PharMolix/UniProtQA huggingface dataset:
Protein: EFG_SINMW
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKGRDGKSRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRSVEMIKTRLGATAVVMQLPIGAESDFKGVVDLIEMNALIWRDESLGAQWDVVEIPDDLKEKAEEYREKLIETVVEIDEAAMEAYLEGQYPDNEQIRALVRRGTIDVKFHPMFCGTAFKNKGVQPLLDAVVDYLPSPVDIPAIKGIDVKTEAEIERHASDEEPLSMLAFKIMNDPFVGSLTFARIYSGKLEKGTSVMNTVKEKRERVGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKQVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDEESGQTIIAGMGELHLDILVDRMRREFKVEATVGAPQVAYRETITRQHEEDYTHKKQSGGTGQFARVKIVFEPNPEGEEFKFESKIVGGAVPKEYIPGVQKGIESVLSSGPLAGFPMLGVKATLIDGAFHDVDSSVLAFEIASRACFREAAKKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQIQGQEARGVAVVINAHVPLANMFKYVDNLRSMSQGRAQYTMLFDHYAPVPSNVAQEIQAKYSGQK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_SALEP
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_LISIN
Sequence: MKALKIALTKGRLEKDAVALLEKAGIDCSSMNDKKRKLIFHSSTQPISFILVKAVDVMTYVKHGVADIGIVGKDVLMEASKSHYEMLDLEIGQCQFCLASTPDFDPSSYRRKIIATKYPAVSSKFFRAKGEDVEIIKIEGSVEIAPVLGLADAIIDIVETGSTLKENGLVIYEKMYPISARLIVNKASLKQNKTQIFQLIDQLEQAIKEEQTR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBBA_BACVZ
Sequence: MFHPIEEALEALKKGEVIIVVDDEDRENEGDFVALAEHATPEVVNFMATHGRGLICTPLSEDIAGRLDLHPMVDHNTDSHETAFTVSIDHRLTKTGISAQERSFTIQALLNEESVSDDFQRPGHIFPLIAKKGGVLKRAGHTEAAVDLAKACGSQGAGVICEIMNEDGTMARVPELAEIAERHQLKMITIKDLIEYRYNITTLVNREVDITLPTDFGTFRVYGYTNEVDGKEHLAFVMGDVPFNSEPVLVRVHSECLTGDVFASHRCDCGPQLHAALAQIAEEGRGVLLYLRQEGRGIGLINKLKAYRLQEQGYDTVEANEALGFLPDLRNYGIGAQILRDLGVQHMKLLTNNPRKIAGLEGYGLSISERVPLQMEASEHNKQYLQTKMKKLGHLLHF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: VINT_BPML5
Sequence: MARRGWGSLKTQRSGRIQASYVNPQDGVRYYALQTYDNKMDAEAWLAGEKRLIEMETWTPPQDRAKKAAASAITLEEYTRKWLVERDLADGTRDLYSGHAERRIYPVLGEVAVTEMTPALVRAWWAGMGRKHPTARRHAYNVLRAVMNTAVEDKLIAENPCRIEQKAADERDVEALTPEELDIVAAEIFEHYRIAAYILAWTSLRFGELIELRRKDIVDDGMTMKLRVRRGASRVGNKIVVGNAKTVRSKRPVTVPPHVAEMIRAHMKDRTKMNKGPEAFLVTTTQGNRLSKSAFTKSLKRGYAKIGRPELRIHDLRAVGATFAAQAGATTKELMARLGHTTPRMAMKYQMASEARDEAIAEAMSKLAKTS
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: UTER_HORSE
Sequence: MKLAITITLAILALCCSPASAEICQSFADIIQGLFLGTPASFEAAVEPFKPDADMKAATTQLKTLVDFLPKNTKDSILKLMDKIAKSPLCA
What is the function of this protein?
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
What are the official names of this protein?
