PharMolix/UniProtQA huggingface dataset:
Protein: CXE11_ARATH
Sequence: MPSVGVKLYSVFFKFLLKHRLQNRIQSSGDESSSDPFGVTTRPEESVAAPNPLFTDGVATKDIHIDPLTSLSVRIFLPESALTPLEPSTSACVYSGKARTLNNIAGSDLLSRRNSLGSSNSLLSHKVESRRNSYGYTTGSSSPEAGSSDVYRGYAPSSSGGNSRKLPVMLQFHGGGWVSGSNDSVANDFFCRRMAKHCDIIVLAVGYRLAPENRYPAACEDGFKVLKWLGKQANLAECNKSMGNSRRPGGEVKKSEVNKHIVDAFGASLVEPWLANHADPSRCVLLGVSCGANIADYVARKAIEVGQNLDPVKVVAQVLMYPFFIGSVPTQSEIKQANSYFYDKPMCILAWKLFLPEEEFSLDHQAANPLVPGRSPPLKFMPPTLTIVAEHDWMRDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDMLLRTPQAQACAEDIAIWAKKYISLRGHEFSY
What is the function of this protein?
Carboxylesterase acting on esters with varying acyl chain length.
What are the official names of this protein?
Probable carboxylesterase 11, AtCXE11.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: VP6_ROTS1
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFNFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLRKLSAIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANIQQFEHIVPLRRVLTTATITLLPDAERFSFPRVINSADGATTWFFNPVILRPNNVEVEFLLNGQIINTYQARFGTIVARNFDTIRLSFQLMRPPNMTPAVAVLFPNAQPFEHHATVGLTLRIESAVCESVLADASETLLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: ISPT_WOLSU
Sequence: MRELNELKHLAIIMDGNGRWAQERGKQRVRGHEKGAETIREITMFCSKSDISFLTLYAFSTENWKRPKTEVDFLMRLLSDYLKKEAEVYLKNNIRFKAIGDLSRFSSRLLDEIETLTQKSASCSGLTQVLALNYGSKDEIIRATQKMIEAGVEVSEENLSRFLDTAFAPDVDMLVRTGGDYRLSNYLLWQSSYAELFFTPTLWPDFTAGELAIQIEEFKRRKRRFGGI
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RS14_ECOSE
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DF295_ARATH
Sequence: MASKITFVFLVVVVINCAMMLSMPTAEAHNFLPCVITNDCEYHHCSSGTVLCVNRQCHCSRSSTHQTKLDNLKKMDYAKKCKWTKDCDPRMRFTCVSGSYMCFDGLCTCTN
What are the official names of this protein?
Defensin-like protein 295.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MENH_SERP5
Sequence: MLATKVLQQGEADRPWLIWLHGLLGNNNEWRVIASRCPEWPSLAIDLPGHGDSVAVVCTSFDDISAQISATLQMHGIERYWLVGYSLGGRIAMYHACHGEPRGLQGVIIEGGNPGLADAAQRELRLAHDTAWAERFRREPLAQVLADWYQQPVFANLSAVHRDALIDARSDNAGAAVADMLEATSLGTQPCLAPQLQQLAVPLVVLCGADDHKFQQLTRDAGLPLRIVPQAGHNSHLANPQAFAAELRNFLVNPG
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: APAH_NEIG2
Sequence: MAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPKSLETLQFCIRHENSVQIVLGNHDLYLLAVGCGEGALKRSDTIEPILKHPDGGKMLDWLRAQPLLIREGGRVMIHAGILPQWRIAKAESLAGEAEAELRGKKYVKFFSKMYGNKPAAWDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDHTIIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: TRPD_SHEB8
Sequence: MSTNPIQPLLDVLYQGKSLNREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISGAADAMRAAAKPFPCPERNNNPLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCFLFAPHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALHGNTQVAELKDGDIVEYQLTPADLGVPLAQITDLEGGEPAQNALITEAILKGRGTEAHANAVAINAGCALYVCGIADSVKAGTLLALATIQSGKAFELLSQLAKVSGEALVNGQEKGR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: EPHB1_RAT
Sequence: MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3.  During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline.  This probably requires repulsive interaction with EFNB2.  In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation.  May also regulate angiogenesis.  More generally, may play a role in targeted cell migration and adhesion.  Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively (By similarity).  Involved in the maintenance of the pool of satellite cells (muscle stem cells) by promoting their self-renewal and reducing their activation and differentiation (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 1, ELK, Tyrosine-protein kinase receptor EPH-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane. Cell projection, dendrite.
