PharMolix/UniProtQA huggingface dataset:
Protein: RF2_ECOLI
Sequence: MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (PubMed:11118225, PubMed:17932046).  Acts as a peptidyl-tRNA hydrolase (PubMed:22857598, PubMed:27934701).  In the presence of truncated mRNA in the 70S ribosome, ArfA and RF2 interact such that the GGQ peptide hydrolysis motif of RF2 rises into the peptidyl-transferase center and releases the ribosome (PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:28077875).  Recruited by ArfA to rescue stalled ribosomes in the absence of a normal stop codon (PubMed:22857598, PubMed:22922063, PubMed:25355516).
What are the official names of this protein?
Peptide chain release factor RF2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Recruited to the 70S ribosome by ArfA even in the absence of mRNA (PubMed:22922063, PubMed:25355516, PubMed:27934701).
Protein: Y8295_DICDI
Sequence: MRLLLALFFVLALVSPSFTQVWSNCGTAADKFQITNVVLDPPTPVKGQDITISASGILDETVTGGNVAVKVKYGFITLINENVSICSSQDPLACPIAAGDYQKNMTEMIPSDAPSGKYTGNVVITDQNNAEIACIDVDINL
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0278295.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: DLGP4_HUMAN
Sequence: MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
What is the function of this protein?
May play a role in the molecular organization of synapses and neuronal cell signaling.  Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton.  May induce enrichment of PSD-95/SAP90 at the plasma membrane.
What are the official names of this protein?
Disks large-associated protein 4, DAP-4, PSD-95/SAP90-binding protein 4, SAP90/PSD-95-associated protein 4, SAPAP-4.
What is the protein family that this protein belongs to?
Belongs to the SAPAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: Y3631_BACCZ
Sequence: MAMRFLNIGYGNIVSAHRIIAIVSPESAPIKRTVQEAREHNALLDATYGRKTRAVIVMDDGHVVLSPIQPETIAHRLNNKEDLSEEG
What are the official names of this protein?
Putative regulatory protein BCE33L3631.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: NRDR_XANC5
Sequence: MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVAEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RTCA_SULTO
Sequence: MIEIDGSFGEGGGQILRTSLTLSALTKKPFRIYKIRANRPKPGLQRQHLTAVEAVKKLTNAKVKGDFVGSTELVFEPEDIVEKGDFEFDVGTAGSVTLILQTILPLLINRNIKVTIKGGTDVPKSPSIDYIRLTFLSLLEKIGIRVNLILIRRGHYPEGGGEIKITEVKGNPSSFSLMERGELLMIKGISHVSSLPSHIAERQAKSAKEFLLSKIKIPVEIEIDVRENERSKGSGIALTAIFEKTFLGSDSLGEKGKRAEIVGEEAAKSIYEEIISNATVDRHMSDMLMLYASLYYGEYIGSELTSHARTNSEIIKKFLNVNIQISGEKPFIFRAKKEL
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_RICCK
Sequence: MRSAKLKFEKRRSRIRHKISQTSNRVRLSIFKSCRHIYAQIIDDSKSITIASASTLDAKIKKLKKSHCNIENAIKVGKAIATKADSAGIKEVVFDRGGYKYHGVVKALADAAREKIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SCP31_ARATH
Sequence: MDNYQTKNISNLLTSLCFTTLLILAPVVICTRQHRFDSPKRSLLANEQDLVTGLPGQPDVSFRHYAGYVPVDESNGRAMFYWFFEAMDLPKEKPLVLWLNGGPGCSSVGYGATQEIGPFLVDTNGNGLNFNPYAWNKEANMLFLESPVGVGFSYSNTSSDYQKLGDDFTARDAYTFLCNWFEKFPEHKENTFYIAGESYAGKYVPELAEVVYDNNNNNKKNGSSFHINLKGILLGNPETSDAEDWRGWVDYAWSHAVISDETHRIITRTCNFSSDNTWSNDECNEAVAEVLKQYHEIDIYSIYTSVCIGDSARSSYFDSAQFKTNSRISSKRMPPRLMGGYDPCLDDYARVFYNRADVQKSLHASDGVNLKNWSICNMEIFNNWTGSNPSVLPIYEKLIAGGLRIWVYSGDTDGRVPVLATRYSLNALELPIKTAWRPWYHEKQVSGWLQEYEGLTFATFRGAGHAVPCFKPSSSLAFFSAFLSGVPPPPSR
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 31.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_LEGPA
Sequence: MNEVYVFTSESVSEGHPDKIADQISDAILDAILAQDPKARVACEVLVKTGMVLVGGEITTKAWVDVEEITRHVIKDIGYNSSQMGFDWESCAVLSAIGKQSPDIAQGVDNQQTKILGAGDQGLMFGYASRETDVFMPAPIAYAHRLMEKLAKARKSGQLPWLRPDAKCQLTLKYEQGMPVEVDTVVFSTQHSPDIEHKDLVEAIREEIIKSVLPAEWLNDKTRYFINPTGRFVIGGPLGDCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCELQISYAIGVAEPTSIFVDTFGTGRLKNSEIIDLIHTHFDLTPQGIIDQHDLLRPIYRQTATYGHYGRENFPWERLDKVAELSKAL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_MYCTU
Sequence: MTLKLHDLRPARGSKIARTRVGRGDGSKGKTAGRGTKGTRARKQVPVTFEGGQMPIHMRLPKLKGFRNRFRTEYEIVNVGDINRLFPQGGAVGVDDLVAKGAVRKNALVKVLGDGKLTAKVDVSAHKFSGSARAKITAAGGSATEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ESAI_PANSE
Sequence: MLELFDVSYEELQTTRSEELYKLRKKTFSDRLGWEVICSQGMESDEFDGPGTRYILGICEGQLVCSVRFTSLDRPNMITHTFQHCFSDVTLPAYGTESSRFFVDKARARALLGEHYPISQVLFLAMVNWAQNNAYGNIYTIVSRAMLKILTRSGWQIKVIKEAFLTEKERIYLLTLPAGQDDKQQLGGDVVSRTGCPPVAVTTWPLTLPV
What is the function of this protein?
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR.  OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein EsaI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: IL12A_PIG
Sequence: MCPLRNLLLVATLVLLNHLDHLSLGRSLPATTAGPGMFKCLNHSQNLLKAVSNTLQKAKQTLEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLAARETSLITNGNCLTSGKTSFMTTLCLSSIYEDLKMYHVEFQAMNAKLLMDPKRQIFLDQNMLTAITELMQALNFNSETVPQKPSLEELDFYKTKIKLCILLHAFRIRAVTIDRMMSYLNSS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_BACLD
Sequence: MAETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNLDIVLFTLAGSSLIIAGSCVINNFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTALGFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTIIGSVSGAVPPLIGWTAVQGSIGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLMPLPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMVVFTLFKIG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_PSEPF
Sequence: MSASTTATLRHDWTLAEVKALFVQPFNDLLFQAQTVHRAHFDANRVQVSTLLSIKTGACPEDCKYCPQSGHYNTGLEKEKLMEVQKVLEEAARAKAIGSTRFCMGAAWKHPSAKDMPYVLKMVEGVKAMGLETCMTLGRLDQDQTEALAKAGLDYYNHNLDTSPEFYGSIITTRTYAERLQTLAYVRDAGMKICSGGILGMGESLDDRANLLIQLANLPEHPESVPINMLVKVAGTPLENADDVDPFDFIRMLAVARILMPQSHVRLSAGREAMNEQMQALAFFAGANSIFYGDKLLTTANPQADKDMQLFARLGIQPEAREEHADEVHQAAIEQALVEQKSSEQFYNAAV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CDC6V_METTF
Sequence: MFEKRPRLFKNRDVLSPLFVPDTLQDRKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVTTKYVINELEKHTSDAVIEYIVADGTAYQVATSIARAPRRGLGFLNIVEKIRERASEGKMIIVMDEIDKTLSRDGDKLLYHLSREPNVCIVGLSNKLTVMDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQRNGDARYALDLLSFAADIAIRQLKGVVSESDVRMATDEVEVEFIRRSIEQLRDNQKILLYAVMTSHGGTPTEIYRKYNKMTEEQFGGNALTQRRLSQLLRELELYGLVEIEVVGRGRGRGVNWHVVPSSSIDPELMLEAIRRSL
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: CUX4_CONCL
Sequence: RPKCCCVCGVVGRKCCSTWDKCHPVHLPCPSS
What are the official names of this protein?
