PharMolix/UniProtQA huggingface dataset:
Protein: LOLC_ECOL6
Sequence: MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGDQIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGNITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGALLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
What is the function of this protein?
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity).
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolC.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_LEGPH
Sequence: MKKIDELRNMSVEELQNELLSLRKDQFNLRMKKASGSLDKTHLITMVRKSVAKVKTILTEKAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LPXA_HELAH
Sequence: MSKIAKTAIISPKAEVGKGVEIGEFCVIGDGIKLDDGVKLHNNVTLQGHTFIGKNTEIFPFVVLGTQPQDLKYKGEYSELIVGEDNLIREFCMINPGTEGGIKKTIIGDKNLLMAYVHVAHDCVIGNHCILANGVTLAGHVEVGDYVNIGGLTAIHQFVRIAKGSMIAGKSALGKDVPPYCLAEGNRAFIKGLNRHRMRQLLESKDIDFIHALYKRLFRPVLSLRESAKLELEEHANNPIVEEICSFILASSRGVAYKSSEYSSEEKQED
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y315_THERP
Sequence: MRVAYVDPFSGASGDMLLGALVDAGVPPEELADRLASALDVDGYRLVVERVVRRGLAGTQVRVIVEAAQPARDWAEIRDLLSASALPPRVKERALAVFRRLAEAEASVHSVPLESVHFHEVGAVDSIVDVVGVVWGFELLGVEEITCGPLPLSRGWVETAHGRLPVPAPATALLLAQAGAPLVPLDIEAELVTPTGAALLVELARFVRPAFLPERVGYGFGTRELPWPNALRLWIGEAFAVPSRLDEAELLLEANLDDMNPQFIEPLVDQLFAAGALDVYLTPIVMKRSRPAVIVSAICRAKDRPVLERVLFEHSTTFGVRGIPIERTKLARRSVAVATRWGEVAVKLKIVQDRIVDAVPEYRDCLAIHQRTGLPIREIWNEAARLAAVWIGQRVGEEDQEATLPE
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: 5HT3B_HUMAN
Sequence: MLSSVMAPLWACILVAAGILATDTHHPQDSALYHLSKQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYKPIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTSVLVGYTVFRVNMSNQVPRSVGSTPLIGHFFTICMAFLVLSLAKSIVLVKFLHDEQRGGQEQPFLCLRGDTDADRPRVEPRAQRAVVTESSLYGEHLAQPGTLKEVWSQLQSISNYLQTQDQTDQQEAEWLVLLSRFDRLLFQSYLFMLGIYTITLCSLWALWGGV
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses.  It is a cation-specific, but otherwise relatively nonselective, ion channel.
What are the official names of this protein?
5-hydroxytryptamine receptor 3B, 5-HT3-B, 5-HT3B, Serotonin receptor 3B.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Protein: TOLIP_MOUSE
Sequence: MATTVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQQLQYGGTVGTVGRLSITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQGVGYVPIAGMPAVCSPGMVPMAMPPPAVAPQPRCNEEDLKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEES
What is the function of this protein?
Component of the signaling pathway of IL-1 and Toll-like receptors (By similarity).  Inhibits cell activation by microbial products (By similarity).  Recruits IRAK1 to the IL-1 receptor complex (By similarity).  Inhibits IRAK1 phosphorylation and kinase activity.  Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates (By similarity).  The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).  In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity).  Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P) (By similarity).
What are the official names of this protein?
Toll-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the tollip family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COR14_PAPSO
Sequence: MESNGVPMITLSSGIRMPALGMGTAETMVKGTEREKLAFLKAIEVGYRHFDTAAAYQSEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLEYLDLYLIHHPVSLKPGKFVNEIPKDHILPMDYKTVWAAMEECQTLGFTRAIGVSNFSCKKLQELMAAAKIPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAIGAPWGSNAVMDSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEGRMKENLKIFDWELTAEDMEKISEIPQSRTSSADFLLSPTGPFKTEEEFWDEKD
What is the function of this protein?
Reduces codeinone to codeine in the penultimate step in morphine biosynthesis.  Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as cofactor, and morphine and dihydrocodeine as substrate during oxidative reaction with NADP as cofactor.
What are the official names of this protein?
NADPH-dependent codeinone reductase 1-4.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex.
