PharMolix/UniProtQA huggingface dataset:
Protein: RPAB1_HUMAN
Sequence: MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1, DNA-directed RNA polymerase II 23 kDa polypeptide, DNA-directed RNA polymerase II subunit E, RPB5 homolog, XAP4.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
Protein: RNC_LISMH
Sequence: MNQWEELQESVGFDFKDVELLKQAFTHSSYVNEHRRENVKDNERLEFLGDAVLELTVSDYLFNKYPDMAEGHMTKMRAAIVCEPSLVEFAEAVHFSKYVRLGKGEEKAGGRTRPALLADVFESFIGALYLDNGIDKVVTFLERVIFPKIDAGAYLQTVDYKTQLQEIVQRDRDVLIEYDILGETGPAHNKAFDAQVIVNGQVLGKGSGRTKKQAEQSAAQFAINQLTHR
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_LEPBL
Sequence: MAQSKPVKKIVLAYSGGLDTSVILTWLKETYGCEVIAFTADVGQKEELSGLEEKGIKTGASKVYIQDLRLEFARDFIFPAIQGNALYEMRYLLGTSLARPLIAKAMVEVAEKEGADAFAHGATGKGNDQVRFELGVKSLAPEKTIIAPWRIWNFGGRSDLIEYAKSKGIPVSITVEKPYSMDRNLMHISYEGGILEDPYREPDEKMFLLTTSPEKAPDAPEYLELDFQEGNCVAINGKKLNPYEVMEALNTIAGKHGVGRVDIVENRLVGIKSRGVYETPGGTVLFLAHRDLESITIDRDTQHHKDKLSIEFAELIYNGHWFSSRMKAVRAFITETQRYVTGAVKVKLYKGTCSIVGRKSSVSLYNPKMATFEKEELYNQKDAEGFINIYGLPAQETARLRKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRG_YERPB
Sequence: MHVTLVEINVKEDKVDQFIEVFRANHLGSIREAGNLRFDVLRDEHIPTRFYIYEAYTDEAAVAIHKTTPHYLQCVEQLAPLMTGPRKKTVFIGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPI_BACSU
Sequence: MDLNLRHAVIANVTGNNQEQLEHTIVDAIQSGEEKMLPGLGVLFEVIWQHASESEKNEMLKTLEGGLKPAE
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: LPXC_STRM5
Sequence: MIQQRTLKNTIRATGVGLHSGDKVYMTLRPAPVNHGIVFRRVDLDPVVEVPAKAELVTEVTLCTGLTCNDAKIQTVEHLMSALAGLGVDNIIVELSSAELPIMDGSAGPFVFLLQSAGIVEQDAPKRFIRVLKTVEVTEGDKVARFTPYEGYKLGFTIQFDHPMIPAKQSRQEIEFSTLAYTKEISRARTFGFMRDLEYMRERNLGLGGSMDNAIVLDEFRVLNEDGLRYADEFVRHKILDAIGDLYLAGGQVLGAYEGFKSGHALNNKLVRALMADATAWEWVSFDSPATPDPVEYATPAYA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DEF2_APIME
Sequence: MKFFVLFAILIAIVHASCASVPKVVYDGPIYELRQIEEENIEPDTELMDSNEPLLPLRHRRVTCDVLSWQSKWLSINHSACAIRCLAQRRKGGSCRNGVCICRK
What is the function of this protein?
Antibacterial peptide mostly active against Gram-positive bacteria.
What are the official names of this protein?
Defensin-2.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_METSB
Sequence: MAKEATRVRRRERKNIVSGVAHVNSTFNNTMITITDAQGNTISWSSAGTMGFKGSRKSTPYAAQMAAEDCARKAAEHGMRTLEVEVSGPGSGRESALRALQAAGFTVTSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RISB_CHLAA
Sequence: MTIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELPLVCHRLAESSRYDAIIALGAVIRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDNIEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HIS1_PSECP
Sequence: MLRVAVPNKGSLSEAASAMLSEAGYRQRRDSRELVMVDPDNDIEFFFLRPRDIAVYVGRGTLDVGITGRDLLLDAEVEAEELLPLGFAASTFRFAGPVGDFASAEELEGKRLATSYDGLLRGYLAERGINAKVVRLDGAVESSVRLGVADAIADVVETGNTLKAAGMEIFGDPILKSEAVLIRRAGGTTNGTAKEVDVLIRRLQGVLVARQYVLMDYDIRKELVEKAAALTPGLESPTVSPLRDSDWVAVRSMVPKKETNRIMDELYDLGARAILVSSIHACRI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXC2D_CUPSA
Sequence: GFGTILKALAKIAGKVVKKLATKPGATYMLKQNLQ
What are the official names of this protein?
