PharMolix/UniProtQA huggingface dataset:
Protein: DEOC_AERS4
Sequence: MTDLKLAAQRALNLMDLTTLNDDDTDQKVVDLCRKAKSPAGLTAAVCIYPRFIPIARKTLREIGAADVRIATVTNFPHGNDDIEIAVAETRAAVAYGADEVDVVFPYRAFMAGNEQVGFDLVKACKEACGDKALLKVIIETGELKEEALIRRASEICIDAGADFIKTSTGKVPVNATPEAARIMMEVIKAKNPKVGFKPAGGVKDAAVAGQYLAMAEEILGKEWVSARTFRFGASSLLASLLATLGHGDKPANTSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LV539_HUMAN
Sequence: MAWTPLLLLLLSHCTGSLSQPVLTQPTSLSASPGASARFTCTLRSGINVGTYRIYWYQQKPGSLPRYLLRYKSDSDKQQGSGVPSRFSGSKDASTNAGLLLISGLQSEDEADYYCAIWYSSTS
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 5-39.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: SYFA_RICCN
Sequence: MENIETILRLAEDKILLVQNLKALQEYKVEFLGKNGIVTGELKKLGSLNEQERKEFGLKINKLKDKIQNIIKAKAEILEEQELNFKLAADKIDLTIPARRYKQGSIHPITQCSEELIQVFSQFGFTIENGPNIENDFHNFTALNFEDDHPARQMHDTFYLKSQENNKPLLLRTHTSTVQIRAMKNGKPPFRFIAPGRTYRSDSDMTHTPMFHQIEGLVMDKNINMGHLKYVITTFIKSFFENSNIELRFRPSFFPFTEPSAEVDIRMNKNDKWLEVLGCGMVHPNVLKNVGIDSSEYQGFAFGLGVERFAMLKYNIKDLRQFFEGDMRWLKHYNFGSFDIPNLAGGLTK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR907_MIMIV
Sequence: MKLNNFIDFSSILELNYNDFLPLDDNHKSYTYEDNIQLQDDSEARFLIQRAKDSLLSHTKIKDKYIRPKCEWDECEYSCKFYLSTDRKFYCVYFSYDLDFTILYFYGIIEKKTGKHLVVSHEETSDNVYPMMNHHMFNYEWDNYEHEDLRYPPYKYEDDPLELICCLEDQFNVFYEEMCKKNYNDNGSDDSNDDND
What are the official names of this protein?
Uncharacterized protein R907.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R24/R907 family.
Protein: PSBE_NOSP7
Sequence: MSGTTGERPFSDIITSVRYWVIHSITIPALFIAGWLFVSTGLAYDAFGTPRPNEYFTPARQEVPIVKNRFEAKKQVEQFIGK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DIDAA_ERIMA
Sequence: MNSANPCCDPITCKPKKGEHCVSGPCCRNCKFLNPGTICKKGRGDNLNDYCTGVSSDCPRNPWKSEEED
What is the function of this protein?
Extremely potent and selective inhibitor of integrin alpha-5/beta-1 (ITGA5/ITGB1).  Partially inhibits adhesion of cells expressing alpha-IIb/beta-3 (ITGA2B/ITGB3), alpha-V/beta-3 (ITGAV/ITGB3), and alpha-4/beta-1 (ITGA4/ITGB1) to appropriate ligands only at concentration higher than 500 nM.  Weakly inhibits ADP-induced platelet aggregation.
What are the official names of this protein?
Disintegrin EMF10A, EMF-10A, Eristocophin I, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_BACVZ
Sequence: MARYTGPSWKLSRRLGISLSGTGKELEKRPYAPGPHGPGQRKKLSEYGLQLQEKQKLRHMYGVNERQFRTLFDKAAKMTGKHGENFMILLDARLDNVVYKLGLARTRRQARQLVNHGHILVDGSRVDIPSYQVKPGQTIGVREKSRNLSIIKESVEVNNFVPEYLTFDAEKLEGTFTRLPERSELAPEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RECX_VIBC1
Sequence: MYQKLQAPTLSSKEAAIQLLSRRDHGQYELYQKLALKGYEEADIEAAINFCLDHNYLDDLRYAKSQVRQHVYKGHGERRIRQELKQKRVAESIIDMAMAEEPQDWFELARMAAEKKFKGIKAKDQKEYAKQVRFLQYRGYSFDQISYALSFEDED
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZUPT_SALTY
Sequence: MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
What is the function of this protein?
Mediates zinc uptake (PubMed:24430377).  May also transport other divalent cations (Probable).  Contributes to zinc acquisition during infection and plays a role in the ability of S. typhimurium to colonize the host tissues (PubMed:24430377).
What are the official names of this protein?
