PharMolix/UniProtQA huggingface dataset:
Protein: ASNA_STRZT
Sequence: MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERW_ECOLX
Sequence: MQLNTRQARIFKLANLLGTGKPVSAADIITSLECSEPTLTRALKELRESYSAEIKYSKAGHSYHLVNPGQLDKKTLRRMNEALAQNAELKTGESTGKVVLDKDKKTAVSLSLRMRILRKIDRLAALSGSTRSEAVEKLALHSVDELIKEYSAKKS
What is the function of this protein?
Involved in tellurite resistance (Ref. 2).  TerW binds specifically to the potential promoter region of the terZABCDE operon and probably regulates expression of the genes (Ref. 2).
What are the official names of this protein?
Probable tellurium resistance transcriptional regulator TerW.
Protein: SPED_XYLFA
Sequence: MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVAEIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVAHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKHFIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFKERMKIEALLKLEIEELFHGRNLAE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: SPE2C_STRPU
Sequence: MAVQLFFTEEQRKVFKSSFKSIDADGDGKITPEELKAAFKSIEIELTQEKIDEMMSMVDKDGSRPVDFSEILMKKAEQMRGKGAQYFKAFDALDTDKSGSLSPEELRTALSACTDPPMTKEEIDAIIKKADGNNDGEIRRAEFVRMIQSSY
What is the function of this protein?
Calcium-binding protein involved in larval development and metamorphosis.  Likely to function as calcium buffers mediating the transport of calcium from the sea water to the blastocoel where calcium is required for skeleton formation.
What are the official names of this protein?
Calcium-binding protein SPEC 2C.
Protein: NAGB_STRAW
Sequence: MEVVIVPDARAGGELIAEAMAQLLGRKPEALLGVATGSTPLPIYEALAAQVKSGAVDASRARIAQLDEYVGLPAEHPESYRSVLRREVLEPLGLGMDAFMGPDGTAEDVQGACEAYDKALAAAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRVDNARFFDGDIEQVPHHVITQGIGTILEARHLVLLATGEGKADAVAATVEGPVAAVCPASALQLHPHATVVVDDAAASKLKLADYFRHTYAGKPDWQGI
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ASY1_ARATH
Sequence: MVMAQKLKEAEITEQDSLLLTRNLLRIAIFNISYIRGLFPEKYFNDKSVPALDMKIKKLMPMDAESRRLIDWMEKGVYDALQRKYLKTLMFSICETVDGPMIEEYSFSFSYSDSDSQDVMMNINRTGNKKNGGIFNSTADITPNQMRSSACKMVRTLVQLMRTLDKMPDERTIVMKLLYYDDVTPPDYEPPFFRGCTEDEAQYVWTKNPLRMEIGNVNSKHLVLTLKVKSVLDPCEDENDDMQDDGKSIGPDSVHDDQPSDSDSEISQTQENQFIVAPVEKQDDDDGEVDEDDNTQDPAENEQQLARVKDWINSRHLDTLELTDILANFPDISIVLSEEIMDQLVTEGVLSKTGKDMYIKKRDKTPESEFTFVKEEADGQISPGKSVAPEDYLYMKALYHSLPMKYVTITKLHNMLDGEANQTAVRKLMDRMTQEGYVEASSNRRLGKRVIHSSLTEKKLNEVRKVLATDDMDVDVTETINKTNGPDAKVTADVSTCGGIHSIGSDFTRTKGRSGGMQQNGSVLSEQTISKAGNTPISNKAQPAASRESFAVHGGAVKEAETVNCSQASQDRRGRKTSMVREPILQYSKRQKSQAN
What is the function of this protein?
Required for normal meiosis in male and female gametophytes.  Plays a crucial role in coordinating the activity of DMC1, a key member of the homologous recombination machinery (PubMed:18504359).  Acts at the interface between the developing chromosome axes and the recombination machinery to ensure DMC1-mediated interhomolog recombination (PubMed:17785529).
What are the official names of this protein?
Meiosis-specific protein ASY1, Protein ASYNAPTIC 1, AtASY1.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=During interphase-early leptotene, distributed as numerous punctuate foci throughout the chromatin. At zygotene and pachytene, shows a continuous localization along chromosomal axes.
