PharMolix/UniProtQA huggingface dataset:
Protein: OPSD_CHEAU
Sequence: MNGTEGPYFYIPMVNTTGIVRSPYEYPQYYLVNPAAYAALGAYMFLLILIGFPVNFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIALWSLVVLAVERWMVVCKPISNFRFGEDHAIMGLAFTWVMAAACAVPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVIYMFVCHFLIPLVVVFFCYGRLLCAVKEAAAAQQESETTQRAEREVSRMVVIMVVAFLVCWCPYAGVAWYIFTHQGSEFGPLFMTFPAFFAKSSSIYNPMIYICMNKQFRQCMITTLCCGKNPFEEEEGASTTSKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: ACLA1_ORYSJ
Sequence: MARKKIREYDSKRLLKEHLKRLAGIDLQILSAQVTQSTDFTELVNQQPWLSTMKLVVKPDMLFGKRGKSGLVALNLDIAQVKEFVKERLGVEVEMGGCKAPITTFIVEPFVPHDQEYYLSIVSERLGSTISFSECGGIEIEENWDKVKTIFLSTEKPMTPDACAPLIATLPLEARGKIGDFIKGVFAVFQDLDFSFLEMNPFTIVNGEPYPLDMRGELDDTAAFKTSRSKWGNIEFPLPFGRVLSSTEGFIHDLDEKTSASLKFTVLNPKGRIWTMVAGGELENYAEYSGAPNEEEVLQYARVVLDCATADPDGRKRALLIGGGIANFTDVGATFSGIIRALREKESKLKAARMHIYVRRGGPNYQTGLAKMRKLGAELGVPIEVYGPEATMTGICKQAIECVMAAA
What is the function of this protein?
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives.  May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids.  In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains (By similarity).
What are the official names of this protein?
ATP-citrate synthase subunit alpha chain protein 1, ATP-citrate synthase A-1, ATP-citrate lyase A-1, Citrate cleavage enzyme A-1.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RRAAH_BURM9
Sequence: MMFATTDLCDAHEDRLAAGTLRVLEPVFRPFGGVRRFAGPAATLKLFEDNSLVRTALEQDGAGRVLVVDGGGSLRCALVGGNLGKLAEKNGWAGIVVNGCVRDSDELAECRVGVLALAAHPRKSDKRGAGVSDAPVDVRGTRIVPGDWIYADADGVLVSDDALLE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ODP2_ZYMMO
Sequence: MSIEVKMPALSPTMTEGTLAKWLVKEGDAVKAGDILAEIETDKAIMEFETVDAGIIAKILVPEGSENIAVGQVIAVMAEAGEDVSQVAASASSQISEPSEKADVAQKETADSETISIDASLDKAISNAGYGNKTENMTASYQEKAGRIKASPLAKRLAKKNHVDLKQVNGSGPHGRIIKADIEAFIAEANQASSNPSVSTPEASGKITHDTPHNSIKLSNMRRVIARRLTESKQNIPHIYLTVDVQMDALLKLRSELNESLAVQNIKISVNDMLIKAQALALKATPNVNVAFDGDQMLQFSQADISVAVSVEGGLITPILKQADTKSLSALSVEMKELIARAREGRLQPQEYQGGTSSISNMGMFGIKQFNAVINPPQASILAIGSGERRPWVIDDAITIATVATITGSFDHRVIDGADAAAFMSAFKHLVEKPLGILAQ
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: NEU4_CATCO
Sequence: MSVCAVLLLCVAGLLCLSSACYIQNCPRGGKRALLEPVSRQCLACGPGDKGRCLGPSICCGEEIGCLVGSPWMARCQEEEYLPSPCQTAGKLCGSDAGPCAAPGVCCGTEGCKLDPNCSEDSESEEPADQNTLGASPGELLLRLLHPNNRKHNQY
What is the function of this protein?
Vasotocin is an antidiuretic hormone.
