PharMolix/UniProtQA huggingface dataset:
Protein: DABA_STAAM
Sequence: MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVASLCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQVGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVPDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSNHWLRLMSVNEEGRFKSWI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1384_THEVO
Sequence: MDSEQINVNLDIGAKAVMLARRAAAAKLNNEKLPEVPDDPIFHEKHGVFTTINTYPDNQLRGCIGFPEPYYELGEGIIKSSIYAATDDPRFDPMEPDELNRVTFELSILTVPQEVTVNPEERPKAITVGKDGIIAVYNGASGLLLPQVATEYRMSAEEFLEALCEKAGLWQGCWKYKKVKISKFQAIVFGEIEPNGKVEQR
What are the official names of this protein?
Protein TV1384.
Protein: CHEB_NITHX
Sequence: MRTAVASPAALDSGRQEPLRVMVVDDSVVIRGLISRWIEAEPDMVVAASLRTGLDAVNQVERANPDVVVLDIEMPELDGISALPQLLAKKRNLIVIMASTLTRRNAEISFKALSLGAADYIPKPESTREIAAADIFKHDLIQKIRHLAAKRRRPAALASAREPEPRPIQATPVPAHSAPVLRPFSTHAPRALLIGSSTGGPQALMTLVAGIGPVIDRYPVLITQHMPPTFTTILAEHLARAAGRPAHEGVDEEIVKPGHIYLATGGRHMRLARKGTGAVIVLDDGPAVNFCKPAVDPLFTSAIDVWQGGILAVILTGMGSDGMRGGQQIVAAGGNVIAQDEASSVVWGMPGAAAQAGICAAVLPLQQIAPKLVRLFAGDHS
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRGV2_HUMAN
Sequence: MQWALAVLLAFLSPASQKSSNLEGRTKSVIRQTGSSAEITCDLAEGSNGYIHWYLHQEGKAPQRLQYYDSYNSKVVLESGVSPGKYYTYASTRNNLRLILRNLIENDFGVYYCATWDG
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor gamma variable 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: NNRE_BORPD
Sequence: MRAESGYSVLQIRQAEQRALAQGRALMPLAGAAAAGFIAARFPVGSVVLALAGPGNNGGDALVAAARLLAAGYTVRVTMPRGPQALPPDAARAYAGWRAQGGAEQSNLPSDPPDVVIDGLFGIGLNRPLDATWQTLVDAVNAWNRPVLALDVPSGVDADSGRVLGRALRARWTLSFIGAARGLCAPGPGREAAGELHLDTLGVALA
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: NS3_LDCPR
Sequence: MTTKLFKQTIIPTNKDVDEKYIYFIERADHKTIKPLHPSFESWQFAGNQHAHQLEQGYSEGHRFITNYNATSRLNSAMTLQIMNKPMITIVKKFTTNTPHQVTTIPEGYSFGVVKEKLCTNEQLLSLLSLTAEPTAESDEEVNDVSRDDEAEKKDVEARMDWSEDIIELPKQQQESVLVVSKPNMIAEEELMPADIEVVAPRVLEPPTLSPAPIVVAVSSESPQVKEIERPLTNAPKEQRTSRKSVTRTTKPSFSSLSSPDIVSASVITPVSKAAARPVEEFLSSVFVSLFEAWFVRMLPLIKLGKPVYIMPGTIKWDKEVQITDTKIRYYNSVSGRLILAEMESITRALQPGELEDRKELVRRTLETVCAGNNIYVLTGNDTFGVLEAE
What are the official names of this protein?
Non-structural protein 3, NS3.
Protein: ALG12_YEAST
Sequence: MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQEMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVLSLLKQIIFDKTPTVFLKELTANSIVKSDVFFTYKRIKQDEKTD
What is the function of this protein?
Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
What are the official names of this protein?
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, Asparagine-linked glycosylation protein 12, Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase, Extracellular mutant protein 39, Mannosyltransferase ALG12.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEPA_STRPN
Sequence: MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPOA_ENT38
Sequence: MVPLTFLRTKASRSLPIMLAALIFAGCGTQAPDQTAAHMQGSAQADSGFYLQQMSQSSNDTKTNWQLLAIRALLNEGKTQQAVDLYNQLPQELNNTQRGEQSLLAAELKIAQKEYPAAKKLLADIDTKALENNQQARYWQAVIAAEQGRPSLPLLRALIAQEPLLSGADKQKNIDTTWQALSSMTPEQSQALVINADENVLQGWLDLQQMWFNNRSDPKMLKAGITDWQTRYPQNPGAKMLPTQLVNVQNFQPASVSKIALLLPLNGQAAVFGRTIQQGFEAAKNGTTAVAGNAVPAQAAQAANVNDVISPSAVETSDLTSAQAPAQGTMQNPVTAPTTPPATTQAPAETAAPAEAQTPVVPQAAPATDAATAQPQTTTPDQQPAAQPQAVAATTANPGAELKIYDTSSQPLDQVLAQVQKDGASIVVGPLLKNNVEELMKSNTSLNVLALNQPEQVQNRANICYFALSPEDEARDAARHIHEQGKQAPLLLTPRSALGDRVATAFAQEWQQLGGNIVLQQKFGSTSELRAGVNGGSGIALTGSPVSASLPQQQGVTIGGLTIPAPPTDAQISGGGKVDAAYIVATPEEIAFIKPMIAMRNGSQSGVTLYASSRSAQGTAGPDFRLEMDGLQYSEIPMLAGSNPALMQQALSSVRNDYSLARLYAMGVDAWALANHFTQMRQVPGFELNGNTGDLTATQDCVINRKLSWLKYQQGQIVPAS
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: Y232_HELPY
Sequence: MKKPYRKISDYAIVGGLSALVMVSIVGCKSNADDKPKEQSSLSQSVQKGAFVILEEQKDKSYKVVEEYPSSRTHIIVRDLQGNERVLSNEEIQKLIKEEEAKIDNGTSKLVQPNNGGSNEGSGFGLGSAILGSAAGAILGSYIGNKLFNNPNYQQNAQRTYKSPQAYQRSQNSFSKSAPSASSMGGASKGQSGFFGSSRPTSSPAVSSGTRGFNS
What are the official names of this protein?
UPF0323 lipoprotein HP_0232.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: IGEB_MOUSE
Sequence: MALQVMFGLEFFLVLEALLFLFTCYQVVKAGRILDEIQDKLSEVKRGERVGTKRKYGTQNKYTGLSKGLEPEEKLRLGRNTWREIRRKRGKREKKKDQLAEVSRKRSLCSSLDGLGKPALSSSEAGEESSSEETDWEEEAAHYQPANWSRKKPKAAGEGQFADWPQGSRLQGPPYAESPPCVVRQQCAERCAERQCAERQCADSFIPREEQRKIQQAFPVFEGAEGGRVHAPVEYLQIKEIAESVRKYGTNANFTLVQLDRLAGMALTPADWQTVVKAALPSMGKYMEWRALWHEAAQAQARANAAALTPEQRDWTFDLLTGQGAYSADQTNYHWGAYAQISSTAIRPGRRSRAGETTGQLTKIIQGPQESFSDFVARMTEAAERIFGESEQAAPLIEQLIYEQATKECRAVHSPKKEQRLTRLAQGLSRAWGKPRLLKTDNGPAYTSQKFQQFCRQMDVTHLTGLPYNPQGQGIVERAHRTLKAYLIKQKRGTFEETVPRAPRVSVSLALFTLNFLNIDAHGHTAAERHVQSQIGPMRWLNGKMSLIINGMARILS
What are the official names of this protein?
IgE-binding protein.
Protein: RF1_IDILO
Sequence: MLNPSIERKLEGLVERYQEVQALLGEPDVISDQNRFRSLSREYSQLEEVVGCFEEYRQNQDDQAAAKDMAEDDDAEMREMAEEELKEARKAEEELENRLQLLLLPKDPNDDRSCYLEIRAGAGGDEASIFAGDLFRMYSRYAEKNGWKVNIVSASDGEHGGYKEIIAHMSGDGVYGRMKFESGGHRVQRVPETESQGRIHTSACTVAVLPEIPEAEAVEINPADLRVDTYRASGAGGQHVNRTDSAIRLTHIPTGVVVECQEERSQHKNRAKAMSVLQARIQRLEDEKRQAEEDSTRRNLVGSGDRSERIRTYNYPQSRVTDHRINLTLYRLDEVLTGDIDLILDAIITEHQADQLAALSEGQQ
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SPICI
Sequence: MSRIGNRELKIPVGLEVTIQPNNVIVKGVKGQLEQTIPSVITVVAKEGVVTTTRANDVKHSKQLHGTINSLIQGMLEGVSKGFKKELEINGVGYRAALVGDKLTLSLGYSHPVEYKIPQGITITLPKPTQIIVEGISKQLVGEVAANIRNYRKPEPYKGKGVKYKNEHIIRKEGKSAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SNG3_MOUSE
Sequence: MEGASFGAGRAGAAFDPVSFARRPQTLLRVVSWVFSIAVFGPIVNEGYVNSDSGPELRCVFNGNAGACRFGVVLGLGAFIACVAFLLLDVRFQQISSVRDRRRAVLLDLGFSGVWSFLWFVGFCFLTNQWQRTTPGPGTAQAGDAARAAIAFSFFSILSWVALTVKALQRFRLGTDMSLFATDQLGTGAAQAYPGYPVGSGVEGTETYQSPPFTETLDTSSKGYQVPAY
What is the function of this protein?
May play a role in regulated exocytosis (PubMed:10383386).  May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal (PubMed:19357284).
What are the official names of this protein?
Synaptogyrin-3.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse. Note=Found at the neuromuscular synapses.
Protein: HLDE_PASMU
Sequence: MFQYSAEFKQAKVLVLGDVMLDRYWFGATNRISPEAPVPVVRVQDNEERAGGAANVAMNIAALNVPVKLLGLTGRDETGLALESLLAKSRIECDFVQLHTHPTITKLRILSRHQQLLRLDFEEDFQNVTSDALLQKLDSALQNYGALVLSDYGKGTLNQVQKMIQLARQANIPVLIDPKGTDFERYRGATLLTPNMSEFEAVVGKCDSEEEIIEKGLKLIEQIDLSALLVTRSEKGMTLLRPNQPAFHLATEAKEVFDVTGAGDTVISVLATGLADGRSFEEACYLANVAAGIVVGKLGTSTVSTVELENAIHGRSNTGFGIMSEAELKRVVAQAKARGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNSDDSVKRLKGETRPINDLQSRMAVLAGLSSVDWLVAFHEDTPQRLIAEVLPDLLVKGGDYKPEDIAGSQEVWASGGDVKVLNFENGCSTSNVISKIQQLKD
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: PDXH_PSEA8
Sequence: MTQSLADMRREYTRDGLSEANAPSDPFSLFRQWFDDAVKTERLPVEPNAMTLATVDADGYPHCRILLLKGLDERGFTFFTNYESAKGRQLAANPRAAMTFFWPALERQVRIEGSVEKVTPEESDAYYQVRPLGSRLGAWASPQSRVIADRAELERLLAETERRFADQPPSCPEHWGGYRLLPQRIEFWQGRPSRLHDRLDYRRQDGGWSRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PDXH_YERPN
Sequence: MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL35_STRPM
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKAGLVSSGDFKRIKAMVTGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GLYA_SERP5
Sequence: MLKREMNIADYDAELWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTILGMNLAHGGHLTHGSPVNLSGKLYNVVPYGIDEKGQIDYEDLAKQAQTHKPKMIIGGFSAFSGIVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHIVTTTTHKTLAGPRGGLILAKGGDEDLYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKIYQQQVAKNAKAMVEVVLERGYKVVSGGTHNHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGVRIGTPAVTRRGFKEADVRELAGWICDVLDNINDEATIERTKKKVLDICARLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O161_CONKN
Sequence: MKLTCVLIISVLFLTASQLITAVYSRDKQQYRAARLRDEMRNLKGARDCGEQGQGCYTRPCCPGLECLGGGTGGGVCQP
What is the function of this protein?
Ion channel inhibitor that inhibits the increase in intracellular calcium upon depolarization in DRG neurons.  In vivo, both intraperitoneal and intracranial injections into mice induce hyperactivity.
What are the official names of this protein?
Conotoxin Kt6.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DJC27_CHICK
Sequence: MEANAPKRKEARKSLRIKVISMGNAEVGKSCIIKRYCEKRFVPKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKESFDALDAWLAEMKQELGPHGNMDNIVFVVCANKIDCTKHRSVDESEGRLWAESRGFLYFETSAQTGEGINEMFQTFYSAIIDLCDNGGKRPPSSMGVGFTKEQADAIRRIRNSKDSWDMLGVKPGATRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK
What is the function of this protein?
GTPase possibly involved in regulation of the MEK/ERK pathway.
What are the official names of this protein?
DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMB_ERWT9
Sequence: MKKMTNLRCIAAQTIEKVVEQGQSLSNVLPAAQKSVGDKDAALLQELCYGVLRTLPQLEWVIGRLMSRPMTGKQRAVHFLIMVGLYQLMFTRIPAHAALAETVEGAVALKRPQLKGLINGVLRQFQRQQDELMQQMNDGDQQYLHPKWLLERLKRAWPAQWKQIVDANNQRPPMWLRVNRQHHSRDAWLTLLEESGKQAFAHPQHGDALRLESPCAVGQLPGFDQGWITVQDVSAQGCVALLAPRDGEQILDLCAAPGGKTTHILEAAPQAKVMAVDVDAQRLARVSENLQRLTMQAEVKQGDGRTPAAWCGDTQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAALQQQILDAVWPHLKPGGTLLYATCSVLPEENHVQIGQFLQRHADATLIETGDLTQPGIQVFPQADGGDGFYYAKLVKQ
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_BIGNA
Sequence: MNPLISASSVVAAGLAIGLAAIGPGIGQGTAAGYAVEGIARQPEAEGKIRGALLLSFAFMESLTIYGLVVALVLLFANPFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: BLAC_BACTU
Sequence: MMILKNKRMLKIGICVGILGLSITSLEAFTGGALQVEAKQKTGQVKHKNQATHKEFSQLEKKFDARVGVYAIDTGTNQTISYRSNERFAFASTYKALAAGVLLQQNSIDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKRIATNLKAFTVGNALPAEKRKILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEASYDNQLIAEATEVIVKALK
What is the function of this protein?
This protein is a beta-lactamase with a substrate specificity for penicillins.
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: URE3_CERS5
Sequence: MNLTPREKDKLLISLAAIVARNRLERGVRLNHPEAVALISDFVVEGAREGRSVADLMQAGAHVIRAEQCMEGVPEMLHSVQVEATFPDGTKLVTVHHPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2BT_BUNCA
Sequence: NLYQFKEMIRYTIP
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini and exhibits indirect hemolytic activity against human erythrocytes.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 T1-2 A chain, svPLA2, Phosphatidylcholine 2-acylhydrolase T1-2 A.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSH_BACVZ
Sequence: MLTYDTWEEPAITFPEDDSYKGALSVLKWAYGHYGDQLVYACSFGIEGIVLIDLISKVKKDAEIVFLDTGLHFKETYETIEKVKERYPGLNIILKKPSLTLEEQAEAHGDKLWEREPNQCCYIRKILPLREALAGHPAWLSGLRRDQGPSRANTNFLNKDDKFQSIKVCPLIHWTWKDIWRYTSKHELDYNILHDQGYPSIGCEPCTSPAFTAEDLRSGRWNGMAKTECGLHE
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDS2_YEAST
Sequence: MVLMEDMQNKDGHNTVENSSGGTDSNNNIQMRRMRKTQLSKKELFEKRKSDVLIAAKSLDTEIQNVKNLKRLSIGSMDLVIDPELEFKVNSRNSYSSDSSKESLQESLHEENIIRSEQKEEQGSEDNDAYEEGDATNVDDSIDITQTEYLHDEETLEKEKIIRNASSSTSSSARVTSRNRRLSGVKTLAHDVVLDVENDHDSKMVDLTQNLLWVPADQHPNVKPENYLELIQDTLQNIQISTNQDIDENKLELGNNHVISNRKRTGSVVRRPSRLKTSYTKFDDEPPLADKPQEGEIQVDKRISSSDIKTIRSVSLKEITEELTKISNNAGLTDSDAVTLARSLSMSGSFTNESLHLNGNHTENDNEFASNMFNETGLTIPERSSLRRSKFNTYKIRLEGSSLPQAVKLNSLMNIQTNDNRRSASSPASYTQVPQEQASLNDFHEIFDHYRRTSTDWSTENEKYVDSTNYYSDEEDLTHASISQESSLLSTDSSNNSVLIKPHNTGSMISEKLDQHVSSSEKSNTNNSEANHGWSWLNSSNGSLNANEQTYQQLTDDEDDEECVDNEKADFVNLSVSRRAKSTKRASERINHSKNRHSPIFQIHSEEAKSVVITPSVVSSSESQPSKPTAPAVVEKKVELPTDTQASTHKKNSLEKRLAKLFKRKQHNGTCKSDVKVIKKSVKKELKKKASHSSLSKFRKSPKKKPQEAEVERPSSPTKTITTEDIDTASVIEPEVRSSNASTLLPDSHTSHSSEFVVETISELDGDDSFDISGGDVNYDVEVHSSISRDTTAGLEEDIGAEREDNTSPTAPQISTLPPRKLTFEDVVKPDYSNAPIKFTDSAFGFPLPMITNSTVIMFDHRLGINVERAIYRLSHLKLSDPGRELRQQVLLSNFMYSYLNLVNHTLYMEQVGTGDIAFNGDSALGMMDKNDSDGTILIPDI
What is the function of this protein?
Acts as a negative regulator of polarized growth via an alternative mechanism to ZDS1.  In heat-stressed cells appears to play a role in localizing BCY1 to the cytoplasm.  Seems to interact with, and down-regulate, CDC42.  Also acts as a suppressor of PKC1.  May act as an integration point for distinct signaling pathways helping to maintain a balance among these different pathways.
What are the official names of this protein?
Protein ZDS2.
What is the protein family that this protein belongs to?
To yeast ZDS1/NRC1/CES1.