PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_SCVLA
Sequence: MLRFVTKNSQDKSSDLFSICSDRGTFVAHNRVRTDFKFDNLVFNRVYGVSQKFTLVGNPTVCFNEGSSYLEGIAKKYLTLDGGLAIDNVLNELRSTCGIPGNAVASHAYNITSWRWYDNHVALLMNMLRAYHLQVLTEQGQYSAGDIPMYHDGHVKIKLPVTIDDTAGPTQFAWPSDRSTDSYPDWAQFSESFPSIDVPYLDVRPLTVTEVNFVLMMMSKWHRRTNLAIDYEAPQLADKFAYRHALTVQDADEWIEGDRTDDQFRPPSSKVMLSALRKYVNHNRLYNQFYTAAQLLAQIMMKPVPNCAEGYAWLMHDALVNIPKFGSIRGRYPFLLSGDAALIQATALEDWSAIMAKPELVFTYAMQVSVALNTGLYLRRVKKTGFGTTIDDSYEDGAFLQPETFVQAALACCTGQDAPLNGMSDVYVTYPDLLEFDAVTQVPITVIEPAGYNIVDDHLVVVGVPVACSPYMIFPVAAFDTANPYCGNFVIKAANKYLRKGAVYDKLEAWKLAWALRVAGYDTHFKVYGDTHGLTKFYADNGDTWTHIPEFVTDGDVMEVFVTAIERRARHFVELPRLNSPAFFRSVEVSTTIYDTHVQAGAHAVYHASRINLDYVKPVSTGIQVINAGELKNYWGSVRRTQQGLRSGRSYDASCNAYRRTYSWRCPRRVDRTGGQCFSRVNVIEPSHGPRPTRYILQEPGTYPAWIRFRNRVQAVSRQKATHFLFDIVPAAVISDFTTSDTSSFAYKSHTYAVNVTALRFSDTYALYVQTDTNMTILSPAARRQASATYSQVAGFCYNTPTVMDSLANILDVDRNIRPKHFKGLRLYTRSKVTAQHHTHLRPDELVEAAAKVSPRRKYYLMCVVELLANLQVDLEAAVATILAYVLTLSEKFVPIFLDSRAIWVGEPGPDALTARLKASSGQIKSIHTADYEPLTELFELAVLMNRGVGHVSWQAEKDHRLNPDVAVVDQARLYSCVRDMFEGSKQTYKYPFMTWDDYTANRWEWVPGGSVHSQYEEDNDYIYPGQYTRNKFITVNKMPKHKISRMIASPPEVRAWTSTKYEWGKQRAIYGTDLRSTLITNFAMFRCEDVLTHKFPVGDQAEAAKVHKRVNMMLDGASSFCFDYDDFNSQHSIASMYTVLCAFRDTFSRNMSDEQAEAMNWVCESVRHMWVLDPDTKEWYRLQGTLLSGWRLTTFMNTVLNWAYMKLAGVFDLDDVQDSVHNGDDVMISLNRVSTAVRIMDAMHRINARAQPAKCNLFSISEFLRVEHGMSGGDGLGAQYLSRSCATLVHSRIESNEPLSVVRVMEADQARLRDLANRTRVQSAVTAIKEQLDKRVTKIFGVGDDVVRDIHTAHRVCGGISTDTWAPVETKIITDNEAYEIPYEIDDPSFWPGVNDYAYKVWKNFGERLEFNKIKDAVARGSRSTIALKRKARITSKKNEFANKSEWERTMYKAYKGLAVSYYANLSKFMSIPPMANIEFGQARYAMQAALDSSDPLRALQVIL
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome.  Catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded from the virion into the cytoplasm where they function as mRNAs for translation of viral proteins and also as substrates for encapsidation to form new virions.  Once encapsidated, the positive strand is converted to dsRNA by the RNA-directed RNA polymerase.  Displays ssRNA-binding activity.
