PharMolix/UniProtQA huggingface dataset:
Protein: IFT80_HUMAN
Sequence: MRLKISLLKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETTQIVKLPDDIYPIDFHWFPKSLGVKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQIKIWSKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRPLYNSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHVVFAHVVEQHWEWKNFQVTLTKRRAMQVRNVLNDAVDLLEFRDRVIKASLNYAHLVVSTSLQCYVFSTKNWNTPIIFDLKEGTVSLILQAERHFLLVDGSSIYLYSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIRDKADEKIIFLFEASTGKPLGDGKFLSHKNEILEIALDQKGLTNDRKIAFIDKNRDLCITSVKRFGKEEQIIKLGTMVHTLAWNDTCNILCGLQDTRFIVWYYPNTVYVDRDILPKTLYERDASEFSKNPHIVSFVGNQVTIRRADGSLVHISITPYPAILHEYVSSSKWEDAVRLCRFVKEQTMWACLAAMAVANRDMTTAEIAYAAIGEIDKVQYINSIKNLPSKESKMAHILLFSGNIQEAEIVLLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLETFGKQETNKRYLHYAEGLQIDWEKIKAKIEMEITKEREQSSSSQSSKSIGLKP
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
What are the official names of this protein?
Intraflagellar transport protein 80 homolog, WD repeat-containing protein 56.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Basal body and ciliary axoneme.
Protein: SEC9_CANAL
Sequence: MGIKKMFQKKEPTEQEIREELSRVGISTRSNNTRQEKFGAFKNYAQERANMKPQLGPVGGNPYANINPGTNNNNNNPYANDNGNNSTGNPNNNSNSNNGGNPYGGGVTNNNPYGGSGGNGRGSSPSPYAPTTSTTTRSSNPYGNNNGSRSSQNTSSPYAKSTNNSSYSNSPYSGSTVNNGNRGGHSNNSNSSAGGNPYAAGGRSSQSQNSRDNVYTAPATRTSTRQTQGYGGGDTDSTLDLNAIPSHQMFDNKKPIKRNQQSSQQPANDYNLDLNDEYGEEEDLNLDISEVPEEQQQINSEDEEVEAIKQDIKFVKQESVQSTRNTLRMAQEADASGTNTLGMLGSQSERLYNAEQNLLLAETQTQIADEKVKELKRLNRSIFIPANGNPFNKKSRLRQQEEKIKNQKLQEKYIRENNRQEMFASEQRIKQGITNNSTNNDVYNKYQDEKNLSAAKRYQFENDSEDDDMEKEIASNLNQIDQYAKKLKGLANTMGTEVDNQNTRLKKIEESADKLDINVHMNTTRLNNIR
What is the function of this protein?
Late secretory t-SNARE protein required for secretion and proper cytokinesis.  Plays an important role in the secretion of virulence-associated extracellular enzymes and vesicle-mediated polarized hyphal growth.
What are the official names of this protein?
Protein transport protein SEC9.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: LOVG_ANOGA
Sequence: MSKVSGAGEEKLKVLALHGYRQNADSFKSKLGSFRKMLNKYVEFVFVSAPHPAAPLEAVGGEPDPNQRSWWFNKDDRTFKGTNQGGPAYGFDESLRLVERTWQAEGCHGLLGFSQGACFVGLLCDLSARGMTTMKPQFAVVASGFRSGSLVHLNYYENKVQIPSLHIFGETDEIITKDMSEALAETFLDPEVVTHPGGHYFPAQASLKETYVDFFRDQLQQHLEAKELQNATEENSFHLEGQEEAEESALQPVHEGLQNGSDSDSD
What are the official names of this protein?
