PharMolix/UniProtQA huggingface dataset:
Protein: TIM10_RAT
Sequence: MDPLRAQQLAAELEVEMMADMYNRMTSACHRKCVPPHYKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRVQQSSGPA
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: B2SN1_SYLSP
Sequence: MFTMKKPLLFLFFLGTISLSFCEEERGADEDDEVEMTEEEKRGLRDKIKNVAIDVAKGAGTGVLKALLCQLDKSC
What is the function of this protein?
Antimicrobial peptide.  Active against some Gram-negative and a variety of Gram-positive bacterial strains.  Active against fungus C. glabrata 090902 but not against C. albicans ATCC 10231.  Shows hemolytic activity against human erythrocytes.
What are the official names of this protein?
Brevinin-2SN1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD11_MOUSE
Sequence: MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYSKAKKLT
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  In the complex, PSMD11 is required for proteasome assembly.  Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit p44.5.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
Protein: ANR54_DANRE
Sequence: MDGSSPLLAAAGSDGDRSSSEGEYTLAGGPSAGDTEKREGESPMEAAGAGTVGFSISRLDTLSALRLNRTRPAADTELRYLHLLWKPGELLQAGRSTPGKITSSRVRRLARARRNMGPIGKDLHAVKRLREAANSNDIDTVRRLLEDDTDPCAADDKGRTALHFSSCNGNETIVQLLLSYGADPNQRDSLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLARSKLNILQEGDSRSLETLRGEVTQIIQMLREYLNIMGQSEEREKLEHISTQLQNTRTREQVDEVTDLLASFTSLSIQMQNMGDR
What is the function of this protein?
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 54.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Midbody. Note=Shuttles between nucleus and cytoplasm during the cell cycle.
Protein: BSAZ_BURM7
Sequence: MAEKTEKPTAKKLRDAAKKGQTFKARDIVALIVIATGALAAPALVDLTRIAAEFVRIASTGAQSNPGAYAFAWAKLFLRIAAPFVLLCAAAGALPSLVQSRFTLAVESIRFDLTALDPVKGMKRLFSWRSAKDAVKALLYVGVFALTVRVFADLYHADVFGLFRARPALLGHMWIVLTVRLVLLFLLCALPVLILDAAVEYFLYHRELKMDKHEVKQEYKESEGNHEIKSKRREIHQELLSEEIKANVEQSDFIVANPTHIAIGVYVNPDIVPIPFVSVRETNARALAVIRHAEACGVPVVRNVALARSIYRNSPRRYSFVSHDDIDGVMRVLIWLGEVEAANRGGPPPETRAPTSAEPQARDGVAPLGDACADNAFPDDAPPGAAAPNAGSPDSPAPDGGAPARTGDQNA
What is the function of this protein?
Part of the bsa type III secretion system, is involved in the intracellular replication of invading bacteria inside the host cell.  Probably necessary for the lysis of the vacuole membrane and escape into the host cell cytoplasm (By similarity).
What are the official names of this protein?
Secretion apparatus protein BsaZ.
What is the protein family that this protein belongs to?
Belongs to the type III secretion exporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1601_NOSS1
Sequence: MTSLFPHQKAKALKPNSRRPAKELCSECGLCDTYYIHYVKEACAFITQQIDTLEEQAHQRSRNLDNPDELYFGVHQDMIAAKKQQPIAGAQWTGIVSSIAIEMLNHGLVEGVVCVQNSKEDRFQPMPVIARTPEEILAARVNKPTLSPNLSILEQVEKSGMKRLLVIGVGCQIQALRAVEKKLGLEKLYVLGTPCVDNVTRAGLQKFLETTSRSPETVVHYEFMQDFRIHFKHEDGSIEKVPFFGLKTNQLKDVFAPSCMSCFDYVNSLADLVVGYMGAPFGWQWILVRNDTGKEMLDLVQNQLDTQPVMSEGNRQEAVQQGISAYDKGVTLPMWVAKIMGVVIDKIGPKGLEYARFSIDSHFTRNYLFVKRNHPEKLAAHVPEFAKRIVGQYKLPE
What are the official names of this protein?
Uncharacterized protein all1601.
