PharMolix/UniProtQA huggingface dataset:
Protein: CBIN_HALS3
Sequence: MNRWLAAGGILLGALVVFSFVSAGAWGGADGVAGDTITTINPSYEPWFQSLWTPPSGEIESLLFSIQAAVGGIIIGYYLGRDRPRGQSQDMGSDLP
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAMD1_MOUSE
Sequence: MDDWKSRLVIENMLPHFNMVGNRQETRKLQESGTSKRRQEGENFHFTGMADGSYPNKIKRPCLEDVTLSMGPGAHPTSLSTEMQMPTLNMNPTSADLGVAGQSLLLENNPLDSNVVNSSAMGSPFGVPSTADTGLKGHAVPYYEKNNSMPAVDQELQDLLEELTKIQEPSSNDLDLEKILGSKPEEPLVLHNPQAPLGPPAKLPVQMPHMESLGSSKEFASSCSQVAGTSLPIMPSSTGMSYSIPSSSKQIVSSSSSTAQAQVKNQVQNMLPVTMPPLSVPQWHHAHQLKALAASKQGSATKQGSNRNWSSLPPPGLSPPYLPVPSPHPPPPQPPPPPFSPQNFTASCMSSSSLSGSAVQSSPNALLSSMAPSSNASLGPTLPYVPAKLPGLPLNQQPQFSPQSSILANLVSSSVKSPQGHLISALPTSTPGPSPPYRPENLSSPGLPQQSFTPQYSLIRSLTPTSNLLSQQQQQQQQQQQQQQQQQQQQQQQQHQANSIFKPMTSSQQPKTLSMIMQQGLSSSSPEAPEPFTFSNTKPLSHFVSEPSPQKMASMSTHSRQSSLLHYLPQATPAHAPSATASSTATATLQLQHHHQQHHHQQHHHQQQHHQQQHHQQHHHQQQQHQQQQHQQQQQQQPDQSSFLLQQIMQQPQRFQRMMASDSMPALPGQGCCHRCAWTSTALWLEHQHQQWNSLTSTHGHVPPSNLTHVDKACKLGEARPPHVSLGRQPPSRQALGSESFLPGSSFAHELARVTSTSSYNTSEAAPWGGWDPKAWRQVPAPLLPSCDAAAREAEIRSYGNDP
What is the function of this protein?
Transactivates the HES3 promoter independently of NOTCH proteins.  HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ (By similarity).  Required for testosterone production.
What are the official names of this protein?
Mastermind-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the mastermind family.
What are the subcellular locations of this protein?
Nucleus. Note=Punctate nuclear localization.
Protein: YCF3_SORBI
Sequence: MPRSRINGNFIDKTSSIVANILLQIIPTTSGEKRAFTYYRDGAIMLAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSD_VIBCM
Sequence: MDKIKVGLQYWIPQHALTRLVGKLASARAGSLTTAIIRWFIKQYNVNMDEALHSDPTHFKTFNEFFVRELKAGVRPIAEGEKVITHPADACVSQFGAIEYGKLIQAKGHTYSAQELLGGDAKLAEEFRDGDFATLYLSPRDYHRVHMPCDGTLRQMIYVPGDLFSVNPLTAENVPNLFARNERVVCIFDTEFGPMAQVLVGATIVGSIELVWAGTVTPPRGNTVYRWDYPANGNQAVVLKKGEEMGRFKLGSTVINLFAKQAIRFDDSMALGAPTRMGEPYAHQA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPMI_ANAMM
Sequence: MSGSAVVLCILDGWGNGNGDECDAIHAARKPFWESVVSGCPRSSLSASGEDVGLPAAQVGNSEVGHISLGAGRVVLQDLQRINAEIGEIHSNPYLLQFAEAIKNGRGVCHIMGLLSDGGVHGLQDHITQLARVLAELRIKVLIHAFLDGRDVSPRSAKKHVTALNDAVHSYDISIATISGRYYAMDRDHRLDRTEKAYEAIALARGPRYRDAMTAIESSYSEGISDEFLVPSVIGDYQGFSPKDGILLTNFRSDRIVQILSMILHRSQEVSNILGMVRYSEKIQVPSLFPPRNICNTLGEVVSKCGLKQLRIAETEKYAHVTFFFSGGKEEPFPGEDRVIIPSPQVSTYDLQPEMSAFPMTEVLVERIESRQYSLIVVNYANADMVGHTGNLEAVKKAISVIDACLQMVFNAAKKAGATMLITADHGNAEKMFDMRGTPFTAHTSNTVPLVLCNCDKRFGLVDGRLCDVAPTILELMEIAKPDEMTGSSLLTPE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: ENGB_PORGI
Sequence: MEIKKAAFVISNTDVRKCPDTRLPEYAFIGRSNVGKSSLINMLTGQKGLAMTSQKPGKTQLINHFIIDDSWYLVDLPGYGYARLGASNRESLRRIIETYILCREQLSSLFVLIDCRHEPQKIDLEFLQWLGENGIPFSIVFTKADKLSFSRLKENTEAYKQKLLETWEELPPVFITSSEKKTGKEELLDYIDSINQELATK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NUOA_PARPJ
