PharMolix/UniProtQA huggingface dataset:
Protein: MSRA_XANAC
Sequence: MLGIGAFKQRLPRPGEALPGREQALPLHNTHLVNGHPLRGEFTGLAQVQFGLGCFWGAERKFWNVPGVYTTAVGYAGGQTPNATYSEVCSGQTGHTEAVLVVFDDHAVSFAQLLRTFWESHDPTQGMQQGNDMGTQYRSAIYCTTQAQYDAALASRDAYQQQLTAAGYGEITTEIRFPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: YL269_YEAST
Sequence: MKQNLLAVETWYMLILSFRFLFFSRNYNLILCDYLVNTQTVNRVVMAIRSSKRVGKPLFLRYIVMISLKRLPKKCRCGGSPASLPEKYVIMSNKLPYYTNTELDYVIHLDQIDRDL
What are the official names of this protein?
Putative uncharacterized protein YLR269C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VKT5_PSETT
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFCELLPDTGSCEDFTGAFHYSTRDRECIEFIYGGCGGNANNFITKEECESTCAA
What is the function of this protein?
Serine protease inhibitor (By similarity).  Does not inhibit plasmin, and does not reduce blood loss in the mouse tail vein blood loss model.
What are the official names of this protein?
Kunitz-type serine protease inhibitor textilinin-5, Txln-5.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: GALA_BOVIN
Sequence: MPRGSVLLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS
What is the function of this protein?
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3.  This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
What are the official names of this protein?
Galanin peptides.
What is the protein family that this protein belongs to?
Belongs to the galanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CPHA_GEMHP
Sequence: MKILKTQTLRGPNYWSIRRQKLIQMRLDLEDVAEKPSNLIPGFYEGLVKILPSLVEHFCSRDHRGGFLERVQEGTYMGHIVEHIALELQELAGMPVGFGRTRETSTPGIYNVVFEYVYEEAGRYAGRVAVRLCNSIITTGAYGLDELAQDLSDLKDLRANSALGPSTETIIKEAEARQIPWMLLSARAMVQLGYGANQQRIQATLSNKTGILGVELACDKEGTKTTLAEAGIPVPRGTVIYYADELADAIADVGGYPIVLKPLDGNHGRGITIDINSQQEAEEAYDLASAASKTRSVIVERYYKGNDHRVLVINGKLVAVSERIPAHVTGNGSSTIEELIQETNEHPDRGDGHDNVLTRISIDRTSLGVLKRQGFEMDTVLKKGEVAYLRATANLSTGGIAIDRTDEIHPQNIWIAERVAKIIGLDIAGIDVVTPDITKPLTEVDGVIVEVNAAPGFRMHVAPSQGLPRNVAAPVIDMLFPDNHPSRIPILAVTGTNGKTTTTRLLAHIYRQTGKVVGYTSTDGIYLGDYMVEKGDNTGPVSAGVILRDPTVEVAVLECARGGILRSGLAFESCDVGVVLNVAEDHLGLGDIDTIEQMAKVKGVIAESVNADGYAVLNADDPLVAQMAKNVKGKIAYFSMSKDNPIIIDHLRRNGMAAVYENGYLSIFEGEWTLRIEKAENIPVTMKAMAPFMIANALAASLAAFVHGIDIELIRQGVRSFNPGANQTPGRMNLFDMKDFSVLIDYAHNPAGYLAVGSFVKNWKGDRLGVIGGPGDRRDEDLMLLGKIASQIFDHIIIKEDDDNRGRDRGTVADLIAKGIVAENPNASYDDILDETEAIETGLKKVDKGGLVVIFPESVTGSIEMIEKYHLSSE
What is the function of this protein?
Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
What are the official names of this protein?
Cyanophycin synthetase, Cyanophycin synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MurCDEF family.
Protein: SYNPR_HUMAN
Sequence: MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI
What is the function of this protein?
Intrinsic membrane protein of small synaptic vesicles.  Probable vesicular channel protein (By similarity).
What are the official names of this protein?
Synaptoporin.
What is the protein family that this protein belongs to?
Belongs to the synaptophysin/synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: ASR4_SARSH
Sequence: MPASLPGQDGGGTRTTRPRSQLRAACDSCNKSKTKCPGGNPCPLCQCSGIRCHYSVAHQLGRPKGSKNKRTLMREMQGSLGNGDASGQFQPNRIVTTAQAHISSNPSPVGSQSQQQQHPQQAGQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQQHLLPHAFSNTMQNAGTTAAYAGAEKEDSPLAMDDGELFSMLDQTLLMDTMTDEMSDFGQLVPQALPHPMTMPESLTSLLNHDTAFDATQLSNEYSTSSNSKPSTTDDSCMALPTPDSSTTHRPSSSVFGDGHITFSSGTASASRTSASSIVEQQSIPTSPVTVAPMSPAKSSSVPRTLPPATVTPTCTCLPGLVTLICQLEDLRHPPPPRHTSGQHPHQHPASPYSLKCILQGVQLAEEPWAGFARCLDAAGARKRHGAQENTVQDDDGNDHHRHALALYAMSIRIILSSIHKYRIALSMTGQQQRQHNFGDSPEDLDDAASVLVSVGGVQLAGETKSEMIKIAVRLALKQTTAALMRLLECRNRSSSAPSSATMQVAEYSVGHGRFESTAMVRDHPLPHSMSYSSLKTLAGPHTNMITGQDQLEKRENVAGMLSILQYTTKDLIDGANFDWR
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor.
What are the official names of this protein?
Transcription factor asR4, Xenovulene A biosynthesis cluster protein R4.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURA_BURMA
Sequence: MQVTVNEHDAVECVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCAGLLSAEPVRLDNVPDLKDVRTTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQAMGAEIHIEHGYIEARAKRLSGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGATIDEGVDTLRVRMDGRPSAVAIRTSEYPAFPTDMQAQFMALNAVAQGAAQVTETIFENRFMHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRASASLVIAGLCAQGETLVERIYHLDRGYDRMETKLTAVGANVRRISGSEA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP2C_MOUSE
Sequence: MLWKITDNVKYEEDCEDRHDSSSNGNPRIPHLSSPGQHLYSPAPPLSHTGVAEYQPPPYFPPPYQQLAYSQSADHYSHLGEAYAAAMNPLHQPAATGSQQQAWPGRQSQEGSSLASHHSRSASLIPHISGLEGGSVSARREVYRRSDLLLPHAHALEAGLAENLGLHEMAHPIEEVQNVDDAHLLLHDQTVIRKGPISMTKNPLGLPCQKDLVGVVMNPSEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAEFPSKAVADYLTRPHLGGRNEMATRKSMLLAAQQVCKEFTDLLHQDRTPNGNNRPAQVLEPNIQNCLSHFSLITHGFGSQAICAAVSAVQNYIKEALIAIDKSYMNPGDQSPADSSKTMEKMEKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
What are the official names of this protein?
