PharMolix/UniProtQA huggingface dataset:
Protein: KAD_CLOTE
Sequence: MNIILLGPPGAGKGTQAKLISEKYSIPHISTGDIFRKNISNKTPLGMEAKSYMDKGQLVPDELTIEIVKDRLGEEDCKNGFLLDGFPRTVKQAEALDEFLQNKSSKTDAALLIDVPQELILERMTGRRVCGECGASYHIKFITPKTEGVCDLCGGKLVQRKDDTKETVLERLEVYSKQTQPLIEYYKNKNVLLALDGTKEKNEVFENISNVLGAIN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFC_BUCAI
Sequence: MPLPDKFFLFIQDDYHNVKLRVKINEKVLRGQPLIFSDDFNVPVHAPTSGLIENICFNSDSIKKNIKIVISPDYLDQWIRLNPIKDYKKYAPEKLIKIIHQSGVVGLGGGQFPSSKKIIFSINRAHTLIVNAVESEPYITSDNCLIYNHISEILIGCKIICWITKIKTVLIAIQEDNIQSISKIQHLIKNKSLFKICIIKKKYPAGSSKVLVKSLTGKEVPHGKHSIDIGYLIFNVATIFSIKRAIINGKPLTERVVTLMSDKNLLSGNFWVRIGTPIKYFLTSNKLKQSFIASVYLGGPFMGKKINNLNHSILKKTNSIFITHKKEKNESISEKTCIRCGYCSYVCPVNLLPQQLYWYIKNKNHVQTKKHYVLDCIECKACEKVCPSYIPLVKYFIQEKNILKNITLENNRKKMSLIRFKTREQRLFNEKRMIHENNDTFLMKKKDKKINNITKTVLKKTLQDAIERMKSKQ
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IOLD_HALH5
Sequence: METIRLTTAQALIKFLNQQYVHSDGEEFPFVEGIFNIFGHGNVLGIGHALEQDPGHLKVYQGKNEQGMAHTAIAYSKQMLRKKIYAITTSSGPGSANLVTAAATALANQIPILLLPADTYATRQPDPVLQQFEQEQSIAITTNDALQPVSRYWDRITRPEQLMSSLIRAFEVMTDPAKAGPATICISQDVEGEAFDYDVRFFEKRVHYIDRKLPSERELKGAADLIKKSKRPLLVVGGGAKYSEAREALIAFSETFNVPLTETQAGKSAVEASFKNNLGGLGITGTLAANKAAQQADLVIGIGTRFTDFATSSKTLFDFEKVKFVNINVSRMQAYKLDAFPVVADAKRTLEALVPMLEGYKSEYGDDIGQLKAEWLKERERLGKVTFDRERFEPEIKGHFTQEVMNEYADALQTEFAQTTALLTINETIDPDSVIICAAGSLPGDLQRLWHAEVPNTYHLEYGYSCMGYEVSGTLGLKLAEPNKEVYAIVGDGSFLMLHSELVTAIQYHKKINVLLFDNSGYGCINNLQMDFGGGSYFCEFRTADEKILHVDYAKVAEGYGAKSYRVSTVEELKAALEDAKKQECSTLIDIKVLPKTMTDGYDGSWWNLGVSEVSDREGIQKAYELKQEKLTRAKQY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: ODPX_YEAST
Sequence: MLSAISKVSTLKSCTRYLTKCNYHASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEVETDKSQIDVEALDDGKLAKILKDEGSKDVDVGEPIAYIADVDDDLATIKLPQEANTANAKSIEIKKPSADSTEATQQHLKKATVTPIKTVDGSQANLEQTLLPSVSLLLAENNISKQKALKEIAPSGSNGRLLKGDVLAYLGKIPQDSVNKVTEFIKKNERLDLSNIKPIQLKPKIAEQAQTKAADKPKITPVEFEEQLVFHAPASIPFDKLSESLNSFMKEAYQFSHGTPLMDTNSKYFDPIFEDLVTLSPREPRFKFSYDLMQIPKANNMQDTYGQEDIFDLLTGSDATASSVRPVEKNLPEKNEYILALNVSVNNKKFNDAEAKAKRFLDYVRELESF
What is the function of this protein?
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes.  This specific binding is essential for a functional PDH complex.
What are the official names of this protein?
