PharMolix/UniProtQA huggingface dataset:
Protein: SELD_DESHY
Sequence: MKSFLSSCTTGGCGAKIGPGELSKVLSGLPVFQDPQLLVGFDASDDAAVYQINEDTAIVSTVDFFTPMVEDPRIFGRIAAANALSDVYAMGGSPLFALNLVCYPEREDIQDLGEILAGGAEKLQEAGAVLCGGHSIYDREPKYGLAVTGRLNPRQIWKNNTPQPGDRLILTKPLGVGIVMAALRGEMAEAAAVEAALASMQRLNKYAAEKARDFPIHACTDITGFGLLAHTREMAGGSTTIVLYPSALPYIAQAYTYAQGYLLTAAGQRNRNFMEGAVEFGDTPFPLQELMLDPQTSGGLLLSVPGDCAQEALRAIQEAEPQAALIGEVVSRQALPILLR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: PYRF_EHRCR
Sequence: MFTNPIICALDTHDINHALLLTKMLYGRVSMVKLGLEFFTAYGLSGVQAIADCGVPIFLDLKLHDIPNTVSKAISVIASLNVAMLTIHVSGGREMMIRAMDSISGSVTKLVGVTVLTSMDDSDLKEIGVNESPVQQVMLLSKLAREVGLYGIVCSAFEAKEVRNRYTEKDLKLIVPGIRFDSDCNDQKRVKSPKDAMLAGANYLVIGRPITMSSDPVQTVEDILLSISKCI
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: LRGB_BACC1
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COPZ1_HUMAN
Sequence: MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta-1, Zeta-1-coat protein, Zeta-1 COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: ENO_BURO0
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWDGWKLLTDRLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: MPGP_ECOL6
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLHEANIPVILCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEICQVLNKLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDEHMAQFIARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGRRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_LOXAF
Sequence: MAYPLQLGFQDATSPVMEELLHFHDHTLMIIFLISSLVLYIIMLMLTSKLVHTNMMNVQEMEMIWTILPAIILILIALPSLHTLYMMDEINNPLLTIKTMGHQWFWSYEYTDYEDLAFDSYMITTDSLKFGELRLLEVDNRMVLPTDLPVRVLVSSEDVLHSWAVPSLGLKTDAIPGRLNQVTLTSMRPGLFYGQCSEICGANHSFMPIVLELVPLKYFENWSASLAQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRT4_ASHGO
Sequence: MPRSKRSKLVTLAQTEKKGRENKERIFDEVRQALDTYRYVWVLRLEDVRTPVLQEIRSAWAGSKLIMGRRKVLEKALGGTRETEYKENVSGLVKQCEGMCGLLFTDETPETVTAYFREYRKADYSRAKSRAPLRVEIPAGVVYSRGGQVPAEDDVPMVHSLEPTLRNKFKMPTRIQNGKITLEQPYLVCEAGETLDVRQALILKQFGVAAAEFRVKLAAYYDGEAAAVEEVRINME
What is the function of this protein?
Component of the ribosome assembly machinery.  Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
What are the official names of this protein?
Ribosome assembly factor mrt4, mRNA turnover protein 4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: ENO_SHEB5
Sequence: MAKIINVIGREIMDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRYLGKGVLTAVANVNDLIRTALLGKDATAQAELDQIMIDLDGTENKDKLGANAILAVSLAAAKAAAAFKGIPLYAHIAELNGTPGQYSMPVPMMNILNGGEHADNNVDIQEFMVQPVGAKTFREALRMGAEIFHTLKKVLHDKGLSTSVGDEGGFAPNLASNADALAIIKEAVELAGYKLGTDVTLALDCAASEFYKDGKYDLAGEGKVFDSNGFSDFLKSLADQYPIVSIEDGLDESDWDGWAYQTQIMGDKIQLVGDDLFVTNTKILTRGIENGIANSILIKFNQIGSLTETLAAIRMAKEAGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEQLGEKAPYRGLKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYS_LISMC
Sequence: MLDVKLLRNNFDEVKQKLQNRGEDLGEFEKFGELDKRRRTLIVETEALKSQRNEVSQEIAKLKREKQDADAKIEEMRVVGDRIKTLDIELREIDEKLDMILMSIPNIPHESTPVGESEDDNVEIRKWGEVREFDFEPKAHWDLGTDLDILDFENAAKVTGSRFVFYKKLGARLERALINFMMDLHSNEHGYEEMLPPYMVNRASMTGTGQLPKFEEDAFLIEAEDYFLIPTAEVPVTNYHREDILKAEDLPRKYTAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVQFVKPEDSYAALEKLTGNAEEVLRRLELPYRVLSMCTADLGFTAAKKYDLEVWIPSYNSYREISSCSNFESFQARRANIRFRREPGSKPEYVHTLNGSGLALGRTVAAILENYQDADGSVRIPKVLQGYMGGIEKIELPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CYAP4
Sequence: MPKLKTRKAAAKRFRQTGTGKFTRRKANRNHLLEHKSTARKNKLSHMAIVDERDEERVSLMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RANB1_TOBAC
Sequence: MALPNQQTVDYPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTARLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPFLYLARKLAGDANLHFVESPALAPPEVQIDLAAQQLHEQELLQAAAHALPDDDDEAFE
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran-B1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_MARN8
Sequence: MRIYNTLTQQKEAFKTLEPGKVRMYVCGMTVYDYCHLGHARVLVAFDVVTRYLRHRGYDVHYVRNITDIDDKILRRADENGEVYTDLTDRMIRAMHEDEAKLGVLSPNEEPRATAFIDDIIAMIQKLIAGGHAYAADNGDVYFAVESFPDYGKLSKKKLEDLVAGARVDVQEAKRSPADFALWKAAKPGEVSWQSPWGEGRPGWHIECSAMSTKCLGDTFDIHGGGPDLLFPHHENEIAQSECATGHTFVHTWMHAGAIRVNKEKMSKSLGNFFTIREILEKYPAEVVRYFLVSSHYRSQVDYSEDNLAEAGRTLTKLYHALRGIVPAKEADVAETDHDRRFAEVMDDDFNTAGAIAVLHAVANDINHYRREGDEEAAKRSAAVLVRLGAVLGLLQQNPEAFFQADTGSELTAEDIEAMIQARADARKAKDFAEADRIRDDLLEKGIILDDSREGTTWRRSQD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_CANLF
Sequence: MSMVYINIFLAFILSLMGMLVYRSHLMSSLLCLEGMMLSLFVMMSVTILNNHLTLASMMPIVLLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DCDA_ECOLI
Sequence: MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALKQFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTADVIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGENSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVETVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNGQARLIRRRQTIEELLALELL
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.  Is not active against the DD- or LL-isomers of diaminopimelate.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: DNAK_LEPCP
Sequence: MGKIIGIDLGTTNSCVAVMEGNTTRVIENSEGARTTPSIIAYQEDGEILVGASAKRQAVTNPRNTLYAVKRLIGRKFTEKEVQKDIDLMPYKIAAADNGDAWVEVRGKRMAPPQVSAEVLRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGLDKHGKGDRKIAVYDLGGGTFDISIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDFIIAEFKKDQGVDLSKDVLALQRLKEAAEKAKIELSNSAQTDINLPYITADASGPKHLNIKLTRAKLESLVEELIERTIAPCRTAMKDAGVSVGQIDDVILVGGMSRMPKVQDKVKDFFGKEPRKDVNPDEAVAVGAAIQGQVLGGERKDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKFSQTFSTADDNQPAVTIKVYQGERELASGNKSLGEFNLEGIPPSPRGTPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLSEDEIQKMVRDAEANAAEDKKKVEVVQAKNQGDAMVHSVKKSLTEYGDKLDAGEKEKIEAAMKDVEEAIKGDDKDDIEAKTNTLMTASQKLGEKMYADMQAQQAAGAAAGPAGGEAPKSESKADDADVVDAEFKEVKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PEBA_PROMM
Sequence: MFDPLLEKLHSSIRIQGGETAAVPDGLRECRNEKKNSWIRSWLWQVPGFRRWRVSRLDAGESLQVLNSVAYPNYNIDQPLMGLDLLWFGKRQKLVAILDFQPLIQDQSYLERHFQGLKTLQNRFPELSGEETMRLFDPNQYFSPWLLFCRGGAEKATNSLPEAFNAFLHCYWELHQQNSDKASLIPAAEVKQLQIAYDIYSAERDPAHGLFTSHFGKAWSDRFLHEFLFPASTKADSSPPADADDDLPR
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: GYRA_MYCMA
Sequence: MGNYHPHGNASIYNTLVRMAQPWSLRYPLVNGQGNFGSPGNNPPAAMRYCCTGDALVRLPFGHSVRIGNFVPAACPNSDNAVNLKVLDRHGDPVVADQLFHSGEHQTYTVRTAEGYEVTGTSNHPLLCLVDVGGVPTLLWKLIEEIRPDDHVVLQRTPPVEFGPADWHDVMEALLLGAFISEGFVSEVRAGFNNCDRDYFAMVVGAYDAVVGGRRYVSSRRIASGSTLHELDIQNIKELKEARLGDLCGQRPADKSVPDWLWHSPAAVKRVFLQALFEGGGSCSALPRNMIQISYSTRSRQLAVDVQQMLLEFGIITRRYRHAVGEHKVLITNRAQAELFATRVGFGGAKQEKLTKILGSMPPCAGMDSDHVPGLARFIRKHCGSRWVDKDWLNRHNVDRIQRWRTSGEKILSHIADPDVRAIATDLTDGRFYYAKVASVTEAGVQPVYSLRVDTDEHAFLTNGFVSHNTEAR
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAA_ECOSE
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRTDLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPTGSEWLESVRAYEKAILSQRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_PORG3
Sequence: MKTFQLTGTPRAEFGKKAAKAIRKEDQIPAVLYGGKGEGVNFIVSQDAVRNLIYSPEIFLVELTVEGSGSYKAILKEIQFHPVTDRIIHIDFLQVTDEKPVVMEVPVVLTGHAEGVKAGGKLSLEMRKLKVKALYSEIPEKLDIDVSDLQLGKTIQVGELHFEGLTLMNAKNAVVCAVKLTRAARGAAVKKQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RS18_CAMHC
Sequence: MADKRKYTRKYCKFTEAKIEFIDYKDTALLKYCLSERFKIMPRRLTGTSKKYQEMVEKAIKRARQAALIPYIVDRDNVVVNPFEILG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: THBB_XENLA
Sequence: MPSSMSVRLFTASAAQRKKIQEGDCCVVLAGKTQGRFILIGAVARVSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCKTVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSIVQRPEPTQEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLSSVERIEKCQEGFLLAFEHYINYRKHNIAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
High affinity receptor for triiodothyronine (T3).
