PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_KORVE
Sequence: MITDALHQIVVHRRDLTREQARETMADVLGGKTTDAQIGALLVGLQMKGETVDEIVGFAEAIRAAATPLIVRDSALDVSGTERDALLDTCGTGGDASGTFNISTATALVVAGAGVKVAKHGNRSVTSKCGSADVVEALGVNINLPAERMAECLEKVGIAFLFAPAMHTAMKYVQPARRELKMRTVFNLLGPLTNPANASCQVVGVYTGQLVEKLAQALLQLGLKRALVVHGWDGLDEITISGPTKVAEVRDGKVTSYEISPEQFGLQRAPLSALEGGDAQVNAAIIRAILDGERSPKRDVVLLNAAAALVAAGQAETMGAAIPVAAYAIDSGQAKGRLRLLVEFTNL
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CLPS_XYLFT
Sequence: MSQKTVHDQDNALLLETGNTKVAPPPRYQVLLLNDDYTPMDFVIVVLQQFFAMDLKKATQVMLHVHTRGRGVCGFYTREVAESKVAQVNEFSRIHQHPLLCTMKQA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PHO1_ARATH
Sequence: MVKFSKELEAQLIPEWKEAFVNYCLLKKQIKKIKTSRKPKPASHYPIGHHSDFGRSLFDPVRKLARTFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKVNQFHKPKETEFLERGEILKKQLETLAELKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGELSEIQSETSRTDEIIEALERNGVSFINSATRSKTKGGKPKMSLRVDIPDAVAGAEGGIARSIATAMSVLWEELVNNPRSDFTNWKNIQSAEKKIRSAFVELYRGLGLLKTYSSLNMIAFTKIMKKFDKVAGQNASSTYLKVVKRSQFISSDKVVRLMDEVESIFTKHFANNDRKKAMKFLKPHQTKDSHMVTFFVGLFTGCFISLFVIYIILAHLSGIFTSSDQVSYLETVYPVFSVFALLSLHMFMYGCNLYMWKNTRINYTFIFEFAPNTALRYRDAFLMGTTFMTSVVAAMVIHLILRASGFSASQVDTIPGILLLIFICVLICPFNTFYRPTRFCFIRILRKIVCSPFYKVLMVDFFMGDQLTSQIPLLRHLETTGCYFLAQSFKTHEYNTCKNGRYYREFAYLISFLPYFWRAMQCVRRWWDESNPDHLINMGKYVSAMVAAGVRITYARENNDLWLTMVLVSSVVATIYQLYWDFVKDWGLLNPKSKNPWLRDNLVLRNKNFYYLSIALNLVLRVAWIETIMRFRVSPVQSHLLDFFLASLEVIRRGHWNFYRVENEHLNNVGQFRAVKTVPLPFLDRDSDG
What is the function of this protein?
Inositol polyphosphate sensor that associates with transcription factors to regulate inorganic phosphate (Pi) starvation responses (PubMed:27080106).  Probably acts by binding inositol polyphosphate via its SPX domain (PubMed:27080106).  Acts as a Pi exporter, mediating efflux of Pi out of cells (PubMed:21309867, PubMed:22449068).  Transfers Pi from the epidermal and cortical cells to the root xylem vessels (PubMed:11971143).  Involved in the transfer of Pi from roots to shoots (PubMed:11971143, PubMed:17461783).  Involved in abscisic acid (ABA) induction of stomatal closure and ABA repression of stomatal opening (PubMed:22612335).
What are the official names of this protein?
Phosphate transporter PHO1, Protein PHO1, AtPHO1.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In transgenic plants, relocates partially to the plasma membrane in the presence of high extracellular Pi.
Protein: I1B1_CONEP
Sequence: MKLCVTFLLILVILPSVTGEKSSKRTLSGAALRGDWGMCSGIGQGCGQDSNCCGDMCCYGQICAMTFAACGP
What are the official names of this protein?
Conotoxin Ep11.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_FRAAA
Sequence: MIPDPRDVILRPVVSEKSYGLLDENVYTFIVHPDANKTQIKLAVQQIFSVRVLRVNTINRQGKRKRTKHGWGHRSATKRALVSLAPGDTIEIFGGPGA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: KLC3_HUMAN
Sequence: MSVQVAAPGSAGLGPERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEAAAGAAGMKRAMSLNTLNVDAPRAPGTQFPSWHLDKAPRTLSASTQDLSPH
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa (By similarity).  May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece (By similarity).
What are the official names of this protein?
Kinesin light chain 3, KLC2-like, kinesin light chain 2.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Mitochondrion. Note=In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids.
Protein: GATB_WOLSU
Sequence: MFETVIGLEVHVQLNTKTKIFCSCATSFGEEPNKNVCPVCLGLPGALPVLNGEAVKKAVSFAKAVNAKVNQNSIFARKNYFYPDLPKAYQISQFEIPIVGKGWLDIEVDGEKRRIGITRAHLEEDAGKNIHEGEISKVDLNRACTPLLEIVSEPDMRNSDEAIAYLKKLHSIVRYLEISDANMQEGSFRCDANVSIRPKGDEKLYTRVEIKNLNSFRFIQKAIEYEVERQIEAWQEGVYAKEVVQETRLFDTDKGVTRSMRGKEESADYRYFPDPDLLPVFIDATLMEEAEKIPELPDEKRARLVRDFGLKEYDAGVIVADLEMARFFETMLSEGASAKGAVTWLTVELLGRLKGESGVQNSPVDAKRLACLVKRIEDETISGKSAKEVLDVLVAEGGEVDAIIERLGLKQVSDDGAILSVIDEVLAQNGDKVAEYKSGKDKLFGFFVGQVMKSAKGVNPAKVNDLLKSRLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: EFG_XANOR
Sequence: MARTTPIERYRNFGIMAHIDAGKTTTSERILFYTGVSHKIGEVHDGAAVMDWMEQEQERGITITSAATTAFWSGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYSVPRMAFVNKMDRTGANFDKVVEQLKARLGAYAVPMQVPIGAEDGFEGVVDLLKMKAIHWDTASQGTTFEYSDIPAELVDVATDARSFMVEAAAEASEDLMDKYLNEGDLSEEEILKGLRERTLKVEIVPVFCGSAFKNKGVQAMLDGVVHLLPSPADRPPVQGIDEDEKEDTRAATDTAPFSALAFKIMTDPFVGSLTFFRVYSGTLNSGDQVYNPVKSKKERVGRILQMHSNNREEIKEVRAGDIAAAVGLKDVTTGDTLCAQDKIITLERMVFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHAKQSGGKGQYGHVVIELSPMTEEDRKSDNVKDDFLFINDITGGIIPKEFIPSVEKGLRETITSGPIAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKASPVLLEPIMKVEIVSPEDYLGDVMGDVSRRRGVLQGQDDSPSGKIINAMIPLGEMFGYATSLRSMSQGRATFSMEFDHYEEAPANIADAVTKKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP1_POVSM
Sequence: MPLKKRSASAPRKTPQEVPRLLISGGVEVLGLKTGPDSITEVEAFLNPRMGLENTDNHYGYSENVTVAKKKDDDKPLKNQLPCYSVAKIELPMLNEDLTNDTILMWECISVKTEVVGINTLVNTHSYGKRDGESPSMPIVGLNYHFFAVGGEPIEMQYIVQNFQCDYPVGVVAMKPSPLSTQVLDPKQKSKLTGDGIFPIECWAPDPSKNENARYFATYTGGLNTPPVLNITNTVTTILLNENGVGPLCKGDQLHIAAADICGFHIEEDNKYKYRGLPRYFKLVLRKRVVKNPYPVSTLLNTLFTQMSPNVQGQDMTKQVEEVKIYEGTEKLPGDPDMIRFRNQFGQEETVIPVITN
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with sialic acids on the cell surface to provide virion attachment to target cell.  Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YEGH_ECOLI
Sequence: MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRDRARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKATMELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAAVVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVDHGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHTRLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFRNARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHRVQKVQIIPLRKDGEMEYEV
What are the official names of this protein?
UPF0053 protein YegH.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATA_THEVB
Sequence: MNVFGIGLPELIVILVVALLIFGPKKLPEIGRSLGKTKRAFEEASREFQDEIKRQTAALEEEQQAKAEAESPREISP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PGK_CAMC5
Sequence: MSDILSISELNLAKKRVFIRCDFNVPMDEFLNITDDRRIRSAIPTIRYCLDNGCSVVLASHLGRPKSGFEEKFSLKGVAKRLSRLLDRDVIFANDVIGSDAQNKASALKSGEILMLENLRFEKGETKNDEILAGELAKFGEIYINDAFGVCHRAHASVEAITKFYDDEHKAAGFLLQKEINFAQNLIKKPTRPFVAVVGGSKVSGKLQALHNLLPRVDKLIIGGGMAFTFLKSLGENIGNSLLEEELIDDAREILKKGKELGVKIYLPVDVVAAQSFSAESAVKYVTVQEIPSGWMGLDIGPASVRLFKEVLADAQTVWWNGPMGVFEMDKFSKGSIKMSHAIVETHATTVVGGGDTADVVERAGDADEMTFISTGGGASLELIEGKELPGIKPLRKASE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_YERP3
Sequence: MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL4_METHJ
Sequence: MKAQVLTLTGSVAHEIELPPVFSSEFRPDLIKKAVIAQQSRRYQPHGAYVYAGITASAVGWGSGRGVSHVPRLKNSSRAAKVPQAKGGREAHPPKVEKVLIRNINQKEKRKALNSAIAATISPELVRSRGHVFTGSLPYVLSGDFESLKKTKEVIAALRAVGVYGDVERAERSRKVRAGRGKLRGRRYKQRKSLLIVTGKERLRAARNLAGVDVCLVDNLNVELLAPGTHSARLTLWTEDAVRKLGGEQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYI_STRP6
Sequence: MKLKETLNLGKIAFPMRADLPNKEPQWQAAWEQAELYKKRQELNAGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIEQVLAKQGIKRKEMNLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFEADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGKGILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGKFGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGEDDYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINHSYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGFTHPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSSLITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVASVDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMTIVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRRMQTVFYDILVKITKLLTPILPHTTEEIWSYLEYESEAFVQLAEMPVAETFSAQEDILEAWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIVSQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAKIIEENFPEAVAEGFEESGK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_BRUA1
Sequence: MSRIGKKPVPVPAGVTGSVEGQTVKAKGAKGELSFVVHDEVLVKMEDGAVRVDPRDQSKEARSKWGMSRTMISNIFVGVKDGFEKKLEISGVGYRAAMQGKNLQLSLGFSHEVVYDVPAGITVAVPKPTEIVVTGIDKQQVGQVAAEIREYRGPEPYKGKGVKYAGEKIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RECR_BURP1
Sequence: MSIKPPSALSELVEALRALPGVGPKSAQRIAYHLMQHDREGAERLGRSLLFATEHLRHCEKCNTFTEAQICEVCSDPERDPALLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGIVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MRAZ_BURVG
Sequence: MFQGASALTLDAKGRMSVPARYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYIAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TPM2_RAT
Sequence: MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells (PubMed:7568216, PubMed:22812662).  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:22812662).  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.  The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity).
What are the official names of this protein?
Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers (PubMed:7568216).
Protein: RL4_SHESM
Sequence: MELVLKDAQSALEVSETTFGRDFNEALVHQVVVAYAANARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGGVKGPIWRGGGVTFAAKTQDHSQKVNKKMYRGALKSILSELVRQDRLVVVESFSVEAPKTKELKAKLKAMNLEDVLIVTAEVDENLFLAARNLYKVDVRDVAGLDPVSLIAFNTVLVTADAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DGTL1_NITEU
Sequence: MRSNLAPYAVSDTNSRGRRIHEELPAGRSQFQRDRDRVIHSTAFRRLEYKTQVFVNHEGDLFRTRLTHSLEVAQIGRSIARNLNLNEELVEAITLSHDLGHTPFGHAGQDALNDCMKTYGGFEHNLQSLRVVDVLEERYATFNGLNLCFETREGILKRVPKSKAAALDELGTRFLHGHSASLEAQLANLADEIAYNNHDVDDGLRSGLITLAQLEEIEIFARHLHQVKQHYPDITGRRLIHETVRGMINTLVVDLTVQSGTRIRDASPDSPDSVREKPVLIGFSDTIKRQQQELKRFLHKNLYKHYQVMRMSNKARHTIEKLFTTFETEPALLPYEYQQKFQEYGHQAIADYIAGMTDRYAIREYQRLFAITEN
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: PANC_BORPA
Sequence: MKVVHTIQDLRDHLRGQNRVAFVPTMGNLHEGHLALMKLARQHGDPVVTSIFVNRLQFGPNEDFDRYPRTLPDDVAKMERDRDVYLVFAPDEREMYPEPQNYRVLPPDDLGDILEGEFRPGFFTGVCTVVMKLLACVQPRVAVFGKKDYQQLMVVRNMCRQLQLPVEILAHETVRADDGLALSSRNRYLSEAERAEAPVLYETLRGIAQRRAGGEQDPAALERVAAQALADRGWKVDYVAVRRQRDLKAPDVAEMSAGEPLVALAAAKLGATRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLAG_HUMAN
Sequence: MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
What is the function of this protein?
Likely does not bind B2M and presents peptides.
What are the official names of this protein?
HLA class I histocompatibility antigen, alpha chain G, HLA G antigen, MHC class I antigen G.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Early endosome membrane. SUBCELLULAR LOCATION: [Soluble HLA class I histocompatibility antigen, alpha chain G]: Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 5]: Secreted. Early endosome. SUBCELLULAR LOCATION: [Isoform 6]: Secreted. SUBCELLULAR LOCATION: [Isoform 7]: Secreted. SUBCELLULAR LOCATION: Cell projection, filopodium membrane. Note=HLA-G trogocytosis from extravillous trophoblast's filopodia occurs in the majority of decidual NK cells.
Protein: OBP1_SCHPO
Sequence: MPNPNQAIKKENEPIQVENPTELVRDDGEVEGYQKEEGKFKLVLSILKQCIGVKDIASLRFSLPAQLLEPVGNLEYWNYVDRPDYFAVMGDSDDELERMLGVLRWWFTKDLRFVRGRVVKPYNSVLGEFFRCKWVVTDPTVREDHTLDPDSSQLPTYKTEYSETTKFPLGKSYRPKASRTTSSQSVASTMTKSSTKTSKKKSSKKNSKSESNQDSSNDRSSTAPSTAESNNEHLSSSQKSKHSIVFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAVGFTGTSFKVCAGDLNKGVYVRFNKRDNEEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIKTIITYIEERWLGKPRSLVEGVCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESESRMLVDLNELDLVHKRCPPLDKQFPFESRKIWFPVTHNILAKHYTQATKAKQEIEDQQRQASAAREESHTEWKPRFFVPDEKEGRPTLTEEGKKVLEQSLSDEYIHGS
What are the official names of this protein?
Oxysterol-binding protein-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: CCAP_SPOER
Sequence: PFCNAFTGC
What is the function of this protein?
Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude.  The effect of CCAP is both ino- and chronotropic.
What are the official names of this protein?
Cardioactive peptide, Crustacean cardioactive peptide, CCAP.
What are the subcellular locations of this protein?
Secreted.
Protein: YRAN_SALPC
Sequence: MAQIPARGDCSRQLTRKQAGDAWEAAARRWLESKGLRFIAANVRERGGEIDLIMRDGKTTVFVEVRYRRSGLYGGAAASVTRSKQHKLLHTARLWLARQNGSFDTVDCRFDVLAFTGNEIEWFRDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.