Protein: LST2_CAEEL
Sequence: MQSFRKIWNKPRPDDWMPLARFYYADSALNDIASELDSFDGRRDPDRCNALVTRLRVAQDRVLHIITEMLIHLYPREQDRACRDFRVKFPDEILHDTLPGQLWFGAECLSAGSNIIDHETESDLIRPLAKDVTKQLDFLRDLLKNQSLRDPSAYNPVIKENLLKFDKLFAEFEYQYVSAMVPVKSVKEHDSQLDVAVLFSEVLSLALVKDLITQDLIDYCDPSVMIAIPRLGIVWGLLVYSNGALNVDVPAENLSEMFRPFYSLLVKIRNLLRILTPTELTKLETVLCKGESAVPEDTSSTLTMSDFRTNATDEEKAKNNQRVWMCDMPSDSTSSLDSSVQDSSSETTSLASSALASPHSGSEENVSQIENEEGDDEAIGTNSNSSNEVTESPETIEEPDNVDMEESSESEVDTHIDETRNESDDEITDDVQASDVLQVETKKCKSSRLLEQKKFDKSVKTIIPMQTDPRSQIDPKNLRSRFRSSEDLVHRLFVCIAGVADQLQTNYSSEIRKVLKLILQPSEIIPVYEVVNAQVANSQTEGEETGVEAQETLPLPAFMGVRWVPDEDCEQCTACSMPFNFVRRRHHCRNCGRIFCHKCSCNTISIPEHGYDRKVRVCNLCYVHRLNSFGCNEPMSQVNENGATVPSVTEQQSAQTASASS
What is the function of this protein?
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
What are the official names of this protein?
Lateral signaling target protein 2.
What is the protein family that this protein belongs to?
Belongs to the lst-2 family.
Protein: ATF1B_DANRE
Sequence: MARFLNSNIRKFLTTQIRMSSDQLGELGKGAGKGGGGGGAVRQAGGAFGKKQAAEEEMYFKRKEQEQLSALRRHHQEEIDHHKKEIERLQHEITRHESKIKKLKHDD
What is the function of this protein?
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix.  Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity).  Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity).
What are the official names of this protein?
ATPase inhibitor B, mitochondrial, ATP synthase F1 subunit epsilon B, Inhibitor of F(1)F(o)-ATPase B, IF(1) B, IF1 B.
What is the protein family that this protein belongs to?
Belongs to the ATPase inhibitor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: WDR89_PONAB
Sequence: MEKIEEQFANLHIVKCSLGTKEPTYLLGIDTSKTVQAGKENLVAVLCSNGSIRIYDKERLSVLREFSGYPGLLNGVRFANSCDSVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINCNDHIICAGTEKVDDDALLVFWDARMNSQDLSTTKDPLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEEDALVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHLDTDEPVTRLNIQDVREVVNMKEDALDYLIGGLYHEKTDTLHVIGGTNKGRIHLMNCSVSGLTHVTSLQGGHAATVRSFCWNVQDDSLLTGGEDAQLLLWKPGAIEKTFTKKESMKIASSVHQRVRVHSNDSYKRRKKQ
What are the official names of this protein?
WD repeat-containing protein 89.
Protein: YBEY_AGARV
Sequence: MSFFIEKEVECNFNFDYEKVAEAVVSASLEHENFPYEAEVNLTLTDNEGIHAINKEYRQIDRPTDVLSFPMLSYETPGDFSFLSDENEDDFNPDTGEVMLGDIIISVDKVKEQAVEYGHSEKREFAFLITHSMLHLFGYDHMEADEAAVMEEHQRKILDALGITR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_BACFR
Sequence: MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASISEFKGELGDLTVHVSLGKDTITISDRGIGLTAEEIDKYINQIAFSGANDFLEKYKNDANAIIGHFGLGFYSAFMVSKKVEIITKSYKEGAQAVKWTCDGSPEFTLEEVEKADRGTDIVLYIDDDCKEFLEESRISALLKKYCSFLPVPIAFGKKKEWKDGKQVETAEDNVINDTIPLWTKKPSELSDEDYKKFYRELYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIDLNKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVLDSPDIPLNVSRSYLQSDSNVKKISTYISKKVSDRLQSIFKNDRAQFEEKWNDLKIFINYGMLTQEDFYDKAQKFALFTDTDGKYYTFEEYQTLIKDNQTDKDKNLIYLYANNKDEQFAYIEAAKNKGYNVLLMDGQLDVAMVSMLEQKLEKSRFTRVDSDVVDNLIVKEDKKSDVLEASKQEALSAAFKSQLPKMEKVEFNVMTQALGENGSPVMITQSEYMRRMKEMANIQAGMSFYGEMPDMFNLVLNSDHKLVKEVLADEEKECSAAIAPIQTELEDVTKRRDALKKKQEGKKDEDIPTVEKDELNDLDKKWDELKQQKDSIFAGYAGKNKVVRQLIDLALLQNNMLKGEALNNFVKRSIELI
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein htpG, Heat shock protein htpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1669_STAAS
Sequence: MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
What are the official names of this protein?
UPF0354 protein SAS1669.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: PSB27_THEVB
Sequence: MKRFWAMVCALFLSVSLLLTSCANVPTGLTGNFREDTLALISSLREAIALPENDPNKKAAQAEARKKLNDFFALYRRDDSLRSLSSFMTMQTALNSLAGHYSSYPNRPLPEKLKARLEQEFKQVELALDREAKS
What is the function of this protein?
Plays a role in the repair and/or biogenesis of the calcium-manganese-oxide cluster on the lumenal face of the thylakoid membrane.  Its presence in a photosystem II (PSII) preparation prevents binding of other extrinsic subunits PsbO, PsbU and PsbV, and thus assembly of calcium-manganese-oxide cluster.  Psb27-containing complexes lack oxygen evolving activity and an oxidizable calcium-manganese-oxide cluster, but have a normal reaction center.
What are the official names of this protein?
Photosystem II lipoprotein Psb27, Photosystem II 11 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the Psb27 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid- anchor; Lumenal side. Note=Associated with PSII on the lumenal side of the thylakoid membrane. Might also be associated with the cell's inner membrane.
Protein: VIAA_SALA4
Sequence: MLTLDTLNTMLAVSEEGMVEEMILALLASPQLVIFFEKFPRLKNAVTADLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILALLHRLHSPYTAQAKQLTESNSTFTPALHTLFLQRWRLSLVVQATTLNQQLLEEEREQLLSDVQERMTLSGQLEPTLAENDNAAGRLWDMSAGQLKRGDYQLIVKYGEFLAAQPELMQLAEQLGRSREAKSVPKKDAPMETFRTLVREPATVPEQVDGIQQGDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDVDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRVALADNRRCFIMLFSTDVVRYELSGPEGIEQAIRFLSQRFRGGTDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVSKVGELQRLHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: CAT_STAIN
Sequence: MTFNIIKLENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKKKGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWTESDNNFTSFYNNYKNDLFEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNSSFLLPIITIGKFYSENNKIYIPVALQLHHAVCDGYHASLFINEFQDIIKKVDDWI
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: CYSI_BORPD
Sequence: MQSTDNDLSQSPPKLSADEQLKAASDQLRGTILRSLADPLTGAVSDSDAKLLKFHGIYQQDDREQRDERRRQKLEPAYQFMIRVRLPGGVCSAAQWLKLDELARAYGGDSLRLTTRQTFQFHWVLKHNLQATLQGLHEVLLDTIAACGDDARGVMCTADPRLSALHAAVYDIARQASDHAIPRMRAYHEIWWGEQRVASSDAGPEEPFYGQTYLPRKFKIGFVIPPVNDIDVYAQDLGFIAIAGDDGALQGFNVAIGGGMGRTDQAPATYPRLADVIGFVPPEAVIATCDAVMGVQRDYGNRKDRARARFKYTIDEHGLDAVKAEIERRLGFALQPARPFRFDSNGDALGWQTGEDGRHHVTLFIQNGRLVNLPGLPLLEGLREIARVHTGSFRITPNQNVVIADIGDAERPRIEALLRQYQLEAGPSTSALRLNSMACVALPTCGLAMAESERYLPELVGKIEALLRTHGLEREPITIRMSGCPNGCSRPYIAEIGLTGRAPGKYNLYLGGGFHGQRLNRMVLENAAEAAILALLDTTLAHYARDRHEGEHFGDFAVRAGYVEAVTAGRDFNQRRAPGAGATAPHA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: YBEY_SPICI
Sequence: MKDDFVIYNETDFYIKPYQDDFNAIFQKIKTLLAITEPLELSLIIVDAQEQLELNQKYRHKDYVADVITFALEEENKIDLFELTGLRSLGDIFICYEKALAQAAEYNHSPRREFAFLFTHGMLHILGYDHQTPADEEKMFNLQRKVLNDLQINRIPIK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAD_MOUSE
Sequence: MTLNGGSGASGSRGAGGRERDRRRGSTPWGPAPPLHRRSMPVDERDLQAALAPGSLATTAAGTRTQGQRLDWPEGSSDSLSSGGSGSEEGVYKVLLLGAPGVGKSALARIFGGIEDGPEAEAAGHTYDRSITVDGEEASLLVYDIWEEDGGCWLPGHCMAMGDAYVIVYSITDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEDNARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
What is the function of this protein?
May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (PubMed:36424916).  May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-dependent L-type Ca(2+) currents (PubMed:17525370).  Regulates voltage-gated L-type calcium channel subunit alpha-1C trafficking to the cell membrane (PubMed:17525370).  Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway (PubMed:18056528).  Inhibits phosphorylation and activation of CAMK2D (By similarity).
What are the official names of this protein?
