PharMolix/UniProtQA huggingface dataset:
Protein: CGIA_ZOBGA
Sequence: MKLQFKPVYLASIAIMAIGCTKEVTENDTSEISEVPTELRAAASSFYTPPGQNVRANKKNLVTDYGVNHNDQNDDSSKLNLAIKDLSDTGGILTLPKGKYYLTKIRMRSNVHLEIEKGTVIYPTKGLTPAKNHRIFDFASKTEEKIENASIVGKGGKFIVDLRGNSSKNQIVADVGNVTNFKISNFTIKDEKTIFASILVSFTDKAGNAWPHKGIIENIDQANAHTGYGLIQAYAADNILFNNLSCTGGVTLRLETDNLAMKTAKKGGVRDIFATKIKNTNGLTPVMFSPHFMENGKVTIDDVTAIGCAYAVRVEHGFIEIFDKGNRASADAFKNYIEGILGAGSVEVVYKRNNGRTWAARIANDFNEAAYNHSNPAVSGIKPGKFATSKVTNVKATYKGTGAKLKQAFLSYLPCSERSKVCRPGPDGFEYNGPSLGVTIDNTKRDNSLGNYNVNVSTSSVQGFPNNYVLNVKYNTPKVCNQNLGSITSCN
What is the function of this protein?
Hydrolyzes iota-carrageenans, sulfated 1,3-alpha-1,4-beta galactans from red algal cell walls, with an inversion of anomeric configuration.  Also active against hybrid iota-/nu-carrageenan, not active against kappa- or lambda-carrageenans.
What are the official names of this protein?
Iota-carrageenase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 82 family.
What are the subcellular locations of this protein?
Secreted.
Protein: JZT32_CHIGU
Sequence: KASVLITLAVLGVMFVWTSAAELEERGSDQRDSPALIKSMAKVFQSEERECTKLLGGCTKDSECCPHLGCRKKWPYHCGWDGTFGK
What is the function of this protein?
Inhibits TTX-sensitive and TTX-insensitive sodium currents (IC(50) is 0. 6 uM and 0. 95 uM respectively) on rat dorsal root ganglion (DRG) neurons (PubMed:18581053, PubMed:19409400).  Inhibits muscular subtypes sodium channels Nav1. 4/SCN4A and Nav1. 5/SCN5A transiently transfected in to HEK293 cells (IC(50) is 5. 42 uM and 0. 45 uM respectively).  Also blocks Kv2. 1/KCNB1 potassium channels expressed in X. laevis oocytes with an IC(50) of 604 nM.  Injection of the toxin in mice was immediately followed by general ataxia, lack of response to stimuli and semiparalysis (PubMed:19409400).
What are the official names of this protein?
U18-theraphotoxin-Cg1a, U18-TRTX-Cg1a, Jingzhaotoxin-32, JZTX-32, Jingzhaotoxin-9, JzTx-9, Jingzhaotoxin-IX, JzTx-IX, Peptide F6-16.24.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 47 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAD_BACSU
Sequence: MNHETFLKRAVTLACEGVNAGIGGPFGAVIVKDGAIIAEGQNNVTTSNDPTAHAEVTAIRKACKVLGAYQLDDCILYTSCEPCPMCLGAIYWARPKAVFYAAEHTDAAEAGFDDSFIYKEIDKPAEERTIPFYQVTLTEHLSPFQAWRNFANKKEY
What is the function of this protein?
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
What are the official names of this protein?
Guanine deaminase, GDEase, Guanase, Guanine aminase, Guanine aminohydrolase, GAH.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RF3_HALHL
Sequence: MQDVATEAAKRRTFAIISHPDAGKTTLTEKLLYYGGAIQMAGSVKGRKSKAHATSDWMAMEQERGISVTSSVMQFPYRERILNLLDTPGHGDFSEDTYRTLTAVDSALMVIDIAKGVEERTVQLMDVCRMRDTPITTFINKLDRDGRDPVEVLDEVESVLRIRCAPVTWPLGMGRGFRGVYHLHLDQVRLFMDREIIQGLDNPRLDELFPGEVDEWREQIELVREASDSFDPEAYLAGQLTPVYFGSAVNDFGIRELLDDFVEHAPAPRSRDAGREVRADEENFTGFVFKIQANMDPQHRDRIAFLRVCSGRFEPGMKLYQVRTGKNMKIPRATTFMASDRSHAETAAPGDIIGIHNHGTIIIGDAFTEGESLHFTGIPDFAPELFRRVVLRDPMRMKALQKGLEQLCEEGATQLFRPLLGSDWIVGAVGTLQFDVAAYRLQKEYGVECTFEGVQVYTARWVSAEDEKALQRFRDRNESALAWDGTGALAYLAPTRANLELTQERWPDIRFLATRDR
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_ECOLC
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_POLSJ
Sequence: MSQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENVQGEVQKKLDIIANEVLIEANEWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAGYCVYGPQTTLVLTVGDGVAMFTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFNMRWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGKQRILDIQPGKLHERVSVILGSKNEVERVTGYHSGL
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDH4_YEAST
Sequence: MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE
What is the function of this protein?
