PharMolix/UniProtQA huggingface dataset:
Protein: MECA_LEVBA
Sequence: MEMERINENTIRVVIGNDDLTERGITVLDLLGNHKQIEGFFYSILEEVDVDHQFQDNDAVTFQVLPNRNGLELFISKNTDEDDVADESQGDASVDSEHPDQVSDQIKEHLLEKDNQKDFFSGFKSAANESNDIEDYLNDSGQPTTTRVVKLHSFEDMISLARVLRLENAASNLYRYQDAYYLELVFFVNESSRESIKDELAVAYEYAERTKVAPDVLAEHGQLIMDNSALELTRFHFLGNS
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: ILVC_RHIEC
Sequence: MRVYYDRDADLNLIKAKKVAVIGYGSQGRAHALNLKDSGAQNLVIALKAGSPTVKKAEADGFKVMTVAEAAGWADLMMMATPDELQADIYKADIAPNIRDGAAIAFAHGLNVHFGLIEPKASVDVVMIAPKGPGHTVRGEYQKGGGVPCLVAVHQNASGNALELALSYACGVGGGRSGIIETNFREECETDLFGEQVVLCGGLVELIRAGFETLTEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITEETKAEMKRVLKDIQTGKFTSEWMQEYRSGAARFKGIRRNNDSHQIEEVGAKLRGMMPWIGKNKLVDKSVN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LPXD_ANAD2
Sequence: MASYTLAELAARVGGAVEGDGSLRLDGISPLEEASASEISFFSNRKYRKAFEASRAGAVVVEPDEQVAAGRTVLRVANAYLAFAKISTLFHPPREAVPEVAPTAVIHPTARVHPSAQVMPLACVGPDAQVGARTILFPGVHVADGARVGEDCVFYHNVVVRERCAVGNRVILQPGCVIGSDGFGFAFDPEGEGKGPRHYKVPQVGNVVIEDDVEVGANTCVDRATLGTTRIGRGAKIDNLVQIAHNVQVGPLSLLVSQVGVAGSTKLGMGVVAGGQAGIVGHLEIGDGVRIGAQSGVMADVEAGETVSGSPAVPHGNWLKAMASLDHLHDMRKELRSLRREVERLRADAGEDEP
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: NUOC_RHORT
Sequence: MTSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACRFSQLVDIAGVDYPSREERFEVVYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFEREAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGYKEVRYDEELKRVVYEPVRLSQDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: THII_CLOAB
Sequence: MNKLLMVKYASEIFLKGLNKNKFEKILKHNIATALNGVKFDFVFDSGRWFIKGEDLEEVVDRVRNVFGVAEVCIVTEIENDFDTIKNQALLAVKESGKGTFKVETNRANKGFPLNSMDINREVGAYILKNNDEVKVDIHNPECLVNIEIRKKTYIYSKRIKGVNGMPYKTNGQTLLMLSGGIDSPVAGYMMARRGVEVSGVYFHSAPYTSERAKDKVKDLARILTKYIGEMTLYVVPFTDIQMQIIEKCREDELTIIMRRFMMSIACKIAEDKGMESVATGESIGQVASQTMQGLVVSNDCADRPVFRPLISMDKIDIMDISRKIGTYETSILPYEDCCTIFVPKHPKTKPILGQIRKAESVLDKEKLINDAVEKMEVIQIKND
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4NF_SINFN
Sequence: MARYDARLRGIGKAHACSAFAGHDFEGRNIMKTPWKFLAQLASRRRSASVQENFIAPDTDPEVIESETENKSPLPFDKPTQASGTPDHDSAVDRGSMLSDQLESDPNPLQEMNLTADIQEPGTPARSETKQSDAAGKRLGPQSQTSANSQKKPEIRCRERSKNARAEGVAQSAVATNEAETVQTSSSGDPFFNEVAILDEEIKELRRLLAQKLYLQNAQLKKMLERFDAS
What are the official names of this protein?
Uncharacterized protein y4nF.
What is the protein family that this protein belongs to?
To R.meliloti RA0936 and y4aO.
Protein: CYB_CALMU
Sequence: MTIMRKNHPLLKIINNSFIDLPTPCNISSWWNFGSLLGICLMVQIITGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFIHVGRGIYYGSYMLSETWNIGIALFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDILGILMLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYSSLAYAILRSIPNKLGGVTALILSILILAMFPLINSSKLLGLVYRPITQAMYWIFIANLFILTWIGGQPVEYPFTMIGLISSILYFSIIVMFMFIASMIENNILKSH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TSK_XENTR
Sequence: MAPSWLFLLFIPGMVGSSRSCFPGCQCIVDNFGLFHSFSLTKVDCSGVGPHVVPVSIPLDTSYLDLSANGIKRINESVLSGPGYTTLINLNLSHNQIVRISFSTFSKLRYLESLDLSHNLLETLPDGSFLYSRLTELDLSSNKLLEVGIGAFTLKSQGRSMTINLGNNNIRSIHRGAERPVPNIHSLTLSGNDLLSVPDLHGIPLRHLDLDRNPLAKIEKESFLGLEGLTHLSLSDLPNLREVSPYSFKTLPSLLDLDLSSNPQLKSLSSDMFFGLDSLQELNLAYSGVAALPKDIMLNLPSMKSITWGENIRCSKTVKESPFHAQKGRVREEVLLCHDDYGAVPAQDVL
What is the function of this protein?
Contributes to various developmental events through its interactions with multiple signaling pathways.  Dorsalizing factor which functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation.  Promotes dll1-dependent activation of Notch signaling and is required for neural crest formation.  Induces endoderm and dorsal mesoderm formation by enhancing nodal2/Xnr2 activity while inhibiting ventrolateral mesoderm formation through inhibition of fgf8.
What are the official names of this protein?
Tsukushi, Leucine-rich repeat-containing protein 54.
What are the subcellular locations of this protein?
Secreted.
Protein: ISCA_ECOLI
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: MPH1_CANAL
Sequence: MIIFATPKVCKGKTRILYFYLSKLFFYVYFFFLIYYSIQKHSYINSTMPIIPLEDDKDDDWILEDEDDPEFQAILQGNSSKGPAQRTLEGSVAAVSTRPQNDKYETIPVPVKINTPTHHAMDFENLKTYIYPTNFEIRDYQYNIVERAFYDNLLVALPTGLGKTFIASTVMLNFLRWFPISKIIFMAPTRPLVAQQIKACCSIAGIPSSKVAILLDKTRRNRAEIWNSRQVFFTTPQVVENDLASGVVNPKSIALLVIDEAHRAKGNYSYNNVVKFINRFSDSYRILALTATPASDVEGVQQIIDNLNISKVEVRTEQSIDIVRHMKRKTVERKTCYPSSEITECIELLAEGITPVLNTAKERGLLDLTDPTRINFLQCMEISRKIVANPTIPEGLKWSNYFILQLLGMVGQCYRRLNIYGIRSFQSYFNEKFLEFKTKWNAKKSTNKLNADFYFSDPITTLMDRVEELSKTLTYGHPKIEALMEELDDFFKNHETAGSRVIIFTEFRESALEIVQCIEKANDNRKPHIFIGQSKEKEKFDVENFGKKKQKGQTKKKKDERPSTRSSSENAQMTGMSQKLQKEIIKKFKKGVFNILVATSIGEEGLDIGEVDLIICYDSTSSPIKNIQRMGRTGRKRDGKVLMLFSSNEESKFDKAMGGYEYIQQHIMKGDFIQLRPQHRMIPDEYKPEAVKQLIQIPEENIELKAEDDEDEIIRIATSYMLGGKGKKGKKANNNSTKKPAKTFFMPDNVETGFKSAATMVRKVGDNKSLAERNKEKTFLDKLVDSDSESEVDKENENVIQEVDKSKNQEQNDHIITELDNTEQSVAGNTKSTTNGTSYSEPENNNQVNQESVTANLDSVARVPEPEVIENSESEEEQISKITHNTPATSVDLSNGPEETSYKIDSVLIDLIDDDFTFSSDTEGDKVEVIDAVSPEVCKLPEKPATPPIRKSLGVKRKVNKTPDPESNSISIPSSTTKKSHNEVTRKVVQDPSTTNKKSLGVKRPRPVSIIDQLKRQKIRSQVIVSRETQSIIEHESRTQSSLPSPRNMSDEISEIDVIIDLDDDDDDDNKVNGHDKSQTTISKVQPIYEFSNKEDEGFLSSSQTRELYKNYYIAIDSSDDIPFYDPVQGFSKIKDTDKFTMGRTGPITHSLRTQRLFQACNAEFDSQLAAQTKDNDKQDYTFILKK
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase MPH1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARCA_BACLD
