PharMolix/UniProtQA huggingface dataset:
Protein: M1_I96A0
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDNLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: TPS2_COFAR
Sequence: EVEEPKTKISASTAEASSSRISSAKMTADGTIKLGDQSPLKQSEKDHPVSWDFKLVQSLRNEYADERYISRSAMLDQEMNVVNLLELIDNLQRLGLSYHFEDKIRSILSGIYNTIKMRNPEGLYATALEFRLRRQHGFYVPQEIFESFKDENGDFNHSLCEDLKGLLYLYEASYLEKENESNLEMAREFTAKHLKKILKEKRIDQELEALVQHALELPLHWRMMRLEARWFIDIYEARSDRNPILLELAKLDFNIVQAIHQNDLECTLRWWSSTGLAEKLSFARDIMVENFFWTVGTISDPQHGNARRLLTKVAALVTAIDDVYDQYGTEDELELFTSVVERWDVNSIDQLPDYMKICFLALFNFVNEMAYDALKEEGVNIIPYLRKAWADLCKAYLQEAKWFFSGHIPTLQQYLNNAWTSISAPLVVVHAYFCVDYPINKDHVEYLEKCHKIIRCSSMIIRLANDLGTSPESEVLKSADVPKSIQCYVKETGACEEKAREYLRFLIIEAWKQMNEAQTVDSPFSSTFKGFAVNVARMGQCMYQHGDGHAHQNSEPRDRILSLLFEPISSFA
What is the function of this protein?
Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpenes natural products, constituent of coffee beverage aroma (PubMed:23398891).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into linalool and beta-myrcene, and, as minor products, cis-ocimene and trans-ocimene (PubMed:23398891).  Not able to use geranylgeranyl pyrophosphate (GGPP) and farnesyl pyrophosphate (FPP) as substrates (PubMed:23398891).
What are the official names of this protein?
Linalool synthase TPS2, chloroplastic, Cis-ocimene synthase TPS2, chloroplastic, Myrcene synthase TPS2, chloroplastic, Trans-ocimene synthase TPS2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KDSB_ECO57
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKGLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYGEKIHVAVAHEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UAP1_SCHPO
Sequence: MDDKELFDRSIFEETNQLHLYDQLNYLKKNDLQKFRKLLNQVQQLDLRSLWLKYRNAKATSQENRKLSPSEVGPLSIVDTSDSSWWRTGLREIARGHVAALVLAGGQGTRLGFAGPKGCFRLGLPNNPSIFELQAQKIKKSLALARAAFPDQEASISIPWYIMVSECTSEETISFFKENDFFGIDKKDVFFFQQGVLPCLDISGRVLFESDSSLAWAPNGNGGIYEALLSSGALNDMNRRGILHITAYSVDNVLVLPVDPVFIGMATTKKLEVATKTVEKIDPAEKVGLLVSSHNHPCVVEYSEISDEACKATENVDGHKHLLLRAANIAYHYFSFDFLQKASLHSSTLPIHLACKKIPFYDVTSHHYTTPLNPNGYKLESFIFDLFPSVSVENFGCFQVPRRTSFSPLKNSSKSPNDNHETCVNDILSLGKSWILKNGGILSPSDCTYVSPECSLQGESLEWIKGKQVSNCKLY
What are the official names of this protein?
Probable UDP-N-acetylglucosamine pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL20_HAEDU
Sequence: MARVKRGVIARARHKKILKAAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSKFINGLKKASVEIDRKTLADIAVFDKVAFAALVEKAKSAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MOC2B_NEOFI
Sequence: MTTQPPQDQTSTTPSLPPHLDPTTYPRTLTSATHNIHLELTYSTLNPTVALEHTSSPAAGANVLFLGTTRNTFEGRAVSQLSYTSYPPLALKSLMSIATRAAEKFDLKGVYIAHRLGVVPISEASIVVAVSAGHRGMAWKAGEEVLEEVKEKVEIWKREEFVDGGMEWRENRERDAEGRLLSSTEGGK
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Common component for nitrate reductase and xanthine dehydrogenase protein H, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSG3_DICDI
Sequence: MNKLILSILSVLLIVSIASAGNGIDISSGTNPSSSDLACLAKQNSKIIVQTWSGGYGFNSNVPSIVQAAKSAGLSVDLYAFLCSQCSGITDPAEAIKTLVSKLNGVKYGTLWIDVEQCNGCWSSTLSSNAQYVQTAVQTASQLGVNVGVYSSEGEWPQTVGSLTSLSSFPLWYAHYDNNPSFSDQGYNFGGWSKAVMKQYQGTTTQCGVSVDLNWFPGSGSSTTSSSATSSSTTGRPLTSSSGAGTGGHSSSSGAGTGGHSSTTGGQTSGQTSGQTSGSSNQPLSSGSSQDSSNSGSSNQPLSSGSSQDSSNSGSSNQPLSSGSSQTSGQTSGSSNQPLSSGSSQDSGSNSGSQGTTGSQSGSSSSNPLTSGSQSGSSGSQSTSSGSQSGSSGATGTSSTASSTSATGSSSTGSSTGSSSGSNDSGSNDSGSSSGSNNSGSSSGSNNSGSSSGSASSSGSSGSSGSGNYTSGSGNGAFLF
What are the official names of this protein?
Probable GH family 25 lysozyme 3, 1,4-beta-N-acetylmuramidase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNG2_HUMAN
Sequence: MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAITFSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASVDNYQQPPFTQNAETTEGYQPPPVY
What is the function of this protein?
(Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.
What are the official names of this protein?
Synaptogyrin-2, Cellugyrin.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes. SUBCELLULAR LOCATION: Lipid droplet. Note=(Microbial infection) Upon SFTS phlebovirus infection, the protein localizes in lipid droplets and inclusion bodies.
Protein: CTNL_DICDI
Sequence: MNKSLFSLILLIITIFNLASNINIVSAISNFNINNNNKNNNDNKEIRFPTDIIIDDSTEINFNNHEDNNNNNNNNNNNNNAYNEDSGNSVQLGDIECVVCLDFLDSYLPTLVKIISEYGVIESCSKICGLLNKTDEIDICTGLCDLVGVDTFWKIFVTNDINPFYACELITACSTPKNPAADFISLGVSPAIGQSGSKFLIDLTFQVVNTTGAGQFAFIVFYTQTQSKFINYQLFEGFSPGNYSVKYDFETTNNSTFINGQYPVTVYMCNGECGTMYSTLLNQTTSYFTISNPTPTPTPTPSNSTTPTPTPTNSTPTPTSTSTPTSTPTSTPTPTPTSSSSTKTHSSHYKNKINK
What are the official names of this protein?
Countin-like protein.
What is the protein family that this protein belongs to?
Belongs to the countin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_NITEC
Sequence: MSVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHLGRPEEGVWAMENSLQPVANDISRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEKKNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAPVACAGILLTEELDALTKALHQPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELVPIAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQELVNIIMKAGTVVWNGPVGVFEFDQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYDKVSYISTAGGAFLEFLEGKKLPAVEILELRAQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_SALPK
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQHGIFPWFSPGDPILWWSPDPRAVLWPEKFHLSRSMKRFHNASPYRVTLNYAFDRVIDGCANHRDEGTWITRGIEEAYRRLHELGHAHSIEVWRDQELVGGMYGVSQGALFCGESMFSRQENASKTALLVFCAEFIRHGGKLIDCQVLNSHTASLGAIEIPRRDYLDHLAGLRQQPLASRFWVPRTLFLPRK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CAMJE
Sequence: MPKMKSVKSAVKRFKVGKNKIKRGSAFRSHILTKKPAKRMRGLRTAKYVHSTNVKAVEKMLGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL19_RICCK
Sequence: MNIIDSFEQKNIAKLTANKNIPDFEAGDTVKVTVKIIDRSIEKDGKEKLTERFQAYEGVVIAKRNRGITSSFLVRKISHGEGVERRFMTYSPIVHSIDVVKYGVVRRAKLYYLRNRSGKSARIKERHIPIAKNQAVKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CTHL4_BOVIN
Sequence: MQTQRASLSLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDQLNELSSEANLYRLLELDPPPKDNEDLGTRKPVSFTVKETVCPRTIQQPAEQCDFKEKGRVKQCVGTVTLDPSNDQFDLNCNELQSVILPWKWPWWPWRRG
What is the function of this protein?
Potent microbicidal activity; active against S. aureus and E. coli.
What are the official names of this protein?
Cathelicidin-4, Indolicidin.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSF3_DEBHA
Sequence: MTSNYFDLDDILSDGEKIPCRFNITVPGLGYLEGNPGKSIAKDTKIELPLWLAEILAICELSEDSQQSFIDLSQPDFINYKVINAIKTNAVNIDLHSILTNYYKLSEKWASMFNDVELIEVVMQMLKERSFEINNYASNASKQINNNFIFSLDEFEKKLFKVTSDSNKQMRKWLKD
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein PSF3.
What is the protein family that this protein belongs to?
Belongs to the GINS3/PSF3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSH_SLAHD
Sequence: MSETPNTNEQNNPNNQQDGTGQNPMPPMPTGKPQMPERPERHNQADGAPKRPGDDDRKSERPTWLSEFSDKEEDFASRLNTRPPQRASIITIIIIFLVAFFIGSQMMNMVHGEETDDLTTSEFVQAVEQGRVENVVYNAGEYTVTGKYYPAATAGSTIAESYNSAIESVDVKLGTILEPSNPSSVGIETTSLEEKTLGTERNYTATYVGQDSLMELLSAHPEVEYQVTLPSNVTEILISVLPMLLFAGLLIYFFSQMSKANNSQMSFGKAKAKKTTEERPDVRFSDVAGEDEAVEELQEIKDFLVNPGKYQKLGAKIPRGCLLVGPPGTGKTLLARAVAGEANVPFFSISGSEFVEMFVGVGASRVRNLFEQAKEAAPSIIFIDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGFEKNDAVVLIAATNRVDVLDPALLRPGRFDRQIVVDGPDVKGRVKILEVHAKNKPIGEDVDLERIAKLTSGMTGADLMNLMNEAALLTARRNKDKIGMDEVNESMERLMAGPERKTRVLNEKTRRTIAYHESGHALVGHMLENADPVHKITIVPRGMALGYTMSIPDEDKFLVSRSAMLDELAVFMGGRVAEEIFCGDITTGASNDLERATKTARKMVVSYGMSEALGQQTFGQPNHEVFLGRDYGNTQDYSPETAQRIDEEVARLMKEAHDTAYEILSARQEQMHTMAKVLLERETVDGEECQALLNNTWDEFLAKKQAEAAAKAADQAEQPQVEAEPVAQVATPAAPVAPAVPEAPQPPAAPQQ
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RL34_STRA1
Sequence: MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: UCRI_SCHPO
Sequence: MLAKQFISKSLASSLRRLLPVSSTASSLKGSMMTIPKFTSIRTYTDSPEMPDFSEYQTKSTGDRSRVISYAMVGTMGALTAAGAQATVHDFLASWSASADVLAMSKAEVDLSKIPEGKNLVVKWQGKPVFIRHRTPEEIQEANSVDISTLRDPQADSDRVQKPEWLVMIGVCTHLGCVPIGEAGDYGGWFCPCHGSHYDISGRIRRGPAPLNLAIPAYTFEGSKIIIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster.  It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0) site in cytochrome b to cytochrome c1.
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Rieske iron-sulfur protein, RISP, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CARL1_MOUSE
Sequence: MTDESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRAFLLSARIPSKLELTFSYLEIHGVICHKPAQMVVETEKCNMSMKMVSPEDVSEVLAHIGTCLRRIFPGLSPLRIMKKVSMEPSERLASLQALWDSQTLAEPGPCGGFSQMYACVCDWLGFSYKEEVQWDVDTIYLTQDTRELNLQDFSHLEHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLAGALAHNPNSGLHTINLAGNSLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNALRGDDLSHMYNFLAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSVFSHRKGKEVPPSFKQFFSSSLALIQINLSGTKLSPEPLKALLLGLACNHSLKGVSLDLSNCELGHCLRSGGAQVLEGCIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEDSPLQSLSLADSKLKAEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDAAQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRACGGDAIQEDLKAAERLMRDAKNSKTLLPNLYHVGGASWAGASGLSSSPIQETLESMAGEVTRVVDEQLKDLLESMVDAAETLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDSLSSSHRKLANHFSRLNKSLPQREDLEVELVEEKPVKRAILTVEDLTEVERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSVRQEKRSSGLISELPSEEGRRLEHFTKLRPKRNKKQQPTQAAVCTISILPQDGEQNGLMGRVDEGVDEFFTKKVTKMDCKRSSSRSSDAHELGEGDEKKKRDSRRSGFLNLIKSRSRSERPPTVLMTEELSSPKGAMRSPPVDTTRKEIKAAEHNGAPDRTEEIKTPEPLEEGPAEEAGRAERSDSRGSPQGGRRYVQVMGSGLLAEMKAKQERRAACAQKKLGNDVISQDPSSPVSCNTERLEGGATVPKLQPGLPEARFGSGTPEKNAKAEPRVDGGCRSRSSSSMPTSPKPLLQSPKPSPSARPSIPQKPRTASRPEDTPDSPSGPSSPKVALLPPILKKVSSDKERDGQNSSQSSPRSFSQEASRRSWGPAQEYQEQKQRSSGKDGHQGSKCSDSGEEAEKEFIFV
What is the function of this protein?
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments.  Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028).  Plays a role in lamellipodial protrusion formations and cell migration (PubMed:16054028).
What are the official names of this protein?
F-actin-uncapping protein LRRC16A, CARMIL homolog, Capping protein regulator and myosin 1 linker protein 1, Capping protein, Arp2/3 and myosin-I linker homolog 1, Capping protein, Arp2/3 and myosin-I linker protein 1, CARML1, Leucine-rich repeat-containing protein 16A.
What is the protein family that this protein belongs to?
