PharMolix/UniProtQA huggingface dataset:
Protein: SCT1B_MOUSE
Sequence: MLAYSVTSSGLFPRMLWALLLLAASLNAHNDVWDEPCCTEHEVSVNRGSRVVMACNISNNLRDVTIELVTSEKTSIIFNHTPPGNYSKDSWQLHIQGVQAQLVITDAQDKHSGNYSWKLHGFQAEFKNFNLTVNAADRQKTEDLPVTKVPDKPPTAVRTEVIIIIAIATTIIITGIGVFVWYKQFPVAPQIQMSVPCLIHGSPGIPYLTLPP
What is the function of this protein?
May be involved in thymocyte signaling.
What are the official names of this protein?
Secreted and transmembrane protein 1b, Protein K-12.
What is the protein family that this protein belongs to?
Belongs to the SECTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: VM1AD_CROAT
Sequence: MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKELFSKDYSETHYSPDGRKITTNPSVEDHCYYRGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKLENVEKEDEAPKMCGVTQNWESYEPIKKASDLNLNPDQQNLPQRYIELVVVADHRVFMKYNSDLNTIRTRVHEIVNFINGFYRSLNIHVSLTDLEIWSNEDQINIQSASSDTLNAFAEWRETDLLNRKSHDNAQLLTAIELDEETLGLAPLGTMCDPKLSIGIVQDHSPINLLMGVTMAHELGHNLGMEHDGKDCLRGASLCIMRPGLTKGRSYEFSDDSMHYYERFLKQYKPQCILNKPLRIDPVSTPVSGNELLEAGEE
What is the function of this protein?
Snake venom zinc metalloproteinase that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins).
What are the official names of this protein?
Snake venom metalloproteinase atrolysin-D, SVMP, Hemorrhagic metalloproteinase atrolysin D, Hemorrhagic toxin D, HT-D.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COX3_TETNG
Sequence: MAHQAHAYHMVDPSPWPLTGAVAALLLTSGLAIWFPFNSLILLTLGLVLLLLTMYQWWRDIVREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGIVPLNPFEVPLLNTAVLLASGVTVTWAHHSIMEGERKQAIHSLTLTILLGFYFTFLQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAICLLRQIRYHFTSEHHFGFEAAAWYWHFVDVVWLFLYISIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: E3GL_ADE05
Sequence: MIRYIILGLLTLASAHGTTQKVDFKEPACNVTFAAEANECTTLIKCTTEHEKLLIRHKNKIGKYAVYAIWQPGDTTEYNVTVFQGKSHKTFMYTFPFYEMCDITMYMSKQYKLWPPQNCVENTGTFCCTAMLITVLALVCTLLYIKYKSRRSFIEEKKMP
What is the function of this protein?
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface.  Also delays the expression of class I alleles that it cannot affect by direct retention.  Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
What are the official names of this protein?
Early E3 18.5 kDa glycoprotein, E3-19K, E3gp 19 kDa, E19, GP19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E19 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: SCARL_ARATH
Sequence: MPLVRFKIRNELSLGGPEIQRSASVEDEEPKAILGAVEVAGLIGILRQLGDLAEFSAEVFNGLQEEVTVTASRCQKLTSRVRRIESALSPLEKAVLSQTSHIHFAYTAGSEWHPRIRNGHSHFVQSDLPLCVMESYEQCRDPPPLHLLDRFAVGGPGSCLRKYSDPTFFRKELSNPSKTDDIKVQRDQAHRKRKKKRLPQRNICRSNAVSTSDETNGAHLSSFTDDRPTTSRSTSTVDMPRSSNMQDLSDIVDQSYLQGQSGAQEQSEAQVQSDFQESSKARDSITGSGYIEYVINQSPVDKPEVKLVEGFLSGSLCPADRIGSTVPEGCIEVVDDNILYSPSEDLLVPSASNVCDEKKETLESMVEKSRKDDEPSELHESKFGPVTPDRVRQNQRDFDRTYILFDEVDIVGEKQSKSQANNIDGTLGIENEGEDKSEQESEADEFVDARNTIESESESDIDGVPKPKLEHYFGDISTYCSEDANSDNNDGSEDITYEEMAHDPRHENSEDESCSGSYLPEDSNVSSCLSDPVCEETLFHDENSQKPWEFFTMCPSLLAEKAVPDVTILREEPVMAHPLFAGDSANEKISSEERIISCPSLKDAIPAEKILPEEHLVNYPSLEAIPHEKILPGESIAKYPSFAEIIPQEKILSEKSLEEAVLDNMTPAGEPDAAHPSFPKAVQDKKISPEVLDSKIFSVPKAVSQEPISLEEFVRIHPCLAEAVPDERFLIEEPPSTCLSLTKAMPTEILLPEKTLESSHYLEELPEEDILQEKSVDSTHPSCAKAAAETNLSPEVLDSTKLSVAEAVPQEQVSLEEFVGINPCLVEAVPDERLLPEEPDTTYLSLTKAVAIEKVLSEELLETYPSLAELPEEEFLQEETDDATHTSEAVSDEEISQEVSDSTNLSLEEALPLEHISHEEFVGIDQCLVEVAPEERFLPEEPVITCLSLTMEGVLSEKSPETYPSLSELPEEKILDEEADDAMHPCLSEAVSDEQSSPNVLGSTNSPVAEAVPQAQISVEEFVGIDPCLVEAVPDMRDLPEEHITSCIYLTNVVPIEEVLPEEPFEACASLGKLPKDKISQEESDEATHTLSCAKAESDEHVSLEVLNSTNLSAAEAIPNEQVTLDEFVGIDPCLGEVVLDEEVLPEQLDTTCRSLTKAAPIMTIFPEEPPEVYPSLEELPEEKIAQEEEVDDATHPYFSEAVCDEKIPPLEDPGSTHPSLEESVPYEEASHEELVGTNPFLESAFPNEIGFPDEPGVTYRSSAEAVSKEKNLPEESLPTYPSWAEVVPDEKISREELDSTYPSSAEAVFDENISGSEAPGSTTETGRQNKTFPEKTFATENSLNEAVFDEKIPGSEASTSTTETGPHNKTFPEEPFAMENFLNEAVFDEKIPGSEAPVSTTETGLHNETFTEEPVATDISLNEAVFGEIIPGSEAPGSATETGLHNKTFPEKPFATDLSLKEAVFDEKIPGSEASSSTTETSPHNKTFPRETITTDLSSTEAVFDEKITGSGVPSFTTETGSHNKCFPEEPVPKENILPKEPAAAYLALAEGIPDQKVFLDDAALLLFAEAIFDQKFSPEVPDSTYPSLKEPEMHVAAPCVVTDLPAKNIKVKEGEVHNEPYTASDVSMNQKSGLLEPESTERTFPSSGGTVTISPDTQNSLPNGTSVESISIWSNGGLLGLAPLKPPVFAEPNSGSQHIKHEINEASVLSTRKQESSSRSVENAEKSSLPLIVSDPTSQQQSNMSSLSPMQSTGTSFRVFGLSHRLLMAGFRGNSSSTCKFESVPSSSYDTRVAAIEDRTQQSPGGSSFEEQLDYESSLFGSPTSSPPVEHMKISFNPIEASPVPKLKLRIPCQPRYNGENADMFPSFQLVPEASNSDDGDDNSDTFCQSSPCVSDYCLSDSELWESDESPRISVSSLKQVEERSRHGDMGSFSGSFLDLPCYDAVDHQSTFSRLEQEQVPEYKPSVSEIIRAWPPNQPKSSPCNEANVDANTVSKKTQDQSLGLVATDDEGGDSVCLDEHKTKGI
What are the official names of this protein?
