PharMolix/UniProtQA huggingface dataset:
Protein: WECF_ECOLU
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNMMANDRQRKGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLALFSEENLQILNEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NDHK_LUPLU
Sequence: MNSIEFPLRDRTTQNSVISTTLNELSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAIGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISREIYEKQIRSQRENKNRFFTTNHKFHVGRSTQTGNYDQGFFFQPPSTSEISLTHFSNIKKRVQYPPTK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: GLMU_RALSO
Sequence: MNIVILAAGLGKRMRSALPKVLHPLAGKPLLAHVIETARSLSPTRLVVVVGHGGDRVRDMVGAPDVTFATQDQQLGTGHAVMQALDQLDDTVPTLVLYGDVPLTRAETLNALVGAAGQDHLGVLTVHLDDPTGYGRIVRDATGRITRIVEQKDANETQLAIHEVNTGILVCPTARLKTWLATLRNDNAQGEYYLTDVIERAASEGLPITSAHPLAEWETLGVNSKVQLAELERIHQRNLAQQLLEDGVTLIDPARIDIRGRLTCGRDVVIDIDCIFEGNVTLGDGVRIGAHAVIRDAAIQAGAEILPFCHIEQATVGAQSRIGPYARLRPGTELAEDVHIGNFVEVKNSQIAAHSKANHLAYVGDATVGSRVNIGAGTITCNYDGANKFRTIIEDDAFIGSDTQLVAPVRVGRGATLGAGTTLTKDAPEGQLTVSRARQTTVNGWQRPVKQKKDA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_STRPI
Sequence: MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TRHO_RICM5
Sequence: MNEKIAILSAYSFVNIEEPANLIPKLLLIGKRKYVRGTILLANEGFNGSFSGSYENVNLVLEELIKLTGPKDVNVKINYSDVHPFQKLKVRLKKEIVAMNVDDLNVDLFKGEYIEPKDWDEFITKQDVIVIDTRNDYEVEVGTFKSAINPNTKTFKQFPAWVQQNQELLKGKKIAMVCTGGIRCEKSTSLLKSIGYDEVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVTDDLSPVERHWLQR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RUVB_PHEZH
Sequence: MSRIVSGEAQPFEPADRALRPQTLSEFVGQEQAKANLSVFIDAARGRGEALDHVLLFGPPGLGKTTLAQILARELGVNFRATSGPVLAKAGDLAAILTNLEPRDVLFIDEIHRLAANVEEILYPAMEDHVLDLVIGEGPSARSVRIDLAPFTLVAATTRAGLLATPLRDRFGIPVRLEFYTHDELARVLLGAAAKMGAPLDPSGAREIAARARGTPRVAGRLLRRVRDFAAADGAEVIDRKAAAAALARLDVDEVGLDALDRRYLRALIENYAGGPAGVETLAYAIAEARDAVEDVIEPFLLQQGFIQRTPRGRMACAKAYEHLGLQAPRNLGGAAPPADLFDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ENV_HAPV1
Sequence: MSVNRSSIKSLLMVFMIVSSSLLAPVGGAAADEFRTPAASDTSPEAGECSNLDDFIMFLSVGRINADSCSRQAYVDAAVQDMKDSDANQTKVDIYSAAAGVKGGSETWAAPYDNYLNDTESIAWMKAESAIAQSYSEGESKTEAKVAAKAAIADYYATKQKNLIEQWNFANAQMFTLREQARMEDGISRNYVEPAYRNVEKTNSPDYSLAYSNTTVEKSLVDGTTVNTTGVSMDVTVQHTTVSDVATVSSGPVRAGKYNNQYNEWKATYYSWSVEPASPSQDTLYAVHFQPYADRWQRIVDMNGALQSEADNFVNATWDDYDTGQINASDVLSANTAMSEYGVRSGSESEGLWRSTAALSMMGYDTPNLNNSGMMTVEYKNVQHTGLLMAKNAPNGSWQVNTTYNTSNIDGPVFMATTEGTKLDFADGEEFTIVGMTAKDGTAVNSTQTTKYRYKTANTTELLEVQNQLIELRQEIEDREPEAGGFFGSGSTDTMLVGLLALAGVLLLAQSNNRGGRR
What is the function of this protein?
Envelope protein that may play a role in host-cell attachment and viral genome entry.
What are the official names of this protein?
Envelope protein, Env, Virion protein 4, VP4.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: HYPM_HUMAN
Sequence: MSEKKNCKNSSTNNNQTQDPSRNELQVPRSFVDRVVQDERDVQSQSSSTINTLLTLLDCLADYIMERVGLEASNNGSMRNTSQDREREVDNNREPHSAESDVTRFLFDEMPKSRKND
What are the official names of this protein?
Huntingtin-interacting protein M, Histone H2A.P, Huntingtin yeast partner M.
Protein: MURG_ANOFW
Sequence: MKIVVSGGGTGGHIYPALAFIHEVKKQHPNVDVLYIGTKKGLESTIVPRENIPFHAIDISGLKRSLSFENVKTIVRFIKSVRACKKLLKQYKPDVVLGTGGYVCGPVVYAAAKLGIPTIIHEQNSIPGLTNTFLSRYANKVAICFEETKQYFPQEKVVLTGNPRASEVVGKDGREARRSLGLDEKKKTVLIVGGSRGARPINEAFLQVLHEVEQKPYQCLYVTGDVHYDKVMKAVNDVGNPSNVIIRPFIHNMPEVLAGVDVIVARAGATTLAEITALGIPSILIPSPYVTNNHQEKNARALEKKGAAIVRLESELTGVRLLDDIDRILLNEQTLTNMKEAAFQLGIRDAAERLYRVMVEMIS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YBEY_PECCP
Sequence: MSQVILDLQIASEQAQGLPEEKDFQRWLEGVLPQFQEVSEVTIRIVDEAESRDLNNTYRGKDKPTNVLSFPFEAPPEVELPLLGDLIICRQVVEQEAAEQEKTVEEHWAHMVVHGSLHLLGYDHIEDSEAEEMEALETEIMQSMGYADPYLAEKDGLTE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2239_MYCBO
Sequence: MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG
What are the official names of this protein?
Epimerase family protein Mb2239.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: RNY_STAAM
Sequence: MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y, Conserved virulence factor A.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PAN2_RAT
Sequence: MNFEGLDPGLAEFSPAMHSTLDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLQEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDESEDMHSLLLADNNTLLVGGLQNHVLEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRSFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPALDWSQDLLPLSLIPVPLTTDALLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDHEFDNFSQVTESPTGREEEPLHTVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGSNFLRAFRTIPEASALGLILADSDEASGKGSLARLIQRWNRFILTQLHQDMQELEVPQAYRGAGGSFCSSGDSIIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPEDKTGKNYDFAQVLKRSICLEQNTQAWCDSCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRLQAEVAFKIAVKKFGGEVKSKEFALADRKELRSPEGFLCCSSMEELKNVWLPFSIRMKMTKNKGLDVCNWADEHELSSLGTPSQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKYEAVQFDMNWKVPAILYYVKRNLNSRYNLNSKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGAEPESFHKVLKGLYEKGRKMDWKVPEPESQSSPKSKAGLRPGALGWVG
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  Also acts as an important regulator of the HIF1A-mediated hypoxic response.  Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit Pan2, Inactive ubiquitin carboxyl-terminal hydrolase 52, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: YC82_SCHPO
Sequence: MAANISKLEAIIDNTPNSSPDPEVSHKLWVSSLNKFQYTLPLLISNFAGLGIAFIYCLIAFIREMSHPSSRKDTMEHGLPIILCSTLMLVGNILYYFLSKHPLKVTVPEDLVQIPMQQMSSPAQEAP
What are the official names of this protein?
Putative uncharacterized membrane protein C622.02.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y960_HELPJ
Sequence: MLINAVIEKDENGYFAFVPFLKGCVSQGKSYEEALRNIKEAIELYLGDLEADELAFLSKKNSVIAPIEIAFA
What are the official names of this protein?
UPF0150 protein jhp_0960.
What is the protein family that this protein belongs to?
Belongs to the UPF0150 family.
Protein: YGCS_ECOLI
Sequence: MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
What are the official names of this protein?
Inner membrane metabolite transport protein YgcS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KHSE_LACAC
Sequence: MIIKVPASTANLGPGFDSIGMAVSLYLEVEVLSVSDRFQVDHVIPKIPHDETNLIVKTALTVYPGLQPLHLRVKNDIPLAHGLGSSSSAIAAGIELADHFGKLGLSDEEKVQIGARIEGHPDNIAPTILGGLVVGTEVDQHFDAIKAPLPPYTLVAYVPDYNLATKDARKVLPKELDFKTATHGSAIANTLVASLFTQNYKMAGELMESDVFHEPYREKLVPELNQIREVAHQKHAVATYLSGAGSTVMTWIEDEHVRGFLSGLNKHGLKANTFILHPDKNGVQIIE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_STRPB
Sequence: MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKGQVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGGPELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHNELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLANDPAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYPGYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQELYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLGESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDDMLDRYLPKADTTMTKVFVAND
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: TRHO_ECOSE
Sequence: MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYDFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPTE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis.  May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LAT52_SOLLC
Sequence: MAKAIVLLSALCILALANFAHCRPEVFDVEGKVYCDTCRVQFETKLSENLEGATVKLQCRNISTEAETFSVEGVTDKDGKYKLTVNGDHENDICEVTVVKSPREDCKESVSGYEKARIECSDNVGIHNAVRFANPLFFMKAESVQGCKEALDELGLFPLEF
What is the function of this protein?
May play a role during germination or early tube growth.
What are the official names of this protein?
Anther-specific protein LAT52.
What is the protein family that this protein belongs to?
Belongs to the Ole e I family.
Protein: ATP8_TETNG
Sequence: MPQLNPSPWFAIMVFSWFVFLIFLPPKIMAHTFPNEPTAQSTQTLKTKSWTWPWH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: LSHR_BOVIN
Sequence: MGRPSLALRLLLALLLLPPPAPLLWALRPAPCPEPCSCPPDGALRCPGPQAGLSRLSLTYLPIKVIPSQAFRGLNEVIKIEISQSDSLEKIEANAFDNLLNLSEILIQNTKNLVHIEAGAFTNLPRLKYLSICNTGIHKLPDVTKIFSSEFNFILEICDNLHITTIPRNAFQGMNNESITLKLYGNGFEEIQSHAFNGTTLISLELKENARLEKMHNDAFRGATGPSILDISSTKLQALPTYGLESIQTLIATSSYSLKKLPSREKFTNLLDATLTYPSHCCAFRNLPTNEQNFSFSIFKNFSKQCESTARRPNNETLYSAIFAESELSGWDYDYGFCLPKTLQCAPEPDAFNPCEDIMGYNFLRVLIWLINILAITGNVTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDAQTKGQYYNHAIDWQTGSGCSAAGFFTVFASELSVYTLTVITLERWHTITYAIQLDQKLRLKHAIPVMLGGWLFSTLIAVLPLVGVSNYMKVSICLPMDVESTLSQVYILTILILNVMAFIIICACYIKIYFAVQNPELMATNKDTKIAKKMAVLIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPVNSCANPFLYAIFTKAFQRDFFLLLSKFGCCKYRAELYRRKDFSAYISNCKNGFTGSNKPSRSTFKLTTLQCQYSAVLDKTCYKEC
What is the function of this protein?
Receptor for lutropin-choriogonadotropic hormone.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
What are the official names of this protein?
Lutropin-choriogonadotropic hormone receptor, LH/CG-R, Luteinizing hormone receptor, LSH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROE_HALWD
Sequence: MDIYGLIGNPVEHSLSPPMHEAAYDARGIDARYVTFEPTKDTLETAINGANALDIAGINVTIPFKQDVLNHIIPDDIAREVGAVNTIKFHDGETPRGYNTDVAGVKRAFQHHNISIDGYDAVVVGAGGAGRAAAFALADAGAHVHIANRTVERAETIATDIGGQATAGGLDTRDEISDADILLNATSVGMDPDSNQTPVPQSYLHDGLVVLDAVYTPIETRLLREATAAGATTIDGAWMLLYQGVVAFEIWTEQDAPIQQMNAALRAELEDA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MUTL_SHESH
Sequence: MTIQILPPQLANQIAAGEVVERPASVIKELVENSLDAGATRVDIEIEKGGSKLIKIHDNGSGISKEDLGLALSRHATSKLSSLDDLDAILSFGFRGEALASISSVSRLTLTSRTADQVEAWQAYAEGSDMAVKVIPAAHPVGSTVEAVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALVRSDIHFTLKHNGKVVRNYRATNTQDQYLQRLAQISGKKFAEQAIEINCQHDDLKLTGYVQSPFFETPASDTQYFYVNGRLVRDRLVNHAVRQAFAEHETGEQASYVLMLELDPHQVDVNVHPAKHEVRFHQSRYVHDYIFQALQSALHQVGRLAIDSDNKLDTDSHSQSHERGHSAYGVAEPSHSRHDYSHQTAPSTKASTETNRERFSSPISAVPSHTSDVQSRGGATSSYRQQAELPSAAAIASYAELLKTPDVDQGNRGNKELQANVSMPPILAGQYWVLTQEEQLLLLPVRIISTWLLQHEISNKLDSGLVSQPLLMPVSISMDETWSDTLAERELLLRKIGIEVTIRLGQLIIKKVPPYLRQSQLVAVIPDLLQWLRFEEPSNEALASWLAKHDDKRFESAPDTWLAFSQLDDNVQDELIKKAKVLPWQSWLEEYPSD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: COAD_DESHY
Sequence: MRIAIYPGTFDPVTNGHLDILKRATEFFDEVIVAVAVDSNKTTLFSLEERIQLLETAAEELSQVKIRGFEGLTVEFARQCGANAIIRGLRAMQDFEYEFQLALMNKKLAADIETIFLMTQSEFSFISSSSIKWAASLKGNISEFVPPHVERAIYKKYHPEIDD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_PROM5
Sequence: MRQHVNPLSKNFFEIDPIPPLNEVFENPQLPLHLDIGCASGDFLMELSLKNKNWNYIGIEIREKLVLNANLKIKNREYKNVYFSFGNAINILNNTNNKTLIDAITSISFYFPDPWFKKKHHKRRVIQPEFINLLSNAMRTRSLIFIKTDVQELFEYMELTILESLKFKKLAYEDFRVNESFNPIKTQTKREKYVLLSQFEIYESIYIRI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: F170A_HUMAN
Sequence: MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCVSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVNKEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQCPGCVFHSPKDRNS
What is the function of this protein?
Acts as a nuclear transcription factor that positively regulates the expression of heat shock genes.  Binds to heat shock promoter elements (HSE).
What are the official names of this protein?
Protein FAM170A, Zinc finger domain-containing protein, Zinc finger protein ZNFD.
What is the protein family that this protein belongs to?
Belongs to the FAM170 family.
What are the subcellular locations of this protein?
Nucleus.