PharMolix/UniProtQA huggingface dataset:
Protein: SECA_RICAH
Sequence: MLSILKKLFGTANDRTVKKLFSEITKINSLEHAIQKLSDEELKNKTVEFKEKLKNGATLDDIVYEAFAVVREAARRVCGMRHFDVQLIGGLILHRGMITEMRTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLARRDSAAMGKIYNFLGLSVGCIVAGMPDEAKRAAYNADITHATNNELGFDYLRDNMKYSLQERVLRPFNFAIIDEVDSILIDEARTPLVISGPVNDNSELYGKIDKIVRLLNINDFEKDEKLKTINLTETGITHIESLLSKEGIIKPDTGLYDFENLTLVHYVNQALRAHNMFTVDVDYLVREGKVMIIDEFTGRVMEGRRYSEGLHQALEAKENVKIQNENQTLASVTFQNYFRNYPKLSGMTGTAMTEAPELKDIYNLDVVAVPTHNKVTRLDLDDEIYGSKKEKYDAILKLIKDCYDRGQPILVGTISIEKSEELSSVLNAEKIPHKVLNAKFHEQEACIIAQAGRFKAVTIATNMAGRGTDIMLGGNPEMLIEHLDKDHNYAAKIDEIKAQIAEEKKQVIEAGGLFVIGTERHESRRIDNQLRGRSGRQGDPGKTKFFLSLDDDLMRIFASDRISGVLRTLGLKDGEAIQHPMISRSLEKAQQKVEGYNYEMRKNLLRFDDVMNDQRKIIYEQRTEIIKSKDSYGFLNSTTEELAKKIVLAFMPVGSYREDWDIENLSVELHRVFAIKFDHNLVSKSDVTEEEITKIVIQMAHDVYKSKEEAYSSELMHNAVKYILLTTLDQVWKDHLYSLDHLRQGISLRAYAQKDPLSEYKREAFNLFEQMLNNLKELFIQAVYHFHIDLKHVQKEDVSLERKKLQNNMRESREDPAFSKYNAGSSLETHLKPVVSRIDPKDRNPDDPTSWGRVSRNELCPCSSGKKYKYCHGAHE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y280_METAC
Sequence: MNVDSRVFRFFLVFLILVVVASPGCVDNQPEPGNTSAGEGEVLTVFHAGSLSVPFEELEAEFEAQHPGVDVQREAAGSAQSVRKITELGKKADVLASADYALIPSLMVPEYADWYAAFARNQMILAYTNESKYGDEINTDNWYEILRRPDVRYGFSNPNDDPAGYRSQMVTQLAESYYNDDMIYDDLMLANTGMTLTTEENGTALIHVPASEEISPNTSKIMLRSMEVELSSALETGEIDYLYIYRSVAEQHGFEYVALPPAIDLSSLEYADNYSKVQVEMVNGEVVTGSPIVYGVTIPNNAENSELATEFVALLLGETGQQIFIENGQPPIVPAIAEGKDSMPEELQALVV
What are the official names of this protein?
Uncharacterized solute-binding protein MA_0280.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.
Protein: LPXH_PSEAE
Sequence: MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.  Can functionally complement lpxH deficiency in E. coli.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK16_LEMMI
Sequence: MLSPKRTRFRKQHRGRMKGTSYRGNHISFGRYALQALEPSWITARQIEAGRRAISRYARRGGKIWVRLFPDKPVTLRPAETRMGSGKGSPEYWVSVVKPGRILYEIGGVSENVARTAMLLAASKMPIRTQFIIEG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MVP_MOUSE
Sequence: MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMVTVPPRHYCIVANPVSRDAQSSVLFDVTGQVRLRHADQEIRLAQDPFPLYPGELLEKDITPLQVVLPNTALHLKALLDFEDKNGDKVMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIKQNQALRLRARKECFDRDGKERVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRARQNFKDLRGVAHRTGEEWLVTVQDTEAHVPDVYEEVLGVVPITTLGPRHYCVILDPMGPDGKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQPLEEGEGEEKVAHQAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPSGVEELLNLGHDPLADRGQKGTAKVLQPSAARNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVSLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPEETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFEMSEDAGPDGALLPRARDRAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYSRAQLELEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSPINLFNTAFGLLGLGSDGQPPVQK
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport.  Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK.  Down-regulates SRC activity and signaling through MAP kinases (By similarity).
