PharMolix/UniProtQA huggingface dataset:
Protein: NDUS3_SOLTU
Sequence: MDNQFIFKYSWETLPKKWVKKMERSEHGNRFDTNTDYLFQLLCFMKLHTYTRVQVLIDICGVDYPSRKQRFEVVYNLLSIRYNSRIRVQTSADEVTRISSVVSLFPSAGWWEREVWDMFGVFSINHPDLRRILTDYGFEGHPLRKDFPLSGYVEVRYDDPEKRVVSEPIEMTQEFRYFDFASPWEQRSDG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, Complex I-27kD, CI-27kD, NADH dehydrogenase subunit 9, NADH-ubiquinone oxidoreductase 27 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RLMD_PSE14
Sequence: MAKHERGLRFQPAGGVKTVQIPAGKKQRLTIERLSDDGRGIAFLEGKTWFVAGSLAGEEVEARVLNARGKVVEARTERVFTASTMRRAPACEYFGRCGGCSVQHVPHEEQLALKQRMLAEQLLRVANVVPDEWAAPLSGAELAYRRRARVAVRWDAKAKRLDVGFRAAASQDIVSIEHCPVLVQALQPIMNELPGMLKNFSKPQALGHVELFSGVATAVLLRHTAPLAEADLALLQAFCSKHGAQLWLHGEGEPQPVSPGDTLGYRLEPWNLQLAWRPGDFIQVNAAVNTAMIEQALQWLAPAKDERVMDLFCGLGNFALPLAGLAREVVAVEGVATMVERAAVNAMSNDLHNVQFFQADLSQPLTHADWAAEGFSTVLLDPPRDGAFEVVRQIRKTGARRLLYVSCNPATLARDTVELISQGYRLKRAGILDMFPQTAHVEAMALFEMSK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: SH3G1_CHICK
Sequence: MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDLTSKAVTEVLTRTIEYLQPNPASRAKLTMLNTMSKIRGQVKNPGYPQSEGLLGESMIRYGKELGEDSNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCDKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQAMEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPRREYKPKPRETYDFGESDQSNGGFSCTPTPKVSASSSFRSDKPFRTSVRSIPHLDQPCCKALYDFEPENDGELGFKEGDIITLTNQIDENWYEGMINGQSGFFPLNYVEVLVPLPQ
What is the function of this protein?
Implicated in endocytosis.  May recruit other proteins to membranes with high curvature (By similarity).
What are the official names of this protein?
Endophilin-A2, Endophilin-2, SH3 domain-containing GRB2-like protein 2, SH3p8.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein. Cell projection, podosome. Note=Associated with postsynaptic endosomes in hippocampal neurons.
Protein: UVRC_NAUPA
Sequence: MSFSEKIKSLPDQPGIYQYFDENGKLLYIGKAKSLKKRVKSYFRFNPFRPADNLSPRIYKMISEAKDLNYIVVESENDALILENSLIKQLKPKYNILLRDDKTYPYIYIDLDEPFPMPQITRKVVKGKNIKYFGPFSSGASAILKTIYEEIPLVQSKSCLRSGKACLYHQIGRCLAPCEGKVTSREYMKYVDQAIELIHDKEKILEILNQKMQKYAENLQFEEAAEIRDRIKSIESAEIYSHVDLAKLEDLDIFAVEIFNKKAVVIRIFVRQGKVVASSNSVINSQTVPEIGEIYTRAILEFYSTETPFTSSKILVGDDFEEREWLSQVLSEKFGKKISIITPTTKERKSLIKLAKLNALEVIKNQKENTVLDELKILFNLQNTPYKIEVFDTSHMQGEATVGAMVVWEDGKFKKSDYRHYHLEGKDEYSQMRELLTRRAQSFEKSPPPDLWLIDGGKAQLNLAKEIIDSTGANIDVLAISKEKIDAKAHRAKGKAKDKIYFINEKLKVKSEKLNIDKLELSQSDKRLQFLQMLRDEAHRFAIEFHRKTKRKKDTQIDLLQVKGIGKAKMTKLLNYFGSFDNIKKASFDELKDVLNEKDAKAIKEFFKGQK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_CHLAD
