PharMolix/UniProtQA huggingface dataset:
Protein: SKFB_BACSU
Sequence: MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAFLLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSYLPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEAKLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQLRGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTLSVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAWYIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLPFQKEVKAGIQE
What is the function of this protein?
Catalyzes the formation of the thioether bond required for production of the sporulation killing factor (SKF) from SkfA (PubMed:12817086).  Forms the cysteine-methionine thioether bond found in SKF; the acceptor amino acid can be hydrophobic, aromatic or a small hydrophilic amino acid but not a larger hydrophilic amino acid, i. e.  Met=Ala, Phe, Leu, Tyr>Asn, Ser>>Gln, Glu, Lys (PubMed:23282011).  The relative position of Cys and Met in the substrate cannot be inverted, in vitro the thioether bond cannot be made in the absence of the SkfA propeptide, suggesting this is the first reaction in SKF maturation (PubMed:23282011).  In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA (PubMed:23282011).
What are the official names of this protein?
Sporulation killing factor maturation protein SkfB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_RUEST
Sequence: MAKNKFHDGPGPSQRQLRVGEVIRRTLSEVLARGDIHDPELNRLSITVGEVRTSPDLKIATAYVLPLGGKGQEDVLQLLARNKSELRRAIGKKTGLKFTPDLRFQIDETFDRMDDTRRLFNQDAVRRDLED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANR22_MOUSE
Sequence: MGILYSEPICQAAYQNDLGQVWRWAKESNHYVDVQDSFNGDTPLICACRRGHLRIVSFLLRRNADVNLKNLKERTCLHYAVKKRFTFFDYLLIILLMPVLLIGYFLMVSKTKQNETLVRMLLNAGVEVNATDCDGYTALHYACQMKNQTLIPLLLEAHADPMIKNKHGESSLDIAQRLKFSQIALMLKRAS
What are the official names of this protein?
Ankyrin repeat domain-containing protein 22.
Protein: US24_HCMVM
Sequence: MMDPAAGSGPDGAAVVPPELPALPVAAEDPMALYRQVLRDFKELFFCLEPMEITRYVHRNEGRCLSLGPPKGWHVMLRTEDGIITAAKQAASKLICCREPLTPLGYAVILLPEPRRDHHDGMVATPYVVFMGRFSRVYAYDTREKYMVLVSHNLDELARYGVSRSEIAYRDVIHTTLRRMTVPVPRRYPKGARTMHVLFLNDTTPEGSYATAERILGCDVKLHTPGYGTVIMRLMKTVQQLHRIWPFCALTEVESRRWWWAVRANLATPWYVLGVTGRPRPGRSFVAEVLVLLDWFGAVYAIQMDDPNHYVRRVANTITEFFRMGLLKMVFRHRRFERERQRQTRMEHRHLCPHHHERAVDHKRDILFNEDAALPDERRERERRILQQQYDWLCLTERFDPHEGAWERLDPNTLVLHRYDTNSQSYVLDPDIVGVEAAEREAAGHQDDTGPRLHCLVTTRSSTREGAERVITALVHQSRLVTYSDPFPLKSLTGVREYIQI
What are the official names of this protein?
Tegument protein US24.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: HEMA_I63A4
Sequence: MKTTTILILLTHWVHSQNPIGGKNTATLCLGHHAVANGTLVKTITDDQIEVTNATELVQSTSTGKICNNPYRVLDGRNCTLIDAMLGDPHCDVFQYGNWDLFIERSSAFSNCYPYDIPDYASLRSLVASSGTLEFMAEGFTWTGVTQNGRSSACRRGSADSFFSRLNWLTKSGNSYPTLNVTMPNNDNFDKLYIWGIHHPSTNNEQTKLYVQASGRVTVSTKRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDVLMINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCVSECITPNGSIPNNKPFQNVNKVTYGKCPKYVKQSTLKLATGMRNVPERQIRGIFGAIAGFIENGWEGMIDGWYGFRYQNSEGTGQAGDLKSTQAAIDQINGKLNRVIGKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDAEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIRGVELKSGYKDWILWISFAISCFLICVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: TRPR_HAEI8
Sequence: MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQREIQQNLNTSAATITRGSNMIKTMDPDFMQWMKQHLDLIEKN
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_MARN8
Sequence: MTTLFISDLHLEESRPDITGAFLTFLRDKALGVERLYILGDFFEAWIGDDERTPLQEQVAAALREVRDTGTDIYLMHGNRDFLIGEDFCARAGAILLDDPTVVDLYGTPALLMHGDSLCTADVEYQKFRANMRNPQTVKMLLSRPLKDRQLMARQLREISMAKNQGKAETIMDVTPEEVVKELEAHNVQLMIHGHTHRPAIHELEANGRPARRIVLGDWDENVWWLEASKNQPVALRHQPLADF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS8_PROM0
Sequence: MSNHDPISDMLTRIRNASQKKHTTTSIPSSKMSLSIAKVLQKEGFISDINEEGEGYKSQIILGLKYSGKNKFPTIRSMQRVSKPGLRIYKNTRALPKVLGGLGVAIISTSKGVMSDRDARKQGIGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: INO80_GIBZE
Sequence: MDQNGYNSSALQRPPRRGDEGCEEDRDSRPHHHHRHHHHHHHHRRDGDLPAGAVAGEAATASSNAGGANAHQHSTFSLRSPKPEYRPPPFSSPNGHNHSHHNTSTSSANHSLQSPPRPALPNPYMSSSTGAPGGPVAPALPPPVGINSSSSPGSSAAGLHQRHHQPGAPAHQHRAAPPPVSPLHPPVAYYPPGTNTDIYIPPPEPKPASRGFYDPTTDTTKERRISDAATPGASWHNANANAPPAGTPKTRDPYSYSQTADQHTPSYYNGGSYTSPRGPSYNRPRSPLSHSHQNPPAGSLSPPGQQPLLASPSVRHGTTANMNPTTNGASAIPPFKSDLAAPSPPKPAPSSTTSRANPMSFDSILSSSEPAPKPKEPSPIIAREPEIKEEREPRRDRESKRDSREPKQTKRSLEPELDHDTEVEKDVETEPEPLPSREKEKEPAPKKRGARKSTKGRASDIRDAATPKNGRRLSVKKESPTPRLPAKRQANGQPKPKTWSAEMEKKIQNAESDIENRAANLDADEFDEQQYKERAQKRRRVMSELDVEYGLSRRDALANTISKKLVLHAELGKRRYDDVFYDEALHEVREQEVYAEKERKKDMQRKRRREKSMAVTMEQKEAALARAEAAEDETERQKHLRDAERASKKAQQTKLILQKGIKGPARNLEINLEGGTMSSFQASDVESGEAGTPSGKRKGKGRSGPRLKKSKEQKQAEKDSAEAAQAALDAGEELPTKEENRVRIKIKKTKKDVAVDSEKDKDEAEKTEEEVVEKKTKKSKDKDKEKVDDIPDNEKRFMSKGYNQIYDQIWRDMARKDVNKTFKLAVDSYATKASNLKKTAILASKEAKRWQLRTNKGTKDLQARAKRVMRDMMGFWKRNEREERDLRKAAEKQEIENARKEEADREAARQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDNPEIAKDAHQTDQKMLDIDEPTGPVIGKVTNFENLDFEEGSDEALRAAAMANAQNAIAEAQKKARDFNNQGLDMDDEGEMNFQNPTGLGDVEIEQPKLINAQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEKHDIWGPFLVVAPASTLHNWQQEIAKFVPEFKILPYWGGASDRKVLRKFWDRKHTTYRKDAPFHVCVTSYQLVVSDVAYFQKMRWQYMILDEAQAIKSSQSSRWKALLNFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIELDIFCDLTYRQRAYYSNLRNQINIMDLVEKATMGDDQDSGTLMNLVMQFRKVCNHPDLFERAEVNSPFACAYFAETASFVREGNDVAVGYSSRNLIEYELPRLVWRDGGRVHKAGPDSQVAGWKNRTLNHLMNIWSPDNIRDSSDGSKAFSWLRFADTSPNEAYQATHQSLIARAAKELQKRDRLGYMNVAYSDTEDANFTPAHALFQIRPRQNRKPLADITNEGILSRLMNVAQGDYDESGLGRLEPAGRPRASAPPIQVSCRSWASEFERSEVLFNAPIRKILYGPTVFEEKALVEKKLPMELWPTRQMLPKPDHEKKGFTNISIPSMQRFVTDSGKLAKLDDLLFKLKSEGHRVLLYFQMTRMIDMMEEYLTYRNYKYCRLDGSTKLEDRRDTVHDFQTRPEIFIFLLSTRAGGLGINLTTADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLITRGTIEERIRKRAMQKEEVQRVVIQGGGASVDFSGRRAPENRNRDIAMWLADDEQAEMIERREKELLESGELEKQQKKKGGKRRKAENSASLDEMYHEGEGNFDDGSKGVSGTATPATAATPADSDSKGKKGRKGTKRAKTAKQRLAIADGMME
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSB4_ENCCU
Sequence: MDSSIGIKGRNFAIVAADTKISSSILVVKENHEKFQVIKDRIVMAMTGNQGDAFRTMLYVSESALYEEIQNGIELSPSVLAHMIQNKVHESLRRRQLDISSIVAGRGPEKYDLWSVDKYGAISSVPFCASGYAAYFVYGILDREYSEDITIDAALSIMQKCVNLLKERLMINLEGFMVKIVTDDGILTRTLVPEIKG
What is the function of this protein?
Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit beta type-4, 26S proteasome beta-type subunit PRE1, Multicatalytic endopeptidase complex subunit PRE1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DIR10_ARATH
Sequence: MAGQKILSLLVIALVVTFAAAARLLDEENAFSATTTTLGSGSGSTGIGFGAGTGSSGSGSTGFGFGAGSGSSGSGSTGSGLGAGTGSIPSSGSGPGLLPTASSVPGSLAGGGSGSLPTTGSATGAGAGTGSALGGGPGAGSALGGGAGAGPALGGGAGAGPALGGGAGAGSALGGGGAGAGPALGGGGAGAGPALGGGVAGSGSALGGGASAGPDNTLVFFMHDILGGSNPTARAVTGVVANPALSGQLPFAKPNGANLPVSNGVPSNNNNNGIVNNNNVPFLVGLGGTTANILQNNNNGNNILNGFPVASGGQLPSGSALQMLMFGTMTVIDDELTEGHELGSGLLGKAQGYYVASAIDGTSQTMAFTAMFESGGYEDSISFFGVLRTAVSESHIGVMGGTGKYVNARGFAILKTFTGSSGTQQNQPHQFTDGLETVVECTVYLSY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism (By similarity).  Regulates suberin accumulation in roots.
What are the official names of this protein?
Dirigent protein 10, AtDIR10, Protein ENHANCED SUBERIN 1.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: SYS_SOLM1
Sequence: MLDLKFLRQNPEAVAAGLARRRFPFDLDAFLALEERRRACITAAEQKKSQRNAASAEVAKAKRAGGDASAALAGLGALSDEIKALDEDAKAIDAEVAALLLGVPNLPHATTPDGASEADNPEVRRWGQPREFTEFAPREHQDVGAALGLDAERAVKLSGARFAVLRGALARLERALAAFMLDLHTGSHGYVEVVTPYIVTDECLVGTGQLPKFAEDLFKLEGRAAYLIPTAEVPVTNLHRGEVLPESALPLGYTCHTQCFRSEAGSYGKDTKGLIRLHQFGKVELVRFVHPDTSYDELEKLTNQAEAVLQALELPYRVVALCAGDIGFSSAKTYDLEVWLPAQGKYREISSCSNFEDFQARRADIRFKPDGGKKTAYVHTLNGSGLAVGRTMAAILENGVQADGSVVLPRALVPYMGGLEVLEPEGKRA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_ECO55
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPOC2_SPIOL
Sequence: MEVLMAERANLVFHNKAIDGTAMKRLISRLIDHFGMAYTSHILDQLKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAVEKLRQSIEIWYSTSEYLRQEMNPNFRMTDPYNPVHIMSFSGARGNVSQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRRDCGTIRGISVSPQNSTMPERILIQTLIGRVLADDIYMGSRCIATRNQDIGVGLVNRFITLRTQLISIRTPFTCRSASWICRLCYGRSPTHGGLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIQFNEDLVHPTRTRHGHPAFLCYIDLYVTIESDDILHNVNIPPKSFLLVQNDQYVESEQVIAEIRAGTSTLNFKERVRKHIYSDSEGEMHWSTDVYHAPEFTYGNVHLLPKTSHLWVLSGKPYRSSVVPFSLSKDQDQMNTHSLSFEQIYISNPSVTNDQVKDKLSDSFSKKEDRITDYSELNRIGHCNLIYPAKNLDLLAKKRRNRFIIPFQGSQERKKELMSLSGISIEIPINGIFRKNSIFAYFDDPRYRRKSSGITKYGTIEMHSIVKKEDLIEYRGVKEFRPKYQMKVDRFFFIPEEVHILAGSSSIMVRNNSIIGVDTWITLNTRSRIGGVVRVERKKKKIELTIFSGDIHFPGETDKISRHSGILIPPSRKNSKDSKNLKKWIYVQRITPTKKKYFVLVRPVVPYEITDGINLATLFPQDLLQERDNVQLRVVNYILYGNGKVTRGISDTSIQLVRTCLVLNWNQDKKGSSIEEARGSFVEVRTNGMIQDFLKVNLVKPAISYISKRNDPSSEKKEGSDHTNMNPFYSIYIYPKTKLQKSFNQNQGTVRTLLGINKECQFFLILSSSNCFRIGPFKGVKYPKELIKKDPLIPIRNSFGPLGTALQIANFFSFYYLITHNQILVTNYLQLDNLKQTFQPFKFQYYLMDENGRIYNPDPCSNIIFNPFKLNWYFLHYHFCEETSTKIDLGQFVCENVCITKKGTHLKSGQVLIVQFDSVVIRSAKPYLATPGATLHGHYGEIIYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISINLEKRIDSWNERITRILGSPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNVFLPGELIGLFRAERTGRALEEAICYRATLLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGFVHHSSQHKDIPLKTKKQNLFEGEMGDILFYHRELFESCLSKN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HSLV_HELPY
Sequence: MFEATTILGYRGELNHKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTADAFSLFDMFERILESKKGDLFKSVVDFSKEWRKDKYLRRLEAMMIVLNFDHIFILSGMGDVLEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEESLKIAGDLCIYTNTNIKILEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP57_HUMAN
Sequence: MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLETNRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY
What is the function of this protein?
Centrosomal protein which may be required for microtubule attachment to centrosomes.  May act by forming ring-like structures around microtubules.  Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.
What are the official names of this protein?
Centrosomal protein of 57 kDa, Cep57, FGF2-interacting protein, Testis-specific protein 57, Translokin.
What is the protein family that this protein belongs to?
Belongs to the translokin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: AROC_BRUSI
Sequence: MSHNSFGHLFRVTTWGESHGLALGCVVDGCPPGITFTEAEIQSFLDKRKPGQSKYTTQRREPDQVRVLSGVLLGEDGVTMTTTGTPISMMIENTDQRSKDYGEIARQYRPGHADYAYDVKYGIRDYRGGGRSSARETAARVAAGAIARKVVPGLEVRGALVSIGAHDIDRSRWNWAEVDNNPFFTPDAGSVEVFADYLDGIRKNGSSVGAIIEIVAEGVPAGIGAPIYGKLDQDIASYLMSINAVKGVEIGNGFEAARLTGEENADEMRMGNDGKPIFLSNHAGGVLGGIATGAPVVARFAVKPTSSILTPRRSIDKDGNEVDVMTRGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGRV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FLUP_ASPFN
Sequence: MEANDSPHDVAVVGMGCRLPGNNNTPEELWRSILQKVDASSEIPRMRWEPYQQNAQNARSIGKVPRRGYFVKNLENFDAGFFNISPKEAEQMDPQQRLVLEVTWEALENAGIPLSSLSGSDAAVFMGVNSDDYGKLLLEDLPHVEPWMGIGTAYCGVANRISYHLNLMGPSTAVDAACASSLVAIHLGRQAILSGESKVAIVGGVNAIFGPGLTSVLDKAGALSSDGRCHSFDDAASGYGRGEGAAVVILKNMAEAVKDGDHILATLKGTAVAQDGRTNGIMAPNQKAQELVARKALDVARVDASTIDYVEAHATSTPVGDPTEVSAISAVYGKGRSPDKPCYIGSVKPNVGHLEAGAGAVGFIKAVMSVQKGILPPQANLKTLNTRVNWSEGVQVVQDIEDWPSSGYPRRAGVCSYGYGGTVSHAIIEKYIQTGPAIYSKEQWPKGTQVLLLSSPQRRSLETQAATQAEWMSTVGKQNDLRCVAATLGTRRSHHKYRAAFVVESHDDAAEKLNAFACQTPTKWTTSGGKPEGDDRPVVWVFSGHGAQWTDMAKDLLQYRVFRDVIESVDILVQKEMGFSAIQAMEMGVLNGSDQVQVLTYLMQIGLSEVLRSLGVSCGAVIGHSVGEIAASVAAGCITPAEGTLIVTRRAKLYRRFMGAGGMALVCAPLEQITIEISTQNVNNLVVAINSSPSSCVVSGPKEEIEAFALNLNNKGIKTIHVDTDIAFHHPMLGELMEPLAEALVGYVSPSQSKVAIYSTSASDPRSTMDRGIRYWLDNMVNPVQLTSAISAAAEDASPLAPIIKKILSMESRGATIQAIAIDISSHDAASQLSSRIDDLCFPPIRGVVHAAGVLHNEHVLSVTPDSFERVLAPKIAGSLTLNMLFPPKTVDFMVLFSSCGQFFGFPGQASYASGNAFLDALATYRRSQGDNTIAMQWTSWREIGMAAGSEFVRAELATKGITDISQEEAFQAWMHVSKYDVDHAVVLRSRALEKHEPLPSPLLVDIAIHKISSILTPPPTPPLSASSDLLPLPRNPADRFDSLSRQVRECVANVLQMETDEVASQEPLSNMGMDSVMTVHLRGRLQKSLGVLVPPNLTWSHPSIDHIVKWLMEKTNDKE
What is the function of this protein?
Polyketide synthase; part of the gene cluster 41 that mediates the biosynthesis of an extracellular and diffusible metabolite that is able to stimulate colony sclerotial production (PubMed:27647242).
What are the official names of this protein?
Cluster 41 polyketide synthase.
Protein: AT1A3_CHICK
Sequence: MGDKGEKESPKKGKGKRDLDDLKKEVAMTEHKMSIEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDEPSNDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQLNAEEVVVGDLVEVKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVIATGDRTVMGRIATLASGLEVGKTPIAVEIEHFIQLITGVAVFLGISFFVLSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSATWVALSHIAGLCNRAVFKGGQENVPILKRDVAGDASESALLKCIELSSGSVKVMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHFYLPEEQYPKGFAFDCDDVNFATDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDMSSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIRGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRSDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPSCLVGIRLSWDDRTINDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS5_SHISS
Sequence: MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL82_ARATH
Sequence: MGRVIRAQRKGAAGSVFKSHTHHRKGPAKFRSLDYGERNGYLKGLVTEIIHDPGRGAPLARVAFRHPFRYMKQKELFVAAEGMYTGQYLYCGKKANLMVGNVLPLGSIPEGAVICNVELHVGDRGALARASGDYAIVIAHNPESNTTRVKLPSGSKKILPSACRAMIGQVAGGGRTEKPLLKAGNAYHKYKAKRNCWPVVRGVAMNPVEHPHGGGNHQHIGHASTVRRDKSAGAKVGQIAARRTGRRRGAAATLAAKADY
What are the official names of this protein?
60S ribosomal protein L8-2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.