Esterase AGAP003155.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: RPOZ_STRSY
Sequence: MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAKPTQEFTSVKSTLRALEEIESGNVVIHPDPEAKREAVRRRAEEAKRLAEEEERKIKAQIAKEKEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ASK10_YEAST
Sequence: MSDYFSSRPSQTLTPMGNKPSGGGGGDDASSIHSKSSQYLMDILPDSMTLNESVSSIVANNQAKEFILPETDERSPYFINVPIPKAQPTSTTETKKPLAGDEAIDGQFVKEYPTDILVDRFYKWKKILKGLVIYLREVAYAQEQFARINYQLKGSVKFPFLTDIDETTNTITDPFTTAPRGPKKAQPAQKKVGLTDSEQFQMQMQQEQQENAVQAPTDESKMSLAPHEYKPVQTTESDNTSAASGFVKFGSGSIQDIQVILKKYHLSLANQQFKISKEITSTVIPKLEELRKDLRYKITEIKDLHGDFKTNIGAHIQLTSQLLKKYIAAVKFMNAHGIGNDRASPTNKKPHKLDPKHDPYLLKLQLDLQLKRQVAEETYLQEAFINLQSSGLQLEKIIYTKIQHALLRYSALIDSEARLMIKNMCQELQHGIISKPPAFEWDNFVTQHPSCLLNWKSNDPIPPPRKVSDVIYPHMKSPLAKCIKAGYFLKKSELLPTYHQGYFVLTSNYIHEFQSSDFYNLSSSTPNSTKSSAYSSSVSIADTYANANNAKANNHHRQASDVHNSSTTTGGTAGANGIRGIRKKSYLAPIMSIPLNDCTLKDASSTKFVLVGKPTLNENADVRKSSSSTYLSGSSQASLPKYGHETAKIFSKAPFHKFLKGSKPKNKNTKSSELDQFYAAAQKESNNYVTWTFKIVSPEPSEEELKHFKRWVQDLKNLTSFNDTKDRIKFIEDRVMKSHRFKAGHMSRNSVNIGSHTPCLTDSTFTLQDGTTTSVNLKGRAEKPQYIHIQNNSLADFDGNGFRSKVNTPAIDDYGNLITVERRPAQSPHQYSDYMATSGNTTPSYSSGSRPQSMYNGYNPAVSITSNGMMLQQSTANNNTNPTTNLRHQRNISQTSSLPGFSYTSLSLPVNSPGSSNSESSSGGYFAIPLHGNNNNNNYTQRNSEGSSPCYNDDQIRQQQQPLQMQPLSRTSSSSVNVTAMRSTSAGNSITANAPVVPKVMVNNQNVKTVAADQSATAPSSPTMNSSVTTINRESPYQTLKKTNSTGNVPCLTAEKTHAHPAFYKRGNNSAQNLTTSSSTASRVHPIRKHKKNVSFSSLNSLMFSKKGANHGGNLMTNQFMSGGIQEDDGDSTNNDTIKLNQSIYS
What is the function of this protein?
Positive regulator of FPS1 glycerol channel required for the glycerol efflux.  As a component of the RNA polymerase II holoenzyme, is required for SSN8 destruction in response to oxidative stress but not heat shock.  Required for cell survival in response to heat shock independent of SSN8.
What are the official names of this protein?
Activator of SKN7 protein 10, Regulator of the glycerol channel 2.
What is the protein family that this protein belongs to?
Belongs to the RGC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Displays diffuse cytoplasmic localization, but very rapidly aggregates into punctate spots that appear near the cell surface in response to hypo-osmotic shock.
Protein: RL22_STRMU
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKNVADAIAILKFTPNKAARIVEKTLNSAVANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVEEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: KSG6_ARATH
Sequence: MTSIPLGPPQPPSLAPQPPHLHGGDSLKRRPDIDNDKEMSAAVIEGNDAVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRLMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNARLPNGRPLPPLFNFKQELSGASPELINRLIPEHVRRQMNGGFPFQAGP
What is the function of this protein?
May mediate extracellular signals to regulate transcription in differentiating cells.
What are the official names of this protein?
Shaggy-related protein kinase zeta, ASK-zeta, Shaggy-related protein kinase 2-2, AtSK2-2, Shaggy-related protein kinase 23, AtSK23.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Protein: VIRB7_BRUSU
Sequence: MKKVILAFVATAFLAGCTTTGPAVVPVLDGKPRVPVNKSVPAKPPLAQPNPVDTYED
What is the function of this protein?
The VirB system could be required for the establishment of the replication niche in the host.
What are the official names of this protein?
