PharMolix/UniProtQA huggingface dataset:
Protein: DGCP_PSEAE
Sequence: MSRDDVQRWKDKYLENIEQQERLQRRWDARIDLLRRGLVRSSLAAEGSDKAVDQCMKELREILRRDDMDAGLSGLIPRLEKAVLDSEQRRQQRTQQNIDALGELAQQLLALDLPRELRKPLKQFARDIEERARQSREIPILLSELSRLQRQALAERKGGDAEDGRPSLLQRLFGGKESETTAEPSASVPSVVAASNTPIQPAAAAPSLPVAEHDEAPGGPPQPLPARTVAAIESAPAGWVGVAERGEPNQILLDEPREIWLDSLPLPAGLSFSETLEEAGAEPSPAMPADVESAPEAPATPVDNLDGQAVDEAYELPPPIPEPGYSAVAPHIEASLLRLLDGLSLPSSHQPQAEALRERIDGSLNWYELVPVLDDLAVLVLSLADSGQRDFEEYLRQLNERLESFLGHLGDAHAGYTDVLDNARGFDQSLREQVSGLQASVQQATDLNSLKLAVDSRLNGLLASMDEHQREQAEHEQEVSGRLQALMERVNSMEQDAKAFHSHLEDQRQKALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITCSAGITAFEGNEAGEAVFERADQALYRAKRAGRDRLEVA
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (PubMed:25809128).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (PubMed:25118352).  Localizes at the cell poles through interaction with FimV where it increases the local pools of c-di-GMP (By similarity).
What are the official names of this protein?
Diguanylate cyclase DgcP.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Localizes at the cell poles in a FimV-dependent manner.
Protein: DESI2_XENLA
Sequence: MANQPIILNVYDMYWINEYTSSLGIGVFHSGIQVYGREFAYGGHPYPFSGVFEISPGDSTELGDTFKFKEAIALGSTDFTENDIEKIIEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWVNRLAYFSTCVPFLQSCLPKEWLTPAALQSSISQELQDELEEAEDAAASASTSTTAMPRPGRHTKL
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Deubiquitinase DESI2, Desumoylating isopeptidase 2, DeSI-2, PPPDE peptidase domain-containing protein 1, Protein FAM152A.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_STAA2
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RUVB2_SCHPO
Sequence: MSISVTSHNDVSKLERIGAHSHIKGIGLNDNLEPKESSQGMVGQVKARRAAGVILKMIQEGRIAGRAILMAGPPSTGKTAIAMGMAQSLGSDTPFVTLSASEVYSLEMSKTEALLQALRKSIGVRIKEETEIIEGEVVEVQIDRSITGGNKQGKLTIRSTDMETVYDLGTKMIDSLTKEKVLAGDVISIDKSVGRVTKLGRSFSRARDYDAMGADTRFVQCPQGEIQKRKEVVHTVSLHDIDVINSRTQGFLALFSGDTGEIKPEVREQINTKVSEWREEGKAEIVPGVLFVDEVHMLDIECFSFFNRALEDDLAPIVIMASNRGITRIRGTNYRSPHGIPVDLLDRMLIISTLPYSHEEVKEILKIRCQEEDVDMEPSALDYLSTIGQETSLRYALLLISSSNQVALKRKSATIEESDIRRVYELFLDQKRSVEYLEEYGKNYITENEWSASGAQDNAVAMQED
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 2.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUS22_XENTR
Sequence: MGNGMNKILPSLFIGNFKDARDVEQLHKNNITHILSIHDSARPMLEGMKYLCIPASDSPSQNLIQHFKDSIAFIHECRLKGEGCLVHCLAGVSRSVTLVVAYVMTVTDFGWEDALSAVRGARTCANPNMGFQKQLEDFGKHDVYQFRTWLKETYGENPFNDKDDAKQLLDKHKQQEAAESQSATSSGRQWSSHLTSLSSMSYSNYTTET
What is the function of this protein?
