PharMolix/UniProtQA huggingface dataset:
Protein: LOLA_SHEPC
Sequence: MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGILALAHPNQFYWHLTSPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDTTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTKFNVLDDKGNISQFDLSNQKVITTEDKALFKFVLPENVDIDDQRLKTLN
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLMU_CHESB
Sequence: MTNRTCLAVILAAGEGTRMKSTLPKVLHKIGGLEMVGHVMNAASSAGADALALVVGNGAEQVRAFAEKQTADRRDIFVQEERLGTAHAVLAAREAMSRGYDDVLVVFGDHPLLDPSVLLSAREKLAEGAAVAVLGFRPPVPTGYGRLIEKEGRLVAIREEKDCSEEERKITFCNSGVMAIAGKHALALIDQVKNENAKGEYYLTDIVEIANRQGLLVVASEAGRESAVGINNRAELAEAEAVWQQKRRRELMLSGVTLIAPETVFLSYDTQIGPDTVIEPNVWFGPGVRIASGAHIHAFSHIEEAVVETGATVGPFARLRPGAQVQEKAKIGNFCEIKNARIEPGAKVPHLSYIGDATVGAGANIGAGTITCNYDGFLKHHTEIGAGAFIGTNSALVAPVTIGAGAYVASGSVLTEDVPADALAFGRARQATYEGRGKVLRDKLAEEKAKKSGG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBX_CROS5
Sequence: MTPSLANFLWSLVWGTVIVVIPVTVGLVFISQSDKIKRNF
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: EFP_SYNAS
Sequence: MYSASDLRKNLRIKLEGDPYIITEFNFVKPGKGQALYRCKLKNMITGNQFERTFRSVDNFEAADLQEKKMQFLYTEEDRYCFMDNTSYEQIFLTADQVGDAAHFLIDNLEVEILLFEDKPLGISLPNFVDLVVTKADPWAKGDTVSGNTKPVTLQTGYQIMVPPFIEEGEKIRVDTRTGEYLTRVKG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLC_PHOPR
Sequence: MTKIALQQDRPLDAIVLGRAGVDLYAREANTDMADISGFNKFVGGSAANIAVAISKLGGKVGFIGCVADDAFGGYVRGYMTEQGINLDGMMTDNSGSRTSVAFTEMKPNDCTVLIYRNKASDLTLKPEQVDPAYIAQSKMLVVTGTALSESPSREATLIAMEHARRSNTVVVLDVDYRPYSWRTDVDASIYYGIAAGLSDIVIGNREEFDMMETVLAPGNTDDDATADRFLRANTQVVIVKAGELGSKVYCKDGHKFQQGIFRVEVKKPFGSGDSFAGGLIWTLVNGGELEDGVKHGSAAAAINVSGNSCTEAMPTKEVLFDFIETREQDL
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: NPD_LISMF
Sequence: MNKLNEALKKAEHIVFLTGAGVSVPSGIPDYRSKNGLYAGMSSPEYMLSHTCLVREPEKFYQFVTENMYYPDAEPNAIHTKMAEIEAEKDVTIITQNIDGLHEKAGSKKVVNFHGSLYHCYCQKCGMSVTAEEYLKSDIHSGCGGVIRPDVVLYEEAIPESAIDQSLAAIRQADLIVIVGTSFRVSPFCNLTDYRNKKARIFAVNKEQISLPYPFEMMESDAVKVFAEI
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_PROMH
Sequence: MNQTLLSEFGSPLERVERALEALRAGKGVMVLDDENRENEGDMVFVAETMTTEQMAMSIRHGSGIVCVCITEERRQQLDLPMMVENNTSHFHTAFTVTIEAAQGVTTGVSAADRLTTVRAAAADNAKPSDLNRPGHVFPLRAQPGGVLTRGGHTEASIDLATLAGFKPVAVLCELTNDDGTMARAPEVVTFAKQHDMPVLTIEDLVAYRLREEKKAG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: V009_FOWPN
Sequence: MNKALMIFVYYLTRVTLSKCLVYFTKERYVLKKIDTPIGIPNTCVRFTTSFLYNSILYVLVNRKSV
What are the official names of this protein?