Transcription factor AP-2 gamma, AP2-gamma, AP-2.2, Activating enhancer-binding protein 2 gamma.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_FRATF
Sequence: MVVIRMARGGAKKRSFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DEOC_CLOBB
Sequence: MNNAEILKHVDHTLLKPVATWDDIKKICDESIEYNTASICIPACYISRIHATYGDKVNICTVVGFPLGYSSTEGKIAETKQALADGANEIDMVINISDVKNKAYDKVTEEIRALKEVVGNKILKVIIETCYLTEEEKIAMCKAVTEAGADYIKTSTGFGTGGATLEDIKLFKKHIGPNVKIKAAGGVSTVEDLNMFINEGCDRLGTSRAVGLLKGEETQGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_METFK
Sequence: MTKFVFVTGGVVSSLGKGIAAASLGAILESRGIKVTMLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFISARMGKRNNFTTGQIYETVIKKERRGEYLGKTVQVIPHITDEIKAHVKRGAEGADVAIVEVGGTVGDIESLPFLEAIRQMGIEEGRSNTCFMHLTLLPWIPTAGELKTKPTQHSVKELREIGIQPDILLCRADRAIPEDEKRKIALFTNVPHEAVISVVDADSIYSIPRMLHDQMLDEIVCHKLNLLARAADLSSWNRIVHALKNPKHEVNVAFVGKYVDLTESYKSLTEALIHAGIHNESKVNIHYIDSEEVEKHGTGELEKMDAILVPGGFGKRGTEGKIAAIRYARESKTPYLGICLGMQLAVIEFARNVAGLKDANSTEFDPHTPHPLVGLITEWKNADGKVEQRSEDSDLGGTMRLGAQKCPIVPDTKAFTIYGAEVNERHRHRYEVNNHYVDKLEKAGLVVSARTPTEQLCEMVELPSEVHPWFVACQFHPEFTSNPRTGHPLFNAYIAAALANRKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DNJB3_HUMAN
Sequence: MVDYYEVLDVPRQASSEAIKKAYRKLALKWHPDKNPENKEEAERRFKQVAEAYEVLSDAKKRDIYDRYGEAGAEGGCTGGRPFEDPFEYVFSFRDPADVFREFFGGQDPFSFDLLGNPLENILGGSEELLGKQKQSVCTPFLCLQ
What is the function of this protein?
May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.
What are the official names of this protein?
DnaJ homolog subfamily B member 3.
Protein: CCME_RICTY
Sequence: MQKIVRNRLIKIILCFCSTCLGISIILYNLEKNIIFFFPPSKINEAEQGKELRVGGLVKRDSINRISANKISFVITDNIKDLEILYQGVLPALFREGQGIIAIGQLSDNKFIARQLLAKHDENYRPPS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: VSP09_TRIST
Sequence: MVLIRVLANLLILQLSYAQKSSELVVGGDECNINEHRFLVLVYTDGIQCGGTLINKEWMLTAAHCDGKKMKLQFGLHSKNVPNKDKQTRVPKKKYFFPCSKNFTKWDKDIMLIRLNHPVNNSTHIAPLSLPSKPPSQDTVCNIMGWGTISPTKEIYPDVPHCANINIVDHAVCRAFYPGLLEKSKTLCAGILEGGKDICQGDSGGPLICNGQIQGIVSVGGNPCAEPRVPAIYTKVFDHLDWIKSIIAGNTAATCPL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease KN9, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MALH_FUSMR
Sequence: MKQFSILIAGGGSTFTPGIILMLLDNLDKFPIRQIKMFDNDAERQAKIGEACAILLKEKAPQIKFSYSTNPEEAFTDIDFVMAHIRVGKYPMRELDEKIPLRHGVVGQETCGPGGIAYGMRSIGGVIGLIDYMEKYSPNAWMLNYSNPAAIVAEATRRLRPNSKVLNICDMPIGIEVRMAEILGLESRKDMDIMYYGLNHFGWWKSVRDKQGNDLMPKLREHVSQYGYVVPKGDNQHTEASWNDTFAKAKDVLALDPTTLPNTYLKYYLFPDYVVEHSNKEYTRANEVMDGREKFVFGECEKVVKNQSSEGCALHIDEHASYIVDLARAIAFNTKEKMLLIVENNGAIVNFDSTAMVEIPCIVGSNGPEPLVVGRIPQFQKGMMEQQVTVEKLTVEAWIEGSYQKLWQAITMSKTVPSAKVAKDILDDLIEANKEYWPVLK
What is the function of this protein?
Hydrolyzes a wide variety of 6-phospho-alpha-D-glucosides including maltose-6'P, trehalose-6P and the 6'-phosphorylated derivatives of the five linkage-isomeric alpha-D-glucosyl-D-fructoses: trehalulose-6'P, turanose-6'P, maltulose-6'P, leucrose-6'P, and palatinose-6'P.  However, sucrose-6P is not a substrate for MalH, and this enzyme also fails to hydrolyze beta-O-linked phosphorylated disaccharides such as cellobiose-6'P and gentobiose-6'P.
What are the official names of this protein?
Maltose-6'-phosphate glucosidase, 6-phospho-alpha-D-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: LART1_LEGPH
Sequence: MYSKYPAFFLNKNIKSSSGVQFSNVVKIPSAIESLYRGDNNLTGIIFLLPTLITGVFCQNFPEVVDIEQIRLHKLTNLSNDFHMVSMSEDPQIALDWGNGCFITIDPVSFSDYIVDVHATFSENQLNLPGRMEREKEHVALAVPFCSIKKITIHNKELANPFYLSIPQENHEAKMELNTLYGELISLLRKKYTQEVDEKEEQIALRTYAIRYLDFYAKFCGCDNPFDKTIAQLSELYPEFMSNFLQSSHFSSKTGLMKEIVVNSLDNLFKEHPYTKSIDASYIYRVKESTTCYEDDWAKPVYD
What is the function of this protein?
ADP-ribosyltransferase that targets a specific class of NAD(+)-dependent glutamate dehydrogenase (GDH) enzymes found in fungi and protists, including many natural hosts of Legionella.  Acts by targeting a conserved arginine residue in the NAD(+)-binding pocket of GDH, thereby blocking oxidative deamination of glutamate.  Lart1 may target amoeba GDH to prevent a conserved stress response.  In vitro, acts on Glud2 from the amoeba Dictyostelium discoideum (DdGluD2) and yeast Gdh2p but does not act on human or Legionella GDH homologs.
What are the official names of this protein?
NAD(+)--arginine ADP-ribosyltransferase Lart1, Legionella ADP-ribosyltransferase 1, Legionella ART 1, Mono-ADP-ribosyltransferase, Mono-ART, mART.
What are the subcellular locations of this protein?
Secreted. Note=Translocated into the host cell via the type IV secretion system (T4SS).
Protein: EDS1_YEAS6
Sequence: MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEKGTKQRKKASRACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRASVVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQFVKVPYDDIKRRSSLATLGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEEMGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQCMLTPNSVRSIEKERLNSLTAGCPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTEKNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDPEKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYYIQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLLLGPSVGVFNEFQAHKLFLPFENTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDTLQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFVLNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQKNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYFAQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIPTTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVSATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCCCCFFN
What are the official names of this protein?
Transcriptional regulatory protein EDS1, Expression dependent on SLT2 protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1_ENT38
Sequence: MAKEDNIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRE1B_ARATH
Sequence: MRGSALLDLILFLLVSPLAHSFKGSEISKFYDKSISNQISQSDRESGYVLVSTVDGSISLVDMSSQKLDWTFHTNEPIYSSYQAPHYHYTTDEERSSVLGDDFYMDCDKDWRLYNSSVRKGKRVNEIVDASEFIGTLPYTSTDRIVLGKKDTSVFLLDWKTGKLVKRYRMDELYSNTVVENDKEKAIVLSKEAPLLFGSGFKKSEDFPELVYIERKDFKIQCISKFGDVLWSVSYAKMEAKLQNHESVQFISGLSSSVGKNQFPLSYTTSVPMVQLRNVKYETLFPRLGFLDEALYLPFQDRKPNQLAIGDGNQLTLPGNKEAEEVLSLPLPETVISQITDIIDGSTKQAGFASKFSGLIVLIFGFCVTMLSVCGLFFYRLRQSIRIKEPYVSEVPIATPKKKKSKKNGTTKAVHKKENGFISGGNKDPSHEENEKRLLTAFPGLNNSSAEGYRVGKLFVSNKEIAKGSNGTVVLEGSYEGRLVAVKRLVQSHHDVAQKEILNLMASDKHSNIVRWYGVDQDEHFIYISLELCACSLNDLIYASSALLESPMASSSIHSIQINPIFENGKGVELWKENGHPSPVLLKLMRDIVAGLVHLHDIGIVHRDLKPQNVLIVKNSSLCAKLSDMGISKRLPADTSALTRNSTGLGSGSSGWQAPEQLRNERQTRAVDLFSLGCVLFFCMTGGKHPYGDNYERDVNVLNDQKDLFLIESLPEAVHLLTGLLNPDPNLRPRAQDVMHHPLFWNSDMRLSFLRDASDRVELENREEGSQLLAALESTAAVTLNGRWDEKLDSIFLDNIGRYRRYKFDSIRDLLRVIRNKLNHYRELPKELQELLGSVPEGFERYFSSRFPKLLIQVYTVLFDYCNNEEFFFKYSKTTVF
What is the function of this protein?
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation.  The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes.  Involved in organ growth regulation.  Plays a role in plant immunity and abiotic stress responses.  Required for ER stress-induced autophagy.
What are the official names of this protein?
Serine/threonine-protein kinase/endoribonuclease IRE1b, Endoplasmic reticulum-to-nucleus signaling 1-1, Inositol-requiring protein 1-1, AtIRE1-1, Serine/threonine-protein kinase/endoribonuclease IRE1-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ADF4_ARATH
Sequence: MANAASGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVIVEKVGEPILTYEDFAASLPADECRYAIYDFDFVTAENCQKSKIFFIAWCPDVAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVLKSRVN
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (PubMed:19346440, PubMed:22010035).  Contributes to the stochastic dynamic turnover of actin filaments (PubMed:22010035).  Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin.  Involved in resistance triggered by the effector AvrPphB of Pseudomonas syringae pv tomato (Pst).  May modulate the AvrPphB-RPS5-mediated defense signal transduction pathway (PubMed:19346440).  During AvrPphB-triggered resistance signaling pathway, involved in the control of MPK3 and MPK6 activation, via the coordinated regulation of actin cytoskeletal dynamics and RPS5 resistance gene transcription (PubMed:23144618).  During innate immune response triggered by the bacterial elf26 peptide, the inhibition of ADF4 regulates actin dynamics in order to execute key events associated with pattern-triggered immunity (PTI), such as cell wall fortification and transcriptional activation of defense gene markers (PubMed:24464292).
What are the official names of this protein?
Actin-depolymerizing factor 4, ADF-4, AtADF4.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: Y467_TREPA
Sequence: MNSYFSALPLKCVRRPFILSRNEGWGIKRFYVADEPHRSFLCMQEGVRRGGGESEITQRKADVLRKSIRSADRYKEDRSCRT
What are the official names of this protein?
Uncharacterized protein TP_0467.
Protein: TACC2_MOUSE
Sequence: MGNENSTSDHQRTSSVQSPRSLQPPGKSQSLQKQQGDLPGSCAGSIPGTDDVIQPAAPVDPGHPPLAGIGSNQGEVCTSLQLSYTIVTVQSASPSAARASPAPLAPEHTASAPSAAGPGVEVTPTGSPQHLAKNEPRSSDSEEAFETPESTTPVKAPPAPPPPPPEVTPEPEVIDPPAPEEPGCISEPPVVVPDGPRSSESVEGSPFRPSHSSSAVFDEDKPIASSGTYNLDFDSIELVDNFQSLEPCSADSKGQECKVSTRRKSTESVPPSKSTLSRSLSLQASDFDGASCPGSPEAGTLTTDACGTGSNSASSTLKRTKKTRPPSLKKKQATKKPTETPPVKETQQEPGEESPVPSEEHLAPETKTESATPEGAGCTLSDDTPLESPAVPTATCPLTLESAEDVSPLVSGGGRVQNSPPVGRKSVPLTTASEAVEVTLSDSGGQEDLPAKGLSVRLEFDYSEDKGSWESQQENAPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPTEPSDTPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLSQQSYNFDPDACEESLDPFKASSKTPSSPSKSPASFEIPASTTEADGDGLNKPAKKKKTPLKTMVEDVMSVCSLFDTFRVKKSPKRSPLSDPPSQDPTPAATPEAPSAISTVVHATDEEKLAVTSQKWTCMTVDLDADKQDFPQPSDLSNFVNETKFNSPSEELDYRNSYEIEYMEKLGSSLPQDDDTPKKQALYLMFDTPQESPVKSPPVRMSDSPTPCSGSSFEDTEALVNAATKLQHPVARGLPSSQEPLLQVPEKPSQKELEAMALGTPAEAIEITAPEGAFASADTLLSRLAHPASLCGALGYLEPDLAEKNPPVFAQKLQEELEFAVMRIEALKLARQIALASRSRQDTKREAAHPPDVSISKTALYSRIGSTEVEKPPGLLFQQPDLDSALQVARAEVIAKEREVSEWRDKYEESRREVVEMRKIVAEYEKTIAQMIPGTERKILSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKKCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAYQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
What is the function of this protein?
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome.  Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors.  May play a role in organizing centrosomal microtubules (By similarity).
What are the official names of this protein?
Transforming acidic coiled-coil-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TACC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SYR_MYCVP
Sequence: MTPADLAELLKATAAAVLAEHGLDSAALPAIVTVERPRNPEHGDYATNLALQLGKKVGANPRELAGWLAAALVAKDGIAAADVAGPGFVNLRIEASAQNVIVGDVIAAGATYGASGELDGRRVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAEVVREYYFNDHGAQIDRFTNSLIAAAKGEPAPEDGYAGTYIADIAAQVLAKEPGALELPDAEMRETFRAVGVNLMFDHIKESLHEFGTDFDVYTHEDSMHTSGRVDQAIAKLRETGSIYEKDGAVWLRTTDFGDDKDRVVIKSDGQPAYIAGDLAYFLDKRKRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYALIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELGVAADTAHLDLLTHDKEGTLIRNIGEFPRVLKTAASLREPHRVSRYLEDLAGDYHRFYDSCRVLPQGDETPGDLHAARLALCAATRQVIANGLGILGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y088_METS3
Sequence: MEFQHIDLNQTHIRLTTDLKNNNLEKYILNLRKELEHYITKNKDFQLSLEPVNHDEEDLSEIIKRMYTASSYCDVGPMACVAGCISEMSLDYLISKKSEYSIIENGGDIAIVNNKKAVCGIYSNNPILGNKIGFELKARKTPLGICTSSGKIGHSISFGYADSVTVLSKKASVADGLATKIANEAVGQNSEYKVSNALEASENYKDLFEGVLIISQDNVGSIGKLPKIVETEEFNVKM
What are the official names of this protein?
UPF0280 protein Msm_0088.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: ACKA_MICAN
Sequence: MKILVLNAGSSSQKSCLYDLEFLPGHPPQPIWQAGIDWTVNPDYAVLTVKAQGIKQEINLSSQDRPAGIARMLDTLVTGETKVVANLADISIVGHRVVHGGTEYSQATMITPQVKETIKKLIPLAPSHNPAHLEGIEAIEQVLGDVPQVAVFDTAFHRSIPPESSLYPIPYQWSELGIRRYGFHGTSHQYCSQRAAELLGKPLESLKMVICHLGNGASLSAVKGGKSIDTTMGFTPLEGLMMGTRSGSIDPGILIYLEREYQYNPDSLNSLLNKESGLKGISGISGDMRAITTAMAEGNERAKLAFEMYIHRLKSLIGSMIASLEGLDVLVFTAGIGENSALVREKASQGWSFFGLELDLAKNAARPRDEDIASETSKVRVMVIATAEDWAIARECWHLSP
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.