PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_STRGG
Sequence: MAELFYDDDADLSIIQGRKVAVLGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQGLRVVTPSEAAAEADVIMILVPDPIQAQVYEESVKDNLKDGDALFFGHGLNIRFGFIKPPAGVDVCMVAPKGPGHLVRRQYEEGRGVPCIVAVEQDASGKGLELALSYAKGIGGTRAGVIKTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMYEGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAKNWMAEYHNGLPKYNEYKKADSDHLLETTGRELRKLMSWVNDEEA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NSL1_ARATH
Sequence: MAFNNFTRLDAHSAAEKAVSVIGLGYDLCSDVRFSACKTTPDGSRLVEIDPTRNRDLIFPGGIVVNNVSSSIKCDKGERTRLRSDILSFNQMSEKFNQDMCLSGKIPSGMFNNMFAFSKCWPKDASSVKTLAYDGWFISLYSVEIVRKQLTLRDEVKREVPSSWDSAALAGFIEKYGTHVVVGVTMGGKDVIHVKQMRKSNHEPEEIQKMLKHWGDERFCVDPVESKSPASVYSGKPKEENLLQWGLQPFGTSVSSAVVMHTKNEEIMRVCIRRGGVDLGQSHERWLSTVSQAPNVISMCFVPITSLLSGLPGTGFLSHAVNLYLRYKPPIEELHQFLEFQLPRQWAPVYGDLPLGLRRSKQSSPSLQFSLMGPKLYVNTSKVDSGERPVTGLRFFLEGKKGNHLAIHLQHLSACPPSLHLSHDDTYEPIEEPVEKGYYVPVKWGIFSHVCTYPVQYNGARSDDTASIVTKAWLEVKGMGMRKVLFLRLGFSLDASAVTRKSCWDNLSTNSRKSGVFSMISTRLSTGLSPNPATTKPQSKIDINSAVYPRGPSPPVKPKLLSLVDTKEVMRGPEEQPGYWVVTGAKLCVEAGKISIKAKYSLLTVISEDSLV
What is the function of this protein?
Negatively controls the salicylic acid (SA)-mediated pathway of programmed cell death in plant immunity.
What are the official names of this protein?
MACPF domain-containing protein NSL1, Protein NECROTIC SPOTTED LESIONS 1, Protein NSL1.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 (TC 1.C.39) family.
Protein: TPM1_COTJA
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEERSKQLEDELVALQKKLKGTEDELDKYSESLKDAQEKLELADKKATDAESEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAQKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: PDXY_ACTSZ
Sequence: MKNVLSIQSHVVFGYAGNKSSTFPMQLSGIDVWALNTVQFSNHTQYGKWTGMVVPHQQIPEIADGIDAIGELKNCDAVLSGYIGSADQVAEIVKVSHLVKTRNAAALYLCDPVMGSAEKGCVVADGVREGLIDIALPQADIITPNLLELRELSGLRAENFEQAVIAAQHLLTKGPKTVIVKHLGSAGKYPGKFDMLLANREGVWCLSRPLYPFAKDPVGVGDLIAGLFLANLLNGKSEPEAFELTGNAVNDVMEITHKLNSYELQLIEARHAIMAPQNRYKAEKIA
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: F16PC_STAAB
Sequence: MTQITERELKKKYLDLLSQRFDTPEKLATEIINLESILELPKGTEHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKDKLSTKELNDLTALVYYPEDKLQLIKCDFQNYGQLNVWYITTIEHLIQLIKYCSSKYTRSKLRRALPEQYVFIVEELLYKNNEFKNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIVEDAYGINLRPLLTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPVIKRRPNFEMDERLVLEKVNYDTNEITVYRKTYPLKDTCFQTVNRDNPAELLPEEEEVMNKLLLSFQQSEKLRRHMSFLMRKGSLYLPCNGNLLIHGCIPVDENGEMESFEIDGQTYSGQELLDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHKEEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIEELSIKRIVDKELQRKKIRNTNKGKELQAQIDILKMLMHDRYLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: RL15_HELPJ
Sequence: MGLENLKPAKGSVKKIKRVGRGQGSGMGKTATRGGKGQTARTGYKAKRGFEGGQQPLQRRLPKIGFRTKDSHIYSINVEKNEAIKSLEEITFSSLRALHHFPLYIEGVKLIGKDAKNLASKIKDERIKTSGQK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SDP1_YEAST
Sequence: MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLDVRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTNVQANSYRKVP
What is the function of this protein?
