PharMolix/UniProtQA huggingface dataset:
Protein: PANC_ECOSM
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIIAIAGQELNEKGFRSDDIQIRDADTLLEISENSKRAVILVAAWLGDARLIDNKIVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN488_HUMAN
Sequence: MPEWPPCLSVAPALVITMAAGKGAPLSPSAENRWRLSEPELGRGCKPVLLEKTNRLGPEAAVGRAGRDVGSAELALLVAPGKPRPGKPLPPKTRGEQRQSAFTELPRMKDRQVDAQAQEREHDDPTGQPGAPQLTQNIPRGPAGSKVFSVWPSGARSEQRSAFSKPTKRPAERPELTSVFPAGESADALGELSGLLNTTDLACWGRLSTPKLLVGDLWNLQALPQNAPLCSTFLGAPTLWLEHTQAQVPPPSSSSTTSWALLPPTLTSLGLSTQNWCAKCNLSFRLTSDLVFHMRSHHKKEHAGPDPHSQKRREEALACPVCQEHFRERHHLSRHMTSHS
What is the function of this protein?
Transcriptional repressor.  Plays a role in oligodendrocyte differentiation, together with OLIG2.  Mediates Notch signaling-activated formation of oligodendrocyte precursors.  Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury.
What are the official names of this protein?
Zinc finger protein 488.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UGGG_DROME
Sequence: MLRAVALCVSVVLIALYTPTSGESSQSYPITTLINAKWTQTPLYLEIAEYLADEQAGLFWDYVSGVTKLDTVLNEYDTESQQYNAALELVKSHVSSPQLPLLRLVVSMHSLTPRIQTHFQLAEELRSSGSCQSFTFAQVGSELACSFNELQKKLEVPLAKDSLDASVVTYSFDHIFPGSENNTRTVVLYGDLGSSQFRTYHKLLEKEANAGRIRYILRHQLAKKDKRPVRLSGYGVELHLKSTEYKSQDDAPKPEAGSTSDEDLANESDVQGFDFKVLKQKHPTLKRALDQLRQRLLQGNDEIAQLKAWEFQDLGLQAAAAIAEIQGDETLQILQYTAHNFPMLARTLLAHKVTDGLRAEVKHNTEAFGRSLNVAPPDGALFINGLFFDADTMDLYSLIETLRSEMRVLESLHSNNVRGSLASSLLALDLTASSKKEFAIDIRDTAVQWVNDIENDVQYRRWPSSVMDLLRPTFPGMLRNIRKNVFNLVLVVDALQPTARSVIKLSESFVIHQAPIRLGLVFDARDANEDNLADYVAITCAYNYVSQKKDARAALSFLTDIYAAVGETKVVTKKDIVKQLTKEFTSLSFAKAEEFLEEDSTYDYGRELAAEFIQRLGFGDKGQPQALLNGVPMPSNVVTADSDFEEAIFTEIMTHTSNLQKAVYKGELTDNDVAIDYLMNQPHVMPRLNQRILSQEDVKYLDINGVAYKNLGNVGVLNRLSNRDMTATLMDNLKYFGGKKSTELIGRASLQFLTIWVFADLETDQGRDLLTHALDYVQSGESVRVAFIPNTESSSASSRRNLNRLVWAAMQSLPPTQATEQVLKWLKKPKEKIEIPTQLEDILGSTELHLKMLRVYSQRVLGLNKSQRLVIGNGRLYGPLSSDESFDSADFALLARFSSLQYSDKVRQVLKESAQDVNEEFNSDTLLKLYASLLPRQTKTRFKLPTDLKTDHSVVKLPPKQENLPHFDVAAVLDPASRAAQKLTPILILLRQVLNCQLNLYLIPVPQHSDMPVKNFYRYVVEPEVQFEANGGRSDGPLAKFSGLPANPLLTQQLQVPENWLVEAVRAVYDLDNIKLTDIGGPVHSEFDLEYLLLEGHCFDAASGAPPRGLQLVLGTQSQPTLVDTIVMANLGYFQLKANPGAWSLRLREGKSADIYAISHIEGTNTHHSAGSSEVQVLITSLRSHVVKLRVSKKPGMQQAELLSDDNEQAAQSGMWNSIASSFGGGSANQAATDEDTETINIFSVASGHLYERLLRIMMVSLLKHTKSPVKFWFLKNYLSPQFTDFLPHMASEYNFQYELVQYKWPRWLHQQTEKQRTIWGYKILFLDVLFPLNVRKIIFVDADAIVRTDIKELYDMDLGGAPYAYTPFCDSRKEMEGFRFWKQGYWRSHLMGRRYHISALYVVDLKRFRKIAAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIHQVAIKSLPDDWLWCQTWCSDSNFKTAKVIDLCNNPQTKEAKLTAAQRIVPEWKDYDAELKTLMSRIEDHENSHSRDSAVDDSVDDSVEVTTVTPSHEPKHGEL
What is the function of this protein?
Recognizes glycoproteins with minor folding defects (PubMed:22960071).  Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum (PubMed:22960071).  Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation (PubMed:11535823).
What are the official names of this protein?
UDP-glucose:glycoprotein glucosyltransferase, UGT, dUGT, UDP--Glc:glycoprotein glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
Protein: FABZ_NITEC
Sequence: MDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGVLIVEALAQAAALLTIRSENMEKDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKGIWKYSACAEVDGQLVTEAQLMCTARAI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_CAUSK
Sequence: MILYPAIDLKDGQCVRLLHGDMEKATVFNNSPADQAERFVRDGFSWLHVVDLNGAIEGKSVNTAAVQSILESISIPVQLGGGIRTLEGVEAWIEAGVSRVILGTVAVHDPDLVRKAARLWPEQIAVAVDVRDGKVAVDGWTGLSDLDAITLGKRFEDVGVAALIVTDISRDGALTGVNVEGVGELADAVSIPVIASGGVASVADIERLKARPGVEIAGAILGRSLYAGTIRPAEALTIAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_VIBPA
Sequence: MKIKALSKLKPEQGIWMTEVDKPEVGHNDILIKIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQEVRGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNREGAFAEYLVIPAFNAFKIPDEISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAEEKLEDVMAELGMTEGFDVGLEMSGNPAAFNSMLTTMNHGGRIALLGIPPSDMGIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDLSPIITHHYKIDDFQEGFDVMRSGMSGKVILDWE
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_TUPVT
Sequence: MSLSRLYSKKTQSSYNATAPLDRDPPEYPGDAFKKSRNKPTLTRPKSNLSLDDARCMIKGQIQNGSVDIELAKHYLILVLEQITEDNSDDWTSFGVQILSRTERGRPLCMVNIQLDDKDKTFDSQVKDSTATVEDDLWMTTYLLAIYRIGRATNKNYQTQLIDELNKLLATFPGDYVPMVQALQAFDSWPNDPNYCKLVACVDMFFSRFKKSKWAILRFGTISSRYRDCAALTALNHFSRLLGVDLVDALEWSFVGRVSDEIEQMLKPDQELDKVDSYTPYMIDLGISKASPYSTVRNPAWHLFCHTVGSLMMSRRSINARHLEAPDQSNILSNAELIVFVFETRIKWLKNFRKLDSVDASDQLDQVAPVVLGTKDLPNTTNADDWFSWMKLNNFELPDECGRYVSKLAKKLKDSREGSVGQFVYLRLGD
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Nucleocapsid assembly is concommitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0).  All replicative products are resistant to nucleases.
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=The nucleocapsid is synthesized in the cytoplasm, and is subsequently transported via microtubules to the cell periphery.
Protein: LECC_PHYAM
Sequence: MKRSNSIAVMLVLVLSSLMLLLPVEGQGHEGHGVGEILLMGKLGAPVCGVRASGRVCPDGYCCSQWGYCGTTEEYCGKGCQSQCDYNRCGKEFGGKECHDELCCSQYGWCGNSDGHCGEGCQSQCSYWRCGKDFGGRLCTEDMCCSQYGWCGLTDDHCEDGCQSQCDLPTLLPSPLRRIIAIRKLKANLANMLS
What is the function of this protein?
N-acetyl-D-glucosamine binding lectin.  Almost no hemagglutinating activity towards human erythrocytes.  Low mitogenic activity towards human peripheral blood lymphocytes.
What are the official names of this protein?
Lectin-C, PL-C.
Protein: RL7_VIBCH
Sequence: MSITNEQILDAIAEMSVMQVVELISAMEEKFGVSAAAAVVSGPAAAAAVEEQTEFNVILAAAGANKVAVIKAVRGATGLGLKEAKALVDGAPASVKEAVSKEEAEALKKELEEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UBIE_CELJU
Sequence: MSEKKTTHFGFQQVPVEEKAQRVAEVFHSVAAKYDLMNDLMSGGIHRLWKRFTIEASGVRTGHKVLDIAGGTGDLSYQFARLVGSSGQVILADINASMLGVGRDRLIDRGIAGNIAFTQCDAQYLPFPDNTFDCITIAFGLRNVTDKDLALRAMQRVLKPGGRLLVLEFSKPHNELLSKAYDTYSFRILPFMGKLVTNDADSYRYLAESIRMHPDQQTLKGMMDDAGFVNTEFHNMTGGIVALHKGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RS21_XYLFA
Sequence: MPSVKVRENEPFEFALRRFKRICEKAGILAETRKREFYEKPTQERKRKAAAAVKRQMRRTSRDVTKRKRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL24_CAMC5
Sequence: MANVKFQVKKGDLVKIIAGDDKGKTGKILSVLAKKSQVIVEGCKVAKKAIKPSEKIPNGGHINKEMPIHISNVAKVEE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL31_BIFLS
Sequence: MQQGIHPDYHPVEVTCSCGNTFVTRTAGKEDHMFVDVCSQCHPFYTGKQKILDTGGRVARFEKRYGKKSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL36_HELPJ
Sequence: MKVRPSVKKMCDKCKIIKRRGVIRVICATPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y240_ATV
Sequence: MGEGKGENKWGAAQMSNNPIRNKDFKVFGLVEKIYEQKGEFVKLFAEIKKKLYSMSIEQLLLMPSYARSKLKDEYGHIEFEYAGYGDRIVIVKLEDPWTDDTNKRQGKTAFLVYFSYQTSKPLVPAQITYKIRSIFKTMKELNQKGYRVFPALFANSITPGALKILQNPKINIRFFSDVNDLLNWIYSKVLNRLKKIVEIAKFTLKFDKIFTFLKTIIAGLGYEVPSDILMAWASKPVRP
What are the official names of this protein?
Uncharacterized protein ORF240.
Protein: PCYOX_MACFA
Sequence: MGRAVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAVIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSTVQASGGLLGIYNGEALVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVDYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKHTGNPTKMYEVVYQIGTETHSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLSTVLTTDNSDLFINSIGIVSSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL
What is the function of this protein?
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity).  Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).  Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (By similarity).
What are the official names of this protein?
