PharMolix/UniProtQA huggingface dataset:
Protein: Y545_STRP7
Sequence: MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINSVFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGTLLLLAYAGTQTRAGSLKKD
What are the official names of this protein?
UPF0397 protein SP70585_0545.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALN_LITCT
Sequence: MALKSKPGIMNITPGSKISVIRSKRVIQANTISSCDIIISDGKISSVLAWGKHVTSGAKLLDVGDLVVMAGIIDPHVHVNEPGRTDWEGYRTATLAAAAGGITAIVDMPLNSLPPTTSVTNFHTKLQAAKRQCYVDVAFWGGVIPDNQVELIPMLQAGVAGFKCFLINSGVPEFPHVSVTDLHTAMSELQGTNSVLLFHAELEIAKPAPEIGDSTLYQTFLDSRPDDMEIAAVQLVADLCQQYKVRCHIVHLSSAQSLTIIRKAKEAGAPLTVETTHHYLSLSSEHIPPGATYFKCCPPVRGHRNKEALWNALLQGHIDMVVSDHSPCTPDLKLLKEGDYMKAWGGISSLQFGLPLFWTSARTRGFSLTDVSQLLSSNTAKLCGLGIVKEPLKWVMMLIWSSGILTKSFRCKKMIFITRISSPHIWDSFFKEKSWLLLFEGLLFISKGSMLPNQLENLFLYTLWSLVKPVHPVHPIIRKNLPHI
What are the official names of this protein?
Allantoinase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AROD_SHIF8
Sequence: MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLVGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: STIMA_RAT
Sequence: MQGPGGNVSRGLPGGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV
What is the function of this protein?
Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER.  SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores.  Acts by interacting with STIM1, promoting STIM1 conformational switch.  Involved in STIM1 relocalization to ER-PM junctions.  Contributes to the maintenance and reorganization of store-dependent ER-PM junctions.
What are the official names of this protein?
Store-operated calcium entry regulator STIMATE, STIM-activating enhancer encoded by TMEM110, Transmembrane protein 110.
What is the protein family that this protein belongs to?
Belongs to the STIMATE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with STIM1 at ER- plasma membrane (ER-PM) junctions, also called cortical endoplasmic reticulum (ER), in store-depleted calcium cells. May translocate to ER- PM junctions in a STIM1-dependent manner in store-depleted cells.
Protein: MABA_MYCTU
Sequence: MTATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis (PubMed:11932442).  Catalyzes the NADPH-dependent reduction of beta-ketoacyl derivatives, the second step of the FAS-II elongation cycle (PubMed:9802011, PubMed:11932442, PubMed:17059223, PubMed:18155153, PubMed:19685079).  May preferentially metabolize long-chain substrates (C8-C20) (PubMed:11932442).  Can use CoA derivatives as substrates in vitro (PubMed:9802011, PubMed:11932442, PubMed:17059223, PubMed:18155153).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase MabA, 3-ketoacyl reductase, 3-ketoacyl-acyl carrier protein reductase, Acetoacetyl-CoA reductase, Beta-ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase, Mycolic acid biosynthesis A.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RABK1_DICDI
Sequence: MDNKRKLLKIITIGDRMVGKLSIIKNYMGRPFFQWGNSIPFDFHFKEIIIDNETVSLQLWNTHGSAYEDSKIYYRDVDCCVVCFNIHNEQSFNNLIYWIKELEANTLVDEKVPFVLIGTKSDIERTEKSISKERIEQWCKQIEDQGIVKEKIHYFETSAKLSTNIIEAYETIVKIALNQYKNKQKNSINISIEPEKPKGIFQIMIFMGVVFYF
What are the official names of this protein?
Ras-related protein RabK1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: VA0D2_HUMAN
Sequence: MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANHTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIELLRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  Regulator of osteoclast fusion and bone formation (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 2, V-ATPase subunit d 2, Vacuolar proton pump subunit d 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: COAE_PASMU
Sequence: MTYIVGLTGGIGSGKSTIAHLFMALGVPVIDADVVARDIVTKGSELLSKIVDYFGEHILCENGELNRAKLRERIFRHPEDKVWLNQLLHPAIREEMLRQLQIQTYPYVLWVVPLLIENNLTAFCQRVLVVDVEPETQIQRAMQRDNNSIELIQHIMASQVDRQTRLQFADDVIQNDADLKGNLPVLKQKVLELHHQYLQLANAQNA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_HTL1C
Sequence: MPKTRRRPRRSQRKRPPTPWPTSQGLDRVFFSDTQSTCLETVYKATGAPSLGDYVRPAYIVTPYWPPVQSIRSPGTPSMDALSAQLYSSLSLDSPPSPPREPLRPLRSLPRQSLIQPPTFHPPSSRPCANTPPSEMDTWNPPLGSTSQPCLFQTPDSGPKTCTPSGEAPLSACTSTSFPPPSPGPSCPM
What is the function of this protein?
Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells.  These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR).  This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rex itself is translated from a fully spliced mRNA that probably readily exits the nucleus.  Rex's nuclear localization signal (NLS) binds directly to KPNB1/importin beta-1 without previous binding to KPNA1/importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rex to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rex from KPNB1 and allows Rex's binding to the RRE in viral pre-mRNAs.  Rex multimerizes on the RRE via cooperative assembly.  This multimerization is critical for its full biological activity, since it may shield the viral RNA from being spliced or down-regulated, and probably exposes Rex's nuclear export signal (NES) to the surface.  Rex can then form a complex with XPO1/CRM1, RANBP3 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rex/RRE/XPO1/RANBP3/RAN complex, so that Rex can return to the nucleus for a subsequent round of export (By similarity).
What are the official names of this protein?
Protein Rex, Rev homolog, Rex-1, p27Rex.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Rex protein family.
What are the subcellular locations of this protein?
[Isoform Rex]: Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm. SUBCELLULAR LOCATION: [Isoform p21Rex]: Host cytoplasm.
Protein: RPOC1_CUCSA
Sequence: MIDRYKHQQLRIGLVSPQQISAWANKTLPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDKKEDSKFCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPIAKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLRLIIDYSLVEWKELGEEGPAGNEWEDRKVGRRKDFLVRRMELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLIDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFLIRGLIRQHFASNIGVAKSKIREKEPIVWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSSAIGDPISVPTQDMLIGLYVLTSGNRRGICANRYNPSNRKNHKNEKIYNNNYKYTKEPFFCNSYDAIGAYRQKRINLDSPLWLRWRLDQRVIASREAPIEVHYESLGTHHEIYGYYLIVKSIKKEILCIYIRTTVGHISLYREIEEAIQGFCRACSYGT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYA_BRUSU
Sequence: MAGVNEIRSTFLDYFRKNGHEVVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEHRSYNRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEDAISFAWNLITREFGLPKDKLLVTVYHTDDDAANFWKKIAGLSDDRIIRIPTSDNFWAMGDTGPCGPCSEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNLVFMQFEQQTPELRIDLPRPSIDTGMGLERIAAVLQGVHDNYDIDLFKALIRASEEATGVKAEGDFRASHRVIADHLRASSFLIADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKEPLMWRLLPALIREMGQAYPELIRAESLISETLKLEETRFRKTLERGLGLLSDASENLAEGDRLDGETAFKLYDTYGFPLDLTQDALRQRGIAVDTEGFNVAMERQKAEARANWTGSGEAATETIWFGIKDKVGATEFLGYETESAEGVIASLVRDGVEVPSVREGETISVVVNQTPFYGESGGQQGDTGTISGEGFVIAVKDTQKKGEGVFVHIGEVTEGTAKAGDVVELKVDSARRTRIRSNHSATHLLHEALRETLGTHVAQKGSLVAPDRLRFDFSHPKPISAEELEAVENLANEIILQNAPVTTRLMAVDDAIAEGAMALFGEKYGDEVRVVSMGTAKHGSKAGKAYSVELCGGTHVRQTGDIGLVRIISEGGVAAGVRRLEALTGEAARLYLEEQDERVKAIASALKTTSADVLDRVNALIDERKKLERELADARKKLALGGGSSDGGSAVEAVNGVNFLGKIVTGVSPRDLKPLADEGKKQVGSGVVLFIGVGEDGKASAVAAVTEDMVGRFSAVDLVRAASAALGGAGGGGRPDMAQAGGPDGAKAADAIAAVKALIA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT21C_HUMAN
Sequence: MDVCLSSAQQPGRRGEGLSSPGGWLEAEKKGAPQKDSTGGVLEESNKIEPSLHSLQKFVPTDYASYTQEHYRFAGKEIVIQESIESYGAVVWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPGTVLLWANKFRFSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKWD
What is the function of this protein?
Protein-lysine methyltransferase.
What are the official names of this protein?
Protein-lysine methyltransferase METTL21C, Methyltransferase-like protein 21C.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GMHA_PSYIN
Sequence: MNLSIIKAELLEAEKVLQAFLADEQNLKNIEKAASLLADSFKNDGKVLSCGNGGSHCDAMHFAEELTGRYREHRPAYPAIAISDPSHISCVGNDYGYDAIFARYLEGVGRKGDVLFCLSTSGNSKNILNAIEVAKAKGISVIALTGKDGGKMSGLADVEIRVPHFGFADRIQEVHIKIIHILIYLIEKKMA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_WIGBR
Sequence: MLINSPYIVAMTGGIGSGKSTIAKIFSELKVPIIESDIISKKIMFSEKSILNSIKNKLGINFSLNNNKYSKLVLRECIFESKSSVLFINKILHPVVKKKIKKIISNVNFPYIIWVTSLLIEENLYKYVNRILVIDVDPEIQIKRSILRDNVSKNQILNIINFQISREKRLTFAHDIINNYDYSCIRRKVFELHKYYLFKSKKYFKYDM
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAM4_PANTR
Sequence: MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTALNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVCKAMEAVAAQGKAKK
What are the official names of this protein?
Probable phosphoglycerate mutase 4.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ANMK_PHEZH
Sequence: MRVLGFMTGTSLDAVDMAVLETDGEGISAFGPAGERKLTDATREILLEATEAALKWERGEPEPQIFAKAAVTVAEEHFAAAEAFLAEHGLVWSEFDLLGMHGQTVLHERPQDGVPGRTVQLGDAGLLASLTGRPVAHDFRSADVAAGGEGAPLAPIYHLARARASGLEPPLAVLNVGGVANVTFWSGPGDFAAFDTGPGNGMIDLLVQARKAGRYDAGGRYASVGRVDEAVVRALLAHPYFEAPAPKSLDRYDFSLEPLEPLQLEDACATLVAFTAEAVGRGFELMGEVPREVVVTGGGRHNPEIMKALAARLPAPVKTAEDHGWRGDSIEAEAFAYLAARCARGQPISFPKTTGVARPMTGGRIVQPE
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: AQP8_BOTFB
Sequence: MALRSPARDYLVSMIGELVGTFLFLFFAFAAAQTANQPNGTKPLTPNATDTSKLLYIALAFGASLAANVWVFFRVSGGQFNPAVTLALVLIRAVSPTKALILIPAQLVGGSLAAAAVKGIIPGDDILFAVSLGPGVANVQGLFIELLLTFMLVFTILMLVAEKTKSTFVAPIGIGFSLFIGHLVGIFWTGAGINPARAFSPALIQASFPSYHWIYWLGPALGSFLAAGLYLGLKEMKYELVGGDADKEKREEGLTVQQADLIIETLRGLPRAIQGSGALGQFEGTTEGHRSPVDLERGAEVRILEDDPHIRKSRYGSPDSTDLPT
What is the function of this protein?
Plasma membrane water channel that regulates the reactive oxygen species (ROS)-signaling pathway through its capacity to act as a membrane channel for hydrogen peroxide uptake (PubMed:26527167).  Required for the formation of infection structures and infection, especially on host leaves where it is essential for the penetration into the host (PubMed:26527167).  Regulates the expression of proteins related to redox-regulation and intracellular signal transduction and plays a role in the distribution of mitochondria in the hyphae (PubMed:26527167).
What are the official names of this protein?