Mediates dephosphorylation of MAPK substrates such as SLT2, acquiring enhanced catalytic activity under oxidative conditions.
What are the official names of this protein?
Dual-specificity protein phosphatase SDP1, Stress-inducible MAPK phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: PX113_ORYSJ
Sequence: MAAAAAAAGSSDSRKPAAHPPPRDFLVHVEAYLSRRDGVDKLLKISRYAARLALAAGPLPPAASARLKSFESSVGLSRKAFRLGKFVQNVNALRAHPHPPPAVALLAYGGEGVYYFLEQFVWLAKAGLLPAHLLPRLQRLSAWAELLGYVGSITIKLEEIGKLESSVKMRLKEGCREESDVVRTLRVKLLLKRMSVVQDVADAVMALGDVTDGKGLLGSSTLMASAGLLSALISAHKNWNSC
What is the function of this protein?
Involved in peroxisomal proliferation.
What are the official names of this protein?
Peroxisomal membrane protein 11-3, OsPEX11-3, Peroxin-11-3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: PLYC_BACSU
Sequence: MKKIVSILFMFGLVMGFSQFQPSTVFAADKVVHETIIVPKNTTYDGKGQRFVAGKELGDGSQSENQDPVFRVEDGATLKNVVLGAPAADGVHTYGNVNIQNVKWEDVGEDALTVKKEGKVTIDGGSAQKASDKIFQINKASTFTVKNFTADNGGKFIRQLGGSTFHVDVIIDKCTITNMKEAIFRTDSKTSTVRMTNTRYSNVGQKWIGVQHIYENNNTQF
What is the function of this protein?
Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action.  In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.  Is also able to cleave trigalacturonate to galacturonic acid and unsaturated digalacturonate.
What are the official names of this protein?
Pectate lyase C, Pectin lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PARP_SACSO
Sequence: DINGGGATLPQKLYQTSGVLTAGFAPYIGVGSGNGKAAFLTNDYTKLTATELSTYATNLQPTWGKLIQVPSVATSVAIPFRITDWSGISGAGRTGPITVVYRITYMSPDFAASTLAGLDDATKGVSPAPSNVSDAIAQVLPPNDPSAPLDVTNPDDGVAGVQPYPDSGYPILGFTNLIFSAFFTKAFFTKHFGDTNNNDDAITANRFVPLPDNWKTELSTYATNLQPTWGK
What is the function of this protein?
Catalyzes auto- and hetero-ADP ribosylation and produces short oligomers by elongating the ADP-ribose chain (up to 6-mer).  Binds DNA non-specifically but with high affinity.  Forms very stable complexes with circular DNA wherein the circular DNA confers thermostability compared to linear DNA.
What are the official names of this protein?
NAD(+) ADP-ribosyltransferase, PARPSss, Poly(ADP-ribose) polymerase-like thermozyme.
Protein: ABRB_BACSU
Sequence: MFMKSTGIVRKVDELGRVVIPIELRRTLGIAEKDALEIYVDDEKIILKKYKPNMTCQVTGEVSDDNLKLAGGKLVLSKEGAEQIISEIQNQLQNLK
What is the function of this protein?
Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation.  It controls the expression of genes spovG and tycA.  AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.
What are the official names of this protein?
Transition state regulatory protein AbrB.
What is the protein family that this protein belongs to?
To B.subtilis Abh and SpoVT.
Protein: ISAA_STAHJ
Sequence: MKKTVIASSLAVALGVTGYALTTDNSAHASESTTNYAQLANLAQNNPSELNAHPVQAGAYNITFVKDGFKYNFTSDGQSWSWNYTYVGGADTVATTQAAPAAQSTDYSASYSNEASTQSVSSNQQSSNTNVEAVSAPKTTSYSASTSSSSSASTGGSVKEQFLANGGTEAAWNAIVMPESGGNPNAVNPAGYRGLGQTKESWGTGSVASQTKGMINYANSRYGSLDAAIAFRDNHGWW
What is the function of this protein?
