PharMolix/UniProtQA huggingface dataset:
Protein: RT04_ACACA
Sequence: MYKFYKHKLYKKYQDELWGHIISKKSFSYNKKSILLNYRDIILRNRLRIKTKFKYFRRGFLKNLNYTLLLFKFFRKNIRVFSFKRRQSLSVPLSLSSKRFKTKRKVFFKTSKIASLLKFNIFYANTVAFNKVFIKHNYCLSSCSNIYTQTKLLYFPIISVNRGLVFYKSKNFLRVNNLQFVIKKKLNLRKQKIFFYSVHIAAPKKKTKKWSLFALKNIYYKKVSLFFGFRKVVDFFKVYNLAGALAKGNSFAVFLMLEGRLENFLMRLNLFPSIYFIKKFIEYGNVFVNNKIINYTSYHLNFNEIVSFNKKYYKKLYFFIKSKLRQRKVIINAPSFVEVDYKLLVAMLIRNPDELALTKPLSFNLYTKFLSVNR
What are the official names of this protein?
Ribosomal protein S4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CEMA_MAIZE
Sequence: MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSETFLTDIQEKRILEGFIELEELFLLDEMIKEKPKTHVQKLPIGIHKEIIQLAKIDNEDHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSIKAFFILLVTDFFVGFHSTRGWELLIRWVYNNLGWAPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: MDTK_ECOLI
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that probably functions as a Na(+)/drug antiporter.  Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP) (PubMed:9661020, PubMed:11566977).  Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium (PubMed:11566977).  Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth (PubMed:20067529).  Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide (PubMed:20067529).
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: S6A19_MOUSE
Sequence: MVRLVLPNPGLEERIPSLDELEVIEKEEAGSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAYAQLKFQTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSFAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWDPNYEEFPKSQKIPYPNWVYAVVVTVAGVPCLSIPCFAIYKFIRNCCQKSDDHHGLVNTLSTASVNGDLKN
What is the function of this protein?
Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells (PubMed:18424768, PubMed:17167413, PubMed:26240152, PubMed:19185582, PubMed:15044460).  This uptake is sodium-dependent and chloride-independent (PubMed:18424768, PubMed:19185582, PubMed:15044460, PubMed:21636576, PubMed:26240152).  Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity (PubMed:18424768, PubMed:17167413, PubMed:19185582, PubMed:22677001).
What are the official names of this protein?
Sodium-dependent neutral amino acid transporter B(0)AT1, Solute carrier family 6 member 19, System B(0) neutral amino acid transporter AT1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A19 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes in small intestine brush border membranes (at protein level).
Protein: DHNPA_PYRFU
Sequence: MKARIIYRASFDAAHAVKIEEWEELHGHTFSLEVVVEGEIKKGYVMDFLKLKKVVDGVVKELDHRNLNKIMDNPTTENIALWISERIRKNLPGDVKLKRLSLWEGNEFGVELEW
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin monophosphate (H2NMP) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).  Cannot use 7,8-dihydroneopterin (H2Neo) or 7,8-dihydroneopterin triphosphate (H2NTP) as substrate.
What are the official names of this protein?
Dihydroneopterin monophosphate aldolase, H2NMP aldolase, 7,8-dihydroneopterin monophosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the PTPS family.
Protein: BSSP4_HUMAN
Sequence: MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS
What is the function of this protein?
Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA.
What are the official names of this protein?
Brain-specific serine protease 4, BSSP-4, Serine protease 22, Serine protease 26, Tryptase epsilon.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: TOM34_PONAB
Sequence: MAPKFPDCVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDSVTSALEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKAKVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH
What is the function of this protein?
Plays a role in the import of cytosolically synthesized preproteins into mitochondria.  Binds the mature portion of precursor proteins.  Interacts with cellular components, and possesses weak ATPase activity.  May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM34, Translocase of outer membrane 34 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Tom34 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEG4_PIG
Sequence: MAFVPAPGYQPTYNPTLPYYKPIPGGLRVGMSVYIQGVANEHMKRFFVNFVVGQGPGADVAFHFNPRFDGWDKVVFNSQQDGKWGNEEKKRSMPFRKAPAFELVIMVLPEHYKVVVNGDPFYEFGHRIPVQLVTHLQVDGDLTLQSINFIGGQPAPSPGPMPNPGYPGPGKHNQQPCNLPCMEGAPTFNPPVPYKTRLQGGLVARRTIVIKGYVPPSGKSLVINFKVGSSGDVALHINPRLTEGIVVRNSYLNGKWGAEERKSSFNPFAPGQYFDLSIRCGLDRFKVYANGQHLFDFSHRLSNFQGVDTLEIQGDVTLSYVQI
What is the function of this protein?
Galectin that binds lactose and a related range of sugars.  May be involved in the assembly of adherens junctions.
What are the official names of this protein?
Galectin-4, Gal-4, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4.
Protein: AROC1_BACAH
Sequence: MRYITAGESHGPQLTTIIEGVPAGLPLVADDINEELARRQKGYGRGRRMQIETDQVQIVSGVRHGETLGSPIALVVENRDFAHWTKIMGAEPLTEQEEKEMKRKVTKPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVAAGAVAKKVLAELGITVAGHVIEIGGVEAKETTYRSIEELKSITEASPVRCLDEEAGNQMIKAIDDAKSNGDSIGGIVEVIVEGMPIGVGSYVHYDRKLDAKLAAAIMSINAFKGVEIGIGFEAAHRPGSEVHDEILWNEEHGYTRRTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLQSVDIDTKEPFTASIERSDSCAVPAASVVAEAVVAWELATALIEQFGLDRMDLIRENIEKHNEYARGF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 1, CS 1, 5-enolpyruvylshikimate-3-phosphate phospholyase 1.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HUTU_PHOPR
Sequence: MTQSTIPNPRLDESRTIIAPTGTQLNAKSWLTEAPLRMLMNNLHPDVAEHPHALVVYGGIGRAARNWECYDKIVEVLKRLEDDETLIVQSGKPVGVFKTHTNAPRVLIANSNLVPHWANWEHFNELDKEGLMMYGQMTAGSWIYIGSQGIVQGTYETFVAMARQHFNGDAKGRWVLTGGLGGMGGAQPLAATMAGFSMLAVECDESRIDYRLRTGYVDSKATTLDEALAIIEESKQTGKPVSVGLLGNAADVYADIVKRGIVPDVTTDQTSAHDPLNGYLPQGWSMEHAAAMRLEDEAIVVKAAKQSMAVQVQAMLALQEAGSATVDYGNNIRQMALEEGVENAFDFPGFVPAYIRPLFCEGIGPFRWVALSGDPEDIYKTDQKVKELIPDNPHLHNWLDMARERIQFQGLPARICWVGLKDRARLGKAFNEMVKNGELKAPIVIGRDHLDSGSVASPNRETEGMMDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDDAAERVGRVLRNDPATGVMRHADAGYDIAINCAEEQGLDLPMVNTKNTHSK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_BURPS
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRSHGRPSMFFPNVTQTNTASNATNGNGASGASAAAAANALPAAATGAAPATTAPAAQAQLVRFSTDVYNGEIDTRGGTLAKLTLTKAGDGKQPDLSVTLFDHTANHTYLARTGLLGGDFPNHNDVYAQVAGPTSLAADQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIENVGAAPVTPSVYMELVRDNSSVETPMFSHTFLGPAVYTDQKHFQKITFGDIDKNKADYVTSADNGWIAMVQHYFASAWIPQSGAKRDIYVEKIDPTLYRVGVKQPVAAIAPGQSADVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGFVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWVLWIHDLSQRDPYFILPVLMAVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRTLGGAAAKKKAS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_PODAS
Sequence: MAPRSYSKTAKVPRRPFEAARLDSELKLVGEYGLRNKREVWRVLLTLSKIRRAARELLTLDEKDPKRLFEGNALIRRLVRVGVLDESRMKLDYVLALKAEDFLERRLQTLVYKLGLAKSIHHARVLIRQRHIRVGKQIVNVPSFVVRLDSQKHIDFALTSPFGGGRPGRVRRKKAKAAEGGDGDAEEDEE
What are the official names of this protein?
