PharMolix/UniProtQA huggingface dataset:
Protein: RIR1_HAEIN
Sequence: MNKSLMVTKRDGTQEQINLDKIHRVITWAAEGLDNVSVSQVELRSHIQFYEGIRTSDIHETIIKAAADLISKDSPDYQYLAARLAIFHLRKKAYGHFDPPRLYDHVKKLVRMEKYDQALLDDYTREEWDTMDGFIDHWRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYLLVSASLFSKYPKETRLDYVKRFYDATSTFKISLPTPIMAGVRTPTRQFSSCVLIECDDSLDSINATASAIVKYVSQRAGIGINAGAIRALGSEIRGGEAFHTGCIPFYKYFQTAVKSCSQGGVRGGAATLYYPIWHLEAENLLVLKNNRGVEDNRVRHMDYGVQLNKLMYQRLIKGSEITLFSPSDVPGLYEAFFADQDKFEELYVKYEQDPTIRKRTVKAVEIFSLLMQERASTGRIYIQNVDHCNTHSPFDPQVAPVRQSNLCLEIALPTKPLQHINDENGEIALCTLSAFNLGKIENLDELEELADLAVRSLDALLDYQDYPVVAAKRSSLARRSLGIGVINYAYYLAKNGVRYSDGSANDLTHRTFEAIQYYLLKASMNLAKEQGACEYFNETTYAKGILPIDTYKKDLDSLTQEPLHYDWESLRKDIQEFGLRNSTLTALMPSETSSQISNATNGIEPPRGHVSIKASKDGILKQVVPEYENLMDNYELLWDIPSNDGYLHLVGIMQKFVDQAISANTNYDPKRFEDGKVPMKVLLKDLLTAYKYGLKTLYYQNTRDGAEDVQEDLDDGCAGGACKI
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: SPEH_BACLD
Sequence: METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQAKAKAQAL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: IHFA_HAEIN
Sequence: MATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSSRPGRNPKTGDVVPVSARRVVTFKPGQKLRARVEKTK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DEN5A_MOUSE
Sequence: MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPLADGGDQSGMEDGEGIPGTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDFKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQRKLTSGSLSTSGILLDSERRKSDASAVMSPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVECVMVRNEVTGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNDVVPEENWHTRARNFCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).  Involved in the negative regulation of neurite outgrowth (By similarity).
What are the official names of this protein?
DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1.
What is the protein family that this protein belongs to?
Belongs to the RAB6IP1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane.
Protein: RL21_PELUB
Sequence: MSYAIIQTGGKQYKVKAGEILKIERLEDSKPETKIEFKEILAYGDDKTIEVGSPVVEGAKVEADLVENGKNRTILIFKKRRRQNSRRKNGHRQQYSLIRISKIFSKDGKVLSEAEKMVKPTKKVEKVETEVASK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CLPX_MYCMM
Sequence: MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKSRDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSERRDKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ARFP_ARATH
