PharMolix/UniProtQA huggingface dataset:
Protein: SGK2_RAT
Sequence: MASSPVGVPSPQPSRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTMSSSSGASSAFLGFSYAQDDDDILDS
What is the function of this protein?
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation.  Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1. 3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
What are the official names of this protein?
Serine/threonine-protein kinase Sgk2, Serum/glucocorticoid-regulated kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPE_MYCGI
Sequence: MSARDGNTASEWVPTGSVTVRVPGKVNLYLDVGDRRQDGYHELTTVFHAVSLLDEVTVRTADTLSLEHVGEGADSLPTDERNLAWRAAELMAEHVGRAPDVAISIEKTIPVAGGMAGGSADAAAVLVAMNSLWELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHWVLAFSPGGLSTAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQPAALSLDPALRRTLRAGLDAGALAGLVSGSGPTCAFLCTSAGAAVDIGTDLAGAGVCRTVRVASGPVQGARVVPAPSTAG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ARCA_RHIE6
Sequence: MRGFGVHSEVGKLRTVMVCRPSLAHQRLTPANCHDLLFDDVLWVHEAQKDHFDFVLKMQERGVEVLELHDLLGQTLANQQARDFLLDRRITPNVLGSQIAEAMRPWLDEMPAAQLAAFMIGGIAISDLPEVRAKSLMLSALPETDFVIPPIPNTLFQRDPSCWIYGGVTCNPMFWPARRAETLIQRAIYKFHPIFLGGDFQIWWGDSDQPFANASMEGGDVMPIGNGTVLIGMGERTTYQAVGQVAQALFRSKAAKRVIGCLMPKSRAAMHLDTVFSFCDRDVVTLFAEVVDQVRCYSMYPKDDDGTFEIHPENRPMLDVVAEALDLPQLRTVETGGNSYQAEREQWDDGNNVVALEPGVVVAYDRNTYTNTLLRKAGIEVITIRGSELGRGRGGGHCMTCPIWRDPAY
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_GEOSM
Sequence: MLTKRIIPCLDVKGGRVVKGVQFLGLRDAGDPVEIAELYDQQGADELTFLDITASSDDRDIIIDVVRRTAERVFMPLTVGGGVRVVEDIRRLLNAGADKVSINTAAVHRPEFVSEAAEKFGSQCTVVAIDARSRAGGGWEVYTHGGRNPTGIDAVEWAQRMESMGAGEILLTSMDRDGTKDGYDLPLTRAVVDAVSIPVIASGGVGGLSHLYDGFTQAGASACLAASIFHYREYTIEEAKSYLRERGVPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIP1_SAPOC
Sequence: VTSITLNLANPTAGQYSSFVDKIRNNVRDP
What is the function of this protein?
Exhibits N-glycosylase activity (PubMed:7737197).  Catalyzes the release of one adenine from a ribosome (PubMed:7737197).  Acts as a ribosome-inactivating protein and inhibits protein synthesis in a rabbit-reticulocyte lysate system and in various cell lines (in vitro) (PubMed:7737197).
What are the official names of this protein?
rRNA N-glycosylase, Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: Y1333_METJA
Sequence: MPSPKIQEIINELDNLMNRERKYIELVATVEYLLNLIEPSKREKFKEALYDAETVEDVYELIKAIKLQLGMQGARRYLLTLEGQ
What are the official names of this protein?
Uncharacterized protein MJ1333.
Protein: M2_I02A3
Sequence: MSLLTEVETLTRNGWECRCSDSSDPLVVAASIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: LPXC_CAMJJ
Sequence: MKQLTLAKTVKGVGIGLHKGEPIEITLEPLEANSGIVFFRSDLNASYKASPENVINTQMATVLGDDRGFISTIEHLMSAINAYGIDNVRIVLNANEAPVMDGSSISFCMMLDEAEVKELDAPKKIMVIKKPVEVRDGNKFVRLTPTKEPRINYTIKFDNAVIGEQSYNFEFSKKNYIENIARARTFGFLKDVQALRSMNLALGGSLENTIVVDENRILNPEGLRFKDEFVRHKILDAIGDLTLLGYRVFGDYISYAGSHHLNHLLTKEVLKDKDAYEIVSLEKTTQKAYEKVFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: BPT_HYPNA
Sequence: MKFSDPHLLPAGLERSLRFYVTNPSPCPYLPDRKERKAFTNLAIPEADALHNVLSQSGFRRSQSIAYRPACTRCNACKSVRVATREYDISRNDRRVIARNAHLVRRPVAAQATREQFRLLKSYVVTRHDNGGMSDMTYRDYVAMVGGSPVQSLIFEYRDGPEPDAPLVAAAITDVLRDGLSMVYTFFDPAKTSQSLGHYLILDHIRHAHDLGLPHLYLGYWVKGSPKMDYKRRYKPLEVLDGDRWRPLRDDE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSMT_HALHR
Sequence: MNTTTEQDFGADPTKVRDTDHYTEEYVDGFVDKWDDLIDWDSRAKSEGDFFIQELKKRGATRILDAATGTGFHSVRLLEAGFDVVSADGSAEMLAKAFENGRKRGHILRTVQVDWRWLNRDIHGRYDAIICLGNSFTHLFNEKDRRKTLAEFYSALNPEGVLILDQRNYDGILDHGYDSSHSYYYCGEGVSVYPEHVDDGLARFKYEFNDGSTYFLNMFPLRKDYTRRLMHEVGFQKIDTYGDFKATYRDADPDFFIHVAEKEYREED
What is the function of this protein?
Catalyzes the methylation of glycine and sarcosine to sarcosine and dimethylglycine, respectively, with S-adenosylmethionine (AdoMet) acting as the methyl donor (PubMed:10896953, PubMed:11319079).  It has strict specificity for glycine and sarcosine as the methyl group acceptors (PubMed:11319079).
What are the official names of this protein?
Glycine/sarcosine N-methyltransferase, GSMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Protein: RL13_CHLTR
Sequence: MEKRKDTKTTLAKASDDRNKAWYVVNAEGKTLGRLSSEVAKILRGKHKVTFTPHVAMGDGVIVINAEKVRLTGAKRAQKVYHYYTGFISGMREVPFENMIARKPAYVIEHAVKGMLPKTKLGRRQMKSLRVLKGSSYAQYEAIKPIVLDA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NAGB_BREBN
Sequence: MKLVIVKDYAELSRKAAEMLVSEVKANPKTVLGLATGGTPVGMYRELIKLSQAQSIDYSQASSFNLDEYVGLSSTHPQSYRSYMEENLFNHINIPAEKTHVPVGNTTDHLAECARYEEAIRLAGGIDIQVLGIGNNGHIGFNEPGSPADSLTRVVQLTDSTIEANARYFDSVEQVPTQAVSMGIKTILGAKKVVLLASGEAKAEAVRLMLEEEPTADVPASLLQLHRDVTVIVDQEAASKLTTSILAGTKPSGS
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ST2A8_MOUSE
Sequence: MTDEFLWIEGIPFPTVYYSQEIIREVRDRFVVRDEDTIIVTYPKSGTHWLNEIVCLILTKGDPTWVQSTIANERTPWIEFENNYRILNSKEGPRLMASLLPIQLFPKSFFSSKAKVIYLIRNPRDVLVSGYHYFNALKQGKEQVPWKIYFENFLQGKSYFGSWFEHACGWISLRKRENILVLSYEQLKKDTRNTIKKICEFLGENLESGELELVLKNISFQIMKERMISQSCLSNIEKHEFIMRKGITGDWKNHFTVAQAEAFDKAFQEKAADFPQELFSWE
What is the function of this protein?
Hepatic sulfotransferase involved in the maintenance of bile acid homeostasis and energy balance.  Catalyzes the transfer of sulfonate group from 3'-phosphoadenylyl sulfate (PAPS) to the 7-alpha hydroxy group of primary bile acids to form 7-monosulfate derivatives in the pathway of bile acid elimination.  Displays high catalytic efficiency toward cholate, chenodeoxycholate and their glycine and taurine conjugates.
What are the official names of this protein?
Sulfotransferase 2A8, SULT2A8, Glycochenodeoxycholate sulfotransferase 2A8, Liver sulfotransferase-like protein, L-STL.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TPRKB_HUMAN
Sequence: MQLTHQLDLFPECRVTLLLFKDVKNAGDLRRKAMEGTIDGSLINPTVIVDPFQILVAANKAVHLYKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISANDTSILIVYIEEGEKQINQEYLISQVEGHQVSLKNLPEIMNITEVKKIYKLSSQEESIGTLLDAIICRMSTKDVL
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:28805828).  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:28805828).  TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex.  TPRKB is not required for tRNA modification (PubMed:22912744, PubMed:28805828).
What are the official names of this protein?
EKC/KEOPS complex subunit TPRKB, PRPK-binding protein, TP53RK-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: SC31B_ARATH
Sequence: MACIKGVGRSASVALAPDAPYMAAGTMAGAVDLSFSSSANLEIFKLDFQSDDRDLPLVGEIPSSERFNRLAWGRNGSGSEEFALGLIAGGLVDGNIDLWNPLSLIGSQPSENALVGHLSVHKGPVRGLEFNAISSNLLASGADDGEICIWDLLKPSEPSHFPLLKGSGSATQGEISFISWNRKVQQILASTSYNGTTVIWDLRKQKPIINFADSVRRRCSVLQWNPNVTTQIMVASDDDSSPTLKLWDMRNIMSPVREFTGHQRGVIAMEWCPSDSSYLLTCAKDNRTICWDTNTAEIVAELPAGNNWNFDVHWYPKIPGVISASSFDGKIGIYNIEGCSRYGVEENNFGTAPLKAPKWYKRPVGASFGFGGKLVSCHARAPAKGTSSILSEVFLHSLVTEQSLVSRTSEFEAAIENGDMTSLRGLCEKKSEETESEEEKETWGLLKIMFEEEGTSRTKLISHLGFTLPVAEKDQAVDGLSSDLNGIRLEDTAADALDLDDSNEAAAFAMDNGEDFFNNFPAKPDTPVSTSAKDFMPSDTDFSTKGEETQEMQEEEEESSDPVFDNAIQRALIVGDYKEAVDQCITANKMADALVIAHVGGTALWESTREKYLKTSSAPYMKVVSAMVNNDLRSLIYTRSHKFWKETLALLCTFAQGEQWTTLCDALASKLMAAGNTLAAVLCYICAGNVDRTVEIWSRSLANERDGRSYAELLQDLMEKTLVLALATGNKKFSASLCKLFESYAEILASQGLLTTAMKYLKVLDSGGLSPELSILRDRISLSAEPETNTTASGNTQPQSTMPYNQEPTQAQPNVLANPYDNQYQQPYTDSYYVPQVSHPPMQQPTMFMPHQAQPAPQPSFTPAPTSNAQPSMRTTFVPSTPPALKNADQYQQPTMSSHSFTGPSNNAYPVPPGPGQYAPSGPSQLGQYPNPKMPQVVAPAAGPIGFTPMATPGVAPRSVQPASPPTQQAAAQAAPAPATPPPTVQTADTSNVPAHQKPVIATLTRLFNETSEALGGARANTTKKREIEDNSRKLGALFVKLNSGDISKNAADKLAQLCQALDNNDFSTALQIQVLLTTSEWDECNFWLATLKRMMVKARQNVR
What is the function of this protein?
Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.
What are the official names of this protein?
Protein transport protein SEC31 homolog B, SEC31-like protein B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum.
Protein: PG062_VARV
Sequence: MNSHFASAHTPFYINTKEGRYLVLKAVKVCDVRTVEFEGSKASCVLKVDKPSSPASERRPSSPSRCERMNNPGKQVPFMRTDMLQNMFAANRDNVASRLLS
What is the function of this protein?
Plays an essential role in virion assembly and morphogenesis.  Also plays a role in the inhibition of host immune response by dysregulating mTOR.  Sequesters host RICTOR and RPTOR, thereby disrupting mTORC1 and mTORC2 crosstalk.  In turn, blocks the host antiviral response in part through mTOR-dependent degradation of cGAS, the primary poxvirus sensor.
What are the official names of this protein?
Phosphoprotein OPG062, Phosphoprotein F17.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG062 family.
Protein: YXFA_LACLA
Sequence: MQGVLLALVPMFAWGSIGFVANKFGGDAKQQTLGMTLGAFVFALIVFLFRMPTLTWQIFLIGFIGGLLWAIGQFGQFNSMKYMGVSVASPLSSGSQLVIGGLIGVFAFHEWTKQIQFILGFIAMAVLVVGFYFSAKRDPENAVVEEGRNYTKGLTALTYSTLGYVIYVILFNNLAVLWFNVHFDTLTIILPMSVGMIFGALVMGRFKIKMEKYVYQNMIVGAMWGVGNIFMLMAASAAGNAIAFSFSQLGVIVSTIGGILFLGEKKTKKELVYVGIGIVLFVTGAILLAIVKSKG
What are the official names of this protein?
Putative sugar uptake protein YxfA.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H3_MARPO
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVESYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS8_ROSCS
Sequence: MSVNDPIADMLTRIRNACMARHATVSIPSSKMKLAIAQILKREGFIQDFTVQEGKPYSTIVITLKYTPDRRPVITGLKRVSKPGLRIYTKRADIPRVRGGLGLSILSTPRGVMAGHEAWQQRVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PRMB_BURPS
Sequence: MTTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLDARLAPDEIDAVLAVIERRATERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGLQPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVDLSADALAVAKINRDNYGLDERIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGADGMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHASELPAVAG
What is the function of this protein?
Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.
What are the official names of this protein?
50S ribosomal protein L3 glutamine methyltransferase, L3 MTase, N5-glutamine methyltransferase PrmB.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
Protein: 6PGD_LACLA
Sequence: MAQANFGVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVYKEHQDKNLVLTKTLEEFVGSLEKPRRIMLMVQAGAATDATIKSLLPLLDKGDILIDGGNTHFPDTMRRNAELADSGINFIGTGVSGGEKGALLGPSMMPGGQKEAYDLVAPIFEQIAAKAPQDGKPCVAYMGANGAGHYVKMVHNGIEYGDMQLIAESYDLLKRVLGLSNAEIQAIFEEWNEGELDSYLIEITKEVLKRKDDEGEGYIVDKILDKAGNKGTGKWTSESALDLGVPLPLITESVFARYISTYKDERVKASKVLSGPAVNFSGDKKEVIEKIRKALYFSKIMSYAQGFAQLRKASEEFDWDLPYGTIAQIWRAGCIIRAEFLQNITDAFDKDSELENLLLDDYFVDITKRYQEAVRDVVSLAVQAGIPIPTFTSAISYYDSYRSENLPANLIQAQRDYFGAHTYERTDKAGIFHYDWYTED
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: ATP8_LOXAF
Sequence: MERMDIIIWLLAVVIVLTTLMIFLHLKTLKIIRLLFPISKELSKKSCVFPWKKKWTKNYPPSSMYP
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ERTS_BOVIN
Sequence: ISHGFRYDAIAKLFRPFFCGDGYGHRIGETVYYAGSLKYCARSFDVGAEIICKGFYYFGIYKRRVSEV
What are the official names of this protein?
Erythrodihydroneopterin triphosphate synthetase.
Protein: RL5_HAEI8
Sequence: MAKLHDYYRDQVVSELKNKFGYKSVMQVPRIEKITLNMGVGEALTDKKLLDNAVADLAAISGQKPLVTKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKNDEEGQALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYL_PROMT
Sequence: MNNTTSDINDQRYEPREVEAYWQKEWASDDLYRTNTEVNKENTFYALSMFPYPSGSLHMGHVRNYVITDVLARYKRMKGFNVLHPMGWDSFGLPAENAAIEREISPSTWTDKNISQMKDQLDRLGLSIDWSKEVTTCKEEYYKWTQYIFNQLHKNNLAYQKKATVNWDPIDQTVLANEQVDAEGKSWRSGAKVEKKELNQWFLRITSFAEDLNKDLIKLNDWPDRVRVMQKNWIGKSIGAEITFEIKNSDQKITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQKLGMYLGVDAINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYVIKPNIDEDESYLNAEFVDKGIMINSDKFNGIESDIAKTQILEFGSNSNWAKPKITYKLRDWLISRQRYWGCPIPIINCKKCGQVRVPDNDLPVVLPIDIKLTGKGKSPLTTKTEWINTCCPKCGTEAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHAILHLLYSRFLTKALKKCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNPKDPLTGENIEIIYEKMSKSKYNGVDPSVVIDKYGADTARMFILFKAPPEKDLEWDDSDVEGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITDDLDNLQFNTAISELMKVVNGLSLIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTIGNTQSIHLQSWPEFDAGAIEQDTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMDGKEPKRIIVVPNKLVNIVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFB_ECO5E
Sequence: MKITLSKRIDLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTGNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: APT_RHOOB
Sequence: MTDHSAARDAVTRLTRWADDFPQPGVRFADLTPVFSDADGFRVVVDALAACAPATEVIAAVDARGFLLGGGVARELGSGVVAVRKSGKLPPPVLSQSYTLEYGTATLEIPAGSIGLDGRSVLVVDDVLATGGTLDATARLVESAGARVIGIAVVLEIAALGGRERLGKYPLTSLVTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNS_SALPA
Sequence: MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMEEQDKQLEDFLIKE
What is the function of this protein?
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction.  Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome.  As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes.  A subset of genes are repressed by H-NS in association with other proteins (By similarity).
What are the official names of this protein?
DNA-binding protein H-NS, Histone-like protein HLP-II, Protein B1, Protein H1.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NDHK_PIPCE
Sequence: MNSMKFPLLDRTTQSSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAILDAITKLRKKVSREIYEDKIGSQRENRYFTTNHKFHVPKSHVGRSTHIENYDQGLLSQSSSTPEIASENFFKYKSLVPNYDMN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.