Conotoxin Cltx-4, CalXXIXA.
What are the subcellular locations of this protein?
Secreted.
Protein: RT14_ACACA
Sequence: MKYLLIKNKKLYKLFFKFELKRLQYKSVMLNTRLPNYIRQKAFMYINKLDKNTSYVAIKQRCFLSNNGRSVLNHFKLSRIKLRLLISNNYVNGVKKFNK
What are the official names of this protein?
Ribosomal protein S14, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DPH1_YEAST
Sequence: MSGSTESKKQPRRRFIGRKSGNSNNDKLTTVAENGNEIIHKQKSRIALGRSVNHVPEDILNDKELNEAIKLLPSNYNFEIHKTVWNIRKYNAKRIALQMPEGLLIYSLIISDILEQFCGVETLVMGDVSYGACCIDDFTARALDCDFIVHYAHSCLVPIDVTKIKVLYVFVTINIQEDHIIKTLQKNFPKGSRIATFGTIQFNPAVHSVRDKLLNDEEHMLYIIPPQIKPLSRGEVLGCTSERLDKEQYDAMVFIGDGRFHLESAMIHNPEIPAFKYDPYNRKFTREGYDQKQLVEVRAEAIEVARKGKVFGLILGALGRQGNLNTVKNLEKNLIAAGKTVVKIILSEVFPQKLAMFDQIDVFVQVACPRLSIDWGYAFNKPLLTPYEASVLLKKDVMFSEKYYPMDYYEAKGYGRGETPKHAIE
What is the function of this protein?
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:15485916, PubMed:24422557, PubMed:27694803, PubMed:31463593, PubMed:34154323).  In association with DPH2, transfers a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1 (PubMed:15485916, PubMed:31463593, PubMed:34154323, PubMed:24422557, PubMed:27694803).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_PARMW
Sequence: MARPVVAIIGRPNVGKSTLVNRLCRSREAIVHDEPGVTRDRTYQDGYWGDREFKVVDTGGLVFDDDSEFLPEIREQAALAMEEASVAVVIVDGQQGITAADESIAEFLRSRPCPTLLAVNKCESPEQGLAMAAEFWSLGLGEPHPISAIHGVGTGDLLDQVLTFLPPKDQEGDEEEPIQMAIIGRPNVGKSSLLNAICGEQRAIVSPIRGTTRDTIDTNIVRENRPWRLVDTAGIRRRRSVNYGPEYFGINRSFKAIDRSDVCVLVIDALDGVTEQDQRLAGRIEEDGRACVVVVNKWDAVEKDSHTMTAMEKELRAKLYFLDWAPMLFTSALTGQRVDSIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTTRGGRQGRLYYGTQVASRPPSFTLFVNDPKLFGDTYRRYVERQIREGLGFDGTPVKLYWRGKQQRDAERDMVRQQNRQS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ORD_UNKP
Sequence: MGKNVKTLIWGFGAMGSGMASILLEKGGYELVSVIDTHPQKAGKDVGELLGRAPLGVKVTMDHLKAFGSHPDVALIATSSFVEEVSPQIEFALENDANVITIAEEMSYPWIDSKEIAERLDALALNRGKTVLGTGINPGFVLDTLVVSLSGVCKEVRHIHAKRVNDLAPFGPTVMRTQGVGTTPEKFEEGIRSGNIVGHIGFRQSIMLIAKALGWTIEDIVEERQPIITNVRRKTNYVDVTPGNVAGCRHTARAYSCGREVIFLEHPQQVCPEAEGVRTGDYVVIDGDPPVNLRIEPEIPGGTGTMAMAVNMIPLVVNAPPGLLTMIDLPVPRSISNGF
What is the function of this protein?
Involved in the ornithine fermentation pathway.  Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate ((2R,4S)-DAP) to yield 2-amino-4-ketopentanoate (AKP).  Although Ord is more efficient with (2R,4S)-DAP, the diastereoisomer (2R,4R)-DAP can also be metabolized.  Ord is specific for NAD as hydrogen acceptor.
