PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_ROTPG
Sequence: MGKYNLILSEYLSFVYNSQSAVQIPIYYSSNPELEKRCIDFHAKCVDNSKKGLSLKPLFEEYKDVIDNATLLSILSYSYDKYNAVERKLVNYAKGKPLEADLTANELDYENNKITSELFQSAKEYTYSLMDPAILTSLSSNLNAVMFWLERHSNDVADANKIYKRRLDLFTIVASTINKYGVPRHNEKYRYEYEVMKDKPYYLVTWANSAIEMLMSVFSHEDYLIAKELMVLSCSNRSTLAKLVSSPMSILVALIDINGTFITNEEFDLEFSDKYVRAIVPDQTFDELQEMIDNMKKAGLVDIPRMIQEWLVDCSLEKFTLMSKIYSWSFHVGFRKQKMIDAALDQLKTEYTEDVDNEMYNEYTMLIRDEIVKMLEVPVKHDDHLLRNSELAGLLSMSSASNGASRQLKFGRKTIFSTKKNMHVMDDIARGRYTPGVIPPVNVDRPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLSYAKHTREYAEFYSQSNQLLSYGDVTRFLSSNSMVLYTDVSQWDSSQHNTQPFRKGIIMGLDMLANMTNDPKVVQTLNLYKQTQINLMDSYVQIPDGDVIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRIANKYSFITKIIRVDGDDNYAVLQFNTDVTKQMVQEVSNDVRYIYSRMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQSTQWDQAAILYSNYIVNKLRGFETDREFILTKIIQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADEIASSQTFKNYVSKLSDQLLVSKNAIVSKGIAVTEKAKLNSYAPVYLEKRRAQISALLTMLQKPVSFKSNKITINDILRDIKPFFVTTEASLPIQYRKFMPTLPDNVQYVIQCIGSRTYQIEDSGSKSSISKLISKYSVYKPSIEELYRVISLREQEIQLYLVSLGVPPVDASTYVGSRIYSQDKYKILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEIINYAIKNKSWISLFCNYPKSEMIKLWKKMWNITAFRSPYTSANFFED
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: CHEB1_CUPPJ
Sequence: MKVGIVNDSALAVAALRRAIALDPAFEIVWVAGDGEQAVQLAASHTPDVILMDLLMPVMDGVEATRRIMAATPCPIVVVTTDLGRNATQVFDAMGHGAIDAVDTPTLTESDAKLTAGPLLRKMRNIGRLVAGRAAPRPAITEMPGTLAASRLVAIGASAGGPAALAKLLGALPADFCAAVVAVQHVDEAFAPGMADWLDSQCALPVRVAAPGETPQAGTVLIAGTNNHLRLLGSNRMAYTEQPSEYLYRPSIDVFFESVVEYWRGQAIGVLLTGMGRDGASGLKAMRDHGCLTIAQDQATSAVYGMPKAAAAMGAASEILPLTAIAPRLVQACCSVRPPPG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_NITOC
Sequence: MVEPQVAPIAPMMRRIRRIHFVGIGGVGMGGIAEVLLNLGYQISGSDLRKNQLIQRLLSLGAQIRIGHDPQHVEGCDVVVVSSAIDEDNTEVSAARGRLIPVVPRAEMLAELMRFRYGIAVAGTHGKTTTTSLIAGILGEANLDPTFVIGGQVNSIGANSRLGKGEYLVAEADESDASFLLLQPLLAVITNVDADHMDAYGGDFTALKAAFLEFLHHLPFYGLAVVCLDDPVLRELLPGIGRPVLTYGTCKEADYHLRELKQTQGQTQFQVARPGKDNWLTVVLNLPGAHNALNALAAIAVAHELGIADSAIQRFLKGFSGIGRRFQCYGEIATPAGKVLLVDDYGHHPRELAATLEAIRAGWPERRLVVIFQPHRYTRTRDLFEEFIRVLSQVDVLLLLEVYPAGEAPIGGADSRALWQAIQTHGQVSPILVEDKEIIGEMLFDLLQEGDLLLTVGAGDIGALARRLSISLEGKR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBE_ALOBE
Sequence: MVHFTAEEKAAITSLWGKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TF2B2_THEKO
Sequence: MRGISPKRVCPICGSTEFIYDPRRGEIVCAKCGYVIEENVVDEGPEWRAFEPGQREKRARTGAPMTLMIHDKGLSTDIDWRDKDIHGNQITGMYRNKLRRLRMWQRRMRINDAAERNLAFALSELDRMAAQLRLPRHLKEVAASLYRKAVMKKLIRGRSIEGMVSAALYAACRMEGIPRTLDEIASVSKVSKKEIGRSYRFMARGLGLNLRPTSPIEYVDRFGDALGVSARTKKRAKEILNEAIKRGITSGKGPTGLAAAALYIAALLEGEKKTQREVAEVAHVTEVTVRNRYKELVEKLGINVPI
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 2, TFIIB 2.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: YHAM_HALH5
