PharMolix/UniProtQA huggingface dataset:
Protein: ANDR_RAT
Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREAIQNPGPRHPEAASIAPPGACLQQRQETSPRRRRRQQHPEDGSPQAHIRGTTGYLALEEEQQPSQQQSASEGHPESGCLPEPGAATAPGKGLPQQPPAPPDQDDSAAPSTLSLLGPTFPGLSSCSADIKDILSEAGTMQLLQQQQQQQQQQQQQQQQQQQQQQEVISEGSSSVRAREATGAPSSSKDSYLGGNSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYASLLGGPPAVRPTPCAPLAECKGLSLDEGPGKGTEETAEYSSFKGGYAKGLEGESLGCSGSSEAGSSGTLEIPSSLSLYKSGAVDEAAAYQNRDYYNFPLALSGPPHPPPPTHPHARIKLENPSDYGSAWAAAAAQCRYGDLASLHGGSVAGPSTGSPPATASSSWHTLFTAEEGQLYGPGGGGGSSSPSDAGPVAPYGYTRPPQGLASQEGDFSASEVWYPGGVVNRVPYPSPSCVKSEMGPWMENYSGPYGDMRLDSTRDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGENSSAGSPTEDPSQKMTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
What is the function of this protein?
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation.  Transcription activation is also down-regulated by NR0B2.  Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 (By similarity).
What are the official names of this protein?
Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Protein: IF1C_NUPAD
Sequence: MKEQKLIHEGLITESLPNGMFWVRLDNEDLVLGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLGA_SALHS
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDVRVLLPGFPDIRRGIPDAHVVSRRDTFAGKISLLFGHYNGVGIYLIDAPHLYERPGSPYHDTNLYAYTDNVLRFALLGWVGCEMACGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAKHMDDIELPWSFFNMHGLEFNGQLSFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLRQRHLEGRLSGILNGVDEKIWNPESDLLLASRYTRDTLEEKAENKRQLQIAMGLKVNDKVPLFAVVSRLTNQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEHPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDSSLENLADGIASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RPIA_STRMK
Sequence: MSEAKRLAAEKAIEYVEDGMIVGVGTGSTVAYFIDALARIQHRIKGAVSSSEQSTARLKQHGIEVIELNHSGNLSLYVDGADECDANKCLIKGGGAALTREKIIAEASERFICIIDPSKQVPVLGRFPLPVEVIPMARSLVARQIRDMTGGQPTWREGVVTDNGNQILDIHNLQITDPEKLERELNQLPGVVCVGLFARRRADVVIVGGEPPVVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GLYC_OLVVA
Sequence: MGQVIGFFQSLPNIINEALNIALICVALIAILKGIVNIWKSGLIQLFIFLILAGRSCSHTFQIGRNHEFQSITLNFTQFLGYAPSSCSVNNTHHYFRGPGNVSWGIELTLTNNSVINASNSLKVFTNIHHNITNCVQNIDEQDHLMKWLIETMHLQIMKPGKRLPPILCEKDKGLLIEYNLTNIASREEKHSEYWSQLLYGLSKLLGSSKSLWFDYCQRADCMMQEHSSHLKCNYSECSGHTTFKYLILQNTTWENHCEFNHLNTIHLLMSSTGQSFITRRLQAFLTWTLSDATGNDLPGGYCLEQWAIVWAGIKCFGNTAVAKCNQNHDSEFCDMLRLFDYNRNAIKSLNDQSQSRLNLLTNTINSLISDNLLMKNKLAEIMNIPYCNYTKFWYINDTRTGRHTLPQCWLISNGSYLNETKFRTQWLSESNALYTEMLTEDYDKRQGSTPLSLVDLCFWSTLFYVTTLFAHLVGFPTHRHILDGPCPKPHRLTKKGICSCGHFGIPGKPVRWVKRSR
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: SYDND_CHLCV
Sequence: MKYRTHRCNELSLSNVGERVRVSGWVHRYRNHGGVVFIDLRDRFGITQIVCREDEKPELHQLVDSVRSEWVLSVEGTVCRRLEGMENANLATGDIEVEIEKVDILSKAKNLPFSISDDHIHVNEELRLEYRYLDMRRGQILDRLIYRHKVMLACRQYMDKQGFTEVVTPVLGKSTPEGARDYLVPSRIYPGSFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQPEFAQIDIEMSFATPDDLFPIIEQLVVEMFSVQGIKIDLPLPRMTYQEAKDLYGTDKPDLRFGLQLRDCREHAKQFSFSIFLDQLAQGGTIKGFCVPGGADMSRKQLDVYTEFVKRYGAMGLVWIKKQENGLASNVAKFASEEVFDAMFADFSAKDNDILLLIAAPESIANQSLDHLRRLIGKERNLYNESQYNFVWITDFPLFAKEEGKICSEHHPFTSPLDEDISLLDTDPLSVRSSSYDLVLNGYEIASGSQRIHNADLQNKIFSILELSPESIKEKFGFFIDALSFGTPPHLGIALGLDRIMMVLTGAEGIREVIAFPKTQKAADLMMNAPAEIMTSQLKELNIKVTS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_DEHM1
Sequence: MSEKVVLAYSGGLDTSAAVKWLQEKYGMDVIAVTIDVGNEKDFTLIKEKALKVGAKKAYVRDVRKEFAEDYIWKAIKANSMYEGVYPLATALARPLIAKVMVDIAMEEGATAIAHGCTGKGNDQVRFDVGINTLAPHLKIIAPARQWGMTREQTMEYAQKWGIPVPISVKNPFSIDENLWGRSIECGLLEDPWNEPIPEVFAWTRPVEATPDAPEYLEVEFEQGVPVAVNGEKLSPLALIQKVHDIAGLHGVGRIDHVENRLVGIKSREIYEAPAAVVLIAAHQALEAMTLSKSQLRFKQMVEATYSDIIYNGLWFSALRQDLDAFIESSQRFVSGTVRLKLSKGSFRVVGRKSPYSLYHKGMATYDKGDQFDPSSAVGFITLWGLQAKLQAQLQPILEEEKGNKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUB3_ARTOT
Sequence: MGCIKVISVFLAAVAAVDARAFFHNRGGNDVIPNSYIVVMKDGVTAEDFDSHISSVATTHSINKAKRGSETVGHKDSFNINGWRAYNGHFDEATIESILNDDKVDYVEHDRVVKLAALTTQPNAPTWGLGRVSHKAPGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDNTDGNGHGTHTAGTFAGTTYGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDAKAKGALGKAALNLSLGGAFSQANNDAVTRAQNAGIFVAVAAGNDNKDAKNSSPASAPAVCTAASSTIDDQKSSFSNWGTIVDIYAPGSNILSAAPGGGTRTLSGTSMASPHVCGVGAAMLAQGVSVAQACDRIKQIANAVIKNPGTGTTNKLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IROE_ECOL6
Sequence: MYAREYRSTRPHKAIFFHLSCLTLICSAQVYAKPDMRPLGPNIADKGSVFYHFSATSFDSVDGTRHYRVWTAVPNTTAPASGYPILYMLDGNAVMDRLDDELLKQLSEKTPPVIVAVGYQTNLPFDLNSRAYDYTPAAESRKTDLHSGRFSRKSGGSNNFRQLLETRIAPKVEQGLNIDRQRRGLWGHSYGGLFVLDSWLSSSYFRSYYSASPSLGRGYDALLSRVTAVEPLQFCTKHLAIMEGSATQGDNRETHAVGVLSKIHTTLTILKDKGVNAVFWDFPNLGHGPMFNASFRQALLDISGENANYTAGCHELSH
What is the function of this protein?
Catalyzes the hydrolysis of both the apo and Fe3(+)-bound forms of enterobactin (Ent), monoglucosyl-C-Ent (MGE), diglucosyl-C-Ent (DGE) and triglucosyl-C-Ent (TGE).  It prefers apo siderophores as substrates and hydrolyzes the Fe3(+)-bound siderophores very inefficiently.  Tends to hydrolyze the trilactone just once to produce linearized trimers.  May hydrolyze and linearize some or all of apo enterobactins while they are being exported.
What are the official names of this protein?
Apo-salmochelin esterase, Enterobactin hydrolase IroE.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: GERD_BACSU
Sequence: MSKAKTLLMSCFLLLSVTACAPKDQAADMDYDQTKKMVVDILKTDDGKKAIKELLNDDAMNEALVIDQDAIKGTIEKTLTSKKGEEFWKNIFEDTDFAEGFAKTLQTEHEKVIKKLMKDPDYQKMLMSVMQDPGMDKKYSQLAKSQEFRSYLEEVINETLSSPLYKKQFEDELKKAAKDTAKESE
What is the function of this protein?
May be involved in fructose recognition during germination.
What are the official names of this protein?
Spore germination protein GerD.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PELO_SULIK
Sequence: MRILEFDEKRQAAKLHIESEDDLWILHLILEKGDKVVAKTTRDIGLGKESRRIPMTIVLKVDYTEFQEFTNRLRIHGIIEDAPERFGIRGAHHTINLDIGDEIIIIKQQWSKYALDKLKKQADKRSKIIIALVDFDEYLIAIPFEQGIKILSEKSLRSLNEEEGIIEQNALEVATELAEYVKQYNPDAILLAGPGFFKEEVAKKVNNILKNKKVYIDSVSSATRAGLHEILKRDIIDKIMSDYEIAIGAKKMEKAMELLAKQPELVTYGLEQVKNAVEMGAVETVLLIEDLLSSNNQERLAIERILEDIENKRGEIILVPKESPIYFELKNLTGILAILRFRIN
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_PSEPK
Sequence: METVVGLTAIAVALLIGLGALGTAIGFGLLGGKFLEGAARQPEMVPMLQVKMFIVAGLLDAVTMIGVGIALFFTFANPFVGQIAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECF_STRCO
Sequence: MSKLGTLGARLHHGEVGYDFVKNRKIWYGISILITITAIVGLAVRGLHMGIEFQGGAVFTTPKNMSASVAQTETWAEEASGHDAIVQKLGDGSLRIQIAGTDTQQSDQIKEDLSKNLDVSAEKINADLVGPSWGDQIANKAWQGLGIFMVLVVIYLAIAFEWRMALAAFVALIHDITITVGIYALVGFEVTPGTVIGLLTILGYSLYDTVVVFDSLKEQTRDITKQTRWTYAEIANRSINSTLVRSINTTVVALLPVAGLLFIGGGVLGAGMLNDISLSLFVGLAAGAYSSIFIATPLVADLKEAEPQMKALKKRVLAKRAQGAAKGESAESAADEGAYDADEPDDAAPAVVGPRNQPASRGRGRGRPSGKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCK_BACSU
Sequence: MKEHHIPKNSIITVAGTVGVGKSTLTKTLAKRLGFKTSLEEVDHNPYLEKFYHDFERWSFHLQIYFLAERFKEQKTIFEAGGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPYFPHPDVLIYLEGDLENILNRIEQRGREMELQTSRSYWEEMHTRYENWISGFNACPVLKLRIEDYDLLNDENSIENIVDQIASVIHDNQKK
What is the function of this protein?
Plays an essential role in generating the deoxyribonucleotide precursors dATP and dCTP for DNA metabolism.  The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd).  The specificity toward the sugar moiety of the nucleoside is less strict.  Both 2-deoxyribose, ribose, and arabinose nucleosides are phosphorylated, although the 2-deoxyribonucleosides are preferred.  The phosphate donor specificity is dependent on the deoxyribonucleoside substrate, but GTP is efficient with both deoxycytidine and deoxyadenosine.  Only nucleoside triphosphates can act as phosphate donors.
What are the official names of this protein?
Deoxyadenosine/deoxycytidine kinase, dAK/dCK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
Protein: RUVC_ORITI
Sequence: MIILGIDPSLVSTGWGVISISGSIVNYIDSGVIKTVSKDSLVLKLGNISLMIEKLITRFNPFHVAMEEVFINKNYSSSVTLIQARGAIMSVIGRYNIDFSEYAPNKIKKAIVGAGKAEKHQVQQMVKLLMHIKKAISKDESDALATAYTASVNHQIKII
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HTPX_BURP1
Sequence: MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATRANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEEHPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYOE_BUCAT
Sequence: MFKNYIEITKPGIIIGNSTLITGGFLFASRHAAFNYVLFIYTILGASLVIASACVFNNLIDIDIDKKMKRTSNRVLSKKLLPVFSVFNFAIFLGVLGLSILGCLVNFISMSLAVFGFFIYVVLYTMFYKRRSFYSTFIGSFSGSTPSVIGYTAVSNTIDICSILLFVIVIFWQMSHFYSISIMRIKDYREAKIPVFSVVKGVAITKKHIFFYVLNFSFFSSLFTFLGYLSYNFLLLSSIVNFYWSFLSYSNIKKNNDKKNARKLFYFSIIVIVFFNFLISIDVFF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2029_ALISL
Sequence: MNIDVATLLSQNDILLLFVVLALGLFIAKVKIGSFQLGSSIGVLITALFMGSLGYTFTADSLNIGFMLFIFCVGIEAGPNFFGIFLRDGKHYLLLVLVVLISAISLSFLTGYYFNLDYGLSTGMMAGALTATPVLVGAKDALNSGLAVLPEGVDFSKVMDNLSVGYAFSYLIGLTSLILLARLLPQLQKQNLQDSAMQIAQERGIGSAGQRKVYLPIIRAYRVGQELIDWTDGKNLRELGIHRQTGCHIERIRRNGILANPDGDYILQQGDEIALVGYPDSHARLDSSFRNGKEVFDRNLLDLRIAEEEIVVKNDNIAGKRLSELNLSEYGCFLNRVVRAQIEMPIEHDIVLAKGDILQVSGEKSKVHHIADKIGFISIHSQVSDLLAFCSFFILGIMFGMITMSFGQVTFGLGNAVGLLISGITLGFLRANHPTFGYVPQGALNMTKNLGLLVFMVGIGLSAGGNIIEYFSEDGLKVLAAALIVSVIPVILAYLVGAYILKMNRALLIGAIIGARTCGPAMDVVNEHARSTIPALGYAGTYAIANILMTVAGTIMILLA
What are the official names of this protein?
Putative transport protein VSAL_I2029.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAX_THEPX
Sequence: MLLVFDVGNTNIVMGIYKGKKLLHSFRISTEKSKTSDEYGMLINQLFEYNGLKLKDVDAVIISSVVPPIMHTLESMTIKYCNTKPLIVGPGIKTGINIKYDNPKEVGADRIVNAVAAYEIYGGPVIVIDFGTATTFCAISKNCEYLGGIIAPGLAISADALFQRTAKLPKIELTKPSTVICKNTVSSMQSGIIYGHVGMVDYIVSRMKEEFAPNAYVVATGGFARMIAEESKTINTVNDMLTLEGLRIIYERNAD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_SHESM
Sequence: MAFTFKQFHIDDLNCGMPVSTDGVILGAWAPLAEAKNILDIGAGSGLLSLMAAQRSQGQITAVELEEKAAAACRYNMTQSPWAKRCQLVHGDIQSVCQLAQYQGYFDHIICNPPYFEHGPKASEQHRAMARHTETLGFTPLLDAISQCLSFEGYASLILPIQSLARFKACLNDTALYLVREVWVKSVENKAANRALLLLSKTEVEPYQRTDLTIRGEDGNYTEQMIELTKDFYLKL
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABIQ_LACLL
Sequence: MSSFFYKEILRMTLRFFTVTDEYIAYLRKFESKVHYQYENNASTYVGVVLKKNDFNYFIPLSSYKKGNPEKDKAMKKRSRIVTRLFEIGNINNPLGYLLHHNMIPVPDSELIPLPLDLKKPKHKMMQKQLIYMKSISEKIENKSEVVYRKAAHEKDGYYLKFSCDFKLLEAKATLYSKKSTFQ
What is the function of this protein?
Toxic component of a type III toxin-antitoxin (TA) system.  An endoribonuclease that is probably sequence-specific.  It is neutralized by its cognate antitoxin RNA AntiQ, which has 2. 8 35 nucleotide-long repeats.  Cannot be cloned in L. lactis subsp.  cremoris strain NZ9000 in the absence of the antitoxin gene; expression in strain NZ9000 even in the presence of antiQ inhibits growth in a bacteriostatic fashion (PubMed:23279123).  Confers resistance to 936 and c2 phages but not P335 phages in L. lactis, causes an abortive infection (Abi phenotype).  Viral DNA is replicated but not cleaved from its concatemeric form, while the viral major structural protein is produced normally in the presence of this protein (PubMed:9835558).  Operon expression in E. coli confers resistance to 3 phages of the Myoviridae family (T4, RB69 and phage 2) and 1 of the Siphoviridae family (T5), but not other tested phages (T1, T3, lambda vir, HK97, Mu and pilH alpha).  The presence of this operon in L. lactis subsp.  lactis strain IL1403 during phage P008 infection alters the viral transcription profiles (PubMed:23813728).
What are the official names of this protein?
Endoribonuclease AbiQ, ABIQ, Toxin AbiQ.
What is the protein family that this protein belongs to?
Belongs to the ToxN/AbiQ toxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1X1_LOXGA
Sequence: ADNKRPIWVMGGMVNSLAQIKEFVGLGLDNSEKDNKWYKQ
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  In vivo, intradermal injection induces dermonecrosis (PubMed:8819009).  Induces, hemolysis, vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LgSicTox-alphaI-1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 2, SMD 2, SMase D 2, Sphingomyelinase D 2.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_PSEPK
Sequence: MSITKYPMTVQGARALEEEHLFLSKTERPRLSQAIGEARELGDLKENAEYHAAREEQGMVEARIRDIEGRLQNSVVIDVTTIPHTGKVIFGTTVVLANTETDEEVTYQIVGEDEADVKQGKLSSGAPIARAIIGKEEGDTVVVKTPSGTVEYEIVEVKHI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: FIBIN_HORSE
Sequence: MVFLKFLWMGFFCYLCQGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDHRRCSQGEGSQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISAGLRDKYELLALTIRSHGTRLGRLKNDYLKV
What are the official names of this protein?
Fin bud initiation factor homolog.
What is the protein family that this protein belongs to?
Belongs to the FIBIN family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.