PharMolix/UniProtQA huggingface dataset:
Protein: SUMF2_BOVIN
Sequence: MGISLSPLLTVLSLLSGRWLELGNGQTVNMVQLPGGRFQMGTDSPDGRDGEGPVREVTVKPFAIDIFPVTNKDFREFVREKKYRTEAEVFGWSFVFEDLVSDELRNKATQRMQSLLWWLPVERAFWRQPAGPGSGIREKLEFPVVHVSWNDARAYCAWRGKRLPTEEEWEFAARGGLKGQVYPWGNKFQPNRTNLWQGKFPKGDKAEDGFHGVSPVNAFPPQNDYGLYDLVGNVWEWTASQYQAADQDMRVLRGASWIDTADGSANHRARVTTRMGNTPDSASDNLGFRCASGAGRPPGEL
What is the function of this protein?
Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form.  Inhibits the activation of sulfatases by SUMF1.
What are the official names of this protein?
Inactive C-alpha-formylglycine-generating enzyme 2, Sulfatase-modifying factor 2.
What is the protein family that this protein belongs to?
Belongs to the sulfatase-modifying factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS4_DESVH
Sequence: MAKYTDAKCRQCRREGTKLFLKGDRCFTDKCAFDRRPYAPGQHGRARKKVSDYAVQLREKQKVRRMYGILEQQFHAYFTKADMAKGVTGANLLSLLERRLDNVIYRLGFANSRNQARQLVRHGIFTLNGRKVNIPSLQVRIGDTIEVPEKSRKIPVLAEAQEVIARRGCPAWLEADGANFRGVVKALPQREDIQFPINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ISPF_NEIM0
Sequence: MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: EX7L_CAMJD
Sequence: MTVSELNLKVKALLESYFENIILSGEISKITLHGSGHWYFDLKDEKSSISCAMFKGANLKVGFKPAVGDFLELCGSVSLYAESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIQALRKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVSDFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLIQLWNHKMQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQISQKEAKIL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D103A_PONPY
Sequence: MRIHYLLFALLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
What is the function of this protein?
Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Beta-defensin 103A, Defensin, beta 103, Defensin, beta 103A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_LACSA
Sequence: MKNVTDSFVSLGHWPSAGSFGFNTDILATNLINLSVVLGVLIFFGKGVLSDLLDNRKQRILNTIRNSEELREGAIEQLEKARARLRKVEIEADQFRVNGYSEIEREKLNLIDSTYKTLEQLENYKNETINFEQQKASNQVRQRVFQQALQGALGTLNSCLNSELHLRTISANIGILGAMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL17_LATSS
Sequence: MSYRKLGRTSSQRKAMLRDLTTDLIINERIVTTEARAKEIRKTTEKMITLGKRGDLHARRQAAAFVRNEVADIREEDEAVIVQSALQKLFSDIAPRYAERNGGYTRILKTAPRRGDGALMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CH601_PROMS
Sequence: MAKQLNFSNESREALEKGVNFVANAVKVTIGPKAKNVVIEKKFGSPDIVRDGSTVAKEIEIENPIANLGAKLIEQVASKTKESAGDGTTTATILTQKMVQEGLKNIASGANPMELKKGMEAGLAFVLEKLSSKSISLSGSDIQKVATVSAGGDEEIGSIISKAMDIVTSDGVITVEESQSLETELDITEGMSFDRGYSSPYFVTDQERQVCELENPKILITDQKISTLVDLVPILEEIQKAGSPFLILAEDIEGEALTTLVLNKNSGVLNVASVRAPLFGERRKAALEDIAILTGAKLISEDKSMTLDKVSINDLGKAKKITITKDKTTIVAFEDTKDLVEARVEKLKREVNITESEYDQDKINERIAKLAGGVALIKVGAATETEMKYKKLRIEDSLNATKAAIEEGVVSGGGQTLIEISDDLLNLSETSSDDLRTGINIVKEALLEPTKQIAKNAGFNGDVVVAEIQRLNKGFNANSGQYEDLKDSGILDPTKVIRLALQDSVSIAAMLLTTEVAMADIPEPEAAAPGGPGGDPMGGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SHIDS
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPLGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPEAPREGVVVPPVPDQEPEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSS_RAT
Sequence: MTEGTCLRRRGGPYKTEPATDLTRWRLHNELGRQRWTYYQAEEDPGREQTGLEAHSLGLDTTSYFKNLPKAQTAHEGALNGVTFYAKLQAEDGHWAGDYGGPLFLLPGLLITCHIAHIPLPAGYREEMVRYLRSVQLPDGGWGLHIEDKSTVFGTALSYVSLRILGIGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGLLNLYERFHSTSLRKWAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQTWDTSFAVQALLEAGAHRRPEFLPCLQKAHEFLRLSQVPDNNPDYQKYYRHMHKGGFPFSTLDCGWIVADCTAEALKAVLLLQERCPSITEHVPRERLYDAVAVLLSMRNSDGGFATYETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFREYFPDHRATESRETLNQGLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHIYQNRTACAEVAQACHFLLSRQMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGLMAVRHPDISAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWALGRFSSLYPDNTLAGHI
What is the function of this protein?
