PharMolix/UniProtQA huggingface dataset:
Protein: NAGB_LISIN
Sequence: MQLITTENKLAGSKKALEIIEKGITSGEVNTLGLATGSTPETLYAELVKSDVDTKNVTTTNLDEYVGLAADDPNSYHYYMNDLLFSKKAFKESFLPNGEATDAEAECARYEGILSEHPIDIQVLGIGTNGHIGFNEPGTSFDSLTHKVVLTDSTREANKRFFEREEDVPTHAYSMGIKSIMNAKKIILLAFGENKAQAIKETIKGPVDVNCPASVLQNHPDVTVILDNEAASLL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RISB2_RHILO
Sequence: MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPLHARTLAETGRYGAVLGTAFVVNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNYHDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2, Type II lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: 5NT1B_HUMAN
Sequence: MSQTSLKQKKNEPGMRSSKESLEAEKRKESDKTGVRLSNQMRRAVNPNHSLRCCPFQGHSSCRRCLCAAEGTALGPCHTIRIYIHMCLLWEQGQQITMMRGSQESSLRKTDSRGYLVRSQWSRISRSPSTKAPSIDEPRSRNTSAKLPSSSTSSRTPSTSPSLHDSSPPPLSGQPSLQPPASPQLPRSLDSRPPTPPEPDPGSRRSTKMQENPEAWAQGIVREIRQTRDSQPLEYSRTSPTEWKSSSQRRGIYPASTQLDRNSLSEQQQQQREDEDDYEAAYWASMRSFYEKNPSCSRPWPPKPKNAITIALSSCALFNMVDGRKIYEQEGLEKYMEYQLTNENVILTPGPAFRFVKALQYVNARLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKDPIGYLKAYLTNLYIAADSEKVQEAIQEGIASATMFDGAKDMAYCDTQLRVAFDGDAVLFSDESEHFTKEHGLDKFFQYDTLCESKPLAQGPLKGFLEDLGRLQKKFYAKNERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKSPILVKIRPHIFFDDHMFHIEGAQRLGSIAAYGFNKKFSS
What is the function of this protein?
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, AMP is the major substrate.
What are the official names of this protein?
Cytosolic 5'-nucleotidase 1B, cN1B, Autoimmune infertility-related protein, Cytosolic 5'-nucleotidase IB, cN-IB.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase type 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SHEB8
Sequence: MSRVAKAPVSIPAGVEVTLNEQTLTVKGGKGSLTRVINNAVNVVIEAGVVKFLPVEGVSNAWAQAGTTRALVNNMVVGVSQGFERKLKLVGVGYRAKLVGSDIDLTLGFSHPLVHKLPAGVTAECPSQTDIVLRGVDKQLIGQVAAEIRGYRPPEPYKGKGVRYDDEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ARGB_NEIMF
Sequence: MESENIISAADKARILAEALPYIRRFSGSVAVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVGKKGEFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVESIDTGLVKGLIERGYIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKMGNLLTKLTPKRIDELIADGTLYGGMLPKIASAVEAAVNGVKATHIIDGRLPNALLLEIFTDAGIGSMILGGGEDA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_ALIB4
Sequence: MIDIKLLQKDFDYVVKALQKKGVDNALLNNLKDLALKTKQKRQEMEDVTAEQNLLSKEFGRYKKENLDISELQEKINALKTKKQELEDEVRTLEDDLNSIILSVPNMPDENVPFGVDENENVILEVIGEKPTFNFTPKEHWDLSCDWLDFERGVKLAKSRFTAIKGDGARLERALINYMLDFNRQRGFNEWYVPFMANSNTLQGTGQLPKFADDLFKIEGEDLYLIPTAEVSLTNLYNDEIIDKSELPLLLTSYTPCFRKEAGSAGRDTRGLIRQHQFDKVEMVAITSQEQSDEIFEKMVNCASDLLSSLGLCHQKVQLCSGDLGFSAAVTIDLEVWLPGQNKFREISSISNTRDFQARRAKIRYKEDKKNILAHTLNGSSLAVGRTLLAIMENYQQADGSVKIPEVLKKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECDF_THET8
Sequence: MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLEKARTVLENRINALGVAEPLIQIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKEGATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLLTGADLADARAVFDQFGRPQVSLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASEIALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLVASLGLLYTSALILGLLSGLGATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLRQAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFAVILAIGVVASVFSNLVFSRHLLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGGTAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLELERLFASELKATVLASETVGPAIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILAVAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIVVSDRIRENQKLLRHLPYAELVNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALVVAWKNRRKAQEASKA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecDF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB1_YEAST
Sequence: MVAISEVKENPGVNSSNSGAVTRTAAHTHIKGLGLDESGVAKRVEGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPSTGKTALALAISQELGPKVPFCPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYGKTISHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAYATEFDLETEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVISMMGQLLKPKKTEITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIFTYLNKALESNIAPVVVLASNRGMTTVRGTEDVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRATVERLQVESSALDLLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAKRSTKILETSANYL
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes.  Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates.  The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage.  RVB1 recruits ARP5 to the INO80 complex.  During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes.  Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing.
What are the official names of this protein?
RuvB-like protein 1, RUVBL1, TIP49-homology protein 1, TIP49a homolog.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS1_PROM5
Sequence: MITIALPKGALLEDSISIFKKAGLNFSDALLENNRSLTIESECKRAKALLVRNGDVPVYVSYGQADLGIVGYDVLQESELKVAKLLDLEFGGCHMSLAVKNTSNYSKPTDLPANCKVASKFTKTARAYFDDLNIPVEIVHLTGSVELGPITGMAEAIVDLVATGKTLKENGLSKIDDLFYSTARLIANPLSIRLDSNPLRDVILSIESFKGT
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_ECOHS
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN622_RAT
Sequence: MATYTCITCRVAFRDAEMQRAHYKTDWHRYNLRRKVANMAPVTAEGFQERVRAQRAVAEEESKGTATYCTVCSKKFATFNAYENHLKSRRHVELEKKAVQAVSRQVEMMNEKNLEKGLGVDSVNKDAMNAAIQQAIKAQPSTSPKKAPFMPTDESRRVAGAVRRGTPERDPTEKPPRLQWFEQQAKKLAKQQWEESEEEGEEDDEDWEDIDSDDGLECENPGVEEEDAEDAEAEESPPLGAIPITDCLFCSHHSSSLVKNVAHMTKVHSFFIPDIEYLSDLKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQAHMNDKSHCKLFTDGDAALEFADFYDFRSSYPDYKEGQDPAEIEDLSSEKILECDDETMELILPSDLEYFD
What is the function of this protein?
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
What are the official names of this protein?
Cytoplasmic 60S subunit biogenesis factor ZNF622, Liver regeneration-related protein LRRG121, Zinc finger protein 622.
What is the protein family that this protein belongs to?
Belongs to the REI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYB6_PHATC
Sequence: MNKVYDWFEERLEVQAIADDISSKYVPPHVNIFYCFGGLVLTCFLIQVATGFAMTFYYRPSVVDAFASVEYIMTSVNFGWLIRSIHRWSASMMVLMMVLHVFRVYLTGGFKKPRELTWVTGVTLSVVTVSFGVTGYSLPWDQVGFWACKIVTGVPAAVPIVGEPLVLILRGGESVGQSTLTRFYSAHTFVLPLAAAVLMLTHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FTSB_PECCP
Sequence: MGKLTLLLLILLGWLQYSLWLGKNGIHDYVRVKDDVVVQQGNNAKLKDRNEQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPESNHRNANTAPSTNTPSNNIQR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MDTI_ECO24
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_HALS3
Sequence: MSTQLQHARDGTVTDAMRRVADREGRDPEVVREAVADGHAVIPANHHHDALDPMIIGRDFATKVNANIGNSDTTGDIDDELEKLHTAVHYGADTVMDLSTGENLDGIRTANIDNSPVPVGTVPIYEAVTRVEDVTDITPDLLIDVVEKQAKQGVDYMTLHAGVLAEHLPLTDDRTTGIVSRGGSILSQWMTEHGEQNPLYTHYDELCEILQAHDVTISLGDGLRPGSVADASDDAQFAELDTLGELTRRAWDHGVQAMVEGPGHVPMDQIRANVDRQQEVCDGAPFYVLGPLVTDIAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGMAAYRIAAHAGDVAAGKPGARDWDDALSEARYNFDWNRQFDLALDPERAQAFHDQTLPGDNYKDARFCSMCGVDFCSMRIDQDARDAGDDADDMTELTTETDLSESAAAEVNRPPTGTHDAPAAEQAPSPGDDDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PSAA_AMBTC
Sequence: MIIRSPESEVKIMVDRDPIKTSFEEWARPGHFSRTIAKGPNTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIAPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLDAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGSTPFFTLNWSKYAEFLTFRGGLDPVTGGLWLTDIAHHHLAIAIIFLIAGHMYRTNWGIGHGLKEILEAHKGPFTGEGHKGLYEILTTSWHAQLALNLAMLGSLTIVVAHHMYSMPPYPYLAIDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHALAPGATAPGATTSTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISNQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HFQ_BACAA
Sequence: MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: MPGP_ECOLI
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLTRLREANVPVILCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQEIDGFPRIISGISHGEISLVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQFTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_HELMI
Sequence: MENIRVRFAPSPTGPLHIGGARSALFNFLLARRFGGQFIVRVEDTDLERSSRESEDNILDALEWLGITWDEGIRVGGPHAPYRQTERLHTYREAADKLLAEGKAYRCYCSEEELEAERQAFAEKGELPRYSGRCRSLSADDEARLRAEGRKPVIRFRVPDEGAVAIDDLVRGHVSFECAGIGDFIIVKSDGIPTYNFAVVIDDAQMAITHVIRGEEHLSNTPRQLLIYDALGLTPPKFAHVSLILGKDRSKMSKRHGSTSVVAYQRQGYLPEALVNFLVLLGWSPGGEEEIFSLDDLIAQFSLDRVAKSPAVFDFEKLNWINGVYLRKADLDRLVALAMPHLIEAGVVQEPLDEAAARKVRYMVQAIQEKVSYMAQIVDFIPLFFGDAITFESDEAKAVLTEEQVPKVLKACLRKLTEGRDLTPDNVKAMLKEVTKETKEKGRNVFMPIRVALTGQQHGPDLNALITALGREGAVNRIRRAAELAGVALGSSPFSC
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGDS_BOVIN
Sequence: MSVAGRAESLGPPDSFAKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYVSTDEVYGGSLDKEFDESSPKQPTNPYASSKAAAECFVQSYWEQYKFPVVITRSSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGTGLQTRNFLYATDVVEAFLTVLKKGKPGEIYNIGTNFEMSVLQLAKELIQLIKETNSESEMENWVDYVDDRPTNDMRYPMKSEKIHGLGWRPKVPWKEGIKKTIEWYRENFHNWKNAEKALEPFPVQPPFV
What are the official names of this protein?
dTDP-D-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: PXPA_RALPJ
Sequence: MTAIDLNADLGEGCDTDEALLALVSSANIACGWHAGDVNTMRQTVGWALRQGVSIGAHPSFPDRENFGRTEMHLQPDEIYAGVLFQIGGLSAIVRAQGGKLAHVKAHGALYNQASRDRPLAMAIVHAIRDFDPSLVVFGLAGGELVKAARELGLQAKEEVFADRGYNADGSLVKRGTPGALIDSEDAALDQTLTMVREQRVKAIDGTWVPIRAETVCLHGDGAHALAFARRIRERLGSEGIAVRAGA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: GLMM_FRAT1
Sequence: MAKYFGTDGIRGEVANSTITVEFTQKLGNAVGSLINQKNYPKFVIVGQDTRSSGGFLKFALVSGLNAAGIDVLDLGVVPTPVVAFMTVKHRAAAGFVITASHNKFTDNGIKLFSSNGFKLDDALEEEVEDMIDGDFIYQPQFKFGSYKILANAIDEYIESIYSRFAKFVNYKGKVVVDCAHGAASHNFEALLDKFGINYVSIASNPDGLNINVGCGATCVSNIKKAVKEQKADLGISLDGDADRIIIVDENGQEIDGDGILNILAQYSDICGGTNGIVGTQMTNMSYENHYRANKIPFIRSKVGDRYVLEDLVKYGYKIGGESSGHVINLNFGTTGDGLFTAIQLLAIFSQADKPVSEFKLQGELMQQTLINVPLTKKVAREDLQKVASDVNDVEKRLGNRGRVLLRPSGTEPVLRVMVEADDKSLATNEAEYLVEKVKQKLV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RPOB_PETMO
Sequence: MNTVVREVGRRERKFFGKVPEKTEIYEDLVKIQKDSFRDFLDKKIMESIKRYMPIKIPVKASGKKNKEFLIDFVDVKFEDSSFSENECRDKGLTYAGKAYLKVRITDSATGEMIEKDDIFLCNIPYMTERGIFIVNGAERVIVNQLVRSPGVYFIKEEETDTSKEMFIAHFLPIKGAWLEILYNPNPGKEVLQVRIDRKRKFNFFLFLRALGYENDLDILRLFPKEIDLDDEVELSNYNNCTVLSDLSFQELDDMDPPRKSTYGMKLYEVLELLKKYEIKSVTVAHLVAEITLEKMKKRYEKEERLTSLEAYKEIFSKLKPTEIPRAQKAKEEIEDMYFNPEKFDFSQIGRQKIQVKLRKAYIDYLREVEKKDISEDMEDKIKYPIKTFAVDKLDIILSARYLLHVKENIEGLDTRDHLGNKRVRSVGELMQIEFERAFSKMIQHAPEKLAGVQSINKISPQSLINSRSIMTAFHQFFASSQLSQFLDQVNPLAELTHKRRLSAIGPGGLKREHAKFEVRDVHHSHYGRMCPIETPEGANIGLITSMAILAKVDEYGFLKTPYYRVKHAKVDLNNIVYLSADEEELYRIAPASAEIGEDGSLVEEYIEARYLGKVSLFHKDEIEYISVTPKQIASVSAALIPFLEHDDANRALMGSNMQRQAVPLLRPQAPFVGTGVEWLAARDSGYLIMAKHKGIVDYVDGRKIVITRLDEENNVLKDSNDEPLKDEYTLLKYVRSNQDMCINQVPIVNVGDVVTKGQAIADGPSMDMGELALGRNIFIGFLPWEGYNFEDAIVVSQELLENDAFTSIHIEVFETKAMDTQLGPEEITADIPNVKKELLRNLDEEGIVKIGSYVSSGDILVGKVTPRGESDTTPEEKLIKSVFGDKGRDIKDSSLTVPHGIEGRVIDVQIFDRKDIPSLEIGVNKYVKVFIATKKTLQVGDKLAGRHGNKGVISTILNKEDMPFLPDGTPLQMLLSPLGVPSRMNIGQVLELHLGWLSMLTNDYYATPIFDGATESEIMDELSKVREEHELYLGDDPDQPNGKIVLRDGRTGEPFDFPVAVGSMYMLKLSHIAKDKIHARSTGPYSLIHQQPLGGKAHFGGQRFGEMEVWALEAHGAAHTLNEMLTYKSDDIKGRNEVYKAILKGENLPEPGIPESFKVLTKELQGLMLDIKLYDEDGNELDVDRL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: YFHA_KLEOX
Sequence: RMAGRNRTEFYKLLSRHELDANDFKE
What is the function of this protein?
Probable member of a two-component regulatory system YfhA/YfhK.
What are the official names of this protein?
Uncharacterized protein in glnB 5'region.
Protein: APOE_OVIMU
Sequence: MKVLWVALVVALLAGCQADMEGELGSEEPLPPEQPRGQDSQPWEQVLGRLWDYLRWVQTLSDQVQEELLNTQVIQELTVLMEETMKEVKAYREELEGQLAPMAQETQARVSKELQAAQARLGSDMEDLRNRLAQYRSEVQAMLGQSTEELRARMASHLRKLRKRLLRDADDLKKRLAVYQAGASEGAERSVSAIRERLRPLVEQSQSRAATLSTQVGQPLLDRAEAWRQKLHGRLEEVGVRAQDRLDKMRQQLEEVRAKVEEQGSQIRLQAEAFQARLRSWFEPLVEDMQRQWAGLVEKVQLALHLSPTSPPSENH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.