PharMolix/UniProtQA huggingface dataset:
Protein: CCL28_HUMAN
Sequence: MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY
What is the function of this protein?
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils.  Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
What are the official names of this protein?
C-C motif chemokine 28, Mucosae-associated epithelial chemokine, MEC, Protein CCK1, Small-inducible cytokine A28.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_HYDCU
Sequence: MAIIKKSKPTSPGRRFVVSVVEPDLHKGKPFSALLEKKSKSGGRNSNGRITVRHQGGGHKQHYRQIDFKRNKDGVAAVVERLEYDPNRTAHIALLKYADGERRYILAPRHVKAGDPVESGEHVSIKAGNALPLRNIPVGTVVHALEMRPGKGAQIARSAGAYAQIAGRDGAYVLVKLRSGEMRKILADCRATIGEVGNQEHSLRKLGKAGAKRWKGVRPTVRGVAMNPVDHPHGGGEGRTSGGRNPVTPWGVPTKGKKTRSNKRTDRMIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FLGM_YEREN
Sequence: MSIDRTQPLLPVTQVQPRETSDIAQQTRKPSAQSKTPVSGTEVKLSDAQAKLMQPGSQDINVERVETLKQAIRSGQLTMDTGKIADALLKNVADDLKSS
What is the function of this protein?
Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective.  It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity).
What are the official names of this protein?
Negative regulator of flagellin synthesis, Anti-sigma-28 factor.
What is the protein family that this protein belongs to?
Belongs to the FlgM family.
Protein: RIMM_ECOLC
Sequence: MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_ACIET
Sequence: MSKRDFYEVLGVPKNASDDELKKAYRKLAMKYHPDRNQGDAAKPAEEKFKEAKEAYEILSDAQKRAAYDQYGHAGVDPNMRGGMGGAEGFGGFAEAFGDIFGDMFGGARGRGGRQVYRGNDLSYAMDVTLEEAAKGKEAQIRIPSWESCETCHGSGAKPGTSAKTCGTCQGSGTVQMRQGFFSVQQTCPHCRGTGKIIPEPCTACHGQGRVKKQKTLEVKIPAGIDDGMRIRSTGNGEPGTNGGPPGDLYIEIRIRKHDIFERDGDDLHCQVPVSFITAALGGEIEVPTLQGKAAIDIPEGTQAGKQFRLRGKGIKGVRASYPGDLYCHIIVETPVKLTEHQRKLLKELDESLKKGGAKHSPSTESWTDRLKSFFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_THEP1
Sequence: MTVERLENGVIVQRNTNEIEISITLDTVHGKLEGSTGVNFFDHLLNTFCHYSGLGLRVSTCESKDGILHHLIEDFGISLGLAFRELFDYTKVRRFGEATVPMNEALVGCYVDLSGRPFFQKNFEFSVEKIEDMPVEGFEEFMCGFVNHARITVHFFKFFGKNDHHISESAMKSFGLAIARALEGSEKKTTKGVID
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA21_ARATH
Sequence: MKVVAAFLLAVLSGKASPTTGDIKDILGSVGAETEDSQIELLLKEVKGKDLAELIAAGREKLASVPSGGGGGVAVASATSGGGGGGGAPAAESKKEEKKEEKEESDDDMGFSLFE
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: CCA_ARCFU
Sequence: MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARNTWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVHGVVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLKGFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDVAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGFFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFEFLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDERNVKKFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKNVGESIREYFEIISGEKLFKEPVTAELCEMMGVKD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: VEF_GVTN
Sequence: MSYKVIVPATVLPPWLRVGENWIFARHRRTEVGVVLPANTKFRVRADFSRAGFTRPVIVRLLNNNRSTEREINLNNDQWMEVEHAHESVPFVDWLVGEKNTMAEVYFEIDGPHIPLPVYVFNTRPVEHFKSEYRQSSSGYCFLYLDLVCMLVPPASKNALLDVNIFELHQFYNEIINYYDDLCGLVEDPYADTVDSNLPNKAAFVKADAGGPGGAYYGPFWTAPASSNLGDYLRISPTNWMVIHELGHAYDFVFTVNTILIEIWNNSLCDRIQYKWMNKIKRQQLARVYENRRPQKEATIQALIDNNSPFDNWGFFERLIIFTWLYNPQRGLDTLRNINHSYRVHATRNSSIPYPQIWSWLTTSAYDNFWLYFNLVGVYPADFYVNEHNKVVHFNLHLRALALGQSVRYPIKYIITDFDLVSKNYDIKQYLESNFDLVIPEELRQTDLLADVRVVCVIDDPSQIVGEPFSVYDGNERVFESTVATDGNMYLVGVGPGVYTLRAPRGKNKRYKLHLAHSPREPVHPANDHMYLLVTYPYYNQTLTYTPYVNSDLAVDMAHLFGSNDRRYVATIYFNPFEQTVTVHLNNIRAGRENNTTLYFEMVISNPFNGQSQTFTILEDNPTLRQGYYKFDVVTYSSIRLNMSVAGRLLFRRYIFAGGTTTLTMFPNQVLEPNLFPDGSALNRTLARLREQAAFLDNYSQLMYIENELRDTIYLASQLVDPASDEFVKYYPDYFRDPHTYVYLFRFRGLGDFVLLDLQIVPLLNLATVRIANIQNGPHSYFDTLYFKVELRDTNGAIVFSYSRRGNEPMTPEHHKFEVYSGYTVELFMREPGNRLQLIVNKMLDTALPSTQNIFARITDTQLVVGDTSIEDNLVTSINVDCGDDDNQKIRVVETLKMIAF
What is the function of this protein?
