PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_STRPC
Sequence: MTKEFHHVTVLLHETVDMLDIKPDGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL27B_MOUSE
Sequence: MSKLLFLSLALWASRSPGYTETALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLFSTVPYMLNVTAVHPGGASSSLLAFVAERIIKPDPPEGVRLRTAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLPGQVESAPHKP
What is the function of this protein?
Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity.  IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells.  Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17).  It drives rapid clonal expansion of naive but not memory CD4 T-cells.  It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR.  Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
What are the official names of this protein?
Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_MYXXD
Sequence: MAPAVLKTVADVKDWTAGLRREGHRLALVPTMGFLHEGHLSLIREGRRRADVVAVSIFVNPTQFGPKEDLSRYPRDFEGDVAKCISAGAQAIFAPAGPEVMYPQGYQTYVEVTDVSQGLCGARRPGHFRGVATVVTKLLTLFRPEVALFGEKDYQQLQVIRALNQDLHLGADIVGMPTVREPDGLAMSSRNAYLSPEERQRALALSRGLKAAQALLREGTRESEPLVAAVRRELEAAGLREDYVELVDAERLTPLASVAPGQPARLLVAAFSGTTRLIDNMQLGGEENAGRV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ECO45
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: THN_PYRPU
Sequence: KSCCRNTWARNCYNVCRLPGTISREICAKKCDCKIISGTTCPSDYPK
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Thionin.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: IL1B_CERAT
Sequence: MAEVPELASEMMAYYSSNEDDLFFEVDGPKQMKCSFQDLDLCPLDGGIQLQISHEHYNKGFRQAVSVVVAMEKLRKMLVPCPQTFQDNDLSTLIPFIFEEEPVFLDTCNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDVEQQVVFSMSFVQGEESNDKVPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLECESAQFPNWYISTSQAENMPVFLGGTRGGQDITDFTMQFVSS
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: EIF3J_DROGR
Sequence: MADDWEFAADSKVVVKPNAANNINKWEGEDDDEDVKESWEDEEEKKDEEKPTKTEAPAKTKPNKVLKAKLLEQECLEKEEEAKRLANMSTEEKLAEKLRLQKIQEESDLKSALETFGLTSIDGGLDSFNPQSNEEFKEFGATLSWKIAQYKESPHFPQFIEDLVQALCVNLSTADLKKVKMSVEVLHSEKLKMEKVSVKNKGAAKNRGKATLRTENDDIDVYQKYGDDFTDDYDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_NEPAL
Sequence: VGFKAGVKDYKLTYYTPDYETLDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFFAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYVEKDRSRGIYFTQFWVSIPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSTELAAACEIWKEIKFVFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2099_ALIFM
Sequence: MYPHLVSLGISEPEKIERYSLRQEAHKDILKIYFSKQKGELFAKSVKFKYPRQVKNVLVDSGSHRYKETTEINRNLTLIIDELNKITRPEKETPTDVKKKILKDLRHLEKVVASKIEEIEKDLEKL
What are the official names of this protein?
UPF0325 protein VFMJ11_2099.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: BETI1_CHRSD
Sequence: MPKLGMQPIRRRQLIQATLETIDDVGLADATIARIAKRAGVSAGIISHYFGGKDGLLESAMRQILWDLGDAVARRRAQGVESPREHIRAIIDGNFDRSQVNKTVMKTWLAFWSVSMHRPDLQRLQRVNDRWLYSNLCHHFRRCLPRPEAQQAARGLAAMIDGLWLRGALAPQGIDVDRARQLAYDYVEEQLARSTSHAPTDA
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI 1.
Protein: RHOD_MOUSE
Sequence: MNASQVAGEEAPQSGHSVKVVLVGDGGCGKTSLMMVFAKGAFPESYSPTVFERYNATLQMKGKPVHLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNNLRKKRLEPVTYHRGHDMARSVGAVAYLECSARLHDNVEAVFQEAAEVALSSRRHNFWRRITQNCCLAT
What is the function of this protein?
