PharMolix/UniProtQA huggingface dataset:
Protein: RS15_RICM5
Sequence: MSITTERKQQLIKEYAITENDTGSSAVQCAILTERINNLTEHFKSNHKDHTSRRGLLILVGRRRRLLNYIKKNNVSKYLDLISKLGIRKIK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RBL_BETPA
Sequence: MSPQTETKASVGFKAGVKDYKLTYHTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TATB_NOVAD
Sequence: MFDIGASELLVLVIVAIVVIGPKDLPLALRTAGRWVAKMRRVSNHFRAGIETMIREAEMEEMERKWKEQNERIMRETAAQETAAAQGQTPAAAEDQNDPFPTPLAADAPHTDPVMTGPMPPEAKVEARVEEAPAARPGSQQP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PEPQ_YERPA
Sequence: METLASLYNEHLSTLQQRTRDVLERHQLDALLIHSGELQRLFLDDRDYPFKVNPQFKAWVPVTEVPNCWLWVDGVNTPKLWFYSPVDYWHSVEPLPDSFWTKNIDVQPLLNADDIAQQLPVQRERVAYIGYAQQRAQALGFSAENINPQPVLDYLHYYRSYKTDYELACMREAQKTAVVGHRAAYEAFQSGMSEFDINLAYLMATGHRDTDVPYDNIVALNEHSAVLHYTILQHQPPAEIRSFLIDAGAEYNGYAADLTRTYTADRDSDFAALISDLNTEQLALIDTIKSGERYTDYHVQMHQRIAKLLRTHNLVTGISEEAMVEQGITCPFLPHGLGHPLGLQVHDTAGFMQDDKGTNLNAPSKYPYLRCTRVLQPRMVLTIEPGLYFIDSLLAPWRIGEFSKHFNWDRIDALKPYGGIRIEDNIVIHDKRVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: LGSN_RABIT
Sequence: MNDEGDLLQEDTARDEVNETEASRMSKLRKTRKKVTKPHDYSTEVGEMDISNSNERIRSQMLCHQLGDTSKPVAGPSSSETRVSQDDKDSPDQTMVMKPLPPQTASVPSGEHNTNSDCTRDSTQILTPPQLSSRMKHIKQEMAKNHLQFVQFEASDLHGVSRSKSIPAHFFQEKVIHGVFMPRGYLELIPNPKDNEVNHIRATCFNNDIVLMPELSTFRVLPWAERTARVICDTFTVTGEPLLTSPRYIAKRQLNQLQDCGFSLLSAFIYDFCIFGVPEIINSKTISFAASTLVNNHDQPFMQELVDGLYHTGASVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCNSGILSHSLWDVDGKKNMFCNSSGVEQLTIIGKKWLAGLLKHSAALSCLMAPAVSCRKRYSKETKDLKESVPTTWGYNDNSCAFNIKCHGDKGARIENKLGSATANPYLVLAATVAAGLDGLQSNLDDLAGPDDSTDLFQSEPSEIPLKLEDALVALEEDECLREALGETFIRYFVAMKKYELENEETDAERNKFLEYFI
What is the function of this protein?
May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens.  Does not seem to have enzymatic activity (By similarity).
What are the official names of this protein?
Lengsin, Glutamate-ammonia ligase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
Protein: YL085_MIMIV
Sequence: MLINKFKKDLKLKEYTDLTIVLKDDTCEIEMNVHKTVICIMCKYFENFIKFNSQTEKKSNDKLTVIVPNALITRDIIRNFYDKTSTNSEYPLWRYTLEKIMCRDFLMLDYDSEIIKDLEKIPSEGITLFLEVLSITNYEFSLMTLLKKNISKGYNFKNIPSKIIDELYSYTKPNIIVCMGNENNLELWNIETNKLINNIKLDKPFHHTTNIVCSQNESIIAISDGQTFGLINVLKNTCIYKTYQSKIKYSSSNDSDEDASETESEHNSETESEHNSETESEHNSETESKHNLETKIDLKYNVGNFIKFSRSHNKIIFERDNEIFLWKIIFFPNYECSSYDYNKKKYGCDYYNSYDKKKYKCVVNIDGFPNDKLLYAKKINNFNPKHIYTIYGIKGNEQKTIIFDVPIKIAKYLPMVKIS
What are the official names of this protein?
Putative BTB/POZ domain-containing protein L85.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.
Protein: BOL2_YEAST
Sequence: MTGERIEKVKINDEFAKSHFLTTQWRETKRQRHYKMPVTEQGLRERIESAIPQVYHIIVTDLSYGCGQSFDIVVVSDFFQGKSKLMRSRAVNKAVKEELQEIHAFSCKCYTEEEWSKIVV
What is the function of this protein?
Involved in the regulation of the iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis.  May be involved in mitochondrial organization and biogenesis.
What are the official names of this protein?
BolA-like protein 2, Altered inheritance rate of mitochondria protein 15, Fe repressor of activation 2.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NEP_I76A2
Sequence: MDSNTITSFQDILQRMSKMQLESSSVDLNGMITQFERLKIYRDSLGESVMRMGDLHSLQSRNATWREELSQKFEEIRWLIAECRNILTKTENSFEQITFLQALQLLLEVESEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: T10B_XENLA
Sequence: MEGEQQQLRNLRDFLLVYNKMTELCFSRCAKNLNYRSVTMEEEQCLDSCASKFIRANHRLMSAYVSLMPSVVQRRMAEYEGAAANVPPIETEPSADHMPPVISSHSGNSPTNKQLDSVSDLPVGK
What is the function of this protein?
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10 B, Mitochondrial import inner membrane translocase subunit Tim9 B.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: RL1_PARPJ
Sequence: MAKLSKRLQAFAAKVDRQKLYAIDEALSLVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEVVGMEDLAEQVKAGKLDFDIVIASPDTMRVVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRSNLNALVDALQKAKPATSKGVYLRKVALSSTMGVGVRVDQASIAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: COAD_LIMRJ
Sequence: MKVAVFPGSFDPLTLGHLDLIKRGSALFDQLAVAVMTNESKNPLFTVEERVAQIKEAVSGLDNVSVITTEGLTVDLMNRIGADYLMRGLRNTTDFQYERDIAAMNNFLDDQCETVFFLAKPEYQHLSSSLLKEVTSAGGDISAYLPANINEALKKRLMEREMLRVKKDNEKAR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDB19_FUSPC
Sequence: MTDAEVIPLTKGLAALQTALPFIVGCGSGMVATTCVQPIDTIKVRLQLADRSVLRVTTWSIARDLMVEGGILNMYQGLSAAIMRSLVYGTMRLGLFSTFEKELARRARERGTTLSFGERSLAGVGAGALAAVVGNPTEVILIRMQTDGLKPLSQQARYSSAVDALRRIASHEGVLALWKGAGPTLIRAMSINFGQLTSFSEAKNQLQEHTSLSPPVRTAVAAGIAGCLGALISQPFDFVKTRLQNQVKTSPTVGLGSGELLYKGTFDCLFKVIHKEGLFRLYRDILPYFMRIGPHS
What is the function of this protein?
Solute carrier protein; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).
What are the official names of this protein?