Activates the Jnk signaling pathway.  Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase 22.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LIPB_GLUDA
Sequence: MHDRRAMTEKTILWNSSPGLVPYPDAIAGMEHQVAGIRDGSAPERVWLLEHPPTFTAGTSARDEDLFNPHHFPTYAAGRGGQWTYHGPGQRVAYVMLDLTAPHGVVPARDLRAYVHTLEEWLIRTLRRFDVTGERRADRIGVWVVDARTGAENKIAALGVRVSRWTCWHGVALNVAPNLDDFGGIVPCGIREHGVTSLHALGHKVSLGDVDEALRATWQDLFGSVPTPIGTA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1681_METJA
Sequence: MEKELKVITIDELKKYIRNNEEDKIEEVDVVTSATCGIMSGTAGIFHIPFNEVFKRAEEIYLNDIKGVVGICPNEFLGKVDAIFYGEVGFLFKDLVKGKVVEAKAISEGKIYKNEITIDDLPTAKMIGTRMAFKNYTAITNLSDEEVNTIFHRLPLKKGEASFSGCGMLNPLENMVIKDEKDVVGKKALLNGAEAIILGFGTRASIEKPNLMMSADMKDMDAYYLGGFVTSNGIEIYNTIAVPIKVDEHKEALKKLDKDITLPLVNIFGREIIDIGSYAEVWENVDLRPKIYQDKCKNCRECLVEKYCPTFAIKRENGKIKITEDCFGCGVCNICPYGVFKTKLGSVCGIPITCRQSDRKRALKLAKELKKKIERGEFKI
What are the official names of this protein?
Uncharacterized protein MJ1681.
Protein: YPSI_RHILP
Sequence: MGWRNGKLTPQSGVHYVAEGLPFNWTKVNTEGRKTFSAFAELEAAKEKVAILAVRADPAFGNLWHQLNAEVVDRCRRRNPLCMQTLFQRLLSAKSCTFIA
What are the official names of this protein?
Uncharacterized 11.3 kDa protein in psiA-psiB intergenic region, ORF-P.
Protein: PYRD_BURCH
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRALGAAGRTGLACALSARVPDAPRTVMGLTFRNPVGLAAGLDKDGAAIDGLAALGFGFIEVGTVTPRPQPGNPRPRMFRLPQAEALINRMGFNNHGVDQFVKNVQAARYRGILGLNIGKNADTPIERAAEDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQQRLADLHGKLVPLALKIAPDLDDEQVKEIGDTLLRHKIEAVIATNTTLSRAAVQGLPHADEAGGLSGRPVFDASNEVIRKLHAEVGNDVPIIGVGGIFSGEDAHAKLAAGAALVQLYTGFIYRGPALVSECVKAIARERSA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ACCA_SYNWW
Sequence: MVKRQFDYEQKVQEIREKLEELNNLSSNMEFDLSQEIESLEEKIENNRERRYKNLSPWEKVLLSRHPERPNSNDYIRYFCEEWIELHGDRHFGDDSSVIGGIGRFNGQAVTILGYRKGKDTRENLQYNFGMPHPEGYRKIQRLLLQAEKFQRPVITLIDTPGAYPGIGAEERGQAWAISQVLMTLSALEVPVIAVVSGEGGSGGALALAVADRLLMLSNAVFSVASPEACASILWKELERVEDMARAMKITANDLQRLGIVDEIIEEPLGGAHLNFPEMAEKLKKALQKHLGEILSQDSGELLEERFQKLRKIGEFRG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_STRM5
Sequence: MALLPILEFPDPRLRTKAALIDAAEVTTPAFQELVDNMFQTMYDAPGIGLAATQVDVHKRFMVIDVSEEKNEPHVFINPEIVAKDGGRVYQEGCLSVPGIFADVTRADTITVKYLDRDGQQQELEAGEVLATCIQHEMDHLDGKLFIDYLSPLKREMVRKKLAKQRKHVA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y1645_STRA5
Sequence: MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKQGEPDPESNSALKFVLDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADTVFEQLLEADVDVDDVEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKLIDALESDDDVQKVYHNVADF
What are the official names of this protein?
Probable transcriptional regulatory protein SAG1645.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_XYLFA
Sequence: MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGGMVGKEDGLAGATARQARLAAAEADVVLFVVNVREGVSALDDDILAWLRKLSQPTLLVINKIDGVSDATVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVLAWLPERGIGEALDEDSERIHIAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDECRYRLVDTAGLRRKSKVEEAVEKFSAFKTLQVIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWDGLGTYQREQAEDLLSRKLGFVNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEVNKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHGTRLKVLPDTYKRYLENFFRKRFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: D1A_HADVE
Sequence: CAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC
What is the function of this protein?
Inhibits tetrodotoxin-sensitive voltage-gated sodium channels (Nav) by binding to site 3.  Slows the inactivation, and causes a prolongation of action potential duration resulting in repetitive firing in autonomic and motor nerve fibers.  Does not depolarize the resting potential.  Does not affect tetrodotoxin-resistant sodium channels.  This lethal neurotoxin is active on both insect and mammalian voltage-gated sodium channels.  Pan-neuronal expression in Drosophila is lethal but flies engineered to express the toxin only in pacemaker neurons have profound defects in circadian rhythm but a normal lifespan.
What are the official names of this protein?
Delta-hexatoxin-Hv1a, Delta-HXTX-Hv1a, Delta-atracotoxin-Hv1, Delta-ACTX-Hv1, Delta-atracotoxin-Hv1a, Delta-ACTX-Hv1a, Delta-hexatoxin-Hv1a_2, Delta-HXTX-Hv1a_2, Versutoxin, VTX.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 06 (delta-actx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC2_PIPCE
Sequence: MEVLMAEQRADLVFHNKAIDGTAMKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVRDAEQQGLILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMHTNFRMTDPSNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISASPRNSMEEKIWIQRLIGHVLAYDIYIGPRCIAARNQDIGIGLVNRFITFQAKSIYIRTPFICRSTSWICRLCYGRSPTHGDLVELGEAVGVIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEYVRAPSNGKIKFHEDLVHPTRTRHGHPAFLCYIDLYVTIESRDILHKVNIPPKSFILVQNNQYVESEQVIAEIRAGTSALSFKEKVRKHIYSDSEGEMHWSTNVYHTPQYTYGNVHLLPKTSHLWILSGNPCKSNGALFSLHKDQDQMNLYSLSLSLEQRSISDFSVTNDRVRRKSFSLDPSREGRGGRFFDYSVPDKSIPNDCWNFIYSAILHENSYFLAKRRRNRFIIPFQYSQEGEKEPMPCSGISIEIPKTGILRRNTILAYFDDPRYRRSGSGITKYGTVEVDSLVKKEDLVEYRGEKELRTKYQTKVDRFFFIPEEVHILPGSSSIMVRNNSIIGVDTEIALNTRSRVGGLVRVERKKKRTELKIFSGNIHFPGETDKISRHSGILLPPGMEKKNSKESKKWKNWIYVQRVTPIKKKYFVSVRPVVTYEIADGINLATLFPQDSLQERDNVQLRVVNYILYGNGKPIRGISHTSIQLVRTCLVLNWDQDNKKTSSIEEVFASFVEVRANDLIRDFIRVDLVKPRVLNTGKRNDTAGYGLNPDNGSDCPNRNPFYSKIKIQSFTQDNGTIHTSLNINKQLPPFLILSSSNCFQAGPLKVNGSKSDNGKKKSIKEDPAILIRNFFGPLGTIAKITNLDSRNYYLTDNQILLKKYLILDNFKNLFQDVLYYLIDEKGRILNPDPCSNIILNAFDLNWCFLHHNSCEKTFSIISLGQLFYENGSIYKYRSHIKSGQIVTVHGDSLVIRSAKLHLATPGATVHGHYGEIIYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRVEGWNENITKILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNAFSPGELIGLLRAERTGRALEETICYRAILLGLTRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGFVRRSRQHNNISLEKKRNNLVKGEIGNILFHHRELFSSCISKNKKKFS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PVDQ_PSEAE
Sequence: MGMRTVLTGLAGMLLGSMMPVQADMPRPTGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEKVALSGEQAFQVAEQRRQRFRLERGSNAIAVGSERSADGKGMLLANPHFPWNGAMRFYQMHLTIPGRLDVMGASLPGLPVVNIGFSRHLAWTHTVDTSSHFTLYRLALDPKDPRRYLVDGRSLPLEEKSVAIEVRGADGKLSRVEHKVYQSIYGPLVVWPGKLDWNRSEAYALRDANLENTRVLQQWYSINQASDVADLRRRVEALQGIPWVNTLAADEQGNALYMNQSVVPYLKPELIPACAIPQLVAEGLPALQGQDSRCAWSRDPAAAQAGITPAAQLPVLLRRDFVQNSNDSAWLTNPASPLQGFSPLVSQEKPIGPRARYALSRLQGKQPLEAKTLEEMVTANHVFSADQVLPDLLRLCRDNQGEKSLARACAALAQWDRGANLDSGSGFVYFQRFMQRFAELDGAWKEPFDAQRPLDTPQGIALDRPQVATQVRQALADAAAEVEKSGIPDGARWGDLQVSTRGQERIAIPGGDGHFGVYNAIQSVRKGDHLEVVGGTSYIQLVTFPEEGPKARGLLAFSQSSDPRSPHYRDQTELFSRQQWQTLPFSDRQIDADPQLQRLSIRE
What is the function of this protein?
Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid.  Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length).  Degrades 3-oxo-C12-HSL, one of the two main AHL signal molecules of P. aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum-sensing system.  Therefore, may enable P. aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential.  Also appears to be required for pyoverdin biosynthesis.
What are the official names of this protein?
Acyl-homoserine lactone acylase PvdQ, AHL acylase PvdQ, Acyl-HSL acylase PvdQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VRTN_MOUSE
Sequence: MTSRDQLVQQVLRDLQEAVESEGLEGLIGAALEAKQVLSSFTLPICQKGGPGAQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEATSLLLWGHTGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTNLSFATLEAIFDADVKATCFPTSFSNVWHLYALASILECNIYSIYPMRNIKIRPYFNRVIMPRCSTHVTSMLHIMWAGQPLTSHLFRHQYFAPVVGLEEVEADCTASLNPVPPNLGPLLPPAKTLELLNREPGLSYSHLCDRISITKSTFYRWRRQTQEHRQKVATRFSAKHFLQDSFHRGGFVPLQQFLQRFPEISRSTYYAWKHELLGSGANSALGPATPSREALAVPEVERPPGKKAAEEVGCSSLAAAMLSPPSMILMQRAKSFLEYCISLNKLVPYRCFKCRFPGISRSTYYNWRRKALRRTPSFKLSQAAFETAESLQPTDVGKETPFSLKREAGEEETGKAGSGAPLTSRGLISPKMPLSRWQRRLRRAARKQVLNGHLPFCRFRLRYPSLLPSTFWVWKSLSRRSPGMQIPSLSQRRQKPQGRQKPEGRQKPEEQQKPEGRQKPEGRQKPVEPQAMEADQNVPAMVVPPAETLPVATSPEDVPGGPSREGNIIQEAAMTQSQPHSGSLPSQTLAEAPGGSDGQVLVMDMLTTTRFKAQAKLFLQKRFQSKTFPSYKEFQALFPLTARSTYYMWKRALYEGLTLIDG
What are the official names of this protein?
Vertnin.
What is the protein family that this protein belongs to?
Belongs to the vertnin family.
Protein: AMPR_RHOCA
Sequence: MDRPDLPLNALRVFEVAMRQGSFTKAAIELRVTQAAVSHQVARLEDLLGTALFLRTSQGLIPTDEGRLLFPVLEHGFDAMSRVLDRLGGRRDIEVLKVGVNTTFAMCWLMPRLEAFRQAHPQIDLRISTNNNRVEILREGLDMAIRFGTGGWTGHDAIPLAEAPMAPLCAPGLASRLLHPSDLGQVTLLRSYRSAEWPGWFEAAGVPCPPVTGPVFDSSVALAELATSGAGVALLPISMFESYIAQGRLAQPFGVTVSVGRYYLAWPSDRPATSAMSTFSRWLTGQSAE
What is the function of this protein?
This protein is a positive regulator of gene expression of cephalosporinase (AmpC).
What are the official names of this protein?
HTH-type transcriptional activator AmpR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_PECCP
Sequence: MENLSVDLLYMAAALMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSRP_THEM4
Sequence: MKIIATNKKAFSDYIILETYEAGIELRGTEVKSLRESGANFKDSFCRIKNGEVFLLNLNIPQYRNGSLNNHDPERPRRLLLHKKEIHRLLGKVKEQGLTIIPTKIYFNNRGLVKVEIAVAKGKKKYDKREDIKKREINRRIREYLKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HSP33_YEAST
Sequence: MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKVFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNGAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS
What is the function of this protein?
Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step.  May play a role in detoxifying endogenously produced glyoxals.  Involved in protection against reactive oxygen species (ROS) (By similarity).  Important for viability in stationary phase.  May negatively regulate TORC1 in response to nutrient limitation (PubMed:24706893).
What are the official names of this protein?
Probable glutathione-independent glyoxalase HSP33, Glyoxalase 3 homolog 3, Heat shock protein 33.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HSP31-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Present in processing bodies (P-bodies) and stress granule (SG) foci upon glucose starvation and heat shock.
Protein: TDA11_YEASL
Sequence: MNKFDEFIESNEKDLDVDTSTRNSIISMSPVRKTGRKIRSASSNGYRLEHHRTSSAGSMHSQRLMTPTRLNDQDHPLQAKPDARRVVTRHSSVSVPNAMSKRRSLIQPMVVPTTPESQNNLPSVSHSEGSYGIPLESTTVLSSEQAMASGLRRSRNGSSQSVNSMIATTIPTNGVDVSALLQSLATKELELLECKQKIEDLKKQTQHEEQNYTRRARELHELKEQVSKHLDPSLNTPVKNRAFSPVYQNIPLESRTENAGNSSLPSSVSKPKNMGHQSTNQSRSVSPQDIQERRQRDDSSDSSKQSLWSKPLALFNQFDKIIQHEIERTLNWDDSLSGTPEVQEGTPTSNSESSAQQYDNEAPGARQKSPSQGSVSRSLWSFVSDVKAGLLGIEEENDNDVITDNRCDPVYKSDRQHEQKKSTHKITNRGQAEDSGDDSSLNTRKFKTTTKFQKDNAGNNSLTDESGHRTREKKK
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRDI_BACCR
Sequence: MEEQLIPIQWKDDALVLLDQTLLPNEIVYESFKTAESVWDAIQVMKVRGAPAIGVSAAYGVYLGIKEFAESTEEGFMDEVRKVCTYLATSRPTAVNLFWALERMESVATDNIHLSISQLKNRLLEEAKEIHREDEEINRQIGEHALTLFHDGMGVLTHCNAGALATTKYGTATAPMYLAKEKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDRVAANGDVANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTSTGKEIPIEERDASEVINRFGKYSAPKESKVYNPAFDVTPHENVTAIITEKGIVKAPFTENLKKLFQ
What is the function of this protein?
Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
What are the official names of this protein?
5-deoxyribose 1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.
Protein: STU1_CRYNB
Sequence: MPKTLTESEVEATFAKLKAADPDRKVDIIQFFGLQLEDVEELPASVIDPFLLILPPLIRSPHSLLLSSVLSSFLPYFLPLIPKHPTTHLRLALLQVLPALLEKLNDAKERIHSAAGNAIVILGELSWEAEPPIPASNLNSSGSLKAGSLSSSTATKSKPHETLPHLWERHLKDVLQGKAWRSKVEGMKVLTKMRSKEGAKMGLKAWLGVLVDLLEDGDGNVRDQARETVVELLSPPSTPPAARSEFKRLLVARNVRKTIADDIITRILSGEGSDRSTPAVMNSELGKEEGASRSGAAAPAHSQADDVDIVYVASPQDLEREFHSMLPFFEGKETEENWAPRERSIVRIRGMMKGQAHVKYQAAFIAGLKGGIVLSLRTTVAQQSCYLLKELPEGLGAAFDNFVEFLLPILGKMSGFTKKLIADRSQTAVTSIITHTTVHPRIFINHISSGIQEKNVQIRAYSVNHLKTFLIVHASHAKHQIEATPGLSDTLDAAFRKALADVNPGVREVTRQAFWRYHEVWRSKAEVLMNSLDGQARKQLEKANPRTAASPMPSYASSSSTGAPSSANTKPPSKKMDLKAMLAERRRAVKEAGKQAQETNAGSPRVVSNPVFASPGVQHASITGLPRSSSAVGIARHVETSSPSPVRSPTPSSSATRIRPSPSPERIQSPIQTKIEIDSPLRSRYTSLTPDLARSPPKSPSPSLSPSLGLGESPLRQVLTYPAANGRHSVGEGKRAIPELVEVADNGAEHEVDELTLKEGQKTRDDGNTDQELPPTVQEEVDQVEQSQQFESEPRLEHPEPQQGNTFSTSTSGRVPSTPARSIATGTTASLPNSRNGNIKGEKIISSRLNPEAFQTPLNPKTSALRSSSAIRTPAWKDSPRPEAVTPQMMQKLKERRHERSWWVKRQELLEKASPLKPLTPSPSFAILPDIEALELGAPTLKNLQKIALFCSSHPVRPEPTAEQDEEEKRAFEEEKRVWTGLFDRVMNGVVDFLRPDKDKELLEQGLVVLWEIVQHQWPLVDDTQRLCHGLFRLRESSDAVVLESTNALISLLVQISDPMLLLCNLRSSLDRFLTKHPAPPSSSADNSDPMTSALSQLSLSSSKESPEKRTRNSGYLFGLTSIGMCVLRLSAPVIVSEGPKLGQIVMEAINDPSSIIRQAAHSLLLAIQCVTHDSRKTLAFVPAMSQGQKDLAVYYMAQNGVLEQIGLHKKATSEGEKGREGDRDNMTGELAGLMSRGVIRE
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein STU1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: CLSA_SALTY
Sequence: MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASSLFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQDDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.