PharMolix/UniProtQA huggingface dataset:
Protein: AA2DA_DANRE
Sequence: MSVTPTANSTEEAANITASPRLWPYTEPASAIIILVVSLIILLTIVGNVLVIVAVLTSRALRAPQNLFLVSLACADILVATLVIPFSLANEIMGYWYFGSTWCAFYLALDVLFCTSSIVHLCAISLDRYWSVTKAVRYNLKRTPRRIKCMIAVVWLISAVISFPPLIMTKHDEKECLINDETWYILSSCAVSFFAPGLIMITVYCKIYRVAKQRSSTVFVAKNGLERQPSQSETCFVRKDKFEKESPSSNSSESAQRQEELDDIDLEESAASDSRARGSRFSKRRRVEGERRGPQRSCRVSWAAHQEPGSRQQQLASKSKVAQMREKRFTFVLAVVMGVFVLCWFPFFFTYSLQAVCGERCGPPEALFKLFFWIGYCNSSVNPIIYTIFNRDFRKAFKKVVCWSAQRT
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.  The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine > oxymetazoline.
What are the official names of this protein?
Alpha-2Da adrenergic receptor, Alpha-2Da adrenoceptor, Alpha(2Da)AR, Alpha-2Da adrenoreceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2D sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 228L_IIV6
Sequence: MWSIPKFGNEKNTFVDLSSSYSFKTPISNEERRRMGCQNPTFPFQEKISTREILIEPIQFGKFSISSEKLKNKYEGMLQLSCILSQDDVMEFAEELFENKSCTVLFNLKVLGLHAFFKMDEENLKRKLKNLDQNETDLAFIFIILLYALIEEDIKSSNDIYSLILQHSRNNKLISYIIRLIQAYENKEIGYDFFGINPSYLECFAMAIHIFISHNDNPQKVVDQALRFDKSVLRFLTWMLGASYGSNWIPQEWLKFSPNITNLIEKFLK
What are the official names of this protein?
Uncharacterized protein 228L.
Protein: MOAA_MANSM
Sequence: MQSIPIKNVGTNRLVDTFQREYYYLRLSVTDVCNFKCTYCLPSGYQPPVQKESFLSLDEIRRIVGAFAAMGTEKVRLTGGEPTLRKDFLAIVETISALEGIKKVALTTNGYRMEKDVERWKKAGVSSINVSVDSLDPRQFYSITGENKFHQVMKGIERAFEIGYEKIKVNSVLMKNLNDQEFDRFKNWVKDKPIQMRFIELMQTGEMDQFFNRYHLSGQILAEKLLKEGWILRQKDRTDGPAKVFSHPDYLGEIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFGEEGVDLRDLLVSDEQQVILQSRLYAALQGKREHHLLAQGNSGIRTNLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PELO_SULIA
Sequence: MRILEFDEKRQAAKLHIESEDDLWILHLILEKGDKVVAKTTRDIGLGKESRRIPMTIVLKVDYTEFQEFTNRLRIHGIIEDAPERFGIRGAHHTINLDIGDEIIIIKQQWSKYALDKLKKQADKRSKIIIALVDFDEYLIAIPFEQGIKILSEKSLRSLNEEEGIIEQNALEVATELAEYVKQYNPDAILLAGPGFFKEEVAKKVNNILKNKKVYIDSVSSATRAGLHEILKRDIIDKIMSDYEIAIGAKKMEKAMELLAKQPELVTYGLEQVKNAVEMGAVETVLLIEDLLSSNNQERLAIERILGDIENKRGEIILVPKESPIYFELKNLTGILAILRFRIN
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2388_CLOB1
Sequence: MAIKLINIGFGNIVSANRLVAIVSPESAPIKRIIQEARDRGMLIDATYGRRTRAVIITDSDHVILSAVQPETVAHRLASKAEEEDINEGEE
What are the official names of this protein?
Putative regulatory protein CLB_2388.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: PRCA_NOSS1
Sequence: MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTRFSQAGVEVLHVKEPSQDGALRDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKFGHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTGLAIFDIAERLLNEESVELCHPELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDHEEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAACNDFGTRSAYSDFGQAVWCAFPSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPVSIFTAVQDVPINDLQTSQLSLAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLPIILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADTGKIRSLTIELGF
What is the function of this protein?
Degrades phycobiliproteins in vitro.  Has a substrate specificity similar to that of trypsin (By similarity).
What are the official names of this protein?
Calcium-dependent protease, Trypsin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_ACIAD
Sequence: MKHIVIPARFSSTRLPGKPLLEIHGRAMILRVVDQAKKVQGFDDLCVATDNERIMQLCQAEGVDVVLTSPDHPSGTDRLSEVARLKGWSEDDIIVNVQGDEPLLPATLVQQVAELLVAKPNCSMSTLCEPIHTLDEFQRDSIVKVVMSQYQEALYFSRATIPYDRDAAQTQQSSRFEHAYRHLGLYAYRVGLLQEYVAWQQGVLEKLESLEQLRVLENGHRIAIALAEVNLPPGVDTPADLERLNALPRSYFE
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK1_STAHJ
Sequence: MQTQLGENDISLPQYYNNRELSWLDFNYRVLQEAYDKNNPLLEKLNFISIFSSNLDEFFMVRVAGLKDQVKMGYDKPENKAQMTPQEQVDAIQEKAKKYVDTQYERYNELMIELKDYEIVMCEPHELSEPLLSKLERDFKLTILPTLTPLGIDAYHPFPKLNNKSLNIFVDIDTEDAINSAIVQIPSLIPRFLTYNEGAKQYVVMVEDVITYFINYLFTGYEVLNTFTFRITRNADLTIHEDGAEDLLIEIERFLKERKSGSAVRLEVDGRTENPDDLDWLIETLEVDKQDVYFLNGPLDLTFIFGLVDHLSHKLNYLTYEKYSPQIPRSLGNNNLYELALKRDIFFHHPYESFEPIVDFIREAADDPNTIAIKQTLYRVSKDSPIIKSLKEAAEKGKQVTVLVELKARFDEENNVHWARMLEDAGCHVIYGMTHLKTHSKIALVVKRIGGELTSFVHLGTGNYNDKTAKLYTDMGIITTNEQIAEDAINFFNYLSGYSVKPEYNKLIVAPFDIRDVFIDRIDKEISSHLQHGNGKIMMKMNSLTDKAIIEKLFEASQAGVKIQLIIRGICCLKPGIPGISENIEVVSIVGRLLEHSRIYYFHNNGDERIYLSSADVMTRNMIKRVEILFPVEDKEIGKRLVDFMDLQLSDNQKGRYQDEHGHYHYVENNLSPLNSQVYLMQEAIKYGQELKKRSAQPSGMPVVSKRRANWMNRIRRSLKK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: EP2A2_HUMAN
Sequence: MHPKEGAEQHVFSPVPGAPTPPPNRCGRLVLGPRLPAAGTPGPGIRAAAARHALPLWGGGATRRGRRPAGAAGGGVAARAGALGAARCRPPEAGRHRGGRRGPGPAGAGPVARGGGAGGRGGGAGRGGAGPRGHVLVQVPEAGAGRRALLGRYCQQTPAPGAERELRPAPPTGASASGRPRRPRRRASRAFCPRPCALPGRPGLTLLCRPRCRRQPRLRLPTDSLDPYSAPGRLPAHSVACPSDLVSAHPVLSFFPTAPASRASALRLPPGAPFALRVPLDLRVPPFAGPLAARPRAADGFNSPTPPWLGFVSSFSCSNSLKKTQNDPTNETSVFANPRQQCAT
What are the official names of this protein?
Laforin, isoform 9.
Protein: SYK_ERWT9
Sequence: MSEQQPQAPDAALELNNELKARREKLVALRATGLAFPNDFRRDRTSDQLHAEFDGKENEELEALGIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVSRDDLAEGIYNEQFKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGLADQETRYRQRYLDLIANDDSRNTFKIRSQIMAGIRSFMVDRDFMEVETPMMQAIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFDRVFEINRNFRNEGISPRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDVLGSTVVPYGDQQFDFGKPFEKLTMKEAILKYRPQTDLADLADFDKSVAIAQSLGIKVEKSWGLGRLVTEIFEETAEAHLIQPTFITEYPAEVSPLARRNDMDPEITDRFEFFIGGREIGNGFSELNDAQDQAERFLQQVNAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPALRPGSK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH21B_XENLA
Sequence: MATRRAIVPEQQQEPSSPASEISKNKDWQEQSEMVSPTEEEGFCWPGPKSVALRRASEGFGFTLRHFIVYPPESAVHTSVKDEENGNRGVNAGRPRNRLEPMDTIFVKQVKEGGPAHEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSVMPKDEDILQLAYSQDAYLKGNDSYSGNAQNIPEPPPLCYPRVQPEASVMAQPVEVLPSGTSLATQQSSCPLRTATTQPERSYRVEIQVPPSPTDIVKSNTAVCVCNEAVRTVIVPSEKVVDLSSNRTNRAGPLHRTGLADPSILKRTTSPSSSTPNVPMVPSTRHFDSAGVIGKPPSYGGLAENMFSTRPAAHAEESPSPTNHYASPGSHQHIDWRDYKTYKEYIDNRRMLMYGCRTIQERLDSLRAASQNTTDYNQMLPNRSSGQVRRRSTSHDRVPQSAQMRKRSVSQERLEDPVLMKEWPRSASQDTLTSPAVASRNHRSELWDYLTRKGDFDQFIVETHSNGERNTNYQWSGFTEQDDRRGINERPRQHAFHMSLRSPNFTMAPVPFTSSDNRRGGARVLASAHPLQMVHPDMKTIQPTRNFQNSSRAPHPRPALSDRSGFAISKSNSVKIPTPYAAKPHSPSVRSDDGIVRDQKPVNYLHVGGPQNCQRKTQTESALGFHLDSIKTSMSASSSSPSTSQKVDVKITQSPEANAGDSNAVLSPVDQVVLRERPSPGQQTSPPIRQQSYIFAVNEQEGASDTTCWLPNDARREVHIKRIEQRKASGSNSPGDSLASIPFIDEPTSPSIDHEIGNIPASAVISISAQPLPTITTVPPSPTSPVPLMRRHFSHDHDSIRPIVLEVNSKTERSKSCDEGLDDYKEDGKLCLKQGSSLKGIKARENVQSSEDSESRKDSSSDVFSDSNKEGFLYFRQLTTEKGKRVSGSIRPWKQMYVVLRGSALYLQKDKKEQTGHSSAQSDEEQLIGINGCLIDISYSETKRKNVFRLTTSDREFLFQAEDRDDMLAWIKAIQENGNLNDEQTDQASRVLISKRIKEYNTMMSSSSNKTEPSPKAQRQTLSIRQQFRAGKPDDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGNTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDFIEANRKEDPVERLKTLKRLILDLPDHHYETLKYLSAHLKTVADSSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQKHDWFFSEESADEPITTVHEESTVESQPVPNIDHLLPNIGRTGLSPGDVSDSATSDSAKSKGSWGSGKDQYSRELLVSSLFAAASRKRKKQKDKPQPSSSEDELDNVFYQKELSQVEFQKPDKQNVDKDMDLKAKANALSLKDADNVKGTNIIKEDKLEKDIMYSEPTSPCPPKLLEPPIANHGLQAPSNDKNIPQINFQMEESMSDSGTMLSTSSQASVQGSKPKVVSPEFKGSDFLTADVSSITSDYSTTSSTIYMTGLDSILISPEVQSVAESKGEEADDERSELVSEGRPMETDSENDFPIFASSLAFDRRHQSKAEEPSRNVQVNSEGSPSCTEGSITPKMDRRRFSSHKLIECDTLSRKKSVQQKTDSDCSAESKTEETLSDAQEAVKKGRSLSIVDPTGNNEPEEPAWRIKITERLKLRLKASADDMFGIGSQKANAAETRKKKNIRRRHTLGGHRDFAEISVLNAWKINEPSSKEAELSAVDRLKPKCPSQDLSISEWLVRERLRTSTSELSTVEPEEKHISETTGQKESASASPPPSSPSQVSTAVLPAGSDSPSHETAPQPDDQMNGDSFQSKNKNNFSPAVDAHPHKLSGTQVVRSRFYQYL
What is the function of this protein?
GTPase-activating protein (GAP) for rhoa and cdc42.
What are the official names of this protein?
Rho GTPase-activating protein 21-B, Rho-type GTPase-activating protein 21-B, XrGAP.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: MSHR_MICAD
Sequence: MPMQGAQRKLLGSLNSTPTATSNLGLAANHTGAPCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSSMYCFICCLALSDLLVSGSNMLETAIILLLEAGTLATRASVVQQLHNTIDVLTCSSMLCSLCFLGAIAVDRYISIFYALRYHSIMTLPRAQRAIAAIWVTSVLSSTLFITYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIIRLHNRQLPAHKGFGLRGAATLTILLGIFFLCWGPFFLHLTLVVFCPQHLTCNCIFKNFKVFLTLIICNTIIDPLIYAFRSQELRRTLKEVLLCSWWPGCGAEGGGDSVWPGSCVTLRGPLPP
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGD_AMYMU
Sequence: MLKVGYKASAEQFGPRDLVEYAVRAEEVGLDSVWVSDHFLPWRHEGGHAPWALAWMPAVAERTKRVQIGTSVLTPTFRYNPAVIAQAFATMSLLSNGRVILGVGSGEALNEIAVSGREWPEFKERFARLRESIKLIRELWTSDNVNFKGDYYELVDAKIYDRPEQPVPVYIAAGGPVVAKYAGRAGDGFICTSGKGMELYTDKLMPAVKEGAEAAEKTVEDVDRTIEIKLSYDRDHEKALENTRFWAPLSLSAEQKHSVSSAEEMERLADELPIDQVAKRWIVASDPDEAVAQIKPYLDAGLNHLVFHGPGHDQERFLTQFSEDVLPKLRALG
What is the function of this protein?
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: ENTC1_STAAU
Sequence: MNKSRFISCVILIFALILVLFTPNVLAESQPDPTPDELHKASKFTGLMENMKVLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEGLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLIRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
What is the function of this protein?
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules.  In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (PubMed:2210803, PubMed:8039910).  Inhibits SEC1-mediated T-cell activation in the absence of MHC class II by competing with SEC1 for binding to the host TCR (PubMed:9498747).  Causes also the intoxication staphylococcal food poisoning syndrome (By similarity).
What are the official names of this protein?
Enterotoxin type C-1, SEC1.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RDGC_VIBVY
Sequence: MWFKNCMVYRVNREIEFNADQLEKQLAEFRYTPCGSQDKQKFGWVSAMGRHGDMMTHVSEDRILICAKKEEKMLPASVIKESLNTKVEAMEAQEGRPLKKKEKETLKEEIIIDLLPRAFSRSNHTYVLILPKEGFILVDASSYKKAEDVLALLRKTMGSLPVVPAIPEKAVETTLTEWVKTGQTPQGFHLLDEAELKSVLEDGGIIRCKKQELTSDEILSHIAADKVVTKLALNWQERLEFVLADDASIKRLKFSDELRDQNDDIPREDQAARFDADFSLMCGELSAFLPNLFQALGGLPHPNA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PPTA_ECO27
Sequence: MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISISLQQIQPESWQAIWDAEIAPQMEALIKKPGYSM
What are the official names of this protein?
Tautomerase PptA.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCI1_YEAST
Sequence: MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL
What is the function of this protein?
Peroxisomal di-isomerase that is involved in fatty acid metabolism enzyme by converting 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl-CoAs (PubMed:10381339, PubMed:10455114).  Required for ECI1 to be locazed to the peroxisome (PubMed:10381339, PubMed:11302517).
What are the official names of this protein?
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, Peroxisomal di-isomerase DCI1.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PUS1_KLULA
Sequence: MSEEQNLRPVYDDDQPGEDTYKRGAIYKQTRSRKADYEDGENSEKRQKPNDTDNGPTAVVTDLSNEKKETRSKDKDESVALAVDADGNPIPQEVRLPKRKVAVMIGYCGTGYHGMQYNPPNDTIEKELFEAFVRAGAISKANSTDLKKNGFQRAARTDKGVHAGGNVISLKLIIEDPEVKEKINNELPDQIRVWDISRVNKAFDCRKMCSSRWYEYLLPTYSLIGPKPSTYLYNEIEASKKEIPNVIQDDVESAQFWEAFSTEAESKFTKEELEEIAAFVMPKDSFDENNETYQKSKAFKKLEAEHKRAYRISKERLDRFRSALKQYEGTFNFHNFTLGKDFNDPSAKRFMKQITVSEPFVIGEAKTEWVSIKIHGQSFMLHQIRKMISMATLITRCFSPLERIRQAYGQEKINIPKAPALGLLLEAPVYDGYNTRLQEFGYDPIDFSKYQSEMDTFKMKHIYDKIYLEEVNENVFNAFFSYIDTFNPSYNISQEQQQLKGQELQQPSQAVELVTEDLEQKAPSDPTPSDEKGKKPQRPIFDFLTARGIQLQD
What is the function of this protein?
Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr).  Catalyzes pseudouridylation at position 44 in U2 snRNA.  Also catalyzes pseudouridylation of mRNAs.
What are the official names of this protein?
tRNA pseudouridine synthase 1, tRNA pseudouridylate synthase 1, tRNA-uridine isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GAL1_ECO57
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPI_NEUCR
Sequence: MLPVPLIQLQCGVNSYEWGKKGNSSRAAQFAAASLDDNEFKIDEEKPYAELWMGTHPSNPSKDKHTGRTLLELIQDNQALLSPAIAERYQNKLPFLFKVLSIQKALSIQAHPNKKLAEKLHARDPKNYPDDNHKPEMAIAISDFEGLCGFRPLKEIAHFLDNVPALRQLVGEDKAKAFVETVKRNDGNESDEATAENKKVLQSAFGALMASSEADMTAAADKLVQSAKSAGADFTGTAVPSPGGAKLSELVGRLHGQFGADYGLFVLFFLNFVEMKAGEAIYLRADDIHAYISGDIIECMASSDNVVRAGFTPKFKDVDNLVNMLTYDFAPIEQQKMEPTDYTQDVKNKREAGATLNQTAIDSQSEIVEYNPPIEEFSVVRSLLKSQGSKVTFKPIDGPSIIICTQGQGKISVGPKVQEIKKGHVFFVGATAECVLESEDDKFETFKAFCVLDEQSNGN
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLFB_STAA8
Sequence: MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQASEQSNDTTQSSKNNASADSEKNNMIETPQLNTTANDTSDISANTNSANVDSTTKPMSTQTSNTTTTEPASTNETPQPTAIKNQATAAKMQDQTVPQEANSQVDNKTTNDANSIATNSELKNSQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADAKGTNVNDKVTASNFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNSNNTMPIADIKSTNGDVVAKATYDILTKTYTFVFTDYVNNKENINGQFSLPLFTDRAKAPKSGTYDANINIADEMFNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQTVFVNPKQRVLGNTWVYIKGYQDKIEESSGKVSATDTKLRIFEVNDTSKLSDSYYADPNDSNLKEVTDQFKNRIYYEHPNVASIKFGDITKTYVVLVEGHYDNTGKNLKTQVIQENVDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPKDPTPGPPVDPEPSPDPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDSDSDSESDSDSESDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAPSNPKGEVNHSNKVSKQHKTDALPETGDKSENTNATLFGAMMALLGSLLLFRKRKQDHKEKA
What is the function of this protein?
Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps.  Partly responsible for mediating bacterial attachment to the highly keratinized squamous epithelial cells from the nasal cavity via an interaction with cytokeratin K10 (K10).  Also promotes bacterial attachment to cultured keratinocytes, possibly through an interaction with cytokeratin K10.  Binds mouse cytokeratin K10.  Activates human platelet aggregation.
What are the official names of this protein?
Clumping factor B, Fibrinogen receptor B, Fibrinogen-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Found in a ring-like distribution on the cell surface (PubMed:18800056). Colocalizes with SdrD (PubMed:18800056). Anchored to the cell wall by sortase A (Probable).
Protein: END4_SHISS
Sequence: MKYIGAHVSAAGGLANAAIRAVEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKFRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: T2D2_STREE
Sequence: MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIMNSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYSIEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLEAEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFYSGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNINDLEHNILKNLK
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3' and cleaves before G-1.
What are the official names of this protein?
Type II restriction enzyme DpnII, R.DpnII, Endonuclease DpnII, Type-2 restriction enzyme DpnII.
What is the protein family that this protein belongs to?
Belongs to the DpnII type II restriction endonuclease family.
Protein: GUAA_BRADU
Sequence: MGVQTCAVAGRGVVAYLLAMTAAQNDRSASTPSVASAHDKILIVDFGSQVTQLIARRVREDGVYCEIVPFNKAEEAFKEMKPKAVILSGGPESVHEAGSPRAPQLIFASGVPVMGICYGQMTMAAQLGGEVEGGHHREFGRADVEVKAQSKLFEDVWSSGSKNQVWMSHGDRITKMPPGFSVAGTSPNAPFAIIQDEKRKYYGLMFHPEVVHTPDGAKLIRNFVRKIAGLTGDWTMRAFREEEIAKIRAQVGKGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLMRLNEAEQVVDLFRHHYNIPLVHVDASKQFLGELEGVTDPETKRKTIGRLFIEVFEAEAKKIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRKLGRELGLPEIFVGRHPFPGPGLAIRCPGDITSDKLDILRKADAVYIDQIRKHGLYDDIWQAFAVLLPVKTVGVMGDGRTYDYVVGLRAVTSTDGMTADFYQFDMKFLGETATRIINEVKGVNRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NLTP1_CAEEL
Sequence: MAFKSDVIFEEIKERIATDKEMVKKVGTSFRMTIAGADGKTKVWTIDAKSDTPYVGDDSSRPVEIEINIKDSDFIAIAAGKMKPDQAFMQGKMKLKGNIAKAMKLRTILDPKMLKAKL
What are the official names of this protein?
Non-specific lipid-transfer protein-like 1, NSL-TP1.
Protein: ATPB_MAGTR
Sequence: MRINPTTSGPGVSTLEKKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQPINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RM16_ORYSJ
Sequence: MEKHLVMYLTRKSIMLLRKYPLVTEFQVSKCGSHIVKIRRDVLYPKRTKYSKYSKCRCSRGCEPDGTQLGFGRYGTKSCRAGRLSYRAIEAARRATIGQFHRAMSGQFRRNCKIWVRVLADLPITGKPAEVRMGRGKGNPTGWIARVSTGQIPFEMDGVSLSNARQAARLAAHKPCSSTKFVQWS
What are the official names of this protein?
60S ribosomal protein L16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Mitochondrion.