PharMolix/UniProtQA huggingface dataset:
Protein: SYI_STRP1
Sequence: MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELNAGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIEQVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFEADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGKGILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGKFGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGEDDYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINHSYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGFTHPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSSLITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVASVDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGTVDKYMTIVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRRMQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILEAWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIVSQLTIADLADAPADAVAFEGVAFIVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAKIIEENFPEAVAEGFEESGK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMIM1_DANRE
Sequence: MESNGASVQYNRWSEDNITLQEPQSRSRLLGIYNRVFTGRLVIMFKIAASLTVMVVMYIAGYITGFYVHQCG
What is the function of this protein?
Regulator of red blood cells formation.
What are the official names of this protein?
Small integral membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the SMIM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RU1C1_SORBI
Sequence: MPRYYCDYCDTYLTHDSPSVRKQHNAGYKHKANVRTYYQQFEEQQTQSLIDQRIKEHLGQAAAFQAGAPFNQHMLTFPGAVARPRLPILPTPGMPHGFPQAPGAPLMPGVRPPILPAPGIPGYPGGPPTMLQPGAPPGSMPQPGAPPGSMPQPGAPPGSMPMQMAPLPRPPTLPPPTSGVPGAPIPNSAAPPAIYQTNPPAPAGPTSGAPPAPPTAPQPAFSYAQPSEGNH
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C-1, U1 snRNP C-1, U1-C-1, U1C-1.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BL1S4_ZYGRC
Sequence: MSQESNDDSLGIDKLSVDYDYLLYKIADYVSSIEFQTNQICKRQNELITKDIVNGIVDENIKHFREILTKCEKLENYFDMLDQINMITENFKTRLAQVARDYKELQKP
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit CNL1, BLOC-1 subunit CNL1, CNO-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S4 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Punctate pattern.
Protein: TAER_MYCUA
Sequence: MSSAQREFEIVLYGATGFSGMLTGQHLAQRDTNARIALAGRSPQRLRAVRDKLGPLASDWPLVVADASQPATLEEMATRAQVILTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIVLACGFDSIPSDLNVHHLYRRAAEDGTGELAETNLVLRSFSQRWASGGSVATYSEAMRTASSDPEAYRLVNDPYTLTTDRSAEPDLGPQPDFSMRRGRDLAPELAGFWTGAFVQGPFNTRIVRRSNALQDWAYGKQFRYSETMSLGRSFAAPIASAAVTGAIAGGIGLGNKYFSRLPQRALERVTPKPGTGPSQKSRERGHYRCETYTTTTTGARYLATFAHNVDAYASTAVLLGESGLALALDRDRLSELRGVLTPAAAMGDALLARLPQTGVVVSATRLH
What is the function of this protein?
Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.
What are the official names of this protein?
Trans-acting enoyl reductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.
Protein: YMGK_ECOLI
Sequence: MFSKLAQSSIKAMF
What are the official names of this protein?
Protein YmgK.
Protein: NDK2_TOBAC
Sequence: MGCLSVVGASPCVSSSALSSPTSRLSCAPSCKLILNPIKKNHHLAAFQPAVHLFASNQSRSHASKRNHTTRIFLPHLVASMEEVEETYIMIKPDGVQRGLVGEIISRFEKKGFKLTGLKLFHCPKELAEEHYKDLQSKPFFPKLIDYITSGPVVCMAWEGVGVVASARKLIGATNPLNAEPGTIRGDLAVQTGRNVVHGSDSPDNGKREIALWFGEGELCSWTPVQEPWLIE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 2, chloroplastic, Nucleoside diphosphate kinase II, NDK II, NDP kinase II, NDPK II.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPB_BACSU
Sequence: MWLLIIACAVILVIGILEKRRHQKNIDALPVRVNINGIRGKSTVTRLTTGILIEAGYKTVGKTTGTDARMIYWDTPEEKPIKRKPQGPNIGEQKEVMRETVERGANAIVSECMAVNPDYQIIFQEELLQANIGVIVNVLEDHMDVMGPTLDEIAEAFTATIPYNGHLVITDSEYTEFFKQKAKERNTKVIIADNSKITDEYLRKFEYMVFPDNASLALGVAQALGIDEETAFKGMLNAPPDPGAMRILPLISPSEPGHFVNGFAANDASSTLNIWKRVKEIGYPTDDPIIIMNCRADRVDRTQQFANDVLPYIEASELILIGETTEPIVKAYEEGKIPADKLHDLEYKSTDEIMELLKKRMHNRVIYGVGNIHGAAEPLIEKIHEYKVKQLVS
What is the function of this protein?
Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate.  Both the 44-kDa and the 33-kDa forms are required for PGA synthesis.
What are the official names of this protein?
PGA synthase CapB, Gamma-polyglutamic acid synthase.
Protein: GATB_COXBN
Sequence: MEWEPVIGLEVHVQLRTQSKIFSGAATAYGAEPNTQACAIDLGLPGVLPVLNKEAVKLAVCFGLSVNASIPPYSIFARKNYFYPDLPKGYQISQYNFPIVQNGHLDIENEDGTTKRIGITRAHLEEDAGKSFHEGMQGYSGIDFNRAGTPLLEIVSEPDIRSAQEAVAYLKALHSLVRYIGVSDANMQEGAFRCDVNISLRPKGEEKFGTRAEIKNVNSFRFVERAILFEINRQKEILENGGTIVQETRLYDAVQDETRSMRTKEEAHDYRYFPDPDLLPVEIGPEFIEAVKNQLPELPWEKRKRFAASYQLSNYDVKLLTTQIEIANYFETVLKIDKTIPPKLAANWINGDLAAALNKNNLSITQSPINAEQLAGLLHRIADNTLSGSMGKQVFETMWGGEGDADTIIERHGLKQITDTEALEKIIDEVIENNPTQVEQYRSGKDKLIAFFVGQVMKATKGKANPQQVNELFKKKL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: EASE_EPIFI
Sequence: MRHFVTFVVGFLLSWGFLSSLQDPPSCRCRPWEPCWPDSHQWTSLNASIDGNLVHVQPVGSVCHDPHYDAVACGDVLDLSRNSGWRASNPATLQDWIWETGSGDNESCLLVSSSERPQEIPCHQGRLPLYSAAVKSTAHVQGVIRFAKDHNLRLVIKNTGHDATGRSAAPDSLQIHTYFLKDIHYDDNFLVHGDATGSGPAVTLGAGVVHSEVYKHGIDHKYSVVGGECPTVGIVGGFLQGGGVSSWSGFTRGLAVDNVLEYQVVTANAELVIANEHQNQDLFWALRGGGGGTFGVVTQATVRAFPDDPTVVSTLVLSSTRADTSFWVKAISRLLSILRSCNQQNVHGQLIITRPSVDILNAGLTLHFSNMTNVLHAETLLQPHIASLSEDQISTTLTSKFVANINSELRLDADIHPRGIGTLQTSMMISNELFGSSEGPLTVAQVFGKLPIGPNDLLFTSNLGGCIAANKGLDTAIHPAWRSSAHLVTYVRSVEPSIEAKKLALKEITNKYMPILYSMQPSFKVSYRNLGDPNEKNYQEVFWGEKVYKRLASIKAKLDPDGLFISKLGVGSEDWDTEGMCYQPQNRVSQPLRSLKYFLSVLKDT
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid ergovaline, the predominant ergopeptine product in E. festucae var.  lolii (PubMed:17308187).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (By similarity).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (By similarity).  Agroclavine dehydrogenase easG then mediates the conversion of chanoclavine-I aldehyde to agroclavine via a non-enzymatic adduct reaction: the substrate is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione (By similarity).  The presence of easA is not required to complete this reaction (By similarity).  Further conversion of agroclavine to paspalic acid is a two-step process involving oxidation of agroclavine to elymoclavine and of elymoclavine to paspalic acid, the second step being performed by the elymoclavine oxidase cloA (By similarity).  Paspalic acid is then further converted to D-lysergic acid (By similarity).  Ergovaline is assembled from D-lysergic acid and three different amino acids by the D-lysergyl-peptide-synthetase composed of a monomudular (lpsB) and a trimodular (lpsA) nonribosomal peptide synthetase subunit (PubMed:17308187, PubMed:11592979).
What are the official names of this protein?
