PharMolix/UniProtQA huggingface dataset:
Protein: ACON_EMENI
Sequence: MITTRLARMGALAPKSRLLFGTRGMATVADLDKKVEMCNLEKGNYINYKKMSENLDVVRRRLTRPLTYAEKILYSHLDDPQNQDIERGKSYLKLRPDRVACQDATAQMAILQFMSAGMPSVATPTTVHCDHLIEAQLGGEKDLARANEINKEVYDFLASSTAKYNIGFWKPGSGIIHQIILENYAFPGGLMIGTDSHTPNAGGLAIAAIGVGGADAVDVMAGLPWELKAPKVIGVRLTGEMSGWTAPKDIILKVAGLLTVKGGTGAIIEYHGPGVNSLSATGMATICNMGAEIGATTSLFPFNDRMYDYLKATKRQQIGDFARSYAKDLREDEGAEYDQLIEINLSELEPHINGPFTPDLATPISQFKEAVKANGWPEELKVGLIGSCTNSSYEDMSRAASIAQDALDHGLKAKSIFTVTPGSEQIRATIERDGQLKTLEEFGGVILANACGPCIGQWDRKDVKKGTPNSIVSSYNRNFTGRNDANPATHAFVTSPDLVVALSIAGTLNFNPLTDTLKDKDGKEFKLKAPTGDGLPSRGYDPGRDTYQAPPTDRSSVDVAVSPSSDRLQLLAGFQPWDGKDATGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNAENGEANKIKNVFTGEYGAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGLAIITRSFARIHETNLKKQGMLPLTFSDPADYDRIPPDATVDLLCTELAVDKPMTLRVHPKDGASFDVKLSHTFNESQIEWFKDGSALNTMARKSGN
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle.  Also catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Aconitate hydratase, mitochondrial, Aconitase, Citrate hydro-lyase, Homocitrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEP4_MYXXD
Sequence: MTHSSLPGYFGPLFAVFLFVLGLCVGSFLNVVIARVPLDQSIVRPRSRCPRCGHVLAWYENIPLLSWLALRARCRGCGVPISVRYPLVELLTGLLFFACLRRFGWTYELVPALVLVSLLVPLAFIDLDHWILPLSMTVPGMLAGIALAFPLGMDAFRDALMGAAVGFLSFRMMEYVGWKVFQREALGAGDKYLVAMLGAFLTWRALLGVLLFASMQGAVVGILMLLATGRAGPRTENTQDEPAGDAPPLTMTWEFTQPGLPLWKRLLLVPVCLLVQPIPDAPLDEEGEEEEWVPERTSIPFGPWLALAGLELLLLGPWLSRVLPADIAMMLGGLP
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SERC_YERPE
Sequence: MTQVYNFSAGPAMLPVEVLRRAEQELRNWHGLGTSVMEISHRSKEFMQVAEESEKDLRDLLQIPANYKVLFCHGGARAQFAAVPLNLLGDRNSADYIDGGYWAHSAIKEAQKYCTPNVIDVTTHDNGLTGIQPMKQWKLSDNAAYVHYCPNETIDGVAINEQPDFGNKVVVADYSSSILSRPIDISRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHTALPSILDYKVLADNDSMFNTPPTFAWYLSGLVFKWLKEQGGLGEMEKRNQAKAELLYGAIDRTGFYRNQVAITNRSWMNVPFQMADASLDKLFLSEAEAQGLQALKGHRVAGGMRASIYNAMPIEGVKALTDFMADFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPO1_DICDI
