PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_RHOCS
Sequence: MILGIGNDLVDVRRIERTIERFGDRFLDRVFTEAERRRAERRSAAGPHSPRAATYAKRFAAKEACAKALGTGLNKGVYWRDMGVVNLPGGRPTLALTGGALERLRQITPPGMVAEIHLTLTDELPIAQAIVLISAVPAPQP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_TRYB2
Sequence: MGVLGLSKLLYDRTPGAIKEQELKVYFGRRIAIDASMAVYQFVIAMKGFQEGQSVELTNEAGDVTSHLSGIFFRTLRMIDEGLRPIYVFDGKPPTLKASELESRRQRAEDAKHEFEKAKEEGDDEAMEKMSKRMVRVGRDQMEEVKTLLRLMGIPVVQAPSEAEAQCAELVKKNKAWAVGTEDMDALAFGSRVMLRHLTYGEAKKRPIAEYHLDEILEASGFSMQQFIDLCILLGCDYVPRISGIGPHKAWEGIKKYGSLEAFIESLDGTRYVVPEEFNYKDARNFFLEPEVTPGEEIDIQFREPDEEGLIKFLVDEKLFSKERVLKGIQRLRDALTKKTQGRLDQFFTITKPQKQVNSEASTAGTKRNRGAVALPGVLQRKSSSGHKKAVKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: FLGH_XANAC
Sequence: MSRLPSLSRPCLAIACSALLGGCVAAGDVRPFAEMAPIVPVVAPVAQPTAGAIYAAGPGLNLYGDRRARDVGDLLTVNLVESTTASSTANTSISKKDATTMAAPTLLGAPLTVGGLNVLENSTSGDRSFAGKGNTAQSNRMQGSVTVTVMQRLPNGNLVIQGQKNLRLTQGDELVQVQGIVRAADIAPDNTVPSSKVADARIAYGGRGAIAQSNAMGWLSRFFNSRLSPY
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PYRH_ANADF
Sequence: MPSDRAATPKPSYKRILLKLSGEALMGDGKYGISPKTLSAIAGDVKDCVDLGVEVALTIGGGNIFRGVSGATEGMDRSSADYMGMLATVINAMALQDALEKIGVNTRVQSAIEMHQVAEPYIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEIHADVLLKATKVDGVYTDDPKKNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIIVFDSTLRGNVRRVVLGEQIGTTVGRLEEK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_OLEA2
Sequence: MKNNTMNTLIGAAQDESPVDLLVRNVRLVNVLSGEIHDAHIAVKDGIVVGFEEYEALHVVEGNGRHCIPGLIDGHIHIESTLLSPARFAAAAAPHGTAAVMCDPHEIANVMGAEGIEYMLHASAGLPLSVYVMMPSCVPATHMETAGATLRAEDVQDFLSRYPDRMPGLAEMMNYPGVLFRDDEVMAKLEAAASHVIDGHAPLLRGKALNAYVLGGPASDHETSDADEAREKLRKGMHLMIREGGSQEHNLEELVTVLNEFNTQNVSFVSDDKVVNDLMESGHMDDILRKAMAAGIPPVRAVQMASINTARYFRLHRRGAVAPGYRADFVLLDDLQTMRISECYLGGRNVKEIDFTGHSAAFSANTVHVAGLNTDSLHVAAGNGNLRVIGIVPGQVITHALELPPTLREGAAVADPSRDLAKLAVFERHKGTGNVGLGFTAGLGLHKGALAGTVSHDSHNLIVAGMDDADMITAAEEVQCIGGGLAVACDGRVLASLPLPIAGLMSDAPVEDVLAGLRGVNEALATLGYKLSSPFAALAFLSLAVIPSLKLTDKGLVDVHKFEIVPLWTA
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RISB_NITMU
Sequence: MARYENILELEPNLNGEDLSIGIVMSRFNIEASEGLLGACVEELMKQGVDAGNVVLVSVPGALEIPLALQKMALTDQFDALIALGAVIRGETYHFEIVSEQSTNGVSTVQLDTGIPIANGILTTNTDDQALARMSQKGAEAARVAIEMANLQRTLDEMEQ
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RAD_HUMAN
Sequence: MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAAAGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
What is the function of this protein?
