PharMolix/UniProtQA huggingface dataset:
Protein: FHKE_DICDI
Sequence: MDELTQANTLAIDEDLVDSVNSVKGWGILKSLNPSYPDISLVENVITFGRLKDSTVHYNDKSISGSHCKITRESNDDDGVVIAFIYDNSTNGTFIDNIKVGKGSRCLLASGQEISLTPQKQLEKIAYIFQTVEKEIEDGGPSNKYFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILELVECGELLNDIVSNLFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTSSGGHNGYGLEVDCWSMGAILYIMLCGYPPFDDSREVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWFNPNVKLSTLLEEDERLRKKAEAEVEANNNNTNKSNSPKMLGKRKSEDGNCSDSNNNNNSGSKSLSSIKSNTTMLDCDEKSNNNNNNGHKKSKSDPTSNNSLFNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNDTTDSDTDDETISLPVITKNSKSMSNLQNHLNNNKINSDDESETSTNNNNNNNNNNNNNNNNNNNNNNNNKPSTINNNFPVPFPKSPTKNSPNASPPIKPQNSSNNNSGLAGIDKPKCQYDPNCYRKNPQHLRDFYHTVSSNK
What are the official names of this protein?
Probable serine/threonine-protein kinase fhkE, Forkhead-associated kinase protein E.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHK2 subfamily.
Protein: NADE_AGRRK
Sequence: MNPSPLSIHSALSSDALRIDAAAEVDRIAQAMRDQVRNKMRRRGLVIGLSGGVDSSVCAALAAYALGAQNVFAIFMPENDSDPESLSLGQEVAKAFSLEGAIEDIGSALAAMGCYERRDDFIRQVEPAYGSGWSCKVVISSPLAGEGYALSTLVLQAPDGSQTRHRMPASVYLGIVAATNMKQRTRKQMEYYHADRLNYAVLGTPNRLEYDQGFFVKNGDGAADLKPIAHLYKSQVYQIAEYLGVPEEVRRRPPTTDTWSLTQTQEEFYFALPYDRMDLCLHALNEGLGVEETAKATQLTTDQVERVWLDIHSKRKATRPLHLAPLLVQPVF
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: MATK_HORJU
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIVSCNNKKFSSLLVKRLIIRMYQQNFLDNSVNNPNQDRLLDYKNYFYSEFYSQILSEGFAIVVEIPFSLRELSCPKEKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFYFQKENKRLFKFLYNSYVSEYEFFLLFLRKQSSCLPLASSGTFLERIHFSRKMEHFGIMYPGFSRKTLWFFMDPLMHYVRYQGKAILASKGSFFLKKKWKCYLINFWQYYFFFWTQPRRIHINQLANSCFDFMGYLSSVPKSPLLVRNQMLENSFLIDTRMKKFDTIVPATLLIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEEQVFSLMFTKTTLFSFCGSHTERIWYLDIIRINDLVNPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SURE_HELPG
Sequence: MKKILLTNDDGYHAKGIKALEQALEEMAEIYVVAPKHEKSACSQCITITAPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFKNGYPLKGRKLLNVNVPNCSLQEYKGERITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLEWQKRENEDRLSDFDAIASNHASITPLNLDLTSYDDLKSLESWHEGMLK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGA_PSEFS
Sequence: MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIEVRLEARGLTPTYHEGMRITDAATLECVIDAVGHLRIAIEARLSMDMASSPMQGSRLRVTSGNFVTARPIGVLEGVDYHHTGEVRRVDRKGINRLLDERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGADLGLIDENGRLVRELRPQQVPAHLQRLGSSNYQAELLDAAAEACRGGVGRSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLLDLISPLEEQGILVRRSREVLEREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNPEYRHGARGDVLLERIQTRARAQGLKTLFVLTTRTAHWFRERGFVPSSVDRLPSARASLYNYQRNSKIFEKAL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAM5_DROAN
Sequence: MRKLSSLVCGAGAGLAAFYLSRLRDPQKAAHSSWTNSEKPVDACGLWDSNWDCRDPRLMVRPLKNTQPEEENRFNADLEKAKPKKARHIILVRHGEYLDVGESDATHHLTERGRKQAQFTGQRLSELGIQWDKVIASTMVRAQETADIILKEIKYDKEKVVNCVYLREGAPIPPQPPVGHWKPEASQFYRDGARIEAAFRRYFHRAYPDQDKESYTLIVGHGNVIRYFVCRALQFPPEGWLRISINHASITWLTISPSGNVSIKYLGDSGFMPVQYLTNRIPRDAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PDXJ_YERPS
Sequence: MADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTIQTRMNLEMAVTDEMVDIACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVVGRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYADASTVLERQAELMRIAKAATYAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMREARR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSY_BOVIN
Sequence: MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMTESVHTWQDHGYLATYINKNGSFANLRIYPHGLVLLDLQSYDGDAQGKEVDSLLNKVEERMKELSQDSTERVKRLPPIVRGGAIDRYWPTADGRLVEYDIDKVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKEDYSGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKAKP
What is the function of this protein?
