PharMolix/UniProtQA huggingface dataset:
Protein: VATG3_MOUSE
Sequence: MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQMEKDFRLKQAKIMGSQSHLSDEIEEQTLEKIKELNGSYNKCMESVIKQLLSMVCDMKPEVHVNYRATN
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
What are the official names of this protein?
V-type proton ATPase subunit G 3, V-ATPase subunit G 3, V-ATPase 13 kDa subunit 3, Vacuolar proton pump subunit G 3.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
Protein: NIKE_BRUSU
Sequence: MSLISADNIVKIYQSHSLVGASARKTVLHDISISIGQGETVALLGRSGCGKSTLARLLVGLERPTSGEVRFRGVPLTKLDRSGMKAFRREVQLIFQDSPGAVNARSSVRAIIGEPLRHLTSLDETRREERIQELLRLVELPPEIADRLPAQVSGGQLQRICIARALAVNPKLIILDEAVSNLDIHLQASALALLTKLQQEGGIAYLFVTHDLRLVQKFAARCLVMDEGQIVEEIKTADLDSMRHPASRLLREAVLPPLPVRAVETN
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROA_NOCSJ
Sequence: MSTQHDEHDAAGATGVADQVVAAAERARAASHGLALATRAEKDAALQAMAEALLTREPEVLAANGEDVARAEANGTPPNIVDRLRLTQERVAAMAQGLRDVAALPDPVGEVLRGSTLANGLEMRQVRVPFGVVGMIYEARPNVTADAAGICLKSGNAVLLRGSSSARSSNAAIVAALRDAIAGTGLDPDVVQQVPGDSHDSVKALMRARGHVDVLIPRGGAGLIRSVVEESTVPVIETGVGNCHVYVDRAADLDKALAIVLNAKTHRTSVCNAAESLLVHADLADTFVPRVVAALQEAGVTVHGDERFQAEDGVLPATDEDYGQEYLSLDISAAVVPDLDGAIAHIRRWSSQHTEAIVTEDLAAARRFTAAVDSAAVLVNASTRFTDGGEFGFGAEIGISTQKLHARGPMGLTEMTSTKYVVTGDGHVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_PHYAS
Sequence: MKKYEIMYILRPNLDNNEVKKINDHLESVFSKKPSTILEKKEIGLKDLAYPINNHKKGYYYWFITQTDNEAVLEFNRIVKITEEVIRFIIIKE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MRE11_XENLA
Sequence: MSSSSSSLDDEDTFKILVATDIHLGFMEKDAVRGNDSFVAFDEILRLAQDNEVDFLLLGGDLFHDNKPSRRTLHICLEQLRKYCMGDRPIEFEVLSDQSVNFGYSKFPWVNYQDNNLNISLPVFSVHGNHDDPTGADALCALDILSSAGLVNHFGRATSVEKIDISPVLLQKGHSKIALYGLGSIPDERLYRMFVNKQVMMLRPREDESSWFNLFVIHQNRSKHGPTNYIPEQFLDEFLDLVIWGHEHECKIAPTRNEQQLFYVSQPGSSVATSLSPGEAEKKHVGLLRIKGKKMNMQKIPLQTVRQFFIEDLVLSDYPDIFNPDNPRVTQEIETFCIEKVEAMLDTAERERLGNPRQPDKPLIRLRVDYTGGFEPFNTLRFSQKFVDRTANPKDIIHFFRHKEQKDKKDSITINFGKIDSKPLLEGTTLRVEDLVKEYFKTAEKNVQLSLLTERGMGEAVQEFVDKEEKDALEELVKFQLEKTQRFLKERHIDAEEEKIDEEVRKFRETRKTNTNEEDEEVREAIQRARTHRSQAPDVEMSDEDDDALLRKVSLSDDEDVRASMPARGRGRGRARGGRGQSTTTRGTSRRGRGSASADQPSSGRATKATGKNMSILDAFKPSSRQPTARNVAKKTYSEDIEDDDSDLEEVSFTPSSVIESRRTSSTSTSYSRKSTQPQSQATKAHFFDDDDDEEDFDPFKKSGPSRRGRR
What is the function of this protein?
Involved in DNA double-strand break repair (DSBR).  Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity.  Also involved in meiotic DSB processing.
What are the official names of this protein?
Double-strand break repair protein MRE11.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRS3_AGAAN
Sequence: MAFLKKSLFLVLLLGLISLSICEEEKRENEVEEEQEDDEQSELRRSLWSKIKEMAATAGKAALNAVTGMVNQGEQ
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria.  Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
What are the official names of this protein?
Dermaseptin-A3, DRS-A3, Dermaseptin AA-3-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PO210_RAT
Sequence: MARASLIQPGLWALLLLQAVGPAVAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWSSTRPEVASIEPLGSSEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEANGFSDSHNALRILTFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLLVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPDPQGDPARPVAVLTQDTSRVTAMQMGQSNLVLGHRSIRMQGASRLPNSTIYVVEAGYLGFTVHPGDRWVLETGHLYAVTIEVFDRSSNKVYPSDNIRIEAVFPAEFFEVLSSSQNGSYHHVRAIQSGQTTISASLTSVVDQDGGVHVLQVPVWNQQEVDIHIPITLYPSILTFPWQPKTGAYQYTIKAHGGSGNFTWSSSSYMVATVTVKGVMTTGGDTGLSVIRAHDVQNPLHFGEMKVYVIEPSSMEFAPCQVEARVGHTLELPLTISGLMPGGSSEVVTLSDCSHFDLVVEVENQGVFQPLPGRLPPGPEHCSGVKVRADAQGSTTLLVSYTHGHVHLGAKITLAAYLPLKAVDPSSVAVVTLGSSKEMLFEGGPRPWVLEPSKFFRNVTSEDTGSISLSLLGPPASRNYQQHRVLVTCQALGEQVIALSVGNRPSLSNPFPAVEPTVVKSVCAPPSRLTLMPVYALPQLDLSCPLLQQNKQVVPVSSHRNPLLDLGAYDQQGRRFDNFSSLSIQWESFRPLLASIEVDQPMQLVSQDDGNGQKKLHGLQTVSVHEASGTTAISATATGYQQSHLSAAGVKQLRDPLVPVSASIELILVEDVRVSPEEVTIYNHPGVQVELHITEGSGYFFLNTSTQDIINVAYQDTRGVAMVHPLFPGSSTVMVHDLCLTFPAPAKATIHVSDIQELYVRVVDKVEIGKAVKAYVRVLDFYKKPFLAKYFTFMDLKLRAASQIITLVTLDEALDNYTATFLVHGVAIGQTSLSASVTDKSGQRVSSTAQQIEVFPPFRLIPRKVTLIIGAMIQITSEGGPQPQSNILFSINNESVAAVSSAGLVRGLMVGNGSVLGVVQAVDAETGKVIIVSQDHVEVEVLQLQAVRIRAPITRMRTGTQMPVYVTGITSNQSPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEVSIRLSPQYNFAMNVHGRVKGRTGLRVVVKALDPTAGQLHGLGKELSDEIQIQVFEKLRLLNPEVEAEQILMSPNSFIKLQTNRDGAAILSYRVLDGPEKAPIVHIDEKGFLVSGSGIGVSTLEVIAQEPFGTNQTVLVAVKVSPISYLRISMSPVLHTQHKEVLTALPLGMTVTFTVHFHDSSGDIFHAHNSDLNFATNRDDFVQIGKGATNNTCIIRTVSVGLTLLHVWDVEHLGLSDFVPLPVLQAITPELSGAVVVGDILCLASVLISLGGVSGTWSSSAGNVLYVDPKTGVAIARDAGPVTVYYEIAGHLKTFKEIVVVTPQKIVARRLHATQTSIQEATASKVTVSVGDRSSNLLGECSSAQREAIEALHPESLISCQLQFKQDVFDFPARDIFSVEPGFDTALGQYLCSVTMHRLTDKQLKHLNMKKTSLAVTASMPSSRTSVEKVGAEVPFSPGLYANQAEILLSNHYPSSEVKIFGAVEILENLEVRSGSPAVLASVKEKSFGLPSFITYTVGVLDPTAGSQGPLSTALTFSSPATNQAITIPVTVAFVLDRRGPGPYGASLLSHFLDSYQVMFFTFFALLAGTAVTIIAYHTVCAPRELASPLALTPHASPQHSPHYLASSPTAFNTLPSDRKASPPSGLWSPAYASH
What is the function of this protein?
