PharMolix/UniProtQA huggingface dataset:
Protein: PSAA_POPTR
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLVAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYAMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGATAPGATASTSLTWGGDDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PH_STAA8
Sequence: MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMIATGERLQGLYAYNIPFDNKARIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDDPMYFIRLNFPDKVSVGDKAKSVIKQATAKKQAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLYWVKSHGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNQKNPPVPAGYTLDKNNVPYKKETGYYTVANVKGNNVRDGYSTNSRITGVLPNNATIKYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGKFSTI
What is the function of this protein?
Has weak lytic activity toward S. aureus cells.  Full-length protein has no activity, but fusion of the Peptidase C51 domain to the lysostaphin SH3 cell wall binding domain yields an active chimeric enzyme, suggesting that PH may be functional.
What are the official names of this protein?
Probable autolysin PH.
Protein: LACG_CLOAB
Sequence: MNNFGEDFIFGGATAAYQAEGATKEDGKGPCIWDEYLKKEGRFTGDTASDFYHKYKEDLKFSRKFGVNGIRISIAWSRVIPDGKGEVNPKGLKFYSDLIDECIKNNVEPFVTLHHFDTPLTLFKDGDWLNRNNIDYFVRFAKVCFEALGDRVKKWITFNEAWAVAQNGYIIGNFPPSIKYDIPKAAQSMHNMMVAHAKVVELYKSMNLDGEIGIVHTLEGKYPITDSKEDKEAAYLDYMISNKFMLDACFKGEYPKETEKTINEIMSKNGGELKIYDGDLEVLKKASSKIDFLGMNYYSSHFLKAYEGESRIHHNGTGEKGTSIFALKGIGERVNNPEVPTTDWDWPIYPKGLHDMLVRIKNEYPNYKKIYVTENGMGYKDDFKDGKIDDTPRIDYINKHLEAILKAKNEGVVVKGYFVWSLMDVLSWSNGYNKRYGLFYVDFKTQNRYAKKSAYWFKRISYEKKLIDFSDIEY
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: DUT_CORGL
Sequence: MTDLAAIKIVRLDKELPLPKRAHRGDAGVDLHATTDAVIAPGHREIVGTGIAIALPLGTVGLVHPRSGLAAREGLSIVNAPGTIDADYRGEIKVCLINLDPEKPIMITRGDRIAQLVIQKVELVDFEEVEELDDTVRGDQGYGSTGKTA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PAND_NOCFA
Sequence: MLRTMMKSKIHRATVTHADLHYVGSVTVDQDLLDAADLLEGEQVCIVDIDNGARLETYVIAGERGSGVIGINGAAAHLVHPGDLVILIAYGMMNEQEIAEYDPKVVFVDERNRPVELGSDPAHAPEGSGLTSPRSLTFA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_PROMH
Sequence: MNVIKGVVAAPNARVAIAIARFNNFINDSLLEGAVDALERIGQVSSENITVVWVPGAYELPLTVKALVESDKYDAVIALGTVIRGGTAHFEYVAGECSSGLSHVAMQSEIPVTFGVLTTESIEQAIERAGTKAGNKGAEAAMTALEMINVLKAIKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: UVRC_LACAC
Sequence: MATELIENKLKLLPEKPGCYLMKDINGTVIYVGKSKNLKNRVRSYFKSKQVGRRAELVREIRDYDIITVSTDKEAFLLEITLIKKYQPYYNVQLKQGTGYPYIEITREHDPQTRLTSVVHKDGGYYFGPYPNVYAAQATLKFIRKVYPLRRCHGYQGRPCLYYHMGQCLGACFKKVPQKEYDEQIKKIKSFLNGDITSVKQDLTTKMEKASENLEFERAAEIRDQLKYIEETVEKQKIISNDNTQRDIFNYYVDKSWISIQIFFLRQAKLLRRETRMFPLTDAADPEDAFTSFIVQFYGQKNRILPKEILIPSGFDDDTLAEVLNVAVRTPQRGQKKSLLDMAKDNAKLKLDDKFRLLELGNRKTKGAQKEIFDALGLPYGHVIESFDHSHIQGADPVSALVVFKDGEPDKTSYRKYKLKGEVEHQNGGDEVRNTREVVRRRYGRLLREHKKMPDLILMDGGQIQVDACEDVLRNELNLNIPVAGMVKDDKHRTNHLLFGDPINGIPLKLIPLDPKSEGFYLMTRIQDEVHRFAITFHRRRHAKNALSSRLDSIKGIGPKSRNKLLRNFGSLKKIKEASIEDLRAAGLTLPQAQTVKLML
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN_HHV2
Sequence: MAAAATPGAKRPADPARDPDSPPKRPRPNSLDLATVFGPRPAPPRPTSPGAPGSHWPQSPPRGQPDGGAPGEKARPASPALSEASSGPPTPDIPLSPGGAHAIDPDCSPGPPDPDPMWSASAIPNALPPHILAETFERHLRGLLRGVRSPLAIGPLWARLDYLCSLVVSLEAAGMVDRGLGRHLWRLTRRAPPSAAEAVAPRPLMGFYEAATQNQADCQLWALLRRGLTTASTLRWGAQGPCFSSQWLTHNASLRLDAQSSAVMFGRVNEPTARNLLFRYCVGRADAGVNDDADAGRFVFHQPGDLAEENVHACGVLMDGHTGMVGASLDILVCPRDPHGYLAPAPQTPLAFYEVKCRAKYAFDPADPGAPAASAYEDLMARRSPEAFRAFIRSIPNPGVRYFAPGRVPGPEEALVTQDRDWLDSRAAGEKRRCSAPDRALVELNSGVVSEVLLFGVPDLERRTISPVAWSSGELVRREPIFANPRHPNFKQILVQGYVLDSHFPDCPLQPHLVTFLGRHRAGAEEGVTFRLEDGRGAPAGRGGAPGPAKASILPDQAVPIALIITPVRVEPGIYRDIRRNSRLAFDDTLAKLWASRSPGRGPAAADTTSSPPTAGRSSR
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: PCXA_BURCE
Sequence: MTTLKQTPSQTVGPYFAYGLCPQQYGYDLKSLFTPTIAAPHADGEHVLLVGQVFDGDGNVVSDAMLEFTQVDGAGRFPASRDDVAKSGFTGFARVGTGTDAQHRFVVETVKPGRIAADEAPHINVTVMMRGILTHAFTRVYFDDEAAANAADPVLNLVPAERRATLVAKRDAQPGRPVVYRFDVRMQGPDETVFFDV
What is the function of this protein?
Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway.
What are the official names of this protein?
Protocatechuate 3,4-dioxygenase alpha chain, 3,4-PCD.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: EHF_BOVIN
Sequence: MILEGSGVMNLNPSNNLLHQQPTWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDVNGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTDPSIMNTWKEENYLYDTNYGSTVDLLDSKTFCRAQISMTTTGHLPIAESPDTKKEQDHPTKPHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
What is the function of this protein?
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation.  May act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades.  Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.  Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter (By similarity).
What are the official names of this protein?
ETS homologous factor, ETS domain-containing transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSB_YERPP
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDFVRVKEDVAAQEANNSTLKARNDQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPDQSRRNAGTPSTQNNAQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: HSLO_LISMO
Sequence: MSDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADSNAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQINSSVGVGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLMALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECNCSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNTYDFSEEELKTLYEEAK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_CAUSK
Sequence: MPDWLIAIVLGLVEGLTEFIPVSSTGHLLLTKIALGLTDPAWDTFIVLIQLGAVLGVVALYFQRLWAVVVGLPTQPEARRFALTVLIGCIPAFAAGLALHGVIKHFFENPYLPQVICVSLILGGVILLVVDKKAPPPREMDGMALSLKTAALIGLFQCLSLLPGVSRSGSTIVGSMLIGVDRKAAAEFSFFMAIPIMVGAFALDLLKSYKDIDASHAGAIAIGFVVSFLSGLVVVKFLIDFVGKRGFTPFAWWRIVVGVIGLGLIYIPR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: USPB_VIBC1
Sequence: MISGDTILFALMVVTGVNMVRYLTALRSLIHIMREAHPLLYQQVDGNGFFTTHGNVTKQVRLYHYIKSKEYHHHHDEIFTGKCERVRGLFILSTALLGVTLLAAFIL
What are the official names of this protein?
Universal stress protein B homolog.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX2_MAXSU
Sequence: MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISTLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPALTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: QUEC_NAUPA
Sequence: MKKAVVILSGGMDSTTAAFIAKSEGYEIIPVHFNYSQRTEKRELKAFNDICDYLNLDNRYIIDIPFFKQIGASALVDENIDVPVDGVKPGIPVTYVPFRNGIFLSIAAAVAEKEGAEAIYIGVVEEDSSGYPDCTEDFIQNMQKAVNSGTKPETNIEIKTPLVHLKKEDIVKTAVKYNVPLHLTWSCYKNEDEACGVCDSCRLRLKGFEKAGIEDRIPYKQK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DAPE_METPB
Sequence: MSDQSPLALAHALIRCPSVTPEEGGALSFLAERLTEAGFSVERPVFSEAGTPDIENLYARIGTAGPVLVFAGHTDVVPPGEAASWTHGPFSGEITDGFLYGRGAVDMKGGIACMLAATLSFLDRHGPDFGGSIAFLITGDEEGPAVNGTVKLLDWAKARGERFDHCLLGEPTNPDSLGEMIKIGRRGSLTGRITVHGRQGHVAYPHRAENPIPGLLRLASALIAEPLDGGTAHFDASNLEFTTIDVGNPATNVIPASAKAVFNVRFNDDWTAETLGAEIRKRLEAAAGNAVRFSLDLQPSNSPAFLTQPDAFVDLVADAIAAETGRRPALSTTGGTSDARFIKDACPVIEFGLVGRTMHETDERVAVADLDRLTAIYGRVLERYFSS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PSAC_PIPCE
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RECX_SALAR
Sequence: MSEPTPRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATPDDYERVISWCHEHHYLDDNRFVIRFIASRSRKGYGPARIRQELNQKGIARESTEKAMRECDIDWSEMAREQAVRKYGEPLPSTFSEKVKVQRFLLYRGYLMDDIQEIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_HELPJ
Sequence: MKVFDYEDVQLIPNKCIVNSRSECDTTVILGKHAFKMPIVPANMQTIINESIAEFLAENGYFYIMHRFNGSARIPFVKKMKERQLISSISVGVKKEECLFVEELAKQGLTPDYITIDIAHGHSNSVIEMIQRIKTRLPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGATMVMIGSLFAGHEESSGETKIENGIAYKEYFGSASEFQKGEKKNIEGKKIWIQHKGSLKNTLIEMHQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: PUR9_HYDCU
Sequence: MKPVRRALISVSDKNGILEFAKSLTAMDVVILSTGGTYKVLSEAGLPVTEVSEYTGFPEMMDGRVKTLHPKIHGGLLGRRGTDDAVMAEHGIDPIDMVVVNLYPFEATVAKPDCSLEDAIENIDIGGPTMLRSAAKNHKDVAVVTDPHDYARILEEMESNDGQLSHATRFDLAIKTFEQTARYDGAISNYFGTMFSDDKDDTFPRTYNTQFVKKQSMRYGENPHQSAAFYTERNPTEASISTAKQLQGKALSFNNIADTDAALELVKTFEETACVIVKHANPCGVSIGENVFESYDRAYKTDPTSAFGGIIAFNRALDQETAQAIIDRQFVEVIIAPNVSEDAKNVIAAKQNVRLLVCGDLGIQEPAYDYKRVTGGLLVQDRDLGSVTEDELKVVTKRAPSEKEMADLQFAWKVAKYVKSNAIVYVKDGMTIGVGAGQMSRVYSAKIAGIKAADEGLEVPGSVMASDAFFPFRDGIDAAAEAGITAVIHPGGSMRDQEVIDAADEHGIAMVFTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GFA_XANCB
Sequence: MANVSIHPAVDGGVVHGSTEGFAGGTLQCLCASDKVTVDVASQSAHNHACGCSKCWKPEGAKFSVVAVAPRDKVTVTAHPEKLKIVDESATIQRHACTGCGVHLYGRIENKDHAFYGLDFIHTELSQQSGWSPPGFAAFVSSIIETGTPPDQMDGVRARLTELGLTPYDCLSPALMDALSTNVARHKGLLH
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CH603_RHIEC
Sequence: MSAKEIKFSTDARAHLLRGVELLNNAVKVTLGPKGRNVVIDKAYGAPRITKDGVTVAREIELGNKFENMGAQMVREVASKTNDLAGDGTTTATVLAASIFREGAKLVAAGMNPMDLRRGIDLGVSAIVKEIQARARKVKSSGEIAQVGAIAANGDATVGEMIAKAMEKVGNEGVITVEEARTAETELDVVEGMQFDRGYLSPYFVTNAEKMRVELEDPYILLHEKKLGSLQALLPILEAVVQTGKPLLLISEDVEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAALTSGQMISEDLGIKLENVTLYMLGRAKRVLIEKDTTTIIDGTGEKAAIQARIQQMKAQIEETTSDYDKEKLQERLAKLAGGVAVIRVGGATETEVKEKKDRIEDALNATRAAVEEGIVPGGGVALLRAKSALTGMVGENADVTAGISIVLRALEAPIRQIAENAGFEGSIIVGRLTGRNDHNQGFDAQTETYVDMVEAGIVDPAKVVRTALQDAGSIAALLITAEVMIADIPARNPAPAVGNGGMGDMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_FUSNN
Sequence: MNIKPIGERVLLKPIKKEEKTKSGILLSSKSSNTDTQNQAEVIALGKGEKLEGIKVGDKVIFNKFSGNEIEDGDVKYLIVNAEDILAIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_SULIY
Sequence: MKIGIIAYQGSFEEHYLQLKRAFDKWSINGEITPVKIPKDLKDIDGVIIPGGESTTIGLVAKRLGILDELKEKITSGLPVMGTCAGAIMLAKEVSDAKVGKTSQPLIGAMNISIIRNYYGRQRESFEAIIDLSKIGKGKANVVFIRAPAITKLWGKAQSLAELNGVTVLAEENNILATTFHPELSDTTSIHEYFLHLVKG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DNHB_NOCS1
Sequence: MTGRQRTTVVAPDRPVQDATISQLTTRVWTVAIDGYRTIVVEGETGIVAINSFGTPSAQTKYRELITQTFGDKPVVAVVASIDHLDHTGRLGPFANGAEVIGHELGQAIAFGRGLPEQKLADTVVTGPVTEIERAGVRLVLRYPAPTVGTGNLAVDLPDDDVVFMVGLQSGARYGIFPDFHFKHFLRATSEIAALGRRYFVPGRSEVMDAGQVRQALEYVNDFQNACQRCLAGGEVPHWLLEPTTAYLHDELSSKWSHLEGYDPVAVGLGGLRVVCHYYMGGWWLDDTDHHELLYDHLTVRTYREYRERLATAGTGRA
What is the function of this protein?
Involved in the degradation of 2,4-dinitroanisole (DNAN), an insensitive munition ingredient used in explosive formulations as a replacement for 2,4,6-trinitrotoluene (TNT).  Catalyzes the removal of the methyl group from 2,4-dinitroanisole (DNAN) to yield 2,4-dinitrophenol (2,4-DNP) and methanol.
What are the official names of this protein?
2,4-dinitroanisole O-demethylase subunit beta, DNAN hydrolase subunit beta, DNHB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: HFLD_PSEP1
Sequence: MSNLQEQLIALGGVFQAAVLVDRIARTGQASEANIGCMLGSLLVRDPKDTLEVFGGDDLNLRDGYRALIGALERDPNSLQREPLRYALSMLGLERQLNKRGDLLDTIGNRLPQIQSQAEHFGLVHENVIASSGALYQDTLSTLRQRIQVHGDMRFLQQPNNASKIRALLLAGIRAARLWRQLGGHRWQLVFSRRKLLNELYDMMRSPN
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PLSY2_LACJO
Sequence: MSTLNYLLIFILAYLIGSFPTGVLVGKIFFHEDIRNFGSGNIGTTNSFRVMGPVAGSAVLVIDVLKGTLATDLPLIFHLKGPKYLLLIAGACAILGHTFSIFLKFKGGKAVATSAGVFLGYNLKFFGLCALVFLPMLFITSYVSLSSLVSIVIIFICSFWFHDIFLTIITGIMMILLFVRHRSNIKRLINHEENIVPFGLWYWYKKSHGLLKKNAKNK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 2, Acyl-PO4 G3P acyltransferase 2, Acyl-phosphate--glycerol-3-phosphate acyltransferase 2, G3P acyltransferase 2, GPAT 2, Lysophosphatidic acid synthase 2, LPA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.