PharMolix/UniProtQA huggingface dataset:
Protein: ASC2_DIDFA
Sequence: MSAQKPITHFGLRDITRYTTTVDSNGNGVFSRADQGDFEATMGDGRVARFDLFQAGQVPLNINDGADIKWSGENQPGLHVPNGVAFRMMDFAPEGGSDWHRAALFAFVIIVEGELELSLDGGETKVLLPGDTTLVRGPSHKVRNPSTAKPCRTLWVLLDITPTHINGKLLKHEMGHHTGEYQEGSK
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the selective antifungal agent ascochitine, an o-quinone methide that plays a possible protective role against other microbial competitors in nature and is considered to be important for pathogenicity of legume-associated Didymella species (PubMed:31554725).  The pathway probably begins with the synthesis of a keto-aldehyde intermediate by the ascochitine non-reducing polyketide synthase pksAC from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (Probable).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (Probable).  The HR-PKS (orf7) probably makes a diketide starter unit which is passed to the non-reducing polyketide synthase pksAC for further extension, producing ascochital and ascochitine (Probable).  The aldehyde dehydrogenase (orf1), the 2-oxoglutarate-dependent dioxygenase (orf3) and the dehydrogenase (orf9) are probably involved in subsequent oxidations of methyl groups to the carboxylic acid of the heterocyclic ring (Probable).  The ascochitine gene cluster also includes a gene encoding a short peptide with a cupin domain (orf2) that is often found in secondary metabolite gene clusters and which function has still to be determined (Probable).
What are the official names of this protein?
Ascochitine biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the oryJ family.
Protein: NUOD_MYCTO
Sequence: MTAIADSAGGAGETVLVAGGQDWQQVVDAARSADPGERIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRYWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMMELNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAYIRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVGYLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDAYGRYMIRVKEMWESMKIVEQCLDKLRPGPTMISDRKLAWPADLQVGPDGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACKA_STAA3
Sequence: MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF157_RAT
Sequence: MAPKKKSNKGGKEIQSKKKIGGRKDTSGSKTPELAMVEELKEFYHKQIQDLEDRLARYQRKWDELAVQEKLFRQEFEQLANNKKEIVAFLKRTLNQRVDEITDLNDQLQSLQVAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIALGIKLSSLEEFRLQKEELTEKYMALEEQLRRQEGEYKDYVYNLEKKSVLDKDRLRKEIIQRVNLVATEFRKVATNQMWETTRRAILENNNVTLQLSKVSKQGVQLLQENEQLKGAQGKLCQQLELLENTQEIMAKKNIGNQKVILMLTEKCRQQRKGTEEAEQLRLQLFQLEQNIETLEKANQTLRSEKDQLDEQLKEQRAEANRLQEELTKEQKIRTNLKTVLTQATSLLRDILQMRPETEDGDFDVVFQLQRKELLQQLLVLLSSAVVSKPQQDMGSHQDKQPAGLSKDSRLIAQTSKQGAASLLQQLSTITTYQPGDLGLVPRRLQVHIPPKPQDLRPLSCVTRMGICKLQNTTEIYPSGALKRFKKFTLPRPFLHTGRPSRCRKPDVAPVPP
What is the function of this protein?
Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility.  May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure.
What are the official names of this protein?
Cilia- and flagella-associated protein 157.
What is the protein family that this protein belongs to?
Belongs to the CFAP157 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: RLMH_LACP7
Sequence: MKITVVCVGKIKEKYLTMAIEEYSKRLSRYCKLEIIELADEKTPDNASPAEELQIKKKEGERILKNIKDNAYVIALAIEGKMLSSEELADKMQLLGVNGESHLAFVIGGSLGLDSEVLDRADFKLSFSKMTFPHQVMRTILLEQVYRGFRIMSGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_ACAM1
Sequence: MYLQQLHLIQFRNYVAQQVEFSAPKTILVGPNAQGKSNLLEAVELLSTLKSHRVSRDRDLVKDGESLSQVTATLQRESGPLDLSLTLRANGRRTVSVNSETIRRQLDFLGHLNIVQFSSLDMDLVRGGPGERRNWLDAVLVQLEPVYAHLLQQYQQVLKQRNAYLKHHRADDAPQLDPQQLVLWNQQLAASGSRVIQRRQRMLMRLVPLAGHWHQTISGHQEQLEILYTPNVSYDPQFPEQLYPQFLSQLEEKSMLEQLQGLSLVGPHRDEVTLLINGTPARQYGSQGQQRTLVLALKLAELKLIEEVVGEAPLLLLDDVLAELDLNRQNQLLDAIQTRFQTLITTTHLGAFDAKWLDSAQILTVKAGQVQFST
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIF_AQUAE
Sequence: MDKLREYLNLLKERFNALTPVQKALAVGIPLLLLSLGAVALIYLSQENYTVLYTGLSPDDLNAVVTELDKEGVKYKISPDGRTIYVPENVARELRLKLAAKGVPRKGIVGYELFDKSGIVLSRFQQLVNFKRAIEGELAKTIMSLDCVEFARVHIVLPEKSLFIREEEEAKASVFLKLKPGCELTPEQVKAIRNLVSGSVENLKPSQVVVVDDKGRDLTAYLDEEFKTNASQLKVKREFEKSLERKLQKTLEEVFGYGKVKVNVSAELDFSSMKKREELYDPDLTAVVSEQKKKERTTSTRAQGIPGTQANIPPATGRQGGGELITERKESITNYEVSKREIYFEDKTIKVKRISVGLVIDKDVKVNTEELKNLIIASAGLDPKRGDQVSIVSVPFVKPTVVAEKPKVPTYVYVAVALVSLVILGLVAFGLVKLLRRRPPAPTPAPAVPGVPPTVEEVRKKTPYEELLEIAKQEPEKVAMVLKKWLKEG
What is the function of this protein?
The M ring may be actively involved in energy transduction.
What are the official names of this protein?
Flagellar M-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FliF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: ISPD_CLOK5
Sequence: MKSNYAVIVAAGKGKRMKMPINKQFICIQGKPILYYSISVFSKNPLVDKIVLVCAEDEIEYCKQEIVKKYNFDKVVKIVSGGKERQHSVFNALKVLENCSVVLIHDGARPFVTDRIIEDGIKYSNMYGACACGVVPKDTIKIKGKEGFSYKTLVRKELFIVQTPQCFDYNLIYDCHKKLANNKVQVTDDTTVAEYFGNMVYLYEGSYDNIKITTPEDLIIAENIFKTHKYI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: LFTR_PECCP
Sequence: MRLYQLSSQSLQFPDPNHALDDPNGLLAVGGDLSVARLKAAYRQGIFPWFSPGEPILWWSPNPRAVLFPDELHVSRSMKKFLKRHTFHATLNQAFDDVIHACAHEHHDGTWITSEIISAYRQLHLAGKAHSVEVWQDDKLVGGLYGVEQGRLFCGESMFSRTDNASKYALLAFQQHFIHHGGHLIDCQVLNAHTASLGVSEIPRDRFLQQLSQWQDLAVDDGCWLPQQLAEPTL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZSWM6_MOUSE
Sequence: MAERGQQPPPAKRLCCRPGGGGGGGGGGGGSSGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGSAGGPGDDSGGGGGRQHGRGAAAGGSSSSPAATSAAAAAVAAGTGTPSVGAASAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQPEPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPEQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKVFLSQGGYHGSGKQLNMLFAKVREMLKMRDSNGARMLTLITEQFMADPRLSLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPWEDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLYTNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQQKQLEMFRTQKKELPHKSITSITNLEGWVGHPLDPVGTLFSSLMEACHTDGDAFSGFSDCTDNMGQCKSLEYHHLPAHKFLEEGESYVTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPHDAELAYKIALRAMRLLVLESTAPTGDLSRPHHIASVVPNRYPRWFTLSHIESQQCELASTMLTAAKGDVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATEVGVYALDSIMQSWFTLFTPTEATSIVATTVMSNSTIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYTQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIYKGKKKLMMLVRERFG
What is the function of this protein?
involved in nervous system development, important for striatal morphology and motor regulation.
What are the official names of this protein?
Zinc finger SWIM domain-containing protein 6.
Protein: SODC_DROER
Sequence: MVVKAVCVINGDAKGTVFFEQESSETPVKVSGEVCGLAKCLHGFHVHEFGDNTNGCMSSGPHFNPHGKEHGAPVDENRHLGDLGNIEATGDCPTKVSITDSKITLFGADSIIGRTVVVHADADDLGKGGHELSKSTGNAGARIGCGVIGIAKV
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_PSESM
Sequence: MPDATLSNTSLGRLAWLWLTVLIVAVDQVSKYYFENALSLYQQIIVIPDYFSWTLAYNTGAAFSFLADGAGWQRWLFALIAVVVSAVLVVWLKRLGRDDTWLAIALALVLGGALGNLYDRVVLGHVIDFILVHWQNRWYFPAFNVADSAITVGAIMLALDMFKSKKTGETVND
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_RICAH
Sequence: MSILHATILTVFPEMFPGTLGDSLAGQALKKNIWSYDVINIRDFGLTKHKNVDDEAYGGGDGLIMRPDVLGNAIEHALSLNPNASIYYPSPRGRVFTQSFTKEMLKNKNLIFLCGRYEGIDERVIEEYNVEEISVGDYILSGGEIPTLAILDCLIRLLPGVLMNQNTLSSESFEEDGEFKGGLECSLYTRPKIWRGRAVPSVLLSGNHKLINEWKKEQSRMITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_RHIE6
Sequence: MTRPTSSAPSQRMLRVGEQVRAAITQVLQRGEVRDDIIEATVISISEVRMSPDLKIATAYVTPLGVSDHSIVIEALNRHAKFIRGRLGPQLRQMKYMPEVRFRDDTSFDNYKKIDELLRSPEVSRDLDGDNDDQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_TERTT
Sequence: MADLIALFVRSVFIENMALAFFLGMCTFLAVSKKVDAAIGLGVAVVVVQTVTVPVNNLLYTYFLADGALAWAGLPNVDLSFLGLITYIGVIAALVQIMEMFLDRYVPALYNALGVFLPLITVNCAIMGGSLFMVERDYNFAESVVFGTGSGFGWALAITALAGIREKMKYSDVPEGLQGLGITFIVVGLMSLGFMSFGGISL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2424_STAA3
Sequence: MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTLKLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNTRTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLKKEIENFKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSRSLEFTFVENKEENIYFTDSVQYTPSEDTRYESN
What are the official names of this protein?
Uncharacterized protein SAUSA300_2424.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YORN_TTV1K
Sequence: MKYIFISYTYYHSYSISIGIYALLCFTLFLLLPLIDTPRYPRTTYYQRNAATVAQLVCTLTFVCPLKLRVG
What are the official names of this protein?
Uncharacterized 8.3 kDa protein.
Protein: C71BY_ARATH
Sequence: MATIWFLPLLFLSCLLLAALRLKKRRQHQRKPPSPPGFPIIGNLHQLGELPHQSLWSLSKKYGPVMLLKFGSIPTVVVSSSETAKQALKIHDLNCCSRPSLAGPRALSYNYLDIVFSPFNDYWKELRRMCVQELFSPKQVHLIQPIREEEVKKLMNSFSESAAQKTPVNLSEKLASLTVGVICKAAFGVSFQGTVLNSDNFDKLIHDAFLFLGSFSASDYFPNVGWIIDWLTGLQGQRERSVRGLDAFYEQMFDLHKQGNKEGVEDFVDLLLKLEKEETVLGYGKLTRNHIKAVLMNVLLGGIGTSAITMTWAMTELMRNPRVMKKVQSEIRNQIGGKSMICLDDIDQLHYLKMVINETWRLHPPAPLLVPREVMSEFEINGYTIPAKTRLYVNVWGIGRDPDTWKDPEEFLPERFVNSNIDAKGQNFELLPFGSGRRMCPAMYMGTTMVEFGLANLLYHFDWKLPEGMVVEDIDMEESPGLNASKKNELVLVPRKYLNL
What are the official names of this protein?
Cytochrome P450 71B37.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACNA_COREF
Sequence: MTESKNSFNAKSTLQVGEKSYDYYALSAVPGMEKLPYSLKVLGENLLRTEDGANITEEHIEAIANWDASADPSIEIQFTPARVLMQDFTGVPCVVDLATMREAVKTLGGDPDKVNPLNPAEMVIDHSVIVEAFGRPDALEKNVEIEYERNEERYQFLRWGSEAFSNFRVVPPGTGIVHQVNIEYLARVVFDNDGLAYPDTCIGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPVGVTATDVVLTITEMLRDHGVVQKFVEFYGNGVKSVPLANRATIGNMSPEFGSTCAMFPIDEETIKYLRLTGRPEEQIALVEAYAKAQGMWLEQDAPEAEYSEYLELDLSTVVPSIAGPKRPQDRILLSEAKEQFREDLKAYTNDPVQVDQSIPAKRMANEGGFQPGSTSDLDNYNASWPGEGESAAANAEGRPSNPVTVVSPQGGEYTIDHGMVAIASITSCTNTSNPSVMIGAGLIARKAAEKGLKSKPWVKTICAPGSQVVDGYYQRADLWKDLEALGFYLSGFGCTTCIGNSGPLPEEISEAINEHDLAATAVLSGNRNFEGRISPDVKMNYLASPIMVIAYAIAGTMDFDFENEALGQDQDGNDVFLKDIWPSTEEIEETIQAAISRELYEADYADVFKGDKQWQELDIPSGKTFEWDENSTYIRKAPYFDGMTAEPQPVTDIENARVLAKLGDSVTTDHISPASSIKPGTPAAQYLDAHGVERQDYNSLGSRRGNHEVMMRGTFANIRLQNQLVDIAGGYTRDFTQEGGPQAFIYDACVNYKEAGIPLVVLAGKEYGTGSSRDWAAKGTNLLGVRAVITESFERIHRSNLIGMGVVPLQFPEGESHESLGLDGTETFDITGLTALNEGTTPKTVKVTATKENGEKVEFDAVVRIDTPGEADYFRHGGILQYVLRQMAAS
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: YOR1_COYMV
Sequence: MNVWLLKSHTPLGLLPYYSLLDPFCFMNQVDQVKQKLIDWLSSAKKLSEEVIVFTPEVKINLRDLAHNIHIIAHRVALGFKVIYLYLVDIIFPLLKNIQKSQKESSENLQSVLKIVKEQRRSLKQIEDQLSKVQSELAKLREDYLSRRPLSKQDVEELVVRISEQPKFIEKQTEALTEELKLKVEEVAKLIHSFKGMVLN
What are the official names of this protein?
Uncharacterized 23 kDa protein, ORF1.
Protein: RHAS_YERPB
Sequence: MTVLHSIDFFSSSSAPVAIEARAPQSAFPEHHHDFYEIVIVEEGAGVHVFNGNPYTLSRGCVCFVRDHDRHLFESTDDLFLTNVLFRAPDAFRFLSGVGHFLPRECDGVYPSHWRVNGQVLQQIKCLIACLEHAPKSDQVEDIALHESVFMQLLVKLWQGCQTQAGDDQEGRLYQLLDWLQNNYSEAVEWPELADRFALPLRTLHRQLKNKTGMTPQRYLTRLRLLQARHQLCYSDNSVTDIAYLCGFGDSNHFSTLFKREFSQSPRDLRSQL
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_LISIN
Sequence: MSDYQVLLYYKYTTIDDPETFAKEHLAACKEMELKGRILVATEGINGTVSGTVEATNKYMDYMANDARFADMVFKIDAADSHAFKKMHVRPRAEIVSLSLEEDVNPLEITGDYLEPAEFRDALLDEDTVILDARNDYEFDIGHFRGAVRPDIQNFRELPGWIEDNRDQLEDKKIVTYCTGGIRCEKFSGWLKTAGFEDVSQLHGGIATYGKNEETKGELWDGQMYVFDERIAVPINQVNPTIVGKDYFDGTPCERYINCANPYCNKQILASLENEKKYLRSCSHECRVHPANLYTKELSKEEFTERLQAIDETLPETVQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y1364_ACIAD
Sequence: MTALAEILGCYFPYLILKEGKTHWLWLPAIISLAVFVWLLTLHPAASGRIYAAYGGIYIFTALMWLRFIDQVTLTRWDIWGGTVVLLGAALIILQPQGLLK
What are the official names of this protein?
UPF0060 membrane protein ACIAD1364.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1119_HAEIN
Sequence: MAIQMTTKTTYQWPQSKDIYPYRPGRFDAPKHWRYNLRSFLNRGSIRRFEQFINQHPFLIDIFNTHLDYSYPVACRFLDKRFNASQRFHAVCENLLFLPEKLTALSTPLWEKPLSFGEVIPDFEMTLSMTTHQPMEGYWVLELWHKPRNELVYLLTFAKLGDALLIAVVQGPNFEGSKEMVKQLTKLCHGLRPAYLMVETMKSLTKILGYNKLLGIPQKYQNKSRFIQSKQYTVDYDAIFGESGGELKDYWELPLEMDRNLDDIPSKKRSMYRKRYAMLDDLAKVIEEKLGL
What are the official names of this protein?
Uncharacterized protein HI_1119.
Protein: ZYX_XENLA
Sequence: MDPAAPATRMTSSFTINISTPSFYNPPKKFAPVVPPKPKINPFKAPEEPQSLVPQENSAGPGLHQAFVGKVGEMPPGVDHDDFVLPPPPPSEESISPPSSSFPPPPPSFGDEGLGSPSGGSFPPPPPPEFSEPFPPPIEEFFPSPPPLEECVSDTQDLPVPVPPPPPPPLPSPPAAPPPKPSAPCEAPKPAPVFPKSSPPPAFPKPEPPSVAPKAASSIFIPKPSAPMAVAPKPLAPPPVAAKPSGPVSFAPPSPAPHTFSPDPSAPAHTFSPKTVTFSPKSAPHTFMPKPSAPVTYPQKTTEPPAEASQSSPKVTPAAKHEAPPPTVPSGGRAPGFSFAQQRERPRVLEKPRANLQGSEPEHEPTVEVQVERTRSLGPQTESGRSPGAQSTGGKDMKPLPEGLRSQKPMSDGIHRTGGQHSGHKVTGQQDQTLGSQGLNMKEVEELEMLTQQLMREMDKPPTAEAHSMELCGFCGRGLSRTETVVRAGEHLYHVACFTCSRCDQQLQGQQYYESAGKPLCDECYQDTLECCAVCDKKITERLLKAIGKSYHPSCFTCAVCKCSLQGEPFIVDDNKLPHCVNDYHRRYAPRCCVCGDPIAPEPGRDETVRVVALEKNFHMMCYKCEDCGCPLSIEADDAGCFPLDGHVLCKKCHTVRARAALG
What is the function of this protein?
Adhesion plaque protein.  May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).  Suppresses the transcription-repressing activity of hesx1/anf1.
What are the official names of this protein?
Zyxin.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Note=Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of hesx1.
Protein: PLSX_COXB1
Sequence: MLKTIALDAMGGDHGPKVIVPAALSILKKHPKVKLILVGKEDQLALLIPEKNRKSFGQRLEIIHASEEVGMDEPPSQALRTKKNSSMRVAINLVKEGQAHACVSAGNTGALMATARYVLKTLPGIDRPAIIAAFPTKNEREVRVLDLGANVDSTPENLYQFAVMGSILSSAAHNIRNPRIGLLNVGEEEIKGNELVKKANELFETRKTINYIGYVEGNTIFNNIADVVVCDGFVGNAVLKASEGVAQLIKQHAKEAFSEAWWTKLALLPAIPILKRLIRRVDPERYNGATFLGLNGIVVKSHGSANIKAFVCAVEEAIFQVDKNIPQLIKEEVAHILKEFENK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DXS_BACC2
Sequence: MDLTQIQNPSFLKDMSISELEGLSEDIRKFLIEELSQTGGHIAPNLGVVELTIALHKLFDSPQDKFLWDVGHQSYVHKILTGRAKEFGTLRQYQGLCGFPKRCESEHDVWETGHSSTSLSAAMGMALARDLKKTKEYVIPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNVLGRLRTAGKYHWVKDELEYILKKIPAVGGKVAATAEKIKDSLKYLLVSGVFFEELGFTYLGPVDGHDYEKLFETLQYAKKTKGPVLVHVITKKGKGYKPAESDVIGTWHGTGPYKIESGDFVKPKEVAPAWSAVVSETVLKLARADERIVAITPAMPVGSKLEKFQKEFPNRMIDVGIAEQHATTMAAGMATQGMKPFLAIYSTFLQRAYDQVVHDICRQNLNVFIGIDRSGLVGADGETHQGVFDISFLRHLPNMVLMMPKDENEGQHLVYTAMQYEDGPIALRYARGNGLGVHMDEELKAIPIGTWETLKEGTQAAILTFGTTIPMAMEAAERLEKAGVSVKVVNARFIKPMDEAYLHDLLGKNIPILTIEEACLIGGFGTGVVEFASENGYHSALVERMGIPDRFIEHGSVTKLLEEIGLTTDAVVDRIHTMIPSKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RFBB_VIBCH
Sequence: MKELTCFKAYDIRGQLGSELDNEIAYRIGRSYGQFLKSENDADKTVVVGGDVRLTSEALKQALANGLMDAGINVIDIGVTGTEEIYFATFYLGVDGGIEVTASHNPMDYNGMKLVREGSKPISGDTGLREIQALAEKNEFMDVEVKGNYKKVSLLPEYVDHLISYITPAKIKPMKLVINSGNGAAGHVIDELEKRFIELSIPLEIIKVHHEEDGNFPNGIPNPLLPECRADTANAVKEHKADMGIAFDGDFDRCFLFDENGDFIEGYYIVGLLAEAFLQKEQGAKIIHDPRLSWNTIDVVTKSGGVPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFGYCDSGMIPWLLITELLSLAPDISLSKLISAKRFLFPCSGEINFKVKQAKLIMEQVYLHYYENSIHFSAIDGISLEFEGWRFNLRDSNTEPLLRLNVESKQNIALMNDKVEELTKLIKKLDI
What is the function of this protein?
Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides.
What are the official names of this protein?
Phosphomannomutase, PMM.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cell membrane.