Type IV secretion system putative lipoprotein virB7.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARNB_PSEU2
Sequence: MSQTFLAFSRPSIGDEEIAAVTRVLRSGWITTGPECQKLEEEFAARVGARHAVALSSATGAMHVALLALGVGPGDEVITPSQTWVSTANMICLLGATPVFVDVDRDTLMTSAALIEHAITPRTKAIVPVHYAGAAFDLDPLYALADRHGITVIEDAAHAAGTAYQGRPVGQQGTAIFSFHAIKNMTCAEGAMLVTDNARLADRVRQLKFHGLGVDAYDRLTLGRKPQAEVMEPGFKYNLADINASIARVQLQRLDAINAQRQALASHYLERLANSPVLPLALPRYAQQHAWHLFILRIDPERCGLDRDAFMKALQARNIGTGIHFIATHLHSYYRKRFPDVRLPDTEWNSSRLCSIPLFPDMSLDDVERVVGAIESTLESSH
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, Polymyxin resistance protein PmrH, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: KI2L4_HUMAN
Sequence: MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKDAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI
What is the function of this protein?
Receptor for non-classical major histocompatibility class Ib HLA-G molecules.  Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M).  In decidual NK cells, binds peptide-bound HLA-G-B2M complex and triggers NK cell senescence-associated secretory phenotype as a molecular switch to promote vascular remodeling and fetal growth in early pregnancy (PubMed:23184984, PubMed:29262349, PubMed:16366734).  May play a role in balancing tolerance and antiviral-immunity at maternal-fetal interface by keeping in check the effector functions of NK, CD8+ T cells and B cells (PubMed:10190900, PubMed:16366734).  Upon interaction with peptide-bound HLA-G-B2M, initiates signaling from the endosomal compartment leading to downstream activation of PRKDC-XRCC5 and AKT1, and ultimately triggering NF-kappa-B-dependent pro-inflammatory response (PubMed:20179272).
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DL4, CD158 antigen-like family member D, G9P, Killer cell inhibitory receptor 103AS, KIR-103AS, MHC class I NK cell receptor KIR103AS.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane.
Protein: APAH_PSEF5
Sequence: MATYAVGDLQGCLEPLQCLLEQVAFDPARDRLWLVGDLVNRGPQSLETLRYLYSIRDSLVCVLGNHDLHLLAVWRNVERLKKSDTLREILEAPDCEELLQWLRQQKLMHYDEARNIAMVHAGIAPQWSLKKAQKCAAEVEEALRDDNLFDPFLDGMYGNDPAKWDSDLKGVTRLRVITNYFTRMRFCTSDGKLDLKSKEGLDTAPPGYAPWFSHKERKTRDLKIIFGHWAALEGHCNEPGIFALDSGCVWGGAMTLLNVDSGVRLTCDCDAQGRTAALSPDPLPAPAKR
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: FABH_SERP5
Sequence: MYTKILGTGSYLPVQVRTNADLEKMVDTSDEWIVSRTGIRERRIAAADETVATMGFHAAEKALEMAGVAKEDIGLIVVATTTSTHAFPSSACQVQQMLGIKDCAAFDLAAACAGFTYALSVADQYVKNGAVKHALVIGADVLSRTLDPEDRGTIILFGDGAGAVLLGASEEPGILSTHLHADGSYGGLLTLPFKDRQDQDKPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRSALDWLVPHQANLRIISATAKKLGMGMDKVVVTLDRHGNTSAASVPAALDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_LISMO
Sequence: MAKEDVIEVEGVVQETLPNAMFNVELENGHKVLATVSGKIRMHYIRILPGDKVTVELSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_YERPG
Sequence: MSTYLIGDIHGCLDELLALLAQVNFDPQQDTLWLTGDLVARGPASLDVLRYVRSLGPAVRMVLGNHDLHLLAVYAGISRNKPKDRITPLLDAPDADELINWLRRQPVLQVDDQLKLIMAHAGITPQWDIETAKMCAREVEAVLSSDSYPLFLDAMYGDMPNNWSPELTGLARLRFSTNALTRMRFCFPNGQLDMICKDTPENAPAPLKPWFDLPRLVDPEYSIIFGHWASLEGKGVPEGIYGLDTGCCWGGDLTLLRWDDKRYFTQRAFKAEAEINNNNGFAAGEAVQH
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: SC58_TITOB
Sequence: KKFGGFLXXI
What are the official names of this protein?
Toxin To58, Toxin Tc58.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIE_BURM9
Sequence: MVAPVNGIASALQQMQAMAAQAAGGASPATSLAGSGAASAGSFASAMKASLDKISGDQQKALGEAHAFEIGAQNVSLNDVMVDMQKANIGFQFGLQVRNKLVSAYNEIMQMSV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: LDHA_SCEWO
Sequence: MSLKEKLIVNVHKEEQPHAHNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMLDLQHGSLFLRTPKIVSGKDYAVTAHSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPDCKLLVVSNPVDILTYVAWKISGFPKHRVIGSGCNLDSARFRHLMAEKLGIHPLSCHGWIVGEHGDSSVPVWSGVNVAGVSLKGLHPDMGTDGDKENWKQVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAETIMKNLRRVHPVSTMVKGMHGINDDVFLSVPCVLGYSGITDVVKMTLKSEEEDKLRKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_CLOK5
Sequence: MYKKIDNNKSFVQMEKDILKLWQDRKVVEKSFNSNKDGEYFTFYDGPPTANGKPHIGHVLTRVIKDLIPRYKVMKGYKVLRKAGWDTHGLPVELEVEKSLGISGKPQIEKYGVEDFIKKCKDSVFTYVSQWRKMSDRIGFWVDMDDPYVTYDNHYIESEWWALKQIWDKNLLYKGHKIVPYCPRCGTALSSHEVSQGYKDVKETSVYVKFKIKNEDKYILAWTTTPWTLPNNMALTINKSYDYVEVINDGEHLILAEGLLEKLEGEYEVVKKFKGEEMLGIEYEPMFNFTPFEGKAHYVVHGDYVTLTDGTGIVHTAPAFGEDDSITCIKHNIPMINSVTTQGKFKDEVTPWKGLFVKDADPKIIAYLKEKDILYKAEKFTHSYPFCWRCDTTLLYYPRDTWFIRMSAMRDKLIRNTNDTNWYPDNIRTGRFGKFVEGVIDWGLSRERYWGTPLPIWECECGHRECIGSIKELREKGINVPDDIELHKPYIDGVKLKCDKCHKEMERVPEVIDCWFDSGSMPFAQHHYPFENRELFEKNFPAQFISEAVDQTRGWFYTLMAISTVLFDKSSFENCLVLGHVLDKHGLKMSKHKGNVLSPEVVLENEGADATRWYFYTESAPWLPSRFYEEAVQDSQRKFLGTLWNVYSFYVLYADLDKFNPLEYSHFVSENVMDKWVISRLNSLIKITEGNLDNYRITQAAESIGNFVDELSNWYVRRNRTRFWNEELAEDKVGAYVTLYNVLNKLCLIAAPFVPFMTEEIYQNLVLSLNKNVPESIHLCKWPEYDLNLVDSDLEKNMEECYKIVKLGRSARNAANIKNRQPLSEMLISVKTLPGYYGDIIKSELNIKNIVFNADLSKYVNFNIKPNLPVLGKKYGRMIPKIKQSISSMNQMDLAGKINNNEVVKIKIDETEIELNSENLLITMEGLEGFAFAGEGSTGIVLETTITEELKEEGNLREILSKIQNMRKESGFEVADKIKLYVSDNEKLEEVVKKFEAQIKKETLAVEVAYNENREYSGCNINGEKFNIAVEVLK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX19B_MOUSE
Sequence: MCPPVSVRHGAKGMSCLYGAWLYHLVHGEQMKICFACFKAAFLVVKNMLEMGDWEEGVWDAEPMELSEASSEPEEWPGLSGGEGQGHLPHGISVSAGSGAQGPQPVPTELGPQEAVPLDLGPEDAEWTQALPWRFDGLSPCSHWLIPPLSWWEIFNVSPSPGQPVLLELSPTWPMDPLEAEAWLVGLKFVFLLGGFDAICYMLSMTPCWAVRTRVQRWQVLLDPGDVRVAQLQNAPEQQDLHRWKLSVLESSELGMELVPADCSLQKGGFKVHSYLPWHNSTPESWSREPGERLLVVEVVSLRELPCFRSPSPDPHN
What is the function of this protein?
May be required during spermatogenesis, probably by participating in the repression of retrotransposable elements and prevent their mobilization (Probable).  With its paralog, Tex19. 1, collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins.  Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:28254886).
What are the official names of this protein?
Testis-expressed protein 19.2, Testis-expressed protein 19B.