Is able to cleave peptidoglycan.
What are the official names of this protein?
Probable transglycosylase IsaA, Immunodominant staphylococcal antigen A.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. IsaA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KLH25_XENTR
Sequence: MSVTVHENRKSRTSTGSMNISLYHKLSHSDCVLNHLNTMRKQRLFTDVTLWAGNRSFPCHRAVLAACSQYFEAMFSNGLRESLDNTVNFHDSLHPEVLELLLDFAYSSKIIINEENAESLLEAGDMLQFHDIRDAACEFLEKNLYPSNCLGMMILSDAHQCQRLYELSLRTCLSNFATLHNTEDFCSLSKDMVLDLISSDELEIEDEQVVFNSVLHWVKEDLDKRKDYFPELLRKVRLALLPSELLKEAVVCEDLIIADERSKLIMDEAVVCKKKILQNDGVVTSLCAKPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSACAIGCKVYVTGGRGSENGVSKDVWVYDTINEEWSKSAPMLIARFGHGSAELENCLYVVGGHTAVAGVFPASPSVSLKQVEKYDPLTNKWTMMAPLRDGVSNAAVVSAKLKLFAFGGTSIHRDRVSKVQCYDPDENRWSIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALASGNKVYVVGGYFGTQRCKTLDCYDPTSDSWNSITSVPYSLIPTAFVSTWKHLPA
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex involved in various processes, such as translation homeostasis and lipid synthesis.  The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated eif4ebp1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low.  The BCR(KLHL25) complex also acts as a regulator of lipid synthesis by mediating ubiquitination and degradation of ACLY, thereby inhibiting lipid synthesis.
What are the official names of this protein?
Kelch-like protein 25.
Protein: RS12_THEAB
Sequence: MPTINQLVRHGRKVIKEKSKSPALQGHPQKRGVCVRVSTMTPKKPNSALRKIARVRLSNGIEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGIRYKIIRGALDAAGVENRKQSRSKYGAKRPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HNRDL_RAT
Sequence: MTGTARSALPLPQSPARALRPSGAARAAPSLSPSRFSACPLDPSSFPTSGNKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGDESYSGYGGYDYTGYNYGSYGYGQGYTDYSGQQSTYGKASRGGGNHQNNYQPY
What is the function of this protein?
Acts as a transcriptional regulator.  Promotes transcription repression.  Promotes transcription activation in differentiated myotubes.  Binds to double- and single-stranded DNA sequences.  Binds to the transcription suppressor CATR sequence of the COX5B promoter.  Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs.  Binds both to nuclear and cytoplasmic poly(A) mRNAs.  Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers.  Binds to the 5'-ACUAGC-3' RNA consensus sequence (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein D-like, hnRNP D-like, hnRNP DL.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner.
Protein: CSPL4_SELML
Sequence: MGAYDGAEAPRAAPASTAANSRPSRLLLLHSLLLRLVAVVLSILVIAVMVHAKQRVMIFKAEWDNSKAFVALVTISAICLGYSFLQFILSAFHLCSKSWKSPTKCWAWMNFIADQILTYAMLGAAAAAAELAYIAKNGSSRAQWQPICSTFNTFCTRAGASIILSFIAVLALANSSAISAYHLFRRPSSSV
What are the official names of this protein?
CASP-like protein 2U4, SmCASPL2U4.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S47A1_DANRE
Sequence: MDSITSYNVTQMNGDTKQEKCDDVLSTSSTQKFCGGCRKKLRSLLPVNYKTEIVELLKLAGPVFISQLMIFLISFVSTVFCGHLGKTELAGVALAIAVINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTISQYSLAVFLYVYIRWKNLHKATWDGWSRDCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLFFIILIYKLDWKKATQEALIRAGVQLTETKDESFGLENKGCTEEAAKESQITEEGLTDANTDLEGLSKGGEGISEAGAKTTVGAVLTTKQLIVRRGLAVLLMVLILAGGIVLNEMLVRYLR
What is the function of this protein?
Solute transporter for tetraethylammonium (TEA), cimetidine, metformin, guanidine, N-methylnicotinamide (NMN) and also the zwitterionic cephalosporin cephalexin.  Responsible for the secretion of cationic drugs across the brush border membranes (By similarity).
