PharMolix/UniProtQA huggingface dataset:
Protein: DXS_RHOBA
Sequence: MTDQKHPLLAGLQDATPLANWSSTELSNAAVEIRDVLCNLLATRTAHFASNLGVVELCLALHSEFDFRTDRLIWDTGHQVYPHKLVTGRYDRFETIRTAGGLMGYPNPHESVYDLFMTGHAGCSVSTAVGLRSGDILMDQKDRRTVAVIGDGAFPCGVVFEALNNAGELGDDLTIILNDNKMSICHRTGSVAQYLDRLRGNPFYTGLKHEVTKLLDRVPMFGDPAERLLAQMKEGVKAGLLGGMLFEELGIRYIGPIDGHDIPLMQKYLRLCKETPGPVLLHVVTEKGHGYKPAAEDPVFFHTPPAFEDRGGTPVTRGSDGRPPYTTHARDAIGEAMKRDSRVTVITAAMCQGNKLEPVREQFPERFFDVGICESHAVAFAAGQCKTGMRPIVDIYSTFLQRSYDQIFQEVALQDLPVVFMMDRAGLTAPDGPTHHGVYDIGYMRLFPNLVLMAPGYAEELSMMLDKALTLDHPSGIRYPKASALEATHTPAPIEIGKAEWIREGTDGTIVAYGAMLEQAIAAAEQLEGELEIGVVNARFVKPIDAEMVHKTLSDGRFVVTLEEGTRVGGFGSAFLESAVDQRLDTRAVHRLALPDEFVLHGDRSQLLDQSTLSAQKIAEVCREAASEVGSQVGI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PRTC_DICCH
Sequence: MGKNLSLRQDDAQHALSANTSSAYNSVYDFLRYHDRGDGLTVNGKTSYSIDQAAAQITRENVSWNGTNVFGKSANLTFKFLQSVSSIPSGDTGFVKFNAEQIEQAKLSLQSWSDVANLTFTEVTGNKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQGAGSSWYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQSDIIV
What are the official names of this protein?
Serralysin C, Secreted protease C, ProC.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_BART1
Sequence: MAEINSLSELSMATSITEPHENVVPVHVQKLDSQGRAYATGKRKDAVARVWIKPGSGKIIINNKEFDKYFARPVLRMILRQPIVATNRDTQFDIVATVAGGGLSGQAGAIRHGISKALTYYEPELRPILKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LPXD_PROMA
Sequence: MEFSKLIEILNNGDSGLIDHNLSSNPEINSAASLEKAEVNQISFIENASYLFNEINQTKASALILGEKVDITEKLDLKNIAWVTVKNPRIAFAEILEEINPTKVFPESIHPSAVIGNNVKIGKNIYIGANVCIDSNTRIGDNSIIHSGVVIYENVVIGKNNELHANCVIHQYSNLGDNCIINSNAVIGSEGFGFIPTKRGWRKMPQTGKVILGDNVEIGSCSTVDRPAVGDTVIGSGTKIDNLVQVGHGVQIGNHCAMASQVGIAGGAKIGDGVILAGQVGVGNRVKVGSNVIASSKCGIHTDIEPEQVVSGFPAIPNKLWLRCAANFKKLPELAKVIKKLNGSV
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SET9_ASPTN
Sequence: MAPSKARSSPAVERRDRLTLAKLASYDDVATDALVDRAYFWTNTRKNRTKYIPVRGIMDDKVAEILLHHVIVAKDTVKAERELLAISGIKKYMAKLPSDREKEWFRRHLRKYIQMYLPDCPFEVTTTNRYTITEHEAAICARKFIKQGQEIKYLSGTLVPMTREEEQDLDLKRKDFSIVMSSRRKTPSFFLGPARFANHDCDANGRLVTRGSEGMQVVATRDIEIGEEITVSYGEDYFGIDNCECLCLTCERAVRNGWAPQVDSEASSTASTPALNDETKSAHGSTSPQKRKYAPDADSDASASPTPQKRRKFSRQYSKLRTEVSLSGDVTAIEPDPEQNTKIAVETTTDVPKDKPATNGVTENESNARVSENQRATSDREPSSPLGVDESQNSSASTAPTSLFDVGIKLEESTEAFTQETLTTTKAGSVADSHGDGDCRQLTAGIEQEALSELSESLELDDKSGTVVKRRKRRTRRQVVPSVEDESHRVRVPGDYTKTSKLLAQSYDRWVECRTCKTWFLQHNSYLTRRECPRCERHSMLYGFQWPKTDKDGPLDDEERVMDHRTVHRFLYPEEEARISRRDRGVSFGVTPTPELSEPRTETEDSEACDERRNTRASRRRTQSLRMTM
What is the function of this protein?
Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
What are the official names of this protein?
Histone-lysine N-methyltransferase set9, SET domain protein 9.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EFTU_METH1
Sequence: MAKLDFDRSKPHVNIGTIGHVDHGKTTLTAAIATVLAKKGLAEARDYASIDNAPEEKARGITINTSHIEYQTEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVPKIVVFLNKIDMFKDDEREEMVGLVEMDVRSLLSEYGFDGDNAPIIAGSALKALQGDPEYEKGILELMDAVDTYIEEPKRETDKPFLMAVEDVFTITGRGTVATGRVERGVLQLNEEVEIVGLKPTKKTVVTGIEMFRKNLKEAQAGDNAGLLLRGIDRSEVERGQVLAKPKTIVPHTQFEATVYVLKKEEGGRHTPFFHNYKPQFYFRTTDVTGGIEFKPGREMVVPGDNVELTVTLIAPIAIEEGTKFSIREGGRTVGAGSVTKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_GEOKA
Sequence: MEKVYGLIGFPVEHSLSPLMHNDAFARLGIPARYHLFSVEPGQVGAAIAGVRALGIAGVNVTIPHKLAVIPFLDEVDEHARRIGAVNTIINNDGRLVGYNTDGLGYVQALEEEMNITLDGKRILVIGAGGGARGIYFSLLSTAAERIDMANRTVEKAERLVREGDERRSAYFSLAEAETRLAEYDIIINTTSVGMHPRVEVQPLSLERLRPGVIVSDIIYNPLETKWLKEAKARGARVQNGVGMLVYQGALAFEKWTGQWPDVNRMKQLVIEALRR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GS1_NEUCR
Sequence: MAGLFKDIWHAMTSYDRHAGIDSPYRTGRHVPLNRNSGLAGVTTASDSRADINSPYLQGDGRGSTMSFDTAYGGRAISPMPSPANGGPYSPGLVSQRQSVHQDAFDVHSPTGEIPMQNFQNGGPPPPPVASSWEKIDRWAEENYPELFDQLGEGCTVNDLNELEYQLDCTLPQDLRQSLQIHDGQERGGLPTGIIFSSMLLDCEEMVQEWENWKTVNQEFMLDPVLVKRQSQAFAAQASSSKDAPNRNQNWRQELLNKQDSVPPAAIQKAYAHPAWIPLVRDWGGNNLAVDLAPGPKGHWGQIILFGRDYDTKYVVARSWAHFLAMVAEDLSSGRWFVDEDTNELKLREFKATRVEPSYFEILRWRMDQKYGRTANKRKSMAPSMASASGMRSPPTPGSPYQSPTEHNEPRGRSLHRLTGTSPMSSPIRPGYGKPSPLARVAEEAPPTTSLTASNASLEAKAADNLMELNTPRTSGEHSKEDIKVNEDSPAKERTSEDKEKKPETEANGKATESKGKQTTVEDAEDMKDIEI
What is the function of this protein?
Involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.
What are the official names of this protein?
Glucan synthesis regulatory protein, Colonial temperature-sensitive protein 2.
What is the protein family that this protein belongs to?
Belongs to the KNR4/SMI1 family.
Protein: RL22_KLEP7
Sequence: METLAQHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: BIR1A_MOUSE
Sequence: MAEHGESSEDRISEIDYEFLPELSALLGVDAVQLAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKSPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFSCGGCMEKCTEGDDPIQEHNKFFPNCVFLQTPKSSAEVIPALQSHCALPEAMETTSESNHDDPAAVHSTVVGLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLIGCDVSIISKHISQPVQGALTIPEVFSNLSSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRGIRSYLDTSLEIKEFPLSNTVYILKKFFSHNIKRLLEFMVYFGQNEDLQGIHKTPLFVAAVCTDWFENPSDQPFQDMALFKSYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAMRLTELLSSDRQEDQDLGLYYLRQINSPLKALTTYNNFLKYVFSHPSSKAGPTVVSHLLHLVDETELLENTYKNEDYVNHPPGTSRIMKGLKELWLLSPEYYSSFVSEHLLRIALNFAYESNTVAECSPFILQFLRGRTLALKVLNLQYFRDHPESLLLVKSLEVSINGNKVPKVVDYSVMEKSFETLQPPTIDQDYASAFEQMKEHEKNLSENEETIKSIKNIFPLQPPKISSGYWKLSPKPCKIPRLEVGVTNMGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDGKPDVLSVLPGEFPNLLHMEKLSIRTSMESDLSKLVKLIQNSPNLHVFHLKCDFLSNCDSLMAVLASCKKLREIEFSGRCFEAMPFVNILPNFISLKILNLISQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLAFHYILDNDSVIEIARVATSGGFQKLEKLDLSMNHKITEEGYRNFFQALDNLPNLQNLNICRHIPECIQVQATTVKALGQCVSRLPSLTRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKWIVPFSPVVLE
What is the function of this protein?
Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9.  Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9.  Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'.  Acts as a mediator of neuronal survival in pathological conditions.  Prevents motor-neuron apoptosis induced by a variety of signals (By similarity).
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 1a, Neuronal apoptosis inhibitory protein 1.
Protein: GLGB_PROM4
Sequence: MTTSFVSDWMAQEGQKLSDCKHDDPFSVLGIQPFQGKWIARIWMPEAEEVELLINGSLIPLTPPNHPWIFEALLDENPGSNYQVKVHRGGIKHQQYDPWSFRDEWMGEIDTHLFAEGNHHHIWRRMGAHLSEMNGVCGVMFCLWAPNARSVSVIGEVNSWDGRHHPMQKRMGGIWELFIPGLKEGALYKYEIRTQNGHCYEKSDPYGFEHEVRPAQSSKVSRIDNFKWSDQEWITKRDSSNPLDQPISVYEMHLGSWLHAPSDEPFIEPNGNKRTAVPAADLKPGTRLLTYPELKQKLIKYVKERGFTHIELMPISEHPFDGSWGYQATGWYAPTSRYGTPNEFRAFVDACHSEGIGVILDWVPGHFPKDSHGLAFFDGSHLYEHSDPRIGEHKEWGTLIFNYSRNEVRNFLVANLVFWFEQFHIDGIRVDAVASMLYKDYLRPEGQWIPNEDGGNENTEAVKFLQQANHVLFEHFPGALSIAEESTTWPGVTNPTDVGGLGFNLKWNMGWMHDMLDYFEVDPWFRQFHQNNVTFSITYNYTENFMLALSHDEVVHGKSHLLHKMPGDDWRKYANTRALLAYMWTHPGKKTIFMGMEFGQRKEWNVWDDLEWDLLGYQPHQGIQRLVDDLNVLYKSNPALWRDDFNQYGFQWIDCKDNKNSVISFMRRETLNNEWLIVVANFTPESHPNYRVGVPLEGFYEEIFNTDSDKYGGSNTGNMGGKASEKWSIHEYEDSIDLSLPPLSVLVFKYAQKKSPNEN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: IAAB_AROAE
Sequence: MELSEWIDRHAGLEPGKTAIRFPERDLSYAQLAGLVERLASALKASGVAHRSCVAYLGYNSPEMLATLFACARLGALFMPLNWRLAGPEHRQLLADCPPSVLFVEPRFVAQIDAFRDALADVTLVAFDAPPQGWISYEALLERSGDAVPRDPQVGPQTPLLICYTSGTTGKPKGALLSQGALAWNAVNSIDLHELSADDRILTTLPLFHVGGLNNQTTPALSAGATVVLHPKFDADATFDAIEQERITLTVLVPAQLEMMIARPRWQSADLSSLRMITTGSTIVPERLIREVHRRGVPLVQIYGSTETCPIAAYVKPADAQRKAGSAGRAAPHCSLRIVGDDGHDVKPGATGEILVRGPNVMNAYWNDLQASAAVLKDGWFRTGDMGHQDGEGYLWVDGRKKEMIISGGENIYPAEIENLLGESPDIAEVAVVGRLDERWGEVVVAVVVPLEGRTLDAGHVLQLLEGRIARYKLPKEVVFLDELPRTALGKVRKDDVRQLVARKTFMEQT
What is the function of this protein?
Involved in degradation of indoleacetate, the most common member of the auxin class of plant hormones (PubMed:27102732).  Highly specific indoleacetate-CoA ligase which catalyzes the ATP-dependent activation of indoleacetate (IAA) to indoleacetyl-CoA (PubMed:27102732).  Also activates some closely related compounds such as the non-physiological compound (2-naphthyl)acetate and phenylacetate, which seems to be a fortuitous substrate for IaaB (PubMed:27102732).
What are the official names of this protein?
Indoleacetate--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RS20_MYCCT
Sequence: MANIKSQKKRVLTNEKSRLANKAFKSEIKTAIKKALNAKSNDEANKTELVNHAVSLVDKGLKKGIFKDNKAAREKSRLMSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL1_MYCBO
Sequence: MSKTSKAYRAAAAKVDRTNLYTPLQAAKLAKETSSTKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADAAVAAGADVVGSDDLIERIQGGWLEFDAAIAAPDQMAKVGRIARVLGPRGLMPNPKTGTVTADVAKAVADIKGGKINFRVDKQANLHFVIGKASFDEKLLAENYGAAIDEVLRLKPSSSKGRYLKKITVSTTTGPGIPVDPSITRNFAGE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ARLY_ANAD2
Sequence: MRANSKAKPVSRAALAGEADPRLVALSVSIQDDGALYAEDIRGSQAHVSMLAAQGIVPKAAARRIVAALDQVRAEFAAGKIRFDPALEDVHTHVERRLGELVGKDAGYLHAGRSRNDQVALDERLFIVGACDRCDAALERLQRAFLGQARAHERTILPGYTHLQRAQPVSLAHHLLAYVEMFGRDRERFAEVRRRAAISPLGSGALAGTTLPLDREAVAARLGLAGVTHNSLDAVSDRDSAAELLFACALAAVHLSRIGEELVLWTTKEFGFATLSDAFATGSSLMPQKKNPDVGELARGRAGRALGDLVALLAILKGLPLSYNRDLQEDKRPLLGGPEALVLTADAVAGAVETATFHAARMEEALGSGEALATDAAEYLVDRGVPFREAHEAVGKAAAFSAREGRPMARLTAAEWATFHRRFEKDVLRCFDARRSLRRRELPGAPGPRAVRAELRRWEKALGKARR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITBX_DROME
Sequence: MILERNRRCQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQTEGCAWCMQPDFKGQSRCYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCENCKAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGDVKITYFSSCLSNGPEVQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQATSTFKNPMYAGK
What is the function of this protein?
Integrin alpha-PS1/beta-PS is a receptor for laminin (PubMed:7972082).  Integrin alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m (PubMed:7924982, PubMed:7972082, PubMed:9660786).  Contributes to endodermal integrity and adhesion between the midgut epithelium and the surrounding visceral muscle (PubMed:15469969).  Essential for migration of the primordial midgut cells and for maintaining, but not establishing, cell polarity in the midgut epithelium (PubMed:15469969).  The two beta subunits mediate midgut migration by distinct mechanisms: beta-PS requires rhea/talin and Itgbn does not (PubMed:15469969).  Required for rhea/talin correct cellular localization in the midgut (PubMed:15469969).  Required for many embryonic (dorsal closure and somatic muscle attachments) and postembryonic developmental processes (attachment between cell layers of imaginal disks, organization of ommatidial arrays and flight muscle development) (PubMed:8119134, PubMed:7924982, PubMed:7972082, PubMed:10821184).  Involved in the function and/or development of the olfactory system (PubMed:10821184).  In the testes, essential for shv-dependent maintenance of somatic hub cells and their localization to the apical tip (PubMed:27191715).  Plays a role in timely border cell migration during oogenesis (PubMed:19035354).
What are the official names of this protein?
Integrin beta-PS, Position-specific antigen beta subunit, Protein myospheroid, Protein olfactory C.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Lateral cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein. Note=In ovary, localizes to the apical, lateral and basal membranes of follicle cells through oogenesis stage 10A. Apical membrane expression peaks at oogenesis stages 9 and 10A in columnar follicle cells overlying the oocyte but decreases in the most posterior follicle cells. Thereafter, it is down-regulated. Localization to lateral and basal membranes persists during dorsal appendage morphogenesis.
