PharMolix/UniProtQA huggingface dataset:
Protein: RL9_STAAR
Sequence: MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNLKQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEALKAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: FLZ14_ARATH
Sequence: MLTKRTHPMIGKISELLVGVNRSTAAPFFDVLMTSPKSPLDFKILPQISQRNSSKRFYDDNLGGSVGLGIVAALENSNTRRITSVCRSEPNQPGRSDPVQFMSHGGSTDGEDEEMFIMDEEDYTLVTCHHGPSGSCNTRVYDKDGFECFSSKINDDRRERLFVVDVVTESPENSPEFQGLGFLNSCYLCRKKLHGQDIFIYRGEKAFCSTECRSSHIANDERKERCRSKFSTSPYTAGQIFSTGVLVT
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
What are the official names of this protein?
FCS-Like Zinc finger 14.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FLGH_BRUAB
Sequence: MNKAILAVAMVLLLAGCATKPEEIGRAPDLSPVAAHLGMQNNPQFNGYPARPGKASYSLWDQRSTNFFKDPRAATPGDVLTVIISINDRANLDNKTDRERVSKGIYGGGGSFATSSITGAAAGGDMDASVNTHSDSKSKGKGTIERSEDIRLQIAAIVTDTLPNGNLIIRGSQEVRVNNELRVLNVAGVVRPRDISGNNTISYDKIAEARISYGGRGRLSEIQQPPYGQQILDQFSPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RNPH_NITEU
Sequence: MPRCNNRAPAQMRPVRIIRHYVRHAEGSVLIEYGETRVICTASVIEKVPPFLKGAGQGWLTAEYGMLPRSTGERMQREAAKGKQSGRTMEIQRLIGRALRSILDLEKLGERTIQMDCDVIQADGGTRTASITGAFVALYDAIDYLRAERMISQNPIRDHVAAVSVGILKGQPLLDLDYLEDSGCDTDLNVVMTGSLGLVEVQGTAEKVVFSRQELDVMLNMAQQGLQELFDVQRKALETVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SURE_METFK
Sequence: MRILLSNDDGYFAPGLNILAQHLAKVADIVVVAPERDRSGASNSLTLDRPLSVHRANNGFYYVNGTPTDCVHLAVTGLLDELPDMVISGINDGANMGDDTIYSGTVAAATEGFLLGVPSFAVSMSRHGVQHFETAAKFMVSLVKRYQKDRFPPPVLLNINVPDVPFDQIKGTEVTRLGKRHKAEPVIKSTTPRGQTVYWIGAAGSAQDAGDGTDFHAVSQNRISITPLQIDLTQYSQREQVKNWLAL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R45_PANPA
Sequence: MITFLPIIFSILVVVTFVIGNFANGFIALVNSTEWVKRQKISFADQIVTALAVSRVGLLWVLLLNWYSTVLNPAFYSVELRTTAYNIWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACHLFVVNMNQIVWTKEYEGNMTWKIKLRRAMYLSDTTVTMLANLVPFTVTLISFLLLVCSLCEHLKKMQLHGKGSQDPSTKVHIKALQTVISFLLLCAIYFVSVIISVWSFKNLENKPVFMFCQAIGFSCSSAHPFILIWGNKKLKQPFLSVLWQMRYWVKGEKPSSS
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 45, T2R45.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL18E_METB6
Sequence: MTRTVEKTNPRLTNLILLLKNTSRENEAKIWREIAGRLETPNRNYAEVNLSKINRYAQKGETIIVPGKVLGSGVLDQSVRIAALNFSESATSKIRDAKGQCMTIEQLLKDNPKGSGVRILR
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: HEMA_I78A9
Sequence: QDLPGTDNSTATLCLGHHAVPNGTIVKTITDDQIEVTNATELVQSSSTGKICNNPHKILDGIDCTLIDALLGDPHCDVFQDETWDLFVERSNAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPANGFFSRLNWLTKSGSTYPVLNVTMPNNDNSDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTKRSQQTMIPNAGSRPWVRGLSSRISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDLINGKVNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RS14Z_ELUMP
Sequence: MATKAWVAKMAKPQKFAVRYHNRCQVCGRPRGYYRDFGLCRICLRKMAHQGLIPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: HIS6_IDILO
Sequence: MLAKRVIPCLDVRDGQVVKGVKFRNHEIIGDILPLAKRYAESGADELVFYDITASADGRTVDKSWVERVAREINIPFTVAGGIRSVEHAQTMLSMGADKISINSPALLNPNLINTLVEEFGQQCIVIGIDSFYNEQSGEYEVHQFTGDESKSHKSAWQTKDWLQEVISRGAGEIVLNCMNQDGVRQGYDIAQLSALRGHCSVPLIASGGAGEIQHFVDAFQKAQVDGALAASVFHKNLFSISEVKAAMAANNIAVRPIEALQETT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEG7_HCMVM
Sequence: MQLAQRLCELLMCRRKAAPVADYVLLQPSEDVELRELQAFLDENFKQLEITPADLRTFSRDTDVVNHLLKLLPLYRQCQSKCAFLKGYLSEGCLPHTRPAAEVECKKSQRILEALDILILKLVVGEFAMSEADSLEMLLDKFSTDQASLVEVQRVMGLVDMDCEKSAYMLEAGAAATVAPPTPPAVVQGESGVREDGETVAAVSAFACSSVSDSLIPEETGVTRPMMSLAHINTVSCPTVMRFDQRLLEEGDEEDEVTVMSPSPEPVQQQPPVEPVQQQPQGRGSHRRRYKESAPQETLPTNHEREILDLMRHSPDVPREAVMSPTMVTIPPPQIPFVGSARELRGVKKKKPTAAALLSSA
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: RL17_PETMO
Sequence: MRHRVKTKKLNRYASHRKALLNNLARSVFESESIITTTAKAKAVRPLVERIITKAKEANSTDLPERRVALNRDINKHFNDRKLVYKIVHEIAPRYENRNGGYTRILKIGYRKGDASELSILQLLPKEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL34_THEM4
Sequence: MKRTYQPSRIKRKRTHGFLARKKTTGGRRVLKNRRRKGRWRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NQRE_NITEU
Sequence: MNSLAGLFITAVFVENLALTFFLGMCTFLAISKKIEVAFGMGIAVIVVQTLTVPINNLVYQYLLRDGALVWAGLAEIDLTFLGLVSYLGVIAAIVQILEMFLDRFMPALHSALGIYLPLIAVNCAILGGSLFMVERDYNFTESLVYGLGSGFGWALAIVALAGVRERLKYSDVPDGLQGLGITFISAGLMAMGFMAFSGIRL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALR_SYNY3
Sequence: MIRQRAWVEIDQAALVHNVRQFRQYVGPKTNLMAVVKADAYGHGAVRVAQTALQAGADWLAIATLGEGIELREAGITAPILLLGGINSPEEIEAIAHWRLQPTLCSPEQAQLFNDILLKLGKVLPVHLKLDTGMTRLGTPWPQAANFVGLVQSLPQLRLASLYSHLATADDPNTATMLQQQERFAKAIASLRQARLPIPKLHLANSAATLHGQAWHYDMVRVGLGLYGLYPAPHLGDCLDLKPVLTVRAKITQIRTIPPGTGVSYGHQFVSEETMPMAVVGIGYADGVPRNLSNQLEVLLRGQPVRQIGAITMDQMMVDLRGIDDPQVGEVVTLIGQDGDRQITADHWASTLGTISWEILCGFKHRLPRILI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RL6_BRUME
Sequence: MSRIGKKPVPVPAGVTASVEGQTVKAKGAKGELSFVVHDEVLVKMEDGAVRVDPRDQSREARSKWGMSRTMISNIFVGVKDGFEKKLEISGVGYRAAMQGKNLQLSLGFSHEVVYDVPAGITVAVPKPTEIVVTGIDKQQVGQVAAEIREYRGPEPYKGKGVKYAGEKIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: KTI12_DANRE
Sequence: MPLILMCGYPCSGKTRRAQELRDYFTQNTGRKVHIVGDEDQGIDKNSVYADSQKEKNLRGALRAEVERKVNKDDIVILDSLNYIKGYRYELFCLIKHTQTPHCLVYSLTSADLSSEWNKDREADSQYTQEILDALILRFEAPDSRNRWDSPLFTIQQDDSLPFEAICDALFKRKAPPPNQSTKSQPLSSTNFLYELDKVTQDVLMAVLESQKTSVPGDLISIPGATEKIELTRSLNMVELRKLRRQFISYTKMHPTENIGQIANMFVQYLNKSMH
What are the official names of this protein?
Protein KTI12 homolog.
What is the protein family that this protein belongs to?
Belongs to the KTI12 family.
