PharMolix/UniProtQA huggingface dataset:
Protein: UBIG_ACIAC
Sequence: MSSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGCGGGILADAMARKGATVTGIDLATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFDTVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNAKAFLLAIVGAEYVLGMLPRGTHEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: VL1_HPV82
Sequence: MALWRTNDSKVYLPPAPVSRIVNTEEYITRTGIYYYAGSSRLITLGHPYFSIPKTNTRAEIPKVSAFQYRVFRVQLPDPNKFGLPDPNLFNPDTDRLVWGCVGVEVGRGQPLGVGLSGHPLFNKYDDTENSRFANGNDQQDVRDNISVDNKQTQLCIIGCAPPIGEHWATGTTCKNVPVPQGDCPPLELVSTVIEDGDMVDTGFGAMDFANLQATKSDVPLDIAQSVCKYPDYLKMSADTYGNSMFFHLRREQIFARHYYNKAGVVGDAIPDKAYIKGTGAGRDPISSYIYSATPSGSMITSDSQIFNKPYWLHRAQGHNNGICWNNQLFITCVDTTKSTNLTISTAVTPSVAQTFTPANFKQYIRHGEEYELQFIFQLCKITLTTEIMAYLHTMDSTILEQWNFGLTLPPSASLEDAYRFVKNAATSCHKDSPPQAKEDPLAKYKFWNVDLKERFSLDLDQFALGRKFLLQIGAQRKPRPGLKRPAPSSSASSSAKRKRVKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GATB_LACJO
Sequence: MNFKSTIGLEVHFELKTKSKIFSPSPVSYGAEANTETNVIDWAMPGVLPRLNKDVYRLGIMVALATHSHVLPVTHFDRKNYFYPDNPKAYQITQFFQPLARDGYIEIEVRGKKKRIGIHEMHIEEDAGKNTHGANGYSYVDLNRQGVPLLEVVSEPDMEDPEEAYAYLTKLRQIVQFTGASDVKMEEGSMRVDTNISIRPAGQEKLGTKVEMKNLNSFDHVRRSLAYEEKRQQQVLLSGGRVQLSTRRFDEATGKTVLERVKEGDADYRYFPEPDIAPYHIKQSWIDEIEESLPESPFERRKRYVEEYGIKEYDADVILQTKESSDFYDAAVAAGADPTLAANWLNTQVNGYLNENQVGIADIKLTPEHLAEMIKMIKDGTISSKIAKKVFKESIENGTDPKKYVEDKGMVQLSDVSVLGPMVTKVVDDNPQSVEDFKNGKDRAIGFLVGQIMKQTRGKANPKVVNQLLNKELQSR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: TERL_BPSPP
Sequence: MKKVRLSEKFTPHFLEVWRTVKAAQHLKYVLKGGRGSAKSTHIAMWIILLMMMMPITFLVIRRVYNTVEQSVFEQLKEAIDMLEVGHLWKVSKSPLRLTYIPRGNSIIFRGGDDVQKIKSIKASKFPVAGMWIEELAEFKTEEEVSVIEKSVLRAELPPGCRYIFFYSYNPPKRKQSWVNKVFNSSFLPANTFVDHSTYLQNPFLSKAFIEEAEEVKRRNELKYRHEYLGEALGSGVVPFENLQIEEGIITDAEVARFDNIRQGLDFGYGPDPLAFVRWHYDKRKNRIYAIDELVDHKVSLKRTADFVRKNKYESARIIADSSEPRSIDALKLEHGINRIEGAKKGPDSVEHGERWLDELDAIVIDPLRTPNIAREFENIDYQTDKNGDPIPRLEDKDNHTIDATRYAFERDMKKGGVSLWG
What is the function of this protein?
The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction (PubMed:10930407).  The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities (PubMed:23419885).  Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine (PubMed:23419885).  The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer once the capsid is full (headful packaging) (Probable) (PubMed:10930407).  Once the capsid is packaged with the DNA, the terminase complex is substituted by the adapter (gp15) and the stopper protein (gp16) that form the connector (Probable).
