PharMolix/UniProtQA huggingface dataset:
Protein: NCBP2_ESOLU
Sequence: MPIKLNASFSDSYVDVSQYRDQHFKGNRYEQEKLLKQSNTLYVGNLSFYTTEEQVYELFSKSGDVKRIIIGLDKVKKTACGFCFVEYYTRADAENAMRFVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDPARGGYGKVVARP
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SYS_AQUAE
Sequence: MIDINLIREKPDYVKERLATRDKELVSLVDKVLELDKRRREIIKRLEALRSERNKLSKEIGKLKREGKDTTEIQNRVKELKEEIDRLEEELRKVEEELKNTLLWIPNLPHPSVPVGEDEKDNVEVRRWGEPRKFDFEPKPHWEIGERLGILDFKRGAKLSGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLYKCERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSAAKTYDIEVWFPSQNKYREISSCSNCEDFQARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILENYQQEDGSVVVPEVLRDYVGTDVIRPE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_VESOH
Sequence: MIYGVGVDIVNIERVERILSKNKEGFVKRVLSEYEQVLFAKKGDSSTYCAKRFSAKEAFAKALGIGIGKIVSFQDLTICNNKQGNPYFIFSAKLCLYLVDKNIKKAHLSLSDEKFNAMAFVILEIEN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PROM9
Sequence: MNILQNLKKSDPVISNFINSEKNRQETHLELIASENFASIAVMQAQGSVLTNKYAEGLPQKRYYGGCEFVDEIEELAIQRAKKLFNANWANVQPHSGAQANAAVFLSLLQPGDTIMGMDLSHGGHLTHGSPVNMSGKWFNAVHYGVNKETSELNFDEIREIALETKPKLIICGYSAYPRTIDFESFRNIADEVGAFLMADIAHIAGLVASKLHPNPLPYCDVVTTTTHKTLRGPRGGLILCKDGEFGKKFDKSVFPGTQGGPLEHIIAAKAVAFGEALQPDFVNYSQQVIKNAKVLASTLISRGIDIVSGGTDNHIVLLDLRSINMTGKIADLLVSAVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFNETAFAEVGEIIADRLLNPNDSVIESQCKDKVLALCNRFPLYEGKLEASIK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_PSEE4
Sequence: MHALQAKILDPRLGTEFPLPQYATPGSAGLDLRALLKEDTVLEPGQTLLIPTGLSVYIGDPGLAAMILPRSGLGHKHGVVLGNLVGLIDSDYQGELMVSCWNRGNTPFTITIGERIAQLILVPVVQAHFDIVEQFDETQRGTGGFGHSGTR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GLB1_LUMTE
Sequence: ECLVTEGLKVKLQWASAFGHAHQRVAFGLELWKGILREHPEIKAPFSRVRGDNIYSPQFGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERNLKPEFFDIFLKHLLHVLGDRLGTHFDFGAWHDCVDQIIDGIKDI
What are the official names of this protein?
Extracellular globin-1, Erythrocruorin, Globin D, Globin I.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PTND_ECOL6
Sequence: MSEMVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACGLLGL
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ManXYZ PTS system is involved in mannose transport.
What are the official names of this protein?
