PharMolix/UniProtQA huggingface dataset:
Protein: SELD_SHEB5
Sequence: MSDSPVTLPESIKLTEYSHGAGCGCKISPKVLSTILASQLPVFTDPNLLVGNQSRDDAAVYKLNDDIGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPIMAIAILGWPINKLPAEVAQQVVDGGRQACMEAGIMLAGGHSIDAPEPIFGLAVTGQIALTDLKQNDTAKAGDRLYLTKPIGIGILTTAQKQKKLQDEDSHIAVNAMCQLNTIGTTIAKISGVNALTDVTGFGLAGHLLEMCQGAKLTAKLKFDAVPLLPRALDYLALGCVPGGTHRNYDSYGEHLPELSEHQKAILCDPQTSGGLLVAVSAEAEAELIDLLDAHHIAPICIGSLETPTTEVNVVLC
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ISPE_CYTH3
Sequence: MISFPNAKINLGLSVLSKRPDGYHNIETCFYPIPWNDMLEIIPAKETVFTSSGNNIPGTSASNLCLKTYTLLKEKYPLSPVHIHLHKRIPIGAGLGGGSSDAAFTCKLLNDVFALKLSAAEMEDIVRPVGSDCAFFIENTSILAHEKGDYFSHPGIVNLSGKWIYLIHPGIHVATKEAYDGVVPNTDRKPIGDILKQPLSVWKAELVNDFERSVFEKYPAIKTLKEQMYKQGAAYAAMSGSGSTVFGIFNTKPETFHENTSNIQSCIAPL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NEP_I83A8
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TILS_LEIXX
Sequence: MRAALAAAAALPVPDAEGDHGPARPHPLAPGALVLIGLSGGADSLALAAAAAFEAPRAGFRSGAIVVDHGLQPGSAEVAAGAACQARALGLGPVLVERVRVEAAGGPEGAARAARHTAFDSAARATAAARILLAHTLDDQAETVLLGLARGSGPSSLQGMLPDTGRLLRPFLGLRRATTRAFCADSGLEPWDDPHNDDPAYTRVRVRSAVLPVLEQELGPGVAEALARTAEQLREDDQALDSLALEGAQELVSQADDGSVALEVRGLAAGPPALRQRIIRLVVSAEFGVSLSRSHTLAVAALIADWHGQGPLSLPGVRVVRQNGLLTFHPHT
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_ESCF3
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NADK_STRP7
Sequence: MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BRADU
Sequence: MAHHDPIHLIAPRAGLAQLNERSRDIFRQIVESYLATGEPVGSRNISRLIAMPLSPASVRNVMADLEQLGLIYAPHTSAGRLPTELGLRFFVDALMQVGDLNDAERQSIQSQLTSVGQAQSVEAALDQALTRLSGLTRAAAVVLTPKSNARLKHIEFVRLEPEKALVILVGEDGQVENRVLTLPPGVPSSAITEAGNFLNSRIRGRTLAEARLELETALGEARAELDQLTQKVISAGIASWSGGENEDRQLIVRGHANLLEDLHALEDLERVRLLFDDLETKRGVIDLLGRAETAEGVRIFIGSENKLFSLSGSSTIISPYRDAAGHIVGVLGVIGPTRLNYARVIPTVDYAARIVSRLLGG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: MASZ_PSEAB
Sequence: MTERVQVGGLQVAKVLFDFVNNEAIPGTGVSADTFWTGAEAVINDLAPKNKALLAKRDELQAKIDGWHQARAGQAHDAAAYKAFLEEIGYLLPEAEDFQAGTQNVDDEIARMAGPQLVVPVMNARFALNASNARWGSLYDALYGTDVISEEGGAEKGKGYNKVRGDKVIAFARAFLDEAAPLESGSHVDATSYSVKNGALVVALKNGSETGLKNAGQFLAFQGDAAKPQAVLLKHNGLHFEIQIDPSSPVGQTDAAGVKDVLMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAEEVSKGGSTFTRTMNPDRVYTRADGSELTLHGRSLLFVRNVGHLMTNDAILDKDGNEVPEGIQDGLFTSLIAIHDLNGNTSRKNSRTGSVYIVKPKMHGPEEAAFTNELFGRVEDVLGLPRNTLKVGIMDEERRTTVNLKACIKAAKDRVVFINTGFLDRTGDEIHTSMEAGAVVRKGAMKSEKWIGAYENNNVDVGLATGLQGKAQIGKGMWAMPDLMAAMLEQKIGHPLAGANTAWVPSPTAATLHALHYHKVDVFARQAELAKRTPASVDDILTIPLAPNTNWTAEEIKNEVDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQLLANWLRHGVISQEQVVESLKRMAVVVDRQNASDPSYRPMAPNFDDNVAFQAALELVVEGTRQPNGYTEPVLHRRRREFKAKNGL
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPGF4_MOUSE
Sequence: MVAAHAAHSQSSAEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPAHTITKVPSEKILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRAANQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP.  Seems not to activate RAB3A.  Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
What are the official names of this protein?
Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-dependent Rap1 guanine-nucleotide exchange factor, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: ETTA_ECOL6
Sequence: MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAGKSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALKRLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKIANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHDRYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWVRQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYGDRLLIDSLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVDQFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGERGRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIATHILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK
What is the function of this protein?
A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio.  Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation.  ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
What are the official names of this protein?
Energy-dependent translational throttle protein EttA, Translational regulatory factor EttA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with ribosomes and polysomes.
Protein: RRF_STRP7
Sequence: MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD1_RHIME
Sequence: MTTIIDGKAVAASINGAIKDANAELQEQTGRKTGLSVIIVGDDPASHAYVGAKSRMAKECGFFSVQHTLPKETTQQELAGLVHQLNADDGIHGILVQLPLPEHLDADAIIQSIRPEKDVDGLHVANAGKLATGDLESGLISCTPAGAMVFVRRVHGRDLSGLNALVIGRSNLFGKPMAQLLLNANATVTIAHSRTSDLASICRNADIVIAAVGRPEMVKANWLKTGATVIDVGINRVPAPEKGENRTRLVGDVAFAECAPFASAITPVPGGVGPMTIAMLMANSVIAAHRASGLKVSERLSKLISG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PHEB1_SYNPW
Sequence: MLDAFSRSVVSADAKTAAVGAGDIAALRQYVAEGNKRLDAVNAITSNASCIVSDAVTGMICENTGLIQAGGNCYPNRRMAACLRDGEIILRYISYALLAGDASVLDDRCLNGLKETYIALGVPAQSAARAVAIMKASATAHIGETNTQANGGAKFRKMETTQGDCSALVAEAASYFDRVISAIA
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
C-phycoerythrin class 1 subunit beta, C-phycoerythrin class I beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the periphery of the phycobilisome rod.
