PharMolix/UniProtQA huggingface dataset:
Protein: GLND_RHITR
Sequence: METHHIDFSTVLDVSALKAECEALAKRGLDKNEERSALLALLKKASQDGREEARRLLIADGSGLNCAHRISWLQDQIITVLYDLTVHHAYPKQAGVFSVTAVGGYGRDTLAPGSDIDLLFLFQPKPASETHKAVEFILYMLWDMGFKVGHATRSVEECIREAKSDMTVRTAILETRYICGNVALERELQARFDKEIVTNTGPEFIAAKLAERDERHRKAGDTRYLVEPNVKEGKGGLRDLHTLFWISKYYYHVRDPAELVKLGVLSKQEYRLFEKAEDFLWAVRCHMHFLTGKAEERLSFDIQRDIAAALDYNARPGLSAVERFMKHYFLVAKDVGDLTRILCAALEDQQAKATPGLTGVISRFANRSRKIPGTVEFVEDRGRIALANPDVFKRDPVSLIRLFFVADINGLEFHPDALKRVTRSLSLIDNDLRENEEANRLFLSILTSKRDPALILRRMNEAGVLGRFIPEFGKIVSMMQFNMYHHYTVDEHLIRAVEVLSEIDKGRAEDIHPLTNKLMPNIEDRDALYVAVLLHDIAKGREEDHSEAGAAVARKLCPRFGLSPKQTELVVWLIAEHLTMSMVAQTRDLTDRKTIIDFADRVQSLDRLKMLLILTVCDIRAVGPGVWNGWKGQLLRTLYYETELLLSGGFSEVSRKERAEAAAEALEHALADWSQKERKAYVKLHYQPYLLSVPLEDQIRHTQFMRESDKAGKVLATMVRTDSFHAITEITVLSPDHPRLLTVIAGACAAAGANIADAQIFTTSDGRALDTIHVSREFPDDADELRRAATIGKMIEDVLAGRKRLPEVIATRTKNRRKNKAFVIPPSVIITNSLSNKFTVIEVECLDRPGLLSEITAVLSDLSLDIQSARITTFGEKVIDTFYVADLVGQKISNENRRAYITARLKAVMAGEEDEMRERMPSGIIAPAATRGVAVEKSDTEKKAGSAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: SSRP_ECOSE
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y3193_MYCTU
Sequence: MGMRSAARMPKLTRRSRILIMIALGVIVLLLAGPRLIDAYVDWLWFGELGYRSVFTTMLATRIVVCLVAGVVVGGIVFGGLALAYRTRPVFVPDADNDPVARYRAVVLARLRLVGIGIPAAIGLLAGIVAQSYWARIQLFLHGGDFGVRDPQFGRDLGFYAFELPFYRLMLSYMLVSVFLAFVANLVAHYIFGGIRLSGRTGALSRSARVQLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGYTDINAVLPAKLILMAIALICAAAVFSAIALRDLRIPAIGLVLLLLSSLIVGAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYSGDSPATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFPDQLSIDRYLDRNGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYFGPVISNTSADYAIVGRNGDDREYDYETNIDTKRYTYTGSGGVPLGGWLARSVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYPAIVNKRLVWIVDGYTTLDNYPYSELTSLSSATADSNEVAFNRLVPDKKVSYIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMQVFPGTVKPKSDIAPELAEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQPPYYIVAKNIAKDDNSASYQLISAMNRFKRDYLAAYISASSDPATYGNLTVLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVARGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKVGYGPTVRDALTGLFGPGAGATATGIAPTEAAVPPSPAANPPPPASGPQPPPVTAAPPVPVGAVTLSPAKVAALQEIQAAIGAARDAQKKGDFAAYGSALQRLDEAITKFNDAG
What are the official names of this protein?