PTS system mannose-specific EIID component, EII-M-Man, EIID-Man, Mannose permease IID component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUC_PELUB
Sequence: MPLTLYDKIWNDHLVDQQDDGTALLFVDRHLVHEVTSPQAFEGLRNSNRKVRQPGLTLAVADHNVPTTDRSKGIADAESKIQVDTLESNCKEFGVQYLGMNDKRQGIVHIIGPEQGFTQPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLVQKKAKNFRINVNGKLPIGVTSKDVILQIIGQIGTAGGTGSVIEYAGSLISSLSVEQRMTICNMTIEGGARAGLIAPDEKIFEYLKGKPMSPKNENWDKAMKYWESLKTDDGAKFDKEINLVAEDILPMITWGTSPQDVITIDGKVPNPKNEQDEDKKNSLERSLNYMGLKADTLATDIKIDKVFIGSCTNGRIEDLREAAKILKDKKKASHVQAMVVPGSGLVKEQAEQEGLDKIFIASGFEWREPGCSMCLAMNADKLKPGERCASTSNRNFEGRQGRGGRTHLVSPGMAAAAAISGNLDDVRKYQN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL2_ALKOO
Sequence: MAIRKLKPTSPAKRQMTVSTFEEITTNQPEKSLLEPIKNSGGRNSYGRITVRHRGGAQKRHYRIIDFKRNKDGVPAKVATIEYDPNRSANIALLHYVDGEKRYIIAPQGLKVGDMVESGPNADIKTGNALPLANIPVGTMIHNIEMKPGKGAQLVRAAGNSAQLMAKEGKHALVRLPSTEVRYLPIDCKATIGQVGNQEHENITIGKAGRKRNMGIRPTVRGSAMNPNDHPHGGGEGRTSIGRPAPVTPWGKPALGYKTRDSKKASNKMIVSRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ATPG_CORJK
Sequence: MASLRELRTRIKSVNSTKKITKAQELIATSRITKAQARVDDAEPYADEITRVVQRLAAASTLDHKILQEPTDASRAAILVVSSDRGMCGGYNNNVFKKTAELRKRLENEGKDVVLYVSGNKGISYYNFRGEDIAGAWSGYSQDPDYAATHDVRRHLIDGFVAGSEGTAKWREGLKAEEGQAVQGFDEVHIVYTRFESMLSQKPEAHRLLPIETVVEEEKFELGEDLVSDKVDHIAADYDFEPDPDTLLKALLPQYVSRGIFAAMLESAASESAARRTAMSAATDNATDLVKQLSRVANQARQAQITQEITEIVGGASALADSGESD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y525_THESM
Sequence: MAEDIEEIRRKKLLELQKKLAEQKRAEEEQIRQEMELEAQLQAIMKQILTSEARERLTRVKLVRPELARQVELILVQLYQAGQITERITDEKLKRILAQIDARTRKEFRIKW
What are the official names of this protein?
DNA-binding protein TSIB_0525.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: DAPD_ACIAC
Sequence: MTQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQWIKKAVLLSFRLKDNELIEAGSLGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIAKGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHLSGGVGLGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSLPKGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_PSEPF
Sequence: MNNIAPVITIDGPSGSGKGTVAGILAKRLGWNLLDSGALYRLLAFAAHNHGVDLTNEELLKKLAAHLDVQFIAATDGQLQRIILEGDEVSDVIRTESVGSGASQVAALPAVREALLQRQRAFQEAPGLVADGRDMGTVVFPNAPLKIFLTASAEERARRRYLQLKGKVEGVSLSSLLDEIRARDERDTQRAVAPLKPAADAIQLDSTELSIDQVLERIMSEIAIRDIAG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SALSV
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: TL11_SPIOL
Sequence: FKGGGPYGQGVTRGQDLSGKDF
What are the official names of this protein?
Thylakoid lumenal 11 kDa protein, P11.
What is the protein family that this protein belongs to?
To A.thaliana At2g44920.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: XKDH_BACSU
Sequence: MSYRQMLIHRCDIYHEAAQAPSAGRFGIPADRLQPVISYPDTPDEQDVPCYFTEKTQQLIQEEPDQTVYHSFLVHFPLSADIRVNDKIIWENHKYILKLPKRIRHHHWEVVAVRDESL
What are the official names of this protein?
Phage-like element PBSX protein XkdH.
What is the protein family that this protein belongs to?
To B.subtilis YqbH.
Protein: HOKF_SHIFL
Sequence: MLTKYALVAVIVLCLTVLGFTLLAGDSLCEFTVKERNIEFRAVLAYEPKK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system (By similarity).  When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration (By similarity).  Its toxic effect is probably neutralized by an antisense antitoxin Sok RNA (By similarity).
What are the official names of this protein?
Putative protein HokF.
What is the protein family that this protein belongs to?
Belongs to the Hok/Gef family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS2_CERSK
Sequence: MDMALPEFSMRQLLEAGVHYGHQTARWNPKMAEFIYGDRNGIHIVDLTQTVPMLDQALKVVRDTVAKGGRILFVGTKRQAQKPIAEAAEKCAQHYMNHRWLGGTLTNWKTVSQSIQRLKQLDEVLATGAEGLTKKERLNMEREQQKLQASLGGIREMGGTPDLLFIIDVGKEDLAIAEAQKLGIPVVAVVDTNNSPKGVDYVIPGNDDAARAIALYCDLVSRAALDGMSAQMGAAGIDLGALDVAPEEETLEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS3_STRZP
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQKELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINIIEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL27_KOSOT
Sequence: MAHKRSSGAGRNGRDSNPKYLGVKRGENAFVRAGTIIIRQRGTKIHPGQNVGMGRDFTLYALIDGKVHFETRNNRKYVSVYAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: AT2_CROXC
Sequence: MSFTVTKTAPAVITPSEPTPSGHILPLSFFDRLPFLRVFLVDMIMVYGHGDQPAKVIKEAVAKALVHYYPLAGRLTTDTDDGELSVACTGEGVWFVEATADCRMEDVNYLQVEPLMIPKEQILPSHPEGVDPYTLPFMIQVTQFRCGGFTFATRANHAVFDGIGAGQIKVAIGEMARGLKHPTVKPVWCRDVIRKPIPSQISATEPHDTDLSSIPDLKFTNNQTNIECCSFDLSLDHINHLKDHFAKEVGKICSVFDVIAAKLWQSRTRAIGLQPQTEVSLTFLLNIRQVVLHNELPPDGGYYGNCLVPLINKAPSGQIANAPLFEIVRLIKEAKDDLLSKDSASLIGEMPPYKKPSYADLSIVDWRRLGLYEADFGWGGPMFLVPLNEHTVTSCSTYLFKSPVASKKDVRLVTYCIVKEHLEAFRDEMNDFT
What is the function of this protein?
Caffeoyltransferase involved in montbretin A (MbA) biosynthesis (PubMed:29967287).  Catalyzes the caffeoylation of myricetin 3-O-beta-D-glucosyl 1,2-alpha-L-rhamnoside (MRG) to produce myricetin 3-O-(6'-O-caffeoyl)-beta-D-glucosyl 1,2-alpha-L-rhamnoside (mini-MbA), a precursor of MbA (PubMed:29967287).  Mini-MbA and MbA are potent inhibitors of human pancreatic alpha-amylase and are being developed as drug candidates to treat type-2 diabetes (PubMed:29967287).  In vitro, is able to catalyze the caffeoylation of quercetin 3-O-sophoroside (QGG), although QGG may not be a physiological substrate in vivo (PubMed:29967287).  In vitro, can use coumaryl-CoA, feruloyl-CoA and acetyl-CoA, although these three acyl donors may not be physiological in vivo (PubMed:29967287).
What are the official names of this protein?
Myricetin 3-O-glucosyl 1,2-rhamnoside 6'-O-caffeoyltransferase AT2, Acyltransferase 2, CcAT2.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: HISX_HALH5
Sequence: MKIVTINDSVSLKRDLDTGTDMQQNAVHSIIAQVREQGDQALFTLTKQFDGADLTTLRVQQAEIEAAYREMEEPVLQAIGEAIENIRDFHERQKRNSWMTTKSDGTILGQKITPLDSVGLYVPGGKAAYPSSIMMNVIPAQVAGVQNIVIVSPPQKDGSIPAGVLVTAAELGVKTILKVGGAQAIAALAYGTESVPAVDKITGPGNIYVALAKRAVFGHVDIDMIAGPSEIVVLADERANPRYIAADLLSQAEHDERASAILVTPSRALAEEVAVEVDQQLTTLPKREIAAASIRDYGAIYVTETLEEAVSVVNELAPEHLEILAEEPMSFLGKIRHAGAIFLGPYSSEPVGDYFAGPNHVLPTNGTARFSSPLNVDDFVKKSSIISYSKAALLENGAKISALARLEGLEAHARAIDIRLEDER
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: HIS6_THEON
Sequence: MLAKRIIAALDIKEGRVVKGIKFQNIRDAGDPIELARRYEEEGIDEIVFLDITASFEKRKILLDLVKRIAEEIYVPFTVGGGIKSVEEIREIIKSGADKVFLNTAAVNNPELVREAAKVVGSANLVIAIDAKWNGEYWEVYTHGGRKARGINAVEWAKEVERLGAGEILLTSMDTDGTQEGFDIPLTKAIVEAVDIPVIASGGAGSPEHFYEAFKIGAEAALAASIFHYGKYTVRELKEYLAEKGIPVRLNY
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPN_BACCR
Sequence: MGNPKKNSKDFAPNHIGTQSKKAGGNKGKQMQDQTGKQPIVDNG
What are the official names of this protein?
Small, acid-soluble spore protein N, SASP N.
What is the protein family that this protein belongs to?
Belongs to the SspN family.
What are the subcellular locations of this protein?
Spore core.
Protein: ACSA_CUPTR
Sequence: MSAIESVMQEHRVFNPPEAFASQAAIPSMDAYRALCDEAERDYEGFWARYARELLHWNKPFTKVLDESNAPFYKWFEDGELNASYNCLDRNLQNGNADKVAIVFEADDGTVTRVTYRELHAKVCRLANGLKTLGIRKGDRVVIYMPMSVEGVAAMQACARLGATHSVVFGGFSAKSLQERLVDVGAVALITADEQMRGGKALPLKAIADDALALGGCEAVKNVIVYRRTGGNVGWTEGRDRWLDDVCANQPDTCEAEPVGAEHPLFVLYTSGSTGKPKGVQHSTGGYLLWALMTMKWTFDIKPDDLFWCTADIGWVTGHTYIAYGPLAAGATQVVFEGVPTYPNAGRFWDMIARHKVSIFYTAPTAIRSLIKAAEADEKIHPKQYDLSSLRLLGTVGEPINPEAWMWYYKNVGNENCPIVDTFWQTETGGHMITPLPGATPLVPGSCTLPLPGIMAAIVDETGHDVPNGSGGILVVKRPWPAMIRTIWGDPERFKKSYFPEELGGKLYLAGDGSIRDKDTGYFTIMGRIDDVLNVSGHRMGTMEIESALVANPLVAEAAVVGRPDDMTGEAICAFVVLKRSRPSGEEAAKLATELRNWVGKEIGPIAKPKDIRFGDNLPKTRSGKIMRRLLRSLAKGEEITQDTSTLENPAILEQLKQAQ
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PCKG_MYCVP
Sequence: MTAATIPGLDNAPTKHQGLLEWVREVAELTQPDRVAWADGSQEEYDRLCAQLVEAGTFKKLNPEKQPNSYLALSDPSDVARVESRTFICSKREIDAGPTNNWMDPAEMRGILTDLYRGCMRGRTLWVVPFCMGPLDADDPKLGVEITDSEYVVVSMRTMTRMGAAALQKMGDDGFFVKALHSIGAPLEPGQKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWMRFGKDGRLYATNPEFGFFGVAPGTNWDSNPNAMKTIAAGNTVFTNVALTDDHDVWWEGLEGEPDHLIDWKGQDWILRETETKAAHPNSRYCTPISQCPTLAPEWDDPQGVPISAILFGGRRKTTVPLITEARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQHWINIGKQADESQLPKVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGKSTPIGIVPTAADLDLEGLDVDPADVDEALAVNADEWRAEVPLIEEWFEFVGEKLPTGIKDEFDALKTRLAEDS
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KARG_METEN
Sequence: MADAAVIEKLEAGFKKLEAATDCKSLLKKYLTKEVFDKLKDKKTSLGATLLDVIQSGVENLDSGVGIYAPDAEAYTLFAPLFDPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPEGKFVISTRVRCGRSMQGYPFNPCLTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHFLFKEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRLTSAVNEIEKRIPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMI
What is the function of this protein?
Catalyzes the reversible transfer of high energy ATP gamma-phosphate group to L-arginine.
What are the official names of this protein?
Arginine kinase Met e 2, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: COAE_JANSC
Sequence: MSFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKDGAIDRAVLRAAIADDASLLKQIEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGDAACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPDAEKRARATYVIETDTLDGTRQDVAHLVSKLTEGT
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_LEPIN
Sequence: MASSTFFSDWNQMLKPRVTSLVLATIIPGLYLASEQSPSGFLIAITLFGTFLMSSASFIFNQVIEKDRDAKMKRTSNRPIPSGRISVVQATLVGIAMMGSSFYVLAVYVNLLTALCAFAALISYVFLYTIFLKPRTTQNIVIGGVAGCVGPLIGYAAIGNSLPVQAWSLFMMIFLWTPAHFWALAIFLKEEYSDADFPMLPVVKGIHQTTKSIFFYTILYSIACVSFYFLESSMGFLYLIVSLIVCIWMGILSYQLIQNPEPQSARKFFFFSILHLFIINITIVVDHLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTPPA_PECAS
Sequence: MTQLYLASASPRRRELLTQLDIPFSVLNVAVKEQRLPEEAAEVYVRRLAHEKATAGVAAAPSDLPVLGADTIVVLNGQVLEKPQDETHAAEMLGQLSGKQHQVMTAVALADKDDILSCLVITDVVFRPLSQQDIERYIASGEPMDKAGAYGIQGKGGCFVRSLNGSYYAVVGLPLVETDELFSNFAALRSARGKHDC
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.