Protein: EQXS_GIBF5
Sequence: MSDNEPIAIIGSACRFPGDSSSPSKLWDLLKSPRDLLTKVPPNRYNADAFYHADSKHHGTTNVRHSYFLNEDPARFDNNFFNIQPGEAEAIDPQQRLLMEVVYQGLCASGQTIEGLRGSPTAVYVGVMCDDWSGIITRDLEVFPQYGATGMARSIMSNRISYFFDWHGPSMTIDTACSSSLVAVHQAIQTLRSGESEVAIAAGANLILTPGRSKMWDQDVNGYARGEGIAAVVLKPLSAAIRDNDHIDCIIRATGVNQDGRTPGLTMPSATAQADLIRSTYARAGLDINKPEDRPQFFHAHGTGTPAGDPREAEAIYRAFYSDVKDDKLYVGSIKTVLGHTEGTAGLASLIGTALAIQNKTIPPNMHFDVLNPKIKPFYDNLEVPTKAIAWPETHKGQPRRASINSFGFGGTNAHAIIEAYEPATTDSAPGPLFSPLTFSASSEPSLRSLLSSYSDHLKSNPDLSLKDLAYTLQTRRSTLAYRVAITASDVEDAYTQLDTIGNGEQSSTIGVRQVTKASPKIMGVLTGQGAQWPRMGARLVEESAFASQRLFELDEALSSLPKDDRPSWTLREMILADSKSSRIAEAAISQPLCTAVQVVLVDLLRQAGVELSSVVGHSSGEIGAAYAAGLLTARDAIRVAYYRGLYAKLAQSPNGRKGAMMAVGTTFDDASEFCELDAFQGRIQVAARNSSSSITLSGDEDAIVEAIETFKDEGKFARQLKVDTAYHSAHVLPCAKPYLDAMERCQIESANPTSTKWYSSVHDGQAMTAELLTPQYWVDNMTSAVLFSPAVEHAWREGGPYDVIIEVGPHPVLKTPCLDTLEDMTGDRPPYSGVLGREKDDIQQFASGLGFIWTQLGAGSATFERFEKVASDSKSIPSFIHDLPNYPFDHARQFMSMSRVSGWYNSMQEAPHPILGRRCHDRETSQTIQWRNVLNPKEIPWLHGHQIQGQIIFPATGYISMAIEAVNIIAGSDLGLVTIEDLRIGRALAFSDDDASVESMFDLRIISRSEKEIEAEFSCYSGLPQNHTTSMVLNATAHVKASLSVPTAQKLPNLKIDDFNLRKVEVDRFYDFLGRLGYNYSWPFHGTTSIRRKANYATGTLEDQSGSEWEDQLLVHPGMLDTSLQTTFAAFCCPGDERMWALHLPTSFRSIVVNPYFTSAGIGKQKSFQYQSVAIQERKASKVIVELNLLSEETGDTFLQIEGMELVPFSPATPENDAVLFSRFDYRLASPDGELTAAEYSFRDEDYKMALDSERIAFYYLRRLVETITPEDKANTLPHYRHLVEWAAHVVPQVIDGRNPHIPSSAQKDTHEDIQNILKKHYERVDVRLLESVGENLPQVIRENGNILEHMTKDGMLDDVYEEGFGLDLVNKYIAHMTAQIAHRYPRMNILEIGAGTGGSTREILPRLGSAFSTYTYTDVSGGFFDTAQDRFKDYAERMIFKTFDMNISPGSQGFTEGTYDLVIASNVLHATLELEDMMKHVRSFLKPGGFLIILETVNNDCLRVGLPMGSLPGWWLGAEHGRRWGPTLTLPQWDSLLWKCGFGGIDTTTPPVHKILPGHVFCAQALDDRVEILRSPLSHLSDLPETKSTELVIVGGETLKVHRMCEQISRRLKPKYASIARFNSIEELNTSGLADSCAVVSLTELDEPLFANMTSDKLDALKTLWKQGGSILWVTSGARDENPYSYMTTGVGRCMRFEYPNITLQALDIKAMTDRTPGLVAEHLLRLELLDKWSKELRPEELLWSLEPEIYVDDDTTIVPRLYPYESGNARYNAERRNIVEDADLQTDRVIFVENEGKWEVQHASPLHIPQELPFASKMKTIRITHFSPATINFAPGVSLMVCAGIDAASGERLLAVTHVAESPISVPADWCIPLGELDGVDTLANVSAFLIASSILKHVATEETLVVHGAPSRLASALEGLAKESSITVFLTTSERANKNGWQYIDSHLPERVIKASIPRSATKFINLSQDANMGETGRAISACLPRYCEVINTERLFIWGKLIRESVSKEDISIVFNRAFYETKSLSSTATDARLISLQDVSGVSAAEVRFAVVDCIDSSVKASIRPIDDGRIFQADKTFLLIGLSGELGQSLGKWMVEQGARNIVLTSRRPNVSQHFLDEMATMGATVKALPMDVTNRDSLHACVDTIQKTLPPIAGVVNGAMVLRDALFENMPYEDFMKVLSPKVLGSQLLDELFYDTPLDFFIFFSSTTAVMGNSGQSNYIAGNMFMNALAAQRKKRGVAASSIDISSIIGLGYVERAEDLSEDTFIKMGYKPMSEQDLQKLFAEAIVLGRPECDEVCELVTGVTPIYTDAQASDQYLKDVKFGHFLMERLDTQAYTGKTSTVPVRVQLADVKTKADAVAIIKGMFSLLTPVIIADLERFLHFEQGVDSLMAVEVRSWFIKELDIDIPVLKILGGMSVPDLIEESLNLISDSILDVSSLEAGSTPTTQPPKPTLQIARVTPPESSHGTSDDSKQQTGSDSSRSPIDTPLTSMEIQEPAKAEDSTDNSTPLKTFPNELSSIMSYGQAGFWFLNDYLVNKRAFNMAVMLKLTGQVRVQALEKAVNLVAERHEVLRTRFFWGDDGDERTPLQGINPADLKLTTKKVADESEAGMELKKLHDEEWDLSRGEGVKITLLSLSDNVHFLLLGMHHIYIDGYSFSVFFKDLEVAYTKNTLPSLPVESQYRSFALQQRQMYANGNLTKSIEYYRRSFPKEFSPIQLFPFALTPARQFANDYSQHEAKMSIDPELAPKVRQLARVNRSTSFHVYLAALELLLFTLLPNIEEVFIGIADANRGDKKFMGSLGFFLNLLPLRFRRKRRGTQLSSIIQTARDTAYGALQHSQLPFDVLLRELNVPRSDKYTPIFQVFMDYRQVVQERSSWGGCKLHGEKWHNAGTGYDIALEVNENITTDTLLGLRLQKQLYSEEHTALLLRSYLSVLEYMVQGTNKAADTVPPWSKDDIQVALDAGKAPEFQPKWQSTISHHIDQTIQANSTKVALKDGNGTVLTYEQMGNRVNSITQALIDAGTTQGTVVGVFQEPSSDWICSLLAIFKAGAVYVPLDLRNSIPRLASIVKASRPSLIITDHTTDDKVELIGAKYITQLQLSKVVDQEFKEPNRAKVGSLAVILFTSGSTGEPKGLMMTHTNLMSYAEVSSKTFSKPDESLMVLQQSPFSFDFSLDQTVAALANGGCLCIVPASKRGDPDEISKIMVKEGVTYTTATPSEYDLWLRYSTSTLRQCTSWKYAFSGGEAMSHKLAREFGTLSLKNLHVFNGYGPAETTILSHRIDLQYTDPDLPDPLPAGCPMPGFSVCIVDEKMRPVPLGVQGEIVLGGPCIVSGYLSMPDATKDKFLPDTFFGTSGKVYRSGDRGRLCHDGLLFCDGRLEDSNMIKLRGFRVELDEVEKTIISHSAGTLSHAVVTLRGTEEGRYLAAHVVFAPEFPEQNRESIMKTLRQTLPLPPYMRPSVFQILADIPRTAHLKVDRKAIQEMPVQISASHDSGTLTVAEQRLSELWRRVLPLDPGSLSPESDFFLIGGNSILLVKLQALLRQTFKTAPKLVALMGASTLGTMAVVLESCGSVGVIDWDQETALPNGLQGAVALRPVNKITDITVLLTGSAGYLGRHLVPALVEDPRVTRVHCLVRSVNNEKLSTSSSSKVRVIESDLSKPGLGLSASTYSRLAEETDVIIHSAANRSFWDRYEVLKPDNLDSVKELVRFAASSGRSIPLHFLSSGAVKIYDGDVVTPPTDGSDGYVATKWASETFLRNAAGSIGLPVYAHRPTVSSKAQTKTDQASIVDELFSIVKFLGVRPSFEGVTGSVDVLPTGDIVKAIQDSVLSSSAGGEGYNVLQHEAHQRAFVEDFAGVVRADDSLNKLPSISILDWFGKAKKAGFSYFLASQNLVMGEGEGHLVSRR
What is the function of this protein?
Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of trichosetin, a trans-fused decalin-containing tetramic acid with antimicrobial activity (PubMed:28379186).  The PKS module of PKS-NRPS1 together with the enoylreductase (ER) catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the PKS-NRPS1 NRPS module (By similarity).  Activity of the Dieckmann cyclase domain (RED) results in release of the Dieckmann product intermediate (By similarity).  Diels-Alderase (DA) is involved in endo-selective Diels-Alder cycloaddition to form the decalin ring, leading to the production of N-desmethylequisetin also called trichosetin (By similarity).  The cluster does not contain the equisetin N-methyltransferase and consequently, trichosetin is isolated as final product (PubMed:28379186).
What are the official names of this protein?
Trichosetin synthetase PKS-NRPS1, Hybrid PKS-NRPS synthetase 1, Trichosetin biosynthesis cluster protein PKS-NRPS1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NRP synthetase family.