PharMolix/UniProtQA huggingface dataset:
Protein: RNY_STAA1
Sequence: MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y, Conserved virulence factor A.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YGGU_SALPB
Sequence: MSAVTRCEDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLTKFLGKQFRVAKSQIVIEKGELGRHKQVKIIHPQQIPPEIAALTE
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: LBSA_EMENI
Sequence: MLLPTVRSRIAALSSRVASRAAYSTTVPRFTENAMQPNDPTPRPAKPNVSETDATPVDSMGAWDAALQESTDAAERVRTMQAPNRKGTWASNQKPRAEAMSGPRFEQTIMHLQPTPMAAIELIHKQPVRWVKDKIVSCDGGGGPLGHPRIFINTDKPEIVPCGYCGLPFAHEHHREYLKSLPTSSYPLEPTGAAEEVNENQRVTEGATGYEQR
What are the official names of this protein?
Lactobacillus shifted protein.
Protein: RBS2_WHEAT
Sequence: MAPAVMASSATTVAPFQGLKSTAGLPISCRSGSTGLSSVSNGGRIRCMQVWPIEGIKKFETLSYLPPLSTEALLKQVDYLIRSKWVPCLEFSKVGFVFREHNSSPGYYDGRYWTMWKLPMFGCTDATQVLNEVEEVKKEYPDAYVRVIGFDNMRQVQCVSFIAFRPPGCEESGKA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 2, RuBisCO small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PUR9_CLOPS
Sequence: MKKRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKTLEKREINTIDYVVVNLYPFFEKVRENLSFEEKVEFIDIGGPTMLRAAAKNFKDVVVLSDKKDYEKVMNEIKENNCVSFKLRKTLAGKVFNLMSAYDAAISNFLLEGEEEYPEYLSVSYKKIQDLRYGENPHQGAAYYSSTEFDGAMNSFEILNGKALSYNNIKDLDIAWKVACEFEETACCALKHNTPCGVAVGENSKEVYLKAYDADPVSIFGGIVAINRKIDKATAEEMVKIFLEVVAAPDFDEDALEVLRTKKNLRVIKCKNTPQAKNYMVTVDGGILVQGEDNKLANEYKVVTKKEPTEMELRDMIFGMKVVKYVKSNAIVVVKDGVATGIGGGQVNRIWATKEALERGKGGAVLASDAFFPFRDCVDEAAKNGIKAIIQPGGSIRDEESVEACNEHGISMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: P9_RDVO
Sequence: MGKLQDGIAIKRINDAITTFKNYKLDELEQGGSMAINTLSNVRAHVGLAWPAILRNCLIHTSSHLGFMKFMIDIATTWKVGAFTLLGSVGDEDPFTDVDLIYTKTCLHLGLKDNDFLQFPEEFAYEANSFLEAQSMNARVDMLTGVHNIEDKYVFRMQSISKFLKAYYTASEDVAYLTGFIKPDDSKDSILSAELLKAQVTSEVLRVRNLITTKIQKYINLYEDSQLPHFRQAALSYTQDWDVDGGVPAALPQPDITDDESPVTNPGPSAPPVSKGADQPEDEEMIRKKVETSKDAPPKAVPSGNVSARGIPAFLEDDMSEMDAPDGFHDYLTREHENNFDLAQLGLAPSV
What is the function of this protein?
Minor outer capsid protein.
What are the official names of this protein?
Minor outer capsid protein P9.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus minor outer capsid protein P9 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Found in the peripheral regions of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: UXAC_CALS8
Sequence: MKRFMDEDFLLNNQTAKVLYEKYAKDMPIIDFHCHLNPKEIYENKKFRNITEVWLGGDHYKWRLMRANGIEEKYITGSADDYEKFLAWAKTIPMAIGNPIYHWTHLELKRYFGIDEILNEKSAPIIWEKANKVLEELGARDIILKSNVEVICTTDDPVDTLEYHLKLKDDKNFNVKVYPTFRPDKGVNIERETFIPWVEKLGEVYGKKIESYDEFLDALKSRAEFFHSVGCRASDHAIDNMVFAEASFDEVANIFKKALAGEKLTEIEVAKYKTYTLRFLGKVYSSLGWAMQLHINALRNNNTRMFNILGPDTGYDSINDGHIALALVKFLDSLEKENSLPKTILYSLNPKDNYVLATIMGSFQDGSIPGKMQLGAAWWFNDSKDGNLQQMKDLANLGLLSRFVGMVTDSRSFLSYARHEYFRRLLCKLIGEWVENGEYPYDLEALSRIVQGVCYYNAKEYFGF
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: MPDC_MYCAO
Sequence: MTRTLSADADTRTATPPLMYVNGEWLPARSGATFPTIEPSTGRPITEIPRGDSSDVDAAVKAAADVAVEWQFTDAITRAALLRRLAELVAENAEELARIESLDSGHYLAKARELVTAIPLWLEYWAGAADKVGGRTIAVPGNKLSFTLLEPLGVTAHIIPWNYPLLILARSIAPALALGNTCVVKPAEDTSLSALKFAELVHAAGFPAGVFNVVTGYGSEAGAALAAHPEVRGITFTGSTETGREIARLGGQHIAQVNLELGGKSPLVVFPDAPLEDAVEVAVQGFCSRAGQVCVAGSRLFLHEDIADRFLEMLVSRLETVTVGDPFDGATQMGPLASKKHYDRVREYIEVGKQEATLLYGGGRPTDTPDDGFFVEPTVFVDVATDARIAREEIFGPVTAVMRWSSVDDLIATINDSEFGLFAVLWCRDITSALDTAKRLQVGSVMINDWFGELPMTPHGGHKQSGTGREEGLEAVHGYTQVKHIGINLEPSPAKSADWAGAPL
What is the function of this protein?
