PharMolix/UniProtQA huggingface dataset:
Protein: RBL2_RAT
Sequence: MASGGNQSSPPPPAAAASSEEEEEDGDTADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGVSEDGHPRDSHPSSDPPCVIEKLCSLHDGLVLEAKGIKQHFWKPYIRKLFEKKLLRGKEENLTGFLEPGNFAESFKAVNKAYEEYVLATGSLDERIFLGEDAEEEVGTFSRCVSAASGTESAERTQMRDILQQHLDKSKTLRVCNPLTGVRYVQENSPCVTPVSTATHSLNRLHTMLAGLRNAPSEKLEQILRSCSRDPTRAIADRLREMYEIYSQHFQPDENVSNCAKEMANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEQDAFHKSLLACCLEVVAFSYKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVTPPHNLERTDEIYIAGSPLTPRRVGEVRTDAGGLGRSVTSPTTLYDRYSSPTVSTTRRRLFESDSPSEGSTAGRIPPQPLVNAVPVQNVSGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVTGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNQGQPLTSSSIRPRKTSSLSLFFRKVYYLAGVRLRDLCTKLDISDELRKKIWTCFEFSIVQCPELMMDRHLDQLLMCAIYVMAKVTKEDKSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSCENRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGANSDIEEEERGDLIQFYNNIYRKQIQTFAMKYSQANSQMDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHKNEAMLSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSH
What is the function of this protein?
Key regulator of entry into cell division.  Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.  Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression.  Controls histone H4 'Lys-20' trimethylation.  Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.  Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5.  Binds to cyclins A and E.  Binds to and may be involved in the transforming capacity of the adenovirus E1A protein.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Retinoblastoma-like protein 2, 130 kDa retinoblastoma-associated protein, p130, PPAR-alpha-interacting complex protein 128, PRIC128, Retinoblastoma-related protein 2, RBR-2, pRb2.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPR1A_HUMAN
Sequence: MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED
What is the function of this protein?
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2.  May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
What are the official names of this protein?
Regulation of nuclear pre-mRNA domain-containing protein 1A, Cyclin-dependent kinase inhibitor 2B-related protein, p15INK4B-related protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0400 (RTT103) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_METFK
Sequence: MAKANVRVRKKVKKNIAEGIAHVHASFNNTIITITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAEAAGKAAQECGVKNLEVRIKGPGPGRESAVRALNAVGFKITSISDVTPVPHNGCRPPKKRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y1289_METM7
Sequence: MLKELINKLLWHPDYNPEDYNITYLHRGAKNDEKAVPLKNIVIEDSFLVFDETHVPFHRILEIVNLKTGEILYKKR
What are the official names of this protein?
UPF0248 protein MmarC7_1289.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: MELPH_MOUSE
Sequence: MGKRLDLSTLTDEEAEHVWAVVQRDFDLRRREEERLQGLKGKIQKESSKRELLSDTAHLNETHCARCLQPYRLLLNSRRQCLECSLFVCKSCSHAHPEEQGWLCDPCHLARVVKIGSLEWYYQHVRARFKRFGSAKVIRSLCGRLQGGGGSEPSLEEGNGDSEQTDEDGDLDTEARDQPLNSKKKKRLLSFRDVDFEEDSDHLVQPCSQTLGLSSVPESAHSLQSLSGEPYSEDTTSLEPEGLEETGARALGCRPSPEVQPCSPLPSGEDAHAELDSPAASCKSAFGTTAMPGTDDVRGKHLPSQYLADVDTSDEDSIQGPRAASQHSKRRARTVPETQILELNKRMSAVEHLLVHLENTVLPPSAQEPTVETHPSADTEEETLRRRLEELTSNISGSSTSSEDETKPDGTFLGGSPKVCTDTGHMETQERNPRSPGNPARPTKSTDEELSEMEDRVAMTASEVQQAESEISDIESRIAALRAAGLTVKPSGKPRRKSGIPIFLPRVTEKLDRIPKTPPADPDDQAKMPKATTAVPSLLRRKYSPSSQGVDSGSFDRKSVYRGSLTQRNPNGRRGTARHIFAKPVMAQQP
What is the function of this protein?
Rab effector protein involved in melanosome transport.  Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
What are the official names of this protein?
Melanophilin, Exophilin-3, Leaden protein, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a.
What are the subcellular locations of this protein?
Melanosome.
Protein: CRBB3_CHICK
Sequence: MTEQQSPPEQMVTGEGAGERGGNYKITIYELENFQGRRCELSEELPNVVDKALEKVGSIQVESGPWLGFERQAFAGEQFVLEKGDYPRWDSWSNSHNSDSLMSLRPLQIDSPDHKIHLFENAGYTGRKMEIVDDDVPSLWAHGFQDRVASVRALNGTWVGYEYPGYRGRQHVFEKGEYRHWNEWDANQPLMQSVRRVRDQQWHQRGSFENS
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin B3, Beta-B3 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: Y615_SYNY3
Sequence: MLTAFTAGLLLITVSELGDKTFFIAMILAMRYPRRWVLVGVVGGLAAMTILSVLMGQIFTFLPTRYINYAEVALFLIFGTKLLWDARRIKATANLEEMEDAEKAIASGEKKLKIVPRGWGIVVESFALTFVAEWGDRTQIATIALAASNNAWGVSAGAILGHTICAVIAVMGGKFVAGRISEKTVTLIGGLLFYLFAVVSWWTKIA
What are the official names of this protein?
GDT1-like protein sll0615.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHAP2_ESCF3
Sequence: MDATTIISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAVILLDGGMRTQASSFRVALGPALSLATVGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQHHETGVSWTFALDILQQFGLGILLGLGGGYLLQQMINRIALPAGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALLLSAWMIFFARPLSVFAGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLDNSRLFFNVAFFVVLISLLFQGTSLSWAAKKAKVVVPAVGWPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKDTRIAALFRDNVLLHPSGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEGSAKFADVAIIYGLDAGTEYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNQVMKVGVRVADEIAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3974_ARATH
Sequence: MASQTNKELFVGGLARILKEQRQVDVRLKAGDSDQKGVSISAHKLVLSARSEVFKMILETEEIKATTTLDTITLSELKHTELVALVE
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Putative BTB/POZ domain-containing protein At3g29740.
Protein: NADK2_BACSU
Sequence: MTDQRRNVYFFHKQDQETNEQARSLTQLAEEHGFTVVNQHSDANIIASIGGDGTFLQAVRKTNFRDDCLYVGITKKGKAHLYCDFHSDEREKMVDAMTFEQIEVRKYPLIEVTVDQASPFHCLNEVSIRSSIIKTFVMDVLIDDLHFETFRGDGMIISTPTGSTAYNKSVAGAVVDPLLPCMQVSELASLNNNTYRTLGSPFVLSSDRKLTLRVVQDGNEHPIIGLDNEALSTRNVKTIEIKLSNKKIKTVKLKDNSFWEKVKRTFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTA1_MYCTU
Sequence: MSPSMSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIPLVWLLWVVIARGWFAVTRSGWWTHSLRGVLPEQFAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYLVEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFAVALALVLLMLPVVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPIAMPGIVSGILLSIARVVGETAPVLVLVGYSHSINLDVFHGNMASLPLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRRRLPL
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstA 1.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATA_CAMJ8
Sequence: MITLKEALKYSKEELENLKKELNEKAKKEKKIGAYIEQFLDKDLSVSGEGVPVAIKDNISVKGWELTSASKILQGYIAPYDASVIVNLKANGFSPFGRCNMDEFAMGSSTASSYYGKTLNPLNFERVPGGSSGGSAAAVAGGLALASLGSDTGGSVRQPAAFCGCVGFKPSYGRVSRYGLASYSSSLDQIGVLTQNVEDAAILYDAIAGYDKMDSTSANIEFIKTAPNLNVNKKLKIAVIENYVNDADSEVKNALLKTIDMLKANGHEIVYKNLLDSKFDIAAYYIIATAEASANLSRYDGVRYGKRSENIQNLKEMYVNTRSEGFGEEVKRRILLGTFVLSSGYYDAYYIKAQKARAFIKAKYEEILQDCDLIFMPVTPTTAFKFDTQKSPMQTYLEDVYTISVNLAGLGGISVPVAKDKEELNISAQLICKAYDEQTLLDGALSLEQMIKH
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: FCYS_SCHPO
Sequence: MSSTELSEKDLAYLREAIKVSQQARDEGQHPFGCIIVDENDNVIMSAGNRVPDGDVTQHAETRAVGLITKTRRDLEKCTLYTSTEPCAMCSGAIFWSGIRRMIFGLSNENLIKLTQKSGECPPLYINSRDILGAASHPIEVVGPYIEDEAIIPHKGFWDGGR
What is the function of this protein?
Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine.  Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis.
What are the official names of this protein?
Probable cytosine deaminase, Cytosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACPS_SALA4
Sequence: MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_LOTJA
Sequence: MAVPKKRTSISKKLIRKNFWKKRGYWTALKAFSLAQSIFTGNSKSFFCNK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLSA_BACC1
Sequence: MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVANSELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMVTCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: IBP6_BOVIN
Sequence: MTPHRLLPPLLLTLLLAARPGGALARCPGCGQGVSAGCPGGCAEEEDGGPAAEGCAEAGGCLRREGQQCGVYTPNCAPGLQCQPPEKEDLPLRALLQGRGRCGRARTPSGENPKESKPQAGTARSQDVNRRDQQRNSGTSTTPSRSNSGGVQDTEMGPCRKHLDSVLQQLQTEVFRGAHTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVERMGQPLPGSSEGGDGSSLCPTGSSG
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.  Activates the MAPK signaling pathway and induces cell migration.
What are the official names of this protein?
Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6.
What are the subcellular locations of this protein?
Secreted.
Protein: MT797_ARATH
Sequence: MPTFPQSFPMNGGDGPHSYIHNSSYQKVAIDGVKERTSEAILEKLDLEFLNRNSEENILRIVDFGCSIGPNTFDVVQNIIDTVKQKRLKENKTYIGAPLEFQVCFNDQPNNDFNTLFRTQPFFSRKEYFSVGVPGSFHGRVLPKNSLHIGHTSYTLHWLSNVPQHVCDKKSPALNKSYIQCNNLVDEVTKAYKIQFRKDFGGFLEARAEELVSGGLMILSGQCLPDGIPKALTWQGVVIDMIGDCLMDLAKLGITSKEKIELFSLPTYIPHISEFKANIEQNENFNVETMEEISHPMDYMPLTNDFITSMFRAILNTIIEEHFGEGVVNELFSRLAKRLDKYPIDFKRCKKYVNYFIVLKRK
What are the official names of this protein?
Probable S-adenosylmethionine-dependent methyltransferase At5g37970.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: COBC_SINSX
Sequence: MSAPIVHGGGITEAAARYGGRPEDWLDLSTGINPCPVALPAVPERAWHRLPDRQTVDDARSAAADYYRTNGVLPLPVPGTQSVIQLLPRLAPANRHVAIFGPTYGEYARVLEAAGFAVDRVADADALTAEHGLVIVVNPNNPTGRALAPAELLAIAARQKASGGLLLVDEAFGDLEPQLSVAGHASGQGNLIVFRSFGKFFGLAGLRLGFVVATEPVLASFADWLGPWAVSGPALTISKALMQGDTKAIAAGILERRAGLDAALDGAGLNRIGGTGLFVLVEHPRAALLQERLCEAHILTRKFDYAPTWLRVGLAPDAAGDRRLADALARMEL
What is the function of this protein?
Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.
What are the official names of this protein?
Threonine-phosphate decarboxylase, L-threonine-O-3-phosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_CANAL
Sequence: MALQDVVTREYTINLHKRLHGVNFKKRAPKAVKEIKKFATLHMGTTDVRLDPKLNIAIWKRGVQGVENRMRLRISRKRNDEEDAKEKLFAYVEPVIVPSTKGLQTVVVEDDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L31-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: YHCR_BACSU
Sequence: MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNVTDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKITSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAMTLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGTTKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKNGYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAVENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKMKSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLYNIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVTLSGTYLYVRRKRSASRT
What is the function of this protein?
Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products.  No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values.
What are the official names of this protein?
Endonuclease YhcR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase SrtD.
Protein: NU2C2_CHLSC
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDSITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NEUT_RAT
Sequence: MIGMNLQLVCLTLLAFSSWSLCSDSEEDVRALEADLLTNMHASKVSKGSPPSWKMTLLNVCSLINNLNSAAEEAGEMRDDDLVAKRKLPLVLDDFSLEALLTVFQLQKICRSRAFQHWEIIQEDILDHGNEKTEKEEVIKRKIPYILKRQLYENKPRRPYILKRASYYY
What is the function of this protein?
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism.  It causes contraction of smooth muscle.
What are the official names of this protein?
Neurotensin/neuromedin N.
What is the protein family that this protein belongs to?
Belongs to the neurotensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Protein: CAURO_UROYA
Sequence: MKASTLVVIFIVIFITISSFSIHDVQASGVEKREQKDCLKKLKLCKENKDCCSKSCKRRGTNIEKRCR
What is the function of this protein?
This toxin only weakly stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (55% of the full conductance state obtained only at high concentrations (1 uM)) (PubMed:27114612).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 with the lowest activity of all calcins (EC(50)=376 nM) (PubMed:27114612).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:27114612).  It binds a different site as ryanodine (By similarity).  It acts synergistically with caffeine (By similarity).  In contrast to other calcins, it does not trigger calcium release from sarcoplasmic vesicles even at high concentration (1 uM) (PubMed:27114612).  In vivo, intracerebroventricular injection into mice induces neurotoxic symptoms, followed by death (By similarity).
What are the official names of this protein?
Urocalcin, UrCa, Calcium-channel toxin-like 20.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOF1_POLSJ
Sequence: MAINTPLTNSWLDEFPARIAELDRAHLRRRRRVVVPEDGAHLQVDGQRMLAFCSNDYLGLAGHPALVQAACDGARAFGVGAAASPLVSGHSAANEALEAALARFVGQPRALYFYAGYATNIGIVPALVGKGDAIFSDALNHACLIDGARLSSAQIHRYPHADLAALEQELISSPARRKLIISDAVFSMDGDVADVPALLALCERHDALLLLDDAHGFGVLGPQGRGCLAHFGLSGENASPRVLYMATLGKAAGVAGAFVAGSEALVEWLLQKTRSYIFATAAPALLATALQTSLQLIEQDEWRREHLQRLIARLRSGLAQGLQGSSWRLGESPTAIQPVVIGPNDAALAVMEGLRTRGLWVPAIRPPTVAEGTARLRIALSAAHTEADIDRLVQALTELAKPGSL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase 1, AONS 1, 7-keto-8-amino-pelargonic acid synthase 1, 7-KAP synthase 1, KAPA synthase 1, 8-amino-7-ketopelargonate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: GLPK_BORPE
Sequence: MTANEFILALDQGTTSSRAIVFDRAGTVRGMGQREFRQHYPRPGWVEHDAGEIWQSQLEVAREALRNAGASAADLAALGITNQRETTLIWERATGRPLARAIVWQDRRTAAMCEKLLHDGHGRMLQERTGLVVDAYFSGTKLAWLLDHVPGARKMAERGELAFGTMDTWLVWQLTGGAVHSTDPSNASRTMLFDLHAQDWSDDILALLNIPRGILPRIAPSSARIGETLPEWLGGSIPIAGVAGDQQAATFGQACFTPGMAKNTYGTGCFMLMNVGDAPVASRHNLLSTVGWSLPAGNATHATYMVEGGVFMAGAAVQWLRDGLGIIQRSADIEALAASVADTDDVFMVPAFAGLGAPHWDPYARGTLVGMTRGTTRAHIARATLESIALQSAELLSCMNADSGIPLSELRVDGSAARNDLLMQMQADLLGVPVVRPRVPESTALGAAGLAGLAVGFWSSLDEFGAQWQAERTFEPAWPADVREARMQRWRQAVELSKGWSRPAAGHA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: WZYE_PHOLL
Sequence: MTLTQFGGLFVVYLISLVFILTLTYQEFRRVRFNFNIFFSLLYLLTFYFGFPLTCLLVFQFDVEVVPVDALLHALLASTCFYGIYYVSYKTRLRKPSMQPKAPVFTMNRVETNFTWLLLASVAVVTVGLFFMQNGFLLFKLQSYSQIFSSQVSGVALKRFFYFFIPAMLVVYFLKPTQLRWLFFLISTVAFGILTYVVVGGTRANIIIAFALFLFIGIVRGWITLWMLVTAGAIGIVGMFWLALKRYSLDVSGAEAFYTFLYLTRDTFSPWENFALLLNNYDKIDFQGLAPIIRDFYVFIPSWLWPGRPDAVLNSANYFTWEVLDNHSGLAISPTLIGSLVVMGGVLFIPVGAIVVGLIIKWFDWIYELGKQETNRYKAAILQAFCFGAIFNMIVLAREGVDSFVSRVVFFCIIFGLCLVIAKLLYWLFESAGLIRMYLTGNRVVSQKCPLQCEERKWS
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.