PharMolix/UniProtQA huggingface dataset:
Protein: G3P_CLOPA
Sequence: MTKVAINGFGRIGRLALRRILEVPGLEVVAINDLTDAKMLAHLFKYDSSQGRFNGEIEVKEGAFVVNGKEVKVFAEADPEKLPWGELGIDVVLECTGFFTKKEKAEAHVRAGAKKVVISAPAGNDLKTIVFNVNNEDLDGTETVISGASCTTNCLAPMAKVLNDKFGIEKGFMTTIHAYTNDQNTLDGPHRKGDFRRARAAAVSIIPNSTGAAKAIAQVIPELKGKLDGNAQRVPVPTGSVTELISVLKKNVTVEEINAAMKEAANESFGYTEDEIVSADVVGISYGSLFDATLTKIVDVDGSQLVKTVSWYDNEMSYTSQLVRTLEYFAKIAK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, CP 17/CP 18, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASLC_HUMAN
Sequence: MSSVFGKPRAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEKSPLTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINLKEMPTVAQAKLVTVKSSRAQSKRKAPTLTLLKGFKIF
What are the official names of this protein?
Ras-like protein family member 12, Ras-like protein Ris.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
Protein: LYS1B_LUCSE
Sequence: MKFINFFVIALMAYANCAWAKTFTRCSLARAMYALGVPKSELARWTCIAKYESHYRTHVVGPANTDGSHDYGIFQINDRYWCKPSNGRSSHNGCNVYCDDLLEDDISESVYCAQHVKSKQGWSAWTTWAKCNGNLPSIDECF
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function (Probable).  Shows antibacterial activity against Gram-positive bacterium M. luteus but shows no activity against Gram-negative bacterium E. coli (PubMed:25098233).  Likely to play a role in the eradication of ingested pathogens during their passage through the intestine (Probable).
What are the official names of this protein?
Lysozyme 1B, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRB_STAA9
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: TCS3_CAMSI
Sequence: MELAMGKVNEVLFMNRGEGESSYAQNSSFTQQVASMARPALENAVKTLFSKDFHLQALNAADLGCAAGPNTFAVISTTKRMMEKKCRELNCQTLELQVYLNDLFGNDFNTLFKGLSSEVVGNKCEEVPCYVMGVPGSFHGRLFPRSSLHLVHSSYSVHWLTQAPKGLTSREGLALNKGKIYISKTSPPVVREAYLSQFHEDFTMFLNARSQEVVPNGCMVLILRGRKASDPSDMESCFTWELLAIAIAELVSQGLIDEDKLDTFNIPCYFPSLEEVKDIVERDGSFTIDHMEGFELDSLQMQENDKWVRGENFTKVVRAFTEPIISNQFGHEIMGKLYDKFTHIVVSDLEAKLPKTTSIILVLSKIDG
What is the function of this protein?
Involved in the biosynthesis of caffeine (PubMed:26773541).  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of theobromine to caffeine (PubMed:26773541).
What are the official names of this protein?
Caffeine synthase 3, TCS1e.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: CTPAL_STAEQ
Sequence: MNDHQKNHATSQDDNTKSTPSKNSKHIKIKLWHFILVILGIILLTSIITVVSTILISHQKSGLNKEQRANLKKIEYVYQTLNKDYYKKQSSDKLTQSAIDGMVKELKDPYSEYMTAEETKQFNEGVSGDFVGIGAEMQKKNEQISVTSPMKDSPAEKAGIQPKDIVTQVNHHSVVGKPLDQVVKMVRGKKGTYVTLTIKRGSQEKDIKIKRDTIHVKSVEYEKKGNVGVLTINKFQSNTSGELKSAIIKAHKQGIRHIILDLRNNPGGLLDEAVKMANIFIDKGNTVVQLEKGKDKEELKTSNQALKQAKDMKVSILVNEGSASASEVFTGAMKDYHKAKVYGSKTFGKGIVQTIREFSDGSLIKYTEMKWLTPDGHYIHGKGIRPDVSISTPKYQSLNVIPDNKTYHQGEKDKNVKTMKIGLKALGYPIDNETNIFDEQLESAIKTFQQDNNLKVNGNFDKKTNDKFTEKLVEKANKKDTVLNDLLNKLK
What are the official names of this protein?
