PharMolix/UniProtQA huggingface dataset:
Protein: CP1A1_HUMAN
Sequence: MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:11555828, PubMed:14559847, PubMed:12865317, PubMed:15805301, PubMed:15041462, PubMed:18577768, PubMed:19965576, PubMed:20972997, PubMed:10681376).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:11555828, PubMed:14559847, PubMed:12865317, PubMed:15805301, PubMed:15041462, PubMed:18577768, PubMed:19965576, PubMed:20972997, PubMed:10681376).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15-alpha and C16-alpha positions (PubMed:11555828, PubMed:14559847, PubMed:12865317, PubMed:15805301).  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation (PubMed:15041462, PubMed:18577768).  Catalyzes the epoxidation of double bonds of certain PUFA (PubMed:15041462, PubMed:19965576, PubMed:20972997).  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system (PubMed:20972997).  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer (PubMed:15041462).  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid (PubMed:10681376).  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent) (PubMed:21068195).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: HTPX_HELPJ
Sequence: MTNFEKIIAQNRLKTNAVLTTYCAIFAFIGLLVDAIRINANDLGIALFKLMTFQIFPTITIVMFVVAFVIILVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILWVLQIILPFLTLLLQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYTNNDYKEIDKNSTRSAAYLFNAEMFSTHPSIKNRIQSLRKRVI
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: T22D4_MOUSE
Sequence: MSGGKKKSSFQITSVTTDYEGPGSPGASDSPVPPALAGPPPRLPNGDPNPDPGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFGRLLEGIRGASGGTGGRSLDSRLELASLGISTPIPQPGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLAGPGKAKVETPPLSASPPQQRPPGPGTGDSAQTLPSLRVEVESGGSAAATPPLSRRRDGAVRLRMELVAPAETGKVPPTDSRPNSPALYFDASLVHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGLPRLGPSAPNGPSI
What is the function of this protein?
Binds DNA and acts as a transcriptional repressor (PubMed:27827363).  Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (PubMed:27827363).  Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490).  May play a role in neurite elongation and survival (PubMed:20878296).
What are the official names of this protein?
Sperm acrosome developmental regulator, TSC22 domain family protein 4, TSC22-related-inducible leucine zipper protein 2.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRPE_LEPBJ
Sequence: MAETSNSENKTSEEAKASEKNSRSITLEETKLENMNSEESTQTTESTQAQAAEAADSELSLQSELDAAKKEVESLKDSWARERAEFQNFKRRSAQEFVSIRKEAVKSLVSGFLNPIDNLERVGATQSPSEELKPFVEGVAMILKEFYAVLEKSNVIRFDPKGESFDPMSMEALSSEEGDQYSEETVIDVYQAGYYYKENEDKFTLRPARVRIGKPKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCO_PRUMU
Sequence: MENFPIINLEGLNGEGRKATMEKIKDACENWGFFELVSHGIPTEFLDTVERLTKEHYRQCLEQRFKELVASKGLEAVKTEVNDMDWESTFYLRHLPKSNISEVPDLEDQYRNVMKEFALKLEKLAEQLLDLLCENLGLEKGYLKKAFYGTNGPTFGTKVSNYPPCPNPELIKGLRAHTDAGGLILLFQDDKVSGLQLLKDGQWIDVPPMRHSIVINLGDQLEVITNGKYRSVEHRVIAQTDGTRMSIASFYNPGSDAVIYPAPTLVEKEAEEKNQVYPKFVFEDYMKLYAGLKFQPKEPRFEAMKAVETNISLVPIATA
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PLSX_ACHLI
Sequence: MIKLAIDGMGGDNAPKEIVEGSILALKQFDDIELTIFGDVDKMKPYLIEHPRLKVVHTPKYFEMGVKDIGRHTLRDDKDTSMLMAINHVKEGLADGVVSSGPTQALIFASFFMIRPMKEMKRVAIAPMVPTVIGKPTILLDAGGNIDAKAEHLLDFAIFSTIALKEVYGVKSPKVGLINIGTEPGKGRDIDKETFELLSKHPLIDFYGNLEPKEILTSDAQILLSDGFTANIVMKTMEGTASALGKILKREIKASFWGKLAAVLFLKKPLKRFKQSMSADEVGGALIAGLDKVVVKAHGSSEAYAFMNAIRQAKTMVSHDVIGKVKNVLRGQDE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RF3_STRMU
Sequence: MNLQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGNFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPIFTFINKLDRDGREPLDLLEELEEVLGIASYPMNWPIGMGRSFEGLYDLYNQRLELYKGDERFASIEDGDKLFANNPFYEQAKEDIELLTEAGNEFSEEAILKGELTPVFFGSALTNFGVQTFLDSFLAFAPEPHGHKTTDDKVIDPLDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLARTGKSVKLSNVTQFMAESRENVENAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPELFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYTNYQTGEYMLGAVGQLQFEVFKHRMENEYNAEVIMTPMGKKTVRWIKEEDLDERMSSSRNILAKDRFNKPVFLFENDFSLHWFADKYPDIVLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD59B_MOUSE
Sequence: MRAQRGLILLLLLLAVFCSTAVSLKCYNCLDPVSSCKINTTCSPNLDSCLYAVAGRQVYQQCWKLSDCNSNYIMSRLDVAGIQSKCCQWDLCNKNLDGLEEPNNAETSSLRKTALLGTSVLVAILKFCF
What is the function of this protein?
Potent inhibitor of the complement membrane attack complex (MAC) action.  Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).
What are the official names of this protein?
CD59B glycoprotein, MAC-inhibitory protein, MAC-IP, Membrane attack complex inhibition factor, MACIF, Protectin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: TIGD5_HUMAN
Sequence: MYPAGPPAGPVPRRGRRPLPGPPAPAPAPVPAARPPPPAPGPRPRVAVKMAFRKAYSIKDKLQAIERVKGGERQASVCRDFGVPGGTLRGWLKDEPKLRWFLEQLGGEVGTQRKKMRLANEEEIDRAVYAWFLALRQHGVPLSGPLIQAQAEAFARQIYGPECTFKASHGWFWRWQKRHGISSQRFYGEAGPPAPSPAPGPPVKEEPALPSGAGPLPDRAPAPPPPAEGGYGDEQIYSASVTGLYWKLLPEQAAPPGAGDPGAGGCGRRWRGDRVTVLLAANLTGSHKLKPLVIGRLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVKRYLRRSCLQQKAVLLVAHPPCPSPAASMPALDSEDAPVRCRPEPLGPPEELQTPDGAVRVLFLSKGSSRAHIPAPLEQGVVAAFKQLYKRELLRLAVSCASGSPLDFMRSFMLKDMLYLAGLSWDLVQAGSIERCWLLGLRAAFEPRPGEDSAGQPAQAEEAAEHSRVLSDLTHLAALAYKCLAPEEVAEWLHLDDDGGPPEGCREEVGPALPPAAPPAPASLPSAMGGGEDEEEATDYGGTSVPTAGEAVRGLETALRWLENQDPREVGPLRLVQLRSLISMARRLGGIGHTPAGPYDGV
What are the official names of this protein?
Tigger transposable element-derived protein 5.
What is the protein family that this protein belongs to?
Belongs to the tigger transposable element derived protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYN3_HUMAN
Sequence: MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD
What is the function of this protein?
May be involved in the regulation of neurotransmitter release and synaptogenesis.
What are the official names of this protein?
Synapsin-3, Synapsin III.
What is the protein family that this protein belongs to?
Belongs to the synapsin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.
Protein: ODO1_BACC2
Sequence: MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFEIFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAANGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHIQDSEERTWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPDQDISKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFTQEQLKSDYAQVPPADTSDATIHVKVPDVVAKGIQPIDTGVEIDSLRAINEGLLSWPEGFNVYPKVKKILERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTNETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQALFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGTKPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQELIVAHALDVKYNFRQDKQEIEVFSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: CLPAA_SOLLC
Sequence: MMARALVQSTNILPSVAGERAGQFNGSRKDQRTVRMLCNVKCCSSRLNNFAGLRGCNALDTLLVKSGETLHSKVAAATFVRRPRGCRFVPKAMFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDARVEVEKIIGRGSGFIAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLENLGADPTNIRTQVIRMVGESSEAVGASVGGGTSGLKMPTLEEYGTNLTKLAEEGKLDPVVGRQAQIERVTQILGRRTKNNPCLIGEPGVGKTAIAEGLAQRIANGDVPETIEGKKVITLDMGLLVAGTKYRGEFEERLKKLMEEIKQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPSVDETIQILKGLRERYEIHHKLHYTDEAIEAAAKLSHQYISDRFLPDKAIDLIDEAGSRVRLRHAQLPEEARELEKELRQITKEKNEAVRGQDFEKAGELRDREMDLKAQISALIDKNKEKSKAESEAGDAAGPIVTEADIQHIVSSWTGIPVEKVSTDESDRLLKMEETLHTRVIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKSLATYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDFDEKDSSYNRIKSLVTEELKQYFRPEFLNRLSEMIVFRQLTKLEVKEIADIMLKEVFVRLKNKEIELQVTERFRDRVVDEGYNPSYGARPLRRAIMRLLEDSMAEKMLAGEIKEGDSVIVDVDSDGNVTVLNGTSGAPSDSAPEPILV
What is the function of this protein?
May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpA homolog CD4A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_CUPNH
Sequence: MRQKLVIGNWKMHGSLAANAALLEGIKAGAAKATLAVCAPFPYLAQCQALLNGSQVAWGAQDVSAEARGAFTGEVSASMVGEFGCTYVLVGHSERRTYHGETDQTVAAKALRALEFGIVPVVCVGETLAQREAGETEAVVGRQLQAVLDALTVEQLSRVVLAYEPVWAIGTGKTATSEQAQAVHAFLRGQVAARDAGVAERMAILYGGSVKPDNAAELFSMTDIDGGLIGGASLKSADFLAIGNA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_PSYIN
Sequence: MSFESNEYFDGNVKSIAFQSATLPGTLGVMDIGEYTFDTNAYEFMTVVNGALTVKLPGATDWKTFNAGETFEVEANVSFDVKVKVQTAYLCLYK
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TRY1_BOVIN
Sequence: MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
What are the official names of this protein?
Serine protease 1, Anionic trypsin I, Anionic trypsin-I, Beta-trypsin, Cationic trypsin, Pretrypsinogen I, Trypsin I, Trypsin-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: YP93_CAEEL
Sequence: MSANAAWDDSDSENENVVVEEKPVILPRARQPSIAKSLEKVQILENSVAGSEKNASDDDSDASSVMSDDLESLGETTEVLNFSLEQLSMMKKNLAQFPCSYKNIISEFADVEIFLISIDSLIVECAAHSYHNWDVAGQSMVLNKQIDRFLQQFVDIGGRFKLVVFSDLTTQFAKDTTLSFARSTALAHLANGPHARDLLFFTNPTDPEWDKLLNDLTPSFLMISTDNVTQNVCASQEIDLTKQFETIAFDVLTRSMSVVLLHSIKVNFVSVEAYYIQPLLVVAPDWQAFLAAHWDNNGTLLRNHLSKEIKFNQFETPADLWVKVITDAKATGKGSDTFDTLAAAVILSSLICSRRGAHRIYYPTRTDAKRGLNVIRDRRLILNAAVVLLDKADHANSKLDLSDLWDGRMVYSIFDELSANETVLPYRLQDDFAKYHQKAGLTVPLATDTNEKLFDPIPEITDPLVDLPILYSVTSPMIKRFVPEIEKMTSQNAVEEGTVQDYADYLKDTSQWRLKPIEETYAQKEEKIEDAWQLKKANRSKQFLMRWYELFANSLEGRGSNLLVDFSRVPKGYAVVEEEVTDEKKTGKGGWSGQKQQKPGAGGKKGATKESGKSKKDLILEANKKAKDQKVAESEKVKIKYGCQQGKESVIFLNNLYSSLDLPETRALCVYEIAVREGRTIFDQHQGTDKQEVRRNAAIDLVGHLKDCFVKHWDHLESKQKEQIVDLWVSLGFEAPAGSKPSSEAKQKKLNLGINMVYYQLQYGGELIDIQSDPKKDDRVSGFAPDGWQRKMLDSVDRGNSALIIAPTSAGKTFVSYYCIEKVLRSSDNDVVVYVAPSKALINQVCGSVYARFRNKSMKRGISLFGTLTQEYSQNAMQCQVLITVPECLQELMLSRTPAVQKFVSHIKYVVFDEVHSIGASEESHIWEQLLLLIQCPFLALSATIGNANKLHEWLNSSEQAKSAGKRKVELINYGERYSELELSILNINDPHGEDDGAVHKKAGERAVIPLMPYGVYMPEKLRMFSIPEDQQLTARQVLHLYNMMAEVDDATKKEFEPCKFFGQHGTKAVWISRSELRRLENALKERFMEWLSSDEQKINSILKILKEPVNTQLSYRARPFNKEKIANDYIVTLVDDLKEKGELPAICFNDDRHVCEKLAVTLANELERRELEYMETDEFKNKYMIKDESKLVKLAKRKRDDAEKKKKGDKDEDAGPEKDDDEMDVLAMKKAKLARALERFKLRGRNGGDPDIYAKMVERMQKGAKTRESTQVLLKLFERGIGYHHAGLNTVERGAVEVLFRSGNLAVLFSTSTLSLGVNMPCKTVMFGVDTLQLTPLLYRQMSGRAGRRGFDHSGNVIFMSIPTSKVRRLLTASLSNLQGNPPFTVLFLLRLFAYVHQQDILNEEGQKVSTMKQRAFAAKSLLEHSFSIHTRREAQDGILQKQLRMFSAFSFQLLRHLQLLSPFGEGKNFAEMAIHSSSGANGTLLFIYLMQKKCFHQLIKSYDTAEQAQLGILEVLANLFTNLRMTPFHERSDNLENVQVTLRGLPSLLKPYVEEYNSTVTGLYKRFMAASSQDGNLFDPSFAVSGKLDSESVSLTEDFLVAPLFDQYSHDESFLPVIDFNKKDHRGRKIQRNAFAYDFYVHGSRNMLMDVNGLHVSVAWFLLHDFAAILERLAIGVHNMARPQDPLVLVLEELHKNYDEKFRKAFGMRTRD
What are the official names of this protein?
Uncharacterized helicase C28H8.3.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS13_GEOMG
Sequence: MARIAGIDLPRNKRIEIALTYIYGIGRTTAQKILAESGVSVDTRTDSLTEAEVAKIREFIDKNIKVEGDLRRDVSMNIKRLMDLGCYRGLRHRKGLPVRGQRTKTNARTRKGPARTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ACCA_ACTPJ
Sequence: MSQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQVSRMARHPNRPYTLDYIEHIFTEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGRTTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFIDTPGAYPGIGAEERGQAEAIARNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAEKASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLSTEDLLDRRYQRLMSYGYV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SHELP
Sequence: MEPIKNLPRLGRILGYQFQQIALLEQALTHRSAASKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVCGKMLAEIAKEFKLGDYLKLGPGELKSGGFRRESILADAMEAIIGAIYLDADIETCRTLVLNWYKSRLAVIEPVNQKDPKTLLQEHLQGFKQPLPVYTVVNISGEAHAQTFTVECKVEQLKEAVIGVANSRRKAEQIAAAEVLERIKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_ANAD2
Sequence: MPIFRLPREPAFPDPALAEPDGLLAVGGDLEPERLLTAYAEGIFPWFDAESPILWWSPDPRLVLDPAALHVPRSLQRTLRRGAYRVSADEAFERVIRRCAERDRPGQQGTWITGEMVDAYVRLHRLGVAHSFEAWEGDALAGGLYGVSLGAAFFGESMFADAPDASKVAFVRSVEWLRSAGVELVDCQVRTEHLVRFGAREIPRAEFLARLARALEQPTLRGRWQLGGAGPPS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_THEP3
Sequence: MNLTHINEEGRARMVDVSEKAETKREAVAIGSIYMKNETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMITGCDISFNLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: C554A_DICDI
Sequence: MDLLLFIFFLILFYYSVKYYKADNQNSLSLSGPTPVPILGNIHQVGKDAHLTIPIISKKYHGIFRMWLGGTYYVVVSDYKLIREMYIENFENFKNRIATFKTMTGDDSRGIIGCNGDIWDSNKELIMKSYKKVLNKDMNDFILLKSKELFNFFEKNGIKNEEEEDDDDDGNKSIIINNTRFYFQSLTLTVMFKMIFNENKSFQLYSDSTEFKLIFKTILNLLNSLNVYNVIYDFLGIFQPILLKFTKILDKNSFLSKIATEKFNSRIKEIDFTSDDFKANDLLDSLIMTINEDENGLNEKQIENIKSICIDFLMAGTDTTGSTIEWIILKLVNNPEFQELIFQELKKLNKSEITANDKINTPFLNSFIKETNRLYPIAPLSLPRKSINEMIIGDNKYYIPANTNILMDVKGFSLDENNYKDPNEFKPDRFLNSKVSDTLNFGIGPRNCIGQTIAMNQIHIFLSNLILNYRMFSIDCLPLPENLILSVSVRPTEYSLKLIKRV
What are the official names of this protein?
Probable cytochrome P450 554A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL16_ACET2
Sequence: MLMPKRVKHRKVQRGRMKGVATRGNKVVHGDYGLQALEPAWITSNQIEAARIAMTRFIKRGGKVWIKIFPDKPVTKKPAETRMGSGKGSPEYWVAVVKPGRVLFEIAGVSEEVAREALRLAMHKLPIKCKFVAREDEMGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.