PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_PSE14
Sequence: MNKAISDLSSHTPMMQQYWKLKNQHLDQLMFYRMGDFYEIFYEDAKKAAKLLDITLTARGQSAGQSIPMCGIPYHAAEGYLAKLVKLGESVVICEQIGDPATSKGPVDRQVVRIITPGTISDEALLDERRDNLIAAVLGDERLFGLAVLDITSGNFSVLEIKGWENLLAELERINPVELLIPDDWPQGLPAEKRRGARRRAPWDFERDSAHKSLCQQFSTQDLKGFGCENLTLAIGAAGCLLSYAKETQRTALPHLRSLRHERLDDTVILDAASRRNLELDTNLSGGRDNTLQSVMDRCQTAMGTRLLTRWLNRPLRDLTILQARQTSITCFLERYRFENLQPQLKEIGDIERILARIGLRNARPRDLARLRDALSALPELQQAMTDLEAPHLQQLAQTASTYPELADLLQRAIIDNPPAVIRDGGVLKTGYDAELDDLQSLSENAGQFLIDLEAREKARTGLANLKVGYNRVHGYFIELPSKQAEQAPADYIRRQTLKGAERFITPELKEFEDKALSAKSRALAREKMLYEALLEDLIGHLAPLQDTAAALAELDVLSNLAERALNLDLNCPRFVAEPCMRIEQGRHPVVEQVLSTPFVANDLALDDSTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAASCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATDKSLVLMDEVGRGTSTFDGLSLAWAAAECLAQLRAYTLFATHYFELTVLPESEPLVSNVHLNATEHNERIVFLHRVLPGPASQSYGLAVAQLAGVPGKVISRAKEHLQRLETTSLPHEQPRAKPGKPAVPQQSDMFASLPHPVLDELSKVKVDDMTPRQALDLLYTLQTRL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: AIM9_YEAS2
Sequence: MIRYTVAGHSRRCVVGASKRVGAIKCITVAATKRFISNKSNEVFTKLTNDNDPKRDAFFKYTWGSWLKNDKQEKEKRFTKFSIEGLNRILNDIYIQSNEMAKAPDGKILPPVFNKNLTVSLVNNVVPKNIGKINPNEKVQVTTLSSIHEGKHHRIYKVDTNLNKAFILRIPYPLENENTLSYRIRSEVATMDFADLKLGIKVPKIFCYGVNSLNPVRQPFVLQEFIEGELLMKDWDPLIEDGSSNQKKYDNVIKQVSDFQSKLVSLKLNAFGSIYFNNDLKDGNEKEFVKEDIYDGETNPDLQNRWKIGPSVERCLWRHKSHLDFHKQMKPFLGPWPKKSPMDIIKNTGLLEAENAKTRIAMKEAGSSAELMYPRTLKEQITTYENLAKIAPDLFNVKTKAIPNMQELLSPRLFHPDLDPMNIIVNKEAQEAYLLDFEGACTKPFILQNSPQFIAYDGPKIYDLKEDITDFDKLSEAEKVQYQFMYKRTRNQHQWEKKLNDNNPKLITAVAPPVKLLRSPYIAAVERKTEEEYLLIDESLLQLKEVWDIFAQNDLVNQKKFPLNYSKEDIERHVEDLQKLHEKLISTPFAATQGWIPQDMFDQLLNSGSIVKQENGDYTVKQPEATK
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RRF_SALTY
Sequence: MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEVQKMTDAAIKKVDAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3737_BACCQ
Sequence: MASETVSNHQEKALALLQADAEKILRLIKVQMDHLTMPQCPLYEEVLDTQMFGLSREVDFAVRLGLIAEEQGKAMLGELERELSALHEAFTNKQQ
What are the official names of this protein?
