PharMolix/UniProtQA huggingface dataset:
Protein: TRM1_PYRNV
Sequence: MNLVLRREGAVQFYAPDPQRYGSIYSAPVFYNPAMEKNRTLSVLLLRTLGGGLTVCEPLSGTGVRGIRYAVESKAVARLVLNDISRDAAELIKKNLELNGVDGEVYNDDANVLLHRLKNVCDVVDIDPFGSPAPYIHAAFRALRDEGLLCATATDTAVLVGRYPRKCLRRYWSTVRKTPFYIELGLRNLVGFIARVAASEDFSIRPLMSYWEGHYFRTCVAVARGARDADDALQNVGYVVYRRGMRQTTQLPDESSSGPLWLGPLGDPLIMHQMAQHGVYSDFLGVLEQEYSIEAPWHYRLPEFAVEGVSPTLAEALDLLRRSGIYATATHMAKDGFKADAGYGEVKRALF
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: PLSX_CLONN
Sequence: MKIVVDGMGGDYSPHIVVKGCIEAIKEYNNIDIIITGPEKLINDELQKYEYNKEKITVLDAKDVITNNEHPVMAIRRKKESSIYKALQMMKNKEADAVISAGSTGAFLAGATLVVGRIKGVSRPALAPIMPGKNGPFMIIDCGANAECKPSNLVQFAKMGEIYFENILNVKNPTVGLINIGSEEEKGNELTKEAHKLLKDMDFNFVGNVEPRDIPTGNTNVLVCDGFVGNTVLKMYEGVASTIFETLKDEIMSSFRTKIGGLLLKPVFKKFKKDYDYKEYGGAAFLGVDGICIKAHGSSDDKAFKNAIKQAINFYENGIIDKIKSHIEQKMI
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TSAD_STRS2
Sequence: MMKDRLILAIETSCDETSVAVLRNDAELLSNVIASQIASHQRFGGVVPEVASRHHVEVITACIEEALLEAEVTAEDLTAVAVTYGPGLVGALLVGISAAKAFAWANGLPLIPVNHMAGHLMAARAVKELEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLPYPAGRVIDELAHEGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLYHNAQQKGETLSNADLSASFQACVMDILMAKTKKALEQYPVKTLVVAGGVAANQGLRERLAAEITDVEVIIPPLRLCGDNAGMIALAAVSEYNKENLAGWDLNAKPSLAFENL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRE7_YEAS7
Sequence: MIEERDLVLSNGIHCIADIHSELYARLKKESQAVTPWVYQKQYGKFVTYFVAVIIFLSLIKKLAFMYYDSSEEFLPEKKNSPTTPSVFLARIMTKLVAFNRYICYRKFPTLIFSYLGIPTSVGTFLVVMATTLYTLLYCFVPHPFYRPCAGFGSPPLSVRAGIMAISLVSFVFSLSGKINVIGWLVGLSYEKINIYHQWASILCLFFSWVHVIPFLRQARHEGGYERMHQRWKASDMWRSGVPPILFLNLLWLSSLPIARRHFYEIFLQLHWILAVGFYISLFYHVYPELNSHMYLVATIVVWFAQLFYRLAVKGYLRPGRSFMASTIANVSIVGEGCVELIVKDVDMAYSPGQHIFVRTIDKDIISNHPFSIFPSAKYPGGIKMLIRAQKGFSKRLYESNDDMKKILIDGPYGGIERDIRSFTNVYLICSGSGISTCLPFLQKYGPILHKTNLEVITLDWVVRHREDISWIRDEICTLSNNLRQLFLDGTIVVRIYVCSDSTVPGIIKTFPQTADTASDQSDLAKREKDTEFGQDDTESNSTFDKSNNEYKGLITIIPSKPDLNQVINDYQIGFRNCFICSGSDSLRYTVGNSVAGLQAKVFSNKNVEECYLHSESFGY
What is the function of this protein?
Cell surface metalloreductase.  May be involved in copper homeostasis (By similarity).
What are the official names of this protein?