Sequence: MSRGILYYQVGEALESYFLIKSATKAVASNGKPFLTLILSDHTGEIEAKLWGCSPEDEATFVSGAIVHISGQLSEYRGRQQLKIGSIRPTTAMDQVKVSDFVRSAPLSPDDMLEQITQYIFEMKNPKIQRMTRHLLKKHQTAFLEYPAATTNHHEFVSGLAYHVVCMLNVAKSLAALYPTLDTDLLYAGIILHDLGKVKELSGPIDTTYTIEGKLLGHISILVNEIGETANELGIEGEEVIILQHLVLAHHSKGEWGSPKPPLIREAEILHMIDNIDAKMNMMDRALERVQPGEFSERIKAMDNRSFYKPNFHEPPLDLS
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: Y1344_METBU
Sequence: MLSASEGEQTVRLARNTIESFLKDGEQSDSIDLPEVFGELRGVFVTLTKNGNLRGCIGHPYADSVLESAIVDSAISAATRDPRFPMVDISEMSDIIVEVTVLTQPELVDVLPDKLPEVIEIGRHGLIAKMGMYQGLLLPQVAPENDFDAIDLLNHTCLKAGLPQDAWLTGAQMYWFEGQIFKEVEPRGDIEENKFNSCCK
What are the official names of this protein?
Protein Mbur_1344.
Protein: PXPA_ACIB3
Sequence: MFVDLNSDLGESFGSWKMGNDDQILPVVTSANIACGFHAGDPLGILKTVRKAVELGVTIGAHVSYPDLVGFGRRNMDLSRDELIADVLYQISALDGLAKVAGSKVQYVKPHGALYNTIAYDQVQAAAVIDAIKMYNPELVLVALAGSNLVEQARAAGLKVVSEAFADRAYNSDGSLVSRRLEGAVLHDSAFVASRVVSMLKNGGVESIDGVFTPIQADTICLHGDTDGALEMSAAIKAELVKNNIEIRPFVNKA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RS20_CORU7
Sequence: MANIKQTKKRVLTNEIARQRNKAVRSRLRTESRKFHALVEAGDKDAAEKQMRVAARLYDKAVTKGVLHRNNAANKKSRMAAHLNGMK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SPSAA_XENLA
Sequence: MKVLCEDVNGPRSSLGRAWSHMSWLYYQYLLVTALYMLEPWERTVFNSMLVSIVGMALYTGYIFMPQHILAILHYFEIVQ
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase small subunit A-A, Small subunit of serine palmitoyltransferase A-A, ssSPTa-A.
What is the protein family that this protein belongs to?
Belongs to the SPTSS family. SPTSSA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UBAD2_DANRE
Sequence: MSVNMDELRHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSSFFQEANIPSHHQMMCTPRNTPATPPNFPDAITMFSKLRASECPGGGVSAGGGSSAQVSMACSPPHASFWASPPPNQQPVWLPPSSPTGHHTLHHHHHHMHPPPSWPPVSQPANGPQTPVISALHGQR
What are the official names of this protein?
UBA-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the UBALD family.
Protein: LGT_NOSS1
Sequence: MALPLAFLFTSPGPVLVEIGPITIRWYGLLIATAVLIGVSLSQYLAKRRQVNPDLLSDLSIWLVIGAIPAARIYYVLFQWSEYAQHPERIIAIWQGGIAIHGAIIGGTLAALIFAKLKRVPFWQLADLVAPSLILGQAIGRWGNFFNSEAFGRPTNLPWKLYIPIERRPPDLVSFEYFHPTFLYESIWDLMVFALLITLFFRSLAGKPRLKVGTLFMVYLATYSLGRLWIEGLRTDSLMLGPLRIAQVVSLTGIALGLAGLAWLYVRKRPLPDVVPSAKDTGE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_GRATL
Sequence: MTYTYLHNKFLSIIPKYKNLIKPLSILIALSGGKDSLCLVKLIEDFNNTYNHFSRIEYIYIDHQWRSDSKQNIKHLLNYISITNNNTYIYQINKMEISEANMRNIRYQAIVRHAIQNSHDIIVTGHNQTDQVETFLLNLMRGTGLEGLSSLPYIRKITDQIQVIRPLIHINTGDVLWFCRKFNLPIWSDKTNFYYTNFRNRIRYELLPYLKEYFHPKIESNIINFLSLSSIENEYIKQNSIKLYLASRHSHYIAINYKIIKNQHLALQKRVLNIFFYHNFNKYVNSHILNQLIKMKYQRKLTIVWETLRIKIYKNWIYIQ
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, chloroplastic, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EZH1_HUMAN
Sequence: MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
What is the function of this protein?