Protein: CP2CS_MESAU
Sequence: MDPVLVLVLTLSCLLLFSVWRQSSGRGRLPPGPTPLPLIGNILQIDIKDISKSLANFSKVYGPVFTLYFGTKPTVVVHGYEAVKEALEDLGEEFSGRGNFPIVERMNSGLGIIFSNGTKWKELRRFSLMTLRNFGMGKRSIEDCIQEEARCLVEELRKTNGSPCDPTFFLSCAPSNVICSVVFHNRFDYNDKNFLNLMEKLNENFEILNSPWLQVCNVIPAFLDYLPGSHNKALKNFAEIKSYILKRVKEHQETLDMNNPRDFIDCFLIKMEKEKDNPHSEFTTESLMATVADVFVAGSETTSTTLRYGLLLLLKHKEVTAKVQKEIDHVIGRDRSPCMQDRTRMPYTDAMVHEVQRYVNLIPNNVPHAATCNVKFRNYVIPKGTDLITSLTSVLHDDKEFPNPKIFDPAHFLDENGNFKKSDYFMPFSIGKRMCMGEALARMELFLLLTTILQNFDLKSLADTKDIDTTPVASTFGCVPPSYQLYFIPR
What is the function of this protein?
Catalyzes the N-demethylation of aminopyrine and benzphetamine, but does not catalyze the hydroxylation of tolbutamide, testosterone, and progesterone.
What are the official names of this protein?
Cytochrome P450 2C28, CYPIIC28, Cytochrome P450 HSM4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PFF1_LACTC
Sequence: MLAQFLRSLFRFRKTTVSVLLVATYVVVFLLNVWDRIRYQYSLPEDNKHHKQLLDASWIDLQSITRKPHPYTSRENDAVHDFLLHRVTELVEGAPHAEVSDDYKEGNHLVFKQPDVFNSSSTESRIVSFESSNIVVKITGSQPELPGLLISAHFDSVPTALGATDDGVGIVTLLALITRYAKKQPRRTLVFNLNNNEEFGLLGASAFLNHRWRPLVDYVLNLEGTGAGGKAVLFRTSDTNTASIYKNAVKTQPFGNSIYQQAFYDRYISSETDYKVYEQAGLRGWDIAFYKPRALYHTIKDSTQFTSQASLWNMMHASLQLADFIAFESFEDEPKDRSPAVYFDIIGTFFVTASTKDLFTLNCVVLSVIPVIILVLEFVIQRRKTRERNPLLVWLRLPFSMFISYLVTATFRSSLFRVNPLIFSRDYVSPTIGFSFTFLILNYLVLSLLEYLAPSRDLKTVSFVELFFGMWIALLWATIRLCTSKYTATGVYPITVLYLLMSFGAIVGLVCSAFKRKHSVVKAKDSEETAAPNTYSSIEESPQQATNTEAPNENSPEEHDERAPLLRASNSSQVSSVTNVSEAPSSALKAFVVSALNYDWSVQFLAVVPLASFFVIMCLSLILDGIYQTCQEGFQATWNVSKISMLGGMLLAIPVLPFCYKLNYFVSMVLLFAAASAGIFSFERAPFTESSPLKLRFSQELNLHDELGFSTVNVFGRQGAGIEQILRNIPSTQNAHSNVECTSNGQGSETCRYAGPRPHLVSSSSIPELSDILSIKVLSNNRKSSGRSSYEPINAELVINVKENRLCTIGFNSSQFAEHDYGQSPVKQVTIFGNAHHDNRTRSQLSTLDGLSRDDEENRIFKWNRGINSLQLHKLDFERNYYHVGIQWMPTILSQDADEESSDALGLKIRCFWGEYDSVSIINGEVKRKVPALDELLAYSPKEVSFSNREAGLVIVNDYIEL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: COAD_EXISA
Sequence: MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTTHLPNVSADAFGGLLVEYAAEREAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMTNSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQVSSGQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXF27_CTEON
Sequence: RACIELGEDCDGYKDDCQCCRDNAFCSCYEFFGEKNGCGCAVGH
What is the function of this protein?
Omega-agatoxins are antagonists of voltage-sensitive calcium channels (Cav) (By similarity).  Toxic to mice by intracerebroventricular injection.
What are the official names of this protein?
