PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_LACP7
Sequence: MHTKRIIPCLDVHNGRVVKGTNFLNLRDAGDPVLVGAEYGQAGADELVFLDITASSDARTIKLDMVRKVAETVFIPFTVGGGIRSIEDFKLILREGADKIAVNTAAIMNPTLISEAADKFGSQCVVVAIDAKCRPDNSGWNIYKNGGRIDMGIDAVEWAMKANELGAGEILLTSMDCDGTKNGYDLELTKQISENVSIPVIASGGAGTKEHFYEALTRGKADAVLAASLFHYKELEINDLKEYLRMKEVSVRLEDRSC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT2_STAAW
Sequence: MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase 2, OAT 2, Ornithine--oxo-acid aminotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_MANSM
Sequence: MNYMQDNDKLYRYLFQDRAVRGEWVRLNQTFIDTLNTHHYPNVVRNLLGEMMVATNLLTATLKFNGDITVQIQGDGPLRLALVNGNHRQQIRALARIDGEIRDDMSLHQLIGKGVLVITIAPQEGERYQGIIALDKPTVTECLEEYFQRSEQLQTQLLIRVGEYEGKPVAAGMLLQIMPDGSGSPDDFDHLATLTATVKDEEIFGLPAEELLYRLYHEETVELYEPQAIQFHCGCSQERSGSALLLINDDEIDEILEEHNGSIDMQCECCGTHYFFNKEAIEKLKKSGEEPVTTH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_SHEHH
Sequence: MAQFFKAKPNTSKQLSSKLSLKVTQLDHLGAGIAHHDGKIVFINGALPGETVSVQLTEQKKKFARAKLLKIDKASAQRVSPLCPHFDKCGGCDLQHLDIDAQRKHKASTLVDLVNKFAQTQAGEVCDTLSDNAWHYRRRARLATWFDKNTKHISLGFRASSSSDVVEIQSCAVLAEPLSALIPDLAFMLNQLSGKKALGHVELTQADNGNFVVLRVTKALSDKDKARLVEFANKHQVIVLLQDDDAQCEHLNGAGEQPYYGFDDNQVKLNFSPGNFIQVNAQVNQAMVSQAVEWLSPKADERVLDLFCGIGNFSLPLAKDGAEVIGVEGVQAMVEQARINAKQSGLDKVSFYHADLSADLSKEPWLGKVDKMLIDPARAGAYESMQSLKKLKPKALVYVSCNPASLARDSEVILKQGYQLKKIGLVDMFPQTHHLESMALFELKN
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: ARHG8_HUMAN
Sequence: MEPELAAQKQPRPRRRSRRASGLSTEGATGPSADTSGSELDGRCSLRRGSSFTFLTPGPNWDFTLKRKRREKDDDVVSLSSLDLKEPSNKRVRPLARVTSLANLISPVRNGAVRRFGQTIQSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKLYIFLFQDILVLTRPVTRNERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHTLQANDVFHKQQWFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQVEVDENAYRCGSGMQMAEDSKSLKTHQTQPGIRRARDKALSGGKRKETLV
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.  May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
What are the official names of this protein?
Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CSGA_ECOLI
Sequence: MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSATLDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY
What is the function of this protein?
Curlin is the structural subunit of the curli fimbriae.  Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius.  Curli can bind to fibronectin.
What are the official names of this protein?
Major curlin subunit.
What is the protein family that this protein belongs to?
Belongs to the CsgA/CsgB family.
What are the subcellular locations of this protein?
Fimbrium. Note=Part of the curli surface structure.