Protein: BIOD1_YERPE
Sequence: MTKRWFITGTDTDVGKTVASCALLQAATAQGYRTAGYKPVASGSQMTADGLRNSDALALQANSSQRLGYSQVNPFTFLEATSPHIASESEGRAIPLTALSQGLRQLEPSADWILIEGAGGWFTPLSPQATFADWVQQEQLPVIMVVGVKLGCINHALLTAQAIQHAGLTLAGWVANEVTPAGRRQAEYQATLTRMITAPLLGIIPYLSDIEENPVTTRRDLGHYLDLTVLRAAEREAVNM
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 1, DTB synthetase 1, DTBS 1, Dethiobiotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLA_PAEPO
Sequence: MTIFQFPQDFMWGTATAAYQIEGAYQEDGRGLSIWDTFAHTPGKVFNGDNGNVACDSYHRYEEDIRLMKELGIRTYRFSVSWPRIFPNGDGEVNQEGLDYYHRVVDLLNDNGIEPFCTLYHWDLPQALQDAGGWGNRRTIQAFVQFAETMFREFHGKIQHWLTFNEPWCIAFLSNMLGVHAPGLTNLQTAIDVGHHLLVAHGLSVRRFRELGTSGQIGIAPNVSWAVPYSTSEEDKAACARTISLHSDWFLQPIYQGSYPQFLVDWFAEQGATVPIQDGDMDIIGEPIDMIGINYYSMSVNRFNPEAGFLQSEEINMGLPVTDIGWPVESRGLYEVLHYLQKYGNIDIYITENGACINDEVVNGKVQDDRRISYMQQHLVQVHRTIHDGLHVKGYMAWSLLDNFEWAEGYNMRFGMIHVDFRTQVRTPKESYYWYRNVVSNNWLETRR
What is the function of this protein?
BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.
What are the official names of this protein?
Beta-glucosidase A, BGA, Amygdalase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: RSMA_MESFL
Sequence: MKVEAKKKFGQNFISDQNLINKIVSILGNDKDQLIIEIGPGTGALTKLLAQKYNKVVAIEIDTDMEPILKKEITNDNFELFLSDVLLVDFEKLIKEKRQHENQKVSIISNMPYYITSEILFRTLNVSDKLTKAVFMMQKEVAIRVCSYKGENNYNNLSVACEFYADKKYEFTVPKHMFYPVPKVDSAIISLTFNNKYTEQIKDKDKFLTFLRKIFNNRRKTILNNLSNVTNDKTKANEILDNLNIDKSLRPEVVGLEDFIRIYNKTR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGD1_HUMAN
Sequence: MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
What is the function of this protein?
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells.  Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis.  May act as a regulator of the function of DLX family members.  May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.  Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.  Plays a role in the circadian rhythm regulation.  May act as RORA co-regulator, modulating the expression of core clock genes such as BMAL1 and NFIL3, induced, or NR1D1, repressed.
What are the official names of this protein?
Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF.
Protein: SYA_SULIY
Sequence: MKASEEEYRLNFFIKNDFKRKICKSCKTPFWTRDEKKEYCSDIPCTDYYFFDINIKSQPLTVKEAREKFLSFFEKRGHTRISPKPVLARWREDLYLTIASIVDFQPHVTSGLVPPPANPLVVSQPSIRLEDIDNVGITFGRHLTTFEMAAHHAFNYPDHYVYWKEETTAYATEFFTKELGIPEEELNFKESWWEGGGNAGPCLEVTVGGLELATLVFMQYKITDNGNYTPLKLKIVDTGYGVERIAWITQKTPSAFHAIYGNLVYKFFNKIGVAYIDETLLKVASRFAGKIDPDNPDTIKIHRQMVSKELGIDIKAVEEELDRAAKVFQILDHTKTIMLMLADGLVPSNSGEGYLGRLVIRRALKVLRLLKSDVRLYELVKEQIDFWKEDFPQVLKNKDYILDAVELEQQRFEKILEKVPSIASTLARKSEITTEDLIQVYDSNGIPPDLLEEELKKKSVKFELPRNFYALVAKRHQTSTIKSAYDKVKLPKDMLEYITALQPTEKLYYKDQYMRSFEGKVLGVYKNYLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEVIDTQKVNDVIVHILKEEPSTIKVGDNVRGEINWERRYRLMRHHTVTHVILAAAKKVLGEHVWQAGAEKTPEKGRLDITHHKTLTEEEVKLIENYANSVISDRRQVKPLEMNRMEAEMKYGVSIYEGGVPNSATIRLLEIKDWDIESCGGTHVSNTSEIGAVKIINVERIQDGVIRLEYVAGPALVDYIRETQAKIVEASKIIGTSPDQLTSRLRRILNEIEEKNNLIIQYRRIIETELLNNLKPYEINSNKIYIIEGLGDEEENKEILRKLTSTDNTIAISISDNRLQIATSKNMRVDKIVEELLKGGGKGGGKGTFANVILNSKKSKEEIIEIVRKSL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y315_SHEB5
Sequence: MTKKIELAQIRVLFLGIWHFLLHLRRRLVEDQINIRAGHLAYVTLLSLVPMVAVTMSMLSAFPVFKGIRGQIEGFVYENFLPAAGDTVQVYINEFVGNASKGTAVGIAALVVVAIMLISAIDKSLNNIWRTKEKRSVVVAFSMYWMVLTLGPVLVGASLVASSYVISLKVFEAEALSGMLPIFIARLPMLFSVAAFLLLYMVVPNQKVKFLHALLGAIVAALLFELGKKGFALYVTQFPSYEAIYGALATIPIVFVWVYLSWMIVLLGAEITAAMPEYLDYESSSDDETALNAKPLADASQGDSSSVLTSAEVTALKAVAKSE
What are the official names of this protein?