Protein: MANBB_ASPFC
Sequence: MSKLQQFPLSKGWSFRDNEATSEDAWMPVPVVPSVVHQDLQANNKLKDPYIGFNELEARWVNEKSWTYKTVFQKPAAPAGSCIVLAFDGLDTFAKVKLDGNVILENDNMFLARRVDVTKALEAEGDHVLEIDFDCAFLRAKELRKQDPRHNWASFNGDPSRLSVRKAQYHWGWDWGPVLMTAGIWREVRLEVYSARVADLWTEVQLASDHQSAQVTAFVEVESVHSGSHRACFTLSLHGQEITREEIGVTENGTAKATFDVKEPSLWWPHGYGDATLYEVSVSLVKEQEELHRVSKKFGIRTAEVIQRPDKHGKSFFFRVNGVDIFCGGSCWIPADNLLPSITAERYRKWIELMVHGRQVMIRVWGGGIYEDYSFYDACDELGVLVWQDFMFGCGNYPTWPNLLESIRKESVYNVRRLRHHPSIVIWVGNNEDYQVQEQAGLTYNYEDKDPENWLKTDFPARYIYEKLLPEVVQEYSPGTFYHPGSPWGDGKTTSDPTVGDMHQWNVWHGTQEKYQIFDTLGGRFNSEFGMEAFPHMSTIDYFVENEADKYPQSHVLDFHNKADGHERRIATYLVENLRTATDLETHIYLTQVVQAETMMFGYRGWRRQWGDERHCGGALLWQLNDCWPTISWAIVDYFLRPKPAFYAVARVLNPIAVGVRREHHDWSVTHAQPPKTSKFELWVASSRQQEIQGTVELRFLSVNTGLEVRERIVHENVSIVPNGTTNLIVDGLIDHTVHSEPHVLAARIWVDGQLVARDVDWPQPFKYLDLSDRGLEVKKISESEDEQTLLISTKKPVKCLVFEEREGVRISDSAMDIVPGDDQRVTIKGLKPGDAPLKYKFLGQ
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Prefers mannobiose over mannotriose and has no activity against polymeric mannan.  Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity).
What are the official names of this protein?
Beta-mannosidase B, Mannanase B, Mannase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.
Protein: YOJO_BACSU
Sequence: MKFIKFNDSTIDSFLFMMLTDLAKTLTKSEAVEVEYGVQSYYNPFEKKIYMSHFWKDRAAEDMEAGLKSDVYLRSVGTRYSSLHEFANFLNDIHRHLTFKSFAKQLFMLLEDIRIEECIKRERPGTKHVFAKRKDMYRKHFSTQLTLNLERSIFTDALFCAIYFKLTAESPLETLPSMREDIDLMRPFIEQQLLRVYEADSTRQVLKIVEDLMDGLEEVLDKDMLNTYFFLPELDYAKAAEQPLFEEEKKAPKLSDDITLPKQSDGDEDIHEEEMPTWHRETEAPSKSFLQFDIEHGAKSDLGKDASREGDDGDQALGSVQGSARQTKRKDYSKLEALESQKDQPNGAGMADGKENKYAFPIYKEPQPATSEEELSYKQQAKTIESYQKRLKQMIQKTLEHKKTLPRTDLHAGRLNNKLLRYFTERNPRLFYKKQEPSSEIDAVFTLLVDCSASMFDKMDETKRGIVLFHEALKSVAVPHQIVGFWEDTNDATEKSQPNYFNTVIPFQSSLRQDSGPAIMQLEPEEDNRDGYAIRQMTKKMLHRSEAQKFLIVFSDGEPAAFGYEQNGIVDTSEAVIEARKRGIEVINVFLSNSEIEESQMKTIQDMYGKFSIFVPDVDQLPDVLYPLLKKLLHKSIG
What are the official names of this protein?
Uncharacterized protein YojO.
Protein: VF152_ASFWA
Sequence: MYSILIACLVLLLCLIIYVGHRADHARKYLEGMWHGDPVFLKQSGLQSFYLYIQPDHTCFFSVVNKNGEKLMETKIPCTITNKIYMFFKPIFEFHVVMEDIHSYFPKQFNFLLDSAEGKLILENNHVIYAVLYKDNFATALGKTVKKYIT
What are the official names of this protein?
Uncharacterized protein EP152R, pEP152R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus EP152R family.
What are the subcellular locations of this protein?
Virion.
