PharMolix/UniProtQA huggingface dataset:
Protein: SYV_SHISS
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR785_MIMIV
Sequence: MVKIEIYYYQKKFDTDNEHAFIFGSKSYTKVYEYTDDTQTNYKDILELIFEKFNNTDNPLKSLDNQKIIRNNKLHTSMSVDDIVKIDNNYYIVDIIGFKSINTNDINQ
What are the official names of this protein?
Uncharacterized protein R785.
Protein: SKP1_MACFA
Sequence: MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.  In the SCF complex, serves as an adapter that links the F-box protein to CUL1.  The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.  SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.  SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.  SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.  SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.  SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1.  SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.  SCF(FBXW2) directs ubiquitination of GCM1.  SCF(FBXO32) directs ubiquitination of MYOD1.  SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5.  SCF(FBXO33) directs ubiquitination of YBX1.  SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53.  SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription.  SCF(CCNF) directs ubiquitination of CCP110.  SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2.  SCF(FBXO9) directs ubiquitination of TTI1 and TELO2.  SCF(FBXO10) directs ubiquitination of BCL2.
What are the official names of this protein?
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: SYK_COXBN
Sequence: MELKDQIKEENEQIAQRKLKLKKRREEGQAYPNDFKRDSLAADLHAVYDQFDSGALTAKAIRVKMAGRMMTRRIMGKASFAHIQDMKGRMQIYVTRDSLPQGVYSDFKSWDLGDIVGIEGELFKTKTEELSVKVDQIRLLTKALRPMPDKFHGLHDQEQRFRQRYLDLIVNESSRHLFQTRSQVIAQIRRFLDDRGYIEVETPMMHPLPGGAAARPFETHHNAMNMDLFLRIAPELYLKRLVVGGFEKVYEINRNFRNEGISTRHNPEFTMLEFYQAYATYEDMMMLTESMIRHLAEKIFGVMEIKYQGVRIDLNKPFPRLSLRDAILQFNPGITPDQIDHLETARELAHKYEIATPAHYGLGKIQTELFEKLVEEKLQQPIFITHFPKEVSPLSRANEENDFITDRFEFYVGGREIANGFSELNDPEDQAARFREQLKARNAGDLEAMSFDEDYITALEYGLPPTAGEGIGIDRLVMLFTDNASIRDVILFPLLRSK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALAT1_MOUSE
Sequence: MASQRNDRIQASRNGLKGKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPDFPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVAGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQARDRCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFEEGLFLMADEVYQDNVYAEGSQFHSFKKVLTEMGPPYATQQELASFHSVSKGYMGECGFRGGYVEVVNMDAEVQKQMAKLMSVRLCPPVPGQALMGMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPQIQLPLKAVQRAQDLGLAPDMFFCLCLLEETGICVVPGSGFGQQEGTYHFRMTILPPMEKLRVLLEKLRHFHAKFTHEYS
What is the function of this protein?
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.  Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
What are the official names of this protein?
Alanine aminotransferase 1, ALT1, Glutamate pyruvate transaminase 1, GPT 1, Glutamic--alanine transaminase 1, Glutamic--pyruvic transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR4A5_HUMAN
Sequence: MRQNNNITEFVLLGFSQDPGVQKALFVMFLLTYLVTVVGNLLIVVDIIASPSLGSPMYFFLACLSFIDAAYSTTISPKLIVGLFCDKKTISFQGCMGQLFIDHFFGGAEVFLLVVMACDRYVAICKPLHYLTIMNRQVCFLLLVVAMIGGFVHSAFQIVVYSLPFCGPNVIVHFSCDMHPLLELACTDTYFIGLTVVVNSGAICMVIFNLLLISYGVILSSLKTYSQEKRGKALSTCSSGSTVVVLFFVPCIFIYVRPVSNFPTDKFMTVFYTIITHMLSPLIYTLRNSEMRNAIEKLLGKKLTIFIIGGVSVLM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4A5, Olfactory receptor OR11-111.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAAT2_ARATH
Sequence: MGFLVDTQKEGGGHSWGYVRSLVRRKQVDSANGQSHGHQLARALTVPHLVAIGVGATIGAGVYILVGTVAREHSGPSLALSFLIAGIAAGLSAFCYAELSSRCPSAGSAYHYSYICVGEGVAWIIGWALILEYTIGGSAVARGISPNLALIFGGEDGLPAILARHQIPGLDIVVDPCAAILVFVVTGLLCMGIKESTFAQGIVTAVNVCVLLFVIVAGSYLGFKTGWPGYELPTGFFPFGVDGMFAGSATVFFAFIGFDSVASTAEEVRNPQRDLPIGIGLALLLCCSLYMMVSIVIVGLIPYYAMDPDTPISSAFASHDMQWAVYLITLGAVMALCSALMGALLPQPRILMAMARDGLLPSIFSDINKRTQVPVKATVATGLCAATLAFFMDVSQLAGMVSVGTLLAFTMVAISVLILRYVPPDEQPLPSSLQERIDSVSFICGETTSSGHVGTSDSSHQPLIVNNDALVDVPLIKNQEALGCLVLSEETRRIVAGWSIMFTCVGAFLLSYAASSLSFPGLIRYPLCGVGGCLLLAGLIALSSIDQDDARHTFGHSGGYMCPFVPLLPIICILINMYLLVNLGSATWARVSVWLLIGVIVYVFYGRKNSSLANAVYVTTAHAEEIYREHEGSLA
What is the function of this protein?
