PharMolix/UniProtQA huggingface dataset:
Protein: ACOT9_BOVIN
Sequence: MRRAALRLCTLSKGLLAPSRGLTQESQNPENVFHIREVRDKLREIVGASTNWRDHVKAMEERKLLHSFLAKSQKGLPPRTMKDSYIEVFLPLGSQPELREKYLTVQNTVRFGRILEDLDSLGVLICYMHNKIHSAKMSPLSIVTALVDKIDMCKKNLSPEQDIKFSGHVSWVGKTSMEVKMHMFQLHGNDFSPVLDATFVMVARDSENKGPAFVNPLILESPEEEELFQQGELNKGRRVAFSSTSLLKMAPTAEERTTIHEMFLNTLDPKTISFRSRVLPANSVWMENSKLKSLDICHPQERNIFNRIFGGFLMRKAYELGWATACNFGGSRPFIVAVDDIMFQKPVEVGSLLFLSAQVCFTQGNYIQVRVHSEVASLQDKEHMTTNVFHFTFMSEKEVPLVFPRTYGESMLYLDGQRHFKSMSAPVTLKRNYVVEP
What is the function of this protein?
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.  Active on long chain acyl-CoAs.
What are the official names of this protein?
Acyl-coenzyme A thioesterase 9, mitochondrial, Acyl-CoA thioesterase 9, Acyl-CoA thioester hydrolase 9.
What is the protein family that this protein belongs to?
Belongs to the acyl coenzyme A hydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOF_NOSP7
Sequence: MNFEFGAKRRDPYAWLEQSLATIHRADWYRSVQPINGRPGATVVLAGQEVINFASNDYLGLAGDKRLMAAATAAIAEFGTGSTGSRLLSGHRELHRELEKAIASTKQTEDALVFSSGYLANLGAITALVGKRDLILSDQYNHSSLKNGAILSGAAVVEYPHCDVAVLKTQLSQQRQNYRRCLILTDTVFSMDGDLCPLPALFDLADEFSCMLLVDEAHATGVLGKTGAGCVEYFGCTGKQLIQIGTLSKALGSLGGYVAGSSALIDFLRNRAPSWIYTTGLSPADTAAALAAIKIVQQEPQHLAQLWRNIHYLKTLLQQLPNLKLLPSESPILCFQLPNATDALKAGKQLRDAGIFAPAIRPPTVPTSRIRISVMATHKVAHIEKLVAALKDVI
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: URK_DEIDV
Sequence: MTGHVRPFVIGVAGGSGSGKTTVTRRVIETVGGNGVSVLNQDNYYRDQSDIPFNARLNTNYDHPAAFDWPLLRSHLDALLSGVPIDMPEYDFTQHTRSAQASTVLPGAVVVLEGFFALYDEELRERMHLKVFVDADADVRFIRRLLRDTQERGRTPESVIQQYLEYVRPMHLSFVEPTKRYADVIIPHGGMNEPALDMLSARIRTTI
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_PSEPG
Sequence: MTHSNRMLLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVVVLKDVLQTRMNFEMGVTEEMMAFAEKIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLARTGAEVSLFIDADERQIEASRRVGAPAIELHTGRYADAQTPTEVAEELKRIVDGVAFGVGQGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAASR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y243_AQUAE
Sequence: MRTLSLLILFLSTFLFAQVPKELLEFFQRSGYVVEKEGEKVLIDLPRGKAFPGEIFEVFQSKKPIIHPVTKKVLGYKEEKVGEVEVIKPRENFSEAKTLENNGIKPGDRVKLKIGSVCYIGGDEGYYALSQVVQNVKRNSENCDYVVKELENGYGVSYKGKPLAFFQYSGVGFAKRGGVFEDFALKAKFVRSLESLPLSADICKLFGKKDYLVVLFSDKVKVYEVLKTDFVEVLSYAIPTGYPVGVVCYENKGRSAVLVNMISNGEASSAVLSPVGNSLMLTDKNVPYLFGFFYQNGKKVLIGQEFKGSWGKVYRFELRGDKLVRKDALNLPEDFRVDGANAWNNVLVFVDNDGQLRVYVNDEEVLTEDGFGLSYTTAEVPGVYEYAEGDKYGFYVRPNFTKVYKDVLPLIAKNRASNIFQLVGFTKFTEGELWTVVRKKEKVYEAIKLKGRKFEEAIQAIVRDSEGRIFVITGSKGTIPIQNRGEVYLIEITPL
What are the official names of this protein?
Uncharacterized protein aq_243.
Protein: SAT17_STACB
Sequence: MAASPVLATTSHPIGHEAAVVTDADLDRHYAVKLAGKLNDEMAWVGQQFTGEEDFVVCLSEADVAEVNAALTAFQDTGLKPGYLSPETFKLPKLGPKLRLLSQRIHEQEGFIVLRGLQPWRYRRLENTIVFTGIASYIGNRRGVQCADGPVMTHIFDYSTEVEEKEKLNDGYLGHANRTSYLPFHTDDGHIISLYCLQAADIGGRTLLASSHAIYNHLLETRPDVIETLKEEWIWDSFIPEKPSFIRPLLLEQDGKLICNYRIRPFLGTPGYPRNAALGPLPAHQEEALNTVAEIAEKLSLKFEFKTGDIQFLNNLSILHAREEFHCAKGDTTRRHLLRLVQMDDELAWRLPPGLSKDMDKMFQHDLEEEKFIWSPEPLPYVIGQ
What is the function of this protein?
Taurine hydroxylase-like protein; part of the satratoxin SC3 cluster involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings (PubMed:25015739).  Satratoxins are suggested to be made by products of multiple gene clusters (SC1, SC2 and SC3) that encode 21 proteins in all, including polyketide synthases, acetyltransferases, and other enzymes expected to modify the trichothecene skeleton (PubMed:25015739).  SC1 encodes 10 proteins, SAT1 to SAT10 (PubMed:25015739).  The largest are SAT8, which encodes a putative polyketide synthase (PKS) with a conventional non-reducing architecture, and SAT10, a putative protein containing four ankyrin repeats and thus may be involved in protein scaffolding (PubMed:25015739).  The putative short-chain reductase SAT3 may assist the PKS in some capacity (PubMed:25015739).  SAT6 contains a secretory lipase domain and acts probably as a trichothecene esterase (PubMed:25015739).  SAT5 encodes a putative acetyltransferase, and so, with SAT6, may affect endogenous protection from toxicity (PubMed:25015739).  The probable transcription factor SAT9 may regulate the expression of the SC1 cluster (PubMed:25015739).  SC2 encodes proteins SAT11 to SAT16, the largest of which encodes the putative reducing PKS SAT13 (PubMed:25015739).  SAT11 is a cytochrome P450 monooxygenase, while SAT14 and SAT16 are probable acetyltransferases (PubMed:25015739).  The SC2 cluster may be regulated by the transcription factor SAT15 (PubMed:25015739).  SC3 is a small cluster that encodes 5 proteins, SAT17 to SAT21 (PubMed:25015739).  SAT21 is a putative MFS-type transporter which may have a role in exporting secondary metabolites (PubMed:25015739).  The four other proteins putatively encoded in SC3 include the taurine hydroxylase-like protein SAT17, the O-methyltransferase SAT18, the acetyltransferase SAT19, and the Cys6-type zinc finger SAT20, the latter being probably involved in regulation of SC3 expression (PubMed:25015739).
What are the official names of this protein?
Taurine hydroxylase-like protein SAT17, Satratoxin biosynthesis SC3 cluster protein 17.
Protein: GLGC_RHOE4
Sequence: MRSQPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNAGYLRICVLTQYKSHSLDRHISQTWRLSGFAGEYITPVPAQQRLGPRWYTGSADAILQSLNLVYDEDPEYIVVFGADHVYRMDPEQMVQHHIESGAGVTVAGIRVPRSEAFAFGCIDSDESGRITQFLEKPAHPPGTPDDPNSTFASMGNYVFTTKVLVDAIRADSENSDSDHDMGGDIIPALVAAGEASVYDFKDNVVPGATDRDRGYWRDVGTLDAFYDAHMDLVSVHPIFNLYNRRWPIRGATENLAPAKFVKGGLAQESVVGAGSILSAATVRNSVLSSNVMIEDGATVEGSVLMPGVRIGKGAVVRRAILDKNVVVGDGEIIGVDLERDRERFAVSQGGVVAIGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: LIPL_RAT
Sequence: MESKALLLVALGVWLQSLTAFRGGVAAADGGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWLEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAEKGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTENDKQNNQAFEISLYGTVAESENIPFTLPEVATNKTYSFLIYTEVDIGELLMMKLKWKNDSYFRWSDWWSSPSFVIEKIRVKAGETQKKVIFCAREKVSHLQKGKDAAVFVKCHDKSLKKSG
What is the function of this protein?
Key enzyme in triglyceride metabolism (By similarity).  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (By similarity).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells. Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non- coated endocytic vesicles.
Protein: KUP1_LACLS
Sequence: MGYQHNRSFNKATGAGFIIAMGIVYGDIGTSPLYTMESIVQGQGGLERISETSIIGALSLIIWTLTLITTVKYVWIALKADNNHEGGIFSLFTLVRKYAKWLIIPAMIGGAALLSDGALTPAVTVTSAIEGLRSIPAFHEAFGQQQLPIVIITLAILAILFLIQRFGTSIVGKVFGPVMFIWFSFFGITGLINLFGDFSVLQAINPYWAIHLLLSPENKAGIFVLGSVFLATTGAEALYSDLGHVGRGNIHVSWPFVKVCIILSYCGQAAWLLQNRGKSLGDINPFFAVLPQSLIIFSVILATLAAIIASQALISGSFTLVSEAIRLKLLPRLRINYPGESFGQLYIPAVNLGLWLAASFIVVYFQSSAHMEAAYGLAITVTMLMTTILLTVYLAQHQKVKKVFVVLFFGAFIFIEGLFFAASAVKFLHGGYVVVILAALILFVMAIWHKSDQLFYKYLKSSNLNDYKEQMNKLRKDESYDLYHTNVVYLTAKMDKEWIDRSILYSILDKRPKKAEVYWFVKVNVTDEPYTSEYEVDMLGTDFIVCVNLYLGFHMRQEIPRYLRTIVTNLMESGRLPQQHQPYSIIPGRKVGDFRFILLEEKLINARQMPAFERFVLQTKEQIKKITASPARWFGLHFSEVTVETVPLVLSDVRNLEIHERISKENEVENLSK
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METXS_AZOSB
Sequence: MTEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSHHVAGVYADDPRNVGWWDNLVGPGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWGADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQALSWTLQYPERVGHAAVIASAPKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEKFGRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNLNAALARASADFLVVSFTTDWRFSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDPQYHALLSAWFDRIEV
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_PYRIL
Sequence: MKCIDRRLIGDLIALSTVEGLSVTDAAEKLCLTRQGLYKLLRHLKKEGYVAEGPAIRLTQKGKDTLGIVLKDLLRYFNILSIRLSGRVVSGLGEGAFYMSLEGYRRAIEQKLGFTPYPGTLNIKLDPPSVVYKRYLDSLPGILIPGFSNGLRTYGAVKAFRAKLRDIEGAIVMPERTHHPTDVIEVIAPFKLREILGLRDGDRVEIEIYLE
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: NIKR_METKA
Sequence: MNKGEDNLVRTSITVPEQLLQKVNELIASGYFASRSEIFRQALREYLQRIEWTERVGDEEYFGALTYVFQHERAEPELVKVQHEFTDVIISTTHIHVSPEKCLEVLLLQGPGKRIAELAKRIRGVRGVEQAKLTVVSSEGE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: CRCB_HAEIG
Sequence: MQALLFISCGAILGASLRWAIGLLFNPLFSSFAFGTLIANLFGCLIIGVLLGLFWQFPQISSEWRLFLITGFLGSLTTFSSFSSEVVELFFNDKWLNGFCVLMMHLFGCLAMTVLGIWIYKICSQLLS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_LISMF
Sequence: MGEIIDGKKLAKEIQEKVTREVAELVKEGKKPGLAVVLVGDNQASRTYVRNKQKRTEEAGMKSVLIELPENVTEEKLLSVVEELNEDKTIHGILVQLPLPEHISEEKVIDTISYDKDVDGFHPVNVGNLFIGKDSFVPCTPAGIIELIKSTGTQIEGKRAVVIGRSNIVGKPVAQLLLIENATVTIAHSRTKDLPQVAKEADILVVATGLAKFVKKDYIKPGAVVIDVGMDRDENNKLCGDVDFDDVVEEAGFITPVPGGVGPMTITMLLANTLKAAKRIWKMN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YR198_MIMIV
Sequence: MNKKKITKIVNDIIAEIDLNYLIAEAVKNNYDLILVYGKLDTTIEWSTNTYHLPCNYELAVSVLHYFIGKYMDKIIKLKSVSKFDCVYGLNRNTIIYVPYEYDIELIRKQYYNTL
What are the official names of this protein?
Uncharacterized protein R198.
Protein: TGT_STRT1
Sequence: MIDFPIKYRLIKKEKYTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELQQMGSGIILANTYHLWLRPGDELIAKAGGLHKFMNWDQAILTDSGGFQVYSLAEKRDISEEGVTFKNHLNGSKMFLSPEKAISVQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSSHDLVSMDFPGYSIGGLAVGETHEEMNAVLDFTVPLLPENKPRYLMGVGAPDSLIDGVIRGVDMYDCVLPTRIARNGTCMTSNGRLVVKNAAYAEDFSPIDPECDCYTCKNYTRAYVRHLLKADETFGIRLTSYHNLYFLVNLMARVRQAIVDDNLLEFRQDFIEKYGYNASNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: Y359_AQUAE
Sequence: MLLDRYLLSRFLGIFLNVSFVSVLLVSLYALLDFLVGFKEKRTDVALSYFLNILPLGFYYISFITLSISLILFLRKVFEKKMELTVQSFGISPLRFSLPVLLFSVFLSSTFLLGNEYAFPKLLGNLWFIEKNYKKKQEVKGFIKNFWFIKKENEVKTYYHVGNLNLSDGSLFNFYTMKVERKNLNPLEVLKVFSGVWKDKEIFIRSGEIYDFEKGKREKVFNKTFKLGLSIKEVELFSEKIDFLSLSEIFFLMQKSKKVGLNVDVYTGELFYRVMFSLSPVFISIFSLYLFFKHKVLSQVIPRFLVFIVILWLVILSPKILPQKANQPVLYSLIPIFLLILYSLKGVYDLRKGFRV
What are the official names of this protein?
Uncharacterized protein aq_359.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NANK_ECOLI
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEFQALDGDITDMVFITVSTGVGGGVVSGCKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.  Has also low level glucokinase activity in vitro.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: DXR_CHLMU
Sequence: MKRLALIGSTGSIGKQVLQVIREIPDAFVIETLAAYGRNRESLISQIREFSPRVVAVRDETTYKELRKLFPHIEILSGEEGLIAVATAASVDMTIVASSGIDALPAVMASIQERKTIALANKESLVAAGELVTTLAKKNHVQILPIDSEHNALFQCLEGRDPSTIKKLILTASGGPLRNKSKEELQKVTLQEVLKHPIWDMGPKITVDSSTLVNKGLEIIEAFWLFGLQAVEIEAVIHPQSLIHGMVEFCDGTILSVMNPPSMLFPIQHVLTFPDRYPSIISGLNFLTNQTLEFLPIDDERFPSIRLAKDVLREGGSMGCFFNGANEALVQRFLSGEIAWYQIVSKLQTLMDKYVVRSCLSLEDILQVDSEARALASEC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS16_CAUVC
Sequence: MLKIRLARGGAKKRPYYSIVVADSHSPRDGRFIEKVGTYNPLLKKDDANRVTLKVESIQEWLKKGAQPTDRVARFLAAQGLVAWTHGNNPEKGKPGKKAQERLAERAQREEERKQAEADAKAAAEAEKAAAAEAAAAAAAAPAVEEAPAEEAPAAEAPAEEAAEG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: C3H56_ORYSJ
Sequence: MDYTNAIHIIPDAAGPDAWANAAAQGGDAGIWATEDDYNSQWNADGGGGGSSRAGSEQPPPGKKSRGGGGGEGGGNTSKSRAIGKMFFKTKLCCKFRAGTCPYVTNCNFAHGMEELRKPPPNWQEIVAAHEEATEAREEHQIPIMTSSGPTAGGDAGCGGGGGGGSGRAYKGRHCKKFYTDEGCPYGDACTFLHDEQSKARESVAISLSPSVGGGGGGGSYNSAAAAAASASAAAGNGPMQKPSNWKTRICNKWEMTGYCPFGSKCHFAHGAAELHKYGGGLVDIDSRDAAATPDSKQAVVSAKAPAETAAASTTVLPHADVYHLGVQAQRSTIAGQRSGQVQRPIQKWKGPDKISRIYGDWIDETE
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 56, OsC3H56.
