PharMolix/UniProtQA huggingface dataset:
Protein: DPS_YERPB
Sequence: MSTAKLVKTKPSELLYTRNDVEEHVKVATIKRLNQMVIQFIDLSLITKQAHWNMRGANFVAVHEMLDGFRTALTDHLDTFAERAVQLGGVALGTAQVINDKTPLKSYPTNIHSVQEHLKALAERYAIVANDIRKAITEVEDENSADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BRUA1
Sequence: MNKPKNSPARKMIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQANIAESYASFEDGEFWLINSYIPEYTQGNRFNHEPRRLRKLLVSRREMSRLFNSVSREGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLLRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HRH2_CANLF
Sequence: MISNGTGSSFCLDSPPCRITVSVVLTVLILITIAGNVVVCLAVGLNRRLRSLTNCFIVSLAITDLLLGLLVLPFSAFYQLSCRWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPVRVAVSLVLIWVISITLSFLSIHLGWNSRNETSSFNHTIPKCKVQVNLVYGLVDGLVTFYLPLLVMCITYYRIFKIARDQAKRIHHMGSWKAATIGEHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAINEAFEAVVLWLGYANSALNPILYATLNRDFRTAYQQLFRCRPASHNAQETSLRSNSSQLARNQSREPMRQEEKPLKLQVWSGTEVTAPRGATDR
What is the function of this protein?
The H2 subclass of histamine receptors mediates gastric acid secretion.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Histamine H2 receptor, H2R, HH2R, Gastric receptor I.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SLYX_ECO24
Sequence: MQDLSLETRLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: ESS2_MOUSE
Sequence: MGTPGTSAGALFLSSASAPSRKRAAGEAGEAGVARSRQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPPYVTPATFETPEVHPGSAVLGNKPRPQGRDLDDGEAGEEEEKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLPARRKASDFF
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Splicing factor ESS-2 homolog, ES2 protein, Expressed sequence 2 embryonic lethal.
What is the protein family that this protein belongs to?
Belongs to the ESS2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4_METS5
Sequence: MGDPRKSRRKWEGPGMPWLSQALKSEQKIMGDYGLRNKKEIWLARTIVTGYRHMARSLLALPPAERAVREKQLLGKLYKLGLLKSEQSTIDDILGLEEESLLERRLQTIVHRKGLARTIYQARQLIVHGHIAVGGRKITSPGYIVKRDEEDSIDFYPTSPFKNNPPTAGQGEVNVEQKGN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RF3_SYMTH
Sequence: MDSLADQIRRRRTFAIISHPDAGKTTLTEKLLLYGGAIRLAGAVKGRKAARAATSDWMEIEKQRGISVTTSVMQFEYGGCMVNILDTPGHQDFSEDTYRTLEAADSAVMLIDAAKGVEPQTIKLFQVCRMRGIPIFTFVNKLDREGKDPFALMQEIEDVLGMRTCPMNWPVGMGSTFKGVYDRQKGHVELFDNRDHGQTKARVETTGVDDPALSAVLGEDLHRRLVEEIELLDVAGDPWDFDRFRRGDLSPLFWGSALTNFGVQSFLEYFLKLAPAPAPRLAGDRLVDPEEPRFSAFVFKIQANMNPAHRDRIAFMRIVSGRFERGMDVQHVRLGKKVRLSQPQQFMAQDRQIVEEAYAGDIIGVFDPGIFRIGDTLCTGEPVAFEGIPSFSPEHFARVRFKDAMKSKHFRKGLEELTEEGAIQVFYATQPGHPDPILGAVGELQFEVFQHRMRHEYGVEVILDRLPYEVARWVEGEGYQPRRFWGTDHMAVTDRDGRNVLLFRNEWTMRYVVEQNPGLIFRATAQAR
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_METM7
Sequence: MARMKARSAKGKRVAKDTWKSKVWYDIYTPQSFGGDVIGQTPANDPATLIGRISEISLRDLTNEHSKHMTRMYFKVDGVSGNNATSQFVGHDTTREYLKSQVRRRRSKINAIVDVRTKDGFKLRVKALVLTAVRARDHHKTEIRVKMEQIIKDMAKETAFAEFVHAMLMGGLGSKIYGDCKKMFPLKRVEIFKSEVLEFGKVVEAPVEEAAVEAPVEEAAETQE
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: Y967_MYCBO
Sequence: MGRSATIAMVPKRRDAMNRHSGPILSSGFIASSSNSCPANSLRMPSALAAETLSFDDRAVRRSTHHPGGGYPQKHAINLQSGLCPAYANASR
What are the official names of this protein?
