PharMolix/UniProtQA huggingface dataset:
Protein: PI42C_MOUSE
Sequence: MASSSVPPATAPAAAGGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHFFHRENLPSHFKFKEYCPQVFRNLRDRFAIDDHDYLVSLTRSPPSETEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVENEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEGPVREEESEWDGDCNLAGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFIANIFA
What is the function of this protein?
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity.  May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.  PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism.  They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3.
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI(5)P 4-kinase type II gamma, PIP4KII-gamma.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm.
Protein: RPOC_SHIDS
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYKKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFTYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTANILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PGA16_CANAL
Sequence: MRVFQIVYILIISNLIYATSGGGTSSHHHKNDNNIADNTNNNNNNNNNNNNNNITNATTTRTVTTSTKTKTHTGGGVAAMGGILGQNGWFYGDAGLMAAIFGAMLLL
What is the function of this protein?
Cell surface GPI-anchored protein required for virulence.  Mediates hyphal ramification which is important for the interaction with host cells.
What are the official names of this protein?
Virulence factor PGA16, Predicted GPI-anchored protein 16.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: FSHB_PHOSU
Sequence: MKLIQLCILFWCWRAICCQGCELTNITIAVEKEECRFCISINTTWCAGYCYTRDLVYKDPARPNTQKICTFKELVYETIRLPGCAHHSDSFYTYPVATECHCGKCDSDSTDCTVRGLGPSYCSFGE
What is the function of this protein?
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer.  Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways.  Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
What are the official names of this protein?
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted. Note=Efficient secretion requires dimerization with CGA.
Protein: SLB_TRIAB
Sequence: NFSCPPDWYAYD
What is the function of this protein?
Potent platelet activator that aggregates platelets via both GPIb (GP1BA/GP1BB) and GPVI (GP6).  Alboluxin induces a tyrosine phosphorylation profile in platelets that resembles those produced by collagen and convulxin, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), LAT and p72SYK.  Inhibition of alpha-IIb/beta-3 reduces the aggregation response to alboluxin, as well as tyrosine phosphorylation of platelet proteins, showing that activation of alpha-IIb/beta-3 and binding of fibrinogen are involved in alboluxin-induced platelet aggregation and it is not simply agglutination.
What are the official names of this protein?
Snaclec alboluxin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_MESCR
Sequence: MDTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDAESKVACETCTKTNLVMVFGEITTKANVDYEKIARDTCRNIGFVSDDVGLDADNCKVLVYIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVAAGLARRCIVQISYAIGVAEPLSVFVDTYGTGKISDKDILKIVKETFDFRPGMIANNLDLLRGGNRYLKTAAYGHFGRDDADFTWEVVKPLKWEKPQE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA5_RAT
Sequence: MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
What is the function of this protein?
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
What are the official names of this protein?
Annexin A5, Anchorin CII, Annexin V, Annexin-5, Calphobindin I, CPB-I, Endonexin II, Lipocortin V, Placental anticoagulant protein 4, PP4, Placental anticoagulant protein I, PAP-I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, VAC-alpha.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: RTEL1_AEDAE
Sequence: MPEYQINGITVNFPFEPYQVQRDYMSRVIECLQNSTNGVLESPTGTGKTLSLLCSSLAWVLHKKAQVQANMRTNITDLKEFEMVQRKKLGGDGGSGMEELLDKLHDGCGPEGAKWGVPKIVYASRTHSQLTQVMQEMKNTSYSFMKGVILGSRDQLCIHPEVSKEEGNSTKTNLCKAKVQSRTCSFYSRVESCKERPEVVSNVIMDIEDLVKVGTKVRACPFFLSKELIESADILFMPYNYLLDPKARKANNLEISNTIIILDEAHNVEKMCEESASMQIRSTDIALCIDDVTSIMKVMDHSVAIPEDDETKKDFTIDDLALLKEMLLQLEKTVDSIPVMFSQGGNTFPGTYIFEIFEKANIKEGNYHIIAQLLENIIQYIATITEKNNFVRRGGGLQILAEALSIIFAGSGPEYRASIDKCYKVHIEIEEQKKTRGNVKQADGWTATKQLVPSVKANAKVVSFWCFNPGFGMRQLLGRNARSIILTSGTLAPLKPLISELDIPIAVRLENPHIIDGSQVCVKIVGQGPDKESLNSSYGNRDNPKYISSLGRTILSFCPIIPGGLLVFFPSYPLLNKCQEAWQETGIWAQISRTKPIFVEPRGKDQFLNTMSEYYQKINDPDGKGAVFMAVCRGKVSEGLDFADMNGRAVIITGLPFPPLKDARVILKKKYLQEVRTRENEIISGDEWYSLEAARAVNQAIGRVIRHKNDYGAILLCDNRFHNHRQKSQLSSWIQKHLNTNQHQNFGPIIGELSRFFRNAEKILPQSKLSRNIVTLVQEPTPLIECNIPGALIVNRDTKRKLDDIRNNFVQIENSNQVTSTFRISDYEQAPSQSASNEPKNFLSRLNTQVHSIDFNDMTTYSMPSSSQGALVGIHKRERSTGSDNSIFSQTQTATQKKRKVVLIPQQVINLTSDDEDPGRTGDDPTRQAPEDRVELIKVIKTSIPLAKYQAFLSTLTNYNKDRNFDRLMEGLLVAFDRPELYYLLRAMRRFVKGDHEARFDAKIKEVCGR
What is the function of this protein?
ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
What are the official names of this protein?
Regulator of telomere elongation helicase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_STRR6
Sequence: MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQLEQTARLKEVKKQIARIKTVQSEAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y1635_LIMF3
Sequence: MLVTTTERIPGQEYEVLGECFGVTTQSRDIISNFGAGLKNLVGGEIKGYTKMLTTSRQEAIDRLKEEAAAMGADAVVMMRFDSGSIASDMQSVVAYGTAVKFIEKIRVRPLT
What are the official names of this protein?
UPF0145 protein LAF_1635.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: DEOD_STRPG
Sequence: MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNMPERNMALGKLGVKAIEMEAAALYYLATQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: VL2_HPV25
Sequence: MARARRVKRDSATNIYRTCKQAGTCPPDVLNKVENTTIADKILQYGSAGVFFGGLGISTGKGTGGTTGYVPLGEGPIRVGGTPTVIRPSLVPDTIGPSDIIPVDTLNPVEPTSSSIVPLTESSGPDLLPGEVETIAEIHPGPVVPSTDTPVTTTSRGASAVLEVAPEPTPPSRVRVSGTQYHNPSFQVITESTPAQGESSLADHILVTSGSGGQTIGGTASDLIELQEFPTRYSFEIDEPTPPRQSSTPLQRIRTALRRRGGLTNRRLVQQVPVEDPLFLSQPSRLVRFQFDNPVFEDEVTQIFEQDLNDFQEPPDRDFLDIRSLGRPQYSETPAGYVRVSRLGQRRTIRTRSGAQIGSQVHFYRDLSSINTEDPIELQLLGQHSGDATIVQGLTESTFVDVNVDENPLAEDFSISAHSDDLLLDEANEDFSGSQLVVGGRRSTSTYTVPRVETTRSASYYTQDIQGYYVSYPEDRDTSKDIIYPMPDLPVVIIHTYDTSGDFYLHPSLTTRRRRKRKYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: RECO_LACLM
Sequence: MRDAETQGLVLYSRNYKEKDKLVKIFTESFGKRMFFVKNFGKSPYASSLQAFTDGKLTATINDGGFSFIEDVSEVVVYKNISADIFINAHASYIISLADAAISDNQYDPALYGFLKRSLELLDQGFDMEVVTNIFELQVLHRFGVSLNFSECAFCHKTVGPFDFSYKFSGCLCPRHFDEDLRRSHLDPNVIYLINLFQEISLDELKKISIKAEMKAKIRQFIDGLYDEYVGIHLKSKKFLDGMSGWADIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: A1HB1_LOXIN
Sequence: MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMEKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (PubMed:15234562, PubMed:9790962, PubMed:16934304).  The level of enzymatic activity is high according to Tambourgi and colleagues or low according to Felicori and colleagues (PubMed:15234562, PubMed:16934304).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  It induces complement-dependent hemolysis, dermonecrosis, vascular permeability and platelet aggregation (PubMed:15234562, PubMed:9790962, PubMed:16934304).  Both C5a and the membrane attack complex may play a role in the induction of dermonecrosis.  MMP-9 and MMP-2 produced by skin fibroblasts can also contribute to proteolytic tissue destruction.
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaIA1bi, LiD1, LiP1, P1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 1, SMD 1, SMase D 1, Sphingomyelinase D 1, recLiD1.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PTA1_YEAST
Sequence: MSSAEMEQLLQAKTLAMHNNPTEMLPKVLETTASMYHNGNLSKLKLPLAKFFTQLVLDVVSMDSPIANTERPFIAAQYLPLLLAMAQSTADVLVYKNIVLIMCASYPLVLDLVAKTSNQEMFDQLCMLKKFVLSHWRTAYPLRATVDDETDVEQWLAQIDQNIGVKLATIKFISEVVLSQTKSPSGNEINSSTIPDNHPVLNKPALESEAKRLLDMLLNYLIEEQYMVSSVFIGIINSLSFVIKRRPQTTIRILSGLLRFNVDAKFPLEGKSDLNYKLSKRFVERAYKNFVQFGLKNQIITKSLSSGSGSSIYSKLTKISQTLHVIGEETKSKGILNFDPSKGNSKKTLSRQDKLKYISLWKRQLSALLSTLGVSTKTPTPVSAPATGSSTENMLDQLKILQKYTLNKASHQGNTFFNNSPKPISNTYSSVYSLMNSSNSNQDVTQLPNDILIKLSTEAILQMDSTKLITGLSIVASRYTDLMNTYINSVPSSSSSKRKSDDDDDGNDNEEVGNDGPTANSKKIKMETEPLAEEPEEPEDDDRMQKMLQEEESAQEISGDANKSTSAIKEIAPPFEPDSLTQDEKLKYLSKLTKKLFELSGRQDTTRAKSSSSSSILLDDDDSSSWLHVLIRLVTRGIEAQEASDLIREELLGFFIQDFEQRVSLIIEWLNEEWFFQTSLHQDPSNYKKWSLRVLESLGPFLENKHRRFFIRLMSELPSLQSDHLEALKPICLDPARSSLGFQTLKFLIMFRPPVQDTVRDLLHQLKQEDEGLHKQCDSLLDRLK
What is the function of this protein?
Essential in pre-tRNA processing.  Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation.
What are the official names of this protein?
Pre-tRNA-processing protein PTA1.
Protein: PSD_BREBN
Sequence: MGKKLLPGLIHRLPQNAMSRTMGKITATPFSRLAIQRYIKHYQIDTSIIEKPASEYRTLKEFFSRRLKPAARPIAPGPDTIVSPVDGTVSQLGDICEGTLIQAKGKDFSVSELLGGSEEEAKRYYGGKFITIYLSPRDYHRIHMPVTGDLSSYCYLPGRLYPVNKLGIENVDRLFARNERLVTHIKTDSLGDMALVKVGALFVGSVKVCYNTATTNIKHGRQTHEKIAGTPRYEKGSELGWFEFGSTVILLLESNELEWATGVEKGKSLLMGQALATKKA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: G6PI_AYWBP
Sequence: MLKLNLEGIYNFLDWRKHTQTYAPQIKSIHQKLHQDKQLKEKYLGWLELPLHFDFKEIEKMKQLKNFHPNLDVLVVIGIGGSYLGAKAGIEFLQTPFKKTKPEILFAGHQVSGNYLTNLLHFLKNKNWAINVISKSGTTLEPALAFRILKKEIEEKYGKQLAKNRIFVTTDSQKGVLLNLALKEGYQTFVIPDSVGGRFSVFTSVGILPFVFANLDVASMMKGALQSYHDTFQEDLLQNQAYKYALARYLFHTQQNKKMEILVSYEPNLLSFSEWWKQLFAESEGKEEKGLFVGATNNSTDLHSLGQFIQEGTKMLFETVLNVSSIKDDCVVPHILNELDNLNYVAGKTYSQINQKILQATRQAHIEGKVPNLEIVIPTLDAYHFGYLAYFFQKACAMSGLLLGINPFNQHGVEIYKQKMFALLKP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_PHOPR
Sequence: MLQLDEILANATTAIETAASLVALDEVRVQYLGKKGELTSQLQSLGKLPPEERRTAGQEINKAKGAVQQAIAARKDALQRAELETKLAAETIDVSLPGRRIENGGLHPVTRTVERIEQFFGELGFSTESGPEIEDAFHNFDALNIADDHPARTDHDTFFFNPDLMLRTHTSGVQIRTMEHGKPPFRFIAPGRVYRNDYDQTHTPMFHQVEGMLVDENVNFAQLKGILNEFLCNFFEEEVEVRFRPSFFPFTEPSAEVDVKRKDGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATM3_SOLTU
Sequence: MATTKSFLILFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYLEHGPHIFNYSGSIIGPMYDGKYLLQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPIYFPPHYFITHTSNGDIYEFNLVDGGVATVGDPALLSLSVATRLAQEDPAFSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAQEAAKWGPLRWMLAIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLVQVGETLLKKPVSKDSPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin group M-3.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: ODPA3_ARATH
Sequence: MATAFAPTKLTATVPLHGSHENRLLLPIRLAPPSSFLGSTRSLSLRRLNHSNATRRSPVVSVQEVVKEKQSTNNTSLLITKEEGLELYEDMILGRSFEDMCAQMYYRGKMFGFVHLYNGQEAVSTGFIKLLTKSDSVVSTYRDHVHALSKGVSARAVMSELFGKVTGCCRGQGGSMHMFSKEHNMLGGFAFIGEGIPVATGAAFSSKYRREVLKQDCDDVTVAFFGDGTCNNGQFFECLNMAALYKLPIIFVVENNLWAIGMSHLRATSDPEIWKKGPAFGMPGVHVDGMDVLKVREVAKEAVTRARRGEGPTLVECETYRFRGHSLADPDELRDAAEKAKYAARDPIAALKKYLIENKLAKEAELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFADPKGFGIGPDGRYRCEDPKFTEGTAQV
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha-3, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATOD_ECOLI
Sequence: MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGVRDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGTLIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCDTLGNLTYQLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQESK
What is the function of this protein?
Coenzyme A transferase which is involved in short-chain fatty acid degradation and catalyzes the activation of short-chain fatty acids to their respective CoA thiolesters (PubMed:1103739, PubMed:3025185).  During acetoacetate degradation, catalyzes the transfer of CoA from acetyl-CoA to acetoacetate by a mechanism involving a covalent enzyme-CoA compound as a reaction intermediate (PubMed:1103741).  Utilizes a variety of short chain acyl-CoA and carboxylic acid substrates but exhibits maximal activity with normal and 3-keto substrates (PubMed:1103739).
What are the official names of this protein?
Acetate CoA-transferase subunit alpha, Acetoacetyl-CoA transferase subunit alpha, AA-CoA transferase subunit alpha, Acetyl-CoA:acetoacetyl-CoA transferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane associated.
Protein: COAD_CAMHC
Sequence: MRTNCIYPGTFDPITNGHLDVIKRALRIFDNVIVAVAKSDNKKPFFELDKRVEMVKEATKSLENIEVIAFENLLVDFAKSQDTCFVIRGLRAVSDFEYELQLGYANRSLWDKFETIYLMPTIKYSFISSSIVRSIFEHGGDISHLVPKEILPFLEDKKC
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NET3C_ARATH
Sequence: MVREEEKSRWWWFESHKSSKHSQWLQSTLAEIDAKTKAMLKLLDGNADSFAQRAETYYKKRPELISFVEDFYRAHRSLAVNFDHLKSSDHYGSRSAKVPQQSMESVCDSNSHFEDADSEIEDPLQDDASAADCKEDETWQLEQERLKLIEETDALRKQLLDKDEEKREVIRQLSLTLETLKDENLSLKRRLAHHSLKQRTVLEFKPLNKFFGKLFYIMCDGNKVL
What is the function of this protein?
Plant-specific actin binding protein.  Part of a membrane-cytoskeletal adapter complex that forms a bridge between the endoplasmic reticulum and the plasma membrane.
What are the official names of this protein?
Protein NETWORKED 3C.
What is the protein family that this protein belongs to?
Belongs to the NET family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane. Cell membrane. Note=Localized in immobile puncta that associate with ER membranes and ER-plasma membrane contact sites. This association is independent of F-actin.