PharMolix/UniProtQA huggingface dataset:
Protein: BPT_METNO
Sequence: MTSHPRDAPQFYLTAPSPCPYLPGQYERKVFTHLVGRRARDLNEILTQGGFRRSQTIAYRPACETCRACISVRVIVGDFVPSASQRRVMRRNRDLVGQPQPNRPASEQYALFRRYLDARHGDGGMVDMTVLDYAMMVEDSHVETHLVVYRKRGPDTAINGRGVGAPIAICLTDVLSDGLSMVYSFYEPSEADRSLGTYMILDHIERARLLGLPYLYLGYWVEGSRKMDYKAKFGPQERLMPQGWVRVE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_EHRRW
Sequence: MHYNFKEVERDVQEKWDFTVNVKDVQCYVLEMFPYPSGNIHMGHLRNYTIGDVIARYKRACGLHVFHPIGWDAFGLPAENAALSYNISPQVWTRKNIDNMRSQLKSIGLSYNWDKEFATCDAEYYKYEQEFFLDFLKYGLAYRKESLVNWDPVDQTVLANEQVIDGRGWRSGAIIEKRKLSQWFLKITDFAAELLDDLKSLNQWPEKVKLMQERWIGKSEGVIIDFQIVGINEVLQVFTTSPHTLFGASFIAVSFDHPILKYVNDVQLIQLIDNFDRKDLIDESSINTVEKFGINSGLVARHPLLDVDLPIYVANFVLMNYGTGAVFCCPAHDQRDFDFAKKYSLPIRQVIFPEQNVDLEQEAYVGSGIMGCSGFLDGMTVDDAKKSMIEKLISLGICKKQVYYRLHDWGISRQRYWGCPIPIIYCKKCGIVPVDKKDLPITLPEDIDFTKSGNPLDNHPTWKYTKCPSCGADAKRETDTFDTFFESSWYFAAFCGIGKGIDKDVCNKLLPVDYYIGGIEHAVLHLLYSRFFCRALTRCGYFDVKEPFSSLITQGMVCHSTYLDKYGNYLFPEDGKKMIQEGKYVTVGRAEKMSKSKKNVVHLDDIIDKYGADSARLFILSDTPPERDIEWLDENIEGVSRYLNKLWKMIVDYDQLEQNFVCDNISSDTLEYRINVHKILNDITNDLEFYRFNCAVAKFRELSNVISEMIRLSINHHVVSEAIYILIRVVEPFIPHIAEKLWQIVGGQGMLCNQLWPKVDPQLLIKKNVNIVVQVNGKFIKAVSVPNDIDDDTLKSIALEVAQRRIGNSSVKNIYIIPGRVINIVITKSS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXD1_CHICK
Sequence: AFSLRTSFSTRQLTELEKEFHFSRYLSRARRLEVARSLRLRDAQVKVWFQNRRMKQKKRERERWPDP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D1, Homeobox protein CHOX-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTC_PSE14
Sequence: MTKKAIIPAGTTKPIAPFVPGSMADGVLYVSGTLPFDKDNNVVHVGDATAQTRHVLETIKSVVETAGGTMDDVTFNMIMIRDWADYAKVNEVYAEYFAGEKPARYCIQCGLVKPEALIEIASIAHIG
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: PRDX_ASCSU
Sequence: MSKAMIGKPAPEFTATAVVDGDFKSISLSDYKGKYVVLFFYPMDFTFVCPTEIIAFSEHVGEFKKLGVEVLAASTDSQFSHLAWINTPRKQGGLGEMKIPIISDNNHQISRDYGVLKEDDGIAYRGLFIIDPKGILRQITVNDLPVGRSVTETLRLVQAFQFVDKHGEVCPAGWTPGADTIKPGVKESKAYFEKH
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin, AsPrx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
Protein: PDXH_DEIRA
Sequence: MTDLTSLRLSYTRAELRREDLNPDPLRQFQGWFEEAQQADLTEPYALQLATADAQGRPSVRTVLLRGADERGLTFYTNYESHKGHDLAANPQAEVLFYWAELERQVRAFGTVSRVPEAESNDYFHKRPRESQLAAHASTPQSAPVENRAALEAKFAALHEQFPEGTTIPRPAFWGGYRVQVQEWEFWQGRPNRMHDRFRYARDGDGWRLDRLMP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CAV1_LOXAF
Sequence: MSGGKYVDSEGHLYTAPIREQGNIYKPNNRDMAEEMHEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSSIRINMQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: P4KB2_ARATH
Sequence: MQMAQFLSLVRGDSIESPREITSPSNLISESGSNGWLIRFFDSSFFCEWIAVSYLYKHQHSGVRDYLCNRMYTLPLSGIESYLFQICYLMVHKPSPSLDKFVIDICAKSLKIALKVHWFLLAELEDSDDNEGISRIQEKCQIAATLVGEWSPLMRPHNEPSTPGSKVLNKFLSSKQKLFSLTLSPPTQKSLLFSPTSGSNLQDDGSQLSADDNKIFKRLIPSPKVRDALLFRKSADKEDEECEKDGFFKRLLRDSRGEDDEQRSNSEGFFKRLLKDNKSEEEEISNNSEGFFKRLRSSKGDEEELTSSSDGFFKRLLRDNKGDEEELGANSEGFFKKLLRDSKNEDEEPNANTEGFFKKLFHESKNEDDKVSNAVDDEEKDGFLKKLFKEKFDEKRNGNERNETDETVYTDETSGEDNGREGFFKKLFKEKFEDKPNIGKADDGNESEDDESSEFSLFRRLFRRHPEDVKTTLPSENCSNGGFVESSPGTENFFRKLFRDRDRSVEDSELFGSKKYKEKCPGSPKPQNNTPSKKPPLPNNTAAQFRKGSYHESLEFVHALCETSYDLVDIFPIEDRKTALRESIAEINSHLAQAETTGGICFPMGRGVYRVVNIPEDEYVLLNSREKVPYMICVEVLKAETPCGAKTTSTSLKLSKGGIPLANGDAFLHKPPPWAYPLSTAQEVYRNSADRMSLSTVEAIDQAMTHKSEVKLVNACLSVETHSNSNTKSVSSGVTGVLRTGLESDLEWVRLVLTADPGLRMESITDPKTPRRKEHRRVSSIVAYEEVRAAAAKGEAPPGLPLKGAGQDSSDAQPMANGGMLKAGDALSGEFWEGKRLRIRKDSIYGNLPGWDLRSIIVKSGDDCRQEHLAVQLISHFFDIFQEAGLPLWLRPYEVLVTSSYTALIETIPDTASIHSIKSRYPNITSLRDFFDAKFKENSPSFKLAQRNFVESMAGYSLVCYLLQIKDRHNGNLLMDEEGHIIHIDFGFMLSNSPGGVNFESAPFKLTRELLEVMDSDAEGLPSEFFDYFKVLCIQGFLTCRKHAERIILLVEMLQDSGFPCFKGGPRTIQNLRKRFHLSLTEEQCVSLVLSLISSSLDAWRTRQYDYYQRVLNGIR
What is the function of this protein?
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate (By similarity).  Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs.  Together with PI4KB1, required during polarized root hair expansion and pollen tube elongation.  Functions redundantly with PI4KB1 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway.
What are the official names of this protein?
Phosphatidylinositol 4-kinase beta 2, PI4-kinase beta 2, PtdIns-4-kinase beta 2, Phosphatidylinositol 4-OH kinase beta2, AtPI4Kbeta2, PI-4Kbeta2.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Cell membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to tip-localized membranes in growing root hairs.
Protein: ALG1_SCHPO
Sequence: MLVLKIVLFLSLVIWFNLKKRTDKKRIIVLVLGDIARSPRMQYHAVSFAKLGWKVDLLGYQHPGSSVGLFESHENIRFYPIPSLPAYLQPKNRLQFLFLGPLKVLHQFLALNWALFVRKPASFLFIQNPPCIPVFFIAQCLHILRGTKFIIDWHNFGYSILALKLGKQHTFVKLLKIYEKYMARGAYAHLTVSKRMKDVLQTWGMNPCYVCYDRPPNHFTPIKNEQKKQMSIKKIPCEYNPSSTKLLITSTSWTPDEDIYILWEALNEYDKTLDTPKLLVLITGKGPMKEEFSQYIKKHPLHKVRFCMPWLSIEDYPQVMACADLGVCLHTSSSGLDLPMKVVDLFGCGVPVIALSYPTISELVHDGENGLIVNDSKALSKKMQYLLTHANELNSLKLGALKESEYRWDDEWNKVIPPIVQGSN
What is the function of this protein?
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation.  Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity).
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RL24_LACP7
Sequence: MATTKIKKGDSVKVIAGKDKGKEGKVISVSNGKVLVEGVNTITKHSKASQANPKGGIIHQEAPIDASNVMYVQKGKTTRIGFTTVDGKNGQKKVRVAKATGDIID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ADDA_STAAN
Sequence: MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTDHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKNDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: VF859_ASFWA
Sequence: MCAGFYVAVHPWLEAQSLHKVGHTGNLAARLHDGSYTTCFTDEWKYCFTLETSTKKDAQKIEAGVLYCAQFFRVKNKELVCLLPEKIKQLAEDVANCLDISYTLCDSPAYEMNDSTIVVEPSLPSDPLISKEKLRHLVITPVEDEEHFADDVLFFSTDETRTAIEDRLYQKEAANMGYQELRRSGRAILQMACRCGKTRVAYLILSNYLQGKVLYLVPGLSLLRQTLEKLYQYGISLKNVLLVGSDQTRIVLNHDNIEMTTNPVFIAKRIREAPSLLVIATYQSSTLLVDDFDLIISDECHRICGEWETRPFTHVLLNFKKGHRLFLTATPRYDTPLSMKNRELFGGVAFRYYLREGIEAGYVNDFELQMVAAPKLAHQPSTKEETTKQIIVKQIIMALAHLKTNITAPKMLVFTRDIKQAKELYAELVDQGVYALIAHSTLPRQVILKTFTEFCSSKEPVILLNCRLFQEGVEVPELNAVFFAAPRHSPRDIIQSICRPLNKQVQKPHATIFLPLEVNTENVCLDRFSSIIPFADALASEDPRFYEHLLNPSEVAYPINWIGAHGSVSELLQLARHAIRYGTQGKIDRLTRSERLPWKAAFAELKRTVEICCRYPKINDGFHFGGATLRFDTWYKWVIKSYLQYKNKEPSSLEPYQVSDLESLQDWTTRGVGGPYPWEESMAFLETWLAQNKGELVAIDIHQGGWIGLDATPMERLSGVLTTVSQRDGRSYGKNKKLRPKKGFMIPPQQAQDLDRIFGKHNLKWRKDRVNGFLKEDEHGNYTGEPTCIQEAYRTFKEYVKTNPDYIEKYWPGYAKGKHKHQELPHIWEKGLAPPRYKAFKDGNKQLIQRSPKKKDVKN
What are the official names of this protein?
Probable helicase A859L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus helicase A859L family.
Protein: PUR5_SALHS
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPLADHLLEPTRIYVKSVLELIENVDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQWPAIFTWLQTAGNVSRHEMYRTFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_STRR6
Sequence: MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVVPANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEYDFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRILLPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: GLGB_AQUAE
Sequence: MKKFSLISDYDVYLFKEGTHTRLYDKLGSHVIELNGKRYTFFAVWAPHADYVSLIGDFNEWDKGSTPMVKREDGSGIWEVLLEGDLTGSKYKYFIKNGNYEVDKSDPFAFFCEQPPGNASVVWKLNYRWNDSEYMKKRKRVNSHDSPISIYEVHVGSWRRVPEEGNRFLSYRELAEYLPYYVKEMGFTHVEFLPVMEHPFYGSWGYQITGYFAPTSRYGTPQDFMYLIDKLHQEGIGVILDWVPSHFPTDAHGLAYFDGTHLYEYEDWRKRWHPDWNSFVFDYGKPEVRSFLLSSAHFWLDKYHADGLRVDAVASMLYLDYSRKEWVPNIYGGKENLEAIEFLRKFNESVYRNFPDVQTIAEESTAWPMVSRPTYVGGLGFGMKWNMGWMNDTLFYFSKDPIYRKYHHEVLTFSIWYAFSENFVLPLSHDEVVHGKGSLIGKMPGDYWQKFANLRALFGYMWAHPGKKLLFMGGEFGQFKEWDHETSLDWHLLEYPSHRGIQRLVKDLNEVYRREKALHETDFSPEGFEWVDFHDWEKSVISFLRKDKSGKEIILVVCNFTPVPRYDYRVGVPKGGYWREIMNTDAKEYWGSGMGNLGGKEADKIPWHGRKFSLSLTLPPLSVIYLKHEG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MED17_KLULA
Sequence: MDGFSEYDPEKGIPLAIDPNLISIPVSTSLTTNGNGDEGVNNEDATVFAADDADNAKSQKSLIQNPYEYFGQMPLEQFIPLMLQQRGTGTKFADIHEETLLEEISRENSSKSNNAIQEEDNDDSAIQNVDEKTTTVVNEGVSDSHEMKDEDGDVNMDVPSVESSPKLAEEREPTADANDAQRAISGNQEESITLEEFKMIKKNVLEHVNMALNESSLSLEFVSLLLSSTRTSAGISSMSPYLKKIAPPASLNADKVPLDILDEHEKLTYDIIHKGWNLRSLEDCKRLLKQHYQILSKSVESEYHYWKQISDNITNKDVLFKMKDKNTGRRTLGIKYGFDDSGSCYSADKGIALLRATSEGSQLELVPIIDSGINVGISRGSSEQFVRVRIFTKIEQEDDYLLSGQSSLNELLLSSRSDIKSQIAKLRFFIFEKELMHQLKKEAGQLLPYGVSVENENKVLLELSNEKIEFELINLDEEVTSNYQQEAAKVNDKRANLILVMLNMLLVVMYKKQLWKRLNPNPHSSKSSKGYGKDLVLLRAILGKIRHKKYTQLIEKIVNNAILEKKEDSIMTTNTDITSNDNEPSKNKELATLQREIALFDKILSMPRTDFTINIPEKGKLELSLRSTNHCNAIIHMKYIDVGQVVKFDTRFSEFTEFEEFLNFVYNEFLI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 17, Mediator complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 17 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GGYF2_HUMAN
Sequence: MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGRSSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
What is the function of this protein?
Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:22751931, PubMed:31439631).  In the 4EHP-GYF2 complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (PubMed:31439631).  Also recruits and bridges the association of the 4EHP complex with the decapping effector protein DDX6, which is required for the ZFP36/TTP-mediated down-regulation of AU-rich mRNA (PubMed:31439631).  May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153).
What are the official names of this protein?
GRB10-interacting GYF protein 2, PERQ amino acid-rich with GYF domain-containing protein 2, Trinucleotide repeat-containing gene 15 protein.
What is the protein family that this protein belongs to?
Belongs to the GIGYF family.
Protein: PG141_VACCC
Sequence: MISNYEPLLLLVITCCVLLFNFTISSKTKIDIIFAVQTIVFIWFIFHFVHSAI
What is the function of this protein?
Protein probably involved in counteracting host defense, since it enhances virulence in vivo.
What are the official names of this protein?
Virion membrane protein OPG141.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG141 protein family.
Protein: TRMD_VIBA3
Sequence: MWVGIISLFPEMFRSVTDFGVTGQAVKKGLLSIETWNPRDFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIQTAKQAAPGKTKVIYLSPQGRKLDQQGVEELATNENLLLICGRYEGVDERIIQSEVDEEWSIGDFVMTGGELPAMTLIDSVSRFVPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDDKDVPSVLKSGNHKDIRRWRLKQSLGRTWLRRPELLENLALTDEQEQLLAEFIKEQRS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTP2_YEAST
Sequence: MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQNQIKPCKDLDDVNIRRNNSNRHSKILLLDLCAGPNTNSFLGNTNAKDITVLSLPLPSTLVKRSNYPFENLLKNYLGSDEKYIEFTKIIKDYDIFIFSDSFSRISSCLKTTFCLIEKFKKFICHFFPSPYLKFFLLEGSLNDSKAPSLGKNKKNCILPKLDLNLNVNLTSRSTLNLRINIPPPNDSNKIFLQSLKKDLIHYSPNSLQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKKLFNNFETLENFEMQRLEKCLKFKKKPLHQKQLSQKQRGPQSTDDSKLYSLTSLQRQYKSSLKSNIQKNQKLKLIIPKNNTSSSPSPLSSDDTIMSPINDYELTEGIQSFTKNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYWNNLSYSNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDSCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFALQKQIKNALPC
What is the function of this protein?
Major phosphatase responsible with PTP3 for tyrosine dephosphorylation of MAP kinase HOG1 to inactivate its activity.  May also be involved in the regulation of MAP kinase FUS3.  May be implicated in the ubiquitin-mediated protein degradation.
What are the official names of this protein?
Tyrosine-protein phosphatase 2, Protein-tyrosine phosphatase 2, PTPase 2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS10_STAA1
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRAVHMYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GLGA1_SYNY3
Sequence: MKILFVAAEVSPLAKVGGMGDVVGSLPKVLHQLGHDVRVFMPYYGFIGDKIDVPKEPVWKGEAMFQQFAVYQSYLPDTKIPLYLFGHPAFDSRRIYGGDDEAWRFTFFSNGAAEFAWNHWKPEIIHCHDWHTGMIPVWMHQSPDIATVFTIHNLAYQGPWRGLLETMTWCPWYMQGDNVMAAAIQFANRVTTVSPTYAQQIQTPAYGEKLEGLLSYLSGNLVGILNGIDTEIYNPAEDRFISNVFDADSLDKRVKNKIAIQEETGLEINRNAMVVGIVARLVEQKGIDLVIQILDRFMSYTDSQLIILGTGDRHYETQLWQMASRFPGRMAVQLLHNDALSRRVYAGADVFLMPSRFEPCGLSQLMAMRYGCIPIVRRTGGLVDTVSFYDPINEAGTGYCFDRYEPLDCFTAMVRAWEGFRFKADWQKLQQRAMRADFSWYRSAGEYIKVYKGVVGKPEELSPMEEEKIAELTASYR
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 1, Starch [bacterial glycogen] synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.