PharMolix/UniProtQA huggingface dataset:
Protein: AST1_YEAST
Sequence: MAKDILKNQDPKLQAMIVEHSAPAPKEIPMDAPVLKRVARPLRHVKFIPIKSLIFHTKTGPMDFSYEKKIKTPIPKNKIVVRVSNVGLNPVDMKIRNGYTSSIYGEIGLGREYSGVITEVGENLNYAWHVGDEVYGIYYHPHLAVGCLQSSILVDPKVDPILLRPESVSAEEAAGSLFCLATGYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQLLKRHYKLQKKLVIVTSANGPQVLQEKFPDLADEMIFIDYLTCRGKSSKPLRKMLEEKKISQYDPVEDKETILNYNEGKFDVVLDFVGGYDILSHSSSLIHGGGAYVTTVGDYVANYKEDIFDSWDNPSANARKMFGSIIWSYNYTHYYFDPNAKTASANNDWIEQCGDFLKNGTVKCVVDKVYDWKDHKEAFSYMATQRAQGKLIMNVEKF
What is the function of this protein?
Lipid raft-associated protein involved in the targeting of PMA1 from Golgi to the plasma membrane (PubMed:7822420, PubMed:11739806).  May induce clustering of PMA1, which facilitates partition of PMA1 into lipid rafts after leaving the ER and its transport to the cell surface (PubMed:11739806).
What are the official names of this protein?
Protein AST1, ATPAse stabilizing protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane raft; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein.
Protein: ISPH_THESQ
Sequence: MKIVVAKNIGFCFGVERAIRTVEELLDEGKKVVTDGEIVHNKQVMEQLTKKGLKVSSEMTDGEVFVVRAHGIPKDRLEELKKIFPEVVDLTCPIVSQLFKTAQRYAKERKVIVFGKEDHPEMVALRGYAPAIVTKVPFKFEEKKVVFLSQTTSSLEEYKEFVAAMIRMNEFEEAVFLNTICPVTVNREREVEELSKICDLSIVVGGKHSSNTGKLFRIASKHSKTIWIESPDELPADVVKYGTVCVFSGTSTPNSLIENVVRKLKEMEGKRDGTI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RBL_CRARM
Sequence: VGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTU_ACIBT
Sequence: MAKAKFERNKPHVNVGTIGHVDHGKTTLTAAIATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPGDDTPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLLDEGRAGENCGILLRGTKREEVQRGQVLAKPGTIKPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPGLRFAIREGGRTVGAGVVAKVTA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ACIF5
Sequence: MQNLYIKTYGCQMNEYDSERMADTLAVSHGLRLVDDPVLADVLLLNTCSIREKAEDKVFTQLGFWRPFKERRPEVVIGVGGCVASQEGERLRRRAPYVDLVFGPQTLHRLPDLLDACLAERRPQVDIAFPMLEKFDHLPQRPGRDGATAFVTIQEGCDKFCTFCVVPHTRGREYSRSMPDILREVRALVEQGVREITLLGQNVNAYRGATGLVGEGGLADLLERLARIPGLLRLRYTTSHPANLDDELIAAHGSIGILAPHLHLPVQSGSDRILRRMHRKHTVGQYLDKVDRLRAARPGIQISSDFIVGFPGETDADFAATMELIDAVRFDQSFSFKYSQRPNTPALKLKDSVPEAVKEDRLAVLQGRINGLAQGYAQALVGTQQAVLITGPSRRDAQELTGKTACNRAVNLAGSMDWVGQMLDVEITAALPNSLRGRAALVAPTSQRLAV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFB_SALTI
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDKPQVVVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_BACC7
Sequence: MITKADKNATRKKRHARVRAKLTGTAERPRLNVFRSNQHIYAQVIDDVNGVTLVSASTLDKDLALNGTSNIEAATKVGESVAKRAVEKGVKEVVFDRGGYLYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PROA_MYCMM
Sequence: MTLQAAPRSAAAQQREPDLRQEVHDAARRARVAARLLAVVPTGVKDRALHAAADAILAHVDRILSANAEDLDAARAADTPAAMLDRLALNPQRVDGIAAGLRQVAGLPDPVGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLTLKSGNAALLRGSSSAARSNEALVNVLRSALDSEQLPADAVQLLSSADRSTVTHLIQARGLVDVAIPRGGAGLIDAVVRDAQVPTIETGVGNCHVYVHEAADLDVAERILLNSKTRRPSVCNAAETLLVDAAIAEHAMPRLIGALQDAGVTVHLDADEQDLRREYLAMEIAVAVVDGVDGAIAHINEYGTGHTEAIVTTNLAAAQRFTERIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIVWGEGHTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_BORBR
