PharMolix/UniProtQA huggingface dataset:
Protein: RL15_PSEA6
Sequence: MHLNTLAPAPGAKKSSKRVGRGMGSGLGKTGGRGHKGQKSRSGGSVKPGFEGGQMPIQRRLPKFGFTSRKSLVSDQVTLSEIAKVEGEVVSLETLKAAGLVKKEMLFVKVLKSGEISRAVTINGLKVTKGAREAIEAAGGKVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y9256_DICDI
Sequence: MNRLTFYGLCLSGAVGMGLLVGSPICRPVFGELLGANRDQEKREKEIKILMAGGTIDPHHNHHDDHHDSHGHGHGKIKGHH
What are the official names of this protein?
Uncharacterized protein DDB_G0277453.
What are the subcellular locations of this protein?
Secreted.
Protein: TDA2_YEASO
Sequence: MQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNSNECYLITILWLHK
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: RL11_BARQU
Sequence: MAKKSIGQLKLQVPAGAATPSPPIGPALGQRGINIMEFCKAFNAATQEMEKGAPIPVIITYYQDKSFTFSLKTPPVSFFLKKEVNLKSGSKEPGKVSVGRISRDKIRSIAEAKMKDLNANDIEAAMRMVEGSARSMGLEVVG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL30_XYLFA
Sequence: MVHEYDNTLKVCLVRSLIGVPSRHRLSVRALGLRKVSDMRKVNDTPQVRGLIKKVHYLVRIQD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RS13_AYWBP
Sequence: MARIAGIDIPSDKRVVIALTYIYGLGNKLSHKILNELKIDQNIRVKNLTEQQLSALRIEITKYNVEGDLRREVTLNIKRLMEIGAYRGLRHRKGLPVRGQKTRNNAHTVKGKPKAAIAGKKKNKVN
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ISPG_XANAC
Sequence: MHDAVTRPTPPADATAWPRRITRAVKIGSVTVGGGHPVVVQSMTNTDTADIAGSVKQVADLWRAGSEMVRLTVNNAESAAAIPRIVDKLRMMGIEVPLIGDFHYNGHQLLAAEPACAEALAKYRINPGNVGFGKKKDLQFGQLIEFAIKYGKPVRIGANWGSLDQSLAAQLMDENSQRDTPWDAGRVLREALIRSAVDSAERAVELGLPRERIILSAKVSGVQELIAVYRDMASRCDFALHLGLTEAGIGSKGIVASAAALSVLLQEGIGDTIRISLTPEPGQSRTQEVVVAQELLQTTGQRAFTPMVTACPGCGRTTSEFFQELAGVVQNHVRAKMPEWKITNPGAENMTLAVMGCVVNGPGESRHANIGISLPGTGEAPSAPVFIDGEKSVTLRGENIAYEFIELIDQYVERTYVRRAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GLYA_SYMTH
Sequence: MDALKRYDPEVFAAIQQEVERQQRNIELIASENFVPKAVLEAAGTVLTNKYAEGYPGRRYYGGCEYVDIVENIARERLKAAFGAEHVNVQPHSGANANTAVYFAFLQPGDTVLGMNLAQGGHLTHGSPVNFSGRTYNFVPYGLDPETERINMDQVAELARQHRPKLIVAGYSAYPRVLDFKRFREIAEEVGAILMVDMAHFAGLAATGYYPNPVEHAHVVTTTTHKTLRGPRGGAILCKKEFAKEIDKAVFPGMQGGPLMHIIAAKAVAFKQLSDPDYRAYCGQVVKNAKALAQALLERGYRLVTGGTDNHLMLVDLRPKGITGRDAEHLLDRVSITVNKNAIPNDPEKPMVTSGIRIGTPAMTTRGMKEAEMVQIADLIDRAITHRNDEAELDRIRAEVHELTARFPLYAD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_RHILO
Sequence: MHDPHGHAHTVRPPGRGRNWPGPWRKTPGRLLGTSFVRLYQLTLSGFVGNSCRHLPTCSEYAHEAIARHGLWAGGWMGFFRVLRCGPFGTHGIDLVPEVLADRYVWFMPWRYWRIGRKRAETRA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS12_CAMJJ
Sequence: MPTINQLVRKERKKVLEKSKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRPKAGAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MYBK_DICDI
