PharMolix/UniProtQA huggingface dataset:
Protein: SYV_XYLFT
Sequence: MSQFTSSYDPTSFEARLYAEWEAAGHFKPSGVGQPYTILLPPPNVTGTLHMGHAFQQTLMDALVRYHRMCGDDTLWQVGTDHAGIATEMVVSRNMALEGRGETRDSLGREGFINKVWEWKQQSGDTIERQMRRLGVSADWSRSTFTMDAQPSAAVTEAFVRWYEEGLIYRGQRLVNWDPVLKTAISDLEVENVQEEGMLWSIRYPLSDGVTYEHIEHDAAGNETLRETRDSLIVATTRPETLLGDTAVMVHPEDRRYTALIGKTVTLPLTGRQIEVISDTYVEPTFGTGVVKVTPAHDFNDYQVGLRHRLPMIQVLDDAACIVSKTSIQSGIASGATSDTTDTPSDSDASNASNQHDTLIMPAHLAGLDRYEARKQILADLDAQGLLVAATPHTLQVPRGDRTGQVIEPYLTAQWFVRMETLAARGLELVERGAVRFVPPNWINTYRHWMENIQDWCISRQLWWGHRIPAWFDTQGCVYVGRSEAEVRAKHALGPEVTLTQDNDVLETWFSSQLWPFSTLGWPDPMAMAERGFERYLPSSVLVTGFDIIFFWVARMIMATDHFTGNVPFHDVYITGLIRDAQGQKMSKSKGNVLDPLDIIDGITLDDLVAKRTTGLMQPKLAEKIAKATRKEFPDGIAPHGADALRFTIAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFVLMNTAGDTAHSPAQHQAGQDGQDVPRTPQPRTDAEQWILSRLAAVTAEAHAQFAAYRFDLLAQALYEFAWNEFCDWFVELAKPALNGDDTQAAASTRHTLLYVLETLLRLLHPLIPFITEELWCQVAPRLGIQATTLMLRPYPQPQQLETTAFANAAADVEWLKIMVSALRRIRSTLNVPPSRRISLLLQGGQEVDRRRITHFAIALHFLLKLEHIDWLSATTAAPPSATAIVGSLKLLVPLEGLIDVDAERARLDKEIKRVESEIDKSNGKLSNAVFVQNAPTAVVEQERSRLREWTTQLNGLRERRTTL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDSA_STAAN
Sequence: MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNMNMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLKSLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLWPVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVESGFKRHFGVKDSGRILPGHGGILDRFDSFMFVLPLLNILLIQS
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F16PA_YERPS
Sequence: MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGEDQMKLDLFANEKLKAALKARGEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVAAGYVVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSRYIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRILDIVPEKLHQRAPFFVGTKSMVEDAEGFIAKFPDEEAK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_RHIME
Sequence: MDIEKYSERVRGFLQSAQTYALAEGHQQFTPEHVLKVLLDDDQGMAASLIERAGGNAREAKVGTAAALAKLPKVTGGNGSVYLSQPLAKVFTAAEDAAKKAGDSFVTVERLLLALAIESSAATASILSKAGVTPTKLNQVINEIRKGRTADSANAEQGFDSLKKYARDLTAEAREGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKRLMALDMGALIAGAKFRGEFEERLKAVLNEVRSEGGEIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVMVEEPTVEDTISILRGLKEKYEQHHKVRISDSALVAAAALSNRYITDRFLPDKAIDLMDEAASRLRMQVDSKPEELDELDRRVIQLKIEREALKKETDVSSKDRLAKLELDLSSLEEEAAALTARWQAEKQKLGQAADLKKQLDEARNELQIAQRKGEFQRAGELAYGVIPNLEKELAEAESQDGASANPMVQEVVTPDNIAHIVSRWTGIPVDKMLEGERDKLLRMEDELAKWVVGQGDAVQAVSRAVRRSRAGLQDPNRPIGSFIFLGPTGVGKTELTKALARFLFDDETALMRIDMSEYMEKHSVARLIGAPPGYVGYEEGGALTESVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTMIIMTSNLGAEYLTALGENEDSDAVRDQVMEVVRAAFRPEFLNRVDEIILFHRLRRSEMGAIVDIQLERLRKLLSDRKITLELEDDARVFLADRGYDPAYGARPLKRAIQKYVQDPLAEKVLQGEFPDGSVIKVVAGSDRLNFKRGAGANKEAA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_NOSP7
