PharMolix/UniProtQA huggingface dataset:
Protein: ANXA2_SHEEP
Sequence: MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKKKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity.  May be involved in heat-stress response.  Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
What are the official names of this protein?
Annexin A2, Annexin-2.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In the lamina beneath the plasma membrane.
Protein: VATD_SULIN
Sequence: MSQKVLPTKINLIQFRRQLRLITVIKRLLENKREVLLLYLRTYASEYEKIYNEVNEEMKKVYESYLQAVASEGISNIEEIALSQKPSLEVSSSIKVIFGVKVPTIKLDKSTIPSKPFSDVETSPYLSESYEEMTEAFNKIIELVELESTIRSLVSELRKTQRLINSIDNYILPFYRGSIKFIKQILEDRQREEFSRLKIIRRILQRRRESGSG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: SAP2_ARATH
Sequence: MDHDKTGCQSPPEGPKLCTNNCGFFGSAATMNMCSKCHKDMLFQQEQGAKFASAVSGTSSSSNIIKETFTAALVDIETKSVEPMTVSVQPSSVQVVAEVVAPEEAAKPKGPSRCTTCNKRVGLTGFKCRCGSLFCGTHRYADVHDCSFNYHAAAQEAIAKANPVVKAEKLDKI
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 2, AtSAP2.
Protein: PILS3_ARATH
Sequence: MVKLLELFITSSKPVVEILLITSVGFYMALDGVNLLGHDARKYLNNIVFYVFSPSLIGSRLADSVTYESLVKMWFMPVNVLLTFIIGSLLGWIVIVITKPPSHLRGLILGCCAAGNLGNMPLIIIPAVCKEKGGPFGDPESCQKYGMGYVALSMAMGSIYIWTYVYNLMRVLSNSPVETPPSVESNYDSYKVPLISSKEEENNQKAGRWEKVKRRLVSLSQKVNLKTIFAPSTIAAMIALVIGLITPLRKLIIGTEAPLRVLQDSVTLVGDGAVPAMTMIIGGNLLKGLRSSGMKMSSIIGVLVARYVLLPMSGVLIVRGAYKLDLVTSEPLYQFVLLLQYAVPPAMNLGTITQLFGTGESECSVIMLWTYSLASIALTVWPTFFMWLVA
What is the function of this protein?
Involved in cellular auxin homeostasis by regulating auxin metabolism.  Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
What are the official names of this protein?
Protein PIN-LIKES 3, Auxin efflux carrier-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS18_YERPA
Sequence: MARYFRRRKFCRFTAEGVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARCIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LEPA_SHESR
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQVCGGLSDREMDAQVLDSMDLERERGITIKAQSVTLEYKAKNGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALDMNLDVVPILNKIDLPQADPERVAAEIEDIVGIDAMNAVRCSAKTGVGIDEVLEVIVEQIPPPEGDPEAPLQALIIDSWFDSYLGVVSLVRIKNGVLKKGDKFKVMSTGQNHTADRVGIFTPKQTDKTELKTGEVGFVIAGIKEIHGAPVGDTLTLAKHGAEKPLPGFKKVKPQVYAGVFPISTDEYENFRDALNKLSLNDASLFFEPESSSALGFGFRIGYLGLLHMEIIQERLEREYDLDLITTAPTVVYEVLLTSGETVYVDNPADLPAINNIEEMREPIVEANILVPKEYLGNVITLCIEKRGTQVNMVYHGNQVAVTYHLPMAEVVMDFFDRLKSTSRGYASLEYNFIRFDPADMVRLDILINGDRVDALAMIIHRSNIRHRGLALVEKMKELIPRQMFDIAIQAAVGSQIIARSTVKALRKDVTAKCYGGDVSRKKKLLNKQKEGKKRMKQVGNVEVPQEAFLAVLKLNE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y429_ALIB4
Sequence: MFDGLDLKNLNLGDMLNQFQDMAKNAQNENASRIFTSKAGGGMVEISINGNSEVVDLKIDDSLLEDKDSLQILLISCMNDVIKQSDENKKMMAMNLMGGLGSFGQK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Abu_0429.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL29_CAMLR
Sequence: MKYTEIKDKTAGELATMLKEKKVLLFTLRQKLKTMQLTNPKEISEVKKDIARINTAISALK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CFA20_RAT
Sequence: MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYDPCKLSYPKGLLLRQTLLRG
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (By similarity).  Involved in the regulation of the size and morphology of cilia.  Required for axonemal microtubules polyglutamylation (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 20, Gene trap locus 3 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CFAP20 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: GLUD_CORGL
Sequence: MLSGNGQLDANKWTPFINSQTWTTYILPGLWGTLKSAVFSVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPVLILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIAEILRSGIASLPKGQKEAAIALGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRNYLAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVDWQDPDYKDLKTPGVQ
What is the function of this protein?
