PharMolix/UniProtQA huggingface dataset:
Protein: LANA1_HHV8P
Sequence: MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
What is the function of this protein?
Multifunctional protein that plays a role in the replication and long-term persistence of the viral episomal genome in dividing cells.  Binds to mitotic chromosomes via its N-terminal region and to a 16-bp imperfect palindrome within the origin of replication (oriP) located in the viral terminal repeat (TR) through its C-terminal.  Tethers viral episomes to chromosomes during mitosis.  Plays a critical role in the shutdown of lytic gene expression during the early stage of infection by interacting with host TRIM28.  Plays also a role in the repression of host NF-kappa-B activity upon TNF-alpha stimulation by promoting the proteasomal degradation of host RELA (PubMed:21697472).  Promotes nuclear localization and cleavage of host STAT6 leading to constitutive activation of the IL13/STAT6 signaling pathway to promote viral latency (PubMed:28099521).  Interacts with and modulates the histone methyltransferase MLL1 complex activity, leading to its recruitment on viral DNA terminal repeats changing the dynamic of histone H3 methylated 'Lys-4'(H3K4me) profile during the initial hours following infection (PubMed:34850113).
What are the official names of this protein?
Protein LANA1.
What are the subcellular locations of this protein?
Host nucleus. Note=Colocalizes with viral episomes on host chromosomes.
Protein: UL87_HCMVM
Sequence: MAGAAPRRLGCDALIVVGGSAMPRRVLHVPVHVRACNLTQELSTGEDARFCRPRPVNVERVRAVFAALYRACPIHVRTEPERVKLVLGRLLLGPVAVPCFCDGEVEGHGEHLVPTTQFCRGPLLYVHRRCCCGSVTAGRALSYHVLENHVATHVLRGLLSLTEWNRELPSLFCDCPGGGGASGTEERYAMACLPRDLSLHLDDYPYLMVEIGRVLSVSEVDDYVTAVSGYLGEAAAPRIQVHYKLLFGLNVRPQAPCALDATRDFFLLELQKLWLGVEYHHEVTSEFFGRVLAQLHRDRARVMMALRLPEQTVCHLSTFVLSRFKRQVLYFKLQVSYGKCRTGHADRSGGGGNGGNQGHHNLLCYRRLSVTFADTDTVWRNLFYVYYELARDLGSHGTENRPVNRGYGVSCAPRTSRLSPSESTVVSANGHALSSTALPTTSAGHKLSLPRDPAADRVRRYVCIISRLMYARYGERWRKHRQRRSETGEEEEEETLESGETDATPPFDFTGQQLRRAYQEHRRRKHLAVQRYAPCRRKLIGGMEFAEVTGVSLDRIAVNAFNTNRVINMKAALSSIAASGLGVRAPRLPKNMTHSFVMYKHTFKEPACTVSTFVSNDAVYINSLNVNIRGSYPEFLYSLGVYRLHVNIDHFFLPAVVCNSNSSLDVHGLEDQAVIRSERSKVYWTTNFPCMISHTNNVNVGWFKAATAIVPRVSGADLEAILLKELSCIKNMRDVCIDYGLHRVFTQLELRNSYQIPFLAKQLVLFLRACLLKLHGREKRLQLDRLVFEAAQRGLFDYSKNLTAHTKIKHTCALIGSRLANNVPKILARNKKVKLDHLGRNANVLTVCRHVEAHKIPRTRLKVLVEVLGVLQSISGTPHTREVIHQTLFRLCSAAAATSGLCSSPPPLCVSSSSSVPSVPTSVSVDGSSEPTSPRVRFASR
What is the function of this protein?
Functions concordantly with UL87 to initiate transcription from over half of all active viral promoters in late infection, without affecting host transcription.  Acts on and binds to viral early-late and late kinetic-class promoters.
What are the official names of this protein?
