PharMolix/UniProtQA huggingface dataset:
Protein: CHO2_UNCRE
Sequence: MTDPAVSPLGCDGLRERRTQAPKETITPASLDPLMSKMRTDESSTVEPEKTTFGRTPDGTVFTVPHTRDMVSQLLSPSEPKNLSDILVLSILALHLLLLRALPTSFRIPVFAFIFLSWRAAYNIGIGWLLHMQSNHRTLVLWARKLQLFVDPSTGENRHPLLYRFIKRELETKIPENYSFENAPIEYNTWLVFRRVVDLILMCDFTSYCLFAVACGSRPVDEGFFMMLLRWSTGLSLVLFNLWVKLDAHRVVKDFAWYWGDFFYLIDQDLTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISILAHAAQFAFLVLVENPHIEKTYNAPPPRKRVVDPDTALHEEPGSRSNSFNSDATPPMSLPGTTQPRSTHALVGSIDFHRVTDLSVLLIHLLFFAFTMVTPSTPIYRFLFVLNAALWRIWYSAGIGYILDRQSARKSWTRHFVKFGEGQDEAWRQWQGIYHLSMTTCYASFIAAAWKMYTLPQDWGYGLAILRHVLGASLIALQIWTSMSIYESLGEFGWFFGDFFYDESPKLTYSGIYRFLNNPERVLGLAGVWGAVLITNSRAMIFLALLSHTLSIAFIQLVERPHMQKLYGRSLRRDAGLVKSIKRSLPNSLKQFQGSVDKILDESIDFVEEVIDTARPKLAAGVNTFVKDTTALFHKYPARITITRLEPDLAGYELKDYALSVEGTELTQFNKSGGETKEKSQSSRGSENLVFEYGAPIKVKWTAPLNHSKKDWVGLYMVTHNSSREITKVSSQGRWVATNEGAFDSSTSEIGLKSSDISEHSQGKNGKSREVASGEMVFSGDKLWWNQGVFEFRYHHNGKHNVMAISRPFEIRIAKFDENEIPLDNHGVVRPAIEAALLPIVQNCLDRDADIAPQNSEEAFGSQVDRDSKYAKRVVFAVQHMFGIEFAPEVVCADGSVRNLAWRICNAKKVLAPYSMSRSSGTTTPVQED
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYGA_CAUVN
Sequence: MSREKPKSFQSLILTLHDYWSRQGCVILQPHDVEVGAGTLHPATVLRALGPKAWNAAYVQPSRRPGDGRYGENPNRLQHYYQYQVILKPNPENMQDLYLGSLEAIGLDLRTHDIRFVEDDWENPTVGAWGLGWEVWCDGMEVSQYTYFQQVGGLDVNPVAGELTYGLERLAMYVFGVDNVYDLPFNDPDSPLGATTYGDVFLENERQQSEANFHGFDVAVLKQQFEQMEEQVPLMLARSYQDKALVLPAYDMVLKASHLFNLMNARGAIAVAERASYIGRIRDLCKMCASAWVEQQEAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODA_RHIME
Sequence: MSLKVQWKLCWENQLERADHQELSEFFRKSYGPTGAFHAKPFEGGRSWAGARPERRAIAYDSVGIASHMGVLRRFIKVGETDLLVAELGLYAVRPDLERMGIAHSVGALTPTLRELGVPFAFGTVRHAMRNHVERYCQNGMASILTGVRVRSSIAEVNADLPSTRTEDPLVVIFPVGRPLNEWPPGTLIERNGSEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (nod) that stimulates mitosis in various plant protoplasts.  The N-acyl substituent is a C16 unsaturated or an omega-1 hydroxylated fatty acid in R. meliloti.
