PharMolix/UniProtQA huggingface dataset:
Protein: RHAM_SALTI
Sequence: MIRKAFVMQVNADAHEEYQRRHNPIWPELEAVLKSHGAHHYAIYLDQERNLLFATVEIESEERWNAVASTDVCQRWWKHMRDVMPANPDNSPVSAELKEVFYLQ
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTPN_CHICK
Sequence: MSDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHNITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKTLLQ
What is the function of this protein?
Regulates NF-kappa-B transcription factor activity.  Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation.  Promotes cardiac muscle hypertrophy.  Plays a role in the regulation of the growth of actin filaments.  Inhibits the activity of the F-actin-capping protein complex (By similarity).
What are the official names of this protein?
Myotrophin, Granule cell differentiation protein, Protein V-1.
What is the protein family that this protein belongs to?
Belongs to the myotrophin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Protein: RIC11_ARATH
Sequence: MAMKMKGIYKSFKSIMFVGKERDLEIGHPTEVKHVAHIGWGSSGSDPGWMSDFKAGAEFLSPRTSSFSHTRHSDSFFTTSDSTEFDQDQLNISDRIRDVPPIPVGLSKIHTKSKNRRKKPSSTSSPRSRPSPKSSRSMGLSKSSHKSMVSRLNSNA
What is the function of this protein?
Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family.  Participates in the propagation of ROP GTPase signals in specific cellular responses (By similarity).
What are the official names of this protein?
CRIB domain-containing protein RIC11, ROP-interactive CRIB motif-containing protein 11, Target of ROP protein RIC11.
Protein: RL17_CAUVC
Sequence: MRHGKAHRKLGRTSAHRTAMFANMSASLIKHEQIVTTLPKAKELRPIVEKLVTLAKRGDLHARRQAISSVRDVEQVGKLFAVLGPRYKERQGGYIRVLKAGFRYGDNAPMAVIEFVDRDVSEKGKDSGPVYVNDAED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYR_FRATF
Sequence: MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVISDVHLGDWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPITVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVALWQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDIKSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATC_MANSE
Sequence: MSEYWLISAPGDKTCQQTWEALNQATKANNLSLNYKFPIPDLKVGTLDQLVGLSDDLGKLDTFVEGVTRKVAQYLGEVLEDQRDKLHENLTANNDDLPHYLTRFQWDMAKYPIKQSLRNIADIISKQVGQIDADLKVKSSAYNALKGNLQNLEKKQTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKSMFNDWNANYEKITDMIVPRSTQLIHQDGDYGLFTVTLFKKVVDEFKLHARERKFVVREFAYNEADLVAGKNEITKLLTDKKKQFGPLVRWLKVNFSECFCAWIHVKALRVFVESVLRYGLPVNFQAALLVPSRRSARRLRDTLHALYAHLDHSAHHHANAQQDSVELAGLGFGQSEYYPYVFYKINIDMIEKAA
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit C, V-ATPase subunit C, Vacuolar proton pump subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
Protein: DPO4_VIBVY
Sequence: MSTQMRKIIHIDMDCFYAAVEMRDNPNFRSRPLAVGGHEKQRGVISTCNYEARKFGVRSAMPTAQALKLCPSLLVVPGRMQVYKEVSTHIRSIFSRYTHLIEPLSLDEAYLDVTDSTQCHGSATLIAEAIRRDIWNELQLTASAGVAPIKFLAKVASDMNKPNGQFVIPPEQVQSVIDTLPLQKIPGVGKVSLEKLNQAGLYVCQDVKNSDYRQLLKQFGRLGASLWQRSHGIDEREVIVERERKSVGVERTFTQNIVTYEQCWQVIEEKLFPELAIRLEKANPEKAIIKQGIKMKFADFQLTTIEHVHHELELAYFRELLQDILQRQKGREIRLLGLSVMLKPEEQARQLSLL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR12_BRUMA
