PharMolix/UniProtQA huggingface dataset:
Protein: KDKA_XANAC
Sequence: MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFVDAPFGHSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATGQLIARFHRAGLDHADLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRAYELAWGRGY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BIOF_HALH5
Sequence: MNADWLHAIEEKLTRLKDRGSFRQLVPTSEAALPWLTRENCRLLNLASNNYLGIADSKEFIERTEQLASSYAIGSTASRLIIGNHPLYEEAEYELTKWKKTEAALIFGSGYMANVGIISSIVGRGDAVFSDKLNHASIVDGCQLSRADHLRFRHNDMDHLETLLQKSPHKQKLIVVDALFSMDGDHANLHDLVTLKERYGAILMVDEAHSGGVYGATGGGLVEELGLNDRVDIQMGTFSKALGSYGGYVAGAKPFIEYLLNHARSLIFTTALPPYIVASHLAALQIVQEQPWRREKVQVLGERLRNGLEQLGFSLCGSESYIVPVLIGDNHDLLLVSESLQAAGIAAIPVRPPTVPRGEGRIRLTVTASHTEKDIDWAIEQFQRLPLVGRRELTP
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PG148_VARV
Sequence: MTSSADLTNLKELLSLYKSLRFSDSAAIEKYNSLVEWGTSTYWKIGVQKVANVETSISDYYDEVKNKPFNIDPGYYIFLPVYFGSVFIYSKGKNMVELGSGNSFQIPDDMRSVCNKVLDGDNGIDFLRFVLLNNRWIMEDAISKYQSPVNIFKLASEYGLNIPNYLEIEIEEDTLFDDELYSIIERSFDDNFPKISISYIKLGELRRQVVDFFKFSFMYIESIKVDRIGDNIFIPSVITKSGKKILVKDVDHLIRSKVREHTFVKVKKKNTFSILYDYDGNGTETRGEVIKRIIDTIGRDYYVNGKYFSKVGSAGLKQLTNKLNINECTTVDELVDEINKSGTVKRKIKTQSAFDLSRECLGYPEADFITLVNNMRFKIENCKVVNFNIENTNCLNNPSIETIYGNFNQFVSIFNIVTDVKKRLFE
What is the function of this protein?
Plays an essential role in viral DNA replication by acting as the polymerase processivity factor together with protein OPG116.  Serves as a bridge which links the DNA polymerase OPG071 and the uracil DNA glycosylase.
What are the official names of this protein?
DNA polymerase processivity factor component OPG148.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG148 family.
Protein: ESF2_NEOFI
Sequence: MTTRKRNEFLDIVSDDDEGSDRGYDSAAAEESKGRLAKRRKTHTRADDLSDEESDFGRSESEDESKTRLKGKPKSKSQTTERSNDSDDEDEADDGEKMQVDQYLDTTAAHSPSQSRSQSPSASSVSSKPTKLKKKPLDKVRPPKKNKTGVIYLSSLPPYLKPFALKSMLETRGFGPITKVFLTPEVPSNSAPRRRSNKRKSYADGWVEFASKKTAKICAETLNATIVGGKKGGWYHDDVWNMKYLKGFKWADLMEQVQRERSEREAKRRIEDTRARKEDKVFLQGVEQGKVLQGIQKKNEEKKKKKGETGPGEGEGSADAAAAAAASELKVRRLFKQSEVKMGRDKVKDISTLEDDAKRVLSKIF
What is the function of this protein?
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis.  Required for the early cleavages at sites A0, A1 and A2 (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein esf2, 18S rRNA factor 2.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NRDR_GEOSL
Sequence: MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREPFDRLKLIAGIQKACEKRQVSRETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMSELQDLLKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FA76A_CHICK
Sequence: MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPIVKCTYCRTEFQQESKTNTICKKCAQNVKLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPHSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQCKHLSSSSRASLQEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKAKFDAISANGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADLQYQESQMRAKMNQMEKTHKEVMEQLQAKNRELLKQAAALSKGKKPEKSGAITSP
What are the official names of this protein?
Protein FAM76A.
What is the protein family that this protein belongs to?
Belongs to the FAM76 family.
Protein: PEN1_ARATH
Sequence: MWRLRIGAKAGNDTHLFTTNNYVGRQIWEFDANAGSPQELAEVEEARRNFSNNRSHYKASADLLWRMQFLREKGFEQKIPRVRVEDAAKIRYEDAKTALKRGLHYFTALQADDGHWPADNSGPNFFIAPLVICLYITGHLEKIFTVEHRIELIRYMYNHQNEDGGWGLHVESPSIMFCTVINYICLRIVGVEAGHDDDQGSTCTKARKWILDHGGATYTPLIGKACLSVLGVYDWSGCKPMPPEFWFLPSSFPINGGTLWIYLRDIFMGLSYLYGKKFVATPTPLILQLQEELYPEPYTKINWRLTRNRCAKEDLCYPSSFLQDLFWKGVHIFSESILNRWPFNKLIRQAALRTTMKLLHYQDEANRYITGGSVPKAFHMLACWVEDPEGEYFKKHLARVSDFIWIGEDGLKIQSFGSQLWDTVMSLHFLLDGVEDDVDDEIRSTLVKGYDYLKKSQVTENPPSDHIKMFRHISKGGWTFSDKDQGWPVSDCTAESLKCCLLFERMPSEFVGQKMDVEKLFDAVDFLLYLQSDNGGITAWEPADGKTWLEWFSPVEFVQDTVIEHEYVECTGSAIVALTQFSKQFPEFRKKEVERFITNGVKYIEDLQMKDGSWCGNWGVCFIYGTLFAVRGLVAAGKTFHNCEPIRRAVRFLLDTQNQEGGWGESYLSCLRKKYTPLAGNKTNIVSTGQALMVLIMGGQMERDPLPVHRAAKVVINLQLDNGDFPQQEVMGVFNMNVLLHYPTYRNIYSLWALTLYTQALRRLQP
What is the function of this protein?
Converts oxidosqualene to arabidiol.  Minor production of arabidiol 20,21-epoxide.
What are the official names of this protein?
Arabidiol synthase, Pentacyclic triterpene synthase 1, AtPEN1.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: PSBX_SYNPW
Sequence: MTPSLANFLSSLVWGAVIVVVPASIGLFFLSQTDRVDRKL
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PCRB_BACAN
Sequence: MYDISGWKHVFKLDPNKELSDEHLEMICESGTDAVIVGGSDGVTIDNVLHMLVSIRRYAVPCVLEVSDVEAITPGFDFYYIPSVLNSRKVEWVTGVHHEALKEFGDIMDWDEIFMEGYCVLNPEAKVAQLTDAKCDVTEDDVIAYARLADKLLRLPIFYLEYSGTYGDVELVKNVKAELKQAKLYYGGGISNAEQAKEMAQHADTVVVGNIIYDDIKAALKTVKAVKGE
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP) (Probable).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.  To a much lesser extent, is also able to use geranylgeranyl diphosphate (GGPP; C20) as the prenyl donor.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: RNFE_VIBA3
Sequence: MSDHKTLIKNGMWANNPALVQLLGLCPLLAVSSTVTNALGLGIATLLVLVGSNVSVSLVRNHVPKEVRIPVFVMIIASLVTCVQLLMNAYAYGLYLSLGIFIPLIVTNCIIIGRAEAFASKNEVLPAAQDGFWMGLGMTSVLVVLGAMREIIGNGTLFDGADLLLGDWASVLRIQIFQFDNSFLLALLPPGAFIGVGFLIALKNIIDNQAKSRQPKQEKPVIERARVTNA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_MICJU