Involved in disruption of the peritrophic membrane and fusion of nucleocapsids with midgut cells.
What are the official names of this protein?
Viral-enhancing factor, Enhancin, VEF, 104 kDa glycoprotein, Synergistic factor.
Protein: APH1B_HUMAN
Sequence: MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVSGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLCQDKNFLLYNQRSR
What is the function of this protein?
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein).  It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.  Probably present in a minority of gamma-secretase complexes compared to APH1A.
What are the official names of this protein?
Gamma-secretase subunit APH-1B, APH-1b, Aph-1beta, Presenilin-stabilization factor-like.
What is the protein family that this protein belongs to?
Belongs to the APH-1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NU4LM_TRAPO
Sequence: MPIIYMNIMLAFLISLLGMLIYRSHLMSSLLCLEGMMLSLFIMSTLMALNMHFPLANIVPIALLVFAACEAAVGLALLVSISNTYGLDYIHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLF20_ARATH
Sequence: MVLSKKTIMQSFALMIILSIVMSTTEAKTIGNPAMREDEPKGCPPGSPASCKMQPANPYKPGCEASQRCRGT
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 20.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KCY_BORT9
Sequence: MVIAIDGPSASGKSSIAKALGMRLGFKFISSGYFYRIITLIAQRFSLNEYDLLSESKILELVSQNDIKFNGFDFLLNGTNVISHILNERIDFQVSLYSSYIGVRNIVNKKLREIVKLKDDNYIIEGRDITTVVFPEAEVKIYLDASVKVRALRRYNQRSDNVTLNELEQALERRDEIDQNKEYGKLKLDKEVFYIDTSYKCLDDVCNIIIKTFNLKKKVIER
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMTAB_PYRAB
Sequence: MVKIYIENYGCARNRADGEIMAALLHLAGHEIVYDPDEGEIVVVNSCAVKDPTERKIARRIKELLDSGKKVIVTGCLPHVNPDVIDERVSGILGVKSIDRIIQAVEYALRGEKLISVPDWRKRNLDKLDFPRLSPRTVYFIVPIAEGCLNACTYCATRFARGVLKSYSPEKIVGWVKWAIKQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRVRVGMMNPNHVLKFLDELIEAYQDEKIYKFLHLPVQSGDNDILRRMGRNYTVEEFEEIVKEFRKKFPDLNLHTDIIVGFPGEDDEAFQRSVELIRRIRPDKVNVSRYSPRPGTIAAKWKQLPGWIVKERSRLLHRIRLQISYEINQKYIGKKVEVLIHGEGKKGNVDAVTMNYKHVILPFGNSGEFRIAEIKNATSTYLLGEVMS
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Probable threonylcarbamoyladenosine tRNA methylthiotransferase, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Protein: PAND_KOCRD
Sequence: MLRTMFTGKIHRATVTQADLHYVGSVTVDQDLLDAAGILPGELVAVVDVTNGARLETYTIAGERGSGVLGINGAAAHLVHPGDLVILIAYGLMDTAEAQTYEPRVVHVDERNRIVALGSDPADAVVGDVVRPPHAREHGRAREDAATTRA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1AB_MASV1
