PharMolix/UniProtQA huggingface dataset:
Protein: ALNE_EMENI
Sequence: MSSDDTVKQEHSCSADSEKQDSSCASDNEQPKEPQSPRNIHGLLWVVTILAIYSSTFLFALDNTIVANIQPAIISSLNGIEKLAWSGVAFVMASSATVLTWLQIFNQFNIKWMYIFSIAVFMGGSAICGAAQSMDMLIGGRVICGIGGVGQYVGVMNFLPRLTTMQERPMYVSAMGLTWGAGTVLGPIIGGAFTDSSAGWRWSFYINLVVGGLFAPVYIFLLPSLEPQPAGTTVSSRLKRMDLVGTLILFAAFAAGVIGINFAGAMYPWSEPGIIVAITLGGVLFIVFGIQQTYCILTTEETRLFPVELVSWRQPLLSLLFVCGCCTGVCVTVPTYVIPLYFQFTEGDESLQSGVRLLPFVCLLVFSCVSGGYLAGRLGYYIPWYIMGGGFCLIGSALMYTIKPSSGPGATYGYSSLIGLGSGMYLQLGHAVAQAKVKPEKVPAAVAFTTTAQLNGLTFALVLSQCVFVNEAAKRIGWILPHEPRSTIVDAISGTGSTFVQELPTATQNEVLGAIVTAIDRTYILCIVAAAVTLLATLGMKWERLFIEAAAAA
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of asperlin, a polyketide showing anti-inflammatory, antitumor and antibiotic activities (PubMed:30339758).  Is probably involved in the efflux of asperlin (Probable).
What are the official names of this protein?
Efflux pump alnA, Asperlin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CITB_SALTY
Sequence: MKQLEKLIIEATVLTEPEAEVERVMQVCNACRYCEGFCAVFPAMTQRLEFGKADIHYLANLCHNCGACLHACQYAPPHEFAINVPKAMAQARLETYQQYAQPAAFGALYRRAGITVALALIVGLTLFLLLAMALKGSLIHPPLAGDFYQIFPHSLLAWMFGSVFVLAIGLLMAGVIRFWREISPGVPRSAEIAEASHNALTLKYLDGGHGKGCNEADDAFTLLRRRFHHFTFYGFMLCFAATVVATGYHYVAGWEAPYPFFSLPVMLGTLGGIGLLIGPAGLLWLNLRRSPLHGDARQKPMDRGFILLLFLTSLTGLALLAGRDTSGMGILLALHLGVVMALFLTLPYGKFAHGFFRCAALLKWAVEKRRGKHAGDTGN
What are the official names of this protein?
Citrate utilization protein B.
Protein: RSMH_ECO57
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTU1_SCHPO
Sequence: MSSLRLRLKYENQSAVETVEANATVGSFLDLVAAKFSLPRNSIALKFGFPPQDIPLVNSDVPLSTLVSSGQQILVLKNAATSFSTNEPAKPPIPNAATKPTFPPQTEISNPPAVSHQSKNTSQDPPYVSTPIGDIALRVMPDDNSCLFRALSKPLGFSPYELREIVANQVLSNPDIYSTAILGKPSIEYASWIRKETSWGGYIELSILSSHFGVEICSVDVKTGRVDSYNPQPATGQRTYIVYSGIHYDLAALAAVLWDTDVDVVLFDASDVTITPYVQQLASLLKNMHYYTDTASFSIRCTICGTGLVGEKDATAHALATGHTQFGEY
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (By similarity).  Has a role in meiosis.
What are the official names of this protein?