What are the official names of this protein?
Probable RNA-directed RNA polymerase, Gag-Pol protein.
What is the protein family that this protein belongs to?
Belongs to the totiviridae RNA-directed RNA polymerase family.
Protein: BPIB2_MOUSE
Sequence: MARACSLGLLLLLLLLLRTVVTVSLPVIVVRLNKAALDYVSDIGKAPLQRALQVTISDFMDPSGEVLQSTRVQILDAHVPFFYLKFIAGFGVHLSAAANFTIKVFSVPEPMELVLPVDLLADVHVARDSIGTLVLSVPACSSIFSPAGMLDGSISTSQELLDRVQEHIKADLNNKLCLHVYGLVQDLNVHLGTLIGLSPVGPESQIRYSITSMPTITSNYISLDIGAILSLLGKPILLPMHGAHPFVLPWPLGDAGAMATVGLSQHLFDCALLMLQKAGSLNLEITGQLNSKNNPLNTSVLGQLIPEVAHLFPEPTPLVLKVQLGATPVVTLHTSNSTLQLQPLVEVFAAPSNLALQFLFSLDVMVNLDLQLSVSKAKLRGSTSLLGGFQLSVATSNVGSVDMDQVLTLISTVFQKPLLDHLNALLGMGVVLPRVHNLHYVHSEVLVREGYVVVSSGLAYQH
What are the official names of this protein?
BPI fold-containing family B member 2, Bactericidal/permeability-increasing protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAX_METCA
Sequence: MKLLIDIGNSRVKWARSEPGRYTFGGAFATDASSLAEACESQMAALPRPEAVLVSNVAGMRAGRLLADWASARWVVPVRFVRSEASALGVVNAYPNPAQLGVDRWLGLIGAWRTRRDACCIVSAGTALTIDLLDAEGRHRGGVIGPGLAMMRAALASLEALGGAAESCDGFFCNRTGPALSSGILHSAVGLIRESQARAARLLATEPELLLTGGDAETLRPYLETPVRLVPHLVLEGLHAVAERMP
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_SERP5
Sequence: MQILLANPRGFCAGVDRAISIVERALEIYGAPIYVRHEVVHNRYVVDSLRERGAVFIEEITEVPDGSILIFSAHGVSQAVRAEAKARDLTMLFDATCPLVTKVHMEVARASRRGTEAILIGHAGHPEVEGTMGQYSNPKGGMYLVESPDDVWKLQVKDESNLCFMTQTTLSVDDTSDVIDALRKRFPSIIGPRKDDICYATTNRQEAVRNLAGDADVVLVVGSKNSSNSNRLAELAQRVGKPAYLIDSAADIQEAWLKDAHNIGVTAGASAPDVLVQDVISRLKALGGVNVQEVSGREENIVFEVPKELRVDIKQVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RS2_GEOTN
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKVEEAYNFVRELAGNGGKILFVGTKKQAQESVKEEAERCGMFYVNQRWLGGTLTNFATIQKRIKRLREIEKMEEDGVFDVLPKKEVIGLKKEKERLEKFLGGIKDMKELPDALFVIDPRKERIAVAEARKLNIPIIGIVDTNCDPDEIDYVIPANDDAIRAVKLLTSKIADAVLEAKQGEEAAVAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MURC_ALIF1
Sequence: MTKEQKLQLAEIRTMIPEMRRVECIHFVGIGGAGMSGIAEVLLNEGYHISGSDMAENTVTVRLAQKGAEIFFGHQASNVAKASVVVVSTAIDPSNPEIVAAKENRIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTALTTQIYSEAGLDPTFVNGGLVKNAGTNARLGSSRFLIAEADESDASFLHLQPMVSIVTNIEADHMDTYGGDFETLKQTFIDFLHNLPFYGQAVMCVDDPVVRELLPQVSRQVITYGFSDDADVRLINYRQVGQQSFFTVQRKDRTDLDIVLNIPGKHNALNATAAIAVATEEDVEDEAILTALLNFEGAGRRFDQLGEFETGNGSAMLVDDYGHHPTEVDVTIKAARAGWAEKRLVMIFQPHRYSRTRDLYDDFANVLDNVDVLIMLDVYSAGETPIAGADGRALCRTIRGRGKIDPVFVPTIEALPPVLANIIQEGDLILTQGAGDVGKLAKQLASMELNIETMKKLG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL2_HALNC
Sequence: MDQSARYADLSLKEEDLIAGGKHILVAYKMKPKAGHGYLEASAHFAAESSTGTNVEVSTTDDFTKGVDALVYYIDEATEDMRIAYPMDLFDRNVTDGRMMLVSVLTLIIGNNQGMGDIEHAKIHDIYFPERAIQLFDGPSKDISDMWRILGRPIENGGYIAGTIIKPKLGLRPEPFAAAAYQFWLGGDFIKNDEPQGNQVFCPLKKVLPLVYDSMKRAQDETGQAKLFSMNITADDHYEMMARADFGLETFGPDADKLAFLVDGFVGGPGMITTARRQYPNQYLHYHRAGHGMITSPSAKRGYTAFVLAKISRLQGASGIHVGTMGYGKMEGEGDDRNIAYMIERDEAQGPVYFQKWYGMKPTTPIISGGMNALRLPGFFENLGHGNVINTAGGGSYGHIDSPAAGAISLKQAYECWKAGADPIEFAKEHKEFARAFESFPKDADAIFPGWREKLGVHK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO, Form II RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SETB_ECOLI
Sequence: MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTDEVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWNRNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGPPLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMRKELPLATGTIEAPRRNRRDTLLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFAKRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLMPGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKDV
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the detoxification of non-metabolizable sugar analogs.  Can transport lactose and glucose.
What are the official names of this protein?
Sugar efflux transporter B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Set transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEK15_ARATH
Sequence: MSTDTIPSLSSPPAPEFPSTTPDTATSPAPSQPSIIGPSSLAPFPETTTNIDGGSRNVALTGLITGVVLGATFVLLGVCIFVCFYKRKKRKLKKKKKEDIEASINRDSLDPKDDSNNLQQWSSSEIGQNLFTYEDLSKATSNFSNTNLLGQGGFGYVHRGVLVDGTLVAIKQLKSGSGQGEREFQAEIQTISRVHHRHLVSLLGYCITGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCNPKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHVSTRIMGTFGYLAPEYASSGKLTEKSDVFSIGVVLLELITGRRPVDKSQPFADDDSIVDWAKPLMIQALNDGNFDGLVDPRLENDFDINEMTRMVACAAASVRHSAKRRPKMSQIVRAFEGNISIDDLTEGAAPGQSTIYSLDGSSDYSSTQYKEDLKKFKKMAFESKTFGSSECSGLTSDNGQNPSGSSSITEGQRTTQEIEPEKNTKDT
What are the official names of this protein?
Proline-rich receptor-like protein kinase PERK15, Proline-rich extensin-like receptor kinase 15, AtPERK15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: C2D2A_HUMAN
Sequence: MNPREEKVKIITEEFIENDEDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRRGPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKELETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNFDPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVRPEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYLARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISELLEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTLLAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
Coiled-coil and C2 domain-containing protein 2A.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: YJNA_BACSU
Sequence: MSVSIILMGLFVGALVGLTGVGGAALLTPLLIVLGINPSIAVGTDLVYNSITKLFGVASHWRQKTINFKLVKYLAIGSIPSASLAIGILHLFPAFHQHQEEIIKHALGYVLTLVAISIIVRLFLDRKLRPNRWQLMPLENKRALTILIGVVFGFIVGLTSIGSGSLFAIAMIYLFNMKASQIVGTDIAHAFLLVTAAGILNASFGSVDYMLAANLLLGSIPGVLIGSHLSPRFSPRPLQFIMASIILVSGLKLI
What are the official names of this protein?
