PharMolix/UniProtQA huggingface dataset:
Protein: TRMA_COLP3
Sequence: MFSHIHPDNYDAQLSKKQQDMAKLFSDFNLPAPDLYPSVPLNYRQRAEFRVWHEGDDLYYIMFDSKTKEKFRVDDFPVASELINNAMKALLATIKDQRELRFKLFQVDFLSTLSGELLISMLYHKPLEDNWQIEAEKLKAQLSTIAPVDIIGRAKKQKIIVDKDYVMESLNVGGKTYVYQQVENSFTQPNAGVNEQMLLWAQQATQNAGGDLIELYCGNGNFSIALAENFERVLGTEISKTSVRSAQINISENGIDNIDIVRMSSEEFSQAMNGERKFRRLEDFDLTTYNYDTVLVDPPRAGLDRDSVELVRRFNKIIYISCNPETLKDNLALLVETHQIDKFALFDQFPYTDHIETGVILTRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RS3_DESAL
Sequence: MGQKVNPIGLRLGIVKTWDSRWYAEKGKYAEFIREDFKLRKFLKKKLHHAGISKIEIERSGRRVRLRVFAARPGIVIGKKGSEIEQLKKELEKMVDNEVLIDIQEVRKPELDAQLVAENVAMQLERRVAFRRAMKRGISSAMRFGAQGVKIMAAGRLGGAEMARREWYREGRMPLHTLRADIDYGYTEANTTYGVIGVKVFIFKGEILKSDTEAANPTA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EPSO_BACSU
Sequence: MDSKHSMISLKQKLSGLLDVIPKQSEIIYADYPLYGNVGDLFIMKGTEAFFKEHGIRVRKRWNPDNFPIGRKLDPNLIIVCQGGGNFGDLYPYYQGFREKIVQTYPNHKIVILPQSIYFQNKDNLKRTAEIFSKHANLHIMTREKASYATAQAYFTTNHIQLLPDMAHQLFPVIPTQQPSNQKLRFIRTDHEANQALQEHAEAESYDWRTVLSASDRRTIAFLQTLNVLNKKAGNPLPIAYIWEKYSDYIVQKAIRFFSRYESVETSRLHGHILSSLLQKENTVIDNSYGKNANYFHTWMEGVPSTRLIQHASKKENLPAHM
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.
What are the official names of this protein?
Putative pyruvyl transferase EpsO.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: CDC6_THEON
Sequence: MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSNVFVYGKTGTGKTVTIKFVTEELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREESGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKLIKKSGDDILYSLTRINTELHRAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLDDGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVLLDENGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQLQTVLTISMSRQRRLL
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: RUVC_VIBC3
Sequence: MSVILGIDPGSRVTGYGVIRQQGRHLIYLGSGCIRTSDLELPLRLKQIYAGVSEIITQFQPDAFAIEQVFMAKNADSALKLGQARGSAIVAAVNAELPVYEYAARLIKQAVVGTGAADKSQVQHMVQQMLKLPGKPQADAADALGVAICHANTNKTLIALAGQATSARRGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: FOLD_MICAN
Sequence: MSVTTCQILDGKALAQKIQLGLGERIQTLKSPMGRPPGLAVLMVGDNPASAVYVRNKEKACTKIGMASFGRHFSTDTSELEILAEIVRLNQDERVDGILIQLPLPKHLDAVSLLYQIDPKKDADGLHPLNLGGLVRGEDCIRSCTPAGVMALLKEYNIPIAGKHAVVVGRSILVGKPLALMLLEENATVTIAHSRTENLAEITRSADILVPAVGKANLITKDMVKPGAVVVDVGINRVADRLVGDVDYAGVLEVASYLTPVPGGVGPMTVAMLLKNTLLSYERKL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EFTS_ECOHS
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHB2_STAAR
Sequence: MKENDVVLRTVTKLVVFILLTFGFYVFFAGHNNPGGGFIGGLIFSSAFILMFLAFNVEEVLESLPIDFRILMIIGALVSSITAIMPTFFGKPFLSQYETTLTLPILGHIHVTTITLFELGILFSVVGVIVTVMLSLSGGRS
What are the official names of this protein?
Putative antiporter subunit mnhB2, Mrp complex subunit B2, Putative NADH-ubiquinone oxidoreductase subunit mnhB2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRI44_MOUSE
Sequence: MASGVGAACEELPPDGTCDECEPDEAPGAEEVCRDCGFCYCRRHADAHRQKFLSHRLAAYVHGAQAWTPPASGGDDALPEDAEAKGEAEGEVESEVGEEESETEVDSESEEESETEEDSEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHRGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKIFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT
What is the function of this protein?
May play a role in the process of differentiation and maturation of neuronal cells (By similarity).  May regulate the activity of TRIM17 (By similarity).  Is a negative regulator of PAX6 expression (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 44, Protein DIPB, Protein Mc7.
Protein: COG2_MOUSE
Sequence: MEKRRMNLPTGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDRALNQLSVPLGQLREEVLSLRSSVSEGILAVDERMSKQEDIRKKKMSVLRLIQVIRSVEKIEKILNSQSSKDVSSQEASSPLLTGQVLERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSDVDIVRHCLRTYATIDKTQDAEALVGQVLVKPYVNEVIVEQFVESHPSSLQLMYNKLLEFVPHHCRLLREVTGGAVSSEKGTIVPGYDFLVNSVWPEIVRGLEEKLPSLFNPGDPDAFHQKYTVSMDFVQRFERQCGSQASVKRLRAHPAYHNFSNKWNLPVYFQIRFREVAGSLEAALTDGLEDAPAGSPYCLLASHRTWISLGKCWSDEMFLPLLAHRLWRLTLQILARFSVFVSELSVRPVSNESAKETKKPLTGSKDPSEDQGSHASEASAASISSTQLVYVVSDLGRLQEWLPDLLETVKQKLEMIGFKNFSSISAALEDSQSALSAHVPALSSRIVQDLSESCFSYLKSALEVPRLYRRTNKEVPSTASSYVDSALKPLYQLQSGHGDKVQPAVMQSWLQEALSDSTHRYFETVSDVLNSVKKMEESLKRLKQARRSPATNPVSSSGGGMSDDDKIRLQLALDVEHLGEQIQRMGLQTSDIKSFPALMELVLAARDQAAAEQP
What is the function of this protein?
Required for normal Golgi morphology and function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein.
What is the protein family that this protein belongs to?
Belongs to the COG2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SHEP_DROAN
Sequence: MHPRYSPAPPPQQHQGPQMGGPHPHQGGVSGGGGGGIGNMRGSGNMQQLPPQIPRSQNYSTGSSSSAAAAPPTPRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTAQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCYGFVDFEQPAFAECAVKGLQGKGVQAQMAKVGIWVLHRPAIQQEQDPTNLYIANLPPHYKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIPGGKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDPTLQQNGVSVNVGTPIGVPYSRFSAPQVGGYPVAGSQWIPGYMMTQPITQVDDQYMQMAAAPQLGVTSYKPEAVNQVQPRGISMMVSGDTAVPYGTMMPQLATLQIGNSNFSPSLQYISPTYPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK
What is the function of this protein?
Has a role in the perception of gravity.
What are the official names of this protein?
Protein alan shepard.
Protein: ADML_RAT
Sequence: MKLVSIALMLLGSLAVLGADTARLDTSSQFRKKWNKWALSRGKRELQASSSYPTGLVDEKTVPTQTLGLQDKQSTSSTPQASTQSTAHIRVKRYRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGYGRRRRRSLPEVLRARTVESSQEQTHSAPASPAHQDISRVSRL
What is the function of this protein?
AM and PAMP are potent hypotensive and vasodilatator agents.
What are the official names of this protein?
Pro-adrenomedullin.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: E434_ADE02
Sequence: MTTSGVPFGMTLRPTRSRLSRRTPYSRDRLPPFETETRATILEDHPLLPECNTLTMHNVSYVRGLPCSVGFTLIQEWVVPWDMVLTREELVILRKCMHVCLCCANIDIMTSMMIHGYESWALHCHCSSPGSLQCIAGGQVLASWFRMVVDGAMFNQRFIWYREVVNYNMPKEVMFMSSVFMRGRHLIYLRLWYDGHVGSVVPAMSFGYSALHCGILNNIVVLCCSYCADLSEIRVRCCARRTRRLMLRAVRIIAEETTAMLYSCRTERRRQQFIRALLQHHRPILMHDYDSTPM
What is the function of this protein?
Plays a major role to prevent cellular inhibition of viral genome replication by nuclear bodies.  Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E1B-55K.  This viral RING-type ligase ubiquitinates cellular substrates prior to proteasomal degradation: p53/TP53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.
What are the official names of this protein?
Early 4 ORF6 protein, E4-ORF6, Early 4 34 kDa protein, E4-34k.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E4 30 to 34 kDa protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Colocalizes with host PML-associated nuclear bodies.
Protein: CPSF1_ORYSJ
Sequence: MSYAAYKMMHWPTGVDHCAAGFVTHSPSDAAAFFTAATVGPGPEGDIDSAAAASRPRRLGPSPNLVVAAANVLEVYAVRAETAAEDGGGGTQPSSSSGAVLDGISGARLELVCYYRLHGNIESMTVLSDGAENRRATIALAFKDAKITCLEFDDAIHGLRTSSMHCFEGPEWQHLKRGRESFAWGPVIKADPLGRCGAALAYGLQMIILKAAQVGHSLVGEDEPTCALSSTAVCIESSYLIDLRALDMNHVKDFAFVHGYIEPVLVILHEQEPTWAGRILSKHHTCMISAFSISMTLKQHPVIWSAANLPHDAYQLLAVPPPISGVLVICANSIHYHSQSTSCSLDLNNFSSHPDGSPEISKSNFQVELDAAKATWLSNDIVMFSTKAGEMLLLTVVYDGRVVQRLDLMKSKASVLSSAVTSIGNSFFFLGSRLGDSLLVQFSYCASKSVLQDLTNERSADIEGDLPFSKRLKRIPSDVLQDVTSVEELSFQNIIAPNSLESAQKISYIVRDALINVGPLKDFSYGLRANADPNAMGNAKQSNYELVCCSGHGKNGSLSVLQQSIRPDLITEVELPSCRGIWTVYYKSYRGQMAEDNEYHAYLIISLENRTMVLETGDDLGEVTETVDYFVQASTIAAGNLFGRRRVIQVYGKGARVLDGSFMTQELNFTTHASESSSSEALGVACASIADPYVLLKMVDGSVQLLIGDYCTCTLSVNAPSIFISSSERIAACTLYRDRGPEPWLTKTRSDAWLSTGIAEAIDGNGTSSHDQSDIYCIICYESGKLEIFEVPSFRCVFSVENFISGEALLVDKFSQLIYEDSTKERYDCTKASLKKEAGDSIRIVELAMHRWSGQFSRPFLFGLLNDGTLLCYHAFSYEASESNVKRVPLSPQGSADHHNASDSRLRNLRFHRVSIDITSREDIPTLGRPRITTFNNVGGYEGLFLSGTRPAWVMVCRQRLRVHPQLCDGPIEAFTVLHNVNCSHGFIYVTSQGFLKICQLPSAYNYDSYWPVQKVPLHGTPHQVTYYAEQSLYPLIVSVPVVRPLNQVLSSMADQESVHHMDNDVTSTDALHKTYTVDEFEVRILELEKPGGHWETKSTIPMQLFENALTVRIVTLHNTTTKENETLLAIGTAYVLGEDVAARGRVLLFSFTKSENSQNLVTEVYSKESKGAVSAVASLQGHLLIASGPKITLNKWTGAELTAVAFYDAPLHVVSLNIVKNFVLFGDIHKSIYFLSWKEQGSQLSLLAKDFGSLDCFATEFLIDGSTLSLVASDSDKNVQIFYYAPKMVESWKGQKLLSRAEFHVGAHITKFLRLQMLPTQGLSSEKTNRFALLFGNLDGGIGCIAPIDELTFRRLQSLQRKLVDAVPHVCGLNPRSFRQFHSNGKGHRPGPDNIIDFELLCSYEMLSLDEQLDVAQQIGTTRSQILSNFSDISLGTSFL
What is the function of this protein?
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition.  This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
What are the official names of this protein?
Probable cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the CPSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y394_DEIRA
Sequence: MPDARRRPERQTAAVSFSARSFPALHSVLAPTALAGLVSETYGLTQPALTLLRRGLNDTSRVQSGERRTILRVYRCGWRTPAEVGWELAFLQHLAGRGVRVSSPLPRADGALFGVLDAAEGPRAYAMFEYLPGRALENTPADAALYGQCAAGLHDAADPFTAPGRLALDLNHLLTEPLRQMRPLLTEFPDLAAPLEAAAERTQARLTALAPGLSWGACHGDLHEANARLTPENEVGLFDFDCAGPGFRAYDLAVYWWSQVTQGQGAEEVQPLWDAFLGAYRERRPLTDADLAALPHFVAARALWFMGLMAGRAAEFGTETLGRPFFEFGLNFLTEWEERHGA
What are the official names of this protein?
Uncharacterized protein DR_0394.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: TPRA1_HUMAN
Sequence: MDTLEEVTWANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIFLLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDETEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCHTGSINSTDSERWKAINA
What are the official names of this protein?
Transmembrane protein adipocyte-associated 1, Integral membrane protein GPR175, Transmembrane protein 227.
What is the protein family that this protein belongs to?
Belongs to the UPF0359 family.
Protein: RL20_COREF
Sequence: MARVKRSVNAKKKRREILKSAKGYRGQRSRLYRKAKEQWLHSMTYAYRDRRARKGEFRKLWIQRINAAARMNGITYNRLIQGLRLAEIEVDRKILADLAVNDFAAFSAICEAAKAALPEDVNAPKAAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ANFD_AZOVI
Sequence: MPHHEFECSKVIPERKKHAVIKGKGETLADALPQGYLNTIPGSISERGCAYCGAKHVIGTPMKDVIHISHGPVGCTYDTWQTKRYISDNDNFQLKYTYATDVKEKHIVFGAEKLLKQNIIEAFKAFPQIKRMTIYQTCATALIGDDINAIAEEVMEEMPEVDIFVCNSPGFAGPSQSGGHHKINIAWINQKVGTVEPEITGDHVINYVGEYNIQGDQEVMVDYFKRMGIQVLSTFTGNGSYDGLRAMHRAHLNVLECARSAEYICNELRVRYGIPRLDIDGFGFKPLADSLRKIGMFFGIEDRAKAIIDEEVARWKPELDWYKERLMGKKVCLWPGGSKLWHWAHVIEEEMGLKVVSVYIKFGHQGDMEKGIARCGEGTLAIDDPNELEGLEALEMLKPDIILTGKRPGEVAKKVRVPYLNAHAYHNGPYKGFEGWVRFARDIYNAIYSPIHQLSGIDITKDNAPEWGNGFRTRQMLSDGNLSDAVRNSETLRQYTGGYDSVSKLREREYPAFERKVG
What is the function of this protein?
This iron-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.  Other nitrogenase complexes utilize a molybdenum-iron protein or a vanadium-iron protein.
What are the official names of this protein?
Nitrogenase iron-iron protein alpha chain, Dinitrogenase 3 subunit alpha, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: RASL_COLTR
Sequence: MASKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDEEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFEEITTFQQQILRVKDKDYFPMVVVGNKCDLEGEREVTRQEGEALAKSFGCKFIETSAKSRINVDKAFYDIVREIRRYNREMQGYSTGSGGASGINGPPKPMDVENGEQEAGCCSKCLIM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein, Ct-Ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: METK_SERP5
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRKTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRTDPLEQGAGDQGLMFGYATNETEVLMPAPVTYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEDISLKDLQEAVMEEIIKPVLPTEWLSAGTKYHINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKIPTEQLTLLVREFFDLRPYGLIQMMDLLQPIYRETAAYGHFGREHFPWEATDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCN1_CANGA
Sequence: MVSRHEKELMKTFQSLTSCTDEGKAKRYLSANNWNINYALNEYYDKEVGGFTEDHMIRHQFKYPDELVSLFGHYAALIEEDGTQSITPDGLIDYIQDLGYNLEDLVTISLAHFLQCKNLENPITEKQFLYFWYNEGCYTLEQMRHYLEDCERKLCNDWKYFTTIYNYSFDLNASKQGVVETDIAIEYWKLFFEENRTKLSGIIKVDQAHLDLWCKFLQDEHKKLIHKDTWQMLLLFFKKFPSLDAIKTEYNEADAWPYTIDEFYEYLEERNVL
What is the function of this protein?
May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes.  Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
What are the official names of this protein?
Defective in cullin neddylation protein 1.
Protein: CLPL_STAAS
Sequence: MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
What is the function of this protein?
Required for the development of induced thermotolerance.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpL.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpL subfamily.
Protein: VELC_MAGO7
Sequence: MPVHFNQSVGMPPARDGARPPPIKGGLMGKLIPATYSPNGRHPRIAPPPPPTPPAGAGAGAGAAPPQRQLLQHSPTTAPGPRRPSNPSSPQHPQQPGIDRFPQIIPYQHEQPQRRPSRQQYSASPPVDYSFGKGPKQSGLDQSSSTSSSVSPKQEMKQMSIHNLLSSGDQDDQDDKSINNSNTARASSASLASLASPRSVLPPAAMPSPSPSFSTSEYHLHVRQQPVAARSCGFGERDRRVIDPPPIVQMTIDDPSATPDQMQQRLRHPFSVVHCSIYNETGEEDNSAMPEDYRQQRRLMGTLVASPFVGKDENGEDGCFFCFPDLSCRTPGSFRLKFSLVVINPADMRQGLRTPIAATAMSDVLVVYNAKDFPGMQASTPLTRKLKEQGCLISIKKGNEKGGGGGGGGPSGSRDQYSDDEYDDDGGGGSGRAGKRKRIRRS
What is the function of this protein?
Velvet-domain-containing protein that acts as a positive regulator of sexual development (PubMed:24632440).  Plays an important role in pathogenicity through regulating positively appressorium-mediated penetration and invasive growth (PubMed:24632440).
What are the official names of this protein?
Sexual development regulator VELC.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelC subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRA5_ORYSJ
Sequence: MARGSAAAAIAGVVWVLLLLVGVASGARLPGGSGGNRGREPRGGAAAAAVATETAVFALGSFWRSEAAFGCLPGVIRTSVGYAGGSKARPEYRNLGDHAECVKVEYDPRLIQYKKLLEVFWASHDPREVFGQGPDVGNQYRSIIFTNGSVEARLAGLSKEKEQAKDRRSVITTQIQPIGAFYPAEPEHQKFELKRKPFLLQLIGNLPEEELLTSTLAAKLNAYAAELCSPNTQNRINSKIDEIAKKGWPILRDI
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRA family specifically reduces the MetSO S-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase A5, OsMSRA5, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RS27_THEON
Sequence: MALPKNLIPMPRSRFLRVKCIDCGNEQIVFSNPATTVRCLVCGATLVEPTGGKGVIKAKILEVLE
What are the official names of this protein?
30S ribosomal protein S27e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: DNLJ_SHESH
Sequence: MHAIQEEIKQLTSVLNEHNYRYYVDDAPSVPDAEYDRLINRLKQLEAENPELCLPDSPTQRVGGVALAKFNQITHLKPMLSLDNVFSEDEFDAFYKRISDKTSETPTFCCEPKLDGLAVSILYRDGVYERAATRGDGSVGEDITENVRTIRSIPLKLRGSDFPPLLEVRGEVIMPKKAFDSLNDRARAKGEKLFVNPRNAAAGSLRQLDSKITASRALGFYAYALGVVEPESWPLGKGHHEQLMQLKSWGFPVSSEVKLCGDVKTVLDYYADILERREALDYEIDGVVIKVDSIEHQLQLGFVAKAPRWATAFKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIARLGVKVGDTVIVRRAGDVIPQVVAIVAEKRPVSANDILFPQTCPVCDSMVERTEGEAVARCTGGLFCEAQRKEAIKHFASRKALNVDGMGDKVVEQLIDKELVASPADLFRLTASAMTMLDRMGMKSATKLVAAIEDAKQTTFARFLYGLGIREVGEATAANLANYFKNLDKLKSADADEFIKVDDVGAIVAQHLTYFFAQPHNLEVVDNLVQAGVHWPEIEEVAEEALSLKGQTWVLTGTLTKLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGEAAGSKLTKAQDLGVKVLDEDGLLAVLAGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SSRP_FLAJ1
Sequence: MLKSVNILNKRARFDYEIIDTYTAGIVLAGTEIKSIRLGKANITESFCEFSGIELFAINTYIEEYSFGNQFNHKSRSERKLLLNKKELKSLHKSVQAKGLTIVPLKLFTNEKGLAKLQIGLCKGKKNYDKRESLKEQDTKRDLDRIKKAYN
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GP16_NPVAC
Sequence: MNFWATFSICLVGYLVYAGHLNNELQEIKSILVVMYESMEKHFSNVVDEIDSLKTDTFMMLSNLQNNTIRTWDAVVKNGKKISNLDEKINVLLTKNGVVNNVLNVQ
What is the function of this protein?
May be involved in formation or transport of the nucleocapsid-containing vesicles around the nuclear membrane.
What are the official names of this protein?
Glycoprotein GP16.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Localizes predominantly close around the host nuclear membrane.