PharMolix/UniProtQA huggingface dataset:
Protein: VELB_LACBS
Sequence: MIQHTNARQSSVAIAPLRQLVSDSPEQWGYWLGRKHYSLEVVQHPLRARMCGFGDKDRRPLAPAAVAKMVVRRDDNSIVDVDDMDCSFFLVTVDLWSEDGKHETNLVLHPSSVDRHIPPHSSTKSRRRGTSSSAPQSRAPANQTPSGGSTPTLSQHRPGEQRPPLPHPHASGYNNQGYVTPHAPQVNDALGFPPSTPYGPTQADSSWGYPPPPPGDRSTSFPHPTLPSIHTLGRSPSSSTSDHWNSEPEPQSLPYGAWNTDAPYHPSISSYSNSQVDPSVRNHSNSEGIENPGWSSSEATSPHSQADHAAYESSTYHHSAYHPAPTHSQMAPGTCSSQHVSTVPPPPRHTYTRTLVGPLSANACRLLDEHRKPGIFFLFQDLSVRTEGTFRLRMRLMNVGAPPAPEVGAARVHNDVSPVLAQTFTEQFTVYSAKRFPGVPDTTALSIALGNQGQKLPLASDGLSEALVEESSRVQQASETQWFRV
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity).  The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity).  Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The velB-VosA complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).
What are the official names of this protein?
Velvet complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear localization is mediated by veA (By similarity).
Protein: NUSB_ANASK
Sequence: MTSRRTRARERALQALYQIDVAAEGIDDALSRFWKSFEPVEREVMDLAEGLVRGVAQHRRAVDEAIEAVSTNWRLDRMAKVDRNVLRLAVFELLRTDVPVKVVINEAIELGKKYGSESSGAFVNGVLDKVASGLPPARRGER
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MNHD2_STAAW
Sequence: MLSNLLILPMLLPFLCALILVFLKNNDRISKYLYLGTMTITTIISLMLLIYVQRHRPITLDFGGWSAPFGIQFLGDSLSLIMVTTASFVITLIMAYGFGRGEHKANRYHLPSFILFLSVGVIGSFLTSDLFNLYVMFEIMLLASFVLITLGQSVEQLRAAIIYVVLNIIGSWLFLLGIGLLYKTVGTLNFSHIAMRLNDMGDNRTVTMISLIFLVAFSAKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDQHNDLIHPLLATMAAITMVIGAIGVIAYKDIKKIAAYQVIISIGFIILGLGTNTFAGINGAIFYLVNDIVVKTLLFFIIGSLVYITGYRQYQYLNGLAKKEPLFGVAFIIMIFAIGGVPPFSGFPGKVLIFQGALQNGNYIGLALMIITSLIAMYSLFRILFYMYFGDKDGEEVNFKKIPLYRKRILSILVVVVIAIGIAAPVVLNVTSDATELNTSDQLYQKLVNPHLKGED
What are the official names of this protein?
Putative antiporter subunit mnhD2, Mrp complex subunit D2, Putative NADH-ubiquinone oxidoreductase subunit mnhD2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OMP1_ACTEU
Sequence: VTVYDAEGTKVQLDGSIRLVM
What is the function of this protein?
Structural rigidity of the outer membrane of elementary bodies and porin forming, permitting diffusion of solutes through the intracellular reticulate body membrane.
What are the official names of this protein?
Major outer membrane protein, MOMP.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ERF98_ARATH
Sequence: MESSNRSSNNQSQDDKQARFRGVRRRPWGKFAAEIRDPSRNGARLWLGTFETAEEAARAYDRAAFNLRGHLAILNFPNEYYPRMDDYSLRPPYASSSSSSSSGSTSTNVSRQNQREVFEFEYLDDKVLEELLDSEERKR
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF098.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_ECO7I
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RXLRX_PHYIT
Sequence: MRMHSVLMMVVATLAIANGSVSAAGGSNLRKAKATSSINSFNTVQTEAKNSRMLRNTDVATGENGHVYYYPAKKGERKPFIEVRLKKALSNSKKVNRLYEDWYKSGFSTKKVAKELNQSENRELKETYKTLAIGYTAFVKGKQSQQQLQ
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_18609.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus, host nucleolus. Host nucleus. Host cytoplasm.
Protein: CSPA_AERSA
Sequence: EKGFGFISPADGSKDVFVHFSAIQSTSFKTLDEGQRVEFTIEQGQK
What are the official names of this protein?
Major cold-shock protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB4W_CHATY
Sequence: FLSLIPGAISAIASLFK
What are the official names of this protein?
Peptide Ctry2801.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CPSY_MYCTO
Sequence: MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRKVLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTIDEPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVYEETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVVFDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYALRSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYNSHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKTRIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLIEMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVLYVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLERYFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA
What are the official names of this protein?
Exopolysaccharide phosphotransferase CpsY, Stealth protein CpsY.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: COAX_CALS4
Sequence: MLLAFDVGNTNIVMGVFKGKKLLHSFRISTDKNKTYDEYGMLVNQLIGYNGISLTEIDDVIISSVVPPLMNTLQVMSLKYFRTKPIVVGPGIKTGINIKYDNPKEVGADRIVNAVAAYELYGGPVIVIDFGTATTFCAISEKGEYLGGIIAPGLMISADALFQRTAKLPKIDLTKPPTVINRNTVASMQSGIIYGHVGMVDYIVTRMKGEFAPSAYVVATGGFANMIAEESKTIDTVNEMLTLEGLRIIYERNKE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5639_DICDI
Sequence: MELVKCQPGICNCSCKPESLIPTTTSTSTTTTSTTTSTTTSTTTTTTTTTTKDFNTET
What are the official names of this protein?
Putative uncharacterized protein DDB_G0283705.
Protein: TREF_ECO8A
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKMIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWZA_BACSU
Sequence: MSFLISLIVAIIIGWLGSLFVKGDMPGGIIGSMIAGLIGAWIGHGLLGTWGPHLAGFAIIPAVIGAAIVVFLVSLLTRKRG
What are the official names of this protein?
UPF0410 protein YwzA.
What is the protein family that this protein belongs to?
Belongs to the UPF0410 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH3_STRPG
Sequence: MNTLVLKIDTILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_YERE8
Sequence: MSLLPVMVIFGLSFPPIFLELILSLALFFVLRRVLQPTGIYEFVWHPALFNTALYGCLFYLISRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAT_ECOLC
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGEEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: SYFB_STRMU
