PharMolix/UniProtQA huggingface dataset:
Protein: RL19_LACJO
Sequence: MDPLIQELTKEQLRDDMPDFRAGDTVRVHVRVVEGTHERIQMFEGVVIKRKGAGISATYTVRKMSSGIGVERTFPVNDPRVAKVEVLRHGRVRRAKLYYLRERHGKAARIAEKRRG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL20_STAEQ
Sequence: MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHDISYSRLMNGLKKAEIDINRKMLSEIAISDDKAFAELVSKAKEALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RUVB_PARUW
Sequence: MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSGPPGLGKTTLASILSKAMESNLVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSVEEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATTRLGLLSEPLRSRFAFTCRLEYYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYIDLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYEPYLILQGLLKRTPRGREVTSLGYQHIVGSSQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SYGA_NEIMB
Sequence: MLTFQQIIFKLQTFWADKGCTVIQPFDMEVGAGTSHPATCLRALGPEPWFAAYVQPSRRPKDGRYGDNPNRLQHYYQFQVALKPAPANIQDLYLDSLRELGIDPKVHDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCTPVLGEITYGIERLAMYLQGVENVYDLVWAKTLDGNTVTYGDVYHQNEVEQSTYNFEYSDADWLLRQFNDYEAQAKRLLAEENAALALPAYELVLKAGHTFNLLDARGAISVTERATYIGRIRALSRAVAQKYVESREKLGFPLMKANAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SYNJB
Sequence: MAKKSMIEREKKRQRLVEKYREKRQQLKAAMADPNIDQATRMELHAQLQKLPRASSPTRLRNRCWKTGRPRGYFRDFGLCRNSLREMAHRGLLPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: COXX_METSB
Sequence: MSFVSDSNTAIDQAAISIASPADYLALMKPRVMSLVIFTALTGVLIAPTHVNPIIGFASLLAIAAGAGASGALNMWYDSDIDAIMRRTQKRPIPAGRVARESALAFGMVLALLSVITLGFVANWAAAALLAFTIFFYVVIYTMWLKRSTPQNIVIGGAAGAFPPIVAYLAVAGQVSLPALALFAIIFVWTPPHFWALALVKAGDFERAGIPMLPNVKGPDRTRRDILLYTLLLAPIGMTPYFIGFASPAYGLLSFGLGGVMILHAVRVYLAREGDQANRVAMRMFGFSILYLFLLFAAIVAERILALLPISSATPW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_ECOUT
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_PROM2
Sequence: MNNIRTIKGGTKLKGKIKVPGDKSISHRALIIGSIAKGNTTIEGFLHSEDPLSTADCLRKLGVNIPKIIKDEPFTISGKGLDGLKEPKEILNCGNSGTTMRLLMGLLAAQEGKNFILTGDASLNERPMGRVGKPLSLMGGKISGREFGNKAPISINGEKLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADISIRGELGRNIVITSGGNLIGQRILIPGDISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKTSNNLRSFTVEGDILPKLIDEIPILTVAACFCSGVSEIKDAQELRVKETDRLKVMARQLQKFGAKITEKEDGLIINGQSKFHSAEVDSETDHRVAMSLAIASLLAKGTSKIMRAGAASVSYPTFWEELDKLTN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCLE_BACSU
Sequence: MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQKYQWVFVDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMALEYARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIENLPQDIDKDPERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIIDELWGNTFARIDLLQRLADVRMPVYIGLGRYDYLVAPVSLWDAVDGLYPHVDKVIFEKSGHQPMLEEPEAFDQSFRKWLDQ
What are the official names of this protein?
