PharMolix/UniProtQA huggingface dataset:
Protein: MURD_BUCBP
Sequence: MTRNYLHKKILIFGMGLTGISCLNFFLSKGIYPKIMDTDKRPKHIEKIIKFKNICYHTGSVNYSWILQSNLIIVSPGITPSHPALKFATKKNIEIIGDIELFVQETKVPIIAITGSNGKSSVTKIVKEIIQKAGFTTYIGGNIGIPALNIVNKFAHFFILELSSFQLERTFSLKAYIATILNITPDHLNRYSSDIKEYEKAKQKIYKNSKICIINVDNPVTINRQAQLTKCISFGVHSGDYHLSHTYTNTWLCYKSLKLINTKKLKLSGRHNYINMLSALAIVHELKISFKISVRILKNFLGLPHRCQKVYKNNNITWINDSKSTNIASTKSAIQSINTKGKIRLILGGDKKSSNLNLLKPILKNNAIVIYCYGKDKKELFNLYPHKSKIFETLQEVMQHISVQVQPGDVVLLSPACSSLDQFSGFEERGNTFVKLIQELIH
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_CLOB1
Sequence: MAKVKITLVKSLIGRKKDQIATVNALGLKKIGNIVEHEETPQISGMIKKVSYLLKVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: AAXC_CHLTA
Sequence: MLLKKRSPTSILGTLALTGIVISSMIGGGIFSLPQNMVASASAGAVMLAWMLSGIGIFFIANTFKTLSIIRPDLKAGIYTYSREGFGPYVGFTIAWGYWLCQIFGNVDYAVITMDALNYFFPPYFAGGNTIPAILLGSLLIWIFNYIVLRGIRQASFVNIIGAVCTLIPLLLFILITARFFKFSIFKTDFWGTAPQHTLGSIGSQLKSTMLVTLWAFIGIEGAVVISGRAANLSSVGKATILGFSGCLLIYVLLSLLPFGSLFQYQLAKIADPSTAGVLNILVGKWGEVLMNTGLLIAVLTSWLSWTILASEIPYAAAKNGTFPECFAIENSKHAPSFSLFMTSGLMQITMLLVYFSSNAWNTMLEITGVMVLPAYLTSSLFLVKFSLSKKYPKQAAIKARIAMITSLLGSLYSLWLIYAGGLQHLFMVAILLALGIPFYVDSGIRHKQEKTFLNRKEILKMTIVALAALLAIFLFSANKIHL
What is the function of this protein?
Catalyzes the exchange of L-arginine for agmatine.  The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).
What are the official names of this protein?
Arginine/agmatine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFP_METS4
Sequence: MKVIASSLRKGNVVEKDGRLYVILSAENIHPGKGTPVTQLDMRRITDGVKVSERYRTTEQVERAFVEDREHTFLYKDGEGSHFMNPESYEQVAVPDDVIGDQAAYLQEGMAVMLSLHNGVPLAIELPQRVTLEIVETEPVTKGQTASSSYKPAVLSNGVRTLVPPHITTGTRVVIMTADGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAXB_CHLFF
Sequence: MTYGTRYPTLAFHTGGIGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNIVPVDQCVKSFKHGAVLEVIMAGRGAATVDGTHAIATGVGICWGQDKNGELIGGWAAEYVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSIVKHSEFQYFHNYINIKKKYGFSLTALGFLNFENADPVTIK
What is the function of this protein?
Part of the AaxABC system, catalyzes the decarboxylation of L-arginine.  The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase AaxB, PvlArgDC, Biodegradative arginine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the pyruvoyl-dependent arginine decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMGN_BOVIN
Sequence: MDLGKDQSLSKLHQTPDHHQEESHVPEVIGTWSLRNREQLRKRKAEAQEKQTSQWQYREKKHKRQRTGKRSERGRKRQQNTEMKVELPSQLEKEMMEKAPAPGEKEIEPPGSVTEVLLPAVSPQRVAPAKHLSEVGQESVTLQENSSEYQATAVQNQPSEICQDMAESEDLSPKMCQEIAIFQDQPFKMFRNMAQPEDVSPKTCQEDIAAKVLSSKTSEDTTDLEECSLEAHPKPDMPKASTLETYQKRPEPEEPDSETGQGIVETESFVSNTQQEMAVPKELATEIHQETVEPEHFSHKIYREIAMSKDPSHKTTQETSVPDKYPPEMYQETPGSEEYSLEIYQETTGPEAYAPEIYQETPGPEDLSTKTYKDKDVPKECFPKLYQEIGGPQDQDSKAHQEDAKDVYTFPQEMKENPKAEEPEIIEIPNVPQESNPENDIYSYVLF
What is the function of this protein?
Regulates the proliferation and differentiation of hematopoietic cells.  Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model.  May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) (By similarity).
What are the official names of this protein?
Hemogen, Hemopoietic gene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PC_CLOD6
Sequence: MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILNLPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPEQKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHEHVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDIIVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLLPLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRPEFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVSSFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKALMDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKETHKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILVIDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHKAKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: HIS6_BUCAI
Sequence: MLAKRIIACLDVDDGVVVKGIKFQNHKIVGDIVPLARRYAKEGIDELVFYDITAATKNKLVDRSWIKNVSKVINIPFCVAGGIKSVEDAKKVLSSGADKISINSSALIDPNLITKISERFGVQCVVIGIDSWFDKTKNSYMVQQYTGDISKTYQTSWKTSDWVKKVQEKGAGEIVLNMMNKDGLQKGYDISHLSEIRKICKVPLIASGGAGSVEHFYEALYYSNVDGVLAASVFHKNIVEIKVLKKKLIARGMEIREC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_CITK8
Sequence: MSMSTSTEIIAHHWAFAIFLIIAIGLCCLMLVGGWFLGGRARARSKNTPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SHUT_HHV2H
Sequence: MGLFGMMKFAQTHHLVKRRGLRAPEGYFTPIAVDLWNVMYTLVVKYQRRYPSYDREAITLHCLCSMLRVFTQKSLFPIFVTDRGVECTEPVVFGAKAILARTTAQCRTDEEASDVDASPPPSPITDSRPSFAFSNMRRRGHAFAPGDRGTRAAGPGPAAPSGAPSKPALRLAHLFCIRVLRALGYAYINSGQLEADDACANLYHTNTVAYVHTTDTDLLLMGCDIVLDISTGYIPTIHCRDLLQYFKMSYPQFLALFVRCHTDLHPNNTYASVEDVLRECHWTAPSRSQARRAARRERANSRSLESMPTLTAAPVGLETRISWTEILAQQIAGEDDYEEDPPLQPPDVAGGPRDGARSSSSEILTPPELVQVPNAQRVAEHRGYVAGRRRHVIHDAPEALDWLPDPMTIAELVEHRYVKYVISLISPKERGPWTLLKRLPIYQDLRDEDLARSIVTRHITAPDIADRFLAQLWAHAPPPAFYKDVLAKFWDE
What is the function of this protein?
Minor structural protein that acts as an endoribonuclease during lytic infection.  Degrades host mRNAs in the cytoplasm by cutting them at preferred sites, including some in regions of translation initiation.  Together with inhibition of host splicing by ICP27, contributes to an overall decrease in host protein synthesis.  Also, after the onset of viral transcription, accelerates the turnover of viral mRNA, thereby facilitating the sequential expression of different classes of viral genes.  Binds translation initiation factors eIF4H, eIF4AI, and eIF4AII, thereby may interact directly with the translation initiation complex and thus digest specifically mRNAs.  Also impedes antigen presentation by major histocompatibility complex class I and class II molecules, inhibits secretion of cytokines that would otherwise recruit lymphocytes and neutrophils cells to the site of infection and blocks the activation of dendritic cells.  Impedes the alpha/beta interferon-mediated response to infection (By similarity).
What are the official names of this protein?
Virion host shutoff protein, Vhs.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae VHS protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NTPPA_MARMM
Sequence: MTLADPALPRPRLILASASPRRFDLLSGAGLSPDAVEPTHIDEHEIPGELPGPLALRLAQEKAMAHPGSDDAFILAADTVVGVGRRILPKTETEAEARRCLDLLSGRNHRVFTGIAARGPDNRFAARVVETRVKFKRLSQPEIDAYIASGEWRGKAGGYAIQGRAGCFVINLIGSFTGVVGLPLYETANLLTGLGYPVTARMGEGGSA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_SHIB3
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAANHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELVSGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEIRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ4_YEAS1
Sequence: MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLADAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAISGWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMDKLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYISKRYRQCHDFYHAITNMPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSCKPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTPA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TRUB_META3
Sequence: MELITKEESKTNYEYGCDPYNRPIGELLKNGIVVIDKPSGPTSHEVSAWVRDILKLKLAGHGGTLDPKVTGVLPVALENTSKCISVWHMIPKEYVCLMHLHRDTEEEELLKIFKKFTGRIFQRPPLKAAVKRSLRIRKIYELELLEKDGRDVLFRVRCQSGTYIRTLAEDMGEALGTSAHMQELRRIVSGPFTEKDIVYLQDLTDAYIFWKENGDETELRKIIKPMEYGLQHINKIIVKDSAVDAICHGANVYLNGVSKLSKGIGADETVLIETLKGEAIGIGTALLNTKNVLKESKNEEDNREKYKEPIVDIERIFMSPNTYPKMWKKKK
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: EFP_NOSS1
Sequence: MISSNDFRPGVSIVLDGSVWRVIDFLHVKPGKGSAFVRTTLKNVQSGKVLEKTFRAGETVPQATLEKITMQHTYKEGDEFVFMDMESYEEGRLSAAQIGDRVKYLKEGMEVNVIRWGEQVLEVELANSVVLEVIQTDPGVKGDTATGGTKPAIVETGATVMVPLFISQGERIKIDTRDDKYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS2C_ARATH
Sequence: MARKSIRGKEVVMVSDDDDDDDDDVDDDKNIIKCVKPLTVYKNLETPTDSDDNDDDDDDDVDVDENIIKYIKPVAVYKKLETRSKNNPYFLRRSLKYIIQAKKKKKSNSGGKIRFNYRDVSNKMTLKAEVVENFSCPFCLIPCGGHEGLQLHLKSSHDAFKFEFYRAEKDHGPEVDVSVKSDTIKFGVLKDDVGNPQLSPLTFCSKNRNQRRQRDDSNNVKKLNVLLMELDLDDLPRGTENDSTHVNDDNVSSPPRAHSSEKISDILTTTQLAIAESSEPKVPHVNDGNVSSPPRAHSSAEKNESTHVNDDDDVSSPPRAHSLEKNESTHVNEDNISSPPKAHSSKKNESTHMNDEDVSFPPRTRSSKETSDILTTTQPAIVEPSEPKVRRVSRRKQLYAKRYKARETQPAIAESSEPKVLHVNDENVSSPPEAHSLEKASDILTTTQPAIAESSEPKVPHVNDENVSSTPRAHSSKKNKSTRKNVDNVPSPPKTRSSKKTSDILTTTQPTIAESSEPKVRHVNDDNVSSTPRAHSSKKNKSTRKNDDNIPSPPKTRSSKKTSNILATTQPAKAEPSEPKVTRVSRRKELHAERCEAKRLERLKGRQFYHSQTMQPITFEQVMSNEDSENETDDYALDISERLRLERLVGVSKEEKRYMYLWNIFVRKQRVIADGHVPWACEEFAKLHKEEMKNSSSFDWWWRMFRIKLWNNGLICAKTFHKCTTILLSNSDEAGQFTSGSAANANNQQSMEVDE
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.  Required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization.  Regulates the anteroposterior organization of the endosperm.
What are the official names of this protein?
Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2.
What is the protein family that this protein belongs to?
Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSRB_YERP3
Sequence: MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKDQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYGDLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NFUA_SALAR
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYVLQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: PG072_MONPV
Sequence: MNPKHWGRAVWTIIFIVLSQAGLDGNIEACKRKLYTIVSTLPCPACRRHATIAIEDNNVMSSDDLNYIYYFFIRLFNNLAFDPKYAIDVSKVKPL
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves thiol-disulfide transfer between OPG072, OPG128 and OPG088.
What are the official names of this protein?
Probable FAD-linked sulfhydryl oxidase OPG072, Sulfhydryl oxidase.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG072 family.
Protein: FOLD_SHISS
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: NIA_BETPN
Sequence: MAASVENRRFTHHEPAVNGLVRTFKPVPNSHRSDSPDLGRQIPSSPKKQVATGEDSSSEDENENDYKELIQKGNGELEPSILDPRDEATADNWVERNATMVRLTGKHPFNSEAPLTRLMHHGFITPAPLHYVRNHGPVPKARWEDWSVEVCGLVKRPARFTMDRLVTEFRSREFPVTLVCAGNRRKEQNMVKKTIGFNWGAAGVSTSVWRGVPLRDVLKRCGIFSRGRGAFNVCFEGAEDLPGGGGSKYGTSVKYEMAMDPARDIILGYMQNGERLSPDHGFPVRMIIPGFIGGRMVKWLKRIIVTTKESDNYYHYNDNRVLPSHVDADVAKAEAWWYKPEHIINELNINSVITTPCHEEILPINSWTTQRPYTLRGYAYSGGGRKVTRVEITMNGGEKWRVCALDHPEKPNKYGKYWCWCFWSLEVEVLDLLGAKEIAVRAWDEAHNTQPEKLIWNVMGMMNNCWFRVKTNVCKAHMGEIGIAFEHPTVPGNESGGWMAREKNLETSSDANQSLKKSVSSPFMNTSSKMFSMSEVKKHNSAESAWIIVHGHIYDCTHFLKDHPGGADSILINAGTDCTEEFDAIHSDKAKKMLEDYRIGELITTGYVSDSPNSTVHGASNTSHLAPIKEIAPLRNVALIPGAKIPTKLVYKKSLSHDVRLFRLALPSDDQVLGLPVGKHVFLCATIDDKLCMRAYTPTSTIDEVGYLDLVVKIYFKNSNPRFPNGGLMSQHLDSLPIGSVLHVKGPLGHVEYTGRGNFLVHGEPKFAKRLAMVAGGTGITPIYQVIQAILKDPEDETEMFVVYANRTEDDILLREELDDWAKKHEKLKVWYVVKESKREGWEYSVGYIRESILREHIPEGSDDVLALACGAPSMIEEAVRLNLEKMNYDTKNSLIIF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NAD(P)H], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: ACDH_MYCBP
Sequence: MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLNEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the conversion of propanal to propanoyl-CoA, using NAD(+) and coenzyme A.
What are the official names of this protein?
Propanal dehydrogenase (CoA-propanoylating), Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y271_MYCPN
Sequence: MRKKKFLSRFSFSSLFLLCGTLLSACTGIQADLRNLIKETTGKDIDLSKAIKTKEGKKNIIASLKKSYEVNPKDTTKLLLDAWKQSFEEGKLGIADFDFDHVAYPQTNDPFTMERKVDHFQMTYQSFKDLLVEARLSYTFNWFGDYSSGDFTAKRGDKHYFYLFLKIKSDPKKQFSAKKFLTEGEAFTDQEGKQTTRNLEWIEFSASISWWTKGKDDVSQKSLKKFLESFATNTGYSSDINLFSYLEYLIK
What are the official names of this protein?
Uncharacterized lipoprotein MPN_271.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RPIA_CANGA
Sequence: MSYTPLPNINDFPTLGNPLEDAKRAAAYRAVDENLNFDEHRIIGVGSGSTVVYVAERIGQYLKDEKYHDKVSKFICIPTGYQSRNLIQDNGLILGSIEQHPHVDIAFDGADEVDHNLQLIKGGGACLFQEKLVSTSAKIFIVVADSRKKSDTNLGINWKRGVPIEIVPSAWSRVQHDLTSILHANSAPVRQGGSAKAGPVVTDNMNFLIDADFGEIQDPKALHEQIKMLVGVVETGLFIDNAHRAYFGKPDGSVEVIDKK
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAF13_MOUSE
Sequence: MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 13, Transcription initiation factor TFIID 18 kDa subunit, TAF(II)18, TAFII-18, TAFII18.
What is the protein family that this protein belongs to?
Belongs to the TAF13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FDHD_STAHJ
Sequence: MNKDVLQGQSIIRYEEGQLIQTTDSYVTEFPLTINVNGTEFATVICSPTHMEELVVGFLASEGAIYKKEEIKSLQIDDSKGFAHVELTKDLGDRFEYSTKRMIASCCGKSREFYFHNDAAIAKTSMSKITLTPKQVLNMMTGLQTASTLFKQTGGLHNAAISDGDEFFEHRQDIGRHNALDKLYGFCLERRIPVRNKVLIFSGRISSEILLKAAKIGVGVILSKSAPTTLAITLANDLNITAIGFIRDGSFNIYSHPERIKATE
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN32A_DROME
Sequence: MEKRIELERRARKVNQITELNLDNCRSTSIVGLTDEYTALESLSLINVGLTTLKGFPKLPNLKKLELSDNRISSGLNYLTTSPKLQYLNLSGNKIKDLETLKPLEEFKNLVVLDLFNNDATQVDNYREKIFKMLPSLNFLDGFDCNDEEVQSDGDDDDEVNGNDSDEVGVSDEDDDSDDSDEEANGEVSLSEVYNDDLEEDNSDWEGEDEAGEEDEEEDSDIDDADGDANESAASVNAKDKDGEKEADESQVRGKKRKHDG
What is the function of this protein?
Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex.
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member A.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.