Sequence: MSRFTYAYMMMTRLETLKNNLQAAFGQDLALTESLGELTLEVAAEQWFSACTKLRTDPALRFESCIDLCGVDYLTWGNGTQPEEKTGPVTRGRYAVVVHLLSIEHNWRLRVRTWAPDDEFPMVSSLLECWPGVNWFEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPLSGTVEMRYDPEQKRVIYQPVTIDPREITPRVVREDSYGMGR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK14_CUSOB
Sequence: MIQSQTHLNVADNSGARTIMCIRIIGSSNRRYAHIGDIIVAVIKDAVPNMTLEKSEVVRAVIVRTRKELKRDNGIILRYDDNAAVIIDKEGNPKGTRIFGAIPRELRKLNFNKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RL24_MYCPU
Sequence: MKTKLRKNDEVIVIAGSYKGTKGTILKVLPKQQRVQVKGVNVVTKHVKPSQSNSEGSIQNFEAPIHISNVAYVHKSGPKDKSGIASKISYEKRKDKKVRIARKTGKVI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: METXA_DEIGD
Sequence: MTALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAILVLHALTGTSAVHEWWPDFLGEGKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPLTLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLECPDLVDRAVIIGAPARHSPWAIGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEHQGEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGLLPRGQYLELQSPHGHDAFLIDPQGLPEAAAAFLHGA
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_ACIAC
Sequence: MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPNGGDGGRGGHVFAVADPSLNTLVDYRYSRRHEAKRGEHGMGSDMFGAAGDDITLKMPVGTIISDADTGEVLFELLKPGETITIAKGGDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLADVGLLGMPNAGKSTFIAAVSNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRLLLHVVDLAPFDESVDPVAQATAIVGELRKYDAELYEKPRWLVLNKLDMVPGDERAARVKDFVKRFRWKGPVFEISALTREGCEPLIQAIYQHVRAQQQAEQVQEVVDPRFADDAASD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_YERPS
Sequence: MANRTIIAFDFGTKSIGVAIGQEVTGTARALTAFKAQDGTPDWQQVEKLLKEWQPNLVVVGLPLNMDGTEQPLTARARRFANRLHGRFGVQIALQDERLSTVEARANLFDRGGYRALDKGSVDAASAVIILESWFDEQAG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIR_PSEAE
Sequence: MSANSLLGSLRELQVLVLNPPGEVSDALVLQLIRIGCSVRQCWPPPESFDVPVDVVFTSIFQNRHHDEIAALLAAGTPRTTLVALVEYESPAVLSQIIELECHGVITQPLDAHRVLPVLVSARRISEEMAKLKQKTEQLQERIAGQARINQAKALLMQRHGWDEREAHQYLSREAMKRREPILKIAQELLGNEPSA
What is the function of this protein?
Positive controlling element of AmiE, the gene for aliphatic amidase.  Acts as a transcriptional antitermination factor.  It is thought to allow RNA polymerase read through a rho-independent transcription terminator between the AmiE promoter and gene.
What are the official names of this protein?
Aliphatic amidase regulator.
Protein: PSBA3_SYNJA
Sequence: MTTVIQRRSTSNVWEQFCEWVTSTDNRLYIGWFGVLMIPTLLTATTCFIIAFIGAPPVDIDGIREPVSGSLLYGNNIITGAVVPSSAAIGLHFYPIWEAASLDEWLYNGGPYQLIVLHFLIGVFCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGALFSAMHGSLVTSSLIRETSEEESQNLGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISIMAFNLNGFNFNQSIVDSNGRVVGTWADVLNRANLGMEVMHERNAHNFPLDLAAVEVAPAVRG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 3, PSII D1 protein 3, Photosystem II Q(B) protein 3.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FRHG_METBF
Sequence: MTNKIKIGHVHMSGCTGCLVSLADNNLGLIKILDDYADLVYCLTLADVRHIPEMDVALVEGSVCLQDHESVEDIKETRKKSKIVVALGSCACYGNITRFSRGGQHNQPQHESYLPIGDLIDVDVYIPGCPPSPELIRNVAVMAYLLLEGNEEQKELAGKYLKPLMDLAKRGTSGCFCDLMYDVINQGLCMGCGTCAASCPVHAITLEFGKPQGERDLCIKCGSCYGACPRSFFNLDVIPEFENINEIIANALKEGESDD
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit gamma, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma, FRH.
