PharMolix/UniProtQA huggingface dataset:
Protein: UVRA_ZYMMO
Sequence: MLSTISIRGAREHNLKNVSIDIPRNKLVVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLEMMQKPDVDHIEGLSPAISIEQKTTSKNPRSTVATVTEIYDYMRLLWARVGIPYSPATGLPITAQTVSQMVDRVMALPEGSRLHLLAPVVRGRKGEYRKEMAEWQKAGFSRLRIDGEYYLIEEAPKIDKKRKHDIEVVVDRLVIKEGLETRLAQSLETALKLAGGIAISEPADEGSFEPMLFSEHFSCPVSGFTIPEIEPRLFSFNAPQGACPACDGLGEKPYFDVRLIVPNESLSLAKGALMPWARSTPPSPYYMQILSSLARYYDFSLETPWKKLPEKIQNVILYGSEGEVIPLRFSEGNQIYEVEKAFEGVIRNLERRLVTTDSESIREDIGRYQSAAPCEVCHGARLRPEALAVLIDHHNISDVTKMTVKPALEFFRQLPEKLTEAQNQIAERILKEIIERLGFLDNVGLDYLSLDRSSGTLSGGESQRIRLASQIGSGLSGVLYVLDEPSIGLHQRDNDRLLETLKRLRDLGNSVLVVEHDEDAIRLADYVVDMGPGAGVMGGKVIAAGSPQDIIDCPDSLTGAYLSGRREIAVPDKRRKGNGKKLTIKGATANNLQNVTASIPLGTFTCVTGVSGSGKSSLILDTLYTAAARELNGARLISGDYKSISGLEHLDKVIDIDQSPIGRTPRSNPATYTGAFTAIREWFAKLPEAQARGYKAGRFSFNVKGGRCEACQGDGVKKIEMHFLPDVYVTCDVCHGARYNRETQEVKFKGQSIADVLNMTVDQAAEFFEAVPSIRDKMAMLARVGLGYIKVGQQATTLSGGEAQRVKLAKELSKRATGRTLYILDEPTTGLHFEDVRKLLEVLNALVDQGNSIVVIEHNLDVIKTADWLIDLGPEGGTGGGQIIAAGTPEKVAETEGSYTGHYLKRMLQPK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSSE1_PSEAE
Sequence: MAELTLQERLQPSLLDRLTDDEPGNLKEAAERRVLTLNQLKASVLRDLAWLFNTTSLFDHGPAARMPAGNSVLNYGLPALAGHTASSVDVHAIEALLTETIATFEPRIIRSSLRVRAQLLPGEMDHNALSFEIEGDLWAEPAPLRLLLTTNLDLETGHVRVAQGERRRT
What is the function of this protein?
Core component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species.  Plays a role in correct elongation and stability of TssB1-sheath (PubMed:21873404, PubMed:22906320).  Functions downstream of TssK1 and prevents detachment of TssB1-sheath and its premature disassembly.  Once bound onto the sheath via an interaction with TssB1, provides an ideal docking point for ClpV1 to be recruited to the sheath (PubMed:31379775).
What are the official names of this protein?
Type VI secretion system component TssE1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GM_EBVB9
Sequence: MKSSKNDTFVYRTWVKTLVVYFVMFVMSAVVPITAMFPNLGYPCYFNALVDYGALNLTNYNLAHHLTPTLYLEPPEMFVYITLVFIADCVAFIYYACGEVALIKARKKVSGLTDLSAWVSAVGSPTVLFLAILKLWSIQVFIQVLSYKHVFLSAFVYFLHFLASVLHACACVTRFSPVWVVKAQDNSIPQDTFLWWVVFYLKPVVTNLYLGCLALETLVFSLSVFLALGNSFYFMVGDMVLGAVNLFLILPIFWYILTEVWLASFLRHNFGFYCGMFIASIILILPLVRYEAVFVSAKLHTTVAINVAIIPILCSVAMLIRICRIFKSMRQGTDYVPVSETVELELESEPRPRPSRTPSPGRNRRRSSTSSSSSRSTRRQRPVSTQALVSSVLPMTTDSEEEIFP
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: RUVB_BACP2
Sequence: MDERLVSTEADNHESAIEQSLRPQTLSQYIGQQKVKDNLSVFIEAARMRQETLDHVLLYGPPGLGKTTLASIIANEMNVQLRTTSGPAIERPGDLAAILTSLEPGDVLFIDEIHRLQRSIEEVLYPAMEDFCLDIVIGKGDTARSVRLDLPPFTLVGATTRVGLLTAPLRDRFGVHARLEYYEQRDLAHIVSRTAELFEIGIDLRSAEEIARRSRGTPRVANRLLRRVRDFAQVLGNHSITEDIAEDALERLQVDKLGLDHIDHKLLLSMIEKFRGGPVGLDTISATIGEESHTIEDVYEPYLLQIGFLQRTPRGRVVTREAYEHFQMEVPIRD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LPXB_THIDA
