PharMolix/UniProtQA huggingface dataset:
Protein: LFTR_NEIMB
Sequence: MRIPLLAPDNYAFPDPAYALARCDGLVGVSGDLDAGRLLEAYRNGVFPWFSRDGWFFWYAVGPRAVVFPDRLHIPRSLAKTLRNGSYRVAVNGCFAEVVAHCAAAARPNQDGTWIAPEFQTAYLKLHEMGYAHSFECHYPDESGETRLAGGFYGVQIGRVFYGESMFALQPDASKIAFACAVPFLADLGVELIDCQQDTEHMRRFGSELLPFADFAERLRMLNAVPLKEEIGRREVACKGL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2B_DROME
Sequence: MASTSRLDNNKVCCYAHPESPLIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNEKSGVDPSRVGGPENPLLSGGDLSTIIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLFKQVHDGKNLKGRSNDAKASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKLTLKALETSVDLITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDIVPGRSPISVAAAAIYMASQASEHKRSQKEIGDIAGVADVTIRQSYKLMYPHAAKLFPEDFKFTTPIDQLPQM
What is the function of this protein?
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ESR1_ASPUN
Sequence: GHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRILKHKRQREEHDNRNAGAIVERRSPNLWPSPLMITHNKKNSPALSLTADQIVSALLEAEPPVVYSEYDPSRPFSEASMMTLLTNLADRELVHMINWAKRVPGFVDLSLHDQVHLLECAWLEILMIGLVWRSVEHPGKLLFAPNLLLDRNQGKCVEGFVEIFDMLLATSSRFRMMNVQGEEFVCLKSIILLNSGIYTFLSSTLKSLEEKDHIHRVLDKIIDTLLHLMAKSGLSLQQQHRRLAQLLLILSHFRHMSNKGM
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALKB3_HUMAN
Sequence: MEEKRRRARVQGAWAAPVKSQAIAQPATTAKSHLHQKPGQTWKNKEHHLSDREFVFKEPQQVVRRAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLCQDVPWKQRTGIREDITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW
What is the function of this protein?
Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (PubMed:12486230, PubMed:12594517, PubMed:16174769, PubMed:26863196, PubMed:26863410).  Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation (PubMed:12486230, PubMed:12594517, PubMed:16174769, PubMed:25944111).  Has a strong preference for single-stranded DNA (PubMed:12486230, PubMed:12594517, PubMed:16174769, PubMed:20714506).  Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3 (PubMed:22055184).  Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA (PubMed:25797601).  Also acts on RNA (PubMed:12594517, PubMed:16174769, PubMed:26863196, PubMed:26863410, PubMed:16858410).  Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons (PubMed:26863196, PubMed:26863410).  Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:22055184, PubMed:16858410).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, Alkylated DNA repair protein alkB homolog 3, hABH3, DEPC-1, Prostate cancer antigen 1.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage (PubMed:29144457). Predominantly localizes to the nucleus.
Protein: SWT6B_ORYSI
Sequence: MISPDAARNVVGIIGNVISFGLFLAPVPTFWRICKRKDVEEFKADPYLATLLNCMLWVFYGIPIVHPNSILVVTINGIGLVVEGTYLFIFFLYSPNKKRLRMLAVLGVELVFMLAVILGVLLGAHTHKKRSMIVGILCVFFGSIMYFSPLTIMGKVIKTKSVEYMPFFLSLVCFLNGVCWTAYALIRFDIYVTIPNSLGAIFGAIQLILYACYYRTTPKKTKAAKDVEMPSVISGPGAAATASGGSVVSVTVER
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET6b, OsSWEET6b.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GP157_RAT
Sequence: MPTPAPPTELLPWERAVVLLSCVLSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQDFAGTSWDCVLQGALSTFANTSSFFWTVAIALYLYLNIVRATRGPCTDHLVWAFHLISWGVPLAITVAAVCLKKIGYDASDVSVGWCWINLEAEDRVLWMLLTGKLWEMLAYILLPLLYLLVRKHINRAHQALSEYRPIWEGRQLQRGSPTSMADKKLILIPFIFICLRVWSTVRFVLTLCGSPVVQAPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCYPRPPTQNPPGASIPPKMGESQESRRTPEVPST
What is the function of this protein?
Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs).  The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
What are the official names of this protein?
G-protein coupled receptor 157.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid.
Protein: SECA_CALS4
Sequence: MLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGETLDDILPEAFAVVREAAWRTLKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVILHDMGPAERKKAYAADITYGTNNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKLADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKAHAIMKRDRDYVVKDGQVIIVDEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATITLQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHKPMIRIDHPDVIYKTEEAKFRAVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGRKGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARERYFELLEEAKKETEKEHEEVVKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYISLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIEQAQKKVEGINFDIRKHLLQYDDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLDHLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLRVVDTKWMDHIDEMDQLRQGIGLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRIQVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGRNDPCPCGSGKKYKKCCGANVK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: HTPG_LEGPH
Sequence: MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSEISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKLQSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANKUB_HUMAN
Sequence: MRIFIAFEGSFEPFDVSADETVEVVKLMIKDYFHIPLSEDKQGRRYLELMYAGAALKDSWSLADVGISFCSTLKCFVKEEDKPTLYVFNAVTQDTMPVMESISLLDKTVSDLRTLVTLRCGLPVSVYCLRTPRGLEMYDCNTLKDYQTDIGTTLRLDVWDGWKEFLMGCLLGQKLKVQRYLSKEGPVLKYQKRVALYIAAFCGYIELTEWALKQGARPHEAVGVHPYRAWCHEALHADVSKCPIHAAAEAGQLLILKAFVNYSVLCLECKNAAGQTPLTIVFKHKHKDCVLYLLSKMWSTVSFPKISVPMRIYIKIKQWILRAQSHSLHKSQFCGARVFGAKVGDTVMVDGFTKPKMTSKSWHKAGNSDSQSIVLKLPSLSKQTASSKPVNPLAISQPDTRKQALKFHPLVNASSFSELQKHQQQNQKKITATARKKEKLIKNTYLPQVPLPPVSRVGYSHPSFFYATPSADFLLKSSFSSFLEHSGKTPWENAIYCLAVAR
What are the official names of this protein?
Protein ANKUB1, Ankyrin repeat and ubiquitin domain-containing 1.
Protein: PPR10_MAIZE
Sequence: MEATGRGLFPNKPTLPAGPRKRGPLLPAAPPPPSPSSLPLDSLLLHLTAPAPAPAPAPRRSHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHWEWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNRVTWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSEAREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIEDAQFGR
What is the function of this protein?
Involved in chloroplast mRNA stability (PubMed:19424177, PubMed:21173259, PubMed:22156165).  Binds specifically to two intergenic RNA regions of similar sequence located in the chloroplast atpH 5'-UTR and psaJ 3'-UTR, and serves as a barrier to RNA decay (PubMed:19424177).  Binding to a specific site in the intergenic region of the chloroplast atpH is sufficient to block 5'-3' and 3'-5' exonucleases (PubMed:21173259).  Acts as protein barrier to block mRNA degradation by exonucleases, and defines processed mRNA termini in chloroplasts (PubMed:22156165).  Remodels the structure of the atpH ribosome-binding site in a manner that can account for its ability to enhance translation (PubMed:21173259).  Stabilizes a RNA 3'-end downstream from psaI (PubMed:30125002).  Binds atpH RNA as a monomer (PubMed:25609698).
What are the official names of this protein?
Pentatricopeptide repeat-containing protein 10, chloroplastic, ZmPPR10.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: OBG_TRIV2
Sequence: MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVVFVAVENLQTLLDFRYKHIFKADDGGRGGPNNCTGASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQQLLIAAGGKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLAEVGIIGLPNAGKSTLISSLSAARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRVLLHLIDATSDDVIRDYNTIEQELQAYGRGLSERMQIVALNKIDAVDRETVDLDALATQLNHLSHAPVFLISAVTRTGLEPMLQEVWGILDQVNALEEAEVFR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_WOLSU
Sequence: MNRLGELWVLTTFGESHGAGIGCVLDGVPAGLRVDEEFLNLELSRRRPGQSLYSTPRKESDRVEILSGVMEGFTTGTPLAMFIPNENQKSSDYESIRSIFRPGHADFTYHYKYGLRDHRGGGRSSARETAARVAGGAVAKMFLKELGISIFSGVFQVGEHTSDVRDFAHARKSVVNALDPLMEELFKEEIEKARGAHDSIGGAIEVRAKGMPIGLGEPLYHKLDGALGGALMGLNAVKAVEIGEGLSAARLKGSENNDPLRLEGFKSNHAGGILGGISNGSELVARVYFKPTPSIFLPQETLNEEGDEVICALKGRHDPCVAIRGGVVCEALVALVLADMALLRLGNRLQDVKEFYGKGR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TRPA_DICT6
Sequence: MANLLEKFKNRDKSLLFVPFFVSGFPDFDFLEKFLFKNKDKIDILELGVPFSDPVADGPILQEINYRAMVKGVNLNNTLDWLLDSGITKKIDVILLLYFNLIQNKLEEKLKRFKEVGIKGLVIPDLPLEEAEKLIPLFNEHNLDLILFISPTTREERIRKILDIAPSFLYCISVKGVTGERDRLPEEGVAFISRVKKETNKPLVWGFGLGSSYQINSLKGLVDGVIVGSAIGKRLLNNEDIQDYFDELYKATL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ATPF_VAULI
Sequence: MKNWISSFILVHQEKSISFNTNILETNLINIIILLIILFYFLKGLLKDNLSSRQENILSTIQNSENRINEANERLVDAKLQWSQAQITLEELKNQTLQNKLILFNAEFEIKNQVLSQHFNNLLMTLYYREQQAFNNIKKQVSELALKKVIAKLQAPLMEEDQSVIIINKIHRLGGNLE
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: WNT2_CARPS
Sequence: MNAPLGGIWLWLPLLLTWLSPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRNPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGSSRDNKGTFDWGGCSDNIDYGIKFARAFVDAKERQGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWKKYSGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWAAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SURE_ECOLU
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADKVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G4P_BPI22
Sequence: MKTFFAKFIVALFAFTYFSAFAEPVTLNNSPVRSFVQWYSSKTGKSVIVNPDVKGNITVFNADVNNANIDDFFKSVLNANGLVVVAGNPAVVSTPLTKLASQPSNEETYDDESDGVAYEAVPQSAAPAVPADLTVRNFNVTRVRSSDVLPLAKIFVDSNGGGNVVDYPGNNSLVVSGSAQVMPALSDFITSIDVAREQVLIQSLMFETSVSNGVDLSFALALASGGKVAGGFNTSALGTALSTAGGSFGIFNGNILALSLQAVQSDSNSKVISTPRILTQSGQSGYISVGQNVPFVTGKVTGEAASVNNPFQTIERRDVGVSLKVTPVVMGNGQLVLTIDTKADSLSNQAIASDIITNQRQIQTTVQIKDGQTLLLGGLISSNQFDSDRSVPFMSKIPLIGWLFRSHSDSKDDRTMFVLLTAHVIRAL
What is the function of this protein?
Acts in the assembly and extrusion of the bacteriophage by forming a channel across the host outer membrane.  This channel is just large enough to allow a newly synthesized phage particle to pass through.  Extrusion is a process of concomitant assembly and secretion and takes place at specific assembly sites where host inner and outer membranes are in close contacts (By similarity).
What are the official names of this protein?
Virion export protein, Gene 4 protein, G4P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G4P protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: UBP12_BOVIN
Sequence: MEILMTVSKLASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDSENNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD
What is the function of this protein?
Deubiquitinating enzyme.  Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.  Not involved in deubiquitination of monoubiquitinated FANCD2.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 12, Deubiquitinating enzyme 12, Ubiquitin thioesterase 12, Ubiquitin-specific-processing protease 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: G3P_ECOL6
Sequence: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_NUPAD
Sequence: MEKWWLNSMLSNEDLGRRCGLSASLGPIGNTSGSEEPITNDNEKNIHSWSGRGSYSYSNVDYLLGLDGVKDIWSLISGDTFWVRDSNGDSYSVYFDIENKIFEIDTDSYFLGELESLFSSYLNLNSGSKDYNRYYDQYVYDTRHSWKNHINSCIDSYIRSETNMDSCISNGSNNSSDNYIYSYICSDSERGSDRGSSNLKTSVSDFGRHSDLDRNLKYGHLWVQCENCYGLNYKKFFSSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDENMVSIDPIEFHSEEEPYRDRINSYQIETGLAEAVQTGIGKLNGIPIAIGVMDFKFMGGSMGSVVGEKITRLIEYATDRSLPVIMVCASGGARMQEGSLSLMQMAKISSALYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLKKTVPEGSQVAEYSFHKGLFDPIVPRNLLKGVPSELFQFHGFFPRP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CLPB_BACCR
Sequence: MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQGAESLIKKKPSVTGSGAEVGKLYVTSALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTIFALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLREHLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVIIMTSNIGSAHLLDGLEEDGSIKEESRDLVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHITVELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_POLSJ
Sequence: MSIKSDKWIRRMAESTGMIEPFEPGQIREADGKKIISYGTSSYGYDIRCAPEFKVFTNIHSTVVDPKNFDEKSFVDFHGDSCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEVCETSYKDRGGKYQGQQGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.