PharMolix/UniProtQA huggingface dataset:
Protein: C14AA_BACTS
Sequence: MDCNLQSQQNIPYNVLAIPVSNVNALVDTAGDLKKAWEEFQKTGSFSLTALQQGFSASQGGAFNYLTLLQSGISLAGSFVPGGTFVAPIVNMVIGWLWPHKNKTADTENLIKLIDEEIQKQLNKALLDQDRNNWTSFLESIFDTSATVSNAIIDAQWSGTVDTTNRQQKTPTTSDYLNVVGKFDSADSSIITNENQIMNGNFDVAAAPYFVIGATLRLSLYQSYIKFCNSWIDAVGFSTNDANTQKANLARTKLTMRTTINEYTQRVMKVFKDSKNMPTIGTNKFSVDAYNVYVKGMTLNVLDMVAIWSSLYPNDYTSQTAIEQTRVTFSNMVGQEEGTDGTLKIYNTFDSLSYQHSLIPNNNVNLISYYTDELQNLELAVYTPKGGSGYAYPYGFILNYANSNYKYGDNDPTGKPLNKQDGPIQQINAATQNSKYLDGETINGIGASLPGYCTTGCSATEQPFSCTSTANSYKASCNPSDTNQKINALYAFTQTNVKGSTGKLGVLASLVPYDLNPKNVFGELDSDTNNVILKGIPAEKGYFPNNARPTVVKEWINGASAVPFYSGNTLFMTATNLTATQYKIRIRYANPNSDTQIGVLITQNGSQISNSNLTLYSTTDSSMSSNLPQNVYVTGENGNYTLLDLYSTTNVLSTGDITLKLTGGNQKIFIDRIEFIPTMPVPAPTNNTNNNNGDNGNNNPPHHGCAIAGTQQLCSGPPKFEQVSDLEKITTQVYMLFKSSSYEELALKVSSYQINQVALKVMALSDEKFCEEKRLLRKLVNKANQLLEARNLLVGGNFETTQNWVLGTNAYINYDSFLFNGNYLSLQPASGFFTSYAYQKIDESTLKPYTRYKVSGFIGQSNQVELIISRYGKEIDKILNVPYAGPLPITADASITCCAPEIDQCDGGQSDSHFFNYSIDVGALHPELNPGIEIGLKIVQSNGYITISNLEIIEERPLTEMEIQAVNRKDQKWKREKLLECASVSELLQPIINQIDSLFKDANWYNDILPHVTYQTLKNIIVPDLPKLKHWFIDHLPGEYHEIEQKMKEALKHAFTQLDEKNLIHNGHFATNLIDWQVEGDARMKVLENNALALQLSNWDSSVSQSIDILEFDEDKAYKLRVYAQGSGTIQFGNCEDEAIQFNTNSFVYKEKIIYFDTPSINLHIQSEGSEFVVSSIDLVELSDDE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry14Aa, 132 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryXIVA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: FAPR_BACCZ
Sequence: MKKRRSKKERQELLQQTIETNPFITDEDLAEKFQVSIQTVRLDRMELSIPELRERIKHVATKQHEEDVKSLPLEEVVGEIIDIELDRHAISIFEVKVEHVFKRNQIARGHHLFAQANSLAVAVIDEELALTAKSTIRYIRPVKLGERVVAKARVEDVENDKGRTVVKVRSFVGEELVFTGTFEMYRSSNYSEEGNNL
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: AMPPA_METM7
Sequence: MLFLNAKFIDLDLGESAVIVNEEDLKGTSYYPQDRVLIESHAGSVIGNIYSTKTMVQKGEVGMLVSELSEISISEGEEVKLRHAEKPESIPFIKKKMDGQVLNPHEIRTIIDEIVSKKLSNIELSAFVSSTYINGMNMDEISEMTKRIAETGDMISWEKSLVVDIHSIGGVPGNKYALLSIPILAAAGITVPKTSSRAITSPAGTADVMEVLTNVELKEEEIKRIVKTTNGCLAWGGGVNLAPADDIIINVERPVSIDPQPQLLASVMAKKIATGIKYTVIDIPVGKGVKIKNEAEGAKLARKFIELGEMLNIKVECVLTYGGQPLGRAIGPALEAKEAIESLQDPKNAPKSLIEKSLSLAGILLELGGAAQIGEGQNLAWEILESGKALEKFNQIIVEQGGTPKKPEEIELGEYVEEILAPIDGYITDISNTAITNVVKEAGAPRDKKAGILLNSKIGNKVTQGDVLYTIYSGSEERLISAVNLARRVYPVKVEGMLIERISKF
What is the function of this protein?
