PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_STRGC
Sequence: MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDTGHDVIIGVRPGKSFDKAKEDGFDTYTVAEAAKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGNAKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FLJK_CAUVC
Sequence: MALNSINTNAGAMIALQNLNGTNSELTTVQQRINTGKKIASAKDNGAIWATAKNQSATAASMNAVKDSLQRGQSTIDVALAAGDTITDLLGKMKEKALAASDTSLNTASFNALKSDFDSLRDQIEKAATNAKFNGVSIADGSTTKLTFLANSDGSGFTVNAKTISLAGIGLTTTSTFTTAAAAKTMIGTIDTALQTATNKLASLGTSSVGLDTHLTFVGKLQDSLDAGVGNLVDADLAKESAKLQSLQTKQQLGVQALSIANQSSSSILSLFR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin FljK, 25 kDa flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RBSD_BACC7
Sequence: MKKHGVLNSEIAAVLASLGHTDTIVIADCGLPIPDGVKRIDLAVEIGKPSFLDVLQVVADDMAIEKVTLAEEVINNNAEVNKEIELKLIEPAFEYVSHEQFKEHTKKAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_BORBU
Sequence: MKVIFMKADLNLIKTLHPLEIKVIVNNEEEDDISASIIIEKLGFNEGQANKTIEWLNSKGIIEEIYRKLNVFYKATERGLGALRDGFVEEKIINLVSQKAVLASNLALELDIDVKEVRKAFGNLLKEGILSLDLDKQIIINCLDGTETNYQKVRVLLERAKNSDLLRESLTTEELLLISNFAKKKGADSVFFKIIEKLDLKFRLSSFGLEVKNFLMKSKLTGDELTKLTPEILKNKTYENKKFRAYNIHIPSAKTFIGRANSYLDYISKIKDKLVGLGFQEFDGPLVETEFFNNDALFMPQFHPSRDIKDVYYISDPSMQESLPEPYFSNVKLAHETGYATGSRGWRYSFSEDLSKRLVLRTHGTVLSAKQLINAKNPSRYFGVIRCFRYDQVDATHGVDFYQTEGIVIEDGVSIKTLLGLLEIFAKELAGATEIKYVPAYFPFTEPSIEIHVKHPVLGWFELGGSGIFRPEVTKPLGIDLPVIAWGIGIDRMALMHLGLNDLRDLFTYDIGDVILRRGKIDAKVRNL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP3_RHIEC
Sequence: MNDEEQDDKTKELPLGKETEANLFKSRSIFIYGPINQELAQKVCSQLVALAAASDEDIRIYVNSPGGHVESGDSIHDMVKFIKPKVWMIGTGWVASAGALIYVAAPRERRLCLPNTRFLLHQPSGGTRGMASDIEIQAREIIKMNERLNKIMAEATGQPLEKIAKDTDRDYWLSAEEAKDYGLVSRIVTSQADI
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ANAD2
Sequence: MPGTSELITVAVPKGRLLQESSALFERALGVSPRKLLEGTRKLAADAPEAGLRFISIRAGDVASYVEHGAAEVGIVGLDVLREEPRDLYEPLDLGIGRCTVIVARPKGARPLPRGVAPRVATKYLSLAARHFAAKGVPAEIIPLHGSIEVAPSLGLADTIVDITETGETLRANGLVIEEKVLEVSARLVVNRVALKLHPERLRRLIEALRAAVAEAGAEAR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAU40_ARATH
Sequence: MKPLIRRLSRIADSSSCNRNRSGDIHHPTSTYSSSVFLVKRATVASSVPSGHVPVNVGEDKERFVVSAELLNHPVFVGLLNRSAQEYGYTQKGVLHIPCNVFVFEQVVESLRSGIADDTSELIASLSGEDVSTE
What is the function of this protein?
Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e. g.  AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (PubMed:24858935).  Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport (By similarity).
What are the official names of this protein?