What are the official names of this protein?
Thyroid hormone receptor beta-B, TRbetaB, Nuclear receptor subfamily 1 group A member 2-B.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRPB_SHEON
Sequence: MTQSAGLRFRQALANSKPLQIVGTTNAYFALMAEQTGFQALYLSGAGVANASYGLPDLGMTSMNDVLIDAGRITSATQLPLLVDIDTGWGGAFNIARTIKEFEKIGVAAVHMEDQVSQKRCGHRPNKAVVSTEEMVDRIKAAVDARTDPNFVIMARTDAVAVEGLEAGIERAKAYIAAGADMIFAEALTELDQYRHFKAQVKAPILANMTEFGQTQLFNKEELAQAGADMVLYPLGTFRAANQAALKVMQALMNDGHQRNVLDTMQTRADLYKYLGYHAFEDKLDQLFSQDK
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
What are the official names of this protein?
2-methylisocitrate lyase, 2-MIC, MICL, (2R,3S)-2-methylisocitrate lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
Protein: HIS4_SYNY3
Sequence: MKILPAIDLLGGKCVRLYQGDYDQSQVYHEDPVEVARQWQAQGASRLHLVDLDGAKEGQPVNLTAIANIVEALTIPVQVGGGLRDRNRVKQLLDLGVGRVILGTIAVENPDLVGELCAEFPGQIVVGIDARNGKVATRGWLETSTVEAGELAQRMEKLGAAAIIYTDIHRDGTMQGPNLDALRQLASQLTIPVIASGGVSQVEDLLNLLSLESLGVNGVIIGKALYTGDIQLAEAIRAVGNGRWQDVPPLDFPRLG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLBA1_RAT
Sequence: MQGGREVGRESVSDLAEELGEGSLHPTAGGQSGDSLERRRIGYDGPVILPDANANSSRLDEGLSSSRPHPGELGGGWGEFEGFQESSAKSEEFSQSFELLGRAAECQPLRTPSTPKEGGSCQVQQGGPWVTGTAAGPSSESILSYEKVFRLAFQEVPVEQATEDVCSLDRFLETGSEETAPVPRLCSESRKLWRALQNTDTVSASRCLWSESHCRENLFPVLGIDAAQKSLSGDQGHDLEGSDCRKPEDLLGVSGFHLHHCKALIQTKLSGTSGSRQGSLITYSLFLKTPLQGNGRYITIPQKKIFTPRNLKMAFFNNNVC
What are the official names of this protein?
Uncharacterized protein CLBA1, Clathrin-binding box of aftiphilin-containing protein 1.
Protein: MGRB_KLEP3
Sequence: MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFFSGICTINKFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HRCA_XANOR
Sequence: MRASQSPMLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLLAHSVDLASEALVPADADDMVMAGQTRLMGVQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYDRLIPLVQTAADVLGAAMESPGTR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: Y1161_METJA
Sequence: MRDNIRSINKLLIYLVLILSAMFLCQNVFAEDYNAIEITVKNISSGEILYQKIFPKDEAFSDYQVINGFTIDIHYNPNYPGMVYKVHQSNNHFIFNVSGELNWGSYQQSGDIACIVDVIHYDFPPPSNTTSNTTTTSSSSTKAPIPLSVYLAITAFFTYIIYRKSKT
What are the official names of this protein?
Uncharacterized protein MJ1161.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECR_TRIV2
Sequence: MQRLPGVGPKTAQRLALHILKRPESEVEALAQALVEAKKQIGLCSVCFHLSSEPVCEICRNPNRENNTICVVADSRDVIALEKTREFKGKYHVLGGVISPMDGIGPEQLTITPLLRRVSQQQPKEVILAISPSVEGETTTLYVGQLLKPFTKVTRIAFGLPVGGDLEYADEITLARALEGRRELD
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.