PharMolix/UniProtQA huggingface dataset:
Protein: MURQ_FRATH
Sequence: MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSLRNGGRIIYIGAGTSGRLGILDAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDAANFGKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGATTVAISCTKQAKISKYAKYSIEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSKNIICEVTGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: NU1M_PHATE
Sequence: MSIINLLTTIIPVLLAVAFLTLAERKVLGYMQLRKGPNIVGPWGLLQPIADAVKLFTKEPLRPLTSSIMMFIMAPILALALALTMWMPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGANRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLIITQEKLWLLVPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNALSTTLFLGGFHNSYNPSLYTTNFIMKVLILTMAFLWIRASYPRFRYDQLMHLLWKNFLPLTLAMCMWYISMPIAMSSIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
Protein: THIM_GEOSW
Sequence: MNNQEAINALQMVRQANPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVADMAKIAGALVLNIGTLNPTEVEAMIIAGKAANEAGVPVIFDPVGAGATPYRTETARNIASAVQLSVIRGNAAEIANTIGESWTIKGVDAGEGSGDVVSLAKKAAKQLKTVVAITGKEDVVTDGNTTYIIRNGHPLLTKVTGTGCLLTSVIGAFAAVERDVLKAAAAALVIYGVAAEIAAKNAGDEGPGSFQIAFLDALSRVGADEISRYGRIEQGE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: FPG_SALPB
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLKDFLQGDGKPGYFAQELQVYGRKGEPCRVCGTPIAATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RUTE_ECO45
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIFACRALGLDTGPMSGFDRQYVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: HSLU_RICRO
Sequence: MKATKTTYKKDPMGLTPSQIVNELNRFIVGQEKAKKAVAIALRNRCRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLATLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKTLAKTKVDIHAREKAIERILDSLVGKTSSSETREKFKEKILNGELDDTEIEISVADTTPVGGGSFEIPGMPGASMGVLNLGDMIGRALGSSKTKTKKMLVKDAMAIIIPEESEKLIDQEKIIQQAINLAENDGIVFIDEIDKIASTGSSRAKNAEISREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNSLTKDDMIKILLEPETSLIKQYSALIGTEDVRLEFAASAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKGKKITIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSR1_YEAST
Sequence: MAGHSHRSSLKNGHKSYKSKHASKGALKRLYKGKVEKEPVGTGKPDKQVSKLQRKNKAKQLRAQRILDSIENRKLFEGKNGAAKIITIVPLVNDLDPLDILYKLLKCADDEGIMVQEVDSKRIFNVHIKKFKSNLKIIIPDMTNFLNILDCAKVADFVVFGLSGVQEVDEEFGEQIIRALELQGIASYIGVISNLSAVHEKEKFQLDVKQSLESYFKHFFPSEERVYNLEKNSDALNVLRTLCQRLPRSINWRDNRGYVVADFVDFVETSPDSGDLVIEGTVRGIGFNANRLVHIPDFGDFQLNKIEKISESSQKRKIIKEKATDSLSLELDLQTVFESNMNRDTLDEYAPEGTEDWSDYDEDFEYDGLTTARYDDHGFLPGREQTSKKAAVPKGTSDYQAKWYLDDVIDANEEEEAEQTNGKDETMMEIDDEMMVEQDNEEVAGDEEYDIEDNEGFEELSPEEEERQLREFRDMEKEDREFPDEIELEPSESAIERLKRYRGLKNLYNCDWQVDEKDPSSPAEWKRLLRIGNYKNTKNRIIKETKNEAQAIAGDRIRMFIRFPKFLLEKIQDPKQLLFAVYGLLLHEHKNAVVNFSLQRWEQYDKPVPSQEPIVVQYGVRRYTIQPLFSQGSNSPNNVHKYERFLHPDTVSVATCIAPVDFTQSPAIFFKPSPTDAKNIELIGHGTFLNADHSRILAKRAILTGHPFRFHKTVVTVRYMFFRPEDVEWFKSIPLFTKSGRSGFIKESLGTHGYFKATFDGKLSAQDVVAMSLYKRMWPMPSLPWNGM
What is the function of this protein?
