PharMolix/UniProtQA huggingface dataset:
Protein: ATG2_VANPO
Sequence: MPFWLASNLQKKLLLYILQKISLFSNVDLSNVDVSLGSNSKFAFHDVRLNCDDIDLPNIEVKESTIQQLDLQLTVSGVLNISGESVIIVVKPKVDNESNSSKEFSLAKSLHDLTASMIQFPQSFDLDEIKNMKTNQNEYDNDIIGSSSSSGNENDIDIYNSSSDEKNEKESESTGTMKSMKNKILSSVLSKFKMELKDVILKVILQDSAYIEISIDKVSLANKPDDIRTLIIDQVRIDHVKSIVEEQEISFNRRMPNNLEQSKSLYESNSLYMSALDEIQHNPEIDLKEDRLELLVVKHSNITLTGLSTIENFNLKDLDITVDHILCSYKNLLCIDEMFFDDVMGTLNSFISNSNNSPRSSTAYKRFQIENDLYENDRKLKLSINTIIFLVDDHISVSLSNFNLDQSEKNEFKINLELMKLNDLTTDRSMVFSPFLEAFISNSVLTLNFLSDLDFYFEKDFIIGLISVCQKTSKLMNTYNRKKNANKRPREPGRNNIKFSITTKNVSFKFKLDQSYILIRCDPIIYDWKTDKLAISKIEFLNDLNLQKLERFITVDSLILKFSNTPIQCLAYDEHFTKCALITKVLLNIKNICFRYQYHKLLQLYGSILEIIDEATRFEKSKKLSKRGSHLRNTVRIMNSSSIIFKKKLNANTIISIDNIDAQFDHFLNEEFGKMVLGLKNNLIALKENSEVYMLSKTLSIDRLLKERRYPILSCLLNSNSQEPTLIFEKKVRNKLKIYIKNVCLHYYARLLPILTKMDTDLKKENSDADHNSLFIDIKISNTAVVLHPFRIKPALIVIFDSLSISSDFLKCTHKIFFKHGCLLLIDDIGNMKVSSKQPWSSLSNYYLQRGFSAIGKITNTNVNIKTDCNGVEATTNVESLGLSLCADSFNTLISLLIDLKIPITFPDEDKYNIEVPEDVDVFADVDMSFFDPIHIKETEELIIGGESVHVVNEFLDDFHDEVEISEKVASPKKFFNDYISSHRITQPLELEESYIDRVDLDTTLEFTEMEFTAFNLDIKKISIKLFDGYDWKYTRKSISNTIDMVGREIEDYEADDDQNQPLHATIFDSIYISTTKSDVSNLKSRVNNEIQGESNPTGFIPKVNLKPSKYFKTLIELNNVNINFTGYPNQELVESRSKDTSTILSNIKVVVDTFEVIDNMPTSTWKKFITLYRHDKWPTGLPMFASEFSLVQPINSLQATEMIMALNISPLRLHIDQDTLDFLLRFFEFRDVRFELIDDFPEVLFIQKFTMNSVKILLDYKPKKINYSGLRSGHSSEFVNFFILDGAKLTLKNLKLYGINGFEDLSDSLKNVWTPDIISSQLGGIIGGVSPLKSAITIGTSVKKLVSVPITDYKQDGKLSRSIPKAVNIFLKTASGDFVRLGAKMASGTQAMLENTEEFFGGTGSAGRTFAIPEKFLDINNLVEEDQLVGGSNPKVKNHRPVAVVIDASKMELGQPKIVSLYADQPLDVREGLEEAYHSLERHLFIAYNSIKNRSTNMDVLESPTMTVLSMAKAAPIAIIRPLIGATEALSKALQGISNQLDKNQIENNKDKYKSTTIIDRKLVE
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: IQD4_ARATH
Sequence: MGKNWLTCVSVACLSPGKDKKNQKPEKPKRKWSFGKQKSRESFDFPLEETPPVDPSPSSVHRPYPPPPPLPDFAPQPLLPPPSPPPPPPAYTINTRIYGESKESKNRQALALASAVAAEAAVVAAHAAAEVIRLTTPSTPQIEESKEETAAIKIQNAYRCYTARRTLRALRGMARLKSLLQGKYVKRQMNAMLSSMQTLTRLQTQIQERRNRLSAENKTRHRLIQQKGHQKENHQNLVTAGNFDSSNKSKEQIVARSVNRKEASVRRERALAYAYSHQQTWRNSSKLPHQTLMDTNTTDWGWSWLERWMASRPWDAESIDDQVSVKSSLKRENSIKSSPARSKTQKSASQSSIQWPVNNDTKSRKIEVTNRRHSIGGGSSENAKDDESVGSSSSRRNSLDNTQTVKSKVSVETTSNVSNAQTVKPKANVGAKRNLDNTKTLKSKSSVGTTGNLANTEAVKSKVNVGTTSMPKKEVVADKKKPPQMVLPKKRLSSSTSLGKTKKLSDSDKATTGVANGEKKRRNGGSS
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 4, AtIQD4.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: RL24_BRUSI
Sequence: MQKIRKGDSVVVLSGKDKGRKGEVLKVMPKDEQALVSGINIVKRHQRQTQTQEAGIISKEAPIHLSNLAIADPKDGKPTRVGFRVEDGKKVRVAKRSGALIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MDTB_SALEP
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYRKLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS1_I67A2
Sequence: MDSNTVSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLRGRGSTLGLNIETATLAGKQIVEWILKEESNETLKMTIASVPSSRYLADMTLEEMSRDWFMLMPKQKVAGSLYIRMDQAIMEKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAVEVLIGGLEWNGNTVRVSENLQRFAWRSRNENGRPSLPPEQK
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: DGTL1_MYCUA
Sequence: MSTKQQEPYGDFDRQRRVVEAPKTAGLPGTEGQHRTDFARDRARVLHCAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELAGLAHDIGHPPYGHNGERALDEVAIGCGGFEGNAQNFRILTSLEPKVLDEHGLSVGLNLTRAALDAVTKYPWPRGRARRKFGFYDQDLQPALWVRQGAPQRRPCLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLADHDEAAALAKLGESEFSRVSADELMEAAGRLSGLPVVAAVGKYDATLAASVALKQLTSELVGRFASAAIATTRAAAGPGPLVRYQADLHVPELVRAEVAVLKILALQFIMSDPRHLETQARQRERIHRVAQLLYAGAPRTLDPIFAAAFNAAGDDGARMRVVVDQIASYTEGRLERIDAAQLGDGRVG
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: PNP_SALPB
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNFA_CEREL
Sequence: MIRDVELAEEALSKKAGGPQGSRSCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQSPTGLSINSPLVQTLRSSSQASINKPVAHVVANINAQGQLLWLDSCANALMANGVKLEDNQLVVPTDGLYLIYSQVLFRGQSCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETPEWAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDYAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: PYRG_HELHP
Sequence: MAVKYIFVTGGVLSSLGKGITSSSIATLLQQSGYSVSILKIDPYINVDPGTMSPLEHGEVFVTCDGAETDLDIGHYERFLNKDFHKKNNFTTGQIYMSVIENERKGKYLGKTIQIVPHIVDEIKSRIKFAGEGSDFLVVELGGTVGDIEGMPYLEAMRQMKHELGGKQVISIHITLIPLMRAAGELKTKPTQHSVQELRRIGISPQILVARCEKNLDKELKRKLALSCDVDNDSVIVAQDTQSIYKCPLNFLEEGILTPIARHLELGELKPKMDNWDMLVKKIIAPKSNITIGFVGKYLSLKESYKSLIESLIHAGANTDTRVNIKWIDSEILVDNLALLYDVDSLLIPGGFGERGIEGKLEAIKYARIQQIPLLGICLGMQLSLIEFARNVLGMSEANSIEFDPQTKEPVIYLIENFIDSQGGVQLRTHTSPMGGTMRLGEYECHIKKGTKLYEAYGKQTLIKERHRHRYEANPHYRALFEKNGMIVSGESNGLIESIELANHPWFVGVQFHPEFTSRLQNPNPVILAFVKETLAHKKT
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ATPE_ORYSA
Sequence: MKLNLYVLTPKRIIWDCEVKEIILSTNSGQIGVLPNHAPINTAVDMGPLRIRLLNDQWLTAVLWSGFARIVNNEIIILGNDAELGSDIDPEEAQQALEIAEANVSRAEGTKELVEAKVALRRARIRVEAVNWIPPSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ISDH_STAA8
Sequence: MNKHHPKLRSFYSIRKSTLGVASVIVSTLFLITSQHQAQAAENTNTSDKISENQNNNATTTQPPKDTNQTQPATQPANTAKNYPAADESLKDAIKDPALENKEHDIGPREQVNFQLLDKNNETQYYHFFSIKDPADVYYTKKKAEVELDINTASTWKKFEVYENNQKLPVRLVSYSPVPEDHAYIRFPVSDGTQELKIVSSTQIDDGEETNYDYTKLVFAKPIYNDPSLVKSDTNDAVVTNDQSSSVASNQTNTNTSNQNISTINNANNQPQATTNMSQPAQPKSSTNADQASSQPAHETNSNGNTNDKTNESSNQSDVNQQYPPADESLQDAIKNPAIIDKEHTADNWRPIDFQMKNDKGERQFYHYASTVEPATVIFTKTGPIIELGLKTASTWKKFEVYEGDKKLPVELVSYDSDKDYAYIRFPVSNGTREVKIVSSIEYGENIHEDYDYTLMVFAQPITNNPDDYVDEETYNLQKLLAPYHKAKTLERQVYELEKLQEKLPEKYKAEYKKKLDQTRVELADQVKSAVTEFENVTPTNDQLTDLQEAHFVVFESEENSESVMDGFVEHPFYTATLNGQKYVVMKTKDDSYWKDLIVEGKRVTTVSKDPKNNSRTLIFPYIPDKAVYNAIVKVVVANIGYEGQYHVRIINQDINTKDDDTSQNNTSEPLNVQTGQEGKVADTDVAENSSTATNPKDASDKADVIEPESDVVKDADNNIDKDVQHDVDHLSDMSDNNHFDKYDLKEMDTQIAKDTDRNVDKDADNSVGMSSNVDTDKDSNKNKDKVIQLNHIADKNNHTGKAAKLDVVKQNYNNTDKVTDKKTTEHLPSDIHKTVDKTVKTKEKAGTPSKENKLSQSKMLPKTGETTSSQSWWGLYALLGMLALFIPKFRKESK
What is the function of this protein?
Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin.  Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone.
What are the official names of this protein?
Iron-regulated surface determinant protein H, Haptoglobin receptor A, Staphylococcus aureus surface protein I.
What is the protein family that this protein belongs to?
Belongs to the IsdH family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor.
Protein: MIAB_FRATF
Sequence: MKEQKKVFIKTLGCQMNEYDSARMHEVLNEHFDTVKTDDYKDADIILINTCSIREKAQEKVFHELGRWKGLKKTNEDLIIGVGGCVASQEGENIIKRAPFVDLVFGPQTIHRLPEMIKQKQKSQQSQVDISFPEVEKFDYLPEPKAEGAKAYVSIMEGCDKYCSYCVVPYTRGPEVNRPFEDVLAECAILAEQGVKEITLLGQNVNHYLGPMENGQTADLALLIHFIAEIDGIERIRFTTSHPVEFSQNLIDAYATVPELANHLHLPVQHGSDRILINMKRNHTILEFKQKIRKLRAIRPDITISSDFIVGFPGETEEDFQKLLDLVKEINFDQSFSFIYSKRPGTPAADLPDDTPMEVKKDRLKRLQDLLNSNAQIISRQMVGTNQRILVDGTSKKDDNILSGRTENNRVVNFKGDKSLIGQFAMVKITESLPNSLRGELI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SHEDO
Sequence: MRPPISKSWPAPAKLNLFLHVTGQRDDGYHELQTLFQFIDHCDYLDFQVNLCGEIKLHSELSKVVADKDNLILQAAKSLQKHAGVTQGADIWLEKLLPMGGGLGGGSSDAATTLVALNALWNINYHVDILAEIGLKLGADVPVFIHGLASFAEGVGEQLKPVLPAEKWYLVLVPNVHVSTQAIFQSPELTRNTPKLSLSNLMSQHWSNDCEKLVIAHYPQVANALSWLVEYAPSRMTGTGACVFGEFEQEQQALAVLAELPPNMTGFVAKGMNRSPLLERLANA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: IAMT1_ARATH
Sequence: MGSKGDNVAVCNMKLERLLSMKGGKGQDSYANNSQAQAMHARSMLHLLEETLENVHLNSSASPPPFTAVDLGCSSGANTVHIIDFIVKHISKRFDAAGIDPPEFTAFFSDLPSNDFNTLFQLLPPLVSNTCMEECLAADGNRSYFVAGVPGSFYRRLFPARTIDFFHSAFSLHWLSQVPESVTDRRSAAYNRGRVFIHGAGEKTTTAYKRQFQADLAEFLRARAAEVKRGGAMFLVCLGRTSVDPTDQGGAGLLFGTHFQDAWDDLVREGLVAAEKRDGFNIPVYAPSLQDFKEVVDANGSFAIDKLVVYKGGSPLVVNEPDDASEVGRAFASSCRSVAGVLVEAHIGEELSNKLFSRVESRATSHAKDVLVNLQFFHIVASLSFT
What is the function of this protein?
Catalyzes the methylation of the free carboxyl end of the plant hormone indole-3-acetic acid (IAA).  Converts IAA to IAA methyl ester (MeIAA).  Regulates IAA activities by IAA methylation.  Methylation of IAA plays an important role in regulating plant development and auxin homeostasis.  Required for correct leaf pattern formation.  MeIAA seems to be an inactive form of IAA.
What are the official names of this protein?
Indole-3-acetate O-methyltransferase 1, IAA carboxylmethyltransferase 1, S-adenosyl-L-methionine:(indol-3-yl) acetate carboxylmethyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. SABATH family.
Protein: HEM1_STRMK
Sequence: MTLWVLGLNHQTAPVELRERAAFAGEALPRALGSLRDTPQIAEAVLLSTCNRTELYAVADSAQALDQWLHAQAGDLQGYLYQHADAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWSTARDHGLLGQRLDRLFQQTFSVAKRARTDTQVGANPVSVASAAVRLAQNAFARLDDSTVLLVGAGETIELAARHLSEGKVRRLLIANRTLAHAQELASRHGGVALPLTELDRHLGEADVVFSATAAREPVIHREMVAKALRARRHKPMLLFDLAVPRDIEAEVGTLNDAFLYTVDDLERAVEDNRRGRREAAAEAEAIIDLQVSRFIETQQASAHQAPLRQLRAFGEATRTELLERARQQLANGKPADEVLELLAHGLTNRLLHPPTAALRAAALSGDADLTRAAERLFPATPGYRHPPVRPDDADPAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MNMA_PSYWF
Sequence: MTTSTGFDNNAYNLPALRLSDVPNPAQTRVVVGMSGGVDSSVSAVLLQQAGFQVEGLFMKNWEEDDGTEYCTAMEDLADAQAVCDKIGINLHTANFAMEYWDRVFEHFLAEYQAGRTPNPDILCNKEIKFKAFLDYAVTLGADYIATGHYTRRSVNYTREDGLEVAHLMRGLDNNKDQSYFLHAVGGDKIAKTLFPVGELEKPEVRRIAEEHDLITAKKKDSTGICFIGERRFKDFLQQYLPAKPGNIVTDDGITIGKHDGLMYYTLGQRGGIGIGGVKDRPEEPWFVLQKDLSNNELIVGQGHDHPMLLSQRLTAYKLDWVERIAPAAIFSEQGLKCMAKTRYRQPDQSCTVFADSDDGSRVKVIFDEPQRAVTPGQSAVFYIGEVCLGGGVIESFE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT46_HUMAN
Sequence: MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS
What is the function of this protein?
Functions as a transcriptional repressor for PRDM1.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 46, BTB-ZF protein expressed in effector lymphocytes, BZEL, BTB/POZ domain-containing protein 4, Zinc finger protein 340.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRIX_METMP
Sequence: MIITTSRKPSQRTRSLVNDLARVFNFKILNRGKIPLSELIENKDDMIIVEELKGNPGRLKIFNFENNKILSMNLSLKLQREVSGKAFKNSGKLGSKFDKNTEHLKEFFFEYLFKKLSNYKEENFEVVITFKTVDESTFYIEVHKGSENMGPSLKIKTVKILDIE
What is the function of this protein?
Probably involved in the biogenesis of the ribosome.
What are the official names of this protein?
Probable Brix domain-containing ribosomal biogenesis protein.
Protein: PYRD_CHESB
Sequence: MMHIIDRLTRPVLFAFDPERAHELSIAALKTGIPFCSGGVQNSKLAVSVAGLNFPNPIGMAAGYDKNAEIPDALLNLGFGFAECGTVTPKPQEGNPRPRIFRLTRDRAVINRLGFNNEGHAQALARLSLRKGKSGIVGVNIGANRDSSDRMADYEEGVRTFAAVASYLTINISSPNTTGLRGLQDRENLSELLQRVMRVRNEQAALIKRKVPVFLKIAPDLSEEALADIAQEVLEKGLDGLIVSNTTLSREGVSAPAASETGGLSGEPLFERSTIVLAKMRRLVGPALPIIGVGGVHSAETALEKMRAGADLVQLYTGMVFAGPGLPARIVSRLAAYAEANGLNSIAEIRDSNIKPWADRPLA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CMTA6_ARATH
Sequence: MDGDGLGRLIGSEIHGFHTLQDLDVQTMLEEAKSRWLRPNEIHAILCGRIILFDRKMLRNFRKDGHNWKKKKDGRTVKEAHEHLKVGNEERIHVYYAHGEDNTTFVRRCYWLLDKARENIVLVHYRDTQEAATTSGDSISSPISVSEQTFPNRVAAEDIDTVVRNHDISLHDINTLDWDELLVPTDLNNQSAPTVDNLSYFTEPLQNAANGTAEHGNATVADGSLDALLNDGPQSRESFGRWMNSFISESNGSLEDPSFEPMVMPRQDPLAPQAVFHSHSNIPEQVFNITDVSPAWAYSSEKTKILVTGFLHDSYQHLERSNLYCVCGDFCVPAEYLQAGVYRCIIPPHSPGMVNLYLSADGHKPISQCFRFEHRAVPVLDKTVPEDNQDSKWEEFEFQVRLSHLLFTSSNKLNVLSSKISPHNLRDAKKLASKTNHLLNSWAYLVKSIQGNKVSFDQAKDHLFELSLKNRLKEWLMEKVLEGRNTLDYDSKGLGVIHLCASLGYTWSVQLFSLSGLSLNFRDKQGWTALHWAAYYGREKMVAALLSAGARPNLVTDSTKDNLGGCMAADLAQQNGYDGLAAYLAEKCLVAQFRDMKIAGNITGDLEACKAEMLNQGTLPEDEQSLKDALAAYRTAAEAAARIQGAFREKALKAARSSVIQFANKEEEAKSIIAAMKIQNAFRKYDTRRKIEAAYRIQCRFQTWKIRREYLNMRRQAIRIQAAFRGLQARRQYKKILWSVGVLEKAVLRWRQKRKGFRGLQVAAEEDSPGEAQEDFYKTSQRQAEERLERSVVRVQAMFRSKKAQQDYRRMKLTHEEAQVNHLTFLNLSFGKKNSNRR
What is the function of this protein?
Transcription activator that binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065).  Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity).  Regulates transcriptional activity in response to calcium signals (Probable).
What are the official names of this protein?
Calmodulin-binding transcription activator 6, AtCAMTA6, Ethylene-induced calmodulin-binding protein 5, EICBP5, Ethylene-induced calmodulin-binding protein e, EICBP.e, Signal-responsive protein 3, AtSR3.
What is the protein family that this protein belongs to?
Belongs to the CAMTA family.
Protein: AZOR_ACISJ
Sequence: MQLLHIDSAITGDQSVSRQLTAQTVEAWKASHPATQVSYLDLVADAPAHFTMDAMAPRTGQTDGLSEAQQRENAVSERLVSQFLAADVVVIGAPFYNFAIPTQLKAWIDRIAQPGRTFQYTANGPEGLAKGKTVIVASSRGGVYSTSEGGRAMEHQESYLQTVLGFFGVTDVRFVRAEGVAMGGDAKAQALAAAAQAIEAHVKAHAANQDRVSQAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: APK4_ARATH
Sequence: MDVAAMARCVGRCYVSPAFGESESHRLSERRFLKLSSSTNSDPAGSKSLKLRGKIHRRMSYFRPIMAKDESISSRSGETKQINGKQKNIVWHDCPVTKSDRQELIKQKGCVIWITGLSGSGKSSLACALSRALHNRGKLSYILDGDNVRHGLNSDLSFEADDRAENIRRVGEVAKLFADSGIICIASLISPYRIERAACRALLPQGDFIEVFMDVPLHVCEARDPKGLYKRARAGKIKGFTGVDDPYEAPLDCEIVIQNSRDKGLSSSSSSSSSPSSSSSSLCEMADIVVSYLDQNGYLKKHSTKSRNCM
What is the function of this protein?
Catalyzes the phosphorylation of adenosine 5'-phosphosulfate to 3'-phosphoadenylyl sulfate, which is the activated sulfate form for sulfation reactions.  Essential for plant reproduction and viability.
What are the official names of this protein?
Adenylyl-sulfate kinase 4, chloroplastic, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase 4, Adenosine-5'-phosphosulfate kinase 4, APS kinase 4.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YHHJ_SHIFL
Sequence: MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTPGSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIPPNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVSLETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPFEIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA
What are the official names of this protein?
Inner membrane transport permease YhhJ.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.