PharMolix/UniProtQA huggingface dataset:
Protein: RPIA_ACIBC
Sequence: MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIDLLPELQLEAAVASSQATADRLKKLGIEVVDMNHVGSLDAYVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVDQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYREGVVTDNGNVILDVFNLNILNAIDLEKTINNIPGVVTNGIFALNPATIAIVATNDGIEERTAQ
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MYO3A_HUMAN
Sequence: MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPKTLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRERRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS
What is the function of this protein?
Probable actin-based motor with a protein kinase activity.  Probably plays a role in vision and hearing (PubMed:12032315).  Required for normal cochlear hair bundle development and hearing.  Plays an important role in the early steps of cochlear hair bundle morphogenesis.  Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern.  Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments (By similarity).
What are the official names of this protein?
Myosin-IIIa.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Note=Increased localization at the filodium tip seen in the presence of MORN4.
Protein: KITH_LISIN
Sequence: MAQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREATPIFSDTNIFEIVANIKPKPNCVLLDESQFLEKEHVFQLAKIVDDLNIPVIAYGLKNDFRNELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKGKPVYTGEQIMIGGNDHYYPVCRKCHANPPIK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y536_MOOTA
Sequence: MTGGQGVTIKELPAELRPRERLLAAGVQALSNAELLAILLRTGTRTESALDVARRLLSGPDGLQFLAGATLEELQQQKGIGLAKAAELKAALELGRRLAAFTLSRTVIRNPRDVAGLLLDEMRYLDRENFRTVSLNTKNQVLGIDNVSVGSLNSSLAHPREVFKDPIRRSAAAIILAHNHPSGDPTPSQEDIMVTRRLVEAGHILGIEVLDHLIIGDGRFTSLKERNLL
What are the official names of this protein?
UPF0758 protein Moth_0536.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: GRPE_STUS1
Sequence: MADEQNLDNQNPETPEQSQADVAEDLAARVQSLEEQLAAAQDQSLRVAAELQNIRRRAEQDVEKAHKFALEKFAGDLLAVADSLERGLELSNPDDEAVKPMREGVELTLKLLLDTLARHQLEQLDPHGEPFNPEHHQAMAMEESTHVEPGSVLKVFQKGYLLNGRLLRPAMVVVSKAPADAPPSIDEKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
Protein: PRS48_HUMAN
Sequence: MGPAGCAFTLLLLLGISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQDTTADVALLKLSSQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGKSLPGVYTNVIYYQKWINATISRANNLDFSDFLFPIVLLSLALLRPSCAFGPNTIHRVGTVAEAVACIQGWEENAWRFSPRGR
What are the official names of this protein?
Serine protease 48, Epidermis-specific serine protease-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_COXBU
Sequence: MKPSLIEKLKTLTYRYSEIGGLLSDSTVINDQDRYRELGKEYAQLEPIVKCFQQFQQNEKAIESAEEMQQEKDPELRKLAEEELEQLTLKKEELEDQLKLLLVPKDPNDERNVFLEIRAGTGGNEAAIFAGDLFRMYARYAETKGWRVNIVSAHEGEHGGFKEVIARVIGEGVYSQLKFESGAHRVQRVPVTESQGRIHTSACTVAIMPEVDEIDQIKINPAELRIDTFRASGAGGQHVNRTDSAIRITHLPTGVVVECQDERSQHKNKARAMSLLQSKLLAAERAKQDQEQAAKRKSLVGSGDRSERIRTYNFPQGRVTDHRINLTLYQLDEVIEGDLDPVIGPLIRELQAEQLAELSGE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_RHILW
Sequence: MVFFPHRHLIGIKGLTEQDITYLLDKADEAVKISRQREKKTSTLRGLTQINLFFEASTRTQASFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMRPDVLVIRHSSAGAAALLAQKVSCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLNAMGARVRVVAPATLLPAGIADMGVEVFHSMKEGLKDADVVMMLRLQRERMSGAFVPSVREYYHFYGLDAETLKAAKEDALVMHPGPMNRGVEIASEVADGPQSVIAEQVEMGVAVRMAVMETLLVSQNQGPRTDGLKA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: HIS7_MYCUA
Sequence: MTATETGTAVRRARIERRTRESDIVIDLDLDGTGQVDVDTGVPFFDHMLTALGSHASFDLTVRTKGDVEIEAHHTVEDTAIALGQALGQALGDKKGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHTGEPDHLQHTTIAGNSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_SALNS
Sequence: MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWDVNAVAARVLPVLEEIQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDDANELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLQ
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: V2_SPTNK
Sequence: MRGVKIPELSKIMRELKTKELKKLLRYELDESTSVDSDEEQDDPGVPFYYEELEKCKTMKELYKFAREYDLQIPRIDKNDIFLKACKELNKNNIFDPNEDIIFEGVIIDPVVIG
What are the official names of this protein?
