PharMolix/UniProtQA huggingface dataset:
Protein: RRP41_AERPE
Sequence: MAGPAQAGVELIRDGRRHDGRLPEDLRPVRMQVGILHNADGSALVEFGRTRVLAAVYGPREPHQRFYVLPDRAALRVRYHMAPFSTDERKSPAPSRREIELSKVVREALEPVVLAEEFPRTVIDVFLEVLQADGGTRTAAVTAASLALADAGIPMRALVGGVAVGKIQGVLVVDVDELEDMYGEADMPVAAAPDIGEITLLQLNGVLTGEEFRTALAMALRAIDRVVEMEKEAIRKSYLEVGGGQE
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_ALBFT
Sequence: MRGLVRLGLTGGIGSGKSTVAGLLAELGAAVVDADAIARHLTAPNGPAIASIAATFGPDFITSTGAMDREKMRALAYADITARQRLEAIIHPLVRQETQRQTLLAANQGHPCIVFDVPLLVESTTWREKLDWVLVVDCTPATQISRVMARNALTRDEVEKIIASQASRRHRLNAADAVIFNDSLSLGALALEVDEVARHFGLSCQPLSPNQK
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KR201_HUMAN
Sequence: MIYYSNYYGGYGYGGLGCGYGCGYRGYGCGYGGYGGYGNGYYCPSCYGRYWSYGFY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 20-1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 20 family.
Protein: LIMS2_HUMAN
Sequence: MTGSNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA
What is the function of this protein?
Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.  Plays a role in modulating cell spreading and migration.
What are the official names of this protein?
LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, Particularly interesting new Cys-His protein 2, PINCH-2.
What are the subcellular locations of this protein?
Nucleus. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2075_CLOBL
Sequence: MSRLSKEEISERLLELIKDETKPAIGCTEPVAVAFTVATGKKYMAGEVLKIDLKVSKNILKNGKSVTIPNTEVCGLDIAGALGGICGDPEEGLFVFKNVNKDYLDKAREMIKNKVVTLNPIENTDPVFVEATLKGEKDEVIAILEGGHTNIERIIVNGKIAFEKDNKNEKDNKDCDFMKELSLKDIREITEDISIEKLGFIMDGIEMNKEAAKEGLKRQKGLTLGSSLLKLQQEGKLGKDSATIARILTAAGSDLRMGGGMCPIMTSGGSGNQGLCVILPITVVAEDIKAPKEKLQRAVFFGHAVNNFVKKYTGKLSAICGCAIAAGIGATAGIAWLLGGKDKEINGAILNMLANLTGMVCDGAKGSCAIKLSTSASEAVISAYLALNDIIVPNNTGIIGNTVEDTINNLGMLCKDGFYKADDVMLSIACKEVI
What are the official names of this protein?
UPF0597 protein CLI_2075.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: RL32_GEOKA
Sequence: MAVPFRRTSKTRKRLRRTHFKLQVPGMVQCPNCGEWKLAHRVCKACGTYKGRDVVNK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MECA_STAAE
Sequence: MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHSNPITTEFEDLLYMVDGTYYYAVYFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: PAND_YERPG
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAIDIYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSYAAARLHHPKVAYFEGENQLQRKAKAVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL3B2_MOUSE
Sequence: MDQQMALTWGLCYMALVALCWGHEVTEEEETVPLKTLECYNDYTNRIICSWADTEDAQGLINMTLLYHQLDKIQSVSCELSEKLMWSECPSSHRCVPRRCVIPYTRFSNGDNDYYSFQPDRDLGIQLMVPLAQHVQPPPPKDIHISPSGDHFLLEWSVSLGDSQVSWLSSKDIEFEVAYKRLQDSWEDASSLHTSNFQVNLEPKLFLPNSIYAARVRTRLSAGSSLSGRPSRWSPEVHWDSQPGDKAQPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPAAPEEKCSPVVKEPQASVYTRYRCSLPVPEPSAHSQYTVSVKHLEQGKFIMSYYHIQMEPPILNQTKNRDSYSLHWETQKIPKYIDHTFQVQYKKKSESWKDSKTENLGRVNSMDLPQLEPDTSYCARVRVKPISDYDGIWSEWSNEYTWTTDWVMPTLWIVLILVFLIFTLLLALHFGRVYGYRTYRKWKEKIPNPSKSLLFQDGGKGLWPPGSMAAFATKNPALQGPQSRLLAEQQGVSYEHLEDNNVSPLTIEDPNIIRDPPSRPDTTPAASSESTEQLPNVQVEGPIPSSRPRKQLPSFDFNGPYLGPPQSHSLPDLPGQLGSPQVGGSLKPALPGSLEYMCLPPGGQVQLVPLSQVMGQGQAMDVQCGSSLETTGSPSVEPKENPPVELSVEKQEARDNPMTLPISSGGPEGSMMASDYVTPGDPVLTLPTGPLSTSLGPSLGLPSAQSPSLCLKLPRVPSGSPALGPPGFEDYVELPPSVSQAATSPPGHPAPPVASSPTVIPGEPREEVGPASPHPEGLLVLQQVGDYCFLPGLGPGSLSPHSKPPSPSLCSETEDLDQDLSVKKFPYQPLPQAPAIQFFKSLKY
What is the function of this protein?