What are the official names of this protein?
Major vault protein, MVP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS6_DELAS
Sequence: MRHYEIVLLIHPDQSEQVPAMLERYKGMITAGGGKVHREEDWGRRQLAYMINKLAKAHYLCLNIEADQAVMAELEHAFKFNDAVLRHLTVQKKKADTAPSSMMKTVEREEARKASQTEQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y1071_BURP1
Sequence: MPSFDVVSEANMIEVKNAVEQSNKEISTRFDFKGSDARVEQKERELTLYADDDFKLGQVKDVLIGKMAKRNVDVRFLDYGKIEKIGGDKVKQVVTIKKGVSGDLAKKVVRIVKDSKIKVQASIQGDAVRVSGAKRDDLQSTIALLRKEVTDTPLDFNNFRD
What are the official names of this protein?
UPF0234 protein BURPS1710b_1071.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CHTOP_RAT
Sequence: MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIWASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRSLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND
What is the function of this protein?
Plays an important role in the ligand-dependent activation of estrogen receptor target genes.  May play a role in the silencing of fetal globin genes.  Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.  Required for the tumorigenicity of glioblastoma cells.  Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH.  The CHTOP-methylosome complex associated with 5hmC methylates H4R3 and transactivates genes involved in glioblastomagenesis (By similarity).
What are the official names of this protein?
Chromatin target of PRMT1 protein, Friend of PRMT1 protein, Small arginine- and glycine-rich protein, SRAG.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus speckle. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (By similarity).
Protein: SYH_MESH7
Sequence: MKKKLNLCPKGTYDFFGQSAKIFIDVRKVFFDQAKKFNFSYIETPIFEYANIFLTTNQIADIVSKELYKFFDKSGRELALRPEGTAPIMRSVAQHKLFQTEKKFFYFGPMFRYENPQKGRFRQFYQAGFEIINYKKDSLEFQILEIIVLIKSIFKDLGINEYELKINFLSNLTTRNIYEKNLAQYFEKFSDKLEPISKIRIKKNPLRILDDKIEQEKEFVKLAPKINTFWTMEDKNIFNRITSILEEFKISYKVDYNLVRGLDYYDDFVFEFIDTSQTLGTKLALVGGGCYNNLPTKFGLNNFKSIGMAFGIERLIEIIKSKKNIKEQNLDFFLLSFTDKEILLNFKLAKILRKENFLVDLNKTPFSVSKGFQLAKKSGAKFVFFFEKNQAKNYISLKNLQTGKNEQILYTEINFEYLNSIIKASENA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_COXB2
Sequence: MNKIRKTFQYGKHEVTFETGEMARQATGAVVVRMGDTVLLVSVVAKKEAEEGRDFFPLTINYQEKTYAAGKIPGGYFKREGRPTEKETLTSRLIDRPLRPLFPKGFTNEVQVIATVLSVDSKVPTDIPAILGASAAIGLSGIPFNGSLGAARVGYRGGEYLLNPSLDELKDSALDLVVAGTRDAVLMVESEAQELPESVMLGAVLHGHQAMQVAIQAIAEFIQEAGGAKWEWEPPTVNTALEKWVVEKSEAPLKKAYQIQEKTARQAQIQAIRDQLLADRAAEREGEENAVNEHELAVIFHELERRIVREQILTGQPRIDGRDSKTVRPITVKVGVLPRSHGSALFTRGETQALVVTTLGTERDAQSIDDLDGDRQEEFIFHYNFPPFCVGEVGFMSGPKRREIGHGRLAKRAVVPVVPTLDKFPYVIRVVSEILESNGSSSMASVCGSSLALMDAGVPTKAPVAGIAMGLIKENDKYAVLSDILGDEDHLGDMDFKVAGTSNGVTALQMDIKIEGITKEIMEQALDQAKEGRLHILSIMNKVLDKPRSQVSDLAPQYVTMKINPEKIRDVIGKGGVVIREITEATNCAIDISDDGTIKIAAHTTEEGEAAKRRIEELTAEVELGKVYEGTVVKITDFGAFVQILPNTQGLVHISQIAQERVENVRDYLEEGQVIRVKVIEIDRQGRVRLSMKQID
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKT1_CAEEL
Sequence: MSMTSLSTKSRRQEDVVIEGWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPEPLNDFMIKDAATMLFEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAIESISKKYKGTNANPQEELMETNQQPKIDEDSEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEASEDNEDYDMG
What is the function of this protein?
Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway.  Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions (PubMed:9716402, PubMed:11747825, PubMed:11381260, PubMed:15068796, PubMed:18358814).  Plays a role in maintaining the gonadal basement membrane through it's role in inhibiting daf-16 activity (PubMed:22916022).  Has an essential role in regulating developmental arrest at the dauer stage (PubMed:10364160).  Plays a role in immune function and pathogen resistance (PubMed:18782349).  Regulates salt chemotaxis learning (PubMed:16950159, PubMed:30779740).  Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic development (PubMed:25383666).
What are the official names of this protein?
Serine/threonine-protein kinase akt-1, Protein kinase B akt-1, PKB akt-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
Protein: MURC_HYDCU
Sequence: MKDQVKQIHFVGIGGVGMAGIAEVCLNLGFTVSGSDLKENPTVRHLISLGALIQFNHDASHVKNSDVVVVSTAIAKDNPEVCFAKESRIPVIPRAAMLAELMRMRFGIAIAGTHGKTTTTSLASAILTEGGLDPTFVIGGKLNQFDSNARLGSSQYLIAEADESDASFLHLSPMMSVVTNIDEDHMETYQGDYANLEQTFIEFIHRLPFYGVAIVCIDDQNIQNMLPKLSRKIRTYGFSESADIRATEVLHQGLSMHFNVKANDLPEFSVVLNQPGKHNVLNALAAITVALELDVSIESIQKALAGFGGVGRRFEVYPSRSIGHKNVTLVDDYGHHPTELEATLSTARMAFPEKRLVLVFQPHRYSRTRDLFDEFVQALQHADLLVLLDVYPAGEAPIAAFDSKALLQAMRLRGHKENLHVESQQQLNELTETLLLDDDVVLVMGAGDVGQLARDWKQQAY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPH_KLEP3
Sequence: MNFLAHLHLAHLADSSLPGNLMADFVRGNPQGDYPAEIIDGIYMHRRIDVMTDNLAEVKEAREWFRPQTRRVAPITLDVMWDHFLSQHWAQLSPDLPLDEFVRYAEQQIVPILPDSPPRFVNLNQYLWSERWLERYQEMDFIQRVLNGMASRRPRLDALRDSWQDLDTHYDQLEGQFWRFYPQMMRLAENKQL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: RBFA_BORBU
Sequence: MYKNIKKFKLESFIAQEIGNLIVSGGIKDPRIHSFLTVVKVEFSKDLINAKVFMGSIKEGASLDNAVKALNNAKGFIQSQIIKRIKVRSTPKLLFVKDDSLSKSFYVNKLIEGLNTTREN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_CHLAT
Sequence: MAKNKGTRITITLECTNCKSNDLKRSPGVSRYTTQKNRRNTPNRLELKKFCSRCNQHTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SECF_ALIAD
Sequence: MKPRFDIIRASRWFFLLSGAITVAGVIVFALFGFNLSTDFKSGSEVQFELNQRVPEARVRQMFASIGLPLGDTSLTVGGIQQNVVMVTLPEQLTAKQISEIQAAEHRFFPDAKQDIQVNSVDPFVAEQTARKAVYAVLAAAACIVVYIAIRFEFRFAISGIIALLHDAFIVLAAFALLRREVDLTFVAALLTIVGYSINDTIVIFDRIRENLKIDKPETVDELRAVVNKSLWQVMNRSIRTVLTVLIAAVILYFFGGISIRNFTFALIIGLVSGAYSSIFIASPIWVAWRSRSMKKATRGDKAAPIPE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: O162_CONQU
Sequence: MKLTCVVIVAVLFLTALADDSRNGLENRNEQERNENEMRDRRDCQDSGVVCGFPKPEPHCCSGWCLFVCA
What are the official names of this protein?
