PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_NEIMF
Sequence: MQLNPAEISDLIKAKIENLSVNAEVRTRGTVVSVTDGIVRIHGLSDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYEHIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVGRGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPYSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEHEVEKLTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHPEVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TSR3_SULTO
Sequence: MKVYIIDYHRDDPKKCTGRKLIKLNFAELTRYGKGIILDPYSKRILSILDKDIALKTGITIVDTSWNSTSKIEFEKIKGEHRRLPILFAGNPTNYGIAYKLSSIEAVIASLYILNEVEEAIKIANIIKWGHTFLELNKELLESYRNKSENEILEIEREVIEKIIGEP
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGAL_STRMU
Sequence: MGIVIKDNLFYIHTKDSSLIIEERDGDLLLKHLGKKIEAYHFSNTVFEKDHAFSANPVADNRNYSYDTQRQIFGVHGFGDFRVPSLILQHDNNDLTRFKFKKAKIIKGGIKARGLPNPHSSESAQSLALILEDDLAKLRMTLYYTAYDDNATISTFVKFENLSDKPVILHRALSTMFDLPASHYDVITFQGAYAREKTLRRHQIEQGLFKIGSNRGASGHAQTPSLILTEHDSNEFYGEALALQLIYSGNFQAFVQKNQLNEVRLGIGINDDNFSWDLQANQSFETPVALITYTDKGLTDLTQESHNFIKRHIIPKNFANKERPILINNWEATYFDFNRSQLLGLADEARKLGIELFVLDDGWFGHRFDDNSSLGDWFVNEEKLGGSLDSFIKEIHDRGLQFGLWFEPEMVSVDSKLYRAHPDWVIQADQREHTYSRNQLVLNLANPDVVAYIKTVLDKLLTENTIDYVKWDYNRNITNIGNGRTYLETQMQSHAYILGLYNIVSYLTTKHDKVLFESCSGGGGRNDLGMMCYFPQVWSSDNTDAIARLPIQYGSSYLYPTISMGAHVSAVPNHQMNRHTPLTTRGHVAMMGNLGYELDLAILTKNEKKAVANQIKHYKKIRSVVQFGKLYRLINPEVGINEVAVQYTYDNQVLVTYVRIQSTIEMMETTVKLRGLDADAIYVLIETGQIFSGAELMYAGLTIDMPQGDYLSKQYYFIKK
What are the official names of this protein?
Alpha-galactosidase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
Protein: RPOB_SALHS
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PDXA_NOSS1
Sequence: MYQLNQNQTVNTPQKYRPRLALTVGDPGGIGAEVILKALADLEIGHNYDLTVVSNKNLLQETYKQLSSMENLLPLADPNLLKIIDVTVDRETARQINLGTGNAASGAASFAYMDYAIAQTLAGNFDGIVTGPIAKSAWKAAGYNYPGQTELLAQKSGVERFGMLFVARSPYTGWTLRALLATTHIPLRQVADTLTPQLLTQKLDLLVECLEKDFGITSGRIAIAGLNPHSGEQGQLGTEELDWLIPWLESERQKRPHFQLDGPIPPDTMWVKPGQAWYGNAIVQHPADAYLALYHDQGLIPVKLMAFDRAVNTSIGLPFVRTSPDHGTAFDIAGQGIADATSMKEAISLAAELVCQRLHLEK
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C82E4_NICTO
Sequence: MLSPIEAIVGLVTFTFLFYFLWTKKSQKPSKPLPPKIPGGWPVIGHLFHFNDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTNDAIFSNRPAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNLYTRIDGNSSTINLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMILSMEFVLWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHINKREKMEVNAEGNEQDFIDVVLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALLINNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVEDCVVSGYHIPKGTRLFANVMKLQRDPKLWSDPDTFDPERFIATDIDFRGQYYKYIPFGSGRRSCPGMTYALQVEHLTMAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRLAPELY
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:17102129).  Catalyzes the demethylation of nicotine to form nornicotine (PubMed:17102129).
What are the official names of this protein?
Nicotine N-demethylase CYP82E4, NND, Cytochrome P450 82E4, NtomCYP82E4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family. CYP82E2 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FTRC_MAIZE
Sequence: MTSTVTTTVGCGGLPVRPLSTATRGRPRRCAVRAQAAGADASNDKSVEVMRKFSEQYARRSNTFFCADKTVTAVVIKGLADHRDTLGAPLCPCRHYDDKAAEVAQGFWNCPCVPMRERKECHCMLFLTPDNDFAGKDQVISFEEIKEATSKF
What is the function of this protein?
Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
What are the official names of this protein?
Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, FTR-C, Ferredoxin-thioredoxin reductase subunit B, FTR-B.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin thioredoxin reductase beta subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HJC_THEKO
Sequence: MRYRRGASAERELVKLLESKGFAVLRSAGSHKIDLVAGNGKEYLCIEVKSTRSRKLYLPIEDVEKLVEFAGRFGGRPVLAVKFVNVGWRFYGPNRLEHGEKSYKIDLETPFMTLDGLLGKQRTLEGVL
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination.  Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
What are the official names of this protein?
Holliday junction resolvase Hjc, Hjc.
What is the protein family that this protein belongs to?
Belongs to the Holliday junction resolvase Hjc family.
Protein: YAD7_YEAST
Sequence: MDMEIEDSSPIDDLKLQKLDTNVYFGPCEILTQPILLQYENIKFIIGVNLSTEKIASFYTQYFRNSNSVVVNLCSPTTAAVATKKAAIDLYIRNNTILLQKFVGQYLQMGKKIKTSLTQAQTDTIQSLPQFCNSNVLSGEPLVQYQAFNDLLALFKSFSHFGNILVISSHSYDCALLKFLISRVMTYYPLVTIQDSLQYMKATLNISISTSDEFDILNDKELWEFGQTQEILKRRQTSSVKRRCVNLPENSTIDNRMLMGTTKRGRF
What are the official names of this protein?
Uncharacterized protein YAL037W.
Protein: CYOE_RUTMC
Sequence: MIIPLISDLLALCKLKVVALILLTAEVGMFLAVPAPYLPNGLLVLSASIGISMAAASAAVFNHVVDEQIDAQMSRTNKRPLPQGKVSRNQALMWGVFLGLVGLGILQLFVNTITMVLTFVSLIGYAIIYTLYLKRATPQNIVIGGAAGAAPPVLGWTAVSGTQGIEYACLLFLIVFIWTPPHFWALAIHRVEEYKKVDVPMLPVTHGLAYTRTQILLYTVLLLLVSLLPYLASMSGLIYLVVAIALGIRFLMYAIKIYNNPDDKRIAWCTFVYSINYLMLLFVTLLFDHYWLILPLEVF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VA5_BRACH
Sequence: TEGGAVHTMCQYTSPQPSPNCGTYSNAHITAADKETILKVHNDERQKVKAGQETRGNPGPQPAASNMPDLTWDNELAAIAQRWVNQCKIGHDGCRNVERYQVGQNIAMSGSTAKGPCNMNNLVQMWINEVNALNAADVSSMPSDGNYFMKIGHYTQLVWGKTTKVGCGIIQFLDGKFYKCYLACNYGPAGNMFGAPIYQ
What are the official names of this protein?
Venom allergen 5, Antigen 5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KGD_MYCS2
Sequence: MSSSPSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYSPEPTTDSASNGRTTTAAPVTPPTPAPAPAPEPKAAPKPAAKTEAKPAKPAKSATPAKGDESQILRGAAAAVVKNMNASLEVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVKKFPNMNRHFAVVDGKPTAITPAHTNLGLAIDLQGKDGNRSLVVAAIKRCETMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTLGTVHSVPRLMQGQGAIIGAGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTIHQLLLDDDFFDEIFRELGIPYEPVRWRTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVNSHGLTLWDLDREFKVDGFAGVQRKKLRDILSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAVIDQCAEHGLDEVVIAMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGTYIQMFGDNDIEVSLTANPSHLEAVDPVLEGLVRAKQDLLDTGEEGSDNRFSVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIVVNNQIGFTTAPTDSRSSEYCTDVAKMIGAPIFHVNGDDPEACAWVARLAVDFRQAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRGSRKAYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHEIEPSESVEADQQIPSKLATAVDKAMLQRIGDAHLALPEGFTVHPRVRPVLEKRREMAYEGRIDWAFAELLALGSLIAEGKLVRLSGQDTQRGTFTQRHAVIVDRKTGEEFTPLQLLATNPDGTPTGGKFLVYNSALSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHGKDGIQRPLIVFTPKSMLRNKAAVSDIRDFTESKFRSVLEEPMYTDGEGDRNKVTRLLLTSGKIYYELAARKAKENREDVAIVRIEQLAPLPRRRLAETLDRYPNVKEKFWVQEEPANQGAWPSFGLTLPEILPDHFTGLKRISRRAMSAPSSGSSKVHAVEQQEILDTAFG
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle.
