PharMolix/UniProtQA huggingface dataset:
Protein: SYK_STRP2
Sequence: MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQELKDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETIYRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVDFWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVSPLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATGIDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_ECO57
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHKLSSVFFYREGVYNANHLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGVVDEMEAGRLGLASSNLQQGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3840_PHOLL
Sequence: MFGKGGLGNLMKQAQQMQDKMQKMQEEIASLEVTGESGAGLVKVTINGAHNCRRVEIDPSLMEDDKEMLEDLIAAAFNDAARRIEETQKEKMAGISSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein plu3840.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KHSE_CAMJD
Sequence: MKILVPATSANLGPGFDCLGLSLKLFNETQIQKSGVFSISIGGEGSDNIFLKKNNIFVNIFYEIYEKLSGKKDNFRFIFQNNIPLSRGLGSSSAVIVGAIASAYYMSGFKVEKKRILDEALIYENHPDNIAPATLGGFVCSLVEKNKVYSIKKEIDKDLAAVVVIPNLAMSTEQSRQALAKNLSFNDAVFNLSHASFLTACFLEKKYEFLKFASQDKLHEINRMKNLPELFEVQKFALENKALMSTLSGSGSSFFSLAFKDDALALAKKMQTKFKDFSVQYLEFDDNGFEIC
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_VIBPA
Sequence: MSPIMDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSPGGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAAGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIKQKLNNLLAEHTGQPLEVIERDTDRDNFMSAEQAVEYGIVDAVLSHRGA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_ROSDO
Sequence: MPTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQVTRAQGAMDTVITNALIVDHTGIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEAIAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGGTGPAHGTLATTCTPGSWHIGRMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADDMDVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSSTNPTRPFTVNTLEEHLDMLMVCHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNMRVRRYIAKYTINPAIAHGIAHEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFGAFGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNPETYEVRADGELLTCQPAEVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_SYNS3
Sequence: MRTGEIHRVTGETDVSVRLGLDGSGRCQASTGVPFLDHMLHQISSHGLIDLEITASGDTHIDDHHTNEDVGIAFGQALSKALGDRRGIYRFGHFVAPLDEALVQVVLDCSGRPHISWGLTIPTQKIGTYDTELVKEFFVAVVNNSGLTLHIRQLDGVNSHHIVEACFKAFSRALRMATEIDPRRSGLVPSSKGVLEQAGGS
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVP18_PHANO
Sequence: MTLAEEFKSRNFSIYGQWTGVLCIFLCFALGVANIFHPTFVIAFSIVCLVSSFVIIFIEIPLLLRICPTSPKFDAFIRKFSSNYMRAAIYGVMSVVQWISIWPQATSLIVAAIFLMVAAIFYALAGFKGQQFQGSKTLGGQGVAQMII
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RL4_SHIDS
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DAPF_MYCA1
Sequence: MKFAKGHGTENDFVLLCDTPAELRLTAAGVAALCDRRRGLGADGVLRVTTAGAAAAAGVLDRLPDGVAGDDWYMDYRNSDGSVAQMCGNGVRVFAHYLRASGLETRDEFVVGSLAGPRPVTVHAADATGADVSVDMGKANTLGSGGKAFEATVGGRRFAGLAVDVGNPHLACLDPELSVDELAALDVAAPVSFDAAQFPDGVNVEVLTAPAAGVVHMRVHERGVGETRSCGTGTVAAAVAALTAAGADTGTLTVRVPGGDVVVTVTDATSYLRGPSVLVAHGEISEEWWQQAQR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_SULAC
Sequence: MIKLTDEGEKMLRECAESLVDLFAKNRIVKIKAKVTSGLGEGRIFVSLPYYMEAFNKFLGFQPYPGTLNAVIYDRISMENRLLLDLSRGILIPEHKEPNRVLGSVKAFPASINSVSPVAVVIPTRTTHPKSVVELLSPHKLREKLELEDGDEIEIEVYL
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: RL6_BACSU
Sequence: MSRVGKKLLEIPSDVTVTLNDNNTVAVKGPKGELTRTFHPDMEIKVEDNVLTVARPSDQKEHRALHGTTRSLLGNMVEGVSKGFERGLELVGVGYRASKSGNKLVLNVGYSHPVEIVPEEGIEIEVPSQTKVVVKGTDKERVGAIAANIRAVRSPEPYKGKGIRYEGEVVRRKEGKSAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6, BL10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YMF19_WHEAT
Sequence: MPQLDKLTYFSQFFWLCLLFFTFYILLFNNNNGILGISRILKLRNQLLSHRGGEIRSKDPKNLEDILRKGFSTGLSYMYSSLSEVSQWCKTVDYLGKRRKITLISDFGEISGSRGMERQILYLISKSSYNTSSSRITCWKNIMLTHVLHGQGSIIS
What is the function of this protein?
