PharMolix/UniProtQA huggingface dataset:
Protein: DDL_RICRO
Sequence: MHKYQTHWVEHSIVKILSSTGKKHIALMAGGMSAEREVSLVSSEGVSKALIELGYRVTFIDMGADIAVRLQEIKPDIVFNCLHGTYGEDGGLPGLLNIMRIPYTHSGVLSSALAFDKIHSRIWFLTNNINMAESIVVNKSDNIKNDPMKRPYVIKPLTQGSSIGVEVIFAEDDFNFADYDFPYGDQVIIEQYIKGRELQVAVLNGKALGALEIKLLKNRFYDYETKYTAGFADHLCPAPLPANLYEKLLIESEKIYKTMNCKGPARAEFILEEQTNKLYALEINTHPGMMSLSIVPEIAAYAGINFTNLIEEIIKTASFES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_NITWN
Sequence: MVLPTTKDATAAGAGFDTVRIIGDIDALAEKHAGHEDVFRSAVSRLLKAELAKVRDAAQAKLLRDRHGRHCAEWLCFVQDEIIRLSFSAATRHLYHSPIPSDGERMAVVATGGYGRGLMAPESDIDLLFILPYKQTAWGEQVAEAILYCLWDMGLNVGHATRSVNESIRQARRDMTVRTGILEARFLTGDRALYDELISRFDTEVVQGTAAEFVAAKLAEREERHHRAGQSRYLVEPNVKDGKGGLRDLHTLFWIAKYVYRVRESHELLRRNVFDVREYRTFRRCADFLWSVRCNLHFATGRAEERLSFDLQREIAVRLGYTSHPGMQDVERFMKHYFLTAKDVGDLTAILCAKLEDQQAKPAPVLSRAMSKPPGAEVRRVPDSDDFIIDNNRINLAAPDLFKRDPVNLIRLFRLAQKNNLAFHPDALRMVRRSRRLINAQLREDPESNRLFIEILTSNDAETVLRRMNETGVLGEFIRAFGKIVSMMQFNMYHHYTVDEHLIRCIGILQDIERGDNDEVALAGELMRTINPEHRPVIYIATLLHDVAKGRPEDHSIAGARVARRLCPRLGFNAADTELVAWLIEQHLTMSKVAQSRDLSDRKTIENFAAVVQSVERMKLLTILTTADIRGVGPGVWNGWKAQLLRTLYYETEPVLTGGFSEVNRAQRMAAAEAEFRAAFTEWSGHELNAYIARHYPAYWLKVDLEHKIRHARFLRASEQSGRKLNINVGFDEARGVTELTILAADHPWLLSIIAGACASAGANIVDAQIYTTTDGQALDTIAISREYERDEDEGRRAARIAEIIEQVLEGRLRLPDVMPSRAAGKRLRPFVVEPKVTINNQWSDRHTMIEVSGLDRPGLLFQLTTAISKLNLNIASAHVATFGERARDVFYVTDLLGARITAPTRQAAIKRALVHLLASGNTAE
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: PRMA_DESAH
Sequence: MKWIHVNARFEADDMALAEELVAQIFFDLDLKGVVCEVPLPEPDEGFGSNALAQPDTHSISGYLPDLSTSDLLFADIKKKADALKGINVTLSTRIVDDQDWAESWKDFFFVTRITDTLVIRPSWREFEPKPGDVVIDLDPGMAFGTGTHETTAMCLALVQEQITPGASFLDVGTGSGILMIAAAKLGAGTLKGLDNDEAAVQIAGKNLEHNRISPQSFEIRCTTLDRYPHEKFDLVVANILAEVIISILPEIHSRLAPGGRAILSGIIIAWEERVKTALEDNGFTLVKTTTQGEWVALVAELV
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGF1A_XENTR
Sequence: MPQTPIFPSMLGSTCSGQVQPEMGEHCGDPVYQDGSLVSGSLEVLIERLVPTLDYYPDKTYIFTFLLSARIFIHPYEILAKVGQMCIKQKQQLESGSEADKAKLKSFAAKIIQLLREWTETFPFDFQDERARKEMKEIAQRITQCDEENGTIKKSISQMTQNVLVVLSTRGQFQEVREKIRQPVSDKGTILKTKPQSAQKDILSVCSDPLILAQQLTTIELERLGNIFPEDLMQIISHMDSLDNHKCRSDVTKTYNLEAYDNWFNCLSMLVATEICKVVKKKQRTRVMEFFIDVARECFNIGNFNSMMAIISGMNLSPVARLKKTWSKVKTAKFDVLEHHMDPSSNFCNYRTALQGATQRSQSANSSREKIVIPVFNLFIKDIFFLHKIHSNRLPNGHINFKKFWEISRQIHDFLTWKQVECPYEKDKKIQTYLLTTPIYTEEALFLASFENEGPDNHMEKDSWKTLRSTLLNRA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) with specificity for rap2a and other Ras family proteins (in vitro).  Plays a role in cell migration (By similarity).
