PharMolix/UniProtQA huggingface dataset:
Protein: IZH3_ASHGO
Sequence: MSHPNTHMPRTHAVHGRAAPQRRGCRTSVEKTDQSGHSRSSLAESAMEQAQLRSRGEAGGGRSVLCASGEPGSAHKWAGAVTCSGAEEQPLHWAESRARGLARHLHYWELPYAWRENRYIIYGHRFYHSHRKSLLSVLNAYGWHNETINIWSHLVGAAVLAYLLCWGWPRSDVYRAAQVPRLAKWAIGAFLACGVKCMASSVAWHTFNGTCHLKLRSRFVCVDYTGITLLVTASVVTTVAVTLYGLSRPLMYAYMVASIGLGTAAGVMNWSPHFDRPEARPLRIAVYVGLAALGLVSFVHVWMQVRWASAHLMAPLVYKSLVWYGIGVVFYATLVPERWRSDVTLDCCSGPVHEAACRQFRDLPPVARKDRQFWSLWWVDYFCHSHFLWHVFVVLGVVGHYRAVLQMSRIVWLDAGRAF
What is the function of this protein?
ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels.
What are the official names of this protein?
ADIPOR-like receptor IZH3.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SASA_PARMW
Sequence: MGEDDPKGRQRLKLLLVAARHHLSGPDLRSVVHYLERDDVGFQVTLQLADPSQQPELLELHRLVITPALIKLSPAPKQVFAGSNILQQLKGWVPRWQQDGVVSGLGLSLRPTELDGSRTQKELQLEDQLLVLRQENETLIDRIHAQERLLRMVAHELRTPLTAAALALQSQRLGQIDMTRFQDVITRRLEEMEALSKDLLEVGTTRWETLFNPQRLDLASVSAEVILELEKLWLGRNVEIRTDIPSDLPKVFADQRRMRQVLLNLLENALKYTGNGGHITLTMLHRTSQRVEVSVCDSGPGIPTEEQQRIFLDRVRLPQTSDRTTGFGVGLSVCRRIVEVHGGRIWVVSEPGEGACFTFTVPIWQGQGQEWGQAVLTEGELEP
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: GATB_NEIMB
Sequence: MTWETVIGLEIHVQLNTKSKIFSGASTAFGAEPNAHASVVECALPGVLPVMNREVVEKAIKLGLALDAKINQKNVFDRKNYFYPDLPKGYQISQLDLPIVEHGKLEIVVGDDVKTINVTRAHMEEDAGKSVHEGLNGATGIDLNRAGTPLLEVVSEPEMRSAAEAVAYAKALHSLVTWLDICDGNMAEGSFRVDANVSVRPKGQEEFGTRREIKNLNSFRFLEQAINYEAEAQIEILEDGGKVQQATMLFDPEKGETRVMRLKEDAHDYRYFPDPDLLPVIISDAQMQKAKAEMPELPKEMAARFVADYGVSEYDARLLTASRAQAAYFEEAAKESGQGKLTANWMNGELAAALNKEGMELADSPITAPRLAALVGKIADGTLSSKLAKKAFEAMWAEPEATIAEIIEKHGLQQMTDTGEIEAMVDEVLANNAKAVEQFKSGNEKALNAIVGQVMKASKGKANPAQVQELIKAKLA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SRPX2_BOVIN
Sequence: MAIQLTRRGALSLLLFLTPAVMPTWYAGSGYYPDESYNEVYAEEVPQTPILDYKVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPVVKDSADGTITRLTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPLHGYLTCTSAGDNYGATCEYHCDGGYERQGTSSRVCQSSRQWSGSPPVCVPMKINVNVNSAAGLLDQFYEKRRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREHQLSANIIEELRQFQHLTRSYFNMVLIDKQGIDRERYMEPVTPEEIFTFIDDYLLSNEELIQRREQRDICD
What is the function of this protein?