Sequence: MENILNFNEPLDINLLDQIVSVLYNPLSNKNDIKAAQMVLGKFQEHPDAWSKVDTILETSKIVQTKFIALVIMDSLIKYRWKSLPREQCEGIKNYIVSLIIRLSSDPQTSSREKLLVNKLNLVFVQILKQEWTTNWSTFIPEIISSSKTNESLCENNMVILRLLSEEIFNFSEEQMTQTKIQTLKITFEKEFSLINDLCFYILENATRASLIKATLETLQRFLNWVPLHYIIEVNGGIAEPSKLVKLLLHKYFPEPLFRNSTLKCLTEIGNLNLGNQQYDAVFIAIIDKFMNQIKFIKPDPSKIPQDYEDGDQGERSFIHTVSLFLTGFFKSHLKIMENSLNIPYLTLAHEILVNISNIDELELFKICLEYWNFLSSNLYSDIATFTTTLLSTPPRLQLYKSVLSKVRVVLIDHMAKPEEVIVVEDENGNIVRETTKDTDSLTLYESMRETLIFLTHLDSENTQHIMLEKLQTLISGREFTFQRLNTLCWAIGSISGAQNKEQEKRFLVTVIKDLLELCQNKKGKDNKAVIASDIMYIVGQYPRFLKDHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKISKQCKRKFVVLQVEESQPFINELLNQLSTTIAHLEQSQIHTFYEAVGYMIASSSDAAFREKLVNKFMELPNHSWLQIMGAASVKVESLLTVEVARDILNLIKTNNRAAMSLENCYITQISKIYLDLLNVYRTYSDHISRNPNIYRETLGQAMRSVKKETLKLLETFIEKSSDKQVIYSNFLQPLLEAVLGDYRTNIPETRDPEVLSLMTAIITSLKQLVHPEVPKILEAVFETTLSMITKNFEDYPYHRINFFNLIRAINSNAFTVFHNLHPQQFKLLIDCVVWAFKHTERNISETGLHILKELIENVSKNSDVANVFFKTYLVSLLNDILYILTDSFHKSGFALECDILRMMFQVVENGVVKIPLFDPQQANFPSNSEYVKEIVVTFLSASPNVSRPQIQAFVTRLFNLANINNNDFKSATRDFLITLKEWKSHENADLYSDEKNIEKALALKKQSMIPGMVRPNDVNLEMNDL
What is the function of this protein?
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES).
What are the official names of this protein?
Exportin-1, Exp1.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Shuttles between the nucleus and the cytoplasm.
Protein: SAFA_ECOL6
Sequence: MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: ORF5_BFDV
Sequence: MGGAYITSRYWLVPAHVTSRLRLTSFTGHRGVARVDGPMSSLGLNIIKCAVNGGMDMTGKMSSSWTIFMGGYLIARCSASATVIHIKCQSRALLWSLPARG
What are the official names of this protein?
Uncharacterized protein ORF5.
Protein: YCAD_SALTY
Sequence: MSTYTRPVMLLLCGLLLLTLAIAVLNTLVPLWLAQANLPTWQVGMVSSSYFTGNLVGTLFTGYLIKRIGFNRSYYLASLIFAAGCVGLGVMVGFWSWMSWRFIAGIGCAMIWVVVESALMCSGTSHNRGRLLAAYMMVYYMGTFLGQLLVSKVSGELLHVLPWVTGMILAGILPLLFTRIVNQQTQARHSSSISAMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLKHQGMANASIGFWMAVLVSAGILGQWPMGRLADKFGRLLVLRVQVFVVILGSIAMLTQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFAAMLMQNYSDNLLFIMIASVSFIYLLMLLRNAGQTPNPVAHI
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSRR_ECO57
Sequence: MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
What is the function of this protein?
Regulates transcription of many different genes.  In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription.  In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity).
What are the official names of this protein?
