PharMolix/UniProtQA huggingface dataset:
Protein: CLPP3_SYNS9
Sequence: MPIGTPSVPYRLPGSQMERWVDIYTRLGVERILFLGSEVNDGIANSLVAQMLYLDSEDSSKPIYLYINSPGGSVTAGLAIYDTIQYVKSEVVTICVGLAASMGAFLLAAGTKGKRVALPHSRIMIHQPLGGTSRRQASDIEIEAREILRMKDMLNHSLADMSGQTFEKIEKDTDRDYFLSAEEAMAYGLIDRVISHPTEA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_METEP
Sequence: MAAKIKKGDTVVVLTGRDAGRSGEVIQVMPKEDKAFVRGVNLVKKHQRQTQNQEGGIISKEAAIQLSNIAVADANGKPTRVGFRILDDGRKVRFAKTTGDQIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CPSF5_HUMAN
Sequence: MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs (PubMed:9659921, PubMed:8626397, PubMed:14690600, PubMed:15937220, PubMed:17024186, PubMed:17098938, PubMed:29276085).  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals) (PubMed:9659921, PubMed:8626397, PubMed:14690600, PubMed:17024186).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation (PubMed:17098938, PubMed:23187700, PubMed:29276085).  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs (PubMed:17098938, PubMed:20695905, PubMed:29276085).  NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7 (PubMed:29276085).  Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing (PubMed:8626397, PubMed:14690600, PubMed:15169763, PubMed:17024186, PubMed:22813749, PubMed:20479262).  The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA (PubMed:20479262, PubMed:21295486).  Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function (By similarity).  Binds to chromatin (By similarity).  Binds to, but does not hydrolyze mono- and di-adenosine nucleotides (PubMed:18445629).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor 25 kDa subunit, CPSF 25 kDa subunit, Cleavage factor Im complex 25 kDa subunit, CFIm25, Nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21, Nudix hydrolase 21, Pre-mRNA cleavage factor Im 68 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. CPSF5 subfamily.
Protein: NDHK_ACOCL
Sequence: MNSIEFPLLDRTTPNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKLSREISEDRMGSQRENRCFTTNHKFYVRRSTHTGNYDQGLLYQSPPTAEIPSETEPFFKYKSSVSSRELGNESGKEDVSIQNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MGSA_BURCJ
Sequence: MSKPRIALIAHDAKKDEIVALAGQYRETLAQCRLVATGTTGGRIAAAHGLEVERKLSGPLGGDLQIGAELADGRVDIVVFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARMLLDDLARNMQDVC
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: FABZ_PSEU2
Sequence: MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVLIIEAMAQAAGILAFKMLDSKPSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQIWKFECKATVDGKAVCSAEIICAERKL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_PECCP
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEFFEARRAELEAKLADVLAAAEARAAKIKELGSVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDIAKSEVRLPNGVLRTLGEHEVSFQVHSDVFAELNVVVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: URK_STRA5
Sequence: MRKKPIIIGVTGGSGGGKTSVSRAILSNFPDQKITMIEHDSYYKDQSHLTFEERVKTNYDHPLAFDTNLMIEQLNELIEGRPVDIPVYDYTKHTRSDRTIRQEPQDVIIVEGILVLEDQRLRDLMDIKLFVDTDDDIRIIRRIKRDMEERDRSLDSIIEQYTEVVKPMYHQFIEPTKRYADIVIPEGVSNIVAIDLINTKVASILNEAK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFRB_GEOSK
Sequence: MAQVVFSSWGRTIVDNRKGGEAQDVSFRLPTTLDGERQIAAFMGWDGIILYDLKVDVPAMAAEYMKRVQTQYCCGKCTPGKKGTKVLADVLAAIIEGRATEADLDTIDDLADLLTNCKCTLCQSSTIPVLDAVKHFREDFLAYITGIRKPANVHRFIDKYTAPCMDRCPAHIDIPAYIEAIKEYRFDESLDIIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSVNIMVLKRSASDYEWMHNAAPPMQPKPQKNKKVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPPYRQPRHLLQRDIDIISSMGVDIIYDTRIGKDISLEELKQKFDAVFLAPGAHRSKPMGVEGEDKGYKGFLKGGIDFLREAYMGRPTGMGKKVVVVGGGNTAIDCVRVALREGAEESTLLYRRSRKEMPADVWEVDGADEEGVRFEFQVLPTRVLVDENEQVTGVECVRMALGEPDASGRRRPEPVPGSEFVVECDTVIPAIGQDPDLSFIPDNLGIDITKWNTVVTKYVPLKDAAGKDLKDGMGNPLARVLITDLEGVFAGGDAEIGPLTVVACIGNAHRAARVIQRWLEEGKAYLTEDELMEDILTNMPVYDKNEKVPWLDSRERAHQAEVHGQERASKGNYQEVELGFVDTQAVEEAERCLRCYRVAMAAI
What is the function of this protein?
Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates.  May serve as a major route for NADP regeneration.
What are the official names of this protein?
NADPH-Fe(3+) oxidoreductase subunit beta, Soluble Fe(3+) reductase beta subunit.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PTNC_ECOL6
Sequence: MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLGDMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPLAAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVALSVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAAFTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ManXYZ PTS system is involved in mannose transport.
What are the official names of this protein?
PTS system mannose-specific EIIC component, EII-P-Man, EIIC-Man, Mannose permease IIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_BUCA5
Sequence: MGKIIGIDLGTTNSCVAIMDGNKPRVLENAEGDRTTPSIIAYTQEGEVLVGQPAKRQAITNPKNTLFAIKRLIGRKFKDDEVQRDIKIMPYNIVNSDNGDAWIDVKKQKMAPPQISAEVLKKMKKTAEDYLGETIKEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGKGNRTIAVYDLGGGTFDISIIEIDEVDKEKTFEVLATNGDTHLGGEDFDSRLINYLVTEFKKEQGIDLRNDPLSMQRLKESAEKAKIELSSAQQTDVNLPYITADSNGPKHLNIKVTRAKLESLVEDLILRSIEPLKVALKDAGLSVTDINDVILVGGQTRMPMVQSKVADFFGKEPRKDVNPDEAVAVGAAVQGGVLSGDVKDVLLLDVTPLSLGIETMGGIMTSLINKNTTIPTKHSQIFSTAEDNQSAVTIHVLQGERKRSSDNKSLGQFNLDGINPAPRGTAQIEVTFDIDSDGILHVSAKDKKTGKEQKITIKASSGLNEEEIKKMVNDAEANSEADQKFEELIQTRNQGDQLVHSIKKQLNENKNSIEEESKKDIQLALNKLENALKGEDKSDIEKNIQNLLKISSKLTEINQKKSEKDQKDNNMSANKKDENVVDAEFEEIKDPKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HIS1_COREF
Sequence: MLKIAVPNKGSLSERAMEILNEAGYAGRGDSKSLNVLDSANDVEFFYLRPKDIAIYVAGGQLDLGITGRDLAADSRADVHEVLSLGFGSSTFRYAAPAGQGWSIEKLEGKRIATSYPNLVRDDLAARGITAEVIRLDGAVEISIKLGVADAIADVVSTGRTLRQQGLEPFGESLCTSEAVIVGRRDEEITPAQRVLLSRIQGILHAQNYLMLDYNVDRDRLDEASAVTPGISGPTVSPLARENWVAVRAMVPLKSANATMDKLASIGAEAILASEIRIARI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_HELPG
Sequence: MARIAGVDLPKKKRVEYALTYIYGIGLKSSREILEAVGISFDKRVHELSEDEVSSIAKKIQQSYLVEGDLRKKVQMDIKSLMDLGNYRGIRHRKGLPVRGQTTKNNARTRKGKKKTVGSK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IRE1_YEAST
Sequence: MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGASYNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENYEKTNSLDTTHKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGKQVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPNFEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS
What is the function of this protein?
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation.  The active endoribonuclease domain splices HAC1 precursor mRNA to produce the mature form which then induces transcription of UPR target genes.
What are the official names of this protein?
Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: EXPL8_DICDI
Sequence: MRISIILLSLLFLSLHSLIKADITKLSVCGSARAVPTATQNPKPTCVNVNSQGIPTAGLNSAAFDNGVRCGQCYELTGPLGKTVVMVADVCDAGSACTQSDLFNFIIPNEEFDKIGNRSDYGNIFSLCYQIVSCGYSGNVQGVFTGPSSSPNTFTYFLSVVFSNNNVAIKKVLIKGLSWPLYESLTGQNGNWKWNKNSYELQFPATLYITSNTGETITYKMNSRPITNQPIDLDFQFNPKAISSLENNECSMALLPQYIYQDGLSYGWVDSQSFNYAKFTDKSSDTKSGSGTCINAQLDGHGGVKFTREGDFQTSYLDKLSFDIKTSADSSSFAVYFGDVATKNIDPLVASTWTTVELSVKSLTNNTVEGSITFFNNQADPINIWLDNIKWTYTDDAPLDQPTMDLIEVNNKPSTTSGTGTTSSKPSSSSGGVSGGGIGSESSIYGLSSENQENQSGHHASSNTNILLPTTFVFFISITILSLLF
What is the function of this protein?
May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
What are the official names of this protein?
Expansin-like protein 8, Ddexpl8.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LOLA_SHEB5
Sequence: MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYM_CORU7
Sequence: MSKRVLTSVAWPYANGPRHIGHVAGFGVPSDVFARYQRMIGNDVLMVSGTDEHGTPLLVQADKENTTVRELADRYNRIIVEDLVGLGLSYDLFTRTTTRNHYAIVQELFRGLNENGYMLKQTTRGAVSPSTGRTLPDRYIEGTCPLCGATDARGDQCDNCGNQLDPADLIDPRSKINGETPEFVDTEHFMLDLPALAEALEEWLKGRNDWRPNVLKFSLNLLKDIRPRAMSRDIDWGVPVPIEGWQDNNAKKLYVWFDAVVGYLSASIEWAWRTGDPEAWRKWWNDPEAVSYYFMGKDNITFHSQIWPGEMLGYAGKGSKGGEQGELGELNLPTEVVSSEFLTMSGSKFSSSKGVVIYVRDFLKEFGPDALRYFIAVAGPENTDTDFTWDEFVRRINSELANEWGNLVNRTASMAHKNFGEIPQPGEFTAEDQALLDEAKQAYTVVGDALQLSKFKAGMTEAMRIAARANQYIAAQEPWKLAKDETQRERLATVLYVALQVVSDVNTLMTPYLPFSAQKVFETLGGEGIWAAQPEIVEVKDESPYTPVGVGLPEEGSSYPVIMGNYTEQKAIWQRTELAPGTALSKPKPLFQKLDPELAETGPEWAPVVKD
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_STAAC
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMAYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRNLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIA1_USTMD
Sequence: MRFAGMSCDDERPANMFDLMAPQLASTSCNEHYFSTADLGASTLYATTTDAPATIAGILTPQPATLAPMYSTCPVRFDDQRSAPASTSVSGKRKHSDVEKDRRRSISNGFAVLQNVLHNESNAKPISKSILLQQACDEIRELRKKLDASTTIISRFGLENLFVPTPSSTHASPPNASSRIYSPINQASDVLADTRRASISTSATPILYSEEKRKANAKRRHSYDGSWQASDRGSIDDEASASASASASASSSASCSSSSHTHSDDTDCDDTDTDIPAESALKERTKRHKARSKKERDRTKPRYRPKPSTNRSPTPSSCASSTPNSPPTSSNRNRDLQQAILSLLLELPSHLEDVKNKRRASQPTELADPSSVKSRSKKRHR
What is the function of this protein?
Transcription factor that specifically regulates the expression of the gene cluster that mediates the biosynthesis of itaconic acid and 2-hydroxyparaconate (PubMed:26639528).
What are the official names of this protein?
Regulator of itaconic acid biosynthesis, Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein RIA1.
What are the subcellular locations of this protein?
Nucleus.
Protein: C89A2_ARATH
Sequence: MEIWLLILASLSGSLLLHLLLRRRNSSSPPLPPDPNFLPFLGTLQWLREGLGGLESYLRSVHHRLGPIVTLRITSRPAIFVADRSLTHEALVLNGAVYADRPPPAVISKIVDEHNISSGSYGATWRLLRRNITSEILHPSRVRSYSHARHWVLEILFERFRNHGGEEPIVLIHHLHYAMFALLVLMCFGDKLDEKQIKEVEFIQRLQLLSLTKFNIFNIWPKFTKLILRKRWQEFLQIRRQQRDVLLPLIRARRKIVEERKRSEQEDKKDYVQSYVDTLLDLELPEENRKLNEEDIMNLCSEFLTAGTDTTATALQWIMANLVKYPEIQERLHEEIKSVVGEEAKEVEEEDVEKMPYLKAVVLEGLRRHPPGHFLLPHSVTEDTVLGGYKVPKNGTINFMVAEIGRDPVEWEEPMAFKPERFMGEEEAVDLTGSRGIKMMPFGAGRRICPGIGLAMLHLEYYVANMVREFQWKEVQGHEVDLTEKLEFTVVMKHPLKALAVPRRCH
What are the official names of this protein?
Cytochrome P450 89A2, ATH 6-1, CYPLXXXIX.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DAPF_PHOV8
Sequence: MATTIKFTKMQGTGNDYIYVNTLSSPLQDPIKAARKWSTYHTGIGADGLVLIGASEKADFSMRIFNADGSEAMMCGNASRCIGKYVYEKGLTDKEVITLETLSGIKILKLHTGNGVVKDVTVDMGTPLLSNPGQIATKTGGMLAETIPADGKEYKGTFVCMGNPHVVIFVDDIKEVDLPAVGPKLENHPLFPERTNVEFVEILPDQSLRMRVWERGSGITMACGTGACATAVAAVLNHKAGRKSWVRMDGGDLHIHWNEKDGHVYMTGPAGKVFEGEIEM
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_VIBC1
Sequence: MSAIDKHAVKQFLMSLQDSICQQLEQEDGKAVFVEDAWQREKGERLGGGGRTRVLRDGHIFEQGGVNFSHVEGNEMPASATAHRPELAGRRFEAMGVSLVIHPKNPYVPTSHANVRFFIAEKDGEDPIWWFGGGFDLTPFYPFDEDCQSWHDTAKQLCAPFGDEVYPEHKAWCDKYFFLPHRNETRGVGGLFFDDLNQWEFDKCFDYIKAVGEGYCQAYLPIVSRRKDIEFGEREREFQLYRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSMPPLARWEYSYEPQTGSPEAELYERYLTPREW
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBG1_XENLA
Sequence: MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYANLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSHVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTNISSLFERTCRQYDKLRKREAFLEQFRKEDIFKDNFDELDNSREIVQQLIDEYHAATRPDYISWGTQDK
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-1 chain, Gamma-1-tubulin, xGAM.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to mitotic spindle microtubules.
Protein: VME1_CVHNL
Sequence: MSNSSVPLLEVYVHLRNWNFSWNLILTLFIVVLQYGHYKYSRLLYGLKMSVLWCLWPLVLALSIFDCFVNFNVDWVFFGFSILMSIITLCLWVMYFVNSFRLWRRVKTFWAFNPETNAIISLQVYGHNYYLPVMAAPTGVTLTLLSGVLLVDGHKIATRVQVGQLPKYVIVATPSTTIVCDRVGRSVNETSQTGWAFYVRAKHGDFSGVASQEGVLSEREKLLHLI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: MBLC2_MOUSE
Sequence: MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGSKEDAGRRPLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNPRTSP
What is the function of this protein?
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.  Has an acyl-CoA thioesterase activity towards the long chain fatty acyl-CoA thioester palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA).  Displays a substrate preference for fatty acyl-CoAs with chain-lengths C12-C18.
What are the official names of this protein?
Acyl-coenzyme A thioesterase MBLAC2, Acyl-CoA thioesterase MBLAC2, Beta-lactamase MBLAC2, Metallo-beta-lactamase domain-containing protein 2, Palmitoyl-coenzyme A thioesterase MBLAC2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor.