PharMolix/UniProtQA huggingface dataset:
Protein: APBB3_RAT
Sequence: MLGKDYMLAIILVNCDDDLWGDQNLEGETGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWELAEDPGTGKEGIWELRPPKGRSFSSLDSSLNRSNSLTWYNEDSYVRSLEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQARNRSQPHDGAWGEGQNMLMVLKKDAMSLLNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVAGDKDSCMLKCHVFRCDVPAKAIASRLQGLCAQILSERVGLSGEAACCSPDPISPEDFPRQVELLDAVSQAAQKYEALYMGILPVTKAMGMDVLNEAIGTLTGRGDRKTWVPAMLSVSDSLMTAHPIQAEAGAEEEPLWQCPVRLVTFIGVGHDPHTFGLIADLGCQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPPPLLKGGVGGAGAAPRKRGVFSFLDAFRLKPLFSICPKLILEGWGKRLYTLPVPRVL
What is the function of this protein?
May modulate the internalization of amyloid-beta precursor protein.
What are the official names of this protein?
Amyloid-beta A4 precursor protein-binding family B member 3, Protein Fe65-like 2, Fe65L2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SH3R1_RAT
Sequence: MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVDELPSNILLVRLLDGIKQRPWKPGPGGGGSTTCTNVLRAQGSTVVNCGSKDLQSPQCGQQPRVQAWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGVHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDTAECPSATAAQSSSASKHSDTKKNTRKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPTDVPYQAALGTMNPPLPPPPLLATTVLASTPSGATAAAVAAAAAAVAAGVGPRPAVGSTEQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVPMSTAGQASRGVTMVSPSTAGGPAQKPQGNGVAGNPSVVPTAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAVRTVAAHNQERPTAAVTPIQVQNAACIGPASVGLPHHSLASQPLPPMVGPAAHIAAVNINRTSVPLACAAGASSLASPNMTTAALETEPSGRTVTILPGLPTSPESAASACGNSSAVKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLDVELGSGEVPLQGAVGPELPLGGVHGRVGSCPTDGDGPVAAGTAALAQDAFHRKTSSLDSAVPIAPPPRQACSSLGPVMNEARPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity.  In the absence of an external substrate, it can catalyze self-ubiquitination.  Stimulates ubiquitination of potassium channel KCNJ1, enhancing it's dynamin-dependent and clathrin-independent endocytosis (By similarity).  Acts as a scaffold protein that coordinates with MAPK8IP1/JIP1 in organizing different components of the JNK pathway, including RAC1 or RAC2, MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/or MAPK9/JNK2 into a functional multiprotein complex to ensure the effective activation of the JNK signaling pathway (PubMed:12514131).  Regulates the differentiation of CD4(+) and CD8(+) T-cells and promotes T-helper 1 (Th1) cell differentiation.  Regulates the activation of MAPK8/JNK1 and MAPK9/JNK2 in CD4(+) T-cells and the activation of MAPK8/JNK1 in CD8(+) T-cells.  Plays a crucial role in the migration of neocortical neurons in the developing brain.  Controls proper cortical neuronal migration and the formation of proximal cytoplasmic dilation in the leading process (PCDLP) in migratory neocortical neurons by regulating the proper localization of activated RAC1 and F-actin assembly (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF1, Plenty of SH3s, Protein POSH, RING-type E3 ubiquitin transferase SH3RF1, SH3 domain-containing RING finger protein 1, SH3 multiple domains protein 2.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell projection, lamellipodium. Golgi apparatus, trans-Golgi network. Note=Colocalizes, with AKT2, in lamellipodia. Colocalizes, with HERP1, in trans-Golgi network.
