PharMolix/UniProtQA huggingface dataset:
Protein: S1PR4_HUMAN
Sequence: MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).  S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.  May be involved in cell migration processes that are specific for lymphocytes.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLK_YERPP
Sequence: MTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTWAFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCVIMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGYELSS
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_SYNP6
Sequence: MPIIIPQDLPARRILDAESVFTLGDADARRQDIRALQVVVLNLMPTKVTTETQIARVLANTPLQVELTLIHTASYQPTHTDPEHLRNFYSTFDQIRDRQFDGLIVTGAPVETLPWLAVDYWSELTTILDWSREAVRSSLFICWGAQAALQHFHGIEKQTLPAKRFGVFWHHLRDRSSPLVRGHDDDFLVPVSRHTEVIAAEVLAQSQLQILAESSEAGLHLLWDADQHRTYLFNHPEYDADTLDREYRRDREKGLPIQLPLNYYPNDDPNQVPTVRWRSHAQLLYTNWLNYEVYQPLSR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_COXB2
Sequence: MAKVCQVTGKRPQSGNNVSHANKKTNRRFLPNLKKRRFWLPDEKRFITLTVSTHGMRIIDKLGINAVLKKIREREKESK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MEIOS_MOUSE
Sequence: MLGSDKFSCFSDQHRARSPSPTDRKDKKNHTNKLRELALLIPVTMKTRDKKYTKKEILLRVLHYIQYLQRNIDMTKALLKLHSSNGKGRFVGPGLNPSAGQTQQQHSTPSSSQKPSLWSTSSKPRKKKFTRVSEHPSWPYNPRRSLALDQAENPNTIHPGLKEENEECATYPGVLSPSTYPTTEPSVSEGDGQGAQLVFLDMAQNIFAYDILSDHAVEVQGGEPNADIKVQRSFFLTRAQPCVSSCRQKLFLCTSSEADKEAPDSDPWLPVWTSEDSPNGSPLALGSSQINTWHVADYLNEILGVSSSLFSSPSKILPDHVLEDGTYFLTEGLLESSPATCEVESPQEKEVSSEGPTGPPNFQSSVSLDHCYLSLSENVKVLSNCGSSSESTDTESLWGQEEVRGVATYPRRTGVFSLAQPSVLQQANPEGLQTSSDEDRDYTWTPTGQSSGLPVASKKIKKVQASQGPVKPKDSRKACPGQVKKKCVNGFIMFCRMNRKQYIRACPGTASTAATKDLAQLWRGMTLEEKKPYCTKARRFSRQNNRIVKQENSSSEDDDGETPKPFYQLLAEKAQVSLGLTSLPTPNCQ
What is the function of this protein?
Gatekeeper of meiotic initiation in both male and female germ cells (PubMed:32032549).  In complex with STRA8, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.  Temporal expression of MEIOSIN is required for meiotic entry decision (PubMed:32032549).
What are the official names of this protein?
Meiosis initiator protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATB_CORDI
Sequence: MTAAMYDLMDYDEVLEKFDPVMGLEVHVELATETKMFSAPSAHFGAEPNSNVDPVSLGLPGALPVVNAKGVEWAIKIGLALNCKIAESSRFARKNYFYPDQPKNYQISQYDEPIAYDGYLDVVLDDGTPWRVEIERAHMEEDTGKLTHLGGADGRIHGATASLVDCNRAGIPLIEIVTKPIEGAGERAPEVARAYVGALRDLVKALGVSDARMDQGSMRCDANVSLRPVGTVEFGTRTETKNINSLKSVEQAVRYEMQRQAQVLEDGGEIVQETRHYQETDGSTSKGRPKETAEDYRYFNDPDLPPVIAPKEWVEEIRATLPELPWIRRARIQKEWGLKDEEMRDLVNAGALDLIVETVEAGASASEARSWWVAYLSQKANESGVELDSLSITPQQVARVAALVKEGKLTNKLARQAVDGVLAGEGDVDEVVAARGLEVVRDDGAIEKAVDEALAANPDIVEKYKAGNTKVTGAIVGAVMKATRGKADPAQVNKLIAEKLA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL2_PARPJ
Sequence: MAIVKVKPTSPGRRAMVKVVNKELHKGKPYAPLLDSQSSTAGRNNNGHITTRHKGGGHKHHYRVVDFRRNKDGIAAKVERLEYDPNRSANIALVLYADGERKYIIAPKGLTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGIYAQVRLRSGEIRRVHVECRATIGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGKTAAGRDPVSPWGTPAKGYRTRSNKRTTSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL10_SHIF8
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LPHI_YERPE
Sequence: MNRVQFNHHHHHHPD
What is the function of this protein?