Scar-like domain-containing protein WAVE 5.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
Protein: LPXB_GLOC7
Sequence: MRIFISTGEVSGDLQGAMLIEALKRQAALKAMDLEIVALGGDRMAETGVSLLGKTPKIASIGLIEALPFIMPTWKLQRKAKQYLQENPPDLLILIDYCGPNVAIGKYARKNIPQVPILYYIAPQAWVWTTNKKTTQDLVNITDHLLAIFSEEARYFAQKGMSVSWVGHPILDRMAQAPTREEARQKLGIKPDQTAIALLPVSRKQELKYLLPVVCQAAQQIQEKLPDVQFLIPLALEDYRSTISAMMEEYGLQGTILDGKSLDALAAADLAIAKSGTVNLELALLNVPQVVVYRLTPLTLWIAQNILKFSVPFLSPVNLVVMEEVVPELFQERATPEQIVQESLDLLLNPQRRQKTLSDYQRVREELGEVGVCDRAAQEILDYV
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RL44_COPCI
Sequence: MVNIPKTRRTYCKGKTCKKHTPHKVTQYKKGKDSIFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQVSLKRCKHFELGGEKKTKGAALTF
What are the official names of this protein?
60S ribosomal protein L44, 60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: MTNK_CITK8
Sequence: MSQYRTFTAQDAVEYARTFGGIDDPSTLVEAQEVGDGNLNLVFKIFDTTGVSRIVVKQALPYVRCVGESWPLTLDRARLEAQTLVAHYQHCPQHTVKIHHFDPELAVMVMEDLSDHNIWRGELIKGAWYPQAARQLGEYLAQTLFHTSDFYLHPHDKKAQVATFINPEMCEITEDLFFNDPYQIHERNSYPAEIEGDVAALRSDAQLKLAVAALKHRFFSHAEALLHGDIHSGSIFVADGRLKAIDAEFGYFGPIGFDVGTAIGNLLLNFCGLPGHLGIRDAAAAREQRLTDIQELWNTFAERFQVLATEKTRDAALRAPGYASEFLKKVWADAIGFCGTELIRRSVGLSHVADIDTIQDAEMRHECLRHAITLGKALIVIADRIESVEALIARVRQYS
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: DICT_DICLA
Sequence: MKCATLFLVLSMVVLMAEPGDAFFHHIFRGIVHVGKSIHKLVTGGKAQQDQQDQQYQQDQQDQQAEQYQRFNRERAAFD
What are the official names of this protein?
Dicentracin, Dicentracine.
What is the protein family that this protein belongs to?
Belongs to the pleurocidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2250_MYCTO
Sequence: MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT2310.
Protein: DFA26_MOUSE
Sequence: MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL
What is the function of this protein?
May have microbicidal activities.
What are the official names of this protein?
Alpha-defensin 26, Defensin-related cryptdin-26.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDC5L_MOUSE
Sequence: MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNNSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQQRYADLLMEKETLQAKF
What is the function of this protein?
DNA-binding protein involved in cell cycle control.  May act as a transcription activator.  Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Cell division cycle 5-like protein, Cdc5-like protein.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=May shuttle between cytoplasm and nucleus.
Protein: TRMB_ECO24
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL2_STAMF
Sequence: MGKRILPQRMGRGTPTFRSPSHRRVGPAKYPPLKLDRTIKGKIIDLLHDPGRWVPLAKIVLEDGTTFLTPAVEGMYVGQIIEIGPDAHISNGNILPIGKIPEGTQIANIEKRPGDGGKFVRSSGTYALIVGRAGTKTQVQLPSGKIIEVPNNARATIGVIAGGGRDEKPLLKAGNAYHKWKVKAKKWPKVRGVAMNAVSHPHGGGSHQHVGKPSTVARETPPGRKVGHIAARRTGRRKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: YL678_MIMIV
Sequence: MWKDNRISEVFIKKKGIGMIALADIPANTLIMKELPISIVKINNQTVSDIFQILYDVLSDPNKKSLFEKFLPNSINEFESHRNNLMKEFHKLKKSRLNNVYQFINNNFTSDEILLYGAKYMCNAFEFNNGSAILINGAKFNHSCVPNVIFVSDENYMYFYTVRNIKTGEELTDNYVDIMSNTKTRKNRLFNQYGFDCQCERCIGSDKLFYQEVEKIQSSKFYFSNQISVNHRKKLQQNSKNLKKNPKKTIKATPK
What are the official names of this protein?
