PharMolix/UniProtQA huggingface dataset:
Protein: LPXC_PSEA6
Sequence: MIKQRTIKQSVQETGIGLHKGDKVTMTLRPAPANTGIVFRRVDLEPHADIPARAEAVGDTMLCTCITNADGVSISTVEHLASALAGLGIDNIIVEVDSDELPIMDGSASPFIFLLQSVGIEELNAPKQFIKIKKAIKVKDGDKWAELRPHDGFRVDFRIDFDHPAISQTRQHMVLDFDSSSYVDEVSRARTFGFMKDLEYMNANNLALGGSMANAVALDEYRVLNPEGLRYSDEFLKHKILDAIGDLYLGGHSIIGELVAYKTGHGLNNKLLNALLQNQACWEFVSYDNSEELPIRFASPILAN
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: LUXB1_PHOLU
Sequence: MKFGLFFLNFINSTTVQEQSIVRMQEITEYVDKLNFEQILVYENHFSDNGVVGAPLTVSGFLLGLTEKIKIGSLNHIITTHHPVAIAEEACLLDQLSEGRFILGFSDCEKKDEMHFFNRPVEYQQQLFEECYEIINDALTTGYCNPDNDFYSFPKISVNPHAYTPGGPRKYVTATSHHIVEWAAKKGIPLIFKWDDSNDVRYEYAERYKAVADKYDVDLSEIDHQLMILVNYNEDSNKAKQETRAFISDYVLEMHPNENFENKLEEIIAENAVGNYTECITAAKLAIEKCGAKSVLLSFEPMNDLMSQKNVINIVDDNIKKYHMEYT
What is the function of this protein?
Light-emitting reaction in luminous bacteria.  The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.
What are the official names of this protein?
Alkanal monooxygenase beta chain, Bacterial luciferase beta chain.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: KTHY_HISS2
Sequence: MKTGKFIVIEGLEGAGKSSTHQVVVNTLTEFGIHEVVFTREPGGTPLAEKLRYLIKHEAEELVTAKAELLMLYAARVQLVENVIKPALARGKWVVGDRHDLSSQAYQGGGRGLDRHLMTTLKNAVLGDFKPDFTLYLDIEPEIGLARAKGRGELDRIEQQNLDFFHRTRERYLQLVQQDPNAVLINAGQPIELVQQDIRKAVQKFIEENV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RBFA_COXBU
Sequence: MSQRQQRVADLIHQQLAELLKKEVRDSRLSKISLTAVSISPDLKQAKVFYSLLENQNEKEVQKALNKATGYLRHLLAQATVLRYVPKLEFVYDESIERAHRISLLIERALKKDDSDESS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB10B_ARATH
Sequence: MQPSNDPAIVDMAAAEKEKKRPSVSFLKLFSFADFYDCVLMALGSIGACIHGASVPVFFIFFGKLINIIGLAYLFPQEASHKVAKYSLDFVYLSVVILFSSWLEVACWMHTGERQAAKIRKAYLRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVGNFMHFISRFIAGFAIGFASVWQISLVTLSIVPFIALAGGIYAFVSSGLIVRVRKSYVKANEIAEEVIGNVRTVQAFTGEEKAVSSYQGALRNTYNYGRKAGLAKGLGLGSLHFVLFLSWALLIWFTSIVVHKGIANGGESFTTMLNVVIAGLSLGQAAPDISTFMRASAAAYPIFQMIERNTEDKTGRKLGNVNGDILFKDVTFTYPSRPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIERFYEPTDGAVMLDGNDIRYLDLKWLRGHIGLVNQEPVLFATTIRENIMYGKDDATSEEITNAAKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRISISRAIVKNPSILLLDEATSALDAESEKIVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDELISNPDGAYSSLLRIQEAASPNLNHTPSLPVSTKPLPELPITETTSSIHQSVNQPDTTKQAKVTVGRLYSMIRPDWKYGLCGTLGSFIAGSQMPLFALGIAQALVSYYMDWETTQNEVKRISILFCCGSVITVIVHTIEHTTFGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNTSSMLASRLESDATLLRTIVVDRSTILLENLGLVVTAFIISFILNWRLTLVVLATYPLIISGHISEKIFMQGYGGNLSKAYLKANMLAGESISNIRTVVAFCAEEKVLDLYSKELLEPSERSFRRGQMAGILYGVSQFFIFSSYGLALWYGSILMEKGLSSFESVMKTFMVLIVTALVMGEVLALAPDLLKGNQMVVSVFELLDRRTQVVGDTGEELSNVEGTIELKGVHFSYPSRPDVTIFSDFNLLVPSGKSMALVGQSGSGKSSVLSLVLRFYDPTAGIIMIDGQDIKKLKLKSLRRHIGLVQQEPALFATTIYENILYGKEGASESEVMEAAKLANAHSFISSLPEGYSTKVGERGIQMSGGQRQRIAIARAVLKNPEILLLDEATSALDVESERVVQQALDRLMRDRTTVVVAHRLSTIKNSDMISVIQDGKIIEQGSHNILVENKNGPYSKLISLQQRQRHHP
What are the official names of this protein?
ABC transporter B family member 10, ABC transporter ABCB.10, AtABCB10, Multidrug resistance protein 10, P-glycoprotein 10.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIAB_AZOC5
Sequence: MQEPRKLYVKSFGCQMNVYDSQRMADALAKEGYVETQDPADADLVILNTCHIREKAAEKVYSELGRLRKAKQDAGSDTTIAVAGCVAQAEGAEIMKRAPVVDLVVGPQSYHRLPEMLARVRDGKRVVDTEFPAEDKFDHLPAPSAAATKKRGPTAFVTVQEGCDKFCTFCVVPYTRGAEVSRSVSKIVGEARALVDQGVREITLIGQNVNAFHGEGPDGRTWGLGRLLEELAGINGLARLRYTTSHPRDMDDGLIAAHRDLPQLMPYLHLPVQSGSDRILAAMNRKHGREIYFEIIDKLRAARPDIALSSDFIVGFPGETEADFEDTLDLARRVGFASAYSFKYSIRPGTPAAEHDHQLSEEVKSERLARLHQVLEASKTAFDRACMGRRFDILLEKPGRLPGQLIGRSPYLQSVVVTAPGAGIGDFVTVDITDVGPNSLAGQVVDAVEDRGRTSDRPLVAMEA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF6_METJA
Sequence: MTMIIRKYFSGIPTIGVLALTTEEITLLPIFLDKDDVNEVSEVLETKCLQTNIGGSSLVGSLSVANKYGLLLPKIVEDEELDRIKNFLKENNLDLNVEIIKSKNTALGNLILTNDKGALISPELKDFKKDIEDSLNVEVEIGTIAELPTVGSNAVVTNKGCLTHPLVEDDELEFLKSLFKVEYIGKGTANKGTTSVGACIIANSKGAVVGGDTTGPELLIIEDALGLI
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: PYRK_STRTD
Sequence: MILIEDLTVVSQREIAPRIFEMVLKGEMVADMQLGQFVHLKVPDPSKLLRRPISISEIDYNKKEATIVYRVEREGTAILSKMVAGQTIDTMGPQGNGFDISIIEAGQKALLVGGGIGVPPLVETAKQLKAKGVEVVSVIGFANKNAVILEDKLRACGDVYVTTDDGSYGIKGYVSTVIDNFDWTPDAVYSCGAPGMLKYVDSKFENHPHAYVSMEARMACGMGACYACVVHVKGETDAKNLRVCEEGPVFPTGKVIV
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: VATE_CLOB1
Sequence: MSNLENLTSKIIEDANKEAEELLSEAKKEENKIVDEKVKKGNKAKEQIIEKSKREAKTKAERIISNTHLKIRNNKLEAKQEMINKVFDEAVIKLQNLSKDEYLDFVKSSILSLDIEGDEEIIISPNDKDKMDVNFMLTLNNKLKAKGKKGLLKISNENRNIKGGFILYKNGIEINNSFEALVDSLRDELEQEIIEALFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PUR1_BACSU
Sequence: MLAEIKGLNEECGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVEEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: Y060_RICFE
Sequence: MLRIVKKLGIILFVSSISINSFAKSMYDDVDSAPDYDSTPYYENEGSLVFKMRLGGVFSSAKQKGLPTPTSPQPVPVGEVAKNGYGGDASTTIFFNNYLATELSLGFNVLRTKYTSLAAVAHNYGVNNVKLGKNKPIYMIPATVTGQFHIAPYGGIRPYVGVGYHGSYMLTQATGLKIRNGHGLVGQIGVDFYAKDDTLINIDVRQFFLNPKLEYKPNLVGTKTVTSKVKLNPLIVSIGIGFTF
What are the official names of this protein?
