PharMolix/UniProtQA huggingface dataset:
Protein: FLPA_PYRAE
Sequence: MSIEVVEVKPHERHYGVYVVKFEDGTERIATKNLTPGRRVYGERLIKWGGDEYREWNPYRSKLAAAILNGLKLVPIKEGTHILYLGAASGTTPSHISDIVGENGLIYSVEFSPRVFREFMEKLVDQGRRNVVPILGDARFPYQYAHYVKGVDVVYIDVAQPAQAKILADNADYFLKPGGHVMLVIKAMSIDVTAPATETFKQEINTLKERGFDILETVHLEPYDTAHAMVIAKKR
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: NTPPB_VIBCH
Sequence: MQNYQLVLASTSPFRQQILAKLKLPFVTAKPDCDETPLIGETPEHLLMRLAENKARSCFLADPSLVIGSDQVCVIDDQIIGKPLTTEKAVEQLLRQSGQAITFYTGLALFNNQTQQTQVLCDTFTVHFRTLSESMARRYVEAEQPLHCAGSFKSEGLGIALFERLEGDDPNSLIGLPLIKLIQLLENEGLNVI
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_DESHD
Sequence: MAQASQCIRNFSIIAHIDHGKSTLADRLIEYTGALSKREMEAQVLDNMDLERERGITIKLQTVRLQYPAKDGQTYELNLIDTPGHVDFTYEVSRSLAACEGALLIVDAAQGIEAQTLANVYLALENNLEIIPVINKIDLPSAEPERVKQEIEDVIGLDASEAILASAKTGIGIEDILEAVVAKVPPPQGDDNTPLKALIFDSYFDAYKGAISYVRVMEGRVAKGTQIKMMSSGKVFDVTEVGMFTPALRIVDEIKAGQVGYIAASIKNVRDTQVGDTITDAENAALYPLPGYRKATPMVFCGLYPVDSSDYGRLKDALEKLHLNDSSLVFEPETSSALGFGYRCGFLGLLHMDVIQERLEREYDLNLITTAPSVVYKVNKTDGEVLSIDNPSNLPKVDEIETIEEPIVKANIMVPSDFVGAIMELNQEKRGNFLNMDYLSANRVTLHYELPLSEIVYDYFDQLKSRTKGYASLDYELAGYKAASLVKLDVLLNGELVDALSFIVHKEKSYARGRRLVEKLRGIIPRQMFEVPIQAVIGQKVVARETVKAMRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGSVEIPQDAFMAVLKIDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MINE_BURM7
Sequence: MSILSFLLGEKKKSAAVAKERLQLIIAHERVGGRPPADYLPALQKELVAVISKYVKISNDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: END3_ASPOR
Sequence: MSNKKIEQWEIERYWEIFASLANGQPRLNNSQAASVLRNSRLRDEQLEKVWDLADVDGDGELDFEEFCVAMRLVFDLVNGELQTVPAVLPDWLVPESKSHLVHATRALSTQPEQFERIEDEDDTPGLKDGFEWYMKPADKSKYEEIYNANRNQRGEIAFESLQPLYDSLDVPDTDVRSAWNLVNPSASHTINKDATLAFLHILNYRHEGFRIPRTVPASLRASFENNKIDYQVDNARPAQKWGADGDTETPTGRKTKFGDTYLSRLGAGGKSSYTPKGTNFSDTIQDEEWEKVRLRRELAELETKLNSAQQASEGRRDQPRNDGRTSWGLVKKEALQLLEYKERELRELREGTGRSKEGQNLERLREDVKAVGEQVDGLKSHLANRNEVLADLRRQIDEEKVSR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein end3, Cytoskeletal adapter protein sagA, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: TLCD5_DANRE
Sequence: MPLFIVETSCSLISWLFLYLLLCHLNSGRDSEWNCRLVTLFHGILIICLTAYIGFIAGPWPFTHPGTENTYFQILTLVLSLGYFLFDMAWCVYFRTEGPVMLAHHTMSIFGILLALGLGESGIETCAVLFGSEITNPLLQARWFLKRMGCYDSLAGDVVDLLFILLFASVRIGVGSRMLYCELTSPKPSLIVKVGGVAIYTLSWIFMVDIARFACRKTCGKYRRWKEQYKLDGVNGHAVKIK
What are the official names of this protein?