Uncharacterized protein V2.
Protein: RS14_XYLFT
Sequence: MAKISMINRDLKRKRLAKKFADKRLSLKKVISSYASSYEEKIEASCKLQKLPRDSSPTRLRNRCEISGRPRGVYCKFGLGRNKLREAAMRGDIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TAU_GORGO
Sequence: MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMLQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGEQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAKGAIHLPVDFLSKVSTEIPASEPDGPSAGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPESSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKYVSSVTPRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
What is the function of this protein?
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity.  The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.  Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.  The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization (By similarity).
What are the official names of this protein?
Microtubule-associated protein tau.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Protein: YIW0_YEAST
Sequence: MEMTLFLNESYIFHRLRMWSIVLWHSCVFVCAECGNANYRVPRCLIKPFSVPVTFPFSVKKNIRILDLDPRTEAYCLSPYSVCSKRLPCKKYFYLLNSYNIKRVLGVVYC
What are the official names of this protein?
Putative UPF0377 protein YIR040C.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: CP1A2_CHICK
Sequence: KFLQIAVEEHYQSFDKNNIRDVTDSLWRSKKTKPRGAADPNEKIINLVNDIFGAGFDTVTTALSWSLMYLVTQPHSQKKIQESELDTAIGRERRSWLSERSMLPYKEAFILETVPTWQFVPFTIPHSTTRDTTLNGFHIPKECCVFVNQWQVNHEAELWEDPFVFRTERFLTDDSTAIDKTLSEKVMGKQVGLAWKSALGTRQWEVSFYLSTLTPNWSSAPGGESKKDRVRPIYGLSMKHKRCEHFQVKKRFSMKSSN
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A2, CYPIA2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: CH60_COXBR
Sequence: MAAKVLKFSHEVLHAMSRGVEVLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQMVKEVASRTSDDAGDGTTTATVLAQAILVEGIKAVIAGMNPMDLKRGIDKAVTAAVAELKKISKPCKDQKAIAQVGTISANSDKSIGDIIAEAMEKVGKEGVITVEDGSGLENALEVVEGMQFDRGYLSPYFINNQQNMSAELENPFILLVDKKISNIRELIPLLENIAKSGRPLLVIAEDIEGEALATLVVNNIRGVVKVAAVKAPGFGDRRKAMLQDIAVLTGGKVISEEVGLSLEAASLDDLGSAKRVVVTKDDTTIIDGSGDAGDIKNRVEQIRKEIENSSSDYDKEKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALIRVLKSLDSVEVENEDQRVGVEIARRAMAYPLSQIVKNTGVQAAVVADKVLNHKDVNYGYNAATGEYGDMIEMGILDPTKVTRTALQNAASIAGLMITTECMVTEAPKKKEESMPGGGDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBPH_CAEEL