Sequence: MANNTTSALHPRGSGQRCVYDTVLRFGDPDARRRGFQLDEVSHNKLCDIFDSGPLHFAFGDLKVMKVAGGVVTPHKTVVKTVYVSGVQEGNDYVTFAFTPGPNEWREVDPRIDKRTALVGVLVQEHKKLDSDLKESRRELSQLKLEHSLLRHDYERLVREKPGPAMRTFKFSAVIFYAFFLGFLLMSAVKGEVYGRCLDSELNLNGNPEVCLHWEEVKSFSLQVALADFWNMTLDYYATVAPQSPLMDLALGYFPYFANWHMAAFLVGTAHVVAAERPLYMLVTLVLATLSRFQLVALAAVPMLDMPSSIGLWVTMVLFAIDQAFAILASVLISVLLLILCLAMNDVDYGALLRGCVTLVSATVFSHLVSFLHAPGWFTIIAILIYRIPKVLSYVSAERVDIKGPDGKIKETQNANPSWITKMSGLKNFFQRAFRQKVRTGVNPTTRIIPNSLVVIDAKDGRGTGFRVRNYLVTAGHVVGADTTVRVRWADVTSFAHVVYRVPNKDIVLLTLPAEYNSLHSYKLAKEVVDGTVVVVSNGDGGALSVGISEGVIVGESMTYAINTADGMSGSPLTTTDGRLIGVHQQNTGFTGGAVIFRDTDFPQPKKPQREADLEAKVAELEKALAAYTQSATGEDIVGLVRVAIQREMEVLRKELSNEFGQAKGKTKHKRRIMAAARSGGKRKPGKVWTEEEYKKLLEEGFTRDQLREMAEAAREADDDFDDYEEEKNEVDYPVWSDHDSDEEIDRDWFGQNLPTWSSAWSDFEPELDPDVTKTLPCHLEDKFSLKHYIITEADLKHFGQEMKEYMDHLDAVIKTHTEKGKWCPNTNTEEILKDLNAMWFKLNHTMWKNGVAPFMQRKKQKPKKREEGPERGPINPDEMRLDHWEKMMAPPDAGRRLVPDDYPVIGKLPINRPISDWDEPVDDLLNLLPPAPDSSAYGPAVWGPEAYVKSFEKFTYAKPRDSIKRDFPREWKFACQVLRREFDFLEGSVIMDITATSKNADSTCAYPKCNYWKTEAEYLSERGYQDYVSEYKRIHGGARPKVLWLLFLKKEILKVKKINDSDIRQIVCADPIFARIGNAFEEHQNTLMKHRTATRMPQCGWTPFFNGFKRRIERLLSRKNSVFIEFDWTRYDGTIPREIFAKIKSFRFSCLAEEFQTDANRAMYQWYCDSLLDRYVLMPSGEVTRQTKGNPSGQISTTMDNNLCNVFFQAFEYAYIHPEKSIEELRESWDRCDSLIYGDDRLTTFDHVPPDYVDRVVHMYKDVFGMWVKPEKVIVSDTPVGLSFCGFTVGPDLMPVPTDCDKLVASLVTPTKKLQDIVALYSKVLCYRILGHNLSDEHEFKRYVRVALEVLARHIRNLGGEEPVHVTERLLDKLWRGGPK
What is the function of this protein?
Protein covalently attached to the 5' extremity of the genomic and subgenomic RNAs.
What are the official names of this protein?
Non-structural polyprotein 1AB.
What is the protein family that this protein belongs to?
Belongs to the astroviridae polyprotein 1AB family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RBFA_LEIXX
Sequence: MADPARARKLADRIKVIVAERLDRGLRDPRLGFVTITDVQVTGDLQHATVFYTVYGTDQERADTAAALTAATGMLRSEVGKNITARLTPTLQFQLDAIPENAAHIEDLLRQARDHDTEVAGLAEGAAYAGEQDPYVKPREAN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMM9_ECOLX
Sequence: MELKHSISDYTEAEFLQLVTTICNADTSSEEELVKLVTHFEEMTEHPSGSDLIYYPKEGDDDSPSGIVNTVKQWRAANGKSGFKQG
What is the function of this protein?
This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
What are the official names of this protein?
Colicin-E9 immunity protein, ImmE9, Microcin-E9 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.