Conotoxin Qc6.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLK4_NEMVE
Sequence: MTTQYMGDSIEDFQVLDLLGKGGFACVYRGRCLATGQEVAIKMIDKKAMRTAGMVNRVCNEVEIHCRLKHPSILELYTYFEDDNYVYLVLELAENGEANRYLRKQGHTLKESEVRRIMLQVVKGVLYLHSHGIIHRDLSLGNILLSSDMDAKIADFGLATRLSLPDEKHYTMCGTPNYISPEIATRDPHGLESDVWSIGCMLFTLLVGKPPFDTEAVRSTLNKVVLAEYDIPNHVSIEARDLISKLLKKNPQDRLTLSGILDHPFITNQTLNTKYSSPTRQHLNPRAYENSLDSGTGTMATISTGHAPFQQDNRHAVKSSSAERTSDIWPRDPKHPPSPPVRQRPSSCPSTENVTTGSSSHVRGSDVAQPAQYSGLKTRTSDSWLSDIHSSKIPKLPQKPLVGLDKMNGIQSKFKSYNATKYSSYYGSTLGDILHLAGQQNGTNTSSSGFYSADTKSYSANHGLKTSSTDHNNKESCQTRDNHMYEKSIEQPSATKSEHSRAYSSQDSRPHSHHKRHGSDSVSKDFDASPQPSQGESRRRQNHRSDSERQTRRAEKSRSGGRDKSLGELTEPLNAERLRPIRQKTRNAVVSITDEAEVCLEFLQQKGGQSIVTEVIRIASNGMKISVYQPSEAEKVLGSEPPLPPSAGNGSYLFPSLPSKYWKKYKYAAKFVQLVRKLTPKVTLYSKHAKCVLMENYPHADFEVCFYNGAKVHQSQECTRIIEPGGVSYTLESVGGIEGVPVEMRKLIQHVKAAYQQCVRLERIIMQEEKESNGNQYFPFIVGRRPPAWKNSSGKSEKQDQQGCSNGQSQPVLPSSPSIAAPAMTSLLSFDGTIASTAQTTNPAFPGKSRKTSPSKTSRHKQSPAQPIPAEVANAKTDPSPHHYVEGSSPIPSAHVCKMAFVDGVGWSSQLTTGEVWIQYTDGSQIIFHAAAAAIKFTDSTGNVTRYGYADRLPSVIKEKLSHLPAVIKTLATTSKVS
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the mother centriole cylinder, leading to the recruitment of centriole biogenesis proteins.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: RUVA_NITSB
Sequence: MIVGLVGEVLKKEPTYLHIEVGGVVYEVFISLNASAAIDKKQIRLHTTHIIREDSESLYGFVDINEKKMFDRLIKLNGVGPKVAIAICSTFKPQEFVQIVQQKNVAMLKKVPGIGPKSAQRILVELGEFDISESNVTSSAFQEASMALQSLGFKKEQIQKALQECTATDTASLVKEALKKIQKL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: USTR_ASPFN
Sequence: MSGAQRRKTGCWTCRLRRKKCNEDGQPCSNCEARGVFCHGYGPKPSWKDRGEREREEAQRLQLISRARTRRARATPTNSINGEPRRPSIDMNTSDMGSPIQMGLGSSDSSIFETSSLDLLDIPELGSSLWEPTLDIIQVQPPPSDAPSALQFPSILGDGLEEKEIDLIMYYVVEVFPRQHSSYQGTSVMERSWLLCVLKRSSSFYYTSLSLSAHYRLMSMPEGGQGRTALLQEYERYKTCSLFRFQELVSSATRPQSPISTGVVGESVICGVQIAMLEAVSKNMQSSYLHLSSAALSLAQLLDNTSTLDSSSISTNTTPPSSVLTTDLYHAGSMEYKALRCFSIILIWNDILHCSAQQTIPAAAKTYQKLLADESFIPLFADIVGCEGWVLVPILEAMLLASWKKDQEAKGQLSIRELLTKVDHIESILGDRMKRLAPAVLRQKEAGISSQSPEQIRLVHTYIFAHASFVHLHTVVSGAQPSVPEIRQSIDKSLAAWQLLPPSLINFKTMAWPFCVCGSMAVGSQRELFQKIMSENFQNQSTSSNLHCLKSVVEECWKNFDKRVPEQSPSSYNWKVVMEKLNLSILFI
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of ustiloxin B, an antimitotic tetrapeptide (PubMed:24841822, PubMed:26703898).
