PharMolix/UniProtQA huggingface dataset:
Protein: EFG_MYCAP
Sequence: MARQHKLEDYRNIGIMAHIDAGKTTTTERILLHTGKIHKIGETHDGASQMDWMAQEQERGITITSAATTAFWKGKRINIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYRVPRLIYVNKMDKAGADFFASVKSVKTRLNANAVAIQIPIGQESDFKGIVDLVEMKAYEYDGKPEENAKEIEIPFDLQALAKEKRQELIEAVATYDEEFMMKVLDGVEPTLDELKAMIRKATLTSEFFPAVCGTSFKNKGVKKMIDAVVDYLPSPLDIPAAKAHKGENEEVDVPATDDYPFTGLAFKVMTDPFVGSLTFIRLYAGTLQKGSYVYNSTKGTKERIGRLILMHANSRSEIDEANAGDIVAAVGLKGTTTGDTLIAEKAPEIVLERMVFPEPVISQALEPESKDAMEKLALGLQKLAAEDPTFRTYTDEETGQTIIAGMGELHLDIIVDRLKREHGVKAKVGAPQVSYRETITKSADVEGKHIKQSGGKGQYGHVWIKFEPNPDKGFEFVDKIVGGKIPKEYIKPIQKGLEDKMASGILAGYPMIDIKATLFDGSYHDVDSSELAYKIAASKALTKAKDLVGTVLLEPIMDVSVIIPDDYYGDVMGDITRRRGQIQESELRNDGDHILRCLTPLSEMFGYATDLRSMTAGRGNYQMQFHHYEKCPKNIADEIIKKRNIQLKDED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNAA_ECOSE
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RRF_JANSC
Sequence: MSDDFMLDTDDLERRMEGAIASLRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVNVPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTIIMLPIPELNEERRRELTKVAGTYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_MYCGA
Sequence: MSKIKTLRLEATIHKLLSQAISTEINNSLIKTSVITAIKLSDDKSVAKIYIDCLIPNNIAKTLQAYKDATGVFRHVLSKHLTIRRIPQLVFYYDDSISKGAKIDQILAEIKQEKKENHE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_ANTLO
Sequence: WDRHGVPVEYEIDKALGITGVKDIHDMGIRKYNKECRKIVLRYTKEWEAVVKRMGRWIDFRNGYRTMDRSFMESIWHIFKMLYEKGSVYRGHRVMPYSTACSTPLSNFEANQNYKDVSDPSILVAFPLRKPFKGYSLSLVAWTTTPWTLPSHMAILVNQSFIYAIFRLKSAFFIMQRDRVNVYFKDAVVISEVKGHELLHLEHDQPFMYYNHYREKGFFRVYHADFVSEIDGTGVVHCSPGFGEDDYKAMTMPGLIKENELLPSPLDENGRFNEEVPEYKGMHVKDADQSIIKDLGKKILYEGKVYHRYPFCWRSDTPLIYKLVPNWFVRVKREIPRLLESNSTINWIPESIGEHKFKNWLSEARDWSISRNRFWGTPIPLWHCDGKYICIGSIEELSRLSGRKIDDIHRENVDDVVICKDGEKYRRIEEVFDCWFESGCMPYAQRHWPFECDNLCLPADFVAEGVDQTRGWFYTMHVISTVLLAKPRFRNCIVNGIVLASDKKKMSKRLKNYPDPMDVINRYSADSLRLYLISSPVVMAENMCFSEEGVGEVLKTLLIPWYNCIYFYSECPNAGDQEQTRMDDWILNTLNTFGNKVKRDMSKYMLQGVMGYATSFVNDLSNWYIRLN
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: PANC_BORBR
Sequence: MKVVHTIQDLRDHLRGQNRVAFVPTMGNLHEGHLALMKLARQHGDPVVTSIFVNRLQFGPNEDFDRYPRTLPDDVAKMERDRDVYLVFAPDEREMYPEPQNYRVLPPDDLGDILEGEFRPGFFTGVCTVVMKLLACVQPRVAVFGKKDYQQLMVVRNMCRQLQLPVEILAHETVRADDGLALSSRNRYLSEAERAEAPVLYETLRGIAQRRAGGEQDPAALERVAAQALADRGWKVDYVAVRRQRDLKAPDVAEMSAGEPLVALAAAKLGATRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA18_CONBE
Sequence: PDGRNAAAKAFDLITPTVRKGCCSNPACILNNPNQCG
What is the function of this protein?
Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them.
What are the official names of this protein?
Conotoxin Bt1.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_CHLCH
Sequence: MSNENKVLKLGLPKGSLQDSTIDLFAQAGFHFSVQSRSYFPSIDDDELEAILIRAQEMAHYVELGAFDVGLTGKDWIIETDADVVEVADLVYSKASMRPVRWVLCVPESSSIQSVKDLEGKHIATEVVNITKKYLAQHGVNASVEFSWGATEVKPPDLADAIVEVTETGTSLRANKLRIIDTLLESNTKLIANRQSWEDPWKREKIENMAMLLLGAINAHGKVGLKMNAPKASLEKLMSIIPALRQPTISALADAEWVALEVIVTEKIVRKLIPELKRAGAEGIFEYNINKLID
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_AROAE
Sequence: MAHQKILILDFGSQVTQLIARRVREQQVYCEIHPFDVSDDFVREFAPAGVILSGGPNSVYEAVGWHAPQSVFELGVPVLGICYGMQTMAQQLGGSVESSGKREFGYAEIRARGHSELFRSIEDRTNDEGHGLLDVWMSHGDKVTALPPGFKVIASNESCPVAGMADEVRKFYAVQFHPEVTHTIKGRDMLARFVHEICGCGRDWNMPDYVNEAIEKVRAQVGQEEVILGLSGGVDSSVVAALLHRAIGEQLTCVFVDNGLLRLNEAEQVMLTFARNLGVKVIHVDATEQFMGHLKGVSDPEAKRKIIGREFVEVFQAEANKLPNAKWLAQGTIYPDVIESAGSKTGKAHTIKSHHNVGGLPETLNLKLLEPLRELFKDEVRELGIALGLPHEMVYRHPFPGPGLGVRILGEVKQEFAELLRRADAIFIDELRAADWYDKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVETQDFMTAHWAELPHSLLGKVSNRIINEVRGINRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GASR_HUMAN
Sequence: MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
What is the function of this protein?
Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
What are the official names of this protein?
Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREG_RHOPA
Sequence: MSDHHGPLRVGIGGPVGSGKTALMDLLCKSMRERYDIAAITNDIYTKWDAEFLVRSGSLTPDRIAGVETGGCPHTAIREDASMNLAAVAEMRSKFPGLDLVLIESGGDNLAATFSPELADITIYVIDVAAGDKIPSKGGPGITRSDLLVINKIDLAPYVGASLEKMDTDAKRMRGARPFVMTNLKKSEGLDRIIGFIEEKGGLTPRRSA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMOT_MOUSE
Sequence: MRSSDDQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNSSPFSTGSGNQGPQNDVLSSQDHHQQQLVAHPARQEPQGQEIQSENGVMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLTPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNATSSSEFYKAQGPPPSQHSLKGMEHRGPPPEYPFKGVPSQSVVCKSQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARATQDISSLSLSARNSQPHSPTSSLTAGASSLPLLQSPPSTRLPPGQHLVSNQGDHSAHLSRHQQHLLSSQSHQGDHYRHAQASLTSAQQQPGEAYSAMPRAQQSASYQPMPADPFAMVSRAQQMVEILSDENRNLRQELDGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRDRLETANKQLAEKEYEGSEDTRKTISQLFAKHKENQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNSQPTNASEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSSMRPAKSLMSISNAGSGLLAHSSTLTGAPIMEEKRDDKSWKGSLGVLLGGDYRVEPVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGPESTKTAAVTPISAPMAGPVAAAAPAAAINATAATNTATAATNTTIMVAAAPVAVAAVAAPAAAAATPSPANAAALAAAAAPATSVSAATSVSAANSISPAAPVAPAAVVPPAAPVSPAAAVQIPAAASLTPATVSPTAATATAAVAAATTAAITAAAAAATTAIQVAPATSAPVPSPASIPAPATAQASAPTPTQASTPAPTEPPSPVPTPTPALVQTEGPANPGASSGPRRLSTPNLMCNPDKPDAPAFHSSTLERKTPIQILGQEPDAEMVEYLI
What is the function of this protein?
