PharMolix/UniProtQA huggingface dataset:
Protein: FABH_CERS1
Sequence: MTIRAVVRGVGHYLPDRVVPNSELEAIVETTDEWIRTRSGIERRHFAAEGQTTSDLAARAARAALDDAGLQPDDIDTLIVATSTADLTFPSAATMVQAALGMTRGFAFDVQAVCAGFVYALANADALIRSGQAQRVLVIGAETFSRLMDWNDRATCVLFGDGAGAVVLEGTESAGTSADRGILATDLHSDGRFKDLLYVDGGSSTGTTGHLRMQGREVFRHAVEKLAETAHTALEKAGLGAGDVDWIVPHQANLRIISATAQRMQVPMDRVILTVQDHGNTSAASIPLALSVGKARGQIKEGDLLVTEAIGGGLAWGSVVLRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERS_STRZJ
Sequence: MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_NITHX
Sequence: MTIQKNWQELIRPNKLHVVPGSDPSRFATLIAEPLERGFGQTLGNALRRILLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISIKMQGEGPKRMVVKKQGPGTVTAGDIQTVGDIVVLNPDLPICTLDDGAEIRMEFTVASGKGYVAAERNRPEDAPIGLIPVDSLYSPVRKVSYKVENTREGQILDYDKLTMMIETNGGVTPEDAVAFAARILQDQLNVFVNFEEPRKEVATEIIPDLAFNPGFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: YHJ1_SCHPO
Sequence: MPQPSYADQINVEDSSDYEKDPKEYVDKEKGYFPHVITSHISKSSSQSHPDVSNAVLDETFSFMQEAKDLEPLTPKQDKRLRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPVSKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIPAGFIAYGVQYAKNTISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTWLFTFHVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIGELAAIIIASNFGIPFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLIIRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGNHVSGFYENSMLDLTDQENLSFIYPL
What are the official names of this protein?
Uncharacterized transporter PB10D8.01.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: PLTF_PSEF5
Sequence: MKLLHERMMHSLARYPRQTAVVDEQDALSYEALELRIREFVAMLCALGVGQGQRILLWAHKSVDLVAVMQAALRLGVVYVPVDPLSPVSRLEKIAGDSQAVLVLCTAARLEELAGSALAQVRSVVLDDPASAGYWRNIDTGSSVVPTLAIQPDDLAYILYTSGSTGVPKGVALSHGNALAFVDWACERYCFQPGERFANHAPLHFDLSVLDIYCALNVGATVCLVPESIAFSPRLLTDFIRQHEISIWYSVPSVLMMMMQDGDLLSDIQDTLRVLLFAGEPFPVKHLRDLRAAYADVRLANLFGPTETNVCTAFEVGAIDPERVLPVPIGTAASGNQVWAQKPDGSRCAVGEEGELVVQGPTVMLGYFAKPAQEGPYKTGDMVRQRPDGNYEYLGRRDDMLKVRGNRIERGEVEAALLAHPQVSEAAVLVVGEGMNAQLWGVLVAHTRDALSLIDLKRHCAQRLPRYMIIDKVLCLDALPRNANGKVDRFALARQVEG
What is the function of this protein?
Involved in the biosynthesis of pyoluteorin.  Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL.
What are the official names of this protein?
L-proline--[L-prolyl-carrier protein] ligase, L-prolyl-AMP ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL17_RHILW
Sequence: MRHGKAGRKLNRTASHRKAMFANMAASLITHEQIVTTLPKAKEIRPIVEKLVTLGKRGDLHARRQAISQIRDAAVVSKLFDTIATRYATRNGGYLRIMKAGFRQGDNAAMAVVEFVDRDTFAKGAADKARVAAEEQAVAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LEU3_BRANA
Sequence: MAAALQTNIRPVKFPATLRALTKQSSPAPFRVRCAAASPGKKRYNITLLPGDGIGPEVISIAKNVLQQAGSLEGLEFSFQEMPVGGAALDLVGVPLPEETVSAAKESDAVLLGAIGGYKWDKNEKHLKPETGLLQLRAGLKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGVPRGIKTNENGEEVGYNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLDASILWRRRVTALAAEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLGALNKGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSHVQASV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, chloroplastic, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UIS2_PLABA
Sequence: MNISKFFLIFIPLVLFKYPANNELINYNVILKYDVKDLFKRVLQEQNEDIKDDNDENDEGDEEDEYYSYLKNRGTNEFDKVKYKYAEYVRFSIFKSKNIYTHIFNELLVFLGAQYGTEEEIVVHVKLIDILSLLFTHYKDNLSKFGHILNSFQDRSKLMNSVENEFMNEFINERDNYIYDVKNAYNKSDNNDDEWIETVLNKKNMLYDKFLKEWRIDGSNFYSIHNKKKTYLPKKVFQNKQNYIPDFENMEHVDLVCKPISDSAIDEKSAEKYEDKELNINEQNEQSNSKKEQTGNDNVSETKMHKEESSDSSNKTDESNVCKSENKYIKKTNNNKKIKEERHGFIYKMRNDFFLSDASLNVISLINSITSNEENKIVKKLYTGLKKLKITTFDNLIRYTNIIGIFFSYDIFDELYLQIKLIKEYFGLIPRNNDELSIVSKSKNVSKIKVYGKYNITDDEMFVPPVCLSAYCKLRSVWMQNRDFNFKIEKYSSNSINFMTLGDIGRGFKKENSYDEEQMLKLIGFNELKSTSNAMKDWHASNNADFVINLGDNVPEVDELDYLKNFEWHKIMRELFTFRKQDEDEEKNDADSYSITKDNIQEFYKEVEKQMNNTNTDDKNQHNDISTTPINNYTDGNEGNNNSENNNGFREYINDNTKDYNIYKNETTEKEETYDSIPFFSIFGEKDYFYFPSEQIQEHYAKRIPGYFFPNNYYRINYDFVYNNKEKNGVQEKFKASFIFIDTWSLMIGFPIIRNYRSFREQFNWINKALLESAKESDWIFVVGHHPFISSGRRSDNYSFEELSFHNIIRNFFFYYNIDGYFSAHDNLMEYLNFGPLNLFVNGSSSRVLFDKSTILGRGYFGKMVGSIYPVTCYLLTTIHSALRPKGCDISKYSKWSNKYDIGFSAHKLSKDELVTEFINSRSGKPVSQKIVIKNKKDKRRKFYDLDGYTNDKIKQFENKIYEFSSKNPNFIKYKIEEFKENDKKLNIIMNNLKSEEEKDAFRSLMFLNNLIFGISSHISNISFDQLKLMCYLANKYRTFFNKKLIKFLGEELKIAVQKMEVKTTNETPHNSNEILNTNENESIQPNDPTMKVEQIMELIDTLGYKPDEFLEKYDAMTQEEKDALKEKLGNDVSLEDYLSKVKMYIHKKKLSAEELKEYEENEENIKIAEVPDESKEDDNTNSQPEDTIDQENKDDINDIINAPNEVHKNYKELVEKEKKLTENEHALLMLSSLKTYDEMKYSLNILSKKEVIKEEAHPYGLYYIEKHKTFFQVSLELCPDIKRIISNLGKVGTKLAFYDYINNLYNKIMDLKNSIDKIAIF
What is the function of this protein?
Protein phosphatase which dephosphorylates 'Ser-59' of translation factor eIF2alpha during the liver stage, thus enabling protein translation.
What are the official names of this protein?
Serine/threonine-protein phosphatase UIS2, Up-regulated in infective sporozoite protein 2.
