PharMolix/UniProtQA huggingface dataset:
Protein: RL2_METTH
Sequence: MGKRLISQRRGRGTPTYRSASHRFKGKIKYRAYDSIESEGSLKGKVVDIMHDPGRTAPVARVKFENGEERLILAPEALMLNEEVECGVKARVKPGNSLPLSEIPEGTPIYNIENRPGDGGKLVRSSGTYASLITHDADKAVIELPSGELKALNPQCRATVGVVAGGGRREKPFLKAGKKYHALRAKGKKSVTVRGVAMNAVDHPHGGGNRQHPGRPTTVSRHAPPGRKVGSIAARRTGKRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FABZ_ECOLI
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, 17 kDa actomyosin component, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCEA_KLEPN
Sequence: MREISQKDLNLAFGAGETDPNTQLLNDLGNNMAWGAALGAPGGLGSAALGAAGGALQTVGQGLIDHGPVNVPIPVLIGPSWNGSGSGYNSATSSSGSGS
What is the function of this protein?
Channel-forming bacteriocin.  Forms cation-selective channels.  Active on enterobacteria, with highest activity against E. coli.  Not active on other Gram-negative bacteria, Gram-positive bacteria or fungi.  The unmodified protein is active against E. coli and S. enteritidis.  When the siderophore ester is present at Ser-99, antibacterial activity against these species is increased and activity is also detected against E. cloacae and K. pneumoniae.  Neutralized by its immunity protein MceB (PubMed:9864332).
What are the official names of this protein?
Microcin E492, MccE492.
What is the protein family that this protein belongs to?
Belongs to the class IIa microcin family.
Protein: NUOI_RICPR
Sequence: MINYLKSFFLYEIIRGMTLTLKYFFKPKVTINYPYEKSPVSPRFKGEHALRRYENGEERCIACKLCEAICPAQAIVIESDERDDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFASLTHTALIYDKERLLNNGDKWEQALANKLHKDYQYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: T4S20_BOVIN
Sequence: MTCCEGWTSCNGFSLLVLLLLGVTLNAIPLILNFVDEDQFFENPISCFEWWFPGIIGAGVMAIPATTMSLAARKRACCNNKTGMFLSSLLNAITVIGAAYCLLVSIQALAEGPLICNSQSNTTSSCEFSLKNLTANYKESFDLQWFFEDSCVPHTDSNNPSITNTTANNWRVYNLHFNSIENQHRIIHFSVFLGLLLVGILEILFGLSQIIIGFFGCLCGGVSNGRSQIV
What is the function of this protein?
Polytopic transmembrane protein.  Inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis.  In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1.  Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.
What are the official names of this protein?
Transmembrane 4 L6 family member 20.
What is the protein family that this protein belongs to?
Belongs to the L6 tetraspanin family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Ceramide alters the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20.
Protein: RL3_STAA2
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PNP_ACIF5
Sequence: MTMIRKEVDFGGRRLQLETGRMARQADGAVLVSSGDTVVLVTAVGRREMKPGQDFFPLTVNYQEKAYAAGKIPGGFFKREGRPTEKETLTSRLIDRPIRPLFPKGFMNEVQVIATVVSVDRDNDPDILALVGASAALAVSGIPFNGPIGAARVAYIDGKYVLNPSYAQLTTSQLDLVVAGTRQAVLMVESEAQQLSEEIMLEAVMFGHAQFQPVIETIEALAREAGKPRWEWVAPVADEALGVQVREKATPLLQEAYALTEKQARSKRLEDVQQAMAVEFGSDDAGRGDMVRGLLKKIETGIVRGRILDGAPRIDGRDSKTVRPITIEAGVLPRTHGSALFTRGETQALVVATLGTKGDEQIIDALQGESRDRFMLHYNFPPFSTGETGMVGSPKRREIGHGRLAKRAIAAVLPTDSEFPYSLRVVSEVLESNGSSSMATVCGASLALMDAGVPLKAPVAGVAMGLIKEGARFAVLTDILGDEDHLGDMDFKVAGTEQGVTALQMDIKIDGITREIMAQALQQALAGRLHILGLMNGVLSRGRGELSDYAPRIITIQINPDRIRDVIGPGGKVIRALTEETGATIDIQDNGTVTIASVDGEAGAAAKRRIELLTADVQVDTIYDGKVAKIMDFGAFVTILPGRDGLLHISQISNERVSDVHDHLKEGQAVRVKVLEVDRQGKIKLSMKDIPQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRE5_CONVL
Sequence: MGFRVLVLVVMATTSALPFTFSEEPGRSPFRPALRSEEAQALRHGLTLLLARRADGQPPDMRQPEMRRPEVRQPEFAELSVGQRRWDVDQCMYYCLTGVVGYSYTECQTMCT
What are the official names of this protein?