Prenylcysteine oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the prenylcysteine oxidase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: EDR1_ARATH
Sequence: MKHIFKKLHRGGNQEQQNRTNDAAPPSDQNRIHVSANPPQATPSSVTETLPVAGATSSMASPAPTAASNRADYMSSEEEYQVQLALAISASNSQSSEDPEKHQIRAATLLSLGSHQRMDSRRDSSEVVAQRLSRQYWEYGVLDYEEKVVDSFYDVYSLSTDSAKQGEMPSLEDLESNHGTPGFEAVVVNRPIDSSLHELLEIAECIALGCSTTSVSVLVQRLAELVTEHMGGSAEDSSIVLARWTEKSSEFKAALNTCVFPIGFVKIGISRHRALLFKVLADSVRLPCRLVKGSHYTGNEDDAVNTIRLEDEREYLVDLMTDPGTLIPADFASASNNTVEPCNSNGNKFPTAQFSNDVPKLSEGEGSSHSSMANYSSSLDRRTEAERTDSSYPKVGPLRNIDYSSPSSVTSSTQLENNSSTAIGKGSRGAIIECSRTNMNIVPYNQNSEEDPKNLFADLNPFQNKGADKLYMPTKSGLNNVDDFHQQKNNPLVGRSPAPMMWKNYSCNEAPKRKENSYIENLLPKLHRDPRYGNTQSSYATSSSNGAISSNVHGRDNVTFVSPVAVPSSFTSTENQFRPSIVEDMNRNTNNELDLQPHTAAVVHGQQNDESHIHDHRKYTSDDISTGCDPRLKDHESTSSSLDSTSYRNDPQVLDDADVGECEIPWNDLVIAERIGLGSYGEVYHADWHGTEVAVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGAVTRPPNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPTIVHRDLKTPNLLVDNNWNVKVGDFGLSRLKHNTFLSSKSTAGTPEWMAPEVLRNEPSNEKCDVYSFGVILWELATLRLPWRGMNPMQVVGAVGFQNRRLEIPKELDPVVGRIILECWQTDPNLRPSFAQLTEVLKPLNRLVLPTPQ
What is the function of this protein?
MAPKKK serine/threonine-protein kinase involved in the regulation of a MAP kinase cascade (probably including MPK3 and MPK6) that negatively regulates salicylic acid- (SA-) dependent defense responses, abscisic acid (ABA) signaling, and ethylene-induced senescence.  Modulates also stress response (e. g.  drought) signaling and cell death, in an ORE9-dependent manner.  Functions at a point of cross talk between ethylene, ABA and SA signaling that impinges on senescence and cell death.  On the other hand, it confers sensitivity to various pathogens such as the fungus E. cichoracearum, the oomycete H. parasitica and the bacteria P. syringae pv.  tomato DC3000.  Required for resistance to some hemibiotrophic/necrotrophic fungal pathogens (e. g.  C. gloeosporioides, C. higginsianum and A. brassicicola) through the induction of defensin expression, probably by repressing MYC2, an inhibitor of defensin genes (PDFs).  Together with KEG, may regulate endocytic trafficking and/or the formation of signaling complexes on trans-Golgi network (TGN)/ early endosome (EE) vesicles during stress responses.
What are the official names of this protein?
Serine/threonine-protein kinase EDR1, MAPKK kinase EDR1, Protein ENHANCED DISEASE RESISTANCE 1, AtEDR1, Serine/threonine/tyrosine-protein kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
What are the subcellular locations of this protein?
Cell membrane. Endosome. Nucleus. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Early endosome. Note=Displays dynamic movement in cells with accumulation at the plasma membrane around pathogenic fungus penetration site (PubMed:25747881). Excluded from the nucleolus. Targeted to trans-Golgi network and early endosome vesicles via interaction with KEG.
Protein: MTNB_COCP7
Sequence: MTDPENNDQLVKSSDPEHPANLIPELCKKFYTLGWVTGTGGGTSIRRGDHIFIAPSGVQKEMIKSEDIFVLSYPTPKYPPSARQYIRKPRELKPSACTPLFLAAFDRGAGCSIHTHSQWAVLVTLLVEREKGKNGCFEINNIEQIKGIPKGKGKGMLGYFDTLRIPIIENTAFEEDLTESLEQAMDEYPDTYAVLVRRHGIYVWGDTPAKAKTQCESLDYLFQLAVEMHKLGIPWIQ
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB1_SUIBO
Sequence: MREIVHIQTGQCGNQIGAKFWEVVSDEHGIERDGLYKGTNDMQLERISVYYNEIGSNKYVPRAVLVDLEPGTMDSVRSGPLGGLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAEGTDCLQGFQITHSLGGGTGAGMGTLLMSKIREEYPDRMMCTYSVVPSPAVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICFRTLKLSTPTYGDLNHLVSFVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMTGFAPLTARGSQQYRAVTVPELTQQMFDAKNMMAASDPRHGRYLTVAAVFRGKVSMKEVEEQMQNVQNKNSAYFVEWIPNNVLSAQCDIPPRGVKMAVTFLGNSTAIQELFKRVSDHFTAMFKRKAFLHWYTQEGMDEMEFTEAESNMQDLIAEYQQYQDATVEEEAEYEEEVPADEES
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AK_MYCTU
Sequence: MALVVQKYGGSSVADAERIRRVAERIVATKKQGNDVVVVVSAMGDTTDDLLDLAQQVCPAPPPRELDMLLTAGERISNALVAMAIESLGAHARSFTGSQAGVITTGTHGNAKIIDVTPGRLQTALEEGRVVLVAGFQGVSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPMEDPILTGVAHDRSEAKVTIVGLPDIPGYAAKVFRAVADADVNIDMVLQNVSKVEDGKTDITFTCSRDVGPAAVEKLDSLRNEIGFSQLLYDDHIGKVSLIGAGMRSHPGVTATFCEALAAVGVNIELISTSEIRISVLCRDTELDKAVVALHEAFGLGGDEEATVYAGTGR
What is the function of this protein?
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
What are the official names of this protein?
Aspartokinase, Aspartate kinase, ASK.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: CAS2A_SACS2
Sequence: MAMLYLIFYDITDDNLRNRVAEFLKKKGLDRIQYSVFMGDLNSSRLKDVEAGLKIIGNRKKLQEDERFFILIVPITENQFRERIVIGYSGSEREEKSNVVW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).  Functions as a ssRNA-specific endoribonuclease, producing a 5'-phosphomonoester and a 3'-hydroxy.  Does not process pre-crRNA in the manner expected if it were the CRISPR-processing endoribonuclease.  Prefers U-rich substrates and often cuts between adjacent U residues in regions predicted to be single-stranded.  RNAs as short as 10 residues can serve as substrate.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 1, CAS2 endoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: TPIS_SHEFN
Sequence: MALRRPMVAGNWKMNGNSALAEELFKKFATKLQNDSAEVVLCPPSIYLESVRQLLEANKQTLDGALVRMGAQNLSQHDFGAYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKYGLTPILCVGESGPAREARRTFEVIAEELDIVIEKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRSRLSEVSPFIGENIRILYGGSVTPSNAADIFAQPDVDGGLIGGASLNSSEFLSLCTIAMSA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRL7L_ORYSJ
Sequence: MALQSCCSSSASVPATCSALCLAEATRAASLFVRPRAAARRLVLARCARGREGGESKAVQLVLGGRARDDGSESESSDDEDDDEPMQMTDEQRRTLRRKIREMMDRVPETAEITDPAERKAKMLELLTKYQLVVEEEDPNWPEDDEDGHGFSLGQFFDKITIKAEKKNDDDEEDDAKGNQSDKEIVWEDDNYIKPIRDVKTMDWDDTVFTDFGPLIVLVHNRYKRPQDNENARDQLVKAIEMFWEYNLPSPRCVAVDACAEPDLVKALNVSGFPEVLFTNAGKIVHRDKVVRSAEEWTRMMAFFYYKAARPPCLSEADGQGQEKVPLMS
What is the function of this protein?
Plays an essential role in early steps of chloroplast development.  Involved in the regulation of plastid gene expression.  Required for the proper function of the plastid transcriptional machinery and protein accumulation in thylakoid membranes.  May function as molecular chaperone to ensure proper organization of the nucleoids in chloroplasts.
What are the official names of this protein?
Thioredoxin-like fold domain-containing protein MRL7L homolog, chloroplastic, OsMRL7-L.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PNP_BRUO2
Sequence: MFNTHKVEIEWGGRPLTIETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAKEHFFPEGVEETEMLAEQFATIFTHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_DROME
Sequence: MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANSGSL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_HELPH
Sequence: MLHKKYRPNVAAIIMSPDYPNTCEVFIAERIDIEGAWQFPQGGIDEGETPLEALHRELLEEIGTNEIEILAQYPRWIAYDFPSNMEHKFYAFDGQKQRYFLVRLKHANNIDLNKHTPEFRAYQFIHLKDLLKKIVPFKRQVYRQVIAYFKREGYL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.