Sequence: MGNTLTGRSNAIAPIISAEDAKTYISDEEYRRIRQAFQRFKNGCINYDEFCYHVLGGAQIPEEKRRLLFSFFSHGAETISFDNLLSSLVGLCRVEEVQSRFIEEYHEFASWGLSPPKLTIPLNDSYISFYEVMSYVTHLSVNEVIELEKVFATISDRAVCKLNEEKWKQALGGCFPDSYAERLFAVFDENRDGQIDFRELVCTLSALCRGPLPGRISQLARIWDVDCDKLLSDEELSNMYKDLNVPEEHQTVTKSSNGKSALVDFGIWAQENEKYVNEYYSMALQIGHICLGLRPESRKMELQIVNEFEKRASELPLSEWNIVASGWHAELRSFLEADKNPNPIDNSGIKGTREDSWTSKVACISAESARLKPDLIPSDYIRVPVPLWRAWLRWHGCALTVDSQFTRKYLDGEFFEDNKPALELYPLEILLLGHDRKKSQDGTENTPRSLTSWACAQVSRSMTVDELLALCKTELRLGDGDARLWQVVKENEEGNVLLDDGAQNLHQLYSSLGKTKKVNKMKLLLEVRERGTGVWPEELRASLSGKQITAASTLSSNAQLSDSSGRPGAVGLVNYGNFCYRNAGIQCLARVSPLTQYFLDEDNLDAIKRGNLRRGDAAETTIEYAKLLREMWAAKKKNIAPNDFNDAIRLSSDMFECSEQHDCQEFVAFLLDQLHTSMYESNKSLHPSPEESEGTDSNKLSDSSKKKEADKEEADEEKAERSWTEYEKQNESLVTQLFTGQLRSRLICRTCQSSSSVFEPFTSLSLPIGFEDVDLYQVIVVHRDGRIPRRYGFRLSRDSKVGNLREVVAVSSGISMSHLTIQCMSSKGTLMSRSPNHRSSNLRDELPLSSFPSGARLYALELPESTGEDQWRVAMHRKLQYNHEPYILGSTAGFIVSRFGLPLIVGLDEEVTGKKLYEDVMYQMHRFMEHSVNSSSSRAHDPCEDENSGYPFTLCLVDPNYEWCGQCPALRFCRGCPIRPDESKVFIPANCPIAVDWLPIALYLRYNHSQEQACEDDPSVAETWSRHFAPSSLEHCIEKFSCPETLDAAIQCDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFLREQGRMGKCKRTVNFPLKHFDPAPFVDKPDGNTYECIALANHYGQLSCGHFIAYAKSNEDKWLLLNDCSVREVSEEEVDKQGAYLLFYERKDVK
What is the function of this protein?
Ubiquitin-protein hydrolase which cleaves ubiquitin from ubiquitinated proteins (PubMed:12006614, PubMed:11683918).  Plays a role in embryo osmoregulation (PubMed:12006614).  Probably by regulating osmosis, controls actin redistribution in the 1-cell embryos and thus actin-dependent processes such as cytokinesis and P-granules segregation (PubMed:12006614, PubMed:11683918).  During the first embryonic mitotic division, involved in the formation of a functional microtubule organizing center provided by the male pronucleus (PubMed:11683918).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase cyk-3, CeUBP130, Cytokinesis defective protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center. Note=At the 2-cell stage embryo, localizes to the microtubule organizing center during mitotic metaphase. Localizes to the cytoplasm in germ cells and sperm, and to the nucleus in oocytes.
