PharMolix/UniProtQA huggingface dataset:
Protein: RS7_ECOUT
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CDUB1_CHLT2
Sequence: MLSPTNSTSKTAPVPPRDSSKPVLISEEPRNQLLQKVARTALAVLLVVVTLGLILLFYSFSDLQSFPWCCQTHPSTKEQPTISIPVPLPSPPLAVPRPSTPPPPVISRPSTPSAPKPSTPPPLLPKAPKPVKTQEDLLPLVPEQVFVEMYEDMARRQTIEALVPAWDSDIIFKCLCYFHTLYPGLIPLETFPPATIFNFKQKIISILEDKKAVLRGEPIKGPLPICCSKENYRRHLQRTTLLPVFMWYHPTPKTLSDTMQTMKQLAIKGSVGASHWLLVIVDIQARRLVYFDSLYNYVMPPENMKKELQSFAQQLDQVYPAYDSKKFSVKIAAKEVIQRGSGSSCGAWCCQFLHWYLKDPLTDALNDLPVDSVERHENLASFVQACEAAVQDLPELSWPEA
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease possesses deubiquitinating and deneddylating activities (By similarity).  Impairs ubiquitination and degradation of NF-kappa-B inhibitor alpha (NFKBIA), thereby preventing NF-kappa-B activation.
What are the official names of this protein?
Deubiquitinase and deneddylase Dub1, ChlaDub1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Secreted. Host cell. Membrane; Single-pass membrane protein. Note=Secreted, and delivered into the host cell. Located predominantly on the plasma membrane and to a lesser extent on intracellular membranes, especially the host cell nuclear envelope.
Protein: TOP6A_AERPE
Sequence: MSGEMFGDEVDIKARLRAAEVMYKKFHRLISDVIKGRPPKLEIPKRTLSNTIFDPERGILVIGEEKLEREFLNVGESRRFMQTLLMASIIYQSLIENEYPTIRDLYYKGKHTIVYRDYSGRKREENTWDEQKESDSVIQDIEVYTGLFREDMLILSKEKGKVVGNMRIRSGGDVIDLSKLGHGAYAIEPTPDLIEFLDVDAEFVLVVEKDAVFQQLHRAGFWKKYKALLVTGSGQPDRATRRFVRRLHEELKLPVYIITDSDPYGWYIYSVYKVGSITLSYESERLATPKAKFLGVQMTDIFGYRGKKPYLSEAERKKFMIKATDKDIKRAKELLNYSWIGKNRRWNVEIRLFLKHLVKLEIEAIASKGLKFFAYQYIPEKIETGDWID
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: HSLO_BACAC
Sequence: MKDYLVKALAFDGEVRAYSVRTTNTVSEAQRRHDTWRTASAALGRSLTAGTMMGAMLKGDQKLTIKVEGNGPIGPILVDAHANGDVRGYVTNPHVDFEGTEQGKLRVYQAVGTEGFVTVIKDIGMREPFIGQSPIVSGELGEDFTYYFAVSEQTPSSVGVGVLVNGDDSILAAGGFILQIMPGAQEETISFIEERLQKIPPVSTLIEQGLSPEELLYAVLGEDKVKVLETMDVQFNCTCSRERIESVLISLGKTELEQVREEEEETEVHCHFCNERYKFSKEDITNLIENL
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXC_ECO57
Sequence: MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFVIPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSALAELSVIIDADGEDCWIPRDGWADYRSRRREELIERIHQFGVAGLGGAGFPTGVKLQGGGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKPQAISMLRAVLADSHDISMRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLLPQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEEKRAAEAKARFEARLARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQATQPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVTDPRKTAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEEPVDPRKAAVEAAITRAKARKLEQQQANAEPEEQVDPRKAAVAAAIARAKARKLEQQQANAEPEEQVDPRKAAVAAAIARVQAKKAVQQKVVNED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KCD11_HUMAN
Sequence: MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLWTGGPGERREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH
What is the function of this protein?
Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor.  Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B.  Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB).  Acts as probable substrate-specific adapter for a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex towards HDAC1.  Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcription factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive.  When knock-down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained.  Activates the caspase cascade.
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD11, KCASH1 protein, Potassium channel tetramerization domain-containing protein 11, RING-type E3 ubiquitin transferase subunit KCTD11.
