PharMolix/UniProtQA huggingface dataset:
Protein: KV6A6_MOUSE
Sequence: QIVLTQSPAIMSASPGQKVTMTCSASSSVSYMHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSATSYSLTITSMQAEDAATYYCQQWSSNPLTFGAGTKLELKR
What is the function of this protein?
Anti-2-phenyl oxazolone (PHOX) Antibody.
What are the official names of this protein?
Ig kappa chain V-VI region NQ2-17.4.1.
Protein: MNMG_CHRVO
Sequence: MIYPTSFDVIVVGGGHAGTEAALAAARMGCATLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMALATDIGGIQFRTLNASKGPAVRATRAQADRILYKAAIREMLENQPNLTLFQQPVDDLLIEGDRVVGAITAIGITFRAKTVVLTAGTFLSGKIHVGLENYTGGRAGDQAASTLGERLRELNLPVGRLKTGTPPRIDGRSVDFSVMEEQPGDTPEPVFSYRGKRAMHPKQLPCWITHTNERTHDIIRSGFDRSPMFTGVIEGVGPRYCPSIEDKINRFADKDSHQVFLEPEGLTTHEFYPNGISTSLPFDIQLAAVRSIRGMENAHILRPGYAIEYDYFDPRGLKASLETKAIQGLFFAGQINGTTGYEEAAAQGLLAGLNAGLFAREQEAWCPRRDEAYLGVLVDDLITKGVSEPYRMFTSRAEFRLQLREDNADLRLTEMGRKLGVVGDEQWDAFCRKRDAVEAEKARLQATWLHPSKLADPAALARVLGKPIEREYTLQDLLKRPNVPYRELMTVPEAADGAPELADEVAEQVEIQVKYQGYINRQNEELARRDNLEDIRLPGDIDYGLVKGLSKEVQQKLNQQRPETLGQASRIQGITPAAVALLMVHLRRGFTDAKTA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ACTP7
Sequence: MSFKFEAEVRSAQGKGASRRLRHNGQVPAIIYGGNAEPVSIILDHDKVNNAQAHDAFYNEVLTIVVAGKEEQVKVQAIQRHPTKPKLVHLDFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: SERC4_RAT
Sequence: MGAKDITGRSTTQGFAQQHGGVSDVVVKTPFYQVSCCGPVSWTSGCHSLTESTCSRLFYILLHMGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGNSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTSPRAQLHNSFWSLKLLFLLGLCTAAFCIPDEHLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCSWFLGVLLATLGFYSMAGVGAVLLFHHYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRLRQPNSGLLQASIISCYIMYLTFSALSSRPPETIIFQGQNHTLCLPGQNKMEPQIPDASVAVFSASIMYACVLFACNEASYLAQLFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQGSRARPADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAHHSESPPP
What is the function of this protein?
Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids.
What are the official names of this protein?
Serine incorporator 4.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNMG_HAHCH
Sequence: MDFPKSFDVIVIGGGHAGTEAALAAARMGSQTLLLTHNIETLGQMSCNPAIGGIGKSHLVKEVDALGGAMALATDRAGIQFRVLNSRKGPAVRATRAQADRALYKAAIREILENQPNLTIFQQAADDLIMQGDHVAGVVTQMGLRFHSKTVVLTTGTFLGGVIHIGLENHSGGRAGDPPSIALAKRLREMPFRVGRLKTGTPPRIDARSVDFSVMEAQPGDTPIPVMSFMGSVDLHPHQVNCFITRTNERTHEIIRGGMDRSPMYTGVIEGVGPRYCPSIEDKVNRFSDKDSHQVFIEPEGLSTHELYPNGISTSLPFDVQLQLVHSIQGMENAHITRPGYAIEYDFFNPQDLKHSLETKFVGSLFFAGQINGTTGYEEAAAQGLLAGMNAALRAQEKEAWSPRRDEAYIGVLVDDLITMGTREPYRMFTSRAEYRLLLREDNADLRLTEKGRELGMIDDERWRVFCEKREAIAREQQRLKSIWIQPATEKARKAAELLETELTREYSLHDLLKRPEMTWEKLSLLDADVAATPYEVAEQLEIQVKYAGYIDRQQEEIERLRRNENMALPADLDYSGIQGLSNEIKQKLTEVRPETLAQASRIPGVTPAAVSLLLVHLKKRGSLQRKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_STAAW
Sequence: MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PKHF2_DANRE
Sequence: MVDRLANSEANSKRIGVVEACFGTAGQPLAIPGRVLIGEGVLTKLCRKRPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVEDEGELRNGWLIKTPTKSFAVYAATATEKSEWMSHINKCVSDLLEKSGKSPTGEHAAVWVPDSEATVCMRCQKMKFTPVNRRHHCRKCGFVVCGPCSEKKFLLPSQSSKPVRVCEFCYKQLSTGATLPPRSDSYSRQGSDFGSNNISDDDDDDDSSD
What is the function of this protein?
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport.  Enhances cellular sensitivity to TNF-induced apoptosis.
What are the official names of this protein?
Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis.
Protein: DNLI_THEKO
Sequence: MRYSELADLYRRLEKTTLKTLKTKFVADFLKKTPDELLEIVPYLILGKVFPDWDERELGVGEKLLIKAVSMATGVPEKEIEDSVRDTGDLGESVALAIKKKKQKSFFSQPLTIKRVYDTFVKIAEAQGEGSQDRKMKYLANLFMDAEPEEGKYLARTVLGTMRTGVAEGILRDAIAEAFRVKPELVERAYMLTSDFGYVAKIAKLEGNEGLSKVRIQIGKPIRPMLAQNAASVKDALIEMGGEAAFEIKYDGARVQVHKDGDKVIVYSRRLENVTRSIPEVIEAIKAALKPEKAIVEGELVAVGENGRPRPFQYVLRRFRRKYNIDEMIEKIPLELNLFDVMFVDGESLIETKFIDRRNKLEEIVKESEKIKLAEQLITKKVEEAEAFYRRALELGHEGLMAKRLDSIYEPGNRGKKWLKIKPTMENLDLVIIGAEWGEGRRAHLLGSFLVAAYDPHSGEFLPVGKVGSGFTDEDLVEFTKMLKPYIVRQEGKFVEIEPKFVIEVTYQEIQKSPKYKSGFALRFPRYVALREDKSPEEADTIERVAELYELQERFKAKK
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Can also use NAD, but less efficiently than ATP.
What are the official names of this protein?
DNA ligase, Lig(Tk), Polydeoxyribonucleotide synthase [ATP/NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: AROC_MYCA9
Sequence: MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTMLGGVRHGLTLGGPVAIEVGNTEWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALGVDVISHVISIGDSDPYEGPVPDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISGQDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVALVVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSDEQPARRAANTAG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RRF_HAEIG
Sequence: MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGEGEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVDEVLADKEKELMDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y437_BUCAP
Sequence: MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRHIDATIAGFLSALMRYIIITFTLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAAGVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDGKIVVVPNNKIISGNIINYSREPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCWSSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN
What are the official names of this protein?
Uncharacterized MscS family protein BUsg_437.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATE_SULTO
Sequence: MTELDYSKIGLKVGLEIHQQLNTAHKLFCECPTTLHEEYHTQLERYLRPSFSELGEIDIAALFEWQKGKKYVYRVPPNSCLVECDEEPPHIIDEEALSIAVAVSLALHSTLVDEVYVMRKIVIDGSNTSGFQRTAIISLGGYIEDNGQRIGIQTIALEEDAARKITDSPTEIIYNLDRLGIPLIEISTAPDIKTPEQAERVALKIGQLLRLTGRVKRGIGTIRQDLNVSIQGGVKTEIKGVQLLELIPDIIKNEARRQYELLRIKEELQKRNLNKDIVKNSFKIVDLTEEFKDTNSKIIRKELEKNGRIYGLKIAGFKGIFGWQLMPNRRFGTEVADYVRALAGLGGLFHSDELPNYGITKEEVEKVRKILQINENDAFIIIVGPKEKLDIATNTILDRILYAFDGVPKETRAALDDGTTKFMRPQPGSARMYPETDIPPRRIDERILELSKQFVPEQPEIKLKKLIELGLSKDLANTMLNSLRLDLFEELVKKYSPKVSPTFIASTLEITVKYVKSKGGDISVITDNILEELIKYVYEDKISKDAVQEILLELATSKTQLNEIIKKYTPLNETELEKIIIETIEENKKEIENKKDKAFNIIMSKVMNKVRGRADSKKVIELIKKHLG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: SARZ_STAAS
Sequence: MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKK
What is the function of this protein?