Putative outer membrane protein RF_0060.
What is the protein family that this protein belongs to?
Belongs to the OmpW/AlkL family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: WSB2_HUMAN
Sequence: MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
WD repeat and SOCS box-containing protein 2, WSB-2, CS box-containing WD protein.
Protein: GGYF2_MOUSE
Sequence: MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLEKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGGTVVGAPRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRPNFEESGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSTGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVEEGEERSDSDSSHNEEAKEPDKTNRREGEKTDRAGAEASEEVPQTSLSSARPGTPSDHQPQEATQFERKDEPKAEQVEKAEEENRSENSLSAKVPSRGDETVPASQQPSTPLPPDTASPLLILSPPVPTPSSASRPVETAAVEAPGMSSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLTSKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQALKMRMSDQNIIPSVTRSVSVPDTGSIWELQPAASQPAVWEGGSVWDLPLDTTAPGPSLEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELELQRQKDLMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTATCQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQQKLSGWGNVSKPAGTTKSLLEIQQEEARQMQKQQQQQQQQQQQHQQSNRARNSTHSNLHTSLGNSVWGSINTGPSNQWASELVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQFLERRAKQKVNQQRQQQQQQQQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
What is the function of this protein?
Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:26763119).  In the 4EHP-GYF2 complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (PubMed:26763119).  Also recruits and bridges the association of the 4EHP complex with the decapping effector protein DDX6, which is required for the ZFP36/TTP-mediated down-regulation of AU-rich mRNA (By similarity).  May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153).
What are the official names of this protein?
GRB10-interacting GYF protein 2, PERQ amino acid-rich with GYF domain-containing protein 2, Trinucleotide repeat-containing gene 15 protein.
What is the protein family that this protein belongs to?
Belongs to the GIGYF family.
Protein: GCS2_BURO0
Sequence: MALETFVNSEPFTFGVELEIQVVNTHNYDLTKAASDLMRLIQGETFPGNITPEITESMIELSTGICHSHEQAVSELHAIRDVLVKAADQLNVGLAGGGTHAFQQWSDRQIYDAPRFQYISELYGYLAKQFTVFGQHVHIGCPDPDSALFLLHSMSRFIPHFIALSASSPFVQNVDTGFHSARLNSVFAFPLSGRAPFVLTWDSFEEYFTKMVNTGVVNSMKDFYWDIRPKPGYGTIEVRVMDTPLSVDRAAAIACYIQTLARYLLTDRPLKLSEDDYLVYTFNRFEACRFGLEGTCVNPQTGERRTIAEDILDTLDRIAPHAAALGSRAALDEIGALAKARVNDASWLRTVFKQEKSLNETVRQQCLRWRE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: MDH_LEGPC
Sequence: MINNRVRVAVTGAAGQIGYALVFRIASGQMFGPNTEVELNLLELEPALPSLEGVAMELDDCAFPLLKRIVCTADLNKAMDGVNWALLVGSVPRKQGMERSDLLQINGGIFTKQGQAINDYASDDVRVFVVGNPCNTNCLIAMNHAKDVPSDRFYAMTTLDELRARTQLAKKAGVDITAVTQMTIWGNHSATQYPDFYNAKINGTSAAQVINDETWLKETFVSTVQQRGAAVIKARGSSSAASAANAIITGVNHLVTDTPAGESFSMCRRSKGEYGVDEGLIFSFPCRREHGELKVVENLEFNDFGRERFNTTLNELRSERDTVKSLGLLD
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: CDDTR_MYCTU
Sequence: MREFQRAAVRLHILHHAADNEVHGAWLTQELSRHGYRVSPGTLYPTLHRLEADGLLVSEQRVVDGRARRVYRATPAGRAALTEDRRALEELAREVLGGQSHTAGNGT
What is the function of this protein?
May have transcription regulation and metal-detoxifying functions through which it may enhance intracellular survival of mycobacteria.  Binds to its own promoter region and to the Rv1999c promoter region.  It displays strong affinity for cadmium ions, but can also bind zinc, manganese and nickel.  Expression increases the intracellular survival of recombinant M.  smegmatis in murine macrophage cell line and increases its tolerance to cadmium ions.
What are the official names of this protein?
Transcriptional regulator Rv3488.
Protein: PCKA_SHEPA
Sequence: MADGSNREYLNLSTGQLVELALARGEGQLTANGALVAKTGERSGRSPNDRFIVKEPSSEADIEWGPVNKPFKADAFTALWNRVEAFLADKDTFVSNLEVGASKEHYQPVKVTTQYAWHQLFARNLFIVPEEFNAADKPVWQIINAPGFECVPERDGTHSDATVIINFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAKGVLPMHCSANVGADGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVVTDENRVPDYTNSSLTENTRAAYPLEHIAQRKLDNCGAEPHAVVFLTCDVSGVLPPVSKLTKEQAAYHFLSGYTAKVGSTEMGSTAAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGIGKRFDIPTTRAIVDAIVSGELKDVETEYLEKLNLHVPVAIPGVDSKLLNPINTWEDKVQYAEFAQHLADSFKANFEKYQVPDSIKNAGPNA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_FRATW
Sequence: MENKKVIVGISGGVDSSVSALLLKQQGYDVTGVFMKNWEEDDTDEFCSAEQDIADAQAVCDSIGIPFKKINFAAEYWDNVFEHFLIKYKAGRTPNPDILCNKEIKFKAFLSYVHLLGGDYIATGHYAQTRLAADGSVQLVKGLDDNKDQTYFLYTLGQEQLRQTIFPIGNIEKSKVREIAKENNLVTFDKKDSTGICFIGERKFKEFLSKYLPAQKGEIHDENGIKIGMHDGLMYYTIGQRQGLGIGGVKDRPEVPWFAAKKDLENNVLIAVQGHDHPLLFKQSLQAIELSWVAGMAPADKFRCAAKVRYRQKDQSCEVEVNQDGSVNVTFDQPQRAITPGQSVVFYIDDVCLGGGVII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBH_THET8
Sequence: AAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRKRKARTGVKPGTKEKIKIPATQYPAFKPGKALKDKVKK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU, DNA-binding protein II, TL29.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL20A_SCHPO
Sequence: MALKEYQVVGRKVPTEHEPVPKLFRMRLFAPNESVAKSRYWYFLKMINKVKKATGEIVAINEISEPKPLKAKVFGIWIRYDSRSGTHNMYKEFRDTTRVGAVEAMYADMAARHRARFRSIRILKVVEVEKKEDVRRNYVKQLLNPHLKFPLPHRRTGVVGLAGKKVFAPHRPSTFY
What are the official names of this protein?
60S ribosomal protein L20-A, YL17.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: FOLD_ACIET
Sequence: MTAQLIDGNALSRQLRTEVAARTAALKSRGITPGLAVVLVGDNPASQVYVRNKVKACEDVGFHSVLEKYDASMSEEQLLARVQALNNDPSIHGILVQLPLPKHIDDHKVIEAISPLKDVDGFHVASAGALMVGQVGFKACTPYGCMKMLESIGMKDLRGKHAVVIGRSNIVGKPMAMMLLAANATVTVCHSGTADLAAMTRQADVVVAAVGKRNVLTADMVKPGAVVIDVGMNRNDEGKLCGDVDFEGVKQVAGYITPVPGGVGPMTITMLLVNTLEAAERL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL30_BEII9
Sequence: MTTSTNRITIEQVKSPIGRPGSQKATLIGLGLNKIGRRSSLEDSPAVRGMIAKVAHLIRVIDGQ
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y2469_ACIBC
Sequence: MLALISPAKTLDYETALPTDEFTQPRLLEHSAQLIDVCRKLSASEIASLMSVSEKIATLNADRFRDWKPEFDFSNARQAIYAFKGDVYTGLDAYHLKDKDIDFAQQHLRMLSGLYGLLRPLDLMMPYRLEMGTKLKNTRGHNLYEFWDDIITNRINEDLAAIKSELLVNLASDEYYKSVNEKKIKAEIVKPVFLDQKNGKYKVISFYAKKARGLMARFIIENQLNKAEDIKAFNTEGYYFDADNSSAKELVFKRDEQ
What are the official names of this protein?