Sequence: MWKLLANVVSNVVSQGWEVFVEVFVVSYRHIPSHTLSVPTDITVDKLNMLANKTLNNISDKEFESVAFDFLISSTILRTTLEEFVQENHVPVESVISIECIVQEPAPEPDSDIALLDWIGAIRCNDKFIASATYGGELVLWNHYGKKLTSSVLHEEAIKCLALLPDQKEDRIVTGGHDQVLMLSDVETHGSSTFIKPTCVLRGHERSVEAIAVNTDGTRTVSGGFDKMLKVWNTDKDDTSTVFEKTRSEKTGKKKRTDIITKIPMVTLSGHKDAIVSAVWSPNSAKEVLTVSWDHTISIWDLELAGQINTLAAKKAFTSISVCCSSGMLITGSVDPVVRLWDPRSHEGTLVKQSFIGHCGWISSVFWNKVKENLFISASFDKTVKMWDVRSNKTPLYDLVGHSDRILCCDWSVNELIVSGGVDCTMKTYRRKM
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ISPG_ACTP7
Sequence: MSIHQSPIKRRESKKIWVGNVAVGGDAPISVQSMTNTRTTDVEATVAQIKSLERVGADIVRVSVPTMDAAEAFKVIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRAVVDCAKDKNIPIRIGVNAGSLERDLQEKYGEPTPQALLESALRHVDILDRFNFENFKVSVKASDVFLAVESYRLLAKQIVQPLHLGITEAGGARAGSVKSAVGLGLLLSEGIGDTLRISLAADPVEEVKVGFDILKSLRIRSRGINFIACPTCSRQEIDVIATVNALEQRLEDILTPMDVSIIGCVVNGPGEALISDLGVTGSNKMSGFYLDGVRQKERFDNEKLIDQLEAKIRARVAEQHNRIQIEQI
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y376_METTP
Sequence: MNLIPIAFDSLGVRSMATCLEARGLRVMIDPAVSLGPRRYGLPPHPIELDRLNTTWQDVRGLAESSDILIVTHYHYDHHNPNDPDLYRGKIVYIKDPKNRINFSQKRRAHYFLSRIEDADIQIADGGEFGHGPLTIRFSQPVYHGTGNRLGYVIEASISCGEDKVVYTSDVEGPAMDDQVTFILEESPRTLILDGPMTYMLGYRYSEEDLRRSVNNIIKIICNTSVKTVVIDHHFMRDIGYAERIPEVYRSAEDAGVRVLCAAELIGRAPDLLEARRKELYRSSPVGEESSKQE
What are the official names of this protein?
UPF0282 protein Mthe_0376.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.
Protein: APGM_PYRAR
Sequence: MPSVLWILFDGGGDRPAGGKTPFHAAFKPTIDYLTANGSCGILDPIAPGVRPGSDTAHLALFGYDPFKYYTGRGAFEALGADVALKPGDVAFRTNLATVDENGVVIDRRAGRYIAPEEAKAVEDLMKKIGEEVGRKYGVEVVYKSTVEHRGVLVLRGAVSHRVSDTDPHKVGAKMARAEPLENSKEAALTAEVVNELSRRFTEAAAGLEINKARRLQGRLPINAILLRGGGYMPQIEPIRERYNIRAAAIAGVALIRGVARAVGMDVYTAKGLGGTKDDVFDEAVKLAVELMSRYDVVFLHVKGTDSTSHDGDFNGKVSVIERLDKALAPYLDALLKNYVVVTSDHATPVGVREHTGEPVPVMLYGPDVVVDDVAKFSELTCWRGALGRIRGIDIIPILGSYLGLSEKFGE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: SECB_NEIMB
Sequence: MSEELQPVFSIERLYVKDLSLEVPHAPQIFLEQGEPEVEMRVSTGSQKLEDGYYNVDVTVTVTAKLDNERTMFLNEVTQSGIFRLENIPEEDADLLLGVACPNILFPYAREAVSGTVTRAGFPPVLLAPINFEAIYQQQQEAEAAGA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5DNU_VIBVU
Sequence: MLQTTLKYRNRCNICVREYKCCIGSFMSRFGLSNMALTHYLTSIIHSFTSLAHQMLKRTNQDLPTPVKYYNPEIAKEYKKIEAAAEQKLLSMLPEEFQEDFRPFVISQQTSEEEAQIVKQADSICAYLKCLEELSAGNHEFALAKKRLDITLAERKTPEMDYFLNTFAPSFELSLDEIS
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase VV1_0013, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAGN1_HUMAN
Sequence: MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLLSHDQVAMPYQWEYPYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKHK
What is the function of this protein?
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function.  Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport.  Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
What are the official names of this protein?
Protein jagunal homolog 1.
What is the protein family that this protein belongs to?
Belongs to the jagunal family.