Sequence: MVNILHIDSSPRAERSHSRELSKEFVSAWRAAHPEDAIAYRDLGHHPVPHVNEAWIAAAFSPPETHTPELAEAIRVSDELVDEFLAADRYVFGVPMYNFNIPSTFKAYIDQIVRINRTVSLDAQGFRGLVEGKKAVIITARGGDFSATSPAVAYDFQEPYLRTIFGFIGITDIQFINANSLNEGDARTQSLAEARAAIQDAIAQW
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NU6C_SYNY3
Sequence: MNLAEGVQYISFLILAFLVIGAALGVVLLSNIVYSAFLLGGVFLSISGIYILLNADFVAAAQVLVYVGAVSVLILFAIMLVNKREDFSKIPGRWLRNVSTALVCTGIFALLSTMVLITPWQINETGPFVENTLVTIGKHFFSDYLLPFELASVLLLMAMVGAIILARRDLIPELSEENKTATALTLPERPRELTSASK
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 6, NAD(P)H dehydrogenase I, chain 6, NDH-1, chain 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL36_CLOD6
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: UEV1A_ARATH
Sequence: MSSEEAKVVVPRNFRLLEELERGEKGIGDGTVSYGMDDADDIYMQSWTGTILGPPNTAYEGKIFQLKLFCGKEYPESPPTVRFQTRINMACVNPETGVVEPSLFPMLTNWRREYTMEDILVKLKKEMMTSHNRKLAQPPEGNEEARADPKGPAKCCVM
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  May play a role in the control of progress through the cell cycle and differentiation.  Probably not involved in the error-free DNA repair.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 1A, Ubc enzyme variant 1A, Protein MMS ZWEI HOMOLOG 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: Y1590_CALMQ
Sequence: MVTRKPAVAGMFYEASKDGLINQIKWSIEHELGPKSTMNVKENRQYVLSVIVPHAGYVYSGPVAAHAYVEVGKYIKPKVFVIIGPNHYGVGSPAAIMTSGTWETPLGQVEIDEEVAKQIKAKVKDLAEDPIAFEREHSIEVQVPFIQYLFPGSRIVPIVLWNQTIDLSRRLGSAISEVIDGRAGEVVVVASSDLNHYEPHEVTTDKDMKVIERILNMDEEGFYTVMDKYDVSVCGFGAIMTAIVYSRKQGSTGVKLLKHATSGDTSGYLLETVGYASIAFYK
What are the official names of this protein?
MEMO1 family protein Cmaq_1590.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: RUTA_ECOK1
Sequence: MQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIENFGERIQPLMQCRAHLPALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: ACTN4_PONAB
Sequence: MVDYHAASQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICRVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein.  Probably involved in vesicular trafficking via its association with the CART complex.  The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.  Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2.  Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.  May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.
What are the official names of this protein?
Alpha-actinin-4, Non-muscle alpha-actinin 4.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, perinuclear region. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity).
Protein: EX53_HALH5
Sequence: MHSPVLLLIDGFNLLSRGYFATSYGKDEAQLPRNEAGYYINALRVFFPKLFQLIREHNVTHVAVAWDVKREDSHRRQAFAFYKASRGELPEALIEQYETATSLLEEIGVAQVTIPPYEADDTIGAFACRWAKEEKGHCFIYSNDRDLLQLLSKSTSQIISSKGKDLIYTEENFRNDYNISPAQWVDVKALLGDKSDNIPGCPGVGEKSALPLIQQYGTIETLYEQIEDLDPKYKRYHKKLVAGEESVIISKELATITTEIEAISSFSLNSLVLTTPADLIIDTLARCGIRVKLAPVQTELKLG
What is the function of this protein?
5'-3' exonuclease acting preferentially on double-stranded DNA.
What are the official names of this protein?
5'-3' exonuclease.
Protein: LEUD_BURM1
Sequence: MEKFTVHTGVVAPLDRENVDTDAIIPKQFLKSIKRTGFGPNAFDEWRYLDHGEPGQDNSKRPLNPDFVLNQPRYQGASILVTRKNFGCGSSREHAPWALQQYGFRAIIAPSFADIFFNNCFKNGLLPIVLTEQQVDHLINETVAFNGYQLTIDLEAQVVRTPDGRDYPFEITAFRKYCLLNGFDDIGLTLRHADKIRQFEAERLAKQPWLNNKLVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: ATPB_ADIRA
Sequence: SVPVGETTLGRIFNVLGEPVDNLGPVQNSTTFPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVSGGVGERTREGNDLYMETKESKVINEQNIAESKVALVYGQMNEPPGARMRVGLTASTMAEYFRDINKRDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPWIVGEEHYETAQGVKQTLQRYKELQDIIAIPGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVSLPETIKGFQMILPGELDNLPEQASYLVGNIDEAAAKAAALQAGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GNL3_XENLA
Sequence: MKRPKLRKSSKRLSCHKRYKIQKKVREHKRKVKKEAKKSGPRKHKKDITVPNAAPFKAQILQEAQLRRQQQEELKQKQKLDRQKEVAKKRKLEEKKNNNSEKKEKRDKKRKETKTPDDPDVVLCRQVNKVLEQSDVIVEVLDARDPLGSRCSQAEEVVLKSPNKRLLLLLNKSDLVPREMVEKWLQVLSAELPTVPFRCVAQIQDKSEKKKKKKVPVSADLVTDPKCPGGQVLLKILHSLCPSHNEAIKVGVIGFANVGKSSVINSLKQSHVCNVGPSKGTTKFLQEVRLDPQIRLLDSPALLVSPHNPPVALMLRSASESKVDVLAAVEAILKHCSKQELMLHYTIADYRNSLECLTLLAHRRGMLKKGGVPDTEGAGRLLFNDWMGARMKYYCRPPDSPVCQPHISREVVAAMSSGICSEELAMDNASTLKALKCPNSANIVVFASVGPTSAIMDETQLVDPEPELIEEELEENDGEEEEDMEEEEDDDEGSEEEEDLEAKSLTQEVTSAKEKDSKSAGPAVSFDQAADDDTYDFNTDFV
What is the function of this protein?
May play a role in regulating cellular proliferation.
What are the official names of this protein?
Guanine nucleotide-binding protein-like 3, Nucleostemin-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus.
Protein: DTD_STAAW
Sequence: MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_PROM4
Sequence: MVSIRPDEISSILKQQIANYDKSVSVSNVGTVLQIGDGIARIYGLEKVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEALGVQEGSTVKSTGKIASVPVGQAMLGRVVNPLGQPVDGNGDIATSDSRLIESLAPGIIKRKSVHEPMQTGITSIDAMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVVCVYVAVGQKSASVAQVVEVLREKGALEYTIVVNASASEAAALQYLAPYTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSESMGSGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLRELLKQAQFAPLNLAEQVAVVYAGVKGLIDEVPVEQVTQFAGELREYLKTSKPDYIKQVLTEKKLNEEIESVLKESINEVKSSMLAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: MDHC_XENLA
Sequence: MPEPVKVLVTGAAGQIAYSLLFGIAKGDVFGKDQPLILVLLDITPMMTVLEGVVMELQDCALPLLKEVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALNKYSKKSVKVIVVGNPANTNCLTALKSAPSIPKENFSCLTRLDHNRAKAQIALKLNVASDDVKNVIIWGNHSSTQYPDASHASVTLQGKDVGAFEAVKNDDWLKGGFITTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGQFVSMGVISDGNSYGVPEDLMYSFPLTIKNKTWKIVEGLCINDFSREKMDITAKELQDEKETAFEFLSSE
