PharMolix/UniProtQA huggingface dataset:
Protein: ALL2_ASPFL
Sequence: FDKNQPWGVIRDLNVVNFKR
What are the official names of this protein?
Allergen Asp fl 2, Allergen Asp l 2.
Protein: TRUB_CHLTR
Sequence: MELATESIEGVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLFEDKEYAAVAHLGTTTDTYDCDGKIVGRSKKVPTMDEVLTCTSYFQGEIQQVPPMFSAKKVQGKKLYEYARQGLSIERRFATVTVNLRLVKYEYPRLHFVVQCSKGTYIRSIAHELGNMLGCGAYLEELRRLRSGSFSIDQCIDGNLLDEPGFDVSPYLRDANGLILQPAPVL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MATK_TRICT
Sequence: MEELQLQGYLEKDGSRQQNFLYPLIFQEYIYTLAHDHGLNSSIFYEPMEIVGLGYDNKSSSVLVKRLITRMYQQNSLIYSMNDFNQNRFVGHNNSFYSNFDSQMVSEGFAVIVEIPFSLRLVPSSEEIQIPKSQNLRSIHSIFPFLEDKLSHLNYVLDILIPYPIHLEILVQILQCWIQDVPSLHFLRFFLHEFHNWNNLNLITPTKSISVFSKENKRLFWILYNSYVSEYEFLFVFLRKQSYYLRSTSSRAFLERTHFYVKIEHLIDVCHNHFQKILWFFKDSFMHYVRYKGKAILASRGTYLLIKKWKCYLVNFWQYNFHFWSKPYRIHINPFSNYSFYFLGYISSVLINPSAVKNQMLENFYLVDTLTQKFDTIVPVIPLIGSLSKAKFCTILGHPISKPIWAELSDSDIMDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRNLLQRLGSGLLEEFFTEEEQVISPIFPKTTLFPLHGSHRERIWYLDIIRINDLANYLDWS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KAD_LEPBJ
Sequence: MKNIIFMGPPGAGKGTQAKILCARLSIPQISTGDILREAVKNQTPMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGTLEEVTSLIQRELV
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRIY_LYMST
Sequence: MNSVLFLTLAVCSSLAYGKEFVATVRQNYKENINQLLEQQIQKELAASYIYQAYASYFQRADVSLPGIKKFFSDASSEERDDAQSLIDYINQRGGHVQYDKIDLKDACETVMKFVTSDTSGLEEFRDRRMCICGFVATKTINDNCGERSDWKEGLIAFEDTLAIERYVNAQLLDIHKKADDEKDAHLTHILEHEFLEEQVSSINKIAHAITRLRSFEQGSGNNYKLGRVYLRPTPQISH
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Yolk ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IORB_METTM
Sequence: MSYNIYVCGVGGQGIIKTSVIIGEAAMNEGMNVVMSEIHGMAQRGGAVSTEIRFGDVRGSIIPQGEADLVIAFEPLEALRALPKMSEDACVIVNTSKIPPFNLIKSPHPYPPLEEIIKTLEENAGRVRSFNGEKIAVEAGHILSLNMVMLGAAAATTGFPLGEETLIESMKNNLPPKLMEVNLRAFHEGFETVNCD
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorB, IOR, Indolepyruvate ferredoxin oxidoreductase subunit beta.
