PharMolix/UniProtQA huggingface dataset:
Protein: SYA_CLOBK
Sequence: MERMGLNEIREEYLKFFESKAHLRLPSFSLVPKNDKSLLLINAGMAPLKPYFTGLQVPPNKRVTTCQKCVRTGDIENVGKTSRHGTFFEMMGNFSFGDYFKKEIIPWAWEFITEILKLPKDKLYVTIYEDDDEALDIWVNKTDVDPKRIFRLGKEDNFWEHGLGPCGPCSEIHFDRGAGEVKTSEEFVKASDEDKIVEFWNLVFTQFDKDEEGNYNKLANPNIDTGMGLERMATIMQNVDTIFEVDTIKAVLDKVCELSGANYKEDRVKDISIRIITDHIRSITFMISDGILPSNEGRGYVLRRLLRRAARHGKTLGIKNTFLHNLTDIVIENCYKNYPELEEKREYIKKVIKLEEERFDETIDAGMQILNDYIKEVKNNNHKVLSGDKAFKLYDTYGFPVELTEEILEEEGISIDKEGFNKEMKEQRERARSAREETNYMGSEDTILNKIDLNINTDFEGYDKLEVKSKVAVIIKDEEFKNGMEKGNEGVIVTYNTPFYAEMGGQIGDTGIIYNDSFKAEVIDCKKNISGKVLHFVKILDGKVALEDQVILKVNEERRNNIRKNHTATHILHAALIKVVGDHVQQSGSYVDDERLRFDFSHFEAVSEDELKEVEKIVNKEIMKANAVNTKVMNIEEAKEQGAIALFDNKYKDDVRVVSVGNFSKELCGGTHVSNSGQIGMFKIVSEAGVAAGIRRIEAVTAFKAMEYVDHKNNILKEAAQILKCNEKELLNKLNHQVLEMKEKEKEIEALKLKLASGAEDEILNNIREIKGVKVASAAVKDIDGNALRDLGDKIRDNMQSGVVVLGSNYKGKVLFVAMATKDTVAKGVHCGKIIKEVATIAGGGGGGRPDMAQAGGKDPNKLEDAIKTVETVVESLVK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z512B_HUMAN
Sequence: MTDPFCVGGRRLPGSSKSGPGKDGSRKEVRLPMLHDPPKMGMPVVRGGQTVPGQAPLCFDPGSPASDKTEGKKKGRPKAENQALRDIPLSLMNDWKDEFKAHSRVKCPNSGCWLEFPSIYGLKYHYQRCQGGAISDRLAFPCPFCEAAFTSKTQLEKHRIWNHMDRPLPASKPGPISRPVTISRPVGVSKPIGVSKPVTIGKPVGVSKPIGISKPVSVGRPMPVTKAIPVTRPVPVTKPVTVSRPMPVTKAMPVTKPITVTKSVPVTKPVPVTKPITVTKLVTVTKPVPVTKPVTVSRPIVVSKPVTVSRPIAISRHTPPCKMVLLTRSENKAPRATGRNSGKKRAADSLDTCPIPPKQARPENGEYGPSSMGQSSAFQLSADTSSGSLSPGSRPSGGMEALKAAGPASPPEEDPERTKHRRKQKTPKKFTGEQPSISGTFGLKGLVKAEDKARVHRSKKQEGPGPEDARKKVPAAPITVSKEAPAPVAHPAPGGPEEQWQRAIHERGEAVCPTCNVVTRKTLVGLKKHMEVCQKLQDALKCQHCRKQFKSKAGLNYHTMAEHSAKPSDAEASEGGEQEERERLRKVLKQMGRLRCPQEGCGAAFSSLMGYQYHQRRCGKPPCEVDSPSFPCTHCGKTYRSKAGHDYHVRSEHTAPPPEEPTDKSPEAEDPLGVERTPSGRVRRTSAQVAVFHLQEIAEDELARDWTKRRMKDDLVPETARLNYTRPGLPTLNPQLLEAWKNEVKEKGHVNCPNDCCEAIYSSVSGLKAHLASCSKGAHLAGKYRCLLCPKEFSSESGVKYHILKTHAENWFRTSADPPPKHRSQDSLVPKKEKKKNLAGGKKRGRKPKERTPEEPVAKLPPRRDDWPPGCRDKGARGSTGRKVGVSKAPEK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 512B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_ACIBC
Sequence: MNSAEIMADLSNHTPMMQQYLKVKKDYQHALLFYRMGDFYELFFEDAHLAAKLLGITLTHRGKANGNPIPMAGVPYHSAEGYLARLVKAGRTVAICEQVGEVTGKGPVERKVVRILTPGTLTDDALLTSYQSSNLVALCIHQNQIGFALLDLSAGIFKVQQQDYKPEQLPIELARLMPSEILIDEDLVDPNIIEQIKKHLDCPVTKRPNVDFNLNNAQKTLCDQFSVSTLSGFGLDPLPLAKAAAAALIHYAKETQKTALPHIRSILLEQSSDFIALDPITRRNLEIIEPLFEHGTSLFQLVNDCQTAMGGRLLSRTLMQPVRDTALLDARLDAIEQLIQGYHESPVRLVLKEIGDIERVLSRVALGSARPRDLVQLRHACAQIPFLRNALAPVVQAKKSKLLGQLDQELGDFKSLHQHLMAAIVENPPVLLRDGNVIAEGYDAELDELRQIRDHAGQFLIDLEIKERERTGISTLKIGYNRVSGYYIELTRAQAEQAPADYIRRQTLKNAERYITPELKSFEDKVLSSESRALAREKALFEALLENLRENIAHLQMMSSAIAQIDVIANFAHQARLNNWARPEFTPETGIKIQGGRHPVVEALSKAPFTPNDTFLDVQHRMAIITGPNMGGKSTFMRQTALISLLAYCGSYVPARAAKLGPIDRIFTRIGSADDLSTGKSTFMVEMTETSQILHHATNQSLVLMDEVGRGTSTYDGLSLAWACVVDLTKRVKCLCLFATHYFELTELGSEPGIDNYHVTAQELNGNLILLHKVQQGPASQSHGLQVAKLAGIPANVIKEAQKRLRILEKQQQQHLQTSVQSDLFATLDSEVTPSTQVIEKVIEVEVSSPALDLLKQIEVDNLTPRQALEQLYELKAALNS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: AROC_BRUAB
Sequence: MSHNSFGHLFRVTTWGESHGLALGCVVDGCPPGITFTEAEIQSFLDKRKPGQSKYTTQRREPDQVRVLSGVLLGEDGVTMTTTGTPISMMIENTDQRSKDYGEIARQYRPGHADYAYDVKYGIRDYRGGGRSSARETAARVAAGAIARKVVPGLEVRGALVSIGAHDIDRSRWNWAEVDNNPFFTPDAGSVEVFADYLDGIRKNGSSVGAIIEIVAEGVPAGIGAPIYGKLDQDIASYLMSINAVKGVEIGNGFEAARLTGEENADEMRMGNDGKPIFLSNHAGGVLGGIATGAPVVARFAVKPTSSILTPRRSIDKDGNEVDVMTRGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGRV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CHEB_BORBR
Sequence: MKKIKVLCVDDSALVRGLMTEIINSHPDMEVVATAPDPLVARELIKKHNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTERGGEITLRALELGAIDFVTKPKLGIRDGLIEYSEVIADKIRAASRARLRAPAPAGHAAPLRLRSPFASSEKLVIVGASTGGTEAIREVLQPLPADSPAILITQHMPAGFTRSFAQRLDALCAVTVREASDGERVLPGHVYLAPGGETHMRLGRSGANYVIGLQASEPVNRHRPSVDVLFHSAAEAAGGNAIGVILTGMGKDGAAGLLAMKRAGARTMAQDEASCVVFGMPREAIALGAADEVVPLADISERILTRLGDRGHRV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SALPK
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_PROM4
Sequence: MNLPDYSPNNSSLQWERFSELLWHNEELGLWVDISRMNVNEHELKELKPIFQKAFEAMNSLEKGSMANIDEERMVGHYWLRNPDLAPSRDISKLIANQISQIEQFTTSILSGDIRSDAGELFTDVLWIGIGGSGLGPLLLIESLQELNKGLKFHFLDNVDPIGIDKKLELLQSKLSTTLFVVVSKSGGTPEPQIAMDQARHVVETNGKNWPTRSVAITMCNSLLDNKAKQENWLKTFDLPDWVGGRTSITGAVGLLPLGLIDSDLKSFLLGASKMDELTRNNELLDNPAALMAMAWYSSGSAKGLKDMVVLPYRDSLEVFSRYLQQLVMESLGKKNDREGNIVFQGLSVYGNKGSTDQHAYVQQLRDGINNFFVTFIEVLTNNESPCLNNKLPGDYLSGFMQGTRLALSDSNRQSLTITLKTFDPLSLGALIALFERTVGLYAELININAYHQPGVEAGKKAAADILNLQLQIEDILSDYSNYSIEQISTRLSSSNSESIYFILRNLVFNNKYSAKGSWKNPSSLIFKREKL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHS2_YEAST
Sequence: MSEFLNENPDILEENQLPTRKEDSTKDLLLGGFSNEATLERRSLLLKIDHSLKSQVLQDIEVLDKLLSIRIPPELTSDEDSLPAESEDESVAGGGKEEEEPDLIDAQEIYDLIAHISDPEHPLSLGQLSVVNLEDIDVHDSGNQNEMAEVVIKITPTITHCSLATLIGLGIRVRLERSLPPRFRITILLKKGTHDSENQVNKQLNDKERVAAACENEQLLGVVSKMLVTCK
What is the function of this protein?
May play a role in chromosome segregation through establishment of sister chromatid cohesion.
What are the official names of this protein?
MIP18 family protein YHR122W.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
Protein: RS16_ENTFA
Sequence: MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLKDPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMKKHHEAKNVKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PAG15_RAT