Sequence: MNLAAYFPVLLFLVVGTGLGVALVSIGKILGPNKPDTEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFLAMMIFLLEFLLGFAYIWKKGGLDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BDHA_BACSU
Sequence: MKAARWHNQKDIRIEHIEEPKTEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVDKPHPLTNETAPVTMGHEFSGEVVEVGEGVENYKVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAGGGGGFSEYVSVDEELLFKLPDELSYEQGALVEPSAVALYAVRSSKLKAGDKAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQQKAEELGAIIVDPSKTDDVVAEIAERTGGGVDVAFEVTGVPVVLRQAIQSTTIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPAVLSLMKEGYFSADKLVTKKIVLDDLIEEGFGALIKEKSQVKILVRPN
What are the official names of this protein?
(R,R)-butanediol dehydrogenase, Acetoin reductase/2,3-butanediol dehydrogenase, AR/BDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RL11_LYSSC
Sequence: MAKKVIKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVEISVFEDRSFTFITKTPPAAVLLKVAAGIQSGSGEPNRKKVATVKRDKVREIAETKMPDLNAASVEAAMLMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CHLB_ISOEC
Sequence: KRLLADLGIQINEVIPEGGSVNQLKNLPKAWVNLVPYREVGLMTAIYLEKEFGMPYISTTPMGIVDTAEWIHQIEFYINKLAPNILGYKVNYESYIDQQSRFV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex (By similarity).
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL16_CAUVC
Sequence: MLSPKKTKFRKQFKGRIHGTSKGGTLLNFGSYGLKAVEPERITARQIEAARRAITRQMKRQGRVWIRIFPDVPVTGKPAEVRMGKGKGAVDYWAARVAPGRIMFEIDGVPDDIAREALRLGAAKLPIRTRVVTRIDAGVAQEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DTD_HAEIG
Sequence: MIALIQRVSQAKVNVKGETIGKIGKGLLVLLGVEKEDNREKADKLAEKVLNYRIFSDENDKMNLNVQQAQGELLIVSQFTLAADTQKGLRPSFSKGAPPALANELYEYFIQKCAEKLPVSTGQFAADMQVSLTNDGPVTFWLNV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_GEOMG
Sequence: MITGIKGFNDILPGEVERWQHIEATARRVFGLYGYAEIRVPILEKTELFCRSIGDTTDIVEKEMYSFVDKGENAVTMRPEGTASVMRAYIEHKLYAQDPVAKLYYMGPMFRYERPQKGRYRQFHQIGAEVTGVTDPKVDAQVLTMLCHFFAELGLTEPTLQINSLGCPECRPVYREALKSFLRERLDRLCDDCKRRYETNPLRALDCKSAHCKEATADAPAMLDHLCAGCDDHFAATRRHLERAGTPYSINNRMVRGLDYYTRTTFELVTGLLGAQSAVAAGGRYDGLIADLDGPAVPGIGFAMGVERVALLLGQQEFARRPDLFIAALGTEAQDEAFRLMCGLQRLGVSVEMDYEGKSLKSQMRRSDKFNSRFTLIIGSDEMASGRATLKAMDTGTQSDVLLDPTAIAGQVK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX2_BUTOC
Sequence: GRDAYIAQPENCVYECAKNSYCNDLCTKNGAKSGYCQWLGRWGNACYCIDLPDKVPIRIEGKCHF
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin Bot2, Bot II, BotII, Neurotoxin II.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DJC24_HUMAN
Sequence: MMAVEQMPKKDWYSILGADPSANISDLKQKYQKLILMYHPDKQSTDVPAGTVEECVQKFIEIDQAWKILGNEETKREYDLQRCEDDLRNVGPVDAQVYLEEMSWNEGDHSFYLSCRCGGKYSVSKDEAEEVSLISCDTCSLIIELLHYN
What is the function of this protein?