Sequence: MNEPMSLFDDLPEEHDEPQEAPERRLPMVVLGEMVIMPHMTIPLQVPQGKSYRAMERAWEEDRDVLLIFVREHQLEGYKSNQPQNLPPIGVIAQLQEFAKLNDGTARVILEGQSRAQIIEAIQITPFYRVRCRPYTDPPVSGLEVEALMETVKQQVDEFVEHLGEVPQEAVQFVHRIDRPGHLADIVTWGPAFDFKDRLEVLNTLDPVERLRKVYLVLARQLELLKLRVKIQQDTKEVLDQSQREYFLREQLRIIRRELGEDEEGDDPIDELRRKIHELDAPEYVKNQALHELKRLAQQGMNNPESGVIRTYLDWILSLPWADEELPEISITEAQKVLDADHYGLEKVKERILEYLAVRKLAGDKMRSPILCFVGPPGVGKTSLGRSIARALGRKFVRTSLGGVRDEAEIRGHRRTYIGAMPGRIIQAMKNAKSKSPVYILDEVDKIGLDFRGDPTSALLEVLDPEQNNAFSDHYLEIPFDLSKVIFIATANQLDPIPLPLRDRMEIIEIGGYTEDEKLEIARGFLIPKQREFHGLTEDQIEFTEGAILKLIREYTREAGVRGLEREIASLCRKVARQVAEQTEANGELPPKFVIDEAAVVKYLGPERYTYGIAEEQDEVGVATGVAWTSAGGDILSIEVLPFKGKGQLQLTGQLGEVMKESAQTAVSYVRSRAADFGIDPNTFEETNIHIHIPEGAVPKDDPSAGITLTTALISALTGTPVRRDVAMTGEVTLRGKVLPIGGLKEKTLAAHRAGIRTFILPKENAKDISELPEKVRRELNLIPVSSMDEVLRIALSRMPTPANNQNGSHTNNRGQPSPAPAGT
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_DESAL
Sequence: MKKIGIFAKVHEEPLEMADQLQKWLVNRDIEVVRRESSPPVLDVTQSNPGHAPADLSCVIVLGGDGTFLSAARWIGNQEIPILGVKFGAVGFLSETRKQDLYPVLESVLKKDFTTQTRTRLLATVREDEKIITTQTVLNDVVINNGTLARLANVNTYVDEEYLTTFRADGLIVATPTGSTAYSLAAGGPILEPQVAAIVLTPICPFTLTNRPLIVTDTSTICMTLAATAMDVTLTFDGQAGLKLNEHHTITIQKAPVPTIMIKVPGQSYFDVLKTKLRWSGGKV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_GEOUR
Sequence: MATKIRLARAGAKRKPFYQVVVADERCKRDGRFIENVGTYDPNQNPAVFKLEEAKTLEWLGKGAQPTDTVKQILKKAGIWEKFVSKLA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL24_PSEE4
Sequence: MQKIRRDDEIIVIAGKDKGKRGKVLKVLADDRLVIGGVNLVKRHTKPNPMAGVQGGIVEKEAPLHASNVAIFNGETNKADRVGFKVEDGKKIRVFKSTQKAVDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MOB2_YEAST
Sequence: MSFFNFKAFGRNSKKNKNQPLNVAQPPAMNTIYSSPHSSNSRLSLRNKHHSPKRHSQTSFPAQKSTPQSQQLTSTTPQSQQQEASERSESQQIMFLSEPFVRTALVKGSFKTIVQLPKYVDLGEWIALNVFEFFTNLNQFYGVVAEYVTPDAYPTMNAGPHTDYLWLDANNRQVSLPASQYIDLALTWINNKVNDKNLFPTKNGLPFPQQFSRDVQRIMVQMFRIFAHIYHHHFDKIVHLSLEAHWNSFFSHFISFAKEFKIIDRKEMAPLLPLIESFEKQGKIIYN
What is the function of this protein?
Functions as an activator subunit for the CBK1 protein kinase.  Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network.  Required for coordinating polarized cell growth during interphase with the onset of mitosis.  Required for mother/daughter cell separation after cytokinesis.  Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit.  It coordinates ACE2-dependent transcription with mitotic exit network activation.
What are the official names of this protein?
CBK1 kinase activator protein MOB2, MPS1 binder 2, Maintenance of ploidy protein MOB2.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the bud cortex during polarized growth and to the bud neck and daughter cell nucleus during late mitosis.
Protein: CODY_STRPI
Sequence: MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_STRPG
Sequence: MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIIEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI
What is the function of this protein?
Antitumor protein.  Has a powerful and dose-dependent inhibitory effect on antigen, superantigen, or mitogen-stimulated human peripheral blood mononuclear cell (PBMC) proliferation.  It may inhibit cell proliferation by arresting cell cycle and inducing apoptosis.
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD, Streptococcal acid glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_ANASK
Sequence: MDLVTRRIRGALGIAGPLLFLEGVPRARLGEVVRIRGEPEAHGRAAEERSGQVIALSRDRIAVQVLEETRGLAPARAEVTLTGQVARLGVSRGMLGRVLDGLGRPADGLPPPVPEARPAIHGAALNVTRREKPSDFIETGVSAIDGMNTLVRGQKLPVFSCAGLPASRLAAQIVCQARVRGGEPFAVVFAAMGSPFREYHAFLDAFRAAGVLDRTVVFLNRAEDPPIERLMTPRCALTCAEHLAFAHGLHVLVVLTDVTSYCEALREVALAREEVPGRRGYPGYMYTDLATIFERAGRVRGRPGSLTQLPVLTMPDDDLTHPIPDLTGYITEGQIVLSRDLDRRGVYPPIDVLPSLSRLMGLGAGPGKTRDDHRPVADQLYAFYARGRDVRRMAAIVGAANLGEEEKRLLAFADAFEDELVGQGGTFRTIEDTLEAGWRLLSGFPPAALTRIPERLLRARPARPAAGAAALSGGAVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: GATB_CHLPB
Sequence: MSYELVVGLEVHCQLNTNSKAFCGCSTEFGKPANTNVCPVCLALPGALPVLNRRVVEDAVKLGLATDCTVARQSILARKNYFYPDLPKGYQISQFEEPICSEGMVFVDTDEGRKNIRLVRIHIEEDAGKSIHDIGDDTFIDVNRCGVPLLEIVSYPDIRSAGEASSYLQKLRQIIKYLGISDGNMEEGSLRCDANVSVRLTGAEEYGTRTEIKNMNSFKNVEKAIEYEAKRHIDVLENGGTIFQETRLWDADRQETRSMRGKEFAHDYRYFPDPDLVPIEVDEEMLDRLKQELPELPEVRAERFVRETGIPAYDAGVLTSEREVADYFEKVVRACGDAKAASNWVMGEVLRTLKEKNIPVALFSVSPERLGGLLNLIGKGTISTTIAKQVFERMLETGDDAAAIVEKEGLAQISDTTEIETLVQDIIEANPGQVEQYRSGKTRIFGFFVGQCMKAMKGKANPVVVNEILKQKLDG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: YGGU_ECO8A
Sequence: MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: ODO1_BRUA1
Sequence: MAKQEQAPDRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNVLGLEYATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRMKADWRQKLEGEFEAGQSYKPNKADWLDGAWAGLRTADNADEQRRGKTAVPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEGHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYEYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: DER_DEIGD
Sequence: MQKVAIVGRPNVGKSSLFNRLVGRREAVVADFPGVTRDAKEGLMLYHNHRIVLVDTGGLWSGDEWEQAIREKAEWAMEGAQAVIFVVDPREGLTAADYEVADWLRRLGKPVIVAANKIDSPKHDVYLAELWGLGFGDPVAISAEHARGLDDLMERVMAHLPADEEDVPEVAPIRISLIGRPNVGKSSLLNAITQSERAIVADQPGTTRDSLDVEWNYGGQRFVLVDTAGIRKKPDTAIEEYAIQRSEAAIERSDIIWLVVNATEIGDHELKLANLAYDSGKPVIVVVNKWDLVPDEALKQTEKELNQKLHHIAYAPRVYTSAINDYGIHDMLAEAMKLYEKWQSRIPTAELNRWLEIWQMRQAVPNFHGKPLKMYFMTQVETAPPTFAIFCNRADFVTRAYEGFLQNRIREDLGLAGIPVRLKWKEKGPYKKGKKGEEAEA
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ANX2A_XENLA
Sequence: MALIHEILGKLSLEGNQSCARQSALGTVKASTNFDAEKDAAAIETAIKTKGVDELTIINILTNRSNDQRQDIAFAYHRRTKKDLASALKGALSGNLETVMLGLIKTRPQYDASELKASMKGLGTDEDTLIEIICSRTNKELLDIQNAYRELYKTELEKDIVSDTSGDFRKLMVALAKGKRQEEGSVVDYEKIDQDARELYEAGVKRKGTDVGKWITIMTERSTPHLQKVFERYKSYSPYDMEESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYESMKGRGTKDKILIRTMVSRSELDMLKIRKEFKKKYGKSLHYFIGQDTKGDYQRALFNLCGGDD
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity.
What are the official names of this protein?
Annexin A2-A, Annexin II type I, Annexin-2-A, Calpactin I heavy chain, Calpactin-1 heavy chain, Lipocortin II.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In the lamina beneath the plasma membrane.
Protein: ASQG_EMENI
Sequence: MAAFTVIIIGGSISGLTLANVLEKYGIKYILLEKRPSIGPQLGATVVVHPSGLHLLSQLGLRERVEELATPVELQKAIGPDGTFVLNIAATNQCDRTIADALSTGYMPMFIARQDLIKVLYDNLQDKFRVHASLGLRELEWAGDKVKVTTTDGTSVVGDIVVGADGANSRTRAEIWKIADVEDPSYGSQQLAKSIACTYRCVFGMVDDGDSSLARTAYLAFQYNRAYTYLPTDSGRAYFLAFFKNPAKTVNDAIPRYSDQDEDADVAAHANDIIVPGLTFGDLYKRRTRCTLVPLQEYLLDKCFYKRVVLIGDAVHKLNPITGRGANLAIEGAALLGDLIKHALEKSLQPTDEMLQTAFFTYQQCTKSRAPSQIDDAHRVQSLAALENPLLKFMSLKLLKRATADKLALGVAVDFSTGHSMRYLPQLPQRGMVPLNKDVVANPEHRPASSTVLWIILMLGMASLGAVWQKHQRAEEDQPIHGYTLLTLSTFYNLMILFASAVHGSLGRRAVNLSFSDDSGMVPFYAVGHAPDKYRPTTPSRRVGLLVPGPSYLGSGGHFNGLLEVA
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the aspoquinolone mycotoxins (PubMed:25251934, PubMed:28114276).  Within the pathway, the FAD-dependent monooxygenase asqG catalyzes the epoxidation of the terminal C7'-C8' olefin to produce the intermediate [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B (PubMed:28114276).  The first step of the pathway is catalyzed by the nonribosomal pepdide synthetase asqK that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin.  4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase asqJ.  AsqJ also converts its first product 4'-methoxydehydrocyclopeptin to 4'-methoxycyclopenin.  The following conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase asqI.  4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B.  The prenyltransferase asqH1 then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase asqF to yield conjugated aryl diene.  The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase asqH2 to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain.  The FAD-dependent monooxygenase asqG performs epoxidation of the terminal C7'-C8' olefin.  Finally, after dehydratation of the epoxide at C3 by asqC, the quinolone epoxide rearrangement protein asqO catalyzes an enzymatic 3-exo-tet cyclization to yield the cyclopropyl-THF ring system in aspoquinolone (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase asqG, 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster protein asqG, Aspoquinolone biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS13_ACTP2
Sequence: MARIAGINIPDQKHTVIALTAIYGIGKTRAKAICAVTGIAEDVKIRELSEEQIEKLREEVGKFTVEGDLRREVTLSIKRLLDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PSBJ_NASOF
Sequence: MADTTGRIPLWVIGTVAGIPVIGLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YL67A_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKKFQIPYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
UPF0479 membrane protein YLL067W-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BGLA_ASPFN
Sequence: MKLGWIEVAALAAASVVSAKDDLAYSPPFYPSPWADGQGEWAEVYKRAVDIVSQMTLTEKVNLTTGTGWQLERCVGQTGSVPRLNIPSLCLQDSPLGIRFSDYNSAFPAGVNVAATWDKTLAYLRGQAMGEEFSDKGIDVQLGPAAGPLGAHPDGGRNWEGFSPDPALTGVLFAETIRGIQDAGVIATAKHYIMNEQEHFRQQPEAAGYGFNVSDSLSSNVDDKTMHELYLWPFADAVRAGVGAVMCSYNQINNSYGCENSETLNKLLKAELGFQGFVMSDWTAHHSGVGAALAGLDMSMPGDVTFDSGTSFWGANLTVGVLNGTIPQWRVDDMAVRIMAAYYKVGRDTKYTPPNFSSWTRDEYGFAHNHVSEGAYERVNEFVDVQRDHADLIRRIGAQSTVLLKNKGALPLSRKEKLVALLGEDAGSNSWGANGCDDRGCDNGTLAMAWGSGTANFPYLVTPEQAIQNEVLQGRGNVFAVTDSWALDKIAAAARQASVSLVFVNSDSGEGYLSVDGNEGDRNNITLWKNGDNVVKTAAENCNNTVVIIHSVGPVLIDEWYDHPNVTGILWAGLPGQESGNSIADVLYGRVNPGAKSPFTWGKTRESYGSPLVKDANNGNGAPQSDFTQGVFIDYRHFDKFNETPIYEFGYGLSYTTFELSDLHVQPLNASRYTPTSGMTEAAKNFGEIGDASEYVYPEGLERIHEFIYPWINSTDLKASSDDSNYGWEDSKYIPEGATDGSAQPLLPASGGAGGNPGLYEDLFRVSVKVKNTGNVAGDEVPQLYVSLGGPNEPKVVLRKFERIHLAPSQEAVWTTTLTRRDLANWDVSAQDWTVTPYPKTIYVGNSSRKLPLQASLPKAQ
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase A, Beta-D-glucoside glucohydrolase A, Cellobiase A, Gentiobiase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_BORBR
Sequence: MRLILLGPPGAGKGTQAAFLTQHYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGGLVSDDLIIGLVRDRLTQPDCANGYLFDGFPRTIPQADALKSAGIALDYVVEIEVPESDIIERMSGRRVHPASGRSYHVRFNPPKAEGVDDVTGEPLVQRDDDREETVRHRLNVYQNQTRPLVDYYSSWAQSDAAAAPKYRKISGVGSVDEIKSRLSQALQS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.