Sequence: MQSDTLTVQTVPNTTNVTNTEHSMLAKIEENRHIIQTIWEKQNLGKLTECEQFQKRLHSNLLLLAPLADHQQNYHKQQQALLQQQQQQQQALLQQQQQSPVTNVATNTPPTLQHSISSPSPNNFNNNNNANNQFLSPNSPQVAKSSPSQNNPSTPIANTPTTTTTTAATTATNTNTMMSGSSGGVVSPVSNQQQQQSIQSPSQQSVVQRSPSQSLNSSASSIQSLQNIQNTQNTIQQLTNSLTQVKTIIQQYQSQNQQVPQDVISRYHEFYSMLQQQQQNLLQQQSLLQQQQALLQQQQVGNPMQQSNDMQPQTPQQNNMQQQQQPQTPQQTNMQQPQTPQQNSMQPSQQPITQQEYQQIYDKIVSMSSQILLCNQNIQKLQSESYDPHVLQGLQNQVANLEIAQANSLRFLPQQYHVVLFQQQQQQQANQQQLQLMQIKQSKEYMVLTPAQQLIYNQQIQQNHYNQQVILRQQQQKLMAILEQQNQMIAQQQQQQHQMHQQHQMQPQQQQQQHQMHQQSPQQPQQMGMGGNPPSLEMISPMSAVMNGVTSPMNQGMMSSNNGMPTITTSLSAISPTSPIGTNLNMSNPTTTTVANVTTTAATTTTASSSGKEEKEKKKDKKDKDKDKDKDDDDKESKKDKKDKKDKKASKEKTSHWTSEEHNKFLEAVQQFGIKDYHAIAKFVQTRNHHQVRTHVNTYLKNQKKAEAATSSTQVSTPQQQLPIVGTPQQSVGTPQQQQPPIEQTPPPPQQQQQPPQLTPEQQLASQQQQATLQFQQYQQPQDQQQQQYQQYQQYDPQQQQQQPQQQPPPPQTTPPNNENNNNINNNLENTNNNDNGNNNNNEYNSGFDSNSGLNDEMGIGLFGSPGNNSNNNLGISIEGNNFDDNPSISSPGV
What are the official names of this protein?
Myb-like protein K.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSSA_PENRW
Sequence: MAPSQLPPVFNPTAQDIEMLLAAQCHLGSKNLQVHMEPYLWKLRADGVNVLNIGKTWEKIVLAARIIAAIDNPADVCVISARPYGQRAVLKFASHTGATAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDAQAIKEASYVNIPVIALCDTDSPTDFVDVAIPTNNKGRHAIGLVWWMLAREVLRLRGTLATRETEWDTVVDLYFYRDPEAEENKEIADESKVAGAEEIGAGAVESGFAGENWDASAPGAGNPGTAFAAASAATGAAAATSWDAEGADWAASSAAPTTEWAEAQPAAGEAKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_ACIB3
Sequence: MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: AROA_SHEDO
Sequence: MKQLHLEPIACIDGEINIPGSKSISNRALLLATLAKGTTTLTNLLDSDDIRYMLASLEQLGVQFELSDDKTRCTVQGMGGAVSASTAQTLFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRQLGASVTYLKNDGFPPLTINATGLNGGDVDIAGDLSSQFLTALLMVAPLAKGKVNINIKGELVSKPYIDITLALMAQFGVDVQNHDYARFEINPGQQYLSPGKVLVEGDASSASYFLAAGAIAGGSVKVTGVGRLSIQGDVKFADALEKMGADIEWGDDFIIARSAKLSGIDMDMNHIPDAAMTIATAALFAEGETCLRNIYNWRIKETDRLHAMATELRKVGAVVEEGHDFIRITPPVKMNTAAIDTYNDHRMAMCFSLLAFADCGITINDPDCTSKTFPSYFAEFARLTQEA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C34_ARATH
Sequence: MGHFSSMFNGIARSFSIKKAKNINSSKSYAKEATDEMAREAKKKELILRSSGCINADGSNNLASVFSRRGEKGVNQDCAIVWEGYGCQEDMIFCGIFDGHGPWGHFVSKQVRNSMPISLLCNWKETLSQTTIAEPDKELQRFAIWKYSFLKTCEAVDLELEHHRKIDSFNSGTTALTIVRQGDVIYIANVGDSRAVLATVSDEGSLVAVQLTVDFKPNLPQEEERIIGCNGRVFCLQDEPGVHRVWQPVDESPGLAMSRAFGDYCIKDYGLVSVPEVTQRHISIRDQFIILATDGVWDVISNQEAIDIVSSTAERAKAAKRLVQQAVRAWNRKRRGIAMDDISAVCLFFHSSSSSPSL
What are the official names of this protein?
