PharMolix/UniProtQA huggingface dataset:
Protein: MSRP_METCA
Sequence: MRKTSSPRIAPSEITPRDLYHDRRRFMQAAAGAAAAALWPHWLSAGEKLPGVRKTDHVLPDALTPFEDVAHYNNFYEFGTDKETPSRTAGSLKTRPWTVSVEGEVQKPKLFDVDDLLKLAPLEERIYRLRCVEGWSMVVPWVGFPLAELIKRVEPTGNAKFVEFITLYDPARMPGQKSSVLDWPYREALRLDEAMHPLTLLVFGLYGEVLPNQNGAPVRVVVPWKYGFKSAKSIVRIRFVEQQPVSTWTRAVPSEYGFYANVNPQVDHPRWSQAKERRLGEFFKRPTLMFNGYAEQVAHLYAGMDLKKFF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: SDS3_SCHPO
Sequence: MDVLSRVFDNEKEELDPLLNNPLTASEFRAKKAELEAELESIRNGTCKTLLDLADELRRSRDEELEIAERWRTFLVNRAQEEYEVEMKAAKEEYEYRCKTLKEMVLSHLNEKKRKIYEAKDMFDIGSESSTLLLHDASSQFIDRRKLRHRRNAGNQQNTQQLPSLNFFDDYLLFPTDETAVIPQSVKNAVRNSVNSVKPTSAEASLFSPLLSMANANPTNGRERDPRASERAERDREKAVEKGLSGATEEDIQSDLQLLKKELAKKK
What is the function of this protein?
Component of the clr6 histone deacetylase complex I responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
What are the official names of this protein?
Transcriptional regulatory protein sds3, Clr6 histone deacetylase complex I subunit Sds3.
What is the protein family that this protein belongs to?
Belongs to the SDS3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVC_ERWT9
Sequence: MAIILGIDPGSRITGYGVIRQTGRQLTYLGSGCIRTSVTDLPSRLKLIYAGVSEIITQFQPEYFAIEQVFMAKNADSALKLGQARGAAIVAAVNQDLPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHLSQNVTRLGEGNLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GEM_PONAB
Sequence: MTLNNVTMRQGTVGMQPQQQRWSIPADGRHLMVQKEPHQYSHRNRHSATPEDHCRRSWSSDSTDSVISSESGNTYYRVVLIGEQGVGKSTLANIFAGVHDSMDSDCEVLGEDTYERTLMVDGESATIILLDMWENKGENEWLHDHCMQVGDAYLIVYSITDRASFEKASELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRTCAVVFDCKFIETSAAVQHNVKELFEGIVRQVRLRRDSKEKNERRLAYQKRKESMPRKARRFWGKIVAKNNKNMAFKLKSKSCHDLSVL
What is the function of this protein?
Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane.  Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity).
What are the official names of this protein?
GTP-binding protein GEM.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RGK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HTPG_HAEIN
Sequence: MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETVAKLLRFASTHNDGSEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_BACC3
Sequence: MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_ESCF3
Sequence: MKLPIYLDYSATTPVDPRVAEKIMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_SINFN
Sequence: MTRSTSSAPSQRMLRVGEQVRAAITQVLQRGEVRDPLIEKTVISISEVRMSPDLKIATAYVTPLGVADHAAVIEALNKHAKFIRGRLGPQLRQMKYMPDVRFRDDTSFDNYQKIDALLRSPEVSRDLDPDTDDQE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGSA_BLOPB
Sequence: MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQTTSFGKFLDPVADKVMIVAALVLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRNGIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYVSVLLTFWSMCLYLYIVRYDLFNY
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_PARD8
Sequence: MSKLHIKKGDIVFVNAGEDKGKTGRVLQVLVKDNRAIVEGINVVSKHTKPNAKNPQGGIEKKEAPIHLSNLNVVDPKSGKATRIGRKLNEKGALVRYSKKSGEEIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CX05B_HUMAN
Sequence: MAKVTSEPQKPNEDVDEQTPSTSSTKGRKKGKTPRQRRSRSGVKGLKTTRKAKRPLRGSSSQKAGETNTPAGKPKKARGPILRGRYHRLKEKMKKEEADKEQSETSVL
What are the official names of this protein?
Uncharacterized protein CXorf51B.
Protein: TM156_RAT
Sequence: MTETAFLKLFVAIVITFILVLPEFFKTPKERTLELSCLEVCFLPNSTYPLSSFNFSSVAFLQPAEETQTIMGILPNHSSFQSFAEICQGITSGLPMCSLCLVCESKGDVDFTSQEQTSKGLVMRGSKEVKASDFYSPCEYFNVTVALLADPVKEDTTCTPEGHPGEAIALDEDPVREKSLNHTCRFMKNTDNCTHIFLHLEMDVKSVTCSMKITWYVLVLFVFMLGIIFIIYKILEEHRRVWRRQSHNYKSSSVLFRGHDSGKLSTLNVRVIPGYPWTIWTRDFDE
What are the official names of this protein?
Transmembrane protein 156.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VSP3_DEIAC
Sequence: MVLIRVLANLLILQLSYAQKSSELVIGGDECNINEHPFLVLVYYDDYQCGGTLLNEEWVLTAAHCNGKDMEIYLGVHSKKVPNKDVQRRVPKEKFFCDSSKTYTKWNKDIMLIRLDRPVRKSAHIAPLSLPSSPPSVGSVCRIMGWGSITPVEVTFPDVPYCANINLLDDVECKPGYPELLPEYKTLCAGILEGGIDTCGFDSGAPLISNGQFQGIVSWGGDPCAQPREPGVYTNVFDHLDWIKGIIAGNTDVTCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease Dav-KN, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_HASV1
Sequence: MASKSNKQVTVEVSNNGRSRSKSRARSQSRGRDKSVKITVNSRNRARRQPGRDKRQSSQRVRNIVNKQLRKQGVTGPKPAICQRATATLGTVGSNTSGTTEIEACILLNPVLVKDATGSTQFGPVQALGAQYSMWKLKYLNVKLTSMVGASAVNGTVSGVSLNPTTTPTSTSWSGLGARKHLDVTVGKNATFKLKPSDLGGPRDGWWLTNTNDNASDTLGPSIEIHTLGRTMSSYKNEQFTGGLFLVELASEWCFTGYAANPNLVNLVKSTDNQVSVTFEGSAGSPLIMNVPEGSHFARTVLARSTTPTTLARAGERTTSDTVWQVLNTAVSAAELVTPPPFNWLVKGGWWFVKLIAGRTRTGSRSFYVYPSYQDALSNKPALCTGSTPGGMRTRNPVTTTLQFTQMNQPSLGHGEAPAAFGRSIPAPGEEFKVVLTFGAPMSPNANNKQTWVNKPLDAPSGHYNVKIAKDVDHYLTMQGFTSIASVDWYTIDFQPSEAPAPIQGLQVLVNSSKKADVYAIKQFVTAQTNNKHQVTSLFLVKVTTGFQVNNYLSYFYRASATGDATTNLLVRGDTYTAGISFTQGGWYLLTNTSIVDGAMPPGWVWNNVELKTNTAYHMDKGLVHLIMPLPESTQMCYEMLTSIPRSRASGHGYESDNTEYLDAPDSADQFKEDIETDTDIESTEDEDEADRFDIIDTSDEEDENETDRVTLLSTLVNQGMTMTRATRIARRAFPTLSDRIKRGVYMDLLVSGASPGNAWSHACEEARKAAGEINPCTSGSRGHAE
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes (PubMed:22743104).  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: NQRF_NEIM0
Sequence: MEIILGIVMFTVIVLVLALMILFAKSKLVSEGDITIKVNGEKELTMPAGGKLLGALANEGIFIPSACGGGGSCGQCRVVVKSGGGDILPTELSHISKREAREGCRLSCQVNVKTDMDIEVPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAPPHTVAYKDFDIPEEYHEDWDKYNLWQYVSKVDEPILRAYSMASYPEEKGIIMLNVRIATPPPRVPDAPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLNSKRKITFWYGARSKREMFYVEDFDQLAAEFPNFTWHVALSDPLPEDNWDGYTGFIHNVVYENHLKNHEAPEDCEFYMCGPPIMNQSVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPOB_STRZP
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MOAA_PAENI
Sequence: MPAARPAGAGVGLVDRYGRRATDMRLSLTDKCNLRCTYCMPAEGLEWLSKQAVMSASEIVRIVGIGVGRLGVRELRLTGGEPLVRHDLVDIIAELRRNHPELPISMTTNGVGLAKKVAPLKAAGLTRINVSLDSLHEETFTKLTRRPFLDQVLAGVDAAWAAGLGPVKLNAVLMRGINDAEAPSLLAWAVERGYELRFIEQMPLDADHGWTRRNMITAAEIRDLLSTDFVLTPDPRARDGAPAERFEVRRRVAGSGAGLGPVLGTVGIIASVTEPFCSDCRRTRITAEGRIMSCLFSREEFDLLVLLRSGASDDDLARRWQDAMWLKPKAHGMDHVGLDAPDFVQPDRSMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ZN514_HUMAN
Sequence: MTFEDVAVEFSQWEWGQLNPAQKDLYREVMLENFRNLAILGLLVSKPYVICQLEEGGEPFMVEREISTGAHSDWKRRSKSKESMPSWGISKEELFQVVSVEKHIQDVLQFSKLKAACGCDGQLEMQQIKQERHLKQMSTIHKSATTLSRDYKWNGFGRSLGLRSVLVNQHSILMGEGSYKCDTEFRQTLGGNNSQRTHPEKKSCKCNECGKSFHFQSELRRHQRCHTGEKPYECSDCGRAFGHISSLIKHQRTHTGEKPYECSECGRAFSQSSSLVLHYRFHTGEKPYKCNECGRAFGHTSSLIKHQRTHTGEKPYECRECGRTFSQSSSLIVHYRFHTGEKPYKCNKCGRAFSQSSSLTQHYRFHTGEKPYKCNECGRAFAHTASLIKHQRSHAGKKTL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 514.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WDY_DROAN
Sequence: MPMLIQKSEVEYQTISSTQSHLAEEQSERLHRCISKEQLEKLHEAFLNAPERQVGIDDLRVMLEDLDITFNDSMYTRLFLKINQNRDFRVDWNEFVSYLIFGFQEEDPSSQKESLILPISVPPMVRKSEHRSAICCLALLKAKSDQVPIEEVTETVNFSFGGEDSPEASGMWVTASHEGMMRFWTSHMEPIRTASSESIHLNYAFYNNGKVHSKLILGDYAGNVRILSYSPHLRGPFQAKPGAALIEVVWSDVLKGKIPQFVPKEYISLHNEMISCVYFSLHMNALFASAEYRNTKKYRGRCPGMIMVTYDERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEENKVYSVDYQKIIKVWDLQEHTLLQTYGDLVRLIHHSETDLTYYYHSHLRELVVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIMPDQEVTSVIWVVDRILAMGWDRQVTEFNDVVGREYGDPKKWPKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMDPTRFIELKLTAEEEKSLRRSKRLASRPTHTGIHGLQMSRAGRSTVTNRPEDNRDYGANIPISVQAVLFLQTRPQTLKHGSVFISLDTGYIQVYSHHQRGGYMMEFLAVHKTGDCVLTMCTDRKNRFLYTGTAFGYVKIWYIVNFCVPASEKTHVCMPKLRLEFIFLRKELFLTRAKRAIRNQPEPLLVSSYKGHLKAINSIAFINLPKIVFTGSHDYSCRLWTQGGRYLGTLGTVLPWSKLTPFERAGDDSQTYRMPPDIKKVASSTTLKVISGLQAERMVKRQEGKVTEDRDEDTAQTEDVTELKRLLDSPIKEPILGKHFELPGRTVLDQHIELDTSQSYIAVYTHLKVHSTEMLERLPTPAVIGKVQAENYLHHYVPVEGKVDISGSSLNIKQPTRRRSGKTHDPRNIRTAKARLDIGMGLSSSHASQQ
What are the official names of this protein?
WD repeat-containing protein on Y chromosome, WD40 Y.
Protein: GRPE_GLAP5
Sequence: MTNQTEKEQVEQDVSQATELAQEAQEAQTQDVEPELQQNNEIDPLEEAIARVQELEAYIAEADKREQDIQLRARAEVENIRRRAEQDVEKAHKFALEKFSKEMLTVVDNLERGLQALEGVDESVKSGVELTHKGLVSTLNNFGVEAVGVVGEAFNPELHQAISMQPAEGIEANHISVVLQKGYTLHGRVIRPAMVMVAS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_THIDA
Sequence: MSIADNKKAFHDYFIEERFEAGLVLEGWEVKAIRAGRVQLKEAYVVVKNGAVYLIGCHISPLPTASTHIHPDPTRSRKLLLHAAEINKLIGKTERAGFTLVPLDMHYSKGRIKLEIGLAKGKKQHDKRAAEKDREWQREKQRLVRSAQH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HBB_ALCAA
Sequence: MLTAEEKAAVTAFWGKVKVDEVGGEALGRLLVVYPWTQRFFEHFGDLSTADAVMHNAKVKEHGKRVLDAFSEGLKHLDDLKGAFAKLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKEFTPELQADYQKVVTGVANALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DXS_ALTMD
Sequence: MSLDLQHYPTLALAQTPDKLRQLPQDKLRELADELREYLLNSVSQTSGHFASGLGTVELTVALHYVYNTPFDRLLWDVGHQAYPHKILTGRAERMSTIRQKNGLHPFPWPPESEYDTFAVGHSSTSISAALGMAVAAEKEGKDRKVVSVIGDGAMTAGMAFEALNHAGDIKKDMVVVLNDNEMSISENVGALNSHLARLLTGNFFNSIRDGGKKLLSNVPPIKEFASRAEEHLKGMVVPGTIFEELGFNYIGPIDGHDVNAVVDTLRNMRNFDGPQLLHVVTKKGKGYAVAEEDPIKFHAVPKFNPADNALPKSKPSAPTYSAIFGQWLCDMAAQDPKLMAVTPAMREGSGMVEFSQRFPEQYFDVAIAEQHAVTFGAGLAKDGMNAVVAIYSSFLQRAYDQLIHDVAIQDLPVLFAIDRAGIVGADGPTHQGAFDIAFLRCIPNMVVMAPSDENECRQMLYTGHKLQKPAAVRYPRGAGMGVTPDEAMTALEIGKSRTCRETAKDKSESVAILNFGCLLPYALEAAVAIDATVIDMRFIKPLDGDAVLKAANEHSALITLEDGCIMGGAGSAVLEHLQQNGVLKAVKMLGLPDSFILQGTQQEMYKEHGLDAEGIIAAAKSLIG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: XPOT_SCLS1
Sequence: MDAQIEKAIEIAWDPRSDQNLKEQAVQYLTQVRGDSSSLQACLNLFTRDPKAAEVVRLVSLDIVNNAIQTQHIDDQSLRGLKEQLHDYVRRTYASGNEVDPPALQNKLTQTLTFLFSSLYKEGWESFIRDFLSFTGHQNGTVDNLPGVVLYLRLLSSIHDEIADLMIVRAGGETKRNVELKDLVRARDVQIVAGSFQHILTYWQGNNDAIVEMTLKVIGKWVSWIDISLVVNQDILNLLFPLVGRNPNGGEDKVKDAAIDCFTEIVAKKMKPSDKIGMILFLNLGEVVSQLIASPALHDLRNTSSYDTDLAEAVAKLVNNVVSDLVKILEDTKVEPEVRAQAEQSLQTFLPLLLRFFSDEYDEICATVIPSLTELNTFLRKAQPLPPAYSAMLTPILNAIIQKMRYDDTSSYADEDELTDEAEFQELRKRLQVLQKTIAAVDEALYVDVLSNVIGNTFQRLDQQNGQIDWRDLDLALHEMYLFGELTLVNGGLYAKSQPSSIAAERLIVMMSKMVESGIASFNHPAISLQYMEICVRYCSFFENQTQYIPQVLEQFVGFVHHNHSRVRIRSWYLFHRFVKHLRGQVGNVAETIIQSISDLLPLKAEVPKESDDDMSSEDGSHDAADVAFNAQLNLYEAIGCISSTTSTPIEKQAIYARTIMNPLFSDVQRHLEQAKSGNAQAVLQIHHIIFALGSLAHGFSDWSPGEGKRAGQAPAKEITIEFSRAAEAILFALEALKSSSEIRNAARSSFSRLMGVMGVAMLPLLPRWIDGLLTQSSSKEEIGMFLRLLDQVVFGFKKDIHEVLNSLLTPLFQRVFASLSEPVTGTDDGIQLAELRREYLSFVTVILNNELGSVLVSEQNQAFFDPLVQSVTTLAKTVTNETGNLAASKIAFSVMTKMAELWGGPTIATPGQPITSSVQPQPTFPGFDTFLIERFHPVCWEVLREPHFRPMVDAQSKSVLNELAGLEHVIYMKTGNMFVEHLQGNFFPSMGVDGSGFIKSMVESPERKGLATFLQNWLKGRA
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: F166B_BOVIN
Sequence: MASTFIPGLNPQNPHYIPGYTGHCPLLRFSMGQTYGQMTGQLLRGSPGLAWPPAHRTLLPPIQPPRSPEPRRRSLPVRPGHERLSSSMVPGYTGFVPQAQFIFAKNCSQVWAEALNGFTQRNGGQGSQELPKEAKGEKDVEKDQEPKPEVEKEPELGQEAEQASPYSMDDRDPRKFFMSGFTGYVPRARFLFGSSFPVLSNQALQEFGEMKSPGRSQKDPKHLPALSRTYPQHLGLLPKYGGYVPGYKFQFGRTYGHLTQDALGLSTLQKQLLV
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Protein FAM166B.
What is the protein family that this protein belongs to?
Belongs to the UPF0605 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.