U17-ctenitoxin-Co1a, U17-CNTX-Co1a, Neurotoxin Oct F27-10.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 03 (type II/III omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PPK6_DERER
Sequence: SDPEVPGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-6, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFLD_PSEF5
Sequence: MSPIQEQLTALGGVFLAAVLVDRIAKTGQVSEAALSCMLGSLLIRDPKDTLEVYGGDDINLREGYRALIGALERDPSTLQREPLRYALSMLGLERQLAKRDDLLETIGKRLPQIQSQVEHFGPAHENVIAACGGLYQDTLSTLRQRIQVHGDMRNLQQPSNASKIRALLLAGIRSARLWRQLGGHRWQLVISRRKLLKELYPLMRSS
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS7_BURM1
Sequence: MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MURB_CHLT3
Sequence: MISIADLREVFRGDVKISASLAEHSAFKIGGKADIVLKPLDKADAINVIKFFHEKQKPHIVLGRGSNVLISDDGVREAVILLSGCLEKVDINGELVYAEAGVDLQKLAVQSLNHRLGGLEAFSGVPGSVGGAIVMNAGAHGHEIFELIDWVEVVRDGSLKKLRKNEIKARYRETDLAQDTVLSARLKLKPISEKEQAECFERRRELMEKRRNSQPLSLPNVGSIFKNPPPYNGESRQFAGQLIEACGLKGVREGGAMISDKHANFIVNLGNATASDVLALIELAKTKVRLRFGIDLELEIKLIGFTEHVEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_BURPS
Sequence: MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYLM_SCHPO
Sequence: MLKSVGTNGRKVPKIASLCNFLKFNKNIHSNPDFLAIAENWKSYWKSHYPFVKNDKGKKKYILSMFPYPSGLLHIGHVRVYTISDILSRYYRMKGYKVIHPMGWDAFGLPAENAAIENGISASSWTYENIKKMKEQTYHMNIYFDWDREISTCNPDYYKWSQYLFLQMFHKGLAYQAEATVNWDPVDCTVLANEQVDSHGRSWRSGAIVEKKNLRQWFLKISDYSDQLLDDLETLPKWPDKVKKMQRNWIGRTTGFEISFPLLNDKETLTVFTTKPETIIDVSFIALSKNHKLVLLESQKDPSLAEHLRNESLLDKGYQLPCFAKNPVTGKALPIFYAPYVLDCYGTGAVMGAPIHDRRDFEFAKRNNIIFSKESCIGSYFTNEGKELLNHHDSSNLMDIKQKMLQQKIVSYLEEKKLAKRVKNYRLKDWLISRQRFWGTPIPMVHCETCGAVPVPESELPVKLPDLDKIYEKGTSPLSNLETWMKTTCPKCHGPATRETDTMDTFVDSSWYYFRFLDSKNSELPVGLASASSLMPVDIYIGGVEHSILHLLYSRFFSKFMKDIGLWNGDKYLNEPFTQLITQGMVHGLTYTTMSDERILNPKEVQKIGDEYFLISNPKEKVQLSYQKMSKSKHNGVDPIRTIQKYGSDIIRAYIIFSAPVEGVLLWNENAIMGTKRWLTKIWNCVHQLLEREKKMSDAMRQTKLTIVDDHNSRKLESQYNEFISQCSAHYENVFSLNLVISDAMKLTNNIADALKNNKVNIGTIKASLEVLVKCIAPIIPCFSSECWLLLGHNSSVYSNWPISKNKKENMEEPVTIPVQINGKVRFKIEMPKLNDENEILNFVLETNDGKRWLSNKKVLKSFVKQKIISLVTD
What are the official names of this protein?
Putative leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNH2_SHIF8
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEYGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC13_ARATH
Sequence: MDLSVENGGLAPGFRFHPTDEELVVYYLKRKIRRKKLRVEAIGETDVYKFDPEELPEKALYKTRDRQWFFFSLRDRKHGSRSSRATERGYWKATGKDRVIHCDSRPVGEKKTLVFHRGRAPNGERTNWVMHEYTLHKEELKRCGGEDVKDAYVLYKIYKKSGSGPKNGEQYGAPFIEEEWAEDDDDDVDEPANQLVVSASVDNSLWGKGLNQSELDDNDIEELMSQVRDQSGPTLQQNGVSGLNSHVDTYNLENLEEDMYLEINDLMEPEPEPTSVEVMENNWNEDGSGLLNDDDFVGADSYFLDLGVTNPQLDFVSGDLKNGFAQSLQVNTSLMTYQANNNQFQQQSGKNQASNWPLRNSYTRQINNGSSWVQELNNDGLTVTRFGEAPGTGDSSEFLNPVPSGISTTNEDDPSKDESSKFASSVWTFLESIPAKPAYASENPFVKLNLVRMSTSGGRFRFTSKSTGNNVVVMDSDSAVKRNKSGGNNDKKKKKNKGFFCLSIIGALCALFWVIIGTMGGSGRPLLW
What is the function of this protein?
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP).  Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction.  Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'-CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance.
What are the official names of this protein?
NAC domain-containing protein 13, ANAC013, Protein NTM1-like 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Localized primarily in endoplasmic reticulum membrane as dormant form and, upon oxidative stress, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Protein: Y902_RICBR
Sequence: MDTAELSKVDDGWTVLTFAAAYGLEKVCEALIPKMSEQAINHVDKDGNTALTWAAYTGLEKVCEALIPKMSDQAINHVNSDGNTALSIARNKGFKNMCDLLTTIEATKQNEIQTNLKLTTTKTSHEKLIEAIEARNEAEAQNLIVHMDTAELSKVNNDDWTALTFAAAYGLEKVCELLIPKMTDQVINHVDKDGDTALTWAASSGLEKICEALIPKMTEQTINQLTDNNDTVLTLAANKSLGKICEILIPKMTDQAINQVNKDGNTALIAAASSHLEKICEALIPKMSDQAINHINNYGNTALIAAASSGLEKVCETLIPKMTEQAINQANHQCDTALIFAVRNSLKKVCEVLIPKMSYEAINCWSTNSFWFGFTAFTWVTLNGDKKICELLIPKTSPEVIIDILKLTKEKQFIIEAINSCNKTSPEVIINILKLAKEKQFMIEAINNYNNKLVKELNLILDENNPNNAIKMIRAVKIYKKLFKEYLTVEKTENFKPLQNTIEDFIKNNFFTAAGVCKNLIPKIDNNEIHISCLTTEIIAHIVEYLENEKWGLEVETLG
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0902.
Protein: ATM_CAEEL
Sequence: MSVTQLKNLKHAIAQLLEWDGTKTARKKIVDEVVLLYHALGAEALSEDNQEIYDLYDLSARIFNLAKKEIEEANQQFEKERKKGTRRSEKPVPTPLFELSIQHLKRCCQQGIDHNQVPWIAYCLKLLEFPITITEKSIENEISNVLLLSSNASQLHWAEHAHLSSLWKWIWSRVETADIGALAMRNYMELAANLLENVDYVVFEKSPIDLMAKVMGTLKKSVEMGNPKEYWCHYRKFSVVHILSYIVHRWGLEARDFILREIFELTGSLSNLISVAHKDGEQSKKCIMRLIDDLVKLAMIETVHGHRTMNEVTRGNIQKLVKTGIQESLKSAHRNFSRSSTFSISEECVRYLTRWLLAERRLEQPSAAMNESFELTGDSSSKKKDDATFDSLIDLSFGSTISGKHKLNAWNGVMQILNELLKSRRLELQVTEKIVTILWEKRKSYTTEPLRTVFCSILSTVVCQADVRFGHRKVPTIDSILKYSLSLMPNVASLPSAAALTETIVRFRTVSREGLRNTWDTVSRTSSGSFEVVRLISALISVTEFDENSRFANDERVRSWSFRKDIIEWVLLDPNAHSHKLLYQLCQYHPTYCYESEASSSDDSLLQTLKLCKLACSPAPPSAPKALRPLEASIEEIVRYVHDKLKSILATEITLPAFVLCHEFALKYPDRSYEFNKMYKKLYQIMEDQEEDEFLQSARHFSKWPQNLTLPIQKQTINCMAVFFEANLDNQLVDLCQWSDRRKVLVEMLAELAATRSEIRDKLQKSMPFNKFVKECIMENRGDLYEMTKRFEKYSFLLSIRNLIVTRMIITNEAARLLGDGETISETDIFIIEKRTLSTCIRNVSEGKELSGYTLDPYTVAANVHNVHFDHINVEIYLELLKKSPFFAQNIVRHLLRQNGKEAEEETWHLHATVLKIVMKDEKLLAVCVATIPNMVRYLKVYQIHFSPKSNAAKFLHLDMESISHCQSYLRKPTKSSNLITAANFLTLFGCEKRTWKRPILRFWSIFKQQPAMCCEKLLIFAEECVELGLNHRIACLLRALTTSEFCRKALCDEYLKIAFQLTYRSIFLILSKNECRPEIVELCDDMNLRYDLLQHQIKHVAAHHLEHFERFETKIAFSVEKFLKSGIDGIDFEDLGLVEFYKQLNENLTEDAIRSNEARNIYIVDILSTIWLQLPSIRPQILPILARFKHISPAWTNFPQPPHISTNEKSFLQHLRFHLYLKMMNISKSMTQGEYATCIMMLLTSYDSSHFVADLIEKKQLGKLKLQQRRNVLCILSRLLKDQAVMGDEDETIIDPILFKAITKASAVFEDTAACIVPFLFKICVDFKGKYDKCVINLLGCLKGVNAEDEIVVRCLAECVDSIGLNVIARYERLNIETHSEFGVKWFFKLSRLFLKHGFTTHSFAIANILFDRLSARKRNTMMIDRTSLDRIDRSQELINLLVEIYVAEGNSVALSSLPPAVQNRPDVRQVMNKSSKEWLKLLSSNQMDSWELTIVQWMCGIQFNAITGDKYLNSILRCNFNEYTKKIDSPLKFVYFQLFHLSTSTLEIEEAISSMPLAPTIDQMRLMIIANATASFEPQSVEEHVVRAVRELRETSNRRKSGGNVKGINEKTTRMVKLAEMLTENKAYDAAINLLDTWEHECLQWTSVAAESIDIDLIRICKQHVTCRSGDPRMADINLRTMHPRVPVMSDLAIAEWSLALSKITIEYRNDMEEGIRILEFGCKHLQNKDSVETRLKVLLKLHSVCIGQLSKLEEYRETRTYRMKQQAVTAFEQQIQNSCRTSLARGNSGDEWTKKTVQRVRKEHQFEKNDLEKVDNSLNSAARKAVSSGFDALLCISQLEDDDEAIRASSLIIFPLIDVIYKYETDVGVIALLKEHTKSKLPSKLWISATSHIASKCFSIEKSQITRHLSQILCHLIYDYPYHVLHTILMYDDEKNASKVKGFLKTIFDARADQRDSSKLKEIVITIREAHQAYREIAMLDVRGNVRIQRVEINGKTMYRWPHDLKIFKCKLRQLPIPTISQKIGCPGDYSTTDLITWKRWKDVFTIADGISTPKIWEIEGSDGKWYKTVWKKDDVRQDVLVEQMFDVTNNMLEKAMLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTREGGLHREFNSEEVSASKVSSMMRQVQTESTETRRQVFVEICQQYSPVFRHFFYTNFSTAQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTLPVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALLRETMTNFREAEQAAGRPSYISEMAIGRLREKLRGTDDGVTAQSSNLQIRRLLREATSADNLSRMFCGWMPFL
What is the function of this protein?
Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV.  Plays a role in maintaining genome stability.
What are the official names of this protein?
Serine/threonine-protein kinase ATM.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. ATM subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y206_METJA
Sequence: MEFIIKAKGHKNVSATHKTTLEITKEDYLTPTGHCIIGIDADKSMTDFSEEFKEKLRNAKKIIVEIEVEGIKDTIIGEGHKDLILNHPTDMVIRKSNYICPRTLMINANKSAKDINREIVKKLKEGKELIFKIIV
What are the official names of this protein?
Uncharacterized protein MJ0206.
Protein: PTH2_DROME
Sequence: MGDKLLDPTQIINGLAVMLSFFVGYRYALKRGDAKDSVTEGAATPFSQESSVSSGSEASVSDKGYGGLNDNFKMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAELMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Probable peptidyl-tRNA hydrolase 2, PTH 2.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
Protein: RNPH_YERPS
Sequence: MRPADRAAQQVRPLTLTRNYTKHAEGSVLVEFGDTKVLCTATVEEGVPRFLKGQGQGWITAEYGMLPRSTHSRNAREAAKGKQGGRTLEIQRLIARSLRAAVDLKKLGEFTITLDCDVLQADGGTRTASISGACVALADALNKLVASGKLKANPMKGLVAAVSVGIVKGEALCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLALLDLARGGIETIFQAQKAALES
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CH10_STREM
Sequence: MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSETGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACATN_MOUSE
Sequence: MSPTISHKDSSRQRRSGMFSHALDMKSGPLPPGGWDDSRRDSVGGEGDREVLLGDAGPGDLPKAPRSYRSELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYTLGIFMIYLSTQVDRLLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENREASIVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPLYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAIELCKKLGGSCVTALDGYYVESIICVLIGFGWWFFLGPKFKKLQDEGPSSWKCKRNN
What is the function of this protein?
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:10570973).  Negatively regulates BMP signaling (By similarity).
What are the official names of this protein?
Acetyl-coenzyme A transporter 1, AT-1, Acetyl-CoA transporter 1, Solute carrier family 33 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC33A transporter family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.