Permease involved in the transport of the cationic amino acids.
What are the official names of this protein?
Cationic amino acid transporter 2, vacuolar.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RL19_SHEB8
Sequence: MNNIIKMLNDEQMKQDVPAFGAGDTVVVQVRVKEGDKERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPLIASIEVKRRGRVRRAKLYYLRDRSGKSARIREKLATK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SELO_METC4
Sequence: MTALFPFDNSYARLPSHFFGRVAPTAVEAPRLIRLNRALAVDLGLDPDRLESPEGVEVLAGQRVPEGAEPLAAAYAGHQFGQFVPQLGDGRAILLGEVVGRDGRRDIQLKGSGPTPFSRRGDGRAALGPVLREYLVSEAMHALGIPTTRALAAVTTGEQVIRETALPGAVLTRVASSHIRVGSFQFFAARGDVEGLRALADHAIARHDPEAARADNPYRALLDGVIRRQAALVARWLTVGFIHGVMNTDNMSIAGETIDYGPCAFLDTYDPATAFSSIDRHGRYAYGNQPRIALWNLTRLAEALLPLLSEDETQAVAEAEAALTGFAGQFEAAYHGGLNCKLGLATTRDGDPALAGDLLKTMAENEADFTLTFRRLGEAVPGPDGEPDPAAVEAVRSLFIDPTAYDRWAGGWRRRLKDEAGDAAARRQMMRAANPAFIPRNHRVEEMITAAVERQDFAPFETLLTVLARPYDDQPDFAQYAEPPEGGGRGYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SURE_PHOLL
Sequence: MLRILLSNDDGVTAPGIQVLAAALRENYHVQVVAPDRNRSGASNALTLDRSLSVNTLENGDISVLGGTPTDCVYLGVNRLVLPRPEIVVSGINRGPNLGDDVIYSGTVAAAMEGRHLGLPALAISLNGELHYQTAAEITCRLLQMLQTTPLRAGNILNVNVPDLPLEHIKGFRVTRCGSRHAAEEVYSMQDPKGNMLYWLGPPGDKHDAGPETDFAAVEQGYVSITPLQVDLTAYKAQALVRDWLAKAEVDGEC
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SACD2
Sequence: MPWLQLRINVTPEQAPAVESAALAAGAQAVTLEDNADQPIFEPALGETPLWSDTRITALFEADISTDETWQKVQNHYGEELPHHHWHVLEDKDWEREWIKNYHPIQCGPHFWICPSWLSPPDPNAINLLLDPGLAFGTGTHPTTFMCLEWLAQQDVKNLELIDYGCGSGILGIAGLLMGANSAVGVDIDPQALLATQENAVRNGLAKEAFPVFMPQRAPKEPVDMVLANILAGPLVELAPALIALVKSGGKICLSGVLGTQRTSIISAYEHAIEFTEVREKDEWICLAGIKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMI1_CHICK
Sequence: MSTPNVTARVETWLSSTWHVKVPLTWLEACINWIQEENGGGNLSQAQISRQVFEQWLLTDLRDLEYPILPDGILDAPKGELSGFYSLQIDSLLDVSQPAYSQLQKIRGKSTVNEEVTANTQAFQKPWEAKPTRMLMLQLTDGIHQIQGMEYQPVPVLHSNLPPGTKITVHGNVAYRLGVLLLKPENVKLLGGEVDALLEEYSQERVLARLLGEAENPDSVRQPGHEQIVPGPVDELGQTLGPSDEELLASLDENNDFILNNETSLESGYCSRSNNFSATSCSLTTYNENTTGFPLQQESVNLLPRSDEQTPPSVEYNDAFLNDFPLEDDILLEEEIQRELEEVPSVARNGNVNLSTERIPHTYRSSCGSSLNETSEKDDGCGSEKPVEVTSKQKNLARTVSTGDGTSTGGSLQCNSVSQACSSAIVLLKNPHEERRNDLGPDESSCQSRHAPDSRQLNKDPVSSSKTDPEADQQAILCRPGNACDLDLDSPPFTYISLLLAKKPETITLVKVKCFIVTLTGNLTSSNGSWGIKAKVSDGSAYLEVDFADDILTSLIGFSVPEMHTLRKDPALQPKLKDGLERCQKQLIDLCCLMTIEFNPFQSKATVLILQDTDARHLEQLKKRLNK
What is the function of this protein?
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.  Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution.  Required for BLM phosphorylation during mitosis.  Within the BLM complex, required for BLM and TOP3A stability (By similarity).
What are the official names of this protein?
RecQ-mediated genome instability protein 1.
What is the protein family that this protein belongs to?
Belongs to the RMI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WNT1_PLESK
Sequence: SGSCTVKTCWMRLPTFRTVGDFLKDRFDGASRVIYGNKGSNRASRVELHHLEPENPAHKPPSPHDLVYFEKSPNFCTYSGKTGTAGTAGRSCNSSSPALDGCELLCCGRGYRTRTQRVTERCNCTF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity).  Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity).  Has a role in osteoblast function, bone development and bone homeostasis (By similarity).
What are the official names of this protein?
Protein Wnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ZN137_HUMAN
Sequence: MNVARFLVEKHTLHVIIDFILSKVSNQQSNLAQHQRVYTGEKPYKCNEWGKALSGKSSLFYHQAIHGVGKLCKCNDCHKVFSNATTIANHWRIHNEDRSYKCNKCGKIFRHRSYLAVYQRTHTGEKPYKYHDCGKVFSQASSYAKHRRIHTGEKPHKCDDCGKVLTSRSHLIRHQRIHTGQKSYKCLKCGKVFSLWALHAEHQKIHF
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Putative zinc finger protein 137, Zinc finger protein 137 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: INVA4_PAXIN
Sequence: MNPVAVTSVAPVDIIHDLRHSEHATEASPITLLHVFSRAVSQYPNHELNFITSSAHDSIHTKTFTEFDQYVRALAQAMLAWGKPAGSVIVVYLTEHEDNMAAIWASLFAGYVPCLQPALSAQQAHKEGHVAHIKNLFSSATWLTNESGAEQVQSIPGLDIHLLSELQASAETVSVDFQTHQPHLDDEAILFLTSGSTGFSKAVVHTHRTILAGCNAKGQSYGLTSESKIMNWVGFDHVVGSLGMHITPLLCGASQLHVHASAILSDSLRFLHLIEEKSIQLVFAPNFLLAKLTRDLEKRSDLFGKFDLSSIKRINSGGEAVVSSTAQAFARTLKNLAKDGDASFVFSTGFGMTETGAGCIYDTIDVLGTSPPHEFLEIGTPVAGCEMRIVNPEDGVTPRPDGESGELQVRGPMVFVRYYNNPETTSSSFVEGGWYRTGDVGIFEKGKMRLSGRIKDTVVVHGVSYGIPELETYLQTVEGVAHSFLVAAPYRAPGQETEGFVVFYSPTFDLDSEDAPAKLYATHRALRDVSVKLITLPPQQIIPLTLNQMEKSTLGKLSRARLLNLFKQGELAKYIIRAEELLGIARGANFVAPSTETEKTLAGIYAGIFHLSVSDISTSENFFEFGGTSIDAIRLKREAESAFDLSEIPTIQIFKHPEIITLAKYVDSLVSKDASEEEYDPIVPLQLTGKKTPIFMVHPGIGEVLIFVNLAKYFQNERPFYALRARGFEAGQPCFTSLDEMVSCYAAAIKRTQPHGPYAIAGYSYGGVIAFEVAKRLEVMGSEVQFTGIIDMIPHHMPRSDWTGGLLILSYFLGLVSKQDTNDLAPSMRPLARTEQFEMVWKLSPPERLVELQLTLEKLEHWVNVADSVREFAKKYEACSSVSVLDVFYAIPVRGTKEDWFNNHIKRWASYSRAEPSYVDVPGHHYTLMDFDHVPRFQKIFRARLEARGL
What is the function of this protein?