Required for 40S ribosomal subunit synthesis.  Required for normal export of the pre-40S particles from the nucleus to the cytoplasm.  Its subcellular location and association with pre-40S subunitshifts from mixed cytoplasm/nucleus to all nuclear in RPS19 disruptions, suggesting it acts after the ribosomal protein.
What are the official names of this protein?
Ribosome biogenesis protein TSR1, 20S rRNA accumulation protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: DTD_CERS4
Sequence: MRALIQRVSEASVTVEGELLGEIGPGLLILVCAMQGDGEAQASALAARIAKLRIFRDEAGKMNRSVRDTGGAALVVSQFTLAADTSRGNRPGFSAAAPPADGERLYRHFAAEIAACGIPTATGRFGADMKVRLLNDGPVTIWMET
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y498_MYCBO
Sequence: MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNAWRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIGVAVVVLVTSPSVPTANVALII
What are the official names of this protein?
Putative amino-acid transporter Mb0498.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CARM1_CULQU
Sequence: MCEQLARLHGCNILIIGDNDCLVNKYGHSVTIACGYDPQGMSVRILKEGGGGGGGGGGGQQLEEYPVNAKTTHLNHGHTSHVVVAGGEMLYLKFASKADCQLFRSLLQKMSGKVNSVFNLRTEDSSASQYFQFYGYLSQQQNMMQDFVRTSTYQRAIYSNSQDFHNKIVLDVGAGSGILSFFAVQAGAAKVYAVEASNMAQYAQQLVHSNNLNGKITVIAGKIEEIELPEMVDVIISEPMGYMLYNERMLETYLHGKKWLKPEGKMFPSRGDLHVAPFTDEALYMEQYNKANFWMQSEFHGVNLVSLRDAAMKEYFRQPIVDTFDIRICMAKSIRHTTNFLTADEKDLHRIQIDVEFHILETGTCHGLAFWFDVEFAGSCSQIWLSTAPTESLTHWYQVRCLLQTPIFVKQGQVLSGKVVLAANQRQSYDVEIDLKLEGTMITSCNTLDLKNPYFRYTGAPVPAPPGSNTTSPSEAYWGQLDAQGARNAVNLVNGITVNGLGEVDMSIINSNMMPMGNQPNIHPGLISSTGRQQSAQQQVTPSQQLTMNPTIACAATSTQNVAQQQLIGGAISPSLFTTPTQQIINSHHAQPIHGGQFY
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling.
What are the official names of this protein?
Histone-arginine methyltransferase CARMER.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BIOF_MYCTA
Sequence: MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGLGVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLNAGELELARRVLTDVLAVARR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PSK1_ORYSJ
Sequence: MVNPGRTARALCLLCLALLLLGQDTHSRKLLLQEKHSHGVGNGTTTTQEPSRENGGSTGSNNNGQLQFDSAKWEEFHTDYIYTQDVKKP
What is the function of this protein?
Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation.
What are the official names of this protein?
Phytosulfokines 1.
What is the protein family that this protein belongs to?
Belongs to the phytosulfokine family.
What are the subcellular locations of this protein?
Secreted.
