PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_OENGL
Sequence: MKNVTDSFVSLVHWPSAGSFGFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILNTIRNSEELREGAIEQLEKARARLQDVQIEAEGYRAYGYFGIDEQRHESINSTYKTLEQLENNKNESIHFEQQRAINQVRQQIFQQALQGALGTLNSCLNNELHLRTISANIGLFGSMKELTD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GSTF3_ARATH
Sequence: MAGIKVFGHPASTSTRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLPADSKNIAQYAIMSIGIQVEAHQFDPVASKLAWEQVFKFNYGLNTDQAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPVIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVL
What is the function of this protein?
Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3-aldehyde.  May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase F3, AtGSTF3, GST class-phi member 3, Glutathione S-transferase 16.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: AKT3_HUMAN
Sequence: MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
What is the function of this protein?
AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis.  This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates.  Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported.  AKT3 is the least studied AKT isoform.  It plays an important role in brain development and is crucial for the viability of malignant glioma cells.  AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13.  Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands.  Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.
What are the official names of this protein?
RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Protein: DRTS_CRIFA
Sequence: MSRAAAKFKIPMPVTKADFAFPSLRAFSIVVAADQQHGIGDGETIPWTVPETLAFFKDQTTLLRNKKPPTEKKRNAVVMGRKTWEVPLKFRPLKGRLNVVLSCRRPVDDLLAQLPEEKRAAAAADVVINGGLKEALHLLARPPYCSSIETAYCIGGARVYTEAMQSPCVEKLKEVYLTRVHTAPTCNRFYEFVRRRRARAAVDLESTSGVKVSDAAAHLSYEIMKYVPHNAEERQYLELIDRIMKTGLVKEDRTGVGTISLFGAQMFSLRDNQLPLLTTKRVFWRGVCEELIWFLRGETNAHVLADKDIHIWDGNGSREFLDSRGLTENKEMDLGPVYGFQWRHFGADYKGFDANYDEGVDQIKTIVETLKTNDRRLLVTAWNPCALHKMAVRPCHLLGQFYVNTQTKELSCMLYQRCCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGTAHVYSNHVEALKEQLQRVPVAFPVLVFKKEREFLEDYESTDMEVVDYVPYPPIKMEMAV
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: ACYP_LISMO
Sequence: MARDTAILRVTGFVQGVGFRYTTKHVAYKYDISGTVKNLDDGSVEIHAIAEEENLNKFIDAIKKGPSPGCRIEHVYIYKGAPVEERKTFDIVY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: FRAT1_MOUSE
Sequence: MPCRREEEEEAGDEAEGEEDDDSFLLLQQSVTLGGSTDVDQLIVQIGETLQLDAAHDRPASPCAAPGPPPPQVLAALPADKTGTPARRLLRPTGSAETGNPAPPGAVRCVLGERGRVRGRSAPYCVAEISPGASALPQQPGLDGPPGTGKLSTPQPLSGPCRRGWLRNAAASRRLQQRRGSQPETRTGDDDDPHRLLQQLVLSGNLIKEAVRRLHSRQLQLHAKLPAHPFLGPLSAPVHEPPSPGSPRAACSDPGAFMGRAQLRTGDDLLVPGS
What is the function of this protein?
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.  May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
What are the official names of this protein?
Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1.
What is the protein family that this protein belongs to?
Belongs to the GSK-3-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_RUTMC
Sequence: MNIILLGPPGAGKGTQATNICQKYSIPQISTGDMLREAVKADTPLGIEAKKVMDVGGLISDDIIIGLVKERIQENDCKNGFLFDGFPRTIVQAEALKTDGVKIDFVVEIQVPYEDIIARMSGRRAHLTSGRTYHIVYNPPKVEGIDDITGEELIQRTDDAEDTVRARLNIYHKQTKPLVDYYQSWMNKNSDAPKYGAVVGVGTLDEVRDRVYAQLN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_VIBVU
Sequence: MNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELMRNEKSGMGQLTRQETQGLSPEICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLGDIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWMNHKPMLVAELFLPDAPIYSRESV
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACAH
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYTLHTSYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y4QD_SINFN
Sequence: MREVQSLGIVITDPQQMISTCKRRFSAALGVVGGTSVLRRLLSQLAHAGVQRTMVLARETLGEIAGDLGGELNGMELCLRALPRPNAGRLVDAATANEIAHVDGDVLVFTENLVIDFDVIERLLRSQDRNIAVVSKTQGGRSLRVLADDALRLTAVLPDRPSSQHHASADWNLMGVYKFDPAFVRAIARNRRYRAHDDLEFFETALGIHAHPMHLMCAEPQRVRTVNDAVDLAAANYAFRSSSD
What are the official names of this protein?
Uncharacterized protein y4qD.
Protein: A52_VACCW
Sequence: MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMFTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS
What is the function of this protein?
Bcl-2-like protein which targets host toll-like receptor signaling complexes to suppress innate immune response.  Interacts with host TRAF6 to activate p38 and subsequently induce the expression of several cytokines such as IL-10.  Associates also with host IRAK2 to inhibit NF-kappa-B signaling.
What are the official names of this protein?
Protein A52.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus A52R protein family.
Protein: APBP2_RAT
Sequence: MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITSGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSTGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVNSSPQSTEEVVQSFLMSQNVEGPSC
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(APPBP2) complex specifically recognizes proteins with a -Arg-Xaa-Xaa-Gly degron at the C-terminus, leading to their ubiquitination and degradation.  The CRL2(APPBP2) complex mediates ubiquitination and degradation of truncated SELENOV selenoproteins produced by failed UGA/Sec decoding, which end with a -Arg-Xaa-Xaa-Gly degron.  May play a role in intracellular protein transport: may be involved in the translocation of APP along microtubules toward the cell surface.
What are the official names of this protein?
Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Associated with membranes and microtubules.
Protein: RPOB_YERPA
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFQKFIEQDPEGQHGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITARHIRQLEKDGIDRIEVPVEYIAGKVVAKDYVDASTGELICAANMELSLDLLAKLSQAGHKQIETLFTNDLDHGAYISETLRVDPTSDRLSALVEIYRMMRPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKEDITEVMKKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVRDGVVTDEINYLSAIEEGNFVIAQANSNLDDEGRFLEDLVTCRSKGESSLFSREQVDYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTSVAKRGGTVQYVDASRIVIKVNEDEMHPGEAGIDIYNLTKYTRSNQNTCINQMPCVNLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLTEELQILEAGLFARIHAVLVSGGIEAEKLSKLPRERWLELGLTDEDKQNQLEQLAEQYDEMKSEFEKKMDAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKKQEEVAKLREFIQKAYDLGDNVCQKVDLSTFTDDEVLRLAENLKKGMPIATPVFDGATEKEIKELLQLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GLMU_ECOLC
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBP1_DANRE
Sequence: MASTCSGCGPGYKTPLDAMKGPREEIVYLPCIYRNTDIQKPDYLATVDINPQSPNFCKVIHRLPMPNLKDELHHSGWNACSSCFDDPSKRRNRLILPSLISSRIYVVDVGTDPRAPRLHKTVEPTDLFWKCGLANPHTSHCLGSGQIMISTMGDPSGNGKGGFVLLDGETFEVIGNWEQPGDAAPFGYDFWYQPRHNVMISTEWGAPKALGNGFNPADVKAGHYGQRLHVWDWTTHKRIQTLDLGEEGAIPLEVRFLHDPAAAEGFVGCALQSTVFRFYKTPKGDWAAEKVIKVPSKKVEGWALPDMPGLITDILISLDDRFLYFSNWLHGDIRQYDITDRKNPRMVGQVFLGGSVLKDGPVKVLEDKELDSQPTPRILKGKRLYVTTSLYSAWDKQFYPDLIKEGSVMMQIDVNTDTGGLKLNENFLVDFGAEPEGPALAHELRYPGGDCTSDIWL
What is the function of this protein?
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (By similarity).  Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm.  May be involved in intra-Golgi protein transport (By similarity).
What are the official names of this protein?
Methanethiol oxidase, MTO, Selenium-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the selenium-binding protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: LCRV_YERPS
Sequence: MIRAYEQNPQHFIEDLEKVRVEQLTGHGSSVLEELVQLVKDKNIDISIKYDPRKDSEVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQLQNGIKRVKEFLESSPNTQWELRAFMAVIHFSLTADRIDDDILKVIVDSMNHHGDARSKLREELAELTAELKIYSVIQAEINKHLSSGGTINIHDKSINLMDKNLYGYTDEEIFKASAEYKILEKMPQTTIQEGETEKKIVSIKNFLESEKKRTGALGNLKDSYSYNKDNNELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLLDDTSGK
What is the function of this protein?
Involved in calcium regulation of yop expression, which includes the export process.
What are the official names of this protein?
Virulence-associated V antigen, Low calcium response locus protein V.
What are the subcellular locations of this protein?
Secreted.
Protein: MVK_THEON
Sequence: MRVLASAPAKIILFGEHSVVYGKPAIAAAIDLRTYVWAEFNNKGAIKIEAKDIKVPGLTVSFSEDEIYFESDYGKAAEVLSYVRQAIELVREEADKNGNGVTVSITSQIPVGAGLGSSAAVAVATIGAVSRLLGLELSNEEIAKLGHKVELLVQGASSGIDPTVSAIGGFLHYEKGNFEHLPFMELPIVVGYTGSSGSTKELVAMVRRNYEEMPEVIEPILVSMGKIVEKAKDVLLSELDNEVRFVQLGRLMNINHGLLDALGVSTKKLSELVYAARTAGALGAKITGAGGGGCMYALAPEKQSEVATAITIAGGTPMITKISDEGLRIEEVLP
What is the function of this protein?
Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP).  Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
Mevalonate kinase, MK, MVK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLP4_ORYSJ
Sequence: MAGVWVFEDGMVRRADSEAPSRGRGVGGGGGGGKVLVHVPSSEVVTSYEVLERRLRELGWERYLNDPCLLQFHQRSTVHLISVPRDFSRLKLVHMYDVVVKTRNVFEVRDAATTASPP
What are the official names of this protein?
Flowering-promoting factor 1-like protein 4, FPF1-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the FPF1 family.
Protein: CYB_LEPRA
Sequence: MTNTRKNHPLMKIINNSFIDLPTPPNISSLWNFGSLLGACLTIQVITGLFLAMHYTADTTTAFSSVTHICRDVNYGWTIRYLHANGASMFFMCLFIHVGRGLYYGSFALLETWNIGIMLLFSVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTNLVEWIWGGFSVGKPTLTRFFALHFILPFIISALAMIHLLFLHETGSNNPLGMSSNSDKIPFHPYYTTKDFLGLLLLILLLMTLTLFYPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALILSILILAIIPFLQPSKQQTMMFRPLSQFLFWILVADLLTLTWIGGQPVENPFISIGQTASILYFSLMVFIMPMTCLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYS_ROSCS
Sequence: MLDIRLIREQPDMVKAALGRAGVDPAQVDAVLAYDEQRRALLREVEKLKALRNAVSKEIGKMSDAGERDTKIAEMRAVGDRIAALDRELAAVEERQYAALMELRNLPHPAVPDGPDETYNVVIAQEGEPRAFDFAPKPHWELGEALDIIDFERGVKLSGSRFYVLKGLGARLQRALIQWMLDLHIQQGYHEVYTPFVVKEQCMWGARQLPKFRDNLYRDVEDDLWLVPTAEVPVTNLHRDEILEADQLPLRYCAYTPCFRREKMSAGRDVRGIKRGHQFDKVEMYMFVHPDTSYDELEKLRADAEATCRLLGLTFRTKELCTGDLGFAATRTYDIEVWAPGQGEWLEVSSCSNVEAFQARAANIRYRSAPGARPEYVHTLNGSGLGLPRTLIAIMENYQQADGSIIIPDVLRPYMGGAEVIRRS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_HAEIN
Sequence: MDLYAVWGNPIAQSKSPLIQNKLAAQTHQTMEYIAKLGDLDAFEQQLLAFFEEGAKGCNITSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLQRLNWLRPNQHVLILGAGGATKGVLLPLLQAQQNIVLANRTFSKTKELAERFQPYGNIQAVSMDSIPLQTYDLVINATSAGLSGGTASVDAEILKLGSAFYDMQYAKGTDTPFIALCKSLGLTNVSDGFGMLVAQAAHSFHLWRGVMPDFVSVYEQLKKAML
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NMDE4_HUMAN
