PharMolix/UniProtQA huggingface dataset:
Protein: IF2_HELPY
Sequence: MSGMVDLKEFLAELGKTQKELKNVIEQAKDIGLELKTNSKMTPEQAGKLYKYIVDGIKEQIQANQPAKNPEQDNKDDLNTAVASKSLNKKVSKTPKKEETKSQPKPKKTKEKKKEAPTPIAKKKGGIEIVNTFENQTPPTENTPKVVSHSQIEKAKQKLQEIQKSREALNKLTQSNANNASNANNAKKEISEVKKQEQEIKRHENIKRRTGFRVIKRNDEVENESENSVTESKKPTQSAAAIFEDIKKEWQEKDKQEAKKAKKPSKPKATPTAKNNKSHKIDFSDARDFKGNDIYDDETDEILLFDLHEQDNFNKEEEEKEIRQNINDRVRVQRKNPWMNESGIKRQSKKKRAFRNDNSQKVIQSTTAIPEEVRVYEFAQKANLNLADVIKTLFNLGLMVTKNDFLDKDSIEILAEEFHLEISVQNTLEEFEVEEVLEGVKKERPPVVTIMGHVDHGKTSLLDKIRDKRVAHTEAGGITQHIGAYMVEKNDKWVSFIDTPGHEAFSQMRNRGAQVTDIAVIVIAADDGVKQQTIEALEHAKAANVPVIFAMNKMDKPNVNPDKLKAECAELGYNPVDWGGEHEFIPVSAKTGDGIDNLLETILIQAGIMELKAIEEGSARAVVLEGSVEKGRGAVATVIVQSGTLSVGDSFFAETAFGKVRTMTDDQGKSIQNLKPSMVALITGLSEVPPAGSVLIGVENDSIARLQAQKRATYLRQKALSKSTKVSFDELSEMVANKELKNIPVVIKADTQGSLEAIKNSLLELNNEEVAIQVIHSGVGGITENDLSLVSSSEHAVILGFNIRPTGNVKNKAKEYNVSIKTYTVIYALIEEMRSLLLGLMSPIIEEEHTGQAEVRETFNIPKVGTIAGCVVSDGVIARGIKARLIRDGVVIHTGEILSLKRFKDDVKEVSKGYECGIMLDNYNEIKVGDVFETYKEIHKKRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDCI_ECOLI
Sequence: MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGRSLHRKEGLNNDVVRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSDPELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDALVQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGAGEPIGILTRVDATFSSGCQLMINAIRKSMPF
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdcI.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PANC_SHEWM
Sequence: MITTQEIQQIREQIRTWRTKGETIAFVPTMGNLHLGHITLIKEAAKRADHVVASIFVNPMQFGANEDLDAYPRTLEADKLALSDAGAELLFTPTPDIIYPKGMEQQTYVEVPKIGDQLCGASRPGHFRGVATVVCKLFNIVQPDIALFGRKDFQQLMIIKTMVEDLSLPIEIVGIDTIRETSGLAMSSRNGYLSTAQKSQAAVLKQTMDQISSAVKQGASLDLAIENGKQALIDSGFTPDYLELRNAKDLSLVTDGQDELVILAAAYMGNTRLIDNLCFTR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_DESAP
Sequence: MSSRNWTGPQEAAIGCREKNLLVAAGAGSGKTAVLVERVIRRISDPAAPVDVDRLLVVTFTNAAAAEMRKRVAEALERELEKHPGMPLLEHQLRLLPQADITTIHSFCAELLRRYHYLIDLDPEFRVADETEAAILRQETLEEFFEEQYRVITGDPDLEFLVEAYGGERDDLKLQNLVSGLHRFARSNPWPEAWLARAAAFGADPQGLDGDGPLAWGLRDLVGTGLEAAVFELRAALEAAKAPGGPAVYADALAAEVEGTARLAGLVAGDWEPLRAAFLAFGFTPRLPAARAGVDQELKDLCSRCRKKAKERIQNLKETFFARRPEELLSEMAALGPAMRRLAALAADFGEAYRTAKLARNLVDFADLEHYCLQILLAPGSTPEAPVPSPVAAGLREYYVEVLVDEYQDINAVQETILRLVSRQDAAAPNLFMVGDVKQSIYRFRLAEPALFLEKYRAFDTGEDAGGARRIDLSHNFRSRESIIHAVNAVFRRIMTPAVGELAYDTAAELVCGGTPAQLEGSGPPVEVHLLGAPTSVGRDTAGTADDEPDRSDEADLTAVQREARLVAGIIRRLAGLGGECTVPYRDIVVLMRATTGKAGTYLEEFRRQNIPAYAKVGTGYFEAVEVETVLSLLKVIDNPHQDIPLAGVLRSPLVGLGAAELAAVRLADKEGDFFRAVVAAAGQGGRLGAVLAGFLERLEKWRSQARCGSLADLIWDVYRTTGYYDYVGGLPGGAGRQANLRALYDRARQYEATAFRGLFRFLRFIELLQEGGQDLGPAPALAESENVVRIMSIHQAKGLEFPVVILADMGRRFYMPDLNGEVLLHKDLGLGPYFVDPGARVSHPTAAWHVVRERLRREQLAEEMRILYVAMTRARERLILTGSAGRLEQAVLRWSHAAAGDGETLPVPVLAEAESFLDWVMPVLMAHPDGEPLRRLAVRSRPAAGTPKDRSRWEVHLHRPEDLEEAAGADPDTAAVLESLRRLAPIPADGGLDEAVHRALSWHYPWSALASCGAKISATEVKRRFAAAAAGEEEVPAVFPYRAPPARPAFLETARGLSPQAFGRAMHVVLQHLDLAGDLSVDGIRAQVAGLEEREFLTATEARAIDAEKLAGLFAGGLGRRLAGALWVRREWPFCLVVPAHEIYPGLEGHPEERVMVQGIIDCLFAEPDGLVLVDYKTDRVGPGGEAALADRYRGQLDLYARAVEAVLRRRVKERYLFLVMTGSAQIIQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: CINAL_ECOSE
Sequence: MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVGDNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMERYFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVMVEHEILPRLRERFSLPQLPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPIIELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQFTGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEHLNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEVIESMTLSV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ZN334_HUMAN
Sequence: MKMKKFQIPVSFQDLTVNFTQEEWQQLDPAQRLLYRDVMLENYSNLVSVGYHVSKPDVIFKLEQGEEPWIVEEFSNQNYPDIDDALEKNKEIQDKHLTQTVFFSNKTLITERENVFGKTLNLGMNSVPSRKMPYKCNPGGNSLKTNSEVIVAKKSKENRKIPDGYSGFGKHEKSHLGMKKYRYNPMRKASNQNENLILHQNIQILKQPFDYNKCGKTFFKRAILITQKGRQTERKPNECNECRKTFSKRSTLIVHQRIHTGEKPYVCSDCRKTFRVKTSLTRHRRIHTGERPYECSECRKTFIDKSALIVHQKIHGGEKSYECNECGKTFFRKSALAEHFRSHTGEKPYECKECGNAFSKKSYLVVHQRTHRGEKPNECKECGKTFFCQSALTAHQRIHTGEKPYECSECEKTFFCQSALNVHRRSHTGEKPYECSQCGKFLCTKSALIAHQITHRGKKSYECNECGKFFCHKSTLTIHQRTHTGEKHGVFNKCGRISIVKSNCSQCKRMNTKENLYECSEHGHAVSKNSHLIVHQRTIWERPYECNECGRTYCRKSALTHHQRTHTGQRPYECNECGKTFCQKFSFVEHQRTHTGEKPYECNECGKSFCHKSAFRVHRRIHTGEKPYECNQCGKTYRRLWTLTEHQKIHTGEKPYECNKCEKTFRHKSNFLLHQKSHKE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 334.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y064_MYCGE
Sequence: MLNLIKNVIRSLKSAKIALIALTFLIFVAVGGFVLLNNTVNNFNAAFNYVTHTGKLSNAIINERYDFGKLEFQEQTNNSQNSSDSFTLTLTNDSRTSFINNALRTNPSLYEGLVTQTFSYQNKTEMTEKTNIVNQSKIIAANNLNNALSKDKQLLVSGQLEKLNAVFREYKAINITDKSVFKKLIVSEPNDLVNSLVIFDGQNLSSSKQSDFNNFLNQFNEIKSKGKDNLSTTLKTGQYQAFLQTLFDYAQASETTLKDQLQKLISNPDSSETNQVKNLFDTPSTLTNIGGQLTLQWTENSLTKQIVIFDPSSYETIVAPGNWTYQQQLGKEVYPDINNWESIKKLPLEQFESEFLKIDQKYKISIDNIDYLVIGVGISPDFVYPVFSASLIVPNIENEQLYYVNQTGYERTFSSFLTNPVETAIVARLINLESDLNTINQWAVENMSWPTNIKAAYSSSDTTNILNLLAARTVFIPNLINTINLVALFLTIAILTVAIIVSILILISYLKKNTEQIGILKANGLSGKKINLSLLIFGLIPAIVGAISGYSFGIGFQDVAIHLFSNYWFIPTATSSFSVVGLLFFSLFVILIMSSISLLVGSIILKKDVVKILKHDSEFKVSRLGLSSKKLFARFGIMTRFRVALAFNAPWKLVFLTLMSSFTMMILNLSFATKDSFENAQSKTNLTNQNHQYEFELASATTQSGLLKWQLFAELGTTDKRSESSVKLANKRMDISNVDASKDWKNQQVINFLSDASGFSNDLNYLENIVQSKIGLDYSLGFNNIVSNPWRLSETLMPTNQASASNTAFQNFLKAIITINPSQGSQFIKQTQDPLTKRFIYAIDSDKALKNNNEQNGSQNHLTLNDDFAKFLYSQFELIKKSGNASNEDLNAIDFENPQTIRDFYNKYNALPPLDYKLSFNVIGLPKETIAGQIDTPKYGFLTLHGEYQNTPIKIKGIKDWKDKVDNLGPVLSDQNNHIINQELFKNYSFDPLIVNNSAAKKYQLAIGSEINIAVNNSFKRIDNKIINQDPLVNATFRVVGINNSAHDPEFFTSYSTAFKVLEYPNEWFVKKLPFNSFYANSLLSFVQSTSLFSESGIFPATSSFSTNNTVLVELIKKTINYKNGQMNQTSSNDSSKKENYQKLQKALGISTDLEISKVNEYVAILARVYNGLPYNSTISFISNVAANNALFGNIANTTKQIQAVVIAVIIPIIMLIILLVSTTLIQELKKIAIRLKALGYSNLKILASFLSIYIPLFAFGLLISIPFSIYLIALHNEVIFASSSIFLDAFLSFESAIGSMLVLLAVLSITFVLNWLELNKIKIDKEIKNS
What are the official names of this protein?
Uncharacterized ABC transporter permease MG064.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FIBB_HORSE
Sequence: LDYDHEEEDGRTKVTFDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_LYSSC
Sequence: MNEIEQRIAELNKLLHEYGYAYYVLDKPVVADSVYDQLLHELIALEEANPSLIFPDSPTQRVGGTVVEGFKKVTHDYPMLSLSNAFNEADLQEFDRKVRQAIGDHFSYVCELKIDGLAISLKYENGVFVQGATRGDGVVGEEITANLKTIHAIPLRLKEPITIEVRGEAYMPKKSFEKLNAQRADNGEELFANPRNAAAGSLRQLDPKIAASRQLSTFIYAIGGDGEIYGIDGHAEMLDYLEDLGFPSNKERQRCSTIEEVMAFIEHWTENRPHLAYEIDGIVIKVDRYAQQDELGYTAKSPRWAIAYKFPAEEVVTTLLDIDLTVGRTGVVTPTAILTPVQVAGTTVQRASLHNEDLIRDKDIRLGDTVIIRKAGDIIPQVVGVLIEQRPENSVPFEMPKNCPVCDSELIRIEGEVALRCVNPACFAQIAESIKYFVSRNAMNIDGLGDKVVEQLLRADLIHDVSDLYHLTIEQLVELERMGEKSATNLVNAIQASKENSMERLLIGLGIRHVGEKAAKIVSEQFGSMEAVMAATEEQLVAIYEIGDKMASSLVEYFSNDDARAVIERLAEVGVNMTFKGKKVEVVVGDNPFAGKTIVLTGKLEQLTRNEAKAKIEELGGTVTGSVSKKTDLVIAGEDAGSKLAKAEQLGIEVWNEDNLIEQLNLI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ERB1_YARLI
Sequence: MVRSRSNSVKKDLKRKVDEPVDVQDEFDVEGLIDEGDSDDEDEAEQEVAQENVTKDKKNTSKTENEEDADDESDSDAELEALIGEEEDLSGSELEDELAYFSDAGDDEVDPSILKHLDDGVRLRSLSRSSDQTDELKDVVEIVPGADGKPRMIKKEIHAVYDSDDSDQEESNTIGNVPLSAYDQMPHIGYDINGKRIMRPATGSALDNLLETIDLPEGWTGLLDKSTGKGLNISKEELELIKRIQKNETTDDASNPYEDLVEWFSSKTEIMPLSAAPEPKRRFIPSKHEAKRVMKMVQAIRQGKLLTKPKEDPDARPNYDVWADNLTDVQDHVMTLRAPKMPPPTHDESYNPPAEYLPTEEEIAEWNALAPSERERNYVPKKYTALRHVPGYSESVRERFERSLDLYLAPRVRKNKLNIDPDSLIPDLPSPKDLMPFPIRCATTYKGHKGKVRAISVDPSGEFLATGGDDGTLRVWEVLTGRELYRCRLVASIDAQDDSVECVQWNPAVPGMLAASAGEHIFLIVPPTLFDFDIENTGREKIEQGWGFAEGGREQQDIDTKGLDDDADSDSDDETGHVKKKSPPAKWITPTAKQQASGIGAIITATKTIKRLAWHRKGDYLVTVAPSAQHRAVAIHQISKHSSQSPFNKSKGIVQDAMFHPFRPHLYVATQRYVRIYDLAKQVMAKKLMPGARWVSSLDIHPRGDNVILSSFDKRLLWHDLDLSDKPYKTLRYHEKAVRHAAFHKGGLPLFCSASDDGNINIFHGTVYDDMMTNPLLVPLKVLKGHDVKSGLGILRVEWHPREAWLFSAAADGTAKLWTT
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: MASTI_POLPI
Sequence: IDWKKLLDAAKQIL
What is the function of this protein?
Chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to rat erythrocytes and no mast cell degranulation activity at physiological concentrations.  Potent antimicrobial peptide against Gram-positive bacteria B. subtilis CCT 2576 (MIC=4 ug/ml), and S. aureus ATCC 6538 (MIC=15 ug/ml) and Gram-negative bacteria E. coli ATCC 25922 (MIC=8 ug/ml) and P. aeruginosa ATCC 15422 (MIC=8 ug/ml).
What are the official names of this protein?
Mastoparan-1, Mastoparan I, MPI, Polybia-MPI, Venom protein MP-1.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_SALG2
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQRQLEEALNVLLEEVRVNPQQILQSDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKETVRELLTANRQLQSALVETAQANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEALPLADLQKFSHVIGDDVYPMLSLQSCLDKRAAKGGVSPQQVAQAIDDARARLAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1R8_BOVIN
Sequence: MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLVLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
What is the function of this protein?
Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1).  It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates.  May also be involved in pre-mRNA splicing.  Binds DNA and might act as a transcriptional repressor.  Seems to be required for cell proliferation.
What are the official names of this protein?
Nuclear inhibitor of protein phosphatase 1, NIPP-1, Protein phosphatase 1 regulatory inhibitor subunit 8.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Mainly, but not exclusively, nuclear.
Protein: PUR7_PYRAB
Sequence: MEVYEGKAKKMIPMDDDKFIMEFKDDATAFDGVKKAKFKGKGWLNAQISAKFFKLLEEHGIKTHFIGVAGDNKLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKSDELHDPMINYYHAKILGITLEEIKKMEEIALKVNEILKDYLAKRGIILVDFKLEFGKNKNGEIILADEISPDTCRFWDAETKKSLDKDVFRFDKGDLIEAYEELYRRITGEDPGN
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PG12B_HUMAN
Sequence: MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL
What is the function of this protein?
Not known; does not seem to have catalytic activity.
What are the official names of this protein?
Group XIIB secretory phospholipase A2-like protein, Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
Protein: GLYA_CORDI
Sequence: MTDDIRYQSLTELDPEVAAAITGELDRQRSTLEMIASENFVPRAVLQAQGSVFTNKYAEGYPGRRYYGGCENADIVEDLARNRAKEVFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLSLAHGGHLTHGMHLNFSGKLYEVAAYEVEPDNFRLDMDKIREQALKEKPQVLIAGWSAYPRHQDFAAFRSIADEVDAKLWVDMAHFAGLVAAGLHPSPVPYADVVSTTVHKTLGGPRSGMILSKQEYAKKLNSAVFPGQQGGPLMHAIVAKAVAMKIAATEEFKDRQQRTLDGAQIIAERLTGADCKAAGVDVLTGGTDVHLVLVDLRNSQMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLRIGTPALATRGFDAAGFTEVADIIATALAQGAGADTEQLRARVAKLAEQYPLYEGLEDWKLL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECM_PROMH
Sequence: MSIINFWRQFGRRYFWSHLLLGMVAAGIGMPSLVSAHAENPSQTDTPSSQNRQSQALIAFDNLFLRQSVQNPASSFTFNYWQQHAVKNVIKQLSFAFTIHSPELMVKAKDEPSPVANVAEVMLDTLYALLTQAPSSTLVNLPISRGVLTENRISYHTGLWLAQIRGIRAGPYLTA
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: IHFB_PSYIN
Sequence: MTKSDLIERLTSKHFQLSVKEVEDSVKETLTLMANSLAQGERIEVRGFGSFSLHYRAPRVGRNPKTGDRVELDGKYVPHFKPGKALRERVNAANA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: METK_HELPG
Sequence: MKDSFLFTSESVTEGHPDKMADQISDAVLDYIIERDQKAKVACETLVSNGFCMITGELKTSVYAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGVGEQSPDINQGVDREDGEIGAGDQGLMFGYACKETETLMPLPIHLAHQLTFALAQKRKDNTLPFLRPDGKSQVSVRYENNKPVSIDTIVISTQHSPEVSQKHLKEAVIEEIVYKVLPKEYLHDNIKFFVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQLAYAIGVIEPVSVYVNTHNTSKYSSAELEKCVKAVFKLTPKGIIESLDLLRPIYSLTSAYGHFGRELEEFTWEKTNKAEEIKAFFKR
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_MANSM
Sequence: MKYSVKQTALEQENKSLFIAIFENQELSPAALKLDLKLKGEITEAVKNGEVSGKIGRILVLRHGAQRIILVGCGKQNEVTERQYKQIIQKAVKTAKETIATTIINALTEVKIKDRDLYWNVRFAVETIEEDNYIFEQFKSKKSENNSKLAEIIFYTEENHEQAELAIRHATAISSGVKAAKDIANCPPNICNPAYLAEQANQLAGRSSLIETTVIGEKEMRKLGMNAYLAVSCGSKNEAKLSVMEYRNHENPNAKPIVLAGKGLTFDAGGISLKPAADMDEMKYDMCGAASVYGVMNAIAELQLPLNVIGVMAGCENLPDGNAYRPGDILTTMSGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDVATLTGACVVALGQHNSGLVSTDDNLAQDLERAAKLANDKAWRLPLSEEYQEQLKSKFADLANLGGRWGGAITAGAFLSNFTKNYPWAHLDIAGTAWLQGQNKGATGRPVSLLVQFLLNQVK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_SACS2
Sequence: MGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHBB_SHIFL
Sequence: MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIKKQQKPAQ
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA1_CUPMC
Sequence: MTRPMLEALDLAGVRGERRLFDHLTFRIVPGECLSVHGENGSGKTTLLRTLAGFATPAAGRVLWKGKPLRNQWSEYQRELVYNGHGIGLKEDLNALDNLLAAAAIAGEPVTTECVESALDEVGLAEHRHLPFRMLSQGQKRRASLARLLLYRRKLWILDEPSTALDQFGARWLGELIHRHQSRGGMVVLTSHQELALKTSQTVRMGA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA 1, Heme exporter protein A 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFTU_SHESH
Sequence: MAKEKFERNKPHVNVGTIGHVDHGKTTLTAAISSVLTKTYGGEVKDFAQIDNAPEERERGITINTSHIEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVPFIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGEPEWEAKILELAEALDTYIPEPERAIDGAFILPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKDTTKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKREDVERGQVLAAPGSITPHTTFKSEIYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVAMTVTLICPIAMDEGLRFAIREGGRTVGAGVVAEIVA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.