PharMolix/UniProtQA huggingface dataset:
Protein: SDPB_BACSU
Sequence: MKILNSLEGYIDTYNPWKNTYALFRSLLGFSTLLVLLFNSTDILFSYSANNVTCENVYIPTAFCFAKEYSINFEIIRYLMIFILTLVVIGWRPRFTGLFHWYICYSIQTSALTIDGGEQIATVLSFLILPVTLLDSRRNHWNIKKNNNESFTKKTVLFYIMTIIKIQVFIIYLNAALERLKNKEWAEGTAIYYFFSDPVFGLPEYQLNLMNPLLESNFIVVITWLVTIFELFLAASIISNIRIKRIALVLGILFHIGIIFSIGIVSFGLIMISALIIYLHPVQQNITMNWCSPLFKYIYVKGKRNFKRIGGESVKFLTKLFHS
What is the function of this protein?
Required for the maturation of SdpC to SDP (PubMed:12817086).  Not required for SdpC signal peptide cleavage, secretion from the cell or disulfide bond formation (PubMed:23687264).
What are the official names of this protein?
Sporulation-delaying protein SdpB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FRS2_HUMAN
Sequence: MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM
What is the function of this protein?
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways.  Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1.  Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
What are the official names of this protein?
Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1.
What are the subcellular locations of this protein?
Endomembrane system. Note=Cytoplasmic, membrane- bound.
Protein: Y850_MYCGI
Sequence: MASPDDPEDYQDRAAPAAHRVRAGTMLLANTDLLEPTFRRSVIYVVEHNDGGTLGVVLNRASETAVYNVLPQWAKLAVKPKTMFIGGPVKRDAALCLGTLRVGSDPVGVPGLRHVQGRIVMVDLDADPDELAPILEGVRIFAGYSGWTIGQLEGEIERDDWIVLSALPTDVLVEPKVDLWARILRRQPMPLSLLATHPIDLSRN
What are the official names of this protein?
UPF0301 protein Mflv_0850.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RM35_YEAST
Sequence: MLRRSIHTTKILQKPNATSHIWSDFTTRPSSLSIQSSKVKNYLFQKKASLDPPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYELANKTKNPLKKDALLIKAEINNPEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWIEPGEFLSSNVTSMRPIFKIQEYELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNIIADYLPPVPEKNAGKQRFVVWVFRQPLIEDKQGPNMLEIDRKELSRDDFDIRQFTKKYNLTAIGAHIWRSEWDAKVAAVREKYGLPPGRVFSRVRR
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L35, mitochondrial, Mitochondrial large ribosomal subunit protein mL38, YmL35.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily.
Protein: SPB7_HUMAN
Sequence: MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRYNGGINMYVLLPENDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSGKVSCP
What is the function of this protein?
Might function as an inhibitor of Lys-specific proteases.  Might influence the maturation of megakaryocytes via its action as a serpin.
What are the official names of this protein?
Serpin B7, Megsin, TP55.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR12_SYLSP
Sequence: MFTMKKSLLLIFFLGTINLSLCEEERNADEDEKRDGDDESDVEVQKRFMGTALKIAANVLPAAFCKIFKKC
What is the function of this protein?
Antimicrobial peptide.  Active against a variety of Gram-negative and Gram-positive bacterial strains.  Active against fungus C. glabrata 090902 and C. albicans ATCC 10231.  Shows hemolytic activity against human erythrocytes.
What are the official names of this protein?
Brevinin-1SN2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RS10_BURO0
Sequence: MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LARD_LACPL
Sequence: MVHQLIAEFMGTALMIIFGVGVHCSSVLKGTKYRGSGHIFAITTWGFGISVALFIFGNVCINPAMVLAQCLLGNIAWSLFIPYSVAEVLGGVVGSVIVWIMYADHFKASTDEISPITIRNLFCTAPAVRNLPRNFFVELFDTFIFISGILAISEIKTPGIVPIGVGLLVWAIGMGLGGPTGFAMNLARDMGPRIAHAILPIANKADSDWQYGIIVPGIAPFVGAAIAAWFMHGFFGIN
What is the function of this protein?
Transporter that facilitates the transmembrane diffusion of D/L-lactic acid.  Is involved in the cellular racemization of lactate and lactate metabolism.  The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes.  Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone.
What are the official names of this protein?
D/L-lactic acid transporter, Lactate racemization operon protein LarD, Lactic acid channel.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOB_SHIB3
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PP425_ARATH
Sequence: MNPTQTLFSPGGNSPASSPASHPSSLFPQINNCRTIRDLSQIHAVFIKSGQMRDTLAAAEILRFCATSDLHHRDLDYAHKIFNQMPQRNCFSWNTIIRGFSESDEDKALIAITLFYEMMSDEFVEPNRFTFPSVLKACAKTGKIQEGKQIHGLALKYGFGGDEFVMSNLVRMYVMCGFMKDARVLFYKNIIEKDMVVMTDRRKRDGEIVLWNVMIDGYMRLGDCKAARMLFDKMRQRSVVSWNTMISGYSLNGFFKDAVEVFREMKKGDIRPNYVTLVSVLPAISRLGSLELGEWLHLYAEDSGIRIDDVLGSALIDMYSKCGIIEKAIHVFERLPRENVITWSAMINGFAIHGQAGDAIDCFCKMRQAGVRPSDVAYINLLTACSHGGLVEEGRRYFSQMVSVDGLEPRIEHYGCMVDLLGRSGLLDEAEEFILNMPIKPDDVIWKALLGACRMQGNVEMGKRVANILMDMVPHDSGAYVALSNMYASQGNWSEVSEMRLRMKEKDIRKDPGCSLIDIDGVLHEFVVEDDSHPKAKEINSMLVEISDKLRLAGYRPITTQVLLNLEEEDKENVLHYHSEKIATAFGLISTSPGKPIRIVKNLRICEDCHSSIKLISKVYKRKITVRDRKRFHHFQDGSCSCMDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g48910.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: AP1_EMENI
Sequence: MADYNSLYQHGLYLSPDQQDLLLAALSSNNPPSKQKQNVQKPELGTNPTNTPGQASTGSFNTSPAFDGSHQFDNLNYDESPFLDFNPELEWDFPGSENLIGELPGSATSDDHEVGEKRKDSNSNGEVNGKKRRESDDKSDDKTSKKPGRKPLTSEPTSKRKAQNRAAQRAFRERKEKHLKDLEAKVEELQKASDSANQENGLLKAQVERLQVELREYRKRLSWVTQGNALSAINSYPGNANRMSGLNNNDFMFDFPKFGDLPGGRIFNGSVAKTNQNKKDDTPIPGILRHSALQAANGRASSSASPKTVTSNNPATKSPVTADGRLTSHTSSVYNYHQPGQGHDTSTSDSPSSSSDSHQFLSSSGTSPEPSVQSPDNQAKESHEGHTCTIDGEKSFCAQLGMACGNINNPIPAVRQRSESATNTPNAPSSTDNVPGIDFMAQQNGGQFDPLLFGDWREPQDAVLSQDFNTFFDDAFPLPDLGSPSHNLTEVGLGAQQKKSILEEMDNKEEEEVVPGEDKAQMLSCTKIWDRLQSMEKFRNGEIDVDNLCSELRTKARCSEGGVVVNQRDVDDIIGRV
What is the function of this protein?
Transcription activator involved in oxidative stress response, specifically during hyphal growth.  Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways including the mycelium-specific catalase catB (but not the conidia-specific catalase catA), thioredoxin reductase trxB and thioredoxin thiO (PubMed:17617701).  Preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3'.  Activity of the transcription factor is controlled through oxidation of specific cysteine residues resulting in the alteration of its subcellular location.  Activation by hydroperoxides induces nuclear accumulation and as a result NapA transcriptional activity (By similarity).
What are the official names of this protein?
AP-1-like transcription factor napA.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Oxidized napA is found predominantly in the nucleus, while reduced napA is continuously exported to the cytoplasm by CRM1/exportin 1.
Protein: RL32_FRACC
Sequence: MAVPKRRTSRSNTRSRRSQWKAKVPTLAKCSRGHVIRPHTVCGTCGRYNDRQVLDV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CET1_TOBAC
Sequence: MASRVVEPLVVARVIGEVVDSFNPSVKLNVIYNGSKQVFNGHELMPAVIAAKPRVEIGGEDMRSAYTLIMTDPDVPGPSDPYLREHLHWIVTDIPGSTDSSFGREIVSYESPKPVIGIHRYVLLLYKQSGRQTVKPAATRDHFNTRRYTAENGLGSPVAAVYFNAQRETAARRR
What is the function of this protein?
May form complexes with phosphorylated ligands by interfering with kinases and their effectors.
What are the official names of this protein?
CEN-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_XANAC
Sequence: MWFAAAPALGSGAAVVFGPPCGAVESEMDEQTLLKKLRWRCRRGMRELDQLFGRYLDQRWAQAPDAERAVFLQLLDCEDDKLWRWFMGYEACPDAANAALIADIRALPA
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_CHLT2
Sequence: MTETRRLRILITNDDGIKAKGISLLISLLREADFADLYVVAPLEEQSGRSMAFSLVEPTALEPFDYPQRVQEAWAVTGTPVDCVKLAIGELFKENALDLILSGINNGKNSGRCLYYSATVGAIREANLHGIPAIALSQSENIAFFQEAHMASLIRSLCEFTVAYKHTDPLGLNVNFPASADDSPWKGIRFTLSGNEFLFGIPRLVRTEGNRRYYTLYDMRDKVSEEFSEEYLALANNYISAAPLVSKNTPRATLSEEELAFLKDSFEQSVLWKASLNLEEDLA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKL1_LOCMI
Sequence: GPSGFYGVR
What is the function of this protein?
Myoactive peptide.  Stimulates the contraction of the oviduct and foregut.
What are the official names of this protein?
Locustatachykinin-1, Locustatachykinin I, TK-I.
What are the subcellular locations of this protein?
Secreted.
Protein: TLR2_PANPA
Sequence: MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYESKSLKSIQNVSHLILHMKQHILLLEIFVDVSSSVECLELRDTDLDTFRFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLIVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNVDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: AK1CL_MOUSE
Sequence: MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAAIFKGHPNWPFLDEY
What is the function of this protein?
NADP-dependent 17-alpha-hydroxysteroid dehydrogenase that converts 5-alpha-androstane-3,17-dione into androsterone.  Has lower 3-alpha-hydroxysteroid dehydrogenase activity.  Has broad substrate specificity and acts on various 17-alpha-hydroxysteroids, 17-ketosteroids, 3-alpha hydroxysteroids and 3-ketosteroids.  Reduction of keto groups is strictly stereoselective.  Reduction of 17-ketosteroids yields only 17-alpha-hydroxysteroids.  Likewise, reduction of 3-ketosteroids yields only 3-alpha-hydroxysteroids.
What are the official names of this protein?
Aldo-keto reductase family 1 member C21, 17-alpha-hydroxysteroid dehydrogenase, 17-alpha-HSD, 3(or 17)-alpha-hydroxysteroid dehydrogenase, 3-alpha-hydroxysteroid dehydrogenase, Dihydrodiol dehydrogenase type 1, DD1, Dihydrodiol dehydrogenase type 3, DD3.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP1_ARATH
Sequence: MADGHSFNNISLSGRGGKNPGLLKINSGGIQWKKQGGGKAVEVDRSDIVSVSWTKVTKSNQLGVKTKDGLYYKFVGFRDQDVPSLSSFFQSSYGKTPDEKQLSVSGRNWGEVDLHGNTLTFLVGSKQAFEVSLADVSQTQLQGKNDVTLEFHVDDTAGANEKDSLMEISFHIPNSNTQFVGDENRPPSQVFNDTIVAMADVSPGVEDAVVTFESIAILTPRGRYNVELHLSFLRLQGQANDFKIQYSSVVRLFLLPKSNQPHTFVVISLDPPIRKGQTMYPHIVMQFETDTVVESELSISDELMNTKFKDKLERSYKGLIHEVFTTVLRWLSGAKITKPGKFRSSQDGFAVKSSLKAEDGVLYPLEKGFFFLPKPPTLILHDEIDYVEFERHAAGGANMHYFDLLIRLKTDHEHLFRNIQRNEYHNLYTFISSKGLKIMNLGGAGTADGVAAVLGDNDDDDAVDPHLTRIRNQAADESDEEDEDFVMGEDDDGGSPTDDSGGDDSDASEGGVGEIKEKSIKKEPKKEASSSKGLPPKRKTVAADEGSSKRKKPKKKKDPNAPKRAMSGFMFFSQMERDNIKKEHPGIAFGEVGKVLGDKWRQMSADDKEPYEAKAQVDKQRYKDEISDYKNPQPMNVDSGNDSDSN
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  Binds specifically to double-stranded DNA (Probable).  Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed:16698901).
What are the official names of this protein?
FACT complex subunit SSRP1, Facilitates chromatin transcription complex subunit SSRP1, High mobility group B protein 8, Nucleosome/chromatin assembly factor group D 08, Nucleosome/chromatin assembly factor group D 8, Protein NUCLEAR FUSION DEFECTIVE 8, Recombination signal sequence recognition protein 1.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: PYLC_METAC
Sequence: MKTICLIGGKLQGFEAAYLSKKADMKVVVIDKNPQALIRNYADEFHCFDVIKEPEKLLEISKNVDAILPVNENLECIKFLSSVKEEFSCPVLFDFEAYRISRDKKKSKEYFRSIGIPTPQDKPGRPPYFVKPPCESSSVGARIIYDEEELGELEPGMLVEEYVEGEVISLEVIGDGTHFAVVKETLIHIDRTYDCHMVTPLPSDLSFREISYSLAANLPLKGIMDVEAISGPQGLKVIEIDSRFPSQTPTAVYYSSGVNLIELLFRAFGEGVEEVKTLPEDRYCIYEHLMLAENGALIPVGEQVLSMGNDYGKYYEEPGIEIFLCRGEDPVFTLVFWGKDREEAENKKRTGLLILKDRFGAAV
What is the function of this protein?
Is required for the biosynthesis of pyrrolysine (PubMed:17204561, PubMed:21455182).  Catalyzes the ATP-dependent ligation between (3R)-3-methyl-D-ornithine and L-lysine, leading to (3R)-3-methyl-D-ornithyl-N6-L-lysine (PubMed:21455182).
What are the official names of this protein?
3-methyl-D-ornithine--L-lysine ligase, (3R)-3-methyl-D-ornithine:L-lysine ligase, Pyrrolysine biosynthesis protein PylC.
What is the protein family that this protein belongs to?
Belongs to the PylC family.
Protein: FLHA_BORBU
Sequence: MLDARKNSILGYLGLNNKSDLIISVGLIFVVAGFILPLPAVILDVLITVNLVISLLIILIVLYSKRSLDFSVFPTLLLVMTIFGLVLNISSTRLILTKGINFDGQMIRTFGTFVVGSSGIQGLVIGFIIFIIIIAVQFIVITKGATRVAEVAARFALDALPGKQMAIDSAYSSGNLTEEEATRQKNDLQSEVNFYGAMDGASKFVSGNVKVGFLITLINILGGLLVGITLQGLNFNEALNNYVSLTVGDGLVSQLPSLLISTSTGLIVTRSISKNSFGGEIFDQFTNHLGIYWIVSGFLLFLAFLPGFPTLILMFLSLSIAFLAYSLSGIRQKEEIDKKMKLEEEQASIYSDKDVSPVVPLDPLALEIGYNLVPIVDDTKTSELLDRIVKIRREIAFEFGIVVPKIRIVDNMRLEPNAYSFKLRGVEVGRGEIKLGKFLVINVGIDSGIDGDLVKDPSFGLPSLWVNDDGRETAEKLGYTVVDPPSIIATHMTELIKRHSYEILTRQDVQNTLDVFKKDYGAIVEEVLKNFSVGEIQRVLQGLLKEQVSIRNLVTIFETIADFTSITKDIFFLIEKCRQSVGRQITSGYLDLNSELNVITLNPSFEQMIIDSRVESNHDLISSIDPNLKTKFIYELFKIVNEVQAEGFYPVVLSSESSRPIIKVITSREIPDLVVMSVLEVPQNIKVNVLKTVEVEE
What is the function of this protein?
Required for formation of the rod structure of the flagellar apparatus.  Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhA.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_LEPIC
Sequence: MATEAKYNRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIALVVGGGNIIRGTNLAKAGIDRATADYMGMLATIQNALALQDACEKKGLYTRVQSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLRAVEVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDSTALSLCMENNMSIIVFDIFKRGNLKDLVTGKNIGTLISNSEDIQIDGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDTA_ECOL6
Sequence: MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRHPLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQHVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSAAGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLAAKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPDAINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRSFYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of two 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Bifunctional Kdo transferase, Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: YBHG_SALPB
Sequence: MKKPVVIGLAIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDAIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ORF2_TTVI1
Sequence: MKEKDYWEEAWLTSCTSIHDHHCDCGSWRDHLWTLCALDDADLAAAADIIEREEADGGEDFGFVDGDPGDAGG
What are the official names of this protein?
Uncharacterized ORF2 protein.