PharMolix/UniProtQA huggingface dataset:
Protein: SERC_BLOFL
Sequence: MKKIFNFSAGPSMLPKQVLNQIQQELYDWNNLGISIMEISHRSLEFMELVHDTKRNLRNLLNIPNSYEILFCHGGARAQFSAIPMNFLRGSADNIDYINTGYWGYLAAIESKKYCHPNIINISSSKNELRYIKPMSEWNISKNSTYIHYCPNETVEGISIDDIPDCFEKKIVIADFSSTLLSRPVNVNNFGMIYAAAQKNMGISGLTVLIIRRSLINNISTVQKIPAILNYRILADSNSMFNTPVTVSWYIANLVFKWLQDQGGLDKIAEYNKKKSNLLYHAIDSNDFYYNNIHSLNRSRMNIPFFLKKEKLNSLFLSESTSFGLHGLKGHKVIGGMRASLYNAMTLEGVQKLVNFMNFFSKKYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_SYNAS
Sequence: MFKEFKEFALKGNVVDMAVGIILGVAFGAIVKSLVDDLLMPGIGILLGSADFSNLFLVIKEGATPGPFTTLADAQKAGAVTINYGLFINTIVNFIIVAFALFLVIRNINQLRRMTEKPPVEEAPTTKDCPYCLSAIPLKATRCPNCTSELKG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LCPS_ASPNC
Sequence: MNQNGTRLCYSVREVPPTSFVSAPANYKRASSHCTYTIPAASALTVLYYPFFTAQDRCKICILITIAILATLPWDSYLIRSAIWTYPPDAVVGLKILDIPIEEVFFFAIQTYITSLTYCIFTKPLVRPMYLRSHLERRGTRYVVATVILALMGGGTACLLLGRRMTYLGLILVWACPILLFQWMMSYPFLSELPWKPTITSICLPTLHLWFADSRAMGTGTWRIEEGTKLNFRIGGLELEEALFFLVSNMMVVLGLVGCDYAYALQEYESLSQPASDVYITLRKALSLLARPLPIDASLISALSQAVYRLQEKSQSMFLGSALFQGQLRIDLIFLYSFCRVMDDLIDEAEDEQEARFWVTECRHLLDSTHRSEPHSDHFYTGKKGEEHERLRQSISYLPPSHLSNDSFDDLLKGFEIDLKFNPQREAFPIQSEYCLDQYAGFVAGTVGVLVFDLTLFHCGHYFIQDVPRLRRAAKDMGKAMQCQPRGDGGATSGRKRAIAGNRGELYGYWTTAEGAERHKPGASVEDEGAFGATAKSWLAGDVITELCHCFIQAEYVIYLVRHQNASADTLVLLSALVYRLE
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOH_SERP5
Sequence: MSWFTPEVIDILISIVKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWVPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPTWAVSDLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFIGLSLMGVVAQADSFNMQAIVESQAHMWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALIVTLFFGGWQGPFLPPFVWFALKTAFFMMMFILIRAALPRPRYDQVMSFGWKVCLPLTLLNLLATAAVILYNAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMA_CHLTR
Sequence: MARSSIEQLTSFLRSVNGRAKKALSQNFLVDGNILRKILTTAEVQPGDWVLEIGPGFGALSEVLLSQGANVIALEKDPMFEESLSQLPMDIEITDACKYPLTSLEDKGWKGKGRIVANLPYHITTPLLTKFFLECPYRWKTVTVMIQDEVARRITAKPGDKDYGSLTVFLSFFADVQYAFKVSPNCFYPKPSVHSAVVHMRVHEQFALADSEIEEFFTLTRAAFGQRRKLLANSLKNLYPKDKVFQVLEQLGFSEKTRPETIFLEEYLKIFHLLKDI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN182_MOUSE
Sequence: MASQPLEEPAESQASDELECKICYNRYNLKQRKPKVLECCHRVCAKCLYKIIDFGDSPQGVIVCPFCRFETCLPDDEVSSLPDDNNILVNLTCGGKGKKCLPENPTELLLTPKRLASLVSPSHTSSNCLVITIMEVQRESSPSLSSTPVVEFYRPASFDSVTTVSHNWTVWNCTSLLFQTSIRVLVWLLGLLYFSSLPLGIYLLVSKKVTLGVVFVSLVPSSLVILMVYGFCQCVCHEFLDCMALPS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.  Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF182, RING finger protein 182, RING-type E3 ubiquitin transferase RNF182.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm.