UPF0246 protein ACICU_02469.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RNH2_BURM9
Sequence: MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAYALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_ACIAC
Sequence: MSSIHSTAIVDPGAELDSSVTVGPYAVIGPKVRIGAGTSVGPHCVIEGRTTIGRDNRIFQFASLGAIPQDKKYAGEDTCLEIGDRNTIREFCTFNLGVPGAGGVTRVGDDNWIMAYCHIAHDCLVGNHTTLSNNTTLAGHVELGDWVTVGGLVGIHQFVKIGAHAMVGFASAVSQDVPPFMLVDGNPMGVRGFNIVGLKRRGFSADRLAAVKQMHRLLYRQGLTLEAAAKAIEELAAEHPEAAGDITLLRDFIVSSTRGIAR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACOHC_CHICK
Sequence: MSNPFVQIVEPLDAKEPVKKFFNLSKLEDVRYARLPFSIRVLLEAAIRNCDEFLVKKQDVENILNWKVMQHKNVEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPICPADLVIDHSIQVDFNRRSDSLQKNQDLEFERNKERFEFLKWGSQAFKNMRIIPPGSGIIHQVNLEYLARVVMDQDGYYYPDSVVGTDSHTTMVDGLGVLGWGVGGIEAEAVMLGQPISMVLPEVVGYKLLGNPQPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAYFPVDDISIGYLVQTGRDKEKVLCTKKYLEAVGMLRDFKNSSQDPDFTQVVELDLHTVVPCCSGPKRPQDKVAVSDMKKDFETCLGAKQGFKGFQIAPDRHNSVIKFNFEGCDFELAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLTVKPYIKTSLSPGSGVVTYYLRESGVMSYLSQLGFDVVGYGCMTCIGNSGPLPDSVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTVRIDFEKEPLGISASGKKIFLKDIWPTRNEIQAVERQYVIPGMFKEVYQKIETVNEAWNALDAPSDKLYTWNPKSTYIKSPPFFDGLTLALQTPKTIEDAYVLLNFGDSVTTDHISPAGNIARNSPAARYLTSRGLTPREFNSYGSRRGNDAVMARGTFANIRLVNKFIDKQGPQTIHFPSGETLDVFDAAERYKQAGHPLIVLAGKEYGAGSSRDWAAKGPFLLGVKAVLAESYERIHRSNLVGMGVIPLQYLPGEDARTLGLTGRERYTIIIPENLKPQMNIQIKLDTGKTFHAIMRFDTDVELTYFHNGGILNYMIRKMAS
What is the function of this protein?
Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.
What are the official names of this protein?
Cytoplasmic aconitate hydratase, Aconitase, Citrate hydro-lyase, Iron-responsive element-binding protein 1, IRE-BP 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PEO1_CHICK
Sequence: MAAVPLRPCRASGRFLPLLRGGARSRGASPWAAGPGRVAQRRYKKDVLPEPGGAAPAVSVTEIRRYLRAQGIPFQDGYSCLHAPSLFGPELPPAAGPPFTLFIDKTTGSFLCTATLAEGGWQDLQAAVELRHRGVPAPGPDEGEREEEEEAEARRAREDARRIWERALPLGELLDEEETRATKAAFGIAPLADGTLKRFGVRYLRAAKALVFPWFAPRDAALRGLKLLVAEQRGDAVSYTEETLPRFDAYRNLFGLPLIGRRDAEVVLTGSELDALALHQATGVPCLALPRGATILPPALLPYLEQFRRVTLWLGDDLRSWEASKLFARKLNPKRCSLVQPGDLQPRPLEALNRGLNLTKILRAALPAGHKAIVSFRQLREEVFGELANSEQVAGVKWARFPELNKLLKGHRRGELTVFTGPTGSGKTTFISEYALDLCTQGVCTLWGSFEINNIRLAKIMLTQFATRRLEDQLELYDEWADRFEDLPLYFMTFHGQQNIKTVLDTMQHAVYMYDITHVVVDNLQFMMGHEQLSADRLAAQDFIVGAFRKFATDNTCHITLVIHPRKEDDEKELQTASIFGSAKASQEADNVLILQDRKLTTGPGKRYLQVSKNRFDGDVGVFPLEFSKASLTFSSYGKSKAKLKKVKEEKGPSPKKGPSGGVGGSSKP
What is the function of this protein?
Mitochondrial helicase involved in mtDNA replication and repair.  Might have a role in mtDNA repair.  Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB.  Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate.  Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand.  In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities.
What are the official names of this protein?
Twinkle mtDNA helicase, Progressive external ophthalmoplegia 1 protein homolog, Twinkle protein, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Note=Colocalizes with mtDNA in mitochondrial nucleoids, a nucleoproteins complex consisting of a number of copies of proteins associated with mtDNA, probably involved in mtDNA maintenance and expression.
Protein: HTPG_SHEB9
Sequence: MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGNFTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKATALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHLTEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTSRLTDTPACVVAGEGEMSTQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.