PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_MARMM
Sequence: MGEDQRNLFIALGLILVILTGYQMFVMGPAEEERRAEQAAVEASQELADPDLPASALEPAAATTVDRETALGGNQRVTIDAPSVLGSLSLTGARLDDVRLRRHTETIDDDTPVALLNPIGSDHVFYARDGWTSATSGFTDLPGGSTEWTLASGSTLTPDTPITLTYDSPSGLHFERVISVDDNYLFTLTDTVTNNSGQEVELSRYGLVRHEGRPEDETRNMAVFEGALAVIDGAMVRSSFGKLEDGNQTEESGTGGWVGITQRYWMAAAVPDQDRPFTARFRTIERGEIDAFEASYVEQAIAVPAGESLASTTRIFAGAKELGVLQQVQNEVGIERFDMAINWGWLWFLTRPFVWLLTMLEGALGQFGLAILALTLMVKIVMFPLANRAYASMAKMKAVQPKMAEIKERYGADQQKQQQALMELYKTEKINPLAGCLPILPQIPIFFALYQTLFNAIEMRHAPFFGWIRDLSAADPTNIWNLFGLIPYDPTGIWLIGGVLGIGAWPIIMGLTMAAQQALNPPPPDPMQARIFAFLPIVFTFILAPFAAGLVIYWAWNNFLSVLQQYIIMRRHGNETQVDKLVARLLKRDRGD
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSB_RICFE
Sequence: MRSIFIVPIFLLFLSSCSEEKTQNKNQEEKQIIVQETLQNNNTSQEINQEAVNSENAAESIVPANDNNQTDEVSTPPSQEQKNPEIKPVKVTFKVDDNDMVLGNKKSNVIVVEYFSPTCPHCAYYHQTIFPELKKKYIDTNKIAYVVREFIATKQDLDAAILARCKGDINSFVQFHNIILQQQDKWAYSNKYRELLTDIGQLGGVPPEEYKQCLNSDKITETLIANTNFVANAPKFIGTPSFFVNGVQTGNYSIDSISTAVDKALEEQKEKAKNEMSL
What is the function of this protein?
May be required for disulfide bond formation in some proteins.
What are the official names of this protein?
Putative protein-disulfide oxidoreductase RF_0032.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ITA7_HUMAN
Sequence: MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
What is the function of this protein?
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers.  During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation.  It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity.  Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro).  Acts as Schwann cell receptor for laminin-2.  Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity).  Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
What are the official names of this protein?
Integrin alpha-7.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AMOL2_BOVIN
Sequence: MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGAGGTGSPQAPMEIMAPEDSQVLQQATRQEPQGQEHQGTETHLAENGLYRLCPQPGKGEELPTYEEAKAHSQYYASQQAGPWPHVGDRDPRGPPGGSRRQDEALRELRHGHVRSLSERLLQLSLERNGARTPSHMSASHSFPQLARNQQGPPARGAPTAEGPEPRGPPPQYPHVMLAHETTSAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLPQQQQQYQYLQQPQERHPPPHLAALSPPGVEGPASTQASLATSGSTHLAQMETVLRENARLQRDNERLQRELESTAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALSNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGTPGGGGGSGGTPELSALRLSEQLREKEEQVLALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRKDPGKVTPGSLRPAKSVPSIFVAAAAGTQGWQGHSSSERQVDASAQLAADRAPLEEPVAVAPLAAHAKHGSRDGSTQTDGPPDSLEPDSLLGCSSGQRTASLDSIATSRVQDFSDMVEILI
What is the function of this protein?
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites.  Required for proper architecture of actin filaments.  Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.  Participates in angiogenesis.  May play a role in the polarity, proliferation and migration of endothelial cells.  Selectively promotes FGF-induced MAPK activation through SRC (By similarity).
What are the official names of this protein?
Angiomotin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the angiomotin family.
What are the subcellular locations of this protein?
Recycling endosome.
Protein: Y567_HELPJ
Sequence: MKAQYFFWILFLIGFYWMLYLYQDFLMDALIAGLLCVGLFQVKVFLNKRFSNVISSFLCVLVLASVVIVPLYFIVYKGSNVIFEINFEKLSALIKWLKGTITENLSHFPAIHDGVSKFLENFSAASITGYLLKVSSYIGKYSLKLVTDALFILGLLFFFFYYGEKFYRYFLGVLPLEMNQSKKIFEEVAGILRIVLLTSLITVILEGVAFGTMIIWFGHDGWSLGILYGLASLVPAVGGALIWIPIAIYELYHGHVNEAIFIVLYSILLIGVLIDSVIKPILIVFIKKRIFKTTLKINEILIFFSMIAGISQFGFWGIIVGPTITAFFIALLRLYENYFIQKEQKTCEC
What are the official names of this protein?
Putative transport protein jhp_0514.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_HAES1
Sequence: MAGIKQHSGLVVPLDAANVDTDAIIPKQFLQAITRVGFGKHLFHEWRYLDEEGTVPNPKFVLNFPEYQGATILLARKNLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIRLNEEEVEEIFQWVWKNKGCEIHVNLENLTVTTGNKIYHFELDEFRRHCLLNGLDNIGLTLQHEDKIAEYEKNIPAFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: DAPD_SALA4
Sequence: MQQLQNVIETAFERRADITPVNVDTVTREAVNQVISLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHN_BRASO
Sequence: MNAHAQACAVTSSSPDGVLRERGQREVFCGLTGIVWLHRKIQDAFFLVVGSRTCAHLIQSAAGVMIFAEPRFATAIMEERDLAGLVDANDELDRIVAQLLARRPDIKLLFLVGSCPSEVIKLDLSRAALRLSQRFSPGVRVLNYSGSGIETTFTQGEDACLAALVPVLPSADRNARPSLLVVGALADVVEDQFKRTFAALGIDNVAFLPPRRSSELPAIGPETRVLLAQPFLGDTARALEERGCRRISAPFPLGGEGTALWLAAAADAFGVSRAHVERTLAPLKARAEKALARYRAQLAGKRVFLFPDSQIEIPLARFLAREIGMELVEVGTPYLHRDHLAAELPMLPAGTLLSEGQDVERQLDRCREARPDLVVCGLGLANPLEAEGLTTKWSIELIFTPIQGFEQAGDLAELFARPLLRQTRLAV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: RL19_CLOBH
Sequence: MLEVIKAIEAEQVRSDLPEFNVGDTVKVHQKIKEGTRERVQVFEGTVLKRQNGGARETFTVRRVAYNVAVEKTFPVNSPLIEKIQVVRKGKVRRAKLYYLRDRVGKAAKVKERI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NDK_AGRRK
Sequence: MAIERTFSMIKPDATKRNLTGAITKIFEDNGLRVIASKRVWMSKREAEGFYAVHKERPFFGELVDGMTSGPTVVQVLEGEGAILKNREIMGATNPANAAEGTIRKIHALSIGENSVHGSDAPETAAVEIAYWFSETEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC2_MACFA
Sequence: MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL
What is the function of this protein?
Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment.  Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.  May bind and mobilize cholesterol that is associated with membranes.  NPC2 binds cholesterol with a 1:1 stoichiometry.  Can bind a variety of sterols, including lathosterol, desmosterol and the plant sterols stigmasterol and beta-sitosterol (By similarity).  The secreted form of NCP2 regulates biliary cholesterol secretion via stimulation of ABCG5/ABCG8-mediated cholesterol transport (By similarity).
What are the official names of this protein?
NPC intracellular cholesterol transporter 2, Epididymal secretory protein 14.6, ESP14.6, Epididymal secretory protein E1, Niemann Pick type C2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum. Lysosome. Note=Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes.
Protein: BTN1_CANGA
Sequence: MNSKQRVYAFFWIFGLVNNVLYVVILSAAVDIVGPKVPKTLVLLMDITPSLLIKVTAPFFIKSIPYTMRIYALIALSCIGMIFVSGKSLLLCMIGIAMASVSSGFGEVSFLQLSHFFEENALNGWSSGTGGAGIVGSSVYMLLTSIFKLPIRLSLLSFTILPFAFLLYFKLDTTQIEYDSISSSGEETLIRNSNSNALQTDTFNESIRLSKTEEQNIFVSSIDHFKSTCVNLKALVVPYMLPLSSVYLFEYLINQAVSPTLLFPLDSRGLPPFFNKYRDMYVTYGTLYQLGVFISRSLAHKFRMHNLYFLSALQGLNLVLTILQAWIYIVHTPWPIMILIFYEGLLGGSSYVNTFLNVLEEVDMDKREFSLGAVSIADSLGVFIAALVGLGLEPTICNHQVSTGRPWCRME
What is the function of this protein?
Involved in vacuolar transport and vacuole pH homeostasis.  Also required for cytokinesis (By similarity).
What are the official names of this protein?
Protein BTN1.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GLGC_RHOP5
Sequence: MTTGIEPPFARHAMAYVLAGGRGSRLMELTDRRAKPAVYFGGKSRIIDFALSNALNSGIRRIAVATQYKAHSLIRHLQHGWNFFRPERNESFDILPASQRVSEELWYLGTADAVYQNLDIIESYDPQFIVLLAGDHIYKMDYEKMLQQHVQQGAHVTVGCLEVPRKEASGFGVMHVDANDQILSFIEKPAHPPAMPDKPDMALASMGIYVFETKFLFEELRRDAADKNSSHDFGKDIIPHIVKHGKAVAHRFDRSCIRSHAESASYWRDVGTVDAYWAANIDLTDIVPQLDLYDHNWPIWTYGEITPPAKFVHDKVGRRGLATSSLVSGGCIISGSTLTQTLLFTGVRIHSFSTIEQAVILPYVEVGRACELKNVVIDRGVRIPDGLVVGEDPELDEQRFRRTENGICLITQPMIDRLDL
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SYDP_ECODH
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: RL20_CHLAA
Sequence: MARVKRGIMVRKRHKKLLEQAKGYRGARSRHYKVAHEAVMHALADAYRDRRRRKRDFRRLWIMRINAAARLHGTTYSRLINSLKQANIEIDRKMLADLAVRDPQAFARIVEQAQAAVTA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: COTH_BACSU
Sequence: MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSDLERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSGETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLSIL
What is the function of this protein?
Involved in the assembly of several proteins in the inner and outer layer of the spore coat.  Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface.
What are the official names of this protein?
Inner spore coat protein H.
What is the protein family that this protein belongs to?
Belongs to the CotH family.
What are the subcellular locations of this protein?
Spore coat.
Protein: DNAJ_SHESH
Sequence: MSKRDYYEVLSVSRDASEREIKKAYKRLAMKFHPDRNPGDKQAEANFKEVKEAYEILTDADKKAAYDQFGHAGVDPNRGGGGFGGNADFGDVFGDVFGDIFGGGRRGGGQRQAARGSDLRYNLELSLEEAVKGLTKELRIPTLAACDSCDGSGAKKGTSPTTCGTCHGQGQVQMRQGFFAVQQACPTCHGRGKIIKDPCNKCHGEGRVEKSKTLSVKIPAGVDNGDRIRLSGEGEAGEFGAPPGDLYVQVSVREHTIFVRDGNNLYCEVPISFSKAALGGEIEVPTLDGKVNLKIPAETQTGRMFRMRGKGVKSVRSHAVGDLLCKVVMETPVKLNERQKELLREFDETLTGSSSKKHSPKAEGFFDGVKKFFQDLNS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAP_SALTI
Sequence: MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
What is the function of this protein?
Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
What are the official names of this protein?
Surface presentation of antigens protein SpaP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPX_HALH5
Sequence: MGKRILFFLLTNVLVMTTIVIVWSIISRFTNFGGSFETGGPGLGIDYASLMVFSLLVGFTGAFISLAMSRWMAKKMMNVKVLDPNGPLTERERFVVEKVHRLSRAAGLMHMPEVGIYQSAEVNAFATGPSKKRSLVAVSSGLLDAMDDDAVEGVIAHEVAHISNGDMVTMTLLQGVVNTFVVFLSRVAAIIVSRFVRSELQWIVQFAAIIVFQILFSILGSIVVSAFSRYREYHADRGGADLAGRDKMAHALRSLKAYLDRTKLNDGTDDSAVQTMKISGRGGVMKLFSTHPDLDDRIARLEQR
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
Protein: DPOL_HBVB3
Sequence: MPLSYQHFRKLLLLDEEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPCFNPNWQTPSFPDIHLQEDIVDRCQQFVGPLTVNENRRLKLIMPARFYPNVTKYLPLDKGIKPYYPEHVVNHYFQTRHYLHTLWKAGILYKRESTRSASFCGSPYSWEQDLQHGRLVFQTSKRHGDKSCCPQSPGILSRSSVGPCIQSQLRQSRLGPQPAQGQLAGRQQGGSGSIRARVHPSPWGTVGVEPSGSGPTHNCASSSSSCLHQSAVRKAAYSLVSTSKGYSSSGHAVELHHFPPNSSRSQSQGPVLSCWWLQFRNSEPCSEYCLCHIVNLIEDWGPCTEHGEHLIRTPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRANTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRIINNQHRTMQNLHNSCSRNLYVSLMLLYKTYGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYAAVTHFLLSLGIHLNPHKTKRWGYSLNFMGYVIGSWGTLPQEHIVQKIKMCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLRNQYLNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVSPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLLYRPTTGRTSLYADSPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: AGO8_ARATH
Sequence: MDTTLPPPQHMEREPLKSKSSLLPMTRRGNGSKGQKILLLTNHFRVNFRKPNSHNFFHYSVTITYEDGSPLLAKGFGRKILEKVQQTCQADLGCKHFAYDGDKNLYTVGPLPRSSLDFSVVLETAPSRRNADKRLKLPHQSKKFNVAILFAPPEIPMEAIANALQGKKTKHLLDAIRVMDCILSQNAARQGCLLVRQSFFHNDAKYFANIGEGVDCCKGFHSSFRTTQGGLSLNIDVSTAMIVKPGPVVDFLIANQGVNDPFSINWKKAKNTLKNLRVKVLPSNQEYKITGLSGLHCKDQTFTWKKRNQNREFEEVEITVSDYFTRIREIELRYSGGLPCINVGKPNRPTYFPIELCELVSLQRYTKALTKFQRSNLIKESRQNPQQRIGVLTRALKTSNYNDDPMLQECGVRIGSDFTQVEGRVLPTPKLKAGKEQDIYPINGSWNFKNKPATVTRWAVVNFSARCDPQKIIDDLTRCGKMKGINVDSPYHVVFEENPQFKDATGSVRVDKMFQHLQSILGEVPPKFLLCILEKKNSDVYEKSCSMWNCECIVPPQNLNDQYLTNLLLKINAKLGGLNSVLDMELSGTMPLVMRVPTIIIGMDVSHGSPGQSDHIPSIAAVVSSREWPLISKYRACVRTQSPKVEMIDSLFKPVSDKDDQGIMRELLLDFHSSSGKKPNHIIIFRDGVSESQFNQVLNIELDQMMQINHHTKFFQTESPNNVLPGTIIDSNICHQHNNDFYLCAHAGKIGTTRPTHYHVLYDEIGFDTDQLQELVHSLSYVYQRSTTAISLVAPICYAHLAAAQMATAMKFEDMSETSSSHGGITTAGAVPVPPMPKLNTNVASSMFFC
What is the function of this protein?
Involved in RNA-mediated post-transcriptional gene silencing (PTGS).  Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA).  RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity).
What are the official names of this protein?
Protein argonaute 8.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: BIOF_NITOC
Sequence: MELRQRQTQSLYRYRRVLEGPQGAELQMDGRRILAFCSNDYLGLANHPATRAAFMQGVREYGVGSGAAHLVTGHSRAHHTLEEALAAFVGRPRVLLFSTGYSANLGVISALIGRQDAVFEDRLNHASLLDGGLLAGARFKRYRHRDYQSLEAALTATKARRRLVVTDGVFSMDGALAPLPDLAAVADRFDAWLMVDDAHGLGVLGEEGRGSVAHFGLGMAQAPILVGTLGKALGTFGAFVAGEEALIETLIQQARTYIYTTAPPSAVAVATLASLRLVETESWRRDKLTRLIAQFRQGAAQLGLQLVDSPTPIQPLLVGDAGAAVKLSERLLAQGILVTAIRPPTVPEGSARLRITLTAAHSEAQVARLLESLVQVL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RL6_STRCO
Sequence: MSRIGKLPIAVPAGVDVTIDGRTVSVKGPKGSLTHTVVAPIDIAKGEDGVLNVTRPNDERQSKALHGLSRTLVANMITGVTQGYVKKLEISGVGYRVLAKGSNLEFSLGYSHPILVEAPEGITFKVENPTHFSVEGIDKQKVGEVAANIRKLRKPDPYKAKGVKYEGEVIRRKVGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MURI_VIBCM
Sequence: MSSPSFPRVLIFDSGVGGLSVYREIEARLPQLNYIYLFDNAAYPYGELTQETLIARVDTLVTRMVEQERIDLVVIACNTASTIVLPVLRAKLTIPVVGVVPAIKPASLIASKAIGLIATPATVKRQYTQELIRDFSANKNVELLGSTRLVNMAEEKLRGKPLDLEELASILQPLKNTIDVAVLGCTHFPLIKEEIQQVLGEQVQLIDSGLAIARRVQELLGIEQAVGAKQKHRIYASAPPWEESALNIKLEQLGFNPVQPFLHPI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.