Ferric/cupric reductase transmembrane component 7, Ferric-chelate reductase 7.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGM1_MOUSE
Sequence: MEGPRSDVGRWGRSPWQPPTTPSPEPEPEPEPDRRSRSRRGGGRSFWARCCGCCSCGNRGDDDWGPEPSGSRSRGTSSRGRDSRGGRRPESRGSGVNAAGDGTIREGMLVVTGVDLLCSRSDQNRREHHTDEFEYDELIVRRGQPFHMILFLNREYESSDRIALELLIGSNPEVGKGTHVIIPVGKGGSGGWKAQVTKNNGHNLNLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGFATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESVKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAIHSNNREDITHIYKHPEGSEAERRAVEKAAAHGSKPNVYATRDSAEDVAMQVEAQDAVMGQDLAVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKEAKKEVTLAPGASDSVTMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECGVQIVFKNPLPVTLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPASGGSGFSDAGGDSRSGENIPMAYRGGA
What is the function of this protein?
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.  Responsible for cross-linking epidermal proteins during formation of the stratum corneum.  Involved in cell proliferation (By similarity).
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase K, Epidermal TGase, Transglutaminase K, TG(K), TGK, TGase K, Transglutaminase-1, TGase-1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: CSTF2_HUMAN
Sequence: MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSMNQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSMERGQVPMQDPRAAMQRGSLPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRGPPLDGRGGRDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPVPGPRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQGASIQGGSQPGGFSPGQNQVTPQDHEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAP
What is the function of this protein?
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.  This subunit is directly involved in the binding to pre-mRNAs (By similarity).
What are the official names of this protein?
Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64.
Protein: PHS_PHOPR
Sequence: MSNLHELKCEACHIDAPKVTDLELEEMLQGISQWRVIERDGIKQLEREFTFKNFKLAWAFSNKIAELAEAEFHHPTITLEWGKVTVCWWSHSAKGLHKNDFICAAKTDRCLE
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PURA_GEODF
Sequence: MANVVVVGAQWGDEGKGKVVDIYTEFADDVVRYQGGNNAGHTLVVGDEKIVLHLIPSGILHKGKRCIIGNGVVLDPEVFIREITNLKAKGKFQDDGVLLLSESLHIIMPYHKRIDIAREAKSGAKKIGTTGRGIGPAYEDKIGRRGIRLMDLLDKQVFTRKLKESLEEKNFLLEKMLGEKPFSFEEIFDEYSAFADTLRTYVADTTLVLHQDLKAGKKLLFEGAQGTLLDVDHGTYPYVTSSSTCAGGACTGTGASPRDINEIIGISKAYVTRVGSGPFPTELEDADGEKLRQTGGEFGATTGRPRRCGWFDALVIKYAVRVNGLTGIALTKLDVLSDFETIKICTGYSYNGKFLSELPANLDIFEKCQPVYEEMPGWQTDITAARSFDDLPEKARTYVKRLEELAGCPIVLVSVGPRRDQTIMLKNPFEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_RHOPA
Sequence: MPADIRIVPCLTDNFGYLVHDPATGATASIDAPEAAPLIAALDKEGWKLTDILVTHHHGDHVGGIAELKKKYQCRVHAPHDANAKIADADVRLQEGDVVRVGDLTARVLETPGHTLDHLSYVFDDDRALFAADTLFSIGCGRVFEGTYPMMWESLLKLRALPDDFKLYCGHEYTASNVKFALGIEPDNAALQARAKQVESLRAEGKPTIPVTLGEEKQANVFLRADVPSVAAAVGMPGAPAAEVFGEIRERKNNG
