PharMolix/UniProtQA huggingface dataset:
Protein: LPXC_ECO45
Sequence: MIKQRTLKCIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: SYGA_XANC5
Sequence: MSDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEITYGLERLCMYLQSCDNVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVGLPLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGVKK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_MYCS2
Sequence: MKQQLVFEAPRRAMPPQHLADLDETARAAAVTELGLPAFRAKQLANQYYGRLIADPQQMTDLPAAVRDQVAEKLFPTLINPVREIQCDAGETRKTLWRAIDGSTFESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLQRNLTTAEILEQVRAASSTMRAEHFGRTAGTAGGGRLSNIVFMGMGEPLANYNRVLGAVRRIIAAPPNGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLHAPDDELRDTLVPVNNRWKVSEVLDAARYYADTTGRRVSIEYALIRDVNDQPWRADLLGKKLHGALGPLAHVNVIPLNPTPGSEWDASPKPAEREFVKRVRERGVSCTVRDTRGREIAAACGQLAAEG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCSD3_KOMXY
Sequence: MTTFNAKPDFSLFLQALSWEIDDQAGIEVRNDLLREVGRGMAGRLQPPLCNTIHQLQIELNALLGMINWGYVKLELLAEEQAMRIVHEDLPQVGSAGEPSGTWLAPVLEGLYGRWITSQPGAFGDYVVTRDVDAEDLNSVPTQTIILYMRTRSNSN
What is the function of this protein?
May have a major role in the perfection of crystallization, involved either in the pore structure itself or in the organization of the pores within the linear array of terminal synthesizing complexes (TCs).
What are the official names of this protein?
Cellulose synthase operon protein D.
Protein: FABH_BARBK
Sequence: MIRSVMCGVGSALPKKKLSNDEIAKFVETSDSWIVQRTGIHQRYIASENETTVSLGIEAAQVALTNAGMTIKDIDCIILATSTPNRTFPSSAVEIQHALGMSHGFSFDVQAVCSGFIFALTIGDVYLRSGEAKRVLVIGSETFSRILDWKDRTTCVLFGDGAGAAILEAREVEGNVAIDRGILSTKLRSNGAHIDKLYADGGPSTTQTIGYLRMKGQEVFKHAVGIVTDVIDDCFAAVGMNPSQLDWFVPHQANKRIIEASAKKLGIKTDKVVITVDQHGNTSAASVPLALATAVQDGRIKEGDLVLLEAMGGGFTWGAVLIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_THISH
Sequence: MRFDGESDYRHGSPEILGVLVTNLGTPDAPTPKALRRYLKEFLWDPRVVEIPRAAWWLILNGIILNVRPRRSAKLYEQVWTEEGSPLLVIGRRQAEGVATRLSERLPGPVKVELAMRYGQPSIESGLMRLREAGARRILVLPLYPQYSGSTGGSTFDQVSRVLRRWRWVPGLRFVSDYHSDAGYLDALAESVRAYWDQHGRGSKLLMSFHGVPKRYLLAGDPYHCQCHATGRQLAERLGLKEGEWVVTFQSRFGKAEWLKPYTDMTVKALGEEKLGRLDVVCPGFSADCLETIEEIAGENREIFQHAGGGEFHYIPALNDNPDHLDALADLVLRNVQGWPEANPGYDATARQSAAEASRARALGMGAKD
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_BLOFL
Sequence: MNNNTYHIAILPGDGIGPEIMQQAYKILNTVKNKFKINIITTEYKVGGNALDLEGSPLPKDTIKNCEKSNAILFGAVGGPKWNNINETSRPEFGALLTLRKHFNLFINLRPIYLPIELINLSPLKPEIISQGLDMICIRELIGGIYFGKPQGKSGIRSQEHAFDTAIYHRFEIERIAHFAFKLAQKRRKHVTSIDKANVLHTSMLWRKVVSEVASNYPNVHLQHLYVDNASMQLIRNPSAFDVILCPNLFGDILSDECAEINGSIGILPSASLNEHNFGLYEPAGGSAPDIAGKNIANPIAQILSTALLFRYSLKLNHVAITIEKAVYKALTLGYRTQDIAYNKQKSVNTDDMGDIIASLIYKL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDCB_DANRE
