PharMolix/UniProtQA huggingface dataset:
Protein: Y670_MYCPN
Sequence: MPELTRFQKFFLTPEKFNKFTRVVGFCGVFALIALSLGIYSYVGQGSIVPKVAALFLIALGGFTLLLSFVINFVALYKRSQLIHLVNRQDRTDLWLQKMANNKQFEQFELFEKGPISADILPTFYPATIYNFELVPKQFKVQYKNGQTLNFAKLSAIKRSTSKNEKVACLVAIIDAVSDQHWFLTKSDFPLINTGFYESLTESNRQNNVLLYTEKDASFNFNQLDKEMIKQVLFNPVNVYANFNVYNNTTHTYLMMSVPITFMDTSLRMEEAVGDLELNITRQAGYDAATLDSFHKVVELLKTKLIGDFNNAETTSATETTVVAEVTEPTTNSKRKPVKAKKAKK
What are the official names of this protein?
Uncharacterized protein MG456 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VASO3_TABYA
Sequence: MKFALFSVLVLMLIATFVAADDCPRICTSDYTPVCGTPSGGRRSANRTFANQCGLDSHNCLNKGDTYDKLHDGECK
What is the function of this protein?
Vasodilator protein that inhibits vasoconstriction of isolated rat femoral artery induced by phenylephrine.  Since platelet aggregation and vasoconstriction are key hemostatic responses, particularly in small wounds, this protein likely participates in the antihemostatic responses during blood feeding.  Blocks L-type calcium channels (Cav1/CACNA1) in left ventricular myocytes isolated from rat hearts.
What are the official names of this protein?
Vasotab-TY3.
What are the subcellular locations of this protein?
Secreted.
Protein: RLP7_KLULA
Sequence: MSQPLNSNPEVLLRKRRNADRTRLEKQELAKKRKEQEEKQKRSKKNRFVRAETIVATTLATEREKTRIRRVRDLENQKVKNDLSHIPSDRDFILRISEREAGSKATSESELQDVDEEDEEDDGLIREKIVYDGEPSLLFVIRVKGPTAVKIPAKAYKVLSLLRLVELNTGVFIKLTKDVYPLLKLVSPYIVIGQPSLASIRSLIQKRSRIMWQRPEDKEPKEIILNDNNIVEEKLGDEGVICIEDIIHEISTLGENFSKCTFFLLPFKLNREVSGFGAISRLNKLKMREQNKKTRQISNAATAPVIQVDIDSMISKLN
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein RLP7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PYRG_BURCJ
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTLVPYVATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISMFSNVPEDAVISVWDADSIYKIPQMLHDQGLDRIICEELKLSPKDADLSMWSALVEKLENPKQEVTIGMVGKYVDLTESYKSLIEALRHASIHTSTKVNIEYIDSEELETNGVDSLKHLDAVLVPGGFGRRGTEGKIAAVRYARESKVPYLGICLGMQLAVIEFARDVVGLKQANSTEFDPDTPERVVALITEWYDREGKVETRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRFVPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALANKQARGVQA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TACAN_RAT
Sequence: MQSPPPDPLGDCLRNWEDLQQDFQGIQETHRLYRVKLEELTKLQDNCTNSITRQKKRLQELALVLKKCRPSLPSESLEAAQELESQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGLPFLLLFLGNFFTTLRVVHQKFHSQQHGSKKD
What is the function of this protein?
Ion channel involved in sensing mechanical pain.  Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli.  May also be required for efficient adipogenesis.
What are the official names of this protein?
Ion channel TACAN, Transmembrane protein 120A.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: CPSF6_CHICK
Sequence: MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDSLPPSVGDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPPSNRGRGRFPGAIPGGDRFPGPAGPGGPPHRSQLDKLPTRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPANSGIPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDAARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  Plays a role in mRNA export.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 6.
What is the protein family that this protein belongs to?
