PharMolix/UniProtQA huggingface dataset:
Protein: AROK_SHEB8
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIEQRTGADIAWVFDVEGEEGFRRREAQVIADLSEKQGIVLATGGGSVQSKDIRNHLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPREVLENLAEIRNPLYEEIADVIVKTDDQSAKIVANQIIEQLGF
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_VIBVU
Sequence: MSLLEFFRPQKKTSASLAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVISKYVAIDPAMVDLTFEHKDDDISVLELNVKLPDEEK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: INS_DIDVI
Sequence: LVNQHLCGSHLVEALYLVCGERGFFYTPKAGIVEQCCNSICSLYQLETYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF2_CHESB
Sequence: MDATFWALVALIIFVGILLYMKVPGMLAGSLDARAERIKNELEEARRLREEAQQLLAEYQRKRREAEQEAKELVDAAKREAKLIVSDAKVKTEEYVSRRTALAEQKIAQAERDAVNEVRSRAVDVAVAAAGKLLAEKIDTKTGSELFKASLQDVKTRLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EX7S_SALG2
Sequence: MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPHC_PARXL
Sequence: MSIRSLGYMGFAVSDVAAWRSFLTQKLGLMEAGTTDNGDLFRIDSRAWRIAVQQGEVDDLAFAGYEVADAAGLAQMADKLKQAGIAVTTGDASLARRRGVTGLITFADPFGLPLEIYYGASEVFEKPFLPGAAVSGFLTGEQGLGHFVRCVPDSDKALAFYTDVLGFQLSDVIDMKMGPDVTVPAYFLHCNERHHTLAIAAFPLPKRIHHFMLEVASLDDVGFAFDRVDADGLITSTLGRHTNDHMVSFYASTPSGVEVEYGWSARTVDRSWVVVRHDSPSMWGHKSVRDKAAARNKA
What is the function of this protein?
Shows a preference for catechols with groups immediately adjacent to the hydroxyl substituents.
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase, 2,3-dihydroxybiphenyl dioxygenase, DHBD, 23OHBP oxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: YRAD_BACSU
Sequence: MNPIIEYLTGMNVLTDQIIAMDLLISAKNGVRNYAMAATEAGTPEVKEVLIRHLEEALDMHEQLSSYMMEKGWYHPWNPDEQVKLNLKNIDTAIQLPTL
What are the official names of this protein?
Spore coat protein F-like protein YraD.
What is the protein family that this protein belongs to?
Belongs to the CotF family.
What are the subcellular locations of this protein?
Spore coat.
Protein: CAPSD_BGYMJ
Sequence: MPKRDAPWRHMAGTSKVSRSGNYSPSGGMGSKSNKANAWVNRPMYRKPRIYRMYKSPDVPKGCEGPCKVQSYEQRHDISHVGKVMCISDITRGNGITHRVGKRFCVKSVYILGKIWMDENIMLKNHTNSVIFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATVKNDLRDRYQVMHRFNAKVSGGQYASNEQALVRRFWKVNNHVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSITN
What is the function of this protein?
Encapsidates the viral DNA into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  The CP of bipartite geminiviruses is not required for cell-to-cell or systemic movement.
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: UTP22_SCHPO
