PharMolix/UniProtQA huggingface dataset:
Protein: EIF3A_CHAGB
Sequence: MPPPPHQKPENVLKRAHELIGVNQAPAALTLLHEHITSKRSRNVPIASLEPVMVLLVEQAVEQKKGKLAKDALYQYKNIAQNTNVGTIELVLKKFIELAAEKVTAAQQKADEVQSSIEATTGSSSVEDLEASETPESILLATVSGEQSKDRTDRAIVTPWLKFLWEAYRTVLDILRNNARLELLYQSTAMQAFDFCLKYARKTEFRRLCELLRNHVQTAAKYSAQMHAINLNDPDTLQRHLETRFQQLNVAVELELWQEAFRSVEDIHTLLSLSKRPAKNIMMANYYEKLTRIFLVGENYLFHAAAWSRYYNLLRQSAAMLATGQSKKSDSPPVSEADLQKAATFVVLSALSIPVISTSRSRGAMVDFDEARKNKNSRLTHLLGLSQAPTRSSLFRDVLSKALLRRASPQIRDLYNILEVDFHPLSICQKISPILAQVGADEEMQKYILPLQQVILTRLFQQLSQVYETVDLEFVQSLAQFPEPFQVTRGTIEKFIMNGNKKGDLAIRMDHATGVLSFDVDVFSSAKAVHAGSAAGSAENESGSVQRLQSTPSQIVRSQLTRLAEVLYTTCRYIDPSFNEARINARDAVLARAKAGAEKEHLEILSRKEVIQKRKDKASEIQAQKEKELARKKMLQEQALQQAEAQRLAEEQKIREQKRMAAEREEIKKKEVEGMLKDMKLDDVELEDLDNLDSNKIRMIKLQQLEREKNTIAEKLRVTGKRLDHLERAFRKEEAKKLPEDYAKQRERDIAAYELIKAQTLKEAELKHKEDVELKHRLTRLMPFYESFRADLHERRRDMFEKRRRDAERELEKQVTLRRKEYRERKLREKREREEKERALREAEERAEREKEEEKQRQEARKEELARLREEREKERERAKEAQARQQQREEEAMARRRAEKAAAAAVPIREREPFAATGSGPRLPLAGTKSTWREREAAKAAGGGAPSDSGPPPARAAPPPIERTDSRDRPAAGPPRLALAGNKPSWREREAAKNAAGGAPPPERSGPPPRVASGRGEPMDRAGSGRGGDRDARDNNGPAPEPLKASGGPGKYVPKFRREG
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCP_BUCAP
Sequence: MTTLKPGDIAPKFILPNCIDKSIKLSDFLGKKVLVYFYPKAMTPGCTVQACNIRDNLELFKSKKVEVLGISPDNTNKLLTFVEKKMLNFTLLSDKQNIVSKKFGVWGEKIFMGKKYFGIYRTSFLINSSGFIDKIFFKFKCKDHHKIILTYLNSKKSD
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Putative peroxiredoxin bcp, Bacterioferritin comigratory protein, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin Bcp.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
Protein: RS17_SHEPW
Sequence: MSDNIRTLQGRVLSNKMDKSITVAIERKVKHPLYGKFLKRTTKIHAHDEQNQCNAGDVVTIRECRPLSKTKSWTLVEVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: XERC_ECOSE
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SATP_ECO57
Sequence: MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIFYGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVYLGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLICGASAIYLAMGEVLNEQFGRTVLPIGESH
What is the function of this protein?
Uptake of acetate and succinate.  Transport is energetically dependent on the protonmotive force (By similarity).
What are the official names of this protein?
Succinate-acetate/proton symporter SatP, Succinate-acetate transporter protein.
What is the protein family that this protein belongs to?
Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URE2_ACTP7
Sequence: MIPGEYQLADGDVQANVGRKTVKLEVVNSGDRPIQVGSHYHFFETNHALKFDRLQARGMRLNVPSGNAVRFEPGEAKEVELVEFGGNKVIYGFHNEIDGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT1_CYPCA
Sequence: MDPCDCAKTGTCNCGATCKCTNCQCKTCKKSCCPCCPSGCSKCASGCVCKGNSCGSSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-1, MT-1, Metallothionein-I, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: PSBL_LACSA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YKFI_ECOLI
Sequence: MKTLPAITQRAVKPCLSPVAVWQMLLTRLLEQHYGLTINDTPFCNEAVIKEHIDAGITLADAVNFLVEKYELVRIDRKGFSWQEQSPYLRAADILRARQATGLLRQSRNNVVR
What is the function of this protein?
Toxic component of a type IV toxin-antitoxin (TA) system (PubMed:14594833, PubMed:28257056, PubMed:28931012).  Acts as a toxin inhibitor that blocks cell division and cell elongation via FtsZ and possibly also MreB (although no interaction with MreB has been proven) (PubMed:28931012).  Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation (PubMed:14594833, PubMed:28257056, PubMed:28931012).  These effects are overcome by concomitant expression of cognate antitoxin YafW, which leads to toxin loss by an unknown mechanism (PubMed:14594833, PubMed:28257056).  Overexpression leads to formation of lemon-shaped cells and cell lysis; inactivated by overexpression of cognate antitoxin YafW but not when the 2 genes are coexpressed from the same plasmid (PubMed:28257056).  Also neutralized by overexpression of non-cognate antitoxins YfjZ and CbeA (PubMed:28257056).  Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells (PubMed:28257056).
What are the official names of this protein?
Toxin YkfI.
What is the protein family that this protein belongs to?
Belongs to the CbtA/YkfI/YpjF toxin family.
Protein: LPXD_NITHX
Sequence: MTQPAFFKQPPPLTLVEIAASTGAQLIDASRGEQRITGLASLDQAGPMHLTFFDNHKYAAQLAATRAGACFVSPRFEASVPGHVAVLRSAAPFRAFVRIARDCHADTLRPQSWFDNATIAASAVVHPSAHLEDAVVVDPLAVIGPGVEIGTGSVIGSGAVIGPGVRIGRNCNVGAGTTIQVALIGNNVLIHPGCHIGQDGYGFIFFGSEGHVKVPQTGRVLIQNDVEIGAGTTIDRGSLRDTVIGEGTKIDNQVQIGHNVTIGRRCLLAAQIGLAGSLTIGDNVALGAKVGINNHLHIGDGAQVVAMSGVKDDIPPNGRWGGYFAKPTRQWYRELFAVERLARDGAPNAGSATPDPTDRGA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RUVA_NITEC
Sequence: MIGRITGLLLEKHPPLVLVDVQGTGYEIDVPMSTFCKLPDIGKKVTLHTHFWVREDVHLLFGFMTEQERALFRQLTKISGIGARTGLAILSGLSVTDLHQAVVSQDSIRLTKIPGIGKKTAERLLLELRDKIDPVAILSEAGAAASNVDKDILSALLALGYNGREVNRALEQLSEGVTVSDGIMQSLKFLSKVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CYB_LAMFL
Sequence: MSHPPTILRKTHPLLSLGNSMLVDLPSPANISAWWNFGSLLSLCLILQIITGLILAMHYTANTELAFSSVMHICRDVNNGWLMRNLHANGASMFFICIYAHIGRGIYYGSYLYKETWNVGVILFALTAATAFVGYVLPWGQMSFWGATVITNLISAVPYVGDDIVMWLWGGFSVSNATLTRFFTFHFILPFILAAMTMIHIMFLHQTGSSNPLGINSNLDKIQFHPYFSFKDIFGFVILLGVLFMISLLPPNALCEPDNFIYANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVMALAAAIMILLVIPFTHTSKQRGIQFRPLAQVTFWILIADLALLTWLGGEPAEHPFILMTQIASTVYFMIFILIFPILGRLENKLILLSKNTGKFNWNLTY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUOK_XANOM
Sequence: MITLGHLLGLGAVLFCISLAGIFLNRKNVIVLLMSIELMLLSVNVNFIAFSRELGDTAGQLFVFFILTVAAAEAAIGLAILVTLFRTRRTINVAEVDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1037_META3
Sequence: MDKRITLIGSKIAKTGNEFIYCGVLEECSECRFKKICHDGLIVGKRYRIVSVRSAKHPCIAYGDGVKVIEVEPSNNFTILIESKKALEGLTLSHSDIQCNNILCKYYNLCHSEGMPEKYKIMELHEKIKCPKGNSLIKATVSTIN
What are the official names of this protein?
UPF0179 protein Maeo_1037.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: TCOF_MOUSE
Sequence: MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGQKQKAEDDETLQAKKSRVSDPVSSSESSDQEKEEEAATERAKATPRPTPVNSATAALPSKVKEKGKTKTANKTVNSVSHPGSGKTVVHLLSGKSPKKSAEPLANTVLASETEEEGNAQALGPTAKSGTVSAGQGSSSSEDSSISSDETDVEVKSPAKPAQAKASAAPAKDPPARTAPGPTKLGNVAPTPAKPARAAAAAAAAAVAAAAAAAAEESESSEEDSDSEDEAPAGLPSQVKASGKGPHVRADSVSAKGISGKGPILATPGKTGPAATQAKAERPEKDSETSSEDDSDSEDEMPVTVNTPQARTSGKSPRARGTSAPAKESSQKGAPAVTPGKARPVAAQAGKPEAKSSEESESDSGETPAAATLTTSPAKVKPLGKSSQVRPVSTVTPGSSGKGANLPCPGKVGSAALRVQMVKKEDVSESSSAELDSDGPGSPAKAKASLALPQKVRPVATQVKTDRGKGHSGSSEESSDSEEEAAPAASAAQAKPALEKQMKASSRKGTPASATGASTSSHCKAGAVTSSASLSSPALAKGTQRSDVDSSSESESEGAAPSTPRVQGKSGGKGLQGKAALGQGVAPVHTQKTGPSVKAMAQEDSESLEEDSSSEEEDETPAQATPLGRLPQAKANPPPTKTPPASASGKAVAAPTKGKPPVPNSTVSARGQRSVPAAGKAGAPATQAQKGPVAGTGEDSESSSKEESDSEEETPAQIKPVGKTSQVRAASAPAKESPKKGAHPGTPGKTGSSATQAQPGKTEDSDSSSEESDSDTEMPSAQAIKSPPVSVNRNSSPAVPAPTPEGVQAVNTTKKASGTTAQSSSSESEDGDEDLIPATQPSTYALRTSVTTPAALSRAASQPSKSEQSSRMPKGKKAKAAASAQTSSAVETLPMMPPQSAPIQPKATNKLGKSKLPEKQQLAPGYPKAPRSSEDSSDTSSEDEEDAKRPQMPKSAHRLDPDPSQKETVVEETPTESSEDEMVAPSQSLLSGYMTPGLTVANSQASKATPRPDSNSLASSAPATKDNPDGKQKSKSQHAADTALPKTGRKEASSGSTPQKPKKLKKSTSSSPAPTQTLPNSITQRLLEQAWPLSEAQVQASVVKVLTELLEQERLKATEAIKESGKKSQKRKLSGDLEAGAPKNKKKKEQPVPRASAVSPEKAPMTSKAKSKLDKGSAGGKGKGSPGPQGAKEKPDGELLGIKLESGEQSDPKSKSKKKKSLKKKKDKEKKEKKKGKKSLAKDSASPIQKKKKKKKKSAEPAV
What is the function of this protein?
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification.  Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
What are the official names of this protein?