Zinc transporter ZupT, Low affinity zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAP2_PYRAB
Sequence: MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
Protein: CPIN1_TETNG
Sequence: MATLGIKAGENVLMVWAQPSKPATLKDYAEELSSIVGTDGKVSVENVDRLLLSSHSASTFDCAVSCVLADSSAVHSLDTLAELARVLKPGGKLILEEVVTGAEAQRERTSEKLVSTLKLSGFTSVTEISKAELSPDALSAIRTATGYQGNALFRIRMSASKPDFEVGSSSQIKLSFGNKAPRPADKPAPDPNTVKMWMLSANDMNDDDLDLVDSDSLLDEEDLKKPDPSSLKASTCGEAAGKKKKACKNCTCGLAEELEQESKEKEKTNLPKSACGSCYLGDAFRCASCPYLGMPAFKPGEKILLDNKTLTDA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.  Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1.  NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.  Has anti-apoptotic effects in the cell.  Involved in negative control of cell death upon cytokine withdrawal.  Promotes development of hematopoietic cells.
What are the official names of this protein?
Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: WNT16_MOUSE
Sequence: MDRAALLALPSLCALWAAVLSLLPCGTQGNWMWLGIASFGVPEKLGCADLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMVATTTSTQLATAPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSPSEGWHWGGCSDDVQYGMWFSRKFLDLPIRNTTGKESRVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHFLKDKYENSIQISDKTKRKMRRREKDQRQTPILKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-16.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL36_STAHJ
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICDNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TF2B_SULTO
Sequence: MSESNKSQASATPCPPDKIVFDEERGEYICTETGEVIEERAIDQGPEWRAFTPEEKEKRSRVGGPLNQTIHDMGISTVIDWKDKDAMGRTLDPKRRLEVLRWRKWQIRARIQSSIDRNLAQAMNELERIGNLLNLPKAVKDEAALIYRKAVEKGLVRGRSIESVVAASIYAACRRMKMARTLDEIAQFTKANRKEVARCYRLILRELDINVPVSDPKDYVTRIGSLLGLSGSTMKMAIDIIEKAKESGLTAGKDPAGLAAAAIYIAALLNDERRTQKEIAQIAGVTEVTVRNRYKELTQELKIQIPNQ
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: CCME_RUEST
Sequence: MKSLKKQRRIQIIALATVALVGSTALIGYAMRDGINYFRSPSQVMETPPEPTETFRIGGLVEEGTLQRGQGEAVRFSVTDGGASVPVTYVGVLPDLFEENQGMVGTGRYVNGVFEASEILAKHDETYMPKEVVDALKEQGVYREGDS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: YCIB_VARPS
Sequence: MKLILDFFPILLFFGAYKLADIYTATGVLMAATVLQMGIIYAMERKLQAMQKATLVLILLFGTLTLVLHDDRFIKWKPTVLYGAMAIALAVALWALKKNFLKMLLGSQLQLPDRIWGRLNVAWIGYCLFMAAINGYVAAYFTTEAWVNFKLWGYVFPIVFLVAQGLYISPHLKNDEPSV
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAL1_CRYNB
Sequence: MAGVNVGDDKLVFESSEAVTVAPTFEALNLKEDLLRGIYAYNFEKPSAIQQRAIIPIIRGRDVIAQAQSGTGKTATFSISMLQSIDTNLRETQALVLSPTRELAVQIQTVVLALGDYMNVSCHACIGGTSVGEDIRKLEAGQQVVSGTPGRVFDMIRRRNLRTKDIKMLILDESDELLNKGFKDQIYDIYRYLPPATQVVVVSATLPHDVLEMTTKFMTDPVRILVKRDELTLEGIKQFFVAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTEKMREANFTVSSMHGEMVQKERDAIMAEFRGGQSRVLITTDVWARGIDVQQVSLVINYDLPTSRENYLHRIGRSGRFGRKGVAINFVTVDDVRILRDIEQYYSTQIDEMPMNVAELT
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase FAL1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HUTI_STRP1
Sequence: MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGTQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQLTVDRGRIL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YZ09_AQUAE
Sequence: MEHFIDTYLYELRKVRDEKTIKKKEYLLKHLQDYSEDLPAFDQSEIFSFYEYLKNKNLKETTIRDILKEVRLFYEWLQEQGLNLKFDEKALKKLFQSKKSQEALKSKKKYYSDDEINLILNAIRGAVEGISTKHPIYYILTIFLLCSGLRISEAVKVRKKDFEVKRILTEEGEEKEVWFVKVREGKFGKERKALIYFFRPEWKRIFEERLKKLKPEDFFFTYAVKYPKSVKVFTLTDKTAKWFYWKLEKELREKGYEIEVNAHRFRNTYITKLATKGFPVNLIADWVGHSKISTTMDVYMEAEREKQLEAILERI
What is the function of this protein?
