PharMolix/UniProtQA huggingface dataset:
Protein: RTTN_DROME
Sequence: MSTKQSPALQLAEGQLTKLTSESEEIRMRALDQIETRFIRCLQLGEPIQFKPVLLLKQLIRWFGYTPPLVPDRVLAMIMELLRSEYAEAVIRKIPYERFKAELQKVRRVLHKQESKRVSELLDDMNLLLLEKYNIDRVTPSVSSLSSNDIPSQATESADSSSNQIYDNLKPEDYEPSWSHPCLDDVATMKSMIDLPRNSVELQLQLTELIIRMGDYPTEYFLQPPFVFLHLVQLQTMTDGSLIHVNRALIACLRLLQQRILLRRNTLSYADRFDPPSRPKQVKVVSALVILLENCMKLIRPLLFSCTNDNWHIMELIVEIVRTHDVLSSKIPLVSITLIADAVKSLLAYCNSVEGSCMTQLMDSLRIPRLQSLILNGVLHDMVALNINYDKRMDRRQAKALIQPIVLDSAYLSGMPERMKSLNTLISSLDSGPSPDEELIKLKRAYSVALNQLHPNTELTGSLLIQKYRQVCLVLVQLGSETLVKQLFGAVVKCIPFYAGNLKLRKDADELLYTLVDLPALKLRSLIYRLMIKSTVAHFHSFMNKTVYMTGCSNVDLIRQHILGVPLTPLLLRRMIIQSSEANTSERMQQWCLDYPIMIMKLNAILAPQDFSVVFPLLLPVLPLLISRSVTHKILHNVIWNVLEPDSSRLDPQLMLRGYVYFMFHPDGEVRSEATTTIAYVLQCQEQTNRYLPTASNVPVEHIANDLCIIQPPFCYRSIFIKCSDERFQGQRSLDALFRLLQAKDIKSNIRKSTMTQLNVLLRNWRACEEFSTKEDGYRLIMESLHNALKKGNDTDILLPTVSILMKLLFNDDEFRLEVANTFGVYTLLLRALFLFPHLEQLRQDVSICLFQMLFQNCITSTEDKLVLNANMEPLILPVTYEIEHKVIPTAVTEGLELQQNVEATHFGRDRAKAAQHWRLYMAYRVCQVPSSITLESVSALDIRESLKIKMADLALVRSSDLNEQLSCQFIAAENCSKHEDLQKTVSAIQLFLVVLRNSLSDTVAENLWKLIHKYIRLAPGNEADDKVYKSMLDLCVTCIRFSQPHAINGLSYALETDHHHSFQLLLHDSQISLDKLFLICQCMMQLLSNELSDDSMNWYGKFFMQLSAVAKTHFELRQLQHVRCILCMLRFVSERNLKFSNAQLMSYSQHFIQLSSNLRTSTQTGSEWQRDCLYIICQLQIHLIYQEPKASSKASIPNDVGASYKVLRYFLTLCGHGDSEVRALSWVSLANWITICGSQVAEILPRLDFLPGGLPACCLTTLTDAHEMMLIRELAGRVFILLMPLIGAESSLELLRKHDLLKTAYNSLKAIHDTPWMFKKIVGERHSCEVISCYVAICTKMVAMKPEWCAALCGHSLMSGLSDVMKKLKSQASCSIPLVELCASQICELYSMCYTNNFEFLKMTICRDSVFLQNYLTLINDVLSLECPEYMVIPLLKMFLIFCTDSNSNSFLIEQIKNKPSLFMDFFLFGLHVKLINSPFQRFTLSALSLVFTKAQLAAYDISMLSELEKFELAFSDPDIAKDGKQEFESKKKQSVSQCIYDESSDNSDDNKQRPNHAIQATNAAIIIFHRLDQLFDRYYLSKALNFLELPAVGQVQVCEALGELLKASTWAVKAAGESKLLGKVVHILDDFLNDEKIGNAAVYVKRVGPHKAQSIISNLLVLINMLSQWHSSPNSEIIQTSMAANIAKILIRIWPWLSHSYHLKKVTVQLIMFLTEHSFEMCKQISLLQSGHAQSLLHLMARVADFETTKKEIPNKEPSLNMVPALRVMVNCCCCTEGRLSLSKMNLLDMFDTILPANPCSTHLKVRPPVLIAWLGFWEVFSRYDVGGKACHLQSLINTIRRSPPLSHKRILCLRILRNMCFFNGNRPRLVELADFINLLRDILEQRVQKAPTSEKNGLNSFEEHRLAVLMLWKLFGFGAKYKGMLRGTKLFKLLIGLRVEMSVVFSEEENKYAGVPYANDLAKLLEKLMESMRQ
What is the function of this protein?
Participes in the structural integrity of both centrioles and basal bodies and in centriole cohesion (PubMed:19948479).  Participates in the later stages of centriole assembly through the interaction with Rcd4 leading to the centriole to centrosome conversion (PubMed:32543652).
What are the official names of this protein?
Protein rotatin homolog, Anastral spindle 3.
What is the protein family that this protein belongs to?
Belongs to the rotatin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Associated with the daughter centriole on mitotic entry (PubMed:32543652). Ana3 recruitment to the procentriole in interphase precedes the Rcd4 one (PubMed:32543652). Localizes to the basal bodies (PubMed:19948479).
Protein: RLPA_RICCN
Sequence: MIIVKNHKFKLDLLQNEANKEKFEGNTACSTAAYTLVREDASTGLTYTADISKVGNQISGEPAQRIKIREHRRIPKFDLPNLKVSKVYKLPLEASYAKGLLLLLIFCFGLSGCNTSKRLPYSHKYSYKELSKDDPHNLTYKGHYKVGKNYKIKGKTYKPHNPKSFTETGYASWYGGLKDGFHGKKTANGDRFNRNLLTAAHKTLPLPCLVKVTNKANNKAVILMVNDRGPFKKNRIIDVSQRAAEILAFKNQGITKVKIEYLPNETEKFLKNINLKKPQSKTLAKNSKKSSSNKVTNNNKCSVNCHIKLINLKYKLAVTP
What is the function of this protein?
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
What are the official names of this protein?
Endolytic peptidoglycan transglycosylase RlpA.
What is the protein family that this protein belongs to?
Belongs to the RlpA family.
Protein: PYRG_CHLAA
Sequence: MTKYIFVTGGVVSSVGKGIGVASIGRLLKSRGLSVSVMKLDPYLNVDPGTMSPYQHGEVFVTADGAETDLDLGHYERFIDVNLSRLSNVTTGQIYSAVIAKERRGDYLGGTIQVIPHITNEIKSRIGSLARSSQADVVIVEIGGTVGDIESLPFLEAIRQMRKDVGRDNILYIHVTLLPHISTGELKTKPTQHSVMALRNVGISADIILCRADRPIDDEIREKIAFFADVDVRAVIPVPTVDSIYEVPLVLEDMGLGDYLVERLGLPATPPDLEEWRALVARIRQEKRRVPIALVGKYVELHDAYISVVEALHHAGLEQSIDIDIRWIAAEEVEREGPARLLSGVYGILVPGGFGERGIEGKIAAADYARIHGIPYLGLCLGMQCATIAFARHVLGTHDVNSTEFNPQTAHPVIDLMPDQRDITEKGGTMRLGLYPCDLVPGTRAHAAYGCDRVEERHRHRFEFNNRYRSVLEAAGLVISGISPDKRLVEIIELRDHPWYVASQFHPEFQSRPGKPHPLFRGFVAAAAQTLLAGEARQLPLVESTS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL5_BACFN
Sequence: MSNTASLKKEYAERIAPALKSQFQYSSTMQIPVLKKIVINQGLGMAVADKKIIEVAINEMTAITGQKAVATISRKDIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIETKFDGKGNYTLGIQEQIIFPEINIDSITRILGMNITFVTSAQTDEEGYALLKEFGLPFKNAKKD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RECF_STRGC
Sequence: MWLKSLTLKHFRNYQDAEINFHSGLNIFLGQNAQGKTNILESIYFLALTRSHRTRSDKDFIHFQEKDLKVSGILEKKTGTIPLDIELTAKGRITKINHLKQNRLSDYIGAMNVVLFAPEDLQLIKGSPSLRRKFIDIELGQIKPIYLADLSNYNHVLKQRNSYLKNSQNIDENFLSVLDEQLIEYGCRVVKHRLDFLKKLEIFAQEKHLDISQKKETLTIDYLSSVPLQDIDSIEESFRLSLSKNRKRDLFKQNTGVGPHRDDIAFFINQMDANYGSQGQHRSVVLSLKLAEIKLIENITKESPILLLDDVMSELDNDRQLKLLETISQEIQTFITTTTLEHLKNLPKDIKIFEISNGNIK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_NEIMU
Sequence: MNTVPRYAVFGNPVAHSKSPQIHRQFALQEGVEIEYERICADTGGFAQAVEAFFADGGRGANVTVPFKQEAFALSDEHSERALAAGAVNTLILLENGKIRGDNTDGIGLTDDISKRLGVELSGKTVLLLGAGGAVRGVIPVLKEYRPARIVIANRTHTKAAEMAAHFGIEAIPLDELEGGFDIIINGTSGGLSGQLPAVSPKVFEHCTLAYDMVYGEAAEPFLAFARQSGAKQTADGLGMLVGQAAASYRLWRGFAPDVLPVVQYMREL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS4_SHIB3
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MURA_KOSOT
Sequence: MSEIVVEGGRKLIGEVPISGSKNAALPILAAAVMIDEPVVLDNVPELKDVFTMLTILQRIGKKVSFRDNRVVVEPGNVLMGDVPYELVRMMRASFNVLGPLTMVCGWAKVGKPGGCNIGQRPVDFHIEGLKALGFLIKEEHGDVIAKKPSSFKEELYYKLPFPSVGATEQLMTVAALMSESKTIIENVAREPEIQDLQNFLNKAGAKIKGAGTDRIEIEGVEKLHGIEYHIIPDRIEAGTYLLAGVSTRGRVKVSNVIPEHLEALLKVLDELGVSITCDKNSIEVSVSGELKPIRVSTAPYPGFPTDLQPMLTAVLCTVPGESIIEEKVFENRFGYVDEMNRMSANIKVMNRVAHIVGVEKLSGAQIYAPDIRATAGMLIAALSAEGQTVIKNAAHIFRGYEKLKEKFTTIGAQIEVYPEE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIR5_ARATH
Sequence: MVGQMKSFLFLFVFLVLTKTVISARKPSKSQPKPCKNFVLYYHDIMFGVDDVQNATSAAVTNPPGLGNFKFGKLVIFDDPMTIDKNFQSEPVARAQGFYFYDMKNDYNAWFAYTLVFNSTQHKGTLNIMGADLMMVQSRDLSVVGGTGDFFMSRGIVTFETDTFEGAKYFRVKMDIKLYECY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.  Enantiocomplementary dirigent protein that mediates the laccase-catalyzed enantioselective oxidative phenol coupling of (E)-coniferyl alcohol to (-)-pinoresinol.
What are the official names of this protein?
Dirigent protein 5, AtDIR5.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: HRD1B_ARATH
Sequence: MIQLKVYAGLSTLATLVVIYHAFSSRGQFYPATVYLSTSKINLVVLLNMGLVLMLSLWNLVKIVFLGSLREAEVERLNEQAWRELMEILFAITIFRQDFSVGFISLVVTLLLIKGLHWMAQKRVEYIETTPSVTLLSHVRIVSFMVFLLILDCLLTYSSIQQLIQSRKASMSVFFTFEYMILATTTVSIIVKYAFYVTDMLKEGQWEGKPVYTFYLELVRDLLHLSMYLCFFLMIFMNYGLPLHLIRELYETFRNFKIRVTDYLRYRKITSNMNDRFPDATPEELSSNDATCIICREEMTSAKKLVCGHLFHVHCLRSWLERQNTCPTCRALVVPAENATSTASGNRGPHQESLQQGTGTSSSDGQGSSVSAAASENMSRHEARFQAAASAASIYGRSIVYPSSANTLVWSQGNSLLPQTEVEAQRRFLESQIEVLTNQLRLLEKPTTVDTKGKSVADTA
What is the function of this protein?
Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD).  Targets the misfolded LRR receptor kinase BRI1.  Functions redundantly with HRD3A.
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase HRD1B, AtHrd1B, RING-type E3 ubiquitin transferase HRD1B.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YFDO_ECOLI
Sequence: MTCAQWLWKKIIALYEQAAECDGEVVRPKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELSLRLSPSVSTYTEKREDPYFKASYDNVDYSQIPAGFRG
What are the official names of this protein?
Protein YfdO.
What is the protein family that this protein belongs to?
Belongs to the phage O protein family.
Protein: CRFR2_MOUSE
Sequence: MDAALLLSLLEANCSLALAEELLLDGWGVPPDPEGPYTYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIVNYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIIAWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
What is the function of this protein?