Sequence: MDRHLCICREIQLRSGLLFPFLLLMMLADLALPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKRTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRTTQFPDGVDVRVPGFGETFSLEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALQEMIEEMYQMYGGPVVLVAHSMGNMYMLYFLQRQPQAWKDKYIQAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNHTWSHEKVFVYTPTANYTLRDYHRFFQDIGFEDGWFMRQDTQGLVEALVPPGVELHCLYGTGVPTPNSFYYENFPDRDPKICFGDGDGTVNLESVLQCQAWQSRQEHKVSLQELPGSEHIEMLANATTLAYLKRVLLEEP
What is the function of this protein?
Has dual calcium-independent phospholipase and O-acyltransferase activities with a potential role in glycerophospholipid homeostasis and remodeling of acyl groups of lipophilic alcohols present in acidic cellular compartments (PubMed:15294901).  Catalyzes hydrolysis of the ester bond of the fatty acyl group attached at sn-1 or sn-2 position of phospholipids (phospholipase A1 or A2 activity) and transfer it to the hydroxyl group at the first carbon of lipophilic alcohols (O-acyltransferase activity) (PubMed:15294901).  Among preferred fatty acyl donors are phosphatidylcholines, phosphatidylethanolamines, phosphatidylglycerols and phosphatidylserines.  Favors sn-2 over sn-1 deacylation of unsaturated fatty acyl groups of phosphatidylcholines and phosphatidylethanolamines (By similarity).  Among preferred fatty acyl acceptors are natural lipophilic alcohols including short-chain ceramide N-acetyl-sphingosine (C2 ceramide), alkylacylglycerols, monoacylglycerols, and acylethanolamides such as anandamide and oleoylethanolamide (By similarity).  Selectively hydrolyzes the sn-1 fatty acyl group of truncated oxidized phospholipids and may play a role in detoxification of reactive oxidized phospholipids during oxidative stress.  Required for normal phospholipid degradation in alveolar macrophages with potential implications in pulmonary surfactant clearance (By similarity).  At neutral pH, hydrolyzes the sn-1 fatty acyl group of the lysophosphatidylcholines (By similarity).
What are the official names of this protein?
Phospholipase A2 group XV, 1-O-acylceramide synthase, ACS, LCAT-like lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal phospholipase A and acyltransferase, Lysosomal phospholipase A2, LPLA2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Membrane; Peripheral membrane protein.
Protein: KITH_VAR67
Sequence: MNGGHIQLIIGPMFSGKSTELIRRVRRYQIAQYKCVTIKYSNDNRYGTGLWTHDKNNFEALEATKLCDVLEAITDFSVIGIDEGQFFPDIVEFCERMANEGKIVIVAALDGTFQRKPFNNILDLIPLSEMVVKLTAVCMKCFKEASFSKRLGTETKIEIIGGIDMYQSVCRKCYIDS
What is the function of this protein?
Phosphorylates thymidine and thymidine analogs, such as azidothymidine (AZT).  Part of the salvage pathway for pyrimidine deoxyribonucleotide synthesis.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: CGL_MACFA
Sequence: MQEKDASSQGFLPHFQHFATQAIHVGQEPEQWTSRAVVPLISLSTTFKQAAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPVLKMIDIEACAHIVHKRGDIILVVDNTFMSPYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNCERLHNRLRFLQNSLGAVPSPLDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPGVEKVIYPGLPSHPQHELAKRQCTGCTGMITFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLVELPAIMTHASVPKNDRDVLGISDTLIRLSVGLEDEKDLLEDLDQALKAAHPPSGSHD
What is the function of this protein?
Catalyzes the last step in the trans-sulfuration pathway from L-methionine to L-cysteine in a pyridoxal-5'-phosphate (PLP)-dependent manner, which consists on cleaving the L,L-cystathionine molecule into L-cysteine, ammonia and 2-oxobutanoate.  Part of the L-cysteine derived from the trans-sulfuration pathway is utilized for biosynthesis of the ubiquitous antioxidant glutathione.  Besides its role in the conversion of L-cystathionine into L-cysteine, it utilizes L-cysteine and L-homocysteine as substrates (at much lower rates than L,L-cystathionine) to produce hydrogen sulfide (H2S).  In vitro, it converts two L-cysteine molecules into lanthionine and H2S, and two L-homocysteine molecules to homolanthionine and H2S, which can be particularly relevant under conditions of severe hyperhomocysteinemia.  Lanthionine and homolanthionine are structural homologs of L,L-cystathionine that differ by the absence or presence of an extra methylene group, respectively.  Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.  By generating the gasotransmitter H2S, it participates in a number of physiological processes such as vasodilation, bone protection, and inflammation (By similarity).  Plays an essential role in myogenesis by contributing to the biogenesis of H2S in skeletal muscle tissue (By similarity).  Can also accept homoserine as substrate (By similarity).  Catalyzes the elimination of selenocystathionine (which can be derived from the diet) to yield selenocysteine, ammonia and 2-oxobutanoate (By similarity).
What are the official names of this protein?
Cystathionine gamma-lyase, CGL, CSE, Cysteine desulfhydrase, Cysteine-protein sulfhydrase, Gamma-cystathionase, Homocysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSP1_ARATH
Sequence: MASEDQSAARSTGKVNWFNASKGYGFITPDDGSVELFVHQSSIVSEGYRSLTVGDAVEFAITQGSDGKTKAVNVTAPGGGSLKKENNSRGNGARRGGGGSGCYNCGELGHISKDCGIGGGGGGGERRSRGGEGCYNCGDTGHFARDCTSAGNGDQRGATKGGNDGCYTCGDVGHVARDCTQKSVGNGDQRGAVKGGNDGCYTCGDVGHFARDCTQKVAAGNVRSGGGGSGTCYSCGGVGHIARDCATKRQPSRGCYQCGGSGHLARDCDQRGSGGGGNDNACYKCGKEGHFARECSSVA
What is the function of this protein?
Chaperone that binds to RNA, single- (ssDNA) and double-stranded (dsDNA) DNA, and unwinds nucleic acid duplex.  Exhibits a DNA melting activity.  May be involved in cold resistance.  Prevents seed germination under dehydration or salt stress conditions.
What are the official names of this protein?