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DTLA_XENLA
Sequence: MLFRSVMNKPRLGYGQKGAPFTYPLQSLLQCYQCVKQDEHISYGELGMPVPPFGCAFSTVPDMSHVLAVANEEGIVRLYDTECRDMQRLLMKEFMAHTNAVFDIAWVPGEHKLVTASGDQTAKLWDVMAGELIGECRGHQCSLKSVSFSKFERAVFSTGGRDGNIMMWDTRCSKKDGFYRQVNQITGAHNAIDKQTPSKMKKRKPSIRGLAPSVDSQQSVTVVIFQDEYTIISAGAVDGVVKIWDLRKNYSAYRQDPVPVKHFPYPGNSTRKLGYSSLVLDPTGTNLFASCTDDNVYMFNATGLKTDPVSIFRGHQNSTFYIKASVSPDGQFLLSGSSDHSAYIWQVSDPMAAPVTLMGHCQEVTSVAWCQSDFTKIATCSDDNTVRVWRLKRSCEDSSESDKRDSVGWACKKKFEPSSMAANLCTPGKPSVMSSSSLTSSPTPASCAPSNTGDLPMPSSTPISALLPDPKLQTPKRINNGGLGVSPKQMSSSKMSIKDWVTRTPKSSTRTDTKTPSPRKAFTPVEQYPSVSSARVQLPYEKRAKRRLETSSEYAEHVCPDNCNCVRELEPGLKKAKLDVCFIDKERDSSDDKCLRLSDLSKGFDQELSPSPSTSLHMNATENLLQLGPLSELKSVLLDKENSSPEKNWLSALGHKFKSSPQNKASGSPSSRTSTTKKQQPRNAPNSPVSVPTPPGSMRKICTYFFKKSE
What is the function of this protein?
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis.  The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2.  CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication.  CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing.  KMT5A degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration.  Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation.  In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.  May play a role in the regulation of the circadian clock (By similarity) (PubMed:19595719).
What are the official names of this protein?
Denticleless protein homolog A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat cdt2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
Protein: MURD_PARUW
Sequence: MPIENYFGKKALIIGLGVSGRAAASFLQTSGVKVLGVDRDYLQLENQPEILELKAKGLVIQADCETIDLKTFDLIVVSPGIPSNHPLIKKAHEHKKEVIGEIELGCRASCHSIIGVTGTNGKTTVTLLITHILNANGLKAKALGNVGTPLTREILTLDFQEIAVLELSSYQLDTFQQQVLDEAVVLNITPDHLERYETMENYAKSKFQIGKCLKKSGKLFVERKAAVEYQHLLNFPHSTYGYLPSCHTYTDLCSVFLEGMQQFELPLEWQGKENHDLENLLAAYAICARRGIKPQQFLQALKTFQKPSHRVEFVLEKNGIHFYDDSKGTNIDAVMRAVQSINRPVFLIAGGVDKGASYVAWLNVFKGHVKKVYAIGQAANKIQKELSLHIRVQIEANLDDAVKQAYQDAKEGDAVLLSPGCASFDMFKDYIHRGEEFKRLVKLL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_FRATO
Sequence: MAAEGRVQRVASEFQKVISLLLRTRIKDAKLASATITEVDLSKDLSYAKIYYTCLAIEDAEYIDKAFEKSKGFFRSSIAKSLSLRIVPNLKFIYDTSLDYGMQMEEKIQQALEADSKIIKQDDKSLQENYKQNDKETKAEKLR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_COXBN
Sequence: MAHKKAGGSTRNGRDSNPKMLGVKRFGGERVLAGNIIVRQRGTHYRPGENMGMGRDHTLYALIEGKVKFIRKGPKKRNFVSIEPLEESQP
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: TOLB_CHLPN
Sequence: MLRQLCFQVFFFCFASLVYAEELEVVVRSEHITLPIEVSCQTDTKDPKIQKYLSSLTEIFCKDIALGDCLQPTAASKESSSPLAISLRLHVPQLSVVLLQSSKTPQTLCSFTISQNLSVDRQKIHHAADTVHYALTGIPGISAGKIVFALSSLGKDQKLKQGELWTTDYDGKNLAPLTTECSLSITPKWVGVGSNFPYLYVSYKYGVPKIFLGSLENTEGKKVLPLKGNQLMPTFSPRKKLLAFVADTYGNPDLFIQPFSLTSGPMGRPRRLLNENFGTQGNPSFNPEGSQLVFISNKDGRPRLYIMSLDPEPQAPRLLTKKYRNSSCPAWSPDGKKIAFCSVIKGVRQICIYDLSSGEDYQLTTSPTNKESPSWAIDSRHLVFSAGNAEESELYLISLVTKKTNKIAIGVGEKRFPSWGAFPQQPIKRTL
What are the official names of this protein?