Uncharacterized protein UL87.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL87 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CHEA_BACSU
Sequence: MDMNQYLDVFIDESKEHLQTCNEKLLLLEKDPTDLQLVHDIFRAAHTLKGMSATMGYTDLAHLTHLLENVLDAIRNGDMEVTSDWLDILFEALDHLETMVQSIIDGGDGKRDISEVSAKLDVNGAHAESAASAEPAEAQSSASDWEYDEFERTVIQEAEEQGFKRYEIKISLNENCMLKAVRVYMVFEKLNEVGEVAKTIPSAEVLETEDFGTDFQVCFLTHQSAEDIEQLINGVSEIEHVEVIQGAPLTSAEKPEESKQEDSPAAAVPAKQEKQKQPAKNDEQAKHSAGGSKTIRVNIDRLDSLMNLFEELVIDRGRLEQIAKELEHNELTETVERMTRISGDLQSIILNMRMVPVETVFNRFPRMIRQLQKELNKKIELSIIGAETELDRTVIDEIGDPLVHLIRNSIDHGIEAPETRLQKGKPESGKVVLKAYHSGNHVFIEVEDDGAGLNRKKILEKALERGVITEKEAETLEDNQIYELIFAPGFSTADQISDISGRGVGLDVVKNKLESLGGSVSVKSAEGQGSLFSIQLPLTLSIISVLLIKLEEETFAIPISSIIETAVIDRKDILQTHDREVIDFRGHIVPVVYLKEEFKIEDTRKDAEQLHIIVVKKGDKPTAFVVDSFIGQQEVVLKSLGDYLTNVFAISGATILGDGEVALIIDCNALII
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheA is autophosphorylated; it can transfer its phosphate group to CheB, CheY or CheV.
What are the official names of this protein?
Chemotaxis protein CheA.
What are the subcellular locations of this protein?
Membrane. Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions.
Protein: Y1295_STAAN
Sequence: MSETLNQIKESFIEYLLFQYRFKSRIAVWVLNYIKVNEAKLANIHFVDTKINHHETLEIAEVGSHASAIQFTKRNIKLMNTNEIFDYIANHNCAFDIQIHFANVSKREQRLDDLIVAQLTESPSYQTYLHDLNSMAIDRHKHALLIDYLLHNIDLSLQMNEKQRFYQLTQILNTLKLVNKHNQFEDLADDD
What are the official names of this protein?
UPF0302 protein SA1295.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: NMU_CANLF
Sequence: FRLDEEFQGPIASQVRRQFLFRPRN
What is the function of this protein?
Stimulates uterine smooth muscle contraction and causes selective vasoconstriction.
What are the official names of this protein?
Neuromedin-U-25, NmU-25.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: YADU_SALTY
Sequence: MKIIRTLFLLLIAVYGSSVVAKPMLKATFSSTTMYYGIGPNSDKSIVAEVTIATPEGVYYGSWNLSGHRKGETLTADSWSGPEPAPKVVLKDFDNTVSRSACKNLPSNWRGCGSFTLEITVQSDDYGCPWLASSHIVATTFITNETYSPPDTRSSVCPKVPVDTFDISWDANVSKQKTTLMLDATGGTVNRTLHTYLMEGGKLCDGSKFDNRGAYCRFVSSGITLNVLGCDQSSVTTSAVDHPITDVELHDINVAVNTRNIGSGQFTSTCSFQYIIDEL
What are the official names of this protein?
Uncharacterized protein YadU.
What is the protein family that this protein belongs to?
To E.coli YfcO.
Protein: Y1087_AERPE
Sequence: MSYEYDDELEEIRRRKMLELQRRLEEERRREEEQARLRAQKDAILRRLLTSKARERLANLRLVRPEIAEAAENAVIQLVQTGRITPPVDDDTLVQILLELDRSTRRDFEIRIKRK
What are the official names of this protein?
