PharMolix/UniProtQA huggingface dataset:
Protein: CC115_BOVIN
Sequence: MASRDLRAEVDFVLLQLLGDLEQLEAKRQALNARVEEGWLSLSKARYAMGAKSVGPLQYASHMEPQVRVGTSESQDGLQKFWMVRAGTQTPEEVGSREAALRRRKGLPRTPEPDSSPAPQNPLKWFGILVPHSLRQAQASFREGLQLAADMASLQSRITWGQSQLQELQEKLKQLEPRAP
What is the function of this protein?
Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis.  In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.  Necessary for endolysosomal acidification and lysosomal degradation (By similarity).  May be involved in Golgi homeostasis (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 115.
What are the subcellular locations of this protein?
Endosome. Lysosome. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle, COPI-coated vesicle. Endoplasmic reticulum.
Protein: THIG_SHEON
Sequence: MLTVAGVEFESRLFTGTGKFSSSQLMLEAINASKSQLVTVSMKRIDLKTGADDLLTPLRQAGVRLLPNTSGARNAKEAIFAAELAREMLGTQWIKLEIHPDPKYLMPDAVETLTAAQILCERGFIVMPYVHADPVLCRRLEDVGCAAVMPLASPIGTNQGLVTEPFIKMIIEQARVPVVIDAGIGAPSHAAHAMELGADAVLVNTAIASSASPIEMALCFRDAVNCGRRAFEAGLGRVQTQAVHTSPLTGFLQQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCN4A_MOUSE
Sequence: MASSSLPTLVPPGPHCLRPFTPESLAAIEQRAMEEEARLQRNKQMEIEEPERKPRSDLEAGKNLPLIYGDPPPEVIGVPLEDLDPYYSDKKTFIVLNKGKAIFRFSATPALYMLSPFSIVRRVAIKVLIHALFSMFIMITILTNCVFMTMSNPPSWSKDVEYTFTGIYTFESLIKMLARGFCIDDFTFLRDPWNWLDFSVITMAYVTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPPPMNDTNTTWYGNDTWYGNDTWYGNDTWYGNDTWNSQESWVSNSTFDWEAYINDEGNFYFLEGSNDALLCGNSSDAGHCPEGYECMKAGRNPNYGYTSYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVAMAYAEQNEATLAEDQEKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEEADGDPTHSKDCNGSLDTSGEKGPPRPSCSAESAISDAMEELEEAHQKCPPWWYKCAHKVLIWNCCAPWVKFKHIILLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLSVGNLVFTGIFTAEMVLKLIAMDPYEYFQQGWNIFDSFIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIASDCSLPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMVIGNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKWGIAFAKTFLLGLLHGKILSLKDIMLSLGEPGGAGENGESPPEDEKKEPPPEDGNKELKDNHILNHVGLTDGPRSSIEMDHLNFINNPYLTIHVPIASEESDLEMPTEEETDTFSEPEDIKKPLQPLYDGNSSVCSTADYKPPEEDPEEQAEENPEGELPEECFTEACVKRCPCLYVDISQGRGKMWWTLRRACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFILEMLLKWVAYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDISVVNNKSECESLMYTGQVRWMNVKVNYDNVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPDYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDFVTKQVFDISIMILICLNMVTMMVETDDQSQLKVDILYNINMVFIIVFTGECVLKMFALRHYYFTIGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPTLENPGTNIKGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSEPLCEDDFEMFYETWEKFDPDATQFIDYSRLSDFVDTLQEPLKIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQTMEEKFMAANPSKVSYEPITTTLKRKQEEVCAIKIQRAYRRHLLQRSVKQASYMYRHSQEGNGDGAPEKEGLLANTMNKMYGSEKEDNGVQSQGEKEKDSTEDAGPTTEVTAPSSSDTALTPPPPSPPPPSSPPQGQTVRPGVKESLV
What is the function of this protein?
Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient.  Alternates between resting, activated and inactivated states (PubMed:11834499).  Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K(+) levels (PubMed:18317596, PubMed:21881211).
What are the official names of this protein?
Sodium channel protein type 4 subunit alpha, Sodium channel protein skeletal muscle subunit alpha, Sodium channel protein type IV subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARND_SALPA
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDNMGRHLWRLIKPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLGQIVRGHIPGREGWLGCQQAVSAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: LUXS_ALKCK
Sequence: MPSVESFELDHTIVKAPYVRHCGKHKIGSDGEVNKFDIRFCQPNKEALKPGVIHTLEHLLAINIRRFSEEYDHFDVIDISPMGCQTGYYLIMSGTPSVEEIIDVLEKTMTYSLSIETVPAATEKECGQAALHDLEGTKEVMRKWLSEDKGSLKQVF
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RBL_HUMBA
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GTX3C_NEOGO
Sequence: GWKDWLNKGKEWLKKKGPGIMKAALKAATQ
What is the function of this protein?
Shows a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.  Has also antimicrobial activity against S. cerevisiae.  Has insecticidal and non-hemolytic activity.
What are the official names of this protein?
M-poneritoxin-Ng3c, M-PONTX-Ng3c, Poneratoxin, Ponericin-G3.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_MYCSS
Sequence: MFLGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKSQDHSLAVYPRAEFEKLARRASQASRSNPEARAFLRNLAAATDEQHPDAQGRITLSADHRRYASLSKECVVIGSVDYLEIWDAAAWQEYQQAHEENFSAATDETLRDII
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GRPE1_BUCAP
Sequence: MKNKKEEKINNLKKEEKINNLKKEEKINNLKKEEKEKNDDVQNKIIDLLEIKLKKSQEKIINMQLKNHEEILKLNYRLNSDIEKSRKFSLEKVIIEFLPIIDNIERALSVIKDKKEAFYLEIINKMNFIFSLLEEILSEFNVSKINEKNISFDPEIHQAMSINYNDEIEDNHVVDVMQSGYMLHKARLLRPAMVIVSKRKNN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE 1, HSP-70 cofactor 1.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHP_XYLFT
Sequence: MLEHELTVTNKLGLHARATAKLVQTMSKFQSNTTLSTKGREVNAKSIMGVMLLAASQGTVIRVRIDGEDEHTAMQALSELFENRFNEDT
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I.  Phospho-HPr then transfers it to the PTS EIIA domain.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLE3_CHERA
Sequence: TEFSADQIEDFKEAFGLFDRIGDSQVAFNQVADIMRALGQNPTNKDVTKILGNPSADDMANKRLNFDAFLPMLKEVDALPKGTYDDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMTEPEIDALMAGQEDEGSVHYEAFVKHIMSV
What are the official names of this protein?
Myosin light chain 3, skeletal muscle isoform, LC-3, LC3, Myosin light chain alkali 2, Myosin light chain A2.
Protein: RL17_BORPA
Sequence: MRHGNGLRKLNRTSSHRLAMFRNMAVSLITHEAIKTTLPKAKELRRVIEPLITLGKEPTLANKRLAFARLRDRDAVVKLFAEIGPRYANRNGGYTRVLKMGFRQGDNAPMAFMELVDRPEVDASEADSDAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DNAJ_DESVM
Sequence: MSQRDYYEVLGVARDASEDEIKRQYRKLALQYHPDRNPDNPEAEQMFKEAAEAYDVLRDADKRARYDRFGHAGLNGNGGGHGFANADDVFAHFSDIFGDLFGFATGSSRMRGPRPQAGADLRYNLSISFRQAAKGDEVTLRLPKKVTCDECNGSGAAAGTKPETCRHCGGNGQIRQSQGFFQIAVPCPVCRGEGQVIPTPCPKCKGSGILQQVRELAVRIPAGVDTGNRLRLRGEGEPGLHGGPPGDLYVVVSVEQDKTFRRQGQDLVITHEVSFVQAALGDRIEVPTLDDPVTLDIPKGTQSGEVFRLTDQGLPYLGHHQKGDLLVEVRVLTPVSLTKKQEELLREFAKLEEGKPFEKVKKVARKIGKAMGME
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD2_BRADU
Sequence: MSNAPLANQSLQDFVARHQRLFVLTGAGCSTNSGIPDYRDSHGNWKRTQPVNFQAFMSEEHTRRRYWARSLIGWRRFGQARPNDAHHALARLEANGRCGMLLTQNVDRLHQSAGHRQVIDLHGRLDLVRCMGCGAKTPRSEFQDTLGRANAEWLALDASDAPDGDADLEHADFSSFKVPACEACGGILKPDVVFFGENVPRDVVATAQDHLSQADAMLIVGSSLMVYSGFRFVQAAAQRQIPIAAVNLGRTRADDLLTLKVEERCEAALAFLL
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase 2, Regulatory protein SIR2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPARI_HELPZ
Sequence: MDIIGQVYCFTGAPHTITCLLREQFINWYIKYKRSENYPAFRELVVMYRLFLALGFLTFINAAGQRCRFTDVERDKGYTGMLLKGRLRKTAGNGRTVELICGRGNHNYTCESGVLKESSPRQARCGCKGILEMLFDMPKEERPSPMYDSVTYDPTPNTPTTVGKDGIWNGVDYRNGSTVKPYCDTGPVINGSSKAVCVSGKWVPTLGVCPKMCSIGSLKENGKFVDVTATTKGDELNPPPREQTLIPIVRKVDKDKVQHGVKVVALCKAEDSTTAAEGVQEFECDNGKWKPEPVPCP
What is the function of this protein?
Secreted protein which suppresses the host allergic response by inhibiting the interaction of host IL33 with its receptor in order to maintain parasitic infection (PubMed:29045903).  Binds to both host IL33 and host nuclear DNA and this dual binding blocks the interaction of IL33 with its receptor, and tethers IL33 within necrotic cells, preventing its release, and blocking allergic response initiation (PubMed:29045903).
What are the official names of this protein?
Alarmin release inhibitor, HpARI.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: CHIA1_ASPFU
Sequence: MVSSKLSFVATAVAALAPLASAFDASSRSNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFGYATMANTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLHCDPSPPVTSSSAIPSSTPVTTPSPSSSAVPSSTPAVSETPSPSSSAVPSSTPVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSTSPSTPVIPGTSASSSPVSSSSAVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSVPSSTPAIPGGSSSSSEAVASSTPLVTLTLTVSPTPAPSSSESSSTDLSSSTQTDVGTAPSQPAGPSTTATATTSSSSSSTDESSTTVGSGNGNGSGSTTTTAATDSITAAPTATSSATATGATSEPVTITTIIVTSYIDICPTGFTTVTTTYTTTYCPGTNTATATATVTNPPSGPGGAGSQTTAPTVPEGWTTTVTICTQCAAKPTTVTLTLPVTETGSTSTDAVPAPPAATGEGSNPTQPSGASPTGGNGSFSEEPVPPPAVTQVSTSTEIVTLVRPTSSRPLILGTGTVHPSSTLAVKPSAKPSGQNSGSSSHVPIPPSYTQEAVSPLSTGAASRVTGLGHGLVLTVLTLSAFFVL
What is the function of this protein?
GPI-anchored chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Required to reshape the cell wall at the sites where cell wall remodeling and/or cell wall maturation actively take place such as sites of conidia formation (By similarity).
What are the official names of this protein?
Endochitinase A1, Chitinase A1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall.
Protein: SENX3_MYCS2
Sequence: MSLLTLIAGVAVGVTVVPRIVARRQRRAAYAAGMTVSQMLQHITSLSPMGVAVVDTFNDVVYSNDRAVELNVVRDRILDDRAWQAAQRVFETGQDVEVDLSPLKVANPGRSGISVRGKVRLLTDDDRRFAVVYIDDQSEHARMEATRRDFVANVSHELKTPVGAMSVLAEALLASADDPDTVRRFAEKMVAESHRLADMIGELIELSRLQGAERLPDLDAVDVDSIVSEAVSRHKVAADNSQISITTDAPTGYRVLGDEGLLVTAIANLVSNAIAYSPNGTDVSISRRKRGGNIEIAVTDRGIGIAKDDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPEYPDPESHSDEREDQRER
What is the function of this protein?
Member of the two-component regulatory system SenX3/RegX3 involved in stress response (PubMed:17526710, PubMed:18083811, PubMed:22956756).  The system is involved in phosphate starvation response (PubMed:17526710).  Probably exhibits a dual role as a phosphatase or a phosphodonor for the response regulator RegX3, depending upon phosphate availability (Probable).  When environmental phosphate is abundant, SenX3 is required to maintain RegX3 in an unphosphorylated state, where it is unable to bind target DNA (Probable).  Under conditions of phosphate limitation, SenX3 autophosphorylates and then transfers the phosphate group to RegX3 (Probable).  Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system (PubMed:17526710).
What are the official names of this protein?
