PharMolix/UniProtQA huggingface dataset:
Protein: NUOG_PSEAE
Sequence: MATIHVDGKTLEVDGADNLLQACLSLGLDIPYFCWHPALGSVGACRQCAVKQYTDENDKRGRLVMSCMTPATDNTWISIEDEEAKQFRASVVEWLMTNHPHDCPVCEEGGHCHLQDMTVMTGHNERRYRFTKRTHQNQELGPFIAHEMNRCIACYRCVRYYKDYAGGTDLGVYGAHDNVYFGRVEDGVLESEFSGNLTEVCPTGVFTDKTHSERYNRKWDMQFAPSICHGCSSGCNISPGERYGEIRRIENRYNGSVNHYFLCDRGRFGYGYVNREDRPRQPLLVLSKQKLSLDGALDQAAALLKERKVVGIGSPRASLESNFALRELVGEGNFYSGINEGELDRLRLILQVMQEGPLPVPSIRDIEDHDAVFVLGEDLTQTAARIALALRQSVKGKAVEMAADMKVQPWLDAAVKNIAQHAQNPLFIASVSATRLDDVAEETVHAAPDDLARLGFAVAHAIDPSAPSVADLDPQAQAFAQRITDALLAAKRPLVVSGNSLGNKALIEAAANIAKALKQREKNGSISLVVGEANSLGLALFGGDSVEAALERLTSGQADAVVVLENDLYRRTDAARVDAALAAAKVVIVADHQQTATTAKAHLVLPAASFAEGDGTLVSQEGRAQRFFQVFDPTYYDARNMVREGWRWLHAIHSTLQGKRVDWTQLDHVTEAVAEAKPILAGIRDAAPAASFRIKGLKLAREPHRYSGRTAMRANISVHEPRTPQDIDSAFAFSMEGYSGSQEDRQQIPFAWSPGWNSPQAWNKFQDEVGGHLRAGDPGVRLIEPKGEGLDWFQAVPVPFSAKADSWKVVPLYHLFGSEENSSRAAPIQQRIPETYVALSKEDADRLGVNDGATLGFQLKGQALRLPLRIDEQLGAGLIGLPVGFAGIPAAIAGCSVEGLQEAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: SID1_CAEEL
Sequence: MIRVYLIILMHLVIGLTQNNSTTPSPIITSSNSSVLVFEISSKMKMIEKKLEANTVHVLRLELDQSFILDLTKVAAEIVDSSKYSKEDGVILEVTVSNGRDSFLLKLPTVYPNLKLYTDGKLLNPLVEQDFGAHRKRHRIGDPHFHQNLIVTVQSRLNADIDYRLHVTHLDRAQYDFLKFKTGQTTKTLSNQKLTFVKPIGFFLNCSEQNISQFHVTLYSEDDICANLITVPANESIYDRSVISDKTHNRRVLSFTKRADIFFTETEISMFKSFRIFVFIAPDDSGCSTNTSRKSFNEKKKISFEFKKLENQSYAVPTALMMIFLTTPCLLFLPIVINIIKNSRKLAPSQSNLISFSPVPSEQRDMDLSHDEQQNTSSELENNGEIPAAENQIVEEITAENQETSVEEGNREIQVKIPLKQDSLSLHGQMLQYPVAIILPVLMHTAIEFHKWTTSTMANRDEMCFHNHACARPLGELRAWNNIITNIGYTLYGAIFIVLSICRRGRHEYSHVFGTYECTLLDVTIGVFMVLQSIASATYHICPSDVAFQFDTPCIQVICGLLMVRQWFVRHESPSPAYTNILLVGVVSLNFLISAFSKTSYVRFIIAVIHVIVVGSICLAKERSLGSEKLKTRFFIMAFSMGNFAAIVMYLTLSAFHLNQIATYCFIINCIMYLMYYGCMKVLHSERITSKAKLCGALSLLAWAVAGFFFFQDDTDWTRSAAASRALNKPCLLLGFFGSHDLWHIFGALAGLFTFIFVSFVDDDLINTRKTSINIF
What is the function of this protein?
Plays a role in RNA-mediated gene silencing by acting cell-autonomously as a channel for the transport of double-stranded RNA (dsRNA) between cells.  Mediates the spread of dsRNA and subsequent silencing of genes in cells distant from the site of dsRNA introduction.  Selective for dsRNA.  Preferentially binds long dsRNA, from 50 base pairs up to 700.  Short 20 base-pair long molecules are not bound.  May also bind dsDNA, but with lower affinity.  Binding may be sequence-independent (PubMed:26067272).  Required for avoidance behavior induced by small RNAs derived from pathogenic bacteria such as P. aeruginosa (PubMed:32908307).
What are the official names of this protein?
Systemic RNA interference defective protein 1, Systemic RNAi enabling protein.
What is the protein family that this protein belongs to?
Belongs to the SID1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Enriched at the cell periphery and also to the punctate structures of cytoplasm.
Protein: SUFS_ECO55
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_ACIBT
Sequence: MARYIGPKCKLSRREGTDLQLKSGVKPFDVKTKKANKAPGQHGQARGGKQSEYSLQLREKQKVRRIYGVLERQFSNYYKEAARVKGATGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHRSITLNGRRVNIASIQVKAGDVIAVHEGAKQQLRIKNAIELAAQRGIPAWIEVDHSKLEGTFKAAPDRSDLPAEINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: UBP37_MOUSE
Sequence: MSPLKIYGPIRIRSMQTGITKWKEGSFEIVEKDNRVSLLVHYNTGGIPRVFQLSHNIKNVVLRPSGIKQSRLMLTLQDNSFLSIDKVPSKDAEEMRLFLDAVHQNRLHAAMKASQGSGSFGTILGSRTSQKETNRQLSYSDNQASSKRGSLETKDEIPFRKVLGSPGRGPIKTVTGGGMAVTRTIPSLTLTSTPLRSGLLENRTEKRKRMLSGSELTEDYPKENDSSSNNKAMTDPSRKYLTSCREKQLSLKQAEENRTSGLLPLQSSSFYGSRAGSKDYSSGVTNLDRCNVSSQTPSAKRSLGFLPQPTPLSVKKLRCNQDYAGWNRPRVPLSSHQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDLLKQSIPWKKIPFNALIRRFANLLIKKDICNSETKKELLKKVKNAISATAERFSGYVQNDAHEFLSQCLDQLKEDMEKLNKTWKTEPVLGEENLPDTSATKVFTCPVITNLEFEVQHSIICKACGETIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEELEYSCEKCGGKCALVRHKFNRLPRVLILHLKRYSFNVALSLNNKLGQQVIIPRFLTLASHCTESTKPPVTLGWSAPVAISRPLRACQMMNSCITSPSAPSKKFTFKSKSSVTSCLDSDSEDELKRSVVLSQRLCDLPGNEQYQEDVEKDLKLCRLEPGKAELENSGFDRMSEEEVLAAVLEISRREASPVLSPEDDDKPTSSPDTGFAEDDIPEMPENPDAMEIEKSKTITEPGPASFTEITKDCDENKENKTPEGSQGEVDWLQQYDVDREREEQELQQALAQSLQEQEAWEQKEDDDLKRATELSLQEFNNSFLDSLGSDEDSGNEDVFDMEYTEAEAEELKRNAETGALPHSYRLISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDRSGYIFFYMHKEIFDELLETEKTSQALSMEVGRAARQAS
What is the function of this protein?
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry.  Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex.  Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro.  Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2).  Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RL16_SHELP
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGEFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEELAREAFTLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: THIG_NEOYE
Sequence: MKQSFSRPHFENQELDSLKIGEKIFNSRLMVGTGKYNNLKEAIKSIDYSGANIVTVAIRRAQNSKNLGRSNLLDGLDWSKLWILPNTAGCESAEEAVRIAALGREIVKKLGQTDNNFIKLEVIPDSHYLFPDPIGTLKAAEYLVKKGFIVMPYIGADPVLAKQLENIGCATVMPLASPIGSGQGLKNLLNLKIIIENSNIPVIIDAGIGTPSEAAKVMEMGASGVLVNTAIARAPNSPQMAKAMSLAVKSGRLTHTAGRMIINQTANPSSPIFGISK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TAL_EDWI9
Sequence: MTDKLTSLRQLTTVVADTGDIAAMKQYQPQDATTNPSLILNAAQIPEYRKLIDDAIAWARAQSGDRAQQIVDASDKLAVNIGLEILKLIPGRISTEVDARLSYDTEASVAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAERLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWHKANGGKSEFAPAEDPGVISVTEIYNYYKQHGYETVVMGASFRNVGEILELAGCDRLTISPPLLKELSESTGNVERKLADQGEIKARPARMSEAEFYWQHNQDPMAVEKLADGIRKFAVDQGKLESMIGALL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_LEPIN
Sequence: MNQSKEVRTRFAPSPSGFLHVGGARTALFNYLYAKSQGGKFILRIEDTDQNRSTEDSFKIILESLKWLGVNWDEGPEVGGEYGPYIQSQRLNIYKEYTEKLLKEKKAYRCFCTQEELEAKKKQSEAMGVPYVYDGLHANMSDEEVQEKLKQGIPYSVRFKTPSKTLIINDIIQGKVKFETKLIGDFIIVKSDGFPSYNYAVVVDDALMKITHVIRGVGHLSNTPRQILLYEALGYNIPEFAHASEIVGMDGKKLSKRAGATSILAFRDLGYLPETFRNYMALLGWTSTDGREFLPGDELEKIFDVHRCSKSPSTFDVFKKPKGSDEEVVTNFSDLTQIAEAMNPKSKLNWLSNRTIRDLNISKVLENLLPFLMDRKDIPAEVKNVNNPILTSIVESVRVYLDNLTQAPDYVAEFFVTDLKIQSEETIGFLKDGEGPKVVNEFYEILKNSDPKTDEDYKNLMSKVGEVTGQKGKTLYMPIRAATTGKSAGLELPILFPLLGKEKLLQRIEKTSKETGISLSN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREC_ASPFN
Sequence: MAQGPSCASELHYYRALDHANAGFATGTYHLKDDLHLATPPPHPSEAPVVNPNPLATVPTPPTSGVKLSLVSVGQRNKLPVFTSKEKVTAPPFADGNPALAAIPTKDGLKRRKPKNNIIKSSSSFVSRVITHEASSKRLNDRNPDGLFAFANINRAFQWLDLSSKNKEEPLAKILFTKAHMLTHDINELTKSSSHIDIAMGSSAGDIIWYEPISQKYARINKNGVVSNSPVTHIKWIPGSENMFMAAHANGQLVVYDKEKEDALFTPEISNHSAEAMKASSRLPLQVLKSVNSRNQKTNPVALWKLANQKISQFAFSPDQRHLAVVLEDGSLRVMDYLKEEVLDIFRSYYGGLICVCWSPDGKYIVTGGQDDLVTIWSFPERKIVARCQGHNSWVSTVAFDPWRCDERTYRFGSVGDDCRLLLWDFSVGMLHRPRAHQASARQRTSMIASNTQHFNRHRADSASNRMRSDSQRTADTYNDYDSAVRHPVEPRARTALLPPIMSKIVGDDPICWLGFQEDSIMTSSLEGHIRTWDRPREGINDSYNGNTSSPAISTSAAGSGSGIADSAMGSL
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression.  CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
What are the official names of this protein?
Probable catabolite repression protein creC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat creC family.
Protein: KATG_BEII9
Sequence: MDAQTDDKAQGKCPFVHAEHGRTNRDWWPKQPNLQILHQNSSLSNPMGEAFDYAKEFKSLDLNAVIADLKALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRIGDGRGGAGGGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRKISWADLMILTGNVALESMGFKTFGFAGGRIDTWEPDQSAYWGAETTWLALSNDPNNKHSRYSGDRDLENPLAAVQMGLIYVNPEGPDGNPDPLAAARDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPADHVGSEPEAAAVEQQGLGWKSSFGTGVGKDAITSGLEVIWTQTPIQWSNHYLENLFGFEWELTKSPAGAHQWRPKNGAGAGSVPDAFDPNKRHAPSMLTTDLALRADPAYEKIARRYLENPAEFADAFARAWFKLTHRDMGPRARYLGPLVPEEELIWQDPVPAVDHPLVDEADVVALKEKILSSGLTVAELVSTAWASASTFRGSDKRGGANGARILLAPQKDWAVNEPQKLDKVLKALEVIQADFNAALSGGKKISLADLIILAGGAAIEKAASEAGQKITVPFAPGRTDASQEQTDVHSFAPLEPPADGFRNDVPAKLAEISGHLLVDRAQLLTLTAPEMTVLIGGLRVLGANTGGSKHGVFTTRPGVLSNDFFTNLLDMGTEWKPAAEDGVYEGHDRKTKAVKWTATRVDLLFGSHAQLRALAEVYGCADAQTKFVTDFVAAWTKVMNADRFDLI
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NUSB_CHLL3
Sequence: MKTYRRQIREKILQALYTLELRETDIESAAGWLLTPEILEDPNAMKFFNLLLKSIKDNREEIDRYIAAHTFNWDMSRIAIIDKNILRMALAELLYCEDIPPKVSINEAIEIAKKFNSTDKSSKFVNGILDAIFNELKTEGKIKKNGRGLINHSPAKVQKTEPE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: THSA_HALSA
Sequence: MAQQMGNQPLIVLSEDSQRTSGEDAQSMNITAGKAVAESVRTTLGPKGMDKMLVDSSGEVVVTNDGVTILKEMDIEHPAANMIVEVAETQETEVGDGTTTSVVVSGELLSEAETLLEQDIHATTLAQGYRQAAEKAKELLDDAAIDVSADDTETLEKIAATAMTGKGAENAKGVLSDLVVRAVQSVADDNDVDTDNVKVEKVTGGAIENSELIEGVIVDKERVSENMPYAVEDANIALVDDGLEVQETEIDTEVNVTDPDQLQNFLDQEEEQLKEMVDALKDAGANVVFADSGIDDMAQHYLAKEGILAVRRAKSDDFTRLSRATGATPVSNVNDIEAADLGAAGSVAQKDIGGDERIFVEDVEEAKSVTLILRGGTEHVVDEVERAIEDSLGVVRVTLEDGQVMPGGGAPETELAMQLRDFADSVGGREQLAVEAFADALEVIPRTLAENAGHDPIDSLVDLRSQHDGGDTEAGLDAYNGDVIDMESEGIVEPLRVKTQAIESATEAATMILRIDDVIAAGDLAGGQVGDDDGDDGPAGGPGGMGGGMGGMGGMGGMGGAM
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: PSBN_CERJA
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RR4_TRARA
Sequence: MSRYRGPRLKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKKSTGQVLLQLLEMRLDNIVFRLGMASTIPGARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNSIASSDPGKLPKHLTVDTLQYKGLVQKILDRKWVGLKINELLVVEY
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ERC6L_BOVIN
Sequence: MEVSRGFAEAGALSPEQAASYLRYVKEAKEATKNGDLEQALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEHGDDEFIDVCNSGLLLYQELHNQLYEYQKEGIAFLYSLYRDGRRGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTSLISTWLREFVKWTPGMRVKTFHGPSKDERTRNLCRIQQRNGVIITTYQMLINNWQQLSSLNGQEFLWDYVILDEAHKIKSSSTKSAICARAIPASNRILLTGTPIQNNLQELWSLFDFACQGSLLGTLRTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEEVQKKKSSNPEVQLSEKSPDVGAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGAAKFSVQDEIEGEDSSDVDHIDQISDDTLMEESGKMLFLMDLLKKLRDEGHQTLVFSQSRRILNIIERLLKNRHFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYFSKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKNLDEHIAFLHSLRIAGISDHDLMYTRDLSVKEELDVIEDSHYIQQRVQKAQFLVESESQNTELLMERQKMGNEGIWLREPVYQTKKKRPKVNKPQPQPSSHLPVYHTQEEISSLMASIIIDDLPKEDEKDLSRIKLNDTIPQDGRHPCVITLNDDFVTTLPKGCGDVEEIFPDSLSGMALQKEASQEGFMQESEQESPLASFNYLPSKSARVDLGPNLDQLEDDEVLHHCNPSPANPKTKEYQRPESNVSVIKIADDDLTAAHSALQDAQANEAKLEEEPLASSGQYACDFNLFLEDSADNGQNLSSQFLEHVEKENSLCGSAANSRAESVHSKACLSVDLSEEDDEPEEVVNVKIRRKARRIDSDNEDEHTFKDTSSTNPFNTSPFPFLSVKQFDASTPKNDISLPERFFSPKISDSINKSVNSRRSLASRRSLINVVLDHVEDMEERLDNSSEAKVVEDHLEEGAEESGDEAPEHTKEDPSRETLSSENKSSQLSTSKPGALAQETSPGDPEPLSDGQLVDSPQDEAMEAVNDYDTLVLHGKELKECGKIQEALDCLVKALDIKSSDPEVMLMTLSLYKQLNKT
What is the function of this protein?
DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.  Functions as ATP-dependent DNA translocase.  Can promote Holliday junction branch migration (in vitro).
What are the official names of this protein?
DNA excision repair protein ERCC-6-like, ATP-dependent helicase ERCC6-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Chromosome. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.
Protein: Y997_ACTSZ
Sequence: MFGKGGLGGLMKQAQQMQERMQKMQDEIAQLEVTGESGAGLVKITLNGAHNCRRIEIDPSLMEEDKEMLEDLIAAAFNDAVRRAEEMQKEKMASVTAGMSLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Asuc_0997.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PDE7A_MOUSE
Sequence: MGITLIWCLALVLIKWITSKRRGAISYDSSDQTALYIRMLGDVRVRSRAGFETERRGSHPYIDFRIFHSQSDIEASVSARNIRRLLSFQRYLRSSRVFRGATVCSSLDILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSEDANAAFELNSQLLTQENRLS
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:11027622).  May have a role in muscle signal transduction (By similarity).
What are the official names of this protein?
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, P2A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: 1433T_CHICK
Sequence: MDKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKMQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein theta.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CANA_CANEN
Sequence: MAFSARFPLWLLLGVVLLASVSASFAHSGHSGGEAEDESEESRAQNNPYLFRSNKFLTLFKNQHGSLRLLQRFNEDTEKLENLRDYRVLEYCSKPNTLLLPHHSDSDLLVLVLEGQAILVLVNPDGRDTYKLDQGDAIKIQAGTPFYLINPDNNQNLRILKFAITFRRPGTVEDFFLSSTKRLPSYLSAFSKNFLEASYDSPYDEIEQTLLQEEQEGVIVKMPKDQIQEISKHAQSSSRKTLSSQDKPFNLRSRDPIYSNNYGKLYEITPEKNSQLRDLDILLNCLQMNEGALFVPHYNSRATVILVANEGRAEVELVGLEQQQQQGLESMQLRRYAATLSEGDIIVIPSSFPVALKAASDLNMVGIGVNAENNERNFLAGHKENVIRQIPRQVSDLTFPGSGEEVEELLENQKESYFVDGQPRHIDAGGKARRAHLPNLFRTFY
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Canavalin.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
Protein: H2A1_SOLLC
Sequence: MDATKTTKGAGGRKGGPRKKSVTKSIKAGLQFPVGRIGRYLKKGRYAQRVGSGAPIYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHVLLAVRNDEELGKLLAGVTIASGGVLPNINPVLLPKKSAVAEEKSPKAKAGKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1, LeH2A-1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NFUA_BUCA5
Sequence: MINISKKAQEHFTSLLSNEPENTQIRVFIVNPGTPNAECGVAFCPENEIELSDIQLKYDGFFVYVNKDTISYLKNSVIDLVTDKIGSQLTLKAPYAKNNFSKKVSSSLEEKVKCFLNLEINPQLSMHGGRVELMKIDENGIAAIQFSGGCNGCSMIGSTLKETVEKKLLSSFSEIKKVYDETHHLHGQHSFY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: HSLV_RHILW
Sequence: MTTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRIGKGEVIAGFAGATADAFTLLERLEKKLEQYPGQLMRAAVELAKDWRTDKYLRNLEAMMLVADKSITLAITGNGDVLEPEHGTTAIGSGGNFAFAAARALMDTDKSAEEIARRALEIAADICVYTNHNIVVESLDVEG
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_GLAP5
Sequence: MQFSKMHGLGNDFMVIDGVTQNVYLTEELIRKWADRHRGVGFDQLLLVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKQDIGVSTAKGKMVLSLQDDGQVRVNMGEPIWEPAQIPFTANKFEKNYILRTDIQTVLCGVVSMGNPHCVLQVENIQTANVNELGALLERHERFPERANIGFMQVINRNHIKLRVFERGAGETQACGSGACGAVAVGIMQGLLDSRVQVDLPGGTLHIEWQGVGSPLYMTGDAEHIYDGAVKS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.