PharMolix/UniProtQA huggingface dataset:
Protein: RECA_XYLF2
Sequence: MDENKKRALSVALSQIEKQFGKGSVMRMGDRVIEAVEAIPTGSLMLDLALGIGGLPKGRVVEIYGPESSGKTTLTLQAIAQCQKRGGTAAFIDAEHALDPIYAGKLGVNVDDLLLSQPDTGEQALEIADMLVRSGSIDIMVIDSVAALTPRAEIEGEMGDQLPGLQARLMSQALRKLTGNIKRSNTLVIFINQLRMKIGIMMPGQSPETTTGGNALKFYASVRLDIRRIGAIKKGDEIIGNQTKIKVVKNKLAPPFKQVVTEILYGEGISREGELIEMGVEAKLVEKAGAWYSYGGERIGQGKDNARGYLRENPHFAAKLEADLREKFEPTELSREEGDEDTLEDAM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_PARMW
Sequence: MTARQIQLGDITFANDRPFALLGGVNVLEDLDFALRCAGHYKQVCERLGIPLVFKASYDKANRSSIHSFRGPGLEAGLQILQAVKDTLGIPVITDVHSPEEAKAAAKVADIIQLPAFLARQTDLVRAMAETGAVINIKKPQFLSPEQIRNIVDKFRECGNEQLLICERGTNFGYDNLVVDMLGFGVMKRTCDDLPLIFDVTHALQCRDPGGAASGGRRSQVVDLAKAGMAVGLAGLFLEAHPDPNQARCDGPSALPLDQLEPFLTQVKAIDDLVKSQPMININ
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_SULNB
Sequence: MNYDVIVIGGGHAGIEASLASARMGVKTLLITILAEQIGASSCNPAIGGLAKGHLVREVDALGGEMGLCTDATGIQFRTLNASKGPAVRGSRAQIDMDEYRIYMRNVVLNTENLDVKQEIADGLIVEEGEVKGVTTQLGNRYTASKVIITAGTFLNGLIHIGDKKQTAGRQGEFASVELAEYLKGLGLNIGRLKTGTCARIDAKSVDTSVMEVQPGDTPPPPFSFRTDKSTFNPKQLPCYVAYTNERTHEIIESNFYRAPMFSGQIEGVGPRYCPSIEDKINRFRDRPRHQIFVEPQTIDETEYYINGMSTSLPIDVQLEMVRSVEGMKNAKIVRYGYAIEYDYVDPTELKHTLETKKIKGLYTAGQINGTTGYEEAAAQGLMAGINAALSIQGKEALILRRDEAYIGVLIDDLVTKGTKEPYRMFTSRAEYRLLLREDNADMRLSKYGKELGLLDDAYIAKFEEKQKNIEEALNYLQENYVTPTKEFLAKLEAIGAVKINDRTCWIDVIGRGDFNRDKLVSLLPEFDKYDDEVMGQILVEAKYSRYIEKQQMQIDQMKDMLKIKIPEDFTYKNVSGLSNEIVEKLEKANPTTLFAASEISGVTPAALEIIHVYIKMSQKGKI
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_VIBVU
Sequence: MQIKQNISLKPYHTFAIEQCSHYLVEVGSVDELVDIYANPDFRELPKLILGSGSNVLFTQPFSGVVVVNRLSGKTLSEDESFYYIHAEGGEDWPNLVEWCVQQGIGGLENLALIPGCAGSAPIQNIGAYGVEFKDVCQYVDILMLDDFSQRRLSAEECQFGYRDSVFKHALYNQCVVIAVGLKLPKTWQANNSYGPLQEIAEHELSPMSIFHKVCEVRREKLPDPKQIGNAGSFFKNPIIDKAHWQQLKAQFPNIVAYPAGEQMKVAAGWLIDQCDFKGVQVGGAQVHPKQALVLTNAQSCTAQDIIQLASLICDAVWDKYQIALEHEVRFISTVGETCLSELRVES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPA_KLEP3
Sequence: MSSTSLYAAIDLGSNSFHMLVVREVAGSIQTLSRIKRKVRLAAGLNSDNTLSAEAMERGWQCLRLFAERLQDIPPTQIRVVATATLRLAVNAEEFLAKAQEILGTPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRSLTKENFDLAEAAAREVLLPIADVLRYHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFSELNIQCMTLAGGALREGLVYGMLHLSVEQDIRSRTLRNIQRRFMIDTEQAQRVASLASHLLSQLDGSWELDPLSRDLLLSACSLHEIGLSVDFKRAPQHAAYLVNNLDLPGFTPAQKKLIATLLLNQTNAIDLSSLHQQNAVPPRVAEHLCRLLRLAILFASRRRDDLLPAIQLAAHDDQLTLTLPENWLAEHPLGREMVDQECQWQSYVHWTLRVTSGDTPR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: IF1_BACTN
Sequence: MAKQSAIEQDGVIVEALSNAMFRVELENGHEITAHISGKMRMHYIKILPGDKVRVEMSPYDLSKGRIVFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCMH_STRGA
Sequence: MATISPSPDLFTLVNVFGVAPEKQRELRDHLVQVTEDLIRHMPGFVSATFHLSRDGEQVVNYAQWRSEADFRAMHADPRLQPHFDYCRSVSRPKPIFCEVTHSFGATSPEGA
What is the function of this protein?