Cupiennin-2d, Cu-2d.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RRAAH_BURP6
Sequence: MMFATTDLCDAHEDRLAAGTLRVLEPVFRPFGGVRRFAGPAATLKLFEDNSLVRTALEQDGAGRVLVVDGGGSLRCALVGGNLGKLAEKNGWAGIVVNGCVRDSDELAECRVGVLALAAHPRKSDKRGAGVSDAPVDVRGTRIVPGDWIYADADGVLVSDDALLE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: NU6M_AEDAE
Sequence: MMTLIMLISLITSFIFMQMKHPLAMGLMLLIQTFLTSLLTGMFVKTFWFSYVLFLIFMGGMLVLFIYVTSLSSNEMFSLSMKLFFLSLSMILMFIVFSFFFDKSIISMFINNNEMNNLFSTNSLMMEDLISLNKMYNFPTNLITLLLINYLFLTLLVTVKITKKNYGPLRPMN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: EM55_MOUSE
Sequence: MTLKSSEGEGGNSMRTALSDLYLEHLLQKRNRPETSLNQSNVTTEDMYTNGSPAPGSPAHAKGQEARRVRLIQFEKITEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKVIANQQSRLPALQMFMRAQFDYDPQKDNLIPCKEAGLKFVTGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASVAHSAPSEAPSCSPFGKKKKCKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNGLLSHNPEKFAYPAPYTTRPPKKSEEDGKEYHFISTEEMTKNISANEFLEFGSYQGNMFGTKFETVHQIHKQDKIAILDIEPQTLKTVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSSPQWVPVSWVY
What is the function of this protein?
Essential regulator of neutrophil polarity.  Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
What are the official names of this protein?
55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (PubMed:16829577). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (PubMed:17584769). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies, and at connecting cilium (CC) (PubMed:17584769). Colocalizes with NF2 in non-myelin-forming Schwann cells (By similarity).
Protein: YBEY_RICAE
Sequence: MINVEIVRNYNKWREYKQINKSLIKKITQNILLRFDNFSKIKQFELSILLTNAAEILTLNKQFRNIEKATNVLSFPSNELNWQDLYSKLEFLDDSDYMHLGDIAFCYEVIYNESCEQHKTFENHFIHLLIHSILHLIGFDHQNDTEANIMENLEIEILSYFGIFPPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RODZ_ERWT9
Sequence: MNTEATQEKSNVNSTGERLRTAREQMGLTQQNVAERLCLKLSTIRDIEEDNSPASLASTFLRGYIRSYARLVHVPEEELLPMMAKQAPVRDAKVEMMQSYSLGKQRKKRDGWLMIFTWLVLFVVLGLTGAWWWQNHKAAQDDLVSMGDQNASVEEDGRQSIALSDDNANGGAQTAIPLDNKPATANNAPSSVTATSDNGTPAATAQSSQVTASNAAPAANAVNDNTPPVAVAPSQAATNSSAAAPLPTGSAAVSRPAADANAMMMTFSRDCWLDVTDATGKKLFSGIQRSGGKLSLAGKAPYHLKIGAPAAVQIEYQGKPVDLGRFIRTNQVARLTVGAP
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: ZDH1_STAAC
Sequence: MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGGVGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHITTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHQLLEKQSMIGKLVINI
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein SACOL2177.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: TOP2A_PIG
Sequence: MEVSPLQPVNENMQVNKTKKNEEAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQMWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRLLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESDNEKEADKSDSVADSGPTFNYLLDMPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKAKGKKTQMAEVLPSPCGKRVIPRVTVEMKAEAEKKIKKKIKSENTEGSPQEDGMEVEGLKQRLEKKQKREPGTKTKKQTTLPFKPIKKAKKRNPWSDSESDISSDESNFNVPPREKEPRRAAAKTKFTVDLDSDEDFSDADEKTRDEDFVPSDTSPQKAETSPKHTNKEPKPQKSTPSVSDFDADDAKDNVPPSPSSPVADFPAVTETIKPVSKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGAKKDPDLDSDVSKKPNPPKPKGRRKRKPSTSDDSDSNFEKMISKAVTSKKPKGESDDFHLDLDLAVASRAKSGRTKKPIKYLEESDEDDLF
What is the function of this protein?
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (By similarity).  May play a role in regulating the period length of BMAL1 transcriptional oscillation (By similarity).
What are the official names of this protein?
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus. Nucleus, nucleolus.
