PharMolix/UniProtQA huggingface dataset:
Protein: ACRBP_RAT
Sequence: MKLAASFLLMLLEVLLLPETPLSAEEALASTPGSPLSSTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSDLPYASWFESFCQFAQYRCSNHVYYAKRVRCSQPVSILSPNTLKEVESSAEVPLTSVTTPIVSRATATEHQAFQPWPERLNNNVEELLQSSLSLGGKEQQSSRKLGLEQQHKQEQIQEHKLEEAQEQEEQEEEEEEEEAKQEEGQGTEEGLDSVSRLQSDSEPKFQSKSLSSNPSFFTPRVREVESAPLMMENIQELIRSAQEMDEMNELYDDSWRSQSTGSLQQLPHTETLMVLCYSIMENTCTMTPTAKAWSYMEEEILGFGDSVCDNLGRRHTAACPLCAFCSLKLEQCHSEASVLRQQCDASHKIPFISPLLSAQSISTGNQAKIPEKGRFAGLEMYGGLSSEFWCNRLALKGCEDDRVANWLKAEFLSFQDGDLPTKICDTNYVQYPNYCSFKSQQCLLKNQNRKMSRMKCMLNEKYHVLSPAKGEEVILRWSQEFNTLTLGQFG
What is the function of this protein?
Rodent specific isoform that participates in the formation of the acrosomal granule into the center of the acrosomal vesicle during early spermiogenesis.  In the fertilization process promotes ACR release from the acrosome during acrosomal exocytosis.
What are the official names of this protein?
Acrosin-binding protein, Acrosin-binding protein, 60 kDa form, Proacrosin-binding protein sp32.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Colocalized with pro-ACR in the acrosomal granules of early round spermatids. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Highly enriched in acrosomal granules of round spermatids, and spread over the apical end of the nucleus in elongating spermatids. Colocalized in the acrosome of epididymal sperm with pro-ACR.
Protein: NRDR_METFK
Sequence: MKCPFCGADDTQVIDSRVNEEGDSIRRRRRCNACDKRFTTYETAELHLPQVVKQNGKREEFNRDKLRLSFTRPLHKRPVPTEYVDRALEHIVQKILAKGEREIMARDLGEIVMQELKAIDKVAYIRFASVYRSFQDVDDFNDVIRDLD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL30_SHEHH
Sequence: MATKTLKVTQTKSSIGRLPKHRASLLGLGLRRINHTVEVEDTPSVRGMINKVYYMVSVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: YT15_STRFR
Sequence: MVKPPLRCQGGQVARGHRALSIALKTEDLVGGLSITKDRGDRDDGRYGEPRIQRKPGQLTANDPVAYDFVRHVASVSTRDLKVGVVDGQRIPVRFAHDKSAAWAKDTPGLCKCLGRVRHVLEHAVGPGTVDAAVLERERVDIA
What are the official names of this protein?
Uncharacterized 15.5 kDa protein in transposon Tn4556.
Protein: YKP5_KLULA
Sequence: MIYDKIDTKLIKLGKTNKFSGEEEKSITSLYYEDESFEFSFKNKYVKITKIETNAYGKKFVTIKSKLYADIVEKVAKELDAVSPILSDGSFRATINDATSFSKDVGEYSFYACVSLYFPSIYKDTEKTTLQVYLKEVVVTKIIKNNLEVEFDKLSLAI
What is the function of this protein?
The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains.
What are the official names of this protein?
Uncharacterized killer plasmid pGKl-2 protein 5.