Uncharacterized protein Mb0967.
Protein: ACPS_SYNC1
Sequence: MPYLSGLGNDLVRIQRFRRFLEAGKTAILERLFTEEERSFCLAKKDPAPHFAVRFAAKEAFLKALGTGLRYGIRWQDMAVVRNPEGKPDLVLDGEAARLFEDRGHVRLLLSCSHDGDYAFATVVFEGN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE1_HPV12
Sequence: MADSKGSTSKEGLSDWCILEAECSDLENDFEQLFEQDTDSDVSDLLDNGELEQGNSLELFHQQECEQSEEQLQILKRKYLSPKAVAQLSPRLESISLSPQQKSKRRLFAEQDSGLELSLNNEAEDVSPEVEVPAIDSRPVDEGGSGAIDIDYLSLLRSSNIKATLMAKFKESFGVGFNELTRQFKSYKTCCNDWVLAVYAVHDDLFESSKQLLQQHCDYIWVRGIGAMTLYLLCFKAGKNRGTVHKLMTSMLNVQEQQILSEPPKLRNTAAALFWYKGGMGSGAFTHGTYPDWIAHQTILGHQNAEASTFDFSAMVQWAFDNNYLEEPDIAYQYAKLAPEDSNAVAWLAHNQQAKFVRECAAMVRFYKKGQMKEMSMSEWIHTKINEVEGEGHWSDIVKFLRYQDVNFITFLAAFKNFLHAVPKHNCILIYGPPNSGKSSFAMSLIKVLKGRVLSFVNSKSQFWLQPLGESKIALLDDVTDPCWVYIDTYLRNGLDGHFVSLDCKYKAPVQIKFPPLLLTSNINVHGETNYRYLHSRIKGFEFPHPFPMKPDNTPQFQLTDQSWKSFFERLWTQLDLSDQEEEGQHGESQRAFQCSARSANEHI
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NLP6_ARATH
Sequence: MELDDLDLSGSWPLDQITFASNFKSPVIFSSSEQPFSPLWSFSETSGDVGGELYSAAVAPTRFTDYSVLLASSESETTTKENNQVPSPSWGIMPLENPDSYCAIKAKMTQALRYFKESTGQQHVLAQVWAPVKNRGRYVLTTSGQPFVLGPNSNGLNQYRMVSLTYMFSLDGERDGELGLPGRVFRKKLPEWTPNVQYYSSKEFSRLGHALHYNVQGTLALPVFEPSRQLCVGVVELIMTSPKINYAPEVEKVCKALEAVNLKTSEILNHETTQICNEGRQNALAEILEILTVVCETYKLPLAQTWVPCRHRSVLAFGGGFKKSCSSFDGSCMGKVCMSTSDLAVYVVDAHVWGFRDACAEHHLQKGQGVAGRAFQSGNLCFCRDVTRFCKTDYPLVHYARMFKLTSCFAVCLKSTYTGDDEYVLEFFLPPAITDKSEQDCLLGSLLQTMKQHYSSLKVVSETELCENNMSLEVVEASEDGMVYSKLEPIRIHHPAQISKDYLELNAPEQKVSLNSDFMENNEVDDGVERFQTLDPIPEAKTVKKSERKRGKTEKTISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKVNRSLTRLKHVIDSVQGADGSLNLTSLSPRPWPHQIPPIDIQLAKNCPPTSTSPLSNLQDVKIENRDAEDSAGSSTSRASCKVNPICETRFRLPTHNQEPSRQVALDDSDSSSKNMTNFWAHLTCQDTASPTILQHKLVSIKATYREDIIRFKISPESVSITELKQQVAKRLKLETAAFELKYLDDDREWVSVSCDADLSECLDTSAAKANTLRLSVHDVTFNFGSSCESSEETMMCL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Protein NLP6, AtNLP6, NIN-like protein 6, Nodule inception protein-like protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL4_STRPM
Sequence: MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGNEFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RSM18_SCHPO
Sequence: MLGRRIFSPAPNRGFILCNLIQSNNSTRRGFSDNRKFNERNSEASSNVGFQRRVRSNIPSYLSASVEEGDIYSPNDLLFETVKAKNQAKFYEPVREDCFKTVNENPMNYWKNPVILSRFVTELGRIKPRGDTGLTAKNQRLLSRAIRRARAAGIMPTKYKSVYSEN
What are the official names of this protein?
