PharMolix/UniProtQA huggingface dataset:
Protein: SC6A8_MOUSE
Sequence: MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPAKGDGPAGLGAPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
What is the function of this protein?
Creatine:sodium symporter which mediates the uptake of creatine (PubMed:12439290).  Plays an important role in supplying creatine to the brain via the blood-brain barrier (PubMed:12439290).
What are the official names of this protein?
Sodium- and chloride-dependent creatine transporter 1, CT1, Creatine transporter 1, Solute carrier family 6 member 8.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RFA1_CRIFA
Sequence: MHQPGSHQIQPIDSLTPFLGGKWWIRARVADKSDIRTWNKPTSQGKLFSFTLIDESAAIRATVFNDAVDTFEPLVVNGQVYYFSGGQVKNANRRFSNVNNDYELTFDRASEVILARQDSSAAALPMQRYNFVPIELLKQREVGSLVDVLGVVLKVDEISSITQKSTGRELIKRNVKIGDMSAAVEVTFWNDEAKAWNYPVGTVVALRQLKVGSFDGVTLSSTYQTKIDVNPADLPDVKKLATWYVSTGGANVVSLSSQGLGAGGGGGGEGNRGRKYLDEIQSEGIGRGAKPEYVDVRCVPIYFKQDAQWYDACPTCNKKVTEEGAQGDRFRCEKCDATVVPTQRYLVSIQVTDNVSQVWLTLFNEAGVEFFGMEASELKRRAQEDPLYIAKLAQARMNRPVVMRLRVKEETNANAMTGEESDRLRMSVVRISEFMPVAGTTEETRRRLAQNLRSECDDILRCIEAYV
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
What are the official names of this protein?
Replication factor A 51 kDa subunit, RP-A p51, Replication factor-A protein 1, RF-A protein 1, Single-stranded DNA-binding protein P51 subunit.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DMAC2_MACFA
Sequence: MAAPWVSLRLVAPMWNGTRGIHRLGGAVVPEGNQKKERKMLQFLNNHFYDVEALRGYLLQREMSKVHLKNRSFTWLEEQHGPYSAGAFFILKQGGAVKFRDKEWIRPDKYGHFSPEFWNFREVPVEAVDASDCEINYEGLDNLLLLKELQSLSLQRCPHVDDWCLSRLYPLADSLQELSLAGCPRVSERGLACLHHLQNLRRLDISDLPAVSNPGLTQILVEEMLPNCQVVGVDWAEGLKLGPEERPQDTASPVPA
What is the function of this protein?
Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Involved in the assembly of the distal region of complex I.
What are the official names of this protein?
Distal membrane-arm assembly complex protein 2, ATP synthase subunit s-like protein.
What is the protein family that this protein belongs to?
Belongs to the ATP synthase subunit s family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSD_PSEMY
Sequence: MKQRLFILSQYLLPHHLLSRLIGCVAECRIGWLKNRLIAWFAKQYRVDMSEAQVEDLSAYEHFNAFFTRALKAGARPLDETPGAILCPADGAISQLGVIEHGRLFQAKGHSFSATELLGGDAERAAPFMGGQFATVYLSPKDYHRVHMPLAGTLKEMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASVETVWAGLVTPPKRELKSTRYDAESRGPIELAKGAELGRFKLGSTAIVLFGPQQVQWAEELTAGSTVRMGQLLGNAQL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_HELPJ
Sequence: MQEIENLHQSVLLQEVLQAFTPLEEGILIDCTLGLGGHSKAILSQKPHLKLIGIDKDKFAQEIAKERLKEFEGRYNLLSGGFAKRFKEALEIHGERIKGVLVDLGVSSLQLDDDNRGFNFRSHALDMRMDLESELNAQKVINSYPVVALEKIFRDYGEIKEYKKIAHKIAERRAKKPFKDAKDLSEFLSSLSKNKKIHPATLVFQAVRIEVNSELEELKEFLQCARNLKEAILCVISFHSLEDALVKNAFKDYAKNCICDPSSFKCACSNNHALGAILTKKPITPSPEEIKNNRRSRSAKMRVFQFKP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_POLAQ
Sequence: MNKLTHFDDSGQAHMVNVGDKPATHRIAIATGKITMLLETFKMVETGNHKKGDVLGIARIAGIQASKRTADLIPLCHPLALTHVSLEFRLDSTTSTISCKVRAETTGPTGVEMEALTAVQVALLTIYDMCKAVDRGMVMGDIKLLEKSGGKSGEWKLA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TCPR1_HUMAN
