PharMolix/UniProtQA huggingface dataset:
Protein: PSBI_SACOF
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y2845_ACIAC
Sequence: MVELKTFLLYAVTALAEIAGCYLPWLWLRQDRSAWLLVPGAACLALFAWLLTLHPAAAGRVYAAYGGVYVAVALGWLWAVDGIRPDRWDLAGAAVTLAGMAIIAFAPRGAA
What are the official names of this protein?
UPF0060 membrane protein Aave_2845.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACSA_BRASO
Sequence: MSEKIYDVPAEWAKRAFVDDAKYQEMYASSIRDPNGFWAEQAKRVDWIHAPTKIENVSYAPGNISIKWFEDGVLNAAYNCIDRHLATRADQTAIIWEGDDPADSKHITYRQLHDEVCKMANILRNRNVKKGDRVTIYLPMIPEAAYAMLACARIGAIHSVVFAGFSPDSLAQRIKDCDSKVVITADEGLRGGRKVPLKANVDAALNKVDNVDWVVVVKRTGGKIEMNPTRDLWYHEAAEMVTTECPVEHMNAEDALFILYTSGSTGQPKGVLHTTGGYLVYASMTHQYVFDYHEGDVYWCTADVGWVTGHSYILYGPLANGAVTLMFEGVPNYPDNSRFWNVIDKHKVNIFYTAPTAIRALMQGGDGPVTKTSRESLRLLGSVGEPINPEAWEWYHRVVGDNRCPIVDTWWQTETGGILITPLPGATRLKPGSATRPFFGVVPEIVDADGNTLEGATEGNLCLTRSWPGQMRTVYGDHARFEMTYFSTYKGKYFTGDGCRRDADGYYWITGRVDDVINVSGHRMGTAEVESALVAHPKVSEAAVVGYPHDIKGQGIYAYVTLMAGETPSEELRKELVGWVRKEIGPIASPDQIQFSQGLPKTRSGKIMRRILRKIAEDEPGALGDTSTLADPAVVDDLVQHRQNRKEKQA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PROA_BRUO2
Sequence: MLVKADMTKDIAQVMAEVGRKAKAAAAPLSIATSEQKNKALNAAADAILEARADILEANRLDLANAEKNGMAASFVDRLTLNEARIDAIAEGIRTIATLPDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSAHSSAAIHKALVKGLEAANLPADAIQIVPVTDRAAVGEMLKGLGGAIDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGICGAAETLLVDRAVASTHLAPILGDLAAGGCEIRGSAEVLALYPAAKPATEEDWSTEYLDAIISVALVDGISGAIDHINRYSSHHTEAIVAEDAQTVARFFNEIDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_CLOB6
Sequence: MNTKEIVNKYEFKFNKNLGQNFLIDESVLEDIIEGAEINKEDTVIEIGPGVGTLTKELLERAKEVYSIELDGDLIPILQEELKEYNNFTLIHKDALKIDFNRLMENKDSIKLVANLPYYVTTPIISRLLTEKCDFKSLTIMIQKEVAERINAEPNCKEYGSLTVLVQYYCDTKIIRKVSPNCFIPRPKVDSIVIKLDRLSEPRVRVKSEKLFFNVVRSSFNMRRKTLWNSLKSLNINKESMENAFERAGIDSKRRGETLSIEEFGKLSDCIYDIL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPR_TERCL
Sequence: GTQTNAPWGLARLIS
What is the function of this protein?
Protease capable of hydrolyzing gelatin and cell surface heparan sulfate proteoglycans (HSPGs) in vitro.
What are the official names of this protein?
Alkaline serine protease, AkP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UHRF2_HUMAN
Sequence: MWIQVRTIDGSKTCTIEDVSRKATIEELRERVWALFDVRPECQRLFYRGKQLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAKPCSNSPPKVKKAPRVGPSNQPSTSARARLIDPGFGIYKVNELVDARDVGLGAWFEAHIHSVTRASDGQSRGKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPESGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPGAHPLSFADGKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSKKKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYPSDKEGKKPKGQSKKQPSGTTKRPISDDDCPSASKVYKASDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPNFLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPACRHDLGQNYIMIPNEILQTLLDLFFPGYSKGR
What is the function of this protein?
E3 ubiquitin ligase that plays important roles in DNA methylation, histone modifications, cell cycle and DNA repair (PubMed:15178429, PubMed:29506131, PubMed:27743347, PubMed:23404503).  Acts as a specific reader for 5-hydroxymethylcytosine (5hmC) and thereby recruits various substrates to these sites to ubiquitinate them (PubMed:27129234, PubMed:24813944).  This activity also allows the maintenance of 5mC levels at specific genomic loci and regulates neuron-related gene expression (By similarity).  Participates in cell cycle regulation by ubiquitinating cyclins CCND1 and CCNE1 and thereby inducing G1 arrest (PubMed:15178429, PubMed:15361834, PubMed:21952639).  Ubiquitinates also PCNP leading to its degradation by the proteasome (PubMed:14741369, PubMed:12176013).  Plays an active role in DNA damage repair by ubiquitinating p21/CDKN1A leading to its proteosomal degradation (PubMed:29923055).  Promotes also DNA repair by acting as an interstrand cross-links (ICLs) sensor.  Mechanistically, cooperates with UHRF1 to ensure recruitment of FANCD2 to ICLs, leading to FANCD2 monoubiquitination and subsequent activation (PubMed:30335751).  Contributes to UV-induced DNA damage response by physically interacting with ATR in response to irradiation, thereby promoting ATR activation (PubMed:33848395).
What are the official names of this protein?
E3 ubiquitin-protein ligase UHRF2, Np95/ICBP90-like RING finger protein, Np95-like RING finger protein, Nuclear protein 97, Nuclear zinc finger protein Np97, RING finger protein 107, RING-type E3 ubiquitin transferase UHRF2, Ubiquitin-like PHD and RING finger domain-containing protein 2, Ubiquitin-like-containing PHD and RING finger domains protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Enriched at genomic loci that are enriched for 5-hydroxymethylcytosine (5hmC).
Protein: ILVB_CORGL
Sequence: MNVAASQQPTPATVASRGRSAAPERMTGAKAIVRSLEELNADIVFGIPGGAVLPVYDPLYSSTKVRHVLVRHEQGAGHAATGYAQVTGRVGVCIATSGPGATNLVTPIADANLDSVPMVAITGQVGSGLLGTDAFQEADIRGITMPVTKHNFMVTNPNDIPQALAEAFHLAITGRPGPVLVDIPKDVQNAELDFVWPPKIDLPGYRPVSTPHARQIEQAVKLIGEAKKPVLYVGGGVIKADAHEELRAFAEYTGIPVVTTLMALGTFPESHELHMGMPGMHGTVSAVGALQRSDLLIAIGSRFDDRVTGDVDTFAPDAKIIHADIDPAEIGKIKQVEVPIVGDAREVLARLLETTKASKAETEDISEWVDYLKGLKARFPRGYDEQPGDLLAPQFVIETLSKEVGPDAIYCAGVGQHQMWAAQFVDFEKPRTWLNSGGLGTMGYAVPAALGAKAGAPDKEVWAIDGDGCFQMTNQELTTAAVEGFPIKIALINNGNLGMVRQWQTLFYEGRYSNTKLRNQGEYMPDFVTLSEGLGCVAIRVTKAEEVLPAIQKAREINDRPVVIDFIVGEDAQVWPMVSAGSSNSDIQYALGLRPFFDGDESAAEDPADIHEAVSDIDAAVESTEA
What are the official names of this protein?
Acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: SPEH_GEOSW
Sequence: MDTMGRHVISELWGCDFDKLNDIEFIEKTFVDAALKSGAEIREVAFHKFAPQGVSGVVIISESHLTIHTFPEHGYASIDVYTCGHLDPTIAADYIADKLGAQTRETIELPRGMRPIEVKKAQAL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: PROA_MYCLE
Sequence: MRQEVHDAARRARVAARALAVMPTVAKDHALRAAATAVTAHTEEILAANAEDLQAARATDTLAATLDRLALDRQRIDQIAGGLRQVAALPDPIGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNITVDAFGLAFKSGNAALLRGSSSAAKSNQALVEVLHAALVSEDLPADAVQLLSAADRSTVTHLIQARGLVDVVIPRGGANLIDAVVRDAQVPIIETGVGNCHVYVHQAADLEVAERILLNSKTRRPSVCNAAETLLIDAAIADHTMPRLVAALQGAGVTVHGGLSGDPDKADLCREYLSMDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNMAAAQRFADGVDSATVMVNASTAFTDGGQFGFGAEIGISTQKLHARGPMGLSEMTSTKWIVWGDGQIRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_HAEIN
Sequence: MPFKEITPQQAWEMMQQGAILVDIRDNMRFAYSHPKGAFHLTNQSFLQFEELADFDSPIIVSCYHGVSSRNVATFLVEQGYKNVFSMIGGFDGWCRAELPIDTTY
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_SYNV
Sequence: MSTTPTITLADLERIREPYKVLSKTARPENPSGQCTYREYLFSDAVKYPIYKRATMTNEEIVTFFGKITSDKHTHMTESDMWTFVQCALSLKDPVDRSSIFDKGFWDANHLCADYATAQPANTGKVAMSHHNPGVVVTQLVPKYDTGGSSSQETESMASKAEAISFYFAWLTRFSVKQAPNTINVLYDRVRATYLKFYSTSSSIFDTFRPSNTWLQGLKDAFDTFPRVKNTLILHVAHAETYFRPTPKIFNVLRFLFFQNLEFMGLHAYVSIVTIMSKVALPPSQVLSWLRVSGSEMAIDEAFMIMNTLDNGMIDNGHNAERLWKYARCLDQGYFNRLQSSYSAELIAMLAYIEINMGISTEVGYNSPLNIYAIANNKAVKEVGRMKADVFIQCKNSVVSLTQDASVIDKVYAAAQQKHIRSEEAARPSEQNKEDEVVAMDTDAPSRKRRSDALTTEKPKKALPAIIKLPNIPDF
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CCD30_MOUSE
Sequence: MCQEGLFRLALSSPRKQTACSLGERRTLAEALGLVDSTLESRRDPNSSLQKEFPQHQDEDQSRAAAPQDCLLRDVECIAQKLEASLEEIHRGAREPREEREQRTLGDALENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKVLGEMYLTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREEETVITDNAAFEILKKILPLQNSSFSGTGFVLSAENLQETELHKWEGAAAIPKSPEPLSRSQDSESGYINVTSLKETHNTQGDQKPEL
What are the official names of this protein?
Coiled-coil domain-containing protein 30, Prefoldin subunit 6-like protein.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: NODI_RHIEC
Sequence: MPVNGARRSDERMFMTAIDFSDVSKTYGDKAVVSALSFRVSPGECFGLLGPNGAGKSTIARMILGMTAPDAGKITVLGVPVPAQARLARKGIGVVPQFDNLEPEFTVRENLLVYSRYFGMNTRKVEAVMSSLLEFARLESKVNARVSELSGGMKRRLTLARALINDPQLLVMDEPTTGLDPHARHLIWERLRSLLTRGKTIILTTHFMEEAERLCDRLCVLEGGRSIAEGRPHDLIDELIGCEVIEIYGGDPHELESLVGPYADRIEISGETLFCYVSDPEQVRVRLRQRAGLRILQRPPNLEDVFLRLTGREMEK
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit is responsible for energy coupling to the transport system.
What are the official names of this protein?
Nod factor export ATP-binding protein I, Nodulation ATP-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3.A.1.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EUTC_AZOVD
Sequence: MSDRSPATENPWQQLRRLTPARIALGRAGASLPTAAHLAFQFAHAQARDAVHLPFEPAALQDGLRRRGLDGLLLRSAARDRDTYLQRPDLGRRLRPECATRLRDWHAEHGGGRDLAIVVADGLSALAVQRHALPLLDCLLERLPAEGWSLAPISLVEQGRVAVADEIGELLGARMTVILIGERPGLSSPDSLGLYFTFAPRVGLTDAARNCISNVRPEGLSYAMAAHKLLYLMREACRRRLSGVELKDEAEVARLDGAGSGPGNFLLGEG
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: SYP_ROSDO
Sequence: MRLTRYFMPVLRENPAEAQIVSHRLMLRAGMIKQNAAGIYSWLPLGFKVLRKLENIVHEEQIRAGHVPMLMPTMQSADLWRESGRYDAYGPEMLRIRDRQDRDMLFGPTNEEMITDIFRSHVSSYKDLPLTLYHIQWKFRDEMRPRFGVMRGREFFMKDGYNFDLTKEDALHAYNRHLVSYLRTYERMGLQAIPMRADSGPIGGDDTHEFLVLADTGESEVFYDSAVTDLTFGDRDIDYDSVEQCQGVMEEFTNLYARTDETHDQALFAAIPAERQRQARGIEVGQIFYFGTKYSDAMGAKVQGPDGKPTAVHMGSHGIGVSRLVGAIIEASHDEKGIIWPEGVTPFHCGIVNLKQGDTEADAACDALYASLRALGLDPLYDDRKERAGGKFATMDLIGLPWRITVGPRGLKNGVVELTSRKTGESSELPPEEAIEKIAKIYAPHHVSGNL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_THIDA
Sequence: MGRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRISGYMLEAALEAGFTAAGVNVLMTGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFFSASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDAAARYIEFCKSTFPNRLDLRGMRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHADIGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHALARIHVPFERAKVGDRYVLKRLHANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRETGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAVADAESALNGSGRIVLRASGTEPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y3962_ANADE
Sequence: MPKDAPAGLAPGFLVAAPALADPNFNGSLVLMAEHHAQGALGFVVNRPGPITVADVLGGLDERLRERAEGAGRADDPVLVGGPVQPERLWILFRPGPTAPEEGAVALGSGLALGGSRELLEALVRSRDPGPYLLLLGYAGWAPLQIEHEVGEGAWVPLPLQGDLVFDVPMEKRWETAVRRLGLDPAGFLVGGGGAEA
What are the official names of this protein?
UPF0301 protein Adeh_3962.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: IMA1_CAEEL
Sequence: MGDEFRPSHEERSKMYKSNVRDQNEMRRKRREDEVQIRKNRRDEKFERNRQITVQRSLSHEETSELLKSVADGLQSMQETTIHEALTVLHENLNNTVWTIHVLVKVQILHKLSDVYCNRVISQTTRLLISRTLLKISGIDEVKYERYSSDDRCIQSLVFNISTYGSSEDILCDTFQSIACFIIRSITYRNLALDCAIVSELIDASTINMSIILHRSLMWLVFLFCEKLDRCSPHVDEIAPLLEIISNGIQSTDAMVQTDAASSCASLAEWPPIYHYMSDLKLCSKLVANLRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVNVSYMSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLLQFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSVDIHARAYTIIDRFYVDDDAPLNDDPFAGYQRNNIDDTIEKMIREPIMDQPFSF
What is the function of this protein?
Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Promotes docking of import substrates to the nuclear envelope.  Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity).
What are the official names of this protein?
