PharMolix/UniProtQA huggingface dataset:
Protein: RS4_STRCO
Sequence: MANQPRPKVKKSRALGIALTPKAVKYFEARPYPPGEHGRGRKQNSDYKVRLLEKQRLRAQYDLSERQLVRAYERASKTNMKTGEALVIELERRLDALVLRSGIARTIYQARQMVVHGHIQVNGQKVDKPSFRVRPDDVVQVRERSKEKTLFTIAREGGFAPDGETPRYLQVNLKALAFRLDREPNRKEIPVICDEQLVVEYYAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RRAA_HAEIE
Sequence: MFIDTSELCDLYAEQVDVVEPIFSSFGGVSNFYGKVTTVKCFESNGLIAEVLEENGEGRVLVIDGGGAVRRGLIDAELAQLAVDNGWEGIIVYGAVRQIQQLENLDIGIHALAPIPVSADESSAGESDIPVNFGGVTFFPEDYIYADLTGIILSQEPLDLED
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_LACLA
Sequence: MLVPKRVKHRREFRGKMRGYAKGGDTISFGEYGLQATTSHWITNRQIEAARIAMTRYMKRNGQVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGVVMFELGGVDEATAREALRLASHKLPVKTKFVKRGEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FIS1_MOUSE
Sequence: MEAVLNELVSVEDLKNFERKFQSEQAAGSVSKSTQFEYAWCLVRSKYNEDIRRGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGLIGLAVSKSKS
What is the function of this protein?
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering (PubMed:23283981).  Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission (PubMed:23283981).  May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event (By similarity).  Also mediates peroxisomal fission (By similarity).  May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis (By similarity).  Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein, FIS1 homolog, Tetratricopeptide repeat protein 11, TPR repeat protein 11.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Protein: DNAB_HAEIN
Sequence: MASQPQIKSSDKKTAQVSIPPHSTEAEQAVLGGIMLSNQHWDGIAERVIADDFYTFQHRLIFTEMEHLMRNQSPIDLITLDQALRSRGVSDEVGGFAYLAELSNNTPNAINILAYADIVREKAILRELISVGNRIAENSYSPKGQDIKLILDEAEREVFAIAEKRTTSSEGPQNVINVLESTIEKIDILSKLENHSGVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEMPAEQIMMRMIASLARVDQTKIRTGQNLDEIEWNKIASVVGMFKQKNNLFIDDSSGLTPTDVRSRARRVYRENGGLSMIMVDYLQLMRAPAFSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRTLEQRGDKRPVNSDLRESGSIEQDADLIMFIYRDEVYNDNSEDKGVAEIIIGKQRNGPIGRVRLKFNGQFSRFDNLAEQREYRDDY
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: SH3LA_XENLA
Sequence: MVIKVFLASSSSFVTIKKRQQEVLQFLEANRIEYEEVDITMLEEMRQWMYKNIPKDRLPGQGNPLPPQIFNDNAYCGDYESFFESKESNTVFLFLQLKARPAQKEL
What are the official names of this protein?
SH3 domain-binding glutamic acid-rich-like protein 2-A.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAY_VIBVU
Sequence: MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNEGPESHFSKRGTPTMGGVMILAAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALIVAFALYAYGKDTAATQLVVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELVVVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: M030_ARATH
Sequence: MFQFAKFSKSKERRLATELGYGFPIGDPWITDGISPWPFASESVLPSQCPGIHPMHSFRSCTQGTLNTTKISMKLTISDCGFEPLTEGFTVLHSTRATTCYHFLFNS
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00030, ORF107a.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CSPG_ECOLI
Sequence: MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRTLNENQKVEFSIEQGQRGPAAANVVTL
What are the official names of this protein?
Cold shock-like protein CspG, CPS-G.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_MAGMM
Sequence: MADLKQVYHDKVVPELQAKFGYSNVMQVPRLQKIVVNMGVGEAIADKNFLNNAIGNLEAITGQKAQTTYAKKSIAGFKLREGQAVGCRVTLRRRQMWEFLDRLINAALPRVRDFRGVSEKAFDGRGNYTMGIKEQIIFPEIDYDKVDKVRGMDICIVTSAKTDDEARQLLAGFNMPFRKKEGNNG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DPEP1_BOVIN
Sequence: MWTGWWLWPLVAVCTADQFRDNAVRLMQSTPVIDGHNDLPWQLLKRFNNQLQDPRANLTSLNGTHTNIPKLKAGFVGAQFWSAYTPCDTQNKDSVKRTLEQIDVIQRMCQLYPETFLCVTDSAGIQQAFQEGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYLTLTHSCNTPWADNWLVDTGEDEAQSQGLSSFGQSVVKEMNRLGVIIDLAHVSVATMEAALQLSKAPVIFSHSSAYSVCRHRRNVPDHVLQLVKQTGSLVMVNFYNDYVSCKAEANLSQVADHLDYIKKVAGAGAVGFGGDYDGVSRLPSGLEDVSKYPDLVAELLRRQWTEEEVRGALAENLLRVFKAVEQASDHKQAPGEEPIPLGQLEASCRTNYGYSGAPSLHLQPGTLLASLVTLLLSLCLL
What is the function of this protein?
Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
What are the official names of this protein?
Dipeptidase 1, Beta-lactamase, Microsomal dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Note=Brush border membrane.
Protein: PYRC_PSEAE
Sequence: MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSTEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNIFEALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKEAACGCAGCYSAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREEWQAPASLPFGDFDVVPLRAGETLRWKLLEAGA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TUS_SALPK
Sequence: MSRYDLVERLNGTFRQIEQHLAALTDNLQQHSLLIARIFSLPQVTKEAEHAPLDTIEVTQHLGKEAEALALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDNATQLDLENQIQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLTLINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQDIAALPQQARLKIKRPVKVQPIARIWYKGQQKQVQHACPTPIIALINTDNGAGVPDIGGLENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ERWT9
Sequence: MSRTIFCTFLQRDAEGQDFQLYPGDTGKRIFNEISKEAWSKWMAKQTMLINEKKLSMMNPDDRKLLEQEMIKFLFEGHEVHIEGYTPPEE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PPARG_XENLA
Sequence: MVDTEMPFWSNLNFGMNSMDMSALEDHCQPYDIKPFTTVDFSSINSHYDDILDEKTFLCRNDQSPIDYKYDLKLQECQSSIKLEPPSPPYFSDKPQCSKAFEDTPNSFIAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYERCDLNCRIHKKSRNKCQFCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADQRVLAKHLYDSYVKSFPLTKAKAPGHPDGQSHRQNSRGYTRHELADDGGGSDQGAVREPRAEQGGGDSNLPALSVALRGGVREITEFAKNIPGFVSLDLNDQVTLLKYGVHEIIFTMLASLMNKDGVLVAEGQGFMTREFLKSLRKPFSDFMEPKFEFAIRFNSLELDDSDLAIFVAVIILSGDRPGLLNVKPIEDIQDSLLQALELQLKLNHPDSAQLFAKLLQKMTDLRQVVTEHVQLLQLIKKTEADMCLHPLLQEIYKDLY
What is the function of this protein?
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription.  It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.  Key regulator of adipocyte differentiation and glucose homeostasis.  May play a role in the regulation of circadian rhythm (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KN5C_ORYSJ
Sequence: MSSRQDKEKSVNVQVLLRCRPFSDDEVRSNAPQVITCNDYQREVAVTQTIAGKQIDRVFTFDKVFGPTAKQRDLYDQAIIPIVNEVLEGFNCTIFAYGQTGTGKTYTMEGECRRAKSGPKGQLPADAGVIPRAVKQIFDTLESQNTEYSVKVTFLELYNEEITDLLAPEEISKAALEERQKKPLPLMEDGKGGVLVRGLEEEIVTNASEIFSLLERGSAKRRTAETLLNKQSSRSHSLFSITIHIKEATPEGEELIKCGKLNLVDLAGSENISRSGAREGRAREAGEINKSLLTLGRVITALVEHLGHVPYRDSKLTRLLRDSLGGRTKTCIIATVSPSVHCLEETLSTLDYAHRAKSIKNRPEVNQKMMKSTLIKDLYGEIDRLKAEVYAAREKVGVYIPKDRYQQEENERKAMADQIEQMTTSLEANQKQINDLQEKYDSELQHSADLSKKLEATEKCLDHTSNLLSTTKEDLKQAQYNLKEKDYIISEQRKAENALIQQACLLRSDLEKSNRENAALYSKIARGDKLNAANRSVVNSFQADLASKLDILSTTLATSIDQQNKHLKSVENLCKSCVDSHDTATSEIKKKILASKALYMSHMEAFQNVVLLHKANSNSTLEDISSLSAASCCSLDQLLACVEGEAQKIFGDIQNLLADHRSEVAHFTQELRESFRISLDRTKDMSSFILGLFDKYVEETSKLQSHSNHTHEAQVKSLEDFQKAYEEQSKSEEQKLLADITSLVSKHVTRQRELVGGRLNSLGDAARGNKAFLDEHTSAMEVVTKDAKRKWEMFAEQAENDCKVGSNFSAAKHCRMETILQECACTVDTAAQQWKASHATVNDLCRKQIAEVEALVRSAIETNEQHEAEIASSRATAEEHASNSSKDLLQDVDNMLQEARNSSSRVVSTVEAHLGESQHLQESHSSHTAGINTHADNAFQSSYKDYEPTGETPVRSEPEVPSKDAIESLRAMPMESLMDEFRENHPYEPSKDRRPSLIPRSPLATINN
What is the function of this protein?
Responsible for microtubule translocation.  May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity).  Plays an essential role in stabilizing the mitotic spindle.  Required during mitotic cytokinesis (By similarity).
What are the official names of this protein?
Kinesin-like protein KIN-5C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Microtubule-associated.
Protein: PRMA_STRM5
Sequence: MPFLELTLRCTEATQPRYENALEDVGALAVTLLDAEADTSNEQAILEPGVGETPLWDTLVLSALFPADSNALLLLAALEAFDPELDWSGGSFRAVEDEDWERAWLDQFQPMDFGSRTWIVPWNHELPEAAQAADAAVVRLDPGLAFGSGTHPTTALCLRWLDQLAVDGLLQGQRVLDFGCGSGILALAALKLGAAEAIGVDNDPQALVATADNAERNGEQARMHVYLPQDEPVATYPVVVANILASALDALAELLAARVAAGGRIALSGILHGQEGELLQRYAPWFDDLQATQDGDWMRITGVRRA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIG_HUMAN
Sequence: MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357).  May be implicated in the folding, transport, and assembly of proteins.  May play an important role in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase G, PPIase G, Peptidyl-prolyl isomerase G, CASP10, Clk-associating RS-cyclophilin, CARS-Cyp, CARS-cyclophilin, SR-cyclophilin, SR-cyp, SRcyp, Cyclophilin G, Rotamase G.
Protein: RL7_STRPN
Sequence: MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAADAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVATAEAEEIKAKLEEAGASVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MRE11_HUMAN
Sequence: MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFRHREQKEKTGEEINFGKLITKPSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAEQMANDSDDSISAATNKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLETSTRSRNSKTAVSASRNMSIIDAFKSTRQQPSRNVTTKNYSEVIEVDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDDDDDPFMNTSSLRRNRR
What is the function of this protein?
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289).  The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11 (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289).  RAD50 may be required to bind DNA ends and hold them in close proximity (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289).  This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289, PubMed:30612738).  The complex may also be required for DNA damage signaling via activation of the ATM kinase (PubMed:15064416).  In telomeres the MRN complex may modulate t-loop formation (PubMed:10888888).
What are the official names of this protein?
Double-strand break repair protein MRE11, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Chromosome. Note=Localizes to discrete nuclear foci after treatment with genotoxic agents.
Protein: ARGL1_CHICK
Sequence: MGRSRSRSSSRSKHTKSSKHNKKNRSRSRSRSREKERARKRSKSRESKRNRRRESRSRSRSNTAPSSRRDRERERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLKIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKSQD
What are the official names of this protein?
Arginine and glutamate-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the UPF0430 family.
Protein: COPZ_STAAC
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOXB_SOLLC
Sequence: MSLGGIVDAILGKDDRPKVKGRVILMKKNVLDFINIGASVVDGISDLLGQKVSIQLISGSVNYDGLEGKLSNPAYLESWLTDITPITAGESTFSVTFDWDRDEFGVPGAFIIKNLHLNEFFLKSLTLEDVPNYGKIHFVCNSWVYPAFRYKSDRIFFANQAYLPSETPQPLRKYRENELVALRGDGTGKLEEWDRVYDYACYNDLGEPDKGEEYARPILGGSSEYPYPRRGRTGREPTKADPNCESRNPLPMSLDIYVPRDERFGHVKKSDFLTSSLKSSLQTLLPAFKALCDNTPNEFNSFADVLNLYEGGIKLPEGPWLKAITDNISSEILKDILQTDGQGLLKYPTPQVIQGDKTAWRTDEEFGREMLAGSNPVLISRLQEFPPKSKLDPTIYGNQNSTITTEHVQDKLNGLTVNEAIKSNRLFILNHHDIVMPLLRKINMSANTKAYASRTLLFLQDDRTLKPLAIELSLPHPDGDQFGTVSKVYTPADQGVEGSIWQFAKAYVAVNDMGIHQLISHWLNTHAVIEPFVVATNRHLSVLHPIHKLLHPHFRNTMNINALARETLTYDGGFETSLFPAKYSMEMSAAAYKDWVFPEQALPADLLKRGVAVEDLSSPHGIRLLILDYPYAVDGLEIWAAIKSWVTEYCKFYYKSDETVEKDTELQAWWKELREEGHGDKKDEAWWPKLQTRQELRDCCTIIIWIASALHAALHFGLYSYAGYLPNRPTLSCNLMPEPGSVEYEELKTNPDKVFLKTFVPQLQSLLEISIFEVSSRHASDEVYLGQRDSIEWTKDKEPLVAFERFGKMLSDIENRIMIMNSHKSWKNRSGPVNVPYTLLFPTSEEGLTGKGIPNSVSI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
What are the official names of this protein?
Linoleate 9S-lipoxygenase B, Lipoxygenase B.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_NITMU
Sequence: MQWETVIGLEVHAQLSTESKIFSGASTAFGAAPNAEACAVDLALPGVLPVLNRGAVERAIRFGLAVGAKINSPSIFARKNYFYPDLPKGYQISQYELPVVEGGHIQLQVVQDGKEQEKTVRLVRAHLEEDAGKSLHEDFHGMSGIDLNRAGTPLLEIVSEPDMRSSAEAVAYAKTLHTLVRWIGICDGNMQEGSFRCDANVSVRPRGSDKLGTRCEIKNLNSFRFLEKAIDYEVRRQVEILEDGGSIQQQTRLFDPEKGETRAMRSKEDAQDYRYFPDPDLLPLEISGNWIEEVKKGLPELPQQIRTRFEHDYGLSMYDALLLTGDRDISEYYEAVVGKLPSDPKLCANWVMGEVSAYLNNEGKSFDVCPLSPAQLAQLLLRIKDGTISGKIAKDVFRQMWAQAGTESISWRNSEGVDEGLADRIIDSQGLRQISDSSALENLVHEVLAANPKSVEEFKAGKEKAFNALMGQVMKAARGKANPAQVNEILRKKLTE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: FUT8_PANTR
Sequence: MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK
What is the function of this protein?
Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
What are the official names of this protein?
Alpha-(1,6)-fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose--glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 23 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: HBSAG_HBVD4
Sequence: MGQNLSTSNPLGFFPDHQLDPAFRANTRNPDWDFNPNKDTWPDANKVGAGAFGLGFTPPHGGLLGWSPQAQGILQTLPANPPPAATNRQSGRQPTPLSPPLRDAHPQAMQWTSTTFHQALQDPRVRGLYFPAGGSSSGTVNPVPTTASPILSIFSKIGDLAPNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFAGLSPIVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWAYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.