UPF0761 membrane protein Sbal_0315.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KRP85_STRPU
Sequence: MPGGSSGNDNVRVVVRCRPLNSKETGQGFKSVVKMDEMRGTVQVTNPNAPSGEPPKSFTFDTVFAPGAKQTDVYNQTARPIVDAIIEGYNGTIFAYGQTGTGKTFTMEGVRSQPELRGIIPNSFAHIFGHIAKEQENVRFLVRVSYLEIYNEEVKDLLGKDQQHRLEVKERPDVGVYVKDLSAFVVNNADDMDRIMTLGNKNRSVGATNMNESSSRSHAIFTITLERSDMGLDKEQHVRVGKLHMVDLAGSERQTKTGATGQRLKEATKINLSLSTLGNVISSLVDGKSTHIPYRNSKLTRLLQDSLGGNAKTVMCANIGPAEYNYDETISTLRYANRAKNIKNKAKINEDPKDALLREFQKEIEELKKQISESGEGLDDDEESGSEESGDEEAGEGGVKKKRKGKNPKRKLSPEIMAAMQKKIDEEKKALEEKKDMVEEDRNTVHRELQRRESELHKAQDDQKILNEKLNAIQKKLIVGGVDLLAKSEEQEQLLEQSALEMKERMAKQESMRKMMEEREQERMDIEEKYSSLQDEAHGKTKKLKKVWTMLMQAKSEVADMQAEHQREMEALLENVRELSRELRLSMLIIDSFIPQEFQEMIEQYVHWNEDIGEWQLKCVAYTGNNMRKQTPVADKDKSLAYGEADLSNVFLTYNLEGGGMKYKPSQGKSGRPKTSSGRPKTGKKKQASMASSIDALLQ
What are the official names of this protein?
Kinesin-II 85 kDa subunit, KRP-85/95 85 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CLPP_STRR6
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_GEOSL
Sequence: MARYTGPSCRLCRRENMELFLKGERCYTDKCAIKRRNYPPGQHGQGRPKVSNYGVQLREKQKVRRIYGILEKQFRSYFQEADRLKGVTGENLLSLLERRLDNVVYRLGFAASRTEARILVRHNHFTLNGKKANIPSIQLRAGDVVELKEKSRKIACINESLDAVVRRGIPQWLELEKDAYKGVVKTLPVREDITMPIQEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS4E_METMP
Sequence: MAIKGPRKHLKRLAAPANWQLPRKVKTFTVRPSPGPHSMDKSLPLLLVVRDVLKYADNAREAKKIIQTGKILIDGLKRKEYKHPAGLMDVLSIPEMDETYLVLFDESGRISLKKTDKTDVKLCKIVNKTVVKGGNIQLNLHDGRNQIVKVSDAAKAEEDVYKTGDSVLISIPEQSIAGHVAFGEGKLAYITGGKHVGEFAKIVEVENRALYSDIVTLENKDGEKFKTVKPYVFIVGQDEPVISM
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: BVMO_PARL1
Sequence: MSSVQSSQTQKNDDAEVFDALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGGIWYWNCYPGARVDSHIPIYEFSIEELWRDWNWTERFPAWDELRRYFHYVDKKLDLSRDIRFGMRVSAAEFDEARDQWVIRTTDGTVVRARFFILCTGFASKPYIPNYKGLESFAGESFHTGLWPQEGASFTGKRVGVVGTGASGVQVVQEASKDAAHLTVFQRTPILALPMQQRKLDVETQQRMKADYPEIFRIRRETFGGFDILRDERSALEVPPEERCALYEKLWQKGGFHYWIGGFSDILTNEEANRTMYDFWRDKTRARIKNPALADKLAPMEPPHPFGVKRPSLEQWYYEAFNQDNVSLVDVREMPIVEIVPEGVLTSDGLVELDMLVLATGFDAVTGGLTQIDIHGTGGITLKEKWTEGARTYLGFATSGFPNMLFLYGPQSPSGFCNGPTCAEMQGEWVVDCLKHMRENNKGRIEATAQAEEEWAQLLNSIAGMTLFPRADSWYMGANIPGKPRQLLNFPGVPIYMDQCNTAAAKDYEGFVLD
What is the function of this protein?
