PharMolix/UniProtQA huggingface dataset:
Protein: YCU3_CAEEL
Sequence: MALTCTDIPKFICAVLLPPIGVFLEKGCDYHLAICILLTILGYIPGIIYACYVILAY
What are the official names of this protein?
UPF0057 membrane protein T23F2.3.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MOAC_CHLAA
Sequence: MSEAHNELTHLDAAGHARMVDVGDKAVTAREAVARGRVVMQPETLALIMDGKLPKGDVLAVARVAGIMAAKRTAELIPLCHLLNLSHASVQFTPDPASNALEIEATVRCQGQTGVEMEALTAVSIAALTIYDMCKAVDKTMQIDQIRLIAKRGGRSGDWQRPR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ATP6_AGRFC
Sequence: MANDPTHQFLVQPIIPIEIGGVDFSFTNASLFMVATVAAASGFLYFATSNRGLIPTRMQSVAEMSYEFIASMLREGAGKKGMVFFPFVFSLFMFVLTANLLGMFPYFFTVTSQIIVTFALACLVIGTVIVYGFYKHGLHFFGIFAPSGVPKALLPLVASIEMISFLSRPISLSVRLFANMLAGHITLKVFAGFVASMGALGALGVGGAVLPLIMTVAMTALEFLVAFLQAYVFAVLTCMYLNDAVHGGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPIN1_MOUSE
Sequence: MKTPFGKTPGQRSRADAGHAGVSANMMKKRTSHKKHRTSVGPSKPVSQPRRNIVGCRIQHGWREGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS
What is the function of this protein?
Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2.  In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (By similarity).  Overexpression induces metaphase arrest and chromosomal instability (PubMed:18543248).  Localizes to active rDNA loci and promotes the expression of rRNA genes.  May play a role in cell-cycle regulation during the transition from gamete to embryo.  Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption (PubMed:23894536).
What are the official names of this protein?
Spindlin-1, 30000 Mr metaphase complex, SSEC P, Spindlin1.
What is the protein family that this protein belongs to?
Belongs to the SPIN/STSY family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Nucleus, nucleolus. Note=Associates with the meiotic spindle.
Protein: IHFB_BRUA4
Sequence: MIKSELVQIIASRNPHLFQRDVENIVGAVFDEITNALAEGNRVELRGFGAFSVKNRPARSGRNPRTGETVDVEEKWVPFFKTGKELRDRLNGAV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PSBH_ZYGCR
Sequence: MATQTIKQTSTSKGRQTSVGDILKPLNSEYGKVAPGWGTTVLMAVFMALFAVFLVIILELYNASVLLDGLAVSWQ
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1921_STAS1
Sequence: MKHYLITGGTGMIGSQLVKAIIQSDAHITILTRQDMTSSHPKISYVNWSQPNWENEIPDIDIVINLAGASLNKRWTKSYKQTIMLSRIQATQALFELFQNRKHKPEVLFNASAVGYYKPDLYRTYTELYKTLPFDFLSEVVYQWERMARQFETLGTRVVIGRFGMVLSNDGGALPMMKLPYDFYLGGKLGSGRQWYSWIHIDDLVRALLHTINTESARGVFNFTAPIVEHQNMFGYTLARVSHRPHHTWVPSLAIRLALGQMSTVVLDTQKVIPNKLQATHFKFKYPDLKIALEDLVH
What are the official names of this protein?
Epimerase family protein SSP1921.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: C553_PARDE
Sequence: MTSKTTASLLAICVACAASAIAGTALCADRRNAPAQAGAGAAAAVSGDAHEQPAAEAPAEEEEETPAVAATDGKLVLPNGQDITPDHMENGRWYTAEDIPTYKIAEEGAVDWATFSGYRRYSAECHVCHGPDGEGSTYAPALRKSVLTMGYYDFLEIAASGKQEVNTAANLVMPAFGTNKNVWCYIDDIYAYLLARGTGDLPRGRPAKREDKSDEFVAQEDSCMSG
What are the official names of this protein?
Cytochrome c-553I, Cytochrome c553I.
What are the subcellular locations of this protein?
Periplasm.