Uteroglobin, Secretoglobin family 1A member 1.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_RAT
Sequence: MAGEKAEKPDKKEQKPAAKKAGGDATAPRALPAGAVKKSSSKAKKLRKSKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTKTVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLIILTGRHRGKRVVFLKQLGSGLLLVTGPLALNRVPLRRTHQKFVIATSTKVDISKVKIPKHLTDAYFKKKPLRKPRHQEGEIFDTEKEKYEITEQRKADQKAVDSQILPKIKAVPQLQGYLRSQFSLTNGMYPHKLVF
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L6, Neoplasm-related protein C140.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: URE2_HAEI8
Sequence: MIPGEYQLAEGDILANVGRKTVKIEVTNSGDRPIQVGSHYHFFETNNALKFDRTLARGMRLNVPSGNAVRFEPGEVKSVELVAFGGNQIIYGFHNQIDGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUS_ECOL6
Sequence: MARYDLVDRLNTTFRQMEQELAAFAAELEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNFSQAALVSHIQHINKLKTTFEHIVTVESELPSAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_ESCF3
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDAD2_ARCFU
Sequence: MALIPKEVFFVSGVGRHEDELVSFELALRDAGIERFNLVPVSSIVPPGCRVVSKEEGLRKLSPGQIVFCVMARYASNVEGREIFASVGAAFPEDKDMNGYIAEHSGEWYEGAEQHAKRLAEEMLKTQGSKVARTFAITARGKVKEFTTAVAAAVFVI
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase 2, PvlArgDC 2.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: ADHA_ACEAC
Sequence: MTRPASAKRRSLLGILAAGTICAAALPYAAVPARADGQGNTGEAIIHADDHPENWLSYGRTYSEQRYSPLDQINRSNVGDLKLLGYYTLDTNRGQEATPLVVDGIMYATTNWSKMEALDAATGKLLWQYDPKVPGNIADKGCCDTVNRGAGYWNGKVFWGTFDGRLVAADAKTGKKVWAVNTIPADASLGKQRSYTVDGAVRVAKGLVLIGNGGAEFGARGFVSAFDAETGKLKWRFYTVPNNKNEPDHAASDNILMNKAYKTWGPKGAWVRQGGGGTVWDSLVYDPVSDLIYLAVGNGSPWNYKYRSEGIGSNLFLGSIVALKPETGEYVWHFQATPMDQWDYTSVQQIMTLDMPVKGEMRHVIVHAPKNGFFYVLDAKTGEFLSGKNYVYQNWANGLDPLTGRPMYNPDGLYTLNGKFWYGIPGPLGAHNFMAMAYSPKTHLVYIPAHQIPFGYKNQVGGFKPHADSWNVGLDMTKNGLPDTPEARTAYIKDLHGWLLAWDPVKMETVWKIDHKGPWNGGILATGGDLLFQGLANGEFHAYDATNGSDLYKFDAQSGIIAPPMTYSVNGKQYVAVEVGWGGIYPISMGGVGRTSGWTVNHSYIAAFSLDGKAKLPALNNRGFLPVKPPAQYDQKVVDNGYFQYQTYCQTCHGDNGEGAGMLPDLRWAGAIRHQDAFYNVVGRGALTAYGMDRFDTSMTPDEIEAIRQYLIKRANDTYQREVDARKNDKNIPENPTLGINP
What is the function of this protein?
Dehydrogenase component of the alcohol dehydrogenase multicomponent enzyme system which is involved in the production of acetic acid and in the ethanol oxidase respiratory chain.  Quinohemoprotein alcohol dehydrogenase (ADH) catalyzes the oxidation of ethanol to acetaldehyde by transferring electrons to the ubiquinone embedded in the membrane phospholipids.  The electrons transfer from ethanol to membranous ubiquinone occurs from pyrroloquinoline quinone (PQQ) to one heme c in subunit I (AdhA), and finally to two heme c in subunit II (AdhB).  Besides ubiquinone reduction, ADH also has a ubiquinol (QH2) oxidation reaction which mediates electron transfer from ubiquinol to the non-energy generating bypass oxidase system.  The electrons transfer occurs from ubiquinol (QH2) to the additional heme c within subunit II (AdhB).
What are the official names of this protein?
Alcohol dehydrogenase (quinone), dehydrogenase subunit, ADH, Alcohol dehydrogenase (quinone), acceptor subunit, Alcohol dehydrogenase (quinone), subunit I, Ethanol:Q2 reductase, G3-ADH subunit I, Quinohemoprotein alcohol dehydrogenase, Quinohemoprotein-cytochrome c complex, Ubiquinol oxidase.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Periplasmic side.