FAD-linked oxidoreductase easE, Chanoclavine I synthase, Ergot alkaloid synthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: VPA_BOTAT
Sequence: ALVLIAFAQVLQQCP
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This protein is functionally similar to blood coagulation factor Xa (By similarity).  Potent calcium-independent prothrombin activator, possesses high hemorrhagic activity along with metalloproteinase activity.  Has considerably stronger activity than FXa.
What are the official names of this protein?
Venom prothrombin activator, vPA.
Protein: PAN_METM7
Sequence: MSYPDDYSTDIEKNKMDLKEFKEKTQIAELESKVLRLELKNKDVTRENVQIKKENEILKRELDKLRIPPLILGTILDKVNERKAVVKSSTGPNFLVNLSQFVDPEDIVPGARVCLNQQTLAIVEVLPKEKDYRAMAMEIEEKPDISFEDIGGLNNQIRDIKEVVELPLKNPELFEKVGIVPPKGVLLYGPPGTGKTLLAKAVAYETNASFVRVVGSELVKKFIGEGAKLVRDVFKLAKEKSPCIIFIDEIDAVASKRTESLTGGDREVQRTLMQLLAEMDGFDSRGDVKIIAATNRPDILDPAILRPGRFDRIIEISMPDEDGRLEILKIHTEKMNLKNVDLREVAKLAENMVGADLKAVCTEAGMFAIREEREFIKMDDFKEAISKITGKKEKCSYDMPQLTVMYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LIBAS
Sequence: MAKVVSRIVKLQIESGSAKPSPPVGPAIGQAGIPIMAFCKAFNAATEGMEKGIPIPTTVTCYKDKSFTFTMSQPPVSFFLKKEVGIKSGSKLPGKESCGSITRENIRKIAQLKMQDMGAIDIEGAMRMVEGSACSMGISVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UBIE_PARDP
Sequence: MTPDEPKETHFGFRTVAEKDKAGLVHGVFSRVASRYDVMNDLMSGGVHRIWKTAMMDWLAPRDGQHLLDVAGGTGDIAFRFLDRAPGARVTVCDMTESMLVEGRKRAEAGKQADRLAWVTGDAMALPFADDSFDRYTISFGIRNVTRIPDALAEARRVLRPGGRLMVLEFSQMPVPMLQWLYDRYSFNVIPVMGQIVANDRDSYQYLVESIRKFPDQETFATMIREAGFGRVQWRNLSMGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RH16_ARATH
Sequence: MGKTKLKPVEDVNSEVVDEVEKAEEVEEQRNDREQEEEQKEEEAPKSFEELGLDSRLIRALTKKGIEKPTLIQQSAIPYILEGKDVVARAKTGSGKTLAYLLPLLQKLFSADSVSKKKLAPSAFILVPSRELCQQVYTEVSSLIELCRVQLKAVQLTSSMSASDMRNALAGLPEILVSTPACIPKCFAAGVLEPTAVSESLSILVLDEADLLLSYGYEDNLRSVTSIIPRRCQCLLMSATTSSDVEKLKKLILHNPIVLTLTEDNDKEEAVPSNVQQFWISCSAQDKLLHILALLKLEVVQKKILIFINTIDMGFRLKLFLEKFGIKSAILNGELPQNSRLHILEQFNAGLFDYLIATDDNSQTKKQKEEAKGEANKENKKNNKRSKPKLDAEFGVVRGIDFKKVHTVINFDMPQSVTGYIHRIGRTGRAYSSGSSVSLISPDEMEGFEDIKSFLASDKNKDIDIITPFPLLTENAVESLRYRAEDVAKSVTKIAVRESRAQDLRNEIINSEKLKAHFEANPRDLDLLRHDKPLSKTAPAPHLKDIPEYLVDAKTQEASKMVKLARAAMGNTRRSGGGGGRNNKNKKRSRKGSDPLKTFNPNGSKRGAVGQKDGKDSSSTKKQKTV
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 16.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
Protein: VPK25_HUMAN
Sequence: WASQVSENRPVCKAIIQGKQFEGLVDTGADVSIIALNQWPKNWPKQKAVTGLVGVGTASEVYQSTEILHCLGPDNQESTVQPMITSIPLNLWGRDLLQQWGAEITMPAPLYSPTSQKIMTKMGYIPGKGLGKNEDGIKIPVEAKINQKREGIGYPF
What is the function of this protein?
Retroviral proteases have roles in processing of the primary translation products and the maturation of the viral particle.  Endogenous Pro proteins may have kept, lost or modified their original function during evolution.  This endogenous protein has retained most of the characteristics of retroviral proteases.
What are the official names of this protein?
Endogenous retrovirus group K member 25 Pro protein, HERV-K_11q22.1 provirus ancestral Pro protein, Protease, Proteinase, PR.
What is the protein family that this protein belongs to?
Belongs to the peptidase A2 family. HERV class-II K(HML-2) subfamily.
Protein: PLAS_MICAE
Sequence: ETFTVKMGGDAGTLQ
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface.
Protein: ETAA1_BOVIN
Sequence: MSRRRKHGDSSGLKQTPRKAMATEEGSLVFESGKRRLRAARGSGPQGPGERPPRPLPQQEQPPVAASCRKSNTEERYETPKRMLQMDLLSSTFSSPNDPDGQNDIFWDQNSPMTKQLDKGRKKQLYTTDSDEISHIVNRIAPQDEKPTTDSMLGVWIGDTAIPCTPSVAKGKSRTKLSCTKLKSQNQEEELMKLAKQFDKNMEELDVIQEQDKRNHDLIQMISEAETSLNCRDNVQMQLLCDTVPEIDKALLKKPVKENTKISVVNDQTSSQKPFDQNAEAAFIAMFDGSTQKCSGQLSQDLSDSFLKTSNTTFGKKNTLKEEKIITNESVVTENLPSKTLGSLSHQVDNPGMTKSYVTFCTKEPGTFNKHIDTFTTSDFEDDWENLLSNEPFVMQNIETSELFPAPKTIQIADQKEMCSFNSKEAKSKSGMNKSVDVKLRDSKILQGLPSNTWNNELTDAEKYRFSPKPNDKPNKLSTTGNKMKLEKSFNIVVNQDKIQDCAVASNLTKVNEDTHTKFNCKVNASEKKSALKPGCSNKSIFNQSLKVPANVKPFGSATLGSTTSVCNPDQTNGSKLGSFFDDWNDPSFTNEIVKACHQLENSWEADDVDDDILYQACDDIERLTQEQNIRVDSKTSESVLEINNSSKHGAKNVFTTPKQGSQFMQSKHLNLNSISAQTSSLANSLQINKSVKMERGEMYGNSPGFLGATTNLSIYSKNSDCQISNLHVSCNNPDVPKQVNSSKSVLTGSSSLNVGSHHMSTEIAASKNRLSTLHLSKSTTRGKAQSDLNRAVRLSEYVFTKMKNCPMLSPFNNSSVTGSISDTKIAQGLEKNKTVNPLPGKAVQQQPLVKFSEPLKQPSKEEEEKNRKCSPEEIQRKRQAALIRRMAKAQASSVKKGR
What is the function of this protein?
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity.  Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1.  Probably only regulates a subset of ATR targets.
What are the official names of this protein?
Ewing's tumor-associated antigen 1 homolog.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage following replication stress. Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex.
Protein: CX6C2_THUOB
Sequence: KMLGVVAKKPMSDYE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C-2, Cytochrome c oxidase polypeptide VIc-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DSVA_DESVH
Sequence: MAKHATPKLDQLESGPWPSFVSDIKQEAAYRAANPKGLDYQVPVDCPEDLLGVLELSYDEGETHWKHGGIVGVFGYGGGVIGRYCDQPEKFPGVAHFHTVRVAQPSGKYYSADYLRQLCDIWDLRGSGLTNMHGSTGDIVLLGTQTPQLEEIFFELTHNLNTDLGGSGSNLRTPESCLGKSRCEFACYDSQAACYELTMEYQDELHRPAFPYKFKFKFDACPNGCVASIARSDFSVIGTWKDDIKIDAEAVKAYVAGEFKPNAGAHSGRDWGKFDIEAEVVNRCPSKCMKWDGSKLSIDNKECVRCMHCINTMPRALHIGDERGASILCGAKAPILDGAQMGSLLVPFVAAEEPFDEIKEVVEKIWDWWMEEGKNRERLGETMKRLSFQKLLEVTEIAPVPQHVKEPRTNPYIFFKEEEVPGGWDRDITEYRKRHLR
What is the function of this protein?