Probable CtpA-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: G6PI_MESFL
Sequence: MIKVDLQHSGLSIADLNEAKVKKVHEMIINKSGKGNDFLGWIEWPKTFDKKEYEEMKKVASSLRNKIDVLVTVGIGGSYLGIRAADEMIRGINHSDKVQVIYAGHTMSSTYVAQLSEYLKGKKFGICVISKSGTTTEPGIAFRALEKQLIEQVGVEASKELIVAVTDSSKGALKTLADNKGYPTFVIPDDIGGRFSVLTPVGIFPLLVAGVNTDNIFAGAIKAMDELVQGDLTNEAYKYAAARNALYNAGYKAEALVAYELQMQYTAEWWKQLFGESEGKDNKGLYPTSMIFSTDLHSLGQWVQEGARNVLFETVIKVKEPVANMLVEADTDNYDGLNYLSGKSFHEINSTAIEGVIDAHVNTGKMPNIVLEFDKMNDVQFGYLVYFFEIAVAMSGYLLEVNPFDQPGVEVYKYNMFKLLGKPGVK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHAB_STRT1
Sequence: MTLNQLLQKLEATSPILQANFGIERESLRVDRQGQLVHTPHPSCLGARSFHPYIQTDFCEFQMELITPVAKSTTEARRFLGAITDVAGRSIATDEVLWPLSMPPRLKAEEIQVAQLENDFERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFQESDQTDMIAFKNALYLKLAQNYLRYRWVITYLFGASPIAEQGFFDQEVPEPMRSFRNSDHGYVNKEEIQVSFVSLEDYVSAIETYIEQGDLIAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQTTMDTVHLLILAFLWLDSPENVDQALAQGHALNEKIALSHPLEPLPSEAKTQDIVTALDQLVQHFGLGDYHQDLVKQVKAAFADPNQTLSAQLLPYIKDKSLAEFALNKALAYHDYDWTAHYALKGYEEMELSTQMLLFDAIQKGIHFEILDEQDQFLKLWHQDHVEYVKNGNMTSKDNYVVPLAMANKTVTKKILADAGFPVPSGDEFTSLEEGLAYYPLIKDKQIVVKPKSTNFGLGISIFQEPASLDNYQKALEIAFAEDTSVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVIGDGKHTIRELVAQKNANPLRGRDHRSPLEIIELGDIEQLMLAQQGYTPDDILPEGKKVNLRRNSNISTGGDSIDVTETMDSSYQELAAAMATSMGAWACGVDLIIPDETQIATKENPHCTCIELNFNPSMYMHTYCAEGPGQAITTKILDKLFPEIVAGQT
What is the function of this protein?
Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
What are the official names of this protein?
Glutathione biosynthesis bifunctional protein GshAB, Gamma-GCS-GS, GCS-GS.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
Protein: WFAP_ECOLX
Sequence: MELVSIIIAAYNCKDTIYATVESALSQTYKNIEIIICDDSSTDDTWDIINKIKDSRIICIKNNYCKGAAGARNCALKIAKGRYIAFLDSDDYWVTTKISNQIHFMETEKVFFSYSNYYIEKDFVITGVFSSPPEINYGAMLKYCNIACSTVILDRTGVKNISFPYIDKEDYALWLNILSKGIKARNTNLVDTYYRVHAGSVSANKFKELIRQSNVLKSIGIKAHHRIICLFYYAINGLIKHCFSYRDKRNA
What is the function of this protein?
Catalyzes the addition of Glc, the second sugar moiety of the O56-antigen repeating unit, to GlcNAc-pyrophosphate-undecaprenol.
What are the official names of this protein?
UDP-Glc:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-glucosyltransferase WfaP.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSTB_NITEU
Sequence: MQIFKPASGHTHSTVQKSVVNKLNFYYGGYQALKNIDMMVYEKQVTALIGPSGCGKSTFLRCFNRMHDLYPRNHYEGEIILHPDNANILSPEVDPIEVRMRISMVFQKPNPFPKSIFENVAYGLRIRGVKRRSILEERVENALRNAALWEEVKDRLGDLAFNLSGGQQQRLCIARALATDPEILLFDEPTSALDPIATASIEELISDLRNKVTILIVTHNMQQAARVSDYTAYMYMGELIEFGATDTIFIKPKNKQTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL4_LEPCP
Sequence: MQLELLNEQGQATAKVDAPDTVFARDYNESLIHQIVVAYQANARQGTRAQKDREQVHHSTKKPFRQKGTGRARAGMTSSPLWRGGGRIFPNSPDENFTQKVNKKMYRAGMASIFSQLAREGRLAVIDSITLDAPKTKLLAAKLKAMNLDHVLVIADEVDENLFLASRNLANVLVVEPRYADPLSLVFYKKILVTKAAIDKLQEMFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KAX1I_RHOJU
Sequence: IVIDVPCTVSKECWSACKKAVGTDRGKCMGKKCKCYP
What is the function of this protein?