What are the official names of this protein?
Multidrug and toxin extrusion protein 1, MATE-1, Solute carrier family 47 member 1.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ITPI2_MOUSE
Sequence: MNRPLSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTETTTQDEDEDDEEDLPGTKLPAPAGRGNVPNEKIAIWLKDCRTPLGASLDEQSSGTPKGVLVRNGGSFEDDLSLGAEANHLHEPDAQVENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSTKEVADSPPPLTRSNTANRLMKTLSKLNLCVDKTEKGEGGSSPATEKGRTLSISLSEDGGGGKSDPKLQKVVKKKESSSMLATVTEEVSGSSSTVTDSVDADRLSEEADSTISHQEESEESREAHSQEKDPLRKSAVTDPDLGHDGRVSSHCELESSSELKSAQASSSEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATCQLSLAKSKRDHLLRTASQHSDSSGFAEDSTDCVSLNHLLVNESLQAMGSSADSCDSETTVTSLGEDHVTPTAQDQPYFNESEEESLAPLQKGRAKVEIVAEKRKADNQDFPQCVTAENAGNNESTKGPCEPGHQITETGEHPPLAATGELPREESVESDVEKGSECEFAQYTTHHILRSLASFEAQGSGMSSEKKTGFPSSVDRVNTALQRAQMKVCSMSGQRVGRSLIKSKDLLKQRYLLAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQDLEKQGTEHDGQSLVKSTIFIPPPSVKKEEAPQSEGTRLEECHHGRLAPCPQFAPISQSTCSLHSVHSEWQDRPLCEHMRTLSAHSVPNISGAACSAFSPFGCPYSHRHAAHPYRACSVNPPSAIEMQLRRVLHDIRSSLQNLSQYPMTRGPDLAAAPYSTQNSSVLPLYENTFQELQVVRRSLNLFRTQMMDLELAMLRQQTVVYPHMTEEDRYEVDQLQGLRNSVRMELQDLEMQLEERLLGLDEQLRAVRVPSPFRPSALPGMCGSRSVDNLSCPSPLNVMEPVTELIREQSYLKSELGLGLGDMAYEIPPGESSESVFSQATSESSSVCSSPSHTNRRSRGLPGSKPRARLVARKKIFRASVALTPTAPSRTGSVQTPPDLESSEEAGGAEEASPVVGLASHVEEEPEDLSLMPAAEEMHRNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKAPGPKQDSH
What are the official names of this protein?
Protein ITPRID2, ITPR-interacting domain-containing protein 2, Ki-ras-induced actin-interacting protein, Sperm-specific antigen 2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Note=Located near the plasma membrane. Associated with actin filaments. May also exist as a membrane-bound form with extracellular regions (By similarity).
Protein: RS3_NAUPA
Sequence: MGQKTNPIGLRLGINKNWRSRWFINYNTMPENVLGDYELRKFLKKKLYYAGISDIIIERTAKKIRITIFAAKPGIIIGKGGSEIEALKAELQKRIGNKELILNIKEERKPQLSAQLAAENVATQIERRVAFRRAMKKVIQSALKSGAKGIKVQVAGRLNGAEMARTEWYLEGRVPLHTLRAKIDYGFAEALTTYGIIGVKVWIFKGEVLQRKMNSDDTATPERKAPRRRKGRRNVNAKKN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: F16PC_LISIN
Sequence: MENIDMKYLHLLAKQYPTIAKTATEIINLEAIMNLPKGTEHFLSDVHGEYSAFEQVLRNGSGVVKRKIRDIFGDELDDAEINSLSTLIYYPEEKMDLIAEEMDDMHDWYRTTLFRLIELCQYVASKYTRSKVRKAMPEDFAYILEELLHENYNEEDKKMYYEEILQHIISLDRAAEFISALSRLIQQLVVDHLHIVGDVYDRGPYPDKIMDTLMNYHSLDFQWGNHDILWMGAASGSRVCAANVIRISARYLNLDILEDSYGISLRPLALFADEIYKNDPCTYFQPKNEDNLNYSKAEITQIARMHKAISIIQFKLEGEIINRRKEFDMNHRLLLQMIDYKKGTIHLKGKDYQLLDTHFPTIDPNDPYKLTKEEKELIEKITASFKNCRRLQKHVQFLYSKGSMFLTYNGNLLYHGCIPLYEDGTFMEMKLRGENFSGRELLEQFEILTREAYVRKPGTKEKKYACDIVWYLWTGAVSSLFGKSEMTTFERYFIAEKETHKEEKNPYYKLRNEETICKQILEEFGLDGECGHIINGHTPVKEGKGESPIKANTKMLVIDGGFAKAYHKETTLAGYTLLYNSYGLQLVSHQPFTTKEDAIKNETDILSTRQVIEMEINRKRVRDTDIGKNLNEQATDLKMLLEAYRNGSLHENS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: MURG_LATSS
