PharMolix/UniProtQA huggingface dataset:
Protein: KCY_CUPMC
Sequence: MTIVDVITIDGPTASGKGTVAHKVADALGFHLLDSGALYRLVALASDRAGVGVQDVDTLAKMAARLDVKFGPDRVWLSGEEVSQTIRLEAIGNRASAIAVHQPVRDALTALQRGFRKLPGLVADGRDMGTVIFPDAPLKVFLTASVEARARRRYKQLIDKGISANIEDLLRDLEERDARDRTRAAAPLRPAEGAYRLDTSEMTVEEAVAQVLEWFAAVR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HVM24_MOUSE
Sequence: EVKLVESGGGLVQPGGSLRLSCATSGFTLSDFYMEWVRQTPGKRLEWIAASRNKVYDYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCARDAYYGSYWYFDVWGAGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region HPCG13.
Protein: PGK_CAMJE
Sequence: MSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILASHLGRPKEISSKYSLEPVAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEIDFASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNSLLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPMKFVPAQEIPNGWMGLDIGPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y851_STAAW
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHKMFWITMALIIITMVLGVILPLGPISKLFGIG
What are the official names of this protein?
UPF0344 protein MW0851.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1789_COXBN
Sequence: MSITQWPTSERPREKLLREDAHILSDAELIAVIIQKGVRGCNAVELAREWLNHLGGLASLLNADFHRLSGLRGLGKAVYCKLKAAAELQRRYLRQSLERKGQLGCTQDAQQLLYAQLRHHESEVFACLFLDNRHRIIQFEKLFYGSINQASVHPREIIKRALYHNSAALIVAHNHPSGVPDPSQADRAATTHLKEALALIDVRLLDHIIIGDRNSFSFAESGLL
What are the official names of this protein?
UPF0758 protein CBUD_1789.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: AROC_CLOTE
Sequence: MERYTMLRFLDAGESHGKAMMSIIDGIPSNFKVDIDFINNELKRRQKCYGRGGRMKIEKDKIQFLSGLRGTMTTGNPITMAIYNNDSPNWEKILSGEVKKDEKITIPRPGHGDLVGYFKYGTGDIRDSIERTSARETSIRTAVGALCKQILKGIGIEVRSKVYSIGNLFDEKVDLFDQCKYKKIDNSLLRCYNEEVEKSFVKKIDICREQGETIGGTVFLSVRGVPIGLGSYSQWDRKLDALLSYAIMSLQGVKAIEFGNGMNLNLRGSTFNDEILYEKGKFKRPTNNCGGIESGVSNGENIEMKVYIKPIPSIKKNIRTVNLRNRKETTTRYERSDVSAVVPASIVLENIVAFEILKEILNKFPSDEYYELKRNISHYRGTIYLR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: YL072_MIMIV
Sequence: MNNIRPKYYAFYNKISEGYYNPLYRKGLNKDTIYEIMVEDGFPTEKNVSFVSIENIFQQINFGSHIAEVFVPGYVKTSYNETTLKHYADMCIIGDIMNFYDINTIRYLIDNGANIKNCGNLLCQASQLGCIDIVKLLVKTSEKEFSGMDDLTRSNKLISTQEIFTDFKNNDHNVCILIAIVYKHIDVVKYFISIGEILSVKDDSLYFKLACDTGCLNIIKYLLEIGFDIESNNNYCLMISTINGRNDIVEYIKSRGVNPNNHVKKCIQIITNHNDDLKSSDIFLMTKFIKTTGVNSNILYQLLLIACEYGYYSMTMYLIKAGIKPTNSCLKIACKNNKFNIVKLITKYPKTRLDINVDNNYCMKQAIFHKNKDMVDYLTNFKYV
What are the official names of this protein?
Putative ankyrin repeat protein L72.
Protein: VM2_GLOHA
Sequence: EAGEECDCGAPANPCCDAATCKLRPGAQCAEGLCCDQCRFMKEGTICRMARGDDMDDYCNGISAGCPRNPFHA
What is the function of this protein?
