PharMolix/UniProtQA huggingface dataset:
Protein: AMY_TITSE
Sequence: KYYEPNTVQGRSVIVHLFEWRWKDVADECEQFLSPKGY
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBS1_PEA
Sequence: NTDITSNGERVKCMQVWPPIGKKKFETLSYLPPLTRDQLLKEVEYLLRKGWVPCLEFELLKGFVYGEHNKSPRYYDGRYWTMWKLPMFGTTDPAQVVKEVDEVVAAYPEAFVRVIGFNNVRQVQCISFIAHTPESY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1, PSSU1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NP_ADE40
Sequence: MSILISPDNNTGWGLCSAGMYGGAKRRSSQHPVRVRGHYRAPWGAYTRGVISRRTTVDDVIDSVVADAQRYTRPVATSTVDSVIDSVVANARRYAQRKRRLQRRRRRPTAAMTAARAVLRRAQRIGRRAMRRAAASASAGRARRQAARQAAAAIASMAQPRRGNIYWVRDASGVRVPVRSRPPRS
What is the function of this protein?
Plays a role in the inhibition of host immune response within the nucleus.  Interacts with cellular nucleosomes and immobilizes the host immune danger signal HMGB1 on chromatin.  In turn, prevents HMGB1 release out of the cell and thus decreases inflammation.  Also plays a role in the wrapping and condensation of the viral DNA.  May also promote viral genome import into the nucleus.
What are the official names of this protein?
Pre-histone-like nucleoprotein, Pre-core protein VII, pVII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae histone-like nucleoprotein family.
What are the subcellular locations of this protein?
[Histone-like nucleoprotein]: Virion. Note=Located inside the capsid in association with the viral DNA (core). Present in about 1070 copies per virion. SUBCELLULAR LOCATION: [Pre-histone-like nucleoprotein]: Host nucleus, host nucleolus.
Protein: NUSB_HELPY
Sequence: MATRTQARGAVVELLYAFESGNEEIKKIASSMLEEKKIKNNQLAFALSLFNGVLEKINEIDALIEPHLKDWDFKRLGSMEKAILRLGAYEIGFTPTQNPIIINECIELGKLYAEPNTPKFLNAILDSLSKKLTQKPLN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PSBZ_GOSBA
Sequence: MTIAFQLAVFALIATSSILLISVPVVFASPDGWLSNKNIVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: DI3L1_XENLA
Sequence: MLKTEKILHLKTQRGRSVRAVREHYLREDVRCGSALCHTCPRDGKLLSEELTHYVVPDCQVLQDYQEVLEFPELRGIIIMQTACQAVQHQRGRRQYKKLCSLLRDTRHDCILFSNEFQNHAYLPREMGESALAWQTRCIYNSCVWYYQHCQKKIPVVMVTEDESVIGKYNTETQEVYVVSFQIYLETFWPNFKGALELYKSLRDTHLERKLESRESNGKEYPEHLPLEILEAGIKSGRYKQGVLSVNKHRAQLESFVRLQGLGGKETDIQSDIFIHGTKPRNRAIHGDLVAVELLPKSEWKGRTGALCENETDEKVGDMQAEVMPTGRVVGIMQRNWRDYVVTFPAKEDTETQGKNTQKVLVMPWDYRIPKIRISTQQAEALQNYRVVVRIDSWESNSLYPNGHFVRALGRAGNLEAEIATILVENSISLNPFSEAQLAEMPSNTHENPWQVKPEEGDRLDLRETHLVFSIDPKGCEDVDDALSIRVLPSGDLELGVHIADVTHFVQHNTYTDIEARSRATTYYLADRRNDMLPLILSADLCSLLGAVDRYAVSVIWEMDCSTYEIRRVWYGRTIIRSSYKLSYEVAQQLLDGDLEPLSTEKELHPLKQDPARLQQLLWAVGKMTEVAHATRMRRNMSGALELEGVEVRVQLGEKHSIDDLVPKQPLQVHETIAECMILANHWVAKKIWESYPQHALLRLHPPPRQEFFQELKECAKARGFSIDTRSNKALADSLDQAHDPSDPLVNQLLRMMATQAMSNARYFSTGSYTEDEFYHYGLALEKYTHFTSPIRRYADIVVHRLLLAAVNKGPKDHLLGNKDLEELCRHINARNRAAQQCQKQSTELFQCMFFKDKDPDSDQRCISDAVIYGIRTNGVLLFIPRYGIKGAAYLKNTDGLVLACEEDGQCRWVHGSLQRLPAQIVVTTQEAKSFSFCLFDHVTVRIRIQSSRFHPDSIRLEIISNRPNPSQEALPSASNPQLLRTELVKEVTRTAVEAQLAVEGAAELKPVERYQEYRQTQGQSLYTMLEELWDLALLDVSGA
What is the function of this protein?
