PharMolix/UniProtQA huggingface dataset:
Protein: PYRI_METHJ
Sequence: MTNEEPKRTLVISTIENGTVIDHIKAGEALTVLRILGITGSTRECVSVATNVSSKAQEKKDVVKIEKRELKAQEVDRIALVAPNATINIIRNFRVIEKKGVIIPPVLIGVLRCPNPCCITNTNEPVMSRFEMHGKKAVCSYCDAVISSDISSHII
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RSMA_MYXXD
Sequence: MESPRDILKRHGLRAKYSWGQNFLGDEDALEAIADALNLRADEPVVELGPGLGHLTRFLAATGARVTAVERDRDMVMVLEKEAIPGVRVVSGNAATVDFAQVAGAPDVAVAGNLPYHLTSPILFRVLEQRAHVSRAVFTLQKEVVERLAAEPGNRDYGLLTVLLGMHYDAENVLTLEAWRFHPPPKVDSAVLRLTRRKSPRAPIIDEARFTRVVKASFAHRRKTLINSIKSDPTLGTTETLIAALEAAGVDPQRRAETLTPEEFAAIERALGPLTPATSTPAE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPPPS_MYCTU
Sequence: MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVTVAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMRETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPGTDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVLAQYAAQARHELALLPDVPGRRALAALVDYTVSRHG
What is the function of this protein?
Catalyzes the sequential condensations of isopentenyl pyrophosphate (IPP) with geranyl diphosphate (GPP) to yield (2E,6E)-farnesyl diphosphate (E,E-FPP), with E,E-FPP to yield geranylgeranyl diphosphate (GGPP) and with GGPP to yield nonaprenyl diphosphate (PubMed:23091471, PubMed:30301210, PubMed:32495977).  May also have weak activity with dimethylallyl diphosphate (DMAPP) (PubMed:23091471).
What are the official names of this protein?
Nonaprenyl diphosphate synthase, (2E,6E)-farnesyl diphosphate synthase, E,E-FPP synthase, FPP synthase, Geranylgeranyl diphosphate synthase, GGPP synthase, GGPS.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: EFTS_GEOMG
Sequence: MSITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRKKGLAAASKKAGRVASEGAVGSYIHAGGKIGVLVEVNCETDFVARNENFQAFVKDIAMHIAAAAPQYVRREEVTADVVEREKEIYRAKARETGKPENIIEKIIEGQVNKFYADICLLEQQYVKDSDKTVQQFLNETIASIGENISIRRFVRYALGEGLAKKETDFAAEVAAAAGL
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMY_METTP
Sequence: MRDFVIVGHIAKTTPDFSLEDLPGTSGRIDVLCRCVNSAFMLSHGIRRDVRCHLILMGGPEPKILRFDGSRLRHLNPDERSTAALIKRALSIDASPSWRESTPGIYIRKGDLRSLLESLRDEGQRLYYLREDGAPLSESVSDGVFVLGDHTGMTGDEEHLLDSMGAETVSIGPLSLHADHCIVIVNWMCDNAALRR
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S22AO_HUMAN
Sequence: MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVSDNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLTLNHMGRRISQILFTFPVGLFILVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVILLLPETRDLPLPNTIQDVENDRKDSRNIKQEDTCMKVTQF
What is the function of this protein?
Lack of transporter activity.
What are the official names of this protein?
Steroid transmembrane transporter SLC22A24, Solute carrier family 22 member 24.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Multi-pass membrane protein.
Protein: MAD58_ORYSJ
Sequence: MHIYKEQEAEPSTGLMMPEPAPVASPGSGGSGGSGSVGAEKIGSRGKIEIKRIENTTNRQVTFCKRRSGLLKKAYELSVLCDAEVALVVFSSRGRLYEYSNNSVKETIERYKKANSDTSNASTVAEINAQHYQQEAAKLKQQITNLQNSNRTLVGDNITTMNHRELKQLEGRLDKGLGKIRARKNELLCAEIEYMQRRETELQNDNMYLKSKVAESERGLQTVNMMGSASTSEYVQNMIHYDPRNFLQFNIMHQPQYYPEQEDRKAFMSDER
What is the function of this protein?
Probable transcription factor involved in the development of floral organs.  Acts as a C-class protein in association with MADS3.  Involved in the control of lodicule number (whorl 2), stamen specification (whorl 3), floral meristem determinacy and regulation of the carpel morphogenesis (whorl 4).  Plays a more predominant role in floral meristem determinacy than MADS3.
What are the official names of this protein?
MADS-box transcription factor 58, OsMADS58.
What are the subcellular locations of this protein?
Nucleus.
Protein: LYAM2_RABIT
Sequence: MVASWLLSTLTFALVLLIKETSTWTYHFSAENMTYDEASAYCQQNYTHLVAIQNKEEIDYLNSILDYSPSYYWIGIRKVNNVWIWVGTHKPLTEGAKNWAPGEPNNKQNNEDCVEIYIKRPKDTGMWNDERCSKKKLALCYTAACTEASCSGHGECIETINNYSCKCYPGFSGLKCEQVVTCEAQVQPQHGSLNCTHPLGNFSYNSSCSVSCERGYLPSSTETTWCTSSGEWSAPPATCKVVECDTMGKPANGDVKCSPSQGSAPWNTTCTFDCEEGFTLLGARSLQCTSSGSWDNEKPTCKAVSCDTIHHPQNGSVSCSNSSEGKFTFRSSCNFTCEENFLLRGPAQVECTAQGQWTQQAPVCEAVKCDPVHTLEDGFVKCTHPHTGEFTYKSSCTFNCREGFELHGSAQLECTSQGQWAQELPSCQVVQCPSLAVLGKTNVSCSGEPVFGTVCNFACPEGWTLNGSAALMCGAEGQWSGMLPTCEEPIASNVPLAVGLSVSGTSFLTLTSFLLWFLKYFRKKAKKFVPASSRYVGLEAHGNCQVPSHLI
What is the function of this protein?
Cell-surface glycoprotein having a role in immunoadhesion.  Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1.  May have a role in capillary morphogenesis.
What are the official names of this protein?
E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2.
What is the protein family that this protein belongs to?
Belongs to the selectin/LECAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MTX2_GRARO
Sequence: YCQKWMWTCDEERKCCEGLVCRLWCKRIINM
What is the function of this protein?
Blocks mammalian Kv4. 2/KCND2 and Kv4. 3/KCND3 (By similarity).  Blocks mechanosensitive ion channels in rat astrocytes, without having effect on whole-cell voltage-sensitive currents (By similarity).
What are the official names of this protein?
Kappa-theraphotoxin-Gr2a, Kappa-TRTX-Gr2a, Toxin GsMTx-2, MTx2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MCP_EBVA8
Sequence: MASNEGVENRPFPYLTVDADLLSNLRQSAAEGLFHSFDLLVGKDAREAGIKFEVLLGVYTNAIQYVRFLETALAVSCVNTEFKDLSRMTDGKIQFRISVPTIAHGDGRRPSKQRTFIVVKNCHKHHISTEMELSMLDLEILHSIPETPVEYAEYVGAVKTVASALQFGVDALERGLINTVLSVKLRHAPPMFILQTLADPTFTERGFSKTVKSDLIAMFKRHLLEHSFFLDRAENMGSGFSQYVRSRLSEMVAAVSGESVLKGVSTYTTAKGGEPVGGVFIVTDNVLRQLLTFLGEEADNQIMGPSSYASFVVRGENLVTAVSYGRVMRTFEHFMARIVDSPEKAGSTKSDLPAVAAGVEDQPRVPISAAVIKLGNHAVAVESLQKMYNDTQSPYPLNRRMQYSYYFPVGLFMPNPKYTTSAAIKMLDNPTQQLPVEAWIVNKNNLLLAFNLQNALKVLCHPRLHTPAHTLNSLNAAPAPRDRRETYSLQHRRPNHMNVLVIVDEFYDNKYAAPVTDIALKCGLPTEDFLHPSNYDLLRLELHPLYDIYIGRDAGERARHRAVHRLMVGNLPTPLAPAAFQEARGQQFETATSLAHVVDQAVIETVQDTAYDTAYPAFFYVVEAMIHGFEEKFVMNVPLVSLCINTYWERAGRLAFVNSFSMIKFICRHLGNNAISKEAYSMYRKIYGELIALEQALMRLAGSDVVGDESVGQYVCALLDPNLLPPVAYTDIFTHLLTVSDRAPQIIIGNEVYADTLAAPQFIERVGNMDEMAAQFVALYGYRVNGDHDHDFRLHLGPYVDEGHADVLEKIFYYVFLPTCTNAHMCGLGVDFQHVAQTLAYNGPAFSHHFTRDEDILDNLENGTLRDLLEISDLRPTVGMIRDLSASFMTCPTFTRTVRVSVDNDVTQQLAPNPADKRTEQTVLVNGLVAFAFSERTRAVTQCLFHAIPFHMFYGDPRVAATMHQDVATFVMRNPQQRAVEAFNRPEQLFAEYREWHRSPMGKYAAECLPSLVSISGMTAMHIKMSPMAYIAQAKLKIHPGVAMTVVRTDEILSENILFSSRASTSMFIGTPNVSRREARVDAVTFEVHHEMASIDTGLSYSSTMTPARVAAITTDMGIHTQDFFSVFPAEAFGNQQVNDYIKAKVGAQRNGTLLRDPRTYLAGMTNVNGAPGLCHGQQATCEIIVTPVTADVAYFQKSNSPRGRAACVVSCENYNQEVAEGLIYDHSRPDAAYEYRSTVNPWASQLGSLGDIMYNSSYRQTAVPGLYSPCRAFFNKEELLRNNRGLYNMVNEYSQRLGGHPATSNTEVQFVVIAGTDVFLEQPCSFLQEAFPALSASSRALIDEFMSVKQTHAPIHYGHYIIEEVAPVRRILKFGNKVVF
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=16 symmetry, about 200 nm in diameter, and consisting of 150 hexons and 12 pentons (total of 162 capsomers).  Hexons form the edges and faces of the capsid and are each composed of six MCP molecules.  In contrast, one penton is found at each of the 12 vertices.  Eleven of the pentons are MCP pentamers, while the last vertex is occupied by the portal complex.  The capsid is surrounded by a layer of proteinaceous material designated the tegument which, in turn, is enclosed in an envelope of host cell-derived lipids containing virus-encoded glycoproteins.
What are the official names of this protein?
Major capsid protein, MCP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ASK1_CANGA
Sequence: MDRELERLDQEITLELQKIDGNLSHCFDVITKQVIPRVVAYGQVCDAISDSCEWLGTLCKSSGVVDLKRDVLLERTPVRDSDAHGNAHGDTHGNAHGDAHGEANAERSYGDVAGGEEHNSTVQSEVSDSTMGKYREDDTREQGEDDSVQRQKKRKVSLLIQERYGSSSSVMPSPDKRVPQQSLGSSPVKEQVPLPGTVIHFSTK
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit ASK1, Associated with spindles and kinetochores protein 1, Outer kinetochore protein ASK1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex ASK1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: TRUD_METBF
Sequence: MQVPEIEKQIGITLYSTDTDGLGGQLRQEVEDFIVKEITNREEGQEGKYLILELIKRDWDTHHLTRTLAKILQVSQKRISVAGTKDKRALTTQKISIFDIDAQKIEKIHLKDVELKVLGRSRKSVELGDLWGNNFRITIRNITHSSEEIHKLLEKTTNEILAQNGVPNFFGIQRFGSVRPVTHLVGKAIVEGDFEKAALLYIAEPFPDEPEDTRKARQFVKETLDFKEGLKIYPLHLGHERAMMNHLIANPDDFAGAFLVLPKNLYRMFVHGYQSYIYNIILCRRIEKGLSLNEAVEGDVVCFKNEHGLPDSSKTEKATTETVNAMNRLIKKKRAFITAPLPGHNTEFASGIPGEVEQAVLDELKVPLQGFNIEETPEMSSKGTRRELLLQVEPKFEVAEDELNPGKLKAVLEFMLPKGSYATTVLREYMKVDPLQMS
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CEEP_RUMA7
Sequence: MMISEIRQELTDHIIPFWNKLRDDENGGFYGYLSYGLELDKKADKGVILHSRILWFYSNAYMTLGGDELLDNAKHAYEFIKNNCIDYEYGGVYWMMDFEGKPADTMKHTYNIAFAIYALSSYYRASGDKEALALAYRLFEDIEKNTLDEYGYREAFDRQWRLVDNEALSENGLKADKTMNAILHLIEAYTELYKADGNEKVADRLKFQLGQMRDIVYTPDTNALKVFFDTAFNLVGDIHSYGHDIEATWLMDRACDVLGDEDLKKQFAEMDLKISHNIQDIALEDGALNNERDKNEIDKTRVWWVQAEAVVGFINAYQHSGDEKFLESAKSVWENIKEYIIDKREGGEWYSEVTFDHTPHDYKETVGPWKCPYHNGRMCMEVITRGVDI
What is the function of this protein?
Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).
What are the official names of this protein?
Cellobiose 2-epimerase, CE.
What is the protein family that this protein belongs to?
Belongs to the cellobiose 2-epimerase family.
Protein: PSD_COXBR
Sequence: MTKLHKYLPQRTLSKIVGWLATREWGLLTQWAIRLFIRHYGINMQEAQYPDIGHYPSFNAFFTRYLKRELRPVVEEPRAIASPVDGIISEMGQIKGENLIQAKNHHYTITALLGEDPSRASQFLDGDFFTAYLAPKNYHRIHMPLDGRLIEMIHIPGKLFSVNPASVQTVPRLFARNERAVCLFETENGLMAVILVGAMLVGSINTVWHGTVVPTAEGIAVHNYREKNIKFKRGEEIGHFKMGSTVILLFPKNTIQWNPNCQPKGTICYGENIGTVSLIEVA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYB_SYNBO
Sequence: MTIIRKKHPLIKLINHSFIDLPTPSNISSWWNFGSLLGLCLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDLLGALLLLTALMILVLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAFMPLLHTSKQRGITFRPITQTMYWILVSDLLILTWIGGQPVEYPFIMIGQVASITYFAIIVIFMPIAGIIENNILGLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FOLM_ECOUT
Sequence: MGKTQSLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLIKAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLTDVLACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.
Protein: PSAI_CYAPA
Sequence: MVSNLPSILVPMVGIVLPAIVMALLFVYIETDEIA
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: SYC_SALHS
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRT17_ONCMY
Sequence: MPRRRRSSSRPVRRRRRPRVSRRRRRRGRRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine TP17.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CYB5B_ARATH
Sequence: MGDEAKIFTLSEVSEHNQAHDCWIVINGKVYNVTKFLEDHPGGDDVLLSSTGKDATDDFEDVGHSESAREMMEQYYVGEIDPTTIPKKVKYTPPKQPHYNQDKTSEFIIKLLQFLVPLAILGLAVGIRIYTKSG
What is the function of this protein?
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases.
What are the official names of this protein?
Cytochrome b5 isoform B, AtCb5-B, Cytochrome b5 isoform 2, Cytochrome b5 isoform E, AtCb5-E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
Protein: ATPD_KLULA
Sequence: MFRLSAARTLAKSVNTVVAKRTYAEAADGALKLQFALPHQTLFSGTPVTQVNLPAKSGQIGILANHVPTVEQLVPGVVEVLEGSSSKKFFVSGGFATVQPDSTLAITSVEAFPLESFSPENVRSLLAEAQKNVSSADEVAAAEAAIQLEVLEALQAALK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit delta, mitochondrial, F-ATPase delta subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: SYT_BORHD
Sequence: MSEKLDRESILYKKRHSIAHVMAEAVLELFPNTKIAIGPPIKDGFYYDFDFEKHITEDDLLLIEQKMREILKTGSPFVKEVITKEQALMLFKDEPYKMDLIRGLAITDEISIYKSHNFTDLCKGPHVDNMGKIDPKAFKLTSIAGAYWRGDEKNKMLTRIYGTLWNNEKDLKAYLKLREEIKRRDHRKLGRELDLFSVHEDIGPGLIFFHPNGARIRAIIEDFWREEHFKNGYDVLFTPHIGKSCLWETSGHLDFYKESMFEKMEMDKSNYYVKPMNCPFHIAIYNTGKHSYRDLPFRWAELGTVYRYEKIGALHGTMRVRGFTQDDAHIICAYEQVKSEVQEVLRFALYMWNQFGFADLKAYLSTKPEKAVGDKDDWEMSVKVLEEALIDLNIAYDIDEGGGAFYGPKIDLKIIDSLGREWQMSTIQFDFNLPERFKMTYTAEDGKEKRPFMIHRALLGSIERFFGILVEHYGGAFPVWLAPLQVIIIPVNNVVEEYALEILSLFKNEGIRIKLDNDCNMRMNAKIRQYQSKKVPYMFIIGEKEVVEGKISIRTRTNDQINGLELKEALEFVRLKVKNKEIL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEN34_HUMAN
Sequence: MLVVEVANGRSLVWGAEAVQALRERLGVGGRTVGALPRGPRQNSRLGLPLLLMPEEARLLAEIGAVTLVSAPRPDSRHHSLALTSFKRQQEESFQEQSALAAEARETRRQELLEKITEGQAAKKQKLEQASGASSSQEAGSSQAAKEDETSDGQASGEQEEAGPSSSQAGPSNGVAPLPRSALLVQLATARPRPVKARPLDWRVQSKDWPHAGRPAHELRYSIYRDLWERGFFLSAAGKFGGDFLVYPGDPLRFHAHYIAQCWAPEDTIPLQDLVAAGRLGTSVRKTLLLCSPQPDGKVVYTSLQWASLQ
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  It probably carries the active site for 3'-splice site cleavage.  The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen34, Leukocyte receptor cluster member 5, tRNA-intron endonuclease Sen34, HsSen34.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=May be transiently localized in the nucleolus.
Protein: EZRA_BACC3
Sequence: MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVSTTIPKADKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHGHNDMVRQGYVLDYLEVPKEVRDMTKQLQTCLIDIQELHITEAAEKVENLKTRLDGFYDQLEQEVHARHYVEQKTLSVYEDLEEIRTETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILTKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSLEEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIAEYVDNEQTLS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.