PharMolix/UniProtQA huggingface dataset:
Protein: VPS15_DICDI
Sequence: MGNTVGAPIVSEYLEDEIGPIVFKKSLGNARFLKTVKAYHSEEGYVVVKIYKKRNTKESLEKYKIMLKEIKDNFNITPSFNIMPYQHFIETDRSGYLIRQYFHNNLYDRLSTRPFLSMIEKKFIAFQLLKALEQSSFKGVFHGDIKSENVLVTTSNWVYLSDFACYKPTFIPEDNPADFSFYFDTSGRRTCYIAPERFYETNRGAPSNNELTPKMDIFSLGCVIAELFLDGFPIFDFSQLLSYRKGEYSPEPIIRQRIQDPNIQTLILHMIQKDPDQRYTPEKYISKWNTVFPQYFSFAHQFIPELMRLENDDRVMCISDKFDEIVDIFKNNSITNLFKSNLNQSTNSNTIGSFRVSTPSSPILISNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQTTTTTTNTNINTTQQQQQQQQQQQQQLQRPLSKLDDIGKNIANIIYKTEQFVKESDEFDKTDITNIKELNIQTTPTINTSTINRVIQTSKTNTNLDTINENSNNNIGVNRKKVTVVEGLDLFLSVIYTAVKHCQFPSTKVKCVGSLLVRLAEMLDDECRLQKIVPYIMSMISPEQPTLVRVEALRSLAKVLEMVQTFPPSESSIFGQYILPSLSQLSHESTDEIIRIAFAEILPQLATTAKRFLEIAQHYRDPDSEGIMESRKDRAKFRVYDSDLQEVQDQFFNKVSDLLTKDSCNTLKKIILSDIYRLCVFFGRQKTNESVLPLIITFLNDRDWQLRCAFFENIVAVCTVVGAGSLESFIYPCILLALTDEEEFVTEKALSSLSELCSLGLLRKPILLELLVKTSPMLLHPNNWIRYGVVSLIVKICQSLSKADVYCYVKPKLSPFLVNLNGNGNGNAEISDTITESNLIQLLDSPISRESFNKIVKFIARNRINLSSSINSILANDNDNFNGESFNSNGSGGGGNPNLVSSTGGSNRRLRALSNKFFVPNILSASNSSINSTSGDIGSLLSQSTEESLAFLRQMTSIGISDSDQNKIIKCFDYLQSKKCKDLESANNSEGNVIVIRTNGTTIISSSNNSNNNTLSSSTTSSNSTTPTNSTVNLHSVLNNTTIIQQQQQQLQQTITQQSITQQQQQQQQQQQVSGGITTGGTTTTTLGRSSSPQLTGLNPSILSNSNNIQLSSSVVDVTKLPNSIPIRMVKIRGGDQSLNNSTVSLGSVAGGNIITPSTSLSNSNTMVGNNNNNSYNTSTSSSPLSSSVLNSSVGMNNLTNSNANSINNSSGINNNNSNNNSVNSNNYNNMNNNTMNNSVNLMNSNQIGQQQQQNPNTVKIDLVSPSDLNVVSKKYYIRDPKMGLSTILKVETNVECSIKVPLPLPDLGSTDSVLGGGLLSSGGVGGGVGGTGGGNINGVSGINGNVGGGGGGVGVGTVGSGGNGSIGGGNSGINNGSGGGGVNSGGNSGINSGSTNSSGSLYGNGNGLDNLPNSTWRPMGILVSHFFEHKAAVNEIQVSSDNLFFATASNDGTVKIWDCQRMEKSVTNRARQTYAQQEGRITSISICEKTHSIASASDKGSIHVFRVGISGKQKNGNIKYTNLSTVKNITETTRGNIVSVSHYSTNSSSVVTYATTKGGIHGWDLRSQQDAFNLVNDASLGLIQAFLIDPNRNWLVTGTSRGFLTCWDLRFGIPLYSVRVSNGRILKFAPYMLAKSASESWVYISTEQDNVIVFDLSNKKTTRVFKRSYEQPPQQQPQQPQPPQQQQQQQSQMNRSINMTSSTTTTTTSSYDFGTENLKTSSYSQLPSNPLVNSIVNNSNINNNNNNNDNSNNVTIFKPTPLVRALLNPPNCPFLITAGDDKRIKLWDWNNLPQSYYVSIGKEPPPFYTHKFSNDTSNAYEIHEEVWHDTSSSSFYSNSAMFGGGGGGQPMSTSLSSSSLSQQQHQAQLQLQYQLQQQQQQQQYINHLQQQKSKTSISMPTVHHQEPILDIKMMEVPNPMLISASTDGVVKVWK
What are the official names of this protein?