Key enzyme in the cholesterol biosynthesis pathway.  Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:7568116).  Through the production of lanosterol may regulate lens protein aggregation and increase transparency (By similarity).
What are the official names of this protein?
Lanosterol synthase, 2,3-epoxysqualene--lanosterol cyclase, Oxidosqualene--lanosterol cyclase, OSC.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: GLND_SODGM
Sequence: MQGDPMPDQILQFTHPPVPRQPPVKPSSPLTWPDDALNRPFLKERLDEFQRWLADAFDAGETAEILVDARTLYIDQLLRQLWHYHGLAHAPHTALVAVGGYGRGELHPLSDIDVLVLSQAPLTPPQQQHISELLTLLWDLKLEVGHSVRSIAECLEEGRADLTVATNLIESRLICGDLALFLTLQKQVFSDDFWPSRAFFPAKLAEQQERHSRYHGTSYNLEPDIKSSPGGLRDIHTLLWVAHRHFGATSMDEMVGFGFITRAERDELNECQSFLWRTRFALHLVLNRYDNRLLFDRQQNVAQLLRYQGEGNLPVERMMKDFFRVTRRVSELNQMLLQLFDEAILALAPDEKPQPLDDEFQLRGNLIDLRDETLFSRQPEAILLLFWQMVRNRHIEGIYSATLRQLRYARRHLKAPLCTSPEARTLFMRILHQPGAVKHALLPMHRHSVLWAYMPQWSNIVGQMQFDLFHAYTVDEHTIRVLLKLESFADESQRPYHPLCVELFPRLSQRHLLLVAALFHDIAKGRGGDHSQLGARDVLEFAALHDLPAEDAQLVAWLVESHLVMSVTAQRRDIQEPDVLVQFAGEMQSESRLHYLLCLTVADICATNETLWNSWKQSLLRELFFATEKQLRRGIHVSPDVRERVRHNRRQSLVLLRMEGIDEQRLQEIWSRCRADYFLRHTPNQLAWHARHMVLHDHDEPLVLISPQATRGGTEIFIHNQDRPYLFAAVTGELDRRNLSVHDAQIFTNRDGMAMDTFVVLEPDGSPLSPDRHPVIRQALLQILLPGDYRHPRVRRPSSKLRHFNVDTSVVFLPSPTERRSYLELTALDQPGLLARVSEVFVDLGISLHGARISTIGERVEDLFILADGDRRALSRAMQAEVRRRLTEALNPNDKV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RL16_SALNS
Sequence: MLQPKRTKFRKMHKGRNRGLAAGADVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: M2DH_ASPFU
Sequence: MAPLKLNSRNLSQIAAAGGALVKIPTYQRGRAVKEGIVHIGVGGFHRAHLAVYIDQLMQKHGVNDYAICGVGLQPFDSAMRDALASQDHLYTLIERSAKGSFAHVIGSINSYLFAPDNREAVIAKMAHPDTKIVSLTITESGYYYNENTHELQSEHPDIQFDLDPANEKAPRTTFGFLYAGLTRRYQQGLKPFTVMSCDNMQKNGSITRHMLESFARLRNPEVAEWIAEEGAFPNAMVDRITPQTSETDKTALAEKFGIVDSWPVVTEPFTQWVIEDQFSDGRPPFEKVGVQVVKDVHAVEQFEKHKLRLLNGSHSALGYPGQLAGFQYVHEVMANPLFRKFVWQMMQEEVKPLLPEIPGVDIDEYCNTLIERFTNPTIMDQLPRICLNASGKIPQFIMPSIAEAIWETGPFRRLCFVAAAWFHYIKGVDDRGKPFEVVDPMREELQAKARAGGNDPSELLSIKSLFGDDLRNDERFLREITTAMNDIARDGIMKTLPKYIN
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.  Has a preference for NADH over NADPH.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: CU95_CONCL
Sequence: MNCYLILTVALLLTSAMTGTTTAGQLNTKGVTLREDDRTFPCSSGLCACLPLDSYSYICLSPSSSTANCENDECISEDDW
What are the official names of this protein?
