PharMolix/UniProtQA huggingface dataset:
Protein: Y0701_DICDI
Sequence: MKYQLSILGDESRLDPTTFNAFTVYMVNVTNLMTNRQWNIYRRYSQFHELDSEIKSAFPKIKLPKLPKKYIFKNSTNRELVEERKLLLQKYLKDLVKHEQIEDSDCLINWLVPQNEPAFTSLNNPDKSGYLIKEGHVIRSWKKRYFVLKDGLIYYFKHQSDQEPTGMIPVIGSQIKRIGETERKFSFQIIPKNETFFPTFSIQARDEQDCNDWIKAIELSQQHFQDQEQYRKQEEEERQKKNNGARIKKSGSFEFSTLTSASAPTSPVQSSSSTSNMLPSSYQFSSDGSNNNSVCSSIGALGPNNSNNNNNNNNNSYYYSHSSNNHNHYNHHNNNHNNSHHHHHHHNGLNRGSSQVSLSVNTTSSNSSGSSSSTSLSRRHPPQKSKSDLNLSSVLHSNIRIGIDESDELYILNNSISNENLSSMLEQPGSYQQPQHQQGGGGGGGGGGGNIVNNLPPLSLTQRHISNLSSRSNSNSSGSSSGSGSSSGSGPIGSGGVGGGLNQPVKTSSQQPHHRKSNSSNNPSYISHLHYLQPSNSSSSISSSSSSSSASSASSASPFSSLFTTINQYFNPKSNLPYSPPSSPILNANNNNNNNNNNNNNNNNNNNNDFNLNNNNNNNNNNNNGNTASGSSCNTTPNLLPAPTNVSPIQNRARSSPMTSLPLPNNLLIPIPVFSLNDEYNNINNNNSNIESNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTELVNNNIESNDNDNNNSNNNNNNNNNSNNSLDLINKPLVKIIEPKKKEKKSKSKSKVASISDFITSKKKEKDKEKEKDKEKEKEKEIGGNISTSTTPNKKNGTLRSRALTLPVKPNDSILGTTPHHNHQNNHHHHGDISSINIIREKFISKTTRFSSDGKPRFDINQKLVSTKLSVDKKIRNFIEVVIDDIDHEATSGGNLQKQQHTQLIANDIKKLANTVLNMSVYDQREKNTQIVQSIQTLFATAISNKEMTSLVSKFLFIFSEFSRVVDVLNPVEKNLTNVINKQLQSQQQQQKQNETTGTTTGTAGSSVNPLSFSSNSILVQQKRLSRSLQSFNEINHHYSSSYHEPIIYSSSLNQYNGINIGSGTPTTTSGDNTPLTNTATSSTVSSYSEPSLISSQNQLPLSQQPQPQPQQQQQLNDSSSFPTSPISSRNDLISSNSSIYEPPLSDVASQLIEQQQEQQQQQHQEQPLQPQQQQQQQPQPQPISTLVFDKANQRSSSPILEKKSILTDLLKENYQKETTNNNGIGNMIILSEYDKKLQKQQLYPNQHVIITEEMRNKPERSFVCRICEDTYTQSQLAKHTPFCALTNKHDFKNHSSHDERLYSILNLVKGIICDSFASPNNSEQYSYLIDDEIISQLGQQLEYLFNIPYGPVESPKQCQDVINRVQAIIDENSTDMALHVFGKRICKIIEEKKALFVQYSKFQNAAQTTTSKGKKWSMWGIIPFIKDIIPSPSSKVDSSSSSQISSPILSSPPPPMKQPPPQVIVPPSSLTTSSNTTSISIADFEIIKPISRGAFGRVYLAQKKKTGDLYAIKVLKKLDTIRKNMVNHVIVERNILAMVQNEFVVKLFYAFQSTDKLYLVMEYLIGGDCASLLRALGCFEEHMAKHYIAETVLCLEYLHKSAIVHRDLKPDNMLIDGLGHIKLTDFGLSKIGIIDDKKMEDSGNTNTNTHFNFSTSPTNTSMMDDSSTTGNPNGNGNTSLNSSQTNILSPYPQRKNTLKTPLKKPVKKVVGTPDYLSPEILLGTGHGQTVDWWALGIILYEFLTGSPPFNDDTPELIFQHILHRDREMEWPEEISSEAKDLILKLLNPDPYKRLGANGAYEVKTHPFFANVNWDTLIDQEMDNIFLPKPENNYDTDYFWDRQSMYDDEAEDDFLTINQSQPQHQSQHQSQPQSQPQPQSQNLGQNNNNSESNNNNNNSNSNVSGQNINNSVSSSSNNNGSGNLNNICNNSNVNANNNNSNGNLGNNNNNKNNNINNDNDKNKNNNSNVQNNNNNNNNNILQQSSSPSSTSSSLSNSSNNNHNGGRQINNSKDSDNSIGGGKNNSKIEDIEKDPITFGNFSFTNINHLKDMNNFFLKNKS
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0272282.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: RS13_BRUAB
Sequence: MARIAGVNIPTNKRVNIALQYIHGIGPKFAREIVTKVGIADDRRVNQLSDAEVLQIREAIDADYQVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PNP_ACTPJ
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKEVKEGQDFFPLTVDYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPVRPLFPEGFFNEIQVIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFINDQFVLNPTTSEQKISRLDLVVAGTDKAVLMVESEADILSEEQMLSAVVFGHQQQQVVIENIKEFVKEAGKPRWDWVAPEPNTALINQVKALAEARIGDAYRITEKQARYEQIDAIKADVIAQLTTQDETISEGAIIDIITALESSIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGEKSDRFLFHYNFPPYSVGETGRIGSPKRREIGHGRLAKRGVLAVMPTAEEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKGARMHILSVMEQAIPAPRADISDFAPRIHTMKIDPKKIKDVIGKGGAVIRALTEETGTSIDIDDDGTVKIAATDNNAAKAVMARIEDIVAEVEVNAIYKGKVTRVVDFGAFVSILGGKEGLVHISQITNERVERVADYLSVGQEVTVKVVEIDRQNRIRLTMKDLNNDTPVAENVTEEAEVSSEQQAEI
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB_AEQEI
Sequence: MSFSAAQVDTVRSNWCSMTADIDAAGYRIFELLFQRNPDYQSKFKAFKGLAVSALKGNPNAEKHIRIVLGGLGRILGALNTPELDVIYKEMASNHKPRGVMKQQFKDMGQAIVTALSEIQSKSGGSFDRATWEALFESVANGIGQYQ
What are the official names of this protein?
Globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DNA2_ACAPL
Sequence: MPSSVIMFTFLALTVLTAVMVGTSEAVSCMDNKNKPVDWFIVYKLPQDSASSKPVIREGYGQMYMDVNNQALKFSSTSLKDDDHAIAYTVDDIYKNHGKGNLAHVMYNDQPPAGEEIQSGLVGHTKGVLAFDGTSGFWLVHSVPKFPLPASKSYNWPDNAKRNGQTLLCITFKYDQFEKIGQQLKYNYPGVYDSDLPSKLVGKTPSIVDLVKNVHVTSPPWNRQLNLQSKSGQTFVSFNKASKWGEDLYKNWLATHFKSGLYCETWQNGGRNLNSSCEAGLNVYNVKKVSLSGGSDFKGTKDHSKWAVTTKSGLKWTCIGGINRQTSQMYRGGGAVCLENANVHKAFYDSVAEYEPCT
What is the function of this protein?
Hydrolyzes DNA with an optimum pH of 7. 2.  Is potently hepatotoxic.  It induces caspase-independent apoptosis (on rat liver cells) through the following procedure: binding to a specific receptor in the cytoplasmic membrane, entering the cell, entering the nucleus and degrading DNA.
What are the official names of this protein?
Plancitoxin-1, Plancitoxin I, Plan-I.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
What are the subcellular locations of this protein?
