PharMolix/UniProtQA huggingface dataset:
Protein: URE2_PSEU2
Sequence: MIPGQYQIQPGDIELNAGRRTLSLTVANSGDRPIQVGSHFHFFETNDALTFDRAASRGMRLNIPAGTAVRFEPGQSREVELVDLAGLRKVYGFAGRVMGEL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEDG_ASPTN
Sequence: MSVDTANPTSPMMETHEQIFAQDPDFWKNYRRGRPQVPYSFFQRIYNYHQGHSGRFETVHDAGAGNGVYSKELRSKFHHVIVSDVVAENVRQAEERLGTEGYSFRVGKMEELDEIPAASVDMVFVMNAMHWADDQTRAMRAIAAQLRPGGTFACAGFGPARFRDARVQDVWERISQQGGRLLLQTANQPVDTINVMVRSQDHYNVAPLDERLFRQRALRIYLNQETGGLTGLLPPERRGEVTEPDHEGPHDQITFEHDDEWRFDMDLDGFKEHFRTFPHAFRDPEAFTSLWQEIEELVRQGSRLDGAWPVTLILATRTNA
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodinanthrone (PubMed:24009710).  The next step is performed by the emodinanthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Ring cleavage of questin by questin oxidase gedK leads to desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by methyltransferase gedG leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Methyltransferase gedG, Geodin synthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: CP51_CUNEL
Sequence: MAIVSQISRFITFTIISMGYSVLAVGVALTIHILSQLIVPKNPNEPPNVFSLIPVLGNAVQFGMNPVAFLQECQKKYGDVFTFTMVGKRVTVCLGADGNQFVFNSKQNLSSAAEAYNHMTKYVFGPDVVYDAPHAVFMEQKKFIKAGLNSDCFRQHVPMIVQETEEFFKKFNKPTGFIEAYETFGSLIIYTASRCLMGKEIRASLDGNVAKLYYDLDQGFKPINFIFPNLPLPSYRRRDVACKKMADLYSSIIQRRKDEKDNNNADLLQALMDATYKDGTHIPDHHIAGMMIAVLFGGQHTSATTSAWTILELANRPDIIKALREEQIEKLGSLKADLTFDNLKDLPLLEAAIRETLRLHPPIFQMMRRVVADKIVYEKNGMEIPKGNFICAAPGVTQVDPTYFNEPTTYNPYRWIEKTDPVHQLEQGDDANIDYGFGAVGISSKSPFLPFGAGRHRCIGEQFGYLQLKTVISTFIRTFDFDLDGKSVPKSDYTSMVVVPEHTAKVRYTWRE
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in fungal membranes that participates in a variety of functions (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane (By similarity).  In filamentous fungi, during the initial step of this module, lanosterol (lanosta-8,24-dien-3beta-ol) can be metabolized to eburicol (By similarity).  Sterol 14alpha-demethylase catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of both these sterols in the form of formate, and converts eburicol and lanosterol to 14-demethyleburicol (4,4,24-trimethylergosta-8,14,24(28)-trienol) and 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, respectively, which are further metabolized by other enzymes in the pathway to ergosterol (By similarity).  Can also use susbtrates not intrinsic to fungi, such as 24,25-dihydrolanosterol (DHL), producing 4,4-dimethyl-8,14-cholestadien-3-beta-ol, but at lower rates than the endogenous substrates (By similarity).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: YIRD_SCHPO
Sequence: MDLEELQKIIQEEQIRCEREIAEAAEARNSSNSLIVVDEYSKESEDVLENGLEHVQSNEFTESEDYKSIERSLAVTEAVMARFEKEMGSLRDQMNFFHQILDNDNLDGFLTGSSKPC
What are the official names of this protein?
Uncharacterized protein C664.13.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IOLG_LEIXX
Sequence: MTTTPDLRVGVGGAGQMGADHIQRITRVISGATVSAIVEPDAGRAAAAAAAPGSRAFASLDDALDASALEAVVIATPGQFHELVLVPALAAGLPVLCEKPLTPDSAEALRVLELEQTLDRPHIQLGFMRRFDDEYRALRELVVSGDAGELLFLRGVHRNPSVPESYTQSMLITDSVVHEFDVMPWLAGSPVASVEVKYPRRNDRAPERLREPILVLIELRNGVLVDVEMNVSVRFGYQVATEAVFQTGTARIGQPAGLQRWSDARFSIAEHTSFTTRFARAYDAQVQAWVDAVRDGSLVAGPNAWDGYLVALACEAGVRALSEPGPIAFAPAERPAFYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SYGB_IDILO
Sequence: MQKENLLIELGTEELPPKALKSLRDSLKSGIESGLKNAELSFDSIEAYATPRRLAVLVKQVETEQQDKEVEKRGPAINVAFDDTGKPTKAAEGWARSNGITVEQADRLKTDKGEWLLHKATVKGQALSVLVQGILEAAIKALPIPKPMRWGDSTAQFIRPVHTLTVMLGSELIDAEILETKSARFIQGHRFHSPQGFELDHVDNYLFKLREAKVIANFEERIETIQSEVSRLASELGGQVIQDDELVEEVAALVEWPVALTASFDQGFLAVPKEPLIVTMKDDQRYFPVEDGKGNLLPQFIFITNIESRDPQQIIKGNEKVVRPRLADAQFFFESDKKVTLESRVAALDSVLFQKQLGSIGDKARRISVLAGKIANQLTADVKASERAGLLCKADLVSDMVSEFPETQGVMGKHYALNDGESPVVAEAIEQHYWPRFSGDELPLTKEACAVALADKLDTLVGIFGIGQVPKGDRDPFALRRAALGLLRTLVERKLSLDLHELLAASVEGFGDKLSNNTVATDVFDFLLGRFRPWYQDQGITVDVIQSVLARSPSKPTDFDQRVKAVQSFKSMDSAASLAAANKRVGNILAKSDEEISGNVDEALLQEESETTLYRLVKQTEGAVKPLIAAGKYSDALTHLSELKEPVDAFFEHVMVNADDDKVRINRLNLLFRLRQLFLEIADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_ECOL5
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HRH2_HUMAN
Sequence: MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
What is the function of this protein?
The H2 subclass of histamine receptors mediates gastric acid secretion.  Also appears to regulate gastrointestinal motility and intestinal secretion.  Possible role in regulating cell growth and differentiation.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
What are the official names of this protein?
Histamine H2 receptor, H2R, HH2R, Gastric receptor I.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y396_CLOBJ
Sequence: MRIGFDHEKYLEEQSKYILERVNNYDKLYLEFGGKLLFDLHAKRVLPGFDENAKIKLLHKLKEKVEIIICLYAGDIERNKIRGDFGITYDVDVLRLIDDLRGYDLEVNSVVITRYSGQPATNIFINKLERRGIKVYKHEATKGYPTDVDTIVSDEGYGKNPYIETTKPIVVVTAPGPGSGKLATCLSQLYHEYKRGNVAGYSKFETFPVWNVPLKHPLNIAYESATVDLKDVNMIDSFHFDAYNKVAVNYNRDIESFPVLKRIIEKITGEESVYKSPTDMGVNRVGFGIVDDEIVKEASKQEIIRRAFKTACEYKKGYVDKETFHRAKLIMEEMNLKEEDRKVVIPAREYAAKLKERANKSETCTVVALELEDGTILTGRSSELMDGTAAVILNAVKHYANISDEIHLISPVILEPIINLKAKTLGSKRTALSCEEVLIALSICAATNPTAQVAMGKLPMLKGCQAHSTTILSTNEEQTFRKLGIDVTCDPEYISESLYYNN
What are the official names of this protein?
UPF0371 protein CLM_0396.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: ATPA_PSEE4
Sequence: MQQLNPSEISEIIKGRIEKLDVSSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGSVFGMALNLEQDSVGAVVLGDYTSLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPIDGKGPLNNTETDAVEKVAPGVIWRKSVDQPVQTGYKSVDAMIPVGRGQRELIIGDRQIGKTAMAVDAIINQKNSGIFCVYVAVGQKQSTIANVVRKLEEAGALANTIVVAASASESAALQFLAPYAGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNAGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMALSLYAAERGFLTDVEVAKVGSFEQALIAYFNRDHAELMAKINVKGDFNDEIDAGMKAGIEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CFI1_ARATH
Sequence: MSSSNACASPSPFPAVTKLHVDSVTFVPSVKSPASSNPLFLGGAGVRGLDIQGKFVIFTVIGVYLEGNAVPSLSVKWKGKTTEELTESIPFFREIVTGAFEKFIKVTMKLPLTGQQYSEKVTENCVAIWKQLGLYTDCEAKAVEKFLEIFKEETFPPGSSILFALSPTGSLTVAFSKDDSIPETGIAVIENKLLAEAVLESIIGKNGVSPGTRLSVAERLSQLMMKNKDEKEVSDHSVEEKLAKEN
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
What are the official names of this protein?
Chalcone--flavanone isomerase 1, Chalcone isomerase 1, Protein TRANSPARENT TESTA 5.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: YBJ2_SCHPO
Sequence: MMSNENFDNDYNLPPPNDSAEDLKIFIERYERSVDSTLLEIDENKREALEKNILRKDRKMKYEIECNERLQGWKKLAIEREISEEQSGEVQFPRWIDEWANTKLGGIFERIFSKMDSMQNDMNSRFDAMQNEMTSMKGEMAEMKVEMVEMKRETIRLNTRIDLLEQKTEARFQSIEQRFNSIDQRFDSMEQRLDSMDQKMETIDARSCRSIMLTRKLENATRSDQGYLASPVPFLNGNEPVSSGLPPIERVEDIDELSKEQCVQYLKGYGITFSPAETIKLKKRLRDTVGLWSKASTEYEFHQFH
What are the official names of this protein?
UPF0612 protein C337.02c.
What is the protein family that this protein belongs to?
Belongs to the UPF0612 family.
Protein: YIDD_BACSU
Sequence: MKTLFIALIRGYQKFISPLTPPTCRFYPTCSQYGIEAIKTHGALKGGWLTIKRILKCHPFHPGGVDPVPEKKQKH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSCB_RICPU
Sequence: MQNYFQLLGLPQKYNINLKILEKQYFAMQVKYHPDKAKTLQEKEQNLITAAELNNAYSTLKDALKRAEYMLLLQNINLNDEKTRSLLSPLELSIFWDEMEIIENTILFSDLEKIKDKYELMKKLEIDSLKQAFEEQNLSDATIKTSKLKYIGTLLHKLQEKIKSCK
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: BIPC_BURM7
Sequence: MSIGVQSSGINISHAELSRLVDAGKSEQGDKAVRDDGRALARADAALAAVVGERVAARRDAVAGSGAQRVELARPKPDAQTRATDRRTVSGLEREHKRLAASQTPRVTGMHDALVQRHVSLDGAKAAHGEGVKRAAGDAPRAAADAPQRFAFADDKAFDAMLALGAAMQKNVQSDLAMQGKLTMLAHDAMMSAAAQDRSIGAAQMTAAIAGGALQATTSLGGAMQQMKSLSTKSMSIEKELKPQAELKQFHAEQALELRGINKPVLSNDEVSHVKIKRDTGETVRHEIDHGGERMSDEHASVLAQEAPARQHRIDMHGMRHEENLVKAGRQQMKGDLLQSGGQIGKNQIDGASAQQQGADRAEQKEDENAQQTAMAAASTRDEAAHRSREAAQKAIDAAKSQVANDNAVAAQVAGNLRT
What are the official names of this protein?
Effector protein BipC.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: KV6AB_MOUSE
Sequence: QILLTQSPAIMSASPGQKVTMTCSASSSVSYMYWYQQKPGSSPRLLIYDTSNLASGVPVRFSGSGSATSYSLTITRMQAEDAATYYCQQWSSYPPMLTFGAGTKLELK
What are the official names of this protein?
Ig kappa chain V-VI region NQ2-6.1.
Protein: RL362_RENSM
Sequence: MKVKPSVKQICDKCKVIRRNGRVMVICENPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CLPP_LEPVR
Sequence: MPIGVPKVPFRSPGEGDTSWVDIYNRLYRERLFFLGQDVDTEISNQLISLMIYLSIEKDTKDLYLFINSPGGWVISGMAIYDTMQFVRPDVQTICMGLAASIASFILVGGAITKRIAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYVQRTGKPIWVVSEDMERDVFMSATEAQAHGIVDLVAVQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: QUEF_ACAM1
Sequence: MSQSPIQNPTSDPNAQSVQETSESKYGERQIAEGTLITFPNPRVGRRYDIHITLPEFTCKCPFSGYPDFATIHLTYVPDQRVVELKALKLYINSYRDRYISHEESVNQILDDIVAACDPLEITVKGDFLPRGNVHTVIEVHHQK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAT1_TRYCC
Sequence: MSSTSQVALLPKLSLPDGVTVWDGTALEYERRCNNVDEHAVHLMQTINILGIRSKEAQCLNTVLTSVARLRENRQARVYLLCQDGYGVGILKMGVKKLFVTHPSYSSLVEIDPLCVLDFFVDTSFQRKGFGKTLFDAMLLNEGLNPGEVAIDRPSVKFLAFLQKYYGLVEYTPQSNNFVVFHRYFDKWQPQRGKGHWGGNAVPTRSLVRPQNCLRVYPKYQSTTGPNNNFEEDATHRTPPPPPLPPPLVPQGSVTSPGVGKKTAYELQYEEYLREQAYRRRQGGDPRLQPVPNPVSSSEIVAASCGARRRMSPTRSGVQYNIISGTPEH
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT 1, TAT 1, Acetyltransferase mec-17 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: XYLA_PSECP
Sequence: MTLSPTTADKFTFGLWTVGWTGADPFGVATRAALDPVEAVHKLSELGAYGITFHDNDLVPFDAPASERELILKNFRAALADTGLKVPMVTTNLFSHPVFKDGGFTSNDRSVRRFALSKVLRNIDLAAELGAETFVMWGGREGSEYDGSKDLAAALDRMKEGVDTAAGYIKDKGYNLRIALEPKPNEPRGDIFLPTVGHGLAFIAQLEHGDIVGLNPETGHEQMAGLNFTHGIAQALWAGKLFHIDLNGQRGIKYDQDLVFGHGDLTSAFFTVDLLENGFPGGGPKYDGPRHFDYKPSRTDGYDGVWESAKANMAMYLLLKERALAFRADPEVQEALAASGVFELGEPTLNAGETTADLLADAASFEDFDADKAAERSFAFVRLNQLAIEHLLNAR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF1_CANAL
Sequence: MNDTWRSRLKEISHITADPFLRDFHKLHTNDKEQIYSILHNPDNVVEQTFKNTIIKSMEESMFRPLIPTQQMKRRQNDHHNQGPPPKVQKSTVDSLKSQHQIDQQNLDWFLSQPLEDLEVMTVPEQYPLTVPAVLPLAELYYLTQTLASIKLLPGSHKVLMTENFESALAEGKIAVLYSRIEELKRQGKWSLRQPQKFYDPFKFIRKSKKKSFHWDYLLQEGKWMADDFRESSKYKKWCCVVIAEAVEQYWKGRKVSHQTFVDVADLKKIDKSIIRNLPVYTGLGGDSREPPIATVSKLVYPAEDNHWYKIALKPHHHHHRHQTTHQGLFGSTRKYNTLKPPKPPTPKNIEYRIPTIWLPEDDKRLIHYVAEFCFNWDLISEHISSSSTAVSLKKYESNIERRTPWQCFERYIQLNDKFQFSDMKGVYAYHAQQWLEQAHRAQSTTKRRISPLGVGPESVQRGNRKLRWASMFDAMRKAMKKREIAAAKVNHRKSTAELQANQNVTEPKPNSDRIPTPAELSRLKFERDKTLHENHINQQATRARMVQAVAKPAPAPAPAPPPPPPPKPVKRPTTPNGTPLTNEQIQHLLQMQKHRRMLQQQQQQQQQQQHQQQQRRIHFPPAQVSKVINDIQQQNPGLSKDQVTKLAAQYLASLSQQGYGVPSSPVPPHQKNQTASPMSGSPNNA
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SURE_LEPIC
Sequence: MNILITNDDGIASSGIKALETILQKEHNTYLIAPLRERSATSMALSIYDSMRVERINDNHYIVDGYPADCVNIGLHGEIFPKIDLVLSGINRGVNMGHDVHYSGTVGAARHGAIHKKLSLAVSSGNIAKDYDYIREAEFVRKFINEYSSQLKVGVVYNMNIPSDFISSMENLRVTKLGKRTYEDTYSQKNIIGGIADFYLGGSELGHSTEEGTDFTAFFSGKISLTPLSLDQTDFSILTQLSDSLSKNIS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_FRATN
Sequence: MTQIMTPKTIVHELERHIIGQNDAKKAVAIALRNRWRRMQLDNEMRQEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKDVESIIRDLVETAVKMKREEAKEKVTEKAARLAEDRILDVLIPPARTSESKVGFANEPAEDAASKKEKENKTREIFRKKIQKGELDDKEIEIEVAVAPKTIGVMGPPGMEDMTSQLQDLFSSLSTDKKKNKKMRIKDAIKLAQDEEAAKLVNEEDIKARALEAVEQNGIVFLDEIDKVCRKSSNSGADVSREGVQRDLLPLVEGSTVSTKYGMIKTDHILFIASGAFHVAKPSDLIPELQGRLPIRVELKSLEIEDFVRILREPDCSILKQYIALMKTEGVDLSFEEDAIRKIAEIAYKVNEEVENIGARRLHTVMERLLEEISFDAPELVEKNINITTDYVNEKLGNLVKNKDLSQYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_PARMW
Sequence: MIQQESYLSVADNSGAKRIQCIRVLGTNRRYAHVGDVIVAAVKDAMPNMGVKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIINADNNPKGTRVFGPVARELRERNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SQD2_ARATH
Sequence: MTTLSSINLSIPPHLLPSTTNTCSSSSATSCSPPRSSSFVLHSPLSFGHRRLPISKKSKLRFCGVITKEAVSGSNDMTITQVREDDESEIDAPLLDPESLSKPRRIALFVEPSPFAYVSGYKNRFQNFIRYLREMGDEVIVVTTHEGVPEEFYGARVIGSRSFPCPYYQKVPLSLALSPRIISEIARFKPDIIHASSPGVMVFGALAIAKMLSVPIVMSYHTHVPVYIPRYTFSWLVKPMWSIIRFLHRAADLTLVPSAAIGKDLIAAGATAANQLRLWNKGVDSESFNPRFRSQEMRIRLSNGEPEKPLVIHVGRIGVEKSLELLKSVMDKLPEARIAFIGDGPYKEDLEKLFTGMPAVFTGTLQGDELSQAYASGDVFVMPSESETLGLVVLEAMSSGLPVVAARAGGIPDIIPEDQEGKTGFLFNPGDVEDCVTKLRTLLHDRETREIIGKAAREETEKYDWRAATTKIRNEQYSAAIWFWRKKKVHVLGPINWLIKRLFPVPEGNV
What is the function of this protein?
Catalyzes the transfer of the sulfoquinovose moiety from UDP-sulfoquinovose to diacylglycerol during sulfolipid biosynthesis (PubMed:11960029).  Sulfolipid contributes to maintaining a negatively charged lipid-water interface, a requirement for proper function of photosynthetic membranes (PubMed:11960029).  Sulfolipid may also function as a substitute of anionic phospholipids under phosphate-limited growth conditions (PubMed:11960029).
What are the official names of this protein?
Sulfoquinovosyl transferase SQD2, Protein SULFOQUINOVOSYLDIACYLGLYCEROL 2, Sulfolipid synthase SQD2, UDP-sulfoquinovose: diacylglycerol alpha-sulfoquinovosyltransferase SQD2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: TRHO_STAS1
Sequence: MDYRVLLYYKYTTIDDPELFATEHLAFCKDLELKGRILVSTEGINGTVSGTVEATDKYMEALKNDARFQGITFKVDEAEGHAFKKMHVRPRQEIVALDLEDDVNPRELTGNYLSPKEFREALLSDDTVVIDARNDYEYDLGHFRGAVRPDITRFRDLPDWIKENKEQFMDKKIVTYCTGGIRCEKFSGYLLKEGFEDVSQLEGGIATYGKDPETKGEFWDGKMYVFDERISVEVNHVDKTVVGKEWFDGTPCERYINCSNPECNKQILVSEENEARYLGACSHECAKHENNRYVKKHNISDEEKAKRLENFKELVK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CSPD_ECOLI
Sequence: MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
What is the function of this protein?
Involved in persister cell formation, acting downstream of mRNA interferase (toxin) MqsR.  Overproduction is toxic.
What are the official names of this protein?
Cold shock-like protein CspD, CSP-D.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_PYRFU
Sequence: MGKVHRPRRGSLGFSPRKRAKSIVPRIRSWPKETEVRMLGFAGYKAGMTHILMIDDEPGLTNGKEIFMPVTIIETPPLRVFGIRAYRMGYLGLETATEVIVPDFPLDNYPAKERKGKPKPKMTFYKLLERRIATLPKNYTQEMFEQKLGQLEDMIKEGEIVDVRAIVATQPWVIKLKKKPEVMEYAIGGTSVEEKFNYIKEKLGKELRVGEVLKEGELLDVIAVTKGKGTQGPVKRWGIKLRAHKDSKGRRKVGSIGPWHPARVMWTVPMAGQMGFHHRTELNKRLIAIGENGKLKLDENTEIEITPKGGFPHYGIVRSDFMMIAGSVPGAIKRIIRVRPAIRPPKKKPPVQRPQITYVSVESKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, Large ribosomal subunit protein uL3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.