Sequence: MIMTTPIHVYSEIGPLKTVMLKRPGRELENLTPEYLERLLFDDIPFLPAVQKEHDQFAETLKQQGAEVLYLEKLTAEALDDALVREQFIDELLTESKADINGAYDRLKEFLLTFDADSMVEQVMSGIRKNELEREKKSHLHELMEDHYPFYLDPMPNLYFTRDPAAAIGSGLTINKMKEPARRRESLFMRYIINHHPRFKGHEIPVWLDRDFKFNIEGGDELVLNEETVAIGVSERTTAQAIERLVRNLFQRQSRIRRVLAVEIPKSRAFMHLDTVFTMVDRDQFTIHPAIQGPEGDMRIFVLERGKTADEIHTTEEHNLPEVLKRTLGLSDVNLIFCGGGDEIASAREQWNDGSNTLAIAPGVVVTYDRNYISNECLREQGIKVIEIPSGELSRGRGGPRCMSMPLYREDVK
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCP1_MYCS2
Sequence: MQRVAVMVLAVLLALFSAPPAWAIDPPVIDAGAVPPDETGPDQPTEQRKICATPTVMPNSNFADRPWANDYLRIQEAQKFATGAGVTVAVIDTGVNGSPRVPAEPGGDFVDAAGNGMSDCDAHGTMTAAIIGGRPSPTDGFVGMAPDVRLLSLRQTSVAFQPKGARQDPNDPNTTQTAGSIRSLARSVVHAANLGAQVINISEAACYKVTRRIDETSLGAAINYAVNVKGAVIVVAAGNTGQDCSQNPPPDPSVPSDPRGWREVQTIVSPAWYDPLVLTVGSIGQNGQPSNFSMSGPWVGAAAPGENLTSLGYDGQPVNATPGEDGPVPLNGTSFSAAYVSGLAALVKQRFPDLTPAQIINRITATARHPGGGVDNYVGAGVIDPVAALTWEIPDGPEKAPFRVKEVPPPVYIPPPDRGPITAVVIAGATLAFALGIGALARRALRRKQ
What is the function of this protein?
May play a dual role in regulation of ESX-1 secretion and virulence.  Acts as a protease that cleaves EspB.
What are the official names of this protein?
Mycosin-1, MycP1 protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Cell wall-associated.
Protein: ACT_ASHGO
Sequence: MDSGEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDMTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSAIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLEAAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SEY1_CANAL
Sequence: MELSEGELSHTSSSSSFVPVDQRQLQDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDESNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTSDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLDDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLAKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVIELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLGGYDDSDDEEDHCFAEIITEQEKSEVLAKFKKEVDAKYIETKRSIVQHITQIPYYIYLIILVLGWNEFMAIIRNPLFFSLSIVLGATVYVLYYLGLLRPALVVAQRTMDEVIVMAKTKLREVLIDDHEVTGRQLNKMAGSKENIELDDM
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization (By similarity).  Required for virulence and resistance to cycloheximide.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: RIP2_PHYAM
Sequence: MKMKVLEVVGLAISIWLMLTPPASSNIVFDVENATPETYSNFLTSLREAVKDKKLTCHGMIMATTLTEQPKYVLVDLKFGSGTFTLAIRRGNLYLEGYSDIYNGKCRYRIFKDSESDAQETVCPGDKSKPGTQNNIPYEKSYKGMESKGGARTKLGLGKITLKSRMGKIYGKDATDQKQYQKNEAEFLLIAVQMVTEASRFKYIENKVKAKFDDANGYQPDPKAISLEKNWDSVSKVIAKVGTSGDSTVTLPGDLKDENNKPWTTATMNDLKNDIMALLTHVTCKVKSSMFPEIMSYYYRTSISNLGEFE
What is the function of this protein?
Possesses antiviral potency.  Inhibits viral infection of plants (tobacco mosaic virus) (PubMed:10403789).  Inhibits protein synthesis in both prokaryotes and eukaryotes (PubMed:8034016, PubMed:10403789).
What are the official names of this protein?