Sequence: MEELQGYFEKDGSRQQPFLYPLLFQEYIYALAHDRSLNGNGSIFYEPLEIFGYDSKSSLALVKRLITRIYQQHFFLSSVNYSKQNRFVGHHHTNFFYSRFYSQMISDGFGIIVEIPFSLQLVSYLKEKEIPKSHNLRSIHSIFPFLEDKLVHFNYVSDILIPHPIHMEILVQILQCWIQDVPLLHFLRFFLHEYHNWNSFFITQNNSIYLFSKETKRLFRFLYNSYVYECEFVFVFLRKHSSYLRFTSFRTFLERRYFYVKMEHLQTEHLIIVCCDYFNGTLWSFKDPFMHYARCQGKAILVSKGTHLLMKKWKYNFVNLWQYYFYFWYQSYRIHINQLSKHSFHFLGYLSSLLKNSSTVRNKILDNSFLIDTLTTKFDTAVPVIFLIVSLSKAQFCTVSGHPISKPIWTDLSDSGIIERFGRICRNLSHYHSGSSKKQGLYRIKYILRLSCARTLARKHKSTVRTFLQKLGSRLLEEFFTEGEQDLSLILPKAILFPFQGSHRERIWYLDIIRINHLVNRS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GL8D2_HUMAN
Sequence: MALLRKINQVLLFLLIVTLCVILYKKVHKGTVPKNDADDESETPEELEEEIPVVICAAAGRMGATMAAINSIYSNTDANILFYVVGLRNTLTRIRKWIEHSKLREINFKIVEFNPMVLKGKIRPDSSRPELLQPLNFVRFYLPLLIHQHEKVIYLDDDVIVQGDIQELYDTTLALGHAAAFSDDCDLPSAQDINRLVGLQNTYMGYLDYRKKAIKDLGISPSTCSFNPGVIVANMTEWKHQRITKQLEKWMQKNVEENLYSSSLGGGVATSPMLIVFHGKYSTINPLWHIRHLGWNPDARYSEHFLQEAKLLHWNGRHKPWDFPSVHNDLWESWFVPDPAGIFKLNHHS
What are the official names of this protein?
Glycosyltransferase 8 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SPAP_SHIFL
Sequence: MLSDMSLIATLSFFTLLPFLVAAGTCYIKFSIVFVMVRNALGLQQVPSNMTLNGIALIMALFVMKPIIEAGYENYLNGPQKFDTISDIVRFSDSGLMEYKQYLKKHTDLELARFFQRSEEENADLKSAENNDYSLFSLLPAYALSEIKDAFKIGFYLYLPFVVVDLVISSILLALGMMMMSPITISVPIKLVLFVALDGWGILSKALIEQYINIPA
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the ipa antigens.  Required for invasion and for secretion of the three Ipa proteins.
What are the official names of this protein?
Surface presentation of antigens protein SpaP, Spa24 protein.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLNB_ECOLI
Sequence: MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTELYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRIRTGEEDDAAI
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of GlnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme.
What are the official names of this protein?
Nitrogen regulatory protein P-II 1.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: PSRP_ECODH
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: PG200_MONPV
Sequence: MTANFSTHVFSPQHCGCDRLTSIDDVRQCLTEYIYWSSYAYRNRQCAGQLYDTLLSFKDDAESVFIDVRELVKNMPWDNVKDCTEIIRCYIPDEQKTIREISAIIGLCAYAATYWGGEDHPTSNSLNALFVMLEMLNYMDYTIIFWRMN
What is the function of this protein?
Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B.  Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO.
What are the official names of this protein?
Protein OPG200.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG200 family.
