PharMolix/UniProtQA huggingface dataset:
Protein: AK17A_HUMAN
Sequence: MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQNHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKIDFPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEKFGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR
What is the function of this protein?
Splice factor regulating alternative splice site selection for certain mRNA precursors.  Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
What are the official names of this protein?
A-kinase anchor protein 17A, AKAP-17A, 721P, B-lymphocyte antigen, Protein XE7, Protein kinase A-anchoring protein 17A, PRKA17A, Splicing factor, arginine/serine-rich 17A.
Protein: DEF4_RAT
Sequence: MRTLTLLITLLLLALHTQAESPQERAKAAPDQDMVMEDQDIFISFGGYKGTVLQDAVVKAGQACYCRIGACVSGERLTGACGLNGRIYRLCCR
What is the function of this protein?
Host-defense peptide that has antimicrobial activity against Gram-positive and Gram-negative bacteria and fungi (in vitro) (PubMed:2543629).  Exhibits activity against E. coli, A. calcoaceticus, S,aureus and C. albicans (PubMed:2543629).
What are the official names of this protein?
Defensin alpha 4, Neutrophil antibiotic peptide NP-4, RatNP-4, Neutrophil defensin 4.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LMX1B_HUMAN
Sequence: MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
What is the function of this protein?
Transcription factor involved in the regulation of podocyte-expressed genes (PubMed:24042019, PubMed:28059119).  Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
What are the official names of this protein?
LIM homeobox transcription factor 1-beta, LIM/homeobox protein 1.2, LMX-1.2, LIM/homeobox protein LMX1B.
What are the subcellular locations of this protein?
Nucleus.
Protein: BESD_STREN
Sequence: MCAPLEKDDIRRLSQAFHRFGIVTVTELIEPHTRKLVRAEADRLLDQYAERRDLRLATTDYTRRSMSVVPSETIAANSELVTGLYAHRELLAPLEAIAGERLHPCPKADEEFLITRQEQRGDTHGWHWGDFSFALIWVLQAPPIDVGGLLQCVPHTTWDKASPQINRYLVENPIDTYHFESGDVYFLRTDTTLHRTIPLREDTTRIILNMTWAGERDLSRKLAADDRWWDNAEVSAARAIKD
What is the function of this protein?
Involved in the biosynthesis of terminal alkyne-containing amino acids such as L-propargylglycine (Pra) and L-beta-ethynylserine, that are produced as antibiotics by S. cattleya.  Catalyzes the chlorination of L-lysine at the C4 position, leading to the production of 4-chloro-L-lysine.
What are the official names of this protein?
L-lysine 4-chlorinase, Halogenase BesD.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate/Fe-dependent halogenase family.
Protein: IHFA_COXBN
Sequence: MALTKADLSEHLFNVVGLNKREAKDLVELFFKEISLSLERGEPVKLSGFGNFNLRDKGERPGRNPKTGEEIPITARRVVTFRAGHKLKSRVEKNVKPKEEGES
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MDTK_YERP3
