PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_FRATF
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL2_CHLT3
Sequence: MPVRILKPRTPGTRFFSYPSFEEITTDKPEKSLLVPNKSTGGRNNNGRVTSRHMGGGHKRYYRIIDFKRNKDGIPAKVATIEYDPNRTARIALLSYADGEKRYILAPNGIKVGDLIECGPEADIKVGNALPLKNIPVGIEVHNIEMRPGKGGQMARSAGSYAVLVAKEGDYATLKMPSGELRKVRVECKATVGVIGNLEHENLSLGKAGRSRWLGIRPQTRGMAMNPVDHPMGGGEGKSKSGGGRKHPKSPWGQKSKGLKTRKRKKASSKLIVRRRDSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HEM1_CAMHC
Sequence: MNYMSVSFTHKNTDIIVREKLSFANDVKKREILKLICSNKAIKECLVLSTCNRVEVLAYIDDFNYTSDYVIKAISKLSGVDFDELKERADIYEDDGAIHHLFSVASSLDSLVVGETQIVGQLKDAYNFAKNERKSGVMLDLAINSALKCAAVIRSKTDISKNPISVASVAVCMAREKIGDLGGTTAVVVGAGEMAELACKHLITHKAKVIIINRNIDHAKKLAESLGENASIAEFSNLGEFINKYALIFSATGANKPIITDLLAKPQNFKRYFFDIAVPRDIDITCDDLSEVYAVDDLEEIVRKNLLLREEQAQIAYSIVGRETTKFYKDLKTLSSTPIIKALRNSAKKVAETELKKAIKRGYLRHSDIDEARKLIHQVFKAFLHTPTVNLKNLDENAQNDINAIAEIFGIEEDFDKFCENSLENKNEI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BGLF_ASPTN
Sequence: MAPSSLKWTLLCALPWTLASPASYNVHHARDSDAQAFSPPYYPTPHGGWIADWAEAYEKASQLVRNMTLAEKVNLTTGTGMYMGPCAGQTGSVPRFGIPNLCMHDGPLGVRNTDHNTAFPPGITVGATFDKDLMRSRGVALGEEGRGKGVNVLLGPSVGPIGRKPRGGRNWEGFGADPSLQAIAGSLTIEGMQSTGLIACIKHFIANEQEMHRMSSVVTQGYSSNVDDRTLHELYLWPFAEGVRAGVGSLMAAYNDVNNSASSQNSKMLNDILKDELGFQGFVMSDWFGNYGGVSAALAGLDVSMPGDGAIPLLGDSYWGSELSRSILNGTVPVDRLNDMATRILASWYKMGQDQDYPLPNFSANTEDAEGPLYPGAVFSPKGVVNKFVNVQGDHNVTARAIARDAITLLKNNNNILPLHRNDSLKIFGTDAGTNPDGINSCSDKGCNKGVLTMGWGSGSSKLPYLVTPQEAIANISSHAEFHITDSFPSDVSAGPNDIAIVFINSDSGENYITVEGNPGDRTSAGLNAWHNGDDLVKAAAEKFRQVVVVYHTVGPVLMEEWIDLEPVKAVLVAHLPGQEAGWSLTDVLFGDYSPSGHLPYTIPRSESDYPDSVSLIQQPFGRIQDDYTEGLYIDYRHFAKAGITPRFPFGYGLSYTNFNFSRASISAQSSLDTAYPAPRSPKGSTPEYSTAIPPAAEAAWPKNFNRIWRYLYPYLDNPEGARANSSRKYPYPDGYSTVQKPGPRAGGGEGGNPALFDVAFSVQVQVTNTGARKGRAVAQLYVELPDSLGVDTPSRQLRQFEKTKILAPGESQVLTMEITRKDLSVWDVVAQDWKAPVNGEGVKMWIGESVADMRVLCTVGEGCSTL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase F, Beta-D-glucoside glucohydrolase F, Cellobiase F, Gentiobiase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBC12_ARATH
Sequence: MASKRISRELRDMQRHPPANCSAGPVAEEDIFHWQATIMGPHDSPYSGGVFTVSIDFSSDYPFKPPKVNFKTKVYHPNIDSKGSICLDILKEQWSPAPTTSKVLLSICSLLTDPNPNDPLVPEIAHLYKVDKSKYESTAQKWTQKYAMG
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Probable ubiquitin-conjugating enzyme E2 12, E2 ubiquitin-conjugating enzyme 12.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: TLC1_SOLTU
