PharMolix/UniProtQA huggingface dataset:
Protein: CYB_SORAC
Sequence: QILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGIHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILALTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VF233_ASFP4
Sequence: MILIASPFSLAHLEYLHTWHVTIKNIAQQHGLDIKVAIVVSTSHLNTFLPISTALNIECITFPGCGIKEIDLLWARIKLFQHYCAIGARLLWLVSADIRPPVSTWPAIADSLKKGADAVVIPYPSRWNNLIPTVIKEIVVHQKKCLVAVDARHLDTDTQIVGAGMGCIVLTLKALMVRLSIGKQPIKILWPDLHGTAEGIPLEGVEVGWFLNAYAHKLNIRCLGADHIAQHLT
What are the official names of this protein?
Uncharacterized protein H233R, pH233R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H233R family.
Protein: LYSC2_CANLF
Sequence: KIFERCELARTLKNLGLAGYKGVSLANWVCLAKWESNYNTRATNYNPGSKSTDYGIFQINSRYWCNDGKTPRAVNACHISCSALLQDDITQAVACAKRVVSDPNGIRAWVAWRAHCENRDVSQYVRNCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, spleen isozyme, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: YQGF_GLAP5
Sequence: MSQTVLAFDFGTNSIGCAVGQSITGTAQGLPAFKAQDGIPNWEQIGKVIAQWQPDLLVVGLPLNMDGTEQPLTQRAKKFANRLNGRFNLPVELQDERLTTVEAKSEIFARGGFKALKKGKVDAISACLILESWFEQQS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_STRMU
Sequence: MEIIEKAPAKINLGLDIAGKYQDGFHELSMIMASVDLNDYLTITEIAEDKIVVESNNCKLPLNRKNDVYKAAHLLKRRYHISTGLKISLQKKIPICAGLGGGSSDAAATLRALNCLWKLNLSPKELIDVGFEIGSDVPYCIEAGCALISGKGEIVEPLATTLSTWVVLVKPDFGISTKTIFKEIDMATISRVDIPALKEALLANYYEDALQFMGNSLEDITIAKKPFIQKIKGRMIKCGADIALMTGSGPTVFALCRTEKRADRVVNSMKGFCKEVYKVRML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HIGB2_MYCTU
Sequence: MNVPWENAHGGALYCLIRGDEFSAWHRLLFQRPGCAESVLACRHFLDGSPVARCSYPEEYHPCVISRIALLCDSVGWTADVERISAWLNGLDRETYELVFAAIEVLEEEGPALGCPLVDTVRGSRHKNMKELRPGSQGRSEVRILFAFDPARQAIMLAAGNKAGRWTQWYDEKIKAADEMFAEHLAQFEDTKPKRRKRKKG
What is the function of this protein?
Putative toxic component of a type II toxin-antitoxin (TA) system.  Its cognate antitoxin would be HigA2.
What are the official names of this protein?
Putative toxin HigB2.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial HigB family.
Protein: PANC_PSESM
Sequence: MNTVKTVLELRAAVARARSEGKRIALTPTMGNLHSGHAALVSKAAQRADFVVASIFVNPLQFGPNEDLATYPRTLAADQEKLLQAGCNLLFTPGVEEMYPHGMADQTLVSVPHLSQGLCGASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIRAMVRDLNMPIQIIGEPTVRADDGLALSSRNGYLDEAQRAAAPALYQAIRQTAEAISAGEQDFETLLNSKKQQLQAAGFRIDYLEIRNADSLRPTTAEDPDLVILAAAFMGKTRLIDNLHLTRG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEP3_KLULA
Sequence: MDKLRLLGSYLRKSPLTSTVSEPGIKISPKQFTFSVRVRDKDRPSKISTTKINEPASKLENTSTVVHNEYLNSLQLPYLARTSLRVSKYDYKRAAQFSNTLKRTLKTQDAHERIFSISSEDVAKLISSLFQVSEDNVSLVAKKRFFERECFTEIPKITEEVLSDIQEFEDYIGLLTHTKFHHKGSSLQDGIIPKLLKNLLHPSNLRIAPLKTASVFNDVIYYYGNKNNFATCRELYAQMKSEGIAPNVQTYNLMLRNLLRNSRLIKQQLPYREAIFYLERMKKENISADVITWNTCYFLLKDNISRAIFLEKMVERGVPLTYHLLYGILEEEDIPFNVIIDFLRENDIPVDTKIIKICHRSLIKRDKFQASWKLMEYARHLNFRVKDPFFLEEYLRQFSEKGRMDMCIMTVNTFKATFEVEPTLHCYDLLFKCLVRQGYSSEFSRVYQMLLINLKEHTGGHVVMNYWIAKCRAIMNSNIKTIPTHDSITRLDALAKRCIWDKRGIKWNCWLEYSEYRNVFRRLGSVPYQSNSRDQLDKHEVAKSSKKKVKYLKKLKETAIRNKQSHDAAYRNDYYSALKNDLINRGIIEEQAK
What is the function of this protein?
Required for respiration.
What are the official names of this protein?
ATPase expression protein 3.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RSMH_MYCBP
Sequence: MQTRAPWSLPEATLAYFPNARFVSSDRDLGAGAAPGIAASRSTACQTWGGITVADPGSGPTGFGHVPVLAQRCFELLTPALTRYYPDGSQAVLLDATIGAGGHAERFLEGLPGLRLIGLDRDPTALDVARSRLVRFADRLTLVHTRYDCLGAALAESGYAAVGSVDGILFDLGVSSMQLDRAERGFAYATDAPLDMRMDPTTPLTAADIVNTYDEAALADILRRYGEERFARRIAAGIVRRRAKTPFTSTAELVALLYQAIPAPARRVGGHPAKRTFQALRIAVNDELESLRTAVPAALDALAIGGRIAVLAYQSLEDRIVKRVFAEAVASATPAGLPVELPGHEPRFRSLTHGAERASVAEIERNPRSTPVRLRALQRVEHRAQSQQWATEKGDS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_NATTJ
Sequence: MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEGESIATGLLDITLYRDDLSTLSEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAVIDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKELISVRLSEIDGEDRVMIEETVKE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: BSH_ARATH
Sequence: MKGLVSTGWKGPVKFRMPTAENLVPIRLDIQFEGQRYKDAFTWNPSDPDNEVVIFAKRTVKDLKLPYAFVTQIAQSIQSQLSDFRAYEGQDMYTGEKIIPIKLDLRVNHTLIKDQFLWDLNNFESDPEEFARTLCKDLGVEDPEVGPAVAFAIREQLYEIAIQSVASARESRLSKKGRRGSDHGSASKASGLSMDLMKLFSFKSSVVRKRKDLDVYEPVVDLLTSEEVDALEAREERHAR
What is the function of this protein?
Component of a multiprotein complex equivalent of the yeast SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
Chromatin structure-remodeling complex protein BSH, AtBSH, Protein BUSHY, SNF5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRM5_MACFA
Sequence: MVLWILWRPFGFSRRLLKLERHSITESKSLIPLAWTSLTQTLSESPGIFLLGQRKRFSTMPEIETHEGDSELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSRLMRSLRRAALQRPGIKRVIEDPEDKESRLILLDPYKIFTHDSFEKAGLSVLEQLNVSPQISKYNLELTYENFKSEEILRAVLPEGQDVTSGFSRVGHIAHLNLRDHQLPFKQLIGQVMIDKNPGITSAVNKINNIDNMYRNFHMEVLSGEQNMMTKVRENKYTYEFDFSKVYWNPRLSTEHSRITELLKAGDVLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLHNCKLNKVDQKVKIFNLDGKDFLQGPVKEELIQLLSLSKERKPSVHIVMNLPAKAIEFLSAFKWLLDGQPCSNEFLPIVHCYSFSKDANPAKDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPAAVLYKNQTKNPENHEDPPLKRQRTAEAFSDEKTQIASNT
What is the function of this protein?
Involved in mitochondrial tRNA methylation (By similarity).  Specifically methylates the N1 position of guanosine-37 in various tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: CRCB2_DESHY
Sequence: MASHILLVGIGGFCGAIVRYFFSRKLNSGKLPVGTLTVNLSGAFLLGAMAGANLSTTTTLLLGTGFLGAFTTFSTLKLEMAQLQLKKEHRLFILYTTITYGGGIALAYLGYWLGSFFR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TKNK_PIG
Sequence: MRSTLLFVAILALSLAWSLGAACEESQEQLMPGGGHSKKDSNLYQLPSSLLRRLCDSRSISLDGLLKMLSKASVGAKESSLPQKRDMHDFFVGLMGKRNIQPGTPVDGNQENAPSLGTFKYPPSVE
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.  Is a critical central regulator of gonadal function (By similarity).
