PharMolix/UniProtQA huggingface dataset:
Protein: PPOA_ASPFU
Sequence: MSEKQTGSANGGLGKTLAQLEQVVSASLRPLPSQTGDGTYVTEQVKTGILKDLSHVDLGDLKTLVDVSKSALTGEALDDRKYIMERVIQLSAGLPSTSQIGKELTNTFLTTLWNDLEHPPISYLGRDAMYRRADGSGNNVLWPHIGAAGTPYARSVQPKTVQSPNLPDPETLFDCLLARKEYKEHPNKISSVLFYIASIIIHDLFETDRKDPAISLTSSYLDLSPLYGNNQQEQDLIRTFKDGKLKPDCFSTKRVLGFPPDVGVVLIMFNRFHNYVVEKLAMINEGGRFTKPQESDTAAYAKYDNDLFQTGRLVTCGLYVNIILKDYVRTILNINRTDSIWSLDPRSEMKDGLLGRAAAQATGNQVAAEFNLVYRWHSCISQRDQKWTEDMYQELFPGQDPSKISLQDFLRGLGRWEAKLPGEPRERPFAGLQRKADGSYDDNDLVKIFEESVEDCAGAFGALHVPTVFRSIEALGIQQARSWNLATLNEFRKYFNLAPYKTFEEINSDPYVADQLKRLYDHPDRVEIYPGIIVEDAKESMAPGSGLCTNFTISRAILSDAVALVRGDRFHTVDFTPKHLTNWAYNEIQPQDSVDQTHVFYKLVLRAFPNHFRGDSIYAHFPLVVPSENKKILTKLGTADKYSWDRPNYTPPPQFINSHSACMSILSDQETFKVTWGSKIEFLMRHNNQPYGRDFMLSGDRTPNAMSRQMMGKALYRDKWETEVKRFYENITLKLLHRYSYKLAGVNQVDVVRDIANLAQVHFCASVFSLPLKTESNPRGIFTESELYQIMAVVFTSIFYDADIGKSFELNQAARAVTQQLGQLTLANVELIAKTGFIANLVNSLHRHDVLSEYGVHMIQRLLDSGMPAPEIVWTHVLPTAGGMVANQAQLFSQSLDYYLSEEGSVHLPEINRLAKEDTTEADDLLLRYFMEGARIRSSVALPRVVAQPTVVEDNGQKITLKQGQHIICNLVSASMDPVTFPEPDKVKLDRDMNLYAHFGFGPHQCLGLGLCKTALTTMLKVIGRLDNLRRAPGGQGKLKKLSGPGGIAMYMTPDQTAFFPFPTTMKIQWDGDLPEVKE
What is the function of this protein?
Bifunctional heme-containing enzyme that oxidizes linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (within the N-terminal heme peroxidase domain), which is subsequently isomerized to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (within the C-terminal P450 heme thiolate domain).  Oxidized unsaturated fatty acids, so-called oxylipins, derived from endogenous fatty acids, influence the development of the asexual conidiophores and sexual cleistothecia and regulate the secondary metabolism.  These substances were collectively named psi factors and are primarily a mixture of hydroxylated oleic, linoleic and alpha-linolenic acids.  They are termed psi-beta, psi-alpha, and psi-gamma, respectively.  Oxylipins may also serve as activators of mammalian immune responses contributing to enhanced resistance to opportunistic fungi and as factors that modulate fungal development contributing to resistance to host defenses.
What are the official names of this protein?
Psi-producing oxygenase A, Fatty acid oxygenase ppoA.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
Protein: ILVB_PORUM
Sequence: MLSKQIIGSEKTGRFALLDSIVRHGVIHIFGYPGGAILPIYDELYAWEELSLIKNILVRHEQGASHAADAYSRSTGKVGVCFATSGPGATNLVSGIATAHIDSVPILAITGQVGRPFIGTDAFQEVDIFGITLPIVKHSYVVRDPRDMSRIVAEAFYICKHGRPGPVLIDVPKDVGLEKFNYFSVEPGQVKIPGCRPLSNLKSRQILMAAKMIQQSSQPLLYIGGGAIISDAHSIIKELVDLYKIPVTTTLMGKGIFNEDSEFCLGMLGMHGTAYANFAVSECDLLIALGARFDDRVTGKLDEFACNAQVIHVDIDPAEVGKNRIPQVAIVGDVTEVVTSLLNLLKNNFKPYPEQIISWQERIHRWRQQYPLLVPKKSTSISPQEILVTTNQLAQDAYFTTDVGQHQMWSAQFLKVKSKHWISSAGLGTMGYGLPAAIGAQVAHPNELVICVSGDSSFQMNMQELGTIAQYKLPIKIVIINNRWQGMVRQWQQAFYGERYSHSRMTEGAPNFQKLAEAFGIKAFTVNNRQNMESSLKDAMKYPGPVLLDCQVTENENCYPMVAPGKSNAQMIGIAKPQRGTASNYVSRNI
What are the official names of this protein?
Acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CARA_STRAW
Sequence: MTTSTRGAAKVPAVLVLEDGRTFRGRAYGAVGVTFGEAVFSTGMTGYQETLTDPSYHRQVVVMTAPHVGNTGVNDEDPESKRIWVSGYVVRDPARVPSNWRSRRSLDEELRHQGVVGISGIDTRALTRHLRESGAMRVGIFSGSALPDEGTMLAEVRQAPEMKGANLAAEVATKETYVVPAIGAKRFTVAAVDLGIKGMTPHRMAERGIEVHVLPATATAEDVYAVNPDGVFFSNGPGDPATADGPVAVMREVLARKTPLFGICFGNQILGRALGFGTYKLKYGHRGINQPVQDRTTGKVEVTAHNHGFAVDAPLDQVSDTPYGRAEVSHVCLNDNVVEGLQLLDQPAFSVQYHPEAAAGPHDAAYLFDRFVSLMEGQRA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: URK_YERPA
Sequence: MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQALKAGKPVELPLYSYTEHTRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_HALSA
Sequence: MVTNTSGKKKTAVARATVSDGEGRVRINSQPVELVEPEMARLKMLEPFRISGSDLRGDVDIDIDVAGGGFAGQADAVRTAIARGLVEHYGDAELRDAFREFDRSLLVNDVRQRESKKWGGPGARARYQKSYR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TKN2_UPERU
Sequence: QADPKTFYGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Rugosauperolein-2, Rugosauperolein II, [Lys5,Thr6]-physalaemin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IROK_ECOLI
Sequence: MKPALRDFIAIVQERLASVTA
What is the function of this protein?
Possible increased expression of this protein (due to mutations upstream of the start codon) is proposed to be responsible for resistance to 3-hydroxypropionic acid (3-HP).
What are the official names of this protein?
Protein IroK, 3-hydroxypropionic acid resistance peptide.
Protein: DEF_LIMRJ
Sequence: MYLMKDITRDGNPVLRKRAAKVSFPLSDEDQKLAKDMMKYLEVSQDPELCKKYKLRAGVGLAAPQVGVSKQMAAVLVPAPDEDEKPLFKDVIINPVIVSESVQYGALTEGEGCLSVDKDVPGYVPRHDRITLRYQDVNGETHKVRLKHYPAIVCQHEIDHLHGVLFYDHINKDQPFEAPADTVMIS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: 3MGH_BACCQ
Sequence: MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: MATK_ZYGCR
Sequence: MIGVKQTKRLYAYFLREDLYITLVQHTKNQIHATSQTNNFIVPISFFRIKKAITRMRKQHNITILKQGNLSDEYQAILQIINVALVYINKPVFSLYVPSFRNQTYPKQFINNTITGLNQHHTNIYNGMFSKRDVSIHSAFLFLENRYHSCNYLLEDKIHYLIHPEIIIRIIRKYVFDVCLIHCYRIVFYFIMMHLNRSKQTFNYSMDQAILSMRNIYAIEIDSFFADESLKILNQTTYSPIWAPYDRSIFHKCTLYEFHVTFKSVLNRKILKHIIYYSKLSKNKYGLSPIGFYRFGACHYLRCNSIWKFAMQANSNFMYLFGFRYMRFITRRMGAFYFHYVSSVVYDIRSITKHKIVLLGVLVKSDNAVVKIQTQIFQNILPITYLRIQYIRILSPNHLVIKALYKYQLCTSAGYPLHRYSWTTFGNIQIVQRFKVLQHSIIFYYSGCINRKALSYVKQILRYSCAKTLAFKHKTTTRNILSTKIDQNVNILNVFNTKKQFWLSFELNNITLNLRVWHLELFNQYRLMQDD
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns (By similarity).
