PharMolix/UniProtQA huggingface dataset:
Protein: ARGI2_SCHPO
Sequence: MSPHKISDNHRHLMLSRFMMGNGVSIINMPFSGGQPKDGAELAPEMVEKAGLVDDLEHLGYDVKLIQNPEFKSRPSKEGPNQALMKNPLYVSNVTRQVRDAVQRELEQQRVVVNIGGDHSLAIGTVEGVQAVYDDACVLWIDAHADINTPESSPSKNLHGCPLSFSLGYAEPLPEEFAWTKRVIEERRLAFIGLRDLDPMERAFLRERNIAAYTMHHVDKYGIGRVVEMAMEHINPGKRRPVHLSFDVDACDPIVAPATGTRVPGGLTFREAMYICEAVAESGTLVAVDVMEVNPLLGNEEEAKTTVDLARSIVRTSLGQTLL
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: PUR7_METBU
Sequence: MKTEELYSGKAKTIYKTENPNELISEFRDSLTAFDGKKKSEATNKGYYNAQISKKIFEMLEEEGIKTHYLGMVSGNEMLVKKVDIILIEVIPRNIAAGSITRKYPVEEGTVFKEPVLVFDYKSDEFGDPMINDDIAVVMGIATREEIDFIRSMALKINAILKSYLESNGFLLPDFKLEFGRVDGEIVLADEISCDTCRFWDVETGESMDKDLFRFDKGDLSKAYEKVARRLVPEIFEE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: VPR_HV1S2
Sequence: MEQAPEDHGPQREPYHEWTLELLEELKNEAVRHFPRPWLHSLGQYIYSTYGDTWEGVEAIIRILQQLLFIHFRIGCHHSRIGIIPQRRGRNGASRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: B4GT2_CRIGR
Sequence: MSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSIRSPAHALYPAASSSTNCSRPNATASSSGLPEVPSARPGPTAPVIPPCPDVPPGLVGRVVIEFTSPMPLERVQRENPGVLLGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPMLRRQRLRYGIYVINQHGEETFNRAKLLNVGFLEALKEDATYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDVRIGRYRMIKHDRDKHNEPNPQRFSKIQNTKLSMKWDGIGSLRYRVLEVSRQPLFTNITVDIGRPMSWLNQG
What is the function of this protein?
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.  Can produce lactose (By similarity).
What are the official names of this protein?
Beta-1,4-galactosyltransferase 2, Beta-1,4-GalTase 2, Beta4Gal-T2, b4Gal-T2, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Lactose synthase A protein, N-acetyllactosamine synthase, Nal synthase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 7 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.
Protein: PCDGA_PANTR
Sequence: MAAQRNRSKESKDCSGLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLVTAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPTFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEVEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVRATDGGSPPLSTEAHFTLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENARIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQASGGGLTGVSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKKDPLSLLDDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-A10, PCDH-gamma-A10.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ILVD_SYNJB
Sequence: MANSPFPLRSQVVTQGVQRSPNRAMLRAVGFRDEDFGKPIVGIANAHSTLTPCNMGIQTLAERAEAALRTAGCMPQVFGTITISDGISMGTEGMKYSLVSREVIADSIETVVNGQSMDGLLAIGGCDKNMPGAMIAMARLNVPSIFVYGGTIKPGHYNGRDLTIVSAFEAVGEFSAGRISEEELLAVERHACPGAGSCGGMYTANTMSSAFEAMGMSLPYSSTMAAEDEEKAESAAQSAKVLAEAIKANIRPRDIITRKSIENAISVIMAVGGSTNAVLHFLAIAHAAEVPLTLDDFETIRARVPVLCDLKPSGRFVATDLHRAGGIPQVMKMLLNHGLLHGDCLTISGQTIVEVLRDVPDEPSPDQEVIRPWHSPLYPQGHLAILKGNLAPEGAVAKITGVKNPQITGPARVFDSEESCLQAILSGQIRAGDVVVIRYEGPKGGPGMREMLSPTSAIIGAGLGDSVGLITDGRFSGGTYGMVVGHVAPEAYVGGTIALVEEGDLITIDAPARQLHLHVSEEELARRRARWSPPEPRYKRGTLAKYAKLVSSSSLGAVTDLNLWD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TDRKH_BOMMO
Sequence: MSLNTKLALPIALGLSLVTVTAFVAYYVLKRDEEENDNKTVKITKINTIEIHVPKSIVPALIGRNGSNIKDLQKKSGAQIHFKKFTDQDYDVCVVRGRADTTQLAETLIHDFIKQQPTIMSESITVPSWSCGRIIGSGGENVNDISHRSGARVKVESPKSTDKVAEHLVTFRGTKEQIEVAKKLVENCVSLERCRREIEQSKRPPRHSSSPPSPCPSPGDRDADADAQGDVDHTRVKYKRPETTGPSIEVYVSAVSSPSRFWVQFVGPQVAQLDDLVAHMTEYYSKKENREAHTLRHVSVGQVVAAVFRHDGRWYRARVHDIRPNEFDSSQQVADVFYLDYGDSEYVATHELCELRADLLRLRFQAMECFLAGVRPASGEEAVSPSGQTWDKWHPQAVERFEELTQVARWKALVSRTCTYKKTATAEGEKDKEIPGIKLFDVTDEGELDVGAVLVAEGWAVAGPAPSPRPSPPRGHTTPFGDLSKSKVLSMTGGGGRSSSVPKDHKDDGSNVLTVEGDDSKDKDGITASKSLASGLEKSDRHPLSISNFDLSYPDPSRNKQLNGSDDFLHGERQNIDNEITIDTLVPPSPLSNAPILSKTLQDEFKANMNRIDSHHSNLENLGKSAFEK
What is the function of this protein?
Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431).  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431).  Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).
What are the official names of this protein?
Tudor and KH domain-containing protein homolog, Partner of PIWIs protein, BmPAPI.
What is the protein family that this protein belongs to?
Belongs to the Tdrkh family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Note=Localizes to the outer surface of mitochondria.
Protein: DNAG_PYRFU
Sequence: MKRKKTVIHQLISEKQRFEKAKEGGNMAAKDDFGTTKYIIHAEFEANGVVERPDVVGAIFGQTEGLLGDDLDLRELQKTGRIGRIKVEVHTKAGKTYGTILVPSSLDRVETAIIAAALETIDRVGPCEAKIRVIKIEDVRATKRKYIIERAKEILETLMEEEIPETQELVEEVRKAVREMELIEYGPEKLPAGPHVPFSDSIIVVEGRADVLNLLRHGIKNAIAVEGTSIPETIIKLSKERIVTAFTDGDRGGELILKELLQVADIDYVARAPEGKEVEELTKKEIIKALRSKVPADQLLTIVQQRKELFDKLGRERRRGGARKQEYTKKGSLNPQPQVHPNEKIVKPLKVLKPDYKEFEEFIEKVKNDSIALLIDENKNIIKEVPIRDMLSAIESSESIYAVVFNGVITQRLIDIVSEKGAKYLIGARKANVVRRPITLKIITFAE
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: INAR2_MOUSE
Sequence: MRSRCTVSAVGLLSLCLVVSASLETITPSAFDGYPDEPCTINITIRNSRLILSWELENKSGPPANYTLWYTVMSKDENLTKVKNCSDTTKSSCDVTDKWLEGMESYVVAIVIVHRGDLTVCRCSDYIVPANAPLEPPEFEIVGFTDHINVTMEFPPVTSKIIQEKMKTTPFVIKEQIGDSVRKKHEPKVNNVTGNFTFVLRDLLPKTNYCVSLYFDDDPAIKSPLKCIVLQPGQESGLSESAIVGITTSCLVVMVFVSTIVMLKRIGYICLKDNLPNVLNFRHFLTWIIPERSPSEAIDRLEIIPTNKKKRLWNYDYEDGSDSDEEVPTASVTGYTMHGLTGKPLQQTSDTSASPEDPLHEEDSGAEESDEAGAGAGAEPELPTEAGAGPSEDPTGPYERRKSVLEDSFPREDNSSMDEPGDNIIFNVNLNSVFLRVLHDEDASETLSLEEDTILLDEGPQRTESDLRIAGGDRTQPPLPSLPSQDLWTEDGSSEKSDTSDSDADVGDGYIMR
What is the function of this protein?
May be potent inhibitors of type I IFN receptor activity.
What are the official names of this protein?
Interferon alpha/beta receptor 2, IFN-R-2, IFN-alpha/beta receptor 2, Type I interferon receptor 2.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: LONM2_DICDI
Sequence: MGSPTHFGLFLISDAEREVHMEELKSQEASKSKPPSKPKSNFTTFSHGTPDLSKIHKVGMLATVCRTQGYFVLGGGPIIEITGVSNDHDNNNSNLVEITESKNDTSDSTTTTTTTPSTSITPITTPVVPQIPTSKYLKVSIEPHEYSELGDSLTVRALRLQLVKCIYSAINRYQDSSFAQHLKQICMLPIFKMDDSSLLNSIGPLCISSPSEYQKLLECKSLEEKLNMVLSMLVKKCEVFDFNFSIEKQLEEKTMAQQKKYFLTEQMKLIRKELGIDLDEKETIKNKFNSRWKEIAVMDKQILQVFKEEMDKLSSCESNSSEYNTSRNYLDWMTLLPWNVYTNDNFDISKVKEILDRDHYGLKDIKEMIQTFIAVGKLRGSIGGKVILLVGPPGTGKTSVGKSIANALGRQFHRISVGGLSDVSEIKGHRRTYVASMPGKIIQALKTVKTSNPVILIDEIDKISRSSQGDPNSALLEVLDPQQNKNFVDYYLDVPYDLSRVLFICTANDADSIPAPLLDRMEVMTLNGYIQSEQMEIAKRYLLPLVRKETGISEEQLQFTPEAIKKLCELYCREAGVRNLKKFIDKIFRKMAYKLSMGMEQSVIITPDNLEQYVGPIKYPSSRLFQKQKPGIVMGLGGSLIHIESALDRFTNGPTVTTTGSLGLVMRESIDISYSYVKDFLLKVDASNDYFLKNSIHIHAPDGSTQKDISSAGITIVSSLLSLATGKLVKPDLAMVGEVSLTGKVIGVSGIVEKIVLAKRESIKTIIIPKENKKQLEEIPDFIKEGIEIYLVDYYSDVYSIAFTNDSTIKPLIFNDNKENQNENENQSEVKSTIIQ
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PUR5_BRUA2
Sequence: MTMENKPAGQNGLTYAQAGVDIDAGNLMVEKIKPLVRSTRRPGADGEIGGFGGLFDLKAAGFKDPVLVAANDGVGTKLKIAIDADIHDTVGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLSPDQGVAIVSGIAEGCRQAGCALIGGETAEMPGMYRDGDYDLAGFAVGAAERDRLLPRGDIAEGDIILGLASSGVHSNGFSLVRRIVELSGLGWKSQAPFQPGATLGEALLTPTRIYVKPLLAAIRACDGIKALAHITGGGFPDNIPRVLPKGLAAEIDLPAIAVPPVFSWLAKTGNVEPNEMLRTFNCGIGMIAVVNPAKVDEVIAALAAEGEKVVTLGRMTRREKDGVIYKGQLAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_RENSM
Sequence: MRVFGVDPGLTRCGFGVVDVAANRSASLVAVGVIGSSSELPLSQRLLVISESIDQWLDTHSPDVLAVERVFSQTNLSTVMGVAQASGIVIAAAAKRGIAVALHTPSEVKAAVTGNGRADKIAVTAMVTRILKLKVAPTPADAADALALAITHAWRSGPGSTAAAGELTPARKLWLEAEAKARKNVEKSSKQRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CH60_CLOPA
Sequence: AKSILLGEEGRHSMQAGVDKLANTVKVTLG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INS_MYOSC
Sequence: ADPQHLCGSHLVDALYLVCGDRGFFYNPKGIVEQCCHRPCNIRVLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCMC1_XENTR
Sequence: MLEQVQKFLLSRAACEGPDPHTRYAELFHKLDVNKDGKVDIVELQEGLKAMGMAVGKGAEEKIVAAGDTNKDGHLDFGEFIRYLEEHEKKMKIAFTSLDKNKDGKIESAEIMNSLKTLGINISLEHAEKILKSMDADGTLTVDWNEWRDHFLFNPADNIQQIIRYWKHSTVLDIGDSLTIPDEFTEEEKKTGQWWKQLLAGGMAGAVSRTGTAPLDRLKVMMQVHGSKGNANIITGLKQMVKEGGIRSLWRGNGVNVIKIAPETAMKFWAYEQYKKLFTSESGKLGTAERFIAGSLAGATAQTSIYPMEVLKTRLAVGKTGQYSGMFDCAKKIMQREGVRAFYKGYIPNILGIIPYAGIDLAIYETLKTFWLQNYATDSANPGVLVLLGCGTASSTCGQLASYPLALIRTRMQAQASIEGAPQLNMGGLFRKIVAKEGFFGLYRGIAPNFLKVLPAVSISYVVYEKMKIKLGI
What is the function of this protein?
Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane.  Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter.  By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
What are the official names of this protein?
Mitochondrial adenyl nucleotide antiporter SLC25A24, Small calcium-binding mitochondrial carrier protein 1, SCaMC-1, Solute carrier family 25 member 24.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RECR_ECO7I
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HSLV_HAMD5
Sequence: MTTIVSVRRHNHVVIGGDGQVTLGNTVMKGNAKKVRRLHHDKVIAGFAGGTADAFTLFELFEAKLKLCSGQLTKAAVEMAKDWRTDRMLRRLEALLAVADETASLIITGNGDVIQPEDDLIAIGSGGPYAQASARALLENTNLSAREIVEKSLTIAGNICIYTNQYPTIEELKIKTKG
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_VARPS
Sequence: MKILISNDDGFQAPGIVALHDALKDIADVEVVAPEHNNSAKSNALTLAAPLYVHKAHNGFRYVTGTPADCVHIALKGLLGYRPDLVVSGINNGANMGDDTIYSGTVGAAMEAYLFGIPAIAFSQIEKGWAHVDAAAQVARRLVQQIERERMLDGGAFLLNVNVPNRPLQELKPIQVCRLGRRHSAEKVITQESPRGETMYWIAGAGGAKDSGEGTDFHATAAGHIALTPLQIDLTDHANLGQWRETVARLGN
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRC_PSEAE
Sequence: MANQESTTRTLLVALVVCLVSSVFVAGAAVALKPTQAENRLLDKQRSILAIAGLGEPGMSGKEVKALFDSRITAKVVDLQSGTFSDAQDPLGYDPLKAAKDPALSDALPAAEDIASIKRRERYTTVYLVETDGKLDTLILPVRGYGLWSTLYGFLALKGDLNTVAGFGFYQHGETPGLGGEVDNPKWKALWVGKTLYDAQGDLAVQIIKGSVDPQSAKATHQVDGLAGATLTSKGVDNLLHFWLGKDGFDAFLANLRKGEA
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DNAJ_MICAN
Sequence: MPTDYYEILGVSRDAGKEDIKRAYRRLARKYHPDVNKEPGAEEHFKEINRAYEILSEPETRNRYDRFGEAGVSGGAAGFDPDNMGGFADIFETIFSGFGGMGGQATARRRTGPTRGEDLRLDFRLKFREAVFGGEKEIRIRHLETCQTCKGSGARPGTSSRTCTTCSGTGQVRRATRTPFGTFAQVSVCPTCDGAGEVIEEKCDVCGGSGRRQETKKLKITIPAGVDNGMKLRVAREGDAGLKGGPPGDLFVYLTVETDAEFQREGNDIKSDITISYIQAILGCTIKVNTVDGQEDLTIPAGTQPNTVLILENKGVPKLGNPVSRGDHRITVKISIPTRVTGEERELLEKLAKVRGETVGKGGIEGFLGNIFHK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BACCZ
Sequence: MVAVIIKGNEVAEKKRAQLKEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLTEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CH10_ARATH
Sequence: MMKRLIPTFNRILVQRVIQPAKTESGILLPEKSSKLNSGKVIAVGPGSRDKDGKLIPVSVKEGDTVLLPEYGGTQVKLGENEYHLFRDEDVLGTLHED
What is the function of this protein?
Seems to function only as a co-chaperone, along with CPN60, and in certain cases is essential for the discharge of biologically active proteins from CPN60.
What are the official names of this protein?
10 kDa chaperonin, mitochondrial, Chaperonin 10, CPN10, Protein groES.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LINA1_SPHIB
Sequence: MSDLDRLASRAAIQDLYSDQLIGVDKRQEGRLASIWWDDAEWTIEGIGTYKGPEGALDLANNVLWPMYHETIHYGTNLRLEFVSADKVNGIGDVLCLGNLVEGNQSILIAAVYTNEYERRDGVWKLSKLNGCMNYFTPLAGIHFAPPGALLQKS
What is the function of this protein?
Catalyzes the conversion of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) to 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) via gamma-pentachlorocyclohexene (gamma-PCCH) (PubMed:12450824).  Proceeds by two successive 1,2-anti conformationally dependent dehydrochlorinations (By similarity).  Also shows activity with alpha- and delta-HCH, giving alpha- and delta-PCCH respectively, but not with the beta isomer (PubMed:12450824).
What are the official names of this protein?
Hexachlorocyclohexane dehydrochlorinase 1, HCH dehydrochlorinase 1.
What is the protein family that this protein belongs to?
Belongs to the HCH dehydrochlorinase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSBD_PROHO
Sequence: MTTAVGRISDRGWFDVLDDWLKRDRFVFVGWSGLLLFPCAYMAIGGWLTGTTFATSWYTHGIASSYLEGCNFLTVAISTPADSMGHALLLLWGPEAQGAFVRWVQLGGLWTFTALHGAFALIGFMLRQFEIARLVGVRPYNAIAFSAPIALFVSVFLIYPLGQSSWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGGALLCAIHGATVENTLFEDGDDATTFRGFEPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVMGLWMSAIGVVGLALNLRSYDFVSQEIRAAEDPEFETFYTKNILLNEGLRAWMAPQDQPHENFIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.