PharMolix/UniProtQA huggingface dataset:
Protein: SYK_CHLCV
Sequence: MSEAEYLTQEDFLQRSNKLQEISDLGINPYPYEFPGTSSVEEIKQEYASQTLGNSEDATNKKTPKVKISGRMVLFRSMGKNAFAQILDNDQKIQVMFNRDFSSVAGLPEDAEISPIKFIEKKLDLGDILGIEGYLFFTHSGELTILVETVTLLCKALISLPDKHAGLSDKEIRYRKRWLDLISSDEVRQTFFKRSRIIKLIRQYMDAQGFMEVETPILQNIYGGAEATPFVTTLNALHSEVFLRISLEIALKKILVGGTSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAANVDYHSVMTYVENLVEYLVCALNDGSTVLTYSHLKQGPQTVDFKAPWIRMTMKDSIKTYGDVDVDLHADHELRNILKERTSLPEESYATAPRGLLITALFDELVCDKLIAPHHITDHPIETTPLCKSLRSGDADFVERFESFCLGKELCNAYSELNDPLHQRMLLEKQMEKKALDPDSEYHPIDEEFLEALCQGMPPAGGFGIGIDRLVMILTDAASIRDVLYFPAMRRLESENN
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_POPAL
Sequence: MFPMVTGFMNYGQQTIRAARYIGQSFMTTLSHVNRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWELETNIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYNRHELNYNQIALGRLPMSVIDDYTIRTILNSPQSLIKMGKPPLIKD
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HPRL2_HALWD
Sequence: MERLHESLHEAPIIDKDGYEYLVHPISNGVPVLEPGLLREVVIDIMQQSDFNVDKIVAPEAMGIHLATALSLQTDVPLVVIRKRSYGLPGEVALHKSTGYSESEMYINDIEAGDRILIIDDLLSTGGTLAAICGALDDIGTEIIDIVVVIRKIGQSAMDELEHDVTSLVDITVEDGEVTIQ
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: TAL_STRP8
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERS1_ORYSJ
Sequence: MDGCDCIEPLWPTDELLIKYQYISDFFIALAYFSIPLELIYFVKKSSFFPYRWVLIQFGAFIVLCGATHLINLWTFTTHTKTVAMVMTVAKVSTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAEQLDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGGTLGLEECALWMPSRSGSSLQLSHTLRHQITVGSTVSINLPVVNQVFSSNRAIIIPHTSPLARIRPLAGRYVPPEVAAVRVPLLHLSNFQINDWPELSAKSYAIMVLMLPSDSARKWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDLARREAEMAIRARNDFLAVMNHEMRTPMNAIIALSSLLLETELTPEQRLMVETVLKSSNLLATLINDVLDLSKLEDGSLELEIKAFNLHAVFKEVMSFIKPIAAIKRLSVSVMLAPDLPLCAIGDEKRLMQTILNISGNAVKFTKEGHITLVASVVKADSLREFRTPDFHPTASDDNFYLKVQIKDTGCGISPQDLPQVFTKFAQSQPGGNRGYSGSGLGLAICKRFVTLMGGHIWLDSEGTGRGCTVTFVIQLGICDNTNAYQQKLIPLVWPSSGDADFVGPVPNAPNEEKGQASLKSRYQRSI
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as a redundant negative regulator of ethylene signaling.
What are the official names of this protein?
