PharMolix/UniProtQA huggingface dataset:
Protein: KCMF1_XENLA
Sequence: MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLDESSGVRHVRRMFHPGRGLGGPRARRTNMHFTSSSTGGLSSSQSSYSPSNREAMDPIAELLSQLSGVRRSTGGQLNSSGPSASQLQQLQMQLQLERQQAQAARQQLETARNATRRNNASNVTTTITQSTAATNTSSTENNQQSIQNSQFLLTRLNDPKMTEAERQSIESERADRSLFVQELLLSTLMQEESSSSDEDERGEIADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL
What is the function of this protein?
Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase KCMF1, RING-type E3 ubiquitin transferase KCMF1.
What is the protein family that this protein belongs to?
Belongs to the KCMF1 family.
Protein: KCP3_MOUSE
Sequence: MRCCGVCAFDAARGPRRLMRVGLALILVGHVNLLVGAVLHGTVLRHVANPRGAVTPEYTTANVISVGSGLLSVSVGLVALLASRNLLRPRLHWALLTLALVNLLLSAACSMGLLLAVSLTVANGGRRLIADCHPGLMDPSIPLDQGPGHTDCSFDPTRIYDTALALWIPSLFMSAAEAALSGYCCVAALTLRGIGPCRKEGLQEQLQELTELELPECKRQENVQLLHGRQDFQALQKTWV
What are the official names of this protein?
Keratinocyte-associated protein 3, KCP-3.
What is the protein family that this protein belongs to?
Belongs to the TMEM54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS8_PEDPA
Sequence: MSMTDPIADFLTRIRNANMVRHESLEVPASKIKKDMAEILKNEGFIKDVEYIEDDKQGIIRVFLKYGKNNERVISGLKRISKPGLRSYVKSDEVPKVLNGLGIAIISTSEGVITDKEARAKKIGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MURA_MYCPA
Sequence: MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_BACAA
Sequence: MTKWKRANPNGTRDYLFEECTLIEEVEQKLRRTFLERGYEEIRTPTIEFYDVFAFQSRPIDEEKMYKFFDEKGRIIVLRPDMTIPLARVVGTQRCDTPLKVTYSGNVFRANESLAGKYNEIVQSGIEVIGIDNVRAEIECVISVIQSLQKLRVQSFTIEIGQVQLYKCIVKKLSIHEEEEKFLRTYIESKNYASLSNFIRDKKLDRCDETVKLLEKLPRLFGNLEVIEEAEKLASSNEMKMAITRVKEIYEAIEKLGYGSYISIDLGTIQHLDYYTGVIFKGYIYEIGEEIVSGGRYDELIGNFGEMLPAVGLAVQVNQIVKALQEQQEPYERKRIDIMIHYELNRLAEAERLRNLLQKDGKKVALSLFSNLNDTFQFARKNQIVTVVEAKSESLVEYVWKEKWVVQKEGETSCVTFKLR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_COXBR
Sequence: MKPNDKVIIGRLARPYGLRGWIKVVSFTHPIDNLLNHPTWQIQHNNEWQPLKLQAGKLHEPFLVVKLENIDDPETAKHYTNDLIAIERRALGALKEGDYYWTDLIGLAVVNTHGIELGTVDSLIETGSNDVLVVRSKERERLIPYTSYTIQSIDLEKKIIVVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTP_ACACA
Sequence: MSGIAVSDDCVQKFNELKLGHQHRYVTFKMNASNTEVVVEHVGGPNATYEDFKSQLPERDCRYAIFDYEFQVDGGQRNKITFILWAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQATDAAEISEDAVSERAKKDVK
What is the function of this protein?
Forms a one to one complex with monomeric actin.  Can regulate the pool available for polymerization.  Severs actin filaments in a dose-dependent manner.
What are the official names of this protein?
Actophorin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_STRAW
Sequence: MKVKPSVKKICDKCRVIRRHGRVMVICDNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ERA_ECOHS
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: S38A6_MOUSE
Sequence: MQASRHSIQAEPGWYVSAQQPEEAVAADEWSPLLSNEPHRQGSSGASFGLSVFNVMNAIMGSGILGLAYVMANTGILGFSFLLLFVALLASYSVHLLLAMCIHTAVTSYEDLGLFAFGLPGKVVVAGTIIIQNIGAMSSYLLIIKTELPAAISEFLPSDHSGSWYLDGQMLLIIICVGIVFPLSLLPKIGFLGYTSSLSFFFMVFFALVVVIKKWAVPCPVTLDCINEVFQISNATDDCKPKLFHFSKESVYAIPTMAFSFLCHTSVLPIYCELQSPSKKRMQNVTNTAIALSFLVYFVSALFGYLTFYDKVESELLQGYSKYLPHDVIVMAVKLCILFAVLLTAPLIHFPARKALMMILFSNYPFSWIRHSLTTAALNAIIVVLAIYVPDIRNVFGVVGASTSTCLIFVFPGLFYLKLSREDFLSWKKLGALFLLLTGAVVGSFSLVLIIFDWVNK
What is the function of this protein?
Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate.
What are the official names of this protein?
Probable sodium-coupled neutral amino acid transporter 6, Na(+)-coupled neutral amino acid transporter 6, Solute carrier family 38 member 6.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with synaptotagmins and SNAP25.
Protein: MTGA_NITEC
Sequence: MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDRLETMHRQNPAAKLQHRWVDYEQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQRKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILEEFLSKRRILEIYLNVIEWGEGVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPTAKIP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FMT_FUSNN
Sequence: MKIIFMGTPTFAVPSLEKIYKEHEIISVFTKVDKPNARGKKINYSPIKEFALANNLKIYQPENFKDNTLIEEIRNMQADLIVVVAYGKILPKEVIDIPKYGVINLHSSLLPRFRGAAPINAAIINGDTKSGISIMYVEEELDAGDVILQEETEISDEDTFLSLHDRLKDMGADLLLKAIELIKKGEVKAQKQDKKLVTFVKPFRKEDCKIDWTKTSREIFNFIRGMNPIPTAFSNLNGTIIKIYETKINDKVYNNATCGEVVEYLKGKGIVVKTSDGSLIISSAKPENKKQMSGVDLINGKFLKIGEKLC
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: V1R97_RAT
Sequence: MNKDNILHTDTNIKITLFSEVSIGISANSALFFSHLFMLFEKNRSKPIDLYIAFLSLTQLMLLITIGLIAADMFMSRGRWDSTTCQSLIYLHRLLRGFTLCATCLLNVLWTITLSPRSSCLTTFKHKSPHHISGAFLFFCVLYISFGSHLFLSTIATPNLTSDNFMYVTQSCSFLPMSYSRTSMFSTPMAIREALLIGLIGLSSGYMVAFLWRHKNQARHLHSTSLSSKVSPEQRATRTIMILMSFFVVLYILENVVFYSRMTFKDGSMFYCVQIIVSHSYATISPFVFICTEKRIIKLWGSMSSRIVSI
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 97, Pheromone receptor VN5, Vomeronasal receptor 5, Vomeronasal type-1 receptor 41, Vomeronasal type-1 receptor B12, Vomeronasal type-1 receptor B9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALLA_SHIBS
Sequence: MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALVEILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the anaerobic utilization of allantoin as sole nitrogen source.  Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: ECTC_VIBCM
Sequence: MIVRTLEECRQSERRVVAENWESVRMLLKDDHMGFSFHITTIYANTQTHIHYRNHLESVYCMSGEGEIEVVGGKTYPIQPGTLYILDQHDEHYLRAFSSEMVMACVFNPPLTGHEIHDAEGVYPLDKSELISQCHKEK
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: Y205_CLOB8
Sequence: MDRFNCILNDTEYIYYLKRNKKFEKDRKFCKHNLKHFLDVARIAQLINLEESLGFNKEIIYTTAILHDIGKSLQYENGTPHEISSWEISKEILHNYRYNEEEIEIIKQGILGHRDKKSENFAQLMYRADKLSRLCISCKSIDECNWGDEKKNFKIYY
What are the official names of this protein?
Uncharacterized protein Cbei_0205, ORF4.
Protein: LPID_KLEAE
Sequence: MTALLRVISLVVISVVVIIIPPCGAALGRGKA
What are the official names of this protein?
ilv operon leader peptide, ilvGMEDA operon attenuator peptide.
