PharMolix/UniProtQA huggingface dataset:
Protein: MSI4_ARATH
Sequence: MESDEAAAVSPQATTPSGGTGASGPKKRGRKPKTKEDSQTPSSQQQSDVKMKESGKKTQQSPSVDEKYSQWKGLVPILYDWLANHNLVWPSLSCRWGPQLEQATYKNRQRLYLSEQTDGSVPNTLVIANCEVVKPRVAAAEHISQFNEEARSPFVKKYKTIIHPGEVNRIRELPQNSKIVATHTDSPDVLIWDVETQPNRHAVLGAANSRPDLILTGHQDNAEFALAMCPTEPFVLSGGKDKSVVLWSIQDHITTIGTDSKSSGSIIKQTGEGTDKNESPTVGPRGVYHGHEDTVEDVAFSPTSAQEFCSVGDDSCLILWDARTGTNPVTKVEKAHDADLHCVDWNPHDDNLILTGSADNTVRLFDRRKLTANGVGSPIYKFEGHKAAVLCVQWSPDKSSVFGSSAEDGLLNIWDYDRVSKKSDRAAKSPAGLFFQHAGHRDKVVDFHWNASDPWTIVSVSDDCETTGGGGTLQIWRMSDLIYRPEEEVVAELEKFKSHVMTCASKP
What is the function of this protein?
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of the flowering autonomous pathway which positively regulates flowering by promoting transcriptional repression of the flowering repressor FLC.  May promote histone deacetylation at the FLC locus leading to the formation of repressive chromatin structures.  Forms a histone deacetylase complex with HDA5, HDA6 and FLD that represses FLC gene expression to control flowering time (PubMed:25922987).  Also negatively regulates cold-responsive genes.  Acts together with PDP1 and MSI5 to regulate the function of the PRC2 complex on FLC (PubMed:29314758).  Required for systemic acquired resistance (SAR) toward pathogenic bacteria (e. g.  Pseudomonas syringae pv tomato DC3000 (avrPto)) (PubMed:32392578).  Together with FLD and MSI4/FVE, contributes to dehydroabietinal-dependent (DA, a diterpenoid tricyclic diterpene) activation of flowering ans SAR (PubMed:32392578).
What are the official names of this protein?
WD-40 repeat-containing protein MSI4, Altered cold-responsive gene 1 protein, Nucleosome remodeling factor complex component 4, Protein MULTICOPY SUPPRESSOR OF IRA1 4, AtMSI4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_PHOV8
Sequence: MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEQLSAVAFTRGPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHFIKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLGQTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHKNDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYIPKFSFTTDNAAMIAITGYYKYLDNDFCTIDKPAYSRVTI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL657_MIMIV
Sequence: MIIYEESASDYYNKNDRLLYGIIEIAESTIVTGSNIISDLENQGSQLQSIHYNLEHIDSDIQIANDKMDHVESCLPSVRKTARKSFKKISKKLFKKKLVSKNSRLDSGVQNSEIQNNSKIQNNSEIQDNFANNFLDNPPDNSRHFSEDNIEKLHNIVCVLEKQANDISNILDEQNNTLEIIHNKIISDEIAIKKITRRIKHTQS
What are the official names of this protein?
Putative t-SNARE coiled-coil homology domain-containing protein L657.
Protein: RRAAH_MYCTU
Sequence: MAISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQDNALLKSVLSQPSAGGVLVIDGAGSLHTALVGDVIAELARSTGWTGLIVHGAVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVTFVPGDIAYSDDDGIIVV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: AT2B4_MOUSE
Sequence: MTNPPGQSVSANTVAESHEGEFGCTLMDLRKLMELRGADAVAQISAHYGGVQEICTRLKTSPIEGLSGNPADLEKRRLVFGKNVIPPKRPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPPGGDNEICGHIASSPEEEEEGETGWIEGAAILASVIIVVLVTAFNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGASEEEDDDDKKKKGKKQGAPENRNKAKTQDGVALEIQPLNSQEGLDSEDKEKKIARIPKKEKSVLQGKLTRLAVQIGKAGLIMSVLTVVILILYFVVDNFVIQRREWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGTHYRQIPQPDVFPPKVLELIVNGISINCAYTSKIQPPEKEGGLPRQVGNKTECGLLGFVTDLKQDYQAVRNEVPEEKLFKVYTFNSVRKSMSTVIRKPEGGFRMFSKGASEIMLRRCDRILNKEGEIKSFRSKDRDNMVRNVIEPMASEGLRTICLAYRDFDGTEPSWDIEGEILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITVRMVTGDNVNTARAIATKCGILTPKDDFLCLEGKEFNSLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGHAVYQLLIVFLLVFAGDTLFDIDSGRKAPLNSPPSQHYTIVFNTFVLMQLFNEINARKIHGEKNVFAGVYRNIIFCTVVLGTFFCQIMIVELGGKPFSCTSLTMEQWMWCLFIGIGELLWGQVISAIPTKSLKFLKEAGHGSDKEDISRDTEGMDEIDLAEMELRRGQILWVRGLNRIQTQIRVVKLFHNNHEVAHKPKNRSSIHTFMTQPEYPADDELSQSFLDIQEGNPELVSKAGTSVLLLDGEAASHDNINNNAVDCHQVQIVASHSDSPLPSLETPV
What is the function of this protein?
Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity).  By regulating sperm cell calcium homeostasis, may play a role in sperm motility (PubMed:15078889).
What are the official names of this protein?
Plasma membrane calcium-transporting ATPase 4, PMCA4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Protein: RR4_CRUWA
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPKAGSDLRNQSRSVKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMALTIPQARQLVNHGHILVNGRIVDIPSYRCKPRDIITVKDEQNSRTLVQNLIDSSAPEELPNHLTLHTFQYEGLVNQIIDRKCVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_THIDA
Sequence: MRKKLVAGNWKMHGSLAENAALLAALKPALQGIEAAVCVPFPYLAQVQTALAGSSLAWGAQNVSEHGKGAFTGEVSASMLLDFGCKYVIVGHSERRSLYGESDALVAAKYMAAQAAGLTPILCVGESLAERESGVTEQVVARQLDAVVAAAGIASLARAVVAYEPVWAIGTGKTASPEQAQAVHAFIRGKLADLDAAVAAGLIIQYGGSVKAANAAELMAQPDIDGGLIGGASLLADEFVAICRAAAK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUN3_MOUSE
Sequence: MLTRSWKIILSTVFISTFLLVGLLNHQWLKETEFPQKPRQLYTVIAEYGSRLYNYQARLRMPKEQQELLKKESQTLENNFREILFLIEQIDVLKALLKDMKDGVHNHSLPVHRDAVQDQATTDVLDEEMSNLVHYVLKKFRGDQIQLADYALKSAGASVIEAGTSESYKNNKAKLYWHGIGFLNYEMPPDMILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVMKKCEGEEIFLGQFIYNKMEATIQTFELQNEASESLLCVKLQILSNWGHPKYTCLYRFRVHGIPSDYT
What is the function of this protein?
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton.  The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning.  May be involved in nuclear remodeling during sperm head formation in spermatogenesis.  A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
What are the official names of this protein?
SUN domain-containing protein 3, Sad1/unc-84 domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus envelope. Nucleus inner membrane. Note=Localized to spermatid nucleus posterior pole lateral regions excluding the implantation fossa during entire sperm head elongation.
Protein: RNPH_PHEZH
Sequence: MRPSDRRPDLLRPVTLETGVNRYAEGSCLASFGHTKVLVTASLEEGVPPFLRGKGQGWVTAEYGMLPRATHTRGRREAAQGKQSGRTQEIQRLIGRSLRAVVDLKALGERQITVDCDVVQADGGTRTAAITGAWVALRLATRYLLEEGVIATDPILDQVAAISCGVFSGTPVLDLDYEEDSNAEADANFVLTGAGDIVEIQATGEKRGFSEAEFEALFALARKGIGELCELQRAATGG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SYGA_SHESW
Sequence: MTTKHDVKTFQGFILTLQEYWAQQGCAIVQPLDMEVGAGTFHPQTFLRSLGPEPMSSAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPSPDNIQELYLGSLQALGIDTQIHDIRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECSPVTGEITYGLERLAMYIQGVDSVYDLVWTDGPMGRITYGDVFHQNEVEQSTYNFEHADVDFMFALFDQCEKMCQHLLSLEKPLPLPAYEQVMKASHAFNLLDARHAISVTERQRYILRVRTMAKAVAESYYQAREALGFPMCK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_AROAE
Sequence: MPTGCSDTYPRLIGDIGGTHARFAVIDSPGSPPTRFRTLCCDDHAGLLEAVQAYLLLERGLAGPRVAAFGIANPVEGDRVRMTNHDWSFSIEQLRIELGLARLVVLNDFTALALSLPRLQAGERRQIGGGNECAGRPVALIGPGTGLGVSGLVRCGNGYAPLEGEGGHVTLAASTPREAELIAVLAARFDHVSAERALSGPGLIALHDAIRQLAGAPPLALEADEISARAMAASCPWCAEALQVFCGMLGSVAGDLALTLGAFGGVYIGGGIVPKLGDFFDRSDFRRRFEQKGRFSEYLARIPCYVILAEYPALLGAATALDNALAGETGT
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SYNS3
Sequence: MAKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMSRLNSVTTGSIYQSVINKERRGSYNGGTVQVIPHITGEIRDRIHRVASNSNADVVITEIGGTVGDIESLPFLEAIREFRGDVGRQDLAYIHVTLLPFIGTSGELKTKPTQHSVKELRSIGIQPDLLVCRSDRDINDELKRKIGGFCGVPQRAVIPSLDADSIYAVPLTLEDEGLCREVLDVLDLEDHDSDMVDWAQLVHKLRNPGPAVKVALVGKYVQLNDAYLSVVEALRHACLAQDASLDLHWVCAEEIENQGADVLLKGMDAVVVPGGFGNRGVDGKVAAIRWAREQRVPFLGLCLGMQCAVIEWARNLAGLTDATSAELEPGTTHPVIHLLPEQQDVVDLGGTMRLGVYPCRVSAGSLASRLYGEEVVYERHRHRFEFNNAYRNLFLESGYEISGSSPDGRLVELIELPEHPFFTACQYHPEFLSRPGRPHPLFRGLIEAAQQRLPCSPSEAMRQQNNSAAGSSHPSLQP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MURC_VIBC3
Sequence: MTIKHTQDLAQIRAMVPEMRRVKAIHFIGIGGAGMSGIAEVLLNEGYQISGSDLAANAVTDRLADKGATIFIGHEAHNVAHASVVVVSTAINEQNPEIQAAREKRIPIVRRAEMLAELMRFRHGIAVAGTHGKTTTTALVTQIYSEAGLDPTFVNGGLVKSAGTNARLGSSRILIAEADESDASFLHLQPMVTIVTNIEADHMDTYGGDFENLKQTFIDFLHNLPFYGQAILCIDDPVIRELIPRVSRQVITYGFSEDADVRIENYRQNGQQGQFTVVRKGKANLDITLNIPGRHNALNAAAAIAVATEDDIRDEAILRAMANTQGTGRRFDHLGEFETGNGVAMLVDDYGHHPTEVDVTIKAARNGWAEKRLVMIFQPHRYTRTRDLYDDFANVLEQVDVLLMLDVYAAGEKPIAGADGRSLCRTIRSRGKIDPIFVPDSQTLPSVLANILQDGDLVLTQGAGDVGKVARHLAALELNIGRMQQI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_AZOC5
Sequence: MAEPTSTLSTATPAAPRISFVSLGCPKALVDSERIVTRLRAEGYELTRNHDGADLVIVNTCGFLDSAKAESLSAIGEALAENGKVVVTGCMGAEPEQIRAVHPSVLAITGPQQYESVLDAVHQAVPPKHDPFLDLVPEQGVKLTPRHYAYLKISEGCNNRCTFCIIPKLRGDLVSRPLNEVMREAEKLVAAGVKELLVISQDTSAYGVDLKYAESRWKDRDWATRFFDLADALGDLGAWVRLHYVYPYPHVDRVMELMASGKVLPYLDIPFQHASPTVLRRMKRPAAQEKTLARVLAWRDAVPDITLRSTFIVGFPGETEEEFQELLDFLDEAQLDRVGCFKFEPVAGAPANALENPVPDEVKAERYDRFMLKQQAISARRLKRKVGTRQQVIIDSVTPGGAIGRTKGDAPEIDGSVKIASRRPLRVGEIATVKIEAADAYDLIGSAVGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASF1_ASHGO
Sequence: MSIVSLLGVKVVNNPAKFTDPYEFEITFECLEPLKHDLEWKLTYVGSSRSLEHDQELDSILVGPIPVGVNKFLFTADPPSAELIPASELVSVTVILLSCSYDGREFVRVGYYVNNEYDTEELRNDPPQKVQVDHVVRNILAEKPRVTRFNIVWDNEAEDEYPPEQPGVDDEEVDDEDEDEDEDEEGADEEGADEEGASDGPDAKKRKVQTEDEEDDEAEEIDLEAEEEEDEDEEDEDGDEAEEVDEEEEDDDGEPVGASEGGADTVPTPQDTTESK
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRPL1_HUMAN
Sequence: MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTALATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQRPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW
What is the function of this protein?
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:12783849).  May activate the MAP kinase JNK (PubMed:15123616).  Plays a role in neurite outgrowth (By similarity).  During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
What are the official names of this protein?
Interleukin-1 receptor accessory protein-like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, Oligophrenin-4, Three immunoglobulin domain-containing IL-1 receptor-related 2, TIGIRR-2, X-linked interleukin-1 receptor accessory protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Note=May localize to the cell body and growth cones of dendrite-like processes.
Protein: TRUB_MYCPU
Sequence: MFYLIYKEKGISSFKAIKDFAWQNNIKKIGHSGTLDPEATGLLLLASDEDTKLLDYVDKKFKSYRATMILGLQSQSFDSQGKIINSSNLKVDNLTIEKTIKNFVGPFVQIPPIFSAKKINGKRAYEYARQGSEISMKAQEVFVKSIEIEKIDFPKVIFKAKVSRGTYIRSLINQIGLELKTYALMDDLERIELSGLSKNDLGVVSDLDIIDLEVLSLEKHEILTLAKGQKFSKDLADGKYAFIYKNTKKILGICKIESKIIAPIKIFNKKIEKSLKKDEKNE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FKB35_PLAF7
Sequence: MTTEQEFEKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPFKFHLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGESIPGNSVLLFEIELLSFREAKKSIYDYTDEEKVQSAFDIKEEGNEFFKKNEINEAIVKYKEALDFFIHTEEWDDQILLDKKKNIEISCNLNLATCYNKNKDYPKAIDHASKVLKIDKNNVKALYKLGVANMYFGFLEEAKENLYKAASLNPNNLDIRNSYELCVNKLKEARKKDKLTFGGMFDKGPLYEEKKNSAN
What is the function of this protein?
Has peptidylprolyl isomerase (PPIase) and co-chaperone activities (PubMed:15664653, PubMed:15850699).  Assists protein folding by catalyzing the peptidyl conversion of cis and trans rotamers of the prolyl amide bond of protein substrates (PubMed:15664653, PubMed:15850699, PubMed:23974147).  Inhibits calcineurin phosphatase activity in vitro (PubMed:15850699, PubMed:17289400, PubMed:23974147).  Plays an essential role in merozoite egress from host erythrocytes (PubMed:15664653, PubMed:23974147).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP35, PfFKBP35.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=During the asexual blood stage, predominantly localizes to the cytoplasm of ring stage parasites and then translocates to the nucleus during the differentiation into trophozoites and schizonts.
Protein: CINAL_SYNFM
Sequence: MDERPPEISGSLLTIGDEILLGDILNGNARHIALELRNRGFRLDRMITVGDREEDIVSSLVLCLADARFIIVTGGLGPTDDDRTNAAVSRAFDRPLVADEAYVGRLKERLAERGQAWSNEVAKMAELPAGAVKIGLDMAGFFIDHGNVPCYFLPGVPGEMKFLLAEVVIPDLARRFPLRGAYLKEVVRVQGMVESEVNRRLRDLDCRRIGVEIGYLPQGSENWVTLFAVAASEEECRTRIEKVREEVVARLGEKHISGRNDECLEKVVGERLRERGWRMAAAESCTGGLLSTRLTSIAGSSDYFDRAFITYSNQAKQDHLGVSEEMLRVHGAVSEPVALAMAEGACRGARVEVALGITGIAGPAGGSAEKPVGTVCIACVTPKEKRVEKHRFEGVRESIRQSAAQAALLLLWRVLTDDSNLHCR
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: FGD_MYCLB
Sequence: MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRVDFDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG
What is the function of this protein?
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.  Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: RECR_BART1
Sequence: MSKYIAGPEIERLIQILARLPGLGPRSARRAALHLIKKKETLLEPLGAAVQAAIEKVGICSVCGNVDTIDPCSICTDSRRDDTTIIVVEDIADLWALERAKTLAARYHVLGGRLSPLDGIGPDELNIATLIQRVVQNPITEIILAVNATVEGQTTAHYITDQLSNFPVKITRLAHGVPVGGELDYLDDGTLAAAVQARTNL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GSTP1_BOVIN
Sequence: MPPYTIVYFPVQGRCEAMRMLLADQGQSWKEEVVAMQSWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKEDYVKALPQHLKPFETLLSQNKGGQAFIVGDQISFADYNLLDLLRIHQVLAPSCLDSFPLLSAYVARLNSRPKLKAFLASPEHMNRPINGNGKQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2).  Participates in the formation of novel hepoxilin regioisomers.  Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
What are the official names of this protein?
Glutathione S-transferase P, GST class-pi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Pi family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Protein: FXI1C_XENTR
Sequence: MNSIHLPSHQRTSAPGLHQHRPKGAQEASEMAVYCDNFSMYHQQNLHSSQRAPNYGIGDYAPPTNPYLWLGGPGVSNSPSNSSSFCGTDLSWLSVASQEELLKVVRPPYSYSALIAMAIQNAPEKKLTLSQIYQYVADNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSDSSSAEAVTVKGEEGRPALGGKGGESPLMLTPSSPELEAASDGRKSTSPSGITSSPCLNNFFSSMTSLDTTSVNRQMSMGLVNELSQRNITGLGSFTSGSVAEPSVDLQDNSLHLNRPSYYSTLSSTHQNNQFNSHFYNTFSVNSLIYAREGSEV
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Forkhead box protein I1c, FoxI1c.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEU3_SYNE7
Sequence: MTRSYRITLLPGDGIGPEIMAVTVDILRAIGRQFDLNFEFEEALIGGSAIDATGEPLPEATLATCRNSDAVLLAAIGGYKWDSLPRSQRPETGLLGLRAGLGLFANLRPAAILPQLVDASSLKREVIEGVDLMVVRELTGGIYFGEPKGCFADEQGRQRAFNTMVYREDEIDRIGRVAFDIARKRGKRLCSVDKANVLEVSQLWRDRMTLLGSDYADVELSHLYVDNAAMQLVRWPKQFDTIVTGNLFGDILSDIAAMLTGSIGMLPSASLGAEGPGVFEPVHGSAPDIAGQDKANPLAQVLSAAMMLRYGLDEPEAAARIEAAVNQVLDQGYRTGDLYSEGMTLVGCKGMGDALLAALESPVSA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_CHLTE
Sequence: MKNYEIAAMDKKELLSKIKELENRLADLNFYQAIEPAQNPMVFRNLKRDIARMKTRLTQIDRQEKSNA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL9_STRZP
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAVGELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAEELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.