Probable ethylene response sensor 1, OsERS1, Ethylene response factor 1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYDND_GLUOX
Sequence: MHPYRTHDCSALREENAGQVVRLSGWVHSKRDHGGLLFIDLRDHYGVTQIVIPAGTDLLEKAERLRVESVITVTGKVVVRHGSQRNPNLPTGDVEVLADALEVRSSAEVLPFQVAGNENYPEDLRLKYRYIDLRRDKMHQNIMLRSKVITSLRQRMIEQGFTEFQTPILTASSPEGARDFLVPARLHPGKFYALPQAPQQFKQLAMVAGFDRYFQIAPCFRDEASRADRSPGEFYQLDFEMSFVTQEDVFTVLEPVLAGVFNEFTPEGWKITDGAFPRIPYADAMRDYGSDKPDLRNPLIIKDVTDAFRDSGFGLFAKIAASGGQIRAIPAPGAGDRPRGFFDKLNSWARENGAGGLGYIIFGEEGGKGPIVKNLEADRVESIREICGLKAGDAVFFAAGKGDEVAKFSGVVRTKVATELDLIEKNAFRFCWVVDFPMYELNEETGKVDFSHNPFSMPQGGLEALNTQDPLTINAYQYDIVCNGVELSSGAIRNHLPDVMLRAFEIAGYGPEVVEERFGGMLNAFRYGAPPHGGAAPGVDRIVMLLADEPNIREVILFPLNQSGEDLMMEAPAPVEPARLKELHLALDLPKPKPTASK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_ESCF3
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIIAIAGQELNEKGFRSDDIQIRDADTLLEISENSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPPC_BACSU
Sequence: MNVQEQQAIRKLLSRIERQTKMKNADNISRTNAYKAFYDRHPEIKWSLLASFVSRNAGWSMTDLKGSLFQLGLRERQQKWFFLAYERANWLIFSDAYPQLLLYHWSKRVGKPLFHLLHVFGVSQFMSEEWTRFWHERNTERLMYALIINEQNTIQTPIIQNPSFKKNVFDTIPFYLSDWFHFNTVIFPSSNGFFYGISVKRFSKAEERIRLGKQLSQLLFKPELFSSFYHFLHTVPHTGSRFDMEKMIGITKRTSPMLRTCYPELIHSLDGTKTDWFHGKIKKTFFRREELPKQIELTDWYLHKKRQLHALFAVEQWLKK
What are the official names of this protein?
Uncharacterized protein YppC, ORFX.
Protein: Y4853_BACC2
Sequence: MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYDHVMKRETFSISEMQAITEELGTLIKK
What are the official names of this protein?
UPF0435 protein BCG9842_B4853.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: RS15_THEP1
Sequence: MVSLDPEKKNEIIKEFQIHENDTGSVEVQIALLTARIKHLTEHLRKHPKDFHSRRGLMKMIGRRRKMLKYLRHKKPEVYRELIAKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TPIS_RALSO
Sequence: MSARPKLVVGNWKLHGSLNGNAELLEKIKAAGQTRAALAVCAPFPYLAQCQSVLAGSSVAWGAQDVSAETRGAFTGEVAASMLSEFGCGYAIVGHSERRTYHGETDAQVAIKALRALEHGITPIVCVGETLAQREAGETELVVARQLEAVLESLSVEQLGHIVVAYEPVWAIGTGKTATSEQAQAVHAFLRGRVAACDAGVAQRMPILYGGSVKPDNAAELFTMADIDGGLIGGASLKAEDFLAIGRA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STIP_ACIAD
Sequence: MAIINKDKATELILKQGFSGSYQSEQVTFLLKRTHIEPTDTAEKERLIQSGEKHYSQMISLENAPTARHLELFEQAMQQGQQRLAQEVQQLAQTLVVEFNEPIVLVSFVRAGVPLGVLLYHAIQDLGRDCVHYGISIIRDRGIDFAALETIIARHGHASIVFVDGWTGKGAIRQELQRSLGNDTRFIGKPLPLVVLSDIAGCAWLAASGDDWLIPSGILGSTISGLISRSICEGETLSADEITAENIDQWHRCIEYHHLKEFDISQQFIQRINQIRLKLNPQSNAVWAETQQQAQQDQSQQVVHKLAQEYDIQNINRIKPSIAEATRAILRRVPDLVLLRDADDEDTRLLRHLTQITKTPVQVVGDQIAPYRAITLIQKLGKG
What is the function of this protein?
Cysteine protease that may play a role in regulating cell morphology in response to stressful conditions which likely cause oxidative damage.  Appears to catalyze its own cleavage, which probably leads to its activation.
What are the official names of this protein?
Cysteine protease StiP.
What is the protein family that this protein belongs to?
