PharMolix/UniProtQA huggingface dataset:
Protein: CL12B_HUMAN
Sequence: MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGCAYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD
What is the function of this protein?
Inhibitory receptor postulated to negatively regulate immune and non-immune functions (PubMed:17562706, PubMed:34310951).  Upon phosphorylation, recruits SH2 domain-containing PTPN6 and PTPN11 phosphatases to its ITIM motif and antagonizes activation signals (PubMed:17562706, PubMed:34310951).  Although it inhibits KLRK1/NKG2D-mediated signaling, it does not bind known ligands of KLRK1/NKG2D and therefore is not its inhibitory counterpart (PubMed:17562706).  May limit activation of myeloid cell subsets in response to infection or tissue inflammation (PubMed:17562706).  May protect target cells against natural killer cell-mediated lysis (PubMed:17562706).  May negatively regulate cell cycle and differentiation of melanocytes via inactivation of STAT3 (PubMed:34310951).
What are the official names of this protein?
C-type lectin domain family 12 member B, Macrophage antigen H.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: ENGB_LEGPA
Sequence: MPINLYSKAVFLKSAARVNQLPEDSGYEVAFAGRSNAGKSSALNCLTNNKNLARTSKTPGRTQLINLFSLDEQRRLVDLPGYGYAKVAMEVKLEWQKNLAHYLEARQCLRGLILLMDVRHPLKDLDQILVNWALHRELPVHILLTKADKLSRSEVKNAVLKVRQYYELAEHLVSVQAFSSVKKDGVEELISVLDRWYEWN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SER1_DROME
Sequence: MKLFVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGSGDIIQHHHYNSGNLHNDISLIRTPHVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSPLPDWLQSVDVQIISQSDCSRTWSLHDNMICINTDGGKSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSGAPAVFSRVTGYLDWIRDNTGISY
What is the function of this protein?
Major function may be to aid in digestion.
What are the official names of this protein?
Serine protease 1, Protein Jonah 99Cii.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: BAME_SHIDS
Sequence: MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLTNIDNKPALSGN
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PSD_MYCGI
Sequence: MARRPDLKTGPERLAALVRTTVPPMHPAGLPFVGASLAVALAGRKSRWLRNAGVASAAANAAFFRHPPRTPPTRPGVVVAPADGLICLIEDELPPAELELPAVPLPRISIFLSLFDAHVQRAPLAGEVVAVEHRPGLFGSAELAAASADNERNSVVIRSPEGAEVIAVQIAGLLARRIVCNVKSGDKVGLGDTYGLIRYGSRLDTYLPAGSDVLVEVGQRAVAGETVLAELP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HXB5_SHEEP
Sequence: SAPDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHA
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B5, Homeobox protein Hox-2.1, OHox-2.1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECA_CHLT2
Sequence: MSVPDRKRALEAAIAYIEKQFGAGSIMSLGKHSSAHEISTIKTGALSLDLALGIGGVPKGRIVEIFGPESSGKTTLATHIVANAQKMGGVAAYIDAEHALDPNYAALIGANINDLMISQPDCGEDALSIAELLARSGAVDVIVIDSVAALVPKSELEGEIGDVHVGLQARMMSQALRKLTATLARTNTCAIFINQIREKIGVSFGNPETTTGGRALKFYSSIRIDIRRIGSIKGGENFDIGNRIKVKVAKNKLAPPFRTAEFDILFNEGISSAGCIIDLAVEKNIIDKKGSWFNYQDRKLGQGREAVREELKRNKELFHELERRIYESVQASQAPAAACVDSESREVAEAAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSG1_MAIZE
Sequence: MAALATSQLVATRAGLGVPDASTFRRGAAQGLRGARASAAADTLSMRTSARAAPRHQQQARRGGRFPSLVVCASAGMNVVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVVSPRYDQYKDAWDTSVVSEIKMGDGYETVRFFHCYKRGVDRVFVDHPLFLERVWGKTEEKIYGPVAGTDYRDNQLRFSLLCQAALEAPRILSLNNNPYFSGPYGEDVVFVCNDWHTGPLSCYLKSNYQSHGIYRDAKTAFCIHNISYQGRFAFSDYPELNLPERFKSSFDFIDGYEKPVEGRKINWMKAGILEADRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSRDKYIAVKYDVSTAVEAKALNKEALQAEVGLPVDRNIPLVAFIGRLEEQKGPDVMAAAIPQLMEMVEDVQIVLLGTGKKKFERMLMSAEEKFPGKVRAVVKFNAALAHHIMAGADVLAVTSRFEPCGLIQLQGMRYGTPCACASTGGLVDTIIEGKTGFHMGRLSVDCNVVEPADVKKVATTLQRAIKVVGTPAYEEMVRNCMIQDLSWKGPAKNWENVLLSLGVAGGEPGVEGEEIAPLAKENVAAP
What is the function of this protein?
Required for the synthesis of amylose in endosperm.
What are the official names of this protein?
Granule-bound starch synthase 1, chloroplastic/amyloplastic, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule-bound.
Protein: FENR_ACIC1
Sequence: MLIVGAGPAGLYAAYYAGFRAMSVVVLDSLTEPGGQLAALYPEKVIYDVGGIPAILGRELAADLYKQAMTYNPVMLLGHGADQLFRLDDGSFLVTTTTGLLIHAKAIIVTAGIGVFTPRRLPVGQEYEGRGLRYFVPNPQELAGKRILVVGGGDSAVDYALMLEKVAASVTLIHRRHEFRAHEASVEQLRASSVRILTPYQVSAVYGDDRVTAVDVTDHDTKHVERLDVDEIVAALGFVAELGPLAEWGMELRQRHIVVDTTMATSVPRIYAAGDIADYPGKVKLISVGFGEAAIAVNNAAVAIDPSKKLFPGHSSDPDRHPTER
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: YL218_MIMIV
Sequence: MTINGLLIKISPKKFFNTKAESEKYAAREMIQHIKTFSSQSHYSPNSETKQSHIIPSQCTTKKYTISDNTNNTIDTNKQQDTLKQLDFSKKCVIENIHDHYFTKIYIIDLENKPQLNLVPRQDSIYLGFINSLHHSVGKYSDWYNCTNDNIAEQISTSGNNKLLYCIDGGISDLSDHFMTAFIYPIINYISSRITNKFENTRTSICIISGDHAGYCTRYCLEKMIRWNKLSNIDVSNSIIVD
What are the official names of this protein?
Uncharacterized protein L218.
Protein: ARGA_ALIF1
Sequence: MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVIVYGTRPQMRSLLKQTEHHAPFHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGINRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKELTPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQVRDAEIDDIGGILDLIRPLEEEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPEEGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQLFVLTTRSLHWFREQGFIEVDVSHLPIKKQKLYNFQRKSKILVLKGL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA_ECO55
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMCQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: GPMA_PARUW
Sequence: MVKLILMRHGQSQWNLANLFTGWVDIPLSFKGIEEAIEAGKQIKNYPIDLIFTSSLIRAQMTAMLAMSVHTSGKVPVILHTGEGRLEEWASIYSSESQSQTIPVIRAWELNERMYGELQGINKEEMAKKYGAEQVHIWRRSFDVPPPNGESLQMTAARTIPYFENTIVPHLKEKKNIFIAAHGNSLRSIIMKLDGLTTDQVVKLELATGVPVIYDFNHDEYIKQQK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: DAPAT_DEHMB
Sequence: MKLSKRIENLPPYLFVQISKKIAEKRAKGEDVISFAIGDPDLPTPKHILAELCKAAEDPSNHRYPETEGLPVLRKAMAEWYQKRFGVKLNPDTEVLPLIGSKEGIGHAAWCFLDPGDIALVPNPAYPVYAISSQLAGAEVFNLPLNKGNNFLPNLEAIPQNILSKAKVLWINYPNNPTGAVAGLSFFQEVANFAAKHNLAVCHDGPYSEIAFDGYKPVSFLEADGAKDVGIEFHSLSKSYNMTGWRIGMAVGNAKMIDALRRFKSNLDSGIPQAIQLMAIAALNGSQEIINQNCAIYQRRRDRLVEALRNIGMEVTAPKASLYIWAPVPESYTSASFATELLDKTGVVVTPGTGYGTAGEGYIRLSLTVPDEQIEKGIAKLAGYKKSS
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: YHHN_ECOLI
Sequence: MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQAPMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSFFWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALSAFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL
What are the official names of this protein?
