PharMolix/UniProtQA huggingface dataset:
Protein: SH2D5_PONAB
Sequence: MQKAGAGGRRASDCGLAPHRPRCITKFAQYVGLLPCGRPGHPGERVAGAAAAVGAEDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYSTWCPADCQFAFVARNPRSPASKFFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQDCGPLGRPPRTLRPLSHAKSEAELQGLG
What is the function of this protein?
May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.
What are the official names of this protein?
SH2 domain-containing protein 5.
What are the subcellular locations of this protein?
Postsynaptic density.
Protein: CREL2_CRIGR
Sequence: MHLPPAAAVGLLLLLLPPPARVASRKPTMCQRCRALVDKFNQGMANTARKNFGGGNTAWEEKSLSKYEFSEIRLLEIMEGLCDSNDFECNQLLEQHEEQLEAWWQTLKKECPNLFEWFCVHTLKACCLPGTYGPDCQECQGGSQRPCSGNGHCDGDGSRQGDGSCQCHVGYKGPLCIDCMDGYFSLLRNETHSFCTACDESCKTCSGPTNKGCVECEVGWTRVEDACVDVDECAAETPPCSNVQYCENVNGSYTCEECDSTCVGCTGKGPANCKECISGYSKQKGECADIDECSLETKVCKKENENCYNTPGSFVCVCPEGFEEDRRCLCTDSRRRSGRGKSHTATLP
What is the function of this protein?
Protein disulfide isomerase (By similarity).  Might play a role in the unfolded protein response (By similarity).  May regulate transport of alpha4-beta2 neuronal acetylcholine receptor (By similarity).
What are the official names of this protein?
Protein disulfide isomerase CRELD2, Cysteine-rich with EGF-like domain protein 2, Protein HT.
What is the protein family that this protein belongs to?
Belongs to the CRELD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: SUCC_YERPP
Sequence: MNLHEYQAKQLFARYGMPAPTGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKLVNSKEDIRAFAEQWLGKKLVTYQTDANGQPVHQILVEAATDIDKELYLGAVIDRSSRRVVFMASTEGGVEIEKVAEETPELIHKIALDPLTGPQPYQGRELAFKLGLTGKQVGQFTKIFMGLATLFLERDLAMVEINPLVVTKQGDLICLDGKLGADGNALFRQPELREMRDPSQEDAREAHAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVFVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAATSLTDAAQQVVAAVGAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LRC33_RAT
Sequence: MEFLPLWLCLGFHFLIVEWRSGRGTATAASQGGCKVVDRVADCRSLNLASVPSGLPAHSRMLVLDANPLRVLWNHSLQAYPRLEDLSLHSCHLDRISHWAFHEQGHLQNLVLADNRLSENYKESATALHTLLRLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSVFEGLERLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEAAFELEILDLSHNQLLFFPLLPQCGKLHTLLLQDNSMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVSLWEEFSSSDLSALRFLDMSQNQLRHLPDGFLKKTPSLSHLNLNQNCLTKLHIREHEPPGALTELDLSRNQLAELHLAPGLTGSLKNLRVFNLSSNQLLGVPTGLFHSASSITTLDMSHNQISLCPQTVPLDWEEPSSCVDFRNMASLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGILNGSVSPLSAVAPTLQVLSLRNVGLGSGAAEMDFSGFGNLRELDLSGNSLTSFPKFKGSSALQTLDLRRNSLTALPQRVVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQHFKTIADLSMVTCNLSSKIIRVVELPEGIPQDCKWGQVDTGLFYLVLILPSCLTLLVASTVIFLTFKKPLLQVIKSRCHWSSIY
What is the function of this protein?
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system.  Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1.  TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighboring microglia, suggesting the existence of localized and selective activation of TGF-beta-1 by LRRC33/NRROS.  Indirectly plays a role in Toll-like receptor (TLR) signaling: ability to inhibit TLR-mediated NF-kappa-B activation and cytokine production is probably a consequence of its role in TGF-beta-1 signaling.