Protein: SIGK_MYCSK
Sequence: MTALTQPVRLPFVTTDLDVLLRQVAERDVDAFAALYDRTRSRVYGMVTRVLRDPGYSEETTQDIYLQVWRSAGSYDPKAGSPMAWLLTLAHRRAVDRVRSEEAASQRESRYGAASVDPPVDHVADSVILLDERRRVVDCMGSLSDLQREAIQLAYYEGLTYVQVSERLSANLATIKSRMRGGIRGLKNCLGMS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigK, ECF sigma factor SigK, Alternative RNA polymerase sigma factor SigK, RNA polymerase sigma-K factor, Sigma-K factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: TXH1_CYRSC
Sequence: MRASMFLALAGLVLLFVVCYASESEEKEFPRELLFKFFAVDDFKGEERACKGVFDACTPGKNECCPNRVCSDKHKWCKWKL
What is the function of this protein?
Lethal toxin with multiple biological activities.  Inhibits voltage-gated TTX-sensitive sodium channels in DRG neurons (IC(50)=55 nM) and also shows activity when directly tested on Nav1. 7/SCN9A (IC(50)=25. 1-630 nM) (PubMed:17451655, PubMed:21731778, PubMed:31234412).  Inhibits N-type calcium channels (Cav2. 2/CACNA1B (IC(50)=100 nM)) (PubMed:11024489, PubMed:17451655).  Also blocks neuromuscular transmission (PubMed:8212049, PubMed:9028007, PubMed:10736477).  In vivo, intrathecal injected toxin shows analgesic activity in the rat formalin-induced pain model, without induction of motor dysfunction in rats.
What are the official names of this protein?
Mu/omega-theraphotoxin-Hs1a, Mu/omega-TRTX-Hs1a, Huwentoxin-1, HwTx-1, Huwentoxin-I, HwTx-I.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 23 (HwTx-I) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: POLH_ARATH
Sequence: MPVARPEASDARVIAHVDMDCFYVQVEQRKQPELRGLPSAVVQYNEWQGGGLIAVSYEARKCGVKRSMRGDEAKAACPQIQLVQVPVARGKADLNLYRSAGSEVVSILAKSGKCERASIDEVYLDLTDAAESMLADAPPESLELIDEEVLKSHILGMNREDGDDFKESVRNWICREDADRRDKLLSCGIIIVAELRKQVLKETEFTCSAGIAHNKMLAKLASGMNKPAQQTVVPYAAVQELLSSLPIKKMKQLGGKLGTSLQTDLGVDTVGDLLQFSETKLQEHYGVNTGTWLWNIARGISGEEVQGRLLPKSHGSGKTFPGPRALKSLSTVQHWLNQLSEELSERLGSDLEQNKRIASTLTLHASAFRSKDSDSHKKFPSKSCPMRYGVTKIQEDAFNLFQAALREYMGSFGIKPQGNKLETWRITGLSVSASKIVDIPSGTSSIMRYFQSQPTVPSRSADGCVQGNVAMTASASEGCSEQRSTETQAAMPEVDTGVTYTLPNFENQDKDIDLVSEKDVVSCPSNEATDVSTQSESNKGTQTKKIGRKMNNSKEKNRGMPSIVDIFKNYNATPPSKQETQEDSTVSSASKRAKLSSSSHNSQVNQEVEESRETDWGYKTDEIDQSVFDELPVEIQRELRSFLRTNKQFNTGKSKGDGSTSSIAHYFPPLNR
What is the function of this protein?
Error-free DNA polymerase specifically involved in DNA repair.  Plays an important role in translesion synthesis (TLS), where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls.  Plays an important role in the repair of UV-induced pyrimidine dimers and confers resistance to ultraviolet light.  Depending on the context, it inserts the correct base, but may cause base transitions and transversions.  Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.  Targets POLI to replication foci.  Exhibits cyclobutane dimer nonmutagenic bypass activity in vitro.
What are the official names of this protein?
DNA polymerase eta, Radiation-sensitive protein 30, AtRAD30, Y-family DNA polymerase H, AtPOLH.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates at replication forks after DNA damage.
Protein: Y997_GEOSW
Sequence: MFPKRQGIIVWLHSLKHSKHLRKFGNIHYVSKRLKYAVLYCDMEQVDEMMKKLASLPFVKRVEPSYRPFLKLEFESKGEKEKNSSYPLGYSAE
What are the official names of this protein?
UPF0298 protein GWCH70_0997.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX3Y_PONAB
Sequence: MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGWSCSKDKDAYSSFGSRDSRGKSGYFSERGSGSRGRFDDRGRSDYDGIGNRDRPGFGRFERSGHSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDLLGATGRDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGSGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
What is the function of this protein?
Probable ATP-dependent RNA helicase.  May play a role in spermatogenesis (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX3Y, DEAD box protein 3, Y-chromosomal.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm in an XPO1- dependent manner.
