PharMolix/UniProtQA huggingface dataset:
Protein: HORM2_HUMAN
Sequence: MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGERHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMYQFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVLTMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVKVFIPNRK
What is the function of this protein?
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.  Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
What are the official names of this protein?
HORMA domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes (By similarity).
Protein: RS3_CERS1
Sequence: MGQKVNPIGMRLQVNRTWDSRWFAESKDYGNLLLEDLKMREFIHDYAKQAGVSKVIIERPHRKCRVTIHTARPGVIIGKKGADIETLRKKLSAFTKSELHLNIVEIRKPELDAQLVAESIAQQMERRVSFRRAMKRGVQNAMRIGALGIRVNVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATSEATTPYGIIGVKVWIFKGEILEHDPQAHDRRHSEAQEGAAPRPPRRDRERA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: UBQ14_ARATH
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGF
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin 14.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPB_PSET1
Sequence: MTKNKIGVFGANGRMGSALLEAASTKEHSELAAAYVRSSSPLLGINVNQLNSAADKTVTFSDEANITNVDVLIDFTLPAGMRTHLQTAVKQGVPMVIGTTGLNEADMTLLHEAANHIPIVFARNYSVGVNVLLNLVQTAATKFGDDMDIEIFEAHHRHKIDAPSGTALAIGEAIADAKGWDHDKVAVYDRSKVEQAKSQNEIGYSVLRGGDIVGEHTAYFATMGERLELTHKASSRMTFALGAIRAAGWLINKPAGLYDMQDVLDLK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXE_ECOL5
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPSEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAAAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATC_BACC4
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: KBAA_BACSU
Sequence: MKSRGLVRFFFSILAVGALITSIVGFALKWGEYRGLFLTFEAGQIFSVLFWFIGVGMIFSVISQMGFFVFLTVHRFALEILRSSSLWNLLQLFFILFVAFDLMYVRFLFFGESGESLAGYAWLPVFLLIFGVITAYIKQKQSSKKTFVSSLFLMVVITALEWFPALRVNDEDWLYLMLFPLMACNAFQLLMLPKFAAK
What is the function of this protein?
Involved in the activation of the KinB signaling pathway of sporulation.
What are the official names of this protein?
KinB-signaling pathway activation protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDPA_RHOE4
Sequence: MSPALAAGLQIAFVLAVLAIAYVPVGDYMARVYSSTRDLRVESVIYRVGRIDSRAEQTWYGYAASVLGFSLASALFLYFLQRIQGVLPLSDGLSGVSPAVAFNTAISFVANTNWQSYTPETTMSNFVQPVGLAVQNFVSAAVGMAVAIALVRGFIRVARGGEIGNFWVDLTRGSLRILLPFSFVIALILLSQGVIQSFHSGFASTGLDGNAVTNALAPVASQEAIKELGTNGGGILAANSAHPFENPTPLSNIVEILAILLIPVCLTRTFGTLVGDRRQGLTLLAVMGILWSGLLAVTLAAESGARGVAATAAGSMMEGKEVRFGIPGSALFAVATTGTSTGAVNSAHDSMSPLGGGAVLLNMLLGEIAPGGVGTGLYGILVLALIAVFVGGLLVGRTPEYLGKKLGRREITLAALSILVMPALVLIGTAITVILGSTTGYQGNGGDPGTPGSIHGFSEVLYAFASASNNNGSAFGGLTVTSDWFQSSLGICMLLGRFLPIIFVLALAGALASQKKVAPTAGTLPTSGPMFTGLLTGTVVLVAALTFFPALALGPLAEALQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AAEX_YERPB
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM171_MOUSE
Sequence: MSSVGTAEPDGDQRDRHVSKLIFFLFVFGAALLCVGVLLSIFGYQACQYKPLSHCSIVLKIAGPSCAVVGLGAVILARSRARLHLRERQRQGLQDPDQSFFCGESRQFAQCLIFGFLFLTSGMLISILGIWVPGCDSDWAQEPLNETNTGEGEPQICGFLSLQIMGPLVVLVGLCFFVVAHVKKKNNLSSSRDTSEVEGGHAHSTEPVHITVGDSVIIFPPPPPPYFPESSAAAPSPGANSLHQIENPPSYSSLFNYGTPTPENQGAASEREQELIYTISGQGSSSERSYTGHLPLDLPPRYEEKETAPATPLGAPSDASPP
What are the official names of this protein?