Belongs to the cysteine protease StiP family.
Protein: URE12_BRUA2
Sequence: MTQISRQQYADLYGPTIGDKIRLGDSDLYVEIEKDLRATYGDELQYGGGKTLRDGMGSENFLTQEAGCLDLVITNVTVIDAIQGVVKADVGIRNGRIVGLGKAGNPSTKDGVTRGLVTGASTDAISGEHLILTAGGMDTHVHYIAPQQVEAALSNGITTLWGGGIGPVDGTNGVTTTNGPWNLEMMLRSIEGLPINFGIQGKGNSTGIAPLIEQLEAGAAGFKVHEDYGATPATIRACLSVADEYDVSVAVHTDTLNESGYVEDTIAAFDGRSVHTYHSEGAGGGHAPDLLKVVGQNNILPSSTNPTLPCGKNSVAELFDMIMVCHNLNPKIPSDVAFAESRVRAETIVAESVLHDMGAISMIGSDSQAMGRLGETFLRAIQTADAMKKARGPLPEDAPGNDNFRVLRYIAKVTINPALTAGVGDVIGSIESGKFADLVLWEPAFFGVKPKLVLKGGLVAWANMGDPNASLPTPQPMYYRPMFAAYGSALQKTSITFVSRAAYDKGVADRFGLQRLVMPVSGTRVIGKAHMVRNSYLPNIEVDPQTFAVKVDGVHATVKPPQSISLNQLYFFS
What is the function of this protein?
Disrupting the ure2 operon has no effect on urease activity or pathogen survival in BALB/c mice when administered orally.
What are the official names of this protein?
Urease subunit alpha 2, Urea amidohydrolase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433F_HUMAN
Sequence: MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negatively regulates the kinase activity of PDPK1.
What are the official names of this protein?
14-3-3 protein eta, Protein AS1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: TGT_METPP
Sequence: MLRFDLLHTEGHARRGRLTLNHGVVETPIFMPVGTYGTVKGVMPASLEAMGAQIILGNTFHLWLRPGLDVLRQFGGLHRFENWQRPILTDSGGFQVWSLGAMRKISEEGVKFASPVNGDKLFLTPETSMQIQTVLNSDIVMQFDECTPYETSGHLTTEQEARASMELSLRWAARCKTEFARLENPNALFGIVQGGMFEPLRQASLDALVAMDFPGYAIGGVSVGEPKDEMLRIMAHTPHRLPAHKPRYLMGVGTPEDLVEGVTQGVDLFDCVMPTRNARNGHLFTRHGDLRLRNARYKTDERPIDESCTCTACNGFSRAYLHHLDRCGEMLGPMLTSIHNLHYFLNLMREVREALDAGRFEAFRAQFRADRARGV
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TARI_STRZJ
Sequence: MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPLTPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMIEKD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: TFPB_ACIAD
Sequence: MTYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTSKPFDILRLSQWLAEKVGLPLYVIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIGTDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYYQVSRAVHSSKNATAYERDNKGVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLHTIYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEKLVMRIFDPDVLVRSFEQLGFDEILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQLATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRALMRQDPDIIMVGEIRDQDTANMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCKVLSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVSSEANLNQLKSEAKKQGIQPLRIAGARKILEGVTSLEEVLRVVPLT
What is the function of this protein?
ATPase component of the type IV pilus (T4P) (By similarity).  Acts as a molecular motor to provide the energy that is required for biogenesis of the pilus and the extrusion of substrates generated in the cytoplasm (By similarity).  TfpB is required for optimal T4P extension and, consequently, efficient natural transformation.  May play a role in initiating T4P extension (PubMed:34145281).
What are the official names of this protein?
Type IV pilus assembly ATPase TfpB, Type four pilus PilB-like protein.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGP_EBOSU
Sequence: MGGLSLLQLPRDKFRKSSFFVWVIILFQKAFSMPLGVVTNSTLEVTEIDQLVCKDHLASTDQLKSVGLNLEGSGVSTDIPSATKRWGFRSGVPPKVVSYEAGEWAENCYNLEIKKPDGSECLPPPPDGVRGFPRCRYVHKAQGTGPCPGDYAFHKDGAFFLYDRLASTVIYRGVNFAEGVIAFLILAKPKETFLQSPPIREAVNYTENTSSYYATSYLEYEIENFGAQHSTTLFKIDNNTFVRLDRPHTPQFLFQLNDTIHLHQQLSNTTGRLIWTLDANINADIGEWAFWENKKNLSEQLRGEELSFEALSLNETEDDDAASSRITKGRISDRATRKYSDLVPKNSPGMVPLHIPEGETTLPSQNSTEGRRVGVNTQETITETAATIIGTNGNHMQISTIGIRPSSSQIPSSSPTTAPSPEAQTPTTHTSGPSVMATEEPTTPPGSSPGPTTEAPTLTTPENITTAVKTVLPQESTSNGLITSTVTGILGSLGLRKRSRRQTNTKATGKCNPNLHYWTAQEQHNAAGIAWIPYFGPGAEGIYTEGLMHNQNALVCGLRQLANETTQALQLFLRATTELRTYTILNRKAIDFLLRRWGGTCRILGPDCCIEPHDWTKNITDKINQIIHDFIDNPLPNQDNDDNWWTGWRQWIPAGIGITGIIIAIIALLCVCKLLC
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in GP2, releasing the fusion hydrophobic peptide.
What are the official names of this protein?
Envelope glycoprotein, GP1,2, GP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[GP2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site. SUBCELLULAR LOCATION: [GP1]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=GP1 is not anchored to the viral envelope, but forms a disulfid-linked complex with the extravirion surface GP2. In the cell, both GP1 and GP2 localize to the plasma membrane lipid rafts, which probably represent the assembly and budding site. GP1 can also be shed after proteolytic processing. SUBCELLULAR LOCATION: [Shed GP]: Secreted. Note=GP2-delta bound to GP1 (GP1,2- delta) is produced by proteolytic cleavage of GP1,2 by host ADAM17 and shed by the virus.
Protein: 3NO29_NAJSP
Sequence: MKTLLLTLVVVTIVCLDLGYTLTCLNCPEMFCGKFQTCRNGEKICFKMLQQRRPFSLRYIRGCAATCPGTKPRDMVECCNTDRCNR
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak neurotoxin 9, Wntx-9.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSRM_ASPN1
Sequence: MFLLHFPSALIILVPSHRIAFTMSTDHSARSPRLRACVRCQQRKVRCDHKSPCGNCVASDSQCVPATLTPRRRRFQERVLLDRLRHYEGLLRQHNIYFEPLHPQAKQEPVIADVPRDCERSETARAQTPVQSQAVDLWQAISRVTLEPEDDDGDSPDVQADGVENAWDHHVDQPEANDQTGDDLLFGQPQANVNVLALHPEQAQIFRLWQTYLENVNPLLKVTHTPTLQPRIVDAVSDLGDIHPTLEALMFSIYCIAVMSLADNECHRLLKSSKEDLLARYRLGCRQVLIKCRPWQFTNVDGLTAVYLYLVSVSPQTDPRSLSSMLAAALRIAQRMGLHNESTYTRYTAVEAEMRRRLWWSLVIFDHRMCEMSDYKVTTLTPTWDCRIPLNKPTEALFAVVRSELADLIRHTTFHINFVNPVLAAVAKAKDPGHVSISADGEMLTIQRAIEEKYLAFCDPADPLHFMTIWTTRGYLARNRLLEHYARHLSSPAMQQTDAQRNAALSYALEMLECDTRLRVSPLTCRYRWLVDFHVPALAYIHVLNDLRKRPTESHAGKAWQAMSENYEARAMHPKPSGQGVFTVFARVVLQAWGAREIFLRQRGMPVEAPQIVLDIRSKVGQTSSGSSMVPSCSTGEPSHSSIAISAHSEAIPAQMNFTGHSADGQAFPGPDLGPSSFPDVAGPPGMDIDIDQFWTAMDWRLMHTQAW
What is the function of this protein?
Transcriptional regulator; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer neosartorin, which exhibits antibacterial activity.
What are the official names of this protein?
Transcriptional regulator nsrM, Neosartorin biosynthesis cluster protein M.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPF_PSECP
Sequence: MIIPRTGIGVDVHAFAAEGEARQLWVGGLLWPGERGLAGHSDGDPVAHAAADALFSAAGIGDLGTHFGTDRPEFAGASGVTLLAEAARIVRAAGFEIGNIAVQFVANRPKFGPRREESQQVLSDAAGAPVSVTATTSDGLGFTGRGEGISAVATALVYPRLSESIG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CABL2_HUMAN
Sequence: MAAAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQVPTGLGLDGQRQRKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTHKSDSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGDTLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLSKIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF
What is the function of this protein?
Unknown.  Probably involved in G1-S cell cycle transition.
What are the official names of this protein?
CDK5 and ABL1 enzyme substrate 2, Interactor with CDK3 2, Ik3-2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
Protein: EFP_SHEB9
Sequence: MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKLEDIILDRLDCTYSYFADPMFVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTVTVADFVKVGDKIEIDTRTGEFKKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_VIBCH
Sequence: MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTGLYHCTCCQSALFSSENKYDSGCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHLGHVFEDGPKTTGLRFCVNSVSLIFNKK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: PROFP_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEDHRLTAAAIVGHDGSVWAQSATFPQFKPVEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-4, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LUMI_ARATH
Sequence: MDAFKEEIEIGSSVESLMELLDSQKVLFHSQIDQLQDVVVAQCKLTGVNPLAQEMAAGALSIKIGKRPRDLLNPKAVKYLQAVFAIKDAISKRESREISALFGITVAQVREFFVTQKTRVRKQVRLSREKVVMSNTHALQDDGVPENNNATNHVEPVPLNSIHPEACSISWGEGETVALIPPEDIPPDISDSDKYFVENIFSLLRKEETFSGQVKLMEWIMQIQDASVLIWFLSKGGVLILTTWLSQAASEEQTSVLLLILKVLCHLPLHKASPENMSAILQSVNGLRFYRISDISNRAKGLLSRWTKLFAKIQAMKKQNRNSSQIDSQSQLLLKQSIAEIMGDSSNPEDILSLSNGKSENVRRIESSQGPKLLLTSADDSTKKHMLGSNPSYNKERRKVQMVEQPGQKAAGKSPQTVRIGTSGRSRPMSADDIQKAKMRALYMQSKNSKKDPLPSAIGDSKIVAPEKPLALHSAKDSPPIQNNEAKTEDTPVLSTVQPVNGFSTIQPVNGPSAVQPVNGPLAVQPVNGPSALQPVNGPSAVIVPVQADEIKKPSTPPKSISSKVGVMMKMSSQTILKNCKRKQIDWHVPPGMELDELWRVAAGGNSKEADVQRNRNRRERETTYQSLQTIPLNPKEPWDREMDYDDSLTPEIPSQQPPEESLTEPQDSLDERRIAAGAATTSSSLSSPEPDLELLAALLKNPDLVYALTSGKPSNLAGQDMVKLLDVIKTGAPNSSSSSNKQVEERVEVSLPSPTPSTNPGMSGWGQEGIRNPFSRQNQVGTAVARSGTQLRVGSMQWHQTNEQSIPRHAPSAYSNSITLAHTEREQQQYMQPKLHHNLHFQQQQQQPISTTSYAVREPVGQMGTGTSSSWRSQQSQNSYYSHQENEIASASQVTSYQGNSQYMSSNPGYESWSPDNSPSRNQLNMRGQQQQASRKHDSSTHPYWNQNKRWR
What is the function of this protein?
Seems to play a role in the regulation of flowering time in the autonomous flowering pathway by repressing FLOWERING LOCUS C expression.
What are the official names of this protein?
Homeobox protein LUMINIDEPENDENS.
What are the subcellular locations of this protein?
Nucleus.