PharMolix/UniProtQA huggingface dataset:
Protein: MFGM_BOVIN
Sequence: MPCPRLLAALFCSSGLFAASGDFCDSSLCLHGGTCLLNEDRTPPFYCLCPEGFTGLLCNETEHGPCFPNPCHNDAECQVTDDSHRGDVFIQYICKCPLGYVGIHCETTCTSPLGMQTGAIADSQISASSMHLGFMGLQRWAPELARLHQTGIVNAWTSGNYDKNPWIQVNLMRKMWVTGVVTQGASRAGSAEYLKTFKVAYSTDGRQFQFIQVAGRSGDKIFIGNVNNSGLKINLFDTPLETQYVRLVPIICHRGCTLRFELLGCELNGCTEPLGLKDNTIPNKQITASSYYKTWGLSAFSWFPYYARLDNQGKFNAWTAQTNSASEWLQIDLGSQKRVTGIITQGARDFGHIQYVAAYRVAYGDDGVTWTEYKDPGASESKIFPGNMDNNSHKKNIFETPFQARFVRIQPVAWHNRITLRVELLGC
What is the function of this protein?
Contributes to phagocytic removal of apoptotic cells in many tissues.  Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.  Promotes VEGF-dependent neovascularization (By similarity).  Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.  Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.  Zona pellucida-binding protein which may play a role in gamete interaction.
What are the official names of this protein?
Lactadherin, BP47, Components 15/16, MFGM, MGP57/53, Milk fat globule-EGF factor 8, MFG-E8, PAS-6/PAS-7 glycoprotein, SED1, Sperm surface protein SP47.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein. Note=Located in the acrosomal region of zona-pellucida bound sperm.
Protein: K1A_STIGI
Sequence: MKFQVIAAVLLIEFCLCVVVTARMELQDVEDVENGFQKRRSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC
What is the function of this protein?
Inhibits voltage-gated potassium channels (Kv) with higher potency for Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-stichotoxin-Sgt4a, Kappa-SHTX-Sgt4a, Kappa1.3-stichotoxin-Sg1a, Kappa1.3-SHTX-Sg1a, Potassium channel peptide toxin sg-k, SgK.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1a subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: GSH1_ECOLI
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: AAEA_ECOHS
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPVDGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NUOB_XANAC
Sequence: MGVIQTLDSLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGASRLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQKKIWRTQTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PIMT_BURP0
Sequence: MSGERAKRFPLALEDLKREPRKPEGRVAERQAAGDAARQRLTAAAAVPAAASPIVPERRAPHGGVFAAKPARAKQHAPAAPGAAKRAPQGGAKQGDRSAAPNVALSGALALTSERVRERMVERLRANGVADPRVLAAMSAVPRHMFVDPGLAAQAYEDAALPIGHQQTISKPSVVARMIELAAAGRALERVLEIGTGCGYQAAVLSRVARDVYSIERVKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPAAAPFDAIVIAAAGLDVPRALLEQLAIGGRLVAPVGEQAGEQVLTLVERVAPAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLCD1_RAT
Sequence: MPLLLHPAWPLLLGATLTFRALRRVLCRLPLPAHVQTDPLRTWRWHNLLVSFTHSIVSGIWALLCIWQTPEMLVEIETAWSVCGYLLVCFSAGYFIHDTVDIVVSRQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDILLYKVNKYVNLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLSILLMLDVMILIYFSRLLRSDFCPERAPSRQQKDKFLTE
What is the function of this protein?
Regulates the composition and fluidity of the plasma membrane (By similarity).  Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity).  Does not appear to have any effect on LCPUFA synthesis (By similarity).
What are the official names of this protein?