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
What are the official names of this protein?
Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nuclear envelope pore membrane protein POM 210, POM210, Nucleoporin Nup210, Pore membrane protein of 210 kDa.
What is the protein family that this protein belongs to?
Belongs to the NUP210 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RS18_SALDC
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HSSS_STAAT
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTIDQKGHKTFYGEPFREDTLSQNAINNVLNNQDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVNQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSL
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GEND1_ACAGO
Sequence: SFRFFEEIIMRLATLLGLSVLHLALCVLTCTAHHPGLEKSRVSYENMGDEENAEERSCVHERETCSKVRGPLCCRGECICPIYGDCFCYGS
What is the function of this protein?
Putative ion channel inhibitor that may also act as a antimicrobial peptide.
What are the official names of this protein?
U1-theraphotoxin-Agm2a, U1-TRTX-Agm2a, Genicutoxin-D1-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CYCK_CLITE
Sequence: HEPCGESCVFIPCITTVVGCSCKNKVCYN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide cter-K.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: METE_VIBHA
Sequence: MTTTTHILGYPRIGEKRELKFAQEKYWRGEIEQTELKQVGATLREKNWATQAEAGLSFATAGDFAWYDHVLTTTLLLGHTPKRHANGFPDLDTLFKVGRGQSQAGCGCSGAAASDMTKWFNTNYHYIVPEFSKDDSFEVSWPQLFEEVNDAIKLGHNVKPVLLGPLSYLYLGKEIEEDFDRLTLLPRLLTAYQAILSKLANQGVEWVQIDEPILSLELEEKWGDAFKLAYQVIRSDVKVLLTTYFDSVSDTLDKIVELPVDGLHIDLSASPEQLDEVVEKLPQGWVLSAGVVNGRNVWRSDLSAQRERLQPVKDKLGDNLWVASSCSLLHSPVDLDLEPALSDEVKSWFAFAKQKVTEVALLGRALDGDHNAILVCDTYSQPIKDRKTAAHVNKPHVQARLNSISASLTERSAPYAERAAHQAEVLGLPLLPTTTIGSFPQTSEIRVQRSAFRSGQLSTDDYHQALKGHIADAVRRQEALDLDVLVHGEAERNDMVEYFAENLAGFQTTKFGWVQSYGSRCVKPAIVVADIEREKPITVEWSTYAQSLTNKQMKGMLTGPVTILCWTFPREDITRKAIADQLALALRDEVSDLQQAGINIIQIDEPAIREGLPLKKRDHKAYLQWAVDAFKIAAASAKPETQIHTHMCYSEFNEIIDSVAALDADVITIETSRSNMELLKAFEDFNYPNEIGPGVYDIHSPNIPSEEWIEELIKKAAEKIPAQRLWVNPDCGLKTRNWSETEAALANLVSAAKKLRAELV
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RN2A_LITPA
Sequence: MFTTKKSMLLFFFLGTISLSLCEQERGADEDDGVEMTEEEVKRGIMDTVKNVAKNLAGQLLDKLKCKITAC
What is the function of this protein?
May have antimicrobial activity against the Gram-negative bacterium E. coli.
What are the official names of this protein?
