PharMolix/UniProtQA huggingface dataset:
Protein: PDC3_ORYSJ
Sequence: MESNGGGGGSPKEAAVVVPSSGDATLGGHLARRLVQVGVSDVFAVPGDFNLTLLDHLIAEPGLRVVGCCNELNAGYAADGYARARGVGACAVTFTVGGLSVLNAIGGAYSENLPLICIVGGPNSNDYGTNRILHHTIGLPDFSQELRCFQPLTCYQAVVNNLDDAHDQIDRAISTAIRESKPVYISVSCNLPAVPHPTFSRDPVPYFLSPRLSNQASLHAALDATLAFLDKAVKPVLVAGPKLRVAKAGGAFVDLADASGHAVAAMPSAKGLVPETLPRFIGTYWGAVSTAFCAEIVESADAYLFAGPIFNDYSSVGYSCLLKKEKAVVVQPDRVTVGNGPAFGCVMMRDFLSELAKRVRKNTTAFDNYKRIFVPEGQLPECEAGEALRVNVLFKHIQRMIGGTEIGAVMAETGDSWFNCQKLRLPEGCGYEFQMQYGSIGWSVGALLGYAQAVQKRVVACIGDGSFQVTAQDVSTMLRCGQRSIIFLINNGGYTIEVEIHDGPYNVIKNWDYVGLVNAIHNGEGRCWATRVRCEEELEAAIATATGDKADSLCFIEVVAHKDDTSKELLEWGSRVSAANSRPPNPQ
What are the official names of this protein?
Pyruvate decarboxylase 3, PDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: DAPF_PHOPR
Sequence: MQINFSKMHGLGNDFMVVDCVTQNVFFSPAAIRRLADRHRGIGFDQLLVVEPPYDPETDFHYRIFNADGSEVEQCGNGARCFARFVWMKGLTNKYQVAVSTKAGKMLLKLENDNQVTVNMGVPEFEPSKIPFRAKQTEKTYIMRVGERTIFCGTVSMGNPHCVTVVDDLELTDVDTLGPLIESHERFPERVNAGFMQVVSRNEVKLRVYERGAGETQACGSGACAAVAVGYLQGLLDENVKVSLPGGDLHISWAGEGKSLYMTGPVAHVFDGQIVL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_MAGSA
Sequence: MANPIEQFKIQPLVPLKVGSVDISFTNSSAMMVLSICLITLFLTLSVRSRALVPGRWQSMAEVFYEFIAGMLRDNVGQEGRKYFPFIFSLFMFVLFGNLLGMMPIPVIGFTYTSHVIVTFAMALVVFVGVTVIGFARHGTHYLRMFFPHGAPIATAVILIPIELISYFSRPFSLAVRLFANMTVGHIILKVMGGFVVSLGAFYLIPGAVPFAFLSAITVLEFGIALLQAYVFTILSCIYLHDAIHMH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPDL3_HUMAN
Sequence: MQKHYTVAWFLYSAPGVDPSPPCRSLGWKRKKEWSDESEEEPEKELAPEPEETWVVEMLCGLKMKLKQQRVSPILPEHHKDFNSQLAPGVDPSPPHRSFCWKRKREWWDESEESLEEEPRKVLAPEPEEIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEDPKQNIFYFLYGKTRSRIPLIALFQKLRFQFFCSMSGRAWVSREELEEIQAYDPEHWVWARDRARLS
What are the official names of this protein?
Putative speedy protein-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: CAP3_ADECR
Sequence: MRKRRTLTAPSHFNSMSAALNPMKMAAMQSQPTVDDSWAASISRIMSLTAGDRHKFSSQPFANRLDAILEAVVPSRKDPTHEKVLTIVNALIENGAIRRDEGAGVYDALLHRVSKYNSINTQSNLERLAGDVREAVAQQVRIAAGNLGSLTALNSFLARLPANVERGQDNYTGFLSALKLLVSEVPNTEVYQSGPHYFLQSSRNGTQTVNLTNAFENLKPLWGVKAPTMERLSISALLTPNTRLLLLLVSPFTDSVSISRDSYLGYLLTLYREALGRNHLDERTLEEVTEVSKAMGNENINNLQATLNFLLTNRQKKIPKDYSLTPEEERIVRFIQQAVSLRMMQENLSPTEALDVTAANMEPSFYANNRDFINKLMDYFHRAAAIAPDYFLGAVMNPRWLPPEGFFTGVFDFPERDNYIWDGLDSSLDLTRQDAMRFLEEKFIDDDQRTESRSVSRVPTPASSRRSSVAMASDSLIRPMNNDKNSLREIEVLADKLARWKTYKRESEEARESLPVIVRPKKYSSAISSDESDDGMSKPDKFLKFEGSGNPFAHLRPKLGRCL
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices.  Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets.  As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome.  During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3.
What are the official names of this protein?
Pre-hexon-linking protein IIIa, Capsid vertex-specific component IIIa, CVSC, Protein IIIa, pIIIa.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein IIIa family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Surrounds the border of each facet on the capsid exterior. Present in around 60 copies per virion.
Protein: LSPA_HELPJ
Sequence: MLNTTQKSLLVFMGVFFLIFGVDQAIKHAILEGFHYESLVIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMRQKELFKSHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKGIITLFK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IML1_NEUCR
Sequence: MASRNFSSGVPGHVRPPNWSSHLRQFSRNSLERIPDMPRSPDTVSSNSTIRDRPSSSSRRSRFERRWTVTVNESFARDEVLLNLDLIGDEATPGSLMAIDVFRPDAEKQAQGSHHHHHHHHHHHHKQPPPDRTKEAAESQQRYIFVVKDMPKELKARYPSVEVYVAKHIADVFGMRKGSQVTLTPIDHHNPAIEASHVELCFRDQYMSRSDMWQLAVRELSEKTVYKGQMVLFMGTLKAQVTAVYVEGRKVPSAFFGHNTKPIFRSESARYVLFIQMAREMWDFDSDGSGEIMFNKVVNGFLPALFKKWASLKVRHLVSIVLFARVEYDTGISTELGNPDVQNDYYTGVQSSGDRRPYKDFYRVVVSEMGSGEWTKILYQLKREFNYFRRDISTFHQKAMHSFSSSDDPADQQAALNRITAEASRAIYGNFLEAINMATSLFAHDYIDRDLMRTGISVVVISPSPGIFEVEYDALRRTTEALVGNGIGIDLICIPKAPLHSVPLFRYRNPEYSTEPTHHHKAKTAPSLSSTPKQTAPTIGSFNSMAGSYSPSRGTDITLHGDYAGSGLAQDEWNYALPQWLHVSYWTGESEEALSYHGIALSVSDVSKTRSGDDFLIRCRMYDLQMRSVMETNEIETKPLHLDPYFPHKALQANNVPKPFIDQDGNVFIQNLRIPETLFDHVYGFQKFAPDKHAKLGEKSLWKQLQDYDDSRARQPSFRHTLAPPSHIREYDDSVRRHHADDASLLGTSYTERRPSTSASQMTMTGHRSSQRFNADKPESRNRKTVDFDKLNSKRSPTITPKVPKFMKQISLGSSGFRIAAPKAATAELSIESVNADRSLASSRALMNAGTVATPAKAAINRSMSPQMFASGTPVFSPWGATPGSFAPSHQYFEGTPSRPMPIKSQQIPTDPAANMLSGSMLASTLRADYVPDNRDLFYSDAIRAEDAKKVYNNKLLAGAVPELPSTLSPTTALSPWLTLVNPSNPDSNKVDIATLYSRWQHVFPRPNETRVMKWKSLCSPAAVPLTTEYFPTKAQFESEYHRQPYNVSQNADDELAEEPKSRDEMLREMISLRFCQGFQVVVGPAVAKAFGQKQLKVTDIFSRDHTAEDGTSIFMSVGNTIHQLSCVNGTEIEVNIFVRKPIASAGLYNDRYLYKPAIRTLLDHGYKTRSYDMVAPTPDRNWNYVDAFVAGHNDELSEHLRFWRARFVLIPMTARHSFFPKTQYGDSEEEIRIEGIRKLAQMWQKHRYIPASERSFQASRRKKDMNPLDIVYKTEDPSVVIAAELETLPLLEGLEGGHRKGQLVTSREQFSKKNFSLAALAEAIQQPVENGGIRMQNRRWHLRLHYNCFIGSDMTTWLLENFEDLEDREEAEELGNRLMVTSDDKSKDESKDGRKDGGGLFVHVERRHPFRDGQYFYQISSDYAKPNPPGWFNTRRVPVSVPSTPHSEVRDSPRSNVSMSRPTSIHEDSSPTSGTVTPTAAMMAGGKKPRVVLSKVMKYDVDHRKRSYRPEVVDLHYDRLHNPDNCYHIRIDWMNVTAKLIEDAIEAWAREAALYGLRLVEVPINEACDITEINPFRRPYMIKLAVQPPNQQPITYFDPNSFTPQAQPGRHFYQRALLRKFDFVLDMEPASSFPYTVDVSYSWGKPDFKYTQFIHRSGTLIAEITDEGDILILANRLYSNRTAAQREKEMQQKGGGSGAGGDNLGLGPGPGRISTPGLYGPNAHPDQPNAVSSPLVKPTTAFLSPALRPHLIGPLASGPPSTNGFGTTGQPLNRSTVTVPVTPVIQDPEVIKDELESFCRDRSALEAFYRELLEREAHPPAPNTTPGLAPVKIPSTTATKDSTLAFATPHLGAGQNTTSTGHTVPDTNIPSLGLPPGVLAAIGGTGLSNLSDLQLVGSGTGLGISPVRVGSPSLLSAASAASAGHPSHSTMMRRASVQEGVMGSRIGLGFGGGASAAAAAAQAAAAAAAAGASGAGAAGSSSDAGGAGNIGGGAGGDAGASEH
What are the official names of this protein?