Involved in the degradation of methyl tert-butyl ether (MTBE).  Catalyzes the conversion of hydroxyisobutyraldehyde to hydroxyisobutyric acid (HIBA).
What are the official names of this protein?
Hydroxyisobutyraldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_CLOBJ
Sequence: MRKINLLDLETTNKIAAGEVIERPFSVVKELVENSIDAGAKNITIEIEDGGQNLIKIIDDGEGIYPIDIKNAFLPHATSKINSIEDIYKISTMGFRGEALASISSVSKTKLKSRVDSYNFGKEIYIEGGKIEYLKDTGCNVGTTIEVSDLFYNVPARLKFLKSARSDSSSISDIVNRFILAHPDISFNLINKGKQSIKSYGTGNLKDSIRCVYNKTISENLINFESHKDIISVYGFIGKPEISRKSRTNQSIFVNKRYVKSKFITAAVENAFKSFLTVNSYPFFVIFIDIFPEYIDVNVHPTKSEVKFKDERAMFKTIFDAVHEAIKGELKESFTNFFNKEDINMYDSEKSIAETIKLEKEEVQIPIDLNSNNKIDIFGNNINKLPNNAELLKNIGIKEKNTLENNNNFYTSKQNEICYTNKNDECLNSCNKDDYSKIEKPLQKDNKNLDALYLNEHNTNSSPINIKENKPNNFYVDMKIIGQFNNTYILIEKDKELYIIDQHAAHEKVLFEKFKSEIEKGYVISQILLSPVVIELSEDEFNIYEENKDIFKNSGFSVETFGECTINIKEVPLILGKPNVEDLFMDILYNLKNMKSKETSTIKYNAIATLACKSAVKANDNLKEEEIKKLIENMLTLNNPYTCPHGRPTMIKFTLKDLEKKFKRIQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: S45A3_HUMAN
Sequence: MVQRLWVSRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASDHWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPDPRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLTCVAATLLVAEEAALGPTEPAEGLSAPSLSPHCCPCRARLAFRNLGALLPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEPTEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSQSVTAYMVSAAGLGLVAIYFATQVVFDKSDLAKYSA
What is the function of this protein?
Proton-associated sucrose transporter.  May be able to transport also glucose and fructose.
What are the official names of this protein?
Solute carrier family 45 member 3, Prostate cancer-associated protein 6, Prostein.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AQP7_HUMAN
Sequence: MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
What is the function of this protein?
Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (PubMed:9405233, PubMed:11952783, PubMed:30423801, PubMed:30420639).  The channel is also permeable to urea (PubMed:9405233).  Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids.  Mediates glycerol export from adipocytes.  After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia.  Required for normal glycerol reabsorption in the kidney (By similarity).
What are the official names of this protein?
Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, AQPap, Aquaporin-7-like.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, cell cortex. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lipid droplet. Note=Internalized from the cell membrane in response to catecholamine-induced activation of PKA; detected on intracellular membranes and colocalizes with lipid droplets (By similarity). Colocalizes with PLIN1 in adipocytes, probably on lipid droplets (PubMed:27832861).
Protein: FKBP3_MOUSE
Sequence: MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVNAYNHLFESKRFKGTETISKVSEQVKNVKLSDDKPKDSKSEETLDEGPPKYTKSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVELVDID
What is the function of this protein?
