PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_RHIEC
Sequence: MSESRTSADGGMETSYGFREVPGGEKQGLVNQVFHKVAKRYDIMNDVMSMGMHRAWKDAMIAALNPRKEPGYKVLDVAGGTGDIAFRIVEASGRQAHATVLDINGSMLGVGAERAEKKKLSGNLTFVEANAEELPFEAASFDAYTIAFGIRNVPRIDKALSEAYRVLKRGGRLLVLEFSEVDMPLLDKIYDAWSFNAIPQFGKAITGDAEPYQYLVESIRKFPNQENFAAMIRQAGFSRVTYTNYTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SPD21_HUMAN
Sequence: MDRTETRFRKRGQITGKITTSRQLHPQNEQSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPCRSLGWKRKKEWSDESEEEPEKELAPEPEETWVVETLCGLKMKLKQQRVSPILPEHHKDFNSQLAPGVDPSPPHRSFCWKRKREWWDESEESLEEEPRKVLAPEPEEIWVAEMLCGLKMKLKRRRVLLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIVYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYGKTRSRIPLLRKRWFQLGRSMNPRARKNRSRIPLLRKRRFQLGRSMNPRARKYRSRIPLVRKRRFQLRRCMNPRARKNRSQIVLFQKLRFQFFCSMSGRAWVSPEELEEIQAYDPEHWVWARDRAHLS
What are the official names of this protein?
Putative speedy protein E21.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: FLS1_ARATH
Sequence: MEVERVQDISSSSLLTEAIPLEFIRSEKEQPAITTFRGPTPAIPVVDLSDPDEESVRRAVVKASEEWGLFQVVNHGIPTELIRRLQDVGRKFFELPSSEKESVAKPEDSKDIEGYGTKLQKDPEGKKAWVDHLFHRIWPPSCVNYRFWPKNPPEYREVNEEYAVHVKKLSETLLGILSDGLGLKRDALKEGLGGEMAEYMMKINYYPPCPRPDLALGVPAHTDLSGITLLVPNEVPGLQVFKDDHWFDAEYIPSAVIVHIGDQILRLSNGRYKNVLHRTTVDKEKTRMSWPVFLEPPREKIVGPLPELTGDDNPPKFKPFAFKDYSYRKLNKLPLD
What is the function of this protein?
Catalyzes the formation of flavonols from dihydroflavonols.  It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin.  In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol.
What are the official names of this protein?
Flavonol synthase/flavanone 3-hydroxylase, FLS 1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KDPA_BORBR
Sequence: MNADFLGLLLLYLAILLCAAPLLGRHIRQAMNGERTWLTAWGQPLERGLYRLAGVDPAAEMDWRRYAVAMLVFNVLGVLAVYALQRLQGWLPLNPAGLPGVAPDSALNTAISFVTNTNWQGYAGESTMSYLTQMLALTVQNFVSAATGIAVLIALVRGLARHSAATLGNFWADLVRATLYVLLPLSFILALALVSQGVVQNLDPYVEAQTVQAQQYETARLDAQGQPMTGPAGQPLTDTVVTRVQNLPMGPVASQEAIKLLGTNGGGFFNANSAHPYENPNAWSNLLEMLAILLIPAALCWTFGEMVGSRRQGVAILAAMTVLFAGFSASAAYFEQQPTPALRQAEAALLADGGNLEGKEARFGVAATALFATVTTAASCGAVNGMHDSFSALGGVTPLLQMQLGEVIYGGVGSGLYGMLAFAILAVFIAGLMIGRTPEYLGKKIEALDMQMVALVILATPALVLAGTAVAVLADAGRAGVLNPGAHGFSEILYAMSSAANNNGSAFAGLSANTPFYNVLLGLAMWFGRYTIIVAILALAGSLAAKPRLPASVGGMPTTGPLFVALLVGAVLLVGALTYVPALALGPVAEHLQP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYF_OLTVI
Sequence: MFTNNLTKNALVTLVSGFMAIFIGFNTVQPAEAYPIFAQQNFKNPREANGRIVCANCHLAQKPVELEVPQAVLPDTVFEATVKVPYDKSIKQVGANGKPAELNVGAVLILPEGFQLAPSDRIPEEMKTKVGNLYFSPYSTEQKNILVVGPVPGKDYSEMVFPILSPDPAKDKSVSYLNYPVYLGGNRGRGQVYPDGSKSNNNVFGSPVAGTVSEIKALKSKKGGYEVTITTASGNTVVEKIPGGPEVIVSEGEVVTVDQPLTNNPNVGGFGQGEAELVLQNPARIQGLLLFLLATIGAQVFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HSLV_AGRFC
Sequence: MTTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRIGKGEVIAGFAGATADAFTLLDRLEKKLEQYPGQLMRAAVELAKDWRTDKYLRNLEAMMLVADKSTTLAITGNGDVLEPEHGAIAIGSGGNYAFAAARAMMDTDKSAEEVARQSLDIAADICVYTNHNLVVETLDAE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPGP_ECOSM
