PharMolix/UniProtQA huggingface dataset:
Protein: PELP1_RAT
Sequence: MAAAVLSGPTTGSPAGAPGGPGGLSAAGSGPRLRLLLLESVSGLLQPRTGSHVAPVHPPIQWAPYLPGLMCLLRLHGTAGGAQNLSALGALVNLSNAHLSSIKTRFEGLCLLSLLVGESPTELFQQHCVSWLRSIQQVLQSQDSPPTMELAVAILRDLLRYASQLPTLFRDISTNHLPGLLTSLLGLRPQCEQSALEGMKACVTYFPRACGFLKGKLASFFLSRLDSLNPQLQQLACECYSRLPSLGAGFSQGLKHTENWEQELHSLLTSLHSLLGSLFEETETAPVQSEGPGVEMLLSPSEDDNTHVLLQLWQRFSGLARCLGLMLSSEFGAPVSVPVQEILDLICRILGISSKNINLLGDGPLRLLLLPSLHLEALDLLSALILACGGRLLRFGALISRLLPQVLNTWSTGRDALAPGQERPYSTIRTKVYAILELWVQVCGASAGMLQGGASGEALLTHLLSDISPPADALKLCSTRGSSDGGLQSGKPSAPKKLKLDMGEALAPPSQRKGDRNADSDVCAAALRGLSRTILMCGPLVKEETHRRLHDLVLPLVMSVQQGEVLGSSPYNSSCCRLELYRLLLALLLAPSPRCPPPLSCALKAFSLGQWEDSLEVSSFCSEALVTCSALTHPRVPPLQSSGPACPTPAPVPPPEAPSSFRAPAFHTPGPMPSIGALPSPGPVPSAGPIPTVGSMSSAGSVPSTGPVPSRPGPPATANHLGLAVPGLVSVPPRLLPGSENHRAGSGEDPVLAPSGTPPPSIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPSLPPPPSGTPPPVAPIGPPTASPPVPAKEDSEELPATPGPLPPPPPPPPPVSGPVTLPPPQLVPEGTPGGGGPTAMEEDLTVININSSDEEEEEEEEEEEEDEDVEEEDFEEEEEDEEEYFEEEEEEEEFEEEFEEEEGELEEEEEEEEEELEEVEDVEFGSAGEVEEGGPPPPTLPPALPPTDSPKVQPEAEPEPGLLLEVEEPGAEDGPGPEIAPTLAPEVLPSQEEVEREGESPTAGPPQELVEEESSAPPTLLEEGTEGGGDKVPPPPETPAQEEMETETEASAPQGKEQDDTAAMLADFIDCPPDDEKPPPATEPDS
What is the function of this protein?
Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors.  Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner.  Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol.  Plays a role in E2-mediated cell cycle progression by interacting with RB1.  May have important functional implications in ER/growth factor cross-talk.  Interacts with several growth factor signaling components including EGFR and HRS.  Functions as the key stabilizing component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.  Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit.  Regulates pre-60S association of the critical remodeling factor MDN1.
What are the official names of this protein?
Proline-, glutamic acid- and leucine-rich protein 1, Modulator of non-genomic activity of estrogen receptor.
What is the protein family that this protein belongs to?
Belongs to the RIX1/PELP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Cytoplasm. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasm. Also found associated with the plasma membrane.
Protein: Y3144_BRUA2
Sequence: MKITWLGHAAFRVETAKAVILIDPFLNGNPGAKGIDFKEATRGVTHIALTHGHGDHVGDTVAIAREHGATVIANADLASWLGSQGVEKLDPGNTGGTLAHEGFTITFVNALHSSAMLTENGVSQALGNPNGLVFHFEDSPTLYHMGDTDIFSDMALINELHQPEIGIVPIGDRFTMGGAVAALACQRYFNFNSVLPCHYASFPIIDRTADKFIAGMADHPATKVLADPAGTVHSFQA
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BAB2_0644.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: SYP_XANOR
Sequence: MRLSQFHLHTTKETPADAELVSHRLMLRAGMIRKLASGLYTWSPLGLRVLRKVEAIVREEMDRAGAVEVLFPTIQPRELWDATGRWEKFGGQLLKIKDRKEQEFCYSPTAEEAAAEFARQEINSYKQLPLNFYQIQTKFRDEIRPRFGVMRAREFLMKDAYSFHLTDADMAREYDNMRAAYTRIFTRLGLDFRAVQADSGAIGGDASQEFHVIADSGEDSLAFSTGSDYAANVETASAALPAPRAAASEAMQQVATPTQKTCEDVAQLLGIALQRTVKSVAVMTEAGFVLALVRGDHAVNEIKLAKVPGLAGYRLANETEIRAHLGCEPGFLGPVNTARPVRVVADRDVAALADFVVGANVSGAHLVGVNWGRDLPEPETVADVRNVVEGERAADGGELRLARGIEVGHVFQLGSQYAQALQATVIDEGGKVAVMKMGCYGIGISRIVAAAIEQNHDDAGIIWPAPMAPWQVVVCVINPKQDAQVVSAAQALLDELIAAGLDAALDDRGLRPGAMFADMELLGIPHRVVVSERGLAAGTFEYRARTAAAAENLDKAGLFSRLGR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_DINSH
Sequence: MPLPDLSTLSADQPVLIAGPTASGKSALALRIAERQGGVIVNADALQVHHAWRVLTARPSPQDEARAPHRLYGHVARGTPHSVGHWLREVTPLLSGQRPIIVGGTGLFFTALTQGLSEIPEVPAEVRARADALREGDFARMQADLGARDPETSARIDMANPMRVQRAWEVLETTGRPLARWQADTPPPLLPRSRAARFVLEAPKDWLAPRIARRFRQMLDQGALDEARAALPHWDAAAPWARAIGAPELIAHLRGEITLDAAEEAATRATRQYAKRQRTWFRARMRDWTPVPPGSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL14_MICLC
Sequence: MIQQESRLKVADNTGAKEILTIRVLGGSGRRYAGIGDTIVATVKDAIPGGNVKKGDVVKAVVVRTRKQSRRPDGSYIKFDENAAVILKTDGEPRGTRIFGPVGRELRDKKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RS8_RALPJ
Sequence: MSMSDPIADMLTRIRNAQAVEKASVVMPSSKLKVAIAKVLKDEGYIDEFAVTEQGGKSTLTIGLKYYAGRPVIERLERVSKPGLRVYKGRNEIPQVMNGLGVAIISTPQGLMTDRRARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: KAD_CHLPB
Sequence: MRIILLGAPGAGKGTQAQFISSTFSIPQISTGDMLRAAINEGTPLGLEAKKVMDAGKLVSDEIILGLVKERLSKSDCKNGCLFDGFPRTIAQADALKNDCIQIDHVIDIEVDDEEIIKRMSGRRVHPASGRTYHVLFNPPAKEGVDDITGDPLVQREDDCEETVRKRLDIYHKETAPLIEYYREYKKNGGPNALKFSTIKGTGSVESIKEKILNIFHN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1188_SHESH
Sequence: MLVLVSPAKTLDYENKAGTIEHTLPKLVQHSEQLIEECRKLAPSDIASLMKVSDKIAGLNAARFTSWSRDFSTDNAKQALYAFRGDVYTGLDADTLSQQSIERAQKHLRILSGLYGLLRPLDLMQPYRLEMGTRLANIKGTNLYQFWGDVITDEVNLALSEQGDQIVVNLASNEYFKAVKPKSLNGSLITPIFKDRKNGQYKVISFFAKRARGMMVRYILDNNIKTFSGLTEFDAAGYYYCEAESTAQAPVFKREEQ
What are the official names of this protein?
UPF0246 protein Ssed_1188.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: GLMU_STRP4
Sequence: MSNFAIXLAAGKGTRMKSDLPKVLHKVAGIPMLEYVXRSVGAIXPXKTVTVVGHKAELVEEVLTGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGDTPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEXLRIVEQKDATDFEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLKDFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEANVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIAPVXLGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYATRLPHHPKNQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_PANGI
Sequence: MFSMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLEMDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMAVIDDYTTRTILNLPEIKNA
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: VM2_GLOBL
Sequence: EAGEECDCGSPGNPCCDAATCKLRQGAQCAEGLCCDQCRFMKKGTVCRIARGDDMDDYCNGISAGCPRNPF
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin halysin, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPA_YERPN
Sequence: MSKPIQMERGVKYRDADKMALIPVKNVVTERQELLRKPEWLKIKLPTDSSRIQGIKAAMRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIQDMGLRYVVITSVDRDDLRDGGAQHFADCISAIRAKNPTIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRVYRQVRPGANYDWSLKLLERFKEAHPDIPTKSGLMVGLGETNAEIVEVMHDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPAEFDEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_CHLTE
Sequence: MATSLQSVIVLDFGSQYTQLIARRIREIGIYSEIFPYHTKAETIRAHQPKAIILSGGPNSVYDEKAFMPDPEVFSLGVPVLGICYGLQAIAKHFGGNVESSSKQEFGRAKMLVNHDESESLLFRDIPDSDVWMSHGDKVTQLPEGFRVTASTANAEVCAIESFGSKAALKVYGLQFHPEVQHSLYGKQLLSNFLIDIAGITPDWSPKSFIQHQIEEIKRVAGDSTVVCGISGGVDSTVAAVLVSKAIGDKLHCVFVDNGLLRKDEAVKVMEFLKPLGLNISLVDASDLFLGRLKGVASPEKKRKIIGRTFIQVFEKNIHDEKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRVLGSLTRERLDVLRDADQIFIDELKSSGLYSKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLPHDFLAKVSNRIINEVRGINRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: EFG_THENN
Sequence: MQSVEARYVDLDKIRNIGIMAHIDAGKTTTTERILYYTGRKHFIGDVDEGTATTDWMPQEKERGITIQSAATTCFWKGYRINIIDTPGHVDFTAEVERALRVLDGAIAVFDATAGVEPQSETVWRQADKYNVPRIAFMNKMDKVGADFYMAVETLVTKLRANPIPIQMPIGSEKDFQGVIDLIKMKAIYWTSEDGSVYEEREIPDELKEEAELRREEMLEKVAELDETILEKYLEGEEITEEEIKKVLRKATIENRAVPVLCGAAKMNKGIQPLLDAVIDYLPSPLDLPPVKGWRLSDGEVVYRKPDENEPFTALVFKVQVDPYIGKLVYFRVYSGRLEKGSYVYNSTKGQRERISRIVFMHADKREEVDYVRPGDIAAGVGLKASQTGDTLCDEKEPTVLEKIDFPEPVISLAIEPATKSDEEKLVKALLALSEEDPTLQVKVDKETGETIISGMGELHLEIIVDRLKREFGVNVRVGQPQVAYRETIKKAAEAEGKYIRQTGGRGQYGHVILRIEPIPEEEGKNFEFIDKTVGGVIPKEFMPAIEAGIKEAMMSGPLAGYPVVRIRAIVLDGSYHEVDSSEMAFKIAASLAFKEAMKKAQPVLLEPIMKLEITTPEEYMGNIIADLNSRRAKVEALETRGHLKVIVAKVPLSETFGYATTLRSLSQGRASYIMQFSHYQEVPEKIAEKIIKVV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRO4_ARATH
Sequence: MGNMRSLVKTLMVVLFLGWILVWIMISTNLFKSKWTPKLSKYLNTTYFGPQGTNLVLLTVPMMFIAVLSCVYLHIQKKPTQPQREWKLKRIMGRVIMVMNPLGIVTATELTFSLLFVALLAWSLYNYLYLSYHVHLHNDDNAKIWQAKFRAFGLRIGYVGNICWAFLFFPVTRASTILPLVGLTSESSIKYHIWLGHVSNFCFLVHTVVFLIYWAMINKLMETFAWNPTYVPNLAGTIAMVIGIAMWVTSLPSFRRKKFEIFFYTHHLYGLYIVFYVIHVGDSWFCMILPNIFLFFIDRYLRFLQSTKRSRLVSARILPSDNLELTFSKTPGLHYTPTSILFLHVPSISKIQWHPFTITSSSNLEKDTLSVVIRRQGSWTQKLYTHLSSSIDSLEVSTEGPYGPNSFDVSRHNSLILVSGGSGITPFISVIRELISQSQNKSTKLPDVLLVCSFKHYHDLAFLDLIFPLDMSASDISRLNLRIEAYITREDKKPETTDDHRLLQTKWFKPQPLDSPISPVLGPNNFLWLGVVILSSFVMFLLLIGIVTRYYIYPVDHNTGSIYNFSYRGLWDMFLGSACIFISSSVVFLWRKKQNKEGDKEFKNQVQSVEFQTPTSSPGSWFHGHERELESVPYQSIVQATSVHFGSKPNLKKILLEAEGSEDVGVMVCGPRKMRHEVAKICSSGLAKNLHFEAISFNW
What is the function of this protein?
Ferric chelate reductase.  May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates (PubMed:16006655).  May function as root surface cupric chelate reductase and participate in the reduction of Cu(2+), for Cu(+) acquisition via Cu(+) transporters in response to copper deficiency (PubMed:22374396).
What are the official names of this protein?
Ferric reduction oxidase 4, AtFRO4, Ferric-chelate reductase 4.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UVRB_ALISL
Sequence: MTSAYELVSDYQPAGDQPQAIKTLNEGLENGLAHQTLLGVTGSGKTFTLANVIAKSGRPTVIMAHNKTLAAQLYGEMKAFFPNNAVEYFVSYFDYYQPEAYVPTTDTFIEKDSSVNEHIEQMRLSATKALLERKDAIIIASVSAIYGLGDPQAYLSMMLHLSRGDIINQRDILRRLAELQYKRNDMAFERGTFRVRGEVLDVFPAESEHEAIRIELFDDEVERISKFDPLTGSIITKDMPRCTIYPKTHYVTPREKVLDAIEQIKVDLAERKKELLANNKLVEEQRISQRTQFDIEMMNELGFCSGIENYSRYLSGRPQGEAPPTLFDYLPKDGLLIIDESHITVSQIGAMYKGDRSRKENLVEYGFRLPSALDNRPMRFDEFEARAPQTIYVSATPGKYEIEKSGSDIAEQLVRPTGLLDPIIEVRPVGTQVDDLLSEIRIRTKVGERVLVTTLTKRMSEDLTEYLAEHGVKVRYLHSDIDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQAIGRAARNLEGKAILYADRITGSMEKAIGETERRREKQILHNEALGIVPTALKKNVADILELGDMTKNKRKIVAPKMKLSEVAEEGASYQSMTPQQLEKEVQRLEAKMYQHARDLEFEQAAKVRDEVEKLRNQFITNS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA1_RHOBA
Sequence: MASKSSRSQEHIRNFCIIAHIDHGKSTLADRLLESTGTVDNRGKKTQMLDDLALEQQRGITIKARAVAMRYKRDGIEYELNLIDTPGHVDFQYEVSRSLACCEGALLLVDAFQGVEAQTVANAFAAMEHDLTIVPVINKIDLIHARPDEVAEEMMNSLGTDPDECKRVSAKTGEGVAALLDAIVDSVPAPTGDPKAVLQAMVFDSNYDDFRGAITYIRVMQGTVRKGQKIKFLRAGSVHDVVELGQFAPSRVPCDELVAGQVGYLICNIKSLGDVHIGDTISIAGNDPAPALPGYDRPKRMVYCGLFPSDGQDFSELRDALERLAVNDPSFEFEPETSDALGFGFRCGFLGLLHMEIVQQRLEQESDIDLVQTAPNVTYEITDKRGVTKNIHKPQDVPDPGDIEKFCQPIVRCNVIVPEEYIGPVMKLCQERRGIQKGHEVLGASRAMLTYDIPLAEVIYDLHDRIKSCTRGYGTLDYEMVGYEEADLCRLDILVNGNRVDALSVVCHRADADRRGRAVAKKLKSEIERHMFEVAVQAAIGSRVIARETVPAMRKNVTAKCYGGDITRKRKLLQKQKEGKKRMKAVGNVEISQKAFMAVLTDGE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4 1, EF-4 1, Ribosomal back-translocase LepA 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TAL_BURTA
Sequence: MTTALDQLKQYTTVVADTGDFQQLAQYKPQDATTNPSLILKAVQKDAYRPILEKTVRDHAGESVGFIIDRLLIAFGTEILKLIPGRVSTEVDARLSFDTQRSIDKGREIIKLYEAAGIGRERVLIKLASTWEGIRAAEVLQREGIRCNMTLLFSLVQAAACAEAGAQLISPFVGRIYDWYKKQKGAEWDEAKDGGANDPGVQSVRRIYTYYKQFGYATEVMGASFRTTSQITELAGCDLLTISPDLLQKLHDSAETVARKLSPDAAKDAQLERVAIDESSFRFQLNDDAMATEKLAEGIRLFSADAVKLEKMIDALR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_MARMM
Sequence: MSKRDFYEVLGVDKTADEKTLKSAYRKQAMKYHPDRNPGDAEAEAQFKVVGEAYSVLSDPNKRAAYDRMGHAAFEQGGGMGGGQGPFGGGGGAADFADIFEQVFGEAFNMGGGGGRRGGRGQAGPARGSDLRFDMEISLEDAFNGKDETIKVPTAMNCERCDGQGNEPGTELETCGTCQGAGRIRRSQGFFTMEQTCPQCGGRGQYVKTPCNDCDGVGRVRKTRTLNVTVPAGVEDGTRIRLAGEGEAGARGGPRGDLYIFISVREHEIFERDGPNLYCRTPASMVQAALGCTIQVPTIEGGKAEMKIAEGAQTGKRMRMRGKGMPRLRGGPRGDMIVELFVETPRNLCDRQKELLKEFCDLSGEGCNPDSAGFFNKVKQFWDEVTTDDGRPNAG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAP2_THET8
Sequence: MKKRLVTLLAGLLTVLSMGFGLAQFSDVPAGHWAKEAVEALAAKGIILGFPDGTFRGNENLTRYQAALLIYRLLQQIEEELKTQGTSPTMEALAPEDLEAMIAELKAQPMPEPGMDQAALKDLMDRVEAASIAADTALAQAQQLAERLDALAQDVEGVKGDLAGLRSQVEANADAIQALNELAVLLNQDVLSLQDRVTALEKMVSGGQELPDLEQFATKEDVAAVQEFAAALRSDLVGLSEKVSKLEGTVGDLSGKVATLQRNAFTISGSLSLNYSVYRAWGPDASAAGPGTANTFDIDRLFSSKFSTGDGNGNGSVGDEADLGKNTEGVTNATLSVSFSTGKLDAASDPGKLNSYPGLVQFSLRAKLTNPGKYDPSTGAPTYPINLTLDEFSSTLAVAKDQTLSFSFGRSVRSKFTEYVFDNDYNSRGHGFVATYKPGLLGATLTGVYGSKGANNGDFTYFRGARLALSPVEGIALGGSFVQEGLDANQGTTSASFPAPTTVYGVDASVKLGPVGLAGEYFNSDAAPNANGYYVKADVALGSISVAGNYRNIGAGVTGANMLSGDATSTLDQGGWGGVDSSGNVINGAPFRSNRQGFGVSASAGLGPITVKGYYDSSTVLANETITNSYGAFNYSANNQLVAYGGQADLAFGGFTLSGFYRIAQLNGSTTRYILTEKPAEAVYASEYGAKLAHDGASKDALVPKLNFTAAYTQKYDNATSGFTTQDIAVYGSYELALGPLTLKPMGRYHTQDAAAASTSSDYTTVKYGVAASIALDLPFKPSLSGEYYARSTQVTSANSGSSATGTISESKYAVGLKLGEFLFKNSSVEAKYASYTGSGLNAPILLGVADAASSTTSDYLYNNAVSSVGSNRGSVTGWYFTWTYWDLTFAYVEADVNNNGNQTHGQAFKISYTVKF
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein, P100 protein, Surface layer protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S-layer with hexagonal symmetry.
Protein: RL13_VIBC3
Sequence: MKTFVAKPETVKRDWYVVDAEGKTLGRLASEIASRLRGKHKAEYTPHVDTGDYIIVVNAEKVTVTGNKAKNKMYHRHSEFPGGLKSFSFEKLIERKPEMVLELAVKGMLPKGPLGRAMYRKLKVYAGAEHNHAAQQPKVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PDRP_BARHE
Sequence: MKREKKSFHLHMLSDATGETLISVGRAVASQYTMSQATEHIYPMIRNKTQLQRALDEIQQEPGIVLYTIIDKKIKILLRKRCEKIEIPCIDILHPVLNAFKSYLGIPTNLRVSAQHGLNADYFRRIEALDFTIEHDDGQSPNSLSDADVILVGISRTSKTPTSIYLANRGIKTANVPLIPGINLPDTLLGAKNALIIGLIASVERISHIRQNRNLGDDFSLESYTDRINISEELTYAKRICERFSWPVIDVTRRSIEETAAEIFELLSRFREGK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.