PharMolix/UniProtQA huggingface dataset:
Protein: URE1_ACIAD
Sequence: MKMSRRAYAEMFGPTVGDRVRLADTELFIEVEQDLTTYGEEVKFGGGKVIRDGMGQSQLLADEVADTVITNALIVDWWGIVKADVGLKNGRIWKIGKAGNPDIQPDITIPLGAATEVIAGEGQILTAGGIDTHIHWICPQQVETALMSGVTTMVGGGTGPAAGTSATTVTPGPWHIGTMLQAIDDLPMNIGLLGKGNLSLPDPIREQIKAGVVGLKLHEDWGSTPAAIDNCLSVADEFDVQVAIHTDTLNESGFLEETLAAFKNRTIHTYHTEGAGGGHAPDILKAIGQANVLPSSTNPTRPYTINTIDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILQDLGAIAMMSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALQGDETSHDNSRVKRYIAKYTINPAITHGLSHEIGSVEEGKLADLVLWKPAFFGVKPSMIIKGGMIAAAPMGDINASIPTPQPVHYRPMFGAYPRGVHNTCITFLSQAAIDDGVAEKLKLKKLISPCKNTRQITKADMKHNTYCPVMDVHPETYEVRADGELLTCEPADVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_XANP2
Sequence: MTAFRTLDDADLADKRVLVRVDLNVPMESGRVTDETRLKAILPTIRTITDKGGKAVLLAHFGRPKGRDESQSLAPVAKALEGQLGRKVAFASDCVGEEASSAISRLAAGEVIVLENTRFHAGEEKNAPDFVEALASLGDIYVNDAFSAAHRAHASTEGLARKLPAYAGRSMESELAALTKALEAPVRPVLAVVGGSKVSSKLELLGNLVKKVDILVIAGGMANTFLAALGKKVGKSLCEHDLADTAREILEKAKAAGCEIVLPVDAVVAKEFKANAANRVVSVDEVGDDEMILDAGPETVAVVAQKLDGAKTVVWNGPFGAFEMTPFDAATVAVARDVGKRTRAGTLLSVAGGGDTVAALNHAGVAGDFSYVSTAGGAFLEWLEGKALPGVEALRR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EREL1_ARATH
Sequence: MMQRRSPPKHRHDGTSPLPLGMDWSPPPRKWNGRDTVWPHDPRTGWSYCVTIPSWIVLPKSRNSDPVVFYRVQVSVQSPEGITTMRGVLRRFNDFLKLLTDLKRTFPRKGFPSAPPKGLLRMKSRAVLEERRCSLEEWITKLLSDIELARSVVVASFLELEAAARSACQDVDQNASDSNNDRSSTSSSPMVHPSLSLFHAGGSTLTSDYGSDTAYETSEVGSPSVGQDDISEIGTEDLTLDEDLTLTNPIEKLVNFSMSNIDEGLSMSETILEQLEDFPKHKVRSRYVNNILGKDVYNGNASKGVFLANNGSRLLSEPEPSTHSVMHDRNDSAERFALHTGQTSTSGLLISSRDSHLDLRQGPGVSLGTGLVCNPERQGSAQIVLPLELRNKLNRILLATNERLVNAKTDMEDLIARLNQEIAVKDYLNKKVNDLEGELETTKQRSKENLEQAIMSERERFNQMQWDMEELRQKSYEMEMKLKSREDGSSHAEPTVQSTISEKHVLSKELDARKQQLEDLSRRYEELEAKSKADMKVLVKEVKSLRRSHVELEKELTHSLTDKTNAEKLLQEERKLLENTVAARKKLLSDCRILHDRLKEYNLNLSMDGNGNFVDDSTTISDVLRLLSISDDQIEEAQLLSGFDENAAAEDIDKTLSMDTETRIMEDELRKILANIFVENAKLRKQVNSAMLRALQKDVKTTEDVNEENSDEKDEASRETLKR
What is the function of this protein?
Acts as an effector of RABF2A and RABF2B (By similarity).  Involved in vacuolar transport of storage proteins.  Regulates membrane trafficking to protein storage vacuoles (PSVs) (PubMed:27288222).  Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P) (By similarity).
What are the official names of this protein?
PX domain-containing protein EREL1, Protein EREX-like 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein. Note=The endosomal localization depends on the active state of RABF2B.
Protein: PB2_I68A3
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKXAQDVIMEVVFPNEVGARILTSESQLTITKEKREELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGVRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGKDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEVSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQQGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: BIOB_ACAM1
Sequence: MSEETFPQASALTLLSDPNIDLLSLVAAAGEVRMTYFGRQVMLHRINDIQNGLCPEDCGYCAQSKISDAPIKKYPLKSEEDIIQEAYEAKAKGVYRYCMVSSGRGPTAERTEHLAHIIRRIKNEVGIQTCLSAGLMDHEQAAVLKEAGLDRLNHNLNTSESHTPDIVTTHTFQDRINTLKAARSAGLDLCSGMIAGMGETDQDIVDIAYQLHEYQVPSIPINFLIPISGNPIYDCNQLTPQRCLRILCLFRFVNPKAEIRIGGGREGHLRSLQALALYPANSLFVEGYLATRGHSVDQVYQLIHDAGFEVAGETSLTGDLSATSQFQLDDNPNILNPQTTISFSNS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NADK_DESRM
Sequence: MNTIGLVVNSSKGDVAKPVREVISWLAEQRIKVLYNEESAVLLGCPEEGISTRELGAQCDCIMVWGGDGTLLNCARQTASSGTPIFGVNLGRLGFLTEIDIPDLRERLQALIAGHFYIEERMMLEATVIRGGQVVDQAVCLNDAVVSKGASFRMVQLRILVNNEFVGSFAADGVIVASPTGSTAYSLAAGGPIISPDMEAMLITPICPHSLSNRPIVISPQSKVEVQVLPYVDKVGLNLDGQYGLPLREGDRILINRATVKARFLKIQKTGFYDVLREKLKEWQNGLD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_CALFG
Sequence: MVTIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLTIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKAAVATDTILNQKGQNVVCVYVAIGQKASSVAQVVTTFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTSIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSPLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQAAPLTVEEQIVTIYTGANGYLDPLEIGQVKKFLVQLRTYLKTNKPQLQEIISSTKTFTEEVEALLKEAIPEQIELFLLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HUTI_STAS1
Sequence: MNDLIIQNIKELILPKSTERPLKGKELGELNITENGTVVVKNGKIVYAGEHSDAYEATETIDATDKVVSPALVEAHTHLVHGGSREHEMSLKRQGVSYLEILEQGGGILSTVEATRKATEEALFKKAEKNLLTMMEHGVLAVESKSGYGLDKENELKQLRVSNRLAEKYNLDMKHTFLGPHAVPKDAESNQDFLQEMIDLLPEVKAYADFADIFCETGVFTVEESKKYMEAAKALGFDVKIHADEIDPLGGLELAIDENAISADHLVASSTEGKEKLKNSDTVAVLLPGTTFYLGKESYADARGMLDNDGAIAIATDFNPGSCVTNNLQLVMSIAALKLKLSPNEIWNAVTVNAAKAIDIDAGTINQGDKANIVIWDAPNHEYIPYHYGINHAEKVIKDGKVLIDNRIKLEQ
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_PECAS
Sequence: MSTIEERVKKIIVEQLGVKQEEVVNNASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFIQANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_BACMK
Sequence: MTAIRYEFIKTCKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEELKAMDSGIILSNTYHLWLRPGHEIVREAGGLHKFMNWDRAILTDSGGFQVFSLSDFRRIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLKAHERPQDQGLFGIVQGGEFEELRRQSAKDLVSMDFPGYAIGGLSVGEPKDIMNRVLEFTTPLLPDDKPRYLMGVGSPDSLIDGAIRGVDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFARDFGPLDPNCDCYTCKNYSRAYIRHLMKCDETFGIRLTSYHNLHFLLNLMEQVRQAIREDRLGDFREEFFEQYGFNKPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ASTB_ECOBW
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: MSMP_MOUSE
Sequence: MALRMLWAGQAKGILGGWRTICLVVSLFLQHPGVSSKCYFQAQAPCHYEGKYFTLGESWLRKDCFHCTCLHPVGVGCCDTAQHPIDFPAECEVLQEAGTCQFSLVQKADPRLPCKGGGPDLEWGSANTPAPGASAPHSS
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and lymphocytes but not neutrophils (By similarity).
What are the official names of this protein?
Prostate-associated microseminoprotein, PC3-secreted microprotein homolog.
What is the protein family that this protein belongs to?
