PharMolix/UniProtQA huggingface dataset:
Protein: CH60_HELVI
Sequence: AKDVRFGADVRALMLQGVDVLADA
What is the function of this protein?
Implicated in mitochondrial protein import and macromolecular assembly.  May facilitate the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity).
What are the official names of this protein?
60 kDa chaperonin, mitochondrial, P60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ALE1_STACP
Sequence: MDTNRKFTLVKSLSIGLGTFLVGSVFLTVNDEASASTKVDAPKVEQEAPAKADAPKVEQEAPAKADAPKVEQEAPAKVDAPKVEQEAPAKVDAPKVEQEAPAKADAPKVEQKRTFVREAAQSNHSASWLNNYKKGYGYGPYPLGINGGNHYGVDFFMNVGTPVRAISDGKIVEAGWTNYGGGNEIGLVENDGVHRQWYMHLSKFNVKVGDRVKAGQIIGWSGSTGYSTAPHLHFQRMTNSFSNNTAQDPMPFLKSAGYGSNSTSSSNNNGYKTNKYGTLYKSESASFTANTDIITRLTGPFRSMPQSGVLRKGLTIKYDEVMKQDGHVWVGYNTNSGKRVYLPVRTWNESTGELGPLWGTIK
What is the function of this protein?
Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan.
What are the official names of this protein?
Glycyl-glycine endopeptidase ALE-1, Staphylolytic enzyme ALE-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_METFK
Sequence: MAAKQVIFGDDARAKIVNGVNILANAVKVTLGPKGRNVVLERSFGSPTVTKDGVSVAKEIELSDKLENMGAQLVKEVASKTNDNAGDGTTTATVLAQAIVREGFKYVAAGFNPTDLKRGIDKAVAEIVNEIKAIAKPTTTSKEIAQVGSISANSDADIGQIIADAMDKVGKEGVITVEDGSGLQNELDVVEGMQFDRGYLSPYFINNPERQIALLENPFVLLYDKKISNIRDLLPTLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKAVAVKAPGFGDRRKAMLEDIAILTGGTVIAEEVGLSLEKVTLENLGQAKRVEIGKENTTIIDGAGSENNIKVRIDQIKKQIEDATSDYDREKLQERVAKLAGGVAVIKVGAATETEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRARSSIKELKGDNPDQDAGIKIVLRAIEEPLRQIVANAGDEPSVVVNKVLEGTGNYGYNASNGTYGDLVELGVLDPAKVTRSALQNAASVASLILTTDALVAELPKEEAAPAMPDAGGMGGMGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM2L2_MACLB
Sequence: MIQVLLVTICLAVFPYQGSSKTLKSGNVNDYEVVNPQAVTGLPKGAVKQPEKKYEDTMQYEFEVNGEPVVLHLEKNRGLFSKDYSETHYSPDGREITTNPAVEDHCYYHGRIQNDADSTASISACNGLKGYFTLRGETYLIEPLKLPDSEAHAVYKYENIEKEDEAPKMCGVTQTNWASDEPIKKASQLNLTPEQQRFEPRYIELVIVADHAMVTKYNGDLAAITTWVHQLVNNINGFYRDLNVHITLSAVEVWTNGDLINVQPAASVTLNLFGEWRERDLLNRRMHDHAQLLTGIDLDDNIIGLAYDDSMCDPRYSVGIVQDHSAIIRLVAVTMAHELGHNLGMNHDGDQCNCGANGCVMSVVLIEQRSYQFSDCSKNKYQTYLTNRNPQCILNQPLRTDTVSTPVSGNELLQNSGNPCCDPVTCQPRRGEHCVSGKCCRNCKFLRAGTVCKRAVGDDMDDYCTGISSDCPRNPYKD
What is the function of this protein?
Poor inhibitor of platelet aggregation.  The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1.  Inhibition on alpha-2b/beta-3 (ITGA2B/ITGB3) is low (By similarity).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LCSS_PURLI
Sequence: MTLYFAYPNAESGDCKCLGLIFFVKDYYGEKVFPPIGCVGITQFENQASKTNYFSNVDKARSLQKRFMEEAGVDVVGRVKALLQSIVPPGLPVRLAQEDGKSYFAGLLRLINSSALIHADYGPFDGPGWEIGAIKAQLTWNILLKEVRGGESVVYNRFWKGKEDDDKYRDVTKSYGYSRDVIDGCESKKIAPIVGQIALFNPRNFHEVLAIENPEKVSRYTFSSFIGYLPPTAPEGPAIILWS
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic (PubMed:27416025).  The function of lcsS within the leucinostatins biosynthesis has not been identified yet (Probable).
What are the official names of this protein?
Leucinostatins biosynthesis cluster protein S.
Protein: TRPB1_METTH
Sequence: MIMDGKFGKYGGIFVPELLIPALEELERAFLHYRDDRKFMAELEYHLREYAGKPTGLYYARNLSEKLGCRVYLKREDMLHTGAHKINNTIGQALLARYMGKTRIIAETGAGQHGIATAAAGALFGMDVDIYMGTEDVERQKLNVFRMEVSGAEVIPVDSGSRTLKDAINEAMRDWISNVDDTHYLIGSTMGPHPYPTMVKHFQSVIGREAREQILEVEGELPDTVIACVGGGSNAIGIFSAFMDDDVELIGAEGGGEGIESGNHGATLSAGSEGILHGSLSYVLQDGDGQISEAHSVSAGLDYPGVGPEHAHLMDTGRARYEPVTDTEALRGFRLLSRYEGIMPALESAHAIACLERYAEKPENRGKTVIVNLSGRGDKDMFMVAGLLGVGV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LSOA_ECO57
Sequence: MAQNPFKALNINIDKIESALTQNGVTNYSSNVKNERETHISGTYKGIDFLIKLMPSGGNTTIGRASGQNNTYFDEIALIIKENCLYSDTKNFEYTIPKFSDDDRANLFEFLSEEGITITEDNNNDPNCKHQYIMTTSNGDRVRAKIYKRGSIQFQGKYLQIASLINDFMCSILNMKEIVEQKNKEFNVDIKKETIESELHSKLPKSIDKIHEDIKKQLSCSLIMKKIDVEMEDYSTYCFSALRAIEGFIYQILNDVCNPSSSKNLGEYFTENKPKYIIREIHQETINGEIAEVLCECYTYWHENRHGLFHMKPGIADTKTINKLESIAIIDTVCQLIDGGVARLKL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  A stable (half-life over 20 minutes) endoribonuclease that degrades mRNA.  Degradation may be translation-stimulated.  Overexpression in the absence of cognate antitoxin LsoB causes retarded growth and mRNA degradation, this effect is mitigated upon coexpression with antitoxin LsoB or enterobacteria phage T4 Dmd.  Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction.
What are the official names of this protein?
mRNA endoribonuclease LsoA, Toxin LsoA.
Protein: MURG_NITHX
Sequence: MTTTPLILLAAGGTGGHLFPAEALGVELMKRDLRVRLVTDSRALRYSGLFSKDMTDVVPSETVRGRSPLALARTGLMLATGTVVALNLMRRLKPAAVIGFGGYPTLPPLIAARLKGIPTVIHDANAVMGRANRLLSRRVNAIATSLPGVLDKEPSLIGKTTTTGTPMRPAILAASTVPFATPGSDGPLRVLVVGGSQGARVMSDIVPGAIEKLGSPLWQRLVLTQQVRDEDMARVRAVYERLRINAELAPFFADLPSRLASSHIIVSRSGAGTVAELGAIGRPSILVPLPGAIDQDQFANAGVLADVGGAIRIVQSDFTPDRLAAELSALAADPARLAAMAAAARTVGRLDAAERLADLVMKVARLDSPA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARO1_SCLSC
Sequence: MGSTTFENPTRIEILGKEDIIVDFDIWRNFVAEDLLSDLPSSTYVLITDTNLSPLYVPAFQQSFEALAAKSSSTPRLLTYEIPPGENSKSRETKAEIEDWMLSHQCTRDSVIIALGGGVIGDMIGYVAATFMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPLGKNLVGAFWQPQRIYIDLRFLETLPVREFINGMAEVVKTAAIWDEAEFSALEDNANLIMTTIRAKNTDCSTRLGPIRDILKRIVLGSAKTKADVVSADEREGGLRNILNFGHSIGHAFEAILTPQVLHGEAVAIGMVKEAELARHLGVLKPGAVARLVKCIASYGLPTSLADKRIQKLTAGKLCPVDVLLEKMGVDKKNDGRKKKIVLLSAIGKTYEPKASVVEDRSIRVVLSDSVEVRPSVPETLNVEVTPPGSKSISNRALVLAALGTGPCRIKNLLHSDDVEFMLTSIGKLGGATYAWEDAGEVLCVQGKGGDLHASPTELYIGNAGTASRFLTTVVSLCKPSASTKSTILTGNARMKVRPIGPLVDSLRANGVDIEYLEKEHSLPLNVAASGGFTGGDINLAATVSSQYVSSLLMCAPYAKNPVTLRLVGGKPISQLYIDMTTAMMAAFGIHVVRSQTGEHTYHIPQGVYKNPEEYVVESDASSATYPLAVAATSGTTCTIPNIGCKSIQGDARFAIDVLKPTGCKVVQTDYSTTVTGPPIGSLQAIEEVDMEPMTDAFLTASVLGAVAKGTTKIRGIANQRVKECNRIKAMKDELAKFGVTCRELEDGIEVDGVPIKDLKHPAEGIHCYDDHRVAMSFSVLSVAASQPVLIEERECVGKTWPGWWDILSKSFQVELAGKEVKATHSKKIGIPTLPDKSIFIIGMRGAGKTTAGAWAAKILGRPYKDLDVELERISGMSIPDMVRSKGWDFFRAAELDLLKHCLTDQPEKHVFACGGGVVEMPEARELLINFHKSGGIVLLVHRDTEQVMDYLRIDKTRPAYVEDMMGVYSRRKPWFNECSNFQYHSKGSGASALSVAEQDFARFLHHISGKSLHFDEMRNKPQSFFVSLTMPDISGAAYILPSVAVGSDAVEVRVDLLEDPSSTNGIPGTDFLSVQIAHLRSVVHLPVIFTVRTVSQGGRFPDAAHEEALKLYKLAVKMGIEYIDLEIAFPDELLQEVTEAKGFSRIIASHHDPQGTLSWKNGGWFQHYNRALQYGDIIKLVGSAKSIEDNFALAKFKKTMAAAHDTPLIAINMGVTGKLSRVLNGFMTPVSHPSLPFKAAPGQLSAAEIRSTLSTLGEIEPKSFYLFGTPISQSRSPALHNTLFKQTGLPHRYSRLETDRVADVQDVIRAPDFGGASVTIPLKLDIIPLLDSVTDAVKVIGAVNTIIPTPDNPPRLVGENTDWLGMTHSLMSASHTPSPVDSPSPALVIGAGGTARAAIYALHSLGHSPIYMVARTPSKLDTLINSFPSSFNIIPLPSTTSATELTTPPAVAISTIPADRPIESNMRETLAVLLRHEKKDEGKQRTLLEMAYKPSQTPLMRMAEDAGWVAIPGLEVLSAQGWYQVSLFPFHLLVCYEVIFLNGFTKIYRLVSKMDKHPTFVC
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_SHEB2
Sequence: MTESRIDFRRAKFLISAPDIAHLDQYLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFELDAQRRLVDLPGYGFAQVPLALKNKWQQALGEYLQKRACLSGVVVLMDIRHPLKDLDMQMIEWAVASEIPVLALLTKSDKLAQSAKMKTVNEVRLALSEFGDWVQVEPFSSLKGTGKPKVLAILNEWCHPQWLTDELDAANNAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS16_THEM4
Sequence: MVRIRLTRMGKKKQPFYRIVVVDQRKRRDGAYIESLGYYDPIKDPYILNVDVDKAVDWILKGAQPSQTVKNLLRKAGVFKKVDEIKRTKKKEENQ
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: METE_HAEIE
Sequence: MTTSHILGFPRVGAKRELKFAQERYWRKELAEQDLLDLAKALREKNWKHQAAANADFVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLTLDQYFQLARGNKDQFAIEMTKWFDTNYHYLVPEFQKSTAFKANPAHYVNQIREAKALGLNFKPVIVGPLTFLWLGKEKGEAFNRFDLLNQLVPVYVEILNALVAEGAEWIQIDEPALALDLPAEWVEAYKSVYAELSKVNAKLLLATYFGSVAEHAELLKALPVAGLHLDLVRAPEQLAAFEDYSKVLSAGVIEGRNIWRANLNKVLDVLEPLKAKLGERLWIAPSCSLLHTPFDLEVEVQLKEKNTALYSWLSFTLQKVEELNVLKQALNNGRASVQAALDASQAAADARATSKEIHRPEVAERLANLPKGADQRKSPFAERIVKQNAWLNLPLLPTTNIGSFPQTTEIRHARASFKKGELSLADYEAAMKKEIEYVVRRQEELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVTRPEPMTVRWSQYAQSLTNRVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVLDLEAAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGVQDDTQIHTHMCYSEFNDILPAIAALDADVITIETSRSDMELLTAFADFKYPNDIGPGVYDIHSPRVPTAAEVEHLLRKALNVIPKERLWVNPDCGLKTRGWTETIDQLKVMVDVTKKLRAELA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RLMN_GEOSL
Sequence: MDTMIDIKGLSIDELERFLLGKGKERYRARQIFKWLYQRGATSFAEMTDLAKELRRDLEETARISTLSPEALEISRDGTRKYLFRLDDGCSVESVLIPEEDRNTLCISSQVGCAMACEFCLTGTFRLTRNLTTAEIVNQVCAVQRDVPVRNIVFMGMGEPLANLDNVIRALQIMLHDDGLQFSTRRITVSTAGLVPEMERLGRSVTVNLAVSLNATTDELRDRIMPINRKYPLAVLLDACRRFPLPGRRKITIEYVLLGGVNDTLDDAKRLVRLLSDIPSKINLIPFNEHEGCSFRSPSQDAIDRFHRYLLDKHFTVITRSSRGADISAACGQLKGKLDALKPSGAGKQIEVSDSTNEVT
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CLOD6
Sequence: MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMSFHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESLSMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDHHKIESIFKAFARALKEGSEIVSNEIASSKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACH1_ASHGO
Sequence: MTVSQLLKQRVRYAPYLSKVRRAEELLPLFKHGQYIGWSGFTGVGAPKVIPTALADHVEKNGLQGQLAFNLFVGASAGPEENRWADLDMILRRAPHQVGKPIARAINDGRIKFFDKHLSMFPQDLTYGYYTRERTDGKILDYAIVEATAIKEDGSIVLGPSVGGSPEFMSAADKLIVEVNTATPSFEGLHDIDMPVLPPHRVPYPYTRVDERSGLDAVPVDPARVVALVESTERDKVGPNTPSDEGSRAIAGHLVEFFENEVRHGRLPANLLPLQSGIGNIANAVIEGLAGASFRNLTVWTEVLQDSFLDLFENGSLEFATATSIRLTEAGFEKFFANWDEYSSKLCLRSQVVSNSPEMIRRLGVIAMNTPVEVDIYAHANSTNVSGSRMLNGLGGSADFLRNAKLSIMHAPSARPSKTDPTGISTIVPMASHVDQTEHDLDVLVTDQGLADLRGLCPRERAREIIRQCAHPDYKPILTDYLDRAEHYAQRSRSMHEPHILQQALRFHTHLAEKGTMKVPSWD
What is the function of this protein?
Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.
What are the official names of this protein?
Acetyl-CoA hydrolase, Acetyl-CoA deacylase, Acetyl-CoA acylase.
What is the protein family that this protein belongs to?
Belongs to the acetyl-CoA hydrolase/transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASP3_STAA8
Sequence: MLKNKTFKVTWNYISQTTFMYGSKVSFSNGEVTFINPLMPSGLPIHEWLMLKQFSKYKSAPSLPILRRGQHYKLHFDFDATPAGSVYFIIIFYNKNGTKLSTEIVKSNSITIQYPDEAYAYKIKMMNAASTSLIFRCLTITEMTHQYDLEYKSMRVTKIGDDQYGNDMINVIIAEPSDTYPTISNDFLKLFGHVWLVERWMDDNIEGNIKQLKNDLQSQDTLKAINLISYGSKSNVFATYVAQHLGCKVYRTSHEDDDLKGWLTEHVPGNHELKDTNVEVYFKEEQDKHLNYMSRLMNPVRFLDYLDVSKLNGGEVNET
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon.
What are the official names of this protein?
Accessory Sec system protein Asp3, Accessory secretory protein Asp3.
What is the protein family that this protein belongs to?
Belongs to the accessory Sec system protein Asp3 family.
Protein: HIS82_BACCZ
Sequence: MQVKDQLSLLQPYKPGKSPEQMKEVYGDHSFVKLASNENSFGCSPRVLDELQKSWLDHALYPDGGATTLRQTIANKLHVQMEQVLCGSGLDEVIQIISRAVLKAGDNIVTAGATFPQYRHHAIIEGCEVKEVALNNGVYDLDEISSVVDNNTKIVWICNPNNPTGTYVNDRKLTQFIEGISENTLIVIDEAYYEYVTAKDFPETLPLLEKHKNILVLRTFSKAYGLASFRVGYAVGHEELIEKLNVVRLPFNVSSLAQKAATIAFGDDEFIEEIVRVNTEGLRQYESFCKENEIPFYQSQTNFIFLPVENGGEIYEACAHAGFIIRPFPNGVRITVGTREQNEGVISVLQQHFENKKRKSRDEANV
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: IF2_BURPS
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSETDKARLLDHLRKSHGATDGDKRKITLTRRHTSEIKQADATGKARTIQVEVRKKRTFVKRDDVSETGADQAQAQTDEQAEAELKRREEEARREAELLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAAQAEAAQQAAAAREQAQRAQSEPAEQSAQDEARAAAERAAQREAAKKAEDAAREAADKARAEQEEIRKRREAAEAEARAIREMMNTPRRAQVKAVEPPKPAEPPAAKAAEAKGTLHKPAKPAGEAAAARPAAKKPASGAPAPAAAPAGDRTKKPGTGKSGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGKHQDSASSFQAPTEPIVREVHVPETISVADLAHKMSIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGEIGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVESPAKGIVIEAKLDKGKGPVATVLVQSGTLSRGDVVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPGAGEEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGVVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVKQGFECGMSLKNFNDIVEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK9_SCHPO
Sequence: MQTPSSASAESEKDSGNTYVGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPNIITLYQVFRVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLSTSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSASDLIRQMLMVLPTSRIKVAEIMQHPWFIADLPTHSRLPSRTSSFSSKHRSVTFSPPDLAILFDPSITSPSSSVGQIPQPTDHSALSPSKPMSISGTESPNPDPASLCYSSYEDLYSATSWHSDMAESSGFLDPTDIPPIPSNVETLRSSLPQRHASFMNKVYNHPLSRPPAPNRLRSLRWHYGIQTAKNPIEVLRKLCEALLELGARFRPCDEESFLKENKYKVFSCITCHNSPVYLVIELFSIGPSASVIDIRFSSSDDSIKYTSSYSPMPFLEVVKQLILKIA
What are the official names of this protein?
Protein kinase domain-containing protein ppk9.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: ARNA_ECO81
Sequence: MKTVVFAYHDMGCLGIEALLSAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWMERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFMNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLNWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: GPPA_VIBC3
Sequence: MSQAVSSPLYAAIDLGSNSFHMLVVRHIDGSVQTMAKIKRKVRLAAGLDEHNALSLDAMQRGWDCLSLFAERLQDIPAENIRIVGTATLRTATNAGEFIAKANQILGHPIDVISGEEEAATIYKGVAHTSGGLGRRLVVDIGGASTELIIGEGFEAKALTSLKMGCVTWLERHFKDRQLTATNFNNAILAAKQMLDPILTQYTELGWNVCVGASGTVQALQEIMLAQGMDEVITLTKLKRLQKQAMLADHLEELDIEGLTLERALVFPSGLSILIAIFESLNIEAMTLAGGALREGLVYEMVQDLRQEDIRARTIRCVQTRYQIDSAYGDQVATLASKLLAQCGGEAWINEPQAEMLLRTAAKLHEIGLTIDFKKGGEHSAYLLQHLDLPGYTRAQKHYLGEIVRRYREQLTSLPEQYALSGTSGKRVLRLLRLAVLLSHRRSPALEPMVELSAQEDKLTLTLDGEWLAKNPLTRTELELEANRQTDIGWPLSIECH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: SATT_BOVIN
Sequence: MEKSSETNGYLDSAQEGPAAGPGEPGTTARRAGRCAGFLRRHGLVLLTVSGVVAGAGLGAALRGLQLNRTQVTYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASSLGRLGGIAIAYFGLTTLGASALAVALAFIIKPGSGSQTLQSSDLGLEDSGPPPVPKETVDSFLDLTRNLFPSNLVVAAFRTYATDYREVTYNTSAGKVTIEKIPIGTEIEGMNILGLVLFALVLGVALKKLGSEGEELIRFFNAFNEATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIMLVTSLGKYIFTSILGHFIHGGIVLPLIYFVFTRKNPFRFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVELRAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQKAMKRGEQELSEVKVEAIPNSKSEEETSPLVTHPNPTGPAASTPESKESVL
What is the function of this protein?
Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.
What are the official names of this protein?
Neutral amino acid transporter A, Solute carrier family 1 member 4.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: PGAM1_HUMAN
Sequence: MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate (PubMed:23653202).  Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate (PubMed:23653202).
What are the official names of this protein?
Phosphoglycerate mutase 1, BPG-dependent PGAM 1, Phosphoglycerate mutase isozyme B, PGAM-B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ZGPAT_DROSI
Sequence: MEEYEAQLLVVEQALENAADDAQRQELLALKNNLQELLALTRDTGDEAPTDELPQQGNDLDDELQRLKSELSALEAAGSSQTALDEERQLADLRTKYTAMVGEKCSAPHEHSWGTCYHNALICGVDDEVVINSEGVLDARLRVLFTNPTHREMLPCSYYLEGECRFDEAKCRFSHGALVTGSSIRKYNPPDFHKLSRSRPVFALLPDRLWHRGRVLCVNFVEQVCRVRLDGQDHKERERDFKFEELYPLTTDQDEDDELSSEESTSSMRDASSDEAESDMDDLEEARRARMVELSLFTYKPTDRLGAWEEFTRGIGSKLMEKMGYIHGTGLGSDGRGIVTPVSAQILPQGRSLDACMELREAANGDKDYFSVERKLKRAQRRQRKADEKAYVRESQRVDVFTFLNDRVLGPGESTQQSEQVAKKAKTNELQQHSTKTLNVETVRIADEIRRKQRDMAKVKQSLERNSGDAQLQKRLQVQMQSHKQELATLQAQERSLSKEQQTRKSKNKMFEF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK_MARMM
Sequence: MTEIRRIQDADVAGKRVLVRVDFNVPMKDGQVTDATRLEAALPTIEYLTEAGAKVVLLAHFGRPKGAVVPEMSLEAVCQPLADLLGDAVYFSTVTSGEDAVAATMDLEAGEVLLIENTRFAAGEETNDPGFAAALAELGDLYVNDAFSAAHRAHASTEGITHHLPSYAGLALQREIDHLVAALESPKRPVIALVGGAKVSTKIDLLQNLVKKVDTLFVGGGMANTLLHAQGIKVGSSLCETDLVDTARAIFAAAEESGCKLMLPTDVVLAKEFKPNPETRLAAVTDVEDNEMILDCGPATVVALGQAIDRSATLIWNGPLGAFETPPFDAATVEAAKYAARAAVEGELIAVAGGGDTVSALNQAGVSGDFTFISTAGGAFLEWMEGKTLPGIAAVMGTPELVA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.