Sequence: MPNSVLWAVDLFGRVYTLSTAGQYWEMCKDSQLEFKRVSATTQCCWGIACDNQVYVYVCASDVPIRRREEAYENQRWNPMGGFCEKLLLSDRWGWSDVSGLQHRPLDRVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAIDFPATYTKDKKWNSCVRRRKWIRYRRYKSRDIWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHSNPEGSSWSLLDTPGEVVQISCGPHDLLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSENGVMHISVGVSVVWAVTKDWKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGMNDQVWGIGCEDRAVYFRQGVTPSELSGKTWKAIIAARECDRSHSGSSSSLLSAGCFFGDEVRGSGESAPSDTDASSEVERPGPGQILPAEPLDDSKNATGNSASGLGAGRTAEDTVEDACPAEGSREARPNTHPGPAPTPAELPWTNIDLKEAKKVPSHSAAGFPETTSLSSLGLLPLGLEEPYGVDDHPLWAWVSGGGCVVEACAMPRWFTVQAGLSSSVHMLSLSITPAQTAAWRKQIFQQLTERTKRELENFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRLALEQFTGHDGVRDSILFIYYVVHEEKKYIHIFLNEVVALVPVLNETKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVQGRPSPQAIWSITCKGDIFVSEPSPDLEAHEHPLPCDQMFWRQMGGHLRMVEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKCVHIYENQRWNPVTGYTSRGLPTDRYMWSDASGLQECTKAGTKPPSLQWAWVSDWFVDFSVPGGTDQEGWQYASDFPASYHGSKTMKDFVRRRCWARKCKLVTSGPWLEVPPIALRDVSIIPESPGAEGSGHSIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASISIGACYQVWAVARDGSAFYRGSVYPSQPAGDCWYHIPSPPRQRLKQVSAGQTSVYALDENGNLWYRQGITPSYPQGSSWEHVSNNVCRVSVGPLDQVWVIANKVQGSHSLSRGTVCHRTGVQPHEPKGHGWDYGIGGGWDHISVRANATRAPRSSSQEQEPSAPPEAHGPVCC
What is the function of this protein?
Tethering factor involved in autophagy.  Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes.  Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
What are the official names of this protein?
Tectonin beta-propeller repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TECPR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
Protein: P26_LIYV9
Sequence: MNNFPEIFDDESTCDYDKEIDHQELSDTFWCLMDFISSKHGKSVADINSGMNTLINIRKSLNGSGKVVSITDSYNKTYFHSQRGLTNVDSRINIDILKIDFISIIDDLQIIFRGLIYKDKGFLDSADLLDLDKKTTTRKFQEYFNILKIKIIEKIGMTKTFHFNIDFRNTISPLDKQRKCSISSSHKKTNRLNDLNNYITYLNDNIVLTFRWKGVGFGGLSLNDIKI
What are the official names of this protein?
Protein p26.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Found in plasmalemma deposits.
Protein: ITR1_ASCSU
Sequence: EAEKCTKPNEQWTKCGGCEGTCAQKIVPCTRECKPPRCECIASAGFVRDAQGNCIKFEDCPK
What are the official names of this protein?
Trypsin inhibitor, ATI.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7S_BACCQ
Sequence: MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKNVQEQMAVILGEDGELEPFTALGDEA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BRUA1
Sequence: MPDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAQHVTYARNITDVDDKINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNLQPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPSAMNARKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLEPFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNDGLPQLGEWGDNTVRDHWAGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDLNSWAAITALRQAFKVRDVAALGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDELLQEGVQLKDSKDPATGERITTWDVVG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC4_ECOLX
Sequence: MGIPNLTKGDAMRAAKHYRQLLSIDFNIEALAFVPGPDGTRGRRIHVLGREVRDRPGLVEYLSPAFGSRVALDGYCKANFDAVLHLAYPDHQQWGHA
What are the official names of this protein?
Protein ParC.