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P).  Exhibits phosphorylase activity toward CMP and UMP in addition to AMP.  Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
What are the official names of this protein?
AMP phosphorylase, AMPpase, Nucleoside monophosphate phosphorylase, NMP phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: ALGP_PSEAE
Sequence: MSANKKPVTTPLHLLQQLSHSLVEHLEGACKQALVDSEKLLAKLEKQRGKAQEKLHKARTKLQDAAKAGKTKAQAKARETISDLEEALDTLKARQADTRTYIVGLKRDVQESLKLAQGVGKVKEAAGKALESRKAKPATKPAAKAAAKPAVKTVAAKPAAKPAAKPAAKPAAKPAAKTAAAKPAAKPTAKPAAKPAAKPAAKTAAAKPAAKPAAKPVAKPAAKPAAKTAAAKPAAKPAAKPVAKPTAKPAAKTAAAKPAAKPAAKPAAKPAAKPVAKSAAAKPAAKPAAKPAAKPAAKPAAKPVAAKPAATKPATAPAAKPAATPSAPAAASSAASATPAAGSNGAAPTSAS
What is the function of this protein?
The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i. e.  under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process.
What are the official names of this protein?
Transcriptional regulatory protein AlgP, Alginate regulatory protein AlgR3.
Protein: RHLB_SHEAM
Sequence: MSETHLTQQKFADLPLCDEVKQALNENGFEHCTPIQALSLPVLLEKKDIAGQAQTGTGKTLAFLVATFNHLLTTPVPEHRQLNQPRAIVMAPTRELAIQIAKDATLLSKHSGLKVGIVYGGEGYEAQRKVLDKGVDVLIGTTGRIIDYVRQGVINLGAIQAVVLDEADRMFDLGFIKDIRFLFNRMPGAKERLNMLFSATLSMKVQELAYDHMNDPVKVEIAPEEKTSRNIKEEIFYPSMEDKLKLLHSLIEEDWPEKAIVFANTKYQCENLWASLEADGHRVGLLTGDVPQKKRLKILEQFTQSELDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGQKGVSVSFACEEYALNLPAIEDYIKHSIPVTSYDRDALIDIPPPVKIHRKPHAGGRNLRDRNGSPRPSGSHRSGSGRPPRHDRTRRHS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIN41_DANRE
Sequence: MCEVILWSSAQMASFPDSDLQTCPLCKELCGCSAPISSNSSTSSSSSQTSNSSSTSSTRRLHVLPCLHAFCRQCLEGQRSPGDPLKLRCPTCDQKVSLSESGVDALPSSNFLFSNLLDVVVSAEEQGKNGRSSAVVHHGGLLRPQHLSDPQCSSCDEGNPATSHCLDCQEYLCDNCVRAHQRVRLTKDHFIEGLLESLHLANRTNNSNTPVSISQSFHNSFSMLNVFQERMDFCQHHDDAVLRFFCDSCTVPICRECSLGRHAGHSFTYLQDALQDSRALTIQLLADAQQGRQAIQLSIEKAQAIAEQVELKAKVVQSEVKTITLRHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLHQNLTKLDSTIATVTQVLEEGRSIDVLLAREHMLNQLQELKSLRCILQPQEDDRIMFTPPDQALLIAIKSLGLISSGAFATASKAHGEGIKRALQGKPASFTVVGYDHDGEPRLSGGDSVSVVLMSPDGNLSSAEVSDHQDGTYTVSYLPKGEGEHLLSVLICNQHIEGSPFKVMVKSGRSYGGVGLPMASFGGEGDGDGQLCRPWGICVDKEGYVVVADRSNNRVQIFKPCGTFHHKFGTLGSRPGQFDRPAGVACDSQRRIIVADKDNHRIQIFTFDGQFLLKFGEKGTKNGQFNYPWDVAVNFEGKILVSDTRNHRVQLFGPDGTFLNKYGFEGALWKHFDSPRGVAFNQEGHLVVTDFNNHRLLVIRPDCQSARFLGSEGTGNGQFLRPQGVAVDQEDRIIVADSRNHRIQVFEPNGNFLCKFGTHGNGFGQMDRPSGIAVTPDGVIVAVDFGNNRILMF
What is the function of this protein?