Belongs to the RRM CPSF6/7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PGTA_YEAST
Sequence: MHGIKRKQWTKELLRQKRVQDEKKIYDYRSLTENVLNMRDEKIYSIEALKKTSELLEKNPEFNAIWNYRRDIIASLASELEIPFWDKELVFVMMLLKDYPKVYWIWNHRLWVLKHYPTSSPKVWQTELAVVNKLLEQDARNYHGWHYRRIVVGNIESITNKSLDKEEFEYTTIKINNNISNYSAWHQRVQIISRMFQKGEVGNQKEYIRTEISYIINAMFTDAEDQSVWFYIKWFIKNDIVCKTLDEQEYLKMLKDLRENILLINNDEIEFSGKQNIWCLKILLVLEDILEEKEALTERSSEQYLVQLIDADPLRKNRYLHLLEQHK
What is the function of this protein?
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified.  Acts on YPT1 and SEC4.
What are the official names of this protein?
Geranylgeranyl transferase type-2 subunit alpha, GGTase-II-alpha, Geranylgeranyl transferase type II subunit alpha, PGGT, Type II protein geranyl-geranyltransferase subunit alpha, YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: CH10_CAUVN
Sequence: MKFRPLGDRVLVKRVEEETKTKGGIIIPDTAKEKPQEGEVVAVGPGARNDKGDVVALDVKAGDRILFGKWSGTEVKVDGQDLLIMKESDVLGVVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_BACCN
Sequence: MTLQEQIMKTLHVQSVIDPKTEIRKRIDFLKDYLRKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGSAKFIAVRLPYKVQKDEDDAQLALQFIKPDHSVSFDIAPAVDAFSNQYKDLLGESLTDFNKGNVKARVRMVTQYAIGGQQGLLVIGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRALLQELGSDKRLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKAVPQDVAKKIEKRYLASEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: ATG15_PASFU
Sequence: MIWNGRLVLACVLLIAGCSGQVDAARTREQRKAFGSPNIVLPPGPAHEVASAKPARALGEKTFTLRHVYHHGTHNYPNLHRYIDIQPESKLQVSYDDGTTYEEAEVAFKAKAQSRIVQRMAHRSHSDIDAVQVHYFTYGQPADVEWTEDEIAGPNISDKSTVLTFAKMAANAYIFSRKDGEWQPVKGGFNYTDDFGWEQDGLRGHIFADEANSTVVIGLKGTSPAIFDGADTTGNDKLNDNLFGSCCCAQGGPFTWKKVCDCAGSSAYTCNNTCLVKSLREKGHYYWAVKDLYRNVTERYPDSEVWLSGHSLGGVVSSLLGLTYGLPTLTFEAFPDAMAASRLGLPTPPGYKIGSHQARPMTGIHHFGHTADPIYMGSCNGGTSFCSIGGYAFEGVCHTGETCTYDTVRDLGWRVGIGTHKIVSVIKDVIKVYDQPPSCEQDVECVDCYNWKYFENNGTETTTSKASTATSTTTRTRTETCKTPGWWGCLDESTTSAPTTSTSTSSSTSSTRTCETPGWFGCKDETTTTSSSSSISSPSATPAPTITTTSSLPTSTSTSTCKTPGWFGCYDESTTTSATPKPSSTARTVTKTKTTTSDDDDCTSREWFGLICVDPSPTTASGSSPSSTNLPTTRRKMCTKRHWYGTCKQWRFDDFDPKNDL
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: Y2003_METTM
Sequence: MSLLGGMWKSTKPSRSKSPKPSSNPLRSSGLNSGMSSRLNSKSSLRSGHSRSSNTGRSSRQKSISGSLGSNPISSSRLNSKTLLSSIFMCKYLYPPWINNFGNFGRVEPPPLIEKNLKKSKKIKIKIHPWTGFPYNQVLSEKAKKYKKIRG
What are the official names of this protein?
Uncharacterized protein MTBMA_p00030.
