PharMolix/UniProtQA huggingface dataset:
Protein: UB2J1_MOUSE
Sequence: METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALLAIIGFMPTKGEGAIGSLDYTPEERRALAKKSQDFCCEGCGSAMKDVLLPLKSGSGSSQADQEAKELARQISFKAEVNSSGKTIAESDLNQCFSLNDSQDDLPTTFQGATASTSYGAQNPSGAPLPQPTQPAPKNTSMSPRQRRAQQQSQRRPSTSPDVLQGQPPRAHHTEHGGSAMLIIILTLALAALIFRRIYLANEYIFDFEL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) and is essential for cells to recover from ER stress.  Plays a role in MAPKAPK2-dependent translational control of TNF-alpha synthesis.  Acts also as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the E3 ubiquitin-protein ligase RNF26.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 J1, E2 ubiquitin-conjugating enzyme J1, Non-canonical ubiquitin-conjugating enzyme 1, NCUBE-1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: CYAY_BURMS
Sequence: MSDTDYLTRAEAVLAAVERSVDAANDGDADIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFVDGAWRDTRSGDEFFAALTGYATQQAGMPIAFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: Y1038_METMA
Sequence: MPIILENISVFYSRNTPLEISALKDVNLRIEKGEFVGILGEKGAGKSTLIKLFNGLLRPDSGRITVNGLDPSSKKVKSRVGMVFQQPADQLFCRTVYEEIAFGPLNFGYSRKETEERVFEALEAASLERSMLSRDPLSLSGGEMQRVALAGALALRPDYLVLDEPITGLDPAGKKEILETLKKIKGQGTTIITVTHNLKGFFPLLERIVLIKEGRISFQGSRKEYMETENVPLPPVASMMRELHSRGIQVNPAVFTVEEALKEILRVKSMIEKEKAEKERAEKQTKK
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein MM_1038.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PER43_ARATH
Sequence: MVWANAKMRLALSLVTVFFGISLANLEVGFYSNTCPQAESIVKRVVSGAALSDPNLPAILLRLHFHDCFVEGCDGSILVNNGAISEKNAFGHEGVRGFEIVEAVKAELEAACPGVVSCSDIVALAARDAISLANGPAYEVPTGRRDGRVSNMSLAKDMPEVSDSIEILKAKFMQKGLNAKDLVLLSAAHTIGTTACFFMSKRLYDFLPGGQPDPTINPTFLPELTTQCPQNGDINVRLPIDRFSERLFDKQILQNIKDGFAVLQTDAGLYEDVTTRQVVDSYLGMLNPFFGPTFESDFVKAIVKMGKIGVKTGFKGEIRRVCSAFN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 43, Atperox P43.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HPCL1_RAT
Sequence: MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
What are the official names of this protein?
Hippocalcin-like protein 1, Neural visinin-like protein 3, NVL-3, NVP-3, Visinin-like protein 3, VILIP-3.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: HSCA_SALSV
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPHLPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVDPQDVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HYDL_STRHA
Sequence: MNARADRAGDTVHRVPVLVVGGSLVGLSTSVFLGRLGVRHMLVERHAGTSVHPRGRGNNVRTMEVYRAAGVEQGIRRAAATLAGNHGILQTPSLVGDEGEWLLRDIDPGGGLARFSPSSWCLCSQNDLEPVLLDHAVELGGEIRFSTELQSFEQDPAGVTAVIKSRRSGEHTTVRADYLVAADGPRSPVREQLGIGQSGPGDLFHNVSVTFRSRRLAEFVGDRHFIVCYLTNPEADGALLPVDNRENWVFHAPWYPRAARPLEDFTDERCADHIRRAVGVPDLDVEITGKAPWHAAQRVARQYRAGRVFLAGDSAHEMSPTGAFGSNTGIQDAHNLAWKLAAVLGGWAGDGLLDTYDAERRPVAEATTARAAARSAEHSHPGFAPPPGTSGGPQGGILNVALGYRYPGGAVLGADPATPVVPEALTLAGEPGSRAPHLWMSRRGERLSTLDLYERSPVLLSDADAGAPDAWHESAVRLAEELSVPLTSYRVGRSAGADLTPEDDVNWTARHGTPPGGAVLVRPDGFVAWRSQEPVPAEETEPTLRHVLTTVLSLG
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii.
