PharMolix/UniProtQA huggingface dataset:
Protein: MRS2_NEUCR
Sequence: MPPALRPAAPSRSLLRYLRAQSEGLSFAPTCRAAAERHPALQCRHGCTAGGSTRPPRQPSSSTTTRSLSTATPPKRTQLRAGLVDLEAILPKSLRKQRTTKSLLALPPPAGSLRFSSNQSSDCDSKRPKLREWLFGNGEKKGPPDTRLNDDDIRVALEEESGSIFQRRALTAKAAMDPRLRCTEVDENGNVVMVDGELKKSELIAKYGLLPRDLRKIDSSNLPHILIRPSAILLNLLHLKVLIKHDCVLLFDVYGSKSSYPQSAFMYDLQGKLQQKQSSGANSLPYEFRALEAVLMSVTSELEADFEAVRDPVIRILSELEDDIDREKLRVLLVLSKRVSTFEQKAKLVRDAIEELLEADDDLASMYLTEKTHDLYRGEDDHTEIELLLESYNKICDEVVEEASNLVSSIRNTEEIIRAILDANRNSLMLLDLKFSVGTLGLAMGTFLASWYGMNLENFIEETNWGFAMVTSVSTVASLIVCWYGLVKLRKVQRVKMGDLHNRNAPNHWFRDESTDVLLDPSNRERLRRINSMKSAQQKRSTSKKWF
What is the function of this protein?
High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix.  Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.  It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter mrs2, RNA-splicing protein MRS2.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TILS_CAMJR
Sequence: MQIKDEILALLKKGKNLLAFSYGSDSSALFYLLMQEKIDFDLVMINYKTRKNSDLEELKAKELALKFHKKIFIKHAPKFQSNFEKKARDFRYDFFEKICLEQDYDHLILAHHLNDQFEWFLMQLSRGAGLAEILGMQECEKRQNYTLLRPLLFISKDEISSFLKEKDIFYFHDESNENEKYFRNYIRKNFSNAFVSEFHQGLKRSFSYLDEDRKKLYDFENIKEIQGLLICPKNESLIARAVKMKGLLLSTAQRKELLKGDCVLGGKIALAYKNEQAIVFEYETCQKLPKNFKEECRIAKIPRLLRAYLYNHKIDISSLSF
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHSC_ARATH
Sequence: MAISEASKSSHELPVTTAESSGKKATAKKLTLIPLVFLIYFEVAGGPFGEEPAVQAAGPLLAILGFLIFPFIWSIPEALITAELSTAFPGNGGFVIWAHRAFGSFVGSMMGSLKFLSGVINVASFPVLCVTYLDKLFPVLESGWPRNVCIFASTVVLSFLNYTGLAIVGYAAVVLGLVSLSPFLVMSAMAIPKIKPHRWGSLGTKKKDWNLYFNTLFWNLNFWDNVSTLAGEVDEPQKTFPLALLIAVIFTCVAYLIPLFAVTGAVSVDQSRWENGFHAEAAEMIAGKWLKIWIEIGAVLSSIGLFEAQLSSSAYQLEGMAELGFLPKFFGVRSKWFNTPWVGILISALMSLGLSYMNFTDIISSANFLYTLGMFLEFASFIWLRRKLPQLKRPYRVPLKIPGLVVMCLIPSAFLVLILVFATKIVYLICGVMTIGAIGWYFLINYFRKTKIFEFNEVIDDLDNNVNGEHPKVDDHNS
What is the function of this protein?
Probable cell membrane polyamine/proton symporter involved in the polyamine uptake in cells.
What are the official names of this protein?
Probable polyamine transporter At3g13620.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VHT1_YEAST
Sequence: MTISNKSWRSYFPHLRKLPEDDQYLYSDDTNSSIIAEEELHHSVDKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDEFEYRVNKEYKKSRKWYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGIILYDSNKGEELPEFVKKNMEERDGYYYLKRSS
What is the function of this protein?
Involved in uptake of biotin with the concomitant entry of protons.
What are the official names of this protein?
Vitamin H transporter, H(+)/biotin symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS7_PELPD
Sequence: MTRTATIERNTSETRIRLTLNIDGRGETSIGSGVPFLDHMLNLFARHGLFDLSLEACGDTQIDFHHTVEDIGIVLGEAFKQALADKQGINRYGQVTVPMDETLASAVVDISGRPYLVYNVDLPKAKVGDFDVELAQEFFQAFANHCGINLHINLLYGDNLHHIIEACFKAVGRAMDMATRLDPRVEGVMSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPR1_MOUSE
Sequence: MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDVQKESSGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVIHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIVLNITLVFAAVFKLETDRTVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGILWCLSLLACFFAPISIIPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHKYSYGVRAIVQCIPAWLRFIQCLRRYRDTRRAFPHLVNAGKYSTTFFTVTFAALYSTHEEQNHSDTVVFFYLWVFFCIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITATFKPHVGNIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQEDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
What is the function of this protein?
Plays a role in phosphate homeostasis.  Mediates phosphate export from the cell.  Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity).  Potential receptor for xenotropic and polytropic murine leukemia retroviruses (PubMed:10516044, PubMed:9988277).
What are the official names of this protein?
Xenotropic and polytropic retrovirus receptor 1, Protein SYG1 homolog, Rmc-1.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTPPB_YERPA
Sequence: MPQLVLASTSSYRRALLEKLQLPFITDAPETDETPHAGESTEALVQRLASAKAQALAGRYPQHLIIGSDQVCVIDGKITGKPLQYSTAVKQLQQASGQCVTFYTGLTLLNTANNSINCTCETFDVYFRTLSQAEIDGYLLREQPWNCAGSFKSEGLGITLFERLAGRDPNTLIGLPLIALTQMLIEQGVNPLTVKPVE
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASO_ARATH
Sequence: MAVIVWWLLTVVVVAFHSASAAVVESTWEVEYKYWWPDCKEGIVMAINGQFPGPTIDAVAGDTVIIHVVNKLSTEGVVIHWHGIRQKGTPWADGAAGVTQCPINPGETFTYKFIVDKAGTHFYHGHYGMQRSSGLYGMLIVRSPKERLIYDGEFNLLLSDWWHQSIHAQELALSSRPMRWIGEPQSLLINGRGQFNCSQAAYFNKGGEKDVCTFKENDQCAPQTLRVEPNRVYRLRIASTTALASLNLAVQGHQLVVVEADGNYVAPFTVNDIDVYSGETYSVLLKTNALPSKKYWISVGVRGREPKTPQALTVINYVDATESRPSHPPPVTPIWNDTDRSKSFSKKIFAAKGYPKPPEKSHDQLILLNTQNLYEDYTKWSINNVSLSVPVTPYLGSIRYGLKSAYDLKSPAKKLIMDNYDIMKPPPNPNTTKGSGIYNFAFGIVVDVILQNANVLKGVISEIHPWHIHGHDFWVLGYGEGKFKPGIDEKTFNLKNPPLRNTVVLYPFGWTAIRFVTDNPGVWFFHCHIEPHLHMGMGVVFVEGVDRIGKMEIPDEALGCGLTRKWLMNRGRP
What is the function of this protein?
Ascorbate oxidase involved in a redox system involving ascorbic acid (AsA) (PubMed:15883131, PubMed:27255930).  The oxidation of AsA represses responses to high salinity and oxidative stress conditions such as vegetative growth and seed production reductions (PubMed:15883131).  Negative regulator of defense responses toward incompatible Turnip mosaic virus (TuMV strain UK1) by preventing jasmonic acid (JA)- dependent accumulation of ascorbic acid (AsA, AS) and dehydroascobic acid (DHA) (PubMed:27255930).
What are the official names of this protein?
L-ascorbate oxidase, AAO, AO, ASO, Ascorbase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPH_SALDC
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRQRGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPEDVWTLNVKNEGKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVLVVGSKNSSNSNRLAELAQRMGRTAFLIDDAADIQEAWVKEAACVGVTAGASAPDILVQNVIARLREFGGGEAVTLEGREENIVFEVPKELRVDVREVE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DHE1_ARATH
Sequence: MNALAATNRNFKLAARLLGLDSKLEKSLLIPFREIKVECTIPKDDGTLASFVGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVAKIPYGGAKGGIGCDPSKLSISELERLTRVFTQKIHDLIGIHTDVPAPDMGTGPQTMAWILDEYSKFHGYSPAVVTGKPIDLGGSLGRDAATGRGVMFGTEALLNEHGKTISGQRFVIQGFGNVGSWAAKLISEKGGKIVAVSDITGAIKNKDGIDIPALLKHTKEHRGVKGFDGADPIDPNSILVEDCDILVPAALGGVINRENANEIKAKFIIEAANHPTDPDADEILSKKGVVILPDIYANSGGVTVSYFEWVQNIQGFMWEEEKVNDELKTYMTRSFKDLKEMCKTHSCDLRMGAFTLGVNRVAQATILRGWGA
What are the official names of this protein?
Glutamate dehydrogenase 1, GDH 1.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: AACC4_SALSP
Sequence: MQYEWRKAELIGQLLNLGVTPGGVLLVHSSFRSVRPLEDGPLGLIEALRAALGPGGTLVMPSWSGLDDEPFDPATSPVTPDLGVVSDTFWRLPNVKRSAHPFAFAAAGPQAEQIISDPLPLPPHSPASPVARVHELDGQVLLLGVGHDANTTLHLAELMAKVPYGVPRHCTILQDGKLVRVDYLENDHCCERFALADRWLKEKSLQKEGPVGHAFARLIRSRDIVATALGQLGRDPLIFLHPPEGGMRRMRCRSPVDWLSS
What is the function of this protein?
Resistance to antibiotics containing the 2-deoxy-streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin.
What are the official names of this protein?
Aminoglycoside N(3)-acetyltransferase IV, ACC(3)-IV, Aminocyclitol 3-N-acetyltransferase type IV.
What is the protein family that this protein belongs to?
Belongs to the antibiotic N-acetyltransferase family.
Protein: RL31_HELAH
Sequence: MKKGIHPEYIPCKVTCVTSGKEIEVLSTKPEMRIDISSFCHPFYTGSDKIADTAGRVEKFKQRYNLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: URED_ACET2
Sequence: MKNKFGKESRLYIRAKVSDGKTCLQDSYFTAPFKIAKPFYEGHGGFMNLMVMSASAGVMEGDNYRIEVELDKGARVKLEGQSYQKIHRMKNGTAVQYNSFTLADGAFLDYAPNPTIPFADSAFYSNTECRMEEGSAFIYSEILAAGRVKSGEIFRFREYHSGIKIYYGGELIFLENQFLFPKVQNLEGIGFFEGFTHQASMGFFCKQISDELIDKLCVMLTAMEDVQFGLSKTKKYGFVVRILGNSSDRLESILKLIRNILY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHHA_CHEDE
Sequence: QVFDQACKGVYDRAIFKKLDRVCDDCYNLYRKPYVAVSCRGNCYNNLVFRQCLEELFLGNGFNEYISGVQTV
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormone A, CHHA.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_ACTSZ
Sequence: MIDPNLLRNNLEETAQKLKEKRNFILDVKQLRKLEEQRKALQVKTETLQAERNLRSKAIGAAKARGENIESLLNEVDHLGIELAQAKALFDDVSAELNTILLTIPNIPADEVPQGKDDTENQEVARWGTPRTFDFEVKDHVTLGENIDGLDFSAGVKLSGARFAVMKGRIAKLHRALAQFMLDLHTEKHGYLETYVPYLVNHTTLYGTGQLPKFGEDLFHTKALEGEQPYALIPTAEVPVTNLVRDEILSVENLPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVEPEKSMEALEELTGHAEEVLRLLNLPYRKVLLCSGDMGFGACKTYDLEVWLPAQNTYREISSCSNMWDFQARRMQARCRAKGDKKTRLVHTLNGSGLAVGRTLVAVLENYQNADGSITVPEVLRPYMDNVDTIGR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YM87_YEAST
Sequence: MNPSVPKVMKRENNTHLLVSKEMNDTSLQLPSTTRSLSPKESNSNEDFNVDGNETTLQRISKDYLKPNIGLVLLTVSYFFNSAMVVSTKVLENDPDDIANDRQIKPLQILLVRMVITYIGTLIYMYINKSTISDVPFGKPEVRKWLVLRGCTGFFGVFGMYYSLMYLTISDAVLITFLAPSLTIFLSWVILRERFTKVEALGSLISLLGVVLIVRPSFLFGTPELTDSSSQIVESSDPKSRLIATLVGLWGVLGMSCVYIIIRYIGKRAHAIMSVSYFSLITAIVSFIGINTIPSMKFQIPHSKKQWILFGNLGVSGFIFQLLLTMGIQRERAGRGSLMTYTQLLYAVFWDVALYKHWPNIWSWIGMIIIISATLWVIRIRAANNETTAKDLTPIIDDEENSIPLTEFDLSDSK
What are the official names of this protein?
Uncharacterized membrane protein YMR253C.
What is the protein family that this protein belongs to?
To yeast YPL264c.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Localizes to cytoplasmic punctate structures.
Protein: LUXS_LISMC
Sequence: MAEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLEHLMAELARNHTDKLVDISPMGCQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACNEVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TARP_HUMAN
Sequence: MQMFPPSPLFFFLQLLKQSSRRLEHTFVFLRNFSLMLLRYIGKKRRATRFWDPRRGTP
What are the official names of this protein?
T-cell receptor gamma alternate reading frame protein, TARP.
Protein: PUM12_ARATH
Sequence: MDQRRGNELDEFEKLLGEIPKVTSGNDYNHFPICLSSSRSQSIKKVDQYLPDDRAFTTSFSEANLHFGIPNHTPESPHPLFINPSYHSPSNSPCVYDKFDSRKLDPVMFRKLQQVGYLPNLSSGISPAQRQHYLPHSQPLSHYQSPMTWRDIEEENFQRLKLQEEQYLSINPHFLHLQSMDTVPRQDHFDYRRAEQSNRNLFWNGEDGNESVRKMCYPEKILMRSQMDLNTAKVIKYGAGDESQNGRLWLQNQLNEDLTMSLNNLSLQPQKYNSIAEARGKIYYLAKDQHGCRFLQRIFSEKDGNDIEMIFNEIIDYISELMMDPFGNYLVQKLLEVCNEDQRMQIVHSITRKPGLLIKISCDMHGTRAVQKIVETAKREEEISIIISALKHGIVHLIKNVNGNHVVQRCLQYLLPYCGKFLFEAAITHCVELATDRHGCCVLQKCLGYSEGEQKQHLVSEIASNALLLSQDPFGNYVLQYVFELQLQWATFEILEQLEGNYTELSMQKCSSNVVEKCLKLADDKHRARIIRELINYGRLDQVMLDPYGNYVIQAALKQSKGNVHALLVDAIKLNISSLRTNPYGKKVLSALSSKK
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Pumilio homolog 12, APUM-12, AtPUM12.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PTMCB_CLOAB
Sequence: METYKDSTQVSKSSLKKKIQGFGGFLSGMVMPNIGAFIAWGLITALFIKTGWLPNDNLSKLVDPMIHYMLPMLIGYQGGKLVYDTRGGVVGAIATMGMIVGASIPMFLGGMIIGPLGGYVIKKFDKAIENKIPTGFEMLVNNFSAGILGAALAIISYVAVGPVVAGASTGLGSIALAITNQGLLPLIAVVVEPAKILFLNNAINHGVFSPLGIEQVQHLGKSVFFLLEADPGPGLGILLAYSLYGKGSAKNSAPGAVIIHFLGGIHEIYFPYVLMKPFLLLAVIAGGICADLTFVLLKAGLVAAASPGSIIAILAMSPKGGQLPVLAGVAVGAIVSFVVASIILKGSKEKSKDNFEEAQNKMKEMKKESKNQTTANSENVKNNDELVSSDIKLIVFACDAGMGSSAMGESILKKELKNANIDGIKVQHYSVDSIPKEADVVFVQENLSERARKSAPDANIVTIKNFLDRSTYEGFMKKIKK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH_CITK8
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYSLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTQEDVGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3787_BACMK
Sequence: MEYQYPLDYNWSNEEMVAVVKFYEAIEKVYEKGVLREDLMELYRRFKEIVPSKAAEKKIDKEFQEVSGYSIYRTIQRAKEVAEKKIVKM
What are the official names of this protein?
UPF0223 protein BcerKBAB4_3787.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: THIE_ECO24
Sequence: MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TX4_LOXIN
Sequence: ARGDAEKWESLISEERACKGEGVKGCYDKPDDWCCKKTPCKCPAWSHERECRCTQPCARRCRGKRALMLDPETHRLLFSED
What is the function of this protein?
Toxin active against insects (S. frugiperda larvae).  May act on sodium (Nav) or calcium (Cav) channels.
What are the official names of this protein?
U1-sicaritoxin-Li1c, U1-SCRTX-Li1c, LiTx4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 28 (Litx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMK_ECOUT
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: BY55_HUMAN
Sequence: MLLEPGRGCCALAILLAIVDIQSGGCINITSSASQEGTRLNLICTVWHKKEEAEGFVVFLCKDRSGDCSPETSLKQLRLKRDPGIDGVGEISSQLMFTISQVTPLHSGTYQCCARSQKSGIRLQGHFFSILFTETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQAL
What is the function of this protein?
The soluble GPI-cleaved form, usually released by activated lymphocytes, might play an immune regulatory role by limiting lymphocyte effector functions.
What are the official names of this protein?
CD160 antigen, Natural killer cell receptor BY55.
What are the subcellular locations of this protein?
[CD160 antigen]: Cell membrane; Lipid-anchor, GPI-anchor. SUBCELLULAR LOCATION: [CD160 antigen, soluble form]: Secreted. Note=Released from the cell membrane by GPI cleavage.
Protein: PIT2_USTMA
Sequence: MLFRSAFVLLIVAFASACLVQHVQAKQIPVRRSLSTDASMSSAAGKLNRRWWFGFTGSLGKEPDNGQVQIKIIPDALIIKNPPANKDDLNKLIENLKRKHPRFKTVVMPTDPNGDVVIWE
What is the function of this protein?
Secreted effector required for virulence (PubMed:21692877, PubMed:23459172).  Functions as an inhibitor of a set of apoplastic maize papain-like cysteine proteases (PLCPs) including CP1A, CP1B, XCP2 and CP2, whose activity is directly linked with salicylic-acid-associated plant defenses (PubMed:23459172).  Acts as a substrate mimicking molecule for apoplastic PLCPs and its processing releases the embedded inhibitor peptide PID14, which in turn blocks PLCPs to modulate host immunity (PubMed:30952847).
What are the official names of this protein?
Secreted effector PIT2, Proteins important for tumors 2.
What are the subcellular locations of this protein?
Secreted. Note=Secreted to the biotrophic interface.
Protein: CRK26_ARATH
Sequence: MLSLLLPLISLLFQIQCFTVKSQPVPLNQICSNVTGNFTVNTPYAVNLDRLISSLSSLRRNVNGFYNISVGDSDEKVNSISQCRGDVKLEVCINCIAMAGKRLVTLCPVQKEAIIWYDKCTFRYSNRTIFNRLEISPHTSITGTRNFTGDRDSWEKSLRGLLEGLKNRASVIGRSKKNFVVGETSGPSFQTLFGLVQCTPDISEEDCSYCLSQGIAKIPSCCDMKMGSYVMSPSCMLAYAPWRFYDPVDTDDPSSVPATPSRPPKNETRSVTQGDKNRGVPKALIFASASVAIVVLFIVLLVVFLKLRRKENIRNSENKHENENISTDSMKFDFSVLQDATSHFSLENKLGEGGFGAVYKGVLSDGQKIAVKRLSKNAQQGETEFKNEFLLVAKLQHRNLVKLLGYSIEGTERLLVYEFLPHTSLDKFIFDPIQGNELEWEIRYKIIGGVARGLLYLHQDSRLRIIHRDLKASNILLDEEMTPKIADFGMARLFDIDHTTQRYTNRIVGTFGYMAPEYVMHGQFSFKTDVYSFGVLVLEIISGKKNSGFSSEDSMGDLISFAWRNWKEGVALNLVDKILMTMSSYSSNMIMRCINIGLLCVQEKVAERPSMASVVLMLDGHTIALSEPSKPAFFSHSNAVSDSSSSLGHNAKTSNYNSNTELYPR
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 26, Cysteine-rich RLK26.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GSA_LIMRJ
Sequence: MSKLDTTKSKIAFKEAQKYMPGGVNSPVRAFKNVGGDPLFIDHGKDEYIYDIDGNKYIDYVLSWGPLILGHADDHVVAELDKAVAKGTSYGAPTLQETELAKIVNKIMPSIEMIRMVSSGTEATMSAIRLARGYTHRKKIVKFVGNYHGHSDSLLVDAGSGLATFGINTSPGVPDDLAYDTLTVAYNDVAGVKKLFAEHGDEIACAIVEPVAGNMGVIPGTQEFLQTLRNVTNEHGALLIFDEVMSGFRAAYHGVQSLVNITPDLTTLGKVIGGGLPVGAFGGRREIMENITPAGDIYHAGTLSGNPLAMTGGISTLEQLTPDDYVEMDKKVTALTEGIKHAADQYGVPMTVHHVGTMWSYFYNSDPINNFDDVKACDQKLFEKCFWELLAHGVYVAPSQFETNFISTKHTDEDIEKTIAAFDAAFNAATK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KISHA_TAEGU
Sequence: MSAIFNFQSLLTVILLLICTCAYIRSLAPSLLDKNKSGLLGIFWKCARIGERKSPYVAVCCVVMAFSILFMQ
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish-A, Transmembrane protein 167A.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.