PharMolix/UniProtQA huggingface dataset:
Protein: VP26A_MOUSE
Sequence: MSFLGGFFGPICEIDVALNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQASAEQPEM
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.  The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins.  The CSC complex seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (By similarity).  Required for retrograde transport of lysosomal enzyme receptor IGF2R (PubMed:15078902).  Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).  Required for the endosomal localization of WASHC2 (indicative for the WASH complex).  Required for the endosomal localization of TBC1D5.  Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP (By similarity).  Involved in retromer-independent lysosomal sorting of F2R.  Involved in recycling of ADRB2 (By similarity).  Acts redundantly with VSP26B in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1.  Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins (PubMed:25136126).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26A, H<beta>58 protein, H beta 58, Vesicle protein sorting 26A, mVPS26.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome. Note=Predominantly found in early not late endosomes.
Protein: ATP6_CANAL
Sequence: MFYSPLDQFEIKPLLMVNNILTLALTNYTLYLIIVVSIIFGYTSIISNGRLGSTRWGVAIIAIYDTILNLVYSQIGKAGGHFFPLIFTIFNLIFAANLISMIPYSFAISAQLVAIVSFSLALWIGNVILGLYLHGWGFFALFVPSGTPLPLVPILVLIEALSYSSRAISLGLRLGANILSGHLLMLILGSLIVNLMSSSILGFIGGIVPIVAVIAITILEVGIAIIQAYVFSILLSGYIKDSVSLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a, ATP synthase subunit 6, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYY_LEUCK
Sequence: MNFIEDLKWRGALNQITDEAGLLEAMASGKVGAYVGTDPTADSLHLGHLIPFMVLKRFQKAGGKAVIIIGGATGAIGDPRPTTERQLLSSEQLAENEKGITAQVTKLFGDNDTRIVNNNDWLGQLTLTDFLRDYGKLFSINVMLKKDVVASRLETGISFTEFTYQVLQGIDFHELWRREDVKLQIGGSDQWGNITSGIDLIHSLEGNEAKAFGLTIPLMTDSTGKKFGKSEGNAIWLDPKKTSPYTFYQFWLNQGDADVVKYLKYFTFLGSEEIDDLAEAVATNPGERLAQRRLAQEVTKFVHGESAVKEAEDLSTALFSGNVATLSAAQIADAFGGVPSFEAANTVKNIVDFLVDGGVEASKRQAREDVANGAISINGEKVTDVAAEINPLSHYDGQFVLVRRGKKKYFLGKIK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_EUNMU
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLACSTLQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWLMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTMLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGNTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHVILLHEEGSSNPLGTNPDIDKIPFHPYHTYKDLLMLTIMTILLLLIVSFSPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALTMSIIILMTVPFTHTSKMRSMMFRPFMQMTFWMFAATFLVITWTATKPVEQPFTLIGQMASMLYFLFFISNPIMGWLENKIMKT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TEX19_HUMAN
Sequence: MCPPVSMRYEEEGMSYLYASWMYQLQHGDQLSICFTCFKAAFLDFKDLLESEDWEEDNWDPELMEHTEAESEQEGSSGMELSWGQSPGQPVQGGSEAWGPGTLAAAPEGLEDAGLDPHFVPTELWPQEAVPLGLGLEDADWTQGLPWRFEELLTCSHWPSFFPS
What is the function of this protein?
Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization.  Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins.  Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.  Also during spermatogenesis, promotes, with UBR2, SPO11-dependent recombination foci to accumulate and drive robust homologous chromosome synapsis (By similarity).  Interacts with LINE-1 retrotransposon encoded LIRE1, stimulates LIRE1 polyubiquitination, mediated by UBR2, and degradation, inhibiting LINE-1 retrotransposon mobilization (PubMed:28806172).
What are the official names of this protein?
Testis-expressed protein 19.
What are the subcellular locations of this protein?
Cytoplasm. Note=Was initially reported to localize in the nucleus. However, it was later shown to localize in cytoplasm only. Cytoplasmic localization is distinct from the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: YF7A_PSEAE
Sequence: MQCRAGCGACCIAPSISSPLPGMPAGKPAGVRCLHLDENHLCGLFGRPERPAVCGQFGADPEICGDSREQALALIAEWEVITAA
What are the official names of this protein?
UPF0153 protein PA1578.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0153 family.
Protein: IHFA_RHOP2
Sequence: MTGTGRTVTRVDLCEAVYQKVGLSRTESSAFVELVLKEITDCLEKGETVKLSSFGSFLVRQKGQRIGRNPKTGTEVPISPRRVMVFKPSAILKQRINANGTASSMSSSANAAAGDKSESASGT
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CPXT2_TRIEI
Sequence: MTHSTDITTLARWFAADFSNQQQAFDNPPLFAHIRVCMRPLPYQLLNGLSLYLEQAYDITLNQPYRVRVLKLVPSENHIEIENYIIDQEAEFYGASRDPQRLKNLKTEYIKKLPGCTFITKWTGKSFKGEVEPGKGCTVVREGKSTYLKSYFEINEHKFISHDTGYDPETDQQVWGAIAGPFEFVRWASFADEVI
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcT/CpeT 2.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
Protein: ATP23_PICGU
Sequence: MDVIYRSGTKLIWSSSMNDDRQTSSEDKLKGFEWWRRSLQYRTGLGLDEEEKLQFEHDYRVKNLPQKCDSCIEYRDWMFKYSPSVKFMMEHVQKLGGNLSSKNITCDMCDGMKGGGFHPEMGILLCSNWIKDKWQLEDILTHELVHAYDHLKFKVDLTNLKHHACTEIRASALSGECRILNEIKKTGLGDFGSKFQACVRRRAAISVSANPNCSSKEEAESVVNAVWESCFNDTRPFERVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: RECA_NEIGO
Sequence: MSDDKSKALAAALAQIEKSFGKGAIMKMDGSQQEENLEVISTGSLGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAVAQCQKNGGVCAFVDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRLDIRRTGSIKKGEEVLGNETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKNDIINKSGAWYSYNGAKIGQGKDNVRVWLKENPEISDEIDAKIRALNGVEMHITEGTQDETDGERPEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHCOA_SYNAS
Sequence: MYINTETEDLKTAIDAIRKAVKDRIAPLAAEVDDSGVIKPEIYDLLWDLGLMTVTYPPEYGGSETNPGTLLCIGCEEIAKACASTALLLIIQAVGSFPLMHGGRKELLDRIAPRIVNNRELAGYLVSEPGAGSDVKAIRTKAVKDGNDWVINGTKCWATNGPIASFYSCLCRTKDDKGVQGYSFFLVERNTPGLSVGKIEHKMGMRGSQTSEVILEDVRVPAENLLGELNNGFKLAMKDFDMSRPAIAAQALGISEGAFAQMETYSRERYTFGKPLCEHGMITQIIADSAALIEAGRGLIYQAADLYDKGKKNTKLASMAKFFMGDAAVKITTDAIQVFGGYGYTHDYPVERMFRDAKLTQIFEGANQIQRIVVAREIRDEQSK
What is the function of this protein?
Mediates the conversion of cyclohexane-1-carbonyl-CoA into cyclohex-1-ene-1-carbonyl-CoA in biosynthesis of cyclohexane-1-carboxylate, a by-product produced during fermentation of benzoate and crotonate to acetate.
What are the official names of this protein?
Cyclohexane-1-carbonyl-CoA dehydrogenase, ChCoA.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RSMA_BDEBA
Sequence: MSYSRERLQRAQEAMGIAAKKSLGQNFLVSDTVINRIIDQVKAFAPEELVEVGPGPGALTDLLLELNLPLQLIELDSAIAAYWREKGLTVIEQDALRLDWKQFYTGKRVVFVSNLPYQISSSIVIERSLENEGVAAMVLMFQKEVAQKIRGTVDSDLYGLLSVYAQAFWKIETVTDAGPRDFQPPPKVASRVLSFERIESEVKNRKAFLTFVKCAFAQRRKLLKKNLSGLLSQKKLTEEQMVGWLAELGFKETARAEELSPKQFVALYKHFGFE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF13_CUPMC
Sequence: MAKEELVEFGGKVSEVLPDNRFRVILENGFEVWAYSSGRLKKNRIRVLAGDRVTLEMSPYDLTKGRINYRHKS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 3.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFP1_YEAST
Sequence: MDFTTMTMASNMATSTTTTATSAHASINSSSNFNIDIDSNQNTPSILINNNSDSSNGKNTDFNGVNNIHQKNIMNNTNNVHLYSPNIMDQTLLTPQDIAKLRRESIAHSQGMGGVSWGSISVGSWLRDEIISRRNSIVPASANGAASAAASATTTATNTLQIQQPTKRPSVSNPPYHRGYSISPQIAYTAYLPNLEKQYCKDYSCCGLSLPGLHDLLRHYEEAHISTSPNTTNMSQIPMNSAGNTSSSVRMTNNTSSANYNLQNNMAANTKNAGHKTNTMQAHSSNATNNTSINNMHANLQSNMDSNSTIRQSQHPHHQQNIIQQQLQSNSVNHTSGAVPTPSVMGSATASSTTANPNVISITGAPNSGLSMANHSQQLHLNGNLVDAVSTNDVFLRTSNSPSRHVPHNKQINSNNNSGININNNTSHNSNINMGSKNAMVNRPHTFNNYSLNKTSRNPIQHQSRKIDPHQTDLSPLVLVQDIDLSFMDDDILGPSNHNSMNSVVNPTTGSHNYNTFHSSVHAKSSQNMVEDQDIDDIDDDDDVDDDDDDDDDDDTENGSSSNGKSVHNNNYKMPQQAYIDDPARRLYVMDHEEQKPFKCPVIGCEKTYKNQNGLKYHRLHGHQNQKLHENPDGTFSVIDPDSTDSFGDGMGSAKDKPYRCEVCGKRYKNLNGLKYHRGHSTH
What is the function of this protein?
Transcription factor that regulates ribosomal protein (RP) and ribosome biogenesis (Ribi) gene expression in response to nutrients and stress.  Promotes RP gene expression under optimal growth conditions.  Leaves the nucleus upon environmental challenges, resulting in a down-regulation of RP gene transcription.  The effect of the environmental cues on SFP1 localization is mediated through the TOR pathway.  Also regulates the expression of genes involved in the G2/M transition during the mitotic cell cycle and the DNA-damage response.  Required for carbon-source modulation of cell size.
What are the official names of this protein?
Transcription factor SFP1, Split finger protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear under optimal growth conditions. Leaves the nucleus in response to stress or changes in nutrient availability. The [ISP+] aggregates appear to be nuclear.
Protein: MIH_PENVA
Sequence: LEKLLSSSSSSSGSSSPLDALGGDHSVNKRDTFDHSCKGIYDRELFRKLDRVCEDCYNVFREPKVATECKSNCFVNKRFNVCVADLRHDVSRFLKMANSALS
What is the function of this protein?
Inhibits Y-organs where molting hormone (ecdysteroid) is secreted.  A molting cycle is initiated when MIH secretion diminishes or stops (By similarity).
What are the official names of this protein?
Molt-inhibiting hormone-like, MIH-like.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: VPR_HV19N
Sequence: MEQAPEDQGPQREPYNEWTLELLEELKNEAVRHFPRPWLHGLGQYIYNTYGDTWEGVEAIIRILQQLLFIHFRIGCQHSRIGITPQRRVRDGPGRP
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: NPY2R_HUMAN
Sequence: MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.  The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
What are the official names of this protein?
Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2216_MYCTO
Sequence: MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG
What are the official names of this protein?
Epimerase family protein MT2273.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: HUTU_SALG2
Sequence: MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLAPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGCQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPSGWRWEEYQKNAQSDPHGTMQAAKRSMAAHVRAMLAFSKMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_ACTP2
Sequence: MSNIIKQIEQEQLKQNVPSFRPGDTLEVKVWVVEGSKRRLQAFEGVVIAIRNRGLHSAFTLRKVSNGVGVERVFQTHSPVVDSISVKRKGAVRKAKLYYLRERSGKSARIKERLGE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ISPH_SYNC1
Sequence: MKIILADSAGFCFGVKRATNLAFDAAEQFEHICSLGPIIHSPQVVKKLEEKGIKVIRKVEDIDHGAVIIRSHGITAEELDIIHDRELKIVDATCPFVKKAQDYATMLCNEGYSVVLVGEKDHPEVQGIISYTRGGEVFVVADCKEAQRLPNRPKLGIVAQTTQSFKNLQQIADICLGKSKEVRIFNTICDATSVRQNEARKIACEADLMLVVGGFNSANTTRLAQICQEIQPRTFHVETVEQIQDGWFEGVECVGITAGASTPRWIIDQVVERVSDMSK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PRS8A_ARATH
Sequence: MAAVGVDSRRPETAMEETCNVKGAAAKQGEGLKQYYLQHIHELQRQLRQKTNNLNRLEAQRNELNSRVRMLREELQLLQEPGSYVGEVVKVMGKNKVLVKVHPEGKYVVDIDKSIDITKITPSTRVALRNDSYVLHLVLPSKVDPLVNLMKVEKVPDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGSGNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNEESRFDILKIHSRKMNLMRGIDLKKIAEKMNGASGAELKAVCTEAGMFALRERRVHVTQEDFEMAVAKVMKKDTEKNMSLRKLWK
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
What are the official names of this protein?
26S proteasome regulatory subunit 8 homolog A, 26S proteasome AAA-ATPase subunit RPT6a, 26S proteasome subunit 8 homolog A, Regulatory particle triple-A ATPase subunit 6a.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YBJX_ECOLI
Sequence: MVKSTPCITIDFMNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRECMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
What are the official names of this protein?
Uncharacterized protein YbjX.
What is the protein family that this protein belongs to?
To H.influenzae HI_0461.
Protein: COXX_CERS1
Sequence: MTDIRITGIPKEAGFGDYVALLKPRVMSLVVFTALVGLLVAPVTVHPMIALTGILFIALGAGASGALNMWWDEDIDRVMKRTRNRPVPSGTVAPGEALGIGLALSGIAVVMLGLATNLFAAGLLAFTIFFYAVVYSMWLKRTTPQNIVIGGAAGAFPPMIGWAVATGGVSVESLFMFALIFMWTPPHFWSLALFMKSDYSDAGVPMLTVTHGRRVTRAHVLVYSLLLAPLAVAGAFTGIGGPLYLATALALNGWLLVGAVRIWRRDEAQAEADRYRVEKGFFRFSLYYLFLHFGAILAEAALKPYGLGGW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL19_CUPNH
Sequence: MNIIEQIEKEEIARLTANKTIPAFAPGDTVVVSVNVVEGNRKRVQAYEGVVIAKRNRGLNSSFIVRKISSGEGVERTFQLYSPLIAAIEVKRRGDVRRAKLYYLRQRSGKSARIKEKLVSKAAVAAKAAQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.