PharMolix/UniProtQA huggingface dataset:
Protein: RL30_SHEB9
Sequence: MATKTVKVTQTKSGIGRLPKHRATLTGLGLRRIGHTVELEDTPSVRGMINKVYYMVKVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GABR2_MOUSE
Sequence: MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLSLAPGAWGWARGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSRCLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNSKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
What is the function of this protein?
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:10075644).  Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (By similarity).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (PubMed:10075644).  Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (PubMed:10075644).  Plays a critical role in the fine-tuning of inhibitory synaptic transmission (By similarity).  Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (PubMed:10075644).  Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein. Note=Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane (By similarity).
Protein: Y022_ARCFU
Sequence: MKVKVTLSAVQFRSLVDYESRSFHLDLGEGSTLGDAVRAVEEMLSAEIEPLLERGNVRIMMNNSLVDYQKEKNRVLNDGDALIFITPISGG
What are the official names of this protein?
Uncharacterized protein AF_0022.
Protein: PTFB2_ECO57
Sequence: MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHLAQTA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FrwABC PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-like EIIB component 2, Fructose-like phosphotransferase enzyme IIB component 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_SHIB3
Sequence: MSHPALTQLRALRYFKEIPALDPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HINT_SHIFL
Sequence: MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPMLAHKGL
What is the function of this protein?
Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate), guanosine 5'monophosphomorpholidate (GMP-morpholidate) and tryptamine 5'guanosine monophosphate (TpGd).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase and lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)).  Is essential for the activity of the enzyme D-alanine dehydrogenase (DadA).
What are the official names of this protein?
Purine nucleoside phosphoramidase, Histidine triad nucleotide binding protein HinT, HIT protein.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
Protein: EFTU_CHLTR
Sequence: MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRALSGDGLADFRDYSSIDNTPEEKARGITINASHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKIDMISEEDAELVDLVEMELVELLEEKGYKGCPIIRGSALKALEGDAAYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLRDTKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCLPNSVKPHTQFKCAVYVLQKEEGGRHKPFFTGYRPQFFFRTTDVTGVVTLPEGIEMVMPGDNVEFEVQLISPVALEEGMRFAIREGGRTIGAGTISKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_VIBPA
Sequence: MSEAPKKRWYVVQAFSGFEGRVAQSLREHIKMHGMEELFGEVLVPTEEVVEMRAGQRRKSERKFFPGYVLVQMIMNDESWHLVRSVPRVMGFIGGTSDRPAPITDKEADAILNRLEKASEAPRPRTMYEAGEVVRVNEGPFADFNGTVEEVDYEKSRLKVSVSIFGRATPVELEFGQVEKLD
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: YEZD_BACSU
Sequence: MVSKSTIDPEVIEKIISSLETLDFGTVQITVHDSQITQIEKIEKHRFSLKRKESK
What are the official names of this protein?
Uncharacterized protein YezD.
Protein: HISZ_BRUA1
Sequence: MVGSRTSPIFNALRVELNAREAELVEIPLIQPADPFLDMAGEDLRRRIFLTENENGDSLCLRPEFTIPVCRNHIALNAATPKRYAYLGEVFRQRRDGAAEFLQAGIEDLGAADEAASDARSLADALSCVKAIAPDAPLEIVLGDQSVFAGMLKALGLPQGWRKKLLRSFGDAHSMDLALAELTGTQRRDPLPESLAVLVAEGDEIGLARMLEAEMLEAGISPGAGRTPVEIARRLIEKEDLAATHFPAAALDLLRQFLAIRVSLDMAAVTLRAFAADNALDLGAVLQKFEARADAIAQAGIEMKDIIYDASFGRPLDYYTGLVYEIRDASNRQDGVLAGGGRYDRLLTMLGACEAIPGVGFSIWLDRLQALAGEKQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAC3_HUMAN
Sequence: MVSGRFYLSCLLLGSLGSMCILFTIYWMQYWRGGFAWNGSIYMFNWHPVLMVAGMVVFYGGASLVYRLPQSWVGPKLPWKLLHAALHLMAFVLTVVGLVAVFTFHNHGRTANLYSLHSWLGITTVFLFACQWFLGFAVFLLPWASMWLRSLLKPIHVFFGAAILSLSIASVISGINEKLFFSLKNTTRPYHSLPSEAVFANSTGMLVVAFGLLVLYILLASSWKRPEPGILTDRQPLLHDGE
What is the function of this protein?
Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome.  Reduced iron can then be extruded from the late endosome and lysosome to the cytoplasm by divalent metal-specific transporters.  It is therefore most probably involved in endosomal and lysosomal cellular iron homeostasis.
What are the official names of this protein?
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3, Cytochrome b ascorbate-dependent protein 3, Cytochrome b561 family member A3, Lysosomal cytochrome b, LCytb.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: MTR1B_CAEBR
Sequence: MYVFVDRLSDSVSIPFVSKRAYRKRVNLDDDEDDFVDDPSPTEQKTKAEKKMERMGYKAGEGLGKNKQGIQEPIAISFREGKAGLGHEQWDDSTENKTVEETVIWMTNIDEGIRREICDKLIKDDQWMVVRKEKKVIDDETKFCSEKKLKDMLEAKNVFDSMSEKDIREARTRANPYETIGSAFFLNRSAMKTANMDKIYDWILSRENTGNNSFLLKNPLQEGTTAENVDRHEDLFYFADVCAGPGGFSEYMLWRKAFYNAKGFGFTLAGKDDFKLQKFTASSAYFFETFYGTKKNGDVMDPENIDSLEKLISEGTDGQGVHLMMADGAFSVQGQENIQEILSKRLYLCQLLVSLCIVREGGNFLCNLFDIFTPFSVGLIYLMRVCYDSISLHKPHTSRPANSERFVVCKGLRIECARVVKEYLKRVNRKLDELKNKNSKDDVMELMPLDVIKSDEQFMKEIIEHNEVLAHRQTVYLQKYKSFAKNQGQFDKDQGNLRDECLKYWQVPNKQRPRGGDRGSHLRRGRMGNKFPEFSISMLQSKIPLNIPYEEYRFVALGAASDPQLLIGTGDAVFIYRHGHFEQIDRDYARIPENTILLVDCAEEVKTDGSKIRISSDPHMIRIVDAAVLYGDNVSQLPYEARMKAAQKFALALKLTKKTIQIGWGFRAKDITPHQVCCAQTYSLKELDEFQSNLIELKQRGEVIVLFKEGDRQFKTQSLRLTRIIKQDWQMGWSKSQQVPYVHSPLHQKEGSILEDQWKKREIHSSFWDSVILTNKDKQKMTEMMQHGHNAVPSTIWSWKPCMRTEYGPYKIMNHPEAFDGKPTISAIKSQIAETDLSTQPSNYFY
What are the official names of this protein?
Inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B, Inactive cap1 2'O-ribose methyltransferase 1B, MTr1B.
Protein: PYRG_STRT1
Sequence: MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVYVTDDGVETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKDKIKRAATTTDSDVVITEVGGTVGDIESLPFLEALRQMKADVGSDNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPAGQGIKNKLAQFCDVAPEAVIESLDVEHIYQVPLNMQAQGMDQIVCDHLKLNAPAADMTEWSAMVDKVLNLKKTTKIALVGKYVELHDAYLSVVEALKHSGLANDTAIDIDWVNANDLTAENVASRLADADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEFARHVLHLDGANSAELDPETQYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAAAYGNQEVVQRRHRHRYEFNTKFREQFEAEGFVFSGVSPDNRLMEVVELPDKKFFVAAQYHPEYHSRPNHAEELYSAFVTAAVENAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YDCS_ECOLI
Sequence: MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGYIERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLIMGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPPDSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQYQAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFPKEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPLLGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR
What is the function of this protein?
Catalyzes the formation of short polymers of R-3-hydroxybutyrate (cPHB) (PubMed:18640095).  Involved in natural transformation (PubMed:26826386).  Probably part of the ABC transporter complex YdcSTUV.  During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable).
