PharMolix/UniProtQA huggingface dataset:
Protein: HCP_ECO7I
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETSKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_POPTR
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQSVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGTGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAIGWLGHPLFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGSRTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LBX1_XENLA
Sequence: MTSKDEAKSSASSVEERRRNALDLLPPPANSNKPLTPFSIEDILNKPSVRRSYTICGTAHLLSSADKPPAAGLPLSSRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESTKKMSPSAVEAVLTISELEESGSERGNSRSRSPQLGLTSNHMPLSPSXPLTDQHASKECSEDEEDVEIDVDD
What is the function of this protein?
Transcription factor that controls hypaxial muscle development by down-regulating myod1 and cdkn1b/p27, thereby allowing myoblasts to proliferate before the onset of terminal differentiation.
What are the official names of this protein?
Transcription factor LBX1, Ladybird homeobox protein homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGAL_HALLT
Sequence: MRLGVCYFPEHWPSEEWERDVAAMADAGLEYVRMAEFSWGVLEPERGTFDFEWLDEAIELIGDHGMQAVLCTPTATPPKWLVDERPSIRQEDPDGTVREHGSRRHYCFNSDAYREETARIVERVTERYADSPHVAGWQTDNEFGCHETVRCYCDDCADAFRTWLADRYGDIDRLNEAWGNAFWSQQYGSFDEIDPPGPTPAEHHPSRLLAYARFSSDSVVEYNRLHADLIREADPDWFVTHNFMGRFPTLNAYDVSEDLDRVAWDSYPTGFVQDRYDGEASPDQLRAGDPDQVGMDHDIYRSALDRPFWVMEQQPGDVNWPPHCPQPGEGAMRLWAHHAAAHGADAVLYFRWRRCLEGQEQYHAGLRKADGSPDRGYADAAHTSEEFATLDGASHVDAPVAVVFDYDSLWALNAQPHAPDFDYWALQEAFYGAVRGRGVQVDVVPPSADLSGYAAVVAPALHLVTEDLADRLTDYIAGGGEVLFGPRTGVKDAENKLRPMSQPGPLTDLVGATVDQHESLPRRLETTVRRVGDPTDDSEEIAAPPVSFRTWAEWLDPDAAEPQYAYDVDGPADGRPAVVTNTVGDGQVTYCGVWPESDLADALASDLLDRAGVRYAERLPDGVRIGYRGGRTWVTNFTSDRLRLPEIDPESLAVDDTDRDGFDPMADDDKDSSADGIVVGPYGVAVIEGDCVDGLRIAQT
What is the function of this protein?
Cleaves o-nitrophenyl-beta-D-galactopyranoside (ONPG) in vitro.
What are the official names of this protein?
Beta-galactosidase Bga, Beta-gal.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: CP2D9_MOUSE
Sequence: MELLTGTDLWPVAIFTVIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLADKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNPESSFNDENLLMVVRDLFGAGMLTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPVNLPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSVPDGQPQPSNSGVYGILVAPSPYQLCAVVRDQGH
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D9, CYPIID9, Cytochrome P450-16-alpha, Cytochrome P450CA, Testosterone 16-alpha hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PSS1_ARATH
Sequence: MEPNGYRKERRKEQHLGRMNGGGGDVETDLDPWTAWAYKPRTISLLLIGACFLIWASGALDPDSTTSDDLVTSVKRGVWAMIAVFLAYSLLQAPSTVLIRPHPAIWRLVHGMAVIYLVALTFLLFQRRDDARQFMKFLHPDLGIELPEKSYGADCRIYVPDHPTNRFKNLYDTVFDEFFLAHIFGWWGKAILIRNQPLLWVLSIGFELLEVTFRHMLPNFNECWWDSIVLDILICNWFGIWAGMYTVRYFDGKTYEWVGISRQPNIIGKVKRTLGQFTPAHWDKDEWHPLQGPWRFIQVLTLCIIFLTVELNTFFLKFSLWIPPRNPVILYRLILWWLIAIPTTREYNSYLQDRKPVKKVGAFCWLSLGICIVELLICIKFGSGLYPTEMPLWVVTLWGSVGLGLVAFLLSWTWKIQKILAQKRR
What is the function of this protein?
