PharMolix/UniProtQA huggingface dataset:
Protein: PP14B_PIG
Sequence: MADSGPAGGAALAAPAPGPGSGGAGPRVYFQSPPGAAGEGPGGADDEGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEIPELEIDVDELLDMESDDTRAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK
What is the function of this protein?
Inhibitor of PPP1CA.  Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14B, Phosphatase holoenzyme inhibitor 1, PHI-1, Ubiquitous PKC-potentiated PP1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAGP_SALTI
Sequence: MYVAMIIRKYFLIIALLVMPWLAIPSVSAADKGWFNTFTDNVAETWRQPEYYDLYVPAITWHARFAYDKEKTDRYNERPWGVGFGQSRWDDKGNWHGLYMMAFKDSFNKWEPIGGYGWEKTWRPLEDDNFRLGLGFTAGVTARDNWNYIPIPVLLPLASIGYGPATFQMTYIPGSYNNGNVYFAWMRFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ATG28_PICPA
Sequence: MICLFGNCNCQTGIFGLYDYVSFLYHSPSSCRVRLVLSLPASPNHMEEQSPKFESSFPRRTSEGPVDDVGKSPPASFYRELLANKAQQPQLSEDEEDHNPKDFLFKEDSEDELLIPDSENHNSSSTSPRKFKVENIRWGSDTLNGSILPLNSQGSNLQSLLSNVGELEHLLSKDVAKHSKYLKEQSSKVEKARANIVTNLTRLSLVLSSIFNTYQAKAQDKQAILDKIEEWEDEKKSLLDDMKEVLSTDDNADGETHKFLELASESINVENEIEALETRLKQLKIKQRTLKNECFQSQGIIESRLSNFVQAVEKIEMRERKSIEQVVQQLSENQLGYWNDNLALEVMNGLTINPGDISLVEEYEPVDILKQVESLEKPTIAADYHLPKNTNKQASRFTRQLLEFNYKCQPKLNVYPVVGLITKELKEDSAKEQEYKHRYDQVTHTLSALKDSFALIYHTEQQLQSITQSTQDLKDFQSLMNQMVESLLKTHSEADQYNLYLAKDVLAQEISIIHQALNKLNQSTEYSSVESDNVKNHDGLLFQTFSKAQERTKLPSIKSATSIRYAPSLYNSLSPTSTSKTTAKGEVNYDAGINKYTKVKEVLRSGKGNKDE
What is the function of this protein?
Required for autophagic degradation of peroxisomes called pexophagy, but not essential for general autophagy.  Involved in resistance to elevated pH.
What are the official names of this protein?
Autophagy-related protein 28.
What is the protein family that this protein belongs to?
Belongs to the ATG28 family.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Concentration increases at the vacuolar and cytoplasmic vesicular membranes during the course of pexophagy.
Protein: NUOI_PARDP
Sequence: MAFDFARATKYFLMWDFIKGFGLGMRYFVSPKPTLNYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIDAEPREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEYATETREELFYDKQKLLANGERWEAEIARNLQLDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit 9, NADH dehydrogenase I subunit I, NADH-quinone oxidoreductase subunit 9, NQO9, NDH-1 subunit 9, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL2_STRPI
Sequence: MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RNMC1_MOMCH
Sequence: FDSFWFVQQWPPAVCSFQKSGSCPGSGLRTFTIHGLWPQGSGTSLTNCPQGSPFDITKISHLQSQLNTLWPNVLRANNQQFWSHEWTKHGTCSESTFNQAAYFKLAVDMRNNYDIIGALRPHAAGPNGRTKSRQAIKGFLKAKFGKFPGLRCRTDPQTKVSYLVQVVACFAQDGSTLIDCTRDTCGANFIF
What is the function of this protein?
Ribonuclease cleaving preferentially the 5'-side of uridine.
What are the official names of this protein?
Ribonuclease MC, RNase MC, RNase MC1.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: SNP29_HUMAN
Sequence: MSAYPKSYNPFDDDGEDEGARPAPWRDARDLPDGPDAPADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDLKISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNLRKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKVRQL
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.  SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane.  Also plays a role in ciliogenesis by regulating membrane fusions.
What are the official names of this protein?
Synaptosomal-associated protein 29, SNAP-29, Soluble 29 kDa NSF attachment protein, Vesicle-membrane fusion protein SNAP-29.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Localizes to the ciliary pocket from where the cilium protrudes.
Protein: SAUV_PHYSA
Sequence: QGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI
What is the function of this protein?
Hypotensive and diuretic peptide.
What are the official names of this protein?