TLC domain-containing protein 1, Calfacilitin.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGB_CUTAK
Sequence: MAHDEFGGLTGWDLEGFHSGGDTEVWKRLGSHVVTIDDDERGPITGTRFAVWAPNAQAVEVISDFNWWTGDRMRLIPGSGVWGTFVEGVDEGTLYKFRIQDQWGTWHEKVDPMARYSEQAPQNASIVTETHYEWNDDEWIARREASRAHAEPMSVYEVHLGGWRHGLSYRELADQLVSYVTWQGYTHVEFMPLAEHPFAPSWGYQVTGYFSPTSRYGSPDDLRYLIDKLHQAGIGVIMDWVPGHFPKDDWALGRFDGTALYEHADPRQGEHKDWGTYIFNYGRNEVKSFLVSSALYWISEFHADGLRVDAVASMLYLDYSREEGQWVPNKYGGRENLEAIDFLRYVNSHLYSRHPGILMIAEESTSFPGVTKPVDDGGLGFGFKWNMGWMNDSLRYLELNPFHRQYHHGEMTFAMVYQYSENFILPISHDEVVHGKGSMITKIPGDDWQQFASLRAFYSYMWSFPGKQLVFMGQEFGQRHEFDESVSLEWFVADLWGHGGLKRLFRDLNKIYKENPALWQLDSDPRGFEWINADDAGNNLFSWLRRSDDGSTIACFTNFSPNPQTDYRIDLPMEGVWTEILNTDSLEYDGTGEFGNLGQIVAAPLPAPDRLRAVATVCVPPMGSVWLRHNPSATAALPGDPGVQ
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: DCL2_NEUCR
Sequence: MDQDPRKDNPVEMDVDRDDSSQDPDDNESFKSALDEPLDLKELYQDALEKPSEEPSEELNDQVSTPAALTARAYQLEMFEASLKQNIIVALFSDRVMVADGHWQWQDSGRIWFLTPTVALARQQHRVLQSQIPSVKAIMLCGQDGVDSWSEQAVWDAVLLNVRIVVSTYQILFDANAHSFVRLDSLSLIVIDEAHNCSGSHPIARLMTEAYLPAKKAGLPVPSILGLTASPLKSNNLADIEKLEQVLDAVCRTPTIHREELLAHVNRPEMLVVSYGDSGTDPTPTDLMTRFLEAYHRLDISKDPDVLLLKAQRTERAREKLRQMITKKDTLAQKELRGVYNRALLVRREIGPWAADYYLTRTVSHMLAELERGEPPAQHRYIGEALRSIPIPAISKEPIQLSPKVQTLLKVLASHQQDPVGIVFVKERVMVSIVTHIISTHPLTKDRYRTASMIGTASVPGKARNHMDMTKKEDMTSLEGFRLGRFNLLVATSVLEEGIDVPICNLVICFDEPSNIKSFIQRRGRAREVSSTLYLMVQNASSESATDWHNLERLMKERYEDEMRQNAELELLDDPRIGSYPVLEVESTGARMTIRDARSHLNHFCAKVSSRSRYLQKEPYFVIRQVNPDPASPGRRTLLQATVHLPASLAPDLRRHESLWTWTSEKLAIMDASFQAYKALYNAGLVNENLLPTKVSDFLADLGDDPGHIWVKTQFDPWPEVAYAWQESSSLYSRRLTVLVPGVENPLEFEFILPVPVPYMAPLKLWWNATSALTLITSPEMQEFRKQEGTSAGPDHSYALLAMAFAHRFPIQGRQYPIRLVSTRRKLDVDGIAALEFDPRLYESSPQPPLVRLVDGRNMPYFVTKILPSKPPVELISKPSTDHADLPENVPYVVCKPIGKAVGQFIPLDAAQDQDSWTPKNGKLYRKVLPSTQIRMDNFPAVFAQVGAVIPAFTRAVEMSLVAADLMYNRLGCLQLDNLPLITTALISSGSRGPTNYERLEFIGDTILKFCACLTASALFPNHHERLLSQWKDKLVNNVRLCRASRDFGLDEYIINSAASKKWRPKFVEDYMDEMKSPISAETRQMSSKMVADVVESLIGAAYMCGGMSKALECVALLLPTPKSSQFKWQEIELSRTQLFEFAPKDAILSKQLEPLEKAMDYTFNKKSLLIEAMTHPSCAGLGTNESCYERLEFLGDAILDVIVVKRLMAETGPNELAHNDMHEHLSSVVTADIMAFLAMEWVIMQTDINEIDPTNLDALGLLPSSQSRITPASLVSNKEDWPFWRFMRHNSPQVGATQTATIERYLTLRDEIRDAIWKHNTLPWALLARMGPQKFYSDIVESLIGAVWVDSGSWKACEDVLTQMGLLPLLDHLLETKAHVMHPNVELQILAPPNKRATRTEFVIISNKRGIISSGTEFLDEPSAVDDGLVSVEPYDDTPEHDEVFSCKLFVGGKQVADVTGAATKEEARVRAAEKGCLVIKAERKVWNEAKAAAKEDKGHNTENGDANADNGQSGEKEEVPDCRDADGDTVMN
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons.  Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume.
What are the official names of this protein?
Dicer-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: NUSB_MYCTU
Sequence: MSDRKPVRGRHQARKRAVALLFEAEVRGISAAEVVDTRAALAEAKPDIARLHPYTAAVARGVSEHAAHIDDLITAHLRGWTLDRLPAVDRAILRVSVWELLHAADVPEPVVVDEAVQLAKELSTDDSPGFVNGVLGQVMLVTPQLRAAAQAVRGGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MDTP_ECO57
Sequence: MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKLADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDAGSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGVHRSAVTAAIGAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAVKAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPEIKPVALPRVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAFFGLDSIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVLNAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPVLAEEMSLLMLDSRRVIQSIQLMKSLGSGYQAAPVVEKK
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Multidrug resistance outer membrane protein MdtP.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: KV5A8_MOUSE
Sequence: MDMRAPAQVFGFLLLWFPGARCDIQMTQSPSSLSASLGERVSLTCRASQDIHGYLNLFQQKPGETIKHLIYETSNLDSGVPKRFSGSRSGSDYSLIIGSLESEDFADYYCLQYASSP
What are the official names of this protein?
Ig kappa chain V-V region MOPC 173B.
Protein: FABH_STAAR
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP2AB_BACVZ
Sequence: MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENCDGKVYISVTLEDHVVYLTIRDEGIGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDVTIDSSPEMGTTIRLTKHLSKSKALCN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: REND_ECOLI
Sequence: MARAGILVVDGKVWRTVYYRFATREEWEGKVSTNLIFKECRQSAAMKRVLRVYKRTSMGTQ
What are the official names of this protein?
Putative protein RenD, Putative defective protein Ren from DLP12 prophage.
Protein: RL35_RHOPS
Sequence: MPKLKTKSGAKKRFKVTATGKVMSAQRGKRHGMIKRTKKQIRQLRGTRVIFKTDGDNIKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y1035_RHIL3
Sequence: MSLLTLKNRRERGFFDGQFLIAMPGMEDRNFARTVIYICAHSDAGAMGFVINRPQSLTFTDVLLHLDMIKQEDSIVLPKRAREFPIQTGGPVESGRGFVLHSDDYSSDSSIPVSDDICLTATLDIVRAISKGDGPTRATMLLGYSSWAAGQLESEVVNNGWLTCPANEELIFDRSLDDKYERALAGMGVTAAMLSAEAGHA
What are the official names of this protein?
UPF0301 protein RL1035.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: HSLV_GLAP5
Sequence: MTTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRLYKDKVVTGFAGSTADAFILRDLFEKKLELHQGHLVKSAVELAKEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEFDVLAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDIDIYSNHNHVIEEV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_BDV1
Sequence: MPPKRRLVDDADAMEDQDLYEPPASLPKLPGKFLQYTVGGSDPHPGIGHEKDIRQNAVALLDQSRRDMFHTVTPSLVFLCLLIPGLHAAFVHGGVPRESYLSTPVTRGEQTVVKTAKFYGEKTTQRDLTELEISSIFSHCCSLLIGVVIGSSSKIKAGAEQIKKRFKTMMAALNRPSHGETATLLQMFNPHEAIDWINGQPWVGSFVLSLLTTDFESPGKEFMDQIKLVASYAQMTTYTTIKEYLAECMDATLTIPVVAYEIRDFLEVSAKLKEEHADLFPFLGAIRHPDAIKLAPRSFPNLASAAFYWSKKENPTMAGYRASTIQPGASVKETQLARYRRREISRGEDGAELSGEISAIMRMIGVTGLN
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Targets viral NC to the nucleus.  Could be involved in the transport of nucleoprotein particles from the nucleus to the cytoplasm.  The nuclear export signal is masked by the interaction with the P protein.
What are the official names of this protein?
Nucleoprotein, N protein, Nucleocapsid protein, p38, p40.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LIN54_DROME
Sequence: MDTSGGNLDSLDDTEPLPELSFEDFLEPTSEKSSQHMEIEALDSEEDNIGGEDLADPANDSLNTPQFKKNVVHILEDKRLNSSGLTVLKSHAIKMVTAGGTPPAKAQVTDVKILNKLKPIPSSTLKIGSTTIATKSTPGSITKTLGNLTQIRTKDGQVIFVQKSVPGTQSSTAVTGSPSGGIRRLVAPSGIQKAVLSKGVTMASTGLVKAAVPAKASTSVPGSAITLKGIQPLAGGTAKASTSSTTATTSPSLAQPNKIQVVRTADGKIIKINQAGPSLLVNAKQGTGTTVTPGGSAATSVKLSPSTGNVVLNKPVGQVVVRTETPVKTATGSVASASATPGKMLVQSGGKQILVSNKNIIKLSPNASATSSTTHTTGGQTPSTSSGLHAIQLPGKGGIQYVRVLNNNKSAAGTSATASIPKTVQTQKITVVRPPAATGVPATSTTTSAAAASPAAASKANLAMGNTNKIVMRSMGGSIVPLPSVQTLVSKRALGAISNASKPASAASSSATPSASQELPRKHRLTDLNVQLKQSASVSSEASDSSDAGPEAKKPRYVITMQQGSQKAASQPVQKLINRTANVQRVVSSSTSPSSNSTKKIYNYVQPTGSNGAKYMICNSGVPQSSTSAMRRGYTGYVENKTRRPPPISPQQHRFKQMGPQQQSKHQQLQAQAKQRIRQQQLPTEQSTPIKVEPKLPTLPPGVKANVPAKPLFEVLKPPATAAAAGAVDPLGGMTSRRKHCNCSKSQCLKLYCDCFANGEFCQDCTCKDCFNNLDYEVERERAIRSCLDRNPSAFKPKITAPNSGDMRLHNKGCNCKRSGCLKNYCECYEAKIPCSSICKCVGCRNMEDRPDVDMDSLDGLMGVEGQKKDKAKNKQLNENRANIYFTDDVIEATIMCMISRIVMHEKQNVAVEDMEREVMEEMGESLTQIIAFAKEKQETSQIDESKPSS
What is the function of this protein?
