 2-oxosuberate, respectively.  All these substrates are intermediates in the biosynthesis of biotin and of 7-mercaptoheptanoate, a moiety of coenzyme B in methanoarchaea (PubMed:18765671, PubMed:10940051).  Is also able to produce 2-oxoazelate from (2R,3S)-homo(4)-isocitrate in vitro, but this substrate is probably not physiologically relevant (PubMed:18765671).  Is unable to use any isomer of isocitrate or isopropylmalate as a substrate, and NADP as an oxidant (PubMed:10940051).
What are the official names of this protein?
Homoisocitrate dehydrogenase, HICDH, Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase, Isohomocitrate dehydrogenase, IHDH, NAD-dependent threo-isohomocitrate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: PHNL_ECOLI
Sequence: MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVIPRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNIARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADRLHPMGASS
What is the function of this protein?
Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.
What are the official names of this protein?
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL, RPnTP synthase subunit PhnL.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: CBID_BRUA4
Sequence: MNDETAPTNKSQEKAELRRGWTTGACATAATKAALTALITGEFPDPVGIILPKGEVPYFQLAYEGLGDGYAMAGIVKDAGDDPDVTHGATIISTVFPAPPGTGVVFRAGEGVGTVTRPGLQIPPGEAAINPVPRRMMTEICEQICAEYGLPADIVITISVPGGEEIAKKTWNPRLGIVGGISILGTTGVVHPFSCSAWIHSIHRGIDVARAAGQKHVLGATGSTSEDAAQALYDLPDFAILDMGDFAGGVLKYLREHPIDKLTIAGGFAKLTKLAQGALDLHSSRSQVDKSFLWTLAEKAGAPESMKDQILFANTALEVLELTQSIGLDMATPIALKAKETALETLRGAPVAVEIIVTDRSGNILARV
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: O52A5_HUMAN
Sequence: MPTFNGSVFMPSAFILIGIPGLESVQCWIGIPFSAMYLIGVIGNSLILVIIKYENSLHIPMYIFLAMLAATDIALNTCILPKMLGIFWFHLPEISFDACLFQMWLIHSFQAIESGILLAMALDRYVAICIPLRHATIFSQQFLTHIGLGVTLRAAILIIPSLGLIKCCLKHYRTTVISHSYCEHMAIVKLATEDIRVNKIYGLFVAFAILGFDIIFITLSYVQIFITVFQLPQKEARFKAFNTCIAHICVFLQFYLLAFFSFFTHRFGSHIPPYIHILLSNLYLLVPPFLNPIVYGVKTKQIRDHIVKVFFFKKVT
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52A5, Odorant receptor HOR3'beta5, Olfactory receptor OR11-33.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADK_NITEU
Sequence: MDSALFKTIALIGKHKNPDIVIPLLSLAEYLTDRGISVVLDSLTAAHISNSRYPILTLEEIGKQADLAIVLGGDGTMLNIARALVPFSVPLIGINQGRLGFLTDLTADTMHETLNDMLAGQFVVENRMLLTVEVTRNGESVFKELAFNDVVLHRGISSGMIELEVHINGEYVYSLRSDGLIIATPTGSTAYALSSGGPILHPGLNLMTLVPICPHTLSNRPIVIGADATIEIKVHFTTEIKIYTDSHSWFDLSEHDRVFIQRCPETIKLLHPVHHSYYRMLREKLGWSGILQKNSR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SYNJA
Sequence: MARKLSKRMQALREKVKPIAYPPAEALALMKETATAKFDEAAEVHIRLGIDPKYADQQLRTTVVLPRGTGQEIRVAVIARGEKVTEAQNAGADRVGFEDLIEEIGKGVIDFDLLIATPDVMPQVAKLGRLLGPRGLMPSPKGGTVTMDLAQAIKEFKAGKLEYRADKTGIVHLIFGKCKFPVEALLENLKAVQESIDRNRPPGAKGKYWRALHVCATMGPSIEVDINALRELKLVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: IFNT_CAPHI
Sequence: MAFVLSLLMALVLVSYGPGGSLGCYLSRRLMLDARENLRLLDRMNRLSPHSCQQDRKDFGLPQEMVEGDQLQKDQASCVLYEMLQQSFNLFYTEHSSAAWDTTLLDQLCTGLQQQLDHLDTCRGQVMGEKDSELGNMDPIVTVKKYFQGIYYYLQEKGYSDCAWETVRVEMMRALTASTTLQKRLTKTGGDLNSP
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible.
