PharMolix/UniProtQA huggingface dataset:
Protein: RBN_SALPB
Sequence: MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQHQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIATTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALNARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEAALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYDDKGCQRLLAECRAIFPATELAYDFSVFPV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: NUOB_BURVG
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTNTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GSA_MYCSK
Sequence: MGAHHTATEQSARLFADACAVIPGGVNSPVRAFNAVGGTPRFITSANGYWLTDADDNRYVDLVCSWGPMILGHAHPAVVEAVQRVAADGLSFGAPTPSETELASEIISRVAPVERLRMVNSGTEATMSAIRLARGFTGRPKIVKFSGCYHGHSDALLADAGSGVATLGLPSSPGVTGAATADTIVLPYNDVDAVEEIFEQVGDQIAAVITEASPGNMGAVPPEPGFNAALRRITEEHGALLILDEVMTGFRVSRSGWYGLDPVDGDLFTFGKVMSGGLPAAAFGGRAEVMERLAPLGPVYQAGTLSGNPVAMAAGLATLRTADDAVYAALDKNADRLAGLLTDALTDAGVTHRVQRGGNMLSVFFTAEPVGDFATARASETWRFPPFFHALLDAGVYPPPSAFEAWFVSAALDDEAFDRIAAALPGAARAAAEASRPA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_YERPS
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: LDB1_XENLA
Sequence: MLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRLQNWTEECDNLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGGATELYYVLKHPKESFHNNFVSLDCDQCTMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIKTWHFSIRQHRELIPRSILAMHAQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTYSLSPRDCLKTCLFQKWQRMVAPPAEPARQAPSKRRKRKMSGGSTMSSGGGNTNNSNSKKKSPASTFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPPSSQESKSENPTSQASQ
What is the function of this protein?
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors.  Acts as a coactivator together with otx2 to stimulate lhx1/lim1-mediated activation of the gsc promoter in the Spemann organizer.  Acts synergistically with lhx1/lim1 and ssbp in axis formation.
What are the official names of this protein?
LIM domain-binding protein 1, LDB-1, xLdb1.
What is the protein family that this protein belongs to?
Belongs to the LDB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3657_MYCBO
Sequence: MTQSSSVERLVGEIDEFGYTVVEDVLDADSVAAYLADTRRLERELPTVIANSTTVVKGLARPGHVPVDRVDHDWVRIDNLLLHGTRYEALPVHPKLLPVIEGVLGRDCLLSWCMTSNQLPGAVAQRLHCDDEMYPLPRPHQPLLCNALIALCDFTADNGATQVVPGSHRWPERPSPPYPEGKPVEINAGDALIWNGSLWHTAAANRTDAPRPALTINFCVGFVRQQVNQQLSIPRELVRCFEPRLQELIGYGLYAGKMGRIDWRPPADYLDADRHPFLDAVADRLQTSVRL
What are the official names of this protein?
Uncharacterized protein Mb3657.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: YL66C_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YLR466C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS10_GLUOX
Sequence: MDNQNIRIRLKAYDHRVLDNSTKEIVNTAKRTGARVRGPIPLPTHIERFTVNRSPHVDKKSREQFEIRTHRRLLDIVEPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SDRC_STAAR
Sequence: MNNKKTATNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLSGHEAKAAEHTNGELNQSKNEATAPSENKTTEKVDSRQQNNVEQSTTSNQPKVNESDNTSVKETTEEPQNTTSTQPTKKNNDATANKDNLAAQNISTQANDVSATPKTTTIKPRTLNRMAVNTVAAPQQGTNVNDKVHFSNIDIAIDKGHVNSTTGKTEFWATSSDVLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSTTNTTTYTFTNYVDQYTNVSGSFEQVAFAKRENATTDKTAYKMEVTLGNDAYSEEIIVDYGNKKAQPLISSTNYINNEDLSRNMTVYVNQPKNTYTKETFVSTLTGYKFNPDAKNFKIYEVTDQNQFVDSFTPDTSKLIDVTDKFKITYSNDNKTATVDLMNGQTNSNKQYIIQQVAYPDNTSTDNGKIDYTLDTDKTKYSWSNSYSSVNGSSTANGDQKKYNLGDYVWEDTNKDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLGNGTYSVEFSTLAGYTPTTVNAGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLKQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYFEEETSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKPMSATKDHHNKAKALPETGSENNGSNNATLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Mediates interactions with components of the extracellular matrix such as host NRXN1 to promote bacterial adhesion.
What are the official names of this protein?
Serine-aspartate repeat-containing protein C.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: ARAA_LATSS
Sequence: MLNTENYEFWFVTGSQSLYGEETLRSVEKDAKEIVEKLNASHQLPYPIVFKLVATTADNITKVMKEANYNDHVAGVITWMHTFSPAKNWIRGTKLLQKPLLHLATQFLNKIPYDTIDFDYMNLNQSAHGDREYAFINARLRKNNKIISGYWGDEDVQKAMAKWMDVAVAYNESFKIKVVTFADKMRNVAVTDGDKVEAQIKFGWTVDYWGVGDLVAEVNAVSEADIDAKYADLQKEYDFVEGQNTPEKFEHNVKYQIREYFGLKKFMDDRGYTAFTTNFEDLVGLEQLPGLAAQLLMAEGYGFAGEGDWKTAALDRLLKIMAHNEKTVFMEDYTLDLRQGHEAILGSHMLEVDPSIASDKPRVEVHPLDIGDKDDPARLVFTGMQGDAVDVTMADYGDEFKLMSYDVRGNKPEADTPHLPVAKQLWTPKQGLREGAVGWLTVGGGHHTVLSFAVDSEQLQDLSHLFDLTYVNIK
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: CSSB2_ECOLX
Sequence: MLKKIISAIALIAGTSGVVNAGNWQYKSLDVNVNIEQNFIPDIDSAVRIIPVNYDSDPKLDSQLYTVEMTIPAGVSAVKIAPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGNFMAGQKGSFPVKENTSYTFSAIYTGGEYPNSGYSSGTYAGNLTVSFYSN
What are the official names of this protein?
CS6 fimbrial subunit B.
What are the subcellular locations of this protein?
Fimbrium.
Protein: MSRP_ECO5E
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: YCGR_PECCP
Sequence: MMVEMKAVNENLKEQFVKRNKLAICATLRELKKNDTSLMVHHSHGQFISKILDVVPDNNLFVFDLGGIERENNRALYAGSLSFVAEPAGAKVEFNAEIAKTVTYDGLPAFSAQIPELLYLIQRRTYFRINTPLWPPLTCRGELPDESVFLFTIKDLSLGGLSLYTDRDTTGLLTEGDIIKSVEMDLADHGFFCVDLQFVGQAMVKVVDNKGEVQLTQRLSFKFPSLNAAQERDLQQVIFELERLQNEKKKRFQEL
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: QCR8_PONAB
Sequence: MGREFGNLTRMRHVISYSLSPFEQRAHPHVFTKGIPNVLRRFRESFFRVAPQFVVFYLIYTWGTEEFERSKRKNPAAYENDK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VIII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
What is the protein family that this protein belongs to?
Belongs to the UQCRQ/QCR8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: Y562_LISMF
Sequence: MRAVLTVIGKDNVGIVAGVSNKLAELNINIVDVSQTIMDGYFTMMMMCDISQITKEFDEVKAELAGKGEDLQVKIHIQREEIFNAMHKL
What are the official names of this protein?
UPF0237 protein LMOf2365_0562.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: MDTL_ESCF3
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMATMGIAVLMLSLFILKETRPAAPAASDKPRENRESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAISLFGITLICAGFSIGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVTPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDC37_CHICK
Sequence: MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDKGCRECKRKLAECQKKLKELEVAEPGGGSGGGRGERERLQAEAQQLRHEERNWESKMEELRKKEKNMPWNVHTLSKDGFSKSVFNVKAEEKEETEEQKEQKHKTFVERHEKQIKHFGMLRRWDDSQKYLSDNPHLVCEETANYLVIWCIDLEVEEKQALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADQQYMEGFNDELEAFKERVRGRAKARIERAMREYEEEERQKRLGPGGLDPVDVYESLPPELQKCFDAKDVQMLQDTISRMDPTEAKYHMQRCIDSGLWVPNAKAAAEGGGQGGAHGQPGGADSEALYEEIPKESGEEEGGEGKA
What is the function of this protein?
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
What are the official names of this protein?
Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUC3_FUSSX
Sequence: MDFTTFHNIIGGKPRGSDNSHSGVDPLTRTTLWPVPTASPQDVDDAVEAAQRALPAWSQASYDERTGLLEKFADLYLSRAGDFCQLLASECGRTVENAAIEVYWAAQWLRYPSSYKLPEEQIEDDTKTAIVTYEPLGVVAAICPWNSIGKIAPALATGNCVILKPSPFTPYTSLKLVELAQEVFPPSVIQVLSGGNGLGPALVKHPGIQKISFTGSTATGKQILKDGADTMKRITLETAGNNPAIILPDIDVTATVPHISGGLWFNAGQVCIAPRRLYIHADIFDVFVDALVETTKEATKEMTKIGPVQNELQFRKLVKTLDDAKSAGHDMATGGPLADAETGGFFLRPTIIKDASPESSIVSGEHFGPIVTCVRFSDADEAVHLANAGESGLAASIWTTNLTAAKALASRLDVGSVYINGPPQPDPRVPFGGHKQSGLGVEYGLQGLLSFCQTKAVYLYK
What is the function of this protein?
Aldehyde dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin lucilactaene and the lucilactaene-related compound NG-391 that act as cell cycle inhibitors with potent growth inhibitory activity against malarial parasites, moderate growth inhibitory activity against cancer cells, and no activity against bacteria and fungi (PubMed:32043422, PubMed:35484225).  LUC3 is important for lucilactaene biosynthesis and performs the oxidation of the C-20 alcoholic analog prelucilactaene G into a carboxylic derivative that has still to be identified (PubMed:35484225).  The pathway begins with the hybrid PKS-NRPS synthetase LUC5 which is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate prelucilactaene B.  Both the cytochrome P450 monooxygenase LUC2 and the hydrolase LUC6 function in parallel in modification of prelucilactaene B.  LUC6 may catalyze the 2-pyrrolidone ring formation to form prelucilactaene C from prelucilactaene B, followed by C-15 hydroxylation by the same enzyme to give prelucilactaene D, which is then converted to prelucilactaene E by epoxidation, and finally to prelucilactaene F by cyclization.  Prelucilactane D, prelucilactaene E, and prelucilactaene F can be converted to dihydrolucilactaene, NG391, and lucilactaene, respectively, via C-20 methyl group hydroxylation by the cytochrome P450 monooxygenase LUC2.  However, LUC2, unlike FUS8 in fusarin C biosynthesis, is not enough for the full oxidation of the C-20 methyl group into carboxylic acid, which is a prerequisite for the final methylation step.  The aldehyde dehydrogenase LUC3 is involved in the biosynthesis by further oxidation of the C-20 alcoholic analog prelucilactaene G into a carboxylic derivative.  This unidentified carboxylic derivative may be converted to demethyllucilactaene.  As the last step, the methyltransferase LUC1 methylates the hydroxyl group at C-21 of demethyllucilactaene to generate lucilactaene (Probable).
What are the official names of this protein?
Aldehyde dehydrogenase LUC3, Lucilactaene biosynthesis cluster protein 3.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NTR2_LEIIN
Sequence: MSAASKSIDVMLKPLLVGGRPISNRFVMAPLTRCRADDNHVPTAAMVKHYSDRASMGLIITEATQIQKGYSTFAHEGGIYDKEHVDGWRKVTDAVHDKGGIIFCQIHNGGRSTVPSNVDEGVRIVAPSAVAITGHKCAGSFARNGKTQPYPVPHAMAAEEIASYVNLYAAAARNAIAAGFDGVEVHGANGYLIDQFLKTSSNQRTDEYGGSIENRCRFLFEVLDAVIQAIGRERVGLRISPLNSFNDQSDEDPQALTRYICSQLNLRTIAFLDVMRGDFFSPARGADKWAREEYEGVLFTGMSFEIEEAAKAVESGAADAVVFGTKALANPDLVARAVAGAPLNKPDPATFYTTGEAGYNDYPFM
What is the function of this protein?
Acts as a FMN-dependent nitroreductase that activates anti-leishmanial bicyclic nitroaromatic prodrugs including delamanid, DNDI-VL-2098 and (R)-PA-824, forming toxic products that kill the parasites.
What are the official names of this protein?
Probable flavin mononucleotide-dependent alkene reductase, Flavin mononucleotide-dependent nitroreductase, NTR2.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: UBID_PSEAB
Sequence: MTFKDLRDFIAQLEQRGALKRIQVPISPVLEMTEVCDRTLRAKGPALLFEKPTGFDMPVLGNLFGTPERVALGMGAEDVGALREIGKLLAQLKEPEPPKGLKDAWAKLPMYRKVLSMAPKVLKDAPCQEVVEEGEDVDLGRLPVQTCWPGDVGPLITWGLTVTRGPNKERQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCQKHPGQPYPVAVALGADPATILGAVTPVPDTLSEYAFAGLLRGHRTELVKCRGSDLQVPASAEIVLEGVIHPGEMADEGPYGDHTGYYNEVDRFPVFTVERVTRRQKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDIDARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATHKWPGETSREWGRAIVKDEAVTRRIDALWSSLGID
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RASA1_HUMAN
Sequence: MMAAEAGSEEGGPVTAGAGGGGAAAGSSAYPAVCRVKIPAALPVAAAPYPGLVETGVAGTLGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVAGAAAGVAGAAVAGPSGDMALTKLPTSLLAETLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLDGPEYEEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQYTKTNDVR
What is the function of this protein?
Inhibitory regulator of the Ras-cyclic AMP pathway.  Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.
What are the official names of this protein?
Ras GTPase-activating protein 1, GAP, GTPase-activating protein, RasGAP, Ras p21 protein activator, p120GAP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_LISIN
Sequence: MRIRVPATTANLGPGFDSCGLALTLYLTLDIGEKADSWYIEHNIGGGIPHDETNVIIETALNLAPNLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESRGVLPETLPFKEAVKASSIANVMIAAILRNDMTLAGEMMERDLWHEKYRSKLVPHLTQIREVAKNNGAYAACLSGAGPTVLVFAPRDVADTLQTSLQTLEIDADVLLLDVEGSGAEVFR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_PYRIL
Sequence: MSAEVALVYRVLPESVEVDIEKLKNAVVNKLAPKYKVDKVEVEDVGFGIKALRFFIRMPESDEYSSDEVEELLRSVEGVGSYELEYFSRLSF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: FER_CAPAN
Sequence: MASVSATMISTSFMPRKPAVTSLKPIPNVGEALFGLKSANGGKVTCMASYKVKLITPDGPIEFDCPDNVYILDQAEEAGHDLPYSCRAGSCSSCAGKIAGGAVDQTDGNFLDDDQLEEGWVLTCVAYPQSDVTIETHKEAELVG
What is the function of this protein?
Delays the harpin-mediated hypersensitive response.
What are the official names of this protein?
Ferredoxin, chloroplastic, PFLP.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MF14A_MOUSE
Sequence: MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGTDLGTNTSPQHHFEQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLSLRSSSWRKHCGSHSHPHSTQAPGEAKEPLLQDTNV
What are the official names of this protein?
Hippocampus abundant transcript 1 protein, Major facilitator superfamily domain-containing 14A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YAGC_SCHPO
Sequence: MLLPIIMLTSGVANTVLSKYQDSIAEESEPIKSMAVLQSLNIFLGEACLWFYVLYKRHSQGPGYESLDHLPLKHKVFMALPAIMDICGSTLMNVGLLYTSASIYQMTRGSLIIFVALFATTLLKRTIGQLQWLSLSFVVLGVAIVGYSGSSSSIGSNPILGITAVLIGQFFLATQFTIEEYILSFIQVDPSELVAYEGTYGVFFVLLGMIISYYFIGSTTAGYHGWFDYSHVISRFNEVPALYVISGVILVSIAFFNVSGLAITKLHSATTRSLLDIARTFGIWIIAMAMGMESFHLLQFLGFVLLIYGIFTYHSIIKFPLAES
What are the official names of this protein?
Uncharacterized protein C12G12.12.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1545_PSEAE
Sequence: MLTLSGWITTQVPPSSRAAADAKAARTGTAEQAEDPAAGTDAADQHVQLSQAGRELAATMGVPVEEEDEDIPQELRPMVKMIRELKKKIEEKLRELQEAMRSSDPGAKEARVPELQKELQQLNSALQTATAAMASAIKEMGISDPALIMKVMGSR
What are the official names of this protein?
Uncharacterized protein PA1545.
Protein: RS20_MICAN
Sequence: MANTKSALKRVQISERNRLRNKAYKSAVRTLIKKCLVAVSAYGANPSPEGLESAQQALSEAYSKIDKAVKRNVLHRNNGARKKAGLAKALQKVSQAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.