Protein: 3MGH_STAEQ
Sequence: MIYLDFINQQTTQTAKALLGVKIIYQDDYQTYTGYIVETEAYLGIQDKAAHGFGGKITPKVTSLYKKGGTIYAHVMHTHLLINFVTRTEGIPEGVLIRAIEPDEGIGAMNVNRGKSGYELTNGPGKWTKAFNIPRSIDGSTLNDCKLSIDTNHRKYPKTIIESGRIGIPNKGEWTNKPLRFTVKGNPYVSRMRKSDFQNPDDTWK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: ATG26_DEBHA
Sequence: MLPKEDKVNSNHFKGVNDAHKTSLYKRLSSSVIPPLTFLNQNPASPNNEEVPGNNEANKDEKTFSDDEDIAHPIGSVGSSNNFLSFLYAGMGKLSDLKGNDASNANEAKDSKLNDNLRSSRNEQANEPEYRREYKLDYDIDESEEDDIESTRDENTLKPKTEDTSVHSKLDPEERLENVVNMLFDDHDESTTALASDPSKGTVFQQSVLKNFDPFRIQQTELLKLKDITLSTEEDESEEQKLKKKFFRLKVADKLKRVFELNDDDYFYGNYNVWLVRDVLLQGHIYLTKESILFFTFLPKRHNTISASKGTTGGFQHHDDSHDVIQSGSLGMKTALYGDTVFSTPLTHRFWVILRNETITVYHSPTDLYFPITLIDLKSCVRAEVIEKGRNDNASPRPDLHRNDSQEVSSGDEEVEFSNMLNSNYQLEDNSENVSGGYWFKVVTKKKTHKFHSDSLYSARQWVNNIVKVVFQLHNSNANNEVIMKIPINDVLSFDLNEVFGASEKNSDSNGGEEKPKVLNVKYLENGSKGRYALSASRMKKELKNKTKKKMKKNSGNEPDELLSENTYFLLFKDGDEVFSTLNEIVNENHHSSNIFRNRHNSISKKYTSEKGSNWNRPFTHKDEEIHIPRAISTLTTDHFQNSIIDQIEEASHRNTHTQNTDLASPRSECGLTHSVSTSPQSKIRKFGKTLITPSKIFSNKSRTESEKSTPDRSQTTSPVQGINLSLSGLKDLNMAFEASQKNYEVSCTRYSHTEENSTNSPSNFQNNTLSKADALSPQIKSPQPLEAGPLNLTDPSEYEDNKKKNSTLSSIGKSIKAMSSIRSKLAAVNHYEQLDENDTYFIRDVSAREVDTRHFQERFSFNNKKQLIASYHCHIIRAVPVFGKVYLGDSEICFRSMLPGVSTRMILPLIDVDTCSKEKGSNIAYSGLVLVIRGYDELFMEFSVQSARDDCLAMILRQLEKNRESGNESSDDNKSAQHGKSGCFQKTPSSAETTKSSNEIKLAQWRIENARLKLFEDKINAAAGLHVPIVLEDSPFYKTEIRPSTSFNFTLLTIGSRGDVQPYIALGKGLLNEGHNVTIATHSDFEEWIVGHGIKFKTIAGNPVELMSLMVTHGSMSLSFLKEASSKFRGWIQELLDTSWKACQGSDILIESPSAMVGAHIAEALGIPYIRAFTMPWTRTRAYPHAFIVPDKKKGGSYNYITHLMFETVLWKGISSQVNKWRRESLGLPRTNLYRLAQYDIPFLYNISPTIFPPSVDFPDWVKVTGYWFLDEGAADDFEPSKELVEFMNKARADDKKVVYIGFGSIVVEDAKSLTKAIVEAVLNADVRCILNKGWSDRNSSPAKDNAEPEVELPEEIYNSGSIPHDWLFPKIDAAVHHGGSGTTGATMRAGIPTIIKPFFGDQFFYSSRIEDIGAGIGLKKLNARSLCTALKTATSDAKMITKAKKISERLKQENGVLNAIEAIYYELEYARSLILAKQHENTKHDLKSGTQTPVVNETNEYFDSDTYDADHDSDKESDHDQTYEQDNHSDYDVANDDNMTEIVEPSLEDGNDTVRIAPDSGNDNTTVTDANK
What is the function of this protein?
Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).
What are the official names of this protein?
Sterol 3-beta-glucosyltransferase, Autophagy-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: TRI29_MOUSE
Sequence: MEGADACRSNGASPEARDTRSPPGPSGSLENGTKADSKDTKTTNGHSGEVTEGKTLGSALKSGEGKSGLFSSNEWRRPIIQFVESVDDKGSSYFSMDSAEGRRSPYAGLQLGASKKPPVTFAEKGELRKSIFSEPRKPTVTIVEPGEVRRNSYPRADSSLLARAKSGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPLHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDDVEKWQKEKDRIKSFTTNEKAILEQNFRDLVRELEKQKEEVRAALEQREQDAVDQVKVIVDALDERAKVLHEDKQTREQLHNISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNCKDDLLNVCMRHVEKMCKADLSRNFIERNHMENGGDHRYMNSYTSSYGNEWSTPDTMKRYSMYLTPKGGGRTSYQPSSPSRLSKETNQKNFNNLYGTKGNYTSRVWEYTSTVQNSEDMPTVQGNSSFSLKGFPSLLRSQVPKAQPQTWKSGKQTLLSHYRPFYVNKGSGIGSNEAP
What is the function of this protein?
Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract.  Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation.  In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited.  Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.
What are the official names of this protein?
Tripartite motif-containing protein 29.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome. Note=Colocalizes with intermediate filaments.
Protein: ERP27_BOVIN
Sequence: MEAMPSRCLFLLFLSTCKLSPEVVAEVQESSDGPGAQEPMRLTDVQAAMEFIAAAEVAVIGFFQDSEVPAVSLIHSVVQNFQDVSFGISTASEVLAYYNITGNTISLFRLVDNKQLDLKGEDFESMDATKLSRFIESNNLRLVTEYNAITAIGLFNSMIPIHLLLIMNKASSEFEENLHRFQEAAKLFQGRILFILVDSGVKQNEKAISFFKLKMAELPALAIYQTLDDKWDTLPITEVLVEQVQNFCDGFLKGKGLRQNHEAKEKTSKVEL
What is the function of this protein?
Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates.  Binds protein substrates via a hydrophobic pocket in the C-terminal domain.  May play a role in the unfolded stress response.
What are the official names of this protein?
Endoplasmic reticulum resident protein 27, ER protein 27, ERp27, Inactive protein disulfide-isomerase 27.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ATPF_ADICA
Sequence: MRSLSEIIAPSSYWTLAGTIGLNTNIFEINLINLILVLGILFYYGKGVLINLLENRERTILNTIQDAEERHKEATEKLQRARLRLQQAEMKADEIRIIGLTKMDRERRDLVDAADNDLRELEESKNYAIRFEKQRAIEQVRQQVSRLASERAFESLNGRLTNEFQLRMIDYHIGLLRAMANKST
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1084_FINM2
Sequence: MEVVIVTGMSGAGKSASSHILEDLGYYTLDNMPPSLLLSFIDLTTKSKKKINKIACVVDIRGGEFFADLMKSITLLKNQSIDVKILYLDASDEILIRRYKEHRRPHPLAINGNISQGISNERELLSEVRNSADSIINTSNLTLGELRRKILYVFSLKDVDTKLAISVVSFGFKHGILLDADLVFDVRFLPNPYYIEELKKSSGLNTDIKDYVFGFDEANEFLDKLVDMVEFLIPKYSKEGKTNLVIGIGCTGGKHRSVAIAQALTARLEGNGEKVYVSHRDQKFW
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein FMG_1084.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LEUC_SYNJB
Sequence: MSERTLFDKVWDAHTVRILPSGQTQLFIGLHLIHEVTSPQAFAMLRERHLPVLFPERTVATVDHIIPTDNRARPFADPLAEEMIQELERNCRQYGIRFYNSGSGRQGIVHVIAPEQGLTLPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLATQTLALSKLKVRRIEIHGKLGPGVYAKDVILHIIRKLGVKGGVGYAYEYGGSAIEAMSMEERMTLCNMSIEGGARCGYVNPDAVTFEYLRGREFAPQGSDWEEAVAWWKSLASDGNARYDDVVVFQAADIAPTVTWGITPGQGIGVDERIPAPEDLPESERELAKEAYAYMDLQPGDPIVGTPVDVCFIGSCTNGRLSDLREAAKIAKGRRVAPGVKAFVVPGSERVKQEAEQEGLREIFEAAGFEWRDPGCSMCLAMNPDRLVGRQISASSSNRNFKGRQGSPSGRTLLMSPAMVAAAAVSGKVVDVRTLL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TIPRL_ARATH
Sequence: METVVDKDVLKSSGAELLPDGRRGLRIHDWEIETLRGTILTSLAVEEWEKKLKTSHLPEMVFGENALVLKHLGSNTKIHFNAFDALAGWKQEGLPPVEVPAAAQWKFRSKPSQQVILDYDYTFTTPYCGSEVVEKDKETVEAKANPKGEATLQWENCEDQIDLAALSLKEPILFYDEVVLYEDELADNGVSLLTVKVRVMPSSWFLLLRFWLRVDGVLMRLRETRMHYRFGEDEAPTVLRENCWREATFQSLSAKGYPVDLAVWSDPSSISQRLPVIKHTTQKLKIPSKV
What is the function of this protein?