Protein: ACDH1_AZOSB
Sequence: MKKIKCALIGSGNIGTDLIYKIKRSPVLEPVWMVGIDPASEGLARARELGLKTTADGVDGLLPHVLEDGIQIAFDATSAYVHAENSRKLNELGVMMIDLTPAAIGPLCVPPVNLRQHADRVEMNVNMISCAGQATIPIVNAVSRVQGVEYAEIVASLASKSVGPGTRANLDEFTYTTSSAIEKVGGAKKGKALAIINPAEPPLIMRNTIYCLTESAPDQARITESILQMIGEVQKYVPGYRLVNGPSYDGNKVSVFMEVAGLGDYLPKYAGNLDIMTAAATRTAEMFAEEILAGKIKLKTAEVA
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: NANE_PHOPR
Sequence: MNKTQENALKALQQGFVASCQPVDDGPMDSPMIVAAMAQAAVAGGVAGIRIEGIENVKAVRPHVNVPIIGIIKRDLEHSDVRITPFIEDVYALKAAGADVIAIDATHRVRPTSVEDLIDAIHSVGCLAMADCSTYDEGMYCQARGVQIIGSTLSGYTGGPVPAEPDFDLITRLKQAGCRVMAEGRFNTPELAGKAIEAGAFCVTVGSAITRVEHICSWFQAEVEHAHQAQSEAVA
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: NQRD_HAEIE
Sequence: MSGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVSLIRNYIPNSIRIIVQLAIIASLVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKLFGMTIFETIQNGGWYQANGLFLLAPSAFFIIGFVIWGLRTWKPEQQEK
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_STRP7
Sequence: MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNJ10_CAEEL
Sequence: MFVLNRSSGLIHRSVPLLAQVSTPTTSTTKLAQLHTTHALSKEDYYKTLGVDKKSDAKAIKKAYFQLAKKYHPDVNKTKEAQTKFQEISEAYEVLSDDTKRQEYDAYGSGGGPAGGRGGAGGFHHHGNVDVNEIFRRAFGGGGGMGGFNFDNFAQSAFGHSAAQEMVMDISFEEAVRGATKNVSVNVVEDCLKCHGTQVEPGHKKTSCPYCNGTGAVSQRLQGGFFYQTTCNRCRGSGHYNKNPCQECEGEGQTVQRRQVSFNVPAGTNNGDSLKFQVGKNQLFVRFNVAPSLKFRREKDDIHCDVDISLAQAVLGGTVKVPGINGDTYVHIPAGTGSHTKMRLTGKGVKRLHSYGNGDQYMHIKVTVPKYLTAEQKQIMLAWAATEQLKDGTIKGLEKNQKTEEKETKKNEEKKSEGASESQKRRSEPVAENAETIDENQENEGFFEKIKRKIFG
What are the official names of this protein?
DnaJ homolog dnj-10, DnaJ domain protein 10.
Protein: ALGLR_THEMA
Sequence: MNTDDILFSYGEEDIPLKALSFPIFETTNFYFDSFDEMSKALRNGDYEFVYKRGSNPTTRLVEKKLAALEECEDARLVASGMSAISLSILHFLSSGDHVVCVDEAYSWAKKFFNYLSKKFDIEVSYVPPDAERIVEAITKKTKLIYLESPTSMRMKVIDIRKVTEAAGELKIKTVIDNTWASPIFQKPKLLGVDVVVHSATKYISGHGDVMAGVIAGDVEDMKNIFVDEYKNIGPVLSPIEAWLILRGLRTLELRMKKHYENALVVSDFLMDHPKVLEVNYPMNPRSPQYELASSQMSGGSGLMSFRLKTDSAEKVKEFVESLRVFRMAVSWGSHENLVVPRVAYGDCPKKDVNLIRIHVGLGDPEKLVEDLDQALKKI
What is the function of this protein?
Catalyzes the racemization of L-alanine to D-alanine, and of L-glutamate to D-glutamate.  The activity is low, but likely physiological since T. maritima lacks canonical alr and murI genes, while D-alanine and D-glutamate are essential components of peptidoglycan.  Also displays a more efficient cystathionine beta-lyase (CBL) activity, cleaving cystathionine to homocysteine and pyruvate; however, this reaction seems not to be physiologically relevant since T. maritima possesses an O-acetyl-homoserine thiolase (MetY) that bypasses the need of CBL for methionine biosynthesis.  Is not able to produce cystathionine, using either O-acetylhomoserine or O-succinylhomoserine, plus L-cysteine as substrates, and thus does not possess cystathionine gamma-synthase (CGS) activity.
What are the official names of this protein?
L-alanine/L-glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: ANR37_HUMAN
Sequence: MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC
What are the official names of this protein?