E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance.  Binds to miRNAs and participates in post-transcriptional repression of transcripts.  Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM71, Protein lin-41 homolog, RING-type E3 ubiquitin transferase TRIM71, Tripartite motif-containing protein 71.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: HSLV_CAMLR
Sequence: MFHATTILAYKGKNKSVIGGDGQVSFGNTVLKNNAVKIRKLNNGKVLAGFAGSTADAFNLFDMFEKLLSSSKGDLLKAAIDFSKEWRKDKYLRKLEAMMLVLDRNHIFLLSGTGDVVEPEDGAIAAIGSGGNYALSAARALAKHSNLDEENLVKESLQIAGEICIYTNTNIKTYVIEDDK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEZA_XENLA
Sequence: MTAEFDEEVVFENSPLFQYLQDLGHTDFEICPLSKEEERLAENGQGKQDVHTTEKKSIISRTVEFLKSWSPFLSKKKKDEKIHLLEIGFRLESLRTILQQEVLIQEDVELIELLDPGILSAGQTQNQQNDHLPTLWSIATPNIWETSILFVFLSAVAAFQSWSISSSLIWGPSLILFAAFTVLKTLHTWRSARLRIILRKYCTQVEGTVSNSRAFTNLVRKALRLIQETEVISRGFTLVSAACPYGKAGQHASQHLLGLRKAVYRTVRTNFRISRLATLYMLKHYPLNSEIDNVTNYICVVPLKDLGLGLCEEHVSEEDAHNLTDAFSLPALKVLFQLWIGQSSEFFRRLALLLSPENASQGPSTSPEQLPHFIWSDVVQDLPHTQAACMAELKRSYEFYRYFETQHQSGLERTAKRKEVGELNNLHGAVRSLQLHLKALLNEVIVLEDELDKLSSCKEMQAVTPEASLMLEEKLRIIQPHVQASNTCWEEALCQVERMVRKPTTKKDTGKYSCENLNYPVVSNVPPAMRIEDRDPVPEEQILEAYVEEAVTDQEFNSEEIYLFSPEERERQKREREESRRVLQELKAVLGLKASEAERQKWKQLLFSEHAVITPLLPEEPVGHFEPLLSIYPEEPHKNLGFYGEIPSEINGTEHVKDAPIQVDHGNMNHEDEAKICPVSEEVEPASCKEEEDETPCPAPRTVLPPAIKERLARIHQSSDLNFTSGLATQVAARSLTFTFLQEQTFGDEWDDDDDNEDHDHDKERNNDSSQLEG
What is the function of this protein?
Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life.
What are the official names of this protein?
Vezatin.
What is the protein family that this protein belongs to?
Belongs to the vezatin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Nucleus.
Protein: CHEW_RHIEC
Sequence: MSYAVKSLNQGDRELIAFRIGDQEFCVNIMSVREIRGWTPATAMPHSPAYMLGVINLRGAVLPIIDLAARLGMKPADPTARHVIIVAQVRRKVVGLLVDAVSDILTVTDEIIQPTPEISSDLERQFARGILAIDKRMICLIELEALFSETESEAA
What is the function of this protein?
May be involved in the transmission of sensory signals.
What are the official names of this protein?
Probable chemotaxis protein CheW.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB4S_TITCO
Sequence: MQMKYLIPIFFLVLIVADHCHAFLGMIPGLIGGLISAFKGRRKRDITSQIEQYRNLQKREAELEDILANLPVY
What is the function of this protein?
Antimicrobial peptide (PubMed:27917162) (By similarity).  Has a high antibacterial activity against the Gram-positive bacterium S. aureus (MIC=5-17. 30 uM), the methicillin-resistant S. aureus (MRSA) (MIC=17. 30 uM), and E. faecalis (MIC=69. 23 uM) (By similarity).  Has antifungal activity against Candida spp.  and one Cryptococcus neoformans strains with MICs values ranging from 6. 25 to 100 uM (PubMed:27917162).  Shows also an inhibitory activity on C. albicans biofilms at high concentrations (PubMed:27917162).  Has a moderate hemolytic potency (18% at 20 uM) (By similarity).  Also inhibits the growth of the five cancer cell lines tested (By similarity).  In the model of polymicrobial sepsis, it exhibits an antibiotic effect, reducing the levels of microorganisms in the infectious focus and the inflammatory responses in the lung and cecum of septic animals (By similarity).
What are the official names of this protein?
Putative antimicrobial peptide clone 4, Non-disulfide-bridged peptide 4.23-like, NDBP-4.23-like.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRML_MYCPN
Sequence: MYKSAINIVLFCPEIPNNTGNIVRSCTAFKANLHLIKPYGFFLNDKRMVRAGLNCWDKVQMFEHKSWEHFIETTPPNKAIWLLTKSGTTTPDQINMQTDNREQLYFVFGQETKGLPQTLMEQYSQNQVRIPIWNPVRSINLSNTVACVLYEYAKQNHYFNLDKQCA
What is the function of this protein?
Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
What are the official names of this protein?
Putative tRNA (cytidine(34)-2'-O)-methyltransferase, tRNA (cytidine/uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_NEIMF
Sequence: MIYPKTYDVIVVGGGHAGTEAALAAARMGAQTLLLTHNIETLGQMSCNPSIGGIGKGHLVRELDALGGAMALATDKSGIQFRRLNASKGAAVRATRAQADRILYKATIREMLENQENLDLFQQAVEDVTLDGERISGVVTAMGVEFKARAVVLTAGTFLSGKIHIGLENYEGGRAGDPAAKSLGGRLRELNLPQGRLKTGTPPRIDGRTIDFSQLTEQPGDTPVPVMSVRGSADMHPRQVSCWITHTNTQTHDIIRSGFDRSPMFTGKIEGVGPRYCPSIEDKINRFADKDSHQIFLEPEGLTTHEYYPNGISTSLPFDIQIALVRSMKGLENAHILRPGYAIEYDYFDPRNLKASLETKTIQGLFFAGQINGTTGYEEAAAQGLLAGANAVQYVREQDPLLLRREQAYLGVLVDDLITKGVNEPYRMFTSRAEYRLQLREDNADMRLTEDGYKIGLVGEAQWRMFNEKREAIEREIQRLKTTWYTPQKLAEDEQIRVFGQKLSREANLHDLLRRPNLDYAALMTLEGAMPSERLSAEVVEQVEIQVKYQGYIDRQNEEIDSRRDIETLKLPDGIDYGKVKGLSAEVQQKLNQHKPETVGQASRISGVTPAAVALLMVHLKRGFKDAK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO72B_YEAST
Sequence: MILALGDFLTNRKTKHARGPGFNSQLAPFIFDYLFPIGRVTDFFYFFQGPFVL
What are the official names of this protein?
Uncharacterized protein YOR072W-B.
Protein: US15_HCMVM
Sequence: MRREKGFQVPTDGTVIYVPPGIQETRLATRSLAWVDCCRVALHTYGAVGWQLAGLTALLSAFCYAAPATWFHHSRLCLTESSPSLVFVIPVTSVIFIHCYETSHPSNIGVLLFYTLLHVPPLIVICLCLDGTLVISAALFTLLAFLSCTGVALLAPERTVRRQIVVIHALITLTFTAIVVVILRRGWSWCFKIVLSFSVLITCLAVSHFHEAALAVRYETPLERALLAAVKVFLSLVFTLLMVLRIMTLRTFLQTYFSSDKL
What are the official names of this protein?
Membrane protein US15.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 US12 protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: ACPS_STRZJ
Sequence: MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSISHTDQFVTASVILEENHES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_PROMP
Sequence: MTIFEGSFTNASTLKVGIVVARFNDLITNKILSGCLDCLKRHGLDTSETSKELDIVWVPGSFELPIAAKTLLKKTNYDVVIALGAVIRGETSHYDVVISEASKGISQVSYENNVPIIFGVLTTDSMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: GLMU_ECODH
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_CARHZ
Sequence: MVSSTKIAQMIDHTLLKATATYADIEKLCQEAKEFNFKSVCVNPAFVPFASQLLKDSEIKVCTVIGFPLGATSTAVKAYEASWAVENGALEVDMVINIGALKAGRYEEVLEDIKEVVSAAKGKNPTVVVKVIIETCYLTDEEKIKACELAVEAGADFVKTSTGFGTGGATVEDVRLMKRTVGEKAEVKASGGIRSFADAIKMIEAGATRLGTSSGVSIMQGLVSGEDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEN_MOUSE
Sequence: MVAGEVPESTQCPSLTSLNTKDVVRRRHKRRSRQHQRFMARKALLQEQELLSTAPGPGLCLLPSPSQMPAVTEASDSRRQRPKARSGSNGLCSKKSVPREAPRPGPIKCVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPSSLIRTRVSLKDLALNLLHKKIQVGHQGHSSVEDAMTAMELYQLVEVQWEQQVASSAQAPAEDRGPDSSTDVEQYMDDQYWPEDLTQSTGAETNGGPDRQEGEEGQGARSAPP
What is the function of this protein?
Exonuclease with activity against single- and double-stranded DNA and RNA.  Mediates p53-induced apoptosis.  When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity).
What are the official names of this protein?
Apoptosis-enhancing nuclease, Interferon-stimulated 20 kDa exonuclease-like 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction (By similarity).
Protein: RLMN_BACSU
Sequence: MAELNKTKVRKELRTERPSIYSFELDEIKQWLTDNGEKPFRAAQIFEWLYEKRVSSFEDMTNLSKDLREKLNTRFVLTTLKTAVKQTSQDGTMKFLFELHDGYTIETVLMRHEYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVAQVVKVQKALDETDERVSSVVIMGIGEPFDNFNEMLAFLKIINHDKGLNIGARHITVSTSGIIPKIYEFADQQMQINFAISLHAPNTEIRSRLMPINRAYKLPDLMEAVKYYINKTGRRISFEYGLFGGVNDQVEHAEELADLLEGVKCHVNLIPVNYVPERDYVRTPRDQIFAFEKTLKSRGVNVTIRREQGHDIDAACGQLRAKERQDETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_AZOC5
Sequence: MALRASWKGFLTVGALSCHVGLYAAASTSERISLHMVNRKTGHRLRRQYVDEETGEPVEADAQVKGYEVSKGEFVTVEPDEIADIVPAGTKTIAVNTFLACTDVDTAYFDRPYFLAPVDEPSAEVLKLLAAGMSERKVAALGEAVLFRRVRRLLIRPVAEGGALTACTLNFDYEVRSAQEQFADVPKTRISGEMLELATHIIRSKPGKFDPSAIEDRYEDALAALVRAKMEGKPLPKPEPRREEKVVSLLDALRASAGSPDKPAPKRAGAKGKAAGTKTAGSKAGSAKAGGSKATGTKTRKAKSAAASAGAQTRRTGTTRKAG
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: RIBB_SHESH
Sequence: MNQSLLSPFGTAIERVETALISLKQGRGVLVVDDEDRENEGDLIYSAETLTNEQMALLIREGSGIVCLCLPDERVKHLALPPMVENNSSQYGTAFTVSIEAKEGVTTGVSAADRVTTIKTAIADDAQPDDLARPGHVYPLRAQPGGVMTRRGHTEGTIDLMILAGLKPAGVLCEITNPDGTMARLAEIISFGAKHDLPVLTIEDIVEYRKSLMAEAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: GNGF_STRP1
Sequence: MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGELRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEMQGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYPGMIDHVYVTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVVYICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLVQVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP07_ARATH
Sequence: EQDRR
What are the official names of this protein?
34 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PFF1_LEPMJ
Sequence: MARYNPLAFTSGPVVFFITITYTALLIALLLTHLTLPSYPSHPPLGINLTQAWSDLEHITREFHPYNSHANDNVRAYLLSRIEHMMASKKLGSDQVQIIDDNISNATFSSGNTTVYFEGTNLIVAVRGSHDDQAFNDRNRRPDNGGVLVNAHYDSVSSGYGATDDGVGVVSVLQLLSFFTEPKNWPKRTVVLLLNNGEEDFLNGAKAFMRHDISQVPHTFVNLEGAGAGGRAAMFRSTDTHVTRFYRKSEHPFGTVVSGDGFKKGLVRSETDYKVFFEELGLAGLDIAFIEPRAKYHTIEDSTRETSLNSVWHMLSAAIATTSGLAADTSTPDRESHDDAVWFDIFGKVFIVFQLHTFFALCVTLLVVAPLTLIGLAWSLHKADRNYLFARKAFVYSADDDEPIHLYGWRGFFRFPIAFGIATSIVVGLAMMLSAWFAVSWFLLHGADAMRPSALQRMYSLLWLFIGSFCLLVFFTILANNHQVAAGYPSLFCFATVFLANVLSFLELFLAPPKSAYAWNVHQNADGGSRPLTSSATAARSDNRATTDDDATETTSLLSGNRRSFARHDAGRRDAINEGANSQEPESRRRLDLGQPHSGEQEWSGKLPSWIWIVQFSLLAPMIVILVGQIALLLTSALYQTPSDGNSPLYIYTSIAALAVFLVAPIGPFIHRFTHHVPTFLFLLCVATTIYNLVAFPFSEQHKLKVYFVQRVDCDTGVNTVSLTGLDGYVQRIAGNMPSAQQSSLNCSTPDIVTRKELRMCEWEGLHPNVVSPTSQYSNKTRATDWIDYEIFHDDSNNRGRR
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RP55_BRADU
Sequence: MALTQRLEFRQSQSLVMTPQLMQAIKLLQLSNLDLTTFVEEELERNPLLERANDEASGGEAPAEAGQFSDSDGGHNDEPGGGPGEAFEPGQEEWMSKDLGTRAEIEQTLDTGLDNVFSEEPAEAAARNAQDAAPTTYTEWGGGASGDEDYNLEAFVAAEVTLGDHLAEQLSVAFTAPAQRMIGQYLIDLVDEAGYLPPDLGQAAERLGASQQEVEDVLAVLQKFDPPGVCARNLSECLAIQLRELDRYDPAMQALVEHLDLLAKRDIAGLRKVCGVDDEDIADMIGEIRRLNPKPGMKFGAARLQTMVPDVYVRPGPDGGWHVELNSDTLPRVLVNQTYYSELSKKIGKDGDKSYFTDALQNATWLVRALDQRARTILKVATEIVRQQDGFFTHGVAHLRPLNLKAVADAIQMHESTVSRVTANKYMATNRGTFELKYFFTASIASADGGEAHSAEAVRHHIKQLIDSEAPAAILSDDTIVERLRASGIDIARRTVAKYREAMRIPSSVQRRRDKQSALGNVLSTAMSDRSRNPEPA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of the nitrogen fixation genes.
What are the official names of this protein?
RNA polymerase sigma-54 factor 2.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: ACDA1_PYRFU
Sequence: MSLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYKSVLEIPDEVDMAVIVVPAKFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEKIGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIVIKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGDNVVIITNGGGIGVMATDAAEEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADGKSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIREYNESGRKKPLVVAIVGGIEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK
What is the function of this protein?
Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate.  Can use other substrates such as isobutyryl-CoA, propionyl-CoA and butyryl-CoA, but not indoleacetyl-CoA, phenylacetyl-CoA or succinyl-CoA.  Seems to be involved primarily in the conversion of acetyl-CoA to acetate.  Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters.
What are the official names of this protein?
Acetate--CoA ligase [ADP-forming] I subunit alpha, ADP-forming acetyl coenzyme A synthetase I subunit alpha, ACS I subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the acetate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.