UPF0358 protein BCQ_3737.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: XRCC4_CRIGR
Sequence: MERKVSRISLASEPNITYFLQVSWEETVGSGFVITLTDGHSAWTATVSESEISQEADDMAMEKEKYADELRKALVSGSGSDTYKFIFSRESCHFSLEKELKDVSFRLGSFNLDKVPNSTEVIRELICYCLDTIAEKQAKNEHLQKENDRLLRDWNDVQGRFEKCVIAKEALEADLYQRFILVLNEKKTKIRSLHKLLDEIQQLEKNLKPERETKCSEKTTDQDAIYDGSTDEEAGASVLAEAAVCKEDSLFSSPDVTDIAPSRKRRHHMQKNLGTEPKMAPQEQQLQGKERLASSLPHTLKEEHEHTSAGNMSLETLRNSSPEDIFD
What is the function of this protein?
Acts as an activator of the phospholipid scramblase activity of XKR4.  This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell surface.
What are the official names of this protein?
DNA repair protein XRCC4, X-ray repair cross-complementing protein 4.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XRCC4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to site of double-strand breaks. SUBCELLULAR LOCATION: [Protein XRCC4, C-terminus]: Cytoplasm. Note=Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3).
Protein: RPOC_PETMO
Sequence: MANVSSFQRKIAKIKIGIASPQSILEASNGEVKKPETLNHRTGKPEKDGLFCEKIFGPVKDYECACGKYKGKKYEGTVCERCGVKVESKEARRRKIGHIELATPISHIWYLKSSPSILSIILNIGVKDLENIIYYGSKRVIERAYLTLPGPENENLGYLPGEILYQREYEIYDEYLDLRVEPAVKIVSVKGMPVADIDGKVEIKSELTHTERELNWIIIRDDTGVERKYPVFEGSSIMVENGQEVEKGTPLADRFLFEEDYLTQKEYSLFLEYYPGSIEVERDIERDTPIVVITDIDKRFAKRIDKKIGDILLEDEARAYEEVMKVLNSKIKEERENVIDKELVSEIEFPEKKFEKGTKITQEVLNELQEFGVKDLVAKEEDGTEKIFQINRYEKFEYGYGAEAIQKLLTKIDLEVLKARLESELEKLDRKSQKSVKILRRLKLVKDFIKSGNQPEWLITNIIPVIPPDLRPLIQIDGGRFAATDLNDLYRKVINRNNRLRKLLEMEAPEIIVRNEKRILQQAVDSLFYNGRVGKPMTDRNRRPLRSLTDLLKGKKGRFRRNLLGKRVDYSGRAVIAVGPDLKIHECGLPKKMALELFKPFVLAELLRDSNVASKSARKFKKTIIEKEMPEAWEVLEEVIKGHPVLLNRAPTLHRVSIQAFIPKLIEGNAIRLHPLVCPPFNADFDGDQMAIHIPLSNIAQAESKFLMLSRYNIISPANGKPLSMPGKDIIAGAYYLTMHEDEKFKNLKVPTKVSELGKNGYVKHIFSEDLEATYAYEYLKIVDSDIYLQDGKLIWKKSDLPLHEPVAFRYKDGSILKTTIGKIIFNEEVPEDLRDYTQKMDKKNLKELIFNTFEKHGIDRTADLLDSIKDFGFHYATLSGLTISIRDVLVSPKREELIEESKGEVLRIESLYEEGYLTDNERYKEIIKIWESATAKVTEETAKTYRKYTFNPIWMMIESGARGNIDQLKQLAGMRGLMADPSGKIIEVPITSNFKNGLSELEFFTSTHGSRKGSADTALRTSTAGYLTRRLVDVAQSITITEEDCGTDKGIEARELWADDSKIENLSDFLFGRVLAKDVLDPETKEVIFNPQADKKYERGIILKEKDAQFLANYVKEIPVSKEKTIKIEDMPKDSYLESLEDVQVEGKVLIKKGEEITEEAIEEAFLHGIQKLDVKEYTAVDYVYSGEDLKVEIDGKTVTLLKYQERIDLKVSKVLEKHGIKTVTVRPSIFIRSPLTCESENGLCAKCYGMDLSNYKLVNRGEAVGIIAAQSIGEPGTQLTMRTFHTGGIATTSDITQGLPRAEELFEARKKTKGPEGEFSKTKGIVRAIERDTENKRGRRLKIIIENSDGELESYEADYRTKAVVEEGDKVLAGQRLTTGNIKPRNILKELGVGPLANYLLSEIKKIYAEQGVDIHDKHFEIIIRQMINKVEIIDGGDTDFMPGDLVSYGKVQKINEEILEENSYITENRELVVGKKLAKRVIIPAEDEEEEEDKIFEQGTEITEEILNQIIETNIKEIEVYEEYKEITTEEGKTHLVGTSKKYLINPKDTIKYERRLLRITKASLEREGWLSAASFQQTVQILTEAAIEGKVDRLKGLKENVIVGQPIPAGTGLKLYADQNYEVVQPEKEAEAAQEKSVG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NADK_LACJO