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
What are the official names of this protein?
Spermine synthase, SPMSY, Spermidine aminopropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
Protein: UBIG_XANCB
Sequence: MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVLDVGCGGGLLSEAMARLGAQVTAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPGSFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLNRTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MNHB2_STAS1
Sequence: MKENDVVLKTVTKIVVFILLTFGFYLFLAGHNNPGGGFIGGLVFSSAFLLMFLAFDVKQVLVALPLDFRILMICGSLLSFLTAVVPMFFGKPFLYQTDAYVQLPLLGEVHLTTVTVFEAGIVLAVVGVVVTVMLSISGGRS
What are the official names of this protein?
Putative antiporter subunit mnhB2, Mrp complex subunit B2, Putative NADH-ubiquinone oxidoreductase subunit mnhB2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEPA_ECO81
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPALWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PLSY_PROA2
Sequence: MLTLIVILAVSYLIGSIPTSIIAGKLLRGIDVRDYGSGNAGGTNAFRVLGWKAGLAVTLLDIVKGAVAAISVVVFFEAHPLGAMPDINPVALRLIAGLAAVFGHVFTVFAGFRGGKGVSTAAGMMFGIAPVSTLIVLAVFLLTIFVSRYVSVASIIAAIAFPLVILVRKYLFDLGEGLDYYIRMFNGHVFIHDSLDFHLLIFGMIVAFAIIYTHRANIGRLLSGNENRVTFGRHA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXC_ECOLU
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: FDL_DROME
Sequence: MSLAVSLRRALLVLLTGAIFILTVLYWNQGVTKAQAYNEALERPHSHHDASGFPIPVEKSWTYKCENDRCMRVGHHGKSAKRVSFISCSMTCGDVNIWPHPTQKFLLSSQTHSFSVEDVQLHVDTAHREVRKQLQLAFDWFLKDLRLIQRLDYVGSSSEPTVSESSSKSRHHADLEPAATLFGATFGVKKAGDLTSVQVKISVLKSGDLNFSLDNDETYQLSTQTEGHRLQVEIIANSYFGARHGLSTLQQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDTSRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHGAYSESETYSEQDVREVAEFAKIYGVQVIPEIDAPAHAGNGWDWGPKRGMGELAMCINQQPWSFYCGEPPCGQLNPKNNYTYLILQRIYEELLQHTGPTDFFHLGGDEVNLDCWAQYFNDTDLRGLWCDFMLQAMARLKLANNGVAPKHVAVWSSALTNTKCLPNSQFTVQVWGGSTWQENYDLLDNGYNVIFSHVDAWYLDCGFGSWRATGDAACAPYRTWQNVYKHRPWERMRLDKKRKKQVLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDMDIVPPDVFRRISLFRNRLVELGIRAEALFPKYCAQNPGECI
What is the function of this protein?
Involved in brain restructurization via hormonal control during metamorphosis.  Implicated in N-glycan processing.
What are the official names of this protein?
Probable beta-hexosaminidase fdl, Protein fused lobes.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
Protein: NEP_INBLE
Sequence: MADNMTTTQIEWRMKKMAIGSSTHSSSVLMKDIQSQFEQLKLRWESYPNLVKSTDYHQKRETIRLATEELYLLSKRIDDSILFHKTVIANSSIIADMIVSLSLLETLYEMKDVVEVYSRQCL
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: VBP2_ASCSS
Sequence: MSKVIFALVLVVVLVACINATYVEFEEAYAPVDCKGQCTTPCEPLTACKEKCAESCETSADKKTCRRNCKKADCEPQDKVCDACRMKCHKACRAANCASECPKHEHKSDTCRACMKTNCK
What is the function of this protein?
Acts as a vanadium reductase which may form an electron transfer cascade in conjunction with NADPH and glutathione through thiol disulfide exchange reactions.  Partial cleavage of its disulfide bonds results in the reduction of V(5+) to V(4+).  Binds up to 24 V(4+) ions per protein at pH 7. 5.  Also binds Fe(3+) and Cu(2+) and, to a lesser extent, Co(2+), Zn(2+) and Ni(2+).
What are the official names of this protein?