Protein: GPMA_AZOSB
Sequence: MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKRANKTLNIVLEELDALWLPVEHSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIPPPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVVPYWETVIVPQILSGRRILIAAHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAAVAGQGKAKG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ARMP3_ARMGA
Sequence: MTRILSEEVSPIWILTAIVVVAYTTVRYLRSPWRNLPPGPRGLPLIGNLLELRGKQWLTFTELGKKYGDLMYFNVAGQPLVVLNSQKVAADLLDRRAGKYSDRPRNIVASDIMTGGNLVVFTRYGDVWRRMRKAAHEGLNKGVVYKYHPIQTAEAVLLTAGVLAEPEKWNSHIRRTAASAIMSMVYDTPPTSEQDPSVKNINDFVARLTRAAMPGAHFVEFFPWMRYIPSKYAKWKREAEESYTKDSAMFEGLFNGVKDRVAKGDERPSLASTLIQDAGRHDLTDRENSWLAGTMYAAGAETTSGVMSWWTLAMIVYPETQKRAQAELDAVVGRDRLPSFADYEHLPYIRAMVKEALRWRMVDPVGLPHTSTEDDVYDGYFIPAGTILIANVWHLNRDPEIYGPDAEHFNPARHLDKDGKLAPGPADTKEESHVTYGFGRRICVGRHVANNSLFIDIAMMLWAMNIERATDENGVPLPLDVDGCIEDGLVTRPVPFKAKITPRFQEAQAIVEQERELLGYH
What is the function of this protein?
Cytochrome P450 monooxygenase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable).  The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene (PubMed:21148562).  The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity).  ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity).  The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity).  The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity).  The role of the NAD(+)-dependent enzymes remains unknown (By similarity).  Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity).  The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity).  Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity).
What are the official names of this protein?
Cytochrome P450 monooxygenase ARMGADRAFT_1018420, Melleolide biosynthesis cluster protein ARMGADRAFT_1018420.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YK44_CERS4
Sequence: MIVTTTPNIEGYQIATYHGIVTGEAILGANVIRDLFAGITDFIGGRSGAYEKELGRARETALSEMEEAARAKGANAVVGVDLDYEVINNMLMVSASGTAVTIA
What are the official names of this protein?
UPF0145 protein RHOS4_20440.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PLP_BPSAV
Sequence: MNEPIDPKSFPSQPLSPYIPMHHIGKGPYKTIFNVLSLNRDHIHWEDYLYKHTPCELVANPETNQQVWFKREDYFAPLSCYMNGKQGINGSKLRQAIWLMVEHLKAGGSPDLIHGTVVGSPQSPMATAVSRHFGGKTTTVLGATKPTTCMNHDMVKMSAWFGSEFNFVGSGYNSTIQPRCKKLIEQQNPKAYYLEYGITLDHTLHSPERIAGFHMLGGEQVANIPDHITDLIIPAGSCNSCTSILTGLAMHPKPNLKNVYLIGIGPNRLDFIESRLRIIGKQANLPHITDFTRCYHDNPDYVYGKKDLQHASKSVSLAGLLMGIREKGESEITLPRFAVHHWDLHTTNWVRYNDLMDYQWGDIELHPRYEGKVMTWIQQHKPELLNENTLFWIVGSKPYIEPMKAACPELSMPEQVPVNEFTPD
What is the function of this protein?
Converts 5-O-serinylthymidine (O-SerT) into 5-aminoethoxy-2'-deoxymethyluridine (5-NeOmdU) as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-NeOmdU substitutes for about 40% of the thymidines in the viral DNA (PubMed:34522950, PubMed:29555775).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
O-seryl-dTMP PLP-dependent decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal-phosphate-dependent aminodecarboxylase family.
Protein: SPIKE_CVCAK
Sequence: MIVLILCLLLFSYNSVICTSNNDCVQGNVTQLPGNENIIKDFLFHTFKEEPSVVVGGYYPTEVWYNCSRSATTTAYKDFSNIHAFYFDMEAMENSTGNARGKPLLVHVHGDPVSIIIYISAYRDDVQPRPLLKHGLLCITKNKIIDYNTFTSAQWSAICLGDDRKIPFSVIPTDNGTKIFGLEWNDDYVTAYISDRSHHLNINNNWFNNVTILYSRSSSATWQKSAAYVYQGVSNFTYYKLNNTNGLKSYELCEDYEYCTGYATNVFAPTVGGYIPHGFSFNNWFMRTNSSTFVSGRFVTNQPLLVNCLWPVPSFGVAAQQFCFEGAQFSQCNGVSLNNTVDVIRFNLNFTALVQSGMGATVFSLNTTGGVILEISCYNDTVSESSFYSYGEISFGVTDGPRYCFALYNGTALKYLGTLPPSVKEIAISKWGHFYINGYNFFSTFPIDCISFNLTTGDSGAFWTIAYTSYTDALVQVENTAIKKVTYCNSHINNIKCSQLTANLQNGFYPVASSEVGLVNKSVVLLPSFYSHTSVNITIDLGMKRSGYGQPIASTLSNITLPMQDNNTDVYCIRSNRFSVYFHSTCKSSLWDDVFNSDCTDVLYATAVIKTGTCPFSFDKLNNYLTFNKFCLSLNPVGANCKFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGITGVGIIRQTNSTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAHAAVIDGAIVGAMTSINSELLGLTHWTTTPNFYYYSIYNYTNERTRGTAIDSNDVDCEPIITYSNIGVCKNGALVFINVTHSDGDVQPISTGNVTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEIDSMLFVSENALKLASVEAFNSTETLDPIYKEWPNIGGSWLGGLKDILPSHNSKRKYRSAIEDLLFDKVVTSGLGTVDEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANDDKMAMYTASLAGGITLGSLGGGAVSIPFAIAVQARLNYVALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAIHQTSQGLATVAKVLAKVQDVVNTQGQALSHLTLQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWSGICASDGDRTFGLVVKDVQLTLFRNLDDKFYLTPRTMYQPIVATSSDFVQIEGCDVLFVNATVIDLPSIIPDYIDINQTVQDILENFRPNWTVPELPLDIFNATYLNLTGEINDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLLIGLVVIFCIPILLFCCCSTGCCGCIGCLGSCCHSICSRRQFESYEPIEKVHVH
What is the function of this protein?