What are the official names of this protein?
Vasotocin-neurophysin VT 2.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_HUMAN
Sequence: MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES
What is the function of this protein?
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network.  Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane.  Binds to calmodulin.  Calmodulin binds preferentially to the beta subunit.
What are the official names of this protein?
Beta-adducin, Erythrocyte adducin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. Adducin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FDHE_SALDC
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLRMDLTARIKDANDQGKPPLDIHVLPRDKHWHTLLHSMIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPLIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I75A3
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEGMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNAKIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHERGINSNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: FEMX_STAAM
Sequence: MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
What is the function of this protein?
Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (GlcNAc-(beta-1,4)-N-acetylmuramic acid(-L-Ala-D-iGln-L-Lys-D-Ala-D-Ala)-pyrophosphoryl-undecaprenol), using glycyl-tRNA(Gly) as donor, in a ribosome-independent mechanism.  Involved in methicillin resistance.
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_SHEON
Sequence: MLLKELSSLASPLSQSQVDKLKQLTAELNSVQLAWVSGYLAATANTSGSAIQVAASVTEAQAAQTVTILYGSQTGNGRGIAKALAEKAKTQGYSVNLASMGEYNVRQLKQETLLLLVVSTHGEGEAPDDAIELHKFLATKRAPQLNNLHYSVLALGDSSYEFFCQTGKDFDARLSALGAKALLPLVECDVDYEAAAGQWHADVLTAVKPLIQTTANVVALNEINSTSAQVASESEFTKQNPYRAEVLVSQKITGRDSDRDVRHVEIDLGESGLHYEVGDALGVWFSNSEILVGEILAGLGLAADAKVTVGSESISLKQALIDKKELTQLYPGLVKAWAELSASSELLALSEDKEQLRQFILNHQFVDLVTNYKLPAEANLDANKLLELLRPLTPRLYSIASSQTEVDTEVHLTVALVEDEHQGQTRFGGASHFLASAQEGAEVKVYVEPNKHFRLPENPDTPVIMIGPGTGVAPFRAFMQERVAQGAKGDSWLFFGNPHFEQDFLYQTEWQQYLKNGDLTRIDVAFSRDQAHKIYVQHRIKEQGQALWQWLQNGAHLYICGDAERMAKDVHQALLAVAVEFGGLSSEAAEEYFETLRSHKRYQKDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: RL18_YERP3
Sequence: MDKKAARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEILVAASTVEKAINEQLKYAGNKDAAAAVGKTIAERALEKGITKVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GPMI_METFK
Sequence: MTVTPALLVILDGFGYREDSHDNAIALANTPNIDRFWTQYPHTLINASETFVGLPRGQMGNSEVGHLNIGAGRVVFQDFERINQAIASREFFSNPVLIEAVNKAKAGHKAVHILGLLSDGGVHSHQDHIHATIEMAVNAGVEKVYVHAFLDGRDTPPISAKPYLEKLEQACASIGGGKIASICGRFYAMDRDKRWPRVEAAYNLITDGQGEFASASALQGLEAAYARDEKDEFVKATAIAAAGEQPVTMEDGDVVIFVNFRSDRARQLTHALLDPDFEGFNRRRQPKLAGFYTLTLYDKAETRAKPIFAPVEIRNTFGEYVAQHGLKQLRIAETEKYPHVTFFFNGGEEQVFAGEDRILVPSPKVATYDLQPEMSAYEVTDRLEAAILSRKYDAIICNYANCDMVGHSGDLSASIKAVETIDTCIARIVKAMESIGGQMIITADHGNVEQMRDYENNQPHTQHTTNQVPLFFIGKPATLAAPGTGSLCDLAPSLLAMMGLKQPPEMTGKSLVAFQAA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: C7A14_PLAGD
Sequence: MDSLFIIISLVIVILTTIFILSNLLSKKTILLPGKTGLPLIGESIDYFNKLRTGINEKFVMERKLKYASDVFKTSILGENMAFLTGPEGNKFLFSNENKLVQVWWPSSVDSIIKKSHNKSAQAESAKVRVLLPPFLRAHAIKHYVSTMDSELRQHVADFWVGRDEVEVCPLVRKYTFALAVRLFLSVRDPGELEALARPFEEAAGGIIAIPINFPGTRFNRGIKASQRIRKVIGGIIEQRRKDLSEGKATPSQDLLSHMIVEVDRRNAENPDIAPATDSDISSDILGLLIGGYDTINTTIVFVMMTLVEYPDVYDQVLKEQREIAASKAPGELLNWDDLGKMKYSWNVACEVLRLRPPTVGAFRVAKTDFNYGGYTIPKGWKLHYIPHFTQKNPDYFPNPEKFDPSRFAGDGPAPYTFVPFGGGPRMCPGNEYARAEILVFMHNIILRYNWEKLIPNEKVVIDPLPRPSQGLPIRLIPHKA
What is the function of this protein?
Involved in triterpenoid saponin biosynthesis in roots (PubMed:28371833).  Catalyzes the hydroxylation of beta-amyrin at the C-16 beta position to form maniladiol (PubMed:28371833).  Is also able to oxidize oleanolat to cochalate (PubMed:28371833).  Has weak activity catalyzing the three-step oxidation at C-28 of beta-amyrin to form oleanolate (PubMed:28371833).
What are the official names of this protein?
Beta-amyrin 16-beta-monooxygenase, Beta-amyrin 16-oxidase, Cytochrome P450 716A141.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL30_RUEST
Sequence: MAKTIVVKQIGSPIRRPAEQRATLIGLGLNKMHKTRELEDTPSVRGMVNKIPHLVEIVEERD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYR_PELPB
Sequence: MKEFFRPVISNALHSAGITTDKQIIIEQPADKKFGDFSTNIALLAAKECRRNPRELAQTIIEHLSFPPDTIAKIEVAGAGFINFYLTPLFIMQSVEQVLLDGDEYGKGESGKGEKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLFATQGYAVTREYYFNDAGRQMQILGESVRFRYLERCGETIEFPATHYQGEYIGEIAEELFNDHGTALADSTDVQIFKKRAEEIIFASIRKTLERLGIRHDSFFNEHTLYTPDAGGVTGNQRVIDALREKEFIAEYDGATWFLTTKLGQEKDKVLIKSSGEPSYRLPDIAYHITKYERGFGMIVNVFGADHIDEYPDVLEALKILGYDTRHIKIAINQFVTTTVDGQTLKMSTRKGNADLLDDLIDDVGADATRLFFIMRSKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLLRMAQQEIGFDATSSPELHLLQRLTSPAELQLGSALLDYPDMIKTSLRLLEPQKMVEYLHSLAECFHRFYQECPILKAEPDIARARLFLSVATRQVLRNGFRILGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_ACIBS
Sequence: MKSLWLDIGNTRLKYWITENQQIIEHAAELHLQSPADLLLGLIQHFKHQGLHRIGISSVLDTENNQRIQQILKWLEIPVVFAKVHAEYAGLQCGYEVPSQLGIDRWLQVLAVAEEKENYCIIGCGTALTIDLTKGKQHLGGYILPNLYLQRDALIQNTKGIKIPDSAFDNLNPGNNTVDAVHHGILLGLISTIESIMQQSPKKLLLTGGDAPLFAKFLQKYQPTVETDLLLKGLQQYIAHYPKD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCPD_HELPY
Sequence: MIKSWTKKWFLILFLMASCSSYLVATTGEKYFKMATQAFKRGDYHKAVAFYKRSCNLRVGVGCTSLGSMYEDGDGVDQNITKAVFYYRRGCNLRNHLACASLGSMYEDGDGVQKNLPKAIYYYRRGCHLKGGVSCGSLGFMYFNGTGVKQNYAKALFLSKYACSLNYGISCNFVGYMYRNAKGVQKDLKKALANFKRGCHLKDGASCVSLGYMYEVGMDVKQNGEQALNLYKKGCYLKRGSGCHNVAVMYYTGKGVPKDLDKAISYYKKGCTLGFSGSCKVLEEVIGKKSDDLQDDAQNDTQDDMQ
What is the function of this protein?
May hydrolyze 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives (By similarity).  Binds to penicillin.
What are the official names of this protein?
Putative beta-lactamase HcpD, Cysteine-rich protein D, Penicillin-binding protein 4, PBP 4.
What is the protein family that this protein belongs to?
Belongs to the hcp beta-lactamase family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIE_PSESM
Sequence: MSQGVEFNRLMLDMRAMQMDAMSAPKPVSGAQEAGASSFADMLGQAVNKVAQTQQASSQLANAFEVGKSGIDLTDVMISSQKASVSFQALTQVRNKLVQAYQDIMQMPV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CLPX_HELPJ
Sequence: MNETLYCSFCKKPESRDPKKRRIIFASNLNKDVCVCEYCIDVMHGELHKYDSKYDRMDSLLALKRDRLRRMESSAYEEEFLLSRIPAPKELKAVLDNYVIGQEQAKKVFSVAVYNHYKRLSFKEKLKKQDNQDSDLELEHLEEVELSKSNILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNVQKAQKGIVFIDEIDKISRLSEHRSITRDVSGEGVQQALLKIVEGSLVNIPPKGGRKHPEGNFIQIDTSDILFICAGAFDGLAEIIKKRTTQNVLGFTQEKMSKKEQEAILHLVQTHDLVTYGLIPELIGRLPVLSTLDSISLEAMVDILQKPKNALIKQYQQLFKMDEVDLIFEEEAIKEIAKLALERKTGARGLRAIIEDFCLDIMFDLPKLKGSEVRITKDCVLKQAEPLIIAKTHSKILP
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: KWAA_ECORM
Sequence: MQRNTYNKVGLYILSLAMLFVFIIILTAKIPFCFTSDCSFIGLKKLVLTNIVPIVCFVFFLFSIYFYNRLKNITKYNGQDSVKITSCQSESYESLTFLATYIVPFMGFSFEDMQKNIAYLLLVVVIGIIFIKTDKYYANPTLALFGFKLYRVNILHPGSGETKNLIAISNDVLKVDDNVYYSFFDEFVFIARKKI
What is the function of this protein?
Component of antiviral defense system Kiwa, composed of KwaA and KwaB.  Expression of Kiwa in E. coli (strain MG1655) confers resistance to phages lambda and SECphi18.
What are the official names of this protein?
Kiwa protein KwaA.
Protein: SAR1_ASPCL
Sequence: MWIINWFYDVLASLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVATLQPTAHPTSEELAIGNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPESKAELDALLAMEELSKVPFLILGNKIDHPDAVSEDELRHQLGLYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  Sar1 controls the coat assembly in a stepwise manner.  Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex.  These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase sar1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CCNA1_HUMAN
Sequence: METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
What is the function of this protein?
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions.  May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
What are the official names of this protein?
Cyclin-A1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU4LM_ONCKI
Sequence: MTPVHFSFTSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQMEATGYSVAPMLLLAFSACEASAGLALLVATARTHGTDRLQSLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TNP3_ECOLX
Sequence: MLKKPSGREADMPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRGDHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRREHAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGATTLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTISGPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVLVAFVLAWETLALDDALEVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYLLKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHLLNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRRGYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQEAIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGFHGIVIPGTLRDSIFVLEGLLEQETGLNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQSDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLRPLKEASEAENVA
What is the function of this protein?
Required for transposition of transposon Tn3.
What are the official names of this protein?
Transposase for transposon Tn3.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.