This is one of the chains of the nonenzymatic component (CF(0) subunit) of the mitochondrial ATPase complex.
What are the official names of this protein?
Putative ATP synthase protein YMF19, 18 kDa membrane-bound protein, Mitochondrial protein YMF19, ORF156.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein YMF19 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ATPA_MYCGA
Sequence: MAINLNEYSLLIKDQIKKYANKIISDQKGYIITIGDGIVRVSGLDDVLLNELVEFENGAYGIALNLEPNSVGVVMLSDYYDLKEGSSVKRTGKVIQAPVGDGLLGRVIDPIGLPIDGKGELKNISGYAPIERLAYGVMQRKSVHQPLETGILAIDSMLPIGKGQRELIIGDRQTGKTTIALDTIINQKGKNVNCIYVAIGQKNSSVAQITRLLEETGAMAYTTIVSATASELAALSYIAPFAGVTIGEEWMRQGKDVLIVYDDLSKHAVAYRALSLLLRRPPGREAYPGDIFYLHSRLLERAGKLSDELGAGSITALPIIETQAGDISAYIPTNVISITDGQLFTTTSLFNSGQRPAIHVGLSVSRVGSAAQLKSIKQVSGSLKLELAQYRELDTFSQFSSDLDAETKIVLEHGARVMEMFKQPQAKPIDQTSEAVLLFGIKNRFIKWIPTDHIIKFKEFILDKIKQDQVYKKIEEKKAFDDEIEKELTAFFKDVVKKYTSTLVDYNGSLYGDLKELE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DSBB_XANCP
Sequence: MNPFRWGFRAQFLLGFLACAGLLAYAIYVQLHLGLEPCPLCIFQRIAFATLALLFLLGALHGPRGAGGRKAYGVLAFIAAGVGMGIAARHVWVQIRPKDMMSSCGPPLSFLSETMGPFEVFRTVLTGTGDCGNIDWRFLGLSMPMWSMVWFVGLALWALYAGFKHRGPRKLF
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCRD_DECAR
Sequence: MNTLNDEAVVERIDKSLARSRVYSLLAIGLGFPDVESHAGFSDGRLMIEMHQALEVCMPGLAEYFSEQIAPRLKLTCSFEDFEALFLTAFETNMPVPSAALYEGVHVQQSNRPGLILELKGFYRNFGLTMDAQGNELEDTLTAELEFMHFLTAKQAQAEMESLSPNAYQRAQRDFLERHLVVWLPLVRAEVNAKVATQFFVALIDLAERFVDAHLEEMLFELNS
What is the function of this protein?
May function as a system-specific molybdenum chaperone protein essential for the assembly of the perchlorate reductase PcrAB complex prior to its periplasmic translocation via the Tat pathway.
What are the official names of this protein?
Perchlorate reductase assembly chaperone protein.
What is the protein family that this protein belongs to?
Belongs to the type II DMSO reductase enzyme chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_MARN8
Sequence: MHCPFCGEADTKVIDSRLVAEGDQVRRRRECLSCRERFTTFETAELVMPRVVKQDGTRQPFDEEKLRAGIMKALEKRPVSIEEIDAALNRIKYRLRSTGEREVKSMQLGEEVMTELRQLDKVAYVRFASVYRSFQDINEFKEEIERLSQGNGDTAVDVARALVDNGTDKGKA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PLP2_MOUSE
Sequence: MADSERLSAPGCWLACTSFSRTKKGILLFAEIILCLVILICFSASTTSAYSSLSVIEMICAAVLLVFYTCDLHSKISFINWPWTDFFRSLIATILYLITSIVVLVEGRGSSRVVAGILGLLATLLFGYDAYITFPLKQQRHTAAPTDPTDGP
What is the function of this protein?
May play a role in cell differentiation in the intestinal epithelium.
What are the official names of this protein?
Proteolipid protein 2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GSA_MYCUA
Sequence: MGSTDQAVTSVRRSAQLFTDACAVIPGGVNSPVRAFTAVGGTPRFITEAHGCWLTDADGNRYADLVCSWGPMILGHAHPAVVEAVSRAAANGLSFGAPTPTETELAAEMIGRVAPVERLRLVNSGTEATMSAVRLARGFTGRSKIIKFSGCYHGHVDALLADAGSGVATLGLPSSPGVTGAAAADTIVLPYNDLEAVRQTFAQHGEQIAAVITEASPGNMGVVPPGRGYNAALRAVTAEHGALLIVDEVMTGFRVSRSGWYGIDPVDADLFTFGKVMSGGLPAAAFGGRAEVMERLAPLGPVYQAGTLSGNPVAMAAGLATLRTADDGVYAALDANADRLARLLAGALTDAGVAHQIPRAGNMLSVFFSETPVTDFAAARNSQTWRFAPFFHALLDAGVYPPCSAFEAWFVSAALDDTAFERIADALPTAARAAANATPESRP
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SYNSC
Sequence: MAERTFIAIKPDGVQRGLVGEILGRFERKGFKLVGLKQITPSRALAEQHYGVHKERPFFAGLVDFITSGPVVAMVWEGDGVIASARKLIGATKPLEAEPGTIRGDLAVNIGRNVIHGSDAAETAQFEIGLWFQASELNDWSPSDQGWRVEG
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_STRP8
Sequence: MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL17_DROME
Sequence: MGRYSRESDNVAKSCKARGPNLRVHFKNTHETAQAIKRMPLRRAQRYLKAVIDQKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAEANADCKGLDADRLVVHHIQVNRAQCLRRRTYRAHGRINPYMSSPCHVEVILTEKEELVSKATDDEPAKKKLSKKKLQRQKEKMLRSE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ATP6_NOVAD
Sequence: MAEGKVDPVHQFTIETLFGTDHWSIGGYNIAFTNSALWMAITTAVLIVFVAGGAKRELVPGRWQMAVEGLTGFVDNLLQANIGKAGRKYLPYVFSLFAFILFANMLGLLPLALVGVHPFTATSHFTVTGVLAIMSFAIVLGVGFAKHGLHFFSLFVPHGTPVPMIPIIFPIELISFMVRPFSLGLRLFVAMMAGHVLLEVLSGFVISGTNAGVGTFFLAAVPSFLLMIGICALELLVAGIQAYVFALLTCVYLNDAENLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEMH_COXB1
Sequence: MAKQAIKRAKILAVKNNNKIGVLLINLGTPDEPSVPAVRRYLRQFLSDPKVIDVPSLVRWIIVHLCILPFRPKRSAKLYQKIWMPEGSPLLVYSEMLRERVGETLGDDFCVALGMRYGKPSIETALKKLQEAQCRQLIVLPLFPQYSTSTTASALEEVRAKNSFKEMTVIDRFFEEPHYIDSMTTLIHENLNEFQPDYFLFSYHGLPERHLVKSGCQLAICNRKNNCSPISSSNENCYRAQCFETSRLIAKKLNLTDQQYGVAFQSRLGRAKWIEPYTDKYLIELSKKGIKKLMVVCPSFPVDCLETLEEIGIRAQSQWQRLGGETLKLIPSLNAHPQWVNAIAKMAKKSLQLF
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_DESDA
Sequence: MSLIPMVIETTGRSERAYDIYSRLLKDRIVLLGSEVNDTVASLICAQLLFLESQDPEKEISLYINSPGGSVTAGLAIYDTLRFISAPVSTVCMGRAASMGAFLLAAGKPGLRYALPNSQIMIHQPSAGYQGQATDIEIHAKEVLRLKERLNRILAENTGRPYKDIVKATERDNFLTPEEAKDLGIIDRVLVSRQDMAQEKSE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP15_CHICK
Sequence: MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI
What is the function of this protein?