Protein: SYS_PSELT
Sequence: MIDIRLIREKPDFVKKALEKRNYEKKMVDDLLSLDAQFRELTNQINQLRAQRNSISKMVAQAKSSGKTEEIENLTEEGKKIGRQIDSIEDQLKEIKVQMEKLMLLVPNIPDDSVPEGKDETSNREIRKWGDPKKFDYNPQAHWDLGPSLGLMDFDRAAKLSGSRFTVMYGMFAKLERALTNFMLDMHTKEHGYTEVWLPHIVKRETMTITGQLPKFEEEAYRIEADDLFLIPTAEVPLVALRSNEILEEKDLPLLYTAYTPCYRREAGSYGKDVRGMIRQHQFDKVELVWITTPERSFEDLETLVSHAEEVLRRLELPYRVIQLCSGDLGFGAAKTYDLEVWLPSYNSYKEISSCSNDTDFQARRGNIRYRRKDGKISFVHTLNGSGVAVGRTLVAIIENYQRADGRIDVPKALQPYLGCEVLG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_CLOK5
Sequence: MNDLKLDKVSKVLKEVRKSVPLVHCITNYVTINDCANILLSYGASPAMCEAYDEVFDFVKISSALYINIGTFTREQESSAILAAVSAKTHNIPVVLDPVACAAIPKKIQFIDKLFKVGRVDVIKGNIGEIKFLAGETSNVKGVDSLEDGEGALECSRILSEKYNCVVAATGKKDFIVQGKNSAIIENGTEMLTNITGAGCMLGALCAAACGAFEDKFMAVVGAILSINIASEEAYKEAKAPGSFRVKLIDCIYELSEEKLKKEGKIAWN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RPOA_WHEAT
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGASFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HBG1_HUMAN
Sequence: MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYE_PSEP1
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGIEWNEGPDVGGPHGPYRQSERGEIYAKYAKELVDAGHAFYCFCTAEELEQMRAEQQARGETPRYDGRALLLSAEEVQRRLDAGEPHVIRMKVPSEGICVVPDMLRGDVEIPWDRMDMQVLMKNDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQPKLCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLAEMVEHFDLSRISLGGPIFDIEKLSWLNGQWLRELPVEEFAARLQKWAFNSDYMMKIAPHVQGRVETFSQVAPLGGFFFEGALKLDAKLFESKKLSADQVRQVIQLILWKLESLRQWEKERITGCIQAVVEALELKLRDAMPLMFAAITGQASSVSVLDAMEILGPDLTRYRLRQALDLLGGVSKKENKEWEKLLASIG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_METKA
Sequence: MPGKKSPAGEFAARKLREKRKKFRWKDERYKRRMLKLDEKADPLEGAPQARGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKQVTAFCPGDGAIDYIDEHDEVVIEGIGGPKGRAKGDIPGVRYKVVKVNDVALSELLKGKIEKPMR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PCKA_AMOA5
Sequence: MHVLSNPKHVTWLTQMGLDQIGEAYWQLGVPELVEHAIHNSEGVLSAEGALVCSTGKFTGRSPQDKFIVEDEKTRDTIWWGPVNNPFDSKQFDALYEKVTQFLQGKRVYIRDGYASALPEYKLNLRTVTTQSWTNLFVNNLFLRPIDKELTKFSPDFLILQVPEFQADPHVDGTKNANFTIINFTKRVILIGGTGFAGEIKKAVFTVLNYLLPQEHQVLPMHCSANVGTDGNTAIYFGLSGTGKTTLSADPNRKLIGDDEHGWCDKGIFNFEGGCYAKTINLAKESEPQIFDAIKFGTIVENMRFFAGTRTIDYKDSSITENVRCAYPLEYIPGALIPSIGSIPKHIFFLSCDAYGVLPPISQLDKDQAIHYFLSGYTAKIAGTEAGISAPKAVFSACFGAPFLPLHPTRYATMLADKLEKYEVTVWLVNTGWIGGGYGIGKRIDLNYTRAMVTAALSGELAKAGFEKDAIFNLSIPNACPEVPTHILNPSNTWNSVKEYELEAHKLMEAFASNFALYCD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ENT38
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLNATHGYELTELAEEADVLLLNTCSIREKAQEKVFHLLGRWKLLKKKNPDLIIGVGGCVASQEGKLIRTRSPYVDIVFGPQTLHRLPEMINSVRGDRSPVVDVSFPEIEKFDRLPEPRADGPSAFVSIMEGCNKYCTYCVVPYTRGEEVSRPCDDILFEVAQLAAQGVREVNLLGQNVNAWRGENYDGSIGTFAELLRLVAAIDGIDRVRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQCGSDRVLNLMGRTHTVLEYKAIIRKLREARPDIQISSDFIVGFPGETTDDFERTMKLIGEINFDVSFSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQVTAWSRRMLGTTQRILVEGTSRKSVMQLSGRTENNRVVNFEGTPDMIGKFVDIEILEVLTNSMRGKVVRTEDQMGLRVAETPASVIARTRKENDSGAVVYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTD_VIRSA
Sequence: MEDLYPSRQNNQPKILKRKDPVIYTDRSKDNQAPITKEQLDSYEKNGFLQIKNFFSEDEVIDMQKAIFELQDSIKDVASDKVIREPESNDIRSIFHVHQDDNYFQDVANDKRILDIVRHLLGSDVYVHQSRINYKPGFKGKEFDWHSDFETWHVEDGMPRMRAISVSIALSDNYSFNGPLMLIPGSHNYFVSCVGETPDNNYKESLKKQKLGVPDEESLRELTRIGGGISVPTGKAGSVTLFESNTMHGSTSNITPYPRNNLFMVYNSVKNRLVEPFSGGEKRPEYIAVREKQPVYSAVN
What is the function of this protein?
Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte.  Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.
What are the official names of this protein?
Ectoine dioxygenase, Ectoine hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. EctD subfamily.
Protein: U496E_ORYSI
Sequence: MGNRHGIMRPRRLASGRSAAAAEEEGEDGEGEPGSYEAACSADPELGTFDTALRRRASRAITAVASGVEVRSLSLGSLREVTGCLLDMNQEVVRVVLACKRDVWRSPDLFDLVEDYFEGSLHTLDFLAALDKSLHRARDSQLVLHLAVQRHHHEPPAAAAASASELYASTLGELRQFKAAGEPFTDEFFAAFQTVYRQQMSMVGKLRRRKRRLDRRLRSVRVWRRVSGIVFLTAFAALLVCSVVAAAIAAPPVAAALAPAASMPVGSAGKWMDSLLKKYQDALHGHKEVVSAMQVGTFIAIKDLDSIRVLVEHLEVQISSMADSVEFAERDEEAVRFGIDEVKKKLELFMKSVDDLGEQADRNNMRLCHILPEYVFFINPANGNGMSESLFEMMNAFHDICRKDIKFKTSHYYLNFLSSSYQVYIAVA
What are the official names of this protein?
Putative UPF0496 protein 5.
What is the protein family that this protein belongs to?
Belongs to the UPF0496 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YL060_MIMIV
Sequence: MELKINDLCDDVIVNIFEYLSDNDKMNFMFTNRYFSYLIDKTFYNDVHHYRLVHNLPFYNKFKKIEYYASTNNIPNGITHLVFNDEFNDNVDGRIPCSVKCLTFGKSFKKPLKPGTIPFGVEKIIFKSWYNKSISGGIIPGSVIHLEFKTSRKLSKGDIPENIRHLELICNNQSLGVIIPRNVKYLKIGYNILLNETTLPYGLTHLVFDYNFNGKINGFIPETVTHLEFGNKFNQPLEIDDIPSNVVYLKFGTDFNQPITSKVIPSSVKHLEFGYYFNQPINRGVLPQGLISLTLSCKFNQILEPGVIPDTVKILNIYPSNVCPISIGVIPSRLTHLNIVQELNQILDQTILPETLTYLRIPHCYNHPIKPGIIPLSVTELEFGSNYNQVLEIGTIPPNVNSVTFGTKFNQPLSKGVIPNSVKKIRFGFEFNQLLKVGDIPYGVTHLYLGNRFNQPLEIGVIPESVTHLDLGYCFKQPLEIGMIPSSVTNIKFSMYYYLPIKRGVIPDRVKHLNLNYIYTGCDPDFIPKSVTHLQFDLGYNFRLIDFKIPESVIDLEISRAYYPIGPKIIPNSVQKLSIWDYKGEVTDDIVGKNVVCLRVSPLNYRGYEKYLDLGIEFKTY
What are the official names of this protein?
Putative F-box and FNIP repeat-containing protein L60.