What are the official names of this protein?
2,4-diaminopentanoate dehydrogenase, DAPDH.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
Protein: INCC2_ECOLX
Sequence: MGVIHEETAYRKPVPGGDPGAGSGAADHRDSAGRLSRWEATGDVRNVAGTDQGRSVASGASRVGRVRGQELARGVRAGNGGSAGTSGVHRPEVGSGRQEKTGNQTMKTLVTANQKGGVGKTSTLVHLAFDFFERGLRVAVIDLDPQGNASYTLKDFATGLHASKLFGAVPAGGWTETAPAAGDGQAARLALIESNPVLANAERLSLDDARELFGANIKALANQGFDVCLIDTAPTLGVGLAAALFAADYVLSPIELEAYSIQGIKKMVTTIANVRQKNAKLQFLGMVPSKVDARNPRHARHQAELLAAYPKMMIPATVGLRSSIADALASGVPVWKIKKTAARKASKEVRALADYVFTKMEISQ
What is the function of this protein?
This is one of the proteins encoded by the trfB operon; it is involved in plasmid maintenance and replication.
What are the official names of this protein?
Protein IncC.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: Y1913_HALHL
Sequence: MRIWVDADACPGAIKEILFRAAQRTGVELTLVANHPIRVPPSPVIRSVQVAAGFDVADHEIVRRVAAGDLVITGDIPLAAEVIEAGAQALNPRGERYTPETIRERLNMRDFMDTLRASGVDTGGSAALSQRDRQAFANELDRILARRPSQG
What are the official names of this protein?
UPF0178 protein Hhal_1913.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: ILVD_CAMJJ
Sequence: MRSDAIKKGHLKAPNRSLLRACGLKDEDFDKPFIGVANSYIDIIPGHYFLNDYAKIIKDEIRKNGCVPFEFNTIGVDDGIAMGHEGMLYSLPSREIIANSIETVMNAHQLDALICIPNCDKITPGMLMGALRVNVPTIFVSGGPMASGVTKKGEKISLSSVFEAVGAYEAKKISEEEFKDIECSACPSGGSCSGMFTANSMNTLCEAMGIALEGNGTILALSKEREELLRKAARRICEIALDERFKIRNIITQKAVRNAMVVDMAMGGSSNTVLHMLAISREAGVALDIKDLNFISSKVAHIAKIAPSLNSVYMDDIHKAGGVSAVMAEISSRQGHILELDALTITGESLEERLKNAKIKDENIIRKVDNAYSKVGGLAILFGNLAEQGCVIKTAGIIGERKFKGEAVCFNSQDEAIKGIIKGKVKKGNVCVIRYEGPKGGPGMQEMLSPTSLLMGMGLGADVALITDGRFSGATRGLSVGHISPEAAEGGLIGLLKDGDEIEIDVDAYTIHANLSEEEITQRKKEFVLPQKEVPSRWLRMYQKLVSNASKGAVLDME
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: BAG6B_XENLA
Sequence: MAANEKMDVTVKTLDSQTRTFTVEAEILVKEFKAHISSAVGITPEKQRLIYQGRVLQEDKKLNEYNVDGKVIHLVERAPPQTQTSTSGPSTSSSTSPSSSNAAPVPGAPERNGNSYVMVGTFNLPHVMSGLGEASRGPSVSTISGSEPRVRLVLAQNILQDIQRNLDRLEGQPGNEQAAEPMDTAESEGEASSRETLPQTTQNADGQSNSTPTSHPSPSEYVEVLQSLSRVEERLAPFMQRYREILSSATSDTYENQEREQSQRIINLVGESLRLLGNALVAVSDLRCNLSSASPRHLHVVRPMSHYSGPMLLQQAAIPIQINVGTTVSTTGNGTHAGHVPSDGNATPSTNTSEHQRSNSENQPPPSGERPASDAPPNSVPHPHPRVIRITHQTVEPVMMMHMNIQDSASGGPTNIPPPTAGHGGSAHIHMPGLPPEFMQAISNQITQQAMAAASGQQIPGFQAPPRFVFTRPAAPSFNFQPGAAATTPPAPGGATTTAPGATVGPAGNASLAQMISGLVGQLLMHPVVVAQGGSSTSSTTSTSTSTSTSSSTSSSSSTVPTSTTTTTSTSFPNVSSVPSAQLPPGTDQHLSQLLGSLLGTASSGMSNLTMGSPSITVTVPGMPAFLQGVTDILQATQTVPVSTSPPQSASQAPPPPSSPAPPAHSAPPPAAAPESLPPEFFTSVVQGVLSSMLGSLSAADQSGTESIADFIQRLSGSHNIFQPDAEGPGGFFGDLLTLICHNFSLVDMVMLLHGHSQPLQNLQPQLRSFFLQEYLHQADPTPNNIQMASRNLTNGLEEYIRESFASVTVRDDVDITRTNLEFLQDQFNRITTHILHCADSTFGQRLLEMCNQSLFEWLALNLYCLRGDQNALTSVINERIRRLSLDVSPVLVSWVTSVLSLRLQVLLGQMPVTEGEIQRHVRRVGDASQVPEPSSQEQPMETMPVDFQQNGAASPVPATTVEEVLFLPPQSSVPTICPDSEHPTQGDSVSEQWTASVPPEWVPVIRQDLQNQRKIKQQPPLSDAYLSGMPAKRRKTMQGEGPHLSLSEAVSRAMKVTGAKPESSTECVKRELDNSEAQGEYKEQLCQDIQEILQDDESYTAQRFPNTHRAFRGDP
What is the function of this protein?
When nuclear, may also act as a component of some chromatin regulator complex.
What are the official names of this protein?
Large proline-rich protein bag6-B, BCL2-associated athanogene 6, HLA-B-associated transcript 3-B.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome.
Protein: RL361_YERPE
Sequence: MKVRASVKKLCRNCKIVKRNGVVRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HXA5_HETFR
Sequence: MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQYRDSATMHSSRYGYGYNGMDLSISRPASNHFNASERSRSYSAAAATTAAAAGPEAGADTRYNQPATSSPSPDPLPCSAVVSPSAGDNHHGIKNSIASPTTSSNSSSSSSHISRDGVGTSPGTEDDTPASSDPPSSQNGQSTAQQQPQIYPWMRKLHISHDSMGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGGYRP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A5.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGT_STAAM
Sequence: MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
What are the official names of this protein?
Monofunctional glycosyltransferase, MGT, Peptidoglycan TGase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS5_RHOE4
Sequence: MPGRQRRDGGSGPAGQNGPNSGDNSNARGDNRGGGRDRRDGGRGGNAAEKSQFIERVVTINRVSKVVKGGRRFSFTALVIVGDGNGLVGVGYGKAKEVPAAIQKGVEEARKSFFRVPMIANTITHPVQGEAAAGIVMLRPASPGTGVIAGGAVRAVLECAGIADILSKSLGSDNAINVVHATVAALKGLQRPEEVAARRGLTLEEVAPAGMLRARAQAAGSVK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RLMD_CUPMC
Sequence: MSSQPNPTSHPEAASAASAASNDPVVKIDSLDMEARGVGRLENEDGTPGKVIFVEGALPGETVAYRSYRRKPSYEQAHLVEVKQASVMRVKPGCQHFGVCGGCSMQHLDSRAQLAIKQRVLEDNLWHLSKVKPDVVFRPIAGPDWGYRYRARLTVRHVVKKGGVLVGFHERKSSYVADMTHCEILPPHVSAMLVPLRELVGGLSIHDRMPQIELAVGAEVTALVLRVLEPLNDADKDLLRAFADQHQVQFWLQPKGPDTVYPFYPAEQELAYTLPEFGIRMPFKPTDFTQVNHQINRVLIGRALRLLDAKPTDRLLDLFCGIGNFTLPLATQGASVMGIEGSEVLTTRALANAEYNGLAAKTSFACRNLFEVTAEDIAALGRFDRWLVDPPREGALAVCKALAELSQAGSDVLPKRIVYVSCSPATLARDAGLLVHEAGYRLAGAGVVNMFPHTSHVESIAVFERD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.