Protein: AMYB_DROYA
Sequence: MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGFAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSGNEQQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSTKSFPGVPYSSLDFNPTCSINNYNDANQVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKTLNTDHGFNSGSKAYIVQEVIDMGGEAISKSEYTGLGAVTEFRHSDSIGKVFRGKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFSDTDQGPPTTDGHNIASPVFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGSDAIQNWWDNGSNQIAFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVSVGSDGRASIYLGSSEDDGVLAIHVNAKL
What are the official names of this protein?
Alpha-amylase B, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RIMK1_SHESA
Sequence: MKIGILSQFPELYSTRRLVAACESRGHEAVVINTLNCYMNINSIKPSIHYQGQELTGFDAIIPRIHASVTFYGCAVVRQFEMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPITGFANKPNDIPDLINMVGGAPLVIKLLEGTQGIGVVLAETKTAAESVIEAFLGLKANIMVQEYIKESNGSDIRCFVVGDKVVASMKRQGPEGDFRSNLHLGGCGEKVKITPAERKMAVAAVKAMGLVVAGVDILRSNRGPLILEVNSAPGIEGIEQTTGISVTEPIVEYIEKMVSARKSNRAVIA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: MINE_TRIEI
Sequence: MLNEIIEKLFYRNNPKSREEVKRRLKLVIAHDRADLNPEIIQAMRKDIIDVVSRYVEIDDTDSEFLLENNQRATSLVANLPIRRIKAKPTQDQED
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GLGB_PROMT
Sequence: MTVSILLDSLKDDGQRLSECRHESPFSILGPQPFKDKWIIRIWMPEASQVELVTQQTKIKLQNPNHEWIFEGVLEKDPGTDYQIKVNRGGIEHVQHDPWSFRKEWMGEIDRHLFAEGNHHHIWRKMGAHLTEIDKKKGVMFCLWAPHAKSVSVIGDLNSWDGRHHPMQKRLGGIWELFIPGLSEGDLYKYEIRTEKGHCYEKADPYGFQHEVRPAKSSVISKIDSFQWSDQSWISNRDNRDPLEQPISVYEMHLGSWMHASSDDPFINSNGEHRAPVPAADMKPGSRLLTYKELANKVIPYVKERGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRFGSPDEFRAFVDSCHKEGIGIILDWVPGHFPKDQHGLAYFDGSHLYEHSDPRVGEHKEWGTLIFNYSRNEVRNFLVANLIFWFDQFHIDGIRVDAVASMLYKDYLRPEGEWIPNEDGGNENFEAVRFLQQANHVLFQHFPGALSIAEESTTWTGVTKPTDMDGLGFNLKWNMGWMHDMLDYFEIDPWFRQFNQNNITFSICYNFTENFMLALSHDEVVHGKSHLLHKMPGDDWQKYANTRALLAYMWTHPGKKTIFMGMEFGQRQEWNVWDDLQWDLLNYEPHKGIQKLVDDLNNLYKREPALWRNDFDEYGFQWIDCDDNKNSVISFMRREKTDGEWLVIVANFTPQNHSNYRIGVPVDGFYEEIFNTDASQYGGSNLGNMGGKSTDLYNIHGYENSIDLCLPPLSVLVLKHKSKKN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PYRC_SPHAL
Sequence: MTDRLTIRRPDDWHVHLRDGAMLAHVAPYTARQFARAIVMPNLSPPVTTAEEGRAYRDRITAAVPADLDFTPLIVAYLTDATDADEIARGHAEGVFTAAKLYPAHATTGSAHGVTDVANIMGVLERMQDIGMPLLIHGEVTDHDVDIFDREAVFIERTLEPLVRALPGLKIVFEHITTAEAAQFVADAPANVAATITPQHLHINRNAMLVGGIRPHAYCLPVAKREHHRLAVRAAATSGSPKFFLGTDSAPHAVHMKEASCGCAGIFNAPFALESYAMAFDQDGALANFEGFASEHGPRFYGLPLNEGTVTLERAEITVPDRIGDVVPFHAGETIGWRLV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RPPH_BURM9
Sequence: MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RAG2_ORYSJ
Sequence: MASNKVVFSALLLIIVSVLAATATMADHHKDQVVYSLGERCQPGMGYPMYSLPRCRAVVKRQCVGHGAPGGAVDEQLRQDCCRQLAAVDDSWCRCSALNHMVGGIYRELGATDVGHPMAEVFPGCRRGDLERAAASLPAFCNVDIPNGTGGVCYWLGYPRTPRTGH
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Seed allergenic protein RAG2, Seed allergenic protein RA14.