Protein: METXS_XANCP
Sequence: MVRIVPSARRTRAPAKLDGRSTPDIAMSLVTTASPLTTADTYTPAADSDAPPAVRGELVINLPMRHAGQRELRLRYELVGAEQAPVVFVAGGISAHRHLAASAVFPEKGWVEGLVGAGRALDPASRRLLAFDFLGADGSLDAPIDTADQADAIAALLDALGIARLHGFVGYSYGALVGLQFASRHAARLHTLVAVSGAHRAHPYAAAWRALQRRAVALGQLQCAEHHGLALARQFAMLSYRTPEEFSERFDAPPELINGRVRVAAEDYLDAAGAQYVARTPVNAYLRLSESIDLHRIDPAAVAVPTVVVAVEGDRLVPLADLVSLVEGLGPRGSLRVLRSPFGHDAFLKEIDRIDAILTTALRTTGETA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BUCBP
Sequence: MVNLGKDTYPVYIGSNLLEISNIFFPIESNTQVAIITNDVVFKIWNKKITYYLHKLGAQVKNVIISDGEIYKNIDTVEIILSTLLKYSYCRDAVLIALGGGVIGDITGFVASIYQRGIKFVQIPTTLLAQVDASIGGKTSVNHVLGKNMIGSFWQPSSVIINFDFLNTLPRRQLISGIAEIVKYAVSFDVNFFNWLEENLERVLKLDYSALSYCINRCCEIKISIVEKDEKEIHDRMLLNLGHTYGHAIETFLGYGTWLHGEAVSVGIVMASKTSELLGFMKDNDITRIISLLQRVGLPISGPKNMSFESYISNFKRDKKVISGKLRMVLPVFIGNVKIFSNVHENILMSVIKNC
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNJ_THET2
Sequence: MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLAFPEEGMPGVDLLIPRVDYLIEHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYGARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFTLDLFRMTHSIPDNSGVVIRTPIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAKELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLKVKDRLYTLEEVKDLPDHQVLILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPIPGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEELKLILNLTTPRFFLPWHGEVRHQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEILADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKPLERIRDDIYYPVKKFLKKATGRDPMILPVVIEG
What is the function of this protein?
An RNase that has endonuclease and possibly 5'-3' exonuclease activity.  Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
What are the official names of this protein?
Ribonuclease J, RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM10_DEBHA
Sequence: MSQSFPRNDTSSSSEDETDNYRSHIQIPSLDLANYRKQQKSTSKTNLAKAGKKLKNNKSVRFPDSYSPRDTIISNASTTNNSSSDSELEQDMVTGENSNLPNFNFSANQVHSPEYANEDDANDDSGEEEDTFEPPADFYASEGSDEDMEADNEGDNVEDKEEVVNEKEEIADDLHSKSSKTSRESKSFNAGTKNSRRSLNSLQRNETDVTDQLKRTTSTTSSSKRSNSDKRTGFKDILRKFALVDQQYPEAPSNRESEDLGEPQPSRSDTFLGNVLSMAGESGGLVPGATHFSREKTIDEEEEVGFEDEDSDLIEMKKLDFAQLSNEAQNLISTHVPDLANKLPEGTSSDQQLDYSDTSASNLIKNDEETGNEATKKDDEFYTPNPDYFIRGDINNENDADDYLMLDEHMDDIAPPKRVQAGVLSSLLKLYQNPQEQQSSSSLTSKSTYGGNTLADDSNYSYSDPKAASTLDFTKLKNDFKNGPKRMANKIPGRKHGAQKQDTQDESAQKYYDEDGNEIAAPNLPSFHNAKPKAPKKIAAAGKVPSKVHKKLKEHKRQQDQQLRITVHIADILHRQRFIMRMCKALMMFGAPTHRLEEYMTLTSRVLEIDGQFVYFPGCMIVSFGDASTRTSEVHLVRCAQGLNLSKLSDTHRIYKGVIHDILPVDEASTQLEELLKKKNRYSPWLCVFLYGLGSSMVCPFAFNGGWYDVPIAFGVGLCVGYLQFFVSSKSNLYSSVFEVTASIVVTFIARAIGSIHDGEYFCFSAIAQGSLALILPGYIILTGSLELQSRNIVAGSVRMFYAIIYSLFLGFGITLGASLYGWVDSNAISTTKCKNSIKQDEFKILFVPLFSACLGLINQARWRQLPIMIVIACAGYVGTFFAGKHKQFSEVTEFTACIGAFIVGILGNLYSRIGKGMAVAAMLPAIFVQVPSGIASQSTLLAGVESADKLTSSNSTTTDTSTASDSAGSLAFGATMVKVSIGISVGLFASALFVYPFGKKKTGLFSL
What are the official names of this protein?
Pheromone-regulated membrane protein 10.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TLR2_SHEEP
Sequence: MPRALWTAWVWAVISVFTEGASDQASSLSCDPTGVCDGHSRSLNSIPSGLTASVKSLDLSDNEITYVGNRDLQRCVNLKTLRLGANEIHTVEEDSFFHLRNLEYLDLSYNRLSNLSSSWFRSLYVLKFLNLLGNLYKTLGETSLFSHLPNLRTLKVGNSNSFTQIHEKDFTGLTFLEELEISAQNLQLYVPKSLKSIQNISHLILHLRQPVLLLDILIDIVSSLDYLELRDTNLHTFYFSEASISEINTSVKKLTFRNVQFTDDSFVEVVKLFNYVSGILEVEFDDCTHDGVGDFTALTLNRIRYLGNVETLTIRKLHIPQFFLFYDLSSIYPLTGKVKRVTIENSKVFLVPCLLSQHLKSLEYLDLSENLMSEETLKNSACEHAWPVLQTLVLRQNRLKSLEKTGELLLTLKNLNNLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTQCLPQTLEILDVSNNNLDSFSLILPQLKELYISRNKLKTLPDASFLPVLSVMRISGNIINTFSKEQLDSFPQLKALEAGGNNFICSCDFLSFAQGQQALARVLVDWPDGYRCDAPSHVRGQRVQDARLSLSECHRAAVVSAVCCALFLLLLLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPRRDLCYDAFVSYSERDSYWVENLMVQELEHFNPPFKLCLHKRDFVPGKWIIDNIIDSIEKSRKTIFVLSESFVRSEWCKYELDFSHFRLFDENNDAAILILLEPIDKKAVPQRFCKLRKIMNTRTYLEWPTDETHREAFWLNLRAAIRS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: PSAI_PIPCE
Sequence: MTDFSLPSILVPLVGLVLPAIAMASLSLHVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SECA_ERWT9
Sequence: MLIKLLTKVFGSSNDRTLRRMRKAVEQINKMEPDFVKLSDDELKAKTIEFRARLEKGEELEALIPEAFATVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRALFEFLGLSIGINLPGLPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLNYALVDEVDSILIDEARTPLIISGPAEDSSELYIKVNKIIPNLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLVAVEELMVSEGIMAEGESLYSPGNIMMMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVDIQNENQTLASITFQNYFRLYNKLAGMTGTADTEAFEFSSIYKLDTIVIPTNRPMVRKDLPDLVYMTEMEKIGAIIEDIRERTANGQPVLVGTISIEKSEVVSQELTRAGVKHEVLNAKFHAREADIVSQAGQPGAVTIATNMAGRGTDIVLGGSWQAEIAALEDASAEQIDAIKAAWKIRHDAVLASGGLHIIGTERHESRRIDNQLRGRSGRQGDHGSSRFYLSMEDALMRIFASDRVTNMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETIASIREDVYKTTIDSYIPPQSMEEMWDVAGLQERLSNDFDLTLPIADWLVAEPNLHEETLRERIMQQAQEQYQRKEEVVGVEMMRSFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVVSTLSKVQVRMPEEVEQMEEQRRQESERLAQQQQLSHVDAETEAAQSLAEQSGERKVGRNDPCPCGSGKKYKQCHGRLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CRBA2_MOUSE
Sequence: MSSAPAPGSAPVCLTLWDEEDFQGRRCRLLSDCANVCERGALRRVRSVKVENGAWVAFEYPDFQGQQFILEKGDYPCWSAWSGSSGHHSNQLLSFRPVLCANHSDSRVTLFEGENFQGCKFELSDDYPSLPSMGWTSKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFRTYSDFGTQAHTGQLQSIRRVQH
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A2, Beta-A2 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: KGUA_PSEA6
Sequence: MPQSLGNLFILAAPSGAGKSSLIKALLQNHDATEIHNNEMQVSVSHTTRAPRPGEIDGVHYHFVSRKVFQELITQDEFFEWAEVFGNYYGTSKVVIEQTLRKGIDVFLDIDWQGARQVKAQIPDTATIFVAPPSREELMRRLTERGQDTPEVIQDRMNKAVSEISHYHEFDYIVVNDDFTAALAELDAIVSSRRLRKEKQVMRHQSLFENLLASD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDX_SULTO
Sequence: MVWKRTISAKALEKAKSAAVKVDDKVIFIANVNGNLYAMDAVCSHARCILGKLDEEKLTVRCYCHLALFDLRTGQMLEPPYVAPDAPKEKLGLKTYQIRDNNGWIEVDV
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Sulredoxin, Pink FeS protein.