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3.  Has high affinity for UCN.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase.  Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
What are the official names of this protein?
Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, CRF-RB, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPF_VIBC1
Sequence: MIRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHALTDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKEQGYRLGNADVTIMAQAPKMAPHIDAMCAAIAEDLETDISNINVKATTTERLGFTGRKEGIATEAVVLLFKQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MCM7_ARATH
Sequence: MKDHDFDGDKGLAKGFLENFADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYKDESEEFLGRLTENTRRYVSIFSAAVDELLPEPTEAFPDDDHDILMTQRADDGTDNPDVSDPHQQIPSEIKRYYEVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFEPLEPNILRAYISAARRLSPYVPAELEEYIATAYSSIRQEEAKSNTPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMSKISLYADDRQKAGLDAISDTYSIIRDEAARSKKTHVSYANALNWISRKGYSEAQLKECLEEYAALNVWQIDPHTFDIRFI
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (By similarity).  Required for megagametophyte and embryo development.
What are the official names of this protein?
DNA replication licensing factor MCM7, Minichromosome maintenance protein 7, AtMCM7, Protein PROLIFERA.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in the nucleus during G1, S and G2 phases of the cell cycle, and released into the cytoplasmic compartment during mitosis.
Protein: LIPB_BACFR
Sequence: MKTITTDWELIPYSEAWSRQTEWFDALVHAKQNGESYENRIIFCEHPHVYTLGRSGKENNMLLGEEQLKTIGATLYHIDRGGDITYHGPGQLVCYPILNLEEFGLGLKEYVHLLEEAVIRVCASYGVVAGRLEKATGVWLEGDTSRARKICAIGVRSSHYVTMHGLALNVNTDLRYFSYIHPCGFIDKGVTSLQQELGRSIDMAEVKERLGRELLAALLSK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BRAHW
Sequence: MLYQIFYPLRESFFGFNLFRYITFRTAGAVATALILVILFAPGVIEKLKKLHFGQVVRDDGPETHLVKTGTPTMGGIFIVGSILISVLLWAELDNLKIILLTLSLVILSIAGFLDDFLKIKYKNSKGLPGIYKIFFQTFVGIIIGVYLYYFDKSTFLMTFELNQGIGVLEAVKVAQVPSSTIFLPFASTIYIDLKILYIPFATFVVVSMSNAVNLTDGLDGLAIGLLIIMSMALAVLSYVSGNSLIATYLKIPFISDAGEVTVFVGALIGAGLGFLWFNAHPAQVFMGDVGSLSLGGVLGIIALFIKHELLLVIIGAVYVAEALSVVLQVFSYKFFNKKRIFKMAPLHHHFEKSGWKETQVVFRFYIIGIIMALIGIATLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NR0B1_MOUSE
Sequence: MAGEDHPWQGSILYNLLMSAKQKHASQEEREVRLGAQCWGCACGAQPVLGGERLSGGQARSLLYRCCFCGENHPRQGGILYSMLTNARQPSVATQAPRARFGAPCWGCACGSAEPLVGREGLPAGQAPSLLYRCCFCGEEHPRQGSILYSLLTSAQQTHVSREAPEAHRRGEWWQLSYCTQSVGGPEGLQSTQAMAFLYRSYVCGEEQPQQISVASGTPVSADQTPATPQEQPRAPWWDASPGVQRLITLKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPETNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSALFLLRFINSDVVTELFFRPIIGAVSMDDMMLEMLCAKL
What is the function of this protein?
Orphan nuclear receptor.  Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis.  Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions.  May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 0 group B member 1, Nuclear receptor DAX-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus (By similarity).
Protein: RL34_METKA
Sequence: MPAPRYRSRSCRRVYKRTPGGRTVIHFEKKIPNWPKCGACGRRLNGVMRGRNVELKNAPKTQKRPNRPYGGVLCPECARKLIKDKVRYKFWERKREQPWLPVLPDEEPPEPEE
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RLMG_ALIF1
Sequence: MKTELSLLDRSLNLQRYPKRAQELLQAWDAGDEYIIKYVEEELNLEDGKNILILNDNFGALSCWFSDKHNVTMMTDSFVSQRGTLKNLQRNQCNRVQLITSTEEMPQGFDLVLMQIPKNNRMLTWQLQQLRQSMDSSCPIIAVNKAKEIHSSTLELFEDYLGETKTSLAWKKHRLVFSNANVSNPKTIAEAVCWSVDNEDIDLLNYPNVYSGEKLDQGARFMLDHIPSDPELRHIIDLGCGNGVLSVKAGQLNPEARITCVDESFMAVESAHRNLEVNLGKERQFQFIANNCLDGFKKHSSYLVLCNPPFHQGQAITDHIAWQMFCDAKHILCKDGKLLVIGNRHLDYDGKLCRLFGEENVTTVASNSKFVILEAVKAEKSK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_HELP2
Sequence: MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCTGKKGEDKIIVVPPGTQVFVDDTLWLDLVEPKKRVLALKGGKGGLGNAHFKGATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAKPKIANYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASQGKGLGISFLKHIERTKVLAFVLDASRLDLGIKEQYQRLRLELEKFSPALANKPFGVLLNKCDVVENIDKMTRDFCAFLNLEAQKLEAFDLEPYSGFLHPHLTSDFENDPNEKSALFVLPLSAVSALNAHALKFVLLKALQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_STRSV
Sequence: MTVTGIIAEFNPFHNGHKYLLEQASGLKIIAMSGNFVQRGEPAIVDKWTRAQMALEAGADLVLELPFLVSVQAADFFAKGAVDILERLGIDYLMFGTEEVLDYESISKVYGEKAEQMEAYLAGLPDSLSYPQKTQAMWQEFAGLNFSGSTPNHILGLAYAKAVAGRDIKLCSIQRQGAGYHSLSANQEFASATALRQNLDQPDFLKKFTPAHHLLETAPKVIWSDLFSYLRYQIVTCPDLTNFYQVNQELAVRIRVALKSSETIEELVEQVATKRYTKARVRRLLTYILVGARQEELPSGVHILGFSEQGRQHLSQLKGKVELVSRIGKDPWDSLTQQADKVYQLGNPALREQNFGRVPIMKGK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLS1_XENTR
Sequence: MEKESENASCAGLLGQKNEPGSPTQSRSGKHKLSVCSKICFAIGGAPYQITGCALGFFLQIFLLDIAQVPPFYASIILFSGRVWDAITDPLVGFFVSKSSWTRLGRLLPWVVFSTPFAVVSYLLIWFVPGFSGVSMVIWYLVFYCLFQTLVTCFHVPYSALTMFISKEQSDRDSATGYRMTVEVLGTVLGTAIQGQIVGRENTPCVEHIRETHLYNTSVIMEDLNITHDVESLSSTRDAYMIAAGVICAIYVLCAIILTLGVREKRDAYELLSDQPFSFWQGLKLVMSHKPYIKLITGFLFTSLAFMLLEGNFALFLTYTMGFRRDFQNILLVVMLSATLTVPFWQWFLTRFGKKTAVYFGISSVIPFLILVVLMESNLILAYVVAVAAGLSVAAAFLLPWSMLPDVIDDFILKNPDSHGHEPIFFSFYVFFTKFASGVSLGISTLSLDFAGYQTRACSQPEQVNLTLKMLICVAPVILILLGLLLFILYPINEEKRKQNKKALQLIRESNRDSDSDSLELASNV
What is the function of this protein?
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function.  Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain.  Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain.  Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons.  Does not transport docosahexaenoic acid in unesterified fatty acid.
What are the official names of this protein?
Sodium-dependent lysophosphatidylcholine symporter 1, NLS1, Sodium-dependent LPC symporter 1, Major facilitator superfamily domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: QSEB_SALTY
Sequence: MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLELLLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA
What is the function of this protein?
Member of a two-component regulatory system QseB/QseC.  Activates the flagella regulon by activating transcription of flhDC (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein QseB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAA17_ARATH
Sequence: MMGSVELNLRETELCLGLPGGDTVAPVTGNKRGFSETVDLKLNLNNEPANKEGSTTHDVVTFDSKEKSACPKDPAKPPAKAQVVGWPPVRSYRKNVMVSCQKSSGGPEAAAFVKVSMDGAPYLRKIDLRMYKSYDELSNALSNMFSSFTMGKHGGEEGMIDFMNERKLMDLVNSWDYVPSYEDKDGDWMLVGDVPWPMFVDTCKRLRLMKGSDAIGLAPRAMEKCKSRA
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA17, Auxin response 3, Indoleacetic acid-induced protein 17.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.