Protein: RL1_MYCPU
Sequence: MAKIGKKLQEAKKLVDKNQFYPLIEAIQLAKKTSYSKFDASIDLAFRLNLDTRKADQQLRGSILLPHGNGKVTRVLVATDSPELQKSSKEAGADFVVDKLELEEIIKQNKFDFDVIVADPKMMPILGRYGKVLGPKGLMPNPKTGTVTPNPDKAVVEIKKGKANYRADKYGIVHSLIGKKSMSDDQLLDNAKVLIDTIKRLKPSVVKGTYIKNLTISSSMGPSIKIKLD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YCDX_SALEP
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDRILNVSPQRLLAFLESRGMAPVPEFAEL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: AROB_MACCJ
Sequence: MKLTTNYNDNNYDIFVEYNVLNKDYDFNYYDKRIALIDESVYRLHQQKIDLFLNKHSIFKLLIPGGEQVKTMHHYSTVVEKLLSMHVTRHSCLFAIGGGATGDFTGFVAATLLRGIHFIQVPTTILAHDASIGGKTGINASSGKNLIGAFKRPDMVLYDLDFLETLSQIEKLSGFAEIIKHVLLNANGHISKSETVLEIMHDVKDEVCLSELHAIDKWITFGIQTKMKVVHDDEFESGVRKFLNFGHTFGHAIEFHHKLPHGIAVMHGMIYALLLSDVTESDIMSLMRWMHRLGLKKLVYDNFDIYYELMRQDKKNEANEINFVLYYENNGYKVEQVDVKRLRKAFERLRKLEGELL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_TRES6
Sequence: MNRQDIGFVQSSINYQFKNLQLLEQAFTRKSYSEEHPELQNNEVLEFYGDEILDFFVTKMMYKRFSRILNNELVSEKNEGELTKLKSILVSKESLARCMYNIGFSKFLYLGKSDEKNEVYKSKSVNEDLFEAIIGAVAADCDWNYEKLEKVCRTMLDMETTNGYLALLVKEKSHRLGFGEPCYRPFAWQTDNPEDWQSDNLFNMGIGFGGFGSTSKNPKTGKHEYGIQVGENKFTGIGDGIAQAKLNAEQKAYHFLIQEEIKQQFQNLDYTNPASTLHELFQKKVIMEVRYEFNEYHDENGNPIWNCKAILEGYGTFEADNASKKQVKQDASLKLLKFIAKTKIEQTEKWEIPTFYHGMARIWHDEGKI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRMK
Sequence: MNEVVQSPAIQPLPKSAPTAGKQNLLDLDRAGLEKFFVEVLGEKKFRAHQVMKWIHHRYVTDFDEMTDLGKVLRAKLQAHAEVLVPNIVFDKPSADGTHKWLLAMGVDGKNAIETVYIPDKTRGTLCVSSQVGCGLNCTFCSTATQGFNRNLTTAEIIGQVWVAARHLGNVPHQMRRLTNVVMMGMGEPLMNFDNVVRAMSVMRDDLGYGLANKRVTLSTSGLVPQIDRLSAESDVSLAVSLHAPNDALRETLVPLNKKYPIAELMASCARYLRANKRRESVTFEYTLMKGINDKPEHARELARLMRQFDNAVQAKDSGKVNLIPFNPFPGTRYERSEEAHIRAFQKILLDSNVLTMVRRTRGDDIDAACGQLKGQVMDRTRRQAEFNKTLQAGKGSDAAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_KLEP7
Sequence: MAQHDENVVWHAHPVTQQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHERGVSTYLLDGDNVRHGLCSDLGFSDEDRKENIRRVGEVARLMVDAGLVVLTAFISPHRAERQMVRERLGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPEKAEIHLDGEQLVTNLVHQLLDLLQQSDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: TSAC_ECOHS
Sequence: MNNNLQRDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVMRLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDVQRETIFSRWPGPVTFVFPAPATTPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGAAFPVVPGETGGRLNPSEIRDALTGELFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSW_HYDCU
Sequence: MPIRDWRQQSQRWPIDYWLIGALAILITLGLTMVASSSIAISEKRFGDPTHYLLRQMFSMGLGLMAAYIVLKIPLSFWRKHRGQLFIVGLVLLVLVLVFGREINGSKRWLPLVLMNFQVSEFMKIAVVVFMAGYLDRHATAVRESFEAVIRLALPFGVMAILLLLEPDFGSTFVIAVIITGMLLIAGAPWRFFVMTVLPIATLLVMMVITSPYRMARVTNFLDPWSDPFGNGYQLTQALIASGRGEWFGVGIGESVQKLLYLPDAHTDFLFSIYAEEYGLIGVAFLALLYLTLLYRCFRIGRKAFNQTHYFGGLIAYGVGIWIVLQAMINMGVNLGLFPTKGLTLPFMSYGGSSVLMLFIGVAMVLRVDLETRQAVLEHSVDESGQGKR
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: VSTM4_HUMAN
Sequence: MRLLALAAAALLARAPAPEVCAALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSATEMRVISLKASEESSFEKTKETWAFFEDLYVYAVLVCCVGILSILLFMLVIVWQSVFNKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPKKGKRQKEKPDIPPAVPAKAPIAPTFHKPKLLKPQRKVTLPKIAEENLTYAELELIKPHRAAKGAPTSTVYAQILFEENKL
What is the function of this protein?
Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.
What are the official names of this protein?
V-set and transmembrane domain-containing protein 4.
What are the subcellular locations of this protein?
[Peptide Lv]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: TRMY_HALS3
Sequence: MRQFVVLGHDAPTTPDFPLDDLPGAAGRLDVLCRCVSAALFVSHGIRDDVEVFLVLGDEVTVRIDAGAVQYMHPDERNVAGLLKQALDAKTEAIGHQEASSSPGIHVSKRGFEAVLDAVSGPVVALHEDGDALAAVDPLADPVFVLSDHRDFTAAEASLLADASDHRVRVGPTVLHADHAITVAHNHLDTAGFDAY
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_ALISL
Sequence: MTILFISDLHLCPTRPEITTCFLDFMENEAVHAKELYVLGDLFEFWIGDDDNSSFSSLIKNAFTTLTNQGVHCFFIQGNRDFLLNKRFCKETGITLLADHTVIDVDGKKVLIMHGDTLCIDDVKYQEFRAKVHQPWLQWIFNRIPLFIRQHIVKNVQDKIKEKKQHKTLSIMDVTQSEVERVMHEEGVNLLIHGHTHRPDTHSFTVNDNQMTRIVLGDWYTQGSILTYKDNTFTLLNKSFK
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPAT5_HUMAN
Sequence: MSSKKNRKRLNQSAENGSSLPSAASSCAEARAPSAGSDFAATSGTLTVTNLLEKVDDKIPKTFQNSLIHLGLNTMKSANICIGRPVLLTSLNGKQEVYTAWPMAGFPGGKVGLSEMAQKNVGVRPGDAIQVQPLVGAVLQAEEMDVALSDKDMEINEEELTGCILRKLDGKIVLPGNFLYCTFYGRPYKLQVLRVKGADGMILGGPQSDSDTDAQRMAFEQSSMETSSLELSLQLSQLDLEDTQIPTSRSTPYKPIDDRITNKASDVLLDVTQSPGDGSGLMLEEVTGLKCNFESAREGNEQLTEEERLLKFSIGAKCNTDTFYFISSTTRVNFTEIDKNSKEQDNQFKVTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEVEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPNLPDVKVAGLVKITLKDFLQAMNDIRPSAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALEEDIQANLIMKRHFTQALSTVTPRIPESLRRFYEDYQEKSGLHTL
What is the function of this protein?
ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024).  Acts together with SPATA5L1, C1orf109 and CINP (PubMed:35354024).  May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein SPATA5, Spermatogenesis-associated factor protein, Spermatogenesis-associated protein 5.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. AFG2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Cytoplasm, cytoskeleton, spindle.
Protein: MUTH_ECOUT
Sequence: MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWIPVEGERSIPLAKRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQIERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB7_PANTR
Sequence: MGAHLVRRYLGDASVEPDPLQMPTFPPDYGFPERKEREMVATQQEMMDAQLRLQLRDYCAHYLIRLLKCKRDSFPNFXACKQERHDWDYCEHRDYVMRMKEFERERRLLQRKKRREKKAAELAKGQGPGEVDPKVAL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, Complex I-B18, CI-B18, NADH-ubiquinone oxidoreductase B18 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB7 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: IF2_BRUC2
Sequence: MSDKTNDDKTLSVNPKKTLTLKRPGVEQSTVRQNFSHGRTKAVVVETKKRKFSRPDEKPEVEAAAAPKPAAPAAAPQQAPASAPVSASAAQASAPQPAPVKAPATKAPAAPSAPVTKPHVAQQRPVHQRPGGQQAQRPRPADRSGMVLNTLSRSEMDARRRALEEAQIREVEERARAVEEAKRRAEEDARRAKEREESARRQAEEEARLKAEAEARRKAEEEAAKRMPQPEARSERRDDARPAPYGARPQQAGRPQGGRPQPAGRPQQGSPRPAPIIADAAPIAGKPLPQSQLRKPGQSDDDDDRRSGAARRGVAAKPEVRAPKVVKGEDDRRRGKLTLTSNLEEEGRSRSLSAMRRRQEKFKRSQMQETREKISREVTIPETITLQELAQRMAERSVDIIKYLMKQGQMMKPGDVIDADTAQLIAEEFGHTVKRVAESDVEEGIFDVADNESATVSRPPVVTIMGHVDHGKTSLLDAIRHANVVSGEAGGITQHIGAYQVVQNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKPAADPQKVRTALLQHEVFVESMGGEVLDVEVSAKNKINLDKLLDAVLLQAEMLDLKADPDRTAEGVVIEAQLDRGRGSVATVLIQKGTLHPGDILVAGSEWGRVRALVNDRGEHVKEAGPAMPVEILGLQGTPQAGDRFAVVANEAKAREIAEYRQRLARDKAVARQSGARGSLEQMMNQLQVSGTKEFPLVIKGDVQGSIEAITNALDKLGTDEVRARIVHSGAGGITESDVSLAEASNAAIIGFNVRANKQARNSAEQQGIEIRYYNIIYDLIDDVKAAMSGLLSPERRETFLGNAEILEVFNITKVGKVAGCRVTEGKVERGAGVRLIRDNVVIHEGKLKTLKRFKDEVAEVPSGQECGMAFENYDDIRAGDVIEAFRVEHVSRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTY_PARSN
Sequence: MTHDVLLAGAGLANGLIALALRAARPDLRVLLLDHAAGPSDGHTWSCHDPDLSPDWLARLKPLRRANWPDQEVRFPRHARRLATGYGSLDGAALADAVVRSGAEIRWDSDIALLDAQGATLSCGTRIEAGAVLDGRGAQPSRHLTVGFQKFVGVEIETDRPHGVPRPMIMDATVTQQDGYRFIYLLPFSPTRILIEDTRYSDGGDLDDDALAAASHDYARQQGWTGAEVRRERGILPIALAHDAAGFWADHAAGPVPVGLRAGFFHPVTGYSLPYAAQVADVVAGLSGPPGTDALRGAIRDYAIDRARRDRFLRLLNRMLFRGCAPDRRYTLLQRFYRMPHGLIERFYAGRLSVADQLRIVTGKPPIPLGTAIRCLPERPLLKENA
What is the function of this protein?
Catalyzes the double cyclization reaction which converts lycopene to beta-carotene.
What are the official names of this protein?
Lycopene beta-cyclase, Lycopene cyclase.
What is the protein family that this protein belongs to?
Belongs to the lycopene cyclase family.
