PharMolix/UniProtQA huggingface dataset:
Protein: PME28_ARATH
Sequence: MSYGYDDEDAKRKKRYVIISISSVLLISMVVAVTIGVSVNKSDNAGDEEITTSVKAIKDVCAPTDYKETCEDTLRKDAKDTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRAKMALDQCKELMDYAIGELSKSFEELGKFEFHKVDEALVKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVTEMSNYLGQMQIPEMNSRRLLSQEFPSWMDARARRLLNAPMSEVKPDIVVAQDGSGQYKTINEALNFVPKKKNTTFVVHIKEGIYKEYVQVNRSMTHLVFIGDGPDKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIAFENTAGAIKHQAVAIRVLADESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKEQSKTYLGRPWKEYSRTIIMNTFIPDFVPPEGWQPWLGEFGLNTLFYSEVQNTGPGAAITKRVTWPGIKKLSDEEILKFTPAQYIQGDAWIPGKGVPYILGLFSGNGSTNSTVTGSSLSSNTTESSDSPSTVVTPSTSPPAGHLGSPSDTPSSVVSPSTSLPAGQLGAPPATPSMVVSPSTSPPAGHLGSPSDTPSSLVSPSTSPPAGHLGSPSDTPSSVVTPSASPSTSPSASPSVSPSAFPSASPSASPSASPSVSPSASPSASPQSSIG
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Putative pectinesterase/pectinesterase inhibitor 28.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RUVA_SYNS9
Sequence: MIGWLQGRHMECWTQGNRSGVLLVCAGVGYEVQLTSRHQKQLQPDSELTLWIHQVQREDGSSLFGFPSRQERDLFRLLIGVNGVGPQAGLALLHECKPQELVAAISGGDLKRLCQAQGIGKRTAERLAVDLRTPIAAFGGLEPQPSLVEGLASEQIPEAGEDVEATLISLGYDELEIRRAIRAIADGASGVPPSGTDQDGWLRSCLQWLSRESA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RLMN_CALS4
Sequence: MYNLKDMTLEEMEEFFVNLGESKFRAKQLYKWIYDKRVTDFDLMTDISKNLRAKLKEIAYISELKIIERRVSQIDDTVKYLFLLEDKNIIEGVAIKYKFGNTACVSTQVGCNMKCKFCASAIGGKVRDLKASEMVDQVMAIDSDYGKISNIVLMGSGEPFDNYDEVMKFIKIVNNPYGLKIGKRHITISTVGIVPKIYQFADEELQVNLSISLHAPNNELRNELMPINRAYPLEELMKACRYYIEKTNRRITFEYALIDGVNDKKEHAYQLVDLLKGMLCHVNLIPINYVKEIGFRKSNNEKVMMFKKIIENAGITCTVRRELGSDIEAACGQLRRKYLKEG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT110_ORYSJ
Sequence: MAPIGVLTALDQARTQYYHFKAIVIAGMGLFTDSYDLFCIAPVMKIVGRVYYSDGGARPGVTPPAVVSATVGVALLGAVIGNVVFGALGDRVGRRRVYGACLLLMVCSSVGSGFSVCRTRRCALASLCFFRFLLGVGVGGDYPLSATIMSEFANRRTRGAFIAAVFSMQGFGILASSAVTMAVAAAFDHYTGYPAPLDTPECADLAWRIILMAGAVPAALTYYWRMSMPETARYTALVERDVVKATNDIGRVLADLDLGAVAEEEVAAALSRPPPPPRPSYGLLSRRFVRQHGRDLFACAAAWFLLDIPYYSSTLFQSQIYRPLFPAPGLINAFQEAFNVAKFQAVIAVASTIPGYFVAVLLIDRVGRRCLQMAGFLLMAVFLFALAGPYDGYWRDHGAHAGYIVLYSLTFFSANLGPNTTTFILPAELFPARFRSTCHGLSGAAGKLGALVGSIGFLWASQQKDGAAAGHLPGIGMMYALFVLGGICLLGLALTYVFTPETMMRSLEENESDRAQTQVGDGGSDTEAAKSPASMASSHLSMSPILPARVSV
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-10, OsPT10, OsPht1;10, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SAFA_ECOSM
Sequence: MHATTVKNKIMQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQQGISEMGRMARDLTHFIINSLQD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: Y3165_CLOBK
Sequence: MPRPTKFRRVEFFPENNYFVPWGKPKCEIHEVVLKVEELEAMRLKDIEELNQEQCAEKMEISRQTFQNIIDSARKKVAIALTEGNAIKISGGHYTTKLCKLKCIDCEEIYEINYEQDRHLCPNCGSEKVICNKKADFCRRWCKGQNRKEQYEESKNK
What are the official names of this protein?
