PharMolix/UniProtQA huggingface dataset:
Protein: MDH_DELAS
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDCAFPLLAGIEAHSDPLQAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQLAAKAGFKVGDIRKLTVWGNHSPTMYADYRFATVNGESVKAKINDQAWNKDVFLPTVGKRGAAIIAARGLSSAASAANAAIDHMRDWALGSGGEWVTMGVPSNGEYGIPAGIVFGFPVTTENGEYKIVEGLEIDAFSQECIDKTLAELQGEQDGVKHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: PDXJ_RHOPB
Sequence: MSKALPLRLGVNVDHVATLRNARGGKHPDPVRAALAAIEAGADGITAHLREDRRHIRDADMARLKAEISKPLNFEMAATPDMVQIALATKPHAVCLVPERREEVTTEGGLDVIGHHNTLAPFIARFNDAGIRTSLFIAADPAQIEMAAELHAPVIEIHTGAWCDAVEAGNAVKAEAEWQRIVAGAKLAQSVGLEVHGGHGLDYATAQTISALPQIAELNIGFHLMGEALFVGLTESIRRMRAAMARGRQALEATA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PYRHO
Sequence: MDPYKVIIRPVVTEKAISLIEKENKLTFIVDRRATKTDIKKAIEEIFNVKVEKVNTLITPKGEKKAYVKLKPEYSASEIAARLGLF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MURD_HALH5
Sequence: MKHTEQFHQKHILVLGLAKSGEAAARLLHDLGAIVTVNDQKPLADNPQAQKLQKEGIHVVCGEHPISLLDGKELVVKNPGIRYDNPIVEEAIKRGISVVTEVELASKVSEAEIVAITGSNGKTTTTSLVVEMLKGSAREPKVAGNIGVVASDVAREATADDVIVMEVSSFQLMGTSHFRPKVAILLNIFDAHLDYHGSKENYVAAKKKIVENMKEEDYFVYNADDPLVSKVAAETKATPIPFSRSTVVKSGAYVDGETYMFRGEKIVEKGDVVLPGDHNVDNVLAAMSAALLMGATKEQIHHVLSTFSGVEHRLQFVGTAFERKWYNDSKATNILSTTAAIQSFTDPIVLLAGGLDRGNSFDDLIPALQKVKAVVLFGETKHKLAQAAMEAGVETIVEAERVEDAVRKALDVSANGDVILLSPACASWDQYRTFEERGEAFVTSIEGLQE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
Protein: PLY7_ARATH
Sequence: METARLFKLVCVICIASLIPTIRANVADETDEYWVNKANEARKHTLMAYHPDPYEIVDHFHERHYDNSTDVEGTEEEKAVASEEEDVIEMISSPTNSTRRSLTGRGKGKGKGKWSKLTGPCTASNPIDKCWRCQPDWARRRKKLVHCVRGFGYRTTGGKRGRIYVVTSPRDDDMVNPRPGTLRHAVIQKEPLWIVFKHDMSIRLSQELMITSDKTIDARGANVHIAYGAGITMQYVHNIIIHGLHVHHIVKSSGGLIRDSINHFGHRGEADGDGISIFGATNIWLDHISMSKCQDGLIDAIMGSTAITISNSHFTHHNDVMLLGAQNNNMDDKKMQVTVAYNHFGKGLVQRMPRVRWGFVHVVNNDYTHWELYAIGGSQGPTILSHGNRFIAPPHKQHYREVTKRDYASESEWKNWNWRSEKDVFMNNAYFRQSGNPHFKCSHSRQQMIKPKNGMAVSKLTKYAGALDCRVGKAC
What are the official names of this protein?
Probable pectate lyase 7.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: LDHA_PIG
Sequence: MATLKDQLIHNLLKEEHVPHNKITVVGVGAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSRLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWILGEHGDSSVPVWSGVNVAGVSLKNLHPELGTDADKEHWKAVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKEDVFLSVPCILGQNGISDVVKVTLTPEEEAHLKKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A, LDH muscle subunit, LDH-M.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37_RAT
Sequence: MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L37.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_SHEB9
Sequence: MNVSQDTIYAQASEHISDFQFDNRVAGVFSDMIRRSVPGYTQIINTIGDFADRFVMPNTQIYDLGCSLGAATLSIRRQIQGRQCRIIAVDNSESMVARCQENLNAYVSDTDVDLVCGDIRDIDIQNASLVVLNFTLQFLPPEDRETLIAKIYQGLNPGGILVLSEKIRFEDAPIQTLLEEQHLDFKRANGYSELEISQKRSALENVMKPDTLTTHQQRLTSQGFSHFSLWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: IHFB_PSEPU
Sequence: MTKSELIERIVTHQGLLSSKDVELAIKTMLEQMSQCLATGDRIEIRGFGSFSLHYRAPRVGRNPKTGQSVSLEGKFVPHFKPGKELRDRVNEDEHEEAHT
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: JZT74_CHIGU
Sequence: MKLAVVFLLTTVVFTLAQSQCENCADLQCNSTVHCCLVSTVRLPRWKREISRCGRLAIRRWRCEEPNSNGIYNRNCPCVPGLECREFRRGRRICLPEQSSTSTSSTQGPITSSTVTTQSEATTETETTTAAEGK
What are the official names of this protein?