Conotoxin Cl9.5, Cal9.2f.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_STRMU
Sequence: MTDKKTLKDLRNRSSVYDSMVKSPNRAMLRATGMQDEDFEKPIVGVISTWAENTPCNIHLHDFGKLAKVGVKEAGAWPVQFGTITVSDGIAMGTQGMRFSLTSRDIIADSIEAAMGGHNADAFVAIGGCDKNMPGSVIAMANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGVGHWNHGDMTKEEVKALECNACPGPGGCGGMYTANTMATAIEVLGLSLPGSSSHPAESAEKKADIEEAGRAVVKMLEMGLKPSDILTREAFEDAITVTMALGGSTNSTLHLLAIAHAANVELTLDDFNTFQEKVPHLADLKPSGQYVFQDLYKVGGVPAVMKYLLKNGFLHGDRITCTGKTVAENLKAFDDLTPGQKVIMPLENPKREDGPLIILHGNLAPDGAVAKVSGVKVRRHVGPAKVFNSEEEAIEAVLNDDIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGEKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLQTGDIVTIDQDTKELHFDISDEELKHRQETIELPPLYSRGILGKYAHIVSSASRGAVTDFWKPEETGKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RUVA_ALKEH
Sequence: MIGRLHGTVAERHPPALLLDVGGVGYELEAPMSTFYALPAGDQAVTLWTHLAVRDDGQALYGFASRAERDLFRVLIRISGVGPKLALALLSGMNAEGLQRCIEREDVATLTRLPGVGRKTAQRLIVELRDRLDGLLPAASGGVPARTGSGEQLDAPAGPQGSREDAVSALVALGYKPAEAGRLVNAVPGANDLPSEELIRRALQAAVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ENGB_CAMJR
Sequence: MIISAKFITSLVKFDENLSSNFSEVAFLGRSNVGKSSLINSLCKQKNLAKSSATPGKTQLINFFEVICKRNEEKFNINFIDLPGFGYAKVSKNLKEIWNQNLDEFLKLRTSIKLFIHLIDSRHTHLEIDVNLNDYLKRFLRPDQKILKVFTKCDKLNQSEKAKLKNEFKDSILVSNLNKFGLDSLEDIIINQTLGLDK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS16_RHOPT
Sequence: MSVVIRLARAGTKKRPFYHVVVADSRFPRDGRFIERLGYFNPLMAKDNEARLKLDLDKVKDWLAKGAQPSDRVARFLDTAGVRKREARNNPEKAVPRKERKAADGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: AROB_STRP7
Sequence: MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_THET2
Sequence: MGHEAKHPIIIGITGNIGSGKSTVAALLRSWGYPVLDLDALAARARENKEEELKRLFPEAVVGGRLDRRALARLVFSDPERLKALEAVVHPEVRRLLMEELSRLEAPLVFLEIPLLFEKGWEGRLHGTLLVAAPLEERVRRVMARSGLSREEVLARERAQMPEEEKRKRATWVLENTGSLEDLERALKAVLAELTGGAKGGRG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_PSEPG
Sequence: MRVILLGAPGAGKGTQAKFITEKFGIPQISTGDMLRAAVKAGTPLGLELKKVMDAGQLVSDELIISLVKERIAQPDCANGCLFDGFPRTIPQAEAMVAAGVDIDAVVEIAVDDEEIVGRMAGRRVHLASGRTYHIQYNPPKVEGKDDVTGEDLIQRDDDKEETVRHRLSVYHTQTKPLVDFYQKLSAANAGKPKYSHIEGVGSVDAITAKVLAALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPR_YEAST
Sequence: MFDQLAVFTPQGQVLYQYNCLGKKFSEIQINSFISQLITSPVTRKESVANANTDGFDFNLLTINSEHKNSPSFNALFYLNKQPELYFVVTFAEQTLELNQETQQTLALVLKLWNSLHLSESILKNRQGQNEKNKHNYVDILQGIEDDLKKFEQYFRIKYEESIKQDHINPDNFTKNGSVPQSHNKNTKKKLRDTKGKKQSTGNVGSGRKWGRDGGMLDEMNHEDAAKLDFSSSNSHNSSQVALDSTINKDSFGDRTEGGDFLIKEIDDLLSSHKDEITSGNEAKNSGYVSTAFGFLQKHVLGNKTINESDLKSVLEKLTQQLITKNVAPEAADYLTQQVSHDLVGSKTANWTSVENTARESLTKALTQILTPGVSVDLLREIQSKRSKKDEEGKCDPYVFSIVGVNGVGKSTNLSKLAFWLLQNNFKVLIVACDTFRSGAVEQLRVHVENLAQLMDDSHVRGSKNKRGKTGNDYVELFEAGYGGSDLVTKIAKQAIKYSRDQNFDIVLMDTAGRRHNDPTLMSPLKSFADQAKPDKIIMVGEALVGTDSVQQAKNFNDAFGKGRNLDFFIISKCDTVGEMLGTMVNMVYATGIPILFVGVGQTYTDLRTLSVKWAVNTLMS
What is the function of this protein?