UPF0251 protein CLD_3165.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: ASCC3_DANRE
Sequence: MVDVNDVIHANEKAQIDFAQMLLPEGIRRDNNKMYEEVEIPPNEPMPIGFEEKAVFVSELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPFIGLFYFDSRFRPVPLGQSFVGIKTTNKVQQLHDMEEVCYEKVLKQIKAGHQVMVFVHARNSTVRTAMSLIEMAKNRGELSFFQVDQGADYGQCEKQIQRSRNKQMREMFPDGFGIHHAGMLRQDRSLMESMFSRGYLKVLVCTATLAWGVNLPAHAVIIKGTNIYDAKRGTLVDLGILDVMQIFGRAGRPQFDKYGEGTIITTHDKLSHYLTLLTQQNPIESQFQQSLADNLNAEIALGTVTNVDEAVRWLSYTYLYVRMRANPLAYGINHKAYQMDPQLELYRKELVVESGRKLDKARMIRFDERTGYFASTDLGRTASHFYIKYNTIESFNELFNAQNTEADVLSIVSKAEEFEQIKVRVQEEDADGKSSVQILCGSHHTNAARIMRALFEMALRKRWPAMTYRLLNLCKVMDKRLWGWAHPLRQFNTLPASALARMEDKNLTIDKLRDMGKDEIGHMLHHVNIGLKVKQCVHQIPAILLESSIQPITRTVLRVRLSITPDFRWNDQVHGSVGEPWWLWVEDPINDHIYHSEYFLLQKKQVVSGEPQQVVFTIPIFEPMPSQYYIRAVSDRWLGSEAVCIINFQHLILPERHPPHTELLDLQPLPITALGNREYESLYKFTHYNPIQTQIFHTLYHTDTNVLLGAPTGSGKTIAAEMAIFRVFNMYPTSKVVYIAPLKALVRERIEDWKIRIEEKLGRKVVELTGDNTPDMRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLGEDRGPVLEVIVSRTNFISSHTSKTVRVVGLSTALANARDLADWLGIGQVGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMATMNKPVFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLATEDDPKQWLHQDEREMTDIIATIRESNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEYYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLSVLSDHLNAEIAAGTVTSKQDAMDYITWTYFFRRLVMNPSYYNLDDISHETINKYLSNLVERSLRDLECSYCMEIQQDEQTIEPLTYGRISSYYYLKHQTIRMFKERLKPELPVHELLAILSLPCSDYGTDTKTVLDNAIRICQAMLDVVANEGWLVSALSLCNLVQMIIQARWLHDSSLLTLPHIQKQELYVFRRWSSRGVRAGCGHQGPIEGLPELIAACDGKEDIFTSMVKEVLQPNQISQ
What is the function of this protein?
3'-5' DNA helicase involved in repair of alkylated DNA.  Promotes DNA unwinding to generate single-stranded substrate needed for alkbh3, enabling alkbh3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions.  Also involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation.  Drives the splitting of stalled ribosomes.
What are the official names of this protein?
Activating signal cointegrator 1 complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm, cytosol. Note=Colocalizes with alkbh3 and ascc2 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage.
