PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_CLOBB
Sequence: MNIKPEEITSIIKKEIEKYEKQIKTVDSGTIIQVGDGVSRVYGLDDCMEGELLEFPNDVYGMALNLEQDNVGCVLLGNEEGIKEGDIVKGSGKIVEVPVGEALIGRVVNSLGEELDGKGPINTNQTRPIEVKAPSIIDRSSVNEPLQTGIKAIDSMIPIGKGQRELIIGDRQTGKTALVIDTILNQKGKDVICIYVAIGQKQSTVAHIVNTLTEMGAMDYSIIVSSTAADSAPLQYLAPYAGCSIGEYFMNQGKDVLIVYDDLSKHAVAYRTMSLLLRRPPGREAYPGDVFYIHSRLLERAAKLSKENGGGSLTALPIIETLAGDITAYIPTNVISITDGQIFLESDLFNSGQRPAVNAGISVSRVGGNAQIKAMKQVTGTLRLELAQYRELAAFAQFGSDLDKDSKKRLEKGKRLVEILKQDQYKPLEVEKQVIILYTAVNDFLSDIKVEDIKKFEKELLEYVDTHYRELGRQIAEEKVLTDEIKAKLEVAIVEFKKIFLQEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ZDHC8_PANTR
Sequence: MPRSPGTRLKPAKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLVYVLNHAEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPELLDRAAPLKVKLSDNGLKAGLGRSKSKGSLDRLDEKPLDLGPPLPPKIEAGTFSSDLQTPRPGSAESALSVQRTSPPTPAMYKFRPAFPTGPKVPFCGPGEQVPGPDSLTLGDDSIRSLDFVSEPSLDLPDYGPGGLHAAYPPSPPLSASDAFSGALRSLSLKASSRRGGDHVALQPLRSEGGPPTPHRSIFAPHALPNRNGSLSYDSLLNPGSPGGHACPAHPAVGMAGYHSPYLHPGATGDPPRPLPRSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQADSLFGDSGVYDAPSSYSLQQASVLSEGPRGPALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRTSSSSLQADQASSNAPGPRPSSGSHRSPARQGLPSPPGTPHLTILRGPQSCRLHPHGPPRATALADRAEDHPQLKTPPSKLNGQSPGLARLGLATGPPGPSASPTRHTLVKKVSGVGGTTYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes.  Through the palmitoylation of ABCA1 regulates the localization of the transporter to the plasma membrane and thereby regulates its function in cholesterol and phospholipid efflux (By similarity).  Could also pamitoylate the D(2) dopamine receptor DRD2 and regulate its stability and localization to the plasma membrane (By similarity).  Could also play a role in glutamatergic transmission (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC8, Zinc finger DHHC domain-containing protein 8, DHHC-8.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Protein: RLMG_STRCO
Sequence: MTTPWGERVLSRFPEDPRDRLRAWDASDEYLLGHLAEREVPLSGTVVVVGDRWGALVTALAPHRPVQITDSHLAREATRVNLERSGVEPGSVRLLTTQDPPPDRVDVLLVRVPKSLALLEDQLLRLAPALHEGTVVVGTGMVKEIHTSTLRLFERIVGPTRTSLAVKKARLIFAEPDPALKRPANPWPLGYRLPDDVGRLSGRPVVNHAGVFCADRLDIGTRFFLRHLPAPGRFRRVVDLGCGNGVVGTAVSLADPDAELLFTDESFQAVASARATYRANEVAGQAEFRVGDGLAGVPDGSVDLVLNNPPFHSHQATTGATAWRMFTGARRVLRPGGELWVVGNRHLGYHVRLRRLFGNSELVAGDRKFVVLKAVKE
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC33_MYCTU
Sequence: MIIPDINLLLYAVITGFPQHRRAHAWWQDTVNGHTRIGLTYPALFGFLRIATSARVLAAPLPTADAIAYVREWLSQPNVDLLTAGPRHLDIALGLLDKLGTASHLTTDVQLAAYGIEYDAEIHSSDTDFARFADLKWTDPLRE
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB33.
What are the official names of this protein?