Sequence: MNGLKREHESSSSQDGSKTPETEYDSHVDSIEDIHSLASKRKKLNEKKENLEDLTLLKTSAFELKLNELIREISVRGKYFRHANTFVEKIKDLIFKTPVIPETNFWSACKNLEKDKKVIVPLAEPLSAKDTNLRASFVPPKTVTPGIFSCSNKFFLNPDGWSYDLFLEIPESIFTQKDYLNGRYFRKRAFYLTCIAKHLLENLGNEVKLEFVAFNDDIRRPILAILPESKGFAATGKRFTVFLIPTVRQIFPVSKLLPHKNAIRDFMEHEELKPTPFYNNSVLEEQNLLFYRDLVKKYSVNPQFLDACGLGSTWLNMRGFSSSIHSNGFGLLEWYVLMALLMSSTGLPAGNVLNTYLTAAQFFKSMLQFLSSKNLTSTLFKLNADSSNLKIGNGHLPTLIDCNTGFNLLGKMKQSFFEYFQASCRHTLNLLDENANYNFSKIFITHVNVPALEFDVSGCIPLEPKELEDPNFCRKTDLDSPYSLYLEYTWDLLQHALGDRVCQIILYSSICTSCSINESLKTKLPKLISFGLLLNPDALLRLVDIGPSPDDTVGSQKFREFWGEVSELRKFKNGSIAESVYWECSSPDERIRIPQRIIRHILNRHLGNNVGDRVSFRNEKFRVYVHSKISPNTDTYNEYVPVMEAYNEAVKSLINLSDIPLSIAEILPADESLRYSSSSVPFYESSTCAPIDVVFQFESSSKWPDELEGIQRTKIAFLLKIAELLEALDNVERASVGLENTDNPTHNCCFLQVLFSNNFTFRYRLRNDREIFFWKSLERNPSTKLSAQKGLYAYEHMFQFIPRHTLAIQAICQAHRSYSMAVRLAKHWFYSHLLTDHVTDEVIELLVASVYINSSSWRTTSSGETSFCRMLHFLAHWDWRFDPLIINSNGKLPHDVRHQATEKLESIRKQDVAIAHNAYYIITDYDFDGNHIGYYKPSKIIANRITSLARASLSELLKDTPNYKSIFKSSLDIYHVVIDVNINKLPMYRESNLTKYKNLQNMSSERPGFEPITEFVKELHRCFEDTISFFYNKKNPKVVTGVFNPRILANRPYRTNIDYPFKVVDKDTVVLDADVVCEEIRQVGGDLIRSIQLQLKA
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 22, U3 snoRNA-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the NRAP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UBIC_ECO27
Sequence: MSHPALTQLRALRYFTEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_MAIZE
Sequence: MVATKKTKKSTDNINNKLQLVMKSGKYTLGYKTVLRTLRNSKSKLVIIANNCPPLRKSEIEYYAMLAKVTVHHFHGNNVDLGTACGKYFRVCCLSIIDPGDSDIIKTTPGEQ
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: SRP54_SULIA
Sequence: MLENIRDAVRKFLTGSTPYEKAVDEFVKELQKSLISSDVNVKLVFSLTAKIKERLNKEKPPSVLERKEWFISIVYDELSKLFGGDKEPNVNPTKLPFIIMLVGVQGSGKTTTSGKLAYFYKRRGYKVGLVAADVYRPAAYDQLLQLGNQIGVPVYGEPNNQNAIEIAKKGVDTFVKNKMDIIIVDTAGRHGYGEETKLLEEMKEIYEALKPDDVILVIDASIGQKAYDLASRFHQASPIGSIIITKMDGTAKGGGALSAVAATGATIKFIGTGEKIDELEIFNAKRYVSRILGMGDIESILEKVKGLEEYEKIQKKMEDVMEGKGKLTLRDVYAQIMALRKMGPLSKVLQHIPGLGVMLPTPSEDQLKLGEEKIRRWLAALNSMTYKELENPSIIDKSRMRRIAEGSGLEVEDVRELLEWYNNMNKLLKMVKRRRGSIDKLFGGKIG
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: FRO5_ARATH
Sequence: MGNMRSLVKMLMVVLFLGWIFVWIMISTNRFQNIWTPKLAKYLKTTYFGPQGMNLVLLTVPMMFIAVLSCVYLHTQKQPSQTQSLYKCREWKVKGRMGRVMMVMNPLGIVTATELTFSLLFLALLVWALSNYLYLSYHVHLHNHDNANDMCRWQAKFRAFGLRIGYVGHYCWAFLFFPVTRASTILPLVGLTSESSIKYHIWLGHVSNFCFLVHTVVFLIYWAMVNKLMETFAWNATYVPNLAGTIAMVIGIAIWVTSLPSFRRKKFEIFFYTHHLYGLYIVFYAIHVGDSWFCMILPNIFLFFIDRYLRFLQSTKRSRLVSAKILPSDNLELTFAKTSGLHYTPTSILFLHVPSISKLQWHPFTITSSSNLEKDTLSVVIRKQGSWTQKLYTHLSSSIDSLEVSTEGPYGPNSFDVSRHDSLILVGGGSGVTPFISVIRELIFQSQNRSTKLPNVLLVCAFKNYHDLAFLDLIFPSDISVSDISKLNLRIEAYITREDKKPETTDDHKLLQTKWFKPQPLDSPISPVLGPNNFLWLGVVILSSFVMFLLLIGIVTRYYIYPVDHNTGSIYNFTYRVLWVMFLGCVCIFISSSIIFLWRKKENKEGDKDSKKQVQSVEFQTPTSSPGSWFHGHERELESVPYQSIVQATSVHFGSKPNLKKILFEAEGSEDVGVMVCGPKKMRHEVAKICSSGLAKNLHFEAISFNW
What is the function of this protein?
Ferric chelate reductase probably involved in iron reduction in shoots.  May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates.  May act in iron metabolism in reproductive organs (PubMed:16006655).  May function as root surface cupric chelate reductase and participate in the reduction of Cu(2+), for Cu(+) acquisition via Cu(+) transporters in response to copper deficiency (PubMed:22374396).
What are the official names of this protein?