Protein: VGLG_TRTV
Sequence: MGSKLYMVQGTSAYQTAVGFWLDIGRRYILAIVLSAFGLTCTVTIALTVSVIVEQSVLEECRNYNGGDRDWWSTTQEQPTTAPSATPAGNYGGLQTARTRKSESCLHVQISYGDMYSRSDTVLGGFDCMGLLVLCKSGPICQRDNQVDPTALCHCRVDLSSVDCCKVNKISTNSSTTSEPQKTNPAWPSQDNTDSDPNPQGITTSTATLLSTSLGLMLTSKTGTHKSGPPQALPGSNTNGKTTTDREPGPTNQPNSTTNGQHNKHTQRMTPPPSHDNTRTILQHTTPWEKTFSTYKPTHSPTNESDQSLPTTQNSINCEHFDPQGKEKICYRVGSYNSNITKQCRIDVPLCSTYSTVCMKTYYTEPFNCWRRIWRCLCDDGVGLVEWCCTS
What is the function of this protein?
It is likely to be the virus attachment protein.
What are the official names of this protein?
Major surface glycoprotein G, Attachment glycoprotein G.
What are the subcellular locations of this protein?
Host cell surface. Virion membrane. Note=Expressed on the surface of the infected cells and incorporated in the membrane of the virions.
Protein: PGPI_RAT
Sequence: MEQPRKAVVVTGFGPFGEHAVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQLVVHVGVSGMATTVTLEKCGHNKGYKGLDNCRFCPGSQCCVEDGPESIDSIIDMDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYRGRGRSAFVHVPPLGKPYNADQLGRALRAIIEEMLGVLEQAEGDISCCHQL
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyroglutamyl-peptidase 1, 5-oxoprolyl-peptidase, Pyroglutamyl aminopeptidase I, PAP-I, Pyroglutamyl-peptidase I, PGP-I, Pyrrolidone-carboxylate peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NINF_BPP22
Sequence: MLSPSQSLQYQKESVERALTCANCGQKLHVLEVHVCEACCAELMSDPNSSMYEEEDDG
What are the official names of this protein?
Protein ninF.
What is the protein family that this protein belongs to?
Belongs to the ninF family.
Protein: CYSI_SALTY
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVKPQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGSRIPRMYKENIAEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: NCAP_PI3H4
Sequence: MLSLFDTFNARRQENITKSAGGAIIPGQKNTVSIFALGPTITDDNEKMTLALLFLSHSLDNEKQHAQRAGFLVSLLSMAYANPELYLTTNGSNADVKYVIYMIEKDLKRQKYGGFVVKTREMIYEKTTEWIFGSDLDYDQETMLQNGRNNSTIEDLVHTFGYPSCLGALIIQIWIVLVKAITSISGLRKGFFTRLEAFRQDGTVQAGLVLSGDTVDQIGSIMRSQQSLVTLMVETLITMNTSRNDLTTIEKNIQIVGNYIRDAGLASFFNTIRYGIETRMAALTLSTLRPDINRLKALMELYLSKGPRAPFICILRDPIHGEFAPGNYPAIWSYAMGVAVVQNRAMQQYVTGRSYLDIDMFQLGQAVARDAEAQMSSTLEDELGVTHEAKESLKRHIRNINSSETSFHKPTGGSAIEMAIDEEPEQFEHRADQEQDGEPQSSIIQYAWAEGNRSDDRTEQATESDNIKTEQQNIRDRLNKRLNDKKKQGSQPSTNPTNRTNQDEIDDLFNAFGSN
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL13_DICTD
Sequence: MKTFMAKKEEIKREWYVVDAKGKVLGRLASEIAKILRGKHKPIYTPHVDTGDFVIVVNAKDVVLTGKKEDQKIYFFHSGYPGGHRLITARDMRAKSPEKMIYLAVKGMLPKGPLGRKMLKKLKIYAGPEHPHQAQKPKELNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS10_METBU
Sequence: MAQKARIRLSGTSPVNLDGVCDQVKAIANRTGVSISGPVPLPTKKLVVPVRKSPSGDGTATWDHWEMRVHKRLIDIAADERALRQLMRIQVPKDISIEIVLQN
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SYS_LIMF3