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: CYC2_DROME
Sequence: MGVPAGDVEKGKKLFVQRCAQCHTVEAGGKHKVGPNLHGLIGRKTGQAAGFAYTDANKAKGITWNEDTLFEYLENPKKYIPGTKMIFAGLKKPNERGDLIAYLKSATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c-2, Cytochrome c-proximal.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: ORC1_PLAF7
Sequence: MTPKKKIFQNFQANDNEILSPTKKGIKLNVSKLNILNFENTIITKEKTNYEYKASLNKEIDEVLNNNNIINTHNNKKNNLNLYDYNNIKNSTHEFYIDLNEQNKQTIKYNDNKFTPINKKEKYNLDETSSSSISSSLTNISSSLTNISSSLTNISSSLSNSLDEKKKKKKIKKNNSTIINILNNNNNNSNIHHNNKHNIYNKYNISKKPQNKEIHTLPSNHQIKKKSNNTYNTCQQKMKKNISKKNTHSIKNNQNDKNKEKNKEKDKNIKKDRDKDIQTKRTSHQSQDQNNHFERRILRSYTRNNDNVKNNLKNNINNNNTLKRSSQSVRIDSDLSSAHQNKRIKYDEKNIIHRNNNNNNNNNNKTTSNNHNKNNKINNNNPSENYKKQTDTKHTNNTQNNKYNKTKTTNTFKHPSKDHTDVNTKTFKSRYINTYTMEEVQKSIKSNTIKLVQENSCEYQDGIIYESIQINDEEYSIGEDVLIFYTPNNNTYNAKSDDKKNQNNNNIKENIYLLKKGKISSFYKSTNSKVIEVEICFYYDESDEQRIRELEKKQTSRRCKEDFNIYLDDDTKYYNLLGNIHFTILDANYIYKKIYVYNEIETFEEDTHARKGKNKFLCTHFIKDKEDRLCFIPNEDHWDNLVLGSSDLYYYFANEKKLNKNKSLKLIIEKLKINDKINDTQANQKKNNKKEYMNKAQTTTNVKANTHTKTLNDHNKSKTTKNKESSSTSFLQDVKKKSDPHNNDFQSSLKEDQENYYINLLKNIKDPTDKAIRMMQLDVVPKYLPCREKEIKEVHGFLESGIKQSGSNQILYISGMPGTGKTATVYSVIQLLQIKSRKKLLPSFNVFEINGMNVVHPNAAYQVFYKQLFNKKPPNALNSFKIIDRLFNKSQKDNRDVSILIIDEIDYLITKTQKVLFTLFDWPTKINSKLILIAISNTMDLPDRLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERLENCKEIIDHTAIQLCARKVANVSGDIRKALQICRKAFENKRGHKIVPRDITEATNQLFDSPLTNAINYLPWAFKIFLTCLIIELRIINEFVIPYKKVVNRYKILIETSGKYIGMCSDNELFKIMLDKLVKMGILLIRPYIPLENISKNKSKEALLGFNESSKKGNNQKITRAQVSPDIDKESGDMGIELNVETQLIITALMKDPDCSKKLNFY
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication and thus may regulate the initiation of DNA replication (Probable).  DNA-binding may not be ATP-dependent (PubMed:19633266).  In a SIR2A/Sir2-dependent manner, binds to and silences telomers and subtelomeric repeat regions (TAREs) (PubMed:18525026, PubMed:22379140, PubMed:24018145).  In a SIR2A/Sir2-dependent manner, binds to promoters of var genes localized next to TAREs resulting in their silencing (PubMed:22379140).
What are the official names of this protein?
Origin recognition complex subunit 1, PfORC1.
What is the protein family that this protein belongs to?