What are the official names of this protein?
Bifunctional polyhydroxybutyrate synthase / ABC transporter periplasmic binding protein, Poly-3-hydroxybutyrate synthase, PHB synthase, cPHB synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SFR1_DANRE
Sequence: METTPIKPTAADETTPSAEQSSNRSSTAKPMSASLREKLKRSRHSFKSPLSVVKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDSNHTAELPSQQCEALRKAVKERTETLRRLKMVKMYRKKNDLNELQRLTDKWRSCAQSVLYELQRELATGGKQASLSQLIDSFGINDKLLHFDRTEEDFTDT
What is the function of this protein?
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.
What are the official names of this protein?
Swi5-dependent recombination DNA repair protein 1 homolog, Meiosis protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFR1/MEI5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FRLD_BACSU
Sequence: MKLIAVGDNVVDYYQDQETFYPGGNALNVAVLAKRLGHESSYIGIVGNDEAAAHLLNVLKLEQVNADYIRQAHGENGMAIVTLDEQGDRIFVRSNKGGIQSRLRLAFQEKDVSFISGHDLLHTSVYSRLENDLPQLCGLVPVSFDFSTNREDDYLRRVCPYVTYAFFSGSDLSESECGELAKTAHGYGAKMVCMTRGGQGAILSAGDRVYHQPIVEADIIDTLGAGDSFIAGFLTAFCVKQDITYALRQAAETAAKTCGVYGAFGYGYPYRLEDGGSSEKTRIL
What is the function of this protein?
Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates.
What are the official names of this protein?
Fructosamine kinase FrlD.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: APRIO_SHEEP
Sequence: MEHWGEPIPGTGQSWRQPLSTSGRGWLGSAPWRWLGPTSWRWLGSAPWWWLGTATWWWRLGSRW
What are the official names of this protein?
Alternative prion protein, AltPrP.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: ZC3H4_MOUSE
Sequence: MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDGRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEEVQDPPGGQERSRKEKGEKHHSDSEEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKSHRKYRDYSPPYAPSHQQYSSSHNAPLPKKSYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGEHPEDEEDLYEEEIEYGESEEPMGDDDYDDYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGGRGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMSLPTHEPLSPQQLQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHPTGSRLSDPRLSRDPRLSRHAETSGGSGPGDSGPSDPRLARALPTSKAEGSLHSSPAGPSSSKGQPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDVPPVPAALQSLPALDPRLHRSTPPGPPNTRQRPGSTDPSTSGSNLPDFELLSRILKTVNVNTPGQSEKPSDPRVRKTPTDPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGGLGQGSSSGQSSVLSGISLYDPRTPNAGGKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPGVHNLPVPTLFGTVKPAPKTGTGSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ
What is the function of this protein?
RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) (PubMed:33767452).  LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein (PubMed:33767452).  Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome (PubMed:33767452).  The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs (PubMed:33767452).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the suppressor of sable family.
What are the subcellular locations of this protein?
Chromosome. Note=Recruited at sites of high RNA polymerase II occupancy.
Protein: CD5_MOUSE
Sequence: MDSHEVLLAATYLLGTLAAFCLGQSGRGGLDIQVMLSGSNSKCQGQVEIQMENKWKTVCSSSWRLSQDHSKNAQQASAVCKQLRCGDPLALGPFPSLNRPQNQVFCQGSPWSISNCNNTSSQDQCLPLSLICLEPQRTTPPPTTTPPTTVPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSWGGTILYKAKDRPLGLGNLICKSLQCGSFLTHLSGTEAAGTPAPAELRDPRPLPIRWEAPNGSCVSLQQCFQKTTAQEGGQALTVICSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWEALCDSSAARGRGRWEELCREQQCGDLISFHTVDADKTSPGFLCAQEKLSQCYHLQKKKHCNKRVFVTCQDPNPAGLAPGTVASIILTLVLLVVLLAMCGPLVYKKLVKKFRQKKQRQWIGPTGVNQNMSFHRSHTATVRSQVENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSTQPDNSSDSDYDLQVAQRL
What is the function of this protein?
