PharMolix/UniProtQA huggingface dataset:
Protein: RL27_COXBU
Sequence: MAHKKAGGSTRNGRDSNPKMLGVKRFGGERVLAGNIIVRQRGTHYRPGENMGMGRDHTLYALIEGKVKFTRKGPKKRNFVSIEPLEESQP
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ASTD_LEGPH
Sequence: MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRALKSWANTSFEERARYTKAFVEQVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQAYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHLSNGHIVPALLAGNTVLYKPSEHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQFCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTGDLFLERFAKACKLMRIGSFDSQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLLLEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDEAIQLANQTRYGLSAGLLSDNKDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQPLLTTPVQRLPGLVLE
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: DNAJ_COXBN
Sequence: MAKRDYYEVLGVNRNATEAEVKKAFRRLAMKYHPDRNPGDKDAEVKFKEAREAYEVLCDSRKRASYDQFGHAGVEQTFGGAGAGGFGFGDLGDIFDDIFGDIFGGARGGQAREQRGADLAYELVLSLEEAVHGLSRTIKVPTWINCKTCNGSGAKKGSSPATCPRCNGSGQMRMQHGFLQVQQTCSVCRGRGQVIKDPCTDCHGQGRQQQTKTLSVKIPPGIDTGDRIRLAGEGEAGLFGAPPGDLYVQVRVKPHPLFHREGNDLHSEVPIDFTTAALGGEMEIPTLDGSVRLTIPPETQGGKQFRLRGKGVKALRSGAVGDLICHIVVETPVKLSPEQKDYLKQFAELLKKDEKNHSPRTRNWFDSVKDFFTSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET3_ASPTN
Sequence: MSSTAVVHDDDLMEPSLQSIVNQKTLRWIFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGFTNLSAMEIDPNGSIQDLLASGDAQQDDPMAGLGVNNMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSSQFGPMLNSILGARGGLPGGQNLDELLQKMESLRETISEVNSQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYSIDTHAIVVNQLLFPKDGSECDQCNARRKMQKKYLEQIEELYEDFNVVRMPLLVEEVRGKEKLEKFSDMLVHPYVPPN
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: Y1390_HAEIN
Sequence: MCLGVPIKLSKLMKILFNLPQ
What are the official names of this protein?
Uncharacterized protein HI_1390.
Protein: TSAB_VIBPA
Sequence: MSAKILAIDTATENCSVALLVNDQVISRSEVAPRDHTKKVLPMVDEVLKEAGLTLQDLDALAFGRGPGSFTGVRIGIGIAQGLAFGAELPMIGVSTLAAMAQASYRLHGATDVAVAIDARMSEVYWARYSRQENGEWIGVDEECVIPPARLAEEAQADSKTWTTAGTGWSAYQEELAGLPFNTADSEVLYPDSQDIVILAKQELEKGNTVPVEESSPVYLRDNVTWKKLPGRE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEBP1_XENLA
Sequence: MFGMIKNSLLGGVENNEGKLVSKGEKDGVAFEEREYEGGKFISTEVSGKPFDEASKEGVLRLLKYVGGSNNKSAGMGMTSPVIINSYPSENDTLQPNVKVLLRIPSQYQADPPVPTDNTIQIEDRESVTLYSTQFGGYAKEADYVSHAAKLRSCLGPDISYHSDYYMCCGYDPPMKPYGRRNEVWFIKNN
What is the function of this protein?
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound.  Binds with a high affinity to one molecule of heme or porphyrins.  It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities (By similarity).
What are the official names of this protein?
Heme-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the HEBP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT2_CALSI
Sequence: MPDPCCNDKCECKEGECKTGCKCKSCRCPPCDKCSSECKCTSKEECSKTCSKPCSCCP
What is the function of this protein?
Binds six divalent metal ions.  Known to bind copper and cadmium.
What are the official names of this protein?
Metallothionein-2B, MT-2B, Metallothionein-IIB, MT-IIB.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 3 family.
Protein: SELD_SHEB8
Sequence: MSDSPVTLPESIKLTEYSHGAGCGCKISPKVLSTILASQLPVFTDPNLLVGNQSRDDAAVYKLNDDIGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPIMAIAILGWPINKLPAEVAQQVVDGGRQACMEAGIMLAGGHSIDAPEPIFGLAVTGQIALTDLKQNDTAKAGDRLYLTKPIGIGILTTAQKQKKLQDEDSHIAVNAMCQLNTIGTTIAKISGVNALTDVTGFGLAGHLLEMCQGAKLTAKLKFDAVPLLPRALDYLALGCVPGGTHRNYDSYGEHLPELSEHQKAILCDPQTSGGLLVAVSAEAEAELIALLDAHHIAPICIGSLETPTTEANVVLY
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: BRL08_BRELC
Sequence: MAEFRFRPTTLLFLIVALIFRCAIDPVSANADLTPSPRLLRDLVQFDATQTVAHTLSNSPSASSSSAEATVHPAASAEASAISNHTTDNAASAESSAESKHELPSIMSFIGPAAAGVLAIVLIGAVIAFKYRSSK
What is the function of this protein?
Secreted effector that inhibits stress-induced relocalization of the transcription factor NAC069 to the nucleus, thus affecting its broad role in abiotic and biotic stress responses.
What are the official names of this protein?
Secreted RxLR effector protein BLR08.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host membrane; Single-pass type I membrane protein. Note=Localizes to unidentified ring-like structures of varying size within the host cell.
Protein: RPR1B_MOUSE
Sequence: MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAAEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKEVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD
What is the function of this protein?
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2.  Transcriptional regulator which enhances expression of CCND1.  Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site.  Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop.  Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A.  Promotes cell proliferation.
What are the official names of this protein?
Regulation of nuclear pre-mRNA domain-containing protein 1B, Cell cycle-related and expression-elevated protein in tumor.
What is the protein family that this protein belongs to?
Belongs to the UPF0400 (RTT103) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HXT8_YEAST
Sequence: MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Hexose transporter HXT8.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLGC_DECAR
Sequence: MPMSTSCPHQPYCEMREQTDMRFISHLTRNTFAIILAGGRGTRLKQLTDFRSKPAVPFAGKFRILDFTLSNCVNSGIRKIGVATQYKAHSLIRHIQRGWSFLDGRFDEFIQLLPAQQQIDETQWYQGTADAVYQNLHFLRRYQPDHILVVAGDHIYKMDYGRMLAHHVKHHADMTVACIDVPLDEAREFGVMGVDEQDRVIDFVEKPQNPPAIPGQPDRALASMGIYIFNTKFLFEQLERDAMTKGSNRDFGKDIIPYIVPRYRVFAHRFADSCVGSDNHRPYWRDVGTIDAYWEANMEMTKVTPELNVYDRDWPIWTYQEQIPPAKFVFDDEDRRGTAVDSLIAGGCIISGASVKRSLLFSSVNVHSWASVEDSVVLPDVDIGRHAVLKRCVIDKHCRIPEGMVIGVDPEEDRKRFHVSPKGITLVTAEMLGQGAAEGR
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: APBC_METJA
Sequence: MAECDGKCDTCPSKNTCPDTKKLLAQQDAKIRENMSKIKHKIVILSGKGGVGKSTVTVNLAAALNLMGKKVGVLDADIHGPNIPKMLGVENTQPMAGPAGIFPIVTKDGIKTMSIGYLLPDDKTPVIWRGPKVSGAIRQFLSDVVWGELDYLLIDTPPGTGDEQLTIMQSIPDIDGAIIVTTPEEVSVLDVKKSIMMAKMLNIPIIGIIENMSGFVCPYCNKVVDIFGRGGGEKAAKELGVEFLGRIPLDIKAREASDKGIPMVLLDCKASEEFKKIVKRIVEKVEGKKE
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: CT55_HUMAN
Sequence: MLRLLRLALAFYGRTADPAERQGPQQQGLPQGDTQLTTVQGVVTSFCGDYGMIDESIYFSSDVVTGNVPLKVGQKVNVVVEEDKPHYGLRAIKVDVVPRHLYGAGPSDSGTRVLIGCVTSINEDNIYISNSIYFSIAIVSEDFVPYKGDLLEVEYSTEPGISNIKATSVKPIRCIHTEEVCITSVHGRNGVIDYTIFFTLDSVKLPDGYVPQVDDIVNVVMVESIQFCFIWRAISITPVHKSSSGFQDDGGLGRPKRERRSQSI
What are the official names of this protein?
Cancer/testis antigen 55, Tumor antigen BJ-HCC-20.
Protein: PANB_SALEP
Sequence: MKPTTISLLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQACENAAIVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAGQVLLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDMRAAVQQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S11H_OPHHA
Sequence: MKPVLLTLVVVTIVCLDLGYTRICLKQEPFQPETTTTCPEGEDACYNLFWSDHSEIKIEMGCGCPKTEPYTNLYCCKIDSCNK
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Weak toxin DE-1 homolog 1, WTX DE-1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSE2_BOVIN
Sequence: MPGRSTSSSSSGSTGFISFSGVESALSSLKTFQSCISSGMDTASSVALDLVETQTEVSSEYSMDKAMVEFAMMDRELNHYLKAVQSTINHVKEERSEKIPDLKLLVEKKFLALQNKNSDADFQNNEKFVQFKQQLKELKKQYGLQSDREADITEGVDEDMIVTQSQTNFICPITQLEMKKPVKNKVCGHTYEEEAIVRMIESKHERKKKACCPKIGCSHVDMRMSDLIQDEALRRAIESHKKRRRQSN
What is the function of this protein?
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination.  Is not be required for the stability of the complex.  The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.  Acts as an E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TSNAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, RAD51AP1, and maybe the cohesin components RAD21 and STAG2.  Required for recruitment of telomeres to PML nuclear bodies.  Required for sister chromatid cohesion during prometaphase and mitotic progression.
What are the official names of this protein?
E3 SUMO-protein ligase NSE2, E3 SUMO-protein transferase NSE2, Non-structural maintenance of chromosomes element 2 homolog, Non-SMC element 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSE2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Nucleus, PML body. Note=Localizes to PML nuclear bodies in ALT cell lines.
Protein: US23_HCMVA
Sequence: MWRTRWEDGAPTFTRNDEFLYCHTRYETFLRVMGDFQGIFECQYSADVLRDWVRNHVDQVLSLGIPHNWFLQVRPGSTMPELRDQLLDDVICCPERLIVLGKCVIMVEDHYEETELVLCMGGGTRLYIYEPSQEILLLCARHLDELARYGMMYTEAVYRQPQTPFATRVPHDVVAMLLRHGHDADALAACVGEHHGRDVNFHTPGRHAKTLKLLTSFGCLTDCWPFEVAPAARLAECEMYVTLQLRCRWYLLGAVGSYRAGGFFDTSFLIIFDRFCRFYVVIVKSHLDRSPPLQRLAGEIYRLADSLEELFRAGLMKVYVRRRYEHGLRRAARLERNGGCVHMGEAARLHFTMFDSGVDRDYARQFRWLCRGDRFRAEMLNNWDGWDAFTIWQARVVRGDFAERRRPRSLGDGEEEDEGNDGRAMPVVRRRPPPMPRDDDEDNHVVPDNQNLEVIHDALADDEEQGEDDDDSGAEPMEPEENNVVPNVERRGGEDAVAARMAAGHESDDDEWEDLGFDLEEDTVFDLKDVDEWFEQRRLAEKERWHLGQRIVNAYRTEAEVSEAEVEARRINLNTDLSPEWVKSFDFREHFV
What are the official names of this protein?
Tegument protein US23, Protein HHLF7.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: NTPPA_ROSDO
Sequence: MFILGSGSPRRKELLAQIGVVPDDIRPPDINETPLKGELPRPYCARMAREKACAVDALPDDVVLCADTTVALGRRILGKPEDATEAAAFLKLLSGRRHRVITAIAVRVAERVWEKDVVSIVRMKSLSQAEIQSYIDSEDWRGKAGGYGIQGPAAALIPWISGSYTGIVGLPLAETAGLLQAAGYRGAS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGN_SHIF8
Sequence: MAEHLMSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDLPAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: STS1_ZYGRC
Sequence: MENNTAVLGAGFSWGFKSDNVMKCQEQEEQQARENEKSLNSMVANLVQAQGMDPKGRKRRLDEPTNPQPQMMVPPRKYNVSKRRPHHSTISGQPLPLHRGLELMSKDQLQYILIEVMKNYPISQQLVQNKLVDFNFSIEKCEILLKEKLQQLHESIPYSRSHDYQRLSDYAFVRMKPHILEFLNCLVDCVLDRIPPRVDNLHESLKILDMTTDMVTKLPRFQLASNNYYYDKCLEQLACLWCTVIEHIARDVIMTVNDAPLLRNWIQKLELYNELCHGILTKPLNQFKSLAVVDAGVTDSNSTKGTNATRNRWSGSTDNYTVGDNQ
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLGB_PROM2
Sequence: MIETIQADWIKSEAINLENCCNDNPLKILGPHFYEEQWVIRVWMPEADEVKINFKNNTYKAESINHKWLFEAILPENPNFNYEINISRGGITHTQHDPWSYREEWMGEVDRHLFAEGNHHHIWEKMGAHLIEEKNQKGVMFCIWAPNAKSISIIGDINSWDGRHHPMQKRLGGIWELFMPTMKEGDTYKYEIRTQQGHIYEKADPYGFLHEIRPQNGSIVSKLKNFNWNDSSWISNRDSSSQINKPISVYEMHLGSWLHESTDNKYLEDNGEPRDPVPAADLKPGTRLLTYPELTEKLIPYVKDRGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRFGTPNEFREFVNKCHEEGIGVILDWVPGHFPKDKHGLAFFDGCHLYEHGDSRIGEHKEWGTLIFNYSRNEVRNFLVANLIYWFEEFHIDGIRVDAVASMLYRDYLRPDGEWIPNENGGNENIEAVKFLQQANHVLFQHFPGALSIAEESTTWPMVTKPTDMGGLGFNLKWNMGWMHDMLDYFEIDPWFRQFHQNSVTFSITYNYTENFMLALSHDEVVHGKSHLLHKMPGDDWKKYANTRALLTYMWTHPGKKTIFMGMEFGQRQEWNVWDDLQWELLEFEPHKGIRNLIDDLNALYKNEAALWKNDFDPYGFQWIDCNDKSNSVISFMRRENDTNEWLVVVANFTPNTHGSYKVGVPVEGFYKEIFNSDGSRYGGSNKGNMGGKETINYNIHDYQNALELALPPLSVSIFKHLSKK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: DNAA_NITEC
Sequence: MQKIETFWYFCLKHFKQELNGQQFNTWIKPLKLEICPDVENTLVLIAPNRFVLQWIKDNFVNRIDEMAQGHFNEKIHFKLELKDPAEIKTATIKAPEPKSKEDKKPPTDKAHGTTARKTNPSRLNPAFTFDAFVTGKANQLARAGAIQVAERPGIAYNPLFIYGGVGLGKTHLMHAVGNYVMELDAGAKIRYVHAEKYVSDVVSAYQHKSFDKFKLYYHSLDLLLVDDVQFFSGKNRTQEEFFYAFNALIEAHKQVIITSDCYPKEISGLEERLVSRFGWGLTVAIEPPELEMRVAILLKKAFIEKIELDESTAFFIAKYIRSNVRELEGALKRVLAYSRFTGHPISLDLAKEALKDLLAIQNRQISIENIQKTVADYYKIKVADMYSKKRVRAIARPRQVAMAIAKELTQLSLPDIGEAFGGRDHTTVLHAHRKIVELRASDPGINRDYSTLIHILRG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O6C74_HUMAN
Sequence: MRNHTTVANFILLGLTDDPQLQVIIFLLLFFTYMLSITGNLTIITLTLLDLHLKTPMYFFLRNFSFLEVSFTTVYIPKFLVSMATGDKTISYNDCAAQLFFTILLGATEFFLLAAMSYERYVAICKPLHYTTIMSSRVCSLLVFASWMAGFLIIFPPLLMGLQLDFCAANTVDHFFCDVSPILQLSCTDTDIIELMMLLSAILTLLVTLVLVILSYTNIIRTILKIPSSQQRKKAFSTCSSHMVVVSISYGSCIFMYVKPSAKERVSLNKGIALLSTSVAPMLNPFIYTLRNKQVKDVFKHTVKKIELFSMK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6C74.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSP_PARPJ
Sequence: MKLEHPDRLMNRTPLSLAALEVHDAFAERHIGPDAADQHAMLEALGFASRAALIDAVIPKTIRRTETLPLGPFTQPKSEAEALAALRELADKNQVFRSYIGQGYYNAHTPTVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMIVDLTGLAISNASLLDEATAAAEAMTLLQRVGKPKSNVFFVADDVLPQTIEVVRTRATPVGIEVKVGPASEAANANAFGVLLQYPGVNGDVRDYRALTEAIHAAGGHVVVAADLLALTVLTPPGEWGADVAVGNTQRFGVPVGFGGPHAAYLAVRDEFKRQMPGRLVGVTVDAQGNPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPHGLKTIALRVNRIAALLAEGAKQLGYTLANETFFDTLTFDTGARTQALLDAATAKRINLRRVSATQVGLSIDETTTRHDLADLLAVFAQAAFTNDVPQVDALDAKLAASNTASVPAALERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGQIHPFAPAEQTVGYREMIDQLEEMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGEAHRNVCLIPASAHGTNPASAQMAGMQVVVVACDAQGNVDIEDLKKKAGQHADKLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGAHLAQFLPNQISSGYERAPNGIGAVSGAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYVAKKLAPHYPVLYSGPGGLVAHECILDLRPIKETSGITVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESKEELDRFIEAMIAIREEIRAVEDGRSDREDNPLKHAPHTAAVVIANDWKHAYARETAAYPLPTLIAKKYWPPVGRADNVYGDRNLFCSCVPIADYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RLMH_SALSV
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O1616_CONVE
Sequence: MMKLTCVLIIAVLFLTACQLTTAETRDEYRAVRSSDEVRNSRSCSGSGYGCKNTPCCAGLTCRGPRQGPICL
What are the official names of this protein?
Conotoxin VnMKLT2-011.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.