PharMolix/UniProtQA huggingface dataset:
Protein: TBG_ENCCU
Sequence: MREVVTLQVGQCGNQMGAEFWKTLCKEHGISMCGVLQDSRDLGDRKDVFFYQADDNVFVPRAILVDLEPRVISQAPSFFSQESIFLSNEGGGAGNNWGHGYCVGKAMGNDVIDMIQREAEGCDALETFLLLHSIAGGTGSGFGSLLLERIKEEFPKKIVQTYSIFPNNDESSDVVVQPYNSVLTLHRLIENSDCIVVMDNSSLGRYTLDSLRIGTPTFDHINLLISTVMAASTSTIRFPGYMYCTHQSINNCLVPLDPLKFVVPSYTPFVCDEMSRVVRKATCSDVMRRLLLPKTRLAGYEQTKAQSVVSMLNILHGVEDSGEVSRTVMRFLDKGMVNFVPWMPPSFNVALGKCIANETRPSRVSGLSLTNSTGASLILSKISGQFDKLRKQRAFLDIYKRFGVEPEMFDEGKEIVQKALEEYHSAEMAAYPNH
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity).
What are the official names of this protein?
Tubulin gamma chain, Gamma-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: PHR_DICDI
Sequence: MLLLNYTQNFQLITFLLFPFINTFDYNCLKPTTTTTTSPTSSKLGFLNRSKSNSNININELKNKFLEQQQEGSISNIAGVATTQQNPSIVINSSSSSSSSSSHHPHHQKTPSNSSSNFNLIKASFNQIGVAFNNNISPRSNRKEKEKDKDKDHQDNSNINNINNINNNINNNINNNNNNNNNNNNNNNMHNPTSSSPSINNNLKGKNVASIIAANGANLNNSLSNLHQHVNNNSNNNLTNSFNSVSHNNISISSGGSALSYNYTQQLNQNGGSNNGSTSNSTSNSANNSLLSLASSINGNIGSDENGSNVMYGGDIASSYHSMSIDPLKSSTNTETIEIMVVGDELSNKARFISSFLNNGIGEDPTLEISTKKSIAIQSGAYNVNINTTVGQEEFWGINDVYYRSSQGFIFVYNVNSRESFLSFLKFRDKIIHEKGTENILMAMVGLTSPLINQESGEESCIREVTQQEAKRMADLYSCSFVELNSFGLDCEHQIQSIVTDLLGRITSGLSSTNNNNSGNNSNNNNGNSNGNSSNNNSNNNSTNNLNNSAILNESIAQSIEVLMLGDIFVGKTQIIQRLLGNPFQNAYKETTEWNRNVYQMTVNDVRYLLKIVDTCGLDIEETLNRERLVSTQGFIFVYSIASRESFLMIEQLRKKLSSIKSETKIPSVLIANKGDSLIRQVTFDEGSKMAQHLGSHYFEVSSMFSDDESIGRPFEQLLIDIQKSGNASGFEPSEIKKKGYLFKEGKKLKSMSKYFFKASRGNLSYCKNESNKSKVKSIQLSEQIQLAIPHNVHEKKDVWPFSIILDPVSKHSINLIASTEEERNAWIKAIKFNCFLEDITSNIIDDVVKSMVSEIASGVAGSGSNNGNNNGHLKRSDTTQQLNNSGSFINGINANKPVPNFSNLSISGGGSSNNSNNSTPMSSPYGSSNNFSSHLSQSTSSMSMSPQQQLQSVLLSSSNLSSSMNSSFSYSSSISSSYTDSMSGSPPDSNGQVFPQSPQLKKTLFQRTTSFSKGSKLK
What is the function of this protein?
Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808).  The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808).
What are the official names of this protein?
Sca1 complex protein phr, Pleckstrin homology domain-containing protein.
What are the subcellular locations of this protein?
Cell membrane. Note=The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells (PubMed:20493808). Membrane localization of the Sca1 complex is regulated by scaA phosphorylation by PKB and PKB-related PKBR1 (PubMed:20493808).
Protein: RM35_BOVIN
Sequence: MAASMFAGAVRAASGILRPLNILASSAYRNCTKNACLNSILSSRHFSHIQTPVVSSAPRLITSVRNLTCGQTATVLNRMALLLPNVLKPPVRTVTYCSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTVARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQMYHDRTNLKV
What are the official names of this protein?
