PharMolix/UniProtQA huggingface dataset:
Protein: RM39_DROME
Sequence: MSAATKLHKTSWCALRQLQQYRTKANFSGSSASLAKRNDLFNQEQRRQRDAVGRIDKIEVRYLGLPEDVTLVMNGNISTPFNCAQHLSEGHCKRSALALIDGSVPWDMHRPLQESCTLQLLNFHVSEPHVVNKAFWRTCSFMLGAALNRAFKPEANLQLHSFPGPNIKSGSFVHDIVLQTQNWEPGKEEMRALSAEMVKLAAQDLRIERLDVQQDLAQEMFKDSKYKSEQLPSISQQTNGRVTLYRLGDHIDISRGPMVASTSFLGKCVISAAHKVAEEGPSGAFYRIQGVALPSGFQLNHVAFGVLEERSKKPSPARLPNEPFEEQQQLQLS
What are the official names of this protein?
39S ribosomal protein L39, mitochondrial, MRP-L39, MRP-L5.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL39 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DABA_RHOPT
Sequence: MLMTKPPVPQLNLTAVHEAAERAARAIPPLWPLESSVAVNPFLGQIGEPLAVAAARLRRVAGAAVTMPRAWYAERIASGELSDVDLAAAIDAATPTTRPLTIAELKRAAQMEIAPPQALPTVADLASAVSGFDWTGFVAERISAWASGYFDRGQALWAAPKGPNAYAAWRLTATHDLTPEIFSITGFAADVAAAPESADAALIRAVEQLGLSEAASESYFHRLLVGLGGWAQLARYRLWQAELSGSTDTTVTDLLAVRAVWDSALLRKYQPQIAAEWTDAINGYAQPLQPTEDDQINAILQDAVERAAQRKLQTVLTASSQPKPEDRPALQMAFCIDVRSEPFRRALESLDPRIRTLGFGGFFGLPIAHRRFASDVVEARLPVLLPPRVTTSCSGHTHAHEANDRAKRVAARAKRAWGRFKLAAISSFAFVESMGPVYVAKLLSDGLRPGTRTTNTDPVPQFDPPLALGARVDTAEAVLRAMSLTGPFAPLVLIAGHGASVVNNPHASALHCGACGGFPGDVNARLLAGLLNDPEVRTALAGRDIAIPADTLFVGALHDTTTDAVTLYDADHHSPAHAAALAQTRDWLATAGALTRSERALRLPRAATGGAIARRARDWAEVRPEWALAGCRAFIAAPRSHTSGRDLQGQAFLHDYDWRKDTDFSVLELILTAPVVVASWISLQYYGSTVAPETFGAGNKLLHNVTGGIGVVEGNGGLLRSGLPWQSVHDGERLVHQPLRLSVLIEAPHEAISTILDRYPEVRALFDNGWMHLLALDDNGRMHWRYGGDGGWERADNPPANQRVASFE
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZNRF2_PLAF7
Sequence: MFNFRNLPLFDKDNSKDTDDIKNFINSYEGIYFSSSNKFINVFLDKILIIDPSSLNVITINTDLYVVDFLFNEKNKNLIVLGKGKNSLICSVYNIRECNFTLLKKIQLSKNINNIKKTLIAKCNEYIITLENKKITFYFLNKDYSINQSELIEDGKELIENIYLSKNHILLVIKNSYVYIYQLDIKNSHISYTLIDSFNLNLSYLRESINNKKKHINKINDVSNNDPKKDNNEKNTSSNNITHNNYNDISNNNNNNNNINGVKDHINNNTLENNDEPILSIYNEDLNVLYICQNMYNVLFVLNLNNLSFEFILLENKIINLFSCKFYLILLKEVNKKFFLHIYIIYEDMKLLVSTLLLNEPISNVIFFNNLFCLLIEEEISKPEIKVDKFYFYEQLKLKLHSKLDGDALKILKRDHVTNNINICKQEEKKYKLKNEQKDVEIYNKNNTVDSTNNTIYNSEVNHYKYITNDFFLNEDVNTDIKKELYNLNHTKDNINHDTLKKQTNQNDITMSLSKDEKNNDTNKFFNENMFTLNKFFKNCRNQIKIILKERNINEIINMFKKKKLYQWLIKYANLNKNYQIININFIHKIYADFLFEKEQYENAIYEYIQTINYLETSYVIHKYLNLDLYEYLTIYLEKLHVYHHFNDEHTMMLLSCYKKQCKKKKMISFIKKNKDKINLNKTYKFLLNAGYYNIVLNLSKKYKDHFTYVSILIEKYENYEKSLKYIFKLDVENICILLFKYGYKFIKYYPQLTIYLLKKIIKKYNINLTIFIPLFLDNIDFLFMFIVKFLDKNVNINKINHIQEKQKHHYSNMYHDSDELNSVTKQKNKINSFLLYEKDNNQNHNGIPSDSHNLSDDNNSQESTTAVNLINKTNLQLDIFNGEYDYILFVTVIQILLQKYKKSMQEENQTNNQSSKQTNNQSSKQTNKQSINQSNNQSINQTNNQSIKQTNIQTNKQKGNSTTNKIINKDETNEQNNILTFNIDKLIQNNKDKNINFLSVLLLSIYNYNKGLIYTSTQMNKYDISLLFSIHKFINNTKGKINKINMDEHKPNEQTMQINSSYKILNRNFQKVIYNICINHLKLNGSLSYNYIFYYLSMLNDEKYLIKFIKKIRQDMNLSIFNLIQILKKYNKSYSCIQNMVVAYMNDMNKNINDKCIEIEKDKKELEKIKKKQLKKKYNFYLIDNAYCSICKEILSVPMIHFLCKHSYHSYCLKDNNVCILCHNKDKEKKLLKEKAINSIQNFDEFFKYLQGSTDKFSYISNYLSYGITPK
