PharMolix/UniProtQA huggingface dataset:
Protein: FABA_ACTPJ
Sequence: MNTCTPNIKSSYTYEDLLASGRGELFGKEGPQLPAPTMLMMDRINLMTENGGLFDKGYIEAELDIHPDLPFFSCHFIGDPVMPGCLGLDAMWQLVGFFLGWIGGKGKGRALGVGEVKFTGQILPNAKKVTYRIHMKRVINRKLVMGMADGEVEVDGRVIYTATDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STREM
Sequence: MSKQTLILLYGGRSAEREVSVLSAESVMRAIDYTKFFVKTYFISQTGQFIKTQEFSSQPAATERLMTNATIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESADIPQVAYTVYIEGQDLDRCLAETEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEVGLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAFKAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVRLAQEMFEKREGHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_PSEAB
Sequence: MPIITLPDGSQRSFDHPVSVAEVAQSIGAGLAKATLAGKVDGRLVDACDTIDRDATLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPTAKMVIGPVIEEGFYYDIFFERPFTPEDMAAIQQRMRELIDKDYDVIKKMTPRAEVIELFKSRGEDYKLRLIDDMPDEKAMGLYFHEEYVDMCRGPHVPNTRFLKAFQLTKISGAYWRGDSKNEQLQRIYGTAWADKKQLAAYIQRIEEAEKRDHRRIGKQLDLFHLQEEAPGMVFWHPNGWSVYQVLEQYMRKVQRDHGYVEVRTPQVVDRILWERSGHWSNYAENMFTTSSESRDYAVKPMNCPCHVQIFNQGLKSYRDLPLRLAEFGACHRNEPSGALHGIMRVRGFTQDDAHIFCTEEQVKKEAADFIKLTLQVYRDFGFTDIAMKLSTRPAKRVGSDELWDRAEGALADALNESGLAWEYQPGEGAFYGPKIEFTLKDCLGRNWQCGTLQYDPNLPERLDASYIAEDNNRKRPVMLHRAILGSFERFIGMLIEHYAGAFPAWLAPTQAVVMNITDKQADFAAEVVRILGESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVESKAVAVRTREGEDLGSMPVTQFAELLAQAVSRRGRQDSE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_SALNS
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LIPA_ECOLC
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PSEPW
Sequence: MTPIDAKRPLQLNDQGQLRHFLSLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVISLNVSTSSTSKGETLFDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVCPDVAVINGGDGRHAHPTQGMLDMLTIRRHKGSFENLSVAIVGDILHSRVARSDMLALKALGCPDIRVIGPKTLIPIGIEQYGVKVYTDLTEGLKDVDVVIMLRLQRERMAGGLLPSEGEFYRLFGLTTARLAGAKPDAIVMHPGPINRGVEIESAVADGKHSVILNQVTYGIAVRMAVLSMAMSGQNTQRQLDQENAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ASSY_CORU7
Sequence: MKDRVVLAYSGGLDTTVAISWIAKERNAEVIAVSIDLGQGGEDMETVRQRALGAGAVESIVVDARDEFANDYCLPTIKANGLYMKEYPLVSAISRPLIVKHMAEAAKEHNGTAVAHGCTGKGNDQVRFEVGFANTAPELEIIAPARDYAWTRDKAIAFAEENNIPIEQSKSSPFSIDQNVWGRAVETGYLEDLWNAPTKDVYAYTEDPALGQAPDEVIISFESGVPVAIDGRKVTVLEAIEELNRRAGAQGVGRLDMVEDRLVGIKSREIYEAPGAMTLIRAHEAMEAVTIERELARYKRGIDAEWSDLVYDGLWFSPLKRSLDAFIEESQEHVTGDIRLVLHAGNIIINGRRSDHSLYDFNLATYDEGDSFDQSLAKGFVELHGLSSKIAAKRDMGIL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPR_BACHK
Sequence: MKSGEKDYSVKEAMIFSQRIAQLSKALWKCVEKDWQMWIKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDDKRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIELIAILRNIYGQDFIDIFEKSLEDIEENFTESDQKLVKK
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: GPMI1_METBF
Sequence: MLHMTQAKKPLMLIILDGWGYREAREGNAILAARTPNLDHLIEEYPWCFLEASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQDLTRINFSIRKGDFFKNPAFLGAISNAKANDSSLHLMGLVSYGGVHSYMAHIHALIKLAQQEGVKKVYIHAFLDGRDVPPKAALKDIEELDAFCKENGNAKIATISGRYYAMDRDKRWDRTKLAYDALTMGVAPYKTPDAETAVSEAYKRGETDEFVKPTVITDSEGKPEAVIKDNDSIIFFNFRPDRARQLTWAFVNKDFENFPREKHPKVYYVCMAQYDETLDLPIAFPPEELENVLGEVLSKQGLAQLRIAETEKYAHVTFFLNGGQEKCYEGEDRCLIPSPKIATYDLKPEMSAYEVTEEVIGRIRSGKYDVIVLNFANMDMVGHTGIFEAAVKAVEAVDSCVGKIATVLKEVGGVAIITADHGNAEQMENPTTEEPHTAHTSNPVKCIYFGNDEVKGLKNGKLCDLAPTLLELLKIRKPEEMTGESLIIK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1, BPG-independent PGAM 1, Phosphoglyceromutase 1, iPGM 1.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: FER1_DESVM
Sequence: MGWTVTVDTDKCTGDGECVDVCPVEVYELQDGKAVPVNEEECLGCESCVEVCEAGAITVEEN
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.  This ferredoxin serves as a carrier for pyruvate dehydrogenase.
