PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_I80AC
Sequence: MASQGTKRSYEQMETGGERQNANEIRASVGRMVGGIGRFYIQMCTELKLSDNEGRLIQNSITIERMVLSAFDERRNKYLEEHPSTGRDPKKTGGPIYRRRDGKWVRELVLYDKEELRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRAHVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGVNDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGAVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVLPRGQLSTRGVQIASNENMETMNSSTLELRSKYWAIRTRSGGNTNQQRASAGQVSVQPTFSVQRNLPFERATIMAAFTGNPEGRTSDMRTEIIRMMENSRPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: CHS6_PEA
Sequence: MVSVSEIRKAQRAEGPATILAIGTATPANCVEQSTYPDFYFKITNSEHKTVLKEKFQRMCDKSMIKRRYMYLTEEILKENPSLCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPLPEIEKPIFEMVWTAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNINKALVEAFQPLNIDDYNSIFWIAHPGGPAILDQVEEKLGLKPEKMKATREVLSEYGNMSSACVLFILDEMRKKSAQQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 6, Naregenin-chalcone synthase 6.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RL2_STRZJ
Sequence: MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: THIG_RUEPO
Sequence: MRAFYGTELPNPLMLGTAQYPSPAILEQAFRASGAGVATVSLRRESGAGQTFWSMIRDLGVLILPNTAGCHTVKEAVTTAHMAREVFGTPWIKLELIGHTDSLQPDVFGLIEAARILTEDGFQVFPYTTDDLIVGERLLAAGCEVLMPWGAPIGSGRGLNNEYALRAMRAEFPDTPLVVDAGIGLPSHAARALELGYDAVLLNTAVARAGDPVEMARAMALAIQAGQLAHRADPIEARDMASASTPVIGKAFLS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NR5A2_MOUSE
Sequence: MSASLDTGDFQEFLKHGLTAIASAPGSETRHSPKREEQLREKRAGLPDRHRRPIPARSRLVMLPKVETEAPGLVRSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCIDVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTSAIQNIHSASKGLPLSHVALPPTDYDRSPFVTSPISMTMPPHSSLHGYQPYGHFPSRAIKSEYPDPYSSSPESMMGYSYMDGYQTNSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQSNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSTIISHTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENLQLVEGVQEQVNAALLDYTVCNYPQQTEKFGQLLLRLPEIRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHAKRA
What is the function of this protein?
Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis.  Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism.  Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.  Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver.  May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity).  Activates the transcription of CYP2C38 (PubMed:30555544).
What are the official names of this protein?
Nuclear receptor subfamily 5 group A member 2, Liver receptor homolog 1, LRH-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_STRMK
Sequence: MSDKATDIANLLAPTVVSLGLELLGVEYLPAPGGATLRLYIDVPLAEQPERIINVDDCERVSREVSAQLDVEDPISGNYTLEVSSPGVDRPLFNLEQFARHQGESAKVTLKLPQDNRRRLQGRIEATDEAAGTITFIVDKTEVVVSADNIDKARIMPDWVALGLAPSKPTGPAPKRPKPNTNSSSNEPAAKKPRAE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_PSEE4
Sequence: MAVQRTFSIIKPDAVAKNVIGKITTRFEEAGLKIVASKIKQLSKAEAEGFYAEHSARGFFGDLVAFMTSGPVVVQVLEGENAIALNRELMGATNPKEAAPGTIRADFAESIDANAVHGSDSEAAAAREIAYFFAATEVTTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUS_ECO45
Sequence: MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNFSQAALVSHIQHINKLKTTFEHIVTVESELPSAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_STRA1
Sequence: MVKGQGNVVAQNKKAHHDYTIVETIEAGIVLTGTEIKSVRAARITLKDGYAQIKNGEAWLINVHITPYDQGNIWNQDPDRTRKLLLKKREIEKISNELKGTGMTLVPLKVYLKDGFAKVLLGLAKGKHDYDKRESIKRREQNRDIARQLKNYNSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: THIM_AGRFC
Sequence: MSGDFPTAARAAEILERVRQMRPRVHCLMNTVVQKFTADGITVIGGIPSMTTSLEEIESFVTKADALTVNLGTLDAERRRVIRLAIEIANASGKPWIVDPVHVDYSPSRLDFARELIAQSPTIVRGNRAEMSLIGDVPDVVRIETGPVDHLRDRTRNVSIVNGHPWMAKVTGTGCLSGGVIAAFMAVEKDALTAAASALAVTGVSAELAAQRAKGPGTFEPAFLDALSEISGEDIINHARIEHEQG
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Probable hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: HBB_POTCF
Sequence: GKLTDSQEDYIRHVWDDVNRKLITAKALERVNLVAEALSSNYH
What is the function of this protein?