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions.  Appears to regulate endothelial cell migration and tube formation.  May also play a role in the assembly of endothelial cell-cell junctions (By similarity).
What are the official names of this protein?
Angiomotin.
What is the protein family that this protein belongs to?
Belongs to the angiomotin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein (By similarity).
Protein: THIO2_ECO57
Sequence: MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGETLDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRFGIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL
What is the function of this protein?
Efficient electron donor for the essential enzyme ribonucleotide reductase.  Is also able to reduce the interchain disulfide bridges of insulin (By similarity).
What are the official names of this protein?
Thioredoxin 2, Trx-2, Protein-disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAUR_PARDE
Sequence: MNWDDLRVVAAINRCGSFNRAAKMLNVEETTIARRLARLEGSLGCVLFQAVDGQRRPTEQCRALLQPLVLMEQAAEAITLQLERQERPLRNFRLTTIDAIAQHYLAPTLADLLIAEPELSLQLETSDDNVDMARWHADIAIRLGRPRRGNFTMRRVGEMRFNLVLPRGAAPEDLVLAAYPDPLMEVPEMQDFQQYFPGRQARLRSANLRVIRVLVDSGRAAAVLPDFLSVDLVGDERFQVHRLPARREIWLLAQPHLRDDPLARRVTNWCADLFAETLAGDAV
What is the function of this protein?
Transcriptional activator of the mau genes involved in methylamine metabolism.
What are the official names of this protein?
Mau operon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ATPG_BURP0
Sequence: MAGMKEIRGKIKSVQNTRKITKAMEMVAASKMRRAQERMRAARPYAEKVRAIAAHMSRANPEYRHPFMVANDGVKTAGMILVTTDKGLCGGLNTNVLRASLQKFKELEEQGQKVEATAIGGKGLGFLNRFGAKVISQVVHLGDTPHLDKLIGAVKTQLDLYSEGKLSAVYLAYTRFVNTMKQETVIEQLLPLSSEHFDTNDGTPATSWDYIYEPDAQAVVDELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKTVISELQLSYNKSRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NS1_I34A1
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: IL2_RAT
Sequence: MYSMQLASCVALTLVLLVNSAPTSSPAKETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPKQATELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNIRVTVVKLKGSENKFECQFDDEPATVVEFLRRWIAICQSIISTMTQ
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UGTK4_MANES
Sequence: MGSISPQKPPHAILVPYPAQGHVNPLMQLGKLLHARGFYITFVNTEHNHRRLIRSRGQEFIDGLPDFKFEAIPDGLPYTDRDATQHVPSLSDSTRKHCLAPFIDLIAKLKASPDVPPITCIISDGVMAFAIDAARHFGILEIQFWTTSACGFMAYLHHIELVRRGIVPFKDESFLHDGTLDQPVDFIPGMPNMKLRDMPSFIRVTDVNDIMFDFLGSEAHKSLKADAIILNTFDELEQEVLDAIAARYSKNIYTVGPFILLEKGIPEIKSKAFRSSLWKEDLSCLEWLDKREPDSVVYVNYGCVTTITNEQLNEFAWGLANSKHPFLWIVRPDVVMGESAVLPEEFYEEIKDRGLLVSWVPQDRVLQHPAVGVFLSHCGWNSTIECISGGKPMICWPFFAEQQTNCKYACDVWKTGVELSTNLKREELVSIIKEMMETEIGRERRRRAVEWRKKAEEAISVGGVSYNNFDTFIKEVILQQQTQ
What is the function of this protein?
UDP-glucosyltransferase catalyzing in planta synthesis of cyanogenic glucosides.  Able to glucosylate acetone cyanohydrin and 2-hydroxy-2-methylbutyronitrile, forming linamarin and lotaustralin.  Accepts also to some extent, a wide range of potential acceptor substrates, including simple alcohols, flavonoids, isoflavonoids and other hydroxynitriles such as p-hydroxymandelonitrile, mandelonitrile, (E)-4-hydroxy-2-methylbut-2-enenitrile and (E)- 2-(hydroxymethyl)but-2-enenitrile.
