PharMolix/UniProtQA huggingface dataset:
Protein: SE1L1_RAT
Sequence: MQVRVRLLLLLCAVLLGSAAASSDEETNQDESLDSKGALPTDGSVKDHTTGKVVLLARDLLILKDSEVESLLQDEEESSKSQEEVSVTEDISFLDSPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEAIYQSGMKILNGSTRKNQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDDDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIREANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDIPVPRPPGPRPAPPQQEGPPEQQPPQ
What is the function of this protein?
Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Enhances SYVN1 stability.  Plays a role in LPL maturation and secretion.  Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells (By similarity).  May play a role in Notch signaling (PubMed:11401526).
What are the official names of this protein?
Protein sel-1 homolog 1, Suppressor of lin-12-like protein 1, Sel-1L.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: UVRB_STRAW
Sequence: MRPVSKIERTVAPFEVVSPYQPSGDQPAAIAELDRRIRAGEKDVVLLGATGTGKSATTAWMIEKLQRPTLVMAPNKTLAAQLANEFRELLPNNAVEYFVSYYDYYQPEAYVPQSDTYIEKDSSINEEVERLRHSATNSLLTRRDVVVVASVSCIYGLGTPQEYVDRMVPLRVGDEVDRDDLLRRFVDIQYTRNDLAFTRGTFRVRGDTIEIFPVYEELAVRIEMFGDEIEALSTLHPLTGEIISDDQHLYVFPASHYVAGPERLERAANDIEKELGERLTELEKQGKLLEAQRLRMRTTYDLEMLRQIGSCSGVENYSMHFDGREPGSPPNTLLDYFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVDHGFRLPSALDNRPLKWEEFQERIGQAVYLSATPGKYELSRGDGFVEQIIRPTGLIDPEVVVKPTEGQIDDLVHEIRKRTEKDERVLVTTLTKKMAEDLTDYFLELGIQVRYLHSDVDTLRRVELLRELRAGEYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMYADKITPAMEKAIDETNRRREKQVAYNKEKGIDPQPLRKKINDIVAQIAREDIDTEQLLGSGYRQAKDGKGAKAPVPSLGGKAAAKGAKSAKGKAKETVPTDRPAAKLAEEIEELTNRMRAAAADLQFEIAARLRDEVSEMKKELRQMKEAGLA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIJO_ECOLI
Sequence: MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLEIVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWDGKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQIQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYLNHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLTEKPTTPE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YijO.
Protein: PSRP_METFK