Protein: YIDC1_STRA3
Sequence: MKKKLKTFSLILLTGSLLVACGRGEVSSHSATLWEQIVYAFAKSIQWLSFNHSIGLGIILFTLIIRAIMMPLYNMQMKSSQKMQEIQPRLKELQKKYPGKDPDSRLKLNDEMQSMYKAEGVNPYASVLPLLIQLPVLWALFQALTRVSFLKVGTFLSLELSQPDPYYILPVLAALFTFLSTWLTNKAAVEKNIALTLMTYVMPFIILVTSFNFASGVVLYWTVSNAFQVFQILLLNNPYKIIKVREEAVRVAHEKEQRVKRAKRKASKKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUS1_ACIFR
Sequence: GALDGSWKEATLPQVKAMLQKDTGKASGDTVTYSGKTVHVVAAAVLPGFPFPSFEVHDKKNPTLDIPAGATVDVTFINTNKGFGHSFDITKKGPPFAVMPNIKPIVAGTGFSPVPKDGKFGYSEFTWHPTAGTYYYVCQIPGHAATGMFGKIIVK
What is the function of this protein?
Electron carrier from cytochrome c552 to the A-type oxidase.
What are the official names of this protein?
Rusticyanin.
What are the subcellular locations of this protein?
Periplasm.
Protein: RIBA_HAES1
Sequence: MSKIQLVAEAKLPTEFGIFRIVGFEFPDTQKEHVALVMGDINDDKPVLARIHSECLTGDALHSLKCDCGFQLATALRQISEAGRGVLIYHREEGRGIGLINKIRAYALQDQGLDTIEANLALGFAADERNFSVCADIFALLGVKQVRLLTNNPNKIETMKKSGINIVERVPLNVGENRYNTEYLDTKAKKMGHFIVHNNEQHLIACPHCQEEIPKK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: UNG_SALHS
Sequence: MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS1_GLIGL
Sequence: MGLEKSLVFFPLLVLLALGWVQPCLGRESSAHKFRRQHMDSEGLSSSSSSPTYCNQMMQRRKLTRGHCKPVNTFVHEPLADVQAVCFQENVTCKNGQTNCYRSGSSMHVTDCRTTGSSKYPNCAYRTTQKVKRIVVACEGDPSVPVHYDGSVEDST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSB_ECO5E
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPVHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYSG_SHISS
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDTLNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMSERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: YIHY_ECOSM
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLV_PSYIN
Sequence: MTTIVSVRRGNQVVVGGDGQVSLGNTVMKGNARKVHRLYNNQVIAGFAGGTADAFTLLERFEAKLQAHQGNLERAAVELAKDWRTDRSLRRLEALLAVADKNSSYIITGNGDVVRPENDLMAIGSGGYFAQSAAIALLENTDLDAKTIVEKALAIAGNICVFTNETHTIECIDFSDEITTESKK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US22_HCMVM
Sequence: MSLLTKAAAEAWGTYLRQRDERCEDAIRCDYGVFQFRNTVFQKTLSMLQGLYLRQYDPPALRTYVQRHQGTTVALRNPANWFLVMREQAAIPQIYARSLAADYLCCDDTLEAVGVLAVRPPDSDLTRNTKQAQELPCVLMLSHYGTVYVYDWETDGLYEVASDIKAFSKNGLLWCEYVYRHPQTPFATTEPRYHVQKFLCTDPTDAAAVAKTAREMNGLNLVIRTPGRTEVEPLLMLGSIEGLRACRPFDHMPAADFRDLLNFIRQRLCCEWYVVGLVGYYLAYGPFVPSGMVLLDKFGVVYLHKIEDSDLYRIADNFHMFLKCGLLKLRGLCRFDRGLRGECRLEELPVCHHTLKRDVLRWHGALGTITRSQLESALDWFLRPTRGTDKVPNNSSAWGRTDLLPTGALQDNQNWAFPSHSVETLPALQGGLWEDNDETTQTVDGQRCFRMPKFFPPPMCRAPYNECGVELPGGDSSDEDESGRPRRIANRIGDTPETPCNSENEDDTTVEGTSGGPEAMDSQAPYPSEDSPTTEKEAWLQRGRRAKAMHARGHTLKQVPIPEPDQMGDDGPDPGP
What are the official names of this protein?
