PharMolix/UniProtQA huggingface dataset:
Protein: GATB_OSTLU
Sequence: MTTKQPTRFEAVIGIETHVQLNSRTKAFCRCAYEYGAEPNTRVCPTCMGHPGTLPVLNSAVVKKGIAIGTALGAKIRRTSKFDRKQYFYPDLPKGYQISQFDEPLCYDGSIDVVLPVEDGGEVKRVGITRAHLEEDAGKLTHAKGEDGKKYSYADFNRAGVALLEIVTEPDLRTGREVAAYGSELRRIVRFLDACDGDMSRGSMRNDVNVSIRPVGRERFGTKVEVKNMNSFNAMARAIDYEIARQEELIRSGRGDEIVQETRTWDEAAQKTVAMRKKEGLADYRYFPEPDIPKLRLSEEFISNVVASMPELPSMVRARYAALGLPPADVQVLVEDKELVTYFDAALSSSAKPSAKQVANWLTGDIMAHLKNSKMENVSQLPLSPEALGEFCAMIDAGEISGKIGKDLLPELLEKGGSAKKLVADRGLSQVSDPREIEALVDGVLEANAGQLEQYRAGKTKLKGFFVGACLKASGGRANPSLVDRILQAKLDGVPIDVA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: RL15_NATPD
Sequence: MSKKRRQRGSRTHGGGSHKNRRGAGHRGGRGNAGRDKHEFHNHEPLGKSGFKRPQKTRRDVETVNLRELDEDIAVLVEDGIAEESDDGYVVDARDVVEDGYEADVVKVLGAGTVYNELEIVADAFSESAEQALEVADGEAVLSERGEELEAEKDSTDEEDEES
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YQGB_SHIF8
Sequence: MKKKPVAQSERQHTLLENPCAYGLLSQFQAATVVNCFTLNKII
What are the official names of this protein?
Uncharacterized protein YqgB.
What is the protein family that this protein belongs to?
Belongs to the YqgB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH_RICPR
Sequence: MAAFTPITIAYGDGIGPEIMEAVLYILRKAEARISLETIEVGEKLYKKHYTSGISEESWDVIQRTGIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPVVSFYPFTRTLHPNLNLTIIRENEEDLYSGVEYRQTHNMYESMKLISHTGCKKIIRYAFEYAIKNNRKKVTCLTKDNIMKFSDGIFHRVFNEIAKEYPQINNEHYIIDIGTAKLATKPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIGQHYAMFEAVHGSAPDIAGKGIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVHTFDIYNEHSSSKKVCTKEFAVEVIKRLGQLPITLPKAAYPLIVKKQESNIDYKIDTREVKKLVGTDIFINMHVFSAHDIADKINKLDIGNFELKTISSKGLKLWPHDSRFEIISDHWCCRFMNKDGTEIKHLDITMLLQSLSKANIDFIKVENLFEFDGVAWYSLAQGE
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: RS16_ACHLI
Sequence: MAVKLRLQRFGNHKRPFYRIVAADAKAPRDGKFLEIVGTYEPIKGAVAVDSEKVQAWMNNGAQPTDTVKSLFKKFNVLNK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HIBCH_SCHPO
Sequence: MGLKLNISNDLKKSGFMLRQSLLKTSVSNFLSLNASSTMSRAFIRNPKFYSTSSNDTVLYESKNGARIFTLNRPKVLNAINVDMIDSILPKLVSLEESNLAKVIILKGNGRSFSSGGDIKAAALSIQDGKLPEVRHAFAQEYRLSHTLATYQKPVVALMNGITMGGGSGLAMHVPFRIACEDTMFAMPETGIGYFTDVAASFFFSRLPGYFGTYLGLTSQIVKGYDCLRTGIATHFVPKHMFPHLEDRLAELNTSDISKINNTILEFAEFASSSPPTFTPDVMDVINKCFCKNDTVDIIRALKEYASNTSALAEFAKSTVKTLYSKSPTSIAVTNRLIKSAAKWSISEAFYYDHIVSYYMLKQPDFVEGVNAQLITKTKNPKWSKSHEYHFKDLENYFKLPSEYNNGISFAAKGRRKTPLWNYKTYPYL
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has an indirect role in endocytic membrane trafficking.  May have a function in protein biosynthesis in mitochondrial small ribosomal subunit (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. Mitochondrion-specific ribosomal protein mS47 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TFDC1_DELAC
Sequence: MNERVKQVASALVDAIQKTLTEQRV
What are the official names of this protein?
Chlorocatechol 1,2-dioxygenase 1, TfdCI.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: RL27_BURCJ
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHAGENVGMGKDHTLFALVDGHVKFATKGADKKHLVIVVPAAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HFQ_POLSJ
Sequence: MSNNKGQLLQDPFLNTLRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVSFATGESEESPAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RIR2_VACCP
Sequence: MEPILAPNPNRFVIFPIQYHDIWNMYKKAEASFWTVEEVDISKDINDWNKVTPDEKYFIKHVLAFFAASDGIVNENLAERFCTEVQITEARCFYGFRMAIENIHSEMYSLLIDTYVKDSNEKNYLFNAIETMPCVKKKADWAQKWIHDSAGYGERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHPPSEETVRSIITDAVSIEQEFLTAALPVKLIGMNCEMMKTYIEFVADRLISELGFKKIYNVTNPFDFMENISLEGKTNFFEKRVGEYQKMGVMSQKDNHFSLDVDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit, Ribonucleotide reductase subunit 2, RNR2.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: UL96_HHV7J
Sequence: MSLHELIKQTMSKNLEKKHYELLKLKLGEDHPLSVRQQIHALNQNLVSENLEQSQIITSLTKMLKDQKLQLKAQRKNAAQLECVDLDDILDTAAEVKSVTDNIKETLLAGLESD
What are the official names of this protein?
Protein U68.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL96 family.
Protein: RK31_PORPU
Sequence: MAKVDIHPIWYPDAKVYCDGQLIMTIGSTKPELHVDIWSGNHPFFTGSQRIIDTEGRVERFMRKYKMEKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTGA_ECOLU
Sequence: MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMAERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRGRQAWILRQMYQLGGESFMQQHQLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NCPP_YERPA
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVVEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: GSA_RALSO
Sequence: MSSPSRSVSLFERAQKTIPGGVNSPVRAFRSVGGTPRFIAKAAGPYLWDADGTRLIDYVGSWGPMIVGHAHPEVVRAVQQVAADSFSFGAPTEAEVVMAETLCELVPSIEQVRLVSSGTEATMSALRLARGFTGRDLIVKFEGCYHGHADSLLVKAGSGLLTFADTTQNAPSSAGVPEDVVKHTMVLPYNDADALREAFARHGKEIAAVIVEPVAGNMNLVRATAAFLQAMRALCTEHGAVLIFDEVMTGFRVALGCAQALYGITPDLTCLGKVIGGGMPAAAFGGRRDIMGFLAPLGSVYQAGTLSGNPLAVAAGVTTLRLIAADGFHDRLAAQTRKLVDGLAGIARDAGVPFAADSVGGMFGLYFREGVPTSFAEVTQSDVGRFNAFFHAMLAEGVYLAPSAFEAGFVSSMHDDAVLEATFEAARRAFKAV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_ACIB3
Sequence: MSESKQFKRSVFFISDGTAITAETLGHSLLAQFPNVDFDIHIMPYITTEEAAMAVVVEINKCQTRDGCLPLVFDTLVDPHVREIINTAKAVNLDVFEGLISKLEQELGTPPTTLVGQTHAVTDSEYYKARIDAVHFALDNDDGARTRHYDKADLILIGVSRSGKTPTSIYLSLQFGIRVANYPLTEEDLDDNRLPAVLREHRSKLFGLMIDAERLVAIRSERKANSRYASFSQCQMELRAIEGIYISEGIKYLNVTEMSIEEISTRILQMTGLKRRIG
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: REG1_PYRAB
Sequence: MAGIDEIDEIIVRELRKNSRITLTELGKKVGLTASAVKNRIEKLEKLGVIKGYSAVVDTSFFGEFLTAIIEVELVDPEAPDLAKVLQPILRMRNISDVYKKSGEFQLAIRGTFRDVDSLNSFLKDLRKVYLKNLARRMRVSIVLENFKEAGVILK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PYRAB00550.
Protein: MEND_BACAH
Sequence: MNNHIEALSYYLGAFVDELTRLNVCDVVISPGSRSTPIALLMEQHEGMNTYLHVDERSAGFFALGIAKAKKRPVALLCTSGTAAANYYPAVCEAFHSRVPLIVLTADRPHELRDVGAPQAMNQINLYGTFVKQFTEMALPEASEAMYHYARMTTQRMIASACLAPQGPVHLNFPVREPLIPDFSLESLWDKGRGEYTGVVQQGNAVMPSEYVDSLVGRLSHMEKGLIICGDDSHSEIATFATQLAEKTGYPILADPLSNIRSGHHDKTMVIDCYDTFLRNELLKETWKPDVLIRFGGMPVSKALTQFIKKQTKAVHIVVDESGQWRDPALVATEVVQASDIAFCSALIEKMPVMKKNDWFRMWQHINEKTKETLREMETYDTAFEGRVITDIVRVLPEGATLFASNSMPIRDTDSFFFTSDKNIQVMANRGVNGIDGIISTALGASMICDPLVLVIGDLSFYHDLNGLLAAKLHELNITIVVVNNDGGGIFSFLPQYEKKEHFESLFGTPIGLDYEHVVTMYGGSFSRVNGWEQFREEVQKGATTEGLHVVEICTNRDENLTLHRKLWAKTQDVITTSLQGESK
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL11_METPE
Sequence: MAETVEVLVPGGRATAGPPIGPALGPLGINVKAVVDDINKKTAEFNGMQVPVKIEVDDKKNVTISVGIPPTTALVMKEVGIEKGSAEPNSIIVGDLPIEAAVRIARMKLDDMLSYELKTAVKEVIGTCVSVGVTVDGKKPKEILAAISAGQYDSVLEA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DXS_XYLF2
Sequence: MIDFTCYPRLSRIQTPEDLRAFQESELRAVADELRNYLIESVGLSGGHFAAGLGVVELTIALHYLYCTPIDQLVWDVGHQTYPHKILTGRRDKISTVKHQGGLAPFPKREESIYDTFGVGHSSTSISAALGMAIVAQRNGDERKVVAIIGDGAMTAGMAYEALNHAGGMSPAPNLLVILNDNRMSISEAVGGLTKMLGRATGSKALNAIREGGKRIFGDKKTNATARFLRRWEEHWKGMFVPSTLFEEMGFHYTGPIDGHDLPALLGALKTLRTLKGPQLLHVITTKGKGYELAEGDQIGYHAVAPFDPQKGLIKAGAKKQTYTDVFSEWLCDMAAVEPRLLAITPAMREGSGLVRFSQEYPQRYFDVAIAEQHAITLAAGMATQGAKPVVAIYSTFLQRGYDQLVHDVALQKLDVLFAVDRGGVVGPDGATHAGNLDLSFLRCVPNMMLMAPADEAECRKMLSTGFHYSGPVAVRYPRGTGPGVVPSAELDVLPVGVAQLRHSGTRIALLGFGVCVAPAEQVGRRLGLTVVNMRFIKPLDRTLLLELARTHEVFVTIEDNVVAGGAGSGVAELLNAEGIVLPIVHLGLPDAFQQHASREDLLAEAGIDAAGVYAALLSRWPDLAVQNHPLSAVS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: L2GL_DROPS
Sequence: MLKFIRGKGQQPTAERQRLQKDLFAYRKTAQHGFPHKPSALAYDPVAKLMAIGTQTGAIKVFGQPGVELYAQHTLVNNSAAELNVQLLEWVYGTGRILSLTAANQLILWEPVGTTLVPIKTLPFDGKLKKVSSLCCSLNKDLLWIGTEGGNIYQLDLKSFTIREPVIYHDVVLEQVPPTYKLNPGAIESIRQLPNSLNKLLIAYNRGLCVLWDMQTSAVERAYIAPGHGQSVGLSVNSTGTEFSWYHADGSYATWSIDNGEPPQNVNYVPYGPDPCKSINRLYKGQRGTNDVIVFSGGMPRSAYGDHNCVSVHVSDGHKVCLDFTSKVIDFFVTYKEGSDDVEVLIVLLEEELCAYDLTDPSILSIKAPYLHSVHASAVTCNYLASQVTQGVYERILRAGDEQDIDYSSIDWPITGGVLTDDSVESDEDEVVKDYEILLTGHEDGSVKFWDCTGVLLKPIYNFKTASIFGNEHEYREDGAADISAEQLDEGEPPFRKAGLFDPYSDDPRLAVKKIAFCPKTGQLVVGGTAGQIVIADFDTAAEDQSSLKYNSMNLVSDRDGFVWKGHDQLNVRANLLEDNAVPLTENGVNITGVLQVLPPASITCMALEANWGLVSGGTAHGLVLFDFKNFVPVFHRCTLNPNDLTGAGEQLSRRKSFKKSLRESFRKLRKGRSTRNNPTNQVPTTLEARPVERQIEARCTDDGLGSMVRCLLFAKTYVTNVNITSPTLWSATNASTVSVFLLHLPPAQTAATTVPPASGNVPPQASRRISAQLAKEIQLKHRAPVVGISIFDQTGSPVDQFNAGENGSPPHRLLIASEEQFKVFSLPQLKPINKYKLTANEGARIRRIHFGSFSCRISPELLQSLHSGSPTKSVRSHGEGDGAGNVSATSAAGRGDLYHEMALICLTNMGDIMVLSVPELKRQLNAAAVRREDINGISSLCFTNDGEALYMMSSSELQRIALSTSKVVQPTGIVEVEPLESEDNETASLVNDGNESDKDGEANKELANTASDTQPPVATLRAKPLELNADRSSLHLTNGISNSNSPNRANETITSSIGDITVDSVRDHLNTTTTTLCSTTTEETVGRLSVLSTQTNQATTTVNMKDIPDINIPNLMDLASKSNTTETSTSSVVIKSVITSISHEKTNGESENVTTKTTAHEESQF
What is the function of this protein?
Essential for the development of polarized epithelia, for cell polarity associated with asymmetric cell division of neuroblasts during development, and for oocyte polarity formation.  Promotes the formation of actin-rich projections at the oocyte cortex and the posterior enrichment of par-1 which is required for oocyte polarization.  Regulates the localization of axis-specifying morphogens such as stau and grk (By similarity).  Could act as a tumor suppressor.
What are the official names of this protein?
Lethal(2) giant larvae protein, p127.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space, extracellular matrix. Note=Intercellular matrix.
Protein: UBP16_MOUSE
Sequence: MGKKRTKGRSAPDTVASESAEPVCRHLRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKPEEEAEDPSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEVKYCSSNRLGQVVDYVRKQAGVRTSKPAEKNNGHIELENKKLEKESKNEQEREKSENLAKETIPMDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEVNLEPPGPLTLAMSQFLSEMQENKKRVVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEEVKNKVKDYEKKKAIPSFVDRIFGGELTSTIMCDECRTVSLVHESFLDLSLPVLDDQSGKKSINDKNVKMTMEEEDKDSEEEKDDSYMKSRSDLPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQERFLHFNELCATDYTEDNEREADTALAGEVEVDTDSTHGSQEEATQIELSVNQKDLDGQESMIERTPDVQESPEDLGVKSANTESDLGIVTPAPECPRDFNGAFLEERTSGELDIINGLKNLNLNAAVDPDEINIEIPNDSHSAPKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCSRRQCNGPKANIKGDRRHVYTNAKKQMLVSLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASCHLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL
What is the function of this protein?
Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator.  Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis.  In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes (PubMed:24034696).  Regulates Hox gene expression via histone H2A deubiquitination.  Prefers nucleosomal substrates.  Does not deubiquitinate histone H2B.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP16 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_BACC3
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PRU_MYXXA
Sequence: MNAIKTAVAAVTAAASLVAFSPAEAATATANLNVTANVGGACSIGSGAGGGTLNFGTYDPVVVNSALGVDLFGTGSLSVQCTLLSTAVITLGQGLYPAAGSTAAVPLRRMRNAASTDYLSYFLYMDVTRLIAWGNTSGTGLPFLGLGLPVPVQVYGTVPRGQNVPSGTYNDTVVATITF
What is the function of this protein?
A late-developmental spore coat protein.
What are the official names of this protein?
Protein U.
What are the subcellular locations of this protein?
Secreted. Spore, perispore. Note=Secreted across the membrane to assemble on the spore surface.
Protein: GNAT2_MOUSE
Sequence: MGSGISAEDKELARRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYAEPSCADAGRQLNNLADSTEEGTMPPELVDVIRKLWKDGGVQACFDRAAEFQLNDSASYYLNQLDRITDPNYLPNEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGNYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
What are the official names of this protein?
Guanine nucleotide-binding protein G(t) subunit alpha-2, Transducin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Note=Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark- adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
Protein: YITP_BACSU
Sequence: MQKSISFFVIFSILWGSLFLFSIIGSLGTTPIPLTKDSKFLMSSILPQGWGFFSKNPRDTAIGLYEAENASAKVRWPNMRADNLFGLYRYGRSQGVEMGVIYSQVGKEQWTACKEKDLGACKSKAKTVQLKTPAPRPLLCGSYYLTKEDIVPWSYSKYTPSSYQVKSIVKVVISCSKT
What are the official names of this protein?
Uncharacterized protein YitP.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL19_FUSNN
Sequence: MKEKLIELVEKEYLRSDIPQFKAGDTIGVYYKVKEGNKERVQLFEGVVIRVNGGGVAKTFTVRKVTAGIGVERIIPVNSPNIDRIEVLKVGRVRRSKLYYLRGLSAKKARIKEIVK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: UFAP_PIG
Sequence: MSHGKMPLVLSLVLILCGLFNSISCEKQQTSPKTITPVSFKRIAALSQKMEANYKAFAQELFKTLLIEDPRKNMIFSPVSISISLATLSLGLRSATRTNAIDVLDVALKNLAVMLMAQAPTALLEIVHELVNRTAKHQDILIDRTEMNQMFLKEIDRYIKMDIQMIDFKDKEKTKKAINQFVADKIDKKAKNLITHLDPQTLLCLVNYIFFKGILERAFQTNLTKKEDFFVNEKTIVQVDMMRKTERMIYSRSEELLATMVKIPCKENASIILVLPDTGKFNFALKEMAAKRARLQKTNDFRLVHLVVPKIKDNLQDRFKHLLPKIGINDIFTTKAVTWNTTGTSTILEAVHHAVIEVKEDGLTKNAAKDKDFWKVPVDKKEVPVVVKFDRPFFLFVEDEITRRDLFVAKVFNPKTE
What are the official names of this protein?
Uteroferrin-associated protein, UFAP.
What is the protein family that this protein belongs to?
Belongs to the serpin family. UTMP subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: UBIE_SHEB9
Sequence: MSEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSGARPGMKVLDLAGGTGDLTAKFSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVLKPGGKLLVLEFSKPQHEIMRKVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTDGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: GCH4_BORPE
Sequence: MNSPIDPAIVMPDVQSSTDTRHIPIQRVGIRGVRHPMLVLAGDGAAQPTVANWTLTVALPAEEKGTHMSRFVALLEKYRATPMTPALFAAMAREMLPLLHAERGDITASFPYFINKSAPVSGVQSLLDYEMQWIARAVGEQVEFELVAQVPVTSLCPCSKAISEYGAHNQRSHVTVSAIVDGDFRMDELIRLVEDEASCELWGLLKRPDEKYVTERAYDNPKFVEDLVRDVAARLKAHPGIGRFRVEAENFESIHNHSAYAVVEG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: DXR_PSYA2
Sequence: MVMTQRIAVLGATGSIGDSTLAILAAQPQYYDVYALSGYHRLDKLLALCQQFAPKRVGVPTTAVDDFAKRLSAAGLDIEVVGGDAGLVDIATDSQTDTVVAAIVGAAGLPSTLAAARAGKRILLANKEALVMAGQVMINAVKTHHATLLPLDSEHNAIFQCLPFAIQQDNTQIHRSNHGVRKLWLTASGGPFLQQSFTQMQQASVAEAVKHPNWSMGQKISVDSATMMNKGLELIEACHLFDLPENKINVVIHPQSIIHSMVEYSDGSFLAQLGSPDMKTPIAHALSYPDRIDSGSQPLDLFALNGLEFIEPDLQKFACLRLAREAMQAGTHATIILNAANEIAVSAFLNNKIRLTDIADINEQALNEIQVPLLTETADIDEILAIDNLARQYTDKLVARLA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.