Sauvagin, Sauvagine, SVG.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_SODGM
Sequence: MLQPKRTKFRKMHKGRNRGLAVGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRIFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GLO2M_ARATH
Sequence: MPVISKASSTTTNSSIPSCSRIGGQLCVWPGLRQLCLRKSLLYGVMWLLSMPLKTLRGARKTLKITHFCSISNMPSSLKIELVPCSKDNYAYLLHDEDTGTVGVVDPSEAAPVIEALSRKNWNLTYILNTHHHDDHIGGNAELKERYGAKVIGSAVDKDRIPGIDILLKDSDKWMFAGHEVRILDTPGHTQGHISFYFPGSATIFTGDLIYSLSCGTLSEGTPEQMLSSLQKIVSLPDDTNIYCGRENTAGNLKFALSVEPKNETLQSYATRVAHLRSQGLPSIPTTVKVEKACNPFLRISSKDIRKSLSIPDSATEAEALRRIQRARDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase 1, mitochondrial, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS14Z_STAA9
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: TPIS_LEVBA
Sequence: MRIPLIAGNWKMNKSVTEARQFIDAVQGQLPQADVIETAVAAPALFLQTMLDANAEGTLRVAAETCYYEDEGAYTGETSPRALHEMGIPYTIVGHSERRRYFNETDDVINRKVQAVFRNGMTPILCCDETMGRRTAGEKIHWVVNQVSAALKGVSAEDAAKIVVAYEPSWAIGSGTSASSDQAEEGCYLIRQTLADIYSDDLANGVRVLYGGSVKPDNIAGLMAKSNVDGVLAGGSSLDETSFIQLANYQNL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAA_RHIME
Sequence: MTSILTNNSAMAALSTLRSISSSMEDTQSRISSGLRVGSASDNAAYWSIATTMRSDNQALSAVQDALGLGAAKVDTAYSGMESAIEVVKEIKAKLVAATEDGVDKAKIQEEITQLKDQLTSIAEAASFSGENWLQADLSGGPVTKSVVGGFVRDSSGAVSVKKVDYSLNTDTVLFDTTGNTGILDKVYNVSQASVTLPVNVNGTTSEYTVGAYNVDDLIDASATFDGDYANVGAGALAGDYVKVQGSWVKAVDVAATGQEVVYDDGTTKWGVDTTVTGAPATNVAAPASIATIDITIAAQAGNLDALIAGVDEALTDMTSAAASLGSISSRIDLQSDFVNKLSDSIDSGVGRLVDADMNEESTRLKALQTQQQLAIQALSIANSDSQNVLSLFR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Homomer of FlaA is able to form a functional filament.
What are the official names of this protein?
Flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: TRUA_STRU0
Sequence: MTRYKAIISYDGSQFQGFQRQSHARSVQEEIEKTLTKLTNGKEIKVHGAGRTDSGVHAYGQVLHFDLDQDRDLEKLRFALDTQSPEDIDFISVEKVSDDFHSRYTKHLKTYEFIVDIGRPKNPMMRHYATHFPYPLDLDNIQLAIKDLIGTHDFTGFTASGATIENKVRTIIDASVRYEEDKNFLIFTFTGNGFLYKQVRNMVGTLLKIGNNRMPVDQIKTILEKKDRQLAGPTPAGNGLYLKEIIYEDK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ILVC_RHOJR
Sequence: MAVEMFYDDDADLSIIQGRKVAVIGYGSQGHAHSLSLRDSGVDVRIGLKEGSKSRAKAEEQGLTVGTPAEVSEWADVIMVLAPDTAQASIFTNDIEPNLKDGDALFFGHGLNIHFDLIKAPEFVTVGMVAPKGPGHLVRRQFVDGKGVPALIAIDQDPKGEGQALALSYAKGIGGTRAGVIKTTFKEETETDLFGEQAVLCGGTEELVKTGFEVMVEAGYAPEMAYFEVLHELKLIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKERMKAILADIQSGEFTRRLVANVENGNTELEGLRKANAEHPIEVTGKKLRDLMSWVDRPITETA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CRTP_STAA8
Sequence: MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress (PubMed:15933032, PubMed:22535955).  Catalyzes the oxidation of the terminal methyl side group of 4,4'-diaponeurosporene to form 4,4'-diaponeurosporen-4-al (PubMed:15933032, PubMed:22535955).
What are the official names of this protein?
4,4'-diaponeurosporene oxygenase, 4,4'-diaponeurosporene oxidase, Carotenoid oxidase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtP subfamily.
Protein: ASNA_ECOHS
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC24_USTMA
Sequence: MDGATESGAASSPVVVFKRKRGRASQGTSSTLTNVATSSQAGPSGASRAHSDSGSSRSDSESGSTVVIKKKRRSANPLVQSTGRVYRKLKLSGSLDGEKENSVDADESGDAGLTSSSIASSSLQKMREDATRNSDWDLDTAGTLKETGVTSNSDGLYRGAKSYASFTRTRDDGCSSKMRSRGPIRQTTTVRTTSLIDYQPDVCKDYKETGYCGFGDTCKFLHDRSDYLAGWQLDVLPNSSSRTRENMLSDPEDSDTEDDIPFACLICRKAFTDPVVTRCAHYFCSSCAIKRFAKNSKCFACGQQTGGLFNSAKKVLERMDKLKQQKAQLRREKHEWLQDPQPTHQLATAGDSDVD
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC24.
What is the protein family that this protein belongs to?