Sequence: MKVALVYNDKVETLAVVKALEKLLNARKIEIDPENPDVVITIGGDGTLISGFHKYQNLVDKIRFIGVHTGHLGFYTDWRNFEINKMVDNLTKKQPSSASYPLLELIITTGAGEKKKLLALNEATIKRVSKTLKADVYIRDQFFESFKGDGLCVSTPTGSTAYSKSLGGAVIHPRLKALQMTEIASINNRVFRTLSSPIVIAPDEWITIKPETGSDDHYVVTFDGYEFNHKHIKKIEYRISQHVIRFDKYQHTHFWNRVEDAFIGQPKDKQ
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMA_YERPE
Sequence: MAMKKLLIASLLFGSATVYGADGFVVNDIHFEGLQRVAVGAALLNMPVRVGDTVSDDDIGKTIRALFATGNFEDVRVLRDGNTLIVQVKERPTIASITFSGNKAVKEDMLKQNLEASGVRVGEALDRTTISNIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFTEGVSAKIQQINIVGNHSFTTDELISRFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSFYLDRGYARFNIDSTQVSLTPDKKGIYVTINITEGPQFKLNSVIVSGNLAGHQSEAEKLTKIEPGELFNGSKVTRMEDDIKKMLGRYGYAYPRVVTQPEINDDDKTVKLHINVDAGNRFYVRHIRFEGNDTSKDSVLRREMRQMEGAWLGNDQVEAGKERLNRLGYFETVDVETQRVPGAADLVDVTYKVKERNTGSLNFGIGYGTESGVSFQVGVQQDNWLGTGNTVGINGTKNDYQTYAEFTLMDPYFTVDGVSLGGRIFYNDFKADNADLSGYTNSSYGADGTLGFPINENNSLRVGVGYVHNDLSDMLPQVAMWRYLESVGERPGYDGREGFTTDDFTLNLGWTYNNLDRGFFPTSGVKSSVNTKITVPGSDNEFYKVTFDTSAYQPLNEDRSWVLLGRGRLGYGDGIGSKEMPFYENFYAGGSSTVRGFRSNNIGPKAAYYANGGATVTNSTDAVGGNAMAVASIELITPTPFISEKYSNSVRTSIFIDSGTVWDTNWENTAKTRAAGIPDYGKASNIRVSAGVALQWMSPLGPLVFSYAKPVKDYEGDKSEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SUCC_STAAM
Sequence: MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YDCH_ECOLI
Sequence: MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGYNAEVVRMKKQKLQLKDEMLKILQQESVKEV
What are the official names of this protein?
Uncharacterized protein YdcH.
Protein: COQ6_HUMAN
Sequence: MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACALGYDIHFHDKKILLLEAGPKKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPFPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK
What is the function of this protein?
FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis.  Catalyzes the hydroxylation of 3-hexaprenyl-4-hydroxybenzoic acid (HHB) to 3-hexaprenyl-4,5-dihydroxybenzoic acid (DHHB).  The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6 (By similarity).  Is able to perform the deamination reaction at C4 of 3-hexaprenyl-4-amino-5-hydroxybenzoic acid (HHAB) to produce DHHB when expressed in yeast cells lacking COQ9, even if utilization of para-aminobenzoic acid (pABA) involving C4-deamination seems not to occur in bacteria, plants and mammals, where only C5 hydroxylation of HHB has been shown (PubMed:26260787).
What are the official names of this protein?
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, Coenzyme Q10 monooxygenase 6.
