PharMolix/UniProtQA huggingface dataset:
Protein: KLF6_RAT
Sequence: MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDNQEDLWTKIILARERKEESELKISSSPPEDSLISSGFNYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPIGEVLVNSGNLSSSVISTPPSSPEVNRESSQLWGCGPGDLPSPGKVRSGTSGKSGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL
What is the function of this protein?
Transcriptional activator.  Binds a GC box motif.  Could play a role in B-cell growth and development (By similarity).
What are the official names of this protein?
Krueppel-like factor 6, Core promoter element-binding protein, Transcription factor Zf9.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_CHLMU
Sequence: MEPYAVVQTGNKQYQVRKGDVIDVELLDGISEENKEVLFQEVLFVFDGEKASVGSPTVGNAVVKGELISFVRGEKVVAYKYKKRKNYHKKIGHRQNYLRVKICDLVM
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MECA_STAES
Sequence: MRIERVDDTTVKLFITYSDIEARGFSREDLWSNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDAMNMSDDDTNHQFDDQVNELLAQTLEGEESLEDLFEQRKQQKKNHQDKQQRRAHKPSNVRNIIVKFDDLEQVIDYAYHNNQNTDEFEDLLYMIDNKYYYSIHFDDSVSQEMINDSYSQLLEFAYPTDKTNIYLNDYAKIIMSHNVTSQVRKYFTDTNE
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: RNS10_RAT
Sequence: MKVTLVHLLFMMLLLLLGLGVGLGLGLHMAAAILENQPLDEFWPSDSQDTAEATEEGQGTRTTEALVLDNKEMAVPVWSEDTVLSEDEVGGSRMLRAKTLLQSKQGYLKFDLNIRDCNVMMAHKIKEHNQSCINDYTFIHEDPSTVGAVCNSPLVDCDLKGGKCHKSPRPFDLTLCKLAKPGQVTPNCHYLTYITEKVIIITCNNTKQLEIK
What is the function of this protein?
Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility.  May be involved in sperm adhesion to the egg zona pellucida.  Does not have ribonuclease activity (By similarity).
What are the official names of this protein?
Inactive ribonuclease-like protein 10, Protein Train A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURR_SALNS
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: Y8993_DICDI
Sequence: MSQNNLKFTEFLSNVKSKANSKGFMKLFDMYHRQVVVKKPFSFLVHIMCGLTLTSYVIRHDKVEHHKTQPYH
What are the official names of this protein?
Uncharacterized protein DDB_G0276837.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MAFB_RAT
Sequence: MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQPLQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHAAAAATAAGSNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSDSPSSPEFFL
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells.  Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation.  Involved in renal tubule survival and F4/80 maturation.  Activates the insulin and glucagon promoters.  Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element.  SUMO modification controls its transcriptional activity and ability to specify macrophage fate.  Binds element G1 on the glucagon promoter.  Involved either as an oncogene or as a tumor suppressor, depending on the cell context (By similarity).  Required for the transcriptional activation of HOXB3 in the rhombomere r5 in the hindbrain (By similarity).
What are the official names of this protein?
Transcription factor MafB, Maf-B, Transcription factor Maf-1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_ACIET
Sequence: MASGKPKKKNPRLASGRKRARQGLKLNAANTSLRSKYRTAVKNVEKAVLAGDKTKATELFAKAQSVLDTIADKGIFHKNKAARDKSRLSAKVKALALAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: KHDC3_RAT
Sequence: MATLKTFRTLVQLKHKLGKAYEIVGEPRLPKWFHVEYLEDPKKMYVEPTLVEIMFGKDGEHIPHVECTLHVLIHVNVWGPEKQAEILIFGPPNFQKDVAQMLSNVAHFCRMKLMEKEALEAGVERRLMAASKATTQPTPVKVRDAATQVAPVQVRDAAIQPAPVKVRDAATQVAPVQVHEVATQPVPVQVRDAATQPVPVRVRDAATQPVPVRVRDAATQPVPVRVRDAATQPVPVRVRDAATEPVPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVREAATQQTPVEVADDTQLVQLKAGEAFAQHTSGKVHQDVNGQSPIEVCEGATQRHSVDASEALSQKCPEDLEGGDTETSLDDSYVIIRPSRAVWEPFVML
What is the function of this protein?