What are the official names of this protein?
Putative polyketide hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: PACA_CHICK
Sequence: MSGNVYKTLLTLLVYGLIMHCNVYCSPDRWTPVPGAKLEEEVYDEDGNTLQDFALRAGAPGGGGPRPRWGRCTALYYPPGKRHADGIFSKAYRKLLGQLSARNYLHSLMAKRVGGASSGLGDEAEPLSKRHIDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRVAYL
What is the function of this protein?
PACAP plays pivotal roles as a neurotransmitter and/or a neuromodulator.
What are the official names of this protein?
Glucagon family neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPB2_IIV3
Sequence: MNQLNQKTKLDKHLSSDNRAKIVADYFKTNGLVKHQIETFNHFISKGLKTIINNESSIKYQSHDNYSLKFTNIYVEYPSIIDDDRTIRDLYPQEARNKDLSYTGNVCVNVIEMVENKEGKPPQISEQYRVPIAKIPIMLGSDVCHLSKYTPLENEQINGHSQADQGGYFIINGKERVLISQVRKAYNKPVCFVKSTSQKEDVLICEMRSMCEETFHSTSVQVKMIKNKIMVSLKLKRKLIDIPVGIVFKCLGYNPDQMGSKFRSLFNLPPEYEKYIDAIKNDCLEEFAYGIAVSAADGDNSDSGGESGGEEEADQEEHIVKVFRNMSTSVDKDGGMAATGITIEDVQKSLDMDLFPHLGITSTRKQRVDLLAFMVKKYLLTLTRKIPVDNRDDYNHKRVETAGELYSFLFRLLYKKFQKTCITQIRNRKPDISNFLRTSGITTGILYSFSSGYWGVQRNTYIRTGVSQVVNPKVSLLANYSSLRRVVIPESKDGKEAKTSEIRQIHPSSSFLVCPVETPEGKGVGTVLNMAVFCQVTTGISTCEIMDQIDSFGVDLKCHCTIKDPNNCLLLLINGSPYGNGHANVIHRLNFLNDTNISIVVNRALGVIEIFSDAGRFIRPIFDLDKICNFEGEIVPSFKWFLDNQLIRYIDINEAAANSIAIELRDLSTNPNTRYNLMELDPCGMFGIVAGIIPFPDRTQSARNCFYSSMVKQAIGFVPCHNLKTETVSHTLNYPQKPLVTTSFAEYNQLNEYPNGINAIVAIACYTGYNQEDSIILNKSSIDRGLFGTITYNTFTAQEKKNGIIEERIEIPSNAIKIRDCNYGLVGPDGIVRLRQRVKKGDVLICKVTIKNKNQDEKLVDSSVIVQHGEEGYVDRIVDNVIDGCRIVKVVIGQMRTPEIGDKFCSGMAQKGTCGMIFPQEDMPFTASGMTPDIIINPNCIPSRMTINQIISTVMGKLYTVNPNPRFRNGNSFQENSNTILKELCHHLKLNGFDPSGSEVMYSGFTGERIQSTIFMGPTYYHRLKHMVKDKMHARSHGQVTTLHRQPNCGRSQGGGLRFGEMEKDCILVHGATQFLNERMFLNSDPFQIDVCKDCGMMSSTSKKCHHCGSINVKRCNIPYSCKNLLQELNGMGIKTKIDL
What is the function of this protein?
Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase II subunit RPB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ATPH_SOLTU
Sequence: MNPLISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YQJI_SHIFL
Sequence: MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCGGRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQNPQMKRALDNFKAVLDLRVNQSDISDAQIKKIIAVIDRAAFDITQLD
What are the official names of this protein?
Uncharacterized protein YqjI.
