PharMolix/UniProtQA huggingface dataset:
Protein: PANB_CERS5
Sequence: MSVNSPVRPVMAADILARKGGEPLVCLTAYTTPMARLVDAHCDITLVGDSLGMVVHGLPTTLGVTMEMMILHGKAVARGTSRAMLVIDMPFGSYEESPAQAFANARRLMAETGCAAVKLEGGRHMAGTIRFLVERGIPVMAHVGLTPQAVNALGGYKVQGRGADADRVMEDAIAVAEAGAFSVVLEKVPDGLSQRITQRVAIPTIGIGASAHCDGQVLVLDDMLGLFTDFRPKFVKRYGELGTAADEAIAAYAAEVRARRFPASEHVFPDELKGKQP
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_CUTAK
Sequence: MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHTSAGRIPTDKGYRLFVDRIATLKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQVAIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQIVELPGHDEQSLAALRTRLNETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAFGAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYGPEDALSSLGVVGPIRMDYPSTMAAVRAVARYVGRFLAEG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: HIS2_LEPBP
Sequence: MEFLLKLEDLLRKRKEELPEKSYTAELFRDGVDRILKKIGEEAGEVIIAAKNPNEKELIHEIADLIFHLEVLMVEKGISLTTIAKELEKRHS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_HAEI8
Sequence: MAETHSLGTKILIKIIRLYQIMISPFIGARCRFVPTCSCYGIEALKTHGLLKGGWLTLKRVLKCHPLNAGGFDPVPPKTNNNDEKK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DER_CLOBJ
Sequence: MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDESDGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKVKEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ATPA_TRIL1
Sequence: MELRAEEISEIIKKQINEYGKEVEVSETGTIISIGDGIARIHGLAGAMAGELLEFPGGVSGMVLNLEEDNVGAAILGEFAEIKEGDTVKRTGRITEVPVGDALVGRVVNAIGQPIDGKGPINSSTFSKVEIKAPGIVARKSVHQPMATGLKAIDSMVPIGRGQRELIIGDRQTGKTAVAVDTIINQKGGDVICIYVAIGQKRSTVAQVVSKLTEHGAMDYTIVVAATASESAPLQFIAPYTGVTMGEYFRDNKKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERACKLSDECGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVGLSVSRVGGSAQTKSMKQVAGTLRLNLAQYREMAAFAQFGSDLDKATQMQLARGERLVEILKQPQYRPIPNEKQVLVIFAANNGYLDDYPVSALKKYETELYAFFDNRQADVLTELREKQAIGDDLKAKLVSALDQFKKEFTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NSP5_ROTAD
Sequence: MSLSIDVTSLPSISSSIFKNESSSTTSTLSGKSIGRNEQYVSSDIEAFNKYMLSKSLEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSTQSRPSSNVGCDQMDFSLTKGINVSASLDSCVSISTNHKKEKSKKDKSRKHYPRIEADSDSEDYVLDDSDSDDGKCKNCKYKKKYFALRMRMKQVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: CP121_ARATH
Sequence: MTTIAAAGLNVATPRVVVRPVARVLGPVRLNYPWKFGSMKRMVVVKATSEGEISEKVEKSIQEAKETCADDPVSGECVAAWDEVEELSAAASHARDKKKAGGSDPLEEYCNDNPETDECRTYDN
What is the function of this protein?
Acts as a linker essential in the assembly of a core complex of PRK/GAPDH.  Coordinates the reversible inactivation of chloroplast enzymes GAPDH and PRK during darkness in photosynthetic tissues.
What are the official names of this protein?
Calvin cycle protein CP12-1, chloroplastic, CP12 domain-containing protein 1, Chloroplast protein 12-1.
What is the protein family that this protein belongs to?
Belongs to the CP12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYN_STRPB
Sequence: MSKKLISIVDVKDYVGQEVTIGAWVTNKSGKGKIAFVQLRDGSAFFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITDLEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGFIKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVEALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDELGMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_BACFR
Sequence: MSQPFFQFKQFTVWHDKCAMKVGTDGVLLGAWTPVESSARILDIGTGTGLVALMLAQRCSASVIALEIDGKAAQQAAENITRSPWGSRIEVVCQDFRLYSNKNNSLKYDTIVSNPPYFTDSLKCPDSQRNTARHNDNLSYEELLKGVSNLLSPNGTFTVVIPMDASDSFKDIASSQGLYPSRQLLVITKPGAPPKRTLISFTFIKQDCKEEKLLTEVARHRYSDEYIKLTREFYLKM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FN3KR_ARATH
Sequence: MAVASLSICFSARPHLLLRNFSPRPKFVAMAAMSEDPIREWILTEGKATQITKIGSVGGGCINLASHYQTDAGSFFVKTNRSIGPAMFEGEALGLEAMYETRTIRVPNPHKAGELPTGGSYIIMEFIDFGGSRGNQAELGRKLAEMHKAGKTSKGFGFEVDNTIGSTPQINTWSSDWIEFYGEKRLGYQLKLARDQYGDSAIYQKGHTLIQNMAPLFENVVIEPCLLHGDLWSGNIAYDKNNEPVILDPACYYGHNEADFGMSWCAGFGESFYNAYFKVMPKQAGYEKRRDLYLLYHYLNHYNLFGSGYRSSAMSIIDDYLRMLKA
What is the function of this protein?
Initiates a process leading to the deglycation of proteins (PubMed:15705060).  Phosphorylates low-molecular-mass and protein-bound erythrulosamines and ribulosamines, but not fructosamines or psicosamines, on the third carbon of the sugar moiety (PubMed:15705060).  Protein-bound erythrulosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions (PubMed:15705060).
What are the official names of this protein?
Protein-ribulosamine 3-kinase, chloroplastic, Fructosamine 3-kinase-related protein, AtFN3K-RP.
What is the protein family that this protein belongs to?
Belongs to the fructosamine kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DER_AGRVS
Sequence: MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGEAKLVDLRFHIVDTAGLEEAGADTLEGRMRAQTEIAIDEADLSLFVVDAKMGLTHVDKALADMLRKRGKPVVLVANKSEARGSDGGFYDAFTLGLGEPVPISAEHGQGMIDLRDAIVEAIGVDRAFPEDDDDVAETDIVLRPTVEGEDDEEDLAYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSISVEWDWRGRTIKMFDTAGMRRKARVIEKLEKLSVADTLRAIRFAETVVIVFDATIPFEKQDIQIVDLVLREGRAAVLAFNKWDLVEDPQAVLAELREKTERLLPQARGIRAVPMAGQTGYGLEKLMQSIIDTDMVWNKRISTAKLNRWLDSVQTQHPPPAVSGRRLKLKYMTQVKARPPAFMISCTRPDSVPESYIRYLTNGLRADFNMPGVPIRIHLKASENPFENKRKRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: YB1_MDBVW
Sequence: MLDPTFFIELLTVLRNLHAVSANSYTLVNNLRQIIIDNTATLKDLKQLIVNSRSPNSDIPTTSQSTNIIVEVEEISEKNNSNQKQRDEECNDHSDNETDEVPKKKRSQKRKFVLPPEYDENDSRWTLKHRQMAPGLVELMPHTNVYINAIKLSNCKRLSKDCKSLARLLLVEIFTKSALTICSLTGSRARAYDVEGATIRPGLDETARTVLLTYVEEYGREKGWITLDTQSIQNSIRNKMQEFRFKYG
What are the official names of this protein?
Putative BEN domain-containing protein B1.
Protein: NU1C_TOBAC
Sequence: MIIDTTEIETINSFSKLESLKEVYGIIWMLFPILTLVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLLKENLIPSTGDTRLFSIGPSIAVISIFLSYSVIPFGDHLVLADLSIGVFFWIAISSIAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLALCVLSISLRVIRLSNSLSTVDIVEAQSKYGFWGWNLWRQPIGFIVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYIASYLNLLVSSLFVTVLYLGGWNLSIPYIFVPELFGINKRGKVFGTLIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FER_ATRBE
Sequence: ATYKVKLVTPDGPVEFDCPDDVYILDQAEEEGHELPYSCRAGSCSSCAGKVSAGTVDQSDGNFLDDDQMADGFVLTCVAYPQSDVTIETHKEEELTG
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1416_METJA
Sequence: MMDLEGYVRRCLRKKIPENKIIEDGFKRILEIKEDVDEEFAKKFIKAILEEVKTTEKFREIDDENLKTLLKYPKSGVTMGRMGVGSRGEGDFFVHREIARIVKSTKVKAYVSAEEQDDAGIVRADAKYIVAAIDGTHSRLSDFPFLGGFHVTRAALRDIYVMGAEAVALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVGGDMVIGDRLVSAVGAIGVIKEGEPTARRNAEVGDVILMTEGSGGGTITTTALYYGWFDVIYETLNVDFIKACQNLIRSGLIKKIHAMTDVTNGGLRGDAYEISKTAKVSLIFDKEKVYKTINPKVLEMLEVLNIDPLGVSTDSLMIICPEEYADDIKKVTGAIEVGYVEEGEESYLVDGNKKIPLKPMFRESAYTPVKKVVGERKPGDFEEMKEKVRRACDEAIKKKDFVVELLKERKKKF
What are the official names of this protein?
Uncharacterized protein MJ1416.
What is the protein family that this protein belongs to?
Belongs to the HypE family.
Protein: RF3_CHRVO
Sequence: MSADLARIAEEVSHRRTFAIISHPDAGKTTLTEKLLLFSGAIQMAGTVKGKKGGKFATSDWMEIEKQRGISVASSVMQFDYRDHTVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTIKLLNVCRLRNTPIVTFMNKCDREVRDSLELLDEVENVLKIRCAPITWPIGMGKTFRGVYSLLSDAVILFEAGTEKLVSDIEVIQGIDNPRLDELFPLEMEQLRMEIELVKGASNEWSLEEFLAGELTPVFFGSAINNFGVREILNALIDWAPAPQERDATVRNVDPKEAKFSGFVFKIQANMDPKHRDRIAFLRVCSGQFERGMKMKHLRLNRDIAASSVVTFMSHDREIVEEAFAGDIIGIPNHGNIQIGDSFSEGEDLAFTGIPFFAPELFRSVRIKNPLKLKQLQKGLQQLGEEGAVQVFKPHSGGDLILGAVGVLQFEVVASRLAAEYGVDAIFESASIWSARWFSCDDRKKLDEFVKTLQMNIATDAGGNLAYLAPNRVNLQLTQERWPDIVFHETREHAVKLND
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_LACDA
Sequence: MSIVQLDHVSVTFKRKKAADVQAVQDVTLHIEKGDIYGIVGFSGAGKSTLVRTINLLQKPTAGDVVVGGVDFVKDGKQVISGKDLQARRRKIGMIFQQFNLLNETTVIENIAFALKHSDLSDDELEEKCHKLLKLVDLEDKANAYPAQLSGGQQQRVAIARALANDPEILLSDEATSALDPQTTIQILDLLKKLNRELGLTIVLITHEMAAVKKIANKVAVMENGRVVENGNLRDVFLAPKAELTQKFVGGSLAVVDTLKSLNISLAENEALYQLVYSLNNVAKSIIIELYREVGVEASMLYGNVEVLADEPVGTLLVMVKGDADKQKATLKFLSDEGVTVTELDERGNRL
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MID2_SCHPO
Sequence: MLMTASQQDQHAKMYLADIHRALRIPSPIPSTDYECSDYASTIASISRESTMRNFNRSNISSTAPSFAESEDAEDGDSFPYDQTLSNSSSFDDHQSLLPFSTEVRRTPTYSVMNETDSSSTSVEDVNKENILSLNDSCLIKLSDDEASNKSSRSSTPRNSIKSNSSNQGHGDIPIPKKNPARSVCNSKLFNEDTLPAEFEEVSISPPVKLELPTHSHNSSDTSFTNSIVSSVSDMVGLGEGINSIASFGFSEDSSSFQDIKTPPRLSFADENRENCRTDIYRSDSIHEYEEPLTSSITSLDSPHVLDENAPIPLLPKVVSLPDPRFTNVLSAFDALTRTYLLRQNSKVVHATSQKQEMQTSRRVVNSCYMPESLSRNLSSSLQQTGGSGRLFVRLMEIRNLTIPLASGMTTRFTYTISGKHIQVPWNALHSTTKIENEYTFDESISSSIVCTLRAAYDPPKVRTRSTLGKVFSTNKRKSMTTDPVSEALHGFVSEDGTFGEVTINTDSVSRTALGRCQSMVLPIMNKWTVDPAAKDVKPLPRKVGELEIHVFFLPALPVSLKELPASIESAMYDLKLAEWDRTLLCDGYLCQQGGDCPYWRRRYFQLIGSKLVAFQQFSKVRRATIDLSEATHIVDDNHYSDEEELEGYLYFESGFRIIFSNGDYIDFYAETVGEKDEWMSTLRQHLGQCSMVHKNWTKSFLSLSF
What is the function of this protein?
Responsible for the proper stability and function of septins during cytokinesis.  Required for the correct formation of the medial septin ring structure in mitosis and for the proper localization of endo-glucanases agn1 and eng1, which are needed for efficient cell separation.  May act as a landmark for the localization of hydrolytic proteins to the medial region.
What are the official names of this protein?
Septin ring organizing protein mid2.
What is the protein family that this protein belongs to?
Belongs to the BUD4 family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Localizes to the medial ring at the cell cortex of dividing cells (PubMed:12654901). Initially forms a single ring, which subsequently splits into two distinct rings as the septum forms, and disappears as cells separate (PubMed:12654901). Requires septins for proper localization (PubMed:12654901).
Protein: FIMI_SALTY
Sequence: MIRKGAALAGLVLMSPVIAQPVMVESGRVHLRGQLVNGGCAVATESQNLRVLMGQYRTNAFTGPGSFAPVSVPFSLRLISCSAEVWRHVGIAFAGVTPAEDPHVFLASGEGIGNAGIGLALFDDQQRQIIPNTLPLHYTPILTSEMTLHFTARYRAISENMTPGRIHSEVWFTLVYP
What are the official names of this protein?
Fimbrin-like protein FimI.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: RL10_DESDA
Sequence: MKRSEKAAVIEAIKAKADKASFAVLTDFKGMTVEELTNLRGSLRKAGGEYLVVKNTLARIALTDGTHDVIKDKFRENIGVAFGFDDPVAVAKALSDFAKQSKLFELRCASLDGKALEVAQIDALAKLPGREQLLGHLLGTMNAVPTNFVSLFANVLRGLLYALKGIEEQKSNAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ATC1_DICDI
Sequence: MTGSHEMESIMLDSMEEEFPVSVETLGKLVDVPKGFDTYAELGGLSGLSTKLKSNIKTGLPLEKSSTEENRVLKYSKNILPDPPHQPLWSIVLDALSDHILILLIVAAVVSIVLGSIDYTSDHPETGWIDGVAILVAVILVVGITSLNDFKNQARFRELNDKSNDKEVKGIRGGEQCQISIFDVKVGDIISLDTGDIICADGVFIEGHALKCDESSITGESDPIKKGQPQDNMDPFLISGSMVIEGFGTMLVTAVGVNSFNGKTMMGLRVASEDTPLQMKLSVLASRIGYFGMGAAILMLLIAIPKYFIQRKVHDIEITREDAQPIVQLVISAITIVVVAVPEGLPLAVTMALAYGMMKMFKENNLVRNLASCETMGSATTICSDKTGTLTQNVMSVVTGTICGVFPTLDGIAQKIPKHVQSILTDGMAINSNAYEGVSSKGKLEFIGSKTECALLNFGKLFGCDYNEVRKRLEVVELYPFSSARKRMSVLVKHDQNLRLFTKGASEIILGQCGSYLDEAGNIRPISEAKAYFEEQINNFASDALRTIGLAYRDFQYGECDFKEPPENNLVFIGIVGIKDPLRPEVPEAVEICKRAGIVVRMVTGDNLVTAQNIARNCGILTEGGLCMEGPKFRELSQSEMDAILPKLQVLARSSPTDKQLLVGRLKDLGEVVAVTGDGTNDGPALKLANVGFSMGISGTEVAIAASDVVLLDDNFASIVRAVLWGRNIYDAICKFLQFQLTVNVVAVTVAFIGTLTSDVVEDKDNSSSSGSADKVTEEEPRQGSPLTAVQLLWVNLIMDTLAALALATEPPTPELLERPPNGKNAPLITRSMWKNIIGQAALQLAILFTILYQGHNIFQHFVPQAHGPIIKNGLHHYTLVFNCFVFLQLFNEINARVLGSRTNPFKNFFNNPIFIAVMIFTLGVQIIFVTFGGSATSTDSLYIVEWICCVVVGAISLPVGLLLRKIPIREPVVKNEIPVHSEAVYTSPSPNPSSSNLLGSGGAKPISKDYPTSGESTPPINDEGSPLVTRKTSVGASANDNINTPIPSSSSNLVNLNKPTQVGRGWQIVRQTHKKLVVINALKEFSQNKEPGLVDVVRGTNRGSLHLPVNQINN
What is the function of this protein?
Calcium ATPase involved in Ca(2+) homeostasis as a component of the contractile vacuole complex.
What are the official names of this protein?
Calcium-transporting ATPase PAT1, PAT1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Contractile vacuole membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Contractile vacuole complex. Localizes to the contractile vacuole membrane in unstimulated cells (PubMed:9885293). Localizes to the cell membrane and the contractile vacuole membrane in cells stimulated by calcium (PubMed:9885293).
Protein: VP2_ROTH3
Sequence: MAYRKRGARRETNLKQDDRMQEKEENKSTNSVIENKNGTKTQLSEKVLSQKEEVITDNQEETRIADEVKKSNKEESKQLLEVLKTKEEHQKEVQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKLFRIFEPKQLPIYRANGEKELRNRWYWKLKRDTLPDGDYDVREYFLNLYDQVLTEMPDYLLLKDMAVENKNSRDAGKVVDSETAAICDAIFQDEETEGVVRRFIAEMRQRVQADQNVVNYPSILHPIDHAFNEYFLQHQLVEPLNNDIIFNYIPERIRNDVNYILNMDRNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKELVSTEAQIQKMSQDLQLEALTIQSETQFLTGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVIPNDMFIRESLVACQLAIINTIIYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFVNNNQFRQVIIDGVLNQVLNDNIRNGHVVNQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLAYNYETLMACITMNMQHVQTLTTEKLQLTSVTSLCMLIGNATVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAANRLNLYQKKMKSIVEDFLKRLQIFDVSRVPDDQMYRLRDRLRLLPVEIRRLDIFNLILMNMEQIERASDKIAQGVIIAYRDMQLERDEMYGYVNIARNLDGFQQINLEELMRTGDYAQITNMLLNNQPVALVGALPFITDSSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWVPTSTTKVYKQVPQQFDFRASMHMLTSNLTFTVYSDLLAFVSADTVEPINAVAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: YQGF_SYNY3
Sequence: MSKKVAALGLDVGRKRIGVAGCDGTGLIATGITTIVRSSYDQDIAQIKQLVEERNVNLLVVGLPYTMAGEIGSQAKQVQKFARRVAEQLHLPLEYMDERLSSVEAENQLKARKRFSSYDKGLIDQQAAEIILQQWLDLRRSHLQEGGDNLHR
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_LACDA
Sequence: MEFQPVFAGAEISIINTLWYLIVFSILLLAVKHYAWGPVKDMMEKRRQKVIDDLDQAASDRKKAETLANEREAALKNSRQEATQILSDAKSNAQKTGKQIVSEAMAEASAIREKAKADAAQAETDALNEAREEVADLSVTIAEKVIAKNLSAADQKDLVDQFIKGLND
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL18_PSE14
Sequence: MTVKKVTRLRRARKARLKMHELEVVRLCVHRSSQHIYAQVISADGSKVLASASTLDKELRDGATGNIDAATKVGKLVAERAKAAGVSQVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SIT4_CANAL
Sequence: MGERGPDQWLEQIKNCISLSESDMKQLCELVKELLMEESNIQPVQSPVTVCGDIHGQFHDLLELFRTAGGLPSDDNQTNFIFLGDYVDRGYFSLETFTLLMVLKVKYPHRITLVRGNHESRQITQVYGFYEECLTKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFCDLVWSDPDNIDTWAVSPRGAGWLFGSKVSREFNHINNLQLIARAHQLVMEGFRYHFKEKDVVTVWSAPNYCYRCGNVASVMQVDEDLEPNFKIFSAVQDGDLSVKNNANKQQRSDYFL
What is the function of this protein?
Serine/threonine protein phosphatase which is involved in the dephosphorylation of the large subunit of RNA polymerase II.  Is required in late G1 for normal G1 cyclin expression, bud initiation and expression of certain genes that are periodically expressed during late G1 (By similarity).  Plays a role during hyphal growth through the regulation of cell wall biogenesis, osmosensing and protein translation.  Involved in virulence in a mouse systemic infection model.
What are the official names of this protein?
Serine/threonine-protein phosphatase SIT4.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.