Aquaporin-8.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: ABHD3_BOVIN
Sequence: MQRLAMDLRMLSRELSHYLEHQVRVGFFGSGVGFSLILGFSVAYACYYLSSIAKKPQLVTGGESFSRFLQDHCPVVTETYYPTVWCWESRGQTLLRPFITSKPLVQYRNELIKTADGGQISLDWFDNDNSKHYMDASTRPTVLLLPGLTGTSKESYILHMIHLSEELGYRYVVFNNRGVAGENLLTPRTYCCSNTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGPKTPLKAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHMFVKQIDVDHVMKAKSIREFDKRFTSVMFGYRTIDDYYTDASPNRRLKSVGIPVLCLNSVDDVFSPSHAIPIETAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRVFKQFVQAMIEHGHELSSM
What is the function of this protein?
Phospholipase that may play a role in phospholipids remodeling.  May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position.  In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2.  In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.
What are the official names of this protein?
Phospholipase ABHD3, Abhydrolase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: TGT_CHLTR
Sequence: MALRFEILHQSKKSRARVGRIETAHGYIDTPAFVPVATNGALKGVLDHSNIPLMFCNTYHLIVHPGAEAIAAMGGLHQFIGRNAPIITDSGGFQIFSLAYGSVAEEIKSCGKKKGGNTIIKVNDDGVHFKSYRDGRKLFLSPEISVQAQKDLGADIILPLDELLPFHADPTYFHQSSQRTYVWEKRSLDYHLKNPGIQSMYGVIHGGTFPDQRKLGCKFVEDLPFDGSAIGGSLGKNLQDIVEVVGVTAANLSAERPRHLLGIGDLPSIWATVGFGIDSFDSSYPTKAARHGMILTSQGPLKINNQRYSSDLNPIEPGCSCLACSQGITRAYLRHLFKVHEPNAGIWASIHNMHHMQKVMREIREGILNDRI
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KDM5_CAEBR
Sequence: MRGRRQEDIATTSSAPSTSTSHKKKTVSSNGSFRPRTQSNPGGKMEMYDHFYKNFQRPPMAPVYYPTSEEFADPIEYVAKIRPDAERYGVVKIVPPSDFKPPFAIDKEKFTFRPRTQKLNEVEAIVKEKHTFIERLVNFNRYSGLQFEFPVDRDGNVVDLYRLHRIVQNFGGCEEVNDEERWRDVAREYLPKEQMTRGVPSYFINLIRAHYNLHIEPFNRNLKEKAMKNEDESDDELEELKHKYQHHHGTMRSEPENTDGKNTEDVEEECPMSMQSGRRRSKNKKPVPAKKSSNGTPKKGSRGKKNSKTEEDEEENEDVIEQVYCVSCNEGKDEDLLLLCDIEGCNSGRHTYCCDPVLDEVPEGEWRCPKCIESEDAKIGLDWGFYDAETEYNLNTFTEFANKWKCDYFGVDNVSKVSCDALEKEFWKNVVSHDNPVAVKYGADLITSRVGSGFPRKEDKHTGPDSKLKQQYANHAWNLNNMPVLSESVLSYFNTGISGMMVPWVYVGMCFSTFCWHTEDHWTYSVNYNHFGERKIWYGVGGDDAEKFEEALKRLAPGLTGRQRDLFHHMTTAANPSLLRSLGVPIYSVHQNAGEFVITFPRAYHAGYNEGLNFAEAVNFAPIDWLAKGRECVQSYSNVRRYLVFSHDELLFKMIEAMDRLGLSTTLAAYDELKRVIEKQKRLRQFIAQLGVPARNVEQVAFEKIPDEQRSCRFCKTTLFMCALICNKHKRMTCVEHHDHLCKTCTPKDYKYQYRYEIDNLTHLFDELGKRTVDTAGWQEDDDDMYTQEEMPKLEPMVDLYNVEEQSSSRQKNQVHNIIAIQHTAKSAIEKANQLLFKKVRTRTKTRCQRADTRTDADGVKSLIEQMQGMDCNLSGLIDKLQKFLDQIDAWRSKAQIMMSQEHKYSKDDFEHFIEEGDEYDIKLSEIEELRKVVGMKEWSERAIEITSWAPTSNMEKDIDFEYKMRYTNKDVIALIREGSRSSSNHTSQLIAKLQHMLAEANKREAEATEYFDNPSLDKLQSIWKNLRTSDWFYEPYINLVRFEIGQIAKIKSMIDSTIPALSGLDLKPQLLRLGDSSITFAKAVELSKACELSKTLHKSQEHSSLLELINRMNLFTERIAKLFKPMNSYHNLFEIVSERDDLTPLAEGQVLQLYYQGETINSGNEWHQIKDFDSLEQMLHHQSSLREMQSRIFEKVKQTNSARGLEGCCCLGGNKSDSSESVLSCIMCESQFHVRCCEWSTFFQHLPKGCFMCVRCLRGQRPVIDDVANALNGTPSGCMETHLVRNLIQKSRIITQNLMDCSNKRQSGEVASDEMCKKALFDWLACEIMNPNGLPKAVELIHEFFGDYLEKQASAALELQQRPVKSKPSASLFDPKLNSKRKRPNPSQKDSSKSKSRKRQGQISPIDYCEEETEFKSCQARSCLKPFGDSVNWVMCDAGCKNWFHVICVGFTLREINDMHEYRCSSCLDHADSPASSVSTE
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.  Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.  Involved in larval development and vulva formation.
What are the official names of this protein?
Lysine-specific demethylase rbr-2, Histone demethylase rbr-2, Jumonji/ARID domain-containing protein rbr-2, [histone H3]-trimethyl-L-lysine(4) demethylase rbr-2.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPH8_ARATH
Sequence: MHSLSWFLLVIGLSVGLSSGKWNEKNSVIFTNSLGRNKVLKVNCISNDDNLGFHFLRHGQTYDFSFHDSLFKSEFYCDLWQGPNFKLHAAFTAYEGGGLIVHYGKKNFWDVRDDGIYFTHGQKMPKLEYTWK
What are the official names of this protein?
S-protein homolog 8.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTC_TALWO
Sequence: MASLEVFVLYLRIFFISFMSRARSLFSFVTSPAITAEHGKVQKLQAKPGSDRAPDSWIQYRHSKLVDPSTYNDLGLCGGLPLRVHKHAHLADKGARRAQEDWKRLVGPIRNFTGCLSPRFNGIAVAIPECIPERLEAVTYANEFAFLHDDILDTVGKEDGEEENNEMARGFESVLEPSRNVKMSVSGKSQMQAKLILELLDLDESQAMVLLKSWEGLVKGESGSQHFDFQSLDEYLPHRVVNLGQTFWFGIITFAMGLTVSNEEMELTKPITEPAYATLALANDFFSWEKEYVEFQGNPTSGNMANAVWIIMKEHSVDLEEAKVICQDKIRESCEEYRRRKREFELQSAEQVSIDAHRYLSALEFSISGNVVWSQYTERYHFHKPEHWRQVENVDDDGNKSDDSGIAMKDSPESTVVDVEDNVPSTFLNFGSSGTNIRSKKTLVSPVLETKLPEMTNQVVLAPFQYVSSLPSKKVRHHAIDALNIWFSVPEADLNMIKDAIDQLHNASLMLDDIEDNSPLRRGHPSTHMIYGISQTINSANNLFVMSLDTIRQLKSPDCLDVFISELKRLHIGQSLDLFWTSNVQCPTLEEYYKMVDYKTGGLFQMVAKLMGAKSPKSKRKVPDVSTLTTLFGRYFQIRDDYQNLMSKEYTDQKGFCEDLDEGKFSLPLIHCLTTSPNIRLQSILHQRKTMGKMSFETKKLVLDHLEETKSLEYTKEMLDCLHVRLHKELDVLEKQTGVNNFLLRLLLKRLHVK
What is the function of this protein?
Bifunctional sesterterpene synthase; part of the gene cluster that mediates the biosynthesis of the asperterpenoids, sesterterpenes that exhibit anti-tuberculosis activity (PubMed:30548032).  The first step of the pathway is performed by the sesterterpene synthase astC that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into preasperterpenoid A, respectively (PubMed:30548032).  The cytochrome P450 monooxygenase astB then dually oxidizes preasperterpenoid A to produce asperterpenoid A along with a minor product, asperterpenoid B (PubMed:30548032).  Finally, the cytochrome P450 monooxygenase astA converts asperterpenoid A into asperterpenoid C (PubMed:30548032).
What are the official names of this protein?
Bifunctional sesterterpene synthase astC, Asperterpenoid biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.