PharMolix/UniProtQA huggingface dataset:
Protein: RL16_CLOAB
Sequence: MLMPKRVKHRKVQRGRMKGKATRGNFIAYGDFAIQATECAWITSNQIEAARIAINRYVKRGGKLWIKIFPDKPVTQKPAETRMGSGKGSPEYWVAVVKPGRVLFEMSDVTEEQAREAFRLASHKLPIKTKFVTRKDFEEMGGEANEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NUOB_SALDC
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROA_CALS8
Sequence: MNVKIEGRRKIRAKVAIPSDKSISHRSIMIGSLARGTTEIENFLFAEDCLSTINCFKKLGAEIEIKNDKVIVKGKNYSLSVPQQVLDCGNSGTTTRLLLGILSTQEFEAVLDGDSSLRKRPMKRVTQPLSQMGASFEFLEKEDCLPIKVKGKKNLKPIDYTLPVSSAQVKSALIFAALKAEGKSVIKELPMSRDHTELMLKSAGADIATCFENGFYKIEVMPSNLEALKIKVPSDISSAAFFIVLALICEDSEVIIENCILNPTRTGIIDILKQMGADIEIGNVEIQNGELVGTIVARSSNLKGVVVDKNDIPRIIDEIPILAVAAAFADGKTIIDNASELRVKESDRIKTTLEMLRNFGAECYELENGLEIVGSRDNLKAGIVNSYNDHRIAMAASILACAVEGESTILNAECASISFPNFYEILLGHSKKV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_ACIBY
Sequence: MSNISLIVGLGNPGSEYAQTRHNAGFWFVEQLADKYGITLKNDPKFHGISGRGNIEGHDVRLLLPMTYMNRSGQSVVPFSKFYQIAPEAILIAHDELDMNPGVIRLKTGGGHGGHNGLRDIVPHIGPNFHRLRIGIGHPGSKERVSGHVLGKAPSSEQSLMDGAIDHALSKVKLLVQGQVPQAMNQINAYKPA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_CHLSC
Sequence: MTVPATSTRKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNAPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELLYDLFEAATGMRMMHNYFRIGGVAADLPHGWVDKCLDFCDYFLTGVAEYQKLITRNPIFLERVEGVGIIGGEEAINWGLSGPMLRASGIRWDLRKVDHYECYDEFDWEVQWQKEGDSLARYLVRISEMTESIKIIQQALEGIPGGPYENLEVRRFDRARDAEWNDFDYRFISKKPSPTFELSKQELYARVEAPKGELGIFLIGDNSVFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y746_STAAM
Sequence: MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIVSLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYGVTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPISLIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQSIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIHNYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDADDMVHVAKNQGRNKVMFNPIINL
What are the official names of this protein?
Uncharacterized membrane protein SAV0746.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_BIFLO
Sequence: MYAIVKAGGHQEKVEVGDVILVNRLDAKKGDTVEFPVSLVVDGDKVTLAAADLAKVSVKAEVVNDEAKGPKISIQKYKNKTGVARRKGHRQKLTIVKITAIA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: USTYA_ASPFN
Sequence: MAERSSNGYKEVPVRQSEESTIAEEEKDTLLEARSYSRRDRKRSRSKAVWFLIALLLLSNIGLLGGLIHYFRKTHHKEKDVPWLPPKTVGRGFVNINNDTALPDQPGLDQSLPHQRAMISVFHQLHCIYMTREGYYAAREGNLDQVNAAHLMHCWDYLRQAIMCHADTTLEWIPAPPNDKGSTGWGVEHTCGDFDAIARWAEDNRLKTTYGIH
What is the function of this protein?