What are the official names of this protein?
Terminase, large subunit, DNA-packaging protein, Gene product 2, gp2.
Protein: ALFL1_ORYSJ
Sequence: MDASYRRDGRGGGGGGGGGGSAPRSVEDIFKDFRARRTAILRALTHDVEDFYAQCDPEKENLCLYGYANEAWQVALPAEEVPTELPEPALGINFARDGMNRRDWLALVAVHSDSWLVSVAFYYAARLNRNDRKRLFGMMNDLPTVYEVVSGSRQSKERDRSGMDNSSRNKISSKHTSDVARVENNIKEEDEGYDEDDGDHSETLCGTCGGIYSADEFWIGCDVCERWYHGKCVKITPAKAESIKQYKCPSCSSKRPRQ
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 1.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_MYCBT
Sequence: MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD111_CAEEL
Sequence: MSDHLGSSHDEGELSDESHKKSQRASSSDEPNPAKSNKGLESKMRESILSRLSKRKNSESDDDTTEQRFSIQPKNAQKAKEDRYRDKERDKKREKDKRDDRRDVRGPDARQKDRDFKGRQERSGRDQKVHEHRHHHHHRKHETDGHRTNRSNRDRSSERDSEKHKRHIDRHKKSSTTSPDNDKSPHKKSKHTDVPADAKLFDRILDPNYKKKDDDVLVIEDVEMSPIEILEEKEEKEIVEFTIDSPAGPKKYSKFESDPESDHDDTKPKSPGKAEDDDDVIEVLDDALHSDDDADSDEDKYLKTPEDREWEEMTETEQRLHKEAMKKRASMKQKTLIAQLPVFYPGLMGCRNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGWKALTFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEEPYPVPPEEFPTFPAKSEQNKAPPPAKQKQQENRISHVDPETAKLLKQFEVRPEQVKPGGFSLKFDPTRF
What is the function of this protein?
Probable cyclin-dependent kinase whose activity is most likely regulated by the cyclin cyl-1/Cylin-L (PubMed:29886128).  Important for normal oocyte and sperm development; probably required during multiple stages of gametogenesis (PubMed:29886128).  Plays a role in the activation of RAS-ERK signaling in the germ line (PubMed:29886128).  Also acts partially redundantly with cdk-11. 2 to ensure embryonic viability (PubMed:29886128).
What are the official names of this protein?
Cyclin-dependent kinase 11.1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALLB_ECO81
Sequence: MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: CH60_HOLOB
Sequence: MSVKQIAFGSKVGESLLNGVIKLANCVQVTLGPNGRNVLIEQSFGDPRVTKDGVTVAKHVELEDRYENLAAQLVKSVASKTADMVGDGTTTATVLARSIYSEAFKGTSAGMNSMELRAGIDHAVEIVVEKLKELSIPVKGDYQKISQVATVSANGDTEIGDMIAQAMEKVGSDGVITVEEAKSFKTELDVVPGMQFDRGYISPYFITRQDKGIAELERSYILLYDGKISSAQSLLPVLEKCAKESASLLIIAEDVEGEALRMLVVNKLRGVLKVAAVKSPGFGDRRKAMLGDIAVLTNGYVVSSEVGMRLEDVRIEDLGRADTIVIEKDNTTVIVNGPARSSVKERCDKIRSEIQEATSDYDKEKLQERLAKLSGGVAVIRVGGATEVELKERKDRVEDAMHATKAAVEEGIIPGGGTAFLRCVKPLEEVIKSAKVQERGRDFICGIDAVRKALSSPCYQIASNAGKEGGVVVAEVLKASDVNVGYDARHDQYVDMIKSGIIDPTKVARTALQNAGSVAGLLNTTEVIIAQVPEKEKPNMGGGMGGGMGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFD6_BOVIN
Sequence: MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLEQQSEQQRETLAQLQQEFQRAQAAKAGAPGKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
What are the official names of this protein?
Prefoldin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: ATPD_BARQU
Sequence: MSDSFALIPLPLVDQRYAQALFDFVQEARSVENVEKAVASFLVVLDQHEDLKRFVQSPFFSIKEQIKVMRSVCENIKFADQGAGQILSNFLRVITVNRRLCALSGILQAFQHRVALSRREVSAQIISARPLSSHQEEELRVALEGVVRGKVLLHMCVDPTILGGLIIRLGSSQIDTSLVTKLSSLKLALKKEVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCT11_ORYSJ
Sequence: MGEGAAGSWYVTRDEVERGSPSRRDGVGAAKEAELRATYCSFIRDVGLRLQLPQVTIATATLLCHRFYLRQSHAKNEWQTVATVCVFLASKIEDTPCPLQRVIIVAYETMYRKDCNAAHRIYQKEVLEKQKELILVGETLLLSTIRFDFNIQHPYEPLKLALKKLGIFQMEVKQVAVNLINDAIRTTLVVQFKPHYIAAGSLYLAAKFNNFRLPSDGKVWWHEFDVAPKQLQAVIQQMTELFMGRNPCSMGPAIRPPPTPSLMERQQVIRPPPTPTLMERQPIIRPLPTPTLMENQHITHSLGAVMRHTHSSIRSLSNNFDREASRSLPLNIPANRKSTVCPARNEGNQSLRMHMGHSNGSDARFEKQYSRGALKADHVYHVVSGQKDLHVTGIRDLVRQKRTFHEVGEHPAPIDKSDTKSWIRKRHGRNVIVFDTKSSSWKKQKL
What are the official names of this protein?
Cyclin-T1-1, CycT1;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin T subfamily.
Protein: CURR_ASPTE
Sequence: MSLSHVAPSHDAYGQAKRRKVRKGTHSCWECKRRKMKCRFDPRIASACNGCRRRGSPCISQEFPEDLEEAVMNIGTTSSDGTPFDGRTRATTPSERTDQILTPVSTVREPSQYPRSPEQHLPTGNDTSQRKYERLSRFLHELLPSRADRESIFKASRHSSILSHELLTTPYITLHQNGLQTPESLLMTPQPNSHPVLIARYMLQFALFLQHLPPDLYKEIQGLSEPPRATMERLADAAIYHVTTNEALINSIESLECIMLESLYQVNLGNLRRSWVAGRRAMSLAQFMGFHRPDNQTRYYKALDPKTNYDPQIMWLRIIILDRQLCLLLGLPEGCTDHTMASSETRIANNCPMGRLEQLHCVAMSRILDRNASQPSGRDLTATRAIDLELQKAAGSLPSKWWLAPKLDSASTDLQAMFWDTRRLVLQICHYNLLNQLHLPYMLRPSTAGNKYEYSRITCVNASREVLSRYNSLRSFNRIAYSCRTVDFLALMAAMALLLAHMDSYRDGAENLLANQYLSDRGMIEQVQEHMSEINRLNSDELSAQSADLLKSLLAIDLEKGKGRVSVREAGSEGMLPQDGMGPEEESVVRVHIPYFGIIRIAREKQHATTASKPPVDRSPSSNSDAQLRFSTLTHPSNALPLSPNTTSNPLSFAVADAAAPHEFTTPFAHQQQQPCQPTFSNPGLSLTPSPLMQGGYPDLAAGSEDWAFQRVDMAFFESIMRNVGGDL
What is the function of this protein?
Transcription factor involved in regulation of the dehydrocurvularin biosynthesis gene cluster (PubMed:23335766).
What are the official names of this protein?
Dehydrocurvularin biosynthesis regulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_MYCPA
Sequence: MTVPATDSCPAPIRVPAGTTAAAAVRDAGLPGRGAPDAVVVVRDASGTLRDLSWVPDTDAEVVPVAANTDEGRSVIRHSAAHVLAQAVQELFPQAKLGIGPPITDGFYYDFDVPEPFTPEDLDKLEKRMRQIVKEGQLFSRRVYESKEQARAELAGEPYKLELVDDKSGDPDIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTRHIPAFKLTRSSAAYWRGDQNNASLQRIYGTAWESQEALDDHLRLIEEAQRRDHRKLGSELDLFSFPDEIGSGLAVFHPRGGVVRRELEEYSRRKHIEAGYEFVNTPHITKAQLFHTSGHLDWYADGMFPPMHLDAEYDDDGTVRKPGQDYYLKPMNCPMHTLIYRSRGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRARGFTMDDSHIFCTREQLHGELASLLRFVLELLGDYGLTDFYLELSTKDPDKFVGSDEVWEQATTSLADVAAESGLELVPDPGGAAFYGPKISVQARDALGRSWQMSTIQVDFNFPERFELEYTASDGTRQRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQAVGIPVADEHVPYLESVAAQLKSYGVRVEVDASDDRMAKKIVHHTAQKVPFMLLAGDRDVAAGAVSFRFGDRTQINGVPRDSAVDAIVKWIADRENSVPSAELVKVSSGE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_ECODH
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_STRAW
Sequence: MAARNTARKRAFQILFEGDQRGVDVLTVLADWIRHSRTDTRQPPVSEYTMQLVEGYAKKVNRIDELISQYAVGWTLDRMPVVDRNILRLGTYELLWVDETPDAVVLDEAVQLAKEFSTDDSPAFVNGLLGRLKELKPSLRREEA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: TRMD_STRA5
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKERGLLEINYHNFRENAEKSRHVDDEPYGGGQGMLLRAQPIFDTIDKIDAQKARVILLDPAGRTFDQDFAEELSKEDELIFICGHYEGYDERIKSLVTDEVSLGDFVLTGGELAAMTMVDATVRLIPEVIGKETSHQDDSFSSGLLEYPQYTRPYDYLGMTVPDVLMSGHHENIRKWRLEQSLRKTLERRPDLLENYAMTDEERLILEKIKTEIERTDTVNEQNNL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_ACIBC
Sequence: MRHYTGIDQLINSFDQALRSLVPGATAAQRQNPAETVEAKLGVEDARHVAGLMRVNHSGEVCAQALYHGQALTAKLPNVRREMQQAAIEEQDHLAWCEDRLKELNSHTSLLNPIWYGLSYGMGALAGIAGDKYSLGFVAETERQVSLHLQDHLNQLPAQDERSRKILEQMNEDELHHRHTALEAGGVELPYAVKITMTAISKLMTKTSYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNH2_CUTAK
Sequence: MGHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKREALFNVIMDKALAVSWVRVEADECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGLTVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIPGYDFAVHKGYATALHQRRLKELGPSRQHRMSYANVRRAARLHSS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_PROMP
Sequence: MSNNIYKIVSLYSFFSFQENSIIELKENLFSIEKNNDLSGLLIIAREGLNGTVCAEEGIIENILKLIKNIVGNNKLNIKVSYSKKKIFKKLKIKIKDEIVTMGVPEINPSEDSGTYIDSFSWNKLIKDKNTIVVDTRNHYEVSIGSFKKSINPNTENFSEFPEWVDDNLGKYIGDDDSKNIAMFCTGGIRCEKATSLLKKKGYKNIFHLQGGILKYLEDMSKEESLFEGECFVFDKRVALDHELKQGSYSICHACGMPISIEDQKNKEYREGIQCHFCVNKFSDNDRKRFEERQKQINKLKDKNQKVYKD
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: NLE1_CHATD
Sequence: MATLAPPPSKRQRREEIQRTQTQQDVTPLVATDLGSFKANFIDSDGNQMTDVVEINFADATEKNISNLLNTLLGRDREEFTPYRFRIHIPGKDLIIDQYPNDLLSLLQKHGVTNPFETTITLSAEPQAIFKVHAVSRLAHRIPGHGQPILSCQFSPVSSSRLATGSGDNTARIWDTDSGTPKFTLKGHTGWVLGVSWSPDGKYLATCSMDTTVRVWDPESGKQVNQEFRGHAKWVLALAWQPYHLWRDGTARLASASKDCTVRIWLVNTGRTEHVLSGHKGSVSCVKWGGTDLIYTGSHDRSVRVWDAVKGTLVHNFTAHGHWVNHIALSSDHVLRTAYHDHTKEVPGTEEERRAKAKERFEKAAKIKGKVAERLVSASDDFTMYLWDPTNNGSKPVARLLGHQNKVNHVQFSPDGTLIASAGWDNSTKLWNARDGKFIKNLRGHVAPVYQCAWSADSRLVVTGSKDCTLKVWNVRTGKLAMDLPGHEDEVYAVDWAADGELVASGGKDKAVRTWRN
What is the function of this protein?