What are the official names of this protein?
Ferredoxin-1, Ferredoxin I, Fd I.
Protein: SPA24_MACFA
Sequence: MATPLGWSKAGSGSVCLAFDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQAHSHQHPREK
What is the function of this protein?
Binds DNA with high affinity but does not bind to TATA boxes.  Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter.  May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 24, Testis protein T6441 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPATA24 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Associated with chromatin.
Protein: Y248_METJA
Sequence: MRVFIIIIYFRCFSKDHKPYFVITMYESLKNYFFEEIKNDKLLKLPDDFYDDIREYIKNIKDDIELERVKYYFKELRKLRIYKALYLDNERENLLPEELNIIHAIENIVVELKIEETPEFKKPTEIDTPKPIYTINDIDVVKVDKNFPPFTDGTFIYDLNKNDVLSLDRKISHILEKHRIISRIGESYENPEES
What are the official names of this protein?
Uncharacterized protein MJ0248.
Protein: MOAB_STAAC
Sequence: MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
What is the function of this protein?
May be involved in the biosynthesis of molybdopterin.
What are the official names of this protein?
Molybdenum cofactor biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: SYK1_MYCPU
Sequence: MNDNIKLTEQEIIRREKLKKYESLGIKTFKKFDHEKINIYSNEIVEKYNHFSKDELLEKQIKLIIAGRILTQRGPFIVIQDTNGKIQLYVDKKELEEQKETLALLDIGDIIYVKGTLMKTMKGELTIKVNFFDLLTKGLTPLAEKYHGLVDVEERYRKRYLDLISNPNIKEIFWTRTKVISKIRKFFDEQNFMEVETPMLHSILGGANARPFKTYHNSLSSSFNLRIATELPLKKLLVGGIDRVYEIGRIFRNEGIDTTHNPEFTSIEFYQAYSNLEIMMEQTENLIKFIAKELGLSKIKNHDVEIDLLADFKKINMVDAVSEATKVDFRNIDLDKAIEVAGRYKVKVEKYFKVGHIINELFELLIEKTLIQPTFVTGHPIEISPLAATSEDERFTERAELFINTKEYANMFTELNDPLDQRRRFEAQLEEKESGNEEASEIDESFLSALEYGLPPAGGCGIGIDRLVMLLTEKESIREVILFPTLKKKQV
What are the official names of this protein?
Lysine--tRNA ligase 1, Lysyl-tRNA synthetase 1, LysRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_CORGL
Sequence: MAAIVIVGAQWGDEGKGKATDILGGLVDYVVKPNGGNNAGHTVVVGGEKYELKLLPAGVLSETATPILGNGVVINLEALFEEIDGLEARGADASRLRISANAHLVAPYHQVMDRVQERFLGKRAIGTTGRGIGPTYADKVSRVGIRVQDIFDESILRQKVESALDYKNQVLVKMYNRKAIVAEEIVQYFLSYADRLRPMVIDATLVLNEALDQGKHVLMEGGQATMLDVDHGTYPFVTSSNPTAGGASVGSGIGPTKITSSLGIIKAYTTRVGAGPFPTELFDKWGEYLQTVGGEVGVNTGRKRRCGWYDSVIARYASRVNGFTDYFLTKLDVLTGIGEIPICVAYDVDGVRHDEMPLTQSEFHHATPIFETMPAWDEDITDCKTFEDLPQKAQDYVRRLEELSGARFSYIGVGPGRDQTIVLHDVLADN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_XYLFA
Sequence: MKDNERRILLGRVVGGFGLRGEIKIESWTEPRDAIFRYQPWLLRSPTGTESMLNGARGYETGKRLIATFPGINDRNAVEAICGTEIYVPRSALPPPHPDEYYWVDLEGLQVHTLEGVVLGSVSHLFSNGANDVIVIHGERERLIPFVQPDYVKSVDFEAERIVVDWDPEF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_SHEFN
Sequence: MKRTFILMLDSFGVGAATDADKFGDVGSDTFGHIAQACADGKADIGRQGPLKLPNLARFGLGHAGFESTGKFAAGFADNVEVIGAYGHADELSSGKDTPSGHWEMAGVPVLYEWGYFSDLTNSFPKELTDKILERAGLDGFLGNCHASGTQILEELGEEHMKTGKPIFYTSADSVFQIACHEESFGVENLYNLCKIAREELEPYNIGRVIARPFVGTGPADFARTGNRHDYAVLPPAPTVLDKLKDAGGEVVSIGKISDIYAHSGITQQFKATGLEELFDETLAQIKRAGDNTIVFTNFVDFDSHYGHRRDTAGYAKALEYFDSRLPELLAILQPEDLVIFTADHGCDPTWVGTEHTRERVPVLAYGAGLSAGSLGRRKSFADIGQSIASYFKLEPMNYGESFIN