What is the protein family that this protein belongs to?
Belongs to the cereal trypsin/alpha-amylase inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIP2_YEAST
Sequence: MSHKRRGLVIYQDQKQQQQHPPGQSLSSISWSPTRRPHHPLKQQSTNSFSEILSKSSVQPNVQHDGNHMPISLLVLKQEHHKQQQQQQQRQNIRSQNSTPPLRQLVQESQWTSSASNSSLKKQEKQPQTFYNTDSKLVSQLHSSVKDLDAIIQTHKPKFDTIIRDFSQATILSSNELLIKLPKDQTIILHSRAPKINAEWLQNKVNDPSASLVIDSRSFLTLCNNIKWYLHWKFI
What are the official names of this protein?
Uncharacterized protein YIL152W.
Protein: RL21_FRATH
Sequence: MYAIIKNGGKQYKVKEGEVVKLEKFDLGIGEKVEFDTVLMGQTAAGEVKIGAPTVAGAKVVGEVVEQGRHKKVKIMKFRRRKHSMKQQGHRQYFTAVKVSSISL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ATPE_MYCTU
Sequence: MAELNVEIVAVDRNIWSGTAKFLFTRTTVGEIGILPRHIPLVAQLVDDAMVRVEREGEKDLRIAVDGGFLSVTEEGVSILAESAEFESEIDEAAAKQDSESDDPRIAARGRARLRAVGAID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS13_DESRM
Sequence: MARIAGVDLPKDKRAEIALTYIYGIGKPTAQKILAQTGVNPDTRIKDLTEEEVNKLRDYIDKNTKVEGDLRREVALNIKRLIEIGCYRGIRHRRGLPVRGQRTKTNARTRKGPKKTVGARRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EFG_HAEDU
Sequence: MARTTPISLYRNIGISAHIDAGKTTTTERILFYTGVSHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMSQQYQQHRINVIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYGVPRIAFVNKMDRTGANFLRVVEQIKTRLGGNVVALQLPIGAEDNFTGIVDLVKMKAINWNEADQGMTFTYEDIPAEMLSECEERRAMLVEAAAEASEELMEKFFEAGDLSEEEIKTALRQRVLAGEIIPVCCGSAFKNKGVQAMLDAVIDYLPAPTDIPAIKGINEDESEGERHASDEEPFAALAFKIATDPFVGNLTFFRVYSGVINSGDTVYNSVKQKRERFGRIVQMHANKREEIKEVRAGDIAAAIGLKEVGTGDTLCAQNAPIILERMEFPEPVISVAVEPKTKADQEKMGLALGRLAQEDPSFRVHTDEESGETIISGMGELHLDIIVDRMRREFKVEANIGKPQVSYRETIRTRVNDVEGKHAKQSGGRGQYGHVVIDLYPLDAEGPGYEFVNEIKGGVIPGEFIPAVDKGIQEQLKSGPLAGYPVEDIGVRLHFGSYHDVDSSELAFKLAASLAFKAAFAKANPVLLEPIMKVEVETPPDYVGDVIGDLSRRRAMVNGQEATEFVVKINAEVPLSEMFGYATDLRSQTQGRASYSMEPLKYSEAPTSVAAAIIEARKAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDNRA_PIG
Sequence: METFCFRVSFWVALLGCVISDNPESHSTNLSTHVDDFTTFRGTEFSLVVTTHRPTNLALPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFENHDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEEHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHEQNNHNTERSSHKDSIN
What is the function of this protein?
Receptor for endothelin-1.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
What are the official names of this protein?
Endothelin-1 receptor, Endothelin receptor type A, ET-A, ET-AR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS3_METHJ
Sequence: MYQRDGNHTMITIKFDEKGLVPVIAQDKTTKDVLMLAYANKEAVDLTRSTGYAHYYSRSRNKLWKKGEESGHLQKVHEILVDCDEDAVIYLVDQLTAACHTGYRSCFYRRLDGTVSGERMFDPDEVYKKSE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S3_HUMAN
Sequence: MASQGRRRRPLRRPETVVPGEATETDSERSASSSEEEELYLGPSGPTRGRPTGLRVAGEAAETDSEPEPEPEPTAAPRDLPPLVVQRESAEEAWGTEEAPAPAPARSLLQLRLAESQARLDHDVAAAVSGVYRRAGRDVAALASRLAAAQAAGLAAAHSVRLARGDLCALAERLDIVAGCRLLPDIRGVPGTEPEKDPGPRA
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Plays a role in intracellular vesicle trafficking.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 3, BLOC-1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S3 family.
Protein: Y1441_STAAR
Sequence: MNAYDAYMKEIAQQMRGELTQNGFTSLETSEEVSEYMNQVNADDTTFVVINSTCGCAAGLARPAAVAVATQNEHRPTNTVTVFAGQDKEATATMREFIQQVPSSPSYALFKGRDLVYFMPREFIEGRDINDIAMDLKDAFDENCK
What are the official names of this protein?
UPF0403 protein SAR1441.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: ACTN4_CHICK
Sequence: MVDYHSAGQPYPYGGNGPGPNGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVNVVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRSPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINTGWQHLEQAEKGYEEWLLNEIRRLEPLDHLAEKFRQKASIHEAWTEGKEAMLKQKDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDVLGSLTHSRREALEKTEKQLETIDELHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLIAAHDQFKATLPDADREREAILGIQREAQRIADLHSIKLSGNNPYTSVTPQVINSKWERVQQLVPTRDRALQDEQSRQQCNERLRRQFAGQANIVGPWMQTKMEEIGRISIEMHGTLEDQLQHLKHYEQSIVDYKPNLELLEHEHQLVEEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHCGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSLVDPNGSGSVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNYITAEELRRELPPEQAEYCIARMAPYRGPDAAPGALDYKSFSTALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein.  Probably involved in vesicular trafficking via its association with the CART complex.  Involved in tight junction assembly in epithelial cells.  May also function as a transcriptional coactivator, stimulating transcription mediated by nuclear hormone receptors.
What are the official names of this protein?
Alpha-actinin-4, Non-muscle alpha-actinin 4.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Cytoplasm, perinuclear region.
Protein: CHIC1_MOUSE
Sequence: MSILLPNMAEFDTISELEEEEEAATSSSSPSSSPSSSSSSSVSGPDEDEEDEEEEEEEDEEEEDEEEEEEEVPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNSCLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLLEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
What are the official names of this protein?
Cysteine-rich hydrophobic domain-containing protein 1, Brain X-linked protein.
What is the protein family that this protein belongs to?