Uncharacterized membrane protein YhhN.
What is the protein family that this protein belongs to?
Belongs to the TMEM86 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLP7_YEAST
Sequence: MSSTQDSKAQTLNSNPEILLRKRRNADRTRIERQELAKKKREEQIKKKRSNKNKFVRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEKANGAEENSVDLEETEEEEDDGLIREKTTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKNVYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKGENEAEPHEIVLNDNNIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGSLNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs.
What are the official names of this protein?
Ribosome biogenesis protein RLP7, Ribosomal protein L7-like.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y081_PHOLL
Sequence: MTVSLPSHSVSRDAPDRLMLNRLPARAGIGLKPEHFRAILHNKPDIGFFEIHAENYLVAGGPFHQALTTIRQDYPLSIHGVGLSIGGENPLNQTHLQRVAALVERYQPAVFSEHLAWSTHNDLFLNDLLPLPYTDVTLTRVCEHIDQVQNALRRPILLENPSTYIEFSASTMSETDFISEVVRRTGCGLLLDVNNLYISGVNHNRCPRQMLLELPLHRVGEIHLAGYTESRDGANDLLLIDSHDSHVTGPVWDLYNKTLRKTGPIATLIEWDSNIPPLDVLLNEASHAQHYITESKKHATTTVSSTS
What are the official names of this protein?
UPF0276 protein plu0081.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: RL14_ACTPJ
Sequence: MIQEQTMLDVADNSGARSVMCIKVLGGSHRRYAAIGDIIKVTVKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNTEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PYC1_MASLA
Sequence: GRLFKITACVPSQTRIRTQRELQNTYFTKLVPYENWFREQQRIQKMGGKIVKVELATGKQGINTGLA
What is the function of this protein?
Rod linker protein, associated with allophycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 7.8 kDa linker polypeptide, allophycocyanin-associated, core, LC 7.8.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with allophycocyanin.
Protein: EFTU_STIHE
Sequence: MARAKFERKKPHVNIGTIGHVDHGKTTLTAAITMALAARGGATGRKYDEIDSAPEEKARGITINAAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTTEHVLLAKQVGVPAIVVFLNKADQVDDPELLELVELEVRDILDKYGFASDEVQILSGSALLALEALVENPNIKPGDSEWVDKIYNLMATVDEHIPTPKREMDKPFLLAVEDVFSITGRGTVATGRVERGTLKVNETVEIIGLRDTKTTTVTAIEMFQKTLDETIAGDNVGILLRGVQKKDIERGMVIAKPGTILPHTLFEGQVYVLTAEEGGRKSGFFKGYQPQFYVRTTDVTGKILDFSYIKQRNPSELSTMHSNPMVCPGDYVNMKIQLITPIAIEKGMRFAIREGGRTVGAGMVLEILES
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADEC_ECOL5
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIDRQPVSASDFALQFTPGKRYRVIEVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CAPP_STRAW
Sequence: MSSADDQTTTTSSELRADIRRLGDLLGETLVRQEGPELLDLVEKVRRLTREDGEAAAELLRGTELETAAKLVRAFSTYFHLANVTEQVHRGRELRTKRAAEGGLLARTADRLKDADPEHLRATVKNLNVRPVFTAHPTEAARRSVLNKLRRIAALLETPVIEADRRRYDTRLAENIDLVWQTDELRVVRPEPADEARNAIYYLDELHAGAVGDVLEDLTAELERVGVQLPDDTRPLTFGTWIGGDRDGNPNVTPEVTWDVLILQHEHGINDALELIDELRGFLSNSIRYTGATEELLTSLGTDLERLPEISPRYKRLNAEEPYRLKATCIRQKLENTKQRLAKGTAHQPGRDYLGTGELLHDLKLIQTSLREHRGGLFADGRMDRTIRTLAAFGLQLATMDVREHADAHHYALGQLFDRLGEESWRYADMPRDYRGKLLAKELRSRRPLAPSPAPLDAAGAKTLGVFHTVKRALAVFGPEVIESYIISMCQGADDVFAAAVLAREAGLLDLHAGWAKIGIVPLLETTDELKAADTILEDMLSDPSYRRLVALRGDVQEVMLGYSDSSKFGGITTSQWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPSHDAILAQPWGTLEGEIKVTEQGEVISDKYLVPSLARENLELTVAATLQASALHTAPRQSDEALARWDAAMDVVSDAAHSAYRRLVEDPDLPTYFLASTPVDQLADLHLGSRPSRRPGSGVSLDGLRAIPWVFGWTQSRQIVPGWFGVGSGLKALREAGLDTVLDEMHEQWHFFRNFLSNVEMTLAKTDLRIARHYVDTLVPDHLKHVFATIEAEHELTVREVLRITGGEKLLDTHPVLQQTFAIRDAYLDPISYLQVALLKRQRDAAAADTPPDPLLARALLLTVNGVAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: SYV_THEMA
Sequence: MAELSTRYNPAEIETKWYRYWEEKGYFTPKGVGEKFSIVIPPPNITGRIHMGHALNITLQDIVVRYKRMKGYDVLWVPGEDHAGIATQNAVEKFLLQTQGKTREEIGREKFLEITWEWANKYRREIREQIKALGASVDWTRERFTLDEGLSRAVRKVFVELYRKGLIYRGKYIVNWCPRCKTVLSDEEVEHKEHKSKLYYVKYPVKDSDEYIVVATTRPETMLGDTAVAVHPEDERYKNFVGKTLILPLVGREIPVVADKYVDPKFGTGAVKVTPAHDPNDYLIAQRHNLPMIEIFDDNARINENGGKYKGLDRYEAREKIVKDLEEQGFLVKIEDYTHSVGHCYRCDTVIEPKLSDQWFVSTKPLAKRAIEAVENGEIRFFPERWTKVYLNWMYEIRDWCISRQLWWGHRIPVWYCQDCGHLNVSEEDVEKCEKCGSTNLKQDEDVLDTWFSSALWPFSTLGWPEETEDLKRYYPTDLLVTGFDIIFFWVARMIMMGYEFMNDKPFSHVYIHQLVRDKYGRKMSKSLGNGIDPLEVIDEYGADPMRFTLAILAAQGRDIKLDPRYFDAYKKFANKIWNATRFVLMNLEDYKEVPLENLKTVDKWILTRLNKTVEEVTNALENYDFNIAARTIYNFFWDDFCDWYIEASKPRLKTEERNLVQTVLVKVLDASLRLLHPFMPFLTEELWQKLPVAGESITIAKWPEIERELIDETAEKEFTRLMNMVRGVRNVRAEMNLPQSQRVKVYIKGYEVTEEEELLLKTLGNIEEVSFVNEKPPKTATAYVEEEIEAYVDLGGLIDFEKEKERLKQIMEKIQKEIDRLEKKLANKDFVEKAPEEVVEETKEKLNTNRERLARLESILRDLE
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_STRMK
Sequence: MRVLVLGSGVIGTTSAWYLRQAGFEVTVIDRQPGPALETSFANAGQLSFGYTSPWAAPGVPKKAIGWLFEKHAPLAIKPGMDLAQYRWLWQMLRNCTHERYAINKARMVRMSEYSRDCLNELRAQIGIEFEGRDLGTTQLFRTQQQLDASAQDIEILAQYGVPYEVLDRAGIIQAEPALAHVDGLVGALRLPRDQTGDCQLFTRRLAQMCVDAGVEFRFDQDITGLEFDGDRITGVRIDGKLETADRFVVALGSYSPALVAPLGMRLPVYPLKGYSLTLPITDPAMAPTSTILDESYKVAVTRFDDRIRVGGMAEVAGFDLSLSQRRRETLELVVSDLYPKGGDLSRAQFWTGLRPATPDGTPVIGATPFRNLYLNTGHGTLGWTMACGSGRYLADLMSARQPQISTEGLDIFRYGQYGHAPQQENRTCVLPAR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: LEU1_PARP8
