PharMolix/UniProtQA huggingface dataset:
Protein: PLCB1_HUMAN
Sequence: MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
What is the function of this protein?
Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors (PubMed:9188725).  Regulates the function of the endothelial barrier.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, PLC-I, Phospholipase C-beta-1, PLC-beta-1.
What are the subcellular locations of this protein?
Nucleus membrane. Cytoplasm. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
Protein: CATA2_GOSHI
Sequence: MDPYKFRPSSSFDSPFWTTNSGAPVWNNNSSLTVGARGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISQLTCADFLRAPGVQTPLIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDIGVPQDYRHMDGSGVHTYTLINKAGKSHYVKFHWKPTCGVKSLLEDEAIRVGGANHSHATQDLYDSIAAGNYPEWKLFIQIMDPLHEDRFDFDPLDVTKTWPEDIFPLQPMGRMVLNKNIDNFFAENEQLAFCPSLIVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLQLPANAPKCAHHNNHHEGFMNFMHRDEEVNYFPSRYDPVRHAEKHPIPSTVLSGKREKCIIGKENNFKQPGERYRSFSADRQERFINRWIDALSDPRVTHEIRSIWISYWSQADKSLGQKIASRLNVRPSI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: UXAC_KLEP3
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDPIDSLEHHAVVAKDTSFDIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHALDVVLFAEATDAELDAILARRLAGETLSAHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RL2_FRACC
Sequence: MGIRRYKPTTPGRRGASVADFVEITRDHPEKSLVRPLHSKGGRNVHGRITTRHQGGGHKRAYRVIDFRRDKDGVPAKVAHIEYDPNRTARIALLHYLDGEKRYILAPVKLRQGDTVSSGVGADIKPGNALPLRNIPTGTVVHAIELRPGGGAKIARSAGTSVQLVAKDGPYAQLRMPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRMRWKGRRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVNPKGRPEGRTRATRKSSDALIVRRRKQNRRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TPM_MACRS
Sequence: MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANNRAEKSEEEVFSLQKRMQQLENDLDSVQEALLKANQHLEEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin Mac r 1.0101, Major allergen Mac r 1.0101.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: P3P_LACLS
Sequence: MQRKKKGLSILLAGTVALGALAVLPVGEIQAKAAISQQTKGSSLANTVTAATAKQAATDTTAATTNQAIATQLAAKGIDYNKLNKVQQQDIYVDVIVQMSAAPASENGTLRTDYSSTAEIQQETNKVIAAQASVKAAVEQVTQQTAGESYGYVVNGFSTKVRVVDIPKLKQIAGVKTVTLAKVYYPTDAKANSMANVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDMRLSDDKDVKLTKSDVEKFTDTAKHGRYFNSKVPYGFNYADNNDTITDDTVDEQHGMHVAGIIGANGTGDDPAKSVVGVAPEAQLLAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDPELAAVQNANESGTAAVISAGNSGTSGSATEGVNKDYYGLQDNEMVGSPGTSRGATTVASAENTDVITQAVTITDGTGLQLGPETIQLSSHDFTGSFDQKKFYIVKDASGNLSKGALADYTADAKGKIAIVKRGEFSFDDKQKYAQAAGAAGLIIVNTDGTATPMTSIALTTTFPTFGLSSVTGQKLVDWVTAHPDDSLGVKITLAMLPNQKYTEDKMSDFTSYGPVSNLSFKPDITAPGGNIWSTQNNNGYTNMSGTSMASPFIAGSQALLKQALNNKNNPFYAYYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPRRQGAGLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFTNRTTHELTYQMDSNTDTNAVYTSATDPNSGVLYDKKIDGAAIKAGSNITVPAGKTAQIEFTLSLPKSFDQQQFVEGFLNFKGSDGSRLNLPYMGFFGDWNDGKIVDSLNGITYSPAGGNFGTVPLLKNKNTGTQYYGGMVTDADGNKTVDDQAIAFSSDKNALYNEISMKYYLLRNISNVQVDILDGQGNKVTTLSSSTNRKKTYYNAHSQQYIYYNAPAWDGTYYDQRDGNIKTADDGSYTYRISGVPEGGDKRQVFDVPFKLDSKAPTVRHVALSAKTENGKTQYYLTAEAKDDLSGLDATKSVKTEINEVTNLDATFTDAGTTADGYTKIETPLSDEQAQALGNGDNSAELYLTDNASNATDQDASVQKPGSTSFDLIVNGGGIPDKISSTTTGYEANTQGGGTYTFSGTYPAAVDGTYTDAQGKKHDLNTTYDAATNSFTASMPVTNADYAAQVDLYADKAHTQLLKHFDTKVRLTAPTFTDLKFNNGSDQTSEATIKVTGTVSADTKTVNVGDTVAALDAQHHFSVDVPVNYGDNTIKVTATDEDGNTTTEQKTITSSYDPDMLKNSVTFDQGVTFGANEFNATSAKFYDPKTGIATITGKVKHPTTTLQVDGKQIPIKDDLTFSFTLDLGTLGQKPFGVVVGDTTQNKTFQEALTFILDAVAPTLSLDSSTDAPVYTNDPNFQITGTATDNAQYLSLSINGSSVASQYVDININSGKPGHMAIDQPVKLLEGKNVLTVAVTDSEDNTTTKNITVYYEPKKTLAAPTVTPSTTEPAKTVTLTANSAATGETVQYSADGGKTYQDVPAAGVTVTANGTFKFKSTDLYGNESPAVDYVVTNIKADDPAQLQAAKQELTNLIASAKTLSASGKYDDATTTALAAATQKAQTALDQTNASVDSLTGANRDLQTAINQLAAKLPADKKTSLLNQLQSVKAALGTDLGNQTDSSTGKTFTAALDDLVAQAQAGTQTDDQLQATLAKVLDAVLAKLAEGIKAATPAEVGNAKDAATGKTWYADIADTLTSGQASADASDKLAHLQALQSLKTKVAAAVEAAKTVGKGDGTTGTSDKGGGQGTPAPAPGDTGKDKGDEGSQPSSGGNIPTKPATTTSTTTDDTTDRNGQLTSGTSDKGGGQGTPAPAPGDIGKDKGDEGSQPSSGGNIPTNPATTTSTTTDDTTDRNGQLTSGKGALPKTGETTERPAFGFLGVIVVSLMGVLGLKRKQREE
What is the function of this protein?
Protease which breaks down milk proteins during the growth of the bacteria on milk.
What are the official names of this protein?
PIII-type proteinase, Cell wall-associated serine proteinase, Lactocepin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: COAE_LACAC
Sequence: MTYVLALTGGIATGKSTADQFFKNKNIPVVDCDQIAHDLMKPKNASWQAIKDNFGTEYLNSDQTINRKKLGQLVFSDPTALNKLNQLTHPLIFDKTIQKIKMYQDKDIVILDAPVYFESNLDKKKIANGVLVITLPEATQINRLKQRNNLTDEEAKMRIKSQMPLNKKAQMADFVIANTGTIEELENKLEQLLIKIKEEG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_COXB1
Sequence: MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGKDLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPPHAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLENRIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGDCFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAQRIGFKVASQLLEQGGDSLLRELKQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SYR_RICRO
Sequence: MNIFNQLKQDIIVASKQLYNNQAIANTATIDIPKDSFNGDLSSNVAMIIAAKESIAPREVALKFKEVLITLPYIASIEIAGPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVSYSVTKEYYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYDERFKIIKSFAVEKMLDLNRKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLESMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKADGSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNNEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFESGKYDLSLLSSEEEIEIIKLLVSWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSEYRFVIESNKELTLARLALASAIQKVIASGLEVIGVEPMNKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_NEIMA
Sequence: MSNIEQQVKKIVAEQLGVNEADVKNESSFQDDLGADSLDTVELVMALEEAFGCEIPDEDAEKITTVQLAIDYINAHNG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YVKA_VACCC
Sequence: MGHIITYCQVHTNISILIRKAHHIIFFVIDCDCISLQFSNYVHHGNRFRTVLISKTSIACFSDIKRILPCTFKIYSINDCP
What are the official names of this protein?
Uncharacterized 9.4 kDa protein.
Protein: MIAB_SINMW
Sequence: MTQETALLPTSPEAGDLNVPARKVFVKTYGCQMNVYDSDRMSDALSRDGYVATDVLEEADFVLLNTCHIREKAAEKVYSELGRLRDLKKAKAREGREMLIGVAGCVAQAEGKEILRRAPAVDLVIGPQTYHRLPEALRRARTGERIVETDYAIEDKFVHLPAPDKAKTRARGVTAFLTVQEGCDKFCTFCVVPYTRGSEVSRPVAQIVAEAEKLVEGGVREITLLGQNVNAWHGAGPHGREWGLGDLLRRLGEIEGLARLRYTTSHPRDMDDSLIEAHRSMAKLMPYLHLPVQSGSDRILKAMNRRHTAAEYLALVARIRAVQPDLALSGDFIVGFPGETDEDFEDTLRLVDAVNYAQAFSFKYSTRPGTPGAELEQQVPEDVKAKRLEILQALLIKQQRGFAEACVGREIDLLLEKPGRMPGQLVGRSPWLQPVNVDAKASQIGDIIRVRITKAGPNSLFAEMIGETEARS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP30_RAT
Sequence: MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLSLLKALSCQEVTEEEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHPTTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSQGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATESPGSALGVQDTQAAPKPGLSQPAAPKTQFFMNGACSPSLLPALPSPMAFPLPVAPDYSSSMYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE
What is the function of this protein?
Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:24896179).  Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling.  Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (By similarity).  Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 30, Deubiquitinating enzyme 30, Ubiquitin thioesterase 30, Ubiquitin-specific-processing protease 30, Ub-specific protease 30.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: VLP19_BORHE
Sequence: MRKRISAIIMTLFMVLVSCNSGGVAEDPQSKFLKSVIDLGNDFLNVFTSFGDIVSKVLGFSTETKKSDVGAYFKTIQDTIQGTKDKLNKIVTDMKREGNPNASATETAVKTLIDNTLDKIIEGAKTVSDAIGDASDPIANVAAQNAAGAAGTEVDKLVKGIKTIVDVVLKGVGSANAGDDKKAEDGNTARTAAAGDGEAGKLFTAGAGAAGDANNAKKVAADAAKAVGAVTGADILQAMIKDNGDAAKLATAQNAGAAPKDGAIAGGIALRVMAKGGKFAGPSAAADDAVTAIKGAAISAITKALDTLTIAIRKTIDAGLKTVKEAMKINANDTPISPEQNTPKATTNN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 19.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Gamma subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GLYA_NEIGO
Sequence: MFSKSVTLAQYDPDLAAAIAQEDRRQQDHVELIASENYVSCAVMEAQGSQLTNKYAEGYPAKRYYGGCEYVDIVEQLAIDRVKELFGAAYANVQPHSGSQANQAVYASVLKPGDTILGMSLAHGGHLTHGASVNISGKLYNAVTYGLDENEVLDYAEVERLALEHKPKMIVAGASAYALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRGGVILCRDNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEALQPEFKQYAKQVKINAAVMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKAHITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNETDARVLSNLVADVLANPEDEANLAKVCGQVTALCDKYPVYGN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_RICPR
Sequence: MLAIGITGSYASGKTFILNYLSAKGYKTFCADRCIKELYKDIVLQTQILKILPELEYFNIRKISNLIYNNDIAREKLQNFIYPLLIDKLILFKKENTNYKLAFSEIPLLYEAKFEQYFDFVVTIYCSEEIRMQRAITRAEFDINIYNKIKEIQLSQESKIAKADFSINSGVDMLDLEKQITKLIKDLECRV
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_CAMFF
Sequence: MPTINQLVRKERKKVIVKSKSPALKECPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRPKDAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SELA_SHIDS
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPTWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGVEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGSFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEFC_SALTY
Sequence: MSFHHRVFKLSALSLALFSHLSFASTDSELNLDFLQGMSAIPSVLKSGSDFPAGQYYVDVIVNQENVGKARLSITPQEESANALCLSPEWLKAAGVPVRLEGYASTLNAAGQCYVLSRNPYTRVDFSYGSQSLVFSIPQSFLVGKTDPSRWDYGVPAARLKYSANASQTSGQSTSAYANADLMVNLGRWVLASNMSASRYADGSGEFTARDITLSTAISQVQGDLLLGKSQTRSALFSDFGFYGAALRSNSNMLPWEARGYAPLITGVANSTSRVTISQNGYAVYSKVVPPGPYQLDDVRSVGNGDLVVTVEDASGHKTTTVYPVTTLPTLLRPGEVEYNVAVGRKSSNYKLKKPFADGENGMFWMGSVGYGFDSTTLNAASILHGKYQAGGVSVTQALGGFGAVSAGMNLSQAKYDNGDNKRGHSVSAKYAKSFSDSSDLQLLAYRYQSKGYVEFADFYSTDRYTRYNTKSRYEMRFSQRLGNSNLNLAGWQEDYWWMKGKAIGGDVSLSTTILDGVSVFLNGSYSKRPYLDKPDYSTSLSFSIPFTLGGVRHYSSTGLSYSSSGRMGMNSGVSASPTDRLSYGLNTNLSDKGDRSLSGNLSYGFDAIQTNMMLSQGRDNTTVSGSVSGTILGTADSGLMMTKETGNTLGVARIPGVKGVRINGSAPTNSKGYTVVNLSDYSLNRVSVDMENVPDDLELQTTSFNVVPTEKAVVYREFGAEHVLRYILRVKERDGRILNGGSAQTEQGLDAGFIAGNGVLLMNMLSAPSRVSVERGDGSVCHFSVKGIVPNTGKVQEVYCE
What is the function of this protein?
Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein PefC.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: FTSZ_HALH5
Sequence: MLEFEMDMDQLAQIKVIGVGGGGSNAVNRMIENGLQGVDFISVNTDAQALHLSKAEVKLQLGGKLTRGLGAGANPEIGKKAAEESREQIEEALQGADMVFITAGMGGGTGTGAAPVIAEVAKEIGALTVGVVTRPFTFEGRKRSTQAAAGIAALKEKVDTLIVIPNDRLLEIVDKNTPMLEAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIMKDKGSALMGIGIATGENRAGEAAKKAISSPLLETSLDGAQGVLMNITGGSNLSLYEVHEAAEIVSAASDAEVNMIFGSVINEDLKDEIVVTVIATGFDDAENRRAQQQSNFNRQAAPKQPLKSKEKEAEKKEPRFTSQPEADDNESLDTLDIPAFLRNRRRKSR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
Protein: DEF_ECOL5
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS10_STRPQ
Sequence: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ATPD_PSEPW
Sequence: MAELTTLARPYAKAAFEHAQAHQQLANWSAMLGLAAAVSQDDTMQRLLKAPRLTSAEKAATFIDVCGDKFNAQAQNFIRVAAENDRLLLLPEIAALFDLYKAEQEKSVDVEVTSAFALNQEQQDKLAKVLSARLGQEVRLHASEDANLIGGVVIRAGDLVIDGSVRGKIAKLAEALKS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THF1_ACAM1
Sequence: MNNLRTVSDTKRAFYSIHTRPVNSVYRRVVEELMVEMHLLRVNEDFRYDPIFALGVTTSFDRFMDGYQPENDKDAIFSAICKAQEADPVQMKKDGQRLTELAQSKSAQEMLDWITQAANSGGDELQWQLRNIAQNPKFKYSRLFAIGLFTLLELSEGNITQDEESLAEFLPNICTVLNISESKLQKDLEIYRGNLDKIAQVRQAMDDILEAQKKRREADQAKKEGSDDTPTTEASTPDSEPTSEVSS
What is the function of this protein?
May be involved in photosynthetic membrane biogenesis.
What are the official names of this protein?
Protein Thf1.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
Protein: DER_GEOMG
Sequence: MMPLVAIVGRPNVGKSTLFNRLVGRRKAIVDDMPGVTRDRNYETVTRFEAPFILIDTGGFEPVSEDRLLQQMREQSQLAMEEADVIIFLMDGRAGLTPSDVEVVEMLRRVKKPVFFVVNKVDGEKIENEAADFYTLGIGTLHTISAEHNRGVNDLMEEVVAALPKSSTRLDDEDITRIAVVGRPNVGKSSLVNRLLGFERVVANPTPGTTRDSVDTLFACNKKRYLLIDTAGIRRKGKTTQKLEKYSVVDSLRSIERADVVLIIINAEEGVTEQDERIAGYAFEAGKACIFVVNKWDTLAKDNSTLGKFVDQIKTEFKYLSFAPIVFVSAKSGQRINRVMEEVERVMAQYSKRVSTSDLNRVFSEAVEKHHAPLSHGRRVKFYFATQVGTKPPTFVLFTNQPEGVHFSYERYLMNKFREAFDFTGSPLKIIFRGRDRRE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYE1_THEP3
Sequence: MNNLRVRFAPSPTGAIHIGNIRTALFNYLFSRSEGATFVLRIEDTDLERSSKEFEELIFKELEWLGIEWDEGPDKPGPYGPYRQSERLEIYHKFAQKLIEEKKAYRCYCTPEELEEDRRKAVERGDIPCYSGRCRYLTKEQEEAFIREGRKPVIRFIIPDDEVIEFEDMIKGKITIKSDTLGGDMVIVKSDGMPTYNFAVVIDDALMKITHVIRGEDHIYNTPKQILIYKALGFEIPKFAHAPLILGPDRTKLSKRHGNTYIGQYRELGYLPEAMFNFLSLLSWSPEDNVEIMSKEEIIKKFNFRRIHSANPVFDIEKLNWMNQQYIQKSSIERIVDLAIPHLRRAGYIDGIDDMVYNWLKDVISLYKDGLQYVAQITEKAKMFFVEEVEYSDETVKILNSPNSKIVLEVVKKVIEEADEITEEYVKDLLKKLQKETKVKGKEFFMPIRVAITGEDHGPELVKIIPLLGKDKVINRLKKAINLIK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.