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ANAMF
Sequence: MRTIRHKAYKSLGQNFILDPSMAEKIVSYAGSIEGYNIIEVGPGFGTMTEIILRSKVASLLAIEKDRRLSPMHKGLMQKYPNYRYIEHDVLEINLETMISAPSKMIANLPYNISVILLLRMLKYIHNFEKLTLMFQKEVAERLVAKPGTKSYSILSVLVQLLCDVEKVKDLQPGAFSPPPKVCSSVVNITPLGNLRFPVDYSYMLKMLKKAFGCKRKTVRNALGLPHQEFDALLAECRIPPSVRAENLSVEQLCAVSNFLQSRQYQFSTG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_YERPY
Sequence: MASPLSPGSRILIGLIRGYQLVISPLLGPRCRFHPTCSHYGIEALRRFGMIKGSWLTLKRVLKCHPLNSGGDDPVPPKLDDNREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AMPA_NITWN
Sequence: MPDAVKVGFVPFSTASRGTLVVFCDETLKFGRAAGKALGSSAGLVKRAAAANQFKGKSATTLDILAPEGLKADRLIVVGVGKTPALKSSDFLKLGGVIAGKVRSDNNGVTIIAELPSATMEPDLSASLASGIRLRAYKFDRYKTRKKEGDDAVNRADVSIAVADVAAAKKAFAPVNHVVNGVIIARDLVNEPPNVLYPEEFARRASRLRAMGVGIDVLDVKAMTKLGMGALLGVGQGSARPSRTVVMRWNGGKKGEPPVAFVGKGVCFDTGGISIKPANGMEEMKGDMGGAACVVGLMHALAARKAKVNAIGAIGIVENMPDGSAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVARKFKPKVMIDLATLTGAIMVALGTEHAGLFSNNDELSERLTRAGLDTGERVWRMPLAPEYDKLIDSKFADMKNTGGRHGGSITAAQFLQRFVDDTPWAHLDIAGTAMGAPKSDINQSWGSGFGVRLLDRLVAEHYETKR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_CHLMU
Sequence: MNSTNNTDSQNLDPNASEVEKLLDESAEAEEKTDDHTPPSELFILPLNKRPFFPGMAAPLLIEAGPHYEVLTLLAKSSQKHIGLVLTKKEDANTLKIGFNQLHRVGVSARILRIMPIEGGSAQVLLSIEDRIRIVKPVQDKYLKAKVAYHKENKELTEELKAYSISIVSIIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEVLETTDMHDRIDKALVLLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKDDHAVDLEKFMERLNKRDVPQYAMDVIQDEMDKLQTLETSSAEYAVCRNYLDWLTIVPWGIQTKEYHDLKKAESILNKDHYGLEDIKQRILELISVGKLANGMKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKLVQALKQSAIMNPVIMIDEVDKIGSSYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDSIPDPLLDRMEVLRLSGYILEEKLQIATKYLVPRARKEMGLSAQNVSFQPEALKHMINNYAREAGVRTLNENIKKVLRKVALKIVQNQEKNPSKKSRFTITPKNLQDYLGKPIFSSDRFYEKTPVGVATGLAWTSLGGATLYIESVQVPSSSGKADMHLTGQAGDVMKESSQIAWTYLHSALERYAPGRPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPVLNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNVLIFPEDNRRDYDELPAYLKKGLKVHFVTHYDDVFKIAFPGV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_LEUMM
Sequence: MFDLIKAIIIGIIEGLTEFLPVSSTGHIILAEALMKIPSGNVWTKAFSSVFDYSIQLGAIFAVIQLYFDKLNPFSSKKTDHEKFQTWRLWIRVIVGVLPAIVFGFALNDFMDAHLMNFWVVSATLIIYGIAFIVIENRQKSIVPVITNVNQITFKLALYIGLFQVLSIVPGTSRSGATILGAIILGASRFVAAEFSFFLSIPVMFGVTFLKMGSFFRDGGSFTGMQSIVMLVGFIVSWIVAWFAIKFMMNYIKNNDFKVFGYYRIIIGAIFLVFGILGIVG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA_BUCAP
Sequence: MLILTRRVGETLIIGDEITVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKKQKKS
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2326_PECCP
Sequence: MNEPLKPRVTFDDASPQEPLPQLRAGLAFDEQSGTPFSPISREEEVPEEGAAEEAISAALRPKRSLWRRMVMAGIGLFGVSALAQGVQSLHNAWIQQDWIALGGITAGSLIVAAGVGSLVVEWRRLYRLRERAEERDVARDLLHSHGVGRGREFCEKLARQAGLDSGHPAIQRWQASLHETHNDREVLELYARLVQPVLDTQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIAALYGIELGYFSRIRLFRLVLINIAFAGASELVREIGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWLDDKPRLGDFRRELIGQVKETLQKGR
What are the official names of this protein?