Involved in endosome dynamics.  May coordinate membrane transport with the function of the cytoskeleton.  Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB.  Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling.  Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
What are the official names of this protein?
Rho-related GTP-binding protein RhoD.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane. Early endosome. Note=Colocalizes with RAB5 to early endosomes.
Protein: YI46_SCHPO
Sequence: MFKNLIFLFFIGLATAIRFNLTDLECSRLRGPHCGTYLLKVVGTNATYVGEKSFIGLDALTESKGEFFQRMLEQEPRLIPRLFTIAENDTANFTPLTFTTYLKTCNPQSIENAMIPFVNTVTSEISFDAWAYTAQNSSRITGLSNQLMNSTLYNVQVATCTPGFSALLLDSPTINVFNNEEGMPSWCQPIELTPVCPLDEGFN
What are the official names of this protein?
VEL1-related protein SPBC1348.06c.
What is the protein family that this protein belongs to?
Belongs to the VEL1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Intracellular soluble fraction.
Protein: T150B_BOVIN
Sequence: MWGYLSLLPMCLAFWAIAGIWTVFSLAVVNKAVNLTDGFPYISVCGNVPPQSCIFSQVLNIGAASAAWICILRYYQLRDWGVRKWHNQVILWTGLLCALGTSIVGNFQEKNQRATHLTGAFLAFFVGIVYFWLQLFLSWRMKNLPQPGAPWIGPLRLVLCSACFILEVAMVVLHSWSMRSVSAICEWVAAMLLFILFGLLAVDFSRLDSCTLCLQPGSGSLRPPPDSPTSLHVQL
What is the function of this protein?
Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity).  Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (By similarity).  May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (By similarity).
What are the official names of this protein?
Modulator of macroautophagy TMEM150B, Transmembrane protein 150B.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Localizes mainly at the plasma membrane where it concentrates at actin-rich focal adhesions (By similarity).
Protein: CAPSD_BPP22
Sequence: MALNEGQIVTLAVDEIIETISAITPMAQKAKKYTPPAASMQRSSNTIWMPVEQESPTQEGWDLTDKATGLLELNVAVNMGEPDNDFFQLRADDLRDETAYRRRIQSAARKLANNVELKVANMAAEMGSLVITSPDAIGTNTADAWNFVADAEEIMFSRELNRDMGTSYFFNPQDYKKAGYDLTKRDIFGRIPEEAYRDGTIQRQVAGFDDVLRSPKLPVLTKSTATGITVSGAQSFKPVAWQLDNDGNKVNVDNRFATVTLSATTGMKRGDKISFAGVKFLGQMAKNVLAQDATFSVVRVVDGTHVEITPKPVALDDVSLSPEQRAYANVNTSLADAMAVNILNVKDARTNVFWADDAIRIVSQPIPANHELFAGMKTTSFSIPDVGLNGIFATQGDISTLSGLCRIALWYGVNATRPEAIGVGLPGQTA
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=7 symmetry.
What are the official names of this protein?
Major capsid protein, Gene product 5, gp5, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the P22 phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Forms the capsid icosahedric shell.
Protein: ACSA_YERP3
Sequence: MSQIHKHPIPAAIAEHALITPEKYQHYYQQSVQNPDEFWGEQGKIIDWIKPYKTVKNTSFDPGHVSIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPDAVAGRIIDSHSKLVITADEGIRAGRAIPLKKNVDEALKNPAITSIKNVVVFQRTGNASYWEDGRDVWWHDLIKEASADCPPEEMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVVDKHKVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNSKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNLGNPQEGVAEGNLVITDSWPGQARTLFGDHDRFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPLATPDILHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLLEEKQSMQTPS
What is the function of this protein?
Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.  Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: FKBP_GIBZE
Sequence: MGVEKTIITQGSGPSPQVGQKVTMEYTGWLQKEDGTKGDQFDTSVGRGDFVVNIGVGQVIKGWDEGVTQMKLGEKATLHISPDYGYGPRGFPGAIPPNSTLIFDVELKKIG
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1, FKBP, FkbA, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQCF_BACSU
Sequence: MGVTQENKVIARTVLGAFGGKPKVTKYWDDNKNSSIDILSVSDQPQEGITSYSTLGLSDHSINYEVNGTPLRIEIVAAMESASDIYANVLSTCAFNIINSNFTCAPGVIFKNVISMYDQETDMKHIMFVPPFLWEEDLELLEFSNKNVTWLMALPISEGELQVAEKHGSDYLQDLLESKQIDIFDIKRESVV
What is the function of this protein?
Immunity component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  In situ neutralizes the toxic effect of cognate toxin YqcG (PubMed:34280190).  Neutralizes the toxic activity of cognate toxin YqcG upon expression in E. coli.  Does not have immunity protein activity on other LXG toxins (PubMed:22200572).
What are the official names of this protein?
Immunity protein YqcF.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIP4_DIURU
Sequence: MKLALVLSLIVSVAAAPTATLANGDTITGLNAIINEAFLGIPFAQPPVGNLRFKPPVPYSASLNGQKFTSYGPSCMQMNPLGNWDSSLPKAAINSLMQSKLFQAVLPNGEDCLTINVVRPSGTKPGANLPVMVWIFGGGFEVGGSSLFPPAQMITASVLMGKPIIHVSMNYRVASWGFLAGPDIKAEGSGNAGLHDQRLGLQWVADNIAGFGGDPSKVTIFGESAGSMSVMCQLLWNDGDNTYNGKPLFRAAIMQSGAMVPSDPVDGPYGTQIYDQVVASAGCGSASDKLACLRSISNDKLFQATSDTPGALAYPSLRLSFLPRPDGTFITDDMFKLVRDGKCANVPVIIGDQNDEGTVFALSSLNVTTDAQARQYFKESFIHASDAEIDTLMAAYPSDITQGSPFDTGIFNAITPQFKRIAAVLGDLAFTLPRRYFLNHFQGGTKYSFLSKQLSGLPVIGTHHANDIVWQDFLVSHSSAVYNNAFIAFANDLDPNKAGLLVNWPKYTSSSQSGNNLLQINALGLYTGKDNFRTAGYDALFTNPSSFFV
What are the official names of this protein?
Lipase 4.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: RL15E_HALMA
Sequence: MARSAYSYIRDAWKNPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKGK
What are the official names of this protein?
50S ribosomal protein L15e, 50S ribosomal protein LC12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: AT1A3_RAT
Sequence: MGDKKDDKSSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y514_SYNY3
Sequence: MTFSVPTQGKAFANISFLPYGVGPRDGGICLELHLGPYRILLDCGLEDLTPLLAADPGTVDLVFCSHAHRDHGLGLWQFHQQFPHIPILASEVTQRLLPLNWPDEFVPPFCRVLPWRSPQEVLPGLTVELLPAGHLPGAALILLEYHNGDRLYRVIYTGDYCLSHLQLVDGLALTPLRGLKPDVLILEGHYGNRRLPHRRQQEKQFIQAIETVLAKGRNILLPVPPLGLAQEILKLLRTHHQFTGRQVNLWAGESVARGCDAYQGIIDHLPDNVRNFAQHQPLFWDDKVYPHLRPLTDDQGELSLSAPSIVITTTWPAFWPSPAALPGLWTVFMPQLLTLPSCLVNFAWQDLEEFPKYELEDYLLADHSDGRNTTQLIHNLRPQHLVFVHGQPSDIEDLTSLEELQSRYQLHSPAAGNAVALPIGDRFVQPTPPPPQIYEGEIHELEPNKQIHHLGEVVIHLDGQILENSRWGKFGETGIVQARWQGEELVLRGISQRELLKQNQSSKRPVDFDCCANCRHFQHYHCRNPVSPLMGLEVRADGHCPVFESVASS
What are the official names of this protein?
Uncharacterized protein sll0514.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0047, MJ0162 and MJ1236.