Protein: CYSD_HYPNA
Sequence: MRTRHGAFLLLARPATERAHTPEQDQYTLPTLTHLDRLEAESLHILREVAAECEKPVMLYSIGKDSAVMLHLAMKAFYPARPPFPLLHVDTGWKFREMIAFRDRKVKELGLELLVHMNEDGVREGVGPFTHGSAYHTDVMKTAALKQALDKYGFDAAFGGARRDEEKSRAKERVISFRSAGHRWDPKRQRPEIWNLYNTRMHKGESLRAFPLSNWTELDIWQYIRREGIELVPLYLAAPRPVVTWNDTLIMVDDDRVPAEIAAKAEVKSVRFRTLGCYPLTGAVESTATTLDDVIQEILLTTTSERQGRAIDKDQTASMEKKKQEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: FMT_FRATO
Sequence: MKKLNIIFAGTPDISAQVLKDLYKSQHNIQAVLTQPDRAKGRGKKVQFSPVKEVALANHTPVFQPLSFKKNPEVLEQIKQLKPDVIVVIAYGIIVPQEFLDIPRYGCLNIHVSLLPKWRGAAPIQRAIQAGDTKTGVCIMQMDAGLDTGDILNTLEIEIQETDTSQTLHDKFAKLSIKPLLETLEKIEIIKPEPQQGEPTYAHKITKQEGLIDFTKSAWRISCHIRAFTPWPGAYFILDDEAIKVGEFEILYQNTDNRKAGTIIDIYRSGFDIATSDKIIRFRQLQFPNKKMLNIVDILNGKDLDKYIGYKLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MRAY_GLUOX
Sequence: MLFNLIAAHDTSHGGFFNLFHYLTFRSGCACLTALVISLALGNPFIAQLKRIQREGQPIRTVGPERHILEKAGTPTMGGMLILIALFSATLLWADLTNGFVWAVMLTTAAFGAVGFADDYLKLSKRNTTGVSKRTRLGCEFLASLIAGIWLQSLTPPELRNMVAFPFVKDVLLPLGYAFPIFAMITITGFGNAVNFTDGLDGLAIVPVVIAALVFALISYLVGNHVFADYLQLHPVPGTGELAVFCAALIGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAVAVATKHELVLCIVGGVFVAETLSVVIQIFWFKRTGRRVFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SDCS_STAS1
Sequence: MNNLNKGDMRRSQYLMFFSNKKENKSYNVGQLVGLILGPLLFVLTLLLFQPDNLSDKGVFVLAITLWIATWWITEAIPIAATSLLPLILLPVGHVLNPEEVSAQYGNDIIFLFLGGFILAIAMERWNLHTRVALRIINTLGTSTGRILLGFMIATGFLSMFVSNTAAVMIMIPIGLAIIKEANELKHGDTKPESISKFEQALVLAIGYAGTIGGLGTLIGTPPLIILKGQYQSAFGEEISFAKWMIIGVPTVIVLLFLVWIYIRYIAFKHDMKTLPGGQDLIRKKLSELGKMKYEEKVVLIVFLLASFLWITREFLLKHWTFTSEVADGTIAMFISVLLFLIPAKNKEKHKRIIDWEVAKDLPWGVLILFGGGLALAKGISESGLANWLGEQLKLIEGVSPLVIVLVITIFVLFLTEITSNTATATMILPILATLSVAVNVHPLLLMVPAAMAANCAYMLPVGTPPNAIVFGTGKISIKKMASVGFWVNLLSIVVIVLVVYFLVPPVLGIDVTQPLPLK
What is the function of this protein?
Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient.
What are the official names of this protein?
Sodium-dependent dicarboxylate transporter SdcS, Na(+)/dicarboxylate symporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_CLOBM
Sequence: MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKREMKGEEINNADVAASFQKSVVDVLVDNTIKACISKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYIKGRRTSLDINAVPNLKLGER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHUR_XENLA
Sequence: MCGGCVQQEYPDRGSTCLETGSYLLNYVSCVQCNKRDFVLIVNKTAAEEDGEEIITYDHMCKNCHHVIAKHEYTFSVVDDYQEYTMLCMLCGRAEDSVSVLPDDPRQMAPLF
What is the function of this protein?
Transcriptional activator that mediates FGF signaling during neural development (By similarity).  Plays a role in the regulation of cell movement (By similarity).  Does not bind DNA by itself (By similarity).
What are the official names of this protein?
Protein Churchill.
What is the protein family that this protein belongs to?
Belongs to the Churchill family.
Protein: CLPP_DEIRA
Sequence: MEVMSVIPYVIEQTGRGERSYDIYSRLLKDRIIFVGTPVESQMANSIVAQLLLLDSQNPEQEIQMYINCPGGEVYAGLAIYDTMRYIKAPVSTICVGMAMSMGSVLLMAGDKGKRMALPNSRIMIHQGSAGFRGNTPDLEVQAKEVLKLRDTLVDIYHKHTDLPQEKLLRDMERDYFMSPEEALKYGLIDQVIDQTRENRGGEE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIC_SALDC
Sequence: MSITAKSVYRDAGNFFRNQFITILLVSLLCAFITVVLGHAFSPSDAQIAQLSEGEHLAGSAGLFELVQNMTPEQQQILLRASAASTFSGLIGNAILAGGIILMIQLVSAGHRVSALRAIGASAPALPKLFILIFLTTLLVQIGIMLIVVPGIIMAIVLALAPVMLVEEKMGVFAAMRSSMRLAWANMRLVAPAVIGWLLAKTLLLLFAPSFAVLTPNVGAVLANTLSNLISAVLLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRSA1_LISMF
Sequence: MTKLKKVMISVIAATLLLLAGCGSSAVVKTDAGSVTQDELYEAMKTTYGNEVVQQLTFKKILEDKYTVTEKEVNAEYKKYEEQYGDSFESTLSSNNLTKTSFKENLEYNLLVQKATEANMNVSESKLKTYYKTWEPDITVRHILVDDEATAKEIQTKLKNGEKFTDLAKEYSTDTATSTNGGLLDPFGPGEMDETFEKAAYALENKDDVSGIVKSTYGYHLIQLVKKTEKGTYAKEKANVKAAYIESQLTTENMTAALKKELKAANIDIKDSDLKDAFADYTSTSSTSSTTTSN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PURA_PHOPR
Sequence: MANNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRNNVKCIIGNGVVLSPDALMKEMGPLEARGIPVRERLFLSEACPLILPYHIALDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKEAFAEKLKEVMAYHNFQLEHYYNAEPVSYDEVLASVMAQADVLTAMVIDVTQELDDARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELDDAVGEHLGVKGNEFGATTGRKRRCGWFDAVAMRRAVQINSISGFCLTKLDVMDGLKEIKICTGYKTQDGKTLSVSPMAADAYENLELIYETMPGWSENTFGAKTLDALPQAALDYIARIEELTGVPIDIVSTGPDRNETIIKVHPYGE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_VIBC3
Sequence: MQKMRTLGEFIVEKQHDFPHASGELSSLLASIRLAAKIVNREINKAGLADIIGASGNDNIQGEEQQKLDLYANEKFKAALEARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVSPVGTPPTQEDFLQPGNKQVAAGYVIYGSSTMLVYTTGNGVNGFTYDPSLGTFYLSHENMRIPENGKIYSINEGNYIRFPTGVKKYIKFCQENVPEDGRPYTSRYIGSLVADFHRNLLKGGIYLYPSTQSHPNGKLRLLYECNPMAFLIEQAGGLASDGVHRIMDIKPTELHQRVPFFVGSKNMVHKVEEFLETYPD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BURCJ
Sequence: MPRRREVPKREVLPDPKFGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYK_MYCGI
Sequence: MTSPDSPDDIPEQFRIRQAKRERLLAEGREPYPVKVDRTHTLAELRQAYPDLEPDTKTGLKVGVAGRVIFARNSGKLCFATLQEGDGAQLQVMISFAEVGQESLDAWKADVDLGDIVFVHGEVISSRRGELSVLADSWQIVSKALRPLPVAHKELNEETRVRQRYVDLIVRPEARTIARQRIAVVRAVRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDADLYLRIAPELFLKRCVVGGFDRVFELNRNFRNEGADSTHSPEFAMLETYQAYGTYDDSATVTRELIQEVADEAIGTRQVPLADGTEYDLDGEWQSLQMYPSLSEALGEEITPATPAEKLWQIADRLGVEIPRDRGYGHGKLVEELWEFTVGDTLWAPTFVRDFPVETTPLTRPHRSIEGVTEKWDLYVRKFELATGYSELIDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGMPPTTGTGMGIDRLLMALTGLSIRETVLFPIVRRHSN
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS75_YEAST
Sequence: MMSDQENENEHAKAFLGLAKCEEEVDAIEREVELYRLNKMKPVYEKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRDFSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLIKDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAEAQRDLEDEEGESGLSADGDSEDDDGSLGEVDLPLSDEEPSSKKRKV
What is the function of this protein?
