PharMolix/UniProtQA huggingface dataset:
Protein: STK24_MOUSE
Sequence: MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKKTSYLTELIDRYKRWKAEQSHEDSSSEDSDVETDGQASGGSDSGDWIFTIREKDPKNLENGTLQLSDLERNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGASAH
What is the function of this protein?
Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation.  Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress.  Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG.  Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity.  In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation.  Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12.  Acts as a key regulator of axon regeneration in the optic nerve and radial nerve (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane (By similarity).
Protein: HAT2_ENCCU
Sequence: MDNQVLEQKIVNEEYKIWKKNVPYLYDLMFSHTLEWPSLSVQWFPDVRRDEEAGRTTQRLLLSTHTSGSEEEYILIAKVEFPDEFDESLNEEVGGDMRLKIIQRISIMDEANRVRYNPSACNVLAVRSDLPDIHVYDYTKHLSHEKIPRPDMVLRGHSAGGFGLSWNHLNPGELAGCGEGGEVCVFDVSQESSSISPTVVLRRHETAVNDCAFSFFDKKLLSSAGDGGMVVLWDTRSEDCIHAIEEAHTSDILSVRFSPLDGNVIATSSCDGSVKVWDRRSLSQPLHILLGHSKDVVSVEWSPHNDKVLASGSTDRRVIVWDLGQAGAEVPEEYKAEGPPEMKFLHGGHTSTVCDISWNPAEPFEIASVSEDNILQIWQMPQPE
What is the function of this protein?
Regulatory subunit of the histone acetylase B (HAT-B) complex.  The complex acetylates histone H4 which is required for telomeric silencing (By similarity).
What are the official names of this protein?
Histone acetyltransferase type B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MUTS_MARN8
Sequence: MTDLSKHTPMMQQYLKIKGEHPNEMVFYRMGDFYELFYDDAKKAAELLDITLTARGQSGGNPIPMAGVPFHSAEGYIARMVRAGQSIAICEQIGDPATSKGPVERKVVRIVTPGTLSDEAFLEDRRDNLLAAIYHHKEQFGFASLDISSGRFAVSELESLEALQGELQRLRPAEILISEDFPYTDILEGFTGVRRQGPWLFESDTALRVITQQLQVRDLTGFGCEDLTLAVCAAGCLLQYAKETQRTALPHIRKLTRERREDAVILDAASRRNLEIDTNLMGGQQHTLAWVMDRTATAMGARELRRWLNRPLRDVERVRQRQQAVSALLDGFHYEPVHDLLKRVGDIERILARVALRSARPRDLARLRDAFHALPELQEALKPVNSHHVVKLATVIGEYPELADLLERAIIDNPPVVIRDGGVIAEGFDEELDELRNISENAGQYLLDVETRERERTGISTLKVGYNRVHGYYIEISRAQSDQAPVDYIRRQTLKNAERFITPELKEFEDKALSAKSRALAREKGLYDDVLETVAEQLAPLQDAAQALAELDVLSNFAERATSLRFTAPEFTDQPGFDVEEGRHPVVEQLLDEPFVPNNLLMDTKRRMLVITGPNMGGKSTYMRQAALIALLAYTGSFVPANRAVLGPVDRIFTRMGSSDDIAGGRSTFMVEMTETANILHNATEHSLVLMDEVGRGTSTFDGLSLAWATAEHLAKNIRCYTLFATHYFELTQLADDLEHAVNVHLTATEHDDSIVFLHNVHDGPASQSYGLQVAKLAGVPQDVIRNAKTQLAHLEGLEAGSTPSPAPVSVNEPKPAAPTATKAASVEAVYQGDMFAMAEPSVVEQALEKLDLDGITPRDALNQLYELKGLLAK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MSRA_SALEP
Sequence: MSLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGMEIAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYDPAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSAMAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: DFFB_HUMAN
Sequence: MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRKRQ
What is the function of this protein?
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis.  Degrades naked DNA and induces apoptotic morphology.
What are the official names of this protein?