Conotoxin vil14.5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin R superfamily.
Protein: RECA_STRS7
Sequence: MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFDEIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_DROYA
Sequence: MFSIIIIASVILLITTVVMFLASILSKKALIDREKSSPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPMIIILKYSNIMIWTITSIIFILILLIGLYHEWNQGMLNWSN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RS4_NATTJ
Sequence: MARYQGPVCRLCRREGTKLFLKGERCYTDKCAIDKKAYAPGQHGPTRRSKQSEYGMQLREKQKARRIYGVLENQFRRYFREADRKKGITGQTLLRLLETRLDNVVYRMGFAASRAEARQFVNHGHIMVNGKRVNVASYEVKPGDEVVVREKSRDIPRVQELKELAEGYRVPEWLEADHENFTGRVVRYPEREEIDVPVEEHLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: FIXB_SINFN
Sequence: MGTRKSKASPPAQARASMKKDLPEQFRDYRHVWVFMELERGHVHPVSFELLGEGRRLADQLGVQLAGIILGPPGDSTLHAAAEAFAYGADLVYLVEEPLLTDYRNEPFTKALTDLVITHKPEILLLGATTLGRDLAGSVATTLLTGLTADCTGLDVDEDGSLAATRPTFGGSLLCTIYTLNCRPQMATVRPRVMRMPQRSNKPIGRVIRHDWRMLEEDIVTKVVGFLSDDRSGNANLAYADVVVAGGLGLSNAENLLLIKDLALTIGGDYGCSRPLVQKGWMPADRQIGQTGKTIRPKLYIAAGISGAVQHRVGVEGADLIVAINTDPHAPIFDFAHVGVVTDAVSFLPALTEAFTKRLAPANRLRVVN
What is the function of this protein?
May play a role in a redox process involved in nitrogen fixation.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: FLGI_SALCH
Sequence: MYVFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGVGASAGGSSVQVNQLNGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDARTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: RS16_ELUMP
Sequence: MAVVLRLQRVGKKQQPQYRIVAIEKKSAVGSEAKEVVGHYNPCNAKAADQIKLNQERYDYWVKVGAKASPTVAALAKKASAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CCNOB_XENLA
Sequence: MVTCSMRCTEEGLLGATLAFSSGKRKRDSVYSPGDATPGDRGEGEPKCPSVGTKKRAKYSRHRKQSLELRSCDSGVADLYETPSPSPVAPSPTHEPWDTCTPMYDGLGLQNFRDYGQDCYTFNKSLEDKFLAVNCLKNQPQIQAESRCKLISWLIPVHRHLNLGFESLCLTVNILDRFLACTPVASDCFQLVGVTSLLIASKQVETRPPRVKQLLALCCDAFSREQLCNLECIILLKLHFRLGAPTINFFLQHFSLLRVTNEESSDTELSETTKSVTVARGIAELSLADYAFNSYSPSLMAVCCLEIADRMLCHRNPIRARVSDYHESLIQECVGKIDLLVSLNQDSLHRLLPSQFAVKSINVDN
What is the function of this protein?
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation.  Acts downstream of mcidas to promote mother centriole amplification and maturation in preparation for apical docking.
What are the official names of this protein?
Cyclin-O protein B.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the apical part of cytoplasm.
Protein: CANT1_MOUSE
Sequence: MPIQPFDQREWNEPMHSLRISVGGLPVLASMTKATDPRFRPRWRVILTSFVGAALLWLLYSHHQGPVPGRPPTHNAHNWRLSQQRISHYNDTYPLSPPQRTPGGIRYRIAVIADLDTGSRAQEENTWFSYLKKGYLTLSDSGDRVSVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVIYQIEGTKAVPWVILSDGDGTVEKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVMNENPEWVKVVGHRGSVDHENWVSSYNALRAAAGIRPPGYLIHESACWSDTLQRWFFLPRRASHERYSEKDDERKGSNLLLSAAQDFRDISVRQVGTLIPTHGFSSFKFIPNTDDQIIVALKSEEDNGRIATYVMAFTLDGRFLLPETKIGTVKYEGIEFI
What is the function of this protein?
Calcium-dependent nucleotidase with a preference for UDP.  The order of activity with different substrates is UDP > GDP > IDP >> UTP > CDP = GTP = ITP.  Has very low activity towards ADP and even lower activity towards ATP.  Does not hydrolyze AMP and GMP.  Involved in proteoglycan synthesis.
What are the official names of this protein?
Soluble calcium-activated nucleotidase 1, SCAN-1, Apyrase homolog.
What is the protein family that this protein belongs to?
Belongs to the apyrase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Processed form: Secreted.
Protein: PPR96_ARATH
Sequence: MTSCVHLGIVASQSKKMSLAKRFAQLRKASPLFSLRGVYFSAASYDYREKLSRNVLLDLKLDDAVDLFGEMVQSRPLPSIVEFNKLLSAIAKMNKFDLVISLGERMQNLRISYDLYSYNILINCFCRRSQLPLALAVLGKMMKLGYEPDIVTLSSLLNGYCHGKRISEAVALVDQMFVMEYQPNTVTFNTLIHGLFLHNKASEAVALIDRMVARGCQPDLFTYGTVVNGLCKRGDIDLALSLLKKMEKGKIEADVVIYTTIIDALCNYKNVNDALNLFTEMDNKGIRPNVVTYNSLIRCLCNYGRWSDASRLLSDMIERKINPNVVTFSALIDAFVKEGKLVEAEKLYDEMIKRSIDPDIFTYSSLINGFCMHDRLDEAKHMFELMISKDCFPNVVTYNTLIKGFCKAKRVEEGMELFREMSQRGLVGNTVTYNTLIQGLFQAGDCDMAQKIFKKMVSDGVPPDIITYSILLDGLCKYGKLEKALVVFEYLQKSKMEPDIYTYNIMIEGMCKAGKVEDGWDLFCSLSLKGVKPNVIIYTTMISGFCRKGLKEEADALFREMKEDGTLPNSGTYNTLIRARLRDGDKAASAELIKEMRSCGFVGDASTISMVINMLHDGRLEKSYLEMLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g62930, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MMF2_SCHPO
Sequence: MSKVPINSSKLSCGGPYNQAVKSGGLIFCSGQAAVKDGNFVPGTIQEQTRLTIENLAEVLRVAGSSLEKLVKVNIFLTDIDDFAAMNEVYKEMLPDPMPARTTVAAGKIPLSSKGGKIEIECIAAE
What is the function of this protein?
Plays a role in the maintenance of mitochondrial DNA.
What are the official names of this protein?