Tegument protein US22.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: RL2_ASTYP
Sequence: MAIKKYKPTTNGCRNMSVSAFSEITTQTPEKRLLVSHKDQAGRNNQGKITVRHRGGGVKRKYRLIDFKRNKDNIVGKVATIEYDPNRSANIALIHYLDGEKRYILAPKGLTVGMQIVSGKEADIKVANCLSLMNIPVGTTVHNIELKPGKGGQIARSAGSFCQIISREDKYVLLRLQSGEVPKVLGTCRATIGEIGNESYKLINYGKAGKKRFLGIRPTVRGSAMNPNDHPHGGGEGRAPIGRKSPMTPWGKKARGVKTRDRKKASNALIIRRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TLP40_SPIOL
Sequence: MSSFINHHFYPSVCTSKHALPINPTSPFYLGIPNFRQKSRFMHLTPRCFSRQIDPLDKQKKRSFSVKECAISLALAAALISGVPSLSWERHAEALTSPVLPDLAVLISGPPIKDPEALLRYALPIDNKAIREVQKPLEDITESLRVLGLKALDSVERNLKQASRALKNGKSLIIAGLAESKKDRGVELLDKLEAGMGELQQIVENRNREGVAPKQRELLQYVGSVEEDMVDGFPYEVPEEYQTMPLLKGRAVVEMKVKVKDNPNVDNCVFRIVLDGYNAPVTAGNFLDLVERHFYDGMEIQRRDGFVVQTGDPEGPAEGFIDPSTEKPRTIPLEIMVEGEKVPVYGSTLEELGLYKAQTKLPFNAFGTMAMAREEFENNSGSSQIFWLLKESELTPSNANILDGRYAVFGYVTDNQDYLADLKVGDVIESVQAVSGVDNLVNPTYKIAG
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Has a regulatory effect on thylakoid protein phosphorylation.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, chloroplastic, 40 kDa thylakoid lumen PPIase, 40 kDa thylakoid lumen rotamase.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen. Note=Can interact with the inner surface of the stroma-exposed thylakoid regions.
Protein: RL34_LISMH
Sequence: MKRTYQPSKRKRKKVHGFRTRMSTKNGRRVLASRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARO1_CANDC
Sequence: MSIERVPILGKETIHVGYGIADHIVNEVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSKKRPESRLLTYCVSPGENNKNRVTKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKNDGSKIRCVLLEKIGKCYQLKAHQVSKQDLSFVLTDEVLVHPFTNPPKENIIVPPGSKSISNRALILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGNLVTCGEELYLGNAGTASRFLTTVASLVGKSPASDDVILTGNARMQERPIGPLVDALRSNGSEIEYLNKQGSLPLKISAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEEYTYHIPKGIYKNPTEYVIESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDARFAVDVLKPMGCKVEQTATSTTVTGPPRGHLKPLPHVDMEPMTDAFLTASVVAAVAKGGSTSITGIANQRVKECNRIEAMVTELAKFGVSANELPDGIEIHGIDIKDLKTPEISDRGVCSYDDHRVAMSFSLLAGLCKEPVLILERSTTGKTWPGWWDILHSKFKIELDGYEPPFNTDKHVIKSSDKGVIVIGMRGTGKSTLSEWLASFLGFKMLDMDKYLEEKLGTDIKSLIKAKGWEHFRKEEAIVAKECFTKFSKGYVLSTGGGIVEGEDARQQLKSYADNGGIVLHLHRDLDETVTFLAADTTRPAYSSEVQEVWLRREKWYHECSNYHFYSSHCSTEDEFNHLRKSFVNYIKLITGAERSVVPTGRSTAVVLTLPDLNNVAGDLESITIGADAVELRVDLLKDTSAAFVAAQIATTRKHADLPIIYTVRTVSQGGKFPDENVDELKSLLLLGIRLGVAYIDLQLTAPNELIEEISSKKGFTRIIGTYQDINGELKWNNVEWKNKYNQGVSMNADIVRLVGRANSIQDNLDLEDFKKQNTLKPLIAFNLGTQGKLSQVLNGTFTPISHQLLPNDDGLLTIGEINQTYFDIGGFTAKKFWVIGSPIEHSRSPNLHNAGYKALNLPYQFGRFEATDVDVVYDNLINKSDFGGLAITMPLKLDIMKFATKLSDAAETIGAVNTLIPVEGGYFGDNTDWVGISNSFIRAGVPPKSSSNGLVVGAGGTSRAAIYALHQMGCTKIYLVNRTVAKLEELVKSFPKDYNLEIVETEQQADKVNKVLLAVSCIPADKPLDSDVLKKIERILSNGSEQVAGFKPTLLEASYKPRVTPIMKLAEEQYKWKVIPGVEMLVNQGDRQFKLHTGFSAPYEIIHRAVVEE
