PharMolix/UniProtQA huggingface dataset:
Protein: DRN1_YEAST
Sequence: MTNAKILVAHISESDADEAIRKIKKVNEKSGPFDLIIIFSNSYDENFELNTDGLPQLILLSCDKANNSKSKKINENVTLLHNMGTYKLANGITLSYFIYPDDTLQGEKKSILDEFGKSEDQVDILLTKEWGLSISERCGRLSGSEVVDELAKKLQARYHFAFSDEINFYELEPFQWERERLSRFLNIPKYGSGKKWAYAFNMPIGDNELKDEPEPPNLIANPYNSVVTNSNKRPLETETENSFDGDKQVLANREKNENKKIRTILPSSCHFCFSNPNLEDHMIISIGKLVYLTTAKGPLSVPKGDMDISGHCLIIPIEHIPKLDPSKNAELTQSILAYEASLVKMNYIKFDMCTIVFEIQSERSIHFHKQVIPVPKYLVLKFCSALDRQVHFNNEKFTRNAKLEFQCYDSHSSKQYVDVINNQSNNYLQFTVYETPEADPKIYLATFNASETIDLQFGRRVLAFLLNLPRRVKWNSSTCLQTKQQETIEAEKFQKAYRTYDISLTEN
What is the function of this protein?
Involved in branched RNA metabolism, modulating the turnover of lariat-intron pre-mRNAs by the lariat-debranching enzyme DBR1.  Enhances the debranching activity of DBR1 in vitro.
What are the official names of this protein?
CWF19-like protein DRN1, Debranching enzyme-associated ribonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the CWF19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Relocalizes to the cytoplasm in response to hypoxia.
Protein: ACTMP_DANRE
Sequence: MSLENDAAAPPPPPLPPPPPPQPPSLARSESSKKKLYQALAEGRTAVEGDYEEASIIIGQRESSFSKDLQWLLFNNYVPSLIQDGPQCGLVALWMAAHLLQPPKTLLLETLVQTAKDNGYTEQGEMFSASDMAKLAEDVCGCRVQRLSGGMLGENTAVILKHLINRQPILIPYDEDFNHEPCLRNGHKAHWAVASGILLGLREGCVNYKHFPPDITLPWLRLAQSEASVSWPIDDIEEVFVLAKQGKSLRYQLWEFESVAQSNKQLKEMDPQRASDGTRYVLPPGGVQDGLAGQVLLLHTNTEQTKN
What is the function of this protein?
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation (By similarity).  Cleaves N-terminal acetylated methionine of immature cytoplasmic actin after translation (By similarity).  Cleaves N-terminal acetylated cysteine of muscle actin after canonical removal of N-terminal methionine (By similarity).
What are the official names of this protein?
Actin maturation protease, Actin aminopeptidase ACTMAP.
What is the protein family that this protein belongs to?
Belongs to the ACTMAP family.
Protein: PO4F2_MOUSE
Sequence: MMMMSLNSKQAFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAGGGGGGGGGGGGGGRSSSSSSSGSGGSGGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGTVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAGI
What is the function of this protein?
Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells (PubMed:7904822, PubMed:8995448, PubMed:8972215, PubMed:10357904, PubMed:10414983, PubMed:11163266, PubMed:17668438, PubMed:25775587).  Functions either as activator or repressor by modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner (PubMed:7904822, PubMed:7935408, PubMed:8065921, PubMed:7852360, PubMed:7797498, PubMed:8662774, PubMed:9694219, PubMed:10526314, PubMed:15733064, PubMed:17145718, PubMed:18368538).  Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes (PubMed:7904822, PubMed:8290353, PubMed:9111308, PubMed:10414983, PubMed:16152597, PubMed:17668438, PubMed:24643061).  Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation (PubMed:8632990, PubMed:10357904, PubMed:25775587).  Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding (PubMed:8995448, PubMed:9261145, PubMed:8972215, PubMed:10357904, PubMed:11163266, PubMed:24643061, PubMed:25775587).  Inhibits DLX1 and DLX2 transcriptional activities preventing DLX1- and DLX2-mediated ability to promote amacrine cell fate specification (PubMed:21875655).  In cooperation with TP53 potentiates transcriptional activation of BAX promoter activity increasing neuronal cell apoptosis (PubMed:17145718).  Negatively regulates BAX promoter activity in the absence of TP53 (PubMed:17145718).  Acts as a transcriptional coactivator via its interaction with the transcription factor ESR1 by enhancing its effect on estrogen response element (ERE)-containing promoter (PubMed:9448000).  Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to an octamer motif (PubMed:7935408, PubMed:8065921, PubMed:8537352, PubMed:7852360, PubMed:8662774).  Involved in TNFSF11-mediated terminal osteoclast differentiation (PubMed:17668438).
What are the official names of this protein?
POU domain, class 4, transcription factor 2, Brain-specific homeobox/POU domain protein 3B, Brain-3B, Brn-3B, Brn-3.2.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.
Protein: UBIA_PARP8
Sequence: MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPSVSLLVIFALGTILMRSAGCAINDYADRDFDRYVKRTENRPITSGKIKAWEAVALAAGLSLVAFLLILPLNALTKELSVAALFVAGTYPFTKRFFAIPQAYLGIAFGFGIPMAFAAVQNQVPLLAWVMLIANVFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVLAIMLCYAVTLGIYVGIGFTLGFGVLYWIGLAAAAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGALFAGIAAHYAAQAF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF3_METS4
Sequence: MPAPQKDGPRANRDIRGVREVQLIDETGQNRGVMGFFDALQVAEEAGLDLVEIAPNSTPPVCKLLDYGRYRFNEQKKQAEARKRQKTVEVKEIKLRPGIDKHDYDVKMKAVQRFFEEGDKVKVTLRFRGREMAHQDLGLRLLERVKAETQEIAKVESEPQLEGRQMIMILAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_SHISS
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZRAB3_HUMAN
Sequence: MPRVHNIKKSLTPHISCVTNESDNLLDFLPDRLRAKLLPFQKDGIIFALKRNGRCMVADEMGLGKTIQAIGITYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVRRMSTSKVTVLGYGLLTADAKTLIDALNNQNFKVVIVDESHYMKSRNATRSRILLPIVQKARRAILLTGTPALGRPEELFMQIEALFPQKFGRWTDYAKRYCNAHIRYFGKRPQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKVRQRIPFDLPSAAAKELNTSFEEWEKIMRTPNSGAMETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVSSSERIHLVNQFQKDPDTRVAILSIQAAGQGLTFTAASHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWGMLNRKAQVTGSTLNGRKEKIQAEEGDKEKWDFLQFAEAWTPNDSSEELRKEALFTHFEKEKQHDIRSFFVPQPKKRQLMTSCDESKRFREENTVVSSDPTKTAARDIIDYESDVEPETKRLKLAASEDHCSPSEETPSQSKQIRTPLVESVQEAKAQLTTPAFPVEGWQCSLCTYINNSELPYCEMCETPQGSAVMQIDSLNHIQDKNEKDDSQKDTSKKVQTISDCEKQALAQSEPGQLADSKEETPKIEKEDGLTSQPGNEQWKSSDTLPVYDTLMFCASRNTDRIHIYTKDGKQMSCNFIPLDIKLDLWEDLPASFQLKQYRSLILRFVREWSSLTAMKQRIIRKSGQLFCSPILALEEITKQQTKQNCTKRYITKEDVAVASMDKVKNVGGHVRLITKESRPRDPFTKKLLEDGACVPFLNPYTVQADLTVKPSTSKGYLQAVDNEGNPLCLRCQQPTCQTKQACKANSWDSRFCSLKCQEEFWIRSNNSYLRAKVFETEHGVCQLCNVNAQELFLRLRDAPKSQRKNLLYATWTSKLPLEQLNEMIRNPGEGHFWQVDHIKPVYGGGGQCSLDNLQTLCTVCHKERTARQAKERSQVRRQSLASKHGSDITRFLVKK
What is the function of this protein?
DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events (PubMed:21078962, PubMed:22704558, PubMed:22705370, PubMed:22759634, PubMed:26884333).  Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase (PubMed:22759634).  In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks (PubMed:22705370, PubMed:22704558).
What are the official names of this protein?
DNA annealing helicase and endonuclease ZRANB3, Annealing helicase 2, AH2, Zinc finger Ran-binding domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Following DNA damage, recruited to sites of DNA damage and stalled replication forks by polyubiquitinated PCNA (PubMed:22704558, PubMed:22705370, PubMed:22759634).
Protein: GTR2_MOUSE
Sequence: MSEDKITGTLAFTVFTAVLSSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRKAAINYDVNGTDTPLTVTPAYTTPAPWDEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYIKLEEEVRAKKSLKRLRGTEDVTKDINEMKKEKEEASTEQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDKFAWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCFQYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEFRKKSGSAPPRKAAVQMEFLASSESV
What is the function of this protein?
Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose.  Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell.  May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.  Also able to mediate the transport of dehydroascorbate.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_LEGPL
Sequence: MKVRASVKRICRNCKIIKRSGTIRVICKDARHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ATPG_MYCSK
Sequence: MAATLRELRGRIRSAGSIKKITKAQEMIATSRIAKAQARVEAARPYDREITNMLTELATASALDHPLLVQRENPRRAGVLVVSSDRGLAGAYNANVFRRSEELFSLLREEGKEPVLYVVGRKALSYYSFRNWDVTESWSGFSERPEYEHAQEIGETLVKAFMAGVDDEGDDAGADGILGLDELHIVFTEFRSMLSQSAIARRIAPMVVEYSEEDTNEPHTLFSFEPSAETLFDALLPRYVSTRIFAAMLEAAASESASRRRAMKSASDNADDLIKDLTLMANRERQSQITQEISEIVGGANALADAAKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEU1_PSESM
Sequence: MTMLNDPSKKYRAFPTIDLPDRTWPSKTIDAAPIWCSSDLRDGNQSLIEPMDSVKKLRFWKTLVSVGVKEIEASFPAASQTDFDFVRTLIEDGHIPDDTTIQVLTQAREDLIARTFESLRGAKKAIVHLYNATCPSFRRIVFNQDKAGVKEIAVNAAKLFVKYAAQQPETQWTFEYSPETFSATELEFAKEVCDAVIEVWNPTPENKVILNLPATVEVATPNIYADQIEWFGRHITRRDSVLISLHTHNDRGTGVAATELGLMAGADRVEGCLFGNGERTGNVDLVTVALNLYTQGINPELDFSDIDGVRKVVEECNQIPVHPRHPYVGDLVHTAFSGSHQDAIRKGFTQQKEGELWEVPYLPIDPADIGRSYEAVIRVNSQSGKGGIAYLLEQEYGISLPRRMQIEFSQVVQGETDRLGLEMTAEQIHALLRREYLQANTPYALISHRLQEENGNSAVDAEVHVDGETQHWRGKGKGALEALVAGLPVAVEIMDYNEHAIGSGTTAKAAAYIELRVNGDRAVHGVGIDENITTASFRALFSALNRSLSQAQAKAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: ALLTR_BANDI
Sequence: GFKNVALSTARGF
What are the official names of this protein?
Allatotropin-related peptide, ATRP.
What are the subcellular locations of this protein?
Secreted.
Protein: PGSA_WIGBR
Sequence: MRLNIPTCLTLFRLIIVPFFIIVFYLPFSNASFYSAIIFILAALTDWFDGFLARKLNQTTCFGAFLDPVADKIIVVIGLILIIEYFHSFWITIPSLIMIIREIIISSLREWMAEIGKNNLLSVSLISKLKTSIQMLAIFSLLWKETYIIIIIGILSLYVSSILAFLSMLKYFYIAWRDLFRN
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_COXBR
Sequence: MPYIGSLKVNQFRNLADVDITPHSQFNFFFGQNGAGKTSILESIYYLSVGRSFRTHLPQRLIQDNTDRFLIFITLYNGTQFIPLGVERDCHGDRCLRINGETASSWSLAAKRLPLCSLSAMSHRFLLDGPRVRRQFLDWLMFHVEPSFFSIWQRLQRSLKQRNAALKAKLPLGEITHWDKMLVEDGERLHQLRQNVVTEFKPLFTQMLQQFLPAYPLIGHYFRGWSEKYSLMEQLQINLKQDLQRGYTQAGPQRADFRLTLGDLPAQDILSQGQQKLVTYALHFAQGLLLKEKTGISPIYLIDDLPAELDANKRDCVIDLVNCLESQVFISGIDPNEIRLPPHSTLFHVKHGKVAAL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ALIB4
Sequence: MNNKTIGIIGVGNVGSTLAFILATNNICSNILLKDIKNNISEAMALDISQAMQETNSNTKITACLNNEDFKDCDIIIITAGIARKPNMSRDDLLITNAKIVASVMNDISKNNPNAIIIIISNPLDSMVYTALKSSNYPKNKILGMAGTLDSARMSYFIAEKLGFPNVNIKTSVIGGHGDSMVPLIDFSTVDGKKLNEVLSKEDIDDIVIKTKNGGGQIVKLLETGSAYYAPAYSTIAMIEAILNDTKKCFACATILNGEYGYKDIVSGVPVILGKDGVEKIIELEISDFEKEQFSNSINSVKESINILENNFFN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: RADB_THEKO
Sequence: MLSTGTKSLDSLLGGGFAPGVLTQVYGPYASGKTTLALQTGLLSGKKVAYVDTEGGFSPERLVQMAETRGLNPEEALSRFILFTPSDFKEQRRVIGSLKKTVDSNFALVVVDSITAHYRAEENRSGLIAELSRQLQVLLWIARKHNIPVIVINQVHFDSRTEMTKPVAEQTLGYRCKDILRLDKLPKPGLRVAVLERHRFRPEGLMAYFRITERGIEDVE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: PVK1_ENTSB
Sequence: QGLIAFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, Entsp-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_SPHAL
Sequence: MAKLTKKQKALEGKVDAQKLHGVDEAIKLVRELATAKFDETLEIAMNLGVDPRHADQMVRGVVTLPAGTGKDVKVAVFARGDNAEKALAAGADKVGAEDLMEDMLAGNLDYGRVIATPDMMGIVGRLGKTLGPKGLMPNPKLGTVTPNVAEAVKAAKGGQIEFRVEKVGIIHAGLGKLSFGEEKLRQNFDAFVDAIVKAKPAGAKGKYVRKVALSSSMGPGVKVDTAELTGA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RPOA_MANSM
Sequence: MQGSVTEFLKPHLVDIEQVSPTHAKVILEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEVLLNLKGLAVKVQNKDDVFLTLNKSGIGPVVAADITHDGDVEIVNPEHVICHLTDENASINMRIRVQRGRGYVPASARVHAQDEERPIGRLLVDACYSPVDRIAYNVEAARVEQRTDLDKLVIELETNGAIDPEEAIRRAATILAEQLDAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAETIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LIPB_FRATN
Sequence: MNNIYQKDLGLQQYNKVFENMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_MICAN
Sequence: MINYLRGQAIEVIKTPNNRLILILDVNQIGYEIQIPSRLALDIGNNNNDSCQIFTHLLLREEQPLLYGFGTAPERELFRQLLSVNGVGAQLALALIDTLGIEELVVAIVTGNTKILSKTPGVGLKTAERIALELKTKLAAWRQLREATTTITAILPAAAILEDVQMTLLALGYSQEEIDRAMAVLSQDALFSKNTQPEDWIKGAINWLG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NCPP_ECO27
Sequence: MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENTSQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRTSVYHQAVILALSPFHNAVYQPLQA
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: HEM1_SACD2
Sequence: MTLIALGINHNTASLDVREKVAFSSTQIESALRAAIAGAGLSEVAILSTCNRTELYAYGSSQANSLIQWLAEYKQVNVAELEQSHYLYTASEAASHMMKVASGLDSLVLGEPQILGQMKSAYAVAREAGVLGGHLHDVFQRVFSVAKRVRSETAIGENPVSVAYAAVSLAQQIFSDLKQDTALLIGAGETIELVARHLAEQGIKKLIVANRTLGNARSLAEQFGAEAILLADIPEHLHRADIVISSTASQLPLLGKGAVEQALKRRRHKPMFMVDIAVPRDIEAQVGDLADVYLYTVDDLKEVIDENMRSRQQAAKIAEEIIVEGLLHYEREQRALTSVDTIKALRQTMDALREQELEKSRKALEAGADPAQVLEQLARSLTNKFLHTPSTQLKQAGADGEQDMLRTVRTLFSLPSANESKSEKE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NAMA_BACSU
Sequence: MARKLFTPITIKDMTLKNRIVMSPMCMYSSHEKDGKLTPFHMAHYISRAIGQVGLIIVEASAVNPQGRITDQDLGIWSDEHIEGFAKLTEQVKEQGSKIGIQLAHAGRKAELEGDIFAPSAIAFDEQSATPVEMSAEKVKETVQEFKQAAARAKEAGFDVIEIHAAHGYLIHEFLSPLSNHRTDEYGGSPENRYRFLREIIDEVKQVWDGPLFVRVSASDYTDKGLDIADHIGFAKWMKEQGVDLIDCSSGALVHADINVFPGYQVSFAEKIREQADMATGAVGMITDGSMAEEILQNGRADLIFIGRELLRDPFFARTAAKQLNTEIPAPVQYERGW
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase, Xenobiotic reductase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.