Probable protein phosphatase 2C 34, AtPP2C34.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: KDSB2_BURL3
Sequence: MTSFNSGRPVHVVIPARYGSTRLPGKPLVDLAGEPMIARVHARVSRALPGADIVVAIDDARIAAALDARGIRFAMTGAHHASGTDRAAELARVSGWHDTDVVLNVQGDEPLVPEALLKAFADFCVAAPDLGIATVACPVGDAALLDEPGIVKLVVDRRGRALYFSRAAIPFCRDGRSAGADLGGHLRHIGLYGYSNAALQALAHTAPCELEQLEQLEQLRALWLGMPIDVMRWPDAPPAGVDTPDDVARVVSLLKRQTQDETEPY
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase 2, CMP-2-keto-3-deoxyoctulosonic acid synthase 2, CKS 2, CMP-KDO synthase 2.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_PSEPG
Sequence: MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVFGGVVPELASRDHVKRMLPLIRQVLDEAGCVATEIDAIAYTAGPGLVGALLVGASCAQALAFAWDIPAIGVHHMEGHLLAPMLEENPPEFPFVALLVSGGHTQLVRVDGIGQYELLGESLDDAAGEAFDKTAKLIGLNYPGGPEIARLAEQGVPGRFVFPRPMTDRPGLEFSFSGLKTFALNTWQQCKNAGDDGEQTRCDVSLAFQQAVVETLTIKCKRALKQTGLKRLVIAGGVSANKALRASLEEMLAGMKGNVYYARPQFCTDNGAMIAYAGCQRLLAGQQQDLAISVQARWPMEQLPPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_GEODF
Sequence: MERWNINDSSKIYNLDNWGADLFSINKKGNVCVHPSPSSKSSIDLRVLVDDLIKRKIKPPILLRFMDVLQGRIASINRAFKSAISENDYPAKYQTFFPIKVNQQRQVVEAIASYGKRYNIGLEVGSKPELVAGISISSGNNLPIICNGYKDSEYIETVLYATAIGYDITLVIEKLFELEKVIELVKKTGIQPRLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIDLLEENGLLDRVKLIHFHIGSQITKIDKIKTALIEGARVYTELRKMGMGIEFVDIGGGLGVDYDGSKSSYFSSVNYSVEEYANDVIYQIKNICDDAGVECPNIISESGRATVAHYSVLVTNVLNTNTQRLTPDFEEELAAAEKLAPTVKKLVDIHKSIDRYSLREDYHDTVQLIQEAVSLFNLGYLTLNERAMAEWLYGKIIKKINSIVEKIKPIPEELQNFQLALRQTYFANFSLFQSIPDSWAIDQLFPIVPIQRLNQKPDVIASIADITCDSDGEITSFVGENGRTKFLPLHKIRKDEDYYIGFFLIGAYQEILGDMHNLFGDTNAVHITFNKKTGYMIDTVINGDACWESLKYVQYKGPEILKRVREHLEKGVAQRKVSIEESSHFIELLDRTLLGYTYLGE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: GCH1_RHOPA
Sequence: MDAKIKPIRGTNPAEGRPEFQPAELEPSEFLEVAVQPDQPRPSRAEAEAAVKTLLSYIGENTEREGLIDTPRRVVEAYDELFQGYHQCPKEVLERTFGETAGYDDFVLVRNISFTSHCEHHVMPFYGKAHIAYTPVERVVGLSKLARLVDIFARRLQTQEHLTAQIAAAIDEVLKPRGVAVLLEAEHTCMSVRGIAKKGATTFTSRYTGVFRDNPAEQARFMSMVRDRG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PTX4_HUMAN
Sequence: MGCSWRKTLSFFLVFVPIYLHGASSQEAAPVGPRKPFFERLRRLEEQFRRFQEVTWTHLQNIASNYNVSYNVDVRFRSLAEESQAVAQAVNRSQASVQGELAQLKAWVRKLQRRGRKVDTRLRALDLTLGERSQQRARERKAHKAQRDALQDSLARLEGLVHSQGARLAALEGRLPVAHPGTAALGPALVPTPTQPEELGPTSLKLQRDRQELRAASEHRGPPQDSSAPLQGRREPPASGSHRVLSGTAPKDPRQQAWSPQVPGEICGVGPTLVFPNASTRNVVFLSPGFVTALRALSFCSWVRTASGRLGTLLSYATEDNDNKLVLHGRDSLLPGSIHFVIGDPAFRELPLQLLLDGQWHHICVIWTSTQGRYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGGGFDSSEAFVGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCTCLERCP
What are the official names of this protein?