Protein: ILVD_PYRAE
Sequence: MVKIRIRSPLWYDGVDNAPHRSYLKAIGFTEEDFSKPIVGVLASWSELGPCNYHTLELAKYVKEGIKEAGGVGLAAPTIVVNDGINMGTPGMRYSLISRDLIADTIEAQFNAHGVDAWVGIGGCDKTQPGIMMAMVRLDIPAVYLYGGTAEAGWLGERELTIEDTFEAVGAYLAGRITLEDLKRIEELSFPSYGTCQGLFTANTMAMIGEALGLSLLGSASPPATSSRRRAFAIASGRAVLKAAELGITPRKVVTYDALYNAAVTLFATAGSTNAILHLLAIAHEAGVKFTLDDFDEISKKVPVIAALRPAGPYAMQDLDKIGGVPRILKKLYKAGLLRGEALTVEGETIGKLLDRWQPPPLPEAGVLYDVDRPYKPYSGIRILRGNLAPNGAVMKVGAAERLKFEGRAKVYDSEAEAFKAVASGEIKAGDVVVIRYEGPKGAPGMPEMLKITAAIVGAGLGEVVALITDGRFSGATRGIMVGHVSPEAAVGGPIALVQNGDRIVIDGEAGLLKLELGEEELERRRKNWSPPPPKYKGGLLAKYASLVQQADKGAVTSPPVL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SYL_ECO81
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_DEBHA
Sequence: MFTIYTYLAPIVAMVLVVLNYLISNNNSYIEKDGPFECGFTSYQQTRSAFSVAFILVAILFLPFDLEMSSILPYVVSAYSNGTYGLSILVIFLLSLVIAFVYEINLGALNLERRYTPIVKPLMNKLYL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TTCA_PARDP
Sequence: MRDETGETQDLEAEEIHPLFHGAPGSTEFRKLRKRLVRETRAAIETYDMIRPGDRWLVCLSGGKDSYTLLAVLHELKWRGLLPVELLACNLDQGQPGFPATVLPEFLTQRQVPHRIEYQDTYSIVKEKVPEGRTYCSLCSRLRRGNLYRIAREEGCQAVVLGHHRDDILETFFMNLFHGGRLASMPPKLLNEEGDLNVLRPLAFVAEADCDRFARAMNYPVIPCDLCGSQEGLQRMQVKRLLDEWESRSPGRRRVMFRALMNVRPSHLPDPKLFDFTALMPDMSDFREKDVPILREH
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLCR3_ARATH
Sequence: MEGGSVNESHSNADQMFDTTIEELCKNLCELQSSNQSPSRQSFGSYGDESKIDSDLQHLALGEMRDIDILEDEGDEDEVAKPEEFDVKSNSSNLDLEVMPRDMEKQTGKKNVTKSNVGVGGMRKKKVGGTKLQNGNEEPSSENVELARFLLNQARNLVSSGDSTHKALELTHRAAKLFEASAENGKPCLEWIMCLHVTAAVHCKLKEYNEAIPVLQRSVEIPVVEEGEEHALAKFAGLMQLGDTYAMVGQLESSISCYTEGLNIQKKVLGENDPRVGETCRYLAEALVQALRFDEAQQVCETALSIHRESGLPGSIAEAADRRLMGLICETKGDHENALEHLVLASMAMAANGQESEVAFVDTSIGDSYLSLSRFDEAICAYQKSLTALKTAKGENHPAVGSVYIRLADLYNRTGKVREAKSYCENALRIYESHNLEISPEEIASGLTDISVICESMNEVEQAITLLQKALKIYADSPGQKIMIAGIEAQMGVLYYMMGKYMESYNTFKSAISKLRATGKKQSTFFGIALNQMGLACIQLDAIEEAVELFEEAKCILEQECGPYHPETLGLYSNLAGAYDAIGRLDDAIKLLGHVVGVREEKLGTANPVTEDEKRRLAQLLKEAGNVTGRKAKSLKTLIDSDLTSSSALR
What are the official names of this protein?
Protein KINESIN LIGHT CHAIN-RELATED 3.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
Protein: RS9_RHIEC
Sequence: MADLSSLKDLGTSSEAAAPAHVRKVDSLGRSYATGKRKDAVARVWVKAGSGKIIVNGKDFTAYFARPVLQMILRQPIVAAARDGQFDIIATVAGGGLSGQAGAVRHGLSKALTYFEPGLRSVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS21_BDEBA
Sequence: MAMVKIKDGESFESAFRKFKKSCEKAGILSEVKKRENFEKPSVRLKKKSIAARKRAVKKSRKGWND
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DEF3_MESMA
Sequence: MKTIVILFVLALVFCTLEMGMVEAGFGCPFNQGKCHRHCRSIRRRGGYCDGFLKQRCVCYRK
What is the function of this protein?
Antibacterial peptide active against Gram-positive bacteria (including S. aureus ATCC25923 (MIC=2. 5 uM), M. luteus AB93113 (MIC=2. 5 uM), and the antibiotic-resistant S. epidermidis PRSE P1389 (MIC=1. 25 uM)), but not against Gram-negative bacteria (including E. coli and P. aeruginosa) (PubMed:31954123).  Also blocks the currents of Kv1. 1/KCNA1 (57% inhibition), Kv1. 2/KCNA2 (27. 5% inhibition), Kv1. 3/KCNA3 (IC(50)=23. 4 nM, 84. 3% inhibition), KCa3. 1/KCNN4/IK (15% inhibition), KCa2. 3/KCNN3/SK3 (87. 5% inhibition) and Kv11. 1/KCNH2/ERG1 (30. 4% inhibition) channels (tested at 1 uM) (PubMed:31954123).  It inhibits potassium channel current by interacting with the pore region (PubMed:31954123).
What are the official names of this protein?
Defensin BmKDfsin3.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.