Sequence: MADKLIIFDTTLRDGEQSPGASMTKEEKIRIAKQLERMKVDVIEAGFAASSNGDFDAIHTIAGMIKDSTICSLARANDKDIQRAADALKPADHFRIHTFIATSPLHMEKKLRMSPEQVLEQAKLAVRFARKFTNDVEFSPEDGSRSDMDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAVFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNTSLEEIVMAVRTRKDYFGLDLGIDTTQIVPASKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGISLDSESELNLAFQRFKELADRKAEIFDEDIIAIVTEESAEAQEKEHYKFVSLSQHSETGERPHARIVFSVEGKEVVGEANGNGPVDATLNAIETEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKAGRIVNGVGTDPDIVAASAKAYISALNRLYAGADKLNPQRADI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SSRP_SALG2
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: S66AL_HUMAN
Sequence: MKVVGNYRVNTANSSTDTSGEHLTCLRSQLFVAYRNGRVDEAVSLGFLDCWIGGDLTNFKGCYLTNQLPIQIFTAIFDMNTDVIILSQFMYYRLKNQKKKMIFQPQLFKDSITREKVRLSLWGVLCPVYIPYSFR
What are the official names of this protein?
Putative uncharacterized protein SLC66A1L, PQ-loop repeat-containing protein 2-like, Solute carrier family 66 member 1-like.
Protein: GCSP_XANC5
Sequence: MSQTPSSLRDLEHHSAFVERHIGPNDAEIAQMLDVVGHACLDALTDAIVPGNIKSPAPLALPEAITEEEALAKIRAIADKNTVFRNFIGQGYYGTHTPKVILRNILENPAWYTAYTPYQAEISQGRMEALINFQTLCADLTGMQIANASLLDEATAAAEAMTLAKRSAKSRSNTFFVHDAVHPQTLELLRTRAEPLDIVLRVGTPEEALQAECFGVLLQYPDSFGHIGDHAALADAVHAQGGLVAVATDLLALTLIAAPGEWGADIVVGNSQRFGVPFGFGGPHAAFMACRDAYKRSMPGRLIGVSIDAAGNPAYRLTLQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPDGLTRIARRTHRLAAILAAALRSAGVTVGERFFDTLHVKAIDANAIHARARAAGINLRAIDSEAVGISLDETSTRADVVALAALFGAQADVDALDAATADALPQGLLRTTPFLTHPVFNTHHSEHELLRYMRSLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWPEFGAIHPLAPAEQSAGYAQLIDELEAMLVECTGYDAVSLQPNSGAQGEYAGLLAIRAYHRSRGEAHRDICLIPESAHGTNPASAQMCGMTVVVTKCDANGNVDVDDIRAKAEKYSDRLAALMITYPSTHGVFEEDVVAICEAVHAHGGQVYTDGANMNALVGVAKPGKWGSDVSHLNLHKTFCIPHGGGGPGVGPCAVKSHLAPYLPKTLGGEGDVGMVSAASYGSASILPISWMYVTMMGSAGLRKATQVALLNANYIAKRLAPHYKTLYTGRNGLVAHECILDVRPLEKTSGIGAEDIAKRLIDFGFHAPTLSFPVAGTLMVEPTESESQHELDRFIDAMIQIREEIRAIEDGRLDREDNPLKHAPHTATQVSASEWTHAYPRELAAFPLPSLKQQKYWPPVARVDNVYGDKNVMCACIPVDAYKEDVEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: FGF10_MOUSE
Sequence: MWKWILTHCASAFPHLPGCCCCFLLLFLVSSFPVTCQALGQDMVSQEATNCSSSSSSFSSPSSAGRHVRSYNHLQGDVRWRRLFSFTKYFLTIEKNGKVSGTKNEDCPYSVLEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMTIQT
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation.  Required for normal branching morphogenesis.  May play a role in wound healing.
What are the official names of this protein?
Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.