PharMolix/UniProtQA huggingface dataset:
Protein: L_DOBV
Sequence: MEKYREIHRDLQSFPVGSLTAVECIDYLDRLYAIRHDIVDQMIKHDWSDNKDSEESIGKVLLFAGVPNNVITAMEKKIIPDHPSGKTLRSFFKMTPDNYKITGSTIEFVEVTVTVDVDKGIREKRLKYEAGLKYIEQELHNHFLRGDIPQPYKITFQVVSVRTDGSNISTQWPSRRNDGVVQYMRLVQAEISYVREHLIRQEERAALEAMFNLKFNISNIKNQPYYIPDYRGIPLIHPNINDLVVYMRDWLSKSHKFSFHEGKVPAVFDCFNENELEHAVKYPISRHPRNFLLIQCSLLSSYNPATILSDQVDSRRACNSVLNLIPETPTSFLIHDMAYRYINLTREDMVSFYAPKTQFIPTQNVKEPGTFKLTANSMRPESKAMLDMLGSHEPGEKKGALIESLNLSSHIVQSECVSLITKILSDLELNISEPTSHGSFTTKHTYVDNVLEKFFQNEIQRYLLDVLKKTTAWHIGHLIRDITESLIAHSGLKRSKYWSVHAYNNGNVILFILPSKSLEVAGSYIRFVTVFRMGPGLVDKDNLDTILTDQDVTWGVSKVMSIDLNRLLALNIAFEKALIATATWFQYYTEDQGQFPLQHAIRSVFAYHLLLAVCQKMKLCAIFDNLRYLIPAVTSLYSGFPSLINKLFERPFKSALEVYVYYNIKSLLVALAQNNKARFYSKVKLLGLTVDQSTVGASGIYPSFMSRVIYKHYRSLISEVTTCFFLFEKGLHGNMNEEAKIHLETVEWALKFRQKEDQYGESMVENGYTIGELNDNQDLVEQQLYCQDAVELAAVELNKILSTKSQVVANSILNKYWEVPYFSQTRNISLKGMSGQVQEDGHLAASVTIIEAIRYLSSSQNNPSVLQLYEETRKVKAQARIVRKYQRTEADRGFFITTLPTRCRLEIIEDYYDAISKNVAEEYISYGGERKILCIQSALEKALRWASGESFIELSNGKFIRMKRKLMYVSADATKWSPGDNSAKFRRFTAALHNGLPDDRLKNCVIDALRNVYKTDFYMSRKLRAYIDNMNGHEPAVKNFLEFFPDGHCGEVRGNWLQGNLNKCSSLFGVGMSLLFKQLWNELFPELDCFFEFAHHSDDALFIYGYLEPIDDGTDWFLYVSQQIQAGHLHWFSVNTEMWKSMFNLHEHVLLLGSIKISPKKTTLSPTNAEFLSTFFESCAVSIPFIKILLGSLSDLPGLGYFDDLAAAQSRCVKAMDLGASPQVAQLAVALCTNKVERLYGTAVGMIKHPSTYLQVKHGDTPIPLGGSGAMSIMELATAGIGMSDKNLLKRALLGYIHKRQKNMAYILGLFKFLMNLSKDTFQHERLGEFSFIGKVQWKIFIPKSEFEFFDMYTPKFLKLWSEQHVTYDYIIPKGRDNLLIYLVRKINDPSIVTAMTMQSPLQLRFRMQAKQHMKVCKLDDDWVTFREILAAANSFAQLYEVTQEDLDLFQTLTSCTFSKEYAWKDFLNGVQCDVIPTKQIQRAKVARTFTVREKDQIIQNSIPAVIGYKFAVTVDEMSDVLDSAKFPDSLAVDLKTMKDGVYRELGLDISQAEVMKKVAPMLYKSSKSRVVIVQGNVEGTAEAICGYWLRTMSLVKTIRVKPHKEVLKAVSIFNRKEDIGQQKDLAALRLCIEVWRWCKANNAPYQEWFHALWFEDKTFSEWLDRFIRVGVPPVDPEIQCAALMIADIRGDLSVLQVQANRRAYSGKQYDAYCVQTYNEETKLYEGDLRVTFNFGLDCARLEIFWDKQTYILETSITQKHVLKIMMDEVTKELLRCGMRFKTEQVSNVKHLVLFKTEAGFEWGKPNIPCIVYKNCALRTGLRANQTVNHKFMISIKDNGLRAIAQYDDESPRFLLAHAFHTIRDIRYQAVDAVSNVWFIHKGIKLFLNPIISSGLLENFMKNLPAAIPPAAYSLIMNRAKISVDLFMFNDLLRLINPSNTLDLSGLQPTEDGFSTVSSMSSRLWSEEVSFVDEDEEIDDEFTIDLQDVDFENIDVEADIEHFLQDESSYTGDLLIMSEETEVKKMRGIIKLLEPVRLIKSWVSKGLCIEKVYSPTNIILMTRYLSKNFNFSGRQVSLLDPYDLTEFESIVKGWGECVVDQFSTFDQETQLLVSQKGICPEDVVPDSLFSFRHTIVLLRRLFPQDSVSTFY