Putative SET domain-containing protein L678.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: O16A_CONCN
Sequence: MKLTCMMIVAVLFLTAWTFVTADDSRNGLENLSPKARHEMKNPEASKSNKRYECYSTGTFCGINGGLCCSNLCLFFVCLTFS
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin-like CnVIA, Delta-CnVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRH_CUPPJ
Sequence: MPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAEIVKLGVQVAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHANIEGRVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGVYTADPKKDPSATRYTTITFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKPGALKRVVLGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_BORPD
Sequence: MATSPQTDPQHDDRPLPQDFETALAELETLVAAMEDGSLPLEQSLAAYRRGVELTRVCQERLAQAEQQVKVLEDGLLRPLDPRALDDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_FRACC
Sequence: MYEGIVQDLIDELGRLPGIGPKSAQRIAFHLLAADPVDVRRLATALTEVKEKVQFCRSCFNVAQSELCRICSDPRRDPSSICVVEEPKDVVAIERTREFRGRYHVLGGAINPIGGVGPDDLHIRELVARLADGTVTELILATDPNTEGEVTASYLARQIAPMGLKVTRLASGLPMGGDLEWADEVTLGRAFEGRRVVSA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SOMA_MELGA
Sequence: MAPGSWFSPLLIAVVTLGLPQGAAATFPTMPLSNLFTNAVLRAQHLHLLAAETYKEFERTYIPEDQRYTNKNSQAAFCYSETIPAPTGKDDAQQKSDMELLRFSLVLIQSWLTPMQYLSKVFTNNLVFGTSDRVFEKLKDLEEGIQALMRELEDRSPRGPQLLRPTYDRFDIHLRSEDALLKNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCNI
What is the function of this protein?
Growth hormone plays an important role in growth control.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYGB_HUMAN
Sequence: MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD
What is the function of this protein?
Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852).  Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).  However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).
What are the official names of this protein?
Glycogen phosphorylase, brain form.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: YD2D_SCHPO
Sequence: MNATQKKKNEKKTKNPYSHNHVNTKLILPHNTFLTNILFLLGLIKHTNQLTFPSIPHSSAISTLLKQTPLPTRILFLSLCLTPSSASARSSDGIILFPHPS
What are the official names of this protein?
Uncharacterized protein C56F8.13.
Protein: Y1091_ACIF5
Sequence: MPSFDVVSEVDMQEVDNALHTTVKEITTRYDFKGSKASMERKEKEIILVAEDEYKLGQMIDLLSARLVKRGVDLKALEVGKVAAAAGGMERQVLSLKVGLETEVSKRMIKFLKDGKFKAQGSIQGDQLRVSGKSRDELQAAIAALRGHDFGLPVQFTNFRD
What are the official names of this protein?