Pyruvate dehydrogenase complex protein X component, mitochondrial, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, Pyruvate dehydrogenase complex component E3BP.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS15_SALPK
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SC23C_ARATH
Sequence: MAEFGELEAQDGVRMPWNIIPVATKKEQSIDSEVPVSAIYTPLKPLRSQSLLLPYSPLRCRTCRSVLNPYSVVDFSACNWGCPFCFNRNPFPLNYSSVADNNLPPELFPHSTTVEYLCDSFSSPSPPVFLFVVDTCLISEELDFLKSSLFQALDLLPDTSILGLITFDSLVRVYELGFPHCTKSYFFHGNKDCTKDQLLDQLSFFVKNPKPSSGVIAGARDGLSSDDIARFLLPASDCHFTLHSVLEELGNSPWPVAADHRPARCTGVALRIAASLLGACFPGSAARIMAFIGGPSTQGPGAIVSRELSDPIRSHKDIDKDSAMYYHKAVEFYEMLAKQLVHQGHVLDVFASSVDQVGIAELKVAVEQTGGFVVLAESFGHSVFRDSLKRVCQSGENDLGLSSCGIFEINCSKDIKVQGIIGPCASLEKKGPLCSDTAIGQGHTSAWKMCGLDNNTSICLVFEIAKIDTADVVLQSQSNQFYFQFLTYYQHSNGQTRLRVTTLSRRWVMGTESLQELSNGFDQEAAAVVMARLISSKMETQPEFNPQRWVDKALINLCTWFGDYQKGNPSSFSLSSQLSIFPQFVFHLRRSQFVQVFNNSPDETAYFRMILYRENVSNSVVMIQPSLISFSFHSPPEPILLDVASIAADRILLLDSYFTLVIFHGSTIAQWRKAGYHNQPEHQAFGHLLQSPRDYADTIMSERFPTPRLVICDQYGSQARFLLAKLNPCDGDAHFSGQSNVFTDDVSLSVFLDHLRRLIVH
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23 C, AtSEC23C, Protein transport protein SEC23 D, AtSEC23D.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
Protein: TCF23_MOUSE
Sequence: MSQEATEAPAMPGEGHGHNKAKARWLLGTDRKRSRINRTRQDLWEDTSWSNHRLSRATSAPRGTRARGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHELPGPAWPPFVRGLRYLHPLKKWPMRSRLYAGGLGCSDLDSTTAITTGQRCKDAELGSQDSVAAESLLTSPAFGNK
What is the function of this protein?
Inhibits E-box-mediated binding and transactivation of bHLH factors.  Inhibitory effect is similar to that of ID proteins.  Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers.  Lacks DNA binding activity.  May be involved in the regulation or modulation of smooth muscle contraction of the uterus during pregnancy and particularly around the time of delivery.  Seems to play a role in the inhibition of myogenesis.
What are the official names of this protein?
Transcription factor 23, TCF-23, Basic helix-loop-helix transcription factor OUT, Ovary, uterus and testis protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOAC_CHLAD
Sequence: MSGSIDQLSHLDAAGRARMVDVGNKAVTAREAIARGRVVMQPATLQLIVSGGMPKGDVLAVARVAGIMAAKRTAELIPLCHLLNLSHASVNFTPDPAGNALEIEATVRCTGQTGVEMEALTAVSIAALTIYDMCKAVDKTMQIDGIRLIAKRGGRSGDWQREESA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: NDHO_PROMS
Sequence: MTDSIPKKPLKKGSLVFVDKENYIKSIEALASDNDLPNYVFEGPGEILSLKDEYAQVRWRRPVPDVWLKLDQLKEYTH
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YO95_CAEEL
Sequence: MTKHLLLMLQILYVLRIFRTQMVIQTSPVRSIYQNLRIHHVFQIREILLLHMAHEVLHFYCCLGFSPFFYNSRFLQFKVSIRCPLFHAQNIFNSKLEKYECTFKYYSNPLLVNVIILFGLRISVWKWLYLT
What are the official names of this protein?
Uncharacterized protein T20B12.5.
Protein: OR49A_DROME
Sequence: MEKLRSYEDFIFMANMMFKTLGYDLFHTPKPWWRYLLVRGYFVLCTISNFYEASMVTTRIIEWESLAGSPSKIMRQGLHFFYMLSSQLKFITFMINRKRLLQLSHRLKELYPHKEQNQRKYEVNKYYLSCSTRNVLYVYYFVMVVMALEPLVQSCIMYLIGFGKADFTYKRIFPTRLTFDSEKPLGYVLAYVIDFTYSQFIVNVSLGTDLWMMCVSSQISMHLGYLANMLASIRPSPETEQQDCDFLASIIKRHQLMIRLQKDVNYVFGLLLASNLFTTSCLLCCMAYYTVVEGFNWEGISYMMLFASVAAQFYVVSSHGQMLIDLSTNLAKAAFESKWYEGSLRYKKEILILMAQAQRPLEISARGVIIISLDTFKILMTITYRFFAVIRQTVEK
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to butanol and 2-heptanone.