Shows antimicrobial activity against M. luteus (MIC=4 uM) and E. coli (MIC=12 uM), as well as against the yeast C. tropicalis (MIC=4 uM) (PubMed:22683678).  Shows a pro-inflammatory effect, since the topical application of the protein induces an increase of cellular recruitment characterized by an increase in the number of leukocyte rolling (PubMed:22683678).  Does not show hemolytic activity on human erythrocytes (at doses up to 100 uM) (PubMed:22683678).
What are the official names of this protein?
Antimicrobial protein PcfHb.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in cutaneous mucus.
Protein: ARNT2_DANRE
Sequence: MATPAAVNPSEMGTDLPGPVSMPGAVVGAGQVRMTGAMPGRGGKRRSAGMDFDDEDGEGPSKFSRYDDDQIPGDKERYARENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNTSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNHPQSEWFGSTLFEQVHPDDVDKLREQLSTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSAPLDHISLNRLSSMRKRYRNGLGPSKEGEAQYSVVHCTGYIKAWPPAGMTIPDEDTEAGQTSKYCLVAIGRLQVTSSPVSMDMNGLSVPTEFLSRHNSDGIITFVDPRCINVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRMKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQQAELEVHQRDGLTAYDLSQVPVSGVSAGVHESGKTIDKTESLFSQERDPRFSDIYTGISTSEKKMMVPSSTSGGQQLYSQGSPFQPGHSGKSFSSSVIHVPGVNDIQSTAGSAGQNLSQISRQINTGQVSWSGNRPPFSGQQIPAQSNKAQSSPFGIGSSHSYQADPSSYSPLSSPATSSPSGNAYSNLANRNTAFDVSGESSQSGGQFQGRPSEVWSQWQSQHHSQQAGDPHPHTQASQTEVFQDMLPMPGDPTQGTTNYNIEDFADLGMFPPFSE
What is the function of this protein?
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis.  Specifically recognizes the xenobiotic response element (XRE) (By similarity).  Isoform 1 acts as a transcriptional activator (PubMed:11072074).  Isoform 3 acts as a transcriptional repressor (PubMed:10960127, PubMed:11072074).
What are the official names of this protein?
Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, zfARNT2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAD_HORVU
Sequence: MAMATQASAATRHLITAAWSPSAKPRPATLAMPSSARGPAPLFAAAPDTPAPAAPPAEPAPAGFVPPQLDPSTPSPIFGGSTGGLLRKAQVEEFYVITWTSPKEQVFEMPTGGAAIMREGPNLLKLARKEQCLALGNRLRSKYKIAYQFYRVFPNGEVQYLHPKDGVYPEKVNAGRQGVGQNFRSIGKNVSPIEVKFTGKNSFDI
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein.
What are the official names of this protein?