Involved in ribosome biogenesis.  Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits.  Interacts with the AAA-ATPase Midasin, which is essential for the ATP-dependent dissociation of a group of nonribosomal factors from the pre-60S particle.
What are the official names of this protein?
Ribosome assembly protein 4, Notchless protein homolog 1, Ribosome biogenesis factor RSA4.
What is the protein family that this protein belongs to?
Belongs to the NLE1/RSA4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RLMN_CLONN
Sequence: MKNILNFTLDELKDWMDKNSESKFRAKQIFQWIYKKAVFNFDDMSNISKSTKEKLKENFYIQIPNVVKKYVSNIDGTEKFLFEYEDGNIIESVVMKYKHGNSICVSTQIGCRMGCKFCASTVDGVVRNLTSGEIIAQVLKAQKEICDRISNVVLMGSGEPLDNYDNVIKFLKLINDEDALNIGQRHITLSTCGIVPKIKELADQKMQITLAISLHAPNNEIRKSMMPIANKYTLEELLDACRYYYRTTNRRITFEYALVKGVNDSRENAEELIKISKGMLCHINLIPVNEIKENNYERSKSKDIEEFKETLIKHGIETTIRREMGSDINGACGQLRRNYIRNN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNC_YERE8
Sequence: MSESEKIKKVSIVIPVYNEQESLPILIERTSAACKLLTQPYEIILVDDGSSDNSAELLTAAANEPESHIIAVLLNRNYGQHSAIMAGFNQVSGDLIITLDADLQNPPEEIPRLVSVAEEGYDVVGTVRAHRQDSLFRKTASRMINMMIQRATGKSMGDYGCMLRAYRRHIVEAMLHCHERSTFIPILANTFARRTTEITVHHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSLVGSVIALSGFTLAVLLVVLRLVFGPEWAGGGVFTLFAVLFMFIGAQFVGMGLLGEYIGRIYNDVRARPRYFIQKVVGAEQTENNQEVEK
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSD_ALIB4
Sequence: MISTERLTHLKQLEAESIHIIREVVAEFSNPVMMYSVGKDSAVMLHLALKAFAPAKLPFPLLHVDTLWKFKEMIAFRDQRAKEEGFELLVHTNPEGVAMNISPFTHGSAVHTDIMKTQGLKQALNKYKFDAVFGGARRDEEKSRAKERIYSFRDKNHRWDPKNQRPELWNIYNGRVHKDESIRVFPISNWTELDIWQYIYLEQIPIVPLYFAAKRPVLEKDGVKIMVDDDRMPIGPDDVIKEEMVRFRTLGCYPLTGAVDSTATTLPEIIQEMLLTKTSERQGRVIDNDSAGSMEKKKIEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PANB_FRATH
Sequence: MKSVLGFKKAKVTQEKISMVTCYDYTLAKIINSTDIDCILVGDSGGMVLLGKKNTTYTTLDDMQFMTQAVANGATDKFIVADLPFMSYRQSLETTMQAVMALIQSGAHAIKLEGSSGNLDIIKHIVDSGVPIMGHIGMTPQFINSFGGFKVQGRTEEAAKHLLEEAKLLEQAGCFGIVLECIPANIAKDITQNLDIPTIGIGAGSNTDGQILVLQDMLGMNTDFQPKFVKKYIDGSKLFSDAINTYVKETKANTFPTKEHCYDYC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.