UPF0283 membrane protein PC1_2326.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TOM7_YEAST
Sequence: MSFLPSFILSDESKERISKILTLTHNVAHYGWIPFVLYLGWAHTSNRPNFLNLLSPLPSV
What is the function of this protein?
Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  TOM7 is involved in assembly and stability of the TOM complex.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM7, Translocase of outer membrane 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Tom7 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: OXLA_ECHOC
Sequence: MNIFFMFSLLFLATLGSCADDKNPLEECFREADYEEFLEIAKNGLKKTSNPKDIVVVGAGMSGLSAAYVLAGAGHKVTVLEASQLVGGRVRTHRNAKEGWYANLGPMRIPEKHRIVREYIRKFGLELNEFVQETDNGWYFVKNIRKRVGEVKKDPGLLKYPVKPSEAGKSAGQLYQEALGKAVEELKRTNCSYMLNKYDTYSTKEYLIKEGNLSTGAVDMIGDLMNEDSGYYVSFVESMKHDDIFAYEKRFDEIVGGMDQLPTSMYRAIEKSVLFKARVTKIQQNAEKVRVTYQTAAKTLSDVTADYVIVCTTSRAARRINFKPPLPPKKAHALRSVHYRSATKIFLTCTKKFWEDDGIQGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDSNFFLSLTLNECADIVFSDLSSIHQLPKNDIQKFCNPSVIQKWSLDRYAMGAITTFTPYQFQDYSKALTAPAGRVYFAGEYTANAHGWIDSTIKSGLTAARDVNQASEL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme.  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino-acid oxidase, LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CMTR1_DROME
Sequence: MDEPSDDENSEPTPKKIKREWVKSYSNKAMEMMKKMGYENDKGLGKSNQGRLEPIIAVQQDGRRGFGLKLDTVQSSAGQWDPACEELEIPEPVLWLHNPGSRADAYSLDQLMGHLVTGEKKLTLDGETRYCDPAILHHILNAKTVFDDLNDNEKRRARSRCNPFETIRSSIFLNRAAVKMANIDSMCNFMFTNPRDPAGQTLVAPDELLYFTDMCAGPGGFSEYVLYRKSWEAKGFGFTLRGANDFKLEKFFAASPESFDTFYGVKEDGNIFDESNQDSLNEYIRMHTPQGVHFAMADGGFSVEGQKNIQEILSKQLYLCQFLTALKILRPNGSFVCKVFDLFTPFSVGLVYLMYKCFQQIAIIKPNSSRPANSERYLVCKYKRSDAETAGIVAYLNTVNLMLSDESQLDENDVLEIFNANELAEDEDFLRYIIDSNNAIGKKQIVGLRKIAAFAQNLELKETKQSEVRQECLKRWGLPDKLRQAPENKPTDRLLDELLADWANERSWLSLPATEMKGVASLNATIKNVADWYFVPVGREETNINACSLFLCKSRGNLLRYTEHKKWELVETAFEVQPRSIFFGQIVYEFYGEGRTIQRMAALHIIDGICLGGVDIRRRPYRERVSMCDKFARSLNKPYRKDRTFGALRSKPLFRLQDMGSFFANMRHYVLKDNSQRLGFALDDNKFFVPGGIMMFCELTNNYVSAHSRSRGQLYYFNVRNKESYYKDQIPRNKADEIFASFRFSFSCRLLWKWTDLRQVEELATEDNPKILFRSDFVKFIADKLGHS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs (PubMed:32504809).  Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1) (PubMed:32504809).  Positively regulates the Ago2-dependent small RNA pathway, with roles in both siRNA biogenesis and RISC assembly (PubMed:32504809).  Involved in facilitating conversion of pre-RISC into holo-RISC, possibly by promoting the unwinding of Ago2-bound siRNA duplexes and thus the retention of the guide strand in holo-RISC (PubMed:32504809).
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PQQA_BRADU
Sequence: MAWKAPKIVEVPCGMEINMYVSATRK
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity).
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.