PharMolix/UniProtQA huggingface dataset:
Protein: GLYC_PIRVV
Sequence: MGQFITLMQSIPEALNMAFNVALVIVSLLCVTKGLINLWKCGIIQLLMFLALAGRSCDGEYKIDRRHVLSHVEFNLTRMFDNLPQSCSINNTHHYYKGPENTTWGVELTLTNTSVMNRSDENVTSIRSLGFGNITNCDKTGEAGHTLKWLLNELHFTVLHVTRHIGALCRTTAGAGLLIQYNLTTSDKGGEVGRHLIASLAQIIGDNKAAWVGKCYNNCTSSGKCSLTNCEGGTHYKFLVIQNTTWPNHCSYSPMSTVRMIIQKTAYSSVSRKLLGFFTWDISDSSGQHVPGGYCLEQWAIVWAGIKCFDNSVMAKCNKDHNEEFCDTMRLFDFNQNAIKTLQLNVENSLNLMKKSINGLISDSLVIRNSLKQLAKIPYCNYTKFWYVNDTITGKHSLPQCWLVSNGSYLNETHFKNEWLWESQKLYNDMLLKEYEERQGNTPLALADLCFWSLVFFTTTVFFQLIGIPTHRHLIGEGCPKPHRLTSNSLCSCGFYKIPKKPFRWVRKGK
What is the function of this protein?
Interacts with the host receptor.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: XYN3_HYPJQ
Sequence: MKANVILCLLAPLVAALPTETIHLDPELAALRANLTERTADLWDRQASQSIDQLIKRKGKLYFGTATDRGLLQREKNAAIIQADLGQVTPENSMKWQSLENNQGQLNWGDADYLVNFAQQNGKSIRGHTLIWHSQLPAWVNNINNADTLRQVIRTHVSTVVGRYKGKIRAWDVVNEIFNEDGTLRSSVFSRLLGEEFVSIAFRAARDADPSARLYINDYNLDRANYGKVNGLKTYVSKWISQGVPIDGIGSQSHLSGGGGSGTLGALQQLATVPVTELAITELDIQGAPTTDYTQVVQACLSVSKCVGITVWGISDKDSWRASTNPLLFDANFNPKPAYNSIVGILQ
What is the function of this protein?
Glycoside hydrolase involved in the hydrolysis of xylan, a major plant cell wall hemicellulose made up of 1,4-beta-linked D-xylopyranose residues.  Catalyzes the endohydrolysis of the main-chain 1,4-beta-glycosidic bonds connecting the xylose subunits yielding various xylooligosaccharides and xylose.  Produces xylobiose and xylotriose as the main degradation products.
What are the official names of this protein?
Endo-1,4-beta-xylanase 3, Xylanase 3, 1,4-beta-D-xylan xylanohydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH4_XANOM
Sequence: MSATLPDVAVTEAFTLSAPLRWVGMQDIAIPVHLDAASGSGLAARASVQVDLPRAELKGIHMSRLYRLLDLHLQRPLSPAMLPQLLQALIESHADCASRAARLTLSFALMLRMPALRSEGLSGWRAYPVRIAAQCRAGRTTIQLQVEVLYASTCPCSAALSRQLLSDAFVQQHAWCDALPLQDVAQWLQDHGSYATPHSQRSVAQVCVDLPADTQGFAIQELIGLCEQALATPVQAAVRRPDEQAFARLNGANLMYVEDAARRLRKQLAEHYATFHVAVRHLESLHAHDAVAETGSDDETFFPAAL
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: ARGB_SYNSC
Sequence: MAQSTQHNDDALRVSVLSEALPYIQSFAGRRIVIKYGGAAMAHAELRSAVFRDLALLACVGVRPVVVHGGGPEINQWLQRLEIPAEFRDGLRVTDADTMDVVEMVLVGRVNKQIVNGLNQLGTRAVGLSGSDGSLVEARPWGNGSHGLVGDVARVNPDVLEPLLEKGYVPVISSVAATPDDGRAHNINADTVAGELAAALEAEKLILLTDTPGILEDRDDPDSLIRKLRLSEARQLIEDGVVAGGMTPKTECCIRALAQGVSAAHIIDGRVPHALLLEVFTDAGIGTMVVGRS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB5_MYCTU
Sequence: MSEVASRELRNDTAGVLRRVRAGEDVTITVSGRPVAVLTPVRPRRRRWLSKTEFLSRLRGAQADPGLRNDLAVLAGDTTEDLGPIR
What is the function of this protein?
Probable antitoxin component of a type II toxin-antitoxin (TA) system.  The cognate toxin is VapC5.
What are the official names of this protein?
Putative antitoxin VapB5.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: KHK_HUMAN
Sequence: MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
What is the function of this protein?
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
What are the official names of this protein?