Treacle protein, Treacher Collins syndrome protein homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2149_LACPL
Sequence: MKMPKHNDNYQYPLDETWTTAEIIKVTTFYQAIEAANEGTIATADLLAAYRDFKTVVPAKSEEKRLARDYEAASGYRIYQTMRAAQETNKQRFQYRD
What are the official names of this protein?
UPF0223 protein lp_2149.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RL23_ARTS2
Sequence: MSAATIKDPRDVVLAPVVSEKSYGLIDEGKYTFLVDPRSNKTEIKLAVEKIFSVKVESINTINRAGKRKRTKFGWGTRKNTKRAIVTLKEGTIDIFGGPLA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TRXH1_BRANA
Sequence: MAATAEVIPAGEVIACHTVEDWNNKLKAAKESNKLIVIDFTAVWCPPCRFIAPIFVELAKKHLDVVFFKVDVDELATVAQEFDVQAMPTFVYMKGEEKLDKVVGAAKEEIEAKLLKHSQVAAA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes (By similarity).
What are the official names of this protein?
Thioredoxin H-type 1, Trx-H-1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERLN2_MOUSE
Sequence: MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTALKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGGLGKQFEGLSDDKLGFGLEDEPLEAPTKEN
What is the function of this protein?
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1.  Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex.  Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.  May promote ER retention of the SCAP-SREBF complex (By similarity).
What are the official names of this protein?
Erlin-2, Endoplasmic reticulum lipid raft-associated protein 2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2, SPFH domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Protein: CWP04_DAUCA
Sequence: GVREDTYPDVVXTA
What are the official names of this protein?
43 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PROT1_ARATH
Sequence: MTATEAKNRKINVGDGDDVVDIEIPDTAHQISSDSWFQVAFVLTTGINSAYVLGYSGTIMVPLGWIGGVVGLLIATAISLYANTLIAKLHEFGGRRHIRYRDLAGFIYGRKAYHLTWGLQYVNLFMINCGFIILAGSALKAVYVLFRDDHTMKLPHFIAIAGLICAIFAIGIPHLSALGVWLGVSTFLSLIYIVVAIVLSVRDGVKTPSRDYEIQGSSLSKLFTITGAAANLVFAFNTGMLPEIQATVRQPVVKNMMKALYFQFTAGVLPMYAVTFIGYWAYGSSTSTYLLNSVNGPLWVKALANVSAILQSVISLHIFASPTYEYMDTKYGIKGNPFAIKNLLFRIMARGGYIAVSTLISALLPFLGDFMSLTGAVSTFPLTFILANHMYYKAKNNKLNAMQKLWHWLNVVFFSLMSVAAAIAAVRLIAVDSKNFHVFADL
What is the function of this protein?
Proline transporter that mediates proline and glycine betaine transport.  May be involved in long-distance transport of proline and required for phloem loading, retrieval of proline leaking from the phloem, or in xylem-to-phloem transfer.  When expressed in a heterologous system (yeast), imports D- and L-proline, glycine betaine and GABA across the plasma membrane.  Has the same affinity for D- and L-proline.
What are the official names of this protein?