Transmembrane protein 171.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOK1_GEODF
Sequence: MLALNNYLIISAILFSIGTIGVLVRRNAIVIFMCVEMMLNAVNLTFIAFSKYLGNIDGQIFVFFVMTVAAAEAAVGLALMIAFFKNRESIDVEDVNIMKW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_CHLPD
Sequence: MANINFGFEHHARKLYSGAIEQGITGSLVPMVIETSGRGERAFDIFSRLLRERIIFLGSGIDEHVAGLIMAQLIFLESEDPERDIYIYVNSPGGSVSAGLGIYDTMQYIRPDVSTVCVGMAASMGAFLLASGTKGKRASLPHSRIMIHQPSGGAQGQESDIIIQAREIEKIRRLLEEILASHTGKDVQQVREDSERDRWMNAQEALEYGIIDQIFEKRPKPDKEKES
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_NITEC
Sequence: MLSPVRITVTGAAGQISYSLLFRIAAGDMLGSNQPVILQLLDIPESRKILDGVVMELQDCAFPLLAGIIATHDPMMAFDQTDIAILVGARPRRKGMERKDLLQTNGEIFRNQGKILNQVAKRDAKILVVGNPANTNTLITMKNAPDLPAENFSGMLRLDHNRALSQVAMKLNQPVSNIKKMIVWGNHSSTQFPDLYHAEIGDTKVINLIKDPIWIENYFIPTVQKRGAVVIEARGLSSAASAANAIIDHLRNWFFGTADGDWTTMGILSDGSYEIPEGVIYGFPVICKNGMREIVQGLEINPFSRTRLDAAYNELTQELDSIRHLLP
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: Y1740_YERPE
Sequence: MLDTNMSAFGVASIALPLLTVLFFLIVWFFLSRASVRANEQVRLLREIAEQQKRQTELLTALLENATGTRDGQNDSDTVSPLDFKGFIPER
What are the official names of this protein?
Uncharacterized protein YPO1740/y2567/YP_1481.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YS97_CAEEL
Sequence: MLIPSPDPFASCPGYYLPDFEPFKACTNISNFCNHARDVYNIEMLLRWAIFIIPCCMSFFALFLNIYIFYVLIPNLRKMNGRSKKKYIFILSRAVSASMSILAIFLLPVIIFLTHFNFWVIALFIIFEMLSFLSFIGGMVGTTLTIYIAVVHPMYYQRELSLRKCVLLILLLWVSAITVAISCGIVEAAFIGRNSPFSCDYGNCAGPVLIFGIVCIATAFSICLVIQLYVIISLWKLGIQSTKRGDYSSTSKALTGVKRKLFAGFFVFATMAIFEIASAIILVRSVSEQTQDLDACDKLSASTSRLQFVISCVVLTLLW
What are the official names of this protein?
Putative G-protein coupled receptor B0244.7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. B0244 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDD_BURP1
Sequence: MQTVLIALLRFYKLAVSPLLGSRCRFYPSCSDYAREAIQYHGAARGTYLAARRLCRCHPFSAGGVDLVPPPNSDARNAPHEAEASSHRL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PURL_BACLD
Sequence: MSLLLEPSQEQIKEEKLYQQMGVSDDEFAMIESILGRLPNYTEIGIFSVMWSEHCSYKNSKPILKKFPTKGERVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIAVLNSLRFGELTSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDGCYEGNPLVNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDQSEEKRSAVQVGDPFMEKLLLEACLEVIKSDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRETGMTPYEMMLSESQERMLLVIERGREQEIIDIFDKYDLEAVAVGHVTDDKMLRLFHNGEMVAELPVDALAEEAPVYHKPSKVPDYYKEFLETDVPAPKVEDAKETLLELLKQPTIASKEWVYDQYDYMVRTNTVVAPGSDAAVLRIRGTKKALAMTTDCNARYLYLDPETGGKIAVAEAARNIVCSGAEPLAVTDNLNFGNPEKPEIFWQIEKAADGISEACNVLSTPVIGGNVSLYNESNGSAIYPTPVIGMVGLIEDTEHITTQHFKAAGDLIYVIGETFPEFAGSELQKLTEGKIYGKAPAIDLEVEQSRQKALLKAIRSGLVQSAHDVSEGGIGVALAESVISSQRLGAHVTLAGEPALLFSETQSRFIVSVKKDHQEAFEKLVKDADLIGEVTSDSVLAVQSQEGQQWIHAQTEELESAWKGAIPCLLKSKA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHB13_MOUSE
Sequence: MNLILEFLLLVGVIIYSYLESLVKFFIPRRRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLGAVVHVFVVDCSNRAEIYNSVDQVKREVGDVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLCPVFVNTGFTKNPSTRLWPVLEPEEVARSLINGILTNKKMIFVPSYINISLILEKGPGFSSKHPHGGSQQPVTPIPGDLTPSSDFLKH
What is the function of this protein?
Plays a pivotal role in hepatic lipid metabolism.  In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4.
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, Alcohol dehydrogenase PAN1B-like, Hepatic retinol/retinal dehydrogenase, Short-chain dehydrogenase/reductase 9.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation.
Protein: RCN2_RAT
Sequence: MRLGPRPAVLGLLLLLLLYAAVAGASKAEELHYPQGEHRADYDRETLLGVQEDVDEYVKLGHEEQQRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGTVTWDEYNVQMYDRVIDFDENTALDDTEEESFRQLHLKDKKRFEKANQDSGPGLNLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDSDGRLDPQELLSWVVPNNQGIAQEEALHLIDEMDLNSDKKLSEEEILENQDLFLTSEATDYGRQLHDDYFYHDEL
What is the function of this protein?
Not known.  Binds calcium.
What are the official names of this protein?