Oxidase; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide (PubMed:24841822, PubMed:27166860, PubMed:26703898).  First, ustA is processed by the subtilisin-like endoprotease Kex2 that is outside the ustiloxin B gene cluster, at the C-terminal side of Arg-Lys, after transfer to Golgi apparatus through the endoplasmic reticulum (ER) (PubMed:24841822).  Cleavage by KEX2 generates 16 peptides YAIG-I to YAIG-XVI (PubMed:24841822).  To process the precursor peptide further, at least two peptidases are necessary to cleave the N-terminal and C-terminal sides of the Tyr-Ala-Ile-Gly core peptide which serves as backbone for the synthesis of ustiloxin B, through cyclization and modification of the tyrosine with a non-protein coding amino acid, norvaline (PubMed:24841822).  One of the two peptidases must be the serine peptidase ustP; and the other pepdidase is probably ustH (PubMed:24841822).  Macrocyclization of the core peptide derived from ustA requires the tyrosinase ustQ, as well as the homologous oxidases ustYa and ustYb, and leads to the production of the first cyclization product N-desmethylustiloxin F (PubMed:27166860, PubMed:26703898).  For the formation of N-desmethylustiloxin F, three oxidation steps are required, hydroxylation at the benzylic position, hydroxylation at either the aromatic ring of Tyr or beta-position of Ile, and oxidative cyclization (PubMed:27166860).  UstQ may catalyze the oxidation of a phenol moiety, whereas the ustYa and ustYb are most likely responsible for the remaining two-step oxidations (PubMed:27166860).  N-desmethylustiloxin F is then methylated by ustM to yield ustiloxin F which in turn substrate of the cytochrome P450 monooxygenase ustC which catalyzes the formation of S-deoxyustiloxin H (PubMed:27166860).  The flavoprotein monooxygenases ustF1 and ustF2 then participate in the modification of the side chain of S-deoxyustiloxin H, leading to the synthesis of an oxime intermediate, via ustiloxin H (PubMed:27166860).  Finally, carboxylative dehydration performed by the cysteine desulfurase-like protein ustD yields ustiloxin B (PubMed:27166860).
What are the official names of this protein?
Oxidase ustYa, Ustiloxin B biosynthesis protein Ya.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS2_LAWIP
Sequence: MAYVSMKQMLETGVHFGHQTRRWNPKMRPYIFGARNGIHIIDLQQTVKLYRAAHDKIVETVAAGGSVLFVGTKRQAQEAIATEATRAGQYYVANRWMGGTLTNFSTIQKSIERLNRLETMFSDGSVNRYQKKEILTLNREMDKLELTLGGIKNMERLPQLIFIIDPHRENIAVKEGRKLGIPIMAVTDTNCDPDLIDYIIPGNDDAIRAIKLFVTAMADACIEGEALQKDTKNKNLEEELKQIATAECNKESTSIEQELIIASEQTETKENNIEESVSEVVITNESELITE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MURB_BORBU
Sequence: MPKSLNNFLKKINIKPQTKNLANYTTYKIGNISKLFLTPKNIKEAENIFKAAIEEKIKLFILGGGSNILVNDEREIDFPIIYTGYLNKIEIHENKIVGECGADFESLCKIALDNSLSGLEFIYGLPGTLGGAVWMNARCFGNEISEILKKITFIDDKGKTICKEFKKEDFKYKISPFQNKNFFILKIELNLKKDNKKIIEEKMNKNKQARINRGHYLFPSGGSTFKNNKAFLKPSGQIIEECKLKGLSIGGATVSKYHGNFIININNATSKDIKSLIEKVKAEVYLKTGLLLEEEVLYIGFK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPL9_ORYSJ
Sequence: MDAPGGGGGGGGGGGGVDAGEPVWDWGNLLDFAVHDDDSLVLPWGDDSIGIEADPAEAALLPPAPSPQPAEAEAEAAGPASLPSSMQAEGSKRRVRKRDPRLVCPNYLAGRVPCACPEIDEMAAALEVEDVATELLAGARKKPKGAGRGSGAAVGGSGGGASRGTPAEMKCQVPGCEADIRELKGYHRRHRVCLRCAHAAAVMLDGVQKRYCQQCGKFHILLDFDEDKRSCRRKLERHNKRRRRKPDSKGILEKDIDDQLDFSADGSGDGELREENIDVTTSETLETVLSNKVLDRETPVGSDDVLSSPTCAQPSLQIDQSKSLVTFAASVEACLGTKQENTKLTNSPVHDTKSTYSSSCPTGRVSFKLYDWNPAEFPRRLRHQIFEWLSSMPVELEGYIRPGCTILTVFVAMPQHMWDKLSEDTGNLVKSLVNAPNSLLLGKGAFFIHVNNMIFQVLKDGATLTSTRLEVQSPRIHYVHPSWFEAGKPIDLILCGSSLDQPKFRSLVSFDGLYLKHDCRRILSHETFDCIGSGEHILDSQHEIFRINITTSKLDTHGPAFVEVENMFGLSNFVPILVGSKHLCSELEQIHDALCGSSDISSDPCELRGLRQTAMLGFLIDIGWLIRKPSIDEFQNLLSLANIQRWICMMKFLIQNDFINVLEIIVNSLDNIIGSELLSNLEKGRLENHVTEFLGYVSEARNIVDNRPKYDKQRQVDTRWAGDYAPNQPKLGISVPLAESTGTSGEHDLHSTNAASGEEENMPLVTKALPHRQCCHPETSARWLNAASIGAFPGGAMRMRLATTVVIGAVVCFAACVVLFHPHRVGVLAAPVKRYLSRNYSS
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANR52_HUMAN
Sequence: MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAVSPFSFSLLKNCSIAAAKTVGGCGALPHGASCPYSQERPGAIGLDGCYSE
What is the function of this protein?
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C, PP6-ARS-C, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C, Ankyrin repeat domain-containing protein 52.
Protein: LON_CAUVN
Sequence: MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).  CcrM is an important target of the Lon protease pathway in C. crescentus.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_LEUCK
Sequence: MKQTLFDKIWNTHVVAGEPGEAQLIYVDLHLIHEVTSPQPFDGLRSTKRQLRRPDLTFATMDHNVPTKDIFNIEDQMSRLQMDTLVKNAQEFGVPLASIGDDKQGIVHVVGPERGLTQPGKVIVCGDSHTATHGAFGAIAFGIGTSEVEHVMATQTIWQVKPKTMGIKVTGEMPKNTYAKDIIMAIIAEHGVSFGTGYAIEFYGETIEALSMAARMTLCNMSIEAGSKTGMVKPDQTTFDYIAGREFAPKKFDSAKAYWSQFYTDDETAFDEIITFDVSHLKPMVTWGTNPGMATAVDQILPEIRDDNDRAAYDYIGLEPGIPVTDIPLDYIFIGSCTNSRYEDLAIAAAMMKGQHLAPNITAWIVPGSRAIRNRAIATSIAKIFEAAGCEWREPGCSACLAMNPDKIPAGKHVASTSNRNFIGRQGAGSRTHLASPAMVAAAGIAGHFVDITEI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MEND_BACLD
Sequence: MTENPITKYIGNFIDELSLAGVTEAVICPGSRSTPLAILAASHPDINVHIHVDERSAAFFAMGMAKAMRKPVALICTSGTAAANFYPAVIEAHYSRIPLMILTADRPHELREVGAPQAIDQQFLFGNFVKFFTDSALPDSHPDMLAYIRSLAARAAGEAKKAPRGPVHINFPLREPLMPNLEDEPFQRLRSGSHVTVESGRFRADRHELVALSALIKETEKGVIVCGELQDDDAKEHIVALSQAAEYPILADPLSNLRNGTHSKETIIDAYDSLLKEEQLKRELMPELVIRFGAMPVSKPLFQLLKQNPSIRQIVVDPDGGWRDPTQLSAHMLHCTEEEIAVLADSAVNSENRTGNWLEKWRFANSRFRALLRNLEAEDLTFEGNIYRNLQHLIPDNSSVFVGNSMPIRDADTFFENQERTFRIFANRGANGIDGVVSTALGIYAATKEPVTLVIGDLSFYHDLNGLLVSKTLDIPLTVVLVNNDGGGIFSFLPQSAEERYFELLFGTPTGLEFEHAAKLYGGRYICPESSAHFADAYLSSVNRRGLDIIEVKTKRDDRVEQHRRMLDSALHEIRKEWPF
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: KINH_CAEEL
Sequence: MEPRTDGAECGVQVFCRIRPLNKTEEKNADRFLPKFPSEDSISLGGKVYVFDKVFKPNTTQEQVYKGAAYHIVQDVLSGYNGTVFAYGQTSSGKTHTMEGVIGDNGLSGIIPRIVADIFNHIYSMDENLQFHIKVSYYEIYNEKIRDLLDPEKVNLSIHEDKNRVPYVKGATERFVGGPDEVLQAIEDGKSNRMVAVTNMNEHSSRSHSVFLITVKQEHQTTKKQLTGKLYLVDLAGSEKVSKTGAQGTVLEEAKNINKSLTALGIVISALAEGTKSHVPYRDSKLTRILQESLGGNSRTTVIICASPSHFNEAETKSTLLFGARAKTIKNVVQINEELTAEEWKRRYEKEKEKNTRLAALLQAAALELSRWRAGESVSEVEWVNLSDSAQMAVSEVSGGSTPLMERSIAPAPPMLTSTTGPITDEEKKKYEEERVKLYQQLDEKDDEIQKVSQELEKLRQQVLLQEEALGTMRENEELIREENNRFQKEAEDKQQEGKEMMTALEEIAVNLDVRQAECEKLKRELEVVQEDNQSLEDRMNQATSLLNAHLDECGPKIRHFKEGIYNVIREFNIADIASQNDQLPDHDLLNHVRIGVSKLFSEYSAAKESSTAAEHDAEAKLAADVARVESGQDAGRMKQLLVKDQAAKEIKPLTDRVNMELTTLKNLKKEFMRVLVARCQANQDTEGEDSLSGPAQKQRIQFLENNLDKLTKVHKQLVRDNADLRVELPKMEARLRGREDRIKILETALRDSKQRSQAERKKYQQEVERIKEAVRQRNMRRMNAPQIVKPIRPGQVYTSPSAGMSQGAPNGSNA
What is the function of this protein?
Microtubule-dependent motor protein required for organelle transport (PubMed:22634595, PubMed:30254025).  Plays a role in endosome transport (PubMed:22634595).  Required for the transport of mitochondria along the axon of motor neurons (PubMed:30254025).  Involved in the nuclear migration of hyp7 hypodermal precursor cells (PubMed:19605495, PubMed:27697906).  Required for the formation of dendritic branches of PVD sensory neurons (PubMed:21205795).  In non-ciliated neurons such as the PVD and PHC neurons, required for the organization of minus-end out microtubules in dendrites (PubMed:30254025).  Also required for the minus-end out orientation of microtubules in dendrites of AQR gas-sensing neurons (PubMed:33460640).  Involved in the localization of unc-33 to neurites (PubMed:16236031).  Positively regulates cilium position and dendrite morphogenesis in the postembryonic AQR and PQR gas-sensing neurons (PubMed:33460640).  Plays a more prominent role in regulating dendrite morphogenesis in AQR than in PQR neurons (PubMed:33460640).  Plays a role in regulating the localization of grdn-1 to the distal dendrites of AQR sensory neurons (PubMed:33460640).
What are the official names of this protein?
Kinesin heavy chain, Uncoordinated protein 116, Protein unc-116.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm.
Protein: Y3031_ACIBS
Sequence: MIHHIPNVLSKEQVAEFRKLMEEANWVGGKVTAGTLSASVKRNQQLSEQDPLTHHLSDIVIKAIWQNPLFQAAALPHKIIPPLFNRYDEHESFGFHVDNSIRLIRGTAEQIRTDLSCTLFLSEPDEYEGGDLVIEDTYGYHEVKLPAGDVVLYPSTSLHEVSSITAGTRFASFFWVQSLVRDDSKRHLLFSLDESIRELRKSHGDSYSEVMKLTNIYHNLIRMWSEL
What are the official names of this protein?
PKHD-type hydroxylase ABSDF3031.
Protein: FTSZ_RICCN
Sequence: MVLNIKAPENIVLKPTITVFGVGGAGSNAVNNMISANLQGANFVVANTDAQSLEHSLCTNKIQLGVSTTRGLGAGASPEVGALAAQESESEIRNYLENSNMVFITAGMGGGTGTGSAPVIARIAKELGILTVGVVTKPFHFEGGHRMKTADKGLIELQQFVDTLIVIPNQNLFRIANEQTTFADAFKMADDVLHAGVRGVTDLMIMPGLINLDFADIKAVMSEMGKAMMGTGEASGEDRAIKAAESAISNPLLDHSSMCGARGVLINITGGSDMTLFEVDNAANRIREEVDNLDANIIFGSTFNPELKGMIRVSVVATGIDADKVPTYKPAIAETTNIVPEETYNKAIAQPTQIEEMPDFNSYSTENIEITDSPINQNFIGNEKELGLHANTFNKSEDDSPKPSFLGKIWGSLRASNNQTLERKNVVVSTLDQDNKESDIHDIPAFLRKKRD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: FOLD1_PSESM
Sequence: MTAKLIDGKAIAASLRQQIAKRVAERSQQGLRTPGLAVILVGSDPASQVYVSHKRKDCEEVGFISQAYDLPAETTQVALTNLIDRLNEDAAVDGILLQLPLPAHLDASLLLERIRPDKDVDGFHPYNVGRLAQRIPLLRPCTPKGIIALLESTGVDLYGLDAVVVGASNIVGRPMAMELLLAGCTVTVTHRFTKDLAGHVSRADLVVVAAGKPGLVKGEWIKPGAIVIDVGINRQDDGKLVGDVVYETALPRAGWITPVPGGVGPMTRACLLENTLYAAETLHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HIS7_FRACC
Sequence: MARTARIERKTLESDVLVELDLDGTGISSSDTGVPFFDHMLSQLGKHGGFDLTVRTRGDLHIDAHHTVEDTSIAFGSALREALGDKAGIRRFGDATVPLDEALAQAAVDLSGRPYCVHVEPDLVGMIGTYDTTLTRHIFESITASARLALHVRVLSGRNAHHVVEAQFKAVARALRDAVALDARVAGIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEM1_YEAST
Sequence: MSRRVVITGLGCVTPLGRSLSESWGNLLSSKNGLTPITSLPNYNEDYKLREKSIPSTITVGKIPENFQNENSAINKLLFTSQDERRTSSFIKLALRTTYEALHNAGLLNPNDITINTSLCNLDHFGCLIGSGIGSIQDIYQTSLQFHNDNKRINPYFVPKILTNMAAGNVSIKFNLRGLSHSVSTACATGNNSIGDAFNFIRLGMQDICVAGASETSLHPLSLAGFIRAKSITTNGISRPFDTQRSGFVLGEGCGMIVMESLEHAQKRNANIISELVGYGLSSDACHITSPPADGNGAKRAIEMALKMARLEPTDVDYVNAHATSTLLGDKAECLAVASALLPGRSKSKPLYISSNKGAIGHLLGAAGAVESIFTICSLKDDKMPHTLNLDNVLTLENNEADKLHFIRDKPIVGANPKYALCNSFGFGGVNTSLLFKKWEGS
What is the function of this protein?
Possibly involved in the synthesis of a specialized molecule, probably related to a fatty acid, which is essential for mitochondrial respiration.  Is essential for oxygen uptake and the presence of cytochromes A and B.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase homolog, Beta-ketoacyl-ACP synthase homolog.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DNAK_RICPU
Sequence: MGKVIGIDLGTTNSCVAVMEGKEPKVIENAEGERTTPSIIAFANGEKLVGQSAKRQAVTNHRNTIYAVKRLIGRNFIDPMVKKDQGIVPYNIVKADNGDAWVEADNNKYSPSQISAFILQKMKETAENYLGDKVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGFEKSASKTIAVYDLGGGTFDVSILEIADGVFEVKSTNGDTFLGGEDFDTRILNHLIDVFKKENGIDLSNDPLALQRLKEAAEKAKKELSSAVTTNINLPYITADSSGPKHLNIKFTRAELEKLVDDLIEKTIEPCRKALQDAGFKASDIQEVVLVGGMTRMPKVQEAVKKFFGREPHKGVNPDEVVALGAAIQGGVLNKEVTDILLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTADDNQHAVTIRVFQGEREMAKDNKLLGQFNLEGIPLAPRGLPQIEVTFDIDANGIVHVSAKDKASGKEQKVTIQASGGLSDAEIEQMVKDAEQNADEDKKRKELIEAKNAADSLVYSTEKTLTEYGDKLSSDDKGAVEEALAALKAVLESEDTALIKEKTESLTAASMKIGEAMYKAQSESQPAAESAANDEKIVDADFQDVEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PSD_COXB2
Sequence: MTKLHKYLPQRTLSKIVGWLATREWGLLTQWAIRLFIRHYGINMQEAQYPDIGHYPSFNAFFTRYLKRELRPVVEEPRAIASPVDGIISEMGQIKGENLIQAKNHHYTITALLGEDPSRASQFLDGDFFTAYLAPKNYHRIHMPLDGRLIEMIHIPGKLFSVNPASVQTVPRLFARNERAVCLFETENGLMAVILVGAMLVGSINTVWHGTVVPTAEGIAVHNYREKNIKFKRGEEIGHFKMGSTVILLFPKNTIQWNPNCQPKGTICYGENIGTVSLIEVA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.