Protein: YCAR_SHIDS
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MURC_COLP3
Sequence: MIKQTHVSNSSNNSTNSTAAQVPEMRRVKRIHFVGIGGAGMGGIAEVLLNEGYQISGSDIGENQVVKRLRALGATIVIGHQAENVVQASVIVVSTAINSENPELVKAKELRIPVVRRAEMLAELMRFRHGIAIAGTHGKTTTTSLIASIFAQGKLDPTFVIGGLLNSAGTNARLGSSRYLVAEADESDASFLHLQPMVSVITNIDADHMETYQGDFEKLKDTYIEFLHNLPFYGLAVVCIDNPVVRELLPRISRQVITYGFSKDADVRAVNYQQNGAVSHFTVEVEGQEPLEMSVNLPGQHNVLNALAGVAVAKDEGVNDEAICKALTEFEGIGRRFEKLTDFSTAAGDMVLVDDYGHHPSEVKATILAMRQGWPDKRLVMVFQPHRYSRTRDLYEDFVEVLSEVDCLFLLDVYAAGETPISSADSKSLARSIRLRGQIEPVYVSDVDKLPQLLATQLQDNDMVITQGAGSIGAVARNLADHSLLHTRCSVQPDAQSEVKGDK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_SALTY
Sequence: MNIDLNADLGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCVREALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRHVKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVFADRGYQADGSLVPRMQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVIA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: KIF23_MOUSE
Sequence: MKSAKAKTVRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNSMEIQCEVDALLERQKREALPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKLPQSKTLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQTYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARPVDKVICGLTPGRRYRNLPRGGPVGDEPLVPEVILQSFPPLPPCKLLDINDEETLPKLADTLEKRHHLRQLMTEDLNKKCLAFKALLKEFDNSLSNKENYVQEKLNEREKVISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQNQKLQRQFSDKRRLEARLQGMVTETSMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPEKPERPSRERDREKIIPRSVSPSPLPLSSNNIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKTCIVSDRRRGMCWTEGREMVPTFSSEIGVEEDHCRRNTPIPVRHRRSRSAGSRWVDHKPASNVQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQELPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP
What is the function of this protein?
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis.  Essential for cytokinesis in Rho-mediated signaling.  Required for the localization of ECT2 to the central spindle.  Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF23.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles (By similarity). Detected at the midbody during later stages of mitotic cytokinesis.
Protein: RNZ_LACP7
Sequence: MLDVCLLGTSGMMPLPGRWLTALMTRLNGSSLLIDCGEGTQIAIREKGWSFHSIDIICFTHYHGDHISGLPGLLLSMGNADRTQPVTVIGPKGLERVVSALRVIAPELPFELNFIEVTNPQETICVNDYVINAFRVNHNVICYGYTIEVKRTGRFIPEMAMQNEVPIELWSRLQKGQTIEKDSRVFTPDMILGPQRKGIKLTYCTDSRPVPQIIEQAQGSDLFICEGMYGEKEKQSNAIENKHMTFYEAAELAKQAGVKELWLTHYSPSLTRPEEYMKETKEIFPNAKAGKDRKSITLEFDKNE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: EPN2_ARATH
Sequence: MKKVFGQTVRDLKREVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAEVRQKAAANRDKYRSSAPGGMYKPSGGYGDKYDYGSRDEERSSYGREREYGYRDDDRNSRDGDRHSRDSEDRYGRDGNRDDDYRGRSRSVDNYGSRGRSSEREREDDGHSSSRGSGARADDNSQDGRGGLQRKFSEQNIGAPPSYEEAVSDSRSPVYSERDGGETPQVTAPGAASPPPPQVAAPEAASPPTGTNTANTTATFVNESPSQKVETFDEFDPRSAFSAGPPAYASTDGVTAPPTVTSMSAPTTSNSVEMDLLGSLADVFSSNALAIVPADSIYVETNGQANAGPAPSFSTSQPSTQSFDDPFGDSPFKAFTSTDTDSTPQQNFGASFQPPPPAFTSEVSHPDTAHNFGFGDSFSAVANPDPASQNVQPPSNSPGFPQEQFATSQSGIDILAGILPPSGPPVQSGPSIPTSQFPPSGNNMYEGFHSQPPVSTAPNLPGQTPFGQAVQPYNMVPHSQNMTGAMPFNSGGFMHQPGSQTPYSTPSGPAGQFMAHQGHGMPPSHGPQRTQSGPVTLQGNNNVMGDMFSQATPNSLTSSSSHPDLTPLTGAIEIVPPPQKKFEPKSSVWADTLSRGLVNFNISGSKTNPLADIGVDFEAINRREKRLEKQTNTPATSTINMGKAMGSGTGLGRSGATAMRPPPNPMTGSGMPMGGGMGVGSYGGMNQNQPMGMGMGAGMNQNQPMGMGMGPGMNMNMNMGGYGQGYPMQPQNPGMVPSPNMPGNNYNPMMGQGGYNPQQSYGGGYR
What is the function of this protein?