Part of the complex that catalyzes the reduction of sulfite to sulfide.  The alpha and beta subunits may have arisen by gene duplication.  They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme.
What are the official names of this protein?
Sulfite reductase, dissimilatory-type subunit alpha, Desulfoviridin subunit alpha, Dissimilatory sulfite reductase subunit alpha, dSiR alpha, Hydrogensulfite reductase subunit alpha.
Protein: CLP1_DROER
Sequence: MSEDHGKDYTLEADSELRFEIEHKDAKVLVSLVSGFAELFGTELVKKKQYEFGVGAKVAIFTYQGCVLHVSGKMDVCYISKETPMVQYVNCHTALEQFRMEAEEKDRHGPVAMVVGPMDVGKSTLCRILLNYAVRVGRRPLYADLDVGQGSIAISGNVATILIERPANVEEGFSKTAPLVYHFGHKSPGANSILYNAVVSKMAEVTLHSLNSNKRTKSSGIIINTCGWVKGSGYAHLLHAAKAYGACAIFVLDQERLYNELLRDVPKGVHVVLLPKSGGVVERSKEQRHEARDQRVKEYFYGNARAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPLGMKAEDNKTKVVAVTPTPALIHHVLALSFSESVEDDVIGTNVAGFCCVTEVDMERQAVMLLSPQPRPLPPNALLLWSELQFMDNHT
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
Protein CLP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSB2_PSEPU
Sequence: MARGVNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDKQTGQKVERTEWHRVSLFGKVAEIAGEYLRKGSQCYIEGKLQTREWEKDGIKRYTTEIIVDMQGTMQLLGGRPQNQQQGGDPYNQGGSNQQPRQQAPRQQRPQQPPAPQQPAQPAADFDSFDDDIPFMDPYRFNWHLQ
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: VG11_GAHVM
Sequence: MTSERALTLAPGKVSTADIYEADFSFRREFVRQILQREFILFEISMYIIFIVTFCYKIILFLFRIIPKDLDHRQRNRGRKMSASA
What are the official names of this protein?
Uncharacterized gene 11 protein.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RL16_CAMFF
Sequence: MLLPKRTKYRKMMKGRNRGYATRGVDLALGEFGLKAVEAGRVNSRQIESARQAYTRHVKRQAKTWIRVFPDKPITKKPLETRMGKGKGGVEEWVMNIKPGRIIFEMSGVSEELAREALTLAMHKLPFKTKFVTKESENEVY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CLPP_BURMS
Sequence: MINRAQLLDTLASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLRDRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_SHIB3
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGT_ORYSI
Sequence: MPSSGDAAGRRPHVVLIPSAGMGHLVPFGRLAVALSSGHGCDVSLVTVLPTVSTAESKHLDALFDAFPAVRRLDFELAPFDASEFPGADPFFLRFEAMRRSAPLLGPLLTGAGASALATDIALTSVVIPVAKEQGLPCHILFTASAAMLSLCAYFPTYLDANAGGGGGVGDVDIPGVYRIPKASIPQALHDPNHLFTRQFVANGRSLTSAAGILVNTFDALEPEAVAALQQGKVASGFPPVFAVGPLLPASNQAKDPQANYMEWLDAQPARSVVYVSFGSRKAISREQLRELAAGLEGSGHRFLWVVKSTVVDRDDAAELGELLDEGFLERVEKRGLVTKAWVDQEEVLKHESVALFVSHCGWNSVTEAAASGVPVLALPRFGDQRVNSGVVARAGLGVWADTWSWEGEAGVIGAEEISEKVKAAMADEALRMKAASLAEAAAKAVAGGGSSHRCLAEFARLCQGGTCRTN
What is the function of this protein?
UDP-glucose-dependent glucosyltransferase catalyzing the c-glucosylation of 2-hydroxyflavanones.  Acts preferentially on the dibenzoylmethane tautomers formed in equilibrium with 2-hydroxyflavanones.  No activity with naringenin or naringenin chalcone.
What are the official names of this protein?
UDP-glycosyltransferase CGT, UDP-glucose:2-hydroxyflavanone C-glucosyltransferase, OsCGT.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.