May be involved in the regulation of the TOR signaling pathway.  Indirectly activates the PP2A phosphatase via interaction with its suppressor TAP46.  Could play a role in cytoskeleton functions.
What are the official names of this protein?
TIP41-like protein.
What is the protein family that this protein belongs to?
Belongs to the TIP41 family.
Protein: CRYAA_FELCA
Sequence: MDIAIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: CYB_REDFU
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLMLQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYMFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILILMPTASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRHO_STRTD
Sequence: MAKPIRVLLYYKYVPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEEEQAFKKMFVRYKKEIVHLGLEDNNFDSDINPLETTGAYLSPKEFKDALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDHKEEFMDKRVVVYCTGGVRCEKFSGWLVREGYKDVGQLHGGIVTYGKDPEVQGELWDGKLYVFDERIAVDVNHVDPIVVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSENDLSQEEVVSRLAAIGESLDVTPA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: TBB_COPC7
Sequence: MREIVHLQTGQCGNQIGAKFWEVVSDEHGIERDGLYKGNNDLQLERISVYYNEIGASKYVPRAVLVDLEPGTMDSVRSGPLGSLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEYPDRMMCTYSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICFRTLKLSTPTYGDLNHLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMTGFAPLTARGSAQYRAVTVPELTQQMFDAKNMMAASDPRHGRYLTVAAVFRGKVSMKEVEEQMQNVQNKNSAYFVEWIPNNVLTAQCDIPPRGLKMAVTFLGNSTAIQELFKRVSDQFTAMFKRKAFLHWYTQEGMDEMEFTEAESNMQDLVAEYQQYQDATVEEEGEYEDEVLEDEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LPTD_NEIMH
Sequence: MARLFSLKPLVLALGLCFGTHCAAADAVAAEETDNPTAGESVRSVSEPIQPTSLSLGSTCLFCSNESGSPERTEAAVQGSGEASIPEDYTRIVADRMEGQSQVQVRAEGNVVVERNRTTLNTDWADYDQSGDTVTAGDRFALQQDGTLIRGETLTYNLEQQTGEAHNVRMEIEQGGRRLQSVSRTAEMLGEGHYKLTETQFNTCSAGDAGWYVKAASVEADREKGIGVAKHAAFVFGGVPIFYTPWADFPLDGNRKSGLLVPSLSAGSDGVSLSVPYYFNLAPNLDATFAPSVIGERGAVFDGQVRYLRPDYAGQSDLTWLPHDKKSGRNNRYQAKWQHRHDISDTLQAGVDFNQVSDSGYYRDFYGNKEIAGNVNLNRRVWLDYGGRAAGGSLNAGLSVLKYQTLANQSGYKDKPYALMPRLSVEWRKNTGRAQIGVSAQFTRFSHDSRQDGSRLVVYPDIKWDFSNSWGYVRPKLGLHATYYSLNRFGSQEARRVSRTLPIVNIDSGATFERNTRMFGGEVLQTLEPRLFYNYIPAKSQNDLPNFDSSESSFGYGQLFRENLYYGNDRINTANSLSAAVQSRILDGATGEERFRAGIGQKFYFKDDAVMLDGSVGKKPRNRSDWVAFASGSIGSRFILDSSIHYNQNDKRAENYAVGASYRPAQGKVLNARYKYGRNEKIYLKSDGSYFYDKLSQLDLSAQWPLTRNLSAVVRYNYGFEAKKPIEVLAGAEYKSSCGCWGAGVYAQRYVTGENTYKNAVFFSLQLKDLSSVGRNPADRMDVAVPGYITAHSLSAGRNKRP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Determines N-hexane tolerance and is involved in outer membrane permeability.  Essential for envelope biogenesis.
What are the official names of this protein?
LPS-assembly protein LptD, Organic solvent tolerance protein.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CAPSD_TYCS2
Sequence: MPKRTGDILMSSPLSKFRRKLNFDSPYTSRAAAPTVQGIKRRSWTYRPMYRKPRMYRMYRSPDVPFGCEGPCKVQSYEQRDDVKHTGVVRCVSDVTRGSGITHRVGKRFCIKSIYILGKIWMDENIKKQNHTNQVMFFLVRDRRPYGTSPMDFGQVFNMFDNEPSTATVKNDLRDRYQVMRKFHATVVGGPSGMKEQCLLKRFFKVNTHVVYNHQEQAKYENHTENALLLYMACTHASNPVYATLKIRIYFYDAVTN
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).