PharMolix/UniProtQA huggingface dataset:
Protein: M3K7L_DROME
Sequence: MVKQVDFAEVKLSEKFLGAGSGGAVRKATFQNQEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFLGEQYESGTDEDFIKPLDEDTVAVVTYHVDSSGSRIMRVDFWRHQLPSIRMTFPIVKREAERLGKTVVREMAKAAADGDREVRRAEKDTERETSRAAHNGERETRRAGQDVGRETVRAVKKIGKKLRF
What are the official names of this protein?
Putative mitogen-activated protein kinase kinase kinase 7-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: PDE4A_RAT
Sequence: MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYPDSAERSETERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDSQASPGLVLHAGATTSQRRESFLYRSDSDYDMSPKAVSRSSSVASEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNEVEIPSPTPRQRAFQQPPPSVLRQSQPMSQITGLKKLVHTGSLNTNVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMMYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHSAIRQSPSPPLEEEPGGLGHPSLPDKFQFELTLEEEEEEDSLEVPGLPTTEETFLAAEDARAQAVDWSKVKGPSTTVVEVAERLKQETASAYGAPQESMEAVGCSFSPGTPILPDVRTLSSSEEAPGLLGLPSTAAEVEAPRDHLAATRACSACSGTSGDNSAIISAPGRWGSGGDPA
What is the function of this protein?
Efficiently hydrolyzes cAMP.
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 4A, DPDE2.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: HSLU_PETMO
Sequence: MNKIDELTPKKVVEKLDNYIIGQKEAKKQVAIALRNRIRRLSLSEDVRKDVIPKNILMIGSTGVGKTEIARRLAEVANAPFVKVEATRFTEVGYVGKNVESMVRELVDSSVNMVKKEMMEEVKDKAQRLVEERIVEVLVPSKKRAKAQPSFMDVMQLFNQNAEYSQNKDYDENEDENIRRRREELLEKLRNGELEDVEIEVEVEEQSSPMFAGLGPELEDMGIQFGEMFQNLMPKKKKRRRMKISEARKVLEPIESEKLIDQDKLIQEGVSRAENSGIIFIDEIDKITSKGVSSGPDVSREGVQRDLLPIVEGTTVMTKYGSISTDYILFIAAGAFSEAKPSDLIPELQGRFPIRAELSDLTKEDFIRILTQPKNAILKQYQYLLQTDGVKIEFTEDGVERMADIAFELNEKVENIGARRLYTVVEKVLEEVSFEAPASGEWELKIDSNYVDLRLGKVYGDEDLREYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG39_ICHVA