Belongs to the CWC24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_XANP2
Sequence: MSRRCDLTGKGVLSGHTVSHSNHKTKRRFLPNLCNVTLESETLKRTIRLRVSANALKSVDHRGGLDAFLKKARDEELSPRALDFKRLIAKAAAEAASTAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PTGA_BUCAP
Sequence: MSFFSGFFNKKKSKYSKKIDILAPLSGDIINIEDVPDVVFSKKIVGDGIAINPTGNKILAPINGTIGKILNSMHAFSIISEEGVELFVHFGIDTVKLRGEGFKQIAQDNQKVKIGDTIILFDLNLLKEKARSILTPVVISNIEKFKNIEKSSGTIIAGKTIIMSLYN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIIA component, EIIA-Glc, EIII-Glc, Glucose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_MESVI
Sequence: MTEPNPNKQEVELNRTSLYWGLLLIFVLAILFSSYIFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL6_SHIDS
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ACY1_PIG
Sequence: MASKGREGEHPSVTLFRQYLRIRTVQPEPDYGAAVAFLEERARQLGLGCQKVEVVPGHVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEGFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKVEGHHFPRTIHMTFVPDEEVGGHQGMELFVKRPEFQALRAGFALDEGLASPTDAFTVFYSERSPWWLRVTSTGKPGHGSRFIEDTAAEKLHKVINSILAFREKEKQRLQSNQLKPGAVTSVNLTMLEGGVAYNVVPATMSACFDFRVAPDVDLKAFEEQLQSWCQAAGEGVTFEFVQKWMETQVTSTDDSDPWWAAFSGVFKDMKLALELEICPASTDARYIRAAGVPALGFSPMNHTPVLLHDHDERLHEAVFLRGVDIYTQLLSALASVPALPSES
What is the function of this protein?
Catalyzes the hydrolysis of N-acetylated amino acids to acetate and free amino acids.
What are the official names of this protein?
Aminoacylase-1, ACY-1, N-acyl-L-amino-acid amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STRZP
Sequence: MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MOAA_ECOLU
Sequence: MASQLTDAFARKYYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CCNB1_XENLA
Sequence: MSLRVTRNMLANAENNVKTTLAGKRVVATKPGLRPRTALGDIGNKAEVKVPTKKELKPAVKAAKKAKPVDKLLEPLKVIEENVCPKPAQVEPSSPSPMETSGCLPDELCQAFSDVLIHVKDVDADDDGNPMLCSEYVKDIYAYLRSLEDAQAVRQNYLHGQEVTGNMRAILIDWLVQVQMKFRLLQETMFMTVGIIDRFLQEHPVPKNQLQLVGVTAMFLAAKYEEMYPPEIGDFTFVTDHTYTKAQIRDMEMKILRVLKFAIGRPLPLHFLRRASKIGEVTAEQHSLAKYLMELVMVDYDMVHFTPSQIAAASSCLSLKILNAGDWTPTLHHYMAYSEEDLVPVMQHMAKNIIKVNKGLTKHLTVKNKYASSKQMKISTIPQLRSDVVVEMARPLM
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Nucleus.
Protein: NANO1_HUMAN
Sequence: MEAFPWAPRSPRRGRAPPPMALVPSARYVSAPGPAHPQPFSSWNDYLGLATLITKAVDGEPRFGCARGGNGGGGSPPSSSSSSCCSPHTGAGPGALGPALGPPDYDEDDDDDSDEPGSRGRYLGSALELRALELCAGPAEAGLLEERFAELSPFAGRAAAVLLGCAPAAAAAATTTSEATPREERAPAWAAEPRLHAASGAAAARLLKPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKVPPPPARPPPRSARDGPPGKKLR
What is the function of this protein?
May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets.  Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin.  Up-regulates the production of MMP14 to promote tumor cell invasion.
What are the official names of this protein?
Nanos homolog 1, NOS-1, EC_Rep1a.
What is the protein family that this protein belongs to?
Belongs to the nanos family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm. Note=Colocalizes with SNAPIN and PUM2 in the perinuclear region of germ cells.
Protein: Y1973_STAAC
Sequence: MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASVSFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSAEYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFIIAYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK
What are the official names of this protein?
UPF0316 protein SACOL1973.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T6501_BRUO2
Sequence: MTTKLHAVVDAIGLPLRIKPTPGHYGDCPQASSLLSGLKGVGHVIADAAYDADHLRAFIASNLKATAQIKVNPTRSSVPTIDWRLYKERHQIECFFNKLKRYRRIALRCEKTLTAFMGFVHLACAMIWLR
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Putative transposase for insertion sequence element IS6501.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: RS11_CLOD6
Sequence: MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNAISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRALQATGLEVTMIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LPXK_RICMO
Sequence: MIKLLYPEFWQKRNIIAYLLLPISLIYQFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKARNVSFVIVTKAYGSNLKSATTIHQGHTALEAGDEGVILAKYGAVIATKSIKEIVPLINELKPDTIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPNKVLDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPANNIDKTKNYFAFSGIGNPERFFATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVCLDVELSINNPDLLNEKIFKKAQIFN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.