Sequence: MLVSYKWLKELVDIDVPSHELAEKMSTTGIEVEGVDVPAEGLSKLVVGHVLSCEDVPETHLHLCQVDTGEEESRQIVCGAPNITAGIKVIVALPGARIADNYKIKKGKIRGMESLGMICSLQELGLPDSIIPKEYSDGIQILPEDAVPGESIFPYLDLDDEIIELSITPNRADALSMRGVAHEVAAIYDKSVHFEDKVLTESDKKAADLIKVAIASDKVLTYKARVVENVTIKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDLDKFEGKDILARQAKAGEKLVTLDGEARDLIEEDLVITVADKPVALAGVMGGAATEIDASSKNVVLEAAVFDGKSVRKTSSRLNLRSESSSRFEKGVNYADVVKALDFAAAMLTELADGTVLAGQVSAGAVPTDDIQVSTSLDYVNVRLGTDLVFSDIESVFARLGFGLSGNDEKFTVSVPRRRWDISIQADLVEEIARIYGYDKLPTTLPEAAGTVGELTKTQKLRRKIRNLAEGSGLSEIISYALTTPEKAVAFTPNPTKITELMWPMTVDRSALRQNIVSGMLDTIAYNVARKSNNLALYEIGKVFEQTADPKKDLPKEIDTFAFALTGLVTEKDFQTAATPVDFFYAKGVLEAILAKLEITVQFVATKEMANMHPGRTALIERDGQVIGYLGQVHPQTAKLYDIPETYVAEVNLNALEAALKSDLVFEDITKFPAVSRDIALLLSEKVSHQDILDAIAASGVKRLIKVKLFDVYAGEKLGVGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITSALTEKVGAEVR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_LEGPC
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTQDAQVVVRYQGGHNAGHTLKINGVKTVLRLIPSGMLRPNVTCYIANGVVLSPQALLSEIKELEGNGVNVRERLRISLACPLILPYHIALDKARETHMGKSAIGTTGRGIGPAYEDKVARRALRVGDLFHRDRFANKLTELLDYHNFVLTQYFKQPAVDLESLLDESLQWVEELRPMVCDVSACLHEHRKQGENILFEGAQGVYLDIDHGTYPYVTSSNTCVGSVINGAGFGPRYIDYVLGITKAYTTRVGGGPFPTELLDDVGKRIAERGQEFGAVTGRPRRCGWFDAVLLKRSIELNSISGLCVTKLDVLDGLEVLRIAVAYKDRDGNILSRPPLAADDFNDLLPVYEELPGWQESTADVTLMSDLPANARAYLKRIEEILGIPIDMLSTGPERDSTITLRGPFL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_ECO24
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THTM_SCHPO
Sequence: MFSVGKKISFILPIKGVLQKLKDNAQKTVLLDATWYLPTDTKNGKKEYLESRLPGAQYFDIDEAKDHKNPLPHMLPPADEFASYVGKLGIDRNTNVIIYDRKGFFSSPRVFWTFKVFGHEHVFLFPNAFNAWKTEGLELETGEPRTPKPVVYEGAKLNKDLVASFDDIVKVIESPDAAGVHIVDARAHERFLGNVPESRPGLASGHIPTSINIPFTETTAAGITAPKPEEDLEKVFSSHGLTDKSVPIITSCGSGVTASVLFAALKECGFKDVRVYDESWSGYGKRANEDSSLLATGP
What is the function of this protein?
Required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs.
What are the official names of this protein?
Probable 3-mercaptopyruvate sulfurtransferase, MST.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DPH3_HUMAN
Sequence: MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQFVCGETVPAPSANKELVKC
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase.  Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3, CSL-type zinc finger-containing protein 2, DelGEF-interacting protein 1, DelGIP1.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YTXG_BACSU
Sequence: MIIILYLSVALIAVAFLVLVIYLSKTLKSLQLTLKNVASTLEGLEGQMKGITTETAELLHKTNRLAEDIQEKSEKLNTVVHAVQGVGASVQQFNTSMKQAAGSVSASVRENQDKINQVVTWSQAAMEIWEKWKQKKKSAL
What are the official names of this protein?
UPF0478 protein YtxG.
What is the protein family that this protein belongs to?
Belongs to the UPF0478 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: WDR82_DROME
Sequence: MKIKLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEGL
What is the function of this protein?
Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 (PubMed:21694722, PubMed:21875999).  Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome (PubMed:26577379).
What are the official names of this protein?