DNA-binding protein APE_1087b.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: ATPA_STAHJ
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDCMAGELVEFSNGVLGLAQNLEESNVGVVILGPYTEITEGDEVRRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEQKATGVMARKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIGIDTILNQKGLDTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVSASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTARKLERGKRTVEVLKQDQNKPLPVENQVLIIYALTKGYLDDIPVEDITRFEDELNSWTKSNGSDLLNEIRETGGLPSDDKFEATINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PA2V_MEIAT
Sequence: MAACHRILLLLSVAVASGAAQKPPLTKRGLLEFGGIITCSTGRSPLSYVMYGCYCGLGGKGWPRDKADCCHEHDCCYGEAETLGCQTKTDQYRWKCEDKKVECDDLNDKCEKFLCKCDRDAAKCLEKAPYNQKYLFWPSFMCGSEEPKCSIY
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2, PLA2, Phosphatidylcholine 2-acylhydrolase 10.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y280_GLAP5
Sequence: MLAIISPAKTLDFETKIDGFVFSQPELTAYSQQLIDICKQFSPAEVASLMSISDKLASLNVARFAEWTMEHNEQNAKAALFAFKGDVYTGLEAETLTNAEIDYAQRHLRMLSGLYGLLKPLDLMQPYRLEMGTKLANPKGKDLYHFWDNIITQHLQQAIDAQEDNILVNLASDEYFGAVQAERLTAKIVKPVFLDEKNGKYKVISFYAKKARGMMVRFMLQTQPTSIEQLKAFNYGGYWFDETASTDTELVFKREEQ
What are the official names of this protein?
UPF0246 protein HAPS_0280.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CHO2_LACBS
Sequence: MTSSQSFLRQRKPQANDETESELHNTPEPTKQDVVWGKTPGGEVFRVPTTHDVITTLFNPRYKKSHLDLLNLTLLGFQLVLFFILPRRASQIFFLFYFAFWRGAYDAGLGWVLTKQSKKKWIVREVQRLGWLDEKRRPAVRNWIRKQLADKMGKDYSFDDLPLEYNTWLLFRQAVDVILVNDFLSYCMFAFSCFRVPEGLSVLALLILRRWLGGFLLIAFNLWVKTEAHNVVKDYGWYWGDVFFQRGNLVFDGVFELAPHPMYSVGYAGYYGLSLIAGSYAVLFVSLAAHAAQFAFLVFFENPPVAASYKKISRHVSQPSNASSNGDIEMDPNTRSLISSPRKSATSQHDLLNKYFRRDVVVLRNLDLLRSTDAMLVLIIAYALMISFLPTLSARTMLALHFLHALAWCMIHYVGLGLILQAQSKTKFLVRHFMKNYHYSQNDGGGGAIVEAFTNWKAIYNLSMCMTYVSCVGVVWKSYSLPHDWTVGNELLRHTLGALLVGLHVWASMESFEVLGVFGWFFGDFFMEEFPTHLEYTGIYRYLNNPEAMGGAAWFGLALISGSKLVLSLAVIRHLANWWFLSSVENPHMRKLYGDSLRKDAGFVKVIKNHAPELKRVAREVKGTFDKVFEETADAVEDFLAKCERSSGPRISEVVQETKVLLQQSRERLVITRVSNDISAYDSSKYHVSISPSSLTGERTFHLGEPITIKWQAPHKHSRKDWIGLYRVGANKSNTVTKTSSMGMWLPVHGEEWDGDVPLGLKRVPSKHLESENGVVTFKGNTLPWLVGHYEVRYHHDGKYNVMSMDGPLEIFVDKPSDMTFSSVRNSLMRIVPLCLDSDPSLIPFSCKDRDPDDFSFWSEHQAKRICAAIKQVFNVDYAPEVVVADANLTALANRILISKEILSTRSDT
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RPOC_ANADF