In mouse, there are two classes of high-affinity IL3 receptors.  One contains this IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors.
What are the official names of this protein?
Interleukin-3 receptor class 2 subunit beta, IL-3 receptor class 2 subunit beta, IL-3R class 2 subunit beta, Colony-stimulating factor 2 receptor subunit beta-2, Interleukin-3 receptor class II beta chain.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TLX2_MOUSE
Sequence: MEPAVLAAHHLPHHEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGFHGASGYAPAGSLASLPRGSGVGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
What is the function of this protein?
Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'.  Binds DNA via its homeobox.  Required for normal cell death of enteric neurons in the gastrointestinal tract.  Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract.
What are the official names of this protein?
T-cell leukemia homeobox protein 2, Enteric neuron homeobox protein, Homeobox TLX-2, Homeobox protein Hox-11L1, Hox11L.1, PMUR10F.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBD_BPSYS
Sequence: MTTSTLQAPTRGWFDVLDDWLKRDRFVFVGWSGLLLFPTAYLAIGGWLTGTTFVTSWYTHGLASSYLEGANFLTAAVSTPADAMGHSLLLLWGPESQGDFIRWCQLGGLWAFVALHGAFALIGFMLRQFEISRLVGIRPYNAIAFSGPIAVFVSVFLIYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLSAIHGVTVENTLYEDGEQANTFKAFDTTQEEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVMGLWTSSIGIIGLALNLRAYDFVSQEVRAAEDPEFETFYTKNILLNEGLRAWMAPVDQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Host cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SEPT8_XENTR
Sequence: MAATDVERVSNEEKRSLAMTGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFETEEASHYENGVRLRPRTYDLQESNVHLKLTIVDTVGFGDQINKDDSYRSVVDYIDTQFENYLQEELKIRRSLFNYHDSRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDDAVAEINSVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDNDPDTQPFSLQETYEAKRKEFLGELQRKEEEMRQMFVNKVKETEAELKDKERELQEKFMQLKRVHQEESKKVEDKRRDLEEEMNSFNRRKAAMEALQSQSFQATSQQPLKKDKDRKN
What are the official names of this protein?
Septin-8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Presynapse. Note=Expressed in axons of immature neurons, localizes to synapses in mature neurons.