Auxin-responsive protein SAUR40, Protein SMALL AUXIN UP RNA 40.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
Protein: RIMM_YERE8
Sequence: MSKQLNPVVPEQPIVLGKMGSTYGIRGWLRVFSSTENAESIFDYQPWFIQQGGKWQHVELEDWKRHSQDLIIKVKGVDDRDAANLLTNCEIVVDSKQLPELEEDDYYWKDLMGCQVVTTAGYELGKIIDMMETGSNDVMVVKANLKDAFGMKERLVPFLHGQVIKNVDLTAQRVEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA2_HELMI
Sequence: MQRPIIAIPMGDPAGVGPEIVVKALANEEMYRIARPLVIGDAGVLRQAMAFCGLELAVHTVTEPAMGKFEPGVIDLIDLANVELKQLKMGAVQAMAGNAAYECIEKSVSLAMAGQVDAIATTPINKEALKAAGIPHIGHTEILGHLSGANDPLTMFQVFELRVFFLSRHVSLRKACDMVTTERALDYLVRCTEALRRLGVDSPKFAVAGLNPHSGEHGLFGDEEDEQIAPAIAAARERGINVVGPVPADSVFYFGLKGAYDAILSLYHDQGHIATKMVDFERTVAVTNGLPFLRTSVDHGTAFDIAGSGKASSVSMEEAIKLAVRYAPSFRRY
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-erythronate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).  Can also use D-threonate 4-phosphate as substrate.
What are the official names of this protein?
D-erythronate 4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family. PdxA2 subfamily.
Protein: RCA_ARAHY
Sequence: GLAYDISDDQQDITRGMVDSLFQAPMNDGTHYAVMSSYEYISQGLRVPLILGIWGGKMGINPIMMSAGELESGNAGEPAKMCCLFINDLDAGAGRVPIIVTGNDFSTLYAPLIRIGVCTGIFRLVDTFPGQSIDFFGALR
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, RA, RuBisCO activase.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PGM1_DICDI
Sequence: MFKQTFKVNIIPTQPFEGQKPGTSGLRKKVTEVMKTNYLGNFVQSIFNALPEDKLKGSTIVVGGDGRYYNNDAIQLIFQIAAANGVGKILVGRYGLLSTPAISAIVRARSALGAIILTASHNPGGPNGDFGIKYNMSNGGPAPESITNAIYKHTTSITQIKTTRNVSVDNLGLLKTYEWNDGEFVIEVIDSADDYVSLLKTIFDFDGIRKFVKNHPNFTFNFDAMSGVTGAYGKRIFTDELGIPESCLINCNPSQDFNGGHPDPNLTYAPLLVKKMNNGEFDMGCASDGDGDRNMILGKRFFLNPSDSVAVIASNYKAIPYFNKGGLKGLARSMPTSAALERVATDLKVPFFEVPTGWKFFGNLMDAGTLSICGEESFGTGSDHIREKDGIWAIICWLQILTHHNQSTNDKNFVSIEEIVKQHWAKYGRNYYSRYDYEEIDTAPAEAMMKHVSQQIESKQLIGKKFTGISDSLEYEIASCDDFEYKDPIDSSVSSHQGLRIIFTDGSRIIYRLSGTGSTGATVRVYFDKYETQPTQLNNDVQTHLKSLIHIALVEISKLNHYTGRNEPNVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase-1, PGM 1, Glucose phosphomutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPC2_DICDI
Sequence: MNALRGLLNKYTGNQIVFSNKYATTFFEKFPKLAFLNNVTNLAPMMKWSLSIVPITQILSGTKLPENIDVYQASSLCATGSIWTYYATLISPQNTGTRMLAACNAAMAACHGYNIYRRTKWEKSQIIPIENKN
What is the function of this protein?