This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes.
What are the official names of this protein?
his operon leader peptide, his operon attenuator peptide.
What is the protein family that this protein belongs to?
Belongs to the HisL family.
Protein: MOC2A_CHLRE
Sequence: MQIKVLYFAKSREVAGVNEQTFELGDGAHTEDLLAQIIAAHPALDSVMKTCVFALNQEYVRPQDKEALKDGDEVAIIPPLSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APS4_ARATH
Sequence: MASSAAAIVSGSPFRSSPLIHNHHASRYAPGSISVVSLPRQVSRRGLSVKSGLIEPDGGKLMNLVVEESRRRVMKHEAETVPARIKLNRVDLEWVHVLSEGWASPLKGFMRQSEFLQTLHFNSFRLEDGSVVNMSVPIVLAIDDDQKFRIGDSNQVTLVDSVGNPIAILNDIEIYKHPKEERIARTWGTTARGLPYAEEAITKAGNWLIGGDLQVLEPIKYNDGLDRFRLSPSQLREEFIRRGADAVFAFQLRNPVHNGHALLMTDTRRRLLEMGYKNPVLLLNPLGGFTKADDVPLSWRMRQHEKVLEDGVLDPETTVVSIFPSPMLYAGPTEVQWHAKARINAGANFYIVGRDPAGMGHPTEKRDLYDADHGKKVLSMAPGLERLNILPFKVAAYDKTQGKMAFFDPSRSQDFLFISGTKMRGLAKKKENPPDGFMCPSGWKVLVDYYDSLSAETGNGRVSEAVASA
What is the function of this protein?
Sulfate adenylyltransferase.  Catalyzes the first step of the sulfate assimilation pathway.
What are the official names of this protein?
ATP sulfurylase 4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: 6PGL_NOSS1
Sequence: MKKTVEVLPDQTALIARSLDLILTKLDTAIKQQGRFTIALSGGSTPKPLYEAIAAQKLPWDKIHVFWGDERYVSPDHPDSNELMARTAWLDRVDIPAENIHAVPTLDNNPAVSAAKYEQHLQTFFNSAPGEFPALDVVLLGMGDDAHTASLFPHTEALQVRDRLITVGNKDGNPRITFTYPFINAASSVIFVVAGANKRPALAQVFAPSADDLAYPSRFIQPQGELLWLLDAAAGAELSV
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: IF1_LACH4
Sequence: MAKDDVIEVEGKVVDTLPNAMFKVELENGATILAHVSGKIRMHYIRILPGDRVTVELSPYDLTKGRITYRFIK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_BARQU
Sequence: MVMTRRIFFSWFIVICSLWLSSFSSVHAKLKGTISSADFNPIPIAITDFVSNDSIGLKIAAVVTADLERSGLFLPLDKASFFEKISNPNSQPHFFHWQKIRAQGLVTGQVIRENDGRLRVDFRLWDVFGHQQLKGRRFYTATERWRRVAHMIADEIYSEMTGESGYFDTRIVFIDETGPQNARIKRLAIMDQDGANLIYISDGSELVLTPRFSPKRQEITYMAYERNQPPHVYLQQIEMGQRELIGTFKNMTIAPRFSSDGQKVIMSLLQNNGSANLYTMDLRTRMMTRLTTTSAIDTSASYSPDGTQIVFSSDRSGKPQIYTMNADGSNLQRISANEGSYSTPIWSPRGDYIAFTKQLEGQFSIGVMRPDGKGERILTTGFHNEGPTWAPNGRVLMFFRKNPGMGPKIYTIDITGRNERQLPTPNDASDPAWSPLLNMQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: P121B_HUMAN
Sequence: MSRRVRTSELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK
What is the function of this protein?
Putative component of the nuclear pore complex (NPC).  The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane (By similarity).
What are the official names of this protein?
Putative nuclear envelope pore membrane protein POM 121B.
What is the protein family that this protein belongs to?
Belongs to the POM121 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: DUT_SHIF8
Sequence: MKKIDVKILDPRVRKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GLYA_STRP7
Sequence: MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQANCAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAILKQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPVPYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFKEVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQNLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITAREFGEEESRKVAELIIKTLKNSENEAVLEEVRSAVKELTDAFPLYEE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URM1_PICST
Sequence: MGFKVKVEFLGGLDVISNKVREHSLKVPLEEGEATVKDLIELITKSIIADPKDIPVFIEDDTVRPGILVLINDTDWELEGMEEYVLESGDVFTFTSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_SYNY3
Sequence: MDGSYAASYLPWILIPMVGWLFPAVTMGLLFIHIESEGEG
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: LPQB_MYCBO
Sequence: MERLMRLTILLFLGAVLAGCASVPSTSAPQAIGTVERPVPSNLPKPSPGMDPDVLLREFLKATADPANRHLAARQFLTESASNAWDDAGSALLIDHVVFVETRSAEKVSVTMRADILGSLSDVGVFETAEGQLPDPGPIELVKTSGGWRIDRLPNGVFLDWQQFQETYKRNTLYFADPTGKTVVPDPRYVAVSDRDQLATELVSKLLAGPRPEMARTVRNLLAPPLRLRGPVTRADGGKSGIGRGYGGARVDMEKLSTTDPHSRQLLAAQIIWTLARADIRGPYVINADGAPLEDRFAEGWTTSDVAATDPGVADGAAAGLHALVNGSLVAMDAQRVTPVPGAFGRMPEQTAAAVSRSGRQVASVVTLGRGAPDEAASLWVGDLGGEAVQSADGHSLLRPSWSLDDAVWVVVDTNVVLRAIQDPASGQPARIPVDSTAVASRFPGAINDLQLSRDGTRAAMVIGGQVILAGVEQTQAGQFALTYPRRLGFGLGSSVVSLSWRTGDDIVVTRTDAAHPVSYVNLDGVNSDAPSRGLQTPLTAIAANPSTVYVAGPQGVLMYSASVESRPGWADVPGLMVPGAAPVLPG
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: YCIB_PHOLL
Sequence: MKQLLDFLPLVVFFVVYKMYDIFYASGALIAATGLAVAMTYFIYRKVEKASLITFIMVAVFGTLTLAFHSDLFIKWKVTVIYALFALALLGSQWFMKKPLIQKMLGKELILPDLVWNKLNMAWALFFTACALANIYVAFWLPQDVWVNFKVFGLTALTLVFTVLSVVYIYRHLPREQK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQO1_THET8
Sequence: MTGPILSGLDPRFERTLYAHVGKEGSWTLDYYLRHGGYETAKRVLKEKTPDEVIEEVKRSGLRGRGGAGFPTGLKWSFMPKDDGKQHYLICNADESEPGSFKDRYILEDVPHLLIEGMILAGYAIRATVGYIYVRGEYRRAADRLEQAIKEARARGYLGKNLFGTDFSFDLHVHRGAGAYICGEETALMNSLEGLRANPRLKPPFPAQSGLWGKPTTINNVETLASVVPIMERGADWFAQMGTEQSKGMKLYQISGPVKRPGVYELPMGTTFRELIYEWAGGPLEPIQAIIPGGSSTPPLPFTEEVLDTPMSYEHLQAKGSMLGTGGVILIPERVSMVDAMWNLTRFYAHESCGKCTPCREGVAGFMVNLFAKIGTGQGEEKDVENLEALLPLIEGRSFCPLADAAVWPVKGSLRHFKDQYLALAREKRPVPRPSLWR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.  The Nqo1 subunit contains the NADH-binding site and the primary electron acceptor FMN.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 1, NADH dehydrogenase I chain 1, NDH-1 subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CPRF2_PETCR
Sequence: MDRVFSVEDISDQFWSPPAREDSSKLVMNRSDSEWAFQSFLQQASALESSQPLPSDPVPVAGDVKNPVEIPANVPVDSEDYQAYLKSRLDLACAAVALTRASSLKPQDSAALLDNGSQASNTSQLVSQVPPKGSGHDLSKEEDKEALAATATPLLPALQKKSAIQVKSTTSGSSRDHSDDDDELEGETETTRNGDPSDAKRVRRMLSNRESARRSRRRKQAHMTELETQVSQLRVENSSLLKRLTDISQRYNDAAVDNRVLKADIETMRAKVKMAEETVKRVTGLNPMFQSMSSEISTIGMQSFSGSPSDTSADTTQDGSKQHFYQPAPTSHMPAQDQKIQNGLLQVPPVDNLQQHSASGPVEGNKMERTSSMQRVASLEHLQKRIRGGVSSCEAQVSGKQ
What is the function of this protein?
Binds to the G-box-like motif (5'-ACGTGGC-3') of the chalcone synthase (CHS) gene promoter.  G-box and G-box-like motifs are defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control.
What are the official names of this protein?