What is the protein family that this protein belongs to?
Belongs to the SDX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPAP3_RAT
Sequence: MTSTSKAVELQLQVKHNAEELQDFMRDLEHWEKTMRQKDLELRRQSGVPEENLPPIRNGSFRKKKKRKTKDSSKKTKEENTKNRIKSFDYDAWAKLDVDSILDELDKEDSTHDSVSQESESDEDGVRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRSYTKAYARRGAARFALQKLEDARKDYVKVLELEPDNFEATNELRKIDQALTSKENSHPKDIAAVIKPAEGERKANEDQRGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADSTNALLPANRAMAYLKVQKYEEAERDCTQAILLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAVTELSRIKKELIEKGRWDDVFLDSTQRHNVVKPVDSPHRGSPKALKKVFIEETGNLIESVDAPESSATVPESDRAAVAVDTGRKKDFSQGDSVSSGETPRAKVLKIEAVGDSSAPQAQVDVKQGVRQSVSEKTSVRVAQTPGQLAAVVLPPVPANSFQLESDFRQLRSSPEMLYQYVKKIEPSLYPKLFQKNLDPDVFNQIIKILHDFYVEREKPALIFEVLERLSQLRRFDMAVMFMSGTERELTKVLFNHLEKSELKEDSVEELKKRYGGG
What is the function of this protein?
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
What are the official names of this protein?
RNA polymerase II-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the RPAP3 family.
Protein: PEBA_SYNPW
Sequence: MFDSFLNKLHQGIHQRGGQPAAVPEGLEHCHSSKSGGSIDSWLWSVPGFRRWRVTRLDAGESLQVLNSVAYPDHSLDHPLMGVDLLWFGARQKLVAVLDFQPLIQDQDYLDRHFQGLKALHERFPELNGEETMRSFDPNQYFSPWLLFCRGGAQEAEESLPAAFDAFLTAYWAMHDQALDVEAAGTSASTLSINDVERLQEAYDVYSAERDPAHGLFTSHFGKDWSDRFLHEFLFPASQST
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: AMDA_BORBO
Sequence: MQQASTPTIGMIVPPAAGLVPADGARLYPDLPFIASGLGLGSVTPEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAALTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGCRSLGITGVEAMARVDTATLVDLCVRAFEAAPDSDGILLSCGGLLTLDAIPEVERRLGVPVVSSSPAGFWDAVRLAGGGAKARPGYGRLFDES
What are the official names of this protein?
Arylmalonate decarboxylase, AMDase.
Protein: ILVD_METS3
Sequence: MKSDNIKKGIQRAPHRSLLRACGLGDNDFDKPFIGIANSFTEIVPGHIHLRELVEFVKEGIIAAGGIPFEFNTMAICDGISMNHEGMKYSLPSREIIAATVESMAKGHSFDGLVLMPSCDKVVPGMLMGAARVDVPTIVVTGGPMAAGQYKGKNADLITVFEAVGQESAGKISEEEVYEIEKCACPGAGSCSGLFTANTMACVTETLGLSLPFCATTHAADKANEKMAYNSGKQIIKLVEADLKPSDILTQEAFNNAITVDMALGGSSNTALHIPAIANEVEDVEVTLDLFDKISRVVPHICLISPAGTDTMMDLHKAGGIPGVLKTLGDKIDTSAITVTTKTLGENIKDVEVTNTDVIHPLDNPIHKDGGIAILKGNIAPNGSVVKKGAVSPDLMHLKGPAKVFNSEEEVTQAIFDHEVEEGDILVIRYEGPKGGPGMREMLNPTSALAGMQIKNVGLITDGRFSGGTRGPCIGHVSPEAMSDGPIGAIEDGDIIEIDIENRFINVELSDEEISNRLANRKNPKRDVDGWLSIYSKVVQSADTGAILR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL33_CHLTE
Sequence: MAKGKENRIVITLECTEAKKEGVPVSRYTTTKNKKNTTERLILKKYNPNLKRHTEHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.