AB hydrolase superfamily protein YclE.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: SECA_SHEPW
Sequence: MFGKLLTKVFGSRNDRTLKAFGKVVNKINGFEEEYGQLSDEELKAKTKVFRERLEAGETLDDVLPEAFATVREASKRVFEMRHFDVQLIGGMILDSNRIAEMRTGEGKTLTATLPAYLNGLTGKGVHVITVNDYLAGRDAENNRPLFEFLGLSVGINVAGLGQVEKKAAYDADITYGTNNEFGFDYLRDNMAFSPAERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYTKINTLIPNLIQQEKEDTEEEIGEGDYSIDEKAKQVHMTERGQEKVEVLLTERGMLAEGDSLYSAANISLLHHVNAALRAHTLFEKDVDYIVQDNEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVHIQNENQTLASITFQNFFRQYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRQDNPDLVYLTAEEKYAAIVKDIVGCRERGQPVLVGTVSIEQSELLHSLLKKEKIPHEILNAKFHEREADIVAQAGRTGAVTVATNMAGRGTDIVLGGNWNMEIEALANPTDEQRAKIKADWQIRHDEVVDAGGLHILGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLMRIFASDRVSSMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVYAQRNELMDAESIKDTITNIQTDVINELMDQYIPPQSVEELWDVAGLEQRLQQEYTMVLPIQEWLDKEDDLHEETLRERIVDTWINAYKAKEEMVGEQVLRQFEKAVMLQTLDGLWKEHLSAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQMLESLKHDVISILSKVQVQAQSDVEEMEERRRQEDAKIRRDYQHAAAEAIVGAEESAALAATQPQVREGEKVGRNDPCPCGSGKKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SACT_BACSU
Sequence: MKIYKVLNNNAALIKEDDQEKIVMGPGIAFQKKKNDLIPMNKVEKIFVVRDENEKFKQILQTLPEEHIEIAEDIISYAEGELAAPLSDHIHIALSDHLSFAIERIQNGLLVQNKLLHEIKALYKKEYEIGLWAIGHVKETLGVSLPEDEAGYIALHIHTAKMDAESMYSALKHTTMIKEMIEKIKQYFNRKVDENSISYQRLVTHLRYAVSRLESNEALHRMDEEMLYFIQKKYSFAYQCALELAEFLKNEYQLHLPESEAGYITLHVQRLQDLSE
What is the function of this protein?
Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription.
What are the official names of this protein?
SacPA operon antiterminator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family.
Protein: MTAD_THEON
Sequence: MSILIKNGYVVYGENLEVIKADVLIESNKIVEVAKNINKSADTVIDAKGKVVSPGFVNLHTHSPMGLFRGLADDLPLMDWLQDHIWPKEAKLTREYTKVGAYLGALEMIKSGTTTFLDMYFFMDAVAEVTLESGLRGYLSYGMIDLGDPEKTEKEVNEALRIMKFIEGLDSDRVHFVFGPHAPYTCSIALLKEVRRLANEHGKLITIHVSETMAEIGQISERYGKSPVVLLDDIGFFGRDVIIAHGVWLDSRDIQILARHGVTVAHNPASNMKLASGVMPLQRLLNAGVNVGLGTDGSASNNNLDMLDEMKLAALLHKVHNLDPTVADAETVFRMATVNGARALGLKAGIIKEGYLADIAIIDFNKPHLRPINNVISHLVYSANGNDVETTIVDGKVLMLDRELFTLDEEKILNDAERVIGELT
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: MSBA_PSEAE
Sequence: MSDSPQNPGPSSLKIYFRLLGYVKPYIGMFLLSIVGFLIFASTQPMLAGILKYFVDGLSNPDAALFPNVQWPWLRDLHLVYAVPLLIILIAAWQGLGSFLGNFFLAKVSLGLVHDLRVALFNKLLVLPNRYFDTHSSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVFLFLYLLWMNWKLTLVMLAILPVIAVMVTTASRKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEEKRFLDASQSNTDKQLRMTKTGAVYTPMLQLVIYVAMAILMFLVLWLRGDASAGDLVAYITAAGLLPKPIRQLSEVSSTVQRGVAGAESIFEQLDEAAEEDQGTVEKERVSGRLEVRNLSFRYPGTDKQVLDDISFIAEPGQMIALVGRSGSGKSTLANLVPRFYQHNDGKILLDGVEVEDYRLRNLRRHIALVTQQVTLFNDSVANNIAYGDLAGAPREEIERAAKAANAKEFIDNLPQGFDTEVGENGVLLSGGQRQRLAIARALLKDAPLLILDEATSALDTESERHIQAALDEVMKGRTTLVIAHRLSTIEKADLILVMDQGQIVERGSHAELLAQNGHYARLHAMGLDEQAPAPVG
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEP1_EHV2
Sequence: MDPLKLFTGVPKKEYPTAPKTVTPLYPNPMVCRMVLEVNRCENLCVACNSPVLVRDGALCVSQTLDYVKQKLVSDTFMGFTMACLLDCEDLVDSINLAPHVFAQRVFVFRPPNSYLLEMCVLSSMLENCETYTRRFVESLVSRARFIYSKSPCIDACFLLHSIEMMASTIIDYFKLDLEGTQPRYPGLMMYKLHGAIEGGSFESKGLLRPIYHESFKLCSDPDASFDEEEETGEAGVTFNVFYCETIFTKHLRAEAVAKVFKERCLEGFPRHQILS
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
What are the official names of this protein?
Cytoplasmic envelopment protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: YD152_YEAST
Sequence: MAKTSSSSSSSNREWSSSLLLSPKVDCPSKTFSLLEAKSSTSFKPYGLISSPTSEVLVLFEPLRTILFYTPTLICFLFLQNFLYKSISEMSYDEMSFIIEFFFIAEAQFENFSSALQSPIF
What are the official names of this protein?
Putative uncharacterized protein YDL152W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OLF3_CHICK
Sequence: MASGNCTTPTTFILSGLTDNPGLQMPLFMVFLAIYTITLLTNLGLIRLISVDLHLQTPMYIFLQNLSFTDAAYSTVITPKMLATFLEERKTISYVGCILQYFSFVLLTTSECLLLAVMAYDRYVAICKPLLYPAIMTKAVCWRLVESLYFLAFLNSLVHTCGLLKLSFCYSNVVNHFFCDISPLFQISSSSIAISELLVIISGSLFVMSSIIIILISYVFIILTVVMIRSKDGKYKAFSTCTSHLMAVSLFHGTVIFMYLRPVKLFSLDTDKIASLFYTVVIPMLNPLIYSWRNKEVKDALRRLTATTFGFIDSKAVQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor-like protein COR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VLMA_LECSP
Sequence: MPSTTQTTVQSIDSIDSIPTTIKRRQNDKTKTPKTKPVSKIPICPKNSSIPRLDQPSQHKFILLQSLLPITVHQLTTLVLSISRYDDYVHPFLLRLCVIIGYGYAFRFLLRREGLAIRTLGKKLGYLDGDHHPRDKVPRDSTRLNWSLPLTVGSRTVMCVLVAYDPSQQPINYLASLKWWAWLAVYLSLYPIILDFYYYCVHRAWHEVPCLWRFHRRHHTIKRPSILFTAYADSEQELFDIVGTPLLTFFTLKALHLPMDFYTWWICIQYIAYTEVMGHSGLRIYTTPPISCSWLLQRFGVELVIEDHDLHHRQGYRQARNYGKQTRIWDRLFGTCADRIETNPVNIQKGRRVMMHSINIPSLGN
What is the function of this protein?
Fatty acid hydroxylase; part of the gene cluster that mediates the biosynthesis of verlamelin, a lipopeptide that exhibits antifungal activity against plant pathogenic fungi (PubMed:24848421).  Verlamelin is a cyclic hexadepsipeptide and is bridged by ester bonding between a 5-hydroxytetradecanoic acid moiety and a carboxyl group on the terminal Val of amide-bonded tetradecanoyl-hexapeptide D-allo-Thr-D-Ala-L-Pro-L-Gln-D-Tyr-L-Val (PubMed:24848421).  VlmA and vlmB are altogether regarded as essential components in the biosynthesis of 5-hydroxytetradecanoic acid (PubMed:24848421).  VlmA catalyzes the hydroxylation at position C5 of tetradecanoic acid produced in primary metabolism, while the precise function of vlmB still remains to be solved (PubMed:24848421).  To be loaded onto the waiting NRPS, 5-hydroxytetradecanoic acid is activated in the form of acyladenylate by the AMP-dependent ligase vlmC (PubMed:24848421).  VlmS seems to accept the fatty-acyl intermediate onto the initial module to further elongate amino acid residues by the downstream modules (PubMed:24848421).  In addition, in the last module at its C-terminus, vlmS contains a surplus condensation (C) domain that may be involved in cyclization, the last step to form verlamelin (PubMed:24848421).
What are the official names of this protein?
Fatty acid hydroxylase vlmA, Verlamelin biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family. TMEM195 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ODB2_MOUSE
Sequence: MAAARVLRTWSQNAVRLTCVRYFQTFNSARVLKPKCVCSVGYPLFKYSQPRHSLRTAAVLQGQVVQFKLSDIGEGIREVTIKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKRLYYNLDDIAYVGKPLIDIETEALKDSEEDVVETPAVSHDEHTHQEIKGQKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILSFLEKQTGAILPPSPKSEITPPPPQPKDRTFPTPIAKPPVFTGKDRTEPVTGFQKAMVKTMSAALKIPHFGYCDEIDLTQLVKLREELKPVALARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTELGLIVPNVKNVQVRSVFEIAMELNRLQKLGSSGQLGTTDLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGAIKALPRFDQKGDVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDLK
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).  Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
What are the official names of this protein?
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial, Branched-chain alpha-keto acid dehydrogenase complex component E2, BCKAD-E2, BCKADE2, Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, Dihydrolipoamide branched chain transacylase, Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PEX7_ARATH
Sequence: MPVFKAPFNGYSVKFSPFYESRLAVATAQNFGILGNGRIHVLELAPGAPGVTESVSYDTADAVYDVCWSESHDSVLIAAIGDGSVKIYDTALPPPSNPIRSFQEHAREVQSVDYNPTRRDSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPKHGDVFASASGDCTLRIWDVREPGSTMIIPAHDFEILSCDWNKYDDCILATSSVDKTVKVWDVRSYRVPLAVLNGHGYAVRKVKFSPHRRSLIASCSYDMSVCLWDYMVEDALVGRYDHHTEFAVGIDMSVLVEGLMASTGWDELVYVWQQGMDPRAS
What is the function of this protein?
Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal (PubMed:15548601, PubMed:15637057, PubMed:17478547, PubMed:19594707, PubMed:20130089).  Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol (PubMed:15548601, PubMed:15637057, PubMed:17478547, PubMed:19594707, PubMed:20130089).  Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:15548601, PubMed:15637057, PubMed:17478547, PubMed:19594707, PubMed:20130089).
What are the official names of this protein?
Peroxisome biogenesis protein 7, Peroxin-7, AtPEX7, Peroxisomal targeting signal type 2 receptor, Pex7p.
What is the protein family that this protein belongs to?
Belongs to the WD repeat peroxin-7 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=The loss of PEX12, PEX13 or PEX14 prevents the targeting of PEX7 to peroxisomes.
Protein: GLRX2_ECOL6
Sequence: MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVGQKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI
What is the function of this protein?
Involved in reducing some disulfides in a coupled system with glutathione reductase.  Does not act as hydrogen donor for ribonucleotide reductase (By similarity).
What are the official names of this protein?