What are the official names of this protein?
RING finger protein PFE0100w.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EFP_PROMT
Sequence: MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGNVVEKTFRAGEMVPQALLEKSKLQHTYMDGDDFVFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKPLEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQVMVPLFISIGEKIRVDTRNDSYLGRETQ
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_ECO24
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: MSI1H_RAT
Sequence: METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
What is the function of this protein?
RNA binding protein that regulates the expression of target mRNAs at the translation level.  Regulates expression of the NOTCH1 antagonist NUMB.  Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'.  May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
What are the official names of this protein?
RNA-binding protein Musashi homolog 1, Musashi-1.
What is the protein family that this protein belongs to?
Belongs to the Musashi family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAX_I73A4
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFINELGESVIIESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTRAEKPKFLPDLYDYKENRFVEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQGQCAGLPITVSHRTSPALKILEPMWMDSNRTAALRASFLKCQKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: DHA2_STAAS
Sequence: MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: ERIC2_RAT
Sequence: MDTDFPVSLSPAFLKVTRVRGQACPRVCAPNLPRSVTPSTSGRWATRAARSALHVVPAAGTAPAPPPPRALRPAPGPPRSAPLAPPLRRVVQSLGSSRGSRASCCSPSCLHGDSASQARGSEPSSSAERGWPSWSGLRGNSLAGRPEGWASGTPRLSKHPQRSLVPEFCIPEIPSNYLDKTEVVKAPKSRQNGRLLLCDPKEKLMSGSNKEKPQKSSFGRRPRLSSKLCTSPTQIPGGATVFSARKETSSKKIEDKVSLKSSENRPSSRSIETNRQFDLWSSSFLKESSGEVNKDLVLAKQEKNSEYCLEDIEENLSDSTDGDGEEDSNNEDDEGPAKKETRAPLELMAEFLRAEMGRDYQLAKKLCQMILIYEPENPVAKEFFSLIEEILLKEKAQEEEEEEESDEDSSSESEVDSSEDGSEDSSDECEDGS
What are the official names of this protein?
Glutamate-rich protein 2.
Protein: SENP8_HUMAN
Sequence: MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
What is the function of this protein?
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
What are the official names of this protein?
