PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_ECO81
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRIFAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDQRSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_MYCPU
Sequence: MAKTKAGGSTRNGRDSKGRRLGAKLGDGQFALAGSIIYRQRGTKIFPGQNVGRGNDDTLFMLVDGYVKYEKRRNRKYASVYQEKK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CDRB_CLOAT
Sequence: MVHNDLDFIFYNNLKHSSGAIEHLGDNLTGDGDXDDEEIIIDLSLIPQNISRINFTVTIHEAGERSQNFGQVSNAYVRVVNSDNSQELLKYDLGEDFSIETAIVVAEIYRHNGEWKFNAIGSGFQGGLAALCRNFGLNV
What is the function of this protein?
Not known; could confer methyl methane sulfonate (MMS), mitomycin C (MC), and UV resistance.
What are the official names of this protein?
Chemical-damaging agent resistance protein B.
What is the protein family that this protein belongs to?
Belongs to the CAPAB/TerDEXZ family.
Protein: YP17A_YEAST
Sequence: MDLRMLYFLIYFAVTHLPSLISLLLTNNYILTLLFIVLHILFIWLPWYTSCFSYSVGSKFT
What are the official names of this protein?
Putative uncharacterized protein YPR170W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURP_PYRHO
Sequence: MVRIATYASHSALQILKGAKDEGFGTIAFGKPRVKLLYTKYFPVADYFLEGDYPEDKLLELDAVVIPTGSFIAHLGVELVEKMRVPYFGNKEVLKWESDRSLERKWLEKAKLTLPRIYEDPDDIDRPVIVKPHGAKGGRGYFIAKSSKDFWEKAEKFLGIRSKEDLKNVQIQEYVVGVPIYPHYFYSKITGELELMSIDRRYESNVDAIGRIPSREQLDLDLDVTYTVVGNIPLVLRESLLMDVIEAGERVVKASEELMGGLWGPFCLEGVFTPDMEFVVFEISARIVAGTNLFINGSPYTWLKYDEPMSTGRRIAREIKIAIEEGKLEEVVT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RAC4_ORYSJ
Sequence: MASSASRFIKCVTVGDGAVGKTCMLICYTSNKFPTDYVPTVFDNFSANVVVDGTTVNLGLWDTAGQEDYNRLRPLSYRGADVFVLAFSLVSRASYENVMKKWLPELQHYAPGVPIVLVGTKLDLREDKHYLLDHPSLVPVTTAQGEELRKHIGATCYIECSSKTQQNVKAVFDAAIKVVIKPPTKQRDRKKKKTRRGCSFFCKGVMSRRRLVCFK
What is the function of this protein?
Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
What are the official names of this protein?
Rac-like GTP-binding protein 4, GTPase protein ROP4, OsRac4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with the membrane when activated.
Protein: IMDH_SHIFL
Sequence: MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: K2C8_XENLA
Sequence: MSVRSTKVTYRTSSAAPRSGGFSSFSYSGAPMASRASSASFSLGSSYGGASRFGSGYRSGFGGAGVGSAGITSVSVNQSLLAPLNLEIDPSIQQVRTEEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWNLLQNQKTTRSNMDGMFEAYISNLRRQLDGLGQDKMRLESELGNMQGLVEDFKNKYEDEINRRTELENEFVLLKKDVDEAYMNKVQLEARLEALTDEINFLRQLYEEELREMQSQISDTSVVLSMDNNRSLDLDGIIAEVRAQYEDVANKSRLEVENMYQVKYQELQTSAGRYGDDLKNTKTEISELTRYTTRLQSEIDALKAQRANLEAQIAEAEERGELALKDARNKLAELEAALQKAKQDMSRQLRDYQELMNVKLALDIEIATYRKLLEGEESRLESGFQNLSIQTKTVSGVSSGFGGGISSGFSNGVSSGFGGGYGGGYGGGYSYSSNVSSYIGDTKTSKRRLLVKTVETKDGRVLSESSDVFSKP
What is the function of this protein?
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Protein: ARAB_ECOLU
Sequence: MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSAEQRAAVVGIGVDTTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHTPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: TXB2A_SCODE
Sequence: MFQFCLLILLLAPGRFFSALGKPQETLTVENREGSDSKAIPTCREASFCAFLQKNPIDSNLDVLPTCTCTGGTTCSHSWDPNDGKSITEGNKQFKFCSNVPDTIKHECSAEEKALTGIFEEDKVTKKHLAYYGFLHCICPEHSDYPENSYDGTETVEGDKKITTEYYHCERLKTCKSDDTCHALAIGETKKIYYKDCNCPEGQTCPFELKSAYKTEYKETTDKFTTYSMRCQ
What are the official names of this protein?
U-scoloptoxin(11)-Ssd2a, U-SLPTX(11)-Ssd2a, Toxin SSD16.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_LEGPA
Sequence: MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSNSLLRNFNDGQQIVATGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKLASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQTAPQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETDFTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQLRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U518_DROWI
Sequence: MSWLRSSPLRQSLTRTTSSGNGIRPIDAATDCDPRACYDSFCKHWQQAYDIIQHSSAPAPTHDDVLGVVSHLDYMVTLLLVELHNCNKISLADSNAPPTAPCLEYLLSENLLDKLYEWAATTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQIQNGNVPPPKSGTTTNFIIFSLLIPYVHREGSIGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEINSIDWHRITPDDVTEIPELNLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTNIDSQISAMSYLDLILRSITEPGLLRAFVKFLLDTEKFDGERILDALVERLNSPDGNLCMVTMALFDTLLGLHCEDLMLELMLKYMLPGKHVPISHRHKINKIDPYLNSTEFFLELTPDVMKRARDLARPKSVNEHQQESALPNELSLPSLPSPVMSKTIGANWNYYGLHTGDSLYANLQAYLFEAHWRIAQCQRDCLKWANSYRYQKWPRQGQPQNRLHNHALELAKQFFIEFGGEGIGGLGGGAAIASEAGEKQLDSLQSIGESSGYESFKWRPADEDVSASSGNGTGSVVVGDHPGHDVTISESDVDGHNISSSLSNSSGRRESWRISHNTRNELLLTDLDFSEDLFAQGTVSLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIVITSDTPSFHQVLRILKQQIDAELPVTEDSLEIIDVARSSLIDREFRLVNARKGNENSPLHQQQSLQHPHHLQPLPAPQQTGAGAQQRSAYATLSAATPVQATPFSAYDPFKRSNNSRRSISKSITSMFSRKSTLPAPAIAPTPASSGLSQIYAFFTGAASTIMGNNNQQSSNQTHLNSSSSSAVTTCETSLSTQPHATGPGSAQLRTTSSTISTSSGTTAGSGGGGGSGSNSSFSIGGSTQTLSAHSNNTTNSSSTLHGGLDGIGPPTGSFNSEPVSLDSVGSSMGIIANTSGTERSRDLALCAVLLDEWLKELAAIAQEQSIVLVTDQWL
What are the official names of this protein?
FHIP family protein GK23746.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: THYX_CAMJR
Sequence: MQITLLFHTPLSVCSHATRTCWQSFEKGDCGGEKDKELIDRVGNKFKHASTLEHLNYTFYIQGISRACLQEVARHRHTSPSVKSTRYTLKELRNEAEFKIGDFENASRYLVLCGNEEVDNASIKALENLRTILQKSISLDIAKYCLPESYKTELTLTINARSLQNFISLRSSKSALWEIRNLANALFEALPQEHKFIFEHCLHKDIE
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: KARG_LIOJA
Sequence: MADLAELWEKVSSNKDSKSLLKKHLTKEVYEKLKDKKTKFGGTLADCIRSGAKNLDSGVGVYASDPEAYTVFQDLLGPVILDYHKITELKHPACDFGDLSNLGFGDFDPSGDWIVSTRVRVGRSHASFGFPPTLNKEQRVEMQRVTQGALEGLTGELKGKYYPLEGMTPDVQKQLTEDHFLFNDSDRFLKAASGYDDWPTGRGIFFNDNKTFLVWVNEEDHIRIISMQKGGDLAAVYKRLVGGIKELEKKLEFARLPNLGYLTFCPSNLGTTLRASVHIKIPKVAKKPEFKEICDKLNLQARGIHGEHTESVGGVYDISNKRRMGLSEIEAIQEMRKGVEEIIKLEKAA
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: SMG_XYLF2
Sequence: MKESILAVLLYLFEYYFSENADLVRDRDSLQNSLIQVGFSPAEINKAFEWLDALAANRPTLTNPRVNGPVRVLHGPELDKLDVESRGFLLFLEQQGILNTEQRELVLDRAMALDQEELDLDDMKWVVLMVLFNQPGAEAAYAWMETQMFGNEPEQLH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: GLVA_BACSU
Sequence: MKKKSFSIVIAGGGSTFTPGIVLMLLDHLEEFPIRKLKLYDNDKERQDRIAGACDVFIREKAPDIEFAATTDPEEAFTDVDFVMAHIRVGKYAMRALDEQIPLKYGVVGQETCGPGGIAYGMRSIGGVLEILDYMEKYSPDAWMLNYSNPAAIVAEATRRLRPNSKILNICDMPVGIEDRMAQILGLSSRKEMKVRYYGLNHFGWWTSIQDQEGNDLMPKLKEHVSQYGYIPKTEAEAVEASWNDTFAKARDVQAADPDTLPNTYLQYYLFPDDMVKKSNPNHTRANEVMEGREAFIFSQCDMITREQSSENSEIKIDDHASYIVDLARAIAYNTGERMLLIVENNGAIANFDPTAMVEVPCIVGSNGPEPITVGTIPQFQKGLMEQQVSVEKLTVEAWAEKSFQKLWQALILSKTVPNARVARLILEDLVEANKDFWPELDQSPTRIS
What is the function of this protein?
Hydrolyzes maltose-6'-phosphate and trehalose-6'-phosphate.  Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent maltose phosphotransferase system (PEP-PTS).  Is also able to significantly catalyze the hydrolysis of both 6-phospho-alpha- and 6-phospho-beta-glucosides containing activated leaving groups such as p-nitrophenol and does so with retention and inversion, respectively, of the substrate anomeric configuration.
What are the official names of this protein?
Maltose-6'-phosphate glucosidase, 6-phospho-alpha-D-glucosidase, 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: YA037_HUMAN
Sequence: MQDVHTKSIACDGDLLPVLQENSISFQMLSLEMSGSFHSSPALENATITILHVSLLSFFRGIQAPCRGSPLLVTDSPGG
What are the official names of this protein?
Putative uncharacterized protein HSD52.
Protein: LYS2_LUCSE
Sequence: MLKLTLTILAAVLLVTPAFGKVYTRCSLAREMHTLGVPKNQLARWTCIAEHESAYNTKAVGSMNSNGSRDYGIFQINNYYWCSPPSGAFSYNECKIKCADFLVDSIEPAVKCAQLVLRQQGWSAWSTWKYCDHTLPSIDDCF
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function (Probable).  Shows antibacterial activity against Gram-positive bacterium M. luteus but shows no activity against Gram-negative bacterium E. coli (PubMed:25098233).  Likely to play a role in the eradication of ingested pathogens during their passage through the intestine (Probable).
What are the official names of this protein?
Lysozyme 2, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPMI_PIG
Sequence: MKLGSAIPWALLLSTXTLVSTAQNKGSDDCGGFLKNYSGWISYYKALTTNCVWTIEMKPGHKIILQILPLNLWTIEMKLEVRDQRAGPDNFLKVCGGTTFVYQSSSNVATVKYSRESHHPASSFNVYFYGIPQGAKA
What is the function of this protein?
Inhibitor of sperm motility.
What are the official names of this protein?
Seminal plasma sperm motility inhibitor.
What is the protein family that this protein belongs to?
Belongs to the spermadhesin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CADN2_DROME
Sequence: MVDPLKIFWVLTNSTYLVTKFVRIGIADKNDSPPYFDRFLYETEIDENADLQSTVLTVNAKDHNESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPTLPENVSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEVQEHQRFKLDTDTGILTMRAGTRRGRYQLRFKVYDREHGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLERFRNKLAELLYTDRDNVDVFSVQLKEGSPYPLTDVHFAARSATQQPYFKAVRLNGVVQMHREEIEKDVGLNITMVNINECLHEGKGKCGSNSCTSKVELGKKPYTVSVNRTALVGVRLDISAQCVCRARNFTHQDHNCRTHLCYNGGRCVETRNGPKCVACPVGYNGPRCQQSTRSFRGNGWAWYPPLQLCQESHLSLEFITRVADGLILYNGPIVPPKPEETVISDFIALELEQGYPRLLIDFGSGTLELRVKTKKTLDDGVWHRLDIFWDTENVRMVVDFCRTALVSEMEDGTPPEFDDNACQARGQIPPFAESLNLNQPLQLGGLYRQHFDQTLYNWQYAFSSKGFDGCIRNVIHNSEHYDLAFPALARNSFPACPQTDEVCLKTEHTARCWEHGNCVASLVQAKCHCQPGWMGPGCNVPTIPTTFKAQSYVKFALSFEPDRFSTQLQLRFRTREQGGELFRVSDQHHREYAILELRRGHLQFRYNLNSMRNEEQLLTLTAIAVNDGQWHVIRISRYGSAALMELDGGESRRYNESFHFTGHQWLTIDKQEGVYAGGKAEYTGIKTFEVQSDFQRSCLDDIRLDGKHLPLPPAMNGTQWGQATMARNLERNCPSNRPCSNVICPDPFDCVDLWNEYECTCSEGRIMSSDTKGCVDRNECLDLPCLNGATCINLEPRLRYRCICPEGYWGENCELVQEGQRLKLSMGALGAIFVCLIIILILALIFVLYSRKRKTTKKKKRSGPEKDVRETVISYEDEGGGEDDMTAFDITPLQIPISAQGGPPDIAACKMPIIYPVMTLLPPGQELNVAYLMEERKQRIDKDNNAPPFDDLRNFTFEGSGSIAESLSSLASGTDDENQDFNYLQNWGPRFNALAAMYVHDKAKASSQLPSDGGGGSGDGPGPGASSSSPLGGGGTGGGSGIPGNVLAVVATGSGAGPGGGGGSSGLMPLPEVDKVVL
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells (By similarity).
What are the official names of this protein?
Putative neural-cadherin 2, Cadherin-N2, dN2-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYM_LEGPC
Sequence: MTSERKMLVTSALPYANGHLHLGHLVEHIQTDIWVRTHKMLGIQCISVCGDDAHGTPIMLKAEQLGITPEALTAEIKLSHEKDFKAFAIDYDYYHTTHSPENQALATTIFERLQAGGDIVKKTIRQFYDPVKQMFLPDRYVKGTCPKCAAVDQYGDNCEVCGATYSPTDLINPVSVISGASPVEMESEHYFFDLPRYEELLKDWTRKGHLQTEVTNKLSEWFEAGLKQWDISRDAPYFGFPIPGVPDKYFYVWLDAPIGYMASFKKYCDERGVSFDEFWDKASKTELYHFVGKDIVYFHALFWPAMLAASGFRTPTAVYTHGFLTVEGQKMSKSRGTFIEARAYLAHLHPEYLRYYFAAKLNGRVDDLDLNFDDFVNRVNADLVGKVVNIASRCAGFINKRFDNRLSSELINQKLYNDLLSAREFVIDAFVSRDYARAIRQIMDCADKVNQYIDANKPWVLAKDESKLNEVHAICTMGINLFRILITYLKPVLPMMAKASEEFLNSEPLHWGSIDKPLLNHRINTFKPLMVRVEKEKIEAMLVQSKESLMTTPIKENTPVEDSNLISIEDFAKVDLRIAKIVNAEPVEGADKLMRLILDLGDAQKQVFAGIKKAYDAEELIGRLTVMVANLEPRTMRFGVSEGMVLAAGDGQGIYLLQPDAGAFPGMKVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOC2B_DROMO
Sequence: MDHIKLIRNKIDINHIHQLIIDQSCGACSVFVGTTRDHFEGKKVISLEYEAYESMALKEMGKICSELRIRWPTLKHIAIYHRLGSVPVAEESVVIAVSAPHRPAALESVSFAVDKLKSSVPIWKKEIYENDQIGEWKANMECPWPQFTETSSNAFEYSLCKIERQVENISESKLVQIRVSDIELTRRIKCFLKRKRDEINLHNIIDFKQQLRDSPRAESMLPKDSCARTQSILVKQQQSISHIKVHRAFEDRRQTRPDYSSQLNKLMATKHKHCELVKSNVLKNARLQNIEEYMRITPDDEDNIYNRIKNIENRILILESTSPEYKYYIKLGKESNNINKKESKKGLYQSDRLSEFISGIKRQYEL
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated Mocs2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOF_AQUAE
Sequence: MRSYPAIPRIYAETTLNMLLKRAKKPRVHSIDEYLKDGGYQALEKALNMSPEEIIDWVDKSTLRGRGGAGFPTGKKWKFAVQNPGPRYFICNADESEPGTFKDRIIIERDPHLLIEGIIISSYAIGANEAYIYIRGEYPAGYYILRDAIEEAKKKGFLGKNILGSGFDLEIYVARGAGAYICGEETALIESLEGKRGHPRLKPPYPVQKGLWGKPTVVNNVETIANVPFIISMGWEEYRYIGPSDYAGPKLFPVSGKVKKPGVYELPMNTTLREVIFKYAGGTLGNKKVKAVFSGALDCFSSEELDIPMDYSPLGFGGTGTVIVLTEEDDIVEAALKIAEFYEHETCGQCTPCRVGCYEQANLLEKIYKGEATEQDWEGFDFVNRNIQPTSICGLGAVAGRLIRQTLEKFPEEWEKYRKKSASLPL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: BXI1_YEAST
Sequence: MSGPPPPYEEQSSHLYGQPASSQDGNAFIPEDFKYSTVVISCEPIIRQRFMHKVYSLLSCQLLASLSFCYWASVSTSLQNFIMSHIALFYICMVVSLVSCIWLAVSPRPEDYEASVPEPLLTGSSEEPAQEQRRLPWYVLSSYKQKLTLLSIFTLSEAYCLSLVTLAYDKDTVLSALLITTIVVVGVSLTALSERFENVLNSATSIYYWLNWGLWIMIGMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFRKVYPDEEVRCAMMLYLDIVNLFLSILRILANSNDDN
What is the function of this protein?
Links the unfolded protein response and programmed cell death and mediates mitochondrial-dependent apoptosis (PubMed:21673659, PubMed:21673967).  Induces cell death and disruption of the mitochondrial transmembrane potential via the mitochondrial phosphate carrier MIR1 (PubMed:21673659).  Dispensible for starvation-induced autophagy (PubMed:21926971).
What are the official names of this protein?
Bax inhibitor 1, BH3 domain-containing protein BXI1.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Note=Translocated from predominantly vacuolar sites in healthy cells to mitochondria upon apoptosis induction.
Protein: ENY2_DROWI
Sequence: MTVSNTVDQYTVLTGDRSKIKDLLCNRLTECGWRDEVRLLCRNILMEKAVAGAVTSNSNLTLEQLITEVTPKARTLVPDAVKKELLMKIRTILTENETEGTDNHDDDEDDEDENGTEDN
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes.  The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  Required for nuclear receptor-mediated transactivation.  Involved in transcription elongation by recruiting the THO complex onto nascent mRNA.  The AMEX complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  AMEX participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Enhancer of yellow 2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm.
Protein: ACDH_BURPS
Sequence: MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEYALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGYRLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: MOCOS_EMENI
Sequence: MNLSKGTAAAYCSGYSEDVDVIREREYPLLKDTTYLDHAGTTLYANSLIHSFGRDLTGNLYGNPHSMSASSQLSAQRVDDIRLRALRFFNADPDEFDLVFVANATAGIKLVADALQNSPQGFWYGYYVDAHTSLVGVRELAKMGSRCFVNEDEVDSWISGLGSRREESLGLFAYPAQSNMNGRRVPMRWCEQIRAQKENADNMIYTLLDAASFVSTSPLDLSKIAAAPDFTVLSFYKIFGFPDLGALIVRKSSGDVFKHRKFFGGGTVDMVLTDGNPWHAKKQSSIHQSLEDGTLPFHSIIALDSAFETHGRLFRSMENVASHTRFLAKRLRDRMNALKHYNGTKVCQLYMSPNSSYDDASSQGPILAFNLRNSRGMWIGKSEVERLASIKNIQIRSGTLCNPGGTALSLGWTGADMLRHFSAGMRCGDDHDIMDERPTGILRISLGAMSSLTDVDTFIAFLEEFYVDKPPEGLPVPLTGNVSLHQPSFYVESLSVYPIKSCGAFRIPDGQRWEVRREGLAWDREWCLVHQGTGITLNQKRYPRMALIRPTLDLERCLLRITCGEANSRDGKTLEISLNRIGTNSLTTSLCQNASKPSTVCGDKVVLQAYTSPAVSRFFTDFLGVPCTLARFPPQSSTRFHSRATAAINRDQNYSQKQSPSMPGSFPQAPSSPDPYPTPILLSNESPLLLISRSSVNRLNESIKSASQPCSNPGSAASKKAVAADVFRANVVVAENISTAERPYIEDTWASLSIGSGPEQLRFDVLGSCERCQMVCVDQYTGQRGDEPYATLAKTRKIDRKILFGRHISPVGRPKDAENGCLGTIMVGDAVTPSYDNES
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.