Belongs to the beta-microseminoprotein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTB_ZYMMO
Sequence: MIVSEVNFDGLIGPTHNYAGLSRGNVASALHAGQPSYPRQAALQGLEKMKHLMDMGLTQGVFLPPLRPVTHLLHHLGYKGDDKTILKQAAKDDRLLFNNLCSASSMWAANAATVISEFDSHDGRVHFITANLATMLHRHLEAQTTYAQLNQIFSNSCFFAMHHPLPCGQHFSDEGAANHMRITSAHGRTGINIFVYGEKNDIYPARQKLRASQAVARLGEVKPDLAWFIPQKKEAIAKGAFHNDVVAVANEYVLLAHAEAFEDQGEWIKRIAEKIDGFIPIIIDNITLEQAVKSYLFNSQIVTLKDRTMALILPQEVKSDPAVWETVNRIISGNNPIKKAVVVDVRESMANGGGPACLRLRVPLSKAALEAVDQRFILTPKRWEKLYQLVENFWPEKITPDDLVLPELWKTAVRAHWALTSWLG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: RSXD_SALSV
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLIAALPGIAAQTWFFGWGTLFQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDMLDTLRMIFTGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGVGWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPIA_USTMA
Sequence: MASSNATNSTSAASAANTNSSAFKSAELAALSGVEAAKRAAAYAAVDNHVKPQHEIIGIGSGSTVPYVVERIAQQGPAVNAKRWFVPTGFQSRELIINAGLRLGDVDSFPSIDVTIDGADEVDNALNCIKGGGACHLREKVLAEAANEFVVVADYRKNGSQLGTKWLQGVPIEVAPFAYAKVLQNLKKMGSDKAVLRMGKAKAGPVVTDNGNFCIDAPFPEAQMKDPSDLLKRIKLLTGVLEVGLFCNICKSAYFGNDDGTITIKTAAGDVQEGVHFDVSKAPATA
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL41_CANAL
Sequence: MRDKWRKKRVRRLKRKRRKVRARSK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
Protein: CH10_HELPH
Sequence: MKFQPLGERVLVERLEEENKTSSGIIIPDNAKEKPLMGVVKAVSHKISEGCKCVKEGDVIAFGKYKGAEIVLDGTEYMVLELEDILGIVGSGSCCHTGNHDHKHAKEHEACCHDHKKH
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_BACCN
Sequence: MLHRYLPMTEEDKKEMLETIGVQTIDELFSDIPESVRFKGDLKIKQAKSEPELLKELSGLARKNANLKEYASFLGAGVYDHYAPVIVDHVLSRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSKAVHPESRAVLETYAKGQHLEVVEIDHKDGVTNLDGLQSEMDDTVACVIVQYPNFFGQIEKLADIEKIVHEQKALFIVSSNPLSLGVLTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDTEGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKRGVKEMARQNISKAQYAKRQFEEKGFKVVFTGPFFNEFVVDCKRPVKEINDTLLQKGIIGGYDLGRDDEKLVNHMLVAVTELRTKAEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: PGLR1_COLLN
Sequence: MVSYLFVLGALASVAIASPVPELKARASCTFTDAASAIKGKASCTTIVLNNIAVPAGTTLDMTGLKSGTHVSFSGKTTFGYKEWEGPLISFSGSNVVIDGASGHSIDCQGSRWWDSKGGNGGKTKPKFFYAHSLKDSTIRGLHTLNTPVQAFSINGAANLGVYDVSVDNSAGDSAGGHNTDAFDVGSSTGVYISGADVKNQDDCLAVNSGTNITFTGGTCSGGHGLSIGSVGGRKDNVVKSVSITNSKIINSDNGVRIKTVAGATGPVSDITYSGITLSNIAKYGIVIEQDYENGSPTGKPTSGVPISGLTLSKISGSVSSSATPVYILCASCTNWKWSGVSVTGGKKSSKCTGIPSGSGAAC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase 1, Clpg1, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ROGFE_ARATH
Sequence: MMLMRRRLACCSREREISIDFDEHEQDKMITYYGLETCIINNQSYEEESGTSRGDGCLTDSLDDDAFSSCSSSKDASSSFSSKWLPMKNDEHSCDGLNLSGRSQHFDAKEKKKQGYGSSQHFDAKEKPGYVYCHLDVEAMKEKFSKLLLGEDVTGGCKGVQVALALSNAVTHLATSIFGELWKLEPLCEEKKQKWRREMDWLLSPTNYMIELVPSKQNDANGRSLEIMTPKARADIHMNLPALQKLDSMLIETLDSMVNTEFWYSEIGSRAEGKNKSTSESKRWWLPSPQVPKPGLSNSGRKKLLDKGKVVYQVFKATKAINENILLEMPVPIVIKEAIPKSGKNSLGDELYKMLAVESATVDEIFISLNLGTEHAALETVNKLESAMFAWKERITEQGSNGKSPVRASWSFAKDPLSEIGRNESLLNRAEALRTQIKSKHPNLPHSFLDATKIQYDKDIGHAVLEAYSRTLANLAFRILSRMGEILKEDSLSNPNSPAPPSCFPSSRDPYRTPERPLLSSRVRHSLTDDMNKADGTETGLDFLFADAKASNSVNTTPSRSSRLWCLSKVPSDTSP
What is the function of this protein?
Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.
What are the official names of this protein?
Rop guanine nucleotide exchange factor 14, AtRopGEF14, Rho of plants guanine nucleotide exchange factor 14.
What are the subcellular locations of this protein?