Uncharacterized protein FPV009/FPV252, ORF b.
Protein: CISY_RICAU
Sequence: DSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYNIKDLAEKSDFLEVAYLLIYGELPTIEQYNNFTTQVAHHSLVNERLHYLFQAFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANAFACISTGIASLWGPAHGGANEAVINMLKEIGSSENIPKFIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKAVLKELGQLENNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: ITGBL_RAT
Sequence: MHPPGFKNFLLLVSSLFFIGLSAAPQSFSPSLRSLSGAPCRLSRAESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGPLCECHDWVCETYDGKTCAGHGTCDCGKCKCDVGWSGEACQYPTKCDLTKKISNQMCKNSQDVICSNAGTCHCGRCKCDNSDGHGLIYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCEAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCRAGWYGKKCEHPKNCPLSAEESTRKCQGSSDLPCSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGRGTCSCGRCVCEKGWFGKLCQHPRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP
What are the official names of this protein?
Integrin beta-like protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: RPC8_YEAST
Sequence: MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA.  The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC8, RNA polymerase III subunit C8, DNA-directed RNA polymerase III 25 kDa polypeptide, RNA polymerase III subunit C25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMKL_PHOLL
Sequence: MNSLFASTARGLEELLKNELEMLGAQSCKIVQGGVHFQGDGRVMYKSLMWSRLASRILLPLNEFNVYSDLDLYLGVQSIDWSQVFSVHSTFSVHFSGTNEEIRNTQYGALKVKDAIVDSFTRKLDQRPNVAKQQPDVRINVFLNKEKASVALDLSGDGLHIRGYRDLAGQAPLKENLAAAIVQRSGWQIGTPMVDPMCGSGTLLIEAAMMAADRAPGLHRDHWGFTAWLKHDEAIWREVITEAQIRFRKGLQETTCRFVGSDIDRRVLDMARSNARRAGVAQLITFQQGDASRLENPLPEGPAGTVLSNPPYGERLESEPALIALHSLFGRIMKSRFPSWRLSLFSASPELLSCLQLRAEREFKAKNGPLDCVQKNYLLSDKPHSSEVNVAEDYANRLRKNEKKLAHWAKQQGIDCYRLYDADLPEYNVAVDRYADKVVIQEYAPPKSVDANKARQRLFDVISATMQVLGLSSNQLVLKTRQRQKGKSQYERMAEKQEFFLVNEYDAKFWVNLTDYLDTGLFLDHRIARKMLGEMSEGKDFLNLFAYTGAATVHAGLGGARSTTTVDMSRTYLEWAERNLQANELTGRQHRLIQADCLAWLARANEQFDLIFIDPPTFSNSKRMEDTFDVQRDHIMLMRQLKRLLRRGGTLMFSNNKRGFKMDFAELEKVGLVAEEITSKTQSQDFARNRQIHNCWLLRHAGEEK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y723_TREPA
Sequence: MMVHFRFPFPGGEFPVSAQPEFELVARLHAAVVREEDVWQKRTP
What are the official names of this protein?
Uncharacterized protein TP_0723.