DNA fragmentation factor subunit beta, Caspase-activated deoxyribonuclease, CAD, Caspase-activated DNase, Caspase-activated nuclease, CPAN, DNA fragmentation factor 40 kDa subunit, DFF-40.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDTB_KLEP7
Sequence: MQVLPPGRTGGPSRLFIMRPVATTLLMVAILLAGIIGYRFLPVSALPEVDYPTIQVVTLYPGASPDVVTSAITAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSSAIPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAIAALGLTSETVRTAITSANVNSAKGSLDGPARAVTLSANDQMQSAEDYRRLIIAYQNGAPIRLGDVASVEQGAENSWLGAWANQQRAIVMNVQRQPGANIIDTADSIRQMLPQLTESLPKSVKVQVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNVPATIIPGVAVPLSLVGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSHESLRKQNRFSRASERFFERVIAVYGRWLSRVLNHPWLTLGVALSTLALSIILWVFIPKGFFPIQDNGIIQGTLQAPQSVSFASMAERQRQVASIILKDPAVESLTSFVGVDGTNPALNSARLQINLKPLDERDDRVQTVISRLQQAVDGVPGVALYLQPTQDLTIDTTVSRTQYQFTLQANSLEALSTWVPPLLSRLQAQPQLADVSSDWQDKGLAAYIKVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEQDTEATPGLAALENIRLTSSDGGIVPLTAIATVEQRFTPLSVNHLDQFPVTTISFNVPDNYSLGEAVEAILAAEQSLDFPTDIRTQFQGSSLAFQSALGSTVWLVVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALWLAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMPPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLMLSQVLTLFTTPVIYLLFDRLSLHLKRRFPRQEEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS2_CLOK1
Sequence: MNEKSLRILEFYKVKDELKKYTNTNAAKDLVDNLKPYDNIHDVREHLEETEEALKLIISRGNPPFDGVYDVRQGVKMAQKGSILMPAQIFRIGAILKASRRFEKYIKAKGEGEGFRIIEDICQGIVLLKGLEDKIFISIESEDEISDRASSLLYNIRKSIRDKNASVRDKVNSLIRNYSSYLQDNLYTIRGDRYVLPVRAENKALVPGLVHDQSSSGSTLYIEPMALVNLNNEIKELKLKEKAEIDRILYELSKEIHDNIVVIKNNADIIWELDFIFAKAKFGSELNGNIPIVNDNCIIDIVEGRHPLIDRKTVVPMDVYMGKDFTCLVITGPNTGGKTVALKTMGLLHIMALSGLMIPARENSTVGFFTEIFADIGDEQSIEQNLSTFSSHMTNIINIINNSDEKSLILFDELGAGTDPTEGAALAVSILENLKDRGSMIVATTHYSELKAYALKSNGVENASVEFDVDTLKPTYKLMIGIPGKSNAFEISKRLGLPEFIIKAARENIASEALKFEDLIQSLQEKRIKAENYFREAEILKREAAKIKEKYEQKAIRLQEVRDKSITEAHRKAREIIRESKEEADRILKDIRELEKMGYSSSVKHELEERRKMLKDKLENVEENLYKAKSEDGQRLKSVKEGEEVFIPSLNQKVLVLSKPDNKGEVQVQAGIMKISVNLKELRAPKGSTKNTDKKLKREANLNLRSVATSVDLRGMDSIEAAYITDKYLDDAYVAGLKEVTIIHGKGTGILRSSITNMLKSHSHVKNYRIGEYGEGGTGVTIVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: YR465_MIMIV
Sequence: MSQQQSNNSNDNKEQLDRVIESLNRVNSETKQIVFKMAQGMNEIEIVRSFNQKSCDLFTILINLTKKYRRENDYNVSGYKVLFENAIKIRANLPVDKFTLMILEYAPEIYERDENCFLKMTIPDKKVTLNNEFGVIRSEKFKDLWKVLVQEDKENIADEVTLLTTFAHAYLYKTLLKNSN
What are the official names of this protein?
Uncharacterized protein R465.
Protein: RS13_ELUMP
Sequence: MARVAGIDLPKNKRIDVALEYIYGIGKRNAKDVIAKANGQIDPTTRVKDLTEAQANLLNTILQKEYKVEGELRREISGNIQRYVDTGSYRGNRHRKRLPVRGQRTKTNSRTRKGKRRTVGSKTK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ISPF_SHIB3
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CYSD_ECODH
Sequence: MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: Y223_HAEIN
Sequence: MKFKMKVVTQGILLCIFSQCLFGILYLFSIWLQPLSGTDVFAWRMLTMIFGLLLILFPTIGCRSLLSLITTTLGKSWTRWVLFLLGTLDAGSQFWLFMWAPLNGEGINIAMGYFLFPLIMAVLGWAWLKERLSFIQKIALLLAAAGVAHELWHTQSFSWTSLWVCTVYPFYYLSRKWMKIPALQGITLDIILISIPCFIYILSQSDTLSLVTQEYRYWLLLPALGIVSAISLSANLKSSQQIPVSIFAVLSYIEPILLFLIAVFVLDNQITTSDYFTYVPIWLSLIVIGIEGLLNKKKVR
What are the official names of this protein?
Uncharacterized transporter HI_0223.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_STAAW
Sequence: MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YIDD_TRIV2
Sequence: MKQIFIWLIKGYRMFISPLFPPTCRFQPTCSMYALEAIERFGVFRGGWMGIRRILRCHPFHPGGYDPVPEVGEHCCHHDSGK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LDH_STRS7
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFSKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1_I70A0
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVATTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: QH6_ARTAN
Sequence: MASMCTFSSPFLLCNSSISRTNIVACNKQTSTLQAQVKNVATIETTNRRSANYAPSLWSYDFVQSLSSKYKGDNYMARSRALKGVVRTMILEANGIENPLSLLNLVDDLQRLGISYHFLDEISNVLEKIYLNFYKSPEKWTNMDLNLRSLGFRLLRQHGYHIPQEIFKDFIDVNGNFKGDIISMLNLYEASYHSVEEESILDDAREFTTKYLKETLENIEDQNIALFISHALVFPLHWMVPRVETSWFIEVYPKKVGMNPTVLEFAKLDFNILQAVHQEDMKKASRWWKETCWEKFGFARDRLVENFMWTVAENYLPHFQTGRGVLTKVNAMITTIDDVYDVYGTLPELELFTNIVNSWDINAIDELPDYLKICFLACYNATNELSYNTLTNKGFFVHPYLKKAWQDLCNSYIIEAKWFNDGYTPTFNEFIENAYMSIGIAPIIRHAYLLTLTSVTEEALQHIERAESMIRNACLIVRLTNDMGTSSDELERGDIPKSIQCYMHESGATEMEARAYIKQFIVETWKKLNKERQEIGSEFPQEFVDCVINLPRMGHFMYTDGDKHGKPDMFKPYVFSLFVNPI
What is the function of this protein?
Monoterpene synthase converting geranyl diphosphate to (-)-beta-pinene and (-)-alpha-pinene in a 94:6 ratio.
What are the official names of this protein?
(-)-beta-pinene synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KORA_STRLI
Sequence: MSLERTPPYLQVVAALKAKIVSGELKHGDTLPSVRDLAAQYEISTATAQKVHRTLKAEGLAEAKQGSATTVSTRRTLHRTAADRLESALSTGRIYADGEYAVITSAALAEPPEWVADLLGTESGQAVRRERVTHSADDQPVSASVSWFSADLAETVPALLVRDRIIGGTPSAIEAATGRRAVATEEATTAAAATEDQAALLGVAAGAPVLLSRNVYVDAQGDTIEVGESVAPAGRWRVHRD
What is the function of this protein?
Controls plasmid transfer and prevents the lethal effects of the tra/kilA gene.  Repressor for the transcription of certain pIJ101 promoters, including those the from kilA and kilB loci.
What are the official names of this protein?
Protein KorA.
Protein: ACM3_GORGO
Sequence: MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTDTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCGKKKRRKQQYQQRQSVIFHKRAPEQAL
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover (By similarity).
What are the official names of this protein?
Muscarinic acetylcholine receptor M3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.
Protein: Y387_HAEIN
Sequence: MDYENQIANIFSLNGELSQNIKGFRPRAEQLEMAYAVGKAIQNKSSLVIEAGTGTGKTFAYLAPALVFGKKTIISTGSKNLQDQLFNRDLPAIKKALNFTGKIALLKGRANYLCLERLDQVIAQGVLGDKSVLAELSKVRKWNNSTKTGDFTECIELAEDSPIIPQLTSTAESCLGTDCPNYSECYVASARKKALNADLVVVNHHLFFADMAVKESGFGELIPNAEVIIFDEAHQLPDIASQYFGQSLTSRQLFDLCKDINIVYRTELKDMQQLGTTSDTLLKVVQDFRLLLGNGSNVRGNWRELYTQSAVKKAFELLQEKIDFLSEVIKLALGRSQTLDSIFERVESIKIQLKRLSETNIVGYCYWYEGNGRQFGLHITPLTVADKFGAQLEAKEAAWIFTSATLEVGGTFNHFCQRLGIENATQKILYSPFNYPEQSLLCVPRYLPNTNQMNTLNSLGEILLPVIEANKGRCFVLCTSYSMMRGLAEYFREKSHLSILLQGETSKGKLLEQFIKETHSVLVATSSFWEGVDVRGDALSLVIIDKLPFTAPDEPLLKARIEDCRLQGGDPFNDIQIPEAVITLKQGVGRLIRDVTDRGVVIICDNRLVMRNYGETFLKSLPNSSRTRDLNKVIQFLQNK
What are the official names of this protein?
Probable ATP-dependent DNA helicase HI_0387.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily.
Protein: ZIPA_ACTSZ
Sequence: MDLNTILIILGILALIGLVAHGIWSNRREKSQYFDNENAFHRNPQSTGRPSAQASQPMTPNFAQPAKETEQIRQTYQEPQVRQMSSSPEQQTRPTAQAMPENRAEFNPNTVQPEQQPLDFNAAENIKITLPNTETRAGGAEPIRYEYHAEEERSAPLEQTFNQPVYTEDRAVPDMQVSLRQPAPESPISQPTLQQPVNDAPAYQHSQPAPAEPTDFIMLYVVAPENRQFHGPSLAQALDNLGFIFGQGNIYHRHLDLTVASPAIFSVANINQPGTFNPHGMQDFSTVGVALFMQLPVAGNPRANLKMMIQAAKNLASQLGGFVLTEQQEEFDVMAEAAYLARV
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: FABH_CUPPJ
Sequence: MTKYAKIIGTGSYLPPRRVTNQDLAAQLAEKGIETSDEWIFSRSGISARHWADPDVASSDLAVKAAEQAIEAAGIDRQSIDLILVATSTPDFVFPSTACIIQNKLGINNQCAAFDLQAVCSGFVYALATADKFIRSGSHRNVLVIGTEVFSRILDFNDRTTCVLFGDGAGAVVLSASDEPGILSTAMHSDGSHVGILCVPGNVHGGAIAGNAFLHMDGQAVFKLAVTVLDKVARETMAAAEIQPEQIDWLIPHQANIRIMQGTARKLGLPAERMIAVVHEHGNTSAASIPLALDAAVRDGRIRPGQTVLMEGVGGGFTWGAALLRM
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ONYPE
Sequence: MLLQLQIQLFASKKGAGSTRNGRDSHSKRLGAKLSDGQFAKAGAIIYRQRGTKIHPGFNVGRGGDDTLFAKMSGIIKFEKKHGRKKVSVYLQ
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YHDK_BACSU
Sequence: MELVRIFKEHNVFGWISVGTAVLSLLLLNLAIISNVTFYSYQMLPFAMAAVPFGVVELFIKRGRTGPGLLGVILNLFVIICVYTIVSVDTNLQFGF
What are the official names of this protein?
Probable anti-sigma-M factor YhdK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_NEIMB
Sequence: MSSIKRALISLSDKTGAVEFAQTLHKLGVEILSTGGTAKLLADAGVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLDEHVAKMEEHGIGNIDLVCVNLYLFAATIAKPNCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELEANNGALSDKTRFNLSRKAFSHTAQYDGMISNYLTSLSDDVLSGTPEIAGFPGRFNQSWIKVQDMRYGENPHQRAAFYRDIDPAAGSLAAYKQLQGKELSYNNIADADAAWEAVKSFDVPACVIVKHANPCGVAIASNTLDAYKLAYATDTTSAFGGIIAFNREVDGATVKQITDNQFMEVLMAPKFTAEALEIAAAKKNVRVLEVPLEAGANRFELKRVGGGLLVQTPDIHRISRADLKVVSKRQPTEQEWNDLLFVWNVAKYVKSNAIVFGKGGQTYGIGAGQMSRVDSTRIAARKAQDAGLDLNGACAASDAFFPFRDGVDVIAEQGIKAIIHPAGSMRDQEVFDAADEHGIAMVVTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PDRP_WOLTR
Sequence: MTLKKLNLHLVSDSSGETVISVAKSALKHFRSIETVEYVWSFVKEEEQIDKILEEINKKSNEHNFVICTITNDKLRKYLKDNCVKLKIPYRAILSHIMREISSYLEIEKDEKFDLHTEINNEYFQRIEAINYTINHDDGQNIQDIDKSDIILIGVSRTSKSPTSMYLAYRGYKVANIPFVGEIPFYFDLAKLKDKLTIGLTIDVNRLVEIRKNRLTSINNEDNSIYADPKKVEKEIKKAEELFKQNNWPIIDVTQKSIEEVSATIIQYFNRM
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.