Cell membrane. Note=Localizes to the apical region of the pollen tube plasma membrane.
Protein: CH603_NITWN
Sequence: MAAKDVKFSGDARQRMLRGVDILADAVKVTLGPKGRNVVIERSFGAPRITKDGVTVAKEIELEDRFENMGAQMVREVASKTNDLAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDIAVAAVVKDIGKRAKAVASSAEVAQVGTISSNGDASIGKMIAQAMQKVGNDGVITVEENKSLETDVDIVEGMKFDRGYLSPYFVTNAEKMAAELDDAYILLHEKKLTGLQALLPVLEAVVKSGKPLLIVAEDVEGEALAALVVNRLRGGLKVAAVKAPGFGDRRKAMLEDIAILTSGQLISDELGMKLENVTLNMLGRAKKVLIDKENTTIVNGAGKKKDIEARVGQIRARIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEIEVKEKKDRVEDALNATRAAVEEGIVPGGGTALLRARKAVGRINNDNSDVQAGINIVLKALEAPIRQIAENAGVEGSIVVGKILENKTETFGFDAQKEEYVDMVAKGIIDPAKVVRTALQDASSIAGLLVTTEAMVAELPKDEPPAMPAGGGGMGGMGGMGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL85_SCHPO
Sequence: MPASKYAGWSRDQLISRILELDGKLQKNTNSLPNKEIEGKNEVIKNKNKLDNGNEIEPQHLSQELVLQHALQDASSLPKLKPVRPFQLEKTVFVAFKFAYCGWNYNGLAYQLEPTPLPTVEGKVFEALLRAHLITDPSSCSFSRCGRTDKGVSAMGQVISLNVRHSERRPIIYCDVLNRLLPADIRITGYAFPPEGFDARFSCKQRHYKYLFTKDYPGGSLDIDRMNEAAALYLGEHDFRNFCKIDASKQITNYHRRILSSKVICIDPSTGLYAFDLQGTAFLWHQVRCMMAILFLIGQKLEPASLINDLLDIKKVPTKPIYDMASEYPLILYDCDFDNIEWTLPTDSPTTAPRIAKHTYETIYHQWHSLRIREQIASFMLDIADHNVKRYGKSEESSSTMNVGEGLLKRTKKYIPILSRQRQESVEVVNERYKRKKGLKDSDVKSENIK
What are the official names of this protein?
Putative tRNA pseudouridine synthase C25B8.05.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VM2P3_PROMU
Sequence: MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVSALPKGAVQPKYEDTMQYELKENGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIHNDADSTASISACDGLKGYFKLQGQTYLIEPLKLPDSEAHAVFKYENIEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRYVKLAIVVDYRMYIKYNRDSNKITVRVHEMVNHVNEMYKPLNVAITLSLLRIWSTRDLITVQSDSKVTLGSFGDWRKTVLLKQQSHDCAHLLTDITFTKNVIGVAYKKGMCDPKLSVGLVQDYSSNVFVVAAIMTHELGHNLGMEHDEDENGKKCKCDTCIMSPAISDPPAQLFSDCSKNDYHTFLTNSKPQCILNAPLRTDTVSTPVSGNEPL
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SHH_CYNPY
Sequence: MDEMILLRRVLLAGFICALLVPSGLSCGPGRGIGTRKRFKKLTPLAYKQFTPNVPEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDRSKYGMLARLAAEAGFDWVYFESKAHIHCSVKAENSVAAKSGGCFPGSATVALEQGVRIPVKDLRPGDRVLAADGLGKLVYSDFLLFMDKEETVRKVFYVIETSRERVRLTAAHLLFVGQAHPGNDSGGDFRSVFGSAGFRSMFASSVRAGHRVLTVDREGRGLREATVERVYLEEATGAYAPVTAHGTVVIDRVLASCYAVIEEHSWAHWAFAPLRVGLGILSFFSPQDYSSHSPPAPSQSEGVHWYSEILYRIGTWVLQEDTIHPLGMAAKSS
What is the function of this protein?
The dually lipidated sonic hedgehog protein N-product (ShhNp) is a morphogen which is essential for a variety of patterning events during development.  Induces ventral cell fate in the neural tube and somites (By similarity).  Involved in the patterning of the anterior-posterior axis of the developing limb bud (By similarity).  Essential for axon guidance (By similarity).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).  In the absence of SHH, PTCH1 represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Sonic hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane. SUBCELLULAR LOCATION: [Sonic hedgehog protein N-product]: Cell membrane; Lipid-anchor. Note=The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (By similarity). Further solubilization and release from the cell surface seem to be achieved through different mechanisms, including the interaction with DISP1 and SCUBE2, movement by lipoprotein particles, transport by cellular extensions called cytonemes or by the proteolytic removal of both terminal lipidated peptides.