May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (By similarity).  May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents (By similarity).  Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity).  Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway (PubMed:18056528).  Inhibits phosphorylation and activation of CAMK2D (PubMed:18056528).
What are the official names of this protein?
GTP-binding protein RAD, RAD1, Ras associated with diabetes.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RGK family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: EFTU_MYCLB
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPNLNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLELVEMEVRELLAAQEFDEDAPVVRVSALKALEGDAKWVESVTQLMDAVDESIPAPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGIRQTTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVIKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTNISVTLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET23_MOUSE
Sequence: MDSVRPRAPWAPPPDPASLDSPTCEPGLMAGTQLFRFREEPVPGGNRAVLEVRVPQVLHVQYGMYVWPCAVVLAQYLWFHRRSLPGKAVLEVGAGVSLPGILAAKCGAKVILSDSSEFPHCLDICRQSCQMNNLPQVEVVGLTWGHISKDILSLPPQDIILGSDVFFEPEDFESILATVYFLMQKNPKVQFWSTYQVRSADWSLEGLLYKWDMKCVHIPLESFDADKEDIAESTLPGRHTVEMLIISFAKDSF
What is the function of this protein?
Histone methyltransferase that dimethylates histone H3 at 'Arg-17', forming asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling (PubMed:28930672).  Maternal factor involved in epigenetic chromatin reprogramming of the paternal genome in the zygote: mediates H3R17me2a, promoting histone H3. 3 incorporation in the male pronucleus, leading to TET3 recruitment and subsequent DNA demethylation (PubMed:28930672).
What are the official names of this protein?
Histone-arginine methyltransferase METTL23, Methyltransferase-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes in male and female zygote pronucleus and cytoplasm.
Protein: Y3028_ARATH
Sequence: MADVTFISSSIVRPQIINQEGREKIHLTPFDLNLLYVDYTQRGLLFPKPDPETHFISRLRTSLSSALDIYFPFAGRLNKVENHEDETVSFYINCDGSGAKFIHAVSDSVSVSDLLRPDGSVPDFFRIFYPMNGVKSIDGLSEPLLALQVTEMRDGVFIGFGYNHMVADGASIWNFFRTWSKICSNGQRENLQPLALKGLFVDGMDFPIHIPVSDTETSPPSRELSPTFKERVFHFTKRNISDLKAKVNGEIGLRDHKVSSLQAVSAHMWRSIIRHSGLNQEEKTRCFVAVDLRQRLNPPLDKECFGHVIYNSVVTTTVGELHDQGLGWAFLQINNMLRSLTNEDYRIYAENWVRNMKIQKSGLGSKMTRDSVIVSSSPRFEVYDNDFGWGKPIAVRAGPSNSISGKLVFFRGIEEGCIDVHAFLLPDVLVKLLADVEFLEKCG
What are the official names of this protein?
Uncharacterized acetyltransferase At3g50280.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: IDI2_STRP7
Sequence: MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLSTEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDSFSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRSWQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRRSGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTVLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMKKA
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX3_TRASR
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMILLMLGLTTNMLTMYQWWRDIIRESTFQGHHTPVVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGHRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSCB_BUCBP
Sequence: MNYFKLFNLPQKFELDVNNLTSQYYNLQKKFHPDSYQDKNIYTKKYLEKSMLLNQGYQTLKNMLTRAEHLLFLNNYKVDKKKKIVFNAKFLEMQIELFERLEIHKNKNNKHEINKILLEVSQIEKNYIKKLKNFCNLEKWKIAHSILYKLLFLTKFIKKTKKIQHEIIN
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: PAND_ALKEH
Sequence: MQLNMLKCKLHQACVTDTELDYEGSCAIDANLMDAAGIREFEQIHVYNLANGARFTTYAIRGEAGSRMISMNGAAAHLCSEGDRIIICCYANVDESELDRHEPALVYCDGDNRITHQRNGIPLQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_CUSEX
Sequence: MDIVSLAWAALMIVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: GATB_CHESB
Sequence: MTIIDTRTPDPKRLIPGATGDWEVIIGMEIHAQVTSRAKLFSGASTEFGAEPNANVSLVDAAMPGMLPVINEECVKQAIRTGLGLKAQINHRSVFDRKNYFYPDLPQGYQISQYKQPIVGEGIVIVSVGPAKDGSFEEIQVGIERLHLEQDAGKSLHDQHPTMSYVDLNRSGVALMEIVSKPDMRSADEAKAFLTKLRSILRYLGTCDGNMDEGSMRADVNVSVRRPGEPFGTRCEIKNVNSIRFVGQAIESEARRQIAILEDGGAIDQETRLFDPGKGETRSMRSKEEAHDYRYFPDPDLVPLVFDQAYVDALAAELPELPDEKKARFMASFGLSEYDASVLVAERATAAYFEKVAAGRDGKAAANWVINDLLGALNRTGKDIEDTPVSPDHLGTIIDLIKDGTISGKIAKDLFEIVWNEGGDPVRIVEERGLKQVTDTGAIEKAVDEVIAANPDKVEQAKAKPTLAGWFVGQVMKATGGKANPQAVNALVNQKLGIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: KATG_SALCH
Sequence: MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWEVNAVAARVLPVLEALQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDESNELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLQ
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: SIGB_MYCTU
Sequence: MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEHLLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKREMHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAMSAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIERDVMSKLRHGERADRLRSYAS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  A non-essential principal sigma factor that responds to cell envelope stress and hypoxia.  Controls a regulon of about 40 genes, with another 100 genes expression being altered during SDS stress and about 50 gene being altered during diamide (oxidative) stress.
What are the official names of this protein?
RNA polymerase sigma factor SigB.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: LDH_SALRD
Sequence: MIQRRTVGIVGTGNVGTAAAYAMFNQSLASEILLLDQDTRRAEGEAMDLMHGQQLVGGITCRAVEYAALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDVLTYICQELSSRPNRRILGTGTLLDTARFRALLGRHYGVDPRSVHAYILGEHGDSEVPIWSNATIGGQKIRGETVLGKEWEEEAMQSIFEQARDAAYEIIDRKGHTDTAIGLVIARIVRAVLEDQQNVLPVSTRPDGAYGIDDVCLSVPCVVGLEGMEKRVDPGLSDEEREALRDSARALRDSRADLTVGT
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF2_PSEPK
Sequence: MIRDILKMGDERLLRIAPPVPEHMLGSAELQQLIDDMFETMRHVGGVGLAAPQVGIDLQLVIFGFERSERYPDAEAVPQTILLNPVITPTSSEVEDGWEGCLSVPGLRGVVPRFKHICYQGIDPQGSPINRFADGFHARVVQHECDHLIGRLYPSRIQDFAKFGYTEVLFPGLEVSED
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: MIDNB_XENLA
Sequence: MEQQPSVPRSCTNVARETPMNLNIQSTTGTRYELSVPLNETVDGLKRRISQRLKVPKERLTLLHRETRLSSGKLQDLGISDGSRLTLLPSVEAGLMSQMSRPEQSVMQALESLTETQVNDFLSGRSPLTLALRVGDHMMFVQLQLAAQQSGGSHLQHRHVITRGADAGAPPQYRTLHTSTSALSHLASCTPGSTPPTTLSPTSSTHCDAPHSSPLTTSVFRSHGEGVSPCAEQVPCSTRGTEGTSSSPSSRSRKPGAIIESFVNHAPGVFSGTFSGTLHPHCQDGAGRPRRDIGTILQILNDLLSATRHYQGMPPSLTTLRCHTQCASQARNAKATSPQSTGPQQTTHPVGHCQAQTRTCKPSGDRLRQTENRATRCKVERLQLLMHQKRLRRKARRDSRAPYHWMPTRKSSRTSSNSSTSSGEGSLEIDFEDSLWKPDVKAELNSEFVVA
What is the function of this protein?
