PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_METST
Sequence: MTEEEKTKSEAEEIEQNNKEEEQEKSVEELLEEKEQEIQQYKDKLQRIHADFENFKKRSIKEKQEFVKFANEGLILKVLEAYEDLERALEVKEDKNLREGVELIYKKLTKILEDEGVEPIETKNQKFDPYKHEALMTEDNDDYENNEIIQDLQKGYTLNSKVIRYSKVKVCKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_EDWI9
Sequence: MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADGRIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATVHAYQHFGIDRAE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MAST3_HUMAN
Sequence: MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD
What are the official names of this protein?
Microtubule-associated serine/threonine-protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: AGRG2_RAT
Sequence: MLFSGGQYSPVGRPEEVLLIYKIFLVIICFHAILVTSLKENAGNSSLLSPSAESSLVSLVPYSNGTPDAASEVLSTLNRTEKSKITILKTFNASGVKSQRNICNLSSICSDSVFFRGEIVFQHDDHYNVTQNQDIVNSTFAGVLSLSELKRTELNKTLQTLSETYFIVCATAEAQNTLNCTFTVKLNETMNVCAMMVTFKSVQIRPMEQCCCSPRTPCPSSPEELEKLQCDLQDPIVCLADQPHGPPVSSSSKPVPVVPQATIFSHVASDFSLAEPLDHALMTSSTPSLAQETRLPSPQPTISLTSSPAIDLPVQHVVASSSLPQTDLSHTLSPVQSSIPSPTTAAPSVPEKVVAISTPPGETVVNTSSVPDLEAQVSQMEKALSLGSLEPNLAGEMVNRVSKLLHSPLALLAPLAQRLLKVVDAIGLQLNFSSTTISLTSPSLALAVIRVNASNFNTTTFAAQDPANLQVSLEAQAPKNSIGAITLPSSLMSNLPASEVELASRVQFNFFETPALFQDPSLENLSLISYVISSSVTNMTIKNLTRNVTVALKHINPSQDDLTVKCVFWDLNRNGGRGGWSSDGCSVKEKRMNETICTCSHLTSFGILLDLSRTSLPPSQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYNARGFCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGSYGKFPNGTPDDFCWINSSVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNLTFMYLFAIFNTLQGFFIFIFYCAAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSNSLQSSCNSTNSTTLLVNSDCSVHASGNGNASTERNGVSFSVQNGDVCLHDLTGKQHMFSDKEDSCNGKSRMALRRTSKRGSLHFIEQM
What is the function of this protein?
Orphan receptor.  Could be involved in a signal transduction pathway controlling epididymal function and male fertility.  May regulate fluid exchange within epididymis.
What are the official names of this protein?
Adhesion G-protein coupled receptor G2, G-protein coupled receptor 64, Rat epididymis-specific protein 6, Re6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: RIMP_BACFN
Sequence: MIEKRTVCQIVEEWLEDKDYFLVEVTVSPDDKIVVEIDHAEGVWIEDCVELSRFIESKLNREEEDYELEVGSAGIGQPFKVLQQYYNHIGLEVEVLTKGGRKLSGVLKDADEEKFVVTVQKKVKPEGAKRPQLVEEDETFTYDDIKYTKYLISFK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYPC_BACMM
Sequence: MSNINQMPREEGIDSTWRLMEEGYMYILNRRHSFNSDIFETRLLGKKAICMGGKEAAEIFYDTEKFKRKDAAPNRVVQTLFGKNGVQALDGQTHKHRKEMFMSIMSPDELEKLTDITKKQWEIAVDKWEQMDKVILYEEAKEIMCRTACQWAGVPVQENEVKRLTKNLGAMFESAAAVGLKHWLGRHARNYEEIWIEELIDRVRDGKVNPPENTTLHKFSWYRDLEGNLLDTETAAVEVINILRPIVAIAIFINFIALALHHYPEEKEKLKSGDKKYSQMFVQEVRRFYPFFPFVVALVKKDFTWKGYKFEEGTLTLLDLYGTNHDPEIWKNPDVFSPDRFAKWEGSPFSFIPQGGGDYFMGHRCAGEWVTIEVMKVSLDYLTNRMDYEVPDQDLSFSMASMPSIPHSKVVIKNVKKRI
What is the function of this protein?
Fatty-acid peroxygenase that catalyzes the hydroxylation of dodecanoate with formation of 2-hydroxydodecanoate and only trace amounts of 3-hydroxydodecanoate.  Cannot use hexadecanoate as substrate, and from tetradecanoate, forms only a small amount of the 2-hydroxylated form, with large amounts of substrate remaining.  Can further convert 2-hydroxydodecanoate into 2,3-dihydroxydodecanoate and 2-hydroxydodec-2-enoate, the latter product likely leads to undec-1-en-1-ol via oxidative decarboxylation.  Thus, this enzyme seems capable of both desaturation and decarboxylation reactions in addition to hydroxylation reactions.
What are the official names of this protein?
Fatty-acid peroxygenase, Cytochrome P450 peroxygenase CYP152K6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: H3L3_LILLO
Sequence: MARMKLNARMSTGGKAPRKQLAYKAVRKAAPPTIGVKLPNSYRPGDQTVCKPAPPTDGVKEPHRYRPGKMGLREIRKYKKNARFFISKLPFHRLVRKITQNLKAHLRFQSTAMPAPEEVSEAYLVKLFEDAIHAKRVTLVPKDIQLARCIGGVLA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-like 3, Histone leH3, Late embryonic-like histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NORW_KLEP3
Sequence: MSDGIVIIGSGFAARQLVKNIRKQDTQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLTLQSAGEFAEQYNLRLFPHTWVSDIDAENRLVKSQDNQWRYDKLVLATGATPFIPPVPGRELMLTLNSQREYGAAQSQLHDAKRVLIVGGGLIGCELAMDFCRAGKAVTVVDNSASVLAALMPPEASSRLQHRLTEMGVHLMLKAQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPETSLARHAGLQINRGVVVNNQLQTSDPAIYALGDCAEINGTVLPFLQPILLSAMCLSKNLLAQAGELKLPPMLVKVKTPDLPLHLAGDTRRDDLTWNIVAAKEGLVAKGVDGENQLRAFVVSEDKMKEAFALLKQLVS
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTR2_HALSA
Sequence: MGSGLVARIRGSYGTKLTLALVVVVVLSVGVGTFVYQQTTTQLETDVRADLTGSADARADHLDAWLSNARGQTQLASRHPVLASGNDTAITRYLEGLAASDERPDGVVAAHVYNTSTTTIEASSADAFTGVNPREQGAPFATDPPSFATTSDVVVAAPFTVPAADFPVLSVLSPIPGTTDKALIYMVNVNTLTDDFGQNVAGSTTTVVSADGTYVSHPDQDRVLTGHDGPSRLLNQSRTQPAYIDANGTVTAAAPVDGAPWSVLVRAPHDRAFALGDFVASSLVGLVLITIVSLSLIGVTVGSTTVTALRQFSRRADEMAAGDLDTDIDTSRNDEFGTLAESFRSMRDSLSESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETARALESAAADYEEALTAVADGDLTRRVDASRDHDAMARIGHALNDMLDDIETSVAAATAFSDHVSDAAQRVEADAGDAIDAGTDVSTAVDEISDGATEQTDRLHEVAGEVDDLSASAEEVAETVASLADTAGQAASAVDDGRQATEDAVETMDDVADDAEAAADAMDALDSEMADIGEIVDVIADIADQTNMLALNASIEAARTGADGDGFAVVADEVKTLAEESRDAAEDIESRLLALQGQVSDVADEMRATSDTVSDGRATVGDAATALDDVVSFVADTDTAAGEIRAATDRQAHAASRVASAVDEVAGISQETAAQATAVADSAATQTDTLSSVDDAAADLADRAAALDDLLAEFDAHDDTEPEDY
What is the function of this protein?
Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor.  Responds to light changes through the variation of the level of methylation.  Also acts as a chemotransducer.
What are the official names of this protein?
Sensory rhodopsin II transducer, HTR-II, Methyl-accepting phototaxis protein II, MPP-II.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDC_SHESA
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSVVANATTNHSADVPEADTSVPAALTATQNLITVKTDQLDVQINPVGGDIVFAALVSHKLEQGKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFAANKTEFTLADGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNVDIDYKINNTSAAPLQVQMYGQIKQTIKPSESSMMMPTYRGAAFSTQDVRYEKYKFEDMSKSNLNQPTLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSALSDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGVAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLQDLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGASMFVMQKMQPIAPTMDPMQVKMMQWMPMIFTVFFLWFPSGLVLYWLVGNIVAIIQQKIIYAGLEKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_FRAT1
Sequence: MTLQQIKEIYSRPLTELILQALEIHNKNFGNDIELCSLKSIKTGTCPEDCKYCPQSGHYNTSIEKHKLLDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKDFDQVAEIITEVKNLGLETCVTLGSINADEATKLKQAGLDYYNHNLDTSREFYPEIITTRKFEERIETIRNVANADINVCCGGILGMGESLDDRFNLLLELLQLPAAPKSIPINTLIPIKGTPLGDKYTNAQIDSFELVRFIATTRILFPQARLRLSAGRENMSLETQTLCFLAGINSIFYGNKLLTENNATVNSDNFLLAKLGLKSNAELC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ORRM6_ARATH
Sequence: MAISLGRVVVPSCTISGDRLFIPNFSAICSVSCGRINVGTGVISARRRRDIGGVLISSCLSTDSSSSPPSSSSGPKTKLYVSGLSFRTTEDTLRDTFEQFGNLIHMNMVMDKVANRPKGFAFLRYETEEEAMKAIQGMHGKFLDGRVIFVEEAKTRSDMSRAKPRRDFPKPQSKPRTFRTW
What is the function of this protein?
Involved in C-to-U editing of chloroplastic RNA.  Required for the photosynthetic subunit psbF transcript editing in chloroplast.
What are the official names of this protein?
Organelle RRM domain-containing protein 6, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURC_STRP1
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANLFVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTD_LACJO
Sequence: MAGWFTETQNKAYKDAMSALNANPTIDLENSYVPLQNQYKDIRVDEHPEYLHDKEWAQATYNGDLVGIKTSDVMLGVYVPKEEDVGLGMELGYAMSQGKYVLLVIPDELYGESINLMSWGVADNVIKMSELATFDFNRPRYNFYDGAVY
What is the function of this protein?
Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base.
What are the official names of this protein?
Nucleoside deoxyribosyltransferase, N-deoxyribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside deoxyribosyltransferase family.
Protein: ASNA_ECOL6
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_YERE8
Sequence: MICPVIDLAQQLIKRPSLSPNDAGCQEIMIQRLEAIGFTVEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWCSPPFEPTIRDGMLYGRGAADMKGSLAAMVVAAERFVAAHPNHKGRLAFMITSDEEAKAINGTVKVVNALMARHERLDYCLVGEPSSTDRVGDVVKNGRRGSITANLHIHGIQGHVAYPHLADNPVHRAIPALNELVTTQWDEGNEFFPATSMQIANLHAGTGSNNVIPGEFYVQFNFRFSTELTDSMIKQRVEALLERHQLDYTLEWVLSGQPFLTARGALVDAVVNAVEHYAEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVHAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: NUOH_CAUVC
Sequence: MQAFFANPAVSWTLLTTGGILLVVIWVLLSLAFLLLADRKIWAGVQMRKGPNVVGPFGLLQSFADFFKFVLKEIVIPAGADKVVFILAPLISLILAFVGWAVVPFAPGWVVSNLNVGILYLLAMSSLGVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGLIIITVILLAGSMNLSTIVEKQSGWIWNWNVFGGGLNNLVLLPVMVVAMGMFYISALAETNRPPFDLPEAESELVAGYQVEYSSTPYLLFMVAEYSNIVLMCAMISVLFFGGWNPGFPTDFLSSWHPFAANLFLALVFYAKICFWFFMFAMAKAIVPRYRYDQLMRLGWKVFLPTSLVLVAAVAAWRVFGPAA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEC13_CRYNB
Sequence: MCLWPLIQSAQASKPVPVETQHEDMIHDAQLDYYGKRLATCSSDRTIRIFNVIKGEAKGEPVILKGHTAAVWQVSWAHPSFGSILASCSYDGRVFIWKEVGQGQGKGSGGELQDGWERIKEHTLHTASVNSIAWAPYDLGPILACASSDGKVSVLSFQNDGSIEVNIFPAHGTGANAISWAPSVLSTVSGVSRSQQPSNSLAPQKRFVTAGSDNLIRIWGFDEEQKKWTEEETIKGHEDWVRDVAWAPNIGLPGMYIASASQDRTVLIHSRPSPSSSWTSAPLLPSLPQSQDPHFPDAVWRVSWSLAGNVLAVSCGDGKVSLWKEGVGKGWECVSDFSS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: RH38_ORYSJ
Sequence: MADGGKPPTPEKKSWADVEEEEEAKAKAAAAAEAASSSSSNEPAVDAQAKQIEALSLSVPEEHGGSGGGGDDQGPPLLDDSDESQIQAVTSGGTVYESAAAFEDLKLTPELLKGLHDEMGFSRPSKIQAVTLPMILTPPYKDLIAQAHNGSGKTTCFVLGMLSRVDPNRKVTQAICICPTRELAQQNKSVLMRMGKFTGITCACAIPPAQKDYVPIAKMPKITDQVVIGTSGTLMKWINHKKILTNDIKILVFDEADHMLAEDGFRSDSERIMRDIQRSAGGCQVLLFSATFNERVKDFVTRVIKDGNQIFVKKEELTLEKVKQYKVQVPDERAKIAVIKDKIFEFGQKVGQVIIFVRTKQSTKDVHNALTLEDYVCSSIQGSLDQSEREKIIQEFKNGYTKVLISTDVLARGFDQAQVNLVINYDMPIKFGTRDEPDYEVYLHRIGRAGRFGRKGAVFNLLCGETDNTVMRKIETYFQHNVPEVRNWQSEEDFERALKDAGLVE
What is the function of this protein?
ATP-dependent RNA helicase essential for mRNA export from the nucleus.  Plays an important role in the positive regulation of CBF/DREB transcription factors (By similarity).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 38.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL6_MYCS5
Sequence: MSRVGNRVLVVPAGVTVDISASNFVSVTGKLGKLERAFSPKVKITLQDNTLTTQRLNEEKATKQLHGTTNALLANMLKGVSEGFQINLEIKGVGYKAELKGNKLVVAAGYSHLVTLDIPSNVEVKVPKPVEISVKGIDKQAVGAFAAVVREIRKPNPYSGKGISYKGEKIRRKEGKTASK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MUTS_FRAT1
Sequence: MLTKRFYNLAIMQDISNHTPMIQQYLKIKSQYQDILLFYRMGDFYELFFDDAKKAAELLDITLTARGKSNGESIPMAGVPYHAAEAYIAKIVKKGLSIAICEQTGDPNTSKGPVERQVTRIITPATVSEEAFLDNNQDSILVSIFEKNNKYYLAYTSYTQGKIYLVKTLTSLNELKNTVLKLSPQEIITNSRELAQQNPFKKPIKALEEWYYSNFEAKKYINDSLDTNIANNILNLYKNDQLTTIGSILSYLTNILKDTPRHITDISYEQEQDTLNIDINSRINLELDNNSKSSLLSIIGKCKTSLGSRLLKRYFSNPTRNLNILATRHSIINSLGENQHFLKIQDVLSYISDIERIISRVALGTVKPKDLVALRDSLEQLPILKKLLSEKNTPEITNINNRIHQLDELVTLLDKAIIENPPTTIRDGGVIKEGFDKELDELKSIKDNSYDFLIKFEELQKQKTGISTLKVGYNSVHGYYIELSKQHADKIPTEYVRRQTLKASERYITEELKNFEDKVLSSKEKALAREKLIYDTLLKKVIEYYKQIQETAASIAEIDVLANFAERAIKLKLSQPKFNNLAKLELKEVRHLAIEHNIDEPFIPNDTLLSKDTNTLQIITGPNMGGKSTYMRQVAQLIFLAYIGSFVPASYADICDIDTIYTRIGASDDISSGRSTFMVEMTETAYILNNASAKSLVIMDEIGRGTSTFDGLALAKACAEKFAQIGAFTLFATHYFELTELAKQYPNVCNIHFEAKEYKDNIYFMHKAVTGAAKKSYGIQVAKLAGISQDVLESAKQNLYNLEKKQQLTESTQVQAQFQLEPTTQNPLQQKLDAIDINTITPLEALNILFELKKTLI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RUVA_BACVZ
Sequence: MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGFSTREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEALEALRVLGYAEKEIKKVLPHLKEETALSTDQYVKKALQKLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GPMA_MYCPA
Sequence: MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSLLRRAITTAHLALDAADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAAAVASQGRG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.