PharMolix/UniProtQA huggingface dataset:
Protein: RS19_BORT9
Sequence: MARSIKKGPFIEKSLYQKVLASSGREKRVVIKTYSRASTIIPEMVSLTISVYNGKSFIPVYITEDLVGHKLGEFSPTRIFRGHAKSDKKGRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y2994_RUMCH
Sequence: MQILVDADACPVKDIITKNAKKYGIPVIMIIDTSHELNDGYSTVITVDKARDSVDIKLINMVQRGDIVVTQDYGVAAMGLGKGAKVLNQNGLIYSDANIDRLLFERHLGQKIRRAGGRTGTIRKRSKENDEAFEKALLLFIKPESEGPRDLKI
What are the official names of this protein?
UPF0178 protein Ccel_2994.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RHCG_GASAC
Sequence: MGNCADCLRGFFCPPKNTNIRISLPAVCFVWQIAMIVLFGVFIRYDAESDIRLWLQLKHTNNITSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGGVGFNFLIGAFGLQWALLMQGWFHALDPTTGKISIGVEGLINADFCVAASLIAYGALLGKVSPVQLMVVTLFGVTLFAVEEYIILNLLHCRDAGGSMVIHCFGGYYGLTISWILYRPKLHQSKRLNGSVYHSDVFAMIGTLFLWMFWPSFNSAITDHGSGQHRTAINTYIALASSVLTTVAISSASEKRGKLDMVHIQNATLAGGVAMGTAAEFMITPYGALIVGFCTGIISTFGYLFVSPFMEKYLKIQDTCGVHNLHAMPGMLGGFIGAIVAAAATEEVYSREGLIETFDFEGKFADRTVGTQGGFQAAGVCVAIAFAVVGGAVVGLILRLPIWGDPADDNCFDDEVYWEVPEDEEGILPVLEYNNHMTHKHQDISESNFSVEQS
What is the function of this protein?
Functions as an ammonia transporter.  May play a role in the elimination of ammonia in the gill (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type C, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: PBP2_NEIMA
Sequence: MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSDRNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFVFEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKALDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGETAGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEPGGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGSLNILGISPTKPLTAAAVKTPS
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
What are the official names of this protein?
Probable peptidoglycan D,D-transpeptidase PenA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. FtsI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DUT_RHIE6
Sequence: MTIHHETRPTLNLIRLANGEGLELPAYESQGAAGMDLRAAVDGDAPLTLPPGKRALVPTGFIFEIPEGFEGQVRPRSGLAFKHGITCLNSPGTVDSDYRGEVKVLLANLGEEAFVIERGMRIAQMVIAPVTQARVAEITAASETARGAGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: KDTA_HAEIN
Sequence: MWRFFYTSLLLICQPLILCFIGLLSVKSPRYRQRLAERYGFYGNASCPPPQGIFIHAASVGEVIAATPLVRQLQQDYPHLSITFTTFTPTGSERVKATFGDSVFHYYLPLDLPFSIHRFINFVQPKLCIVMETELWPNLIHQLFLRNIPFVIANARLSARSAHRYGKIKAHLQTMWSQISLIAAQDNISGKRYATLGYPKEKLNITGNIKYDLNTNDELLRKIDSLRTLWKQDRPIWIAASTHNGEDEIILKSHRALLAKYPNLLLLLVPRHPERFNVVADLLKKEKFQFIRRSTNELPNENTQVILGDSMGELMLMYGISDIAFVGGSLVKHGGHNPLEPLAFKMPVITGKHTFNFPEIFRMLVEVQGVLEVNSTADALERAVEALLNSKESRERLGNAGYEVLMENRGALQRLLDLLKPYLERNV
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of a single 3-deoxy-D-manno-octulosonate (Kdo) residue from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.  Is strictly monofunctional, i. e.  is capable of adding only a single Kdo residue to the acceptor lipid.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Monofunctional Kdo transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: RNPH_CUPMC
Sequence: MRPSGRAADALRPITLTRQYTRHAEGSVLSAFGDTKVLCTASVLAKVPPHKKGSGEGWVTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRAMRSVFDLAALGEYTIHLDCDVLQADGGTRTAAITGAFVAAHDAVSAMLRDGQIKASPIRDFVAAVSVGMVNGVPVLDLDYAEDSNCDTDMNVVMTGSGGFVEVQGTAEGTPFSRADLDAMTRLAEAGIAELVRHQKQALGL
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: AJL1_ANGJA
Sequence: MDFVEVKNLIMKSGMELKVNGVFNANPERFSINVGHSTEEIAVHVDVRFSYLSDKRQLIINHKTGDAWQEEQRDARFPFTAGQAFQVSVVFNFDTFDIYLPDGQVAHFTNHLGAQEYKYIFFVGDATVKNISVNVADKPTKR
What is the function of this protein?
Involved in host defense at the body surface.  Causes agglutination of the Gram-positive bacterium S. difficile.  Possesses calcium-independent hemagglutinating activity.
What are the official names of this protein?
Galactose-binding lectin l-1, Galectin, Ajl-1.
What are the subcellular locations of this protein?
Secreted.
Protein: FLOA_BACP2
Sequence: MDPSTLLLFVIIAAGLIVLSIFFTFVPVMLWISALAAGVRVSIFTLVGMRLRRVIPNRVVNPLIKAHKAGLDVTINQLESHYLAGGNVDRVVNALIAAQRANIELNFARCAAIDLAGRDVLEAVQMSVNPKVIETPFISGVAMDGIEVKAKARITVRANIERLVGGAGEETIIARVGEGIVSTIGSSNNHKRVLENPDMISQTVLGKGLDSGTAFEILSIDIADVDIGKNIGAILQTDQAEADKNIAQAKAEERRAMAVAQEQEMRAKVEEMRAKVVEAEAEVPLAMAEALREGNIGVMDYMNIKNIDADTDMRDSFGKMTKGPSDNENK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: GLPK_BORAP
Sequence: MKYILSIDQGTTSSRAIVFDKNANIKGIAQKEFTQIYPQPSWVEHDPTEIWGSQLGVITEALANSRILPNEVDAIGITNQRETTVIWEKNTGKPIYNAIVWQDRRTAKICDQLTKEGKDKIILEKTGLVLDSYFSGTKILWILDNVEGARQKAENGELCFGTIDTWLLWNLTQKKVHATDYSNASRTLLLNIKTLEWDDELLNILNIPKAILPELKESSTIYGKTDKSLFGAEIPIAGIAGDQFAATFGQACLKKGMAKNTYGTGCFLTVNIGKEPIINHERLLTSIAWGRKKSVTYVLEGSVFIGGAVIQWLRDGLEFFRKSSDAESLASSASDNGGVYFVPAFVGLGAPHWDSYARGTIIGITRGSTKAHITRAALESIAFQSFDILNTMKKSIPNFEIKELRVDGGASQNNLLMQFQADLLECKVVRPKITETTALGAAYLAGLASGYWQSAEEIVSLWQVDKIFEPSMPKNQKEKLLENWNRAIERSKSWIQNSHSL
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SWI3_YEAST
Sequence: MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMNDHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPSVQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDANLLEEGETSRPLKKVKILEQIDENWSKEDLQKLLKGIQEFGADWYKVAKNVGNKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLGPLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQSMTQRAIQSAESIKSQKEEISDQKPIEHIKEGSEIAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAEKEEIRSQIDHFKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA
What is the function of this protein?
Involved in transcriptional activation.  Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
SWI/SNF complex subunit SWI3, Transcription factor TYE2, Transcription regulatory protein SWI3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_CANLF
Sequence: MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
Ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: HOT_PONAB
Sequence: MAAASRARVAYLLRQLQRAACQCPTHSHTYSQAPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDASFMEAIEFAQKGAFDAYVAVGGGSTMDTCMAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKIGIASRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHLRSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRNPDDLEARSHMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGADTRTARIQDAGLVLADTLRKFLFDLDVDDGLAAVGYSKADIPALVKGTLPQERVTKLAPRPQSEEDLAALFEASMKLY
What is the function of this protein?
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).  L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).
What are the official names of this protein?
Hydroxyacid-oxoacid transhydrogenase, mitochondrial, HOT, Alcohol dehydrogenase iron-containing protein 1, ADHFe1.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACDH_NOVAR
Sequence: MAKMKCAIIGSGNIGTDLMIKLLKGSDTLELAAVVGIDPASEGLAMASERGVPTTHEGIEGLCRMPQYADIGIAFDATSAYAHKAHDEILARDGKLMVDLTPAAIGPATIPPVNPAVDAAVRNINMVTCGGQATIPIVAAVSQVAKVHYAEIVASVSSRSAGPGTRANIDEFTRTTARAIETVGGAAKGRAVIILNPAEPPMIMRDTIFTLSEMVDEDKVRDSVLAMIARVQSYVPGYRLKQEVQFERFGSNRPLKIPGYGEFEGLKTSVFLEVEGAGDYLPNYSGNLDIMTAAAKAAGESLAKTHMEKTAA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: IOVO_ANSAN
Sequence: VATVDCSDYPKPACTVEYMPLCGSDNKTYDNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: HLDE_YERPB
Sequence: MKVTLPDFRRAGVLVVGDVMLDRYWYGPTSRISPEAPVPVVKVDTIEERPGGAANVAMNIASLGAVARLVGLTGIDDAARALICKLSEVRVRCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFDGVDPTPIFERIQLALPQIGALVLSDYAKGALNSVQPMIQLARKANVPVLIDPKGSDFERYRGATLLTPNLSEFEAVVGRCKNEEELVNRGMQLVADFELSALLVTRSEQGMTLLQLGKPPLHLPTQAKEVFDVTGAGDTVIGVLAAALAAGNSLEESCFLANAAAGVVVGKLGTSTVSPIELENAIRGRAETGFGVMDEQQLKIAVAQARQRGEKVVMTNGIFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGEKRPVNPLEQRMVVLGALEAVDWVVPFEEDTPQRLIADILPDLLVKGGDYKPHEIAGSEEVWAAGGEVKVLNFEDGVSTTNIIQSIKNGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: MNME_MAGMM
Sequence: MLRTPLLHEQDCIIGMATPPGTSGVAVLRLSGPGVLSLVVPYLYTPKGEKVAESGFKPRVMRRLNFIDPQAPDVPLDHMLVVHFPNPHSFSGEDMVELHGHGAPVVVKRIMEVLVAHGVRPADPGEFSKRAFFNNKMDLVQAEALMGLIEATSLRAAREASRQMTGTLSEHLMALKDHLVLTYAHLEAALDFSDEDIEPESEGGLLDRLAYVHAGIKKMLGTAELGRQMRDGFELAIVGRPNVGKSSLFNALSGEDRAIVTDLAGTTRDLNESNLEIHGLPILLVDTAGLRESDDPVERIGIERAWQRVERADGIVFVAEAQLGVTLEDKALLQRLPKEKALWVWNKLDQLEGALPECLQDWPEEQICGVSCHTGEGLESVVAHIVARMEQLPEHGEGVVIMQLRQQQTLQQAIVLIEEAQEMLANGQWLELVAEPLTRSIDQLTQLMGNTDYEDVLGMVFSSFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_BREBN
Sequence: MGLPVVAIVGRPNVGKSTIFNRLIGERVAIVEDMPGVTRDRLYGKGEWLTHTFHVIDTGGIEFGETDEILTQMRYQAELAIDEADVIIMIADSRTGVTDADVELSRMLNRTGKPVVLAVNKADNPEMRADIYDFYSLGLGEPFPVSGSHGLGLGDMLEEVCQHFPAEDDEEKRDDVIRVSIIGRPNVGKSSLTNAILGEERVIVSEVAGTTRDAIDTPFERDDQSYVLVDTAGMRKRGKVYETTEKYSVMRAMRSIEDSDVVLVVINGEEGIIEQDKKIAGYAHEAGRGVIIIVNKWDAIEKDDKTMQRFTELIREEFKYLDYAPILYVSAKSKQRVHTILPKVNEVAQAHSMRIPTAVLNDLVTDATIRTPPPSDRGKRLKINYATQATVKPPTFILFVNDPELMHFSYERYIENKIREAFVFEGTPVRIWTRKKT
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NU1M_BALMU
Sequence: MFMINILTLILPILLAVAFLTLVERKILGYMQFRKGPNIVGPHGLLQPFADAIKLFTKEPLRPATSSTTMFIIAPVLALALALTMWSPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSYTLSTLATTQEQLWLLFPSWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNMFTAILFLGTFHNPCNPELYTTNLIIKTLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHISLPIMTASIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SERB_ARCFU
Sequence: MFVMFIVAEVDDEVCVKREVERAAGEVGVHVSLTPFQRREKAEKNLYVVTILGKDRVGIVRDITRAFLDFGINIERTSLTAREELISIEFLVDLGQRDAAEVRKRLRREAERLGLDIVMQPYSTFNREKRLIVFDMDSTLVEAEIIDELAKEAGVGDEVSKLTERAMRGEIGFKEALEERVRLLKGLPVEVLERIYSRIKLTEGAKELVRSLKEAGYKVAVVSGGFSYFTDRLKEELGLDYAFGNELEIENGRLTGRIKGRIIDASEKARIVEEIARKEGISPENVVAVGDGANDRLMIERAGLGIAFNAKEVLKDVADGSISKENLVGLASVLKLPAEFRKKV
What are the official names of this protein?
Phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: PDIA4_BOVIN
Sequence: MRPRKAWMLVLLLALVQLLAVASAGAPDEDSTDKEDAIEEDEEEDEDDDDDDDDLEVKEENGVLILNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIAATLKENDPPIPVAKIDATSESALASRFDVSGYPTIKILKKGQEVDYEGSRTQEEIVAKVKEVSQPNWTPPPEVTLVLTKDNFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKSSPPIPLAKVDAIAETDLAKRFDVSSYPTLKIFRKGKAFSYNGPREKYGIVDYMMEQSGPPSKQILALKQVQEFLKDGDDVIIIGVFKSESDPAYQLYQDAANSLREDYKFHHTFSTEIAKFLKVSLGKLVVMQPEKFQSKYEPKSYVMDIKDSTEAAAITEHVVKHTLPLVGHRKAADAKRYTRRPLVVVYYSVDFSFDYRAATQFWRNKVLEVAKDFPEYTFAVADEEDFATELKDLGLSESGEEVNAAILDEGGRRFAMEPDDFDADALRDFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGHKNLVIAKMDATANDVTSDRYKVEGFPTIYFAPSGDKKKPIKFEDGNRDLEHLSKFIEEHATKLSRTKEEL
What are the official names of this protein?
Protein disulfide-isomerase A4.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Melanosome.
Protein: SFSA_GEOSM
Sequence: MKLPQPLFQGTLIRRYQRFLADVELEDGTVVTAHTPNTGSMMGCACPGNRVLLSKSASLTRKYPHSWELVQADGTWVGINTQLPNLLAREAILDGTISELSGYRQIRGEVPYGSGSRIDLLLSGERGLCYVETKNVTLVKDGVALFPDAVSARGQKHLRELMEMVRQGHRAVNLFIVQRADGVALAPADAIDPVYGRLLREAAQNGVEILAYRAEVTRTEVRLERALPVLL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: CLPX_SHIBS
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKGVIDESVIDGQSKPLLIYGKPEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: EFTS_EDWI9
Sequence: MAEITASLVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILTKVAADGKYGVIVEMNCETDFVAKDAGFKAFADEVAAAALADKIINIDTLKAKFEEQRTQLVAKIGENINIRRVSELTGDLLGTYSHGARIGVMVAATGADEELIKHIAMHIAASKPEYVKPEDVPADVVAHEHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEVSLTGQSFVMDPSKTVGQLLKEHNANVTGFIRFEVGEGIEKVETDFAAEVAAMSKGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX5_RAT
Sequence: MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQEACGPRTPAAQHSTMEVDGNKVMSSLAPYNSSTSPQKAEEGGRQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGISNCRTEKEKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYEEYEEEEEDPDVDYGSDSENHIAGQAN
What is the function of this protein?
Transcription factor involved in chondrocytes differentiation and cartilage formation (By similarity).  Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes, such as COL2A1 and AGC1 (By similarity).  Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate (PubMed:26150426).  Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (By similarity).  Together with SOX6, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (By similarity).  Binds to the proximal promoter region of the myelin protein MPZ gene (By similarity).
What are the official names of this protein?
Transcription factor SOX-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_NOCFA
Sequence: MAEHPDLPPLRIADREFGSRLIMGTGGAENLAVLEEALVASGTELTTVAMRRVDAAGGTGVLDLLKRLEITPLPNTAGCRTAAEAVLTAQLAAEALDTTWVKLEVVADERTLLPDPIELLSAAEQLVDAGFTVLPYTNDDPVLARRLEDAGCAAVMPLGAPIGTGLGIGNPHNIEMIVAAAGVPVILDAGIGTASDAALAMELGCSAVLLATAVTRAKRPPLMAAAMADAVRAGLLAREAGRIPKRFWAQASSPQR
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BRUA2
Sequence: MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTGGKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIADAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVLLHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLRQLARIIDLSRAEEAGTAQAEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.