Protein: Y019_BACP2
Sequence: MEKHNHYFYVLKCADGSLYAGYTNDLQKRLMTHNSGKGAKYTRARRPVELYYHECFATKREAMQQEYRFKTWTRKKKDLYIEEMRIEKEATHEHTKKL
What are the official names of this protein?
UPF0213 protein BPUM_0019.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: SRK2_SPOLA
Sequence: TFLVRESESKPGDYSLSIQDGDNVKHYRIRKLDEGGFFITRRAVFNTLKDLVQYYQNESDGLCVNLRQPCRPLERPQIDLSHKTKDMWEISRDSITLIRKLGAGQFGEVYQGLWNNSTPVAVKTLKAGTMQPAAFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELHNYIHRDLAARNILVGDNNICKVADFGLARLIVSDDYNATEGAKFPIKWTAPEAALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVLQNLDKGYRMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQWRLEDFFVLDAGQYQHAADVL
What are the official names of this protein?
Tyrosine-protein kinase SRK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR48_MACFA
Sequence: MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWVSVKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
What is the function of this protein?
Regulator of deubiquitinating complexes, which acts as a strong activator of USP1, USP12 and USP46.  Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself.  Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate.  Also activates deubiquitinating activity of complexes containing USP12.  Docks at the distal end of the USP12 fingers domain and induces a cascade of structural changes leading to the activation of the enzyme.  Together with RAD51AP1, promotes DNA repair by stimulating RAD51-mediated homologous recombination.  Binds single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA).  DNA-binding is required both for USP1-mediated deubiquitination of FANCD2 and stimulation of RAD51-mediated homologous recombination: both WDR48/UAF1 and RAD51AP1 have coordinated role in DNA-binding during these processes. Together with ATAD5 and by regulating USP1 activity, has a role in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA.  Together with ATAD5, has a role in recruiting RAD51 to stalled forks during replication stress.
What are the official names of this protein?
WD repeat-containing protein 48, USP1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR48 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Lysosome. Late endosome. Note=Mainly in cytoplasmic compartments.
Protein: ATPF_SYNJB
Sequence: MPVWSWVAGWILAVAETTELLPEAKAGEGDLLAKILESNLINIAIILTLLFILGRKVVGEALAKRREGILEELRQAEQRKREAIERLAEEQQKLAQAQQEAERIRKQAEANAEARRQELLEQAEREVERLRANAEKELSSEQERVFQELRRQIVRQALSKVEQELPQHLNEEVHRSLIEKGIQMIAR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ADD_SHEPW
Sequence: MNYLNLPKIDLHCHLDGSVRPQSVIDIALQQNITLPSNDLSEIQSLMVAPDTCLNLDEYLTRFELPLSVMQTAAGIERIAFEVFEDAAIENVKYLEVRFAPLLHLQSGLTLQQVIGSAVKGMKRAEAQHDIKGNFILSIIRNMPKDRVNEVIDAGASFINNGVVAFDLAGSELPGFCEGFIPHAKYAVEKGYRVTIHAGEQGVGQNVHDAIAMLGAERIGHGIGINAHKQAYELTKSESVALETCPTSNVQTKAVDSLSSHPFREFYKDGVLITINTDNRTVSNTTMTDEVRKVMQEFDLSREEYFEIYKVSVEHSFASDAVKQQLLALAE
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.