What are the official names of this protein?
Interferon tau, IFN-tau, Antiluteolysin, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: ALF1_STAAE
Sequence: MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVESKYTADYLADKGVVPFLKVDKGLAEEQNGVQLMKPIDNLDNLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFEVAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTEPNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNAELIASFSRALASDLRADQSKEEFDKALGDAVESIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: GLK_HELPY
Sequence: MPKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLKLHPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQENDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISECALNGDYPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVLKKTPGLDGAGIALENYLLHDKI
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_BACTN
Sequence: MAVRKLKPTTPGQRHKIIGTFEEITASVPEKSLVYGKKSSGGRNNEGKMTMRYIGGGHRKVIRIVDFKRNKDGVPAVVKTIEYDPNRSARIALLYYADGEKRYIIAPNGLQVGATLMSGETAAPEIGNTLPLQNIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSREGKYCVIKLPSGEVRQILSTCKATIGSVGNSDHGLERSGKAGRSRWQGRRPRNRGVVMNPVDHPMGGGEGRSSGGHPRSRKGLYAKGLKTRAPKKQSSKYIIERRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PANC_PARPJ
Sequence: MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTMEADIEKLQKENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPGFFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQFALPTDIIAAETVRDTDGLALSSRNRYLQAAERAEAPKLAAELNRVRDAVLSGERDFAKVEQAAMAALAARGWQPDYIAVRKRSDLLPPGPQDANAQLVVLAAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_XANC5
Sequence: MTAKTLYDKLWDLHEVTRRDDGSSLIYIDRHILHEVTSPQAFEGLRLAGRKPWRIDANIATPDHNVPTTRAERQGGLESISDEVSRLQVQTLDENCDDFGILEFKMNDTRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLIAKKMKNMQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRAASMEGRMTICNMAIEAGARVGMVAVDEKTIAYVKGRPFAPKGAHWDAAVALWSTLVSDPDAHFDTVVELRAEDIKPQVSWGTSPEMVLAIDQHVPDPAAEQDPTKRDSIERALKYMGLTANQPITAIRLDRVFIGSCTNSRIEDLRAAAAVAKGRKVASTIKQALVVPGSGLVKAQAEAEGLDKVFLDAGFEWREPGCSMCLAMNPDKLGSGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVSGHFVDVRELGDSGVGIRDS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GLMM_CHLT2
Sequence: MTRDVSQLFGTDGVRGRANFEPMTVETSVLLGKAIAGVLLEKHAGKHRVVVGKDTRLSGYMFENALIAGLTSMGIETLMLGPIPTPGVAFITRAYRADAGIMISASHNPYRDNGIKIFSSDGFKIGQAVEERIEAMVASKDFGKLPDDHAVGKNKRVKDATGRYIEYAKATFPKGRTLKGLRIVLDCAHGATYRVAPSVFEELDAEVICYGCEPSGCNINAGCGALWPSTIQKAVIEHKADVGIALDGDGDRLIMVDEKGHIVDGDMLLSICASDLKRRQALPDNRVVATVMTNFGVLRYLESLGIQVTISPVGDRHVLQHMLENQAVLGGEQSGHMIFLDYNTTGDGIVSALQVLRIMIESESTLSDLTACIVKSPQALINVPVTKKVPLESLANVQGVLKEVKEVLGDSGRILLRYSGTENICRVMVEGTKKHQVDSLAKTIVDVVEAEIGAGISE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HBE_OTOCR
Sequence: MVHFTAEEKAIIMSLWGKVNIEEAGGEALGRLLVVYPWTQRFFETFGNLSSASAIMGNPKVKAHGKKVLTSFGEAVKNMDNLKGAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFGKEFTPDVQAAWQKLVSGVATALAHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.