Vacuolar membrane-associated protein iml1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: ENGB_AROAE
Sequence: MPIFRNARFEVSIAKSGALPPPEGAEIAFAGRSNAGKSSAINTLADHTRLAFVSKTPGRTQLINFFRLDCGAVLVDLPGYGYAKVPENIRRQWQGLLEHYLRKRENLIGLVLIMDSRHPLTPLDRQMIDWFVPGGRPIHVLLTKCDKLSRNEAAATLASVRREVAALGPQISVQLFSSLKKIGMEEVEHKVAGWLGLPSDDLPAIPTPAQLRAAGK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RUVB_CHLPN
Sequence: MTHQVAVLHQDKKFDVSLRPKGLEEFYGQHHLKERLDLFLCAALQRGEVPGHCLFFGPPGLGKTSLAHIVAYTVGKGLVLASGPQLIKPSDLLGLLTSLQEGDVFFIDEIHRMGKVAEEYLYSAMEDFKVDITIDSGPGARSVRVDLAPFTLVGATTRSGMLSEPLRTRFAFSARLSYYSDQDLKEILVRSSHLLGIEADSSALLEIAKRSRGTPRLANHLLRWVRDFAQIREGNCINGDVAEKALAMLLIDDWGLNEIDIKLLTTIIDYYQGGPVGIKTLSVAVGEDIKTLEDVYEPFLILKGFIKKTPRGRMVTQLAYDHLKRHAKNLLSLGEGQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RSMJ_NEIMF
Sequence: MTDILIDNTATEAVRALIQAFSLVPVSQPPEQGSYLLAEHDTVSLRLVGEKSSVIVDFASGAAQYRRTKGGGELIAKAVNHTAHPTVWDATAGLGRDSFVLASLGLAVTAFEQHPAVACLLSDGIRRALLNPETQDTAARITLHFGNAAVQMPALVQTQGKPDIVYLDPMYPERRKSAAVKKEMTYFHRLVGEAQDEAALLHTARQTAKKRVVVKRPRLGEHLAGQAPAYQYTGKSTRFDVYLPYGTDKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAF1_SCHPO
Sequence: MLSKRGLNPVQAESRKKKKREQIKVREERAKRHEERLSHRNMSQMERQLSELTQLESSQALNAHDKQLLQNLQRDMAIMKKKNIHGHRVGRVESDKTKEAERQHKPRKPFIPKNPKRSIYYDPIFNPYGVPPPGMPYREKEELSSETDESVIDIPLPSEEYPFEDPKPREKKNKSFKPKHHKKQDINASSAQPKSTTTTEAAANTKDIEEETMIEYSAQPVVRDLRQEAAQFLPAAFQRQKLAKGQKIGQPDRDVSSQVQEDKDEEIDNFYKEIGGYL
What are the official names of this protein?