39S ribosomal protein L35, mitochondrial, L35mt, MRP-L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YLAT2_DANRE
Sequence: MQLKKEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLSLVIWAIGGIFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQPLFPTCEPPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKLCQGFTINFEDSFQGSSRDPGGIALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTIIYILTNVAYYAVLDMSAILASDAVAVTFADHTLGVMSWTIPIAVALSCYGGLNSSIIAASRLFFVGAREGHLPDALSMIHIERFTPVPALLFNCAMALIYLTVEDVFQLINYYSFSYWFFVGLSIAGQIYLRWKEPDRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDTLNTLIGIAIALSGVPVYFLGIHLPESKRPPIITKLLSAITRFTQFTCFYVLTEMDTVD
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids such as L-arginine from inside the cells in exchange with neutral amino acids like L-leucine, L-glutamine and isoleucine, plus sodium ions and may participate in nitric oxide synthesis.  Also exchanges L-arginine with L-lysine in a sodium-independent manner.  The transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (By similarity).  Contributes to ammonia-induced increase of L-arginine uptake in cerebral cortical astrocytes leading to ammonia-dependent increase of nitric oxide (NO) production via inducible nitric oxide synthase (iNOS) induction, and protein nitration (By similarity).  May mediate transport of ornithine in retinal pigment epithelial (RPE) cells (By similarity).  May also transport glycine betaine in a sodium dependent manner from the cumulus granulosa into the enclosed oocyte (By similarity).
What are the official names of this protein?
Y+L amino acid transporter 2, Solute carrier family 7 member 6, zfSlc7a6, y(+)L-type amino acid transporter 2, Y+LAT2, y+LAT-2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: NADA_STACT
Sequence: MFNPILSVSKSIPEKYLQMSQEELENHIQAIKDQLGNRLFMPTHHYQKNEVVQFADITGDSLELARICKENTEAEYFVFNGVHFMAETADILTDDSQDIYLPDLSAGCSMADMANITQALHGYDVLTEKFHLDILPLTYVNSTAAIKKFVGEHGGSCVTSGNAKSVVDWALNQGKVILFLPDQHLGRNTAYDLGIPLEQMAVWDPIAKELIYEGDLEDLRIVLWKGHCSVHEKFHKAHIDMARERDPEINVIVHPECEFEVVQAADYAGSTRYIIETIKNAPKGSRWLIGTEMNLVNRLKETYTDITIDSLNPLMCSCLTMNRIDLPHLAWCLDKILDGNKDNIIKVDAETAKYAKESLDRMLSIT
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHS_METJA
Sequence: MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGANAVLLHKGIVRHGHRGYGKDVGLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHVNVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQNERDPELVAHAARLGAELGADIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNIFQHDDVVGITRAVCKIVHENADVEEALKEIRKK
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.  Can also catalyze the cleavage of fructose-1,6-bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase, Transaldolase-like ADHS.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: FAR15_SARBU
Sequence: THDFMRF
What are the official names of this protein?
FMRFamide-15, SabFMRFamide-15.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: UGPC_RUEST
Sequence: MASITLKDLVKSYGDTEVLHHIDGEINDGEFIVIVGPSGCGKSTLLRMIAGLETVTSGDIKICDRVVNDLEPANRDIAMVFQNYALYPHMSVRENMGYGLKIRGNSKADINRRVEEAAEILEIGQYLDRKPRQLSGGQRQRVAMGRAIVRDPQVFLFDEPLSNLDAKLRVQMRLEIRKLQQRLGVTSIYVTHDQVEAMTLGDRLMVLNGGYVEQFGTPIELYDRPATLFVAGFIGSPSMNFLPAEIDAGMVTLENGARLAGGGSAAGKVTLGLRPEHLVADDNGPVEVNVQLCEQLGAITLLHGHLNGTDTECVASMPGHVTAAPGTLMRFSIAPENLHMFDPQTGKRVAE
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YENI_YEREN
Sequence: MLKLFNVNFNNMPERKLDEIFSLREITFKDRLDWKVTCIDGKESDQYDDENTNYILGTIDDTIVCSVRFIDMKYPTMITGPFAPYFSDVSLPIDGFIESSRFFVEKALARDMVGNNSSLSTILFLAMVNYARDRGHKGILTVVSRGMFILLKRSGWNITVLNQGESEKNEVIYLLHLGIDNDSQQQLINKILRVHQVEPKTLETWPIIVPGIIK
What is the function of this protein?
Required for the synthesis of autoinducer molecules such as OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone).
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein YenI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: KAD_SHEPW
Sequence: MRIMLLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGQLVSDELIIGLVKERVAQDDCAKGFLLDGFPRTIPQADAMAAGGIAIDHVVEIDVPDEEIVKRMGGRRVHPGSGRVYHIVFNQPKVEGKDDVTGEDLAIRPDDEEATVRKRLDIYHEQTKPLVEYYGAVAAKGEATYNKFDGTQSVAKVSEEIVAALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL39_ARATH
Sequence: MSYFKRNEGTIVFAFASIGFIAFYIINYYIRRCRNRAAAAGDIEEARMSPRRPPRGLDAEAIKSFPSFVYTEARGIEPGIGELECVVCLNEFKDDETLRLVPPCVHVFHADCVDIWLSHSSTCPICRAKVVP
What are the official names of this protein?
RING-H2 finger protein ATL39, RING-type E3 ubiquitin transferase ATL39.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYP_AQUAE
Sequence: MRWSRYFLYTEKEEPKEAEAPSHRLLLKAGFIKQVSAGIYELLPPAYKVLKKVESIIRKEMDRSGAQELLLTVLNPKELWEETGRWETYGEELFKLKDRNGREYCLGPTHEEEITDLVRRVVRSYRQLPVILYQIQVKFRDEKRPRFGLIRAREFIMKDAYSFDTDDMSAMISYEAMKFAYQRIFNKLRLNVIMAEADVGQIGGKMSHEFIAFTDYGEAKVAYCENCGYAANAEIVPLPKPEEEKEEEKPMEKVHTPNVHTIEELSKFLDVHPSKIMKAVLYIVNEKEPVLVLIRGDREIDENKLEKVLGTDNFRLATDEEVQELLGTKKGFIGIFNLPENIKVLWDNSLYGVKNLVVALNEPDWHYINVNPGRDFQYGEFVDVAEVREGDPCPKCGSPLKVRRGLELGHIFLLGTRYSEPMKAYFTDRDGKEKPIIMGCYGIGVSRILAALVEQYHDDKGIKWPTPVAPFELDIILLNTKDEEMKNVAEKLYLEAEEKGIDVIFDDREESPGFKFADADLVGFPYRIVVGKKVKEGKVEVQSRHTGEKWDVEIEKAIDFVKEKIEEDKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ANAMM
Sequence: MAISDNGGGSVGLCYGSEFSISDHWDKLTRPSSIKVVGDGDLSRSAELIVEPLESGFALTLGNALRRVMMSSLRGFAVYGIEVEGVSHELTSLSGVREDVADLVLNLSMLRVKLLTSESRVLRLVAKGPGEITAAAIGDSEGCVVLNKDLHICTLGKDVDFSMKIYVNSGKGYVPASEYRAASRSGATSEVGPGFIATNALYSPVKKVAFRIESSRIGQFTDYDRLVISVETDGSISPDEAVAVSARVLQDQLQSFIGSEEVEGESRKKVDKEEGALPYDHNLLRKVDELELSVRSHNCLKNDNITYIGDLVQKTESDMLRTPNFGRKSLNEINEVLASMNLHLGMKVPNWPPESIENLSKQYSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ORTA_UNKP
Sequence: MSEKCKKDDWVEIHYVVLEARERTGDIPEDTRKVPLECWIKGWAEKEGTVGEEVTIRTPANRYVKGTLTRINPEYTHTFGPCASELSAIGQELRATLKEGK
What is the function of this protein?
Involved in the ornithine fermentation pathway.  Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine.  It is strictly specific for AKP.
What are the official names of this protein?
2-amino-4-ketopentanoate thiolase alpha subunit, AKP thiolase, AKPT.
What is the protein family that this protein belongs to?
Belongs to the OrtA family.
Protein: RL7_BUCAI
Sequence: MSITKEQILEAISEMSVMNVVDLITAMEEKFGVSASMSINSNNHNEKDLREEKTEFDIFLKVIGPNKVSVIKTVRSATGLGLKEAKDLVESAPTVLKENISKEDAESLKKTLEDVGAEIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: YONE_BACSU
Sequence: MVTLNKVDIESEEYKQMLNDYSTYTSTFASGFISNMFSNGIVTEIEAEQLKNYFSNPDEFQEEIEDLAQYFYISTAEIHQLFELIEALPTLNYKIDSFNKVKSSDKHISLLNKSLHKVKHKRLTRDLLKQVATAGTLVGIWLGDAKSPYPFIFDEIKYVFPSFRRNGDWVCVVDMELFTKYKDDQRNELLKSLSPYIKQSDYENFMKDREKYRFKELPQERTFPLRTGTLKRNQGLGTSWVTPGLYDVLHKKKLKDVERSIANKIINAVAVLTIGTDKGNGEYTNMKLPKAVKQKIHGGVKTALEKNQKDGVTVVSIPDFADINFPDVKADGLDGAKFDHINSDIQSAYGLSGSLLNGDGGNYATSSLNLDTFYKRIGVLMEDIEQEVYQKLFNLVLPAAQKDNYYMNYDKDKPLTLKEKMDILIKLNDKGWSIKHVVDNLAGVSWESYLEQTLYETEELKLQEKIRPYQTSYTFTGNEVGRPNEGNKNNDNTVKSATSNGNDNPI
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YonE.
Protein: RL17_SALHS
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKTEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UVRD_SALTY
Sequence: MDVSYLLDSLNDKQREAVAAPRSNMLVLAGAGSGKTRVLVHRIAWLLSVENNSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQMRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWVRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAQTIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGVDGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQVCRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNDEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPLAENDTGYKLGQRVRHAKFGEGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYAKLETV
What is the function of this protein?
Has both ATPase and helicase activities.  Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present.  Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
What are the official names of this protein?
DNA helicase II, DNA 3'-5' helicase II.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: EFTS_ACIB5
Sequence: MTAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADGAITIVQDGNKAILVEVNCQTDFVAKDENFSNFAHTVAAAALAAGETDAAKIAELKLADGQSVEEARIALVQKIGENIQVRRAKIVEGEQLAIYKHGLKIGVVVSYTGDADTGKGIAMHVAAFNPVAVNAEAVPADLIAKEKEIAEAKALESGKPANIVEKMVTGSVEKYLNEVALDRQMYVIDNEKKVADVLKATGTNVANFVRFEVGEGIEKKAELSFAEEVAAAQAAAK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMN_CUPNH
Sequence: MIPSAITSPAPDRRALSDFRALAGRIDGNGPRYTSYPTADRFHNGPDLSLYHDALAACRADAPAPLSLYLHIPFCENICYYCGCNKIITRDHGRSARYVNYLGREMALVADRLGPRRQVLQSHWGGGTPTFLDPGEMRRVMALLHEHFELAAEGEHSIEIDPRRVDHARMALLAELGFNRVSLGVQDFDPEVQQAIHRIQPFEETRAVVDAARTLGFRSVSLDLIYGLPHQTAARFGRTIDQVLALRPDRLSVYSYAHLPHVFKPQRRIDENALPPAGEKLDILVSTIERLSAEGYVYIGMDHFALPDDDLAVAQREGRLQRNFQGYSTHAGYDQVGLGISAIGAIAGRYVQNARTLDEYYGALDHGRLPLARGVAMSADDHLRREIIGALMCNGVLDIPALEARHGIRFGTAFAPELADLAALGADGLVQCAPDRITVTPLGRLLVRRVAMVFDRYLREDAARPASTGAQAVAANDGAQPVRFVPRARYSRVV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLP_RICPR
Sequence: MTITKNKISLMLSSKLGFSNNLCEAIVNTVFSNILEIAKVQKLTLKNFGSFEVKQKTPRPGINFHTKSPVMIASKKNLRFTPSEKLKALINKSML
What are the official names of this protein?
Histone-like DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RIMO_NOSS1
Sequence: MGEKPTIAISHLGCEKNRIDTEHMLGLLVKAGYGVDTNEELADYVIVNTCSFIESAREESVRTLVELAEANKKIVITGCMAQHFQTQLLEELPEAVAVVGTGDYHKIVSVIERAEQGERVTLVSAEPTYIADETTPRYRTTTEGVAYLRVAEGCDYRCAFCIIPHLRGNQRSRTIESIVAEAEQLVAQGVQEIILISQITTNYGLDIYGKPKLAELLRALGKINVPWIRMHYAYPTGLTPDVIAAIQETPNVLPYLDLPLQHSHSEVLRSMNRPWQGRVNDEIIERLKIAIPGAVLRTTFIVGFPGETEAQFEHLLQFVQRHEFDHVGVFTFSAEEGTPAYKLPNQLPQEVMDERRDRLMALQQPISWRKNQQEVGKTVEVLIEQENPESGKLIGRSGRFSPEVDGQVYVDGEAKLGTIIPVKIHSADEYDLFGQVVSHN
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCS1F_CAMCR
Sequence: MELATTGKVNEVLFMNRGEGESSYAQNSSFTQQVASMATLALENAVETLFSKDFHLQALNATDLGCAAGPNTFAVISTIKRMMEKKCRELNCQTLELQVYLNDLFGNDFNTLFKGLSSEVIGNKCEEVPCYVMGVPGSFHGRLFPRNSLHLVHSSYSVHWLTQAPKGLTNREGLALNKGKIYISKTSPPIVREAYLSQFHEDFTMFLNARSQEVVPNGCMVLILRGRQSSDPSDMQSCFTWELLAIAIAELVSQGLIDEDKLDTFNIPCYFPSLEEVKDIVERDGSFTIDHMEGFELDSLQMQENDKWVRGENFTKVVRAFTEPIISNQFGHEIMDKLYDKFTHIVVSDLEAKLPKTTSIILVLSKIDG
What is the function of this protein?
Involved in the biosynthesis of caffeine (PubMed:26773541).  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of theobromine to caffeine (PubMed:26773541).
What are the official names of this protein?
Caffeine synthase 1, TCS1f.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: RR7_LILSU
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTETNPLSVLRQAIRGVTPNIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGGGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPSD_PVXCP
Sequence: MTTPANTTQAVGSTKSTTTTTAGATPANSGLFTIPDGDFFSTAKAVVASNAVATNEDLAKIQEIWKDKKIPSDTMAQAAWDLVRHCADVGSSAQTEMIGTGPYSNGVSRARLAAAIKEVCTLRQFCKKYAPVVWNWMLTNNSPPANWQAQGFKPEHKFAAFDFFDGVTNPAAITPKEGLMRPPSEAEMNAAQTAAFVKITKARAQSNDFASLDAAVTRGRITGTTVAEAVVSLPPP
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA.
What are the official names of this protein?
Coat protein, Capsid protein, CP.
What is the protein family that this protein belongs to?
Belongs to the potexvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: GME61_PESMI
Sequence: MVSAKKTVLITGCSEGGMGAALAVAFKEAGFRVYATARDPSKMASLSRAGIETLTLDILSSESIATCASSVSSLDILVNNAGSSYSMPVADMDINYAKQLFDVNVWAQLAVSQAFLPHLIKSKGMISAYNASKAAISMFSDCQRLELEPFGVKVIDLKTGAVASNLIKNQKTLTPITLPRDSIYEPARDAVEAAMRNDKMADVGTPANQWAKEVVGDLTRKSPPLVIWRGANAKLGRFGTIMPHGMMDSTIKKMTGLDVVEQKVRVA
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of dibenzodioxocinones such as pestalotiollide B, a novel class of inhibitors against cholesterol ester transfer protein (CEPT) (PubMed:31474098).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS pks8/GME11356.  Pks8/GME11356 lacks a thioesterase (TE) domain, which is important to the cyclizing of the third ring of atrochrysone carboxylic acid, and the esterase GME11355 might play the role of TE and catalyzes the cyclization reaction of the C ring.  The lactamase-like protein GME11357 (or other beta-lactamases in Pestalotiopsis microspora) probably hydrolyzes the thioester bond between the ACP of pks8/GME11356 and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrates to form endocrocin anthrone.  Endocrocin anthrone is further converted to emodin via the endocrocin intermediate.  Emodin is then oxidized by several enzymes such as the Baeyer-Villiger oxidase GME11358, the oxidoreductase GME11367, the short chain dehydrogenase/reductase GME11373, as well as by other oxidoreductases from the cluster, to modify the A and C rings and open the B ring, and finally yield monodictyphenone.  The prenyltransferase GME11375 may catalyze the addition reaction between the C5 side chains and the carbon bone of dibenzodioxocinones.  The remaining biochemical reactions to the final product dibenzodioxocinones should be methylation catalyzed by methyltransferase GME11366 and reduction and lactonization reaction catalyzed by a series of oxidordeuctases (Probable).
What are the official names of this protein?
Short-chain dehydrogenase/reductase GME11361, Dibenzodioxocinones biosynthesis cluster protein GME11361.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.