Protein: RIMM_THEAB
Sequence: MINTLRELLSGKVAVAILGKTHGLKGELKLHPFTNFPEIIESLEEIFLYNEKTKQFMVATVENLRLADGYYIIKLNGVENVENARKFVGSKVYINKDELPNLSKDEYYFFEIVGSQVIDESGKVLGVVDEVIQTGSNDVIVVNKNKEDEILIPVIYDYIITLDKENKKIVVKVPEWLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFA_ARATH
Sequence: MTRTVLLRALTKNKFVASNAPRSISISITSLSRCISTLILAEHESGTIKPQTVSTVVAANSLGESSSISLLLAGSGSSLQEAASQAASCHPSVSEVLVADSDKFEYSLAEPWAKLVDFVRQQGDYSHILASSSSFGKNILPRVAALLDVSPITDVVKILGSDQFIRPIYAGNALCTVRYTGAGPCMLTIRSTSFPVTPITANSESKKATVSQIDLSNFEDDSVSKSRYVGRSTQDTERPDLGSARVVITGGRALKSVENFKMIEKLAEKLGGAVGATRAAVDAGYVPNDLQVGQTGKIVAPELYMAFGVSGAIQHLAGIKDSKVIVAVNKDADAPIFQVADYGLVGDLFEVIPELLEKLPEKK
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).  Involved in leucine catabolism and in phytol degradation (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYDC_YEAST
Sequence: MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP
What are the official names of this protein?
Aspartate--tRNA ligase, cytoplasmic, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_CUPPJ
Sequence: MARGNLSSAQMGLDLAPVAASVRFLCGVDEAGRGPLAGPVYAAAVVFDPAKPMLRGLADSKVLTASKREALYDKICERALGWHIAFATVEEIDTLNILHASMLAMQRAVQGLAEKGVTPDLVQVDGNRCPQVPFPVEAIVKGDSLVKAISAASILAKVARDRELLTLHEVYPQYGFDAHSGYPTPQHLAALAQFGATPHHRRSFAPVREAIARGLVAF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_STAAE
Sequence: MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSK_TROWT
Sequence: MSAKKSYLKVWRGLAGAAGSCARVFSKKSLARRDRRDQLPFALFLFGLVGAVFQWFLYGNWLSGIVSEYTVAAFFGGFSIVLPILLIGFSIWLFRNPQKTHDNIRVSIGLFMFSSFSAAFLHFSAGFPYPSSGIRILSTAGGIIGWLVGLPLTTLPSYLAKTVCIIFIVLSVSVISKTPISKIVRVIFRYAKWLFNSDSVKTSPNSSVSSSSEHQELTGRDMPDTAGDNRHDETVTVLSGTSLTGSPVSEYHGESSDYALPSLDILNSYPPAKHDDAENEKVITALSGVLRQFSVNARFSGFSRGPTVTQYELELGEGVKVERIIALTKNISYAVASDKVSILSPIPGKSAIGIEIPNKKRELVALGSVLQSIHPDAHPMTVGLGKDSSGGFVLTNLTTMPHLLVAGATGSGKSSFVNSMITSILLRAHPSQVRLVLIDPKRVELAIYSGVPHLITPIVTDPKKASEVLQWVVKEMERRYDDLASFGFRHIDDFNLAVRAKKIASDSRELTPYPYLLVIVDELADLMLVAAKDVEESIVRITQLARASGIHIVLATQRPSVNVVTGLIKANVPSRLAFAVSSLVDSRVILDRPGAEKLVGQGDGLFLPISAGKPIRIQSSWVTENEILRVVEYVKSQAHPDYYVLEVQNQGNIDSHIGDDMPLLLKATELVINSQLGSTSMLQRKLRVGFAKAGRLMDLMESMGIVGPGQGSKAREVLVTPQDLDSTLARISASVSDSKLD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: PYRD_MYCPA
Sequence: MSGAPPAPRGGGHRWYGVARQLFFLVPAERIHTLVFALLRGVTAVGWPRRLLRRLLAPTDPVLASTVFGVRFPGPLGLAAGFDKDGLGLHAWGALGFGYAEIGTVTAGPQPGNPAPRLFRLPADRALLNRMGFNNLGAGALAVRLARRQPDIPIGVNIGKTKATPPDQAVDDYRASARLLGPLASYLVVNVSSPNTPGLRDLQAVGSLRPILSAVLAETSTPVLVKIAPDLSDSDVDDIADLAVELGLAGIVATNTTVSRDGLRTAGVDQLGAGGISGPPVARRAVEVLRRLYGRVGDRLVLISVGGIETADHAWERITAGASLLQGYTGFVYGGGLWAKQIHDGIAQRLRDGGFASLRDAVGSSARESG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.