PharMolix/UniProtQA huggingface dataset:
Protein: COQ4_ZYGRC
Sequence: MLRLGVSRTPINRQFVGYEQRRHFIVASALTLGGFVFGKRAKLADAMENGELHNKNNDDEAIRKDRMDKRLKKLSETRPIKPRYEGHVPLYPHERMLLFAISGLKSFFHPEDGNNIVKLGESSAFPFVLESLKQCMLGDETGRRILREQPNITSDTLDMDRLKKMDKNSLGYTYYTWLITEGVSPDTRAPVKYIDDPLQAFIFKRYRQCHDFYHAINGLPIIIEGEIAIKALEAANMGIPMAALGALLAPLRLKPIQKERLYDIYLPWAIRTGLSCKPLINVYWEELLEKDVNELRKELGIQPPPNLRAIRQERSKIRKELKMKYDAYEVGM
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PLK4_PONAB
Sequence: MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSMEAKDLIHQLLRRNPADRLSLSSVLDHPFMSQNSSTKSKDLGTVEDSIDSGHATLSTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSSDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTFNSPSQAKTYTMERCHSAEMLSMSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQTLSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPTRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQPNTMKYMTALHSKPEIVQQECVFGSDPLSEQSKTRGMEPPLGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELLKEYASQEYVKEVLQISSDGNMITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRDRASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTYISSNSLKDCLPKSVQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPEYIKQKLQCLSSILLMFSNPTPNFH
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase.  Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit FBXW5 ability to ubiquitinate SASS6.  Its central role in centriole replication suggests a possible role in tumorigenesis, centrosome aberrations being frequently observed in tumors.  Also involved in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles.  Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1.  Phosphorylates CDC25C and CHEK2.  Required for the recruitment of STIL to the centriole and for STIL-mediated centriole amplification (By similarity).  Phosphorylates CEP131 and PCM1 which is essential for proper organization and integrity of centriolar satellites (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase Sak.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus, nucleolus. Cleavage furrow. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrioles throughout the cell cycle. Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity).
Protein: PCKG_MYCLE
Sequence: MTSATIPGLDTAPTNHQKLLSWLEEVAELTHPAQVVFADGSDEEWQQLTERLVAAGTFKKLNDEKHPNSYLALSDPSDVARVESRTFICSEREIDAGPTNNWMDPAEMRSTMTELYRGCMRGRTMWVVPFCMGPPGAEDPKLGVEITDSEYVVASMKVMTRMGTSALEKIGDDGFFVKALHSVGAPLQPGQQDMPWPCNETKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIAAGNTVFTNVALTDDNDVWWEGLEGEPAHLIDWKGNDWYAGKTETPAAHSNSRYCTPMSQCPILAPEWDDPRGVPISVILFGARRKTTVPLVTQARNWQHGVFMGATMGSEQTAAAEGKVGTVRRDPMAMLPFMGYHVGDYFQHWIDLGKHSDESNLPKVFFVNWFRRGEGGKFLWPGFGENSRVLKWIVDRIEHKAGGQDTLIGIVPTATDLDLDGLDISSDDVAKALAVDPAEWRNELPLIEEWFEFVGDKLPSGMQDEFEALKQRLAKED
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM11_MOUSE
Sequence: MALPGSLNRYLLLMAQEHLEFRLPEIKSLLSVIGGQFTNSQETYGKSPFWILNIPSEDIARNLMKRTVCAKSIFELWGHGKSPEELYTSLKSYPVEKMVPYLHSDSTYKIKIHTFNKTLTQEEKVKRIDALEFLPFQGKVNLKKPQHVFSILEDYGLDPNSIPKDPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMTNHAKVKENDLVFDPFVGTGGLLIASAHFGAYVCGTDIDYNTVHGLGKASRKNQKWRGPDENIRANLRQYGLEKFYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRSGSQKDIPKGIEKCPESHVPVSLSYHLSDMFFDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLRLISNCEQKLSSHTARRLITMEKVKEFENRDKYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKCSHE
What is the function of this protein?
Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
What are the official names of this protein?
tRNA (guanine(10)-N2)-methyltransferase homolog, tRNA guanosine-2'-O-methyltransferase TRM11 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.
Protein: YBEY_PSEPG
Sequence: MLELDIQRATDAAAPDDAAFRRWCELALRQRTADSEMTIRLVDEAEGRELNHTYRHKDYATNVLSFPADVPDDLLDIPLLGDLVICVAVVEREAAEQGKSLEAHWAHLVMHGCLHLLGYDHIEDEEAEEMEGLERELLAELGHPDPYADDETDTITH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBW_LISIN
Sequence: MATMHDKITLQLPAKPEYVSLGRLSLSGIASRAGFSYEAIEDLKIAVSEAITNSVKHAFKGEEDGEITVEYHIYEDKLEVRVSDNGTSFDLETRKQEIGPYEVGEDAEMMRIGGLGLFLIETLMDDVKLYYDEGVSVVMTKYINEKQVEENAKSIST
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: CCA_ALCBS
Sequence: MNVYLVGGAVRDSLLGLPVTEKDWVVVGATPKEMEANGFRPVGKDFPVFLHPKTQEEYALARTERKSGHGYGGFTFHAASTVSLEEDLIRRDLTINAMAQARGGEIIDPFNGRVDLKARLLRHVSPAFAEDPLRVLRVARFAARYHWLGFQVADDTLMLMKQLSDSGELGYLVAERVWKETSRALMERDPQVFFQVLHRCGALHALFPELAALDGVPQPEQHHPEVDTLLHQFLCLKQAARLGLSLNARYALLCHDLGKGKTPKEEWPRHIAHEIRSARLSKKVSKRLKVPKEAATLATLVAEFHTHSHRALELKPATVWKLFKSLDILRRPERLTDFLGACEADARGRTSFENREYPQASYLQGAADAARQVDIQALQAQGHEGPALGEAIEQARIDAIATFKQQELNP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: QCR7_CYBJA
Sequence: MASHTSIVKAGDFILRTPVLRSIFVPAAKLFCAYSGYRQLGLKFDDLIHEENPTVQKALSRLPKDEIYARNFRMLTAAQCGITHHLLSADKALKPSEDTPYLLPYLLELEAEAAERVELDNVEVAK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Complex III subunit VII, Ubiquinol-cytochrome c reductase complex 14 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRB/QCR7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PTYBC_ECOL6
Sequence: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPDIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKARQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVTADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPTATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIECMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVSGFIFTTLFGCRNVNLD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SET2_CHAGB
Sequence: MSPDDAKSAADGTSVPENGTAPKLSRKPSQKLPRGPPPLFDHLPDATADACDTFQVINDCLYGSKNMGSSDHDALDCDCAEEWHDGQNHACGEDSDCINRATKIECVSGDCNCGEGCENQRFQRKQYANVSVIKTEKKGFGLRTDADLQANDFVFEYVGEVINEPTFRNRTVKYDKEGIKHFYFMSLTKSEFVDATKKGNLGRFCNHSCNPNCYVDKWVVGDKLRMGIFATRAIRAGEELVFNYNVDRYGADPQPCYCGESNCVGFIGGKTQTERATKLPLATIEALGIDDGDSWDTAVAKKPRKKKAHEDDEDYVNSVQPRALDEDGVNKVMATLMQCKEKWIAVKLLSRLQATEDEHLRHRVVRMHGYQILKTTLNTFKDDTNVVLQILDILYQLPRITKNKISDSKVEGAVEPLASAAHEEVALAAKRLLDEWSKLETAYRIPRKKHDHAGPIPGNSFEEERRNKDREEPAKPTDPFANIVIPTGPRSTIPQRNANFFAGQQRPRKPPTNLPAGWFVNTDKTGRYYFYDATGRTQWQRPLTPAIETPKVSAKAQQDQKALQSIIDSLTKEPTPRHSAGHTPQRSTTPATEPKKDKWRSLPLEKQMKIYENTHVVDRFHGKLPKEELKKFAREVNKKLVSSDYKNNRVEDPTSIPPKQAKKVRKYAHDFFDRAVAKYTEHEKKKAHNPSKPTSGVPPGDVASSAATPAKDDVTMSDVEADTSPGSSAGRKRKRDGDDEHDDPAESPGAPPSETPSVKRIKEDDAEGEGEPTTIPPPPTPPPPPADTPPTEEDRSMREQEEALMRENEEAQRLEDEAQAEEGGKGSHEWNGRYHRTCAAGERAVEWRVGNGWCYGDDGHGRAAATTAAAAATAAAGSAGSLKTTLACFAFAPC
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EFTS_BORRA
Sequence: MSISPQEVKKLRDATGAGFGDCKKALSVAGGDFELAKKKLKEMGIVSADKRSGRDAKEGRVFSYVNTERVGLLLIACETDFVAMNSDFVAFGNSLIKQLVESGRDILDEHQELEIKNLAATIKENIYVSKVYISNIASNELVKNYLHGDHSKIGVFVKFKIDDALKMQDEKLNNFAMDLALHVAAFSPLYLSVNDICLNYIKEQEEIFMRQMESSGKPENVVKGIISGKLKKHLGEIALLEQGFVKDDKLTVKEKIEEVSKLILSKIEVVEFKYLSVG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y251_BRUSU
Sequence: MTADVPNARLVDVELDESIGRSTPDVEHERAVAIFDLIEENSFHPVGDQKGGPYRLKLSLMESRLIFSITRENGDAVATHILSLTPLRRVVRDYFMICESYYQAIRSATPSKIEAIDMGRRGLHNEGSQTLQARLKGKIEVDFDTARRLFTLVCVLHWRG
What are the official names of this protein?
