PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_CAMJJ
Sequence: MKIIARNKKALFDYSIIERFEAGIVLKGSEVVALRAGRANLKDSFVRIIKNEIFLLNSHISLLHTTHSFYKHEERGARKLLMHRKQIDKLLGKVSIEGYTIVALDLYFNTKNKVKATLALAKGKNLHDKRETLKKKQADLEARAAMKNYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IL34_RAT
Sequence: MPWGLAWLYCLGILLDVALGNENLEIWTLAQDKECDLTGYLRGKLQYKNRLQYMKHYFPINYRIAVPYEGVLRVANITRLKAHVSERELRYLWVLVSLNATESVLDVLLEGHPSWKYLQEVQTLLENVQRSLMDVEIGPHVEAVLSLLSTPGLSLKLVRPKALLDNCFRVMELLYCSCCKQSPILKWQDCELPRLHPHSPESLMQCAATNVYPLPRQPPTSLPRSPSSNHGPLP
What is the function of this protein?
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages.  Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes.  Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption.  Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity).
What are the official names of this protein?
Interleukin-34, IL-34.
What is the protein family that this protein belongs to?
Belongs to the IL-34 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COS7_YEAST
Sequence: MKENEVKDEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQLIQFCKEITENTPSSDPHDWEVVVANLNSYLYENKAWNTKNFFFNATDCEKMFRTTVLEPFSLKKDKAAKVKSFKDSVPYIEEALQVYATGFDKQWKLFITEKSWSPVGLEDVQLPKDIHRSKLTWFLKRIFTIYSLPLWLAFLNCICVSQHFCLAFRILCPGLFFLMMVWLFQNMRTTALLVKMEHKMQFLLTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDGIDCEWFFSHFFYRLLSAKKSMWLLPLNVELWPYIKEAQLSRNEESLMKK
What are the official names of this protein?
Protein COS7.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVB_ORITI
Sequence: MKNQLLDAKVASEEQETVLRPSLLNDFTGQNQMKSNLKIFITSSIERDESLDHTLLHGPPGLGKTTIAQIIAKEKNVNLKSTAGPILSKAADLAAILTNLQKNDVLFIDEIHRLNIHVEEILYSAMEDFSLDIMIGEGPSARSVKIYLPKFTLIGATTRLGLISKPLCDRFGIHLKLNFYSCEELTKIVERGAKVLNVALDTNAAIEIANRSRGTPRIALRLLKRVRDFGIYQNINPLNQQITDYALNQLGIDKLGLDSSDHKYLRFIAENYDGGPVGIDTIAAALSEQRDTIEEMIEPYLIQIGFVQRTQRGRVITANALKHLH
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YTM1_MALGO
Sequence: MSDRPDRVHDQAASSSRDSMTSTPSISSSNAPATVPIRLRTSLPGCSIPYVPYMVPVTWRRSQLSTLVNKVLATAQGAGHEEASYKAVPFDFIVDGSLLRCSLDEYLEQRGQSAETTLELEYIRSTLPPAFKDAARQDDWVSSVDARHAHRILTASYDGIVRIFDSESLATSPPQSYTPAYASNVSLTSAKWLRNTADAIVTGSMSGTVAVWRVPGTETKSVPVLQAAELEHHTSPVSSIDVAVAATNASAERATIVSAGWDGSIALWDVPADARFETQEETGGAPGKKRRKQHGSDARPISSAIITPPPLMVLHHVTPSLGATAARALNTAPTPGPNARTIAALGDGDQRIWSAAWDGTVKYWDVVAGGGLAGRKQTDKVPLCLDPLQSLSLSSFTTPQLVCGHMDHSLALYDFRDAVSNAALAMSGAHAAPVSAVKVHPVSAHLFASGAYDGRIKVWDVRSPKQALFALSEPVSTSSKSSHMASSKQPRTKVLGLDWTPDGNALVSGGEDCRVCLYQGQAIGIEHV
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: YBEY_BACCR
Sequence: MSLLIDFIDETEEVKEEYMSLIREVLEKAAQMENIEDGAEVSVTFVDNERIREINRDYRDKDQPTDVISFAMEEMGEGEMEIVGAEMPRMLGDLIISIPRAKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGRQKEILEAFGLGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_PROMM
Sequence: MTATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLSDRDLKLAEAINLLEPG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: SYA_LEVBA
Sequence: MKELTSSQIRQMYLDFFKSKGHTIEPSASLVPKDDPSLLWINSGVATMKKYFSGQVVPENPRLTSSQKSIRTNDIENVGKTARHHTLFEMLGNFSVGDYFKKEAIAWAWELLTSPDWFGWDPDKLYMTVYPKDTDAKDAWEAVGVAPDHIIAVEDNFWDIGEGPSGPDSEIFYDRGEAFNNLAADDPENYPGGENERYLEVWNIVFSQFNHEPDGTYKPLPRKNIDTGMGLERVVSIFQNAKTNFETDLFMPLIEKTAALSAGKHYGANAEDDISFKVIADHARAITFAIGDGALPGNEGRGYVIRRLIRRAIVNGQKLGIEGAFLDQLVPVVGQIMQAYYPEVLEQSDYIAKVVRSEEDRFGETLTDGLNLLNSLIADLKQQGGNQIAGADAFKLYDTYGFPVELTEEYADDQGITVDEAGFKAEMQKQKDRARNARGKQKAMGLQHDLLINVKTPSEYVGYTQLATTSKLTVLVAGDELVDHVTSGTAEAMFDVTPFYAEMGGQVADKGDILDEAGHVVAHVADVQHAPNGQNLHTLTVVAPMETGATYQLKVDTIFHSKVEKNHTATHLLDKALREVFGEHTQQAGSLVEGDYLRFDFTHFGQVDPADLAKAEALVNQKIFEELPVTTVETDIESAKKMGAIALFSEKYGKVVRVVSAGDFVTEFCGGNHVKNTNEIGLFKITSESGVGAGVRRIEAVTSAAAYAYLHDHDEILNAVGADLKVTQVDEIEQKVQALQAQVKALEQQQATLEGKLASQEAGAVFDHVTTAGNYQLISGTVQVSKMDQLRALADTWRDQALSDVLVLGAEVNGKANLIVAVSADKQKQVKAGDLIKAISPKINGGGGGRPNLAQAGGKNPAGLPDAMTAAADWLAEQK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_BIFAA
Sequence: MVNAIEAFDAKHMKPAEEIPAFRPGDTVEVNVKIKEGNNSRIQAFTGVVIARQGGGVRETFVVRKISFGTGVERRFPLHSPAIDSIKVVRKGRVRRAKLYYLRNLRGKAARIVERRDNSEK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DAPA_LEUMM
Sequence: MYEGINLITAIITPFTVNDEIDYESLEKLIEHLLNHGSQGFVIAGTTGESPTLSFEEKVELTRFIAKQVGNRALLIANAGSNNTKESVEAAKALSKIEHINGILAVTPYYNKPSQAGMIAHFKAIADASEKPVMLYNIPGRTVVGLTVDSVIELAQHPNINAIKETTSTEFVEAEVEGATGFAVYTGEDAMTLSAYTVGGAGTISVASHLYGDEMSELFSAMNAGNWREAGRLQRYLTPRMNALFAYPSPTPVKTKLAEKGFVREAVRLPLIPLSDAEKLHLNELLEK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y233_GEOSL
Sequence: MEILLNDVEVRVLGCLIEKELATPEYYPLTLNSLTTACNQKSNRDPVMALEESEVVRALDGLKMKHVAIQAADSGRVPRYRHILSERLRFSPAELAILAELLLRGPQTLGELRTRAERMHPFADLAAVEQVLGELAERTPPLVMRLPRQPGRKESRFAHLLAGEPDLSAEERTAPPEGARLQVMAENERIAALELEVATLRAEVGELRQVMEEFRSQFE
What are the official names of this protein?
UPF0502 protein GSU0233.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: MURD_BACC3
Sequence: MKTVTEFQNKNILVLGIAKSGYAAATLLQKLGANVIVNDGKPLAENVLAAELQAKGMDVVCGGHPLELLERNISLVVKNPGIPYSNPILVAAKEKQIPIVTEVELAYRISEAPFVGITGSNGKTTTTMLTFEMLKEGQKHPVIAGNIGTVACEVAQDAKENEVVVTELSSFQLMGVELFQPKIAAFLNLFEAHLDYHGTKKEYGLAKANIFKNQTENDYSVINADDADVMALSAYSKGQKVLFSTTKEIEDGACIKDNALYFKAEKVVEVDDIVLPGQHNLENILAAMSIAKLLGVSNEAITAVLKRFTGVKHRLEYVTTINNRKFYNDSKATNMLATEKALSAFTQPTVLLAGGLDRGNEFDDLIPYFKNVKAIVTFGQTAPKLVRAAEKAGLETIESVDTLDEAVVKAYAHSTDGDVILLSPACASWDQFKTFEERGDIFIQAVHKLI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BDEBA
Sequence: MLESKMKLVGKIREAHGLKGDLYVLVFSGEIAWAKRMKTFGLKAKDSDEIKTFTVERTKPFKKGLIVKAAEVADRTAAEGLEHMEFFIDDELMVSKPGETIFLSEIKNFKLKNPEQTVLGEIVGFSSNGVQDLLVVETTDGKTAEVPFVDAFIKKIDFKHQAVVMDLPEGLFDIENA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_QUERU
Sequence: MSPQTETKASVGFKAGVKDYKLTYHTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTSYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPOR2_IPOBA
Sequence: MKAFALFFVLSLYLLPNPTHSKFNPIRLRPAHETASSETPVLDINGDEVRAGENYYMVSAIWGAGGGGLRLVRLDSSSNECASDVIVSRSDFDNGDPITITPADPEATVVMPSTYQTFRFNIATNKLCVNNVNWGIKHDSESGQYFVKAGEFVSDNSNQFKIEVVNDNLNAYKISYCQFGTEKCFNVGRYYDPLTRATRLALSNIPFVFVIKPTDM
What is the function of this protein?
Major tuberous root protein.
What are the official names of this protein?
Sporamin B, Clone PIM0535.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NADK_PELPB
Sequence: MKFAIVVNVTRQNALDLARNLALWLDERKVAYIFESLSAEKLQTDNSAPIEELNKHCDAFISLGGDGTLLFTSHYAVTKPVIGVNVGYLGFLTEFTQAEMFTAIERVLNGSNTIHTRSQLDATVLIDNEVQHLRALNDVVIEKGAYPRIPTFIIKLDGELLSSYRADGIIIATSTGSTAYSMSAGGPIIAPKSSVFVITPICPHMLTVRPIVISDEKIIEVSVDAPDGSFPLNCDGNLKKMLDPQESITVRKSTVAINLVANENRDYCEILRTKLLWGREHNFGTIDS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA11_MOUSE
Sequence: MPHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPCVSAQNSGIPLLSCAVP
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Histone deacetylase 11, HD11.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPR_MACMU
Sequence: MICQKFCVVLLHWEFICVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNLNGHYETAVEFNSSDTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSSVFQQMGANWNIQCWLKGDLKLFICYVESLFKNPFKNYKHKVHLLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHERCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLRMEITDDGNLKISWSSPPLVPFPLQYEVKYSENSTTVIREADKIVSATSLLVDGILPGSSYEVQVRGKRLDGPGIWSDWSTPHVFTTQDVIYFPPKILTSVGSNVSFHCIYKNENKIVSSKKIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGHLTKMTCRWSTNTIQSLAGSTLQLRYRRSSLYCFDIPSIHPISKPKDCYLQSDGFYECVFQPIFLLSGYTMWIRINHPLGSLDSPPTCVLPDSVVKPLPPSSVKAEIIKNIGLLKISWEKPVFPENNLQFQIRYGLSGKEIQWKMYDVYDAKSKSVSLPVPDFCAVYAVQVRCKRSDGLGLWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNESLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVILSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFAQDNTEKHQNDAGLYVIVPVIISSSILLLGTLLILHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPETISEDISVDTSWKNKDEMVPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTCEDESQRQPFVKYATLISNSKPSETDEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQRPNIILPHLTFSEGLDELLRLEGNFPEENNDEKSIYYLGVTSIKKRESGVLLTDKSRVLCPFPAPCLFTDIRVLQDSCSHFVENNFNLGTSSKKTFASYMPQFQTCSTQTHKIMENKMCDLTV
What is the function of this protein?
May transport LEP across the blood-brain barrier.  Binds LEP and mediates LEP endocytosis.  Does not induce phosphorylation of and activate STAT3.
What are the official names of this protein?
Leptin receptor, LEP-R, OB receptor, OB-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane.
Protein: ARGJ_PSEPK
Sequence: MAVGLGPLPTLHPVPGFELGIASAGIKRPGRKDVVVMRCAEGSSVAGVFTLNAFCAAPVILSKQRVQGTVRYLLTNTGNANAGTGAPGLAAAERTCAKLAELAGVPAESVLPFSTGVIGEPLPVEKIEGALQAALDNLSENNWAEAATGIMTTDTLPKGASRQFQHDGVTVTVTGISKGAGMIRPNMATMLGYIATDAKVAPKVLKDLMLDGANKSFNRITIDGDTSTNDCCMLIATGKADLPEVTEASGALFEALKKAVFEVCMEVAQAIVRDGEGATKFVTVQVNGGGNHQECLDVGYAVAHSPLIKTALFASDPNWGRILAAVGRAGVPELDVSLIDVYLDSVCIASKGGRSPSYTEAQGSAVMAQEEITIRIELGRGQCSETIWTTDLSHEYVKINAEYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRD28_CAEEL
Sequence: MLYQLLHTVLSVVGVSLNAFMMYLALTKSPKIMLPCSAIITIKTFTDILTSAMSFFVMQRIVTDGSSILVIPTGPCTHLGPTACYIGHMFMLCFLECNLIWMISSYIFRYYILYVRDPSIKSLVFVAICLSIPSFIHMATWISNYDPTVAIAIPENVGIESRDMVLGGTIVTWSALTLIIQLFITSILVLIAYAWIRNTLLSFAVKMGSDKNDVKKLNTRLVKVINFQVFLPSFIFLGVFVFVGMFTQLIDPKISQYLVSVIFMFSPICSPFSYILFVPHYLNVILGNKKVSEAKSTTEGCTFRHVNMAASTSNTPECSA
What are the official names of this protein?
Serpentine receptor class delta-28, Protein srd-28.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSRP1_RAT
Sequence: MSSAAVSKYVNDMWPGSPQEKASPSTSGSGRSSRLSSRSRSRSSSRSSRPHSRSSSRSSSRSHSRPRRSRRSRSRSRSRRRHQRKYRRYSRSYSRSRSRSRGHRYYRDSRYEQPRRYYQSPSPYRSRSRSRSRGRSHHRRSYYAITRGRRYYGFGRTVYPEDRPRWRERSRTRSRSRSRTPFRLSEKDRMELLEIAKANAAKALGTANFDLPASLRAKEASQGAVSCSGPKTEHSEKQTEVGTKNASEKSAAAQRNIAFSSNNSVAKPLEKTTKAAVEETSSGSPKIDKKKSPYGLWIPV
What is the function of this protein?
Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.
What are the official names of this protein?
Arginine/serine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the RSRP family.
Protein: CSPLD_ORYSJ
Sequence: MSSYMEAAAAARAAEAKTEGLLRGACALLAAAAALLVGLNTQTETVLFIRKKATVKDVQALWVLAMAAAAAAGYHLLQLLRCFYLSRFADGKPCRHRRAIAWLCFLLDKGCAYITFATTVAAAQACVVALYGTHALQWTKLCNIYTRFCEQVAGSLVCAMLAAVGTALLSVVSARNLFRLYPSMLSPPPSSFVG
What are the official names of this protein?
CASP-like protein 2C1, OsCASPL2C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_PETMO
Sequence: MISFNLTSIVNLVGFLAFMFLMYRLLYKPYFDMTDKRKKEVEKNLNEAEKLRLEAQLKKEELDKQLSEADEKRREILSEADEQAKSIIKAAQGEAQEQRKFILDKAEKEAEEIKESAARELQSRIVSLAVTISSMILKEQIDKKKNEELIRRAINSLKDKGEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: VPS29_XENLA
Sequence: MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESFDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQLDVDILISGHTQKFEAFEHENKFYINPGSATGAYNALENNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity).  Acts also as component of the retriever complex.  The retriever complex is an heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrins.  In the endosomes, retriever complex drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 29, Vesicle protein sorting 29.
What is the protein family that this protein belongs to?
Belongs to the VPS29 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: DER_DESHD
Sequence: MSKPVVAIVGRPNVGKSTLFNRLAGGLVAIVENRPGVTRDRLYRDSEWLGRKFTIIDTGGIEFVNENTSISAQMRRQAEIAIEEADVIVFVIDAQISPTPDDDMIAQTLRRSGKPVILAANKVENFAKTELYEFYNLGLGEPVPISAVHGMNIGDLLDEVVSHFPEDIEEEVDPDTIRIAVVGRPNVGKSSLVNTLLGEERVIVSNIPGTTRDAIDSAFEHEGKHYIIIDTAGMRRKGRIEELTEQYSVSRSLRAVDRSDVILMLLDAGEGVTEQDKKIAGYAHEAGKGIVLVVNKWDLIEKDDKTMNRFEKDIREELGFMQYAPTLFISAKTGQRVTKLLDLVDFVAEQNSTRVATATLNTLVREWVHLNPPPTDKGRRLKVLYATQVGVKPPTFVFFVNDHELMHFSYRRYLENQLRSSFGFEGSPIRMIVRQKDEERE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RFS1_CAEBR
Sequence: MDSSKITFEYETAYELLVRLGADGLFLHTSLPTLNKVLELVPGKCYELDGDIGSGKTQLCYSLAAKLLLTKKTAKIGWISAVPLRTDHLSQHISSTDADETSHLLDRIVCKRVEMVSELRDSLNALCETINMQLVIVENIDAILHDTAYDREMGRNVQIDISERLRKLTRSGITVMVTNHITYWRGYPAPALGNFWASQIENRFFVERRSEESNVRSVSTMRGGNEKTIRVDFEISDGGLKAVV
What is the function of this protein?
Has a role in the homologous recombination repair (HRR) of genomic DNA during meiosis.  Required for rad-51 recruitment onto ssDNA gaps generated at stalled replication fork barriers (By similarity).
What are the official names of this protein?
RAD51-like protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PVK1_PERRU
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PerRu-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.