PharMolix/UniProtQA huggingface dataset:
Protein: EIF3A_NEUCR
Sequence: MPPPPHQKPENVLKRAHELIGVNQAPAALTLLHEHITSKRSRNVPIASLEPVMLLLVELSVEQKKGKLAKDALYQYKNIAQNTNVATIELVLKKFIELAAEKVTAAQAKADEVQSSIEATTSNIDDLEASETPESILLATVSGEQSRDRTDRAIVTPWLKFLWEAYRTVLDILRNNARLEVLYQSTAMQAFDFCLKYTRKTEFRRLCELLRNHVQTAAKYSAQMHAINLNDPDTLQRHLETRFQQLNVAVELELWQEAFRSVEDIHTLLSLSKRPAKNVMMANYYEKLTRIFLVGENYLFHAAAWARYYNLLRQSAALIASGHSKKADNPACSDADLQRAATFVILSALSIPVISTSRSRGAMVDFDEARKNKNSRLTHLLGMAQAPTRAGLFRDALSKSLLRRAQPQIRDLYNILEVDFHPLSICQKISPILAEIGADAEMQKYILPLQQVILTRLFQQLSQVYETVDLEFVESLAQFPEPFQVTRGTIEKFIMNGNKKGDLAIRMDHATGVLSFDADVFSSAKAVHAGSSAGSAESETGSVQRLQSTPSQIVRSQLTRLAEALYTTCRYIDPSFNEARIKARDEALARAKAGAEKEHQEVLARKEIIQTRKDKASEAQAQKEKENARKKLLQEQALQQAEAARLAEEQKLREAKRLANEREQIKRKEVEALLKDMKLEELQGEDIETLDSNKIRMIKLQQLEREKNSVAEKLRITGKRLDHLERAFRKEEAKKLPEDYAKQRERDLAAYERTKAQTLKEAELKHKADVELKHRLTRLMPFYESFRSDLHERRRDEFEKRRRDAEREMEKQINARRKEAREKRIREKREREERERQLREAEERAAREKEEERKRLEARREELQRLKEEKEKEREKLREIAARQQQREEEAMARRKAEKEKLAATPSAYRPPAAAERTEAAAPPRIALAGNRPSWREREAAKAASGETAAPAPAAAEPVAERPRAAAPPAERTEAAAPPRLALAGNRPSWREREAAKAASGGGNAAAVPERSAPPLRAAAPQRAGSGRPENDRDVPPAEPLKASGAPGKYVPKWRREGA
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_NATTJ
Sequence: MPLSKEQKQEVMEKYKLHEHDTGSPEVQIAILTEKIKQLNEHLKTHQQDHASRRGLLKMVGKRRGLLNYLKSNSADRYLELIKKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CDAS_BACT1
Sequence: MHEWGLSEELKIQTKQMIEIAEKELSIMRNAIDKEDECILCKMEDIHHMLANVQTLAATYYIQAYLSPYTESSSFITTAIQHLSARKHGALIVVERNETLEALIQTGTTLNAHLTAPLLESIFYPGNPLHDGAVLVKNNHIVSAANILPLTKSTEVDPELGTRHRAAIGLSEKSDALILVVSEETGRTSFALNGILYTISL
What is the function of this protein?
One of 3 paralogous diadenylate cyclases (DAC) in this bacteria catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  It has slow DAC activity with ADP as a substrate and may have weak ADPase activity (PubMed:26441857).  Required for efficient spore formation, whereas in B. subtilis, it is required for efficient spore germination.  It is produced under the control of different sigma factors in the two bacteria.  It is also required for parasporal crystal formation (PubMed:26441857).
What are the official names of this protein?
Diadenylate cyclase CdaS, DAC, Cyclic-di-AMP synthase, c-di-AMP synthase.
What is the protein family that this protein belongs to?
Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
Protein: KY_CAEEL
Sequence: MNSKQHCNRCGKQVYPTDKVGPLKDSTFFHQGCFKCYICGTRLALKTYCNNRNDINDKEVYCSNHVPIAGPHDLPMASTNGSGKNLENNNHVKNGNWIDAGLSDMKIAHAMKATQVARPYPKISHEGAKYVVDYDTQTRLELLHRKDEDDLYESFQDKRVREAEEFEKENTEEWEKALAEFAKKYEKGQSNMKKDDLIRQLTIKREKKLETLHTKRKERERHQTAELVDRQAKEMLELFKASRSEYSNLQYPSTPPPPVPPSCSKREIYTTTDYFSSIDEVAIHCARNEVASFTDLIRTLSSGARSDVDVARAIYRWITIKNLNTMIFDDSIQNDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGFSKSAGYQPGYSFDDHRFRNTWNAVFLDGSWRFVQCNWGARHLVNAKDGSHEAKTDGNLRYEYDDHYFMTDSEEFIYEFFPSDHAWQLLPRPLSLLQFERIPFVRSLFFKYNLSFIDNKLESTVYTDKSGAASISIRLPPKGDSLIFHYNLKFFDSEENTISGMSLKRFVMQSVTEDVVTFRVHAPSTRPLLLDIFANSVSSGAYLTGQPIKFKSVCKFKVVCESLQVIMVPLPECASGEWGPAKATRLFGLLPISHPDAIINTGRYVEIRFRMTRPLSEFVASLHRNRTDDRALQACTRSALKGDMVYIQIEFPGEGQYGLDIYTRQDDQLINGKQLLTHCCKYLIHSRNC
What is the function of this protein?
Cytoskeleton-associated protein (Probable).  May play a role in hypodermal cell development (Probable).
What are the official names of this protein?
Lim and transglutaminase domain protein ltd-1, Kyphoscoliosis inactive peptidase homolog ltd-1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AGO12_ORYSJ
Sequence: MSSRGGGGGGRRGGRGGGGGREGGGGGGGGGGRGGQGRGDLGVVGERQGGGRGAGERGGRHDAPRGRGGVAVGAGAGRQQQQPFHAPAPPSGGGGRGGVQVQPNAAARRPVGGGRGGVGVPAPAPAVAVGALCGEMKGKMVVSGGAPPAGQGSSLAAAQGTDNVKREPSQVAAPAPAPPPATLPPSSSKAVTFPARPDVGTIGRRCRVRANHFLVQVADKDIYHYDVVITPESTYRERNRSIINKLVALHKQFLDGRLPVYDGRKSIYTAGPLPFKTKDFVVKHINPLRGNQREEEYKVTIKQASKTDLYSLKQFLVGRQRELPQDTIQALDIALRECPTSVNFTCDRYVSISRSFFSQSFGHGGEIGSGTECWRGYYQSLRPTQMGLSLNIDISATAFYKAQPVMDFAVQYLNIRDVSRRLSDQDRIKLKKALKGVQIVATHWKEKSIRYKITGIPSAPMNELMFDLDGNRISVVQYFKKQYNYSLKHVNWPCLQAGSDSRPKYLPMEVCSILEGQRYSKKLNEHQVTNILRMTCERPAQRESSIIEIVNTNSYGNDDCAKEFGIKVANQLAVVDARVLPTPRLKYHDSGREKVCNPSVGQWNMINKRMVNGGCINHWTCLSFASRMHVNDIRMFCEDLVGMCNNIGMQMNTRPCVDIIQGQQRNIEGAIRNIHRQSSEKLDQQDLTGQQLQLLIVILTEISGSYGRIKRICETEVGVITQCCAPKSLQKGGKQYLENLALKMNVKVGGRNTVLEDALHKKIPILTDRPTIVFGADVTHPSPGEDASPSIAAVVASMDWPEVTKYKCLVSTQSHREEIISNLYTEVKDPLKGIIRGGMIRELLRSFYQETGQKPSRIIFYRDGISEGQFSQVLLYEMDAIRKACASLQEGYLPPVTFVVVQKRHHTRLFPENRRDMMDRSGNILPGTVVDTMICHPSEFDFYLCSHSGIKGTSRPTHYHVLLDENGFKADTLQTLTYNLSYTYARCTRAVSIVPPAYYAHLGAFRARYYMEDEHSDQGSSSSVTTRTDRSTKPLPEIKENVKRFMFYC
What is the function of this protein?
