PharMolix/UniProtQA huggingface dataset:
Protein: NCPP_SERP5
Sequence: MYHVVAATTNPAKIKAIQLAFEDTFGQDQCRIESVDVASGVSLQPIGNHETRTGARQRVMEARQVRPEADFWVGVEAGIEENMTFAWMTVENPQTRGESRSASLMLPETILQGIRAGRELGSEMATITGNAEVKRQGGAIGIFTDGRLSRTSVYHQALLLALVPFHNPIYQNHNNAAQK
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: TM216_MOUSE
Sequence: MAPRDKRLSSTPLEVLFFLNGWYYATYFLLELLIFLYKGLLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLGISVALTFPSAMMASYYLLLQTYVLRLEAIMNSILLFFCGSELLLEMLTLATFSSMDRI
What is the function of this protein?
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
What are the official names of this protein?
Transmembrane protein 216, Thymus atrophy-related protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: Y1556_METJA
Sequence: MMDKIIQTLTLTFTFLYYSIPMLIVGLFISQILIESNIIKKIYFIGKIFTRLANLPEECGIAITTSFIEPRMANIMLVDFYKKGIINKKELYISSLIDAFPAMLRHWDSLLPILLATLGFFGIIYFIILVLIGFIQTLIFMAIGKITLKNREYKEDNTDKKIKLNKDVVYTAFKNTIKYGIPIIRDITIASIITSFLIEFGFFDYITEIIKNKAYYLPLSVEEITVAVTQPINYIGAFVLAGEFLNRGILDEIEVVRALLLGSILSSIPALRFLAPYYIGIYGFKDGFNLMMISTLVRILITALFVIITLIL
What are the official names of this protein?
Uncharacterized protein MJ1556.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCOT1_PIG
Sequence: MAALTLLSSRLRLCASAYRSGGAWSQGCAGYFSTSTRRHTKFYTDAVEAVKDIPNGATVLVGGFGLCGIPENLIGALLKTGVKELTAVSNNAGVDNFGLGLLLQSKQIKRMISSYVGENAEFERQYLAGELEVELTPQGTLAERIRAGGAGVPAFYTSTGYGTLVQEGGSPIKYNKDGSIAIASKPREVREFNGQHFILEEAIRGDFALVKAWKADQAGNVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLVKGEKYEKRIERLSVRKEEDVKTRSGKLGDNVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGILGLGPYPLQNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTMLGAMQVSKYGDLANWMIPGKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDSKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQVTT
What is the function of this protein?
Key enzyme for ketone body catabolism (By similarity).  Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate), and produces acetoacetyl-CoA.  Acetoacetyl-CoA is further metabolized by acetoacetyl-CoA thiolase into two acetyl-CoA molecules which enter the citric acid cycle for energy production (PubMed:11327867, PubMed:17718512) (Probable).  Forms a dimeric enzyme where both of the subunits are able to form enzyme-CoA thiolester intermediates, but only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) and produce a new acyl-CoA (PubMed:11327867).  Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (PubMed:17718512).
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial, SCOT, 3-oxoacid CoA-transferase 1, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase, SCOT-s, Succinate-coenzyme A transferase, Succinyl-CoA:3-oxoacid CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NORR_SALSV
Sequence: MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVILEAQHFALSEDVLPAPPAESFLALPTCRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: AMYR_DROSU
Sequence: MFKFTFALALCVLAAGSALAQHNPHWWGNRNTIVHLFEWQWEDIAEECENFLGPRGFAGVQVSPANENIVSPGRPWWERYQPISYKLITRSGDEEQFADMVRRCNDVGVRIYVDVLLNHMSADFYGQAVGTAGTEADPATKSFPGVPYTAEDFHPSCQIYDWNDRFQIQQCELVGLKDLDQSRDHVRTKLIEFLDHLIELGVAGFRVDAAKHMASEDLEFIYGSLSDLKTEHGFPHNARPFIFQEVIDHGGQEVTREEYNSLGAVTEFRFWQEIGNAFRGNNAFKWLQSWGTDWGFFSSGQAFTFVDNHDNQRDGGAVLTYKIPRQYKMATAFHLAYPYGISRVMSSFAFDDHDSAPPQNAQEQLISPEFDSDGACVNGWICEHRWRQIYNMVGFKNAVRDTPVTNWWDNGDSQIAFCRGSKGFIAINNNLYDLAETLQTCLPAGVYCDVISGDLIHGSCSGKSVTVGNDGRAFVSIGSNDFDGVLAIHVDAKL
What are the official names of this protein?
Alpha-amylase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD1_RUEPO
Sequence: MAATVIDGKAFAARIRGQVAEHVAELKAGHGITPGLAVVLVGEDPASQVYVRSKGKQTVEVGMNSYEHKLDADTSEADLLALIDRLNGDPDVHGILVQLPLPGHLDEDLVINAIDPAKDVDGFHISNVGLLGTGQKSMVPCTPLGCLMMLRDHHGSLSGMDAVVIGRSNIVGKPMAQLLLGDSCTVTIAHSRTKDLADVVRRADIVVAAVGRPEMVPGDWIKPGATVIDVGINRIERDGKTRLVGDVHYDSCAQVAGAITPVPGGVGPMTIACLLANTLTACTRANKLTEPDGLTP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1/3.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PUR8_STAAR
Sequence: MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: RPPH_ORITI
Sequence: MDDKIKNYNNLPYRIGVGMVIINQKKEIFTGQRIDSARQYWQMPQGGIILGETYSKAVLREMKEEIGCNKAIIMAESRNWYSYHIPKFLVHKLWNSNFKGQKQKWFLIKFLGKDEDININTIYPEFSQWKWMNSNQLINNALPFKRKLYKAVINEFHIFLL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RF3_SHELP
Sequence: MSGYTVEVDKRRTFAIISHPDAGKTTITEKVLLFGQALQKAGTVKGKKSGQHAKSDWMEMEKDRGISITTSVMQFPYREALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEQRTIKLMEVTRLRDTPIVTFMNKLDRDIRDPIELMDEVENILNIACAPITWPIGAGKEFKGVYHLLRDEVILYQNGMGHTIQDSRVIKGLDNPELDEAIGSYAQDLRDEMELVLGASHEFDLEAFLKGELTPVFFGTALGNFGVDHILDGIVEWAPRPQPRESDQRNVEPDESKFSGFVFKIQANMDPKHRDRVAFMRVCSGRYEQGMKMHHVRIGKDVNVSDALTFMAGDRNRAEAAYPGDIIGLHNHGTIRIGDTFTQGEKLRFTGVPNFAPEMFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLDSNDLIVGAVGVLQFEVVVQRLKSEYKVEAIYEAISVATARWVYSKDAKKLEEFKRKCSNNLALDGGDNLTYVAPTMVNLNLSMERYPDIEFAKTREN
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_NITWN
Sequence: MTTGLDAELIEQGRKLFAGEWQFIWASPSIETLPPMSGLEVAFAGRSNVGKSSLINALTGRSALARTSRTPGRTQELIFFEGPKGVDVRLVDMPGYGFASAPKARIASWTSLIHQFLLGRATLARVYVLIDARHGIKDIDKTVLGALDRSAVSYQVVLTKADEVKVTEMAERIDITRTQLASHPAAFPDVLVTSSRTGNGIPELRAAMARLIGDHRR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: LEXA_SYMTH
Sequence: MPEPLTERQRQILQFIKDEIRTKGYPPSVREIGEAIGLSSSSTVHGHMTRLEEKGYIRRDPTKPRAIEVLDGSHTQLKRTIAVPVVGRVTAGQPILAQESIEDHFPLPADFVRADESELFFLTVQGDSMIEAGILDGDYVLVHRQQHANNGDIVVALIEDEATVKRFFKEQDHIRLQPENRFMDPIIVPDCQILGKVVGLVRRMG
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: G6PI_BORGP
Sequence: MINYKNLNELENFKILEGIAPEVLKTALTGKRIKEYDITIEGDSVHYNYASKQINENHLKIFQNLSDEANLIEKYKEVLNGEKINISENRKVLHHLTRGQIGKDVIEDNKENMREFFQSELEKIYNFAKQVHSGNIKSVNGKKFKNVVQIGIGGSSLGPKALYSSIKNYAKKHNLALMNGYFISNIDPDESEEVLNSINLDETLFIIVSKSGNTLETTANMQFLINKLKSNGIKEYKKQMTIITLKNSMLALEETGCLEYFFMHDSIGGRFSPTSAVGLALLTLCFTEKIVKEIIKGANKTDKKSLNKKVKDNAPLLAALISIYERNVLNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSVNRFNETINYKTVRIIWGGVGTDVQHSFFQMLHQGTDIVPMDFIGFNATQLKEDVISDNSSSNDKLKANLIAQIIAFSKGKENSNKNKNFKGERPSALIYSKELTPYAIGAILSHYENKVMFEGFLLNINSFDQEGVQLGKILANQILKNNAFEDEVIESYSKKILKQD
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRT_CRIGR
Sequence: MATRSPSVVISDDEPGYDLDLFCIPNHYVEDLEKVFIPHGVIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKRYNLKMVKVASLLVKRTSRSVGYRPDFVGFEIPDKFVVGYALDYNEYFRDLNHICVISETGKAKYKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_SALNS
Sequence: MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLVKAHEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGHWEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKATGLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELMELVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLATYFGTSPMDYGKNML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_BDEBA
Sequence: MTPQSQPQETAVALIPYVIEQTSKGERSYDIYSRLLKDRIIILGTAVTDEVANSIIAQMLFLEVDNPEKPIHLYINSPGGSVSAGLAIYDFMQFVKCDVATYCMGMAASMGSLLLTAGTKGMRYSLPNTRIMIHQPLLSGGGLSGQVTDIEIHAKELVKTKEKLTRIYETHTGRDYDTLRAAMERDNFMDPYQAKEFGLLDHVVESRKAKKG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_XYLFA
Sequence: MKRWYVVHAYSGFEKSVAQALRDRISRIEIQDRFGDVLVPAEEVVEMRSGQKRRSEHKFFPGYVLIQIETYYEGGVPRIDNECWHLVKETPKVMGFIGGTADRPLPISSDEADAILRRVQDGAEKPRPKVLFEPGQMVRVIDGPFNDFDGLVEEVNYEKNRLRVAVLIFGRPTPVDLEFGQVQKS
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: HEMA_CVBM
Sequence: MFLLLRFVLVSCIIGSLGFDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYSYGRCPTAADINTPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: NDHI_SILPE
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIMDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CP2CP_MESAU
Sequence: MDAVLVLVFILSSLVFLSLWRQSSERRKLPPGPTPLPIIGNFLQIDVKNISGSLTNFSKVYGPVFTLYLGMKPTVVLHGYETVKEALIDHGEEFAGRGDFPMAERINKGLGIVFSNGNRWKEIRRFSLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTNGSPCDPTFILSCAPCNVICSIIFQNRFDYKDQDFLTFMKKVNENVRILSSPWLQVCNNFPSLIDYCPGSHHKITKNVNYLKKYILEKIEEHQESLDIENPRDFIDYYLIKLKQANHNQQSEFSLENLTTTVSDLFGAGTETTSTTLRYALLLLLKHPHVTAKVQEEIDQVVGRHRKPCMQDRSHMPYTDAMIHEVQRFIDLIPISLPHAVTCDIKFRDYFIPKGTTVITSLSSVLHDNKEFPNPEVFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFKLKSMIHPKDIDTTPVVNGFASLPPSYQLCFIPV
What is the function of this protein?
Catalyzes the hydroxylation of tolbutamide and the N-demethylation of aminopyrine and benzphetamine.  Also has testosterone hydroxylase (16 beta) activity.
What are the official names of this protein?
Cytochrome P450 2C25, CYPIIC25, Cytochrome P450 HSM1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NORR_SHIFL
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFVGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRNGDEVILEAQHFAFPEVTLPPPEAAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: SELO_POLSJ
Sequence: MTAAPDTPSDPLDLAEPGLKWGNSFARLGPGFYTELQPTPLPSPYWVGRSQALARELGLEDHWLESAEALEVLTGNRSTAGSRPLASVYSGHQFGVWAGQLGDGRAILLGDLQTPAGPQEIQLKGAGRTPYSRMGDGRAVLRSSIREFLASEAMHGLGIPTTRALCVTGSDAPVRREDIETAAVVTRTSPSFIRFGHFEHFSYSNQHDRLKTLADYVIDGFYPACREAKQPYAALLEAASERTARLMAAWQAIGFCHGVMNTDNMSILGLTIDYGPFQFLDAFDPGHICNHSDPQGRYAYNKQPNIAYWNLFCLGQALLPLIEDQEQALAALESYKTVFPQALEARMRDKLGLVETQAGDRELIESTFKLLASNKVDYTIFWRRLCGFTPQSGHESVRDLFFDRESFNAWALQYSERVAGVDQGVRANLMLKSNPKFVLRNHLGEEAIRAAKLKDFSGVNTLLGLLQAPFDEHPGHDSFSDFPPDWASSIEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL34_STRP6
Sequence: MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CH60_SALAR
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPNITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4EBP_DICDI
Sequence: MSTTRAIPVSLKDRSDIDFSTSLGGTLYGTTPGGTKIVYDRNALLQYRNSPLSKTPPPQLAHITNTELNKKVEKSTTTPTTTTPPTTTAKPKPTNDDDIFPME
What is the function of this protein?
Regulates assembly of the eIF4F complex.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1A-binding protein homolog, 4E-BP.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: NFCP_HETCR
Sequence: MAGLLKESMRIKMYMEGTVNGHYFKCEGEGDGNPFTGTQSMRIHVTEGAPLPFAFDILAPCCEYGSRTFVHHTAEIPDFFKQSFPEGFTWERTTTYEDGGILTAHQDTSLEGNCLIYKVKVLGTNFPADGPVMKNKSGGWEPCTEVVYPENGVLCGRNVMALKVGDRRLICHLYTSYRSKKAVRALTMPGFHFTDIRLQMPRKKKDEYFELYEASVARYSDLPEKAN
What is the function of this protein?
Non-fluorescent pigment protein that is lilac in color.
What are the official names of this protein?
GFP-like non-fluorescent chromoprotein, HcRed, hcCP.
What is the protein family that this protein belongs to?
Belongs to the GFP family.
Protein: Y1530_STAAN
Sequence: MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
What are the official names of this protein?
Uncharacterized peptidase SA1530.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.