Light-inducible protein CPRF2, Common plant regulatory factor 2, CPRF-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM6_IDILO
Sequence: MHNDYLKQVKSYLMSLQDAICQQLAQADGEQSFQEDSWDRPGGGGGRSRIMKNGAVFEQGGVGFSHVYGEKMPASATAHRPELEGRDFNACGVSLVMHPENPMVPTVHMNVRFFIAQKEGEEPVWWFGGGFDLTPFYPFDQDIIEWHQQAKNALDSVDEKLYPEYKAWCDDYFFLKHRDEARGVGGIFFDDLNDRSFDECFSVIKAVGDAFTKAYLPIVERRKNLAYTQQQRDFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLARWEYNWQAEPGSAEEQLTEYYLKPRDWLSV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_AQUAE
Sequence: MAEKKEKIIGIDLGTTNSVVSVMMGDEAVVIQNQEGSRLTPSVVSWTKEKEILVGEPAKRRAILDPENTVYESKRFIGRKFEEVKEEAKRVSYKVVPDEKGDAAFDIPNAGKLVRPEEVGAHVLRKLKEAAEAFLGEPVKKAVITVPAYFNERQRQATKDAGKIAGLEVVRILNEPTAAAMAYGLHKKDNVRILVYDFGGGTFDVSILEGGEGVIEVKVTAGDTHLGGANIDERIMDWLIEEFKKETGIDLRKDRTALQRLKEASEQAKKELSFKMETEINLPFITIDPNTNQPLHLQKKLTRARLEEMIKDIVDRTIDIVKQALEDAKLKPSDIDEVVLVGGSTRIPLVQQRIKEFFGKEPHKGLNPDEVVAMGAAIQAGVLAGEVKEIVLVDVTPLSLGVETYGGVMTVLIPRNTPIPVRKCEIFTTAHDYQTEVEIHVLQGERPLAKDNKSLAKFYLTGIPPAPRGVPKIEVCFDIDADGILHVTAKDLGTGKEQSVRVEISSGLTPEEIERIIKEAEEHAEEDRKKKELIEAKNQLDHLVYQLEKALKEAGDKVPADVKSEAEKVIEEAKKTIETATEIEQVKQVTEKVLQVSSKMGTTLYGEAGKQAGGGEKKDEGGEGEVEAKPVD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL16_HISS2
Sequence: MLQPKRTKFRKVHKGRNRGIAAGTEVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVMYEMDGVSEEVARHAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CATZ_ONCVO
Sequence: MLAILFNFFLLTYFTNITLGKVGKSIDLDTRNGYNVHGCYKQTGKIYAHKTYPRQYEAENYNFDDLPVAWDWRNINGVNYASVDRNQHIPQYCGSCWAFGSTSALADRFNIKRKGAWPPAYLSVQEVIDCANAGSCEGGEPGPVYKYAHEFGIPHETCNNYQARDGTCSSYNKCGSCWPGSCFSIKNYTIYRVKNYGAVSGLHKMKAEIYHHGPIACGIAATKAFETYAGGIYNERTNEDIDHIISAHGWGVDSESGVPYWIGRNSWGTPWGENGWFRIVTSEYKNSSSKYNLKIEEDCVWADPIA
What is the function of this protein?
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity).  Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed (Probable) (PubMed:15555728).  Required for the degradation and shedding of the old cuticle (Probable) (PubMed:15555728).
What are the official names of this protein?
Cathepsin Z, L3 cysteine protease, LOVCP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Localizes in secretory vesicles in the hypodermis of L3 larvae.
Protein: HAS1_COCIM
Sequence: MPVTMETSKEHSKKRKRKHGGSGNAALTSANAAKSLVKTTLSSKGEASAEKQEMKKRKTEHPSLMEDRVSENVVDEPEEVVEEDSEASQPPVEQDDEQKSESEQQPELPSLNALSLPQTENEPQKFTELNLSEKTLKAIQEMGFETMTEIQRRGIPPLMAGRDVLGAAKTGSGKTLSFLIPAVEMLSALRFKPRNGTGVIVVSPTRELALQIFGVARELMAHHSQTYGIVIGGANRRAEAEKLTKGVNLLIATPGRLLDHLQNTDGFVFKNLKALVIDEADRILEVGFEDEMRQIVKILPSEDRQTMLFSATQTTKVEDLARISLRPGPLYINVDHRKEHSTVEGLEQGYVICDSDKRFLLLFSFLKRNLKKKIIVFFSSCNCVKYHAELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKQGTLICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGANGKGRSLMFLQPSEVGFLKHLKDARVPVVEFEFPAKKIVNVQSQLEKLIGQNYYLNKSAKDGYRSYLQAYASHSLRSVFDVNKLDLVKVAKGFGFPTPPRVDISLGASMSRDKKQTSRRNYGSQPRHAPKFKRKTSDD
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.