PharMolix/UniProtQA huggingface dataset:
Protein: HUTH_BURCM
Sequence: MITLTPGHLTLPQLRKIARESVQLTLDPASFAKIDAGAKAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARSSVRLLMALKLSSLGRGHSGIRREVMDALITLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGVGEVFIRGERASALDGLRVAGLAPLTLQAKEGLALLNGTQASTALALDNMFSIEDLYRTALVAGALSVDAAAGSVKPFDARIHELRGHRGQIDAAAAYRDLLDGSPINQSHRDCDKVQDPYSLRCQPQVMGACLDQMRHAADVLLIEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIADNTKYILAIELLAAAQGVDLRAPYHTSPKLAPVMETIRGHVAHYELDHYFAPDIAVIAKLVSERAFAKVAPFSFASEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S23A2_HUMAN
Sequence: MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG
What is the function of this protein?
Sodium/ascorbate cotransporter (PubMed:10471399, PubMed:10556521).  Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (PubMed:10471399).
What are the official names of this protein?
Solute carrier family 23 member 2, Na(+)/L-ascorbic acid transporter 2, Nucleobase transporter-like 1 protein, Sodium-dependent vitamin C transporter 2, hSVCT2, Yolk sac permease-like molecule 2.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_MYCLB
Sequence: MSTAEKVQPRLKQRYRSEIREALNKQFSYGNVMQIPTVVKVVVNMGVGDAARDAKLINGAVSDLALITGQKPEVRKARKSIAQFKLREGMPIGVRVTLRDDRMWEFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQSVFHEIDVDKIDRVRGMDINVVTSATTDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RSMA_ENT38
Sequence: MNTRVHQGHLARKRFGQNFLNDQFVIESIVSAINPQKGQAMVEIGPGLAALTEPVGERLDEMTVIELDRDLAARLKTHPFLGPKLTIYQQDAMTMNFAELSEKLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQIIPVLEVPPTAFTPAPKVESAVVRLVPHAVMPHPVKELRVLSRITTEAFNQRRKTIRNSLGNTFTVDVLTELGIDPAMRAENISVEQYCKLANYISDNAPPKES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_METI4
Sequence: MMSKDKPQIPSGEKMLDIPEGLWTKCPGCNRFLYTKELELNQSVCHYCQHHFPLKAPERIACITDPGSFIECEKHLHSVDILGFNGEKSYQERLDYYRNKTALDEAVVCGSCTIGSIPVFLCVMDFGFLGGSMGSVVGEKITRMIEKSLSAKTPLLIISASGGARMYEGMFSLMQMAKTAAALQRLSQAHVPYISLLTNPTMAGVIASFASLGDVILAEPKAMIGFAGSRVIKETTQQELPPGFQTAEFLLEKGLIDKIVHRKELRSTLKQLLYFLT
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_MYCBO
Sequence: MLSPEALTTAVDAAQQAIALADTLDVLARVKTEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELAEGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQIRTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWGGCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 36016_ASFB7
Sequence: MLSLQTIAKMAVATNTYSKYHYPILKVFGLWWKNSTLNGPIKICNHCNNIMVGEYPMCYNHGMSLDIALIRAVKERNISLVQLFTEWGGNIDYGALCANTPSMQRLCKSLGAKPPKGRMYMDALIHLSDTLNDNDLIRGYEIFDDNSVLDCVNLIRLKIMLTLKARIPLMEQLDQIALKQLLQRYWYAMAVQHNLTTAIHYFDNHIPNIKPFSLRCALYFNDPFKIHDACRTVNMDPNEMMNIACQQDLNFQSIYYSYILGADINQAMLMSLKYGNLSNMWFCIDLGADAFKEAGALAGKKKKSVTAHIRS
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-16R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: PMGT2_TETNG
Sequence: MGVGTLLNGLLVSVVAALLWKYSKLSEHAALLEEELHMTRRSQELSQAHIDYHVALQALQEHGTRMVCTGKMHTDRICRFDYLCYCSEAEEFVFFHSNSSVMLPNLGSRRFQPALLDLSSVEDHNTQYFNFLELPAATLRFLPKPVFVPDVALILNRFNPDNLMHVFHDDLLPAFYTMKQFLDLDEDARLVFMEGWDEGPHFHLYRLLSDKQPLLKEQLRNFGKLMCFTKSYIGLSKMTTWYQYGFVQPQGPKANILVSGNEIRHFAKVLMEKMNVTRAEGGQEDEYIVVFSRSSTRLILNQAELVMALAQEFQMRVVTVSLEEQSFASIVQVIGAASMLVSMHGAQLITALFLPPGAVVVELFPFAVNPDQYTPYRTLAALPGMDLHYISWRNTEEENTITHPDRPWEQGGIAHLEKEEQERIVASKDVPRHLCCRNPEWLFRIYQDTFVDIPSFLEALQAGLKAKPVWKKSKLSGGLHPGRVRDARCQTSVQTSSEAKLTVSWQMPWNLKYLKVREVKYEVWIQEQGENTYMPYILPQQNYTFSDNIKPFTTYLVWVRCIFNKNLLGPFADVLMCRT
What is the function of this protein?