Sequence: MQKYIVEARSLLALAIPVVIAQLSQTAMGVVDTIMAGSVSATDMAAVAVGTSIWLPAILFGHGLLLALTPTVAQLNGSGRRSQIAHQVRQGFWLALCVSVLIMLVLYNSDHVIKQMDNIDPVLAQKAVGFLHAIMWGVPGYLFFQVLRNQCEGLSKTKPGMVIGFVGLLVNIPINYIFIYGKFGAPALGGVGCGVATASVYWVMFLMMRWYVTRARSQQDIKLEKGFAAPDWQVMKRLSGLGLPVALALFFEVTLFAVVALLVSPLGIVAVAGHQIALNFSSLMFMLPMSLSVAATIRVGFRLGQGSVEQAQVAAYTSMAVGLLLASVTAVFTIVFREHIALLYNKTPEVVTMASHLMLLAALYQLSDAVQVIGSGVLRGYKDTRSIFFITFTAYWLLGLPSGYLLGLTDYILPAMGPAGFWIGFIIGLTAAAILMVLRIRWLQKQPTAFILQRAAH
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPZ6B_ORYSJ
Sequence: MALRLAERLSLEEDSVGGGNLVFSPLSIYSALTVVTAGARGTTLAELLAALGAPSSRDALAEDAGEIVRALPGGSGTATGGPRVAHACGLWHDRRRNVKPAFRDAAAASFQATTRAVDFLANPEEARNEINSWVAAATENLIDTILPPGSVSTDTRLVVASAIYFNATWQTPFRKQDTKKDKFHILGGGGDVDADFMRSGDDQYVAAYDGFKVLKMPYNTRASRTHTQPQYSLCVFLPDKRNGLWTLADRMEAGGGEVFLREHMPEKRVKVGEFRIPRFKLSFDGSIKTALQGVGVRAVFDPAAADLSDVLEEGNSGDPPLFVSDVLHGAAIEVNEEGTEVAAATVVIMKGRARRPSPAPAPVDFVADHPFAFFVVEESSGAVLFAGHVVDPTNPSQL
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serpin-Z6B, OrysaZ6b.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: DNAA_HAEIN
Sequence: MNLSNLWQSCLLQLQDQVSASDLSTWLRPLQADVVADNHIVLYASNMFVKGWVETHYLAQIQQICQTLAQNPELRISLKEGVKPAPKIVESTPNTSLRSESAVDFQAESSASVKFESHLNTKHLFDNFVEGKSNQLARAVGQKLAQAPGEPSANPFFLYGGTGLGKTHLLHAIGNGILADKPNARVLYIHANNFMQHMVKAVRDNKMDQFKKFYRSLDALLVDDIQFFAEKEKTQEEFFHIFNSLFETGRQIILTSDRYPKEIEKIEERLKSRFGWGLTTAIEPPDLETRVAILLKKAEEHNMNLPEEVAFFIAQRLRTNVRELEGALNRVKAMQDFKGGDIDIDFVRDTLKDILALQERLVTIENIQKVVAEYYRIKVSDLKSKSRARSVTRPRQIAMALAKELTNRSLPEIGRAFDRDHTTVLNACREVPKFREQDNSIQEDWANLIRTLSA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C5AR1_ONCMY
Sequence: MDDMCSILTEEELSLYNITDCEFVKPGGLGPVLGPRHLSALVFYGLVFLLGVPGNALVVWVTGFRMPRSVTSLWFLNLALADLLCCLSLPLLMVPLAMDQHWPFGPVACKLLKGLLYLIMFCSVLLLVLISLDRFLLVSWPVWCQNWRRPRKAGWVCVGVWLLALLGSIPQFVYVKEVQLSTSKSECLGLYTVASAWANTTARFLVGFVLPFITIVTCHWVVYSRARRGSGVGPGRVSEARSRRTLRVIVAVSLSFFLCWFPLHILDFLVLSTPRHSSHSANIQLAHTLALCLAYCNSCLNPLLYVCLGRGFKQNINRSLRNMFNFATEESVTRQSMFKSTSERTQEMNM
What is the function of this protein?
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.  This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
What are the official names of this protein?
C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_FRAT1
Sequence: MIQMQTELQVADNSGAKRVECIKVLGGSHRRYASIGDVIKVTVKEASPRGKAKKGSVYNAVVVRTAKGVRRKDGSKVRFDGNAAVLLNANGQPIGTRIFGPVTRELRTEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CYB_MOGWO
Sequence: MTNIRKTHPLMKIVNNSFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDTDKIPFHPYYTIKDILGALILILALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILALMPFLHTSKQRSMMFRPISQCLFWLLVADLFTLTWIGGQPVEHPFIIIGQLASILYFSLILIMMPLASLVENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLPD_STAAR
Sequence: MALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVNVIDKLTNENYTIKAKKVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQTSQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDSIIDIMADMLDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE
What are the official names of this protein?
Aerobic glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOP_DANRE
Sequence: MSANGNAALGVRLTEDQVKVLEENFTKVSKHPDETTLMLIAAECGLSEEQTAVWFRMRNAQWRKAEGLPAELGSVKD
What is the function of this protein?
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development.  May act via an interaction with SRF, leading to modulate the expression of SRF-dependent cardiac-specific genes and cardiac development (PubMed:12297045).  May act as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assist in chaperone-mediated protein refolding (By similarity).
What are the official names of this protein?
Homeodomain-only protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y230_SYNY3
Sequence: MCQNLGKFEIVVSHYRRVKAMNVIVDLCVVPLGVGVSVGQYVAACQKVLAEAGLKHTMHAYGTNIEGDWDEVFAAVKACHEAVHALGAPRITSSMRFGTRTDRPQTMDEKVKSVETWLENS
What are the official names of this protein?
UPF0045 protein sll0230.
What is the protein family that this protein belongs to?
Belongs to the UPF0045 family.
Protein: PETN_DRIGR
Sequence: MDIVSLAWAVLMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: HBA2_ARCGL
Sequence: MSLSSKDKATVKLFWGRMSGKAELIGADALSRMLAVYPQTKIYFSHWKSLSPGSSEVKKHGKTIMMGIGDAVTKMEDLERGLLTLSELHAFKLRVDPTNFKLLSLNILVVMAIMFPEDFTPMAHLAVDKFLCALALALSEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL20_PASMU
Sequence: MARVKRGVIARARHKKVLKAAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKSAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: KATG_PROA2
Sequence: MSEQSRCPVTGRTADSPATGSGLSNRDWWPNQLHLDMLHQHSSLVNPMGEGFRYKEEFGKLDLKEVKKDLYALMTDSQEWWPADYGHYGGLFIRMAWHSAGTYRTSDGRGGGGTGNQRFAPLNSWPDNANLDKARRLLWPIKQKYGKKISWADLMILAGNCALESMGFKTFGFGGGRVDIWEPEEDIYWGKEVEWLGNKRYSGERDLENPLAAVQMGLIYVNPEGPDGKPDPVAAGRDIRETFARMAMNDEETVALVAGGHTFGKCHGVGDPKLVGPEPEAADIEEQGLGWKSGYGIGKGDETMTSGLEGAWTPDPIHWDMGYLGMLFRYEWELTKSPAGAWQWKPKDVAEEDLAPAAHDPSKRVPTMMTTADLAMRMDPIYGPISQRYYEHPDQFADAFARAWFKLTHRDMGPHSRYLGAEVPAEELIWQDPVPALDHDLIDAEEIAELKKRLLASGLSIPELVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEVNQPEQLQRVLHKLEEIRNTFNGEQSGNKQVSLADMIVLGGCAAVEEAAGKAGTGVTVPFTPGRTDALQEQTDTESFSVLEPLADGFRNYMKKKYSVSAEEMLVDRSQLLTLTAPEMTVLLGGLRVLGANFQQSPHGVFTTQPETLTNDYFVNLLDMGTEWKPLSKEQDTFEGRDRKTGEPRWTATRVDLIFGSNSRLRAIAEVYGSDDAQEKFVHDFVAAWDKVMNLDRFDLG
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL22_ECOSE
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: BIOF_CITK8
Sequence: MTWQQKIDDALTARRSADALRRRYAVTQGAGRWLVANERQYLNFSSNDYLGLSHHPQIIRAWQQGAERFGVGSGGSGHVSGYSVAHQALEEALAGWLGYSRALLFISGFAANQAVIAALMAKDDRIVADRLSHASLLEAANLSPATLRRFTHNDPQHLARLLDAPCGGQQLVVTEGIFSMDGDGAPLAEIHRAARQRNAWLLVDDAHGIGVTGDEGRGSCWRQQVKPELLIVTFGKGFGVSGAAILCSESVADYLLQFARHLIYSTSMPPAQAQALSAALAVIRSPEGADRREKLAALIQRFRSGVKASDFTLANSHSAIQPLIVGDNARALRLADTLREQGCWVSAIRPPTVPAGTARLRLTLTQAHEAQDIDRLLEVLDGAG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: YEGI_ECOLI
Sequence: MKTNIKVFTSTGELTTLGRELGKGGEGAVYDIEEFVDSVAKIYHTPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDSDSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTENHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDITHFRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMFQQAFTESGVATGRPTAKAWVAALDSLRQQLKKCIVSAMHVYPAHLTDCPWCALDNQGVIYFIDLGEEVITTGGNFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYIILLEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKAYKAEVQQRREAFNRAKMDYDHLVRQIQQVGGLEGFIAKRTMLEKMKDEILGLPEEEKRALAALHDTARERQKQKFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWKASCERRFVFRPNEAITPADRQAVMAKMTAKRHRLESALTVGATELQRFRLHAPARTMPLMEPLRQAAEKLAQAQADLSRC
What is the function of this protein?
Probable serine/threonine kinase.
What are the official names of this protein?
Protein kinase YegI.
Protein: 3O1D_MYCTO
Sequence: MFYMTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVEKAPHYGGSTARSGGGVWIPNNEVLKRRGVRDTPEAARTYLHGIVGEIVEPERIDAYLDRGPEMLSFVLKHTPLKMCWVPGYSDYYPEAPGGRPGGRSIEPKPFNARKLGADMAGLEPAYGKVPLNVVVMQQDYVRLNQLKRHPRGVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVELNTAFTDLFVENGVVSGVYVRDSHEAESAEPQLIRARRGVILACGGFEHNEQMRIKYQRAPITTEWTVGASANTGDGILAAEKLGAALDLMDDAWWGPTVPLVGKPWFALSERNSPGSIIVNMSGKRFMNESMPYVEACHHMYGGEHGQGPGPGENIPAWLVFDQRYRDRYIFAGLQPGQRIPSRWLDSGVIVQADTLAELAGKAGLPADELTATVQRFNAFARSGVDEDYHRGESAYDRYYGDPSNKPNPNLGEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAAGNVSAPVMGHTYPGPGGTIGPAMTFGYLAALHIADQAGKR
What is the function of this protein?
Involved in the degradation of cholesterol (PubMed:16000729).  Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids (By similarity).  Is also involved in the formation of 3-keto-1,4-diene-steroid from 3-keto-4-ene-steroid (By similarity).
What are the official names of this protein?
3-oxosteroid 1-dehydrogenase, 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase, KSDD, 3-oxo-Delta(4)-steroid 1-dehydrogenase, KSTD.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily.
Protein: YR261_MIMIV
Sequence: MGKIRLAVIGVSGRNKMDFNLLSKEMFDYMIDNVEAYIKYHLETSNDKIVLVSGGSAWADHSVVKLFLEKNFAGLELYLPTEFTNGKFKDSHQGSILNNLHKHFSEQIGENSLDQIFDCILDPNCKVSVHNGFFKRNTLIAEESDHVIAFTFDEKPKGGTLDTWNKIKHNNKLNINLSIYL
What are the official names of this protein?
Uncharacterized protein R261.
Protein: HEPC_MORCS
Sequence: MKTFSVAVAVAVVLAFICLQESSAVPVTEVQELEEPMSNEYQEMPVESWKMPYNNRHKRHSSPGGCRFCCNCCPNMSGCGVCCRF
What is the function of this protein?
Antimicrobial activity against Gram-negative bacteria such as E. coli.
What are the official names of this protein?
Hepcidin.
What is the protein family that this protein belongs to?
Belongs to the hepcidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CIPKO_ARATH
Sequence: MTKKMRRVGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAENVERNDEGPLMMNAFEMITLSQGLNLSALFDRRQDFVKRQTRFVSRREPSEIIANIEAVANSMGFKSHTRNFKTRLEGLSSIKAGQLAVVIEIYEVAPSLFMVDVRKAAGETLEYHKFYKKLCSKLENIIWRATEGIPKSEILRTITF
What is the function of this protein?
Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance.  Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1.  CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.  Phosphorylates CBL1, CBL4 and CBL10.
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 24, Protein SALT OVERLY SENSITIVE 2, SNF1-related kinase 3.11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Targeted to the cell membrane when interacting with CBL1 or CBL5 and to the tonoplast when interacting with CBL2 orCBL10.
Protein: ARLY_ACIB3
Sequence: MTTSSNPPNSAAPNQTSGMWGGRFSEATDAFVAEFTASVQFDQRFYKQDIAGSIAHATMLAKVGVLTEAERDDIIEGLSTIRAEIEAGTFEWRIDLEDVHMNIESRLTQRIGITGKKLHTGRSRNDQVATDIRLYLRDEIDDILGLLERLQKGLLGLAAKNVNTIMPGFTHLQTAQPVTFGHHLLAWFEMLVRDTERLQDCRKRVNRMPLGSAALAGTTYPIDRAYTAELLGFEAVSENSLDAVSDRDFAIEFNAAASLIMMHLSRMSEELILWTSAQFKFVNIPDRFCTGSSIMPQKKNPDVPELIRGKSGRVFGDLVSLLTLMKGQPLAYNKDNQEDKEPLFDAIDTVRGSLMAFADMIPALVPNVEIMREAALRGFSTATDLADYLVKKGVAFRDAHEIVGKAVALGVAEEKDLSELTLEQLQQFSDLITADVFDKALTLEASVNARDHIGGTSPKQVEAAIARAHKRLEQLYA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3G_VANPO
Sequence: MTEAMNSEVINNPDGTKTIITYRVENGQKFKITQKVREVHVSEKVHKAVASRKQWAKYGEERNAPPGPNHSTTQLGEEVYLRLSRNWKQKEEEETEKAKIKSDGIISCRLCGNAHYTMNCPFKSIMSDIAALEDPNAPIEVGSNAVEAPVETASSAAAVASGKYVPPSRRAGAKDPSSDAYRDSRERDDMATLKITQLNENADETTLREELLFPFGNIPRVVVVRNRETGRSRGLAFVTFSSEEVAEKARRLLNGRGFMNLILQVDWSKPKEKE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_ALKOO
Sequence: MIEIIVPATTANIGPGFDCLGMALNLYNKVLFEEIEDGLQIHGCEERFNNKENLVYTSMIHTFKKVGYTPSTGFKITMDCHIPESRGLGSSAACILAGVIGATELSNSKLNKEEILKIATEIEGHPDNITPALFGGMTVSIQDQTSIHFSKVPIQNNFRIYGLIPNFTLSTKESRAVLPQEVSFQDAVFNVGRTALMLASFMNGDLELLNFSIDDKLHQNYRASLIPEYPSIIEKLNFLDIKGSFLSGAGPAIIVIAGKDNLGLADRIQNRMLELENKWTVKEFNMDTQGALIKRWR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_FRATH
Sequence: MKKFFIIGTNTEVGKTYISTKLIEVCEHQNIKSLCLKPVASGQSQFSELCEDVESILNAYKHKFTAAEINLISFNQAVAPHIIAAKTKVDISIENLKQFIEDKYNQDLDILFIEGAGGLLTPYSDHTTQLDLIKALQIPVLLVSAIKVGCINHTLLTINELNRHNIKLAGWIANCNDSNIKYIDEQINTIEELSGYKCSAKISRNADYLDFIDLSKILI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_BUCBP
Sequence: MAKTIQAYIKLQVSAGTANPSPPIGPALGQKGINIMEFCKAFNTRTNNLEKGLPIPTIITVYSDKSFSFITKTPPASVLLKKAAGITKGSSKPNQNKVGTITMQQILDIAQIKKIDMTGSNIDNISKSIIGTANSIGLIIAEGTNK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.