Sequence: MEGVLQTRGLLSLPSKPKIKAFYPLPQGGLRNRFNSLSSLKPNPLNGVSLSSNGFQKVQGFDTKPQLFGQKKRCFPICKAEAAAAAGAADGQPLFVEKEQPKFMGIELVTLKKIIPLGAMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLANVLSKEALFYTVILPFIAFFGAFGFVLYPLSNYFHPTAFADKLLNTLGPRFLGPIAILRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKRFYPLFGLGANVALIFSGRTVKYFSSLRSSLGPGVDGWAISLKGMMSIVVMMGGAICFFYWWVNRNVALPTRSKKKKVKPNMTTMESLKFLVSSKYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSSFMGDFSTATGIATFTMMLLSQWIFDKYGWGAAAKITPTVLLLTGVGFFSLLLFGAPLAPTLAKFGMTPLLAAVYVGAMQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILTFGSLASSTPYLGGVLLVIVLAWLGAAKSLDGQFTQLRQEEDLEKEMERASLKIPVVSQNENGNGPLSSESSLNPAGGDSTNASSEPSSPRSL
What are the official names of this protein?
Plastidic ATP/ADP-transporter.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc (TC 2.A.12.2) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RIMP_PROA2
Sequence: MVEDRLISGIEACVASFSREVSTGKESEIFLVDLAVKAAGRSVKIEVLVDSEQGIVISQCAALSRRIRDMIESDDELQEVYGEVFELMVSSPGLGGPIRHVRQYIRHTGRLLSVRYRDDAGSVHDVTGRLIEVDLAEGHEPFLVLEPVRSGRKKNGSLPPSRLKMMLDRIDKAVVQVEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_HAEIE
Sequence: MKKKKLLVMAGGTGGHVFPAIAVAQTLQKQEWDICWLGTKDRMEAQLVPKYDIPIRFIQISGLRGKGIKALFNAPFAIFRAVLQAKKIIQEEKPDAVLGMGGYVSGPAGVAAKLCGVPIILHEQNAIAGLTNKLLGKIASCVLQAFPTAFSNAEVVGNPVREDLFEMPNPDIRFSDREEKLRVLVVGGSQGARVLNHTLPKVVAQIADKLEVRHQVGKGAVEEVRQLYGENLEQVKITEFIDNMAEAYAWADVVICRSGALTVCEIAAVGAAAIFVPFQHKDRQQYLNAKYLSDVGAAKIIEQADLTPEILVNSLKNFTRENLLQMALKAKTMSMPNAAQRVAEVIKQYSN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: S5AEA_BACSU
Sequence: MTTKRKVILVTDGDVYAAKTIEYAASKVGGRCISQSKGNPSTRSGAELVKLIASAPYDPVFVMFDDSGLQGEGPGEAALTYVATHPSIEVLGVIAVASKTHQAEWTRVDVSIDRNGEITEYGVDKVGEREFDDHRMSGDTVYCLDKLDLPLIVGIGDIGKMGRKDDISKGSPITMKAVEFILERSGYHAGPQGRENSGLSESS
What are the official names of this protein?
Stage V sporulation protein AE.
Protein: PAGP_PHOAA
Sequence: MKFDLTTAYTLSIPLLASSGTVLATTADTSSKSSTMTAIHTSTGYNNHSDSLWATFNNNVALTWDAPNNEFYLPVITWHNRYTYDKEKTDKYNERPWGFGYGKYRYDKDNDWHSLYAMAFMDSHNRLEPIIGYGFQKMWIPGDLDGFRLGVGFTLSVTARHDYYYVPIPLPLPLFSVEYDQLSFQGTYIPGTYNNGNVFFAWLRWQW
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CCT1_ARATH
Sequence: MSNVIGDRTEDGLSTAAAASGSTAVQSSPPTDRPVRVYADGIYDLFHFGHARSLEQAKLAFPNNTYLLVGCCNDETTHKYKGRTVMTAEERYESLRHCKWVDEVIPDAPWVVNQEFLDKHQIDYVAHDSLPYADSSGAGKDVYEFVKKVGRFKETQRTEGISTSDIIMRIVKDYNQYVMRNLDRGYSREDLGVSFVKEKRLRVNMRLKKLQERVKEQQERVGEKIQTVKMLRNEWVENADRWVAGFLEIFEEGCHKMGTAIVDSIQERLMRQKSAERLENGQDDDTDDQFYEEYFDHDMGSDDDEDEKFYDEEEVKEEETEKTVMTDAKDNK
What is the function of this protein?
Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine.  Catalyzes the formation of CDP-choline.
What are the official names of this protein?
Choline-phosphate cytidylyltransferase 1, AtCCT1, CTP:phosphocholine cytidylyltransferase 1, Phosphorylcholine transferase 1.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
Protein: RPAB3_CAEEL
Sequence: MAGIIFDDMFKVKSVDPDGKKFDRVSRYFCDAESFKMELIIDINSQIYPLKQNDKVRLVLATTLREDGLADEGEYDPKAEYPRIKQYEYVMYGKVYRLEDDDTGTDGGKLAAYASFGGLLMRLKGEAINLHGFEVDMNLYLLMKKTDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerases I, II, and III subunit ABC3, RNA polymerase B subunit 8, RPB8, RPB17.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEXA_ACTPJ
Sequence: MSRKHLTARQQEIFDFVKHHIETTGMPPTRVEIAREIGFKSPNAAEEHLKALARKGYIEMLSGTSRGIRILVDNEETAANDDGLPLIGKVAAGTPIMAIEHVESHYPVNGAMFNPNADYLLKVNGNSMEKIGILDGDLLAVHKTNFARNGQVVVARVDDEVTVKRLEKKGDLIYLHPENDELQPIIVDPRIEYIEIEGIAVGVIRNNAWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL22_COREF
Sequence: MSDNITSARATARFVRVSPMKARRVIDLVRGKTVVEALSILKYAPQAASEPVAKVVASAAANAENNFGLDPRTLVISEAYADEGPTMRRFQPRAQGRAFQIRKRSSHITVVVESQKEGAN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SFSA_HAEIG
Sequence: MQLPALQSAKLIRRYKRFLADIELPTGDVMTIHCANTGAMTGCGEKGDTIWYSHSDSQTRKYPHSWELTQLANGQLCCINTHRSNQLVFEALQNKQIKELAMYDEIYPEVKYGEENSRIDFLLKGKGLPDCYVEVKSITLVKGNLGMFPDAVTTRGQKHVRELLAMKKQGHRAVVLFAGLHNGFDRFKIAEYIDPEYDRLLKEAMEQGVEAYAYAGQFEISNEIPTALSLTESVPYIK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: C556_AGRTC
Sequence: AGEVEKREGMMKQIGGSMGALAAISKGQKPYDAEAVKAAVTTISTNAKAFPDQFPPGSETGSAAAPAIWENFDDFKSKAAKLGADADKVLASLPADQAGVTAAMQTLGADCGACHQTYRLKK
What is the function of this protein?
Low-spin monoheme cytochrome c.
What are the official names of this protein?
Cytochrome c-556, Cytochrome c556.
Protein: 1A14_SOLLC
Sequence: MDLETSEISNYKSSVVLSKLASNEQHGENSPYFDGWKAYDNDPFHLVNNLNGVIQMGLAENQLSVDLIEEWIKRNPKASICTNDGIESFRRIANFQDYHGLPEFTNAIAKFMEKTRGGKVKFDAKRVVMAGGATGANETLILCLADPGDAFLVPTPYYPGFNRDLRWRSGVQLLPISCKSCNNFKITIEAIEEAYEKGQQANVKIKGLILTNPCNPLGTILDRDTLKKISTFTNEHNIHLVCDEIYAATVFNSPKFVSIAEIINEDNCINKDLVHIVSSLSKDLGFPGFRVGIVYSFNDDVVNCARKMSSFGLVSTQTQHLLAFMLSDDEFVEEFLIESAKRLRERYEKFTRGLEEIGIKCLESNAGVYCWMDLRSLLKEATLDAEMSLWKLIINEVKLNVSPGSSFNCSEVGWFRVCFANIDDQTMEIALARIRMFMDAYNNVNKNGVMKNKHNGRGTTYDLTPQMGSTMKMLLA
What is the function of this protein?
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase 4, ACC synthase 4, Le-ACS4, ACS-4, S-adenosyl-L-methionine methylthioadenosine-lyase 4.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: DRC9_CHLRE
Sequence: MVGIDTGGKIPPEIMRQATEKTAQLAPLEGGHIYSILKQTLEKLALVGQLQVDPKVQAHELTQSVGEEISRMITEQKKLESRFEELVALQHVLRHQPNKTKLMENQVASERQALQLLLSNCLNEIEVFGKVQPLVESVMAQQAAEQAMKETIEREKNTTAAVRQLRNDLREEKLDHEEKMKEKKKGLSTLKEQLKALKMDTAVSTRYLSKDLTAGNEHERRLQRTQLEDLLKDLGLVQQQIDIEKAVHATQAEFLRQIAAKMADDSSNWASRHDGDLAAREKELEMLKQQHARDLIELKKAEEKFKMEQALKKEREMKATEERERAEFEEMRETRRAQAAVIIQAWWRGHKVRMVMSGGGKKGAKKGGAKKKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337).
What are the official names of this protein?
Dynein regulatory complex protein 9, Flagellar associated protein 122.
What is the protein family that this protein belongs to?
Belongs to the DRC9 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: HMP_PHOLL
Sequence: MLDNQTIATVKSTIPLLSATGPKLTAHFYERMFKHNPELKNIFNMSHQLNGDQREALFNAICAYAANIDNLKVLLPAVEKIAHKHASLNIQPEHYQIVGTHLLATLNEMFQPGNEILDAWGKAYGVLADIFINREEQIYHSGELTDGGWRGLRPFRINRKEVKSEVICSFEFAPQDGGKVMDYKPGQYLSIYLQDDSFANREIRQYSLTAAPNGSSYRIAIKREPQGIVSNHMHDKMQEGDTVWLTAPRGDFFLDIKPETPVTLISAGVGLTPMMSMLYHLHQQNHNSPINWLHAAEHGGHHAFSHEVAAIAQAMPNFAGTIWYREPRDEDQQGIHYQHKGFMDLTVLNEALKTEGMHFYFCGPVAFMQYVAKQLLDMGIDKQFIHYECFGPHKVI
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: RGN_DANRE
Sequence: MSSIKVECVIKEKNEVGESPVWEEKDSSLLYVDITGQKVSRWSSLTKQIESMNTEKLVGCVVPRQAGGYVIAEGTRFAFVDWVKRSITAVAEVNEKPNTRFNDGKVDPAGRFFAGTMSMDMKPDVVDAALYNLQPDHSVVRHFDQVHLSNGLDWSLDHRVFYYIDSLAFMVEAFDYDIQTGGLSNRRTVYKMEKDEGIPDGMCIDTEGKLWVACFNGGRVLRIDPQTGKRLQTVKLPAERITSCCFGGKDYSDLYITSAYIGMDAEALAKQPEAGCTFKVTGLGVKGIPPYSYTG
What is the function of this protein?
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone.  Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis.  Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).  Calcium-binding protein.  Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
What are the official names of this protein?
Regucalcin, RC, Gluconolactonase, GNL.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STA5B_PIG
Sequence: MAVWIQAQQLQGDALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGTSPAGSLADAMSQKHLQINQTFEELRPVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLNPQERLSRETALQQKQVTLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQRAKSLLKNESTRNDCSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSSHLEDYSGMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVYSKYYTPVPCEPATAKAVDGYVKPQIKQVVPEFVSASSDSAGGNATYMDQAPSPAVCPQAHYSIYPQNPDPVLDNDGDFDLDDTMDVARRVEELLGRPMDSQWIPHAQS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  Binds to the GAS element and activates PRL-induced transcription.  Positively regulates hematopoietic/erythroid differentiation.
What are the official names of this protein?
Signal transducer and activator of transcription 5B.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: RLMN_THENN
Sequence: MKNLLDLSYDELVSEITSLGLERYRADQILDWVFDKKVNNFDEMTNLSKQHRALLKEHFTIPFLKLLEKRVSKIDGTTKFLWELEDGNTIESVMIFHPGRITACISTQVGCPVGCTFCATGMSGFVRNLTTGEIVSQILSMEKEEGKKIGNVVYMGMGEPLLNYENTIKSIRILNHKKMGNIGIRRITISTVGIPEKIIQLADEGLDVKLALSLHAPTNFKRDQLVPLNRKYSVEEILNAIKVYQMKTGKRVTIEYVLIRGVNDEISDAKKLAEILKGLKVFVNLIPVNPTVAGLSKPSRQRILAFKRILLENGIEAEIRQEKGSDIEAACGQLRLKRKVSSP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_METVS
Sequence: MAKIIKFNEEARKKLENGVDVLSNTVKVTLGPKGRNVVIEKSYGSPLITNDGVTIAKEIELEDPFENMGAQLIKEVATKANDVAGDGTTTATVLAQAMVKEGLKMITAGSNPVFVKRGIEKATKKAVSILETKSKKIAGNSEIAQVASISAGDEEIGNLIAKAMEKVGENGVITVEEAKSLETTLEVVEGMQFDKGYISSYLVTDPERMTAELDDPYILITDKKISNMKEILPVLEATARSSRPLLIIAEDIEGDVLTTLVVNKLRGTLNVVGVKAPYFGDKRIGALEDIAILTSSQVISKDKGMELEKVDISSLGSAKKVKVTKDNTLIIGGIGKEKDITSRISQIKTQISSTTSEYEKDSLKERLAKLSGGVAVIKVGSATETELKEKKLRIEDALNATKAAIEEGIVSGGGTVLIEILKEMESFELSGEERIGVNIVKKALTAPLKQIAENAGLEGSIVVEKVKNAESGIGFDAAKEEYVDMIKSGIIDPAKVTRSALQNSASVAALVLTTEAIIVDKPKKEESDTPNMPMMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH2_BACCZ
Sequence: MKKGINRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVGEHGDTELPVWSHATIGVQKLETILANNEQYKQEDLDKIFENVRDAAYHIIERKGATYYGIGMSLLRVTKAILNNENSVLTVSAYLEGQYGEKDAYVGVPAVINREGVREIVELELNEEEKAKFAHSVKVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYBA_CYPCA
Sequence: MSDNPVKEEVQQFDKKCLKKTNTAEKNTLPTKEDIDQEKKAAEGGK
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
What are the official names of this protein?
Thymosin beta-a.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: COX8B_SHEEP
Sequence: ITAKPAKTPT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8B, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver/heart, Cytochrome c oxidase subunit 8-1, Cytochrome c oxidase subunit 8H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: JAL1_ARATH
Sequence: MKIGPVGKHDARSTTIVNWDEGSHDGFISQIFLSHGVAGIMSIQFQFVMDGKLVLSDRHGPFSGNMFDVIELNYPHEYITGISGEYYKYEANNPHMRSLKFNTNTSEYGPFGTSGSSNDKFAFKLGKSPQFGGFHGTYDASGLQYIGVYLRPKTVLPKIDTGNAEETESKIVLG
What is the function of this protein?
Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance.
What are the official names of this protein?
Protein RESTRICTED TEV MOVEMENT 1, Jacalin-related lectin 1, Restricted tobacco etch virus movement protein 1.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Soluble protein present in sieve elements in a punctate pattern of 1 to 2 um spheres.
Protein: RM11_SCHPO
Sequence: MRCSVAVRASSIYVKNPQLRKSFLHSNYVQLIQESPNFLILQHNNLLPREAKSLRTELKAKVPGSKLQVIRGSIFHHALKVYESIDRLSNGCVDMQKVNLIETHKKAQKIKLDIDNLFVGPLAIFTLGPKLSPEAIRGFMSVLKGYQNKILLLGIRAESKGMDPFEVENLSKIPSLEFLQSSLLSVLSSPASQLRRILDLSKANVAYTLERREPSE
What is the function of this protein?
Involved in mitochondrial genome encoded proteins translation.
What are the official names of this protein?
54S ribosomal protein L11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Mitochondrion.