Sequence: MQKRSVFFISDGTGITAESVGHLLAHFPTVSFKHIRLPFTDSEQKVQEALLKIAETEKADGARPIVVMTLVNTDLRDMLKQSNAVHLDVFGSFVDPLAEELQEQPSRTSGIAHSVLGNSYYERIDAINFTLNHDDGMTDFGLSEAQVILVGVSRCGKTPTSLYLAMQFGIKAANYPLIPEDLERGSLPEALKKYPEKLYGLSINPERLHSVRSERRPDSHYASLDNCRREIRLAEDLMHREGISWIDSTSRSIEELSTIILQKIRVNSNH
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: NDK_SCHPO
Sequence: MSTEQTFIAVKPDAVQRGLIGYIISKFELKGYKLRALKFLVPSRDLVEEHYAEHKGKPFYEKLVGFMASGPVCAMIWEGKQAVKTGRLMLGASNPLDSAPGTIRGDYGIDLGRNVCHGSDSIESANREIKLWFQPSEIQVYDRTIEPWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: MDR1_TRIIM
Sequence: MASQPPQPPSGQPDTQYEEYQSEVITETTNRPTPAADVYEITPTNDVMDDRYEHEHDDYESGAMYETVRTWSPQSRPELVRIASVFSRIDSHPDVAPTTEDGGQLNRRDTLAGVKIGDPVLDPTKPEFDFYKWARMFTHVMEKEGIKRNRTGVMFRNLTVLGSGSAVQYQDTFLSPFAAPFRPGELCGKGRNPEKVILHDFNGAIREGELLMVLGRPGSGCSTFLKAICGELHGLQKKKESIIHYNGVSQHTFKKELRGEAVYSAEDEHHFPHLTVGQTLEFAAAARTPSKRVLGLSRKDFSTHLARVMMSVFGLSHTYNTKVGDDYVRGVSGGERKRVSIAEIALSGAPICCWDNSTRGLDSATALEFTKALKIGSQVGGITQCLAIYQASQAIYDIFDKVIVLYEGRQIFFGPTRIAKQYFEEMGWYCPPRQTTADFLTSVTNPKERIAKEGYENRVPRTAVEFERYWKQSQNNKLLLANMDRFEAEYPPEEGHLEKLRETHGQAQAKHTASKSPYRISVPMQVKLCTVRAYQRLWGDKSSTIATNISQIMMALIIGSLFFDTPQTTDGFFAKGSVIFFAILLNGLMSITEINGLCKATEPIVPNAQRPIVVKHVNFAFYHAYSEALAGIVADIPIKFLLALVFNIIIYFLGGLERSAAKFFIFFLFTFITILTMSAIFRTLAAATKTIPQALALAGVMILALVIYTGFTLQPSYMHPWFKWILYINPIAYAYEALLVNEVHGNRYRCATPIPPYGSGKNFACAVAGAVPGEMSVSGDAWVESSYDYSYAHIWRNLGILLGFLAFFYFVYLMVSELNLSSASSAEFLVFRRGHLPKNFQGSKDEEAAAGGVMHPNDPARLPPTNTNGAAGETAPGGSTVAVIPPQKDIFTWRNVTYDITIKGEPRRLLDNISGWVRPGTLTALMGVSGAGKTTLLDALAQRTTMGVITGDMLVNGRPLDSSFQRKTGYVQQQDLHLETTTVREALRFSADLRQPKSVSRKEKYEYVEDVIKMLSMEDFSEAVVGNPGEGLNVEQRKLLTIGVELAAKPQLLLFLDEPTSGLDSQSSWSIVTFLRKLADNGQAVLSTIHQPSGILFEQFDRLLFLAKGGRTVYFGDIGKNSETLLNYFETHGAEPCGPSENPAEYMLNIVGAGPSGKSNIDWPVVWKESEESRHVQQELDRIQSETSKRNEGHGQSAEKEPGEFAMPFTSQLYCVTTRVFQQYWRTPSYIWGKLLLGLASALFIGFSFFLQNSSMAGLQNSLFSIFMLTTIFSSLVQQIMPRFVTQRDLFEVRERPSRAYSWKVFLLANIIVEIPYQILLGIIAWASLFYPTFGAHLSSERQGILLLYCVQFFIFASTFAQMIIAGLPDAETAGGIATTMFGLMVTFNGVLQKPNALPGFWRFMWRVSPITYTVGGLAATSLHSREVKCAQNELAIFDPPSGATCAQYLQKLVEAGAPGKLYNPMSTSQCQYCPLSSGDQFLGGSEIHWSDRWRNFGIGWAYIVFNIFATVALYYLIRVRKSSGRPNRIISVITYHLSQFGTYCRAFITGRKEKCPRKREQIGKIY
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds, including ethidium bromide, ketoconazole, cycloheximide, fluconazole, griseofulvin, imazalil and itraconazole.
What are the official names of this protein?