Protein: AROD_LACLM
Sequence: MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKILFTLRTVREGGNIQVSEKKYLQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSYHNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDLLQITRDMTLEYGNHFISMAMGDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: RECF_MYXXD
Sequence: MRLLALHVHDFRNLPQVQLTPSAHATIAVGQNGQGKTNLLEALYFLATLKPLRAGRLSELVRWGSQGARVTGRFLLKGAEREIAVEVGGGTRQAFVDGKKASSLEDYFGGVSVVAFTPDDLEVVKGGPDSRRGFLDRAVFNRFPAFLRESREYARALKNRNRLLREGHTVDAVYLEAYDETLAKAGARIYSRRRALMAELAPRAQATFASIGRTVDPAVYNYRPAHLEGDFAAADETALAAMLRESLSARLRRDMERGFTSVGPHSDDVSVTLGGRSARAYASQGQQRALVLGWKIAEIENLEAAMGFLPLLLLDDVSSELDPERNAYLMGYLAQSGAQVVLTTTDGSLVRGAAADDTLWLDVHGGQVAVRADAEPPPAN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_SALPK
Sequence: MSAIAPGMILFAYLCGSISSAILVCRIAGLPDPRESGSGNPGATNVLRIGGKGAAVAVLIFDILKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKLKKKRQKD
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXJ_VIBVY
Sequence: MSSIYLGVNIDHVATLRNARGTKYPDPVHAAEVAERAGADGITIHLREDRRHITDRDVRILRETLQTRMNLEMAVTDEMIEIALKTQPEYVCLVPEKREELTTEGGLDVAGHLDKIKAATEKLTAAGIKVSLFIDADREQIDAAKACGAPFIELHTGHYADAATEADQLDELKKIAAGASYAADLGITVNAGHGLTYHNVAPIAALPEIYELNIGHAIIGRAVFDGLHKAVADMKAIMVAARQ
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDC_ENTBH
Sequence: MTENSELNNKISTIKLKKLIEIQNLTDNMNGTVIRIRGFIESITSCSSQIFILLRDRLEKVQCIIFKSTNVSSIYEFSRLKKLPLESFIEIEGQVVFAEIPIKRATKQNIEIVISTLNILGPVVSKLPFQLKDCKIAGKESDTNTITVGYNLRLDNRFLDFRLPVTQSIIKIIDQTMYTFRTYLRTHEFIEIKTSKIIQSGSEGGANLFSLNYFNKPAYLAQSPQLYKQLAIIGGLKRVYEIGHVYRAEVSNINRYLSEFVGLDIEMEMETTYIDFIHFLHSLFINIFESFKNEMKKELEIIRQYYEFVDLKYRSTPIIITYKDAVDMLKSKNIQIDYGCDFSREHERILGKIIKDKEDIDIFTIIDYPSSIRAFYSYIDETTKLTRSYDFIVRGEEILSGAQRENRYDYLKNAVIDKGLNPENLKNYLEAFKYGAPPHIGCGIGLERFLKAYFGFDDIRYFSLFPRDPNRIFP
What are the official names of this protein?
Probable aspartate--tRNA ligase, cytoplasmic, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHPC_ECO8A
Sequence: MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
What is the function of this protein?
Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
What are the official names of this protein?
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MhpC family.
Protein: RL16_SALTI
Sequence: MLQPKRTKFRKMHKGRNRGLAAGADVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: P10_ASFK5
Sequence: MPTKAGTKSTANKKTTKGPSKSGSAKGHTGKTHATALHHGMLYKDMVNIAKSKGIPIYQNGSRLTKSELEKKIKRSK
What is the function of this protein?
May play a role in genome packaging through direct interaction with viral DNA.  Binds to ssDNA and dsDNA with the same apparent affinity in vitro (By similarity).
What are the official names of this protein?
Structural DNA-binding protein p10, p10.
What is the protein family that this protein belongs to?
Belongs to the asfivirus P10 family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with the viral nucleoid.
Protein: USP_VICFA
Sequence: MEFAHLTVLSLFCLAFVGITATSSGEDYWQSIWPNTPLPKTFSDLLIPSGITNSLPIKSEELKQYSTLFFEHDLHPGKNFNLGHTNSVGSIIRPFTKSRQGVTDSIWLANKEKQSLEDFCYSPTAIAEHKHCVSSLKSMIDQVISHFGSTKIKAISSNFAPYQDQYVVEDVKKVGDNAVMCHRLNFEKVVFNCHQVRDTTAYVVSLVASDGTKTKALTVCHHDTRGMNPELLYEALEVTPGTVPVCHFIGNKAAAWVPNHTADNLCVM
What is the function of this protein?
Associated with the protein storage vacuole formation.
What are the official names of this protein?
Unknown seed protein USP, VfUSP.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack. Prevacuolar compartment.
Protein: RUTC_METEA
Sequence: MPKTVVIPPGTGKPLAPYVPGTLADGVLYVSGTLPLDAEANVVHEGDAGAQTRHVLETIKGVVEAAGGSMDDITFNHIFLKDWADYGAINAVYATYFPGEKPARYCIQCGLVKPAALVEIASVAHIGKPV
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.