Vanadium-binding protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_FRATH
Sequence: MLTFQEIILKLHHYWASKGCAIVQPLDMEVGAGTFHPATTLRAIGPEPWTAAYVQPSRRPTDGRYGENPNRTQHYYQYQVVMKPSPDDIQELYLGSLRELGIDPLENDIRFVEDNWESPTLGAWGLGWEVWSNGMEITQFTYFQQVGGLECKPVMGEITYGLERLAMYIQNVDSMYDILWANTQNGPLYYRDVFLQNEVEMSTYNFEEANVEELFKQFDLLEKEGYRLVEKNLPIPAYEFVLKASHTFNLLDARHAISVTERQGYILRVRKLALEVAKEYYSAREKSGFPAFKKDN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_MYCTO
Sequence: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ACTP2
Sequence: MARVTVQEAADKIGNRFDLILTAARRARQLQLHAREPLVPEENDKPTVIALREIEKGLINGQIMDQLENNDAIQQEVAEQEAISFLADVQG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DAF25_CAEEL
Sequence: MTTTEEAPKSPLFEAIDKNDTEAALALLKTKEQAAQRDPSGMSVLAAAAYRGNLTLVEKAIELKCDVNDKTDGTLYTPLMFAALSGKQDVCRLLMDSGARMYLVNGIGKTASELAAFVGHHECVAIINNHITIDVIEDLLRPKVNGKYEGAEEYPDELAVFIHSLCGSHEIHPVKIIFRFSKYPDSLKYKKKILYVIDRVFEKQLRCKESNEIMSLKLWLILFSMRETSKFVESNKEKSPEEASLQYAKLISTWQEGDETRRALDVMLRNAVASFPYKHSLLHDTLQKALQKSQIGERPSAYEYIVQALFGQRIAAVCQFCSVCGHPGAKKRCTQCKLAYCSQECQKFDWPIHKKVCSFLKTRQEVSPTDETAMSLDDIQAQIAKIDV
What is the function of this protein?
May be involved in the trafficking and dendritic transport of signaling proteins, such as the receptor-type guanylate cyclases gcy-12 and daf-11, to the cilia.  In ciliated sensory neurons, required for the calcium flux to the cytoplasm in response to onset and removal of a nitric oxide (NO) stimulus and is thereby required for the behavioral avoidance response to NO-producing organisms like P. aeruginosa (PubMed:30014846).
What are the official names of this protein?
Dauer abnormal formation protein 25, daf-25, suppressor of che-2 small body size 3, Chb-3.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: RISB_EXIS2
Sequence: MVFEGFLTGEGLRVAIVAARFNELITSKLVGGANDAFRRHGVAADAVDTAWVPGAFEIPLVAEKLAKSGNYDAVITLGAVIRGATSHYDYVCNEVAKGVAGASRETGVPIIFGVLTTDSIEQAVERAGTKAGNKGYEAAVSAIEMANLLRTI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PTH_AGRRK
Sequence: MLLIVGLGNPGAKYQGNRHNIGFMAVDAIHRRHSFSPWAKKFRAEISEGELGGQKVLLIKPQTFMNLSGESVGEAMRFYKLEPSDLVVIYDELDLPAAKARLKTGGGHGGHNGIKSIDAHCGREYRRLRLGIGHPGVKELVQNHVLGDFAKVDRDWLEPLFDALADNADMLVRGEDSQLMNKIALALGGKTEEPAPKPEKKTVAKSHIHQARNHNQPRMPESGPMAEMLKRMFGKKDD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_SALTI
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNTFCGADAPQLRFEVGTKPVTQTLKTPVHNVVAPTQTTTAQPQRVAPAARSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKIADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METPP
Sequence: MKVYYDKDADLSLIKGKSVAIIGYGSQGHAHAQNLNDSGVKVTVGLRRGGASWNKVEKAGLKVAEVADAVKSADVVMILLPDEQIASVYSAEVAPNIKQGASLAFAHGFNVHYGQVVPREDLDVWMVAPKAPGHTVRNTYTQGGGVPHLIAVHADKTGKARDLALSYAAANGGGKAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEDTKAAMRQCLKDIQTGEYAKSFILENRAGAPTLLSRRRLTAEHDIEVVGEKLRAMMPWIKANKLVDKSRN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ARAA_ECOSM
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: RTCA_PSEAB
Sequence: MRKDLIELDGSEGGGQILRSALSLSMTSGQPLRIRNIRGRRSRPGLLRQHLTAVRAAAEICAAEVEGAELGSRELAFRPGAIRAGDYAFAIGSAGSCSLVLQTLLPALLAANGESRVRISGGTHNPLAPPADFLRDSWLPLLQRMGAEVDLELLRHGFVPAGGGELLARVRPARWRPLQLEHPGAALRRQARALLAGIPGHVGERELERVRQRLGWSDEERQLEFLAEDQGPGNALLLRIDCEHICATFCAFGQAGVSAERVAEQVATQAIGWMESGCAADEHLADQLLLPMALAGAGSFTTPRLSAHLQSNRRVIERFLPVRIGDQALDGGGHRIVITSA
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP_GEOSL
Sequence: MEQVIGVIGGSGLYEMEGLQDVRSIVVETPFGAPSDEFVTGVLDGVRMVFLPRHGRGHRLLPTEVNYRANIYGMKKLGVTRIISVSAVGSMREEIVPGHIVIPDQFIDRTNATRANTFFGNGVVAHIQFADPVCADLSADLYAAAQEAGATVHRGGTYICMEGPAFSTRAESNLYRSFGVSVIGMTNIPEAKLAREAEICYGVIALATDYDCWHESHDDVSVDAIIAIIKQNVAMAKSIIRNAVRRIDRERNCPCASALRYAIITDKAAIPAETKERLDLIIGSYV
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: RS8_YERPB
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGFIEDFKIEGDTKPVLELALKYFQGKAVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.