PharMolix/UniProtQA huggingface dataset:
Protein: RS7_SYNJA
Sequence: MSRRNRAPRRDVPPDPKYGSRLVTMLIHKLMMRGKASLAARILYDALEIVRERTGQDPLPVLENAVRNATPLVEVKARRVGGATYQVPVEVRAERGTSLALRWLVTFSRTRPGRTMSAKLANEIIDAANETGNAIRRREEVHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SFSA_HAEIN
Sequence: MQLPALQSATLIRRYKRFLADIELPTGDVMTIHCANTGAMTGCGEKGDKIWYSHSDSQTRKYPHSWELTQLANGQLCCINTHRSNQLVFEALQNKQIKELAMYDEIYPEVKYGEENSRIDFLLKGEGLLDCYVEVKSITLVKGNLGMSPDAVTTRGQKHVRELLAMKKQGHRAVVLFAGLHNGFDRFKIAEYIDPEYDRLLKEAMEQGVEAYAYAGQFEISNEIPTALSLTESVSYIK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MIC12_YEAS2
Sequence: MSKLGPLARSVKWTLSVGVIGSVFYLYRYSNNGYFYDHDATWLKQDHQVQDLVDRKEVVPGETRNRKLVVTDDGTAWSRTMGESIKDIWNEQIRNSVDWIYSWGKN
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC12, Altered inheritance of mitochondria protein 5, mitochondrial, Found in mitochondrial proteome protein 51.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic12 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DCUP_HISS2
Sequence: MTVLKNDRYLKALLREPVDMTPVWMMRQAGRYLPEYKATRAKAGDFMSLCRNADLACEVTLQPLRRYDLDAAILFSDILTIPDAMGLGLSFGVGEGPKFARPIDNKSAVQNLPIPDPEQELQYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYSEPKILHLLLDKLADAVILYLNAQINAGVQAVMVFDTWGGVLGHREYLDFSLQYMHKIVDGLIRENDGYKVPVTLFTKGGGLWLEAMASTGCDALGLDWTVNLAEAKARVGHKVALQGNMDPSVLYASPARIEQEVQQILADFGQGSGHVFNLGHGIHQDVPEISPKVFVDAVHQYSIFYHQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_POLOR
Sequence: MTITRWLFSTNHKDIGTLDLIFGAWAGMVGTALSLLIRAELGQPGALMGDDQIYNVVGTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLTSSAVEAGVGTGWTVYPPLGGNLAHAGASVDLAIFSLHLVGVSSILGAINFITTIINMKPPSTSQYQTPLFVWSVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIVAYYSGKNEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGAIKWETPMLWALGFIFLLTVGGLTGIILANSSLDIMLHDTYYVVAHFHYVLSMGAVLAIMGGLVHWFPLFPGYTLHPTWTKIHFGVMFIGVNLTFSPQHFLGLAGMPRRYSDYPDAYTLWNSLSSIGSMISLTAVIMFLFILWEAFAAKREVQTVELTHTNVEWLHGCPPPYHTYEEPAFVQSPQARE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SUGP1_MOUSE
Sequence: MSLKMDNRDVAGKANRWFGMAQPKSGKMNMNILHQEELIAQKKREIEARMEQKARQSHVPSPQPPHPGEIADAHNSCISNKFANDGSFLQQFLKLQKAQTSTDSAPRAPPSMPTPSSLKKPLVLSKRTGLGLSSPTGPVKNYSHAKQLPVAHRPSVFQSPDDDEEEDYEQWLEIKVSPPEGAETRRVIEKLARFVAEGGPELEKVAMEDYKDNPAFTFLHDKNSREFLYYRRKVAEIRKEAQKPQAATQKVSPPEDEEAKNLAEKLARFIADGGPEVETIALQNNRENQAFSFLYDPNSQGYRYYRQKLDEFRKAKAGSTGSFPAPAPNPSLRRKSAPEALSGAVPPITACPTPVAPAPAVNPTPSIPGKPTATAAVKRKRKSRWGPEEDKVELPPAELAQRDIDASPSPLSVQDLKGLGYEKGKPVGLVGVTELSDAQKKQLKEQQEMQQMYDMIMQHKRAMQDMQLLWEKALQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGTEGQGIKNPVNKGATTIDGAGFGIDRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY
What is the function of this protein?
Plays a role in pre-mRNA splicing.
What are the official names of this protein?
SURP and G-patch domain-containing protein 1, Splicing factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROC_YERPA
Sequence: MAGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRRELDQVRILSGVFEGVTTGTSIGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQMGDVSCDLLDWDLVEQNPFFCPDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAVKGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMVPGQTINRQGEAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NHAD_ALKAM
Sequence: MQSLRCVSWLAGLLCLLFSTPVFAASAAPLDLTSSLVGFVCIAIFVVAYVLVMGEEKLHMRKSKPVLVAAGLIWILIGWVYISRDIPDVTEAAFRHNLLEFAELMLFLLVAMTYINALEERRLFDALRAWMIRKGFSYQNLFWITGFLSFFISPIADNLTTALLMCAVVMKVAEGDKRFINLCCVNIVIAANAGGAFSPFGDITTLMVWQAGLVRIDEFLVLFFPALVNYLIPAAVMSFFVEKRQPSAVYEDVELKRGALRILTLFLLTVATAVLCHSLLHLPPVLGMMMGLGYLQFFGYFLRMTLPGSLARKRAMAEREGDQEKLKRLGGVVPFDVFSRVSRAEWDTLLFFYGIVMCVGGLGFLGYLGLMSDLLYEGWNPTSANILLGVISAVIDNIPVMFAVLAMQPEMSHGHWLLITLTAGVGGSLLSIGSAAGVALMGQARGYYTFFGHLKWAPVIFIGYIASIAVHLWLNADLFHIYD
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.  Can also transport lithium.  Has a low antiport activity that functions over a large range of sodium concentrations.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaD, Sodium/proton antiporter NhaD.
What is the protein family that this protein belongs to?
Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y7K4_VACCW
Sequence: MIYLITNPPYVELEKYIKCFPLSVCIRLIKYLNLELMFNVTNSSPYNTPLFIFRFGYNSLSCS
What are the official names of this protein?
Uncharacterized 7.4 kDa protein.
Protein: RPIA_SHESR
Sequence: MTQDEMKKAAGWAALKYVEKDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDKLSVYVDGADEINGHMDMIKGGGAALTREKIVAAVAEKFVCIVDNTKQVDILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGVVTDNGNVILDVYNLKIINPKELEEKINAIVGVVTNGLFAKRGADVLLVGTPEGVKTFTA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: KATG_MYCA1
Sequence: MSSDTSASRPPQPDTGTASKSESENPAIPSPHPKSNAPLTNRDWWPNQIDVSRLHPHVAEANPLGEDFDYAEEFAKLDVEALKADVISVMTTSQDWWPADYGHYGGLFIRMSWHAAGTYRIHDGRGGGGQGMQRFAPLNSWPDNVSLDKARRLLWPVKKKYGNKISWADLIIFAGNCALESMGFKTFGFAFGREDVWEPEEILWGEEDEWLGTDKRYPGTGERELAQPYGATTMGLIYVNPEGPEGKPDPIAAAIDIRETFGRMAMNDEETAALIVGGHSFGKTHGAGDADLVGPEPEAAPIEQQGLGWKSSYGTGVGKDAITSGLEVVWTPTPTKWDNTFLETLYGYEWELTKSPAGAWQFTAKDGAGAGTIPDPFGGPGRAPTMLVTDISLRESPIYRDITRRWLDHPEELADAFAKAWYKLLHRDMGPVSRFLGPWVPEPQLWQDPVPPVDHPLVDDNDVAALKDKVLASGLSVPQLVKTAWSAAGSYRNTDKRGGANGGRLRLQPQRNWEANEPSELDKVLPVLEKIQQDFNASASGGKKISLADLIVLAGSAAVEKAAKDAGYEISVHFAPGRTDASQESTDVDSFAVLEPRADGFRNFARPGEKAPLEQLLLERAYLLGVTGPEMTVLVGGLRALGANHGGSKHGVFTDRPGALTNDFFVNLLDMGTEWKASETAENVYEGHDRATGALKWTATANDLVFGSNSVLRALAEVYAQDDNQGKFVEDFVAAWVKVMNNDRFDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PAAZ_ECOLI
Sequence: MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSAATGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEFALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNILLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQRHALQLACAGGGSLAGTLVTADPQIARQFIADAARTHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKPGDTIQVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD
What is the function of this protein?
Catalyzes the hydrolytic ring cleavage of 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA) via the open-chain aldehyde intermediate to yield 3-oxo-5,6-dehydrosuberyl-CoA.  The enzyme consists of a C-terminal (R)-specific enoyl-CoA hydratase domain (formerly MaoC) that cleaves the ring and produces the highly reactive 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde and an N-terminal NADP-dependent aldehyde dehydrogenase domain that oxidizes the aldehyde to 3-oxo-5,6-dehydrosuberyl-CoA.  Can also use crotonyl-CoA as substrate.
What are the official names of this protein?
Bifunctional protein PaaZ.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the aldehyde dehydrogenase family.
Protein: HYPB_SYNY3
Sequence: MCQNCGCSAVGTVAHSHHHHGDGNFAHSHDDHDQQEHHHHHGNYSKSPSQQTVTIEPDRQSIAIGQGILSKNDRLAERNRGYFQAKGLLVMNFLSSPGAGKTALIEKMVGDRQKDHPTAVIVGDLATDNDAQRLRSAGAIAIQVTTGNICHLEAEMVAKAAQKLDLDNIDQLIIENVGNLVCPTTYDLGEDLRVVLFSVTEGEDKPLKYPATFKSAQVILVTKQDIAAAVDFDAELAWQNLRQVAPQAQIFAVSARTGKGLQSWYEYLDQWQLQHYSPLVDPALA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.  Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.
What are the official names of this protein?
Hydrogenase maturation factor HypB.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.
Protein: BAT1_MOUSE
Sequence: MEETSLRRRREDEKSTHSTELKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTESVGPCLIIWAACGILATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYSGCKPPAVVVKLLAAAAILFITTVNALSVRLGSYVQNVFTAAKMVIVAIIIISGLVFLAQGNVKNFQNSFEGTQTSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQSQAVAVTFGDRVLYPASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLTPAPALIFYGIIAIIYIIPGDINSLVNYFSFAAWLFYGMTILGLVVMRFTRKDLERPIKVPLFIPIIVILVSLFLILAPIISEPAWEYLYCVLFILSGLIFYFLFVYYKFGWAQRISRPVTKHLQMLMEVVPPEKDPE
What is the function of this protein?
Associates with SLC3A1 to form a functional transporter complex that mediates the electrogenic exchange between cationic amino acids and neutral amino acids, with a stoichiometry of 1:1 (PubMed:10588648) (By similarity).  Has system b(0,+)-like activity with high affinity for extracellular cationic amino acids and L-cystine and lower affinity for intracellular neutral amino acids (By similarity).  Substrate exchange is driven by high concentration of intracellular neutral amino acids and the intracellular reduction of L-cystine to L-cysteine (By similarity).  Required for reabsorption of L-cystine and dibasic amino acids across the brush border membrane in renal proximal tubules (By similarity).
What are the official names of this protein?
b(0,+)-type amino acid transporter 1, b(0,+)AT1, Glycoprotein-associated amino acid transporter b0,+AT1, Solute carrier family 7 member 9.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: PEBB_TRIEI
Sequence: MTATNNIVNLYQPFLDYALTKLKEELELQPYPIPSGFEHKVAMTGKGKKQQEVQTTSYAHCSPKLRQIRAAHVQGGSALQVLNFVIFPHLNYDLPFFGADLVSLPGGHLIALDMQPLFRDNLQYQKKYTEPIWETFQKHQKYLPWGGDFPEEATPFFSPAFLWTRPQKTELVETRVFEAFKDYLQAYLIFVKQTEQITNSEKLAEIKEAQLRYLRYRAEKDPARKMLTRFYGHEWTEEYIHGFLFDLERKLALNPA
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: NORW_ECOLI
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLHLFPQTWVTDIDAEARVVKSQNNQWQYDKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGIQATLDRQRNIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNTDIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PECAS
Sequence: MPKIKTVRGAAKRFKKTAGGGFKRKHANLRHILTKKSTKRKRHLRPKGMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RTCB2_ENTDS
Sequence: MSSGYKPGKKRKVQPVQPIKKELVDFYGCQIPKEYEPYLQRTNVSLIIKKGFINGMKNDAEMFCNDDLFELLMNELLNEQPGASFSSCVRQTANVATLPGVIKSLAMPDAHSGYGFSIGGVAAMRLDDPNAVICPGGVGFDINCGVRLLRTNLDDKDIEPHLVELADALQKNIPSGVGTTSNQTLTEKEMNEIMNEGLEWLVKKDLAWKEDLVYCEENGRIINSDPHLVSQKARGRGRNQLGTLGSGNHYLEIQRVDEIMDMEAAKQMGISHIGQICIMIHCGSRGLGHQVCQDFVDLCVNQSNKNEVDIQLTGVPFQSDNGQKYFKAMNAAANYAFANRGMISYHVRCTFEQVFKKSPKDLDMHLVYDVCHNIAKEEIHLIDGNEIKCIVHRKGATRAFAPLNPVIPDAYKPIGQPAIIGGSMGTCSYMLVGTQEGMKKTFGSTCHGAGRKISRVKAMKDISSNSVVEEMKKKGIELRITDPKLAAEEADGAYKDVKEVVETCQSAGISKIVFKLKPLIVVKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog 2, 3'-phosphate/5'-hydroxy nucleic acid ligase 2.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: RL6_COXB2
Sequence: MVSRVAKNPIKIPTGVEVNVAGQQITVKGKLGTLTRVIHRAVKVTKTDAELQTICANDSPGSNALAGTARAVLANMVQGVHTGFQRKLVMVGVGYRAKAEDKKLNLTVGLSHPVNIEMPEGITVETPSQTEIIVKGADKQRVSQVAANIREIRPPEPYKGKGIRYDNERVILKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CM34_CONAA
Sequence: MMYKLGVLLIICLLLFPLTAVPQDGDQPADRPAERMQDDISFEHDRFFDPVKRCCKYGWTCWLGCSPCCG
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).
What are the official names of this protein?
Mu-conotoxin-like Am3.4, Conotoxin Ama1805, Conotoxin Ama1821.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TPP1_CANLF
Sequence: MRLRTCLLGLLALCVASKCSYSPEPDQQRTLPPGWVSLGRVDSEEELSLTFALRQQNVERLSKLVQAVSDPGSPHYGKYLTLEDVAELVRPSPLTFRTVQKWLSAAGARNCHSVTTQDFLTCWLSVRQAELLLSGAEFHRYVGGPTEIHVIRSLRPYQLPKALAPHVDFVGGLHRFPPTSSLRQRPEPQVSGTVGLHLGVTPSVIRQRYNLTAQDVGSGTTNNSQACAQFLEQYFHASDLAEFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHESQEPFLQWLLLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTEFMKAAARGLTLLFASGDSGAGCWSVSRRHQFRPSFPASSPYVTTVGGTSFQNPFRVTTEIVDYISGGGFSNVFPQPSYQEEAVVQFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNSVPIPWVSGTSASTPVFGGILSLINEHRLLSGLPPLGFLNPRLYQQRGAGLFDVTRGCHESCLNEEVQGQGFCSGPGWDPVTGWGTPNFPALLKALIKP
What is the function of this protein?
Lysosomal serine protease with tripeptidyl-peptidase I activity.  May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases.  Requires substrates with an unsubstituted N-terminus (By similarity).
What are the official names of this protein?
Tripeptidyl-peptidase 1, TPP-1, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I.
What are the subcellular locations of this protein?
Lysosome. Melanosome.
Protein: SUCC_AROAE
Sequence: MKIHEYQAKELLRKYGVVTPRGFHTVSVDGAVKAAEELGGKIWVVKAQIHAGGRGKGGGVKLARSLDEVRQHASDILGMQLVTHQTGPEGQKVRNLLIEEGADIQKEYYVAALTDRATQKVAIMASSEGGMDIEEVAHSTPEKILKEFVDPLVGLTDAQAENLARGIGVPEASVAKAVDALKRLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALYRHPEIVDFRDFDEEDADEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFGGIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKILAESGLPIIAADTMAEAATKIVAAVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS14Z_META1
Sequence: MARKSLMVKAERQPKFKVRKYTRCQICGRVHAVLRKYKICRICFRELAHEGKIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SYP_ECOSE
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_ACISJ
Sequence: MTTEKIDGVSVTTQANVYFDGKCVSHNLTYPDGTKKSVGVVLPATLTFGTGAPEIMECVGGSCEYQLDGTDAWVKVGAGEKFSVPGNSKFNIRVTEAFHYICHYG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: RPOZ_COXBU
Sequence: MARVTVEDCLEHVENRFDLVLKAAKRAHILELGGAEPMVPRDNDKPAVLALREIAAGYDVTREGQEQETEEVDVDRNVLAETAKMNKAVASQKESEV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: VGB_BACLD
Sequence: MQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLTESGDITEYTIPTESAGASIITSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFGIAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFPSFITRGADGALWFTQNQSGSIGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTAHARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFAEECGRIGKISIQN
What is the function of this protein?
Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
What are the official names of this protein?
Virginiamycin B lyase, Streptogramin B lyase.
What is the protein family that this protein belongs to?
Belongs to the Vgb family.