Sequence: MTHQYPALTAEQKKELQDIAQRIVAPGKGILAADESTGSMAKRLNPIGVENTEENRRLYRQLLFSADERIDKCIGGVIFFHETLYQNTDDGTNFAQLIKDRGIVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRSVLKISDTTPSELAIMENANVLARYASICQQNGIVPIVEPEILPDGEHDLKRCQYVTEKVLAACYKALSDHHVYLEGTLLKPNMVTAGHSCPTKYSSEEIAMATVTALRRTVPPAVSGVTFLSGGQSEEEASVNLNSINNCPLAKPWPLTFSYGRALQASALSAWRGAKSNEKAATEEFIKRAEANGLAAQGKYVSSGTCGAAGQSLYVANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase C-B, Brain-type aldolase-B.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: TATD_CROTZ
Sequence: MFDIGLNITSSQFDHDRDEMIARARAAGVDSMLFTGTSLEESDRACAFARRYAGCWSTAGVHPHDASTWNDESAARLRALASEPEVVAIGECGLDFNRNFSTPAEQEHAFTEQLRLAAALALPVFLHCRDAHARFLALLDPWLDKLPGAVLHCFTGTEQEARECLARGMYLGITGWVCDERRGLELRALLPIIPADRLLLETDAPYLLPRDLTPKPASRRNEPCWLPHILTQVAQWRGEDPAWLEAATDANAARLFLKNASPA
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHR_CERDI
Sequence: MPVQGSQRRLLGSLNSTPTAPPHLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLFSMLFIAYYDHAAVLLCLVVFFLAMLVLMAVLYIHMLVRACQHAQGIARLHKRQRPAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_FRAT1
Sequence: MILIDGKSLSKDLKERLATQVQEYKHHTAITPKLVAIIVGNDPASKTYVASKEKACAQVGIDSQVITLPEHTTESELLELIDQLNNDSSVHAILVQLPLPAHINKNNVIYSIKPEKDVDGFHPTNVGRLQLRDKKCLESCTPKGIMTMLREYGIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKPNFITADMVKEGAVVIDVGINHVDGKIVGDVDFAAVKDKVAAITPVPGGVGPMTITELLYNTFQCAQELNR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL24_SYNWW
Sequence: MRIKKGDSVLVTTGKDAGKKGKVLRVIPDKNRVVIEGVNRVKKHQKPSRSLPQGGILKIETPLNASNVMLVCSRCNKPTRIAHKIMENGEKVRICKQCGEALD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: DOIS_STRRI
Sequence: MQVTPIAMEDASFAYRLGTECTEDVVARLATLGASSYLVVADTTVAGLYGHDLTARIDKEAGPAHLLTHESGEVHKDLTTVSVLAEQALERGADRRSVVVALGGGVTGNITGLMASLLFRGIRLVHVPTTVVAMLDSVLSLKQAVNATFGKNLVGTFYQPVEVLADTAFLRTLPPREIRSGLGEVVKNALAIRPAMLDRLGDALRADARYDDETLRWIIAESLTAKADVTRDDKHERRTGLVLEYGHTAGHAIEHASRGEVAHGAGVAVGMTIAAEVSRRLGHAGPDFVALHRELVAAAGVEPAVPAHVDPALVKNWLAYDNKRGYLDSPPGHTPMVLLSAPGEVLHTGPMPLVPVPLALLEEAVDEAARRGRDAAPAAAYVGPPAAGPLP
What is the function of this protein?
Catalyzes the intramolecular carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose (DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosose synthase, DOI synthase, DOIS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. DOI synthase family.
Protein: CLE7_ARATH
Sequence: MASKALLLFVMLTFLLVIEMEGRILRVNSKTKDGESNDLLKRLGYNVSELKRIGRELSVQNEVDRFSPGGPDPQHHSYPLSSKPRI
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE7p]: Secreted, extracellular space.
Protein: ACPM_MYCLE
Sequence: MAVTQEEIIAGIAEIIEEVTGIEPSEITPEKSFVDDLDIDSLSMVEIAVQTEDKYGVKIPDEDLAGLRTVGDVVTYIQKLEEENPEAAEALRAKIVSENPEAAANVQARLETESK
What is the function of this protein?
Acyl carrier protein involved in meromycolate extension.
What are the official names of this protein?
Meromycolate extension acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMA1_DUNAC
Sequence: MSGKERTEENGAVKQDTKEQVKKSADNGDKGVDEVDFAKIGLEDAFKYLNCSEHGLSGAEAEARLKQHGPNKLPDNSRNPVLVYFGYMWNPLAWAMEAAAIIAIALVDGADFALIVGLLIINATISFVEESNADKAIKALSAALAPKAMALRNGAMVTIDAVDLVPGDVILIRIGNVVPADVKLLPEHGADDYETPVQIDQAALTGESLPAKKFTGNVAFSGSTVKQGERHAVVYATGVNTFFGRAAALISGTHNVANIQRVMNRIGGLCLITIGVWVVIEVPVQFAHYKHSCVAGKEGCPTLLNMLVILVGAIPIAMPTVLSVTLALGAYKLAREGAIVTRMSAVEEMAGLDVLCSDKTGTLTLNKLSIDPSNVFPVGTMDIPEVMKFGALSANIITEEPIDMVLWESYPEREKLKSEYKHTKYFPFNPNDKITIATVLEIATGRVFRVLKGSPQVVLAKAWNAQALDGPVNEKIKEYAGRGFRSLGIAMAEGDGKDGTKWEMLAVLPMFDPPRHDTKETIERCMKQGIAVKMVTGDHLLIGKETAKMLGMGTEMYPSEVLIKARNGDVEAPHGYKNYVAMVEACNGFAQVFPEHKFEIVEILQEAHHRVGMTGDGVNDAPALKKAHVGVAVADATDAARGAADIVLTEPGLSTIVTAVIGARKIFKRMTTYAKYTISVTFRIAFTFGLLTVIYDWYFPTILIVILAVFNDGAMIALSKDRVVASVLPSTWNLATIFVPGFVYAMWLTLSSWALYQVATHSTFFERMTPLPSLNTQHATLISWCEDEISSKLGVNPQDSLCTYPSYADQLNECKGSVSLSSQVPGVPTILDQCVTEQRYIRDALTRALIYTHLSVSGQAVVFVVRTSGFSLKEVAGVSTYVAFALAQFGATMFGIFGLGGYNKPRQNFDNCQFCDYSTHNRVLFFNSEVEPRAGTESVYTASVIGCGGYVIVAWIWAALFYTALDPLKWGLMWIMNDDGFRDRHAWRKSNHEAMERRSREQLDNKEFAGPSGMVPANFSNPLGRASMSKPVSALLDRKSASLVAINRSSMTVSHDPNHALNIGRRSMIGRPSGPLGRNSNTGQSNPLNSSSVEIKPDAPNKV
What is the function of this protein?
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump.  The proton gradient it generates drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
Plasma membrane ATPase, Proton pump.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPL_BACVZ
Sequence: MNLIAAAIAIGLGALGAGIGNGLIVSRTVEGIARQPEAGKELRTLMFMGIALVEALPIIAVVIAFLAFFG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2764_STUS1
Sequence: MNLTAYRDLSPAALRERIRQGEFDGPTAGLANGYAQANLMIVRRELAYDFLLFCQRNPKPCPLLDVTDPGSFEPRHAAPGADIRTDFPRYRIYRNGELDQEVQDITPFWEDDMVAFLIGCSFSFEAALLANGVPVRHIEDGHNVPMYRTNIACQPAGGLSGPMVVSMRPMPANKVVRAVQVTSRFPSVHGAPVHVGDPRLLGIADLAKPDFGEPSELREGEVPVFWACGVTPQAVAMQARPELVITHAPGHMFITDLRDEQLGVI
What are the official names of this protein?
Putative hydro-lyase PST_2764.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: POXB_ECOLI
Sequence: MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR
What is the function of this protein?
A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2).  It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone (By similarity) (PubMed:18988747, PubMed:2663858, PubMed:365232).  The main pathway for acetate production during stationary phase (PubMed:16080684).
What are the official names of this protein?
Pyruvate dehydrogenase [ubiquinone], Pyruvate oxidase, POX, Pyruvate:ubiquinone-8 oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MTNA_BOMMO
Sequence: MSLESIKYTRGSLEILDQLLLPLQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAEIFKERFIGSIEDMLTKDIHDNKAIGSLGCEAILKNIDGDSPVRVLTHCNTGSLATAGYGTALGVIRSLHATKRLEHVFCTETRPYNQGARLTAYELVHEKIPSTLMVDSMVSALMHTRKIHAVIVGADRVAANGDTANKMGTYQIAIVAKYHDVPFYVAAPLTSIDMSLPYGEKIKIEERPDREMTHIGEHRIAAPGINCWNPSFDVTPASLIAGIITEKGVFAPDHLKSVKXHVTGKKYYNIIHI
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMA_METCA
Sequence: MRHVPRKRFGQNFLRDPGVIQEIVAAVGPAPSDRLVEIGPGEGVLTRELLQSGACLEAIELDRDLVAALKRRFAGVGRLRIHEGDAMKFDLRTIATGERLRVVGNLPYNISTPLLFHLFDQIDVIEDMHFMLQKEVVDRLCAGAGDDHYGRLSVMAALYCQAQHLFDVGPECFHPQPKVVSAVVRLVPHAVPPDAGMVKQVSAVVVAAFGQRRKTLRNALKGLLDETAMVRAGIDPGARAEELSLADYVGLSRQLNP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_ECOLU
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_ARATH
Sequence: MLAQSHFFSKSFDLIPPQSPALRSANPSLRISSSYSNSRLSFLSSSAIAVPVSRRRFCLTMASNSKRPNISNESPSELSDTELDRFAAVGNALADASGEVIRKYFRKKFDIVDKDDMSPVTIADQMAEEAMVSIIFQNLPSHAIYGEEKGWRCKEESADYVWVLDPIDGTKSFITGKPVFGTLIALLYKGKPILGLIDQPILKERWIGMNGRRTKLNGEDISTRSCPKLSQAYLYTTSPHLFSEEAEKAYSRVRDKVKVPLYGCDCYAYALLASGFVDLVIESGLKPYDFLALVPVIEGAGGTITDWTGKRFLWEASSSAVATSFNVVAAGDSDIHQQALESLEWH
What is the function of this protein?
Phosphatase required for histidine production.  Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P).
What are the official names of this protein?
Bifunctional phosphatase IMPL2, chloroplastic, Histidinol-phosphatase, Histidinol-phosphate phosphatase, HPP, Inositol-phosphate phosphatase, L-galactose 1-phosphate phosphatase, Protein HISTIDINE BIOSYNTHESIS 7, Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: PG107_VACCW
Sequence: MDKTTLSVNACNLEYVREKAIVGVQAAKTSTLIFFVIILAISALLLWFQTSDNPVFNELTRYMRIKNTVNDWKSLTDSKTKLESDRGRLLAAGKDDIFEFKCVDFGAYFIAMRLDKKTYLPQAIRRGTGDAWMVKKAAKVDPSAQQFCQYLIKHKSNNVITCGNEMLNELGYSGYFMSPHWCSDFSNME
What is the function of this protein?
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.  Also plays a role in cell-cell fusion (syncytium formation).
What are the official names of this protein?
Protein OPG107.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG107 family.