What is the function of this protein?
RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate (By similarity).  During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral transcription.  Cleaves ssRNA substrates but not DNA (By similarity).  Seems to downregulate the expression of its own and heterologous mRNAs through its endonuclease activity (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, RdRp, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the Bunyavirales RNA polymerase family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region.
Protein: MEND_LACLM
Sequence: MTNEYLAPFVDELFNLGVREAVFSPGSRSTALAMLFEEYKKYDTYVNIDERSAAFFALGIAKANRRPVVLVCTSGSAAAHHFPAITEAKTSRIPLIILTADRPAELQFVGAPQTLDQTRFFGNFVNHFENLEAPQPQAKNFWTYPRKVAQRAFLSALDQMAGPVQINIPLRDPLVPELKSENYEKGRSKLPFKFFKGQQSASFDEALLSSKTLILAGANSSENYSESLLKLAEHLKAPILADPLSNLRNHNSPFVMDSYDAFLANDDLKTDLKAESILLFGQMPVSKRLQQFIALNDDAEFIQVDPALAYRNPSLTTTITVQSNVATFANSIQKVNQDFSYLEKWQKAQEKMRHQLEKVAQEENPFEGRFVQELQKHLKALDAQLLVSNSMEIRDIDYWWKKEDSKVRILGNRGVNGIDGTESTALGIATTGKPTVLLTGDLSMLHDLNGLIIGKTHELNLTIVLFNNDGGGIFHHLAQKGVPNFDYLFSTPHGLNFEGLAELTGLDYHLVSNYADFGQQFETSIRQPGIHLLEIKTDKDLSLALHKKYTAYEN
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL14_BRUSU
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYASVGDIIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: BCHB_CHLL3
Sequence: MRLAFWLYEGTALHGISRVTNSMKGVHTVYHAPQGDDYITATYTMLERTPEFPALSISVVRGRDLAQGVSRLPATLQQVEEHYHPELSVIAPSCSTALLQEDLHQLAAQSGVPQDKLMVYAVNPFRVTENEAADGLLTALVKRYAAEGPKTAAPTVNLLGFTSLGFHLKANLTSIRRLLTTLGVKVNVVAPWGAGIADLKRLPEAWLTIAPFREIGQTAAAYLEETFGVPTEYGTPLGVEPTLRWLRAVIEKLNTVGAKEGATPIAMPELHAFSLDGMSAPSGVPWFARTADMESFSNKKAFVFGDATTTVAMVKFLRDELGMQIIGAGTYLERHADWVRKELDGYLPGALMVTERFQDVAQVIEDEMPDLVCGTQMERHSCRKLDVPCMVVCPPTHIENHLLGYYPFLGFDGADVIADRVYISCKLGLEKHLIDFFGDAGLEYEEPSASSENGSAPLSAGTATPAAAPEEGGMAWTDEAETMLKKVPFFVRKKVRKNTENFAEENGESRVSVEVFRRAKESLGG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: COXX_BRUMB
Sequence: MSLVEKNTASEDAFALSEATARDYLVLLKPRVMSLVVFTGLVGLVLAPGHMNPVLAVISILCIAVGAGASGALNMWYDADIDAVMKRTRKRPIPAGIIAPNQVLAFGLTLSAFSVMTLGLMVNWLAAALLAFTIFFYAVIYTMWLKRSTPQNIVIGGAAGAFPPMIGWAAATGEITWDSLVLFMIIFLWTPPHFWALSLFTTNDYEAARIPMMPNVKGELSTRRQALFYAVLMAPVGVLPWVMGFAGMFYGVVSTLLGLAFVYYAWRLWAADSQPQMLAAARKLFRFSLLYLAGIFAVLLFEALTFKLLAAFGVF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYAY_YERPB
Sequence: MNDSEFHQLADQLMLYIEETLDGFTGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFNYRDGHWYCSRSGEEFFAKLSEAATTQAGEEVSFSE
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ARNC_PSEPF
Sequence: MRPYPIHCVSIVIPVYNEEDSLPELLRRTEAACKQLRHDYEIVLVDDGSRDASAQLLEEAASVVDSPFVAVILNRNYGQHAAIMAGFEQCKGDVVITLDADLQNPPEEIPRLVAEAEKGFDVVGTVRGNRQDSALRRYPSKLINLAVQRSTGVAMSDYGCMLRAYRRTIIDAMLACRERSTFIPILANSFARHTTEIPVAHAEREHGDSKYSPMRLINLMFDLITCMTTTPLRLLSIVGFAMAGLGVLFAAALIFMRLAFGAGWAGDGLFVLFAVLFVFTGGQFIGMGLLGEYLGRMYSDVRARPRFFIEKVLRGHPATPAPAITVDGLTSNSTSDQVLS
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2068_ARCFU
Sequence: MVFMDDLEEIRRRKLMELQRQKELEELQKEEMRRQVEAQKKAILRAILEPEAKERLSRLKLAHPEIAEAVENQLIYLAQAGRIQSKITDKMLVEILKRVQPKKRETRIIRK
What are the official names of this protein?
DNA-binding protein AF_2068.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: Y128_TREPA
Sequence: MEFLRATASREVDVNSGWGYGSGVERGFLCEGDVRACLVPASHFVRAGTAPGTTPGTAAACLFVPPYVLGVTPAGTLPFGLPSQSVLGGLRLAPVHASSLLEGLGATIFFRCNAP
What are the official names of this protein?
Uncharacterized protein TP_0128.
Protein: RS19_CHLP8
Sequence: MPRSLKKGPFIEFKLEKRILDMNSKGERKVVKTWSRSSMISPDFVGHTVAVHNGKTHVPVYVTENMVGHKLGEFAPTRLYRGHAGGKAEKGGSAPRKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: AUSE_PENBI
Sequence: MAPMNPPRLQRFPATASADQIFAAFKEDGCVVIEGFIPPDQVARFSQEVNPAMEKITVEVTNDGNSNDRTKRFSKCAIASPTFRNEIIESDLMHELCDRIFSNPGEGMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECIMNFFCAVTPFTEENGATRLAPGSHLWPEFTQINERDCPQFGKIETAPAIMQPGDCYLMSGKVVHGAGHNTTTTDQRRALALSIIRRELRPVQAFSLSVPMKLAREMSERSQTMFGFRSAVQHCDGDMVHFWGNDGKDIAHHLGLEAPSVHI
What is the function of this protein?
Multifunctional dioxygenase; part of the gene cluster A that mediates the biosynthesis of the fungal meroterpenoid acetoxydehydroaustin (PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (By similarity).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (By similarity).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG then modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:29076725).  The cytochrome P450 monooxygenase then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:29076725).  The hydroxylation catalyzed by ausR permits the second O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:29076725).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end product of the Penicillium brasilianum austinoid biosynthesis clusters is acetoxydehydroaustin (PubMed:29076725).
What are the official names of this protein?
Multifunctional dioxygenase ausE, Austinoid biosynthesis clusters protein E.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: PHS_PROM9
Sequence: MEPYLLRDEELKELVVKIPGWEIKSEQIQREFSFANFIEAFSFMTKVALICEKYNHHPNWENIYSKVIISLNTHDLGGITNLDQTLASEINKIFDQ
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: DYP_THEFY
Sequence: MTEPDTERKGSSRRGFLAGLGAAALTGAGIGMAAGEVLRPLLPDSDPAASPEAEQRLRMAAQRADATAAPQPGISGPAPAFVHVIALDLAEEARKNPDTARDSAAAALRSWTELAARLHEESPHDIAEGAASAGLLPASLMVTVGIGGSLLSAIDAEDRRPDALADLPEFSTDDLHPRWCGGDFMLQVGAEDPMVLTAAVEELVAAAADATAVRWSLRGFRRTAAAARDPDATPRNLMGQIDGTANPAQDHPLFDRTITARPADNPAHAWMDGGSYLVVRRIRMLLTEWRKLDVAARERVIGRRLDTGAPLGSRNETDPVVLSARDEEGEPLIPENAHVRLASPENNLGARMFRRGYSYDQGWRDDGVRDAGLLFMAWQGDPATGFIPVQRSLADQGDALNRYIRHEGSALFAVPAAREGRYLGQDLIEG
What is the function of this protein?
Peroxidase that is able to convert a large number of compounds, but its physiological substrate is not known.  Shows high reactivity towards anthraquinone dyes (e. g.  Reactive Blue 19) and a modest activity towards standard peroxidase substrates (such as guaiacol and 2,6-dimethoxyphenol) and azo dyes (e. g.  Reactive Blue 5).  Is also able to oxidize aromatic sulfides enantioselectively, resulting in the corresponding (R)-sulfoxides, but with a poor efficiency.  Does not display catalase activity.
What are the official names of this protein?
Dye-decolorizing peroxidase Tfu_3078, DyP, Peroxidase Tfu_3078.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_CHLFF
Sequence: MEQTLSIIKPDSVGKAHIGEIVAIFEKAGFRIAAMKMVHLSAKEAEGFYAVHKSRPFFQELVDFMISGPVVVMVLEGDNAVVRNREIMGATNPQEAAQGTIRAQFGESIGINAVHGSDSLENAAIEISYFFSKTEIVNSVE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP6_TRIVH
Sequence: MRFSVLLTGLAAAGSIATAERTCGAVPPRAYEKEFTEALNSLSPEAASADLTAGITIDTYLHVLTSGQTGNIPDSQLQAQINAMNQHYSQAGVQFRLVKATRTDNANWASGRDEAGMKKALHMGTYSSLNIYFIPNLSSGLLGICYFPRANPSQTTIIMDGCMVRSGTVPGGETTNYNQGKTATHEVGHFLGLYHVFSENGSCVDADMVADTPAQSKKTSGCPSSQDSCPGGGVDSIHNYMDYSYDVCMNQFTPGQANRIAQSWRAFRAGH
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity).
What are the official names of this protein?
Extracellular metalloprotease TRV_06892.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: JAL45_ARATH
Sequence: MSKKVTIAYGGSNGNKFDDGVYEGTYDGVRKLIVGEDFHGIVYLKIQYVKNGDVVVKEHGRARGTHITETEFEVKCPDEYITSIWGTCRNDHHRYKSTGGRTFEQLTAADKYDINLAAKMGTPMYWNTVSELQFKTSHGRTSEQFRMPGTGGSNGVSWDDGAYDRLSKLCVGEDAHCVSSVEFHYVKGNDRITHCHGKDSKEHDKDGFISSLTFKTSMNRSSEKFGKPVGTKFQLEAKGFDKIVGFRGRSSVNRINALGANFAVVVVPPVKKLNAKGGVLGNEWDDGIHDDARMITFKLYFNKEYITSVEGHYGKRLAAPNASASAMSSFFTGYMTMLKFNTNRTTYQVLSHSPEYTYEGTSFKLEEKDHKIVGFYGKTEVSLNQIGVYVKPIANA
What are the official names of this protein?
Jacalin-related lectin 45.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: FLAAL_BRAHW
Sequence: MFAQDAAQTGEQTTQNQGENGNNFVTEAITNYLIDDFEFANTWQASMPRDYGVVSIIRREGGPADVVAEGAENNKYILGAKVEYFRTGYPWFSVTPPRPVKIPGYTKELSVWVAGRNHNNRMSFYVYDVNGKPQAVGNEALNFMGWKNITVQIPANIRQEEFRGQVEQGISFMGIHVKVDPRDSYGKYYIYFDQLMAKTDMYLETYREEDDPLDTW
What is the function of this protein?
Might be part of the flagella.
What are the official names of this protein?
Putative flagellar filament outer layer-like protein, P-H42.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: CDK18_RAT
Sequence: MNKMKNFKRRLSLSVPRPETIEESLTEFTEQFNQLHTQRNEDGRDEPGQLSPGVQYQQRQNQRRFSMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGINLLTSLLLYESKSRMSAEAALSHPYFQSLGERVHQLDDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF
What is the function of this protein?
May play a role in signal transduction cascades in terminally differentiated cells.
What are the official names of this protein?
Cyclin-dependent kinase 18, Cell division protein kinase 18, PCTAIRE-motif protein kinase 3, Serine/threonine-protein kinase PCTAIRE-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: Y371_STRPN
Sequence: MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVSWLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDFVKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRLTFDELNELAENFSEN
What are the official names of this protein?
UPF0398 protein SP_0371.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: SYUA_PONAB
Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGATQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
What is the function of this protein?
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (By similarity).  Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (By similarity).  Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (By similarity).  Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (By similarity).  This chaperone activity is important to sustain normal SNARE-complex assembly during aging (By similarity).  Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (By similarity).
What are the official names of this protein?
Alpha-synuclein.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane. Nucleus. Synapse. Secreted. Cell projection, axon. Note=Membrane-bound in dopaminergic neurons (By similarity). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity).
Protein: NRDR_CARHZ
Sequence: MRCPFCGNENTRVIDTRAAEDGFAIKRRRECENCSKRFTTYERLDDRPLIVVKKDGSKQLFDKHKIYTGLLKACEKRPIAESKLLEIAEEIERELKNRLEQEVTSLEIGEMVMSRLKKLDEVAYVRFASVYRQFKDVNSFLEELKKLLNGGENS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: G6PI_CLONN
Sequence: MYKSLSLDLTKTKPFLNDYEVEQLQPMVSAAHKLLHEKTGAGNDFLGWIDLPVNYDKDEFARIKKSAEKIRNNSEALIVIGIGGSYLGARAAIEMLTHTFGNVASKEARKAPQIFYAGNNISSTYMADLIETVKDMDFSVNVISKSGTTTEPAIAFRIFKDLLEKKYGKEGAKERIFATTDKAKGALRTLADSEGYETFVIPDDVGGRYSVLTAVGLLPIATAGVDIDEMMKGAADAREEYSTDDLSKNTAYRYAAARNALYNKGKNIEMMVNFEPCLHYIGEWWKQLFGESEGKDHKGIFPAAADFSTDLHSMGQYIQEGLRTLVETHLNVEKPRKSVIIEANEDNLDGLNFLAGKDMDYVNNQAFRGTVIAHNEGEVPNMIINIPELTPYYFGYLVYFFEKSCALSGYLLGVNPFNQPGVEAYKKNMFALLGKPGYEDMKAEIEAKLQ
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCA_HALVD
Sequence: MTELGDDPDVEALAAARREEALATNQRRLLVLAGDRDAGIDAAFDAVRGADVPDDEVTFVTAREGFRFHRVEPKRASSLLGTTRTLVVLDAHEEFSANALGRVAGAVDGGGLLVLLTPSLDDWPTRRDSFDERLAVPPFSVADVTGRFRGRLVSTLRDHPGVALVDLDSGTVERDGAYRQGISFDAAPPRVPTEKDRRSPRRAYEDCLTADQSEALAALEALTEPGTAVVVEADRGRGKSSAAGLAAGSLAAEGKDVVVTAPGERNAAEVFARAERLLSELGALRGGGAGDFDIAADRGGRVRYVPPTEAGDAAADADALVVDEAAALPVGLLESFLAAPAVAFCTTVRGYEGAGRGFTVRFRDRLDDADREVTDARLDDPIRYAAGDPVESWTFRALLLDARPPVDQLVADATPETVSYRALSPDDLLADEHLLREAFGLLVLAHYRTEPDDLARLLDAPNLTLRALTHEGRVVSVALLAREGGLDPDTRRQMYDGGRIRGNMLPDVFTSQLRDEGAGVPVGYRVMRIATHHAVRSSGLGSRLLTELRDEFADDADYLGVGFGATPELLSFWRDNGYGTVHLSTTRNDTSGEYSALMTRPLSSAGRDLRDRHANWFLGRVGDVLGDALSDLDADVARAALAAVDSFLSPDLSEYEWRVVVGASYGPGLYTTAPGAFRRLGLAHLTNPERASLTPREERLVVRKVLQTHPWDAVADELDFHSTAGAMRALGDAYEPLVDEYGTDAAREERERFR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_CLOBH
Sequence: MAGDKKFVEDITPMDEDFAQWYTDIVKKAELADYSSIRGCMIIRPNGYGIWENIQKYVDTKLKEYGHENVSMPIFIPENLLQKEKDHVEGFAPEVAWVTHGGDDELAERLCVRPTSETLFCEHYAKIVQSYKDLPKLYNQWCSVVRWEKTTRPFLRTTEFLWQEGHTIHETKEEAESHSLKILNMYSRLCEDMLAMPVVMGKKTDKEKFAGADDTYTIESLMHDGKALQAGTSHYLGQNFSKAFAIQFSDRNGKLDYPHYTTWAVTTRLIGAIIMVHGDNSGLKLPPRIAPTQAVIIPVAQHKEGVLEKAKELKEKLAKVVRVKLDDSDKMPGWKYSEYEMKGIPLRIEIGPKDIEKNQAVLVRRDNREKTIVSLDEIEIKVQEMLDIIHNSMLEEAKKTRDEKTYVATNMEEFEDTIENKPGFIKAMWCGDRACEDKIREVTGATSRCMPFEQEVVSDTCVCCGKKAKNLVYWGRAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_DEHMC
Sequence: MILFRHMEINIIVKPPFKKLVSAQFLKKIASETLKAQAADPSSELGIVITGQEEIKELNCKYRQLDEPTDVLSFYMLEENPENLTAPDDFPTPPDEATHLGEVIISYPQAELQAGAAGHSVNHELAFLLIHGVLHLLGYDHHETAAEAVMKSHQDIAMKHIREILE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_RHOPA
Sequence: MSTSAVTEPVDIVARLQSAGSAEEFFELLGVAYDPKLLNVARLHILRRMGQYLAGEDLEHLPGDEAAARCKAVLERAYADFVASSPLDQRVFKVLKDAVAPKTPKRPAFVPLDALK
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.