UPF0262 protein BR0251/BS1330_I0252.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: COTH3_RHIO9
Sequence: MKLSIISAAFLVAITHAASIKFNVIAPNATDVKVSVNGQQVTLTASDANVPYFTGSAEVGASKTYKYVAGGTEESFDRSLDGITNSTLNDFYNRPVTYANLPQLPWPIEKDPQWTRSGSKADIFDDNYIPSVFFHGDDSQVQNVVKNVPADRISGTLTFIGSNYVYSFQNVSFGIHGAGKKHNNAKQSWNWILSGSDTMGNRNFFKLRHMEEDPTQIRERLYSDILHAMGTYANDATMVRLFINNQGFGTFNMLDDITQFSYINAKFYNGKPPATLGPLYDGASGADFLYHPGNLDGYSSWVANTANPNGEAYEALDPLCKAWNETTYTDNTAIANFEKMFDLDRFMRFMVIEYLTADWDGYWMGQTNDGAYRDPTDNNKWYFLDQDFDGTFGVNLAAPEGNAFLDVSYKDFPSRYPGAVMINNLLQNADKKATFEKYLTETVRVLFNNVTLTNRVLALHNFLLPDLEWDRSIVQQSPGINFGWTFDQVTQNLWQGVTAPNNNGGGAAFGLVEYIAAKAQAVAKEFNISIVSQPVGPPSANGTTAAAPAPAAGNSTGKGGNQSISSSASSNKTSAQSTSGASRSKTAPIVLAISALALLVF
What is the function of this protein?
Promotes invasion of host epithelial cells by adhering to receptors on the host cell surface to facilitate endocytosis of the pathogen into host cells (PubMed:24355926, PubMed:32487760).  Binds HSPA5/BiP protein on the cell surface of host nasal epithelial cells (PubMed:24355926).
What are the official names of this protein?
Invasin CotH3, Spore coat protein homolog 3.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GPI7_ASPFU
Sequence: MAFKGEHRAILIANILIVVAISIFSSGFFPYKSLLPGLATFAETNIGTVAPKVFDRVIFMVIDALRSDFVYSKTSGFSFTQSLIRSGAALPFTAHASSPTVTMPRLKAMTTGSVPSFLDVILNIAESDTSSTLAYQDTWLAQIKAQGGQLVMYGDDTWIKLFPGVFDRCDGTTSFFVSDFTEVDHNVTRHVPRELSERDWSAFIMHFLGLDHIGHKAGPKSRHMMTKQREMDSIVALIYAAMEEQEHLQSTLFVLCGDHGMNDAGNHGGSSPGEISPALLFISPKFQTKTTPEDSPVEAFSDLQYYRTVEQVDITPTLAGLLGLPIPLNSLGVFIPEFLMMWDNDAHRIDILLRNAKQMLSAMKGTFPDLDVEAITPPHGCDKHVLRSAQDVMSSTASKYNTTRLYLGLFVAALAVLLSFFPAYGLGSKYSYAVTFLMLIIISYGGMMFASSYVEEEQQFWYWVVTAWTVYLHIKSLRPWHGSKDTRRWNQTGQKFAAEPDIARDFFPRHQNILWALIILTYFDTCMHLCLNSHSSNIWRSAAILTTIAAFFFKLVFVASDSPELLYESLLSPIQKSLEEMPLVPPARLSKAVNIPIFLMFRLQAIILDFLKMSAIEVTLTSLLSQNMTFFAFGGSNAISSVDLSNAYNGIGSYSVVLVGVLTFISNWAGPIWWASAARLLYSNPTFAERYGQRTLLTFHAATSLMSVMAACTMLRTHLFIWTVFSPKYLYTLAWTILNHMFINLPATANVSQVLNWQYAFHSVACR
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI second mannose (By similarity).
What are the official names of this protein?
GPI ethanolamine phosphate transferase 2, Glycosylphosphatidylinositol-anchor biosynthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RBFA_MYCBO
Sequence: MADAARARRLAKRIAAIVASAIEYEIKDPGLAGVTITDAKVTADLHDATVYYTVMGRTLHDEPNCAGAAAALERAKGVLRTKVGAGTGVRFTPTLTFTLDTISDSVHRMDELLARARAADADLARVRVGAKPAGEADPYRDNGSVAQSPAPGGLGIRTSDGPEAVEAPLTCGGDTGDDDRPKE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_META1
Sequence: MARVIRKKPFVRRRPCQFCLKRQAVTYIDYKNEAELVRLVNMQGKILSSRITGTCARHQRAVALAIKRARYMAILPYIGLIKKDRDEIAQDQQKVEVKKMEESVKSAEPKATAEATEESKPKRTRKAKTE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LSRC_ECOHS
Sequence: MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPASSGKKREAA
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrC, AI-2 import system permease protein LsrC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MGT5A_MOUSE
Sequence: MAFFSPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRDVVDGPYAGVMTAYDLKKTLAVLLDNILQRIGKLESKVDNLVNGTGANSTNSTTAVPSLVSLEKINVADIINGVQEKCVLPPMDGYPHCEGKIKWMKDMWRSDPCYADYGVDGTSCSFFIYLSEVENWCPRLPWRAKNPYEEADHNSLAEIRTDFNILYGMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLEKRKRKKILVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGHDIRISASLAELKEIMKKVVGNRSGCPTVGDRIVELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHASYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHLNSSDIHHINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYGSSTKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNREEVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQVKLAEPGQSCKQVCQESQLICEPSFFQHLNKEKDLLKYKVTCQSSELYKDILVPSFYPKSKHCVFQGDLLLFSCAGAHPTHQRICPCRDFIKGQVALCKDCL
What is the function of this protein?
Promotes proliferation of umbilical vein endothelial cells and angiogenesis, at least in part by promoting the release of the growth factor FGF2 from the extracellular matrix.
What are the official names of this protein?
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, GNT-V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Perikaryon. SUBCELLULAR LOCATION: [Secreted alpha-1,6-mannosylglycoprotein 6-beta- N-acetylglucosaminyltransferase A]: Secreted.
Protein: AMPA_PSEA8
Sequence: MEFLVKSVRPETLKTATLVLAVGEGRKLGASAKAVDDATGGAISAVLKRGDLAGKVGQTLLLQSLPNLKAERVLLVGAGKERELGDRQYRKLASAVLSTLKGLAGADAALALGDLAVKGRDAHAKARLLVETLADGLYVFDRYKSQKAEPLKLKKLTLLADKADSAAVEQGSKEAQAIANGMALTRDLGNLPPNVCHPTFLGEQAKGLAKEFKGLKVEVLDEKKLRELGMGSFLAVAQGSDQPPRLIVLQYNGAKKDQAPHVLVGKGITFDTGGISLKPGLGMDEMKFDMCGAASVFGTFRAVLELQLPINLVGLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYAERFKPQSVIDIATLTGACIVALGSNTSGLMGNNEALVRQLLKAGEFADDRAWQLPLFDEYQEQLDSPFADIANIGGPKAGTITAGCFLSRFAKKYHWAHLDIAGTAWISGGKDKGATGRPVPLLTQYLLERAK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIMP4_BOVIN
Sequence: MPQSPRPVPSWALLLRLLALLRPPGLGEACSCAPAHPQQHVCHSALAIRAKISSEKVVPASTDPADPQKMIRYEIKQIKMFKGFEKVNDIQYIYTPFDSSLCGVKLEANSQKRYLLTGQILSDGKVFVHLCNYIEPWENLSFLQRESLNHHYHLNCGCQITTCYAVPCTISAPNECLWTDWLLERKLYGYQAQHYVCMKHVDGSCSWYQGRLPLRKEFVDIIQP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
What are the official names of this protein?
Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_HALHL
Sequence: MAGREGHFRLIAGLGNPGSKYAGTRHNAGFWLVDELVRRYGGELREEPKFRGDCARVLIDGYDCRLVKPMTYMNHSGQAVGALANFFKIPPEAILVAHDEIDLPPGSVRLKRGGGHGGHNGLRHIQSTLGTPDFARLRLGVGHPGHKDQVVPHVLSRPSPDELRQLERAIDDAADQIPRLLAGEWDRACQQLHA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.