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTBB3_METAC
Sequence: MATEYALRMGDGKRIYLTKEKILSEIEAGSSNAADLGDIPDLSTDEMKKLAEILMMPGKAVSVEQGMEVPVTHDIGTIRLDGDQGNSGVGIPSSRLVGCMTHERAFGADTMELGHIDYSFKPVKPVVSNECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDGPFENPGDLMKMFKIDKARESMEHAADHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLRAVEVLRAQFPEMYIEVGMAGEMVLGMHGELEYDEVRLAGLWPHEQAPLIAKAGANVFGPVVNTNTSKTSAWNLARAVTFIKEAVKASPIPCHVNMGMGVGGIPMLETPPVDAVTRASKAMVEVAGVDGIOIGVGDPLGMPISHIMASGMTGIRAAGDLVARMEFSKNMRIGEAKEYVAKKLNVDTMDLADEHVMRELREELDIGVITSVPGAAKGIAAKMNIEKLLGIKINSCETFRAQLA
What is the function of this protein?
Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
What are the official names of this protein?
Dimethylamine methyltransferase MtbB3, DMA methyltransferase 3, DMAMT 3, Dimethylamine--corrinoid protein methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the dimethylamine methyltransferase family.
Protein: RL40_HALS3
Sequence: MSETIEDRLLNKQVCMRCNARNPTDAESCRKCGYKNLRTKASERRSA
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: RL33_FINM2
Sequence: MRDKVILECTECKSRNYTTKKNKKLHPDRVETNKYCKFCKKHTLHKETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DCDA_BACSU
Sequence: MFLHGTSRQNQHGHLEIGGVDALYLAEKYGTPLYVYDVALIRERAKSFKQAFISAGLKAQVAYASKAFSSVAMIQLAEEEGLSLDVVSGGELYTAVAAGFPAERIHFHGNNKSREELRMALEHRIGCIVVDNFYEIALLEDLCKETGHSIDVLLRITPGVEAHTHDYITTGQEDSKFGFDLHNGQTERAIEQVLQSEHIQLLGVHCHIGSQIFDTAGFVLAAEKIFKKLDEWRDSYSFVSKVLNLGGGFGIRYTEDDEPLHATEYVEKIIEAVKENASRYGFDIPEIWIEPGRSLVGDAGTTLYTVGSQKEVPGVRQYVAVDGGMNDNIRPALYQAKYEAAAANRIGEAHDKTVSIAGKCCESGDMLIWDIDLPEVKEGDLLAVFCTGAYGYSMANNYNRIPRPAVVFVENGEAHLVVKRETYEDIVKLDLPFKTGVKQ
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: W_BPP21
Sequence: MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTAASLDELNRAINDAESVLGTTRCRRRPLGVRL
What is the function of this protein?
Plays a role in morphogenesis of the virion head after genome packaging.  Presumably interacts with the portal vertex to stabilize the packaged DNA within the head after packaging.  Probably binds to the head-tail connector protein gp8.
What are the official names of this protein?
Head completion protein gp3, Gene product 3, gp3, Head-stabilizing protein, Head-tail joining protein.
What is the protein family that this protein belongs to?
Belongs to the lambda phage gpW family.
What are the subcellular locations of this protein?
Virion. Note=Probably part of the head-tail connector.
Protein: SLAP1_HUMAN
Sequence: MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
What is the function of this protein?
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling.  Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells.  Involved in the negative regulation of positive selection and mitosis of T-cells.  May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
What are the official names of this protein?
Src-like-adapter, Src-like-adapter protein 1, SLAP-1, hSLAP.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Note=Colocalizes with endosomes.