Sequence: MLDIKQIRQQPDWFKEKLATRGVQPEEIDTVLELDAKRRELLQQTETLKAKRNEASKKIGEAKRAKQSADEAIAEMRQVGEDIKALDEQVEANDKDLFDKLAHLPNVPHEGVPVSLTEDGAEELRKVGQARQFDFEPKHHWEIGENLGILDFERAGKVSGSRFVYYVGLGAQLERALYNFMLDEHMKEGYTEVLPPYIVNAHAMYGTGQFPKFKQDVYQVNGEDMTLIPTAEVPLTNYFAGEVIPAEKLPVYVTALTPSFRSEAGSAGRDTRGLIRMHQFNKVEMVKYTKQDQSWEELDKMTANAENILQKLGLPYHVITLTTSDMSFTASETHDLELWMPAQNKYREVSSCSNCLDFQARRLHMQYRDENGKLQYVHTLNGSGLAVGRTLAAILENYQNEDGSVTIPEVLVPYFHGITKITKENAVPFNNK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER2_RICRI
Sequence: MSGKIKVTFIINDGEEKTVEAPIGLSILEIAHSNDLDLEGACEGSLACATCHVILEEEFYNKLKKPTEAEEDMLDLAFGLTDTSRLGCQIILTEELDGIKVHLPAATRNIKL
What is the function of this protein?
Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
2Fe-2S ferredoxin, Adrenodoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: VAPB1_HAEI8
Sequence: MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system (PubMed:25391136, PubMed:27672196).  Neutralizes the effect of cognate toxin VapC1 (PubMed:25391136, PubMed:27672196) but not non-cognate toxin VapC2 (PubMed:27672196).
What are the official names of this protein?
Antitoxin VapB1, NTHi VapB1.
What is the protein family that this protein belongs to?
Belongs to the VapB family.
Protein: DUT_SHEWM
Sequence: MKTPIEVKILDSRIGSEYPLPAYATPGSAGMDLRAMIETSLSVAPGETRLIPTGISIHVADPSLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRGDKPYTIEIGDRLAQLVFVPVVQAEFKLVDEFDNSLRGEGGFGHSGTS
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: LEUC_SYNS9
Sequence: MSSGTLYDKVWDLHRVADLPGGSTQLFVGLHLIHEVTSPQAFSGLRDKGLKVACPERTVATVDHIVPTTSQARPFADPLAEEMLSTLERNCAESGIVLNGIGSGRQGIVHVIAPELGLSQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMNKLKVRRILVNGQLSAGVSAKDLVLHVIRTLGVKGGVGYAYEFAGSAIEALSMEERMTLCNMAIEGGARCGYVNPDQTTFDYLKGRPHAPSGAAWDAAVDWWLSLATDAAAEVDDEVVFDATVIAPTVTWGITPGQGLGIDECVPSLSMLDPGERPIAKEAYRYMDLDPGTPIAGVPIDVCFIGSCTNGRLSDLRAAAAVARGRQVAKGVKAFVVPGSEQVARAAEAEGLDQVFSEAGFEWREPGCSMCLAMNPDRLEGRQISASSSNRNFKGRQGSASGRTLLMSPAMVVAAAVHGRVTDVRTLALHSAS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYW_STRMU
Sequence: MSKPIILTGDRPTGKLHLGHYVGSLKNRVLLQNENKYEMFVFLADQQALTDHAKESEIIKDSIANVALDYLSVGLDPEKVTIFIQSQIPELAELTMYYMNLVSLARLERNPTVKTEIAQKGFGESIPTGFLVYPISQAADITAFKANYVPVGNDQKPMIEQTREIVRSFNHTYKTNCLVEPEGIYPKNEAAGRLPGLDGNAKMSKSLGNGIFLSDDADTVRKKVMSMYTDPNHIRVEDPGQIEGNMVFHYLDIFGRKEDQTDIAAMKEHYQSGGLGDVKTKHYLLDILERELTPIRRRRLEYEKNMDQVLDILKKGSETARETASETLSGVKRAMGINYF
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIS_METLZ
Sequence: MKPATLEFLRQRFFAYYNGAIPGAGAGYSPESLTEREWGFLFFTENQRSGMRRHISFTSQDELTSYLKSMVPAHVYYSTAYYTHPGAAQMADKEWRGADVIFDLDADHIVRGPYDIMLARVKEELFKLIDMLTGELGFAKRDLRINFSGGRGYHVHLPLLSVRGWDTAERRELVNYVSGTGLSFDSMMAPSQKSGWKLRYHDALNDELARIAGLPCEDALSYLSGLSGISETFAAGFLKNISQTQNLLKSNPEKLLANKVVRAIANAENEPFQAGILSRAAQADEPVTTDVKRLIRHPGSLHGGSGMRVVPISVDQLDAFDPLIDAVVFGERNVSVDCAFNLSMPILGNNYTLTAGRNVVPEALGVFLCCRGIAELSGGI
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: FX1_CONVC
Sequence: MQRGAVLLGVVAFLALWPQAGAEPYNLNDPDVRAMINDGRKLMDTCAKANHYIADRWSTYRIEYLEDKGLYHRMLRELVPCLNNFLRTRQEAP
What are the official names of this protein?
Conotoxin F_Vc1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin F superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_CLOD6
Sequence: MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNLKTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAIKFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVVQVPLFINTGDKVKIDTRTGEYLSRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KISSR_HUMAN
Sequence: MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPHAELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL
What is the function of this protein?
Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1.  KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity.  The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells.  The receptor is essential for normal gonadotropin-released hormone physiology and for puberty.  The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.  The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself.  Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
What are the official names of this protein?
KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, hOT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GFRA4_CHICK
Sequence: MRGILYFCTLILLEGMAEAVSSSRDCLQAGESCTNDPICSSKFRTLRQCIAGNGANKLGPDAKNQCRSTVTALLSSQLYGCKCKRGMKKEKHCLSVYWSIHHTLMEGMNVLESSPYEPFIRGFDYVRLASITAGSENEVTQVNRCLDAAKACNVDEMCQRLRTEYVSFCIRRLARADTCNRSKCHKALRKFFDRVPPEYTHELLFCPCEDTACAERRRQTIVPACSYESKEKPNCLAPLDSCRENYVCRSRYAEFQFNCQPSLQTASGCRRDSYAACLLAYTGIIGSPITPNYIDNSTSSIAPWCTCNASGNRQEECESFLHLFTDNVCLQNAIQAFGNGTYLNAATAPSISPTTQMYKQERNANRAAATLSENIFEHLQPTKVAGEERLLRGSTRLSSETSSPAAPCHQAASLLQLWLPPTLAVLSHFMM
What is the function of this protein?
Receptor for persephin.  Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).
What are the official names of this protein?
GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: YD102_YEAST
Sequence: MTLLLQKCIRVELRKDPIFNASSSLEIFLSVLESVIYPFKGNLILLDFHLVDVQTTCYQRNSSMRNQLMSVFCQSLREFTLTALSCNSYCIIIVATRWQKIDNALKMTGR
What are the official names of this protein?
Uncharacterized protein YDR102C.
Protein: Y1011_RHIME
Sequence: MGETPFWKTKGLEEMTGAEWESLCDGCGLCCLNKLEDWDSSEIAWTSIRCTLLDGESCRCKDYDNRQATVPDCIQLTPKAVREISWLPPTCGYRLVAEGRDLYWWHPLVSGDPETVHAAGISVRGRTVAEDGIDIEDYEDYLVTWPLEVGREPAD
What are the official names of this protein?
UPF0260 protein R01011.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: TFE_METM7
Sequence: MLENPLIQQVLFEIMDEDVVGFDVLSVLINTNEVTDDEISRQLDVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKVPALVAKKMKNVLKDLKEQLELEETNMFFFCSDCEIKFTFEDAMDSGFRCPQCGGMMYEYDNKKDISILKEQINYLEDEFNKNPLFSAY
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.