Ankyrin repeat domain-containing protein 37, Low-density lipoprotein receptor-related protein 2-binding protein, hLrp2bp.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: POTC_MYCPN
Sequence: MFKMKSCKLWLRGSFFVIVLVLIYLPLIIVVLVSFNGSSTRGNIVLDFGNVLNPNPDAKSAYLRLGEADFAIPLLNSVIIGLITVIVSIPIAIMTAFALLRSRQWLNKTVFGIANFSLATPDIITGISLVLLFANTWLSFNQQLGFFTIISSHISFSVPYALVLIYPKMQKLNRNLILASQDLGYSPIATFFHITLPYLLPSILSAILVVFATSFDDYVITSLVQGSVKTVASELYSFRKGIKAWAIAFGTILILVSILAVLLVTLHKYLRFKHKEMLRVKQWKNS
What is the function of this protein?
Required for the activity of the bacterial transport system of putrescine and spermidine.
What are the official names of this protein?
Spermidine/putrescine transport system permease protein PotC homolog.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DYR7_ECOLX
Sequence: MKISLISATSENGVIGNGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFDSMGVLPNRKYAVVSRKGISSSNENVLVFPSIEIALQELSKITDHLYVSGGGQIYNSLIEKADIIHLSTVHVEVEGDINFPKIPENFNLVFEQFFLSNINYTYQIWKKG
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase type 7, Dihydrofolate reductase type VII.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: UPPP_BORHD
Sequence: MENVLRVVILGFIQGIAEFLPISSSGHLLLLKKFMHIDLPIVFDIYLHLATVLVVMIYYCRRILELVAVLVKFVLGKTTECDFAKLRLILLILIITIITAFIGIFIEMFKGLFTLNLVLINFIVTSILLFLLESRIVIFDLKRNILLAGCLIGTMQGIGAMPGISRSGITIFASVLLGFSRSESFEISFLSLIPIVFGSLLLKYKELFESDMLFSIFEINLGAIIAFLVGLFSISLFVKMLQDSKLYYFSVYLIILVSLVYFLF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OKS_ALOAR
Sequence: MSSLSNASHLMEDVQGIRKAQRADGTATVMAIGTAHPPHIFPQDTYADFYFRATNSEHKVELKKKFDRICKKTMIGKRYFNYDEEFLKKYPNITSFDEPSLNDRQDICVPGVPALGAEAAVKAIAEWGRPKSEITHLVFCTSCGVDMPSADFQCAKLLGLRTNVNKYCVYMQGCYAGGTVMRYAKDLAENNRGARVLVVCAELTIIGLRGPNESHLDNAIGNSLFGDGAAALIVGSDPIIGVEKPMFEIVCAKQTVIPNSEDVIHLHMREAGLMFYMSKDSPETISNNVEACLVDVFKSVGMTPPEDWNSLFWIPHPGGRAILDQVEAKLKLRPEKFRATRTVLWDCGNMVSACVLYILDEMRRKSADEGLETYGEGLEWGVLLGFGPGMTVETILLHSLPLM
What is the function of this protein?
Catalyzes the iterative condensations of 8 molecules of malonyl-CoA to produce aromatic octaketides, SEK4 and SEK4b, the products of the minimal polyketide synthase for the benzoisochromanequinone actinorhodin.  May be involved in the biosynthesis of the octaketide barbaloin.
What are the official names of this protein?
Octaketide synthase 1, OKS.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: GUN15_ARATH
Sequence: MSCISSQCFITIKSICIVLLLSITCGAVSANSNYGEALTKSLLYFEAQRSGKLPLDQRVIWRGDSALRDGSDAHVDLTGGYYDAGDNMKFGFPLAFTTTMLAWSSVEMESQLKAHQEHGNTLAALRWATDYLIKAHPEPNVLYGQVGDANLDHACWMRPEDMTTPRPSYRIDPQHPGADLAGETAAAMAAASLAFAPSDSAYAKTLISHAKELFEFAKDYPGVYHNSIPNAGGFYPSSGYEDELLWAAAWLHRATGDQTYLDHLTQASNSGGARSVFAWDDKFLGAQVLVAKLVFEGKVKNEGKMIEYKSMAEQFICNCAQKGFNNVKKTPGGLLWFLPWDNLQYTATASFALATYAKYLEAAQTSIQCPNGDVLQASDLLNLARAQVDYILGSNPKKMSYMVGYGTNYPKRPHHRGASIVSIKNDPKPVTCNGGFEAWYNNPKPNPNLLVGAIVGGPDEYDAYGDERSDFQHGEPDTVTVAPLLGVLAAIA
What are the official names of this protein?
Endoglucanase 15, Endo-1,4-beta glucanase 15.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.