UPF0182 protein Rv3193c.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZNUC_PSYCK
Sequence: MNNTSKLLNLSNVSYYIGQQRLLSNINIDIAVNETVSVIGPNGAGKSTLVKLILGLIVPTSGQVTPSEPLQIGYVPQRFSVPPILPLRVSDLLAQACKKRLTAEQRQFIFDKLSLTHLLSRQMLHLSGGETQRVLLARALLDKPNLLILDEPMQGLDPETEVWLYQFIDELPEFLRCAMLVVSHDLHWVMKGSRRVICLNKHICCEGQPSELAISSEFQKLFGHHYEQPYVHQPHACEHHAPS
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS18_GEODF
Sequence: MSDERAPQRSTGPRKKRPFQRRKVCRFCADKQVTIDYKDPRTLRYFISERGKIIPRRISGNCAKHQREITEAIKRARNIALLPIAGSHAAQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PANC_BURTA
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQEDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIVAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLARVRDAVLDGERDLAAIERRAVAHLSARGWQPDYVSIRRRENLVAPSAAQIEAGDPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_NATTJ
Sequence: MNQRGEAPISVIKRLPVYLRVLDNLVKRDIEVVSSKSLSKETGFTAEQIRKDLAFFGAFGTRGTGYNTNYLRERVLRIIGLDKQTNVAIVGAGHLGTAFARYNVRENPYTSVVGLFDVSPDIVGENIEGVPVYHLNDLQEIVRKERVQVGVITVPAVHAQEVVDRLVEENVKALLNFAPAKLTAPEDVRIHNVDLTIELQSLIYFAKDELNEESTQDLE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_AQUAE
Sequence: MKLGVLGSTGSVGSQTLQVYENFRDEIELVGILANRASEKLLQQAKKYKPKYVVSYQEPAKEWLESLPEGVKYLKGDEGLKAIIEESERLMNAISGIYGIKPAYEVIKAGKTLLASNKESILCLGEIIRKNRERVIPVDSEHNALFQLLSSVKREEVKHVYLTASGGPFKDKSLEELKTASVEEALRHPRWNMGAKITIDSATLMNKGFEMLEAHFLFDFPIENIKVVIHPQSFVHGILELIDNSFLMHTSQTDMKIPIMHALFYPKRKEYPFKKVSLLELSPITFEKVDTTKFKAIDLAKWAGFMGGVYIPVLVGADEEAVNLFLNKKIGFLDIVDLIEQALSEVNIKDPQSVEEILEAVEWGRQKVREIYERKYAGKG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TBP2_ENTH1
Sequence: MSQLGNICHADYMSTSTESQERSLNNPNDTHPEIVNVVSTFQLGVKLELRKIVQKARNAEYNPKRFAGAIMRISSPKSTALIFQTGKIVCTGTRSIEESKIASKKYAKIIKKIGYPIHYSNFNVQNIVGSCDVKFQIALRTLVDSYLAFCQYEPEVFPGLVYRMASPKVTLLVFSTGKVVLTGAKDEESLNLAYKNIYPILLANRKEDISNQ
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein 2, EhTBP2, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: RGS20_BOVIN
Sequence: MPRLSQDNQQGHQKHFSRPSRRIQFLPPPWTEAYNVNVHQTVENEGCATAMHNVKLLGSPAAPTLLSLLSGTLSGFARFFALLLRRPPPEAPLRRRDFSALIPALPAAVLSPGHEERPGRLSLLLRAALALPGRPPGGRLPREVDASAGQSSSIPPMGSEWMEMRKRPVCAAQEPTACAPGQPGVENQGSNACCFCWCCCCSCSCLTVRNQEEQRLRRTSYEARTEDLPTCEESPGPTLEEASAWAQSFDKLMLTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKATIEEKARIIYEDYISILSPKEVSLDSRVRETINRSMAEPSRNIFDDAQLQIYTLMHRDSYPRFMNSALYKDLLRSLSEKAVEA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities.  The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein.  Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 20, RGS20, Retina-specific regulator of G-protein signaling 1, Ret-RGS1.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation.
Protein: ALLC_MOUSE
Sequence: MTDTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSDSPTFKEHEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQGIIRGIDVDISYFSGNHAPRMSIQAANLSEEDTMSNIPPRGVRMGTAATPEEFEAVTELKSHSWDYLVPMSELKLGDPDSSHNYYFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGEPKSIADGWETARRLDRPPVLEASENGLLLVPGCEWAVFRLAHPGVITQIEIDTKYFKGNCPNSCKVDGCILTTLEEEDMIRHNWNLPAHKWKSLLPVTKLIPNQNHLLDSLTLELQDVITHAMITIAPDGGVSRLRLKGFPSSICLLRPLREKPLLRFSLKTGFRANL
What is the function of this protein?