TLC domain-containing protein 5, Transmembrane protein 136.
What is the protein family that this protein belongs to?
Belongs to the TLCD5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPE_BREBN
Sequence: MSKMTVEVVTPERVVYSGQAEMVIARGLQGEIGIMPNHMPLVTPLKTAPVRIKTEGDKEVKMAVSGGFMEVRGDKVTILAETAELPGDIDVERAKAARERAEKRLTEKYAELDVKRAERALQRAMARLDVSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CD151_CHLAE
Sequence: MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGAVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGVLAYVYYQQLNTELKENLKDTMAKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRLREARGRVVPDSCCKTVVAGCGQRDHAFNIYKVEGGFITKLETFIQEHLRVIGAVGTGIACVQVFGMIFTCCLYRSLKLEHY
What is the function of this protein?
Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
What are the official names of this protein?
CD151 antigen, Platelet-endothelial tetraspan antigen 3, PETA-3.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFKA_THET2
Sequence: MKRIGVFTSGGDAPGMNAAIRAVVRQAHALGVEVIGIRRGYAGMIQGEMVPLGVRDVANIIQRGGTILLTARSQEFLTEEGRAKAYAKLQAAGIEGLVAIGGDGTFRGALCLVEEHGMPVVGVPGTIDNDLYGTDYTIGFDTAVNTALEAIDRIRDTAASHERVFFIEVMGRHAGFIALDVGLAGGAEVIAVPEEPVDPKAVAEVLEASQRRGKKSSIVVVAEGAYPGGAAGLLAAIREHLQVEARVTVLGHIQRGGSPTAKDRILASRLGAAAVEALVGGASGVMVGEVEGEVDLTPLKEAVERRKDINRALLRLSQVLAL
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_CLOAB
Sequence: MQVSIEDIIENLDLEVLVKGKDGIKLGLSDINRPGLQFAGFYDYFGNERVQVIGKAEWSFLNAMPPEIREKRIRKYFQFETPCIVLARGLKPQKELLDCSKEYNRWLLRSKAQTTRFINKIMNYLDDKLAPETRIHGVLVDIYGLGILITGESGIGKSETALELIKRGHRLVADDAVDIKEIESVLVGKSPYITSGMLEVRGMGIIDVPALYGLSSVLSEKNINLVIYLEQWKEGRDYDRLGTDDEHIKILNIPVRKMTLPIRPGRNVAVIIEAAAANYRYNLSSKISPVDTINKRIEESTNYD
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CH10_HELPS
Sequence: MKFQPLGERVLVERLEEENKTSSGIIIPDNAKEKPLMGVVKVVSHKISEGCKCVKEGDVIAFGKYKGAEIVLDGVEYMVLELEDILGIVSSGSCCHTNSHDHKHAKEHEACCHDHKKH
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AXL1_YEAST
Sequence: MSLREVTNYEVSFYIPLSYSNRTHKVCKLPNGILALIISDPTDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAGSKKYPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESILDVFASFFKEPLFNPLLISKEIYAIQSEHEGNISSTTKIFYHAARILANPDHPFSRFSTGNIHSLSSIPQLKKIKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSAVKERSISIRTRSFRRSKSLKKRQDSSKNDYSDLKTFKILNTTWEKKYKNTMCFQQFPECNSIFINSNKVPIMRLLFPVSDKNTRFTKDDIKIYSHLWCELFGDESPGSLSYYLASKGWLTGCFAFTSEFAIGDIGLILELELTNSGWENIKRITTIVLNRLLPSFYVMNIDYLITFLKEQNLIDLVSFLYQSSEDLPMEECSKLSGILQDDLECLTPPNIFKGFKSLIEIDDPNIEKYENTKANIQWWTGQAIKFQNFLKSFMNHDNMRLLLLGNIKSGNIFDKMKNKSDICTDFFYEFEYYTANVHLASDNKFHSNSSYEFNFPTGNLFLPDCVSDPLKLQQLFLECSLKSKFATLRPQIYSEPTRTKPQLVSENQNYEMWILKEDPNFASDNKSVVSFEVLGLGIKPSPEATIHLEVLAQALFIITSSFLYPALRIGYTYEIASSSKGNVTLRFTISGFPEGVFTIVKTFVDTLKLIATDPTFLSKDTLRKARILVRNKYKNASSDNCVKLASVGLLIVLEKYIWTLEDRINALELTELESFEKFCFLFWRNPKHLVLFMQGSLEYADAINRYLNNNFTQHLKISNEGSKPTIRLYPPPSTKDLDQGTNAFISYNGHQDDPNNSIVYFIQTAQRDDIKNLTLTFLTEYLFSLTLVPDLRNKKQIGYIVLGGLRVLTDTVGIHITVMSGSSGHNLETRINEYLSYLQLQVLNRFTEFDFRRILLEPFLNLLKQNSTKQFEGSAGPVDLLNEIVANVQNGDNYTLNNKQMRQHRKVRNKIAEGRLNFQEDHEMIDISFLQKLTLKKYLAFFESKISIYSAQRSKLSIMITSPMAEKEIASRKMFLQLEAFLKINGFAIKNEDLKKIVEHSKGNPILLVKNLFTYFRRRNEVFKLGTVVLQEILKIIGMNLKQRYGSILGFSSQDGEGQEIEKFWNNDTSPIVPLQELPEPNFFRKAAF
What is the function of this protein?
Probable protease.  Involved in axial budding.
What are the official names of this protein?
Putative protease AXL1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Bud neck. Note=Mother-bud neck and division site remnants of haploid cells.
Protein: SYI_PSEPW
Sequence: MTDYKATLNLPDTAFPMKAGLPQREPQILQRWDSIGLYQKLREIGKDRPKFVLHDGPPYANGKIHIGHALNKILKDMIVRSKTLSGFDAPYVPGWDCHGLPIEHKVEVTHGKHLTADRTRELCREYAAEQIEGQKTEFIRLGVLGDWDNPYKTMNFANEAGEIRALAEMVKQGFVFKGLKPVNWCFDCGSALAEAEVEYADKKSQTIDVAFPVADADKLAAAFGLPALAKPAAIVIWTTTPWTIPANQALNIHPEFKYALVDTGERLLVLAEELVESCLKRYNLEGSVIATAQGSALELVNFRHPFYDRLSPVYLADYVELGAGTGVVHSAPAYGEDDFVTCKRYGMVNDDILTPVQSNGVYVESLEFFGGQFIWKANPAIVEKLSEVGALMHTETISHSYMHCWRHKTPLIYRATAQWFVGMDKQPSTGEPLRERALKAIEDTQFVPAWGQARLHSMIANRPDWCISRQRNWGVPIPFFLHKQTGELHPRTVELMEAVAKRVEQEGIEAWFKLDAAELLGDEAGQYDKITDTLDVWFDSGTTHWHVLRGSHDIGHATGPRADLYLEGSDQHRGWFHSSLLTGCAIDNHAPYRELLTHGFTVDESGRKMSKSLGNTIEPEKVNNTLGADILRLWVSATDYSGEMAVSEQILQRSADAYRRIRNTARFLLSNLSGFDPARDLLAPEDMLALDRWAVDRTLLLQRELEEHYSEYRFWNVYSKIHNFCVQELGGFYLDIIKDRQYTTGANSVARRSCQTALYHISEALVRWIAPILAFTADEIWQYLPGERNESVMLNGWYQGLSELPEGTELDRAYWDRVMAVKAAVNKELENQRTAKVIGGNLQAEVTLFAEEGLSADLSKLGDELRFVLITSAASVVPFAQAPADAVATEVEGLKLKVVKSGHAKCGRCWHFRADVGSHPEHPEICSRCVDNLSGSGEVRHYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCD_AGRT4
Sequence: MPIDPKLNVVPFISVDHMMKLVLKVGIDTFLTELAAEIEKDFRRWPIFDKKPRVGSHSQDGVIELMPTSDGSLYGFKYVNGHPKNTHQGRQTVTAFGVLSDVGNGYPLLLSEMTILTALRTAATSALAAKYLARPNSKTMAIIGNGAQSEFQARAFRAILGIQKLRLFDIDTSATRKCARNLTGPGFDIVECGSVAEAVEGADVITTVTADKQFATILSDNHVGPGVHINAVGGDCPGKTEISMEVLLRSDIFVEYPPQTWIEGDIQQLPRTHPVTELWQVMTGEKTGRVGDRQITMFDSVGFAIEDFSALRYVRAKITDFEMFTELDLLADPDEPRDLYGMLLRCEKKLEPTAVG
What is the function of this protein?
Catalyzes the conversion of L-ornithine into L-proline with release of ammonia.  Is involved in the utilization of octopine, a catabolic pathway that proceeds through L-arginine and L-ornithine to L-proline.  Octopine is a predominant opine in plant cells transformed with Ti plasmid pTiAch5.
What are the official names of this protein?
Ornithine cyclodeaminase, OCD.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: DHQS_NATPD
Sequence: MTRSVWLKADDAVGDWEARKRRITAGLEAGVDWVLVDERDVSRVRELGQVNVAAFAGDDVHVMDAEEQPDAEPDAVIVGKEGEGDGTVDLPSDFSGSADLTTLRRAEAPAGAYVRILDQDYESFAETAAVDADYTIVIGDDWQIIPLENLIARIGDETDLIAGVQTAEEAETAFETLELGADAVLLDTDNPDEIRATVEARDATERETLDLQRATVTEIEETGSADRVCVDTASMLEHDEGMLVGSMSRGLFFVHAETADSPYVASRPFRVNAGAVHAYVRTPDGGTKYLAELSSGDEVQVVDTDGNTREAIVGRAKIEKRPMFRIEAELENGDRIETLLQNAETIKVATDEGRRSVTELEAGDELLIYYEDVARHFGEAVEESIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: NEP_I76A0
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEMRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: Y090_MYCTU
Sequence: MAKNQNRIRNRWELITCGLGGHVTYAPDDAALAARLRASTGLGEVWRCLRCGDFALGGPQGRGAPEDAPLIMRGKALRQAIIIRALGVERLVRALVLALAAWAVWEFRGARGAIQATLDRDLPVLRAAGFKVDQMTVIHALEKALAAKPSTLALITGMLAAYAVLQAVEGVGLWLLKRWGEYFAVVATSIFLPLEVHDLAKGITTTRVVTFSINVAAVVYLLISKRLFGVRGGRKAYDVERRGEQLLDLERAAMLT
What are the official names of this protein?
Uncharacterized protein Rv0090.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZC12D_MOUSE
Sequence: MEHRSKMEFFQKLGYSQEDVVRVLGKLGDSALVNDVLQELIQTGSRPRAQEDPASGTGVVLIPRGCCGVQDSAQQGPGTRPRRGWRRSSPLLRPIVIDGSNVAMSHGNKEAFSCRGIRLAVDWFTDRGHTYIKVFVPSWRKEPSRSDTPIREQHVLEELERQAVLVYTPSRKVNGKRVVCYDDRYIVKVAYEKDGIIVSNDNYRDLQNENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLSNFLSKKPRPPEPSWQHCPYGKKCTYGVKCRFYHPERPHHGQLSVADELRAKTRAWLGGGAEEPRTPSARSRPTTARLLPQEPGEHDLPPAPQPAVLAALNRSFARLTFSDTAASGVVSQSRGPDWMPTGVPTSWAPPSLRAGSAATIGLPGMRSLRTPNNPLSPGDLGSPICPQARLSERHRSRDMHSDLPPQRRPLEDPWALLPSSYCYLNHSVWSESAWGEDIFRGPSESAQPVANGGGTRPVHCSFFPPDQDHPVMASGPPLSDMALLTLLQRSQKTGAPLGDP
What is the function of this protein?
May regulate cell growth likely by suppressing RB1 phosphorylation (By similarity).  May function as RNase and regulate the levels of target RNA species (Potential).  In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560).  Serve as a tumor suppressor in certain leukemia cells (By similarity).  Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (By similarity).
What are the official names of this protein?
Probable ribonuclease ZC3H12D, MCP-induced protein 4, Transformed follicular lymphoma homolog, Zinc finger CCCH domain-containing protein 12D.
What is the protein family that this protein belongs to?
Belongs to the ZC3H12 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Note=Colocalizes with ZC3H12A in GW bodies (GWBs).
Protein: SFSA_RUMCH
Sequence: MKYKNIKRGIFIERPNRFIAHVEIDSVTEICHVKNTGRCKELLIPGTVVYIQKSDNPKRKTGFDLISVIKGSRHINMDSQAPNKLVQEWMEKGNLFSGITLVKAESRYKNSRFDFYVETKEDKIFIEVKGVTLEENNIAMFPDAPTERGVRHIKELCDSLHDGYKAYIIFVIQMKDVDYFIPNETTHREFSDALKSAYRKGVNILALDCVVEEGFIEIEKQVEVRL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: STPS3_SALMI
Sequence: MATTQVEIQRPIANFSPSLWGDQFIKNDSGAKAAEKHCKAVEELKKEVMNMITAAESNLVEAMNLIDTLERLGISYHFEKEIDQKLNHFFSLNTDYSDESYDLYTVSLHFRLFRQHGHRISSDIFGRWIDESGKFKEGLKTDGKGLLSLYEASYLRTRGETILDDALEFATATLNSIAPHLESPLSKQVVHALIQPLHYGNPRIEAHNFISIYEENQDKNEFLLKFAKLDYNLLQMLHKEELHEVSRWWKELDLVSKLPYARDRVVECFFWAMGVYHEPQYSRARIMLTKTITMTSIIDDTYDAYGVIEELDIFTEAIERWNIEEMDRLPEYVKPFYKALLELYEQFEEELAEEGRSYAAHYAIESLKELVRSYHVEAKWFIQGYLPPFEEYLKNALITCTYCYHTTTSLLGVESAVEEDFQWLAKKPKMLVAGLLICRVIDDIATYEVEKERGQSATGIESYMRDNNATIEEAVAKFFEIATDAWKDINEECLMPSPYSRDVLMRILNLERIIDVTYKGNEDGYTQPEKVLKPHIIALFVDPIKM
What is the function of this protein?
Sesquiterpene synthase that catalyzes the conversion of farnesyl diphosphate to (-)-5-epi-eremophilene.
What are the official names of this protein?
(-)-5-epieremophilene synthase STPS3, Sesquiterpene synthase 3, SmSTPS3.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: MOC2A_ARATH
Sequence: MDKEVTKIESDDTSSVEIKVLLFARARELTGVPDLTLKMPSGSTTQKCLDELVLKFPSLEEVRSCVVLALNEEYTTDSAIVQHRDELAIIPPISGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STAAE
Sequence: MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSDFEQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQTKEDVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_SHEB2
Sequence: MSEGESKSTHFGYKTVEVDKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSGARPGMKVLDLAGGTGDLTAKFSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVLKPGGKLLVLEFSKPQHEIMRKVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTDGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: 241L_IIV6
Sequence: MELKLTDLAFTALPNGKVLPPGILSSSSNCKKCGLRCDNGLPYCFNCQFKCQVCGSYDNLLIKNNSTETLCKYVNPKDHVYKFATNRSAYKMKYKLCSKCKDYVLCAMCLTFNQNAFAKEIWSYEEPLFVMEICKKCMHKHTCDECNTPSSSNIKIFLDGYIYCNKCDEE
What are the official names of this protein?
Cysteine-rich uncharacterized protein 241L.