Sentrin-specific protease 8, Deneddylase-1, NEDD8-specific protease 1, Protease, cysteine 2, Sentrin/SUMO-specific protease SENP8.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
Protein: RL11_TREPS
Sequence: MAAKKKVVTQIKLQCPAGKATPAPPVGPALGPHGVSAPQFVQQFNDRTKSMEPGLVVPVVVTVYSDKSFSFVLKTPPAAVLIRKACGIEKGSTNSVKQKVARLSLAQLTEIAQVKLPDMSALTLDAAKRIIAGTARSMGVEVERSL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y5282_PSEPG
Sequence: MRVWIDADACPKAARDLIVKFALKRKFEVVMVAGQAVAKPAFAIVRLIVVPSGMDAADDYLVEHAVPGELVICSDVPLADRLVKKGVAALDPRGREFDERNMGDRLAARNLFTELREQGQVGGGQGAYGEREKQAFANALDRIIARLSKS
What are the official names of this protein?
UPF0178 protein PputGB1_5282.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RBX1_MOUSE
Sequence: MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
What is the function of this protein?
E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair (PubMed:22118460, PubMed:33590678).  CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (By similarity).  The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components (By similarity).  As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation (By similarity).  Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate (By similarity).  Probably also stimulates CDC34 autoubiquitination (By similarity).  May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair (By similarity).  Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M (By similarity).  Involved in the ubiquitination of KEAP1, ENC1 and KLHL41 (By similarity).  In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM (By similarity).  As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein transferase RBX1, RING finger protein 75, RING-box protein 1, Rbx1.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARAF_HUMAN
Sequence: MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
What is the function of this protein?
Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.
What are the official names of this protein?
Serine/threonine-protein kinase A-Raf, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1, Proto-oncogene Pks.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: NHAA2_CLAM3
Sequence: MTSLIRSERVAAGLLLLAAVVGLVVANTPAGPGLLAWADGHLALPAIGVDLSLRHWVSDGLLVVFFFIVAVELKHEFLAGGLNSVSRALVPAIAAVGGVVVPALVYLAITAGSGLERGWPVPTATDIAFALGVLAVFGRGLPAAVRVFLLALAVLDDLIAIGIIAVFFTTGLDLGALAIAVAGVVLFAVVGRLGVGRTGAARIAVVALLVLVALVTWWATLSSGIHATIAGVALGFALPRLSGLRAAHALEPASNGIVLPLFAFSAALVAIPAIGLAELAPAFWGIALALPLGKLVGITAGGLLGAWVARRRGSAGGLAVPDLVTVSLLGGIGFTVSLLMSELAFAGLDDVRDEGTLAVLLGSGVAIVAAAVTLSIRSRRARRAGAAADDDDATRDDFPAHADGGPARA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NOP2B_ARATH
Sequence: MAALTRNKKKGSNSQTPPLNKQTKASPLKKAAKTQKPPLKKQRKCISEKKPLKKPEVSTDEEEEEEENEQSDEGSESGSDLFSDGDEEGNNDSDDDDDDDDDDDDDDEDAEPLAEDFLDGSDNEEVTMGSDLDSDSGGSKLERKSRAIDRKRKKEVQDADDEFKMNIKEKPDEFQLPTQKELEEEARRPPDLPSLQMRIREIVRILSNFKDLKPKGDKHERNDYVGQLKADLSSYYGYNEFLIGTLIEMFPVVELMELIEAFEKKRPTSIRTNTLKTRRRDLADILLNRGVNLDPLSKWSKVGLIVYDSQVPIGATPEYLAGFYMLQSASSFLPVMALAPREKERVVDMAAAPGGKTTYVAALMKNTGIIYANEMKVPRLKSLSANLHRMGVTNTIVCNYDGRELTKVLGQSSVDRVLLDAPCSGTGVISKDESVKTSKSADDIKKFAHLQKQLILGAIDLVDANSKTGGYIVYSTCSVMIPENEAVIDYALKNRDVKLVPCGLDFGRPGFSSFREHRFHPSLEKTRRFYPHVHNMDGFFVAKLKKMSNAMQPSGNDEPAVTMEQAQVSSSDDDDEKAEAIEELEKPPVASGQPKRESNTKEDTNKRKNPRSKEIHKGKRNKNTKTESGNVEEPRKQKKKRSQWKNEIAQAREEKRKTMRENAKETPKHRG
What is the function of this protein?
Involved in ribosomal large subunit assembly (By similarity).  S-adenosyl-L-methionine-dependent methyltransferase that probably methylates the C(5) position of cytosine 1586 (m5C1586) in mitochondrial 26S rRNA (PubMed:26268215).  May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (By similarity).  Seems involved in the regulation of cell proliferation (By similarity).
What are the official names of this protein?
26S rRNA (cytosine-C(5))-methyltransferase NOP2B, Nucleolar protein 2B, tRNA methyltransferase 4d, AtTRM4d.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: NADK_XANC8
Sequence: MTAMPRIAFLASPAEPAVAARARLVQRYGDHALHDADIVCALGGDGFMLQTLHRHGAADKPVFGMKLGSVGFLMNQYRDDEDDLLARLQRAEPAHLRPLEMLVQTESGTSAGSLAYNEVSLLRQTRQAAHLSVDLNGQTRIAELIGDGVMVATPAGSTAYNYSAHGPILPLGSHTLALTPIAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHEIRDVVEVTIRESTERRVTLLFDPEHNLEERIFSEQFAV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_STAA3
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PERC1_MOUSE
Sequence: MAAGVIRSVCDFRLPLPSHESFLPIDLEAPEISEEEEEEEEEEEEEEEEEEVDQDQQGEGSQGCGPDSQSSGVVPQDPSSPETPMQLLRFSELISGDIQRYFGRKDTGQDPDAQDIYADSQPASCSARDLYYADLVCLAQDGPPEDEEAAEFRMHLPGGPEGQVHRLGHRGDRVPPLGPLAELFDYGLRQFSRPRISACRRLRLERKYSHITPMTQRKLPPSFWKEPVPNPLGLLHVGTPDFSDLLASWSAEGGSELQSGGTQGLEGTQLAEV
What is the function of this protein?
Plays a critical role in intestinal function by promoting the development of enteroendocrine cells (EECs) of the gastrointestinal tract and pancreas (PubMed:31217582).  It is thereby required for normal enteroendocrine peptide hormone secretion (PubMed:31217582).
What are the official names of this protein?
Protein PERCC1, Proline and glutamage-rich protein with a coiled coil domain.
Protein: RL7_GEOMG
Sequence: MAEITKADVVSFIENMTVLELSELVKELEEKFGVSAAAPVAVAAAAAPAAAAEAAEEKTEFDIILKSAGANKIGVIKVVRALTGLGLKEAKDLVDGAPKSVKTGVSKEEAEDAKKQLVESGAEVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MTFR1_PONAB
Sequence: MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISLPDFSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPLPPPPPPPPPPLGLHQSISAVDLIKERREKRANAGKTLVKNSPKKPEMPNMLEILKDMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGVPKSESEATSERVLFGPHMLKPTGKMKALIENVSDS
What is the function of this protein?
May play a role in mitochondrial aerobic respiration.  May also regulate mitochondrial organization and fission (By similarity).
What are the official names of this protein?
Mitochondrial fission regulator 1.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=May be associated with the inner and the outer mitochondrial membrane.
Protein: TSAD_MANHA
Sequence: MRILGIETSCDETGVAIYDEDKGLVANQLYSQIDMHADYGGVVPELASRDHIRKTLPLIQEALKEANLQPSDIDGIAYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHLLAPMLEENAPEFPFVALLISGGHTQLVKVDGVGQYELLGESIDDAAGEAFDKTGKLLGLDYPAGVAMSKLAESGTPNRFKFPRPMTDRPGLDFSFSGLKTFAANTIKANLNENGELDEQTKCDIAHAFQQAVVDTILIKCKRALEQTGYKRLVMAGGVSANKQLRADLAEMMKKLKGEVFYPRPQFCTDNGAMIAYTGFLRLKTMNKPT
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Not secreted through the conventional secretory pathway since it lacks a signal sequence.
Protein: YL125_YEAST
Sequence: MGEILELTNKNFMSHLKKDITSQESLKSRIEDKNGDVASPKEDNYPLLNETAAWPDGVITSEEGCSSSGEKENSGLCSEESSEEDPEEAEEESARAFGELVAVLRDKDIPLNVLDEPQMKDWLEKYTGVYRSSWHG
What are the official names of this protein?
Putative uncharacterized protein YLR125W.
Protein: PSA7_SOLLC
Sequence: MARYDRAITVFSPDGHLFQVEYAMEAVRKGNAAVGVRGTDTVVLGVEKKSTPKLQDSRSVRKIVNLDDHIALACAGLKADARVLVNKARIECQSHRLTVEDPVTVEYITRYIAGLQQKYTQSGGVRPFGLSTLIIGFDPHTGVPSLYQTDPSGTFSAWKANATGRNSNSTREFLEKNYKETSGQETVKLAIRALLEVVESGGKNIEVAVMTKEHGLKQLEEAEIDAIVAEIEAEKAAAEAAKRPHRRNLVELKFVLNYP
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7, 20S proteasome alpha subunit D, 20S proteasome subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LEXA_PAEAT
Sequence: MAAKATGGGAPLRSQQPQKSPKSLTVRQKKILETIQRSVNDNGYPPSMREIGDTVGLASLSSVTHQLSQLEKLGYLRRDPKRPRAMEVLMPLTLDGGAIPGVEAPTTLRSAGGLAVTELASASDTAMVPLVGRIAAGGPILADQTVEDVLALPRQLVGHGELFMLKVAGDSMIDAAICDGDWVVVRRQNDAINGDIVAALLDDEATVKTFRQRDGHTWLLPQNTQYEPILGDQATIMGKVVSVLRSL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: FGD_MYCS2
Sequence: MAELKLGYKASAEQFAPRELVELAVLAESAGMDSATVSDHFQPWRHEGGHAPFSLAWMTAVGERTKNLVLGTSVLTPTFRYNPAVIAQAFATMGCLYPGRIFLGVGTGEALNEIATGYAGEWPEFKERFARLRESVRLMRELWLGDRVDFDGEYYRTKGASIYDVPEGGIPVYIAAGGPVVAKYAGRAGDGFICTSGKGEELYAEKLIPAVKEGAAAADRDADAIDRMIEIKISYDTDPELALENTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVEKVGQYVKWGLNHLVFHAPGHDQRRFLELFKRDLEPRLRKLA
What is the function of this protein?
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.  Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.  Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor.  Exhibits nearly no activity with D-mannose-6-phosphate or D-fructose-6-phosphate as substrate.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: TRPB_CLOK5
Sequence: MNKSYENSGRFGRFGGQYVPETVMTALMELEESFNKAKEDSKFIDEYMYYLQEYSGRPTPLYYAENLTKNLGGAKIYLKREDLNHTGAHKINNVLGQILLAKRMGKKKVIAETGAGQHGVAVATGAAMFQMECVIYMGEEDCRRQSLNVLRMKILGAKVVSVESGTKTLKDAVNEALRKWVENIEDTFYVMGSVVGPHPYPTMVRDFQRIIGDETKEQILKKEGKLPNYIIACVGGGSNSMGIFYPFVEDKSVKLIGVEAAGLGVDTDKHAASMAKGSVGVLHGMMTYLIQDDEGQILPVYSVSAGLDYPGVGPEHAYLKDTKRAEYTYVTDQEALDAFGYLSRCEGIIPALESSHALAYTMKLAPELSKEEIVVVNISGRGDKDVDTISELNIFG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SOR_PYRHO
Sequence: MLKETIRSGDWKGEKHVPVIEYEREGDLVKVEVSVGKEIPHPNTPEHHIAWIELYFHPEGGQFPILVGRVEFTNHSDPLTEPRAVFFFKTSKKGKLYALSYCNIHGLWENEVQLE
What is the function of this protein?
Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
What are the official names of this protein?
Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.