PharMolix/UniProtQA huggingface dataset:
Protein: SYA_PYRCJ
Sequence: MQKTQMLSAEIFRRRGHIRKQCPLCKSHFWTLRPDQEVCGDQPCTPYGFIGNPPTKVAVESLRDVRERFLSFFERHGHARIKRYPVVARWRDDVYLVGASIYDFQPWVTSGAVPPPANPLTISQPSIRLTDVDKVGRSGRHLTGFEMMAHHAFNYPDKYVYWIDETTEYAYRFFTEELGIPPEEITFKESMWEGGGNAGECFEVLVRGLEAATLVFMHYEVKDGKYVELPLKIVDTGYGLERIYWLIKGTPTIYDAVFGPYLAKVRERLGVPEPPRDVMAKASIYFGQMDPEVISLDKAYDIIAEKIGVDGKWLREVVKPQEALYVLADHSRTVAWMIADGVIPSNSGAGYLARLLIRRALRGLMLAGVDAPLVELFDLHLKELRYDYPEVWEARSLILELVDMEEKKYREVLKSAPAVVKRALEENRRRGKAGLDKEDLVTLYDSYGLPPEVVAEAAKSMGIEVKVPDDFYSLLASRHVRREKGREATLVEMAKVADLPRTRELFYEDAYMRTFKAKVLRVIDGKYVVLDQTAFYAEGGGQPADTGVLRHSGGVAKVVDVQRVGHVIVHVVEGDVPQEGSEVVGEVDWERRYALMKMHTGTHVLIQSIRRVLGPHIWQAGAQKDIPFSRIDVTHYKLPTPEEVAKIERLANDVVQRDLPVYVKVMPRNEAEAKYGFILYQGGVVPAREIRVVQIGPDDEPYDVQACGGTHLRRTGEIGLIKVHKVERIADGVVRFIFTTGPHAVAYVQELERQAAEAAALGGGSKEELVEVVKRLLKRAEEAEKKARHYAELYAAALAENLKAEAVGQRRLAVVELDDEELAKRVALLATKRDPDLVLVVKAGERVTIYTGGVDVGPIVKALREIGFRGGGSKTFAQGVYAGDVEKLKEAIRRAL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_FRATM
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPINSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSLLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: GLPB_KLEP7
Sequence: MKFDCAIIGGGLAGLLCGLALNQHGLRSVIISRGQSALHFSSASLDLLSALPNGDHVTDVAQGLQQLAEQLPEHPYSRLGAEAVLKYATQTEALLAACGAVMQGDARRPHRRVTPLGTLRPAWLSPLEVPVAPLPSQGACLVGISGFADFQPHLAAAALGQHGVTAAAVEIELPLLDVLRDNPTEFRAANIARVLDDENMWPALHAALLPLAQQYDLLIMPACFGLADDRLYHWLQARLPCPLRLLPTLPPSVPGMRLHSQLQRQFIREGGAWLAGDEVVKISHRQDAVEAVWTRNHGDIALRPRFTVLASGSFFSNGLVATRDSVREPILGLDLHQTLPRESWYQRDFFASQPWQRFGVKTDALLRPLLGGQPFHNLFAIGSLLGGFDAIQLGCGGGVCAVTALHAARQIHALAGGRP
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: PURA_PLAFA
Sequence: MNIFDHQIKNVDKGNVVAILGAQWGDEGKGKIIDMLSEYSDITCRFNGGANAGHTISVNDKKYALHLLPCGVLYDNNISVLGNGMVIHVKSLMEEIESVGGKLLDRLYLSNKAHILFDIHQIIDSIQETKKLKEGKQIGTTKRGIGPCYSTKASRIGIRLGTLKNFENFKNMYSKLIDHLMDLYNITEYDKEKELNLFYNYHIKLRDRIVDVISFMNTNLENNKKVLIEGANAAMLDIDFGTYPYVTSSCTTVGGVFSGLGIHHKKLNLVVGVVKSYLTRVGCGPFLTELNNDVGQYLREKGHEYGTTTKRPRRCGWLDIPMLLYVKCINSIDMINLTKLDVLSGLEEILLCVNFKNKKTGELLEKGCYPVEEEISEEYEPVYEKFSGWKEDISTCNEFDELPENAKKYILAIEKYLKTPIVWIGVGPNRKNMIVKKNFNLN
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CAMLR
Sequence: MKKDIKKVVLAYSGGLDTSIILKWLQDEYKSEVVTFTADIGQGEELEPARKKALSLGVKEENIFIKDLKDEFVKDYVFAMFRANAIYEGEYLLGTSIARPLIAKALVEIANKTNADAISHGATGKGNDQVRFELGALALNPNLAIIAPWREWDLNSREKLLAYAQKHGIDIVKKADKSPYSMDANLLHISYEGLVLEDPAAKPEADMWRWVRDLKQTPNESEVIELEFSKGDLCAINGEKMSPAQLLAKLNELGAKHGIGRLDIVENRYVGMKSRGCYETPGGSILLKAHRAIESITLDREAAHLKDELMPKYASLIYNGYWFSPERLMLQALIDESQKHVNGKVKLELYKGNVMVIGRESANDSLFSEAYCTFEEDSVYDQKDAAGFIKLNALRFIIAGKNGRKF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSSC2_ECOLX
Sequence: MKSKLIILLTLVPFSSFSTGNNFEINKTRVIYSDSTPSVQISNNKAYPLIIQSNVWDESNNKNHDFIATPPIFKMESESRNIIKIIKTTINLPDSQESMRWLCIESMPPIEKSTKINRKEGRTDSINISIRGCIKLIYRPASVPSPVFNNIVEKLKWHKNGKYLVLKNNTPYYISFSEVFFDSDKVNNAKDILYVKPYSEKKIDISNRIIKKIKWAMIDDAGAKTKLYESIL
What is the function of this protein?
Involved in the biogenesis of the CS6 fimbria.
What are the official names of this protein?
Chaperone protein CssC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GDF8_PAPHA
Sequence: MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEALGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1B_PYRAE
Sequence: MSAEVALVYRVLPDSAEVNIEKLKNDVINKLAPKYKVDKVEVEEIGFGIKALRLYIRMPESDEYSSDEIEELLRSVEGVGGYELEYFSRLSF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: LAEA_ASPFU
Sequence: MFLNGQGGQRPPMVAFPPLNVRGSISSGFNALGRSRNNSDAMDIYTITDRGPAAERDPAAGRWHANGSPSINSTSSKNPDRYPCYQENGRTYHGYRKGIYMLPCDEQEQDRLDIFHKLFTVARVSDGLIYAPHPTNGRFLDLGCGTGIWAIDVANKYPEAFVVGVDLAPIQPPNHPRNCDFYAPFDFESLWALGEDSWDLIHMQMGSGSVASWPNLYRRIYSHLRPGAWFEQVEIDFEPRCDDRSLEGLAIRQWYQLLKQATEETMRPVAHNSRETIRNLQEAGFTEIDHQMVGLPLNPWHEDEHERRVARWYNLAISESIETMSLAPFSRVFGWPIERIKQIAADVKSEAFNKEIHTYNILHIYQARKPLAN
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:15075281, PubMed:17630330, PubMed:19843884, PubMed:24082142, PubMed:24116213).  Positively controls expression of 20% to 40% of major classes of secondary metabolite biosynthesis genes such as nonribosomal peptide synthetases, polyketide synthases, and P450 monooxygenases (PubMed:17432932).  Controls the expression of the gliotoxin gene cluster (PubMed:15075281, PubMed:17630330, PubMed:19843884).  Controls the expression of the fumitremorgin, fumagillin, and pseurotin gene clusters, where genes for fumagillin and pseurotin are physically intertwined in a single supercluster (PubMed:24082142).  Regulates the biosynthetic genes required for endocrocin production (PubMed:22492455).  Secondary metabolites under the transcriptional regulation of laeA are necessary for inhibition of angiogenesis during invasive infection in mice (PubMed:19843884).  Controls the expression of cell surface rodA, a hydrophobin that acts as an antiphagocytic molecule (PubMed:19917717).  Regulates also the expression of genes involved in conidial biosynthesis (PubMed:16151250).
What are the official names of this protein?
Secondary metabolism regulator laeA, Methyltransferase laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXT_PYRAR
Sequence: MKVGVLALQGDVEEHLEAFRRAAAELNISAEAVRVKRADQLDGLSALAIPGGESTTIGKLAQRLGILDRLRTVVESGVPTLATCAGAVLLAKEVRDSVVGPTGQPLLAVLNAAVVRNAYGRQRDSFEANVDVEGIGTVRAVFIRAPIFAKTWPPARAIAHVDHPRAGRAIVAVRQDHVLATAFHPELTTTAFHKAVLEMAAGRL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: YIDD_VIBA3
Sequence: MASPVSPFAWIALIPIYFYRWFISPLIGPRCRFTPTCSLYAIEALKAHGFVKGCWLSGKRLLKCHPLNEGGFDPVPPVQKQDRDK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GARL_ECOLI
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: IGF1_CAVPO
Sequence: MHAVSSSHLFYLAFCLLVLTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts.  Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  May play a role in synapse maturation.  Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.  Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor I, IGF-I, Somatomedin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAP1_MYCPN
Sequence: MVYLKSAREVEQIRQACKIFQEAKAYFTIERLLGKSLTAIDQALKQFIESKGATCAFHKYQNFPGFNCLSLNETVIHGIADNRVFGVKDKLTLDIGINLNGYICDAAFTVLGPKAPEPMQTLLEVTEACFTAVVEPQLRPNNPTGNVSHAIQTYFESKGYYLLKQFGGHGCGIKVHEEPLILNYGKPDTGTKLEPGMVLCIEPMVMTDSDAMVMHNNSWNVLTPKSRYNCHVEQMYVITTSGFECLTN
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: TRMB_STRPS
Sequence: MRVRNRKGATELLEANPQYVVLNFLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: GLMU_ACAM1
Sequence: MIAVAILAAGKGTRMRSNLPKVLHQLGGKSLIERVLSSTQNLSPSRQIVIVGYSADQVRTEMQGWPNLEFVEQTEQLGTGHAVQQVLPVMEGFEGDLLVLNGDVPLLRPGTLQKMLATHQEHQNAATILTAQLPNPKGYGRVFCDAQMHLQEIIEDRDCTPAQRQNQRINAGVYCFRWSALAKVLPNLKAENDQKEYYLTDAVNYLDPVMVLDVDDYQEILGINDRKQLATAYKILQDRIKDDWLVAGVTIMDPDSITIDETVELGTDVIIEPQTHLRGDTKIDTGSRIGPGSLIENSHIGTNVQVLYSVISDSRVGDNSRIGPYTHLRGNVQIGEKCRVGNFVEMKKTTIGDRTNVAHLSYLGDATLGTQVNIGAGTITANYDGVNKHPTQIGDRTKTGANSVLVAPITLGANVTVAAGSTITKNVDDDVLVVARQRQSVLPGWRPISSKQTEK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYC_PIARV
Sequence: MGQIVTLIQSIPEVLQEVFNVALIIVSVLCIVKGFVNLMRCGLFQLVTFLILSGRSCDSMMIDRRHNLTHVEFNLTRMFDNLPQSCSKNNTHHYYKGPSNTTWGIELTLTNTSIANETSGNFSNIGSLGYGNISNCDRTREAGHTLKWLLNELHFNVLHVTRHIGARCKTVEGAGVLIQYNLTVGDRGGEVGRHLIASLAQIIGDPKIAWVGKCFNNCSGDTCRLTNCEGGTHYNFLIIQNTTWENHCTYTPMATIRMALQRTAYSSVSRKLLGFFTWDLSDSSGQHVPGGYCLEQWAIIWAGIKCFDNTVMAKCNKDHNEEFCDTMRLFDFNQNAIKTLQLNVENSLNLFKKTINGLISDSLVIRNSLKQLAKIPYCNYTKFWYINDTITGRHSLPQCWLVHNGSYLNETHFKNDWLWESQNLYNEMLMKEYEERQGKTPLALTDICFWSLVFYTITVFLHIVGIPTHRHIIGDGCPKPHRITRNSLCSCGYYKYQRNLTNG
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: PPNP_HERAR
Sequence: MTTQFDNVSVVKKANIYFDGKCVSHTVLFADGTKKTIGIIFPSTLKFNTGAAEIMELNAGKCRIRLAGATEWNTYEGGQQFEVPANSSFDIETVDTLDYVCHFI
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: SYS_NOVAD
Sequence: MHDIRLIRENAEAFDAALARRGVGPVAQSILSLDSRRREIATRMQEVQARRNEASKAIGAAMGKGDKDTAEALKAEVAALKVELPALEEEERQLTAQQNAALAAYPNTPAADVPEGADEADNVEVSRWGTPRDFAFAPKEHADLGPALGLDFETGALISGARFTFLKGQMARLHRALAQFMLDRQTGENGYMECIPPLLVKDEAVFGTGQLPKFAEDLFRTTDGRWLIPTAEVSLTNAVQGQILGEAQLPLRMTALTPCFRSEAGAAGRDTRGFIRQHQFEKVELVSITRPEDSESEHERMTQCAEGILQALGLPYRKVLLCTGDMGFTARKTYDLEVWLPGQGAYREISSCSNCGDFQARRMNARYRPEGAKGTEFVHTLNGSGLAVGRTLVAVLENYQQEDGSVAVPEVLLPYMGGLARLTPQG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANC_ASPTN
Sequence: MLINFEKVLSLALLAGSVSGRKHVPRGFVTTSGMKFQLDGKDFYFAGSNAYYFPFNDNQTDVELGLAAAKQAGLTVFRTWGFNDKNATYIEGGLPAYGGEGAGTTEVVFQRWANGTSTIDLEPFDKVVNAAKNTGMKLVVALTNNWADYGGMDVYTINLGGQYHDDFYRLPAIKKAYKRYVKEMVTRYRDSPAIMAWELANEPRCGADGVRNLPRSADGCNPEVLTAWIDEMSTYIKKLDPHHLVTWGGEGGFNIESDDWAYNGADGGDFDNELALPNIDFGVFHSYPDWWSKTVSWTNQWIRDHAAAMRTGRKPVVHEEYGWLTPEARLEYLGTVSNITRLEAVGGWQQISVSEKMSDMYWQYGYSGYSYGRNHNDGFTIYLDDPEAKELVYKHAKEVKKLNRRH
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase C, Endo-beta-1,4-mannanase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_ECOLC
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MTGA_DESHY
Sequence: MFKFTAQQHVYDINGVKVGGQPGEYPTVLIGSIFYRGHKIVSDGQKGIFDKDAAKALLDQEAELSAETGNPFIIDVLGESVEALTKYVEFILENTTAPFLLDSISPDVRVGALKNLGKDPEIQKRLIYNSIEEHYTEEELAAIKEAGLKTAVILAFSKKALKPNARIDLLQGKDDKEGLIAAAKRAGIEQFLVDPGVLDVASNSWTTEAINVVKEQFGYPGGCAPSNAVYLWKKMRSKGTPFFEVAGAAVFTYPITQGADFILYGPMMNAPWVYRAIATTDAMIAYNNKLTGVKMGTTEHPLLKIF
What is the function of this protein?
Methyltransferase able to catalyze the transfer of a methyl group from methylcobalamin (methylCbl) to tetrahydrofolate (THF) in vitro, to generate methyl-THF and cob(I)alamin.  In vivo, the methyl group probably comes from the adjacently encoded methylated corrinoid protein DSY3155.  The methyl group may then be ultimately converted to carbon dioxide, and its oxidation would also provide reducing equivalents for anaerobic respiration.  Thus, may function in the pathway that allows anaerobic methylotrophic growth of D. hafniense using glycine betaine.
What are the official names of this protein?
[methyl-Co(III) glycine betaine-specific corrinoid protein]--tetrahydrofolate methyltransferase, Methylcobalamin:tetrahydrofolate methyltransferase, MethylCbl:THF methyltransferase, Methylcorrinoid:tetrahydrofolate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MtrH family.
Protein: PETG_POPDE
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS18_STUS1
Sequence: MARFFRRRKFCRFTAEGVKEIDYKDLNTLKAYISETGKIVPSRITGTKARYQRQLATAIKRARYLALLPYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.