PharMolix/UniProtQA huggingface dataset:
Protein: THII_CITK8
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRARDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDRLEGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAIKAKIEAEEEHFDFSILDKVVEEASNVDIREIAQQTGQDVVEVETVSGFGPNDVILDIRSVDEQDDKPLKIEGVDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFQNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLCT_STAAW
Sequence: MGEYIVTKTLNNNVVVCTNNDQEVILIGKGIGFNKKEGMALNDQTITIEKIYKLESEQQKAHYKSLVEIADDNVLQVIIDSLNFISNTAMNVDSKQLVVSLTDHIIFAYKRLKQNQVISNPFVMETMQLYSDAYHIAKQVIDQLNAALDVHFPEDEIGFIALHIASNTEDLSMHEMTLINNVIKKGIDIIESDLVTTVDKESLQYQRFIRHVQFLIRRLRRKEYIHAQDDFVSMIKNHYPICYNTAYKILTMIQKQFDVNISESEIIYLTLHIHHFEERINQS
What are the official names of this protein?
Protein GlcT.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.
Protein: RSMH_LEGPA
Sequence: MAKHQSVLLHESIKGLAIKADGIYFDGTFGRGGHSREILNHLSDKGRLFAIDKDLDAVQYAKDYFGLDKRFQIFHGSFAQIKEFASQAGVIGAVDGILLDLGVSSPQLDNPERGFSFMLQGPLDMRMDLTQSINAANFVNEAEVNELAHVFRAYGEERFAGRIAKAIVDARKLKPITTTLELAEIVKEANPKWEKHKHPATRVFQAIRIHVNQELTDLSNCLEQCLDVLGPGGRLAVISFHSLEDRIVKQFMRDKEQGNRPPVEVPIKYEELKTNFKKVGKAVKPQSSEIKENVRSRSAVLRIGEKLA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_BUCAP
Sequence: MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSVSISSDINIEKNDFDVLIDFTKPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKKIALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHHRNKIDIPSGTALSIGENISKVMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFNRESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SHEWM
Sequence: MKIQLVAVGTRMPDWVTTGFKEYQRRFPRDMALELVEIPAGKRGKNADIARILHKEGEQMLAAIPKGNHIVSLDLPGKTWTTPQLATQLSRWQLDGRDVSLLIGGPEGLAPSCKQAASQSWCLSALTLPHPLVRVVVAESLYRAWSVNTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HHOB_SYNY3
Sequence: MAIHLKASHLGVAVLLLLFGGAIGAAGGGYLLSSGQNHSSPDSPVNTSPQSLTPAPVESNYRSALPLTLPRSAQDDQELNFIARAVQKIGPAVVRIDSERTAVSQGGPMGDQPFFRRFFGEEMPPNPDPREQGTGSGFILSSDGEVLTNAHVVEGASTVKVTLKDGSVLEGKVMGIDTMTDVAVVKVEAENLPVVEIGQSDRLQPGEWAIAIGNPLGLDNTVTVGIISALGRSSSEVGVPDKRVRFIQTDAAINPGNSGGPLLNAKGEVIGVNTAIRADAQGLGFAIPIQTAQNVAENLFTKGKMEHPYLGIHMVTLTPEMTKQLRTSGELPAGVTADTGVLIIQVSPGSPAAQAGLAPGDIILEVGGMGVKTATDVQERVEVSQIGEPLAIAVKRGQKPQMMAVRPGPFPEDLGQ
What is the function of this protein?
A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA.
What are the official names of this protein?