Part of the ABC transporter complex GluABCD involved in glutamate uptake.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutamate transport system permease protein GluD, Glutamate uptake system protein GluD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM3_KLEP3
Sequence: MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLNVELVPMVTRGDVILDTPLAKVGGKGLFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNHYASIDELPAGSVVGTSSLRRQCQLAATRPDLVIRSLRGNVGTRLSKLDNGEYDAIILAAAGLKRLKLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTQALLAPLNHAETAVRVRAERAMNTRLEGGCQVPIGSYAELVNGELWLRALVGAPDGSQMVRGERRGPAEQAEALGISLAEELLDNGARDILAAVYDGEAPR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: COFG_META3
Sequence: MVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNNKKYITYSKNVFIPICNWCKNICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFGETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLPHTNCGILSYEELKTLKEVNASMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIVQSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQVPPNLNSETGQLFLFAGVDDWGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLPVYEKYINENWLSCKVLEKIK
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: FUMC_PARMW
Sequence: MGQPMRQEHDSIGGVDVPAAALWGAQTQRSLNNFAIGHQKIPAELIHALARIKQCCAAVNGRHGLLNDQQVALIERAGQAIQTGQQDDHFPLSVWQTGSGTQTNMNVNEVISNLAAQESGENLGSHRPLHPNDHINRSQSTNDVFPAAIHVAAALQLQQELLPELKRLIASLDAKAVAWQDIIKIGRTHLQDAVPLRLGDEVSAWRDRLSDGAHWLTTAHQDLLALPLGGTAVGSGLNTPDRFAHEVCAELASRTGSDFQPADNLFAVMAGHDSLVQTMAQLRRLAVTLLTIANDIRLLACGPRAGLGELLLPANEPGSSIMPGKVNPTQCEAMAMVCTQVIGMDAAVAAAGAGGHLQMNVYKPLIGYNLIEGIRLLQDACRCFRLNLLTGMEADRDRIAFYVERSLMLVTALTPEIGYEKACAIAQHAHRDGLTLREAAMQSGAITDERFDQLIDPAAMASPHR
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CHLTE
Sequence: MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVRVLFTVGKKLVPRAVDRNRIKRLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARADAIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CSRA_ECO24
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: RBSD_AERHH
Sequence: MKRGVLLNAPLSALVARMGHTDEITVCDAGLPIPAGPERIDLALMAGTPSLETVLTALLTDLVVEKVIMASEIKQISPAAHQALVDQLEAHAAAQGKPITIEYCLHEAFKARSHQSKAIVRSGEVTPYANLILCAGVAF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_ECOLC
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPSD5_ECOLX
Sequence: MKLFKSILLIAACHAAQASATIDINADPNLTGAAPLTGILNGQKSDTQNMSGFDNTPPPAPPVVMSRMFGAQLFNGTSADSGATVGFNPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKIAGVSNSQLNALVTSKVKEVYQSNVNVYASLLQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDPERGSYVDIVVKRGNRVRSNVNLYDFLLNGKLGLSQFADGDTIIVGPRQHTFSVQGDVFNSYDFEFRESSIPVTEALSWARPKPGATHITIMRKQGLQKRSEYYPISSAPGRMLQNGDTLIVSTDRYAGTIQVRVEGAHSGEHAMVLPYGSTMRAVLEKVRPNSMSQMNAVQLYRPSVAQRQKEMLNLSLQKLEEASLSAQSSTKEEASLRMQEAQLISRFVAKARTVVPKGEVILNESNIDSVLLEDGDVINIPEKTSLVMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNGARVNAEDVDSLKPGDEIMVLPKYESKNIEVTRGISTILYQLAVGAKVILSL
What is the function of this protein?
Involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface.  May function as the periplasmic binding element of the PSA transport system, in which it transiently interacts with the membrane component of the transporter, binds polysaccharide and transports the polymer to a component in the outer membrane.
What are the official names of this protein?
Polysialic acid transport protein KpsD.
What is the protein family that this protein belongs to?
To E.coli K1 KpsD.
What are the subcellular locations of this protein?
Periplasm.
Protein: COX3_ONCMA
Sequence: MAHQAHAYHMVDPSPWPLTGAIAALLLTSGTAVWFHFHSLTLLTLGNVLLLLTMYQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHASLAPTPELGGCWPPTGITTLDPFEVPLLNTAVLLASGVTVTWAHHSIMEGERKQTIQALTLTILLGFYFTFLQGMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLLRQVQYHFTSEHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSGA_THEMA
Sequence: MNLRRRGIVVSFHSNMVTVEDEETGERILCKLRGKFRLQNLKIYVGDRVEYTPDETGSGVIENVLHRKNLLTKPHVANVDQVILVVTVKMPETSTYIIDKFLVLAEKNELETVMVINKMDLYDEDDLRKVRELEEIYSGLYPIVKTSAKTGMGIEELKEYLKGKISTMAGLSGVGKSSLLNAINPGLKLRVSEVSEKLQRGRHTTTTAQLLKFDFGGYVVDTPGFANLEINDIEPEELKHYFKEFGDKQCFFSDCNHVDEPECGVKEAVENGEIAESRYENYVKMFYELLGRRKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_PARD8
Sequence: MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVTVPDARTIMITPWEKKIIRDIEKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCKQEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEAEVQKIHDKFIKKIDELYAAKEKEVMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA1_CITBB
Sequence: MPVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHASQVPFYLIAIFFIVFDVEGAFILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGLDWGPSAMRARGKRS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 1, NADH dehydrogenase I subunit A 1, NDH-1 subunit A 1, NUO1 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DDL_HALHL
Sequence: MSGIPDPQRVGRVAVLMGGTSAERDISLRSGGAILAALQRCGYDAEAYDPRDRALEGLRGYDVVFIALHGRGGEDGTVQGLLDLLGIPYTGSGVLGSALGMDKWRCKRLWQGSGLPTPAGQLLTGDRPVLDEGVGYPVIVKPAREGSSLGMSRVEGPEELAEAYRVAAAYDDTVLAEAWVEGEEYTVALLGDQALPSIRLETPHAFFDYAAKYQAEDTGHHCPSGLGPEEEAELGALCREAFIASGGNGWGRVDVMRDTGGRWWLLEVNTIPGMTDHSLVPIAAAQAGIGFDELVARILGEALR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBB2_AMBCE
Sequence: SSKWEACCDRCACTKSIPPQCHCADIRLNSCHSACESCACTHSIPAQCRCFDITDFCYKPCSG
What is the function of this protein?
Inhibits trypsin, chymotrypsin, plasmin and factor XIIa.  Does not inhibit factor Xa, thrombin, human plasma kallikrein, porcine pancreatic kallikrein and human urinary kallikrein.
What are the official names of this protein?
Bowman-birk type proteinase inhibitor 2, TcTI2.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: TRUA_STRA1
Sequence: MTRYKAQISYDGSAFSGFQRQPNCRTVQEEIERTLKRLNSGNDVIIHGAGRTDAGVHAYGQVIHFDLPQARDVEKLRFGLDTQCPDDIDIVKVEQVSDDFHCRYDKHIKTYEFLVDIGRPKNPMMRNYATHYPYPVIIELMKEAIKDLVGTHDFTGFTASGTSVENKVRTIFDAKIQFEASKNLLIFTFTGNGFLYKQVRNMVGTLLKIGNGRMPISQIKTILQAKNRDLAGPTAAGNGLYLKEIIYEDEECFSNFRK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: COBT_MYCA1
Sequence: MEFATVSPPDPGAAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVVFAGDHGVARCGVSAYPPEVTAQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDRIGANKVRRGSGDITVQDALTAEETERALSAGAAIADEEVDAGADLLIAGDMGIGNTTAAAVLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLAALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALDLEPILDLRMRLGEGTGAALALPIVRAAVAALSSMATFAQAGVSDPSAHP
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: NADK_METHJ
Sequence: MNILIVNRYGDPDVEEFSYELEKLLHHHGHHTSIYKENLLGEAPPLFSGEHPPDLVIVIGGDGTILLTTQRMPVQVPIIGINYGEVGFLADIEPEEMSTFVSHLTEPLPLEARMRIELRINGQHIGTALNEALIVTDRPAKMLKFLIHINGNVAERFRADGLIISTPTGSTAYAMSAGGPIVDPRVEGFLMVPLAPFMLSNRPHLIDSSRTVSITLEATKPAKLVIDGQTEIHLETSSTIELSKSPSPALFIDAGQNFFEKINRKLRHL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INS_MELGA
Sequence: AANQHLCGSHLVEALYLVCGERGFFYSPKAGIVEQCCHNTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_PSVJ
Sequence: MASKGSGNGSRRPRRGRRSFPIKEDAHARELRAVTAQLNRLVALTAARMPTLDHPTFVSSRKCAKGYTYTSLDVRPTKTEKGHSFGQRLNLPVPVSEFPKKKVSCVQLRLNPSPTFDSTVWVTLRKLPLGYSLASESVFKLFTDGLSAVLMYQHVPNGIQRDNKIIYDLSPVGTEIGDMSEYAIIVYSKDDTLEDDEILIHVDVEHQRIPSATALPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RL36_PSEE4
Sequence: MKVRASVKKLCRNCKIIRREGIVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.