Protein: RL3_CHLPD
Sequence: MGAILGKKIGMTRLYNDKREAISCTIIQAGPCFVTQVKHAEKDGYDAYQIGIGERDEKKVNKPMLGHYKKAGVTPGYKIAEFSKSEINLELEAGAPLDLSVFKEGEKINVLGVSKGKGFAGVVKRHNFGGGSRTHGQSDRLRAPGSVGGSSDPSRTFRGTRMAGRMGGCNITVKNLEIIRIMPESNLLVVKGAIPGPKNSYVKIVSTKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CTK3_SCHPO
Sequence: MDPFEGRMTFLQLLGKLNASQFSQIKPAQFAIKHLDLEEDLYSCIWEELESGSFNTRVNIMYFVDTLCEMCLKNGLTGGYLNMISRDICKLVQNVAPIGAAGAANAPEVRKVLQSLHEKKVIDDNQYKDAMATVEAHEQASKSGDTSTSGAISKNDILKRIEEDRERHKRMRENIWAISEPELEAEIAWNTTQGITESDLESLKDEYEKFNECLHATS
What is the function of this protein?
Subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit.  As part of the CTDK-I complex, involved in RNA polymerase II transcriptional elongation and pre-mRNA 3'-end processing.  Together with ctk2, required for ctk1/lsk1 CTD kinase activation (By similarity).
What are the official names of this protein?
CTD kinase subunit gamma, CTDK-I gamma subunit, CTD kinase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CTK3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NAR5_BOVIN
Sequence: MIQATLLISLSCLSFYTLGSGVRRYDPGQGVTIQYLSLAPDTFDDAYVGCSEEMEEKAVLLLEKEMANHTRLRESWETAQKAWEQKRAGLTLPPGFRSQHGIAIMVYTNSSNTLYRELNQAVRTGGGSWESYMKHFPFKALHFYLTRALQLLRGGGGCSREPRQEVFRGVRRIHFVPKSVGDSIRLGQFASSSLDEAVACGFGSATFFSLRTCSGAPIQALSVFPEEREVLIPPYEVFVVSNFSKDGNKSLMTLSSSDQMCSHFNCAYLGEKKRPSCEFVPIGGQGDSLSKGAFSLLSWKTLLLASWGFQLLGAGL
What are the official names of this protein?
Ecto-ADP-ribosyltransferase 5, ADP-ribosyltransferase C2 and C3 toxin-like 5, ARTC5, Mono(ADP-ribosyl)transferase 5, NAD(P)(+)--arginine ADP-ribosyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Membrane-associated.
Protein: LOLB_PSEAE
Sequence: MRLRLFLAASALALLSGCAGLTSHEALEGQGDAQTWKTHKQQLSELDAWQIDGKVGIRAPRDSGSGTLFWLQRQGYYDIRLSGPLGRGAARLTGREGAVSLEVAGQGRYQAESPEALLEEQLGWRLPVSHLLWWVRGLPAPDSKSRLTLDADSRLARLEQDGWQIEYTRYAEQNGYWLPERLKLHGQDLDVTLVIKDWQPRQLGR
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NACB_BOTFB
Sequence: MDMEKLKRMQARGGVRTGDGKGTPRRKVKNVHKSTGMDDKKLQTSLKKLNVQPIQAIEEVNMFKSDGNVIHFAAPKVHAAVPSNTFAIYGNGEDKELTELVPGILNQLGPDSLASLRKLAESYQSMQKAEGGEDKKDDDEDDDDIPDLVEGENFEDKVE
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
What are the official names of this protein?
