PharMolix/UniProtQA huggingface dataset:
Protein: NSP11_WTV
Sequence: MSNKESNVALQTLRVTKDMKDFLSHRIVGEPPANIKIEYQKIHRYRTCVCPSTGHISELCPSGDLILSLGAHRNVIAAATVYDVVKNKIKSTTSKAGTSSTLSSLGLSGFQKPKIGSKNKKTMFSKQNNSTNESDESGGEEGSSLNDLPKSDLINAIMELASQGRNNSKGKGKRGGKR
What is the function of this protein?
Constituent of viral factories.  Binds to ssRNA and dsRNA (By similarity).
What are the official names of this protein?
RNA-binding protein, Non-structural protein 12, Pns12.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus RNA-binding protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PUP_MYCTO
Sequence: MAQEQTKRGGGGGDDDDIAGSTAAGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.  Among the identified substrates are the FabD, PanB and Mpa proteins (By similarity).
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: RNH2_HAEDU
Sequence: MRTNFIYHNANLIAGVDEVGRGPLVGAVVTAAVILDPQQPILGLADSKKLSEKKRILLATEIKQKALCWSLGRAEAEEIDQLNILHATMLAMQRAINALTIQPDFVLVDGNRIPSLNMPAQAIVKGDSLVAEISAASILAKVARDHEMQILDQQFPEYGFAQHKGYPTKLHIEKLAQFGATPFHRKSFAPVRKILGL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SYMTH
Sequence: MNESLKRTPLYELHLKLGARMVPFGGWEMPVQYSSVIEEHRAVREAAGLFDVSHMGEFEVRGPQALDLIQLVSTNDAAKLAVGRVQYALMCYENGTVVDDILIYRLDEHRYWLVVNAGNTQKDWEWINTARERAGLHNLELIDRSAEIALLALQGPKAEEILQPLATGVVLSQLEPFSLAKNVTVSGVPTLVLSRTGYTGEDGFEIYVKAEDVAALWEALLEAGDEQGLLPCGLGARDTLRFEAKLPLYGHEISDQHNPLEAGLGFAVKLKKGVDFIGRDALARIKEQGPTRKLVGIEMIDRGVPRQGYPVAVGGEVVGEVTTGSFSPTLEKNIALAYVPVAHSAVGTEVEVIIRGRALKARVVETPFYRSPHRR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: X_HBVB8
Sequence: MAARLCCQLDTARDVLCLRPVGAESRGRPLPGPLGALPPASPSAVPTDHGAHLSLRGLPVCAFSSTGPCALRFTSARRMETTVNAHRNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFTEWEELGEEMRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: T22D3_PONAB
Sequence: MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAPGGSAV
What is the function of this protein?
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11.  In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10.  In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation.  In vitro, suppresses AP1 and NFKB1 DNA-binding activities.  Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).
What are the official names of this protein?
TSC22 domain family protein 3.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, localizes to the cytoplasm, but in differentiating myoblasts is localized to the nucleus (By similarity).
Protein: SSN8_GIBMO
Sequence: MSANYWHSTQCRFWSFTKEQLVTMRQKLEEDNAELVRMFPLPQQRRLYIYFNQQLIRLAKRLTIRQQSMATAQVYMKRFYSKVEIRRTNPYLVIATAIYLACKIEESPQHIRLIVTEARQMWGDLVAIDTSKLGECEFFMISEMRSQLIVFQPYRTITALRNELSLVDDEVQLARSVINDHFMTDLPLLYPPHIIAMVAILLALVLRPNNSGPGQSTSGAAAAAGLAAAQQALMRAQGQQAQGGMPEPAAAEPKEKRQQDRVSRVQKFAKWLVDSNVEIASMVDATQEIISFYECYEHYNDKLTREQINRFVKARGLDK
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).  May play a role in signal transduction pathways regulating secondary metabolism and fungal development (conidiation).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_YERPN
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFQKFIEQDPEGQHGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITARHIRQLEKDGIDRIEVPVEYIAGKVVAKDYVDASTGELICAANMELSLDLLAKLSQAGHKQIETLFTNDLDHGAYISETLRVDPTSDRLSALVEIYRMMRPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKEDITEVMKKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVRDGVVTDEINYLSAIEEGNFVIAQANSNLDDEGRFLEDLVTCRSKGESSLFSREQVDYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTSVAKRGGTVQYVDASRIVIKVNEDEMHPGEAGIDIYNLTKYTRSNQNTCINQMPCVNLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLTEELQILEAGLFARIHAVLVSGGIEAEKLSKLPRERWLELGLTDEDKQNQLEQLAEQYDEMKSEFEKKMDAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKKQEEVAKLREFIQKAYDLGDNVCQKVDLSTFTDDEVLRLAENLKKGMPIATPVFDGATEKEIKELLQLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: STE24_YEAST
Sequence: MFDLKTILDHPNIPWKLIISGFSIAQFSFESYLTYRQYQKLSETKLPPVLEDEIDDETFHKSRNYSRAKAKFSIFGDVYNLAQKLVFIKYDLFPKIWHMAVSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDLPLSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFLWYIMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNSTDEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIGFMLFNDLLTPLECAMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYSSYHYSHPTLAERLTALDYVSEKKKN
What is the function of this protein?
Proteolytically removes the C-terminal three residues of farnesylated A-factor mating pheromone.  Also acts to cleave the N-terminal extension of the pheromone.  Does not act on Ras.
What are the official names of this protein?
CAAX prenyl protease 1, A-factor-converting enzyme, Prenyl protein-specific endoprotease 1, PPSEP 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48A family.
Protein: ARGB_SACD2
Sequence: MQTQDQALEVAKVLTEALPYIQRFTGKTIVVKFGGNAMTDTELQNSFARDIVLMKLVGMNPIVVHGGGPQIGDLLKKLNIESSFVDGMRVTDSATMDVVEMVLGGTVNKQIVSLINRNGGQAIGVTGKDGNLIHAKKLTVNRKSPEVQASEIIDIGHVGEVKTINRSVIDVLVNSDFIPVIAPIGVGDDGASYNINADLVAGKVAEVLQAEKLMLLTNVAGLQDKSGQVLTGLTTGRVDELIADGTIYGGMLPKISCALDAVKCGVKSAHIIDGRVPHAVLLEIFTDSGVGTLITNEYSA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_LEPBJ
Sequence: MSLKSLLKGFKRPKKIEFNTEASTPNYGKFVAEPFERGFATTIGNSLRRTLMSSIEGAAISAIRIEGVNHEFSFIEGVAEDVTRIILNLKQVRIKYEPEEKDQSKIIHLELKGAGYFRAGDLAVDSSIEIMNPDLHIATLNEDANLVMDLEIQRGRGYVPAEEKKKDIEVLGTIPVDSIFSPVQKVVFEVSETRVAQRSDYEKLTLEVWTDGSVSPDDAVAQAAKILKEHLTVFINFEEELEEEDDELDEADEKLKASLSKHVEELELSVRSLNVLRSLEIDFIGDLVKRSEEEMSKSKHYSDQCLQELKGKLSTLGLSFGMRDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PROQ_KLEP3
Sequence: MENQPKLNSSKEVIAFLAERFPQCFSAEGEARPLKIGIFQDLVERVGGEMNLSKTQLRAALRLYTSSWRYLYGVKAGAIRVDLDGNPCGELEEQHIAHARQQLEEAKARVQTQRAAQQAKKREAAAAAGQQDEGVRRERKPRPQQPRRKEGAEQRKPRPVAAKAPREERHTPVSDVSVLTVGQALKVKAGNNAMDATVLEITKDGVRVQLTSGMSMIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAXB1_RAT
Sequence: MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEQYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLVSVLEKETAQLREQVGRMERELSHEKSRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATSKAHQLEEDIVSVTHKAVEKETELDSLKDKLRKAQQEKEQLECQLKTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNVDGNKESMITHFKEEIGKLQSCLADKENLHRALLLTTSNKEDTLLLKEQLRKAEEQVQATRQELIFLAKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKTDQEKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSASSNGVFTKRMGSQQKVNDASINTDPAASASAVDVKPAASCAAETDFDMSAKDHVCEVTKEMAEKVEKYNKCKQLLQDEKAKCNKYADELAQMELKWKEQVRIAENVKLELAELEDSYSLQLAEKDKEINCLASFLENLSREKELTKSLEDQKGRKMEGQSPQQVSRCLNTCSEQSGLLPTLPAAQPVLQYGNPYTAHETRDGADGAFYPDEIQRPPVRGPSWEDNVVCSQPARNLSRPDGLEDPEDSREDENVPIPPDPANQHLRGHGAGFCFDSSFDVHKKCPLCELMFPPNYDQIKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD
What is the function of this protein?
Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation.  Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates.  Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production.  Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways.  Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling.  As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis.  Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation.
What are the official names of this protein?
Tax1-binding protein 1 homolog, Liver regeneration-related protein LRRG004.