What are the official names of this protein?
Linamarin synthase 1, Cyanohydrin UDP-glucosyltransferase UGT85K4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: GP119_HUMAN
Sequence: MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
What is the function of this protein?
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC).  Functions as a glucose-dependent insulinotropic receptor.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Seems to act through a G(s) mediated pathway.
What are the official names of this protein?
Glucose-dependent insulinotropic receptor, G-protein coupled receptor 119.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCBA_ECOLX
Sequence: MELKASEFGVVLSVDALKLSRQSPLGVGIGGGGGGGGGGSCGGQGGGCGGCSNGCSGGNGGSGGSGSHI
What is the function of this protein?
This glycine-rich peptide antibiotic inhibits DNA replication in many enteric bacteria, that leads to induction of the SOS repair system, massive DNA degradation and cell death.  B17 inhibits type II topoisomerase by trapping an enzyme - DNA cleavable complex.
What are the official names of this protein?
Bacteriocin microcin B17, MccB17.
Protein: DNAB_HELPJ
Sequence: MDHLKHLQQLQNIERIVLSGIVLANHKIEEIHSVLEPSDFYYPPHGLFFEIALKLHEVNCPIDENFIRQKMPKDKQISEDDLVAIFAASPIDNIEAYVEEIKNASIKRKLFTLANTIREQALESAQKSSDILNAVEREVYALLNGSTIEGFRGIKEVLESTMNLITENQRKGSLKVTGIPTGFVQLDNYTSGFNQGSLVILGARPSMGKTSLMMNMVLSALNDDRGVAVFSLEMSAEQLALRALSDLTSINMHDLESARLDDDQWENLAKCFDHLSQKKLFFYDKSYVRMDQIRLQLRKLKSQHKELGIAFIDYLQLMSGNKATKERHEQIAEISRELKTLARELEIPIIALVQLNRSLENRDDKRPILSDIKDSGGIEQDADIVLFLYRGYIYQMRAEDNKIDKLKKEGKVEEAQELHLKVNEERRIHKQNGSIEEAEIIVAKNRNGATGTVYTRFNAPFTRYEDMPVDSHLEEGQETKFEMPTT
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: S38A1_RAT
Sequence: MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEETFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKNTQRIWAALFLALGVLFSLISIPLVIYDWACSSSNGEGH
What is the function of this protein?
Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:10660562, PubMed:11692272, PubMed:11756489, PubMed:12684517).  The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient (PubMed:11692272, PubMed:11756489, PubMed:12684517).  Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis (PubMed:11756489, PubMed:10660562).  May also contributes to amino acid transport in placental trophoblast (By similarity).  Regulates synaptic plasticity (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid symporter 1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System A transporter 2, System N amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain.
Protein: ASTB_CHRSD
Sequence: MSQDVREVNFDGLVGPTHNYAGLAHGNVASMRHGGLTANPREAALQGLAKMKSLMEAGFAQGVLPPQQRPDLGALRDLGFTGDDAGVLAQAARQAPQLLRAVCSASSMWTANAATVTPSLDAPDGRVHFTAANLQSSFHRYLEPRTTARVLAAMFHDPAHFAHHPVLPATPTFSDEGAANHTRLCGDHDEPGVHLYVYGRQAFGGEHGPKRYPARQTLEASQAIARQHGLDDTRTVFAQQHPDAIDAGVFHNDVIAVGNGPVLLYHEMAFRDETATLEALRARMSTPLIPVRVPSEAISLEDAVATYLFNSQLLSNPDGSMTLVVPGECQENETVWRTIQDLLLGGNNPISEVLVKDVKQSMRNGGGPACLRLRVALAARERQALTGRVLLDEALHDDLAAWVERHYRDRLAPEDLADPLLVRESLTALDELTQLLGIGAVYPFQLN
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: RL1_TOLAT
Sequence: MAKLTKRMRVIREKVDATKEYGITEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPNGTGRTVRVAVFTQGANAEAATAAGADLVGMEDLAEQVKRGELNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHSTIGKVDFTEAQLKENLESLLVALKKAKPSTSKGQFIKKVSLSTTMGAGMAVDQASLDTKAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.