PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_LEIXX
Sequence: MSPRALKVLEPAATDPALIRNFCIIAHIDHGKSTLADRMLQITGVVAERDMRAQYLDRMDIERERGITIKSQAVRMPWGFDGDFYALNMIDTPGHVDFTYEVSRSLAACEGAILLVDAAQGIEAQTLANLYLALENDLTVIPVLNKIDLPAADPDKYAAELAGLIGGKPGDVLRVSGKTGVGVDDLLDRVVQEIPAPVGAADAPARAMIFDSVYDSYRGVVTYVRMMDGRLGPRERIQMMSTRATHEILEIGVSSPEPTASKGLAVGEVGYLITGVKDVRQSKVGDTVTSAAKPAVDPLPGYTEPKPMVFSGLYPIDGSDYPELREALDKLKLSDAALVYEPETSVALGFGFRCGFLGLLHLEIITERLSREFGLDLITTAPSVIYEVTTEDRNVITVTNPSEYPAGKIERVEEPIVKAAILAPKDYVGVIMELCQSRRGTFLGMEYLGEDRVEIRYTMPLGEIVFDFFDNLKSSTAGYASLDYEPAGEQEADLVKVDILLQGEQVDAFSAIVHREKAYAYGTMMAGRLRELIPRQQFEVPIQAAIGARIIARENIRAIRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGRVEVPQEAFIAALSGEVGKKGKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RBBP7_RAT
Sequence: MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS
What is the function of this protein?
Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.  These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex (By similarity).
What are the official names of this protein?
Histone-binding protein RBBP7, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1844_ARCFU
Sequence: MERYPGSVMLEYMTVTAGGVNTVQITYGTEDSGNSVFQWYVNKLKSEGWEVMTSTSEGQYFVGGSKGSSYIQVEITEEAFTKISVTYTSS
What are the official names of this protein?
Uncharacterized protein AF_1844.
Protein: RK6_PHATC
Sequence: MSRIGKLPITIPENVDINYNDSEITVKGKFGTLQTQIPTVIKITESDNILTVGLSEQTRSVRALHGLYRTLINNMVIGVSEQFEIILELKGVGYRAAVQNNEIILNLGYSHPVNIKIPNIISVEVVQNTTINLKSCDKELLGLFAANIRAWRQPEPYKGKGILYKGEQIIRKAGKSAK
What is the function of this protein?
Binds 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUDC_PSEAE
Sequence: MAGEFRWQAGRPATAQVGGWVLAHCQQRFLQDDNGLLFPREWLKRQELPLLAEHGVGHWQGEPVYVLELDEPIELPGMAWAPLRQFMLHGDFDQFCMLGYASQIGIWARHNRFCGNCGTRMQAQDHERVMQCPQCGLHQYPRLSPSMIVLVTRGDEVLLARSPRFVPGVYSTLAGFVEAGESVEQCVVREVREEVGVEVANLEYIGSQNWPFPHSLMLGFHAEYVSGEIVPQEDEIEDAQWFSLDALPPLPAQRSIARHLIDLYLARRSGAAEPVLPG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: URE1_EDWI9
Sequence: MPHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIIDACLGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGASTDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFFGGGIGPTDGSNGTTVTAGPWNIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRIADKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLPSSTNPTLPFGINSQAELFDMIMICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVISMFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGNDNFRVLRYVAKITINPAIAQGVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRPMFGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNIDVDPETFAVKVDGVHATCKPVDIAAMNQLYFFG
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_PAEAT
Sequence: MSSPIKIAVTGAAGQIGYSLLFRIASGALFGGDTPVQLRLLEITPALKALEGVVMELDDCAFPALDSVEIGDDADHIFDGVTLALLVGARPRSKGMERGDLLSANGAIFTAQGKALNRVAADDVRIGVTGNPANTNALIAMSNAPDIPASRFSALTRLDHNRAIGQLAAKTHARVGDIRKMTVWGNHSATQYPDIFHAEVAGRNAAEVVNDQDWIENEFIPTVAGRGAAIIEARGASSAASAASATIDAARDWLLGTPEGDWVSMAVASDGSYGVPEGLMYSYPVTTSGGNWEIVEGLEVNDFSRRKMDATAAELFDERAAVANLGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: YR735_MIMIV
Sequence: MSSEPVTYYMIVNKSWLKIINYESPKSKRSLSGYLIKLQSNHCIEKRGYFFTDKVHLLDFIDEGDTIVSIKLPQNFDELVVVRDGKGWRSNQIIIENTSKLHDINTAKKFHIVGINDQQVANLAIKYIDVSILYYLISTGVELKSNIGYIHWWNKICMDFNNPERYFVRKLLDLTPFYVVSHGPSRNKNSQTPIRAPFETQVHNPISGQECYVQNFYFTDADRAMKFLSNGLSVFVYKIKPYLSNNDGINDIIREVRPNIFWATCVVNNGIYDLAKEDSYDSLLDLEFNIEDLTIFALKKNWAKIVYLLVSRHNFDTIFKTKLLFTAAALGYENMIYLLMKHQPIYSASQIIMGSELSSSFIMHHELDIYKVADLPVPERFIDTFLVLATVGGSIRTLTAFIKKYTEHFHKHKQIMIMYAKYYSKPDLLALFEYYSNNIVDNHITQ
What are the official names of this protein?
Uncharacterized protein R735.
Protein: VF169_ASFB7
Sequence: MNVDFIAGINNLGEKIYTCEPFKTSFQNPFIVALIITAVVLVVFFAICNPPVDKKRKTKTAIYVYICIVALLFLHYYVLNHQLNDIYNKSNMDVIVSSIHDKYKGGDEIIPPISPPSVSNELEEDQPKKIPAGPKPAGPKPADSKPASSADSKPLVPLQEVIMPSQYNN
What are the official names of this protein?
Transmembrane protein B169L, pB169L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B169L family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Virion.
Protein: MATK_IBILU
Sequence: MEEIQRYLQLERSQQHDFLYPLIFQEYIYTFAHDRGFSRSILSENPGYDNKSSLLIVKRLITRMYQQNHFIISPNDSNQNPFWARNKNLYSQIISEGFAFIVEIPFSIRLISCLEGKKIVKSQNLRSIHSIFPFLEDNFSHLNFVLDILIPHSVHVEILVQTLRYWVKDASSLHLLRFFLNEYCNWNSLITPKKASSSFSKRNQRLFLFLYNSHVCEYESIFVFLRNQSSHLRSTSSGVLLERIYFYRKIERLVNVFVKVKDFQANLWFVKEPCMHYIRYQRKSILASKGTSLFMNKWKCYFVTFWQWHFSLWFHPSRIYINQLSNHSLEFLGYLSSVRINPSVVRSQILENAFLINNAIKKFDTLVPIIPLIASLAKAKFCNVLGHPVSKPGRADLSDSNIIDRFGCICRNLSHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSEFLEQFLMSEEDVLFLTFQKASSTLRGVYRSRIWYLDIISINDLANHKSKF
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUIS_HUMAN
Sequence: MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEINWS
What is the function of this protein?
Plays an important role in the final stage of carbohydrate digestion.  Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.
What are the official names of this protein?
Sucrase-isomaltase, intestinal.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Note=Brush border.
Protein: ATPD_BACLD
Sequence: MSQSAVSKRYAAALFDIALESKLVNEIEEELTVVKKIFIEHKDLNAVLGHPKVPAEKKKQILKDSFGSVSTAVLHTLYLLVDRSRTSIVPDLADEYVKMANRFRGTEDAIVYSVKPLSEEEISSFSQVFAKEAGAASLRVRNEVNPDLIGGVKIRIGNRIYDGSVRGKLDRIERQLAGENRKKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SKG1_LACTC
Sequence: MTDGLGVSVGCAVGIPCGVAVLVAVIFWYYMQRKFKKEIEDDEESMSGDGTISFTNLHSMRVPDNPEKDLPVSHVVGGSTSSDNTTTAQNVATAGQMEAQQSQPSKKPKNTYMPAYRKRLNSSLSTLQHQDEQRSPTDSSSTSLDTKNQNGRAHSTVLDQMIPVLAQDDNAAAASSEFSLTHERTSSNDNLIKNLHNHDFGSYPKRRSSGNLTGMISGNVSSASVHTRTSSVHSGKKNNENVFDTPNSQKFHEAVAPSEEDAESKGMRSYYMLKNNYDVENASQIAEEDQYENEFTNYSESKREFINSLRPKKN
What is the function of this protein?
Plays a role in cell wall integrity.  Affects the cell wall polymer composition in the growing region of the cell (By similarity).
What are the official names of this protein?
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein; Cytoplasmic side. Bud membrane; Single-pass type III membrane protein; Cytoplasmic side. Note=Localizes on the inner surface of the plasma membrane at the bud and in the daughter cell. Localizes at an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, and a cell periphery in large-budded cells.
Protein: P4K2B_XENTR
Sequence: MEPKQTADARDSPPLLVFLEPAAEEVTAHTAPLSPNPQSARAAPGSAVRFFSDSAREEEAGEDEPLLKKSGPVSPRAARKGRTRLSSSSDRENMSGGHVGNGEFNVILDDLEFADIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVDGYKEADYWLRKFETDPLPENTRKQLQCQFEKLVILDYVIRNTDRGNDNWLIRYDSQDDDELMEKGDDFPLKDWKEIKEPVIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFVQDLCEDLYELFKTDKGFDKATFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVERSCSGSQGRIVQMSNAFTQTFHCRKPFFSSW
What is the function of this protein?
Contributes to the overall PI4-kinase activity of the cell.  This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments.  The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
What are the official names of this protein?
Phosphatidylinositol 4-kinase type 2-beta, Phosphatidylinositol 4-kinase type II-beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane. Cell membrane. Early endosome membrane.
Protein: LON_RICFE
Sequence: MNKKSLPLMALRDMVVFPGVIAPIFVGRQKSLQALSHTTVSEEDNSKYILVTLQKKFDQENPSKHELNNTAILAKIIQIVKLPNNTAKILIEAVARVKLSNIKGNDAFEANYEIIPDEEIFDVNNMRSLVDNAVQLFSKYAINDKKVNAEIIETINKEISNSTNFINIINILASHLITSLEAKQHLLEETSPFKRITTVISTLTSNIVNSETEQALQQRVRKQIEKTQRDYYLHEQMKAIQKELDEDKSELADIEKKIKSLKLSKEAKEKAESELKKLRSMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLVKSIAEGMGRKYTKFALGGVRDEAEIRGHRKTYLGSTPGKILGQLKKVKTSNPVMLLDEIDKMSSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVIFIATANSHDLPRALSDRMEKIYISGYVEEEKLQIAKNYLVPKQFKMHKIKKDEITISETAILDLIRYYTKESGVRALEREIGALTRKALKQILADKTVKHIAIDSSNLEEFLEAKKYNFGLAEKEDQIGSTTGLAYTEVGGELLTIEALAFPGKGEIKTTGKLGDVMKESAMAAYSCFRSRATNFGLKYDNYKDFDIHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVHRTVAMTGEITLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKESLEIISVSNIDQVLKHALVETPINK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTB_HAEI8
Sequence: MSLYLKAEKIQSWRVLIMACAGFIFNTTEFVPVAMLSDIAQSFDMQTADTGLMMTVYAWTVLIMSLPAMLATGNMERKSLLIKLFIIFIVGHILLVIAWNFWILLLARMCIALAHSVFWSITASLVMRISPKHKKTQALGMLAIGTALATILGLPIGRIVGQLVGWRVTFGIIAVLALSIMFLIIRLLPNLPSKNAGSIASLPLLAKRPLLLWLYVTTAIVISAHFTAYTYIEPFMIDVGHLDPNFATAVLLVFGFSGIAASLLFNRLYRFAPTKFIVVSMSLLMFSLLLLLFSTEAIIAMFSLVFIWGIGISCIGLSLQMRVLKLAPDATDVATAIYSGIFNAGIGAGALFGNLATTYLGLNEIGYTGAALGLIGFIIFITTHLKYRHTFLLQNNKKITAL
