PharMolix/UniProtQA huggingface dataset:
Protein: METK_PARD8
Sequence: MSYLFTSESVSEGHPDKVADQISDALLDEFLAYDKNSKVACETLVTTGQVVLAGEVKSSAYVDVQEVARGVIEKIGYTKSEYQFEAKSCGVFSSIHEQSGDINRGVERADPYEQGAGDQGMMFGYATNETENYMPLALDLSHSLLWELAKIRKEEPDLMPYLRPDAKSQVTIEYDDNGKPLRIDTIVVSTQHDEFIGPKGISQKEADEAMQKRIALDVKKILIPRVKAQYPAHVQALFNDNIIYHVNPTGKFVIGGPHGDTGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAYAARHIAKNMVAAGVADEMLVQVSYAIGVAKPMNIFVNTFGRAKVNMTDGEIAAKIWDIFDMRPKAIEERLKLRNPIYFETASYGHMGRKPQTVTKTFSSRYLQKPVTCDVELFTWEKLDYADKIKDVFGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_CUSEX
Sequence: MFTLKLFVYTVVIFFVSLFIFGFLSNDPRRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: FMT_CHLMU
Sequence: MLNLRVVYLGTPQFAATVLETLVDARIHVVGVVTRADKPQKRSSKPIASPVKQLALSKNIPLLQPTKTTDPAFLAQLREWQADVFVVVAYGVILKQELLDIPKYGCYNLHAGLLPAYRGAAPIQRCIIAGETLSGNTVIRMDAGMDTGDIANVNHVAIGEDMTAGELAEALAGSGGELILKTLQEIEAGTVRHIPQDSAKATLAPKLTKEEGLVKWDAPASQVYAHIRGVSPAPGAWTRFLSQGKEPRRLGILSARMESSSGSHSPGEVLGVSGEDLLVACRQGVLRLCIVQPEGKVFMKAKDFFNGQSRSVALLF
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: I2BC_CONEP
Sequence: MMFRVTSVGCFLLVILSLNLVVLTNACLSEGSPCSMSGSCCHKSCCRSTCTFPCLIPGKRAKLREFFRQR
What are the official names of this protein?
Conotoxin Ep11.12.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEAT9_HUMAN
Sequence: MAYEKSTDISDVSRSMFLYPWLEYPDKTKELRKAMAPVHLPLSCYQMPKEEFPPSPECWRQHPSKPNSVPYCYFKKPEIYTHWHDLYDQREEREAEKMLRKMRDDCRYIKEVHQTHIKMFHLPMSKLTIKSEMRSRPLEPTQDPLKWQRLRELTKSLESPREDEQFYAAQALGCLRISDKFVMEALQQVAQTGPEKVKYEAYRTLAILGCLNKHVIRALIKQLKEKNEGQRMETLTGLRMALNSWAAVSKDKRTQVGDEGKLVPVLQTLIKKSSSEASLEAALCLGFLRPCSNMVQEFLLQCLCQGLKTQRMKALRMLVKVMHVHSAPVIKAILDQLCSSSVLEDRFEATQMLKTIGLEQIQAQGLEELTFNLLRRKTHNEPFLAVRQAVAQTVEELKLKPTMMNLVEAQLMNPDATARQEAVISLGVLGIRSPQVFHLLLDLLDAENHQAVKKSLQETLILCASIDPWIQNKLKNKVLSVYEAPKTNVKAEPTRFQKEPENPEELTIQDFRLAKLNPLFIAKSITKVGQKKTPAFPPCCSKPRKHRPQVIGPWQPRIKKQLRVLAEIAK
What are the official names of this protein?
Protein HEATR9, HEAT repeat-containing protein 9.
Protein: RF2_NEOSM
Sequence: MDFETQVVLHNLKKSVEVIRRQLDIEKKHSRLEEIQALVDSPTLWEDQSRAQLLLKEKSQIETSLKEFKELSIQLDDLIEMIELASKDHEEETMKDLERELLLLKEKIQKKEIECLFSGEADGNDCLLEIQSGAGGTESNDWAMMLLRMYTRWAEIYHKFQVQIVDKVEGEETGIKSCTLKVMGKNAYGWARTETGVHRLVRISPFDANAKRHTSFAKIFVSPCIEGEINISIDEKDLKIDTYRASGAGGQHVNKTESAIRITHLPSKIVVQSQSSRSQHQNKAEAMQMLKSRLYEIELRKKEEKLNAARNVEDSIGWGYQIRSYVLHPYQMIKDLRTGHEVGNITSVLDGDLDSFIIATISNNS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_RICBR
Sequence: MGKVIGIDLGTTNSCVAVMEGKEPKVIENSEGERTTPSIIAFANGEKLVGQSAKRQAVTNPRNTVYAVKRLIGRNFTDPMVKKDQEIVPYNIVKADNGDAWVEVEGKKHSPSQISAFILQKMKETAENYLGEKVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGFDKSASKTIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDTRILEHLINTFKKESGIDLRNDPLALQRLKEAAEKAKKELSSALTTDINLPYITADNSGPKHLNIKFTRAELEKLVDDLIEKTIEPCRKALKDAGLKASDIQEVVLVGGMTRMPKVQEAVEKFFGRALHKGVNPDEVVALGAAIQGGVLNKEVTDILLLDVTPLSLGIETLGGVFTRLIDRNTTIPSKKSQVFSTADDNQHAVTIRVFQGEREMAKDNKMLGQFNLEGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKASGKEQRVTIQASGGLSDAEIEQMVKDAEKNADEDKKHKELIEAKNAADSLIYSTEKTLTDYSDKLSSEDKGGVEEALSALKAVLDSEDASLIKEKTESLTAASMKIGEAMYKAQSDAGAAGSASEENTTSNEKVVDADFEDVEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DCUP_PSYWF
Sequence: MSIMNSDSVENTHNFAPLKNDRLLKALRFEPIDTTPVWMMRQAGRYLPEYKATRAEAGDFMSLCKDTARATEVTMQPLRRYELDAAILFSDILTIPDAMGLGLYFETGEGPKFKRTLRTEADFNQLEAFNAADSLSYVMDAVTSIRKELNGKVPLFGFSGSAWTLATYMIEGGSSKDYRYTKGLLYSKPEFLHQILDHITTAIIDYLDAQIVAGAQIVQLFDSWGGALAHRQFAEFSHKYNKRVVAELKQRHPEVPVVVFTKGGGLWLDVQMDSEADCLGLDWSMPLDKARAILATGKRKIAVQGNLDPATLYGSPELIRQSVNAMLDDAYAGGEKTGYIANLGHGITQWVDPKNAGVFVDAVHEYKL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RENR_DROME
Sequence: MLRVFVIFSLFIAAINASGEFTVLNRPKAISFKGNDALESHYVGDVLYASMGNAVSGDTNWNGLTINDPFNLAKGVILVHVQGIGHVTTAGNVKTYELTGSGTDASLNALAAELEAANEPVCDINFEQFDDGVQAWKSCFGDFEAPAAKPTKHLNPSLHTADKQFLQEVGFINSAADHLAEMAKPSNVLMLRVSVDGVAKAHGEKSVAVEEANKLLSAAISRLLAASQKSSDSVLFVQTTEKDVAASRAKRDTIAASTTNPYNLAVYYGSDYPVIFNIILWFMVVFGLSLLAICYAIAAMDPGRDSIIYRMTSTRIKKDN
What is the function of this protein?
Stabilizes asymmetric Planar Cell Polarity (PCP) domains through its interaction with stan.
What are the official names of this protein?
ATPase H(+)-transporting accessory protein 2, Renin homolog receptor, dPRR.
What are the subcellular locations of this protein?
[ATPase H(+)-transporting accessory protein 2]: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Vesicle. Apical cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Co-localizes at the apical junctions with stan. SUBCELLULAR LOCATION: [ATPase H(+)-transporting accessory protein 2 N- terminal fragment]: Secreted. Note=Localization to the planar cell polarity domains depends by stan.
Protein: TRPE_BUCBP
Sequence: MKKNLISIDVFLTETRYQPNPTAIFNQICKKKSETLLLESAEINKKHHLESMMIIDAALKISFLNQIVIVEALTKNGVNLLSVFKSLLPKNVIILSDNNPLEIKFPILSMYLDEDQRLRSLSVFDAIRFLIKSVKNLSEFAPKSMFFGGLFSYDLITSFENLPILNTHQHCPDFCFYLSETLLILDHKNKTSIVQVTSFTNDNFEKKRLKDRLEILKNKLSKNLCPIKFDTLKNMKLWCNKTDEEYNKIIVNVKKFILQGEIFQVVPSRKFYLSCVNPLSSYEVLKKNNPSPYMFFMQDRKFTLFGASPESALKYDINSRQIEIYPIAGTRPRGRRSDGSLDLDLDNRIELEMRTNNKELAEHLMLVDLARNDLAKICEPGTRHVADLIRVDRYSHVMHLVSRVIGKLRFDLDFLHAYQACMNMGTLTGAPKVRAMELISEIEGEKRGSYGGAIGYFTGLGMLDTCIVIRSAYVENKIATIQAGAGIVLDSVPQLESDESKNKAKAVIQAIANSHSCQIEYL
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: NL16_NAELO
Sequence: MITVPHVVNLNLTGQWRENGGQI
What are the official names of this protein?
Unknown protein NLV016 from 2D-PAGE.
Protein: GRPE_STRP6
Sequence: MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETPEKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDEHPADSIAEVFQKGYKLHERLLRPAMVVVYN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding (By similarity).
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_SHEB8
Sequence: MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQSLDGVDVAYFRELFSGVATKKTQLDELIIPHLERPIDEVSPVEKAIVRLATYELTFRKDVPYKVAINEAIELAKAFGADESHKFVNGLLDKLVARK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y046_PSEA6
Sequence: MKITQWPAHERPREKLLTQGPDALSDAELLAIFLRTGIKGLSAVDLARNLLNTFGSLRGLISASQQDFCLAKGLGEAKFVQLQASIELSQRFFAEQLQRETVFNSAQQTKHFLIAQLRDEPNEVFGMLLLDSQHQLIKFRKMFFGTIDSASVYPRVLVKQALEDNAAAVILTHNHPSGVAEPSQADEHITARIISAMSLLDIKVLDHLVVGDGVAVSFAERGLI
What are the official names of this protein?
UPF0758 protein Patl_0046.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RS3_YERPS
Sequence: MGQKVHPNGIRLGIVKAWNSTWYANTKEFADNLDSDFKVRQFLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PNP_HALHL
Sequence: MSESQLSLTPVKRSFQFGQHQVTLETGGVARQADGAVLVDMADTVVLVTVVGRKDPAAARDFLPLTVNYQERTYAAGRIPGGFFKREGRPSEKETLTCRLIDRPIRPLFPEGFRQEVQVIATVLSLNDEVDADIPAMIGTSAALALSGIPFEGPIGACRVGHLDGEFVLNPTFSQTAESDLDLVVAGTQDAVLMVESEANLLPESTMLDAVLYGHEQMQVAIDTINDLAAEAGKPRWDWQPPAKNESLDSAVAELVRSDLEAAYQIADKQERSERVGALRDKAVEALADEEREGWGAGDVGEAFKTLEKKIVRGRILAGHPRIDGRDNQTVRPLNVQAGVLPRTHGSAIFTRGETQAIVVSTLGTGRDAQVIDALEGERREPFMLHYNFPPYCVGETGFIGTPKRREIGHGKLAKRGVEAVMPSDEEFPYVIRVVSEVTESNGSSSMATVCGTSLSLMDAGVPLKAQVAGIAMGLIKEGDEFAVLTDILGDEDHLGDMDFKVAGSKDGVTALQMDIKIDGITREIMEQALDQARSGRLHILEQMNQVIDKPREQMSEYAPRLLTMRIDPERIRDVIGKGGATIRGLTEETGTNIDISDEGVVTIASADKAAAEEAKKRIELLTADVEVGKVYDGKVAKLMDFGAFVNILPGRDGLVHISQISNNRVENVADELSEGDSVRVKVLEVDRQGRIRLSMKAVEEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_METNO
Sequence: MNAPVNPKKLIKGALGDWEVVIGMEIHAQVTSRSKLFSGASTAFGAEPNDNVSLVDAAMPGMLPVINRECVAQAVRTGLGLKAQINHRSVFDRKNYFYPDLPQGYQISQYKSPIVGEGEVLVDLPEGETIRVGIERLHLEQDAGKSLHDQHPSLSFVDLNRSGVALMEIVSKPDLRSAEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEFLGTRCEIKNVNSIRFIGQAIEAEARRQIAILEDGGVIEQETRLFDPNKGETRSMRSKEEAHDYRYFPDPDLLPLEIDDAFIDELKTELPELPDTKKARFVAEYGLSAYDATVLVAERASADYFEAVARGRDGKAAANWVINELFGRLNKEGHGIEDSPVSAEQLGAIIDLIADGTISGKIAKDLFEIVWSEGGDPRAIVESRGLRQVTDTGAIEAAVDQIIAANPDKVVQAQAKPTLLGWFVGQTMKATGGKANPAAVNALLKAKLGIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: YGHU_ECOLI
Sequence: MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDASDFETNTEDKRQG
What is the function of this protein?
Exhibits a robust glutathione (GSH)-dependent disulfide-bond reductase activity toward the model substrate, 2-hydroxyethyl disulfide; the actual physiological substrates are not known.  Also displays a modest GSH-dependent peroxidase activity toward several organic hydroperoxides, such as cumene hydroperoxide and linoleic acid 13(S)-hydroperoxide, but does not reduce H(2)O(2) or tert-butyl hydroperoxide at appreciable rates.  Exhibits little or no GSH transferase activity with most typical electrophilic substrates, and has no detectable transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) with glutathionylspermidine (GspSH) as the nucleophilic substrate.
What are the official names of this protein?
Disulfide-bond oxidoreductase YghU, GSH-dependent disulfide-bond oxidoreductase YghU, GST N2-2, Organic hydroperoxidase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Nu-class GSH transferase family.
Protein: NSP1_ROTBA
Sequence: MATFKDACYHYKKLNKLNSLVLKLGANDEWRPAPVTKYKGWCLDCCQYTNLTYCRGCALYHVCQWCSQYNRCFLDEEPHLLRMRTFKDVVTKEDIEGLLTMYETLFPINEKLVNKFINFVKQRKCRNEYLLEWYNHLLMPITLQALTINLEDSAYYIFGYYDCMECENQTPFQFVNLLEKYDKLLLDDRNFHRMSHLPAILQQEYALRYFSKSRFLSKGKKRLSRHDFSDNLMEDRHSPTSLMQVVRNCISTHMNDCEWNKRCHVIVDAKNYISIMNSSYTEHYSVSQRCKLFTKYKFGIISKLVKPNYIFSNHESYALNVHNCKWCQINNHYKVWEDFRLRKIYNNIMDFIRALVKSNGNVGHCSSQESVYKYIPDIFLICKKEKWNEAVKMLFNYLEPVDINGTEYALLDYEVNWEVRGLVMQNMDGKVPRILNMNDTKKILSAIIFDWFDTRYMRETPMTTSTTNQLRTLNKKNELIDEYDLELSDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: SSRP_BRUSI
Sequence: MNKPKNSPARKMIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQANIAESYASFEDGEFWLINSYIPEYTQGNRFNHEPRRLRKLLVSRREMSRLFNSVSREGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLLRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DAPB_EXISA
Sequence: MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALLPDLLAFGRERNIPLVIATTGFTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVPLTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTPIYERTSRREARGAEELGMHSIRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEEATHVTHKRL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGB_DROME
Sequence: MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHVGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSGSDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEASSDEEGEEEEDDDEDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHSFDLQVANWRMERLEVDSKSNSDEEFFDCLDTNETNSLAKWSSLELLGEGDDSPPPHGGPSSAASVGGRGNSRQEDSIFNQDFLMRVASERGNKRQLRSSASVDRSHDSSPPGSPSTPSCPTTILILVVHAGSVLDAASELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIKMVPCPSICTDALGILSSLSPYSFDASPSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAAANIVYHEFLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSNGSQPGTASGASNSGGDAATNINTHNPLSPRNSRLDDDERFIEADLDAKRLLVAPSPRRRRSSSSSDSRATKLDFEVCDFFMFGSPLSVVLAARKLHDAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLHLLEVIQSHPQHFNDGNNLLAGRRLSDASMQSTISGLIENVSLSTIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVIAFILRQIGKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQEGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGYGIYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVRAGAVDVCRHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNNLVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLAGLQAVGGSRPAKGNARMVIPRGCFNLPGQTANPRRRRYLERKTVSSCCLMVFQTT
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes (PubMed:22822086).  May control phosphatidylinositol concentration in transport vesicles from the subrhabdomeric cisternae (SRC) to the rhabdomere (PubMed:1903119).  May function as a calcium transporter (PubMed:1903119).
What are the official names of this protein?
Protein retinal degeneration B, Probable calcium transporter rdgB.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
Protein: ATPB_EUCBI
Sequence: MRINPTTSDPAVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAALSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYIRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLTETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEGEKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MSCL_BACSU
Sequence: MWNEFKAFAMRGNIVDLAIGVVIGGAFGKIVTSLVNDIIMPLVGLLLGGLDFSGLSFTFGDAVVKYGSFIQTIVNFLIISFSIFIVIRTLNGLRRKKEAEEEAAEEAVDAQEELLKEIRDLLKQQAKSPE
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  Forms a nonselective ion channel with a conductance of about 4 nanosiemens.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENDO_BPT7
Sequence: MAGYGAKGIRKVGAFRSGLEDKVSKQLESKGIKFEYEEWKVPYVIPASNHTYTPDFLLPNGIFVETKGLWESDDRKKHLLIREQHPELDIRIVFSSSRTKLYKGSPTSYGEFCEKHGIKFADKLIPAEWIKEPKKEVPFDRLKRKGGKK
What is the function of this protein?
Junction-resolving enzyme that selectively binds and cleaves four-way (Holliday) DNA junctions present after viral genomic replication.  These intermediates are created during DNA repair, processing of stalled replication forks and homologous genetic recombination.  Introduces two nicks on the two non-crossing strands, at 5' sides of the junction.  Participates also together with gp6 in the degradation of host chromosome to provide nucleotides for phage DNA synthesis.
What are the official names of this protein?
Endonuclease I, Gene product 3, Gp3, Junction-resolving enzyme gp3.
Protein: SFGH1_ECOK1
Sequence: MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAENEKLPVLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPNLVMHHFPATARKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase FrmB, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.