S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection.  Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion.  S2 region belongs to the class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly.
Protein: GATB_BACCZ
Sequence: MNLETIIGLEVHVELKTNSKIFSASPTEFGAEPNTQTSVIDLGYPGVLPTLNKEAVNFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGKKKRIGITRLHLEEDAGKSTHTADGSLVDYNRQGMPLIEIVSEPDMRTPEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEKFGTKAELKNLNSFTYVQKGLEHEQVRQEKELLSGGIIQQETRRYDEATKKTILMRVKEGSDDYRYFPEPDLVELYIDDEWKEAVRASIPELPDARKARYVAELGLPAYDAHVLTLTKEMSDFFEATVADGADAKLTSNWLMGEVLAYLNKQQKELKDVALTPAGLSKMVQLIEKGTISSKIAKKVFNELIEKGGDPEEIVKAKGLVQISDEGTLRKVVTEILDNNEQSIEDFKNGKDRAIGFLVGQIMKATKGQANPPLVNKILLEEINKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PEX27_YEAST
Sequence: MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPIVLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVTSANEHTSAV
What is the function of this protein?
Required for regulation of peroxisome size and number.  Also promotes peroxisome division and biogenesis.
What are the official names of this protein?
Peroxisomal membrane protein PEX27, Peroxin-27.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein.
Protein: EPMB_BUCAP
Sequence: MKHYNTKKLNREKDSWLYEISNSIVEPKKLLKFLHLEKYPKYYDSKPKKVFPFRVPYSFASRMKKNDPKDPLLLQVITKNQEFLNNLQFNEDPVKEKKDIVLPGLLHKYKDRVLWILKTNCAINCRYCFRKHFPYEKNKGNKKNWIQILHYISQNIELNEVILSGGDPLMAKDHELLWLITSLSKIKHIKRLRIHTRLPIVIPNRITSDLCQIFSNSVLKIIIVTHINHPQEINEQLSDSLLKLKKSNVILLNQSVLLKNINDNAIILAELSSRLCENNIIPYYLHILDKVKGTSHFLVSNKKAKSIISDLMKMISGFLVPRLVFDNGSKDNKLIII
What is the function of this protein?
With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  EpmB appears to act before EpmA.  Displays lysine 2,3-aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity).
What are the official names of this protein?
L-lysine 2,3-aminomutase, LAM, EF-P post-translational modification enzyme B.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. KamA family.
Protein: NUOC_VESOH
Sequence: MQDLKTSLVEVFGKTNLVESFDELTLTVGSQNIIKTCLKLRDFFSFDTLIDLCGVDYLTYGQSDWNGNASASGFSRGRSHQGLKDIHEERFAVVYHLLSVSKNKRIRVKSFVDEVEPIIKSVTDIWASADWYEREAFDLMGILFENHTDLRRILTDYGFTGHPLRKDFPMIGEVEMRYDEDLCRVIYEKVSIEPNVNVPRVIRK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RR4_AGRST
Sequence: MSRYRGPRLKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKRSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVNIPSFRCKPRDIITTKDNQRSKGLVQNYIASSDPGKLPKHLTIDTLEYKGLVNKILDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GEMI2_DICDI
Sequence: MDEFQSKAFEVGEEIEPDDNEPLTGEEYLQRVKWHSNRCPSVVVADIDYSKIKVTIPSNSYFTLPPSITKCKKELLPTPTWEKEFLNDFSEFRQKLQYIKSNRPSNNNNNNNNNNNNNNNNNNNNNLIPQLPHINDKRYWYIFCFGSNGNNNNNNNDIKMKDFNDNQEDDDDDENNEDYEYNENKEEEEEEEEEEEEEEEVEEEEEEEEEEEEVVDYSTKKPTLGNKPTMDILCRLDHVLTVALVNYHIEWLEKREFTQERSYWLYMLLSLLEKPIDPDTCSNLRSCIRRLSVFRSKITNLNDPNLPSINILFTIIAKYFDQLEPSDILYL
What is the function of this protein?