Transcriptional regulator LsrR.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_DESVV
Sequence: MGQKVHPFGFRLGYNKNWQSRWYSKKEYPAFVFEDHNIRKFVKKTLYHAGLAKIEIERAGGKVRLILSTARPGIVIGRKGVEIEKLRADLRKKFKREFAIEVNEIRRPEVESQLVAENIALQLERRVAFRRAMKRTVSMARKFGAEGIKVTCSGRLAGAEIARTEWYRDGRVPLQTLRADIDFGFAEARTTYGVIGVKVWIFKGELLDNEVA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DCYD_ECO7I
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVIPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNTQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: Y4BN_SINFN
Sequence: MPSQMREAITRLNEEFGCRIFVISLGDKKRVFDGGKVGTWAATLDELARERNVVIIVSAGNRGPRAGSRVEQGVTEYPDYLLEANNRLLEPAGAMNVITVGSIAQGDGLDADMAGDVRVRPITRANEPSPFSRVGPGLGGGTKPDLVDVGGTLIFDPVVARLRGGEDRPSAGVLTLNHNYLNRLFTAGSGTSYSAPRVGFSAGQILARFPGASANLVRALLINSAEVPQQASERLQILGSEAVRSVCGHGLIDLERAGFSDDARVTLYTEDELPLDHFAVYRIPIPEVFQEGNTERTIRVTLAYDPPVRHTRNDYAGVGMSFRLVRGCEPNFIFEHYRKRAEVEGPFPEMENRFNCKLEPGPKVREKSSVQRASITFKRGIEQYGDSYYLVVRCESGWATHVDRQPFAVVVELLQKAEVRLYERLRQRVRA
What are the official names of this protein?
Uncharacterized protein y4bN.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: GCS2_CORGB
Sequence: MGIEFKRSPRPTLGVEWEIALVDPETRDLAPRAAEILEIVAKNHPEVHLEREFLQNTVELVTGVCDTVPEAVAELSHDLDALKEAADSLGLRLWTSGSHPFSDFRENPVSEKGSYDEIIARTQYWGNQMLIWGIHVHVGISHEDRVWPIINALLTNYPHLLALSASSPAWDGLDTGYASNRTMLYQQLPTAGLPYQFQSWDEWCSYMADQDKSGVINHTGSMHFDIRPASKWGTIEVRVADSTSNLRELSAIVALTHCLVVHYDRMIDAGEELPSLQQWHVSENKWRAARYGLDAEIIISRDTDEAMVQDELRRLVAQLMPLANELGCARELELVLEILERGGGYERQRRVFKETGSWKAAVDLACDELNDLKALD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CNBL2_ARATH
Sequence: MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner.  Binds four calcium ions per subunit.  Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement.  Mediates the inactivation of the proton pump AHA2 by CIPK11.  Probably involved in regulating signaling responses to abscisic acid.
What are the official names of this protein?
Calcineurin B-like protein 2, SOS3-like calcium-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor. Note=The tonoplast localization is S-acylation dependent and is abolished by 2- bromopalmitate (2-BP) treatment.
Protein: DHYS_THEGJ
Sequence: MTEPKDIVLKESEEVEGTPIEGPWLDEVSSLEEVLDYYERIGFQATHLGKAIEIWKKVEEKRARGEEVRVFLGYTSNIISSGLREIIAWLVKEGKVDVIVTTAGGIEEDFIKALKPFILGDWNVNDALMREKGINRIGNIFVPNDRYIEFEKYMIPFFERVLEIEKERGKPLTASEFIYEMGRFMDEKLGKEKEKSVIYWAYKRNVPIFCPAITDGSIGDMLYFFKEERGDRELIIDIANDIVKLNNLAVTAKETASIILGGSLPKHAIINANLFRGGTDYAIYVTTAIPWDGSLSGAPPSEGVSWGKIRAKADYVEIWADATLVFPLLVWKVMRS
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: COAX_BACC4
Sequence: MIFVLDVGNTNAVLGVFEEGELRQHWRMETDRHKTEDEYGMLVKQLLEHEGLSFEDVKGIIVSSVVPPIMFALERMCEKYFKIKPLVVGPGIKTGLNIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITKPSSVVGKNTVSAMQSGILYGYVGQVEGIVKRMKEEARQEPKVIATGGLAKLISEESNVIDIVDPFLTLKGLYMLYERNANLQHEKGE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y795_TOLAT
Sequence: MPSFDIVSEVAMNEVQNAVENANREIQTRFDFRGVDASFELNKEEIKMGADADFQLKQMIEILRDKIVKRGMDTSCLDVGDVEHSGKRYFQVVKLKQGIETDVAKKLIKIIKDAKIKVQTAIQGDEIRVTGKKRDDLQEAMALVRQAELGQAFQFTNFRD
What are the official names of this protein?
