PharMolix/UniProtQA huggingface dataset:
Protein: PURE_METJA
Sequence: MICIIMGSESDLKIAEKAVNILKEFGVEFEVRVASAHRTPELVEEIVKNSKADVFIAIAGLAAHLPGVVASLTTKPVIAVPVDAKLDGLDALLSSVQMPPGIPVATVGIDRGENAAILALEILALKDENIAKKLIEYREKMKKKVYASDEKVKEMFK
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: PETM_PROM4
Sequence: MASEIFGTAAVFWVLIPVGLLGGAILLKLQGD
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SOXA_PARPN
Sequence: MPRFTKTKGTLAATALGLALAGAAFADPVEDGLVIETDSGPVEIVTKTAPPAFLADTFDTIYSGWHFRDDSTRDLERDDFDNPAMVFVDRGLDKWNAAMGVNGESCASCHQGPESMAGLRAVMPRVDEHTGKLMIMEDYVNACVTERMGLEKWGVTSDNMKDMLSLISLQSRGMAVNVKIDGPAAPYWEHGKEIYYTRYGQLEMSCANCHEDNAGNMIRADHLSQGQINGFPTYRLKDSGMVTAQHRFVGCVRDTRAETFKAGSDDFKALELYVASRGNGLSVEGVSVRH
What is the function of this protein?
C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation.  The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates.  This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain.  Some electrons may be used for reductive CO(2) fixation.
What are the official names of this protein?
L-cysteine S-thiosulfotransferase subunit SoxA, Cytochrome c551 subunit diheme, Protein SoxA, SoxAX cytochrome complex subunit A, Sulfur oxidizing protein A, Thiosulfate-oxidizing multienzyme system protein SoxA, TOMES protein SoxA.
What is the protein family that this protein belongs to?
Belongs to the SoxA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: WRK36_ARATH
Sequence: MIKEETVSYFQTFDGVMAESDKEEELDATKAKVEKVREENEKLKLLLSTILNNYNSLQMQVSKVLGQQQGASSMELDHIDRQDENNDYDVDISLRLGRSEQKISKKEENKVDKISTKNVEESKDKRSALGFGFQIQSYEASKLDDLCRQVKLANAENKCVSSRKDVKSVRNENHQDVLEEHEQTGLKKTRVCVKASCEDPSINDGCQWRKYGQKTAKTNPLPRAYYRCSMSSNCPVRKQVQRCGEEETSAFMTTYEGNHDHPLPMEASHMAAGTSAAASLLQSGSSSSSSSTSASLSYFFPFHHFSISTTNSHPTVTLDLTRPNYPNQLPDDYPLSSSSFSLNFSSPDPPPPSSHDHTLNFSGLRTQAPLSTDSLLARYRTRLSGQQ
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 36, WRKY DNA-binding protein 36.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEC24_ASPTN
Sequence: MAAPQGGYPPQEGYGQPAAYGSPTQQQAPTPVQHGGKKKRAYAGEAFEFGSGANAALGGQLPAGGSYGAYPQQQAGYQQPAAYGADPAQAYAAPAAPGVAQMTQQFGAMGMTDPHLLPPQPAPQAPQAPRTVPLNQLYPTDLLSQPFNVAELDYPPPPIVLPPGTSVYPSPYANCPPKYVRSTLNAVPTTHSLLKKSKLPFALVIQPYAALHDSEDPIPVIPDQVISRCRRCRSYINPFVTFLDHGHRWRCNMCNLTNDVPQAFDWDTALQKPADRSLRPDLNHSVVEFVAPQEYMVRPPQPLVYLFLIDVSYASVTNGLLATSARCIKESLDRIPNADRRTRLGFIAVDSSLHYFSIPRDGSENSNPQMLVVSDLDEPFLPIPGDLLVTLSECRENIESFLDKLQEMFQNTQNNGCAMGSALRAGYKLIAPVGGKMTVLSSSLPNVGHGALTMREDKKVLGTSKESSLLQTANSFYKSFAVECSKAQVSVDMFLFSSQYQDVASLSNLPRYTGGQTYFYPGWNAARGEDAIKFAREFSDYLSSEIGLEAVLRVRATTGLRMNTFYGNFFNRSSDLCAFPAFPRDQAYVVEVAIDETITRPVVCLQTAVLHTTCNGERRIRVLTLALPTTQNLADVYASADQQAIATYFSHKAVERALGSGLEPAREALQSKIVELLATYRKELAGGSVSGGGLQFPANLRGLPVLFLAMIKNLGLRKSAQIPTDMRSAALCLLSTLPLPLLMQYIYPKMYSLHDMPDVAGLPDEKTGEIVLPPPVNLSSERVVPYGLYLIDDGQTQFLWVGRDAVPQLVLDVFGLPDKSQLRVGKQNLPDLDNDFNQRVRAVVEKSRDHRSKGVGSIVVPHLYVVKEDGEPGLRLWAQTMFVEDRADQSVSLVQWMGSLREKV
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPG_ACIF2
Sequence: MHHESPIRRRKTRQIHVGKVAIGGDAPISVQSMTNTETRDIAATVAQIRRLEAVGADIVRISVPSMDAAEAFKTIRAQVETPLVADIHFDHRIALQVMEDGVDGLRINPGNIGSLDKTRLVVEMAKDKGIPIRIGVNAGSLEKDIQEKYGEPTPEALVESALRHVSILDELNFHDVKISVKASDIFLAVSAYRLLSEKVDYPLHLGITEAGGLRSGTVKSAIGLGLLLRDGIGDTIRVSLAADPVEEIRVGFDILKSLHLRQKGINLIACPSCSRQEFDVITTINALEARLEDILEPMDVSVIGCVVNGIGEAKEADIGLAGGDKRSILYYRGKQVDRVENNDIVDVLEKRIRAEIAERQATRHEG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MURB_BURCM
Sequence: MPMPPDDSALSLLPDHPLAAHNTFGIDATARFAARITHAAQFAALHRDPRVAHLPQLVLGGGSNVVFTRDFDGIVLLDEIAGRRVVREDDDAWYVEAGGGETWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKTYFDSLVAVELATGRSERFDAARCAFGYRDSFFKREGRGRFAIVAVTFRLPKRWTPRLGYADVTRELDARGIAPEAATPRDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAARFDALRARVPDVVSYPQPGGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGADVLALARAIQDDVRKQFGVELEPEPVCV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQJE_ECOLI
Sequence: MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
What are the official names of this protein?
Inner membrane protein YqjE.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_FRATM
Sequence: MVVIRMARGGAKKRPFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RUTF_ECO5T
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQNGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: WTIP_XENLA
Sequence: MEKYDEDIALQASKFLEDLSLCDGHSRLYGPVGDMLLSNDHILVADHRGRRLNGSLTQYLPHSSSDKVYPLGSSQLRSMNGSRGDGYMDEGIYKSDVALPCYSGISEKNKRYSAELYRHSCGNSFEGVPISAKQGGITALYSGGKMSNSCMSATSPRSSMASSASSSQEHSKYSSPRSSISSNALSLDKFSSPRSSLVVPGQQEKYTSPRSSLGQYEGGVLSPRSSYASTTSDTSKHSSPRASLTSYDCGSKPSSNRTSGISMGYDQRHISPRSSTASQYSCTTSPRSSYSDSRYVPSGNPDLDGVGGHGSLVSPRSSMCLQEGRSATLGSCNPSVVSPRSSISSHSSRSSRSSRGSMGAYTDLTVPSPRSSMLGTSLQEETLVQDLGEACHYKVLTQSPPRQEQHQTITSSHDLNSGAVASYNFSSAKGSATVHRFKLPYQVTPSRESGPSQAERRLEALTLELEKELELHMKKEYFGICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYHCEDCQLQLNDEEGRRCYPLEGHLLCHSCHIRRLSVNVPPHQPPSYPMHVTEL
What is the function of this protein?
May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes.  In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator.  Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).  Acts as a transcriptional corepressor for snai1 and snai2/slug and plays a role in regulating neural crest development.  Involved in the organization of the basal body (PubMed:27062996).  Involved in cilia growth and positioning (PubMed:27062996).
What are the official names of this protein?
Wilms tumor protein 1-interacting protein homolog, WT1-interacting protein homolog, xWtip.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Nucleus.
Protein: RNB_HAEI8
Sequence: MFQDNPLLAQLKQQIHDSKEQVEGVVKSTDKAYGFLECDKKTYFIAPPSMKKVMHGDKIKATIEKQGDKEQAEPEALIEPMLTRFIAKVRFNKDKKLQVLVDHPSINQPIGAQQAKSVKEELQEGDWVVANLKTHPLRDDRFFYATINQFICRADDELAPWWVTLARHEQSRYPVQGAEHYEMLDQKTRENLTALHFVTIDSESTMDMDDALYIEPIAQNSTQTGWKLVVAIADPTAYIALDSQIEQEAKQRCFTNYLPGFNIPMLPRELSDELCSLIANETRPALVCYIETDLAGNITAKPHFVSAYVQSKAKLAYNKVSDYLEQADNAWQPETPETAQQIHWLHQFTKARIQWHKTHSLLFKEKPDYAFVLAENGKVQEIKAEYRRIANQIVEEAMIIANICAAQFLHEQAKTGIFNTHSGFDKKFLENAHHFLMANLANEQNQTELAERYSVENLATLNGYCQMRHDIEPIESDYLELRLRRYLTFAEFKSELAPHFGLGLEGYATWTSPIRKYSDMVNHRLIKAVLAKQPYEKTQNDVLARLQEARRQNRLVERDIADWLYCRYLAPKVAENVEFNAEVQDVMRGGLRVQLLENGASMFIPASTLHNNKEEMQVNSDEIALYIKGERTYKIGDIVKVKLTEVKEATRSIVGEILQ
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_TERTT
Sequence: MKLLVDAGNSRIKWWVPECQAHGVVDRLALDDLAGEIAAVIDISKLSSVRVSCVAGKSIETQLRGELGFARDLDVKFARVSSPLPILTVAYREIHRLGVDRWLAMLAVREKFPDRFCAVLDAGSAVTVDFVTEAGVHEGGMIVPGVQTMARALWSNTSDVAVERLELVPRWCPGVDTYDCVRQGVSALYTGLVNEVHSYIDGSAERHLSPAIVVTGGDRHWFTQAFSSPVVVDPHLVLKGLLVLDELEK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BRUA2
Sequence: MKRSASDSPLLFDLPLAPDFSQEQQLMKRGLKHIAGIDEAGRGPLAGPVVAAAVVLDQNDLPEGLDDSKRLTAARREALYEIILTKAITVSVASLSARSIDASDIRKAALEAMRRAVIGLTLKPCHALVDGRDVPPGLPCPGSALVKGDQRSVSIAAASIVAKVTRDRMMIRAGAAHPPYGLEIHAGYATQKHRAAIESEGPVPGLHRYTFAPIKGCFDC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZE_STAAW
Sequence: MLSFSQNRSHSLEQSLKEGYSQMADLNLSLANEAFPIECEACDCNETYLSSNSTNE
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity.
What are the official names of this protein?
Antitoxin MazE.
What is the protein family that this protein belongs to?
Belongs to the MazE/EndoAI family.
Protein: PER2_ORYSI
Sequence: MASASSVSLMLLVAAAMASAASAQLSATFYDTSCPNALSTIKSAVTAAVNSEPRMGASLVRLHFHDCFVQGCDASVLLSGQEQNAGPNAGSLRGFNVVDNIKTQVEAICSQTVSCADILAVAARDSVVALGGPSWTVLLGRRDSTTANESQANTDLPAPSSSLAELIGNFSRKGLDVTDMVALSGAHTIGQAQCQNFRDRLYNETNIDSSFATALKANCPRPTGSGDSNLAPLDTTTPNAFDSAYYTNLLSNKGLLHSDQVLFNGGSTDNTVRNFSSNTAAFNSAFTVAMVKMGNISPLTGTQGQIRLNCSKVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCND1_DANRE
Sequence: MEHQLFCCEVDTIRRAYQDSNLLNDRVLQTMLKAEENYLPSPNYFKCVQKEIVPKMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPGELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQILRKHAQTFVALCATDVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLTNFLSQVIRSDPDCLRSCQEQIESLLESSLRQAQQHISTETKRVEEDVDLSCTPTDVRDINI
What is the function of this protein?
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
What are the official names of this protein?
G1/S-specific cyclin-D1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HSP60_PARBA
Sequence: MQRAFTSSRASVLSSASSTRAPLSRFRSAGVGLQQQRFAHKELKFGVEARASLLKGIDTLAKAVTTTLGPKGRNVLIESPYGSPKITKDGVTVAKAVTLQDKFENLGARLLQDVASKTNEVAGDGTTTATVLARAIFSETVKNVAAGCNPMDLRRGIQSAVEAVVEYLQTNKRDITTTEEIAQVATISANGDTHVGKLISNAMEKVGKEGVITVKDGKTIDDELEVTEGMRFDRGYVSPYFITDTKAQKVEFEKPLILLSEKKISAVQDIIPALEASTSLRRPLVIIAEDIEGEALAVCILNKLRGQLQVAAVKAPGFGDNRKSILGDIGILTNATVFTDELDLKLEKATPDMLGSTGSITITKEDTIILNGEGSKDAIAQRCEQIRSVISDPATSDYEKEKLQERLAKLSGGVAVIKVGGASEIEVGEKKDRVVDALNATRAAVEEGILPGGGTALLKAAANGLTSLNPTNFDQKLGISIIKNAITRPARTIVENSGLEGSVIVGKLTDDFAGDFNRGFDSARGEYVDMIGAGIVDPLKVVRTALVDASGVASLLGTTEVAIVEAPEEKVPAGSGAGGMGGGMGGMGGGMF
What is the function of this protein?
May participate in assembly and/or disassembly of proteins imported into the mitochondrion.  HSP60 are ATPases and have affinity for unfolded proteins (By similarity).
What are the official names of this protein?
Heat shock protein 60, mitochondrial, 60 kDa chaperonin, Protein Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMD_SALTY
Sequence: MAQFYSAKRRVTTRQIITVKVNDLDSFGQGVARHNGKALFIPGLLPEESAEVIITEDKKQFARARVSRRLNDSPERETPRCPHFGVCGGCQQQHVSIALQQRSKSAALARLMKHEVNDIIAGAPWGYRRRARLSLNCPPDKPLQMGFRKAGSSDIVNVEQCPVLAPQLAALLPRIRACLASLHGTRHLGHVELVQAGSGTLMILRHTAPLSAADKEKLERFSHSEGLSLFLAPFSEILETVSGEAPWYDSHGLRLAFSPRDFIQVNEAVNQQMVARALEWLDVRAEDRVLDLFCGMGNFTLPLATRAASVIGVEGVPALVEKGRENAIRNGLHNVTFFHENLEEDVTKQPWAKNGFDKVLLDPARAGATGVMRHIIKLKPIRIVYVSCNPATLARDSEALVNAGYEVTRLAMLDMFPHTGHLESMVLFERM
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: PTHR_CHICK
Sequence: MMFTKLFQQWSFAVFLLSYSVPSYGRSVEGISRRLKRAVSEHQLLHDKGKSIQDLRRRIFLQNLIEGVNTAEIRATSEVSPNPKPATNTKNYPVRFGSEDEGRYLTQETNKSQTYKEQPLKVSGKKKKAKPGKRKEQEKKKRRARSAWLNSGMYGSNVTESPVLDNSVTTHNHILR
What is the function of this protein?
Osteostatin is a potent inhibitor of osteoclastic bone resorption.
What are the official names of this protein?
Parathyroid hormone-related protein, PTH-rP, PTHrP.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted.
Protein: HIFC2_HAEIF
Sequence: MKTKNFPLNKIAFACTLLLANPVAWAEDQFDASLWGGGSVLGIDFARFNVKNAVLPGRYEAQIYVNNEEKGESDIIFADNPATGRAELCFTPKLQEMLDLMDEAIVKSPNAEDDTCVFASEAIPKGTFDYQGGDMKLKLELPQALTIRRPRGYIAPSRWQTGTNAASANYDINYYRSGNPEVKSKSLYVGLRGGVNLGNWALRHNGSFSRFENHSSSGFTDKGKNHYERGDTYLQRDFALLRGNVTVGDFFSTARIGESFGLRGLRIASDDRMLAPSQRGFAPVVRGVANTNAKVSIKQNGYTIYQITVPAGPFVINDLYASGYSGDLTVEIQESDGKVRSFIVPFSNLAPLMRVGHLRYQLAGGRYRIDSRTFDERVLQGVLQYGLTNHLTLNSSLLYTRHYRAGLFGFGLNTPIGAFSADATWSHAEFPLKKVSKNGYSLHGSYSINFNEIGTNLTLAAYRYSSRDFYTLSDTIGLNRTFKQFSGAYLPEIYRPKNQFQVSLSQSLGNWGNLYLSGQTYNYWEKRGTNTQYQLAYANRFHILNYSINLSQSIDKETGKRDNSIYLSLSLPLGDNHSADSSYSRSGNDINQRLGVNGSFGERHQWSYGINASRNNQGYRSYDANLAHNNSIGSYRASYSRDSLKNRSTSLGASGAVVAHKYGITLSQPVGESFAIIHAKDAAGAKVESGANVSLDYFGNAVVPYTSPYEINYIGINPSDAEANVEFEATERQIIPRANSISLVDFRTGKNTMVLFNLTLPNGEPVPMASTAQDSEGAFVGDVVQGGVLFANKLTQPKGELIVKWGERESEQCRFHYQVDLDNAQIQNHDIQCKTAE
What is the function of this protein?
Essential for piliation.
What are the official names of this protein?
Outer membrane usher protein HifC.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: HEMA_VAR67
Sequence: MTRLSILLLLISLVYSTPYPQTQISKKIGDDATLSCSRNNINDYVVMSAWYKEPNSIILLAAKSDVLYFDNYTKDKISYDSPYDDLVTTITIKSLTAKDAGTYVCAFFMTSTTNDTDKVDYEEYSTELIVNTDSESTIDIILSGSSHSPETSSEKPDYINNFNCSLVFEIATPGPITDNVENHTDTVTYTSDIINTVSTSSRESTTVKTSGPITNKEDHTVTDTVSYTTVSTSSEIVTTKSTANDAHNDNEPSTVSPTTVKNITKSIGKYSTKDYVKVFGIAALIILSAVAIFCITYYICNKRSRKYKTENKV
What is the function of this protein?
Prevents cell to cell fusion by interacting with and directing the viral OPG040 protein on the host plasma membrane.  The OPG185-OPG040 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation.  Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack.
What are the official names of this protein?
Protein OPG185, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG185 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single- pass type I membrane protein. Note=Component of extracellular enveloped virus (EEV) but not intracellular mature virus (IMV). Component of the outermost membrane of EEV.
Protein: NUCD2_AQUAE
Sequence: MKWVNKGTVERVKQEFKDEVKYYETKHTKGFEVSHDFLKPLLKFLKERERFLHFVDMTCIDFPEHPNRFQGVYILYNPEENERVIVKSWAKDGKLPTVEDLWPGAKWAEREAYDMFGVVFEGHENLRRMFMWEGYEHYPLRKDFPLQGIPEVELPSLTEVLHGRTDPPSHDFELVHTKLPTLEDLERTEKARLKKKAELVLNWGPLHPGTHGTIWFLFDLEGEKVVQSDVILGQLHRGMEKLAENLHYFQFIPYTDRMDYISAICNELAYVETVERLLGVEVPEKARYIRTMFAELQRINSHLLWLGTGALDLGALTVFLYAFREREKIMDIIEGNAGYRLTSCFLRIGGVHYDLAEGTLDVVKHFIKDFPNRLKEYHTLLTRNRIWLRRTKDVGVITREDVHNYGLSGPVARGSGVPYDLRKLQPYAAYDEVEFDIPVGEVGDVYDRYLVRMEEMAQSVRIIEQCVQKLEKLPKDAPYLNKEHPAVIPPKEDVFHDLESMVKSFRVVVHGEDAPPGEVYFAGENPRGELGFFIYSKGGGKPYRTRIRSGALYNLSIFPKLIQGRTIADAIALLGSLDPVVGETDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D 2, NADH dehydrogenase I subunit C/D 2, NDH-1 subunit C/D 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAPSA_BPT3
Sequence: MANIQGGQQIGTNQGKGQSAADKLALFLKVFGGEVLTAFARTSVTMPRHMLRSIASGKSAQFPVIGRTKAAYLKPGENLDDKRKDIKHTEKVIHIDGLLTADVLIYDIEDAMNHYDVRAEYTAQLGESLAMAADGAVLAELAGLVNLPDGSNENIEGLGKPTVLTLVKPTTGSLTDPVELGKAIIAQLTIARASLTKNYVPAADRTFYTTPDNYSAILAALMPNAANYQALLDPERGTIRNVMGFEVVEVPHLTAGGAGDTREDAPADQKHAFPATSSTTVKVALDNVVGLFQHRSAVGTVKLKDLALERARRANYQADQIIAKYAMGHGGLRPEAAGAIVLPKVSE
What is the function of this protein?
Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins.  The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively.  Once the capsid formed, encapsidates one single copy of the viral genome.
What are the official names of this protein?
Major capsid protein, Gene product 10A, Gp10A, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the T7virus major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: PYRD_BUCAP
Sequence: MFYYLIRKLLFLIDPEKAHTLVLMYLNSKKIQILRKIFIKPIPLKQIKCMGLTFNNKIGLAAGMDKNGDYIDSLSKIGFGFIEVGTVTPLPQYGNPKPRIFRVPSIEGIINRMGFNNLGIDYLVNNVKKSKFKGIIGINIGKNKDTKIEDAIKDYLICIEKIYFYASYIAINISSPNTINLRKLQYGILFENLLRDIKKKQSEMHSKYSKYVPIVIKISPDLSKKELIHISNKLIHYKIDGVIATNTTLDHSSIPKIKNNKEEGGLSGLPLQKKSNDVISILYKNLKRKIPIIGVGGINSINSAREKIMCGANLIQVYSGLIYHGPNFIREIIRNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBIB_SHEPC
Sequence: MTLTSIRRGYHVIKTLLQYGLDEVLPPKMTPWYFTLARSSLFWIRNKHKSKPGGERLKLAMQELGPVYIKLGQMLSTRRDLLSDEWAIELAMLQDKVPPFDGVLARKAIEAELKASIESLFDDFDETPLASASISQVHTATLKSNGKAVVLKVLRPNVEAKILADLQLMSQTANLLEYFLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAIKLRNNFLNSDALYVPYVYEEFCYPRLMVMERIYGIPVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARSFDIVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMAEQVGPKAMFKKVSTKLPYWSDKLPEFPELIYDNLKLGRKLLSSQQQMLDKYLKHQQQAHKSNYMLITSAVLLICGTLLFNQDATLWSPYVCLTSGVLMWFIGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1654_METJA
Sequence: MGYPTPIKLGLSAPINVPLIYKTGEKMRYVAYKIYPEEFLNNEVVDNALIIEGRKVRRVRILGKVENINVGNIISFYVDGVNVRYFEEKPVYIEEGDIVDVIGRPRTYDGEKYIMAEIIRKRDERWIKLRDLEIKKTRKYLLERAELYEEENEEMSLEEEVYTEILNSDVIKDKILAIIENVGEITYEELAEKINIPEEDLEKYLSELKESGDIFEPRPGVYKVL
What are the official names of this protein?
Uncharacterized protein MJ1654.