May mediate the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Probable mitochondrial pyruvate carrier 2, MPC2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MGP3_MYCPN
Sequence: MKSKLKLKRYLLFLPLLPLGTLSLANTYLLQDHNTLTPYTPFTTPLNGGLDVVRAAHLHPSYELVDWKRVGDTKLVALVRSALVRVKFQDTTSSDQSNTNQNALSFDTQESQKALNGSQSGSSDTSGSNSQDFASYVLIFKAAPRATWVFERKIKLALPYVKQESQGSGDQGSNGKGSLYKTLQDLLVEQPVTPYTPNAGLARVNGVAQDTVHFGSGQESSWNSQRSQKGLKNNPGPKAVTGFKLDKGRAYRKLNESWPVYEPLDSTKEGKGKDESSWKNSEKTTAENDAPLVGMVGSGAAGSASSLQGNGSNSSGLKSLLRSAPVSVPPSSTSNQTLSLSNPAPVGPQAVVSQPAGGATAAVSVNRTASDTATFSKYLNTAQALHQMGVIVPGLEKWGGNNGTGVVASRQDATSTNLPHAAGASQTGLGTGSPREPALTATSQRAVTVVAGPLRAGNSSETDALPNVITQLYHTSTAQLAYLNGQIVVMGSDRVPSLWYWVVGEDQESGKATWWAKTELNWGTDKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAYLIAGLDVVADHLVFAAFKAGAVGYDMTTDSSASTYNQALAWSTTAGLDSDGGYKALVENTAGLNGPINGLFTLLDTFAYVTPVSGMKGGSQNNEEVQTTYPVKSDQKATAKIASLINASPLNSYGDDGVTVFDALGLNFNFKLNEERLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTNTASHYLPVPYYYSANFPEAGNRRRAEQRNGVKISTLESQATDGFANSLLNFGTGLKAGVDPAPVARGHKPNYSAVLLVRGGVVRLNFNPDTDKLLDSTDKNSEPISFSYTPFGSAESAVDLTTLKDVTYIAESGLWFYTFDNGEKPTYDGKQQQVKNRKGYAVITVSRTGIEFNEDANTTTLSQAPAALAVQNGIASSQDDLTGILPLSDEFSAVITKDQTWTGKVDIYKNTNGLFEKDDQLSENVKRRDNGLVPIYNEGIVDIWGRVDFAANSVLQARNLTDKTVDEVINNPDILQSFFKFTPAFDNQRAMLVGEKTSDTTLTVKPKIEYLDGNFYGEDSKIAGIPLNIDFPSRIFAGFAALPSWVIPVSVGSSVGILLILLILGLGIGIPMYKVRKLQDSSFVDVFKKVDTLTTAVGSVYKKIITQTSVIKKAPSALKAANNAAPKAPVKPAAPTAPRPPVQPPKKA
What are the official names of this protein?
Mgp-operon protein 3, Mgp3, ORF-3 protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRAY5_ECOLX
Sequence: MSRGRTRAAPGNKVLLILDETTNQKLLAARDRSGRTKTNEVFIRLKDHLNRFPDFYNSSLVKEEAEGIDDI
What is the function of this protein?
Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell.  It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations.  Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site.  Relaxosome formation requires binding of IHF and TraY to the oriT region, which then facilitates binding of TraI.  Also positively regulates tra gene expression (By similarity).
What are the official names of this protein?
Relaxosome protein TraY.
What is the protein family that this protein belongs to?
Belongs to the TraY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2N3_BUNFA
Sequence: NLFQFKNMIQCAGTRSWTDYVSYGCYCGKGGSGTPVDQLDRCCKVHDDCYGDAEKIPKCKPYYKTYSYDCSEGKLTCKADNDECAAFICNCDRVAAICFAGAPYNDNNFMIDSKTRCNDI
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Neutral phospholipase A2 3, svPLA2, Kbf III, Kbf-3, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NLP7_CAEEL
Sequence: MYIKAALLIVVLFGVASQITSALYLKQADFDDPRMFTSSFGKRSAIESEPQAYPKSYRAIRIQRRSMDDLDDPRLMTMSFGKRMILPSLADLHRYTMYDKRGSDIDDPRYFLFSNRLTCRC
What is the function of this protein?
May regulate lifespan in response to food availability and oxidative stress.
What are the official names of this protein?
Neuropeptide-like protein 7.
Protein: ACPT_ECOLI
Sequence: MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHTLSPLPEIIYGEQGKPAFAPEMPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWRWLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSSLSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN
What is the function of this protein?