Protein saf1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DAPAT_DESAP
Sequence: MSFVEAKRIRNLPPYLFARIEQLIADKKAQGVDVISLGIGDPDVPTPDHIIEAAEKELKIPANHQYPSSAGMPAYRRAVADWYARRFGVELDPQREVVSLIGSKEGIAHLPWCFVDPGDVVLVPDPGYPVYAGGTILAGGIPHPVPLTAGNGFLPDLAAIPAETARRAKVMFINYPNNPTGAVASKEFFARVVDFAREYGILVCHDAAYSEIAFDGYRPPSFLEVAGAREVGIEFHSVSKTYNMTGWRAGWAAGNAGAVEALGRLKSNLDSGVFQVVQYAAIAALNGPQDGVQSLCEMYRERRDLVVDTLNDLGWRLTRPRATFYIWAPVPAGHDASSFAEMVLEKAGVVITPGTGYGTYGEGYFRISLTLPTPRLVEAMERLRGCLGRVTF
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: ECFA1_LISIN
Sequence: MAESFVRLEHVFYKYEDTEKYAVKDVSISAQKGEWVALVGHNGSGKSTIAKLLNGLLFPEDGLIKIGHFVLSEKNIWEIRRQVGMVFQNPDNQFVGATVQDDVAFGLENHGVPHDTMVERVESALNEVGMQSYALHEPARLSGGQKQRVAIAGVLALQPDVIILDEATSMLDPRGRAEVMETIRIMREQEDITVISITHDLDEVLFADRVIVMNNGEIHSEGTPKEIFEQADAMRAIGLGVPFIIELQEKLVAGGFETGSTVLSEGALLDQLWKLNSNN
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FOLD_SYNAS
Sequence: MAAIIIRGSDIAQEIREDLKKEAAWLKAYGVVPGLVTILVGQDPASMSYVTAKQKTACKLGFYSLQDSQPGHVSESLLLDRIARYNKDPRIHGILVQLPLPPHIDEQKILYAIDPGKDVDGFHPYNVGKLMIGQADFLPCTPAGIQQLLIRSGIQTDGAEVVVVGRSNIVGKPIANMLLQKQKGANATVTVCHTGTRDVGVHTRRADILIVAAGKPKAITADMVKEGAVVIDVGVNRVGVTSDGKAKLCGDVDFEPVREKAGAITPVPGGVGPMTITMLMVNTLKAARLSAGL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LCL2_NEUCR
Sequence: MRTLYLVLLSLLTLASPIAAQFGSFFDQMFGGHGHQQTQQQQQHQGHGHQQHPNVPSDPSIYQANYQRAHCDKYLCPDTLACVHYPHHCPCPWPLHEDKAELAEGQRICVSKGGFKAGEAARKIELARKGML
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: RISB_PYRNV
Sequence: MVRLALVVAEFNYDITSLMLQKAIEHARFLGAEVTYVVKVPGVYDIPMVLKDVVAKSDVDAVATLGAVIQGATKHDELVAQQAARKILDIAVEVDKPITLGIIGHGANRMQALERVEEYARRAVEAAVKLARRKKLLKDAKYSGATVYVE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: UPP_RHILO
Sequence: MKGVTVVDHPLVQHKLTIMRKKETSTAGFRRLLREISLLLGYEVTRNLELTTTTIETPIETMEAPTLEGKKLVFASVLRAGNGLLEGLLDLVPAARVAHIGLYRDHETLEAVEYFFKAPSDLADRLVIVVDPMLATANSAIAAIDKLKGRGATNIRFLCLLAAPEGIERFTKAHPDVPVFTASIDRQLNEKGYIMPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MAP1D_ARATH
Sequence: MAGVKSLQPRLISSFLGNNSIRSTQPLIHLFRFDLGRRHVSMQLSRTFSGLTDLLFNRRNEDEVIDGKRKRLRPGNVSPRRPVPGHITKPPYVDSLQAPGISSGLEVHDKKGIECMRASGILAARVRDYAGTLVKPGVTTDEIDEAVHNMIIENGAYPSPLGYGGFPKSVCTSVNECICHGIPDSRPLEDGDIINIDVTVYLNGYHGDTSATFFCGNVDEKAKKLVEVTKESLDKAISICGPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSVFHADPVVLHFRNNEAGRMVLNQTFTIEPMLTIGSRNPIMWDDNWTVVTEDASLSAQFEHTILITKDGAEILTKC
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 1D, chloroplastic/mitochondrial, MAP 1D, MetAP 1D, Peptidase M 1D.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: RL35_STRP7
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHLRKASMVHSGDYKRIKAMLTRLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SYE2_CAMJ8
Sequence: MHEKLTTRFAPSPTGYLHIGGLRTALYNYLYARKNGGNFLLRIEDTDLKRNSKEATKAIIEAFKWCGLEHDGEVTYQSERFDLYKEYVKKLLDEGKAYYCYMSKEELEELRAKQEAAKERPRYDGRYREFTGTPPQGIEPVVRIKAPQSGEIVFEDGVKGEVRFKAEDIMDDFIIARSDGTPTYNFTVVIDDALMGVSDVIRGDDHLSNTPKQIVLYEALGFKIPKFFHVAMIHGEDGKKLSKRHGATDVMEYKEMGILPQALLNFLVRLGWSHGDDEVFSLEDLKKLFDPYHINKSASCYNAKKLEWLNAHYIKTLPFEEINRQLKDLGFDLSVYEKAGFLLDLLRERAKTLHDIINGAKSIVNAPQNYDENAVQKFVNENNLELLQAFANTLKDQKTGKDFEDFTNDFLEKKEAKLKDLAQPIRIALTGSAVSPSIFEVLEFLGVDECKKRIDNFLKVRGK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_DROSE
Sequence: MMTNLFSVFDPSAIFNLSLNWLSTFLGILMIPSIYWLMPSRYNIVWNSILLTLHKEFKTLLGPSGHNGSTFIFISLFSLILFNNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMMYGWINHTQHMFAHLVPQGTPAVLMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYLLVTFLLTAQIALLVLESAVAMIQSYVFAVLSTLYSSEVN