As part of the OOEP-KHDC3 scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart (By similarity).  Regulates homologous recombination-mediated DNA repair via recruitment of RAD51 to sites of DNA double-strand breaks, and sustainment of PARP1 activity, which in turn modulates downstream ATM activation (By similarity).  Activation of ATM or ATR in response to DNA double-strand breaks may be cell-type specific (By similarity).  Its role in DNA double-strand break repair is independent of its role in restarting stalled replication forks (By similarity).  As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for maintenance of euploidy during cleavage-stage embryogenesis (By similarity).  Required for the formation of F-actin cytoplasmic lattices in oocytes which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning (By similarity).  Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process (By similarity).  Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function (By similarity).  Promotes neural stem cell neurogenesis and neuronal differentiation in the hippocampus (By similarity).  May regulate normal development of learning, memory and anxiety (By similarity).  Capable of binding RNA (By similarity).
What are the official names of this protein?
KH domain-containing protein 3, Protein Filia.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome. Note=Localized to centrosomes during interphase and mitosis (By similarity). Localizes to sites of DNA double-strand break repair (By similarity).
Protein: TBA8_HUMAN
Sequence: MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEGEEF
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-8 chain, Alpha-tubulin 8, Tubulin alpha chain-like 2.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LEPA_HELPG
Sequence: MKTKAPMKNIRNFSIIAHIDHGKSTLADCLISECNAISNREMKSQVMDTMDIEKERGITIKAQSVRLNYTFKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANVYIALDNNLEILPVINKIDLPNANVLEVKQDIEDTIGIDCFSANEVSAKAKLGIKDLLEKIITTIPAPSGDFNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIVSLGLKSVTDIAVGDTLTDAKNPTPKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERLEREFSLNLIATAPTVVYEVHLTDNSVKYVQNPSELPPENHIACIKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDKLKSCTKGYASFDYEPIENREAHLVKLDVRVAGDVVDALSIIIDKNKAYEKGRALVETMKELIPRQLFEVAIQASVGNKIIARETIKSVGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVELPQEAFLAILKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IOLB_GEOKA
Sequence: MSRLIIPSHSPNEEGNVVRVTPESVGWEYVGFEVYVLAKGQTLRKETKDQEACLVLLKGKANISTKLERWEQIGLRMDVFEKVPPYSVYVPANDVYEVEAMTDVEVAVCLAPGKGTYPARLIPPSEVGVEIRGAGNIERRVHNILPESQPADSLLVVEVFTPEGNWSSYPPHKHDQDNLPHESYLEETYYHKINPGHGFMVQRVYTDDRSIDETMVVKNGDVVLVPKGYHPVSAPPGYEGYYLNVMAGPVRTWKFHNDPDHDWVMESKLAAKQKEK
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.
Protein: RPPH_ACIBT
Sequence: MIDSEGFRPNVGIILANDDGQVLWAKRIGHNAWQFPQGGIQFGETPEQALFRELREEIGLLPEHVQIIAQTKGWLRYRLPHRYIRSDSDPVCIGQKQKWFLLKLTAPAKNIQLNLADPPEFDEWQWVSYWYPLGQVVNFKRDVYRKAMVELCTQLPVQQLP
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: COX2_ROULE
Sequence: MAYPFQLGFQDATSPIMEELLHFHDHALMIVFLISSLVLYLISVMLTTSLTHTSTMDAQEVETIWTILPAMILIMIALPSLRILYMMDEINNPYLTVKTMGHQWYWSYEYTDYEDMSFDSYMVPTQDLKPGELRLLEVDNRVVLPMELTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLLSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSSSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL3_YERPN
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GLYA_STRPM
Sequence: MTMIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVMAAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQANAAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAILEQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPVHYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFKEALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQNLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVNHDQETILEEVRQEVRQLTDAFPLYKK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_DESVM
Sequence: MSRTSLEVKAQRKPKFSARAYNRCPVCGRPRAYMRKFGLCRICFRNMALRGELPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RX_DROME
Sequence: MSGSGGVANSSSTAAANNTAATFQHIFEQLVQQGGGNHKLPPKQLEQLRHLLGNVRDAKNLQMIVEKFKNLEQFHEHYAAHLANNNTVISTEDSNDLVKDNARKYGSGGQTLTPRHTIDAILGLKNRNGAANGSGRNPETVSDGSVDPSLGDDDATDLRCGMTLTQLRSMDNHMASMLQQHAKNGGALPYGPPTPPGGQQPQVPNATPLHHGQQMGGQAGHATHAGHGHPTHHGHAPFGYHNAFGFGQGGHGYGHPEEAAGNYLNSMHQMVEANQLQTGANGANPPPAPLPPSSFGSHQQHLAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINYDERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIRPRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSGPDVCMSPQNLSIGNADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGRDSPPPPPTPTGKGSSTPPTDMRSNSIATLRIKAKEHLDNLNKGMVSIV
What is the function of this protein?
Appears to function in brain development.
What are the official names of this protein?
Retinal homeobox protein Rx, DRx, DRx1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HXA3A_TAKRU
Sequence: MQKATYYDSSAIYSGYPYQSANGFSYDANQIQYPRTSHVESEYHRPACSLQSPGGSVALQKREMAAENCDRTTAVQAVQSKVHPESNQPQVPVSAPPPPPQSPGAISQTTSNGSNQPTAKNSSPTSASRGKQIFPWMKESRQATKQKSTSNTSSVESCPGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGAGMMPSPGGQSPRSPVGPGSTGAGGGGYLNSMHSLVNSVPFESQSPTSYNKPHQNAYGMATSYPPPLSSSHNNCPPTQKRYAGTDSATPEYDAHPLQGNGSYGTHMQGSPVYVGGGYIDSVPNSGSSVFGLTHLPHPPSANMDYNGAITMGNSQHHGVCDPTPTYTDLTSHYSQGRIQEAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A3a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL32_MYCGI
Sequence: MAVPKRRMSRANTRSRRAQWKAEATGLVSVTVAGQPRKVPRRLLKAARLGLVDLDRR
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NSCA_NEOFI
Sequence: MATPRGQTVWFGNEFPNDDLKDLFRRLHQHSKDRRFRLLSVFLDESTAILKEEVANLPQQLQELVPHFDTACTLPEVDFRQGPLGAAMESALLTILELGMLIGNYEAEDIEWDLDPSQTILAGLSIGIIAGAAVALSSSLADVAKVGAESVRVSFRLGVYVADISTKLEAPQSDGTLQSWAHVVTGMSHEAVQEELSQFNAVTQNPEITKVFVSAADKTSVSVTGPPSRIKAAFQHSPSLRYSKSLPLPVYDGLCHAPHLYSQDDIEIVINSAKSVIPTSRPVRLPLISSQTGKPFEAKTAGELFLEIGTELLTGTIYLDNVTAGILEHVKLKEPTGNYQIISFRMSQVLNGIQAAIETDFPALGRARRDLVSWVHGDYGARRPSSYAASKLAIVGMACRLPGGANDPELFWELLEQGRDTLTTVPPDRFDLNTHYDPTGKTENATQTPFGNFIDRPGYFDAGFFNMSPREAEQTDPMHRLALVTAYEAMEMAGLVPGRTPSTRPNRIGTFYGQASDDWRELNASQNISTYAVPGGERAFANGRINYFFKFSGPSYNIDTACSSGLAAVQAACSALWAGEADTVIAGGLNIITDPDNYAGLGNGHFLSKTGQCKVWDKDADGYCRADGIGSVVIKRLEDAEADNDNILAVVLGARTNHSAEAVSITHPHAGAQKANYRQVLHQAGVNPLDVSYVELHGTGTQAGDAVESESVSDVFAPSMPRRRPDQRLYLGAVKSNIGHGEAAAGIASLLKALLVYQKNMIPKHIGIKTEINPIIPKDLDRRHVGLAMSNTPWPRPAGKKRLAVVNSFGAHGGNTTVLLEDAPERVKVSTQDDRTTHPVVISAKSKKSLQANIEKLLSWLDQNPDADLADLSYTLCARRMHHSMRFGAAASDIAALQKTLRSWLDSPKASTELRAIPNDAPSVVLTFTGQGAYYSGMGRELFAEFSYFRTQVLQLDQIAQRLGFPSVVPVIDGSIDDGPASPILTQLSVVVLEIALARFWSHLGIRISAVVGHSLGEYAAFAVAGVISAADALYLVGRRAQLTEERCTQGSHSMLSVRASEDDIEELIAGSPDTAEIAYEVCCRNTPQDTVIGGTKESIDRIRQALEANSIKCTQLDVPFAFHTAQMDPILDSLETLATPIAFKAPSIPVLSPLLGSVVFDRKSIHAQYLRRATREAVDFVAAIEAAQDFGLVDAKTIWIDVGPHPICAGLVRGIDSSASVISSCRRNEDNLATMSKSLVTLHLAGLTPCWAEYFRPREREYSLLKLPTYSWNETDYWIPYIGTWTLDKALLKYGEKKAPLSLAMSRPSALRTSLVHQITAETVEATTATLHVLSDMQHPDFLEALHGHRMNNCGVATSSIWSDMAFTVGEYLYRRLVPQVKDVHMNLSDFEVLHAQVALEKKGSVQPLVLKAHLDLSTSSMSLTWFNASAETGECAAESFATGVVRFEDPAAWTREWDRLSHLVLGRIEALEQRAAEGKASKLSKPLAYALFKNVVDYADRYRGMDQVVLHEHEAVAEVTLVAERHGTWHTPPHWIDSVSHLAGLVMNGSDASNTRDYFYVTPGCSSFRLLNPLKAGGKYRSYVRMFPLLEEANMYAGDVYILQGEQIVGMVGQIRFRRVPRLLMDRFFSPAAASHAEKQLQETAPSATSVKKSTPPAAEAPASVPALLSNPVAIPFPAASKSEVSTPPLTPPSQQESPGESAVITPATSDRGDPVDAGVVGQCLQVMARETGLEVDALTPDASFVQLGIDSLMSLVLSEKFRAELGIEIKSSLFLECPTIGEMTAWLEEYC