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREGNVPVILCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQFTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPTRVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_ECO8A
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPIKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GPI_THEGJ
Sequence: MEYKRPFGVKIDLETGVIPGAKRIVRKLSDMRGYFVDEEAYEKLLREDPVVYEVYAIEQEEREGDLNFATTVLYPGKVGKEFFFTKGHYHAKADRAEIYYALKGKGGMLLQTPEGEAEWIPMEPGTVVYVPPYWAHRTVNTGGEPFVFLAIYPADAGHDYGSIKEKGFSKIVIDEGGEVKIVDNPRWSV
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_RHILO
Sequence: MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFKELSPDAKGGVRLAKSVADVVANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYLSILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAIDPERGVTADDVKKLNAALKLDGDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVLELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITKDPAVKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLEGTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: G6PI2_CLAXA
Sequence: MATPSLISETEAWKDLKAHLEGIKRTHLRELMGDTERCQSMMVEFDNIFLDYSRQQASPDTINKLYKLAEAAHLKQKIDRMYNGDHINSTENRSVLHVALRAPRNSAICSDGKNVVPDVWNVLDKIKDFSERVRNGSWVGATGKELKDVIAVGIGGSFLGPLFVHTALQTDPEASKNARGRELRFLANVDPIDAARNISGLNPETTLVVVVSKTFTTAETMLNARTLREWISSALGVSAVAKHMVAVSTNLPLVEKFGIDPNNAFAFWDWVGGRYSVCSAVGVLPLSLQYGFAVVEKFLQGAHSIDQHFSSAPFEKNIPVLLGLLSVWNVSFLGYPARAILPYSQALEKLAPHIQQVSMESNGKGVSIDGLPLPFESGEIDFGEPGTNGQHSFYQLIHQGRVIPCDFIGVVKSQQPVYLKGEVVNNHDELMSNFFAQPDALAYGKTPEQLKKENVSEHLIPHKTFTGNRPSLSILLPTLDAYRIGQLLAIYEHRVAVQGFVWGINSFDQWGVELGKSLATQVRKQLHASRVKGEPVEEGFNFSTKTLLTRYLEATSDVPADPSTLLPKI
What are the official names of this protein?
Glucose-6-phosphate isomerase, cytosolic 2, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SALPK
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMMHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: GCY22_CAEEL
Sequence: MSFISKCFICLLFSTYFLPPVNSAVLQVGFLAANDNTTELAPFIGWGQVAGALGVAWSRIVEYGLLPGYETMNLTWVLTNCREADAVGSVINYAEGHAHVVLGPPCVRPAQVAGSVAKYLDFPLILWGPPFDSSLLNQFEYPTIASTTSSTLYQATSLIRLLEYYKWTEIALIYYVARSDLIPRCTPLISDFEGLVNNNDNLTITYRRQMSVITNTSYATALRNLKELARVVIVCLESDEARRNLMISISENGMDGDEYVYIMAESRRAGFASSFWNGTDGKNDLALRAARKFLVMDNQKYNDTTTFVQEVRAAFSRPPFSCPNCTNIDPTVSQVGPLGDALLLYAYALNRSIATGNPNPTGTEFCEVAKGMEFLGFTGKVIINQNSTRTPLFVVYNLDSTDKEMIVMQITEDLDDSKDPVASSVNYYITLVATPAQIWDTWGGTVPLSTPICGFTGTDCPKSFTDQYLAIILGCTAAALVLIIAVISTIVFLVRSKRQEEERLNQLWQVHFSSLVKPPQKNTMHSSRSLQSTVTTSTKVTINSKKDTERHSFYFLNNDSVVARKHNFRATFTKNDRAMFRKMRNVDNDNLCKFIGLSLDSPTLISIWRYCSRGSLQDVIAKGSLQMDWFFKYSLMRDVADAIYYLHHSPIGPHGWLSSSTCLVDERWQVKVSFFGLSAIKQYEVKEQRDFLHTAPEHIRDTNLPITKEMDIYSFAIICSELITKKSAWDLENETFDIEELVYKIKKGGRSPPRPSLETEDEHNGSMSLLVRDCWNENPDQRPTSEQIKTLMKSMNHNRSSNLMDHVFNVLEQYASNLEDEVQARMKELTEEKKRSDVLLYRMLPKQVAEKLKLGQSVEPETFDCVTIFFSDVVSFTTLASRCTPLQVVNLLNDLYTTFDAIIEQHDVYKVETIGDGYLCVSGLPHRNGNEHAKEISSMSFSLLKAIKTFRVPHLPKERINIRVGLHTGPVVTGVVGMTMPRYCLFGDSVNTASRMESNGKPGRVHISTECMKFLTEVIGGYQTEPRGEVIVKGKGAVQTHWLLTDDEIEAKENGESI
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Regulates chemotaxis responses toward Li(1-), Mg(2+), Cl(1-), Br(1)- and I(1-) salt ions and methionine in ASE right (ASER) sensory neuron (PubMed:19523832, PubMed:20837997).  May regulate ASER neuronal activity such as axon sprouting and calcium responses to changes in salt concentrations (PubMed:19523832).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-22.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NDK_THEKO
Sequence: MADKQIERTLIILKPDAVVRGLMGEIISRFEKRGLKIVGMKMIWIDRKLAEKHYAEHKGKPFFEPLIDYITKAPSVVMVVEGRYAISVVRKMAGATDPKDAEPGSIRGDYGLDVGDAIYNVIHASDSPESAEREINLYFKPEELFEYCKAADWFYHTHARSKKEYLDSMDCLER
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFIP4_HUMAN
Sequence: MAGGAGWSGAPAALLRSVRRLREVFEVCGRDPDGFLRVERVAALGLRFGQGEEVEKLVKYLDPNDLGRINFKDFCRGVFAMKGCEELLKDVLSVESAGTLPCAPEIPDCVEQGSEVTGPTFADGELIPREPGFFPEDEEEAMTLAPPEGPQELYTDSPMESTQSLEGSVGSPAEKDGGLGGLFLPEDKSLVHTPSMTTSDLSTHSTTSLISNEEQFEDYGEGDDVDCAPSSPCPDDETRTNVYSDLGSSVSSSAGQTPRKMRHVYNSELLDVYCSQCCKKINLLNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDSLTNGDLKSKLKQENTQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEIDTASRDELMEALKEQEEINFRLRQYMDKIILAILDHNPSILEIKH
What is the function of this protein?
Acts as a regulator of endocytic traffic by participating in membrane delivery.  Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis.  In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
What are the official names of this protein?
Rab11 family-interacting protein 4, FIP4-Rab11, Rab11-FIP4, Arfophilin-2.
What are the subcellular locations of this protein?
Endosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis.
Protein: RL17_LACP3
Sequence: MSYRKLGRTSSQRKALLRDLTTDLLINERIVTTEARAKEVRSTAEKMITLGKRGDLHARRQAAAYVRNEIASVEEQDDNSVVVKSALQKLFSDLAPKYADRKGGYTRILKTAPRRGDGAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y1088_AQUAE
Sequence: MSSLISRLRKLFKSRNTHDFSNLCKENYQTLLSSEEGKILLGIYHFLSGEPQKAEELLSQVSENSLNSAQGLSDLGLLYFFLGRVEDAERVLKKALKFSDVDDALYARLGALYYSQGKLEEAQHYWERALSLNPNKVEILYNLGVLHLNKGELEKALDLFERALRLKPDFREAEEKKTLILLSLNRIDELVEEYYRELEKNPNEEVYIKLGNTLYTAGRLAEARAVFQEGAEKFPHDPRLKLGLIEVLKEEGRTYQAGTLLKEWLEDTSWVDEEKTPNKDEFLMQMRFRLNELRIQASFLDTAEKDLEKVENKEDYPEYYILKSKILMERNKGLEAADLLREAKERFPAHLGVLQELVHVLTSIGELEEAKEIQSQIVAINPSAVIQQVEMEDYKATDEQIQVLETLLNSPAVPKQTRASAGFVLHKVLEKRKDYDKAFEVLIKANELVKEEINYDWREHRFMIQRTIEVFTPEVVERLKGRGHPSKRPIFVLGMPRSGTTLTEQILGSHSMVYPAGELPFVPKIVNLIPKALQYVGKEPKEWPEAILEFDERLLKSAAQYYLDRVAKLDSEHPRIVDKLPHNFDYVGLILLMFPNAKVIHLKRNDLDVAVSNYQQNFAAKHGTMGFAFDLRWIGHMLNDHRAIMEHWHKLFPGQIYELDYQRLTEEPEEVIRELLEFCELPWEDRVLEYYKTKRPVKTASIKQVRKGIYRSSVEKWRRYEKYLTPVIEILQEGFKKLEDPEIEKYQDKVIPKGLVGYTVG
What are the official names of this protein?
Uncharacterized protein aq_1088.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein sulfotransferase family.