What are the official names of this protein?
Neurokinin-B, NKB, Neuromedin-K.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_LEPBA
Sequence: MKINFTKMEGIGNDYVYIDATKNDIRLSPEQIQKLSDRNFGIGGDGVIFIRNSNSGEFQMDMYNSDGSSSEMCGNGVRCVGKFVYDHGLTKNQKPTIETGKGVLTLDLKTGTNGKVEMVTVDMGEPILKPSLVPIVWKGDEPVINQVIEVQGKQYHFTAVSMGNPHCVIYVDDADDFPVREIGPIIENHPFFPRRVNVEFVSIKGKDHLYQRTWERGTGETLACGTGACAVTVASILNGKTGRSVRIDLRGGTLHIEWQENGSVFMTGPAKEVFSGEVEI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_CHLTA
Sequence: MLMPKRTKFRKQQKGQFAGLSKGATFVDFGEFGMQTLERGWITSRQIEACRVAINRYLKRKGKVWIRVFPDKSVTKKPAETRMGKGKGAPDHWVVVVRPGRILFEVANVSKEDAQDALRRAAAKLGIRTRFVKRVERV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CAIE_SALHS
Sequence: MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQDLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: TRA2_DROVI
Sequence: MSTGLVNAREKEYLHLHRIDKHKCSHSSATSSPSSAASSESSRTRQRRSDGEVYGSRHNNYKSSSQHRRRSRSGSDSPQVRHYSGRTSRDRQRMRQARDHPQASRCIGVFGLNTNTTQQKVRELFNKFGPIERIQMVIDAHTHRSRGFCFIYFENLGDARVAKDACTGMEVDGRRIRVDYSITQRAHTPTPGVYMGRPSRPLGRRSRERDYSTRDTSRSRRRHRDESSSVSPYDSNRRKYRSRHRYDRSRSRTRSYSRSRSPRKPVRVQSRY
What is the function of this protein?
Required for female sex determination in somatic cells and for spermatogenesis in male germ cells.  Positive regulator of female-specific splicing and/or polyadenylation of doublesex (dsx) pre-mRNA.  Splicing requires an enhancer complex, dsxRE (dsx repeat element: which contains six copies of a 13-nucleotide repeat and a purine-rich enhancer (PRE)).  DsxRE is formed through cooperative interactions between tra, tra2 and the sr proteins, and these interactions require both the repeat sequences and PRE.  PRE is required for specific binding of tra2 to the dsxRE.  Protein-RNA and protein-protein interactions are involved in tra-2 dependent activation and repression of alternative splicing (By similarity).
What are the official names of this protein?
Transformer-2 sex-determining protein.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
Protein: LIPE_AERHY
Sequence: MKKKLIYAAVVSALLAGCGGSDDNKGDTSSYLDYLLTGSNAVGPSALAARAWDGTLKFSTETADLSNPVSAMSTLDGWSTTQAIQIVPVTSSGITVQAPTTAEFGASVAPLYLLEVTFDSTALRPSGVKKVLTYGVDFVVAASAWQAEPGSAQAVEPLPCLANDSGHRTAERQSRRCLKAGSDYGNYKNNAGSNAQEQTINGLIALQEGLFKAATGIATDHVIFSDWFGTQSGADVLVAVKGAAASVLKADPVTLDAAKLWKQDAWEHQPARHLYPGRDRPTCLPDPAGCRAVPAAEQKDAIATAFGPVLRSTRLLKRPRSIPVPSSCLTSSPHRRPQVPGARPRPSPGTVPSQPVRHRQCAEGVTRSDRRAGGGGRGSGPAGDADCRSDPPERAAGRGEQADWGDAHLRRQAAGRRAEHWSLQPAADAGRGAIRADACLRQGCPQHHHGCHHLSARRDLGQRERLRPGAGPDLEDLCRHAGGQEGGAGGDRSSAARRAWLRLSGSMDTVTTSDNPTPYLNLSYLTVARDNLKQSVAICWACVWRLAWPTPRAIGTAGSLKVHFLGHSLGASRVPTCCGRQPDHRQRASGCPVQVRYRWPGHAGSHSAAAAELADFGPTIKMGVLTSGSAELKAGFTAYAPNCTDGGAYLLRQRVPAEPGRGHSATAATRCRVQLCGPVGAGFG
What is the function of this protein?