Sensor-like histidine kinase SenX3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ACYP_ENTFA
Sequence: MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVRNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SYDND_CYAP4
Sequence: MRTHYCGDVRSHDVGTTVTLFGWVDRRRDHGGVIFLDLRDRSGVVQIVSDPERTPNSYAKAEQLRNEYVVKVTGRVSARPEESLNPRLPTGEVEIYADQIELLNAVRKQLPFQVSTTESESVREDLRLKYRYLDLRRETMAANLQLRHQVVKAMRRYLEDEQNFVEIETPVLTRSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVAGYDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSQEEILELNEALVCHIFKQVKGIELPRPFPRLTYAEAMDRYGSDKPDTRFGLELVNVSDLMKDSGFKVFSGAVASGGLVKVLPIPNGNDLISNVRIKPGGDLFKEATDAGAKGLAYIRVREGGEIDTIGAIKDNLTEAQKAELLQRTGAKPGHLLLFGAGTAAIVNKTLDRLRQVLGRELNLIDPAKINLLWIVEFPMFEWNADEKRLEALHHPFTAPYPEDVQDLKTAQAQAYDLVYNGFEVGGGSLRIYQTELQKQVFETIGLSPEEAQNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEESIRDVIAFPKTQQARCLLTSAPAEVDLRQLKELHVASTSQPKVNG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_BORGP
Sequence: MEKKETKNDAEKNNKQDNKSTKSQKKENLNLVNSDKKITELENEISNLKDLYLRKQAEFENFRKRLEKEKDNFVKFANETIMKDVVNFLDNLERAINSSRKSKDFDNLLTGISMIENEILSIFDKKYNLKKFGENGENFDPSRHEAISIEEKEDLKNPEIVEVYQKGYCYNDRILRTAKVKVAQSKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD1_PLAF7
Sequence: MNENLENFSTIDLLNELKRRYACLSKPDGRYIFLGAPGSGKGTQSLNLKKSHCYCHLSTGDLLREAAEKKTELGLKIKNIINEGKLVDDQMVLSLVDEKLKTPQCKKGFILDGYPRNVKQAEDLNKLLQKNQTKLDGVFYFNVPDEVLVNRISGRLIHKPSGRIYHKIFNPPKVPFRDDVTNEPLIQREDDNEDVLKKRLTVFKSETSPLISYYKNKNLLINLDATQPANDLEKKISQHIDG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (PubMed:15478799).  Has very low activity with CTP, GTP, ITP and UTP and no activity with GMP, CMP, UMP or IMP in vitro (PubMed:15478799).
What are the official names of this protein?
Adenylate kinase 1, PfAK1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAHC_ECOLI
Sequence: MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCSFYAAGGGKSGFIRSLAVNYSGMVWAFFAALTAGWLASVSGLSAFWASVITTVPFSAVVVWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGVISEYGGQKLSEATTKRDGY
What are the official names of this protein?
Uncharacterized protein YahC.
What is the protein family that this protein belongs to?
To E.coli YcdZ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHYDA_ECOL6
Sequence: MRVLIKNGIVVNADGQAKQDLLIESGIVRQLGTDISPQLPCEEIDASGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: CTXN2_MOUSE
Sequence: MSSTYCGNSSAKMSVHEVSESSLSLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA
What are the official names of this protein?
Cortexin-2.
What is the protein family that this protein belongs to?
Belongs to the cortexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPEH2_HALH5
Sequence: MDTMGRHVIAELWGCDVDKLNDLSFIEQVFVDAALKAGAEVREVAFHKFAPQGISGVVIISESHLTIHSFPEHGYASIDVYTCGDRIDPNVASNYIAEALKATATEVVELPRGMGPIQLEKPKVKVL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 2, AdoMetDC 2, SAMDC 2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: Y2019_YERPS
Sequence: MYPVDLHMHTVASTHAYSTLHDYIAEAKLKNIKLFAITDHGPDMADAPHYWHFMNMRVWPRLVDGVGILRGIEANIKNLDGDIDCTGPMLDAVDLLIAGFHEPVFPPQDKAANTQAMIATMAQGNVHIISHPGNPKYPVDIPAIAQAAAKYNVALELNNSSFAHSRKGSEANCRAIAAAVRDAGGWLALGSDSHIAYALGIFEHCERIIAEVNFPQERILNVSPRRLLDYLEQRGRPAIPELAEL
What are the official names of this protein?
Probable phosphatase YPTB2019.
What is the protein family that this protein belongs to?
Belongs to the PHP family.