What are the official names of this protein?
Odorant receptor 49a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or49a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPAC_LACGA
Sequence: MAKELIFGHQNPDTDAIGTAIAYSYLQNKLGYDTEAVALGEANDETKYALNKFGFTAPRVIKTASNEVDAVMLVDHNEPQQSVSDIDKVKVTHVVDHHRIMNFNTADPLYYRAAPVGCTSTIMWQMYNEKEIEIPQDIAGIMLSAIISDTLLLKSPTTTDQDKEAVEALANIAGVNYKEYGLKMLKAGTNIADKSEEDLIDLDAKSFELNGSNVRVAQINVVDLPEALERKEAFLKAMDEASKSEGYDMFMLLITNILDSDSEALVVGSDESKAKFEKAFNTKLSDSEVKLPGVVSRKKQVVPPLTNAFEA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_GEOKA
Sequence: MSIRAEEISALIKQQIENYESQIQVSDVGTVIQVGDGIARAHGLDNVMSGELVEFANGVMGMALNLEENNVGIVILGPYTGIKEGDEVRRTGRIMEVPVGEALIGRVVNPLGQPVDGLGPVETTETRPIESPAPGVMDRRSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTIINQKDQNMICIYVAIGQKESTVRTVVETLRKHGALDYTIVVTASASQPAPLLFLAPYAGVAMGEYFMYKGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDIFYLHSRLLERAAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGAAQIKAMKKVAGTLRLDLAAYRELEAFAQFGSDLDKATQAKLARGARTVEVLKQDLHQPIPVEKQVLIIYALTRGFLDDIPVEDVRRFEKEFYLWLDQNGQHLLEHIRTTKDLPNEDDLNKAIEAFKKTFVVSQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: APO1A_MACFA
Sequence: MRLFLSLLVVVLSMVLKGPTPAQGVPDVSNPFDVLEEFGKTLEDNVGEFINLITQSELPAKTRDWFSETFRKVKEKLRINS
What are the official names of this protein?
Apolipoprotein C-I, acidic form, Apo-CIA, ApoC-IA, Apolipoprotein C1A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NS7_CVPPU
Sequence: MLVFLHAVFITVLILLLIGRLQLLERLLLNHSFNLKTVNDFNILYRSLAETRLLKVVLRVIFLVLLGFCCYRLLVTLM
What is the function of this protein?
May function in the formation of membrane-bound replication complexes or in the assembly of the virus.
What are the official names of this protein?
Non-structural protein 7, ns7, 9 kDa hydrophobic protein, HP, Accessory protein 7, X3 protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns7/ns7a protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: PXPA_COREF
Sequence: MNPPHSIDLNSDLGESYGSWVMGNDEAVLDLVSSANIACGFHAGDATVLLKTVVAAKARNVRIGAHIGYNDLTGFGRRAMEYDHEVLVAETIYQIGAIQAAATTVGATVDYVKPHGALYNRIAVDEAQAAAVIEAMKKLNPELPLMVLSGAPIVEQAISEGLTVIQETFADRAYTSDGRLVSRTQTGAVHHDPQVAARQALAFATGGSITSIDGDPVTVHADSICVHGDNPAALELVRTIIDTLRAHDVEVRRAR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: NRFA_SHIBS
Sequence: MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGCADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y457_BUCAP
Sequence: MLLEKIKKYLEFKINIAFIKIYDESKLHNYSTNTNTISHLKVIIVSDDFINKNLIIRHRIIFKALKEIEKESIYSITLYTYTLNEWKDKKYKEFNSIKCIQKKIKNFVLKN
What are the official names of this protein?
Uncharacterized protein BUsg_457.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: CP26B_BOVIN
Sequence: MLFEGLELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVENVFSLPVDLPFSGYRRGIQARQTLQKGLEKAIREKLQCTQGKDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAKGLLHSGGCPCEGTLRLDTLSGLHYLDCVIKEVMRLFTPVSGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFGQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSNQNKILPETEAMLSATV
What is the function of this protein?
Has also a significant activity in oxidation of tazarotenic acid and may therefore metabolize that xenobiotic in vivo.
