PharMolix/UniProtQA huggingface dataset:
Protein: M1_I88A7
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEVALSYSAGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: DGTP_ECOK1
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: RL33_JANSC
Sequence: MAKPTTIKIRLNSSAGTGHFYVTKKNARTMTEKMVVRKYDPVARKHVEYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MDTF_ECOL6
Sequence: MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITVSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVASNIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPNQVIGVRPNGLEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHLFARFKKA
What is the function of this protein?
Part of the tripartite efflux system MdtEF-TolC, which confers resistance to various compounds.
What are the official names of this protein?
Multidrug resistance protein MdtF.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COCE_CONCL
Sequence: RGVCSTPEGSCVHNGCICQNAPCCHESGCNWANVCPGFLWDKN
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation (By similarity).
What are the official names of this protein?
Mu-conotoxin-like CalTx 12.2.1E.
What are the subcellular locations of this protein?
Secreted.
Protein: NORW_ECOLU
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDACIPLTLIAADSMDEYNKPDLSHVISQRQRADDLTRQTAGEFAEQFNLHLFPHTWIMDIDAEAHVVKSQNNQWQYDKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILATLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCTEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPV
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDRKH_HUMAN
Sequence: MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL
What is the function of this protein?
Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs.  May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
What are the official names of this protein?
Tudor and KH domain-containing protein, Tudor domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Tdrkh family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Colocalizes with pi- and piP-bodies, a subset of the nuage which contains secondary piRNAs. Associated with mitochondria in the germline.
Protein: PERC1_HUMAN
Sequence: MAAGVIRPLCDFQLPLLRHHPFLPSDPEPPETSEEEEEEEEEEEEEEGEGEGLGGCGRILPSSGRAEATEEAAPEGPGSPETPLQLLRFSELISDDIRRYFGRKDKGQDPDACDVYADSRPPRSTARELYYADLVRLARGGSLEDEDTPEPRVPQGQVCRPGLSGDRAQPLGPLAELFDYGLQQYWGSRAAAGWSLTLERKYGHITPMAQRKLPPSFWKEPTPSPLGLLHPGTPDFSDLLASWSTEACPELPGRGTPALEGARPAEA
What is the function of this protein?
Plays a critical role in intestinal function (PubMed:31217582).  Acts by promoting the development of enteroendocrine cells (EECs) of the gastrointestinal tract and pancreas (By similarity).  It is thereby required for normal enteroendocrine peptide hormone secretion (By similarity).
What are the official names of this protein?
Protein PERCC1, Proline and glutamage-rich protein with a coiled coil domain.
Protein: BIOD_WOLSU
Sequence: MKPLFISATGTGVGKSYTTQKLLQSLHQSGRKPLALKPIETGANPTPEDALLHLQLMQKLQLDQGLSLEEICLERYKLPASPWVSAKKEGRCVDVDHLLRRLLEFQKRSDPLLIEGAGGLLVPLLKEYFMIDLAEALEAHMVLVISGKLGGINEALLSLEALQHRQMSYTLVLNLWEEEKRSFEEISAPYWKERPERLFRLDSELEELTQTLLSAI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_ECOLI
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: MATN2_MOUSE
Sequence: MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTAVDYCASENHGCEHECVNAESSYLCRCHEGFALNSDKKTCSKIDYCASSNHGCQHECVNAQTSALCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKHCKRCTEGPIDLVFVIDGSKSLGEENFETVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLRGFSSAKEMKKAVTHMKYMGKGSMTGLALKHMFERSFTQVEGARPPSTQVPRVAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKEGICEALEDSGGRQDSAAWDLPQQAHQPTEPEPVTIKIKDLLSCSNFAVQHRFLFEEDNLSRSTQKLFHSTKSSGNPLEESQDQCKCENLILFQNVANEEVRKLTQRLEEMTQRMEALENRLKYR
What is the function of this protein?
Involved in matrix assembly.
What are the official names of this protein?
Matrilin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: GSH0_BOVIN
Sequence: MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLIREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIIASPPVEDGVNLSLEHLQPYWEELQNLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIRAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKGS
What are the official names of this protein?
Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate--cysteine ligase modifier subunit.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
Protein: Y3156_SHESM
Sequence: MPSFDIVSEVDEVELRNAVENSRRELSSRFDFRGKDASIEYKDHVVTLTAEDDFQCKQLVDILRTQLSKRNVEPSTMDVDEKSVHSGKTFSLKVRFKQGIETDIAKKIVKMVKDSKIKVQSQIQGDTVRVTGKARDDLQAVMALVRQADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein Shewmr4_3156.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: FLY2_ARATH
Sequence: MNNLGNFGVWGFGFFSLSIWFAVLQQANGLRPIRETARSWGDEWLFGKKEKGGAGPFSAWNITGTYRGTWKFLDTVNSSSKFPDFRKESGNSVIELVTSPTKITGVHYVQGAVVFHDVFDNEHNVGGAQIKVEGVYIWPFRQLRLVANSGKKSDSGLEDDYLLSNPYHLLGIFSSQVFQESPRDRILKQKTSPIYEMEKHCNIEIAAQISQSTSSENNGDKDRYQIEGLMESPAVDDEVDCFSPLSLNATSINVEVYYNKAVNYTLMVTFVSFLQVLLLIRQMEHSNTQSGAAKVSIVMIGQQAIMDSYLCLLHLTAGILVESLFNAFATAAFFKFVVFSIFEMRYLLSIWKATRPSTSGEGWETMRRELSFLYSRFYGILLGGILLMYEFHNYMRPILLLMYSFWIPQIVANVVRDSRKPLHPYYILGMTVTRLAIPLYVFGCPKNFMRVEPSKAWCVSLCAFMGFQAGVLLLQHYFGSRCFVPRKLLPEKYSYYRRLDHNVNRSRDCVICMTTIDLRHRINDCMVTPCEHIFHSGCLQRWMDIKMECPTCRRPLPPA
What is the function of this protein?
E3 ubiquitin-protein ligase that may be involved in xylem development.
What are the official names of this protein?
Transmembrane E3 ubiquitin-protein ligase FLY2, Protein FLYING SAUCER 2, RING-type E3 ubiquitin transferase FLY2.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein.
Protein: ISG20_HUMAN
Sequence: MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPFAVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCRRVSLRVLSERLLHKSIQNSLLGHSSVEDARATMELYQISQRIRARRGLPRLAVSD
What is the function of this protein?
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA.  Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner.  May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
What are the official names of this protein?
Interferon-stimulated gene 20 kDa protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20.
What is the protein family that this protein belongs to?
Belongs to the exonuclease superfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.
Protein: UN93L_DROME
Sequence: MTGFTNAGFENDEPVKPKAGFEPDTASLREKVVLNPGEKWRILKNISIISIAFMVQFTAFQGTANLQSSINAKDGLGTVSLSAIYAALVVSCIFLPTLIIRKLTVKWTLVCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQVGQVYAKITEQAVDAIIVRFFGFFFLAWQSAELWGNLISSLVLSSGAHGGGSSSNTTVSEEDLQFCGANFCTTGSGGHGNLERPPEDEIFEISMIYLSCIVAAVCIIAFFLDPLKRYGEKRKGSNSAAELSGLQLLSATFRQMKKPNLQLLIPITVFIGMEQAFIGADFTQAYVACALGVNKIGFVMICFGVVNALCSILFGSVMKYIGRTPIIVLGAVVHFTLITVELFWRPNPDNPIIFYAMSGLWGVGDAVWQTQINGLYGLLFRRNKEAAFSNYRLWESAGFVIAYAYATTLCTQMKLYILLAVLTLGCIGYVIVEILYRKKQRKLKKQEKLEAAEKEKEAAAAAAAAALAAAEAGADGVEETDDELDDLEEDIVVTRL
What are the official names of this protein?
UNC93-like protein.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y7187_DICDI
Sequence: MTIVYCLTKLSNPSSSLRSSSDVSGNQGVEIDFDSNSISWKKWYSGGGGSGGKWDGGGSGGKWNGGGGSGGGSWKKWN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0286915.
Protein: RECA_ECO27
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Plays a role in recovery after DNA ADP-ribosylation.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_STAAN
Sequence: MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_LAWIP
Sequence: MRKFETLLLLSPELSPDAREALLVKLVSIIEKNKGQFTVNHWGMRDLAYPVQKHMRGYYVLLEYTTYPNIIEELERIIRITNGIFKFMTIKLEEHIEEKQLEEVV
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MOAA_PASMU
Sequence: MQTIPIKHVGNDPLVDAFQRRYYYLRLSITDVCNFRCNYCLPNGYQPESNKPSFLTLNEIRLVVKSFANMGTEKVRITGGEPTLRKDFLPIVETIAQNPTIKQIALTTNGYRMAKDVAAWKEAGITSINVSIDSLDARMFHRITGIDKFEDVMRGLERAFEVGYQKIKVNSVLMRDLNDADFNQFLTWIKDKPIQMRFIELMQTGEMDHFFQQHHVSGQLLADKLINAGWTLQSKGLLDGPAKVFKHPDYVGEVGLIMPYEKNFCASCNRLRVSAKGKLHLCLFGEEGITLRDLLQSDDQQLQLQARISSALQGKREHHFLHQGDSGVRANLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: OPN3_HUMAN
Sequence: MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
What is the function of this protein?
G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin (PubMed:28842328, PubMed:31380578, PubMed:31097585).  Binds both 11-cis retinal and all-trans retinal (PubMed:31097585).  Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light (PubMed:28842328, PubMed:31097585).  Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling (PubMed:31730232).  Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade (PubMed:31730232).  Required for TYR and DCT blue light-induced complex formation in melanocytes (PubMed:28842328).  Involved in keratinocyte differentiation in response to blue-light (PubMed:30168605).  Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts (PubMed:31380578).  Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues (By similarity).  May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways (By similarity).
What are the official names of this protein?
Opsin-3, Encephalopsin, Panopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: COAD_ALKMQ
Sequence: MKVGIYPGSFDPITNGHIDIIKRASEIYDRVIVSVMQNPNKNPMFTLGERVALIEQIIQPYSNIEVDCFSGLLIDYAREKGAKVIIKGLRAVSDFEYELQMALMNRKLCPEVETVFLMTNSQYSYLSSSLVKEVAKFKGDVSEFVPEIVLQAMSKKS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_HAEDU
Sequence: MNRDTIFSTPIEKLGDFTFDESVADVFPDMIQRSIPGYSNIITAIGMLAERFVTEGSNVYDLGCSRGASILAIRRNAPTKNFRIIGVDNSRPMVERCRSHLSAYHSDIPVNIVCDDIRNIEIQNASMVVLNFTLQFLPRTDRIALLTKIYHGLNPNGILILSEKFSFVDNTIDELLVDLHHTFKRANGYSELEVSQKRTALENVMLTDSIQTHKNRLQDAGFSQIELWFQCFNFGSMVAIKQSP
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RAP2A_PONAB
Sequence: MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ
What is the function of this protein?
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.  In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK.  Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development.  More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading (By similarity).
What are the official names of this protein?
Ras-related protein Rap-2a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Midbody. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Localizes to midbody at telophase. May also localize to the Golgi and the gelatinase-containing granules of neutrophils.
Protein: RPOB_DAUCA
Sequence: MLRDGNEGMSTIPGFNQIQFEGFCRFMDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSEFYISAGLIWKTSRDMQEQTIFLGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRLELEIDKKARIWARVSRKQKISILVLSSAMGSNLREILENVCYPEIFLSFLTDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQKCELGKIGRRNMNRRLRLDISQNNTFLLPRDILAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLIQDQLGLALVRLENMIRGTIGGALRHKLIPSPQNLVTSTPLTSTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHAKIGRGGSLESPFYEISQRSKGARMLYLSPGKDEYYMVAAGNPLALNQGLQEEQVVPARYRQEFLTIAWEQVHLRSIFSFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVLAIAEHEGKVIYTDTDKILLSGNGDTLNIPLVMYQRSNKNTCMHQKPQVQRGKYIKKGQILAYGAATIGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPERVTREIPHLEAHLLRNLDKNGIVMLGSWVETGEILVGKLTPQMVKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKRVGSSYNPETIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLDRHYRIAPFDERYEQEASRKLVFSELYQASKQTATPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAYILQEMLTYKSDHIRARQEVLGTTIIGGAIPNPEDAPESFRLLVRELRSLALELNHFFVSEKTFKIKRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL6_BORA1
Sequence: MSRIAKYPVELPKGVEASIQQDQITVKGPLGTLVQALTGDVNIVEDAGKLTFAAANDSRHANAMSGTVRALVANMVTGVSKGFERKLTLVGVGYRASVQGEAVKLQLGFSHDILHKLPAGIKAECPTQTEIVIKGANKQVVGQVAAEIRAYREPEPYKGKGVRYADERVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.