Sequence: MISGGGTGGHIYPALALIERLKQRGLLDAVLYVGTERGLESKIVPDQGIDFKTLEIQGFKRSMNLNGIKTNLKTIELFMSSIKSAKKMIKEFKPDVVIGTGGYVSGSLLYAASRLKVPTIIHEQNSAAGVTNKFLARFVDKVAISFESVSDQFPMHKVVLTGNPRAQQVAGMVPNERLSEFGLKTDSPTVMIFGGSRGAPSINKAFIDAVPLLNERDYQVLFVSGQVHYENVQAALANTTLNSNLAFVPYISNMPEVLPDLKAIVGRAGATSLAEITALGIPSILIPSPYVTNDHQTKNAQSLVKEDAAMLIPEPELTGASLVKALDTLFETPEKQHAMAKAAKKSGIRDASDRIIEVIETII
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1349_STRPC
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQKVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein MGAS9429_Spy1349.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: COBQ_MYCSS
Sequence: MTGGALLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGGEIGRAQAMQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADELASLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTVAVLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVSVVAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADVVVLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHIDDAVESRAGRVDGLGLLDADIAFAAEKTLRHRTTPLQGYEIHHGQVTRCAADDWAGIGVRRDAVYGTHWHGLFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDLDAALGLVDAGPPPRPTISTGIT
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RL10_MAIZE
Sequence: MGRRPARCYRQIKNKPCPKSRYCRGVPDPKIRIYDVGMKRKGVDEFPYCVHLVSWERENVSSEALEAARIVCNKYMTKSAGKDAFHLRVRVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTCARVDIGQVLLSVRCKDNNAAHASEALRRAKFKFPARQKIIESRKWGFTKFSRADYLKYKSEGRIVPDGVNAKLLANHGRLEKRAPGKAFLDAVA
What are the official names of this protein?
60S ribosomal protein L10, QM protein homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: F223B_HUMAN
Sequence: MYVQEHRLWGLMDKPHSAPCLMSLSLSFLICNKGRNAIRVQQSTDERMDAMLLRQCPTQGTRKNHESNSSLHHVPNWIFHSTIIPPNKGSKRCLRKVDWLLPRAGGVGGKRGVTADGDRVSF
What are the official names of this protein?
Protein FAM223B.
What is the protein family that this protein belongs to?
Belongs to the FAM223 family.
Protein: PPB1_HUMAN
Sequence: MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP
What is the function of this protein?
Alkaline phosphatase that can hydrolyze various phosphate compounds.
What are the official names of this protein?
Alkaline phosphatase, placental type, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GREA_RHOPA
Sequence: MVEKIPMTASGYAALSDELKHRQSVDRPRIIEHIAEARSHGDLSENAEYHAAKEEQSHNEGRINELEDKLARADIIDVSKLSGDTVKFGATVTLIDEDTEKKAVWQIVGEAEADAKKGKISITSPLARALIGKKAGSSVEVVAPGGAKAYEIAKVEWR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RL6_RALPJ
Sequence: MSRVGKAPIALPKGAEVNFAGGLLTVKGPLGTLTQPIHSLVKVNTDNGTITFAPADESREANALQGTMRALTANMVKGVTTGFERKLNLVGVGYRASVQGTALKLQLGFSHDVIHEMPEGVKAETPTQTEIIIKGSDKQKVGQVAAEVRGYRPPEPYKGKGVRYADERVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.