Ranatuerin-2PLa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: KITH_STAAR
Sequence: MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHDLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CERS5
Sequence: MRVVFMGSPDFSVPVLEALHAHHEVVCVYCQPPRPAGRGKKDRPTPVQARAEELGLPVRHPKSLRTPEVQADFAALGAEVAVVVAYGLILPQPILDAPDRGCLNIHASLLPRWRGAAPIHRAILAGDDETGICIMQMEAGLDTGPVLMCEKTHIGAEDTVQDLHDRLSGMGARLILGAIEALDDLVPQPQPEEGVTYAEKIAKAEAGIDWSRPAAEIDRQIRGLSPFPGAWTMLGGERVKLLRCRLAEGQGAPGELLEGLVIACGSGAVEITLAQREGKRPMERDEFLRGFALPRGSLATAS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TRNL_SCHPO
Sequence: MTRDQRVCIFGEKKSTVRSVTFKAPKSNYDLTSWRIWEQAFRLNVSNSKKCFDTISGHRITLPTNARGLFTGYDYESKRHRIVIRGYDKFFNIDEVPITTWDALSQHTKGPYELTVKENGCIIFIAALPDGQIIVSSKHSLGIVEGQSVSHANVGERWLEKHLQSVGRTKQELAHELLRRDMTAVAELCDDEFEEHILPYTGNSRGLYLHGLNRNCPQFITASSCEVAEFAEQWGFMKVSSFFMDSIHELKAFLENASKDGKWNNRAIEGFVIRCHSDHSSLEQQSSNDFFFKYKFPEPYGMFRQWREVTKMLISGKKPSYTKYKKVTAEYITFCDKKFKEDEDAKRLYMSNKGIISLRDEFLVLSKLDLMHLSVSNDNDCGKEFTLLVPIATIGCGKTTVAKILEKLFGWPVVQNDNLPSGKGGPKRFAKAIIEEFRNGHSVVFADRNNHISNMRSTLQTDILALIDGVRFVALPFKHTPEVPEFVQNRVLQRGDRHQSIKVSEGVDKVKAIMNTFYKQYKPFDPAGNKHDANYDDIIELDPLIGSLENARRIVNYFKKNIPELIPNDPSDDDYAAALNYAVNEYVPTYRKTFGNDSKKIKNKITAEGITGSSTCFKKAPRYFGVLLDRKTVESSLVQVLTIANLQWQEAFSRYTLQDSFHITMIHESQKPVNSRIWEQYLQHMHDKNTTKMGNISFRITHLVWDDRVICFRVTMNENSVWYGKTCNPQLHITLGTSSSDVKAFESNFLLKKLRWQGDEVDSTDGNVRYLTVLPKIIIEGMLEPVY
What is the function of this protein?
Required for the splicing of precursor tRNA molecules containing introns.  The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction.
What are the official names of this protein?
tRNA ligase 1.
What is the protein family that this protein belongs to?
Belongs to the TRL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPG_COCHE
Sequence: MPSSTLIDHSPRNPNPSPPRITASNVILIDNYDSFTWNVYQYLVFEGAFVTVYRNDEITLDELIAKKPTQLVISQVPDTRKEDVALAIEPLRTSVAKSPFSACAWESCIFYSYGGTVDVTGQILHGKTCPLKHDGKGVFAGVPQDVPVTRYHSLAGTHGTLPDCLEISATIPANADAEIKEVIMGVRHKEYVIEGVQFHPESILTEHGRLMMRNFLKMQGGTWAENERLQKEAHAQAIGAAFSESAMVQRTDSRTHLQKIYDHRRAAVAEQKKIPSNRPVDLQAAYDSNLAPPQINFPERLRQSPFKLSLMSEIKRASPSKGIISLSTCAPAQARLYAKAGARPISVLTEPEWFKGSIEDLRAVRQSIEGMANRPALLRKEFIFDEYQILEGRLAGADTVLVIVKMLETELLERLLGLSDSVGMEPLVEVQNTDEMKIAVKLGAQVIGVNNRNLVNFEVDIGTTNRLIQMVPKETILCALSGIAGPKDVEAYIKDGVGAVLVGEALMRASDMSQFISELLGGPYKEVRASSSSPIVKISGTRSEAAVAAVEAGADLIGIILAPGLKRTVTAETALSISEAVHKTKKPNVSKSGLLADSKTASDFFDHGASRLLETISRALLVGVFRNQSLEYVLEQQRLLNLDVVQLHGQEPIEWAKLVPVPVLKAFNPQDHGIGTRGYHALPLLDAGSGGSGKQLGLSDVKAAFTKDDGIKIILGRGLEPDNVQTTLAGLDEYRDRVYAVDVSSGVEEDGQQSLDKIRSFVKAAKSL
What is the function of this protein?
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
What are the official names of this protein?
Multifunctional tryptophan biosynthesis protein.
