PharMolix/UniProtQA huggingface dataset:
Protein: METE_BLOPB
Sequence: MTIVGHILGFPRIGLHRELKYALEYYWDGKIKEDKLLEIGRTLRIRHWKQQKDSGIDWISVGDFAWYDHVLTTSLMLNNIPDRHRIGQENINLNTLFRISRGYSLDKKLIPPSEMKKWFNTNYHYIVPEFVPNQEFKLNWTQLFDEIDEALSLKYTVKPILLGPISYLWLGKIKGKKFDRLSLLPNLLSVYQEILDILLSKNIDWIQIDEPILVLELPLQWLNAYLSAYEQLHGKVKLLLTTYFDSIYHQLDIITRLKIDGLHVDLVSNPDNIPLLHARLPKHWTLSAGVVNGRNVWKTNLHDWFKKLYPLVGERSLWIGSSCSLLHSPIDLNTEIKLDKHIKEWFAFALQKCYEIKMLCAALNAENTSDATYEDTLSEYYISNNLRSYSSTIHNIQVKKRLEHIDEISYSRSSPYTTRVTLQHKKLNLPLFPTTTIGSFPQTEEIRKLRSRFKNNQINKEDYHLNIKNYIKKIIMEQEKLDLDILVHGEPERNDMVEYFGENLNGFIFTQNGWVQSYGSRCVKPPVIIGDISRSKPITIEWISYAQSLTNKPIKGILTGPVTIMSWSFPREDMQRKTIALQLALSIRDEVIDLEKSGIGIIQIDEPALREGLPLKRSDQKQYLEWAINVFRITVSSVKDDTQIHTHMCYSEFSDIIYAILALDADVISIEAARSDEKILKSIRHVIKNLNEIGPGIYDIHSPNKPTQNDLIRRINQLLKYIPEQRLWINPDCGLKTRSWPEIKHSLNNMVSAAKLLRKQFYSS
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: LT_POVM3
Sequence: MDRVLSRADKERLLELLKLPRQLWGDFGRMQQAYKQQSLLLHPDKGGSHALMQELNSLWGTFKTEVYNLRMNLGGTGFQGSPPRTAERGTEESGHSPLHDDYWSFSYGSKYFTREWNDFFRKWDPSYQSPPKTAESSEQPDLFCYEEPLLSPNPSSPTDTPAHTAGRRRNPCVAEPDDSISPDPPRTPVSRKRPRPAGATGGGGGGVHANGGSVFGHPTGGTSTPAHPPPYHSQGGSESMGGSDSSGFAEGSFRSDPRCESENESYSQSCSQSSFNATPPKKAREDPAPSDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPGLHQFEFTDEPEEQKAVDWIMVADFALENNLDDPLLIMGYYLDFAKEVPSCIKCSKEETRLQIHWKNHRKHAENADLFLNCKAQKTICQQAADGVLASRRLKLVECTRSQLLKERLQQSLLRLKELGSSDALLYLAGVAWYQCLLEDFPQTLFKMLKLLTENVPKRRNILFRGPVNSGKTGLAAALISLLGGKSLNINCPADKLAFELGVAQDQFVVCFEDVKGQIALNKQLQPGMGVANLDNLRDYLDGSVKVNLEKKHSNKRSQLFPPCVCTMNEYLLPQTVWARFHMVLDFTCKPHLAQSLEKCEFLQRERIIQSGDTLALLLIWNFTSDVFDPDIQGLVKEVRDQFASECSYSLFCDILCNVQEGDDPLKDICEYS
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GCST_FRATW
Sequence: MLKTPLYESHIAANAKMVDFSGWSMPINYGSQIQEHNNVREDCGIFDVSHMLAVDIQGSEAEKFLRYLLANDVAKLQENKAQYGCMLNHDAGIVDDLITYKVTDEHFRIVVNAGNRESDVAWFNQNAQNFDVAITPQTDLAIVAVQGPKAVAVIKRVVTKEIAAEIEALLPFSFKFFSKWMVARTGYTGEDGFEVILPATQVKKFWDSLLENGAQPAGLGARDTLRLEAGMHLYGADMDTSTTPLERGLGWSVDLSDEHRDFIGKKAYLAKKAQGVDTKWVGVVLKTKGVLRAGQEIDFDNGEKGYITSGSFSPTLKVAIGLAYVPKQADNPVVNIRGKELEVELVKPKFVKNGKSLI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: THYX_TROWT
Sequence: MLQCLFFVMDPVFLSEITVELVKHSASDSDVVFSARVSTLGSFVAVTDCLSNRDIGLITFLMRERHGSPFEHSHMTFRISAPIFVFREFMRHRIASYNEESGRYKNLDPVFYIPDEKRKLVQIGAPGAYKFEEGTSEQYGLLIEEMKELSLAAYDTYKRLLACGIAREVARMILPLNLYSTMYVTINARSLMNFLSVRTSRANSAFHSYPQREIELCADRIEEIWKGLMPETHAAFEKQGRVAP
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: NADE_SODGM
Sequence: MAIQQEIIAALGVKPTIDPAAEFRVSVEFLKAYLKKHIFVRTLVLGISGGQDSTLTGKICQQAISELRQETGIADYQFIAVRLPHGEQKDEADCKDAIAFIEPDRVITINIKSAIQASEATLSEAGIVLSDYVKGNEKARERMKAQYSIAGMTAGLVVGTDHAAEAVTGFFTKYGDGGTDINPLFRLNKRQGRALLQHLGCPEHLYLKAPTADLEEESPALPDETALGVTYEMLDDYLEGKTIDAAAARVIENWYLRTEHKRHPPVTVFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: MOAC_SALPA
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: YL334_MIMIV
Sequence: MGVGFGYTEYTDTFNRKYVNNVINFKKTQIKDSVKTKLSDIISKGYSYNKYIKICKYSVEALEIVKKCLFCKNFLCKIKVFKRIKKHIHVKFFHNDYVDKIKEKFNKLVNKSLKKQINHVCLNSEISLKKKLKVLCLTHNYNIIFEDYGYNFKCKVYGWHVYKKRLDFGNEENVKNGKYCIFTMLEY
What are the official names of this protein?
