PharMolix/UniProtQA huggingface dataset:
Protein: SYS_SHIDS
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSCWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_ECOL5
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_CAUSK
Sequence: MAMAETPVPKKGDKTKVAAERRGGWLSRIAPGVRGAFAKRETPENLWVKCPDTGEMIYRSDLEAALWVTPAGRHMRIGPELRFKFTFDDGEHEVLPTPAVFEDPLRFSDGKPYKERLAAARKATGEQDAMAIGYGKVGGAPAVVLVQDFAFMGGSLGMAAGEGFIAAAEAAIARQVPLVAFTAAGGARMQEGALSLMQMARTTLAINMLKDAGLPYVVVLTDPTTGGVTASYAMLGDVHLAEPGALIGFAGPRVIEQTIRETLPPGFQRSEYLVEKGMVDRVTPRKELPAVLGSILGTLMMGRGLKAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_CAMJE
Sequence: MEVKAKQLDSVNATASVKIPSGMIKSEVENLAKKASKSVKMDGFRPGKVPVSAVLKRYERELTQDAEQNLFKSAVNSALQELKKENKELVGEPYFEKFDRKDGEIIAELILSFKPEIKLEGYEKLIPEYQTPKVSKKEIDEKKDELLKRFATPEAIKTKRALKEGDFAKFDFEGFVDDKAFEGGKAENYVLEIGSKQFIPGFEDGMVGMKIGEEKDIKVTFPKEYGAAHLAGKDAVFKVKLHEIQELKIPELDDEMLKKLLPGEEKASVEVLDEKLKEQIKNEKLFKLVNDELKGKFADALIEKYNFDLPKGIVEQETDMQMRAAFNTFSEKEIEELKASKEKYQEKRDSFKEEAQKSVKLTFIIDELAKLRKIEVNDQELIQAIYFEAYRYGMNPKEHLENYKKQGALPAVKMALIEEKLFNDIFIPKTEKSEKVSKKEKEDK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Y378_MYCLE
Sequence: MSIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHAALFGLPLCEPIYPTPAGLVAAVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWPAAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRRLLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ
What are the official names of this protein?
Uncharacterized protein ML0378.
Protein: TRHO_VIBPA
Sequence: MSQYVVCALYKFVELNNYQELREPLLALMEKHHIRGTLLLAGEGINGTVASDRAGIDTLLEWLNTEPRLTGTVYKESYSETQPFNRTKVKLKKEIVTLGVEGIDPRHVVGTYVKPQDWNDLIADPEVFVVDTRNDYEIEIGTFKGAVNPNTETFREFPDYVKENMDPAKHKKVAMFCTGGIRCEKSTAYMKEQGFEEVYHLEGGILKYLEEVPQEESMWEGDCYVFDGRVAVNHQLEKADYDLCNACRLPITDEDKQSELFEQGVSCPKCHGKHSEEQVERFREREKQVSLANQRGEQHVGGESAKQRAQRREAKLAKKAAQRKQA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: TM243_BOVIN
Sequence: MEDFSTRTYGTSGLDNRPLFGETSAKDRIINLVVGSLTSLLILVTLISAFVFPQLPPKPLNIFFAVCISLSSITACILIYWYRQGDLEPKFRNLIYYILFSIIMLCICANLYFHDVGK
What are the official names of this protein?
Transmembrane protein 243.
What is the protein family that this protein belongs to?
Belongs to the TMEM243 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPF2_VIBC1
Sequence: MNLNASMFGQAISFVIFVWLCMKYVWPPLVKLLDERRAEIAQGLEQTEKAAQELELAKANGEALLTEARSKAQAIINQGKQRQEQMVAEAVDLANQEKARIVAEGKAEVESERSKVRQELKDEMADLVIESASKLINRNLDSSANRDLVNRFINEM
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NR4A1_BOVIN
Sequence: MPCIQAQYGTPAPSPGPRDHLAGDLLTPELSKPTMDLASPEAAPAVPTALPSFSTFMDGYTGEFDTFLYQLSGTAQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGTLSGPLDETLSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGPFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPPGPSPSLAPSPLKLFPSQAAHQLGEGESYSMQTAFPGLVPTSPHLDGSGRLDAPVTSAKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPETSPAHLLTSLVRAHLDSGPSTSKLDYSKFQELALPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPGDQDLLLESAFLELFILRLAYRSKPAEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLVVDIPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVSAEAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIVDKIFMDTLPF
What is the function of this protein?
