PharMolix/UniProtQA huggingface dataset:
Protein: PETG_NEOYE
Sequence: MVEPLLSGIVLGLIPITLFGLLVAAYLQYQRGNQLGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL35_DEIDV
Sequence: MPKMKTLKSASRRIKITGTGKVMAFKSGKRHQNTGKSGDEIRGKGKGFVLAKSEWARMKLMLPKGK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ATL59_ARATH
Sequence: MSFIDPRTYIPSNSTESQILKFTFIVCVPICVILIVLLVLYIMRRNSNTNVDWSSLGGFVPTNNNLSTAELGLSKDIREMLPIVIYKESFTVNDTQCSVCLGDYQAEEKLQQMPSCGHTFHMECIDLWLTSHTTCPLCRLSLIPKPSVDLSHQSIEIVSSIENTNGGEASTQPDSQSATEAIIHIDDVEEGNRDSIEVVKESEENDRNSVGTSDGCCSCRLGEKA
What is the function of this protein?
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, and UBC34 in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase ATL59, RING-H2 finger protein ATL59, RING-type E3 ubiquitin transferase ATL59.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RP35_VACCW
Sequence: MQHPREENSIVVELEPSLATFIKQGFNNLVKWPLLNIGIVLSNTSTAVNEEWLTAVEHIPTMKIFYKHIHKILTREMGFLVYLKRSQSERDNYITLYDFDYYIIDKDTNSVTMVDKPTELKETLLHVFQEYRLKSSQTIELIAFSSGTVINEDIVSKLTFLDVEVFNREYNNVKTIIDPDFVFRSPFIVISPMGKLTFFVEVYSWFDFKSCLKDIIDFLEGALIANIHNHMIKVGNCDETVSSYNPESGMLFVNDLMTMNIVNFFGCNSRLESYHRFDMTKVDVELFIKALSDACKKILSASNRL
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of D6 and A7, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 35 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 35 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: MEP4_ARTOC
Sequence: MHGLLLAGLLALPSNVLGHPAEPPNSVNVTHRHIDTSAYFLPQLSLYNKSEDVAEYGGDNITGSSYSGGDHSASNLSSEDYVTVATSLLKATLPYASFRLIDDHYIGDSGIGHVHFRQTVYGIDIDNTDFNVNVGRDGKVFSYGSSFYEGEIPKANPVAKRDFSDPVNALIGAINTLNIPVTAAVGEVKTTPIEGNSTYMFKGTTGALTDPTAQLVYLQKDGGLHLTWRVETDVGDNWLLTYVDAKKNDQVHGVVDYVASAEYQVYPWGVNDPTDGERAHLYFPWFKTGSRNWHIDGRGWHTTTRGNNAIAQDNPSGGWEYEDNHRPTNPLLIFRYPYTQSMTPPASYRDASITQLFYTGNVYHDLLYILGFNEKAGNFQVNNWGKGGKGNDFTILNTQDGSGVNNANFATPPDGQPGRMRMYVWDTSTPYRDGSFEAGIVIHEYTHGVSNRLTGGPANSRCLSSLESGGMGEGWSDFFATVVHLKERDTRNKNYTIGEWASGRQGGIRKYPYSTDLHTNPLMYVDADGLESVHAIGTIWCTILNEVLWNLIERHGMGNVNKIKPTFKDGVPTDGRNLAMKLVLDGMALQPCLPNFVQARDAIIDADMNLTKGANRCELWKAFAKRGLGVGAAYNPEKRVGSSRVPGGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 4, Fungalysin MEP4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GEP5_YEAS8
Sequence: MASQVNALLLPVIESTPLHQITKVALTTTLTSKQSDYKFKEIAVPLTKSLQLYEKAQRRQDLRASLKALESIIYQTHFQWNNPLPRHAHLFQKHYHFLLTHWPFENHRDLVDSIAVNNGKLNSTSSRSVWLKADWITLFNVKNPWVQTPPSLMRLSGTDLDTFTPERIFLINSLGNHYKFLIANSHLSYNHKKYPSPGVQIPIRNALGEVSPAKQIAQLFARQLSHIYKSLFIENPPLSPENELALTAVFYDETVERRLRRLYMRACARAYTTTNADSTTEPLMFHCTRWEVD
What is the function of this protein?
Essential for respiratory growth and required for maintenance of mtDNA.  Required for cell survival in the absence of prohibitins (By similarity).
What are the official names of this protein?
Genetic interactor of prohibitin 5, mitochondrial, Required for respiratory growth protein 5.
What is the protein family that this protein belongs to?
Belongs to the GEP5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPMA_ACTP2
Sequence: MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGQKLKAAGYEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDAADPNSAHNDRRYAHLPKDVIPNAENLKITLERVLPFWEDQIAPALLSGKRVLVTAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNFVEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AMDL_CAEEL
Sequence: MNDRISINLIYLVLTFCCVSAATVRTAKNDDIQKFTIQMIGYSPQKTDDYVAVSIEATPGYVVAFEPMAHADRVHHMLLYGCTMPASEQGFWRGMETCGWGGGSYILYAWARNAPNLVLPKDVAFSVGHEQDGIKYFVLQVHYAQPFAGEVHDFSGVTMHISQKKPMNLAAVMLFVSGTPIPPQLPAFQNNITCMFESSTPIHPFAFRTHTHAMGRLVSAFFKHDGHWTKIGKRNPQWPQLFEGIPSKLMIGSGDQMSASCRFDSMDKNRTVNMGAMGVDEMCNFYMMFHYDAKLDNPYPQGAICAKDYPSKMIDYPKDGFELLPSRPELEHHAHQSKVPFGIVQEAIHENLGGVKLGQVAGLAFNNEQQLLVFQRAGRVWDASTFDNYNILLDKKPIADPVILVISYSGNQTKLERKLGGGQFYLPHGIYVDKDGFVYTTDVGSHTVAKWKIEGNELKNIWTSGELLMPGSDQHHYCKPTGITRVEDQLYVTDGYCNSRVVVLDLNGKRIRQFGLPGEDAGQFNLPHDIVSDSAGRLLVTDRENGRVQHMTTQGHVIEEFKSTMFTNIYSAASHEDYVFMVPGRPIMGHETEGIAVFVGRSGTGLIEYAFGPTTKGKREQMGPQFGQPHCLRVCPDGGHIFVGDIAEGKARLWQFKIRHDQN
What is the function of this protein?
Probable bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides.  The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part.  C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
What are the official names of this protein?
Probable peptidyl-glycine alpha-amidating monooxygenase pamn-1, PAM.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF4A_DROME
Sequence: MDDRNEIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.  Involved in germ cell formation.
What are the official names of this protein?
Eukaryotic initiation factor 4A, ATP-dependent RNA helicase eIF4A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: DDL_ARATH
Sequence: MAPSSRSPSPRTKRLRRARGEKEIGRSREREDDGREREKRNSRERDRDIGRDRDRERKGEGERDREVGDKRRRSGREDTEKRRRTRTDDERYSRGRHERSTSPSDRSHRSSRRSPERAIASRHDEGSNARGGSEEPNVEEDSVARMRAVEEALAAKKKEEPSFELSGKLAEETNRYRGITLLFNEPPEARKPSERWRLYVFKDGEPLNEPLCLHRQSCYLFGRERRIADIPTDHPSCSKQHAVIQYREMEKEKPDGMMGKQVKPYIMDLGSTNKTYINESPIEPQRYYELFEKDTIKFGNSSREYVLLHENSAE
What is the function of this protein?
Involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis.  May facilitate DCL1 to access or recognize primary miRNAs.  Binds RNA non-specifically.
What are the official names of this protein?
FHA domain-containing protein DDL, Protein DAWDLE.
Protein: HMP_RHIME
Sequence: MLTQKTKDIVKATAPVLAQHGYAIIQHFYKRMFQAHPELKNIFNMAHQERGEQQQALARAVYAYAANIENPESLSAVLKDIAHKHASLGVRPEQYPIVGEHLLASIKEVLGDAATDEIISAWAQAYGNLADILAGMESELYERSEERAGGWAGWRRFIVREKNPESDVITSFVLEPADGGPVADFEPGQYTSVAVQVPKLGYQQIRQYSLSDSPNGRSYRISVKREDGGLGTPGYVSSLLHDEINVGDELKLAAPYGNFYIDVSATTPIVLISGGVGLTPMVSMLKKALQTPPRKVVFVHGARNSAVHAMRDRLKEASRTYPDFKLFIFYDEPLPTDIEGRDYDFAGLVDVEKVKDSILLDDADYYICGPVPFMRMQHDKLLGLGITEARIHYEVFGPDLFAE
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: Y5714_PSEA8
Sequence: MSIRDWPEAERPREKLLEQGAAALSDAELLAIFLRTGVTGCSAVELSRRLLSEFGGLRALLEADLASFCGHLGLGVAKYAQLQAVLEMGRRHLAERLRRDSILESPQAVRDYLKARLRHEQHEVFACLFLDTRHRVLAFEVLFQGSIDGASVYPRQVVKRTLAHNAAALILTHNHPSGDARPSLADRQLTARLKEALALIDVRVLDHFIIGDGEPLSLAEYGWL
What are the official names of this protein?
UPF0758 protein PLES_57141.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PDXA_RHOPT
Sequence: MTGMAKPLALTLGEPAGIGPDIALAAWLKREQHGLPPFYLLGDAGCLSRCAKLLGLDVPLAEVKAEDAAAAFATTLPVVSTGQIATATPGQPDATSAPAAIASIEHAVADVRSGRAAAVVTNPIAKSVLYQAGFHHPGHTEFLAELAKRDGIVPQPVMMLWCPALAVVPVTIHVSLRDAITQLTTDLIVSTARIVVKDLRERLGIAQPRLALAGLNPHAGEDGALGQEDRAVVAPAVAILRREGVDARGPLPADTMFHAAARKTYDCAICMYHDQALIPIKTIAFDEGVNVTLGLPFIRTSPDHGTAFDIAGSGQANPSSLIAALKLAAQMASAKTA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A85C_MYCTO
Sequence: MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85C, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex C, 85C, Ag85C, Fibronectin-binding protein C, Fbps C.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_ECOUT
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DCUP_CAMJR
Sequence: MIFIDACFKKPTPYTPIWMMRQAGRYLPEYMEVRKQAGDFLSLCKDYKKASEVSLQPIDILDVDAAIIFSDILVVPLEMGMNLRFEKGEGPVFDNPISTLEDLEKLDDQNAHKKLNYVYDALKLTREKLSQNKALIGFCGSPWTIATYMIEGSGSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGANAIQIFDSWASALEYDKFFEFSFNYMLEISNFIKSKYPNIPVILFPKGISGYLDRIDGNFDVFGVDWSTPLDLARDKLSHKYTLQGNMEPCRLYDKNAIKEGVGKILKTMQNKAHIFNLGHGILPDIPVENAKYFIKLVQESSAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_NITEU
Sequence: MAIAKAEILESIANMTVLELSELIKEMEEKFGVSAAAATVAVAAAPAAAAAVEEQTEFSVILTAAGDNKVNVIKVVRAVTGLGLKEAKDLVDGAPKTVKEGISKEDAESLKKQLVEAGAGCEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PVK1_SUPDI
Sequence: GSSGLIAMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, SupDi-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y759_RICBR
Sequence: MVKSYWKKFWGSNVTKSQHFIELNDIAYGNAKKIRVGIDAYRENVIVYRCVNLIAQSAGHVPWKVLKSKSGEVIANHPLNNLLKRPNPEKAGADFFSELISSMLLFGNSYILSTSDFRPKEIYLLPASATEAVLDQNVLVAYKYQSASGDKLYRIDPISKISRVLHLKNYHPTNHHYGLSSLEAASLPIDLHQQSSYWNHSLLQNGARPSGALIVKDSNGYLSDEQFERLQAQLSEKFTGSNNAGKPLLLEGGLGWQEMSINPKDMDFIQSKNSAAREIALAFGVPPQLLGINGDNTYSNMQEARLALWEETLIPLLDKIADNISNWFSYLFNEEITIDFDSDSISALTEKRENLWAKIANANFMTLNEKRAFVGLPKIKDGDSL
What are the official names of this protein?
Uncharacterized protein RBE_0759.
What is the protein family that this protein belongs to?
Belongs to the phage portal family. HK97 subfamily.
Protein: RECR_STRCO
Sequence: MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQAEPVDVRRLAQALMEVKAKVRFCATCGNVAQEEQCNICRDTRRDPSVICVVEEPKDVVAIERTREFRGRYHVLGGAISPIDGVGPDDLRIRELLARLADGSVTELILATDPNLEGEATATYLARMIKPMGLKVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FPRB_MYCTU
Sequence: MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSAIAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDHQNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDFNDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVAARRGPAHSAFTLPELIGLTAGADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDELRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVADFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEMLAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL
What are the official names of this protein?
Probable ferredoxin/ferredoxin--NADP reductase, FNR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ferredoxin--NADP reductase family.
Protein: MURI_RALPJ
Sequence: MTTRAQAPVGVFDSGLGGLSVLRAIRAELPAESLLYLADSRHAPYGEKSPEYIADRTLRVCEWLVDQGCKALVIACNTATAQAVHVLREKLAVPVIGVEPGLKPAVATSKSRVVGVLATESTLRSEKFARLLAGASGDCKVLSQPGYGLVPLIERGDTHSPAVLELLRAYLQPMLDANADTLVLGCTHYPFLEDAIHEIAGDRLTLIDTGHAVARHLGRTLAAAGLQASGQAATPCFMSTGDVLPLQAMVAALLGEAPMAQRVDIGDAPLSPVAVSLASQPE
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SSRP_SHEB9
Sequence: MVKKNSSKAAPATIARNKRATFEYRFEEKMEAGLSLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPLRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FETP_ALISL
Sequence: MSRTVFCVLLNKEADGLDFQLYPGELGKRIFDNISKEAWGQWQHKQTMLINEKKLNMMDPEHRKMLETEMEGFLFDGKDVVIDGYTPPSK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: ATPE_SALPA
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKAEEHIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CA210_MOUSE
Sequence: MIGGNTTIISGAINASTEAPGLGTGGRAWPVLVGVVLGAVVLSILIALAAKCHLCRRYHASYRHRPLSSAGGGNRPPVGEDEDDDGFIEDNYIQPGAGEMETTGSRDHFSL
What is the function of this protein?
May be involved in membrane trafficking between endosomes and plasma membrane.
What are the official names of this protein?
Type III endosome membrane protein TEMP, TEMP.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein. Early endosome. Recycling endosome. Cell membrane. Note=Also localizes to tubular endosome structures.
Protein: GLGX_DICCH
Sequence: MGELLAGRPRPLGSHFDGEGVNFALFSSGASRVELCIFDGLREQRLPLTARTGDIWHGYLPDAQPGLCYGYRVDGAFDPSRGQRFNANKLLLDPCARQMDGWVVDDQRLHGGYHQPDPSDSAEVMPPSVVVDEHYDWQGDRLPRTPWSQTVLYEAHVRGLTRRHPGIPAAIRGTYAALAHPVMLDYLTQLGVTALELMPVQQHADEPRLQSMGLRNYWGYNTLLPFAVDNSLAASDDPLNEFRDTVRALHQAGIEVILDVVFNHSAELDVDGPTLTLRGIDNASYYWLTENGDYHNWAGCGNVLRLEHPAVLHWVIECLTFWHEVCHVDGFRFDLATILGRLPDFSSSAPFFTALRNHRSLRDCKLIAEPWDISPGGYQLGQFPAPFAEWNDRFRDDMRRFWLHGDLPIGVLARRFAASSEVFERGSRQPWASVNMLTSHDGFTLRDLVCFNHKHNDANGEQNRDGTNSNFSFNHGTEGLEADETTQARRRVSQQALLTTLLLSQGTPMLLAGDEFGNSQQGNNNAYCQDNALAWLHWDQADDALLAFTSGLIRLRRSIPALQRGRWWRDDDEDDVRWLNAQGEALTPYEWEQGTHQLQIQLSERWLLLVNATPQVSDFSLPEGEWRVAPPFSATDHLLDGQTWRGQANAVCVLVKQ
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin (By similarity).  Hydrolyzes the alpha-1,6-glycosidic linkages in amylopectin while does not hydrolyze the alpha-1,4-glycosidic linkages in amylose.  Native glycogen is a poor substrate (PubMed:11554733).
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM_RABIT
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.  Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.  Is a regulator of voltage-dependent L-type calcium channels.  Mediates calcium-dependent inactivation of CACNA1C.  Positively regulates calcium-activated potassium channel activity of KCNN2.  Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding.  Acts as a sensor to modulate the endoplasmic reticulum contacts with other organelles mediated by VMP1:ATP2A2.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
Protein: RL30_PSEFA
Sequence: ATVKVTLIKSVTGRIPNHKLXVKGL
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.