Probable membrane transporter protein YjnA.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PID4_CAEEL
Sequence: MNTHNARDSDDESPLESEEHLKRFFAGRNLYSQTKIDDARKKSHDAKYAKEVEWDAKDTAKGKPVFKKYRQEIADKTSRCDAQFINNLHTYYGNGSELRELPETHYAVDFMGTTIATTEMTAELKKLKVLKKKTATSQFVREHRQLGFIPTPSRRSLSCTGRFMNFETKCDERPDRTNPEFSVGNNNFLSATISNLDEDFKTPSNCEHVASIVPKEISNALTALIPHVNVFDYEKGEMEIGKVLCSNKNLHAYVIPKQHDQEQMLKDFSARFLAWYNKLSHLQRDTFGTDKDPKRSGKQEDGKPMKPYFWRVNVILCLQEFQEEGTMFRRARHVCGIRPHKSQPGLDLYIEIDTGSMRALKTNYLTVRKLPQEFANVPTPILEVRFEGAKTEEDVARRIAHIRKTGRAYIKSFDTGKRKIYQNSFFNGQPKDWSNIETAVLLPPKESSMSKLFCEDRDCMGLCCTDQWLENAESSPGISTIPASWIADKNKKPFVDRSPQKFKFPASGSYMKPAN
What is the function of this protein?
Together with pid-5, it is involved in gene silencing mediated by a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and guide the Piwi protein prg-1 to its DNA targets for silencing (PubMed:33231880).  Together with pid-5, it is required for the biogenesis of secondary and tertiary 22G-siRNAs (PubMed:33231880).  Specifically, promotes the production of 22G-siRNAs from the 5' end of target mRNAs (PubMed:33231880).  Together with pid-5, plays a role in small RNA-directed transgenerational epigenetic inheritance (also called RNAe) over several generations and germline immortality (PubMed:33231880).  Together with pid-5, plays a role in the formation of liquid-like condensates in the cytoplasm called Z granules (PubMed:33231880).
What are the official names of this protein?
Protein pid-4, piRNA-induced silencing defective protein 4.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, P-body. Note=Co-localizes with pid-5 at P granules in germ cells.
Protein: SYGB_RICCN
Sequence: MSELLLELFSEEIPAFMQKNAEEGYLNIFTKIFEENEIFAKVQVFVGPRRITLHATHLPKITLPKEEEIKGPSIEAPEAAINGFCKAHNVSKLELPTKLISNQLYYFFVKKTEEREIKEILPEIIIEAINKYSWAKSMFWGDYKIKWIRPLRNILCIFDGEILPMQFGHLTANNITYGHRLTDNKKLEVTDFEDYRNKLLENHVILERAKREAIIKTGLLELASSHELIIKEDNRLVEEVVGLSEFPVVLLGKIPQKFLELPKEVLISSMRTHQKYFCLFDKTGNFTPYFLFVSNGRFTNAELVIQGNEKVLSARLSDALYFCKQDIAKTLESRLGQLEAVTFHAKLGNLREKIERITDICNYIAPNNKDLITAARLCKSDLVSEMVGEFPDLQGIMGYYYAKHEGLNAEIAAAIRDHYKPQGLSDNLPSGNAALLALADKLDSLVGLMIAGETPTGSGDPYALRRQALGIIRIILENKLELNFNDLINFSINLYKDSSDENKNLIISFFEERAKFYFKNDYDIALINAVLDLNLVDTNFKLDALKEFLIEDAGKQLLNAYKRASNIIGDQKITGLVDASLFSTQPEKELFEVIQKISPQIIDSIADKDYKKALNLLSSLLTPITSFFDNVLVNDSDPKIAQNRLSLLQNICELFDKVAKFNRL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUP2_YEAST