Putative ubiquitin thioesterase otu1, Meiotically up-regulated gene 141 protein, OTU domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PMPB_CHLTR
Sequence: MSSMKWLSATAVFAAVLPSVSGFCFPEPKELNFSRVGTSSSTTFTETVGEAGAEYIVSGNASFTKFTNIPTTDTTTPTNSNSSSSNGETASVSEDSDSTTTTPDPKGGGAFYNAHSGVLSFMTRSGTEGSLTLSEIKITGEGGAIFSQGELLFTDLTGLTIQNNLSQLSGGAIFGESTISLSGITKATFSSNSAEVPAPVKKPTEPKAQTASETSGSSSSSGNDSVSSPSSSRAEPAAANLQSHFICATATPAAQTDTETSTPSHKPGSGGAIYAKGDLTIADSQEVLFSINKATKDGGAIFAEKDVSFENITSLKVQTNGAEEKGGAIYAKGDLSIQSSKQSLFNSNYSKQGGGALYVEGDINFQDLEEIRIKYNKAGTFETKKITLPKAQASAGNADAWASSSPQSGSGATTVSNSGDSSSGSDSDTSETVPATAKGGGLYTDKNLSITNITGIIEIANNKATDVGGGAYVKGTLTCENSHRLQFLKNSSDKQGGGIYGEDNITLSNLTGKTLFQENTAKEEGGGLFIKGTDKALTMTGLDSFCLINNTSEKHGGGAFVTKEISQTYTSDVETIPGITPVHGETVITGNKSTGGNGGGVCTKRLALSNLQSISISGNSAAENGGGAHTCPDSFPTADTAEQPAAASAATSTPESAPVVSTALSTPSSSTVSSLTLLAASSQASPATSNKETQDPNADTDLLIDYVVDTTISKNTAKKGGGIYAKKAKMSRIDQLNISENSATEIGGGICCKESLELDALVSLSVTENLVGKEGGGLHAKTVNISNLKSGFSFSNNKANSSSTGVATTASAPAAAAASLQAAAAAVPSSPATPTYSGVVGGAIYGEKVTFSQCSGTCQFSGNQAIDNNPSQSSLNVQGGAIYAKTSLSIGSSDAGTSYIFSGNSVSTGKSQTTGQIAGGAIYSPTVTLNCPATFSNNTASMATPKTSSEDGSSGNSIKDTIGGAIAGTAITLSGVSRFSGNTADLGAAIGTLANANTPSATSGSQNSITEKITLENGSFIFERNQANKRGAIYSPSVSIKGNNITFNQNTSTHDGSAIYFTKDATIESLGSVLFTGNNVTATQASSATSGQNTNTANYGAAIFGDPGTTQSSQTDAILTLLASSGNITFSNNSLQNNQGDTPASKFCSIAGYVKLSLQAAKGKTISFFDCVHTSTKKIGSTQNVYETLDINKEENSNPYTGTIVFSSELHENKSYIPQNAILHNGTLVLKEKTELHVVSFEQKEGSKLIMKPGAVLSNQNIANGALVINGLTIDLSSMGTPQAGEIFSPPELRIVATTSSASGGSGVSSSIPTNPKRISAAAPSGSAATTPTMSENKVFLTGDLTLIDPNGNFYQNPMLGSDLDVPLIKLPTNTSDVQVYDLTLSGDLFPQKGYMGTWTLDSNPQTGKLQARWTFDTYRRWVYIPRDNHFYANSILGSQNSMIVVKQGLINNMLNNARFDDIAYNNFWVSGVGTFLAQQGTPLSEEFSYYSRGTSVAIDAKPRQDFILGAAFSKMVGKTKAIKKMHNYFHKGSEYSYQASVYGGKFLYFLLNKQHGWALPFLIQGVVSYGHIKHDTTTLYPSIHERNKGDWEDLGWLADLRISMDLKEPSKDSSKRITVYGELEYSSIRQKQFTEIDYDPRHFDDCAYRNLSLPVGCAVEGAIMNCNILMYNKLALAYMPSIYRNNPVCKYRVLSSNEAGQVICGVPTRTSARAEYSTQLYLGPFWTLYGNYTIDVGMYTLSQMTSCGARMIF
What are the official names of this protein?
Probable outer membrane protein PmpB, Polymorphic membrane protein B.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: RL14_RHORT
Sequence: MIQMQTRLDVADNSGARQVQCIKVLGGSKRMIAGVGDIIVVSVKEAIPRGRVKKGDVHRAVIVRTAKEIRRPDGTSIRFDRNAAVLLNKQNEPIGTRIFGPVVRELRARKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CCL20_RAT
Sequence: MACKHLPFLALAGVLLAYLCSQSEAASNFDCCLTYTKNVYHHARNFVGFTTQMADEACDINAIIFHLKSKRSVCADPKQIWVKRILHLLSLRTKKM
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR6.  Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions.  The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and autoimmune diseases.  CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes.  Involved in the recruitment of both the pro-inflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation.  Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells.  Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility.  May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells.
What are the official names of this protein?
C-C motif chemokine 20, Beta-chemokine exodus-1, CC chemokine LARC, CC chemokine ST38, Liver and activation-regulated chemokine, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Small-inducible cytokine A20.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_BEUC1
Sequence: MAELFYDDDADLSVIQRKKVAVIGYGSQGHAHALNLRDSGVDVRVGLREGSASRAKAENEGLKVLTVPEAVKEADVVVILAPDQHQRGLYTADIEPNLNPGTTLVFGHGFNIRYGYIKPSADLDVVMVAPKGPGHLVRREYVDGRGVPVIVAVEQDATGGAWELALSYAKAIGGLRAAGIKTTFTEETETDLFGEQAVLCGGVSQLVQYGFETLTEAGYQPEVAYFEVLHELKLIVDLMYEGGIAKQRWSVSDTAEYGDYVSGPRVIDPRVKENMQAVLADVQNGAFAARFIADQDAGAPEFAELRAKGEAHPIEGVGRELRKLFAWVKPSDSDYTEGSAAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PNP_FRAT1
Sequence: MKIFREVFELGNKEIILETGGMARQADGSVTVSCGNNVVLVTTVVKKSVADGTDFFPLSVHYLEKTYAAGKIPGGFLRREGRPSEEQILISRLIDRSIRPSFPDGFFNEIQIVATVLSYDGAFSPDILALIGASASLAISGAPYDDVVAGVRVGYTNGKYILNPNKQDLRDSDLDLVVSGTDDAILMVESEANSLPESVMLGGILYAHKHLKTIINSINRLAKVASKPRIEYSIYQINKFLKSQIKSQFFGEIKNAYTIASKQERNLKLNAIRKNVLEYIFSSDVDGNEYTEKEILEAFHDIEKDLVRSNILEGKPRIDGRCTETIRPINVKIGVLPGVHGSALFTRGETQALVVTTLGSDRDAQLVESLDGIEKCRYMLHYNFPPYSVGECGMVGMAPKRREIGHANLAKRATQAVFPNEEAYPYVVRVVSEILESNGSSSMATVCGSSLSMMDAGVPIAEPVAGIAMGLIKDGAKYAVLSDILGDEDHLGDMDFKVAGTRYGVTALQMDIKIKGISREILEQALEQARAGRLHILGIMNEVIKEHKEAVSDVAPQIHVMNINPAKIKDVVGRGGATVKGIVEKTGAQIDTSDSGEVKVFAKDKKSMDMAVAMIEEIVAEVEEGQVYKGKIVKLLDSGVFVNLLGSQDGYLPFSEIEQAGMKTNSLVEGQGLEVLVQNIDRGGRVKLSLVAR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_PHOPR
Sequence: MYMLSSDERARLKWACRRGMLELDVIIMPFFEECLDDLPDQEQRDFVSLLTSDDPDLFTWMMGHGRSENPAHAAMVDKIVAHNNSKLR
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_SOYBN
Sequence: MNVLLCSINTLKRLYDISAVEVGQHFYWQIGSFQVHAQVLITSWVVIALLLVSAILIIRNLQTIPAFGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSIAYFYAGLSKKGLAYFNKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NCB5R_ASHGO
Sequence: MDYKFEALVTALVLAVSFIFIYGKFSGAKQSQPAVKTTLNKDWQEFSLLTKTVLTHNTAIYRFGLPEADAVLGLPIGQHISISGVIDGKEMLRSYTPTSLDSDATGYFELLVKSYEKGNISKMLAELAIGDRIKVRGPKGFYHYEPNMYKEIGMIAGGTGISPMYQIIRAIFSNPRDKTRVCLVYGNQTKDDILLKPELDAMVAAKPDQFKILYMLDKVAEGEQWEGKLGYITEAIMREHLPAPSSSAQLLLCGPPPMVSSAKRIAVSLGFEKAKPISKKGDQVFAF
What is the function of this protein?
NADH-dependent reductase for DPH3 and cytochrome b5.  Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.  By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, Microsomal cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: HEM3_SYNR3
Sequence: MTASSLRIASRRSQLAMVQTEWVRDELANAHPGLEISIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLVNRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVMHAKNKDLTLATLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVITRLEKLDSGQFDCLILAAAGLGRLGLGDRIHELIDPSISLHAVGQGALGIECRDGDAAVLEQIKVLEHRPTSLRCLAERAFLRTLEGGCQVPIGVNTRFEGDELVLTGMVASLDGKQLIRDELRAPQDQAEDLGNRLAELLRSQGAGEILAKIFAEARPEA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YIGG_ECOLI
Sequence: MLRIFIPTSNGKISRRRYIFSFILINFIFAFLIIFFNDGEAGFLVIVSTIVLHYLVINMNCQRLRDSGFIYIKTYVFGTLAVYIISIITMIAEDFACSGNGSMIFLICYFSTFSMLMLAPTDSSKQ
What are the official names of this protein?
Inner membrane protein YigG.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IOVO_EUDEL
Sequence: VSIDCSGYPKPACTLEFFPLCGSDNQTYSNKCAFCNAAVEKNVTLNHIGEC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS2_STRP8
Sequence: MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTNSERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDLVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: ODO1_LEPIC
Sequence: MKIEKLMALYGENGALLEELYNQYKLNPETLDKEWKSFFQEVDTNGLANGSGYTNGNGKSAVATSFTDAQAASIREMGIINLLNAYRRQGHLAAKLDPLGIQKPNRTFIDSKLHNISPADIDTVVDSETLGRVKLAEIVDLYEKVYCNTIGAEHFYLVNDEEREWLQKKMESPEFLAPLPRGIKLRLFEKLFQADYFETFLAKKYVGKKRFSLEGGESFIPLLDTIVEEAGYHQMDGLVIGMAHRGRLNVLVNIIEKPASLIFAEFEEKTDKDNLSYADVKYHLGYSNSRMTTSGKEVKLSLAFNPSHLECVDPVVTGSVRARQTLIGDKDRSKYMPILIHGDAAFAGQGVVAETLNLMNLEGYTTGGTFHIVVNNQIGFTTLPDESRSTLYATDLAKGFQIPIIHVNGDDPEAVYRVVKLGMEYRQKFKKDFIIDLVCYRRLGHNETDEPAFTQPKMYAIIKNHPPTVKLYEKRLVEEGDIPQEDIDFIKNGSMHGLEDSFQRAKEQDVKIRVDTMQGVWSKFSKDSLDSEPATKLLAEQMHGIVQALTSVPQGFTPNSKLVKLLQSRKEMAEGKIPVDWGFAEALSFGSILESGFRIRLSGQDSQRGTFSHRHAVLVDTNTNEKYIPLNHISSKQAKAEIINSSLSEFSVLGFEYGYSLSDPNALVMWEAQFGDFANSAQVIFDQFISSSEVKWQRLSGLIMLLPHGYEGQGPEHSSARLERFLQLCALDNMQVCNLTTAAQYFHLLRRQMLRNYRKPLVIVTPKSLLRFPASLSPVEDILQGAFREILIDDSGSKPDKIEKVVFSAGKVYYDLMKYKDENKIKNVALVRVEQIYPFPAKEIQSSLKTFKNAKQFVWCQEEPKNQGAWFFVRERIEELLPGNARLVYAGRHESPSPAAGHMKLHLQEQDQLVLDAFQA
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: Y260_STRPQ
Sequence: MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFRENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYAALNGFTLSFIIVAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIGSGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLFISLLRIFGRND
What are the official names of this protein?
Uncharacterized membrane protein SPs1599.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PFKA_BUCAI
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRTALSERLEVFGIYDGYLGLYENRMVQLDRYSVSDMINRGGTFLGSARFASFYQDKIRSIAVQNIKKRKIDALVVIGGDGSYIGAQKLTEMGIPCISIPGTIDNDVSGTDYTIGYFTALQTVVEAIDRLRDTSSSHQRISIVEVMGRHCGDLTLAAAIAGGCEFIVLPEIDYKKEDLVIEIQAGIAKGKKHAIVAITEYICDVEELAQYIEKKTNRETRATILGHIQRGGAPVVYDRILASRMGAYSVELLIKGYQGKCVGIQNEKMVFNDIKNALKNMKRTFKKDWLITAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL2_HPV65
Sequence: MQASRRTKRDSIPNLYAKCQLSGNCLPDVKNKVEADTLADRLLRWLGSVIYLGGLGIGTGRGSGGSSGYNPLGAPSRVTPSGTVIRPTVPVEGLGPSEIIPVDVVNPGSSSVVPLEDLTVPEVTIDSGEVGGGGLHPSEIDVVTSSDPISDVTGTSSHPTIISGEDNAIAVLDVSPTEPPTKRIALGTRGATSTPHISVISGTTEFGQSSDLNVFVNATFSGDSIGYTEEIPLEELNTIQQFEIETPPKTSTPRETIGRALERARDLYNRRVQQIATRNPAMLGQPSRAIVFGFENPAFDADITQVFERDLEQVAAAPDADFADIVRIGRPRFSQTDTGQIRISRLGRRGTIKTRSGLQIGQAVHFYYDLSTIDTADAIELSTLGQHSGEQSIVDAMIESSFVDPFETPDPTYTEEQQLLDPLTEDFSNSHLVLTSSRRGSSFSIPTIPPGLGLRIYVDDVGSDLFVSYPETRVIPAGGLPTEPFTPLEPPFFSEFYSSDFVYRPSLYRKKRKRSDIF
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: YDHX_ECO57
Sequence: MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHAPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
What are the official names of this protein?
Uncharacterized ferredoxin-like protein YdhX.
Protein: SURE_CLOK5
Sequence: MRLLLTNDDGIMAEGIQVLAKHFEKDNEVIIAAPDVQRSGSGHCITTVPGELIIQEVKLEGINSKAYSITGTPADCARLGVRKLGNNQIDMVISGINNGFNLGIDSLYSGTVSAAIEAAICETPSIAVSLDTKGGNYDYNIAAEYALEVFSIYKDKYKNKDENVVLSLNVPCLPREKIKGLKVCRVGFKYHLQEIYDKGEKTEELSYNYTDIYYVKRGYAALSPLHYDLTNYKILGDINNLFTEK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_PSEA8
Sequence: MWFRNLLVYRLTQDLQLDADSLEKALGEKPARPCASQELTTYGFTAPFGKGPDAPLVHVSQDFFLISARKEERILPGSVVRDALKEKVDEIEAQQMRKVYKKERDQLKDEIVQTLLPRAFIRRSSTFAAIAPSLGLILVDSASAKKAEDLLSTLREALGSLPVRPLSVKVAPTATLTDWVKTQEAAGDFHVLDECELRDTHEDGGVVRCKRQDLTSEEIQLHLTAGKLVTQLSLAWSDKLSFVLDDKLAVKRLRFEDLLQEQAEKDGGEDALGQLDASFTLMMLTFAEFLPALFEALGGEEIPQGV
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS8_GLUOX
Sequence: MSLSDPLGDMLTRIRNAQRARHAVCVAPASKLRASVLEALKREGYIRGFAAEELRKGVAQLRIELKYVEGQPVIKEIHRVSKPGRRVYSKIKELPRVYAGLGVSILSTPRGVLSDVEARAANVGGEVLCRVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CPT4_SOLLC
Sequence: MAFSLQLQQIFVSYTRFCSQPKSITNPLISLKLPSIHPLAFAQNAAVSNIDTGVAAIDGSAEEVSLPPQLRRELMPKHVALIMDGNRRWAKMRGLPVALGYEAGIRAVRKIIELCGNWGIMVLTLFAFSSDNWLRPKVEVDILMSLFERALNDELENFAREGIRISIIGDSSKLPKSLQDLIAKAVKTTKENSRLHLVVAVNYSGQHDVVQACQTIAQKVKDDIIETKDINSFLIEQELQTNCIDFPCPDLLIRTSGELRLSNFLLWQLAYSELFFSHSHWPDFGEAEFLEALCSFQQRQRRYGRQSS
What is the function of this protein?
Uses neryl diphosphate and geranyl diphosphate to catalyze the cis-prenyl chain elongation and produce polyprenyl diphosphate with a chain of 55 carbons.
What are the official names of this protein?
Cis-prenyltransferase 4, chloroplastic, SlCPT4.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=Localizes in punctuate patterns inside the chloroplasts.