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_RHIWR
Sequence: MTEAKAAWNALRDTPATSLTELFTNEPDRLSRLSMEEAGILFDFSKTHLSAALIDRFAALAEASGFAARRDALFAGAAVNVTEDRAAEHPAERGQGAPDSVARARGFHARMRGMIDAIEAEVFGPIRHILHVGIGGSALGPDLLVDALGRDAGRYEVAVVSNVDGAALDAVFRRFDPQATLLVVASKTFTTTETMLNARSVLAWMEEDNVEDPYSRVIALTAAPEKAVEWGIDETRILPFSESVGGRYSLWSSIGFPVALALGWDAFEELLEGAAAMDRHFRLAPPSANIPLLAAFVDQYYSVLRGAETRAVFAYDERLRLLPSYLQQLEMESNGKGVKADGSPVDGPTAAITWGGVGTDAQHAVFQLLHQGTRLVPVEFVAAIEPDHVLDDAHHRTLLVNCFAQGAALMAGRDNGDPARAYPGDRPSTTILLDRLDPGRLGALIAFYEHRTFANAVLLGINPFDQFGVELGKEIARSIESEGTDRFDPSTRALIARALG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_SHEHH
Sequence: MIQMQSTLEVACNSGARRVQCIKVLGGSHRRYAGIGDVIKVSVKEAIPRGKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YHBP_ECO45
Sequence: METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAIAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: MURG_STRU0
Sequence: MTKRILFTGGGTVGHVTLNLILIPKFLKDGWEVHYIGDKKGIEYQEIQKSGYPVTFHAIKTGKLRRYFSWQNLIDVFKVATGLLQSLVIINKVKPQALFSKGGFVSVPPVIASRLMGVPVFVHESDLSMGLANKIALKFASTMYTTFESQVTNPIIKHIGAVTKVSKESGNYLPELSDIQNKFNPQLKTLLFIGGSAGAKVFNQLITNNPDLTKAFNVINITGDSQLNELSQNLYRVDYVTDLYQPLMQLADLVITRGGSNTLFELLAMQKLHLIVPLGKEASRGDQLENANYFEKQGYARQLSEELFNPETLISEVHYLLEHQDQFRKAMSESQEIKSPDVFYDLLKNDISLKAKGK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RBFA_BRUA1
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRSPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHG_BACSU
Sequence: MYPDLKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKAGGEAVVVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKQKADVESMIPMGYIGEPEEIAAVAAWLASKEASYVTGITLFADGGMTQYPSFQAGRG
What are the official names of this protein?
Glucose 1-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: VE6_HPV57
Sequence: MSEENPCPRNIFLLCREYGLELEDLRILCVYCKRPLSDADVLAFAVKELFVVWRKGFPYGACEKCLIAAAKLRQYRHWHYSCYGDTVETETGIPIPQLFMRCYICHKPLCWEEKEALLVGNKRFHKISGQWTGHCMNCAPRCMENAPALRTSH
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: COBT_CLOD6
Sequence: MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICMQLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVISKFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAEQCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIRKAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYKINPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYTYKNMATFDEIDMGR
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RBL_GALPA
Sequence: MSPQTETKAGVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASRGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAAEGGEIIREACKWSP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.