Antiviral protein II/III, Antiviral protein II, Antiviral protein III, PAP-II, PAP-III, Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: ATPG_SALPB
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLADMKAWSDKGVQCELAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTITQLLPLPASEDDDLKRKAWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: URED3_METEP
Sequence: MADEAGTRSAGGRPIPAAEPLRPALSRQRSQGAVHLRVAPAGTAADAPTRIVDLAESGPLRLRCPRQGAERMLEGVLVNTGGGIACGDVFTVSVTVEPGGACVLTTTAAEKIYRSDGPCAEIVNRASVGAGGRLDWLPQETILFDRARLVRRFEADLAPDASLLVAEIAVLGRAARGESLEQALFEDRWRIRRDGRLVYADSLRLDGAVTALMNRRAIGGGARALATILDLSLRAEGRLDEARALLDALPAQVEAGASAWNGHLAVRMLAPTVAPLRDAAARFLAAWRGQPMPRVWQT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 3.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SYNFM
Sequence: MSGSPDLVLETDFPGLKLLNRGKVRDIYDLGDSLLIVATDRISAFDVIMPNPVPDKGRILTRITEFWLRFLSDVTENHLISSDVSRYPEQCRPYERVLAGRSMWVKKARVFPVECIVRGYLAGSGWEDYRKTGQVCGIALPAGLQEAQQLPEPIFTPSTKATLGEHDENISFDAMAAAIGEEMAQGVRDVTIKVYLKASSYARQRGIILADTKFEFGLVEGRLTLVDEVLTPDSSRFWPADRYRVGSSPESFDKQYLRDYLVRSGWKKTDPPPVLPPDVVENTRKRYLEALERLSGHGLEG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: IHFB_BUCCC
Sequence: MIKSELFERITEKKTYIPAKIIEYVVKNILEYMSLSLEKGNRIEIRGFGSFSLHYRFARIGRNPKTGEKVYLKEKYVPHFKPGKQLRDRINNIYKKI
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LOXL4_MOUSE
Sequence: MMWPQPPTFSLFLLLLLSQAPSSRPQSSGTKKLRLVGPTDRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKYGQGEGPIWLDNVRCLGTEKTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQHGYHSEKVSNALGPQGRRLEEVRLKPILASAKRHSPVTEGAVEVRYDGHWRQVCDQGWTMNNSRVVCGMLGFPSQTSVNSHYYRKVWNLKMKDPKSRLNSLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPACPGGMHAVVSCVAGPHFRRQKPKPTRKESHAEELKVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYERTLGDCLALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGTVCSDHWGLTEAMVTCRQLGLGFANFALKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQCQRHGPVHCSHGPGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENCLSKSADHMDWPYGYRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDCQWVDITDVGPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDSYRANAELSLEQEQRLRNNLI
What is the function of this protein?
May modulate the formation of a collagenous extracellular matrix.
What are the official names of this protein?
Lysyl oxidase homolog 4, Lysyl oxidase-like protein 4, Lysyl oxidase-related protein C.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MATK_PISST
Sequence: MEEFKGYFEKSGSIQQHFLYPLLFQEYIYALAHNHGLNVNGSIFYELPEISGYDKKFSSLLVKRLITRVYQQNYLINSVNHSNPNRFVGHNKNFYSQMISEGFAVIVEIPFSLRLVSSLEEKKEIPKSQNLRSIHSIFPFFEDNFSHLNWISDILIPYPDHLEMLVQILQCWIQDVPSLHLLRIFFHEYHNWGNPITSRKSNYYGLSKENPRLFWSLYNPYVVKCESIFNFLRKQSSYLRSTFYGTILERTHFYGKMKPFGVTCANDFQKTLWLFKDPFMHYVRYQGKSILVSKGTHLLMKKWKSYFVNFWQCHFRFWSQPGRIHISQFSKFSFYFLGYLSSVPINPSAVKSQMLESSFLIDIVTKKFETIVPIIPIIGSLSKAKFCNVSGNPISKPVWADLSDSDIIDRFGRICRNLSHYYSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLQRLGSEFLEEFFTEEEKVLSLILPRISYPLHKLYRERIWYLDIIRINNLTNHL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BCRB_BACLI
Sequence: MAKKAKYPDVPIRFSETFSDTNLYIVLLIGVPLYGVITSYLFNREYAESTLKNLLTIPVSRISLIVSKLVLLLIWIMMLTLIAWVLTLLFGLIGQFEGLSSAVLIEGFKQFMIGGALLFFLVSPIIFVTLLFKNYVPTIIFTIIISMVSIMVYGTEYSALFPWSAVWVIASGTFFPEYPPEYSFISVAATTVLGLAATIVYFKKIDIH
What is the function of this protein?
Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Bacitracin transport permease protein BCRB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YAJC_CHLMU
Sequence: MFSRVLFSILFFLGCCPSLFADVDSPQRATFGQPAVMLGIAIVFFYFILWRPEQKRRQAMEKRKSELAVGDKVTAMGIVGTIAEIREHTVVLNIASGKIEILKAAISEIFKAEK
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HDAC8_MOUSE
Sequence: MEMPEEPANSGHSLPPVYIYSPEYVSICDSLVKVPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIEYGLGYDCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin.  May play a role in smooth muscle cell contractility.  In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
What are the official names of this protein?
Histone deacetylase 8, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation.