PharMolix/UniProtQA huggingface dataset:
Protein: RL30_AERHH
Sequence: MANTVKVTQTRSSIGRLPKHKATLRGLGLRRIGHTVELEDTPCVRGMINQVYYMVKVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TASY_TAXBA
Sequence: MAQLSFNAALKMNALGNKAIHDPTNCRAKSERQMMWVCSRSGRTRVKMSRGSGGPGPVVMMSSSTGTSKVVSETSSTIVDDIPRLSANYHGDLWHHNVIQTLETPFRESSTYQERADELVVKIKDMFNALGDGDISPSAYDTAWVARVATVSSDGSEKPRFPQALNWVLNNQLQDGSWGIESHFSLCDRLLNTVNSVIALSVWKTGHSQVEQGAEFIAENLRLLNEEDELSPDFEIIFPALLQKAKALGINLPYDLPFIKSLSTTREARLTDVSAAADNIPANMLNALEGLEEVIDWNKIMRFQSKDGSFLSSPASTACVLMNTGDEKCFTLLNNLLDKFGGCVPCMYSIDLLERLSLVDNIEHLGIGRHFKQEIKVALDYVYRHWSERGIGWGRDSLVPDLNTTALGLRTLRTHGYDVSSDVLNNFKDENGRFFSSAGQTHVELRSVVNLFRASDLAFPDEGAMDDARKFAEPYLRDALATKISTNTKLYKEIEYVVEYPWHMSIPRLEARSYIDSYDDDYVWQRKTLYRMPSLSNSKCLELAKLDFNIVQSLHQEELKLLTRWWKESGMADINFTRHRVAEVYFSSATFEPEYSATRIAFTKIGCLQVLFDDMADIFATLDELKSFTEGVKRWDTSLLHEIPECMQTCFKVWFKLMEEVNNDVVKVQGRDMLAHIRKPWELYFNCYVQEREWLEAGYIPTFEEYLKTYAISVGLGPCTLQPILLMGELVKDDVVEKVHYPSNMFELVSLSWRLTNDTKTYQAEKARGQQASGIACYMKDNPGATEEDAIKHICRVVDRALKEASFEYFKPSNDIPMGCKSFIFNLRLCVQIFYKFIDGYGIANEEIKDYIRKVYIDPIQV
What is the function of this protein?
Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton.
What are the official names of this protein?
Taxadiene synthase, Taxa-4(5),11(12)-diene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RSGA_HAEDU
Sequence: MSKHRLTQNQQRRINANHHKKITRSKFEWQDDMLGEIQAGTIVTRHAKHADVEAENGEIIRCNLRRTLKNVVVGDHVSWRKGSQQLQGISGVIEAVYPRHNELSRPDYYDGIKVMASNIDQIIIISAVMPVLSLNIIDRYLVICENAGIPALIVLNKIDLLSEQERQHVQQQLAIYENIGYQTLCLSANTGENMDKLDRYLANGTSIFVGQSGVGKSSLINQLLPEVHAITGAISDISGLGQHTTTASRLYHLPQGGNLIDSPGIREFGLWHLTPEQITLGYCEFQTILGNCKFRDCKHNTDPGCAIKHAVEKGLINPIRFENYHRLIESRDETKSQRHFRT
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_SACD2
Sequence: MYEIQSFHAGLYDSKNAPVLTGIMRGIEREGLRIDRDGKLAQTPHPVALGSALTHPQITTDFSEALLEFITPPTHRVEDLFKQLYDIQGYTLSKLDDELIWSSSMPCVLNDDATIPVAQYGSSNNGTMKTVYRVGLGHRYGRAMQTVAGLHYNFSLPDAFWSFLHREEYSLLDLQDFKDQKYFALIRNFRRYYWLLVYLFGASPALCGSFIKGREHNLQPLIDERTLHLPYATSLRMGDLGYQSSAQESLYVCYNDKQSYITTLCAAITTPIDEYKAIGLQDEKGEFKQLNTSLLQIENEFYSSIRPKRTAKHGETALSALRNRGVEYIEVRCLDIDPFDPLGVNKPQVRFLDTFLLYCALQDSPDTSPEESANILRNQKTVVTEGRSPKALIESFTKGKIPLKQAGEALIKAMRPVAELLDIAHETEEHTQSLETQLAAILNPELTPSARIISHLSAKKLPYAHYALAQSRHHHETLLAKKPSNNTMQQFEKMAAESLDKQTRLEQKNSGNFSEFLQEYYKQYQMCCDK
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: A29AB_DROME
Sequence: MYASNLLYLLALWNLWDLSGGQQDIPNGKATLPSPQTPQNTIDQIGINQNYWFTYNALKQNETLAIIDTMEMRIASSLLEFKAQMEIQLQPLKIIMRHHASNIKASNNIKMRRFEKVGSRHFHIEKNLMQTWFEAYVTCRKMNGHLANIQDEMELDGILALAPNNSYWIDISKLVENGGTFVSTLTGREPFFVKWKSNQDTKKKNQCVYIYAKEMSYDECFEKKSFVCQADQWA
What is the function of this protein?
Responsible for physiological and behavioral changes in mated female flies.
What are the official names of this protein?
Accessory gland protein Acp29AB.
What are the subcellular locations of this protein?
Secreted.
Protein: HNRPF_HUMAN
Sequence: MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD
What is the function of this protein?
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Plays a role in the regulation of alternative splicing events.  Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein F, hnRNP F, Nucleolin-like protein mcs94-1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RSMH_BORHD
Sequence: MGNIFHTPVLLDEIINLLEIVYVNDGFIFVDCTLGEGGHSSAVLRKYQNISVIGIERDDIILNRAKEFLVEFKGKVSYFNAWFDDFFSEYSLSSKANFILADLGISMFHYKMSGRGFSFFEDERLDMRLNPGAGGLSAYDIVNTFDKVRLENLIYEFGGEHYSKRIVSSILEYRKIKKIKTSRELQGIISKAYPRIKLKINPATKTFQALRIYVNDELFRLKRSLPLWVGSLSRNGILAIITFHSLEDKIVKEFFKGLSKEQYCILTKKPIIASFEEKRCNNASRSAKLRAIRKLYE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_BACLD
Sequence: MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEHTYETLKQHSFSYTFKTGIGEEALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIALANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQGENPKHIKRLIVTASGGSFRDRTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHKESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQADFERFRCLQFAYESGKIGGTMPTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIAKPSLQEIREVDKDARKFVQTLLT
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: QCR10_MOUSE
Sequence: MLSRFLGPRYRELARNWIPTAGMWGTVGAVGLVWATDWRLILDWVPYINGKFKKDD
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  QCR10 has a role in CIII assembly and RIP1 stability.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 10, Complex III subunit 10, Complex III subunit XI, Ubiquinol-cytochrome c reductase complex 6.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR11/QCR10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RPO3_SACSH
Sequence: MSINLLHKDDKRIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRLALIPFTSEEALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKMLYSKDIKSEDPSIVPISGDIPIVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYPKVEILGNCEKGATVCPEGVFELKDGKLSVKNELACTLCEECLRYCNGLIRISSVEDKYILELESVGSLKPERILLEAGKSIIRKIEELEKKLVEVIK
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAQ_XENLA
Sequence: MTLESIMACCLSEEAEEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFSAMQAMIRAMETLKIPYKYEHNKGHALLVREVDVEKVASFENPYVDAIKYLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRIATHGYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Golgi apparatus. Nucleus. Nucleus membrane.
Protein: CASA2_BOVIN
Sequence: MKFFIFTCLLAVALAKNTMEHVSSSEESIISQETYKQEKNMAINPSKENLCSTFCKEVVRNANEEEYSIGSSSEESAEVATEEVKITVDDKHYQKALNEINQFYQKFPQYLQYLYQGPIVLNPWDQVKRNAVPITPTLNREQLSTSEENSKKTVDMESTEVFTKKTKLTEEEKNRLNFLKKISQRYQKFALPQYLKTVYQHQKAMKPWIQPKTKVIPYVRYL
What is the function of this protein?
Casocidin-I inhibits the growth of E. coli and S. carnosus.
What are the official names of this protein?
Alpha-S2-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: POC1_YEAST
Sequence: MLFKQWNDLPEPKHLLDLPEISKNLQSLEVCPVPKVEFPQDLDVPQYSTAVITTKIMNPLFPKNLLQLTSIGEIKTTLTVKSPSLPQSSGKHSWNYDENFPNEVDPDQKNDTADETVYGFSFPIYSFGKTLLFSMEENFISISPIFGNMISRSIISQLAQFSPDIIVIGTSDKIASMKVMTENECTLQPPEFITGFIGSVLTQLIVGPSKGLKFKCLVAPSEGPNGFEKLSLSDMGSLVDLCGQWLGFEPSRYSEECYRLWRCDSAAIGAQSGLYI
What is the function of this protein?
Involved in 20S proteasome assembly.
What are the official names of this protein?
Proteasome chaperone 1, Proteasome biogenesis-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the PSMG1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHP_XYLFA
Sequence: MLEHELIVTNKLGLHARATAKLVQTMSKFQSNTTLSTKGREVNAKSIMGVMLLAASQGTVIRVRIDGEDEHTAMQALSELFENRFNEDT
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I.  Phospho-HPr then transfers it to the PTS EIIA domain.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SINMW
Sequence: MALKIRLARGGSKKRPYYQIVVADARSPRDGRFLEKLGSWNPMLAKDDEKRIELNAERVQHWIDQGAQPTDRVLRFLDQAGLAKRPARSNPVKALPGKKAQERAAEAKQKAEEAAAAASEAAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GATC_SULNB
Sequence: MQIDNTVLEKLEKLSHLRIDDSKKEEVMGQLSEILGYIDNLNELNTDHLDAAFSTLKGGTPLREDIPRTENNIARDILSRAPESKDDFFIVPAIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MATP_ESCF3
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDLLLTLENEPVKVNDWIAKHMNPALVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAHRRGKTLSETIVQLIEDAEHKEKYANTMSSLKQDLQALLGKND
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_SALA4
Sequence: MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQLLGRYWLITNGHGRETEVQGEGVVGVQPRIAPGEEYQYTSGAVIETPLGTMQGHYEMIDENGDAFTIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: APT_ALKMQ
Sequence: MNLDSKIRVIEDFPKKGISFKDITTLLKDKEAFRSMVDQLSDQLIDLDIDIVVGPEARGFLVGAPVAYKIGAGFVPIRKPGKLPGETISYEYELEYGTDSLEIHTDAIQPGQRVAILDDLLATGGTVVATAKLIEELGGEVVSINFLIELGFLNGGEVLKGYSVKSLLKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_XANOP
Sequence: MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKSVFPISSYSGNAALEYVGYKLGQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPDEGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANANDEISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSTVGRMKFNRRVGRKDVLGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENEYVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLVNVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLKKGDSVTDAYLDGLKKSDWFQLRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMATGESVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQRVDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAIHMELEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PA_I18A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPNVVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFDDCKDVSDLKQYDSDEPELRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: DAPF_MYCA9
Sequence: MKFTKGHGTQNDFVVLPDVHIKRDLSVAAVQALCDRQRGLGADGVLRVTTVGAALEGGVLAEKPAGVSSEDWFMDYRNADGSIAEMCGNGVRVFAHYLRSVGLEHRDEFVVASLAGPRPVRINSWSQLTADVTVDMGPVKEFGAGEAIVGGRRFSGLAIDVGNPHLACVDAVLTTEQLRILDVGAPVTFDEQLFPDGVNVEVLTAPSAGPANTVHMRVHERGVGETRSCGTGTVAAAYAALRHIGQRTGEVVVNIPGGQVRVTVTGESSFLRGPSMLLADGEISDEWWGGIGACG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_YERPN
Sequence: MNPIVINRLQRKLGYTFQQQELLLQALTHRSASSKHNERLEFLGDSILSFVIANELYRRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIHTIERLILEWYHSRLEEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLNEPVIGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_VIBVY
Sequence: MESLTLQPIKKVNGEVNLPGSKSVSNRALLLAALAKGTTRLTNLLDSDDIRHMLNALTKLGVHYELSADKTVCVVEGLGRPFTATEAQELFLGNAGTAMRPLAAALCLGKGEFVLTGEPRMKERPIGHLVDALREAGAQIEYLENENYPPLKINATGLQAGTVNIDGSISSQFLTAFLMAAPLAQGEVKIHIVGELVSKPYIDITLHIMKQFGVDVVNNAYQEFIIPAGQSYVSPGQFLVEGDASSASYFLAAAAIKGGEIKVTGIGKNSIQGDIHFADALEKMGAEIEWGEDYVISRVGRLKGIDMDYNHIPDAAMTIATTALFAQGTTAIRNVYNWRVKETDRLSAMATELRKVGAEVEEGEDYLIVNPPQQLTHAAIDTYDDHRIAMCFSLVALSDTPVTINDPKCTSKTFPDYFDKLASLSELA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_CYAP4
Sequence: MTSPTVSTDRPVLRYEVLGSRRFSNYWWATVITIGGTGFFLAGLSSYLHVNLLPIGNPVELFFIPQGIAIGFYGVAALLLAIYLWATIGWNVGGGYNEFNKETGIVRIFRWGFPGKNRQVEISARIPDVQAVRIVIREGVNPKRTIYLRLKGRGDIPLTRVGQPIPLTDLENQAAEIASFLGVAIEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MPPD2_PONAB
Sequence: MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS
What is the function of this protein?
Displays low metallophosphoesterase activity (in vitro).  May play a role in the development of the nervous system.
What are the official names of this protein?
Metallophosphoesterase MPPED2, Metallophosphoesterase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the UPF0046 family.
Protein: AGLP_HALVD
Sequence: MTIVKKVARLRDWIALKTGAIRSPMIAEVSGYAARFTVQSVEEIWRIRDLRGEQDVIRLLLEEAEEDDVLWDVGSNIGTHACICSTKANVFAFEPNPDTFDRLTENSDRAPGTVIPLRYGLSSSSGDISFEPSPIAANGTHKVSTEGSMTIKTISGDELVESGEVPKPNVVKVDVEGHELEVLKGMTNALQSVNFVIVEIHAGVDPKDVTKLLSEAKLSTEITKLNRDEDFVIGRRQND
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  S-adenosyl-L-methionine-dependent methyltransferase that modifies the hexuronic acid found at position 4 of the pentasaccharide.
What are the official names of this protein?
Hexuronic acid methyltransferase AglP, Archaeal glycosylation protein P.
What is the protein family that this protein belongs to?
Belongs to the FkbM methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS27_MOUSE
Sequence: MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).  Required for proper rRNA processing and maturation of 18S rRNAs (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.