Cold shock protein 1, AtCSP1, Cold shock domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the cold shock protein (CSP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PDXH_SALAI
Sequence: MDVTGDTVPPANLRNEYAADLGLTESNLAGDWYTQFDRWFTEVVAAGLPEPNAMVLGTADRAGRPSARTVLLKGYDPDGFVLFTNYGSHKGTELAANPYASLVFPWFMLQRQVVVTGRVDRLDRAETEAYFASRPRGSQLGAWASEQSRVLPNRSALDDAYRAMAERYADGVPIPAPPNWGGFRLRPDGVEFWQGQASRLHDRLRFRSTDGGDWVVERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: DPOL_BPT7
Sequence: MIVSDIEANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEVARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHSNLKDTDMGLLRSGKLPGKRFGSHALEAWGYRLGEMKGEYKDDFKRMLEEQGEEYVDGMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTDVGYTTFWSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARRSELLRKLTETFGSWYQPKGGTEMFCHPRTGKPLPKYPRIKTPKVGGIFKKPKNKAQREGREPCELDTREYVAGAPYTPVEHVVFNPSSRDHIQKKLQEAGWVPTKYTDKGAPVVDDEVLEGVRVDDPEKQAAIDLIKEYLMIQKRIGQSAEGDKAWLRYVAEDGKIHGSVNPNGAVTGRATHAFPNLAQIPGVRSPYGEQCRAAFGAEHHLDGITGKPWVQAGIDASGLELRCLAHFMARFDNGEYAHEILNGDIHTKNQIAAELPTRDNAKTFIYGFLYGAGDEKIGQIVGAGKERGKELKKKFLENTPAIAALRESIQQTLVESSQWVAGEQQVKWKRRWIKGLDGRKVHVRSPHAALNTLLQSAGALICKLWIIKTEEMLVEKGLKHGWDGDFAYMAWVHDEIQVGCRTEEIAQVVIETAQEAMRWVGDHWNFRCLLDTEGKMGPNWAICH
What is the function of this protein?
Replicates viral genomic DNA.  This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'-5' direction (By similarity).  Non-processive DNA polymerase that achieves processivity by binding to host thioredoxin (TrxA).  This interaction increases the rate of dNTP incorporation to yield a processivity of approximately 800 nucleotides (nt) per binding event.  Interacts with DNA helicase gp4 to coordinate nucleotide polymerization with unwinding of the DNA.  The leading strand is synthesized continuously while synthesis of the lagging strand requires the synthesis of oligoribonucleotides by the primase domain of gp4.
What are the official names of this protein?
DNA-directed DNA polymerase, Gene product 5, Gp5.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: SYR_FRASN
Sequence: MTPAELADTIVAAVRAAVANGDLEVAVPDSVTVERPRQPEHGDYASPVALQLAKAARRRPREVAELLAARLRAEAGVAEVEVAGPGFLNIRLAGAALGGIARRIVRDGESYGRAAVSQGVRVNLEFVSANPTGPVTLASARWAAVGDALSRVFAAAGYEVGTEYYVNDAGVQVERFGASVLAALRGQPAPADGYQGAYVAEIAAKVLAANPALEQLLAASGGEQDSGAEQDKALAVCARDGVELMLAEIRATLSGFGVEYDLWKSERSLHEAGELIAAIDELRTQGHVYEAGGAVWLRTTDFGDDKDRALIKSDGRPTYFCADAAYYRDKRRRGFDRLCYLLGADHHGYIGRLKAISACFGDDPDHNLDVLIGQMVTLSRGGVAVKMSKRAGNFLTLHDLVDAVGVDAARYSLVRASMDSALDLDLDAIARQTNDNPVFYVQYAHARISSLIRNAAALGLATSADPAFDVDGVDVSLLTHPREVDLLGALGELPRVVESAAELRAPHRIARYLEELAGTYHRFYDSCRVLPQGDEEPTAITAARLLLAEATRTVLANGLRLLGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_LACAC
Sequence: MSIKAEEISSLIKQQLEHYDDKLDINEVGVVTYVGDGIARAHGLDDVLSGELLKFDNGSFGIAQNLESNDVGIIILGQFDNIREGDRVQRTGRIMEVPVGDALIGRVVNPLGQPVDGLGEIKSDKTRPIEAKAPGVMDRQSVNQPLQTGIKAIDALVPIGRGQRELIIGDRKTGKTSLAIDTILNQKGQDVICIYVAIGQKESTVRTQVETLKRFGAMDYTIVVEAGPSEPAPMLYIAPYAGTAMGEEFMYNGKDVLIVFDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKLSDKLGGGSLTALPIIQTEAGDISAYIPTNVISITDGQIFLQSDLFFAGTRPAIDAGNSVSRVGGNAQIKAMKKVAGTLRTDLTAYRELESFAQFGSDLDQATQAKLNRGQRTVEVLKQPLHDPIPVEKQVLILYALTHGYLDAIPVEDISRFQNELFDNFDSSHADLLKTIRETGKLPDDKELSAAIEEFSESFTPSEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COPT1_ARATH
Sequence: MDHDHMHGMPRPSSSSSSSPSSMMNNGSMNEGGGHHHMKMMMHMTFFWGKNTEVLFSGWPGTSSGMYALCLIFVFFLAVLTEWLAHSSLLRGSTGDSANRAAGLIQTAVYTLRIGLAYLVMLAVMSFNAGVFLVALAGHAVGFMLFGSQTFRNTSDDRKTNYVPPSGCAC
What is the function of this protein?
Copper transporter involved in copper acquisition and transport in leaves.  Required for copper homeostasis and normal plant growth and development.
What are the official names of this protein?
Copper transporter 1, AtCOPT1.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: THI4_COPC7
Sequence: MAPALTLEKPVETNAFPRKAASVETSENYEGNYKFAPIEEAQVSRAMIKRYFNTMYDRAISDVVIVGAGSAGLSCAYSLATQRPDLKITIVEAGVAPGGGAWLGGQLMTPMVIRKPADAFLRELGVPYEDEGNFVVVKHAALFTSTLLSKVLAKPNVVMMNATAVEDLIVHEDFAGQQRVAGVVTNWTLVALNHDTQSCMDPNTITAPVIVSATGHDGPMGAFSAKRLVSTGLLKELGNMRGLDMNRAEPAIVNGTREVVPGLILTGMELSEHDGSNRMGPTFGAMIGSGHKAAHEAIRILDRHKVVNGKVVA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HLYT_GRIHO
Sequence: FELPSIPFPSPGSDEILFVVRDTTFNTKEPVNVKVSDFWTNRNVKRKPYEDVYGQSVFTTSGSKWLTSYMTVSINNKDYTMAAVSGYKDGFSSVFVKSGQIQLQHYYNSVADFVGGDENSIPSKTYLDETPSYFVNVEAYESGSGNILVMCISNKESYFECEEQQ
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Hemolysin, heat labile.
What is the protein family that this protein belongs to?
Belongs to the TDH hemolysin family.
Protein: PROQ_VIBCM
Sequence: MENTEKLKNSKEVIAYIAECFPNCFTLEGEAKPLKIGIFQDLADRLNDDPKVSKTQLRAALRQYTSSWRYLHGVKPGATRVDLDGNPCGELEEQHVEHAQAALAESKARVEARRKEQVKKVREEAKANKPKAKKPQQARRPQNAPKVEKKPVETRALAASELNVGNQVNVNMGKGNMAATIVEVNKEDVRVQLANGLQMVVKAEHLRA
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYCP_MAGML
Sequence: QQSKPEDLLKLRQGLMQTLKSQWVPIAGFAAGKADLPADAAQRAENMAMVAKLAPIGWAKGTEALPNGETKPEAFGSKSAEFLEGWKALATESTKLAAAAKAGPDALKAQAAATGKVCKACHEEFKQD
What is the function of this protein?
Cytochrome c' is the most widely occurring bacterial c-type cytochrome.  Cytochromes c' are high-spin proteins and the heme has no sixth ligand.  Their exact function is not known.
What are the official names of this protein?
Cytochrome c'.
Protein: O164_CONVC
Sequence: MKLTCVMIVAVLFLTANTFVTAVPHSSNVLENLYLKARHEMENPEASKLNTRYDCEPPGNFCGMIKVGPPCCSGWCFFACA
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels.  Act on high voltage-activated (HVA) calcium currents in molluscan neurons (By similarity).
What are the official names of this protein?
Omega-conotoxin-like Vc6.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1234_STAMF
Sequence: MKLFIVLVAGMPGAGKSIVSKAARDLGLPVYNMGDVIRMETSRLYGIITPETMRETSRRVRKLYGEDYVARKTIEQIKEKRGVIVVDGVRSLVEVEVFKKYAETVILAVHASPKTRFERIRKRNRPGDPDNWEDFVKRDLTELQFGLGNVIALADYMIVNEGSIEEAYRGAYNILKKLVEKNAKDNSDS
What are the official names of this protein?
UPF0200 protein Smar_1234.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: RS10_PARXL
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.