Pentraxin-4.
What are the subcellular locations of this protein?
Secreted.
Protein: UP1_URTPI
Sequence: DENENLYGPNENKAKAKDLTAGASYLTKEAGCTKLQAGCTMYQAYN
What is the function of this protein?
This toxin is a potent hemolysin devoid of enzymatic activity.  Its hemolytic activity is inhibited by sphingomyelin but not by cholesterol.  In erythrocyte membranes, it causes numerous cell membrane ruptures.  It also exerces cytotoxicity to different cell lines.  It exerces a positive inotropic effect.  Also causes hemorrhage and necrosis by dilation of the blood vessels in the skin, and vascular leakage of fluids and rupture of alveolar walls of the lungs.  Is a potent ichtyotoxin.  May act as a pore-forming toxin.
What are the official names of this protein?
Toxin Up-1, UpI.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: MOM4_CAEBR
Sequence: MDTSPHSKPSSSSASQSSHSPSPAPVTAPRKTRDSGLCMTQDIPEIPTHCIDNLNSHQLGRGTYGIVEKTRYRRSRNHEYRPAAIKYSSPIHLATLIREAKVMWALRDHSNIIKIYGLYRDARHGQGVVMEYMDCGSMSELIYDRKSIDYTIDHVASWLYQMASAVNTFHRNDQVHRDLKLQNMLLCDRYRTMKLCDFGTFTAMHQSMTSNRGTPITMAPEVFRCEEYNQKSDIYSIGIIMWQMIARNHPYNRNLSVPGLLYNVATASLRPPELDCNPILSDFYKQCWHDDPVSRPTAAECLQYFTALKTEYPNGNVPLADANTNRPVETPPPRVHRPSGLGSASGSGLGTNGRTPTASNHLNAPQAVNTHRRNRSETIQMKPELPYPVMPGEVAASSSGAFRGPRSQSEAKNLRDAGRSQSGQRHPHRNAPPIPIDDRRDSNESNEKDAIFMELLRNDDTRPVDPDARDEASLDIFHQHCSSNKEYADALLLKKEVLRAKHELLSRWPQHQRHVELLERQNYLEQEIAKLEYNSDDDFSITERL
What is the function of this protein?
Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos.  Stimulates the wrm-1/lit-1-dependent phosphorylation of pop-1 and plays a role in the initial nuclear accumulation of wrm-1 (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase mom-4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: GSH1_PSEA7
Sequence: MSDLLSRRLALLGAAANLPLLTECLHGIERECLRVDSDGKLALTPHPRALGSTLTHPQITTDYSEALLEFITPTETDVADTLGDLERIHRFASSQLDGEYLWSPSMPCELPDEESIPIARYGNSMIGRLKYVYRKGLALRYGKTMQCIAGIHYNFSLPEKLWPLLRQAEGSELAERDYQSAAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRPSQLERFDEHTLYLPYATSLRMSDLGYQNNAQAGLTPCYNDLQSYIDSLRKAVSTPYPAYEKIGTKQDGEWVQLNTNVLQIENEYYSSIRPKRVTYTGERPVQALAARGVQYVEVRCLDINPFLPLGIDLDEARFLDAFLLFCAFSDSPLLNGECSDATDNFLAVVKEGRRPGLQLRRRGQPVELKDWASELLERIADTAALLDRARGGEAHAAALAAQRAKVADPELTPSAQVLKVMRERGESFEAFSLRQSREHAEYFRQHPLAADEQARFEQMASASLAEQAELERDQDGDFDTFVAAYQASILGLISN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: K1C18_DANRE
Sequence: MSLRTSYSVRSSTSQVPVSQVSIKRTTNVPTYRAASIYGGAGGQGTRISSASYSGVRSGLGVPSMSSSIQVSASGSTGEIMGNEKMAMQNLNDRLASYLEKVRILEQANSKLELKIREALEKRGPDVHDYSRFQPIVDELRKKIFDATTNNARLVLQIDNARLAADDFRVKYESELSIRQGVEADITGLRKVIDDTNLNRMNLESEIEALKEELIFLKKNHDNEVMELRNQISQSGVQVDVDAPKGQDLSQIMEEIRAKYEKMALKNQEELKAWHESQITEVQVQVTQNTEALQGARSEVNELRRQIQTLEIELESQKNLKGSLEGTLRDTEMRYNMEIENLNTIILQLEAELTQLRGNIQHQTQEYEALLNIKMKLEAEIATYRRLLDGGDFKLQDALEEQKKVKVMTVTQTLVDGKVVSSSTETKERKL
What is the function of this protein?