Protein: YDIB_SALTY
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CAIB_ECOLI
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTIP3_ARATH
Sequence: MQRPPPEDFSLKETRPHLGGGKLSGDKLTSTYDLVEQMQYLYVRVVKAKELPGKDMTGSCDPYVEVKLGNYKGTTRHFEKKSNPEWNQVFAFSKDRIQASFLEATVKDKDFVKDDLIGRVVFDLNEVPKRVPPDSPLAPQWYRLEDRKGDKVKGELMLAVWFGTQADEAFPEAWHSDAATVSGTDALANIRSKVYLSPKLWYLRVNVIEAQDLIPTDKQRYPEVYVKAIVGNQALRTRVSQSRTINPMWNEDLMFVAAEPFEEPLILSVEDRVAPNKDEVLGRCAIPLQYLDRRFDHKPVNSRWYNLEKHIMVDGEKKETKFASRIHMRICLEGGYHVLDESTHYSSDLRPTAKQLWKPNIGVLELGILNATGLMPMKTKDGRGTTDAYCVAKYGQKWIRTRTIIDSFTPRWNEQYTWEVFDPCTVVTVGVFDNCHLHGGEKIGGAKDSRIGKVRIRLSTLETDRVYTHSYPLLVLHPNGVKKMGEIHLAVRFTCSSLLNMMYMYSQPLLPKMHYIHPLTVSQLDNLRHQATQIVSMRLTRAEPPLRKEVVEYMLDVGSHMWSMRRSKANFFRIMGVLSGLIAVGKWFEQICNWKNPITTVLIHLLFIILVLYPELILPTIFLYLFLIGIWYYRWRPRHPPHMDTRLSHADSAHPDELDEEFDTFPTSRPSDIVRMRYDRLRSIAGRIQTVVGDLATQGERLQSLLSWRDPRATALFVLFCLIAAVILYVTPFQVVALCIGIYALRHPRFRYKLPSVPLNFFRRLPARTDCML
What is the function of this protein?
Required for proliferation and differentiation of shoot stem cells in the shoot apical meristem (SAM), thus determining the appropriate balance between the maintenance of shoot stem cells and their differentiation into other aboveground plant parts via the control of subcellular localization and intercellular trafficking of STM in the shoot apex (PubMed:29742441).  Prevents intracellular trafficking of STM to the plasma membrane in cells in the peripheral shoot meristem region thus facilitating STM recycling to the nucleus to maintain stem cells (PubMed:29742441).  May function as a signaling molecule by regulating the trafficking of other regulators (PubMed:29259105).
What are the official names of this protein?
FT-interacting protein 3, Multiple C2 domain and transmembrane region protein 3.
What is the protein family that this protein belongs to?
Belongs to the MCTP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Vesicle. Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y160_AERHH
Sequence: MSIKEWPEDERPREKLLRQGPGGLSDAELLAIFLRTGVSGLSAVDLSRHLLQQFGSLRALLGAEQRAFCAAHGLGPAKYAQLQAVLEMGKRHLAEQLQRGDPLTSPQLTRDYLQAQLRDRPREVFALLLLDNQHRVIQFVELFYGTLDSASVWPREIVQIALKHNAAAVILAHNHPSGVAEPSRADRQITDRITAALALIDIRVLDHLVIGDGITVSFAERGWL
What are the official names of this protein?
UPF0758 protein AHA_0160.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: NTAQ1_DROAN
Sequence: MTTDFLFPKIADCSYVSCYCEENVWKLCEQVKRTRPEELSKCYAVFVSNEGRTVPLWRQKAGRGDDQVVIWDYHVFFMHNPSPNRCLVFDLDTTLPFPTYFHKYVTETFRSDLALRPEHHRFFRVIPADTYLIEFSSDRRHMRRPDGSWIKPPPSYPPILSNTNLHCLGDFICMSAGKGPGAVYSLSEFVHNFYKSPHVMAQNNK
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, Protein tungus.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: O51S1_HUMAN
Sequence: MSTLPTQIAPNSSTSMAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQPALHRPMHFFLFLLSVSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMESSVLLAMSIDRALAICRPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQVLTHSYCLHPDVARLACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESREDRWKAGQTCAAHLSAVLLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYSVKMKEIRKRILNRLQPRKVGGAQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51S1, Olfactory receptor OR11-24.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPLA_ECO45
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNSDLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB23_PEA
Sequence: MATQALVSSSSLTFAAEAVRQSFRARSLPSSVGCSRKGLVRAAATPPVKQGGVDRPLWFASKQSLSYLDGSLPGDYGFDPLGLSDPEGTGGFIEPRWLAYGEVINGRFAMLGAVGAIAPEYLGKVGLIPQETALAWFQTGVIPPAGTYNYWADNYTLFVLEMALMGFAEHRRFQDWAKPGSMGKQYFLGLEKGFGGSGNPAYPGGPFFNPLGFGKDEKSLKELKLKEVKNGRLAMLAILGYFIQGLVTGVGPYQNLLDHVADPVNNNVLTSLKFH
What is the function of this protein?
May channel protons produced in the catalytic Mn center of water oxidation into the thylakoid lumen.
What are the official names of this protein?
Chlorophyll a-b binding protein 3, chloroplastic, LHCII type III CAB-3.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FOLD_SCHPO
Sequence: MPIQLGLQRMLQLLKHLGNPQESFCAVQIAGTNGKGSICSYIYTSLLQAAIKTGRYTSPHFLEPRDTISINGQIASEEIFNTCWKQVIEVDRRFRTKATEFELLTATAFQCFHHSGVRVAVIETGMGGRLDATNVFEEPVLSIISRICLDHQAFLGNTLEAIAKEKAGIFKKNVPCVVDGLNEVNVLNQLKLSAEETRAHPFYLAKGKSGENKNEWIINTPNWGTNTFSTPLKGDYQGQNLACAVTALDILSSSFSIMLPHVQNGVKNTSWPGRLDIRSVPSLGDILFDGAHNKEAAIELAKFVNSQRREHNKSVSWVVAFTNTKDVTGIMKILLRKGDTVIATNFSSVSGMPWIKSMEPEVIKNSISSESSVECYTADNLTISEILRLAKEKNSSVIVCGSLYLLGDMYRYLKLDV
What is the function of this protein?
Glutamate-adding enzyme which catalyzes the binding of the first glutamyl side chain to dihydropteroate.  Leads to the de nove synthesis of tetrahydrofolate.  de novo (By similarity).
What are the official names of this protein?
Probable dihydrofolate synthetase, DHFS.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: GTPB6_MOUSE
Sequence: MLFLRAAVLPGFWLPRVRRVQLVRSPAVTLPSPVRTVHAGSRVWGSAWAGGGPVRGGGEEDPREDEEEEEDELLRAPPLLPLDTQRVCVLHPDVKRPAGKKPRSTAEWQVAEAAALVRALPGWSVASTLVVPSAAPGSRLVFGKGNFQDVTEKIKGCQDITSVFLNVERMAPPTKKELESAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLLRSSVNTDSGQQDQQGWGSRYIMGSGESPTELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTTLIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLRILYVDTIGFLSQLPHNLIHAFSATLEDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLHLPPALLESALEVHSKVDLVPGYTPPCSGALAVSAISGRGLDELKAALEASVLRATGRQVLTLCVRLGGPQLGWLYKEAVVQQVQELPEGDAAHVTVVITQAAYGRFRKLFPIDAPSALPH
What are the official names of this protein?
Putative GTP-binding protein 6.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
Protein: NUSB_BUCCC
Sequence: MKSKRRKARELAIQVLYSWQISKKIVLFETEKYVIEQNKKYSLDKIYFHKIVTGVIKNIFYIDKIIKKNISKKKNRLDYIEQAILRLASYEIIKRLDIPYKVIINEGIELAKIYGSNKSHKFINSILDKIITNKNNIKIKNF
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y4436_DICDI
Sequence: MDSISVPLQFCLMRVQEAVPGKPHFSVERLLIRVTYSDERISHPIGNPEA
What are the official names of this protein?
Putative uncharacterized protein DDB_G0292498.
Protein: PSA7B_ORYSJ
Sequence: MARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGSDTVVLGVEKKSTPKLQDSRSVRKIASLDTHIALACAGLKADARVLINRARVECQSHRLTVEDAVTVEYITRYIAGLQQKYTQSGGVRPFGLSTLIVGFDPYTDKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYKETSGKETIKLAIRALLEVVESGGKNIEIAVMTQKDGLRQLEEAEIDEYVAEIEAEKAAAEAAKKGAPKET
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-B, 20S proteasome alpha subunit D-2, 20S proteasome subunit alpha-4-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PA12A_VESVE
Sequence: FNPCPYSDDTVKMIILTRENKKHDF
What is the function of this protein?
Catalyzes the hydrolysis of glycerophospholipids such as phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine) and has a moderate activity to hydrolyze lysoglycerophospholipids such as lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine), but is unable to hydrolyze sphingomyelin.  In addition to acting as an allergen, it possesses a potent hemolytic activity on red blood cells of mice (98. 8% of hemolysis at 3. 0 ug/ml).
What are the official names of this protein?
Phospholipase A1 verutoxin-2a, PLA1, VT-2a.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURBA_XENLA
Sequence: MADGDSGSERGGSSGGPGGFSQHMSREQETQELATKRLDIQNKRFYLDVKQNAKGRFIKIAEVGAGGSKSRLTLSMGVAAEFRDYLGDFIEHYAQLGPSSPEQIAQASGEDGAGGPGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTINRGPGFSGGAGGGAGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDEGVGLGGAGGGGGGGMYGELPEGTSITVDSKRFFFDVGSNKYGVFLRVSEVKPSYRNSITVPLKAWGKFGGAFCRYSEEMKEIQERQRDKMYERRGPGDRERSLGPGGGGDDSETEDVDDD
What is the function of this protein?