May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis in E. coli.  The native apo-protein substrate is unknown.  Is able to functionally replace AcpS in vivo but only when expressed at high levels.
What are the official names of this protein?
4'-phosphopantetheinyl transferase AcpT.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
Protein: AIF1L_HUMAN
Sequence: MSGELSNRFQGGKAFGLLKARQERRLAEINREFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKANESSPKPVGPPPERDIASLP
What is the function of this protein?
Actin-binding protein that promotes actin bundling.  May neither bind calcium nor depend on calcium for function.
What are the official names of this protein?
Allograft inflammatory factor 1-like, Ionized calcium-binding adapter molecule 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with F-actin. Partially relocates to membrane ruffles in response to invading bacteria.
Protein: S35F4_HUMAN
Sequence: MDELLLDLFHKLTSGRQLAAGNGLCGISHKEQEVWKPGHNILVKMRKEDKSLVWLIHSTLARYTQVTNFLGTSRSSVTRCKPGANCPSSHSGISRQLSPLSVTEDSSAPILELQNQGSSGVCGHRVERQNRSADDGTQTHSENSSQENRIKARCLSCTSMVLKGIWGLLIILSVSSSWVGTTQIVKITYKNFYCPFFMTWFSTNWNIMFFPVYYSGHLATAQEKQSPMKKFRECSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLALKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANFGEAAHFVSTLGFFNLIFISFTPVILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVVLTYPILISIGTVLSVPGNAAVDLLKQEVIFNVVRLAATIIICIGFLLMLLPEEWDEITLRFINSLKEKKSEEHVDDVTDPSIHLRGRGRANGTVSIPLA
What is the function of this protein?
Putative solute transporter.
What are the official names of this protein?
Solute carrier family 35 member F4.
What is the protein family that this protein belongs to?
Belongs to the SLC35F solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KCNK3_MOUSE
Sequence: MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPEMIERQRLELRQLELRARYNLSEGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTFVRYLLHRAKRGLGMRHAEVSMANMVLIGFVSCISTLCIGAAAFSYYERWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTHNGQAVGLGGLSCLSGSLGDGVRPRDPVTCAAAAGGVGVGVGGSGFRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEHSHSSPGGGGRYSDTPSHPCLCSGTQRSAISSVSTGLHSLAAFRGLMKRRSSV
What is the function of this protein?
pH-dependent, voltage-insensitive, background potassium channel protein.  Rectification direction results from potassium ion concentration on either side of the membrane.  Acts as an outward rectifier when external potassium concentration is low.  When external potassium concentration is high, current is inward.
What are the official names of this protein?
Potassium channel subfamily K member 3, Acid-sensitive potassium channel protein TASK-1, Cardiac two pore background K(+) channel, TWIK-related acid-sensitive K(+) channel 1, Two pore potassium channel KT3.1, Two pore K(+) channel KT3.1, cTBAK-1.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NPD_CALMQ
Sequence: MGNGECLEGGRKAAVILTSSRHAIAFTGAGISTESGIPDFRGPQGLWRRFDPALASIDYLNTDPKGFWEFYIERFRVLNNARPNKAHLALAELEKLGIIKYVITQNIDNLHQSAGSINVIELHGNYTTVYCMRCKTQYPFTLALRKYEEGENPPRCPKCGGILRPNVVLFGEPVNEINRALEIAALSDVALVVGSSLTVYPAAYVPLVVKEHGGRLIIINLEPTDYDDYADVVLHCSASEALDLVLNEVKGIMAAGN
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.  Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_LACLS
Sequence: MFDQLESIVGRYEELGELLSDPEVVSDTKRFMELSREEADLRDKVATYNEYKKVLETISDSEEMLGEGGLDDEMKEMLKEELSSAKSQKEVLEEEIKILLLPKDPNDGKNIILEIRGAAGGDEAALFAGDLLNMYQHFSESQGWKFEIMEANITGIGGYKEVSALISGPSVYSKLKYESGAHRVQRVPVTETQGRVHTSTATVLVMPEVEEFEMTIEQKDLRVDIYHASGAGGQNVNKVATAVRMVHLPTGIKVEMQEERTQQKNRDKAIKLLNTKVFDYYQQIELDKQNAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDSILSGKMDEVIDALIVYDQTKKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_PEDPA
Sequence: MSNNVIEKVTELVQPITDRHNFELVEVEFVKEGQGWFLRVYIDKVGGINIEECAMVSDELSEILDAQDPDPIPQAYFLEVSSPGAERPLKTKEDLTRSIGEYIHISLYASINKQKVFEGYLKSFENDEIVLDYLDKTRHKELKVTYDQVAFARLAIKI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLIG2_MOUSE
Sequence: MDSDASLVSSRPSSPEPDDLFLPARSKGGSSSGFTGGTVSSSTPSDCPPELSSELRGAMGASGAHPGDKLGGGGFKSSSSSTSSSTSSAATSSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPTATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLSSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGGSGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGTLPRLTSDAK
What is the function of this protein?