Belongs to the CHIC family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Protein: PLSX_STRT2
Sequence: MHVIAVDAMGGDNAPQAIVEGVNQALAEFKDIEIQLYGDEAKIKNYLIANERVSIVHTDEKINSDDEPVKAIRKKKKASMVLGAQAVKEKAADAVISAGNTGALLAAGLFVVGRIKGVERPGLMSTMPSFTGQPFDMLDLGANAENTANHLHQYAILGSFYAKNVRGIATPRVGLLNNGTEKTKGDSLRKEAFELLSQEASINFIGNVEAREIMSGAADVVVADGFTGNAVLKAIEGTGLGTMKTLKSAIMNGGLKAKLGAFLLKDRLKGMKETMDYSSAGGAVLFGLKAPVVKCHGSSDAKAVYYTIKQVRKMLDTKVVEQLVDAFDPKEEVN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SUSD_BACTN
Sequence: MKTKYIKQLFSAALIAVLSSGVTSCINDLDISPIDPQTGGSFDQQGVFVKGYAMLGVTGQKGIDGSPDLDGQDEGESGFYRTTFNCNELPTDECLWAWQENQDIPQLTSISWSPSSQRTEWVYVRLGYDITQYNFFLDQTEGMTDAETLRQRAEIRFLRALHYWYFLDLFGKAPFKEHFSNDLPVEKKGTELYTYIQNELNEIEADMYEPRQAPFGRADKAANWLLRARLYLNAGVYTGQTDYAKAEEYASKVIGSAYKLCTNYSELFMADNDENENAMQEIILPIRQDGVKTRNYGGSTYLVCGTRVAGMPRMGTTNGWSCIFARAAMVQKFFSNLEDVPMLPADVEIPTKGLDTDEQIDAFDAEHGIRTEDMIKAAGDDRALLYSGVGGGRRKIQTDAISGFTDGLSIVKWQNYRSDGKPVSHATYPDTDIPLFRLAEAYLTRAEAIFRQGGDATGDINELRKRANCTRKVQTVTEQELIDEWAREFYLEGRRRSDLVRFGMFTTNKYLWDWKGGAMNGTSVASYYNKYPIPVSDINNNRNMSQNEGYK
What is the function of this protein?
Major starch-binding protein present at the surface of the cell.  Mediates starch-binding before starch transport in the periplasm for degradation.
What are the official names of this protein?
Starch-binding protein SusD, Starch-utilization system protein D.
What is the protein family that this protein belongs to?
Belongs to the SusD family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DYR_STAEQ
Sequence: MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGRKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMIDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: AMZA_PYRAE
Sequence: MRPRITVVAPSRIKPLEIPEFTTIWQFKDIDISHFLDLARGQCRADKVVEALSNGVKSPTVYVLDCDGYYPGLNFVFGLAVPVLKTAVVFTARLVGPRFEERLVKEITHEAGHLYGLAHCANPSCVMYFSNSLLDTDRKSPYFCPKCRENLARIL
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: Y4331_ARATH
Sequence: MGLLKKKDSTSARSSTSPCADLRNAYHNCFNKWYSEKFVKGQWDKEECVAEWKKYRDCLSENLDGKLLTRILEVDGELNPTKQATDSKESSS
What are the official names of this protein?
Uncharacterized protein At4g33100.
What is the protein family that this protein belongs to?
Belongs to the TRIAP1/MDM35 family.
Protein: HIS1_CLOAB
Sequence: MDKNKTIRIALTKGRLEKAAVEIFENIGLDCSELKDKGRKLIFHDFKNSIDFVLVKAPDVLTYVEHGAADIGIVGKDTLLEMKKDFYEVLDLKVGKCKFSLASISSFKLNEGFNRMKIATKYPNVTREYFREKGIDVEIIKIEGSVELAPILNLADAIVDIVETGTTLKENGLVIFDDICDISARMIVNRASMKLNKDRITDIIQKVKNYVERES
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLR_BOMMO
Sequence: MADKDKKVKKKKAKEDAPAEEAPAAAAPAGDRQSSRGSRKAKRTGSNVFSMFSQKQVAEFKEAFQLMDHDKDGIIGKNDLRATFDSLGRLASEKELDEMVGEASGPINFTQLLTLFANRMSGGSDEDDVVINAFKTFDEEGKIDSERLRHALMTWGDKFSADEVDEAYDQMDIDDKGYIDTTKLIAMLTASAEEEEGGEAA
What are the official names of this protein?
Myosin regulatory light chain 2, MLC-2.
Protein: CLPX_ACIC1
Sequence: MARLGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSESHEPKFDQLPKPREICEFLDQYVIGQETAKKALSVAVYNHYKRIQVGGSSRSSNDSVELAKSNILLIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFAGLEKIIEARIGKKGIGFTATLHGKRDLNTADIFSHVMPEDLLKYGMIPEFVGRLPVITTVTSLDREALIRILTEPKNALVRQYQRLFELDSVDLEFTDDALEAIADQAILRGTGARGLRAIMEEVLLSVMYDIPSRTDVARVVITRDVVLNNVNPTLVPRDSVVAKRERREKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.