Ribonuclease VapC33, RNase VapC33, Toxin VapC33.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: MTND1_SORBI
Sequence: MDDSEEDQRLPHHRDPKEFIPLDKLSELGIISWRLNPDNWENDENLKKIREARGYSYMDICDVCPEKLPNYEIKIKNFFEEHLHTDEEIRYCLEGSGYFDVRDENDQWIRVAVKKGGMIVLPAGMYHRFTLDNENYIKAMRLFVGEPVWTPYNRPHDHLPARKEYLDKLLKPEGQAVEAR
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase 1, Acireductone dioxygenase (Fe(2+)-requiring) 1, ARD' 1, Fe-ARD 1, Acireductone dioxygenase (Ni(2+)-requiring) 1, ARD 1, Ni-ARD 1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: G3OX3_ARATH
Sequence: MSSVTQLFKNNPVNRDRIIPLDFTNTKTLPDSHVWSKPEPETTSGPIPVISLSNPEEHGLLRQACEEWGVFHITDHGVSHSLLHNVDCQMKRLFSLPMHRKILAVRSPDESTGYGVVRISMFYDKLMWSEGFSVMGSSLRRHATLLWPDDHAEFCNVMEEYQKAMDDLSHRLISMLMGSLGLTHEDLGWLVPDKTGSGTDSIQSFLQLNSYPVCPDPHLAMGLAPHTDSSLLTILYQGNIPGLEIESPQEEGSRWIGVEPIEGSLVVIMGDLSHIISNGQFRSTMHRAVVNKTHHRVSAAYFAGPPKNLQIGPLTSDKNHPPIYRRLIWEEYLAAKATHFNKALTLFRC
What is the function of this protein?
Converts the inactive gibberellin (GA) precursors GA9 and GA20 in the bioactives gibberellins GA4 and GA1.  Involved in the production of bioactive GA for reproductive development.
What are the official names of this protein?
Gibberellin 3-beta-dioxygenase 3, GA 3-oxidase 3, AtGA3ox3, AtGA3ox4, Gibberellin 3 beta-hydroxylase 3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA3OX subfamily.
Protein: RL27_IDILO
Sequence: MAHKKAGGSTKNGRDSESKRLGVKRFGGESVLAGNILVRQRGTKFHAGANVGIGKDHTLFATSEGKVSFDVKGSKNRKFVSVITD
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GMT_ASPNC
Sequence: MAEGKKTDDYTIQMDSIDQGNKSFEAPPPPQPRSPPSGSLSNNPILPVLAYCGSSILMTVMNKYVLSGTDFNLNFFLLCIQSLVCIIAIQTCKSCGLITYRDFSADEARKWFPITLLLIGMIYTGSKALQFLSIPVYTIFKNLTIILIAYGEVLWFGGSVTGLTLFSFGLMVLSSIIAAWADIKHAVESNGDATAKVSTLNAGYIWMLVNCLCTSSYVLGMRKRIKLTNFKDFDTMFYNNLLSIPVLIVLSAFLEDWSSTNVNRNFPPMDRNSIVFAMILSGLSSVFISYTSAWCVRVTSSTTYSMVGALNKLPIAISGLIFFDAPVTFPSVSAIVVGFVSGIVYAVAKIKQNAKPRTGVLPTANPPVSASSQSMRDSLRS
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter, GMT.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DTD_CHLAA
Sequence: MRAVIQRVREASVTVAGEVVGAIGNGLLILLGVCHTDTAEDVELLAEKIAQLRIFSDHEGKFNLSLLDVGGAALVVSQFTLYADTRKGRRPSFTAAARPEIAAPLVDAFAAALRARNIPVATGVFGAMMQVALINDGPVTLVIDSAELRLPRRAGSRVDS
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMXR1_CRYX8
Sequence: MAPGKGGYKQINKALNICAFEDYLDGQQATLPPLQDVEQISPRVIRVLGQNPGKFTLQGTNTYIVGTGSERLIIDTGQGIPDWADLISTTLLDGNFSLSHVLLTHWHGDHTGGVPDLLRLYPDLISGIYKHTPSKIQQPIEDGQVFKVEGATVRAVHAPGHSSDHMCFILEEEQAMFTGDNVLGHGTSAVEHLSTWMAALQQMKSHNCRKGYPAHGIVINDLQGRITGQLAQKFRRERQVLKALEQVKSQERAMAGGRGKGSVTVKQLVSTMHGDSLDGGIRELALEPFTEEILRKLAEDGKVAFEIRTGIKKWFVVGTALD
What is the function of this protein?
Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
Atrochrysone carboxyl ACP thioesterase dmxR1, ACTE dmxR1, Dimeric xanthone biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: RS5_BRUME
Sequence: MAQRERNREERGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PYRG_SALPK
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGAPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PDXJ_CITBB
Sequence: MARLGVNIDHVATLRQARGGTEPDPVAAAAIAEFAGADGITIHLREDRRHIQDRDLKILRQTVQTRLNLEMAATDEMVAIALAVKPEACTLVPEKRAELTTEGGLDVRIHQEALKVAIEKLQAGGIIVSLFIDPDPDQIKVANKIGADYIEIHTGSFAEAKSWKEEELELIKIENAVKLARKLDLGVNAGHGLSYSNVKKVAAIGGIEEFNIGHSIMSRAILVGLDRAVRDMSELVRYA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1630_DESHY
Sequence: MRRTARIMLVLLGIGLILFIALSGLFEDYLWYSDLGYSQLFWTPLISKGIIQIINGTILFTFIAGTLFSIRHAILTFVNERLRKRLRLVHEMDRPLYHLSQRKMTLWLIIISVLISFGVSFVTGFTGWLEVLTFLNATPFGQGDPIFFKDLGFYVFQLPFFITIYNAFFGPLFFLTFFTIVFYSFAGVIHFQSLLIWKKQAIEINSAARRHLALLITVLFLFKGFGCYFDTFRLLYSQHGLVLGAGYADLHATLPALKALLVLCALGVIGGGLAFFKDEVRLLTLPILAIFISIPLLSGLGPMVLQSLVVIPNELEKETPYIQNEIALTRFAYGLDQISEEDYQADQPLTSETLQKELPTLNNVRLNDPHPLLRTYTQKQGIRPYYKFYNIDMDRYWINGEYRQVMLAPREFSYQDLEKTAQTFVNLRFKYTHGFGVVASFANAVTPEGLPAFAIKDVPPTTDYQELQISQPRIYFGEMTHDWVVVNTDLKEFDYPEGKANAETRYEGKSGIKLTPFNRLMLSIKHGTLRFYLANEINSQSRILLHRNIMDRVEKLAPFLQYDDNPYLVVDEGRLKWIIDAYTVSKTFPYSSMYPERELNYIRNSVKVVVDAYDGTVDFFAVDAQDPILQTYRKIFPGVFKDLSAMPDTLQTHLRYPETLFKIQSTMLKNFHMTDPTVFYNKEDTWDIAKELFGSEPQNIAPYYSVMRLPDSEQPESVLMIPFTPSSNANNIRTNMVAWLAARMDGEHYGELILYKVPKNTEVDGPLQVESRIDQDPEISRQLALWDQKGSSVIRGDLVVLPLAGNFLYVEPIYLQSEKAGSIPEMKRVIVAYGDKIVMSETFEEALAQLFGVRLKLSPPPPANVSALAVSPMSAELKPEETEETTEETEEPVDPQEDTQALLKQIEQIREMLNQLEQQFKKITGDSVDVEGGKKADEDAHDVQTDPEGSVSSEQSKTNP
What are the official names of this protein?
UPF0182 protein DSY1630.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTF_GYNCS
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, GynCa-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLP3L_BOVIN
Sequence: MTTLTHRARRTEVGKNSEKKVESEENVNQDRNQDNEDIGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLERWVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDMAMNRAKDLVELDPEVEGTKHSATEMIWAVLAAFNKS
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
What are the official names of this protein?
Golgi phosphoprotein 3-like.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)- binding mediates recruitment to Golgi membranes.
Protein: LSM4_TOBAC
Sequence: MLPLSLLKTAQGHPMLVELKNGETYNGHLVNCDTWMNIHLREVICTSKDGDRFWRMPECYVRGNTIKYLRVPDEVIDKVQEEAKSRTDRKPPGVGRARARGGRDDSAVGRQPKGIGRGMDDGGAKGRGKGGPSAKSGGRGGGRGRG
What is the function of this protein?
Binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
Probable U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein 10, GRP 10.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLV_SALA4
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RICFE
Sequence: MGMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDEGSDNDKKNN
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLND_ECO81
Sequence: MNTLPEQYANTALPTLHGQPQNPCAWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVISRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLGKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: ISCA_ECOL6
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB (By similarity).
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TSAB_SALTY
Sequence: MRILAIDTATEACSVALWNNGTINAHFELCPREHTQRILPMVQEILAASGASLNEIDALAFGRGPGSFTGVRIGIGIAQGLALGANLPMIGVSTLATMAQGAWRKTGATRVLAAIDARMGEVYWAEYQRDAQGVWQGEETEAVLKPERVGERLKQLSGEWATVGTGWSAWPDLAKECGLTLHDGEVSLPAAEDMLPIASQKLAAGETVAVEHAEPVYLRNEVAWKKLPGKE
What is the function of this protein?
Has been identified as the first Gram-negative bacterial RPF (Resuscitation-Promoting Factor) capable of reviving VNC (viable but non-culturable) cells when added externally, but the million-fold lower activity as compared to Gram-positive bacterial RPFs may indicate a lack of physiological relevance.
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, Resuscitation-promoting factor, RPF, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_DESHY
Sequence: MPSMRKLWIALTFLTRIPLPQPEQVTSEEFTQSQHYYPLVGLILGGALWLALTLLLPHYPPLVTAALLLALELILTGGIHLDGLMDSMDGLLSARTPERMLEIMKDSHVGAFGALSAMVYLLLKFSLLAGLLALSSPLVPYLVLFMPILSRWIFLIGVHYFPYARAQGFGQGFHETSRQTRWLFLGEGLLLLFLTYWVLQWPGIAGFILATLFILLFTRKVSRLLGGLTGDLYGASIELSELLFLLGAFPLLYP
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP5E_IPOBA
Sequence: MASNAAVPFWRAAGMTYITYSNLCANMVRNCLKEPYRAEALSREKVHFSFSKWVDGKPQKPAIRSDTGEE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase epsilon family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.