WD repeat-containing protein 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SWD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_BORBZ
Sequence: MLKAVLETTIGSKSKRDLKDYLPTLRNINKLERWALLLADEDFSKETEKLKDELKSGNSLENILERAFTLSREAARRRLKERPYDVQIIAGLALHKGKIIEMKTGEGKTLSSVQAAYLNSLTGDGVIIVTVNDYLAERDSNWMKPVFDLLGVSVGVVLSNMDYELRKAQYAKDITYVTNNELGFDYLRDNMRYDLNEKSLRKFNYCIIDEIDSILIDEARTPLIISGPTEGNTNAYLEVNSLVSFLKECSKDPKTGDYPLEIDDLDGDYTVDEKAKRISFTAKGLNNLEQLLVSKGIISGSMYTDSNFNYVHYMTQALKAHLLFLKNREYIVGDSGVEIVDEFTGRVLTGRRYSDGLHQAIEAKEGVRVANENKTMATITFQNLFRMFDKISGMTGTADTEAKEFHKIYNLDVVVVPTNRLLARIDEDDTIYYTEEFKFNAITDEVYKTYKKGQPVLVGTVSIEKSEILSAMFKSRGIKHEVLNAKNHSREAFIIAEAGAKHAVTIATNMAGRGTDIKLGGNIEHRVRKKIGTNVSLEEFQEAVKNERENYLKDYNEVKSLGGLYVIGSERHESRRIDNQLRGRSGRQGDPGRSRFYVSLEDDLMRLFAGDNLRSLMGKLGMATGEPITHSLLTKSLINAQKRVEDRNFEIRKHLLEYDDVITKQRDFIYAQRNSILKDTAIKDRILVALEEYLSFLLEGTKSSTVSNVFLNEVNSIFAYMLESLGSIENISYLDLKAKLMQIAKANLDEKENLIGRDLFNGFLRYEYLKNIDFKFQEHLANLDSLREAVYLRSYANKNPITEYKEEGFSIFSELIKDIKVSTIRRVLQLKLDSNSSDFKSTKKSRNVKPIHKELSGIVINENKSASNVQVVRSSPKIGRNEPCYCGSGKKYKNCHGKS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: FADR_SHEB9
Sequence: MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYNPDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYFTSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_SALEP
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPRYADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPGVRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVRNKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALAEAAEHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANF_SHEEP
Sequence: MGSSAITTSFLLFVAFQLPGQTGANPVYGSVSNADLMDFKNLLDRLEDKMPLEDEAVPSQVLSEQNEEAGAPLSPLSEVPPWDGGRSTQPREMGAPSDGDPGNPPRSVLLKSKLRALLTAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRYRR
What is the function of this protein?
May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation.  In vivo promotes natriuresis.  In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
What are the official names of this protein?
Natriuretic peptides A, Atrial natriuretic factor prohormone, preproANF, proANF, Atrial natriuretic peptide prohormone, preproANP, proANP, Atriopeptigen, Cardiodilatin, CDD, preproCDD-ANF.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
[Long-acting natriuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Vessel dilator]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Kaliuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Urodilatin]: Secreted. Note=Detected in urine. Not detected in blood. Increased electrolytes, osmolality and intracellular cAMP levels increase peptide secretion/excretion. SUBCELLULAR LOCATION: [Atrial natriuretic peptide]: Secreted. Perikaryon. Cell projection. Note=Detected in blood. Detected in urine in one study. However, in another study, was not detected in urine. Detected in cytoplasmic bodies and neuronal processes of pyramidal neurons (layers II-VI) (By similarity). Increased secretion in response to the vasopressin AVP (By similarity). Likely to be secreted in response to an increase in atrial pressure or atrial stretch. In kidney cells, secretion increases in response to activated guanylyl cyclases and increased intracellular cAMP levels. Plasma levels increase 15 minutes after a high-salt meal, and decrease back to normal plasma levels 1 hr later (By similarity). SUBCELLULAR LOCATION: [Atriopeptin-3]: Secreted. Note=Detected in blood. Slight increase in secretion in response to the vasopressin AVP.
Protein: NNRD_HETP5
Sequence: MFCIIHFGNPKNDKFLGSSTLYSQKLKTNNIKILCLQVFYYNIYESTNNNNNNKNKNKTLLLNNIRTYSTLSKGALSTTTTATTKKMSMDDSFELPTNLNHFLSYVPSLEYHMHKGQCGRIGVFGGSAEYTGAPFFAGITSLRLGADIVHIFAPSEGGTATAIKTLSPELIVHPLDQQMDPSTIIPWLLSIHVLIIGPGLGRSSIAWKSAKEVIKAARNINLPMVLDGDALRLICEDLELVKGYDKVILTPNFVEYRALSDAAKKLNNDNSNNILSPSDLAKALGNVVIVQKGQEDIITDGTISYSCDKAGMPRRCGGQGDVLAGVIGTFYAWTQNALKGKTSEELEHLKESIGENQSAAASAAYAGCVLVRYAAKLAFKNNRRSTITDDIIKSVPNALVWGFLTDDRGRPTI
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.