Putative serine protease HhoB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
Protein: TOLB_SPHAL
Sequence: MSLRPISLMLALLLTSAPALAQSAPTPPATVQTEPRETIEGTLSQERTVIGIPSFATASVQTVAGLRTDALGRQLADVIAADLERSGLFEPIGPNGVRAIGRAEVQAPRFGEWQARGAENVVHGFVDAGSNGSLIVGCYLYDTALGSELVRKGFEIQPADWRRAAHKCADAIYSRLSGEAPFFDSRVAYIAESGPKGNRIKRLAIMDSDGGNHRFITNGQALALSPRFSPDYKKIVYVSYLNDRVRVFIYDVASGTQRLVTESRNPTFAPRWSPDGTQILYSMAVGGNTDIYRISANGGTPVRLTTAPGIDVGGSFSPDGRKIVFESDRSGSQQLYVMNIDGSNQQRISFGGGRYATPEWSPRGDLIAFTRMGGGEFRIGVMTPSGGGVRMLTNGWQDEAPTWSPNGRVIQFFRTTPGREGRSSLWQVDLTGVNLRRLPTPQDGSDPSWGPVLP
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HPCA_PIG
Sequence: MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels.  May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases.
What are the official names of this protein?
Neuron-specific calcium-binding protein hippocalcin.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Association with membranes is calcium-dependent (By similarity). Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (By similarity).
Protein: DNAJ_EXISA
Sequence: MAKRDYYEVLGLDKSASAQDIKRAYRKLARQYHPDINQEADAADKFKEIGEAYEVLSDEQKRAQYDRFGFEGANQFGGGGDFQGGFGDIFDMFFGGGGRRQDPNAPRRGEDYQYVVDLDFMESVTGKTETIELEIEVECDTCMGSGAKPGTKPETCNRCGGSGVETVEQNTILGRMVNQRPCSQCHGSGKTIKEKCPTCHGSGHVKKKQTVEVKIPAGIDNGQQIRLSGKGGPGVNGGPAGDLYVVVRVRAHEIFERVDQHIAMDMPITFAQAALGAEIEVPTVHGNVSLKVPAGTQTGSKFRLRGKGMPSVRGGANGDQYVSVIVMTPKNMTDRQKELLREFEEISGESGVEEEHGMFQKMKKFFSH
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECP1_ASCSU
Sequence: MFLIYLFVQTAESSWLSKTAKKLENSAKKRISEGIAIAIQGGPRRRRFVAEQDAIHSRVSREVPTLSDSV
What is the function of this protein?
Has antibacterial activity against several Gram-positive and Gram-negative bacteria.  Is weakly active against yeasts.  Acts by a nonpore mechanism.
What are the official names of this protein?
Cecropin-P1.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TIG_BIFAA
Sequence: MKISVRNLEPTKVKLTVTVDPEEFNPYLDEARKEIAKQVNVPGFRKGHVPGKIIDQRIGFGAVAGEAVNNGVPELYSKALETKKIHPMAQPEIDVQDVPESAKDETKLKFVATVERRPDIELPALDGMEIEVAKAEVTDEDINNRLEALRQRFGTLVSVDRPAAKGDYANIDLNAEINGETVDSQEGVSYELGSATMLDGLDEALEGLSAGEETSFEGTLEAGKHEGEKALIKVKVNSVKAEELPELDDDFASEASEFDTLDELKEDLKKVAAQDAESRQATAARDAFIAKLEDGLEIPVPKGVKAEMVEQQLKNVTADPSKATKEQKAEAEETVEKELRDQMVLDVLAETMDVKVSQGEVFNFLASIAQQYGMDPNAFIQAIIRNGQIGSAVQEVGRSKGLLSGMRAVTFKSEGETLDLSAFLGEAAEDEESESVEAASAAAAVADSLAADKDAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Z280B_HUMAN
Sequence: MEQSCEEEKEPEPQKNIQETKQVDDEDAELIFVGVEHVNEDAELIFVGVTSNSKPVVSNILNRVTPGSWSRRKKYDHLRKDTARKLQPKSHETVTSEAVTVLPASQLESRSTDSPIIIEPLSKPDYRNSSPQVVPNNSSELPSPLITFTDSLHHPVSTALSVGGINESPRVSKQLSTFEVNSINPKRAKLRDGIIEGNSSASFPSDTFHTMNTQQSTPSNNVHTSLSHVQNGAPFPAAFPKDNIHFKPINTNLDRENELAKTDILSLTSQNKTFDPKKENPIVLLSDFYYGQHKGEGQPEQKTHTTFKCLSCVKVLKNVKFMNHVKHHLEFEKQRNDSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQEPSTVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSSVFADVETHFRTCHENTKNLLCPFCLKIFKTATPYMCHYRGHWGKSAHQCSKCRLQFLTFKEKMEHKTQCHQMFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDVASITVSTSDSEPSLPRSKSKISKKSH
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Zinc finger protein 280B, 5'OY11.1, Suppressor of hairy wing homolog 2, Zinc finger protein 279, Zinc finger protein 632.
What are the subcellular locations of this protein?
Nucleus.
Protein: EXOS5_ORYSJ
Sequence: MEESRADGRNPNQLRPFSCTRNPLDRAHGSARWAQGDTIVLAAVYGPKPGTRKGENPEKASIEVVWKPMTGQIGKQEKEYEMTLKRTLQSICLLTVHPNTTTSVILQVVGNDGSLLPCAINACCAALVFAGIPLKHLAVAIGCGVLEDGEVILDTNKAEEQQLKSFAHLVFPNSRKSASSKEPNQKEEDSERGLITSITHGVMSEEDYFSCIERGLAASSRISDFMRTTLQKQAPGDV
What is the function of this protein?
Probable component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions.  May form a homodimer separately from exosome complexes and function in DNA cleavage process.  Binds double-stranded DNA (dsDNA) and single-stranded RNA (ssRNA), and possesses hydrolytic DNase and phosphorolytic RNase activities in vitro.
What are the official names of this protein?
Exosome complex exonuclease RRP46 homolog, Exosome component 5, Ribosomal RNA-processing protein 46, oRrp46.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TF27_SCHPO
Sequence: MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPEIGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGSLTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILWMLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQPQNKNLGKESLSKKNNTTNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITEETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAISFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKGLEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKKEGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDEHKLAFRCPRGVFEYLVMPYGISIAPAHFQYFINTILGEVKESHVVCYMDNILIHSKSESEHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQPKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLVSPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSDKEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFNFEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTNDTKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGIELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSMDFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEIIADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTWVDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQTVKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVLQKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKNREQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI
What are the official names of this protein?
Transposon Tf2-7 polyprotein, Retrotransposable element Tf2 155 kDa protein.
Protein: XPT_STRP4
Sequence: MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDRFENGQVVFKEADL
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPB_SALTI
Sequence: MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAENMEVSGATFTNGLLYIDLTRNEPETIPPQRIAINERSALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_DEHMB
Sequence: MKLIIGLGNPGKEYSGNRHNVGFQCLSRFAKENHISFDKKCCLSRTGSGRINDEEIVLAKPQTYMNLSGKAVNQLLRRYNLKAADIIVVQDDLDLPAGKLRLRLGGSAGGHNGVSSIITDIGTKEFIRLKIGIGKPDARNNGAEVVDHVLGNFGGEEREIIETAIARAAEALACLITSGLDTASNRFNC
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_FRATO
Sequence: MSKLTIVRGFNDVLPLDSYKWQFLESKVKLILDRYNYSETRLPIVERSELFHRSVGESSDIVSKETYDFQDRNGDSLTLRPEGTAGCVRMVIENNLATRGQTQKLWYCGPMFRYERPQKGRYRQFYQLGVEAYGFDGIAIDLEVIAIAWSLFKELGISEYVTLELNSLGSSLNRQEYTQALLQYLKPYHAELDEDSIKRLDKNPLRILDSKIEKTQKILANAPKLIDFIDHDLRLRFKQTCQYLDALGVRYKLNENLVRGLDYYTGLVFEWTTDKLGSQSAICAGGRYDGLVENLGGQKIAAIGFAIGMERLLLLLEDLGKLPNQDNACDVFFILDSAQLHQSLAIVENIRQELPQLKIDMDLKFGSFKSQFKKADKSGAKVAIIIGQDELDNGFAGIKFLQQNEEQQQVAFNELINFLER
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_WOLPM
Sequence: MNKELLDDILSLEDKAVSEIENASSLQDLEKVRLSYLGKKGVIKAYFDNLKEIEDAGKKRNLGEVINVLRNKLDQLIMSKENILKAEEVNFKLQNEAVDITLSARPEKIGKVHPLSKVLNEVKLIFAHMGFKAVDGPDIEDEFHVFDALNTPSHHPAREEQDTFYLKNKIDDKRMVLRTHTSSVQIRTMEKTKKFPIKIVAAGRVYRNDFDATHTPMFHQIEGLYVDENVNMGQLKFTIHHFLNKFFGDKGLKIRFRNSFFPFTEPSAEVDISYKGSKWIEVLGCGMTHPNVFQNVGIDHTKYNGFAFGIGIERLAMLKYQISDLRSFYDNKISWLDHYGFHFSSLR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK13_PANTR
Sequence: MSLIRKKGFYKQDVNKXXXELXKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMXFMQTDLQKIMXMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDXAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRRXGXKL
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.  Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.  MAPK13 is one of the less studied p38 MAPK isoforms.  Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets.  Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.  Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1.  Mediates UV irradiation induced up-regulation of the gene expression of CXCL14.  Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development.  Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway.  MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 13, MAP kinase 13, MAPK 13, Stress-activated protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: SMR1_PODAS
Sequence: MDHRDLSQVTLLMESTLIRTALRTDIQQFEKSFEQIIEQAGVFLATTEEHFISLSLVVMDEDVLIRHLCGFLASKLAIEGFLSFHQQTIQRTSGGDASLAKQVKAATVFVLELIQTLIYHKEAADYPGKHLGMMYDRDVKYFGGTLFHLNPQVNLDEELPELDDYYEDVDELTNYYHGEKLSHPLRQLPGNPWHKFFGNFPETRVEHAADTALFRENPRPGDLTVSIPGTILFLIPEFRQEHEKFRQLMLEHSQLPLPLLLEEARKERVQVIQRRLANVHHGNVEYDSLEPLCRENTDMIPRPEYTLEGNRTFGMQNLTVNSPDLIGDALPEGRIANVASQLEGFPARFLFTNKNK
What is the function of this protein?
Transcriptional activator that is required for post-fertilization events.  It is required for the developmental events that occur in the female organ after fertilization.
What are the official names of this protein?
Sporulation minus regulator 1.
What is the protein family that this protein belongs to?
To N.crassa mta-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YD46_SCHPO
Sequence: MSCRYRICRDIWRGKCIYVFRCLYTNHAVVSWNQTNEVIGLYKANEHKFMNNRKQSHIKNGLVVSYSILYPVGKGRSLRSTGVVLILGPVKEY
What are the official names of this protein?
Uncharacterized protein C22H10.06c.
Protein: RS5_VIBPA
Sequence: MAKEQQVQANDLQEKLIAVNRVSKTVKGGRIMSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMTTIALNEGTLHHPVKGRHSGSKVYMQPAAEGTGVIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATIDALGSMKSPEMVAAKRGLTVEAISE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TBA1C_RAT
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGDDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1C chain, Alpha-tubulin 6, Tubulin alpha-6 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIGB_SHIFL
Sequence: MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAVFPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKCYIREVMTHKEYDFFTAVHRTKGKK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  A probable translation-dependent mRNA interferase.
What are the official names of this protein?
mRNA interferase HigB, Endoribonuclease HigB, Toxin HigB.
What is the protein family that this protein belongs to?
Belongs to the HigB mRNA interferase family.
Protein: MRAZ_LISMO
Sequence: MFMGEYQHNIDIKGRLIVPAKFRELLGDNFVITRGLDKCLFAYPQEEWKKLEEKLQTLPLTKKDARSFTRFFFSGASECELDKQGRINIPSNLLQYADLEKETVIIGVSSRIEIWSKSEWDDVFNEAEESFADLAENMIGFDI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: UXA4_CHLT2
Sequence: XSGDS
What are the official names of this protein?
Unknown protein from 2D-PAGE from elementary body.
Protein: RL7_PROMS
Sequence: MSAKTEEILESLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAAGGDADGGAAEEKTEFDVVLESFDAAAKIKVLKVVRNATGLGLGDAKALVESAPKTVKEGIAKADAESLKKEIEEAGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.