What are the official names of this protein?
Ras-GEF domain-containing family member 1A.
Protein: NDUS6_PANTR
Sequence: MAAAMTFCRLLNRCGEAARSLPLGARCFGVRVSPTGEKVTHTGQVYDDKDYRRIRFVGRQKEVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHPKVYINLDKETKTGTCGYCGLQFRQHHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, Complex I-13kD-A, CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS6 subunit family.
Protein: GRLM_DICDI
Sequence: MIKLILSLIFLIICCNINPSESFKLITLTTGPTSDLGFNNMVNQGRIGVSKAMNIEDSRIFIVSGRNETYALLLPLIQNDDIDLVICSSQDHGDACKEIAAMYIDSPTIKTQFLVRGSGAATKNLIQITYNYASVNYISGMFAGLQTVKNKIGFLSPGSAANNNDSFVYAFWIGAKQVNPDVKFYYYNIGSYLDQDKTIAATQDLINIYGCDVIADTLDDFSAGNVAIQNNQYAMGTNGFPQRDVYGENVIFSYAYNWTKYFLPIAGSVANGTVPGKWYADFNKEDNYNFYDLSFGFKVSQNTKDLLIQKSRVLATTPRAGHPYYCNEYIEQYTKKYNLPTQAANSSCISTAGFFYINQPVGDMIYLGSYNIRLSKIEFSSSVQKGFSIVSGCLIAFVILMMVGIVYYKDTPSIRSASPIFLNFSLIGGIIIYIGIIIWVGPISTHQCNARFWLVTLGFSTLIGSLVVKNFRIWLIFDNPELKAIKITNYQLFPWVGLCLVINIVLMAILTSVGDLKAIEAQGIDSLGKYEYMTVCKMNSAGASTLYSILAYFAALLLVGVFVSWKIRIVDIEEFNESKAIANTLYAVSFCLFVIVPLMISPQEKQSETIILCVAGLFITTAALLIVFIPKFWRVFIYGKEGTNEMFKQKKSSSVATARAESLSKNSSNGGAHSGGGAVKTNRRGNIVSGDFTDDSESSLSEPNKPTKNNDGNVNVTAGAVLAEFTDDTISEFDENEVNEEPVKTESQE
What are the official names of this protein?