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
What are the official names of this protein?
DIS3-like exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBX12_DICDI
Sequence: MTSTANNNTSFYCNNNNSNNNININCCSNTGHNGNNTTETTLTTVNEERCAPTPTPTSTPPHGSALNIQNSNNGCNNIIGSSSNTLSTPSVQATPPTPPPSSSSLLVQPMIVTPSPVVATTSSLITNDDNLNSSTNYLMLPHQAQSSAMTIVQPPPPSTPLSSSSTVVPASTPPPSVMTPITTIQTTATPPSLQPTIHHQTALSFLGYTYNEQYQQNICQLYHQLNANGNGNGNGNGNHNNNNNNYNYNNNSFYQHQQHQHGLYYNQFPIPMNSSVPIIPTQQYIGTKQPQSQSQSQQLQPQPQPQPQLQPQLQSQPQSQQLKRKEASYHNNNNNNNNNNNNNNNNNNNNNNPYNRPTKKIMVSQGLPPISSSPSFQNLNNKYFDFNQPITRNNYNQVNYNNNNNNNNNNNNNYNNISNNNPCNNNNNNKPNNNPNNNNSNSNKTYINKQHRDYGYENNNNNNNKTFQQTSQQQQQQQQQIYKKQNCNNYIDESGDDESGEEYQNYQPYQQYQNFKQNNKDNNNNDDDDDDDDDEEEEEEEEDDNDNCNGNDSYDEENNNNNNNNNNNNQFKNESIIIGDNYYEIINDRIKSIKQKLHFLEKNSKFQWIREKSFNFINEFTGESVVNEELGIRGSKDFSYLKYKTLNPSLDNYITQERIELKNPLIKANIEKLKKDFNFEITKINTTKSESLEIMKSIQQLSTTVRSPLLDRSDLKAQRNHIHGFFTLIIAHQKCLSFDFIYQMRPQSMDHQHGFSNTFTDDFTNGGGCSISDKKNRRTLNDQYKSFISDYFKNHSDHPYPNEDEKIIISALIDLSKYQRNNWFSNKRSREKNQRIVNLKKQIGFH
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Homeobox protein 12, DdHbx-12.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTG_AERS4
Sequence: MDKFSLSHMSVWQGRQDPEDGELALRWYDKVQAWPLSGTAEPGVALVGFACDEGVRRNKGRVGAAGAPLAIRKLLANSAWHLTRPVYDSGDLTCDDGDLDAAHARLAERVASLLDEGHFPLVLGGGHEVAFGSWNGLNRHLVGQGRVGIINFDAHFDLRRKVEQASSGTPFFQIAEQCTAQGTPFHYACLGVAETANTQALFARADALGVWYVKDEAMSERSLPALLSGLDSFIAQSDHIYLTIDLDVLPGAVMPGVSAPAARGVELAIIEPLIAHIQASGKLRLADLAEYNPNLDQDNRSARVAARLVHQLTK
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: CSRA_THEMA
Sequence: MLVLTRRVGEKIVIGEDIVITVLKIEGNSVKIGIEAPKHVKILREELYEELKSENIKASEVSKDDLKGVLRNDKGYKGPSASS
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLRBF_RAT
Sequence: MDTSRVYGNVKTFRSPGHKQASFPSLSTDACRCPHWHHLALKLGCATLILLLLTLIGLSVFVRFLVQKPLIEKCSMAAQENGTEPTGRSAILECPRHWQPHRNKCLIISQISRPWAEGLVACSMKEATLLIIENEEELKFVQNILKGRQQLFFIGLNYVQTEMTWKWINGSVLKPNILRITGSEVENSCALISHTEVFSDSCSSDNHWICQKTLKHV
What is the function of this protein?
Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation.  May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity).
What are the official names of this protein?
Killer cell lectin-like receptor subfamily B member 1F, Natural killer cell surface protein NKR-P1F.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SYI_CLOTE
Sequence: MYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPTANGKPHVGHVLTRVIKDLIPRYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIEKFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYVTYHNDYIESVWWALKQLWNKELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWTLPSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLLPFYTPEEEAFRVIHGDFVTLSDGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFIDCVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHCWRCDTALLYYPTDSWFVRMTSLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECIGSISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHHYPFENKEVFEKTFPAQFISEAVDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGLKMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRFSPEDVEETQRKFLSTLWNVYSFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDFVDELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVRGLDKNALESIHLCNWPKYDENLIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSMLVSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPNLPVLGKAYGRYIPQIRKEITSMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTITDELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEEVIYNEEREYVDCKINGEDFKIEVEAIK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_CYAP4
Sequence: MARSGYTLPVFACAAAIAALQHLKNLQAELDPIEGPLHSVTLDLINPPQTVEIAIEQVAKLGPGTALAISRSDPGDNLDITRNTPIWAVVTWAEDQQLDSIVIEGGEGIGRLSSTNDRAAIYAYAQHLLQTNLQKLLNSTEKIRVTIILPEGRSLAQRTSNAAFGIVDGLSLLGTSGISQPLSAPEQLEQFQTQLQQKAEQRKHLVFCLGENGLDLAQKLGIDTACLIKTANWIGPMLVAASLEGVEGILLLGYHGKLIKLAGGIFHTHHYVADARQEILTAYAATLGLPQTDLNVVFNSPTTEAALQHLRHLDQTTGSQWVAQIYTELVRQIDQRSQTYIQSQTNHRVIIGSILFDQQRQIIVSSPGGTALREQVTMA
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: NUOI_LEPBJ
Sequence: MGTVNVVRVVSLHKLSWYEKFYFYSIGKGLWITLKHFIKAAILRRTVTIEYPEKKRKYSTRFRGMHTMKRDEQGRERCTSCFCCMWICPADAIYIEAGEVVPEIQHLHPEDKYAKKFEIDLLRCIFCGMCEEACPKGAIYLDGPGEMATDSREDLILTKERMMQIVGGPIIGERQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPC_FRASN
Sequence: MNALEEILDGVRADLAVRERETSLAALKQRVERVPDPRDALAVLRAPRVSVIAEIKRRSPSRGALATIADPAALASLYEQAGAAAVSVLTEQRRFGGSLADLDAVRVAVDIPVLRKDFVISPYQVLEARAHGADMVLLIVAALDQPRLIGLLERVESLGMTALVEVHDETEMLRALDAGARLVGVNARNLRTLEVDRETFARLAPMVPQGVLKVAESGVRGPRDLLQYAGAGADAVLVGEAAVTGGDPRQFVADLVTAGTHPATRIAH
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ATRN_HUMAN
Sequence: MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI
What is the function of this protein?
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines.  May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color.  Low-affinity receptor for agouti (By similarity).  Has a critical role in normal myelination in the central nervous system (By similarity).
What are the official names of this protein?
Attractin, DPPT-L, Mahogany homolog.