Protein: FABZ_KORVE
Sequence: MAEAKQVLDVTDIQKILPHRYPLLLLDRIIEFKRKERIVAIKNVTINEQFFQGHFPGYPIMPGVLIVEAIAQAGGALLLTEIPDQNEKLMVFAGIEKAKFRKPVVPGDQVRLEVDVIVWRNTAAKLMGKAFVGDKLACEATVSCQIVPRPAKPENS
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AARP_PROST
Sequence: MYNKLPISYSRKHTQFQSSIISEILVWIEGNLTNRLSLDDIAQHSGYTKWHLQRVFRKIVGMPLGEYIRRRRICEAAKELQTTNLQVIDIALKYQFDSQQSFAKRFKAYLGISPSLYRLSDTGYNDLLLLEPKVA
What is the function of this protein?
Transcriptional activator of 2'-N-acetyltransferase.
What are the official names of this protein?
HTH-type transcriptional activator AarP.
Protein: EPG5_CAEBR
Sequence: MAELVRPKKPKHRERPQSDDAPRIPDRPVMVNGMRLPVAPSHSIQHQRDRSASPEPEEQVLSDTGESINPEKENGSIQDVRSSPVRPAPPPPRAISQEREAPPIPARNLVFPRSTSMVAESTREPTPVVLPKRSVAVAPYPTVPELAELPSYTAALKHPQVYPAVDGGQLHHSRSAAAIPEKTRFSAPVAQERVREGEAPPMYPSINTYERNEHGLMTEENLVTFYHNPLYEHAEIFVDQFIKAEVVPNQSGSLFPLLARLKSVCDLMTVSEVKGKENTEELQKCLRECWVQQTMSVEAKGKCGDNNDGTGRASYFSYELQQSVLDQMKRLLSTNRTNLLDHTLCEETSFRSLALQIQWQIIIINNNFMAENGLTTNCPPSLVATGPMTPGRTAIRTALSDIFYHLRYPRLSKRFIDTLFGWIKELTCILNMRQSCDDGIFLLCHLLRLPSPIDHWAPPFVQTFIQSQSPPRLKLDYCVALLTHLLNPIKARESFLRHVAQSEKEESTWEILADDDDGEANEFSFVTINESDLTAFLDQIPISELYSIAYLAFTSYSDKGSQFTAMIAFQLLLMKILDNGLTSYSQPGYKMFCKQIGISLKHSVRELCSNWRLIRDQIRPGEEQNLQKEVDRIVLLALNYLIHRDSVGLFQFVVALPYGVVSEECRSRCEYALRSNKKMSIHEIYETPICEVRARISSQSIAKRVSSLGAQDSEFLINSLASIGSYSNGDVGQLLKELIDVCFCEPATRDDFYKCGGEAIGQILTKRPETLHQLLAIVDRNLQHMDSYAINVLSSSRLFECRLTEPMISIIGKWLINNPPEHGANRLARRVLSGLHWGLGPDGQNLWIDVDVHAIAADTVVKAHSVHCSRSNSMISKSISKISKLASKVGDAESLFQQFCWDLLVKLKLPTIPVDLVQNDLTAHYVRIVQNYEDDVVVYLEKAVPLLSDLVSSGSSVASVVLLSRLIAQHYQKVNLMAADKNFMATFERLLHIDQLPYAVQWLSGPSSTPTPIVRLICSAISYYSAKLPPRDYLRAWITLLCQARTGWNEDAVTYQIVGTIARIAFINDTQKLYEITSIVFQAYQQQMAAEKNQSKGILALFSSDSSASPLIPDSMLAVSPFASYIMLRVEQKSFNPFYGHFYETLGKKDKYNLDHAAKKAASKCSMALPVERLAVFRWAKLVIVCKDSALLPIILQQLAGQAYRLRKANNLNLCYARRLIDEPQMQGVMAECRKAIEETTVATKGLSKAVVGWLFTKHEVTRTGFDFSVFDLDYLLQLILAGDKNMWMDFVNMPHFTSEEFAERKLYSVTCQLSPKNRESPSPPELGSPRARGTAKPFPVLPVHSGLPKAPCLDPSTIFQQHVVLQMAAPFMSTVKNLAKQYTECGDRMDIYDDAYCKLIRILYQSTQQTVPVEIRCSYCSKPKPCTMTVKPNVLSPEIDVKMSQNRQKRIEFWNELNASMIDQAAVATASMEHLSRLVSMMAAALDPRNRNSVQPTGHSLFYLITSSVGENELLFSVASESYSHSLRALGEEFVKFRPEEQMDVMQLALNGFVLSEPLVEVFTAEVLNSDDLCTAYRKLSDAVRMPERSKMALQLLGEQ
What is the function of this protein?
Involved in autophagy.  Has a role in the degradation of protein aggregates within autophagosomes.  Essential for starvation-induced autotrophy and omegasome development (By similarity).
What are the official names of this protein?
Ectopic P granules protein 5.
What is the protein family that this protein belongs to?
Belongs to the EPG5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2530_EDWI9
Sequence: MNIDVANLLTGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSMNTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVASALCIALGLGKLFRWDIGLTAGMLAGSMTSTPVLVGAGDTLRQTMADNPQLGQLQDHLSLGYALTYLVGLVSLIFGARYLPKLQHQDLPTSAQQIARERGLDNDTQRKVFLPVIRAYRVGPELVAWADGKNLRELGIYSQTGCYIERIRRNGILATPDGDAVLQVGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNSNAVSKRLSQVKLTDHGCFLNRVIRSQIEMPIDDNIVLNKGDVLQVSGDARRVKSVADRIGFISIHSQVTDLLAFCAFFIIGLMIGLITFQFTGFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGAGMRHGLGEVGGQMLIAGLIVSLVPVVICFLFGAFVLRMNRALLFGAIMGARTCAPAMDIINDASRSNIPALGYAGTYAIANVLLTLAGTLIIIVWPGVVG
What are the official names of this protein?
Putative transport protein NT01EI_2530.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3S1C_NAJKA
Sequence: LECHNQQSSQAPTTKTCSGETNCYKKWWSDHRGTIIERGCGCPKVKPGVNLNCCRTDRCNN
What is the function of this protein?
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.  Binds to the nicotinic acetylcholine receptor.
What are the official names of this protein?
Cobrotoxin-c, CBT-c, Short neurotoxin II, NT2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_SULAC
Sequence: MGKKLLQQRAGRGGINFRSPSWRRVGPARYPNIEGDHKGKIIDILHNPGVTAPVVKVKLDNGLQFYIPAVQGVAVGQEISIGKNATISNGNIVEVGQLPEGTVICNVEKLKGDGGKFARAAGSYAVISGKAGNKVLIKLSSEKIVEVSQNARATVGIIAGGGFVEKPLLKAGNNYWKYRVRAVKWPVVRGVAMNAVSHPHGGGLHQSVSRPSTVSRNAPPGRKVGHIASRRTGRRGGA
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RIBB_SALSV
Sequence: MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: YBEY_VIBVU
Sequence: MAIELDLQLAVEDQNGLPSAQDFQTWLDKTIPPFQPQAEVTIRIVDSQESHQLNHDYRGKDKPTNVLSFPFEAPPGMEMDLLGDLVICRQVVEQEAIDQDKPLMAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETEIMQGMGFTDPYLAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_STAA3
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_MYCSK
Sequence: MDLVIGRVAKAHGVTGELVVEVRTDDPDARFVPGARLRGRAPRGGAERAFVVESVRPHGGRLLLRLDGVADRTAADALRGTVFLVDSADLPPIEEPDEYYDHQLEGLLVRTVDGVDVGTVAEVLHTAAGELLSVKTPEGAEILVPFVTAIVPRVSLADGLVEIDPPEGLLDLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_AZOVD
Sequence: MLELDLQVASVRPLPAEDDFRRWCELALRQRSADSELTIRLVDEEEGRELNRTWRHKDYPTNVLSFPAEVPEGLLDIPLLGDLVICVPVVEREAAEQDKAADAHWAHLVIHGCLHLLGYDHIEDAEAEEMESLERDLLAELGYPDPYDGDDLPEPGTMSEGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2790_SULIL
Sequence: MKIKDAVNMIRWEYREKIDDYVIIIIDRLTENGLKEISFSELDAVDNNYLYLKSEENTVIPLHRVLMIKRKSDNALIWKR
What are the official names of this protein?
UPF0248 protein LS215_2790.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: MOAC_DESRM
Sequence: MSELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARVAGIMAAKSTPNLIPMAHPIMITGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSVAALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGESQWEK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: VE6_BPV2
Sequence: MDLQSFSRGNPFSGLACVWCREPLTEVDAFRCMIKDFHVVYRDGVKFGACTTCLENCLDKERRLWKGVPVTGEEAQLLHGKSLDRLCIRCCYCGGKLTKNEKQRHVLYNEPFCKTRSNIIRGRCYDCCRHGSRSNYP
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MIAB_ECOSE
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRMAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDRD7_XENLA
Sequence: MLRAVLQANKNGVPLHKLQAEYKSVTGEPIPFKDMGFPALDAYLKSIPSVVRIEVSRVGEVTCYAVACKETARIAELVAHQRSSKKKGGHQVNCQMRLKSTAPVSHFGKPKITLRQPGFTPPQEMMIRKPVPTPPWGKGNYFGPRTFEYSPQPIPQLFGVAPMQRHLPNMNRPERKVTLPPRFQREVKSPLLPTPITDSNANHTQSYKRVVIGSGQSDLPVIQNNLKELLNKHSNGLWLSKLPQLYKETYKQDLGGEVLKQVPSWTHICTVQKLVSSGHTEIVIYATTRKQQPSTKNIQNRSNDQAKPNVPVVLSTPSSPPPLQISGSIPKDELKEKISTILTKYSNGLWYHALPKVFEDMFKQKLPIEAFNLDSLTDICTVDLISEEPFKAILYGKSAERAVQNSNPSVNNNIPQKLHDREPPLCSEEPDMTMAPPPLVIPSEASPSVLVVELNSTNDVVIRYIGRDYSAAQERMEDELKDFCSKSSTAQVRPLRVGQLVAAKAEEDAWLRAQISAIEDKKIKVCYVDYGFSETVDITKVCKLGKPFYTLPFQATKCRLAGLEAFCDDSVIIKALEAKACGKILAVEILHKSEKPLVVLYDTSGDDDININAACLKELYDRSLSLQLKANLSFSNVTVTNVCSDGTLFCQVPSKGLAKLYETLQKVDGEFQFQQVTSHLYVSLPFCGKICLYHYKGKWARVEITNVHSSRALDVHFLDSGTIASVKVSELKEIPPPLLRDLISIPPQALKCCLADLPLNIGMWTPDAVLWLRNTVLNCPECSIKVVKIDEAMNMVHIYLFTSNNFPDLERSINRRITNEELLKQKQKDVFLNMSVSSLEKGRGGGGAPASQLFPSGPCISPTSVAKKPDMQQSSPVPSFNMPPALPLPRPGEHMDVFVSVACHPGHFVCQPWQELHKLELVMDEMRLHYSTTEEKPIALEKNKLYAAKIENNWYRVLVKGILTNGLVSVYELDHGRHELVSCRKVQPLIEKFMHLPFQAITSQLAGINCEQWSEETSIVFRNHVEKKPLVALVQTIHESTHPWERRVVAYIVDTTLPDTDIWIHELMTEYLAQFSKPE
What is the function of this protein?
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation.  Probably required during spermatogenesis (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the TDRD7 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cytoplasmic RNA granules.