Sequence: MVAGEASGDLLGAHFFDALKKNRPGLTAAGIAGPRMVEAGVKAIYPSEKLAVNGYVEVLRHLPELLWIRARITRHFLRERPRVFVGIDAPDFNFTLEAALKRAGVPTIHFVSPSIWAWRPERIERIKQAVSHMLVVFPFEEAIYRDAGIPVSYVGHPLADVIPLQAPTGAARATLGLGDGPIVALLPGSRLSEVDRHARLMLEAAMQVRAKEMDVRFVLPAASEAARERIARAAQGLDLPLTVLAGRSHQALAACDVAVVASGTATLEAALFKKPMVITYRVPALTARLMRKKALLPWIGLPNILARDFVVPERVQEAATPDALAADVLAWLGDAARRAALAVTFDALHRDLRQGASARIAAAIAPYLEAAR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: MTBB3_METBA
Sequence: KLAEILMMPGKTVSVEQGMEIPVTHDIGTIRLDGDQGNSGVGIPSSRLVGCMTHERAFGADTMELGHIDYSFKPVKPVVSNECQAMEVCQQNMVIPLFYGAMPNMGLYYTPDGPFENPGDLMKLFKIDKAKESMEHAAEHLTRDTVWVMQKLFASGADGVNFDTTGAAGDGDMYGTLYAIQALRKEFSDMYIEAGMAGEMVLGMHGELEYNGVRLAGLWPHEQAPLVAKAGANVFGPVCNTNTSKTSAWNLARAVTFIKAAVGASPIPCHVNMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGIOIGVGDPMGMPISHIMASGMTGIRAAGDLVARMEFSKNMRIGEAKEYVAKKLGVDKMDLVDEHVMRELREELDIGIITSVPGAAKGIAAKMNIEKLLGIKINSCNLFRKQIA
What is the function of this protein?
Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC (By similarity).  No evidence for expression of this protein has been found after growth under presumably inducing conditions (PubMed:16096277).
What are the official names of this protein?
Dimethylamine methyltransferase MtbB3, DMA methyltransferase 3, DMAMT 3, Dimethylamine--corrinoid protein methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the dimethylamine methyltransferase family.
Protein: KHSE_SYNS9
Sequence: MAQPRIGQRVIVDVPATTANLGPGFDCLGAALDLNNRFAMRRIEGGGERFELIIEGSEGSHLRGGPENLVYRAAQRVWKAAGLEPVALEARVRLAVPPARGLGSSATAIVAGLMGANALVGEPLSKEKLLELAIDIEGHPDNVVPSLLGGLCMTAKAASQRWRVVRCEWTSTVKAVVAIPSIRLSTSEARRAMPKAIPVSDAVVNLGALTLLLQGLRTGNGDLISDGMHDRLHEPYRWRLIKGGDQVKQAAMDAGAWGCAISGAGPSVLALCAEDKGMAVSRAMVRAWEAAGVASRAPVLNVQTTGSHWQPADDE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_BRUAB
Sequence: MAKVIGIDLGTTNSCVAVMDGKNAKVIENAEGARTTPSIIAFTDGDERLAGQPAKRQAVTNPEGTLFAVKRLIGRRYDDPMVTKDKDLVPYKIVKGDNGDAWVEVHGKKYSPSQISAMILQKMKETAESYLGETVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKSEGKTIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDIRLVEYLVAEFKKESGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADQTGPKHLAIKLSRAKFESLVDDLVQRTVEPCKAALKDAGLKAGEIDEVVLVGGMTRMPKIQEVVKAFFGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDADIEKMVKDAEANAEADKKRRESVEAKNQAESLVHSTEKSLAEYGDKVSADDKKAIEDAIAALKTSLEGEDAEDIKAKTQALAEVSMKLGQAMYEAAQAAEGAGAEGGEQASSSKDDVVDADYEEIDDNKKSS
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y1774_YERPE
Sequence: MLAGMPSLSHEEQQEAVERIHKFMSEGMSSGEAIALVAAEIRERHQNDPQAMAIFEDHDFDEHTESDYRRDDEPDADDIEDPYEG
What are the official names of this protein?
