PharMolix/UniProtQA huggingface dataset:
Protein: EFG_STAAB
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAAPIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN143_RAT
Sequence: MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQPDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSEGVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHAASSEMGHQPHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD
What is the function of this protein?
Transcriptional activator.  Activates the gene for selenocysteine tRNA (tRNAsec).  Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters.  Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8 (By similarity).
What are the official names of this protein?
Zinc finger protein 143, Zfp-143, Selenocysteine tRNA gene transcription-activating factor.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADC_CLOBB
Sequence: MLKSEVSKQITTPLTAPAFPRGPYRFHNREYFNIIYRTDADALRKIVPEPLELGEDPLVRFEMMAMPDTSGLGSYTECGQAIPVSYNGKKGDYLHMMYLDNQPAIAVGRELSAYPKKLGYPKLFVDSDTLVGTLDYGKLRVAIATMGYKHKQLDLNEAKEQICRPNFMLKIIPNYDGTPRICELISAQIKDITVHEAWTGPARLQLFDHAMAPFNDLPVKEIVSSSHILTDLTLPSPEVIYDYLKK
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: RL4_HALS3
Sequence: MQVTVRDLDGDDAGTLDLPRVFEEPVRPDLVKRAVLAAQANRTQEYGADEYAGLRTTAESQGSGRGMAHVPKANGQGARVPQTVGGRKAHPPKAEKDHGLDVNDKERKAAVRAAVAATTDSELVADRGHNFDDDVEFPLVVSDDFEDLVKTQDVVSLLEALGVHADIERADEGRTVRAGQGTLRGRKYQEPTSILFVTASESGPSTAARNLAGVDVATGREVNAEDLAPGAEPGRLTVWTESAVEEVAQR
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RUVB_NITWN
Sequence: MTEASRIVAPERHADDVGDTALRPQKLSEFIGQRQARANLQIFIDAARKREEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEVLYPAMEDFQLDLIIGEGPAARSVKIELAKFTLVGATTRAGLLTNPLRDRFGIPVRLNFYTEDELEKIVSRGARVLNVGMTPDGANEIARRARGTPRIAGRLLRRVRDFAEAADAAAIDRAVADHALGALEVDAAGLDAMDRRYLTTIALSYGGGPVGVETMAAALSEPRDAIEDIIEPYLIQCGYLQRTPRGRLLTSHAFRHLGLTEPSRDPAQSGLFGQDEDR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RIMM_PSE14
Sequence: MNATPASADDLIVIGKIYSVHGVRGEVKVFSFTDPIGNLLDYKTWTLRREGSVEKQVELVSGRLQSKFLVAKLKGLDDREEARLLSGYEICVPRNLFPDLDDGEYYWYQLEGLKVIDQLGQLLGKIDHLLETGSNDVMVVKPCAGSLDDRERLLPYTEQCVLAIDMAAGEMKVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_SYNPW
Sequence: MASPAFHPLDCPDPAQVSFGTDGLRGHVGSAITSTLALQVGFWCGRVLPADGPVLIGMDSRTSGSMLVSALAAGLTAAGREVWTLGLCPTPAVPGLIRRFGAAGGLMVSASHNPPEDNGIKVFGADGSKLGSALQSRIEAGLRGEEPASAQAHAFGASHQRSDLLDLYKQDLLSSVRHQRLDGVPIVLDLCWGSATACGAAVFSELGADVTVLHGEADGERINVDCGSTHLEPLRRAVLERGAAMGFAFDGDADRMLAVDGRGRIVDGDHVLFLWGSALQDSGVLPDQRLVATVMSNLGFERAWQARGGQLDRTPVGDQHVHAAMVRSGAALGGEQSGHILSSAHGLSGDGVLTALQLASLCHGQGITLADWLDRSFEAYPQKLVNVRVPDRSRRKAWADCQSLTALVQEAERSMAGDGRVLVRASGTEPLLRVMVEAADPKAVEHWTQRLAEAADQHLNAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DNAA_TREDE
Sequence: MSEWDYKIFWDEAVNQFKEELAFSIFSMWFLPSKYEKSTENTVYLSVPSKFFRDQMIHNYKNGIEKKLFELSGKKISIDFIIKPNTSEDLSKAENEGGNDKKEDAAKPSSAESKKKSVKTEGGRGQHPDLRPEYNFEDFVVGPNNNFGVNAAIAVSTNPGSAYNPFLIYGGVGLGKTHLMQAIGNKIWDTTKLKVIYVTAENFTNEFVECVQKKMMPAFKSKYRKADVLLIDDIHFFQGKVETQEELFHTFNELYEKNKQIVFTCDRPPAELKNLSQRLKSRFERGLNVDLQTPAYEIRYAILLKKMEKHSTKIPNEFIDMVAKNVSSNVRDLEAALTKLIAYTELTKKTMDEATAKNLLRDIFGSTRQRNVTIDLIQRTVADYFSISISDIKSKKRTKSFSFPRQIAMFLCREMTECSTTELGNDFGGRDHTTILHGCNKIEEQIAADPSLEKIIHELRNTIKENTNK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_PUCGR
Sequence: MGKEKNHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAAGTGEFEAGISKDGQTREHALLAFTLGVRQLIVAINKMDTTKWSEQRFEIVKETSNFVKKVGYNPKSIAFVPISGWHGDNMLEESTNMGWFKGWTKETKAGVSKGKTLLDAIDAIEPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGTIKAGMVVTFAPANVTTEVKSVEMHHEQLEAGMPGDNVGFNVKNVSVKDIRRGNVCGDTKCDPPKEAASFVAQVIVLNHPGQIGNGYCPVLDCHTAHIACKFDTLQQKIDRRTGKALEEAPKFVKSGDACLVKMVPSKAMCVEPFADYPPLGRFAVRDMRQTVAVGVIKSVEKTDGKAGKVTKAAVKPVPRSSYAR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CAMC1
Sequence: MGYKHKDLIGTRELSKEEILYFLEAAKEFKELNLSQVKKNDYLRGKTTINAFYENSTRTRTSFEIAAKRLGADTINFSSSNSSVTKGESLNDTMNNMAAMRTDIIVLRHPSSGAAKFAADRTEASVVNAGDGTNEHPSQALLDLFTLREHGKILDKNLNVAIIGDIARSRVARSDIWAMKKFGINLKLFAPRMMMPKDAEVFESQICKNMEEACEGSDVIIMLRIQLERGGADVAFPSSREYSKFFGLNKNRIKLAKPDAIVLHPGPINRGVELNSDVADGTHSVILNQVENGVAIRMAILNTLAKNRG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SYNE4_HUMAN
Sequence: MALSLPLGPRLGSEPLNHPPGAPREADIVGCTVCPASGEESTSPEQAQTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPSSYEDPAGGKHCEHPISGLEVLEAEQNSLHLCLLGLGRRLQDLEQGLGHWALAQSGMVQLQALQVDLRGAAERVEALLAFGEGLAQRSEPRAWAALEQILRALGAYRDSIFRRLWQLQAQLVSYSLVFEEANTLDQDLEVEGDSDWPGPGGVWGPWAPSSLPTSTELEWDPAGDIGGLGPLGQKTARTLGVPCELCGQRGPQGRGQGLEEADTSHSRQDMLESGLGHQKRLARHQRHSLLRKPQDKKRQASPHLQDVRLEGNPGAPDPASRQPLTFLLILFLLFLLLVGAMFLLPASGGPCCSHARIPRTPYLVLSYVNGLPPV
What is the function of this protein?
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton.  The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity).  Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope.  Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).
What are the official names of this protein?
Nesprin-4, KASH domain-containing protein 4, KASH4, Nuclear envelope spectrin repeat protein 4.
What is the protein family that this protein belongs to?
Belongs to the nesprin family.
What are the subcellular locations of this protein?
Nucleus outer membrane; Single-pass type IV membrane protein. Note=Localization at the nucleus outer membrane requires the presence of SUN1.
Protein: CLPX_GLOVI
Sequence: MPKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVELCNEILDEELFEGATQPQPQPTKVKASRSSRRDTSLKKIPKPQEIKSYLDQHVIGQQEAKKILSVAVYNHYKRLSSKLEESGDEVEIQKSNILLIGPTGCGKTLLAQTLADLLDVPFAIADATTLTEAGYVGEDVENILLRLLQVADGEVERAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQEYIQIDTANILFVCGGAFVGLERVVEQRIGKRAMGFVQAGEPQKREQRLVESLKALEPDDLVKFGLIPEFIGRIPMVAVLEPLDEEALIEILTEPKNALLKQYQRLLRMDGVEMVFEPDAIKTIAQEAFRRKTGARALRGIVEELMLEVMYEVPSRADIRKCVITREMVEKRSTSELLILPSSLPKPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: Y1165_METM6
Sequence: MGNYHVTLQASYIAKNVEDVEDAIGVAISQIGKLLNKGSLDYVDIDVGLTICPKCGEPIDCVLVVAKTAIVGILLSMKVFNAESPEHAVRIAKSSIGRALKDIPLEDVDVVEI
What are the official names of this protein?
UPF0212 protein MmarC6_1165.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: CHARK_ORYSJ
Sequence: MALLLWVFSCSLFSLWILSFMRSQATEARHGTLAVMCDERARILQDQVKVSMNHLQALAILVSTFHHSKSPSAIDQTTFARYVERTAFERPLTSGLAYAARVTHSERELFERQQAWSIRAMNFSSKRPRAEEYAPVIFAQDAYKHVVSIDMLSGAEDRGNLLRARESGKVVLTAPFQLLNKRIGVVLTYAVYKSELPLNATVHDRIQSSIGYLGGVFDIEGHVDKLLEKLAGKEPMTVNIYDTTGESMIRMYGSSNESASGMCHVSTLDFGDPLRKHEMHCRFTQGPPWPWLAVASSYGTLVISLLVGYIFHFTDKWIAKVEDGYKATDMQMPAKDEFAATERISDMERDLKEDALFFDTTKSPSLLEISRLLNHRDPAQNVHQEEQELNLPLEAQDKLKETERKLGRMSKFITKVMKLTSASIRCLPSRFHCFNKKVWSISLLGFLLFILVIGAFDQPYNQPLGMGGEGDNNMMLKNFGFSRGRLLIDTLHGTWTKRGVQSSDTIRVDLRKMTRNNDSSGQQLKHWSSHKSSEIPAVLYVPMNGKQVIVHCNLIVDEKALVNWISNGDTDQSSKYQKETAGIQNRTDKPHLPANKSHKTTVSPWIVLLPVIMLVLLGSIIWRRCNDHRRRVQQKELELLGIMGPSRFQLQDLVAATGNFADENKLGQGGFGPVYKGYLRDQDLHVAIKVLSRRQSCQEQSAQGLREFKAEVKVMTQLRHRNIVKLVGWSDSKKQLLLVYELMAQGSLDKHLYDPEKILTWQQRYQIKFANLFNSTDKIVLDLGSALLYLHHDCEKCIVHGDIKPANVMLDVSHNAKLGDFGLARLVEHGGEPQTTQVVAGTPGYIDPEFINNRWPRTELDVYSFGIVLLEIACGKRPASRQLPNGASSLLAWVRDLYDQGKILDAADQRLNGEFNQQQMERVIVMGLCCSHQDPIQRPSIVQAMDVL
What is the function of this protein?
Putative receptor kinase that may be involved in cytokinin signaling.
What are the official names of this protein?
Probable kinase CHARK, CHASE domain receptor-like serine/threonine kinase, OsCRL4, OsHKL1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAK_MYCA1
Sequence: MTEPAKLPWSDWLPQQRWYAGRNRRLTGAEPSVIVGLRDDLDLVLVDADYADGSRDRYQVLVCWDAAPVSEYSTVATIGAADDRTGFDALYDDEAPQFLLSLIDSSAVRSASGAEVRFAKEPDAQLPLEAMAHVSDAEQSNTSVIFDRDAIFKVFRRVSSGINPDIELNRVLGRAGNPHVARLLGTYEMAGADGTPETAWPLGMVTEFAANAAEGWAMATASVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLAETLGTSQAAFPVDNVLARLSSTAALVPELTEYAATIEERFAKLATETITVQRVHGDLHLGQVLRTPESWLLIDFEGEPGQPLEERRAPDSPLRDVAGVLRSFEYAAYGPLVEQGSQNTDKQLAARAREWVERNRTAFCDGYAAASGIDPRDSAPLLAAYELDKAVYEAGYEARHRPGWLPIPLRSIARLTAA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity).
What are the official names of this protein?
Maltokinase, MaK, Maltose-1-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: AB16B_ARATH
Sequence: MKTWGSMRSIFMHADGVDWMLMGLGLIGAVGDGFITPILFFITAMLLNDFGSFSFNDETFMQPISKNALAMLYVACASWVICFLEGYCWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLSEKLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGISRKIREEYNEAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQGLAKGIAIGSNGIVYAIWGFLTWYGSRMVMNYGYKGGTVSTVTVCVTFGGTALGQALSNLKYFSEAFVAGERIQKMIKRVPDIDSDNLNGHILETIRGEVEFNNVKCKYPSRPETLIFDDLCLKIPSGKTVALVGGSGSGKSTVISLLQRFYDPNEGDILIDSVSINNMQVKWLRSQMGMVSQEPSLFATSIKENILFGKEDASFDEVVEAAKASNAHNFISQFPHGYQTQVGERGVHMSGGQKQRIAIARALIKSPIILLLDEATSALDLESERVVQEALDNASVGRTTIVIAHRLSTIRNADIICVLHNGCIVETGSHDKLMEIDGKYTSLVRLQQMKNEESCDNTSVGVKEGRVSSLRNDLDYNPRDLAHSMSSSIVTNLSDSIPQDKKPLVPSFKRLMAMNRPEWKHALCGCLSASLGGAVQPIYAYSSGLMISVFFLTNHEQIKENTRIYVLLFFGLALFTFFTSISQQYSFSYMGEYLTKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAKDANVVRSLVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMISVQPVIIVCYYIQRVLLKNMSKKAIIAQDESSKLAAEAVSNIRTITTFSSQERIMKLLERVQEGPRRESARQSWLAGIMLGTTQSLITCTSALNFWYGGKLIADGKMVSKAFFELFLIFKTTGRAIAEAGTMTTDLAKGSNSVDSVFTVLDRRTTIEPENPDGYILEKIKGQITFLNVDFAYPTRPNMVIFNNFSIEIHEGKSTAIVGPSRSGKSTVIGLIERFYDPLQGIVKIDGRDIRSYHLRSLRQHMSLVSQEPTLFAGTIRENIMYGRASNKIDESEIIEAGKTANAHEFITSLSDGYDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATSALDSQSERVVQDALEHVMVGKTSVVIAHRLSTIQNCDTIAVLDKGKVVESGTHASLLAKGPTGSYFSLVSLQRKVRYV
What are the official names of this protein?
ABC transporter B family member 16, ABC transporter ABCB.16, AtABCB16, Multidrug resistance protein 18, P-glycoprotein 16.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GPMA_YERPP
Sequence: MAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTFDFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDERFPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGVPLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ADPRH_STAAC
Sequence: METLKSNKARLEYLINDMHRERNDNDVLVMPSSFEDLWELYRGLANVRPALPVSDEYLAVQDAMLSDLNRQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKITRGYNLSAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEAFNRDAE
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (By similarity).  Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L, by releasing ADP-ribose from the target protein.  May be involved in the modulation of the response to host-derived oxidative stress.
What are the official names of this protein?
Protein-ADP-ribose hydrolase, SpyMacroD.
Protein: FNIP1_CHICK
Sequence: MESPLFELNSALSAASSKSEAMLCSISSKGSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSAKRKIEDVSVSKLCSDAQVRVFGKCCQLKPGGDSSSSLDSSINSSSSFSDAKEQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSIYGSLNTLQDSLEFINQDSNTLKPDHSTIMNGLLGNIVHSNPMDMPGREQNEDRDSGIARSASLSSLLITPFPSPGSSFNKSCASSYQRRWRRSQTTSLENGVFPRWSMDESFNLSDDSSGPSPGIVRKKKIAIGVIFSLSRDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQLCLVLLICLMLVFKAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENAAKNQFLPALLTAVLTNHLAWVPTVMPNGQPPIRIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLAKTVVVGKRHDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEVEESEYVLVTMHKNRGNLLPKESEEMRTPNCSCKNCKCPISLAQNIEGVSQQEREDAQNTPKVELETSSDESRTIVPDDGQEDAADGHQPRTCQDTKVESVVCTGSSSPEKRVLAESGLEATANMWRNEDVLEAGSQAISATRSPGIAVEKKPPDKLFCDAFPCSAAEAQTKVTFLIGDSMSPDSDIELRSQAVVEQIARHHSPPTAEEGVSADQNCEAKQTVEDQNRDCGTAEPFPQVASEHQSWNPNAYNAEGMSLFDDNFTDDGSVETRTMDDLPGQAAAELLTHNSNLEFSKKLCTKTSKPPSEFCKFMDSVRQETYKNCFAEQDQREKISIRVPHGDRENAEKKVAPGIDWDIPRNESSDSALGDSESEDAGHELTRPSSNYYGGEQEDWAEEYEIPFPGSKLVEVNSVQPSIANFGRSLLGGYCSSYVPDFVLQGIGSDEKLRHCLVSDLSHAVQHPVLDEPIAEAVCIIADTDKWTVQVASSQRRMIDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLKGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL
What is the function of this protein?
Binding partner of the GTPase-activating protein FLCN: involved in the cellular response to amino acid availability by regulating the mTORC1 signaling cascade controlling the MiT/TFE factors TFEB and TFE3 (By similarity).  In low-amino acid conditions, component of the lysosomal folliculin complex (LFC) on the membrane of lysosomes, which inhibits the GTPase-activating activity of FLCN, thereby inactivating mTORC1 and promoting nuclear translocation of TFEB and TFE3.  Upon amino acid restimulation, disassembly of the LFC complex liberates the GTPase-activating activity of FLCN, leading to activation of mTORC1 and subsequent cytoplasmic retention of TFEB and TFE3 (By similarity).  Required to promote FLCN recruitment to lysosomes and interaction with Rag GTPases.  In addition to its role in mTORC1 signaling, also acts as a co-chaperone of HSP90AA1/Hsp90: inhibits the ATPase activity of HSP90AA1/Hsp90, leading to activate both kinase and non-kinase client proteins of HSP90AA1/Hsp90.  Acts as a scaffold to load client protein FLCN onto HSP90AA1/Hsp90 (By similarity).
What are the official names of this protein?
Folliculin-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the FNIP family.
What are the subcellular locations of this protein?
Lysosome membrane. Cytoplasm, cytosol. Note=Localizes to lysosome membrane in amino acid-depleted conditions and relocalizes to the cytosol upon refeeding. Colocalizes with FLCN in the cytoplasm.
Protein: RUVB_CLOBL
Sequence: MENRMVTPFDVEDDREQYSLRPTTLKEYIGQKKVKANLDIFIKAAKKRSESLDHVLFYGPPGLGKTTLANIIANEMTGNLKVTSGPAIEKAGDLAAILTSLTDYDVLFIDEIHRLNRSIEEILYPAMEDYALDIVIGKGAAAKSIRLDLPKFTLIGATTRVGLLTSPLRDRFGMLCAMEFYTDEELMEIVVRSAAILNVNICREAAFEIGKRSRGTPRIANRLLKRVRDYCDVKHDGDIDLQGAKAALDLLEVDKEGLDKIDNKILEAIIFNFKGGPVGLETLAYFIGEELDTIEDVYEPYLIQKGFIMRTPRGRVASEKAYNHFGVTKKEEKDNQVSIFNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATPB_ARIMA
Sequence: MRINPTTSGPGVSTLEKKNPGRXAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQQVNVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTFPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLDVESXLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.