Sequence: MSMLRIWSCIVHFFSVQALDSRIKPDIEFKRRQRIFINSSKEENGSSSSAVTVTRNPVLSSNSPSPPLWNTWEFRLYYLAFTVVVPFMIKAALATSSESNPNYYKFSGLLAHGWILGRKVDNSDPQYRFFRSNFFLLAILILLQIILKKVFVKFSKIPKTKFDFACGLVFVCFMYGINSVKLFTHAFIFFTLAHSLKRKRLIAAFAIWSYGIFTLFINQKMKNLPFNNIAIILSPMDQWYKGIVPRWDFFFNFTLLRLLSYSMDFLERWHEQLSRQPSIDYDDRRPEFRKSLSGSTLQTIYESGKNVLEEKERLVAEHHIQDYNFINFIAYITYAPLFLVGPIITFNDYLYQSENKLPSLTKKNIGFYALKVFSSLLLMEIILHYIYVGAIARTKAWNNDTPLQQAMIALFNLNIMYLKLLIPWRLFRLWAMVDGIDAPENMLRCVDNNYSTVGFWRAWHTSFNKWVIRYIYVPFGGSNNKILTSFAVFSFVAIWHDIQLRVLFWGWLTVLLLLGETYITNCFSRYRFRSWYRFVCGIGAAINICMMMIINVYGFCLGAEGTKLLLKGIFNNSHSPEFLTAVMVSLFIAVQVMFEIREEEKRHGINLKC
What is the function of this protein?
Probable membrane-bound O-acyltransferase (By similarity).  Together with GUP1, has an influence on the chemical composition of the yeast extracellular matrix (yECM) in yeast multicellular aggregates, such as biofilms and colonies (PubMed:25589358).
What are the official names of this protein?
Membrane-bound O-acyltransferase GUP2, Glycerol uptake protein 2.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ASIC5_RAT
Sequence: MEHTEKSKGPAEKGLLGKIRRYLSKRPLPSPTDRKKFDHDFAISTSFHGIHNIAQNQNKVRKVIWLSVVLGSVSLLVWQIYSRLVNYFMWPTTTSIEVQYVEKIEFPAVTFCNLNRFQTEAVSRFGIIFFLWDIVSKVLRLQEISGNNTGSPEALDFVASHRNFSITEFVKNNGFYLNHDTLVHCEFFGKTCDPKDFKHVFTEYGNCFTFNYGENVQSKNKVSVSGRGLKLLLDVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTIHQEYPWGECNPDIKLRNFTTYSTYGCLKECKAKHIQRLCGCLPFLLPGNGVECDLLKYYNCVSPILDHIERKGLCTMGTHNSSCPVPCEETEYPATIAYSTFPSQRATKFLAKKLNQSQEYIRENLVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYLFTSFYWVFIFFLLKILEMIQRTSPPQTV
What is the function of this protein?
Cation channel that gives rise to very low constitutive currents in the absence of activation.  The activated channel exhibits selectivity for sodium and lithium, and is inhibited by amiloride.
What are the official names of this protein?