May bind repeated elements in single-stranded DNA and may participate in transcriptional and translational gene regulation.
What are the official names of this protein?
Transcriptional activator protein Pur-beta-A, Purine-rich element-binding protein B-A.
What is the protein family that this protein belongs to?
Belongs to the PUR DNA-binding protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIP26_ORYSJ
Sequence: MSKEVSEEPEHVRPKDYTDPPPAPLFDVGELRLWSFYRALIAEFIATLLFLYITVATVIGYKVQSSADQCGGVGTLGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLLLARKVSVIRAVMYIVAQCLGGIVGVGIVKGIMKHQYNANGGGANMVASGYSTGTALGAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSIGAAVIYNQKKAWDDHWIFWAGPFIGALAAAAYHQYILRAAAIKALGSFRSNPSN
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin PIP2-6, OsPIP2;6, Plasma membrane intrinsic protein 2-6.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HFQ_SALTY
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs (By similarity).  Plays a central regulatory role in the microbial response to space flight conditions.  Is essential for virulence and is required for efficient invasion of non-phagocytic cells.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: G6PI_BACAN
Sequence: MSTHVTFDYSKALSFIGEHEITYLRDAVKVTHHAIHEKTGAGNDFLGWVDLPLQYDKEEFARIQKCAEKIKNDSDILLVVGIGGSYLGARAAIEMLNHSFYNTLSKEQRKTPQVLFVGQNISSTYMKDLMDVLEGKDFSINVISKSGTTTEPALAFRIFRKLLEEKYGKEEARKRIYATTDKARGALKTLADNEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGLNIEEMMKGAAAGRDDFGTSELEENPAYQYAVVRNALYNKGKTIEMLINYEPALQYFAEWWKQLFGESEGKDQKGIFPSSANFSTDLHSLGQYVQEGRRDLFETVLKVGKSTHELTIESEENDLDGLNYLAGETVDFVNTKAYEGTLLAHSDGGVPNLIVNIPELNEYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGFEELKAELEERLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_STRZP
Sequence: MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPS_YERPY
Sequence: MSTAKLVKTKPSELLYTRNDVEEHVKVATIKRLNQMVIQFIDLSLITKQAHWNMRGANFVAVHEMLDGFRTALTDHLDTFAERAVQLGGVALGTAQVINDKTPLKSYPTNIHSVQEHLKALAERYAIVANDIRKAITEVEDENSADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_PHOLL
Sequence: MKKNLLKSLYFQVLLAITIGILLGHFYPELGTEMKPLGDGFVKLIKMVIAPVIFCTVVTGIAGMESMKAVGKTGAIALVYFEIVSTIALIIGLIVVNVMQPGAGMNIDPSTLDVKAVSLYAEKAAEQGIIAFLLDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGEKGKPIFNIIDGFSHVIFGIINMIMRLAPLGAFGAMAFTIGKYGIGTLVQLGQLIVCFYITCILFVIFVLGTIAKATGFSIFRFINYIKEELLIVLGTSSSESALPRMLDKMEKAGCQKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTHMDIVHQITLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPLAGLALILGIDRFMSEARALTNLIGNGVATIVVAKRCRQLDEGKLNEVLNAK
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_ANAPZ
Sequence: MTEGRKPHINVGTIGHVDHGKTTLTAALTTVLARKLSGANKVVKYDEIDKAPEEKARGITISTAHVEYETEGRHYAHVDCPGHADYIKNMITGAAQMDVAILVVSATDGAMPQTREHILLAKQVGVKDIVVWINKCDVVEDEEMLSLVDMEIRELLSQYGYDGDSIDAVRGSAVKALEEDADGPWSDKIMELVGALEKIELPMREKDKPFLMSVEDVFSIPGRGTVVTGRIERGVVRVGDKIDIVGLRELQSTVCTGVEMFHKALEAGEAGDNAGILLRGIKKEDVERGQVLSAPGQMKSYKKFKAEVYVLKKEEGGRHTPFFANYQPQFYVRTTDVTGSISLPAGVEMVMPGDNLSIEVALDKPVAIDKGLRFAVREGGRTVGSGIITEILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_STRS2
Sequence: MFVKKGDKVRVIAGKDKGVEAVVVTALPKVNKVIVEGVNIVKKHQKSNSENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: FRDC_ECO27
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.