PharMolix/UniProtQA huggingface dataset:
Protein: PYRD_YERPG
Sequence: MYYPLVRKALFQLDPERAHELTFRQLKRVSGTPLEFLVRQSVPTKPVSCMGLSFKNPVGLAAGLDKDGECIDALGAMGFGFIEVGTVTPRPQVGNDKPRLFRIVEAEGLINRMGFNNHGVDNLIENVKKSHFGGILGINIGKNKDTPVEQGKEDYLICMDKIYPYAGYIAINISSPNTPGLRSLQYGEALDDLLAAIKDKQTELHQRHHKYVPVAVKIAPDLTEEELIQIADSLVRHNIDGVIATNTTLDRSLIQGLNYCEQAGGLSGRPLQLRSTEVIHRLSQELKGRLPIIGVGGIDSVTAAREKMAAGASLIQIYSGFIFRGPGLIKNIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYT_DEIRA
Sequence: MHVTLPDGKQLDLQPGATALDAAKAIGPRLAQDALGATANGELTDLMTPLSDGASITLITKKNPGDAAPLFRHSLGHVMSQAVGEYYKAKGYGPDAIKRGVGPYIENGWYQDFDLPEPLKEEDLPEIEKIMRDIIGRGLDITRREISKDEALAQFPHDPYKAELIEGLPDDEPITFYSQGDYTDLCRGPHFPSTGKLPQSFKLMSTSGAYWRGNEKNPILQRIYGVAFATQKELDEYLFQLEEAKRRDHRKLGKELELFTIDPLVGKGLPLWLPNGTVLREELTNFMKEQQFQRGYQGVVTPNIGNLDLYRTSGHYPYYSESQFNPIQVDEEEYMLKPMNCPHHVRIYASKPRSYRDLPVRLAEFGTVYRYEQSGELNGLTRVRGFTQDDAHIFCRPDQLKREFLDVLDLTVLVLKTFGMTDVRFRVGVRDPESDKYVGDEQNWALAERQIIEAVEEVGLPYTIEPGDAAFYGPKLDFVVKDVLGREWQLGTIQVDYNLPERFDISYTGEDGQEHRPIMIHRAPFGSIERFTGILIEHYAGDFPLWLAPRQVMIIPIADRHNAYAEELREELHRAGLRAEVDDSSNRMQAKVRDAELHKIPVMLIVGDKEQEAREVSVRERTGEGTKERKGVKFDELKAELLERRKNRS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ECOBW
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_PROMT
Sequence: MQTTELVRFKKLGKQISVLTAWDAISSSIVEAAGADVVLVGDSLGMVVLGHSTTLPVTLDQMLHHTKAVCRGFCKPLSKQPLVVCDLPFLSYQCGEDKAVEAAGTLLKNSTASAVKLEGAEPETLLVIKRLIRMGIPVMGHLGLTPQSVHQLGYKSQARDKDSQEKIFKDSKMLQESGCFAIVLEHIPGEIASRLKKHIDIPVIGIGAGNDCDGQVRVTADILGLSIAQPPFAKPLLAGRELCINALKEWINSTDLDQVNPTTKTSESKSDC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_RICAE
Sequence: MSKPTREEATEAVRTLLKFIGEDPSREGLLQTPDRVINSYVEIFSGYGKDVAEILNTKFYETCNFQDFILLNIKFTSFCEHHILPFNGTVDIAYIPDNCIVGISKLARIVNIFARRLQIQEKMTVQIAESVQENLKPLGVAVKISAVHSCMSMRGVMQDNSVMNTMHYTGIFAEQQKYRHEFLNLTAKR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TRPF_SYNAS
Sequence: MTEIKFCGMTRLSDALVAAENGANALGFIFYPRSPRYLPPEKARELIRRLPPEVIRVGVFVNEAVEKVKEIYHICGLDLVQLHGDENPDYCRRFPAPMLIRAVSPRNGADLAVLDRYSCRAFLLDRREGALYGGTGGISNWELGRRIRERFPLILAGGLNPENVMTAIENVLPHAVDINSGVESAPGIKDPEKIRAVLAAVRRYQGIRETEEERKEPERFRIFERTDEKI