Protein: PP1_MEDSV
Sequence: MDDTVLDDIIKKLVSAKNGRTTKQVHLTEADIRQLCTSAKEIFLSQPNLLELEAPIKICGDVHGQFSDLLRLFEYGGYPPEANYLFLGDYVDRGKQSIETICLLLAYKIKYKENFFLLRGNHECASINRIYGFYDECKRRYNVRLWKTFTDCFNCLPVAALVDEKILCMHGGLSPELKNLDQIRNIARPIDVPDHGLLCDLLWADPDKDLEGWGENDRGVSFTFGADKVVEFLEHHDLDLICRAHQVVEDGYEFFAKRKLVTVFSAPNYCGEFDNAGAMMSVDDSLTCSFQILKSSDKKGKVGFGNNSSRPGTPPHKGGKN
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: TSGDD_HALVD
Sequence: MTREPFLRMENIVKAFPGVVANDHIDLTVERGEIHGLLGENGAGKSTLMKILYGLYSQDDGEISLSGTRLRLDSPQDAIDAGIGMVHQHFMLIPRLTVAENVVLGEREPATPFRPDADAGGWLPDAVRSNSLVQSLAGRFSLGLDVPERRIQELADRYGFDIDVSAKVWELGVGQQQRVEILKALYRDVDLLILDEPTAVLTPTEADLLFDSLERLTDEGVSIIFITHKLEEVEAVVDRVTVLRDGENVGTVSTSDVSRADLAEMMVGREVLFTVDRERVAPGEPVLRARNVSATDDRGIEALSNVDLTVRRGEVVGIAGVSGNGQKELAEVIAGLRTVSAGELTVDGRDLTNASPRTFIDNGVSFVPEDRNRYGSAGDLSVMHNAAMKDFREDRFGSGVTLDYGELRAHAEALVEAFDVRGVHDVTDATAGDLSGGNLQKLILAREISRDPDLLVANQPTRGVDVGAIESIREAILDQRTEGTGVVLLSEDLDEIIDLSDRILVVYEGEVVYETTPEDADRERIGLEMTGGGDATATAGAQVRGLGGSS
What is the function of this protein?
Part of an ABC transporter complex involved in glucose import (Probable).  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Glucose import ATP-binding protein TsgD13.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEMH_SHEDO
Sequence: MGHTKRNKTGVLLMNLGTPDAPTTSAVRRYLAEFLSDPRVVEIPRLLWLLILHGIILRIRPAKSAALYKGIWTEAGSPLLAISERQQAKLQGYLDEQQLTDKNGQAVSVHLAMRYGSPSVQQTMLQMHQAGIDNLVVLPLYPQYAAPTTASAFDAIAKTLSQWRYLPSLHFIHTYHDNDDYISALFASIKADFDTNGMPERLLLSYHGMPERNLHLGDPYYCFCMKTTRLVIEKMQQQGLVFDSDFVVTSFQSRFGKAKWLQPYTDVTLEALASEGVRKIAVACPAFSADCLETLEEIEQENREVFIHAGGESFRYISALNDNDDHIVMMANLVKPYL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_CHLTR
Sequence: MKHLALIGSTGSIGRQVLQVVRSIPDTFIIETLAAYGRNQEALISQIREFNPRVVAVREETTYKELRKLFPHIEILLGEEGLVSVATEPSVTMTIVASSGIDALPAVIAAIRQKKTIALANKESLVAAGELVTTLARENGVQILPIDSEHNALFQCLEGRDSSTIKKLLLTASGGPLRNKSKEELQKVSLQEVLRHPVWNMGPKITVDSSTLVNKGLEIIEAFWLFGLEAVEIEAVIHPQSLVHGMVEFCDGTILSVMNPPSMLFPIQHVLTFPERSPAIGPGFDFLSNRTLEFFPIDEDRFPSVHLAKRVLLEKGSMGCFFNGANEALVHRFLAGEISWHQIVPKLQALVDQHRVQSCLSLEEILSVDAEARARAQEC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: NU1M_USTMA
Sequence: MFSILYNLLEILVVLVPILLSVAFMTVIERKVMGSMQRRIGPNVVGYYALLQPFADALKLVIKEQVIPSQATKSLFFLAPMVTLIFSLLGWGVIPLGPGLALSDFSLGILYSLALSSIGVYGILFAGWSANSKYAFLGSLRSTAQMISYELIYSAAVLAVILLCGTFNITEIIESQQSVWYIMPLLPIFILFFVSALAETNRTPFDLPEAESELVAGFMTEHSGMIFVFFFLAEYGSIVLMSTFTAILFLGGYNMSPQVLFAEDSFINLQSIALAVKAVLIMFLFVWIRATLPRMRYDSLMTFCWTGMLPVAIALLILVPSLLIAFDISPY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNBR_AXIPR
Sequence: KESAAAKFRRQHMDAGSSSSGNSNYCNQMMKRRRMTHGRCKPVNTFVHESLDSVKAVCSQKNITCKNGQPNCYQSNSTMNITDCRETGSSKYPNCAYKTSQKQKYITVACEGNPYVPVHFDGSVFLPATPLPSLPAPHKHRLLWLEGNNSS
What are the official names of this protein?
Brain ribonuclease, BRB.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEOEP_STRFR
Sequence: MTTDIVWPPPVRQVRAYRNIVVDGACNIRCTYCEVKKTKVDQPATIRSLDRIFAEYEPDAVLFRVESDGEITLYPKIVDHLQKRAAEGYRVEVLSNGTKLPRALEGRPDLLWVFSVDGHTEAMNAKRGLKQPQIDRILDAAVELGAELQTVYWGQPVEEVNAYIDLLESRGYRGLLHFMPLLAFKGRPLTVNLRYQDLHPADFLAPPEYFRRWNHIFETGRRDAVCDQITNGYNYQVSGDEIRMVKCDCYSVPKHLVHGFGPIREFDDWPCGTCIANQEFNNSRERMRVPQGRIPLPLV
What is the function of this protein?
Catalyzes the last step of neomycin B biosynthesis, i. e.  the irreversible epimerization at C-5''' of neomycin C to give neomycin B.  To a lesser extent, is also able to convert neomycin Y2 to neomycin Y1.
What are the official names of this protein?
Neomycin C epimerase, Radical S-adenosyl-L-methionine epimerase NeoN, Radical SAM epimerase NeoN.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: RPOA_PSET1
Sequence: MQGSVTEFLKPRLVDIDAINPTRSKIVLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSAKEGVQEDIIEILLNLKGLAVTLEGKDEVFLTLAKSGVGPVTASDIQHDGDVTIANPDHVICNLTTNNSEISMRIRVERGRGYVPASSRLSSDDDERPIGRLLLDASFSPVERIAYSVESARVEQRTDLDKLIIDMETNGTLDPEEAIRRASTILAEQLDAFVDLRDVTEPEEKEEKPEFDPILLRPVDDLELTVRSANCLKAEQIQYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GATB_RHILW
Sequence: MTLVDVRTPDPKRFIPGATGDWEVIVGMEVHAQVLSNSKLFSGASTEFGKPQNSNVSLVDAAMPGMLPVINEECVRQAVRTGLGLKAQINKRSLFDRKNYFYPDLPQGYQISQFKDPIVGEGKIVISLGPDRQGQFEDIEIGIERLHLEQDAGKSLHDQHATMSYVDLNRSGVALMEIVSKPDMRSSDEAKAYMTKLRSIVRYLGTCDGNMDEGSMRADVNVSVRRPGEGFGTRCEIKNVNSIRFIGQAIEYEARRQIGILEDGGTIEQETRLFDPNKGETRSMRSKEDAHDYRYFPDPDLLPLEFDDAFVSALAVDLPELPDDKKERFVRELGLSIYDASVLVSEKAIADYFEAVAAGRDGKTAANWVINDLLGALNRTGKDIEQTPVSPAQLGAIIDLIKAGTISGKIAKDLFEIVLTEGGDPAEIVDARGMKQVTDTGAIEKAVDEIIAANPDQVEKVKAKPTLAAWFVGQVMKATGGKANPQAVQALVKAKLGIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LCPS_PYRTR
Sequence: MGFDYALVHLKYTIPPAVLLTWLYRPFFTKLDVYKVGYLVSIAVASTIPWDSYLIRTGIWSYPTHVIIGPKLCDIPLEEVFFFIIQTYNTSLLYLLLSRPTFQPVYLNTERGAARRQWRYMRLAGQVFFLALIAWGWRCIRHGGLGTYTGLILVWAGPFLLMLWSLAYQFILALPVTNTALPIFLPTLYLWVVDTLALRRGTWVISTGTKYGLHLWDGLEIEEALFFLATNALIVFGQLAFDNALAVLYTFPHLFTGPSLLPSPVLLMRALLTPCSKYHDARIKGLDEAVNRLKRKSRSFYLASATFPGPLRADLLLLYSFCRVADDLVDNASDADEARAWIAKMRKFLNNVYSDKLPQSVVHSQICDDFPPSTQSALLQLPATKLSPQPLEDLLHGFEMDLAFQQGPIIRTMEDLRVYSERVAGTVAQMCIQLIFYWYPSTLDTEEKNVIVAAGNSMGVALQYVNIARDIEVDAQIGRVYLPLNWLSEAGLSYDDVLKKPNQAQIQTLRKHLLNHAFSVYEKAKDSIERLPIEARGPIRVAVESYMEIGRILRSEQYQVKAGRATVPKSRRIMVAWRTLNSK
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LUXS_SALPC