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_VIBVU
Sequence: MAAKETKELPPFEYPQGYHCIAGVDEVGRGPLVGDVVTAAVILDPNNPIEGLNDSKKLSEKKRLALLPEIQEKALAWAVGRCSPEEIDQLNILQATMVAMQRAVEGLAVKPDLVLIDGNRCPALPMDSQAVVKGDLRVAQISAASIIAKVVRDQEMEELDKQYPQFGFAQHKGYPTKAHFDAIEKHGVIEQHRKSFKPVKKALGIEE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_PSYA2
Sequence: MREYNLFTSESVSEGHPDKMADQISDAILDAILRQDLHARVACETLVKTGAVILAGEITTTANIDVERIVRDTVNGIGYHHSDLGFDGETCAVINMLGKQSPEIAQGVDRADPEEQGAGDQGLMFGYASNETEVLMPAPIEYAHRLMERQSELRRAGELPWLRPDAKAQITLKYDGSKPVAIDAVVLSTQHDPSISQADLQEAIMESIIKQVLPAELLHAGTRYHINPTGKFVIGGPVGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAVRYVAKNIVAAGIADRCEVQVSYAIGVAEPTSISINTFGTNKISNDEIIRLIRTHFDLRPYGITRMLNLLQPMYQQTASFGHFGRQGSETAFTWEKIDKAEILKADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_ALIF1
Sequence: MELTPREKDKLLLASAGMIAERRKARGLKLNYPEAVALICFEIMEGARDGRTVADLMNYGRTILTADDVMEGVPEMIPDVQVECTFPDGTKLVSIHEPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_SYNPW
Sequence: MASLLPQSERETLSNTLPHWQVEAGRLKRNWQFKDFSEAFAFMTRVALLAEAMQHHPNWSNVYNRVSIELTTHDLGGLSDLDVQLARSIDALC
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: HOSA_ECOLX
Sequence: MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKPGIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDAADKRRRFVWLTAEGEKVLAAAIPIGDSVDEEFLGRLSAEEQELFMQLVRKMMNT
What is the function of this protein?
Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation.  Regulates fliC expression by directly interacting with fliC promoter (By similarity).
What are the official names of this protein?
Transcriptional regulator HosA.
Protein: RRG9_KOMPG
Sequence: MILSKLSFRHVKSRISQPYVNISVLRPYSSKKSANKWILPNLTKLNETKEHTVTKQKRITKSGLDESDRELLVSLNSGPRMHADWRKMKTLPEWKRQKFALVEKLQGSKWNPKKKLSRDTIEGIRLLKEKLPELKADYFAEQFQVSPEAVRRILKSRWEPTLEERENIEERWKRRGVKHLQLKIKEQLLKTVKEKGEKSEDDRKTIESEFEDDVIVNK
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VE26_NPVOP
Sequence: METAQPPISYAPPKRGAVCAYVRTVVTTTTVSDSGGNNEDRLTQIVAQLQRTRLNFSKLSQLQRRRVRNMQKLIRKKNSVIANLAARLTTQKKTKHFAVTIRKNVIHTTSGSEQFVRQRVLELCANGGEQVFCARRADCARDRRRVAEALATALGAGVVASAANKRFEIEDEEKLVSAKLIVQQVLHDGDHSDTCAD
What is the function of this protein?
This protein is required for viral late gene expression.
What are the official names of this protein?
Putative early 21.8 kDa protein.
Protein: FBVR_MYCTO
Sequence: MAMVNTTTRLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLDRA
What is the function of this protein?
Catalyzes the F420H(2)-dependent reduction of biliverdin-IXalpha at C10 position, leading to bilirubin-IXalpha, a potent antioxidant.  As biliverdin-IXalpha is produced in high amounts in macrophages infected with M. tuberculosis, its reduction by Rv2074 may play a role in protecting mycobacteria against oxidative stress, aiding the persistence of M. tuberculosis infection.
What are the official names of this protein?
F420H(2)-dependent biliverdin reductase, F-BVR.
What is the protein family that this protein belongs to?
Belongs to the F420H(2)-dependent biliverdin reductase family.
What are the subcellular locations of this protein?
Cell surface. Secreted.
Protein: UREG_STAA9
Sequence: MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_VIBC1
Sequence: MAVKKPENMTFEATIEELDSLVDQLENGDLALDDALRKFERGIALARAGQTKLSDAEQRVSILLSEDDEAPLSDFNPESE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEIS1_XENLA
Sequence: MAQRYDDLPHYGGMDGVGLPSSMYGDPHAARSMKSVHHLNHGPPLHPHQYPHSAHTNAMPPSMGSSVNDALKRDKDSIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFSKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLEGKMPIDLVIDDRDGGSKSDSEDLTRSAPLTDQPSWSRDHDDAASIRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSIASPSTGDDDDPDKEKKRNKGRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPIGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
What is the function of this protein?