What are the official names of this protein?
Cytochrome P450 26B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RL24_SALDC
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: METAA_STRR6
Sequence: MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLCWSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_CLONN
Sequence: MSKVTQIAHPLILHKLAIIRNKNTGSKDFRELVEEVAMLMAYEVTRDLPLEEVEIETPICKTKCKMLSGKKMAIVPILRAGLGMVDGMLKLIPAAKVGHIGMYRDEETFKPVEYFCKMPQDIHERDIIVTDPMLATGGSAIDAINALKKRGAKSIRLMCLISSPEGIKAVMDAHPDVDIYVGDIDERLNEHGYIIPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYH_THEP1
Sequence: MNYKRIKGTNDIFGEEIWYWRYVEETFRNVCESAGIEEIRTPIFEQTELFVRSVGEESDIVQKEMYTFQDKAGRSITLRPEGTAPVVRAFLENSLIDRGFQQRYYYIGPMFRYEKPQSGRLRQFHQVGFEIIGSESPKADFEVIMLVDTFLRKLGLTKYRIHLNSIGCSACRKNYREALKEYYGQILANLCDDCKRRYETNILRLLDCKVDHEYALNAPKSVDYLCDSCKTHYEKLKEYLNTFEIEYVEDHTLVRGLDYYTRTVFEVRHEGLGAQNTIAGGGRYDGLFVELGGSSVPALGFAGGIERIILALKAEEIEIPIKNVHLVYVVTLGEKAFADGVQLAVELRKKGLSVDVDIMDRKLSGQLKHAHRMGSRYAVIIGDEELEKGIVILRDLETGDQVEVDRDFAVDYIAERVSKD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKTL2_BOVIN
Sequence: MADSATLDATTVQVLQDLANRLRVHSIRATCASGSGHPTSCCSAAEIVSVLFFHTMRYRQTEPAHPDNDRFVLSKGHAAPLLYAAWVEAGSISEPDLLNLRTIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYLDKASYRVFCLLGDGESSEGSVWEALAFASHYGLDNLVAVFDVNRLGQSGVAPLKHCTDIYRNRCEAFGWNTYLVDGHDVEALCQAFSQAAQGKNKPTAIIAKTYKGRGIPNVEDAENWHGKPLPKERADEIIRLIKSQIKTNRNLLPKPPVEGSPPVSITNIKMTCLPDYKVGDKVATQKAYGLALAKLGLANERVVVLDGDPKNSTFFEIFKKEHPERFIECFAAEQNMVSVALGCATRGRTITFVTTLGAFLTRAFDQIRMGAISQSNINLIGSHCGVSVGEDGPSQMALEDLAMFRSIPNCTVFLPSDAVSTEHAVYLAANSEGMCFIRTNRSETAVIYTPQEHFEIGRAKVIRHSNNDKVTVIGAGVTLHEALAAADALSQQDISICVIDPFTIKPLDAATIISCAKATDGRVVTVEDHYQEGGIGEAVCAAVSGEPAIHVHQLSVSGVSERNRKPSELLSIFGVSARHIIAAVKYTLMN
What is the function of this protein?
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells.  Plays a pivotal role in carcinogenesis (By similarity).
What are the official names of this protein?
Transketolase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: PSBN_SYNE7
Sequence: MMEASPGLSIAITFAVILLALTGFSIYTSFGPPSKQLEDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CTCP_KITAU
Sequence: MTDTTADQTRHGDRPYDVVIIGSGLSGTMLGSILAKHGFRIMLLDGAHHPRFAVGESTIGQTLVVLRLISDRYGVPEIANLASFQDVLANVSSSHGQKSNFGFMFHRDGEEPDPNETSQFRIPSIVGNAAHFFRQDTDSYMFHAAVRYGCDARQYYRVENIEFDDGGVTVSGADGSTVRARYLVDASGFRSPLARQLGLREEPSRLKHHARSIFTHMVGVDAIDDHVDTPAELRPPVPWNDGTMHHIFERGWMWIIPFNNHPGATNPLCSVGIQLDERRYPARPDLTPEEEFWSHVDRFPAVQRQLKGARSVREWVRTDRMQYSSSRTVGERWCLMSHAAGFIDPLFSRGLSNTCEIINALSWRLMAALREDDFAVERFAYVEELEQGLLDWNDKLVNNSFISFSHYPLWNSVFRIWASASVIGGKRILNALTRTKETGDDSHCQALDDNPYPGLWCPLDFYKEAFDELTELCEAVDAGHTTAEEAARVLEQRVRESDWMLPALGFNDPDTHHINPTADKMIRIAEWATGHHRPEIRELLAASAEEVRAAMRVKP
What is the function of this protein?