Acid-sensing ion channel 5, ASIC5, Amiloride-sensitive cation channel 5, Brain-liver-intestine amiloride-sensitive Na(+) channel, BLINaC.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO3_THEMA
Sequence: MKKIENLKWKNVSFKSLEIDPDAGVVLVSVEKFSEEIEDLVRLLEKKTRFRVIVNGVQKSNGDLRGKILSLLNGNVPYIKDVVFEGNRLILKVLGDFARDRIASKLRSTKKQLDELLPPGTEIMLEVVEPPEDLLKKEVPQPEKREEPKGEELKIEDENHIFGQKPRKIVFTPSKIFEYNKKTSVKGKIFKIEKIEGKRTVLLIYLTDGEDSLICKVFNDVEKVEGKVSVGDVIVATGDLLLENGEPTLYVKGITKLPEAKRMDKSPVKRVELHAHTKFSDQDAITDVNEYVKRAKEWGFPAIALTDHGNVQAIPYFYDAAKEAGIKPIFGIEAYLVSDVEPVIRNLSDDSTFGDATFVVLDFETTGLDPQVDEIIEIGAVKIQGGQIVDEYHTLIKPSREISRKSSEITGITQEMLENKRSIEEVLPEFLGFLEDSIIVAHNANFDYRFLRLWIKKVMGLDWERPYIDTLALAKSLLKLRSYSLDSVVEKLGLGPFRHHRALDDARVTAQVFLRFVEMMKKIGITKLSEMEKLKDTIDYTALKPFHCTILVQNKKGLKNLYKLVSDSYIKYFYGVPRILKSELIENREGLLVGSACISGELGRAALEGASDSELEEIAKFYDYIEVMPLDVIAEDEEDLDRERLKEVYRKLYRIAKKLNKFVVMTGDVHFLDPEDARGRAALLAPQGNRNFENQPALYLRTTEEMLEKAIEIFEDEEIAREVVIENPNRIADMIEEVQPLEKKLHPPIIENADEIVRNLTMKRAYEIYGDPLPEIVQKRVEKELNAIINHGYAVLYLIAQELVQKSMSDGYVVGSRGSVGSSLVANLLGITEVNPLPPHYRCPECKYFEVVEDDRYGAGYDLPNKNCPRCGAPLRKDGHGIPFETFMGFEGDKVPDIDLNFSGEYQERAHRFVEELFGKDHVYRAGTINTIAERSAVGYVRSYEEKTGKKLRKAEMERLVSMITGVKRTTGQHPGGLMIIPKDKEVYDFTPIQYPANDRNAGVFTTHFAYETIHDDLVKIDALGHDDPTFIKMLKDLTGIDPMTIPMDDPDTLAIFSSVKPLGVDPVELESDVGTYGIPEFGTEFVRGMLVETRPKSFAELVRISGLSHGTDVWLNNARDWINLGYAKLSEVISCRDDIMNFLIHKGMEPSLAFKIMENVRKGKGITEEMESEMRRLKVPEWFIESCKRIKYLFPKAHAVAYVSMAFRIAYFKVHYPLQFYAAYFTIKGDQFDPVLVLRGKEAIKRRLRELKAMPAKDAQKKNEVSVLEVALEMILRGFSFLPPDIFKSDAKKFLIEGNSLRIPFNKLPGLGDSVAESIIRAREEKPFTSVEDLMKRTKVNKNHIELMKSLGVLGDLPETEQFTLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_PSEAE
Sequence: MSQVNMRDMLKAGVHFGHQTRYWNPKMGKFIFGARNKIHIINLEKTLPMFNEALTFVERLAAGKNKILFVGTKRSAGKIVREEAARCGMPYVDHRWLGGMLTNYKTIRQSIKRLRDLETQSQDGTFDKLTKKEALMRSRDLEKLERSLGGIKDMGGLPDALFVIDVDHERIAITEANKLGIPVIGVVDTNSSPEGVDYVIPGNDDAIRAVQLYLNSMAEAVIRGKQGAATSADEFVEEAPAESAEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ORK1_DROME
Sequence: MSPNRWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIPGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQSKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYLRRMLNELYILKVKPVYTDVDIAYTLPRSNSCPDLSMYRVEPAPIPSRKRAFSVCADMVAAQREAGMVHANSDTELSKLDREKTFETAEAYRQTTDLLAKVVNALATVKPPPAEQEDAALYGGYHGFSDSQILASEWSFSTVNEFTSPRRPRARACSDFNLEAPRWQSERPLRSSHNEWTWSGDNQQIQEAFNQRYKGQQRANGAANSTMVHLEPDALEEQLKKQSPGAGRVKKFSMPDGLRRLFPFQKKRPSQDLERKLSVVSVPEGVISQQARSPLDYYSNTVTAASSQSYLRNGRGPPPPFESNGSLASGGGGLTNMGFQMEDGATPPSALGGGAYQRKAAAGKRRRESIYTQNQAPSARRGSMYPPTAHALAQMQMRRGSLATSGSGSAAMAAVAARRGSLFPATASASSLTSAPRRSSIFSVTSEKDMNVLEQTTIADLIRALEVVHTHAVLDEQQQAAAAGGAAGGGGISRGSRKQRKMGNAGLEPPQLPPILSLFAGDQTRTLQAAAANRLYARRSTIVGISPTGGAATAPAARSLLEPPPSYTERAANQSQITAGPSNAPTVQSKFRRRFSVRPTALQIPPGQAPPPGASLMEQSSQTALQRRLSLRPSPLARELSPTSPPGGSGSALPAGAIDESGGTSAQRLLPLPAGTRPSTSSTHSPLSRIVQISQAQRKSSMPSAAATGSSGAPAEK
What is the function of this protein?
