PharMolix/UniProtQA huggingface dataset:
Protein: PEPT_STAHJ
Sequence: MKAQLIDRLSRYVKIDTQSNPESSTTPSTEKQWDLLRLLQQELEGFGLETNLDDNGYLFATLESNVSFDVPTVGFLAHVDTSPDFNASNVNPQIVEQYDGKTIKLGDTGRVLSQETFPELKKLIGHTLMITDGTSLLGADDKAGVVEIMEAVKYLIEHPEIKHGRIRIAFTPDEEIGRGPHKFDVERFNADFAYTMDGSEFGELQFESFNAAEANITTHGVNVHPGSAKNIMVNAISLGHQFHSLLPAGEVPERTEDYEGFYHLMKFEGNVEKATLQYIIRDHDRESFELRKKKLLEIRDDINVHYEDFPVKVDIEDQYYNMAEKIEPHPYIIDIPKKVFNDLNIEPNTAPIRGGTDGSQLSFKGLPTPNIFTGCGNFHGPFEYASIDVMEKAVQVIIGIAQEVTHHHK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN19_ORYSJ
Sequence: MCSWSLSSHTLTSPVRQAAMEPKSSSCGGAGIRLRLLVVLHLLLLVPSSAMAFNYADALAKSIIFFEGQRSGKLPPGNRMPWRADSGLTDGAQYNVDLVGGYYDAGDNVKFGLPMAFSTTMLAWSVLDFGKFMGAELPNARAAVRWGADYLLKAATATPGALYVQVADPNQDHRCWERPEDMDTPRSVYRVTADKPGSDVAGETAAALAASSMVFRRADPAYSARLLHAATQVFDFADRHRGSYSDSLASSVCPFYCSYSGYHDELLWGASWLHRASRNASFMSYVEANGMQLGAGDDDYSFSWDDKRVGTKVLLAKGFLRNRLHGLELYKAHSDSYICSLVPGTASFQSRYTPGGLLYREGSSNMQYVTTATFLMLAYAKYLRSSGATASCGDGGGGARGEVSAAELVAVAKRQVDYILGKNPAGMSYMVGFGCRYPRRAHHRGASMPSVRAHPGRISCDAGFGYLHSGEPNPNVLVGAVVGGPDSRDAFADDRGNFAQSEPATYINAPLVGALAYFAGTTK
What are the official names of this protein?
Endoglucanase 19, Endo-1,4-beta glucanase 19.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_SALRD
Sequence: MARIGDNPIPFGDEVTVSVDDHNVVTIEGPKGTLTEQIDPEMTLDIADDHVVVRRPTNQKRHRSLHGLSRSLIVNMVEGVTEGYKKELKIIGVGYRAQMSDETLEIALGYSHPIYFLPPSDVAVSVDSDRGQDDIIIVEGIDKELVGQVAAKIRSLRPPEPYKGKGVRYVDEHVPLKAGKTAAR
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DCTA_SALA4
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDVIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQLGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDHQKLDDVLNNRAPDGKTHEISS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACPS_SHESR
Sequence: MAIVGLGTDIVEIERITAHVARSGDKLAKRVLTEAEFEIYQQHSQPSRYLAKRFAAKEAAAKALGTGIGRGVSFQHIHIGNTPDGAPTIDFTQGAQQRLALLNGVVGHISIADEKSYAIATVILESR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASM_HUMAN
Sequence: MPRYGASLRQSCPRSGREQGQDGTAGAPGLLWMGLVLALALALALALALSDSRVLWAPAEAHPLSPQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYEAMAKAWEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPGHCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGLNPGYRVYQIDGNYSGSSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPDGSLPEAQSLWPRPLFC
What is the function of this protein?
Lacks residues that bind the cofactor Zn(2+) and has no enzyme activity.
What are the official names of this protein?
Sphingomyelin phosphodiesterase, Acid sphingomyelinase, aSMase.
What is the protein family that this protein belongs to?
Belongs to the acid sphingomyelinase family.
What are the subcellular locations of this protein?
Lysosome. Lipid droplet. Secreted. Note=The secreted form is induced in a time- and dose-dependent by IL1B and TNF as well as stress and viral infection. This increase of the secreted form seems to be due to exocytosis of the lysosomal form and is Ca(2+)-dependent (PubMed:20807762, PubMed:22573858, PubMed:20530211). Secretion is dependent of phosphorylation at Ser-510 (PubMed:17303575). Secretion is induced by inflammatory mediators such as IL1B, IFNG or TNF as well as infection with bacteria and viruses (PubMed:12563314, PubMed:20807762).
Protein: FHN1_YEAST
Sequence: MLSAADNLVRIINAVFLIISIGLISGLIGTQTKHSSRVNFCMFAAVYGLVTDSLYGFLANFWTSLTYPAILLVLDFLNFIFTFVAATALAVGIRCHSCKNKTYLEQNKIIQGSSSRCHQSQAAVAFFYFSCFLFLIKVTVATMGMMQNGGFGSNTGFSRRRARRQMGIPTISQV
What is the function of this protein?
Involved in membrane organization.  Required for the formation of membrane compartments of CAN1 (MCCs), localization of CAN1 at the MCCs and subsequent invagination of the plasma membrane at the MCCs sites.  Involved in eisosome organization and might act as a sensor of sphingolipids that regulates plasma membrane function.  Involved in a novel pathway of export of proteins that lack a cleavable signal sequence.  Non-classical export pathway functions also as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient.
What are the official names of this protein?
Non-classical export protein 2 homolog 1, Functional homolog of NCE102.
What is the protein family that this protein belongs to?
Belongs to the NCE102 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Associates with the ergosterol-rich membrane compartment of CAN1 (MCC). Accumulates in membrane domains at eisosomes.
Protein: RR20_CYAPA
Sequence: MANTKSAIKRIKTIERNRIRNCAYKSVVKTFIKKYLKVLSDYTNAPNSNGVENIQTTLGIVYTKIDKAVKRGVYHSNKAARMKSKLALKYNVIKK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
Cyanelle 30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: CYB_MICCF
Sequence: MTIIRKKHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFMHVGRGIYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDTDKIPFHPYYTIKDFLGVLLLLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPLLHTSKQKTLTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQAASIAYFTIIVILMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TXVE2_MACLB
Sequence: QVRPFPDVYQRSACQARETLVSILQEYPDEISDIFRPSCVAVLRCSGCCTDESLKCTPVGKHTVDMQIMRVNPRTQSSKMEVMKFTEHTACECRPRRKQGEPDGPKEKPR
What is the function of this protein?
Snake venom VEGFs may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein increases vascular permeability and angiogenesis probably through VEGF receptor (KDR/VEGFR-2) signaling (PubMed:12021274).  Induces DNA synthesis in human umbilical vein endothelial cells, and promotes mouse embryonic stem cell proliferation and differentiation (PubMed:12021274).  It may also induce a drastic hypotensive effect after intravenous injection (By similarity).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase (By similarity).
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin ICPP, svVEGF, Increasing capillary permeability protein, Increasing capillary-2, IC2, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPZ_SYNP1
Sequence: MAEFYQLCRELFTTSLVLMAIAFGTVWVIYDLNTALNYLLGASASLIYLRLLARNVERLGHDQKKLGKTQLLVVVAVIILAARWHELHIIPVFLGFLTYKAAILVYMLRTVLPSP
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HBAD_STRCA
Sequence: MLTADDKKLIQQIWEKVGSHLEDFGAEALERMFITYPQTKTYFPHFDLHPGSEQIRGHGKKVANALGNAVKSLDNLSQALSELSNLHAYNLRVDPVNFKLLSQCFQVVLAVHMGKDYTPEVHAAYDKFLTAVAAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: S26A2_BOVIN
Sequence: MSLKNEDQNDLSPKDSVKGNDQYRAPSGIHLEPEEESRNDFWQFEPSNLFRHPRIHLEPQEKSDNNFKKFVIKKLEKSCQCSSTKAKNTIFGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASLIYFILGTSRHISVGIFGILCLMIGEVVDRELYIAGYDTVHAASNESSLVNQISDKTCDRSCYAIIVGSTVTFVAGVYQVAMGFFQVGFVSVYLSDALLGGFVTGASFTILTSQVKYLLGLSLPRSAGVGSLITTWLHVFRNIRKTNICDLITSLLCLLVLLPTKELNERFKSKLKAPIPVELFVIVAATLASHFGKLNEKYGTSIAGHIPTGFMPPKAPDWNLIPRVAVDAIAIAIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCQTQVSGVMTALVLLLVLLVIAPLFFSLQKSVLGVITIVNLRGALCKFKDLPQMWRISRMDTVIWFVTMLSSALISTEIGLLTGVCFSMFCVILRTQKPKASLLGLVEDSEVFESMSAYKNLQAKSGIKIFRFVAPLYYVNKEYFKSVLYKKTLNPVLVKAAQRKAAKRKIKRETVTPSGIQDEVSVQLSHDPLEFHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAVGIQVLLAQCNPSVRDSLARGEYCKKDEENLLFYSIYEAMTFAEDSQNQKERHIPNGPNFSSD
What is the function of this protein?
Sulfate transporter.  May play a role in endochondral bone formation.
What are the official names of this protein?