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: PDXT_AERPE
Sequence: MRIGVLGYQGGVYEHVYMLRRTFDRLGVHGEAVVVKKPEDLKGLDGVIIPGGESTTIGILAKRLGVLEPLREQVLNGLPAMGTCAGAIILAGKVRDKVVGEKSQPLLGVMRVEVVRNFFGRQRESFEADLEIEGLDGRFRGVFIRSPAITAAESPARIISWLDYNGQRVGVAAVQGPLLATSFHPELTGDTRLHELWLRLVKR
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SYA_PROM1
Sequence: MEKSSSSSINPPSLSGDEIREAFINFFVQHNHQKLASSSLIPDDPTVLLTIAGMLPFKPIFLGLKESSTPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKKEAIQWAWELSTEVFRLNPQNIVISVFKEDLEAEQIWKEVVGVDANRIIRMGAADNFWSSGATGPCGPCSELYFDFKPELGSDEIDLEDDSRFIEFYNLVFMQYNRDLEGNLEPLANCHIDTGMGLERMAQILQKKSNNYETDLIFPLIKAAALLAQLEYETTNKKNKTSLKIIGDHCRAVTHLICDGVSASNLGRGYILRRLIRRMIRHGRLVGIVQPFLPQLAEMAIELMKNAYPQLLEKKKIILNELKIEESRFLETLERGEKLLAEITSHECDLISGAQAFELYDTYGFPLELTEEIANEKGISVDINGFENEMAKQRKRAKEASVSIDLTEEGSIEREISLFDETRFEGYEKLETTSTVIGIFKNNESVKQAVQGDLVKIIVNRTPFYAESGGQIGDKGIITSQDLEVSVENVRKKKNIFIHSGIVNTGVLEINSSVQMNVTPSFRQRTTSNHTATHLLQSALKLSIDSSVSQRGSLVSNHRLRFDFNAPKPLTIKELEDMEVRINQWINEDHPIQIKTMPIKEAMAAGALAMFGEKYGDVVRVVDVPGVSMELCGGTHVTRTSQLGTFKIINETGIASGIRRIEAIAGPSVLDYFNERDLVVKELSKSFKVQSYEIVERVSSLQLELKDKTKELIKVKNDLALAKALGLASYAKSVGKSKLLIRRLDGVDGSGLQSAASSLIDHLGKYSAVIFGGIPNQEIDNKLVFVAAFSPDLVSDGLHAGKFISGVAKMCGGGGGGRPNLAQAGGSQPQSLDLALEKANENLTQQLS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_ECOBW
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RSGI_BACAN
Sequence: MMNKGIVMDIKKHSVVVLTPNGEFITCKRKGDSCMIGEEISFDEQEQKASRFSIPYFLKPASLLVACFLCALLFFYNQPEEKVFAYVSVDINPSLEVSVTKDLRVIDLQACNDDGRRILKELKQWENKQLQEVIRTIIKQSQEDKYLTNDKQVMLTAIAKDKLLEPKLEKVMKELKKEYELKHITVEYQSSTMQVRENAIKAGIGTGVYIKQENEKNKSVTPPATPSNPVENEEERQSQPDSSPDVVPDLSSVKDKKYEKPEYKEQKKIEEQPTKQIKENNGRGSQQENRGNQQENNGRESQQGNNGNQQGNNGRESQQGNNGNQQGNNGRGSQGNNGHQQENNGRGSQGNNGNQQGNNGRGSQGNNGHQQENNGRGSQGNNGNQQGDNGRGSQQGNNGNQQGDNGRGSQKENVGNEQGNNGRGSQQENRGHQQGNEKKNQ
What is the function of this protein?
Anti-sigma factor for SigI.  Negatively regulates SigI activity through direct interaction.  Has no direct effect on virulence gene expression.
What are the official names of this protein?