May function as an integrase.
What are the official names of this protein?
Probable integrase/recombinase aq_aa09.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: FUT8_ARATH
Sequence: MKVVITVVTCLFLLSVMQLSFFNIFNYQLLDATTNGSKDSRKSKDKLLGGLLTADFDEDSCLSRYESSLYRKPSPYKPSRYLVSKLRSYEMLHKRCGPGTEAYKKATEILGHDDENHSTKSVGECRYIVWIAVYGLGNRILTLASLFLYALLTDRIMLVDQRTDISDLFCEPFPGTSWLLPLDFPLTDQLDSFNKESPRCYGTMLKNHAINSTTTESIIPSYLCLYLIHDYDDYDKMFFCESDQILIRQVPWLVFNSNLYFIPSLWLIPSFQSELSKLFPQKETVFHHLARYLFHPTNQVWGMITRSYNGYLSRADERLGIQVRVFSKPAGYFQHVMDQILACTQREKLLPEVFVLETQVTNTSRSSKLKAVLVTSLYPEYSEILRQMYWKGPSSTGEIIQIYQPSQEIYQQTDNKLHDQKALAEIYLLSLTDYIVTSDSSTFGYVAQGLGGLKPWILYKPKNHTAPEPPCVRAVSMEPCFLRAPLYGCQAKKVNITPFVMYCEDRITGLKLVDSN
What is the function of this protein?
May be involved in cell wall biosynthesis.  May act as a fucosyltransferase.
What are the official names of this protein?
Probable fucosyltransferase 8, AtFUT8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 37 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: FCSK_HUMAN
Sequence: MEQPKGVDWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTLLLAVEDPEKRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPEAPVEALVCNLDCLLDIMTYRLGPGSPPGVWVCSTDMLLSVPANPGISWDSFRGARVIALPGSPAYAQNHGVYLTDPQGLVLDIYYQGTEAEIQRCVRPDGRVPLVSGVVFFSVETAERLLATHVSPPLDACTYLGLDSGARPVQLSLFFDILHCMAENVTREDFLVGRPPELGQGDADVAGYLQSARAQLWRELRDQPLTMAYVSSGSYSYMTSSASEFLLSLTLPGAPGAQIVHSQVEEQQLLAAGSSVVSCLLEGPVQLGPGSVLQHCHLQGPIHIGAGCLVTGLDTAHSKALHGRELRDLVLQGHHTRLHGSPGHAFTLVGRLDSWERQGAGTYLNVPWSEFFKRTGVRAWDLWDPETLPAEYCLPSARLFPVLHPSRELGPQDLLWMLDHQEDGGEALRAWRASWRLSWEQLQPCLDRAATLASRRDLFFRQALHKARHVLEARQDLSLRPLIWAAVREGCPGPLLATLDQVAAGAGDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWMRPFSYLECGDLAAGVEALAQERDKWLSRPALLVRAARHYEGAGQILIRQAVMSAQHFVSTEQVELPGPGQWVVAECPARVDFSGGWSDTPPLAYELGGAVLGLAVRVDGRRPIGARARRIPEPELWLAVGPRQDEMTVKIVCRCLADLRDYCQPHAPGALLKAAFICAGIVHVHSELQLSEQLLRTFGGGFELHTWSELPHGSGLGTSSILAGTALAALQRAAGRVVGTEALIHAVLHLEQVLTTGGGWQDQVGGLMPGIKVGRSRAQLPLKVEVEEVTVPEGFVQKLNDHLLLVYTGKTRLARNLLQDVLRSWYARLPAVVQNAHSLVRQTEECAEGFRQGSLPLLGQCLTSYWEQKKLMAPGCEPLTVRRMMDVLAPHVHGQSLAGAGGGGFLYLLTKEPQQKEALEAVLAKTEGLGNYSIHLVEVDTQGLSLKLLGTEASTCCPFP
What is the function of this protein?
Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.
What are the official names of this protein?
L-fucose kinase, Fucokinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family.
Protein: DAZ3_HUMAN
Sequence: MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
What is the function of this protein?
RNA-binding protein that plays an essential role in spermatogenesis.  May act by binding to the 3'-UTR of mRNAs and regulating their translation.
What are the official names of this protein?