Oxygenase required for conversion of tetracenomycin F1 to tetracenomycin D3.
What are the official names of this protein?
Tetracenomycin-F1 monooxygenase, Tetracenomycin polyketide synthesis hydroxylase TcmH.
Protein: TRMA_MARMS
Sequence: MRPDQIQPEMYEKQLQDKQAELAKLMATLSLPEMEVFASQPTHYRMRAEFRIWHDGDDLYYAMFDSADPRTPIRTDQFLAASRLINELMPKLLDAVRDVPVLRYKLFQVDFLTTTTGEALISLLYHKPIDAEWNAAVQQLNNAFPACHFIGRSRKKKQIITRDFVMETLTVNGQKFHYQQVENSFTQPNAGISEKMLEWALDVTKEASGDLLEMYCGNGNFSIPLARRFDRVVATEISKVSVNSAQLNIAINGMHNVQVVKMASEDVSAALNGDVELPKSLVQAGVSELTPSVVLVDPPRAGLDDATVELIRKIDSILYISCNPETLKANLEALSNTHEVVRYAMFDQFPYTHHVETGVFLRRKAS
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: CLPP1_CORDI
Sequence: MNNNGMQMPQARYVLPSFIEQSAYGTKETNPYAKLFEERIIFLGTQVDDTSANDIMAQLLVLEGLDPDRDITMYINSPGGSFTSLMAIYDTMQYVRPDVRTVCLGQAASAAAVLLAAGAPGKRACLPNSRVLIHQPATQGTQGQVSDLEIQAKEIERMRTLMEQTLARHTGRSAEQVRIDTDRDKILTAEEAVEYGIVDQVFDYRKLNG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_WOLPP
Sequence: MKKVKTVGKNTKRFITGIVHIRATFNNTFVNVTDVCGNTLYQTSVGACGFSGSRKSTPYAAGKVADSAAKKVIERFGMKVVSVIIRGPGFGAEAAVKALRNCGLTVTSIADKTAIPHNGCRLRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y3691_MYCTU
Sequence: MGAGPVIPTRLATVRRRRPWRGVLLTLAAVAVVASIGTYLTAPRPGGAMAPASTSSTGGHALATLLGNHGVEVVVADSIADVEAAARPDSLLLVAQTQYLVDNALLDRLAKAPGDLLLVAPTSRTRTALTPQLRIAAASPFNSQPNCTLREANRAGSVQWGPSDTYQATGDLVLTSCYGGALVRFRAEGRTITVVGSSNFMTNGGLLPAGNAALAMNLAGNRPRLVWYAPDHIEGEMSSPSSLSDLIPENVHWTIWQLWLVVLLVALWKGRRIGPLVAEELPVVIRASETVEGRGRLYRSRRARDRAADALRTATLQRLRPRLGVGAGAPAPAVVTTIAQRSKADPPFVAYHLFGPAPATDNDLLQLARALDDIERQVTHS
What are the official names of this protein?