Glutaredoxin 2, Grx2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: LPTD_SACD2
Sequence: MTKRYFSLLAVCSAIATSTFADDTPTNSLSLGKTYLRCYPQADSNQWDCAEYSSETNLPIGRSQIQQAPNAYDFVSAENLTPAAQSALLPGCTGMYIDPLGDQTNAPSPENTPLIVEADDSVLTGSQKAQLDGNVQISQGARSIRADSMTYSRETEEASLAGGVTIRNPGLLIRGDKASMSTTRNQASFENAIFVLHGQHIRGQADAIRQTSDSSIVLEGGSITSCEPGSNAWSLGGAEIKIDNEKGQGTGKHITLKVGKVPIMYVPYIAFPLGDQRQSGLLFPSISSSDNGGLDAAVPFYWNMAPNYDATITPRIISGRGAMLEVEGRHLNKSFYTESNIAYLPNDDGGQDKDLDTLVSNGDITESQAHPYTGQNRWLGHLSQQGGSASNGGWYSTIDFTKVSDQDYFRDLGASSFSEQNQSYLDQRAELGYLFEHWTVSAMAQNRQVLLYDLDTPYRRAPQLNAIGHYSVNGFEFKLDNELVRFDHPSNEWRNGDTLITGSRLSTDYRAAWPIRGRWGFIKPEVGYKALGYQLESDGLASSAESSPTLGAAQASIDMSVIFEHRGGSIMQTIEPRVYYLHRAYTDHSDLYAVTADGQNVNFDTSIRTFSYSQLFRDSRFGGRDRLDDANQTTVGLTSRWYSNNSGRELFSASIGQVFHNADRRVGLNGEELNTGQTSELAADVSVMLGPLSRFYVNSIYDTEAAEITRASSGVYYHSQDLSTLANLSYSYVRDYRQSSIAAGTTEATDIDQVDLSFVTPINKQWSLMGRYNYDFTQAQELETFLGFEYNDCCYRVRLLARKWLDSNIASLTDNHDLEHDQGVFFEVHFKGLGGSGAKVNSILEDSIRGYQERERRNKQ
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GLYA_ALCBS
Sequence: MFPKSMSIAEFDPEIKAAIEAEEVRQEEHIELIASENYASPRVMEAQGSVLTNKYAEGYPGKRYYGGCENVDVVEQLAIDRACELFGADWANVQPHSGSQANGAVYMAMLKAGDTVLGMSLDAGGHLTHGAKPNFSGKTYNAVQYGLDNETGLIDYDQVASLAREHKPKMIVAGFSAYSQIVDWQRFRDIADEVGAILLVDMAHVAGLVAAGVYPSPVGIADITTTTTHKTLGGPRGGLIMGKASEEIQKKINSAVFPGGQGGPLEHVIAAKAICFKEAMQDDFKGYQQQVVKNAQAMAGVFIERGFDVVSNGTENHLFLLSLIKQDITGKDADAALGRANITVNKNAVPNDPRSPFVTSGLRIGSPSITRRGFDEADAKALAGWICDILENMGDEGVIEQVKGKVKEICARLPVYER
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH3R1_DANRE
Sequence: MDESALLDLLECPVCLERLDATAKVLPCQHTFCRRCLLGIVGSRGELRCPECRTLVESGVDELPSNILLVRLLDGIKQRPRRTGSVHGTCANGSAVAGVRAQGAGGSQRDPGPTGGQSQRVQAKSTPVRGVPQLPCAKALYNYDGKEPGDLKFSKGDIIILRRQVDENWYHGEMGGVHGFFPTNFVQVIKPLPQPPPQCKALYDFELKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDKIGIFPISYVEFNSAARQLIELDKPSEGGGDSSEGPSSSSSGPQANGSQKAPGEKKNSKKRHSFTSLTMSHKPCLAPPPQRHSMEISGPVLISSSNPTAAARIGELSGGLSSSAPSQVHICTTGLIVTPPPSSPVTTATVFTFPPETSYASIPVDALPPPPPPPPQSQSSVVGAAALNAGQRPSPAAGDQSGRQRPTVYVAMFPYSPRKEDELELRKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVSRTVSGSSQPKVPLTLCSQAGRGVTIVSPSSALGSMDLSKPLPVCPNATPSCSLPAAVVTAAHLPTGQHPKVLMHVTSQMTVNQARNAVRTAVSHSQDRPTAAVTPIQSHNPVAYLPSTAVVLQASPVLNSSSGCSSARVGVALGCAAASLTPPNVSAASLDTDAMRPVPMVALPVNAGSTKPLGAASNHGVACRLDKDCKREKKGLLKLLSNKKKLRPSPPSSPTLEAEQSVSMELPQGAVGPEMALSGSAGHNGRIGACPMDSELSMSSSSSNTDAVTHRSSPQDNTAPIAPPPRQPCSSLLSMQHDGRPIVCERYRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGRTGLFPGSFVDSI
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity.  In the absence of an external substrate, it can catalyze self-ubiquitination.  Acts as a scaffold protein that contributes to the effective activation of the JNK signaling pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF1, Plenty of SH3s, Protein POSH, RING-type E3 ubiquitin transferase SH3RF1, SH3 domain-containing RING finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell projection, lamellipodium. Golgi apparatus, trans-Golgi network.