What is the protein family that this protein belongs to?
Belongs to the UbiH/COQ6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Golgi apparatus. Cell projection. Note=Localizes to cell processes and Golgi apparatus in podocytes.
Protein: PDXAL_PSEAE
Sequence: MNAPSLPRLAMVLGDPAGIGPELIARLLADTEVREKAHIVLIADEAEMRRGMRIAGCEFPYRRIDALETLDFADATPLLHPWLSQGGDEFPRSEASAVGGRYSLETLALALELTRSGRTDAILFGPLNKTSLHMAGMDHSDELHWFAERLGFGGPFCEFNVLDDLWTSRVTSHVALAEVPGLLSQERVGEAIRLIDDALRRSGLARPRIGVCGLNPHNGDNGSFGREELDIIAPAVQKAREQGIAADGPYPADTIFLKVQGDARAFDAVVTMYHDQGQIAIKLMGFSRGVTVQGGLPIPIATPAHGTAFDIAGQGRADVGATRQAFEIACRMGRHKA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
Putative 4-hydroxythreonine-4-phosphate dehydrogenase 2, 4-(phosphohydroxy)-L-threonine dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y144_STAES
Sequence: MRYLKRITIYISLLILVSGCGNNKEAEIKQNFNKTLSMYPIKNLENFYDKEGFRDEEFDKDDKGTWIINSKMIVEPKGKDMEARGMVLHINRNTRTTKGDFIIKRITEDNKGIPDVKDKKYPVKMENNKIIPTKQIKDKKLKKEIENFKFFVQYGNFKNLKHYKDGEISYNPNVPSYSAKYQLSNNGYNVKQLRKRYDIPTNQAPKLLLKGTGDLKGSSVGYNHLEFTFVENKKENIYFTDSINFNPSRGD
What are the official names of this protein?
Uncharacterized lipoprotein SE_0144.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: YR853_MIMIV
Sequence: MYEDAIDFDDPYLFHSVISPQLNSGLITPRYVLDKVIDKYNKSNTDLLYEVEGYIRQLVWREYSRMLYRYIRKDMMKNYFGNKNRISEIWYTGNTGIEPVDLAISSAFQYGLSTSNFFFIFLYIFTIKI
What are the official names of this protein?
Uncharacterized protein R853.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOG_BLOFL
Sequence: MMIPIYIEEKKYMVEDTKNVLEVCLSLGFNVPYFCWHPALGSIGSCRQCAVKLYDNLHCVPDSKHINFGRLVMSCMTPVIKDMYISLFDKELQEFRKNILELLMVNHPHDCPVCEEGGNCHLQDMAVMVEHTYRRYRFTKRTHYNQYLGPFITHEMNRCITCYRCVRYYKDYAGGNDLGVFGVHDNIYFGRVQDGILQSEFSGNLVEICPTGVFTDKTQSKNYARKWDITFAPSICHQCSVGCNIILGERYGKLCRVENRYNSKVNGYFLCDRGRFGCNYIHIKNRPQKLLKKQNNCGYIEINAVDAVQDCVNILKSSNKIIGIGSTRASIESNFALRNLVGADNFYSGMSFFEQERLSLIFEILRNSGIYIPSVCDIENYDAILILGEDVTQTSARIALAIRQAVRSKSDHMAKYVGIYKWQSLAVTNFAQDAKYPLFITGIDKTKLDDIAMYTYYDSVQNQARFGFSIAYAVDNQVSFVKDFNLNGLDITKLDLVVEKLMCARKPLIVSGSNSGSKELIIAAVNIAYALKRKKSDVGLVLVDHDVNSIGLSMMTSKSVDDVFNTLSDTNNGNAVFNTVIILENDLYRHASVAKINKMLSNINYLIVLDHQYNIIQDKADLIFPVSSFAESDGTVINYEGRAQRFFKLYNPQNYDKNSDILESWKWLYLIHDTYVNCTRVKAVNIDYIIDSIACCFPELKKIKYASPKSNFRVHGQKLAQSTHRYSGRTSINANVNVHETSTPINDNTMFTFSMEGNSGNYSKKCSYNQIPFVWAPGWNSPQAWNKFQDQIGGNLYPSDPGVLLFDTGQENKCIDDNLYKSINWLKFASNSLNISKYTNKWIVAPYWHLFGSEETSQNVECIKNCMLNPYAMLNILDAKYINIQENMYIKFTCMDQVLCLPVKFSMDLPKKHIGLPMGFPGIPVFFSGMYVSNIEMMEAP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G, NUO7.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: CYSI_VIBCM
Sequence: MSANQNPSVQEVLGEVLGPWSDNERLKRESHFLRGTIEQDLQDRITGGFTADNFQLIRFHGMYQQDDRDIRAERSKQKLEPLHNVMLRARMPGGIITPHQWLAIDKFATEHTLYGSIRLTTRQTFQFHGVLKPNIKLMHQTLNSIGIDSIATAGDVNRNVLCTSNPVESELHLQAYEWAKKISEHLLPKTRAYAEIWLDGEKIEGPDEEPILGSNYLPRKFKTTVVIPPHNDVDVHANDLNFVAIGENGQLVGFNVLVGGGLAMTHGDTSTYPRRADDFGFIPLEKTLEVAAAVVSTQRDWGNRSNRKNAKTKYTLDRVGVEVFKAEVEKRAGITFAPSRAYEFTSRGDRIGWVEGIDGKHHLTLFIENGRILDFPGKPLKTGVAEIAKVHQGDFRMTANQNLIVAGVPADQKPHIEQLAREHGLIDDGVSEQRINSMACVAFPTCPLAMAEAERFLPSFVTEVEGILAKHALPKEENIILRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRNGTRIPKMYKENITDTQILQEIDELVGRWASERLDGEGFGDFTIRAGIIEEVIISKRDFYA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: BIOF_METPP
Sequence: MPPDIHDVFGSALAALDTQQLRRHRRVVSALDGAMVQADTQPRLAFAGNDYLGLSQHPALIEAARQGAARYGVGATASPLICGHSPAHEALEQELARFVGLPRALYFYAGYAANAGAIPALVERGDALISDALNHACLIDGARLSRADLTVYPHNDLAALERALVAARGARRRLVVADAVFSMDGDLAPLPEMLALCERHDAWLYVDDAHGFGVLGEGGRGSLSHWRVPTDAMSSRLIYMATLGKAAGVAGAFIAGAPAVIEWLVQKARTFFFATGAPPMIAEALRASLQVIESEGWRRERLLQLRTRLACGLAALPWPAPASQSAIQPLLLGDNGTALRVMAALDAQGIWVPAIRPPTVPDGTARLRISMSAAHTPDDVDRLCAALLAASARPPV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MASY_ORYSJ
Sequence: MATNAAAPPCPCYDTPEGVDILGRYDPEFAAILTRDSLAFVAGLQREFRGAVRYAMERRREAQRRYDAGELPRFDPATRPVREAGGWACAPVPPAIADRTVEITGPAEPRKMVINALNSGAKVFMADFEDALSPTWENLMRGQVNLRDAVAGTITYRDAARGREYRLGDRPATLFVRPRGWHLPEAHVLVDGEPAIGCLVDFGLYFFHSHAAFRSGQGADFGPFFYLPKMEHSREARIWKGVFERAEKEAGIGRGSIRATVLVETLPAVFQMEEILHELRDHSAGLNCGRWDYIFSYVKTFRARPDRLLPDRALVGMAQHFMRSYSHLLIQTCHRRGVHAMGGMAAQIPIKDDAAANEAALELVRKDKLREVRAGHDGTWAAHPGLIPAIREVFEGHLGGRPNQIDAAAGDAARAGVAVTEEDLLQPPRGARTVEGLRHNTRVGVQYVAAWLSGSGSVPLYNLMEDAATAEISRVQNWQWLRHGAVLDAGGVEVRATPELLARVVEVEMARVEAEVGAERFRRGRYAEAGRIFSRQCTAPELDDFLTLDAYNLIVVHHPGASSPCKL
What are the official names of this protein?
Malate synthase.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: ZC3HD_HUMAN
Sequence: MSKIRRKVTVENTKTISDSTSRRPSVFERLGPSTGSTAETQCRNWLKTGNCLYGNTCRFVHGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEKMPDPLDVIDVDWSGLMPKHPKEPREPGAALLKFTPGAVMLRVGISKKLAGSELFAKVKETCQRLLEKPKDADNLFEHELGALNMAALLRKEERASLLSNLGPCCKALCFRRDSAIRKQLVKNEKGTIKQAYTSAPMVDNELLRLSLRLFKRKTTCHAPGHEKTEDNKLSQSSIQQELCVS
What is the function of this protein?
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755).  Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR (By similarity).  Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (By similarity).  In the WMM complex, anchors component of the MACOM subcomplex in the nucleus (By similarity).  Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B) (By similarity).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 13.
What is the protein family that this protein belongs to?
Belongs to the ZC3H13 family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm.
Protein: GLGA_RHOPS
Sequence: MTTLTALSVASEIFPLIKTGGLADVTGALPAAVKAHGVAMRTLVPGYPAVLGGIEDPQQVHSFTEFFGGSARLLAARCDELELLVLDAPHLYVRPGNPYVGPDAKDWPDNALRFAALAQAGAWIGQGLLPGYAPDILHAHDWQTGLLPAYLRYSGRPAPKCVFTIHNLAYQGQFPSELLARIGLPERAFSLDGVEYYGGIGYLKAGLQLADRITTVSPSYALEIQGSEAGMGLEGLLRLRAGQLSGILNGVDTKVWDPSADQLIPATYDVETIGARARNKQALQARFGLRAESGALLFGVISRLSWQKGLDMLLEVLPGMLADGAQLALLGAGDAPLEAGFRDAALKYPGQVGAVIGYDEALAHQIQAGADALLVPSRFEPCGLTQLCALRYGAVPVVARVGGLADTVVDANEMAIATGVATGVQFSPVTADMLTAALTKTRALYADHATWRNLQINGMTTDVSWKNPAQHYAKLYRELVDA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: DPO3B_HALH5
Sequence: MHFVIDRDIFVQNVNHVSKAVSSRTTIPILTGIKIVADHEGVTLTGSDSDISIETFIPLEEGDRQNVEVKQEGSIVLQAKVFAEIVKKLPEQEIEIHVQDSFVTTIRSGSSVFNLNGLDPDEYPRLPVLEEDHVFRLPQKILKDIIRQTVFAVSTQETRPVLTGVNFEIEDGILTCTATDSHRLAMRKVPVEKNDDELQFSNVVIPGKSLNELSKILDENEELLDIVVTENQTLFKLKNMLFFSRLLEGKYPVTKNMIPKEAKTSFAVHTKAFLQTLERALLLSREGKNQVINLKTLGDGVVEVTAITPEIGKVTENVATQGLEGEELRISFNGKNVIDALKVVDSESIHIAFTGAMSPFVLSPTDHDQSLHLFSPVRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
Protein: RSU1_BOVIN
Sequence: MSKSLKKLVEESREKNQPEVDMSDRGISNMLDINGLFTLSHITQLVLSHNKLTTVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLNENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQIFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNK
What is the function of this protein?
Potentially plays a role in the Ras signal transduction pathway.  Capable of suppressing v-Ras transformation in vitro (By similarity).
What are the official names of this protein?
Ras suppressor protein 1, Rsu-1.
Protein: DAPA_LISMO
Sequence: MDLGKVITAMVTPIHPEKDKVCKKRIHHLVNHLIKNGSDGLVIAGTTGESPTLSHDEKIKLFRQVIETNDGRAKLIAGTGSNNTAETIAFTKEVATLGGMDAVLIVAPYYNKPNQDGLYAHFAAVAEASDLPVVIYNIPGRSVVNIEPETIIRLAKLPNIVGVKESSGNLDNISKIIAETSDDFQVYSGDDSLTLPILAVGGNGVISVASHIVGNEMQEMIQAFERGEVQKAAQIHRELLPLMNGLFSVPNPAPTKYLLNQQGISVGPVRLPLVDLNAEQGTKLQAILEGLSK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.