37S ribosomal protein rsm18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ASSY_GEOUR
Sequence: MAKKEVKKIVLAYSGGLDTSIILKWLKNEYGCEVITFSADLGQGDELTPIRDKAFATGADKVYIDDLREEFVRDFVFPMFRANAIYEGHYLLGTSIARPLIAKRQMEIAKIEGADAVSHGATGKGNDQVRFELGYYHFNPAITVIAPWRDWKLNSRQALINYAKKNDIPIPVTKKRPWSSDRNLLHISFEGAILEDTWAEAPENMYVLTKSPEKAPNKPQYVEIEFRNGNAVAVDGEAMSPAQLLAHLNFIGGEHGIGRVDLLENRSVGMKSRGVYETPGGTILREAHMAVEQITMDREVMHLRDSLIPRYAEMVYNGYWFSPEREMLQTMIDESQKTVNGVARVKLYKGHCRTVGRKSETDSLFNLDFATFEKDQVYNQKDAEGFIKLNSLRLRIRSLMQAAKKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOSSB_DROME
Sequence: MYNVECIPIKDIKPGLKNINVIFIVLEVGVATVTKENREVRNFKVGDPTACINVSIWDEPGKLIAPGDIVRLTKGYASIWRHCLTLYSGKNGEVFKIGEYCMVFNESVNMSEPKRAEQQAVANPAATPAGLPAGGGAPGLPAKGGATGIPQPAVAAAPGAPATQSAVTTAPAAAPAIAPQTTTKPGTRGGRGGGGRGGLKGERR
What are the official names of this protein?
SOSS complex subunit B homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-B family.
Protein: KATG_SALPB
Sequence: MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWDVNAVAARVLPVLEEIQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMSYEWKPTDESNELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLQ
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: FRDD_MYCTO
Sequence: MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECF_ENDTX
Sequence: MRFFRSVDIDFIGNRYKFFTISGLLLLLTVGAFIYRGGLNYGIDFTGGILMRISFQNEVGLQDVRIAVEESGINSFELQSSGNLVMIRIKKDLEAQEEFETLIKSSIQLRFPDNPVKIEGIEYIGPTVGEYLSKQAVYAFLFAFLVMIVYVAFRFKSSLWGIVSVVGIIHDIVISLGFVILANKEINITIVAALLTVVGYSINDTIVLFDRIKENLKLLVKEDFVAVINKSINEVLVRTIVTSLTVFIVACSLFFFGGEVMHTFAYIMIIGTVLGVFSTIFVCAPLICEWRIKTNKRLKIAIKQDGVRSK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YLH6_CAEEL
Sequence: MSKTAALTDIEKSKATISFWKFIAMFIQALFLIGLVEDLCYYHMFYSRQYFFLEILVTIHTGFSFIVFLIEHKPLIMLHVGYMTLLTIIPIAYMVMQGVEFGILIFDDYHILVFRDFHKFGCSIMFSLYYIGYIVVCFLFIEALEKKPVLPQVYSIKPKLVAAVNPSNNCNVYPML
What are the official names of this protein?
Uncharacterized protein C48B4.6.
Protein: ECHD1_CHICK
Sequence: MAVFLWRNLFQTTKARMLQQRRASLYNGAHDYDEELIKKKLQQFAGGSINLSKEHSGIGILTLNNSRLMNAFTGTMMLELQERVTELENWKDGKGLIICGAGNTFCSGSDLNAVKAISNSQDGMNMCMFMQNTLTRLMRLPLISIALIQGKALGGGAELTTACDFRLMTPGSEIRFVHKHMGLVPGWGGAARLVRIIGSRAALQLLSRAHGVDPERALHLGLSEGTLSSSDETGSLEEARAWLSQYTEGPASVIQAVKKVVTAGRELPLEAALRTEKDVFGTVWGGPANLEALTRRQK
What is the function of this protein?
Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading.  Also has methylmalonyl-CoA decarboxylase activity at lower level.
What are the official names of this protein?