May act as a receptor in regulating T-cell proliferation.
What are the official names of this protein?
T-cell surface glycoprotein CD5, Lymphocyte antigen 1, Ly-1, Lyt-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS13_THEM4
Sequence: MARIVGVEIPNDKKVEIALTYIYGIGKTRAKQICEATNIDPNKRVRELGDEEISKIATFIQQNYKVEGELRTEVMQNIKRLIDIGCYRGLRHKLGLPVRGQKTKSNARTRKGPRPSRIKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y1374_BACAH
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKML
What are the official names of this protein?
UPF0302 protein BALH_1374.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: H2AV2_ORYSJ
Sequence: MAGKGGKGLLAAKTTAAKAAADKDKDRKKAPVSRSSRAGIQFPVGRIHRQLKGRVSANGRVGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKGTIAGGGVIPHIHKSLINKTAKE
What is the function of this protein?
Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A.  May replace conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Probable histone H2A variant 2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MRAY_LEUCK
Sequence: MSDNLWALARAFIITVVFMPFLIKFLKQSKEQAVIRKLGPDHQSKAGTPSMGGLLFVLAAAISAFIGGAAYHGMSGVVAMIIPVFALVAYAIIGGIDDALKLINHADDGFAFKPKLLAQTLSAVVIMLIMWLLGVPFTLYIPMIGTINLGLFYFVFLWFWLVGWSNATNLTDGLDGLLAGNSVVVYAAYTVIAMHMHNHIIVLFNFSIIGGLLGFLIFNRPKAKIFMGDTGSLALGAGLAIESILLGVPFSLIWFGLIFVIETLSVIIQTVGYHFWHKRIFPMAPIHHSFEKFGWSEWQIDLLFWIVSSILAVAGIFYMN
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQGF_CERSK
Sequence: MIHDRIEDFLASLPRTGALAGLDLGTKTVGVAVSDGLRRIATPLLTVRRTKFTEDAAKLKAIADERRLVGIVLGLPRNMDGSEGPRAQSTRAFARNLVQVLPLPVGFWDERLSTVAAERALLEADTSRKRRAEVIDHVAAGYILQGVLDRLDWLGREGGA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_SHEFN
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKIGYGYGKAREVPAAIQKAMEKARRNMVTVELNAGTLHHPVKGRHTGSKVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPAQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GRPE_STRSY
Sequence: MSEEIKNEEIVEEVEATEEVVETPEKSELDLANERAEEFENKYLRAHAEMQNIQRRANEERQTIQRYRSQDLAKKILPSLDNLERALQVEGLTEDVKKGLEMVQESLIQALKEEGVEEVATDVFDPNLHMAIQTVPATDDCPAEHIAQVFQKGYKLHERLLRPAMVVVSE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_ACIF2
Sequence: MGTYALPDAFGHYGPYGGRFVAETLIPALEELERAYQEAQRDPEFRAELHSELRQFVGRPNPLYHAGRLSRELGGAQIYLKREDLNHTGAHKINNAVGQALLARRMGKKRVIAETGAGQHGVATATVATRYGMECLVYMGEEDIQRQSSNVFRMRLLGAQVTAVSSGTRTLKDALNEALRDWVTNVESTFYVIGTVAGPHPYPVMVRDFHRVIGDEARAQCLELTGRLPDCLIACVGGGSNAIGLFYPFIEDRAVRMIGVEAGGLGLGTGQHAAPLTTGRPGVLHGNRTYLMEDEDGQILPTHSISAGLDYPGVGPEHAYLKDTGRAEYVAATDEEALAAFHRLCRTEGIIPALESAHALAHAFRLAPTMRSDQTIIVNLSGRGDKDIHTVAALEGIHL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RS18_LISMH
Sequence: MAGGRRGGRRRKKVCYFTSNGITHIDYKDVELLKKFVSERGKILPRRVTGTSAKYQRKLTVAIKRSRQMALLPFVAEEK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.