Protein: FAN1_DICDI
Sequence: MKSNTKNSVKRKSPPPVNPNKKFPSFEGKQTSIKDFFFNDTTTPPKTPTQPIRFTQNNNKENDKSNNNNNNNNTITPIKKTTTTTTVVVESFDDSRNTNLIQQFQKASTPSSPQIPNKLPQQENQQQIPNTQQQQIKQLQQQQQQQQQESPNNLFKTIKTTTTTETFEEFLLSQPTTPPPSNTTTTTTTTSSSSPSSSNNITTIDDKNNLIKNNRYYLNDFLIVTETVYKRDKHLFINDEKDYIEGMIETLDRDSQHLFVRLYNRKGPWFQINELKSSNYQNEIKNIGAAIESLVEYGFLEYYSSDKHDYNEIANLLKIDQLKSIASSFSIPNSSGKETFLKVISGEPFKGQSTLFSPKPIYKKKVENLVGESIKIVTEVVELWRMIHHLYFYSWSTHDSKSMIVNNIMGIKYPEYTVWKSKVKKEVQQKEEEVEKEKEEILQNQLIQVKQESDVIDLTQNSSGSSNNNNNNNNNNNNNNNNNNNIKEYDIDLTENESIFPNRESLLKYENARKLEEKSINLYESGGDLVALESILQVCLDELGRSVSKKVKYSFALKFTVGWVYTRILSWSIDIFEKLRKYQQCIDFLMLLIESPYCRGKRGYWWQRMIINHKHLHRSDDALLIAERSLKEDPFLRSGDRLAIEKHLIQLSSPPRRWRIPAGLIQFSYKLKEPISTTIYREKVSNNQQGYKSKYLFLTPQIKINKIKKIIIKSSQSQNNQQKVQSSLSSQIQTQIQTQIQTQIQSSQIQIQSPIQSQSQSQNQTPIQSQINNNNNNILAISSQKSFDSILTTTSINNTQSSSQNIYIDEETSLEITSDDELFPPGQSYKIEKENQLQITNSVKKEEEQEEEEEEEEEGQGQEEEEEEEEIIEITHGTVEEVSLEHYSQNGGWEGIHCETSIFITLYVLYFWDIIFDSNVPHVFQSPFQNSPLDFGSDEFYFTRKEAIDNRIKRLEHSNYDDLLILLNQSWLHNGCEARGVNWKSTSLEQLSIISKCLGGKLIAFISRLLTEDFKSFSHGMPDLLLWKLNNNNDDDIDDKNNNNSSIKFVEVKGTGDRLRDQQRIWIDMLISFGCDVEVCLVKNKKN
What is the function of this protein?
Nuclease required for the repair of DNA interstrand cross-links (ICL).  Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
What are the official names of this protein?
Fanconi-associated nuclease 1 homolog, Protein MTMR15 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAN1 family.
Protein: SUCC_OPITP
Sequence: MNIHEYQAKALFEKFGVLVPKGAPAKTPEEFVTALAQLPEGMIVVKSQIHAGGRGKGTFTDGFKGGVKVCKSKAEAREAAGKMLGNTLVTAQTGPAGRKVQTIYFNVGSQIKKEYYLAILLDRATSRPVIVASTEGGMEIEKVAHDTPDRIFKVHVDPAYGLADFQVRELVFKLGFTAAEGKNASKLIRALYRCFWENDASMVEVNPLITTPDGQVEALDAKVAFDDNALFRHPELVELRDLNEEDPKEIEASKHELNYIALDGNIACLVNGAGLAMSTMDIIKHFGGTPANFLDVGGGASREQVVAAFKIILGDKNVRGILVNIFGGIMDCNVIAQGIVDAVKEVGLELPLVVRLEGNNVAAGKATLATSGLKLVSGDSMADAAQKIVKLVA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: KPYK_DROME
Sequence: MVNVTIYDEAPQLKPNEVPQNMAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDSLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAGTIDASHAAAIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: RL7_MESM1
Sequence: MAKLTKESFIQSLKEMNIKEVMELVNAMKEEFGIDPSAVVVAGGAAGGAEVAEKTEVTITLKNAGGNKVPVIKKVREISPELSLMDAKKLVDSAPAKLKDNVKPEEAEEIKAAFAALGAEISID
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL36_CERS4
Sequence: MKVANSLRSLKLRHRDCQVVRRKGRVYVINKTQKRYKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DDB2_MOUSE
Sequence: MAPKKCPETQKSPDVAVLLRSKSRRGPQELEPEAKKLRVQGPVSSRTCESCCLLAELSSLQIPSRSSSIVRDLYQHKLGKATWSSLQQGLQKSFLHSLASYQVFRKAAPFDRRTTSLAWHPTHPSTLAVGSKGGDIMIWNFGIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILRVYTSSNSCKVWFCSLDVSAKSRVVVTGDNMGHVILLSTDGKELWNLRMHKKKVAHVALNPCCDWLLATASIDQTVKIWDLRQIKGKDSFLYSLPHRHPVNAACFSPDGARLLTTDQNNEIRVYSASQWDSPLNLISHPHRHFQHLTPIKATWHSRHNLIVVGRYPDPNLKSCVPYELRTIDVFDGSSGKMMCQLYDPGYSGITSLNEFNPMGDTLASTMGYHILIWSQEEDGSQKDHERL
What is the function of this protein?
Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively (PubMed:12107171).  Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (PubMed:33937266).  The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches (By similarity).  Also functions as the substrate recognition module for the DCX (DDB2-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB2-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1) (By similarity).  The DDB2-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage (By similarity).  The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair (By similarity).  The DDB2-CUL4-ROC1 complex also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER (By similarity).  The DDB2-CUL4-ROC1 complex also ubiquitinates KAT7/HBO1 in response to DNA damage, leading to its degradation: recognizes KAT7/HBO1 following phosphorylation by ATR (By similarity).
What are the official names of this protein?
DNA damage-binding protein 2, Damage-specific DNA-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Accumulates at sites of DNA damage following UV irradiation.
Protein: PMA2_SCHPO
Sequence: MQRNNGEGRPEGMHRISRFLHGNPFKNNASPQDDSTTRTEVYEEGGVEDSAVDYDNASGNAAPRLTAAPNTHAQQANLQSGNTSITHETQSTSRGQEATTSPSLSASHEKPARPQTGEGSDNEDEDEDIDALIEDLYSQDQEEEQVEEEESPGPAGAAKVVPEELLETDPKYGLTESEVEERKKKYGLNQMKEEKTNNIKKFLSFFVGPIQFVMELAAALAAGLRDWVDFGVICALLLLNATVGFVQEYQAGSIVDELKKTMALKASVLRDGRVKEIEASEIVPGDILHLDEGTICPADGRLITKDCFLQVDQSAITGESLAVDKHQNDTMYSSSTVKRGEAFMVVTATADSTFVGRAASLVGAAGQSQGHFTEVLNGIGTILLVLVILTLLCIYTAAFYRSVRLAALLEYTLAITIIGVPVGLPAVVTTTMAVGAAYLAKKKAIVQKLSAIESLAGVEILCSDKTGTLTKNRLSLGEPYCVEGVSPDDLMLTACLASSRKKKGLDAIDKAFLKALRNYPKAKDQLSKYKVLDFHPFDPVSKKITAYVEAPDGQRITCVKGAPLWVFKTVQDDHEVPEAITDAYREQVNDMASRGFRSLGVARKADGKQWEILGIMPCSDPPRHDTARTIHEAIGLGLRIKMLTGDAVGIAKETARQLGMGTNVYNAERLGLSGGGDMPGSEVNDFVEAADGFAEVFPQHKYAVVDILQQRGYLVAMTGDGVNDAPSLKKADAGIAVEGASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYAYVVYRIALSLHLEIFLGLWLIIRNQLLNLELIVFIAIFADVATLAIAYDNAPYAMKPVKWNLPRLWGLATIVGILLAIGTWIVNTTMIAQGQNRGIVQNFGVQDEVLFLQISLTENWLIFITRCSGPFWSSFPSWQLSGAVLVVDILATLFCIFGWFKGGHQTSIVAVIRIWMYSFGIFCLIAGVYYILSESSSFDRWMHGKHKERGTTRKLEDFVMQLQRTSTHHEAEGKVTS
What is the function of this protein?
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump.  The proton gradient it generates drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
Plasma membrane ATPase 2, Proton pump 2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CTL5A_DANRE
Sequence: EPRKFDPTFRGPVYNRGCTDVLCCVLFVIVILGYIALGTVAWIHGDPRKVIYPTDSTGQFCGQKGTPNAKKAILFYFNILKCASPAVLINLQCPTTQMCVSKCPDRFATYTDMQLLYRFNKSHWDYYKQFCKPGFNNPQKSVAQVLRDEDCPSMIVPSRPFLQRCFPDFITRNGTLTVANKTAFKDALDTARSVTELRDAANGITSIHEAKEVGMKIVEDYASCWYWIVIGLFIALVISLIFILLLRFTAGFLLWFIIFAVILLVAYGIWHCYWEFAVLRETPGADVTISDIGFQTDLHVYLQLSQTWLVFMVTLGLTEASIVLMLIFLRKRVRIAIALLREGSRAISYIMSALFYPIITFVLLAICISYWAMTALFLASSGDAVYKVASGNPNCKYANQTCSPESFNRTNITKQCPGAQCLFAFYGGESLYHRYIFILQLCNLLVFLWLVNFTIALGQCTVAGAFASYYWARRKPADIPPCPVFSSFSRALRYHTGSLAFGSLILAVVQLIRVILEYLDHKLKGAHNAFARFLLCCLKCCFWCLERFIRFMNRNAYIMIAIYGKNFCTSAREAFYLLMRNVVRVAVLDKVTDFLLFLGKLLIAGSVGVIAFFLFTRKIPIIQEEVPVLNYYCVPLLTVILGSYLIAHSFFSVYAMCVDTLFLCFCEDLERNDGTTAKPFFMSPGLKRILGKAEQSPKKSRG
What are the official names of this protein?