Potassium-activated aldehyde dehydrogenase involved in acetate formation during anaerobic growth on glucose.
What are the official names of this protein?
Potassium-activated aldehyde dehydrogenase, mitochondrial, K(+)-activated acetaldehyde dehydrogenase, K(+)-ACDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CAS2C_THEYD
Sequence: MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: DAPA_SALTI
Sequence: MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVANGTSAIVSVGTTGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIIAIKEATGNLTRVHQIKELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAARDMADMCKLAAEGQFAEARAINQRLMPLHNKLFVEPNPIPVKWACKALGLVATDTLRLPMTPITDHGRDIVKAALQHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1849_NITEU
Sequence: MQVIIISGLSGSGKSIALKVLEDSGYYCVDNLPASLLVVLINHLQTQQHAYVAVAIDMRSGENITVLPWQLKMIDKSIQIKFIFLEARTETLMQRFSETRRRHPLSDKNITLEEAIRREREALATLTGLGHHIDTSSLRPNVLRAFIKDFIADSRSPSQLTLLFQSFGYKHGIPLDADLVFDIRCLPNPFYDPQLKELTGHDPEVIRFMESQPDASKMLRDISSFLGTWLPAYIRDNRAYLTVAIGCTGGQHRSVYFAEKLALHFHDSAHVLVRHRGLAEYKPHYARR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein NE1849.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: GRXS8_ORYSJ
Sequence: MDRVTRLASQKAVVVFSKSSCGMSHAVTRLLRELGVDARVVELDEEPAGADMENALAGMLLAGTAANGGGRGRGVVVPTVFIGGRLVGSTDRVMSLHVAGGLVPLLRDAGALWV
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S8.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_THEPX
Sequence: MAIQIVLIVGPTASGKSKLAVDVAKEFNGEIISADSMQVYKYMDVGTAKITKEEMQGIPHYLIDIVEPDQEFSVAEYEKRAKEIIKDIYKRGKLPIIVGGTGLYINSIIYIMHFSDFEGSKEFREKMKELANTYGSQYLYEKLKSVDPEAAKKIHPNDIRRIIRALEVYEFTGKPISYYQKMSGMRLNPEYQPIMIGLNFRDRQILYDRINQRVDEMIKNNLVEEVVNLLKIGYNKDSTAMQALGYKEIVEYLKGEISLEEAIEKIKKGTRRYAKRQITWFKGYDFIKWFFVDDYKNYEELKKNIIKYLAGKLNF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CPSD_STREE
Sequence: MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVNPGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADLSHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVIDAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVFNKLDISVDKYGVYGFYGNYGKK
What is the function of this protein?
Involved in the regulation of capsular polysaccharide biosynthesis.  Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation.  May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.
What are the official names of this protein?
Tyrosine-protein kinase CpsD.
What is the protein family that this protein belongs to?
Belongs to the CpsD/CapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGF11_DROMO
Sequence: MSASNATHTHLSSSGGASQMATTQGHLTASAITLNFRELIKEPKGLEDAANYLFQGLLDDVVAGIFIEIHHLRKTGNLTALDGVGEENAESAYRICEMPNLDIFGISTAKKPMDCTCPHCDRLVAAARFAPHLEKCMGMGRISSRIASRRLATKEGASASSSSTSTYIQSGGNTGGTDDEDDVDWSSDKRKKKSTQNSRNNGSKKNNGKIF
What is the function of this protein?
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  Required for nuclear receptor-mediated transactivation.  Binds independently on SAGA to promoters in an RNA-dependent manner.  Binds to mRNA and is essential for total mRNA export from the nucleus.  Required to counteract heterochromatin silencing.  Controls the development of neuronal connectivity in visual system by being required for accurate axon targeting in the optic lobe.  Required for expression of ecdysone-induced genes such as br/broad.
What are the official names of this protein?
SAGA-associated factor 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Localizes to nuclear periphery, in contact with the nuclear pore complex (NPC).
Protein: SECA_ECOHS
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTVEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TIF7_ARATH
Sequence: MERDFLGLSDKQYLSNNVKHEVNDDAVEERGLSTKAAREWGKSKVFATSSFMPSSDFQEAKAFPGAYQWGSVSAANVFRRCQFGGAFQNATPLLLGGSVPLPTHPSLVPRVASSGSSPQLTIFYGGTISVFNDISPDKAQAIMLCAGNGLKGETGDSKPVREAERMYGKQIHNTAATSSSSATHTDNFSRCRDTPVAATNAMSMIESFNAAPRNMIPSVPQARKASLARFLEKRKERLMSAMPYKKMLLDLSTGESSGMNYSSTSPT
What is the function of this protein?
Repressor of jasmonate responses.  Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY7/JAZ9 interaction (PubMed:19151223).  Interacts with and suppresses RHD6 and RSL1 transcription factor activities to negatively regulate jasmonate-stimulated root hair development (PubMed:31988260).
What are the official names of this protein?
Protein TIFY 7, Jasmonate ZIM domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCX8_CYAPA
Sequence: MGLNYNQEDFMGLDRFFQDAVSHNNTDANAASSIEVEMYECDCMYPTFAEIARRSGQPEIGAMFDAIAKEEGMHAQLLTKLYSELEVKDSAETLEAKRLVSTIESQIDAVASDSRGLRRALETALEVETIESQKTYPAFAKLAAEQGNMEVATAFEAIVKSETKHANWVKRALENLLEVA
What are the official names of this protein?
Uncharacterized protein in petA-psaM intergenic region, ORF180.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: DRE2_MAGO7
Sequence: MSPATVTIDTTPDFSNGGAPHSTLLLAPPAMAAQQDAMAAALTDAAPLGSRPELYMLDRLAAGLTNLAPAAYDLVLVLASGADPLLSRRDVFAKIADAMKPGAKLRSRDGSPLDAAIAKEAILAGLVESAEGAYEKPAEEVAAVPLKFLKKKNKGEGGGPVQSPAAATQPTAPAPAAAAKSLPNGVVMVDLNDDFDVSDDEMIDEDELMTEEDLMRPIQQPPECAPKPGKKRRACKDCTCGLAERLEAQDKARRDKADKQLQEKAATPFKLASEDLNELDFTVQGKTGSCGSCALGDAFRCADCPYIGLPAFKPGEEVTILNNVAQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: BTUC_CITK8
Sequence: MENMLTFACQQQRRNVRWLSSLSVLMLLAVVLSLCAGDQWIAPGDWFSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPGWALGFCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSAMMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQAWLMIALIPVSLWICCQSQPMNILALGETSARQLGLPLWFWRNLLVVATGWMVGVSVALAGSIGFIGLVIPHILRLCGLSDHRALLPGCALAGAIALLLADVIARLALASAELPIGVVTATMGAPVFIWLLLKSRR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KVD26_HUMAN
Sequence: MRLPAQLLGLLMLWVPGSSAEIVMTQTPLSLSITPGEQASMSCRSSQSLLHSDGYTYLYWFLQKARPVSTLLIYEVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDFGVYYCMQDAQDP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2D-26.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: GNL3_DANRE
Sequence: MKRPKLKKASKRLSCAKRYKIQKKVREHNRKLKKAAKKQGISRKAKKDIGVPNSAPFKEEVLREAEQRKQELETLKEQNKIVKQQEKAAKRKKEKDAASSVKEPAAKKAKKAAKIKEARAAIVKVKSAKTFKCQELNKVIEASDVIVEVLDARDPLGCRCPQLEEMVLKHEGKKKLLFILNKIDLVPKDNLEKWLHFLEAECPTFLFKSSMQLKDRTVQQKRQQRGTNAVLDHSRAASCFGKDFLLQTLNDLANKKEGETMLKVGVVGFPNVGKSSIINSLKEMRACNAGVQRGLTRCMQEVHITKKVKMIDSPGILAALSNPGSAMALRSLQVEEKEESPQEAVRNLLKQCNQQHVMLQYNVPDYRSSLEFLTTFAMKHGLLQKGGVADTELAATTFLNDWTGAKLSYYSRVPERQGLPSYLSDAIVTELQSDVDMDAVKKGNENVKRSVRFPNLASCISFDSSGPTAGVLDVSELPKEILTKAATTTDAEEEKMDTTTNTDEPEAESHISSTVEPIQEPTEKRKDKPAKEVKFVPVNTDLTSMQNKNNEDAYDFNTDFV
What is the function of this protein?
May play a role in regulating cellular proliferation.
What are the official names of this protein?
Guanine nucleotide-binding protein-like 3, Nucleostemin-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus.
Protein: RL1_CLOD6
Sequence: MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEAHIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQKIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAGKVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASSMGPGVKINPARTAE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YJ31_YEAST
Sequence: MMLSLRRFSMYVLRSLRLHFKKIIITLLTIQLLFITIFVLGGRSSIIDGNWKSFMALFFKPLAYTNRNNNHASFDLRSKDNVAKLYEKMNFDTSGKWIDTYTLKNNLLTVKMGPEKGQVLDSVDELRYYDNDPRLVWSVLLDHLLESDSNEYAFSWYDWANFDSTNKLIALRHTNISCQFVCEGAFDKNVLEMVESEVQEPLFVTNRNKYDESLWYNRVRKVVDSNSVQQAIHDHCMNNDAYSNGTPFELPFIISEISERLRPEVYDLQAKNHLLYSNFTPLSLTVLDSDKDAYRINLKTTDSSKSNIVQTNLLQNYIKRHRNEMVNGDLIFNHTSMFEKFLHHGSTKKRKLDVEALDKTIYAGEYLELSPSDFQFNAKERIIELETRLRSEGLPSHDTHYLRSLKTSVNTSPALQQKYFAEASDITDATADGHHRDRRFFSIGHNLLNDPQEFEARLNSLIRNFQKFVKANGLISWLSHGTLYGYLYDGLKFPWDVDHDLQMPIKHLHYLSQYFNQSLILEDPREGNGRFLLDVGSAITVGVHGNGENNIDARFIDIDSGIYIDITGLSVSSDAAKQYMSKFVEEESSGESFSALIEDYKFDENDYFDEVDGREGLAKYTIHELMEWVNSHPDDFTDAEKNLVTKTYKKELAISRSDYAEKDLSPKQRYLVNEKYNLYNCRNQHFSSLNIISPLRNTMFSGVSAFVPNRPIATLNNEYKVPAKYGLLSFQGKVYLPEFRYWFSFADMKKFANLQLKEPKITRLESPLNDLKFSDISLLITNILKCGFHSVFASLFNSFDSTVYRLKELEIQYDPSLSEEEKSSLLKTLRRGMSKKIKSPEKDPIIYIYERKLWENVEKLLNASNIYNIASQVEKEKGKEFVERSQQVYERNFDGFRLPDGGNSKTVNDLNSKGLNLFGDNKKTSNNIFGSDQKY
What are the official names of this protein?
Uncharacterized protein YJR061W.
What is the protein family that this protein belongs to?
To yeast MNN4.
Protein: EPTA_ECO57
Sequence: MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDRSMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGANILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHRPTYYNRYPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE
What is the function of this protein?
There are several lipid A forms in this strain, including a phosphoethanolamine (1-O-P-pEtN) form; overexpression of this gene leads to higher levels of the 1-O-P-pEtN form of lipid A.
What are the official names of this protein?
Phosphoethanolamine transferase EptA, Polymyxin resistance protein PmrC.
What is the protein family that this protein belongs to?
Belongs to the phosphoethanolamine transferase family. EptA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_PHOPR
Sequence: MTALEMQLTELLEASVNASGYELVGLEFIRAGEHSTLRVFVDHENGINVEDCAEASRQISAVMDVEDPITVAYHLEVSSPGLERPLFKAAHYQQFVGHEVNLVLKMAMNNRRKWKGDIVAVEGELITLKVDGNDETFALSNISKANLIPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_XYLFM
Sequence: MNIPPYRTRIKFCGMTRVGDVRLASELGVDAVGLIFASGSSRLLTVSAACAIRRTVAPMVNVVALFQNNSADEIHTVVRTVRPTLLQFHGKEEDAFCRTFNVPYLKAIPMAGAEAKRICTRTLYLKYPNAAGFIFDSHLKGGTGQTFDWSRLPIDLHHPFLLAGGITPENVFDAIAATVPWGVDVSSGIELQPGIKDGDKMRQFVEEVRRADGRRQFGVA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.