PharMolix/UniProtQA huggingface dataset:
Protein: Y1469_CLOBL
Sequence: MPRPTKFRRVEFFPENNYFVPWGKPKCEIHEVVLKVEELEAMRLKDIEELNQEQCAEKMEISRQTFQNIIDSARKKVAIALTEGKAIKISGGHYTTKLCKLKCIDCEEIYEINYEQDRHLCPNCGSEKVICNKKADFCRRWCKGQNRKEQYEESKNK
What are the official names of this protein?
UPF0251 protein CLI_1469.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: DNAK_HERAR
Sequence: MGKIIGIDLGTTNSCVAIMEGGKPKVIENSEGARTTPSVIAYQEDGEILVGAPAKRQAVTNPKNTLYAVKRLIGRKFDEKEVQKDIGMMPYQIVKADNGDAWISVRDKKLAPPQISAETLRKMKKTAEDYLGEEVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAFGLDKTGKGDRKIAVYDLGGGTFDISIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRVIDYIIDEFKKINGLDLSKDAIALQRIKASAERAKIELSSSQQTEINEPYIAMANGAPVHLTMKITRAKLESLVEELISKTLAPLSIAIKDAGVKVSDIDDIILVGGMTRMPKVQEKVKEFFGKEPRKDVNPDEAVAVGAAIQGSVLSGDRKDLLLLDVTPLSLGIETLGGVMTKMIQKNTTIPTKFSQVFSTADDNQPAVTIKVFQGEREMAVGNKALGEFNLEGIPPSARGTPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLTEEEIQKMVQDAEANAEEDKRLKEVAEAHNHGDALVHSTRKSLTEYGDKLEAGEKEKIEAAIKDLEEALKGSDKAAIDEKSAALSAAAQKLGEKMYADMQAQQAAGAAAGDAHAAGADGQADAKAQHDDVVDADFKEVKDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: VL1_HPV23
Sequence: MTLWLPASGKIYLPPTPPVARVQSTDEYVERTDIYYHATSDRLLTVGHPYFDVRSPDGSKIDVPKVSGNQFRAFRVTFPDPNKFALADMTIYDPDKYRLVWACAGLEIGRGQPLGVGSTGHPLFNKLRDAENSSERQEGTVDDRRNISFDPKQVQMFIIGCTPCLGEYWDTAPVCKDAGSQLGLCPPLELKNSVIEDGDMFDIGFGNINNKTLSFNRSDVSLDLVNEVCKYPDFLTMSNDVYGDACFFCARREQCYARHYFVRGGVVGDAIPDGAVQQDHKYYLPADQQNTLENSLYFPTVSGSLVTSDSQLFNRPFWLKRAQGHNNGILWNNQMFVTVADNTRNTNFSISVTNDSSLEKYDATKIREFTRHVEEYQLSFILQLCRIPLKAEVLTQINAMNSDILENWQLGFVPTPDNAVHDTYRYLASKATKCPDAVPDTQKEDPFGKYSFWNVDMTEKLSLDLDQYPLGRKFLFQIGVQRVRSGTKRPATRKVTKTVKRKKVQL
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ORN_HAEDU
Sequence: MNKLANQHLIWIDLEMTGLDPNQDRIIEIATIVTDKDLNILAKGPVLAVHQPNTLLSKMNEWCIKTHTANGLIERVKQSKLTERAAELQTLDFLKQWVMKGSSPICGNSVAQDKRFLYQYMPDLADYFHYRHLDVSTLKELARRWKPEILQQFSKKNSHLALDDIRESIEELKFYREHFIKLA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_GEOUR
Sequence: MERTFAIIKPDAVERNITGKVLDKIEGAGFKIVGMKKIHLTKNEAEGFYYVHKERPFFNDLCTFMSRNPVVVLALEKENAIAAWRELMGATNPANAEAGTIRKDFGVSIEENTVHGSDSPESAAFEIPYFFSQLELV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_PROMM
Sequence: MLLGVILSIPRLVLFLPGVPVTSTLPSQPKDADLAVSARPSAQGRFGRYGGQYVPETLMPALAELEQAAALAWKDPAFTAELDRLLRSYVGRATPLYEAERLTAHYCRSDGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVVYMGAEDMRRQALNVFRMRLLGATVQPVTAGTATLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMLVRDFHAVIGQEARQQCAEAFGRLPDVLLACVGGGSNAMGLFHPFVQDRSVRMIGVEAAGDGVETGRHAATITEGRVGVLHGAMSLLLQDDEGQVQEAHSISAGLDYPGVGPEHSYLCEIGRAEYAAVSDQQALDALRLVSELEGIIPALETAHAFAWLETLCPTLAAGTEVVINCSGRGDKDVNTVAEKLGNQL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: 068R_FRG3G
Sequence: MWIHFPVRNYIHLSHTILHYPCPDNAGHVCGHRNVSRNGLKDGLGVGVVSGGVDRTVYDRDTYPHPIKESDEDLGGGGVGSRERVGPVGGDHCHG
What are the official names of this protein?
Putative uncharacterized protein 068R.
Protein: SES1B_XENLA
Sequence: MDATVILPILKKKLAFLSGGKDRRSGLILTIPLCSDQTSMDELSVTLDYLLSIPSEKCKARGFTVIVDGRKSQWNVVKTVVLMLQNVVPAEVSLVCVVKPDEFWDKKVTHFCFWKEKDRLGFEVILVSGNKLTRYIEPNQLTEEFGGSLTYDHMDWLNKRLVFEKFTKESTSLLDELAVINNGSDKGSQNEKERSVDFNYLPSVDPETVLQTGHELLSELQQRRFNGSDGGVSWSPMDDELLAQPQVMKLLDSLREQYTRYQEVCRQRSKRTQLDEIQQKVMQVVSWLEGPGSEQLRTQWGIGDSIRASQALQQKHEEIESQHSEWFAVYVELNQQIAALLNAGDEEDLVELKTLQQRLSDVCYRQASQLEFRQNLLQIALEFHSVSQDLSQQLDGLLGMLCADVAPTDGATIQQTLKLLEEKLKSVDTGLQGLREKGQGLLDQITNQASWAYGKDVSTENKDNVDHIQGVMEDMQLRKQRCEDMVDVRRLKMLQMVQLFKCEEDAAQAVDWLNELLDALLKTHIRLGDDSQETKILLEKHRKFVDVAQSTYDYGRQLLQATVVLCQSLRCTSRSSGDTLPKLNRVWKQFTITSEERVQRLEMALAFHSNAEKILQECPDLGETVMDFEQFDEVEAVGKSLLDRLTVPD
What is the function of this protein?
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels trpc4 and trpc5.  Binds phospholipids (By similarity).
What are the official names of this protein?
SEC14 domain and spectrin repeat-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the SOLO family.
Protein: MNME_AYWBP
Sequence: MFFDTIAAISTPLGTGGVSVIRVSGNNSITEINKIFKGKNLIKAKTHTITHGFILNKDQTILDEVLISVFKTPNSFTGENVVEINAHGGILITQMVLERILSLDIRLAFPGEFSQRAYLNGKMDLIQAESIMDLIHATNENAIKIANSGLQKYTSQLVTSLRDQILNLIAQIEVNIDYPEYDDIPQITQQKIALEVQSLIKQLENILSHSHKNRYLKEGIKTLIIGRPNVGKSSLLNAFLNENKAIVSDISGTTRDFVEAYFNCRGFTLHLIDTAGIRKTDDPIEKIGILRTEKMLLQAELILLVLDQSNYLQEEDIQLLQLTQNYPRIIIGNKVDLKSDKLISSLCDYSSQLTPQEIISVSSLDKTGFFELQQTILKKFQLNDIKPKDFNYFSNARHINQIQIALRSFQDLQQALLQSMPIDIYSIDLTKAYQALGQIIGENQENSLIKELFSKFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_PEDPA
Sequence: MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTAEQARSLGINVKSVDEVDHIDLTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIVDESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFRKNDAGEYVLTDSKNYVIDLHLGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MURA_XANC5
Sequence: MAKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSILVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKGGRYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRIETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATIQRTA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_STAHJ
Sequence: MSSKAWGGRFQQQPEDWVDEFNASIDFDQTLLDEDVQGSIAHATMLANQNIISQDDKDAIINGLKEIQQDFHNGKLAFKKSLEDIHLNIEHELIQRVGDAGGKLHTGRSRNDQVATDLHLYVKKEVLEIQDLIRSFQTSILKLAQSHVDTIMPGYTHLQRAQPISFAHHVMTYFWMLERDYSRFVDSMKRIDISPLGAAALSGTTHPIDRHETQQLLEFSSVYENSLDAVSDRDYIIETLHNISLTMIHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRATGHLMSMLVTLKGLPLAYNKDLQEDKEGLFDSVRTIKGSLRIFEGMLDTMTVNTDRLNETVHQDFSNATELADYLVAKDVPFRKAHEIVGKIVFECIQQGIYLLDVPLERYKELNSNIDQDVYDYLKPENCLSRRKSYGSTGQDAVRHQLKVAEKLLNND
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2128_SHEDO
Sequence: MKKHLLASLLGASLLLPTAVNAADYVIDTKGAHASIQFSVSHLGYSFVVGRFNEFDGKFSFDAAKVSDGKVEVNINTNSVDSNHAERDKHLRSDDFLNTAKFPAAKFVSTSVADKGNGDLWITGDLSLNGVTKPVTIKAHTVGEGQDPWGGYRAGFVGSTEFTMKDFGIKMDLGPASANVKLDLVVEGIKQ
What are the official names of this protein?
UPF0312 protein Sden_2128.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPXK_POLNS
Sequence: MSFSFFRKAPKFWERRGPTSLLLWPLSWIYGLVLHARKLIQDTGFVKPKPAPVPIIIVGNIRVGGTGKTPIVIALAERLQQLGWNPGIISRGYGGKGSSAQTSPLQVKSNSDPTLVGDEPVLIARRTHDQFPIWVFPKRQQSIRELLKHSPNVNVIISDDGLQHSGLARWPAREGGRDIELVVRDERGEGNRFLLPAGPLREPATRERDATLFTGKIKSDDHQIGLQDEYFLGRRAFSLLSNLGKPYQLNNPANTQTLTQIADSYLPNKITTVAALGNPQRFFDDLLKNGIAGKTISLPDHATYTPEFFTKLNAQCILITEKDAVKCSAIMDECIWVVPMSLALSDNLAEWLQSILQRPDPYRYTL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL32_STRZJ
Sequence: MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSLKGYYKGRKITKAASAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MDH_ACIBT
Sequence: MKQPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLEVPVEKAQQALKGVMMELDDCAFPLLAGMIGTDDPKVAFKDADYALLVGSRPRGPGMERADLLKVNGEIFIGQGQALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALTQVAQKAGVAVADIEKLTVWGNHSPTMYADYRFATANGESLKDKINDPAWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGEYKIVQGLEIDEFSRERINFTLNELEEERAAIADMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: PSAJ_NASOF
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1419_SYNY3
Sequence: MNRLSIIFPNLVMANATLPPNLAKIVERFQRHTDPKKRYEQLLWYGKKLEPMMEEGKIAANKVQGCVSQVYITADLEDGKVMYQGDSDAQLVKGLVALLIQGLNGLTPTEIVELTPDFIEATGLQVSLTPSRANGFYNIFKMMQTKAIAFQLGQSYGEG
What are the official names of this protein?
Uncharacterized SufE-like protein slr1419.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
Protein: ERA_MARN8
Sequence: MTDITRPENPESRCGFVAIVGRPNVGKSTLLNHILGQKLSITSRKPQTTRHQVLGIKTEGPVQAIYVDTPGMHEDEPRALNRYMNKAAASALIDVDVVVFVVDQLAWTSADEMVLEKLKRVKCPVILAVNKVDKLEKRELLLPHLEALSKKRDFAEIIPLSALKETNLEPLESAVGRFLPESVHFYPDDQITDRSERFMAAEMVREKITRQLGAELPYSVAVEIEEFKHQGNTLHVSALILVEREGQKKIIIGDKGERLRSIGQEARVDMERMFGSKVMLRLWVKVKRGWADSDRALKSLGMSDF
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: IXTPA_LEUMM
Sequence: MKLIIASNNAHKITEIEALLASISIDLPVVSLQEIGDVPEIVEDGTTFEENAVKKVETIAKVAPNDYILADDSGMSVDALNGEPGVYSARYAGDHDDQANIDKVLQKLAKVPNEQRTAHFNSVIALHSPKGSNLIVNGQVDGYITESERGQDGFGYDPIFFVPSMNKTFAEMSASEKNTISHRGLALQELGKKLPVWLKGE
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ZN652_HUMAN
Sequence: MSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSVVNTATTPTPPINMNPVSTLPPRPIPHPFSHLHIHPHPHHPHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDNFLRHLAEKNSSAQHH
What is the function of this protein?
Functions as a transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 652.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMPA_SODGM
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISTLLRRGELEGKVGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVINKTINTLNDTGSMEAVCFLTELHVKGRNTYWKVRQAVETAKETLYTFDQLKSNKIEPRRPLRKMVFNVPTRRELTSGERAISHGLAIAAGIKAAKDLGNMPPNICNPAYLASQARQLADGYGKTTTTRVIGEQQMKELGMNAYLAVGQGSANESLMSVIEYKGSPDADARPIVLVGKGLTFDAGGISIKPADSMDEMKYDMCGAATVYGVMRMAMELNLPLNIVGVLAGCENMVDGRAFRPGDVLTTLSGQTVEVLNTDAEGRLVLCDALTYVERFEPEVVIDVATLTGACVIALGHHLTGLVSNHNPLAHELIGAAEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFARKYNWAHLDIAGTAWRSGKAKGATGRPVAMLSQFLLNRTGLNGDE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGP_SALHS
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ACSA_METSB
Sequence: MSDKVYPVTAEWSKSAYVDAAKYKSMYESSVSEPDKFWGEHGKRIDWVKPYTKVKNTSFDPHNVSIKWFEDGVTNVSTNCIDRHLATLGDQTAIIWEGDDPNESKHITYKQLHEEVCRLANVLKSYGISKGDTVTIYLPMIPEAAYAMLACARIGAIHSIVFGGFSADSLGGRIEGCKSKLIITADEGYRGGRKVPLKVNADAAIKKVDGIVETMIVVRRTGGKVAWTEGRDVWYDEALAKASPDCPAAEMNAEDPLFILFTSGSTGAPKGVVHSTGGYLVWASMTHQYVFDYRPGEVYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPSYPTISRFWDVVDKHQVNIFYTAPTAIRSLMGAGDGPVKATSRKTLRVLGSVGEPINPEAWEWYYRVVGEERCPIVDTWWQTETGGILISPLPGATALKPGSATQPFFGVQPQVVDAAGEVLEGPCSGNLVIADSWPAQMRTLFNDHERFVQAYFSAYPGKYFTGDGCRRDEDGYYWITGRVDDVINVSGHRLGTAEVESSLVAHIKVAEAAVVGYPHDLKGQGIYAYVTLMTGIEPSEELRKELVSWVRKDIGPIASPDIVHFAPGLPKTRSGKIMRRILRKIAEKEFSALGDTSTLADPSVVDDLIRERAN
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ZNT7_BOVIN
Sequence: MLPLSIKDDEYKPPKFNLFRKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQTHGHGDHCHSHELKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAMLIVISVIPLLRESVGILMQRTPPLLENTLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM
What is the function of this protein?
Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway.  By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases.
What are the official names of this protein?
Zinc transporter 7, Solute carrier family 30 member 7.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: KAD_NEIPH
Sequence: FITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSKLEGEHAPK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXPR2_THRPR
Sequence: YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
What is the function of this protein?
Gating-modifier toxin that targets voltage-gated sodium channels with a selective activity on Nav1. 7/SCN9A (IC(50)=1-1. 5 nM) (PubMed:25026046, PubMed:31234412).  It inhibits both activation and inactivation (PubMed:20855463).  For inhibition of activation, it is 100-fold more selective for Nav1. 7/SCN9A (IC(50)=0. 26-3) than for other sodium channels (Nav1. 2/SCN2A (IC(50)=40-540 nM), Nav1. 3/SCN3A (IC(50)=102 nM), Nav1. 4/SCN4A (IC(50)=30-39 nM), Nav1. 5/SCN5A (IC(50)=19-90 nM), Nav1. 6/SCN8A (IC(50)=26 nM), and Nav1. 8/SCN10A (IC(50)=146 nM)) (PubMed:12475222, PubMed:17087985, PubMed:18156314, PubMed:18728100, PubMed:20855463, PubMed:25658507, PubMed:27311819, PubMed:30661758).  For inhibition of inactivation, it is 20-fold more potent in inhibiting inactivation on Nav1. 7/SCN9A (IC(50)=250 nM) than other channels (about 4. 6 uM for all channels) (PubMed:20855463).  It also weakly inhibits Cav1. 2/CACNA1C and Cav3. 2/CACNA1H (29% block at 1 uM) (PubMed:17087985, PubMed:20600227, PubMed:24886690).  It inhibits Nav1. 7/SCN9A activation by interacting with DII and impairs Nav1. 7/SCN9A inactivation by interacting with DIV (PubMed:20855463).  It docks on top of the DII S3 helix Nav1. 7/SCN9A (PubMed:30661758, PubMed:30765606).  It is about 60-fold less active on Nav1. 7/SCN9A at depolarized potential (0 mV; IC(50)=15 nM), compared to -120 mV potential (IC(50)=0. 26 nM) (PubMed:30661758).  This toxin binds to lipid membrane (PubMed:15632158, PubMed:27311819).  This ability correlates with hNav1. 7/SCN9A inhibition, showing that membrane binding is the first step in the inhibitory mechanism of this toxin (PubMed:27311819).  It inhibits Nav1. 2/SCN2A less potently when it is coexpressed with SCN2B or SCN4B than when it is expressed alone, showing that beta subunits (SCN2B and SCN4B) have a protective effect (PubMed:24297919, PubMed:26894959).
What are the official names of this protein?
Beta/omega-theraphotoxin-Tp2a, Beta/omega-TRTX-Tp2a, Protoxin-2, ProTx-2, ProTx2, Protoxin-II, PT-II, ProTx-II.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE_STRP6
Sequence: MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIEDTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKAYKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAVNESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMPEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKHADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEAEKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPNTIYLLGRDKSIEHIKNML
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_SHEON
Sequence: MNHKVLLINGPNLNLLGRREPSVYGHQTLADIVAQLNEQAQAAGVQLEHIQSNAEFELINAIHATDAQMIIINPAAFTHTSVALRDALLGVDIPFYEVHLSNVHAREPFRHHSYLSDKAIGVICGFGAQGYEFALTAAIKRLKSAT
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.