Involved in the biosynthesis of chlorotetracycline (CTC), an important member from antibiotics tetracycline (TC) family, which inhibits protein synthesis in bacteria and is widely involved in clinical therapy, animal feeds and aquaculture.  Utilizes FADH(2) supplied by the flavin reductase CtcQ, to catalyze the chlorination of tetracycline (TC) at C7 position, leading to the production of 7-chlorotetracycline.  The enzyme forms a lysine chloramine intermediate on an internal lysine residue before transferring the chlorine to the substrate.  It is stereo-selective for the 4S (natural) isomer of tetracycline.
What are the official names of this protein?
Tetracycline 7-halogenase, FADH2-dependent halogenase.
What is the protein family that this protein belongs to?
Belongs to the flavin-dependent halogenase family. Bacterial tryptophan halogenase subfamily.
Protein: DBAE_EMENI
Sequence: MTIRIPSGEEADYTLHLPRILCLHGGGTNARIFRMQCRVLERFLRSTFRFVYAEAPFAAQPGSDVTSVYKDHGPFKAWLRCTAADPDRSAQEVVKKINLSIATAMYDDDMRGATGEWIALLGFSQGAKVAASILYAQQTIQQRLGERAATRPRFRFAVLMAGRGPLVWLLPETSSGPGSIPMGLVDAASPSMLDSEPELPTDSTEHMLRLPTLHVHGLRDPGLSLHRRLLRSYCQSDSVSLVEWEGEHRVPLKTKDVTAVVDQIYALARDTGVLDSWC
What is the function of this protein?
Esterase; part of the gene cluster that mediates the biosynthesis of the antibiotic 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives (PubMed:22510154, PubMed:23001671).  The direct non-reducing polyketide synthase dbaI product is 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA), produced by condensation of one acetyl-CoA starter unit with 4 malonyl-CoA units and one methylation step (PubMed:22510154).  The FAD-dependent monooxygenase dbaH is responsible for the synthesis of yellow pigments derived from the oxidation of DHMBA (PubMed:23001671).  The roles of dbaB, C, E and F have still to be determined (Probable).
What are the official names of this protein?
Esterase dbaE, Derivative of benzaldehyde biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: CLD4_BOVIN
Sequence: MASMGLQVMGIALAVLGWLGAILSCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVICIILAVFGVLLSVVGGKCTNCVDDESSKAKIMIVAGVVFLLAGLLVMVPVSWTANNVIRDFYNPLVASGQKREMGASLYVGWAAAGLLILGGALLCFNCPPRNDKPYSAKYSAARSAPASNYV
What is the function of this protein?
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney.  Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts.  Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-4.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=CLDN4 is required for tight junction localization in the kidney.
Protein: 6GAL_HYPRU
Sequence: MRSIVLPSLALALFSQRARADTTLTIDPTSNWGTWEGWGVSLAWWAKAFGNRDDLASVFFSRNNQAVNGQTLPGLGFNIVRYNAGACSNNSYDGSTMVVSPNIKPSRQMDGFWLDWASSDPSSSSWNWNVDANQRAMLQKAKANGANIFELFSNSPMWWMCNNHNPSGSGSSDNLQSWNYQNHAVYLADIAQHAQQSWRIQFQSVEAFNEPSSSWWTAEGTQEGCHFDVSTMATVIGYLNTELSSRGLSSFVASSDENTYDLAISTWQGFNSSTRNIVKRINVHGYQDGGGRRDTLYSLASQAGKRLWNSEYGDSDASGKSMYQNLLLDFTWLHPTAWVYWQAIDGAGWGLIVGDNDNLTLSSASTKYFVLAQLTRHIRQGMQILTTPDVNTAVAYDAGSQKLVIVTANWGSAQTITFDLTRARTAGSNGATVPRWSTQTGGGDQYRSYTDTKINNGKFSASFSSGQVQTFEVSGVVLQ
What is the function of this protein?
Hydrolyzes galactooligomers with a degree of polymerization higher than 3.  Hydrolyzes radish root arabinogalactan-protein.  Does not hydrolyze dextran, arabinan, starch, laminarin, beta-1,4- and beta-1,3-galactans, larch wood arabinogalactan or acid-insoluble polygalacturonic acid.
What are the official names of this protein?
Endo-beta-1,6-galactanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.