Induces expression of a number of neural crest marker genes as part of a heterodimer with isoform b of pbx1, to specify neural crest cell fate.  Binds to a highly conserved region in the promoter of the neural crest marker gene zic3.
What are the official names of this protein?
Homeobox protein Meis1, XMeis1.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Relocation from the cytoplasm to the nucleus is dependent on interaction with pbx1 isoform b.
Protein: MATK_NICTO
Sequence: MEEIQRYLQPDRSQQHNFLYPLIFQEYIYALAHDHGLNRNRSILLENPGYNNKLSFLIVKRLITRMYQQNHFLISTNDSNKNEFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKIFKSHNLRSIHSTFPFLEDNFSHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEYWNLNSLITSKKPGYSFSKKKQRFFFFLYNSYVYECESTFVFLRNQSSHLRSTSFGALLERIYFYGKIERLIEVFAKDFQVTLCLFKDPFMHYVRYQGKSILASKGTFLLMNKWKFYLVNFWQCHFSLCFHTGRIHINQLSNHSRDFMGYLSSVRLNSSMVRSQMLENSFLINNAIKKFDTLVPIIPLIGSLAKANFCTVLGHPISKPVWSDLSDSDIIDRFGRICKNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRAFLKRSGSELLEEFLTSEEQVLSLTFPRASSNLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FTSK_RICBR
Sequence: MLYYVNKFLSNSKVQAVILGIIGLATISMLVSYKLDDPSFNSATTGYTNNLLGIFGSYLSDFLYQFFGVAAFIIPLSCFIWGKNCWQQKYRKSFIRISVMLLALFSTAALLSNFDLEFVPSNGGGAAGIIIFHFLKQFTNQLHLLLVFFTFIIFVVLFEIKFTSLSSFIIKLGKFLAYKIQTFFYNLFSQLTLPKLFSGKANNKIKITPSYTKPVNEKIRFTEEPKPIMAKPAPVNPIKFFNKPTVPKISQNDATALPPISLLRNPENHHIKGASSSELKQKAEELLTVLNDFGVKGQIINIGQGPVVTLYEFEPAAGTKTSRVVGLSDDIARSLSALSTRIAVVPGKNVLGIELPNKQREFFCLKELIETPEYQDTSTLLPLVLGKDLAGKPLIADLAKMPHLLVAGTTGSGKSVGINAMIVSLLYRYTPEECRFIMIDPKMLELSAYDGIPHLLTPVVTEPAKAVVALKWAVKEMENRYRMMSNIGVKNIAGYNTKIQEAVKEGRIIEKSIQTGFDPETGRPIYETVAMNMEKLPFIAVIVDEMADLMLVAGKDIEMLIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEQGSEQLLGMGDMLFMGNTSKITRVHGPFVNESEIEQITEYLKETGTPEYISAVTEQSDEDDSSIDIGDGTSDEVLYKKAVQIVRDERKSSISYIQRSLRIGYNKAANLVEKMEKEGIVSPPNHTGKREILLPER
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: CTOMT_SOLLC
Sequence: MGSTANIQLATQSEDEERNCTYAMQLLSSSVLPFVLHSTIQLDVFDILAKDKAATKLSALEIVSHMPNCKNPDAATMLDRMLYVLASYSLLDCSVVEEGNGVTERRYGLSRVGKFFVRDEDGASMGPLLALLQDKVFINSWFELKDAVLEGGVPFDRVHGVHAFEYPKLDPKFNDVFNQAMINHTTVVMKRILENYKGFENLKTLVDVGGGLGVNLKMITSKYPTIKGTNFDLPHVVQHAPSYPGVDHVGGDMFESVPQGDAIFMKVMSKSLAEAWILHDWSDGHCLKLLKNCHKALPDNGKVIVVEANLPVKPDTDTTVVGVSQCDLIMMAQNPGGKERSEQEFRALASEAGFKGVNLICCVCNFWVMEFYK
What is the function of this protein?
O-methyltransferase that catalyzes the conversion of catechol to guaiacol (PubMed:22103597).  Involved in the production of guaiacol in fruits (PubMed:22103597).
What are the official names of this protein?
Cathecol O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: EFTU_OCEIH
Sequence: MAKEKFDRSKSHVNVGTLGHVDHGKTTLTAAITTVLAKHGGGEARAYDQIDGAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRNVGVPAFVVFLNKTDMVDDEELLELVEMEVRDLLTEYDFPGDDLPVIKGSALKALEGVAEYEERILELMAAVDEYIPTPERDKEKPFMMPVEDVFSITGRGTVATGRVERGEVKVGDEVEIIGLAEDASKTTVTGVEMFRKLLDYAEAGDNIGALLRGVSREDINRGQVLAKPGSITPHTNFKAEVYVLSKEEGGRHTPFFSNYRPQFYFRTTDVTGVIELPEGTEMVMPGDNIEMTVELISPIAIEDGTRFSIREGGRTVGSGVVSSIQK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SALTY
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDEVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RNH_PSEP1
Sequence: MSDSVEMFTDGACKGNPGPGGWGVLMIYKGVEKELWGGERETTNNRMELMAAIQGLMSLKRECEVVLTTDSQYVMKGINEWMVNWKKRGWKTAAKEPVKNADLWQQLDEQVNRHKVTWKWVRGHIGHPGNERADQLANRGVDEVRAQR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRPM
Sequence: MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVSLHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKKDREKVTATK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CAMJE
Sequence: MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFARNYTDIDDKILKKMAQSGQTLEEITEFYIKSYEEDMRVLNVLDPDFKPRATHYITAMLDLIKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENISRLSNEVQKRNESDFVLWKFDENFYESEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKLANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLENAKKRLDKFYRLKKRLDLGEISDFDVLNDIGIKSEIAKQILEILNDDLNVSKALALLDDFISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDATLYFQWGVSKEEREEIEKLILERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANM_YERE8
Sequence: MTQIYHQYKKKLSTKVILLSALTLCITFSLPYANAERYPDVPVAFKYGTGARVDNHLYVGLGSAGQSWYRLDTDKASSGWQKIADFPGQPREQAVTVALSGKLYVFGGVGKNSASDTQVRALDDVYQYDPQTNQWQRLATRAPRGLVGTAATTLNGTQALLLGGVNKAIFDGYFTDLAAAGGNETQKNAVVNAYFDQAPADYFYNRDVLMYDPAKNQWKSGGQVPFLGTAGSAITAKKGDLILINGEIKPGLRTAAVWQGKTQGTELKWQQRPDLIGAEKGAVQEGLAGAFAGVSHDVVLVGGGANFPGSWQQFNAGQLYAHQGLKKQWQQPIYALVDNQWQVAGKLPQPLAYGVSIQDKDKVILLGGETSDGVATSAVTQLSWQGGKLHLE
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GCY18_CAEEL
Sequence: MLKTLLFILIFFNIPIIAIEEIPDIKENGEKSSYTQFDNGAKLEVNKEHKRVIKIGHIGAVGVMPNDARILNISKENLIEEGLVGDDIEFEIVSRQACSESFEGVAVAAELYHVHQVRAFIGPYCAAELEAVTKMATFWNIPIISYSSVPNAVSDRSVYKTLARVSSKNTNSIAEATVALLLHYKWLKVAIATNTGSTAFERVSIFEEIMHREGVTIVKKVMFDENTDANEMMNSGQLGDLAANARIIICLFSSTKELSKEFMQATYTMRMNNAEYAYIIPWLQSGTKDLTPWIGADGEMLQRVKDHYANAIIVDDVNGFDDSVVSSFVEKIEKHGMQKSDIDVTNINGYLHLFDSLKLYALAIRKVLNETDNEAYVTNGQFIWNRMRRMKFEGVVSRSSSEENKDAGAIGTVLMDDVADRAPIFSAFYISPNRDKVMKMVNMESELISNCDGLKNKSGCFQLKINDIKSGFWPSEDGSMPLDEPICGYRGQRCSYLLEISVGSLIILLILISVVFFFLFRYCENKQLEKMPWRIFHDDLQFIDEEQVKSMMSVGSVTTKLSNIQTGQKQHAIIGVNTHTTYHRYKQRRPIKFIKEDMQLLTQMKQAVHDNLNPFLGAAFNEKEEMLVLWKFCSRGTIQDIIYNANVVLDEKFHGAFVRDITLGLEYLHASPIGYHGSLTPWCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSLPFRDNTNISELVDYLADGSKTVSPEIQNQMGLHPDLNALLRDCWSENPEIRPSIRRVRLNTEMVLKTKGSLVDQMMKMMEQYANNLEKLVAERTGMLEEANIRADQLLTQLLPAYVANELKMGRSVAPKLYSSATILFSDIVGFTTICSGSTPLEVVNMLNGLYTGFDECITRNKSYKVETIGDAYMVVSGIPEENEYNHSRNIANTALDMRQYLTGYQIPHRPTHRVRCRWGFHTGSVAAGVVGLTCPRYCLFGDTVNVSSRMESTGTPGMIQMSEEAHMHIRAHHPVFTTTERGEVQVKGKGTCRTFWLEDRVGDASTTNYIQNVEGV
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Regulates thermotaxis responses in AFD sensory neurons.  May regulate AFD neuronal activity such as calcium responses to temperature gradients (PubMed:16415369).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-18.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Note=Localizes exclusively to the sensory ending, known as cilium, in AFD neurons.