Choline transporter-like protein 5-A, Solute carrier family 44 member 5-A.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSP70_CERCA
Sequence: MVAIGIDLGTTYSCFGVFQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNTVFDAKRLIGRKYDDPKIMEDVKHWPFKVVSDGGKPKISVEYKEENKQFAPEEISSMVLTKMKETAEVILGTTVTDAVITVPAYFNDSQRQATKDAGRIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRATAGDTHLGEDFDNRLVSHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGIDLYTKVSRARFEELCADLFRQTLEPVEKALNDAKMDKNQIHVYVLVGGSTRIPKVQRLLQSFFCGKSLNLSINPDEAVAYGAAVQAAILSGDKSTEIQDVLLVDVAPLSLGIETAGGVMAKIIERNCRIPCKQTQTFSTYSDNQPGVNIQVYEGERVMTKDNNRLGTFDLSGIPPAPRGVPQIEVTFDVDANGNNLNVSAKEMSSGNAKNITIKNDKGRLSQAEIDRMVNEAGRYAEEDERQRNKIAARNNLESYVLAVKQAWTTLVDKLSEREKSEVTKACDDTIKWLDATRLADKEEYEDKMNTLTKLCTPIMTKLHSGGGAGQGASCGQQAGGFNGGHTGPTVEEVD
What are the official names of this protein?
Heat shock protein 70, HSP70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HFLD_VIBC3
Sequence: MANAIYDRTIAFAGICQAVALVQQVAKNGYCDSDAFETSLKAITCTNPSNTLEVFGHESQLKLGLECLVKGIDSTPSGSEITRYLISLMALERKLSGRRDAMSQLGDRIQMIERQLDHFDLFDDQMISNLASIYLDVISPIGPRIQVTGTPAVLQQTANQHKVRALLLSGIRCAVLWRQVGGRRRHLIFGRKKMIEQAQILLARI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FOLD_HALHL
Sequence: MPAQILDGKAIAAKRRALVGEAVGQRIERGLRRPGLAVILVGQNPASAVYVRNKRRACEEAGILSRAYDLDADVSEGELLERIDRLNADPEIDGILVQLPLPGHIDEQTVIERIDPVKDVDGFHPENMGRLALRLPGLRPCTPRGVMTLLHHTGIELEGRDAVVLGQSNIVGRPMTLELLNARCTVTVCHSRTRNVAERVRQADLVVASVGKPGLIQGDWIGEGAVVIDVGINRLDSGKLTGDVDFEAASQRASWITPVPGGVGPMTVATLLENTLDAARNRDELTAAAC
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PRPF_CUPNE
Sequence: MTHVPQIKIPATYIRGGTSKGVFFRLQDLPETAQVPGPARDALLMRVIGSPDPYGKQIDGMGAATSSTSKTVILSKSTRPDHDVDYLFGQVSIDQPFVDWSGNCGNLSAAVGPFAISAGLVDASRIPHNGVAVVRIWQANIGKTIIGHVPVTNGEVQETGDFELDGVTFPAAEVQLEFMDPAAEEEGAGGAMFPTGNVVDDLEVPAVGTLKATMINAGIPTIFVNAESIGYTGTELQDAINSDTRALAMFEDHPCYGALRMGLIKNVDEAAKRQHTPKVAFVRQAGDYVASSGKKVAAADVDLLVRALSMGKLHHAMMGTAAVAIGTAAAIPGTLVNLAAGGGERNAVRFGHPSGTLRVGAEAQQVDGEWAVKKAIMSRSARVLMEGWVRVPGDAF
What is the function of this protein?
Catalyzes the isomerization of 2-methyl-trans-aconitate to yield 2-methyl-cis-aconitate through a base-catalyzed proton abstraction coupled with a rotation about C2-C3 bond of 2-methyl-aconitate.
What are the official names of this protein?
2-methyl-aconitate isomerase, Cis-trans isomerase.
What is the protein family that this protein belongs to?
Belongs to the PrpF family.