Ferric reduction oxidase 5, AtFRO5, Ferric-chelate reductase 5.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVD_AGARV
Sequence: MISDNARAGMQQAPARSLFNALGFTPEEMKKPMVGIVSSFNEIVPGHMNIDKIVEAVKLGVAEAGGVPVVFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTECMAIAHQFDALVMVPNCDKNVPGLLMAAARLNLPTVFVSGGPMLAGHVKGRKRSLSSMFEAVGSYAAGTMTEDDVCEYENKVCPTCGSCSGMYTANSMNCLTEALGMGLRGNGTIPAVYSERIRLAKHAGMAVMDMYNKGIKARDIITKDAIMNALTVDMALGCSTNSMLHLPAIAHEIGFDFDISFANPISERTPNLCHLAPAGPTYMEDLNEAGGVWAVMKELADIGLLNTDCMTVTGKTVGENIKNAVNRDPEVIRPVDNPYSKTGGLAVLKGNLAPDGSVVKRSAVVDEMMVHEGPARVFDCEEDAIAAIKGGKIVEGDVVVIRYEGPKGGPGMREMLNPTSAIAGMGLGSSVALITDGRFSGASRGASIGHVSPEAAVGGPIALVEEGDIIKIDIPNMKLELDVSDEVLAERKAKWQPREPKVTTGYLKRYAALVTSGNRGAILALPGEQNA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TUG1_HUMAN
Sequence: MARPPPLPGLVGRRNGRAVDRAIGWRLFLLLWHPALGAQARPPRRAPGGRWRSRRVFLLVRRTRAAAYAFAIRRGVVRVVGGGGQLLRPAPGEAAAAAAAGFGAAGEAGVAGAGLEAWRHPSGPARTQLGGQEGAGGWLVVGFLLCLFLLMPP
What are the official names of this protein?
Taurine up-regulated 1 protein.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: HSLU_HELP2
Sequence: MSKLNMTPREIVAYLDEYIIGQKEAKKSIAIAFRNRYRRLQLEKSLQEEITPKNILMIGSTGVGKTEIARRIAKIMELPFVKVEASKYTEVGFVGRDVESMVRDLVNNSVLLVENEHKEKLKDKIEEAVIEKIAKKLLPPLPSGVSEEKKQEYANSLLKMQQRIAQGELDSREIEIEVRKKSIEIDSNVPPEILRVQENLIKVFHKEQDKVKKTLSVKEAKEALKAEISDTLLDSEAIKMEGLKRAESSGVIFIDEIDKIAVSSKEGSRQDPSKEGVQRDLLPIVEGSVVNTKYGSIKTEHILFIAAGAFHLSKPSDLIPELQGRFPLRVELENLTEEIMYMILTQTKTSIIKQYQALLKVEGVGIAFEDDAIKELAKLSYNANQKSEDIGARRLHTTIEKVLEDISFEAEDYSGQKVTITKELVQSKLEDLVADENLVKYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLAP1_HUMAN
Sequence: MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
What is the function of this protein?
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules.  Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN).  Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.  May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2.  This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling.  Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
What are the official names of this protein?
CLIP-associating protein 1, Cytoplasmic linker-associated protein 1, Multiple asters homolog 1, Protein Orbit homolog 1, hOrbit1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
Protein: UCR1_CAEEL
Sequence: MALRLAVSSALRPALNSQVRNASSAVSVKDVLASAPQAEVTTLKNGFRVVTEDNGSATATVGVWIETGSRFENEKNNGVAHFLERLIHKGTGKRASAALESELNAIGAKLNSFTERDQTAVFVQAGAQDVEKVVDILADVLRNSKLEASTIDTERVNLLKELEASDDYHQLVLFDMLHAAGFQGTPLALSVLGTSESIPNISAQQLKEWQEDHYRPVRMVLSAVGGGVSNVSSLADKYFGDLSNEYPRKVPQVDGTRFTGSEYRYRNDNVPHMYAAFAVEGVGYAHKDALALQIANQFIGQWDVTHATSRTAASRLVQKIGHDHGVHNLQHFNINYKDTGLFGIYFVADAHDLNDTSGIMKSVAHEWKHLASAATEEEVAMAKNQFRTNLYQNLETNTQKAGFNAKELLYTGNLRQLSELEAQIQKVDAGAVREAISRHVYDRDLAAVGVGRTEAFPNYALTRAGMSWWRM
What are the official names of this protein?
Cytochrome b-c1 complex subunit 1, mitochondrial, Ubiquinol-cytochrome-c reductase complex core protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: INSC6_ECOLI
Sequence: MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYGRAKKWIAHAPLLPGDGE
What is the function of this protein?
Involved in the transposition of the insertion sequence IS2.
What are the official names of this protein?