Protein: RSSA_COPC7
Sequence: MTSKLPSILSATEEDIQLLLAAQCHIGTKNCDKQMEPYVWKRRADGIHILNIGKTWEKLVLAARIIAAVENPNDICVISARPYGHRAVLKFAANTGAQAIAGRFTPGSFTNYITRSFKEPRIIIVTDPRVDHQAIREASYVNIPVIALCDTDAPLQFVDVAIPTNNKTRHSIGLIWWLLAREVLRLRGTIPRTPDGWNVMVDMFFYRDPEEVEKQQQEEAAAKAAAAAGAEEAPAGLSEWDVSSAPQAGSINPALVSGEGALDWSADNAGPSDWAADTTTAAGWGAETTGTGGWD
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_PECAS
Sequence: MTNEIRKDAETRMDKCVEAFKNQINRIRTGRASPSILDGIHVEYYGSATPLRQLANVVVEDSRTLAISVFDRSLSPAVEKAIMASDLGLNPSSAGTVIRVPLPPLTEERRKDLIKVVRGEAEQGRISVRNVRRDANDKFKALLKDKAISEDEERRAQDDVQKLTDNFIKKVDVALAEKEAELMEF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB146_ARATH
Sequence: MPTKLPLELEDEILLRVPPLSLTRFRTVCKRWNTLFNDQRFINNHLACVRPQFILRTEKDSKIYSIGINIDDSLEVRELNLETQGPNKKLKVYRNLFYCDGFLLCPALLDEVAVWNPWLRKQTKWIEPKRSRFNLYGLGYDNRRPEKCYKILGFGYGYSSEINGSYNRINPRVSVFEFETNAWKDLKFGLFDWHLRSPRTVLSLNGTLYWIAVRCESGGDGFIQSFDFSREMFEPFCLLPCKNDFGDTQILEVFRGDRLSVLEQCPTTNKIKIWVTKNKISGDRKELVSWRLLMTVSIPNFPRLQDLYSNSQPSYFMDNNDDKRLIVCTCDESGKPCIYIVKGDRFKKIQMGFEVEPWPFHLVYVPSLVPIPLA
What are the official names of this protein?
Putative F-box protein At3g16590.
Protein: ATPA_ACIB5
Sequence: MQQLNPSEISALIKQRIGDLDTSATAKNEGTIVMVSDGIVRIHGLADAMYGEMIEFDGGLFGMALNLEQDSVGAVVLGNYLSLQEGQKARCTGRVLEVPVGPELLGRVVDALGNPIDGKGPIDAKLTDAVEKVAPGVIWRQSVDQPVQTGYKSVDTMIPVGRGQRELIIGDRQTGKTAMAIDAIIAQKNSGIKCVYVAIGQKQSTIANVVRKLEETGAMAYTTVVAAAAADPAAMQYLAPYSGCTMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSAEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPYSIADQAVSVYASNEGYMADVEVKKIVDFDAALIAYFRSEYAPLMKQIDETGDYNKDIEAAIKAGIESFKATQTY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPHL2_HUMAN
Sequence: MSSQAFPAEEDHHNEERQTKKKRKTKHRHKFSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARLPPEERQRIFLTWKKHDFPVQACPFLSLQETQAAASNYATEQSFSCAKRALMRRPGCSLLEKQRIACQQMGYNCFSLENQETPSQQVGSMCSSLEKQGIPSQQVGSQCSYLVAGTEKHPGYALEYGGDTGSEHSTAYRFLSYNSAECLHPPPSSVPYFHGERTETRESQHASPFLLDYAQGAYGVKKDHCLCSFCLSLLQEQQQNDWQYHPQQHQQPQNYSEGMMLQEQLPMDSGPWDLEKQWPSAQSQLQSQLPQNNGKPLCSQLQHVPPQIAANSPLLPLGQDMQVGASSNSGLKCSSFRLRGLHGPATGTQGCSFAKYC
What are the official names of this protein?
Cytoplasmic polyadenylated homeobox-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15A_DAUCA
Sequence: MVRVSVLNDALKSMFNAEKRGKRQVMIRPSSKVVIKFLMVMQKHGYIGEFEYVDDHRSGKIVVELNGRLNKCGVISPRFDVGVKEIEPWTARLLPSRQFGYIVLTTSAGIMDHEEARRKNVGGKVLGFFY
What are the official names of this protein?
40S ribosomal protein S15a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ECOUT
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_FRATF
Sequence: MKSVLGFKKAKVTQEKISMVTCYDYTLAKIINSTDIDCILVGDSGGMVLLGKKNTTYTTLDDMQFMTQAVANGATDKFIVADLPFMSYRQSLETTMQAVMALIQSGAHAIKLEGSSGNLDIIKHIVDSGVPIMGHIGMTPQFINSFGGFKVQGRTEEAAKHLLEEAKLLEQAGCFGIVLECIPANIAKDITQNLDIPTIGIGAGSNTDGQILVLQDMLGMNTDFQPKFVKKYIDGSKLFSDAINTYVKETKANTFPTKEHCYDYC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO1_STAAC
Sequence: MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPLMIEGRKSDEPIALTYDETGTDVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVFIGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIKDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHKINEEVTKYLQVK
What are the official names of this protein?
Probable malate:quinone oxidoreductase 1, MQO 1, Malate dehydrogenase [quinone] 1.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: ALRC_DICDI
Sequence: MFQNNYNNNTNYNNNNFKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQGKCDFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFDFQLSNDDIEKINSLNANIRTCSPITFFGTPFYLFD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
What are the official names of this protein?
Aldose reductase C, ARC, Aldehyde reductase C.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: NSRR_PHOPR
Sequence: MQLTSFTDYGLRALIYLATLPEGELTSISKVTEVYGVSRNHMVKIINKLGQLGYVDTVRGKNGGIRLGMPANRIILGDVVRATEPLQIVNCSEDFCHITPACQLKGILASARSAFLAELDKHTLLSLIDNNPPLLVLLDRPVTE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: RLME_PSEA8
Sequence: MARSKTSQRWLKEHFDDPYVKMAQRDGYRSRASYKLLEIQEKDRILRPGMTVVDLGAAPGGWSQVTSRVIGDRGRLIASDILEMDSIPDVTFIQGDFTEDAVFARILEAIGDHPVDLVISDMAPNMSGVRAADQPRAMYLCELALDLAGRVLRPGGDFLIKIFQGEGFDQYHKQAREMFDKVQMRKPLSSRDRSREQYLLARGFRGE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYP3_YEAST
Sequence: MQNDQQRFSLQNRTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSDHSSSDSALVNGSFRANDHRSVEPSCLGQASPSEHDGNLSVIDLYGDEVESQRAEGEDDDDNNGDNGNEDLEEVHSDDLDLVPDDDNRQRVELEGAASATSANSNGINNTHFDRYGFKKQNNYISEAEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKRYVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLKLSEHDLSKIKPRNNSLNYSWGSNLNQRGGSMGQEDSDMEIFQVIQTFPKTLLNPNEIFEKIIFKRRFNLNRLDQDEIDRCRKFVAAQRLKFKTYGELLGNSTSEADLPINDNTDNKGIHITSDAVNEALSSEVYGFKKSLAGVHWNNSIKEKVKQMRKKKDKGD
What is the function of this protein?
Regulates exocytosis by functioning as a GAP for SEC4.  Stimulates specifically the GTPase activity of YPT6.  Also required for efficient polarization of the actin patches.
What are the official names of this protein?
GTPase-activating protein GYP3, Multicopy suppressor of bud emergence 3, Protein MSB3.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Note=Localizes to the presumptive bud site, the bud tip and the mother- bud neck.
Protein: NUOA_BACHK
Sequence: MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLFLYPWAVAYDDLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEXA_LEPBJ
Sequence: MKDLTDKQQAVLAFITTIIKERGFPPTIREIGDEFGITAKGAYDHLKAIEKKGYLKTAKNQSRAIELIRQSPMESIPVQATSIPVIGRVAAGLPIFADENIESYIPVPDEMAKGNVPMYALRVQGDSMIEVGIDSGDIAIIEKRDIARNGEIVVALIEDEATLKVYYKEQDQIRLEARNPKYKPIKTKKATVIGKLVGLYRIY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PK21B_PSEAE
Sequence: MDSYGDTSGRIGRDWLDRHDEELEQELLDDELNLDELFGPEQEDAPGELSRRRYFRELFRLQRELVKLQNWVVHTGHKVVILFEGRDAAGKGGVIKRITQRLNPRVCRVAALPAPNDREQTQWYFQRYVSHLPAGGEIVLFDRSWYNRAGVERVMGFCNDEQYEEFFRSVPEFEKMLARSGIQLLKYWFSISDAEQHLRFLSRIHDPLKQWKLSPMDLESRRRWEAYTKAKETMLERTHIPEAPWWVVQADDKKRARLNCIHHLLQQMPYREVPQPPVHLPERLRHADYVRHPTPGEIIVPEVY
What is the function of this protein?
Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP.
What are the official names of this protein?
ADP-polyphosphate phosphotransferase, Polyphosphate kinase PPK2 2.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
Protein: ORM2_YEAST
Sequence: MIDRTKNESPAFEESPLTPNVSNLKPFPSQSNKISTPVTDHRRRRSSSVISHVEQETFEDENDQQMLPNMNATWVDQRGAWLIHIVVIVLLRLFYSLFGSTPKWTWTLTNMTYIIGFYIMFHLVKGTPFDFNGGAYDNLTMWEQINDETLYTPTRKFLLIVPIVLFLISNQYYRNDMTLFLSNLAVTVLIGVVPKLGITHRLRISIPGITGRAQIS
What is the function of this protein?
Component of the SPOTS complex that acts as a negative regulator of sphingolipid synthesis.  Acts by inhibiting serine palmitoyltransferases (LCB1 and LCB2) activity.
What are the official names of this protein?
Protein ORM2.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.