May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes.  Stimulates clathrin assembly (By similarity).  Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3)P).  Plays an important role in protein trafficking.
What are the official names of this protein?
Clathrin interactor EPSIN 2, EPSIN-related 2.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Localizes also to a novel cellular compartment, the 'delta compartment', characterized by colocalization of EPSIN2 and DELTA-ADR.
Protein: GLMM_STAAN
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NODO_HYPPI
Sequence: MEVSSSETLPILWRTSPPSNDYENARCRVFNGRQPEHFPLAIVKANKVEHIVAAVKLAAELDACIAVRSGGHSLSCWTIRHGAILIDLEDYQHLSYDDEIHEVQASPSTLGADLLTFLAKKKRFFPVGHSGDIGLGGYLLQGGIGLNSRGYGYACEYITGLDIITADGEIKHCDKTENSDLYWAARGAGPEFPAIVIRFFLKTCPLLPVCKRSRYVWPAAMYGKVFKWLEELLNSLSEDVEIAVFGFVLPRLNQPGLVLHATAFGDSSENVREKLTPIIKNHPPGTFLAEDFVSTNFPEDYDLGKDTMPRGARYFTDSVFLKPGIDFVATCKGMFTELKHPRALAYWQPMKTNIDRILPDMAMSIHSHHYVSLLAIYEDPSEDQQQISWIIDRMKSLEPAILGTFIGDAHPVERPSNYWSEEAEERVITIGRKWDPSSRIRGIVLSDA
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA).  Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthropods and lack of observable adverse effects on mammals, in particular the tremogenicity associated with the paspaline-derived IDTs is not observed (PubMed:29283570).  The geranylgeranyl diphosphate (GGPP) synthase ggs1, localized outside of the cluster, is proposed to catalyze the first step in nodulisporic acid biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:29283570).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase nodC then forms 3-geranylgeranylindole (3-GGI) (PubMed:29283570).  Epoxidation by the FAD-dependent monooxygenase nodM leads to a single-epoxidized-GGI that is substrate of the terpene cyclase nodB for cyclization to yield emindole SB (PubMed:29283570).  The terminal methyl carbon, C28, of emindole SB is then oxidized by the cytochrome P450 monooxygenase nodW to produce nodulisporic acid F (NAF), the pentacyclic core of NAA (PubMed:29283570).  NAF is converted to nodulisporic acid E (NAE) via prenylation.  This step is probably performed by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  Several oxidation steps performed by the FAD-linked oxidoreductase nodO and one of the cytochrome P450 monooxygenase nodR, nodX or nodZ further convert NAE to nodulisporic acid D (NAD) (Probable).  NAD is substrate of cytochrome P450 monooxygenase nodJ to produce the precursor of nodulisporic acid C (NAC), converted to NAC by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  The FAD-dependent monooxygenase nodY2 then oxidizes NAC to nodulisporic acid B (NAB) (Probable).  Finally NAB is converted to NAA by one of the cytochrome P450 monooxygenases nodR, nodX or nodZ (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase nodO, Nodulisporic acid biosynthesis cluster protein O.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: DISP2_HUMAN
Sequence: MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVIFLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNSSSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQADAARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDFLSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQELLRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRWEGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYIAGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLPVDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVETLQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSLAALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSLSTEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEALFLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPATVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPGGEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPLPASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDLDDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNSQPDLPDVWLRRPSTHTSGYSS
What are the official names of this protein?
Protein dispatched homolog 2.
What is the protein family that this protein belongs to?
Belongs to the dispatched family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.