The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.
What are the official names of this protein?
Probable inactive allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: TAF7L_MOUSE
Sequence: MERGEEAPTEGAPPEGALVEAKAPVIPEAPATDVSTTEEAGSKEPQVPSGPRPEGAGDTCDTRGARGPPTPGRAKSQKTPRQGTARCQTLESAMRSMSVRLECHDVEEQFILRLPPEQAYAVRKIIHSRNAAWKDKLKIDFSPDGHHAVVQVDNVSLPAKLVNLPCVIGSLKTIDRKTFYKTADVSQMLVCSPEGEPHSPPEEPVVSTGPTVIGISEGKAERKKYNWKHGITPPLKNVRKKRFRKTTKKLPDVKQVDEINFSEYTQSPSVEKEVKRLLYSDAEAVSVRWEVVDDDDAKEIESQGSMPTTPGISQMGGASLSDYDVFREMMGDSGSNSNDVEEKSNEGDDDDDEDEDDEDYGNEKEEEETDNSEEELEKELQAKFNEFSLHEADQDYSSITMAIQKLIFIKEKRLQMIYKKAQRQKELLRKVENLTLKRHFQNVLGKLNIMEKEKCEQIYHLQEQLKCFLKE
What is the function of this protein?
Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.  May play a role in spermatogenesis.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 7-like, TATA box binding protein-associated factor RNA polymerase II subunit Q, TATA box-binding protein-associated factor 50 kDa, Transcription initiation factor TFIID 50 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TAF7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
Protein: SLAA_MACLB
Sequence: MGRSISVSFGLLVVFLSLSGIGADFDCPSGWSAYDQHCYQAVDEPKSWADAEKFCTEQANGGHLVSIDSKKEANFVAELVSQNIKETRRTDFVWIGLRAEDKRQHCSSEWSDGSSINYQNWIEAESKKCLGLEKQTRYRKWVNLNCGQPYRFTCEI
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec A10, C-type lectin A10.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAA_ECOL6
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: YCPW_PSETP
Sequence: MSDPKESAAVASLYNTYPFPPEPILDEPPPGYNWRWNWQAAYSFCTGQKPSRDNIRILDAGCGSGVSTEYLVHLNPEATVVGIDLSEGTLAVAKERCQRSEQLEPN
What are the official names of this protein?
Uncharacterized phycocyanin operon protein W, ORF W.
Protein: SEY1_KOMPG
Sequence: MTDLEVSAIQVIDENKVFNSLLVDYMKQFYSQNNSSDDKGLNYHIVSVFGSQSTGKSTLLNHLFHTKFDVMDESQRQQTTKGIWLAHANHISSSNESGDFANNTKNVFVMDVEGTDGRERGEDQDFERKAALFALSTSEILIINIWEHQVGLYQGANLGLLRTVFEVNLSLFAKNKQRCLLLFVIRDHVGNTSLESLSDVLTLDLQNIWSQLNKPQGTEGFELDDFFDLKFVALAHKLLQPDKFIEDISVLGDKFISEDQLFNEGYHRAIPIDGWSMYAEQVWEQIETNQDLDLPTQQILVARFRCDEISSQVYESFHEQFVKSNWDDLSFTEIGNSLKELRQNAVQQYDILAGRYSESVYLQRKKLLVQKVDLSILEVYTSVLQKLIRQSRDLYLKQIESSLTKKEAGIIFYQVLDNAERESLKYFNENTSLISFVDVDDSEARSYDPSPKLRELEEELSNLRTELVNKEQENIKTKIPRKFKSHFKLIVQDELSNIKPSSWEELLDQFRQVSEKLLAKYKSPDSNYDFHLGLSKEKNKELHEQVLIKFWIKFKEILNDFVTETNVLRLLVSKFEDEFRYDEEGLPVVWKNSAEIDVKFAKARNSALDLLPLFSLAHTAEGEILPDYDIAHDEAEAESDNEEDDGFKESHKFAHLLSARDQDAIRNKFKKQTDALYVETKRSVINSKTEVPLYIYALLLVLGWNEFMIILRNPLLITLLLIGLTGLYLGYKTKLLGPIVQVVQAMIQELQDQAKNKLRDVLVSEPEAPSQVRIGKEVDATKDED
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: CAND1_DICDI
Sequence: MSFFLGQILEKMGSIDKDIRFMATHDLANELEKDTFKMDPTYENKIVTKLLALTADSANNVQENVVKCLGLLIKRVKDSQATEIIDTLSKNILEESNKEELVEISGIGLKTIITNLPSEGSSISTLVIKNLVPKLLIGIDSEKLKDKNEIKMSCLDILNDLLQKYGSFMIGDLENIQKVVLPKLNATRPAIRKRAILCLANIAFPSPDNLFNSLLDYIIKSIEEAKKPDHISTLIQAIGAICKSSGYRLGKYLPKVMPHVLNYCDNNKFEQNDELRENCLLCFEAIIEKCQKDVTPYIGEIITLCTKYIKFDPNYSDDGEGEEDGDEEEEEMETSGDNDEEQEEEEEEEDLSDDDDISWKIRRSSCKTLCAIISTRPELLVELYQKVAPVLYNRFKEREENVRLDIFTTFVLLLKQLNKKLANPQAKEVLKQQVPKLVQSISKSLIDKSIRTRVGAIALLKELVMIIPGSLTGQVSQIVNGINLSLSEKNTNSNLKIEALVLLKLLLINEPAQSFQSHITSLSTHIVKCINDSYYRIASEALRVCQEFVIVFNKIRSSTDCKPIISNLFAANFVQLKAQDIDQEVKEAAISSIGTIITLFGNEIQSELQPCLSILLERLDNELTRVVTVKVLSRIINSSINIDLSSILPSAIKLLSTFLRKNNRVLKQSSLIALNDIVKVCPNLLPSSLLTGILTEMATLINESDLQITHLAFVFIQNLLKNYSEKHQAATLVNEKCIPPTLALLKSSLLQGVALESLLSLFATIVQLDEPGMKYEQLLTLLFNTAADIKQPVTRQSFHSISQCIAVITVNTTPALRKQTIHNLICNLSSVNEPLVLLSLSCLGEIGRRIDIHENENLQESVYKTFEANNEEIKQVAALCLGDIAVCSLQSYLPFILEQIKNQPKKQYLLLHTLRETIVKLSHTDEGIKTIHPFLQSILPLLFDNCVNEEEGTRNIVAECLGKLSMIEPNEIIPKLVEKIKSPSPLERSTIVTSIKFSIMENKEVVDQYLAPNISQFLSLLHDGDLIVRRSALLSLNYIAHNKPNLIRNDLSVYLPILYNNAKIKPELIREVDLGPFKHKVDDGIEIRKTAFECMYTLLDTSIDKIDVAPFIVSLCDGLKDTQYDIKLLCHLMIIRLANSNGAALLENITLLLEPLRVILMTKVNETAVKQQIERNEECIRSALRAVASISRIPNSDSIVKFEEFVKNTIRTTPLAAQFNSILSEDTMSNQDSMDTSN
What is the function of this protein?
Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.  Acts as a F-box protein exchange factor (By similarity).
What are the official names of this protein?
Cullin-associated NEDD8-dissociated protein 1, Cullin-associated and neddylation-dissociated protein 1.
What is the protein family that this protein belongs to?
