PharMolix/UniProtQA huggingface dataset:
Protein: MTAB_MALIO
Sequence: MNNDTKINTFAIHTLGCKVNLFESNSIKNDLIMNGLVEVPFDSKADVYIINTCTVTNKADAKSRLYIKRAHVQNKDAIIIVAGCMSQVNKDLMDKLKISIQIGNKYKNSVFDLINEYLKKRERIYRVENILAEKKFEQTTQDFIFLENTRAFIKIQDGCNFMCSYCIIPFSRGRQRSQKMESILEKIKTLVSKXFKEIVLTGVNTAGYLDENNNTFFDLLNNINKLDGDFRVRISSLEPFQINDEIIDLVTSNKKRFCQHWHICLQSGSDDVLKKMNRKYTTDEFYKLMQKILNKSPLTNFTTDYIVGFPTETDEDQKKSIDFLNKIKLYDMHIFPYSKRNNTRSSHYKDINDSTKKDRVKEITKLNYLNKKENLKKYIGKTCEVLFEKKKEDEKMWSGYSNEYCRVMVESGDNLENKMLKVRIKKIFFDSLVGEIID
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MtaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_NEIMB
Sequence: MKYKDLRDFIAMLEQQGKLKRVAHPISPYLEMTEIADRVLRAEGPALLFENPIKPDGTRYGYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEPPKGIKDAFSKLPLLKDIWSMAPNVVKNAPCQEIVWEGEDVDLYQLPIQHCWPEDVAPLVTWGLTVTRGPHKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEFRKLNPDTPYPVAVVLGCDPATILGAVTPVPDTLSEYQFAGLLRGSRTELVKCIGNDLQVPARAEIVLEGVIHPNETALEGPYGDHTGYYNEQDYFPVFTVERITMRENPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMMGCWSFLRQFMYTKFIIVVDDDVNVRDWKEVIWAVTTRMDPVRDTVLVENTPIDYLDFASPVSGLGGKMGLDATNKWPGETDREWGRVIKKDPAVTAKIDGIWEELGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KPTA_TRIV2
Sequence: MEQARQVKISKFLSKHLRHTPERLGLVLAPGGWVAVDELLSACASHQFPISRADLEQVVSNNDKQRFSFDETATKIRANQGHSVEVDLQLQPQLPPPILYHGTGEKSVPAILKSGLLKMSRHHVHLSKDIETARTVGIRHGKPVIFSVDAMVMYQSGFTFYCSDNGVYLVDHVPPEYLHMMN
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: GD1L1_HUMAN
Sequence: MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQKVRLVIAEKGLVCEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEVGSLQHARVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLGGMGYFAYWYLKKKYI
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 1-like 1, GDAP1-L1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: SAT_IGNH4
Sequence: MVSKPHGGKLVERVAKGKTRERLVEEAKEMVNVQVDEGLAADVANVAHGVYSPLEGFMVREDYLSVLEFMRLSNDLPWTIPIILDVDENVKKSVREGDEVAIFFKGKPIAILYVEEIFPWDKNYHTLKVFKTDDLNHPGVRKVFNKKDYLLGGPLIQISDVPEPFEKYRLWPKETRVLFEQKGWKRVAAFQTRNVPHLGHEYVQKAALTFTDGLFVNPLVGWKKPGDFRDEVIIKAYEALIEHYYPKDSVAFSVLRMEMRYAGPREAVHHAIVRKNFGATHFIVGRDHAGVGNYYGPYEAWDIFKNFPDLGITPLFVREAFYCKKCGGMVNEKICPHPEEYRIRISGTKLRKMIMEGKRPPEYMMRPEVAEVVLSFEDPFVH
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: FABV_SHEPW
Sequence: MIIKPRIRGFICTTTHPVGCEANVLEQINITKAKGKIANGPKKVLVVGSSSGYGLSSRITAAFGSDAATLGVFFEKPSSETKPGTAGWYNSAAFDKFAKAEGLYSKSINCDAFSHEAKQKAIELIKEDLGQVDMVVYSLASPVRKLPDSGELIRSSLKPIGEPYKATAVDTNKDIIIEASVEPATEQEINDTVTVMGGEDWELWMQALAEAGVLADGCKTVAYSYIGTELTWPIYWHGALGKAKMDLDRAAHALDDKLSATGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMRAEGLHEGCIEQINRMFSERLYKADGSAAEVDESNRLRLDDWELREEIQQHCRDMWPQVTSENLAELTDYREYKEEFLKLFGFGIEGIDYEQDVNPNVEFDVVSI
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: Y4WH_SINFN
Sequence: MKHIVATLFGILFATAANAAGDSHVLASFPELERALTTGKPVTVTVDLGMCTPATSDTPSTKTRGGVSIDGYRITSDGTLAFADQHFTIDRDGKPVIQFLRYRIRPDGGAEFTMVVFNVPSYERKGTSRVYKCSIGHGLSFFSSQ
What are the official names of this protein?