Protein: NAGB_STAAB
Sequence: MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLYEQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDAMLFKQYPYFNRKNIHIPNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTESTIKANSRYFENEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVDVPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: SPTC1_MACFA
Sequence: MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKIVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCRQIHKALQGISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCMDRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTAEELERAASTIKEVAQAVLL
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity).  Required for adipocyte cell viability and metabolic homeostasis (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PMP9_CHLPN
Sequence: MKSSLHWFLISSSLALPLSLNFSAFAAVVEINLGPTNSFSGPGTYTPPAQTTNADGTIYNLTGDVSITNAGSPTALTASCFKETTGNLSFQGHGYQFLLQNIDAGANCTFTNTAANKLLSFSGFSYLSLIQTTNATTGTGAIKSTGACSIQSNYSCYFGQNFSNDNGGALQGSSISLSLNPNLTFAKNKATQKGGALYSTGGITINNTLNSASFSENTAANNGGAIYTEASSFISSNKAISFINNSVTATSATGGAIYCSSTSAPKPVLTLSDNGELNFIGNTAITSGGAIYTDNLVLSSGGPTLFKNNSAIDTAAPLGGAIAIADSGSLSLSALGGDITFEGNTVVKGASSSQTTTRNSINIGNTNAKIVQLRASQGNTIYFYDPITTSITAALSDALNLNGPDLAGNPAYQGTIVFSGEKLSEAEAAEADNLKSTIQQPLTLAGGQLSLKSGVTLVAKSFSQSPGSTLLMDAGTTLETADGITINNLVLNVDSLKETKKATLKATQASQTVTLSGSLSLVDPSGNVYEDVSWNNPQVFSCLTLTADDPANIHITDLAADPLEKNPIHWGYQGNWALSWQEDTATKSKAATLTWTKTGYNPNPERRGTLVANTLWGSFVDVRSIQQLVATKVRQSQETRGIWCEGISNFFHKDSTKINKGFRHISAGYVVGATTTLASDNLITAAFCQLFGKDRDHFINKNRASAYAASLHLQHLATLSSPSLLRYLPGSESEQPVLFDAQISYIYSKNTMKTYYTQAPKGESSWYNDGCALELASSLPHTALSHEGLFHAYFPFIKVEASYIHQDSFKERNTTLVRSFDSGDLINVSVPIGITFERFSRNERASYEATVIYVADVYRKNPDCTTALLINNTSWKTTGTNLSRQAGIGRAGIFYAFSPNLEVTSNLSMEIRGSSRSYNADLGGKFQF
What are the official names of this protein?
Probable outer membrane protein pmp9, Outer membrane protein 10, Polymorphic membrane protein 9.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: XPT_LISW6
Sequence: MKLLEEFIKEKGTVLPGNVLKVDAFLNHQIDPGLMQEMGKAFAERFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFARKKKSVTLTDNLYTSTVYSYTKKESNDISVSKQFLTDADTILVIDDFLANGQAALGLLEIAELAGAKVAGIGIVIEKSFQQGRELLNKTGIPVYSLARIASLENEGILFLEEE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1847_VIBVU
Sequence: MKIWVDADACPKVIRETIVRAAERTGVECTFVANHVVPVPRRPNIHSLQVPAGFDIADNEIVKRVEPNDLVITSDIPLADEVITKGALALSSRGELYTKDTIKARLNIRDFMETMRSSGIQTGGPAALSQTERREFANHLDRILAKFKK
What are the official names of this protein?
UPF0178 protein VV1_1847.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: Y839_TREPA
Sequence: MDKKARAHTVIVCLVGALSLACAYLLGGSMKYLRGDVSRFWTSSRMQRHPAHSSQPVVRTFTDADGYTCLDQAHPHTIVIDATRVRVSVQVCAQRRSLAYKVVKNSVYDPLSIHLDPTMLVLRRGKKTVRESTPPADSPGVMQSALNVRDTLRDWFYTFWKNVWGSRWGHSVVPIEAIICVPAQHNVHNLKVRVKDSSLRLEGIEVRFADVYAHASELKLNGVRTDRTLLHTTDGDTQCSRCVLSDAHLYTDRGTLSFDGTLQGNSEIGTRTGTVVARFTERQSYYALSVFSGHGAVYINDQRVRKTLGTCLSTGGSAQLCVRNERGVLHVYFPQ
What are the official names of this protein?
Uncharacterized lipoprotein TP_0839.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ISPH_BACSU
Sequence: MDVIKISPRGYCYGVVDAMVIAKNASLDKSLPRPIYILGMIVHNKHVTDAFEEEGIFTLDGSNRLDILKQVDKGTVIFTAHGVSPEVRRIAEEKGLVAIDATCPDVTKTHNLILEMKEKGYHVIYIGKKGHPEPEGAVGVAPEIVHLVETEEDVKNLDIQSEKLIVTNQTTMSQWDVHDIMELVKEKYPHVEYHQEICLATQVRQEAVSEQAKKADLTIVVGDPKSNNSNRLAQVSEEIAGTKAYRIGDLSELKLEWLKGVNTVAVTAGASTPTPITKEVIRFLEQFDHEDPSTWTTEHNIPLKKILPKVKAKN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.