Sequence: MKDIFNFFEKPKDPLSFSAIRISLASPDKIRQWSHGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYKRMKHRGVVCEKCGVEVIQSKVRRERLGHITLATPVAHIWFLKSLPSRIGNLLDITLKDLEKVLYCESYIVIDPKETTLQRGELLSEDRYHKSMEEFGEEAFLAGMGGEAVLELLKVVGPADKGHGEGVHGLADELRAQMKEATSDAKRKKIAKRLKVVEAFVQSGNKPDWMMLEVIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPDIIIRNEKRMLQEAVDALFDNGRRGKTITGPNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKIMALELFKPFIYNKLEEKGYVTTIKSAKKMVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQMEARVLMMSTNNILSPAHGKPIIVPSQDIVLGIYYMTRERAFARGEGKVFASEEEVRAAYDQGEVDLQAKIWVRLDGKRVETTVGRVLLYDIVPKRLPFESINKVMDKKQLQNLIDLTYRLCGEKETVLLADRVRSMGYGNATRAGISIALENMIIPRKKQELLERAMGEVDDIQTQYTEGLITIGERYNKVIDIWAQVTEEVAQEMMSQIGQETAIGTGKDGKREERKQPSFNPIYIMADSGARGSAQQIRQLAGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDAIITEYDCGAMDGITLGALVEGGEIIEPMGERILGRVALDDIHDPFASSVLVKANEEIDESKVKLIENAGIDKVKIRSVLTCQARRGICVECYGRDLARGRKVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRRAEQSTIENRNPGLVKFHNVAVAKKKDGTLIVMNRNGEIIVTDDQGRERERYGVVYGAKLLVRDGQKIETSTLLAEWDPYSMPIITEVAGHVKYGDLVDGVTISEQVDEITGLARKAVIASKDPDARPRISIKDDQGKTRKLANSEADARYMLPEGANLVVNDGDEVDAGDVIAKMPRETTKTKDITGGLPRVAELFEARKPKEHAVISEIDGVVAFGKDTKGKRKVVITPEVDGKLRPDLAKEYLIGKGKHISVHTGDRVRAGEALMDGAANPHDILRVLGEKELARWLVDEVQEVYRLQGVKINDKHIETIVRQMLRRVRIVDVGDTNFLADEQVEKFVFEEENDKVITAGGRPAQGEPLLLGITKASLSTESFISASSFQETTKVLTEAAISGKVDHLRGLKENVIMGRLIPAGTGLPHYKHLDIEVETPVDAVEEAEEALAVASGEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HUTU_SALPC
Sequence: MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPSGWRWEEYQKNAQSDPHGTMQAAKRSMAAHVRAMLAFSKMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_STRA3
Sequence: MTRYKAQISYDGSAFSGFQRQPNCRTVQEEIERTLKRLNSGNDVIIHGAGRTDAGVHAYGQVIHFDLPQARDVEKLRFGLDTQCPDDIDIVKVEQVSDDFHCRYDKHIKTYEFLVDIGRPKNPMMRNYATHYPYPVIIELMQEAIKDLVGTHDFTGFTASGTSVENKVRTIFDAKIQFEASKNLLIFTFTGNGFLYKQVRNMVGTLLKIGNGRMPISQIKTILQAKNRDLAGPTAAGNGLYLKEIIYEDKECFSNFRK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: THIP_SALTY
Sequence: MATRRQPLIPGWLIPGLCAAALMITVSLAAFLALWLNAPSGAWSTIWRDSYLWHVVRFSFWQAFLSAVLSVVPAVFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLWQMLGLQWTFSPYGLQGILLAHVFFNLPMASRLLLQSLESIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLGGGPQATTIELAIFQALSYDYDPARAAMLALIQMVCCLALVLLSQRLSKAIAPGMTLTQGWRDPDDRLHSRLTDALLIVLALLLLLPPLVAVVVDGVNRSLPEVLAQPILWQAVWTSLRIALAAGVLCVVLTMMLLWSSRELRQRQQLFAGQTLELSGMLILAMPGIVLATGFFLLLNNSVGLPESADGIVIFTNALMAIPYALKVLENPMRDITARYGMLCQSLGIEGWSRLKIVELRALKRPLAQALAFACVLSIGDFGVVALFGNDNFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFTLFTLIEKLPGRHAKTD
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import (PubMed:9535878).  Probably responsible for the translocation of the substrate across the membrane (Probable).  Is also involved in thiamine pyrophosphate transport (PubMed:9535878).
What are the official names of this protein?
Thiamine transport system permease protein ThiP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: P2C28_ORYSJ
Sequence: MLAAVMDYFRSCWGPRSPAGHRVRGSDVAGRQDGLLWYKDAGQLVTGEFSMAVVQANNLLEDQSQVESGALSMAEPGPQGTFIGVYDGHGGPETARFINDHMFHHLRRFATEHKCMSTDVIRKAFQATEEGFLSLVSKQWSLKPQIAAVGSCCLVGVICSGTLYVANLGDSRAVLGRFVKSTGEVVATQLSSEHNACYEEVRQELQASHPDDPQIVVLKHNVWRVKGLIQISRSIGDVYLKRPEYNREPLHSKFRLRETFKRPILSSEPAIAVHQIQPNDHFVIFASDGLWEHLSNQEAVDLVQNNPRNGIARRLVKVAMQEAAKKREMRYSDLKKIDRGVRRHFHDDITVIVVFLDSNAISKANWSRGPSVSLRGGGVTLPANSLAPFSTPTVLSSTY
What are the official names of this protein?
Probable protein phosphatase 2C 28, OsPP2C28.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RL22_LISMO
Sequence: MASEVTSAKAVAKTVRIAPRKARIVIDLIRGKQVGEAIAILKYTPRSASPIIEKVLKSAIANAEHNYDLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSEVKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YBEY_SALDC
Sequence: MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIRLVDETESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_STACT
Sequence: MSRLFEGVGVALTTPFTNNEIDYEALEKHVDYLLNNNIQSIVVNGTTAENPTLSDEEKDEVLKAVVKQVDGRVPVIAGTGTNATKKSLEASLRAKEIGADAIMLITPYYNKTSQRGLVAHFTTIADAVGLPVVLYNVPSRTNMTIDVDTMVELAKNPFIVAIKDATNDFDYHNKLKERLDLSDFSLYSGNDDNVVRYFAEGGNGVISVVANAIPGDFQALYEKSKRGEAIDKDFEPISRLLNALSVDVNPIPIKALTAVEGFGNYEVRLPLVTLESSDRKQLEEAYAKYKAGEL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PARPJ
Sequence: MELNNLKPAEGSKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLSDLEKLPVDEIDLLALKQAGLIGEMITSAKIIKTGELKRKVVVKGLGATKGARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: BVGA_BORPE
Sequence: MYNKVLIIDDHPVLRFAVRVLMEKEGFEVIGETDNGIDGLKIAREKIPNLVVLDIGIPKLDGLEVIARLQSLGLPLRVLVLTGQPPSLFARRCLNSGAAGFVCKHENLHEVINAAKAVMAGYTYFPSTTLSEMRMGDNAKSDSTLISVLSNRELTVLQLLAQGMSNKDIADSMFLSNKTVSTYKTRLLQKLNATSLVELIDLAKRNNLA
What is the function of this protein?
Member of the two-component regulatory system BvgS/BvgA.  Activates the transcription of virulence genes.
What are the official names of this protein?
Virulence factors putative positive transcription regulator BvgA.
Protein: RECQ_BACSU
Sequence: MLHRAQSLLAHYFGYEKFRSGQDEAIRLVTEARQNTACIMPTGGGKSICYQIPALMFEGTTIVISPLISLMKDQVDALEEAGINAAYINSTQSNQEIYERLNGLKEGAYKLFYITPERLTSIEFIRILQGIDVPLVAIDEAHCISQWGHDFRPSYRNIEILFRELHDKPVIMALTATATPEVHDDICKQLHIQKENTVYTGFSRENLTFKVVKGENKDRFIDEYVQNNRHEAGIVYTATRKEADRIYERLKRNQVRAGRYHGGLADDVRKEQQERFLNDELQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGRAGRDGLASECVLLFSPQDIMVQRFLIEQSEHEEKQKQDLKKLRQMVDYCHTEDCLQRFILMYFGEKEPDACGQCGNCTDTRAAHDVTREAQMVLSCIIRMKERFGKTMVAQVLAGSKNKKVLENGFSDLSTYGILKHQSVGEISDFIEFLISDDFIRMSDGTFPTLFVSSKGRNVLKGELSVARKEALKAAAITENDELFERLRMVRKEIAAEQGVPPFVVFSDQTLKEMSGKQPVNDDELLSIKGVGEQKRAKYGRLFLQEIQAYARMTD
What is the function of this protein?
Probable DNA helicase.  Required for DNA repair and intramolecular recombination; probably has overlapping function with RecS (AC P50729).  It probably acts to help generate ss-DNA from ds-DNA breaks.
What are the official names of this protein?
Probable ATP-dependent DNA helicase RecQ.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Localized throughout the nucleoid in the presence or absence of DNA double-strand breaks.
Protein: HIS8_ACIB5
Sequence: MTVSTAQMRFWSPEVRELEPYVPGEQPKIQNLLKLNTNENPYPPSPKVVEAVQAVLHEQADALRLYPDPDATALKQAIAKQQNIDVSQVFVGNGSDEVLAHIFKAFFLQDEPILYPDITYSFYPVYSQFFGTKTKEIPLNESFEIDVRDYTQPNGGVIITNPNAPTSIALSLAEIEQVLQANPDRVVVIDEAYVDFGAESAVSLINRYENLVVCQTTSKSRSLAGLRVGFAIAQSHLIAALEAVKNSFNSYPIDRFAIAAAVASFEDQAYFEEQCQKVITSREKLVRDLTELGFNVLPSKANFIFATHSQHDAGQLAQKLREQGIIVRYFNKPRINQFLRITVGTDEQNARLVQTLKQDIL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: Y2141_ARCFU
Sequence: MPDGCDNQRGREGCENRPKQMQGVLRVREGMSVRGANRYGLSFEGIIQLLGGDDEARKAVALLRKHFRRGKIPKDELDVETALTLDYFRLALPVSSFHDSLSWKMRFFAIEDMEVPYIVRFFIEDVERGIGDWKATVERYFRAIGEERAEDFVKIFEEMVERSKNLIICGEDIVDISMKYGRDGGVVIAEMKGAGLISPTVGCGAFGRAKAPLYEINRFFAMLLEKQG
What are the official names of this protein?
Uncharacterized protein AF_2141.
Protein: HCHA_PSEA8
Sequence: MSNERDTSRTPTPDHAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYKGGKKVLMIGTDERYILMQNGSMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSIYAKYLPKLKAPQKLADLLEQAVADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKDRYIITLCHGPACLLAPAVEEKPEDYPFKDYEICVFPDALDTGANLEIGYMPGPLPWLVGENLQKLGVKILNKGITGQVHRDRKLLTGDSPLASNNLGKLAAKTLLEAFAR
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACC_ENTFA
Sequence: MIVTVTMNPSIDISYLLDHLKLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGVLGGFHGAFIANELKKANIPQAFTSIKEETRDSIAILHEGNQTEILEAGPTVSPEEISNFLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQGPWKPYLIKPNLEELEGLLGQDFSENPLAAVQTALTKPMFAGIEWIVISLGKDGAIAKHHDQFYRVKIPTIQAKNPVGSGDATIAGLAYGLAKDAPAAELLKWGMAAGMANAQERMTGHVDVENVKKHLMNIQVVEIAK
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: MCFB_DICDI
Sequence: MSNNNNNNNNNNNNNNNNNNNNNNNNNNDKNNNNNIDSSIKEKKLKEWFDKFDVDKDGSLDSNELKKGFKLHANIDMKDEQITKMMERADSNKNHRIEWDEFLKVASDSSSPEIEDIAEHWLQYSTKPIVHAPADVPSWKLLLSGGVAGAVSRTCTSPLERLKILNQVGHMNLEQNAPKYKGRGIIQSLKTMYTTEGFIGFFKGNGTNVIRIAPYSAIQFLSYEKYKNFLLNNNDQTHLTTYENLFVGGAAGVTSLLCTYPLDLIRSRLTVQVFGNKYNGIADTCKMIIREEGVAGLYKGLFASALGVAPYVAINFTTYENLKKTFIPKDTTPTVVQSLTFGAISGATAQTLTYPIDLIRRRLQVQGIGGKDILYNGTFDAFRKIIRDEGVLGLYNGMIPCYLKVIPAISISFCVYEVMKKILKIDSKKISYQS
What is the function of this protein?
Calcium-dependent mitochondrial solute carrier.  Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial substrate carrier family protein B.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.