Belongs to the ORC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Nucleus, nucleolus. Note=At the late ring stage/early trophozoites, co-localizes with SIR2A/Sir2 to telomeres and subtelomeric regions (TAREs) in the nuclear periphery (PubMed:18525026, PubMed:22379140, PubMed:26094711). Also, partially localizes to the nucleolus (PubMed:18525026). In trophozoites and early schizonts localizes throughout the nucleus (PubMed:18525026, PubMed:26094711). During early-to mid replicating trophozoite stages, colocalizes with PCNA1 and ORC1 to distinct nuclear foci which probably are DNA replication origin sites (PubMed:18554328, PubMed:19633266). In schizonts, relocalizes to the nuclear periphery and cytoplasm (PubMed:18525026, PubMed:26094711). In late schizonts, expression decreases probably due to proteosome-mediated degradation (PubMed:18554328, PubMed:26094711).
Protein: RS9_SALA4
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GLMM_CAUVC
Sequence: MSKRAYFGTDGIRGQANKHPMTAEVALRVGLAAGKLFRSQDERRHLVVIGKDTRLSGYMIEPALVAGLTSVGLDVRLFGPLPTPAVAMMTRSMRADLGIMISASHNSFADNGIKLFGPDGYKLSDAQELGIEALMDQGLQEGLAAPRELGRVKRIDDAQARYVEIVKATFPRHLNLSGLRIVIDCANGAAYKVAPTALYELGAEVITLGVSPDGTNINEECGSTHPEAMAKMVREYRADIGIALDGDADRLVICDEKGVVVDGDQIMAIIAAASHKAGTLKGGGVVATVMSNLGLERQLNTMGLSLERTAVGDRYVMQRMREGGFNVGGEQSGHLILSDFSTTGDGLIAALQVLAVMVETDKPMSALGRQFEPVPQLLENVRFVGGKPLEAAAVKEAIADGEAQLNGAGRIVVRASGTEPLIRIMAEGDDPALVKKVVKSIASAVKAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SDHF2_DEBHA
Sequence: MFRNIQKRNISSSGRVLLNHGKPQNPVYNAELTMKIEPIQRTGESIDVKRARLVYQSRKRGILESDLLLSRFAKRYLSGFSQEELDEYDKLLDEPDWDIYYWATKNYDVTPLPDKWKNSKILKLLQEDAENKEKEILRMPEL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IXTPA_STAAC
Sequence: MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: DTD2_MOUSE
Sequence: MADGGRVAQARALLQQCLHARLQVRPADGDAAAQWVEIRRGLVIYVCFFKGADTDLLPKMVNTLLNVKLSETETGKHVSILDLPGDVLIIPQATLGGRVKGRSMQYHSNSGKEEGSELYSQFVSLCEKAVANNTKSVEAGVAVAHGTYGNRQVLKLDTNGPYTHLIEF
What is the function of this protein?
Deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids.  Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr), has no activity on correctly charged L-tyrosyl-tRNA(Tyr).  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.  In contrast to DTD1, deacylates L-Ala mischarged on tRNA(Thr)(G4. U69) by alanine-tRNA ligase AARS.  Can deacylate L-Ala due to a relaxed specificity for substrate chirality caused by the trans conformation of the Gly-Pro motif in the active site.  Also hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly) in vitro, although in vivo EEF1A1/EF-Tu may protect cognate achiral glycyl-tRNA(Gly) from DTD2-mediated deacetylation.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase 2, Animalia-specific tRNA deacylase, ATD, D-tyrosyl-tRNA deacylase 2, L-alanyl-tRNA deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_CHRSD
Sequence: MTPTPIQNAPQSAVTRQALALAGVFQAAAVVDQLARTGQCDERAWNTLIRATLDTNPDSFATIYGGHHNNLRLGIDTLSAVMNRQHSDPAVMRYGFSLVLLMQKLRKDDAMMASLGERLTRIQGQAEHFGDTHENVIASLGQLYQDTLSTFRYRIVVQGDPSLLQSRMMPERVRAALLTGVRFALLWHQQGGRRWKLLFQRQGIKKSLAALDGH
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SURA_ECOL6
Sequence: MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: Y248_STRZJ
Sequence: MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKIYQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTAVADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SPJ_0248.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: TXC3B_CUPSA
Sequence: GFGSLFKFLGKKVLKTVAKQAAKKQME
What are the official names of this protein?
Cupiennin-3b, Cu-3b, Short cationic peptide-3b, SCP-3b.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.