Uncharacterized protein L334.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L332/L333/L334 family.
Protein: WALR_STAAS
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins (By similarity).  Functions as a transcription regulator by direct binding to promoter regions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y974_RHOBA
Sequence: MKIWIDADAAPRDVKEVVFRAAKRLDVVTILVANAPVGVPANATTVRSVVVREGADQADRYIVSNGEPGDLAVTADLPLAGLLVDKGLFVIDPRGEEYSPATIASRLSMRNFMDDLRGAGVETGGSAPYGPKDKKAFASTFDRLLTKAIRMAETSSE
What are the official names of this protein?
UPF0178 protein RB974.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: PSBA1_PARMW
Sequence: MTTTLQQRSGASSWQAFCEWVTSTNNRLYVGWFGVLMIPTLLAATICFVIAFVAAPPVDIDGIREPVAGSLIYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPFQLVVFHFLIGIYAYMGREWELSYRLGMRPWICVAYSAPVAAASAVFLVYPFGQGSFSDAMPLGISGTFNYMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGVSTMAFNLNGFNFNQSILDGQGRVLNTWADVLNRAGLGMEVMHERNAHNFPLDLAAAESTPVALQAPAIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 1, PSII D1 protein 1, Photosystem II Q(B) protein 1.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PDXH_HALHL
Sequence: MTEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDEQGAVFYTNRASRKGQQLADNPRAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERLSQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPHWSGYRIIPVSIELWSAGDGRLHQRERYEHRTDGWSHFLLNP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: Y255_ARCFU
Sequence: MVLMGEKVRDREHHERLFKASMSPIRRQIVAAIGVQGKTREELKKELELSDFQFKFNLDWLIREGFVKEEDGKLKLTDDGIELLEAG
What are the official names of this protein?
Uncharacterized protein AF_0255.
What is the protein family that this protein belongs to?
To A.fulgidus AF_1348 and AF_1363.
Protein: CCME_LEGPN
Sequence: MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQVLAKHDANYMPPQVKSALADKVKQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: YES_HUMAN
Sequence: MGCIKSKENKSPAIKYRPENTPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL
What is the function of this protein?
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.  Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.  Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.  Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts.  Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration.  Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration.  Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase.  Also involved in G2/M progression and cytokinesis.  Catalyzes phosphorylation of organic cation transporter OCT2 which induces its transport activity (PubMed:26979622).
What are the official names of this protein?
Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, p61-Yes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.