Reticulocalbin-2, Calcium-binding protein ERC-55, Taipoxin-associated calcium-binding protein 49, TCBP-49.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: SEM3C_PONAB
Sequence: MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPVHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES
What is the function of this protein?
Binds to plexin family members and plays an important role in the regulation of developmental processes.  Required for normal cardiovascular development during embryogenesis.  Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
What are the official names of this protein?
Semaphorin-3C.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_SHEB2
Sequence: MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTLEIPRKRGRQKTTG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RUTF_ECOKI
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMELRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: Y5800_ARATH
Sequence: MVKNKAFFGQIMEERDNPAFFKILRREDHSTEMMRMIPHHLIRSISDKSSSFKMVLRVPWGRSWQVKISKNPNFHYMEDRGWNQFVNDNGLGENEYLTFTHEANMCFNVTIFEADGTEMLRPRKTITSSSGRNKREERKSIYKDVKKEEEIESWSESSHPCHKTAESTSGRLTQKQELNLRKKEADKTEKSKTSKKKKVETVSNDSEAGTSSLIPEFKLTIKKSHLLFLGIPKKFVDMHMPTETTMFKIHYPRGKKSWDVTYVVTDVQSRFSGGWSRLAKELGLLVGDVCTFKLIKPTEMRVKVSKE
What are the official names of this protein?
B3 domain-containing protein At5g18000.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDPA_PHOLL
Sequence: MSLQIDQIALHQLIKRDEQTLDVVLRDSLLATDQVVEDMMAELHRVYSAKSKAYGLFNEESELAEALRHQRKGDEDFLGFSRAATARLRDELAKYPFAEGGTVLFCQYRYLAVEYLLIAVLNSCNSMSVNDNLDLNTTHYLDIPHADIVARIDLTEWETNPESSRYLTFLKGRVGRKVSDFFMDFLAASEGMNAKVQNKGLLQAVDDYCESGELNKDERQAYRQQVYNYCNEQLQAGEEIEIKALSQALPTFGEQNFQQFSQEQEYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLFGERIFWDPATDTLTIKGTPPNLRDQLQRRSSGH
What are the official names of this protein?
Nucleoid-associated protein plu2870.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: EFTS_RHIWR
Sequence: MAEITAAAVKELREKSGAGMMDCKKALTETNGDMEAAVDWLRTKGLATAAKKSSRTAAEGLVGVSVEGTKGAAVEVNSETDFVAKNDQFQDFVRTVTQLALTAGDDVAALAGAGYPGGGTVAEKLTSNIATIGENQTLRRAKVVEVSKGTVVPYVHNAAVPGLGKIGVLVALEGDAPVAEMETVGKQIAMHIAAAFPQALTEDGLDPVVIERERAIAAEKAAESGKPAEIVEKMVQGAVAKFRKENALLSQVFVIDNKTPIAQVVANAAKAAGGSITLKDYVRFQLGEGIEKETSDFAAEVAAAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FARP_ARTTR
Sequence: RYIRF
What are the official names of this protein?
FMRFamide-like neuropeptide RYIRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
Protein: HUTG_PHOLL
Sequence: MNLWHATSPTIWQGRNDLAEADNALRLFQTVKLSPYFTPEEFSHYVALLGFECDEGVKRNQGRPGANQGPDYLRQSLANMASHKGHDKLVDLGSIRANPNQLSEAQQALSDAVTQCQCQNVRTLVLGGGHETAFAHGVGIYDAFPHQRVGIINFDAHLDLRRSPQPTSGTPFRQLAEYCQQHQRLFHYTCIGASLASNTQALVDEANRLNATIIWDNQCRETMLDKVQQQIQDILQQVDLIYMTIDLDVLPAYQMPAVSAPAALGLPLERLLQLIQPICQSGKLQAADLVELNPLFDIQGIGGRAAARLAWQLAHWWY
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: LY66F_BOVIN
Sequence: MAVLFLLLLFLCGLPQAETDSIQAIYVVLGEALELPCPSPPALNGDEFLSWFHSPAAGSSTALVAHVQVARPSRDPGKPRRESRLTLLGNYSLWLEGSKAGDAGRYWCALLGQRYRYQNWRVYDVSVLRGSQFSARAADGSSCSVLLCSVVPARSLDSVTWQEGKGPVKGDVQSFWGDGATLLLMCPGEGLPEPRAHKPGIIRCLVPQNKGISFSLAASTDASPALCAPSADWDVAWILTLLLTVGQGFTIVVLGVMLWRQRAQGAQHRNASFPQFKPEIQVYENIHLAHLSPPAPKTR
What is the function of this protein?
May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G6f.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RUVC_THIDA
Sequence: MRILGIDPGLRLTGFGLIEQTGQKLAYVASGVVKSGEGSLPARLGILFGGINEVIATYRPDTCAVEIVFVNVNPQSTLLLGQARGAAICAAVSNDLTVAEYTALQIKQAVVGHGKAAKTQVQEMVKRLLALPIAPTADAADALACAITHAHGSRLGAQSTAGYRLKGGRLV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.