Sequence: MINVMNPMKGGTEKGLDPQLWHACAGGMVRMPPMNSKVFYFPQGHAENAYDCVDFGNLPIPPMVLCRVLAIKYMADAESDEVFAKLRLIPLKDDEYVDHEYGDGEDSNGFESNSEKTPSFAKTLTQSDANNGGGFSVPRYCAETIFPRLDYNAEPPVQTILAKDVHGDVWKFRHIYRGTPRRHLLTTGWSNFVNQKKLVAGDSIVFMRAENGDLCVGIRRAKRGGIGNGPEYSAGWNPIGGSCGYSSLLREDESNSLRRSNCSLADRKGKVTAESVIEAATLAISGRPFEVVYYPRASTSEFCVKALDARAAMRIPWCSGMRFKMAFETEDSSRISWFMGTVSAVNVSDPIRWPNSPWRLLQVAWDEPDLLQNVKRVNPWLVELVSNVHPIPLTSFSPPRKKMRLPQHPDYNNLINSIPVPSFPSNPLIRSSPLSSVLDNVPVGLQGARHNAHQYYGLSSSDLHHYYLNRPPPPPPPSSLQLSPSLGLRNIDTKNEKGFCFLTMGTTPCNDTKSKKSHIVLFGKLILPEEQLSEKGSTDTANIEKTQISSGGSNQNGVAGREFSSSDEGSPCSKKVHDASGLETGHCKVFMESDDVGRTLDLSVLGSYEELSRKLSDMFGIKKSEMLSSVLYRDASGAIKYAGNEPFSEFLKTARRLTILTEQGSESVVV
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Could act as transcriptional activator or repressor.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin response factor 16.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_PSE14
Sequence: MTTRKYFGTDGIRGRVGQFPITPEFMLKLGWAAGMAFRKMGACRILVGKDTRISGYMFESALEAGLSAAGADVLLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHYDNGIKFFSGQGTKLPDEIEMMIEELLDAPMTVAESENLGKVSRINDAAGRYIEFCKSSVPTSTDFAGLKVVIDCAHGATYKVAPNVFRELGAQVVVLSAQPDGLNINKNCGSTHMEALQAAVVAEHADMGIGFDGDGDRVLMVDHTGTIVDGDELLYIIARDLHERGRLQGGVVGTLMSNLGLELALAEQSIPFVRANVGDRYVIAELLERNWQIGGENSGHIVCFQHATTGDAIIASLQVILALRRSGISLAEARLKLRKCPQILINVRFAGSGVDPVSHPSVQQACARVTEQMAGRGRVLLRKSGTEPLVRVMVEGEDETQVRSYAEELAKLVAEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ARLY_ACIET
Sequence: MSSSSASQPSHDQLATKAQAWSALFSEPMSDLVKRYTSSVFFDKRLWQADIAGSLAHAEMLAAQGIISAQDHADIQKGMAQITQEIASGAFEWKLDLEDVHLNIEARLTQLVGDAGKRLHTGRSRNDQVATDVRLWLRGEIDLIEGLLSELQLSLVEVAEQNVEVILPGFTHLQVAQPVSFAHHLLAYVEMFARDAERMRDVRRRVNVLPLGSAALAGTTYPLDRERVAKTLGMEGVCQNSLDGVSDRDFAIEFTAAASLCMVHVSRLSEELIIWMSQNFGFIKIADRFTTGSSIMPQKKNPDVPELARGKTGRVVGHLMGLITLMKGQPLAYNKDNQEDKEPLFDTVDTLKDTLRIFAEMIGGQMNPATGCKDGGITVNAEAMRAAALKGYATATDLADYLVKKGLPFRDAHETVAHAVKAAVSHSVDLSELPLAVLQGFHPAIEKDVFDALSLQGSLNARNTLGGTAPAQVRTQLARHRARLSA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_RHILO
Sequence: MSRTCELTAKAVQTGNNVSHANNKTKRRFLPNLVNVTLISEALNQNVRLRISANALRSVEHRGGLDAFLAKADVKELSQRARLLKKQIAKKLAEQVAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ULAA_MYCPN
Sequence: MLNKIKLQQKRKLIIGWSVFALINLVVILLTVLLRAGLPNLVSKGVTPFSAQAFGDAFIFLITRVYLDNFLRQPALLLGVITLIGYLALGRGGVQSVVGALKTVIGFILLSIGSGVLVSTARPVFDTIKGLGGTGVVLLDPYFSLASANDFFTNSFLNNDYVSLIAFSLLVGFIVNIIFVGLKRWTNTNSIMVTGHVMLQQAAVVTTLFYIVLFRQIPLLGTGIAYGAQAGLVIISGIFLGVYWSTASTGTYLVTNKVTNNAGFSIGHQQMLGIMTVAKLGKYFGDKNDSAEHKKLPKALKIFEDNIFTQTIIILSLFVVLFIVILASYKGDKPLLINWDKFGAINGLEIWNTTFGGANFTLNIIGGALKMVASLIAIMTGVRMFITELQQAFQGISEKVVPGAVVAVDIAAVYGFSINSVTFGFLSGVIGQFLAVAIMAGISYIPGNQFSFVAIPLFITLFFNSGAFGVYANAEGGWKAALLLPGIIGFLEIIVISFALRTVSNAYQASALLDAKQSFDLKALMGNSLDNNNGSALKTAVEKVVNATGVNRITEAQSFVKSDSFNSLKAVNSTLAQAIEWISKSASPVDNGFIGMADWNLYFGLLVWIGAYNVIGGWILVILATVGLILLAQIIDNGKQTKVTKLQQLLKINPQLDLNN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIC component, Ascorbate-specific permease IIC component UlaA.
What is the protein family that this protein belongs to?