Protein mmf2, mitochondrial, Maintenance of mitochondrial function 2.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: GLUQ_SHEFN
Sequence: MIPPSYIGRFAPSPSGSLHFGSLVAALGSYLRAHSQQGQWLVRIEDIDPPREVPGASDNILRTLDAYGLHWHGTVLFQQQRYQVYQDQIEAFIASDLAYYCQCTRKIIQTSGGVYDGRCGRLQPRLTHGAIRIRNHVKVDHFVDKLQGPVVVDKAFAEEDFIIKRSDGLYAYQLAVVLDDAYQGITEVVRGCDLLEASCRQISLFTQLEFTPPDWLHLPLVCAEKGFKLSKQNYAPAIDVIHPQASINAALTFLGQKAVDVDSVEVMLKQAVEQFDLSTIPAQKEIVLSTIND
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: SPKUL_DICDI
Sequence: MSLFFKSIKSKIEETLNHTPQVNLFNNSNNGGNNSNNGGNNSTPTLTKTPSTTNFPYNDYKNYTYKYVYDNTDNYNFNNNNNNNNNNNNNNNNNTKENNFKSIRESASIYKNNEEINNDDNNTIINKKKIEEEEDETNFDTSLIPKLGHEDKDELESDHYITIWGNGIRNYKNCNMSSIGFSEMYNQQKIVLISTGAIHSSFITDQGNLYTFGDGLLGKLGHGNLESYSSPKLVEFFQTKPSLRVVSIANGGKHSLALTICGKVYSWGGNDSCQLGLGNGSSSSYYSLPQLINFNISYNNNNNNNNNNSTNNNNNNNNDGAQQQFSLSQNSSSNNNKIKIVKLSCGTNRSAVITDKGLLFTFGRGDHGRLGLGEQSLLMQSTPKLVQSLQGHFIIDMSSGGGHSLVLTNKGLVFSFGRNDQGQLGIGCFSNQQTIPKQIQWFQTSQQQQQQPINIIKVSAGGYHSIAISDNNDTYAWGRSDYGVLGTSIDVQGDRNLPVLINSNSVVVDNVKFIDVSSGFQHNVAMSIDGSLYSWGCNAGQRLGFKSDENQLTPKKCFINSKDSKPLLFTCGEIITIIVEKRFKEPIIKTELQLPSSTQSQQQTELSLPSSVNSSSDSNFNKSIIDNSSTTTIIKQTNNNIKSTTTTIITRPSSPTPSFLSLANEGKDLLNSTQSNFIEWMTLISKSKGLLNLIQMKATSSLPNLGLSIEKKNKDFDDINRQLKLLVNSNLSLSPLPDNIQSEIDRLVLSRNQLGLGLVSEYQTSIDYWLEIKQQKDLTFLNLSKLLNLSTITTTTTSNTTTTTTATTTTTTTTTTNLINKKVLVHQDEKQQQREKSETELEEEQDEEEEDSEIKNGTLTAIEIQQQSFYLVERLNQGLGNFCNNIMDSTTMVQPLTTATASSTTATATATTTTANTTNSSGIINKNFGESLRLSMEEIQLIVLETQKYAIKYHSLLSQQLQQCDDLINIHRGKLVEVQDFLNKSKLAQSLLEQREKLKSDYRFCKRNSIELSKKIEVIELDYDQNLCDDDDNNHENNSVNNNSNNNNNNNNNNNNNNNNNNNNNNNIDNNINSNSINDSSNNNNNNNNIEKLKNELIKLKKDEQKLLSNQQEINELIIEILDKYVPEFKIKLRANDKISSRIKDTGLLVTDRKFQHYDIIKTLSTHPHNVYLANFNDQLVVLKEFGIGDAFGKQIFERQVSLLKQMNHKCIMPIQAVFYDRNAFMQMEYISGGNLLDWCRNNNNDNENNKRRQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDGTPVISDFDLSKDISANVNVTVFNINGGTELYKAPEMKEQNVKGSYSTDIWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGNENDNNNNNNFLIIREPFLLPEENNLPLPANHSDQRLISLLSSIFQRNPKLRPTAHQIAVHPYFVTSLVEDLLSSRTLIDCREKIAAFRAHISSLSEMAEEMSESLQLTVRREHLVLDFFQFFFKKIESNKLFCRLEVSFQGEKGLDLGGLSSEMYSLLFSDNQIIDNSNNSNNSVSYSIPKNSLFSKKFNLFENSGTESPFYLLNSNDLFNNNNNNNEENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEENPLLILKNEFTIFKILGKIFLKSIIDGKPIPDCFPTSFFKYLLGVKVNLRDLEIYDPQLAQSFKKVLVLDNIEEYLSTTFEGLIEGGESIPVTDLNKEEFIQRNIERVLVGCRQSKLEAFKSGFMSIDSLNAHFALFSPTELQLLMCGNTLVDSSVLQKNFKFIGFPDTSSTPKDFRRAVDEMNQDEIRLFLRFVTGMVALPLSGFEKSISIIQVPLSQKLPCAHTCSYQLDLPDYNDFDTTKKKLIKMLEYVDGFAFI
What are the official names of this protein?
Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: NRDR_CLOB1
Sequence: MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREYFDRNKIVNGLMKACQKRPVSRKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKIDEVSYVRFASVYRQFKDINTFMEEIKNLMDKN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PROF_CHEAL
Sequence: MSWQTYVDDHLMCDIEGNHLSSAAILGHDGTVWAQSPSFPQLKPEEVSAIMKDFNEPGSLAPTGLHLGGTKYMVIQGEPGDVIRGKKGPGGVTIKKTNQALIIGIYGEPMTPGQCNMVVERIGDYLVEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Minor pollen allergen Che a 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MYC_PIG
Sequence: MDFLRIVENPAAAMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPIPARGHGGYSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKPCASPDSTAFSPSSDSLLSSAESSPRGSPEPLALHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQPPAKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPSAKRAKLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFARRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLVSEKDVLRKRREQLKLKLEQLRNSCP
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: YE1A_METJA
Sequence: MYLIWIIGGGQKDLTNKILDEIKKLYEQLDEIKDKNINSSNVQLNEFMRQNVNMLKELNQKIDKYLENNNEILKEMEKYVKEDIEHKNRMERKLKQISMLLLIVIIAIGLTISYMVILNNEYLSTQLFNYIQIAIQYLKSLLSNY
What are the official names of this protein?
Uncharacterized protein MJ1417.1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL13_LEGPA
Sequence: MKTFSAKGNEVKRDWFVVDASEKVLGRLATEIARRLRGKHKAEYTPHVDTGDYIIVTNAEKVVVTGRKFKNKMYHHHTGFPGGIKSASFEKLQDKNPTKIIELAVKGMLPKNPLGREMYRKLKVYAGSEHPHTAQQPKQLEIEE
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TGT_THISH
Sequence: MKFELIANDGAARRGRLSFPRGTVETPAFMPVGTYGTVKAMTPEELEGIGAEIILGNTFHLMLRPGTEVIQLHGDLHDFMHWEKPILTDSGGFQVFSLADLRKITEEGVKFRSPVDGSEILLTPERSMDVQRALGSDIVMIFDECTPYPATEDQARESMELSLRWAARSKVAHGDSPSALFGIVQGGMYPALRSRSLEGLVDVGFDGYAIGGLSVGEGMEERHHVLDHLMPEMPAERPRYLMGVGKPEDIVEAVRRGVDMFDCVIPTRNARNGFLYTREGVMRIRNSRFRTDTGPIDESCDCYTCRNYSRAYLKHLDKCNEILGARLNTIHNLHYYQTLMRELRGAIAEGRLEAWVAEFYGRRSQAVPSVP
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: GUAA_BRUMB
Sequence: MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEVQQVVEMFREHYNLPLILVDASDRFIGALEGESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NUSB_XANAC
Sequence: MSKPGGHSRHGRRDGIDPVLRSRARRRALQAVYAWQISGGFAKQVIAQFAHEQAHEVADLAYFENLVEGVLSNRAELDTALTPYLDRSVEEVDAIERAVLRLAAYELLYRQDVPYRVVINEAIETAKRFGSEHGHTYVNGVLDRAAVEWRKVESGASGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.