Secreted.
Protein: TBL1R_HUMAN
Sequence: MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK
What is the function of this protein?
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units.  Plays an essential role in transcription activation mediated by nuclear receptors.  Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
What are the official names of this protein?
F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EBI family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_ANADE
Sequence: MAAALSQGGTAITMKALLEAGVHFGHQTKRWNPKMKPFIFGARNGIYIIDLQKTVGLARNALRFVSDSVAKGGSVLFVGTKKQAQDAIREEASRSGQFFVTNRWLGGTLTNFKTVKQGIDRLKTIEKMAADGTYERLPKKEVAQLEREREKLEKNLGGIKELSRLPSALFVIDTKKEHIAVHEANRLGIPVVAVVDTNCDPEGIDYVIPGNDDAIRSIRLFTGKVAEACIEGKGRYSAWVAEHGGHDERREQEDRDAASERGHKDRRDRRDRRGGPRERREPREDRAAASANVEVVRKGEVAPAAAPEAAPAKE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: C82A3_SOYBN
Sequence: MDLLLNCLNLNTIAIASILSLIFLCLFLYRKNSRGKDAPVVSGAWPILGHLSLLNGSQTPHKVLGALADKYGPLFTIKLGMKPALVLSNWEMSKELFTTNDLAVSSRPKLVAVEVMSYNQAFVGLAPYGPYWRELRKIVTFEFLSNRRIEQRNHIRVSEVRTSIKELFDIWSNGNKNESRYTLVDIKQWLAYLTFNMVVRMVVGKRYFGVMHVEGKDKAQRFMKNIREFMNLMGTFTVADGVPCLRWLDLGGHEKAMKANAKEVDKLLSEWLEEHRQKKLLGENVESDRDFMDVMISALNGAQIGAFDADTICKATSLELILGGTDSTAVTLTWALSLLLRNPLALGKAKEEIDMQIGKDEYIRESDISKLVYLQAIVKETLRLYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKIHRDPSVWSDPLEFKPERFLTTHKDVDLRGHNFELLPFGSGRRVCAGMSLGLNMVHFTLANLLHSFDILNPSAEPVDMTEFFGFTNTKATPLEILVKPRQSPNYYETL
What are the official names of this protein?
Cytochrome P450 82A3, Cytochrome P450 CP6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: RL32_STRA5
Sequence: MAKPARHTSKAKRNKRRTHYKLTAPSVQFDETTGDYSRSHRVSLKGYYKGRKIAKANEAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DAPAT_DESHY
Sequence: MAQINENYLKLPGSYLFSEIARRVNEFKVQNPDADIIRLGIGDVTRPLAPVVVEAMKQAVEEMGRAETFRGYGPEQGYDFLIEKIIANDYAPRGVQLGMDEVFVSDGAKSDTANFQEIFGVDNIMAVTDPVYPVYVDSNVMAGRTGNYDIEKGQYGRIIYLPCTEEGDMKPELPTAPVDMIYLCFPNNPTGMTLTKEELKVWVDYARENKAIILFDSAYEAFIREEGVPRSIYEVEGAREVAVEFRSFSKTAGFTGTRCAYTVVPKDIMIYDSTGEGHSLNKLWLRRQTTKFNGVSYPVQAGAAAVYTEEGKKQIQATIDYYMENARIIREGLQEAGFKVFGGVNAPYIWMKTPGTMGSWEFFDKLMTEAHVVGTPGAGFGANGEGFFRLTAFGTRENTEKAIERIKARMK
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: ROLC2_LINVU
Sequence: MAEDDMCSLFFKLKVEDVTCSDDPEKHMKNASNERKPLIEPVENQLMDIDDEGGSVDHGLLYLYVDCRTMMCCFHRGSLPYNWMQGALLTNLPPYQHDVTLDEVNRGLKQALGFFGYADPMRTPYFTAFSFPGRVIKLNEQMELTSTKGKCLKFDLYASTHLRFKPDELVRHGECKFAIG
What is the function of this protein?
