PharMolix/UniProtQA huggingface dataset:
Protein: SYP_METS3
Sequence: MVENFSEWFHDILEEANITDSRYPIKGMAVWMPYGFQIRKYTTNLIKEVYDRDHEEVLFPLLVPEAELAKEGLHVKGFEDEVYWVTHGGKTQLNEKLALRPTSETSIYPMYSLWIRSHIDLPLKYYQIVNTFRYETKHTRPLIRVREITTFKEAHTAHASKEEADIQVQEHIENYKEIFDTLGIPYTLTKRPEWDKFPGADYTMAFDAIMPDGKTLQIGTIHNLGQTFAKTFDITFEDKDGEHKLVYQTCAGLSDRVIASAIGIHGDEKGLRLPPEISPKQITIIPILFKKGKEEVLAKCEELKKEFEAAGLRVNIDNRDIRPGKKFYDWELKGTPIKLELGPRDLENNKTIAMRRDQLEKIELDLDENLVSNVIRLIDELNENLAESAKEFHTDHIKFASDIDEVRKLIEEGNVVAVNWCGDTDCGEKIEEITGYSVLGIYEELEEAGKKCILSDEDAKYVALIAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI2BE_SCHPO
Sequence: MPPSKGLNGKLEKPKHALQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQEVYVFCCAHAGQIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFILVSGDVVSNVPLNEVLKEHRKRREDDKNAIMTMVVREASPFHRTRARTESSVFVIDKKTSQCVHYQANERGKHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTENFDYQDIRKDFVYGVLTSDLLGKKIHCHVAKENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLLNQTFSYQRHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNCSIDSAFLWEDVVIGDNCRIGKAILANSVKIGNNCSIEDGAIVAAGVVIGDNTIIEKNKRLTTFESHSQGTLNDPSLVGIGGRGQEYHAEEDSDDEGEFMEASGLIESTNELHLSDSESSETSSSSEEDMEFIPFSARRDSANTINSEDFDEGDFNKEAQQSLERAFEENHQIDIAALELNTLRMAMNANYHEVRSAIVLALLRRIMHLDVSPKEALAKVMTRWGPLLAKLTFSHEEQVDNVLTLQKYCVRLSMTRHFLQLLGYFYQLEIAEENAIQEWYSDPRSSEGELAALRDAGGKQFVDWLNTAESESESEEGSE
What is the function of this protein?
Subunit of the guanine nucleotide exchange factor for eIF-2.
What are the official names of this protein?
Probable translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B gamma/epsilon subunits family.
Protein: RBSA3_RHIME
Sequence: MVTELANLKSISKSFGGIHALRSVNFDVRPGEVHALLGENGAGKSTLMRVLGGEIIPSQGEVVINGKRTELRDPRDARALGIVVIHQELALAPDLSVAENIFLGELPTLISRFSLRRRAKQLIDRLGFDIDPGRLVGTLSVAHQQVVEIAKALSQDIKIIVFDEPTAVLGAQDAMKLHQIIRGLRDRGVGIVYISHRLDEVFDIADRMTVMKDGETVGTVATTDVKIDDIIRMMVGRPIANMFPERSQRTIGAELLNVKKLNAGRMVRDVSFSVRAGEIVGLGGLIGSGRTEVARAIFGADPLDSGTISLKGKALKLKSPRDAVKAGIGLVPEDRKEHGVVIDKPIRVNATMARMSSVVNALGFLKPALERTDVTALGKSLRLKASSIDAPVSSLSGGNQQKVVLAKWFHAGGDVIILDEPTRGVDVGAKAEIYALINKLAEDGKAVLVISSEHQELFGLCDRVLAMGQGQIRGELTPSNYSEENLLGLSMMGGARASNQGSQV
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BRXL1_ORYSJ
Sequence: MLTCIACSKQLAGGAPPLREQSDDADDAAVARGAGECATPSTRQAIKALTAQIKDMALKASGAYRHCKPCAGSSSSSPAAGARRHHPYHAYADSGSDRFHYAYRRAGSGGDATPSVSARTDFLAGDEEEEEEEEEEEGTTADGSEDDEAKEWVAQVEPGVLITFLSLPEGGNDLKRIRFSREIFNKWQAQRWWAENYEKVMELYNVQRFNQQTPLPTTPKSEDESLKEDIPATPPLNSERLPHTLHRSLTGGRTTGYGQPDSLGHQHNLGNGHRQQHHHCYTGHQCYGSVGLASTPKLSSISGAKTETSSMDASMRSSSSPEEVDRSRELSVSVSNASDQEREWVEEDEPGVYITIRALPGGIRELRRVRFSREKFSEMHARLWWEENRARIHDQYL
What are the official names of this protein?
Protein Brevis radix-like 1, OsBRXL1.
What is the protein family that this protein belongs to?
Belongs to the BRX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KVD12_HUMAN
Sequence: MDMMVPAQLLGLLLLWFPGSRCDIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQANSFP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 1D-12, Ig kappa chain V-I region Wes.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: Y1752_WOLSU
Sequence: MEKLVESLSSNQKRNQALLHPFEGNEALLELTKGRLGNEEPCHVKGAQGEEYVILPKHLLLGLVNLLQKGREERVKLNLERDILQQMPIDFEDVWEVALQEIHRENANPSYVDTKRLIKEIKRRHPNLFFQLGDLFGRAKEEMLD
What are the official names of this protein?
UPF0763 protein WS1752.
What is the protein family that this protein belongs to?
Belongs to the UPF0763 family.
Protein: EFP_METPB
Sequence: MKVIASTLRKGNVVDKDGKLYVILTAENIHPGKGTPVTQLDMRRITDGVKISERYRTTEQVERAFVEDRDHTFLYQDGEGYHFMNPENYEQLAVPEDVVGDAAPYLQEGMVVTLSTHNGVPLAIELPQRVTLEIVETEPVTKGQTASSSYKPAILSNGVKTSVPPHITTGTRVVIMTADGAYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDGF1_HUMAN
Sequence: MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGICLSIQSYY
What is the function of this protein?
GPI-anchored cell membrane protein involved in Nodal signaling.  Cell-associated TDGF1 acts as a Nodal coreceptor in cis.  Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714).  Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).
What are the official names of this protein?
Teratocarcinoma-derived growth factor 1, Cripto-1 growth factor, CRGF, Epidermal growth factor-like cripto protein CR1.
What is the protein family that this protein belongs to?
Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Released from the cell membrane by GPI cleavage.
Protein: UGTP_BACAC
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPADHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CBIM_RUMCH
Sequence: MKRVSVKNYLVCLLIAVCAIFVFPANASAMHIMEGYLAPGWCISWGVMCMPFLVIGFFSIKKKIEVSSKNLTLLAMCGAFAFVLSALKMPSVTGSCSHPTGVGLGAVLFGPTAMSVIGAIILLFQAILLAHGGITTLGANVFSMAIVGPLVSFGVFKLSKRWGAKAGLAVFLAVFFGDLMTYVITSVELAMAYPDATGSFMVSLGKFISIFGFTQVPLAVCEGLLTVVIYNVLAKYSAKELKALSAIY
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS7_PSEMY
Sequence: MAERTAFVERNTLETQVKVSINLDGTGKAKLDIGVPFLEHMLDQIARHGLIDLDIECKGDLHIDDHHTVEDVGITLGQAFAKAVGDKKGMTRYGHSYVPLDEALSRVVIDFSGRPGLQMHVPFTRAVVGNFDVDLFQEFFQGFVNHALVSLHIDNLRGHNTHHQIETVFKAFGRALRMAVELDPRMAGQMPSTKGCL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDT_ARATH
Sequence: MNGGDVTVAGSDDLKSPLLPVVHNDEPFERQTVGQQLRTIFTPKNCYIALGPLLCAVVCLCVDLGGDETTTARNMLGVLVWMFAWWLTEAVPMPITSMTPLFLFPLFGISAADDVANSYMDDVISLVLGSFILALAVEHYNIHRRLALNITLVFCVEPLNAPLLLLGICATTAFVSMWMHNVAAAVMMMPVATGILQRLPSSSSTTEVVHPAVGKFSRAVVLGVIYSAAVGGMSTLTGTGVNLILVGMWKSYFPEADPISFSQWFFFGFPLALCIFVVLWCVLCVMYCPKGAGQALSPYLHKSHLRRELDLLGPMNFAEKMVLAVFGGLVVLWMTRNITDDIPGWGRIFAGRAGDGTVSVMMATLLFIIPSNIKKGEKLMDWNKCKKLPWNIVLLLGAGFAIADGVRTSGLAEVLSKGLVFLETAPYWAIAPTVCLIAATITEFTSNNATTTLLVPLLIEIAKNMGIHPLLLMVPGAIGAQFAFLLPTGTPSNVVGFTTGHIEIKDMIKTGLPLKIAGTIFLSILMPTLGAYVFASMGGV
What is the function of this protein?
Putative carrier protein indirectly involved in the uptake of malate and fumarate to the vacuole, probably by regulating the energization across the tonoplast.  Uptake of malate to vacuoles is inhibited by citrate and by the uncoupler carbonyl-cyanide m-chlorophenylhydrazone, but seems to be not affected by sodium.  Critical for pH homeostasis.
What are the official names of this protein?
Tonoplast dicarboxylate transporter, AttDT, Sodium-dicarboxylate cotransporter-like, AtSDAT, Vacuolar malate transporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: RRF_PSYA2
Sequence: MIKEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLSGVMVSYYGSDTPLNQVASVNVEDSRTLLVQPFDRTMVQAIDKAIREADLGLNPMTADVIRVPMPALTEETRRDMQKLARGEAENSRVSIRNIRRDMMNDIKELAKEKEISEDDEHRASDDIQKITDKYIETIDSRLSKKESDLMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDCC_ECOLU
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTLSMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y988_THET2
Sequence: MLTFRVEKLVPGGYGLARTERGVVLVKGALPGELVRGEPKRKKGALFLEAPEILEAHPGRYPEPLPPSADLPLAYEAQLPLKEALVRDALERVAKLEAPLAPIRPSPRPLAYRTAAQYARHPLGGLAYRLPESHELHRLEKDPLLAEPLAWAFDVLKLWPLPVEEVALRGSLLEGKVLLGLVGGVPEALKRPAKALVQEGFAGVVWAEPSPKGRFRGRVTPLAGERTLLEAFGPLKATVSVESFSQVNPLAAGALLEEARTLVFGGRRALELYAGSGLFSLLLSPRYEEVVAVEISKEAVRRGEMDRKRLGAENVRFLRMDARKAEALGAFDLVVVDPPRAGLPPEVRAYLLRARPREILYVSCDPATWARDVGALVQGGYRLAFARPYDFFPFTHHVEVLSLLRL
What are the official names of this protein?
Uncharacterized RNA methyltransferase TT_C0988.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: C13A7_CAEEL
Sequence: MSFSILIAIAIFVGIISYYLWIWSFWIRKGVKGPRGLPFLGVIHKFTNYENPGALKFSEWTKKYGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQGDPNKNKRVPLVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQEFTMDIIGKMAMGQEKSLMFRNPMLDKVKTIFKEGRNNVFMISGIFPFVGIALRNIFAKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDARSTVDFFEGEAEQDFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESGDELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETVIPLKLVGTATIAPSSVLLKLKSRF
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Putative cytochrome P450 CYP13A7.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DAPF_SALTY
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCLX_CHICK
Sequence: MGPLWALRVAGALSVAGVLAGHDGSQRAGQPAALDAGTRGDGVGHDRGVDCREVRKRNSSERCRFVRGTPDCRLDGGFLDYLGGAFCTFPSSLLPLSVSLYALWLLYLFVILGVTAEKFFCPNLSAISTNLKLSHNGLGVVGHSLTPALHGVTFLAFGNGAPDIFSAVVAFSDPRTAGLAVGAIFGAGIFVTTVVAGGIALVKPFAAASRPFLRDVIFYMVAVFLTFLVLYFGYITLGEALGYLGLYVFYVFTVVLCTWIHRWQRGDGPPPPGPWEPAIPTDAEEQESSGTNCGDYGEEYRPLLPYHETSLHILSTALSPLDKHKWRRKPWYWRLFKVLKVPVELVLLLTVPVVDPDKDDLNWKRPLNCLHIVTGPLLCIFTLKSGAYGLYQIQGVFPVWALVALAGSVLAIIVFVTTHNEEPPKYHCVFAFLGFLSSAMWINAAATELVNILRTLGIIFELSNTVLGLTLLAWGNSIGDTFSDLTMARQGYPRMAFSACFGGIIFNILVGVGLGCLLQMTNSQMVVKLEPDSLLVWILAGALGLSLVFSFVAVPAQCFQLGKAYGTCLILYYLVFLCVALLTEFRVIHLAAT
What is the function of this protein?
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion (By similarity).  Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity).  Involved in B-lymphocyte chemotaxis (PubMed:27328625).
What are the official names of this protein?
Mitochondrial sodium/calcium exchanger protein, Na(+)/K(+)/Ca(2+)-exchange protein 6, Sodium/calcium exchanger protein, mitochondrial, Sodium/potassium/calcium exchanger 6, Solute carrier family 8 member B1.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TILS_CHLTA
Sequence: MITRLFENDKQLEGFFSSLDKKKKYLLALSGGSDSLFLMYLLKSRAIFFTAVHVDYGWRETSYQEASDLAALCEQEQIPFILDRPEATDPMDSRDIENAARRYRYELFYRLCKEKCFSGVFLGHHADDQAETILKRVFEGAHLGNLKGMSAQVMYRDVALLRPLLHIPKHKIVEALDSHQVQYVQDITNCNERFLRARMRERLFPYLQDVFGKNIRDPLLSLAGDSAELREYLDQQTAPFLLRVVDNERGKLLPIEQELLKTPFLAKWVCKQFFLNERLVASKSFLQTVYDHLMTGSTARLRLRNRTVLVKARGVIIESIY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_PROMA
Sequence: MENKLLSSQEIQELRKSLPTWEEAEGKLVKRFKFTNFIEAFGFMTKIAIISESLSHHPEWTNIYSEVIIRLSTHDMGGITMLDYKLAKAIDAIKYE
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PBL25_ARATH
Sequence: MSCFSCFSSKVLDNEGSSMPAPYKQPNSPKRTTGEVVAKNANGPSNNMGARIFTFRELATATKNFRQECLIGEGGFGRVYKGKLENPAQVVAVKQLDRNGLQGQREFLVEVLMLSLLHHRNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLLDLEPGQKPLDWNTRIKIALGAAKGIEYLHDEADPPVIYRDLKSSNILLDPEYVAKLSDFGLAKLGPVGDTLHVSSRVMGTYGYCAPEYQRTGYLTNKSDVYSFGVVLLELISGRRVIDTMRPSHEQNLVTWALPIFRDPTRYWQLADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPLMSDVITALSFLGASSNSSNTGSNHLQQNRSNKYQDAVQWDSSPRYANSQM
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL25, PBS1-like protein 25.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TBX4_CANLF
Sequence: MLQDKGLSESEEAFRAPGSALGEASASNAANAPEPALAAPGLSGAALGSPPGPGADAAAAAAAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVSTQLSAKPDVSPLHGAHQALQHYQYENGAHMQFAAAEPQDLPLNTFPAQRDSSLFYHCLKRRDSARHLDLPCKRSYLEAPPAVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEITGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQSFPTHFTATTMMPRLPAISAPSSQPPGNSHFSVYNQLSQSQVRERGPTTSFQRERGLPSVCERKPPSPHLNAANEFLYSQSFSLSREASLQYHSGMGTVENWTDG
What is the function of this protein?
Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
What are the official names of this protein?
T-box transcription factor TBX4, T-box protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: H8J01_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYASESEEKEFPREMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWRVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1b, U3-TRTX-Hhn1b, Hainantoxin-VIII-10, HNTX-VIII-10.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_CARHZ
Sequence: MERTFIMVKPDGVQRGLVGEIISRFEKRGFKLVGLKLMQISRELAETHYGEHKGKPFFEGLLNFITSGPVVAMVWEGKEVIATAREMMGATNPLKAQPGTIRGTYGIDVGRNVIHGSDSPESAAREIALFFKEEELLSYEKTLDTWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXY2_ARATH
Sequence: MAISLATAYISPCFTPESSNSASPSRTLSSVRLPSQIRRFGSVQSPSSSTRFAPLTVRAAKKQTFNSFDDLLQNSDKPVLVDFYATWCGPCQLMVPILNEVSETLKDIIAVVKIDTEKYPSLANKYQIEALPTFILFKDGKLWDRFEGALPANQLVERIENSLQVKQ
What is the function of this protein?
Thiol-disulfide oxidoreductase that poorly activates chloroplastic malate dehydrogenase (NADP-MDH) and fructose-1,6-bisphosphatase.  Provides reducing equivalents for peroxiredoxin Q.
What are the official names of this protein?
Thioredoxin Y2, chloroplastic, AtTrxy2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant Y-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: MSA_STAAC
Sequence: MKYLILSLVANLLVFGVLSAIGLNINILAAMMIVLVIPIMISGILFFKTNIDKTYIFFNIIFIDFYYYIYNVHLMTLPKFNNYIKAEMMELEDIDVLITSKDFGFDEILFYTLYLLLILIVLYYLKKQVKHKI
What is the function of this protein?
Accessory element involved in the expression of sarA and several virulence factors.  Modulates SarA production and/or function in a strain-dependent manner.  Affects the transcription of the accessory gene regulator (agr) and genes encoding virulence factors including alpha toxin (hla) and protein A (spa) (By similarity).
What are the official names of this protein?
Protein msa, Modulator of SarA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HXC5_MOUSE
Sequence: MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C5, Homeobox protein Hox-3.4, Homeobox protein Hox-6.2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.