PharMolix/UniProtQA huggingface dataset:
Protein: RECA_NOSS1
Sequence: MAINTDTSGKQKALTMVLNQIERSFGKGAIMRLGDATRMRVETISTGALTLDLALGGGLPKGRVIEIYGPESSGKTTVALHAIAEVQKEGGIAAFVDAEHALDPTYASALGVDIQNLLVSQPDTGESALEIVDQLVRSAAVDIVVIDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKITGNIGKSGCTVIFINQLRQKIGVTYGSPETTTGGNALKFYASVRLDIRRIQTLKKGTDEFGNRVKVKVAKNKVAPPFRIAEFDIIFGKGVSTLGCLVDLAEETGILIRKGAWYSYNGDNISQGRDNAIKYLEEKPEFSEQIKQQVREKLDKGAVVSANSVAKNNEDDEDEDVEEEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UQCC2_RAT
Sequence: MAALRYRRFLKLCEEWPVDETKRGRDLGAYLRQRVAQAFREGENTQVAEPEACDQMYESLARLHSNYYKHKYPRPRDTSFSGLSVEEYKLILSTDTLEEFQEMNKSVWRKLQEKFAPTRPEEKHRAWTRVLSRPRT
What is the function of this protein?
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).  Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells.  Involved in cytochrome b translation and/or stability.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 2, Mitochondrial nucleoid factor 1, Mitochondrial protein M19.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion inner membrane. Note=Predominantly expressed in the mitochondrial inner membrane.
Protein: RL9_BACCQ
Sequence: MKVIFLKDVKGKGKKGEVKNVPDGYANNFLLKQGLAAEATNSSMKTLEAQKRKEEKDAAAELENAKQLKETLEKLTVELKAKSGEGGRLFGSITSKQIVDAMQKSHNIKLDKRKFEMDDAIRALGYTNVTVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS10_GEOMG
Sequence: MPSQKIRIRLKAFDHKLLDQSVGEIVDTAKRTGARVAGPIPLPTIINKYCVLRGPHVDKKSREQFEIRTHKRLIDILDPTQQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RSMA_RHILO
Sequence: MSIDGLPPLRDVIERHGLQAKKALGQNFLLDLNLTGKIARSAGDLTNTAVIEVGPGPGGLTRALLSNGARRVVAIERDERCLAALAEVSAHYPGRLEVVSGDALKTDFAALASAAGGASGQVRIVANLPYNIGTELLVRWLTVVDWPPFYASMTLMFQREVAQRIVAEPGSDAYGRLGVLAGWRTKARIAFDVPPQAFTPPPKVTSSVVHLEPRATPLPADVKKLGRVTEAAFGQRRKMLRQSVKSLGGEALLERAGIDPTRRAETLSVEEFVRLTNSV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCONB_ASPFU
Sequence: MDAHELSFRDGHGSSTSTMKDGCASAEKPHYLPGDSSFTSVFGPSETVEDVETEPGSTQDKPHSFNTQKPIRENLAGKNVAPFLARHIPEQYAPLGSQGGQPVEISSANSKYCYRHRPDLKCRRQADEPTMDKLQRELETLPQSDQQGIAHAWSIFSAAPAKHRKLILQGIMAQCCFPQLSFISATVRDLIRIDFLTALPPEISFKILCYLDTTSLCKAAQVSRRWRALADDDVVWHRMCEQHIHRKCKKCGWGLPLLDRKRLRESKREIERRAATWDVSKQPAGIEGSSATIETAAAGSKRKPESGKEDTAMVKRQCTSIVSQSEQNEDYFKTRYRPWKEVYKDRFKVGTNWKYGRCSTRVFKGHSNGIMCLQFEDNILATGSYDATIKIWDTETGEELRTLKGHQSGIRCLQFDDTKLISGSMDHTLKVWNWRTGECISTYSGHRGGVVGLHFDATILASGSVDKTVKIWNFEDKSTCLLRGHTDWVNAVRVDSASRTVFSASDDCTVKLWDLDTKSCIRTFHGHVGQVQQVVPLPREFEFEDHDVECENDNVSVTSGDSPAASPQALPGFDGQTSDTPSSAFGPAFDDGRPSPPRYIVTSALDSTIRLWETSSGRCLRTFFGHLEGVWALAADTLRIVSGAEDRMVKIWDPRTGKCERTFTGHSGPVTCIGLGDSRFATGSEDCEVRMYSFQT
What is the function of this protein?
Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
What are the official names of this protein?
Probable E3 ubiquitin ligase complex SCF subunit sconB, Sulfur controller B, Sulfur metabolite repression control protein B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MET30/SCONB/SCON-2 family.
Protein: RNC_MYCS2
Sequence: MTDSHAALLEALGVALPAELLTIALTHRSYSYENGGLPTNERLEFLGDAVLGLTITEELYHRHPDRAEGDLAKLRASIVNTQALADVGRGLTDEGLGAHLFLGKGEENSGGADKSSILADGVESLLGAIYLEHGLTVVREVILRLFGELLDTAPTLGAGLDWKSSLQELTAARGLGAPAYVVTSTGPDHDKEFSATVVIGEAEYGHGVGRTKKEAELKAAASAYKTLDES
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the all rRNAs (23S, 16S and 5S) (Probable).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_RHOPA
Sequence: MVVLVDTVSANPVRPRHPEKAARPDALSPKKPDWIRVRAPTTRGYGETRGIVKENGLHTVCEEAGCPNIGECWDKKHATFMIMGDTCTRACAFCNVKTGMPGALDANEPAYVAEATRKLGLQHLVITSVDRDDLADGGAAHFAATIRAVREACPTTTIEILTPDFLRKDGALEVVVAAKPDVFNHNLETVPSRYLSVRPGARYFHSIRLLQRVKELDPSIFTKSGIMVGLGEERHEVLQVMDDLRSAEVDFLTIGQYLQPTRKHHAVMRYVTPDEFAGYQTTAYAKGFLMVSASPMTRSSHHAGDDFAKLKAARAARAR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PORG3
Sequence: MTTKELFDRICRKRSFLCVGLDTDVKKIPPHLLNEDDPILAFNKAIIDATAEYCVAFKPNMAFYESMGSFGAHSFEKTIEYIRERYPDQFIIADAKRGDIGNTSDMYARSFFEHLKVDALTVSPYMGEDSISPFLSYAGKFTVLLALTSNKGSQDFQMMRDADGEYLFERVIRISQTWDNAGQLMYVVGATQASMLKDIREIVPDAFLLVPGVGAQGGSLEDVAEYGMNAHCGLLVNASRSIIYADNTEGFAAKAAGEAAAMQRQMEIALRAKGLI
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: PTTBC_ECOLI
Sequence: MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANARPKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARHNMKWHEQLISHFAVIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGINLKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAIIIPIVLTSFIYQRKYRLGTLDIV
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in trehalose transport at low osmolarity.
What are the official names of this protein?
PTS system trehalose-specific EIIBC component, EIIBC-Tre, EII-Tre.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UXUR_HAEIN
Sequence: MSHITKIKNWNTNLRKNMENIVNRTYTRIGQLLKQDISQGIYSIGDKLPTEREISEKFGVSRTIVREAMVMLEVEKLVEVKKGSGVYVVRTPESIHMEHSDLPDVGPFELLQARQLLESSIAEFAALQATKKDILNLKQILNREKELLTQNQDDYSADKDFHLALAEITQNDVLVKLQEQLWQYRFNSAMWAQLHSRILQNDYHHLWIEDHQTILSAIQKKNANEARKAMWQHLENVKVKLFELSDVEDPHFDGYLFNTNPVVVGI
What is the function of this protein?
Repressor for the uxuRBA operon.
What are the official names of this protein?
Uxu operon regulator.
Protein: MRFL_HUMAN
Sequence: MDVVGENEALQQFFEAQGANGTLENPALDTSLLEEFLGNDFDLGALQRQLPDTPPYSASDSCSPPQVKGACYPTLRPTAGRTPAPFLHPTAAPAMPPMHPLQSTSGMGDSCQIHGGFHSCHSNASHLATPLDQSVSSHLGIGCSYPQQPLCHSPGASLPPTKKRKCTQALEDSGECRVWACHCRPMTSRSRSSEVQDPDSEGQNRMPTDQCSPALKWQPCHSVPWHSLLNSHYEKLPDVGYRVVTDKGFNFSPADEAFVCQKKNHFQITIHIQVWGSPKFVETEMGLKPIEMFYLKVFGTKVEATNQIIAIEQSQADRSKKIFNPVKIDLLADQVTKVTLGRLHFSETTANNMRKKGKPNPDQRYFMLVVGLYAANQDQFYLLSAHISERIIVRASNPGQFENDSDALWQRGQVPESIVCHGRVGINTDAPDEALVVCGNMKVMGTIMHPSDSRAKQNIQEVDTNEQLKRIAQMRIVEYDYKPEFASAMGINTAHQTGMIAQEVQEILPRAVREVGDVTCGNGETLENFLMVDKDQIFMENVGAVKQLCKLTNNLEERIEELEIWNRKLARLKRLSSWKSSASEASTISKSSRAVSASSPRRAVHKKNNKVYFSGKRQACPNWVFQTLVITLIAVMAFCALTIVALYILSLKDQDRRVPNLPPSNITSSQEPALLPTASSSAPNTSLVTTPASLQVPEITFCEILPCQETYCCPIRGMKEVSSSPVQRQSEEKEFHQRRWSEDKSKSVLARNALSGPDWESDWIDTTISSIQIMEIQQIIDHQYCIQSLQCGSGNYNYNIPVNKHTPTNVKFSLEINTTEPLIVFQCKFTLGNICFHSKRGTKGLESHREISQEMTQGYQHIWSLPVAPFSDSMFHFRVAAPDLADCSTDPYFAGIFFTDYFFYFYRRCA
What are the official names of this protein?
Myelin regulatory factor-like protein.
What is the protein family that this protein belongs to?
Belongs to the MRF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UXAB_ECO24
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKAKGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: NFI_SULIK
Sequence: MVEKHLLEFLEKLQFLISKNVKISHYGIENVKKICGVDIAYKGNLGFSVGVSMDINSGDYNYKSYVGEVNFPYIPGFLFMREAPLMIKAIEGLDCHLLLVDGHGIAHPRKSGIAAVIGVLLDFPTIGVAKSRLTGDLVNESEITYVYLNGEKVGVKFGRYFYSPGNKVDLQDCIELGKRGYPKVLKIADMLTKKIKKE
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_YERE8
Sequence: MSKPIQMERGVKYRDADKMALIPIKTVVTERQELLRKPEWMKIKLPADSSRIQGIKAAMRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIKDMGLRYVVITSVDRDDLRDGGAQHFADCISAIRAKNPTIKIETLVPDFRGRMDRALDILTVTPPDVFNHNLENVPRVYRQVRPGANYEWSLKLLERFKEAHPDIPTKSGLMVGLGETNAEIVEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPAEFDEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGLEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB2_METAC
Sequence: MYRNDVKEISMEQTKIILDENEMPKKWYNVLADLPSPIDPPLDPRTWQPISPDALEPIFPKALIMQEMSSDRYIDIPEEVLDVYRLWRPSPLFRAHQLEKVLKSPAKIYYKYEGVSPAGSHKTNTSIAQAYYNMKEGTERLTTETGAGQWGSALSLACNYFDLECKVYMVRSSFYQKPYRKSLITLWGGNVVPSPSPDTEFGRKILQEQPDTPGSLGIAISEAVEDAIAHENTKYSLGSVLNHVVLHQTVIGAECKQQLAQVEEYPDVVIGCCGGGSNLGGIGLEFIKDRLEGKHSARVVAVEPSACPSLTKGEYRYDFGDTAEMTPLLKMYTLGHKHVPPAIHAGGLRYHGDSPIISKLCSEGLMEAVSYDQQEVFDAAVQFARTEGIVPAPESSHAIRCAIDEALAAKQTGEEKTILFNLSGHGHFDMSSYDKYFSGELM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PG132_VACCC
Sequence: MDKLRVLYDEFVTISKDNLERETGLSASDVDMDFDLNIFMTLVPVLEKKVCAITPTIEDDKIVTMMKYCSYQSFSFWFLKSGAVVKSVYNKLDDVEKEKFVATFRDMLLNVQTLISLNSMYTRLRQDTEDIVSDSKKIMEIVSHLRASTTENAAYQVLQQNNSFIISTLNKILSDENYLLKIIAVFDSKLISEKETLNEYKQLYTISSESLVYGIRCVSNLDISSVQLSNNKYVLFVKKMLPKIILFQNNDINAQQFANVISKIYTLIYRQLTSNVDVGCLLTDTIESAKTKISVEKIKQTGINNVQSLIKFISDNKKEYKTIISEEYLSKEDRIITILQDIVNEHDIKYDNKLLNMRDLIVTFRERYSYKF
What is the function of this protein?