Metabotropic glutamate receptor-like protein M.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYFB_HELHP
Sequence: MIFSKHLLSHFVDISHLDIEQMCMRLSSMGLEVESAYPLKMPQKVVVGKILSLTPHPDADKLNVCKVSIGSQELQIVCGANNVKANQYVAVALEGAVIPHTKSGEIVIKQTNLRGIESCGMLCSSVELGLPKINDGIMVLDSTAGHLELGVELGNLPLFNDYVIEVGITPNRGDCLSVLGIARELATSYDLRLKHEVDMDNVVTLGLGRVLQILCDEKIEAHLLYRVVEVKQAYLPLDIALCLARNGSLVDDIMCNFLEYGTYMTGVILNAYKLYDCENKDIVLDNGLVAQLRIKKDENGLGAVFAHQKLSIIGVSYGERHFGTRSEIYIIEASYVNPTLIAKSLYKHAIKGDVQLTYRSTRGSNPNLEQGIDFLCRKMVLVSDALVYSGSHNIVQNIDEITIKTTFKAINQIIGIELDKEEIATILKRLNFKLDATCDENFFMVTVPNYRHDIQSIQDVAEEVLRIYGIDNVSSVPLLCSQSHNINNTYFTYKNTRKLAYGLIAYGFVECIHYVFASSQNLERLGFVRLDEDLELLNPITNELDTLRTSLLPAMLDSVKRNENLGFKNITLFEIGSVYSSKREEKSKLALVASGCMQDECYPHTKAVKWNLFAFGTICQRCVGDLSFRNIRDEANAKELLSHFCFTDERLLHPYQSAFVYQKDKPIGIIAKLHPQVATNMDLSEEIFICEIEIGMSDFSLPQAYEFSKYQKSTRDLTILIDKDIPFYRVRQILLEDQIAYVKNIYPIDVYYDKALGEKMALSIRIVLQSDEGTLQEMQLVQAVESVLSVLVREFDAVLRT
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGD_CITKO
Sequence: AVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAETFTEWNKGELNSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLITESVFARYISSLKEQRVAASKVLSGPKAQLAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPYFKKIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRT
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: ATPB1_PSEA6
Sequence: MSNVSTSVTAQYQLNPAQNTGLVAAVRGSIVDLIFEQHVPPIHNVLYAQNKHVVLEVVAQLSAQKIRTIALTATQGLARGMPVEDSGGPLKVPVGPSTLSRMFNVFGAPIDGHTYQHDGKWRSVHQAPPALTKISSQLQIFETGIKIVDVLCPLERGGKAGLFGGAGVGKTVLLSEMIHNMVSQQQGVSIFCGIGERCREGEELYREMKEAGVLDNMVMLFGQMNEPPGSRFRIGHAALTMAEYFRDDEKKDVLLLIDNIFRFIQAGSEVSGLMGQMPSRMGYQPTLGTELAGLEERIANTEDGAVTSIQAVYVPADDFTDPAAVHTFSHLSATLVLSRKRASEGFYPAVDPLQSSSKLATPTVVGQRHYDVARQVKQILAQYNELKDIIAMLGLEQLSKKDRDVVSRARRLERFFTQPFFTTEQFTSMKGKFVSLEQALTGCERILQGEFDDYPESALYMIGEIDEAIKPKQSATEKNSSMNSDLKPSNSESNSPGPKNSEPDNAIPSSAKPNVSQPNTFKQDAQNESLEEPQNGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL17_BACC3
Sequence: MAYRKLGRTSAQRKAMLRDLATDLIINERIQTTETRAKELRSVVEKMITLGKRGDLHARRQAAAFIRNEVANAETGQDALQKLFADVAPRYAERQGGYTRIAKIGPRRGDAAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y4835_BACC1
Sequence: MKMTSKKMKDELMKRLSRPEWDFQYDSEKEVLRIEQKDSKKGINVSLPGVVAKWEVNKEKAIEEVAYYVQEALIAMHKEENNAAKILPVIRSTSFPKQAEEGNPFIMTDHTAETRIYYALDSNKTYRLIDERLLQKLGLTEQQVREMALFNARSLGYEFKQDTVAGNTFYFLNTNDGYDATRILNESLLQSMREKISGDMVVAVPHQDVLIIADIVNEIGYDIIAQMTMKFFAEGHVPITSLSFVYEDGDFEPIFILAKNRKKTDGKEKG
What are the official names of this protein?
UPF0354 protein BCE_4835.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: LONB_ARCFU
Sequence: MNEEVREILGGLDFESTKDVAVPERLIDQVIGQDHAVEAIKKAAVQKRHVMLIGSPGTGKSMLAKAMAELLPKEELEDILVYPNPQDPNQPKIRLVPAGKGREIVEAYKEEAMKKAQARNFLIFTLVFLVIGYTVLTNPGNLIWGIIAAVLILMMSRYFIPREDRNVPKLLVDNSDKVTAPFEDATGAHAGALFGDVRHDPFQSGGLETPAHERVEAGAIHRAHKGVLYIDEINTLTIESQQKLLTALQDKKFPITGQSERSSGAMVRTEPVPCDFILVAAGNLDALMGMHPALRSRIEGYGYEVYMNDTMPDTPENRQKLVRFVAQEVVKDGKIPHFDKYAVAEIIKEARRRAGRRNHLTLRLRELGGLVRTAGDIAKSEGSDIVRLEHVLKAKKIAKTIEEQLADKYIERRKDYKLFITEGYEVGRVNGLAVIGESAGIVLPIIAEVTPSMSKSEGRVIATGRLQEIAREAVMNVSAIIKKYTGRDISNMDVHIQFVGTYEGVEGDSASISIATAVISAIEGIPVDQSVAMTGSLSVKGEVLPVGGVTQKIEAAIQAGLKKVIIPKDNIDDVLLDAEHEGKIEVIPVSRINEVLEHVLEDGKKKNRLMSKFKELELAAV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Degrades polypeptides processively (By similarity).