Probable serine/threonine-protein kinase vps15, Phosphoinositide 3-kinase regulatory subunit 4, Vacuolar protein sorting protein 15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RBFA_TROWT
Sequence: MDRVKEFAMKDQIRAHRMAGRIRHLISRQIETKLRDQLGLVTITEVQVTGDLHHAKVFVTVYGTKDEAQTALKILEDNRANFRRSLGVLKVRFVPTVEFELDRLFEDAGIMDELIQRARESDKRIAAGASGPIDNDATALMDKVVDQEARNPDSWHTAPTSSSHTAGLCLVRASSPIACNIDSTTLCKPRTPGPGL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_DICNV
Sequence: MTKSELIERLVMKYPQLRAQDVEDTVKLMIERICHTLEKGDRVEIRGFGSFSLHYRESRQGRNPKTGESVRVPAKSIPYFRAGKELRERVDEEINQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SYP_STRA1
Sequence: MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMRQEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDQSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHKDYEDLDVTYEDYRKAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAVTPNRTDLNRWLVLDKTIPSIDDIPEDVLEEIKAELSAWLVSGEDTIAYSTESSYAANLEMATNEYKPSTKAATFEEVTKVETPNCKSIDEVAGFLSIDKNQTIKTLLFIADEQPVVALLVGNDQVNDVKLKNYLAADFLEPASEEQAKEIFGAGFGSLGPVNLPESVKIIADRKVQDLANAVSGANQDGYHFTGVNPERDFTAEYVDIREVKEGEISPDGKGTLKFSRGIEIGHIFKLGTRYSDSMGANILDENGRSNPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGAYRFAWGINFPEELAPFDVHLITVNVKDQESQDLTEKIEADLMLKGYEVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKASEGIVEVKIKASGDTIEVHADNLIETLEILTKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_STAHJ
Sequence: MNNLLSMEHLSNEDIYELIQTACDYKSGKQTLPQFEGKFVSNLFFENSTRTKCSFEVAEQKLGLKEVNFETSTSSVQKGESLYDTCKTLESIGVDLLVIRHSQNAYYEELENLNIPIANAGDGSGQHPTQSLLDIMTIYEEYGSFEGLNILICGDIKNSRVARSNFISLISLGANVMFSSPDEWVDDSLDAPYVQIDDVIDQVDIVMLLRVQHERHGITGEANFEANDYHEQYGLTMDRYNKLKDKAIVMHPAPVNRGVEIDSELVEAPKARIFKQMTNGMYLRMSVINKLLSGKEA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ARND_PSEU2
Sequence: MQAGLRIDVDTYRGTREGVPRLLDILDEAQVKATFFFSVGPDNMGRHLWRLVRPTFFWKMLRSNAASLYGWDILLAGTAWPGKPIGRDLGPLMRRALDAGHEIGLHAWDHHGWQANAGHWSDRQLTAQIHRGVDCLSDILGHPVVCSAAAGWRADQRVVQAKEAFGFRYNSDCRGASLFRPLLADGSLGTAQIPVDLPTFDEVIGPHLKPDAFNDYILGRFAARQLNVYTLHAEVEGIIMADGFRQLLKRANTQGIHFAPLGHLLPDAIERLPSGHIVRGHLPGREGWLGVQQ
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: GCH1_NOSP7
Sequence: MTIASSNGSNYSQSPLIPDLADAITPRPDRNTNNGRQADVFPPKEEHIEEMKDAVRKIILGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELVNDAIFDEGHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIPNQKVVGLSKLARIVEMYSRRLQVQERLTRQIAEAIQTILEPRGVAVVMEASHMCMVMRGVQKPGSWTVTSAMVGVFQEEHKTREEFFNLIRHQPAFF
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GCST_LEPBJ
Sequence: MSQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGEPKIVLDFLELVTCNSVASLSDFQVQYNAILNENGGLVDDVTIYKFSVEKYMICSNASNYETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIFSKFLGRELDSIKYYHFALLDYQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSELGKPQGLLPCGLGARDTLRIEAKYPLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPRENFRVLDFQGNEIGKTTSGTFSPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITTKPFIPGSIRKN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: KU70_COCIM
Sequence: MAESEYNREDDSFEEEEEVDDSGYKSVKDAVLFAIEVSESMLTAAPNPTSKKARPESPATAALKCAYHLMQQRIISNPKDMIGVLLYGTESSKFYDDDEDGRGSLPYPHCYLFTDLDVPAASDVKELHALVEDEDRAAEILVPSKEPVSMANVLFCANQIFTTKAPNFSSRRLFIVTDNDNPHSKDKVLKSAATVRAKDLYDLGVVIELFPISTPDHDFDTSKFYDDMIYRASPTDPEAPNYSCTSTKTSGADGISILNSLLSSINSKSVPRRALFSNLPLELGPEFRISVSGFLIFKRQAPARSCYVWLGGEQPQIVKGVTTLVADDSAREVEKWEIRKAYKFGGEHVAFTQEEQSALRNFGDPVIRIIGFKPMSSLPIWASTKHSTFIYPSEAGFVGSTRVFSALQQTLLKQKKFALVWFVARKNAAPVMAALIPGEEKLDDNDAQVIPPGMWIQPLPFADDIRQNPETHNIVAPEPLIDKMREIIQVLQLPKGRYDPQRYPNPSLQWHYRILQALALDEDLPDQAEDKTIPKYKQIDKRAGEHVLEWGEELETQNRLLENSKPITSTLAKRPAPSRKAEGDERATKRVRAESTGDAEVKMHYEKGSLNKLTVTILKDFLLSHNLSGTGKKADLIDRVEEFFDRK
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit Ku70.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: YHEU_SALEP
Sequence: MIIPWQGLAPDTLDNLIESFVLREGTDYGEHERSLEQKVADVKLQLQSGEAVLVWSELHETVNIMPKKQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: TM158_MOUSE
Sequence: MLPLLAALLAAACQLPPAHGGATDAPGLAGTPPNASANASFTNEHSTPRLLASAASAPPERSGPEEAPAAPCNISVQRQMLSSLLVRWGRPRGLQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRLRAPAGAPTALPAYPAAEPGPLWLQGEPRHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTAGAPAAAPAAVPAGTTAAAAAAAAAAAAAAAAVTSGVAPK
What is the function of this protein?
Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide.
What are the official names of this protein?
Transmembrane protein 158, 40 kDa BINP-binding protein, p40BBP, Ras-induced senescence protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM158 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NRDR_ACET2
Sequence: MKCPYCGYIEDRVIDSRPTDEGSAIRRRRECSKCLKRFTTYEKVESLPIMVIKKDKSRQAFDREKLLNGILRACEKRPVSIEQLEKLVDDIESQIHNSLQREVTSKDIGEMVMAKLKNLDEVAYVRFASVYRQFKDINTFMDELRKLLNEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SYGA_VIBCH
Sequence: MQKYDIKTFQGMILALQDYWAQQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPIATAYVQPSRRPTDGRYGENPNRLQHYYQFQVIIKPSPDNIQELYLGSLRVLGVDPCVHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGIERLAMYIQGVDSVYDLVWTDGPLGKVTYGDIFHQNEVEQSTYNFEHADVDFLFTYFDQCEKECKYLLELEKPLPLPAYERILKAAHAFNLLDARKAISVTERQRYILRIRNLTKSVAEAYYASREALGFPMCKKSEQK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MYCLB
Sequence: MRPALFDYRHLASGKVREIYRIDDEHLLMVASDRISAFDYVLDSTIPDKGRILTAMSVFFFSFVDAPNHLAGPPDDPRIPEEVLGRALVVRQLDMLPMECVARGYLTGSGLLDYQATGKVCGIPLPPGLVEASRFAAPLFTPAMKAVLGEHDENISFSRMIEMVGVVRANQLRDRTLQIYLQAADHALKTGIIIADTKFEFGIDRDGNLLLADEIFTPDSSRYWSVDDYRVGVVQRSFDKQFVRNWLVSPESGWVRAGALSPPSLPDDIIEATRLCYVEVYERISGMSFDDWIGPGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CHSTA_HUMAN
Sequence: MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDVYSAKQEFLFLTTMPEVRKLPEEKHIPEELKPTGKELPDSQLVQPLVYMERLELIRNVCRDDALKNLSHTPVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSDAEIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRRNRTETRGIQFEDFVRYLGDPNHRWLDLQFGDHIIHWVTYVELCAPCEIMYSVIGHHETLEDDAPYILKEAGIDHLVSYPTIPPGITVYNRTKVEHYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN
What is the function of this protein?