Uncharacterized protein y4wH.
Protein: HAL4_YEAST
Sequence: MTGMNDNNAAIPQQTPRKHALSSKVMQLFRSGSRSSRQGKASSNIQPPSNINTNVPSASKSAKFGLHTPTTATPRVVSNPSNTAGVSKPGMYMPEYYQSASPSHSSSSASLNNHIDINTSKSSSAASLTSSVSALSLSPTSAINISSKSLSPKFSHHSNSNTAITPAPTPTASNINNVNKITNTSAPICGRFLVHKDGTHEHHLKNAKRQEKLSTMIKNMVGASKLRGEAKSAVPDIIMDPKTTLKSNKNPPTLFAGFMKQVVDMDDKYPEGAPTSGALNCPERDIYRSDQKDSKNNTHNITTTKKDRQCFAEKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEPIESLKRARCRNVIYSMLDPVPYRRINGKQILNSEWGREIKCCHNGRALK
What is the function of this protein?
Promotes K(+) uptake, by the potassium transporter TRK1-TRK2, which leads to the subsequent cellular resistance to toxic cations such as Na(+), Li(+) and Ca(2+).
What are the official names of this protein?
Serine/threonine-protein kinase HAL4/SAT4, Halotolerance protein 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: CP6L1_BLAGE
Sequence: MTLVDWFLDTIALLLGLLHIWIARHFQHWEEKGVHHVAPQPLVGSMLRLLTFSVSPAVFIQGVHEAAGSHPYIGFYIFGRPALLVRDPSLLQHILVKDFSNFTDRLTSSNKHKDPVGAANLFCIKGNRWRQIRACITHTFSTARLKIMFSRVLNSASVTRDYILERGNQPINVKDLFVRTSLDSMCSTLFGIESSTLYNSEAQFLHYGHKMMRWTPYRALEALAHFFSPELLNVFDTRLFECESTEFLINAFSEAITEREKTGLYCSDLVDSLIQLKKQLIDVSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQEVTACHGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRDSIFYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVKLVIIMLLQSLRVETHESTPVPLQLSPYVLFLKNLGRLPLMFVPIGEDNVETSLA
What are the official names of this protein?
Cytochrome P450 6l1, CYPVIL1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: HEM6_SALG2
Sequence: MKPDAHHVKQFLLRLQDDICQKLSAVDGANFVEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVYPRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGNGYTEAYLPIVERRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDWQPEAGSPEAALSEFIQVRDWI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN3_CHICK
Sequence: MPSAINAAVAQQTAAGSVPSTTSTTTEGTGGGTGGIYSAIISRNQPIIKVKEKTYEELHKKCLEENILYEDPDFPPNETSLFYSQKVPIKFEWKRPREICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFHFQFWRYGDWVDVIIDDCLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVIEFYEIKDAPKDIYKIMKHAIARGSLMASSIDDNLGFHYGAAPRSDIGELIARMVKNLENAQMTYSTVDYQGTDERPAWTIMPMQYETRMSCGLVKGHAYSVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSDKSEEWNFIDEEEKIRLQHKIAEDGEFWISLEDFMRHFTKLEICNLTPDTLEADKLQTWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEVPKEMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSKKKKGKPIIFVSDRANSNKELTTDEDAGKDGEKTHVDEKKRSSAKAREKSEEETQFRNIFRQIAGDDMEICREELRNVLNNVVKKHKDLKTEGFELESSRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKHYDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.  Proteolytically cleaves CTBP1.  Mediates, with UTP25, the proteasome-independent degradation of p53/TP53.
What are the official names of this protein?
Calpain-3, Calcium-activated neutral proteinase 3, CANP 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: SYDND_MARMM
Sequence: MHAYRSHTCAELRKAHVGQTARISGWIHRKRDHGGLLFIDLRDHYGLTQVVLEPESPHFATLERLRVESVITVTGEVIARSDETVNANLPTGEIEVRLAELAIQSEAEELPLPVFGEPDWSEEVRLKHRYIDLRRESLHKRIVLRSKIIDSLRRRMVDENFVEYQTPILTASSPEGARDFLVPSRVHPGKFYALPQAPQQFKQLIMVSGFDRYFQIAPCFRDEDARADRAPGEFYQLDMEMSFATQQDVFDVIEPVMKGLFDEFADGRTVPDEPFVQIAYKDAMSWYGSDKPDLRNPIKMSDASETFRGSGFKVFAGMLERNPKVQVWAIPAKTGGSRAFCDRMNSWAQKEGQPGMGYIFWREAEGGLEAAGPIAKNIGEERTEALRVELGLEAGDACFFAAGDPREFAGFAGRARDVVGAELDLCEKDTFRFCWIVDFPMYEWDEDNKKIDFSHNPFSMPQIDPDDFLKLDADTDADTLLALKAYQYDIVCNGVELSSGAVRNHRPDVMLKAFAFAGYDAATVEEEFGGMLNAFRYGAPPHAGVAPGVDRMIMLLAGVENLREVVMFPKDQQARDLMMNAPAEVELKQLRELHIRTVVPDAKKG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLF_SORBI
Sequence: MCLPAKWLHPVSLIFRVAGIGLAAVSAAAMLTASQCTVYADYGWRPRTVTYSDFPAFVYLVAATAIATLLEAVALFLSWSKKGKSKKSWRVLTMLLLGAVVPALLYTSAGAAFAVGWEDIYYYLEPIGRRFSVCRSSVAGGRFCEHVHVSMWLALGAAVAVSFAEFLTTFRWCHGSGSCSDSDSDSDSDSESGCGHGCHCKH
What are the official names of this protein?
CASP-like protein 1U4, SbCASPL1U4.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TXCL2_CALPA
Sequence: MKTQVLAVFVLCVLFCLAESRTTLNKRIDIAKRIECKCKGDAPDLSHMTGTVYFSCKGGDGSWSKCNTYTAVADCCHQA
What is the function of this protein?
In neuromuscular preparation of crustaceans, the toxin increased neurotransmitter release, causing repetitive firing of the axons.  May affect sodium channels (Nav).
What are the official names of this protein?