Histone chaperone which acts as a cofactor stimulating histone H3 acetylation by RTT109 (PubMed:21256037, PubMed:17320445, PubMed:31387991, PubMed:29300933, PubMed:19172748).  Preferentially stimulates histone H3 'Lys-9' acetylation by RTT109 (PubMed:21256037, PubMed:31387991, PubMed:29300933).  May also stimulate histone H3 'Lys-56' acetylation by RTT109 (PubMed:17320445).  Assembles nucleosomes (in vitro) (PubMed:19172748).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 75.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHSE_PARXL
Sequence: MAVFTAVTEPQLAEWMRHYDLGDVVEFRGISSGIENSNFFLTTTRGEYVLTIFEKLTAEQLPFYLDLMRHLAAHRVPVPDPMPREDGALFGLLQGKPAAIVTRLEGAPELAPGVEHCIEVGQMLARMHLAGRDYPAYQPNLRSLPWWKETVPTILPFLEGGQRELLSSELAYQEAFFASADYAALPEGPCHADLFRDNAMFAHAEPGTGHEVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLATGKLDAARTEAMLRAYQTVRPFTAEENRHWGDMLRAGAYRFWVSRLYDFHLPRAAELLKPHDPGHFERILRERLSGVALPGIHTSCN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: Y1479_MYCS2
Sequence: MVRSDNDTWDLASSVGATATMVAAGRAVVSQDPGGLINDPFAAPLVRAVGIEALTMLADGKFDIEKVLPESAARVRANIDEMAVRTKFFDDYFMDATGRGVGQAVILASGLDSRAYRLPWPDGTVVYEIDQPDVIEFKTRTLADLGAEPTCERRTVSIDLRDDWPAALRAAGFDPSAPTAWCAEGLLIYLPPEAQDKLFDDIHHLSAPGSTVATEFVPALKDFDPEKARQATETLTRMGVDIDMPSLIYHGERHSASDYLETKGWQMDSAARATLFTRYGLPAPGHDDDDPLGEIIYISGTLR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MSMEG_1479/MSMEI_1443.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: HRCA_XYLF2
Sequence: MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELGLLNSPHTSAGRVPTAHGYRMFVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILSAMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFADNEVQNRVIEPRRVYEPGELERVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTGQTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISLVTAPYAAHGQVLGVLGVIGPKRMAYDRVIPLVQVVAQVLGTALEPPTMP
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: CARR_MYXXA
Sequence: MKPPMDLDSLLTQTPAKDNAALERVLAAARGELALRRPVRRWRTQAVGLMAASAGLGLLAAVVLLAVGAVTGPLLLARAPLLAMLVGTSAVCAWGALSPKGRWMRRLGVGLAVVSAAALVLARGAPHSPPSFPGWVCTVSHLAIGVVPLVVALFALRGAFFQPLRAVVAGLSVGSTGALLGELACEQDWRHVLSHHLLAWVVITVVLVVISKSLKPRSYAP
What is the function of this protein?
Negative regulator of the carotenoid synthesis regulon.  It is probably inactivated by protoporphyrin IX in the presence of blue light.  Inactivation of CarR leads to loss of negative control over the carotenogenesis protein CarQ.
What are the official names of this protein?
Carotenogenesis protein CarR.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.