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATP_SALG2
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_BACC3
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVAQMNELGMEPIDFVIVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDVVLAELKENGEVKEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFTVTSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PSAC_CYCTA
Sequence: MAHSVKIYDTCIGCTQCVRACPTDVLEMIPWEGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: EFTS_UREPA
Sequence: MTKAELVKELRIRTQASMSECIKALDASENDIEKAIVWLRENGAIKAANKLKNAATDGVVLAKKINNKAILIEVNCQTDFVAKNENFLAYANQILEEALAKVENKEDFDKLIINGKPIAESGLDLTAYIGEKIVFRRGEILKANDDQTLGVYTHNNNRVAAIILVDGKVEDEVVRNVAMHAAAMRPRYLNEKVVDKLWLAKEREIIVNQLEHEGKPAAFAAKIIDGRLNKILKENCLVDQSYFKQPELTIEKYLKNNNAVAVGYFSYEVGEGIEKAPQMSFADEVAAQMKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_EXIS2
Sequence: MSKQYEAAGVSLTAGYESVSRMKKHVARSMRKEVMTGLGSFGAMFDLSQLNLKEPVLVSGTDGVGTKLKLAFALDQHDTIGIDCVAMCVNDIIVQGAEPLYFLDYIALGKAIPAKIERIVAGVAEGCVQSGCTLIGGETAEMPGMYADGEYDIAGFAVGAVEKQKLITGEHVQPGDVILGLASSGVHSNGFSLVRKIVAESGLRYEDELMMFGSTIGNTLLMPTRIYVEAVKAALETEKIQAMVHITGGGFYENVPRVLPEGCGATFDPKKWPTLPVFDWLEQAGNVPRHDMYNVFNMGIGYMMIVKPEDVAAVSARLARENETVYTIGTVTSEPGVRILGVDQ
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_STRCO
Sequence: MAKEKGRKLIAQNKKARHDYQILDTYEAGLVLSGTEVKSLRQGRASLADGFVQLDGHEAWLHNVHVPEYSQGTWTNHSARRKRKLLLHRVEIDKLESKSQETGHTIVPLALYFKDGRAKVEIALARGKKEYDKRQTLREKQDRREAERTISAIKRKQRA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: THIG_SHEPC
Sequence: MLKIADVEFESRLFTGTGKFSNSQVMIEAIMASKSQLVTVAMKRIDFKMGLDDLLTPLRQAGVRLLPNTSGARNAKEAVFAAELAREMLGTHWIKLEIHPDPKYLMPDAIETLEAARILCEKGFIVLPYVHADPVLCRRLEEVGCAAVMPLASPIGSNQGLVTESFLKIIIEQARVPVVIDAGIGAPSQAARAMELGADAVLVNTAIASSASPIVMAECFKEAVQCGRRAFEAGLGRVQTGAVQTSPLTGFLNQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_ERWT9
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNTGGGSNNYHHGSSPAPSSQPQQDSADAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: MTC1_YEAST
Sequence: MSENKNSEAEDVFEFLDSLPEAKNGGKMVNTDVKGSQEGVKGGSNSVAGKTGNDGKKGDDDIFEFLEELEKSNLSLTDKKGVEKKAPSESVNNKAQDEKVEESKENKNSEQDAHGKEKEPQQQEKEEEEEEEEEEEEEEEETPLHDPIASISNWWSSSGSAKVSSIWNKTAEQASQIKNRLAQEQLDLTSKINTSTITEIARNLQKIVVGETEEVLRIHLVHDLVNYPSLQYNIESKFDQVLSSQVEGGIRIFVDEWGHPNNNGITPVEKKPSVADGELGNSKKKLQFNLFDGKVTDGEKLAFANLENAVKLFNTAHEEYQKQQKEADATPDDDRSSISSNSNKISDLFISILPIAIPQKQKDADGDFQVTDSNTPGNFNFTLVLKDITNDITTITRSQGFPVKWVNWLEGSVEKTGSTASEERNKSYDQKKQKESEDEDEDDEIIDPSEWVKEWIEDGLSLSFGVMAQNYVIDRMGL
What is the function of this protein?
Involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the MTC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle.