PharMolix/UniProtQA huggingface dataset:
Protein: DPH2_YEAST
Sequence: MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLISAYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTAYSACCVDEVAAEHVHAEVVVHFGDACLNAIQNLPVVYSFGTPFLDLALVVENFQRAFPDLSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFHVPEDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDPALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKKHYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEEVTWTGKWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTHLELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGADIEEGISGVARGYGFDREDAMKKENK
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:8406038, PubMed:24422557, PubMed:27694803, PubMed:31463593, PubMed:32576952, PubMed:34154323).  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1 (PubMed:8406038, PubMed:24422557, PubMed:27694803, PubMed:31463593, PubMed:34154323).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (PubMed:31463593).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_DESVH
Sequence: MQFTGAFTAIVTPFRNGRVDEERFRELIEWQIEQGINGLVPCGTTGESATLSHDEHRDVIRICVEQVKGRIPVLAGAGSNNTREAIDLTRFAKEAGADGALLITPYYNKPTQEGLYLHFKAIASEVSMPFIVYNVPSRTGTNICPETLARLNRDIPEVVGVKEATGNLIQVSEILEYCGTDFQVLSGDDFTVLPLLSVGGCGVISVTSNVVPAKMSDMCRAFKAGDLATARRLHFELSPINRAMFLETNPIPVKTALALMGRIDLEMRLPLCPLQQVNQSRLRDILAAAGIL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_LIMRJ
Sequence: MKRALVSVSDKQNLVPFVKGLVENGFEIISTGGTKRVLDEAGIETIGIEDVTHFPEILDGRVKTLNPYVHGGLLARRNLPEHMATLEKLNITPIDLVCVNLYPFKETIEKPGVEIADAIENIDIGGPSMVRSAAKNYHDVTIVVDQADYDEVLAQIKEDGETSLATRARLAAKAFRHTAAYDSLISQYLTKQTGLEDPEKLTLSWDLKETMRYGENSHQKAWLYEDALPKAFSVLQAKQLHGKKLSYNNIKDADEALRCIREFDEPTVVAMKHMNPCGIGRGDSLVQAWDRAYEADPVSIFGGVIALNRQVDLVTAEKMHKIFLEIVIAPGFDDDAFELLAKKKNIRLLTLDFSKKDEPTKHEVVSVMGGMLLQEQDMLKEDYHDWQCVTEKQPTEEQLKTLMFAWKAVKHAKSNAIVLANDERTLGVGEGQPNRIDSLKIAVKHAGEAIDDRTVMASDAFFPFGDCVEYAGQNGIKAIVQPGGSVRDQESIEMANKYGIAMVTTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MRGA8_MOUSE
Sequence: MDKTILGSIDIETLIRHLMIIIFGLVGLTGNAIVFWLLGFHLHRNAFLVYILNLALADFFYLLCHIINSIMFLLKVPSPNIILDHCFYTIMIVLYITGLSMLSAISTERCLSVLCPIWYRCHRPEHTSTAMCAVIWVMSLLISILNGYFCNFSSPKYVNNSVCQASDIFIRTYPIFLFVLLCLSTLALLARLFSGAGKRKFTRLFVTIMLAILVFLLCGLPLGFFWFLSPWIEDRFIVLDYRLFFASVVLTVVNSCANPIIYFFVGSFRHRLKQQTLKMFLQRALQDTPETPENMVEMSRSKAEP
What is the function of this protein?
Orphan receptor.  May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo.  May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
What are the official names of this protein?
Mas-related G-protein coupled receptor member A8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS5_XANCB
Sequence: MAEERAPRGRDRDRNREEKVDDGMIEKLVAVNRVSKTVKGGRQFTFTALTVVGDGLGKVGFGYGKAREVPVAIQKSMEQARKNLATVDLNNGTLWHAVKSGHGAARVYMQPASEGTGVIAGGAMRAVLEAVGVKNVLAKAVGSRNPINLVRATLKGLSEVQSPARVAAKRGKKVEELNHG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ALF1_XYLFA
Sequence: MSIEQLAETAQAMVASGKGIIAIDESAGTIAKRFSSVGIENIEENRRAYRELLLTTPKLSDYISGAILFDETIRQSTKAGVPFPKYMADHGIIPGIKVDKGAYPLAGCPGELVTEGLDGLRARLEEYYKLGARFAKWRAVINIGDDIPSGMCIDANVHALARYAALCQEQGLVPMVEPEVIMDGNHDISAAYEVTEATLRSLFNALYEQNVVLEGTILKASMVIPGTDCEEQASIDEVAESTVMCLKSTVPAILPGIVFLSGGQTDAQSTAHLNAMNQLDPLPWPLSFSYGRAMQQAALKLWSQDMKGNFAKAQQVVYERAKENGLAALGKWKG
What are the official names of this protein?
Probable fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: KGUA_NEOSM
Sequence: MRKGILFIISSPSGGGKTTVADFLVGQDLSIKRSISFTTRQPRGEEKDGIDYYFVSKDEFNRLLQEGEMLEHATVLQNQYGTSHRYIEETLALGIDVLCCIDWQGAEQIRKKTNCISIFLLPPSLQKLKTRLTSRGTDTADVIEYRLKVALEEIQHFSKYDYVLVNDDLTETKQKVLSIITAEREKLVQNHRVVECFVASLLEQTI
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_RHIWR
Sequence: MTRSFLDLADAGAAGVRLMLDEAVSRKKARAGLPKGAPDRDAPLAGHTLAMIFEKNSTRTRVSFDMAMRQLGGTTIVMDAGSMQLGRGETIADTARVLSRYVDAIMIRTDDHRKAVDLARYADVPVINGLTDRSHPCQIMADLQTILEHKGRVEGLGWAWLGDGNNVLHSIVEAGSLLGFPVRIGCPEGYDPDAEVLAEARARGGDILLSRDPAEVVRGADVVVTDTWISMGQAHAEEKLAAMMPFQVDEARMAQAAPDAAFLHCLPAHRGEEVVDAVIDGPHSLIWDEAENRLHAQKAVLLWCLGRLG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_ACTP7
Sequence: MASQFELSVVSAEKEIFNGNVVSVRVTGIDGELGVYAGHTPLLTSIKPGMVKYTLEDGKEEFIYVSGGFLEVQPTIVTVLADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UNG_SHISS
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_METTH
Sequence: MVELEDLPNVGAKTAQKLRDAGFGDMMRLATATAKELSVKAEIGEGVAEKVIEAARRAEKIDFETAFDVMERRKDVGRITTGSKALDELIGGGIETQAITEVFGEFGSGKSQLSHELAVTVQLPEERGGLDAEAVFIDTENTFRPERIEQIANAFELDLEEVLNKIHIARAFNSSHQILMAEKVNELIQEGKNIRLVIVDSLTAHFRAEYVGREALATRQQKLNQHLHTLQNIANTYNAAVFVTNQVQARPDAFFGSPTKAIGGHVLGHAATYRIWLKKGLAGKRIARLVDSPHLPEGECVFKITTAGIVD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: Y5090_PSEAB
Sequence: MTQPTCPCGSGDPLDDCCGRYHQGHPAPTAEALMRSRYSAYALGLVDYLRDTTLPAQQAGLDLDGIRAWSHGSTWLGLEVENHEVLGGQPEHARVTFVARWHDAEGEHAHRECSGFVQRNGRWYFLDPTVALKLGRNDPCPCGAGGKLKKCCGPWIT
What are the official names of this protein?
UPF0225 protein PA14_50900.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: B2_BBV
Sequence: MPSKLALIQELPDRIQTAVEAAMGMSYQDAPNNVRRDLDNLHACLNKAKLTVSRMVTSLLEKPSVVAYLEGKAPEEAKPTLEERLRKLELSHSLPTTGSDPPPAKL
What is the function of this protein?
Binds double-strand RNA (dsRNA) with high affinity.  Suppresses the host RNA silencing-based antiviral response (By similarity).
What are the official names of this protein?
Protein B2.
What is the protein family that this protein belongs to?
Belongs to the nodaviridae B2 protein family.
Protein: IDI_SERP5
Sequence: MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLWTNSCCGHPRWGESTLAAAQRRLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGLFDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLTIMKDLGANEMERWARLAAS
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_HAEIN
Sequence: MVTIRLSRGGAKKRPFYQIVVADSRSPRDGRFIERVGFFNPIAQGNAERLRINLERVNHWVAQGASLSDRVASLVKEAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y516_SYNY3
Sequence: MNNKKLSLTLPLVGILALTACNQPKEEIDPLSQLREKGECLDCNLAGADLREFNLENARLNRSDLSGANLSGVNLRRALLDRANLTGANLSETDLTEAALTEANLAGADLSGANLERSFLRDVDLTGANLKGANLAWANLTAANLTDVDLEEAEFWETTMPDGSRR
What are the official names of this protein?
Uncharacterized protein slr0516.
Protein: CTU1_YEAS7
Sequence: MSFTAPSDPVNKPTKVKVSQLCELCHSRKALIRRPKNLSKLCKQCFCLVFETEIHNTIVANNLFQRGEKVAVGASGGKDSTVLAHMLKLLNDRYDYGIEIVLLSIDEGIIGYRDDSLATVKRNQQQYGLPLEIFSFKDLYDWTMDEIVSVAGIRNSCTYCGVFRRQSLDRGAAKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITQSSGSPIKRSKPFKYSYQKEIVLYAHYMKLDYFSTECTYAPEAFRGTAREYMKNLEAVRPSCIIDIIQSGENLALKAKKSNARKRVVKFVDGNRCARCGYLSSNNICKACMLLEGLEKSRAQVAIENDTSADGAALKLRALEKLSF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1, Needs CLA4 to survive protein 6, Thiolation of uridine in cytoplasmic tRNA protein 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: SSRP_AERHH
Sequence: MSKKNSKNKAGSNTIALNRSARHEYFIEEKIEAGLSLQGWEVKSLRAGKANISEAYVIFRDGEAYLFGSSFLPLQAASSHVVCDPTRTRKLLLSRRELDKLESLIARQGYTVVPLALYWKQCWVKVEIGLVKGKKEHDKREDTKAREWDREKARIMKNKHRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DPOG1_XENLA
Sequence: MNRLLQKGTSLVPSWRTRGCRYRRCSYAPQLHAKPLEMETSQRRMNPLNIQMLSKGFHEQIFRGKQVQHAEEDVQRSITHLKNHELWGQETSTVPDVELQLPKMYGNNIEEHFQILAQKQSLPYLEAANDLLNCQLPAMPQTWAWQSGWTRYTATGEKELVDFPDEKAMVFDVEVCVTEGCCPTLAVAASPQNWYSWCSRRLIEGRYTWSKELLLSDLFPLETSMNCNYMTKNNWTERLVVGHNVSFDRAHIKEQYLIKGSKTRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSNFSGSPISSWDWVNISSINNLADVHALYVGGPPLEKEARELFVKGSMSDIRTEFQELMRYCALDVQATHEVFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMKLANDACQLLTKDAYKEDPWLWDLEWDIQESKQKKTKISKKQKKANEAAESVGNKLVEDHNEDPGPPTEKEESRPSMGKLYLEDLKLKTLPLLPKRNQHLPGHPGWYRKLCPKLEDPDWLPGPGLISLQMRLTPKLMRLTWDGYPLHYSEKHGWGYLVPGRKNNKLNNEEEEEIIPCPYRAIEDIYAEYSKNKTKDGCLSQHSTIPEEFMLTDDNSMWQKVEELSRTEMDLSSEVPATAKAKKRNNSSEHPVKLEMEFDSLPDNHHGNSPCGDVNVSGCWFYKLPHKDGNANNVGSPFAKDFLPKMEDGTLQASTGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKNELHRTITRDPEFDEENKYGAILAQVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHLIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSSGTDLHSKTASTVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGISVERGEENSVNLQDLRKIQKDATKRSRRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCRISRALEPTAVKGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVHSKDRYRAALALQITNLLTRCMFASRLGIQDVPQSVAFFSAVDIDKCLRKEVTMDCSTPSNPNGMEKRYGIPQGEALDIYQILKVTKGVL
What is the function of this protein?
Involved in the replication of mitochondrial DNA.  Associates with mitochondrial DNA (By similarity).
What are the official names of this protein?
DNA polymerase subunit gamma-1, Mitochondrial DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: US8A_HHV11
Sequence: MDPALRSYHQRLRLYTPVAMGINLAASSQPLDPEGPIAVTPRPPIRPSSGKAPHPEAPRRSPNWATAGEVDVGDELIAISDERGPPRHDRPPLATSTAPSPHPRPPGYTAVVSPMALQAVDAPSLFVAWLAARWLRGASGLGAVLCGIAWYVTSIARGA
What are the official names of this protein?
Protein US8.5.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 US8.5 protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: YS025_HUMAN
Sequence: METANGEEPPAGPPVSLHGRRLLRVGGACPTPLPVLQRLPPSALHHTLHCVPRRVCVSPLGQVTRIPPVRTVRRAPSGLLPQRRGGPSWWPPSGVARGGPSWWPPSGVVRGGPSSWPPSGVAEPREALGLP
What are the official names of this protein?
Putative uncharacterized protein FLJ45684.
Protein: NIFW_FRASE
Sequence: MSALTRQLEEFRRCSTAEQYFELLDVDYDPRVVAVNRLHILRYFAEEIAGLHEGADAEVSPEVLLRDYRAALIRAYEAFTTATGLDHRLFKVLKDRAPEPAGFVATTDITVERPATAQSDEKGQDR
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: RNPA_VIBVU
Sequence: MNTYAFNRELRLLTPEHYQNVFQQAHRAGSPHFTIIARNNNLSHPRLGLAVPKKQIKTAVGRNRFKRLARESFRNTQHQLPNKDFVVIAKKSAQDLSNEELFKLFDKLWHRLSRPSRG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: DNAK_BIFA0
Sequence: MGRAVGIDLGTTNSCIATLEGGEPTVIVNAEGARTTPSVVAFSKSGEILVGEVAKRQAVTNVDRTISSVKRHMGTDWTVDIDGKEWTPQEISAQILMKLKRDAEAYLGEPVTDAVITCPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAALAYGLEKSKEDERILVFDLGGGTFDVSLLEIGKDDDGFSTIQVQATSGDNHLGGDDWDQRIIDWLVGEVKNKYGVDLSKDKIALQRLKEAAEQAKKELSSSMSTTINMQYLAMTPDGTPVHLDETLTRAHFEEMTKDLLDRCRTPFNNVLADAGISVSQIDHVILVGGSTRMPAVKELVKELDGGKEANQSVNPDEVVAIGAAVQSGVIKGDRKDVLLIDVTPLSLGIETKGGIMTKLIERNTAIPAKRSEIFSTAEDNQPSVLIQVYQGEREFARDNKPLGTFELTGIAPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSALPKEEIDQMIKDAEAHEADDKKRKEDAETRNNAENFAYQTEKLVNDNKDKLSDDVAKSVTDAINELKDALKGDDIEKIKAAQEKLMTEAQKIGQALYAQQGAEGAAGAADSGSANNGGDDDVVDAEVVDDDDKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MANA_BIFAA
Sequence: MKTTVTKLLATVAAASTIFGMSTLPAFAAEGKSASNGNSVNISDVNATAETRALFDKLKNSGKGDLRFGQQHATDENISSSASQGDVYETTGKYPAVFGWDAGLALRGAEKPGSGADKNANAKALAQNITDADSKGAIVTLSAHWCNPGTGKDFNDTTAVASELLPGGKYSGTFNKELDAIAATAQRAKRSDGTLIPIIFRPLHENNGSWFWWGATHASASEYKELYRYIVDYLRDVKDVHNLLYAYSPGGVFNGDSTDYLATYPGDQWVDVLGYDEYDSDDSADDSSAWINTVVKDMKMVSDQASQRGKIVALTEFGRSGDRKFKESGTGDKDTKFFSELAEALAENVPSTAYMMTWANFGGGGDNFQAYTSWKGSDGEADFKAFADSNKNLMASKDNVDYSNAPAAAMQNGSARIVTPVDGNRVTDTKVVVRVKTEGVKYSDLDLNSAIVTTDRGQNVKLKYSCNGYFTGILDLNAAGINLDQSKLTLTPQVKTKDGKTLAAADGNGSVTVKLGAKPEQTVDNVEDFDSYDNEAELQSVYSPSHSTKSNLTLVDSPEDNGTKAGNIHYDFVSYPEYNGFQRSHTPKQDWSGFSKLNMFLKADGSDHKFVVQVNAGGVTFEAYPKIDGTDGHVVSLNFGDADGNGGDFAPASWDTAHAGMKLSQKLLSKVGSFALYINDNGGNRPKSGDLTLDSIKLDGKRDAYAPNTNPTPGNTAKAQSVDDFSGYSDDAAAQSAWGNRGHTEVLSLDEGPTDGSKALRFKYDFSNGGWYDVAKYLDGANWSGESVLAFQVKGDGSGNAIGLQIGTSDGKYFLASVKLDFTGWKQIEIPLVDNANLTQSWPEDANKDNPMTEDDLASIKELVFASQQWNSESDGLDSSIADIKVEPAENTSNEQTPKDESKTEVKADKEQEQSEDTSADVTAQDPATCPISDEDSKGSTGNTTVTVKPTPDTKEPADNTGKDGLSRTGSNIISAIAAVAVLLLGGCAVLIARKRKGGDIE
What is the function of this protein?
Beta-mannanase likely involved in the utilization of carbohydrates in the human gut.  Catalyzes the hydrolysis of different beta-1,4-linked mannans, such as ivory nut mannan, konjac glucomannan, as well as carob and guar gum galactomannans, to a mixture of oligosaccharides.  The dominant product from ivory nut mannan is found to be mannotriose; mannobiose and mannotetraose are produced to a lesser extent.  Does not hydrolyze mannobiose, and hydrolyzes mannotriose at a significantly lower rate than the longer oligosaccharides.
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase, Beta-mannanase, Mannanase 26A, Man26A, Mannanase A, ManA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 26 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor. Note=Is likely to be cell attached, either by the sortase mechanism (LPXTG motif) or via a C-terminal transmembrane helix.
Protein: COAD_METTH
Sequence: MKRKYSLVAVGGTFDRFHKGHRRLLDEAFRVGETVMIGVTSDEFAAAKGEGIEPCSVRMKNLEEYLRDKDADYHVMRLDDPYGTTVTDEAFEAIVVSRETEPVAREINAIRRNRGFRELDIITIDMVNADDGIPISSTRIRRGEIDPMGHIIKRIRGALRRRRE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB1_SALTY
Sequence: MASRGVNKVILVGNLGQDPEVRYMPSGGAVANLTLATSESWRDKQTGEMKEQTEWHRVVMFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDQSGQERYTTEINVPQIGGVMQMLGGRQGGGAPAGGQQQGGWGQPQQPQQPQGGNQFSGGAQSRPQQSAPAPSNEPPMDFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: HIS6_GEOKA
Sequence: MITKRIIPCLDVKDGRVVKGVQFVQLRDAGDPVELAKAYDEQGADELVFLDISASHEGRKTMVDVVERVAAQLAIPFTVGGGIHSLEDMKRMLRAGADKVSLNTAAVLHPTLITEGADFFGSQCIVVAIDAKYDETLGSWRVYTHGGRNATNWEVVAWAQEAVRLGAGEILLTSMDADGGKNGFDIELTRRVSEAVPVPVIASGGAGKAEHFLEAFEKGKADAALAASIFHYKETSVGQVKAYLKEKGVNVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y108_NPVOP
Sequence: MATPSHVVSRLTGGRAGNPIVEVIRSNATPTDGDQLEQFVARNRSLIKEFVLVLCGFLVVIMIILFFTLLVAVLTNAYAVQVGRAQFERALQRNYAPPTDASARASTA
What are the official names of this protein?
Uncharacterized 11.7 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae 11 kDa protein family.
Protein: BBC3_MOUSE
Sequence: MARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCSLCEPGLPAAPAAPALLPAAYLCAPTAPPAVTAALGGPRWPGGHRSRPRGPRPDGPQPSLSPAQQHLESPVPSAPEALAGGPTQAAPGVRVEEEEWAREIGAQLRRMADDLNAQYERRRQEEQHRHRPSPWRVMYNLFMGLLPLPRDPGAPEMEPN
What is the function of this protein?
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (By similarity).  Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis (By similarity).  Regulates ER stress-induced neuronal apoptosis (PubMed:21159964, PubMed:22761832).
What are the official names of this protein?
Bcl-2-binding component 3, p53 up-regulated modulator of apoptosis.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Protein: RS17_ROSCS
Sequence: MTEGRRRQFKVGRVVSNKMQKTVVVAVDYLKPHPLYRKIVRRTSKFHAHDEQQCQIGDVVRIGETRPLSKTKRWEVVEIIKRNEEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.