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine.  Is essential for phosphatidylserine (PS) biosynthesis and PE seems to be the most plausible substrate.  Plays an important role in microspore maturation.
What are the official names of this protein?
CDP-diacylglycerol--serine O-phosphatidyltransferase 1, Phosphatidylserine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope. Note=Mainly localized in nuclei and ER membranes during pollen development.
Protein: DPCKG_THEVO
Sequence: MLLRSGSKYIITAEAREEIKKRNGKLVTIDEMVEVSKSTQLDSVGDVTTTNLRRAGAKLFLQIVDLKTKRGESIFQHEEGSITVRNDPGTISFDLIEAIKSSIENNKPTRIEVIGEEDLAVLPIIYYSKNNTVIAYGIPDVGMAALTVTDDLRDHVTEVIAKMAIE
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: BETA_PARXL
Sequence: MAANEYDYIIVGAGSAGNVLASRLAEDADVTVLLLEAGGPDYRFDFRTQMPAALAYPLQGRRYNWAYETDPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNALDYDGWAAHAGLENWTYLDCLPYFRKAETRDIGANAYHGGDGPVHVTTSKPGNNPLFAAMVEAGVQAGFPRTDDLNGYQQEGFGPMDRTVTANGRRASTARGYLDRAKARPNLTIVTHAVTDRVLFSGKRAVGVSYLHHGNVLNAQARREVLVCSGAIASPQLLQRSGVGRSTWLRELDVPLVHDLPGVGENLQDHLEMYIQYECKEPVSLYPALQWWNQPAIGLEWMLNGTGIGASNQFEAGGFIRTRDDDPWPNIQYHFLPVAINYNGSNAIRMHGFQAHVGSMRSPSRGRVKLTSRDPNAHPGILFNYMADPLDWREFRDGIRITREIMRQPALDRYRGRELNPGAELTTDEQLDSFVRMRAETAFHPSCSCKMGYDDMAVVDNEGRVHGMQGLRVVDASIMPRITTGNLNAPTIMLAEKIADRIRGREALARVDTPYFVANGVASRKRESATV
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: SSRP_CALS4
Sequence: MSKEKEEIKIIAQNRKAFHDYFIEETYEAGIELVGTEVKSVRQGKVNLKDSFARVENNEVILYNMHISPYEKGNIFNKDPLRPRKLLLHRHEINKLSGYVSRKGYTLIPTKVYLKRGLVKVELAVAKGKKLFDKREDIARRDAKRELEKQFKEKQLGI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MCFD2_HUMAN
Sequence: MTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ
What is the function of this protein?
The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.  Plays a role in the secretion of coagulation factors.
What are the official names of this protein?
Multiple coagulation factor deficiency protein 2, Neural stem cell-derived neuronal survival protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
Protein: MIAB_CUPNH
Sequence: MKKVFVKTYGCQMNEYDSDKMVDVLNASQGLEPTDNVEEADVILFNTCSVREKAQEKVFSELGRMKALKAVKPDLVIGVGGCVASQEGASIVSRAPYVDVVFGPQTLHRLPDLIARRQRTGQSQVDISFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGEEVSRPFEDVLAEVAGLAEQGVREVTLLGQNVNAYRGKMGDTTEIADFALLIEYVAEIPGIERIRYTTSHPKEFTSRLVELYGRCDKLVNHLHLPVQHASDRILMAMKRGYSVLEYKSIIRKLRVLRPDMSMSSDFIVGFPGETDADFEKLMAMIEEIGYDTSFSFIFSPRPGTPAANLHDDTPHEVKLRRLQRLQATIEENVQRISQNMVGTVQRILVEGPARKDPTELHGRTENNRVVNFALPGVPQAGRDRLVGQLVDVSITQAFPHSLRGEIVVRQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_SALPK
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ERA_THEPX
Sequence: MGHKAGFVALVGRTNVGKSTLLNAILQEKIAITSPKPQTTRNTIRGILTTDEYQVIFVDTPGIHKPKSKLSEFMIEVAKRTLKEVDLILYMIEPDTEVGPGDRYIIEHLKEVDTPVILVVNKIDLVPEKRVEETIKIFKEQYEFKDVVAISAIENKNIDLLKEKIVSLLPEGPKYYLDDYITDQPEKLIVAEIIREKMLHFLEEEVPHGVYVEVESIKEREDKDIIDIEAYIYCEKESHKGIIIGKNGQMLKKIGQSARLDLEEFYGKQVFLDLWVKTRKGWRDNTTLLKKLGYAIDKKTYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: PIMT_ECO45
Sequence: MVSRRVQALLDQLRAQGIQDELVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_STRP7