Component of the SRP (signal recognition particle) receptor (SR).  Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.  GTP hydrolysis may enhance the fidelity of and provide unidirectionality to the targeting reaction.  It is important but not essential for cell growth.  May be directly involved in mitochondrial protein import.
What are the official names of this protein?
Signal recognition particle receptor subunit alpha homolog, SR-alpha, Docking protein alpha, DP-alpha.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family.
Protein: RL35_LARHH
Sequence: MPKMKTKSSAKKRLKVLGNGGVKRSMAFKRHILTKKTTKTKRQLRGTVMVHETNMASVRAMMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DEF1_DERVA
Sequence: MRGLCICLVFLLVCGLVSATAAAPAESEVAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
What is the function of this protein?
Antibacterial activity against Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Defensin, Varisin A1.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
Protein: FAP20_BOVIN
Sequence: MEATRRSRLSLSRRRPPLGVRPRSNTAGSLPDGGECAKLWTELLRTASADLNVDGELPPLPAFPDQEPRRSPERPPPETFTVGTETFFWTPFPAPSPGRGGNSGGSDLVLSAVRGRTGSPQQYAAPELRGTPSAEEQPSEEQPSQRQSSVDGAMTLQSCPMCQVDFAPGLAQLDIDGHLAQCLADSTDDIEW
What is the function of this protein?
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair.  Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex.  Promotes translesion synthesis via interaction with REV1 (By similarity).
What are the official names of this protein?
Fanconi anemia core complex-associated protein 20, FANCA-associated protein of 20 kDa, Fanconi anemia-associated protein of 20 kDa.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8.
Protein: FUCM_HAEIE
Sequence: MLKGIHPALSPELLKTLAEMGHGDEIVLADTHFPAHSLHKNVIRADGISIDILLEAITPLFEFDAYVDAPLLMMKAVEGDSLDPNVETRYLNAIESAVGFTPNLTCLERFDFYTRAKQAYAVVVSGEIAKYGNIIIKKGVTPIL
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_CLOPE
Sequence: MQSILKPITNLFTMIFQAIHGFVASLDIFGVGAGYVITIFLLTLLVRLILLPLNIKQTRSQQKMQEIQPEIAKLQKKYKNNPEKAQQEMMKLYKENNVNPMSGCLPLLIQMPILFALYYVFTGLTELQGVSFLWLGDLWAPDRTFILPILSAATTYLSSLLMTKFTQSQAGGAPGGMNMNTMNIVMAGMMGVMSIQFPSMLVLYWVIGNLIQMVQTYFIVVLPSKKRAKEKEQYKDIK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCA_PHOPR
Sequence: MSLNFLEFEQPIAELEAKIEALRDVSRRDESASVDLDKEIEQLEKKSLELTKKIFSNLGAWQVAQLARHPERPYVFDYIEHIFTEFDALAGDRAFADDKALVGGIARLDGRPVMVIGHQKGRGTKEKVFRNFGMPKPEGYRKALRLMKMAERFKMPIITFIDTAGAYPGVGAEERGQSEAIATNLKAMAGLTVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSNKAPQAAEAMGLTAGRLKELELIDSIIEEPLGGAHRDLEAISASLKATLVANLAELEALDTDELLERRYQRLMSYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_VIBC1
Sequence: MTGLERQLTEMLEAPVEATGYELVGLEFIRAGAHSTLRIYIDHENGINVDACAEVSHQVSAVLDVEDPISVAYSLEVSSPGLERPLFKAAHYEQFIGHEVSIVLKMAVANRRKWKGIIHSVDGETIAVTCEGQQEEFALSNISKANLIPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRT1_CAEEL
Sequence: MNPRLRVYIFAGIFLFIALIILIKIFFEEEKFDVLVVSLDSKEKTSKECLSNLQSVSIPVPALIIDKTVLKAIYQENCEHIFERKIKIGIDKRNWKLIANHNESSIFECIRMENKTSNDYLQFDTQPARAVLKNFNTFSIGNLHIPSNIPLFLKMWERSEIRGCLNLIVHRNMTKSQQFNHGKEAAEKLAEFRDVLLTFNMFAFLNGGTLLGWYRECGFIPHTADIDLAMFAEDFHPEITHFLLSRTSSFQLLRSLGMLNDSYELTVTPKTGYIVNMDLFLMYKDVHKNGSVINWVGGASNDIKYKYTYPAYDPWCAADLHGHLFWVTCSPQKMLVFEYGNLWYEDHPSSQYDWRSTAKNVRTNGLWSDVELKNVSKLY
What are the official names of this protein?
Uncharacterized protein T07A5.1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.