The optimum chain lengths for the acyl moiety is C6 for ester hydrolysis and C6 and C8 for triacylglycerol hydrolysis.
What are the official names of this protein?
Extracellular lipase, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: VATE_THET8
Sequence: MSKLEAILSQEVEAEIQALLQEAEAKAEAVKREAEEKAKALLQARERALEAQYRAALRRAESAGELLVATARTQARGEVLEEVRRRVREALEALPQKPEWPEVVRKLALEALEALPGAKALVANPEDLPHLEALARERGVELQAEPALRLGVRAVGAEGKTQVENSLLARLDRAWDALSSKVAQALWG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: RECF_CHLSY
Sequence: MYVHHLFLRDFRNYRRLDLALAPATTLFYGPNAAGKTSLLEAIFYLATTRSPRLSSDRELVRWDAVGEAGTPPFARIAADVERRIGPVRLEVLVQRRADDDGQPLNGAQKLVRIDKRPARAIDLIGQLRVVLFTPTDLTLVDGPPAERRRYLDITLSQLDPHYVRTLAHYQKILLQRNSLLRAWREQRRVPRHVDAELAYWDQELAAAGGYLLAERLRAIVELNDLAGPLYQEMSGGEDRLQIEYAASCDLGTARDAGGLAERLLLAFAAQRSDELARGQTLCGPHRDDLIFTVAGINLGRYGSRGQQRSIALALKIGEAGLMRRRSGEAPVLLLDDVLSELDAQRRAHLLALIHHPDQQTLLTATDLSDFSADFLAAVRRYRVEDGQVFAG
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_VIBCH
Sequence: MALTKAELAEALFEQLGMSKRDAKDTVEVFFEEIRKALESGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVENIKVEK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DPEP1_ARTOC
Sequence: MAPERRSRLSDAGILVSLLALTSLVPVQAAVTTSKPDYAKRAERVLRSTPLIDGHNDLPFAIRRSTHDQIYDGKVPFETALKGQTDLPRMRKGRMGGQFWSVYVGCPSDPNTPIDFPTFATRDTLEQIDVARRLVDKYSKDLMYCDNPACAKKAFREGKIGSFIGIEGGHQVGSSIAALRQAFYAGARYMTLTHNCDNAWATAASTVRAGKPDLGMTEFGPALIKEMNRLGMLVDLSHVSHQTMRDVLKVTKAPVIFSHSSAYAVSKHLRNVPDDVLKTVAKNNGVVMVTFVRSFVNIDNPDSVTVDDIVKHIFHIAEVAGWDHVGLGGDYDGTTELPKGLEDVSKYPYLIEKVLEHGATEEQARKLIGENILRVWTEVEKIGKRIQNSGALPVEEVWQGRNWTQSLTKRSTFIPTESPTQLEFGCD
What is the function of this protein?
Hydrolyzes a wide range of dipeptides.
What are the official names of this protein?
Putative dipeptidase MCYG_02918.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Protein: YAF2_MOUSE
Sequence: MGDKKSPTRPKRQPKPASDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDRVEKDKSEKEAASKKNCHKKTRPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKAKSAPASSAAGDQHSQGSCSSDSTERGVSRSSSPRGEASSLNGESH
What is the function of this protein?
Binds to MYC and inhibits MYC-mediated transactivation.  Also binds to MYCN and enhances MYCN-dependent transcriptional activation.  Increases calpain 2-mediated proteolysis of YY1 in vitro.  Component of the E2F6. com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
What are the official names of this protein?
YY1-associated factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_TRIV2
Sequence: MANVIVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVKGQTFKLHLIPSGILYPDTECMIGCGTVIDPQVLIKELDQLESLNISTKNLLISETAHVTMPYHRLIDKASEERRGSHKIGTTGRGIGPTYADKSERTGIRVLDLMDPAALRDQLAWTINNKNLILEKLYNLPPLDTEEVVKEYLGYAERLRPHVVDTSLKIYDAIQRRRNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACVGTGLGPTMIDRVIGVSKAYTTRVGEGPFPTELDGELGELLCDRGAEFGTTTGRKRRCGWFDAVIGRYAVRINGMDCMAITKLDVLDELEEIQVCIAYEIDGDRCDHFPTSARQFARCRPIYKTLPGWQVPTSECRTLEDLPQQALDYLKFLAELMEVPIAIVSLGASRDQTIIVEDPIHGPKRALLHPDGTPASLLSA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_STRE4
Sequence: MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAYGHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLTITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLDGIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVGTLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSDRIPREY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: METK_DESVV
Sequence: MIPSKGKYYFTSESVTEGHPDKVADQISDAVLDVLLAQDPNSRVACETLVTTGMAVIAGEITTRGYADLPHVVRETIRNIGYNSSEMGFDWQTCAVISSIDKQSADIAQGVDRATNEDQGAGDQGMMFGFACDETATLMPAPIYWAHQLSQRLTEVRKDGTVDIFRPDGKTQVSFEYVDGKPVRINNVVVSTQHKDSASQADIIDAVKTHVIRPILEPSGFFDEKACDIFINTTGRFVIGGPMGDCGLTGRKIIQDTYGGMGHHGGGAFSGKDASKVDRSGAYMARYIAKNVVASGLAPKCEVQIAYCIGVAEPVSVLVSSQGTASVPDEVLTRAVREVFDLRPFHITRRLDLLRPIYGKTSCYGHFGRELPEFTWEHTDAAADLRTAAKV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMT3_YEAST
Sequence: MPYRVATGYSEKSTDDDLIWRTPIVKEELEDADNFLKDDAELYDKVKNESAVSHLDTIVMPIIFTVLGMFTRMYKIGRNNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEVYPDYIDYVKMRLFQAMFSSLCVPLAYFTGRAIGFSRLSVWLFTILVIFENSYATLGKFILLDSMLLFFTVSSYFCLAKFHTMRKSPFSARWWLWLCLTGLNLGCAISVKMVGLFIISVVGIYTISELWNLLSDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFKIHFDLLSNSGPGDSTMPSLFQASLNGTKVGKGPRDVALGSSIISIKNQALGGALLHSHVQPFPEGSEQQQVTVYGYSDANNEWFFQRIRGVEPWTDAENKTIEFVKGGEMYRLMHRLTGKNLHTHEVPAPISKSEYEVSAYGDVDLGDYKDNWIIEIVEQVGEEDPTLLHPLSTSFRIKNSILGCYLAQSGKHLPEWGFRQGEVVCLKHASKRDKRTWWNIETHENERLPQGEDFVYPKTSFFRNFMQLNSAMMATNNALVPNPEKFDGIASSAWQWPTLNVGVRLCEWSEKSIKYFLLGSPASVWPSSIAVCALIIHVIFLTLKWQRQCVILSDPVERDVFVMAAFYPLLAWLLHYMPFVVMSRVVYAHHYLPTLYFALMILSYYFDMITKRWATRNTGKFLRLGAYIVYGSIVIAGFFYFSPFSFGMDGPVDDYAYLAWLPTWQIVEDIRNT
What is the function of this protein?
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity.  Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins.  Seems to have redundant activity to PMT2.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FTSY_RICFE
Sequence: MISIFSKLKQSLSKTSNKISKGIDKIFYKKKLDTETLEELEELLIASDMSVSVVTNIIEEFKKVKFDKEIDSDTVKEALAELIEQQLSKSEIPFTLNENKLNVILVCGVNGAGKTTTIGKLAAMYGMQGKKVAVAACDTFRAAAVNQLSTWVDRANALLITGEESADPASVAYRAMEESIKQNIDILFIDTAGRLHNKKNLMDELSKIVKVIKKLDENAPTHSVLVIDAITGQNTYNQVEHFNDATNLTGLIVTKLDGSAKAGVLVGVVQKFNLPVYFIGIGEKIEDLKIFNRHDFAKSLVGL
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).  Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.