Solute carrier protein FPSE_08119, Fusarium detoxification of benzoxazolinone cluster protein FPSE_08119, FDB cluster protein FPSE_08119.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPIA_PSEPK
Sequence: MTQDQLKQAVAQAAVDFILPKLDEKSVVGVGTGSTANFFIDALAQHKTAFDGAVASSEATAQRLKGHGIPVYELNSVSELEFYVDGADESDAHLHLIKGGGAALTREKIVAAVAKTFICIADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVVTDNGNVILDVYNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKSLKAE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYY_CLOP1
Sequence: MANVLDTLMERGYIKQFTHEAETRELLEKEKVTFYIGFDPTADSLHVGHFIAMMFMAHMQKAGHRPIALIGGGTATIGDPSGKTDMRKMMTNETIAHNVACIKKQMEKFIDFSDDKAILVNNADWLLNQNYVEFLREVGVHFSVNRMLSAECFKQRLERGLSFLEFNYMLMQGYDFYVLNKKYNCKMELGGDDQWSNMIAGVELVRKKSQESAYAMTCTLLTNSEGQKMGKTVNGALWLDPEKTSPYEFYQYWRNVNDADVEKCLKLLTFIPMDEVRRLSSLEGSQINEAKKVLAFEVTKLVHGEEEATKAKQAAEALFGKGGDMSNVPTYEMGKDKLGSELLDILVEAEIVPSKAEGKRLVKQGGLSLNGEKVADFKKTLEEADFENGEVLIKRGKKNYNKIVLA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_SHESM
Sequence: MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEGSFTVDTITKASRGTEITLHLRDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKATALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNRDRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAAPTVSLDDYLSRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHLTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLVERIKAALGASVADVKVTSRLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_ERWT9
Sequence: MSSSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQQHAAGHRIVIVTSGAMAAGREHLGYPELPPTIASKQLLAAVGQSRLIQLWEQMFSIYGIHIGQMLLTRADLEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRNNPQAELIRDVRGIDDDLRALAGDSVSGLGTGGMATKLQAADIACRAGIDTIIAAGSRPGVIGDVIASHPVGTCFHALETPLENRKRWIFGAPPAGELVVDDGALSAILERGSSLLPKGIREISGNFSRGEVIRIRSLQGRDVAHGVSRYNSDAMRMIAGHHSQQIGEILGYEYGPVAIHRDDMIVS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFJS_ECOLI
Sequence: MKRKTLPLLALVATSLFLSACDDRSDDLKAISKFKDLTPPRFSDVVSRQDDVSEEWSQVGFSSGLTLQVLRTRESPDGCEGGSYYYLVDMEEKTVQPLMNALCIADNIKLEYHEVTDPYTKEKYFEYSHDGKLMGRLLIPSNPDNRE
What is the function of this protein?
Does not induce degP when overexpressed unless it is mutated to resemble YafY.
What are the official names of this protein?
Lipoprotein YfjS.
What is the protein family that this protein belongs to?
To E.coli YafY.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: DNAA_BIFLO
Sequence: MVNASGDPVIEAAHIWSDTLTVLKHSASLSPREKGWLEGVVPEGVFGSTIVLCVDNNDTLQAIQGDLNDSLLQALRTVTGENMFPAFKVVPKTEPEPLSEAKPAQPYPSEISPTVAEFGKESYGAKPAAAPREPMPATEPQFPVGQQKMNRDPETHLNKNFTFDSFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPGLKVRYVTSEEFTNEFIDALQNPNQSQGQIAEFNRRYRQVDVLLIDDIQFLGGKEATLDQFFHTFNALHQANKRIVIASDVAPKNLKGFEARLISRFESGLTVDVKPPDLETRIAILRMIASMNGSKIPSDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTRALAEQTLQDFFTTDVEIKPTDIISQVAKYFHLTFEDLVGKSRTKNVAVPRQIAMYLAREMTSMSLMDIGQVFGGRDHTTVMHACTRISDRMQQKQEIYNYVMELTVRLKQSNTN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTR1_STRCA
Sequence: LFCRKGTCHFGGCPAHLVKVGSCFGFRACCKWPWDV
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria S. aureus 1056 MRSA (MIC=1. 25 ug/ml) and S. aureus NCTC 4163 (MIC=6. 7 ug/ml), and the Gram-negative bacteria E. coli O157:H7 (MIC=0. 96 ug/ml) and E. coli 0111 (MIC=6. 7 ug/ml).  Does not have antifungal activity against the yeast C. albicans 3153A.
What are the official names of this protein?
Ostricacin-1, Beta-defensin 2.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFNA3_HUMAN
Sequence: MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS
What is the function of this protein?
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
What are the official names of this protein?