Uncharacterized membrane protein Rv3691.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AAEB_SHIDS
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGELEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGVMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVPDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLINKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_SHEAM
Sequence: MGENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDQDKLPTPHELRAHLDDYVIGQEKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGLIPEFIGRLPVVATLAELDEDALIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQKAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDESVVKGESAPILIYEQTESQAASGDQ
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RPOB_EHRCJ
Sequence: MSSSVTPTKYVLNSFNSVPRLSYAKSIDIKDSLTDLIKIQRDSYNAFIGVGQNTESGIKNIFESMFPIEDLLGRAVLEFVSYSIGEPQYDEYECIKRGITFSVPIRIVLRFIVWKVQEVSFKEVKYVVDEETSEKSIKYIKEQEVSIGDLPTMTPHGTFIINGIERVIVSQMHRSPGVFFDSDKGKTYSSGKLIYSARIIPYRGSWLDFEFDIKDILYFRIDRKRKLPVSLLLRALGLSNNDILNTFYDKIRYVKCEKGWIVPFVVDRFRGVRLSHDLVDVNGNVLVKANTRITLRMAKKLANDGLTEYLVPFAEIQGLFIANDLFDPSGNALIISAGENITSEHINKLELFDIKEIFVLNIDFLTVGPYILNTLFLDKNVTYEDALFEIYKVLRSGESPSLDTIKAFFDGLFFEKERYDLSTVGRIKLNDHLGLNVSEDITVLTKDDIIHVIKKLVLLRDGEGSVDDIDHLGNRRVRSVGEFIENQFRIGILRLERMIMDYMSSVNFDNAMPCDFVNPKILATVLKDFFSSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGQNIGLISSLAIYARINKHGFIESPYRKVDKGVVTDKVEYLLAMQESNYYIADASATLDENNQFVDDMLYCRHDGNFVMVKREEVDYIDVSPKQIVSVAASLIPFLENNDANRALMGSNMQRQAVPLLKADAPLIGTGMESIVAAGSGTVVLAKRGGIVHRVDGLYIVIRAFDQEKNEYLGVDVYNLRKFQRSNHNTCINQRPLVKPGDYVKANDVIADGSAIDQGELALGKNVLVAFMSWQGYNFEDSIVISSEVVKKDVFTSIHIEEFECVVRDTTLGPEKIMRSVPDINEDSLSHLDDVGIVNIGAEVSAGDILVGKVTPRPPISLPPETKLLVTIFGEKVFDCVDSSLYLPLDVEGTVVDVHVFVRRGVEENDRSLLIKQNEINGFIKERDYEIDVVSEYFYDELKRVLVNSGVQCNNQNVNDYLESTPKKDWWNVNLSDETVLLQINNLREKFDSMIQNAHSKFDQKIDKLNYGYDLPQGVLCIVKVFVAVKHNLQPGDKMSGRHGNKGVISRIVPVEDMPYLEDGTPVDIILNSLGVPSRMNVGQILETHFGWASVNLGKKIGHILDNIDELTISHLRNFLDQVYDGQDLKYNIQSMSDEDLLAFAERLRGGVPMAAPVFEGPKDSQISNLLKLADLDVSGQVDLYDGRIGEKFDRKVTVGYIYMLKLHHLVDDKIHARSVGPYGLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDIVGRVKIYESIIKGDSNFECGIPESFNVMVKELRSLCLDVALKQDKDFLSSEVNN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RNH2_ECO55
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CAMFF
Sequence: MIQSFTRLAVADNSGAKELMCIKVLGGSKRRYASLGDIIVCSVKKALPNGKIKKGQVVKAVVVRTKKEVQRANGSLIRFDENAAVILDNKKEPVGTRIFGPVGREVRYANFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ATPA_ALTMD
Sequence: MQLNSTEIAELIKKRIEQFNVSSEARNEGTIVAVTDGIIRIHGLADVMQGEMIELPGSRYAIALNLERDSVGAVVMGPYADLKEGDKVQSTGRILEVPVGNALLGRVVNTLGEPIDGKGAIDAAGFEPVEKIAPGVIERQSVDQPVQTGYKSVDAMIPVGRGQRELIIGDRQCGKTAMAVDAIINQKGTGIKCVYVAVGQKASTIANVVRKLEEHGALDHTIVVAASASESAALQYLAPYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVNEQYVENYTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLGGGIRLALAQYRELAAFSQFASDLDDATREQLEHGERVTELMKQKQYAPLSIANMGVSLFAVEKGFLKGIELNKILDFEAALHSYMNSEHADLMKTINESGNYNDEIASKLNDALTNFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: B3GA1_MOUSE
Sequence: MPKRRDILAIVLIVLPWTLLITVWHQSSLAPLLAVHKDEGSDPRHEAPPGADPREYCMSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSTQPGVVYFADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins.  Can also play a role in glycosaminoglycan biosynthesis.  Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule.  Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin.  Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Secreted.
Protein: ALM1_SCHPO
Sequence: MSSGGLEDDIQLVHEFLDVSFEDIKPLVSVNGFAVFISAIKTKVKDINALKDQLVLQEVNHEHKENVLTKKINFLEQQLQSSNNQAEESRNLISVLRNENESLKTNLENQNKRFDALTTENQSLRRANSELQEQSKIASEQLSIAKDQIEALQNENSHLGEQVQSAHQALSDIEERKKQHMFASSSSRVKEEILVQEKSALVSDLASLQSDHSKVCEKLEVSSRQVQDLEKKLAGLAQQNTELNEKIQLFEQKRSNYSSDGNISKILETDPTSIKELEEEVETQKRLTALWESKSSELQSEVAALQEKLTSQQSLYNNVTEELNNNKQQLLISENSLRELQEKYDSVVSELQVVKENKNTSVSAGVGLFSPLAQKLSAVQNPEFSFTKVYSDNMKLQQKVSSLKLQLDRLTNKFSSFCEQVKQRIPVVKQQRSEIVRNNIYMNFLSESLETSNNNLTKVQAELLSTKMRQEACYLQLTASRTQCSDLSREVICLMAELDHLNETKSRNVPATVQVALDEYAQNPSTASETLVNKELANFSSIKEAVSKTLELREKVRALECDVEIQKQTVQYQISNAVKENSNTLSEQIKNLESELNSSKIKNESLLNERNLLKEMLATSRSSILSHNSSAGNIDDKMKSIDESTRELEKNYEVYRNEMTAIQESLSKRNQDLLSEMEAIRKELENSKYQQQLSTDRLTNANNDVEAFKKEAKELRSINQNLQDIISRQDQRASKFAEELLHVNSLAERLKGELNASKGEKDLRKRTQERLISENDKLLAERERLMSLVSDLQTFLNQQQLSDAARKVKFESEKESLSLSLQKLKESNEKMSNDLHSLQKSLEKSGIEYSSRIKTLMLEKQSLSEDNRKLLDNQQMMEIKLQELNGVIELEKQRFSTLEAKFTQQKNTSYSEREALLESSLSDLQSKHTSLESQYNYSLRNIEQLQAASKLAEEMVERVKTEYDEYRLQTSESLEKNHLKITSLEQRIVILQDEIASSSLRCENITKDSETRVALLLEENKHLNNELSSHRNAEKQHLEKENDYKQQLLLVTEDLRKTREDYEKELLRHADARSTLQKLREDYTKALEQVEDLNKEIALKAGINESQPFPISEKEDPLRQEVYVLKKQNAMLLTQLQSSNLNFAEITSPSPDLDSVMKLGLSDLQNHVKRISKEMEIISCQRQLLFLENKKLKRTVESSNRVIADLQRGITEKDVSSTSESVGERSNYLNMVALLNESNKSLRENLERNEEVITELREKIETLKTDLANFRLNKEQLESQLQTEKAAVKKLENSNEEYKRHNQEILLSLNSSTSTSSDASRLKNELVSKENLIEELNQEIGHLKSELETVKSKSEDLENERAQNQSKIEQLELKNTKLAAAWRTKYEQVVNKSLEKHNQIRQQLSQKTSELEAKVAECHQLNEQLNKPSATPTATTQSEPSTVSLEEFNSTKEELSSTQRKLSEIMDILNTTKEELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLRSRIAKELQKNELLRKQNQVLQDQVKALQETVVSSEEAESASVHADTKDLENLKKTEEMLSVTFQVIFNESISDFSTSTADFTTFVQKEWEKRREILQKDVEEQVAQSHQKQLDNIRKELEMRNKLKLSMLEKNLARVRAELEQSKKKDSPAILSLEASKNTDSNKSNSEVPAAQVKEKKLIAKTHSVDTNSPPKRSSSDAGMDVSNDVKKAK
What is the function of this protein?
Maintains the proteasome and its anchor cut8 at the nucleus envelope and is required for kinetochore component proteostasis (PubMed:28974540).  Proper kinetochore stoichiometry ensures the correct attachment of kinetochores to spindle microtubules during cytokinesis (PubMed:28974540, PubMed:10660053).  Required for the localization of spindle assembly checkpoint (SAC) protein mad2 and bub1 to the nucleus envelope during interphase, but not their localization during mitosis (PubMed:28974540).
What are the official names of this protein?
Nucleoporin alm1, Abnormal long morphology protein 1, Sp8.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus envelope.
