PharMolix/UniProtQA huggingface dataset:
Protein: HEM6_AERHH
Sequence: MSKPDVAQVKAFLLQLQDEICRGLELADGAGHFVEDAWRREGGGGGRTRVLRHGAVIEQGGVNFSHVHGDAMPASATAHRPELAGRRFEAMGVSLVIHPHNPYVPTSHANVRFFIAEKEGEEPIWWFGGGFDLTPFYPFEEDVRHWHQLSRDLCQPFGTDIYPEFKSWCDRYFFLKHRDETRGVGGLFFDDLNRWPFADCFAFMQAVGKGYLDAYLPIVERRKALAYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLARWEYDWQPSAGSPEALLYSDYLKPREWL
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGE_SALDC
Sequence: MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAFD_SHIBS
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_METKA
Sequence: MAEETTPRDPFSVTIRTIRTSIRDAISSVYEVDELIEVPIDENPPVEGADLATPVALSLAKELDENPRELAETIVEESDLDDVVFVEKAWVEGPGFINLKLDRSQYAALTLRSIFYYGEEYGSLDLGMGRPVILEHTSANPNGPLHIGHGRNAVIGDILARCMVFTNYGVEVQYYVNDMGKQIAMLAWKYIKEGRPEVPEGEKPDEFFGKLYTEAAREIEEDPELEEVVERFLRSYERYLVEEESRAERIADAFQTVVEECLRGHIQTLERLRVAHDRFVYESEFARDALEIVEKLLDMGVAEEREDGAVVVDLEDYGIDKELVLTRSDGTTLYTTRDIAYHLWKLGRATFVVDVLGADHKLAVEQLRAVLDMLEENPDRIDVVFYEFIHLPEGSMSTRKGRYVTLDEFLEEAKKRALEKMKAAGVAEELSDEEREKIAEEIAIGAVRFAIARVSPNKPIEFDWDEALDFRRGGPFIQYAYARAKSILRKADEEVNRFDAAYLNDDHSFELILKMSKFPRHVAQCVRKRRPDILAEYAYDLAKTFHTFYEEVPVLHVEDDEVREARLKLVEAFTIVAENLMNLLGIPTLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNAC_PARPN
Sequence: MTEGADMARTSRPPVTIASDTLDRLERLAEGAMARNPDLADRLLTELGPRPVPAARADARGCSPASERGHLSRTRPPGASRTVVLVLPEDADIGRRA
What are the official names of this protein?
Uncharacterized protein in napC 3'region.
Protein: MURA1_LISMO
Sequence: MEKIIVRGGKQLNGSVKMEGAKNAVLPVIAATLLASKGTSVLKNVPNLSDVFTINEVLKYLNADVSFVNDEVTVDATGEITSDAPFEYVRKMRASIVVMGPLLARTGSARVALPGGCAIGSRPVDLHLKGFEAMGAVVKIENGYIEATAEKLVGAKVYLDFPSVGATQNIMMAATLAEGTTVIENVAREPEIVDLANFLNQMGARVIGAGTEVIRIEGVKELTATEHSIIPDRIEAGTFMIAAAITGGNVLIEDAVPEHISSLIAKLEEMGVQIIEEENGIRVIGPDKLKAVDVKTMPHPGFPTDMQSQMMVIQMLSEGTSIMTETVFENRFMHVEEMRRMNADMKIEGHSVIISGPAKLQGAEVAATDLRAAAALILAGLVADGYTQVTELKYLDRGYNNFHGKLQALGADVERVDDSKVDVTNLASLF
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAXD1_NOTSC
Sequence: MAPQLLLCLILTFLWSLPEAESNVFLKSKVANRFLQRTKRSNSLFEEIRPGNIERECIEEKCSKEEAREVFEDNEKTETFWNVYVDGDQCSSNPCHYRGTCKDGIGSYTCTCLPNYEGKNCEKVLYQSCRVDNGNCWHFCKRVQSETQCSCAESYRLGVDGHSCVAEGDFSCGRNIKARNKREASLPDFVQSQKATLLKKSDNPSPDIRIVNGMDCKLGECPWQAVLINEKGEVFCGGTILSPIHVLTAAHCINQTKSVSVIVGEIDISRKETRRLLSVDKIYVHTKFVPPNYYYVHQNFDRVAYDYDIAIIRMKTPIQFSENVVPACLPTADFANEVLMKQDSGIVSGFGRIRFKEPTSNTLKVITVPYVDRHTCMLSSDFRITQNMFCAGYDTLPQDACQGDSGGPHITAYRDTHFITGIISWGEGCARKGKYGVYTKVSRFIPWIKKIMSLK
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This protein is functionally similar to blood coagulation factor Xa.
What are the official names of this protein?
Venom prothrombin activator notecarin-D1, vPA, Venom coagulation factor Xa-like protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_PELPD
Sequence: MRSFILACADRVVEGATLGAEEALRLAEARGADLHLLFAEASRIRQHFTGNSASLCSIINAKSGRCAENCAFCAQSAAHKTDAQVYPLVDEEEIVRCARDAERNGARCYGIVTSGTGIRPGAELETICNSLRRIRSETAIAPSCSLGILDEETARLLKDAGMVTYHHNLETSRSFFPSICSSHDYEQDVETIRAVKRAGVRVCCGGIFGLGESFGQRIEMTETLRELDVDSVPLNFLNPVEGTRLEKADFLTPLECLKTIAIYRFMLPGKSLSVCGGRETNLRELQSWIFLAGASGMMTGNYLTTLGRKPEQDHQMLADLGMGVGGCS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NCAP_IPPYV
Sequence: MANSKEVKSFLWTQALRRELGQYCSTVKSSIIKDAQSLLHSLDFSEVSNIQRLMRKDKRNDSDLKRLRDLNQAVFNLVELKSTQQKNVLRVGKLTSDDLLVLAADLDRLKNKVMRTERPQTLGVYMGNLTNQQLDQRKRLLDMIGISNARNAPRPGADGVVRVWDVKDSSLLNNQFGTMPSLTLACMSKQGQYELNDVVQSLTDLGLVYAAKYPNAMDLEKLTQAHPVLSIIDVSKSSINVSGYNFSLSAAVKAGACMLDGGNMLETLKVTPQNLEDILASMLKVKRAHSMFVSDTPGDRNPYENLLYKVCLSGNGWPYIACRTSLTGRAWDNTVVDLGPPIDLSQNKQMSPAKPKGAGHGMPSGLTMSQILALKDLMAAVDPNAKTWIDIEGRAEDPVEIAFYQPQTGAYIHFYREPTDAKQFKQDSKYSHGIDIGDLFNVQPGLTSAVLELLPPNMVLTCQGSEDIRRLLDSQGRKDIKLIDVLMSKSEARKFEDEVWDKFGFLCKIHTGHVVEKKKRGNKEEITPHCALLDCLMYEAASTGRFSPGSIRAVLPRDMVFRAVTEKVAL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: NUCS_SULIN
Sequence: MYSVLLNPSNTEIYSFLTERIYRELVVIFATCKVNYKGRAESVASESPRLIILKPDGTVIIHESVKREPLNWQPPGTKIEIMNDYPLKIVAQRKRPKEVIEIDLKEVFYITSAEVKDGDFVIKGREIDIVNTIIQNPSMIEEGFVPLTREYNTPYGKIDLVGLDKKGNFVIIEVKRSKAQLSAVSQLYRYYLHIRETKEDKVRGILVAPDLTTHARELLQKLGLEFIRYDIQKYSSY
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BBSD_THAAR
Sequence: MGIQNRVALITGSASGMGKQTALRFAEQGAAVVINDIDAEKVRATVDEFSARGHRVLGAVADIGNKAAVDGMVKQTIDAFGRIDILVNNAGMERAGALRKLSEADWDVTINVNLKGTFLCTQAVHGHMVENKHGRIVNIASRAWLGGAGQTPYSSAKAGVVGMTRALAIELGRAGITVNCVAPGLIHTPMWDELPEKDQQFLLSRQPTGKLGEPDDIANTLLFLADDDSGFVTGQVLYVCGGRSLFAG
What is the function of this protein?
Involved in an anaerobic toluene degradation pathway (PubMed:10629170).  Active subunit that catalyzes the oxidation of 2-(alpha-hydroxybenzyl)succinyl-CoA to 2-benzoylsuccinyl-CoA (PubMed:34601806).  In vitro, can catalyze the NADH-dependent reduction of the artificial substrates 2,2-dichloroacetophene and 2,4'-dichloroacetophenone (PubMed:34601806).
What are the official names of this protein?
(2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD, (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ECSIT_MOUSE
Sequence: MSWVQVNLLVRSLSRGWGGLCRPALSGTPFAQVSLQALRGLHCSAATHKDEPWLVPRPPEPQRKPIKVPAMHEDLFKPSGNRERDKASFLNAVRSFGAHNVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNVIQRIFVHYPRQQECGVAVLEQMERHGVMPSAETEFLLIQIFGRKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHMEPDLSAKVTVYQMSLPSDSTGMEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILRADLPPPEEEKVEEIPEEWELYYPQKLDLEYSRSGWDDYEFDVDEVTEGPVFAMCMAGAHDQATLIKWIQGLQETNPTLAQIPVVFRLARSTGELLTTSRLEGQSPPHSPPKGPEEDDETIQAEQQQGQS
What is the function of this protein?
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
What are the official names of this protein?
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Protein SITPEC.
What is the protein family that this protein belongs to?
Belongs to the ECSIT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: MDTI_SHIBS
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PKHA3_HUMAN
Sequence: MEGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS
What is the function of this protein?
Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane (PubMed:15107860).  Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration (PubMed:30659099).  Binds preferentially to PtdIns(4)P (PubMed:11001876, PubMed:15107860).  Negatively regulates APOB secretion from hepatocytes (PubMed:30659099).
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 3, PH domain-containing family A member 3, Phosphatidylinositol-four-phosphate adapter protein 1, FAPP-1, Phosphoinositol 4-phosphate adapter protein 1.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Localizes to ER-trans Golgi network (TGN) contacts sites.
Protein: CH10_CERS1
Sequence: MAFKPLHDRVLVRRVQSDEKTKGGLIIPDTAKEKPAEGEVVSCGEGARKDSGELIAMSVKAGDRVLFGKWSGTEVTIDGAELLIMKESDILGILS
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCP5_MOUSE
Sequence: MGIFPGIILIFLRVKFATAAVIVSGHQKSSTLSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
What is the function of this protein?
Participates in the mitochondrial proton leak measured in brain mitochondria.
What are the official names of this protein?
Brain mitochondrial carrier protein 1, BMCP-1, Mitochondrial uncoupling protein 5, UCP 5, Solute carrier family 25 member 14.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AROQ_BACAC
Sequence: MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ATP6_ECO27
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS8_CLOPE
Sequence: MVMTDPIADLLTRVRNANSVRHEVVEVPSSSVKKAIVNILLQEGYLKGVEEYNDGVVPMMRLTLKYGANNERVITGLKRISKPGLRVYCKKDEVPRVLNGLGIALISTSKGLVVDREARKLGLGGEVICYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: OPSD_CAMMA
Sequence: LHMIHLHWYQYPPMNPMMYPLLLVFMLITGILCLAGNFVTIWVFMNTKSLRTPANLLVVNLAMSDFLMMFTMFPPMMVTCYYHTWTLGATFCQVYAFLGNLCGCASIWTMVFITFDRYNVIVKGVAGEPLSTKKASLWILTIWILSITWCIAPFFGWNRYVPEGNTGCGTDYLSEDILSRSYLYIYSTWVYFLPLAITIYCHVFIIKAVAAHEKGMRDQAKKMGIKSLRNEEAQKTSAECRLAKIAMTTVALWFIAWTPYLLINWVGMFARSYLSPVYTIWGYVFAKANAVYNPIVYAIS
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Can use both retinal and 3-dehydroretinal as visual pigment.  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Signaling via GNAQ probably mediates the activation of phospholipase C.
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Detected on the rhabdomere membrane in the photoreceptor outer segment.
Protein: RL7_PARMW
Sequence: MSAKTDEILESLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAAAGGGGGEVAEEKTEFDVILESFDAAAKIKVLKAVRNATGLGLGDAKALVEAAPKPIKEGISKDEAEALKKEIEEVGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL21_SALHS
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DUT_METCA
Sequence: MPKIQIRILDSRLGNEIPLPHYATPGAAGLDLRACLDASLVLQPGETRLIPTGFAIHIGDPDLAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGQVLVSCWNRGPEPFEIAVGERIAQMVFVPVVQVSFEQVEAFAESRRAEGGFGHTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PCXA_SYNS9
Sequence: MSRRNWVNFFSRGQGFDLTNDLERGYESALLIQNLELEFYGDRLVRSDVELGVPKSVQASILRRFRAALLICRTTLESVERNRGQFDLQELRQLQLIEAVVSRYGYQLPSGGSPAISRAPEALPRSLLGFFDTVRRQLDPASEETVVAGFRRRRNSTLISLRILLLLILVPLLIQQVAGAYIISPAVDRLSPELPFLSYPKPKLEEQAVEKLRVYKQELEFDALLNSDQPLEADQLRQKLAEKAIELKDEADGLSVQAVKNVFSDLSALIAFTVVCFASRDDLRVMRGFFDEAVYGLSDSAKAFAIILFTDIFVGFHSPEGWTVLLNGIAKHLGLPSQENFVMLFIATFPVILATIFKYWIFRYLNRVSPSSVATLKGMNGSG
What is the function of this protein?
Involved in light-induced Na(+)-dependent proton extrusion.  Also seems to be involved in CO(2) transport.
What are the official names of this protein?
Proton extrusion protein PcxA.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK3_SPIOL
Sequence: MAAILPTFSIKSSSCTYSSSKRSLSSPKAVSLSSSVNGTPKVQSLRLSTSFVCSPNQIIKLKSVSPSRSTQLRRAVGGLEIKMMSVDAGIGVMGTKLGMMSFFEEDGTVVPVTVIGFKEGNIVTQVKTESTDGYNAVQVGYERLRDRKLTMPERGHLNKAGVIPMRHLQEFRLVSVDDFTPSQKLLFEELFKEGDMVDISGTTIGKGFQGGIKRHNFKRGLMTHGSKSHRALGSIGAGTTPGHVYKGKKMPGRMGGTKTKIRKLKIMKIDTDLRVVMIKGAVPGKPGNLLRLAPAKIVGKNIPKN
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic, Chloroplastic large ribosomal subunit protein uL3c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXD_XYLFM
Sequence: MPIFTAQELAERFNLQLFGDGNIRIHGVATLAQASPEQLSFLANPRYLTQLLNSRAGVIVLHADDVKAASGTVLIAKDPYVTFAKIATLFDIKPAREAGIHPLATVDPSAHVSPTAHVGAFVSIGARSSIGASCIIGTGSIIGDDCTIDDGSELIARVTLISRVRLGKRVRIHPGAVLGGEGFGLAMESGHWIKIPQLGGVVIGDDCEIGANSCIDRGALDDTVLEEDVHIDNLVQIAHNCRIGAHTAIAGCTGIAGSAKIGRYCLLGGHVGVVGHLQICDNVVITGKSVVRNSIHTPGEYSSGTPLTDNRTWRKNAVRFKQLDMLVRRMMAVSKEKA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: ARLY_STAA2
Sequence: MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKCL2_RAT
Sequence: MHQIPTVGLGTWKASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGDKDIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAYRPLGGSRDGVHLMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPSTENHKDYPFHIEY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.
What are the official names of this protein?
1,5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAL_PYRFU
Sequence: MEGVIVPLVTPFKEDYSIDFEALEWHIEFLEDKGVHGIFTNSTTGEFTSLSFEEKKLLAEKGRELTSKAYYLVGTGSTNTFEVIELTKHAKDIGADATVIVSPYYCKLKDEAIFRHFSIVAERADIPIILYAIPSCANPINVEIVRKLALEHSNIIGIKASVDSLTYLGELLEVKEERKDFKVFTGLDQYFFTLLTLGGDGGIMACANFAPEIHLEIWNAFKEKNFRRAIELARELVRITKIYKIASSFASAVKLAMVAKGFPIRPVLRPPYVIDGEEVFNEIREIVEWRQMLRKESL
What are the official names of this protein?
Uncharacterized DapA-like lyase PF0657.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLC1A_HUMAN
Sequence: MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD
What are the official names of this protein?
C-type lectin domain family 1 member A, C-type lectin-like receptor 1, CLEC-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.