UPF0181 protein YPO1774/y2534/YP_1619.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: ENO_STRPN
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.  Binds plasminogen when expressed at the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to the degradation of the extracellular matrix and transmigration of the bacteria.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface, probably in complex with plasminogen.
Protein: CCKN_MACGI
Sequence: DYMGWMDF
What is the function of this protein?
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut.  Its function in the brain is not clear.  Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
What are the official names of this protein?
Cholecystokinin, CCK.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_BIFLO
Sequence: MFSPRKIPMNVRGISMANGPVLVVDFGAQYAQLIARRVREAGVYSELVPHSMPVDEILAKDPKAIILSGGPASVFEPGAPTIDTKVFESGVPVLGICYGFQVMAYELGGKVDKAALGEYGKTSATIDDAAGILADSPAEQTTWMSHGVAVEQAPAGFEVLAHTEGAPVAAMADESRKLYGVQWHPEVKHSPLGQKLIENFLHRCAALPNDWDASSIIEDQVKKIREQVGDAEVICGLSGGVDSAVAAALVHKAIGDQLTCVFVDHGLLRKGEVEQVKHDFVAATGIRLITVDAADDFLDALAGVSEPERKRKIIGEKFIRTFEKAQRQVLEEAGARGKEVKFLVQGTLYPDVVESGGGDGAANIKSHHNVGGLPKDIKFQLIEPLRTLFKDEVRAIGTELGLPDEIVWRQPFPGPGLGIRIIGEITKERLDLLREADAIAREELSKAGLDRDIWQCPVVLLADVHSVGVQGDERTYGSPIVLRPVSSEDAMTADWSRVPYDVLATISTRITNECRQINRVVLDCTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y1478_STAHJ
Sequence: MNPYEQYMQELAQQMRAELTENGFESLETSEDVSNYMKNVNEEDTTFVVINSTCGCAAGLARPAAVAVAEQNDKKPTNKITVFAGQDKEATQTMREYIQQVPSSPSYALFKGTELKHFIPREHIEGRDIQDICMDIKDAFDENC
What are the official names of this protein?
UPF0403 protein SH1478.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: KGUA_XANOR
Sequence: MRGTLYIVAAPSGAGKSSIVNATLARDPKIALSISFTSRAPRPGERHSEHYHFVSAEEFQGMIAAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSRQALDERMRKRGQDSEDVMAQRLAAAREEMLHFEEFDYVIINETFDTAVSEMCAIFTASRLRRQAQQQRHAGLIQALLD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTOR1_MOUSE
Sequence: MGCCYSSENEDSDQDREERKLLLDPSSTPTKALNGAEPNYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.  LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes.  Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes.  May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes.  May also play a role in RHOA activation.  Involved in the control of embryonic stem cells differentiation; together with FLCN it is necessary to recruit and activate RRAGC/RagC and RRAGD/RagD at the lysosomes, and to induce exit of embryonic stem cells from pluripotency via non-canonical, mTOR-independent TFE3 inactivation (PubMed:30595499).
What are the official names of this protein?
Ragulator complex protein LAMTOR1, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1, Lipid raft adaptor protein p18.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR1 family.
What are the subcellular locations of this protein?
Late endosome membrane; Lipid- anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Lipid- anchor.