Protein: ADDA_LEUCK
Sequence: MATRFTINQQRAVEETGHNILVAASAGSGKTTVLIERLIQKILSGISVENFLIVTFTNAAAKEMRERLEIAIEKRLRDANDGMKRFLQEQLLLLPAANISTIDAYALRLIENYYHVIGLDPQFRLLSDTAERDMMRQDVLDTVFEAFYDETHPQHENFIALVNNFGNPNQDDALRQAVLKLSDFAEARPDGQQWLKELDKNDLATANGLTQSQTYRLTILPMMIARLEQLLEIAQATQTNLSGVPELKKTQQAFDEIIAYLVNVQQALVDDDWDTLRGKLSQLPKVSLETKRSKGIKDEPELLALLAQATTVKNNILGAKSDLKNVIDTFFKFDQNDWQYVEKQATELVNTLVTLTQACQSAFTTAKRDAQLVDFPDLGALALEILNDDMTRKTVSGQFQEILVDEYQDINQLQETLLTKVSNGHNMYMVGDVKQSIYGFRQAEPTLFARKYRQFALPDNPDSRIELADNFRSQNNVTRVTNLIFTQLMDEKLGDIAYTGEAKLVPKANYPTDVTPVFNMTIIKQPNVTTSEDEDESQEFEKRQAQYAQLANQILSLRDTTIFDRKAEPAGMRPVQYGDIAILTRSKTGYIDLVATLRQAGIPTQVDSVGNYFQTMEVYLMLDVLRVIDNPHQDIPLAAILRSPMFGYSENDLAAVRLADKKHDYWSALTVFAQADQRSQTVIDLIKKWHQLAIQNDLVALIWAIFDDTSWLDYVAGMPGGAQRQANLHALYDYARTYQENTHAGLFRFIRYIEQLQENDGQLGEAPQEANEQAVRIMTIHASKGLEFPIVFLPEFDKSFNTQDLSGKMLIQKNAGIGLEYLQPEALVAMPTLKKLTVQQALKRQSWSEEMRLLYVALTRAEQQIYVVGTVKLDENEENQRLIALWQRAKETSGQFLAEDLRLSAKSYFDWLLISLARTKNDDLESWLGDGHLPHVLGPETTLDSQISVRFINESDVVIPEPQGNETKEITRASTYQAEDFARAKAILDYQYPFQQATRTAAYQSVSEMKRLFEDPDRANLKTLNVLENGQLQPANELVSDKLVLPTFMTDGSQKPSSAAVGTATHLMLQLLDFKQIQTHQSLTALRDDLVTQGRLTAPVAALIDIDQILNFLQTPFAQRLCLHADSLRREATFAMIMPANQIYEHVHDQASVLVHGIIDGYFIDKKTKSITLFDYKTDFVRHGRVEEDISKMMVRYRGQLTLYKQALMQEFPDYTFYEPQLIILNVGRVIPITTK
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: PGK_HALSA
Sequence: MAIRTLDDLAAANRAIGVRVDINSPLTAAGGLADDARLRAHVDTLAELLAADARVAVLAHQGRPGGDEFARLERHADRLDALLDAPVSYCDATFSTGARDAVADLAPGEAVVLENTRFYSEEYMAFAPERAADTALVDGLAPALDAYVNDAFAAAHRSQPSLVGFPEVLPSYAGRVMEAELDALSGVADTPTPRTYVVGGAKVPDSVEVAAHALSHGLADNVLVTGVVANVFLAATGVDLGRASTDFIHERDYGTEIARAADLLAAHNDALHLPVDVAVERDGARCELSTDALPPAGDEAVCDIGSDTVDAYADVLADSETVVVNGPAGVFEDDLFADGTRGVFDAASEVEHSIVGGGDTAAAIRRFDITGFDHVSTGGGAAINLLTDADLPAVAALR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_MYCGA
Sequence: MSDITKQPANNISSDDKKEVAKASAKSSVEGAKRKTFYKSRSRKLCHFCAKGILKVDYKDVNTLRKNLNSYAKIVSRRQSGNCNLHQRHVSNAIKKARIMALLPFVKD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ATOE_HAEIN
Sequence: MISRVSRFMTTFVSKYLPDPLIFAVLLTFVTFICAWGLTDSTPVDLVNMWGNGFWNLLGFGMQMALIVVTGNALATSPQIRKFLSTIASIAKTPAQGVVLVTFMGSIACIINWGFGLVVGAMFAKEVARRIKGSDYALLIACAYIAFMTWGGGFSGSMPLLAATPGNPVAHLMMSESNPQGIIPAVSTLFSGYNIFITLSLVICLPFITYMMMPKNGETKSIDPKLIAPDPTFDKKLDKDATLAEKMEESRFLAYTIGALGYSYLGMYFYKNGFNLTINNVNLIFLITGIVLHGSPMAYMRAIINATRSTAGILVQFPFYAGVQLMMEHSGLGGLITEFFINVANKDSFPLLTFFSSAFINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSTMAIAYGEQWMNMAQPFWALPALGIAGLGVRDIMGFCMTALIFTAPIFIIGLYFL
What is the function of this protein?
May be responsible for the uptake of short-chain fatty acids.
What are the official names of this protein?
Putative short-chain fatty acid transporter.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_STAES
Sequence: MRTPIIAGNWKMNKTVQEAKDFVNELPTLPDPKEVESVICAPTIQLDALVTAVKDGKAKGLKIGAQNAYFEESGAYTGETSPVALSELGVKYVVIGHSERRDYFHETDEEVNKKAHAIFNHGMTPIICVGESDEEREAGKANKIVGNQVKKAVEGLSDDQLKEVVIAYEPIWAIGTGKSSTSEDANEMCAHVRQTLADLSSQEVADATRIQYGGSVKPNNIKEYMAQSDIDGALVGGASLKVEDFVQLLEGAK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPL_HUMAN
Sequence: MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFLSFTDLKDGNLEAGS
What is the function of this protein?
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate (PubMed:33895133).  It prevents sialic acids from being recycled and returning to the cell surface (PubMed:33895133).  Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (PubMed:22692205, PubMed:33895133).  Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (Probable).
What are the official names of this protein?
N-acetylneuraminate lyase, NALase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialate-pyruvate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR110_MOUSE
Sequence: MFSQIISTSDIFTFTIILFVELVIGILGNGFIALVNIMDWTKRRSISSADQILTALAITRFLYVWFMIICILLFMLCPHLLTRSEIVTSIGIIWIVNNHFSVWLATCLGVFYFLKIANFSNSLFLYLKWRVKKVVLMIIQVSMIFLILNLLSLSMYDQFSIDVYEGNTSYNLGDSTPFPTISLFINSSKVFVITNSSHIFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKPPRDASTMAHIKALQTGFSFLLLYAVYLLFIVIGMLSLRLIGGKLILLFDHISGIGFPISHSFVLILGNNKLRQASLSVLHCLRCRSKDMDTMGP
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 110, T2R110, mT2r57, STC 9-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MRAZ_RICB8
Sequence: MNIFLSKFINNNIDKKGRVSVPANYRAVLGKEAFNGIIAYPSIRNNCIEACGISHIEKLRQMIESLDPYSEERDAFETIIFGEAVQLSFDGEGRVILPASLMQHAGIEDQVCFVGKGVIFEIWQPQNFKDYLASAQKLAHEKRLTLRNTN
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ASSY_BART1
Sequence: MKKWQNIRKVVLAYSGGLDTSIILKWLQSTLDAEVVTFTADLGQGEELELARRKAEMLGVKEIYIEDLREEFVRDFVFPMFRANTVYEGAYLLGTSIARPLISKRLIEIAKETGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWDFKSRTDLFEFARMHQIPVEKDQQGEAPFSVDANLLHSSSEGKILENPALPAPEYVHIRTLSPEDAPDQATRITLGFKKGDAVSINGKNLSPATLLAELNRYGRDNGIGRLDLVENRFVGMKSRGFYETPGGTILLAAHRAIESLTLDRGAAHLKDELMPRYAELIYYGFWFSPERKMLQAAIDLSQEHVEGEVTLKLYKGNVIVEGRQSKKSLYSSELVTFEDDQGAYDQRDATGFIKLNALRLRTLARRCQGNQEKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG80_BPML5
Sequence: MTTRGAVIQAAHYAETEARLQRDHIIVTMSVEMNRALPAEKASWVHEDGSPRFHFMQAANREYSRRGGKGGGHIGAVANALLANLKILEGDE
What are the official names of this protein?
Gene 80 protein, Gp80.
Protein: ORN_ALKEH
Sequence: MGFSEHNLVWLDLEMTGLDPDTDRIIEIATLVTDSQLNILAEGPVLAVRQSEQALAAMDEWNTRTHGESGLIERVRASHLDEAAAEAETLAFLRRWVPERASPMCGNSICQDRRFLYRYMPRLEAWFHYRNLDVSTLKLLANRWHPEVLQGFSKKATHQALEDIRESVAELRHYRAHFLRLPAAGAEGGGAAD
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.