Protein: COAX_CLOPE
Sequence: MILLIDVGNTNIVLGIHDNEKYIASWRISTDSKKTSDEYSIQVMQLFNQAKLNPEDVEGIIISSVVPNIMHSLENMVRKCFCKEPIVVGPGIKTGINIKYDNPKEVGADRIVNAVAAFEKHKKPMIIIDFGTATTFCAITEKGDYLGGNICPGIQISADALFERAAKLPRIELEKPKSVICKNTVTSMQAGIIYGYIGKVEYIVKRMKKEMMDLGEKEPFVLATGGLAKLVYSETDVIDEVDRKLTLEGLKILYEKNKE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y266_LISIN
Sequence: MLTWVIRVCFLILGGTTGVFSLPALWVKLGIGHILLINNPYTDALIGALIFYLITFWAVKYVEAALNWLEEKLAKIAIATLIYGGLGLFVGLVIAFFASNALSQTNIPLLNSVVPVILTLVLGYLGFRIGISRRNEFGNFVNNRNAKKKTPEEEQTEEKSKKTYKILDTSVIIDGRIADILATGFLDGTVVIPLFVLAELQHIADSSDTLKRTRGRRGLDILNRIQKEDSIQVEMYEGDFEDTPEVDSKLVKLAKVMGGIVVTNDYNLNKVCEFQNVPVLNINDLANAVKPVVLPGEKMTVLMVKDGKEHNQGVAYLDDGTMIVVEDGRKFINETIQVEVTSVLQTSAGRMIFAKPS
What is the function of this protein?
An RNase.
What are the official names of this protein?
Uncharacterized PIN and TRAM-domain containing protein Lin0266, Putative RNase Lin0266.
What is the protein family that this protein belongs to?
In the central section; belongs to the PINc/VapC protein family.
Protein: TANA_ARATH
Sequence: MVARTPQKQRKVAMVVPPLNSDLLKETINKVDKCMERLQELQYTIAGGTKVVSGVNLSPRSTRIYLKTSLRCKQETLRIKNATNKKSPVGKFPASSPGDWRKMSLPAMLLGETVNEILQASQVTRDIVDAIAPKKSRKSRRLTMSQEDDGPKTPETQQKSREQNPETVSSNIKARRKKEKQNRRSESDSPPSLQRARSRIAFRTISPQVKGNNGENSFRHLANRVSPKHKPWVKKAVLFPNPLFISGTATQQAKFSRTMSPVIARNEISSIKNNKETPYKFLIKSPPTSASKFQVKIRSPPKVLVSPTRNGSNSVRKSPRGSRSPTRTVNLGKKSASISPIRNTGKRSPKLSTAAKLRRSFTPTRNGSNLARKSSISPKRVTLQAFLSPTRNGNFCKKSPKASISPTRVCNKSQKLSTAAKFRRSFSPSRLAMRFVSPMKSRKSVAKCDDHEMVSGLKQRPVLVPKRFSIRRI
What is the function of this protein?
Is required for spatial control cell division during plant development.  Through an association with microtubules, acts both for the positioning of cytoskeletal arrays that establish planes of cell division during prophase and for spatial guidance of expanding phragmoplasts toward preestablished cortical division sites (CDS) during cytokinesis.
What are the official names of this protein?
Microtubule-binding protein TANGLED, AtTAN.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Cytoplasm, cytoskeleton, phragmoplast. Note=Preferentially localized to the preprophase band (PPB) during early stage of mitotis and later localized to the cortical division sites (CDS) during cytokinesis.
Protein: GLMU_KLEP3
Sequence: MSNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGDLLRQTLHEDNLNWVLQAEQLGTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAAKPLGGIGLLTVKLDNPTGYGRITRENDQVTGIVEHKDASEAQRQIQEINTGILIAGGADLKRWLAKLTNNNAQGEYYITDIIAMAYQEGREIVAVHPQRLSEVEGVNNRLQLARLERVYQAEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKNSTIGDDCEISPYSVVEDAQLQAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDVFVGSDTQLVAPVTVGNGVTIAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_MANSM
Sequence: MTNFTVIIPARFASSRLPGKPLADIAGKPMIIHVLEKARLSGATRVVVATDNEEVKQAVEQFGGEVCMTSAKHNSGTERLAEVVETLNIPDDEIIVNIQGDEPLIPPVIVSQVAENLCKFKVNMASLAVKIHESAELFNPNAVKVLTDKDGYVLYFSRAPIPWNRDAFARLNSGELKQEELDLADHYLRHIGIYAYRAGFIKQYVQWEPSALEQIESLEQLRVLWYGEKIHVELAKEIPAVGVDTAEDLEKVRAILSNF
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT3_RAT
Sequence: MSGDYEDDLCRRALILVSDLCARIRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHAHPAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRTGGGSGEAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGLLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLSSFTKGGKGLSEKENSE
What is the function of this protein?
Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain.  Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (PubMed:11823420, PubMed:18508778).  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Synaptotagmin-3, Synaptotagmin III, SytIII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.
Protein: NU2M_PTEPU
Sequence: MNPLVFTVIMSTVMLGTAIVATSSHWLMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAVTMNLVYSGQWSVTKPLSPTASTIMTLAMAMKLGLSPFHFWVPEVAQGISLPSGLILLTWQKLAPMSILYQISSTINLDLLMTLSILSIGIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILAYNPTMTLLNLAIYILLTTTTFMMFMLSSTTTTLSLSHTWNKMPLLTTAILLTMLSLGGLPPLSGFMPKWMIIQELTKNDNVILPTMMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKMKWQFNYAKSTTHLSPLIILSTLILPLSPMLALLE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YL781_MIMIV
Sequence: MVCGDANTMKCENFYPICPREMSIVIEIINENCDYHTTTENCQDKIFTVLDKNRRPTMYHECDDIIYVYDRVTGIIIDFKNIKSAKKYKLCHNRYSESGRVIMKEMEKLQSRGWTCLNEPCRNPWCVLAPKELADVYAEINAENNAENKPN
What are the official names of this protein?
Uncharacterized protein L781.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R69 family.
Protein: ILVC_GEOTN
Sequence: MAKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDGFDVYSVREASKKADIVMVLLPDEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPEHVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHAKETALAYAKAIGAARAGVLETTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYEGGLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPEFNAINQRENEHLIEVVGRELRSMMPFVKAKQKEVVVPGAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NDUC1_BOVIN
Sequence: MAPSALLRPFWKLLAPARFPSVSSSRSKFYIQEPPHGSPNWLKVGLTLGTSVFLWIYLIKQHNEDVLEYKRRNGLE
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial, Complex I-KFYI, CI-KFYI, NADH-ubiquinone oxidoreductase KFYI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: CYC6_CHACT
Sequence: GVIPCGESCVFIPCISSVIGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Chassatide C6, Cyclotide chaC6.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: PSBT_PROMM
Sequence: MDAFAYTLLMTLVVATLFFAVAFRDPPKIGKDSGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DUT_CANAL
Sequence: MTSEDQSLKKQKLESTQSLKVYLRSPKGKVPTKGSALAAGYDLYSAEAATIPAHGQGLVSTDISIIVPIGTYGRVAPRSGLAVKHGISTGAGVIDADYRGEVKVVLFNHSEKDFEIKEGDRIAQLVLEQIVNADIKEISLEELDNTERGEGGFGSTGKN
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: U119B_MOUSE
Sequence: MSGSNPKAATAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTPDDGSGAAVTEQELLALDTIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQDAEEESVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLVMHNKADYAYNGGQ
What is the function of this protein?
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane.  Does not bind all myristoylated proteins.  Probably plays a role in trafficking proteins in photoreceptor cells (By similarity).
What are the official names of this protein?
Protein unc-119 homolog B.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Enriched at the transition zone and extended into the proximal end of the cilium.
Protein: Y182_SYNJB
Sequence: MKIAYFDCAAGIAGDMCLGALLDCGVPLEYLNRQLQALGIEGEYGLQVSRVQRCGQPALQAVVEVLGSQSGGSLARHWAEIQALIAGSQLSPAIKARSLAVFEKLAQAEAKVHQMPVEEVHFHEVGAVDALVDIVGTCIGLDWLQVERVLSSPHPVGGGWVSTEHGKLAVPVPAVIELWEMGRVPVFSNGVEAELVTPTGAALAVALAEEFGPCPPMRVEKVGRGAGAQELPIPNVFRLWIGEANGGELTETVSVLQTQIDDLNPQVIAYTCEQLLALGAWDVFTQPITMKQGRPGILLTVICPPDRVPECQDLIFRETTTLGIRHFQQQRTLLERVVERVETPYGLVDIKVARHHGRIVNAQPEFRDCVARAQEFHVPVQTVWLAAQSAWQNRLQG
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: BLAR_BACLI
Sequence: MSSSFFIPFLVSQILLSLFFSIIILIKKLLRTQITVGTHYYISVISLLALIAPFIPFHFLKSHHFDWILNLGGAQSALSQTHSTDKTTEAIGQHVNWVQDFSLSIEQSSSKMIDSAFFAVWILGVAVMLLATLYSNLKIGKIKKNLQIVNNKELLSLFHTCKEEIRFHQKVILSRSPLIKSPITFGVIRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLLKIVYWFNPLVWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSIKQRTSSLLAASEFSSSYKHIKRRIVTVVNFQTASPLLKAKSALVFTLVLGAILAGTPSVSILAMQKETRFLPGTNVEYEDYSTFFDKFSASGGFVLFNSNRKKYTIYNRKESTSRFAPASTYKVFSALLALESGIITKNDSHMTWDGTQYPYKEWNQDQDLFSAMSSSTTWYFQKLDRQIGEDHLRHYLKSIHYGNEDFSVPADYWLDGSLQISPLEQVNILKKFYDNEFDFKQSNIETVKDSIRLEESNGRVLSGKTGTSVINGELHAGWFIGYVETADNTFFFAVHIQGEKRAAGSSAAEIALSILDKKGIYPSVSR
What is the function of this protein?
Integral membrane protein involved in sensing of the presence of beta-lactam antibiotics and transduction of the information to the cytoplasm.  Mechanistically, activation of the signal transducer involves acylation of a serine in the C-terminal sensor domain upon binding of the beta-lactam antibiotic.  In turn, a conformational change occurs and the signal is transmitted from the cell surface to the cytoplasm.  There, the zinc protease domain is activated and initiates autoproteolysis as well as cleavage of the transcriptional repressor BlaI leading to derepression of antibiotic resistance genes.
What are the official names of this protein?
Regulatory protein BlaR1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M56 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FIXB_CLOSA
Sequence: MNIADYKGVWVFAEQREGELQKVSLELLGEGRRVADKLGVKLTALLLGSNVEGIKDLAEHGADEVLVADNKDLQHYTTDAYTKVICDLANERKPGILFVGATFIGRDLGPRVAARLNTGLTADCTSIDVEVENGDLLATRPAFGGNLMATIACPEHRPQMATVRPGVFEKVNTDGANCKVEKVEVKLTNNDLRTKVLEIIKSKKDIVDISEAKIIVAGGRGVGSKENFELLGELAKVLGGTVAGSRAAVEKGWIENAYQVGQTGKTVKPSIYIACGISGAIQHVAGMQDSDMIIAINKDETAPIMKVADYGIVGDVKNVLPELIAQAKEIISAE
What is the function of this protein?
May play a role in a redox process.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: CH10_PSEPK
Sequence: MKLRPLHDRVVIRRSEEESKTAGGIVLPGSAAEKPNRGEVVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDGEDLLVMAENEILAVVEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7609_DICDI
Sequence: MDLSDLVQLYSDGIPQPTITPPTQNKDELNKNNNNKNKIIRHKGGNKNNRNNKNNVDNNNNNNNNNNNNEKQNQTNVNNEKITNTETLEIKKNNNNNNNNNNNNNNNNNNNNNNKNKYNKFNDNNNKKNKRNNDDDDDKEEMKRIKLFNQRLKEIKIQESPEDIARYLEERRRRYPSKANIEAKKKEEEDARKRGELLYNNNNNSKKKQTPDKKKKLENQTSKNNNKSSTTKTELTNTTTNTSSTTNPTTDTTTTTTNVVSIQKENENQEKENNDNDNDNEPIEVPSTLEFNKFEEKPIKEVKVNTASSNKRNKKRNNPKKVKEEPQVNKFQDSLFTKLFERDISAENNIILQCFRHFANKINQINGNDKLDEKKEI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0274405.