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways.  PPIases accelerate the folding of proteins (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYT_ONCMY
Sequence: MEWKIVVPLFAVAFTVANAGLIGGPMDANMNDQGTRDALQFAVVEHNKKTNDMFVRQVAKVVNAQKQVVSGMKYIFTVQMGRTPCRKGGVEKVCSVHKDPQMAVPYKCTFEVWSRPWMSDIQMVKNQCES
What is the function of this protein?
Cysteine proteinase inhibitor.
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUD_XANC5
Sequence: MSETSLLPRAHGAAVLSAAMRSTPDDFQLDELPAFEPSGEGEHLLLTVRKRGQNTAYIAKQLAHWAGIAEMGVSYAGLKDRHAVTTQRFSVHLPKRIAPDIAALDDAQMQVVQSAWHNRKLQRGALHGNRFVLTLRQVQGEREAIEQRLQAIAARGIPNWFGEQRFGRDGANVAAALAMFGHVQAEDGTLLPAPTSRRRLRNDQRSMLLSAARSVLFNRVLGARVAQGSWDSALQGEAWMLDGSRSVFGPEPWSEALAERLARFDIHPSGPLWGVGDLRSADQAAALEQGALSDPQSEALRQGLEAAGLKQERRALRLRPQGLDYRWLEAQTLQLEFALPPGCYATAVLWELGDVTDAGRFNVGMRADA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: S22AO_RAT
Sequence: MAFQDLITQIGCLGRFQILHLIFVLICFILVVPHTVLENFTAAIPSHRCWVPILDNNTMSDNNSRILSQDDLLRISIPMDSNLRPEKCRRYIQPQWDLLHLNGTFSTVTEPDTEPCVDGWVYDQSTFLSTTVTQWDLVCGSQTLNSVAKFIYMTGIFIGHLMGGHLSDKFGRKFIVTCGLLTLAVTETSVAFAPTFLIYCSLRFLTGISSSCIRTNSALLILEWTSPKFQAMVMALIFSAGGIGQVLLGVLAFGIRNWQHLQLAMSVPVFFLLIPTRWLSESARWLIITNKPQEGLKELIKVAHINGIKNSRDVLTLEVVKTTMKDELEAAETKPSPLVLFRTPNLRKRICLLSFVRCVSLISTVGLLINLQYLSNKVFLLQCLYGVVCTPANLLGNFSMNYMGRRTTQIIFMSVMGISILSITFLTQEMQIPRLVLASLGGAISSASLTSTAVLSNELVPTVIRATALGVIGIFGSAGAALSPLLMILMTYSASLPWIIYGVLPILSSLVVLLLPETRNQPLPDSIQDVENKRKSSREVKKDAVAKVTPF
What is the function of this protein?
Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids, as well as bile acids, driven by an outward gradient of dicarboxylates such as glutarate or succinate (PubMed:16079298).  Transports estrone 3-sulfate and estradiol-17-glucuronide (17beta-estradiol 17-O-(beta-D-glucuronate)), but not androstanediol glucuronide (5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)), nor taurocholate (PubMed:31553721).  Prefers sulfate conjugates of steroids rather than glucuronide conjugates (PubMed:16079298).
What are the official names of this protein?
Steroid transmembrane transporter SLC22A24, Organic anion transporter 5, rOat5, Solute carrier family 22 member 24.
Protein: TNNT2_MOUSE
Sequence: MSDAEEVVEEYEEEQEEEDWSEEEEDEQEEAVEEEEAGGAEPEPEGEAETEEANVEEVGPDEEAKDAEEGPVEDTKPKPSRLFMPNLVPPKIPDGERVDFDDIHRKRVEKDLNELQTLIEAHFENRKKEEEELISLKDRIEKRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKALAIDHLNEDQLREKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.
Protein: TRPF_STAAW
Sequence: MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: XGPT_SHIF8
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL14_SYMTH
Sequence: MIQVQTRLQVADNTGAKELMCIKVLGGSWRRYANIGDVIVCSVKEASPGGVVKKGDVVRAVVVRTKKGLRREDGSYIRFDENAAVILKDDKEPRGTRIFGPVARELRDKEFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KAD6_HUMAN
Sequence: MLLPNILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQLYDGYDEEYDCPILDEDRVVDELDNQMREGGVIVDYHGCDFFPERWFHIVFVLRTDTNVLYERLETRGYNEKKLTDNIQCEIFQVLYEEATASYKEEIVHQLPSNKPEELENNVDQILKWIEQWIKDHNS
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates.  IMP is phosphorylated to a much lesser extent.  All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors.  CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP.  May have a role in nuclear energy homeostasis.  Has also ATPase activity.  May be involved in regulation of Cajal body (CB) formation.
What are the official names of this protein?
Adenylate kinase isoenzyme 6, AK6, Adrenal gland protein AD-004, Coilin-interacting nuclear ATPase protein, hCINAP, Dual activity adenylate kinase/ATPase, AK/ATPase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Protein: RBL_GALPR
Sequence: MSPQTETKAGVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEEQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASRGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLASEGGEIIREACKWSP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ORAI_CAEBR
Sequence: MPRSHDPSRVELLRQEGSTMNEKRVSISVEDIRGAVATWKTTSGAPITPYPLPQFFLQPPSSGGGSRNVGGGDGAAGNSKNGSMNSLRMQAYAKKTDDDVDLGHRGELDLSEKYNYDLSKAQLKASSRTSALLAGFAMVCLVELQYDDSTSKPLLIVLGVVTSLLVSVHLLALMMSTCILPYMEATGCTQDSPHLKLKFYIDLSWLFSTCIGLLLFLVEIGVIFYVKFTAVGYPTAGYITTAMLIPVGIVFVLFSYLIHKNRVSHSLGRFKDKVDTMKQFLDVEANLQKSTIAPSTIRDI
What is the function of this protein?
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1.  Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca.  Affects brood size and somatic cell function (By similarity).
What are the official names of this protein?
Protein orai, Store-operated calcium channel.
What is the protein family that this protein belongs to?
Belongs to the Orai family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1303_STRZJ
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SPJ_1303.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: CDCA3_XENLA
Sequence: MGSAESKAQVTPSRPLRNHLLSRVNDPRSPTSGIPRTPIEVGESPRNTPQTVKEEEEEIPDSPEIFDPRSPTNGITRTPLRPPIHAVLNNLAKQLSEVFVAEDSSTEGGPLGFTGPEATNLERQVVESQTAPPAGEHVNDHEVEPSVEKAETQIDLEVCPGVEKVKSPIAEMLETLNDQEESPIAETLETMNDQEESPIAETMNDQEESPIAETLENLNDQAESPIAETLENLNDQAESPIAEMLDTLNDQEPVAVAQSVVSTESTQATGQQQKTRGKSPRSSGVKNVRQRPRKALLSSSSGRSPLRILQEDNSPNTNTQHRQAKKLSFQSEPALPHRALKISHPNWESSLNKENAEYGHSNS
What is the function of this protein?
F-box-like protein which is required for entry into mitosis.  Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.
What are the official names of this protein?
Cell division cycle-associated protein 3, Trigger of mitotic entry protein 1, TOME-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DAPE1_SHELP
Sequence: MSQDVLTLAQDLIARASVTPLDEGCQPLMAKRLAAKGFNIEPMVFEDTTNMWARRGDQGPLFCFAGHTDVVPVGDLNRWHTPPFEPVVIDGYLHGRGAADMKGSLAAMVVATERFVDKHPDHKGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTVKGVQGHVAYPHLADNPIHKAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGSLEVMFNFRYSTEVTAEILIQRVLNILDAHGLDYDISWIFNGLPFLTDAGPLLDATREAIYEITGTETDPQTSGGTSDGRFIAPTGAQVIELGPVNATIHKVNECVKVEDIEQLAKVYERILEKLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase 1, SDAP desuccinylase 1, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TYW2_MOUSE
Sequence: MERECEESVVVAVVTEPRFTQRYRDYLEEQKLLDRLHRVAKLRDGAVALPVLAESLSEQHLQELRDRVAPGSTCVLTRLPDPLPSKKARVRSPAQILCLEVRRWVEDRGVTWSAELEADLPRSWQRHGDLMLLSEDCFQATLWKGLEPELWETVASALGVQRLAKRGRVLPDGTRTPSVTLLLGDHGWVEHMDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSDIADRVNLGLIPSSKEGWPVACQVLRKDVGGILHIHQNVESFSGKTPQPPGSNNVEKEHWPRPQKITTDTQGNGTTENFRGEISSANKPEWWRWAESAETQIASLLHQVHGKPWRTRILHVHPVKSYAPHVDHIVLDLECRPLTSSWPEGVDLLTQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86 (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 2 homolog, tRNA-yW-synthesizing protein 2, tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
Protein: SPC19_YEAST
Sequence: MTDALEQSVLALEGTVSVLKDSVESLKCANEPSTNLASTMLQTKRVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQRELDTLQQTYELNDLRLKKNISMDDDDALNSPDMGQEYEGRDADDVVMMASSTNEELEELKKLKEKKKQLENKLEILKQK
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B.  Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
What are the official names of this protein?
DASH complex subunit SPC19, 19 kDa spindle pole component protein, Outer kinetochore protein SPC19.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.