Probably involved in the RNA silencing pathway.  May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
What are the official names of this protein?
Protein argonaute 12, OsAGO12.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: VE4_COPV6
Sequence: MRFTNPLLFPPPVPPEPPDRNSPVTPPRGPVPVPLPPGKGRHGGLDGGRRGSPEGQEDEEDSDEEEAENYPPSRSRPRRGRRRLHNKWDQNINYEPPAAPEDDWEDFCKKLTIPQFLF
What are the official names of this protein?
Probable protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
Protein: PTH_SYNE7
Sequence: MSEDRPTLLVGLGNPGQKYAETRHNIGFMLIDRLAQDWGVKLSEDRKFQGEYGETAVPGLGKIRLLKPTTFMNQSGRSLRAVLDWYKLTPQQILVIYDDMDLPLGRLRLRQSGSAGTHNGMKSIISHLSSKDFPRLRLGISLPRSQSNDRHDATVSHVLGKFAVSEQSLLKQVLDLAQEATETALRSGVETAMNRYNARSLEAPAPVA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_YERPE
Sequence: MTDKLAVNRNTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHPALVSALHQQGETLWHTSNVFTNEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARHYAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLAAVKAVMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSYMHYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGTHGTTYGGNPLACAVAEAALDVINTPEVLNGIEQRHGLFVQALQSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAAAANGLMILNAGPDVLRLAPSLVIELEDIQQGMARLEKAMASVIKG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Acetylornithine/succinyldiaminopimelate aminotransferase, ACOAT, DapATase, Succinyldiaminopimelate transferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y551_METJA
Sequence: MVKRMHCNINLKYGVIMKKDCYTLRISLKPGFINAEQLKAIAYVIENFGDNKAHITTRQGIEFKISPEHLEEVEKILNNVGLNLGSTGNRVRQVVSCIGLECYNAIGDSVSLARRIHEEFEGVWVPRKVKINVSGCPNSCTFHRFCDIGICYRYKITINKEICTNCGKCKDFCDLNAIDWERKIIKDNCTGEGKCTGLCNAFKAERVISIFVGGKGGRIYKEGKHLIDLKNEDDVLFVIDELISLYAKFGKGRMADFVENYGIENLRNNIKELIK
What are the official names of this protein?
Uncharacterized protein MJ0551.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: ISPG_ECOBW
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TDH_ANADF
Sequence: MKALVKSRRAEGIWMVHDAPVPEVGVHDVRIRVRKSAICGTDVHIYNWDEWSQRTIPVPMIVGHEYVGVVDAVGGEVEAFHPGDRVSGEGHVTCGFCRNCRAGRRHLCRHTIGVGVNRPGSFAEYVVIPADNVYRIPDDIPDEVAAIFDPYGNATHTALSFELVGEDVLVTGAGPIGVMAVSIARHVGARHVVVTDVNDYRLGLARRMGATRAVNVAREDLRAVMKDLGMKEGFDVGLEMSGNGRAFRQMLEAMNHGAKVALLGIMPGEEAIDWSQVVFKGLVLKGIYGREMYETWYKMVAMLQSGLDISPVITHRFPIDEFQQGFDVMRSGQSGKVVLDWGT
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_GLUOX
Sequence: MSGFPSDLLAGERYAVCGLGRNGTAVVQALLGMGAEVQAWDDRNADLPAQPNLTVAPLTDLSGMTALILSPGIPHLLPKAHPVADLARAQGIQILSDAEILYRAVRKSGSKAAFIAVTGTNGKSTTTALIAHLFTTAGRPCAAGGNLGTASLALPLLPDDGVYVIEMSSYMLERLDRFHANAACLLNLTPDHLDRHGDMAGYAAAKAHVFDNMGPDDLAVIGMDDDWCRAIASQVASRGVQVVELDADALPPYDGPALPGRHNAQNVGAALTIASHLGLDEAAIRTGLKSFPGLEHRLQKVAECDGVSFINDSKATNAEAVSKALAAYDKVMWIAGGVAKAGGIESLAPFFRHIAQAFLIGQDADVLAATLETHGVPFQQCGTLEKAVPAAFKAALDENIPVVLLSPACASFDQFRSFEDRGSHFLQICDNIVKSGHSGTNPTQKQED
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA8_NAJNA
Sequence: LKCNKLIPLAYKTCPAGKDLCYKMYMVSDKTVPVKRGCIDVCPKNSLLVKYECCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity (By similarity).  Has hemolytic activity towards human erythrocytes (EC(50)=0. 074 uM) and cytolytic activity towards various cell lines (PubMed:26456928).