Protein: LON_CHLT3
Sequence: MTDHTKEHENTPSMGFLDGLVNSISQQPKAIEEEIKFDGALPVLPLRNTVLFPDVIVPIGVARQRSIALLESLAPNSPVVFLMQTDADIDAPTPDELHKNGSVGLVLRTLRMPDNSMSVIVQGVKRVVVEAFTQTEPYLAAKVTPKDEEELEGVEFDAYARTTKQLASKIIELSPNSPNEASYAIQSIENTRFLIHFIASNISVPAAEKQKMIEAEGMKARAERLIHFLNREVQVLELSKQIQTKVKTDMDRSQREFILRQQLKTIQQELGEQDAQMQDVEKLREAVEKKNLPEEVTSVVSKEIDKLSRIPQASPDYSVTRNYVDTILALPWGHFSETVINLHEAEKILNQDHYGLGKVKDRILEYLAVLKLKSNMKAPILCFCGPPGVGKTSLGRSIARALGRKFIRISLGGVRDEAEIRGHRRTYIGSMPGRIIQGIKTAGTSNPVFMLDEIDKIGADFRGNPSSALLEVLDPAQNNAFSDHYLEIPYDLSKVMFIATANTLDPIPVPLRDRMEIINLSGYTEYEKLHIAERYLIPRQLEEHGIRPEDVSFDALTTKKIINAYTREAGVRNLERQIANVCRVIAKDIVIRRESDQPDETPITVVTADLKKYLGMEQFYPDVSEPVMLSGVAVGLAWTPVGGDILFIESTVMKGTGRLILTGQLGDVMKESAQAALSYLKSCADYFKIPDEAFRYWDVHVHVPQGAIPKDGPSAGVTILTSLASIYTQRKVKPCIAMTGEITLRGRILPVGGIKEKVLAAKRAGITEILLPEKNEKDVKEALETNGGAFSDVSFKYFHEMDDLIDYVLEPAENGAPQFKVEDKDHTPETTGNESE
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_VIBCM
Sequence: MAKEFLIELGTEELPPKQLRTLAEAFAANFAAELATADIAHEGVTWFATPRRLALKVANLAESQPDRVVEKRGPAVNVAFDADGKPTKAAEGWARGNGITVEQAERLVTDKGEWLLFKEQVQGQQTASVVVEMAAKALANLPIAKPMRWGDKETQFIRPVKTLTILFGSELIQGEILGVASARTLRGHRFMGEAEFTIESAEQYPAILEERGKVIADYATRKAMIIEGSQQAAQQLGGIADLEDALVEEVTSLVEWPVVMTAKFEEKFLKVPAEALVYTMKGDQKYFPVYDASKKLLPNFIFVSNIESKEPRHIVEGNEKVVRPRLADAEFFFNTDRKRPLVDRLPLLENAIFQQQLGTIKDKTDRITELAGYIAEQIGADVEKSKRAGLLAKCDLMTSMVFEFTDTQGVMGMHYARHDGEAEEVAVALNEQYMPRFAGDELPSRGVSAAVAMADKLDTIVGIFGIGQAPKGSDPFALRRASLGVLRILVEYGYQLDLVDLIAKAKSLFGDRLTNANVEQEVIEFMLGRFPTWYQDAGFSIDIIQAVLARNPTKPADFDQRVKAVSHFRALEEAEALAAANKRVGNILAKYDGELGEEIDLALLQEDAEKALAEAVEIMAEALEPAFATGNYQEALSKLAGLRAPVDAFFDNVMVMADDEALKKNRLTLLNKLRNLFLQIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNAA_ECODH
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: MNN1_YEAST
Sequence: MLALRRFILNQRSLRSCTIPILVGALIIILVLFQLVTHRNDALIRSSNVNSTNKKTLKDADPKVLIEAFGSPEVDPVDTIPVSPLELVPFYDQSIDTKRSSSWLINKKGYYKHFNELSLTDRCKFYFRTLYTLDDEWTNSVKKLEYSINDNEGVDEGKDANGNPMDEKSERLYRRKYDMFQAFERIRAYDRCFMQANPVNIQEIFPKSDKMSKERVQSKLIKTLNATFPNYDPDNFKKYDQFEFEHKMFPFINNFTTETFHEMVPKITSPFGKVLEQGFLPKFDHKTGKVQEYFKYEYDPSKTFWANWRDMSAKVAGRGIVLSLGSNQFPLAVKFIASLRFEGNTLPIQVVYRGDELSQELVDKLIYAARSPDFKPVENNYDNSTNVPQEIWFLDVSNTIHPKWRGDFGSYKSKWLVVLLNLLQEFVFLDIDAISYEKIDNYFKTTEYQKTGTVFYRERALRENVNERCIARYETLLPRNLESKNFQNSLLIDPDHALNECDNTLTTEEYIFKAFFHHRRQHQLEAGLFAVDKSKHTIPLVLAAMIHLAKNTAHCTHGDKENFWLGFLAAGHTYALQGVYSGAIGDYVKKTDLNGKRQEAAVEICSGQIAHMSTDKKTLLWVNGGGTFCKHDNAAKDDWKKDGDFKKFKDQFKTFEEMEKYYYITPISSKYVILPDPKSDDWHRASAGACGGYIWCATHKTLLKPYSYNHRTTHGELITLDEEQRLHIDAVNTVWSHANKDNTRSFTEEEIKELENSRHEQS
What is the function of this protein?
Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose.  Implicated in late Golgi modifications.
What are the official names of this protein?
Alpha-1,3-mannosyltransferase MNN1.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: O164_CONST
Sequence: MKLTCMVIVAVLLLTACQLITADDSRGTQKHRSLRSTTKVSKATDCIEAGNYCGPTVMKICCGFCSPYSKICMNYPKN
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like SO-4, Omega-conotoxin SO4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_BIFA0
Sequence: MAKARVYELAKELGVDSKTVLEKLKDMGEFVKSASSTVEAPVVRRLKAAFPKDGGNDSRPSAKKSSTPKSGAPAAAKPAATPAAVAGATPATAAPSAPKPGQRSNTSAKPGAHNTRRNEQTPRPGQNGGQRGATARPHAPGKPGANAGGTRNGGKAAPTPHAPQHGGNRGGSNNAPKPGANAAQHAPRPGNNPFSRKQGMHTPTPGDIPRPHPMARPTVNNNERRGGGNGRPGQRGGFRPRPGQGGSGAPKPGSWGQHRQGAGSGGGRPGGNRFGGGNGGNNFQNNGPSNGPSRGGGRGRGGAAGAFGRQGGKSSKARKNRLAKRHEYEELKAPVIGGVRIPTGNGQTIRLRQGASLADLAEKINVNPAALVTVLFHLGEMATATQSLDESTFQILGEEIGWNIKIVSAEEEDKELLQQFDIDLESEELQEEADLKPRPPVVTVMGHVDHGKTRLLDTIRRTNVVAREAGGITQRIGAYQVTVDLEGEERKITFLDTPGHEAFTAMRARGAELTDIAILVVAADDGVMPQTVEAINHAQSAHVPIVVAVNKIDVPGANPEKVRGQLTEFGLVPEEYGGSTMFVDISAKQGTNVDKLLEAVLLTADAELDLRANPDMDARGATVEARLDKGRGAVATVLVQSGTLHIGDSIVAGTSYGRVRAMLDENGKHMKEALPSTPVQVLGLTSVPTAGDLFLVAPDDRAARQIAEKRQATERAAQLAKRRKVVSLEEFKKKFAESEIDMLNIVIKGDSSGSVEALEGSLMKIEVSDEVGIQVIHRGVGAITQNDVNLASVDKAVIIGFNVRPNRQVADLAEREGVEIKYYSVIYKAIEDIEASLKGMLKPEYEEVTTSHSEIREIFRSSKFGNIAGVMVLDGEVKRGTKARILRDGVTTFNDLEISSLRRFKDDVKSVTEGYEAGINLGNFNDIEIGDVIETFEMREIERK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_METKA
Sequence: MTVLSDRDIKRALEEGDIVVKPLEEEYLEEALGPASLDLRLGNEFVVFKTLHKPCIDPTVDAGENTERIVIDEDEEFVINPGELVLAVTHEWIEINAPDITGVLHGRSSLGRLGIQAHVEAGYVDPGWRGRLTLELVNFNPMPVKLRPGMRVVQIVFHRLSSPAERTYAESSGKYHGDERPSPSKMHLDFCRG
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TXLA_SYNY3
Sequence: MTPAKIRNALLAVVAIALSAAVYLGFQTQTQGISLEAQAQRAIPLATALDNGRPTLVEFYADWCTSCQAMAPDLAELKKNYGGSVNFAMLNVDNNKWLPEVLRYRVDGIPHFVYLDDTGTAIAESIGEQPLRVLEQNITALVAHEPIPYANVTGQTSVVENRTIEADPTSPRSHGNPRPS
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein TxlA homolog.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DAPAT_PROM1
Sequence: MVKVNADYLKLKAGYLFPEISRRITEFSSKNPNANLIRLGIGDVTEPLPLACREAMKAAIEEMGTEDGFRGYGPEQGYKWLREIISENDYISRGCEISAEEIFVSDGSKCDSSNILDILGKENKIAVTDPVYPVYVDTNVMTGRTGEANSVGEYTGLSYIPINSENGFEASIPKDKFDLIYLCFPNNPTGAVATKEQLVSWVKYAKENNSLILFDAAYEAFIKDESIPHSIFEIEGARDCAIEFRSFSKNAGFTGTRCAFTVIPKSLKGKAGIETVDLWSLWNRRQSTKFNGVSYVVQRGAEAVYSKEGKIQIKKLVSFYMDNAEIIKSNLTAAGFEVFGAVNAPYAWIKTPKNMSSWDFFDFLLEKANVVGTPGSGFGAAGEGYFRLSAFNSRENVEKAMERIVKLK
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.