Hydrolyzes cytokinin glucosides thus liberating free cytokinins.
What are the official names of this protein?
Cytokinin-beta-glucosidase 2, Protein ROL C 2.
Protein: IL40_HUMAN
Sequence: MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANNANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGFRIGNGEVRGRKAAAM
What is the function of this protein?
Probable B cell-associated cytokine that plays a role in the regulation of humoral immune responses.  Involved in lymphocyte B cell development and immunoglobulin/IgA production.
What are the official names of this protein?
Protein IL-40, Interleukin-40, IL-40.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_CARHZ
Sequence: MRKIILLLIRFYQKFVSPILGSNCRFYPSCSQYTYEAIERYGVIYGSYLGIKRILRCHPFTPGGYDPVPEKKLRR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ITR2_MOMCH
Sequence: RICPRIWMECKRDSDCMAQCICVDGHCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 2, MCTI-A, MCTI-II, Trypsin inhibitor II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHDC_STAA1
Sequence: MSQAAETLDGWYSLHLFYAVDWASLRIVPKDERDALVTEFQSFLENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTYSYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYMLTMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMRFDETTARYGEFGSFFVGHLINTNEFDQFFAIS
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: PLSY_FRATN
Sequence: MNFLNFSILIFAYLLGSINSAIIVCYIFRLPSPRSVGSGNPGTTNVLRIGGKVPAAITLIFDILKGLVPVVIAKVLTGNEFITACTALYAILGHIFPIFFGFKGGKGVATLIGTLFGFSWILGLIFVITWLCVAIITRYSSLSALVATVIASFSVIFTSDLQVAAPFLIIAIIILVKHKGNIQRLISGQESKIGDKAKAKNDSN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLYA_RUMCH
Sequence: MYNIDTIKKIDSQLAEAIELEVNRQRNKIELIASENFVSDAVIEALGTPLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKQIFGAEHANVQPHSGAQANTAVYFAFLNPGDTILGMNLAHGGHLSHGSPVNISGKYYKVVPYGVREDNCYIDYDELRKTAKENSPKIIVAGASAYPRILDFKAFREIADEVGAILMVDMAHIAGLVAAGVHPSPVPYADVVTTTTHKTLRGPRGGMILCKQEYAKKIDSAVFPGNQGGPLMHVIAAKAVSFKEALTDDFKIYQQNIVKNAKALASALMEKGFKLVSDGTDNHLMLINLTNMNITGKEAQHKLDEVCITCNKNGIPFDTQSPFITSGIRLGTPAVTSRGMNEEDMKEIADLIHLTISDFENSRTNIIRRVEALCNKYPLYE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDP_MYCTO
Sequence: MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
What are the official names of this protein?
Probable acyl-CoA dehydrogenase fadE25.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: BAMA_ECO27
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGNLAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNYDPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PDX1_HUMAN
Sequence: MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
What is the function of this protein?
Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription.  Particularly involved in glucose-dependent regulation of insulin gene transcription.  As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element.  Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'.  During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation.  At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
What are the official names of this protein?
Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. IPF1/XlHbox-8 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: GUF1_ASPTN
Sequence: MRGCLQLARWLSAAPTRPAASHWPGLCAAPRFFSHSAILRASARTARAAASKPPSDLESRIAAIPIERYRNFCIVAHVDHGKSTLSDRLLELTGTIEPGTNKQVLDKLDVERERGITVKAQTCTMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAQGLELIPVINKVDLPSAEPERALEQMKQSFELDTENAVMVSAKSGLNVEKLLPTVVDKIPAPIGDCKKPLRMLLVDSWYDSYKGVICLVRVFDGEIRAGDQLVSFATGIKYYVGEVGIMYPNETPQTVIRAGQVGYIFFNPGMKRSKEAKIGDTYTKVGSEKAVEPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLMLNDRSITVQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKVLWKDGREEIVTSPAKFPDEDELRSKVAEIKEPYVLATLTFPDEYLGKVIELCESNRGVQQSLEYFTSTQVILKYELPMAQLVDDFFGKLKGSTKGYASLDYEESAWQTSNIVKLQLLVNKAPVDAVARIVHYSQIERLGRKWVTKFKEHVDRQLFEVVIQAAVGRKVIARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKRLRAVGNVVIEHKAFQAFLSK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LFTR_JANSC
Sequence: MAHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTLRRQIRFGGYSVHINRDFAGVLDGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGLAGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAGGFTLFDTQFVTDHLMSLGAFELPRSDYRAELSHALQLPADFMSLPEDVPLVV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_SHIB3
Sequence: MQQLQNIIETAFERRAEITPANADTVTREAVNQVISLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPD_ECO7I
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQTQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RADA_THEKO
Sequence: MARKKKVEDEVKELEEFEELDVEESLSSSDKQSKPEKKISALEDLPGVGPATAEKLREAGYDTIEAIAVASPLELKEIAGISEGAALKIIQAAREAANIGTFMRADEYMKRRTTIGKISTGSKALDKLLGGGIETQAITEVFGEFGSGKCFAKDTKVYYENDTLVHFESIEDMYHKYASLGREVPFDNGYAVPLETVSVYTFDPKTGEVKRTKASYIYREKVEKLAEIRLSNGYLLRITLLHPVLVFRNGLQWVPAGMIKPGDLIVGIRSVPANAATIEESEAYFLGLFVAEGTSNPLSITTGSEELKDFIVSFIEDHDGYTPTVEVRRGLYRILFRKKTAEWLGELATSNASTKVVPERVLNAGESAIAAFLAGYLDGDGYLTESIVELVTKSRELADGLVFLLKRLGITPRISQKTIEGSVYYRIYITGEDRKTFEKVLEKSRIKPGEMNEGGVGRYPPALGKFLGKLYSEFRLPKRDNETAYHILTRSRNVWFTEKTLSRIEEYFREALEKLSEARKALEMGDKPELPFPWTAITKYGFTDRQVANYRTRGLPKRPELKEKVVSALLKEIERLEGVAKLALETIELARRLEFHEVSSVEVVDYNDWVYDLVIPETHNFIAPNGLVLHNTQLAHTLAVMVQKPPEEGGLGGSVIWIDTENTFRPERIKQIAENRGLDPEETLKNIYVARAFNSNHQMLLVEKAEEIIKEKAESDRPVKLLVVDSLMAHFRAEYVGRGTLAERQQKLAKHLADLHRLADLYDIAVFVTNQVQAKPDAFFGDPTRPVGGHILAHSATLRVYLRKGKAGKRVARLIDSPHLPEGEAVFRITEKGVED
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: GNT1_CANAL
Sequence: MTSKSSSWKALLKNWEFKVAAFIGIYFLISHVVLETTDVVNEKGLKSHLKVLPEEVIDYYGKQPFSNVDKYAYMQYATNYDYLNLAIINFIHLRKANTKIPNLVIIYDEVLHYYASDKWSELYQVANQYKITLKAAPLIKASYQDDSNWAASFTKFHIFNQVEYDRIVFFDSDSMLVDIPNEIDFDNMESRFNHIDELFKIPQELSFASPQAYWLNNVVEGKSPRPRKNVEIPNKKRYSLRMKKLVNDLSIYQDFNLLPSLIYENHYFDNANHFFANHIMVITPSKNTFQELMRYIHNPWWWSITNRGSLRKPNDYDMEILNKYLNNELQRKRINVGILPHRVYGVLTGEFGEEWHERFVVEPQYLPFINKKSNKGWSPLEFFKKIKVVHFSDSPIPKPWEEENNEEHYNIKKIYCDKGDMEKFHKDYPVYKPRLTDDCDSVSIWNWFREQFYKERSGYWFA
What is the function of this protein?
N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
What are the official names of this protein?
Glucose N-acetyltransferase 1, N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GNT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein. Vacuole membrane; Single-pass type II membrane protein.