Blocks high conductance calcium-activated potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 1.18, Peptide Rj1m1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBC_OENBI
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSILFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPALSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TIG_STAA8
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ARLY_NITMS
Sequence: MYRSRLGNDLSDITLDYVSSIDDDAAITFYDIVGSQAHVLMLYQQKIITKSDAKKILSSLESLKDETFDSSSGAEDIHELIEALVIKRAGMSSGGKMHTARSRNDQVVLDIRMKIRDDINIICNCLLDTIEALVSVAKNHQKTIMPLYTHLQQAQAGLFSHYLLAHADVLSRDFQRLYGTFERINQSPLGAGPVGGTSISIDRRSTAKMLGFDDVVENSIDATSTRDFVAEYVSMVSILMTNLSKIAEDFVIWSTSEFSFIELSDEFTSPSSVMPQKKNPDILELTRGKTSEVIGNLTAILTTVKGLASGYGRDLQQIKSSIWSTSKISISALLIFKSMLLTLKVNEKQMKKVTESSNLIALDIAEKLVQEGIPFRVTHKIAGSLTQLAHLSKKPISKLTPSDIKKSVADTKVDPKLVLEIISSITVVSSLKERKSYGSSGYDEQKRMISDRLKKINDFRTDLTHRENKINSSLEDLKKQIDEII
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHND1_PROM0
Sequence: MFNLKYFLVSSSLLFSVFSSPVFSNPKVLKVGAIPDQNQDVLDKRFNLFSKELSKQLDVEVKYIPVINYIAAVTGFRTKDLDLVWFGGLSGVQARLQTPNSIVIAQRDIDKEFKSVFVVNKNLELNSISNIKGLKKLKNLRFTFGSENSTSGRLMPEYFLNQAGVEIKHFKGKKAGFSGSHDATIALVNSGAFDAGALNKQVWENNLKNNPKRTSNLELFWITPEYVDYHWVAQGDLENRFGEGFTKELKSVILNLDIKQKSHKQILDMFNAKRFIKAESKQYKNIEEIGRKLNKIR
What is the function of this protein?
Probably part of the ABC transporter complex PhnD1C1E1.  Binds strongly to inorganic phosphite and with very weak affinities to methylphosphonate (MPn) and phosphate.
What are the official names of this protein?
Probable ABC transporter phosphite binding protein PhnD1.
What is the protein family that this protein belongs to?
Belongs to the phosphate/phosphite/phosphonate binding protein family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYA_MYCGA
Sequence: MNKHLSGSQIRQIWLDFFKSKKHEIIESKSLVPINDPSLLWINAGVATLKKYFSGEENPINPRLANSQRCIRANDIENVGVTSRHHTVFEMLGNFSIGDYFKKEAIEFGYELLTKFYGLNKDKLYITIYEDDNDAFNYWVGQGINPHHIIRCDRKRNFWDLGSGPCGPSTEIYYDRGEKYDPNKLGEKLFFEDIENDRYIEVWNIVFSQFNNTGNNNYTELLRKNIDTGASLERFACILQDVPTNYDTDLYLPIIRTIEKHTNHKYVVDHYFSKDQSEQDVLRAFRVIADHLKCGVFAIADGVLPGAKDRDYIIRKLLRRAFVYAKKLNAKPEYLVETINVIINTYSDFFKYLIPNKEIVIQAITNEANNFTKTLDYGFEIFNEAKTTNNITAETIFKLVETYGFPLDLIKELSAEAKIKLDLDGFEELFKKHQEISKANNGEVGLKKQNENLLKFKTPSKFFYDKNNIKTKVVAIFDDKFNPVDQIEVGSGWAVFESTPIYATSGGQRFDEGYCLKKGNLVVHFDNVIKAPNKQHLHHFKKASFWLNEKVELMHDENWRKLVRKNHSLEHILHATLKNTISETIKQSGAFKSAAKATLDFNYPTRLTDEDLDKIETKMRQVIADKIPVTVHHVDYETSQKMNAIAYFEEEYKKHELLRVIKIGDYSVELCGGTHVDNTKEIEECFITNLYSLGAGRWRIEIMSSYETIYNYLVDKQNEIKQEKDHMFNELGNYDLTHYLDFSKKLHSFNLPNSIKDLRKTLRAFEQIKEEYKAIKLELDKKKTKDRANQIKKLALDNLEHKIVLLFFDKEEHKALSIAHSELVNEKPDHLFFFINKSDNKINYLIGIKNATYKLNAKLLIDKVNAMFGAKGGGKQNFAQGGFSTDKDVGKLKADFVNICIT
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIG12_HUMAN
Sequence: MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK
What is the function of this protein?
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.  The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
What are the official names of this protein?
Sialic acid-binding Ig-like lectin 12, Siglec-12, Sialic acid-binding Ig-like lectin-like 1, Siglec-L1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: T179A_HUMAN
Sequence: MALNNFLFAQCACYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFSAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQDIDLELGVDNSAFYDQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLIHEKELLLARPSPRTSFQEEKSAVI
What are the official names of this protein?
Transmembrane protein 179, Transmembrane protein 179A.
What is the protein family that this protein belongs to?
Belongs to the TMEM179 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHO2_PYRTR
Sequence: MADVGDLKADGSQLRERPSAKPLHLNNSDDAKQKVLKLNDQEDKDHKNDESKKRTYGRTPDGTVFIVPQTHDMVSQLLSPSQPKNLSDIAVLAVLASLILTFYALPKSARVPIFAIIFLFWRAGYNAGIGWLLDGQSKHNRLVLWAKQSHIFEKPETGKNPNPALYKLLKRELETKIPKDYKFEEAPLEYNTWLVFRRVVDLILMCDFVSYCLFALACFNRPQESWFLWALRWTTGIILFLFNLWVKLDAHRVVKDFAWYWGDFFYLIDQSLTFDGVFEMAPHPMYSVGYAGYYGIALMMASYKVLAISIIAHAAQFAFLILVESRHIDKLYNPPPPRLKTFLFVNAFAWRLWYTLGLGYILDRQSKKKNWTKHFIKYGDTKEEAWRQWKSLYHLSMTMSHASFVALAWKMYSLPPDGLTGLTLFRHVLGAGMIALQVWTAMSIYESLGEFGWFCGDFFFDPPSKSLTYNGIYRFLNNPERVLGLAGVWGIAIITWSPAVFYVATTAHILNLAFLQFVEKPHVIKLYGENLREMSGVSKTVRQALPDPVRQWQSAADQYINTTVESIEAMLDRARSKFAGSVDTFVNDTTSLFKSYPARIPISRHHSEDLSGLNLKQYKLEIEGTTLPPAVEQQKNGGREGELARTPAIRTNDFKTLCLEYGAPIRVRWQAPLNHSKKDWIGLYMVTDNQSRKVTRISSNGRWVATNPDAFDSTRADDGILVSDKLLPANDNDEESTDCYTGEVEFHGDKLWWTTGVFEFRYHHGGRHHVMALSQAFEIRIPKFDETDVEVDDNGTIHRAVEETLLPIIQNCFDRDPEIAPSTSEEPFGSLVERDGKFARRVVFAVHQMFGIEFAPEVVQADGTVRNLAWRICNAKKVLAPYSMSATHGRNTPTMG
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UGDH3_ARATH
Sequence: MVKICCIGAGYVGGPTMAVIALKCPSVEVAVVDISVPRINAWNSDQLPIYEPGLDDVVKQCRGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVSDKIVVEKSTVPVKTAEAIEKILTHNSKGIKFQILSNPEFLAEGTAIEDLFMPDRVLIGGRETTEGFAAVKALKDIYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSALCEATGANVSEVSYAVGKDSRIGPKFLNSSVGFGGSCFQKDILNLVYICECNGLPEVAEYWKQVIKINDYQKTRFVNRIVSSMFNTVSNKKIAVLGFAFKKDTGDTRETPAIDVCKGLLGDKARLSIYDPQVTEEQIQRDLTMNKFDWDHPLHLQPMSPTTVKQVSVAWDAYTATKDAHGICILTEWDEFKKLDFQRIFENMQKPAFVFDGRNVVDADKLREIGFIVYSIGKPLDQWLKDMPALA
What is the function of this protein?
Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.  Required for the formation of cell wall ingrowths on the outer cell walls of nematode-induced syncytia.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase 3, UDP-Glc dehydrogenase 3, UDP-GlcDH 3, UDPGDH 3, At-UGD3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: CH60_ALKEH
Sequence: MAAKEIRFSDDARQRMMKGVNTLANAVKATLGPRGRNAVLDKSFGAPTVTKDGVSVAKEIELEDKFENMGAQMLKEVSSQTSDIAGDGTTTATVLAQAILREGMKAVAAGMNPMDLKRGIDKGVSAATKYLADELSKPCETDTSIAQVGSISANSDESVGRIIADAMQKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQQSMKAELEDAFILLHDKKISNIRDLLPLLENVAKANKPLLIISEDIEGEALATLVVNSIRGIVKVAAVKAPGFGDRRKAMLQDIAVLTGGTVISEEVGLSLEKATLDDLGQAKKVDVSKEETTIVGGAGRHDDIMARVEQIRAQIEESTSEYDKEKLQERVAKLAGGVAVIKVGATSEIEMKEKKARVEDALHATRAAVEEGIVPGGGTALLRAQASLDGLEYANHDQEVGINIVRRAMEEPLRQIVYNAGGDGAVVVNEVRNGEGNYGYNAQSGEYGDLVEMGILDPTKVTRTALQNAASVAALMITTEVMVADLPKDDDAGAGGGMGDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_NITHX
Sequence: MSRRHSAEKREVLPDPKFGNVVITKFMNSVMYAGKKSVAEGIVYGALDLIEAKTRQGPLTVFEQALENVMPTIEVRSRRVGGATYQVPVEVRSTRRQALGIRWLIAAARGRNEKTMTERLSAELLDASNNRGSAVKKREDVHKMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YIDD_ENT38
Sequence: MAPPLSPGSRVLIGLIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FL2D_DROME
Sequence: MSVAAMTMDDQRPCMNSYDKMPPTKYEQNLNILNSSQNSGATGGPASPTPSGLEDHHHHHHPHPHHHHHQEQQQQQQQQQHLQQQQQQQQQQHAAAVAEAVAAAEQRQRLLEDEIENLKLEQVRMAQQCADAQRREKILMRRLANKEQEFQDYVSQIAEYKAQQAPTALALRTALLDPAVNLLFERLKKELKATKAKLEETQNELSAWKFTPDSNTGKRLMAKCRLLYQENEELGKMTSNGRLAKLETELAMQKSFSEEVKKSQSELDDFLQELDEDVEGMQSTILFLQQELKTTRDRIQTLEKENAQLKQAIKDEVVAPAAATNGGTNTTINKLETIHEDACMANNPTNPDCYNGNTNNEQIAAVPQIPLSDDGSNMNGNAARLARKRNYQEEEALPTVVVVPTPTPVGNNVQEAPPIREVTAPRTLPPKKSKLRGITTRRNSQLEEDHQPVTTPVAVPMIVDNAVAGMASEEAAAAAAAVNNSNTGIIPETGVQVGVPVEGGDPGAPAAPGRILTRRRSVRMQQNGSGAVDYST
What is the function of this protein?
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination (PubMed:27919077).  Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy (PubMed:1695150, PubMed:27919077).  M6A methylation is also required for neuronal functions (PubMed:27919077).  Required for proper inclusion of regulated exons in Ubx transcripts, leading to isoforms Ia/b and IIa/b (PubMed:10101174).
What are the official names of this protein?
Pre-mRNA-splicing regulator female-lethal(2)D, dFL(2)D.
What is the protein family that this protein belongs to?
Belongs to the fl(2)d family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRP_BRUSU
Sequence: MSSFKPSRFSTARLTGDAVTPKSIYLRRREFMIGLGAIAATGAASSAFADPLEAKTTAYKVDEKLTPQNAVTTYNNFYEFGTDKSDPSANSGSFKPLPWKLTVDGLVKQPKEFDVEELIAKMPLEERIYRMRCVEAWSMVIPWIGFPLSSLLSQVEPLGSAKYIAFTGVVRPDEMPGQTGLFQALNWPYVEGLRLDEAMHPLTILSVGLYGETLPNANGAPIRLVVPWKYGFKGIKAITRISFVEKQPPTSWNRQAANEYGFYANVNPAVDHPRWSQATERRIGEGGFFGSDRRPTLPFNGYGEEVASLYAGMDLKANY
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.