What are the official names of this protein?
Cytotoxin 8, CTX8.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: LEUC_HAEIN
Sequence: MAKTLYEKLFDSHIVYEAEGETPILYINRHLIHEVTSPQAFDGLRVANRQVRQVNKTFGTMDHSISTQVRDVNKLEGQAKIQVLELDKNTKATGIKLFDITTKEQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKIEVRGKVASGITAKDIILAIIGKTTMAGGTGHVVEFCGEAIQDLSMEGRMTVCNMAIEMGAKAGLIAPDETTFAYLKDRPHAPKGKDWEDAVAYWKTLKSDDDAQFDTVVTLEAKDIAPQVTWGTNPGQVISVNETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKDIKVDQVFIGSCTNSRIEDLRAAAAVMKGRKKADNVKRILVVPGSGLVKEQAEKEGLDKIFIAAGAEWRNPGCSMCLGMNDDRLGEWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAGVFGKFVDIRDVTLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CYSI_NITOC
Sequence: MTHDLQQKSKLSAVEKIKAKSRYLRGTIQEGLADLATGAVVEEDTKLLKFHGTYQQDDRDLRTERMRQKLEPAYSFMVRVRMPGGVCMPKQWLQLDELARKYANNSLRITTRQTFQFHSVVKRHLRSTIAGINEALLSTIAACGDVNRNVVCHNNPYLSPLHKTVYEWSKRLSNHFLPQTQAYHEIWMGKEKVAGTLPENEEPIYGETYLPRKFKIGITIPPNNEIDVFSQDLGLIAIAKGSRLVGFNICVGGGMGMTHSEPSTYPRLGDVIGFCTPSQLLEVAENILKIQRDFGNRCDRKQARLKYTIDSRSIDWFKAELNQRLGWDLEPARPFHFESNGDHFGWVEDSKGRWHLTLFLLSGRIKDTLDQPLMTGLREIAKIHKGDFRLTTNQNLTIANISKTNKPRIEALLEKYRIPMPERFSPIRQHAMSCVALPSCGLAMAESERMLPGFLARLEAVVEKAGLADEPITLRVTGCPNGCSRPYISEIALVGKSLGRYNLYLGAGFAGQRLNKLYRESLTEDEIIATLSPLFEHYARERQQGEHFGDFVVRAGYVDEVRAGREFHEVRSEKAVQSA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: 1A_OLV2I
Sequence: MDSAALEKMTGAKFPAVQGVIEEFSRDRVQNVLGDMRSRQVIKYAVGLSEASVQELRFNWPCFTWEEESVPLPPHPFAAYSRRAFTRWAIAQCGPVPIKDFGGNWFLHWQWQTGVHSCCPLLNPRDGAHQTRRELNMESYLRTHGPKYDKFNELSRPDLCHHRAEDCSVRAKAALSVDSAYDMGLKNTCKAMHRAGIELLHGNILFDPDMLIEAKMEGFVAGMNYHWKKTRRSTGLMSSFLEMGSSLFGVSNSSKEGEGHHDLKIKMGSSSTHMVPADWEISYHFRDDCVLGYTHNLADVLSIATGSYVKVGNTFYELERTGLKSGMLMYTITACKGLYDRASARSTPLSAKASTVIINGMSYQVGEKLDPISFPYLAASFYMQAQKAVFEVQQVVDLHTPNRNLWSWFKKKFELKAHAFLFALGLRDSHDEWLLDQIEFELNETVCTLPGEFLEPVSEVERLDAALEDWRRDRERLNGKSVENLKTLTVLVELAKKLGISAYEVLNSHQNESERPKDQWHVEAALFEAVELERAHWKMLTAEAQAMSLQDPLSREAKSKGWSYESSDSLPCAYAYVFSEGRFVKPADLKKKTRVLVSPSMQIMNQIRMAESLEKAIAMNVKSCKKTWIDGVAGCGKTYEIVHTADIFKKDDLILTANKKSQEDIFSQLKPGTDCAKRIRTVDSYLLKPDVQAKRLFIDEAGLVHPGKLLAAMRFAECDDCLLFGDSEQIPFVNIVESLQPAKFLKLEVDAREVRETTYRCPADVTATLATLYKKKKIVTKSKVLKSVTSKSLASASAVSGLDPHSWHLTMYQADKAELVRVARTNQMDDVWIKEHIKTVHEAQGISVPHVKLYRFKTFDQPLFDAAHAEAYRLVAISRHTQSFTYIGVNQHLCKADRMLKFVICQIP
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: PANB_STAAS
Sequence: MKTVSQLIDMKQKQTKISMVTAYDFPSAKQVEAAGIDMILVGDSLGMTVLGYESTVQVTLADMIHHGRAVRRGAPNTFVVVDMPIGAVGISMTQDLNHALKLYQETNANAIKAEGAHITPFIEKATAIGIPVVAHLGLTPQSVGVMGYKLQGATKEAAEQLILDAKNVEQAGAVALVLEAIPNDLAEEISKHLTIPVIGIGAGKGTDGQVLVYHDMLNYGVEHKAKFVKQFADFSVGVDGLKQYDQEVKSGAFPSEEYTYKKKIMNEVNNND
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_VIBPA
Sequence: MLNKQTLISIEDALPGREQPMQIEDCHFVNQSSLTAPLAHHQQQILLGMGCFWGAERLFWQLDGVVSTSVGYAGGFTPNPTYEEVCTGKTGHTEVVRVVFDERVISLAQLLAVFWEKHDPTQGMRQGNDLGTQYRSAIYTYSQDQQEIADKSKLQYQQALEAELRSTITTEIVPAGPYYFAETYHQQYLAKNPDGYCGIGGTGVCFPPSLQG
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: Y43_BPR18
Sequence: MTAITPQEYMASLKEKYNLSATETLFDLPENLQLKFQVEFQKLIHPEQKHFTAVVKSINADGMTIFHRQIVLI
What are the official names of this protein?
Uncharacterized protein ORF43.1 in regA 3'region.
Protein: AROA_MAGSA
Sequence: MIMAKPLSSRRAAPLAGSAPVPGDKSISHRALMLGALAVGESVVTGLLEGDDVLRTAACMRALGAEVERRDDGSWRLFGRGVGGLMEPADVLDMGNSGTGARLLMGLVATHPFTCFFTGDGSLRSRPMRRVIDPLSRMGARFVSRDGGRLPLAVTGTAQPTPITYELPVASAQVKSAIMLAGLNTAGETTVIEREATRDHTELMLRNFGATVRVEDAEGGGRAITVVGFPELTGRPVVVPADPSSAAFPVVAALLVEGSEIRLPNVGTNPLRTGLYQTLLEMGADIRFDHPRDQAGEPVADLVVRSSRLKGVDVPAERAPSMIDEYPILAVAAAFAEGTTRMRGLGELRVKESDRLAAMARGLAACGVAVEEEKDALIVHGTGRIPDGDATVTTHFDHRIAMSFLVMGMASARPVAVDDSEAIDTSFPAFVELMNGLGAKISGDNP
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_COXBU
Sequence: MTATITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGKGVLQAVENVNGPIRDALLGQDPRSQEEIDRIMIELDGTENKANLGANAILGVSLAVAYAAANNADLPLYRYLGGDGGPFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAEALRYGAEVFHALKKRLVSRGLMSAVGDEGGFAPDLPNNEAAFELILEAIEDANYVPGKDIYLALDAASSELYQNGRYDFENNQLTSEEMIDRLTEWTKKYPVISIEDGLSENDWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLATVGLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIERELNDQAPYAGKEAFLFNRK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RS18_PROMT
Sequence: MTNSLFKQKLSPIKPGDPIDYKDVELLKKFITDRGKILPRRLTGLTAKQQRDLTTAVKRARIIALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HEM6_SHIB3
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNDGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_PSEAE
Sequence: MSFDLASRLASRRAEDLYRQRPLLESAQGPDVVVDGQPLLAFCSNDYLGLANHPEVIAALRAGAERWGVGGGASHLVVGHSGPHHELELALAEFTGRPRALLFSTGYMANLGAVAALVGKGDTVLEDRLNHASLLDAGLLSGARFSRYLHNDPASLAARLDKAEGNTLVVTDGVFSMDGNLADLPALAAVAQARGAWLMVDDAHGFGPLGASGGGIVEHFGLGQEQVPVLIGTLGKGFGTAGAFVAGSEELIETLIQYARPYIYTTSQPPAVACATLKSLELLRRESWRRQHLAALIARFRHGAEALGLTLMDSFTPIQPILVGGSRQAVALAGMLRARGIMVGAIRPPTVPANSARLRVTLSAAHSEAQVDRLLEALGESWRQLSSSLLAEIEAEEGDDA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: JAL43_ARATH
Sequence: MLIYNADSVVFLFSLFLQFEINHLQDEHLESVDAYYNKKSYGLQAIQFKTNFRTSELMGYSYECTMFTLAVKGKKIIGFHGSDNVHIYSLGAYFTSITPTRLEVKGGMGGKKWEDGFDHDNVSKIQVLGGFEGILYIKVDYIKNGKLETGLIHGDSGGDGFLQKMEINQSKNEYLVYVEGYYDDASETIQGLHFQTNLNNPVMMGYKKGRKFLLASNGNKIIGFHGYADKSLNSLGAYFSRATPNKLECQGDCRGMSWDDGCNYDGVRKVFVDGIGNEIYTVRFEYDNGGKVEKTPYRRDVKNEKEFVLDYPNEFITSVEGTLAAPKSVNITWITSLTFKTSKKRSSPTFGSASSRKFVLEKNGSPLVGFHGYNSVGNTLNSLGAYYRPIPPTPDVEKLKAQGGVEELLGMMVFELDPLERITSVEGTYDDKIGGITMLRFKTNKKDSPYFGFGTLPSFVLHKDNHQIVGFHGKSSNMLHQLGVHVLPNGFKFVS
What are the official names of this protein?
Jacalin-related lectin 43.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: Y059_ABVP
Sequence: MYLFYVLLSSLFLSALIYVIGKSHPNLFMFISLFVNVVTILYLVFKDYGQYIIAKPINT
What are the official names of this protein?
Uncharacterized protein ORF59.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: VIF_SIVTA
Sequence: MEREKLWVTRLTWRVSGEHIDKWKGIVKYHMRNRLQDWTYLMHYQCGWAWYTCSRFLIPLGGEGKIVVDCYWHLTPEQGWLSTYAVAISFENWQNTYKTEVTPDVADHMIHCHYFPCFTDRAIQQAIRGESFLWCTYKEGHVAENHWGQVRSLQFLALTVYTDFLRNGRRKRFQGKKTRMVRNLGSQQGAVGRMIKRHGSRTQSGSTTPFWERTPLPSMELLSGRRGKEWGTNDRKGL
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=Seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).