Transposase InsC for insertion element IS2K.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: ZN319_HUMAN
Sequence: MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHSGLVKCSICEKTYKPAEAAEPATTAAPSLPAAPAPSTVTPAEQADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 319.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AUSJ_PENBI
Sequence: MLSRSHSNATMSTTRHRLLATASRFVETLESLDMDAMLAVRSSTCLHHMCCPSFRNYSITNDQTREALPQWKATIKKYKFGVLDDSQTLVDEQARKVMIRAETAAETTVGDYNNEYVFILRMTEDCNAVDEIWEFYDTIRLRDLRHRLEAGHVPIGVDAPAPFTTTASPAAL
What is the function of this protein?
Part of the gene cluster B that mediates the biosynthesis of the fungal meroterpenoid acetoxydehydroaustin (PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (By similarity).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (By similarity).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG then modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:29076725).  The cytochrome P450 monooxygenase then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:29076725).  The hydroxylation catalyzed by ausR permits the second O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:29076725).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end product of the Penicillium brasilianum austinoid biosynthesis clusters is acetoxydehydroaustin (PubMed:29076725).
What are the official names of this protein?
Austinoid biosynthesis clusters protein J.
What is the protein family that this protein belongs to?
Belongs to the trt14 isomerase family.
Protein: FPG2_MYCTU
Sequence: MAGTPQPRALGPDALDVSTDDLAGLLAGNTGRIKTVITDQKVIAGIGNAYSDEILHVAKISPFATAGKLSGAQLTCLHEAMASVLSDAVRRSVGQGAAMLKGEKRSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGGKALADRRMSRLLK
What are the official names of this protein?
Uncharacterized formamidopyrimidine-DNA glycosylase-like protein.
Protein: CRCB_FRAP2
Sequence: MGLLLILVGIGGGLGAMSRFALTQATASISKQIPIGILLCNIIGSLIIGMMAAFLIQTKLFNEDISTYVRSLFVTGFLGGFTTFSSFSLDILNLLQRGEALLAISYILVSVIVSLIAVILGFYFIMGIYR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1169_ACTSZ
Sequence: MSIQSNEILETIRMVADQNFDVRTITVGIDLHDCISCDIDELNRNIYRKITTVGKDLVETANILSAKYGVPIVNQRISVTPIAQIAAATKADSYVSVAQTLDRAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMKTTDIVCSSINIGSTRAGINMDAVKLAGETIKRTADITPEGFGCAKIVVFCNAVEDNPFMAGAFHGAGEADAVINVGVSGPGVVKEALANSHADTLTEVAEVVKKTAFKITRVGELIGQEAAKMLNIPFGILDLSLAPTPAIGDSVARILETMGLTVCGTHGTTAALALLNDAVKKGGMMASGSVGGLSGAFIPVSEDEGMIAAAESGILTLDKLEAMTAVCSVGLDMIAVPGKTPAHTLSGIIADEAAIGMINGKTTAVRIIPVTGKDVGESVEFGGLLGYAPIMPVKEGSCEIFVNRGGRIPAPVQSMKN
What are the official names of this protein?
UPF0210 protein Asuc_1169.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RBFA_ENTFA
Sequence: MANYRDRRVGQEIMREVNDILNKRIRDPRVQGITITDVRVTGDLQQATIYYSLLSDLASEQQKAQQGLDKAKGLIRKELGQRLTLYKTPELIFERDESVQYGNHIDELIRKLNQGE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5691_ARATH
Sequence: MATTNPGYLRCKEERNNKSFFMVLQSVDVSSENLVESCRYMTMGLAVKRALPYDFVRSFTDKELSLGISKNPTFYYMEKSGWEKFVRDNTLGTLDGKEMMQPPQPRAFLASSSRIRRFRTEQGEDDKKEEVVSESSNRGRTTAAESVGRKLKLGKKAAEESQESKRTEKVVRARRDEAGASSSTAVEFTAVFQPAYLYNLRIRSSVKDQMPVEKTIFKVHHPNGKKFWNVVYLGSYGAFSGGWQCLVKEYPLVVGDIYLQVYIHQTGGATSSCLQTLMMMDVRVRRNY
What are the official names of this protein?
Putative B3 domain-containing protein At5g46915.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_METM6
Sequence: MQKSEGFRSKTRYKLQKHPRQKGMAPLTRALKCYTEGDRVHVVLDPSVQKGMPHPKFHGKTGVVVAQRGRSFLVRVKDGGKYKDIIARPQHLRESKL
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: APOA1_NEOSC
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDEPQSPWDRVKDLATVYVDVVKDGGRDYVAQFEASALGKQLNLKLLDNWDSLSSTVAKLREQIGPVTQEFWDNLEKETEVLRQEMNKDLEEVKKKVQPYLDEFQSKWHEEVELYRQKVAPLGAELREGARQKLQELQEKLSPLGEELRDRARTHVDALRAQLAPYSEQLRERLAARLQALKEGGGAALTEYHAKASEHLSALREKAKPALEDLRQGLLPVLENFRDSLLAAVDEATKKLNSQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.