Inhibits fibrinogen interaction with platelets by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3).  Also inhibits ADP-induced platelet aggregation.  Inhibits basic fibroblast growth factor (bFGF)-induced proliferation of human vascular endothelial cell (HUVEC), and vitronectin-induced migration of smooth muscle cells (SMC).  It also regulates platelet activation associated with HUVEC migration and invasion, suppresses TNF-alpha-induced ovarian cancer cell proliferation and invasion, and inhibits angiogenesis and tumor progression.
What are the official names of this protein?
Disintegrin saxatilin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: E2F1_MOUSE
Sequence: MAVAPAGGQHAPALEALLGAGALRLLDSSQIVIISTAPDVGAPQLPAAPPTGPRDSDVLLFATPQAPRPAPSAPRPALGRPPVKRRLDLETDHQYLAGSSGPFRGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSRSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTMVGIGKRLEGLTQDLQQLQESEQQLDHLMHICTTQLQLLSEDSDTQRLAYVTCQDLRSIADPAEQMVIVIKAPPETQLQAVDSSETFQISLKSKQGPIDVFLCPEESADGISPGKTSCQETSSGEDRTADSGPAGPPPSPPSTSPALDPSQSLLGLEQEAVLPRMGHLRVPMEEDQLSPLVAADSLLEHVKEDFSGLLPGEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF
What is the function of this protein?
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:11672531, PubMed:20176812, PubMed:9674698).  The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase (By similarity).  E2F1 binds preferentially RB1 in a cell-cycle dependent manner (By similarity).  It can mediate both cell proliferation and TP53/p53-dependent apoptosis (PubMed:9674698).  Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:11672531, PubMed:20176812).  Directly activates transcription of PEG10 (By similarity).  Positively regulates transcription of RRP1B (By similarity).
What are the official names of this protein?
Transcription factor E2F1, E2F-1.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FETP_SHEPW
Sequence: MARTVNCVYLKKEAEGLGFQLYPGDLGKRIFDNVSKEAWALWQSKQTMLINENKLNMMNVDDRKFLEEQMINFLFEGKDVEIEGYVPQKDDE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CYSD_PSEP1
Sequence: MVDKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTQWKFQEMYSFRDKMVEEMGLELITHVNPEGVAQGINPFTHGSSKHTDIMKTQGLKQALDKHGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNVYNGKVNKGESIRVFPLSNWTELDIWQYIYLEGIPIVPLYFAAEREVIEKNGTLIMIDDERILEHLSEEEKARIVKKKVRFRTLGCYPLTGAVESEAETLTDIIQEMLLTRTSERQGRVIDHDGAGSMEDKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL3_METPB
Sequence: MRSGVIARKVGMTRVFTDAGEHVPVTVLQIDQCQVVAHRTTEKDGYVALQVGVGKAKVKNVSQAERGRFAVAKVEPKKKLAEFRVSEDALIPVGAEITADHFIPGQFVDVTGTTTGKGFAGGMKRWNFGGLRATHGVSISHRSIGSTGGRQDPGKTFKNKKMPGHLGVERVTTQNLKVVRTDPERGLILVEGAVPGVAGGWIQVRDSVKRKLPADVPLPGKFRENGSAGASQVEAAPEAPASEENA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: AGRL3_HUMAN
Sequence: MWPSQLLIFMMLLAPIIHAFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSELERPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTHLPSASSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEALSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIASGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNLMNKLVNNLGSGREDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYTRRRIPQDHSESFFPLLTNEHTEDLQSPHRDSLYTSMPTLAGVAATESVTTSTQTEPPPAKCGDAEDVYYKSMPNLGSRNHVHQLHTYYQLGRGSSDGFIVPPNKDGTPPEGSSKGPAHLVTSL
What is the function of this protein?
Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:26235030).  Plays a role in the development of glutamatergic synapses in the cortex.  Important in determining the connectivity rates between the principal neurons in the cortex.
What are the official names of this protein?