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of neosartoricin, a prenylated anthracenone that exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576, PubMed:23368997).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (PubMed:23368997).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (PubMed:23368997).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (PubMed:23368997).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (PubMed:23368997).  There is no gene encoding O-acetyltransferase in the nsc gene cluster; thus, the last step of 2-O-acetylation leading to neosartoricin may be catalyzed by an unidentified O-acetyltransferase (PubMed:23368997).
What are the official names of this protein?
Non-reducing polyketide synthase nscA, Conidial yellow pigment biosynthesis polyketide synthase nscA, Neosartoricin biosynthesis protein A.
Protein: RL18_CAUVC
Sequence: MALSPRESAAKRAQRVRTRLKSLANGRPRLSVFRSSKNIYAQVIDDERGVTLASASTLEAEGKGADKDAAAAVGKLVAERAIEKGVKDVVFDRGSYIFHGRVKALADAAREAGLNF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: P2C46_ARATH
Sequence: MLSTLMKLLSACLWPSSSSGKSSDSTGKQDGLLWYKDFGQHLVGEFSMAVVQANNLLEDQSQVESGPLSTLDSGPYGTFIGIYDGHGGPETSRFVNDHLFQHLKRFAAEQASMSVDVIKKAYEATEEGFLGVVTKQWPTKPQIAAVGSCCLVGVICGGMLYIANVGDSRAVLGRAMKATGEVIALQLSAEHNVSIESVRQEMHSLHPDDSHIVMLKHNVWRVKGLIQISRSIGDVYLKKAEFNKEPLYTKYRIREPFKRPILSGEPTITEHEIQPQDKFLIFASDGLWEQMSNQEAVDIVQNHPRNGIARRLVKMALQEAAKKREMRYSDLKKIERGVRRHFHDDITVVIIFLDTNQVSSVKGPPLSIRGGGMTFPKKI
What is the function of this protein?
May dephosphorylate and repress plasma membrane H(+)-ATPases (PM H(+)-ATPases, e. g.  AHA1 and AHA2), thus influencing negatively plant growth and fitness.
What are the official names of this protein?
Probable protein phosphatase 2C 46, AtPP2C46.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RSD_YERPY
Sequence: MLNRLESLTQRVGGSNELIDQWLHARKELLVSYCTVIGIKPQKEKHTPLNAKTLENFCHNLVDYLSSGHFHIYDRIIKEVEGASSPKMALTAKIHPALKNNTQTIMAFHDRYTNIEIDDDSCTEYQQALSDIGEALDARFKLEDQLIQWAAESWQAAQLADADKKSQVN
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.