PharMolix/UniProtQA huggingface dataset:
Protein: TR10B_HUMAN
Sequence: MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
What is the function of this protein?
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288).  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.  Promotes the activation of NF-kappa-B.  Essential for ER stress-induced apoptosis.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RNB_SHIB3
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGAIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAMRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAP2A_ORYSJ
Sequence: MPRRRGTPLPTILLLLAFVGGACGTEILSKSRLESCSHDSDAGGRLKCDRKLVVDLAVPSGASGGEASLVARVAGVEEENDTPSATKSIRDPPVITVSKSATYALYALTYLDRDVAYRPDEKYVKTHKCEPYAGAKVVGECERLWDEKGNVIKQTEPICCPCGPHRVQSKCGDIWSKLTKGKANTAHCVRFPGDWFHVFGIGAWSLRFSIRVQVKKGSSVWDVVVGPENKTVVSGDNFLRVKVVGDYTGYTSIPSFEDNYLVTPRKGTGSSQPQDLGNEHSKWMILDRVRFTLDGLECDKIGVGYEAYRNQPNFCSAPYGSCLGNQLWNFWEYDKRRIDNSQLPLYIVEGRFQRINQHPNAGAHTFSVGVTEDLNTNLLIELMADDIEYVYQRSPAKIIDIRVPTFEALSQVGIANVTTKNIGKLESSYSLTFKCSSGISPVEEQLYTMKPDEVIARSFELRSTTDQAAMHQCEAILKASDFSELDREGYRFSTAATVYNNGAQIGPTNDHKKGGFWDSIKALWRNLIDFLTGRLCWTKCPRLFDFGCHIQYVCIGWILLLLLIPAAVVFLWLLHQEGLFDPLYDWWGLEPDDDYRARRRHQKGRHHRHHHDHRHRHGHSHGDHHHHYHGGHHQRRRHHHPPAWDVEGHHHDRQQHSHEAGRNHHRGYGEVVAAGAAPLRLDRASRPGQTEVDAVVEYRERRSRHERHGGHGHRDGHYSPSV
What is the function of this protein?
Required for male fertility.  Plays a role in pollen tube guidance and successful gamete attachment.  Essential for the fusion of gametes during double fertilization, where one male gamete fuses with the egg to produce a zygote, and another male gamete fuses with the central cell to produce the endosperm (PubMed:20333238).  Mediates the fusion of cell membranes.  Not required for pollen tube outgrowth (By similarity).
What are the official names of this protein?
Protein HAPLESS 2-A.
What is the protein family that this protein belongs to?
Belongs to the HAP2/GCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single- pass type I membrane protein.
Protein: RS16_TREDE
Sequence: MVKIRLKRLGTKKRPYYRIVVQDVREPRNGKTIDEVGIYHPIETAEKQISFDADKVRNWLGKGAQPTDTVRRLLNKKEFTL
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HOA3_RHOJR
Sequence: MRSSWDIRVTDTSLRDGSHHKRHQFTGEEVRAIVGALDHAGVPVIEVTHGDGLGGSSFNYGFSKVPEQELISIAVDTAKNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVSIQHFGLARDRGLETVGFLMMAHSIAPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEALVQELGSDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQAERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRERL
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 3, HOA 3, 4-hydroxy-2-keto-pentanoic acid aldolase 3, 4-hydroxy-2-oxopentanoate aldolase 3.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: COAA_MYCUA
Sequence: MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVEEVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANPESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSIKRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPI1_STAA8
Sequence: MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: GUF1_COCP7
Sequence: MRGCLQSVRWLTTALRRPAPQLSCLPFQPFASTSRLFSSCASRAATAARKPPSELEQRIAAIPIERFRNFCIVAHVDHGKSTLSDRLLELTGTIEPGSNKQVLDKLDVERERGITVKAQTCTMLYNYKGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAQGLELVPVINKVDLPSADPDRALDQMKSSFELDVEQAVLVSAKTGLNVKQLLPTIVEQIPAPVGDHTKPLRVLLVDSWYDTYKGVILLIRVFDGEIKAGDQVVSFATGKKYIVGEVGIMYPNQTPQTVLRAGQVGYVYFNPGMKQSQEAKIGDTYTKVGSEKLVEPLPGFEEPKAMVFVAAYPVNSDDFPHLEESINQLLLNDRSITVKKESSEALGGGFRLGFLGTLHCSVFQDRLQQEHGANIIITPPSVPCKILWKSGEETVITSPIDFPDDDSSRMKVEEFQEPYVLTTLTFPQEYLGKVIELCEGNRGEQVSLEFFTATQVILKYQLPLAQLVDDFFGKLKGLTKGYASLDYEESGWRKSNIVKLKLLVNKVPVDAVSRVVHTSQVARLGRQWVTKFKEHVDRQMFEIVIQAAVGNKIVARESVKPFRKDVLAKLHASDVTRRRKLLEKQKEGRKRLQAVGNVIIEHKAFQAFLSK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ALF_STRP6
Sequence: MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAPVLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYGDALECIEVGYTSIMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAKAMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQIKEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAVQGAVEERIDVFGSANKA
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: RF1_ENT38
Sequence: MKPSIVAKLEALHERHEEVQALLGDAATIADQDRFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQEELQEAKARAEEMEQQLQVLLLPKDPDDERNAFVEVRAGTGGDEAALFAGDLFRMYSRYAESRRWRVEIMSANEGEHGGYKEVIAKISGEGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEVPEAELPDINPGDLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGSRIRAAEIAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTIYRLDEIMEGKLDSLIEPIVQEYQADQLAALADQD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCND1_HUMAN
Sequence: MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLEDSGSGEEQALCVRNRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSPGGRTSRSTSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSRGSMQELDMLAGLRRSHAPQSRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPDESQPSSPGGGGRAGSTLRNSSLGTPCLFPETVKISSL
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels.  May contribute to I(To) current in heart and I(Sa) current in neurons.  Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
What are the official names of this protein?
Potassium voltage-gated channel subfamily D member 1, Voltage-gated potassium channel subunit Kv4.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.1/KCND1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: BSCL2_BOVIN
Sequence: MVNDPPVPALLWAQEMGHVMAGRARKLLLQFGVFFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCESSTSLLCSFPVANVTLAKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSSLLQMLDTLVFSSLLLFGFAEQKQLLEVELYPEYRENSYVPTTGAIIEIHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGGIWPRQRLSLQVNIRNRKRSRKDIQRKVSAHQPGPQGQEESPQLSPVTEDGESHADPSGTEGQLSEEEKTEQQPLSGEEELEPEASDGSGSWEDAALLTEANLAASGSAPAPETVGSSEPSAGSVRQRPICSSS
What is the function of this protein?
Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity).  In association with LDAF1, defines the sites of LD formation in the ER (By similarity).  Also required for growth and maturation of small nascent LDs into larger mature LDs (By similarity).  Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs (By similarity).  Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts (By similarity).  Binds anionic phospholipids including phosphatidic acid (By similarity).  Plays an important role in the differentiation and development of adipocytes (By similarity).
What are the official names of this protein?
Seipin, Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the seipin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Note=Localizes at endoplasmic reticulum-lipid droplets (ER-LD) contact sites.
Protein: RLMM_YERPA
Sequence: MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKDLPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCYVGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAVDNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQNLAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_PSEPG
Sequence: MTESHDTPITPDGEARPHRRIKSFVMRAGRMTEGQQRGLDQGGPLYILPLADSPVDYDQVFGRSAPRTLEIGFGMGHSLLEMAAAAPEQDFIGVEVHRPGVGALLNGVLTQGLKNLRVYDCDAIEVLNRCVADNSLDRLMLFFPDPWHKARHHKRRIVQLEFAELVRRKLKPGGVFHMATDWEPYAEYMLEVMSAAPGYRNRAADGTYVPRPEERPITKFERRGERLGHGVWDLKFEKVD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TU55_IOTCI
Sequence: LHDPCDNTEDCEDGLECNRNKCLIPYDSDKTCETGWDCVHGVWCSSFPGGSPGCRMDYRCKNEQCEDPATECVDEICGRKEGERCIGPCKAGLTCRNGYCRKPW
What is the function of this protein?
Acts as a neurotoxin by inhibiting an ion channel.
What are the official names of this protein?
Turripeptide OL55-like.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_STRPG
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYRGYYHVLHGLISPMNGMGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: OFOB_SULSP
Sequence: MAAFTPQWNDWCPGCGNFGILNAEQQAIVELGVDTKNVVVVSGIGCSGKIPHFFRTPISGVHTLHGRAIAFATGIKLSNPDLVVIVNGGDGDLLGIGAGHFVAAGRRNVDMVVILHDNGVYGLTKGQASPTLKRGEKPKSLPRPNINDAVNPIALAISSGYTFVARGYAYDVKHLKELIKSAIKHKGLALIDVLQPCPTYNDINTKEWYDKRIYKLDTLPDWDPVVKKPEEVNEKIKRAIDKSLEWGDRIPIGIFYQNELVPSYEERIKANSPAYLDYTPAKQLIEKEGKLTTIIDPLLKEREVD
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase subunit beta, OFOR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_SYNC1
Sequence: MKRKMLKSKIHRATVTGADLHYEGSITIDSELMKQADILPYEAVDIWNVTYGTRFQTYAIEGQPGSGVICINGAAARMVSKGDMVIIASWIDIDADKAAAYEPKLVFVDDKNVPTTQKSENPGQGSLRNAI
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y231_SULNB
Sequence: MRELPKIFGDKSEDLATLFLEQEGFIVIERNYFARKLGEIDIIAQKDEVLHFIEVKSGKADFDPVYNVTPDKLRKVINSAHYYMKSKKIDVSFSVDALIIRGDEVEFIENVTL
What are the official names of this protein?
UPF0102 protein SUN_0231.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SYC_STAAT
Sequence: MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INBP9
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALARPMCVGTTPSAKASILHEVRPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTQNVINAERAPGGPYRLGTSGSCPNVTSRDGFFATMAWAVPRDNKTATNPLTVEVPYICTKGEDQITVWGFHSDNKTQMKNLYGDSNPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHAKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: GLR27_ARATH
Sequence: MKVMNPRKTNNTFMYYFVLFVCGFVLMEGCLGQNQTTEIKVGVVLDLHTSFSKLCLTSINISLSDFYKYHSDYTTRLAIHIRDSMEDVVQASSAALDLIKNEQVSAIIGPRTSMQAEFMIRLADKSQVPTITFSATCPLLTSINSPYFVRATLDDSSQVKAIAAIVKSFGWRNVVAIYVDNEFGEGILPLLTDALQDVQAFVVNRCLIPQEANDDQILKELYKLMTMQTRVFVVHMPPTLGFRFFQKAREIGMMEEGYVWLLTDGVMNLLKSNERGSSLENMQGVLGVRSHIPKSKKLKNFRLRWEKMFPKKGNDEEMNIFALRAYDSITALAMAVEKTNIKSLRYDHPIASGNNKTNLGTLGVSRYGPSLLKALSNVRFNGLAGEFELINGQLESSVFDVINIIGSEERIIGLWRPSNGIVNAKSKNTTSVLGERLGPVIWPGKSKDVPKGWQIPTNGKMLRVGIPVKKGFLEFVDAKIDPISNAMTPTGYCIEIFEAVLKKLPYSVIPKYIAFLSPDENYDEMVYQVYTGAYDAVVGDVTIVANRSLYVDFTLPYTESGVSMMVPLKDNKNTWVFLRPWSLDLWVTTACFFVFIGFIVWILEHRVNTDFRGPPHHQIGTSFWFAFSTMNFAHREKVVSNLARFVVLVWCFVVLVLIQSYTANLTSFFTVKLLQPTVTNWKDLIKFNKNIGYQRGTFVRELLKSQGFDESQLKPFGSAVECDELFSNGTITASFDEVAYIKVILSQNSSKYTMVEPSFKTAGFGFVFPKKSPLTDDVSRAILNVTQGEEMQHIENKWFKKPNNCPDLNTSLSSNHLSLSSFWGLFLIAGIASFLALLIFVANFLYEHKHTLFDDSENSFRGKLKFLVRNFDEKDIKSHMFKENAVHNVSSPITQGSSSPLTDQSTPLPRSPEQYRELELRRVSSISSGELFTTQSEQVEDEESAIIQCEGE
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
What are the official names of this protein?
Glutamate receptor 2.7, Ligand-gated ion channel 2.7.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MINE_BURP0
Sequence: MSILSFLLGEKKKSAAVAKERLQLIIAHERVGGRPPADYLPALQKELVAVISKYVKISNDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SP130_CHICK
Sequence: MSSQQFPRSGAPPPGLGANPPTGPASGTAGLIAPAATTSDESVRDPEVAPRDQHLGPGGPAPPREEKQEPVVVRPYPQVQMLAPHHPVPPGAPVTVAAPPAHLAPAVPLSFSDGLMKPPLKPTMPSRPIAPAPPSTLSAPTKVPGQVTVTMESSIPQAPTIPVATISGQQGHPSNLHHIMATNVQMSIIRSSAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPASQLPNAATAQPAVQHIIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHATESTLSRPTLSIQQHPPSAAISIQRPAQPRDAATRITLPSHPAIGAQKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIASATTAGSVSHTQAPTSTIVTMTMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQSDYTAERSNLIPLSSHRASPNPVAMETRNDNRQSVPVQFQYFLPTYPPSAYPLTAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISAQGIQPAPIGAQGIQPAPIGTQGLHPAAPIGTQGLQPAPISAQQPQADTKTSVVLADGATIVANPISNTFNTASAATTVVQTHSQSASAPAQGSSPRPSILRKKPTTDGLAVRKSLIPPQPPEVASTRVENTMRSTSGSPRPAGAKPKPEIHVSMATPVTVSMEAVSNQGSEQPTIAVPPSSQQPPSAIPTIIAAASPTSQPAAALSTIPGAVPAAPPTSTTIVAAPAPPATMSGALSAVLGPVVPEIKIKEEAEPMDIMRPVSAVPPLTTSTVSPSLALLANNLSMPPSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTALQEGLIPKKKAATDDDLHRINELIQGNMQRCKLVMDQINEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV
What is the function of this protein?
Acts as a transcriptional repressor.  May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).
What are the official names of this protein?
Histone deacetylase complex subunit SAP130, 130 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p130.
What is the protein family that this protein belongs to?
Belongs to the SAP130 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y375_LYSSC
Sequence: MVNIYNDINALEATFRKTPEFEALQAAVEVVKSDEEALNVFKNFRKIQIELQKKQLAGEELLEDELVYAQKASQLVQQNEKISAMLEAEMKLSKVIEEVNRILIKPIQGLYEDIQ
What are the official names of this protein?
UPF0342 protein Bsph_0375.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: C35AB_BACTU
Sequence: MLDTNKVYEISNHANGLYAATYLSLDDSGVSLMNKNDDDIDDYNLKWFLFPIDDDQYIITSYAANNCKVWNVNNDKINVSTYSSTNSIQKWQIKANGSSYVIQSDNGKVLTAGTGQALGLIRLTDESSNNPNQQWNLTSVQTIQLPQKPIIDTKLKDYPKYSPTGNIDNGTSPQLMGWTLVPCIMVNDPNIDKNTQIKTTPYYILKKYQYWQRAVGSNVALRPHEKKSYTYEWGTEIDQKTTIINTLGFQINIDSGMKFDIPEVGGGTDEIKTQLNEELKIEYSHETKIMEKYQEQSEIDNPTDQSMNSIGFLTITSLELYRYNGSEIRIMQIQTSDNDTYNVTSYPNHQQALLLLTNHSYEEVEEITNIPKSTLKKLKKYYF
What is the function of this protein?
Component of a binary insecticidal toxin active on western corn rootworm (WCR, Diabrotica virgifera subsp.  virgifera Le Conte) and probably also on northern corn rootworm (D. barberi).  Both proteins are required for maximal toxicity.  The larval midgut epithelium is probably the primary target (PubMed:11433280, PubMed:11872461).  This protein alone has no activity against southern corn rootworm (Diabrotica undecimpunctata howardi Barber), but it synergizes the toxic effect of its Cry34Ab1 partner (PubMed:12076012).  The 2 proteins individually and together form ion channels; channels made in the presence of the 2 proteins have higher conductance (PubMed:15379574).  Binds to WCR third instar midgut brush border membrane vesicles; binding improves over 10-fold in the presence of Cry34Ab1 (PubMed:23308139).
What are the official names of this protein?
Insecticidal crystal protein Cry35Ab1, 44 kDa insecticidal crystal protein.
What is the protein family that this protein belongs to?
Belongs to the toxin_10 family.