What are the official names of this protein?
Archaeal Lon protease, ATP-dependent protease La homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family. Archaeal LonB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_CLOBA
Sequence: MRKAIIAGNWKMNKTVDEAVKVVEELKPLVKDATCDVVVCPTFVCLDAVKKATAGSNIKVAAQNMHFEESGAFTGEVSPGMLEAMGIEYVVLGHSERREYFNETDEAINKKVKAAFAHNITPIVCCGETLEQRESGVTNNFIACQIKVDIAGLTKEQAEKVVIAYEPIWAIGTGKTATKEQANETILAIRNVVVEMYGKEVADKVRIQYGGSVKPNTITEQMAMSDIDGALVGGASLKAEDFSGIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BURA4
Sequence: MDHIRNFSIIAHIDHGKSTLADRIIQVCGGLADREMEAQVLDSMDIERERGITIKAQTAALSYRARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPAANPENAIEEIEDVIGIDATDATRCSAKTGLGVEDVLESLIAKVPPPKGDPAAPLQALIIDSWFDNYVGVVMLVRIVNGTLRPKEKIKMMATGAQYPVEHVGVFTPKSRNLESLSAGQVGFIIAGIKELTAAKVGDTVTHVAKAASEPLPGFKEVKPQVFAGLYPVEANQYDALRESLEKLKLNDASLQYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVVYEVVQSDGSTIMVENPAKMPEPGRIAEVREPIVTVNLYMPQDYVGSVITLCEQKRGSQINMQYHGRQVQLTYEIPMAEIVLDFFDRLKSVSRGYASMDYEFKEYRSSDVVKVDMLINGDKVDALSIIVHRSQSQYRGREVAAKMREIIPRQMYDVAIQAAIGAHIVARENIKALRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKQVGSVEIPQEAFLAILRVEDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RAF1_THEVB
Sequence: MSQDQDALTTEVLQRLRRKEGTWQDWGAGCRQLQKQGLSPQAIFEATGIEPIHQNQLITALQVSQSLGEAPESVRAYFQTRGSDLLYELRVLSAGDRLAAATLIVEKQLDVTAVHEVCRALKAVSYRKDNSEGFGESVGDRIGRYYWQLARQQRDLAQRSRLIAQGLRFVESASGRQALEKLLTDFTVVPAVNQPRLPLYRLDTAEEVPYLVPVAGTAPLTATVLQQVPRLSCTEVFRVVAVPQGMSLVALPAWQVLLNAVDPVAILWPAADLPAELPPSPEGLPIAQVLLVVDRGLAEWDRDRYLLIAPSPSEAVQLAWLPEPPTATVVGQLLLVLRPPQVLDESLNRELWFFEE
What is the function of this protein?
Required for optimal reconstitution of RuBisCO upon expression of rbcL-rbcS subunits in E. coli.  Only interacts with the large subunit (cbbL, rbcL).  Probably acts in the final stages of RuBisCO assembly, possibly participating in the addition of the small subunit (ccbS, rbcS).
What are the official names of this protein?
RuBisCO accumulation factor 1.
What is the protein family that this protein belongs to?
Belongs to the RAF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Interacts with the large subunit of RuBisCO in the cytoplasm.