What is the protein family that this protein belongs to?
Belongs to the FrhG family.
Protein: Y1833_SYNR3
Sequence: MAGHSKWSQIKRTKAVVDAKRGAVFTRLGREISVAARAGADPDGNFQLRTAINKAKAAGVPAANIERAIAKGCGAGGDGSQAFEEIRYEGYGPGGVAVLVEVLSDNRNRTAAELRLAFSKNGGNLGESGCVGFLFSHRSEVSLNATSAEGIDEDALLEDLLELEADGYELTEEGALVHGPFTALEILQDGLRQRGWSVQDWGHQWHPLNSIDLHQSDQARQCLQLLEALEALDDVRSVSCNLGEFPELENERS
What are the official names of this protein?
Probable transcriptional regulatory protein SynRCC307_1833.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_PROMA
Sequence: MKPLKILISNDDGVFAEGIRTLAIAAASRGHEVTVVCPDQERSATGHGLTLQAPIRAERADELFNEGIQAWGCSGTPADCVKLALNELLKEKPDLILSGINHGPNLGTDIFCSGTVAAALEGTLEGIPSLAVSIASFQWRKFKLAGELALNIAENAINQKWPKKLLLNLNIPPCDSEQMGKPGWTRLSIRQYQEQFSKRKDPRGNAYYWLAGEAVKDLESAGDGPKEWPSDVSQIETNSPSLTPIQPDLFWRGNVNDLPKLN
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIA10_MOUSE
Sequence: MKGYLVAIFLSSIFLYYVLYCILWGTNGYWFPAEEMRTRNNVNNCFKKPAFANLLRFPQLYPFLCRADFIKVAAMSGTNNFPLPYGIKTFETYFSSALSKLQSCDLFDEFDRVPCKRCVVVGNGGVLKNKTLGATIDSYDVIIRMNNGPVLGHEEEVGTRTTFRLFYPESVFSDSSHYDPNTTAVLVVFKPQDLRWLVEILLGKKINTQGFWKTPALKLIYKQYQIRILDPYITSEAAFQMLRFPRVFPKDQKPKHPTTGIIAITMAFHICSEVHLAGFKYNFYSPNSPLHYYGNATMSLMKQNAYHNLTAEQLFLNDIIKKKMVINLT
What is the function of this protein?
Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant.  Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids.  Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity).
What are the official names of this protein?
Type 2 lactosamine alpha-2,3-sialyltransferase, CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI, ST3Gal VI, ST3GalVI, Sialyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: SGRR_YERPN
Sequence: MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLPWLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQHCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA
What is the function of this protein?
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ.  Represses its own transcription under both stress and non-stress conditions.  Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
What are the official names of this protein?
HTH-type transcriptional regulator SgrR.
Protein: XRCC4_MOUSE
Sequence: MERKVSRIYLASEPNVPYFLQVSWERAIGSGFVITLTDGHSAWTATVSELEISQEADDMAMEKGKYIDELRKALVPGSGAAGTYKFLFSKESQHFSLEKELKDVSFRLGSFNLDKVSNSAEVIRELICYCLDTITEKQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALEADLYQRFILVLNEKKTKIRSLHKLLNEVQQLEESTKPERENPCSDKTPEEHGLYDGSTDEESGAPVQAAETLHKDDSIFSSPDVTDIAPSRKRRHRMQKNLGTEPKMAPQELPLQEKERLASSLPQTLKEESTSAENMSLETLRNSSPEDLFD
What is the function of this protein?
Acts as an activator of the phospholipid scramblase activity of XKR4 (PubMed:33725486).  This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell surface (PubMed:33725486).
What are the official names of this protein?
DNA repair protein XRCC4, X-ray repair cross-complementing protein 4.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XRCC4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to site of double-strand breaks. SUBCELLULAR LOCATION: [Protein XRCC4, C-terminus]: Cytoplasm. Note=Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3).
Protein: TRPG_CYACA
Sequence: MILIIDNYDSFSYNLVQSVGEINSDLIVLRSDEIDVSKLQNLNIKHIIISPGPGHPDEYTICKQVVKFFAPYTPILGICLGHQIIATCYNASIKKSSPVFHGRASKIYCLKDKLFLGIHAPFTAARYHSLVVDQDKRGLDLTTCLKTIAITREGVIMACKHRYYHFTYGIQFHPESMLTIQGTKLLKNFLSLSYG
What are the official names of this protein?
Anthranilate synthase component 2, AS, Anthranilate synthase, glutamine amidotransferase component.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GEP3_CANAL
Sequence: MFSRSILLRSVRKSLGRYYSSQAHPQTYIYNLLSDTKCRSCGIQLQDKFPDKPGYYRLPGQNDSNTDKKAKTSELNKKYEKILQNLDISDRNLLINNFSAPKQDDEKVASVPSLQQITPVEADTRDTTKDQQTHSGHSLSCKRCNDVIYNSKTRSIYDPNRDNLNKSEFPIPKLQQVLSTIPVDAPLVYVFSANDFPMGINKDIFQYRPPQQIYFVMTKSDILIPKTNVAFYNNFKKFLQNYMFKKFNVPRENVFIASGKDRWKMTDLYHFIPNYSYIIGDTNCGKSTLVKSLLINHHVKHWKYEALQQRPDEKQSSSASLKNKDFKKLDRLIDSFSSKNGPGTSHIPGFTRDVVPVDIDGIKELFDVPGFTTNENLQDIFDKLNHKQIARITKGANTSKYGSLKSKFDTVKNGQVLSLNGVGYLQFPGQDSMYQIRNVTKFALHKFKNLEKVDSILQRNEIPKSMSSHFIVNRQQQQQQRNELRGYYKRYIIPPFYGTIDLVIKDIGYINIKPTGKKLTNELMVLYLHPSLEAIIRQPILNYIDSPTPKKSPDGTNRKTITSDISKTPFYSRLIPSTVLSDPSSLVLSPPSSDYNQLNQYLQIDESSESAYNDLLELDETNKYDYWIE
What is the function of this protein?
May be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROP_ECO57
Sequence: MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAAFNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGATPAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE
What is the function of this protein?
Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine.  It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response (By similarity).
What are the official names of this protein?
Proline/betaine transporter, Proline porter II, PPII.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBCL_ECOLI
Sequence: MKTLIVSTVLAFITFSAQAAAFQVTSNEIKTGEQLTTSHVFSGFGCEGGNTSPSLTWSGVPEGTKSFAVTVYDPDAPTGSGWWHWTVVNIPATVTYLPVDAGRRDGTKLPTGAVQGRNDFGYAGFGGACPPKGDKPHHYQFKVWALKTEKIPVDSNSSGALVGYMLNANKIATAEITPVYEIK
What are the official names of this protein?
UPF0098 protein YbcL.
What is the protein family that this protein belongs to?
Belongs to the UPF0098 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MATK_PHRAU
Sequence: MEKFEGYSEKQKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIIGCNNKKFSSLLVKRLIIRMYQQNFWINSVNHPNQDRLLDHSNYFYSEFYSQILSEGFAIVVEIPFSLGELSCPEEKEIPKFQNLQSIHSIFPFLEDKFLHLHYLSHLEIPYPIHLEILVQLLEYRIQDVPSLHLLRFFLNYYSNWNSLITSMKSIFLLKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIHFSRKMEHFGVMYPGFFRKTIWFFMDPLMHYARYQGKAILASKGTLLLKKKWKSYLVNFSQYFFSFWTQPQRIRINQLTNSCFDFLGYLSSVPINTLLVRNQMLENSFLIDTRMKKFDTTVPATPLIGSLSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRISRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFSLMFTKTTHFSFHGSHSERIWYLDIIRINDLVNPLTLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1535_CLOBK
Sequence: MPNKFLIIDNSILPDIFEKVVKVKELLANGKVKDITEGVKTVGISRSTYYKYKDFVFSVSEGVKSQKATIGLLLGHERGTLSKILDRIAEYQGNILTINQDIPINNTANVSITFDISQMSIGLKELVEEIKNTKNVIKVDLIAME
What are the official names of this protein?
UPF0735 ACT domain-containing protein CLD_1535.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: SWM2_LACTC
Sequence: MNAAPRDLLRQFLDSFTDIAVIPVRLTPVLSRYYDAIAKDPELSKLALEKCNYVLENLSAHSPEIVTRCSRLYEALTAAKERDAAGNLIVEHINLESVSDMPFLSRDQHMANLIIEEIDVADYIEESPS
What are the official names of this protein?
Nucleolar protein SWM2.
What is the protein family that this protein belongs to?
Belongs to the SWM2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.