PharMolix/UniProtQA huggingface dataset:
Protein: PG070_VAR67
Sequence: MAAVVPRFDDVYKNAQRRILDQETFFSRGLGRPLMKNTYLFDNYAYGWIPETAIWSSRYANLDASDYYPISLGLLKKFKFLMSLYKGPIPVYEEKVNTEFIANGSFSGRYVSYLRKFSALPTNEFISFLLLTSIPIYNILFWFKNTQFDITKHTLFRYVYTDNAKHLALARYMHQTGDYKPLFSRLKENYIFTGPVPIGIKDIDHPNLSRARSPSDYETLANISTILYFTKYDPVLMFLLFYVPGYSITTKITPAVEYLMDKLKLTKNDVQLL
What is the function of this protein?
May play a role in the biogenesis of the viral factories by recruiting and wrapping DNA replication sites in endoplasmic reticulum derived membranes.  Later in infection, phosphorylation by the late viral kinase OPG054 might decrease DNA-binding ability and trigger ER membranes disassembly.  Binds DNA in vitro.
What are the official names of this protein?
Protein OPG070, Protein E8.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG070 family.
Protein: CTX16_LACTA
Sequence: MKYFVVALALVAAFACIAESKPAESEHELAEVEEENELADLEDAVWLEHLADLSDLEEARGFFGNTWKKIKGKADKIMLKKAVKIMVKKEGIFKEEAQAKVDAMSKKQIRLYLLKYYGKKALQKASEKL
What is the function of this protein?
Insecticidal, cytolytic and antimicrobial peptide.  Forms voltage-dependent, ion-permeable channels in membranes.  At high concentration causes cell membrane lysis (By similarity).
What are the official names of this protein?
M-zodatoxin-Lt8i, M-ZDTX-Lt8i, Cytoinsectotoxin 1-6.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 06 (cytoinsectotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_HYDCU
Sequence: MQEKLQAIVAQAKETIHSVSELVHLDEIRVQYLGKKGELTAMMKTLGQLSAEERPKAGQIINEAKQSVQTFLSEKKAELEDAILAAKLAGETIDVSLPGRGLDTGGLHPVTRTLRRIETIFSKAGFDVATGPEIEDDWHNFEALNIPETHPARAMHDTFYFDENTVLRTHTSGVQIRTMEEKDAPMRIIAPGRVYRCDSDQTHTPMFHQVEGLIIEENTSFAQLRTLIIEFLRQFFEDENLKVRFRPSYFPFTEPSAEVDIATNLFGDGRWIEVLGCGMVHPNVLKNVDVDSEKYTGLAFGLGVERLAMLRYGVTDLRQFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEBG_ECOL6
Sequence: MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTNSPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA
What are the official names of this protein?
Uncharacterized protein YebG.
Protein: TMCA_SHIF8
Sequence: MAELTALYTLTAQMKREGICRLLVLSGEEGWCFDHALKLRDALPGDWLWISPQLDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWLVLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNDAILWRQNQPFSLAHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAGSAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLVSRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEALVFNDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTLPLDLRRMMDAPGQHFLQAAGENEIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLAATLRGRRVSRIAVHPARQREGTGRQLIAGALQYTHDLDYLSVSFGYTGELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGEMLPVDPLNDAILSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQLCTTLKLSGRKMLLVRQREEAAQALFALNEVRTERLRDRITQWQFFH
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_RUTMC
Sequence: MVKKGSSGRWMSEHINDEFVKKAQKSGYRSRSVYKLIEVINKDKFIKLGDKVLDLGAAPGGWSQVAIKIVGKSGQVIASDILDIKPIDGVDFLRGDFTKDSVYETLLDITMSKKVDVVLSDMAPNMSGQSSIDIPKSMYLCELALDMAIKTLTPLGYFFVKVFQGNGFNEFVKLCRSSFSFVTIRKPKASKLRSKEVYLLTSKLKLT
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_RHOE4
Sequence: MLRTHLAGSLRPEQAEQTVTLTGWVARRRDHGGVIFIDLRDASGVAQVVFRAGDVAEQAHRLRAEYCVRVTGTVEVRPEGNQNFEIPTGAIEVNATELEVLNESAPLPFQLDDQVGEEARLKYRYLDLRREGPGSAIRLRSKVSAAARGVLAHHEFVEVETPTLTRSTPEGARDFLVPSRLQPGSFYALPQSPQLFKQLLMVGGIERYYQIARCYRDEDFRADRQPEFTQLDIEMAFVNQDDIILLAEEILTALWKLVGHEIKTPIDRMTYTEAMRRYGSDKPDLRFDIELVECMDFFKDTTFRVFQAEYVGAVVMPGGASQPRKQLDAWQEWAKQRGAKGLAYVLVGEDGTLGGPVAKNLTDAEREGLAAHVGAQPGDCVFFAAGATKPMRALLGAARGEIARKKDLIDPDAWAFVWIVDAPMFEPTADATASGDVALGHSAWTAVHHAFTSPKPEFFDTFDTDPDSALAYAYDIVCNGNEIGGGSIRIHRKDIQERVFKVMGISEEEAQEQFGFLLDAFAFGAPPHGGIAFGWDRITALLAGMDSIREVIAFPKSGGGVDPLTDAPAPISAQQRKESGIDAKPEKKSEDKKSEGDTAEAK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBHS_ECO57
Sequence: MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQTFEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD
What is the function of this protein?
Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone.  Probably involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable multidrug ABC transporter permease YbhS.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RTNLE_ARATH
Sequence: MAEEIEKSVPTEESLMEKISEKIHHHDSSSSSESEYEKPDSPSAVKAKIYRMFGREKPVHKVLGGGKPADVFLWRDKKLSGAVLGVATAIWVLFELVEYHLLSLLCHISILALGGLFLWSNAHTLINKTSPQIPEIHVPEEAFLVVASSLRNELNQAFVILRSIALGRDLKKFLMVVVGLWIISVVGNWFNFLTLVYICFVILHTVPMLYEKHEDKVDPLAEKAMKELQKQYVVFDEKVLSKIPIASLKAKAKLG
What are the official names of this protein?
Reticulon-like protein B5, AtRTNLB5.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EFTS_ECO5E
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_AZOSB
Sequence: MNNESKCPFAAAHGVRSPATARANRDWWPNQLNLNILHQHAPASNPLGEDFDYAAEFNTLDLAALKQDLYALMTMSQDWWPADWGHYGGLFIRMAWHSAGTYRTADGRGGGGTGNQRFAPLNSWPDNGNLDKARRLLWPIKQKYGNKISWADLMILAGNCALESMGFKTFGFGGGRADIWQPEEDIYWGAEKEWLATSDKPDSRYSGERQLENPLAAVQMGLIYVNPEGPDGNPDPVASGRDVRETFARMAMNDEETVALVAGGHTFGKAHGAGDPKLVGPEPEGAPIEAQGLGWINSFGTGHGVHTTTSGIEGAWKPNPTKWDNGYFDMLFGYEWALTRSPAGAHQWVAQNVKPEDMIPDAHDPSKKHPPMMTTADLSLRFDPIYEPIARRFHKNPADFADAFARAWFKLTHRDMGPKSRYLGPEVPAEDLIWQDPIPRLDHPLIDAADIATLKAMVLASGVSIAELVSTAWASASTFRGSDMRGGANGARIRLAPQKDWDVNQPAQLAKVLSVLGDIQAGFNAAAPGGKKVSLADLIVLGGCAAVEAAARAAGHVVEVPFTPGRMDASQEQTDVESFAVLEPIADGFRNYQKQVYAVSAEELLVDKAQLLTLSAPEMTVLVGGLRVLGANAGGSPHGVFTRRPQTLSNDFFVNLLDMSTAWKPAGDSFEGRDRKSGELKWTATRVDLVFGSNSQLRALAEVYAQDDAKEKFVRDFVAAWNKVMNLDRFDVK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: AP2D_DANRE
Sequence: MSATFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSSVAYSSSSPLTYPATGTEFASPYFPTNHQYTPLHHQSFHYEFQHSHPAVNPDAYSLNSLHHSQQYYQQLHHGEPADFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSIMSHGSQYGMHPEQRLLPGAGLGLPPPGADDLQGSVDAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPTKAVGEHLARQHTEPKEQNARKKMVLATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTILSEMLNYLEKHSANKSTGTPDTNQINSNSDKTLRKTEAPTKDGKIEKTE
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions (By similarity).
What are the official names of this protein?
Transcription factor AP-2-delta, AP-2-delta.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIC_XANOP
Sequence: MNAAPTVLQQQAQSLSEAVTQPIPGSRKIFVQGSRADLQVPMREIALTRTPTLFGGEENPPLSVYDTSGPYTDPQVAIDLAVGLAPLRAHWIAERGDTVALDGLSSSFGRGREHDARLDAVRFPARRLPRVAREGANVTQMHYARRGIITPEMEYVAIRENQRLEAVTDASLRKQHPGEAFGASIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWSIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICQIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAAEHGMDDAQALSTGMQEKSAQFLAQGAQVYRPM
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: FAEB1_NEOFI
Sequence: MMRWFLLIGLASAAATDSSASFESRCQHFHKEIHLQNVHVHSTTYVPIGSNISMAYNPPICGGTSSSSISTIEFCQVALNVTTSDKSQFFMEAWLPSNYTGRFLSTGNGGLNGCVGYGDMIYASQYGFATIGTNNGHFGDTGQYFLNNPEVIEDFAYRALHTGTVVGKALTKLFYPQGYKNSYYLGCSTGGRQGWKSIQRFPDDFDGVVAGAPAFNFVNLCNWGSRFLKITGPPDSDTFVTSAQWSIIHNEIIRQCDALDGAVDGTIEDTDLCQPIFETLICNSTAVNKTSCLTGVQANTVNEVFSAMYGLDGKWLYPRMQPGSELAASFIYYSGNGFKYSDDWFKYVVYNDSNWDHSTWTLADAAAADAQDPFQISTFDGDISGFQKAGGKVLHYHGLEDAIITSDSSKAYYKHVADTMGLSPSDLDQFYRFFPISGMGHCSPGTGAASIGQGSSTYAGDDPQDNVLMAMVQWVEKGIAPEYVRGSKKSIDGQTEYRRKHCKYPKRNRYVGPGKYTDENAWKCV
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B-1, Ferulic acid esterase B-1, FAEB-1.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DRC4_DROME
Sequence: MPPKGKKGKKGKKLPVLIDGVDTSAMTRDQLEAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDETRYELQQKDKEIEATQDLADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDKRQLRRMLRERMEMSEMQLRQMEAHFNEKLLEQRITFERERKDNEMLHEEKMIEQKAKLDLFYGTQMFEVEERKNQQIKDLQDHHDLAFNDMKNYYNDITLNNLALIGSMKEQLEHLRKQAERSDRIAADTAAENRRLKEPLEHANIQLNEYRRKLEFYERDKQQLSRLKTRNTRLEKKVKGLTWEAETLILRNDSLVAEREGLKERFNDVIVELQQKTGLKNVLLERKIAALMREDEKRSIVLHETIATCAPNFAEKLTSLDERVGNIIDEKNKIILDLRYEVTKARKAHDDLLETYECKLKQYGVPTDELGFKPIRNRDQQQLYVCGPAGIITENK
What is the function of this protein?
Cytoskeletal linker which probably functions in axonemal and non-axonemal dynein regulation.  May play a role in the spermatozoa motility (By similarity).
What are the official names of this protein?
Dynein regulatory complex subunit 4, Growth arrest-specific protein 8.
What is the protein family that this protein belongs to?
Belongs to the DRC4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum basal body.
Protein: Y1464_PASMU
Sequence: MSLHAFIQQANQFGEQRQPFFFLIDFEQQQPIICPLAQAAELGLFFAIRGQQNVNWQTEMPHKPFELHKFPISKAAYQRGFDLVQKELQKGNSYLLNLTYPTEINTNWRLEQVFQQTTAPYKLYYRDRFVCFSPECFVNIHHNQIYTYPMKGTIDATLPEAEKRLLDSDKERQEHYTIVDLMRNDLATVAEKVEVTRFRYVEKIQTQKGAILQTSSEIRGDLAENWQARIGTILATLLPAGSISGAPKEKTVQIIHAAEQRPRGYYTGIFGLFDGESLQSAVAIRFIEQVDEKLIFRSGGGITILSELEDEYQELIQKVYVPVG
What are the official names of this protein?
Uncharacterized PabA-like protein PM1464.
What is the protein family that this protein belongs to?
To the C-terminal of para-aminobenzoate synthase component I.
Protein: RL10_PYRAE
Sequence: MMLAIGKRRYVRTRQYPARKVKIVSEATELLQKYPYVFLFDLHGLSSRILHEYRYRLRRYGVIKIIKPTLFKIAFTKVYGGIPAEIAEKVRGEVGFFFTSFNPAEVIKIVAENSVRRAAQPGDKAPFDIVVPAGPTNASPGPIISKFGKLKIPTRVQEGKIWIAKDTVVAKAGQEITPEMAEVLRVVGIEPIFEQLRLLGVIWRGQRFVDISELIIDVNKYKELFETASVYARNLALNIVYPTREVLQAVIPAAHMRAVALAAKLGVVTRETLPALLSRAVAEANALAAVVAAKAPDLGISVSLPQTAAPQQTPQPTEAPKEEAQEEKKEGPSEEEIAGSLASLF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CLPP_PHYPA
Sequence: MPIGVPKVPFRLPGEEDAVWIDVYNNRLYRERLLFLGQHVDDEIANQLIGIMMYLNGEDENKDMYLYINSPGGAVLAGISVYDAMQFVVPDVHTICMGLAASMGSFILAGGEITKRIALPHARVMIHQPASSYYDGQAGECIMEAEEVLKLRDYITRVYVQRIGKPLWVISEDMERDVFMSAQEAKTYGIVDLVAIENT
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PSBM_SYNJA
Sequence: METNYLGLLATILVILVPSIFLVILYVQTSSKSES
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TTCA_BART1
Sequence: MNDVSVEYQAIEEKDVLLASKADDCHPIFRRAPSSVEFNKLRKRLLRHMRQALDDFSMLSTGKKWLVALSGGKDSYGLLALLLDLKWRGLLPVEILACNLDQGQPGFPKHILPDFLSSYKIPYRIEYQDTYSIVTDKLAQTQTYCSLCSRLRRGNLYRIAREEGCSALILGHHRDDVLETFFMNLFHGGRLAAMPGKLKNDEGDLFVLRPLVYAAEEDMEKFSQAMQFPIIPCNLCGSQDGLQRNAMKEMLKNIERQMPGRKDTMIRALANVRPSHLLDKKFFDFKTY
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_RHIL3
Sequence: MARIAGVNIPTAKRVVIALTYIHGIGPKFAQEIVAKVGIPAERRVHQLTDAEVLQIREAIDRDYQVEGDLRRDTAMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL5_PORG3
Sequence: MSATANLKKDYQERIVPALMKQFGYTSVMQVPVLKKIVINQGLGMATGDKKIIDVAVSELTAITGQKAVPTVSKKDISNFKLRKKMPIGVMVTLRREQMYEFLERLVRIALPRIRDFKGIESKLDGRGNYTLGINEQIIFPEINIDAITKILGMNITFVTSAQSDEEGYALLKEFGLPFKNAKKQN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SELU_ESCF3
Sequence: MQERHTEQDYRALLIADTPIIDVRAPVEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQELRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFIHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELATRLDAALTTQLATGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: CNX3_ARATH
Sequence: MISTLRRAVFLRRFPAVVSPIKRAFSSRIDDEFDPQIMNINELNQEMQSIFGQEPSPDGPGTMDFSELKSSKIEPLRSKNIDFRQQIEYHKSTHSSKNDSQAIEQYAKVASDMSKLTHVGIAGEAQMVDVSSKDNSKRTALACCKVILGKRVFDLVLANQMGKGDVLGVAKIAGINGAKQTSSLIPLCHNIALTHVRVDLRLNPEDFSVDIEGEASCTGKTGVEMEAMTAVSVAGLTVYDMCKAASKDISITDVRLERKTGGKSGSWSRL
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, mitochondrial, Molybdenum cofactor biosynthesis enzyme CNX3, Molybdenum cofactor biosynthesis protein C, Molybdopterin biosynthesis protein CNX3.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NADA_CLOD6
Sequence: MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLSEIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQYPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFPDKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGIIKYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKNMENEVIVEDEIMEKALNSLLNMHKLAEG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_AGRVS
Sequence: MLTLYGTELSSRLLLGTARYPSPAILAEAVRRSKTEIVTVSLRRETAGGKAGGAFFELIRDLGVRVLPNTAGCHSVKEAALTAKMAREVFRTNWIKLELIGHQDTLQPDVFQLVEAARILTEDGFEVFPYTTEDLVVGEHLLGAGCKVLMPWCAPIGSAMGPQNIPGLRAMRAEFPDLPLIVDAGIGRPSHAATVMELGFDAVLLNTAVASAADPAAMAEAFANAIDAGHGGYLAGLLEPRDMAVPSTPVIGKGVFA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGLP_BAC25
Sequence: MSEQYPVLSGAEPFYAENGPVGVLLVHGFTGTPHSMRPLAEAYAKAGYTVCLPRLKGHGTHYEDMERTTFHDWVASVEEGYGWLKQRCQTIFVTGLSMGGTLTLYLAEHHPDICGIVPINAAVDIPAIAAGMTGGGELPRYLDSIGSDLKNPDVKELAYEKTPTASLLQLARLMAQTKAKLDRIVCPALIFVSDEDHVVPPGNADIIFQGISSTEKEIVRLRNSYHVATLDYDQPMIIERSLEFFAKHAG
What is the function of this protein?
Hydrolyzes monoacylglycerols, with the highest activity occurring with 1-monolauroylglycerol.
What are the official names of this protein?
Thermostable monoacylglycerol lipase, MGLP, bMGL.
What is the protein family that this protein belongs to?
Belongs to the lipase/esterase LIP3/BchO family.
Protein: PDCD5_HUMAN
Sequence: MADEELEALRRQRLAELQAKHGDPGDAAQQEAKHREAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSEKVSEQGLIEILKKVSQQTEKTTTVKFNRRKVMDSDEDDDY
What is the function of this protein?
May function in the process of apoptosis.
What are the official names of this protein?
Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, Protein TFAR19.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: URE11_STRCO
Sequence: MPELSRTAYADLFGPTTGDRVRLADTDLFVEIEEDRSGGPGRSGDEAVFGGGKVLRESMGQGRTTRAQGAPDTVITGALIIDHWGIVKADIGIRDGRITGIGKAGNPDTMDGVHPDLVIGPETEIVAGNGKIVTAGGIDTHVHFIAPGAVDEALASGVTTLIGGGTGPAEGSKATTVTPGAWHLAWMFAALESSPVNIGFLGKGSTMSKESMRDQLRAGVLGFKIHEDWGATPAVISACLDVCEESGVQLAVHSDTLNEAGFVGDTFDAVAGRTLHAFHVEGAGGGHAPDMITAVSLPNMLPASTNPTRPHTVNTVEEHLDMLMVCHHLNPAVPEDLAFAESRIRPSTIAAEDILHDMGAISIMSSDAQAMGRIGEVILRTWQTAHVMKRRRGFLPGDTRADNLRARRYVAKYTINPAVAQGIEHEVGSVETGKLADLVLWDPRFFGAKPQLVIKGGQIAYAQMGDANASIPTPQPVLPRPMYGALGTAPATNSVNFVSEQAVEDGLPERLGLGRAFVPIRSTRGRTKADMRQNDALPRVEVAADSFAVTIDGELVEPAPVTELPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha 1, Urea amidohydrolase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.