PharMolix/UniProtQA huggingface dataset:
Protein: KDPA_BACHK
Sequence: MIWVAVVITMLLFILVAKPTGIYLEKAFQGSKKLDKVFGPFEKLIFKITGVKEYNQTWKQYALSLVLLNGFMIVVVYFIFRLQGVLPLNPAHIEGMEPTLAFNTAISFMTDTNLQHYSGENGLSYLSQLIGITFLMFAAPATTLALVMAFIRGLAGKELGNFFVDFTRALTRVFLPIAFVTALVFVALGVPQTLDGAVTAQTIDGVKQSIVRGPVASFVSIKELGNNGGGFFGTNSTHPFENPGQMSNILQMMLMMLLPTALPFTYGRMVGNKKQGRILFVSLFMVFLLGFITITTSELNGNPALNAMGIEHVQGSTEGKEVRFGTVFSSLYATVTTAAETGAVNTMHDTLTPIGGLVPLVNMMLNTVYGGVGAGFVNIITYAIIAVFISGLMVGRTPEFLGKKIEGKEMKLIAVTILFHPLLILGFSALALSTSLGTDAISNLGFHGLTQIVYEYTSSAVNNGSGFEGLGDATTFWNITTGLVMFLGRYFSLVTMLAVAASLKEKTVVPETVGTFRTDNGLFGGIFIGTIVIVGALTFFPMLVLGPIAEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPA_LIGS1
Sequence: MRKSYRVKKEAEFQTVFTQGQSCANRQFVVYMLEKPDQKHFRVGISVGKKIGNAVARNWVKRRIRQSLTELKPQLKQDCDFLVIARPTVAYMSMAEVKEHLKHVLKLAKVLGE
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MCPT4_RAT
Sequence: MKALLFLMALLLPSGAGAEEIIGGVESIPHSRPYMALLKIVTEEGHVTFCGGFLISLQFVLTAAHCHGREITVTLGAHDMSKRESTQQKIKVVKQIFPLKYNLFSNFRDIMLLKLEQKAVLTPSVNVIPLPQSSDIIKPGTMCLAAGWGQTGVKEPNSNTLREVMLRIMEMKACKDYRHYDNRFQICVGIPQMLKLAYKGDSGGPLVCAGVAHGIVSHGPGRGIPPIIFTRISSYVSWINRVIRGN
What are the official names of this protein?
Mast cell protease 4, rMCP-4, Mast cell protease IV, rMCP-IV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Secretory granules.
Protein: SLAM_PASMU
Sequence: MNLMINLKPLTFLPFFGRLVFLSGVIYNTAWANTVIPVDNSRPDETFSQTSPKQHLFSQKPKPTEPTSSASSQQISLTIEQLASRPDLVLRALIPALKNNDMRGVEILLPIYAKQSPDPFLLKWAQAVVARKQGKLNESVRLYRQIIAEKPNLQPARLQLAIALTQNRENEAAKAQFNQLRSENLPAPLLTLIDSYIDTINQRDSWNVYGGVNYLHENNVNNAPPKGTKAEGFTPSSQPEKAHGLSYFINLSKNWSLAHGFFTEFSADINGKYYWDNHKYDEFSTRLNLGGGYRNAKTEVKLMPFVEQFWYVGGENATKDARTLHRYSKSSGINLDVDYWLTPNWKISTVLEYTEQRYIQPQRQNSNGNSYSISNTLIYMPNSQQFWFVGLDYYQKNTRLKAYAFERQGIRLGWGQEWPKGISTRLQTSYATRTYRAPSAEKNMIFAPSFFKVVQKNHEYGVNFTIWHRSLHWLGITPKITWAYQKTTSNNPFSEYDRNRIYLTFSKTF
What is the function of this protein?
Required for correct export to the cell surface of some cell outer membrane lipoproteins (tested with PM1514) upon heterologous expression in E. coli and probably also in Pasteurella.
What are the official names of this protein?
Surface lipoprotein assembly modifier, Slam.
What is the protein family that this protein belongs to?
Belongs to the Slam family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: NUOK_BART1
Sequence: MYIDITHYLTVSALMFTIGIAGIFLNRKNVIIILMSIELILLSVNINFVAFSAFLHDLVGQIFALFVLTVAAAEAAIGLAILVVFFRNRGSIAVEDVNVMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_SYNE7
Sequence: MARAKFERTKPHANIGTIGHVDHGKTTLTAAITTVLAKAGMAKARAYADIDAAPEEKARGITINTAHVEYETGNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPNIVVFLNKEDMVDDAELLELVELEVRELLSSYDFPGDDIPIVAGSALQALEAIQGGASGQKGDNPWVDKILKLMEEVDAYIPTPEREVDRPFLMAVEDVFTITGRGTVATGRIERGSVKVGETIEIVGLRDTRSTTVTGVEMFQKTLDEGLAGDNVGLLLRGIQKTDIERGMVLAKPGSITPHTKFESEVYVLKKEEGGRHTPFFPGYRPQFYVRTTDVTGAISDFTADDGSAAEMVIPGDRIKMTVELINPIAIEQGMRFAIREGGRTIGAGVVSKILQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_FOAMV
Sequence: MAPPMTLQQWIIWKKMNKAHEALQNTTTVTEQQKEQIILDIQNEEVQPTRRDKFRYLLYTCCATSSRVLAWMFLVCILLIIVLVSCFVTISRIQWNKDIQVLGPVIDWNVTQRAVYQPLQTRRIARSLRMQHPVPKYVEVNMTSIPQGVYYEPHPEPIVVKERVLGLSQILMINSENIANNANLTQEVKKLLTEMVNEEMQSLSDVMIDFEIPLGDPRDQEQYIHRKCYQEFANCYLVKYKEPKPWPKEGLIADQCPLPGYHAGLTYNRQSIWDYYIKVESIRPANWTTKSKYGQARLGSFYIPSSLRQINVSHVLFCSDQLYSKWYNIENTIEQNERFLLNKLNNLTSGTSVLKKRALPKDWSSQGKNALFREINVLDICSKPESVILLNTSYYSFSLWEGDCNFTKDMISQLVPECDGFYNNSKWMHMHPYACRFWRSKKNEKEETKCRDGETKRCLYYPLWDSPESTYDFGYLAYQKNFPSPICIEQQKIRDQDYEVYSLYQERKIASKAYGIDTVLFSLKNFLNYTGTPVNEMPNARAFVGLIDPKFPPSYPNVTREHYTSCNNRKRRSVDNNYAKLRSMGYALTGAVQTLSQISDINDENLQQGIYLLRDHVITLMEATLHDISVMEGMFAVQHLHTHLNHLKTMLLERRIDWTYMSSTWLQQQLQKSDDEMKVIKRIARSLVYYVKQTHSSPTATAWEIGLYYELVIPKHIYLNNWNVVNIGHLVKSAGQLTHVTIAHPYEIINKECVETIYLHLEDCTRQDYVICDVVKIVQPCGNSSDTSDCPVWAEAVKEPFVQVNPLKNGSYLVLASSTDCQIPPYVPSIVTVNETTSCFGLDFKRPLVAEERLSFEPRLPNLQLRLPHLVGIIAKIKGIKIEVTSSGESIKEQIERAKAELLRLDIHEGDTPAWIQQLAAATKDVWPAAASALQGIGNFLSGTAQGIFGTAFSLLGYLKPILIGVGVILLVILIFKIVSWIPTKKKNQ
What is the function of this protein?
The leader peptide is a component of released, infectious virions and is required for particle budding.
What are the official names of this protein?
Envelope glycoprotein gp130, Env polyprotein.
What are the subcellular locations of this protein?
[Envelope glycoprotein gp130]: Host endoplasmic reticulum membrane. Note=The polyprotein has a highly unusual biosynthesis for a retroviral glycoprotein. It is translated as a full- length precursor protein into the rough endoplasmic reticulum and initially has a type III protein configuration with both its N and C- termini located intracytoplasmically (By similarity). SUBCELLULAR LOCATION: [Leader peptide]: Virion membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Its N-terminus is located inside the viral particle. SUBCELLULAR LOCATION: [Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM.
Protein: TSAD_LACLS
Sequence: MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITVCIEAALEEAEISADQLTAVAVTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLMAASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETRDDAAGEAYDKVGRVMGLTYPSGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLENLAASFQAAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLRLCGDNAGMIAAAAYIEWKKGLENVQAGLDLNAKPSLVFEDM
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BRUO2
Sequence: MIGKLKGVIDEIAEDHAVIDVHGVGYVAFCSARTLGNLGGAGEAAILFIETYVREDMIRLYGFATQLEREWFRLLQNVQGVGAKVALAVLGTLSPSELANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAFAGEASGTIGLKQELGAGAAPAPVADAVSALSNLGYSRDQAANAVAAALKETGEGADSAKLIRLGLKELSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: QUEA_BRASB
Sequence: MRTDLFDFHLPPENIALRPASPREAARMLVVQGDGVLRDRIVADLPDWLEPGDQLVVNDTKVIAAQLSGRRVSRETEAKIEATLIKRLDGSRWQALVRPAKKLAPGDTIRFGHEGKVCLLGHLDATVEAKGEEGEVTLSFVFHGPALDQAIADLGRPPLPPYIAGKRPADEQDAADYQTMFAAKEGAVAAPTAGLHFTPALEQRLRARGVGLQRVTLHVGAGTFLPVKVEDTEGHRMHAEWGSLSAETAAALNEARAKGGRIVAVGTTSMRLLESAALPDGTIAPFEAETSIFITPGYRFRAVDILMTNFHLPRSTLFMLVSAFAGLETMQAAYAHAIRSGYRFYSYGDACLLFRQPDERIVEP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_DESHD
Sequence: MKTRRQMKIQEIINNQVIHTQEELAELLRKAGFDVTQATVSRDIKEMGLIKVPTSEDDYRYAVPGTAQPLSTPDRLKRRLRETVVTVNDSENLVVLRTIPGNAQALASLIDHSNWEEVIGTVAGDDTILLVVKPAGAVPSVRERIAKLMQ
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ACTPJ
Sequence: MAGAKEIRTKIASVKNTQKITKAMEMVATSKMRKTQERMAASRPYSETIRKVISHIAKGSIGYKHPFLTERDIKKVGYLVVSTDRGLCGGLNINLFKATLNEFKTWKDKDVSVELGLVGSKGVSFYQNLGLNVRSQVTGLGDNPEMERIVGAVNEMINAFRNGEVDAVYVAYNRFENTMTQKPVIAQLLPLPKLDDDELDTKGSWDYIYEPNPQVLLDSLLVRYLETQVYQAVVDNLASEQAARMVAMKAATDNAGTLIDELQLVYNKARQASITNELNEIVAGAAAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROA_VIBC3
Sequence: MDLTVLGKAAKAASFQLATASTAQKNQALASMADQLEAQSASILAANAKDIALGREAGLSDAMLDRLLLNESRLQAIANDVRNVIKLNDPVGSEIDSRVLENGMSLARRRVPLGVVGVIYEARPNVTIDIAALCLKTGNAAILRGGKETFFSNMELVKVIQSALDKAGLPAASVQYIEKPDRELVTQLLKMDDYVDMIIPRGGAGLHKMCKENSTVPVIIGGFGISHIFVDESADLDKSVAVIENAKVQRPSACNALDTLLVHQAIAKPLLDKLIAKLNGKVAFVAEPKAKALMSSAAELRDAQAGDFDTEWLSYTLGVKVVQDVQEAIEHMREHNASHSDAIMTNDLYNAELFVNTAGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGKANYLSRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2284_STAAW
Sequence: MMKLNLFINAKETESYIDIHAPKMNDHVQSIINAVNDLDKSHTLVGYIDKEIHIINVSDVITFQVINKNVTAITSNQKFKLKLRLYELEKQLPQHFIRISKSEIVNKYYIEKLLLEPNGLIRMYLKDAHYTYSSRRYLKSIKERLSI
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MW2284.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8444_DICDI
Sequence: MAEYTHYFIQYNLTDIFYEDVNIEKYSCSICYESVYKKEIYQCKEIHWFCKTCWAESLFKKKECMICRCIVKSISELSRNRFIEQDFLNIKVNCPNSFKYIDENKNNNNKIKDLENGCKDIITIGEIEKHLKQCKFTHIKCKFIGCNKIIRLNQVEKHEKEQCEFRLEYCRYCDTDGITSRSLENHYKECPKFIVKCSENGCTVQLERSQLESHIEKQCQMVMIDCPYKIYGCEQSNRFPKSNLTQHLSSINHTLAMGSMIESQSLQIKETNIKYENLLNKINKLEQLETESKCDQLYDKFYQFESKIDKKLNNLQLDLYPKDNQQPQQKEQKEQKEQKEQQERIKFDDLFEKVSKVNSYFINGCLLKYKNRWSISNYLTESRKYRKITSPSFKIYDKKFKLVIYPQGKDDGSYTSLFLKSDSINPIKVFYKFVLLNFKDESKNLIFKNKSIMDKEKSVGCHYFIKSTEPGKKPEVWLKDDSLVIDFSIEVNINNDIKPLES
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0268444.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ECO57
Sequence: MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DNLI4_ASHGO
Sequence: MVIYPWLKNTTELTIALPKKPIIHANMDVLGSPRGGTPTGEHEINAQDGSPINFSPSPDFCWLCDELFIKLEEVALKKKDLGKPRKVRNLEITSNFVSLWRKTVGNDIYPALVLSLPYNDRRSYRVKDVTLVKALCKHMKLPRNSETERRLLHWKQNAPRGVKLSTFCVEELQKRRREPVVPKRMSIDEVNGMLDKLEHESNVGKWSYISLAESPAFNYCLEHMSYVELRFFFDIVLKVPIVSGLESLLLSCWHPDAESYFKVVSDLRIVAHTLYDPNERLEKNDLSVRIGYAFAPHMAQRVKIPYEKVSTKLGNDFYVEEKMDGDRIQVHYMDYGNSIAYFSRNGINYTYLYGENSSKGSISNHLKFVEGVKECILDGEMVSYDKEMQCILPFGLTKSGASHQVNFETTGHTEPTYRPLYAVFDLLYLNGQLLTNQDVVKRKEYLEKILIPSKNVVHLLSGPRCSDAEAITAALGAAVAHGSEGIVLKKARSKYSVGKRDDSWIKIKPEYLENFGENMDLVVIGRDKGRKDSFICALAVTDDSEKNNPSSYESGSDSDSDSEPIIVQPKIEKFISFCSIANGISNEEFKEIDRLTRGNWFPYDERKPPTDWVEFGTKTPREWIDPKNSVVLEVKARSIDNEESKSDLYKTGSTLYNAYCKRIRHDKNWSTASTVAEYDTAREARSYFNVSQNAKFGKDRSSPRKRRTFHLVGDIDVTKPSKADFLKGYYFYVTSGYFDLQSKKNIDASEIGEAVVSCGGTYIHNLRIRASLDKLYILGCKDTRELKMLIERGYDIIHPEWLMDCVKYGTMLQIEPKYVYSASEELMKQARNQEDKYGESYQLPVTEDTLKALANKQVEEGYASEMGTDAVSEYERLLIFKGWLFYILDDYAYHSSWSDIVKWNIESCGGEVTNDLELATIVVAVKDCFSQLSLQAVRNNIGARITGSNDVQPIPKIVTSEWVEACMEAQYLVDEDEYAAI
What is the function of this protein?
Involved in ds DNA break repair.  Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMNGT_SORBI
Sequence: MGSNAPPPPTPHVVLVPFPGQGHVAPLMQLARLLHARGARVTFVYTQYNYRRLLRAKGEAAVRPPATSSARFRIEVIDDGLSLSVPQNDVGGLVDSLRKNCLHPFRALLRRLGQEVEGQDAPPVTCVVGDVVMTFAAAAAREAGIPEVQFFTASACGLLGYLHYGELVERGLVPFRDASLLADDDYLDTPLEWVPGMSHMRLRDMPTFCRTTDPDDVMVSATLQQMESAAGSKALILNTLYELEKDVVDALAAFFPPIYTVGPLAEVIASSDSASAGLAAMDISIWQEDTRCLSWLDGKPAGSVVYVNFGSMAVMTAAQAREFALGLASCGSPFLWVKRPDVVEGEEVLLPEALLDEVARGRGLVVPWCPQAAVLKHAAVGLFVSHCGWNSLLEATAAGQPVLAWPCHGEQTTNCRQLCEVWGNGAQLPREVESGAVARLVREMMVGDLGKEKRAKAAEWKAAAEAAARKGGASWRNVERVVNDLLLVGGKQ
What is the function of this protein?
Involved in the biosynthesis of the cyanogenic glucoside dhurrin.  Prevents the dissociation and release of toxic hydrogen cyanide.  Mandelonitrile, p-hydroxymandelonitrile, benzyl alcohol, benzoic acid and geraniol, but not hydroquinone(1,4-benzenediol), alpha-terpinol, linalool or farnesol are utilized as acceptor substrates.  UDP-glucose, but not UDP-xylose or UDP-glucuronic acid can be used as sugar donor.
What are the official names of this protein?
Cyanohydrin beta-glucosyltransferase, UDP-glucose-p-hydroxymandelonitrile glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the presence of CYP79A1 and CYP71E1, moves toward the surface of the ER membranes in order to form a metabolon.
Protein: RIPL1_BOVIN
Sequence: MEEDRGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLIPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVSFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGELNQNGEEEPVAELGGEECVSEAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENQIPQPPPIAHPRMSPQPESGIKRLFSFFSRDKKRLANTQRNVRIHETFGQWANCHRDDGYTEQGQEALQHL
What is the function of this protein?
Plays a role in the regulation of cell shape and polarity (By similarity).  Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity).  Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity).  Competes with SIAH1 for binding GAPDH (By similarity).  Does not regulate lysosomal morphology and distribution (By similarity).  Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (By similarity).
What are the official names of this protein?
RILP-like protein 1, Rab-interacting lysosomal-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the RILPL family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
Protein: TRUB_CORA7
Sequence: MTDPLERSGLVVVDKPAGMTSHDVVGKLRRFFRTRKVGHAGTLDPMATGVLVVGIERGTKFLAHMVASTKAYDATIRLGTATHTDDAEGEATWGEPATAVEDSAIAREIAALTGDIMQRPAAVSAIKVDGKRAHERVRAGEEVELPARPVTVSRFDILATRREGEFIDLDVSVACSSGTYIRSLARDLGEALGVGGHLTALRRTEVGPFRLDDAHPLDALEDSPELSLSLDEALARSYPVLEVTDEEAQALAMGKWLEPRGLKGTYAAVDPQGRSIALIQEKGKRLATVFVARPSTL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FLP_STAAR
Sequence: MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKAFTGLAILKLAQEGRLNLNDDVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDSVTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQNNNKSKHDAIGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDEHLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKDQFNIVTVLMTTLILLAFIFSAYRAWQMRHGKIILRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTAFIALFSMLITLLLILHTTTIKKP
What is the function of this protein?
Its precise function is unknown.  Has no penicillin-binding activity and is not involved in methicillin resistance (By similarity).
What are the official names of this protein?
Protein flp, FmtA-like protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10_CITK8
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTPFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MIAB_LAWIP
Sequence: MLQRNFHIITFGCQMNTNDSFWLSCSLQKKGFQEVSLEDASIIIINTCSVREKPEQKVYSILGKIRHATKNNPDSFVVIAGCVAQQLGATFFEKFPQVRLVSGSDGIAMAPDAIERLYAEPDLKLNLTDFSEYYPEREYAFSKLTLSNNNTLALMAYVNIMQGCDNYCTYCIVPYTRGKQKSRSVQAIVEECQQLIDSGVKEIVLLGQNVNAYGLDKDKNSPANGVNFAMLVHTIASLPGLERLRFFSAHPKEFSSELIDLFGEFSTLCPRLHLPLQSGSDKILRRMGRKYSMDEYISIITKLKKVRPDIALSTDFIVGFPGETEEDFLQTLQSINTIKFMSSFSFCYSDRPGTRSSTFSNKVDHEVKIKRLEQLQATQLEHSTSWLKSRVGVETTVLLEKVSRKKAEDNNSWQGRDPWGNVVNVILPQSTNISNTLLPVRIIASKKHSLVAEPLII
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.