Ethylmalonyl-CoA decarboxylase, Enoyl-CoA hydratase domain-containing protein 1, Methylmalonyl-CoA decarboxylase, MMCD.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SYW_UREPA
Sequence: MKRLISGIQPTNNLTLGNYLGAIKNFVDLQDDYEVFLFVADLHSLTPNIFDNTDFSTTKRQIIATYLAAGIDPKKTCLFYQSDILSIPLLAHILLCSTSIGELTRMTQFKDKSIKATKMANNTEMIPSGLLTYPTLMAADILTFNADVVPVGQDQKQHLELTRTLADRFNKRYGNTFKLPQVYIPKIGAKIMDLLDPNIKMSKSSKNLKGVIFLNDSKDIIFKKIKGALTDNLNKVKYDLTLQPGVSNLMTIYACLTNLSFKEIELKYQQQNYGVFKNDLANIVADFLEKLQQKISYWLNSPELDIMIDNSCERANDIAYQNVQLVLKHMQLK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_SALDC
Sequence: MSGQPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIDIDFIRISGLRGKGVKALLAAPLRIFNAWRQARAIMKRFKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNQWLAKIATTVMQAFPGAFPNAEVVGNPVRTDVLALPLPQVRLAGRDGPIRVLVVGGSQGARVLNQTMPQVAARLGDTVTIWHQSGKGVQHTVEQAYAGVGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNALPLENAGAAKIFEQPQFTVEAVADTLAGWSRGALLTMAERARAVSIPDATERVASEVSRVART
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DMA_TREPA
Sequence: MSRSDTARPFVKWAGGKRALAPTLFAHMPQTFGSYFEPFVGGGALFWHLCACTRVRLHDIYLSDINWPLLCAYAAVRDRVEELIVRVGQHIACHTPTYYRLARRKFAVCEHPLEVAALFLYLNRSCYNGLYRVNKAGQFNVPLGRAAPASPFLNTTAPTPRSTQPAAQVGHLAIRIDEENLRSCARALANTTLNCQHFSCIQPARGDFVYLDPPYLGTFSAYDKTGFDRAAHESLAAFCMHLDARGVLFMLSNSDCPEVRAWYRPFRVQQLNAPRCIARSAHARGKRCEVLITNYPCADTATP
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 on both strands (Probable) (PubMed:12654995).  Directly involved in methyl-directed DNA mismatch repair, DNA replication, and gene expression (By similarity).
What are the official names of this protein?
DNA adenine methylase, DNA adenine methyltransferase, Deoxyadenosyl-methyltransferase, M.TpaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: NAS8_CAEEL
Sequence: MRRNDLLNNKITIFLSSLSLFVIIIPIYAAEKDLLPPSTSSETFLTDEDFLRPLNDDETFLTEKDFKNGEKLGEDHVPAGSILWKQVYKKGDIRGKAAWKLDPKNSESLRRNGVITGTRKWPNGRIPYVISNQYNDRERAVLARSFQAYHDKTCVRFVPRTAVDNDYLYIGKIDGCYSDVGRAGGRQELSLDNGCLQYDTAIHELMHSVGFYHEHERWDRDEHITILWHNIDREAYDQFGKVDLAESSYYGQLYDYYSIMHYDSLAFSKNGFETMVAKQSEMTAVIGAAIDFSPIDILKMNLMYQCSDVKLPPTVVGTTDKTIVPVPAPSVTVVEDDCRDRTNLCWRWIDRCKSFFFEQIMKEFCSLSCGYCTPKALQTAKASPPNYSNTLLTKSSTSYLQHG
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-8, Nematode astacin 8.
What are the subcellular locations of this protein?
Secreted.
Protein: ZPLD1_SALSA
Sequence: MEQICLIILLISKALSVGAQFNGYNCDANFHSRFPAERDISVYCGVQTITLKINFCPVLFSGYTDTDLALNGRHGDAHCRGFINNNTFPTVVLFSISLATLETCGNALVVSTAQGPNAYGNLSLVQIGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSAAAISVKDSNGTFVSTLSLLLYNDSSYVQQLSIPMAGLTLKTRVFAAVKATNLDRRWNVLMDYCYTTASGNPNDELRYDLFFSCDKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPMLMPICGSRKKRDVSERTESNSASGNAIITAGPIITRSDDTPMNNSQLAQLNSPVFRMNTVTSALISGIIILGVMSLCFFILSLTLLKGKRAPPTILSGARNPAFN
What is the function of this protein?
Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
What are the official names of this protein?
Zona pellucida-like domain-containing protein 1, ZP domain-containing protein 1, Cupulin.
What are the subcellular locations of this protein?
[Zona pellucida-like domain-containing protein 1]: Cytoplasmic vesicle membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Zona pellucida-like domain-containing protein 1, secreted form]: Secreted, extracellular space, extracellular matrix.
Protein: RL10_CAMJJ
Sequence: MTRSEKVEIIAKLEEGFKASEAIVVCNYRGLSTKKLEELRNNARENNVKVQIVKNTLANIALNNSGKTGLVLKDTNIYLWGEDQLSVSKVAAKFEENNDKFEIKTAHIEGEVADVAKVKALAKMPSRNELLAMLLQVWNAPITNFTIGLNALKNKKESE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HUTU_ENT38
Sequence: MSSGKYRQQEIRAPRGTTLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVYGGIGRAARNWECYDAIVDSLTHLESDETLLVQSGKPVGVFKTHENAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRTRYVDEQADNLDDALARINKYTSQGKTVSIALCGNAADIVPELVARGVRPDLVTDQTSAHDPLHGYLPTGWSWEEYQQKAKTDPEGTVLAAKKSMAEHVRAMLAFSDMGVPTFDYGNNIRQMAKEIGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVADDAHLHHWLDMARERINFQGLPARICWVGLEWRQKLGLAFNEMVRSGEVSAPIVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIARVLHNDPATGVMRHADAGYDIAIDCAKEQGLNLPMIAATQGKH
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM52_HUMAN
Sequence: MARGPLAARGLRLLLPLLPLLPLLPLPQVALGFADGSCDPSDQCPPQARWSSLWHVGLILLAVLLLLLCGVTAGCVRFCCLRKQAQAQPHLPPARQPCDVAVIPMDSDSPVHSTVTSYSSVQYPLGMRLPLPFGELDLDSMAPPAYSLYTPEPPPSYDEAVKMAKPREEGPALSQKPSPLLGASGLETTPVPQESGPNTQLPPCSPGAP
What are the official names of this protein?
Transmembrane protein 52.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VGRG3_AERHY
Sequence: MADSTGLQFTVKVGALPESTFVVAEFALDEGLNRPFNLRLELASRQPDIDFGAVLDQPCELLVWYNGELQRRVCGVVSDMAQGDSGFRRTRYQLLVLPALWRLSLRQNSRIFQAQKPDEILSILLQEHGITDYAFALKNEHAKREYCVQYRETDLDFVNRLAAEEGMFYFHEFEAGKHRIVFADDAAALTQGPELFFNLGNRSLEQGPYVRQFHYREAVRPSDVELKDYSFKTPAYGLSHKKQGADLDHQRDTYQHFDFPGRYKQGGSGKAFAQHRLDALRNDAVAGSGKSNCAALQPGQTFSLTEHPNGGLNTDWQVVRIQHTGLQPQALEEEGGSGPTVYHNEFGVVKASSTWRARIGSPEALHKPMVDGPQIAMVVGPEGEEIYCDEHGRVKLQFPWDRYGSSNDQSSCWVRVSQGWAGGQYGMMAIPRIGHEVIVSFLEGDPDQPIVTGRTYHATNRPPYELPANKARTVLRTETHQGEGFNELRFEDQAGQEEIYIHGQKDLNVLIENNAVWHIKHDEHRDIDNERVTRIKANDHLTVEGEKRDQIKADYSLTVDASLHQKLGQSLLVEAGQEVHIKVGDKLVLEAGSEITLKGGGSFVKVDPSGIKLMGPAIKLNAGGSAGSGSGWGGKAPVVPKGVEVVKAPELVELVKAIPTEKAMEALLKEQGPAQTFFVPSR
What is the function of this protein?
Part of the type VI secretion system specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection.  Plays an essential role in bacterial mobility and biofilm formation.
What are the official names of this protein?
Type VI secretion system spike protein VgrG3.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
Protein: HIS1_KLEPN
Sequence: MLDNSRLRIAIQKSGRLSEDSRELLSRCGIKVNLHTQRLIALAENMPIDILRVRDDDIPGLIMNGVVDLGIIGENVLEEELLNRRAQGEDPRHFNPRRLD
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.