Protein: SELO_CERS1
Sequence: MTFRFDNSYARDLEGFYVDWPAAPVPAPRLLRLNRPLAEELGLDPDLLEREGAEIFSGRRLPEGAHPLAQAYAGHQFGGFSPQLGDGRALLIGEITDRAGRRRDLQLKGSGRTPFSRGADGKAALGPVLREYLVGEAMHGLGIPTTRALAAVATGEPLLRQEGERPGAILTRVAASHIRVGTFQFFAARSDIERVRRLADYAIARHYPELASAPEPYLAFYEAVAEAQAQLVARWMLVGFIHGVMNTDNMTISGETIDYGPCAFMEGYDPGTVFSSIDLQGRYAYGNQPFILAWNLARLGEALLPLLDADAERAADKANSVLETVGARYQGHWLAGMRAKLGLSGAEEGDARLAEDLLEAMRSQRADWTLTFRRLADAVTDEGALRPLFRDGSALEAWLPRWRDRLAPDAAQRMRATNPIYIARNHRVEEALAAAHAGDLAPFDRLLEALAEPFTERADRELFALPAPEGFDDSYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: GLGB_SHESW
Sequence: MMTQANAYFYNGADVALLNGQYTDVFSLLGMHTSEDGKSLIVRCFLRNALKVDVISIKDGRRVAGLEKVNDAGLFAGTMGRRVKPFLYLLRIQYPLSQIEIVDPYQFGPLLNADDLYLFGEGSAERAYEFLGANWRDVEGIEGVHFCVWAPNAKRVSVVGDFNHWDDTRHVMRQHMANGLWEIFLPNVAEGAHYKFDLVHPNGERHAKSDPMATQMECAPHNASIVPKKSKHSWKDTLWMNKRAVTAWHKAPMAIYEVHLGSWRRKGDNGEQYLDYQDLIEQLIPYVKAQSFTHIELMPISEYPFDGSWGYQPVGLYAPTHRFGDANGLKAFVDACHQADIGVVLDWVAAHFPKDPHGLVRFDGTCLYEHEDPRKGTHPDWDTLIYNYGRGEVRSFLLSNACYWLREFHFDGLRIDAVSSMLYLDYSREPGQWLPNAYGGRENLEAISFLQMLNQRLYQAFPGICMIAEESTAFAGVTKPTDHHGLGFGFKWNMGWMNDSLSYLSRDPIYRQYHHHQLTFSLMYAYTEQFMLSVSHDEVVHGKGSLLHKIPGDDWQKFATLRAYYGFMWGHPGKKLLFMGSEFAQRDEWDHNHSLDWHLLAFEPHQGVQRWLKDLNQLYQGMSALSVLDYQPAGFRWLDCDNGSASIFTFVRYGLAGDAPLVFVINMTPSVHHGFRIGLPQAGDFCEYLNSDSYLYGGSNQGNAGLVVAQNQSWQGMESSALITVPPLSCLVLGPVANQVEAKRR
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RLR61_PLAVT
Sequence: MAFQLRIVQHLLHITFLRLPLAYPSQIHQRENERMFLLRIHRQDVQHLSHRRLRQLNEHRSLLPKGFPFKLLRPLPQLQRLLSQVCRGSVRIDACCCIPSCH
What is the function of this protein?
Effector that partially suppresses the tobacco programmed cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 61.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host chloroplast envelope. Host cytoplasm. Host nucleus.
Protein: PURA_PSECP
Sequence: MPAIVIVGAQWGDEGKGKATDLLGGRVDYVVKPNGGNNAGHTVVVGGEKYELKLLPAGILSPNAVPIIGNGCVVNLEALFQEIDGLQARGADTSKLRVSANAHLVAPYHQVLDKVTERFLGKRAIGTTGRGIGPAYMDKVARLGIRVQDVFDESILRQKVEGSLHQKNEVLVKIYNRRSVVVDEIVEYFLSFAERLRPLVIDSTLVLNTALDEGKVVLMEGGQATFLDVDHGTYPFVTSSNPTAGGASVGSGIGPTRISRSIGIIKAYTTRVGAGPFPTELFDEMGVYLQKTGGEFGVNTGRPRRCGWYDAVLARHASRVNGFTDYFVTKLDVLTGIEQIPVCVAYDVDGVRHDEMPMTQTEFHHAKPIFEYFDGWTEDITGARTLADLPENARNYVLALEKLSGTRFSAIGVGPDRDQTIVVNDLIND
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ATRBE
Sequence: MEEIQRYLQPDSSQQHNFLYPLIFQEYIYALAHDHGLNINRSILLENPGYNNQFSLLIVKRLITRMYQQNHFLISTNDSNKNTFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKILKSHNLRSIHSTFPFLEDNFSHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEYWNLNSLITSKKPGYSFSKKNKRFFFFLYNSYVYECESTFVFLRNQSSHLRPTSFGALLERIYFYGKIERLVEVFAKDLQVTLWLFKDPFMHYVRYQGKSILASKGTFLLINKWKFYLVNFWQCHFSLCFHTGRIHINQLSNHSRDFMGYLSSVRLNPSMVRSQMLENSFIINNAIKKFDTLVPIIPLIGSLAKENFCTVLGHPISKPVWSDLSDSDIIDRFGRICRNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRTFLKRSGSELLEEFLTSEEQVLSLTFPRASSSLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS11_RHILO
Sequence: MAKEAARVRRRERKNISSGVAHVNSTFNNTMITITDAQGNSIAWSSAGAQGFKGSRKSTPFAAQMAAEDVAKKAQEHGMRMLEVEVCGPGSGRESALRALQAAGFTITSIRDVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DEOD_BACC3
Sequence: MSVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGEETTSEERQTTFNEMIEIALDAAIQQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ISCA_SALPK
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTAEDTVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFSNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CYSC_SHEON
Sequence: MSNIVWHQHSVDQAARARLKGQNPVLLWFTGLSGAGKSTLAGALERALFEAGFHTYLLDGDNVRHGLCKDLGFSVADRDENLRRVGEVAKLMVDAGLVVLSAFISPTREERDSIRARFPEGQFIEVHVSTPLSVCELRDPKGLYVKARKGEIAHFTGISSPYEAPLSAELTIDTSKGDLASQVHALIDYLTAIDVISSNRLASLA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: EI2BE_YEAST
Sequence: MAGKKGQKKSGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKASTYPKTRTIEPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLRTDFVKGVISSDILGKHIYAYLTDEYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQDDQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAGSRMYDNESNEQFDQDLDDQTLAVSIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKRRTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVRIATITALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKWVEWLQNADEESSSEEE
What is the function of this protein?
Acts as a catalytic component of the translation initiation factor 2B (eIF2-B or GCD complex), which catalyzes the exchange of eukaryotic initiation factor 2 (eIF-2)-bound GDP for GTP and is regulated by phosphorylated eIF-2.  It activates the synthesis of GCN4 in yeast under amino acid starvation conditions by suppressing the inhibitory effects of multiple AUG codons present in the leader of GCN4 mRNA.  It may promote either repression or activation of GCN4 expression depending on amino acid availability.  GCD6 and GCD7 repress GCN4 expression at the translational level by ensuring that ribosomes which have translated UORF1 will reinitiate at UORF2, -3, or -4 and thus fail to reach the GCN4 start site.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit epsilon, GCD complex subunit GCD6, Guanine nucleotide exchange factor subunit GCD6, eIF-2B GDP-GTP exchange factor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B gamma/epsilon subunits family.
Protein: PIMT_ECOUT
Sequence: MVSRRVQALLDQLRAQGIQDELVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR9_KLULA
Sequence: MSFASTLYKTVFKRNSVFVGTVFASAFVFQAAFDTGVTSWYENHNKGKLWKDIKGGIMNGGEEDEEDDE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 9, Complex III subunit 9.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PYRH_STRGC
Sequence: MVEPKYKRILIKLSGEALAGDKGVGINIQTVQKMAEEIKEVHDLGIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQRVGVDTRVQTAIAMQQVAEPYIRGRALRHLQKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDKTAVKFDELTHRDVISKGLRIMDSTASTLSMDNDIDLVVFNMNEAGNIKRVVFGEQIGTTVSNNL
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEG3_VZVD
Sequence: MSGHTPTYASHRRNRVKLVEAHNRAGLFKERTLDLIRGGASVQDPAFVYAFTAAKEACADLNNQLRSAARIASVEQKIRDIQSKVEEQTSIQQILNTNRRYIAPDFIRGLDKTEDDNTDNIDRLEDAVGPNIEHENHTWFGEDDEALLTQWMLTTHPPTSKYLQLQDLCVPTTIPTDMNQMQPQPISKNENPPTPHTDV
What is the function of this protein?
Contributes to the nuclear transport of the viral transcriptional activator VP16 homolog during the early phase of infection.  Therefore, participates indirectly in the regulation of the immediate-early gene expression.  Additionally, seems to be important for efficient nuclear targeting of capsids (By similarity).
What are the official names of this protein?
Tegument protein UL14 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL14 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.