PharMolix/UniProtQA huggingface dataset:
Protein: VPS10_VANPO
Sequence: MLLSQWLLTTCILISSYVHAADQFKPKVVRTESTGWFNIYPFDDSKVILKNEDTFLSISDNNGETWRPIEGINDVRWSWIDKLYPKTRAFANSKVGNKIYMTDDQGKTWTTVKINEKEYSNGSKSELSCNLISHPTKPEILLAECYVCDYDEEQSNGSITKRAVSSLFDNFLNSIMRDPTCRNEVFISTNSGKDFTKLNIDLKEREESNLLYSTLNCQFAIASKQSKNTETDSTIYCTRKHFYGQKFNDKNEADKTYLVSSFVKTSNWGKTFEELPELKGYLVNYFEAFDSQLLVITQDDAYNRHSTQKVWISKDFKTFKEAHMPTQLRFMINGLISEDSVGRLTMPILRTNPDKKDSSDKNEDNKKMHHTDSVVSDILISDSRGTKFTFIEWMNSNDVTYRQISSFKYLKGTLFGHTQEYPNLGNKGPSFEMILRSKVSVDNGNTWSNLKIVDPENKSKYSCNIDIPESCSLNIMSMFGTPDFITPGIMMVNGAVSDGHHASWNETKTFISRDGGVSWKLAFEFQTATAFGDHGNVIVAVPYDPESDDDPQSEFYYSLDQGTTWTEYQLEKTILPMQLISTTPDGSGLTFILNGLSMDSTGGSRWRWNDKKETNFVYSIDFSDAFEEKACVDSDLEKWYVAGGNCINGAKYRFDRRRADSKCLMRKIYDDLAYTEEICEKCSDDDYECSYEFVKDSSGKCVADFELLSLSGSCAKAKNGKISLKPKQRIVNTLCKVDMKIEDVLVPCTEVDSPENPDNIITVSENKFDSALLTYKYFDTASDESLLMMTLDNEVYVSHDGGKNIKKVNTNREKIVEIVFNPFYSKDAYLFGRDGGLYITHDRGQTFTKSQLPETRQLGLKLEFHATKQNTFIYYGGKDCDSMFSEKCHAVAYITTDGGETFSEMLNNGIHCKFSGSTFKDPYNEDQIICQILDSSNGKKKLVSSTNFFKSDSQTETLFEEVIGFMSTGEFLVVALPHGDDELRAYATLDGKEFAEANLPKDLSDIKQESFTILGSESGSIFMHLATSQNIQGEFGRLLKSNSNGTSFVSLESAVNRNSAGFVDFEKIQGLEGIVLINVVENTDEVERGTTKTKKLKSKITFNDGSDWSFINPPLKDSNGKKYTCSGKGLKKCSLHLHGYTERNDIRDTFSSGSAFGMLIAVGNVGEHLLPKDECSTFMTIDGGATWTEVRKGPFQWEYGDHGGILVLIPDGSESDTLLYSTDFGKTWIDYKFAGEKIQMRDIVTVPRDSAMRFLIIGQSNSIRGGTTTVFSVDFSKIFSRQCVYDLDNASNDDFEFVSFNPVKNQCLFGHQAEYLRKIHTDCFIGSAPLEESFRIVKNCSCTRNDFECDYNYYKANDGTCKLVEGLTPSDPKDICKKNPDAYEYFKPTGYRKIPLSTCVDGLNLEGTSSPLPCPGKVEEFRKNHKINGRSFSLLFILPFLILLGIAWFIYDRGIRRNGGFSRFGEIRLGDEVIEENNVDKAVNNIVRTGLLLTSSVFSGLQLVKRFIGKSFQSLRERVTGRRGPSYTTLFNDQFLEGADDLLEGHDEDANDLTSFLSNDNNFDIDTEDDGNTFAPFREEASEEDHGPVTGDSSNNEEVSS
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: DRC5_MOUSE
Sequence: MQETPSVPSNSSSHSQSVLTIQRQVSALGSSSTGPTSLKTSSTPTPGQLKTKVPNVRRMRRIISEDAEWSLAIVPLLTELCIQHIVKNFQNNPILKQLPLEHQKKVLSNLPPELPLTVTANLIDDENYWHRCCIKRWSVCHVSRHGGSWKRMFFERHLENLLKLFIPGTTDPNVILDLLPLCRNYVRRIHVDQFLPPVRMPTPLQGEEQSDSGSEGEGSEPEKDHYQLQTLVGGLKHLEELDLVYGVKDCGMNFEWNLFLFTYRDCYSLAATIKACHTLKIFKLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLNLANNQLQAPGAQSLAHALAHNTNLVFLNLRLNCIEDEGGQAIAHALETNKCLSVLHLGGNKLSEPTATLLSQMLTVNTTLVSLNLSCNHIGQDGGKQLLEGISDNKTILEFDLRLSDVSQESEYLIGQVLHANREAARQRTLNPGHFSSPTNNCTENSVV
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  May play a role in the assembly of N-DRC (By similarity).  Required for sperm motility (PubMed:28630322).
What are the official names of this protein?
Dynein regulatory complex subunit 5, T-complex-associated testis-expressed protein 1, Tcte-1.
What is the protein family that this protein belongs to?
Belongs to the DRC5 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Detected along the length of the sperm flagellum.
Protein: MURI_ACTP7
Sequence: MKPTILLYDSGMGGLTIYDAIRQTLPNAHYLYCFDNAYFPYSERSENVLIEQAVKIVQKIAEKYPLDMVVVACNTASTVVLPALREKFAFPIVGTVPAIKPAAAISQTKTIGLLATKGTVERPYVAELIEKYAKDCIVEKIGTTTLVELVEEKIRTGNVDQDRLSKVVAEWQTHPTLDTVILGCTHFPLVKQELQQLLPKVKFFIDPGNGIANRVATLLSEFSLENSAQNKENIAFCTKMDEEFSKREIIMQQWGFKRLELLNLSQK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PSBB_OENGL
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTVTNPGIWSYEGVAGSHILFSGLCFLAAIWHWVYWDLAIFSDERTGKPSLDLPKIFGIHLFLSGLACFGFGAFHVTGLYGPGIWVSDPYGLTGEVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGAGLAKNQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDSGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTIEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDTQVEFGAFQKLGDPTTRRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KLRA5_MOUSE
Sequence: MSEPEVTYSTVRLHKSSGLQRLVSHEEIQGPGEAGYRKCSVPWQLTVRSLGIFCFLLLVTVAVLAVKIFQYSQHKQEIHETLNHNHNCSNMQSDIKLKEEMLRNKSIDCSPGEELLESLNREQNRWYSETKTDLDSSQDTGTGVKHWFCYGTKCFYFIMSKNTWSGCKQTCQHYSLPLVKIEDEDELKFLQFQVISDSYWIGLSYDKKKKQWAWIDNGPSKLDMKTRKMNFKPGGCIFLSKTRLEDTNCNNSYFCICGKKLDHFPG
What is the function of this protein?
Receptor on natural killer (NK) cells for class I MHC.
What are the official names of this protein?
Killer cell lectin-like receptor 5, Lymphocyte antigen 49e, Ly-49e, T-cell surface glycoprotein Ly-49E.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RS10_CHLT3
Sequence: MAVQQKIRIKLKSYDHSLVDKWAEKIIEAVKQTDAIISGPIPLPTESQVFTVNRSPHVDKKSREQFMVASHKRLIEIINPSSKTIDLLMKLELPSGVDVEIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MACD2_XENLA
Sequence: MYQSNKKKRLWKEEKERLLNMTRDERRKEYREYVSLDKIPSLMEELKSKASSDDESPEEIQVKNSLCEKVSFYKGDITQLEVDAIVNAANTSLLGGGGVDGCIHRASGPSLLAECRELGGCETGQAKITCGYELPAKYVIHTVGPIARGHITPNHKQDLASCYNSSLTLATENDIRTIAFPCISTGIYGYPNEPAANVALTTVKEFLKKNRDKIDRVIFCVFLEVDFKIYKRKLNEFFPKDGGDDEEGEKGDSDEMKEDTEGKPQSPPMKKIKEKKEDTPAPDSPDEEYSAEEATGNTQDMTAMSLETNEGNDVSSPATDPLKEGEELSEAKITGEKISVEPKTPEPEDAKMTVEEKSQEQEDSENMETSQPKVSGETEDLDGDSEEPSDVQKEIASPSNETCQESDPKDTNDDANEA
What is the function of this protein?
Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety.  Inactive towards proteins bearing poly-ADP-ribose.  Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.
What are the official names of this protein?
ADP-ribose glycohydrolase MACROD2, MACRO domain-containing protein 2, O-acetyl-ADP-ribose deacetylase MACROD2, [Protein ADP-ribosylaspartate] hydrolase MACROD2, [Protein ADP-ribosylglutamate] hydrolase MACROD2.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins.
Protein: TPS16_SOLHA
Sequence: MLSLYEAAQFRVHDEEILDEALKFTTTHLKLILPELSNSLLAQQVGNALKFPIKDGVVRVEARKYISFYQQNQNHNQVLLNFAKLDFNILQMLHKKELCDITRWWKELEIVKALPYVRDRLAEVYFWSLGVYFEPQYSTARKILTKNISMISLIDDTYDIYGTLDELTLFTEAIERWNIDASEQLQLPSYMKIIYCGLLDVYDEIKKDLANENKSFLINYSIIEMKKMVMAYFQEATWYYGKTIPKMEQYMKNGISTSAYVQIAATSWLGMGNVATKDSFDWIVNEPPILVASSIIARLLNDLLSHEEEQKRGDAPSSVECYMKEYGVTKEEAHIKIRNIIENSWKDLNEEYFKVNGTIIPRVLLMCIINLARVIEFIYKDEDAYTFSKNNLKDVVYRILIDPII
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21818683).  No activity detected with geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) as substrates (PubMed:21818683).