ABC multidrug transporter MDR1, Multidrug resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXH_FRACC
Sequence: MGGPDPDVPDLDVPDPALLRQGYRAGRLEPEHLAPTWVEQFAAWFIDAATPGVGVPEANAAVFATASAAGRPSARTVLLKGFDQRGFVIYTNYASRKGREATENPFGSLVFPWYALERQVVVIGSIERVSRAETERYFQSRPHGSQLGAWASHQSTIIESRTVLDDRAAELAARWPEGTRVPTPEFWGGLRIVPDTVEFWQGRADRLHDRLRYRRVSVPADGGGTDSLAVADPDATGVRVGDAGGGDAGGGVPTAAEDLWVVERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL17_THET2
Sequence: MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ESTA_PSEAE
Sequence: MIRMALKPLVAACLLASLSTAPQAAPSPYSTLVVFGDSLSDAGQFPDPAGPAGSTSRFTNRVGPTYQNGSGEIFGPTAPMLLGNQLGIAPGDLAASTSPVNAQQGIADGNNWAVGGYRTDQIYDSITAANGSLIERDNTLLRSRDGYLVDRARQGLGADPNALYYITGGGNDFLQGRILNDVQAQQAAGRLVDSVQALQQAGARYIVVWLLPDLGLTPATFGGPLQPFASQLSGTFNAELTAQLSQAGANVIPLNIPLLLKEGMANPASFGLAADQNLIGTCFSGNGCTMNPTYGINGSTPDPSKLLFNDSVHPTITGQRLIADYTYSLLSAPWELTLLPEMAHGTLRAYQDELRSQWQADWENWQNVGQWRGFVGGGGQRLDFDSQDSAASGDGNGYNLTLGGSYRIDEAWRAGVAAGFYRQKLEAGAKDSDYRMNSYMASAFVQYQENRWWADAALTGGYLDYDDLKRKFALGGGERSEKGDTNGHLWAFSARLGYDIAQQADSPWHLSPFVSADYARVEVDGYSEKGASATALDYDDQKRSSKRLGAGLQGKYAFGSDTQLFAEYAHEREYEDDTQDLTMSLNSLPGNRFTLEGYTPQDHLNRVSLGFSQKLAPELSLRGGYNWRKGEDDTQQSVSLALSLDF
What is the function of this protein?
Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes is unclear.  In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents.  Also shows relatively high activity towards beta-naphthyl butyrate, whereas its activities towards triacylglycerols and acyls-CoA are negligible.
What are the official names of this protein?
Esterase EstA, Autotransporter esterase EstA.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RSMG_DEIGD
Sequence: MTPEGRALLLAGAAELGLELSAEHLDRFARLLVRLTEGSAQLNLTALHQERDIVLKHFVDSLTCLRGGWLDGAARVLDLGTGAGFPALPLAIVRPDLQLVALDATRKKVDFVERTARSLELNHVQPLTGRAETLGRDPAQRESYDRVVTRAVAALPILAELTLPFLRMGGFLLAQKGPIGPEELEAGTRAAQEVGGEIRAIDAFVLPVAGDARTLVVVEKTAPTPERYPRREGVPNRKPLFWRAT
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_TOBAC
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFVEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAQEGNEIIREACKWSPELAAACEVWKEIVFNFAAVDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process (PubMed:3681999, PubMed:2928307).  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACDA2_PYRFU
Sequence: MLDYFFNPRGIAVIGASNDPKKLGYEVFKNLKEYQGGKVYPVNVREEEVQGVKAYKSVKEIPGEVDLAIIVVPKKFVKQTLIECGEKGVKGVVIITAGFGETGEEGKREEKELVEIAHKYGMRIIGPNCVGIMNTHANLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFADLMEYLADTQEDKAIALYIEGIKDGRRFIEVAKKVTKKKPVIALKAGKSESGSRAAASHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPKGNRVAIMTNAGGPGVLTADEIDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAKLLLQDPNVDILIAICVVPTFAGMTPTEHAEGIIRAVKEVNNGKPVLALFMAGYVSEKAKELLEKNGIPTYERPEDVAAAAYALVQQAKNVGGGVNG
What is the function of this protein?
Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate.  Can use other substrates such as phenylacetyl-CoA, indoleacetyl-CoA and isobutyryl-CoA, but not succinyl-CoA.  Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids.  Participates in the conversion of acetyl-CoA to acetate and in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters.
What are the official names of this protein?
Acetate--CoA ligase [ADP-forming] II subunit alpha, ADP-forming acetyl coenzyme A synthetase II subunit alpha, ACS II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the acetate CoA ligase alpha subunit family.
Protein: COL19_CAEEL
Sequence: MGKLIVVGSCGVLVCVLASLYTIGNLLNEIEELQVEFQDGMVEFRAITQDTWARMVSKHINPTGHTNAPPTFETLFGARTARQAGFEQCNCGPKSEGCPAGPPGPPGEGGQKGNPGHDGDDGKPGAPGVIVAITHDIPGGCIKCPPGRPGPKGPSGLPGSAGPAGGNGRRGPPGPVGGPGEQGPQGDAGRPGAAGRPGPAGPRGEPGTEYKPGQPGRPGPQGPRGETGPAGNPGAPGNDGEAGKNGNAGRPGPPGHPGKNGVPGQKGEDAAPGPDAGYCPCPSRAAYKA
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen 19.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: SYH_ORITB
Sequence: MSIKLQPVKGSKDLLPEEFGKHDYIISVSRNLSKLYGFQPISTPIIEYTEIFNRTLGKDSDVLSKEMYVFLDKGNRSVSLRPEFTASIMRAVIYNNLQNKKLPLKYFSSGPAFRYDNPQAGRQRQFHQINLECIGDGSPFSDAEIVLLAYDILKKLNLVDKVNLEINSLGCMESRAKYQQALVEYFSKYRTELSQDSQSRLIENPLRILDSKNLHDKKISASAPSIHDYYTIEARGYFDKVLEYLEFCGIKYTINANLVRGLDYYCHTVFEYVSTQIGAQSTVLGGGRYDGLFEQMGGKLASGKKMLPAIGFAAGIERLALLTNYTPVDVRPIVIIPVDEEYHQHGIILLQKLRNNNITTVIDLQDSISKRLNRANHIKASKVIFIGAIEMREQSYRIKDLDTSNECVIIHNELLSYLQNNCS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SYNY3
Sequence: MGAKSMEGMNLKQTAIADFHHVSVLPTALVEGLEPKPGGYYLDATVGAGGHSERLLKLGIPLALTMIDRDVQAIAAAMERLQPLVADRKDISINTWQGNFADFPGQLEQFDGIIADLGVSSPQLDQGDRGFSFRHTAPLDMRMDQSQDLTAAEIINHWSEKDLARIFYEYGEERLSRRIARQIVEQRPFQTTTDLAEAITKWVPGKYRHGRIHPATRTFQGLRIAVNDELGSLEKFIAQAPHWLKSGGKFGIISFHSLEDRIVKHRFRETENLRVLTKKPIIAGEEEQRQNPRARSAKLRWAEKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PON2_HUMAN
Sequence: MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
What is the function of this protein?
Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters.  Has antioxidant activity.  Is not associated with high density lipoprotein.  Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
What are the official names of this protein?
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the paraoxonase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: SYD_YERPA
Sequence: MRTEYCGQLNLSHVGQSVTLCGWVNRRRDLGGLIFIDMRDREGIVQVFFDPDHKAAFEQASELRNEFCIQITGTVRARPDSQINKDMSTGEVEIFANTLNIINRSEPLPLDSNQINSEEQRLKYRYLDLRRPEMADRLKSRAKITSFVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMSADQVREVMEKLVRELWQETKGVDLGDFPVMTFAEAMRRYGSDKPDLRNPLELVDVASLVKDVEFKVFSGPANDAKGRVAALRVPGGAQLSRKQIDEYGQFVGIYGAKGLAWLKVNDRAAGLEGVQSPIAKFLSAEVLDAILVATQAESGDILFFGADSYKIVTDAMGALRLKVGRDLELTRLGTWAPLWVVDFPMFEDDSEGGLTAMHHPFTAPKDMSPEQLAAAPTTAIANAYDMVINGYEVGGGSVRIHRTEMQQTVFGILGITEDEQREKFGFLLDALKFGTPPHAGLAFGLDRLVMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANPASLQELSISVVAKKGTTDAGAEENQ
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LYSSC
Sequence: MAYEKLAVQDKAVLEGILAEKKRQQANIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEYANVQPHSGAQANMAVYHTILEPGDTVLGMNLSHGGHLTHGSPVNFSGILYNFVEYGVTKDTQVIDYEDVRQKALEHKPKLIVAGASAYPREIDFSKFREIADEVGAYFMVDMAHIAGLVAVGEHQSPVPYADFVTSTTHKTLRGPRGGLILASKEWEQKLNKSVFPGIQGGPLMHVIAAKAVAFGEVLQPEFKDYAKQIKLNAKALAEVLIAEGVEIVSGGTDNHLLLLNVKSLGLTGKVAEHALDEVGITTNKNTIPYDTESPFVTSGIRIGTPAVTSRGFKEEDMKEVGAIIAAVLKNPEDEAVKADAKDRVKALTDKHPLYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNS3_AHSV1
Sequence: MNLASISQSYMSHNENERSIVPYIPPPYHPTAPALAVSASQMETMSLGILNQAMSSSAGASGALKDEKAAYGAVAEALRDPEPIRKIKRQVGIQTLKTLKVELSGMRRKKLILKIIMFICANVTMATSLVGGMSIVDEDIAKHLAFDGKGDWVSKTVHGLNLLCTTMLLAANKISEKVREEIARTKRDIAKRQSYVSAATMSWDGDSVTQLRDVKYGD
What is the function of this protein?
May play a role in the release of virions from infected cells.
What are the official names of this protein?
Non-structural protein NS3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus NS3 family.
Protein: SSB_RHILO
Sequence: MAGSVNKVILVGNLGADPEIRRLNSGEPVVNIRIATSESWRDKNSGERKEKTEWHNVVIFNEGIAKVAEQYLKKGMKVYVEGQLQTRKWQDQTGADKYTTEVVLQRFRGELQMLDGRQGEGGQVGGYSGGGSSRGSDFGQSGPNESFNRGGGAPRGGGGGGSSRELDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: PDXT_CLOK5
Sequence: MRIGVLSFQGGVIEHIHHIESLKAIPVEIKNKYELNNIDGIILPGGESTTMGKLLMDTDMLEPLREKILKGLPTWGTCAGMILLANSIENSNKSYLKVIDIKVRRNAYGSQIDSFYYETLIPDISSSKIPLVFIRAPFITYLGSNVKSLCSIKGNVVAARYKNILVTSFHPELTDDLSFHKYFLSTCR
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RL4_CYAP4
Sequence: MVACVIKDWQGSEVGETALELRVAKAENAAHIVHRALRRQMANARQGTASTKTRAEVRGGGRKPWRQKGTGRARAGSNRSPLWRGGGVIFGPKPRDYSIKMNYKERRLALRTALISRSDSLIVVEDFSDKLPRPKTKELAAAIARWGVQPNDKVLLIVADKQDTIYLSARNIATVKLIQATSLNVFDLLNADWIVATVEALGKIQEVYGG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MT2A_RABIT
Sequence: MDPNCSCAAAGDSCTCANSCTCKACKCTSCKKSCCSCCPPGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2A, MT-2A, Metallothionein-IIA, MT-IIA.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RS16_SHIBS
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NADK_NOCFA
Sequence: MSGSGDREILLIAHPGRAEIVETAHRAAKIFTEAGIGLRVLADEAPSTRFDSRAEPAPVTGPAGDAVRVVEHSAAAAVGCEMVLALGGDGTFLRAAELARPASVPVLGINLGRIGFLTEAEAEHLDEALGQVVRGDYRVEDRMTIDVTVRVEDEVVESGWALNEASIENASRMGVLEVVLEVDGRPVSAFGCDGILIATPTGSTAYAFSAGGPVVWPELEALLVIPSNAHALFARPLVTSPESRIAVESVATGHDAIVFLDGRRTLALPRGGRVEAVRGSEPVRWVRLDSAPFADRMVRKFQLPVTGWRGRRRTESTRADRDQD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHAC_SCHPO
Sequence: MKTLSPEGSLWVFGYGSLIWHPPPHYDYSIPCFIKGYVRRFWMRSEDHRGTVNSPGLVLTLIPYEEWKQFSDWSFTPFDEGCWGMAFRIPAKYATQVREYLDDREVNGYTAHSVPVYAHTGDEIPVLENCLVYVGTSKSPQFQPSDDLTQMAKIISTRRGKSGDNFVYLFELAKCLRHLSPESKDIHVFELEAEVRKQMQKTR
What is the function of this protein?
Gamma-glutamylcyclotransferase acting specifically on glutathione, but not on other gamma-glutamyl peptides.  Allows utilization of gluthathione through subsequent cleavage of the Cys-Gly dipeptide by Cys-Gly metallodipeptidase dug1.
What are the official names of this protein?
Glutathione-specific gamma-glutamylcyclotransferase, Gamma-GCG.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RK14_MORIN
Sequence: MIQPQTHLNVADNSGARKLMCIRIIGASNRRYAKIGDVVVAVIKEAIPNTPLERSEVIRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQERNPKGTRIFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.