When phosphorylated, plays a role in filament reorganization.
What are the official names of this protein?
Keratin, type I cytoskeletal 18, Cytokeratin-18, CK-18, Dorsal aorta proneprin kinesin-1, DreK18, Keratin-18, K18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: NGBR_DANRE
Sequence: MASLYEMVWRFLHALLYLQRAIVAWFRVHIWRWKLAVVDLLLPLALGFHNQKKTGPKGTRTSRRVRWGADGRTLEKLPLHVGLLVTEEEIHYTDIANLVVWCMAVGISYVSVYDNQGVFKRNNSRLMEEILKQQQELLGMGSSKYSVEILKNGTNKQEHQVLSCQSMVKVLSPDDGRLSIVQAAQQLCRAVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWHIRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK
What is the function of this protein?
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).  Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.  Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit nus1, Di-trans,poly-cis-decaprenylcistransferase, Nogo-B receptor, NgBR, Nuclear undecaprenyl pyrophosphate synthase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NQOR_RHORT
Sequence: MSDTTKVLVLYYSMYGHIDTLAKEIAAGVAEVDGVEVALKRVPEHMSAELLSTIHARTDFDTPIASVDELADYDGILIGTPTRFGNMAGQMRNFLDQTGGLWAKGKLVGKAGGAFTSTATGGGAETTLLSVYTNFLHHGMVVVGVPYGTPEMFDTSEARAGGPYGAATLAGGDGSRQPSDKERTIARFQGRHFAGVAKKLKG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: MIAB_PSYWF
Sequence: MSATLFDPKSIAVSNPVDTSTQASLAHASQPTGQAKKKVYIATQGCQMNVYDSEKMGNVLGDSHDMVVTDNIEEADVLLMNTCSIREKAQEKVFSELGRWRKLKEEKPDLVIGVGGCVASQEGDNIQKRAPYVDMVFGPQTLHRLPELYDKSTTQRNVKPKDRIGTVDVSFPSIEKFDFLPEPKVEGYRAFVSIMEGCSKYCSFCVVPYTRGEELSRPLDDVLAEIDSLAEQGVREITLLGQNVNGYRGEKDDGSICRFAELLHYVAHVDGIERIRYTTSHPLEFTDDIIEAYAKLPQLVSHLHLPVQSGSNKILAAMKRNHTIDVYINQINKLMAVRPDMHLSSDFIIGFPGETEEDFLDTLNLAKALDFDHSYSFIYSKRPGTPASELPDDVSLATKKERLAIFQKVIRDSTLKKTEEMVGKTLRVMVEEIADRYPDQLLGTADNTRSVLFKATEQQKTDLMGKFVTVKITDFVSPHMVRGELVDILD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ECO55
Sequence: MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_BDEBA
Sequence: MIKIVDYGLGNIQAFANLYKRLHIPVVVARTADELAGATKIILPGVGAFDHAMARLNESGMREILESLVQKDKVPVLGICVGMQMLANSSDEGVLPGLGWVPGRVREFRNIPGLEGIAQPHMGWNDVKPVVSSGLFKGLETDARFYFLHSFFFECQNPDYSLASANYGLEFSCAVANRNVYGVQFHPEKSHDFGMTLLKNFSEI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA1_BOSMU
Sequence: VLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSQGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.