PharMolix/UniProtQA huggingface dataset:
Protein: RL5_BACC0
Sequence: MNRLKEKFQKEITPALVSKFNYKSVMQVPKIEKIVINTGVGDAVSNSKALDNAVEELTQITGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSKKSFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTAKTDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYE_BACCZ
Sequence: MEKQVRVRYAPSPTGHLHIGNARTALFNYLFARHQDGKFIIRIEDTDVKRNVAGGEESQLKYLKWLGMDWDEGVDVGGEFGPYRQTERLDIYKKLYEDLLERGLAYKCYMTEEELEAEREGQIARGETPRYAGNHRDLTEAQVKEFEAEGRIPSIRFRVPADRDYTFKDIVKDEVAFHSNDFGDFVIVKKDGIPTYNFAVAVDDHLMEITHVLRGDDHISNTPKQMMIYEAFGWDIPQFGHMTLIVNESRKKLSKRDESIIQFIEQYKELGYLPEAIFNFIALLGWSPVGEEEIFSQEEFIKMFDAARLSKSPALFDSQKLKWMNNQYMKKQDLDTVVELSLPHLVKAGRIGETLSEQEQAWIRDVIALYHEQMSFGAEIVELSEMFFKDHVDYEEEGQEVLKGEQVPEVLRAFAGQVEALEAMEPAAIKAAIKAVQKETGHKGKNLFMPIRVATTGQTHGPELPNAIALLGKEKVLNRLQKVIG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCX_PORPU
Sequence: MSDYILEIKDLHASVNDVPILKGVNLSIKPGEIHAIMGPNGSGKSTLSKVIAGHPAYSLLNGDILFYGRSILKMEPDERARAGIFLAFQYPVEIPGVSNADFLRIALNARRKFRELPELSPLEFFQLITEKINLVGMKESFLSRNVNEGFSGGEKKRNEILQMALLESNLSILDETDSGLDIDALKIIAQGINTLATSTNSIVLITHYQRLLDYIIPNFVHIMSDGKIVKTGNVNLAQDLEKHGYDWIKST
What are the official names of this protein?
Probable ATP-dependent transporter ycf16.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ycf16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VP1_POVS1
Sequence: MPPAKRKGECPGAAPKKPKDPVRVPKLLIRGGVEVLEVKTGVDSITEVECFLTPEMGDANEHLRGYSQRVTCDVTFENDAPQKKTLPCYSTARIPLPNLNEDLTCGNILMWEAVTVKTEVLGVTSMLNLHAEAQKVHDNGAGRPVQGSNFHFFSVGGEPLELQGVLHNYRTTYPEGTIAPKNPTAESQVMNTEHKAYLDKTGAYPVECWVPDPSRNENTRYFGTYTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAVDICGLFTNSSGTQQWRGLSRYFKISLRKRSVKNPYPISFLLSDLINRRTTRVQGQPMYGMNAQVEEVRVYDGTEELPGDPDMMRYIDKYGQHQTKML
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with sialic acids on the cell surface to provide virion attachment to target cell.  Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GMM_SALTI
Sequence: MFLRQEDFAAVVRTTPLISLDFIVENGQGEILLGQRLNRPAQGYWFVPGGRVCKDETLEAAFARLTQAELGVRLPLAAGTFYGVWQHFYDDNFSSEDFSTHYIVLGFRLRVAESDLRLPDAQHGSYRWLTPEQLLAGDNVHENSRAYFSPDAPAVGL
What is the function of this protein?
Hydrolyzes GDP-mannose.
What are the official names of this protein?
GDP-mannose mannosyl hydrolase, GDPMH.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: CUEB_CONVR
Sequence: QQMCGRCGGTGQIIKNECKTCHGKKVTK
What is the function of this protein?
In vitro, inhibits proliferation of the mice ovarian cancer cells ID8.
What are the official names of this protein?
Conotoxin Vi14b.
Protein: Y492_PASMU
Sequence: MYVYDIPNCNEFISMYGCDCEIEEFIQTCFFHNKDKTMKLNLSFDRTINSLRIIIYHGNKICFDLYKENLKSILLDENGNFISFFLECMQIELSIYPEFSVFIR
What are the official names of this protein?
Uncharacterized protein PM0492.
Protein: RPOC_BURM7
Sequence: MKALLDLFKQVQQEEIFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRSINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAINGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVRNEDTSEGAPQFVPKISLYATTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPTQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVIDRGGNETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAASDVVNPETQETLYEAGALLDETAVEDIERLGIDEVRVRTALTCETRYGLCASCYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGTVRFTASMRYVTNAKGEQIVISRSGEALITDDIGRERERHKIPYGATLLQLDGAAIKAGTQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQAAKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTVSFGKDTKGKQRLVITDLEGNQHEFLIAKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPATYDNILLGITKASLSTDSFISAASFQETIRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKEQSDRERFDQIAAEEAFEFGTPSAPAEEPQHPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CSM2_STRTR
Sequence: MAILTDENYVDKAERAISLLEKDNKGNYLLTTSQIRKLLSLCSSLYDRSKERKFDELINDVSYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYGGKD
What is the function of this protein?
This subunit may be involved in monitoring complementarity of crRNA and target RNA.
What are the official names of this protein?
CRISPR system Cms protein Csm2, CRISPR type III A-associated protein Csm2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm2 family.
Protein: PALI_NEUCR
Sequence: MLRPATPLAVLLFAAFGLLTLATISTPIIKQIPLSSFEIKDVGDLSFGVFGYCTSSGCSPIEIGYDTSAFSDKINSDFDIPRATRSTLSSILIVHPVAALITLINFVLAIVAHFHSPSHSARYLLILFIVSFVDFIVCLLCFLVDVLLFIPHLSWGSYIVVAATILVAFCGLVTCAMRRTLVNRKANRKRIAENAEMSGENYYNRQAQTAPVTQVTGPQPTVPMISGANGGGDKLPEFTTFEKKDDRSEERIPLTSVSPIERSPATLVNDSTPPNFMDGAPSRSPSTTPVGRDQYGNPLPPQDGYAMRVGPQNERLNSRGRGGMPPGGYRGRGGFPGPGRGGGPPQNGRGGYGPPGRGRGGYGPPPRGYGGPGPRGGRGPPPQGYQGGPDRRPSPGAPYGPGPGVGTYGPSQPSPYANRQQSPGPQFAAPGYGNPEQPGPQYSAYNPRRVSLPRAESPPPLPGIDDGMPGPAVELDASPANRGVGQYGIRDSDSDVAGMLAMQQARVPDPDRGNDANGHSQEGPNDVYVPPRQAWNQGFVGSTPGLAPPTARGPTRPISEAVTATVASDYYEDVDPRFAEPSAAADKRPPPISMQSPPASNSYDDIPNRARSPAESENSNFTSISQRGINPRWNSANAPMPPPVAGVYAGGGGGGNVVPRRPVNRPGAGPADGSDLFLNSNPDFQLPGRGGNMPRAAGPR
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palI/prr-5, pH-response regulator 5.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPAP3_CHICK
Sequence: MTASNKALELQLQMKQNAEELQDFMRELESWEKDIKEVDSELRKQSGVSEENLPPIRNKTFKKKKKSKTKVPSKTTTEENKKNKIKSYDYEAWGKLDVDKILEELDKDDSTHDSVSPESDSEEDGIHIDKEKALAEKEKGNKYFKQGNFDEAIKCYTRGMHSDPFNPVLPTNRASAFYRMKKFSVAESDCNLALALDKNYTKAYARRGAARFALKNFQGAKEDYEKVLELDANNYEAKNELKKIEQALSSESSEQKEFEEAVRSELTENERRCIEEEQLKQKAVTEKDLGNGYFKEGKYEAAIECYTRGIAADGTNALLPANRAMAYLKIQKYEEAENDCTQALLLDASYSKAFARRGAARVALGKLKEAMQDFEAVLKLEPGNKQAINELTKIRNELAEKEQSCHEEYPAVLIKESEIKNIVKLTHNPLNLKSTKPLRRIAVEEVDDDVLNSDFSSSTSLVNNWKNSVNIETTENLDQDDQLTSMDIPKAKQLKIEEITDVSSPQLPAGAKGVSSVLHPSMNKQIERENKASFRSASPVPAIPANSFQLESDFRKLKDCPEKMYLYLKQIEPSIYPKLFQKSLDPDLFNQILRILHDFYIEKEEPSLILEILQRLSELKRFDMAVMFMSGSEKKITQVLFSHMKHMGLKDTSVEQLEKKYAVFS
What is the function of this protein?
May for an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein.
What are the official names of this protein?
RNA polymerase II-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the RPAP3 family.
Protein: GGT24_PUNGR
Sequence: MGSESLVHVFLVSFPGQGHVNPLLRLGKRLASKGLLVTFTTPESIGKQMRKASNIGEEPSPIGDGFIRFEFFEDGWDEDEPRRQDLDQYLPQLEKVGKEVIPRMIKKNEEQNRPVSCLINNPFIPWVSDVAESLGLPSAMLWVQSCACFAAYYHYYHGLVPFPSESAMEIDVQLPCMPLLKHDEVPSFLYPTTPYPFLRRAIMGQYKNLDKPFCVLMDTFQELEHEIIEYMSKICPIKTVGPLFKNPKAPNANVRGDFMKADDCISWLDSKPPASVVYVSFGSVVYLKQDQWDEIAFGLLNSGLNFLWVMKPPHKDSGYQLLTLPEGFLEKAGDKGKVVQWSPQEQVLAHPSVACFVTHCGWNSSMEALSSGMPVVAFPQWGDQVTDAKYLVDVFKVGVRMCRGEAENKLIMRDVVEKCLLEATVGPKAAEVKENALKWKAAAEAAVAEGGSSDRNIQAFVDEVKRRSIAIQSNKSEPKPVVQNAAVADHFGAKATTNGVAADLAGSNADGKVELVA
What is the function of this protein?
Glucosyltransferase that catalyzes the formation of 1-O-beta-D-glucose esters with hydroxybenzoic acids and cinnamic acid including its derivatives as preferred glucosyl acceptors.  Has significant activity with gallic acid (3,4,5-trihydroxybenzoic acid), 3,4-dihydroxybenzoic acid, 4-hydroxybenzoic acid, cinnamic acid, sinapic acid, coumaric acid, caffeic acid and ferulic acid in vitro.  Gallic acid is the predicted native substrate of the enzyme, which thus catalyzes the formation of 1-O-galloyl-beta-D-glucose, the first committed step of hydrolyzable tannins (HTs) biosynthesis, with punicalagin isomers being the major HTs of pomegranate.  Catalyzes the formation of flavonoid glucosides with genistein, apigenin and luteolin in vitro.  Has low activity with benzoic acid, 2-hydroxybenzoic acid, 3-hydroxybenzoic acid, 2,4-dihydroxybenzoic acid, naringenin and quercetin.  No activity with catechol, resveratrol, chlorogenic acid, catechin and epicatechin (building blocks of proanthocyanidins) or cyanidin, delphinidin and pelargonidin (the three anthocyanidins).
What are the official names of this protein?
Gallate 1-beta-glucosyltransferase 84A24, UDP-glucose:gallate glucosyltransferase, UDP-glycosyltransferase 84A24.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_BURCJ
Sequence: MAKTASPGATPPGNGTEPLPDNYEMALAELETLVARMEGGALSLEDSLAAYRRGATLVAFCQQQLEKVEQQVRVLDGATLKPLSSGTAATDGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_HAEIN
Sequence: MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFEMYIVTEPGMTDLERGQLLTEEQYLDAEDRWQDEFEAKMGAEAIQDLLKGMDLEAECEKLREELQETNSETKRKKITKRLKLLEAFVQSGNKPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYAKLESRGYATTIKAAKKMVEREDAIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPANGDPIIVPSQDVVLGLYYMTREKVNGKGEGMLLQDPREAEKAYRTGEAELHSRVKVRITEYVKNEAGEFDAKTTLTDTTIGRAILWMIAPKGMPYSLFNQTLGKKAISKLINEAYRRLGLKEAVMFADQIMYTGFAYAARSGSSVGIDDMEIPAKKYEIISAAEEEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSQEEVINREGNPEKQASFNSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVIVEDDCGTHEGLVMTPLIEGGDEKVPLRELVLGRVAAEDILKPGTEEVLIPRNTLLDEKLCDVLDANSVDSVKVRSVVTCDTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSVQVKNTGTVHLMNAKFVTNDESKLVLTSRNTELTITDAFGRTKEHYKVPYGAVLSKGDGQEVTAGETIANWDPHTMPVVSEVSGFVKFVDIIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPTIKLVDANGNDIFLPETDVLAQYFLPGKAIVSLDDGTAVKVGEPLARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFEGEMVQRGDVISDGAETPHDILRLRGVRAVTEYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKAVITKAYDSEFLEGEQVEVARVKIVNRQREAEGKPPVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRHKHRLVDDVVAKLSEEDEAAIADEFVITADDATQNLATLLNSEIED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: QOR2_ECOLI
Sequence: MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALAAQGITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAYTSLLHADTSPLGLADEHIETEKMLADSGIVYTLLRNGWYSENYLASAPAALEHGVFIGAAGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVTYQNLSEADFAAALKSVGLPDGLADMLADSDVGASKGGLFDDSKTLSKLIGHPTTTLAESVSHLFNVNN
What is the function of this protein?
Quinone oxidoreductase that may play some additional role beyond quinone reduction.  Potential redox sensor protein.  Overexpression induces retardation of growth.
What are the official names of this protein?
Quinone oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: UB2Q1_MOUSE
Sequence: MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).  Involved in female fertility and embryo implantation (PubMed:23108111).  May be involved in hormonal homeostasis in females (PubMed:23108111).  Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (PubMed:18511602).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 Q1, E2 ubiquitin-conjugating enzyme Q1, Galactosyl transferase-associated protein, GTAP, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, filopodium. Cytoplasm, cytosol.
Protein: NS1_I00A1
Sequence: MDSHTVSSFQVDCFLWHVRKQVADQDLGDAPFLDRLRRDQKSLKGRGSTLGLNIETATCVGKQIVERILKEESDEAFKMTMASALASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCVRMDQAIMDKNIILKANFSVIFDRLENLTLLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNETGGPPFTPTQKRKMAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: CYB_POLOR
Sequence: MAIIRKTHPLAKIINSAFIDLPAPSNISSWWNMGSLLGLCLIAQIITGLFLAMHYVSDINSAFSSVAHICRDVNYGWLIRNFHANGASLFFICIYLHIARGLYYGSYLYTETWNMGVILLLLTMMTAFVGYVLPWGQMSFWGATVITNLLSAIPYIGDTLVQWIWGGFSVDKPTLTRFFAFHFILPFAIAAASLVHIVFLHETGSNNPVGINSDADQIPFHPYFTFKDLLGFIILLLIIIMLALLSPNLLNDPGNFTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLVPLLHTSKIRSATFRPLFKITLWILAADVLILTWIGGQPVEDPYIIIGQAASILYFLIFLVLMPLSGWLENKMLNRD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSB5_SCHPO
Sequence: MNSIVSKYTQSTNNDDPKKIIEEEGFTNRFDVVPVPQSSLYLRNLTDETKNKHCLIKMNHGTTTLAFRYQHGIVVCVDSRASAGPLIASQTVKKVIEINPYLLGTLAGGAADCQFWETVLGMECRLHQLRNKELISVSAASKILSNITYSYKGYGLSMGTMLAGTGKGGTALYYIDSDGTRLKGDLFSVGSGSTFAYGVLDSGYRWDLSKQEALYLAQRSIVAATHRDAYSGGSVNLYHIDENGWVFHGNFDVDSLIWEAKDNENSFAHIPR
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Probable proteasome subunit beta type-5, Macropain subunit pts1, Multicatalytic endopeptidase complex subunit pts1, Proteasome component pts1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LMO7D_HUMAN
Sequence: MTWLDKGVWTQEDENSCSFSESDFPGCRDQINPSIPSIWTAVSGMMISLEVRWWIKGKQGYVISLGHALSPRLECSGTFSAHCILGLPGGSSYPPASVSQVVGTTALYLVEEAWAEAGKMRS
What are the official names of this protein?
LMO7 downstream neighbor protein.
Protein: MNME_COXBR
Sequence: MTYVFPETIAAQATPSGRGGIGVVRVSGEKTKAIAQKILGCVPKPRYATFVKFRDSGSVIDEGIALYFPKPNSFTGEDVLELHGHGGPVVMDRLLNTVLKAGARQARPGEFSERAFLNNKIDLAQAEAVADLINASSEQAARSAMRSLQGEFSKRIHQLVDALIQLRMYIEASIDFPEEEIDFLADERIKETLENLTHQVQEIEKTAKQGALLREGITVVIAGEPNVGKSSLLNLLSGQETAIVTDIAGTTRDIIRESIHIDGLPIHVVDTAGLRLTEDVVEKEGVRRTQKAVQQADLLLLMIDASKPTEDFKKIIAQWFSENDNKIPTLIVENKIDLIGEAPRKENKEYPHIKLSVKTRAGVELLKNHLKNTAGFEATHENNFIARRRHCDAIARASAFLKNANNHLLNQKAGELVAEDLKLAQNALSEITGEFTSDDLLGKIFSEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYS_ARGIR
Sequence: MNIDFSDPDFQYLAVDRKKLMKEQTAAFDGKKNCWVPDEKEGFASAEIQSSKGDEITVKIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYTYSGLFCIAVNPYRRLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKVACAVKKKDEEASDKKEGSLEDQIIQANPVLEAYGNAKTTRNNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSNAIPELNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQNMNQVVNSVGALAKSLYDRMFNWLVRRVNKTLDTKAKRNYYIGVLDIAGFEIFDFNSFEQLCINYTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGWLEKNKDPINENVVALLGASKEPLVAELFKAPEEPAGGGKKKKGKSSAFQTISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICRKGFPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRSSVSVQRSSVSVSASN
What is the function of this protein?
Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
What are the official names of this protein?
Myosin heavy chain, striated muscle.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.