Orphan nuclear receptor.  May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.  Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'.  May inhibit NF-kappa-B transactivation of IL2.  Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity).  Plays a role in the vascular response to injury (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 4 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Note=Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27. Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (By similarity).
Protein: KCP3_PINMA
Sequence: MIRLVTLAALPVLVLCQFDPSKWFMGSNLGGLQGFGVLPARCLNYLEAGYSRGNRLPSHRFFFNSTSGNCEQFVYYGRGGNRNNFRDVFKCMKSCGCKQQRNGGVPCNPPSQPVVRYYYDTFTKLCNTFQHTGCGGNSNHFKDWNDCFFTCGNGFET
What are the official names of this protein?
BPTI/Kunitz domain-containing protein 3, Nacre serine protease inhibitor 2, NSPI2.
What are the subcellular locations of this protein?
Secreted.
Protein: TDXH_AQUAE
Sequence: MEVVSLPRLGEPAPAFEAQTTFGPVKFPDDFKGQWVVLFSHPADFTPVCTTEFVAFAKNYEEFKKRNVQLIGLSVDSNFSHIAWVMNIKEKFGIEIPFPIIADHNMEVAKKYGMIHPAQSTTFTVRALFVIDDKGILRAMIYYPLTTGRNIREVIRLVDALQTADREGVATPADWVPEPQTWEFTEENTKVIVPPPTTYEDAVKRLQEGYECADWYICKKKV
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_UREU1
Sequence: MTKEIILGIDLGTTNSCVAVIENKKPIVLENPEGKRTVPSVVSFNGDEVLVGDAAKRKQITNPNTVSSIKRLMGTKEKVTILNKEYTPEEISAKILSYIKDYAEKKLGTKINKAVITVPAYFDDAQRQATKNAGIIAGLTVERIINEPTAAALAYGIDKLDKEQKILVFDLGGGTFDVSVLDMADGTFEVLSTSGDNHLGGDDWDQVIINWLLKSIADEFNIDLSKNKMAMQRLKDAAEKAKIELSGVNTTTISLPFIAMDSSGQPINFEKELNRATFDNLTKNLIERLKKPVLDAMKESKLSLADIDQVLMVGGSTRMPAVQNLVKELTGKEPNHSLNPDEVVAIGAAIQGGVLAGEIDDILLLDVTPLTLSIETMGGVATPLIPRNTKIPVSKSQVFSTAADNQPSVDIRIVQGERSLAADNKLLGNFELSGIEPAPRGVPQIEIKFNIDANGIMSVNAKDLKTQKETSITIKDSQGLSQEEIDKMIKEAEENKEKDAKVKHERELVNRADSLINQLEQVVKTENVPQEQKDAFNKQIEELTNARDAQDYTKLEAEVKKVEDLLANAAKFAQQTQQQDPNNQKDDVTEATVTDDSTKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS3_SALPC
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RS17_PSEU2
Sequence: MAEAEKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDETNQCHIGDKVTIRETRPVAKTKSWALVDILERAVEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PMA9_ARATH
Sequence: MAGNKDSSWDDIKNEGIDLEKIPIEEVLTQLRCTREGLTSDEGQTRLEIFGPNKLEEKKENKVLKFLGFMWNPLSWVMELAAIMAIALANGGGRPPDWQDFVGITVLLIINSTISFIEENNAGNAAAALMAGLAPKTKVLRDGKWSEQEAAILVPGDIISIKLGDIVPADGRLLDGDPLKIDQSALTGESLPVTKHPGQEVYSGSTCKQGELEAVVIATGVHTFFGKAAHLVDSTNQEGHFQKVLTAIGNFCICSIAIGMLIEIVVMYPIQKRAYRDGIDNLLVLLIGGIPIAMPTVLSVTMAIGSHRLSQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLTVDKSMVEVFVKDLDKDQLLVNAARASRVENQDAIDACIVGMLGDPREAREGITEVHFFPFNPVDKRTAITYIDANGNWHRVSKGAPEQIIELCNLREDASKRAHDIIDKFADRGLRSLAVGRQTVSEKDKNSPGEPWQFLGLLPLFDPPRHDSAETIRRALDLGVNVKMITGDQLAIGKETGRRLGMGTNMYPSSALLGQDKDESIASLPVDELIEKADGFAGVFPEHKYEIVKRLQEMKHICGMTGDGVNDAPALKRADIGIAVADATDAARSASDIVLTEPGLSVIVSAVLTSRAIFQRMKNYTIYAVSITIRIVMGFMLLALIWKFDFSPFMVLIVAILNDGTIMTISKDRVKPSPLPDSWKLKEIFATGVVLGTYLAVMTVVFFWAAESTDFFSAKFGVRSISGNPHELTAAVYLQVSIVSQALIFVTRSRSWSYVERPGFWLISAFFMAQLIATLIAVYANWNFARIRGIGWGWAGVIWLYSIVFYIPLDILKFIIRYSLSGRAWDNVIENKTAFTSKKDYGKGEREAQWAQAQRTLHGLQPAQTSDMFNDKSTYRELSEIADQAKRRAEVARLRERHTLKGHVESVVKQKGLDIEAIQQHYTL
What is the function of this protein?
The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
ATPase 9, plasma membrane-type, Proton pump 9.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DXS_PSEPF
Sequence: MPTTFHEIPRKRPTTPLLDRANTPDGLRRLGEAELETLADELRLELLYTVGQTGGHFGAGLGVIELTIALHYVFDTPDDRLVWDVGHQAYPHKILTGRRERMETLRQKDGIAAFPRRSESEYDTFGVGHSSTSISAALGMAIAARLQNSDRKAIAVIGDGALTAGMAFEALNHAPEVDANMLVILNDNDMSISRNVGGLSNYLAKILSSRTYASMREGSKKVLSRLPGAWEIARRTEEYAKGMLVPGTLFEELGWNYIGPIDGHDLPTLIATLRNMRDLKGPQFLHIVTKKGKGFAPAEVDPIGYHAITKLEPLDAPAAAPKKAGGPKYSGVFGEWLCDMAAADPRLVGITPAMKEGSDLVAFSERFPLRYFDVAIAEQHAVTLAAGMACEGAKPVVAIYSTFLQRGYDQLVHDVAVQNLDVLFAIDRAGLVGEDGPTHAGSFDLSFLRCIPGMVIMTPSDENELRKMLTTGHLYNGPAAVRYPRGTGPNATIEKDLEPIEIGKGVVRRQGSKVALLVFGVQMAEALKVAETLDATVVDMRFVKPMDEALVREIANSHDLLVTIEENAIMGGAGGAVSEFLARENILKSVLHLGLPDVYVEHAKPAQMLAECGLDEVGIEAAVRERLELLNR
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RDRP_BPPH6
Sequence: MPRRAPAFPLSDIKAQMLFANNIKAQQASKRSFKEGAIETYEGLLSVDPRFLSFKNELSRYLTDHFPANVDEYGRVYGNGVRTNFFGMRHMNGFPMIPATWPLASNLKKRADADLADGPVSERDNLLFRAAVRLMFSDLEPVPLKIRKGSSTCIPYFSNDMGTKIEIAERALEKAEEAGNLMLQGKFDDAYQLHQMGGAYYVVYRAQSTDAITLDPKTGKFVSKDRMVADFEYAVTGGEQGSLFAASKDASRLKEQYGIDVPDGFFCERRRTAMGGPFALNAPIMAVAQPVRNKIYSKYAYTFHHTTRLNKEEKVKEWSLCVATDVSDHDTFWPGWLRDLICDELLNMGYAPWWVKLFETSLKLPVYVGAPAPEQGHTLLGDPSNPDLEVGLSSGQGATDLMGTLLMSITYLVMQLDHTAPHLNSRIKDMPSACRFLDSYWQGHEEIRQISKSDDAILGWTKGRALVGGHRLFEMLKEGKVNPSPYMKISYEHGGAFLGDILLYDSRREPGSAIFVGNINSMLNNQFSPEYGVQSGVRDRSKRKRPFPGLAWASMKDTYGACPIYSDVLEAIERCWWNAFGESYRAYREDMLKRDTLELSRYVASMARQAGLAELTPIDLEVLADPNKLQYKWTEADVSANIHEVLMHGVSVEKTERFLRSVMPR
What is the function of this protein?
Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them.
What are the official names of this protein?
RNA-directed RNA polymerase, Protein P2.
What are the subcellular locations of this protein?
Virion. Note=Found in the capsid (12 copies). Prior to RNA packaging, localizes on the inner procapsid surface near the three-fold axis of symmetry.
Protein: SECG_AERPE
Sequence: MSVRRRRERRATPVTAAGLLSFYEEYEGKIKISPTIVVGAAILVSAVVAAAHIFLPAVP
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex (By similarity).
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AAEB_ECO7I
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFNQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLTGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTF1_HUMAN
Sequence: MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
What is the function of this protein?
Zinc-dependent transcriptional regulator of cellular adaption to conditions of exposure to heavy metals (PubMed:8065932).  Binds to metal responsive elements (MRE) in promoters and activates the transcription of metallothionein genes like metallothionein-2/MT2A (PubMed:8065932).  Also regulates the expression of metalloproteases in response to intracellular zinc and functions as a catabolic regulator of cartilages (By similarity).
What are the official names of this protein?
Metal regulatory transcription factor 1, MRE-binding transcription factor, Transcription factor MTF-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Translocation to the nucleus is induced by metals.
Protein: PRRC1_HUMAN
Sequence: MMEESGIETTPPGTPPPNPAGLAATAMSSTPVPLAATSSFSSPNVSSMESFPPLAYSTPQPPLPPVRPSAPLPFVPPPAVPSVPPLVTSMPPPVSPSTAAAFGNPPVSHFPPSTSAPNTLLPAPPSGPPISGFSVGSTYDITRGHAGRAPQTPLMPSFSAPSGTGLLPTPITQQASLTSLAQGTGTTSAITFPEEQEDPRITRGQDEASAGGIWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIHLETFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVSRTDWHMAFTGMSRRQMIYSAARAIAGMYKQRLPPRTV
What are the official names of this protein?
Protein PRRC1, Proline-rich and coiled-coil-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: YEAH_ECOUT
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: SP5G_STAAS
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: COXC_THUOB
Sequence: SHGKQETDEEFDARWVTYFNKSDI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A-2, mitochondrial, Cytochrome c oxidase polypeptide Va-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: AROE_EDWI9
Sequence: MQQFAVFGHPIKHSQSPRIHRLFAQQTGIALSYEAMLAPLDDFPAFAMAFFQQGGRGANVTTPFKEQAWQMADVLTPRARLAGAVNTLHWQNARLLGDNTDGVGLVSDLHRLAMIGDASRVLLLGAGGAARGVILPLLEQGCRIALANRTHARAQALAAAFQAQGAIEALPYDALGTHTFDLIINATASGLQGELPPLPRSIIRPDCACYDMFYRAGATPFLAWVQQQGAVRLADGFGMLVAQAAHAFSLWHGIMPQIAPVLIQLRQEPVG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ERH_HUMAN
Sequence: MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK
What is the function of this protein?
May have a role in the cell cycle.
What are the official names of this protein?
Enhancer of rudimentary homolog.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THII_STAAS
Sequence: MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAMSAAAIKFAQQFEENSTFKIDVKRADKNFPMDTYELQRELGGAILKHFDNISVNVKRPDHEIRVEVRLDAIYMYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLVHQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ARCFU
Sequence: MFAVVRMRGTVDVHRKIKETLKMLRLHKRYHCVVIPDTPSYRGMLQVVKDYVAYGEINAETLALLLRLRGRLTGNRKLTDEYVKEKTGYETIEEFAKAVVEGKASLKDLPDLKPVFRLHPPRKGIKNIKWHYPRGNLGYHGEEINRLLYKMR
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.