Deleted in azoospermia protein 3.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Protein: SYQ_CUPMC
Sequence: MSHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGHAKSICVNFGLARDYAGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHLYFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNFSEPGKPSPFRDRSVEENLKLFREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKRRLKQLVDEQRVTGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAVRDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPKQPEMGRRVFPLSRELWIEREDFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADSVKVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLRDAKPEDRFQFERHGYFVADRVDSQPGKPVFNRTVGLKDSWGK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_BUCA5
Sequence: MNKKTRIAITGPIGRMGRMLIKEIQNNKHSHLTVAVVQKKHQLIGQDIGRIIGIGEIGVLISDELNIKKNDFDVLIDFTRPAGTLEYLKYCNKFKKNIVIGTTGFSKEEIDIIKSYSQKIAIIIASNFSIGINLLFQLIKKTTQIIGKDSDINILEYHHRNKIDAPSGTALEIGEVISKVMNWNLNQDSIYYQKGITGIRDAKKIGFSIVRAGNIVGKHTVMFSSCDEEIKITHTASNRMSFARGAIQSALWIHKKNTGLFDMTDVLSL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFH1_DROME
Sequence: MLSCLAPSSSRFGQEDTIIQQSMPSTSPFAMQFPSLASTLLHHNQSPKHSNPGSSGIQDAHPNQPGAAADAFLVKCTQCHKRFPEYQSLSEHIASEHPHDKLNCGAAQPESDAEDEQSNMSGSSRRYAKSPLASNNNSSTANANNNSTSSQSMNNNSELAKNHNSANKMSPMCSPGSLTPGDLFAQLQHPPPQLPPHLHAQFMAAAASLAMQSARTASSPSQQQQQQLQQQQQLQQQQQHQMAMQQLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFASREQLEQHEQLHSPCGPAAVSNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGSASSASRRSPSDHGKGKLPEQPSLPGLPHPMSYFASDAQVQGGSAAPAPFPPFHPNYMNAALLAFPHNFMAAAAGLDPRVHPYSIQRLLQLSAAGQQQREEEREEQQKQQQHDEEETPDEPKLVMDIEEPETKEMAPTPEATEAATPIKREESREASPDPESYRSSSQAIKQEQEPLNVAEERQTPVEEHAPVEHAADLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHFQQQQATSFALASASEEDEEDEEMDVEEEPRQESGERKVRVRTAINEEQQQQLKQHYSLNARPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERKMQSFQNNQAAGAAPPMPIDSQASLTREDQPLDLSVKRDPLTPKSESSPPYIAPPSGEALNPEAINLSRKFSTSASMSPASISPSSAAALYFGAAPPPSPPNSQLDSTPRSGQAFPGLPPYMLPMSLPMEALFKMRPGGDFASNHALMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDEFGAGVLMPPKPRRGKAETHGHAGDPDLPYVCDQCDKAFAKQSSLARHKYEHSGQRPYQCIECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
What is the function of this protein?
Involved in the development of the embryonic central nervous system, embryonic mesoderm and adult musculature.
What are the official names of this protein?
Zinc finger protein 1, Zinc finger homeodomain protein 1.
What is the protein family that this protein belongs to?
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENLYS_BPA51
Sequence: MVKYTVENKIIAGLPKGKLKGANFVIAHETANSKSTIDNEVSYMTRNWKNAFVTHFVGGGGRVVQVANVNYVSWGAGQYANSYSYAQVELCRTSNATTFKKDYEVYCQLLVDLAKKAGIPITLDSGSKTSDKGIKSHKWVADKLGGTTHQDPYAYLSSWGISKAQFASDLAKVSGGGNTGTAPAKPSTPAPKPSTPSTNLDKLGLVDYMNAKKMDSSYSNRDKLAKQYGIANYSGTASQNTTLLSKIKGGAPKPSTPAPKPSTSTAKKIYFPPNKGNWSVYPTNKAPVKANAIGAINPTKFGGLTYTIQKDRGNGVYEIQTDQFGRVQVYGAPSTGAVIKK
What are the official names of this protein?
Endolysin, Probable N-acetylmuramoyl-L-alanine amidase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HMGBH_CAEEL
Sequence: MNSGYSANIFPSSSSPTLYQSHQLQPNPSATMYQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVSVAAYGGEDAMRKRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAEMQKMSGMDHYDDDNIHHVVHVEDINSQNIS
What are the official names of this protein?
High mobility group protein 1.2.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
Protein: BAF_HUMAN
Sequence: MTTSQKHRDFVAEPMGEKPVGSLAGIGEVLGKKLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL
What is the function of this protein?
(Microbial infection) Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome (PubMed:9465049, PubMed:11005805, PubMed:16680152).  EMD and BAF are cooperative cofactors of HIV-1 infection (PubMed:16680152).  Association of EMD with the viral DNA requires the presence of BAF and viral integrase (PubMed:16680152).  The association of viral DNA with chromatin requires the presence of BAF and EMD (PubMed:16680152).
What are the official names of this protein?
Barrier-to-autointegration factor, Breakpoint cluster region protein 1.
What is the protein family that this protein belongs to?
Belongs to the BAF family.