Protein: DPO3_CALS4
Sequence: MVPATFLENMQIKKVRVEKKSRKLTVVVSSFSSNAQKLSEFQSFLEESFPSLKEIKIVVESPSLSTVEEVLENWEKVVLELSEEYPSSLSFLKTCDVAKEGQNRITVKAPTYAIYEMAKSSKLDFAIREFLRNRYELNLDVELIFSEEGEEIAEKIIEEDIKAIEEVIQKDEKSKKEKSRSEENRVLLGKEMKAKPISIKDVSAETDEVVIEGEIFSIDFKELKSKVLMVFDITDYTSSILVKTFLTEEKYEILKDEIDVGTFVRLRGNVIYDKYEGDLVIDLKDLELIPPKKRMDLSEEKRVELHLHTQMSTLDAVPSATEVIKRAAEWGHKAVAITDHAVVQAFPEAMEASREYGVKVIYGMEGYMVDDGIPIVTGESEASLEGEFVVFDIETTGLSNINDEIIEIGAVKIKNKKIVDTFETFVNPQIPISSFITKLTGIDESMVKDAPLIEEVLPKFLEFAKGAVLVAHNANFDVSFIKSKAKKLGLTVENTVLDTLELSRHLYQDLKNYKLDTLAEFFEVKLLHHHRAVEDAKATAEIFIKMLEKLQEIGIKSVSEINSVLMEREVDVKKLPVYHVTILVKDQKGLRNLYEIISRSNLEFFHRTPRIPKSLLVKMREGLIIGSACEQGEVFRALVSNLEEKKLEDIINFYDYLEIQPVGNNEFLIERGEVRSVEELKEINRKIYELGKKYNKLVVATGDVHFLDPWDDVYRKILMAGKGYKDADRQPPLYFRTTEEMLMEFEYLGEEAAREVVIENPNKIAEIVEDVKPIPEGTFPPVIEGAEEELRRITLEKAHEIYGDPLPPIVQERLDRELNAIINNGYAVMYVIAQKLVSKSLQDGYLVGSRGSVGSSLVATMSGITEVNPLPPHYVCPKCKHSEFVTDGSFGCGVDMPDKYCPNCGTLMKKDGFDIPFEVFMGFEGDKEPDIDLNFSGEYQPIAHRYTEELFGKGHVFRAGTIGTLADKTAYGYVKKYFEERNLTVHKSEIKRLTMGCTGIKRTTGQHPGGVMVVPKDKSIYDFTPIQRPADAEDTDVITTHFDYHSLSGKLLKLDILGHDDPTVIRMLEDLTGVNARKIPLDDKKTMSLFTSVEALGIDPEELGTPVGTLGLPEFGTKFVRQMLIETRPTTFDELVRISGLSHGTDVWLNNAQDIIREGIATLKEVIAARDDIMLYLISKGMDKKLSFKIMENVRKGKGVTQEEIEEMKKHGVPDWFIQSCQKIKYMFPKAHAVAYVIMAFRIAYFKVYYPEAFYATYFTVRADDFNLDIVLGGKESIKRAIKEIEAKGNNATPKEKNLLTVLEVALEMYLRGIKFTNVDLYRSDAEKFLITEEGLLPPLNSLEGVGIQAAKAIAQERENGKFISIEDFRNRTRVSKTVIEILKQYGCLEDLPESNQLSLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_MANSM
Sequence: MTTKCPHFQTQQCQSCQWINRPYDEQLNEKQIHLKQQIAPLDQSQLRWSAPFQSRQSGFRNKAKMVVSGAVERPVLGILKDQNAPQSAVDLTDCLLYSAGFKPIFPVLKDFIGRAGLVPYNVAKQKGELKYILLTESGYQGDIMLRFVLRSENKIPLIRRELAKLREKLPQLKVISANIQPQHAAILEGEKEIFFTERQVLEERFNRIPLFIRPQGFFQTNPQVAEGLYGTAQQWVKDLPVNKLWDLFCGVGGFGLHCAKALQEKNPDIELTGIEIAPSAIYCAGLSAQKCGLKKVNFQSLDAANFALNQDENKPDLVIVNPPRRGIGKPLAQFLNQMQPQFILYSSCNAISMTKDLLELTHYQLQKIQLFDMFPHTSHYEVLTLLIKR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: RL3_CANGA
Sequence: MSHRKYEAPRHGHLGFLPRKRAASVRGRVKSFPKDDKSKPVALTSFLGYKAGMTTIVRDLDRPGSKFHKREIVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYSAKYAQNGAEIERELARIKKYATVVRVLVHTQVRKTPLVQKKAHLAEIQLNGGSISEKVDWAREHFEKTVSVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHHRTSINHKIYRIGKGDDEGNAATNFDRTKKTINPMGGFVHYGMVNNDFVMVKGSIPGCKKRVVTLRKSLYTNTSRKAVEEVTLKWIDTASKFGKGRFQTPAEKHAFMGTLKKDL
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOZK_BACSU
Sequence: MTDYSQFPRENILCVDMKSFYASVSAVAMGLNPLTCYLAVVGNTDRQGSVVLAASPALKKDFGIKTGSRLFEIPEDPRIYIVNPQMKLFIRVSTEITKLFYRFVPEKCVHTYSID
What are the official names of this protein?
DNA repair protein homolog YozK.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
Protein: LEVR_BACSU
Sequence: MRRIDKIYHQLKHNFHDSTLDHLLKIQGNSAKEIAEQLKMERSNVSFELNNLVRSKKVIKIKTFPVRYIPVEIAEKLFNKKWDTEMMEVKDLQAFSGNSKQNHQHISTNPLELMIGAKGSLKKAISQAKAAVFYPPNGLHMLLLGPTGSGKSLFANRIYQFAIYSDILKAGAPFITFNCADYYNNPQLLLSQLFGHKKGSFTGAAEDKAGLVEQANGGILFMDEIHRLPPEGQEMLFYFIDSGSYNRLGESEHKRTSNVLFICATTENPSSALLKTFLRRIPMTIHIPSLEERSLNERVDLTTFLLGKEAERIKKNLSVHIDVYNALIHSAKFGNVGQLKSNVQLVCAHGFLHNLDRNEVIELTVRDLPDEIKQEWMSSSKNMQRSKAISEYVNITTIISPIVEDETTKIDEDLSFNLYHLIEEKVKTLMKEGLSKKDINQYILTDVHLHVRSFFHHQAFQKDNLLTFVEDDVIQMTKQLKEIAEHELDCTFDRKFIYFLSMHIDAFLKRGKQIDVLNTQETDEIRDTHVKEYRVAMIFKDKIQEYFKVAIPEIEVIYLTMLIHSIKSLKENKRVGIIVAAHGNSTASSMVEVATELLGSTPIAAVDMPLTVSPSDILECVAEKMKQVDEGEGVLMLVDMGSLAMLESRLEEKTGISIKTISNVTTSMVLDAVRKVNYLNLNLHAIYQSVTKDFIELWERQPAASGKKKALVSICTTGSGTAKKLEDILTTIVNKASDTPIHILTVSSIKLANSIKEIEKEYEILATVGTKDPKINAPHVSLEVLIEGEGEKLIQQAITKGSISLSNGLNEANIIVRELCEDSLKKYLVFLNPHHVIDMLLEWLQTVQDELGVIFNNAVLIKVIMHTAFAFERVIKQNPIAFSEEEEINDQLKEMVYVTERTLAPYEEKLGLRISDDEKLFIAAIFAEEVHGQLF
What is the function of this protein?
Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system, and sacA for levanase.
What are the official names of this protein?
Transcriptional regulatory protein LevR.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family.
Protein: FABH_BART1
Sequence: MIRSIIRGVGSALPKRSLSNDELAKFVETSDAWIVQRTGIHQRYIANENETTVSLGVKAAQAALINAGLTIKDIDCIILATSTPNRTFPASAVEIQYALGMNHGFAFDIQAVCSGFIFALTTGDSYLRCGAAKRILVIGSDTFSRILDWEDRTTCVLFGDGAGAAVLEAEEIEGGIAFQRGILSAKLRSDGAYIDKLYVDGGPSTTQTTGYLRMEGREVFKYAVGMITDVVDDCFAAAGMDSSQLDWFVPHQANKRIIEASAKKLKISSDKVVITVDKHGNTSAASVPLALTTALCDGRIKRGDLIMLEAMGGGFTWGAILIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_HAEI8
Sequence: MSKISLDALNVRNALIEKGIETPMIDPTQAKDERRESIAKHMHEVMKLIGLDLRDDSLEETPNRLAKMFIDEIFSGMDYANFPKMTKIKNQMKVSEMVQVNDITLTSTCEHHFVTIDGKVCVAYYPKDWVIGLSKINRIVSFFAQRPQVQERLTEQLLTAFQTILETDDVAVYVKATHFCVKARGIRDTNSYTVTSAYGGVFLEDRDTRKEFLATVQK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PTC1_PHYBI
Sequence: MAFLKKSLFLVLFLALVPLSICEEKKSEEENEEKQEDDQSEEKRGLVTSLIKGAGKLLGGLFGSVTGGQS
What is the function of this protein?
The native peptide is a cationic amphipathic alpha-helical antimicrobial peptide with potent activity against both Gram-positive and Gram-negative bacteria (PubMed:12709067, PubMed:15222751).  It has weak activity against fungi and shows low hemolytic activity (PubMed:12709067, PubMed:15222751).  Acts in a synergistic effect in combination with Phylloseptin-B1 or Dermaseptin-B2 at doses that are not active alone (PubMed:12709067, PubMed:15222751).  In membrane-mimetic environment, it adopts well-defined helices that lie parallel to the micelle surface (Probable).  A short amidated analog (AA 45-67), shows potent activity against Gram-positive, Gram-negative bacteria, and fungi (Probable) (PubMed:15222751, PubMed:17128968).  In synergy with Phylloseptin-B1, this analog acts more potently (PubMed:15222751).  Its rapid rate for killing E. coli suggests that the membrane is its primary target (PubMed:15222751).  This analog is cytotoxic toward differentiated eukaryotic cells (nucleus fragmentation and apoptotic bodies are observed in Hela cells) (PubMed:17128968).  This analog has a moderate hemolytic activity (PubMed:17128968).  It may interact with anionic phospholipids (DMPG) by decreasing the associated water content of the phospholipid heads (CO), replacing water molecules by peptides themselves (Probable).  This analog may have a strong capacity to cross membranes (Probable).
What are the official names of this protein?
Plasticin-B1, PTC-B1, Dermaseptin PBN2, DRP-PBN2, PBN2 KF.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Plasticin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: FOLD_IDILO
Sequence: MPAQIIDGKTIAATVRQAVKQQVKERIDSGLRAPGLAVVLVGSDAASEVYVGNKRRACEDVGFRSFDYDLPITTTQKELEKLIEELNDDDAVDGILVQLPLPAGLDATPILERIRPDKDVDGFHPFNIGRLSQRIPALRPCTPKGIMTLLEHTHVDLHGLNAVVVGASNIVGRPMSLELLLAGATTTVCHRFTKDLSDHVKRADIVVVAVGKAEFIPGEWIKPGAIVIDVGMNRLPDGRLTGDVEFSVAAERAGWITPVPGGVGPMTVASLIENTLQACVDYHDVR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CF118_HUMAN
Sequence: MAEEREPELYLKWKHCETPGVKTLCNLKHCETPGVKTLCNLKKLLNRLQKDHREDVYLYISGHLNPNKLYQPPETILQHWPNAHRPKGERASEVGEPPAGKVARMKEALAHFTIHTALVPSEAQDTPLFRYLNPQASLSHTSEEDFLPVEAVREGKEEKKGGPPGRGPPGWRRREELRLPDLKVLCYQEAGSRGTRDRHHYVSSYLAGATSADRYRMFLRFQKEVLAKQDLLKNDFTGSKAAAGHERKLQQELQKICTCSPQQFNRLHVFGKVFEDICNSSLIFGDLLKKVKDEYELYMATLLESQPAAQYEALLAQLKALGQRPVKTADMDLAREELRMLVTATKAALEQNDRLRSELEMEVALLQSAKERSESSEKHIIDENRLTLTEKVEKKRCEILSKWDEIQALEKEIKTTLVHTGISDITENRIKSIEHEAIQLETENMILKKKIKGPLEIYQGICKIRGNRR
What are the official names of this protein?
Uncharacterized protein C6orf118.