Protein: NRDR_HALOH
Sequence: MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREFFDRNKLLTGIMKSCEKRPIPQEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDIDEVAYVRFASVYRQFKDVNKFKQELERLLQED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: S14L4_MOUSE
Sequence: MRGQVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQILTWQAPEVIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKRYYLSNQERPQYEHSVVVGRGSSHQVENEILFPGCVLRWQFASDGGDIGFGVFLKTRMGERQKAGEMVEVLPSQRYNAHMVPEDGSLNCLKAGVYVLRFDNTYSLLHTKKVGYTAEVLLPDKACEEKLQGLGSVSPP
What is the function of this protein?
Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
What are the official names of this protein?
SEC14-like protein 4.
Protein: PSTB1_SHEON
Sequence: MISIDSTAMKTNSFDLANLSQDDTALEIRNLDLRYGDKQALFNVSMKIPKKQVTAFIGPSGCGKSTLLRCINRMNDLVDNCHIDGEILLHGQNIYDKRIDVAALRRNVGMVFQRPNPFPKSIYENVVYGLRLQGINNRRELDEAAERSLRGAAIWDEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELITELKTKYTVVIVTHNMQQAARVSDQTAFMYMGELVEYADTNTIFTTPKKRKTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURC_VESOH
Sequence: MKDLRMVFKSRITNIHFVGIAGSGMSGIAEVLHNLGYGVSGSDISQNKITDRLKEMGCQIYYKHHQDNIKNAQAVVISSAIKDNNPEVIKAHQLNIPIVPRAEMLAELMRFRFGIAIAGTHGKTTTTSIITHILNMAELDPTYIIGGILNSSGINAKLGESDYLIAEADESDASFLHLQSMLSVITNIDHEHMATYNNDYQKLKDAFVSFSANLPFYGTCIICIDDKGVNEILSDIHRPIITYGFNNGADIQAINIKQVDMQMHFDIIYDKYTKPFPIKLNLIGKHNILNTLAAIGICCELNIKVNIIQKALANFSGVARRLDYHGKLNINNLQISLFDDYGHHPKEISAVFESLKDTYQNKRLVVIFQPHRYSRTHDLFDNFTRILSTADALILLDIYPAQEKPIAHINSSTLADAIRKYSSLNPVVIKNQKKILDILPNIVHNNDVLLTLGAGDIHTLPELLKFNYT
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_ZYGCR
Sequence: MLITKADPMVVSMGPHHPSMHGVLRLIVTLDGENVADCEPVLGYLHRGMEKIAESRTTLQYLPYVTRWDYLATMFTEAITVNAPERLANIQVPKRASYIRMIMLELSRIASHLLWLGPFMADIGAQTPFFYILREREMIYDLFEAATGMRMMHNYFRIGGVAVDLPYGWVDKCLDFCDYFLPKVNEYERLITRNPIFLKRVEGIGVIGREEAINWGLSGPMLRASGVQWDLRKVDRYECYHELDWQVEWQSGGDCFARYLVRIGEMRESVTIIQQALKAIPGGPYENLEARRMASMAQKNSQWNDFEYQFVSKKPSPTFKLPKQEHYVRVEAPKGELGVFLIGDDSMFPWRWKIRPPGFINLQILPQLLIGMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MIAB_RHIEC
Sequence: MTQDSALLKAPEQTLRDGSNSRKVFIKTYGCQMNVYDSTRMSDALARDGYEPTEDMEEADLVLLNTCHIREKAAEKVYSALGRLREMKKKKAADGREMMIGVAGCVAQAEGEEILRRAPAVDVVIGPQTYHRLPEALRRAKEGQRVVDTEYAIEDKFEHLPVAESRKIRARGVTAFLTVQEGCDKFCTFCVVPYTRGSEVSRPVSQIVEEAEKLVEGGVREITLLGQNVNAWHGAGPRGEAWSLGDLLYRLAEIPGLARLRYTTSHPRDMDDRLIAAHRDLRALMPYLHLPVQSGSDRILKAMNRRHTAAEYLSLIERIRAVRPDIALSGDFITGFPGETDKDFEDTLRLVEEVRYAQAFSFKYSTRPGTPGAELKDQVPEEIKAERLERLQALLLKQQQEFAESCIGKEIDLLLEKPGRMPGQLIGRSPWLQSVNVDAKASQIGDIIKVRITGTGTNSLFAERAEAAV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAM_LAMBD
Sequence: MDINTETEIKQKHSLTPFPVFLISPAFRGRYFHSYFRSSAMNAYYIQDRLEAQSWARHYQQLAREEKEAELADDMEKGLPQHLFESLCIDHLQRHGASKKSITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV
What is the function of this protein?
Both GamL and GamS bind to host RecBCD nuclease and inhibit its activities, protecting the viral DNA against RecBCD mediated degradation (PubMed:2943636, PubMed:4275917, PubMed:126236, PubMed:1653221, PubMed:17544443).  Isoform GamS mimics DNA, preventing RecBCD from binding DNA (PubMed:17544443, PubMed:28009252).  Expression of this protein in E. coli renders cells more sensitive to fluoroquinolone antibiotics (which inhibit topoisomerases and induce dsDNA breaks) (PubMed:28009252).  Frameshift mutations that delete most of this protein (starting from position 78 or 97 of GamL) allow the bacteriophage to overcome the retron Ec48 bacteriophage defense system.  Overexpression of the wild-type gam protein in E. coli with an intact Ec48 retron leads to a dramatic decrease in cell growth, the frameshift mutants do not have this effect (PubMed:33157039).
What are the official names of this protein?
Host-nuclease inhibitor protein gam.
Protein: CMA1_CANLF
Sequence: MHCLPLTLLLLLLCSRAEAEEIIGGTESKPHSRPYMAHLEILTLRNHLASCGGFLIRRNFVLTAAHCAGRFIMVTLGAHNIQKKEDTWQKLEVIKQFPHPKYDDLTLRHDIMLLKLKEKANLTLAVGTLPLSPQFNFVPPGRMCRVAGWGKRQVNGSGSDTLQEVKLRLMDPQACRHYMAFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGQNDAKPPAVFTRISHYRPWINKVLKQNKA
What is the function of this protein?
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
What are the official names of this protein?
Chymase, Alpha-chymase, Mast cell protease I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Mast cell granules.
Protein: RPOA_TROWT
Sequence: MLIAHRPTLIEKKVSDIRSRFIIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSINIQGVMHEFSTIPGVKEDVTEIVLNVKRLVISSEIDEPFTVRLYKTGEGEVLAKDIEVPTGIEIGNGDLVIATLAKDAVFDMQLTIERGRGYVSAEQNRNDGMSLAGHIPVDSIYSPVHKVTYRVEATRAGERTDFDRLIIDVETKPSILPRDAVASAGKTLCELFGLARELNSQAEGVEFGVDSMIPESDEDLRIPIEDLGLSVRSYNCLKREGVNYVSELLGFSEQELLDIRNFGQKSADEVQEKLAELGHSLKGSVPGFDGSYFDPNYGS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TRUD_PYRHO
Sequence: MLEDPLRNLRYLTSSPGIGGKIKVYPEDFIVKEVIPKSIFRGGRCRIYLLKKKNWETMAAIKEIAKRIGIHYSEIGFAGTKDRHAVTYQYISICREVDLENVAIKDVTLRFVGYGRPLKLGLLLGNFFKIRVRDTTPELLPNILKEAKEKGGFPNYFGIQRFGEKRSVNHIVGKLLLLGKYEEAAEVFLGYPGNGMEGDEARKKFLETKNVDLALEEFPKFLRYERAMLYKYRETGSWKRSFLALPRPILRIFIHAFQSYLFNLYISRRIEEGFPLNEALPGDIVVQVKKGIPLRDRTYRVTESNLDFVNEKIMQGEAMVSGPIFGYSYRRSHGIPGRLEDEILEEAGVSLENFKRLPKPMREPGGRRELLIKPRGFRYKTEGRDVLFKFFLPKGVYATSVLREIIKPT
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RISB_SPHAL
Sequence: MAHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDAYVALGVVIRGETYHFEVVSNESARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDKGGEAAKAALAMLALKEQFGIG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.