Acts as a ligand for the urokinase plasminogen activator surface receptor.  Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords).  Involved in cellular migration and adhesion.  Increases the phosphorylation levels of FAK.  Interacts with and increases the mitogenic activity of HGF.  Promotes synapse formation (By similarity).
What are the official names of this protein?
Sushi repeat-containing protein SRPX2.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cell surface. Synapse.
Protein: MORO_PTEVL
Sequence: MKCIALFLVLSMVVLMAEPGEAFIHHIIGGLFHVGKSIHDLIRGKNRDMAEQQELERAFDRERAFA
What is the function of this protein?
The non-amidated peptide only inhibits growth of human pathogens like S. aureus or E. coli, and the fish pathogen A. salmonicida.  Induces hemolysis of erythrocytes from human and fishes (sea bass and lesser-spotted dogfish).
What are the official names of this protein?
Pteroicidin-alpha, Alpha-Pte-CONH2, Alpha-Pte-COOH, Piscidin-like peptide.
What is the protein family that this protein belongs to?
Belongs to the pleurocidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LUTA_EXISA
Sequence: MPNVALFVTCLSDTLFPSVGQATVELLEHLGCEVTFPFEQTCCGQPAYNSGYHEETKKIAKHMIETFEQADAEYIVGPSGSCVMMMRDYPHLFQDDPVWRPRAEAHAAKTFELTQFIVDVLEVTDVGAKFPAKATYHASCHMTRLLGIEAAPGKLLGNVDGLTMVPLANVHNCCGFGGTFSVKMPDVSVQMVDEKVDSILQSGAEVLIGADASCLMNIGGRLHKQGHPIKVMHIAEVLNEGVKQA
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: GPSM3_RAT
Sequence: MEAERPQEDGEQSLPQDDQGWPPVNSTARPWRSAPPSPPPPGTRHTALGPRSGSLLSLQTELLLDLVAEAQSRRLEEQRAAFHTPKVPPSLAPTPPRLLEDKEQLYSTILSHQCQRIEAQRSDPPLPPGGQELLELLLRVQGGGRMEDQRSRPPTHTC
What is the function of this protein?
Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.
What are the official names of this protein?
G-protein-signaling modulator 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LINE_SPHIU
Sequence: MMQLPERVEGLHHITVATGSAQGDVDLLVKTLGQRLVKKTMFYDGARPVYHLYFGNELGEPGTLYTTFPVRQAGYTGKRGAGQISAVSYNAPVGTLSWWQEHLIKRAVTVSEVRERFGQKYLSFEHPDCGVGFEIIEQDTDGQFEPWDSPYVPKEVALRGFHSWTATLNRNEEMDSFMRNAWNLKPQGRDGNYQRYAFGNGGAAKVLDVYIDEDERPGTWALGEGQVHHAAFEVADLDVQAALKFDVEGLGYTDFSDRKHRGYFESIYVRTPGGVLFEASVTLGFTHDESPEKLGSEVKVAPQLEGVKDELLRTMNDPIVI
What is the function of this protein?
Cleaves aromatic rings with two hydroxyl groups at para positions with consumption of O(2).  Catalyzes the cleavage of chlorohydroquinone (CHQ), as part of the gamma-hexachlorocyclohexane (gamma-HCH or lindane) degradation pathway, producing 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate as an intermediate product that can react with water yielding maleylacetate.  This degradation pathway allows S. japonicum UT26 to grow on gamma-HCH as the sole source of carbon and energy.  Can also use hydroquinone (HQ) as substrate, leading to gamma-hydroxymuconic semialdehyde.  Is not able to convert catechol, contrary to meta-cleavage dioxygenases.
What are the official names of this protein?
Chlorohydroquinone/hydroquinone 1,2-dioxygenase, (Chloro)hydroquinone 1,2-dioxygenase, (C)HQ 1,2-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: RGPS2_MOUSE
Sequence: MDLMNGQASSVTIAATVSEKSSSSESLSEKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPILPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGASTPRSAASREDLAGPDIGASPQGGRKSSAAAAAAAAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVPRNGYRSHTKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
What is the function of this protein?
Guanine nucleotide exchange factor for the small GTPase RALA.  May be involved in cytoskeletal organization.  May also be involved in the stimulation of transcription in a Ras-independent fashion.
What are the official names of this protein?
Ras-specific guanine nucleotide-releasing factor RalGPS2, Ral GEF with PH domain and SH3-binding motif 2, RalA exchange factor RalGPS2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.
Protein: TRUA_STAAN
Sequence: MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEISDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LNT_ECOLI
Sequence: MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGLQALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLSLYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPLKGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQPEKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEINQQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITAVIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLRQRRK
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation (PubMed:2032623, PubMed:21676878, PubMed:28885614, PubMed:28675161).  Utilizes a two-step reaction via a ping-pong mechanism (PubMed:21676878, PubMed:28675161).  Lnt undergoes covalent modification in the presence of phospholipids, resulting in a thioester acyl-enzyme intermediate.  It then transfers the acyl chain to the amine group of the N-terminal diacylglyceryl-modified cysteine of apolipoprotein, leading to the formation of mature triacylated lipoprotein (PubMed:21676878, PubMed:28675161).  In vitro, can utilize the phospholipids phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidic acid (PA) or cardiolipin (CL) (PubMed:2032623, PubMed:21676878).  PE is the most efficient acyl donor (PubMed:21676878).
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase, Copper homeostasis protein CutE.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: D13_FOWPV
Sequence: MNNSIISSVINSIDSSSKRTNIFSFDVQQPTAYMPQYISVNGYHNKKDNDANQVCSVSFDIRDQHIAAINYFFISIQLPEVSGEGKFAYVPYVGYKCIQHVAITCGDITIWETDGEELFDKCVDDKIASLSGYSPELNDISTGYTPNDTIKDPTTLYVYIKSPFDADKTISSLKLVNNKITVTITFRSINDVIVYDSKFQVERFVKDFVYSTELHLIAYAVSDIKPKSAYIELDRRVVSCSSTPTPIPVISDVYACTAMSVYVKPYYGMMENKFISYPGYKQTESDYVRCMVNRLLDDLVVVADTVPKGFPSTATFVKVPVDGQINLQDVDIIVKIDNVPDDKDIYYHTNLLIFGTRKNSFVYNISKKFSSIIGMYSPNTDSINFSKVNHTISITDASIPVSFWVSQKNVYQGDNRSNYSKSKDLVVNDPFRKGIDMVNKTDVISRLEVRFGNDPIYSEISPITKVFNMLLTGSSINMRKIIFNMNPANIFRPTTLNANTKRGKDKLTVRISYIDTDPNNPIHYVAKQLVVICTDLYRIDYDGNINITKITE
What is the function of this protein?
Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV).  This association occurs concomitantly with viral membrane formation.  Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis.  In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm.  This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus (By similarity).
What are the official names of this protein?
Scaffold protein, 62 kDa protein, D13 ortholog, N3L protein, Rifampicin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein D13 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Associates transitorily with crescent and IV membranes.
Protein: Y4XE_SINFN
Sequence: MTDLEELKQRVQKLQSRAATAKTQLHDLAECLPNYWTEIVAVAEKTFDAFAQLDAAKRELAASENSR
What are the official names of this protein?
UPF0437 protein y4xE.
What is the protein family that this protein belongs to?
Belongs to the UPF0437 family.
Protein: PYG_PORPU
Sequence: MSIPLLNYSLSTQNQRVDGYEVSPGEEQPRAYNTDNLPSAVEMDEVIWAAYRQIFSEHQILSSTSAPYLESQLRFNQIKVKDFIKGLILSESFRKLNYDVNNNYRFVEICVQRILGRDVYNEREKLAWSIVIASKGLESFINMLIESDEYEENFGDSIVPYQRRRIIAQRSKGEMPFNLKTPRYGADFKEKFGMPQFIWQGPVRQFRPQEQRPKAGDPALFLGMVNDLATV
What is the function of this protein?
Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome rod-core linker polypeptide cpcG.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: WECF_ECO8A
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDLSNEHVAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEGA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y2338_MYCBO
Sequence: MAPTGQAVDVAVREGAGDVGYSVERENLPADDPVRNGNRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEHITHGYAITVHASQGTTAHSTHAVLGDNTSRATLYVAMTPARESNTAYLCERTAGEGARVDLAGWDLWVSGKAEAMSDEKSASPVWCRVGARCDHRGKRSCW
What are the official names of this protein?
Uncharacterized protein Mb2338.
Protein: SYV_DEIRA
Sequence: MTDPHTTTLPTQFDPTGIEPKWAARWRSEPFRADATSGKDPFTIVIPPPNVTGNLHLGHALDNTLIDTLIRYKRMAGFEALYLPGMDHAGISTQVVVERQLKDAGTSRHDLGREAFLEKVWEWKGKSGGMILDQLTRLGVSADWTRERFTMDEGLSRAVRTQFVKLYHDGLAYRGERIVNWDPASQTTLSELEIDREVRKGKMYTLSYKLENSAERGSNGETGEIRIATVRPETIFADQAIAVHPEDERFRHLVGQKARIPLTDRWVPIIADEAVEMEFGVGALKITPAHDPTDFEVGERHGLERPSVIDLDGNLTRDELVPAEFQGLERFAARKAVVKALEESGDLLEQKDHDTAIGLSERTKVPVEPIISEQWFVKMKPFADQVLEGLDKGEIKLVPERYTKVNRDWLENIRDWNISRQLWWGHQIPAWYDKEGNIYVPDPENPELDCDQDPRYAHLNLRRDPDVFDTWFSSNLWPFSTLGWPDTDSEDFRKFYPTQVLVTGYDILFFWVARMQMAGYGLTGQAPFSTVMLHGLYLDAKGQKMSKSKGNGIDPLELFGQYGVDACRFAFTFLSTGGQDIKHDARRFEQGRNFANKLWNATRFALMRLGEARIEGSDDLSAYVRAAVTLPDGVLLRSKDVLAQLKERDDLTLADRWIISRLNDVTAEASAQLDAFDIGAAIRTLYSFTWDEFCDWYIEAAKPELASGNLGTMATLKVVLEHVLKLLHPFMPFITSELYAALGHRRQIAVHSWPQPDAALHDAEATKAFDALRSAVDSARSLKSELGLSPQDRLNVAVDGDLADVVRQNARVVEGIARVNLVPALEGRTLSQVAPGVTILAPLEGTVDIADWVKKQQKRLAELDKQIKQAQGKLNNEGFVARAPAEVIEEEKRRVADFGAQKERLEGVLAQLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIGD_SPHSK
Sequence: MKDFQDQVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGIVLDIMDREAYARAADEVEAVFGQAPTLLSNTAGVNSFGPIEKTTYDDFDWIIGVNLNGVINGMVTFVPRMIASGRPGHIVTVSSLGGFMGSALAGPYSAAKAASINLMEGYRQGLEKYGIGVSVCTPANIKSNIAEASRLRPAKYGTSGYVENEESIASLHSIHQHGLEPEKLAEAIKKGVEDNALYIIPYPEVREGLEKHFQAIIDSVAPMESDPEGARQRVEALMAWGRDRTRVFAEGDKKGA
What is the function of this protein?
Catalyzes the C alpha dehydrogenation of arylglycerol-beta-aryl ether (C alpha alcohol type) (compound IV).
What are the official names of this protein?
C alpha-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TAL2_BACCR
Sequence: MRFFIDTANLEDIKKAYKLGVLAGVTTNPSLVAKEGVKFEDRIAEICQAVPKVESVSAEVTPDAVTAEEMIAQAEELIKINGGDKNVTIKLPMTLAGLEACRYLTEKGVKTNVTLIFTVNQALLAARAGATYVSPFLGRLDDISEDGVLLVAKIAELFDVHQLDTQIIAASVRHPDHVTRVAMAGAHIATIPYKVIEQLAMHPLTDQGIEKFAADWAKAPKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ECO45
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LIMC1_HUMAN
Sequence: MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
What is the function of this protein?
Actin stress fibers-associated protein that activates non-muscle myosin IIa.  Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9.  Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions.  It therefore negatively regulates cell spreading and cell migration.
What are the official names of this protein?
LIM and calponin homology domains-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the LIMCH1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, stress fiber.
Protein: PEAMT_SPIOL
Sequence: MAASAMGVLQEREVFKKYWIEHSVDLTVEAMMLDSQASDLDKVERPEVLSMLPPYEGKSVLELGAGIGRFTGELAEKASQVIALDFIESVIKKNESINGHYKNVKFMCADVTSPSLNISPNSVDIIFSNWLLMYLSDEEVERLVERMLKWLKPGGYIFFRESCFHQSGDHKRKSNPTHYREPRFYTKIFKECHMQDDSGNSYELSLIGCKCIGAYVKSKKNQNQISWLWQKVDSEDDKGFQRFLDSSQYKFNSILRYERVFGPGYVSTGGLETTKEFVSKLDLKPGQKVLDVGCGIGGGDFYMAENYDVEVVGIDLSINMISFALERSIGLKCAVEFEVADCTKKDYPENSFDVIYSRDTILHIQDKPALFRSFHKWLKPGGKVLISDYCKSAGTPSAEFAAYIRQRGYDLHDVKAYGKMLKDAGFVEVIAENRTDQFIQVLQKELDALEQEKDDFIDDFSEEDYNDIVDGWKAKLVRTTEGEQQWGLFIAKKM
What is the function of this protein?
Catalyzes N-methylation of phosphoethanolamine, phosphomonomethylethanolamine and phosphodimethylethanolamine, the three methylation steps required to convert phosphoethanolamine to phosphocholine.  Mediates a key step in the biosynthesis of choline, a precursor of the osmoprotectant glycine betaine.  Has no ethanolamine- or phosphatidylethanolamine-N-methyltransferase activity.
What are the official names of this protein?
Phosphoethanolamine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. PEAMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUS10_NITMS
Sequence: MTTYQKIIPIANQILKKYDLCDHCLGRLFTKQLYLSSNKLLGKKLKKNSKSSQRCYICKNLFDNLNYFLNMMIDSASHYSYSSFSVGATIKPSIIDRDDVIRSKYKLKGIDGIKTDVTKELGKLFSKKTKKSFDSLDPEIVFTVNLKDEFCDIRSKSLTLSGRYVKPVRGFLQKQKSCSNCSGKGCRICDFHGIKEFDSVEGEISQFLFKKLGGTTAKFTWIGGEDKSSLILGTGRPFFVKIQNPHKRKLRAKSANLEHIKVSNFKIVADSPKKPLKFNSSVEARISTSSIIDAKLLRKLKNLTKKPIAVYEKSGKRSEKRILSIKYKKSDETSFTLFFKFEGGLPVKRFVTGDDVSPGISQILDMSCKCLEFDFHDVEVK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: ATP6_CAMC5
Sequence: MKDLFLFSDLIYHNHLFVYAFHFCLVAIIVVLVAKLATSKMQLVPRGLQNIVEAYLEGVISMGRDTLGSEALARKYLPLVATIGFVVFFSNAIGIIPGFESPTSSLNLTLTLALIVFFYYHFEGIKKNGFFKYFGHFMGPSKALAPLMFPVEIISHLSRIVSLSFRLFGNIKGDDLFLLVMLTLAPWFAPLPAYALLTLMAVLQTFIFMMLTYVYLAGAVAIEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.