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context.  In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci.  During development, the complex represses transcription of developmentally controlled E2F target genes.
What are the official names of this protein?
Protein lin-54 homolog, Myb complex protein of 120 kDa.
What is the protein family that this protein belongs to?
Belongs to the lin-54 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU6M_PTESA
Sequence: MMTYIVFILSTVFVVGFVGFSSKPSPVYGGVGLIVSGGVGCGIIMNFSGSFLGLMVFLIYLGGMMVVFGYTAAMATELYPEVWVSNKVVFGAFVFGLFMEMLLVLYVLKEGSVGIAFEFSNLGDWVVYGVEDSGYFSKEAVGISSLYSYGMWLVVVTGWSLFIAVVVVMEVTRGG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLPK_LIMRD
Sequence: MSEQQYIMAIDQGTTSSRAIIFDHDGNKVAISQQEFPQYFPQPGWVEHDPLEIWDSVQSVISNVMIKSQIKPYKIAAIGITNQRETTVIWDRHTGKPIYNAIVWQSKQTSDIAEQLIKDGYKDMIHQKTGLVIDSYFAATKIKWILDHVPGAREKAAKGDLMFGTIDTWLLWNLSGRRVHATDVTNASRTMLFNIHTLDWDQDILDLLDIPQSLLPVVKPSSAIYGYTGDYHFYGVQIPIAGIAGDQQAALFGQAAYDKGSIKNTYGTGAFIVMNTGLKPTLSDNGLLTTIAYGLDGQTHYALEGSIFVAGSAVQWLRDGLKMFDKASESEQMAVDAKTTGGVYVVPAFTGLGAPYWDQEVRGAMFGLTRGTERGHIIRATLEAIAYQTKDVVDTMVKDTQLPLTALTVNGGASRNNFMMQFQADILQTPIKRAAMEETTALGAAFLAGLAVDFWEDQDELRKLSRIGDQFDPQMDPQKAADLYRGWQRAIAAAQFYGKD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL33_PAEAT
Sequence: MAKDKDVRPIIKLKSTAGTGYTYVTRKNRRNDPDRLVLKKYDPKIRQHVEFREER
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PDE8_DROME
Sequence: MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSDGNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTGTSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (By similarity).  Involved in the positive regulation of MAP kinase signaling and in inhibiting oxidative stress-induced cell death (PubMed:23509299).
What are the official names of this protein?
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8, Phosphodiesterase 8.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
Protein: MECR1_CAEEL
Sequence: MLKVLSLRSALQRAASTRQLVYEGYRNPPEAIQLKTVTIADKPSADQVLVQWIAAPINPADLNQIQGVYPVKPALPAVGGNEGFGKVISVGSNVSSIKVGDHVIPDRSGLGTWRELGLHQENDLFPIDNTLSMEYAATFQVNPPTAYRMLKDFIDLKKGDTVAQNGANSAVGKHVIQICRILGIKTVNVVRSRDNLEELVKELKDLGADEVITQEELYSRKKKFPGVKLALNCVGGRSSLFLASLLDHGGCMVTYGGMSKQPVDCPTGPLIFKDISLRGFWMSRWYDIQKSPEKRHEMYQELAGWMKSGEIKKQEIVKNRLEDHAKALDTALSKFDKKQFFVLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II).  Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase, mitochondrial, 2-enoyl thioester reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARK1_SCHPO
Sequence: MSDSKLADSLNCLSVSTPSTTANPGRQQLLRLAVSNQRQVNNVSLANGKENKRTSNSKFNSSLRKIEEPIAGVPSSAGPQWREFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKRMSLEQVMRHPWIVKYKDSWTRKSSESS
What is the function of this protein?
Required for the spindle checkpoint attachment response during spindle formation, kinetochore microtubule interactions and chromosome segregation during anaphase.  Ark1 activity depends upon cut17 function and phosphorylation.  Ark1 with bir1 is required for full-scale association with kinetochores and formation of a complex with mad3.  Ark1 is also required for phosphorylation of histone H3 that accompanies chromosome condensation and condensin recruitment to mitotic chromatin.  Ark1 with pic1 is required for the execution of cytokinesis.
What are the official names of this protein?
Serine/threonine-protein kinase ark1, Aurora-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Associates with the elongating spindle during anaphase.