UPF0234 protein Tola_0795.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CYSH_GEOSW
Sequence: MLTYQTWEAEEKPSFPHDNETKGALDVLTWAFRQYKDDIVYACSFGVEGIVLIDLISQVKPDAEIVFLDTGLHFRETYKTIEKVKEKYPSLRIVMKKPSLSLEEQAQQLGDELWKHNPNKCCELRKVIPLREALTGITAWISGLRREQSPTRSHVEYINKDDKFKSIKICPLIHWTWKDVWNYVYKRRLPYNVLHDRGYPSIGCEPCTSPALDPNDLRSGRWVGHGKTECGLHIS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPYA_FUSV7
Sequence: MRLSTSALVLGAASSAVAFDQKVLGDLKKPAIDLDLSSWLNFGEEITAEAKAVWEEVSMLAPDAVEAFKKQVIGTKPKKANRRPDNHWDHVVKGADVQSIWVDKNNEKHRKVGGRLDNYNLRAKKVDPSKLGVDKVKQYSGYLDDEEQDKHLFYWFFESRNDPENDPVVLWLNGGPGCSSLTGLFLELGPASINKKIEIVNNPWSWNNNASVIFLDQPVNVGYSYSGGSVSNTVAAGKDIYALLTLFFHQFPEYAKQDFHIAGESYAGHYIPVFANEILSHEDRNINLKSVLIGNGLTDGYTQYEYYRPMACGEGGYPSVLSESECQSMDNALPRCQSLIKGCYESGSAWSCVPASIYCNNAMMGPYQRTGRNVYDIRGNCEDSSNLCYSGLGYIAEYLNRQDVQDALGAEVSSYDSCNMDINRNFLFAGDWMQPYHQVVPNLLEKIPVLIYAGDADFICNWLGNQAWTNKLEWPGHKDFKNADIKNLKVEGKEYGKIKTSGNFTFMQIYGAGHMVPMDQPEASSDFFNRWLGGEWF
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RS7_METM6
Sequence: MEIKLFGKWDSETVTVKDPSLKSYVSVTPVLVPHTAGRNSKKSFDKSKMNIVERLANKLMANQNNTGKKHETLAIVEEALTIIENRTKENPVQVLVDALENSGPREETTRISYGGIAFLQSVDVSPSRRLDTAFRNIALGASQSAHKNKKTVAQCLADEIIFASKADMQKSFAVRKKEEKERVAQSAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RPOB_SHEPA
Sequence: MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMDLVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQDYIDPDTGEVLVSANADISLEDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSKVGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVVTDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHKGDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAKRGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKDLTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAEELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNRITEMLEEQRELAELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQMLELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDTK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AOXA_RABIT
Sequence: MEPAPELLFYVNGRKVVEKQVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNRVTKKIRHYPVNACLTPICSLYGAAVTTVEGIGSTTTRLHPVQERIAKFHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLADALGGNLCRCTGYRPIIEAYKTFCKTSDCCQNKENGFCCLDQGINGLPEVEEENQTRPNLFSEEEYLPLDPTQELIFPPELMTMAEKQPQRTRVFSGERMMWISPVTLKALLEAKSTYPQAPVVMGNTSVGPGVKFKGIFHPVIISPDSIEELNVVSHTHSGLTLGAGLSLAQVKDILADVVQKVPEENAQTYRALLKHLGTLAGSQIRNMASLGGHIISRHLDSDLNPLLAVGNCTLNVLSKEGERQIPLDEQFLSRCPEADLKPQEILASVHIPYSRKWEFVLAFRQAQRKQNALAIVNSGMRVFFGEGDGIIRELAISYGGVGPTIICAKNSCQKLIGRSWNEEMLDTACRLILDEVSLPGSAPGGKVEFKRTLIISFLFKFYLEVSQILKRMAPGLSPHLADKYESALQDLHARYSWSTLKDQDVDARQLSQDPIGHPVMHLSGVKHATGEAIYLDDMPAVDQELFMAFVTSPRAHAKIVSTDLLEALSLPGVVDIVTAEHLQDGNTFYTEKLLAADEVLCVGQLVCAVIAESEVQAKQAAKQVKIVYEDLEPVILSIEEAIEQKSFFEPERKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSVLVVPKGEDQEMDVYASTQFPKYIQDMVAAVLKLPVNKVMCHVKRVGGAFGGKVFKASIMAAIAAFAANKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRIVALDVEHYSNGGCSLDESLLVIEMGLLKMENAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAGLITECCITEVAAKCGLSPEKVRAINFYKEIDQTPYKQEINAKNLTQCWNECLAKSSYFQRKVAVEKFNAENYWKQRGLAIIPFKYPRGLGSVAYGQAAALVHVYLDGSVLVTHGGIEMGQGVHTKMIQVVSRELKMPMSNVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIINKNPQGTWKEWAQAAFDKSISLSATGYFRGYDSNIDWDKGEGHPFEYFVYGAACSEVEIDCLTGDHKTIRTDIVMDVGYSINPALDIGQVEGAFIQGMGLYTIEELHYSPQGILYSRGPNQYKIPAICDIPAELNVTFLPPSEKSNTLYSSKGLGESGVFMGCSVFFAIREAVCAARQARGLSAPWKLSSPLTPEKIRMACEDKFTKMIPRDKPGSYVPWNVPV
What is the function of this protein?
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin.  Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents.  Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent.  Is probably involved in the regulation of reactive oxygen species homeostasis.  May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen.  May also catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor.  May play a role in adipogenesis.  Cannot use hypoxanthine and all-trans-retinol as substrate.
What are the official names of this protein?
Aldehyde oxidase 1, Azaheterocycle hydroxylase 1, Retinal oxidase, Retinoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_ERWT9
Sequence: MPKHPLTIALVAGETSGDILGAGLIRALKEKHPDARFVGVAGPLMQSEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRRDLTRRFTALKPDVFVGIDAPDFNITLEGRLKQQGIRTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDRFNVPCRFIGHTMADAMPIVPDKQAARRELGIAPQALCLALLPGSRSAEVEMLSADFLKTAMLLREKYPQLEIVVPLVNPRRRAQFEAIKAEVAADLPMHLLDGKGREAMLASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVPELLQDECQPQRLAAALEPLLAQGETRDTLLATFAELHHQIRWNADEQAAAAVLELCR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: GLGX_ECO8A
Sequence: MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: GBLPB_ORYSJ
Sequence: MAGQESLTLAGVLRGHNDMVTAIAAPIDNSPFIVSSSRDKSLLVWDITNPSTAVATDPEAAPPEYGVSYRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGRTTRRFVGHTKDVLSVAFSVDNRQIVSAARDNTIKLWNTLGECKYTIGGDHGAGEGHTGWVSCVRFSPNPMAPTIVSGSWDRSVKVWNLTNCKLRTKLEGHNGYVNAVAVSPDGSLCASGGKDGTTLLWDLTEGKMLYKLDAGAIIHSLCFSPNRYWLCAATEDSVKIWDLESKLVMQDLKPEVQAFKSQMLYCTSLSWSADGSTLFAGYTDGTIRVWKVSGFGGYAI
What is the function of this protein?
Component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein B, GPB-LR, Receptor for activated C kinase 1B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: TIM8_ASHGO
Sequence: MSGISPTELQNLDEPSKKEIMGFLETENSKQKVQMSIHQFTNLCFKNCIHSVQSADLSAQENQCLKDCVNRFLDTNIRIVKGLQSIQ
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM8.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: YAII_ECO7I
Sequence: MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRCRG
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.