Protein TolB homolog.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y3291_ACIBY
Sequence: MIHHIPNVLSKEQVQYFRNEMDKIEWVNGKVTAGTLSATVKRNQQLPEDHPLTHHLSNIILEALGTHPLFLSAAIPLDIIPPLFNRYENQESFGFHVDNSIRRIRGTNERLRTDLSCTLFLSEPEEYEGGDLVVEDTYGYHEVKLPAGDMILYPSTSLHEVTAITSGCRIASFFWVQSMVRDDAERHMLFNLDQTVQNLRMQLGDNHSEVIKLTNLYHNLMRKWAEL
What are the official names of this protein?
PKHD-type hydroxylase ABAYE3291.
Protein: RPOC_NEIG1
Sequence: MNLLNLFNPLQTAGMEEEFDAIKIGIASPETIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKFKGVTCEKCGVEVTLSKVRRERMGHIELAAPVAHIWFLKSLPSRLGMVLNMTLRDIERVLYFEAFVVTDPGMTPLQRRQLLTEDDYYNKLDEYGDDFDAKMGAEGIRELLRTLDVAGEIEILRQELESTGSDTKIKKIAKRLKVLEAFHRSGMKLEWMIMDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELHAPDIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIFHKLEKQGLASTVKAAKKLVEQEVPEVWDILEEVIREHPIMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTRDRINAKGEGSLFADVKEVHRAYHTKQVELGTKITVRLREWVKNEAGEFEPVVNRYETTVGRALLSEILPKGLPFEYVNKALKKKEISKLINASFRLCGLRDTVIFADHLMYTGFGFAAKGGISIAVDDMEIPKEKAALLAEANAEVKEIEDQYRQGLVTNGERYNKVVDIWGRAGDKIAKAMMDNLSKQKVIDRDGNEVDQESFNSIYMMADSGARGSAAQIKQLSGMRGLMAKPDGSIIETPITSNFREGLTVLQYFIATHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSDGFVMKAVVQGGDVIEALRDRILGRVTASDVVDPSSGETLVEAGTLLTEKLVDMIDQSGVDEVKVRTPITCKTRHGLCAHCYGRDLARGKLVNAGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQVEAKSNGTARFSSQMRYVANNKGELVVIGRSCEVVIHDDIGRERERHKVPYGAILLVQDGMAIKAGQTLATWDPHTRPMITEHAGMVKFENMEEGVTVAKQTDDVTGLSTLVVIDGKRRSSSASKLLRPTVKLLDENGVEICIPGTSTPVSMAFPVGAVITVREGQEIGKGDVLARIPQASSKTRDITGGLPRVAELFEARVPKDAGMLAEITGTVSFGKETKGKQRLIITDVDGVAYETLISKEKQILVHDGQVVNRGETIVDGAVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKISDKHIEVIIRQMLRRVNIADAGETGFITGEQVERGDVMAANEKALEEGKEPARYENILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKQDELRGLKENVIVGRLIPAGTGLTYHRSRHQQWQGVEQETAETQVTDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CIRA_CHACT
Sequence: GIPCGESCVWIPCISAALGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Circulin A, Cyclotide cir A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SCRB1_RAT
Sequence: MGVSSRARWVALGLGVLGLLCAALGVIMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPSEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSYIENRSLRFQPDRSQGSESDYIVLPNILVLGGAVMMEDKPTSLKLLMTLGLVTMGQRAFMNRTVGEILWGYEDPFVNFLSKYFPDMFPIKGKFGLFVGMNDSSSGVFTVFTGVQNFSKIHLVDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSQPHFYNADPVLSEAVLGLNPDPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQSGMMGGKTLNTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIIYQLRSQEKCFLFWSGSKKGSQDKEAMQAYSESLMSPAAKGTVLQEAKL
What is the function of this protein?
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells.  Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux.  Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL.  May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.
What are the official names of this protein?
Scavenger receptor class B member 1, SRB1, SR-BI.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
Protein: S1_BPMU
Sequence: MFYIDNDSGVTVMPPVSAQRSAIVRWFSEGDGNNVITWPGMDWFNIVQAELLNTLEEAGIQPDKTKLNQLALSIKAIMSNNALLIKNNLSEIKTAGASAQRTARENLDIYDASLNKKGLVQLTSATDSPSETLAATAKAVKIAMDNANARLAKDRNGADIPNKPLFIQNLGLQETVNRARNAVQKNGDTLSGGLTFENDSILAWIRNTDWAKIGFKNDADSDTDSYMWFETGDNGNEYFKWRSKQSTTTKDLMNLKWDALSVLVNAIVNGEVISKSANGLRIAYGNYGFFIRNDGSNTYFMLTNSGDNMGTYNGLRPLWINNATGAVSMGRGLNVSGDTLSDRFAINSSNGMWIQMRDNNAIFGKNIVNTDSAQALLRQNHADRKFMIGGLGNKQFGIYMINNSRTANGTDGQAYMDNNGNWLCGAQVIPGNYANFDSRYVRDVRLGTQSLTGGLSRDYKAPSGHVITGFHTNGDWEMQGGDDKVYIRPVQKNINGTWYNVASA
What is the function of this protein?
Component of the tail fiber that acts as receptor binding protein.  Binds to the primary receptor, thereby determining the host range.  Two alternate tail fiber S and S' proteins are encoded extending the host range of the virus.
What are the official names of this protein?
Tail fiber protein S, Gene product 49, gp49, Gene product S, gpS.
What is the protein family that this protein belongs to?
Belongs to the caudovirales tail fiber protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Tail fiber.
Protein: DAPE_MARMS
Sequence: MSPTLKLALDLISRPSVTPEDAGCQDLMIERLKNIGFEIEYMPFGEVKNFYAKRGNSGPNLCFAGHTDVVPTGPEAEWKIPPFAPEIVDGVLYGRGAADMKGSLAAMVTAVENFVAKHPNHSGQISFLITSDEEGPFVDGTTRVVDALMERNEQVDWCIVGEPSSTKTLGDIIKNGRRGSFSGDLTVYGKQGHVAYPHLAENPIHLAAPALAEMASSHWDDGNDFFPPTSFQVSNIHSGTGATNVVPGKLNAQFNFRFSSELDFDALKVRVIEILDKHNLRYDIEWTYNGLPFLTRPGELVDAIVEAVQATVNITPELSTSGGTSDGRFIAKMGTQVVELGPINATIHQINECVDAESLNQLSEIYARILENLFAKK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PYRG_ECOSE
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TEBP_PONAB
Sequence: MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE
What is the function of this protein?
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).  Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.  Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
What are the official names of this protein?
Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: CHBG_ECOSM
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRADRQMVFDLPVNLRTTQGFSSAFYGEEISESLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSAYCFPRLTELDVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP4_RAT
Sequence: MSERQSAGATNGKDKTSGDNDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS
What is the function of this protein?
Functions as a modulator of calcium-binding by calmodulin.  Thereby, regulates calmodulin activity and the different processes it controls.  For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways.
What are the official names of this protein?
Calmodulin regulator protein PCP4, Brain-specific polypeptide PEP-19, Purkinje cell protein 4.
What is the protein family that this protein belongs to?
Belongs to the PCP4 family.
Protein: RS6E_THEGJ
Sequence: MATFKVVISNPKNGIARQIEISGDAAEKLIGKRIGDEIPVKELGINLSEIFGQEIPEDAKLKIKGGTDKDGFPMRPDVHGPRRVRILLSRGPGFRPKEKGERRKKTVRGNTISPEIVQINAVLVF
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.