Delta-hormotoxin-Cpt1a, Delta-HRTX-Cpt1a, Calitoxin-2, CLX-2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RH21_ORYSJ
Sequence: MKRAADGMEKPKFLTREEREKLALERRQAAVTDQRRSALDLLQSLPRPPPPPPPPLSNPPRDSSSSHHRDSSDRDRDRDRDRDRDRDRDRDRERRRDDDSRRDRDRDRDRDRGDSSRRDRDRERGDRDRDRDRERGDRDRERGDREKDRLEKMAEREREKELDAIKEQYLGSKKPKKRVIKPSEKFRFSFDWENTEDTSRDMNSLYQSPHEARLLYGRGFLAGIDRREQKKVAAAHEKETRAEQRRKAGLDDRPEDDAVDKKEADAAAKYDAFDMRVDRHWTQKSLDEMTERDWRIFREDFNISYKGSKVPRPMRKWSESKLGTELLRAVEKAGYKEPSPIQMASIPLGLQQRDVIGIAETGSGKTAAFVLPMLSYITRLPPISEENEAEGPYAVVMAPTRELAQQIEEETVKFATYLGIKVVSIVGGQSIEEQGFKIRQGCEVVIATPGRLLDCLERRYAVLNQCNYVVLDEADRMIDMGFEPQVVGVLDAMPSSNLKPENEDEELDAKTIYRTTYMFSATMPPAVERLARKYLRNPVVVTIGTAGKATDLITQNVIMTKESEKMSRLQKILTDLGDKPAIVFCNTKKSADARAKDLDKAGFRVTTLHGGKSQEQRETSLDGFRNRRFTVLVATDVAGRGIDIPDVAHVINYEMPSSIDTYTHRIGRTGRAGKKGLATSFLTLENTDIFFDLKQMLIQSNSPVPPELARHEASKFKPGSVPDRPPRRNDTVYATH
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 21.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSBM_HELAN
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: XYLA_AGRFC
Sequence: MSTGFFGDIAKIKYEGPDSTNPLAFRHYNPDEIVGGKRMEDHLRFAVAYWHTFTWPGGDPFGGQTFQRPWFEDTMQAAKLKADVAFEFFSLLGSPFYCFHDADVRPEGKNFAENTKNLNEIVDYFAQKQADTGVKLLWGTANLFSNRRFMSGAATNPDPDVFAFSAATVKTCMDATKTLGGANYVLWGGREGYETLLNTDLSRELDQLGRFLNLVVEYKYKIGFEGTILIEPKPQEPTKHQYDYDVATVYAFLQKNGLEKEVKVNIEQGHAILAGHSFEHELAMANAFGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYHVLAGGGFKNGGTNFDSKLRRQSLDPQDLLIGHIGGMDCCARGLKAAAKMIEDGALSKPLSERYAKWDSPEAQKMLRGELKLEEIAALVERDDINPEPKPGRQEYLENVVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I80A4
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECSSPPNNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPYRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGHDKNATASFIYDGRLVDSIGSWSKNILRTQESECVCINGTCTVVMTDGSASERADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPVVDINVKDYSIVSSYVCSGLVGDTPRKNDRSSSSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISEESRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: PGK_UREPA
Sequence: MNSLNKKSIKDLDVNGKTIVLHLDLNVVVDYENKRILNDRKLRASLPTINYLINHNAKIVILSHLGRIKTLADKQSGKYSLEIIVDELRNRVSKNVNRVVFSPLNYGETVVQMVNDLEERDILILENTRYCDISDEGEYVGLEWDGSEILGQFWGMLGDIFIDDAYGVAHRQLSSNYQTAKFAKKSALGFLIVNEINHLDIALEVPKSPYLALIGGNRVADKIAAIEVLCERADQVIIGGGLVYTFLYAQGYNVGLNLVERNMIDDCNNILEKYGKKILICFDFLCNNDFSDTRPIYRKIDEGLEGLYGLDIGKRSLKFIKHEIYRSKTILLNGPFGVIENIKNYAQGTTEICKSMAKQTTRGAYTIICDIDTSSHAEYLGLDKYINFISTGGGASLSYIEEGVLDGLETIDNVPLNVLKKE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CYAP4
Sequence: MARSLKKGPFVADHLLSKVEALNARGERQVIKTWSRASTILPQMIGHTIAVHNGRQHVPVYVTEQMVGHKLGEFAPTRTFRSHTKGDKKARY
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y1004_RALSO