What are the subcellular locations of this protein?
Cytoplasm. Note=Was initially reported to localize in the nucleus.
Protein: DNAJ_NEIG1
Sequence: MSNQDFYATLGVARAATDDEIKKAYRKLAMKYHPDRNPDNKEAEEKFKEVQKAYETLSDKEKRAMYDQYGHAAFEGGGQGGFGGFGGFGGAQGFDFGDIFSQMFGGGSGRAQPDYQGEDVQVGIEITLEEAAKGVKKRINIPTYEACDVCNGSGAKPGASPETCPTCKGSGTVHIQQAIFRMQQTCPTCRGAGKHIKEPCVKCRGVGRNKAVKTVEVNIPAGIDDGQRIRLSGEGGPGMHGAPAGDLYVTVRIRAHKIFQRDGLDLHCELPISFAMAALGGELEVPTLDGKVKLTVPKETQTGRRMRVKGKGVKSLRSSATGDLYCHIVVETPVNLTDRQKELLEEFERISTGLENQTPRKKSFLDKLRDLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOTB2_DROER
Sequence: MNSATSLMCFALLLISPLCMGYTAEDREADSRRVAEIIKNSQDDNSKINSIQELLDIYKRLYPSLTPEERESIDNFVNEHTDEVLVDGVPSQGGRKTKFAGKILSEATKGVATGFFEELGSKLAGLFTG
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot B2.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLU_HELPJ
Sequence: MSKLNMTPREIVAYLDEYIIEQKEAKKFIAIALRNRYRRLQLEKSLQEEITPKNILMIGSTGVGKTEIARRMAKIMKLPFVKVEASKYTEVGFVGRDVESMVRDLVNNSVLLVENEHKERLKDKIEEAVVEKIAKKLLPPLPSGVSEEKKQEYANSLLKMQQRIAQGELDSREIEIEVRKKSIEIDSNVPPEILRVQENLIKVFHKEQDKVKKTLSVKEAKEALKAEISDTLLDGEAIKMEGLKRAESSGVIFIDEIDKIAVSSKEGSRQDPSKEGVQRDLLPIVEGSVVNTKYGSIKTEHILFIAAGAFHLSKPSDLIPELQGRFPLRVELENLTEEIMYMILTQTKTSIIKQYQALLKVEGVEIAFEDDAIKELAKLSYNANQKSEDIGARRLHTTIEKVLEDISFEAEDYSGQSVTITKELVQSKLGDLVADENLVKYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_ALIF1
Sequence: MTINFDTATQTLEAEGLRCPEPVMMVRKTIRKMEDGETLLIKADDPSTTRDIPSFCRFMDHELIAEDTDSLPYRYLIRKGLSK
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT4B_ARATH
Sequence: MADTGKGSASASCNDRCGCPSPCPGGESCRCKMMSEASGGDQEHNTCPCGEHCGCNPCNCPKTQTQTSAKGCTCGEGCTCATCAA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable).  Functions as metal chelator of copper (Cu) and zinc (Zn) (PubMed:18287486).  Plays a role in storing and distributing Zn ion in seed (PubMed:22014117).
What are the official names of this protein?
Metallothionein-like protein 4B, MT-4B, EC protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane.
Protein: DNAA_JANMA
Sequence: MENFWQTCSAQLEQELTPQQYSAWIKPLAPLDYEDGTLRIAAPNRFKLDWVKTQFAGRITSIAAQFWDMPVDVQFVLDPRLASAKKPTTSASVAPIQSDDVPASVLEPIPSNATDHTPRRDQSRINTALTFDSFVTGKANQLARAAAIQVANNPGSSYNPLFLYGGVGLGKTHLIHAIGNQVLADNPDVKIRYIHAEQYVRDVVTAYQRKGFDDFKRYYHSLDLLLIDDIQFFGGKSRTQEEFFYAFEALIAAKKQIIITSDTYPKEITGMDDRLISRFDSGLTVAVEPPELEMRVAILLKKAVQEGVTFSDDVAFFVAKHLRSNVRELEGALRKILAYSRFHGKDITIEVVKDALKDLLSVQNRQISVENIQKTVADFFNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIAADRGKSPECNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ACIBS
Sequence: MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVYTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIREGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLNAASFYQIVQAFAQSK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.