Protein: TRPF_BACVZ
Sequence: MKKPEVKYCGIRSKRDYELAAASGADYLGFIFAASKRRVTPGEVRKWKEKVLTDKKHVGVFVNETIENIAQIASDLALDVIQLHGDESPEDARRLRPLVRSEIWKALHHGEGTLRQMAQFAPAVDGYVIDSSVKGMRGGTGIAFSWARVPLYRKQAQNANKRCFIAGGVNPETITGLLRSRPCGIDLASGIEKNGQKDQTLIRLLEERMNHYVSISK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: DSZD_MYCGD
Sequence: MSATDLSPTSLREAFGHFPSGVIAIAAEVDGTRVGLAASTFVPVSLEPPLVAFCVQNSSTTWPKLKDLPSLGISVLGEAHDTAARTLAAKTGDRFAGLETESRDSGAVFINGTSVWLESAIEQLVPAGDHTIVVLRVSDIVINEAVPPIVFHRSAFRKLGA
What is the function of this protein?
An NADH:FMN oxidoreductase which supplies reduced FMN for the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds.  Can also use FAD.  Provides DszC and probably also DszA (DBT-monooxygenase and DBTO2-monooxygenase respectively) with reduced flavin (FMN and/or FAD).
What are the official names of this protein?
NADH:FMN oxidoreductase, FAD reductase (NADH), FMN reductase, Flavin reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACD3_BOVIN
Sequence: MENQVLTPHVYWAQRHHELYLRVELSDVQNPAISITENVLHFKAQGHGAKGDNVYEFHLEFLDLVKPEPVYKLTQRQVNITVQKKESQWWERLTKQEKRPLFLAPDFDRWLDESDAEMELRAKEEEQLNKLRLESQGSPETLTSLKKGYLFMYNLVQFLGFSWIFVNMTVRFFILGKESFYDTFHTVADMMYFCQMLAAVESINAAIGVTKSPVVPSLFQLLGRNFILFIIFGTMEEMQNKAVVFFVFYIWSTVEIFRYPFYMLSCIDMDWKVLTWLRYTVWIPLYPMGCLAEAVSVIQSIPVFNETGRFSFTLPYPVKIKVRFSFFLQIYLILLFLGLYVNFRYLYKQRRRRFGQKKKKIH
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  Involved in Rac1-signaling pathways leading to the modulation of gene expression.  Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (By similarity).
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3, 3-hydroxyacyl-CoA dehydratase 3, HACD3, Protein-tyrosine phosphatase-like A domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DNAS1_PIG
Sequence: MRAARLMGALLALAGLLQLALSLRIAAFNIRTFGETKMSNATLSNYIVRILSRYDIALIQEVRDSHLTAVGKLLNELNQDDPNNYHHVVSEPLGRSTYKERYLFVFRPDQVSVLDSYLYDDGCEPCGNDTFNREPSVVKFSSPSTQVKEFAIVPLHAAPSDAAAEIDSLYDVYLNVRQKWDLEDIMLMGDFNAGCSYVTTSHWSSIRLRESPPFQWLIPDTADTTVSSTHCAYDRIVVAGPLLQRAVVPDSAAPFDFQAAFGLSEQTALAISDHYPVEVTLKRA
What is the function of this protein?
Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:3782104).  Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity).  Among other functions, seems to be involved in cell death by apoptosis (PubMed:3782104).  Binds specifically to G-actin and blocks actin polymerization (By similarity).  Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
What are the official names of this protein?
Deoxyribonuclease-1, Deoxyribonuclease I, DNase I.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope.
Protein: SYE_BORPA
Sequence: MAQSAERPRPYAFMTANATRPVRTRFAPSPTGFLHLGGARTALFSWAFARHHQGVFVLRIEDTDVERSTPEAVQAILDSMDWLGMQPDEGPFYQMKRMDRYAEVLAGMLEAGTAYHCYCSPEEVDAMREAARAKGLKPRYDGTWRPEPGKTLPPVPADRKPVIRFRNPIDGATSWNDMVKGPISFDNGELDDLIIARPDGTPTYNFCVVVDDWDMGITHVLRGDDHVNNTPRQINILRALGATLPEYGHVPMILGPDGEKLSKRHGAVNVMEYDAQGYLPEAMINYLARLGWSHGDDELFTREQLVEWFDTRHLSKSASQWDPKKLNWVNAHYIKGMDDAELAGRVAPRVERRGGKPQAADLPAIMGLLKDRAETLEQLAEDAMLFCGEYQPAPAELAAQHLTETARAALADFAARARDTEWNRAAISALIKAVLADRGLKMPQLGIPLRVAVTGRAQTPAVDAVLELLGKETVLARLQAL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.