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain (PubMed:11955448, PubMed:12121626, PubMed:16908628).  Functions together with ZNF488 to promote oligodendrocyte differentiation (PubMed:16908628).  Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube (PubMed:11955448, PubMed:12121626).  Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (PubMed:11955448, PubMed:12121626).
What are the official names of this protein?
Oligodendrocyte transcription factor 2, Oligo2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2.
Protein: RL17_ANAD2
Sequence: MKHRVVGRRLDRTTEHRTAMFKNMVTSLFRHERIVTTTPKAKELKRFADKVITQAKRGTPHARRLAHRDVRDVEVLNKLFDTLAERFKARPGGYTRIVRVGRRAGDNAEMSVIELVDRAPAAAPEAEEKGEKKATKAPKAEKAPKAEKAPKAEKKPAKKAAKAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PLSY_DINSH
Sequence: MPELTTAPGLLALVGLAAYLLGAIPFGLLIAKLFGLGNLREIGSGNIGATNVLRTGSKPAAAATLILDAGKGAFAVILARVLVGEDAAQIAGAAAFLGHCFPVYLKFNGGKGVATFFGTVIALSWPLGLAAGAIWLATAYTFRISSLSALMAALMTPIFAWGFGQRELVVLSLFLGFLIWIRHRENIIRLLSGTEPRIGAKKR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCR4_PHANO
Sequence: MSNAQPHFAPSHLQNGTPNSVHSGVNRPTTEHWAEQRTRSADSTKRRTRKSATGQQHSEPRTARTTSRGQYVDFGGQNLKVITPTLFINYSFLTKLYLNANKLTYLHQAIGQLRNLTHLDLSLNNLHSLPPEIGMLVNLKQLLVFDNQLTDLPEELGSLYQLELLGIEGNPIPDDIKQIMMEQGTVELIKHFRETAAGPEAPPERDWIVLDEITDPAQETVTALSYNILCDKYCTQSQYGYTPSSALAWETRRELILGELKQRNADIVCLQEIDQDSFNEYFREKLAHYDYKGVFWPKSRARTMAEREAKLVDGCAIFYKNSKYVLLDKQLIDFANTAINRPDMKGEHDIFNRVMPRDDIGVVAFLENRATGSRFIVGNVHVFWNPAFTDVKLVQVAILMEGISKFATKWSKFPPCKDKVVYRFTNGDDEDGKEADTTQEPGPSKEYGAGADIPVILCGDFNSMPSSGVYDLITQGTIAHSHQDLGSRKYGNFTRDGISHPFSLKSSYSAIGEMTFTNYVPHFQGVLDYIWYSTNTLQVVGLLGDIDKEYLRRVPGFPNYHFPSDHVALYAQYIVKGRKEKKVSEVDFGPSRDRERR
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RCRO_BPP22
Sequence: MYKKDVIDHFGTQRAVAKALGISDAAVSQWKEVIPEKDAYRLEIVTAGALKYQENAYRQAA
What is the function of this protein?
Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth.  It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
What are the official names of this protein?
Regulatory protein cro, Antirepressor.