Inactive atromentin synthetase homolog.  Does not accept 4-hydroxyphenylpyruvate (4-HPP) as substrate.
What are the official names of this protein?
Inactive atromentin synthetase invA4, Nonribosomal peptide synthase-like enzyme invA4, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ACP_HAEIG
Sequence: MSIEERVKKIIVEQLGVKEEDVKPEASFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKITTVQSAIDYVQNNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SALA4
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWLEMHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESVLAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: HUTH_STAA3
Sequence: MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVERIIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHDVHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGVEGLSPKTRRKYDEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_FINM2
Sequence: MELNKYIDHTLLKADATSADIKKICDEAIKYDFKSVCVNSCYTSLVKKSLENSSALVCTVVGFPLGAMSTKSKAFEAKTAIEDGADEIDMVINIGKLKEKDYDYVEKDIQAVRDATKGKVLKVIIETCLLTDEEKKKACEISVKCGADFVKTSTGFSTGGAKVEDVKLMKDTVADKAMVKASGGIHSREEALAMIENGADRIGASSGIKIVEG
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN1_MAGO7
Sequence: MYSNSNSFLGGGNSMRPGPQQYGSSFNAGSGQQQQQQQQQQQPPQQSPFAAQQTGFAQVPLQHQYTGYPAMQQPMQTGQIQPQYTGFPGHQQGFQGSAPPMPAIPQQFQHQFQHQQQQQQPPPQPQQSASFLSSQPTTSSSLQTPSAPAAAMKPQPTGFSQMAASFQTGGQSAPKPAQASKGTKIPNIRLSFITAQDQAKFETLFKSAVGDGQTTMSGEKARDILMRSRLDGEYLSQIWTLADTTRSGQLHFPEFALAMYLCNLKMNGKSLPSSLPENIKNEVSSMVDIINFSIAEDSANASSATNAPDFTVRQNTATPPTIQHPQPQPSNSQLLQAQMTGFPGAQQGFMAQANGGGLQPQQTGYPGMQNPQPTGYTGPRPPMPPMPTGLGAGGMGAMAAPLNAQPTGRPGQWGLVNTPSTGLPNIDALHARMMPQQGREQGSFTTAGLQGNAVIPWAITKDEKTRYDALFKAWDGMNKGYIAGSQAIEIFGQSGLEKPDLERVWTLADHGNKGRLNLDEFAVAMHLIYRKLNGYPLPNSLPPELVPPSTRNFNEAIGTMKNMLNQESDFRKNSGAALLPQKTGVSYLKTHSFRGQGGVPTGSRKDATVFKNDDDAVGYKSSARRRIGNGSPRPDSPSSVASNEDLSIEQLRKKIKEKQVLLDAMDFKDEKSFEEDDVLDRRDRKEAEDLYRRIRRIQEDIDSHPDAPLPSGDSDAERRALKRQLQNLKDSIPDLASQVRKTEKAIFEARLELFRLKDAKAHPSSAPAIVGTGPGGAVTESDRLKARAKAMMQQRTAALTGKKIDISSEDTDAPKRLEEESIQARTEKENNERMVRDVEESVQEFARSIEDSLQAGGQTADNEHERRRWEDALGVEDEIRDFIFDLQRSSRSKRVRAQDRRADRSGPTSDPPRSEPASAPRHESPSAPAARTGTPTSASSAGGSYSSYKTPEERAAFIKQQAEQRMAERLAALGIKAPVKGGETPAQRMERERSERAAKLRQAEEEDARREAERQARLAEEQGPPQPAASAPKTEAKPPPPPPSRKAAPDRETAAKKAEEERLAQEQEEQQRQMREMEAKAKAEEDALARENSAAEARLKALEEQVRQGKLKKEEEKRRKKAALAEAKEKEAKLAARRQEIEAAKRREEELQRQLEAMNEEGSSSDDDEPAQITPQASTPTVGSQELERKPSPPPQVAEPKTESRNPYFRMLSQSSEGPTSVSPQASVSPVPQQEAPAPAPPPAAPEASTNPFHRMTAPQTAAPAPISRKRADTDDGWGSDKDDDEDDSDDDRPGGTSAAQLASILFGTMGPPRPLSAADNKSVSSPTAVASPPTVASPPPAPPGPPPVPAAAAPTVPSTPSPAPEITSAPPAPPPPPPPMPSMGAPGAPPPPPPMPPTGAPSAPPPPPPPPPAASSSSAPAATPAGGRPAGFLGEIQAGRALRKTTTKDKSAAAVAGRVLD
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein PAN1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: CLPX_MANSM
Sequence: MTKETETTCSFCGKSQDEVGKLIAGVDGYICGECIDLCHDLLHDEETREQQSAEEAVETEEKLPTPHEIRAHLDDYVIGQDYAKKVLAVAVYNHYKRLRSNHGIADVELGKSNILLIGPTGSGKTLLAETMARMLNVPFAMADATTLTEAGYVGEDVENVIQKLLQNCDYDTEKAQRGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPQQEMLRVDTSKILFICGGAFAGLDRVVQKRIHKGSGIGFDAEVKGKEDEVSLTDLLKQIETEDLIKYGLIPEFIGRLPVVAPLSELDEKALVQILTEPKNALTKQYQALFGLENVELEFTPEALNAMAKKALERKTGARGLRSIVEGALLDTMYDLPSLEGLVKVVVDEAVINEHSAPKLEY
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HCP_PETMO
Sequence: MEMFCYQCQETLRNEACVAQGVCGKSPETANLQDLLIYVLKGISYWANKARELNVEDESVDLFVAEGLFVTITNVNFDEGRIVEYIDEAVDKRRIIENKFKEVYEKKYNEKFQEKVPDAAVWNPKDNNEDEYLNKAVEVGVLSESDEDIRSLKNFLVIGLKGVAAYTDHAYILKHSNDDILAFIEKALAETLREDITVDELMNLVLKIGEYGVNAMALLDEANTSTFGNPEITQVYTGTYETPAILVSGHDLLDLYEILEQTKGKGIKVYTHGEMLPANAYPGLKKYEHLAGNFGGSWWKQQQEFEDFGGAVVMTTNCIQKPRNSYKDRIFTTGLVGWPDVQHIPNRKKDGQKDFTPVIQKALEIGPIKKREGKAITIGFAHEQTAQVADKIVEAVKSGKITKFYVMGGCDGRNKDREYYTNFAKDLPKSAVILTAGCAKYRYNMLDLGDIDGIPRVIDAGQCNDSYSLVLTALKLKEAFDLKDINELPIEYNIAWYEQKAVTVLLSLLYMGVKGIRLGPTLPAFLSPNVLETVAKTFDIKTI
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_STRPM
Sequence: MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQINNLITERTHPCHKPMRHTSH
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: TF2B_HALVA
Sequence: VEQKEIGRTYRYVAQELELKMEPVDPKQYVPRFASELELSEEVQSKANEIIDTTAEQGLLSGKSPTGYAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQEQIEAMGIH
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) (By similarity).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: DAPB_STRSY
Sequence: MTIKVIIAGFKGKMGSTAVEMVKGDAALSLAALVDPFATETEVDGVPVFKTKEEVASLEADVWVDFTTPKFTYENTRFALENGFAPVVGTTGFTPEEIEELTALSAEKGLGGLIAPNFAIGAILLMQFAAQAAKYFPNLEIIELHHDKKKDAPSGTAVKTAELISQVRQSQTQGAADEEELIAGARGAAFDGFRIHSVRLPGLVAHQEVIFGAQGEGLTIRHDSYDRISFMGGVNLGIKEVVKRSQLVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.