Protein: LIS1_AJEDR
Sequence: MSQLLTPRQAEELHKSIIAYFLSAKLPKSAAALREEIADSVQLDDSTAKKYEGLLEKKWTSVVRLQKKIMDLEARNSALQSELDSATPTSLSRRNQDPVSWLPRAPARHRLESHRNPVTSVAFHPVFSSLASGSEDTTIKIWDWELGELERTIKGHTRAVVDVDYGGPHGGTLLASCSSDLTIKLWDPSDEYKNIRTLPGHDHSVSAVRFIPSGAAGSPLSGNLLVSASRDKTLRIWDVTTGYCVRTLHGHVEWVRDVVPSPDGRFLFSAGDDRVARLWDVSSGETKSTFLGHEHFIECVALAPPTTYPYLAALAGLKKPPPPSSSAEYVATGSRDKTIRVWDSRGTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDLSQEFKCVRVVTDAHAFVTCIRWAPNIIKDAGGMGVNGDINGGGSLALSGVNGIIPGSKKEDPGGGAKLGIRCVIATGSVDLNVRVFAS
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: POTA_BORBU
Sequence: MDNCILEIKNLSHYYDNNGNKTLDNINLKIKKNEFITLLGPSGCGKTTLIKILGGFLSQKNGEIYFFSKEISKTSPNKREINTVFQNYALFPHMNVFDNISFGLRMKKTPKDIIKEKVKTSLSLIGMPKYAYRNINELSGGQKQRVAIARAMVMEPKLLLLDEPLSALDLKMRQEMQKELKKIQRQLGITFIYVTHDQEEALTMSDRIVVMNEGIILQIGTPEEIYNEPKTKFVADFIGESNIFDGTYKKELVVSLLGHEFECLDKGFEAEEAVDLVIRPEDVKLLPKGKGHLSGTITSAIFQGVHYEMTLEIQKTNWIVQSTRLTKVGEEVDIFLEPDDIHVMHKE
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BTUB_YERPA
Sequence: MTIKKYTLLTALSVTAFSGWAQGNNTTDNNDEMVVTANRFPQPKSSVLAPVDVVTRADIDRWQSTNINDVLRRLPGVDIAQDGGMGQRSSLFIRGTNSSHVLVLIDGVRLNQAGITGASDLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVINILTGRDKPGTTLSAGLGSNGYQTYDGSTQQKLGEDTTVTLAGNYTYSKGYDVVAGMPGAGGPRQPDRDGFMGKMLWAGLEHQFNEQFNGFARVYGFDNRSDYDGYTNYSNPLALIDTRKLSSRTYDTGLRYKNGIYASQFIASYNRTKDYNYSPLFGQHDITASLDEAEQYNLQWGNTFQLTNGMISAGADWQEQRTERKSSNQNTTADFTQHNTGIYLTGQQQISDVTLEGAVRSDDNSQFGWHSTWQTSAGWEFIDGYRLIGSYGTAYKAPNLMQLYSAYGGNANLKPEESKQWEGGVEGLTGPLTWRLSAYRNDIDQLIDYSNLTNGYFNINKATIKGVEWTGSFDTGPLSHQVTLEYLDPRNADTHEILVRRAKQQVKYQLDWQVADLDWSVTYQYLGQRYDKDYSTYPEETVELGGVSLWDLAVSYPVTSHLTVRGRIANLFDKDYEMVYGYQTPGREYYFTGSYNF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y1474_STRP4
Sequence: MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLESFYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHVFITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSSEFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLSQPQGLVFVKEV
What are the official names of this protein?