May play an essential role in spliceosomal snRNP assembly in the cytoplasm and may be required for pre-mRNA splicing in the nucleus.
What are the official names of this protein?
Gem-associated protein 2, Gemin-2, Component of gems protein 2.
What is the protein family that this protein belongs to?
Belongs to the gemin-2 family.
What are the subcellular locations of this protein?
Nucleus, gem. Cytoplasm.
Protein: YAEH_SALPK
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAKSVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILDDLRHLESVVANKISEIEADLDKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: Y652_STRP1
Sequence: MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFSEGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SPy_0652/M5005_Spy0539.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RL18_EDWI9
Sequence: MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAISEQLKYTGNKEAAAAVGKAIAERALEKGVKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HIMB_ASPJA
Sequence: MPRHERGGSGTSSSDLRLRKACDRCHAQKLGCQREAIGAKCVRCEKADKPCTWSISLRNRRASTRKEQLPVHAQQQQQQQQQHQHQPQHATMARNENNEEQAQEDDNDDEDEDILYSDQLTPSEAIPELHSPLGDPHNRLASESLDPTTMPIDLTSFLISDGGLGLMTPSLTNPGSWLGETQLGTTTTTTTAITTATLIGEPPRFWSSATGGLPHTPSAGGLTTIDLPPAAFEMNLPGVPPSYTPSHQPDQPPPPKTGTPALSDPQWLKELFDNNARLYRNWHAVSSNMTTNQTINPLFPMSTTSQSHPSSAAFADEAVQLSTQLIHILRGLLHQHHESTGHRPPTTPKPRARAEDLDPDHSGLDPGSLLIVLSSYFRILEIFTMLSHALEATAAATGSTTHYHTPRATPPILRLPAIVVGSLDLASNTSLSTVLFLEVIEDLLTTLATLVLSIAQWPSHPHHATSRREPGWQGSDLHAGSDRLGLQIQGKEDEIRRVIRAIRARLGRKGDKAGV
What is the function of this protein?
Transcription factor that, with himD, probably co-regulates the him gene cluster that mediates the biosynthesis of himeic acid A, a ubiquitin-activating enzyme (E1) inhibitor.
What are the official names of this protein?
Transcription factor himB, Himeic acid A biosynthesis cluster protein B.
What are the subcellular locations of this protein?
Nucleus.
Protein: E3B14_ADE03
Sequence: MQAMLPVILILLLPCIPLASTATRATPEQLRKCKFQQPWSFLDCYHEKSDFPTYWIVIVGIINILSCTFFSITIYPTFNFGWNSPNALGYPQEPDEHIPLQHIQQPLALVQYENEPQPSLPPAISYFNLTGGDD
What is the function of this protein?
Down-regulates the EGF receptor and prevents cytolysis by TNF.
What are the official names of this protein?
Early E3B 14.5 kDa protein, Early E3B 15.2 kDa glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_14 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: EFG_STRMU
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKDHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDAQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGAEDDFEGIIDLVTMKAEIYTNDLGTDILIEDIPADYLDQAKEYREKLIEAVAETDEDLMMKYLEGEEITETELKAAIRKATINVEFFPVLAGSAFKNKGVQMMLDAVVDYLPSPLDIPPIKGVNPDTDEEEERPASDDEPFAALAFKIMTDPFVGRLTFFRVYSGILNSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKETTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRQATQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFVPAVEKGLIESMANGVLAGYPIVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAKPVILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNSQIVRAFVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQEEIIKKNAGEA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_RHIEC
Sequence: MSAPRTLYDKIWDDHLVDEQADGTCLLYIDRHLVHEVTSPQAFEGLRMSGRKVRAPEKTLAVVDHNVPTSPDRHLGIKNEESRIQVEQLAKNAAEFNVEYYSENDKRQGIVHIIGPEQGFTLPGMTIVCGDSHTSTHGAFGSLAHGIGTSEVEHVLATQTLIQKKAKNMLVQVDGQLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAPDEITFEYIKGKPRAPKGEALEQAIAYWKTLKSDEGAHFDRIVKLNAAELPPIVSWGSSPEDVVSVQGIVPNPDEIQDETKRASKWRALDYMGLKPGTKMTDIAVDRVFIGSCTNGRIEDLRAAAKVVEGKTVASTVNAMIVPGSGLVKEQAEAEGLDKIFKAAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPTMAAAAAIAGHFVDIREWN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.