Protein: NEF_SIVVG
Sequence: MGLGNSKPQHKKQLSLWHALHKTRATRYGLLADPLIGQSSTLQEECDKALKESLIRKRNGKMTPEGRKLQEGDKWDEWSDEEDEVGFPVRPRVPLRQMTYKLAVDFSHFLKEKGGLDGIYYSDRRNQILNLYALNEWGIIDDWNAWSEGPGIRYPRCFGFCFKLVPVDLHEEAETCERHCLVHPAQVREDPDGINHGEVLVWKFDPMLAVQYDPNRKYLTDMHDLGKRK
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: RK20_EUGGR
Sequence: MTRIKNNGISKKKRKRKISKMKGWVGGHSKLFRTGNQQLMKARHYAFYDRKKKKNLNKTLWITRINGGLKYYLTINEKYNIFVSFLRKTKTYVNKKLLSEINVRDSKSFSHLSKPIMKSTGINL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NOS2_CARAU
Sequence: FGFHQQMLNYILSPFFYYQPDPWLTHKWKDEKRNMRKHSISFKGLIRAVLFSQTLIKSALAKRVRCTVLYATETGKSKTLAKKLNTMMNYAFSSKVVCMEDYNFSELEKESLLFVVTSTFGNGDCPGNGESFKKQLLSLNNLRNQVRYSVFGLGSRMYPHFCAF
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2 (By similarity).
What are the official names of this protein?
Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: NETR_HUMAN
Sequence: MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYPYYLPTQQRPPRTRPPPPLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL
What is the function of this protein?
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
What are the official names of this protein?
Neurotrypsin, Leydin, Motopsin, Serine protease 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEPA_RHOOB
Sequence: MTVARNRAGAGPGKGSPISSFADKTFTDPARIRNFCIIAHIDHGKSTLADRMLQLTGVVEERQMRAQYLDRMDIERERGITIKAQNVRLPWKVGDDEFVIHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLAMEKDLTIIPVLNKIDLPAADPDRYAEEIAHITGCEPGDVLRVSGKTGMGVKELLDEVVRQVPAPVGDPDGPARAMIFDSVYDAYRGVVTYVRVVDGRISPREKITMMSTGATHDLIEVGIISPEPKASIGLGVGEVGYLITGVKDVRQSRVGDTVTAARGGATEPLVGYRDPKPMVYSGLYPLDGSDYPVLRDALDKLRLNDAALAYEPETSVALGFGFRCGFLGLLHMEITRDRLEREFGLELISTSPNVVYRVVMEDGAEHVVTNPSYWPEGKIREVYEPMVKCTVIAPSEFIGAIMELCQNRRGELGGMDYLSETRVELRYEMPMGEIMFDFFDALKSRTKGYASLDYEEAGEQQADLVKVDILLQGEAVDAFSSIVHRSAAGAYGGRMTSKLRELIPRQQFEVPIQAAIGSKIISRENIRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSSESVGDKPKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNC_UREPA
Sequence: MDNKKFLDFLKQNRIEPKNLSIYLEALTHKSYANEHKLTKNYQRLEFLGDACVEWVISNFIFNYKIKDNEKMRSLDEGEMTRARSNMVRSEILSYAAKDLGLTDFLMIGVGLEQDQSARMEKIYEDIFEAFIGAVAQDQGIKKVSLILEKTLIKYFREGQINYQKDYKTIFQEQAQRINKKPIMYKLVRNEGDKKEVHLVWNDLIYGIGIASTRKEAEILAAKNAILKLDDYTKKA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_SHIF8
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTFMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFVWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL1_NOSS1
Sequence: MTKKVSRRLRELQAKVEDREYGPLDALGLLKETATAKFGEAAEAHIRLGIDPKYTDQQLRTTVALPKGTGQIVRVAVIARGEKVTEASNAGADVVGSEELIDEIQKGRMDFDKLIATPDVMPQVAKLGKMLGPRGLMPSPKGGTVTFDVASAIAEFKAGKLEFRADRTGIVHVMFGKASFSPEDLLVNLKALQETIDRNRPSGAKGRYWRTFYVSATMGPSIRVDINALRDYKLTEAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRPB_HALVD
Sequence: MSADGKFGDYGGQYVPEALMPAIEELTDAYERYVLDNEDGFMDDFRARLRDFGGRPTPLQRADRLSERYDREVYLKREDLLHGGAHKLNNALGQVLLAKYMGKERIIAETGAGQHGTATAMACAHLDMPCEIYMGERDINRQRPNVFRMKLNGSEVNPVTVGRGTLKEAISETMRDWATNVEDTHYVIGSVVGPHPFPSMVRDFQSVISEEARTQAREKLGRLPDAVVACAGGGSNTMGAFAEFVDDEETALYAVEAGGSTLEVDEEAGVAPNSASLTTGSEGILHGARTRLLQDRDGQIMESHSVSSGLDYAGVGPELAHLVDTGRVTAVNVDDDAALTAFHRLSQMEGIIPALESAHAFGYLESVVGPDAPDAENADDLGEYVVVNVSGRGDKDLESAIEETYERDIDIAPNMDEFTGGL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: KDPA1_STAAM
Sequence: MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHILNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit 1, ATP phosphohydrolase [potassium-transporting] A chain 1, Potassium-binding and translocating subunit A 1, Potassium-translocating ATPase A chain 1.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.