Adhesion G protein-coupled receptor L3, Calcium-independent alpha-latrotoxin receptor 3, CIRL-3, Latrophilin-3, Lectomedin-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell junction.
Protein: Y2838_ENT38
Sequence: MEMTNAQRLILSNQYKMMTMLDPDNAERYRRLQTIVERGFGLQMRELDREFGELKEETCRTVIDIMEMYHALHVSWTNLKDAQTIDERRVTFLGFDVATESRYLSYVRFMVNTEGRYTHFDAGTHGFNSQTPMWEKYQRMLSVWHSCPRQYHLSSNEIQQIINA
What are the official names of this protein?
UPF0304 protein Ent638_2838.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: TOLB_SHIB3
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPSAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ERPA_VIBC1
Sequence: MSEVNVPLSFSDAAASRVKALIAEEENPALKLRVYITGGGCSGFQYGFTFDERVNEGDTTIVNSGVTLVVDPMSLQYLIGGVVDYTEGLEGARFFVNNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PQBP1_GORGO
Sequence: MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDKSDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD
What is the function of this protein?
Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development.  Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species.  May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner.  Can activate transcription directly or via association with the transcription machinery.  May be involved in ATXN1 mutant-induced cell death.  The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.  Involved in the assembly of cytoplasmic stress granule, possibly by participating in the transport of neuronal RNA granules.  Also acts as an innate immune sensor of infection by retroviruses, by detecting the presence of reverse-transcribed DNA in the cytosol.  Directly binds retroviral reverse-transcribed DNA in the cytosol and interacts with CGAS, leading to activate the cGAS-STING signaling pathway, triggering type-I interferon production.
What are the official names of this protein?
Polyglutamine-binding protein 1, PQBP-1, Polyglutamine tract-binding protein 1.
Protein: ATPF_HALH5
Sequence: MFDINWGSIIYQLIAFCVLLWLLSKFALKPLMGVMEKREQMINDQIDQADKDRKAAQEYLEQQRLAVEKAREEAQEIVQKAKKLSEQQGQEIVEAARAEGERLKEAALAEIQREKEQAVASLREQVASLSVLIATKVIEKELDEKEQEKLIAEYLKEVGEEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
Protein: RS21_LACLM
Sequence: MSKTLVRKNESLDDALRRFKRSVTKAGTLQELRKREHYEKPSVKRKRKSEAARKRKKY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RPOC1_DRANE
Sequence: MIDRYKHQQLRIGLVSPQQISAWATKKIPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRIRRYQMGYIKLTCPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPITKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDIFRNREISTGAGAIREQLADLDLRIIIENSLVEWKQLGEEGPTGNEWEDRKIVRRKDFLVRRMELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIEGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHLASNIGVAKSQIREKKPIVWEILQEVMQGHPVLLNRAPTLHRLGIQSFQPILVEGRTICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSGTRRGICANRYNPCNRKNDKNEKLYETNYKYMKEPFFCNSYDAIGAYRQKRINLDSPLWLRWQLDQRVIASREVPIEVHYESFGNYHEIYAHYLIVRSVKKETFCIYIRTTAGHISFYREIEEAIQGFSQACSYDT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CARB_BACC1
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQDLNEPTPPSEIIHNLDEAYSFVNEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQTAKEMGFSDHYIAAAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFESATPYYYSTYAEENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFENQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: SYFA_BLOFL
Sequence: MPKKLLINLVKQAKLSLEQSNTIQDVESIRIQFLGKHGYINQQLKKINSLNWDNKSKIGTVINQVKSDIHQLFLERKKLITLKAIEKSLNTEKLDITLPGRLSETGTIHPITNTINRIRLFFNHLGFKEIYGPEIENSYFNFDSLNIPNNHPSRDQHDTFWFDTNKLLRTHTSGIQIRAMKHIPMPIQIISIGKVYRKDYNKEHTPMFHQIEGMMISSNINLTNLKKILYDFLYNFFGKNVILRFRASYFPFTEPSAEIDILNLNINNKKQPKKWIELLGCGMIHPTVLNNGGIDSKKFSGFAFGIGIERLTMLLYHMTDIRVFFENDLQFLDQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLF5_HUMAN
Sequence: MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
What is the function of this protein?
