PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_ECO55
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: THNS2_RAT
Sequence: MWYTSTRGMAPRVNFEGALFSGYAPDGGLYMPEELPRLDKETLRHWSTLSYRSLVKELCALFVGLELIPRHDLNGLIDQAFSRFRHRDVVHLCKLKNGLNILELWHGVTYAFKDLSLSCTAQFLQYFLEKKKKHVTIVVGTSGDTGSAAIESVQGSKNVDIIVLLPKGHCSKIQELQMTTVVKENVHVFGVEGNSDELDEPIKAVFADVAFVQRHNLMSLNSINWSRVLVQMAHHFFAYFQCTPSLDMHLLPTVEVVVPTGAGGNLAAGCIAQKMGLPISLVVAVNRNDIIHRTVQKGDFSLCEVVRKTLASAMDIQVPYNMERIFWLLAGSDSQTTRALMEQFERTQSLHLPKDLHSKLSEAVTSESVSDEAITQTMGRCWEENQYLLCPHSATAVSYHYQQTDSGQPSSIPRCCLAPASAVKFPEAVQAAGLTPETPAEILALEHKETRCTPMRRGDDWTQMLRDTIEALSLRWKGCVENTAE
What is the function of this protein?
Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates.  Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).
What are the official names of this protein?
Threonine synthase-like 2, TSH2.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: TSAD_THEAB
Sequence: MIVLGIETSCDETSVAILSDGKILSNVVSSQIDIHKKFGGVVPEIAARHHLSNLPIVFKNAIDMANISIDQIDLISVTYGPGLIGALLVGISFAKGLSLRLGKPLIGVNHIVGHVFANYITYPHLKPPYIVLMVSGGHTEILLVKQDDEIEVLGKTVDDAAGEAFDKVARILGLGYPGGPEIDKLSKNGDENKFNFPRPMMDSKSYNFSFSGLKTAVLYTVQKFDKDNVPKEDIAASFQKAVVEILLKKTFKAAKDLNVNTIVLAGGVAANSYLRKKAQKLSEKQNIKVLIPPLEFCTDNAAMIAMAGYKLYKKGISSDSTLEAVPNLKI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUK_CLOBB
Sequence: MSYKLLIINPGSTSTKIGVYENEKELFEETLRHTNEEIKRYETIYDQFQFRKDVILNILKEKNFDITTLSAIVGRGGMLKPVEGGTYAVNDAMIEDLKVGVQGPHASNLGGIIAKSIGDELNIPSFIVDPVVTDELDDVARLSGVPELPRKSKFHALNQKAVAKRYGKDSGKGYENLNLIVVHMGGGVSVGAHKQGKVVDVNNALDGDGPFSPERAGTVPVGDLIKMCFSGQYTESEVYTKVVGKGGFVGYLNTNDVKGVIDNMEAGDKDCEKIYKAFLYQITKTIGEMAAALNGKVDQILLTGGIAYSPTLVPDLKSNVEWIAPVTVYPGEDELLALAQGAIRVLDGEEKAKIY
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQBO_BACSU
Sequence: MAKLTATFELHDKISRKLRMIQGNAERLKRAANGPLIFEAEDRTERVMRQIDRSANRLTARARLLEMGLDDRVSNGLHSIRQQAEDLTEGSHEVTVSVNDQATPRFRLIRGGLTDLNSSHAEPTVSVRDHASNQLDEIRRHVTDVDSEHAEPTVSIKDRASAALDAIEAKIDSLKGATITLAVAGGFSAGSIMGSGKSTMSQDAYVSATSNVNKKDVAKMTDQIYFNNKAGSSREEVSLSLRNLSQQTGASKKALAELTESSSKIAQLMNADQAEVDRAFSSMYNNLKLSGKQSGDLIAYVYRNAGDQADDLLDTMNEYSSTFKDLKLTGGQIANAMIKGTKGGARNFDNLADSMREFNIRRTEMSDSQVDAFKTLFGAKETKKMFKGFKDGSISGEESLFRVAKALSKVKDKTKRAAIATELIGTQYEDLKQPILDMAEGIGTSAKTSGELERSFTKLRDNNPMTPVNDAMRDFESISKDMGTSLLTGLGPAFDKISSFINSKEGQEKLKEIKKDIADLGEEIGDKLNVAIEWSVNHWDDLKTAIKVVIPSLIGLIGYLKILRPLLKGIGTVGSDAAGVIRKLIPKRTPKAGTNTQSERRNRNSNRNASTRGRESKTATGPTSLPRSGSLTYCCCSDGGKNDRIRRRRGKRVLGRRGNPNRMNPSDSSIAVSSERLERRRSGRTVGTNPTRDSRSAIITTRSELYSAGRAAGGTSKFGKVLSPLKSVGKFAKGVPLLGTALAATDLIGMNKDNVGEKIGSAGGGLAGAATGAAIGSVIPGVGTAIGGLVGGIAGTMGGSSLGKAFDGSEVKKKLNSTLFDQKWWSEKWSGIKSNAKTSINGLSDTWSNVKEKVKSTLFNSEWWSEKWSGVKSWAQNKWNSASSVWESVKGKIKSTLFSEKWWSGKWEGVKSWAQSKWDSASSVWQSVKGKLKSTLFSEKWWSGKWESVKSWSKNKWDNAKSIWKSVKSSISETLFSKKWWSEKWQSVKELGSSILGGVKEVGGKVASSAKKTAGKAWGYVKSGVNYLFGSGKEKPKKHATGGYITKPTISWIGEAGKEFVIPVENNKGRGKMLLSQAASKLGMSVVDDIASASSAGGEPATSPLVRSAAVTASVSPIIDTSSLDEQATSFGQQFTKSFDQGIRDNVVSMEAWKQKNVGQPMNNLISYSPNYGKQVVNGYAKGQNSTSTGTDGFLQTKVKMPFQNTVNKSSSWGSGTIKGFASGQNSSQTGTDQYVSTHINKPFIRSKESSNGWGSGMIGNFVSGMTSKASEVNEAAKELAKKVEKAFREELDIHSPSRVMMSLGRFASIGIVKGLDSVDVKKFAEKQAGSLAAAYSGMGAVSGNVKQWLMAAIMATKTPMSWLPGLMTIAQHESGGNPKAINLWDSNAKAGHPSQGLMQTIPSTFNAHKLPGMNNILNPIHNAAAAIGYIKSRYGSINNVPGIRSMRHGGPYVGYANGGLITKEQIARVGEGNKREWIIPEERGIRGRYLLAQAAKALGMEVTDPSEKGQTELSSGQVTAATTGRNQTTFKAAGGKEVIIQFNGDQHFHNDQDMNSLVAKIKQALVDELEQDINIGTKGVVAFD
What are the official names of this protein?
Uncharacterized protein YqbO.
What is the protein family that this protein belongs to?
To B.subtilis XkdO.
Protein: RF3_XYLFT
Sequence: MSEVVAETARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKSRKAVRHATSDWMTLEKERGISVTSSVMQFPYEGKIINLLDTPGHADFGEDTYRVLTAVDSALMVIDVAKGVEERTIKLMEVCRLRDTPIMTFINKLDREGKNPIELLDEVERVLGIQCAPVTWPIGMGKRLRGVVNLLTNEVHLYEPGRNFTRQDSIIFTSLEAPGLAERIGEQMLADLHEELELIQGASACFDPTEYLGGRQTPVFFGSGVNNFGVQPLLDFFVEHAPSPQQRDTTSRVVLPTEEKLTGFVFKIQANMDPQHRDRVAFMRVCSGRFTAGMKAFHVRSSKDLKLANALTFMASDRESVAEAFPGDVIGIHNHGRVSIGDTFTEGEVLSFTGIPSFAPELFRRACLGDPLKLKQLQKGLTQLSEEGATQFFRPLMSNDLILGAVGMLQFDVVAYRLKNEYGVDATFEPVSITTARWVYCDNSKTLEEFREKNVTNLAVDASGELVYLAPTRVNLQLAQERAPEIHFFATREHAYAVGVD
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STRP3
Sequence: MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIKVEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RECO_ECOK1
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: C7A27_EUPLT
Sequence: MDLQLQIPSYPIIFSFFIFIFMLIKIWKKQTQTSIFPPGPFKFPIVGNIPQLATGGTLPHHRLRDLAKIYGPIMTIQLGQVKSVVISSPETAKEVLKTQDIQFADRPLLLAGEMVLYNRKDILYGTYGDQWRQMRKICTLELLSAKRIQSFKSVREKEVESFIKTLRSKSGIPVNLTNAVFELTNTIMMITTIGQKCKNQEAVMSVIDRVSEAAAGFSVADVFPSLKFLHYLSGEKTKLQKLHKETDQILEEIISEHKANAKVGAQADNLLDVLLDLQKNGNLQVPLTNDNIKAATLEMFGAGSDTSSKTTDWAMAQMMRKPTTMKKAQEEVRRVFGENGKVEESRIQELKYLKLVVKETLRLHPAVALIPRECREKTKIDGFDIYPKTKILVNPWAIGRDPKVWNEPESFNPERFQDSPIDYKGTNFELIPFGAGKRICPGMTLGITNLELFLANLLYHFDWKFPDGITSENLDMTEAIGGAIKRKLDLELISIPYTSS
What is the function of this protein?
Involved in the biosynthesis of macrocyclic lathyrane type diterpenoids (also called Euphorbia factors) natural products, including the cyclization route from casbene to jolkinol C, a precursor for ingenol mebutate that is used to treat actinic keratosis, a precancerous skin condition (PubMed:27506796).  Catalyzes the hydroxylation of (-)-casbene and 8-hydroxycasbene to produce 4-hydroxycasbene and 4,8-dihydroxycasbene, respectively (PubMed:27506796).
What are the official names of this protein?
Cytochrome P450 726A27, ElCYP726A27, 4,5,8-trihydroxycasbene synthase, 4,8-dihydroxycasbene synthase, 4-hydroxycasbene synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DNLJ_SYNAS
Sequence: MMDAESARKNIEDLKARIEYHNRRYYQLDDPEISDAEYDSLLQELIALEKQFPQWLTEDSPSRRIGAAPLSKFAPAVHLSPMLSLANAFSEEEILEFDRRLKRFLDSSERLSFVVEPKIDGVAVNLIYSSGVLTTGATRGDGAKGEDVTQNIRTLHTIPLKIQNGSDERLPEQIEIRGEIYMETAAFRKLNERRLAAGEPPFANPRNAAAGSLRQLDASITARRPLKMFCYAVGIVRGRAFTYHHDVLHALKKWGFSVNPFIRQVEGIEKCIEFYRELQDLRNELPYEIDGMVIKVDDLSLQTRLGAVSRSPRWAVACKFAATQATTVIRDIIVNVGRTGTLTPVALMTPVKVGGVTVSRATLHNQDEIDKKDIRIGDTVLVQRAGDVIPEVVKVIVSNRSGREIPFKIPDTCPECGSEVVRLAGEAAHRCIGLSCPAQLRRHIQHFVSRGGMDIEGLGDKLVSQLVNQKLIHDPADLYYLSHDALLNLERMAEKSVSNLLSAIELSKHPSLDKIIFALGIRHVGEHISKILARRFRTLDALINTTENELLAIRDIGPEVSSSILEFFRNASNRRVIEKLKKAGVSPLETISPRSAPLTGKTFVFTGALSRMTRDEAKQIVESLGGQAAGTVTKKTDYVVAGEAAGSKLQKAQKAGIAILSEEEFLRLAGKI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: O165_CONLT
Sequence: MKLTCVPIVAMLFLMACQLITADYSREKHGYSAEKSSDKIQDSFYSKLTKGCTDEGGDCDPGNHNCCRGSCLVLQHKAVCGILYTMVSR
What are the official names of this protein?
Conotoxin Lt6.5, Lt6e.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE_PSESM
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGIEWSEGPDVGGPHGPYRQSERGDIYQKYAQQLVELGHAFPCFCTAEELDEMRAEQQAKGETPRYDGRALLLSKEEVQRRLDAGEPHVIRMKVPTEGVCVVPDMLRGEVEIPWDRMDMQVLMKTDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLILLYEYFGWDKPQLCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLQEMVDHFDLSRVSLGGPIFDIEKLSWLNGQWLRELPVEEFASRLQTWALNPEYMMKIAPHVQGRVETFSQVAPLAGFFFAGGVTPDVKLFEHKKLSPDQVRQVMQLILWKLESLRQWEKERIMGSIQAVVEHLELKLRDAMPLMFAAITGQANSVSVTDAMEILGPDLTRFRLRQALDLLGGVSKKENKEWEKLLGAIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5086_AFIC5
Sequence: MATAAAAKEDVAHRFAKDQLKAIIERIERLEEEKKTISDDIRDVYAEAKGNGFDVKALRTIVRMRKQDANEREEQETILETYMQALGML
What are the official names of this protein?
UPF0335 protein OCAR_5086/OCA5_c28780.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: RSMC_SHIFL
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSCQMGDNARFSLVATANDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGCFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BACHK
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP20_TOBAC
Sequence: GPEEWVK
What are the official names of this protein?
46 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: KDPA_SALG2
Sequence: MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGVERILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLALNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNVHTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGDRRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKETRFGVLASSLFAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMA_AGRVS
Sequence: MAALDGLPPLRDVIQRHGLDAKKALGQNFLLDLNITQKVARTAGDLTNATVFEVGPGPGGLTRALLALGAKKVIAIERDSRCLPALAEISDHYPGRLEVIEGDALKTDFEAMAPDGPVKIVANLPYNVGTQLLINWLMPRQWPPFWDSLTLMFQKEVGQRIVAEADDDHYGRLGVLCGWRTEAHMAFDLSPQAFTPPPKVTSTVVHLTPRPAPIPCEIAKLEKLTQAAFGQRRKMLRASLKPLGGEALLNRAEIDPSRRAETLSVEEFCRIANLL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_THEP3
Sequence: MAAIKYRLIKKDSRTNARLGILETPHGIIETPVFMPVGTQATVKSMTPEELKEIGATIILSNTYHLYLRPGHKIIEKAGGLHKFMNWDRAILTDSGGFQVFSLNSLRKITEDGVEFRSHIDGSRHFFTPEKVIEIQNALGSDIMMSFDECAPYPADYDYVKKSMELTIKWAERGKRAHKNTEKQALFGIVQGGTYEDLRKECAQRLVDMDFPGYSIGGLSVGEPKNVMYDIVDLTTEYLPEDKPRYLMGVGSPDDLIEGVIRGVDMFDCVLPTRIARNGTVFTSKGKLIVRDAPYAEDFSPLDEECDCYTCRNYSRAYIRHLFKANEILAARLATIHNLYFLIKLMERIREAIRQDRLLEFKKQFFKKYGYKEEY
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TRUB_THEVB
Sequence: MFGFLNLNKPAGCTSHDCINELRRRLRLKRIGHGGTLDPMATGVLPIALGAATRLLPYLSDRKAYIGTVRFGMSTTTDDITGEICQEQGASHLTLAAIQEQLPQFIGEIEQLPPAYSAIQVAGQRLYARARAGEVVSVPPRIVTVYRIEVLHWQPGRYPELTLHITCGSGTYIRALARDLGTALGVGGTLAALQRIESGGLRIEESHSLESIAPEHLPLCSPQEVLSHLPWLELNAAQLNDWYHGRAVICEGLPPADSCVGVTFATACVGVGISGGDRLHPKVVLKE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RL19_STAHJ
Sequence: MSNHKLIEAVTKSQLRTDLPTFRTGDTLRVHVRIVEGSRERIQVFEGVVIKRRGGGISETFTVRKISSGVGVERTFPLHTPKIEKIELKRRGKVRRAKLYYLRSLRGKAARIQEIR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NRP1_HUMAN
Sequence: MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLVDECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGDKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQSTYSEA
What is the function of this protein?
Binds VEGF-165 and may inhibit its binding to cells (PubMed:10748121, PubMed:26503042).  May induce apoptosis by sequestering VEGF-165 (PubMed:10748121).  May bind as well various members of the semaphorin family.  Its expression has an averse effect on blood vessel number and integrity.
What are the official names of this protein?
Neuropilin-1, Vascular endothelial cell growth factor 165 receptor.
What is the protein family that this protein belongs to?
Belongs to the neuropilin family.
What are the subcellular locations of this protein?
[Isoform 2]: Secreted. SUBCELLULAR LOCATION: Mitochondrion membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: RMAR_SCHPO
Sequence: MQKNNLKNLITTIVTNAFFNQKANFSIPLKGVIGEKRPSILIGNININFKSDSLIEVSFPYYPLLNKNYPNPSIISNIIQKALSNHLLYSSKNYSFIVNIRALPISTPYGSSLIFSKYIAIIIGSNPKIASTLWIDPKRFINLPKLQSDSIFKILGLNVPKGWKGIHISLNLIKWNSLSSRGRITNIIKGSVPLTNNSNGYDESSLAIYSKMGTIQIKVRLSYSSNL
What is the function of this protein?
Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
What are the official names of this protein?
Ribosomal protein var1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYGA_ACISJ
Sequence: MLTFQQIILKLQSYWADQGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQYQVVLKPAPDNILELYLGSLEALGFDLKKNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPATGEITYGLERLAMYLQGVDNVYNLTWTEGPNGAKLTYGDVYHQNEVEQSTYNFEHSDAEFLFTAFGAHEKQANHLMGEQLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLARAVAKAYLDSRARLGFPMAPKAHADEVLAELAKAAEQQNKKAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_SALCH
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H2A04_CYRHA
Sequence: MKMTLIAILTCAAVLVLHITAAEELEAESQLMEVGMPDTELEAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.4, HNTX-II.4, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GP55_BPSP1
Sequence: MFKLLTLFKRNKITSAEEYYTQAIHICEQFDRSTQKYTSM
What are the official names of this protein?
Putative gene 55 protein.
Protein: YIBT_SALPA
Sequence: MAKIGENVPLLIDKAVDFMASSQAFREYLNKTPPRDYVPSEVPSESAPIYLQRLEYYRRLYRPKEEERG
What are the official names of this protein?
Uncharacterized protein YibT.