40S ribosomal protein S9, S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YBEY_LEUCK
Sequence: MDLAIIDQTHDGVSRYHHDLVESVLNFAGEALKLPVNTEMSVTFVNNDEIQRYNRDYRGVDKPTDVISFAIEEGEDDFNIISDDAWTEDIAKNIGDIIVSVDIIGAQAEYLGHSYERELGFLVVHGFLHLNGYDHMLGDAEEKEMFDLQREILDNYGLKR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR5G3_HUMAN
Sequence: MEDKNQTVVTEFLLLGLTDHPYQKIVLFFMFLFVYLITLGGNLGMITLIWIDPRLHTPMYFFLRHLSFVDICSSSSVVPKMLCNIFAEKKDITFLGCAAQMWFFGLFEAAECFLLAAMAYDRYVAICKPLLYTLIMSQQVCMQLVVGPYAMALISTMTHTIFTFCLPFCGSNIINHFFCDIFPLLSLACADTWVNKFVLFVLAGAIGVLSGLIIMVSYICILMTILKIQTADGKQKAFFTCFSHLAAVSILYGTLFLIYVRPSSSSSLGIYKVISLFYTVVIPMVNPLIYSLRNKEVKDAFRRKIERKKFIIGR
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5G3, Olfactory receptor 5G6, Olfactory receptor OR11-213.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_CAMHC
Sequence: MSEAEYLKAVEMLNIWAKAYYTQDNPLATDIEYDVLYKKVETFENEFPDLKVSYSPTNRVGDAVSEGFEKINHKAKMWSMEDIFDDNELLAWLERGEKAGLEFFVEPKFDGASLNLTYENGVLISAGTRGNGETGENVTQNVKVINSIPLQIDYKEKIEIRGEVVIAKSDFDALNDERANSGENLFANPRNAAAGSLRQLDSAVVKSRHLKFFPWDVGENSLNFKKHSEIMEFVRNLGFLKDDFVRVCASLTDLRKAYVDLHEMRERKDILMDGMVIRINELTKCENMGYTIKFPRFMVAYKFPPVEKATKLIDINLQVGRTGVITPVGVLEPVNIDGATVRNATLHNFDEIARLGLMKGDIVSIIRSGDVIPKITGVFGARRNGSETPIKRPEFCPVCGSRLLVEDIFIRCQNLTCKARIVNSLIYFCSKKCMNIDGLGEAIINTLFEKGKIINISDIYTLKADDLEGLEGFKDKKISNLLASIENSRISPLYRFITALGIEHIGEVAARKIAEIFGENWLNASFDEILKIDGFGEAMAKSFVGFCEINREKIENLLSFLHLSAQKTEISQNVFTKKTVVITGTLSISRDEMKEKLIKMGANVTNSVSKKTDFVLFGKDAGSKLEKAKMLGVKAISEDEFKEML
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: EFG1P_EMENI
Sequence: MPKDFKPPRTPRKTPYPDRPHKSKSKSQPDREEKQHPSVNELKRRIRDVKRLLAKPDLSADKRVIQERALAGYEKELADEERRRERSRMIKKYHFVRFLDRKTATKEVKRLTRKRDELAKNSDIDEATKQKKLEQLNVRLHTANVNLNYTIYYPLTEKYISIYAEKKKKNEGQNEDEDVQMEGGPTQEEEIVTAATTAQKKAMLQTVEKCMQDGTLDLLREGKLNLNADSVTEGGTKTETKSKPKSKPSSKDTGVKTVGGKENAKPRTKTSDSKRGKSAKHTAPAPAESDSESDGGFFEI
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein efg1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HPNC_ZYMMO
Sequence: MEGACASTYRSVSIKTKNKLNAAALVSGKGHQDENFPVASFLINPEYRPIIMAFYQFARQADDVADNVIASKKDRLAILEDMRSSLTGESQSEPNAVVLRQTLITHGLDHTIVHGLDLLEAFRRDVSVNRYENWDALMDYCRYSASPVGRFVLDVHKESRNLWPMNDALCTALQVINHLQDCGKDYRMMNRIYIPSDIMEAVGATAGDLGRFHASLPLRQAIETAALKTKSLLKRSSGFSAAIHDKRLGVEVAVIQRLAESLTECLTKHDPLSERVHHNKAETLGLAFVAAAGRLFS
What is the function of this protein?
Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP).  Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ).
What are the official names of this protein?
Hydroxysqualene synthase, HSQ synthase, HSQase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. HpnC subfamily.
Protein: MVP_RRSVT
Sequence: MQLFIVKLDSRSSASNEILVLDINELRKYVSKHQLSFRGAQVHETNSEHSVRNWEDDNITMFFHTSNVFPSEKSVRHALFSRNSVHVCGPLNIGAFRDSLRVLQSPQFPIHTYGDDITVFDKLREFVVVPNSLAVVDMDTSAWERYTYSLFTDEPGTITLADETPPTISPTGRDSVSPVARFSPSISISSIAIGEVGSASKRRQRLVKQAKSSDKTPIPEIRLNKKDTVFAETGTEQASPKTEIVAATVHKIPVNHAEADKRVVVLKGRTKDKAQEVREVTSLARDTTGVEHELMQSVGDDSVQVSGELSGFGDESFEVSKTDVVGVENKQLALDRVPALEPCGEVSEDEELVSEGMYAVPLDLDIYAEKCPSPTPPNSPKKREKADHEPIDISSAMMKLRLIAAAFQKEMMAYDKIDCLSSDDPAYLLAQFCLRNLNGVFVPEYVEEHSSDEENADDPNQGWNGTPVHGSREIFEKLSESRLASMEMISNVKPIRWNSKKTTYAVTIERGNPNLIVTQSLTRGQSSQFRKVIRAFGCSTDYCLERLASRDYDAILMLMSSLSGACHATKSYCYLQIVAYGSFAAPECKELD
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Displays sequence non-specific nucleic acid binding activity.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Movement and RNA silencing protein VP6.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: RL21_DICT6
Sequence: MFVVVETGGKQYKLSVGSTVRVEKLQANVGDEVVLDKVLLVGKDDEVLIGQPYVEGAKVIAEVVKQDKYPKVIVFKFKRKKHYRRKYGHRQPYTQLSVKEIVLPQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FTSK_CHLTR
Sequence: MGKERKKASVSLSPQTVFAVKTCVYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSFLLYNFGVAAFLIPLNFGWLSFLNMKRTPAPLAFRKAAAFGAIPVCCAVLLSMISPAQNLPQFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLLIGAVGTGLIFLAILLCAIFYLIPKSFVLKKKALLDDLLKFLKNKFYACWNACKKLLKNLVNNKSYVPKPSLRVPSSPSVAKKEMLKLPTPVISLPLENKDLHDDSSVNRTIFLTPPHPTKRTLSPQKRTDLPNLLPKDSALAPAQTSYKPLPTPSPFVLAGDAPDLPQYHLLSKRNVHRPESLLEELKKKAAILQQTLASFGIEAAIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQASSIRIIAPIPGKAAVGIEIPNPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSVCINTIVMSLIMTSPPTDIKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVREMELRYEILRFLGLRNIQSFNSRTRNVDIEASYDKEISEKMPFIVGIIDELSDLLLSSSHDIETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFPSRIAFKVANKVNSQIIIDEPGAENLMGNGDMLVVSPGSFAPVRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFNTYDDPGSMDPEDLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGAKPRQILVQLSNQDD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: MEGL_FUSNN
Sequence: MEMKKSGLGTTAIHAGTLKNLYGTLAMPIYQTSTFIFDSAEQGGRRFALEEAGYIYTRLGNPTTTVLENKIAALEEGEAGIAMSSGMGAISSTLWTVLKAGDHVVTDKTLYGCTFALMNHGLTRFGVEVTFVDTSNLEEVKNAMKKNTRVVYLETPANPNLKIVDLEALSKIAHTNPNTLVIVDNTFATPYMQKPLKLGVDIVVHSATKYLNGHGDVIAGLVVTRQELADQIRFVGLKDMTGAVLGPQEAYYIIRGLKTFEIRMERHCKNARTIVDFLNKHPKVEKVYYPGLETHPGYEIAKKQMKDFGAMISFELKGGFEAGKTLLNNLKLCSLAVSLGDTETLIQHPASMTHSPYTKEEREVAGITDGLVRLSVGLENVEDIIADLEQGLEKI
What is the function of this protein?
Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia, and that of L-homocysteine (By similarity).  Can also use L-cysteine as substrate, catalyzing its alpha,beta-elimination; this activity seems to only minimally contribute to the production of hydrogen sulfide (H2S) by F. nucleatum in the oral cavity, which is toxic for a large variety of cells in periodontal regions (PubMed:21798982).
What are the official names of this protein?
L-methionine gamma-lyase, MGL, Homocysteine desulfhydrase, L-cysteine desulfidase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.
Protein: PCKG_FRACC
Sequence: MTTAAQVSGLDVAPTRHARLVAWVREIAELTQPDRVEWCDGSEAEFDRLTSLLIEQGTLVRLNDEKRPNSFYAASDPGDVARVEDRTYICSEQAEDAGPTNNWLDPAEMRATLRGLFAGCMRGRTMYVVPFCMGPLGSRISALGVEITDSPYVVISMRTMTRMGTPALEQLGTDGFFVPAVHSLGAPLEPGQADVPWPCNTTKYITHFPETREIWSYGSGYGGNALLGKKCYALRIASVMARDEGWLAEHMLILKLTSPAGKVHYIAAAFPSACGKTNLAMLIPTLPGWQAETVGDDIAWMRFGEDGRLYAVNPEAGFFGVAPGTGEQTNPNAVRTLWGNAIYTNVARTDNGDVWWEGLTKQPPAHLIDWKGRDWTPESSEPAAHPNARFTVPAGQCPTIAPEWEDPRGVPISAILFGGRRATAVPLVTEAPDWRRGVFFGSIVASETTAAQAGAIGKLRRDPFAMLPFCGYNMADYFAHWLEVGQKADQTKLPRVYYVNWFRKSPEGRFLWPGFGDNSRVLAWIVGRLEGTAAGVETPLGVLPTKDALPVDGIDIAEEDLETLLTVDVEVWKQEAQLIPEHYQTFGERLPAALWTEHEALVERLNSAD
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMA8_MOUSE
Sequence: MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVKEVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQLLCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHSGILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCEDGDGDSLPGPGLRV
What is the function of this protein?
Functions in nuclear protein import.
What are the official names of this protein?
Importin subunit alpha-8, Karyopherin subunit alpha-7.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Nucleus. Note=In MII-stage oocytes, localizes to the spindle.
Protein: DEF_PELPB
Sequence: MILPINIYSDDILRLKAKPLKGVDSAIEELIASMFESMRNASGIGLAAPQVGRSIRLLVLDVSCVSKCEHEKPMVVINPHILSVRGHNDMEEGCLSVPGVQGYVVRPAAITLKYRDEHFAERTGEFSGMVARVIQHEIDHLDGTLFVDRMEKRDRKKIQKELTALASGIVDTEYPVVEREVVPIAKPT
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: COF_SALNS
Sequence: MARLAAFDMDGTLLMPDHHLGRETIATLARLRERDITLTFATGRHVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASMHVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRIQLNETLEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDREMLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.