Stimulates the ATPase activity of several Hsp70-type chaperones.  This ability is enhanced by iron-binding.  The iron-bound form is redox-active and can function as electron carrier.  Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
What are the official names of this protein?
DnaJ homolog subfamily C member 24, CSL-type zinc finger-containing protein 3, Diphthamide biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the DPH4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ASPD_CUPTR
Sequence: MLHVSMVGCGAIGRGVLELLKSDPDVVFDVVIVPEHTMDEARGAVSALAPRARVATHLDDQRPDLLVECAGHHALEEHIVPALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLLSGAIGAIDALAAARVGGLDEVIYTGRKPARAWTGTPAEQLFDLEALTEATVIFEGTARDAARLYPKNANVAATVSLAGLGLDRTAVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLAANPKTSALTVFSVVRALGNRAHAVSI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: D2_ONCVO
Sequence: WDAEPGALYTLVMTDPDVPSRKNPVFREWHHWLIINISGQNVSSGTVLSDYIGSGPPKGTGLHRYVFLVYKQPGSITDTQHGGNRRNFKVMDFANKHHLGNPVAGNFFQAKHED
What are the official names of this protein?
Protein D2.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
Protein: FAR2_CALVO
Sequence: TPSQDFMRF
What is the function of this protein?
Able to induce fluid secretion from the isolated salivary gland of Calliphora.
What are the official names of this protein?
CalliFMRFamide-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_GEOSW
Sequence: MTNPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHKFYLIDTGGIDIGDEPLLVQIRQQAEIAIDEADVIIFMVNGRDGVTAADEEVAKILHRSNKPVVLAVNKIDNPEMRDLIYDFYALGFGDPYPISGSHGTGLGDLLDAVARHFPKRGQEEYEEDVIKFCLIGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTTFVREGQEYVIIDTAGMRKRGKIYESTEKYSVLRALKAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVIIVVNKWDAIEKDDKTLIEFERKIRDHFPFLDYAPIIFVSAKTKQRLHKLLPLVRMVSENHAMRVQTNVLNEVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIIARPRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: BAGP1_ARATH
Sequence: MVQSAVEVLLPSAWEIEVAVVASVFLIASYWLFAYRGGGDDDVVGVGFDRSRLMQNLDSGDAFDKDKIGHLRGDTQTNAAYIVKVELLAAKNLIGANLNGTSDPYAIVNCGSEKRFSSMVPGSRNPMWGEEFNFPTDELPAKINVTIHDWDIIWKSTVLGSVTINVEREGQTGPVWHSLDSPSGQVCLNINAIKLPVNAPRAVTGYAGAGRRRVTLDQQGPTIVHQKPGPLQTIFDLLPDEVVEHSYSCALERSFLYHGRMYVSAWHICFHSNVFSKQMKVVVPLGDIDEIRRSQHALINPAITIILRMGAGGHGVPPLGTPDGRVRYKFASFWNRNHTLKALQRAVNNYHAMLEVEKKERAQSALRAHSSSVKGGGKVQVKAPEDTAAVPVKFQAFIKEEVLVNIYNDVFASTPEQVLNVLLADDSTYTNEYRSARKDKNLNIEPWHTAEEYDGQVREIKFRSICNSPMCPPDTAVTEWQHVVLSPDKKVLVFETVQQPHDVPFGSYFEVHCRWRLEAKDETSSVIDIRVGVHFKKWCLMQSKIKAGAIDEYKKEVEVMLEVALSYLKSHSSSSSHGDIDKSALSSPTPENIS
What is the function of this protein?
Involved in proteolytic processing of BAG6.
What are the official names of this protein?
BAG-associated GRAM protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RK12_CHAVU
Sequence: MEEKEQVDLNQLLNAIKSLTLQEIKIFTDKLQDELGISSDNLYSSRGILTESTSHNKEVEEIDEKTEFDIILEEVPSSSRITVIKVIRSITNSGLKEAKEFIEALPKTVKEGISKEEAESVKAQLEESGAKVTLR
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THI12_YEAST
Sequence: MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDMAILEPTNPSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITEDFQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGIECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVRKFLKAIKKATDYVLADPVKAWKEYIDFKPRLNNDLSYKQYQRCYAYFSSSLYNVHRDWKKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFKRLALPA
What is the function of this protein?
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway.  Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP).  The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
What are the official names of this protein?
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12, HMP-P synthase, Hydroxymethylpyrimidine phosphate synthase, Thiamine biosynthesis protein 12, Thiamine pyrimidine synthase.
What is the protein family that this protein belongs to?
Belongs to the NMT1/THI5 family.
Protein: COXZ_BRUMB
Sequence: MTDQGENEKKQRRSNATIAVACLSFFVCMIGAAYASVPLYRIFCQVTGYGGTTQRVEQYSDTILDKTIKVRFDANIANGLPWDFKPMQREVTVRIGETTMIKYEAHNLFGEETYGRASFNVAPGRAGAYFNKVECFCFTDNTLKPGEDLELPVVFFVDPEFVNDPDLKDVKTITLSYTFFPIDKPKPVVNAKAVGSTRNGG
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: AZOR_PSEA6
Sequence: MKNVLVLNASLQGENGNSSQLTSEFVTQLQQTESIKVEKVDLNTLNLPHLSAQEMQTWSMLSDNMTNDQAALAAYSNELLAQLERSDVIVVGMPMYNFTIPSTFKAWIDRVARAGRTFSYTSEGPKGHLQGKTVYIFAARGGIYQGTDNDTQTPYLKLVFGLMGITDVNFIYLEGLNMGEEYAQTSWQQARESLTTLLPATV
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: 2ABA_DROME
Sequence: MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFDRNSKKDVTLEASRDIIKPKTVLKPRKVCTGGKRKKDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF
What is the function of this protein?
Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment.
What are the official names of this protein?
Protein phosphatase PP2A 55 kDa regulatory subunit, PR55, Protein phosphatase PP2A regulatory subunit B, Protein twins.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
Protein: HIS4_POLNS
Sequence: MLLIPAIDLKDGHCVRLEQGDMDKATVFSEDPGAMAAHWISKGARCLHLVDLNGAFAGKLKNESAIKSILKAVGDEIPVQLGGGIRDLETIERLLDDGISTVIIGTAAVKNPGFVQDACTAFPGHVMVGLDARDGKVATDGWSKITCHKVIDLAKKFEDWGVEAIIYTDIGRDGMLKGVNIDATVKLAQAIRIPVIASGGLSNNQDIDALCKAEEEGVMGVIAGRSIYASDLDLAAAQKYADELTLKYKKKTN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOY_THEMA
Sequence: MRQLIKAGIFTALIVVGAWISIPLGPVPFTLQVFFVFLSAYVLGKKYGTLAVATYVLLGAMGLPVFANFKGGAQVLVGPTGGYLFGFILGAFVIGLLAEKKESFAWYLASGVAGLGIIYALGVFVLNFYVHDIRKAISVGFVPFVWFDLIKLVVAALIALRLKKLEVER
What is the function of this protein?
Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex.  Probably a biotin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (Probable).
What are the official names of this protein?
Biotin transporter BioY, Biotin ECF transporter S component BioY.
What is the protein family that this protein belongs to?
Belongs to the BioY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GDF8_HORSE
Sequence: MQKLQISVYIYLFVLILAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDLLMQVEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGAGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPRPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_LACH4
Sequence: MSIMQASCIALVSSLTLTVIFLPLLIKFMHSHHEGQEIRDEGPKWHQKKSGTPTMGGTIFVIAAVISVIWVTAWQHSLNKVVWILVISLLGYGIIGFLDDGIKLYYKRNLGLRAWQKLALQIIIAVVIVLIASSDHFNFGLYIPFAGVVHSVALFVIFIIFWLVGFSNAVNLSDGLDGLATGLSVVAYGTYAYIAFKQKNFAILAFCMSVIGGLIAFFIFNHKPAKIFMGDAGSLALGGGLATVSIMLNRPWSLLLVGIVFVCETASVIMQVISFQTTGKRIFKMTPIHHHFEMLGWSEWKVDIVFWIVGLVGSILYLAIWG
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDC_ERWT9
Sequence: MDSQRNLFLIAFLFVSFMIWQAWQTDNAPQPLQTQTTQNTTSAAGDAVNQGVPASGQGKTITVKTDVLSLNINTRGGDIDQAQLLTYPDKLGSDQPFLLLESTPGFLYQAQSGLTGRNGPDNPANGARPLYTSGQDHFELANGQGELRIPLTFTAENGVTYTKTFVLKRGEYAIGVDYQINNTTQQPLEVSMFGQLKQTIDLPKHRDTGSSNFALHTFRGAAYSSSETNYEKYKFDTIRDNENLSTTTNNGWVAMLQQYFATAWVPQTAGSNTLYTSNLGNGVAAIGYKSAPVIVAAGSQQQLAATLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKFLHGFIGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRMSQEMMALYKAEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLAAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSRDKKKA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSH_STAA2
Sequence: MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.