Anti-sigma-I factor RsgI.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: REST_RAT
Sequence: MATQVMGQSSGGGSLFNNSGNMGMALPNDMYDLHDLSKAELAAPQLIMLANVALTGEVNGSCCDYLVGEERQMAELMPVGDNHFSDSEGEGLEESAELKGDPSGLDNMELRSLELSVVEPQPVFEASAAPEVYSSNKDPAPEAPVAEDKCKNLKAKPFRCKPCQYEAESEEQFVHHIRVHSAKKFFVEESAEKQAKARESGASPSEEGEFSKGPIRCDRCGYNTNRYDHYTAHLKHHLRAGDNERVYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCSKCNYFSTEKNNYVQHVRTHTGERPYKCELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCNYVASNQHEVTRHARQVHNGPKPLNCPHCDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPSKTMDVSKVKLKKTKRREADLHRDAAAAATEQTDTEQAKTKGVDASARRSERPVKGVGKDVPKEKKPCSNASVVQVTTRTRKSAVETKAAEGKHTDGQTGNNAEKSSKAKKSKRKMDAEAHPSVEPVTEGPVTKKKKTESKPKTSGEVPKGSRVEDRKADKQQSASIKKGGKKTALKTKTAKKGSKLAPKWVGHTEPSSEMAQGGESPVPALTQAVVTPSGSTQTELSSPMDIAQTEPAQMDVSQTGPPQVQRPLPVEPAQLEPSPPQEPPQVEPPACVEPPPPVEPPCPMEPAEMEPSPPMEPSQVEPPPHLEPPLPMELPQVELPPVEDCQKELPPVEHAQTKVAQTGPTQVGAVQEEPLFCLRATSSQANQKVISPKDRAKEKLSVLSEMARQEQVLIEVGLVPVRDSQLLKASKSAPDLPAPPSPLPKGHLRREETPKDQEMFSDGEGNKVSPLEKGGTEEAGESRAELAAPMESTSALSSEQSSNAPDGETLHSECQADSTAVCEMEVDTEQKTDRVPLKDSAVEPVSPLNPRVDPEAAAPAVVASPPITLAESQEIDEDEGIHSHDGSDLSDNMSEGSDDSGLHGARPAPQEATSKSGKEGLAVKVTEGEFVCIFCDRSFRKEKDYSKHLNRHLVNVYFLEEAAEEQE
What is the function of this protein?
Binds to the 3' region of the neuron-restrictive silencer element (NRSE), with lower affinity than full-length REST isoform 1 (By similarity).  Exhibits weaker repressor activity compared to isoform 1 (By similarity).  May negatively regulate the repressor activity of isoform 1 by binding to isoform 1, thereby preventing its binding to NRSE and leading to derepression of target genes (By similarity).  However, in another study, does not appear to be implicated in repressor activity of a NRSE motif-containing reporter construct nor in inhibitory activity on the isoform 1 transcriptional repressor activity (By similarity).  Post-transcriptional inactivation of REST by SRRM4-dependent alternative splicing into isoform 6 is required in mechanosensory hair cells in the inner ear for derepression of neuronal genes and hearing (By similarity).
What are the official names of this protein?
RE1-silencing transcription factor, Neural-restrictive silencer factor.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with ZFP90 in the nucleus (By similarity). In response to hypoxia, there is a more pronounced increase in levels in the nucleus as compared to the cytoplasm (By similarity). In aging neurons, increased levels in the nucleus as compared to the cytoplasm (By similarity). SUBCELLULAR LOCATION: [Isoform 6]: Nucleus.
Protein: CTR1_CRYNH
Sequence: MDMSGMDGMDHMSSTSSNMSMSMKMYFHGTIGGDLLWFASWMPSSAGATVGVCIGLFILAIFERYLVAFRRACDAAWRRGQVGYVRPCSNGPLVFSSGKSTSLPPPVLFNRRSSTKKEKDVYNPLTPSDYALESNQDGSVEPVTPYTPSIHALRESQEGSSAPSYAHSQQGQAQAQGSGVGCDPCAEGRVAEIERCKEKAVERGLVHSHLPKAVRRSLDPGREGRWSRPFRLAVDVPRGLLQALQTLIHYLLMLVVMTFNIWWMISVVIGCGVGEMLFGRFGSSHVGH
What is the function of this protein?
High affinity copper transporter involved in Cu(+) import into the cell upon copper-limitating conditions (PubMed:21819456, PubMed:23498952, PubMed:31932719).  Functions with BIM1 and probably also FRE4 and FRE7, where FRE4 and FRE7 metalloreductases liberate the Cu(2+) bound to the BIM1 copper-binding site for subsequent import of Cu(+) into the cell by CTR1, via the reduction of BIM1-bound Cu(2+) to Cu(+) to reduce binding affinity for BIM1 but increase affinity for CTR1 (Probable).  The BIM1-CTR1 pathway for copper uptake plays a key role in colonization in the brain where copper amounts are low and thus in cryptococcal meningitis (PubMed:25417972, PubMed:31932719).
What are the official names of this protein?
CUF1-dependent copper transporter 1, Copper transporter 1.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS8_AERS4
Sequence: MSIANLARRVVRALTPYQSARRIGGKGHVWLNANEAPQAYPFTIEGNRLNRYPECQPAEVVNGYAAYAGVNPDQVLVSRGADEAIELLIRTFCEAGEDQILICPPTYGMYAISAETCGVGIVEQPLTACRQPDWPAIADRLSDVKLVFLCSPNNPTGDLVGRDGLIALLEKARNRAIIVVDEAYIEFCPKASVVDLLARFPNLVVTRTLSKAFALAGIRCGFTLASTEVIAMLAKVIAPYPIPDPIAQIAAQALSPMGLELMQERVAELNKQKALIKTALTALPCVREVFEDKGNFILVRFVDSAAVFAAMKAAGIILRDFSTKPGLENSIRITIGYQNKMDAVLAVLRDQPVSL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CSAG1_HUMAN
Sequence: MSATTACWPAFTVLGEARGDQVDWSRLYRDTGLVKMSRKPRASSPFSNNHPSTPKRFPRQPRREKGPVKEVPGTKGSP
What is the function of this protein?
May play an important role in maintaining centrosome integrity during mitosis.
What are the official names of this protein?
Chondrosarcoma-associated gene 1 protein, Cancer/testis antigen 24.1, CT24.1, Cancer/testis antigen CSAGE.
Protein: RNFB_METAC
Sequence: MSSVLINSIAVLAGLGFAVGVMLVIASKVFKIDSNPLIDDVASLLPGANCGGCGFAGCAACAEAIVEQGAPVNSCPVGGFEVAKQIGALLGQEVTESEKEFPFVRCQGGNQHCTTLYDYHGVENCKVALMLCDSRKGCTYGCLGLGTCVQACQFGALSMGEDGFPVVNKALCTSCGNCIAACPNGVLTFARDSEKVHVLCRSHDKGKDVKAVCEVGCIGCKKCEKECPAGAIRVTEFLAEIDQEKCTACGACVAICPQKAIELR
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Catalyzes Na(+) transport, most probably coupled to electron transfer from reduced ferredoxin to methanophenazine and heterodisulfide reductase.  Involved in heterodisulfide reduction during methanogenesis from acetate.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ENO_BUCBP
Sequence: MSKIKKIISREIIDSRGYPTIESEVHLQNGSIGLASIPSGASTGSREALELRDNDPLRYFGKGVKTAVSIVNTSISSAIYNQDAYDQENIDKIMINLDGTKNKSKIGANSILSVSIATAKAAAQSKKIPLYQYISELHGIKEELLMPLPMMNIINGGKHADNNIDIQEFMIQPIKANTIKEAIQIGAEVFYTLGLILKRRGFNTTVGDEGGYAPNLKSNESAFLILSEAVSQSGYMLGKDITFCIDCAASELYNSKTKTYKLTSEQKKFTSYEFTNYLSALVDKYPITSIEDGLDESDWNGFKYQTKKLGKKIQLVGDDLFVTNTNILKKGIQNNIANTILIKLNQIGTLTETLNAIKLAQNSNYNTVISHRSGETEDTTISDLAVGTNSGQIKTGSVCRSERTAKYNQLIRIEEKLGAKTKIFKNFYFNI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AROC_COLP3
Sequence: MSGNTFGKLFTVTSFGESHGLGLGAIIDGCPPGLELTEADLQIDLDRRRPGTSRYTTARREADEVKILSGVFEGKTTGTPIGLMIENTDQRSKDYGNIADSFRPGHADYTYWQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGMTIQACVTQIGDIVASGPKGAPFDVNTVDWSSVEDNPFFFPDETKIEQLGEYLRDIIKEKDSIGAKVTVVATNVPVGLGEPIFDRLDADIAHGLMSINAVKGVEVGDGFAVVNQKGSEHRDELTPEGFSTNHSGGVLGGISSGQQIIAHLALKPTSSIGVSGKTVNLTGEATDIITKGRHDPCVGIRAVPIAEAMLALTLMDHFLRHRGQNADVQCNTPDIEA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: XLNR_EMENI
Sequence: MSTTSLQQFATATSFSPFSNSQSARMSQSQSQTIGLDTLAEGSQYVLEQLQLSREGGNSENNSTFKPSSVRDSLAEARSMIRKNSSSAPVRRRISRACDQCNQLRTKCDGQNPCAHCIEFGLTCEYARERKKRGKASKKDIAAAAAAAGHQGGMGNRSPTDRRLSQEPGGRYDSVLEASRVQSHLPANGLSSIHNTQAAHSQPPLGSALDALHLNHFTQLNESGRSQMPVSDLRSLQILHNNPRSPSALPHGLNAYNDNTFSLLNSQEPNTTSLNHFRLGNSTDNPSAQFLGLSPPAQSPGWLPLPSPSPANFPSFPMAPFSGTSLRYPVLQPVLPHIASIIPQSLACDLLDLYFTSSSSSHLSPQSPYVVGYIFRKQSFLHPTKPRVCSPGLLASMLWVGAQTSDAPFLTSPPSARGRVCQKLLELTIGLLRPLIHGPALGEASPNYAANMVINGVALGGFGVSMDQLGAQSTATGAVDDVATYVHLATVVSASEYKAASMRWWTAAWSLARELKLGRELPPNASQPGQDGERENEGDNPSKRNQSLHGGNSNVNVTEEEREERRRLWWLLYATDRHLALCYNRPLTLLDKECSQLLQPMNDDLWQAGDFPAATYRAVGPPIECTGHSMFGYFLPLMTILGGIIDLQQAREHPRYGLTFRSGPDLDQYIMAITQQLDAYGQSLKDFEARYINSLALAENEPPENPHIDHLSPSGRSSSTVGSRVNESIVHTKMVVAYGTHIMHVLYVLLAGKWDPINLLEDHDMWISSESFLAAMSHAVGAAEAAADILEYDPDLSFMPFFFGIYLLQGSFLLLLAADKLQGDANPSVVRACETIVRAHEACVVTLNTEYQRTFRKVMRSALAQVRGRVPDDFGEQQQRRREVLSLYRWTGDGTGLALS
What is the function of this protein?
Transcriptional activator of the xylanolytic system.  Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose.  Binds to the DNA sequence 5'-GGNTAAA-3'.
What are the official names of this protein?
Xylanolytic transcriptional activator xlnR, Xylanase regulator.
What is the protein family that this protein belongs to?
Belongs to the xlnR/xlr1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NT5M_HUMAN
Sequence: MIRLGGWCARRLCSAAVPAGRRGAAGGLGLAGGRALRVLVDMDGVLADFEGGFLRKFRARFPDQPFIALEDRRGFWVSEQYGRLRPGLSEKAISIWESKNFFFELEPLPGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQPPRRRLHSWADDWKAILDSKRPC
What is the function of this protein?
Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP.  Has only marginal activity towards dIMP and dGMP.
What are the official names of this protein?
5'(3')-deoxyribonucleotidase, mitochondrial, 5',3'-nucleotidase, mitochondrial, Deoxy-5'-nucleotidase 2, dNT-2.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TMCAL_BACHK
Sequence: MQQTKKLTHSDITIAVMSGPFLQRGEPALVSKWYRTKMALACGVDLVVELPYAFSTQKAETFANGAISILNALHVSEICFGSEDGQIENFYNTISVQKNEEETFNRLVKQFMNAGNSYAKATSEAFLHILSSEKNIDMSQPNNILGFQYIKAILMQNSSMQAQTIKRFASHYHDETFNDQHIASATSIRKQLFSENSSFTEIESFIPKATASLLASYKQNYGTLHNWEQYFSFFKYKLMTMSPEDLRHIYEIEEGLEHRILSKIQTSSSFHSFMESLKTKRYTWTRLQRACTHILTNTTKEEIYCANIEQHAPYIRLLGMSQKGQTYLSKNKKKIELPILTHTKTFDHPTLHIERKANSVYFSIMKEPLRTQLLKRDATHHPIRYDETTAKFL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STAAS
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: OTU3_ARATH
Sequence: MELKSSSNNNILEQLRNGFARFELVSSPTASVSDSISSTSLPASFISTTKGNSYVFFARINSSMNRSPAAKKVEKYAVDRVKGDGRCLFRALVKGMAFNKGITLNPQRERDDADELRMAVKEVICNDPKEREKYKEALVAITVDESLKRFCQRIGRHDFWGGESELLVLSKLCKQPIIVYIPEHEHGRGGGYGPGFIPIQEYGSEFRGGWGKGKTNKNVVRLLYSGRNHYDLLR
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (PubMed:24659992).  Cysteine protease with a preference for 'Lys-63' over 'Lys-48' over 'Met-1' -linked ubiquitin (UB) tetramers (e. g.  Ub3 and Ub4) as substrates (PubMed:24659992).  Cleaves also RUB-GST fusion (PubMed:24659992).
What are the official names of this protein?
OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 3, OTU domain-containing protein 3, Deubiquitinating enzyme OTU3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.
Protein: NADK_RALSO
Sequence: MTSRANATSPFKTVALVGRYSAANIAAPLLELASCIAARGHDIVFERETALNIGVQDYPALPPDEMARHADVAVVLGGDGTLLGIGRHLAGASVPVIGVNHGRLGFMTDIPFEDVHNVLPDMLAGQYEAETRSLLQAQVVRDDETIFSALAFNDVVVNRSGFSGMVELAVSVDGFFMYNQRSDGLIVSTPTGSTAYALSAGGPILHPALSGLVLVPIAPHALSNRPIVIPHDAEVVIQVTSGRDASVNFDMQSLTSLLPGDRIVVRRSERTVRLLHPVGYNYYATLRKKLHWHEYPTEDNRL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_AGRFC
Sequence: MSLRLKLHNTLTREKSEFAPIDADNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEDHVTYARNITDLDDKINARALRDYPHLPLNDAIHAVTKKTADQFHDDVAALGCLQPTVEPRATDYIAEMIYLIERLIERGHAYKAGGEVLFDTRSMADYGQLSKRPLDEQQAGARVAVEAHKKNPGDFVLWKLSSESEPGWESPWGLGRPGWHIECSAMAGRYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTHVMANVWMHNGFVQVEGRKMSKSEGNFVTIYELLHTDKFGGRQWPGEVLRLAMLMTHYREPIDFSVKRLEEAERLLSKWPAAETSDAAADETVLEALADDLNTVAAVQALHALAHAANTDPSRLPAFAASAALLGVLPKKTEMDEAIVSAVDALVELRLEMLKAKNFAEADRLRDELSEKGIQLKDGKDKETGERTTTWELKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_LACP7
Sequence: MARDMSPVLKRCRALGLEPTFLGIDKKSNRNFARAGKKISEYGTQLREKQKAKFIYGVLEKPFRNNFDKAKKLKYGTTGENLLILLELRLDNVMFRMGYGRTRTEARQIVDHKHVLVNGKCVNIPSYQVKAGDVISIKEKCKSAQRYKDILEVTDGRTVPAWLEADHENLTGTVKEIPTRDQIDVPVNEVLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.