What are the official names of this protein?
Transforming growth factor beta activator LRRC33, Leucine-rich repeat-containing protein 33^, Negative regulator of reactive oxygen species.
What is the protein family that this protein belongs to?
Belongs to the LRRC32/LRRC33 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: Y3926_AZOC5
Sequence: MNVLSMFGRNATRETSSPAATAGRYADEGDWEGDDHQPATAEGSLAAFGLAKSYGGRKVVRDVSLDVRRGEAVGLLGPNGAGKTTVFYMITGLVKADQGRIELDGHDVTPMPMYRRARLGIGYLPQEASIFRGLSVEDNIGAVLEITEPNRKRRAEELDALLEEFKITHVRKSPSIALSGGERRRVEIARALASRPAFMLLDEPFAGIDPIAVGDIQALVRHLTTRGIGVLITDHNVRETLGLIDRAYIIHSGTVLMEGDPESIVASPDVRRLYLGEEFRL
What are the official names of this protein?
Probable ABC transporter ATP-binding protein AZC_3926, ORF1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: GLGC_MAGSA
Sequence: MFDPTERGTAIDIEVNDRLRKTLALILAGGRGSRLMDLTDWHAKPAIPFAGKFRIVDFTLSNCINSGIRRIGVLTQYKAHSLLQHIQRGWGFLRGEFNEFIELLPAQQRTQGENWYKGTADAVFQNLDIIHAHRPEHVLVLAGDHVYKMHYGKMLAHHLAAGADVTVACIEVPLETAKGFGVMAVDEDDRVIRFDEKPDHPQPMPGHPDQALASMGIYIFNAQLLFDLLQKDSINPETSHDFGKDIIPSLVKSHRVIAHHFQDSCVMHEGAREHYWRDVGTIDAYWEANIDLTTVTPALNLYDESWPIWTDQPQSPPAKFVFDSEHRRGMAVDSLVAGGCIVSGAVVRRSMLFSNVRVNSFCVVEDAVILPNVDIGRHARLKRCIVDQGVVVPPGLVVGEDPVLDAKRFHRTEKGITLVTAEKLKLLGA
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: HIS3_METM5
Sequence: MDLDIKEIVKNMDLKFRNIEGKKLLLAISTDKSGKVLMTAFMSEESLEKSIETGFMHYYSTSRDKLWRKGEESGNVQKIINVFRDCDGDALLFTVEQTGWACHEGYMSCFHNKIDLSTGKSTVVGNKLD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPD_VIBC3
Sequence: MTTHQFEHPLNEKTRIYLRVEALLNQMERASTFSDGIQHQLFFRSLFDMLEIFEQIQLKSELAKDMEKQRLTYRSWLHVEGVDQEMLNSLLTEVDEVHRDLMSAERFGQSLKEDRFLSAIRQRFNLPGGSCCFDLPALHYWLHLPLDRKMRDAQQWMQTVTPLSNALKLWLKLTRETGHYRSRMASNGFYQSDAEDANILRLAIPLEYGVYPMISGHKNRFAIKFIDFHSGQACTQDIAFDLAVCC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RL4_SHESW
Sequence: MELVLKDAQSALEVSETTFGRDFNEALVHQVVVAYAANARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKGPIWRGGGVTFAAKTQDHSQKVNKKMYRGALKSILSELVRQERLVVVESFGVEAPKTKELKAKLKAMNLEDVLIVTAEVDENLFLAARNLYKVDVRDVAGLDPVSLIAFNTVLVTADAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL31B_STRPG
Sequence: MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: TPPC2_CANLF
Sequence: MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFAMNPFYEPNSPIRSSAFDRKVQFLGKKHLLS
What is the function of this protein?
Prevents ENO1-mediated transcriptional repression and antagonizes ENO1-mediated cell death.  May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity).
What are the official names of this protein?
Trafficking protein particle complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasm. Note=Localized in perinuclear granular structures.
Protein: NHAA_STRAT
Sequence: MAAPRTPNTARKVLGRLSLPERTFVADALRTETVGGVLLLVATVTALVWANIPALQHSYEAVSHFHFGPSALGLNLSVAHWAADGLLAVFFFVAGIELKRELVAGDLRDPRAAVLPVVAALCGMAVPALVYTLTNLTGHGSTQGWAVPTATDIAFALAVLAVIGTSLPSALRAFLLTLAVVDDLFAILIIAIFFTERINFAALGGAVAGLAVFWLLLRKGVRGWYVYVPLAVVVWALMYNSGVHATIAGVAMGLMLRCTTREGEEHSPGEHIEHLVRPLSAGLAVPLFALFSAGVVVSGGALGDVFTEPETLGVVLGLVVGKTLGIFGSTWLTARFTHAELSEDLEWADIFAVASLAGIGFTVSLLIGELAFAGDTLLTDEVKAAVLTGSLIAALCATVLLKIRNARYRGLCEDEERDEDRDGIPDVYEQDDPAYHLRMADIFERKAAEHRRIAAEKAAAARHGGAEVPGGAGEEDGRPA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL32_ECOBW
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RBSA_BACAN
Sequence: MRIEMKNISKAFNGNPVLKNAQFMIETGEVHALMGENGAGKSTLMKILTGVYKRDGGTITIDGQERTFKNAKEAEEYGIAFIHQELNILPNLTVAENMFLGKELMYGKTGILRTRQMNAIAQQQLAELGLHVKGAMLAGELSVGQQQIIEIAKALMTNASVIIMDEPTAALTDREIETLFTVINKLRKEGVSFVYISHRMEEIFSICDAITILRDGEYVGKRSIPETSFDEVVSMMVGRSIGERYPERNSQIGDVIFEMRNGTKKGKFENVSFQVRKGEILGVAGLMGAGRTDIMKAIFGYEPLDSGQIFINGQEVKIDSPIDAIRQRIAFITEDRKSEGLVLDFSIRENLALPNLESLSKGSVLSNELEQQFTADMMKLLNVKASSGEQAVKSLSGGNQQKVVIAKWLGIHPQLLILDEPTRGVDVGAKKEIYSIMNKLTEEGDAVIMVSSELPEVLGMSDRVLVIHEGKVGGILEKDEASQESIMALATGGE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEG_PSEAE
Sequence: MTPQPLADNLSPPDPARLAQSIKDWGRELGFQQVGISDVELGEHEAHLQRWLEAGYHGEMDYMAAHGSKRSRPAELVPGTLRVISLRMDYLPGDTRMAQVLATPEKAYVSRYALGRDYHKLIRKRLQQLAERIQAEVGPFGFRAFVDSAPVLEKAIAEQAGLGWIGKNTLVLNRKAGSYFFLGELFVDMPLPVDPAMDSEHCGRCSACLDICPTAAFVGPYRLDARRCISYLTIEYKGAIPLELRPLIGNRVFGCDDCQIVCPWNRFARPTGQGDFQPRHSLDNAELAELFLWSEEEFLGRTEGSPLRRAGYERWLRNLAVGLGNAPSTIPVLEALKARRGFPSELVREHVEWALRRHGET
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VU8_HHV6Z
Sequence: MRRKACESKRGLKFNKVCHTTLFFPISCHVTASRIEVLYFRYFIVSLLVLFGVFKMDLEAKEVSGEIPNENALAELCRFCESADLSRIENFVGTYKNWCLSIIWPRNCWLRFTLRKDVAGYTEKMFEDMNDHYQGFVEKLCLLGTIQIPYRDVPILIGRSKRIFLHDLETDTLHFVCDNFEQFVRYGVLGTNIITCAEPVYRHGLYDGPRFESLENLRNNDVLRSPCTLNIHLKLNRKGVLGIKAMRKHYIAMLREFDELARCASLDDVERFVSLNVGRDLRLDMPVFKSLTLGTRDSVWIGTCRLANLEEQEDLVEKVVVLGYLNDHDYESKCTRPILCIGKSGKIYYYDWIDNVLVKLGDCLLTFLRVGFARLFADCGYEKIGKISMRFGRMSTLGMSETYQSCMSLSK
What are the official names of this protein?
Protein U8.
Protein: MURD_GEOMG
Sequence: MEISGKNILVVGLARTGVAVARFLARNGARVTVTDLRDESALAGPLRELAGLSVRYVLDRHDEADFAAADVVVVSPGVPQESPYLQAARRAGREVITEIELASRFVTVPMVAITGTNGKTTTTTLTGEIFSACGFRTFVGGNIGNPLIELVEGGETVERVVVEISSFQLEWISSFRPRVAVLLNITEDHLDRYATFQEYIDAKVRIFENQESTDYAVLNVDDPIVAGIAGRVAATVFPMSQQRELAEGVFHRDGVITFRHQGREERFPTARFRITGVHNIENIMASLAATLLLGCDAKQALAAVEGFGGLPHRMELVRELAGVRYYEDSKATNVGSVEKALASFNDITLIAGGKDKGGSYAPLAPLVTERVRHMVLIGEAKERMARELGSLTDTRMATTLEEAVELAASLTEPGGVVLFSPACSSFDMFRDYEERAQRFRAAVNALGTGERP
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_RALSO
Sequence: MSASETPSASASRGLSYRDAGVDIEAGDALVDRIKPFAKRTLREGVLGGIGGFGALFEISKKYQEPVLVSGTDGVGTKLKLAFALNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVDTAATVIKGIAQGCELAGCALIGGETAEMPSMYPAGEYDLAGFAVGAVEKRKIIDGTTIACGDVVLGLASSGAHSNGYSLVRKIIEVSRPDLNADFHGQRLQDAIMAPTRIYVKPLLALIDKLPVKGMAHITGGGLVENVPRVLPEGVTAVLHQDAWTLPPLFQWLQKAGNVADDEMHRVFNCGIGMIVIVSAADAPAAIAHLKDAGETVYQIGEIRARQPGEAQTIVI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_RUEST
Sequence: MGIQAAEISAILKDQIKNFGQEAEVAEIGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIMGMALNLESDNVGVVIFGSDRDIKEGDTVKRTNSIVDVPAGPELLGRVVDGLGNPLDGKGPIEAKERKVADVKAPGIIPRKSVHEPMATGLKSVDAMIPVGRGQRELIIGDRQTGKTAIALDTILNQKSYNDAAGDDDSKKLYCVYVAVGQKRSTVAQLVKKLEESGAMEYSIVVAATASDPAPMQFLAPYAATAMAEYFRDSGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEDFGAGSLTALPIIETQGGDVSAFIPTNVISITDGQIFLETELFYQGIRPAVNTGLSVSRVGSSAQTDAMSSVAGPVKLSLAQYREMAAFAQFGSDLDAATQQLLARGARLTELMKQPQYSPLTNSEIVCIIFAGTNGYLDKVDVKEVGRYEAELLTFLRSKKADFLQWITDEDPKFKKGEPVEKMKAVLDEFAADFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PRMA_BACAH
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_STRGG
Sequence: MARVKRAVNAHKKRRAILEAASGYRGQRSRLYRKAKEQVTHSLVYNYNDRKKRKGDFRQLWIQRINAAARQNGMTYNRLIQGLKAANIEVDRKILAELAVNDANAFAALVEVAQKALPSDVNAPKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: QCR9_SCHPO
Sequence: MASSTIYNIFFRRNSSFYATIFVSAFFAKIGFDVFTDSVWKRANAGLTWDEVKPRFLNKDEDAEDDE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 9, Complex III subunit 9, Cytochrome c1 non-heme 7.3 kDa protein, Ubiquinol-cytochrome c reductase complex 7.3 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RK23A_AGRST
Sequence: MDNGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRIGPILGHTMHYRRMIIILQPGYSIPLLDREKN
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23-A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: APC15_SCHPO
Sequence: MSFMSLMANTAHQLWYPTSFPSMKELEKEEVRLETQELAIKQFGFRTIRPIGLNRSMQEQLDLEEQEREEANQDTELDEEELGSGSFPEEGEMDDMDGDNEEVEDHDIEEVDLDADITNADASEFYEDISEYGFQN
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.
What are the official names of this protein?
Anaphase-promoting complex subunit 15, 20S cyclosome/APC complex protein apc15.
What is the protein family that this protein belongs to?
Belongs to the APC15 family.
Protein: FABZ_STRPZ
Sequence: MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFFNGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_NEIG1
Sequence: MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEAAEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTEKLGKKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKCNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAAYYPGKAAFYQLGK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRPB_CLAMS
Sequence: MTDLRSVTGPYFGEFGGRYVPESLVAALDELSAAWEELKVDPAFVEELKELHRTYTGRPSLITEVPRFAEHAGGARIILKREDLNHTGSHKINNVLGQALLTKKIGKKRIIAETGAGQHGVATATAAALFGLDCVIYMGEVDTERQALNVARMRLLGAEVIPVRSGSRTLKDAINDAMRDWVTNVETTNYVFGTVAGPHPFPAMVRDLQKVIGEEAREQVLALTGRLPDAVAACVGGGSNAIGIFHAFLDDADVALYGFEAGGDGADTPRTAATITKGRPGMLHGARSYLLQDEDGQTIDSHSISAGLDYPGVGPEHSWLSDLGRASYRPVTDDQAMSALRLLSRTEGIIPAIESAHALAGALELGKELGPDAIILINLSGRGDKDMETAGKYFDLIDAGAEQS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ITA1_RAT
Sequence: MVPRRPASLEVTVACIWLLTVILGFCVSFNVDVKNSMSFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKARTGDVYKCPVGRERAMPCVKLDLPVNTSIPNVTEIKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSFAPVQECSTQLDIVIVLDGSNSIYPWESVIAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAANKIGRQGGLQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNYRLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKALGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKANQMVIPHNTTFQTEPAKMNEPLASYLGYTVNSATIPGDVLYIAGQPRYNHTGQVVIYKMEDGNINILQTLGGEQIGSYFGSVLTTIDIDKDSYTDLLLVGAPMYMGTEKEEQGKVYVYAVNQTRFEYQMSLEPIRQTCCSSLKDNSCTKENKNEPCGARFGTAIAAVKDLNVDGFNDVVIGAPLEDDHAGAVYIYHGSGKTIREAYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWARDVAVVKVTMNFEPNKVNIQKKNCRVEGKETVCINATMCFHVKLKSKEDSIYEADLQYRVTLDSLRQISRSFFSGTQERKIQRNITVRESECIRHSFYMLDKHDFQDSVRVTLDFNLTDPENGPVLDDALPNSVHEHIPFAKDCGNKERCISDLTLNVSTTEKSLLIVKSQHDKFNVSLTVKNKGDSAYNTRTVVQHSPNLIFSGIEEIQKDSCESNQNITCRVGYPFLRAGETVTFKIIFQFNTSHLSENAIIHLSATSDSEEPLESLNDNEVNISIPVKYEVGLQFYSSASEHHISVAANETIPEFINSTEDIGNEINVFYTIRKRGHFPMPELQLSISFPNLTADGYPVLYPIGWSSSDNVNCRPRSLEDPFGINSGKKMTISKSEVLKRGTIQDCSSTCGVATITCSLLPSDLSQVNVSLLLWKPTFIRAHFSSLNLTLRGELKSENSSLTLSSSNRKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK
What is the function of this protein?
Integrin alpha-1/beta-1 is a receptor for laminin and collagen.  It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.  Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth (By similarity).
What are the official names of this protein?
Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.