Belongs to the CARMIL family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane. Cell projection, lamellipodium. Note=Found on macropinosomes (By similarity). Colocalized with heterodimeric capping protein (CP) and F- actin in lamellipodia but not with F-actin in stress fibers (PubMed:16054028).
Protein: Y3034_MYCTU
Sequence: MNVLSLGSSSGVVWGRVPITAPAGAATGVTSRADAHSQMRRYAQTGPTAKLSSAPMTTMWGAPLHRRWRGSRLRDPRQAKFLTLASLKWVLANRAYTPWYLVRYWRLLRFKLANPHIITRGMVFLGKGVEIHATPELAQLEIGRWVHIGDKNTIRAHEGSLRFGDKVVLGRDNVINTYLDIEIGDSVLMADWCYICDFDHRMDDITLPIKDQGIIKSPVRIGPDTWIGVKVSVLRGTTIGRGCVLGSHAVVRGAIPDYSIAVGAPAKVVKNRQLSWEASAAQRAELAAALADIERKKAAR
What is the function of this protein?
Regulates host peroxisome homeostasis in response to intracellular redox levels to favor mycobacterial infection in macrophage (PubMed:32388919).  Induces the expression of host peroxisome biogenesis and proliferation factors as well as peroxisome associated enzymes.  Inhibits the induction of host pexophagy mechanism by down-regulating the expression of pexophagy associated proteins and adapter molecules in infected macrophages.  However, during increased oxidative stress conditions, it induces degradation of dysfunctional and damaged peroxisomes.  Regulation of peroxisome biogenesis and degradation is dependent upon host p-mTORC1 mediated signaling pathway (PubMed:32388919).
What are the official names of this protein?
Probable acetyltransferase Rv3034c, Peroxisome homeostasis protein Rv3034c.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: MTGA_BRUME
Sequence: MWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMVKDYALLQGVNRQWVDIENIAPVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSRGASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSRKRIMEIYLNIAEWGPGIYGIEAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYVTCVK
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YTJA_SALPC
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ODPA2_ORYSJ
Sequence: MAAAVVLLRRLRGVTAAPRRAAAALPLTTSVRGVSDSTEPLTIETSVPYKSHIVDPPPREVATTARELATFFRDMSAMRRAEIAADSLYKAKLIRGFCHLYDGQEAVAVGMEAATTRADAIITAYRDHCAYLARGGDLAALFAELMGRRGGCSRGKGGSMHLYKKDANFYGGHGIVGAQVPLGCGLAFAQRYRKEAAVTFDLYGDGAANQGQLFEALNMAALWKLPVVLVCENNHYGMGTAEWRASKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKQHALENGPIILEMDTYRYHGHSMSDPGSTYRTRDEIAGIRQERDPIERVRKLLLAHDFATTQELKDMEKEIRKQVDTAIAKAKESPMPDPSELFTNVYVNDCGLESFGVDRKVVRTVLP
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PAL1_NARPS
Sequence: MACANGNGNANGLCIRDPLSWGAAAEALAGSHLEEVKRMVKEHREACIRLGGATLKVGQIAAVANGGSAAKVELDESARARVKASSDWVMDSMSKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGSGRDSCNTLPASTTRAAMLVRINTLLQGYSGIRFEILEAITRLLNNNVTPCLPLRGTITASGDLVPLSYIAGILTGRPNSKATAPDGAQIDASEAFRLAGITDGFFQLQPKEGLALVNGTAVGSGLASTVLYDANILAVLSEVFSAIFCEVMQGKPEFTDHLTHKLKHHPGQIEAAAVMEHILDGSSYMKMAKKLHELDPLQKPKQDRYALRTSPQWLGPQIEVIRSATKSIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLAIASIGKLMFAQFSELVNDFYNNGLPSNLSGGRDPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISARKTEEAVHILKLMSTTFLVGLCQAIDLRHLEENLKSTVKTTISQVAKRVLTSGINGELHPSRFCEKDLIKVVDREHVFSYVDDPCSATYPLMQRLRQILVEHAMNNGEKEKDADTSIFRKISAFEDELKVVLPKEVESARVAYENGTSAIKNRIEECRSYPLYRFVREETGTSLLTGENVRSPGEEFDKVFNAICEGRLVDPLLECLEDWNGAPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase 1.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_DESHY
Sequence: MISSNEFKTGLTIEVDNDVYTIIEFQHVKPGKGAAFVRTKLKNVKTGGITERKFNAGEKVPKAHVERREMQYLYKDGDHFVAMDNETYEQTSLTEAQIGDGVKYLKENMNLGILFFNGTVIGVDLPNTVILEVAHTEPGVRGDTATGGSKPATLETGAVVQVPFFVNEGEKLIIDTRTGNYVQRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.