What are the official names of this protein?
Sesquiterpene synthase 16, ShTPS16.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: SYD_CLOBM
Sequence: MGEALRGLKRTIMCGEPRENNIGQKVTVMGWVQRKRNLGGLIFVDLRDRTGIMQIVFGEEINKEAFEKSDNVKSEYCIAVTGEIVKRQSPNNDMETGAVELKGEDIKILSESETPPIYIKEGLDASENIRLKYRYLDLRRPDMQKIFMIRHKTCKVVRDFLDENGFLEMETPILTKSTPEGARDYLVPSRNYKGMFYALPQSPQIFKQLLMVSGYDKYFQITKCFRDEDLRANRQPEFTQIDMELSFIEEDDVIELNERLLAKVFKEVAGIDVKLPIERMPYKIAMEKYGSDKPDLRFGMEINDLTEAVKNSEFKVFKGAIEAGGSVRAIKAGNCATMGRKQIDKLQDFVKTYKAKGLAWIAYKEDEIKSPIAKFLTEEEMKAILEKMDAKVGDLILIVADKNNVVFESLGALRLHLAKELDIINKDEFRFVWITEFPLLSYNEEEGRYQAEHHPFTALMDEDVELLDTDPGKVRAKAYDIVLNGEELGGGSIRIHDSKLQEKMFNVLGFTKEKAWERFGFLLEAFKFGPPPHGGLAYGLDRMIMFLAGTENIKDVITFPKNQNAFCPLTEAPNVVDENQLEELGIKKIEKED
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM86B_PIG
Sequence: MDPGKEGLPRKPRFSAQQLHVGKWLSPFFFTCAVYFLLWIPDDQPSWVGALVKCLPVLSLVVFLRAVDAGGGYSARLQGALLCSAVGDACLVWPEAFLHGVAAFAAAHLLYLWAFGLTPLQPGLLLLVILAALPYYGLLLWHLPPDLVLALTAYSLALATMLWRGLARGGSTGWGALLFTLSDTTLAWNAFAQPLPHARLVVMTTYYSAQVLISLSVSQSPKLKPN
What is the function of this protein?
Enzyme catalyzing the degradation of lysoplasmalogen.  Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens.  May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties.
What are the official names of this protein?
Lysoplasmalogenase, Transmembrane protein 86B.
What is the protein family that this protein belongs to?
Belongs to the TMEM86 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm.
Protein: GRAP_DROME
Sequence: MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTPYHS
What is the function of this protein?
Adapter protein which modulates signaling mediated by several receptor tyrosine kinases such as sev and Ack (PubMed:8462097, PubMed:22615583, PubMed:8462098).  Required for proper signaling by sevenless (PubMed:8462097, PubMed:8462098).  May act to stimulate the ability of Sos to catalyze Ras1 activation by linking sevenless and Sos in a signaling complex (PubMed:8462097, PubMed:8462098).  Required for functional and morphological integrities of the scolopidia, sensory neurons and the antennal mechanosensory and motor center (AMMC) brain neuropil (PubMed:30610177).  Required for Ack-dependent suppression of apoptosis in the eye (PubMed:22615583).
What are the official names of this protein?
Growth factor receptor-bound protein 2, Downstream of receptor kinase, Protein enhancer of sevenless 2B.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Synapse. Note=Localizes at the presynaptic terminal.
Protein: IF1C_CHAGL
Sequence: MKKQNLIEMEGIVTESLPNAMFRVSLDNGCQVLAHISGKIRRNYIRILPGDKVKVELSPYDLTKGRITYRLRMKTTNG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YO11B_YEAST
Sequence: MESQQLSNYPQISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIINRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-OL Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UVRC_STAAN
Sequence: MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRL_SALNS
Sequence: MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNVKPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTAVPINETEVVERLEYTLREFHEKLRDLLISMELALEPSDDFNDEPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_STRA3
Sequence: MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDRNGRVGFGTGKAQEVPEAIRKAVEAAKKNMVEVPMVGTTIPHEVRSEFGGAKVLLKPAVEGAGVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISVSDLA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LUXS_PHOV8
Sequence: MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAATYLRNHPIWSDKIVYWGPMGCLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAAPKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTKE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: DNJB7_HUMAN
Sequence: MVDYYEVLGLQRYASPEDIKKAYHKVALKWHPDKNPENKEEAERKFKEVAEAYEVLSNDEKRDIYDKYGTEGLNGGGSHFDDECEYGFTFHKPDDVFKEIFHERDPFSFHFFEDSLEDLLNRPGSSYGNRNRDAGYFFSTASEYPIFEKFSSYDTGYTSQGSLGHEGLTSFSSLAFDNSGMDNYISVTTSDKIVNGRNINTKKIIESDQEREAEDNGELTFFLVNSVANEEGFAKECSWRTQSFNNYSPNSHSSKHVSQYTFVDNDEGGISWVTSNRDPPIFSAGVKEGGKRKKKKRKEVQKKSTKRNC
What is the function of this protein?
Probably acts as a co-chaperone.
What are the official names of this protein?
DnaJ homolog subfamily B member 7.
Protein: RGS19_BOVIN
Sequence: MPTPPEAEKQQTGPEEADQPPSMSSHDAAPPAPPRRNPCCLCWCCCCSCSWNEERRRAWRASRESRLQPLPSCEVCATPTPTPTPTPEEVRSWAQSFDKLMHSPAGRSVFREFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPAYRALLLQGASQSSSEA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2.  Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 19, RGS19.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: UVRC_ECO57
Sequence: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity).
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4424_ARATH
Sequence: MHLINAVAAARILSGIGQSNGNNGGEAIPFGSFEWITYAGISCFLVLFAGIMSGLTLGLMSLGLVELEILQRSGTPNEKKQAAAIFPVVQKQHQLLVTLLLCNAMAMEGLPIYLDKLFNEYVAIILSVTFVLAFGEVIPQAICTRYGLAVGANFVWLVRILMTLCYPIAFPIGKILDLVLGHNDALFRRAQLKALVSIHSQEAGKGGELTHDETTIISGALDLTEKTAQEAMTPIESTFSLDVNSKLDWEAMGKILARGHSRVPVYSGNPKNVIGLLLVKSLLTVRPETETLVSAVCIRRIPRVPADMPLYDILNEFQKGSSHMAAVVKVKGKSKVPPSTLLEEHTDESNDSDLTAPLLLKREGNHDNVIVTIDKANGQSFFQNNESGPHGFSHTSEAIEDGEVIGIITLEDVFEELLQEEIVDETDEYVDVHKRIRVAAAAAASSIARAPSSRKLLAQKGTGGQNKQGQTNKVPGQEQDKMLGTITEPIRRNN
What are the official names of this protein?
DUF21 domain-containing protein At4g14240, CBS domain-containing protein CBSDUF1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: F261_BOVIN
Sequence: MSQEMGELTQTRLQKIWIPHNNGNSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALLIRKQCALAALKDVHSYLSHEEGRVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDVIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDDELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIQSQGISSLKVGTSHMKRTIQTAEALGLPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, 6PF-2-K/Fru-2,6-P2ase 1, PFK/FBPase 1, 6PF-2-K/Fru-2,6-P2ase liver isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: Y309_ENCCU
Sequence: MRMWLVSAIALVDILCTSKIEELVENMGKKIEEALPHEFDSAEKEALKKHLKETAGLGTRLMVPCIFHEDRVVASPTTRYQDIDEEEKGYVEKVIALLPRLLWRSVAYIYVFGNDSWVVNLMEEVFETAPFKKSDAVALYKRARGRLGIRLIDLVNRTFRHNIGMLNRFGQRLAQEAEAKIQEISSSLSDEEKRKEEKMLQIIKEYGESLCTKEKQEEIIRAQEIMCDACACIWERDSNRESFVMETYSRHLYLRMIGSSMDVEEPLLSYIDHRGLIDAYEKYKSIDIVAELIKQVFTERGCISDESVNDAVCGVREREEAEKMRGEEERRKKEEESLRNTLELLRMEEKEKSKSRGKKKKGGKKGSGEVTAKMEEEKKDSEEVEESAEAEVSLEEMAVGGARSKERSSKKKSRSKGHRYKVHKRVLRWTKSAERIKAELDEGSEEKWRNKSIEEIEEQKKVHDIIEVCVLLRSLDANRFFVSTNRYMKDGTERWKMVGVGIFEEGGEKKVGKVEVGLYRDKGEGSVIYHLMFKAMDTEKAGKGARSSFGKGDDVEGLEEGAGELSDMSGFEYPKGVRSEIVKGGDAFKIVYRNPKDTSEVLRSLTVLQKAEVL
What are the official names of this protein?
UPF0329 protein ECU03_0090.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: TO1F_HADIN
Sequence: MNTATGFIVLLVLATVIGCISADFQGGFEPYEEEDAERIFRRSPTCIPTGQPCPYNENCCSQSCTYKTNENGNQVKGCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hi1f.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.