UPF0234 protein Lferr_1091.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TPS2_RICCO
Sequence: MSAQTLAISNLKPNTTRHLASFHPNIWGDRFLSCAAESTDIEDDMEQQVERLKEEVKKMIASADEPSQILNLIDLLQRLGVSYHFEKEIEEALQQVLNMNSDSDKDDDLHSVALRFRLLREQGLNVSCDVFNKFRDRNGHFIQTLKTDLQGMLSLYEAAHFRVHGEGILDDALAFTTTYLESIVPNLSPPLAAQISRTLRQPLRKSLARVEARHFISIYQEDTSHNEVLLTFAKLDFNLLQKLHQKELKYISLWWKDLDFVNKLPFTRDRVVEGYFWILGVYFEPQYHRARKFVTKVINVVSVIDDIYDAYGTLEELVVFTDAINRWDIDCIDQLPEYMKVCYKALLNVYEEIERALSEQGRSYRLHYAKEAMKKLVQAYLVEANWMNKNYVPTMDEYMSIALVSCAYPLLTVTSFVGMGDIATKEVFDWASNDPKIVRVASIICRLMDDIVSHEFEQKRGHIASSVECYMKQNGVSEEATRDEFNKQIVDAWKDINEEHLQPNYVPMPFRTRVVNSARIMDYLYKDDDEYTHVGELMKGSVAALLIDPA
What is the function of this protein?
Probable sesquiterpene synthase.
What are the official names of this protein?
Probable terpene synthase 2, RcSeTPS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: AGO1_HUMAN
Sequence: MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi).  Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them.  Lacks endonuclease activity and does not appear to cleave target mRNAs.  Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
What are the official names of this protein?
Protein argonaute-1, Argonaute1, hAgo1, Argonaute RISC catalytic component 1, Eukaryotic translation initiation factor 2C 1, eIF-2C 1, eIF2C 1, Putative RNA-binding protein Q99.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: HIS3_RHOE4
Sequence: MSLDPAIAAKLKRNDAGLFSAVAQEKSTGDVLMVAWMDDEALARTLETRKGTYYSRSRQQYWVKGETSGHTQYVHEVRLDCDGDSVLLIVDQEGAACHTGTHTCFDTDVLLAAEQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRII_STRGR
Sequence: MAPNAPFARSLRLQRLHHHDPDRLFIVPLDHSITDGPLSRAHRLDPLVGELASHHVDGIVLHKGSLRHVDPEWFTRTSLIVHLSASTVHAPDPNAKYLVSSVEESLRMGADAVSVHVNLGSEGERHQIADMAAVAEACDRWNVPLLAMMYPRGPKIDDPRDPALVAHAVQVAVDLGADLVKTLYVGSVAAMAEITAASPVPVVVVGGPRDSDESRILAYVDDALRGGAAGVAMGRNVFQAPDPGAMADKLSDLIHNSGTRGAARAPAGAAAGAA
What is the function of this protein?
Catalyzes aldol condensation between L-aspartate-4-semialdehyde (ASA) and dihydroxyacetone phosphate (DHAP), to form 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate.
What are the official names of this protein?
2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. GriI subfamily.
Protein: RL18_THEPA
Sequence: MGIDLVKAGRVKKPGRKALVSKNPYLRLLVKLYKFLSRRTDHSFNKVVLKRLLMPRRFKAPLSLSKLSKHMEKRPDNTAVVVGTVTNDERMDVVPKLSVCALRVTETARKRILASGGEVLTFDQLVARSPTGSRCTLLRGATKAREAVKHFRNEVKGNPKPYVRSKGRKFEKARGRRHSRAFKV
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_MICAN
Sequence: MDLKSLIRDIPDFPKPGIVFRDITTLLNHPQGLRYTIDTLTAKCRDYGLSPDYIVGMESRGFLFGVPLAYQLEAGFIPVRKPGKLPAAVHSIEYDLEYGSDSLEIHQDAVASHHKVLIVDDLIATGGTAKATAGLLEKIGCEVLGFAFIIELIDLGGREKLPDLPIITLIDY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYPD6_RAT
Sequence: MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNDTDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL
What is the function of this protein?
Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain (PubMed:27344019).  Inhibits nicotine-induced Ca(2+) influx through nAChRs (By similarity).  In vitro, specifically inhibits alpha-3:beta-4 and alpha-7 nAChR currents in an allosteric manner (By similarity).  Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity).
What are the official names of this protein?
Ly6/PLAUR domain-containing protein 6.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Membrane. Cell membrane; Lipid-anchor, GPI-anchor. Synapse, synaptosome. Membrane raft.