PharMolix/UniProtQA huggingface dataset:
Protein: RERE_RAT
Sequence: MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDNGATTEESARKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPAPALCDPPACSLPVASQPPQHLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGGLHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGNVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAQKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL
What is the function of this protein?
Plays a role as a transcriptional repressor during development.  May play a role in the control of cell survival (By similarity).  Interacts with FAT1 (By similarity).
What are the official names of this protein?
Arginine-glutamic acid dipeptide repeats protein, Atrophin-1-related protein.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Localized in nuclear bodies of variable size. Colocalized with PML and BAX in nuclear PODs (By similarity).
Protein: ISPF_BUCAI
Sequence: MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MFPA_MYCS2
Sequence: MRIGANGDETVWADEEFAGRDFRDEDLSRIRTERVVFTECDFSGVDLSESEHHGSAFRNCTFRRSTIWHSTFTNCSLLGSVFTECRIRPVTFVECDFTLAVLGGCDLRAVDLSDCRLREVSLVGADLRKAVLRRADLTGSRVQDARLEEADLRGTRVDPTFWTTAKVRGAKIDIEQALAYAAAHGLAVHGG
What is the function of this protein?
When present on multicopy plasmids confers increased resistance to fluoroquinolone antibiotics such as ciprofloxacin and sparfloxacin but not the quinolone nalidixic acid (PubMed:11709313).  Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (By similarity).
What are the official names of this protein?
Pentapeptide repeat protein MfpA, Mycobacterial fluoroquinone resistance pentapeptide, Orf3.
What is the protein family that this protein belongs to?
Belongs to the pentapeptide repeat protein family.
Protein: ILVI_BUCAI
Sequence: MEILSGAEMVVRSLIDQGIQHIFGYPGGAVLDIYDALKTVGGIEHILVRHEQAATHMADGYSRSTGKTGVVLVTSGPGATNAITGIATAYMDSIPMVVISGQVASSLIGYDAFQECDMIGISRPIVKHSFLVKKTEDIPIVFKKAFWLASSGRPGPIVIDLPKDILKKDNKYLYKWPDNINIRSYNPTTKGHIGQIKKALHTLLKAQRPVIYAGGGIISSNSSEELRIFAEKINCPVTTSLMGLGSFPGTHDQNISMLGMHGTYEANMTMHHADVIFAIGVRFDDRTTNNLNKYCPNAIVLHVDIDPTSISKTVSANIPIVGDAKHVLQKMIELLKKEKKISLLEDWWNTIKKWKKINSLQYNQLSNKIKPQTVIKTLFKLTKGTSYITSDVGQHQMFTALYYPFNKPRRWINSGGLGTMGFGLPAALGVKLALPKETVICITGDGSIQMNIQELSTARQYNLAVLILNLNNSSLGMVKQWQDMIYSGRHSHSYMDSLPDFVKLSESYGHFGIQITEPIELEEKLMLALSKLSDGHLVFVDVQIDNSEHVYPMQIQGGGMNEMRLRKKEVA
What are the official names of this protein?
Acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: ARIR_ECOLC
Sequence: MLEDTTIHNAITDKALASYFRSSGNLLEEESAVLGQAVTNLMLSGDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM
What is the function of this protein?
Regulates expression of genes involved in acid-resistance and biofilm formation.  May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition (By similarity).
What are the official names of this protein?
Regulatory protein AriR.
What is the protein family that this protein belongs to?
Belongs to the AriR family.
Protein: RS10_PARP8
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: COAE_SHISS
Sequence: MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_WOLTR
Sequence: MAERANDIRPGQVLEHNGGLFLVVSIMHTQPGKGGAYIQAEMKNIKTGAKLYERFRSDATIRRAILDEEEYIYLFTEGNIVNLMHPSNYEQITINLDLLEEKKIYLQDNMRIKVVTYQDKIIFAHVPDYVRLTVKETESFIKGQTITSSYKPAVLENGMRINVPQFIKEEDKIVVYTPDDSYYERVKE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_PSEA8
Sequence: MHEQYQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIGHAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIATQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGLPIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGLGQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQLPVVLPEDVVPDGSGSPLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGKDWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTCRLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHAHVSAGLPGALDVATLSDAQKQVRRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLLAPITPHICHVLWGQLGHAEAVIDARWPSVDESALVQDTLQLVVQVNGKLRGHIDVAASASREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLXN_DANRE
Sequence: MNRKLIQNLAETLCRQVKHFNKTETECLIRLFNSLLGEQAERKTTIGVDRAKFRNILHHTFGMTDDMMTDRVCRVIDKDNDGYLSVKEWVEALSVFLRGTLDEKMKYCFEVYDLNGDGYISREEMFQMLKDSLIRQPTEEDPDEGIKDIVEIALKKMDYDHDGRVSYADFEKTVMDENLLLEAFGNCLPDAKSVLAFEQQAFQKHEHCKE
What is the function of this protein?