Nascent polypeptide-associated complex subunit beta, NAC-beta, Beta-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: NDK_CROS5
Sequence: MERTFIMIKPDGVQRGLVGEVIGRFEAKGFTLVGLKLMSVSKELAEEHYDVHKERPFFGSLVEFICSSPVVAMVWEGDGVVASARKLIGATNPLSAEPGTIRGDFGVSVGRNLIHGSDAIETAQREISLWFNEKELSSWEPTAKTWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH3_PYRNV
Sequence: MHGVVVVELKGYREWTESLGPRREHIIQQVQSRIQAAVWRSFTAVGALPHHFRYDFYIALVNGVSLDLVKRAVEKAARASPVGAGFCLGVGETPYEAYLRCGGGGGGAASPAVVAHMDVINSTEATRRNGPLDVYLKVVKLLGQLGERCKDLGCMAFYLGGDNIALFLPSPNAIYSILDGVDLRVRVGVGVAKRPYNAFVRATWALDRLRSAGREGVEVVK
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: RBL_PARP8
Sequence: MNDFSKEAVKPADSATAAAKAEKRSRYAAGVMKYREMGYWQPDYTPKDTDVIALFRITPQPGVEPEEAAAAVAGESSTATWTVVWTDRLTACDMYRAKAFRVEPVPNPAEGEPQYFAFIAYELDLFEEGSVANLTASIIGNVFGFKPLKALRLEDMRIPVAYLKTFQGPPTGIVVERERLDKYGRPLLGATVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMHWRDRYLFAMEAVHRAQAETGEVKGHYLNVTAGTMEDMYERAEFAKELGSCIVMIDLVIGWTAITSMGRWARKNDMILHLHRAGHGTYTRQRNHGISFRVIAKWLRMAGVDHAHAGTAVGKLDGDPLSVQGYYNVLRESHNSVDLTRGIFFDQHWAGLRKVMPVASGGIHAGQMHQLLDLFGDDAILQFGGGTIGHPSGIQAGATANRVALETMVKARNEGRDIANEGSDLLEAAARHCTPLKQALDTWGDVTFNYTPTDSPDFAVTPSVA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: LEUC_DESVV
Sequence: MAHTLAQKILQRHTDEAITDAGQIVRCRVSMVLANDITAPLAIKSFRAMGAKRVFDKDRVALVMDHFTPQKDIEAAQQVKLTREFAREMGVTHYYEGGDCGVEHALLPELGLVGPGDVVVGADSHTCTYGGLGAFATGLGSTDVAGAMALGETWFKVPPTIRATFTGTLPAYVGAKDLILTLIGAIGVDGALYRALEFDGAAIEALDVEGRMTMANMAIEAGGKAGLFAADAKTLTYCTAAGRTGDAAFSADAGAVYERELSFDVTGMTPVVACPHLPDNVKPVSEVKDVTVQQVVIGSCTNGRIGDLREAAAVLRGRKVSRDVRCIVLPATPGIWRQALREGLIETFMEAGCIVGPATCGPCLGGHMGILADGERAIATTNRNFKGRMGSLESEVYLSGPATAAASAVTGVITDPSTL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RPOZ_DEIRA
Sequence: MAEKDIDKLLSLTDSKYRLSVVTAKRALQLRSGAPSVLPVEQRVRTHNLVTQAMRELATGQLTVGTNLIDEQRFHQDYVRQRQAQLQAQLNAERERERD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL31_CLOBH
Sequence: MREGIHPEYNHDVVVKCACGNTFTTGSTNKELKVEICSKCHPFFTGKQKIVDAGGRVDKFMKKFNLSNEDVK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: YCXD_CYAPA
Sequence: MFYTLPKQLEINNLTVSYPHGTVLQNIFLTIESGKLIGIIGPNGAGKSTLLKTIIEQIKPISGEIFYQGAPLKNQRARIGYVPQRAQVDWDFPINVWDVVMMARLKKIGWFSSYSKKSYECVKAALEKVDMLKYKDRNIRELSGGQQQRVFLARLLAQEADLLLLDEPFTGVDFQTQKIIFSLLKEQIASNKIVIVIHHDLGESIINFDELILLNKKIISHDLTTKILNSKKLSTLFGEHIYAN
What are the official names of this protein?
Probable ABC transporter ATP-binding protein in ycf23-apcF intergenic region, ORF244.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: SYR_STRMK
Sequence: MKNLLRALISQGIEALRANGTLPADSLPPDFVVERPKTRDHGDFATNAAMLLAKAARSNPRALAQALVEALPRSEDVSKVEIAGPGFINFHLAPAAYQREAASVIKEAHDYGRNLSGNGRTVGVEYVSANPTGPLHVGHGRAAAIGDCVARVLDANGWNAKREFYYNDAGVQIENLALSTQARIKGIAPDQDGWPEGGYRGEYIADVARAYMAGASVDLEGSTVVGAKDPDDMQAIRRFAVAYLRNEQNLDLAAFGVDFDIYFLESSLYADGKVAEAVAKLQASGHTYEEGGALWLRSTDFGDDKDRVMRKSDGTFTYFVPDVAYHLSKWQRGYERAITELGADHHGSLARVRAGLQAMEVGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGSYFTLRDLIEEAGRDATRWFLIARKPDSQLTFDIDLARQQSNDNPVFYVQYAHARVCSLLRQAQEKGLVYEQGNGLANLGRLADDASLLLMNEISRYPEVVEAAGVALEPHLVAQYLRELAHAFHTWYHGTPVLVEDAADRNAKLTLACAARQVLANGLELLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_LEPBL
Sequence: MSKTFIMIKPDGVKNKHVGNILARIEKEGFKILGLKYLKLSLEDAKQFYKVHSARPFYSDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGTIRALYAESKEANAVHGSDSDENAALEVSFFFKGNELF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRY1_CHICK
Sequence: MKFLVLVAFVGVTVAFPISDEDDDKIVGGYSCARSAAPYQVSLNSGYHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDIMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGIGCAQKGYPGVYTKVCNYVSWIKTTMSSN
What are the official names of this protein?
Trypsin I-P1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MUTL_ACIC5
Sequence: MGRIRVLSDQVANQIAAGEVVDRPASVVKELLENAIDAEATRIRVEVEAGGRKLIRVTDNGIGMMRDDAMLAFERHATSKIRSSDDLLTIATLGFRGEALPSIASISRLEMITRAQGEETGTCIEIAGGKMLRVEDAGAPPGTSFTIRDLFYNTPARRKFLKAESTELSHVSALVTHYALAHPDKHFELHSATHALLNAPPVNEPSERVFQIFGAETLNQLIPMAAERPFDRAGLPEPPPWRRDQDYEPPDPGFLRVKGFISKPALQKLNRNSIYIFINRRLVRDRLILHAITEGYRNIIPPTSFPVALLFLEMPPHEVDVNVHPAKTEVRFRQSSVLHDFLRDSIRNALMKARPAADFLAALSASEPVSSVLPTATPVQDSEVIPAGSEAAGEVAAFALTEPVLPSVEQPLPFARAEMTVPQVQGAAGSAPAPPAYPAVAGAAARVPGGNCGHDAGPEEIPPPGGEAGTLASLASLKPLGQLRESFILAVNDEGFWIIDQHVAHERVLFEKILREREVERVHRQRLLMPLLLDLLPHQMVRFAEIAQELERNGFEAEPFGPHTIAIKASPVGLEGARLERMLVEVLEQTGTGTQSENLETVRTRIAASIACHSAIKINTPLDPQRMEWLLAELARTAHPTSCPHGRPIALRYSWKDIQRAFERI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: THIQ_SHIF8
Sequence: MLKLTDITWLYHYLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTEELLSGKASASAILGITG
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS11_SODGM
Sequence: MAKAPIRARKRVKKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCAEAVKEYGIKNLEVVVKGPGPGRESTVRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ENGB_ACIC5
Sequence: MQVYPKFMRSAMATEHFPPVTAPEFAFLGRSNVGKSSLINALLGSKQAKVSSTPGRTRAINFFSLTTSPERQQPNFLFADLPGYGYAKISKSISAEWPKFIEPYLAERPSLALCLCLVDSNIPPQPSDAQLTEFLRSIGRPYLVVATKADRLSGNGRTKAKQTLSRALEAENLLLCSAKTGLGMKELWGEIHRVAAEATEAMKQNQRPPSA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YGZ2_YEAST
Sequence: MNTEGASLSEQLLDAARRNNLDLLETVFDSLDNDPEKIAKLINESKEPLGNTALHLCCKYGSWEVLDKILDQDGEIEIDPQNDVDGDTPLHVTVRYSQEEPEHGTFIARNLIEVGADPRVRNYNNQKPVDLVHGDELDELIDLLQGAELAIDSTNGSGDNNEDGEMIDDGPSDDDEEDDKK
What are the official names of this protein?
Ankyrin repeat-containing protein YGL242C.
Protein: CCL17_CANLF
Sequence: MIPLKMLLLVTLLLGASLQVTHAARGTNVGRECCLEYFKGAIPISRLTRWYKTSGECPKDAIVFVTVQGKSICSDPKDKRVKKAVRYLQRTWKGGPQES
What is the function of this protein?
Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes.  Therefore plays an important role in a wide range of inflammatory and immunological processes.  Acts by binding to CCR4 at T-cell surface.  Mediates GM-CSF/CSF2-driven pain and inflammation (By similarity).  In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.  May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation.  Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity).
What are the official names of this protein?
C-C motif chemokine 17, CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAE_PORGI
Sequence: MITIGITGGIGSGKSVVSRILLTLGIPVYDSDSRAKWLNDHSPVVRQALTGLIGSDLYENGILRRDRLAAAIFSSGDLLEQVNGIIHPEVKKDFCQWRSECESDLCAIESAILFSSGFNSLCDTVIRVDAPEKIRQERAMARDGSSAETMRQRMLSQEREQSLAKAGADHTVLNAPPHLLVPQVVRIIETVRTKRPNPPDRL
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BURCJ
Sequence: MELKLLNENGQEGAVVNASDVVFGRDYNEALIHQVVIAYQANARQGNRAQKDREQVKHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPEENFSHKVNKKMHRAGLCSIFSQLAREGRLSVVEDIILEAPKTKLLADKFKTMGLDSVLIITDTVDENLYLASRNLPHVAIVEPRYADPLSLIYFKKVLVTKAAVAQIEELLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.