Photosystem I reaction center subunit II, chloroplastic, Photosystem I 20 kDa subunit, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FUMC_THEVB
Sequence: MTTDTRLEYDSLGAVEVPADCYWGAQTARSLKHFAIGSQRMPLAVIHAMARLKKAAAIANRDLGVLDPEKAKWIIQAADEVIAGQWDDQFPLAIWQTGSGTQTNMNVNEVIANRAIELAGGVKGSKSPIHPNDHVNCSQSSNDTFPTAMHVATVLALQERLLPTLRHLLTVLQEKAAAFAEIIKIGRTHLMDAVPLTLGQEFSGYASQIAAAQAHIEYALQHLYPLAIGATAVGTGLNAPAGFGDRVAAELAQMTGYPFRKAENPFAALAAHDPLVMLSGALKTLAAALMKIANDIRWLGSGPRCGLGELRLPANEPGSSIMPGKVNPTQCEALTMVCVQVMGNDAAVGIAGSQGNFELNVYKPLIIYNVLQSIALLSDAAQSFTDHCLVGVEPNRQQIQAYVERSLMLVTALNPHIGYDKAAAVAKKAYSEGKTLKEAAVELGYLTAEEFDRWVRLELMLGEKGTS
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A2A_MOUSE
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 2-A, H2a-614, H2a-615, Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ORC2_SCHPO
Sequence: MLINEHVRERYHFLRVSLTRVAHLVFANSHESNDLKMVENVSSTPKKGVLEDPSTLTPEVVTPRTPGHRIIKAKGAYTKDRSAKRRRGRIEIERHLLGEFDDNVGSNSLLDVPLYSLEAEPLSPSVMLEDESMEGINQSPQGISVEKLGKEDNRSRSSTPASPSLESHEFSESREAGLSQSNGFEARSHGTGFDEYFDKFSQRKTSSNTLSQLPVLDNQVYLDTVKEICTETEQHTQTLVHFQSRNFHQWYFELVNNFNLLFYGFGSKEHFLSSFVEKKLPCFPIFVVKGYFPQLQLKNVLSSFLEFLEVTPAASVSDMLIQSLSIINSPSFSLGKIVFLVHNIDGESLIDERFQSALAAIASSKNVYFIASVDHVNFALLWDTSLESSFNFVMHDATTFARYYNETTYENSLGIGRANVSNKEKAIKHVLYSLPANSRGIFKFLLIHQLERMMDTQDFDARQGEKVGIEYRSFFQKCSAEFLCSNEPNFRSQLTEFFDHNIIESKRDVSNSEILWVPYPKNLLEILLEDMMEDV
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication (PubMed:11850415).  It has a role in both chromosomal replication and mating type transcriptional silencing (PubMed:11850415).  ORC binds to multiple sites within the ars1 origin of DNA replication in an ATP-independent manner (PubMed:11850415).  Together with cdc18, plays a role in preventing DNA rereplication and resulting genetic instability upon cell cycle-regulated phosphorylation by cdc2 (PubMed:11486016).
What are the official names of this protein?
Origin recognition complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the ORC2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ASCL1_XENLA
Sequence: MDNCVAAKIMDSNLSSQQQHFLQPHCFFPQNVQQLSPAEEQQASKAKPIKRQRSASPELMRCKRRLNFNGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISPNYSHDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTTWF
What is the function of this protein?
Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways (By similarity).  Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes (PubMed:8443105).  The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro (By similarity).
What are the official names of this protein?
Achaete-scute homolog 1, XASH1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSB_PELPB
Sequence: MKAVILIPARLDSSRLDRKMLADLEGEPLIVRTWRQALKSRLAEKVVVATDSREIAAVLDACGAEVVMTSPTASCGTERIAEAARHIEGDVFVNLQGDEPLISPENIDLALEPFFSENPPDCSTLVLPLRPDDHVQIEDPHQVKVVMDAKGFALYFSRSAIPFQRNMRPTTIVYRHIGLYAFSADVLQKFASLPPSMLEEAESLEQLRLLENGFRIQCVTTLVDNPGVNTVEDLEQVRRIIRSSLPG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRP_BACSU
Sequence: MSKKKVNLGVRDVPTPFSWVSFSLQHLFAMFGSTILVPKLVGMSPAVALVTSGIGTLAYLLITKGQIPAYLGSSFAFISPIILVKATGGPGAAMVGAFLAGLVYGLIALLIRQLGTGWLMKILPPVVVGPVIIVIGLGLASTAVNMAMYADPNASELVYSLKHFSVAGVTLAITIICAIFLRGFLSLIPVLIGIIGGYLFALTQGIVNFQPVLDAKWFAVPEFIIPFKDYSPSVTLGIAAAMVPVAFVTMSEHIGHQMVLSKVVGQDFIKKPGLHRSIMGDSVATILASLIGGPPTTTYGENIGVLAITRVFSVFVIGGAAVIALCFGFIGKISALISSVPSAVMGGVSFLLFGIIASSGLRMLIDNKIDYENNRNLIITSVILVIGVGGAFIQVSQGGFQVSGMALAAIVGVILNLILPQAKEEQADTSEQHHI
What is the function of this protein?
Transport of uracil in the cell.
What are the official names of this protein?
