PharMolix/UniProtQA huggingface dataset:
Protein: AMA1_TOXGV
Sequence: MICSIMGGLRSLRAARPYSHQSNTETKHMGLVGVASLLVLVADCTIFASGLSSSTRSRESQTLSASTSGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPHTYPLTSQASWNDWWPLHQSDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNECGSNTALIAGLAVGGVLLLALLGGGCYFAKRLDRNKGVQAAHHEHEFQSDRGARKKRPSDLMQEAEPSFWDEAEENIEQDGETHVMVEGDY
What is the function of this protein?
Essential microneme protein that plays an important role in host cell invasion.  Part of the moving junction (MJ) complex, a ringlike structure formed between the plasma membranes of the apical tip of the parasite and the target host cell.  During invasion, the MJ migrates from the anterior to the posterior of the parasite, leading to internalization of the parasite into a parasitophorous vacuole (PV).
What are the official names of this protein?
Apical membrane antigen 1, TgAMA-1, TgAMA1.
What is the protein family that this protein belongs to?
Belongs to the apicomplexan parasites AMA1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Initially localizes to micronemes, specialized secretory organelles of apicomplexan parasites important for host cell invasion. Relocalizes to the surface membrane upon host invasion by tachyzoites. Found predominantly on the apical end of the parasite surface. A cleavage product of the large ectodomain is released into the medium by extracellular parasites.
Protein: TRHO_BACC0
Sequence: MATTKPYRVLLYYMYTTIENPEEFAAEHLEFCNSLELKGRILVAKEGINGTCSGTVEQTEKYMEAMNNDPRFDGIVFKIDEADGHAFKKMHVRPRPELVTLRLEDDINPHEITGKYLEPKDFYEAMKQEDTVIIDARNDYEFDLGHFKGAIKPDIESFRELPDWIRENKEVLEGKKILTYCTGGIRCEKFSGWLVREGYEDVSQLHGGIVTYGKDPEVQGELWDGQCYVFDERIAVPVNQKEHVIVGKDHFTGEPCERYVNCANPECNKKILCSEENEAKYLRACSHECRVSPRNRYVIQHELTEEQVAAALEKIEAGK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: BPIB3_RAT
Sequence: MMPGVYALLLLWGLATPCLGLLETVGTLARIDKDELGKAIQNSLVGGPILQNVLGTVTSVNQGLLGAGGLLGGGGLLSYGGLFSLVEELSGLKIEELTLPTVSIKLLPGVGVQLSLHTKVSLHGSGPLVGLLQLAAEVNVSSKVALGMSPRGTPILILKRCNTLLGHISLTSGLLPTPIFGLVEQTLCKVLPGLLCPVVDSVLSVVNELLGATLSLVPLGPLGSVEFTLATLPLISNQYIELDINPIVKSIAGDVIDFPKPRLPVKMPPKEDHTSQVTVPLYLFNTVFGLLQTNGALDLDITPEMVPRNIPLTTTDLAALAPEALGKLPPGQHLLLSLRVMKSPMILLQNKKVTVSIPVTIHVLSSVPQGTPVALFQMNGVMTLNAHLVPSTTKLHISLSLERLTVQLASSFSQPFDASRLEEWLSDVVRAAYMQKLNEHLEVGIPLPKILNVNFANSVVDVIENAVVLTVAP
What is the function of this protein?
May have the capacity to recognize and bind specific classes of odorants.  May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites.  May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received.
What are the official names of this protein?
BPI fold-containing family B member 3, Ligand-binding protein RYA3, Long palate, lung and nasal epithelium carcinoma-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: P30II_HTL1C
Sequence: MALCCFAFSAPCLHLRSRRSCSSCFLRAKSAAFSSARFLRRAFSSSFLFKYSAICFSSSFSRSFFRFLFSSARRCRSRCVSPRGGAFPPGGPRRSRPRLSSSRDSKPSSTVSSSSLSFNSSSKDNSPSTNSSTSRSSGHGTGKHRNSPTDTKLTMLIISPLPRVWTESSFRIPSLRVWRLCTRRLVPHLWGTMFGPPTSSRPTGHLSRASDHLGPHRWTRYRLSSTVPYPSTPLLPHPENL
What is the function of this protein?
p13II increases mitochondrial permeability to monovalent cations, producing a rapid, membrane potential-dependent influx of potassium.  This could involve a channel-forming activity.  Interferes with cell proliferation and transformation and promotes apoptosis induced by ceramide and Fas ligand, probably using the Ras signaling (By similarity).
What are the official names of this protein?
Accessory protein p30II.
What is the protein family that this protein belongs to?
Belongs to the HTLV-1 accessory protein p30II family.
What are the subcellular locations of this protein?
[Isoform p30II]: Host nucleus, host nucleolus. SUBCELLULAR LOCATION: [Isoform p13II]: Host mitochondrion inner membrane.
Protein: Y3753_MYCTA
Sequence: MQPGGDMSALLAQAQQMQQKLLEAQQQLANSEVHGQAGGGLVKVVVKGSGEVIGVTIDPKVVDPDDIETLQDLIVGAMRDASQQVTKMAQERLGALAGAMRPPAPPAAPPGAPGMPGMPGMPGAPGAPPVPGI
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein MRA_3753.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SELO1_DANRE
Sequence: MASVGSRLTRFYISRPGVIARRFLAHAGMDDMGVSLSRSSLERLEFDNVALKKLPLDPSTEPGVRQVRGSCFSRVQPTPLKNPEFVAVSAPALALLGLDAEEVLKDPLGPEYLSGSKVMPGSEPAAHCYCGHQFGQFAGQLGDGAACYLGEVKAPAGQSPELLRENPTGRWEIQVKGAGLTPYSRQADGRKVLRSSIREFLCSEAVFALGVPTTRAGSVVTSDSRVMRDIFYDGNPRMERCSVVLRIAPSFIRFGSFEIFKRADEFTGRQGPSYGHDELRTQMLEYVIENFYPEIHRNYPDLTERNTAFFKEVTVRTARLVAQWQCVGFCHGVLNTDNMSILGLTLDYGPFGFMDRFDPDFICNASDNSGRYSYQAQPAICRWNLARLAEALEPDLPPDRAEQVLDEYLPLYNDFYLSNMRKKLGLLRKEEPEDEMLITELMQTMHNTGADFTNTFRSLSQISCPTQEEAEDESETIKQATELLLHQSASLEELKAANRPSMDPRELAMLVSMAQSNPALFQMISDRGTVSRQLERLSRLKELMDTTEEQLRVKHTEHWSDWIQKYRQRLARECESGVDVKDVQTERVRVMNNNNPHVVLRNYIAQNAIAAAENGDFSEVQRVLKVLEKPFSVQEGLEQPGWMGRGGAAIPGERDETEEEGSNSSGAGARGLVPYDSKPPVWANEICVTUSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation).  May be a redox-active mitochondrial selenoprotein which interacts with a redox target protein.
What are the official names of this protein?
Protein adenylyltransferase SelO-1, mitochondrial, Selenoprotein O, SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLO2_ALKEH
Sequence: MTEIVAIPAFADNYIWLAVDRNRRLAAVVDPGDAEPVEAALRASGLRLSAILITHHHHDHTGGVEELLAAHPVPVYGPADESVPGVSQPLREPDAFEVPGLGLPLRVLDVPGHTAGHIALVADGALFSGDALFAGGCGRLFEGTPEQMYASLGKLAALPEATRVYCGHEYTLANLRFAHQVEPDNPNLTQRLRQAEAARQRGEPTVPSRMADEHATNPFLRAHLPAVRTAAERWSGQTLDEPVAVFAALRRWKDQS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: VES_ECOSM
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASITSIAANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: FRCA_RHIML
Sequence: MAQEPILTARGLVKRYGRVTALDRADFDLYPGEILAVIGDNGAGKSSMIKAISGAVTPDEGEIRLEGKPIQFRSPMEARQAGIETVYQNLALSPALSIADNMFLGREIRKPGIMGKWFRSLDRAAMEKQARAKLSELGLMTIQNINQAVETLSGGQRQGVAVARAAAFGSKVVIMDEPTAALGVKESRRVLELILDVRRRGLPIVLISHNMPHVFEVADRIHIHRLGRRLCVINPKDYTMSDAVAFMTGAKEPPREAIAA
What is the function of this protein?
Part of the high-affinity ABC transporter complex FrcBCA involved in fructose uptake.  Is also a high-affinity transporter for ribose and mannose (PubMed:11466273).  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Fructose import ATP-binding protein FrcA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS6_BURL3
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADKYGSQCIVVAIDAKRVSADGETPRWEVFTHGGRKNTGLDAIEWARKMAELGAGEILLTSMDRDGTKSGFDLALTRGVSDAVPVPVIASGGVGSLQHLADGIKDGRADAVLAASIFHYGEHTVGEAKRFMADQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_PSEPK
Sequence: MYIQVLGSAAGGGFPQWNCNCVNCKGYRDGTLKATARTQSSIALSDDGVHWILCNASPDIRAQLQAFAPMQPARALRDTGINAIVLLDSQIDHTTGLLSLREGCPHQVWCTDMVHQDLTTGFPLFNMLSHWNGGLQWNRIELEGSFVIDACPNLKFTPFPLRSAAPPYSPHRFDPHPGDNLGLMVEDTRTGGKLFYAPGLGQVDEKLLAMMHGADCLLVDGTLWEDDEMQRRGVGTRTGREMGHLAQNGPGGMLEVLDGFPRQRKVLIHINNTNPILDENSPERAEVLRRGVEVAFDGMSIEL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: RS19_GEOTN
Sequence: MGRSLKKGPFCDEHLMKKIEKLNETGQKQVIKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITEDMVGHKLGEFAPTRTFRGHAGDDKKTKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SCPA_CLOAB
Sequence: MTLNINIDNFQGPFDLLLHLIRKNKMDIYDIKIFDITNQYIQYLNEMKEMDLEITSEFIVMAATLIEIKSKYLLPKTKEEEEEKEESDPTKELVSKLVEYKKFKLAADFLKNRELDYGEVFSKKPEIIDDRTEDADNKDILKDITLLDMYKLFEKLMEMYRSRINTNNSLPDKIAPDIYKIEDKMDEISEIIKSNKEIYFSNIINKCSNKIEVVVTFLALLELIKLKDIKVYQSNNFKDIYIERVSAVE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: DARC1_ACIBT
Sequence: MALAREKRAEFSAQKLEPIFEKYPSVKVRWYDVEAFSTKASDIAVFETTSLQDYYFVIDAIRDSEFCTVPYFEFVEIIPAIEDGYVEYES
What are the official names of this protein?
Darcynin 1.
What is the protein family that this protein belongs to?
Belongs to the darcynin family.
Protein: DAPF_TOLAT
Sequence: MLIQFSKMHGLGNDFVVVDGVTQKVFFNAETLKRLGDRHFGIGFDQLLLVEPPYDPDLDFHYRIFNADGSEVQQCGNGARCFARFVRLKGLTNKDRIAVSTVSGRIVLQLEDNDQVTVNMGVPEFEPAKIPFRALKAEKLYLLRVAEQTVMCGVVSMGNPHCVIEVPSVKDAPVETLGPKLESFDRFPERINVGFMEVVSASEINLRVYERGAGETLACGTGACAAVVVGIQQEKLKGRVKVNLPGGSLYISWNGPGSPVYMTGPAEHVFDGQIEL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGPA1_MOUSE
Sequence: MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQSEYGPRTLDNLINPPLSLQETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFLFSHFKKFYLPYIFPNICKENSLYHPVLDIPQIRPKPHYVMIKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKVDKSAEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEDTAITCSDIPCSETVADHDSAIEDGEKREEENGTSTSEHVRNSSWTKNGSYQEAFHVCEEATEQNIQAGTQAVLQVFIINSSNIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKSMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEDTGNEVFGALHEEQPLPRSSSTSDILEPFTVERAKVNKEDTSPKLPPLNSETGGNSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDLGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLSRAHIEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFFSLGLPGATMLIMDFIIAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPALHPNIPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIHQPQSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPVHATGAENDKTEKSVLNCIYKVLHGCVYGAQSFSNPKYFPISLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEESMPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMSDQEKPEEPPTSNECLEDIAVKDGLSLQLRRFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPLCISEKQENDVINAILKQYTEEKEFVEKHFNDLNMKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNRSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH
What is the function of this protein?
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB (By similarity).  May interact with the HLH region of TCF3/isoform E12.
What are the official names of this protein?
Ral GTPase-activating protein subunit alpha-1, GAP-related-interacting partner to E12, GRIPE, GTPase-activating RapGAP domain-like 1, Tuberin-like protein 1, p240.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated to the nucleus, when associated with TCF3/E12.
Protein: KDSB_ECOLI
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_BORAP
Sequence: MRDDQIFNLIEKEKLREKEHIELIASENFTSLEIRQAVGSVLTNKYAEGYPLNRYYGGCSFIDEIETLAILRAKELFGAKYANVQPHSGSQANMAAIMALINPGDRILGMQLSHGGHLTHGSRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIARDCRPNLIIAGASSYSREIDFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIILSGKDFNKLVTFNGKEKTLSNAVNSTVFPGTQGGPLVHVIAGKAIAFREALQENFKEYISKVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSSLDLTGADAEKLLERVNITLNKNAIPFDKKSPALASGIRIGGAAITSRGLNESDSLNVAKFIVRALKTRSDIELKQIKKEVVRFIRDFDMP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_LEGPL
Sequence: MKKNIKKIALAYSGGLDTSIMIPWLKEHYEHAEVIAVICDLGQQEDLDAIKNKALKSGASKAYVVDVKNEFAIQYLWPLVKSGALYEDQYILGTISRPLIAQKLVEIALTEQVNAVAHGATGKGNDQVRFEYSLKALAPQLEIIAPWRAWDIKSRQEAIVYAKAHGIEVPVTPKAPYSRDHNIWYISHEGGVLEDPSQEMPDDVLLMTSPVSQAPDEEEMIILDFKKGVPVALNEQKLSPVALLNSLNQKAGQHGIGVADIVENRLVGMKIRGIYEAPAAAVLYKAHKLLESLCLTRSTLHLKQSLQQTYANLVYEGRWFSQTKQALDAFIDVTQQHVTGRVKLKLFKGNIIPAGMHSPYSLHHPALATFEEDNVYNQKDAEGFINLFSLSAKIYSQVHQGGNYD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_PSEPK
Sequence: MMDINEIREYLPHRYPFLLVDRVTDLDFEAQSIRAYKNVSINEPFFNGHFPAHPIMPGVLIIEAMAQAAGILGFKMLDAKPADGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSRKSMIWKFECRALVDGKPVCSAEITCAERSL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1666_ARATH
Sequence: MGSEQDQRKRWGGCLGVFSCFKSQKGGKRIVPASRIPEGGNVSASQPNGAHQAGVLNNQAAGGINLSLLAPPSSPASFTNSALPSTTQSPNCYLSLAANSPGGPSSSMYATGPYAHETQLVSPPVFSTFTTEPSTAPFTPPPELARLTAPSSPDVPYARFLTSSMDLKNSGKGHYNDLQATYSLYPGSPASALRSPISRASGDGLLSPQNGKCSRSDSGNTFGYDTNGVSTPLQESNFFCPETFAKFYLDHDPSVPQNGGRLSVSKDSDVYPTNGYGNGNQNRQNRSPKQDMEELEAYRASFGFSADEIITTSQYVEITDVMDGSFNTSAYSPSDGQKLLRREANLLSQTSPKSEADLDSQVVDFQSPKSSNSYKDHKQRNRIHADEEALLSRVGSVKGSRSYHISSSDAEVEYRRGRSLRESRENRHRKA
What are the official names of this protein?
Uncharacterized protein At1g76660.
Protein: HISZ_DEHMB
Sequence: MIARCKGCSDLLPEDMLRFRYIESIFHDSCITWGYEEVRTPMLEYLSLFTSSGTLTPQMLKRVYSFLDWDGWSGERVVLRPDGTIPAARLYIDSLQEMDVARLCYTSNIFRFDETGKKSRENWQLGAELIGVTSPEANAELITLALETLARLGFEDVELRLSHAQLIKAVLAQLEPNADEQHKIFDQLLDGDIALMSRLETEKPELFRTLKLLMENKGTSASFLKNVMAMAGTAGGELEEPLNDFIAGVDVLDKLGVSYQIDLASGKGFEYYTGVIFHLFVNGEHVGGGGRYDKLIPLLGGPDKPAAGFALYLNRLIPMIDAEDMYDMVEEKILIKYQGDNLKTAYEIANLIRECGISAELFYPGVDTAAYGWAVTVKAEDCYEVTDLIEDKTLELKEQSEVIYLLNGEEDA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF41_DANRE
Sequence: MGYDVTRFQGEVDEDLLCPICSGVLEEPVRAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKRPVTCEEGCGLEMPKDEMPNHNCIKHLRSVVQQQQTKIADLEKTAAEHKHQLAEQKRDIQLLKAYMRAIRSANPNLQNLEESIEYNEILEWVNSLQPARVTRWGGMISTPDAVLQAVIKRSLIDSGCPLSIVNDLIENAHERNWPQGLATLETRQMNRRYYENYVAKRIPGKQAVVVMACENQHMGEDMILEPGLVMIFAHGVEEIL
What is the function of this protein?
Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins.
What are the official names of this protein?
E3 ubiquitin-protein ligase NRDP1, RING finger protein 41, RING-type E3 ubiquitin transferase NRDP1.
Protein: AMP1_CAEEL
Sequence: MAPPHPRDPSTAANYEQVTVSHYALKWKVDFEKKHIAGDVSITLDVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQTTDRVAPYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETEKILKVAEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFITPTLLAGDRSLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMYGELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVILDNIDWNLWLHKAGLPPKPKYDSTPMQACKDLAAKWTTEGSEAPTDGEVFAKMSNSQKLAVLDAVRVNKTMFGDRMPALTATYKLDQAKNAELKFSWLMLGLETKWSPIVDASLAFALAVGRMKYCKPIYRSLFGWSATRDRAISQFKANIPNMHPITVKAIQSLLK
What is the function of this protein?
Aminopeptidase which preferentially removes N-terminal Arg and Lys residues from peptides and proteins.
What are the official names of this protein?
Aminopeptidase ltah-1.1, Aminopeptidase-1, AP-1, Arginine aminopeptidase 1, Leukotriene A4 hydrolase homolog ltah-1.1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_NEIGO
Sequence: MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPARITGTKAFYQRQLAVAVKRARFLALLPYTDQHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GPSB_STAA1
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: KCH_ECOLI
Sequence: MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYLSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSDNDELETKADSKESAQK
What is the function of this protein?
K(+)-specific ion channel.  May play a role in the defense against osmotic shock.
What are the official names of this protein?
Voltage-gated potassium channel Kch.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.