U34-theraphotoxin-Cg1a, U34-TRTX-Cg1a, Jingzhaotoxin-74, JZTX-74.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXA_RHILW
Sequence: MSTIAESARIHPMAVVEDGAVIGEGVKIGPFCHVGPHVVLHENVELLSHAVVAGRTVIGKGTRIFPMAVIGGDPQSVHHGGEETTLSVGANCTMREGVTMNTGTADFGGQTIVGDNNLFLANSHVAHDCKVGNHVIMSNNVMLAGHVVIEDRVILGGGSAVHQFTRVGRQAFVGGLSAVSYDVIPYGMLNGNPGLLSGLNVVGMTRAGVDRAVIHRVRRAYKSIFEGTGSVRENAAAIRDEYADCEQAVQILDFIAADSDRALSSPTRGQKG
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_KOSOT
Sequence: MRFIWLAIIGYLFGSIPWGYIIPKLRGIDIRKVGSGNVGGTNVLRNLGGFWGAITMVLDGFKPFIPIMIAKHTFGVSVSDAMMIGFFAGVGHCYPIWLKFKGGKSVAVSVGTISGTKASLVPVFFAVWLPIVLITQYVSLGSILSLAVITILYFLTDSWQTGIWMLALFLLTTYRHRGNIVRLIRGEERKTDLIAAFTKRNKNKKEG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_MYCPA
Sequence: MGDASLSVLASSQVVAEGGNNFLVPNGTFFFVLAIFLIVLAVIGTFVVPPVMKVLRERDAMVAKTAADNRKAAEQFEAAQADYEEAMTEARVQASSLRDNARAEGRKVVEDARAKAEQEVLSTLQLAARQLKRERDAVELDLRANVASMSATLASRILGVDVAPAAATTSATKTSGR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AROQ_YERPS
Sequence: MSDKFHILLLNGPNLNLLGTREPEKYGYTTLAEIVSQLEIQAQGMDVALSHLQSNAEHALIDSIHQARGNTDFILINPAAFTHTSVALRDALLGVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGADGYNFALQAAVNRLSKSN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: TIG_STRA3
Sequence: MSTSFENKATNRGIITFTISQDEIKPALDQAFNKVKKDLNVPGFRKGHMPRTVFNQKFGEEALYENALNLVLPKAYEAAVAELGLDVVAQPKIDVVSMEKGQDWKLTAEVVTKPEVKLGDYKDLSVEVDASKEVSAEEVDAKVERERNNLAELTVKDGEAAQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGSKAGQTVDVNVTFPEDYQAEDLAGKDAKFVTTIHEVKTKEVPALDDELAKDIDDEVETLDELKAKYRKELESAKEIAFDDAVEGAAIELAVANAEIVELPEEMVHDEVHRAMNEFMGNMQRQGISPEMYFQLTGTTEEDLHKQYQADADKRVKTNLVIEAIAAAEGFEATDEEIEKEITDLASEYNMEADQVRGLLSADMLKHDIAMKKAVDVITSSATVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FTSY_MYCTO
Sequence: MWEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVDRSGGYTASSGITFSQTPTTQPAERIDTSGLPAVGDDATVPRDAPKRTIADVHLPEFEPEPQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDVEDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDLAPFEPAAFVDALLG
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: TRAP_SLCV
Sequence: MPNSSSSKVPSIKAQHRIAKKRAVRRRRIDLDCGCSIYIHINCAKDGNGFTHMGRHHCASGREFRFYLGGSKSPLFQDVQXGGSTLHAHKDIPHTNPVQPQPEESTKSSQSVPELPSLDGIDSSFWDDIFE
What is the function of this protein?
Strong activator of the late viral genes promoters.  Enhances the expression of the capsid protein and nuclear shuttle protein.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway.  Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense.  Determines pathogenicity (By similarity).
What are the official names of this protein?
Transcriptional activator protein, TrAP, Protein AC2, Protein AL2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae transcriptional activator protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=The phosphorylated form appears to accumulate almost exclusively in the nucleus, whereas the non-phosphorylated form is found in both nucleus and cytoplasm.
Protein: RUVC_SYNS9
Sequence: MRILGIDPGLARVGYGVIDTSGGQQRMLDCGIIRTEPGYSEGDRMVVIASDLRQLIRAWRPELAAVEKFFFYRSSTTISVVQARGVVMMTLARFKVPVVEFPPMQIKLALAGFGHAEKDEVLEAVMRELNLTDPPRPDDAADALAVALTGWFQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PROA_BACC2
Sequence: MNEVLAKGIKAKEVARELVLKTTDQKNEALAAIANQLIVETAYILEENKRDIEEGKEKGFSDSLLDRLLLNEQRIVDMTEGIKQLIELRDPIGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVSVIHRALKQTSLPSESVQLIEDTTRDSAKQLFTLNEYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHIFIDETADKQMAFNIIINAKTQRPSVCNAIETIVLHENWAEQYGSELFSSLKERGVELRGDNKAVAIDTSILLATEEDWETEFLSLTLAVKVVATVEEAIHHINTYGSMHSEAIITENEENVSKFFTSVDAAALYHNASTRFTDGSEFGFGAEIGISTQKLHVRGPMGLPALTSTKYVIRGNGQIRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN23_ORYSJ
Sequence: MALLSAPVRRRRSRVRVLLVCCCLLLALAAPSAAAAAAGHDYGDALAKSILFFEGQRSGRLPAAGQRAAWRGDSAVSDGGAAGVDLEGGYYDAGDNVKFGFPMAFTATMLAWGVVEFGDAMPPAERAHAADAVRWATDYLLKTISHPGVIFIQVGDPTKDHGCWERPEDMDTARTVYNISAARPGSDVAGETAAALAAASMVFRDDDPAYAARLLAGARSAFEFADEHKGAYSDDPELRAGGCPFYCDFDGYQDELLWGAAWLRRASKEGTYLDYIQNNGKTLGAEDSTNEFGWDNKHAGINVLVSKEFIDGEVLSLQSYKEFADGFICTLIPESSSPHITYTPGGMIYKPGGSNMQHVTSISFLLLTYAKYLSNSSRTVNCGNVSVGPATLQQLARKQADYILGDNPMKMSYMVGYGDRYPQRIHHRGSSLPSIKSHPQRIACNDGTPYYNSSSPNPNPLIGAVVGGPGEDDVYEDDRADFRKSEPTTYINAPLVGVLAYLVGNPDPGQGHVRH
What are the official names of this protein?
Endoglucanase 23, Endo-1,4-beta glucanase 23, OsGLU12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS8_ACISJ
Sequence: MTTPSAELPALARIRDDVRAMQAYVVADATGYLKMDAMENPFGLPPALQAALGQRLGQLALNRYPGTRQNDLKAALAAYAGAPAGSAVLLGNGSDELISLVALACARAQATVLAPVPGFVMYAMSAQLQGLGFVGVPLTADFELDEAAMLAAIAQHRPAITFLAYPNNPTATLWDEAVVQRIIDAAGAQGGIVVMDEAYQPFASRSWIERMRAQPERNGHVLLMRTLSKFGLAGVRLGYMIGPAALVAEVDKVRPPYNVSVLNTEAALFALEHADVFAAQADELRAARTELLAALRAMPGIERVWDSQANMVLVRVPDAARAYEGMKARKVLVKNVSTMHPLLAGCLRLTVGSSADNAQMLTALQASL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SYP_BORPE
Sequence: MRASKYHLNTLKEAPAEAEIASHQLMTRAGMIRKLAGGIYTYMPLGLKVIRKIEGIVREEMNAAGAIELLMPVVQPAELWMESGRWEQYGAELLRIKDRHQRDFVLQPTSEEVITDIARNEIQSYRQLPLNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDEAGAQRSYDIMYAAYQRIFQRLGLEFRAVAADTGSIGGSRSHEFQVIADTGEDLIVYNPESDYAANIELAEAPALLATRAAPGQDLEAVPTPGAAKCEDVAKLLDLPLARTIKSIVLAVDQPEGPAQVWLLLLRGDHELNEIKAGKLPGLAGFRFATETEILDHFGCKPGYLGPIKTARPVHVVADRTVANMADFVCGANREDYHYQGANWGRDLPEPELVADLRNVVEGDPSPDGKGALSIQRGIEVGHVFFLGTKYSEALKATFLDDNGKPAVLQMGCYGIGVTRIVGAAIEQNHDARGIIWPRAIAPYEVVICPVGWGKSETVRDTALALYEALRARGVDVMLDDRDSRPGVMFAEWELIGVPLRVTVGERGLNEGVVELQARREAEAAKVPVDQALAQTLAKLDLL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCB_ACIB3
Sequence: MNHFELFNLPVALDIDLASLKSNFLSLQQQYHPDKAADKDQALIKSSEINQAFKTLSQVDSRAAYLLALKKQDHHLDQSISDFEFLQSALELREQLDEATSSEHLRTLRLEVQQWIDGLVREFKIDYSEEDWAEARDTVRKLRFFQRVLNDIDKAEDQLLDDEDSFDLDDDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: ILVC_CORJK
Sequence: MAIDVFYDDDADLSIIQGRKVAIIGYGSQGHAHAQNLRESGVEVVIGLREGSKSRAKAEEAGFTVKTNAEAAEWADVIMLLAPDTSQAKIFAEDIEPNLNDGDALFFGHGLNIHFKLIEPADNIIIGMVAPKGPGHLVRRQFVDGKGVPCLIAVEQDPKNNGRDLALSYAAAIGGARAGVIPTTFEAETVTDLFGEQAVLCGGTEELIKTGFEVLVEAGYEPEMAYFECLHEMKLIVDLMFEGGIANMNYSVSDTAEFGGYLSGPRVIDADTKKRMKDILTDIQDGTFTKRLVANVEGGNKELEELRASYNDHQIEKTGAKLRDLMSWVKVDARAETA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CCL2_PIG
Sequence: MKVSAALLCLLLTAATFCTQVLAQPDAINSPVTCCYTLTSKKISMQRLMSYRRVTSSKCPKEAVIFKTIAGKEICAEPKQKWVQDSISHLDKKNQTPKP
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_PLAF7
Sequence: MAHVITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGVQKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAVCRAGAAANKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAPSFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGYEGKVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVSIEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALLLKVNQIGSITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQLLRIEESLGNNAVFAGEKFRLQLN
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (PubMed:19268421, PubMed:25787157).  In addition to glycolysis, involved in various processes such as parasite development and invasion (By similarity).  Plays an essential role during ookinete invasion of the mosquito vector midgut by mediating the interaction of the ookinete with the midgut epithelium and, further, by binding to mammalian host plasminogen in the blood meal, whose conversion to active plasmin promotes the invasion process (By similarity).
What are the official names of this protein?
Enolase, Pfen, Pfeno, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell surface. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Vacuole. Note=Partially localizes to the nucleus in rings and trophozoites (PubMed:19642995). Localization to the nucleus and food vacuole is higher in early and mid-stage trophozoites compared to the late-stage trophozoites and schizonts (PubMed:19642995). In the nucleus, localizes to heterochromatin region (PubMed:19642995). In rings, nuclear localization is dependent on the actin cytoskeleton (PubMed:19642995). In the trophozoite food vacuole, colocalizes with hemozoin, a product of heme detoxification (PubMed:19642995). Localizes to the cell surface of merozoites (PubMed:19642995). In gametocytes, predominantly localizes to the actin cytoskeleton (By similarity). In sporozoites, localizes to punctate structures beneath the cell membrane (By similarity). Localizes to the cell surface of ookinetes, especially on the apical pellicle complex that is involved in invasion (By similarity). When phosphorylated at Thr-339, localizes to the cytoskeleton (By similarity). When phosphorylated at Ser-42, localizes to the cytoplasm (PubMed:24009698). When ubiquitinated at Lys-138, acetylated at Lys-133 and Lys-375 and phosphorylated at Tyr-139, localizes to the food vacuole (By similarity). When triubiquitinated at Lys-138, appears to colocalize with hemozoin in the food vacuole (By similarity).
Protein: Y037_CHLPD
Sequence: MSSDPHMLGIQGEQIAAAYLSRHGYRIIQRNYRYRRNEIDIIAKKHATICFIEVKTRASLEKGHPSEAVTPKKQKEIIKAAKSYLFSLGTDRCECRFDVIAILVRSMKQEEIGLYDLDHFTDAFQAE
What are the official names of this protein?
UPF0102 protein Cpha266_0037.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.