PharMolix/UniProtQA huggingface dataset:
Protein: RIMM_NOVAD
Sequence: MRDRPVTLAAITGAHGVAGEVRLKLFGEGVAALKRYRAFNDSGDGSGLTVVKIKDDGKGGAIARFAEVPDRTAAEKLRGTALTVRRSELPSLPEGEYYHADLIGLPAVSTEGEMLGECIAVENFGAGDVIEIRKADGKKFMVPMKTEAVPEWTDERIVIEAAYADQ
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_LACE2
Sequence: MSAVRIKKGDTVKVIAGKDKGKEGKVLSVNAKNHTALVEGVNMVTKHAKPSAANQQGGILHQEAPIDISNIAYSLKGKETKIGYDFKDGKKVRVAKATGEVID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: OADC_BRASB
Sequence: MTFRARREVLRTILTGERCIHPGSVYDAISIRIAEDLGFELGMFGGSAASLAVLGDPDIALITLTELADQMRRMSRAATLPVLVDADHGYGNAMNVRRTVQELEAAGAAGLTIEDTLLPQAFGAAKPQLISLAEGIGKVKAALEGRGDPALVILGRTGAVSVTSLDDAIARARAYEACGVDGLFFTGITARDQLDAIAAATTLPIVLGGAPEHMSDLGYLAARRVRVALQGHAPIAAATQAVYETLKALRGGAAPKQLKGLPSAELTAQVMREAEVKRRLRVYLEPGS
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: THPR_ECOLI
Sequence: MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHLTLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQLANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFARGRTRYTPLKRWALTQ
What is the function of this protein?
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester (PubMed:25239919).  In vitro, can also ligate 5' and 3' half-tRNA molecules with 2',3'-cyclic phosphate and 5'-hydroxyl termini, respectively, to the product containing the 2'-5' phosphodiester linkage.  This reaction does not require ATP and is reversible (PubMed:6347395, PubMed:8940112).
What are the official names of this protein?
RNA 2',3'-cyclic phosphodiesterase, RNA 2',3'-CPDase, Two-histidine 2',3'-cyclic phosphodiesterase acting on RNA.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. ThpR family.
Protein: RNR_MYCPU
Sequence: MKNLVLQNLKSNKAYSFLEIARINKINPNFNSQLSKALFSLLDQGLIVKNNDGNFIKVNEIKKIQGIFKQSNRNFAFIETADEQSYFVAKAHFNGAINSFEVEAIVYESPFEKDKKYAVVKKILKNTHPEIIGFIKISNGIKYFNAFEESFRSYKFFVDQNIDVEEDDVILVVVEKIVDQKIYVNFVKKVSTLKSNFYQIDIVLEKSKTIIDFPEDVLDESALIEDHVIEKDYQNRKDLRDKLIITIDGEDTKDFDDAIYVEKNKDHFLLSVHIADVAHYVKENSAIDKEALRRATSIYLPHMVIPMLPEKLSNGICSLNPGVDRLVMSIDIFIDFQGNTIKTELYEGIINSKHRLTYNQVNDFYNNKIKLDPNLEKMLNDSLELSKILENYKKDEGYINLEIEESKVILDKEGKTVGIKVIQRGLSEVLIENFMVRANEAVAWKMNKLKLPSIYRVHDNPSIESLVLFEKTLKTLGIDFDTPKITSPKAFSDSFEKIKQNYQIDNFVKLMVLRTMEKAIYSDKNIGHFGLASSYYSHFTSPIRRYPDLQLHRLIKQMVFDKSNLKEKKNHFSLILSDVSVQSSKKEVEAVSIERQINDIKKAEYYESKIGKSLKAQIVSILSFGMFVEFEDKVSGLIHISNLLGEDFQVSEDGLLISSNKTKYKLGQEIDVVVVKVDKNLGKVDVVLEKDYQEYLKKEQAFQAFKKNKFTQDKEKQNGKINYKK
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3380_SHEFN
Sequence: MKLVIVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLIGTLLAQLKGSNDLVAISVDVRNIAEQGKVLQDQLALLENDTEIISFFLNSNDKVLLKRYSETRRLHPLSKNHISLQEAIKLEGRLLEPIAKIVDHYIDTSALNIYELSDQVRQILLGSVDKELVINFESFGFKHGMPTEADFMFDVRFLPNPHWEIELRPFTGLDEPVQEFLGRQPLVNKFIWQIENLFETWMPHLERNNRSYLTIAIGCTGGQHRSVYIADQLAKRFRQGSKHTVNARHRELNISDTNN