Protein: MURD_BURVG
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRIADTREAPPNLAALQAEGIDAEFVGGPFTPALLDGGIDIVGLSPGLSPLEPALAALLAAASERAIAVWGELEFFAQALRALGTSGYQPKVLAITGTNGKTTTTSLTGLLCQRAGKKVAVAGNISPAMLDRLASAIDETALPDVWVLELSSFQLETARTFAPDAAAILNITQDHLDWHGSFDAYAAAKGRIFGATTTRVLNRDDAAVMKFAPAAGAADAARTVTFGLGEPTRDGDYGLSRDNGIAWLVEAIDRDAPDETTTTRRRKRDGAHTPDIAHKRLMPVDALRIRGLHNAANALAAFALARAIDLPAAPLLHALREYRGEAHRVEVIATIDDVDYVDDSKGTNVGATVAALDGLAQKIVLIAGGDGKGQDFAPLVAPVARWCRAVMLIGRDAPALRATLADTGVPLADHATLEGAVRAAAELAEPGDAVLLSPACASLDMFRNYAHRADVFRAAVDEIAIDKGATP
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGA14_ORYSJ
Sequence: MAKAMCSLGACLAVMLVVLAAAVAGVGCSIVSYDGRSLILDGERRIVISGSIHYPRSTPEMWPDLIKKAKEGGLNAIETYVFWNGHEPRRREFNFEGNYDVVRFFKEIQNAGMYAILRIGPYICGEWNYGGLPVWLRDIPGIKFRLHNKPFENGMEAFTTLIVKKMKDANMFAGQGGPIILAQIENEYGYTMLQPENIQSAHEYIHWCADMANKQNVGVPWIMCQQDNDVPPNVVNTCNGFYCHEWFSNRTSIPKMWTENWTGWYRDWDQPEFRRPTEDIAFAVAMFFQMRGSLQNYYMYHGGTNFGRTAGGPYITTSYDYDAPLDEYGNLRQPKYGHLKELHSVLMSMEKILLHGDYIDTNYGDNVTVTKYTLNATSACFINNRFDDRDVNVTLDGTTHFLPAWSVSILPNCKTVAFNSAKIKTQTTVMVNKTSMVEQQTEHFKWSWMPENLRPFMTDEKGNFRKNELLEQIVTTTDQSDYLWYRTSLEHKGEGSYVLYVNTTGHELYAFVNGKLVGQQYSPNENFTFQLKSPNYGGSFELLPAGIVGGPVKLIDSSGSAIDLSNNSWSYKAGLAGEYRKIYLDKPGNKWRSHNSTIPINRPFTWYKTTFQAPAGEDSVVVDLHGLNKGVAWVNGNSLGRYWPSYVAADMPGCHHCDYRGVFKAEVEAQKCLTGCGEPSQQLYHVPRSFLNKGEPNTLILFEEAGGDPSEVAVRTVVEGSVCASAEVGDTVTLSCGAHGRTISSVDVASFGVARGRCGSYDGGCESKVAYDAFAAACVGKESCTVLVTDAFANAGCVSGVLTVQATC
What are the official names of this protein?
Beta-galactosidase 14, Lactase 14.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RAMAC_XENTR
Sequence: MAEALGAQELYEKMFEQRFTANDKEYQEYLKREQDQPPIVEDWKMGNQRNTDRYRDNRHHRGWDGRQNWSSNSYNQSYGRGGWGNSYNQYRQDRHNYQQGHYTHNPSNQRFHSDRY
What is the function of this protein?
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.  Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT.  Regulates RNMT expression by a post-transcriptional stabilizing mechanism.  Binds RNA.
What are the official names of this protein?
RNA guanine-N7 methyltransferase activating subunit, Protein FAM103A1, RNA guanine-7 methyltransferase activating subunit, RNMT-activating mRNA cap methyltransferase subunit, RNMT-activating mini protein, RAM.
What is the protein family that this protein belongs to?
Belongs to the RAM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF3_SYNFM
Sequence: MNHRHRQEIDRRRTFGIISHPDAGKTTLTEKLLLFGGAIQLAGAVKARKASRHATSDWMAIERERGISVTTSVMKFNYRDFEINLLDTPGHQDFSEDTYRVLTAVDSALMVIDSAKGVEPQTEKLMEVCRMRNTPIITFINKLDREGQSPLALLGEIEDKLQIECTPLSWPIGSGKSFKGVYDLLGKKLHLFAPGQETRTNGGMVFDDLSDAALDELLGRQAVQLREDVELLEGAANPLEQEHYLRGNQTPVFFGSALNNFGVRELLDAFVQMAPPPHARPTVSREVSPYEDQFSGFVFKIQANMDPAHRDRIAFLRICSGKYTRGMKVIHHRAGREMNIANATIFLAQDRTNIDEAYPGDIIGIHNHGTIKIGDTFTEKEPLRFTGIPSFAPEHFRRVILKNPLKVKQLRKGLAQLTEEGAVQVFRPLAARDYILGAVGVLQFDVTVARLRTEYGVDADYEPAGYAAARWVESDSRNVMEEFEKENRGSLALDGEDRLTYLAPNEWRLGFVMEDWPRIRFRKSMECN