Sequence: MEAIARLDSNALAKIGSGGTPFDSGLHSGVKWFIDNALRLREQFTGPNVRMETYGLSGPGLNMRDFGQKVIVPLLKISIGRYLNRAQAGNLAAFFRLISSTFKPASLPQAQTEFHMLFDITEQRVAQTGNLQTVGGGSTTTTYDIVMSLERKIVTTEIDSLELFYTNDPLVIAESITRELESMQTALDLSVILEHAKFCARQPLLGEMCGLREAARQNDLTDGAIIRACQLENIVCGSLNRSPKNLVSLLHTALKILDISPKDAAVVTTNTVFQNSSLDRRLVESQVGGSDEVYIYSVNGAVGMQPIAKFGKTVPPGEGLRAFNAPVPEVSPGVARSAYGGLKSVDDVMAIHLGNNETIPVIPLDSTKFSVYGNTSVETAMTQECIKRLFFTVGTCPNIYDSLEPGSFFGPSSGTGEEITPAMVAMRSPRSTYIMDLDRGDRVQEITLRQLHRVFLDGNKDAFDTSGFARKIARLTEALEKFNEAEVANLFLEPEWERKMADPGSIFEFDPRQMLIEIPDAEADDVLVVGVDTMNDRAYAAVPRTCMYNSSSLSMKHNEMIGVLSSMLQLVGQSSAITNYCQLVQTALSDTSAEGVEAVNNIRHMDLTGATPPLTRVMVDKITLRGGRYLPLSDPYCQLAIIKYFDDPAAITDVGNRVDVVQTVVNTIRAGFDAIVNVFKTIFDEPDFSIFSVNNMPKSICVTQALTATENLFMNIAYAAILPIFTDTLASMGGGMTVDTETNFNGMVFPVYRNACFIGSGATLPNQVKLWELTGVTKPLLVRAVWKCRTREIMKTFGGQNPFMGFLYHLHLSTLIDKTVILKHFDVKYYSGFSYLCVRTTRFTGHGLSVLPRKSARFITGNMYAGMPISEGTGKHAWTQCMELAVGPAGLDRLGLYIPNIFCTDIHGMGVDFNPRDMYAIAIFDAYNGFTPETKTTASPITNILALSGRYRVEGLGAPDPVTGLYSQCPTLVAGLGAGFDRLRSLVHRLNLPCDHAYAMILAAVDRGNVFETLPVIFSNVEYMRDLELLKRTVDATPADRNLYRETMGLIFADNYVIGKNGEHVFRANTKTVPPTIAALSPKVLGESLYNGAIYGDLEYGFSLKLAKYTGVTTSLRIDLNAV
What are the official names of this protein?
Uncharacterized protein ORF39.
Protein: PSD_CUPMC
Sequence: MNYPHPLIAREGWPFLAGAFIVSVLVHISAGFWGALPLWIVTLFVLQFFRDPPRPIPSAPNAILAPADGRIVVVEKTQDPYAGREALKISVFMNVFNVHSNRSSLDGKVEKLEYFPGKFVNADLDKASMENERNAVVIRRASDGQVVTLVQVAGLVARRILCYINVGDMLSRGQRYGFIRFGSRVDVYLPTDARPRVTIGEKVSASATVLADLDVRA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SPE1_BRAJU
Sequence: MPALALVDTPVDAFSGDCSGVFIPPSPNSSSASLDWSPSLSSSLYRIDGWGAPYFAANSSGNISVRPHGSNTMPHQEIDLTKVVKKATDPKSSGGLALQFPLIVRFPDVLKNRLESLQSAFEFAIQTQGYESRYQGVYPVKCNQDRFIIEDIVEFGSSFRFGLEAGSKPEILLAMSCLCKGSPEAFLVCNGFKDAEYVSLALLGRKLQLNTVIVLEQEEELDLVIALSKKVNVRPVIGLRAKLRTKHSGHFGSTSGEKGKFGLTTVQIIRVVRKLRDVGMLDCLQLLHFHIGSQIPSTALLSDGVSEAAQLYCELVRLGARMEVIDIGGGLGIDYDGSKSGESDLSVAYSLEEYAAAVVASVRFVCDQKSVKHPVICSESGRAIVSHHSVLIFEAVSAGKRHETTPSDLQFLLEGYSEEARGDYENLYDAVMRGDRESCLLYVDQLKQRCVEEFKEGSLSIEQLAGVDGLCEWVTKEIGGSDPVLTYNVNLSVFHSIPDFWGIDQLFPIVPIHRLDQRPVARGILSDLTCDSDGKINKFIGGESSLPLHELDNNGYYLGMFLGGAYEEALGGVHNLFGGPSVVRVLQKDGPHGFAVTRAMMGQSSADVLRAMQHEPELMFQTLKHRAEELSLVHKPGGDKGNDKLVASCLARSFNNMPYLSVGTSTNALTAAINNLVYYSDEAAVGNGGGCGKNGKWSYSVD
What are the official names of this protein?
Arginine decarboxylase, ADC, ARGDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: CLU_DROPS
Sequence: MALEMDSKNSNSAVTGDAAAATTKTNKAKENNNLAGSKKNQSQNLVNGNGTAADGPATKKKGKKNRNKSPPVSTDEAALSNGHVEEKKPEGDGDADADANANVVAVKDEKAEGGDGADAAELDTEDIDLDALHDAGIHVNISCPGSELLTVQLSSMELVQEIHQLLMDREESCHRTCFSLQLDNVTLDNFAELKTIEQLESGSTIKVVEEPYTMREARIHVRHVRDLLKNLDPADAYNGIECTSLTYLNTITQGDLLDKKKTRPDSVDCTPPDYVTPGVFEPPLLPLHPNFKNAKGPQALKVLTTSAWNPPPGPRKLHGDLMYLYVITMEEKRYHISACSRGFFINQSTDDTFNPKPDNPSYLSHSLIDLLSHISPSFRRAFQAIQKRRTLRHAFERVATPYQVYQWAAPNLEHTVDAIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLLRERAIFKVHGDFVTAATRGAMAVIDGNVLAINPGEDSKMQMFIWNNIFFSLGFDVRDHYKELGGDYAAYVAPRYDLHGVRVYNAVDVEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHPKYLELLRQAGKHLKILPHSVYNERDEPVELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLQEVKLSTELVEMGFPIEHRHKLCCLRQELLEAFVEDRYVNFIRIAAVHLQQLNAKKPEETQSEEKKQLPAIEEAEKENKENLNVNETPNEKEKDTPVETKNAEAMVNAIREAQSNVATSNEIQAAEVVKQACAAVGSMKEKEFDFRFNPDVFSPGIRHVDGEEGTSGSVAKQKLLVQDAAEFLVVKQIPAFVKEHLSHSSPPIDGQNLTESLHSHGINVRYLGKVIKALGQMPRMDYLYRIAVMELIVRATKHIYYTYMQSTDPMHLSVAISHFLNCLLTNGPINPVVSNDEMHKKRGGNGGKHNKHKSSKGGKGQQQPAINQNGGSTTSSSSSANAYDWTLVTPRSLWQQIRKESKAYWDWDLDCDSMDSAMSKFGIMRICLLRAFCLKVGIQVLLREYNFDSKHKPTFGDDDIVNVFPVVKHISPRASDAYNFYTTGQAKIQQGLFKEGYELISEALNLLNNVFGAMHQENGSCLRMLARLSYLLGDAQDALAIQQRAVIMSERVNGIDNPSTILEYTHLSLYSFANGHVGMSLKLLYRARYLLVLTCGEDHPEVALIDSNISLILHALGEYELSLRFIEHALKLNLKYFGNKAMHVAVSYHLMARTQSCMGDFRSALNNEKETYSIYKSQLGEKHEKTRDSAECLRLLTQQAVLLQRKMNDIYSNGKLTSDLPPIHITPPSMGSVLEMLNTINGILFVQISQRDIVKVRSEIEKRMKANTDVNEAIKSMVAAANNNGESEVLAPQDNNKEQAATAQQLTNGDKVAVSS
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Protein clueless, Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_YERE8
Sequence: MSLDIDQIALHQLVKRDEQTLDVVLRDSLLPANAVVEEMMAELHRVYSAKSKAYGLFNEQSELADALKRSRKGDEDFLSFSRAATGRLRDELAKYPFAEGGVVLFCQYRYLAVEYLLISVLSSCNSMRVNEQLDLSTTHYLDINRADIVARIDLTEWENNPESTRYLTFLKGRVGRKVSDFFMDFLAASEGLDTKAQNRGLLQAVADYCADAELGKNERQAYRQQVYSYCNEQLQAGEEIALQELAQELPKLGEKDFQQFSVEQGYALEESFPADRGTLRQLTKFAGSGGGLSINFDALLLGERIFWDAATDTLTIKGTPPNLRDQLQRNSGK
What are the official names of this protein?
Nucleoid-associated protein YE1421.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: EUTQ_CLOD6
Sequence: MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSIKLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEIDYVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN
What is the function of this protein?
A bidirectional acetate kinase that may drive flux through the ethanolamine (EA) degradation pathway under anoxic conditions found when this bacteria infects the host intestine.  It may generate ATP that can be used by other enzymes (EutA and EutT) in the eut pathway.  Might serve as an assembly hub for bacterial microcompartment (BMC) shell proteins (By similarity).  Overexpression in E. coli leads to lamellar structures that inhibit cell division (PubMed:23144756).  Expression of the eut operon may allow this bacteria to use EA as a carbon, nitrogen and energy source (Probable).
What are the official names of this protein?
Acetate kinase EutQ, Ethanolamine utilization protein EutQ.
What is the protein family that this protein belongs to?
Belongs to the EutQ cupin-like family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=May be found on the cytoplasmic face of the BMC.
Protein: DADA_PSEMY
Sequence: MRVLVLGSGVIGTASAYYLARQGHEVVVVDRQNGPALETSFANAGQVSPGYASPWAAPGVPLKAIKWLLQKHAPLAIKATGDVDQYLWMAQMLRNCTAARYAVNKERMVRLSEYSRDCLDELRAETGIAYEGRQLGTTQLFRTQAQVDAAAKDIAVLEASGVPFELLDRDAIARVEPALAGVKHKLAGALRLPNDQTGDCQMFTTKLADMAKALGVEFRFGQNIQRLDAVGDRLNGVWIDGKLETADRYVLALGSYSPQLLKPLGVRAPVYPLKGYSLTVPITNAEMAPTSTILDETYKVAITRFDNRIRVGGMAEIAGFDLSLNPRRRETLEMITADLYPQGGDLSQAEFWTGLRPATPDGTPIVGATAYRNLFLNTGHGTLGWTMACGSGRLLADLIGSKRPQISAEGLDISRYSGKNRELEAAPQPLRT
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: HEMH_POLSJ
Sequence: MSFAPEPSFSHGKPPAASCATAILLCNLGTPDAPTAPALRRYLAEFLSDPRVVEIPRPIWWLILHGIILRLRPKKSATKYASIWTPEGSPLKVWTQKQALMLRGYLGARGHTVEVRYAMRYGNPSIASQLNQLKADGATRILILPAYPQYSGTTTASVFDAVYSWAARVRRIPEFRFVNNYHDDPGYISALAERVRTHWRHYGQAGQLVMSFHGVPERTLKLGDPYHCECHKTARLLAEKLGLGKDRYKVTFQSRFGKAKWLEPYTEPTLIRMAQAGIERVDVVCPGFTGDCLETLEEIAMEARHAFLKAGGKEFHYIECLNDSPTWIAALAEFSARQLAGWPTQAPRDTEALRKSGERALAMGAPR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_PSEA8
Sequence: MSDLLSRRLALLGAAANLPLLTECLHGIERECLRVDSDGKLALTPHPRALGSTLTHPQITTDYSEALLEFITPTETDVADTLADLERIHRFASSKLDGEYLWSPSMPCELPDEESIPIARYGSSLIGRLKYVYRKGLALRYGKTMQCIAGIHYNFSLPERLWPLLRQAEGSELSERDYQSAAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRPSQLERLDEHTLYLPYATSLRMSDLGYQNNAQAGLTPCYNDLQSYIDSLRQAVSTPYPPYEKVGTKQDGEWVQLNTNILQIENEYYSSIRPKRVTYTGERPVQALAARGVQYVEVRCLDINPFLPLGIDLDEARFLDAFLLFCAFSDSPLLNGECSDATDNFLAVVKEGRRPGLQLQRRGQPVELQVWANELLERIADTAALLDRARGGEAHAAALAAQRAKVADAELTPSAQVLKVMRERGESFEAFSLRQSREHAEYFRQHPLAAEEQARFEKMASDSLAEQTELERDQDGDFDTFVAAYQASILGLISN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: VIAA_SHIDS
Sequence: MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLTDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSSITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQERMTLSGQLEPILADNNTGAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGESLREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLNQQFRGGTDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: GLMM_STRPN
Sequence: MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GCSH_MARMS
Sequence: MSTIPENLKYADSHEWVLDNGDGTVTVGITDHAQDLLGDVVYVELPEVGTEVTATEQFSLVESVKAASDIYAPVNGEVIEVNDALNDAPELINEAPFEGAWIAKIKLSNAADLDKLLDAAGYSATIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: AROA_SYNJA
Sequence: MLTTASSADILTLSPARGLRGQVSIPGDKSISHRALMLGSLAEGETVIHGLSLGEDPRSTAACFRALGADIPELNSECVRIQGVGLDRLQEPAEVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRSRPMGRVVEPLRQMGANIWGRAGGNLAPLAVQGGSLKGIHYHSPVASAQVKSCLLLAGLLAEGTTQVTEPALSRDHSERMLRAFGAEISVDVAAKTVAVVGGSRLVGQTVQVPGDISSAAFWLVAASIVPESELLLQDVGLNPTRTGVLQVLQEMGADIQVEKRREVAGEPLGDLRVRSARLRGCSIAGDLIPTLIDEIPVLAVAAAFAEGTTVIRDAAELRVKESDRLAAIAQELSRMGAQVTEYPDGLEIKGGIPLQGAEVDSHADHRIAMSLMVAALAAQGSTTLRGADCARISYPDFIPTLQRLINPSSAS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXNL2_HUMAN
Sequence: MVDILGERHLVTCKGATVEAEAALQNKVVALYFAAARCAPSRDFTPLLCDFYTALVAEARRPAPFEVVFVSADGSSQEMLDFMRELHGAWLALPFHDPYRHELRKRYNVTAIPKLVIVKQNGEVITNKGRKQIRERGLACFQDWVEAADIFQNFSV
What is the function of this protein?
May be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors and olfactory neurons.
What are the official names of this protein?
Nucleoredoxin-like protein 2, Rod-derived cone viability factor 2, RdCVF2.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
Protein: YL227_MIMIV
Sequence: MEIDIPKSHKIDTEELSPWISYKKFIDDKTIGYYCVRDQVVIAYKKAYIQDKWDHEKSLINSRLTSYYETVIIELEIPKKSIIVKPKDFKTSGYRTNIAIVRDIFRLKNSQSITESRIFPDIVCFSKYNFGYVYEIGQAAIPSERLETDLDNPLGPGIYFWLDEEKAIQY
What are the official names of this protein?
Uncharacterized protein L227.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L223/L227/L812 family.
Protein: LGT_GEOKA
Sequence: MESTIQPLDRVFLHLGPITIYWYGVIIGTGVLIGLWLATREAVRRGLPKETFVDLVLFAVPIAIVCARAYYVLFEWHYYSKHLSEIPKVWQGGLAIHGGLIGAVATGAVFARARGLSFWKLADIAAPSIILGQAIGRWGNFMNQEAHGGPVSRQFLENLHLPDWIINQMYIDGRYWHPTFLYESLWNLVGFFLLLWLRRVNLRRGELFLSYLIWYSVGRFWIEGMRTDSLMLAGSLRAAQVVSVTLIVLSIALWIVRRAKGWAKARYQDE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCMA_SHESM
Sequence: MTNITSVNTLVSASKLTCIREERILFDELSFDINAGDIIQIEGPNGAGKTSLLRILAGLSRPYAGQTFYLNEDINRCRDEYNEDLLYLGHLAGVKSELTAEENLNFNLRISGYDDFDTAAILAKVNLAGFEEALAGHLSAGQHRRTALARLWHNDCKVWILDEPFTAIDKKGVEELEQLFIQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFV
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GYRA_BUCAI
Sequence: MKDPSREIIQVNIEEELKSSYLDYSMSVIVGRALPDVRDGLKPVHRRILFAMYILNNDWNKAYKKSARIVGDVIGKYHPHGDSAVYDAIVRMAQKFSLRYMLIDGQGNFGSVDGDSAAAMRYTEVRMSKIAHELLNDLEKNTVEFLPNYDGTEYIPEILPAKIPNLLINGSSGIAVGMATNIPPHNLNEVINGCLAYIDNNDITLEELIKHIPGPDFPTAAIINGKSGIEEAYRTGKGKIYIRAQNQIEKNKKNKKESIVFNEIPYQVNKSRLIEKIAELVKEKRIDGITALRDESDKDGMRIVIEIKREAIAEVILNQLYSLTQLQISFGINMVALCQGQPKTLSLKEILKNFLSHRQEIIIRRSLFELNKVRNRIHILEGLNMALININAIIEIIKNSVNSIDAKKIIIQKNWKSEKINYLAKKHEYYFSEKQAQAILDLRLHKITNLEQEKIIMEHNDLIKKTKELKEILENPKKMFEVIKSELLSIQNNFSDKRRTKITENHSDINMEDLINQEDVVVTLSHSGYVKYQPLSDYNAQRRGGKGKSAAKIKEEDFIESLVIANTHDTILCFSSRGILYWMKVYQLPESSRHARGRPIVNLLPLSPKERITAILPVHKYQDNLNIFMTTAHGIVKKSSLSQFKKPRFAGIIAINLHANDELIGVALTDGNNNIMLFTQNGKVVQFLENSVRTMGRTASGVKGIKIKKNDKVVSLIVPKNKGSILIATKNGYGKRTKISDFPIKSRATQGVISIKITKKNGKIIGAIQVIEKDQIMMITDAGTLVRIRVSEVGVLKRNTQGVILIRTSKNEKVVALQKIVDPMIEKIDL
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_CANAL
Sequence: MSSTSKVESAKKLAAYKAVDENFPKDAKVIGIGSGSTVIYAAERIGQLDNKDSFICIPTGFQSKQLIIDNGLRLGTIEQYPDIDIAFDGADEVDPQLNLIKGGGACLFQEKLVAASAKKFVVVADYRKKSDKLGQSWRQGVPIEIVPNSYSKIIQELSKKLGAKNVDLRQGGKAKAGPIITDNNNFLLDADFGEIEIDNVGKLHEQIKLLVGVVETGLFTNMANKAYFGEEDGSVSVWSK
What is the function of this protein?
Involved in the first step of the non-oxidative branch of the pentose phosphate pathway.  It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3BHS7_RAT
Sequence: MADSAQVPALVYLVTGGCGFLGEHIVRMLLEWEPRLRELRVFDLHLSSWLEELKTGPVQVTAIQGDVTQAHEVAAAMAGSHVVIHTAGLVDVFGKASPETIHKVNVQGTQNVIDACVQTGTRLLVYTSSMEVVGPNVKGHPFYRGNEDTPYEAIHRHPYPCSKALAEQLVLEANGRKGLRFGGRLFRAIPASVEHGRVYVGNVAWMHILVARELEQRAALMGGQVYFCYDKSPYKSYEDFNMEFLSPCGLRLIGTHPLLPYWLLVLLTALNALLQWLLRPLVLYTPLLNPYTLAVANTTFTVSTNKAQRHFGYKPLFSWEESRARTIHWVQAMEGSAW
What is the function of this protein?
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.  HSD VII is active against four 7-alpha-hydroxylated sterols.  Does not metabolize several different C(19/21) steroids as substrates.  Involved in bile acid synthesis.  Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase type 7, 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, C(27) 3-beta-HSD, Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase, Confluent 3Y1 cell-associated 2.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NDEL1_RAT
Sequence: MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
What is the function of this protein?
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.  May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome.  Also positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome.  Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate.  Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1.  Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).  Plays a role, together with DISC1, in the regulation of neurite outgrowth.
What are the official names of this protein?
Nuclear distribution protein nudE-like 1, Protein Nudel.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the mitotic spindle and to the microtubules of the manchette in elongated spermatids (By similarity). Localizes to the interphase centrosome. Localizes to the cell body of the motor neurons and colocalizes with assembled neurofilaments within axonal processes. Colocalizes with DISC1 in the perinuclear region, including the centrosome.