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein.  Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).
What are the official names of this protein?
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, POMGnT2, Extracellular O-linked N-acetylglucosamine transferase-like, Glycosyltransferase-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: SYFA_COLP3
Sequence: MNLDTTTIDSIVAQAEVAIAQASDPTALDQVRVNFLGKKGLFTEQMKGLGKLPKEEKPKMGQVINIAKQAVQKLLTERGELLRAQEIKEKLAAESIDVTLPGRGTQIGGLHPVTRTIARIESFFGDLGFEVKDGPEVEDDYHNFDALNIPEHHPARQDHDTFYFNPKLVLRTQTSGVQIRTMEVEQPPLRIISPGKVYRNDYDQTHTPMFHQVEGLMVDKDVSFTHLKGILHDFLHHFFEEEVEIRFRPSYFPFTEPSAEVDIMGKNGKWLEVLGCGMVHPNVLRSVGIDPEVYTGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y634_METCA
Sequence: MDKRLLEILVCPVCKGGLIYLREQQELVCLADKLAYPIRDDIPVMLDSEARRLSLEEYDALRQRRAAPVA
What are the official names of this protein?
UPF0434 protein MCA0634.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PAIR2_ORYSJ
Sequence: MVMAQKTKEAEITEQDSLLLTRNLLRIAIYNISYIRGLFPEKYFNDKSVPALEMKIKKLMPMDTESRRLIDWMEKGVYDALQKKYLKTLLFCICEKEEGPMIEEYAFSFSYPNTSGDEVAMNLSRTGSKKNSATFKSNAAEVTPDQMRSSACKMIRTLVSLMRTLDQMPEERTILMKLLYYDDVTPEDYEPPFFKCCADNEAINIWNKNPLKMEVGNVNSKHLVLALKVKSVLDPCDDNNVNSEDDNMSLDNESDQDNDFSDTEVRPSEAERYIVAPNDGTCKGQNGTISEDDTQDPVHEEELTAQVREWICSRDTESLEVSDVLVNFPDISMEMVEDIMERLLKDGLLSRAKKDSYSVNKIADPTTPHIKKEVIMQNVSPTEGTKNSNGDLMYMKALYHALPMDYVSVGKLHGKLDGEASQNMVRKLIEKMVQDGYVKNSANRRLGKAVIHSEVTNRKLLEIKKILEVDIAEQMAIDTNAEPGEPERKDHLSGHEMRDGSTMGCLQSVGSDLTRTRELPEPQQNVSMQSGQEASTVDKDPSRTPTSVREQASVCSLESGVLGQKVRKSLAGAGGTQCSQDKRFRKASTVKEPILQYVKRQKSQVQVQVQ
What is the function of this protein?
Essential factor for meiotic homologous chromosome pairing (synapsis) (PubMed:14758540).  Plays an essential role in promoting homologous chromosome synapsis.  Does not seem to play a role in chromosomal axial element formation, sister chromatid cohesion at centromeres or kinetochore assembly in meiosis I (PubMed:16410547).
What are the official names of this protein?
Meiosis-specific protein PAIR2, OsASY1, Protein HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 2.
What are the subcellular locations of this protein?
Chromosome. Chromosome, centromere. Nucleus. Note=During interphase-early leptotene, distributed as numerous punctuate foci throughout the chromatin. Associates with chromosomal axes at leptotene and zygotene (PubMed:16410547, PubMed:21119003). Associates with chromosomal axes at zygotene (PubMed:27436711). Removed from the axes of arm regions when homologous chromosomes have been synapsed (PubMed:16410547, PubMed:21119003). Localizes to centromeres until diakinesis (PubMed:16410547).