Belongs to the UlaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN271_MOUSE
Sequence: MEIQFSYESQDHHFLSDGETKIKIGEPATEEEMTGKIGTVTEESGSLEEDVPHDSRGKEFREFGEELNDQMLFRRRQYNCDECDQSFAWSTGLIRHQRTHWKPYECEECGKAFRMSSALVLHQRIHTGEKPYPCSWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLMIHQRIHTGEKPYQCSHCSKSFSQHSGMVKHLRIHTGEKPYMCNHCYKHFSQSSDLIKHQRIHTGEKPYKCDVCGKAFSQSSDRILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYKCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCTKSFSRLSDLINHQRIHTGEKPYPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDKCGKTFSQSSNLILHQRIHTGEKPYPCNSCSKSFSRGSDLIKHQRVHTGEKPYTCNLCSKSFSQSSDLTKHQRVHSGEKPYHCSSCNKAFRQSSDLILHHRVHTGERPYACTQCPRSFSQKSDLIKHQRIHTGEKPYKCMCGKAFSQCSAFTLHQRIHTGEKPYPCAQCGKSFSQRSDLVNHQRVHADQKLQM
What is the function of this protein?
May act to control gene activity during the pachytene stage of meiotic prophase.  May function as a transcription activator.
What are the official names of this protein?
Zinc finger protein 271, Zinc finger protein 35, Zfp-35.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENO_CERS1
Sequence: MSTIIDIHAREILDSRGNPTVEVDVTLESGAFGRAAVPSGASTGAHEAVEKRDGDKSRYMGKGVLEAVAAVNGEIAEMLVGFDATEQVGIDRTMIEMDGTPNKGRLGANAILGVSLAVAKAAAEFTNQPLFRYVGGSSARVLPVPMMNIINGGEHADNPIDIQEFMIMPVAAQNVREAIRMGSEVFHTLKKELAAGGFNTGIGDEGGFAPNISSTREALDYILRSIEKAGYKPGEDIYLALDCASTEYFKGGKYEMKGEGKSLTSAENVDYLAALCADYPIISIEDGCAEDDWEGWKLLTDKLGAKVQLVGDDLFVTNPKRLEQGIKAGVANSMLVKVNQIGSLTETLMAVDMAHRARYTNVMSHRSGETEDATIADLAVATNCGQIKTGSLSRSDRLAKYNQLIRIEEMLGEVAEYAGRSILKV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CBPM_SALA4
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: GUAA_ANAMM
Sequence: MSTVAIVDFGSQVTQLIARRVRELGVYSEVFPPSTDFQAMASRGIKIDAFILSGGPNSVQQLHGVPNAVSDVLNLNLQKGVPVLGICYGFQMLAHYFGADVAQSVAREFGRAWLDVIEPSSITEGVWSLGSKVDVWMSHSDSIVGEVPQGFRVVARSADTGAVAFMCNDERKIYGVQFHPEVAHTPGGREMLDNFLKIAGCTRDWTMGSFLHTQIGAIKSATDGGRVVAAISGGVDSSVASVLVHKAIGERLVCVFVDTGLLRKGEAGVVRDLFVGKLNMHVNVLDKSALFMQRLAGVQDPEVKRKIIGETFIEVFEQEAKSLGDIKFLMQGTIYPDVIESGVGESGTKIKSHHNVGGLPEIMNLSLVEPLRHLFKDEVRLLGKELGLPSAILDRHPFPGPGLAVRIMGEVTAERVELLREIDNIYIDMMRDSGLYDHIWQAFAVLVPVRTVGVMGDGRTYGYVCALRAVTSSDGMTADCFPFGETDERKLEFLAFLQKVSRAIVSNLQGVNRVVYDMTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: AROD_DEHMC
Sequence: MKIPPICCVITQLPQAETLKKSEGAAFYELRLDLLGENWRETAVLLNKPFMATCRRSAEGGSFKGNEAERINRLEKAASAGAFMLDIEYSTPNLEEVLGRLRPQAKCLLSHHNFTDTPSAAKLKTLLKDMLTHQADIYKVITTATSINDNINLLNLTKEIPDKKIVAFAMGEPGILSRILCPLAGSPFTYASLNDGNKSASGQMTLAQMIEIYRSVNYANHT
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: RDRP_ESRV9
Sequence: MDTYGSIKRDLKYMYDVEEVFRNTIPKTYFGIDDVEDLHVDEAGISNIHNNITLGTKKCYHLYKKGHRTQVPIYLGSLVTRESNEYEDVSYSYDNLNTIYKDAPVWEPLLNKVSKWYDEGWSVPSSKPIPYDPNYSKCLILSPDKYKKYHKVVVDVDYDAFHWSIDVNSEFMDMPNVIRAWDISTIPQFVDGFPMLKHLIDRSKKEALFYFNYRLIPYVVHNIDKDDDMWREWLSYFLHGDHFKPDRGSYDNFGSLLGHKRLEVALMYHNRIRLMPMSATALDAMNEGAKFLMKDPTYHTAVMKKYNGVLTQYGMAEPLGYNRGWGYTGVTTADSPFILSNVNGADGYTVIDREAVEEAKEIGMQYTPKLVKLQLANMTKTSSPVNLIDSLIGNAIISLTGFAGSEKVSTALDQFEKENFERKVPDELFTAISNVTYEMVRESFQPLERSMLDKRTRLLRLYNAGTSASSSAPPGARYIFNKKMIMYSTFLSKSIDVTDEYAPMSFITSLNFNNKTANILTHPQNYYMYDWHDNHNRIINSGSREVRGGRATRIITPDPPSNYMLLILGALNTVRDMGSHRTGFSNLGMNEVVGSSFLDAVSHDALAPQCLATSSSRSLCAQALDYSTWDRQQGGRIAEAKAHGIMRVANELFPNTNTNLSDVHNLLELPMSSILYLWSESIKSSYKYKIDHSTVAVDAVRSGELTTQFSNHVTNLAALRQYHETYNRTKVPQGFRPIEVAQINIVGDDVNVILRTADRKPFTLRDMEGYHNHTFEKAAEYEFSISKKRSMMSNVATEHIKQYFKMGDILLDVMLSSMTSERNTFREQGYMNGINLLYDIAVTIMARYAQNDKLFEDMMANLPFMEGVVYRHGSQKYHFHPSPCHLLGSGSPEILPSAIDLRTFARVITVLGDYESDLYEAMSSLNATLLSTSGTTQFESQVRKHLSEELGDNIISPVWSEVFYRDEVGYEMVTKHNKLTPEGHREYLVDRIISTLSNREKLIMNNADIIEKLLSGKLKKVKRYFQEIKFKMSNMPITGLPDRKIEGVSELSSPYRAADVGMRRVHKCIGLSRRNLKFPSVTERLSRLLKSYGLVTQADSAKILSAAAGLGRSSTRYRNLGTDLGLSDMHASSFAQRLPALLTQYEIENASGSFTFYDTVSRTYDVSEASMNERVGDVSNNPIARANSSTSTYYRFRGMLHCLYGARFGLSLHASVE
What is the function of this protein?
RNA-directed RNA polymerase that is involved in transcription and genome replication.  Following infection, it catalyzes the synthesis of fully conservative plus strands.  After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion.
Protein: APAH_NITEU
Sequence: MATYAIGDLQGCHRHFLELLDLIGFNATRDRLWLVGDIVNRGPDSLSLLRTLIELGDAVTMVLGNHDLHLLAVAAGSIRQQHGDTLQPVLEASDSSRLLDWLRHQQLFHHEDEYVLVHAGLLPNWSIEQAQILAQEVETIIRGDRFQTFSRSMYGNVPDHWHDRLQGEDRWRVIINAMTRMRVCSPEGRMNFSCKGELSSVPDGLLPWFEIPWRASKDTTIVFGHWSALGLHLTPNLIALDTGCVWQGCLTSVRLEDRKVFQVPCVRH
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: YIGF_SALTY
Sequence: MDKDYINDGSLSEKWKYRFSFYDQHGFPGFWKVSPEYKQAFKALKPRQRLTIQINFIAFFFSWIYLFVLGLWKKAIIVILLGIVAIFIGALIGVNILGLVVAAYVGVNTNKWFYEKEVKGINTWSL
What are the official names of this protein?
Uncharacterized protein YigF.
Protein: CONG1_LUPAN
Sequence: MARNMAHILHILVISLSYSFLFVSSSSQDSQSLYHNSQPTSSKPNLLVLPVQEDASTGLHWANIHKRTPLMQVPLLLDLNGKHLWVTCSQHYSSSTYQAPFCHSTQCSRANTHQCFTCTDSTTTRPGCHNNTCGLLSSNPVTQESGLGELAQDVLAIHSTHGSKLGPMVKVPQFLFSCAPSFLAQKGLPNNVQGALGLGQAPISLQNQLFSHFGLKRQFSVCLSRYSTSNGAILFGDINDPNNNNYIHNSLDVLHDLVYTPLTISKQGEYFIQVNAIRVNKHLVIPTKNPFISPSSTSYHGSGEIGGALITTTHPYTVLSHSIFEVFTQVFANNMPKQAQVKAVGPFGLCYDSRKISGGAPSVDLILDKNDAVWRISSENFMVQAQDGVSCLGFVDGGVHARAGIALGAHHLEENLVVFDLERSRVGFNSNSLKSYGKTCSNLFDLNNP
What is the function of this protein?
Sulfur-rich seed storage protein that remains undegraded at germination.
What are the official names of this protein?
Gamma conglutin 1, Conglutin gamma.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CSK2B_CHICK
Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2.  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).  Participates in Wnt signaling.
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta, Phosvitin.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: NSP5_ROTHP
Sequence: MSLSIDVTSLPSISSSIFKNESSSTTSTLSGKSIGRSEQYISPDAEAFNKYMLSKSLEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSTQSRPSSNVGCDQLDFSLTKGVNVSANLDSCISISTDHKKEKSKKDKSRKHYPRIEADSDSEDYVLDDSDSDDGKCKNCKYKKKYFALRMRMKRVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: GLMU_ACIET
Sequence: MTALDIIIMAAGKGTRMKSRIPKVLQRLAGRPLLHHVLGQAASLQARRVVVVTGHGATEVEAACAGLAGAGGTFDLKFVRQEPQLGTGHAVQQATPALAGDGTVVVLSGDVPLTQAATLRALVEAGAGERLALLTVRLPNPTGYGRIVRGEGGTVQRIVEHKDANDAERAIDEVYSGIMAVPAQRLAGWLARLTNDNAQGEYYLTDIVSMAVADGVPVAAHCIGDALQVAGVNSPAQLAELERAHQRAQAAALMEQGVRLADPARFDLRDDARSGARGEILCAQDVEIDVGCIFTGRVELGEGARIGAYCHISNATIAAGAVVHPFTHIDGEKAGAHVGEGALIGPFARLRPGAQLGREVHIGNFVEVKNSTLADGAKANHLAYLGDASVGERVNYGAGSITANYDGANKHRTVIEADVHIGSNCVLVAPVTIGAGGTVGGGSTITKDTPPGGLSVARGRQVSIANWKRPAKQAKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_ACIBS
Sequence: MARLKARYNDELKAKLQEELSIKNVMEIPRITKITLNMGVGAAATDKKLLDGAVADMQLIAGQKPVVTLARKSIAGFKIRDGWPIGCKVTLRGDQMYEFLDRLISIAIPRIRDFRGFSAKSFDGRGNYSMGLKEQIVFPEIDFDKIDRIRGMDITITTTARTDDEGRALMRAFGFPFK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRUB_BRUSU
Sequence: MARRGKKKGRPISGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEATKTVPYVMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVPPQFSAIKIDGERAYDLAREGETVEIPAREVEIDRLEIVGFPDADRTEFEVECSKGTYVRSLARDMGRDLGCYGHISDLRRVEVAPFTDEDMVTLAKLEAVWPPLPPKDEDGNVIEPAPRRDFSALDALVIDTGAALDCLPQVPLSDDQAQRVRLGNPVILRGRDAPLEADEACVTTRGKLLAIGYIEHGQFKPKRVFTAG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NADE_SULTO
Sequence: MMPEYVRKKLTLDFGQVTDYIVRRIREYIEESKKEGGIIGLSGGIDSSVTTILLSRATNNFYILLMPTSSTPQKDIEDAMKIIKIVNGENKYSYINIDEIINEFSSIVNISDKIVIGNIKARVRMTLLYAFAQKMNYLVIGTGDKSEIMLGYFTKYGDGGVDVLPIGDLYKTQVRMLGNYLGVPEEIVKKPPSPALWEGQTAEGEIGLDYETIDSILYLKFEEMREPEEIAEMTKTSYDKVIKIINMVKTSQHKRLPPEIFRLSGRAINSDWRYPRQWG
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.