Polycomb group (PcG) protein.  Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene.  Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively.  Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity.  Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
What are the official names of this protein?
Histone-lysine N-methyltransferase EZH1, ENX-2, Enhancer of zeste homolog 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with trimethylated 'Lys-27' of histone H3.
Protein: SYR_STAAC
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL124_ORYSJ
Sequence: MAASNFFLLTAFIALVATQAMASDPSPLQDFCVADKHSPVRVNGLPCKDAKDVSVDDFFLAANLDKPMDTTKSKAGSNVTLINVMKLAGLNTLSISMARIDYAPKGQNPPHTHPRATEILTVLEGSLYVGFVTSNQANRENKLFTKTLNKGDVFVFPQGLIHFQFNPSYDKPAVAIAALSSQNPGAITIANAVFGSHPPISDDVLAKAFQVDKKAMDWLQAQFWENNHN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Putative germin-like protein 12-4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CYAA_ECOL6
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRREVLSQLVKEWEWDDARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGVVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQEHDAPLLQQYFS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_LEPBA
Sequence: MVPRLKSKYEKEIRPTLQKSLGFQSVMRVPKLEKIVINVGMGEAHTNPKAMEACLVEIGQITGQRPVKTFAKKSIAGFKVREGMVLGCKVTLRGHHMYEFLDRFINVALPRVRDFRGVNPKGFDGRGNYNLSVREQIIFPEIQFDKINTIYGINITFVTNTEVDKEAFELFQAFGMPYRTAGK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PG24_MYCTU
Sequence: MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTFTAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGGPGGAAGLFGNGGAGGAGGDGPGNGAAGGAGGAGGLLFGSGGAGGPGGVGNTGTGGLGGDGGAAGLFGAGGIGGAGGPGFNGGAGGAGGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGLFSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGTGGTGTGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGLGAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSADQMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGLSGAGGAGGAGGFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGNGGDGGAGGASVVANGGVGGSGGNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSPGLS
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS24.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: NQRF_SHEHA
Sequence: GGSCGQCKVHVKSGGGDILPTELGHISKGEAREGCRLSCQVNVKTNMEIELEDEIFGVKKWECTVISNDNKATFIKELKLQIPDGDSVPFRAGGYIQIEAPAHHVKYADYDIPAEYRGDWDHFGFFKLESKVDEETIRAYSMANYPEEEGIIMLNVRIASPPPRDLSLPCGKMSSYIFSLNAGDKVTISGPFGEFFAKDTDNEMVFVGGGAGMAPMRSHIFDQLKRLHTSRKMSFWYGARSKREMFYVEDFDGLAAENENFDWHVALSDPQPEDNWEGKTGFIHNVLYESYLRDHEAPEDCEY
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: COBQ_MOOTA
Sequence: MAKAIMLQGTSSNVGKSVLAAALCRIFHRNGYRVSPFKSQNMALNSGATPDGGEMGRAQIVQAMAAGVVPRVEMNPILLKPTAHASSQVIVLGRPVGNLGAREYHGHFNQKLWSRVEEAYAFLEREFEIIVIEGAGSPAEINLKAGEIANMRVARMAGAPVLLVADIDRGGALAAVVGTLELLEPEERVMVAGIIINKFRGDLDLLKPALDFLESRTGKPVLGVIPFLPDHGLPEEDSVVLEGVTGRSTGAGEVEIAVIKLPCISNFTDFDALEREKGVNLRYVEAASDLGNPDLVILPGSKNTIGDLLWLRCQGLETAIKELAGRGTPIIGICGGYQMLGKEIRDPEHVETDVEMIKGLDLLPIKTVFQTSKATNQVRGVVTGSGPFLGPLQGQEVQGYEIHMGASFLLDGRPAFKITSRGGRLVTLDDGALAGEGRIWGTYIHGILDNDSLRHQVISVLRARRGLPARPGMLNFMAEQERRLDILAGEVARHLDLGRLAAIMGLERPLVWTGHDN
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: LIN41_CAEEL
Sequence: MATIVPCSLEKEEGAPSGPRRLQTEIDVDANDSGNELSMGGSSSEGDSMSHHRGEHSPNHHHQDNHLGSGPPPPQFTGSLFDTPPSMIQSPQQQPQFQFNTGFGLGLPQDSFRCSVCSKSSTIGVLPFVCAHKTCQSCYQMTPSSYDRRACKLCGAVSTATANFTSQMYLSPTLPSPPRGALMSDCSTPTMNNHINSSTPLHQPRAFSFSLSGMPGSPSPVMGARMPSSAGGLMMRPIGFPDSDSSLTSWSPLQQPSQLSINNLSSIGGHQQQSPMLMQNVFDSLAVNDDTPVFSPLSPTNTSMHMPPSLMASPDVPKHSATIAPPRNSMCSTPRLQLATPMSSQSQQTFPIPSPLGSQPQQQQPMGPIQCQGCESKISFAYCMQCQEALCIHCVQAHQRVRATKQHAFVELQQLMATLMSRAVQPQQAQQYTQNVGGSVRQALGSVGSGDVFFSGHVSGVENDSIGSGESSPRSSSVCGTHDSVIIGICENCPHSVLLCAICVAQHPGKHRVQPLGDIRVAVGEVVNESQLLQWQCEKTGDTIKQIIDGIVTNATTAENEIRAAFDTHVNALEERRKELLKRVETVKNLKLSVLISQAESLQSKQIDLQQAIQTATKLMDSSDCDEMVLRQVFEKLASCQMGNEGTEPNNNILNVLMLACQVNEDDRLKFTAPQDGILLNKARQFGNIESGPCAKNSSIVGDSFKKAIRERQTVIYVQLRDACGDLLSSSIAATQPTSQALLPHQEPHSHLEQAMPTSDVQAFVISPDGSTVEVTMTPRENGIVALSYYPSIEGSYTLNILVKGTPISGCPTTMDIRRGRNYDEIAAKGPILTFGKEGSGDGELCRPWGICVDQRGRVIVADRSNNRVQIFDKDGNFISKFGTSGNRPGQFDRPAGITTNSLNNIVVADKDNHRVQVFDENGMFLLKFGDRGRAVGYFNYPWGVATNSHNAIAVSDTRNHRVQIFTPQGQFVRKCGFDSAYFFKNLDSPRGLCYLPDGQLLITDFNNHRLAVLSPRNMSEMKVYGSEGDGDGMFVRPQGVVIDPEGHILVCDSRNNRVQVFASDDMRFIGSFGLGPVPNSGFQMPQELPAPYSSLGGPFGAPAFSSAPTPLTPSPRQLLDRPTDLAVGPDGRIYVVDFGNNCIRVF
What is the function of this protein?
Heterochronic protein which acts downstream of let-7 in temporal patterning (PubMed:10882102, PubMed:30910805).  Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production (PubMed:28933985).  Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division (PubMed:10882102).  Involved in post-transcriptional gene regulation, uses two independent pathways (PubMed:28157501).  Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repression of translation (PubMed:28111013, PubMed:30910805).  Degrades the mRNA of transcription factor dmd-3 to govern the timing and extent of male tail tip morphogenesis (PubMed:16806150, PubMed:18550714, PubMed:28111013, PubMed:30910805, PubMed:26811380, PubMed:30956008).  Plays a role in the sexual maturation of the nervous system (PubMed:31264582).
What are the official names of this protein?
Protein lin-41, Abnormal cell lineage protein 41.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: CNIH3_HUMAN
Sequence: MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
What are the official names of this protein?
Protein cornichon homolog 3, CNIH-3, Cornichon family AMPA receptor auxiliary protein 3.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Protein: RS5_CAUVN
Sequence: MARGEQQRGEGGQRRDRRDRNAPEERVDSDIVEKLVHINRVAATVKGGRRFSFAALMVVGDQKGRVGFGHGKAREVPEAIRKATEEAKKTMIRVPLRESRTLHHDGAGRWGAGKVMMRAAPPGTGVIAGGPMRAVLETLGVQDVVAKSTGSSNPYNMVRATFEALKVQSSPRQIAAKRGKKVGDILGRRADGASAPEAIEG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y2654_LISW6
Sequence: MRGMGNMQGMMKQMQKMQKEMAKAQADLEVQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDPEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNLPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein lwe2654.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.