Protein: RNJ_CORGL
Sequence: MNDSRNRGRKVTRKAGPPEAGQENHLDTPVFQAPDASSNQSAVKAETAGNDNRDAAQGAQGSQDSQGSQNAQGSQNRESGNNNRNRSNNNRRGGRGRRGSGNANEGANNNSGNQNRQGGNRGNRGGGRRNVVKSMQGADLTQRLPEPPKAPANGLRIYALGGISEIGRNMTVFEYNNRLLIVDCGVLFPSSGEPGVDLILPDFGPIEDHLHRVDALVVTHGHEDHIGAIPWLLKLRNDIPILASRFTLALIAAKCKEHRQRPKLIEVNEQSNEDRGPFNIRFWAVNHSIPDCLGLAIKTPAGLVIHTGDIKLDQTPPDGRPTDLPALSRFGDEGVDLMLCDSTNATTPGVSGSEADVAPTLKRLVGDAKQRVILASFASNVYRVQAAVDAAVASNRKVAFNGRSMIRNMEIAEKLGYLKAPRGTIISMDDASRMAPHKVMLITTGTQGEPMAALSRMARREHRQITVRDGDLIILSSSLVPGNEEAVFGVINMLAQIGATVVTGRDAKVHTSGHGYSGELLFLYNAARPKNAMPVHGEWRHLRANKELAISTGVNRDNVVLAQNGVVVDMVNGRAQVVGQIPVGNLYVDGVTMGDIDADILADRTSLGEGGLISITAVIDNRTGRLLERPTVQTSGFSEDAKSMMGEVTELSETTMNDLAAEGENDPYRMVQQLRRKLSRFVEQKWKRQPVIMPTVIPMTAETTHIGDDEVRASRESL
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J, RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_NOCFA
Sequence: MKDTETRPGRHRAPEPAHPEQPDTTGDTVVTVSGQDWDTVTETLGGAREERIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRTWMQGVTFVTRMDYLSPFYNETAYCLGVERLLGITEQIPERASIVRVLLMELNRISSHLVCLATGGMELGALTPMLFGFRERELILDVFETITGLRMNHAYIRPGGLAQDLPDDGVAKVRELLDLMPKRLRDMEHLLTQNPIFKARTQDIGYLDLTGCMALGITGPVLRSAGLPHDLRKSQPYCGYETYEFDVPTTTGCDCYGRYLIRVEEMKESLKIVEQCLDRLRPGPVMIEDKKLAWPADLKLGADGLGNSPAHIGRIMGSSMEGLIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMCEGGMVADVIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RAB43_MOUSE
Sequence: MAGPGPGDQDEHYDFLFKLVLVGDASVGKTCVVQRFKTGAFSARQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDISKRSTFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLADFREVPLAEAQSLAEHYDILCAIETSAKDSSNVEEAFTRVATELIMRHGGPMFSEKNTDHIQLDSKDIAESWGCGC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  The low intrinsic GTPase activity of RAB43 is activated by USP6NL.  Involved in retrograde transport from the endocytic pathway to the Golgi apparatus.  Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network.  Required for the structural integrity of the Golgi complex.  Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and Mycobacterium.
What are the official names of this protein?
Ras-related protein Rab-43.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: MURG_RICAE
Sequence: MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRSGNIFLFLPRLSIAVLKAIKLLYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYLGKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVRENIRELKVIEMSSRGLTTGSKKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQAALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAQLLEDEKTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKRRKEGHKLLSNLIEEVI
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH10_LACCB
Sequence: MLKPLGDRVIVEVVEEEEQTVGGIVLANNAKQKPQTGKVVAVGEGALTPEGKRLPMAVKVGDTVLYDKYAGSEVKYEGQDYLVLHEKDIMAIA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_XANCP
Sequence: MLKNDRLLRALRRQPVDRTPVWLMRQAGRYLPEYRATRARAGSFLGMAKNPDIACEVTLQPLERFPLDAAILFSDILTIPDAMGLELYFVEGEGPKFRHPVRDADAIHRLGVPDMETELRYVMDAVRLIRRELDGAVPLIGFSGSPWTLACYMIEGGGSKEYARIKAMAFNAPQLLHHLLSTVTDAVIAYLSAQRAAGAQALQVFDTWGGVLSPAMYREFSLPYLTRIAQELERGSGEERTPLVLFGKGNGAYVSELAASGAEAVGVDWTISLADAAERAGGRVALQGNLDPATLYGSPDAIRSEVGKTLDSYAYGNGGSREGHVFNLGHGMSPDMNPDHVGVLVEAVQTLSKR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_HAEIE
