PharMolix/UniProtQA huggingface dataset:
Protein: PO5F1_BOVIN
Sequence: MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWMSFQGPPGGSGIGPGVVPGAEVWGLPPCPPPYDLCGGMAYCAPQVGVGPVPPGGLETPQPEGEAGAGVESNSEGASPDPCAAPAGAPKLDKEKLEPNPEESQDIKALQKDLEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLESMFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYSQREDFEAAGSPFTGGPVSSPLAPGPHFGTPGYGGPHFTTLYSSVPFPEGEVFPSVSVTALGSPMHAN
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').  Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.  Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity).
What are the official names of this protein?
POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding transcription factor 3, OTF-3.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus.
Protein: ACCD_STRS2
Sequence: MALFRKKDKYIRINPNRSRIESAPQAKPEVPDELFSKCPACKVILYKNDLGLEKTCQHCSYNFRITAQERRALTVDEGSFEELFTGIETTNPLDFPNYLEKLAATRQKTGLDEAVLTGKATIGGQPVALGIMDSHFIMASMGTVVGEKITRLFELAIEERLPVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTVLTDPTTGGVTASFAMEGDIILAEPQTLVGFAGRRVIESTVRENLPDDFQKAEFLQEHGFVDAIVKRQDLPATISRLLRMHGGVR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URM1_ANOGA
Sequence: MDDSIDEEVISGGSTITVEFSGGAETLFGGVKEHIVPLDGSKIVLLEEMLRWLRDHLLTGDAGLFLQENTVRPGILVMINDTDWDLMGETEYILQPGDHILFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_BARBK
Sequence: MHSAVEKVAEDLSLSRENLSLEEVEKAIRTLLLWVGENPDREGLLETPKRIAKVYKELFSGYGESVDEILGVVFEEVAGYDEPVIVKDIFFYSHCEHHMIPIIGKAHVAYLPDKKIVGLSKIARVVDVFAHRLQTQETMTAQVANSLKKYLKPRGLAVLIEAEHMCMAMRGVQKQGAATITTSFHGYYKKDQVAQANFMTITRGIR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CSPLJ_ORYSJ
Sequence: MASSSRTALPSAVLALRLLTLALLAASLAVIAADKLTLDFGGGLPPKKITFKDVYAYRYVLAIAVIGCAYTLLQIPFVAVSIAKRKRMIGGSENVALFLIFADVIFALLVATGAGAGFGLTYDAKSAFGGSKLPGEVVRFFNMAYAAAGLMLLAAAAMALIIMLSIYSLVR
What are the official names of this protein?
CASP-like protein 4D1, OsCASPL4D1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFGM_CRYNB
Sequence: MSAIARAAARVRQQNTTPLQRPLLLQRKPVLTHTLPLHASPLKPSLATSITSPNFQQSFQRRWASASAKAEEGAKEEVWPQRKLPELTETDKLRLRRQRNVGISAHIDSGKTTLTERVLYYTGRIRDIHEVRGRDAVGAKMDSMELEREKGITIQSAATFADWVAPKPPTELKEGETVGNTDKQKFAINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVSGVQSQTITVDRQMRRYNVPRLAFINKMDRAGSNPFRVIGQLRGKLKMNAAAVQVPIGSESDFAGVVDIVRMKAIYNEGVKGNQIVETDEIPESVRALAEEKRAELIEQLSEADETLCDLFLDEAPITPTDIAQALQRATTSLRFTPVFMGSAIKNTGVQPLLDGVCAYLPNPSEVQNQAMDATLPAHAPTIPLVPATDAPLVGLAFKLEEGRYGQLTYMRVYQGELKRGSMIYNARTGKRVKVPRLVRMHADEMEDVDAVVAGEICAMFGVECSSGDTFTDGSSTYTMTSMFVPEPVISLSIRPEGNETPNFSRALNRFQKEDPTFRVHVDSESQETIISGMGELHLDIYVERMKREYNVACVTGKPRVAFRETITEAAKFNYTHKKQSGGSGQFGRVIGSIEPMETDPDTGKDTAFENRIIGGNIPNQFIPAIQKGFQEALDRGLITGHPITGCKFVLDDGSAHAVDSNELAFRLAAIGAFREAFNKARPVVLEPVMTVEIVAPIEFQGNVIGAINQRKGTIVDTEVRDDEFTLTAEVALNDMFGYSSQLRGMTQGKGEFSMEYKNHQPVLPNIQKEMAEAFRKKQLSK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_RHIOR
Sequence: MKLLKSHPFLSLANSYVIDSPQPSNLNYAWNFGSLLALCLGIQIVTGVTLAMHYTPNIDLAFISVEHIMRDVNYGWMIRYLHANTASFFFLFVYLHIGRGLYYGSYKSPRALPWSIGVIILILMMATAFLGYVLPWGQMSLWGATVITNLLSAIPWIGKDLVEFIWGGFSVDNATLNRFFSLHYLLPFILAALAVMHLLALHEHGSSNPLGITANADRLYMHPYYTFKDLVTIFLFFLVLALFLFYAPNKLGHPDNYIPANPMQTPASIVPEWYLLPFYAILRSIPDKLGGVIAMFGSLLILLAMPLLDLSRVRGSAFRPLMKFFFWLLVVDFLILLWCGSQHVEEPFITLGQFATTFYFSWFLIIVPVVSVIENTLIDLATENKS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: G3PP_METTH
Sequence: MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDRHFNVLTKTVFGEEKPLLIALGMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGITIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEALRRMGCKPERSVMVGNKFNEDILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL
What is the function of this protein?
Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.
What are the official names of this protein?
Glyceraldehyde 3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: LAP1_TRIRU
Sequence: MKLLSVLALSATATSVLGASIPVDARAEKFLIELAPGETRWVTEEEKWELKRKGQDFFDITDEEVGFTAAVAQPAIAYPTSIRHANAVNAMIATLSKENMQRDLTKLSSFQTAYYKVDFGKQSATWLQEQVQAAINTAGANRYGAKVASFRHNFAQHSIIATIPGRSPEVVVVGAHQDSINQRSPMTGRAPGADDNGSGSVTILEALRGVLRDQTILQGKAANTIEFHWYAGEEAGLLGSQAIFANYKQTGKKVKGMLNQDMTGYIKGMVDKGLKVSFGIITDNVNANLTKFVRMVITKYCSIPTIDTRCGYACSDHASANRNGYPSAMVAESPIDLLDPHLHTDSDNISYLDFDHMIEHAKLIVGFVTELAK
What is the function of this protein?
Extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
Protein: AKTP2_DROER
Sequence: MWYSTESNPRIALIKQGYHILAEYNLVKEELKNIYAIPSYACALHWFGVIFVHSGIYAGSVFRFSILLPENFPDDVSLLTVVFSTGILHPHICPQNRTLDLEHFLKEWRKDQHHIWHVLRYIQAIFADPEGSICTGQSSSGDLVVMDEVRNMEALNMLAQSRPEYIKRVQEQAIASRNHIYDRPLTDDPHYIIVEPYCADRHLKIMDQLKSPCWKEATSMDCSQPSEYLGHIDSSRQLDEEEANQLEKLRRARIPEPHRDEAVDFL
What are the official names of this protein?
Protein crossbronx-like.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: C3H18_ORYSJ
Sequence: MAGEEGEDEAASIELQLEHHLQEQRASLTAVDEALAADPSNADLLEVHEELLAAIKDAEEGLLHLKRSRLVKQIDEIFPNQEPTSEAPEVAVDPPDDVEPEPLEPQEFSVGSKCRFRHKDGRWYNGCVIGLEGSSDARISFLTPTSENMSMCKFFLQQRCRFGSNCRLSHGIVIPILSLKQFTPTRWQQSLVGSSILAASGHHSGLWRRAELESWDDDLKVGQVVFQDDGSSARLPSDSLSISEYADESDEDGEGSSSDEGSDFSEDGDQEDESVHQGLGLLESKNLSGVQTETAIFAKWEHHTRGVASKMMAKMGYREGMGLGVSGQGMLDPIPVKVLPPKQSLDHAVAASEVNDSVGPGKKRSRGGKRKREKKFAEQARAAKAEEEERSVFSFINSQLVGQDVAEGSAVKSKKDSSGEANGHAKKEDRRSLLAYDDEVKELRSRVEKLEEMMKRNRKDKAFYEAASKKLKQTRKALADAEATHASATNAVARKEKEKKWLKF
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 18, OsC3H18.
Protein: AMPA_SOLUE
Sequence: MQITIERKPLGQIEADALIVPVFEGRRDARFGAEDLFASGEVAGKALEMTLLHHAPGVRATRVLLVGAGAAGKFDAAGMRRLSGAAVRFLKAKSVKKIALVLDSEFSGSNFASAAVEGALLGNFEPDRYKTGNEKKSLDTFIVAGDTPELESAVARGRILAEAQNFSRDLVNEPANLLTPLGMADAARKMAAEFGLECEVLDRDAMQKLGMGSLLGVAIGSAEPPVLIVLRYRPAKSEGAAHLGLVGKGVTFDTGGISIKPADGMEKMKYDMAGGAAMIGAMRAIAQLKPAIPVSAYIPAVENMPGSRAQRPGDIVTAMNGKTIEVINTDAEGRLILADALTYARRQGCTHLVDAATLTGAVVVALGHLNVGLFANDDAMRDRVLAAAKDEGERMWSLPLEDDYKEYLKSGFADIANVGGRWGGAITAAIFLKEFAEETPWVHLDIAGTAWLDENKPYLAKGPTGLPVRTLARLAMDWKA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_BACAA
Sequence: MFQKVEGIVIRTTDYGETNKIVTIFSRELGKVSAMARGAKKPKSRLASVSQLMTHGHFLIQMGSGLGTLQQGEIISTMKEIREDIFLTAYASFIVELTDKATEDKKHNPYLFEMLYQTLHYMCEGVDPEVLSLIYQTKMLPVLGMRPYFDTCAICHQETDFVAFSVREGGFLCSRHAEQDQYRIPVGEAVHKLLRLFYHFDLHRLGNVSVKDSTKKQMRLVLNTYYDEYCGIYLKSRRFLEQLDKFQI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RHO_SALTI
Sequence: MNLTELKNTPVSELITLGESMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNYDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMMKRS
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: LSRK_YERP3
Sequence: MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGLLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERLVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI214_LACSA
Sequence: MILKSFLLGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRAHIMEEGEEGTEKKVSATTGFITGQLIMFISIYYAPLHLALGRPHTITVLALPYLLFHFFCNTHKHFFDYGSTNRNSMRNLSIQCVFLNNLIFQLFNHFILPSSMLARLVNIFMFQCNNKIIFVTSSFVGWIIGHIILMKSIGLLVVWIRKNRSIRKYIRSNKSFVSELANSMSIAGILNILLFVTCVYYLGRMPLPIINKKLNNLEKMDQAKLKNNTPLSYIYKNQEDLYLEILGKKDKEKSFSLFEKPILTFFFDYNRWNRPLRYIRKINKNLSVRKETSQYFFYTCQSDGKKRISFTYPPSLSTFGEMIARRISLSTLEKLSADALYTEWLYTNKEKNNNLNNEFINRIEALETVFLSINILDTKTRLCNVETEKKKNCLVNKKNYLVKMDDPFLTGMYRGRINKLFSSSIINQISIENYEKTYELNKIHYNLLPYPNSREYEHKIDPNSPDYEQKIEKLEKIQAQIDLNNRFIFLWTTIIAKLKGQKNSSRINEIGKKPPRWSYKLINELHQNYKKRRKEQGIIQGLRHQLRTRKYKHIYFLNRSTRTLETLKQSNLNNSNMDKKFNNKDLGFISYLEEPDFRRSLIKGSMRAQRRKLVIWGPYQGNPHSPLFLEKKQDFPFPISDLIKLFLNIKDRLGKKSEFEILNKQSPPKRNNQEDVMEFWETIPHGHKTRGILLLAQSTFRKYIKLPLLIIAKNIVRILLRQSPEWDEDFQDWNREIYLKCSSNGLQFSKTKFPKNWLRGGFQIKILYPFHLKPWHRSKLRLYDSDRDLKQQEDFDSCFLTVLGMETEHPFGPPRKTPSFFEPIFKDIDYKVEIRKLNFRVRRIFKKIKKKEAKAFFFIKQKIKELLKGNKIPLFLPREIYESSETQTEKDSIISNQIIHESLSQIRSTGWTNYSQAEEEMKHRIDRRKTIRNEIEIMKKNKINNAESSQKILKILKIKNIELLVKFFIEKIYIEIFLCIINMRRIPLQLFIQSTKKIIDNDKYINNNETNQERINKTKQNKIDFILSMTIKRAFDNLRNSKRKSDIFFDLSYLSQKYVFFKLSQTQIINFNKLRSILQYNGPSFCLKTEIKDFFGRQGIFHSELRHNKLPNYGMNPWKNWLRGHYQYDLSQITSSRLIPQKWRNRINQCQTSQNKDLNKWYSSEKDQLLDSKKKQNSKVYLLPNKEDNLKKNYRYDLLSYKYIHSETKKNYYIYRSSLETNNNQENSTRNKEKFFSILKNIPSKNYLGKSDIIYMEKNKDRKFLYKINKNIKVEPNKDQIKDKNKDQKKDKIHNNGLFYLPIDSNLEINYKKVFFDWMGMNEKILILNCLISNPKVFFFPKFVRLYHKYKEKPWFIPSKLLLFNLNITSNFSENQNINGKQEEYFLKQEEYFLKQEEDFLKQEEDFLKQEEDFLKQEEDFLKQEEDFFKFRPSNSKQYFELNNQNNIEEYFLESTEKLKIFLKGDFPLQLRWAGRVNQLNQKIMNNIQIYGLLLSLINVRKITISYIQRKEMDLGIMSRNLNLTQLMKTGILILEPARLSLKNDGQFFMYQIISISLVHKSKYQSNQRYQKQENVAKNIDKKNSDLLVPEKILSSRRRRELRILISFNLNLKNNTGVDRNTLVYNENKIKKMESIFG
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: SART_STAAC
Sequence: MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
What is the function of this protein?
Transcriptional regulator acting as an intermediary between major regulators SarA and agr and virulence genes.  Represses alpha-hemolysin (hla) gene expression (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarT, Staphylococcal accessory regulator T.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI36_MOUSE
Sequence: MSESEEISEFGYIMELLAKGKVTIKNIEKELICPACKELFTHPLILPCQHSVCHKCVKELLLSLDDSFNDVASDSSNQSSPRLRLTSPSMDKIDKINRPGWKRNSLTPRPTTFPCPGCEHDVDLGERGVSGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIYHPWGTVKAQHEYVGPTTNFRPKVLMCPEHETERINMYCELCRRPVCHLCKLGGNHSNHRVTTMSSAYKTLKEKLSKDIDFLIGKESQVKSQISELNLLMKETECNGERAKEEALAHFEKLFEILEDRKSSVLKAIDASKKLRLDKFHTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQASFEDYVVNISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDKADSYVLEYRKINRDEEMISWNEIEVHGTSKVVSNLESNSPYAFRVRAYRGSICSPCSRELILHTPPAPVFSFLFDEKCGYNTEHLLLNLKRDRVESRAGFNVLLAAERIQVGHYTSLDYIIGDVGVTKGKHFWACRVEPYSYLVKVGVASSDKLQEWLRSPRDAASPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMKKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVSFYDMDHMKCLYERQVDCSHTMYPAFALMGSGGIQLEEAITAKYLEYEEDV
What is the function of this protein?
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:19232519).  Involved in chromosome segregation and cell cycle regulation (PubMed:19232519).  May play a role in the acrosome reaction and fertilization (PubMed:12917430).
What are the official names of this protein?
E3 ubiquitin-protein ligase Trim36, Acrosome RBCC protein, Haprin, RING-type E3 ubiquitin transferase TRIM36, Tripartite motif-containing protein 36.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton. Note=Found in the acrosomal region of elongated spermatids and mature sperm (PubMed:12917430). Colocalizes with alpha-tubulin (PubMed:19232519).
Protein: METK_ECO24
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PSYA2
Sequence: MAGEQTTTEYISHHLTNWTYGYLPGEGWKVAYTAEEASAMGFKAIHLDSMLWSIGLGIVFCAIFWMVARKVTSGVPGKLQAAVEMIIEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMNLMDLLPVDFVPGLAGQIGAMMGHDPHHVFFKIVPTTDPNITLGMSFSVFILILFYSIKEKGLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFILIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL8_ENTH1
Sequence: MGRRTLSQRKGRGSIFKSRSHHKLGVAQHRAIDFFERHSTVRGLVKSIEHDPGRGAPLARVVFRNPRQYGLDKELFICAEGLYSGQYIYCGSKASLHIGNVLPIGQCPEGTVVCNVESKPGDRGIIARASGNYATVISHNADNETTRIRLPSGAKKTLKSNCRAMVGIIAGGGRTEKPILKAGVAYRMYKAKRTTWPRVRGVAMNPVDHPHGGGNHQHVGHPTTLKRSSPPGQKAGKVAARRTGLIRGGNKEGAADN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L8, 60S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS8_BURPS
Sequence: MSMSDPIADMLTRIRNAQMVEKVSVSMPSSKVKVAIAQVLKDEGYIDDFAVKADGAKAELNIALKYYAGRPVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIVSTPKGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TRPD_METCA
Sequence: MEIPEVLETLLAGKDLSPSAMRETMRKIMSGGATPAQIGAFLIALRCKGETVEEVAAAAQVLREMATKVPVSAPHLLDTCGTGGDASKTFNISTTAAFVVAAAGGRVAKHGSRSVSGRSGSADVLEAAGINIELTPDQVKTCIETLGVGFLFAQRHHGAMKYAIGPRRELGVRTLFNLLGPLTNPAGAPNQLVGVYTDPWVEGLARVLQQLGSSHVLVVHAEDGLDEISIAAPTHVAELKNGLITNYYVRPEQFGFRRAALSELAIDTVAASLKMMRGVLDNVPGPARDIVALNAGAAIYAADLTDSLEAGIRRAEAVIADGSARAKLEALAALSRQFAAS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: Y4214_BACAC
Sequence: MEYQYPLDYDWSNEEMVTMVKFYEAIEKAYEKGIIREELMGLYRRFKEIVPSKAEEKKIDKEFQEVSGYSIYRAIQRAKEIEEQKLVKM
What are the official names of this protein?
UPF0223 protein BAMEG_4214.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RNH2_SHEB8
Sequence: MATFKSLSEADLLAFSTGLIAGVDEVGRGPLVGDVVTAAVILDPSKPISGLNDSKKLSEKRREALFDEICDKALCYQVGRASPAEIDELNILHATMLAMQRAVAGLNIAPELVLVDGNRSPIFVAHNGAELTSHSIIKGDGLIASISAASIIAKVTRDREMDVLDAAYPQYGFAKHKGYPTKAHFEAIAEHGVFDQYRKSFKPVKALLGL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX1_HYLLA
Sequence: MCAARLAAAAAQSVYAFSARPLTGGEPVSLGSLRGKILLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
What is the function of this protein?
Protects the hemoglobin in erythrocytes from oxidative breakdown.  In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
What are the official names of this protein?
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEDD8_DICDI
Sequence: MLIKVKTLTGKEIEIDIDPTDKIQRIKERVEEKEGIPPSQQRLIFGGKQMGDDKPASEYSIEGGSVLHLVLALRGGL
What is the function of this protein?
Ubiquitin-like protein which plays an important role in cell cycle control.  Attachment of nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).
What are the official names of this protein?
NEDD8, Neddylin, Ubiquitin-like protein NEDD8.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus.