PharMolix/UniProtQA huggingface dataset:
Protein: GSA_PECAS
Sequence: MNKSESLYAAAQQLIPGGVNSPVRAFNGVGGTPLFIERADGAYLYDVDEQAYIDYVGSWGPMVLGHNHPSIRDAVIAAAERGLSFGAPTEMEVQMARLVTSLVPSMDMVRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFARHTLTCVYNDLSSVRTTFEQYPDEIAAIIVEPVAGNMNCVPPLPDFLPGLRALCDEFGALFIIDEVMTGFRVALAGAQSHYGVVPDLTCLGKIIGGGMPVGAFGGKREVMQALAPTGPVYQAGTLSGNPIAMAAGFACLTEVAKPGVHEKLTALTNQLADGLLAAAKAENIPLVVNQAGGMFGLFFTDAESVTCYQDVMKCDVERFKRFFHMMLEEGIYLAPSAFEAGFMSLAHTPQDIERTIEAAQICFSRL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_CHLTE
Sequence: MSQVDKTARRQKIKARSRAVVRGTQERPRLCVFRSLSQIYAQLIDDESGKTLMAASSMSKENAGLTGTKSEVSAAIGKQIAEKALAQGISRVVFDRNGFRYHGRIKALADGAREAGLIF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DKC1_RAT
Sequence: MADAEAAMTFPKKHKKKKERKPLPEADVAEIQHAEDFLIKPESKAAQLDTSQWPLLLKNFDRLNVRTTHYTPIPCGSNPLKREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGVVRLHNAIEGTAQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESRVVEYDPERRLGVFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVVGERDHMVTMHDVLDAQYLYDHHRDESYLRRVVFPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGLLRYEDGIEVNQEVVVITTKGEAVCVAIALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKQLIKQGLLDKHGRPTDGTPASWTRDYVDYSDSSKKATAAEATPGPGVTADAASIVKRKRDSDSDADEATPTTTPRVKKEKKKKKEKADGGEEAAEDGDGDATRKKKKKKARAAEELSG
What is the function of this protein?
Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:12446766).  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (By similarity).  Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs (By similarity).  Required for ribosome biogenesis and telomere maintenance (By similarity).  Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit DKC1, Dyskerin, Nopp140-associated protein of 57 kDa, Nucleolar protein NAP57, Nucleolar protein family A member 4, snoRNP protein DKC1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Protein: HIS6_ACISJ
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNAQGADELTFLDITATSDERDLILPIIEAVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAAIANPDVISQASAKYGAQCIVVAIDAKRRQGAEVAERGEGWDVYSHGGRKNTGLDAVQWAVEMARRGAGEILLTSMDRDGTKSGFDLQLTRAVSDAVGVPVIASGGVGNLDHLADGVQQGGADAVLAASIFHYGEFTVRQAKERMRERGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T1SA_ECOLX
Sequence: MSVEKLIVDHMETWTSALQTRSTAGRGSSGKIDLYGIKKLRELILELAVRGKLVPQDPNDEPASELLKRIAAEKAELVKQGKIKKQKPLPEISEEEKPFELPDGWEWTTLTRIAEINPKIDVSDDEQEISFIPMPLISTKFDGSHEFEIKKWKDVKKGYTHFANGDIAIAKITPCFENSKAAIFSGLKNGIGVGTTELHVARPFSDIINRKYLLLNFKSPNFLKSGESQMTGSAGQKRVPRFFFENNPIPFPPLQEQERIIIRFTQLMSLCDQLEQQSLTSLDAHQQLVETLLGTLTDSQNVEELAENWARISEHFDTLFTTEASVDALKQTILQLAVMGKLVPQDPNDEPASELLKRIAQEKAQLVKEGKIKKQKPLPPISDEEKPFELPEGWEWCRLGSIYNFLNGYAFKSEWFTSVGLRLLRNANIAHGVTNWKDVVHIPNDMISDFENYILSENDIVISLDRPIINTGLKYAIISKSDLPCLLLQRVAKFKNYANTVSNSFLTIWLQSYFFINSIDPGRSNGVPHISTKQLEMTLFPLLPQSEQDRIISKMDELIQTCNKLKYIIKTAKQTQLHLADALTDAAIN
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates A-2 on the top strand and A-3 on the bottom strand of the sequence 5'-GAGN(7)GTCA-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated (PubMed:2642743, PubMed:6325176, PubMed:12654995).  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (By similarity).
What are the official names of this protein?
Type I restriction enzyme EcoAI specificity subunit, S protein, Type I specificity subunit S.EcoAI, S.EcoAI, Type-1 restriction enzyme EcoAI specificity subunit.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: ELAP1_HUMAN
Sequence: MAEPGHSHHLSARVRGRTERRIPRLWRLLLWAGTAFQVTQGTGPELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPIKGTECSFSCNAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSANMELDDSAAESTGNCTSSKWVPRGDYIASNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWTKVPKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANSYSNKGETSCHQCDPDKYSEKGSSSCNVRPACTDKDYFYTHTACDANGETQLMYKWAKPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNNSTCQPCPYGSYSNGSDCTRCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAAGASDNDFMILTLVVPGFRPPQSVMADTENKEVARITFVFETLCSVNCELYFMVGVNSRTNTPVETWKGSKGKQSYTYIIEENTTTSFTWAFQRTTFHEASRKYTNDVAKIYSINVTNVMNGVASYCRPCALEASDVGSSCTSCPAGYYIDRDSGTCHSCPTNTILKAHQPYGVQACVPCGPGTKNNKIHSLCYNDCTFSRNTPTRTFNYNFSALANTVTLAGGPSFTSKGLKYFHHFTLSLCGNQGRKMSVCTDNVTDLRIPEGESGFSKSITAYVCQAVIIPPEVTGYKAGVSSQPVSLADRLIGVTTDMTLDGITSPAELFHLESLGIPDVIFFYRSNDVTQSCSSGRSTTIRVRCSPQKTVPGSLLLPGTCSDGTCDGCNFHFLWESAAACPLCSVADYHAIVSSCVAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNQKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIKSFTSKRTPDGFDSVPLKTSSGGLDMDL
What is the function of this protein?
May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway (PubMed:21072319).  May play a role in apoptosis and cell proliferation through its interaction with HSPA5 (PubMed:26045166).
What are the official names of this protein?
Endosome/lysosome-associated apoptosis and autophagy regulator 1, Estrogen-induced gene 121 protein.
What is the protein family that this protein belongs to?
Belongs to the ELAPOR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: S6A18_HUMAN
Sequence: MAHAPEPDPAACDLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPWSSCPPDLNRTGFVEECQGSSAVSYFWYRQTLNITADINDSGSIQWWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYLFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVEAVITPLLDVGVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASPNLLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLFWKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQLLTRRRRTWRDRDARPDTDMRPDTDTRPDTDMRPDTDMR
What is the function of this protein?
Does not show neutral amino acid transporter activity.
What are the official names of this protein?
Inactive sodium-dependent neutral amino acid transporter B(0)AT3, Sodium- and chloride-dependent transporter XTRP2, Solute carrier family 6 member 18, System B(0) neutral amino acid transporter AT3.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYR_ECOSE
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JTB_MOUSE
Sequence: MLAGAGRRGLPRAGHLCWLLCAFTLKLCEAEAPVREEKLSVSTSTSPCWLAEEFVVTEECTPCSNFQIKTTPECGSTGYVEKITCSSSKRNEFKSCRSALLEQHLFWKFEGVVVAVALVFACLVIVRQRQLDRKALEKVRKQIESI
What is the function of this protein?
Required for normal cytokinesis during mitosis.  Plays a role in the regulation of cell proliferation.  May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.  Increases AURKB activity (By similarity).  Inhibits apoptosis induced by TGFB1.  Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
What are the official names of this protein?
Protein JTB.
What is the protein family that this protein belongs to?
Belongs to the JTB family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Mitochondrion. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase (By similarity).
Protein: ACPS_STAES
Sequence: MIYGIGIDLIEIERIKNLQNQTKFIERILTIEERDKLNQYTHEQRRLEFLAGRFTVKEAFSKALGTGLGKSVSFQDINCYNDALGKPCIDYPGFYTHVSITHTENYAMSQVILEKNE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPTA_METLZ
Sequence: MSLPDVQSTAPDVRISLTRVGVKNVRKLVEVGRPGKTRPAIFISEFDVFVDLPSSLKGANLSRNFEVIDEVLQQATSGDVKGIEDVCGIVSRKLLDHHEYADRTEVFMRSFYMMNRETPVSKTSCQEVINVYAHAVAQRTNGKPMVRKSVGAEVTGITACPCAQNIMKDHAMHVMEQLEIPEDKISAFFNEIPMASHNQRGRGFLCVETDGDIIVPLEKIVTVLKESMSAKIYELLKRGDESYVVMAAHKNARFVEDCVREMARRVVSTFGDLPGDTHITIRQTNEESIHQHDAYAERKATLAELRDELSI
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: EDSBC_ARATH
Sequence: MAFEALTGVNGDLVTISWMASKGANQTEHYLKEEVGGTVFFAFRASFSSEDLFATENTSPFGEIKMKRNQFPCMRSIGNDVDTTVNEAFLKSLEVLIGPRTSFHASVQSAVDRKQQVVFTGHSFGGATAILATVWYLETYFIRDAYAAPEPRCVTFGAPLVGDYIFKHALGRENWSRFFVNFVTRFDIVPRIMLARKTTIEQTLSYVLGKLDSTRAPIHESDQVITEFYTRVMRDTYTVASKAVCQLIGNGEAFLETLSSFYELSPYRPVGTFVFSTQKRLVVVNNSDAILQMLFYTCQSNDEQELSVIPFLSIRDHHGYEELVQSIGIKLLNHLDLHNPLLDGENSIGSALDDLGMSTRARQCIHAALEAEKQRVENQKKIETKRDQIVERLTWIVEVYKPKCQAHKNGYYDSFKDSNEENDFKANVKRVELAGIFDEVLGLVKKGQLPDGFEGSRGWINLATQYRRLIEPLDISNYHGQLKNEDTGPYMLHGRPSRYKYAQRGYEHDILKPTGMIAKDVFWSKVNGLNLGLQQDIQEILKNSGSECGSCFWAEVEELKGKPYEEVQVRFKTLEGLLEGWIKDGEVDEKEIFLEGSTFRKWWNTLPDSHKIHAPLYPRERMMDETRAT
What is the function of this protein?
Acts as a second functional copy of EDS1.  Can mediate HRT-mediated resistance to turnip crinkle virus.
What are the official names of this protein?
Protein EDS1B, Enhanced disease susceptibility 1 protein B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Found in both the nucleus and diffuse in the cytosol when associated with PAD4 and only in the nucleus when associated with SAG101.
Protein: RIMP_ACIF5
Sequence: MVNVEDRLYEGIAQQAGIAGCTLVDARMVRTGRAVALQVFIEKDETTAVTIEDCAAVSRQLSLWLDVENPIHGAYRLEVSSPGLDRPLKNLHDFERFKGSQAEIHLHGLTQGRRRLQGELLGVEDQKIVLKNAEGRWTFALDDIHKARLVPQW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3AR_MACFA
Sequence: MAPFSAETNSTDLLSQPWNESPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTVWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAITLDRCLVVFKPIWCQNHRNVGTACTICGCIWVVAFVMCIPVFVYREIFTTDNHSKCGYKFDLSGSLDYLDFYGNPLENRSLENIFQLPGEMNDRLDPSSFQANDHPWTVTTAFHTQTFQRPSADSLPKDSASHSPYSNVFKPAGVASPKIPSGFPIEGHKTSPLDDSDAFLSTHLKLFPSAASNSLYEYELPQDFQDYYSLGQFTYDNQVSTPLVAITITRLVVGFLLPSVIMIACYSFIVLRMQRGRFAKSQGKTLRVAVVVVTVFLVCWAPYHISGVLSLFTDPETPLGKTLMSWDHVFTALASANSCFNPFLYALLGKDFRKKARQSIQSILEAAFSEELTHSTHCSSNNVFSERNSISTTV
What is the function of this protein?
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a.  This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).
What are the official names of this protein?
C3a anaphylatoxin chemotactic receptor, C3AR, C3a-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAT_ARCFU
Sequence: MPLIKTPPPHGGKLVERVVKKRDIAEKMIAGCPTYELKPTTLPDGTPIRHVYREIMSVCYGFFSPVEGSMVQNELERVLNERRLLSEWIFPYPILFDISEEDYKALDVKEGDRLLLMLKGQPFATLDIEEVYKIDPVDVATRTFGTPEKNPEVVREPFDDKHPGYVIYKMHNPIILAGKYTIVNEPKFKEPYDRFWFPPSKCREVIKNEKKWRTVIAHQTRNVPHVGHEMLMKCAAYTGDIEPCHGILVNAIIGAKRRGDYPDEAILEGHEAVNKYGYIKPERHMVTFTLWDMRYGNPIESLLHGVIRQNMGCTHHMFGRDHAAVGEYYDMYATQILWSQGIPSFGFEAPPNEVDYGLKIIPQNMAEFWYCPICQEIAYSENCGHTDAKQKFSGSFLRGMVAEGVFPPRVVMRPEVYKQIVKWWKVYNYPFVNRKYLELKNKELEIDLPAMEVPKA
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: ATPA_NYMAL
Sequence: MVTIRAEEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFAEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEILASEYRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVTTFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRQRHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKPSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSSPLAVDEQIVTIYTGTNGYLDQLEIGQVKKFIVQLRTHLRTNKPQFQEIISSTKVFTEQAEALLKEAIQEQMELFLLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MURG_VIBA3
Sequence: MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVSKLIKAPFQIINAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNPVREDVVALADPEQRMAERDGDIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVTEFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAALMIEQPQLTADKLANTIAQLDRNELKMMATKARQAAKLDADVTVAEAIKALAK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LOLA_CHRSD
Sequence: MRAFKWALAIGATLALPLTAQAQTGGAERLAALLESVTSYSADFDQQILDGGGQRLQEAEGHMWLSRPGKFHWEVEAPYRQVVVSDGDKVYLYDPDLEQVSVRPLDTRVTHTPALLLSGSADALTENYAVESRQGDDEETFTLTPKSPDTLFESLQLTFENERLEGLQMEDSTGQRTAIAFDDIEVNGDIDASRFTFEIPEGADVIREGG
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CPAM_ASPOZ
Sequence: MKIGLLVLRGDPVEGPSVVDLSSYIPPSRHQFETRYISKSEAEAGIDRICKDEFDMCLNYMTVESCDDVSTVAAITRYLEAKDITLLNSPCLTHITDAGEETRRFRIPIKAHELNLEDLRGKKWLTLAMDMGREAMSFSPGQFTSSMCLDQEDLHSTSTDFTWVTEDPLKSMLRSMALDVLKASSGGFVCVEASLQAQADSMYLEGLLCTPRAFYREKHSTYEDVVIEQEFPGGHLAFLDMLITSKQIRSGQDHARNQHLAGVYDSFAPRYHAARANTGLSRMQEDMSRDYDFSGTVLDLACGNGEFGATLHENGVSAKVTGIDVSEGMTRSSYIQDHYERPLLIGPMDELIMGMPEFDHVSVTAIHEDLSDAYIEDMKKRNGELCSNFNHISTLEEFGVPNGWQQVLMQRFPLYENPNLGETVYGFAIRFERA
What is the function of this protein?
Putative methyltransferase; part of the gene cluster that mediates the biosynthesis of the fungal neurotoxin cyclopiazonic acid (CPA), a nanomolar inhibitor of Ca(2+)-ATPase with a unique pentacyclic indole tetramic acid scaffold (PubMed:21608094).  The hybrid two module polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) cpaS incorporates acetyl-CoA, malonyl-CoA, and tryptophan (Trp) and utilizes a C-terminal redox-incompetent reductase domain to make and release the tryptophan tetramic acid, cyclo-acetoacetyl-L-tryptophan (c-AATrp), as the first intermediate in the pathway.  CpaS catalyzes a Dieckmann-type cyclization on the N-acetoacetyl-Trp intermediate bound in thioester linkage to the phosphopantetheinyl arm of the T domain to form and release c-AATrp (PubMed:21608094, PubMed:19663400).  CpaD then regiospecifically dimethylallylates c-AATrp to form beta-cyclopiazonic acid.  CpaD discriminates against free Trp but accepts tryptophan-containing thiohydantoins, diketopiperazines, and linear peptides as substrates for C4-prenylation and also acts as regiospecific O-dimethylallyltransferase (DMAT) on a tyrosine-derived tetramic acid (PubMed:21608094, PubMed:19877600).  The beta-cyclopiazonate dehydrogenase cpaO then carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate (PubMed:21608094).  Finally, the cytochrome P450 monooxygenase cpaH mediates the conversion of CPA into the less toxic 2-oxocyclopiazonic acid, the end product of the CPA pathway in A. oryza (PubMed:21608094).  The putative methyltransferase cpaM does not seem to be involved in CPA nor 2-oxocyclopiazonic acid biosynthesis (PubMed:21608094).
What are the official names of this protein?
Putative methyltransferase cpaM, Cyclopiazonic acid biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: PSBH_SPIMX
Sequence: MATKINDDILSTPGKKTSVGDILKPLNSEYGKVAPGWGTTVLMGVFMALFAVFLVIILEIYNASVLLDGIPVSWNSLS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: OR33B_DROME
Sequence: MDLKPRVIRSEDIYRTYWLYWHLLGLESNFFLNRLLDLVITIFVTIWYPIHLILGLFMERSLGDVCKGLPITAACFFASFKFICFRFKLSEIKEIEILFKELDQRALSREECEFFNQNTRREANFIWKSFIVAYGLSNISAIASVLFGGGHKLLYPAWFPYDVQATELIFWLSVTYQIAGVSLAILQNLANDSYPPMTFCVVAGHVRLLAMRLSRIGQGPEETIYLTGKQLIESIEDHRKLMKIVELLRSTMNISQLGQFISSGVNISITLVNILFFADNNFAITYYGVYFLSMVLELFPCCYYGTLISVEMNQLTYAIYSSNWMSMNRSYSRILLIFMQLTLAEVQIKAGGMIGIGMNAFFATVRLAYSFFTLAMSLR
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to pentyl acetate and pyrazines.
What are the official names of this protein?
Odorant receptor 33b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.