PharMolix/UniProtQA huggingface dataset:
Protein: SYA_STAA1
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVVEKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_ECOUT
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLE1_DANRE
Sequence: MPSENLRWETLEALKNSPKGKLKYSPDWVEKGEDVLAGCVEVPSLSPLSGQILKRMSPRMLLKNCSRSSSVRDTSPGLSEEAAVCRSAPISPRLKRSSCSLPAVSIQTEEEEEKEEEEKAEVVVEAPAVSPEASVSTPPAVSVLSPRATQISGCIRMCEQKHKAKAKMELSLRQEQQERLVATVANHESEQLKRFEEFMELKQRQEHQSIRDTNEKEAQESLGRQEKLREEHRHRMKILNLRLREMEQQRLREVELERQRQVEGRERHRAINAIQEEVLQLNRLLQPQQSTHAEVEHAPYITRGNQLCSQLSEVVPAAADDQFPSVEDLSVAERALQEMRSLVRSLQEAVSQAAERKKKKEQEEEEEKRRQEQLKAQQEEQKKSAALSAKEKAKKEGLQTGADDSTLKWYNSLQDLANQCAQAFDDLNKAKDTQTKKLKMELQKAATTPVSQIANSSGAPLKEAFEKIDKLLSRRPVTSAGKTVSTSQHPQGLEFASYRLAEKFVKQGEEEVASNHSAAFPIGAVASGIWELHPKIGDLILAHLHKKCPYAVPHYPPMESGTSVEDYQKILGYRVDEGKVEGQDSFLKRMSGMIRLYAAIIQMRWPYSSKQGLHLHGMNHGWRWMAQILNMEPLADITATILFDFLEVCGNALMKQYRVQFWKLILIINEEYFPRYLCFASILHFTCIHWLQNIE
What is the function of this protein?
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.  May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity).
What are the official names of this protein?
mRNA export factor GLE1, GLE1 RNA export mediator, GLE1-like protein, Nucleoporin GLE1.
What is the protein family that this protein belongs to?
Belongs to the GLE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nuclear pore complex.
Protein: UPPS_SULAC
Sequence: MAKDVITRALLRPIYKIYEKILWSQIKDGPFPFHVGIIPDGNRRWARNNRLPLDQGYYTGYVKLRDVLTWILEIGISTVTVFALSAENCEKRTQQELSMIFKYLKIGLDELLTSDLVHKYQVRVKAIGMLDKLPEDLKKLVVDLESTTEKYNKKKLILAICYGGRQEILDAIRKIMNDYKLGIIDSKSIDESTFRKYLYDQELSDIDLLIRSSGEIRISNFLLWHLAYSELFFVDVYWPDFRKIDLWRAIRSFQKRKRNFGA
What is the function of this protein?
Generates tritrans,heptacis-undecaprenyl diphosphate from isopentenyl pyrophosphate (IPP) and geranylgeranyl diphosphate.  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (GGDP specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RTFL3_ORYSJ
Sequence: MEDERWKLSSSKGRSKSGRSCSSSSNYYYHSSDFNSSNATTLSRSYSASVTASRHATTAWSAAGAGGGGASSSSSSQHQHQQQQQQSNNSQRLSKKCVEAVKEHRARFYIVRRCVSMLVCWRDY
What is the function of this protein?
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs (e. g.  leaves and petioles).
What are the official names of this protein?
Small polypeptide ROTUNDIFOLIA LIKE 3, OsRTFL3, Small polypeptide ROT-FOUR-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the DVL/RTFL small polypeptides family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MS18A_HUMAN
Sequence: MAGVRSLRCSRGCAGGCECGDKGKCSDSSLLGKRLSEDSSRHQLLQKWASMWSSMSEDASVADMERAQLEEEAAAAEERPLVFLCSGCRRPLGDSLSWVASQEDTNCILLRCVSCNVSVDKEQKLSKREKENGCVLETLCCAGCSLNLGYVYRCTPKNLDYKRDLFCLSVEAIESYVLGSSEKQIVSEDKELFNLESRVEIEKSLTQMEDVLKALQMKLWEAESKLSFATCKS
What is the function of this protein?
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
What are the official names of this protein?
Protein Mis18-alpha, FAPP1-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the mis18 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
Protein: PLSB_HAMD5
Sequence: MSDRCKIYYQSLYLFVKIFIKSKLIPKNFVTDSGLDSSSPIFYILPSRSKMDLIILREESLKQGLPDPLTPLKVDEIQIPRYLFIDDIKESHGHSPSSAETLFSRYLGLYSKNSTLDITILPVSVMIGRRPISICQNRKINRLQKFFTAFWLGRDSFVHFSNPISLSRIINAHSKDLRIVYKLARVARIHFFRQYLSSVGRALPVHSDLFKKLLSSEAIEKALLDEARSKKISPQKAHDNALRLMKEIASQVSYETIRLSDRVLGWMWNRFYQGIHVHNADCVRQLAYKGHSIVYVPCHRSHMDYLLLSYVLYYEGLATPHIAAGINLNFWPAGAIFRRLGAFFIRRNFKGNKLYSTIFRAYLDELFTGGYPVEYFIEGGRSRTGLLLEPKTGTLSMTIQAMLRDISPSITLIPVYIGYEHVIEVLSYTKELRGERKKKENFFQMIGGLRQLRHLGQGYVNFGEPIQLKLYLDKNVPDWRESIRPINKIEATRPHWLASTVKDLAYQIMININHAAAINAINLCSTALLASENQALTRPELLEQLNCYLQLMRHAPHNQYSSVTDQMPEELLDHALHMNKFVVQKNHPHERICLPKEQVPLMRYYRNNIQHLLILPSLIATTVLCHHNISRQEIIRQITLLYPVFKIRWFLYYSEKQLLEALNLLMDELIRQKCVENKNHHFVVNLSSGMMTLKILASGIKEILQHYSIIFFLLTVYPDIDRKSLEKESRAMAKHLCILENMPSAEFFHSSIFSGLLTLLFEKREKMVSNDYSAQKNIEEIFNILKGLISSQMISVMQENFSLKKEWLTYKKKTTD
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TED6_ARATH
Sequence: MASTDSVYRPTPTPDHDTTVVVVVFVSLGCVMFLAFLAFVIWFLIKKRSRKHRERSEAVRVDEHFKMKEAIVEGPNGQKSVVLSVEDDVKIEDAIKREEKDLKKDGGVGSSVVSRS
What is the function of this protein?
Involved in the secondary cell wall (SCW) formation of vessel elements (e. g.  protoxylem and metaxylem), thus promoting tracheary element (TE) differentiation.
What are the official names of this protein?
Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, cell wall.
Protein: RUTF1_METEP
Sequence: MTDSESAAAVSVDAAAYREAMSRLASAVHLITTDGPGGRAGFTASAVCSVSDAPPTLLVCINRASSAYAALTQNGTLCVNTLGEGHETVASLFGGRTPVDERFAAGTWRRLRSGAPALADALVSFDCRIVGRHAVGSHDVLYCAVEAVAASGEADALLYSERRYRTLPRTPRSGSAPAEPARAPRAVGARPAEGPALALRSA
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF 1, FMN reductase 1, NADH-flavin reductase RutF 1, NADH:flavin oxidoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: YQGB_SHISS
Sequence: MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII
What are the official names of this protein?
Uncharacterized protein YqgB.
What is the protein family that this protein belongs to?
Belongs to the YqgB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHLB2_BOVIN
Sequence: MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS
What are the official names of this protein?
Endophilin-B2, SH3 domain-containing GRB2-like protein B2.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGO15_ORYSJ
Sequence: MESHGDEGEPSAMAKPPKKLPMSRKGFGTRGQSIQLLTNHFRVSVRRMDGHFYHYHVEVKYEDGGPVEAKGVCRRVVDKLQETYASELAGREFAYNGEKGLFTAGALLQTKHQFVVVMEDASSSGRTTTRRSSGGDDGSPGGSDRKRMKRPMAVKKFMVEISFAAKDPMSAIAEVLRGQETENSMEALRVLDITLRQHSAKHARDTASCPSYPSAMDGWMKTGVPKGGREKISCRGFHSSFRPTDSGLSLNVDVSTTMIVRPGPVIEFLLFNQNIKNPHEIDWGKAKCALKNLRIKTTHTGSEFRIIGLSEDTCYSQTFQIKRKNGNGGSDTVEEVTVFEYYRKNWKIDLKGSAHFPCLNVGKPKRPTYIPLELCHLVPLQRYKKALSTLQRSTLVERSRQNPQERMFVLSGVLRDSDYNSVPMLRECGISIAQEFTQVAARVLPAPKLKSGDGEDIFARNGRWNFNKNRLIQPKRVQRWVVVNFSAQCNAHHLAQRLIHCGNLKGLPVDPEDHVFQERSHMGRERAETRVNDMFQQLLSGDKPSFVLCVLPERKNCDIYGPWKRMCLVKYGIVTQCLAPTKINDQYLTNVLLKINAKLGGLNSLLQIERNQAIPLLSKTPTIILGMDVSHGSPGRDDVPSVAAVVSSLEWPLISKYKASVCTQSPRLEMIDSLFKLVGNEDHVIIRESLMDFYNSSRGHKDGVSEGQFNQVLNIELAQIIKACEFLANEKNDSEWSPKFTVIVAQKNHHTKFFQTDRSNKVVNVPPGTVVDKGICHPRNCDFYMCAHAGMIGTTRPTHYHVLHDENNFTPDDLQELVHNLSYVYQRSTTAISGVAPICYAHLAAAQVSQFVRLDDAASEGSGDGGAPPRPVPELPRLHPDVRQSMFFC
What is the function of this protein?
Probably involved in the RNA silencing pathway.  May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
What are the official names of this protein?
Protein argonaute 15, OsAGO15.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: YQGF_CLAM3
Sequence: MRLGSRLAVDVGKARIGLARSDPHGLIATPVETVPRDPAGSADVRRILAVATEIDCAELVVGLPLALSGRATASTDDAEGFARRLADATEIPVRLVDERLSTVSAQGALRASGRGSRKQKPVIDQVAAVIILQHALETERAAGSPPGALVPRNRVDPDRHA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLG_ACIC1
Sequence: MATDRSVRIGLIGAGAIGEDHARRLSTVIRGADVVAVHDVDPSRAKTVATRFRDARVIPDGNSLIGDPDVDAVVVASAAPTHEAYVLAAIAARKPVFCEKPLATTAAGCLRIVEAEKAHGRRFVRVGFMRRFDPAYLGLKAELRSGAIGHPLLAHLAHRNPAVPSTLRTTDAIADSLVHEMDLVRWLFDTEIREVRAVAGRRNAKAGPDLHDPLLVLVRMATDVVVDVELSLNIGYGYHIRAEIVGENGTVALASEQPIVRRISGEERRPVAQHWKTRFAAAYDAELSEWVRDVSQGRVSGPSAWDGYAATLATDAAAESLRSDTAVAAFPGDVPTLYREP
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HLDE_MANSM
Sequence: MAQYSAQFNQAKVLVLGDVMLDRYWFGATNRISPEAPVPVVRVQENEERAGGAANVAMNIASLNVPVQLLGLTGLDETGKALTTLLQTQKIDCDFVRLATHPTITKLRILSRHQQLLRLDFEEDFKNVQSTELLTKLENAVKNFGALILSDYGKGTLNDVQQMIQIARKAKVPVLIDPKGTDFERYRGATLLTPNMSEFEAVVGKCDTEEDIIEKGLKLIADIELSALLVTRSEKGMTLLRPGQEAYHLPTEAKEVFDVTGAGDTVISVLATALADGRSFEEACFLSNVAAGIVVGKLGTSTVSTIELENAIHGRSSTGFGIMNEDELKVAVQLAKARGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNTDDSVKRLKGETRPINDLPSRMAVLAGLSSVDWLVAFDEDTPQRLIGEVLPDLLVKGGDYKPEDIAGSKEVWANGGDVKVLNFENGCSTSNVIQKIRELKD
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: ARMP4_ARMGA
Sequence: MALFSAYALAFSLLMIPLILYILRIGRRESGLPPGPSTLPLVGNLHQLPHGGLHLQFTAWAKEFGGIFSLKFGPGTVIVATSPRAVRELIDQKSASTSDRPPSHFSNVITGGNNIGFARYSDYWRRGRRVMHSMLTKKACVNHLTIQRAEASQLMYDYLVEPKEFVAHGQRYANSVITSILAGTRSPHHTSPLVTAFFQMQHEWTHLLTPGAHPPVDMVPFLKYIPGSWKQICAKMKVSQEELYGGMIDACAKRVERGIRNGCFLEGELENKDVDRGLLRGMCSALMEGGSDSTSIYLQSFILMLVAHPEVQAKARAEIDSVVGLDRLPDIEDMDNLPYVSAVIKEVLRLRPITALGAPHYSTQPEVVDGYVIPKNSMIFMNQWGMLHDPDSYDQPESFMPERFLTSPFGTKPGADDTGRSKDIYFGGGRRICVGMHFGQNSLAITSMYLIWAFNLTNAIDPQTKNPIPVDINEYDISLNTIPKPFKCDFQVRSEEHKRMVENAFAEARQVFAPFEQD
What is the function of this protein?
Cytochrome P450 monooxygenase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable).  The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene (PubMed:21148562).  The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity).  ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity).  The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity).  The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity).  The role of the NAD(+)-dependent enzymes remains unknown (By similarity).  Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity).  The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity).  Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity).
What are the official names of this protein?
Cytochrome P450 monooxygenase ARMGADRAFT_1018417, Melleolide biosynthesis cluster protein ARMGADRAFT_1018417.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TAL_CERS4
Sequence: MKFFVDSADVAAIAELNALGMVDGVTTNPSLILKSGRNILEVTKEICNLVSGPVSAEVVAAKAEDMIEEGRHLAEIAPNIAVKVPLTWDGLRACKVLSDEGRMVNVTLCFSVNQALLAAKAGATFISPFIGRLDDINLDGMELIADIRQVYDNYDFKTEVLAASVRTPNHVADCARIGADVITAPPAVIKALANHVLTDKGLDMFNADWAKTGQSILLK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_METSE
Sequence: MGAAYFDQFKVVDLIAITNSSMMMMLAVAVALILLKGNRLIPNRWQAVMESIYDHFHGLVKDNSGPQYFPFVFTLFIFIVFLNILGLFPYVFTVTVHIVVTLGLSFSIVIGVTLGGLWKFKWNFLSILMPAGAPLALAPLLVLIETVSYISRAISLGVRLAANLSAGHLLFAILAGFGFNMLTTAGVFNIFPVLIMVFISLLEAAVAVIQAYVFSLLTTIYLADTIVLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TIM10_NEUCR
Sequence: MFGLGRPQPTSAEKIAAVENELKVVAEMHSRMVKICTLKCIDKSYREGDLSKGESVCLDRCAAKFFETHQKISDQLQKETQARGGGGFGM
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: PSBC_GOSHI
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MB211_XENTR
Sequence: MVAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHTLAGKQSSAESDAWVLQFAEAENRLQLGGCRKKCLSLLKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL
What is the function of this protein?
Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity).  It is unclear whether it displays nucleotidyltransferase activity in vivo.  Binds single-stranded RNA (ssRNA) (By similarity).
What are the official names of this protein?
Putative nucleotidyltransferase MAB21L1, Protein mab-21-like 1.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAC_YERPP
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: VATA_CAEEL
Sequence: MAAESSYGFVYGVSGPVVTAEKMAGSAMYELVRVGHQELVGEIIRLEGDYATIQVYEETSGVTIGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDIADITQSIYIPKGVSTNALSREARWDFVVSKDLRVGGHVTGGDIIGTVDENLLIKHKILLPPSACGTITFVAPSGQYTVEDTLLELEFAGRKQKFSMLQIWPVRSPRPVTEKLAANNPLLCGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDAIIYVGCGERGNEMSEVLRDFPELTMEVEGVTTSIMKRTALVANTSNMPVAAREASIYTGITLAEYFRDMGLNVAMMADSTSRWAEALREISGRLGEMPADSGYPAYLAARLASFYERAGRVKCLGSPEREGSVTIVGAVSPPGGDFADPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSEYMRALEEFYEKNYPEFVSLRTKCKEILQEEEDLSEIVQLVGKASLAESDKVTLEVAKIIKDDFLQQNGYTKYDRFCPFYKTVGMLKNMIGFYDLARHAVEATAQSDNKITWNVIKDSMGDLIYQLSAMKFKDPVADGEAKIRKDYEDLAEAMANAFRNLED
What is the function of this protein?
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad (PubMed:29168500).  This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization (PubMed:29168500).  The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates (PubMed:29168500).  Lysosomal acidification also leads to changes in mitochondrial morphology and function (PubMed:29168500).  Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity (PubMed:29168500).  In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance (PubMed:29168500).  Involved in receptor-mediated endocytosis (PubMed:16785323).
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar H ATPase protein 13, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.