Belongs to the CAND family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PMIP1_CRYNJ
Sequence: MLRLPRITRRALSSGALAPHFDRPLPPPPPAPPAPLCALPPLTAPDALAPLTRRTVRHADALVARIAAAPAHPDPAELRRVVKNLDRLSDVLCGVIDMCELVRNVHPDPRWVAAAEKTYETLCSFMNQLNTSTGLYDALVATVSHTFPGNPLSPAELRVAQTFLSDFERSGIQLPPGVRAKFVRHSDNILSLGRTFLSFAAAGPSADTPIEIPEPEVLLAGLSSKFVASLPRKKRKGPALLAPGSWEAQMIGRYADNEEARRLVYIGSMREDKDRVYVLETMLKERAELAHVLGKETWADVALSDKMAKTPQNVLQFLTSLATHHRPSAAADVAALQRLKALSTVSRTSSQLPTVHAWDRDHYAEQYAASLLPNGSLPSITPYFSVGTAMSGLSHMLSRLYGISFKPVSVAHGEVWHPSVRRLDVMDEHGKRIGVIYCDLFSRPGKPSAGAAHYTVRCSRRVDDDPSEGDGLPPGWDQHLGKGMEVQGEALHGKEGKYQLPIVVLTTDFGTVEESGPALLGWNDLETLFHEMGHAIHSMIGQTEFHNVSGTRCATDFVELPSILMEHFISSPAVLSTFATHYTTNEPLPIPLIQAHLQLDQSLKALETHSQILMALLDQKYHSIKHGEQLDSTRVWNELQSQVGVIPPVRGTAWQTQFGHLYGYGATYYSYLFDRAIAGKIWSSLFARGRTGPAAANHDPAAAEDILSREGGEAFKEKVLKWGGGRDPWEMVGDVIGGAEGEQVAKGDEKAMELVGRWMIK
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase 1, MIP 1, Octapeptidyl aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AROC_BURO0
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMGLTEADIQIELDRRKPGTSRHVTQRQEADEVEILSGVFEGVTTGTPIALLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPIVGAGAVAKKWLRERFGVEVRGYMSGLGEIDVPFVDWSYVHENPFFSPNAAVVPELEAYMDALRNDGDSIGARIDVVASGVPVGWGEPVFDRLDADIAKAMMSINAVKGVEIGAGFDSVAQRGSVHGDELTPAGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITKSGDEATVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVETSTPKIAGSAT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CIA2B_DICDI
Sequence: MSDNPNPVIYVDNENCKSFEDNENSFNSSRYSIEEDQIDEFDEQEIFDLVRSITDPEHPLTLEQLNVVRIENVNINLENSYILLYFTPTVPHCSMANLIGLSIKEKLARSLPKRFKVDVIVTPGSHSSESSVNKQLNDKERVSAALDTSSSILTIVNECIKQN
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.  May play a role in chromosome segregation through establishment of sister chromatid cohesion.
What are the official names of this protein?
Cytosolic iron-sulfur assembly component 2B.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: CRML_HUMAN
Sequence: MTVKLGDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTEDKNTFFEGLYEHGKDFEAIQNNIALKYKKKGKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKSSQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKLCDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIEFLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKAFCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNSRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGGGPAVSDLSQ
What are the official names of this protein?
Protein cramped-like, Cramped chromatin regulator homolog 1, Hematological and neurological expressed 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the cramped family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HS74L_MESAU
Sequence: SVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRSQIVTNVRNTIHGFKKIRLPYELQKMPNGSTGVKVRLKVLATTFDPYLGGRVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARNHPAPFSKSIDLPIQSSLYRNAVEEYVYDFRDKFITPEDMNKYGQPIQMKYVEHEERPK
What is the function of this protein?
Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.
What are the official names of this protein?
Heat shock 70 kDa protein 4L, Heat shock 70-related protein APG-1, Osmotic stress protein 94.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May translocate to the nucleus after heat shock.
Protein: DNAK_LACPL
Sequence: MASNKIIGIDLGTTNSAVAVLEGNEPKIITTPEGGRTVPSVVAFKDGETQVGEVAKRQAITNPNTVASIKRHMGEAGYKVSIEGKDYTPQQISAMILQYIKGFAEDYLGDTVEKAVVTVPAYFNDAQRQATKDAGKIAGLNIERIINEPTAAALAYGLDKTDKDEKILVYDLGGGTFDVSILELGDGVFEVLSTNGDTHLGGDDFDQKIIDWLVDGFKADNGVDLSKDKMALQRLKDAAEKAKKDLSGVSEAQISLPFISAGASGPLHLETTLTRAKFNELTADLVEKTRIPVENALKDADLSASDLDVVILNGGSTRIPAVQEAVEKWTGKESNHSINPDEAVALGAAVQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGVPQIEVKFDIDKNGIVNVSAKDMGTNKEQKITIKSSSGLSDDEIDQMVKEAKENEEADKKRKEEVDLKNEVDQLIFTTDKTLKDLEGKVSEDEVKKAKDARDALKKAQDDNNIDEMKAKKDDLNKIVQDLSVKLYQQAQEAQGAQGGADSNAAGNANSAKGSDDNTVDGDFEDLDKDKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.