Protein: PSBN_CABCA
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HEM3_PROM3
Sequence: MVLTQLRIASRRSQLAMVQTNWVQAELEQAHPGLSISVEAMATQGDKILDVALAKIGDKGLFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVNQKNAEHQLDTLPEGAIVGTSSLRRLAQLRHHYPHLVFKDVRGNVITRLEKLDAGNYDCLILAAAGLTRLGFGDRIHQLIPSEISLHAVGQGALGIECVEGHPEVLEVIKALEHKPTAQRCLAERALLRELEGGCQVPIGVNSRIEANELLLTGMVASLDGKRLIRDQQRGPIDRCEAIGKELAETLKSQGAGEILAEIFAAVRPEA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: FTSA_PORGI
Sequence: MSRMNTIYAVIDLGSWYIRGMVARKMEDGRVSPISFYEEPANNCIRHGCVHNIDEAAAIIRRIVNQLNENLEDNTHITSLYVGVGGQSIASQEFIVRKAMVPEGEVIRTEHIESLWAEMRGASFPDKEVLDVTDPLFYVDGKQEIQAKGVFCHELEARFQLITARRSVKQNIRIAIEERLGLRLTGILVTPLCEAQVLLSDDELTLGCCYVNIGAGCTSVSIYKNRLLAMLRVLPMGGYNVTRDLTSLRLTEQEAENMKLNHVSMINDNKSNGSFRMTFADKFSEREFRSSEVNRLAKARMDEITANYLNILRLSGLLEDIGAGIILNGGGTKINNYMAAMKKILGEVTPAKIRMDRIDTDNAISFIEEHISTIGLAYKATQPCTDYITTNLGELVSQIETKEEIPANDTVQDLFAQGRQTERKENEQRDNTDRQREDTPKQTVKKKEKTGPSFGDKLKGAFIKFGSLFDEDTNQDNNR
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: MYC1_SOLLC
Sequence: MTDYRLWSNTNTTNTCDDTMMMDSFLSSDPSSFWPASTPNRPTPVNGVGETMPFFNQESLQQRLQALIDGARESWAYAIFWQSSVVDFASQTVLGWGDGYYKGEEDKNKRRGSSSSAANFVAEQEHRKKVLRELNSLISGVQASAGNGTDDAVDEEVTDTEWFFLISMTQSFVNGNGLPGLAMYSSSPIWVTGTEKLAASQCERARQAQGFGLQTIVCIPSANGVVELGSTELIFQSSDLMNKVKYLFNFNIDMGSVTGSGSGSGSCAVHPEPDPSALWLTDPSSSVVEPKDSLIHSSSRDVQLVYGNENSENQQQHCQGFFTKELNFSGYGFDGSSNRNKTGISCKPESREILNFGDSSKRFSGQSQLGPGPGLMEENKNKNKNKKRSLGSRGNNEEGMLSFVSGVILPTSTMGKSGDSDHSDLEASVVKEAVVEPEKKPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAIAYINELKSKVQNSDLDKEELRSQIECLRKELTNKGSSNYSASPPLNQDVKIVDMDIDVKVIGWDAMIRIQCSKKNHPAARLMAALKDLDLDVHHASVSVVNDLMIQQATVKMGSRLYAQEQLRIALTSKIAESR
What is the function of this protein?
Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736).  Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626).  Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371).  Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371).  Involved in type VI glandular trichome development (PubMed:30518626).  Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626).
What are the official names of this protein?
Transcription factor MYC1, SlMYC1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MAEL1_DROPE
Sequence: MAPKKRNGFMTFVKEWQANNPVARGLSNSEAVAKCDPIWKSMGDQERGPYNSMAKNANVLERTAKKERLNCLGGSVAEMEIEKNEAISAELQMKRKIERIILTAKNSMELENEDFVFVSFNYFTKALTGDIYVPAEFSACRYSLKGGISSNYSTMINPGHIIYGQSRDAQDHSKTTHKLPLPPQAFGETNMGKLYIDIFNWLSVRNEEKLDQDPVIVYTTPELMPVVKSCFRYLASEAEIDEDERKIMVFDIHHLFYTLKKSVLDVAGVTNDRINFHVTNNFFVKDFFEYTEGISCDYHEKIDRSKYCTNSMVKRWGFTFSDYMCADLAIPLQPGKHIPLKVKPNYTITPASSSTNFDEISLDSYYSAPPRIQKEMGSRDLSPSSSHQSVSRAYVPRDHSVYGGTLDSDEEFPSLGGRRRQLPDKSHFNMGAGKKIAR
What is the function of this protein?
Involved both in the piRNA and miRNA metabolic processes.  As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons.  As a nuclear component, it is required for proper differentiation in the germline stem cell (GSC) lineage by repressing microRNA-7 (miR-7), thereby acting as an indirect regulator of bag-of-marbles (Bam).  Acts by binding to the promoter of miR-7 gene and repressing its expression; miR-7 repression alleviates the Bam repression by miR-7, thereby allowing differentiation in the germline stem cell (GSC) lineage (By similarity).
What are the official names of this protein?
Protein maelstrom 1.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
Protein: MOBA_BACCN
Sequence: MKSVAGIVLAGGMSRRFGEPKALVSWQGYTFIERIVQVMQDVMQDIVVISHASIKERVAHLIEVPVIEDISFYKGEGPLAGIVSGMEHLEAEWYMISPCDTPNISSKWIKQITGQIDDEYEAIIPIVEGRKQPLLGAYHKNVKEKIYKLLDEEKRSMEQLLSHCNVKYVTGDEWNIEKTWFVNVNTKEEYAELLTCKKK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNW_BURPS
Sequence: MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALAASDIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFTPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: MSHC_RHOOB
Sequence: MQSWSETAVPSVPGQGPPLRLFDTADRQVRPVTPGRTATMYVCGITPYDATHLGHAATYLTFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWVVLGMRETALFREDMEALRVLPPRDYIGAVESIGEVIEMVEKFVASGAAYVVDDPEFPDVYFRADATEQFGYESGYDRATMDTFFAERGGDPDRPGKQNPLDALVWRAARPGEPSWPSPFGPGRPGWHIECSAIALNRIGSGFDVQGGGSDLIFPHHEYSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLVFVSKLRGEGVDPAAIRLGLLSGHYRQDRPWTEQVLADAHTRLQLWKDAAALESAQSATDTIARLRQHLADDLDTPKALDALDGWARRALDNGGSDTNAPTEFAAAVDALLGVRLRRP
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: PR8A9_MOUSE
Sequence: MVLPLSQPHFSGALLLLVVSNLLLWEKASAIPACMAQKSGCWNPLVETFNSAMQTAGTLRTLADQFYVELYHNQFSSGQFLIFNSNLIRRDETVARAGTYCHSTLSNPPDRGTEHADAETEKYLKTLINYVGAWIGPLYHVVIELNVMQDVPETILSKVRQIEENKRKLLEDLRWILTKVYPTAEMKEEFPAWEHLSFLKSQGKHYKLLAMFNLSNCIYNETYHILFYLRELKCQITGEDC
What are the official names of this protein?
Prolactin-8A9, Placental prolactin-like protein C2, PLP-C2, PRL-like protein C2, Prolactin-like protein C-beta, PLP C-beta.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y300_CHLMU
Sequence: MARKERLTNEKLNKLFDSPFSLVNYVIKQTKNRIARGDVRSSNVAIEALNFLDLYGIQSECLERDDREQYASGAGEKRKEQSSGNSRRKDPSLYNWSDVK
What are the official names of this protein?
Uncharacterized protein TC_0300.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0121/CT_031/TC_0300 family.
Protein: SEPF_PAEAT
Sequence: MAGALRKTMIYLGLADGDEHYESEQSVATHHDEERPQAQEREERRAPAPVREVVREMPTVDAEEEYRAPVTPIKRAASSREDASGLRQITTVHPRSYNDAKVIGESFRDGIPVIMNVTDMGEADAKRLVDFSAGLVFGLHGSIERVTNKVFLLSPSYVEVIGDDKKASETQASFFNQS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: ATPG_HYPNA
Sequence: MPSLKDLKNRIGSVKSTQKITKAMQLVAAAKLKRAQEAATAARPYAERLAAVLANLAATTGQGGPKLLTGNGTDQTHLLVVMTAERGLAGGFNAYVAKLARLKIQQLQSEGKTVKVLTIGKKGREVLAREHSALFTGHVNLSDVKSNNFTDASLSVGQMLTKGFENGEFDVATLIYSQFKNVLSQVPTAQQLIPATAPEGAPVIDLGGAQYIYEPSEEALLEALLPRYINTQILSAMLESSAGEQASRMTAMDNATRNAKDLIKALNLKYNRARQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KTHY_ANAMM
Sequence: MFITFEGIDGCGKTTQAVLLAKYLSDLYGEHRVVLTREPGGTSLNELIRGALLGLTDYKLDGITELMLFIAMRRESFVKVVLPGLLAGKIVISDRFTDSTVAYQGYGCGVDLALVGMLNSLVADVVPDITFVIDASIELALARTSLNGFENHGPEFYDRVREGFRTIVANNPHRCHMIDCKSDAAEDVYSTHDRIVALFRAITQDKLKVAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.