Ribosome biogenesis factor.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 15 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DNAA_BARQU
Sequence: MTNIGGPVVENASIEHPVISEEEGAAAFARVMAQLKAQVGIEAYTSWFGRLKLAEYSRNLVKLSVPTAFLRSWINNHYGSLLTNLWKQENSAILRVEVIVRGMKRVSKGVVCRTSAAPVVLEGQTASSFVESYTEPSVKDIEAGVFGSPLDSRYTFESFVEGSSNRVALAAARSIAEGHKSALRFNPLFIHASVGLGKTHLLQAVAAAALKRLMPARVIYLTAEYFMWRFATAIRDNAALSFKEQLRDIDLLIIDDMQFLQGKSIQNEFCHLLNMLLDSAKQVVVAADRPPAELESLDLRVRSRLQGGVALEIEVPDYEMRLKMLRQRLKVVQQDDNMVVISDEVLQYIAKTVLGSGRDIEGAFNQLLFRQSFESDLSLERIDELLGHLTRSGESKRIRIEEIQRAVARHYNVSKQDLLSNRRTRTVVKPRQVAMYLAKMLTPRSLPEIGRRFGGRDHTTVLHAVRKIEDLVCDDQTLAKELELLKRLIGEQAA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPS3_SERL9
Sequence: MAPAPTSVPLVSQPNVISDLKTALAVQGSASDHPRTLHQLLSQAAERYPLQQLGFISSSAHDSSIQTKSYSTFNQHVRNLARALTDWKKPVGSIVVVYLTEHEDNMAAVWACLLAGYIPCLQPALSAQQSHKEGHINHIKNLFLSATWLTNEIGAEQVMSVDGIDIHLFSDLKLAAEGYNVPADWAAVEAKPDDEAILFLTSGSTGFSKAVVHTHRTIIASCYAKGQSYGLTSETNVLNWVGFDHVAGSLEMHITPLLFGSYQLHVHASTILSDPLSFLRLIDDKSINIAFAPNFLLAKLARDLEKRSELYGAFDLSSVKRINSGGEAVVSKTAKIFVTVLKALAKDPSKVSFVVSAGFGMTETCAGCIYDPIDLSVINPMHEFLDLGRPIQGCEMRIVDPEDGITLRPDGESGELQVRGPMVFARYYNNPQATSSSFVEGRWYRTGDIGIIEKGVMRLSGRIKDTVIVHGVSYGIPELETYLQLVEGVTHSFLAAAPYRAPGQETEGFVVFYSPTFDLNEEDASNKLAATHRALRDISVKMITLPPQQIIPIPIDQMEKTTLGKLSRARLLTLFKQGELAKHIARADELLSEARGATFVVPATITETAFAKIFAGVFNLSTDDISAADNFFELGGTSIDVIRLKREGETVFGLPEIPIIQILKHPVLRDLAKYIDALVSKDNTQQEYDPIVPLQLTGNKTPIFFVHPGVGEVLIFVNLAKYFQNERPFYAFRARGFEPGQPFFSKMDEMVSSYAAAMKRTQPKGPYAIAGYSYGGVIAFEVAKRLEAGGDEVKFVGLINIPPHIADRMHEIDWTGGMLNLSYFLGLVSKQDADDLAPTLRPLTRKEQLDVVWKLSPPERLVELQLTPEKLDHWVDIAGSLIECGKDYNPSGSVAVADVFYAIPLRGSKSDWLNNQLKPWSGFSRTEPAFTDVPGRHYTLMDFDHVPQFQKIFRSRLEARGV
What is the function of this protein?