Protein: HIS8_CALS8
Sequence: MFREVIRTISPYIPGKPISEVKRELGLEKVIKLASNENPLGPSENVKKAIKESLDDLSLYPDGNCTELKLKLAKKLNVKPTQIIFGAGSDEITQLIASIFINPGDNSIMARPSFPRYETVTKVMGGIPIEIPLKNYTHDLEEFSKHINERTRVIWICNPNNPTGTIVKKDELYNFIKSVPSEIAVVVDQAYKEYIDDPEYPDAIHWLDEFKNLIVLQTFSKIYGLASLRIGYAIASEEIIEKLNRVRPPFNVNHVAQIAAIAALDDQEHIEKAKELNKKSLEFFYKSFEEMKLPYIKSYGNFVMVDVTKDAVEVFKKLLLKGIIVRPGDIFDMPTYIRVTTGLESDNMEFIKALKEVL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ATP23_CHAGB
Sequence: MATPPPPQLSSTSTQPPSPSSASSNPQQPSPPKTQPPLPRFLDNDPARTGYDPTVKWWLNYFRIMTGQVTREGVEHYREDRYKANEARDCARCEADRAYLFAYSPTIRFLRDKVAALNGTLDETNVVCRRCPARVAEDGRVVRQGGGFSPEHGILICANEMRDRSHLEDTLAHEMVHAWDHLRWKVDWSGGGNLRHAACTEIRASMLSGECRWTRETMTRGNWTLTQQFQNCVRMRAIQSVMARPTCRDDVHATKVVNEVWDSCFSDKRPFEEVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: JIP5_LODEL
Sequence: MGKKKNNSSNAAHVLESSVAPILELNFTDPLFTTAAHPTKPLLISGFATGHLYCNSYNGEKLEELEQVNREKAIERQQKAYEAGTITHVNKSVSQLKSKWWTTFNDIKDVPSKGEELVNVQTNWKTKRHKGSCRHAIFDPRTDCLGDYLYTCGTDNIIKKAATETGKVVGKVDVVADYSSAKDKLTKLCHSTTHPFLLSGTEDGHVLVYDSSNLGGTNKIKFKVELAHDDSINHILSMPAVSPYHYLTLGSTTLSHIDIRKGIITQSDDQEDELLAMSYTTDELSENKNDTVLVSHGEGIITIWKNSKNKLADQLTRIKVNKTASIDAIVPTMNNDDENGMASSVWCGDSEGLLHRVNYKRGRVVETRLHSVARGKSDAVDEVGVLDIDYDYRLISAGMDSLKIWSNRYSDDQEEEEEEEEEEEEEEDSVSGTDSGSDEESFSDISSVDFDSENNDDGEELLDKEQWEDVEDEDIPVGTDGSTRNEENKDNTKSEYILPFKRKRRDFSEVITKPKKKLIDINKLTKPSKKEDDGDDNNKSLQEQEKAEEVPQFKKQKVKEKKVTAKQLRNMQKHEHGIRKFEGL
What are the official names of this protein?
WD repeat-containing protein JIP5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL34_MARN8
Sequence: MKRTFQPSVLKRKRVHGFRARMATANGRKVLSRRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.