Protein: NRDR_AERS4
Sequence: MHCPFCSAVDTKVIDSRLVAEGHQVRRRRECLLCHERFTTFEMAELVMPRVIKSNGSREPFNEEKLRGGILRALEKRPVSMEAIEKGVNHIKSCLRATGEREVASQLVGNLVMDELKSLDKVAYIRFASVYRSFEDIREFGEEIAKLEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EX7S_CHRVO
Sequence: MAKAAKAPASFETALAQLEDIIQAMDSGDMPLETALASYKQGTELIKFCQGKLADAEQQLKILENNELKTLDLPNGQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP5Z1_HUMAN
Sequence: MFSAGAESLLHQAREIQDEELKKFCSRICKLLQAEDLGPDTLDSLQRLFLIISATKYSRRLEKTCVDLLQATLGLPACPEQLQVLCAAILREMSPSDSLSLAWDHTQNSRQLSLVASVLLAQGDRNEEVRAVGQGVLRALESRQPEGPSLRHLLPVMAKVVVLSPGTLQEDQATLLSKRLVDWLRYASLQQGLPHSGGFFSTPRARQPGPVTEVDGAVATDFFTVLSSGHRFTDDQWLNVQAFSMLRAWLLHSGPEGPGTLDTDDRSEQEGSTLSVISATSSAGRLLPPRERLREVAFEYCQRLIEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRSLSCLKALHGRVRGDPASVRVLLPLAHFFLSHGEAAAVDSEAVYQHLFTRIPVEQFHSPMLAFEFIQFCRDNLHLFSGHLSTLRLSFPNLFKFLAWNSPPLTSEFVALLPALVDAGTALEMLHALLDLPCLTAVLDLQLRSAPAASERPLWDTSLRAPSCLEAFRDPQFQGLFQYLLRPKASGATERLAPLHQLLQPMAGCARVAQCAQAVPTLLQAFFSAVTQVADGSLINQLALLLLGRSDSLYPAPGYAAGVHSVLSSQFLALCTLKPSLVVELARDLLEFLGSVNGLCSRASLVTSVVWAIGEYLSVTYDRRCTVEQINKFFEALEALLFEVTQCRPSAALPRCPPQVVTVLMTTLTKLASRSQDLIPRASLLLSKMRTLAHSPATSSTHSEEGAEAIRTRATELLTLLKMPSVAQFVLTPSTEVCSPRYHRDANTALPLALRTVSRLVEREAGLMPG
What is the function of this protein?
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.  According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair.
What are the official names of this protein?
AP-5 complex subunit zeta-1, Adaptor-related protein complex 5 zeta subunit, Zeta5.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic.
Protein: ATPH_DRIGR
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KATG_BURP0
Sequence: MSNEAKCPFHQAAGNGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGALKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PGPS1_MOUSE
Sequence: MAAPAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRSRERRRRRSPWLLLAPLLSPTVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFELMKGQIKIAKRRVVMASLYLGTGPLEQELVDCLESSLEKSLQAKFPSDLKVSILLDFTRGSRGRKNSRTMLLPLLQRFPERVRVSLFHTPNLRGLLRLLIPERFNETIGLQHIKVYLFDNNVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVEVVDGMVHPYKGDRAAYCRAANKRVMDVIHSARARQQMLHAQTFHSDSLLSQEEAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVFLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFYSEVCSLGQQDRVQLQEYWRRGWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTESRSLQQQLHQEQEQLYLRSGVVTSATFEQPGRQVKLWVKMVTPLIKNFF
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, Phosphatidylglycerophosphate synthase 1, PGP synthase 1, Silencer-associated factor.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS6_KOCRD
Sequence: MGVAVRVIPCLDVDAGRVVKGVNFENLRDAGDPVELAARYDLAGADELTFLDVTASSGERDTMFDVVSRTAETMFVPLTVGGGVRTPQDVDRLLRCGADKASINTAAVERPEVVDEITRRFGSQVLVLSLDARRTGNTASGFEVTTRGGRTLTGLDALQWAREAEERGVGEILLNSMDADGTREGFDLEMISAVREVVGVPLIASGGAGSPEHFPPAVAAGADAVLAASVFHFGPDHAIGDVKAALRAAGHEVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_COXBU
Sequence: MDDYTQSINDAVKCLRQGGVIAYPTEAVYGLGCDPFNHDAVAQLLTIKKRSIKKGFILIASEWKQVEPLTEPIDPKALARVFDTWPGPFTWTFPASKEAPHWITGQHSTIAIRVTAHPLAKLLCQRFAGPLISSSANQEGEPPIRDVKILRLVFGNKIDKILEGPLGPTHRPTPIRDAITGEILRL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1344_SHEB2
Sequence: MESLQNHFLIAMPSLHDTFFERSVIYICEHDAKGAMGLVINKPLGIEVNSLLEQMDLPAEQVSTDLAFNANVMMGGPVSQDRGFVLHTSQPYWANSTDLGCGLMLTTSRDVLTAIGSNRSPEKFLVALGYAGWSKDQLEQELADNSWLTIPATNALLFDIKHEDRWPQASRALGFDAWQVSAQAGHA
What are the official names of this protein?
UPF0301 protein Sbal223_1344.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ACOX2_HUMAN
Sequence: MGSPVHRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYKAAMRRAFHIRLIARRLGWLEDGRELGYAYRALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLCKNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVLPDGTYVKLGTAQSNYLPMVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL
What is the function of this protein?
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (PubMed:27884763).  Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity).
What are the official names of this protein?
Peroxisomal acyl-coenzyme A oxidase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, Trihydroxycoprostanoyl-CoA oxidase, THCA-CoA oxidase, THCCox.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PYRR_BACCZ
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.