Ketohexokinase, Hepatic fructokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: UF06_MOUSE
Sequence: HSEPGGAY
What are the official names of this protein?
Unknown protein from 2D-PAGE of fibroblasts, P50.
Protein: APOA1_ORYAF
Sequence: METKAVVLTLAVLFLTGSQARHFWQQDEPQTSWSRVKDLVTVYLDALKDSSRDYVSQFEASALGKQLNLKILDNWDTLSSTFTKLQEQMRPIFQKLWEDLDKETSPLREVLNKDLEELKQKVQPYLDQFQKKWQEEVELFRQKMAPLGTELREGSRQKLQELQEKLGPLGEELRDSLRSHVDALRTQLAPYTEEMRQRLASRLEALKESNLAEYHTKASEHLSALRENAKPALEDFRQGLMPVLEGFQKSVLAALDEATKKLNSQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFJX_ECOLI
Sequence: MTTQTQYDLVPANGSEFELSVTQVPDEQHIRFWPQHFGTIPQWITLEPRIFAWMDRFCDEYCGGIWSFYTLSNGGAFMAPDADGDDKWHLLNGMNGNGAEMSAEAAGIAVCLIEYSHHACLTECDAMTEHYYRLRDYALQHPESSAIMRIID
What are the official names of this protein?
Uncharacterized protein YfjX.
What is the protein family that this protein belongs to?
Belongs to the antirestriction protein family.
Protein: ASPD_METAR
Sequence: MFRIGIVGAGAIGKEIARAIDNGTVPAKLEAIYDRDTAEATSFAASLKSKPRVLPLEELVEASNFVVEAAAQSAVREVAIAALSRSRSVMIMSVGALADKELLETIRTMAKEHCCSIYLPSGAIGGLDAVKAASICKIDSVTITTRKPRDGLRGAPFIVRNNIDVDSMDEPTEIFSGPAAVAIKEFPANVNVAASLSLVGIGFERTLVRVVVDPTIKRNIHEISVRGEFGELHTVVENVPARSNPKTSFLAALSAIATLRQVCEPLKIGT
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: RS13_HAMD5
Sequence: MARIAGINIPDKKHAVIALTSIYGIGRTTALDICAKTGVSAAVKISELSEKQIEELREQVAKYTVEGDLRREVTLNIKRLMDIGTYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL6_RUMCH
Sequence: MSRIGKLPITVPKGVTVKLEGDNLLTVKGTKGTLSKKFNKDMIIKVEADQIVVQRPSDLKIYKSLHGLTRTLINNMVEGVTNGFQKTLEINGVGYRAQKQGKKLVLTLGYSHPVEMEDPEGIATEVPAPNKIIVKGIDKQVVGEVAAKIREKRLPEPYKGKGIKYETEVIRRKEGKTGGKGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ATP6_ACISJ
Sequence: MAADAHAPTASEYIVHHLQHLQNIKQKSIIDFSVVNLDSVAVSVILGVLGLFVMWLAARTATSGVPSRFQAAVEMLVEMVDNQAKANIHNAQSRKFIAPLALTVFVWIFLMNAMDLLPVDLLPVLWQVATGDSHAYLRVVPTADLSTTLGLSSAVLILCFVYSIKIKGLGGWAHELVTAPFGTSKNPVFALILGVVNLLMQIIEYVAKTVSHGMRLFGNMYAGELVFMLIALMGGAAAMSLSGVLLPVGHIIAGSIWAIFHILIITLQAFIFMMLTLIYLGQAHEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLD2_CAEEL
Sequence: MVMAQQQKNAERNDEHTRRNRSPSVDSVSRVQQQSGGFAFYNQQSNHQYQQSHPRRTSFSRDGNTGYYNNHSGNKRQTYNNQRGGRSYNHRGNSNYQQNGEYSGNQGCVPKYHQRNQNYPQLQPKYSYFQPHQRPIFNSTQGYGTYSVRRSSPPSPSALSSSTANSTSNRAPTQPPILLRHAEPASDKNHQGSDHEQNHDPKIHLYRSAGTAPGGYTQCPSPYKQPPPQPPSTPSSSDKRIEQQQAEDWPTRFQHPPPQFRRGQDPMPASIELQHKTANQTMPVDIVQTNQQKTVSSYERAAQFRASASELPTDSVDAKHPCFANERMQSALIGISPQLKTQQQSPGIPIQNEAEASAVMKAMRSFQFHNWPQMSHGSYYPMPYHLENQMRPMKSGDQLPLNQQNHNLSGFPAFVGKSSLVGSSLNTRNSSEADPEEMPRIMEKLDDEVTGADHDKTIDENRRRIHKSQEPRIGTEEKALNELPRKANRRNSSCSSISSVSESSSPSALDESTLTKILPTDNFRGGRGFASPSPPTSLLSEPLSRMDVLSEKIWDYHNKVSQTDEMLQRKLHLRDMLYTAISPVFPLSGLYVVGSSLNGFGNNSSDMDLCLMITNKDLDQKNDAVVVLNLILSTLQYEKFVESQKLILAKVPILRINFAAPFDDITVDLNANNSVAIRNTHLLCYYSSYDWRVRPLVSVVKEWAKRKGINDANKSSFTSYSLVLMVIHFLQCGPTKVLPNLQQSYPNRFSNKVDVRTLNVTMALEEVADDIDQSLSEKTTLGELLIGFLDYYANEFNYDRDAISIRQGRRVERAALAVRPKIHSNSEGDKETPPPSSSASTSSIHNGGTPGIPMHHSISNPHFWRSQWRCVCIEEPFTNSNTAHSIYDEMVFEAIKKAFREAHGELQHNHDLDKLMECEPIKASTTNTGAAVFAATYEGERPLAQQPNTIACASLRVLNSIPVSSGPGHYHYQQQSNQNLSRPQRPGSNQGYQMNNNRGFNGNNQQQHQNRRSFNNQSSSNPGNGSTGPRSSRSNENVRDSSRQQNSQKGSSGVSVSKENVASTTGVPVDKKQQNSNRKDDGNRTKRSPMVQSPEPAKTKSEKTPMASSNVSQ
What is the function of this protein?
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail.  Acts as a regulator of mitosis/meiosis required for progression through meiotic prophase during oogenesis and spermatogenesis and for promotion of the entry into meiosis from the mitotic cell cycle.  May act by regulating and activating gld-1 mRNA activity in germline.
What are the official names of this protein?
Poly(A) RNA polymerase gld-2, Defective in germ line development protein 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRS3_HUMAN
Sequence: MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
What is the function of this protein?
Role in sperm cell division, maturation, or function.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Bombesin receptor subtype-3, BRS-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCP_MYCTO
Sequence: MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESIAAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGRVLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLMYGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSADIREPIPSRLQI
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM04_MOUSE
Sequence: MLRLFQAASRASLRLSGSRVIHSLAEGAERPAEISEPRDSAGLLDPVLRKCELRIPVHRRPVQAWVESLRGFEQERIGLAELHPDVFATAPRLDIVHQVAIWQRNFRRISYANTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDSLELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVVAATSGLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP
What are the official names of this protein?
39S ribosomal protein L4, mitochondrial, L4mt, MRP-L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECA_UREU1
Sequence: MKENDKLEKLDPIATLEAKFAKSTYFIADEIKNEKVSAISTGSIHIDQITGINGIPVGKITEIYGNESSGKTTIALQTIAECQKKGGTAVLLDLEGSFDLNYAKSLKVDLTKLIITQPQTGEQAFDMIETLIKTNSIDLIVVDSVAAMIPESEYQANMSEALMGAHARLMSKGLRKIQPLMNKSQTAIIFINQLREKINTFFGNPEMTTGGKALKFYASLRIETRKADLIKEGINKIGIKTKVTTVKNKLAPPLQTCFIDVFFGHGFDYDNEIIDFAIQYGILKKNGSWFYFDDNKIGQGREQLKNTLLKNNELFTQVSEKTLAFVNNEKINQ
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBBP7_DANRE
Sequence: MADKEVYDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTVQWLPDVNRPEGKDYVVHRLVLGTHTSDEQNHLVIASAQIPNDDAQFDASHYDSEKGAEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPTSDVLAFDYTKHPSKPDPSGDCSPDLRLRGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISGAPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPASELEGQAS
What is the function of this protein?
Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.
What are the official names of this protein?
Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, RBBP-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_ALKPO
Sequence: MSNQAVANRYAYALFQLAEEKSILSQVVQEMELVKEVVNTTPEFLQLLSHPKVTTEKKRAFIENSFKDSLSETSLHTLLLLVENKRIESLVDMIDSFKEMSYEAQDMAEAVVYSAKPLTSEEQAQIAVIFAKKVNKAKLLVTNVVNKDLLGGLKIRIGDRIYDGSVKSQLDRLERQLIAGTR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYP1_BACCR
Sequence: MKQSMVFSPTLREVPADAEIKSHQLLLRAGFMRQNASGIYSFLPFGLKVLHKVERIVREEMERAGAVELLMPAMQAAELWQESGRWYSYGSELMRMKDRNAREFALGATHEEVITDLVRDEVKSYKKLPLTLYQIQTKFRDEQRPRFGLLRGREFLMKDAYSFHATQESLDEVYDRLYKAYSNIFARCGLNFRAVIADSGAMGGKDTHEFMVLSDVGEDTIAYSDTSDYAANIEMAPVVATYTKSDEAEKALEKVATPDQKAIEEVSAFLNIEADKCIKSMVFKVDEKLVVVLVRGDHEVNDVKVKNVYGASVVELASHEEVKALLNWEVGSLGPINVTGDIEIIADHAVASIVNGCSGANEEGFHYVNVNPERDFKVSQYTDLRFIQEGDQSPDGNGTILFARGIEVGHVFKLGTRYSEAMNATFLDENGKTQPLIMGCYGIGVSRTVAAIAEQFNDENGLVWPKAVAPFHVHVIPVNMKSDAQREMGENIYNSLQEQGYEVLLDDRAERAGVKFADADLFGLPVRVTVGKKADEGIVEVKVRATGESEEVKVEELQTYIANILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase 1, Prolyl-tRNA synthetase 1, ProRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLR2_CAPHI
Sequence: MPRALWTAWVWAVIILSMEGASHQASSLSCDPTGVCDGHSRSLNSIPSGLTDGVKSLDLSNNEITYVSNRDLQRCVNLKTLRLGANEIHTVEEDSFFHLRNLEYLDLSYNRLSNLSSSWFRSLYALKFLNLLGNVYKTLGETSLFSHLPNLRTLKVGNSNSFTEIHEKDFTGLIFLEELEISAQNLQIYVPKSLKSIQNISHLILHLKQPVLLVDILVDIVSSLDCLELRDTNLHTFHFSEASISEMNTSVKKLIFRNVQFTDESFVEVVKLFNYVSGILEVEFDDCTHDGIGDFRALSLDRIRHLGNVETLTIRKLHIPQFFLFHDLSSIYPLTGKVKRVTIESSKVFLVPCLLSQHLKSLEYLDLSENLMSEETLKNSACKDAWPFLQTLVLRQNRLKSLEKTGELLLTLKNLNNLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTQCLPQTLEILDVSNNNLDSFSLILPQLKELYISRNKLKTLPDASFLPVLSVMRISGNIINTFSKEQLDSFPQLKALEAGGNNFICSCDFLSFTQGQQALARVLVDWPDGYRCDAPSHVRGQRVQDARLSLSECHRAAVVSAVCCALFLLLLLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPRRDLCYDAFVSYSEQDSYWVENLMVQELEHFNPPFKLCLHKRDFVPGKWIIDNIIDSIEKSRKTIFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKIMNTKTYLEWPTDETQQEAFWLNLRAAIRS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: BIP_SPIOL
Sequence: MAVAWKSRASSIAFGIVLLGSLFAFVSAKDEAPKLGTVIGIDLGTTYSCVGVYKDGKVEIIANDQGNRITPSWVAFTNDERLIGEAAKNQAAANPERTIFDVKRLIGRKFEDKEVQKDMKLVPYKIVNRDGKPYIQVKVQEGETKVFSPEEISAMILTKMKETAETFLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKRGGEKNILVFDLGGGTFDVSVLTIDNGVFEVLATNGDTHLGGEDFDQRLMEYFIKLIKKKHTKDISKDNRALGKLRRECERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLEKNQIDEIVLVGGSTRIPKVQQLLKEFFNGKEPSKGVNPDEAVAFGAAVQGSILSGEGGEETKEILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVTIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKEKIDARNSLETYIYNMKNQISDADKLADKLESDEKEKIEGAVKEALEWLDDNQSAEKEDYDEKLKEVEAVCNPIITAVYQRSGGPSGESGADSEDSEEGHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein, BiP, 78 kDa glucose-regulated protein homolog, GRP-78.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: YCF3_SOYBN
Sequence: MPRSRINENFIDKTFSIVANILLRIIPTTSGEKRAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEVAESWFNQAAEYWKQAIALTPGNYIEAQNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL28_PSEF5
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVESEKRFVRLRVSAKGMRIIDKRGIDVVLAEIRRDGGKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MRAY_BACC0
Sequence: MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGAIAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYIGVWM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPG_BARHE
Sequence: MNTVYSLSKPLERRQSVAVTVGDVLVGGRSPIVVQSMTNTDTADVDATVAQVAALWQAGSQLVRITVDRYEAAAAVPKIRERLERLGFVIPLVGDFHYIGHKLLSEHPACAEALAKYRINPGNVGFGAKKDRQFAEIIEIACRYRKPIRIGVNWGSLDHVLLTRLMDENAQQENPLSGGEIMREAVVQSALHSALWAEEMGLKRDQIILSAKVSDVQDLIAVYSTLAERCDYALHLGLTEAGMGTKGIVASSVALGILLQKGIGDTIRISLTPEPGGDRTREVKVAQELLQVMGFRQFFPVVTACPGCGRTTSTVFQQLAQKIETDLHKNMSVWREKYPGVESLKVAVMGCIVNGPGESKHADIGISLPGTGESPAAPVFIEGQKVKTLRGTHIAEEFELLLSDYIHTRFGQG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.