Ephrin-A3, EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, LERK-3.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: HEM1_BACCN
Sequence: MHILVVGVNYRTVPVEIREKLTFQETELKRAMTTLQSQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLEIEEISPYLSIFEQDGAIEHLFRVTCGLDSMVVGETQILGQIRNSFLTAQEVKTTGTIFNELLKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGDLTDCHVLILGAGKMGELALQNLYGSGVQKVTVMNRTFTKAETMAEKYMGHAKPLSELQCALLEADILISSTGSSNYVITKEMMKKVERMRSGRPLFMVDIAVPRDIDPEINELEGSFLYDIDDLQDVVEANRAERLKEAEKIQFMIEEEIVLFKNWLNTLGVVPLISALREKALGIQSETMRSLERKIPTLSDREKKVISKHTKSIINQLLKDPILVAKELAAEEKATEKLALFAKIFDLEVQEEVEHTEELEHKRAWTPSVSSL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SYP_LEGPA
Sequence: MRASQWFLVTQKETPNDAEIASHQLMLRSGMIRKLGSGLYTWMPLGLRVLRKVENIVREEMNKTHAMELLMPSVQPAELWQETGRWETFGGQLLTMKDSNQREYCFGPTHEEVITDIMRNELQSYKQLPVNFYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHLSLESLQETYKDMYQAYCRIFDRMGLKYRAVEADTGAIGGSASHEFQVLAESGEDLIFYSDASDYAANIEQATSLKPPKANQACNETITLVDTPNQKTIDEVASFLGIASNQTIKTLIVKGKEHPMVALVLRGDDELNEVKATKHPLVHSPLSFIDEELILKTLKTPLGSIGPIQLNIPVIVDHHALAMPSFVCGANQADKHFINAAWERDAKYDDAYDLRNVKEGDQSPDGRGTLHCCRGIEVGHVFQLGDKYAKAMNASVINEQGQLQTMIMGCYGLGITRVVAAAIEQHHDEHGIIWPQALAPFQVNIIPLNGARSQTVKEQAESLYQQLKSHGIDVLLDDRNERAGVLFADNDLIGIPHRLVVSERNLEQGCIEYKSRTSSETQLINLDKVVNFIIELINK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_DROPS
Sequence: MSTTNAINGNLYEQLHQGRTNMYKSKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDEVLKNEAKGLQHLEHRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNAFSDKFKLIVATHLRLFPSINVDVEAELTRYRDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPSEQLNEIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLRYTSLVNGYTCICLTKLDILDTLPEIKVAVSYKKANGDKLDHFPGTIAELGNIEVEYAVLPGWQTSTEHIRNFKELPENAQNYVRFLEKELSVPVRWVGVGKGRESIINVH
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_CHLAD
Sequence: MEGLNLVATALAVGLGAIGPGVGIGIIVSGAVQAIGRNPEIENRVVTYMFIGIAFTEALAIFGLVIAFLIGFGVLQ
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL23_WIGBR
Sequence: MINKKENIFKILTSSYSSEKSSILSEKNNTFTFKVLKNSKKSEIKSSIEKFFNVKVKKVRTVMLKGKSKKHKNIIGKRKNWKKAYVVLKKNQKINLIKNIE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y032_MANSM
Sequence: MRRVVMTQLKLLFAVFYCRFQQNKLTQAAGALTYSTMLAIVPLVMVVFAIFSAFPMFNEAAAELKTFIFDNFSPSAGDTVGQYIDEFVVNSKSMSAVGIISLIAVALLLINQIDRTINDIWNSKNRNFIFSMTIYWTLLTLGPIFIGMSFAINTYIRSIIAFEGDLGLPFGLKLLSFVPFLLTWLSFSLIYTLVPNTKVNFRYAAVGALVAAIFFTLGKKAFAWYMATFPSYQLIYGAMATLPITLLWIQLSWLFILLGAQLTAVLGDMRLIKSGDLNLTAIKEKTE
What are the official names of this protein?
UPF0761 membrane protein MS0032.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RCL1_CAEEL
Sequence: MSSETLEFSGCNFFRIRLAYSILSGRPIRIINIRKNDDRPGIRDFESKLIGLLEKVTNGTKVEISRTGTQVIFRPGMITGGVVNLDCGTERCISYFLEPLLLLSPFCKVPMVIKLKGVTNAPGEISVDGMKASWLKVYNKFVLNDEKLDIKIQARGLKPEGGGVVVFTAPIVKTLRPVKRQQVGKVCKIRGQAYVTKVTPSLAYRMIDAAKKAMHGYISDVYITVDQRKGDAGGASPGYGLFLTAETTEGVIYQAEAISRPKGESGVPILPEDIGIEAGHALLQQIYMGGALDSSAQILASTFMTLCPKDVSHFLYGPLPMYSVHALRHLKQFFEIEFKMEDFKKTLKEEEADLKTGSADKAMVTAVGVGYSNLNKTIL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Does not have cyclase activity (By similarity).
What are the official names of this protein?
Probable RNA 3'-terminal phosphate cyclase-like protein.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.