GTP-binding protein RAD.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RGK family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: TYSY_CERS5
Sequence: MAHPEQHYLDLLAQVLARGDRRVDRTGVGTLSLFGAMLRFDLSKGAAPILTTKKVYWKTAVKEMLWFLTGGTNIRPLLQQNVRIWTDWPLAAYRRATGEEIGQAEFEARIVADEGFAARWGDLGPVYGKQWRRWLGPDGREHDQIAGLIETLRTNPASRRMLFHAWNVAEVGQMALPPCHMVYQYHVTSDGRLNALLYQRSVDLLLGAPFNFVGAAALQLMIAQQADLLPGELVWVGGDTHLYLNHLEQAREQISRAPRDWPRMQLVRRAESIDDYRIEDFAVEGYESHPAIAAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG155_CAMPS
Sequence: MNSLSIFFIVVATAAVCLLFIQGYSIYENYGNIKEFNATHAALEYSKSIGGTPALDRRVQDVNDTISDVKQKWRCVAYPGNGFVSASIFGFQAEVGPNNTRSIRKFNTMAQCIDFTFSDVINIDIYNPCVAPNINNVECQFLKSVL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein OPG155, Protein CMP145.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG155 protein family.
Protein: RECA_CHLTB
Sequence: MSVPDRKRALEAAIAYIEKQFGAGSIMSLGKHSSAHEISTIKTGALSLDLALGIGGVPKGRIVEIFGPESSGKTTLATHIVANAQKMGGVAAYIDAEHALDPNYAALIGANINDLMISQPDCGEDALSIAELLARSGAVDVIVIDSVAALVPKSELEGEIGDVHVGLQARMMSQALRKLTATLARTNTCAIFINQIREKIGVSFGNPETTTGGRALKFYSSIRIDIRRIGSIKGGENFDIGNRIKVKVAKNKLAPPFRTAEFDILFNEGISSAGCIIDLAVEKNIIDKKGSWFNYQDRKLGQGREAVREELKRNKELFHELERRIYESVQASQAPAAACVDSESREVAEAAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_PARDP
Sequence: MPVFYGTRVESPLMLGTAQYPSPAIMAEAFRASRAGIATVSLRREGGAGQDFHRLIKDLGIPVLPNTAGCHSVREAVTTAQMARELFETPWLKLEVIRDDDTLCPDVIALVEAARVLSDDGFQVFPYCTEDLSVCGRLLDAGCQVLMPWGAPIGSGRGLNNPYGLRSLRAHFPDVPLVVDAGIGLPSHAAQAMELGYDAVLLNTAVAKAGDPVAMARAMALAIEAGQLAHGANPIEARDMAAPSTPLFGMAVLG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_MYCTA
Sequence: MNDSNDTSVAGGAAGADSRVLSADSALTERQRTILDVIRASVTSRGYPPSIREIGDAVGLTSTSSVAHQLRTLERKGYLRRDPNRPRAVNVRGADDAALPPVTEVAGSDALPEPTFVPVLGRIAAGGPILAEEAVEDVFPLPRELVGEGTLFLLKVIGDSMVEAAICDGDWVVVRQQNVADNGDIVAAMIDGEATVKTFKRAGGQVWLMPHNPAFDPIPGNDATVLGKVVTVIRKV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL23_SALTY
Sequence: MIREERLLKVLRAPHVSEKASTAMEKTNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: F90A7_HUMAN
Sequence: MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRSPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRNALLHMFSGKPPEKPLPNGKGSTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAVRPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELRAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Putative protein FAM90A7.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: CHM4B_CHICK
Sequence: MSGILGKLFGAGAGGKGAGKGPSPQEAIQRLRDTEEMLSKKQEFLEKKIEQELAAARKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIDKVDELMQDIAEQQELADEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSISIPSKPAKKKEEEEDDDMKELEAWAGNM
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein. Midbody.
Protein: DAPF2_NOSS1
Sequence: MKFYKYHALGNDYLVINPQDLKFPLTPEKIKIICHRNFGIGSDGILLGPLASTKAQFALRIFNPDGSEAEKSGNGLRIFSRYLWDMGLVDEKPFSIETAGGIVESAIKDAGKTVQVEMGKVSFWSRDIPVIGDDREVIQEKIFLDEGIFTFCAATIGNPHCVILLDDINSEVARNFGPIFEGYPLFPNRTNVQFMKVLDRSTIQIEIWERGAGYTLASGSSSSAAAATAHKLGLCDSKIIVKMPGGDILIQIKDDFHISMTDSVTKLAQGELSTEIFAIETVINI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase 2, DAP epimerase 2, PLP-independent amino acid racemase 2.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_PERSR
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, PerSu-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MGSA_CLOP1
Sequence: MKIALIAHDKKKEEMIELAKDFEDKLSKHILVATGTTGLKVMQNTSLDVKRCKSGPLGGDQEIGAMVANHDVDMVIFLRDPLTAQPHEPDISALLRLCDVYKVPLATNTESAKLIMADI
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RL35_BORPE
Sequence: MPKMKTKKSAAKRFKVRGSGSIKRGQAFKRHILTKKTTKNKRQLRGSAAVHETNVASVKAMMPFA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.