Sequence: MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYKEIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNAEAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARFFAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNHPDVTIIADAEALSLLEK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: HFQ_XANCB
Sequence: MAKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSNENNQAEDDDVEQ
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL34_CAMLR
Sequence: MKRTYQPHKTPKKRTHGFRVRMKSKNGRKVINARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PLSX_FRATT
Sequence: MGYKISIDAMGGDHGLNTTIPAALEAVKKDSNLQIVLVGDHHKIKRALDRYSKVKKIKLPVLQRIAIHHASETVGMDESPSIAVRKKKDSSMRVAINLVKDRTVDACVSAGNTGALMATSKFVLKTINGVDRPAIVYALPAFNRETKQLSKTYMLDLGANVVCTSEQLFQFAIMGSILAASSKGIAEPRVSLLNIGEEEMKGLDNIKNAAKLLQGCDFINYNGYIEGKYIFDDTTDVIVCDGFVGNVSLKTMEGSLRLIESLIKKTIQESSLLMKIPIVMALPIFKKMKKGMNLDSFNGASLLGLTGIVVKSHGGASANAFETAIYEAIKEIKYNIPKTIQESLEKVL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: EF2_ENTHI
Sequence: MSSTGVKTMKDFMLNKSNIRNMCVIAHVDHGKSTLTDSLVTLAGIISNEKAGVARYTDTRPDEQERCITIKSTSISMYYEIEDKEDIPADANGNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVEGVCVQTETVLRQALTERVKPIVIINKVDRVILELKEEPEEAYQSFCRSIENVNVLISTYKDELLGDVQVSPGEGTVAFGSGLHGWAFTLEKFAKMWSAKFGIDRKRMLEKLWGDNYWDAKAKKWKKNGKGDHGEVLQRGFVQFCFDPITKLFNAIMEGRKADYEKMLTNLQIKLSADDKEKEGKELLKTVMKLWLPAGVTLLEMIVLHLPSPVVAQKYRTSNLYTGPMDDEAAKAMANCDEKGPLMMYVSKMIPTNDKGRFYAFGRVFSGTIRTGGKARICGPNYVPGKKDDCVIKNIQRTMLMMGRYTDPIDECPCGNVIGLVGVDQYLLKSGTITDSVAHIIKDMKFSVSPVVRVAVETKNPSDLPKLVEGMKRLSRSDPLCLCYTEESGEHIVAGAGELHLEVCLKELQEDYCSGVPLIVTEPVVSFRETITEPSRIQCLSKSANNQNRLFMRAFPFPEGLAEDIEAGEIKPDTDFKERAKFLSEKYGWDVDEARKIWCFGPDNCGPNLFVDVTKGIQYLNEVKDSIVNGFNNAMHDGVVCNEQIRGVRINLEDVKLHADAIHRGGAQMIPCARRCCFACVLTGAPSLLEPMYLAEIQCPESAIGGIYTVMSRRRGKIISEEQRPGTPLFNVRAYLPVCESFGFTADLRSHTSGQAFPQCVFDHWQLLNGDVTDATSKVGSIVAAIRKRKGLPEGVPGLDKFYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIH_HUMAN
Sequence: MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357).  Participates in pre-mRNA splicing.  May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.  May act as a chaperone.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase H, PPIase H, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, CypH, U-snRNP-associated cyclophilin SnuCyp-20, USA-CYP.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
Protein: SPXM1_ORYSJ
Sequence: MVNFGKRLMADQLEEWKEYYINYKMMKKKVKQYVQQTQNGGRNREQVLKEFSRMLDDQIEKIVLFLLQQQGHLASRIEKLGEERALLMEQADASQISELREAYREVGIDLMKLLRFVDMNATGIRKILKKFDKRFGYKFTDYYVSTRANHPCSQLQQIFKQVGIVAVVGALSRNLAFLQDHQGNFPSIYDHPSITLKDPIIEQINHSVQKLTHATNLLQFIGQHALIIPEDMHSGSEDLVDDQSYHFMSLLLNLANTFLYMVNTYIIVPTADDYSVSLGAAATVCGVIIGSMAVAQVFSSVYFSAWSNKSYFRPLVFSSIMLFLGNLLYALAYDVNSLTVLIVGRLLCGLGSARAVNRRYISDCVPLKTRLQASAGFVSASALGMACGPALAGLLQTNFKIYGFTFDQNTLPGWIMCLAWITYLFWLWISFKEPDHIVRENSVNTPSSDSGHRRNSNLEDGLAQPFLIDAKESLDENGEDNDENEEDPEDSHKPATSLAAAYRLLTPSVKVQLLIYFMLKFAMEILLSESSVVTTFYFNWSTSTVAMFLAVLGLTVLPVNVIVGSYVTNLFQDRQILVASEIMVLIGIAMSFRFTSHYSVPQYVSSALITFVFAEVLEGVNLSLLSRVMSSRLSRGTYNGGLLSTEAGTLARVAADMTITAAGYLGQNSLLNVTLLPSFVICVASIVATFCTYNSLY
What are the official names of this protein?
SPX domain-containing membrane protein Os02g45520.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: T1S_SALTY
Sequence: MSGGKLPEGWATSTINEMCNLNPKLKLDDDLDVGFMPMAGVPTTYLGKCNFETKKWSEVKKGFTQFQNDDVIFAKITPCFENGKAVVIKEFPNGYGAGSTEYYVLRSINGLINPHWLFALVKTKDFLTNGALNMSGSVGHKRVTKEFLENYGVPVPPLAEQKVIAEKLDTLLAQVDSTKARLEQIPQILKRFRQSVIVAAVNGQLTKELHKKNKFKLTELNISIPSLWKISEIGQFADVKGGKRLPKGESLIAENTGFPYIRAGQLKNGTVLPEGQLYLEEYIQKSISRYTVSSGDLYITIVGACIGDAGIIPDVYNNANLTENAAKICNLNENIFNRFLSLWLRSSYLQDIINSEIKSGAQGKLALARIKSLPLILPPLQEQHEIVRRVEQLFAYADTIEKQVNNALTRVNSLTQSILAKAFRGELTAQWRAENPELISGENSAAALLEKIKAERAASGGKKTSRKKA
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues of the sequence 5'-GAGN(6)GTRC-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated (PubMed:3025838, PubMed:12654995).  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (By similarity).
What are the official names of this protein?
Type I restriction enzyme StySJI specificity subunit, S protein, Type I restriction and modification system SB, Type I specificity subunit S.StySJI, S.StySJI, Type-1 restriction enzyme StySJI specificity subunit.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: MZF1_HUMAN
Sequence: MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGPSWREHPRALWHEEAGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREGGFAHALLLPSDLRSEQDPTDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE
What is the function of this protein?
Binds to target promoter DNA and functions as transcription regulator.  Regulates transcription from the PADI1 and CDH2 promoter.  May be one regulator of transcriptional events during hemopoietic development.
What are the official names of this protein?
Myeloid zinc finger 1, MZF-1, Zinc finger and SCAN domain-containing protein 6, Zinc finger protein 42.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDA2_ZYGRC
Sequence: MNFETGQDKTSNAPIPKDKLSELIKSTYDNLERSGNASVDQLLKSLLEQLNSHSSLYKYIVSISTLETGSETIDSENCTMSNAIGASWNSRKDGLFNYDLPDNEHRGVKHLVTVIWVAK
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: VATF_HALVD
Sequence: MSQEIAVIGSPDFTTGFRLAGVRKFENVPDEAKDDELDEAVTRTLEDEDVGIIVMHEDDLDHLSRNARQSVERSIEPTLVTLGGSGGASGLRDQIKRAIGIDLMDE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RL24_RHILW
Sequence: MQKIRKGDKVVMLAGKDKGRTGEVVQVMPKEDRAVVRGVNVVKRHQRQTQTQEAGIINKEASVHLSNVAIVDKDGKPTRVGFKVVDGKKVRVAKRSGEVIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.