Sequence: MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MNMA_CHLTR
Sequence: MRKTVIVAMSGGVDSSVVAYLLKKQGEYNVVGLFMKNWGEQDENGECTATKDFRDVERIAEQLSIPYYTVSFSKEYKERVFSRFLREYANGYTPNPDVLCNREIKFDLLQKKVRELKGDFLATGHYCRGGADGTGLSRGIDPNKDQSYFLCGTPKDALSNVLFPLGGMYKTEVRRIAQEAGLATATKKDSTGICFIGKRPFKSFLEQFVADSPGDIIDFDTQQVVGRHEGAHYYTIGQRRGLNIGGMEKPCYVLSKNMEKNIVYIVRGEDHPLLYRQELLAKELNWFVPLQEPMICSAKVRYRSPDEKCSVYPLEDGTVKVIFDVPVKAVTPGQTVAFYQGDICLGGGVIEVPMIHQL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_VIBVU
Sequence: MRIALGIEYNGTDYFGWQRQREVASVQEKLEKALSKVANHPVEVQCAGRTDAGVHGTGQVVHFDTNVERKMVAWTMGANANLPKDIAVRWAKAVPDEFHARFSATARRYRYIIFNHALRPGILGSGVSHYHGELDEKKMHEAGQYLLGENDFTSFRAVQCQSLSPFRNMIHLNVTRHGHYVVIDIKANAFVHHMVRNITGSLIMVGRGEQDPEWIKWLLEAKDRKLAGPTAKAEGLYLVDVDYPEEFDLPRESIGPLFLPDNLN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: AGNO_POVBA
Sequence: MFCEPKNLVVLRQLSRQASVKVGKTWTGTKKRAQRIFIFILELLLEFCRGEDSVDGKNKSTTALPAVKDSVKDS
What is the function of this protein?
Alters the structure of the nuclear envelope by interacting with host CBX5 and disrupting CBX5 association with LBR.  Involved in the perinuclear-nuclear localization of the capsid protein VP1 during virion assembly and maturation.  Plays an important role in the release of progeny virions from infected cells and in viral propagation, probably by acting as a viral ionic channel in the host plasma membrane.  Allows influx of extracellular calcium ions in the host cell.  May contribute to viral genome transcription and translation of viral late proteins (By similarity).
What are the official names of this protein?
Agnoprotein, Agno.
What is the protein family that this protein belongs to?
Belongs to the polyomavirus agnoprotein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus membrane; Single-pass type II membrane protein. Host rough endoplasmic reticulum membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Note=Mostly perinuclear.
Protein: LEUC_ALKEH
Sequence: MSGKTLYDKLWDAHVVRENPDGSALLYVDRQLLHEVTSPQAFEGLRLAGRRPWRVEANLAVTDHNVPTTNRAQGIADPVSRVQVQTLDRNCEEFGITEYGMLDRRQGIVHVVGPEQGATQPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHALATQTVVQKKAKRMLVRVDGQLGRGVTAKDVVLAIIGRIGTAGGTGYAIEFGGEAIRSLSVEGRMTVCNMSIEAGARCGMVAVDDMTIDYVRGRPFAPKGEHWDQAVAYWKTLHSDPDAEFDQVVVLDAAEIEPQVTWGTSPEMVVPVGGCVPNPFEEQDEVKRSSMGRALDYMGLQPGTPIKEIRLDRVFIGSCTNSRIEDLRAAAEVVRGHKVADSLTQALVVPGSGVVKEQAEKEGLDRVFIEAGFEWREPGCSMCLAMNADRLQSGERCASTSNRNFEGRQGQGGRTHLVNPAMAAAAAIAGHFVDVRHWPE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.