Protein: LRGA_STAA3
Sequence: MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIFCL_HUMAN
Sequence: MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALPH_SPHSX
Sequence: MLKHVAAALLLATAMPVVAQSPAPAAAPAPAARSIAATPPKLIVAISVDQFSADLFSEYRQYYTGGLKRLTSEGAVFPRGYQSHAATETCPGHSTILTGSRPSRTGIIANNWFDLDAKREDKNLYCAEDESQPGSSSDKYEASPLHLKVPTLGGRMKAANPATRVVSVAGKDRAAIMMGGATADQVWWLGGPQGYVSYKGVAPTPLVTQVNQAFAQRLAQPNPGFELPAQCVSKDFPVQAGNRTVGTGRFARDAGDYKGFRISPEQDAMTLAFAAAAIENMQLGKQAQTDIISIGLSATDYVGHTFGTEGTESCIQVDRLDTELGAFFDKLDKDGIDYVVVLTADHGGHDLPERHRMNAMPMEQRVDMALTPKALNATIAEKAGLPGKKVIWSDGPSGDIYYDKGLTAAQRARVETEALKYLRAHPQVQTVFTKAEIAATPSPSGPPESWSLIQEARASFYPSRSGDLLLLLKPRVMSIPEQAVMGSVATHGSPWDTDRRVPILFWRKGMQHFEQPLGVETVDILPSLAALIKLPVPKDQIDGRCLDLVAGKDDSCAGQ
What is the function of this protein?
Alkaline phosphatase with broad substrate specificity.  Precipitates uranium from alkaline solutions.
What are the official names of this protein?
Alkaline phosphatase PhoK, SPAP protein.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_SACS2
Sequence: MPNKYIVVTGGVLSSVGKGTLVASIGMLLKRRGYNVTAVKIDPYINVDAGTMNPYMHGEVFVTEDGAETDLDLGHYERFMDVNMTKYNNITAGKVYFEVIKKEREGKYLGQTVQIIPHVTDQIKDMIRYASKINNAEITLVEIGGTVGDIESLPFLEAVRQLKLEEGEDNVIFVHIALVEYLSVTGELKTKPLQHSVQELRRIGIQPDFIVGRATLPLDDETRRKIALFTNVKVDHIVSSYDVETSYEVPIILESQKLVSKILSRLKLEDRQVDLTDWISFVNNIKGINSKKTINIALVGKYTKLKDSYISIKEAIYHASAYIGVRPKLIWIESTDLESDTKNLNEILGNVNGIIVLPGFGSRGAEGKIKAIKYAREHNIPFLGICFGFQLSIVEFARDVLGLSEANSTEINPNTKDPVITLLDEQKNVTQLGGTMRLGAQKIILKEGTIAYQLYGKKVVYERHRHRYEVNPKYVDILEDAGLVVSGISENGLVEIIELPSNKFFVATQAHPEFKSRPTNPSPIYLGFIRAVASL
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (PubMed:21301086).  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (By similarity).
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NDK6_MOUSE
Sequence: MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRTRELQWKLEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARYIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGHKQPNKT
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 6, NDK 6, NDP kinase 6, nm23-M6.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: Y1094_ARCFU
Sequence: MKVLLDIIEDIENFIRQLEKRRGELEELKDEILIFSDAEFIDSIQRGLSDLEQGRSKVCSNLEEVKKLFEDI
What are the official names of this protein?
Uncharacterized protein AF_1094.
Protein: YC01A_YEAST
Sequence: MTFLQFINNNRQEGQGYISEKLFKTKKNEMIRKTVTNLVAVRLKNLSHEFDVIENYLRYIASTSEHLFTAIKRHFNKCARKLLKEAIDSKSNSETATVVLQEGFSGICLLKASSIILKLKLKFPKKKDRTDISKLCDKKERMTQWLEISILMN
What are the official names of this protein?
Putative pelota-like protein YCL001W-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily. Highly divergent.
Protein: MRKD_KLEPN
Sequence: MKKLTLFIGLMALGTTSAWASCWQSNSAYEINMAMGRVVVSPDLPVGSVIATKTWTMPDNNTIYVTCDRNTTLKSDAKVVAAGLVQGANKVYSTAIPGIGLRFSRKGAISMIYPDSYTTTGSSFRLVGSTFTLDIIKTSTTTGSGTLASGPYTEYGPGFTILKTSLNADAITIVSPSCTILGGKNMNVDIGTIKRADLKGVGTWAGGTPFDIKLECSGGVSVSGYANINTSFSGTLATNTSANQGVLLNEKTGNSAAKGVGVQVIKDNTPLEFNKKHNIGTLQSQETRYITLPLHARFYQYAPTTSTGEVESHLVFNLTYD
What are the official names of this protein?
Fimbria adhesin protein.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: NOX1_HUMAN
Sequence: MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
What is the function of this protein?
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues.  It participates in the regulation of cellular pH and is blocked by zinc.  NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
What are the official names of this protein?
NADPH oxidase 1, NOX-1, Mitogenic oxidase 1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1.
What are the subcellular locations of this protein?
Cell projection, invadopodium membrane; Multi-pass membrane protein. Cell membrane.