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYF_CYCTA
Sequence: MRNINTYDWMKKWMTRSISILVMIHMITRTSISNAYPIFAQQGYENPREATGRIVCANCHLAKKPVNIEVPQSVLPDTVFEAVVQIPCDMQIKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEIKEKIGNLYFQNYRPNQKEILVIGPVPGQKYSEIVFPILSPNPATNKEVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNASTTGRVSKILRKEKGGYEITIDNASDGRQVVDIVPPGPELLISEGEFIKVDQPLTNNPNVGGFGQGDAEIVLQDPLRVQGLLLLLASVILAQIFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CWC22_DANRE
Sequence: MAAESNDSQKAMNLGPTLRDEPPSTEEIEQRQRKASTSSSEDGEHEDNDRRRVVGSPGSRDGSPRVGSPVARASPRAKRDQKSSDSDSDSSDSDDGVMRKIRSSVMHIRRTSDEETKNRERSSSPDRHEKKSKSRSRSRSRSRSRSRSRSPRERYRRARRSRERERDRYGDRERYERRSSRERDWEHRRRGRSASPDKNDKPPTEEPPVKKRKETLDPILTRTGGAYIPPAKLRMMQAQITDKSSLEYQRMSWEALKKSINGLINKVNVSNIANIIQELLQENIVRGRGLLARSILQAQAASPIFTHVYSAVVAIINSKFPQIGELILKRLILNFRKGYRRNDKQQCLTASKFVGHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAISFLKECGLKLTEVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAIRKDGFKDHPIIPEGLDLVEEEDQFTHMLPLEDEYNTEDILNVFKLDPNFLENEEKYKTIKREILDEGSSDSGDDAGGSGDDEDDDEEDEEAAAGEEQEKVTIFDQTEVNLVAFRRTIYLAIQSSLDFEECAHKLIKMDFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCLLKKEYMESFEAIFQEQYETIHRLETNKLRNVARIFAHLLYTDSVPWSVLECVRMSEDTTTSSSRIFVKILFQELCAYMGLPKLNERLKDTTLQPFFEGLFPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNAPKMIMTQNQEVESSDSSSSSSSSSDSSSSSGSSSESDSSESDSDSSSDSDSSSSSGSSSDSDSRRKKASGKKKDKSKSKKSSKAANQRSPLEERPTKRHENRRQDASKEDRRGSDKHNRDPQRRGQQDESPPARPRGEPERIRGQKEPHRHAQDHQDRPTDSGRHKDDGKNSRVNKDKDRRRSREKEPLRRSRDRSKSRERSRKEMDSRDSYGNGLERADKENRHSDRYKESRRKDDRRHR
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Promotes exon-junction complex (EJC) assembly.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22 homolog, Nucampholin homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.
Protein: SYFA_GEMAT
Sequence: MNLSEYLAQADALAAECHALLAGLDVATRLDVAKGQLNALKDDRLNALQSALRMLPAEDRRAAGGAFNTLKQSIQAALDAFGQRQSAASGVVQVDATMPARGIWRGSLHPVTLVIDEISEIFRELGFTIALGPEAETEWYNFGALNFPPDHPAMELHDTLYLGEDTLLRTHTSPVQVRTLQRYAPPVRVLAPGQVYRRDFFDATHAPAFMQLEGLAVDEGVSFVDLKATLAEFARRFYGATRRVRFGPSYFPFVEPGAQMDVEVDLGDGKGLRWVEILGCGMVHPNVIEAAGLDSEKYTGWAFGMGPARIAMSRYGINDIRVLYDSDVRFLEQFAR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR21_HUMAN
Sequence: MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILKLVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLISALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEPSPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIFDDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
What is the function of this protein?
Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B.  Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm.  Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning.  Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP).  N-APP binds TNFRSF21; this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).  Negatively regulates oligodendrocyte survival, maturation and myelination.  Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation.  Negatively regulates T-cell responses and the release of cytokines such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells.  Negatively regulates the production of IgG, IgM and IgM in response to antigens.  May inhibit the activation of JNK in response to T-cell stimulation.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 21, Death receptor 6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.