Regulates ciliary motility and is required for cilia-driven determination of body laterality.
What are the official names of this protein?
Calaxin, EF-hand calcium-binding domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ARLY_PARXL
Sequence: MTSQLHKKGEAWSARFSEPMSELVKRYTSSVFFDKRLALVDIEGSLAHASMLAAQKIIAADDLTAIQRGMAQIKGEIERGEFEWQLDLEDVHLNIEARLTALIGDAGKRLHTGRSRNDQVATDIRLWLRGEIDRIGGLLTELRTALLDMAEKNAATIMPGFTHLQVAQPVTFGHHLLAYVEMFSRDAERMIDCRKRVNRLPLGAAALAGTSYPIDRYAVAKTLGFDGICANSLDAVSDRDFAIEFTAASALVMTHISRFSEELVLWMSPRVGFIDLADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLIALLTLMKGQPLAYNKDNQEDKEPLFDTVDTVADTLRIFAEMVAGISVKPQAMRDAALQGFSTATDLADYLVKRGLPFRDAHEAVALAVRVCADRGCDLADLTLEEMRKELSNVAHLIGEDVFSYLTLEGSVASRNHPGGTAPEQVLAAVKAAREALK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_CLOB1
Sequence: MARKALIEKWNKTPKHSTRAYTRCRICGRPHAVLKKYGICRICFRELAYKGEIPGCKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: MACB_BRADU
Sequence: MTEPILALSHICREFMTGDTKVAALADVTLDIDRGELVAIIGSSGSGKSTLLNILGCLDHATSGSYRVAGEDVAALDADALAALRREHFGFIFQRYHLLSELPALENVEIPAVYAGDTASERQARAERLLARLGMAERRGHRPNQLSGGQQQRVSIARALMNGAEVVLADEPTGALDRRSGEEVLKILVELHREGKTIIIVTHDPEVAKRANRVIELRDGLVVSDKRTDAAVATAAASLPADKPDTRSSRWSGLAFRFRETLRMALLSMAAHRLRSFLTMLGIIIGIAAVSSVVALGNASQNKVLSDISNLGTNTIEVFPGKDFGDARAGKIKTLVLDDARALDRQTFIAGVTPTVSTSTTVRYRDRESNVLVNGVDRSYFQVKGTKIAAGALFDAVAVRNIERQAVIDDNTRRTFFSDDQNAGIGRVIWVGKVPCRVVGVIAQQQGGFGSNQNLSVYLPYTTVQAQFTGDRSLRSVLLRVSDEVSTDLAQEAVTTLLTRRHSTKDFVILNTDDIRRTITSTTQTLAFLVAAIAVISLVVGGIGVMNIMLVSVSERIGEIGVRMAVGARREDILQQFLVEATLISSLGGIAGILIAVALGALLNLLLPGFQVSYSTFSIGAAFLTSTAIGIFFGYFPARRAASFDPVVALSRE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYDP_SALPK
Sequence: MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: DER_CLOB1
Sequence: MAKPIVAIVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADKEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDESAGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTDFGEFTLIDTAGLRRKSKVKEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRVVKVLQTAKECYDNYNKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRENFDFQGTGIKSEFRERKEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL20_CAMJJ
Sequence: MARVKTGVVRRRRHKKVLKLARGFYSGRRKHFRKAKEQLERSLVYAYRDRRRKKRDFRRLWIVRINAACRLNDLSYSRFINGLKKAGIELDRKILADLAMNDAAAFAKIAEAAKKAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: P2C23_ARATH
Sequence: MGNGIGKLSKCLTGGAGRNKKPELSILEPDPLDEGLGHSFCYVRPDPTRVSSSKVHSEEETTTFRTISGASVSANTATPLSTSLYDPYGHIDRAAAFESTTSFSSIPLQPIPRSSGPIVPGSGPLERGFLSGPIERGFMSGPLDGSSGPIDGKTGSDQFQRSFSHGLANLRVGSRKGSLVRVLRRAISKTITRGQNSIVAPIKPVKEPDWVFGSDKTRIHQIENNLTVNSLNFSSEGSLLDDDVSLESQNLQWAQGKAGEDRVHVVVSEEHGWLFVGIYDGFNGPDAPDYLLSHLYPAVHRELKGLLWDDPKTDAKSSDEADVENRDSSSEKKSKNWEESQRRWRCEWDRDLDRLLKDRSNGLDLDPDPNSSDVLKALSQALRKTEEAYLENADMMLDENPELALMGSCVLVMLMKGEDVYLMNVGDSRAVLGQKAESDYWIGKIKQDLERINEETMNDFDGCGDGEGASLVPTLSAFQLTVDHSTNVEEEVNRIRKEHPDDASAVSNERVKGSLKVTRAFGAGFLKQPKWNNALLEMFQIDYKGTSPYINCLPSLYHHRLGSKDQFLILSSDGLYQYFTNEEAVSEVELFITLQPEGDPAQHLVQELLFRAAKKAGMDFHELLEIPQGERRRYHDDVSIVVISLEGRMWKSCV
What is the function of this protein?
Involved in leaf development regulation.
What are the official names of this protein?
Probable protein phosphatase 2C 23, AtPP2C23, Protein POLTERGEIST-LIKE 4, Protein phosphatase 2C PLL4, PP2C PLL4.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: E312_ADE03
Sequence: MSNGGAAELARLRHLDHCRRFRCFARELTEFIYFELSEEHPQGPAHGVRITIEGGIDSRLHRIFSQRPVLIERDQGNTTISIYCICNHPGLHESLCCLVCAEFNKN
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Probable early E3 12.1 kDa glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3A-2 family.
Protein: Y1752_STAA8
Sequence: MDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVKQFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SAOUHSC_01752.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: EFG_ECOK1
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_BARHE
Sequence: MPVITRFAPSPTGFLHIGGARTALFNWLYAKHTGGKMLLRIEDTDRERSTEAAVKAIIDGLHWMGLSYDGDPISQFERAERHRQVAEQLVKDGKAYYCYASPEELAEIRENARAEGRPPRYDGRWRERDISKAPKDIKPVIRIKAPQDGETIVHDRVQGDVRFPNKDLDDFIILRSDGSPTYMHAVVVDDHDMGVTHIIRGDDHLTNAARQTIIFNAMGWDIPVMAHIPLIHGENGAKLSKRHGALGVAAYRKMGYLPAALRNYLVRLGWSHGDDELMSIEDMISWFDIDDINKGAARFDLKKLDAINGHYIRMSNNQDLFDAALHILKEIEGGLQIMERLDEQRRAQFLKAIPNLKERSKTLCELIDNASFIFTKRPLQLDEKAQTLLDKNGLAILKVIYLALKACPSWDVKSLDETLRSYAQTQDLKFGSIAQPLRAALTGRLTSPGVFDVLVLLGRDESLNRINDQLVTTACSLHTNQCI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBE_NOTEU
Sequence: MVHFTAEEKTAITSVWGKVNVEETGGEALGRLLVVYPWTQRFFDSFGNLSSASAILGNPKVKAHGKKVLTSLGEAVKNLDNLKATFSKLSELHCDKLHVDPENFRLLGNVLVVVLAVHFGKEFTPEVHAAWQKLVAGVASALAHKYH
What is the function of this protein?
Hemoglobin epsilon chain is an embryonic-type beta-type chain found in prenatal and neonatal marsupials.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS2_PSECP
Sequence: MPVVTMRQLLDSGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLQQSLSYIDRAYEFVKATVAHGGTVLFVGTKKQAQEAIAEQATRVGQPYVNQRWLGGMLTNFQTVAKRIQRMKELEEIDFDDVAGSAYTKKELLLLKRELTKLESNLGGIRNLTKAPSVLWIVDTKKEHLAVDEAKKLNIPVVAILDTNCDPDEVDFPIPGNDDAIRSVNLLTRVVADAVAEGLIARNNRGSGTTEAPEEPLAEWERELLEGSKAEEAAAAAPAENAEAPAAPAAEAPAAAEAPAEDAK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LONM_DEBHA
Sequence: MLRPRTYVRKLAWRCPRKSQLGLRLATSVSSHKSLPLPMNFDISHSQSAFRAYQDIIHRNKSVGDDEPSQRSENENNPSESDKDSNQDPETPKKDKESENDKEPEKEKDIENDNKVSSESNENVTLASSNTGGAAPPNGNNNGDDPDDSNPSLPVDPVTGLYPPLLAIPMKDRPPLPGRPFAINVTDPEVIRSIYTIIDKREPYFVLFHVKDSNEPDTDVINKKDSVYDIGVHCQIIRHTTPRPGVFNVLGYPLERCKLEELTTPSSEKEAKSEEPSKEDAESFPTSYLKGLNVSYATVKPVEDEPYDKSSAEIRSLVESLKTLLSKMGGKNPLEKLQIKEGTDLISDPSKFADFVGSTIHGDPKKIQEILETLNIETRLSRALELLKVELKASLIKESTIHNLSTKADEYQTRLFIKEFIKELQKRAGISESEDKKTSKFDERLKHLKLTEEAMEAYNAEKAKMENQNEHSSELGVSERYLDWLTSIPWGVYSKDHFNIKQAREVLERDHYGLKDVKDRILEFISLGKVSGKVDGKILCLAGPPGTGKTSIAKSIAESLNRKYVRIAMGGIQDVHEVKGHRRTYVGSIPGRIISALKQAKTSNPLMLIDEIDKLDLSRGGGAASAFLEILDPEQNNSFVDNYIDVKVDLSKVLFVCTANYLGNIPAPLRDRMEIIDVSGYTNNEKIEIAKRHLIPEASKKAGLETNHVSITNETISRLIEKYCRESGLRNVKKLITRIFSKASLKIVEEIEAKEALDSSKEKEGVTASSEEANVNSESTKSNTSQAEPVAESSTDISTKSKVASEKIETKEKKETNKENGQSEEDQQPEPKFVIPEDIKLEITPANLKDYVGPEIYTRDRVYEFPPPGVATGLSYSTSGNGDALYIESILTHSIGSGSGVPGMHVTGSLKDVMKESASIAYSFTKSFMAKNYPDNRFFEAADIHVHCPDGAIPKDGPSAGISFTSSLVSLAINESLPPTVAMTGEITVTGRVLPVGGLREKILGAKRYGCDTIIFPKDIENELEEIPDEVKDGVTFIPVEWYQEVFDKIFPNATAQKCNEVWKEEFAKLDSKKKNKKK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ACPS_CAMFF
Sequence: MIGIDIVKIDRVTSAKSKFKSKFIYKFLLSSEVALVKNDASLAGIWAAKEAASKALGCGIGAELSFLDIEIYKDKKGAPKLKFNENIVKKFNIKNTSLSITHDGGFAIAAVIVEN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM8_MOUSE
Sequence: MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPTALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQERLEEREQDIEDQLYKLESDKRLVEEKVSQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQRLFDKTEDVGFMKNTKSVKILMDRTQTCTGSSLSPPKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVNSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASSEGQSGQPLGPCSSTQHLVALPGGTQPVHSSPVFPPSQYPNGSTTQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPGLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell survival, differentiation, apoptosis, and in particular, the innate immune response (PubMed:28747347, PubMed:31360105).  Participates in the activation of interferon-gamma signaling by promoting proteasomal degradation of the repressor SOCS1 (PubMed:12163497).  Plays a positive role in the TNFalpha and IL-1beta signaling pathways.  Mechanistically, induces the 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 component leading to the activation of NF-kappa-B (By similarity).  Modulates also STAT3 activity through negative regulation of PIAS3, either by degradation of PIAS3 through the ubiquitin-proteasome pathway or exclusion of PIAS3 from the nucleus (By similarity).  Negatively regulates TLR3/4-mediated innate immune response by catalyzing 'Lys-6'- and 'Lys-33'-linked polyubiquitination of TICAM1 and thereby disrupting the TICAM1-TBK1 interaction (PubMed:28747347).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM8, Glioblastoma-expressed RING finger protein, RING finger protein 27, RING-type E3 ubiquitin transferase TRIM8, Tripartite motif-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: FABD_MYCS2
Sequence: MLTPWLELPGAADRLAAWSQISGLDLTTLGTTATAEEITDTAVTQPLVVAATLLAHEELTKRGHSAAETIVAGHSVGEIAAYAIAGVISADDAVKLAATRGAEMAKACAVEPTGMAAVLGGDEAEVLARLEALDLVPANRNAAGQIVAAGAVAALDKLAEDPPAKARVRKLATAGAFHTHYMASALDGYAAAAQSVTTSEPTATLLSNADGQPVASAADAMEKLVAQLTKPVRWDLCTATLRDRFQNAESAGIVEFPPAGTLVGIAKRELKGTPTRAIKSPEDLDGLDQL
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.