Lipid-bound viral membrane assembly protein that plays an essential role in immature virion (IV) to mature virion (MV) transition (PubMed:29915071).  Functions in both crescent-shaped viral membranes formation and its enclosure to form immature virions.  In addition, participates in targeting mature virion proteins to sites of virion assembly to ensure their proper localization.
What are the official names of this protein?
Virion morphogenesis protein OPG132.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG132 family.
Protein: MURI_SULSY
Sequence: MPIGIFDSGIGGLTVFKEIAASFPKVDLYYLGDTARVPYGNKSKTTIIRYSVECASYLYHNYNVDAIVIACNTASSYALDTLREILPIPVIGVVQPGAESAVKVSKNKKIGVIGTSATIKSNSYFETLKSLDKDLEIYQKACPLFVPLVEEGWIDNEVAKLTVKEYLDDLVKTGIDTLILGCTHYPLLKNTIKGLYPHLNIVDSSVAIVEHLKNIKLNIEETGKRKIFITDESHAFDKLKNMLVGDIKTEKIELSDLCSL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: UNG_GEOSW
Sequence: MAILKNDWAPLLEEEFHKPYYIKLREFLKEEYRTRTIYPDMYDIFNALHYTPYAQVKVVILGQDPYHGPGQAHGLSFSVKPGVPIPPSLANIFKELHDDLGCYIPNNGYLVKWAKQGVLLLNTVLTVRRGEANSHKGKGWEFFTDRVIELVNEKEDPVVFLLWGRHAQAKKELITNPRHHIIEAPHPSPFSAARGFFGHRPFSRTNAFLQKVGREPIDWQIENI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y523_ARCFU
Sequence: MSDNAKTSATDIVQRIISLLTIILLAYFLFKEGLFSVDQRLLSLATIVLLASFLFIIFLVLFKWPLGNLNKKEIRRTIAIVTTSFYFGTLSMVLSGKLELTEEVGALIDGLKWAFMVVVAFYFGSRAVEDALKSKKSAEECPQNTDAEAG
What are the official names of this protein?
Uncharacterized protein AF_0523.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CL3L1_HUMAN
Sequence: MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA
What is the function of this protein?
Chemotactic for lymphocytes and monocytes.  Is a ligand for CCR1, CCR3 and CCR5.  Is an inhibitor of HIV-1-infection.  The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection.  LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
What are the official names of this protein?
C-C motif chemokine 3-like 1, G0/G1 switch regulatory protein 19-2, LD78-beta(1-70), PAT 464.2, Small-inducible cytokine A3-like 1, Tonsillar lymphocyte LD78 beta protein.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AN32A_XENLA
Sequence: MDMKKRIHLELRNRTPADVKELVLDNCRSKEGKIEGLTDEFEGLEFLSTINVCLSSIANLPKLNKLKKLELSDNNISGGLEVLAEKCPNLTHLNLSGNRIKDLSTIEPLKKLEHLKSLDLFNCEVTNLNDYRENLFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDDEDDEDEDDYDEDVPPGEEGEDDDDEEEGEEEEVSGEEEEDEDASREGEEDEGDEEAEHGEKRKRDQDDEGEDDD
What is the function of this protein?
Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex.
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member A.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum.