UPF0246 protein SPG_1474.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: MANA_NEOFI
Sequence: MKFSFLTVASFLIGQVALAALSAKKFASASDLQFTIDGKTGYFAGSNSYWIGFLTNNADVDLVFDHMKESGLKILRVWGFNDVNTVPGQGTVYYQVHANGKSTINTGADGLQRLDYVVHSAEKRGIKLIINFVNNWDDYGGMNAYVKAYGETDHNAFYSNKNIQNAYRRYVKAVVSRYTNSPAVFAWELANEPRCKGCDTEVLYEWIKSTSEYIKKLDKRHMVCIGDEGFGLDLLSDGSYPYTYVEGSNFTRNLAIPTIDFGTFHLYPDSWGTTHEWGNGWAQSHGAACKAAGKPCLFEEYGVTSNHCALETPWQKTSLNTTGVSGDLYWQYGDTLSTGQSPNDGNTIYYGTDEFKCIVKDHVAAIKAKQGWV
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase A, Endo-beta-1,4-mannanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSK_VIBPA
Sequence: MFKENAKKVETIIKTSEEPQSSRLNGFQRLKECCFIVGVLSSVLLAVALFTFSPADPSWSQTAWGGEIDNAGGLFGAWLADTLFFTFGSLAYPIPFLLAAAAWVICRKRGEDEPIDFMLWGTRLLGLTVLIMTSCGLADINFDDIWYFSSGGVVGDVLSSLALPTLNVLGTTLVLLFLWGAGFTLFTGISWLNIVEWLGDRSLAVLAAIANKFRGSEQETLEPQLDEFVEDKVSTKHVEDDQQDDETLPHLTAYEVEEPKEKAAVHEYPIYMPQAKSETSAVKPTPEPQPQRVAAVNATPTYVEPEPQLKAVSTDNVDPMVERTKQLNVTIEELEAAAQQADDWASEEQTSQSYADTNAVYQEQVQAKHEEVVEHDTPQLESSYAEYAQFAAQQEQQLHVEPTPHEEPVIDTRALDDITDHAEPSEHIEPTISDFDVVDEEETYVAPQPQSRSPEPQPMVQPQSVSQIQPEQAPEPSVAFEPAPQEVEVEEVQDGDQDVAAFQSMVSSAQAKVAATQNPFLMKQEQNLPVPEEPLPTLELLYHPEKRENFIDREALEQVARLVESKLADYKIKADVVGIYPGPVITRFELDLAPGVKVSRISGLSMDLARALSAMAVRVVEVIPGKPYVGLELPNMSRQTVYLSDVISSPQFEQAKSPTTVVLGQDIAGEAVIADIAKMPHVLVAGTTGSGKSVGVNVMILSMLYKASPEDLRFIMIDPKMLELSIYEGIPHLLAEVVTDMKDASNALRWCVGEMERRYKLMSALGVRNVKGFNEKLKMAAEAGHPIHDPFWQEGDSMDTEPPLLEKLPYIVVVVDEFADLMMVVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFTVSTKTDSRTILDQGGAESLLGMGDMLYLPPGSSHTIRVHGAFASDDDVHAVVNNWKARGKPNYIDEIISGDQGPESLLPGEQMESDEEMDPLFDQVVEHVVQSRRGSVSGVQRRFKIGYNRAARIVEQLEAQGIVSAPGHNGNREVLAPAPPKD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: C5131_DICDI
Sequence: MNYLVGLVLIFTIFYFFLQKNDKNMNSKIPGPKGIPILGNLLSMKGDLHLKLQEWYKQYGVIYRIKMGNVETVVLTEYPIIREAFIGNSNSFVNRFQRKSRLKLNNGENLVIVNGDIHNKLKTLVLSEMTNQRIKKYETSFIDNEIKKLFKVLDEHADTGKPIILNNHIKMFSMNIVLCFTFGLNYSYPYDEFEKASEFIKLMVEFFNIAGQPIISDFIPSLEPFIDTSNYLNTYKRIFNYTSDLITKFKNENEIHNNINDNNKSLADKPILSKLLQSFENGEISWDSVVSTCIDLQTAGADTSANTILYCLLELINNPNIQSKVYDDIKQAIIQSKENENQNDNENQEQTEEIITLSFNKYRTLAPYLSMVVKETFRKYPSGTIGLPHVTSEDVELNGYKICAGTQIIQNIWATHRNEKQFSEPDSFIPERFISQQQSANSNLIHFGCGVRDCIGKSLADSEIFTMLASLINRYEFTNPNPSTPLNEIGKFGITYSCPENKIIIKKRF
What are the official names of this protein?
Probable cytochrome P450 513A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DLTC_BACC1
Sequence: MAEFKEQVLDILEEVCENDIVKENLDVQLFEEGILDSFAVVSLLVEFQERLDIEVSISDFDRDEWATPNMVIKKLEEIR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BURO1
Sequence: MAFLLHQARFYTTVNHLRDLPPTVQPEIAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVANLVDLPGYGYAEVPGAAKAHWEMLLSSYLATRSQLCGLILMMDSRRPLTDLDRRMIEWFAPTGKPIHTLLTKCDKLTRQESINALRNTQKGLDAYRDQGVKGKLTVQLFSALKRTGLDEAHELIESWLRPSVADEKSEPVAQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYK1_ECOL6
Sequence: MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAU12_ARATH
Sequence: MAVKRSSKLTQTAMLKQILKRCSSLAKNQCYDEDGLPVDVPKGHFPVYVGEKRSRYIVPISFLTHPKFKSLLQQAEEEFGFNHDMGLTIPCEEVVFRSLTSMIG
What is the function of this protein?
Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e. g.  AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (By similarity).  Triggers plant growth probably by promoting cell elongation (By similarity).  Regulates branch angles and bending (By similarity).
What are the official names of this protein?
Protein SMALL AUXIN UP-REGULATED RNA 12.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ELF4_MOUSE
Sequence: MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELVHLCSGLDLDEVHNGIIRDRTLCMTQDQILEGSILLTDDDVSTSNNVSSTEVLFNVATPSDVLDEKQIFSSPEVLSDSNSVQAINLPNFLLSTPEPDDLKKTSDAGDQKEHSEEEKVSREENLRKMGKARKRNRKTKNNRSTSPVTDPSMPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESPETPEDSSQASTSSTPSTSTIRRASSRVGTRASPEDKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPQVSTFKDTFTLQTSFPLNTNLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIGAGSAGPSSQPPGTVIAAFIRTSSGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQGHLQPLPSQVLSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSGSGPLFVTEPSVTRSPTQAPFSPFNPTSLIKMEPQDI
What is the function of this protein?
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'.  Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of LYZ.  Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity).  Transactivates the PRF1 promoter in natural killer (NK) cells and in CD8+ T cells (PubMed:34326534).  Plays a role in the development and function of NK and NK T-cells and in innate immunity.  Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2.  Controls cell senescence in a p53-dependent manner.  Can also promote cellular transformation through inhibition of the p16 pathway.  Is a transcriptional regulator of inflammation, controlling T-helper 17 (Th17) cells and macrophage inflammatory responses.  Required for sustained transcription of anti-inflammatory genes, including IL1RN (PubMed:34326534, PubMed:35266071).  Is a negative regulator of pro-inflammatory cytokines expression, including IL17A, IL1B, IL6, TNFA and CXCL1 (PubMed:34326534, PubMed:35266071).  Down-regulates expression of TREM1, a cell surface receptor involved in the amplification of inflammatory responses (PubMed:34326534, PubMed:35266071).
What are the official names of this protein?
ETS-related transcription factor Elf-4, E74-like factor 4, Myeloid Elf-1-like factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Accumulation into PML nuclear bodies is mediated by PML.
Protein: NHAA_BORPD
Sequence: MTRHHSAPRNLPRAQLYAERAFATLERFLHVEAVSGAVLLAAAAIALVWANSAFAHSYHALWHAPLSFRLGSYEFAQPLHFWINDALMTLFFLAVGMEIRREIHEGALSNFRQAALPLAAALGGVVAPALIYLAFNGQAPRSAGWAVPTATDIAFAVGVLALLGRAIPGNVRIFLLALAIIDDIIAVLIIAFFYSGGLDYSGFAVAALGIAIVLGLQRIGIGTAYAYVLPGAIVWTGLLMTGAHPTLAGVVLGLMTPVVPRRMREQPLEMMSRATRELAGWYQAQPAAESGAPTLPLRQLRVAQREILPPVVRVQAALHPWVAYAIMPLFALANAGVSLDGVDLAAGGSHWVMAGVAGALIVGKPAGVIAMSWLLVRLGWCRLPPGVTWGGIVLIGLLAGVGFTMSIFIAMLAFAGDANMLGAAKLGVLLGSLATAMLGLAWGAIYARRLRGASATRGTAQAPDSAHS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.