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSK_PSEPK
Sequence: MKKSTATPAPLPVPLWRQQLHYRLKEGALIAVGALCLYLWMALLTYDTSDPGFSHTSNVDQVQNAAGRAGAYFADILFMVLGYFAYIFPLLLAVKTWQIFRERHQPWDWSGWLFSWRLIGLVFLVLSGAALAHIHFHPPASLPFSAGGALGESLGDLARNLLNVQGSTLMFIALFLFGLTVFTDLSWFKVMDLTGKITLDLFELVQGAATRWWEARNERKRLEAQLREDEPVFKAAPMAAEKREPAKPSLRERILKREEPPAQPVEPREPTLAREPIVPPRETAPEALAPRETVVPRQQHAAPTIVPPSAASRAPEPSKRAMKEKQAPLFVDSAVEGTLPSISILDPAEQKKIEYSPESLAGVGQLLEIKLKEFGVEVAVDSIHPGPVITRYEIQPAAGVKVSRIANLAKDLARSLAVTSVRVVEVIPGKTTVGIEIPNENRQMVRFSEVLATPQYDEQKSPVTLALGHDIGGKPVITDLAKMPHLLVAGTTGSGKSVGVNAMILSILFKSSPEDARLIMIDPKMLELSIYEGIPHLLCPVVTDMKDAANALRWSVAEMERRYKLMAAMGVRNLAGFNRKIKDAQEAGEVIHDPLYRRESMDDEPPALKTLPTIVVVVDEFADMMMIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSKIDSRTIIDQGGAEQLLGHGDMLYMPPGTSLPIRVHGAFVSDDEVHRTVEAWKLRGAPDYNDDILNGVEEAGSGFDGGGGGGEGDDAETDALYDEAVQFVLESRRASISAVQRKLKIGYNRAARMIESMEMAGVVTPMNSNGSREVIAPGGPRD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: PYRB_BRUA4
Sequence: MTNQTVPPLFPHRHLLGIKGLSPLDILCLLDLADQEIAVSRQPEKKKSVLRGRTQINLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMQPDILVIRHASAGAAALLAQKVGCSVVNAGDGAHEHPTQALLDALTIRRAKGGIENLIVAICGDVLHSRVARSNILLLNALGARVRVVAPSTLLPSGMADMSVEVFNSMEEGLKDADVVMMLRLQRERMAGSFVPSVREYFRFYGLDKEKLKVAKPDALVMHPGPMNRGVEIASDVADGPQSVIQQQVEMGVAVRMAVMEALLDPRRNPSNGEAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UVRC_CERS4
Sequence: MQDNETDGRDVPTGHAVIQGYLKTLDGSPGVYRMLDAQSQVLYVGKARNLRARVSNYARPSGHSGRIARMIRETASMMFLTTRTETEALLLEQNLIKQLKPRYNVLLRDDKSFPNILIAKDHPFPMLKKHRGKKSEKGSYFGPFASAGAVNRTLNQLQRVFLLRTCSDATFESRTRPCLLFQIKRCSAPCVGRVPAEDYAELIGDAERFLQGRTTKVQANLAEQMQAASEAMEFERAAALRDRIKALTQVQSSQGINPRGVAEADVIAVHLEGGQACVQVFFIRANQSWGNRDFFPRTGAGAEEPEILEAFLAQFYDDKEPPRMILLSHPVDNPDLVGQLLSERAGRKVTLGVPQRGEKAELVENAARNARESLARRMAESATQNRLLAGLAEAFELDAAPKRIEVYDNSHIQGTNAVGGMIVAGPEGFLKSQYRKFNIRGAAGAQGDDFGMMKEVLTRRFERLLKEDPERKTDAWPDLLLIDGGAGQVSAVQEILQELGVDDVPFIGVAKGIDRDAGKEEFHRPGEPPFALRMNDPVLYFVQRLRDEAHRWAIGAHRAKRAKAVSATPLDEIPGVGAARKRALLAHFGSAKAVARAGVPDLCAVEGISETMAQSIHDYFHGS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_CAMLR
Sequence: MKFNPFLEAIKTYESGKDMDLVAKEYGLKEVIKLASNENPYGTSKKAKEAIINNAHLAHLYPDDTMSELKQALAQKYDILKENLIIGSGSDQIIEYIVHAKLDHSKAYLQCGVSFAMYEIYAKQLGVKVYKTPSLTHDLNELYELYQKHKNEIKVIFLCLPNNPLGECLDASAVFEFLEKIDEDCLVAIDGAYNEFASFKDSKKHINPKELIHKFQNAVYLGTFSKLYGLGGMRVGYGIACKEIINAFYKLRAPFNVTNLSLKAAVAALDDDEFVQKTLENNFSQMKLYEDFAKNYKIRYIPSYTNFITYFFDEKNSTDLSEKLLKNGIIIRNLQSYGLNAVRISIGTEYENSRFFEEFSKNF
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: THG1_NEUCR
Sequence: MANSKFEYVKQFEQPDSLLPNTWIVVRLDGRGFTKFSTKYAFEKPNDKRALDLMNAAARSVMSELPDITIAYGVSDEYSFVFHKSCTLFERRASKLVSTIVSTFTAYYIHHWPTYFVDGPPLSPPLPSFDGRAVCYPSVQNLRDYMSWRQVDCHINNLYNTTFWALINQGGMDGTAAELMLKGTFSADKNEILFKKFGINYNNEPEMFKKGSVVFRNYELVEPGTKKVSEEEAEEMSSSAVPEVKSKSQVEKDKKVRTKAKIVVEHLDIIRDEFWERRPWLLSGTPGKVPKEP
What is the function of this protein?
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
What are the official names of this protein?
tRNA(His) guanylyltransferase, tRNA-histidine guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(His) guanylyltransferase family.
Protein: DNAA_SHEPC
Sequence: MAVSLWQQCIGRLQDELPAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVREKYINIINQFFTEQMGSDAPKLRFDIGSRPSAKKFEPAPVATVRAPNTQTKATVGTYFNTQAEPIANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCC_ECOLI
Sequence: MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIISMDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSLKEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGLHTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRADVARTTLNESELAALYACVEAAKCSNQSPLHIRWQYQEETRECEFYENELEDLWLPLLNRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIVALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRVETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGLLEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEELWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP
What is the function of this protein?
Probable chaperone.  Has ATPase activity.  Not stimulated by DnaJ.
What are the official names of this protein?
Chaperone protein HscC, Hsc62.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YEAH_ECOBW
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKG
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: DPHB_METVS
Sequence: MLVMAGLGLYDELDVTLKTVEFAKKVDKIYAEFYTAILTGTTIEKIEKTLQKEITVLNREKVEYETNKLIEEAKEKDIMFLTAGDPMVATTHVDIAVEARKKGIEVIILNAPSIYSAIGITGLQLYKFGKTTSIVFPEPNYFPETPYDVIKDNLSLGYHTLCLLDIQTDKQKFMTANEGLSVLLEIEEKRKEKIIDENTKVLVVARAGSIKPGLFYGKIKDLIKHDFGTPLHCVIILGKLHFMETDALKYLFENI
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: BBP_ASHGO
Sequence: MTRLVWFCMQVAYCLHGWDWDIMDRGRSSNSYDSLWGGKARDNPIVSQLPLQYRIRSALTQEQQTAYQVMYRIQEITIKLRTNDLNPPTSRYRSLSPPPVYDSQGKRTNTREHRYRKKLEEERHRLVEIALKMIPHFIAPDDYRRPSKFQDKYYIPINDYPEINFVGLLLGPRGNTLKQLQQQSGCKIVIRGRGSVKEGKAATDLPKGAMNMNEPLHCVISADTEEKIPLGINAVESIIIKAITSPEGQNDLKRGQLRELAVLNGTLREDNRPCPLCGEQGHKKWECSSNPSLSMTVICQRCNQPGHAARDCTSPLNEFGKRTSDGPEFRETKKLQQDAPPPSGPVGSHPSAPGSGSANSGVAPASLHPPGTMAPPGALPPPGSLAAPGTLPPPAALPAPAAPGTLPPPVALPAPATLPQAGVPPAPDASPAVKTAVPIEGPPAPPQTAPPLRQTAATASSAGSSQSAQEEPENARNGVEKAAPGPPAAVLPPPPPPPPPPPPPPSS
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
What are the official names of this protein?
Branchpoint-bridging protein.
What is the protein family that this protein belongs to?
Belongs to the BBP/SF1 family.
What are the subcellular locations of this protein?
Nucleus.