Sequence: MTNIQTQLDNLRKTLRQYEYEYHVLDNPSVPDSEYDRLFHQLKALELEHPEFLTSDSPTQRVGAKPLSGFSQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKQLTFCCEPKLDGLAVSILYVNGVLTQAATRGDGTIGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVDLPTTHYARLQWLKSIGIPVNPEIRLCNGADEVLGFYQDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWATAYKFPAQEELTLLNDVEFQVGRTGAITPVAKLEPVFVAGVTVSNATLHNGDEIERLNIAIGDTVVIRRAGDVIPQIIGVLHERRPDNAKPIIFPTNCPVCDSQIIRIEGEAVARCTGGLFCAAQRKEALKHFVSRKAMDIDGVGGKLIEQLVDRELIHTPADLFKLDLTTLTRLERMGTKSAENALNSLENAKSTTLARFIFALGIREVGEATALNLANHFKTLDALKDANLEELQQVPDVGEVVANRIFIFWREAHNVAVVEDLIAQGVHWETVEVKEASENLFKDKTVVLTGTLTQMGRNEAKALLQQLGAKVSGSVSSKTDFVIAGDAAGSKLAKAQELNITVLTEEEFLAQITR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RSMH_PECAS
Sequence: MLENYKHTTVLLDEAVNGLNIRSGGIYIDGTFGRGGHSRLILSQLGPEGRLLAIDRDPQAIEAAKAIDDSRFSIIHGPFSAMADYVAELGLTGQIDGVLLDLGVSSPQLDDPERGFSFMRDGPLDMRMDPTRGSSAAEWLMKAEADDIVWVLKTFGEERFAKRIARAIVERNRTEPMTRTKELASLIAAASPIREKHKHPATRSFQAIRIYINSELEEIERALEGALSVLAPQGRLSVISFHSLEDRIVKRFIRHQSRGPQVPAGLPLTEEQLRSQGGQTLKPVGKKLMPSEAEVAENPRARSSVLRFAERLPA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BIFLO
Sequence: MLRWQTAGESHGEALVAMIEGLPAGVRISTDDIVSALARRRLGYGRGARMKFEQDKVRLLTGVRHGLTLGSPVAIEIANTEWPKWTEVMSADALDHDLPREGRNAPLSRPRPGHADLTGMRKYGFDDARPVLERSSARETASRVALGEVAKQFLDQAFGIRTVAHVVALGGVQTNPDLPLPTPDDLEALDASPVRTLDKEAEARIIERINEAKKASDTLGGVIEVLAYGVPAGIGTYVESDRRLDAALASAIMGIQAFKGVEIGDGFLEASRPGSQAHDEIVVNADGRIDRLSNRAGGIEGGMSNGQVIRVRGAMKPIPSIPKALRTVDVLTGESAQAINQRSDSTAVPAASVVAEAMVRLTLAKYALDKFGGDSVAETRRNLESYLASWPEHMR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ZSC25_HUMAN
Sequence: MLKEHPEMAEAPQQQLGIPVVKLEKELPWGRGREDPSPETFRLRFRQFRYQEAAGPQEALRELQELCRRWLRPELHTKEQILELLVLEQFLTILPREFYAWIREHGPESGKALAAMVEDLTERALEAKAVPCHRQGEQEETALCRGAWEPGIQLGPVEVKPEWGMPPGEGVQGPDPGTEEQLSQDPGDETRAFQEQALPVLQAGPGLPAVNPRDQEMAAGFFTAGSQGLGPFKDMALAFPEEEWRHVTPAQIDCFGEYVEPQDCRVSPGGGSKEKEAKPPQEDLKGALVALTSERFGEASLQGPGLGRVCEQEPGGPAGSAPGLPPPQHGAIPLPDEVKTHSSFWKPFQCPECGKGFSRSSNLVRHQRTHEEKSYGCVECGKGFTLREYLMKHQRTHLGKRPYVCSECWKTFSQRHHLEVHQRSHTGEKPYKCGDCWKSFSRRQHLQVHRRTHTGEKPYTCECGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERLVRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQHRQEPLVQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 25, Zinc finger protein 498.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y065_LEPBL
Sequence: MLDKIKNLSELLSNMGALREKMEDVKKRIASIRVVGDAGAGMVTVTATGEGQIINVFINKQLFDSDDNKMLEDLVMAATNDALKKAKEATAYEFQAASGGLDFSEISKMFGGNFG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein LBL_0065.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: EGH_DROME
Sequence: MNSTTKHLLHCTLLITVIVTFEVFSGGIKIDENSFTLVDPWTEYGQLATVLLYLLRFLTLLTLPQVLFNFCGLVFYNAFPEKVVLKGSPLLAPFICIRVVTRGDFPDLVKTNVLRNMNTCLDTGLENFLIEVVTDKAVNLSQHRRIREIVVPKEYKTRTGALFKSRALQYCLEDNVNVLNDSDWIVHLDEETLLTENSVRGIINFVLDGKHPFGQGLITYANENVVNWLTTLADSFRVSDDMGKLRLQFKLFHKPLFSWKGSYVVTQVSAERSVSFDNGIDGSVAEDCFFAMRAFSQGYTFNFIEGEMYEKSPFTLLDFLQQRKRWLQGILLVVHSKMIPFKHKLLLGISVYSWVTMPLSTSNIIFAALYPIPCPNLVDFVCAFIAAINIYMYVFGVIKSFSLYRFGLFRFLACVLGAVCTIPVNVVIENVAVIWGLVGKKHKFYVVQKDVRVLETV
What is the function of this protein?
Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis.  Neurogenic protein implicated in epithelial development.  Critical component of a differential oocyte-follicle cell adhesive system.
What are the official names of this protein?
Beta-1,4-mannosyltransferase egh, Protein egghead, Protein zeste-white 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.