Sequence: MPTLEPSVLDQLFHEARTHNVWLDNPVDDELLHTLYDTVKYGPTAANSTPARFVFVKSAAAKEQLVPCMSAGNQEKTRQAPVTVIVAYDTQFHEQLPKLFPHVDARSWYAGDQARINAAALMNSSLQGGYLVIAARALGLDCGPMGGFDADKVNATFFPDGQWKVNFICNLGYGDTSKVHPRNPRLTFEEACRVL
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase RSc1004.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: RL35_HUMAN
Sequence: MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L35, Large ribosomal subunit protein uL29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_PROM1
Sequence: MEKTREGEIRRETKETDVFVKIDLDGSGKCSANTGIGFLDHMIQQLSSHGLFDIEVRANGDTHIDDHHTNEDVGIAIGQALSKALGDRVGIKRFGHFLAPLDEALIQVVVDCSGRPHLSFSLDIPSQKVGTYDTELVKEFFGAVVSNGGLTLHIRQLAGNNTHHIIEATFKSFARALRMATEIDPRRSSQIPSSKGVLEQAGQ
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_ANOFW
Sequence: MFMSQFHATTIFAIRHQGKGAMAGDGQVTFGNAVVMKHTARKIRKLFHGNVLAGFAGAVADAFTLFEMFEGKLEEYNGNLQRAAVELAKEWRSDKVLRRLEAMLIVMDATHLLLISGTGEVIEPDDGILAIGSGGNYALAAGRALKAYAGEHLTAKQIAQAALKVASDICVYTNDCIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_SHEON
Sequence: MSSKVHLGHTARKRFGQNFLTDDNVINRIVGAIAPDNDHVMVEIGPGLGALTEPVATAIDNLTVVELDRDLVERLQNHPVLKDKLTIHQGDALQFDFSQLVVPGKKLKVFGNLPYNISTPLMFHLFEFAEQIETMHFMLQKEVVLRLSASPGTKAYGRLTVMAQYFCQVVPVLEVPPHSFAPPPKVDSAVVRLLPYAEKPFPCKDVNVLRQLCTTAFNMRRKTLRNNLKQVLSDEEFEQLGIDQNLRPEQISVEQYVAMANMVCDKQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BEII9
Sequence: MARNKIALIGAGQIGGTLAHLAGLKELGDIVLFDIAEGTPQGKALDLAESAPVDGFNAHLSGANDYSAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMESVGAGIKTYAKDAFVICITNPLDAMVWALQKASGLPPQKVVGMAGVLDSARFRYFLSDEFKVSVEDVTAFVLGGHGDDMVPLLRYSTVAGIPLPDLVKIGWTTQEKLDAIVKRTRGGGGEIVNLLKTGSAFYAPAASAIAMAESYLKDKRRVLPVAAQLNGEYGVDKLYVGVPVVIGANGVEKVVEITLDDAEKELFKKSVASVQGLVEACKTINPAFA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: GCH1_STRT1
Sequence: MENQEKVEQAVYQLLEALGENPEREGLLDTPKRVAKMYAEMFSGLNEDPKDQFTAVFSEVHDEVVLVKDIPFYSMCEHHLVPFYGMAHVAYLPSGDKVTGLSKLARAVEVAARRPQLQERLTDQVATALEEALNPRGVFVMVEAEHMCMTMRGIKKPGSKTITTVAKGIYKEDREERKEILSLMRDF
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: NU4LC_WHEAT
Sequence: MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AIM39_YEAST
Sequence: MWGLCKKHFPSNKIQVQERNKALKPKKSGSEHKTKQLFPVFNCKKKEKGVMIRFAILRNANTSLLSARSICLFTQAPTYCHVRLNTLNKSITTKRNSLTESKRHVHDGKHFFTTPHQQQQTKLGEIEEGHSPNIKGEDLRSIGQAITHQRNKRRKQIWSAIFGGIFGVILGYSLIYRVIYLKEQSFLPLFPSSKIRKLSTRDLKKVDVNQVQKLSKLRVLEILSGHDMIKEQYGVPLLDKDGNSPTLNEFSMWCEDQDPCVTGIVMEPDDKRDSSHTWYRIPFVCKWRITHRPISIRGTIDDLLNRIGLETADLFEIISPERVYGSFKYEYPLQGDSHALHLWFHGEIELDDDSLIVYNGKYHVDVKLQEIDLFRREKNGQLIQYVLYKNEAGDK
What are the official names of this protein?
Altered inheritance of mitochondria protein 39, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM39 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.