PharMolix/UniProtQA huggingface dataset:
Protein: UBC3_YEAST
Sequence: MSSRKSTASSLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQSGDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRVKMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVILQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPHKAEDESEDVEDVERVSKKI
What is the function of this protein?
Mediates the initiation of DNA replication (transition of G1 to S phase in cell cycle).  Essential component of the E3 ubiquitin ligase complex SCF (SKP1-CUL1-F-box protein), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Involved in the regulation of methionine biosynthesis genes and in the degradation of CDC6 together with CDC4 and CDC53.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-34 kDa, Cell division control protein 34, E2 ubiquitin-conjugating enzyme 3, E3 ubiquitin ligase complex SCF subunit CDC34, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VF421_ASFP4
Sequence: MYTHVDVVGIAEASAALYVQKDRDRYSDVLTTIENFIYQHKCIITGESAHLLFLKKNIYLYEFYSNNVAEHSKALATLLYKLDPEYLTRYTVLITKIPNHWYVINVDQREFVRLYAIPAVKQHLPIPILPFYCTSALTQQELFCLGPELQLIQIYSKLCNPNFVEEWPTLLDYEKSMRTLFLEQFPQRLEMTGGKKEEEEKHESIIKKIILEMVSTRQRIVVGGYIQKNLYNHVLKNRNRLQLITSLNIYEEKDIIQQFCDSNGLKIKIRINNPLLPTNPELRRLTIYFNNTNDDDQSYLIVDMYNTGSYELVPTNQINTLDGSFLIGTPFVQARFLLVEIWVLMLIAQQTKKDTKKIIQFFINQYEMLMNSPWPSMEALFPSSSKRYLGNYVDPNALIKWAQLKLKRIPPFYPGKPDEESC
What are the official names of this protein?
Uncharacterized protein K421R, pK421R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus K421R family.
What are the subcellular locations of this protein?
Virion.
Protein: NUCS_MYCMM
Sequence: MRLVIAQCTVDYVGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWLTEEPGGDSPVWVVTNKGGEQLRISVEEIEHDSSHELGVDPGLVKDGVEAHLQVLLAEHVQLLGEGYTLVRREYMTAIGPVDLLCRDESGGAVAVEIKRRGEIDGVEQLTRYLELLNRDSVLAPVKGVFAAQQIKPQARTLATDRGIRCVTLDYDKMRGMDSDEYRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_MYCSK
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELRGLEERGVDTERLLISADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVADVLDPAVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHRIADARLLLNQALERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTIDGKRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGRDQTIVRRDVLAPS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_SINMW
Sequence: MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPLQMFENEEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PRMB_NEIMA
Sequence: MVHIMFNQAAQELTTIRDVLRFAVSRFNEAGLFFGHGTDNAHDEAAYLILHTLNLPLDMLAPYLDAKLLEAEKEEVLTVIERRAVEHIPAAYLTHQAWQGEFDFYVDERVIIPRSFIYELLGDGLRPWIEYDELVHNALDLCTGSGCLAIQMAHHYPDAQIDAVDVSLDALEVAGINVEDYGLEERIRLIHTDLFEGLEGTYDLIVSNPPYVDAESVELLPEEYLHEPELALGSGADGLDATRQILLNAAKFLNPKGVLLVEIGHNRDVLEAAYPELPFTWLETSGGDGFVFLLTREQLLGEE
What is the function of this protein?
Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.
What are the official names of this protein?
50S ribosomal protein L3 glutamine methyltransferase, L3 MTase, N5-glutamine methyltransferase PrmB.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
Protein: MIF_XENTR
Sequence: MPTFTVCTNVCRDSMPDTLLSDLTKLLAKATGKPAEYIAIHIMPDQMMSFGDSTDPCAVCSLSSIGKIGGPQNKSYSKLLCDYLTKQMNIPANRVYINFHDLNPANVGWNGSTFA
What is the function of this protein?
Pro-inflammatory cytokine.  Involved in the innate immune response to bacterial pathogens.  The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense.  Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known.  It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity).
What are the official names of this protein?
Macrophage migration inhibitory factor, MIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation (By similarity).
Protein: AIS_ECOL6
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: TIPRL_HUMAN
Sequence: MMIHGFQSSHRDFCFGPWKLTASKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRESKISSLMHVPPSLFTEPNEISQYLPIKEAVCEKLIFPERIDPNPADSQKSTQVE
What is the function of this protein?
May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A).  Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro.  The PP2A(C):TIPRL complex does not show phosphatase activity.  Acts as negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX).  May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
What are the official names of this protein?
TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP.
What is the protein family that this protein belongs to?
Belongs to the TIP41 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4MM_SINFN
Sequence: MTKTVTRAGGASGPQQFQSGGETMKYEITRRRFLAASSAVLAAPAIVTMVRPARAGTTLTLGHGAAPGNPRTVAAAKFAELVAEKTAGRVTINVAGAETLGSDAAMLTSLRTGALDVTANSQGATSALVPELAALGLPFLFENTAKAMQVLGGPVGAELVKRFEAVGVVPLDWWDNGIRHLTNSKRKVAAPAEVSGMKIRTPADPMTMDIFQALGAATEQIAFGELYVALQQGVVDGQENPLANIDSSKLYEVNKYISLTGHKWESTPFLMSQIAQARLGGDLEAVKAAAKEAGELQRKLSADKDAEVLAAFRRISAIEVTEVDREGFAKATASVVESRRSPSGISSPRSNRQPKAEALSAREHPMKSLSNLVELTARAIVWFARQVVIFSGIALMVFMTANVAARYVLAGGGFSFAQELPVLIFPWFILGGIVLAAHSGGHMAVEWIYDKLRDGARSTAFVAANLVSAGAFLMLGYQAYLVGEIAGIEHSPVLQLPNSVGYFALAVGSVLVAIVTLAVALRVLRLGWDHRTNTESGEVAL
What are the official names of this protein?
Uncharacterized protein y4mM.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MFNA_NATPD
Sequence: MQRAEPQEFSRVLSSMCTEPHPAAREAAERFLATNPGDPGTYETVSKLEREAVDMLGEVAGLPDAAGYIASGGTEANIQAVRIARNRADTRTPNFVAPASAHFSFRKAADILGVELRTAPLEDYRANLDGVAELIDSDTALVVGVAGTTEYGRVDPIPALADMAADAGALCHVDAAWGGFVLPFTEHAWDFDDADIHTMTIDPHKMGQAAVPAGGLLARGPELLDELAIDTPYLESTSQVTLTGTRSGAGVASAAAVMDELWRDGYRQQYETAQTNAHWLAAEVESRGFDVVDPVLPIVAMDLPYDLVADLRERGWRLSRTEADEARIVCMPHVTRSMLEEFLTDLDRLA
What is the function of this protein?
Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.
What are the official names of this protein?
Probable L-aspartate decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: ATPG_VIBVY
Sequence: MAGAKEIRSKIGSVKSTQKITKAMEMVAASKMRRSQDAMEASRPYAETMRKVIGHVANASLEYRHPYLDEREAKRVGYIIISTDRGLCGGLNINVFKKAVTDMQAWKEKGAEVELAVIGSKATAFFKHGGAKVAAQVSGLGDSPSLEDLIGSVSVMLEKYDEGELDRLYLVFNKFVNTMVQQPTIDQLLPLPKSDSKDMQREHSWDYIYEPEPQALLDALLVRYVESQVYQGVVENLACEQAARMVAMKAATDNATNLIDDLELVYNKARQAAITQELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBIB_YERP3
Sequence: MTPGELRRLYLIIRVFLSYGLDELIPNIRLTLPLRVGRHLFFWLSNRHKDKSLGERLRLALQELGPVWIKFGQMMSTRRDLFPPNIADQLALLQDRVASFDGALARKHIEIAMGGALETWFDDFDSQALASASIAQVHTARLKENGKEVVLKVIRPDILPIIKADVRLMYRLAGWVPKLLPDGRRLRPREVVREYEKTLLDELNLLREAANAIQLRRNFEDSPMLYIPEVYSDYCRESVLVMERIYGIPVSDIAALEDQGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPHDPLYIGIDCGIVGSLNKADKRYLAENFIAFFNRDYRRVAELHVDSGWVPRDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWTTAKPFLESWLRDQVGLPAVIRALKEKAPFWAEKFPELPELVYDSLQQHKLLQQSVEKLTIQIQGQQQRQGQSRYLFGVGATLLVSGTILFLADATEVSTGFIVAGALAWFIGWRRTC
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: P2OX_PHACH
Sequence: MFLDTTPFRADEPYDVFIAGSGPIGATFAKLCVDANLRVCMVEIGAADSFTSKPMKGDPNAPRSVQFGPGQVPIPGYHKKNEIEYQKDIDRFVNVIKGALSTCSIPTSNNHIATLDPSVVSNSLDKPFISLGKNPAQNPFVNLGAEAVTRGVGGMSTHWTCATPEFFAPADFNAPHRERPKLSTDAAEDARIWKDLYAQAKEIIGTSTTEFDHSIRHNLVLRKYNDIFQKENVIREFSPLPLACHRLTDPDYVEWHATDRILEELFTDPVKRGRFTLLTNHRCTKLVFKHYRPGEENEVDYALVEDLLPHMQNPGNPASVKKIYARSYVVACGAVATAQVLANSHIPPDDVVIPFPGGEKGSGGGERDATIPTPLMPMLGKYITEQPMTFCQVVLDSSLMEVVRNPPWPGLDWWKEKVARHVEAFPNDPIPIPFRDPEPQVTIKFTEEHPWHVQIHRDAFSYGAVAENMDTRVIVDYRFFGYTEPQEANELVFQQHYRDAYDMPQPTFKFTMSQDDRARARRMMDDMCNIALKIGGYLPGSEPQFMTPGLALHLAGTTRCGLDTQKTVGNTHCKVHNFNNLYVGGNGVIETGFAANPTLTSICYAIRASNDIIAKFGRHRG
What is the function of this protein?
Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2).  Plays an important role in lignin degradation of wood rot fungi by supplying the essential cosubstrate H(2)O(2) for the ligninolytic peroxidases, lignin peroxidase and manganese-dependent peroxidase.  The preferred substrate is D-glucose which is converted to 2-dehydro-D-glucose, an intermediate of a secondary metabolic pathway leading to the antibiotic cortalcerone.  Acts also on D-xylose, together with D-glucose the major sugars derived from wood, on L-sorbose, D-galactose and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.
What are the official names of this protein?
Pyranose 2-oxidase, P2O, P2Ox, POD, POx, PROD, Pyranose oxidase, FAD-oxidoreductase, Glucose 2-oxidase, Pyranose:oxygen 2-oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm. Note=Hyphal periplasmic space.
Protein: TRPR_SALA4
Sequence: MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLEQILLKSA
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGZ_NEIMB
Sequence: MTVPHIPRGPVMADIAAFRLTEEEKQRLLDPAVGGIILFRRNFQNIEQLKTLTAEIKALRTPELIIAVDHEGGRVQRFIEGFTRLPAMSTLGEIWDKDGASAAETAAGQVGRVLATELSACGIDLSFTPVLDLDWGNCPVIGNRSFHRNPEAVARLALALQKGLTKGGMKSCGKHFPGHGFVEGDSHLVLPEDWRSLSELETADLAPFRIMSREGMAAVMPAHVVYPQVDTKPAGFSEIWLKQILRRDIGFKGVIFSDDLTMEGACGAGGIKERARISFEAGCDIVLVCNRPDLVDELREDFRIPDNPTLAQRWQYMANTLGSAAAQAVMQTADFQAAQAFVAGLASPQDTAGGVKVGEAF
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_SALNS
Sequence: MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLVLGISGGQDSTLAGKLSQMAIAELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGTDHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLDPAIAKTIEGWYVKTEHKRRLPITVFDDFWKR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: NREC_STAAC
Sequence: MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_SHESW
Sequence: MSFKDLRSFIDHLEANGELKRISYPVDPHLEMTEIADRVLRAKGPALLFENPKNHHMPVLANLFGTPKRVAMALGKDDPLALREVGELLAFLKEPEPPRGFKDAIAKIPMFKQALNMPPKTVRNPPCQQIIKTGDEVDLTQLPIQHCWPGDVAPLVTWGLTITKGPRKSRQNLGIYRQQLLGKNKLIMRWLSHRGGALDFADFKEQFPGERYPVVVALGADPVTILGAVTPVPDSMSEYAFAGLLRGERTEVCKALSCDLEVPATSEIILEGYIDPEELAEEGPYGDHTGYYNETDKFPVFTVTHITQRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIVDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVIVDEDVNCRDWQDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGLDATNKWEGETNREWGTPIVMDPKVKQKIDSIWDELGIDDSPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDAD_PROA2
Sequence: MSFVPTKVFFTKGVGRHKEYLSSFELALREAKIEKCNLVTVSSIFPPQCERISVEEGLKSLSPGEITFAVMARNSTNEHGRLIASSIGVALPADESVYGYLSEHHPYGQTEEQSGEYAEDLAATMLATTLGIEFDPNKDWDEREGIYKMSGKIINSFNITQSAEGQNGLWTTVIACAVLLP
What are the official names of this protein?
Probable pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: RL14_HUMAN
Sequence: MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L14, CAG-ISL 7, Large ribosomal subunit protein eL14.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITA_MONPU
Sequence: MKGQTGLRSLALLYISPLYILERLPLKLSAPDTLVVRGSFIVPTEPLYPSITMVQTNLEVVDDTLHLPRILCLHGGGSNAAIFQAQCRRLIAQLRSEFRFVFAQAPFLSDAEPNVMSVYSQWGPFRRWLRWCPDHPEIRPEDAIRAIDDCLEDVKRQDDAKGATGAWVGLLGFSQGAKMCASLLYRQQIRQELRGRSFAGSDYRFGVLLAGRAPLVSLDPDLDLNSSLPDVSQITDAKYHGPSQDVLRIPTVHVHGMRDPHVDLHRQLFEEFCAPESRRLVEWDGDHRVPLKYNDVSLVAYQIRELATQTGAP
What is the function of this protein?
Esterase; part of the gene cluster that mediates the biosynthesis of the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III (PubMed:17586673, PubMed:19012408, PubMed:28238725, PubMed:19111642, PubMed:27913218).  The pathway begins with the synthesis of a keto-aldehyde intermediate by the citrinin PKS (pksCT) from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (PubMed:28238725).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (PubMed:28238725).  Mp11 collaborates with pksCT by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity).  Mpl2 then catalyzes the oxidation of the C-12 methyl of the ketone intermediate to an alcohol intermediate which is further oxidized by the oxidoreductase mpl7 to produce a bisaldehyde intermediate (PubMed:27913218).  The fourth catalytic step is catalyzed by the mpl4 aldehyde dehydrogenase (PubMed:27913218).  The final transformation is the reduction of C-3 by mpl6 to provide the chemically stable citrinin nucleus (PubMed:27913218).
What are the official names of this protein?
Esterase mpl1, Citrinin synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: YCF43_DICDH
Sequence: MALTRKPNNYLNFEFYSTRGINYSSFSLTELYSFEHFSEIRHRALYSLGFFLCTTIVIFSNIKFVVKILKNSVSMIQF
What are the official names of this protein?
Uncharacterized tatC-like protein ycf43.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: KOR2_ORYSJ
Sequence: MAEEYELNEIDDTLHGSVGSRLSLFARELKSRRSSSWHGGTALRLPKDLYESLVIHPNGRWYRIWANMMFLWSIYSTFFTPFEFSFFRGLPDQLLDLECVQLVFLADVAVHFFLAYRDPHTYRMVHDKRHIALRYIKGSFALDVLGCFPWDAIYKVTGRVEAVRWLVWVRLYRGRKVMAFFKRVEKDIRVSYLLTRIVKLITVELYCTHTAACGFYYLATTLPPAREGGTWIGSLSLGDARYINFREVDLLTRYVTSLYLAIVTMATVGYGDIHAVNTREMAFTVVYISFSIVLSAYLIGNMTALIVKGSRTERFRDRMTDLIRYMNRNRLGSAIRSQVKDHLMLQYESSYTRDRVIVDDIPVAVRSKMSQTLYLDMVSRVGLFRGCSDDFLSQIVLKLHEEFFLPGEVILEQGTVVDQIYIVAHGCLEEVANGEDGSEEIISELRPYGIVGDVAVICNIPQPYTVRVCELCSLLRIDKQSLTSILQIYFKDNSQILSNLLKGKETESKRKQLESDITYLLAKQESELVLGVNNAAYHGDIFRLKSLISAGADPSKSDYDGRTALHIAALRGYENIVRFLIQRGANVNSIDRFGNSPLLQAVKSGHDRITSLLVEHGAILNLEDAGGYLCRVVRGGRIDLLKKLLRFGISPNCRNYDQRTPLHIAAAEGLHLVASTLIESGADIQAKDRWGNTPLDEGRRCSSKPLVRILEQARTVATN
What is the function of this protein?
Probable outward-rectifying potassium channel.
What are the official names of this protein?
Potassium channel KOR2, K(+) outward-rectifying channel 2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEOD_HELAH
Sequence: MTPHINAKIGDFHPQCILCGDPLRVSYIAKNFLQDAREITNVRNMLGFSGKYKGKEISLMGHGMGIASCTIYVTELVKTYQVKELLRIGTCGAISPKVGLRDIIMVTGASTDSKTNRIRFLNHDLSATPDFELSLRAYQTAKRLEIDLKVGNIFTSDFFYSFETHAFDLLAKYNHLGIEMEAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERIESFNNMIILALEMMG
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: SYS_VIBPA
Sequence: MLDSKLLRTELDETAAKLARRGFKLDVETIRKLEEQRKSIQVEVENLQSTRNSISKQIGQKMAAGDKEGAEEIKKQIGTLGSDLDAKKVELEQVMAQLDEFTLSVPNIPADEVPDGKDENDNVEISRWGEPKTYDFDLKDHVDLGEMGGGLDFASAVKITGARFIVMKGQFARLHRAIAQFMLDLHTEEHGYTEMYVPYLVNSDSLFGTGQLPKFGKDLFHTEPLAEKVNDEEPRKLSLIPTAEVPVTNLVRDTITDEADLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITKPEDSMTALEELTGHAEKVLQLLELPYRKVVLCTGDMGFGARKTYDLEVWVPAQETYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAVGRTMVAILENNQEADGRIAIPAVLQKYMGGATHIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U20_HHV6U
Sequence: MITVFVACLFQCVSSLPAKLYIKTTLAERIGKLQTVIGIDNDIVFAYERLYEDLTLLNHTVVGETLFDLTGSLEEGKNSTVDRFLGHVVIREFHRLHAGLQYVSLRNFSVSELVCFVNNNTQLSGSYVFLAGNTTYVQIDLFNENRGFVHDLINLSSFLQNRSLHVLSFYARRFCVEDILNFYGKVVFGDSRHRPPQVFSKRDTGLLVCTARRYRPIGTNIQWSIQNQTVSDDHMTDDFIRTEIAGQLLYSYERALSRALSMTQRNFSCEITHKLLVTPALLTREDAFSFKGFVNPVKQSEDMFPRHNFPAPHRKKFNKLQLLWIFTVIPIAAGCMFVYMLTRYILFFVSGGCSLNPNRVLKRRRRNDEVPMVIMEVEYCNYEADDYMELHSVQKVRDNSIAVVCGNNSFDIERQSKISRNF
What are the official names of this protein?
Glycoprotein U20.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.