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4.  Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
What are the official names of this protein?
Midnolin-B, Midbrain nucleolar protein B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Nucleus, nucleolus. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm. However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus.
Protein: PURA_BRASO
Sequence: MANVVVVGAQWGDEGKGKIVDWLSEQADIVVRFQGGHNAGHTLVINGATYKLALLPSGVLRSGKLSVIGNGVVFDPQAFLDEVGKLQAQGLIISPDNLRVAENVTLILPLHRELDALRESSNTGTAIGTTRRGIGPAYEDKVGRRAIRLMDLADLDTLPHKIDRLLAHHNALRRGLGLELIDGAEILRELTAVAPKLLPYAETVWRLLDIKRREGKRLLFEGAQGALLDVDHGTYPYVTSSNTVAAQAATGAGLGPGAIGYVLGLCKAYTTRVGQGPFPTEQDNETGRKIGERGREFGTNTGRPRRCGWFDAVLVRQAVRTCGINGLALTKLDILDGFDTIEVCTGYRLDGKEIDHFPAGEGAQARVEPIYETIEGWKQPTANARSWADLPAQAIKYVRRIEELVGCPIALLSTSPEREDTILVQNPFEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_YERE8
Sequence: MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSVPTVWFSILLIYGVFALKSGPAGWEGFVGFLQNPLVLLINIITLLAAVLHTKTWFELAPKAANIIVKDEKMGPEPVIKALWVVTIVATAIILAVALL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEND_MYCTU
Sequence: MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGLAIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGYFGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIPLREPLVPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDTVVISGHGAGVHPNLAALPTVAEPTAPRSGDNPLHPLALPLLRPQQVIMLGRPTLHRPVSVLLADAEVPVFALTTGPRWPDVSGNSQATGTRAVTTGAPRPAWLDRCAAMNRHAIAAVREQLAAHPLTTGLHVAAAVSHALRPGDQLVLGASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEGAHERTGSPDSPPRTIALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQGDPRFSDVSSRIFGTPHDVDVGALCRAYHVESRQIEVDELGPTLDQPGAGMRVLEVKADRSSLRQLHAAIKAAL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: INA17_CANGA
Sequence: MIKTAKISTLRLAITRNARNLSFTTLVRSPEVDNSKIKTLEDLTRLETLEGVDPELIKRLINEKTQEFNTQDELKLLKSMQMEQDRLNEVPLKRFTRPLWIFILMASTFYLGAHLVWWKLAYEKKEVELKHKVDSLETTLKDVMKEKATGPTPCNNKKSWYKFW
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RGXA_ASPNC
Sequence: MRMPSAISIGVIAGLSVAASAVPSLQKNGTTCTVIPLGNGQDDVPNILSAVDECGQTSGGRVVLPAPYTYRINQRMTTHLTDSRLEIGGTLLFSDDIDYWVNNSYRVDFQNQSSAWRITGHDYVVDGGPRQGGVDGNGQLWYTWAKGGSNVFGRPMPVHVFESTRATLRNLAIRQPQFWAVLVDSSSHINLDNFYVNATNHDSSVSPEGEWVQNTDGIDTYRSDHITVTNWVYQGGDDAVAFKGNSTNIHVENVTVYGGPGIAFGSLGQYPDRTDIVENVTVRNVRVQPSFQRAMNSGVYFKSWIGVNYGVPPNGGGGGHGYVRNVSVENLRLKDVQLPVYIDTCLSYLFSENITQYCDTSTYEFEDLHFRNISGNGLATVTDYPGKNISFAVALLCSEKAPCTDLTFQDISITLPGNYTGKHVLCENAEAEGLPCNS
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Putative galacturan 1,4-alpha-galacturonidase A, Exopolygalacturonase A, Exorhamnogalacturonase A, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.