Proline transporter 1, AtPROT1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.3) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: GUAA_BRUA1
Sequence: MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALEGESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL14_DEIGD
Sequence: MIMPQTRLDVADNSGARELMCIRVLNSGIGGKGLTKGGGGNKRYAHVGDIIVASVKDAAPRGAVKAGDVVKAVVVRTSHAIKRADGSTIRFDKNAAVIINNQGEPRGTRVFGPVARELRDRRFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GDE_CANLF
Sequence: MGHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPFPGETFNREKFRSLEWENPTEREDDSDKYCKLNLQQAGSFQYYFLQGNEKSGGGYIVVDPILYVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLANQLELNPDFSRPNKKYTWSDVGQLVEKMKKEWNVLCITDVVYNHTAANSKWIQEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVAEGKYKEKGVPALIENDHQMNCIRKIIWEDIFPKIQLWEFFQVDVYKAVEQFRRLLTQENRKITTKPDPKEHLKIIQDPEYRRLGCTVDMNIALATFIPHDKGPAAIDECCNWFRKRIEELNSEKHQLVNYHQEQAVNCLLGNVFYERMAGHGPKLGPVTRKHPLVTRYFTFPFEEMTVSTEESMIHNPNKACFLMAHNGWVMGDDPLRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDITHDNECPIVHRSEYDALPSTTIVSMACCASGSTKGYDELVPHQISVVSEERFYTKWNPGASPSNTGEVNFQSGIIAARCAINKLHQELGAQGFIQVYVDQVDEDIVAVTRHSPSIHQSVVSVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYQKDKNSINGMPNITVEIREHIQLSESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPHFKSGSLAVENSDPILKIPFAFIASKLTLAELNQVLYRCEAEEQEDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCDNLRSGDWMIDYVSNRLISRSGTIAEVGKWFQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDIAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPSLPLLSPSLMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIALRGLLLITGRYLEARNIILAFAGTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSVPLSAGTLDQPLFEVIQEVMQRHIQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRLNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLSKSTVRWLLELSKKRIFPYHEVRVKRHGKVVTISYDEWNKKIQDNFEKLFHVSEDPXDFNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLWPVGYFLRAKLYFSKLMGPEANAKTVFLVKNILSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSIATVLETLYDL
What is the function of this protein?
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
What are the official names of this protein?
Glycogen debranching enzyme, Glycogen debrancher.
What is the protein family that this protein belongs to?
Belongs to the glycogen debranching enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Under glycogenolytic conditions localizes to the nucleus.
Protein: USBP1_HUMAN
Sequence: MSARATRPRSRRGRHAPPGELDPVAESSEEVEAASGSSKPSFAPPPVSSGLEQLGPMEEVSGQGLGSRTDKKMDGGSGRELASAPEVPHKPAVEAHQAPEAALQYKETVPPGNGAPDVFQTLQHTLSSLEAAAAAWRHQPPSHSGPMEFEGTSEGGAGSLGKQEGAGSCQREAARLAERNAWLRLALSSREDELVRTQASLEAIRAEKETLQKEVQELQDSLLRLEPCPHLSHNQAGGSGSGSSSSEADREPWETQDSFSLAHPLLRRLRSHSSTQILGSLPNQPLSPEMHIMEAQMEQLRGSIEKLKCFNRLLSAVLQGYKGRCEGLSMQLGQREAEATALHLALQYSEHCEEAYRVLLALREADSGAGDEAPMSDLQAAEKEAWRLLAQEEAAMDAGAQQNPQPSPEGSSVDKPTPQEVAFQLRSYVQRLQERRSLMKILSEPGPTLAPMPTVPRAEAMVQAILGTQAGPALPRLEKTQIQQDLVAAREALADLMLRLQLVRREKRGLELREAALRALGPAHVLLLEQLRWERAELQAGGANSSGGHSSGGGSSGDEEEWYQGLPAVPGGTSGIDGGQVGRAWDPEKLAQELAASLTRTLDLQEQLQSLRRELEQVAQKGRARRSQSAELNRDLCKAHSALVLAFRGAHRKQEEQRRKLEQQMALMEAQQAEEVAVLEATARALGKPRPPLPPPQLGDTFL
What are the official names of this protein?
Harmonin-binding protein USHBP1, AIE-75-binding protein, Mutated in colon cancer protein 2, MCC-2, Usher syndrome type-1C protein-binding protein 1, USH1C-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the MCC family.
Protein: STHA_MYCBT
Sequence: MREYDIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTLREAVLYLTGMNQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLAVTFRFGEEVTAVDVGSAGTVTTLASGKQIPAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDRFQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYVGATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATEMVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAALDVMNKMRALNQFRR
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.