An L-tyrosine:2-oxoglutarate aminotransferase (probably amt1) and atromentin synthetase nps3 catalyze consecutive steps to turn over L-tyrosine into atromentin, which represents the generic precursor molecule for the entire terphenylquinone and pulvinic acid family of pigments, which are widely distributed secondary metabolites in homobasidiomycetes.  The first step catalyzed by the aminotransferase converts L-tyrosine in to 4-hydroxyphenylpyruvate (4-HPP).  Adenylation of two 4-HPP monomers by the nps3 adenylation (A) domain, covalent tethering of the monomers as a thioester and oxoester onto the nps3 thiolation (T) and thioesterase (TE) domains, respectively, and symmetric C-C-bond formation between two monomers catalyzed by the nps3 TE domain leads to atromentin.  Follow-up products of atromentin in S. lacrymans include atromentic acid, xerocomic acid, isoxerocomic acid and variegatic acid.
What are the official names of this protein?
Atromentin synthetase nps3, Nonribosomal peptide synthase-like enzyme 3, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: VPK2_MONPV
Sequence: MGVANDSSPEYQWMSPHRLSDTVILGDCLYFNNIMSQLDLHQNWAPSVRLLNYFKNFNKETLLKIEENDYINSSFFQQKDKRFYPINDDFYHISTGGYGIVFKIDNYVVKFVFEATKLYSPMETTAEFTVPKFLYNNLKGDEKKLIVCAWAMGLNYKLTFLHTLYKRVLHMLLLLIQTMDGQELSLRYSSKVFLKAFNERKDSIKFVKLLSHFYPAVINSNINVINYFNRMFHFFEHEKRTNYEYERGNIIIFPLALYSADKVDTELAIKLGFKSLVQYIKFIFLQMSLLYIKIYELPCCDNFLHADLKPDNILLFDSNEPIIIHLKNKKFVFNERIKSALNDFDFSQVAGIINKKIKNNFKVEHNWYYDFHFFVHTLLKTYPEIEKDIEFSTALEEFIMCTKTDCDKYRLKVSILHPISFLEKFIMRDIFSDWINGRN
What is the function of this protein?
Essential serine-protein kinase involved in the early stage of virion morphogenesis.
What are the official names of this protein?
Serine/threonine-protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: TLK2_XENTR
Sequence: MMEELHSLDPRRQELLEARFTGVGVAKAPLNSESSNQSLCSLGSLSDKELEQTPEKKQNDQRNRKRKADPYETSQGKNTPRGHKISDYFEFACGSGPGTSPGRSVPPVARSSPQHSLSNPLPLPSQQCSPPSTAPVNPEHSCASFKHISVQHRCTQSDLTMDKISALENSKSSDLEKKEGRIDDLLRVNCDLRRQMDEQKKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINTQREEIERQRKMLAKRKPPAMGQTPPANNEQKQRKNKTNGAENEALTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMTEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSIPANAAVASTSGSSNNSLSN
What is the function of this protein?
Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation (By similarity).  Negative regulator of amino acid starvation-induced autophagy (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase tousled-like 2, Tousled-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IHFB_HISS2
Sequence: MTKSELIENLASTNPNVPLKDIENAVKDILEQLSQALENGERIEIRGFGSFSLHFRQSRIGRNPKTGEKVDLSAKYVPHFKAGKELKERVNIYS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.