Protein: MUKB_YERPY
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVVNSRHQRVVVGVRLQQVAGRDRKVDIKPFTIQGLPTAIQPTEILTELVAERQARVLSLPELKERVEAMEGVQFKQFNSITDYHSLMFDLGVIPKRLRSSADRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDSALVLRRDLFSSRKQLVTEQYRHVEMSRELAEQSGAESDLETDYQAASDHLNLVQTAMRQQEKIERYQSDLEELTYRLEEQSEVVSEASEQQADNEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYQQALQALERARALCQLPELTADNAEEWLETFHAKEQEATESLLQLEQKLSVADAAHSQFEQAYQLVVNIAGEVSRSEAWQTARELLRDWPSQQHLAERVQPLRMRLSELEQRLRAQQDAERLLQEFCKRQGNAYQPEELEALQRELESQVEELSLSVSDAGERRMAMRQELEQLKLKIQELTARAPVWLAAQDALSQLSEQSGEALEDSRQVTEYMQQLLERERETTVERDEIAASKRAIEAQIERLSQPSGAEDARLIALAERFGGVLLSEIYDDVTIDDAPYFSALYGPSRHGIVVPDLSLVREHLQGLDDCPEDLYLIEGDPQSFDDSVFAVEEHEKAVVVKIADRQWRYSRYPEVPLFGRAARENRLETLYQERDRLAERYATLSFDVQKTQRTHQAFSRFIGSHLAVAFDADPEAEIRLLNTRRGEIERALNAHEDQNQQQRQQFDQAKEGISALNRLIPLVSLLLDETLTDRVEEITEELAEAQEAARYIQQHGVSLTKLEPLLSVLQSDPQQHEQLQESYVLAQNSQRLAKQQAFALTEVVQRRAHFSYTDSAGMLTENSDLNDKLRQRLEQAEAERTRAREQLRQYQSQFTQYSQVLASLKSSYDAKRDMLKELSQELVDIGVPADANAEARARARRDELHAALSTNRSRRNQLEKQLTFCEAEMDSLQKKLRKLERDYHQIREQVVNAKAGWCAVMRMVKDNGVERRLHRRELAYMDGDELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTAREQKLAISSKSVSNIIRKTIHREQNRIRMLNQGLQAVSFGQVKSVRLNVNVREAHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQMDMGQRLPQTIGEELLDYRNYLELEVEVYRGADGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLEMQLIIAAPENISPEKGTTYKLVRKVFQNHEHVHVVGLRGFANEIPSLPPIAAELQQGG
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: YCF15_MAIZE
Sequence: MLIVLFRSKDIRGGRFVRPILIFRTKRSWILFRIGPERRREAEMPTDLCLFSNSPDPIVPVFGTSSAKVTEWVSHQSNPFDKSGVILDIIFYIYRNIIE
What are the official names of this protein?
Putative uncharacterized protein ycf15, ORF 99.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CPS1_ISOJA
Sequence: MLQSMGDGEISISPYDTAWVALVEDDGGGRRQPQFPSSLEWISSNQLADGSWGDAGTFSIFDRILNTLACVVALRSWNIHPHKTEKGIWFMKKNMCRIDEENLEHMPIGFEVALPSLIDIAKKLGIDIPTQTRGLQEIYARREIKLKKIPRDIMHQAPTTLLHSLEGMAGLKWEKLLKLQSEDGSFLFSPASTAFALQQTRDHNCLKYLTNHIHKFNGGVPNVYPVDLFEHLWAVDRLQRLGLSRYFEPEIEECIAYVHRQWTEKGICWARNSQVEDIDDTAMGFRLLRLHGYEVSADVFRHFKSDGGEFFCFKGQSTQAVTGMYNLYRASQLMFPGENILVDAARFSANFLQLKRANNDLFDKWIITKDLPGEVGYALDVPWYASLPRVETRFYLDQYGGDDDVWIGKTLYRMPYVNNNKYLELAKLDYNNCQALHQQEWQNIQKWYRSCSLGEFGMTERSLLQTYYVAAASVFEPEKSQERLAWAKTAILMETITSHFEFQQLSRDQKRAFITEFEHDSILKYTNGGRYKRRSSLVGTLVRTLNHLSLDILLAHGRDIHQPLKNAWCKWLNSWEEGGDAELLVRTLNLMISGGGRRRRWASEELLSSNPKHEQLLKATIGVCDKLRLFQRRKVQGGNGCMNATGITTVEIESEMRELVKLVVTRSSSEDLDSEIKQNFLTIARSFYYAAYCNQGTINFHIAKVLFEKVL
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities (By similarity).  Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to ent-copalyl diphosphate (ent-CPP) (By similarity).
What are the official names of this protein?
Ent-copalyl diphosphate synthase 1, IjCPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
Protein: COMT1_OCIBA
Sequence: MGSATNTPQINSDEEENFLFAMQLASASVLPMVLKSAIELDLLELIKKSGAGAFVSPVDLAAQLPTTNPDAHVMLDRILRLLTSYAILECRLKTLPDGGVERLYGLAPVCKFLTKNEDGVSMAPLTLMNQDKVLMESWYHLSDAVVDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYTGFDGLKTVVDVGGGTGATLNMIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCVKFLKNCYDALPQNGKVILAECVLPEAPDTGLATKNVVHIDVIMLAHNPGGKERTEKEFQGLAKAAGFKQFNKACCAYNTWIMELLK
What is the function of this protein?
Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid.  The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
What are the official names of this protein?
Caffeic acid 3-O-methyltransferase 1, CAOMT-1, COMT-1, S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: RL6_VIBCM
Sequence: MSRVAKAPVAIPAGVEVKLNGQEITIKGAKGELTRVFHNGVVIAQEDNQLTFGPREGVANAWAQAGTARALVKNMVVGVTEGFTKKLVLKGVGYRAAMKGNAVGLTLGFSHPVEHELPAGVKAECPSQTEIVLTGCDKQVVGQVAADIRSYRAPEPYKGKGIRYADENVRSKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS5_BUCBP
Sequence: MSNIGRNVSGDLKEKLISVNRVSKTVKGGRIFSFSALTVVGDGHGKVGFGYGKAREVPSAIQKAMEKARRNMIQVPLNNGTLQYSVTGSYTGSYIFMKPASNGTGIIAGGAMRSVLEVAGVHNVLAKTYGSTNPINVVRATMLVLESMKSPEMIALKRNKLVKEILENSYL
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DEF4_MESMA
Sequence: MKTIVLLFVLALVFCTLEMGIVEAGFGCPFNQGQCHKHCQSIRRRGGYCDGFLKQRCVCYRK
What is the function of this protein?
Dual-function peptide with antimicrobial and potassium channel-blocking activities (PubMed:26817841).  Shows inhibitory activity against Gram-positive bacteria such as S. aureus, B. subtilis, and M. luteus as well as methicillin-resistant S. aureus (MIC=0. 1-20 uM) (PubMed:26817841).  Does not act on bacteria by disrupting membranes (PubMed:26817841).  Also moderately inhibits Kv1. 1/KCNA1 (25. 2% inhibition at 1 uM), Kv1. 2/KCNA2 (30. 5% inhibition at 1 uM), and Kv1. 3/KCNA3 potassium channels (IC(50)=510. 2 nM, 61% inhibition at 1 uM) (PubMed:26817841).  Inhibits potassium channels by interacting with the pore region (PubMed:26817841).  Does not show hemolytic activity (PubMed:27128943).  In vitro, dose-dependently decreases the production of Hepatitis B virus (HBV) DNA and HBV viral proteins in both culture medium and cell lysate (PubMed:27128943).
What are the official names of this protein?
Defensin BmKDfsin4, 4 kDa defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TSI6_PSEAE
Sequence: MTPIEYIDRALALVVDRLARYPGYEVLLSAEKQLQYIRSVLLDRSLDRSALHRLTLGSIAVKEFDETDPELSRALKDAYYVGIRTGRGLKVDLP
What is the function of this protein?
Immunity protein that plays a role in preventing early activation of toxin Tse6.
What are the official names of this protein?
Immune protein Tsi6.
Protein: THIG_CLOD6
Sequence: MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMALRRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISDTRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNRGLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMARAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.