Importin subunit alpha-1, Karyopherin subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BUCAT
Sequence: MTSTKDKIEKLRKILLKYEYFYHTLNQSIISDAEYDYLFRQLYELELKNKELIPSDSPTQKVGSHILQKFKKIKHFSPMLSLENTFDVNGYLNFKKRIKKSIHNNEPLSFCCELKLDGVAISIIYEEGIFVRAATRGDGFEGENITSNARMIDSIPLKLKGIDIPKRLEIRGEVFMLKSNFIKLNKKYKLNQNKYFSNPRNAAAGSLRHIDPNITAERKLIFSCHGCDFFVKTNKELTTHYQRLMKCLSWGIPVNKEIVICSSDIEIIQFYKKIAQKRNFLDFDIDGIVIKVNSLELQKKIGSTTKSPRWAIAFKFSPKERITTLNDVKFQVGRTGVITPVAYFNPVYISGVMISKASLHNKNEIERLNLHFNDTITICRSGDVIPRLLNVIEIRRCDNAKKIIFPSFCPVCNTELLENIEEKLIRCHSGLTCDAQKKQALYHFFSKKSLYVVGLGPKIINELVEKGLVKNPIDFFYLKDIDLIQLKNVGKRKSIKIINSIKKCKKTTLKCFIYALGIPGVGEVVAGKIANYFIKLDKLMNSNILELNCISGVGKIISNNIFNYFSTISNREMVVKLIKQAGIFLNDQEIHKINSEKTYFFNKKIVLTGVFKSFSRIELKTILLSLGAKISNNISRKTDFLIYGNNFGSKFFRAKDLDVKIINQEELNSLIRIKEQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CH601_CORDI
Sequence: MAKLIAFNQEAREGILKGVDALANAVKVTLGPRGRNVVLQKAFGSPTVTNDGVTIAREIDLSDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQAVVTEGLRNVAAGANPIELNRGIAAGSEFVVGKLRERATDVSSAADIANVATVSSRDPEVGDMVAAAMEKVGKDGVVTVEESQSIESYLDVTEGVSFDKGFLSPYFITDTDTQHAVLEQPAILLVRNKISSLPDFLPVLEKALEASKPILIIAEDVEGEPLQTLVVNSIRKTLRAVAVKAPYFGERRKAFMDDLAVVTGATVIDPEVGVNLNEAGAEVFGTARRVTVTKDETIIVDGAGTAEAVENRRAQIRREIENTDSAWDREKAEERLAKLSGGVAVIKVGAATETEVSERKLRVEDAINAARAAAQEGVIAGGGSALVQISKELREFAQEFEGDAKIGVIALANALAKPTYWIADNAGLDGAVVVSKVSELPNGEGFNAATLEYGNLIEQGIIDPVKVTHSAVVNATSVARMVLTTEASVVEKPAAPAPEAGHHHHHHH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_SODGM
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTDAPLLRFEVGSKPPQMAVLQPASQHASEAPSQAAVARPRPSRPSWDNAPVQPELSYRSNVNPKHNFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENAIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_SALPC
Sequence: MNNRVHQGHLARKRFGQNFLNDRFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELSAQLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDIRVLSRITTEAFNQRRKTIRNSLGNLFSVETLTEMGIDPAMRAENISVAQYCQMANYLSENAPLKES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWT1_SCHPO
Sequence: MDRMEIDDQAGIDFVTESINSERARNRWSTSHIPSLSEINPSSFQSPSPSPFASSTSLASKPARYSKPLGLFVLDTNFLLSHLSLCQNLIEFLTARCPRLVVVLPWTVLQELDGLKSESSSTCGYLARQAHNFLLQCFRSNVSSLRGQKVHEHCSSTEKGDDAILDCCIYYQEEKLIPAVLLSDDKNLSIKAAVHHIQSLSFSKGLEAASIVQTSFPSAFSSNSENLENLSMDIDLTVSQPLATATNHRNQGASTVDIPMDRTHDNSIWASRYAHFPPYDKKKDTTRSAADYIPYTYTALTKEEILHASHPRACKLLDQITKIMVEETAFLLSRHLLKLWGDYDLAMTKLLASPQFPPQNINDVGHELYIHWYTCFDGYLPAQERSNLKSKAELWNEWMLWAERGIGIGPKNQEELQTYVTFWSNIWTLLSRREILGDQASTYIGFREQNIEKWVERSGRERILS
What is the function of this protein?
Involved in transcription.
What are the official names of this protein?
Transcriptional protein swt1.
What is the protein family that this protein belongs to?
Belongs to the SWT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.