Catalyzes the transfer of sulfate from 3'-phosphoadenylyl sulfate (PAPS) to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides.  Participates in biosynthesis of HNK-1 carbohydrate structure 3-O-sulfo-beta-D-GlcA-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-R, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult.  May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis (PubMed:9478973).  Sulfates terminal glucuronyl residue of the laminin globular (LG)-domain binding epitope on DAG1/alpha-dystroglycan and prevents further polymerization by LARGE1 glycosyltransferase.  Likely defines the chain length of LG epitope, confering binding specificity to extracellular matrix components (PubMed:32149355).  Plays a role in down-regulating the steroid hormones.  Sulfates glucuronidated estrogens and androgens with an impact in hormone cycle and fertility.  Has a preference for glucuronyl moiety at the 3-hydroxyl group of a sterol ring rather than the 17-hydroxyl group, showing high catalytic efficiency for 17beta-estradiol 3-O-(beta-D-glucuronate) and dehydroepiandrosterone 3-O-(beta-D-glucuronate) hormones (PubMed:23269668).
What are the official names of this protein?
Carbohydrate sulfotransferase 10, HNK-1 sulfotransferase, HNK-1ST, HNK1ST, HuHNK-1ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: GSA2_BACMK
Sequence: MKKFDKSIAAFEEAQNLMPGGVNSPVRAFKSVGMNPLFMERGKGSKVYDIDGNEYIDYVLSWGPLIHGHANDRVVEALKAVAEKGTSFGAPTEIENKLAQLVIERVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVAYNDLESVKYAFEQFGDDIACIIVEPVAGNMGVVPPQPGFLEGLREVTEQNGALLIFDEVMTGFRVAYNCGQGYYGVTPDLTCLGKVIGGGLPVGAYGGKAEIMRQVAPSGPIYQAGTLSGNPLAMTAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHNIPHHINRAGSMIGIFFTDEQVINYDAAKSSNLEFFAAYYREMVEQGVFLPPSQFEGLFLSTAHSDADIEATIAAAEIAMSKLKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_NICBI
Sequence: MTRSLKKNPFVANHLLKKIDKLNTKAEKEIIVTWSRASTIIPTXIGHTIAIHNGKEHLPIYITBSMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TI_VERHE
Sequence: NTDPEQCKVMCYAQRHSSPELLRRCLDNCEKEHD
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor, VhTI.
What are the subcellular locations of this protein?
Secreted.
Protein: GATZ_ECOBW
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQREQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIAIVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: RS8_YERE8
Sequence: MSMQDPIADMLTRIRNGQSANKVAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDAKPVLELALKYFQGKAVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DLGD_ECOBW
Sequence: MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRE_ECO57
Sequence: MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHPGLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
What is the function of this protein?
Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides.
What are the official names of this protein?
NAD(P)H-flavin reductase, FMN reductase, Ferrisiderophore reductase C, NAD(P)H:flavin oxidoreductase, Riboflavin reductase [NAD(P)H].
What is the protein family that this protein belongs to?
Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
Protein: DXO_XENLA
Sequence: MEGNKSMQREKIDRPMKRGPEQNSLSPPLAKCPFMSCSSLKTLHSLYQGSFPFYRLPSEVGHFSLDENRQYHQDNRKLRYYSPPVGIREKGSPGWNVMDGYESHYVRRNEDEKEGLLHILTWLEKNRGVLGAHVEGGSKRPIDRDFVTWRGHLTKILCTPYETQEGWLLAVTLFKGTFYISEQETEAAQKKRKERSLEQERLMYSGYKFESYICADSPDRQPSQSAVVNTNEGFCSVLLARLTSHSLLISGEVDCTDPSAKKSIPPTCYIELKSSAQIRNPHQQRSFNRYKLLKWWCQSFLLGIPIIVAGFRSPEGRIVSLETFKTSDIPHLVRGERNSWDPAVCMNFCNKFLSHIKSVVTRDDPRLVYLFAWEPGCDVTFTVHTDPEYTILPSWYVNSVN
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay.  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation.  Specifically degrades pre-mRNAs with a defective 5'-end m7G cap and is part of a pre-mRNA capping quality control.  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1).  Also has 5'-3' exoribonuclease activities: The 5'-end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs.  Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5'-end triphosphate to release pyrophosphates.  Exhibits decapping activity towards FAD-capped RNAs (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Decapping and exoribonuclease protein, DXO, 5'-3' exoribonuclease DXO, Dom-3 homolog Z, NAD-capped RNA hydrolase DXO, DeNADding enzyme DXO.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YK068_YEAST
Sequence: MQANHSVSYLYESSTSKRSNGLFSQTQKQGSFQKALSQTQEEIEDEDLMVDLNTGSLTPVKLKYWTQMSAMTEKFGKL
What are the official names of this protein?
Uncharacterized protein YKL068W-A.
Protein: IML2_PICGU
Sequence: MFKGLRKKASALSLTPTSSSASLGGSNHPQYSKILKQVRDFEIALRAMDFLLDDRAEEGMKLLETESKKHSEMHSDQPAGIFPLAMGVMDFIEATLGFEPEVMARAHETLSNAEAASLTNSKYNTKHQLNTSMIYPPGTEFQVTLAESTLLNALVMLLTENNSFLEAAKALLKLRKAYQTLDSLYKRIKESEPVFNRNLAKLKRGTSSKNVSTVDLPGFESTDNLGSSNASSSSLPEDVKLMNSLEQIFQMRKSRVEGTNLGRDVNPDRVNLFKDASSDHIPRMSSLRDLQANPSPRAVSPNVALQNSVFSNKPIGTDYDSDEDDDEFTDALETLQEDIPISAPMPIYMKSNGGNRIASGTESIISFSTDYSASTSSDLNSNHLHVSTIDEFIHSGVQLCFGILQVVLSLIPPTIGKVLSIVGFKGDFEAGMKMLWRTAITSRNIHGELALLCLLVFYDGPIEFIDNGYQVPNKDSKIAREVFAIDNRSTVSDEELKAITENPSSYTPQLLERARTHFKHNALWILQQGRMLAAQGQLDEAISLMQGFTDDPDNKINMRQIEGLFLFDRSMLYAFRHSFDECARDFVKLVDKNSWSQGLYLFFAGCSYLEKYRMIKLGLLQVENEQETLKELAEKAEHFMKLGPTYVPGHGVNAANKKGGIGGNKKQLPFDKYLLRKMAHLEEVQKQNPKLAFIDCVGTSPYHEIIYFWNGYNRMPTKDLELSIKLLGYSGAPDSEFSANTSSNNYSYIKETMDEAMLRYFFQAMALRSLGRHSEGLALLDSHVISKYVTQDSPLANFKFTKMTYSPFLYPTALYEKSRFVWNLRTSAPDFDVRKSITDCETLLKKAEIVSDIGDYEMSSRTSMNIKASLDRVTKLRNQYL
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: PYRI_BACFR
Sequence: MSENKQALQVAALKNGTVIDHIPSEKLFTVVSLLGLEHMTTNITIGFNLDSKKLGKKGIIKIADKFFCDEEINRISVVAPHVKLNIIRDYEVVEKKEVRMPDELKAIVKCANPKCITNNEPMATLFHVIDKDNCVIKCHYCEKEQKREDITII
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: KDSB_ACIF5
Sequence: MSFCVLIPARLASTRLPRKVLLDVGGIPMIEQVRRRALESGAAQVVVAADHPEVVDCIRSYGGEALLTAAEHVCGTERLAEAARLLGLADDAIIVNLQGDEPGMTPALLHATAQLLLDHPQRQMATAAVPITHWDELADPHAVKLVLDAEGCARYFSRAPIPWDRSHFPLSSGQTLPQTPGIWWRHLGLYAYRNAFLQDYAAWSASPLEVIESLEQMRALERGVQIAVYCAAEAPAAGVDTAADLDRVRDLFP
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.