Protein: TAF9_MOUSE
Sequence: MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKAPAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATSTVQNVLINPSLIGSKNILITTNMVSQNTAESANALKRKREDDDDDDDDDDDDDYDNM
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex.  TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes.  Essential for cell viability.  May have a role in gene regulation associated with apoptosis.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 9, RNA polymerase II TBP-associated factor subunit G, Transcription initiation factor TFIID 31 kDa subunit, TAFII-31, TAFII31, Transcription initiation factor TFIID 32 kDa subunit, TAFII-32, TAFII32.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACT_ACEPE
Sequence: AGFAGDDAPRAVFPSIVGKPKHQGVMVGMGQKDTYVGEEAQSRRGILTIRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKLTQIMFETFNVPAMYVSIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLTKLLMERGYSFTTTAEREIVRDIKKKLCYVALDIEQELTLLPRLEKSYELPDGQVITVGSERFRCPEALFNPGLLGMGSGIARYLFNSIMKCDVDIRKDLYSNTVLSGGTMMFPGIGERMQKEITTLAPSSMKIKVVASPERKFSVWIGGSILSSLSTFQQMWISKEEYDEAGPAIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AGT22_ARATH
Sequence: MQRFAAKRSVQNISVSLWRRCISSTSQAATASVKDSDEFQARLPPFAYTPPPYTGPSADVILSKRKEFLSPSMFCLYRKPLNIVDGKMQYLFDESGRRYLDAFAGIAVVNCGHCHPDVVEPVINQIKRLQHPTVLYLNHAIADFSEALASKLPGDLKVVFFTNSGTEANELALMMAKLYTGCQDIVAVRNGYHGNAAATMGATGQSMWKFNVVQNSVHHALNPDPYRGVFGSDGEKYAKDLQDLIQYGTTGHIAGFICEAIQGVGGIVELAPGYLSAAYDTVKKAGGLFIADEVQSGFARTGNFWGFEAHNVVPDIVTMAKGIGNGFPLGAVVTTPEIAGVLTRRSYFNTFGGNSVSTTAGLAVLNVIEKEKLQENAAMVGSYLKEKLTQLKEKHEIIGDVRGRGLMLGVELVSDRKLKTPATAETLHIMDQMKELGVLIGKGGYFGNVFRITPPLCFTKDDADFLVEAMDYSMSKM
What are the official names of this protein?
Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial, Beta-alanine-pyruvate aminotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNH3_STRTD
Sequence: MGTIVLKMTAEQISVLQKDLASYATATKNPYAFFSAKVDGTSVIAYTSGKVTFQGAKPEILASRFGYQAEPKQSPDGQNLALIGSDEVGNGSYFGGLAVVASLVTPADHAFLKSLGVDDSKNLNDSKIRQIAPLLEEKIPHKALLLSPRKYNEVVGDGKAHNAVSVKVALHNQAIFLLLQSGAKPDKIVIDAFISEKNYQKYLKNERNHFEFPITLEEKAEGKYLAVAVSSIIARNLFLENLDKLSQEVGYTLPSGAGAKSDQVAAKLLQAYGDQALQTTAKYHFANTKKAYQRLK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAVN2_HUMAN
Sequence: MGEDAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQVHQTS
What is the function of this protein?
Plays an important role in caveolar biogenesis and morphology.  Regulates caveolae morphology by inducing membrane curvature within caveolae (PubMed:19525939).  Plays a role in caveola formation in a tissue-specific manner.  Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia.  Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells.  May play a role in targeting PRKCA to caveolae (By similarity).
What are the official names of this protein?
Caveolae-associated protein 2, Cavin-2, PS-p68, Phosphatidylserine-binding protein, Serum deprivation-response protein.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane, caveola. Note=Localizes in the caveolae in a caveolin-dependent manner.
Protein: TTHY_PETBR
Sequence: MAFHSLLLLCLAGLLFVSEAGPVAHGGEDSKCPLMVKVLDAVRGRPAVNVDVKVFKKTEKQTWELFASGKTNDNGEIHELTSDDKFGEGLYKVEFDTISYWKALGVSPFHEYADVVFTANDAGHRHYTIAAQLSPYSFSTTAIVSNPTE
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain.
What are the official names of this protein?
Transthyretin, Prealbumin.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.