Sequence: MRGAGGPRGPRGPAKMLLLLALACASPFPEEAPGPGGAGGPGGGLGGARPLNVALVFSGPAYAAEAARLGPAVAAAVRSPGLDVRPVALVLNGSDPRSLVLQLCDLLSGLRVHGVVFEDDSRAPAVAPILDFLSAQTSLPIVAVHGGAALVLTPKEKGSTFLQLGSSTEQQLQVIFEVLEEYDWTSFVAVTTRAPGHRAFLSYIEVLTDGSLVGWEHRGALTLDPGAGEAVLSAQLRSVSAQIRLLFCAREEAEPVFRAAEEAGLTGSGYVWFMVGPQLAGGGGSGAPGEPPLLPGGAPLPAGLFAVRSAGWRDDLARRVAAGVAVVARGAQALLRDYGFLPELGHDCRAQNRTHRGESLHRYFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGPTHRMDFLLAFSRGMYSCCSAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPESQPLLGPGAGGAGGTGGAGGGAPAAPPPCRAAPPPCPYLDLEPSPSDSEDSESLGGASLGGLEPWWFADFPYPYAERLGPPPGRYWSVDKLGGWRAGSWDYLPPRSGPAAWHCRHCASLELLPPPRHLSCSHDGLDGGWWAPPPPPWAAGPLPRRRARCGCPRSHPHRPRASHRTPAAAAPHHHRHRRAAGGWDLPPPAPTSRSLEDLSSCPRAAPARRLTGPSRHARRCPHAAHWGPPLPTASHRRHRGGDLGTRRGSAHFSSLESEV
What is the function of this protein?
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851).  Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 2D, GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, NMDAR2D, NR2D.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: YPF10_PLAF7
Sequence: MKKDEKNNMDESLEEYDEENYTSELDDLPEYERELILAKRHEEYMKKKHRRMLLKNLHIDEKSKGNIHDDTNKSIETSNKRKGKLNNKKLKLKKKLYESDEEEENDKNDKNDDDQYDNTYQSDEDRKKSNNKKKEQSKKIKGDNESYNIDSISYVKYKKGKIKILEDDDEKNHEDEKKKTDIIDHVSVTDDSYTDSSYKNKKKSKYKKGDTNQTDKTSKKNKNDKTNKTNKTNVSIKTKKHREDYSDDSMDDYHSTSSYEHEKSSDVHYNKKEKKIQLKVISEESHLDNTKNKTGKGLNKILIEKEKKKKKKDLHIVDSVHKNKEDGKNVITDIFEKNEKINKDKELELPQTPERLIHLYKEEKKIKMDIYNYMTYDIITYFQLKKTFLLDMCEHVHFSYHVIGHMIKIIDISKLNKVTNQDVQNTNNKKKIDTANENKKKIFFITNVIKSEPYFSTDRNTNIKFEVAHLENLAHSKFFKKIKNIMYQNKKISMDEIKSNEYYETYICDMNNISDQKFTIDEYNHIKLFSIDLDVLKTFHLFLKEKNEDLKNFRYTEKQLQDLFEKKKQKSFYEIYTNNKSIDNLPITRITVQREICSIQREIDKLNFDKKKTNVNDTYTLSKLNNQINELTKKINILRGNLDKARKNHAAMKSNDQFAQEKNMTKEKSRTNIKSTQKDDATNKFLGVKEMDISYFSKQIYDEKTNFNNMLSSKFINLPLDVHHKVVHHFLLGTIQNNDAVFYDDPSHKIKKELDAEIDKLLGLHGNRHITLFDDIKKNYE
What are the official names of this protein?
Uncharacterized protein PF3D7_1225600.
Protein: SRD46_CAEEL
Sequence: MLHIFLSYFYIIFFLIVFPTQLLLLYVIIFHSPKHLKTLKRIFLCNCSCQIFSMITLVLLQARQVSNLNPVELWCYGPLRYLDAIVAYTMYVLCEGTVLMSSILIFITMYVKYEAVRSIHRERSAKFSVIILSLSPLFITMSAEAYLTIEYHLPIEYQEKFSAINSNLGDHTVIGYIALDNIPAQIVFCTICGFFVIFPLIMFCLRRNIILFINSKLDLSSTTMRQQNRALINGLTLQAFLPLFCVCPIFICSFVALITKTEILLEQYFVSVVLLLPTFFEPYITFYTVSHYRKQVRIWLGKENMGSMMLVVSVSRL
What are the official names of this protein?
Serpentine receptor class delta-46, Protein srd-46.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.