Protein: RL25_CHLFF
Sequence: MELVVTSRETDKKSLLKKIRQTGGIPAVIYSGGKSVANIVVDAHVFSKFLSGLESGALSSTIFSLSYEGRIIRALVKDIQYQVTTYQVIHLDFEELIEDRDVKLNIPIRCINAVDCVGVKLGGSLRQVIRALRVVCKPKDIVPFLELDVRSLGLSQTRKLSDINIPAGLRPITPLKEVVVTVSRR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: DNAK1_SYNP6
Sequence: MGRVVGIDLGTTNSVIAVMEGGKPMVIANAEGVRTTPSVVGVSKTGERLVGELARRQLVLNPRNTFANIKRFIGRRYDELTDESKRVPYTVRRDPEGNVRIVCPQLSREFAPEEVAAMILRKLAEEASRYLGEPVTGAVITVPAYFNDSQRQATRDAGRIAGLEVKRILNEPTAASLAYGLDRRDNQTILVFDLGGGTFDVSVLEVGNGVFEVKATSGDTQLGGNDFDRRIVDWLAEQFLEAEGIDLRRDRQALQRLIEAAEKAKIELSGVSVTDINLPFITATEDEPKHLETRLTRSEFEALCEDLLERMMRPLRRALKDARLQPQDIDEVVLVGGSTRMPMVQQLVRSLIGREPNQNVNPDEVVAIGAAIQAGILAGEVKDILLLDVTPLSLGLETIGGVMKKLIPRNTAIPVRRSDIFSTAENNQTMVEIHILQGERQLAEGNKSLGRFKLTGIPPAPRGVPQVQVSFDIDANGILQVSALDKTTGREQTVTIQGASTLSQEEVKRMMKDAELYAQQDRQLKARIEKRNRAQTLIAQSERRLREISLDFGLYFAESKRRRIESTIRELKDYLERQDDRGLDLALAELQDALFDLNQETAARLRDEEGEGFFEPLKQTFASLRGDGNRDFERSWDDRGGDRWDADPWDRSRRSTPSYGYDDRRSPVSDPYRGERWVEEQTSMSRREPVRDRNGGNGSVRPEPAPRRGRPTWEEDQPPRRDRSSQPPAKPASGRRWNDGWDDDDDEWF
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK 1, HSP70 1, Heat shock 70 kDa protein 1, Heat shock protein 70 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYI_YERPS
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPDMLKRWYEQDLYGIIRAAKKGKKTFILHDGPPYANGNIHIGHSVNKILKDIIVKSKGMAGYDSPYIPGWDCHGLPIELKVEQLIGKPGEKVSAAEFRTACRKYAAEQVEGQKKDFIRLGVLGDWDHPYLTMDFKTEANIIRALSKIIDNGHLHKGAKPVHWCTDCGSSLAEAEVEYYDKTSQSIDVRFNAVDTATVAAKFGVSAVNGPISLVIWTTTPWTLPANRAISLNAEYLYQLVQVEGECLILAADLVESVMKRAGITQWAVLGSCTGSDLELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDFVIGQKYGLEVANPVGPNGCYLAGTYPTLDGLFVFKANDVVVELLREKGALLHVEKLLHSYPCCWRHKTPIIFRATPQWFISMDQKGLRKQSLQEIKGVQWIPDWGQARIETMVANRPDWCISRQRTWGVPMSLFVHKETEQLHPRSIELMEEVAKRVEQDGIQAWWDLDPAEILGADAADYVKVPDTLDVWFDSGSTHSSVVDVRPEFGGHSPDMYLEGSDQHRGWFMSSLMIATAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTISPQDVMNKLGGDILRLWVASTDYTGEIAVSDEILKRSADSYRRIRNTARFLLANLNGFDPAQHQVKPEEMVVVDRWAVGRAQAAQAEIMEAYENYDFHLVVQRLMQFCSVEMGSFYLDIIKDRQYTAKGDGIARRSCQTALFHIAEALVRWMAPIMSFTADEIWNHLPGERQQYVFTEEWYDGLFGLAGNESMNDTFWAELLKVRGEVNKVLEQARSDKRIGGSLEAAVTLYAEPELAARLNSLQDELRFVLLTSAAKVAAYADAGNDAQQSELIAGLKITFNKADGEKCPRCWHYTQDVGLVAEHAELCGRCVTNVAGDGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_ARCFU
Sequence: MKLENFYVKDDASTDESYGCYPTKRPMEEYIRKGLVCIDKPMGPSSHEVVVWVRRILNVSKTGHAGTLDPRVTGVLPIFIENATKMVKFLQESSKEYVCLMRLHGDAKREDVEKVMKLFVGRIYQRPPLKSAVKKVLRIREIYEMELLEMEGRDVLFRVVTESGTYIRKLCRDIGEVLGTGAHMQELRRTRTGKFGEDMCYTLQDLLDAYVFWKEEGEEKYLREIIKPMEVAAAELPKIVIKDSAVDAICHGANLSVRGVAYVEKNVKKDSTVAIFTLKNELVAIGRALMDAEDIYRLKKGIAADIQRVMMERGVYPKVWKSSSD
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.