Protein: MNMC_ALIF1
Sequence: MSQNHILPQNSITNAVLEWNESGTPVSNDFDDVYFSNDNGLEETRYVFLQQNHLPQRWQEYDQRRFVIGETGFGTGLNFLAVWQWFKEFRSQYPDAPLKELHFVSFEKFPVTKSDLIKAHQAWPELAQFAEQLQEHYPAAVPDCHRLVLEDGMITLDLWFGDIKDCMPQIWMDDKGLIDAWFLDGFAPSKNPEMWNQTLFNNMASLAKKGCTCATFTAAGFVRRGLIEAGFDMKKVKGFGHKREMIAGTLTERTTKANHEVWYARSTKENITDVAIIGGGVASAALATTLIRRGVKVSVYCKDEKSAQGASGNKQGAVYPLLNEKFNSLSRFFAPGFIFARQFIDQAAKHVEFDHDWCGVTQLKWDEKSANKLNKMLEGNFPNELVSSFDIDKTNQMVGLPINMESVHYSLGGWLCPKQLTRGLFEHLSNNPLFTLHCDSEIIALTQNEEQQWLLSTDSNAYQHQAVVVANGHRFTDFEQTKDIPATPVRGQVSHIPTTESLKNLKTVLCYDGYLTPENSKHQTHCIGASYDRRDLDLAFKESDQIENGERLRKCVPNEVWPNDVDTSDNQARVGIRCASRDHLPFIGNVVRFEEMQEEYKNIYKKRHWLREAKDIPVYEGLFCMLTLGSRGLSSAPLLAEALASQIMGDPIPLPNSVLEGLHPGRLWVRRLLKGKPLDI
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_ALIFM
Sequence: MSDIMSNFSWLYGKPVATGKLKQLPEHFIVKEILGFEFTGSGEHLMVKIRKTGENTKYVANELAKFCGVKSKNVSWAGLKDRHAVTEQWLSVQVANSDELSFAKFEATHPGVEILEVTRHNKKLRPGDLQGNQFQVIATEVTDIEDVLARLEKVKLTGVPNYFGSQRFGHEGNNVNEARRWGRDNVRTRDNSKRSFYLSAARSWIFNHIVSQRITEGYFSQPVDGDILLDRNDRIVNENVTSEESIQKIQNGELSITAALAGDNQLPTTGTALTLEQPHLDAEPDLMALIRGNRMRHERRAIELHPENLTWSAEGDTLTLNFSLTSGSFATVIVRELLQEIEVERTYSSND
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CHIA_SOLLC
Sequence: MKFNIVSPVALSCLFFLFLTGTLAQNAGSIVTRELFEQMLSFRNNDACPAKGFYTYDAFIAAANSFPGFGTAGDDTARKKEIAAFFGQTSHETNGGSAGTFTGGYCFVKQIEQSDRYYGRGPIQLTHQSNYERAGQGIGVGQELVNNPDLVATDPIISFKTAIWFWMTEQDNKPSCHNVIIGQWTPSPKDTAANRVPGYGVITNIINGQFECGMGPNTAAESRIGFYRRYCGMLNVPTGENLDCNNQKNFAQG
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Acidic 26 kDa endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MTF1_LACKL
Sequence: MSVHIPTLNSATKIKHYYGFKYLLNSSVHTQIYNKLQLQSTYKMDELKVLDLYPGPSQHSAIFRNIFNPKQYVLMDSRPDFVKFIQDNFAGTSMELYQRDPYEWSSYTDMIEKEKRFVPNRQSRDKIHNQFLVMANLTGMIGEGLFMQWLSCIGNKNWLQRFGRVKMLVWVPEATAHKVLARPGSLIRAKCSVVTEAFTDTKLVATSDSSTLQKFSSSLLEGHDPIIFSTRDTWLNSGKPISLLEVNPIDHDIDLDNWDYVTKHLLILKSTPLHTAIDSLGHGGKQYFSEKVEDKLLMDKCPKDLTNKEFVYLTSIFNNWPFKPDIYMDFIDVFQENE
What is the function of this protein?
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase.  Interacts with DNA in a non-specific manner (By similarity).
What are the official names of this protein?
Mitochondrial transcription factor 1, Mitochondrial transcription factor mtTFB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SUVH8_ARATH
Sequence: MVSTPPTLLMLFDDGDAGPSTGLVHREKSDAVNEEAHATSVPPHAPPQTLWLLDNFNIEDSYDRDAGPSTGPVHRERSDAVNEEAHATSIPPHAPPQTLWLLDNFNIEDSYDRDAGPSTSPIDREASHEVNEDAHATSAPPHVMVSPLQNRRPFDQFNNQPYDASAGPSTGPGKRGRGRPKGSKNGSRKPKKPKAYDNNSTDASAGPSSGLGKRRCGRPKGLKNRSRKPKKPKADDPNSKMVISCPDFDSRITEAERESGNQEIVDSILMRFDAVRRRLCQLNYRKDKILTASTNCMNLGVRTNMTRRIGPIPGVQVGDIFYYWCEMCLVGLHRNTAGGIDSLLAKESGVDGPAATSVVTSGKYDNETEDLETLIYSGHGGKPCDQVLQRGNRALEASVRRRNEVRVIRGELYNNEKVYIYDGLYLVSDCWQVTGKSGFKEYRFKLLRKPGQPPGYAIWKLVENLRNHELIDPRQGFILGDLSFGEEGLRVPLVNEVDEEDKTIPDDFDYIRSQCYSGMTNDVNVDSQSLVQSYIHQNCTCILKNCGQLPYHDNILVCRKPLIYECGGSCPTRMVETGLKLHLEVFKTSNCGWGLRSWDPIRAGTFICEFTGVSKTKEEVEEDDDYLFDTSRIYHSFRWNYEPELLCEDACEQVSEDANLPTQVLISAKEKGNVGRFMNHNCWPNVFWQPIEYDDNNGHIYVRIGLFAMKHIPPMTELTYDYGISCVEKTGEDEVIYKGKKICLCGSVKCRGSFG
What is the function of this protein?
Histone methyltransferase.  Methylates 'Lys-9' of histone H3.  H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH8, Histone H3-K9 methyltransferase 8, H3-K9-HMTase 8, Protein SET DOMAIN GROUP 21, Suppressor of variegation 3-9 homolog protein 8, Su(var)3-9 homolog protein 8.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: MYF6_TETNG
Sequence: MMDLFETNTYLFNDLRYLEEGDHGPLQHLDMPGVSPLYDGNHSPLSPGPDNVPSETGGESSGDEHVLAPPGLRAHCEGQCLMWACKVCKRKSAPTDRRKAATLRERRRLKKINEAFDALKRKSVANPNQRLPKVEILRSAISYIERLQELLQSLDEQERGQSGASDTRNDKEQNRPSGGDYCWKKASETWPTSADHSAIINQRDGACESSASSSLLCLSSIVSSISDDKTDLRQGVQED
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenic factor 6, Myf-6, Muscle-specific regulatory factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2550_GEOSW
Sequence: MTFMIRDVPKDARPRERLLSSGPESLADHELLAILLRTGTKEESVLQLAHRLLKHFEGLRLLKDATIEEITSIKGIGTTKAVQILAAIELGRRISRLSYNGRYVIRSPEDGAKYVMEDMRFLSQEHFVAIYLNTKNQVIHRKTIFIGSLNASIVHPREVFKEAIKRSAASIICVHNHPSGDPTPSREDIDVTKRLAECGRIIGIELLDHLIIGDQKFVSLKEKGYV
What are the official names of this protein?
UPF0758 protein GWCH70_2550.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: NQOR_YERPY
Sequence: MAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: CALM_SOLLC
Sequence: MAEQLTEEQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMISEVDADQNGTIDFPEFLNLMARKMKDTDSEEELKEAFKVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVRMMLAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: TUS_ECO27
Sequence: MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGTL_PLAF7
Sequence: MKVVSCNYRVKNVKDIETPTYTILTNNITPEYINLELLRKIDKKFIINCSLLEIYNNLDVFEKVKEYFSSNKTNEVSGHYLHEFCDFQDSYRYLNIRNVLVDDYNINVHKFISLKYDNSTAVFSIDDYIKCLKIFEPDIFCIPCEEIKINEQVGKKKKNRIINLMNEFLEKVQIIKNTNLSNSLCILSIPCTVDIDTVITETINKYDSIIDGILLSGLGYDESNETRTNAFKNILNILPNNKLKFIQLSNGNPIEILHAIYHGIDVIEPNFPYYLAKNGKAINMNLKMDNLQDGNEYNLQDKNNDNIYDINLLDFKNDVNFIIDLNNPKYVLDHSTITCNSPRKESKSYIHHLLKCHELTAHVILTYHNLYIYRSFFQEIQLHIKENNFLSYINWFIEKNELNKKEE
What are the official names of this protein?
Queuine tRNA-ribosyltransferase-like protein.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DEF_MOOTA
Sequence: MAIHKILTLGDPLLREKSQPVRKITSNVWKLLDNLADTMYDAPGVGLAAPQIGVLKRVIVVDVGEGLTELINPEVIAASGEEVGAEGCLSIPGAQGEVPRAAVVTVRGLDRHGRVREIRAEGLYARALQHEIDHLDGILFIDKVVRWLENQPGER
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SSRP_YERE8
Sequence: MTKKKAYKPGSATIAQNKRARHEYFIEEEFEAGLSLQGWEVKSLRAGKANISDSYVTFRNGEAFLFGATITPLNVASTHVVCEPMRTRKLLLNKRELDSLIGKVNRDGFTVVALSVYWKNAWVKVKIGVAKGKKDHDKRDDIKDREWKLDKARIMKHANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.