Catalyzes a Baeyer-Villiger oxidation reaction, i. e.  the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH as an electron donor.  Besides cycloalkanones, can use cyclic alpha,beta-unsaturated ketones as substrates, leading to enol-lactones.  Can also act on methylated cycloalkanones and methylated cycloalkenones with high enantioselectivity in some cases.
What are the official names of this protein?
Baeyer-Villiger monooxygenase, BVMO.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: MDH_ECOL5
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVIECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RPGR_MOUSE
Sequence: MAESESLVPDTGAVFTFGKTKFAENIPSKFWFKNDIPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLRFAVQLIACGGCHMLVFATPRLGTIDEPKFEDVYEPYISTGSFSINDLSPRSSLNRSLSARLRRRERERPPCSASMVGTLPPLEGTSASTSAYFYPSSPPFHLSVNNYPEKSPSESMEPLDSDYFEDKMNKDTETENSSAVDSENFGETNDILNMTHMMTTSSNEKLLDFSPIQKQQNQDTFEKVMESTPCTENEDSYEYEEMSKIKEVTVYKQYLAKGIYMIRPAEILEAFSDEEVGNGLDQVEEPRVFTDGKGLQSKQVGKESDEEIVSEKKTEVMEVADVKKIRESEENSKSDSLFDDLPDKTMNSESEDNKDIAEERRSSEQNMTFDSETELVEEPDSYMECERHSEQDSAEELEQPKLVEYSSEEKDEKDEKDDDEVETENLWYDRNCTEQETENVFRATRFFPKFDLKHDHLSGIPEEQEGPEDSEGNVVVEQVVQAQKENLEFEGDRKEAKAEAPSDVITEKEAPQLSETVKPEEGEMDEEISILNVEDTVEEERKEGEKEIVEEGSIPETEGSETIDITDEKLDEVLKEEDSASLLQRALREYNENPKGHMYDRVKSSSSEILGGNDPTSKDIKKAKKISFFNRMSLTGQKLMQNTNDPLPEIKPIGDQIALQSDKKDANQNHMGQNLQDSTTPNMEGKSKSCTIL
What is the function of this protein?
Could be a guanine-nucleotide releasing factor (By similarity).  Plays a role in ciliogenesis (By similarity).  Probably regulates cilia formation by regulating actin stress filaments and cell contractility (By similarity).  May be involved in microtubule organization and regulation of transport in primary cilia (By similarity).  Plays an important role in photoreceptor integrity.  Isoform 5 may play a critical role in spermatogenesis and in intraflagellar transport processes.
What are the official names of this protein?
X-linked retinitis pigmentosa GTPase regulator, mRpgr.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Note=In the retinal photoreceptor cell layer, localizes at the connecting cilium (PubMed:29899041). Colocalizes with WHRN in the photoreceptor connecting cilium (PubMed:22323458). Colocalizes with CEP290 in the photoreceptor connecting cilium (PubMed:16632484). Colocalizes with RPGRIP1 in the photoreceptor connecting cilium (PubMed:15772089). SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: MURE_RALSO
Sequence: MTAVPTSERAPIAARLAPVLDWLRAHVPAGADLTSDTRKLKTGDVFVAYVLGNVRQRGDGRPHIPQAIEAGVSAVLAEAHGYVVPADAPARILPVDGLSELAGPLAAQWYAVPGPDALRVIGVTGTNGKTSCSQWIAQALSRQGERCAVVGTLGTGFVDALVATGFTTPDAIQLQHSLADLHRAGARAVAMEVSSHGLEQGRADGTRFDIALFTNLTQDHLDYHGTMAEYELAKARLFGWPGLRAAVINRDDAAGGRLLAGLRAGIEAVEYGIDGEAAAQRGAGHWLRATNVRAHRTGTTFDVDGSFGRATVHSPMVGLFNVSNQLGVLGVLLMAGVPWQDALARLEKLQPVSGRMERFGGEDGPLVVVDYAHTPDALEQTLRALAPITGARGGKLWAVFGCGGDRDPGKRPQMGAIAERLAQHVVLTSDNPRSEDPQLILDMIADGMEDPRLAIQIEDRAAAILHAVRHADVHDVIVVAGKGHESTQEIAGRKRPFSDQEHVRLALAARGVNA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.