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I69A2
Sequence: MNPNQKIITIGSASLGLVFLNVILHVVSITVTVLVLSNNVTGPNCNGTIIREYNGTVRIERITQWYNTNIIEYIERPSNEYYMSNTEPLCEAQGFAPFSKDNGIRIGSKGHVFVIREPFVSCSPLECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVEVGQSPNVYQARFEAVAWSATACHDGKKWMTVGVTGPDAQAVAVVHYGGVPVDVINSWAGNILRTQESSCTCIKGDCYWVMTDGPANRQAQYKIFKAKDGRIIGQTDVNFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPVLVISPDLSYTVGYLCAGIPTDTPRGEDSQFTGSCTKPLGNQGYGIKGFGFRQGNDVWAGRTISRTSRSGFEIIKIRNGWTQNSKDQIRKQVIVDNLNWSGYSGSFTLPVELTKKGCLVPCFWVEMIRGKPEEITIWTSSSSIVMCGVDHKVASWSWHDGAILPFDIDKM
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: RSSA_CANAL
Sequence: MSLPASFDLTPEDAKLLLAANVHLGAKNVQVHNKPYVYKTRPDGMNIINIGKTWEKIVLAARIIAAVPNASDVAVCSSRTFGQRAVLKFAAHTGATAIAGRFTPGNFTNYITRSFKEPRLVVVTDPRTDAQAIKESSYVNIPVIALTDMDSPSEYVDVAIPCNNKGKHSIGLIWWLLAREVLRLRGIIPDRTTEWSVMPDLYFYRDPEEIEQNAVEEAKTEEVEEAPVAEAETEWTGETEDVDWADSGATPAAEDAAASNW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBSAG_HBVB5
Sequence: MGGWSSKPRKGMGTNLSVPNPLGFFPDHQLDPAFKANSENPDWDLNPHKDNWPDANKVGVGAFGPGFTPPHGGLLGWSPQAQGLLTTVPAAPPPASTNRQSGRQPTPLSPPLRDTHPQAMQWNSTTFHQTLQDPRVRALYFPAGGSSSGTVSPAQNTVSTISSILSKTGDPVPNMENIASGLLGPLLVLQAGFFLLTKILTIPQSLDSWWTSLNFLGGTPVCLGQNSQSQISSHSPTCCPPICPGYRWMCLRRFIIFLCILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWFWGPSLYNILSPFMPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: THIC_ANASK
Sequence: MRADWIAKRRGQANVSQMHYARSGVVTEEMAFVAARERLEPELVRAEVARGRMVIPANVRHPELEPLAIGITACCKINANIGNSAVTSNIDEELAKLRVCLKYGADTVMDLSTGGDIPQIREAILRASPIPVGTVPIYECLAHVKDVADLTPELMLEIIEAQAAQGVDYMTIHAGVLRDFIPLAAHRITGIVSRGGALMAQWMLANKAENPFFTHFEQICEIFKRYDVTFSLGDGLRPGCLADASDAAQFAELKALGDLTRKAWEHGVQVMVEGPGHVPLDQIPMNMEKERELCSEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGAAMLCYVTPAEHLGLPDIDDVREGIVAYKIAAHAADVARHRPGARDRDDALSRARYAFDWNKQFELSLDPDTARAKHDETLPHEAFKSAEFCSMCGPKFCSMKIHGHLAEAAAAQDAAANGAAGKPAGGLQVLP
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y040_MYCPN
Sequence: MSSVFSKPNLKRPSFDVKNLTKPSRLLSATLRSSCAFLSSASFFACSLCFFCCSSISFCSLASSSARLRYSSSHSFFCWVLFSRSGLAYSSSNLSSKSSRLRS
What are the official names of this protein?
Uncharacterized protein MPN_040.
Protein: RBL_NICAC
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQTETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFVEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRLALEACVQARNEGRDLAQEGNEIIREACKWSPELAAACQVWKEIVFNFAAVDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.