Sulfate transporter, Solute carrier family 26 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS16_FRATO
Sequence: MVVIRMARGGAKKRSFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: H2AZ_ASPOR
Sequence: MPGGKGKSIGGKAGSKDSAGKAQKSHSAKAGLQFPCGRVKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPRINRALLLKVEQKKKNKTEA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and spt15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NAGK_HAEIN
Sequence: MYYGLDIGGTKIELAVFNEKLEKLYSERVPTPKTDYEEWLNTIVDLVNRADEKFGEVGTVGLGVPGFVNQQTGLAEIANIRVADNKPILCDLSTRLGREVRAENDANCFALSEAWDTENQQYSTVLGLILGTGFGGGFVLNGKVHSGQVGMAGELGHLQLNYHALKLLGWDNAPIYQCGCGNKACLDNYLSGRGFEMLYQDLKGETLSARKIINLFYQSNESAVDFVNLFVELAAISIGNIITAFDPHMIVLGGGLSNFDYLYEALPKALPPHLMRKAKVPPIKKAKHGDSGGVRGAAALFLTK
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: QUEC_BURA4
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVRDALKHRFPAWAGRLGDDHMIDLSVLGAISDTAMTRTIEIETTANGLPNTFVPGRNLLFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRIVLETPLMWLDKAQTWQLAEQLGGDALVELIRVETHTCYVGERAELHDWGFGCGECPACKLRKRGYEAYLKGERVTEAPL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: VIP_MELGA
Sequence: MEHRGTSPLLLALALLSALCWRARALPPRGAAFPAVPRLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDRNDRHADGIFTTVYSHLLAKLAVKRYLHSLIRKRVSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLADEAEILEPSFSENYDDVSVDELLSHLPLDL
What is the function of this protein?
PHI also causes vasodilation.
What are the official names of this protein?
VIP peptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDE6D_HUMAN
Sequence: MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
What is the function of this protein?
Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853).  Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361).  Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846).  Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity).  Increases the affinity of ARL3 for GTP by several orders of magnitude.  Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).
What are the official names of this protein?
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta, Protein p17.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
Protein: BCHL_CHLL3
Sequence: MSLVLAVYGKGGIGKSTTSANISAALALKGAKVLQIGCDPKHDSTFPITGKLQKTVIEALEEVDFHHEELTAEDVIETGFAGIDGLEAGGPPAGSGCGGYVVGESVTLLQELGLYDKYDVILFDVLGDVVCGGFSAPLNYADYAIIIATNDFDSIFAANRLCMAIQQKSVRYKVKLAGIVANRVDYAKGGGTNMLDQFAEKVGTRLLAKVPYHELIRRSRFAGKTLFAMDDSEEGKEECLQPYLQIAEDLLSEAPMSSVPVPIGDREIFEIVGGWQ
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PXPA_PARP8
Sequence: MEIDLNADLGEGCGSDEALLDLVSSANIACGWHAGGPNAMRECVRWAVEKGVSIGAHPSFNDPENFGRKEMDLPAGEIYAGVLYQLGALSAIAQAEGGRIAHVKPHGALYNQAARDPKIADAIVSAVHDFDPSVAVFALANSGLVTAARNAGLVAIEEVFADRGYRADGSLVPRKEPGAMLDDEDEVLARTLTMVREQRVQALSGEWVPLNAQTICLHGDGPHALAFARRIRNALEAAGIGVHAANAVRV
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y1870_VIBPA
Sequence: MSELKQKQIFSEKALEKEQQSDSPELTAQKTFSEKETFVPVKIEEDRIETEQELQLEHVIRPRPGRKWLATSVFATFAGLVGWQAVDSVVTAVQTADWLALGWVGFITAVASLGLGAIGKELWKLRKLRNHFSIQEEAELLVHSDSVGKGKVFCEKVAEESGVLAENPGFDRWQNSINPAHSDAEILDMYDSMVVSQQDKLATKVVSQHATESAALVAVSPLAAADMLLVAWRNFKMIDNLSKVYGVELGYASRIKLLRAVFVNMAAAGASELAIDAGMDLMSMDLAGKVSARAGQGLGVGILTARLGLKAMALLRPLPWYPDRQVKLGTIRKAVVAKVASITMKP
What are the official names of this protein?
UPF0283 membrane protein VP1870.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCEH_SHIDS
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSANGVVTACNQKMNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRGTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTSGELRSRAARMYEFRDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDPPAVTDMLNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: HMDH_PIG
Sequence: MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLATYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEGEENKPNPVTQRVKIIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLTLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVTDDCCRREPTLVRNDQKFHTVEEEARINRERKVEVIKPLVAETDTSSRPTFVVGNSTLDSSLELEMQEPEIQIPSEPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMTPVVRFPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLQMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTSLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDLQGTCTKKAA
What is the function of this protein?
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.
Protein: PROB_LACPL
Sequence: MKVIRKLKAKRVVIKVGTSTLVYPDGSINLRAIDQLAFVISAMRHRGREVVLVSSGAIGVGLNYMGLKQRPKAIPEQQAIAAIGQTELISIYKERFAIYEQKIGQLLLTRDIFVYPKSHHNVLNTFEALLKQNVVPIVNENDTVAVDELDHETKFGDNDQLSAIVATNIGADLLIMLSDIDGFYDGNPNADARAQLLGHIEKVDQHTYKLAGGSGSRFGTGGMVTKLKAAERMIDANGQMILANGADPTIIFQILAGEPVGTLFG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP01_CAPAA
Sequence: LVVELAPMEIR
What are the official names of this protein?
Unknown protein 1.
Protein: RPOC_UREPA
Sequence: MSQKGIKSLTISIASPEQILNWSKGEITKPETINYKSLKPEPNGLFDESIFGPSKDYECYCGKYRKVKHKGKICERCHVEITESIVRRERMGHIELAAPVAHIWFTKELPSPSKISLLLDITYKEVDQVVYFVNYIVLDEGNNVYDGKSIFNKKEVLDLTSPKNSIRSRNKLRRTLRNIQERIEDELNHEREALIQDFDYRLAVTYDQMLKDSNIPFSVKDVMAFIEKHTGVRFGIGAEAIRELLEKLNLEEEHEKIKQAIQNSPNAYDQKTKRLLRRLECVRWIKDSGSKPEWMVMTRIPVTPSETRPIISLDGGRFTTSDTNNFYRKIIIRNERLKQMQATDAPEILLDNEKRLLQEAVDSLFDNNSRKKPVVGKDKRPLKSLSNHLKGKQGLFRQNLLGKRVDYSGRSVIVVGPELKMYEVGIPALMILKLFRPYIISELIRKRDELGNEIQPICANIKLAEQKILAQDNEIWPVVEKVIKQRPVILNRAPTLHRLGIQAFEPKMVDGKAIRLHPLVTTAFNADFDGDQMAVHIPLSKEAVAEARSILLASWHILGPKDGKPIITPTQDMILGIYYLTKEKFPQVIEEMMAKDPTQARVEFINNFHIFSTQDEAIRAYKLKTIRINDVIGITTKAFNNKTFSKEGILVTTVGKIIFNQAFPVNFPYINDVKNLYGENQFEIIGMHESILDYLKAYNLKEPLTKKTLSTVIDYLYKVSEIEVVPQTMDKIKALGFKYSMISATSISAFDIPSYDQKYEYFKETDELVSKLREFYLDGKLTDDERYTKVVQAWSQTKDKVTHDIEKLINSNEYKDNPIVIMAKSGARGNTSNFTQLAGMRGLMSKSYNYDQKNNNGVIKDTIEIPIKHSFIEGLSVSEYFNSSFGARKGMTDTAMKTAKSGYMTRKLVDSTQAVVIKDHDCGTKEGIIVREIRNTKDNTSIESLKDRIVGRYSINTIYDTKNKLIIESDKLITSEIANIIQNSGIREVEVRSPLHCASLYGVCQKCFGLDLSTNKLIETGTAIGVIAAQSIGEPGTQLTMRTFHTGGVAGDTNITQGFERIKQLFDCIQPQENEKAVISQVKGTVERIEKDSNTNGYNVVIKYNKDNYVNYPTRSNAVLRVKTGDEIIAGQKITEGSIDVNDLLKYAGIENVRHYIIKEVQKVYRMQGIEISDKYIEVIISQLTNKITITNPGDSGLFVGETISINEFTEVAQNMLVNKKKPPSAINQVFGLDHAPSKSGSFLSAASFQDTKKILTDAAARSQKDMLIGLKENVILGNLIPAGTGLKDVEEVIAYGEEMYKKQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RECO_DELAS
Sequence: MASAKRVSDEPAYVLHSYDWSESSLILEVFTRHRGRVALAAKGVKRPTSNFRPVLLPLQPLSLSYSLGGEGNAEIHTLKGAEWVGGHVMPQGDALMSGLYLNELLMRLLARDDPYAALFDIYAGVVRVLAGQHGDAIEPVLRTFELLLLRELGHLPALNEESATLAPLAEGRRYALVAEGGLRPALQGERAVLGAAQWQAIESALQARQAFNATLHVVAQPEQALALKPQLRALLQYHCGSPMLRTRQLMMDLQSL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ENGB_CITBB
Sequence: MIVKQTEFIKSATKPAHYPEGNLPEIAFAGRSNVGKSSLVNVLVNRKNLVRTSSTPGRTQLINFFQVNDDFMLVDLPGYGYAKVPLAVKKEWRPMMETYLSKRRNLRGVVLILDIRRTPTEEDLQMLAWLRAFSVPPIVVITKCDKVSKNERARQSAVIMEKMQLKKEELNYFSALSKEGKDAVWARIDALLSPAAAETTEISGDPAPSAPVND
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.