Background potassium channel.  Rectification is dependent on external potassium concentration.  Acts as an outwardly rectifying channel but as external potassium levels increase, this is reversed.
What are the official names of this protein?
Open rectifier potassium channel protein 1, Two pore domain potassium channel Ork1.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CWC2_DICDI
Sequence: MTSKKQKSSIDTITPTPPNTTTTTTTTSTTATTKDKKKSKKPKSSGLTKVGADIIELQASLLNRPARKQATHVNSRYEDHDTDTTEYNIWYHKKLGNRNWKDRDVSETRCNVLKDCGKTRANKDANFCCYFARGKCINGADCTSLHRIPTPEDDKRLRLTHDIFGRERHKTDRDDMNGVGSFSRDNRTLYIGGIKTNVSGSLEDMVRKNFEEWGRIEYVRVITNRSISFVRYLTRSSAEFAKEAMTDQTLDNGELLNIRWATEDSNPYAKKVDERNLHRVATEVINKRIREMTPDDQSALKYQMTGQYPNTDQQYDQNGQPINASPSTPYQLQYRGSTKYEAHPYARQYNNDLQKRVQSGETVDVAPLNGVGNYYSHSVGTMNQELQKQQYDNYMQQYYQAYGYDYSKLSDDQKLQLQQYFQSYYYGNQQEQQQQETQQIQNNNENNNDNEEEDDDDEDDDDDNEDDDNDNEETKDNKNDKVENKEEENKEVQEKINTESKEDTKNEEQEKKEEKEKTDSDNIVNKED
What is the function of this protein?
Involved in pre-mRNA splicing.  Binds RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor cwc2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METAS_ECO55
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLGPEVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_KOCRD
Sequence: MENPRRVQILRAIVEDYVHSREPVGSKALVERHRLPVSSATVRNDMAALEEAGLIVAPHTSSGRIPTDRGYRVFVDQIAALQPLTGAQRRAIQVFLEGAHDLDDVMERTVRLLAQLTHQAAVIQYPVRAGITVRHVELVDVGAGTVLVILIPTSGRVAQRAVELAEPLDEVQLLELRARVLARVLGSTLETVPGRVAGLAEELPEALRHAGDRVSEALAVLAAASDEHRLVMAGTANLARFSGDFPQSISPVLEALEEQVTMLRLLSAMQQDERGVAVRIGSEECDDPLAEASVVATGYGPHAASKVGVVGPTRMDYPTTMAAVRAVARYLSRNLGD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RRAA_SHESH
Sequence: MEYNTSELCDTYIDVVDVVEPMFSNYGGCNSFGGSISTIKCFEDNGLIAEALQQDGEGKVLLVDGGGSLRRALLDASIAQLAVDNKWEGIIIYGSVRDVDALEDLDIGIQALASIPVGADENSVGELEIPVNFGGVTFLPLDHVYADNTGIILSPEPLDME
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.