Transcription factor that binds to GC box promoter elements.  Activates the transcription of these genes.
What are the official names of this protein?
Krueppel-like factor 5, Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, Transcription factor BTEB2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YVDA_VACCC
Sequence: MAPLFSSKKFFVDGLSSIVDAPLINFLLRSIIVAKSTLSTRTNPYSLNTLTISFFLIMYSVIGVDIVDGLYTTILSSAIFSTDI
What are the official names of this protein?
Uncharacterized 9.2 kDa protein.
Protein: RL10_METBU
Sequence: MAELHHSEHIPQWKKDEIEEIKSLIESYPLFGVIGIEGIPAKQLQSMRRDLKDFAVLKVCRNSLTRRALDQSSDDVKKMDDYIDVQTALIFTKQNPFKLYKLLEKSKTPSPIKAGMVATSDIIVEKGPTSFPPGPILGDMQGAGIPAAIDGGKVVIKETKAVAKAGEVVSQKLAAMLTRLEIYPLEVGLDLRAVLEEGSIFTPDVLAIDEEQIFSNFVQAAQQAFNMSVNAAYPTAMNINTLLAKAASDSRNVAVNATVYEPGIMDILLGKAYSKMMAIASAASSNDDALDDELKEALGAASSAVSAVEEVVEEQEEVKEEEEEESDMASGLGALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL24_ECO7I
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SECU_YEAST
Sequence: MMPANEDKENNIVYTGNESSGINFPQTPAHLLKRSHSNILKPPVRLDQLKRDANSNNGNTLKYIQGGKEVSPTKRLHTHAQQQGRLPLAAKDNNRSKSFIFPETSNQSKDADLPQLQNTLSIRKNDQLRKLSQISRSRSRANHNDLLSNSRKLQKYGSVLGYNALPKMKSLVLKDLADSGKNEESSDDDEGNEDSESKLGKKLQSALLKQDSSDGENELNGGLGLFNEQGGLQQLIKNSTKNEQKTKNDKSDKTDDYDIEIAPQRQEPLPYVPEGYSPFQQDDIEKLKTFNSPYKLDLEDEDDTPDKVDLLPLEQIDEEGEKDETECITRNQEEGAALPLLSKNFKEVAAVPTMELVYSEEGLDPEELEDLVT
What is the function of this protein?
Regulatory protein, which plays a central role in chromosome stability.  Probably acts by blocking the action of key proteins.  During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.  At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
What are the official names of this protein?
Securin.
What is the protein family that this protein belongs to?
Belongs to the securin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KAX6C_ANUPH
Sequence: QKECTGPQHCTNFCRKNKCTHGKCMNRKCKCFNCK
What is the function of this protein?
High affinity blocker of Kv1. 3/KCNA3 channels of human T cells.  Blocks Kv1. 2/KCNA2 with an order of magnitude smaller than for Kv1. 3/KCNA3.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.12, Anuroctoxin.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RECU_LEUMM
Sequence: MTINYPVGTHHGKTLKNNTLRTGKTTKKVLFGKRGMGLEDEINLANDYYLANRLAVVHKKPTPITIVKVDYPARSAAKITEAYFKQASTTDYNGVYQGKYIDFDAKETKNKTSFPLKNFHEHQISHLASILSQGGIGFVIIKFTSLNENYVYPASELIQQWQHLNGKQSISYQEIVDKSFVVPESLNPSLDYLTAVDKMLEALH
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_YERE8
Sequence: MYHDLIRSELNEAADTLANFLKDDDNINAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFSRYVEAVGREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_BUCAT
Sequence: MLEKKTNTEFLVLSTTNTQDKNIKQPLCELVKKSLKYYLSNLNGKDVNNLYELALSELEQPLLDMIMQYTRGNQTRAALMLGINRSTLRKKLKKYSMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.