Protein: GSA_LEGPL
Sequence: MSRSSDLFHKAQTIIPGGVNSPVRAFKGVGGEPVFFKSGKGAYLTDVDDKQYIDYVGSWGPLILGHCHPKVIEAVDNVLHSGMSFGAPTELEIQLAEKIASLMPSIEKIRMVNSGTEATMTAIRLARGFTNKNKFIKFNGCYHGHSDSLLVKAGSGLLTLGIPSTPGIPQCITEHTLTADFNNLEQVAQLFEKYPNDIATVILEPVPGNMGFILPKIEFLKGLRELCDQYNALLIFDEVMTGFRVGLHGAQGLFGIKPDITTLGKIIGGGMPVGALGGKREIMSFLAPEGPVYQAGTLSGNPLAMAAGLATLKEIEKINFFEDLSSTTNKLTEALSDAAENANIPLFAASLGGMFGFCFTDKNSVENYLDVASSDEVLFKKFFHAMLAQGVYFAPSMYEAGFVSSMHGDLEIQKTYDAAELVLNQLKSA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_STAA8
Sequence: MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APCD_NEOYE
Sequence: MSLVTQIIVNADDELRYPTIGELQSIQDYLTTGSNRIRIATIIRDKEKEIIQKASKQIFQLHPEYIAPGGNAAGSRKRSLCLRDYGWYLRLITYGVLAGDKDSIETIGIIGVREMYNSLGVPIIGMLDAIQCLKEASLEMLGQDDIRIISPYFDYIIRGMS
What is the function of this protein?
Allophycocyanin is a photosynthetic bile pigment-protein complex with maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin alpha-B chain, Allophycocyanin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the core of the phycobilisome.
Protein: SEC24_COCIM
Sequence: MAAPQEGYPPPHSDGQQGYGQPYGAPPAEADQPVAPPPAGAPATGGPTHGGRKKRAYAGQAFEFGSGANAALGGQLPGGGTYGGYPAPPQPQGYPPVPYPGQPAQPAPETYAAGEQLGAGGYQPPGPGYPAADVSQITQQMGQMSMGGQMPGRAPGATSLNQLYPTDLLAQSFNVAELDFPPPPVILPPNASVTPSPTANCSAKFVRSTLNAVPTTNSLLKKSRLPFALVIQPFTSLHDSEDPVPIVSDQIISRCRRCRSYINPFVTFLDHGHRWRCNMCNLTNDVPQGFDWDATAQQALDRWQRPELNHAVVEFVAPQEYMVRPPQPLVYLFLIDVSYSSVTTGLLATAARCIKESLDRIPNTDRRTRLGFIAVDSSLHYFTIPRDGSESSDPSMLVVSDLDEPFLPIPGDLLVTLTECRENIEIFLDKLQEMFQNTQNGGSAMGSALRAGHKLIGPVGGKLTVLTASLPNIGYGSLEMREDKKVLGTSKESSLLQTGNSFYKSFAVECSKQQISVDMFLFSSQYQDVASLSNLPRYTGGQTYFYPGWNAARSEDAIKFAKEFSDYLSSEIGLEAVLRVRATTGLRMSTFYGNFFNRSSDLCAFPAFPRDQAYVVEVAIDETVTKSVVCLQTAVLHTTCNGERRIRVLTLALPTTQSLADVYASADQTAIATYFSHKAVERTLGSGLEQARDALQAKIIELLSTYRKELAGGSVTGGGLQFPSNLRGLPLLFLALIKNLGLRKSAQIPTDMRSAALCLLSTLPLPLLIQYIYPKMYSLHDMPDDAGVPDPATGEIVLPPLCNLTSERLVPYGLYLIDDGQTQFLWVGRDAVPQLVQDVFGFPDKSQLRVGKQFLPELDNDFNERVRAVIQKSRDFRSRGVGSIIVPQLYVVKEDGEPGLRLWAQSMLVEDRADQGVSLQQWMSLLREKVIQ
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.