PharMolix/UniProtQA huggingface dataset:
Protein: SPNE_DROVI
Sequence: MDSDLMDFFDFSKQFKRGTALKGCITGDPNALTTESRDSKPIKREKIGTDYVNEIVEKEKQLMNKLVDGQSVAKRNRTLDELDSDDEEENMQEQPSVRSDEAYYEKYRFDLNRNKNLPIYAQREQIMKAIRENPVVILKGETGCGKTTQVPQYILDEACKRREFCNIVVTQPRRIAAISIANRVCQERQWQPGTVCSYQVGLHRQSNVEDTRLLYCTTGVLLNNLIRLKTLTHYTHIVLDEVHERDQDMDFLLIVVRRLLALNSRHVKVILMSATIDTREFSKYFATSSAFPPVVTASHGRKYPLVKYYRDQLKNIHWKDEPQERAPGIGPEGYADAIKILLVIDNMERKAVGQSLQSYEEAKRTGSVLIFLPGINEIDTMADHITSVMEENPTMIITIVRCHSLMSPDSQEEVFQPPLPGHRKIILTTNIAESSITVPDVSYVIDFCLTKVLHTDTATNYSCLRLEWASKVNCRQRAGRVGRLRSGRVYRMVSKAFYLEEMKEFGIPEMLRSPLQNSVLKAKELEMGRPSEILALAMSPPNLSDIQNTVLLLKEVGALYTTVDGVYEELDGDLTYWGTIMSRFPLDVRLSRLIILGYVFNCLEEVIVIAAGMTVRSLYLTGKRRQVNDAFWMHYIFADGSGSDMVAIWRVYRIYLNMCQDRMLKESAEQWARRFNVNLRSLKEMHLMVQELRQRCASVNLQPLPYGTCQMWDDREKSIILKVIIAGAFYPNYFMRSNKSNADYDRSLFQSICGNDPCRTVFFTHYEPRYMGELYTRRIKELFLEVKIPPENMDVTFLHGSEKVFVTFKSDDEDMDTAKVVQVPGRVMTEVYKAVRMRLENQNRPLRVMDQNSALRYVQDRKIGVVTEGTWFPPSNQWNVELLTLPSVFAKNITGLVTYIVSCGKFYFQPRALAESIASMSEIFNGPQQLSCHVRNASAVTKGLQLLAKRGHLFQRAVVLRIETQTNGHPRFRVRFIDYGDMAVLPMDQLRLMPHELKRDFDQLPPRMFECRLALVQPSMVTSSYNRWPKAANDMLISVAQCGRLELEVYSLVNNVAAVLIHMRDGVLNDRLVERQLARRADEDYMSRKDHDLRIRKQEAKRNISVAEQERINEEYLRFAQLPKDMDLEPPPLDKCNLSIRLRGPFSPLESSMNSMLRIGMYKSVTIDKDSVNAVLLDTDPQDRHDQMVVAASVTETDNTERLTARGTTLMPNIHGFGALMAMLFCPTMQIKCNKDRTKYVCLLAGLGFDPETLEPYFAEHDMVINLDVTILRDDIRIINQMRYNIDSMFYNFDANEMPSVGTEDRVVIFNQLRSLLTRLLGKDRSFIERHVSNSEYLWEDMSDLEPPSEPYGKRAIFPMHSSYDLENDNLSNLLELQANCKQLYDWRNFEGNLQTQVCRLCNESLESVAELRLHLLTQLHRDREKQVGYKQQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: AGL15_ARATH
Sequence: MGRGKIEIKRIENANSRQVTFSKRRSGLLKKARELSVLCDAEVAVIVFSKSGKLFEYSSTGMKQTLSRYGNHQSSSASKAEEDCAEVDILKDQLSKLQEKHLQLQGKGLNPLTFKELQSLEQQLYHALITVRERKERLLTNQLEESRLKEQRAELENETLRRQVQELRSFLPSFTHYVPSYIKCFAIDPKNALINHDSKCSLQNTDSDTTLQLGLPGEAHDRRTNEGERESPSSDSVTTNTSSETAERGDQSSLANSPPEAKRQRFSV
What is the function of this protein?
Transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway.  Acts as both an activator and a repressor of transcription.  Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'.  Participates probably in the regulation of programs active during the early stages of embryo development.  Prevents premature perianth senescence and abscission, fruits development and seed desiccation.  Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4.  Can enhance somatic embryo development in vitro.
What are the official names of this protein?
Agamous-like MADS-box protein AGL15.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Associated with the chromosomes during mitosis. Accumulates in the egg cytoplasm before fertilization but moves into the nucleus of the fertilized egg.
Protein: PINP1_PINPI
Sequence: MGVFSSPMSTLRWVTLFAALLSLLEWGTAHEDIVMDGDQVVQQQGRSCDPQRLSACRDYLQRRREQPSERCCEELQRMSPHCRCRAIERALDQSQSYDSSTDSDSQDGAPLNQRRRRRGEGRGREEEEAVERAEELPNRCNLRESPRRCDIRRHSRYSIIGGSD
What are the official names of this protein?
2S albumin seed storage protein PINP1.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: EX7S_YERPE
Sequence: MPKKAASPEIKAASFETSLSELEQIVTRLESGELPLEDALNEFERGVQLARQGQQTLLQAEQRVQILLSDDVDAPLKPFTPDTE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HB24_MOUSE
Sequence: MVWLPRVPCVAAVILLLTVLSPPVALVRDSRPWFLEYCKSECHFYNGTQRVRFLKRYFYNLEENLRFDSDVGEFRAVTELGRPDAENWNSQPEILEQKRAAVDTYCRHNYEIFDNFLVRRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS
What are the official names of this protein?
H-2 class II histocompatibility antigen, E-Q beta chain, E-W17.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL3_MYCPN
Sequence: MEIRGIFGVKVGMSQVFTTNNERLPITVIYCEPNQVAGVKTEAKDKYSATLLSFDTVENKKLNKPQQGFFEKNNLKPTKHLQEIRNMTGFEMGQQITPQNLFQVGEYVDVSAISKGRGFTGAIKRWNFKIGPLGHGAGYPHRFQGSVQAGRGGASAQRVFKGKKMSGHYGHEKVTVQNLRIVGFDEANMLVLVSGAIAGPEGGVVLIRTAKKKPGVVKPIELAVQTEKAPEAKPAKLSKKKQAKELAKAQAANQQTVEAKVDTPVVEPKPTEVKKAAPVVEKKGEDK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RLMKL_PSESM
Sequence: MSDRYELFLTCPKGLEGLLAEEATALGLQETREHTSAIRGSADMETAYRLCLWSRLANRVLLVLKRFPMKDAEDLYHGVLDVEWHDHLEPEGTIAVEFSGHGSGIDNTHFGALKVKDAIVDKLRTPEGERPSVDKINPDLRVHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAILIRAGWPRIAAEGGALADPMCGVGTFLVEAGMIAADIAPNIKRERWGFSAWLGHVPTLWRKLHDEALARAEAGLAKTPSWIRGYEADPRLIQPGRNNIERAGLSDWIKVYQGEVATFEPRPDQNQKGLVICNPPYGERLGDEASLLYLYQNLGERLRQACLNWEAAVFTGAPDLGKRMGIRSHKQYSFWNGALPCKLLLIKVTPDQFVTGERRTPEQRQVERENPVEVEVVERKLNKNGNPIKPEPVVVEQARLSEGGQMFANRLQKNLKLLGKWVRREGIDCYRVYDADMPEYSLAIDLYHDWVHVQEYAAPKSIDPEKASARLFDALAAIPQALNIDKSRVVIKRRERQSGTKQYERQSAQGQFLEVSEGGVKLLVNLTDYLDTGLFLDHRPMRMRIQREAAGKRFLNLYAYTATASVHAAKGGARSTTSVDLSRTYLDWARRNLSLNGFSDKNRLEQGDVMAWLQANRDEYDLIFIDPPTFSNSKRMEGIFDVQRDQVELIDLAMARLAPGGVLYFSNNFRKFVLDENLGQRYAVEDITAQTIDPDFARNGKIHRAWKITARA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_AGARV
Sequence: MPIKTQNDLPVKEILERENIFVMDENRASHQNIRQLEIAIVNLMPLKEDTELQILRSLSNTPIQVNVTFVTTSTHEATHTSLSHLNKFYETFDDIKDRYFDGMIITGAPVELMEYEEVDYWDEICSIMEWSKTHAFSTLHLCWGAQAGLYYHYGIPKRVLPKKKFGVYAHRVKNRKIPLVRGFDDVFYAPHSRHTEVLKEDILKHPELTILAESDDAGVFLLMDQDGKKIFVMGHPEYDRYTLHNEYERDKKKGLDIDMPVNYYPDNDDTQKPLLQWRSHGNILYSNWLNYYVYQEVPYEFINNREIIGK
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI1_METMA
Sequence: MRFKELAELFEELEKTTSHREIVRKISEFFKNLRGDEVKDSAYLFLGSTGPAFENTTLGIKDMLAIRAIAGAYGVTREDVRKRYARTGDLGDVAFELSKKRESSLTIEDVFQRLLQIRETSGKGSQEEKTALFSDILQKATPEEGKYIVRLVLGRLRLGFGDQFLLEAFAIAFTGDKKHAAKIKESYSVCTDIGELAKILAENGARATGFISIKPGRPVKSMLSQRVESFEELEKRVKGKKAAEEKYDGERVQVHKTGEGIKAFSRRLEDITSQYPEIIEDVRKTVPANEIVLDGEIVAYAELERNGNRIEEFYPFQNLMQRRRKYEIENYRKKCPVAVFFFDILYLNGEPLLKRPYPERRALLEMNVVESGIIRLSKRIVTESVEEIEDFFNETIEKGLEGIVVKSMSSNSYYEAGKRSWFWFKWKQEYSEGMRETFDLVVVGSYYGRGRRKGSFGALLCAVLNKEGQRFETLTKVGTGFTEADAEEINRLLSDHIVSEIPKGVSIKKGMLPDIFIEPAVVIEVLGSEITNSPGHTAGEGEEETGLALRFPRFLRIRHDKTPYDAMTVKEVRDLKDGT
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase 1, Polydeoxyribonucleotide synthase [ATP] 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: MUTL_STRU0
Sequence: MSKIIELPEILANQIAAGEVIERPASVVKELVENAIDANSRQITIEIEESGLKSIKITDNGEGMSEENLPLSILRHATSKIKNQSDLFRIRTLGFRGEALPSIASISELRIETSTADSPYGSLLVAKGGQIERQEVISTPVGTKITVENLFYNTPARLKYMKSLQSELAHIVDVVNRLSLGHPEVSFTLICDGREMTKTSGTGDLKQAIAGIYGLNTAKKMIEISNADLDFEVSGYVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISTAIAESLKSQDLIPDALENLAKSTVRSSTKYEQTKLPLQSSKLYFDPQKNDFYIKEPQKTTELTVSEESPNFTLYTNIDNTVKEDRNLDQTSASASVKHASRSQDENQLSEHPNLDFTNKQKMEQLISKLENEKTSTFPELDFFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGKVDTSLQQLLVPYLFEFSGADFIQLQEKMSFLNEVGIFLEPYGMNTFILREHPIWMKESEIESGVYEMCDMLLLTNQVSIKTYRAELAIMMSCKRSIKANHALDDYSARHLLEQLSQCQNPYNCPHGRPVLVHFTKADMEKMFRRIQENHTSLRDLGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: NIAR_THEMA
Sequence: MHMKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGGKSGVSRLVAVKHAPEEIKEELLCVVRNGGRIVDVIVEHPVYGEIRGIIDVSSEEEVLKFVNLMEMAKTEPLLTLSGGVHLHTIEAPDEETMERIMRELKKKGFLIEEG
What is the function of this protein?
Probably functions to regulate transcription of NAD metabolic genes.  Binds to DNA upstream of the probable nadBII/nadA/nadC and niaRP operons in a nicotinic acid dependent fashion.  Nicotinic acid may be a corepressor.
What are the official names of this protein?
Probable transcription repressor NiaR.
Protein: ASSY_EXIS2
Sequence: MTKQKLILAYSGGLDTSVAIKWLSKDYDVVALCMDVGEGKDLSVIKEKALLVGAIESIVLDVKDEFANDFVLPALQYGAHYEGAYPLISALSRPLIAEKLVEVAHAQGATAVAHGCTGKGNDQVRFEVSVAALDPSLEVIAPVREWKWSREEEIAYAKENNVPIPINLNSPYSIDMNLWGRSNECGVLENPWTEPPQDAYALTVAPEDAPDQAEEVIIGFEAGVPVSINGTAYPLAKLITELNIIAGAHGVGRIDHVENRLVGIKSREVYECPGATVLLKAHAALETITLTKDVAHFKPILSKQYAETIYNGLFHAPLTKGLKAFLTATQQDVTGEVRVKLYKGNATVTGRQSAVSLYDEKLATYTKEDAFDHEAAKGFIKLHGLAISTHASVHRQEGVKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_LISMF
Sequence: MKITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEAEIEEIKQADMVRKGLNKAINFLSHRVRSEKEIRDYLRKQEMEAFAIDEILKKLADMDYINDLEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIITQVIEEYSDEAQLENATKQAIKIMKRNNKSAKKMLQQKIITDLIQKGYTSELAKVAATEATSELDVADEAEILQKQIEKTMRKNKRYKPSIAKQKTITSLMQKGFSYDTIQSYLTENEISFEEEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_XANAC
Sequence: MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPAPAKAASGD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RNPH_MOOTA
Sequence: MLRANGRGLRELRPVTIERHYLKYAEGSALITVGDTRVICSATVEEKVPPFLKNTGKGWITAEYSLLPRSTKERTIREVTRGRLTGRTQEIQRLIGRSLRSVVDMSLLGERTIWLDCDVLQADGGTRTAAITGSFVALAEALAGLVAAGGVPAMPLKDFLAAVSVGLVDDELILDLDFQEDSHAGVDMNVVMTGSGQLVEVQGTAEGRPFTREQLTAMLDLAGEGIESLIAIQKQVLGDIASRVGTGNDK
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MATRX_HENDH
Sequence: MDFSVSDNLDDPIEGVSDFSPTSWENGGYLDKVEPEIDKHGSMIPKYKIYTPGANERKFNNYMYMICYGFVEDVERSPESGKRKKIRTIAAYPLGVGKSTSHPQDLLEELCSLKVTVRRTAGATEKIVFGSSGPLHHLLPWKKILTGGSIFNAVKVCRNVDQIQLENQQSLRIFFLSITKLNDSGIYMIPRTMLEFRRNNAIAFNLLVYLKIDADLAKAGIQGSFDKDGTKVASFMLHLGNFVRRAGKYYSVEYCKRKIDRMKLQFSLGSIGGLSLHIKINGVISKRLFAQMGFQKNLCFSLMDINPWLNRLTWNNSCEISRVAAVLQPSVPREFMIYDDVFIDNTGKILKG
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Forms a shell at the inner face of the plasma membrane (By similarity).
What are the official names of this protein?
Matrix protein, Protein M.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Note=During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: MMPLA_MYCBO
Sequence: MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKTFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSLNSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDASQPSMAGFNVPPQVLKSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQRCAPEEGQMSARMSARTKTVFQAVADGSKR
What are the official names of this protein?
Probable transport protein MmpL10.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNP29_ARATH
Sequence: MAPKNSSWNPFDDEKEAAKSFSLNPFDDDDDDKEVEKRFTSSLKPSGGKENQTVQELESYAVYNSEETTKTVQGCLKVAEEIRCDASKTLVMLNEQGDQITRTHQKTVDLDHHLSRGEKILGRLGGVFSRTWKPKKSRSITGPVITKGDSPKRKVIDLKTREKLGLNPSLKPKSKTLPEAVDAYQKTQIAKQDEALTDLSALLGELKNMAVDMGTAIERQTNELDHLQDNADELNYRVKQSNQRARYLLRK
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.
What are the official names of this protein?
SNAP25 homologous protein SNAP29, AtSNAP29, Synaptosomal-associated protein SNAP25-like 2.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: THIO_PIG
Sequence: MVKQIESKYAFQEALNSAGEKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVVFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELI
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).  Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.  Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.  Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA). Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. Secreted by a leaderless secretory pathway.
Protein: CYSG_ECO57
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: EVA1C_PANTR
Sequence: MLLPGPARQPPTPQPVQHPGLRRQVEPPGQLLRLFYCTVLVCSKEISALTDFSGYLTKLLQNHTTYACDGDYLNLQCPRHSTISVQSAFYGQDYQMCSSQKPASQREDSLTCVAATTFQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDQELKLHCHESKFLNIYSATYGRRTQERDICSSEAERLPPFDCLSYSALQVLSRRCYGKQRCKIIVNNHHFGSPCLPGVKKYLTVTYACVPKNILTAIDPAIANLKPSLKQKDGEYGINFDPSGSKVPRKDGILVSNSLAAFAYIRAHPERAALLFVSSVCIGLALTLCALVIRESCAKDFRDLQLGREQLVPGSDKVEEDSEDEEEEEDSSESDFPGELSGFCRTSYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY
What is the function of this protein?
Binds heparin.
What are the official names of this protein?
Protein eva-1 homolog C, Protein FAM176C.
What is the protein family that this protein belongs to?
Belongs to the EVA1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: KTHY_STRPN
Sequence: MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGVLIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSSVAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDLEGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NADK_TROWT
Sequence: MRVYIAHNGCLEAEPIYGTICELVAQRKMSVITDPHARNNESARNTDSGVVSLNQAGRNKYLDQETTSRSINVPFCAGISIGGDGTFLRMARDLKNTGTPLFGVNMGRMGFLVDIEPEDIVNLVENIVKGEYTEEKRLPITASVQRGGKKIHDEWAVNEITIERKVEGKVVDIEVFVDGCRVMDISCNGIIIATATGSTAYSFSSGGPIVWPEMKVTLVVPVSPHELFAKPIVLPDNRSILLKVTSRDNKVVLCSDGQVRLCLQSGDEIACHVGKVPVVFGRVKKGCFAEHLVKKFNLQTA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BACAH
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAFKVMRDIAAEGGDILFVGTKKQAQEAIKEEATRAGMYFVNQRWLGGTLTNFQTIQKRIKRLKDIERMQEDGTFEVLPKKEVVQLKKELERLEKFLGGIKDMKGLPSALFVVDPRKERIAVAEARKLHIPIIGIVDTNCDPDEIDHVIPANDDAIRAVKLLTSKMADAILEAKQGEETVTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LPXN_HUMAN
Sequence: MEELDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLFPL
What is the function of this protein?
Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF).  Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events.  Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN).  May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts.  Negatively regulates B-cell antigen receptor (BCR) signaling.
What are the official names of this protein?
Leupaxin.
What is the protein family that this protein belongs to?
Belongs to the paxillin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Nucleus. Cytoplasm, perinuclear region. Cell projection, podosome. Cell membrane. Note=Shuttles between the cytoplasm and nucleus. Recruited to the cell membrane following B-cell antigen receptor (BCR) cross-linking in B-cells. Enhanced focal adhesion kinase activity (PTK2/FAK) attenuates its nuclear accumulation and limits its ability to enhance serum response factor (SRF)-dependent gene transcription. Targeting to focal adhesions is essential for its tyrosine phosphorylation in response to bombesin.