What are the official names of this protein?
ustiloxin B cluster transcription factor ustR, Ustiloxin B biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_ALKOO
Sequence: MNYYSASISQLIEEFTKLPGIGRKTAQRLAFHVINMPIQDAHNLADAIVKAKENIKYCKVCTNLTDQEVCNICSDERRDPLLICVVEDPRDVVAMERTKEFKGYYHVLHGAISPLEGIGPEDIKIKELLVRLSAQSADEVIIATNPNIEGEATAMYLSKLLKPMGIKVSRIAHGIPVGGDLEYADEVTLTKALEGRREI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: CEMA_SACOF
Sequence: MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSETFLTDIQEKRILEGFIELEELFLLDEMIKEKPKTHVQKLPIGIHKEIIQLAKIDNEDHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSIKAFFILLVTDFFVGFHSTRGWELLIRWVYNNLGWAPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PGK_SHIF8
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYLM_YEAST
Sequence: MLSRPSSRFLSTKRGPGPAVKKLIAIGEKWKQKTTRGLPKQDTLNSGSKYILCQFPYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQSMLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQGRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQLKDWPSNVKQMQKNWIGESVGAELVFKVADPKFENLIVFTTRPETLFAVQYVALALDHPIVQKYCEEMPDLKEFIQKSDQLPNDTKEGFQLPNIKAVNPLTKEEVPIFAAPYVVSSYGSAPSAVMGCPGHDNRDFEFWQTNCPGEHIKTCIAPFFDDASKVTEQERQRIIDTVPFTSTDGVLTKECGEHSGVLTVVARKSIMGMLNSEGLSKSVVRYKIRDWLISRQRYWGTPIPIIHCDNCGPVPVPESDLPVKLPELEGLDTKGNPLSTIDEFVNVACPSCGSPAKRETDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASKNMPVDIYIGGVEHAILHLLYSRFIAKFLGSINAWSDPAGIFEPFKKLVTQGMVQGKTYVDPDSGKFLKPDELTFVNDSPDGNTVIIKSNGKVPVVSYEKMSKSKYNGADPNECILRHGPDATRAHILFQSPIADALNWDESKIVGIERWLQKVLHLTKNILSLEKDLAISKDYKTPTDLNDAEVKFHNDFQRFLKSITESFEVNLSLNTVISDYMKLTNILESALKKGEVRNEMIVQNLQKLVTVIYPAVPSISEEAAEMINSQMEWNQYRWPEVERTTESKFKKFQIVVNGRVKFMYTADKNFLKLGRDAVIETLMNLPEGRMYLMNKKIKKFVMKFNVISFLFHK
What is the function of this protein?
Catalyzes the attachment of leucine to tRNA(Leu) in the mitochondrion.
What are the official names of this protein?
Leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: EAA5_HUMAN
Sequence: MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRMLKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFARDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEELPAASLNHCTIQISELETNV
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate.  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:9108121).  Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals.  Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina (By similarity).
What are the official names of this protein?
Excitatory amino acid transporter 5, Retinal glutamate transporter, Solute carrier family 1 member 7.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A7 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.