Activates transcription of virulence factors alpha- and beta hemolysin genes (hla and hlb).  Also, activates RNAIII expression, a central regulator transcribed from the agr locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLU_CANGA
Sequence: MSQPSDIVKVIVALPTLSKKPQQGKKKKSKELEEITLQFRKDSKLQNVLDFLSIAPATKYFTNYNLKNSTGDLLLSSEEKTLRELCSDKDEYKVALELKPYNQYQALKHVLTSRDFFGFASETEDGLSNVAVSTGSKFYKLPLKEIKEKSPENEDKDTENKKPTSMNVTDEEKVEFNHMVHGLFETLKKEKKVLLKDLMNTDTSVVTPCLRSINFSPYNPVPAFYRTKGHLFYLQIVTLEGESLQVTAIPSGFYINKSTTSKFDPSPKENDGHVDTVHYTLYDLLASSSKNFVTHISSLEKKFDDLESVTYVRPACTTLNKPWLIPAIPTNGPDYLRTQIDSFNFEPERNFNDEFQSIKEIPTNTLQARIESERIFAKLTHEFTINATKGAMDILYGNGTAMNPDSPLEEQIFLKNNIFYSFVGDLNQTYADKGGDEAAIASANQDLRTLNMLTRLNLPNIHHLLTTIVDFGGKRILAQTPVPGLLSPMGVKITTNEETKEETVSELSSDICVKYGLDENEKKVVFNEEFDEILNDQFAKSFHLKKHTIQGTELVFSSQSKGIVGSDKRHYILDLANTYPLDVEFAKENFDDVKEASKKYPHRQTLIRPELVEKWWATKIENDKVELVKAYEENLYSYNPDAYQVPGVEDETVVEISKYLNEEIIPNVVQDYLNGNIISPYNGEHLADTFHKNGVNMRYLGKFANLVKEELRKQEEAHEAKLAQVIVDNKEYEEWEKSYLQKIETMIKERQAKINKLVQEGKEVPKELTEDLKLDDNEIKKPSTEKPVVVSYDELVPLIKTAELEIISRSLKHILRKYSRSLPPIVIPALISFVFNLLFGTTYNPAPAVESVDPLYPVDQYEFKNLTHDTLLKEIEQEAVVRYRYELEGDWFAEHELYPFTLIRSICNKFGVQLLNKDYFFSTEQLEEYKQSLDKKSRAKYVAPLTTFSVSDLTVIPKIKAIDYSSPISEELWSQGASIINENQKDGLTLLAQSIGFKEEVNSILHSSVAEKYLTLSTIYNKLGLNAEAIAFCRKSCAIYERVCGVDSFELLRALTNLATLEFANESPYNVALIYQRIIQTVSGYGLDKIHHPIFTNIFNYLEQLSLGVQDAKLAVEVLKSLGDFLVSIDGTESLPYAYIKSKLGNLLAADNRFSDALNQIKVAERIFTKELGTNHGSTAQARQWVDGLTNLIKDVNQKKQLQQDQTAASGLKQQPQKSKSGHNKKETTNPDLADKSVDELLSFIEGEDGKSSKTTKKSKSKGKNKK
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_BRASO
Sequence: MSFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGLDEGPKGSLTARMQEQTETAIALADALFFVIDARVGLTPADRAFADFARRADKPVLLLANKSEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALSKIVPPSDDEDDEREETDEERASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVLAVNKWDLMEAQPGQISALRRDADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWNRRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKARPPSFVLFCSRADAIPQSYLRYLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: THYX_MYCS2
Sequence: MAEIAPLRVQLIAKTEFMAPPGVPWETDADGGEALTEFAGRACYQSWSKPNPKTATNAGYISHIIDVGHFSVLEHASVSFYISGISRSATHELIRHRHFSYSQLSQRYVPEHDSEVVVPPGFEDDPELVEIFTSAVDASRATYTELLKRLEAKFADQPNAVLRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIACLRELVTVAPAVFSDFVISTLADGSEVATSPLATEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: Y2783_STAA8
Sequence: MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTLKLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNTRTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLKKEIENFKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSRSLEFTFVENKEENIYFTDSVQYTPSEDTRYESN
What are the official names of this protein?
Uncharacterized protein SAOUHSC_02783.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PSBT_PARMW
Sequence: MESFAYVLILTLAIATLFFAIAFRDPPKIGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DPMAB_METAN
Sequence: MNAADISRAPPGYLEVAWIADTCKLLMGLGWTTNYAGMIYKSLKDRTYGMALMPLCCNFAWELTYAVIYPFGSRQDKFTHYFGLMLNCGVMYTAVKNAEREWTHAPLVRRNLPFIFIICIAAWTTAHLALALQIGPSHAQAFSAYGCQLLLSVGALCQLLSRGSSRGASYFLWFCRFFGSLVLIPQDVLRYRYWRQDHEYMGSPLYIWFVSIFLLLDGSYALCLWYVRRFESEQEEAKKAKSI
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of the diterpenoid pyrones subglutinols A and B (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpmaA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Probable).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpmaD through the action of the prenyltransferase dpmaC to yield a linear alpha-pyrone diterpenoid (Probable).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpmaE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpmaB (Probable).  The dehydrogenase dpmaF is then involved in tetrahydrofuran (THF) ring formation at the C5 unit to complete the formation of subglutinols A and B (PubMed:32286350).
What are the official names of this protein?
Terpene cyclase dpmaB, Diterpenoid pyrone biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NNRE_PLAF7
Sequence: MITNLFIKSFTFSRSLKNFYVLSLLNYFKLKIYNKIYVPTLGVSLKRKRRSYSLNVRKMEITYLSQDLSQKIDNELMSDEVGYTTEQLMELAGLSISQIIFKEYKPCEFKKILICCGPGNNGGDGLVAARHLKQFGYNVVVLYPKVNDKTLFKRLLKLLEHYEINVLMSLRASDLDNYDLIIDSIFGFSFKGEPRKPFDEIIQMINNSNKVVVSVDVPSGINIDSGLSTNSLFINSDMNISLMLPKQGLKNYKKKHYLGGRFIPISIIKKYNLKVPCFSDDNPYVML
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: RS10_RHIME
Sequence: MNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NU6M_PONAB
Sequence: MTYALFLLSVILVMGFVGFSSKPSPIYGGLVLIISGAVGCAVILNCGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLVMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYVVIEIARGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSHR_CHABA
Sequence: MPMQEPQRRLLDPFNSTRTGTPHLKLSANQTGPWCLHVSIPDGLFLSLGLVSLVENVLVVISIAKNRNLHSPMYYFICCLALSDLLVSVSIVLETTLILVLEAGALATRVTVVQQLDNVIDVLICGSMVSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARWAIVAIWVASISSSTLFVAYYNHTAVLLCLVTFFLATLALMAVLYVHMLARAHQHAQAIAQLHKRQHLVHQGFRLKGAATLTILLGIFFLCWGPFFLYLTLIVLCPKHPTCSCFFKNLNLFLALIIFNSIVDPLIYAFRSQELRMTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_SHEWM
Sequence: MAKSKGNREKIKLVSSAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVMYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRPB_XANAC
Sequence: MSAQPISDFYAYPDAAGHFGQFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLKHYVGRPSPIYHAERLSREVGGAQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRMKLLGATVIPVTSGSATLKDALNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISACVGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICDDDGQITETHSISAGLDYPGVGPEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAALESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAAREGIAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TRUB_DECAR
Sequence: MQFKRAWKQVDGVLLLDKPLGMTSNDALQKARRLFSAAKGGHTGTLDPLATGLLPLCFGEATKFSADLLDADKTYEAVLKLGVTTDSGDAEGQVTSTAMVDIQKEQVSEVLPRFVGDIQQIPPMHSALKRNGRPLYELARQGIEVEREPRAVTIFAIDCLDFSGDLLTLRVACSKGTYIRVLAADIGKALGCGAHLAALRRIVVGDIRLGNSVTLAELETLDEAGRMERLLPVDALLQSLPIVGVEGPEAERFRHGNPVSLPAGLAGKARVYAEGRLIGVGEPGHGGLLWPKRLVQLAD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: AP2D_MOUSE
Sequence: MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
What are the official names of this protein?
Transcription factor AP-2-delta, AP2-delta, Activating enhancer-binding protein 2-delta.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THSB2_BACCS
Sequence: MTLFTENDLLNNSYKSIQKSYHFSENQAAKNILEQAYKNYDKNKIYDIFLSHSFLDARKILGLKNYIEGLGYSVYVDWIEDKQLDRSKVSKETAGILRERMQSCKSLFFAISENSDHSLWMPWELGYFDGIKQKVAILPVLKSSYDDSYNGQEYLGLYPYVAKGTIINSTQEEIWIHSSQKQYVRFRNWLQQN
What is the function of this protein?
TIR-like domain-containing component of the Thoeris antiviral defense system, composed of ThsA and ThsB and ThsB' (Probable).  In the presence of NAD(+) produces a signaling molecule that activates cognate ThsA (AC J8G6Z1) to hydrolyze NAD(+) (PubMed:36174646).  The signaling molecule is a cyclic ADP-D-ribose isomer and may be 3' cyclic ADP-D-ribose (3'cADPR); it is not 2'cADPR (Probable).
What are the official names of this protein?
Probable 3' cyclic ADP-D-ribose synthase ThsB', 3'cADPR synthase ThsB', Thoeris protein ThsB'.
Protein: PYRK_BACCQ
Sequence: MMQKQNMIVVNQKEIAKNIYELVLQGTLVQQMNEPGQFVHIKVAEGIAPLLRRPISICNVDQEKNEFTMLYRAEGQGTKTLATRKQGEMVDVLGPLGHGFPVEEAEAGQTALLVGGGIGVSPLYELSQRLVAKGVRVIHILGFQTKDVVFYEEKFAELGDTYVATVDGTHGTKGFVTDVIDHYGIDFDILYSCGPLAMLRALEGRYKEKKAYISLEERMGCGIGACFACVCHLQEDPSGHSYKKVCSDGPVFPIGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.