Protein: Y4178_BORBR
Sequence: MAAAVVQLADLPFIRQFGFSPLVVGIVCGMLYGNFLRGTMPADWGAGVHFTARRLLRIAVAFYGLNISIQQIAAVGLPGLAVSVGVVASTLLIGTVAGQRLLGLDRDTAMLTAAGSAICGAAAVLAFEPTLRAAPHKSAVAVATVVLFGTLSMFLYPVIYHAGWLPFDTQALGIYIGGTVHEVAQVVGAASNIDPATTEVATIVKMTRVALLVPVLLVLGFWLRASAAAGADGKSHAKLPVPWFAIGFLVLAIVNSLDILPSDLVTAIRKLDVFVLTMAMTALGIETRFAQIRKAGPRVMALGLVLYAWLVFGGYGIVKLAT
What are the official names of this protein?
UPF0324 membrane protein BB4178.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_PSEPK
Sequence: MKAFTQHTGIVAPLDRANVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDVGQPYQDNSKRPLNEEFVLNHARYQGASVLLARENFGCGSSREHAPWALDEYGFRSIIAPSFADIFFNNSFKNGLLPIILSDEEVDELFKQVEANPGYQLTIDLQAQAVTRPDGKVLHFEIDAFRKHCLLNGLDDIGLTLQDSDAIKAFEAKHRASQPWLFRDA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PGPLC_DROME
Sequence: MPFSNETEMSQCSNAKRRVNDPLTGPKNCSTSSTDSGVILNDNVAAFRPEKETKDRGTGEGQFQSKSEEKTESKRISVEHTVNITTENVGKTSSPAVSIRSTTISVVSIDDNAIDSSSIDSDSEAEAEDYTVQKLGHQVTYPPNSSHLRDLNQGLTVISRHVAPGEAAVPPPNPLEAGIVAKQILNGNLAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDKWKPGEGPAGGQDNPAFNGGPSTNGSAPGSKHEDPAQTPPICPFLPNTVGRKAVTVTVVFVTLTFLLGIVLATTTNLFGKTLNQSKIRDDDDYRQNIPINSTIDLDNIGGGLILRFVERQQWLAQPPQKEIPDLELPVGLVIALPTNSENCSTQAICVLRVRLLQTYDIESSQKCDIAYNFLIGGDGNVYVGRGWNKMGAHMNNINYDSQSLSFAYIGSFKTIQPSAKQLSVTRLLLERGVKLGKIAPSYRFTASSKLMPSVTDFKADALYASFANWTHWS
What is the function of this protein?
Mediates the response to LPS, peptidoglycan and Gram-negative bacteria.
What are the official names of this protein?
Peptidoglycan-recognition protein LC, Immune response deficient 7 protein.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: EX7L_CHESB
Sequence: MEEAKKDDSLSNVAEYSVSEISHALKRTIEDTFGHVRVRGEISGFRGAHSSGHCYFSLKDERARMEAVIWKTTFARLRFPPQEGLEVIATGRLTTFPGSSKYQIVIESLEPAGAGALMALLEERKRKLAAEGLFAESRKRPLPFMPHVIGVVTSPTGAVIRDIIHRITDRFPVHVVVWPVRVQGETTGAEVAAAISGFNALQPGGTIPRPDILIVARGGGSLEDLWGFNDEAVVRAAAASAIPLISAVGHETDWTLIDLAADRRAPTPTGAAEVAVPVKAELEANIARLSARLKGAISRCLDRRRQETRSLARALPSPDQLFALPRRRFDEAAGRLGRALQTSTQGKRLHLNAVRVSIATLDRRIAQARRDANQCGERLPLVYQGLVRHRRARFDRDAARVSPRVTLQRITTLGERLKIAIARKDRAVSLRVERARTVYEQAVRLAESLSYKSVLERGFALVRDGEDRPLKRASDVKPGETLRLQFADGNIGAISTGKSSNTNRKSAPAREPGKQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFD_HALMA
Sequence: MVTFLAGGTGTPKLLAGADDVFSPAATTVVANTGDDIELGGHLVCPDLDTVLFLDGEVLDRETWWGIADDTAETHTELTRLADAAGLDGGPRYLPDDAQTAGRDIARWRRFSGVAEFMHIGDRDRAVHVTRTSLLDEGRSLTAVTRTLADAFGLERTLLPMSDDPVASIIHTPSGPMHFQEWWVGRNGEPPVEDVEFRGAERASATDAVLTALDDTVVIGPSNPVTSLGPMLAIDDIQRALHETTVVAVSPFIEDTVFSGPAADLMAGVGLEPSTAGVAEAYPFADSFVLDEEDSTPLDVPVVRTDTTLNDAADAERVNRAVETALSEVA
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: AROA_SULIK
Sequence: MIVRIYPSEISGTIKAPQSKSLAIRLIFLSLFTRIHLHNLVLSEDVIDAINSVRALGVEVKNNSEFIPPEKLEIKKKFIKLKGSGTTLRMLIPIVAAIGGEVTIDAEESLRRRPLKRIVEALSNYGISFSSSSLPLTITGKLSSYNIKISGDESSQYISGLIYALHILNGGSIEILPPISSKSYILLTVDLFNRFGSNVKFYGNKIHINPNNLVEFQGEVAGDYGLASFYALSALLSGGRTTIVNLWEPKEYFGDHSIVKILKEMGATSEYLDGKWYVEAKDKYSSIKVNIDDAPDLAMTIAGLAAIAEGTSEITGIERLRIKESDRIESIRKVLGLYGVGSEVKSNSILIFGINKRMLSSPITDCLNDHRVAMMSSALALVNGGVITSAECVSKSNPNYWQDLLSLNAKISIE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_LEGPA
Sequence: MQNEYSQFEQRKRDHIELALMPANQSNELNPFDHFSLVHEALPDLDFKDISIQSIRFKKPVEKPFIISSMTAGHSNALEINSRLMEACSKTKWAMGVGSQRRELSDKQAAFEWAPLRRDFPMVSLFSNLGIAQLIDTPISAIQRLIDTLQAEALIIHCNPLQECIQPEGTTNFQGCWTALEALVKKIASPVIIKETGCGFSKNTLLRLNNIGVAAVDVSGVGGTHWGRIEGHRANKDPIRHRTADTFRNWGIDTLQSTRNAISLNPSFEVWGSGGVRNGLDAAKLFALGATTVGFAKPMLEAALDSTGQVLTQMNIIEYELKTAMFCTGSRVLDDLKEKACP
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_THEMA
Sequence: MYLQDVIMKLNDFWASKGCLLEQPYDMEVGAGTFHPATFFGSLRKGPWKVAYVQPSRRPTDGRYGENPNRLQRYFQYQVIIKPSPENSQELYLESLEYLGINLKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQIGGISLKDIPLEITYGLERIAMYLQGVDNVYEVQWNENVKYGDVFLENEREFSVFNFEEANVGLLFRHFDEYEKEFYRLVEKNLYLPAYDYILKCSHTFNLLDARGAISVSQRQTYVKRIQAMARKAARVFLEVQANENSPA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_SALTY
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRQAAELGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDSTYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRMCPDAQGALPGSVISVSPLRVACADGALEIITGQAGDDITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSVDIAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: RS21_ACET2
Sequence: MSEVRVKENESLDSALKRFKRQCAKAGVLAEVRKREHYESPSVRRKKKSEAARKRRYK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SMN_HUMAN
Sequence: MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (PubMed:9845364, PubMed:18984161).  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (PubMed:18984161).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (PubMed:18984161).  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate (PubMed:18984161).  Within the SMN complex, SMN1 acts as a structural backbone and together with GEMIN2 it gathers the Sm complex subunits (PubMed:21816274, PubMed:22101937, PubMed:17178713).  Binding of snRNA inside 5Sm ultimately triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (PubMed:31799625).  Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development (PubMed:23063131).  Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination (PubMed:26700805).  May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
What are the official names of this protein?
Survival motor neuron protein, Component of gems 1, Gemin-1.
What is the protein family that this protein belongs to?
Belongs to the SMN family.
Protein: UN05_PINPS
Sequence: IIYDXVGQCDKDFYRPELPR
What are the official names of this protein?
Unknown protein from 2D-PAGE of needles, N147.
Protein: DCA16_HUMAN
Sequence: MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL
What is the function of this protein?
Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins.
What are the official names of this protein?
DDB1- and CUL4-associated factor 16.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNOY_CRAGI
Sequence: KDWNYFTFAQQWPIAVCAEHKSCFIPDSVVGWGIHGLWPSSDTESKGPENCNGSWPFDINNVMPLVPELKKYWPNLYPDTKANSFWEHEWSKHGTCATSLPATSNELKYFGMGLKLHAKYNISRILVNQGILPSKTAGYMINETEAAVKRELGVDAVIECVYDKEKTKKQLLYEISICLTKEFELISCNKKEVSETTCPRKEPFFYPPVHDNN
What is the function of this protein?
Releases mononucleotides from RNA in the order of 3'-GMP, 3'-AMP and 3'-UMP.
What are the official names of this protein?
Ribonuclease Oy, RNase Oy.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Secreted.