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Sfri_3380.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RF3_LACH4
Sequence: MDKELAEKVKKRRTFAIISHPDAGKTTITEQMLLFGGVIRKAGTVKARKTGNFATSDWMEIEKKRGISVTSSVMQFEYKGKRINILDTPGHQDFSEDTYRTLMAVDAAVMVIDSAKGIEPQTKKLFKVVKKRGIPIFTFMNKLDRDGRPPLDLIAELEDLLGIEGVAMDWPIGSGQTLKGLYDVANNRVELYRKDGEDRFLPLNEDGTLPDSEPLSQDPQFQDTLDEIELVKEAGNKFDPEKIALGDQTPVFFGSALTNFGVETFLNSFVDLAPAPESHTVNGDEELSPEDPEFSGFVFKIQANMNPHHRDRIAFVRVGSGEFKRGLDVTLARTGKPIRLNNATEFMSSERVQVSDAVAGDIVGLYDTGNFQIGDSIYSGKRKIVYPPLPEFTPELFMRVTAKNVMKQKSFHKGMNQLVQEGAIQLYRNYQTDEYILGAVGQLQFEVFQFRMKNEYNSEVEMNSIGHRVARWIDPEQLDPRMSNSRNLLVKDRYGNPLFLFENEFAERFFHDKYPDVKLTEKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNB_METMP
Sequence: MILLVSPKDVAEAYEAIEGGADIIDVKNPPEGSLGANFPWVIKETREATPEGMLVSAAIGDVPYKPGTVTLAALGATVSGADYIKVGLYGTRSYQEALDVMKNVTKAVKDAGENKIVVAAGYADAYRVGAVDPLVIPKVARDAGCDVAMLDTAVKDGKTLFDHMDLDLLREFVEETHKYGMKCALAGSIKIEEIPMLKEIGCDIVGVRGAACTQGDRNAGRIQKDLVKEIVKVCRD
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: PETN_PSINU
Sequence: MDTVSIAWAALMVIFTFSISLVVWGRNGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y2433_MARMM
Sequence: MAGHSKWANIQHRKGRQDKLRSKLFSRLSKEISIAAKLGGPDVDANPRLRLAVSNAKGQSMPKDNIQRAIDKASGGDDESFEDIRYEGFGPAGIGVIVEVSTDNKNRAAAEVRTAFAKNGGNLGETGSVAFMFDNVGEIRYPLSKADEDTMMEAAIEAGAEDVASEPGDEDNEGEHVIYTAREDLMEVVGGLSATFEDPSSAKLIWRPQNLIEVTGDKVATLMKMMEMLEDSDDVQNVYANFDISDEDMAQLD
What are the official names of this protein?
Probable transcriptional regulatory protein Mmar10_2433.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX8A_CANLF
Sequence: IHSKPPREQL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DAPE_PARL1
Sequence: MTAPASSPASPYDPLDIAVELIRCPSVTPDEGGALGVLEKWLAPLGFKCERMRFSAEGTPDVDNLYARLGSGHPHFCFAGHTDVVPVGQADAWSVDPFAADIKDGRLYGRGAADMKSAVASFVAAAERISREGFQGSISLLITGDEEGPSINGTRKMLEKLAARNETIDHCIVGEPTSVEKLGDMIKVGRRGSINGWLTVQGTQGHVAYPHLADNPVPRLLEMLRRLDAHVLDEGTDHFQPSNLEVTTVDIGNTATNVIPGSARATVNIRFNDLHTGASLDKWMRGVLDAVTAEMGGSYSFKTSVSGEAFITEPGAFSALIAEAAKEVTGITPELSTTGGTSDARFIRAYAPVVEIGLPNATMHKADENTGVSEIRQLADIYETVLRGYFAGRAS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: GYRA_SHIFL
Sequence: MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_PHOPR
Sequence: MKVRASVKKICRNCKVIKRNGVVRIICIEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TRUB_PYRAB
Sequence: MARDEVRRILPADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: SCIN_STAAR
Sequence: MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
What is the function of this protein?
Involved in countering the first line of host defense mechanisms.  Efficiently inhibits opsonization, phagocytosis and killing of S. aureus by human neutrophils.  Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation.  The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium.  Also prevents C5a-induced neutrophil responses (By similarity).
What are the official names of this protein?
Staphylococcal complement inhibitor, SCIN.
What is the protein family that this protein belongs to?
Belongs to the SCIN family.
What are the subcellular locations of this protein?
Secreted.
Protein: CALU_MOUSE
Sequence: MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNADEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
What is the function of this protein?
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues.  Seems to inhibit gamma-carboxylase GGCX.  Binds 7 calcium ions with a low affinity (By similarity).
What are the official names of this protein?
Calumenin, Crocalbin.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Protein: SECB_ACTP2
Sequence: MAEENQVAAPEEAQTPFELQIQRIYIKDVSFEAPNLPTIFHQEWKPQLGFELDTETKQLDEDLYEVVLHINVSTTLEDSGDTAFICEVKQAGVFTIKGIEGIQLAHCLASQCPNVLYPYARELISSLVNRGTFPALNLSPVNFDALFMDYLQRQEAEQNAEAPAVN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_NITMU
Sequence: MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVIEALAQAAALLTLKTSNVEADENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWKYAARAEVDGRVAAEAELMCTVRPKET
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_ECOL5
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_CHLP8
Sequence: MSDLYRFGISLDRELIEAFDRHIKGQGYQSRSEALRDLIRNELLRKTTAEGGLVAGAIVMTYDHHKRELVNRLIDIQHDFHDLIISTQHVHLDHENCLEVIAVKGNAPDIEKLSSALKVLVGVKHLDLSLSSAD
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: LIGB_ECODH
Sequence: MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: LPXK_AFIC5
Sequence: MREPRFWYGPVSLGSVLLAPIAACYGAVAAARLAREGTRAGCPVICIGNYHVGGAGKTPTTLRLVEILREIGETPVVVSRGYGGTLAGPVRVNETHRAADVGDEPKMMARHVPVIVARDRVEGAELARREGASVVLLDDGFQNPALAKDAAVIVIDAARGLGNRMIFPAGPLRAPLAPQVARTNALIVIGEGHAADDIAQGVVQRGGLVVRAAFVPEESSLARLRGARVLAFAGIGDPGRFFATLAKHGVELASRKEFADHHPFTEAELKALADEAQAGGLTLVTTEKDLARIEGDPALAAYAAQIVPFAVTLRVEDEGALLDFLKARMRRARQARQ
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: NUDK_SALTI
Sequence: MSQTITLIKDKILSDNYFTLRNITYDLTRRNGEVIRHKREVYDRGNGATILLYNSTKKTVVLVRQFRVATWVNGNQDGMLIETCAGLLDNDEPEVCIRKEAIEETGYDVGEVRKIFELYMSPGGVTELIHFFIAEYHDSERASIGGGVEDEEIEVLELPFSRALEMVRSGEIRDGKTVLLLNYLQTSHLMD
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.
Protein: YFG4_YEAST
Sequence: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMNRKRSFEKIVISVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFPCPGTLSRNSECQAERQLYDAYFH
What are the official names of this protein?
Uncharacterized protein YFL064C.
Protein: SBPA_AZOBR
Sequence: MSSSFTTTLAGMAVGMLVLATGTNPTLAQDKPTVGIAMPTKSSARWIDDGNNMVKQFQAKGYKTDLQYAEDDIPNQLAQIETMVAKNSKVLVIAAIDGTTLTDVLQQAKDRGVKVIAYDRLIRGSENVDYYATFDNFQVGVLQGSYIVDALGLKDGKGPFNIELFGGSPDDNNAYFFYNGAMSVLQPYIDSGKLTVGSGQVGMDKVSTLRWDGATAQARMDNLLSAFYGNRRVDAVLSPYDGISIGIISSLKGVGYGSPSQPMPVVTGQDAEVPSIKSILAGEQRATVFKDTRELARITVEMVDAVLGGGTAVNDTKTYDNGKKVVPAYLLKPVSVDASNWKGTLVDSGYYTEAQFK
What is the function of this protein?
Mediates chemotaxis towards D-galactose, L-arabinose and D-fucose but not towards D-fructose.  Probably part of a binding-protein high affinity uptake system.
What are the official names of this protein?
Multiple sugar-binding periplasmic protein SbpA, Sugar-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RIMM_ROSCS
Sequence: MEDRPSADEVLLIGTVVDAFGLHGEIKVRSVTDRVDHLRHHVQTVFVGEERRPFPLQRIREPKTGVLILTLGGVTDRTMAEALRGAEVTIRECDAAPLEADEYFIHQLYGLRVVESSGAEIGIVREVLQTGANDVIVVERHGRSDTLLPMIHDVVESLDVAAGQIVVRLLPGLIDEEG
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4764_RHOPT
Sequence: MSSTLPDPHLDQLFVQARTHNAWTSKPVTDDTIHALYDLLKWAPTAANSNPGRFVFVRSAEAKARLLKSVAPGNVDKVKAAPCCVIVAYDTEFHDLLPQLFPARDMRSGFVGKPELITETAKRNSALQGAYLILAARALGLDAGPMSGFDHVALDAEFFPDGRWKSNFLCNIGYGDAEKLFPRNPRLAFEDACRVL
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase Rpal_4764.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: HTPX2_METAC
Sequence: MKRKWERDLGLQGRMLFTMFLLAAVYLFFLAFLSYSGTPPVFMLLFVGAFMGIQYFYSDKMVLWTTGAHIVSESEAPQLHDMVTRLCVIADIPKPQIAIVQTRVPNAFATGRSPNKAVVAVTTGIMDKLTPAELEAVLAHELSHVKNRDMAVLTIASFISTIAFYIVRYSLYFGGMGGDRRRDGGGILLVWLVSIAVWVVSFLLIRALSRYREFAADRGSAIITGQPANLASALMKISGLMDRVPSEDLRKVEGMNAFFIIPAISGSSFMDIFSTHPSVEKRLAQLEKMQKEMS
What are the official names of this protein?
Protease HtpX homolog 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCPMH_TRICW
Sequence: MTRKNVLLIVVDQWRADFIPHLMRAEGREPFLKTPNLDRLCREGLTFRNHVTTCVPCGPARASLLTGLYLMNHRAVQNTVPLDQRHLNLGKALRAIGYDPALIGYTTTTPDPRTTSARDPRFTVLGDIMDGFRSVGAFEPNMEGYFGWVAQNGFELPENREDIWLPEGEHSVPGATDKPSRIPKEFSDSTFFTERALTYLKGRDGKPFFLHLGYYRPHPPFVASAPYHAMYKAEDMPAPIRAENPDAEAAQHPLMKHYIDHIRRGSFFHGAEGSGATLDEGEIRQMRATYCGLITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHGEQLGDHHLLGKIGYNAESFRIPLVIKDAGQNRHAGQIEEGFSESIDVMPTILEWLGGETPRACDGRSLLPFLAEGKPSDWRTELHYEFDFRDVFYDQPQNSVQLSQDDCSLCVIEDENYKYVHFAALPPLFFDLKADPHEFSNLAGDPAYAALVRDYAQKALSWRLSHADRTLTHYRSSPQGLTTRNH
What is the function of this protein?
Hydrolytic enzyme with a broad substrate specificity acting on phosphate diesters and phosphonate monoesters (PubMed:8824203, PubMed:20133613).  Hydrolyzes phosphate mono- and triesters, sulfate monoesters and sulfonate monoesters (PubMed:20133613).  Hydrolyzes glyphosate monoesters.  Does not hydrolyze DNA or cGMP (PubMed:8824203).  Hydrolyzes glyceryl glyphosate, but this substrate has a much lower affinity than the glyphosate monoesters (PubMed:8824203, PubMed:8771792).
What are the official names of this protein?
Multifunctional alkaline phosphatase superfamily protein PehA, Phosphodiesterase, Phosphonate ester hydrolase, PEH, Phosphonate monoester hydrolase, BcPMH, Sulfuric ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase superfamily.