Uracil permease, Uracil transporter.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_MYCVP
Sequence: MRPLAIVGPTGTGKSDLALAVAGLLSAEIAVEVVNADAMQLYRGMDIGTAKLTVVERHGVPHHQLDVLDVTETATVARYQQAAAADVEAIAARGALPVIVGGSMLYVQSLLDQWSFPATDPRVRTRWERRLAEIGVAALHHELADVDAAAAASILPTDGRRIVRALEVVELTGQPFAASAPTIGAPRWGTVIVGLDWDTTVLDERLARRTDLMFERGLVDEVVGLLGVGLREGVTAARALGYAQVLADLDAGGDGSAAREPTFVGTRRYVRRQRSWFRRDHRITWLDGAAGGSAALADKVIRIWRDVS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ARAF_PIG
Sequence: MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSVQDLSGGSRQHETPSNRPLNEPLTPQGPSSCTQHRDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSGLVQLTAQSFNTDAAGNRGGGDGAPRGSPSPASVSSGRKSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
What is the function of this protein?
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.  May also regulate the TOR signaling cascade (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase A-Raf, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: MATK_QUERO
Sequence: MEEFQGYLELDIFRQHDFLYPLIFREYSXXXAHGHGLNRYMLLENIGYDNKSSLLIVKRLITTMYQQNYLIISANDSKQNPFFGYNKNLHSKILSEGFAIIVEIPFYLRLISSLEGAEIVRFYNLRSIHSIFPFLEEKFPHLNYSADILIPYPAHLEILVQTLRYRVKDASYLHLLRFFLHEYSNCNSLIITNKSISIFSKSNPRFFLFLYNSYICEYESIFLFLRNQSSHLRLTSSGVLFERLCLYRKIEHFAEVFANDFPVIPCFLKDPFMHYVRYQGKSILASKDTPLLMNKWKSYLVNLWQCHFDVWSHAASIRINQLSKHSLDFLSYFSSVRRNPAVVRNQMLENSFLLNNAPNKLDTIVPIIPLIGSLAKAKFCNAVGHPISKLTRADLSDFEIINRFLHICRNLSHYYSGSSKKKNMYRIKYILRLSCVKTLARKHKSTARAFLKRVDSEFFQEFFTEEGGFISLIFPRASFALRRLYSGRVWYLDIIFINGLSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: XKDG_BACSU
Sequence: MRNQEIIRKAEMSLSALKSGGLMNPAQASAFIRMVQNTPTIFSESRVIQMENDSQKFEKIGFGQRILRAAQEGKALSNDELTVPTTSTVQLNTKEVIAEINITYDTLENNIEKDGLQQTIMQILAERAAVDIEELIVNGDTASADPYLAQLDGIRKQAVSHIVDMNGEELSRATFKKGLKAVPPKYLRIPQEFRFYTSHGLEVEWKDRVADRQTNLGDQAVQGGLSTAFGVPVKGVSNIQPYTVGEGDAQYDASDIILTHPKNIILGFSRNIRIEVDKDIRSRKFIIVLTAKLDSKFEEEDACAKLINVKE
What is the function of this protein?
Possibly a prophage capsid protein.
What are the official names of this protein?
Putative prophage capsid protein XkdG, Phage-like element PBSX protein XkdG.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_ECO55
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MTH2_HAEPA
Sequence: MKDVLDDNLLEEPAAQYSLFEPESNPNLREKFTFIDLFAGIGGFRIAMQNLGGKCIFSSEWDEQAQKTYEANFGDLPYGDITLEETKAFIPEKFDILCAGFPCQAFSIAGKRGGFEDTRGTLFFDVAEIIRRHQPKAFFLENVKGLKNHDKGRTLKTILNVLREDLGYFVPEPAIVNAKNFGVPQNRERIYIVGFHKSTGVNSFSYPEPLDKIVTFADIREEKTVPTKYYLSTQYIDTLRKHKERHESKGNGFGYEIIPDDGIANAIVVGGMGRERNLVIDHRITDFTPTTNIKGEVNREGIRKMTPREWARLQGFPDSYVIPVSDASAYKQFGNSVAVPAIQATGKKILEKLGNLYD
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-CCGG-3', methylates C-2 on both strands, and protects the DNA from cleavage by the HpaII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HpaII, M.HpaII, Cytosine-specific methyltransferase HpaII, Modification methylase HpaII.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.