PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_BURP6
Sequence: MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YGFZ_BUCBP
Sequence: MNNELIEYNLHFSKTIKLTFLKDWSFITVTGKDCFNYLQGQITYNLKLLKSNKHIICSHCTIDGKVLSILRLFMHNDGYAYILRKSTSKFQINELKKYSIFSHVNICQKKDIILLGIMGREARTKLLQIFKNIPHERDSVYQENDVIILKYDQPHERYLIIIKKHNLILNKILSLVDKIYHHKIWLALEIASNFPIIDYNINKKFFPQSLNLEKLNGLDLKKGCYYGQEMIAKIHFKKLNKHYLHWLSGYSYPIPKIGDNIEQKKNKNFSSCGWILSVVKLSTTKIWIQAVLKHYNHYKTNVFRIKNKINSFFYITDE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIVIB_LACRG
Sequence: MAWLRKKEQQSDPLTPWQQYQARQQQTPRHDRRQKPKLDVNLPKIQTLRRRKLVKNLVLILLPLLLLLGVFGYFASPLSKVGLVSVQGVTTVPDQQVINATKLSDDDLMLSVAFHKNAIAQRVQKSLPEIKTASLTIKGFNRIIIKTSEYQTVGYVYQKHAYHKILVTGEVLAAGTQTPVTTYPVFSGFTAKELPQMITLLKQFPAAIRRDISEIDASRGDANPNQIALNMNDGYRIIADTRTIAKKIKYYPAIVSQVKQKGVVDLEVGAFWRPYSSSEKSSND
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: PG145_VARV
Sequence: MSLLKMEYNLYAELKKITCGQSLSLFNEDGDFVEVEPGSLFKFLIPKGFYSSPSVKTSLVFETLTTTDNKITSINPTNAPKLYPLQHKVVSEVVSNMRKMIKLKRPLYITLHLACGFGKTITTCYLMATHGRKTVICVPNKMLIHQWKTQVEAVGLEHKISIDGVSSLLKELKTQSPDVLIVVSRHLTNDAFCKYINKHYDLFILDESHTYNLMNNTAVTRFLAYYPPMMCYFLTATPRPSNRIYCNSIINIAKLSDLKKTIYAVDSFFEPYSTDNIRHMIKRLDGPSNKYHIYTEKLLSVDEPRNQLILNTLVEEFKSGTINRVLVITKLREHMVLFYKRLLDLFGPEVVFIGDAQNRRTPDMVKSIKELNRFIFVSTLFYSGTGLDIPSLDSLFICSAVINNMQIEQLLGRVCRETELLDRTVYVFPNTSVKEIKYMIGNFVQRIISLSVDKLGFKQESYRKHQESDPTSVCTASSREERVLNRIFNSQNR
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA.
What are the official names of this protein?
Transcript termination protein OPG145, 56 kDa abortive late protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
Protein: NTF2_ASHGO
Sequence: MSMDFSALAQQFTEFYYNQFDTDRSQLGNLYRDQSMLTFETSQLQGAKDIVEKLVSLPFQKVQHRITTLDAQPASPNGDVLVMITGDLLIDDEQNAQRFSQVFHLMPEGNSYYVFNDIFRLNYSA
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSC_ECOLI
Sequence: MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIHYLETPPTRDELVKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLGTRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK
What is the function of this protein?
Involved in resistance to arsenate.  Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase, Arsenical pump modifier.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.
Protein: DTD_CLOBL
Sequence: MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1847_ARCFU
Sequence: MPSHCEGVSISSKEAKVLIKEHTCLVAIPILESGCVITGVDVSESELVWSIICDDEGFIALLENLEGVDFELIYKGKPPARTR
What are the official names of this protein?
Uncharacterized protein AF_1847.
Protein: SFXN2_BOVIN
Sequence: MEADLSDFNIDAPRWDQCTFLGRVKHFFNITDPRTVLVPERELDWAKVMVEQSRMGTVPPGTQVEQLFYAKKLYDSAFHPDTGHKMNVIGRMSFQVPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMAVSYITATTTAVATAVGMNMLTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNHNEIGHSRRAAAIGITQVVISRITMAAPGMILLPVLMERLEKLRFVQRVRVLHAPLQVLLSGCFLIFMVPVACGLFPQQCELPVSYLEPELQDTIKAKYREPVPHVYFNKGL
What is the function of this protein?
Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria (By similarity).  Involved in mitochondrial iron homeostasis by regulating heme biosynthesis (By similarity).
What are the official names of this protein?
Sideroflexin-2.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: PYRE_DICNV
Sequence: MLAVYQTRFLEAALAADALKFGEFTLKSGRHSPYFFNAAAFCNGKLLSVMTEAYAAVIAELHETCAIDVLFGPAYKGIPLVAGIAQALFHRYDINLAWAFNRKETKTHGEGGNIVGASVAGKKVLLVDDVLTAGTAVRQSLALLAQEQAMPVGLVIALDRQEKVGDSNLSALKQFSVENQLQTRAIITLDDLMTFVKESGKPAVLEKMQAYRKIYGISEAD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PYRB_METS3
Sequence: MIKIFELKSIISIKDFERKDIDYILDEASKLEDIAKSKECCDELKGKILGLMFFEPSTRTRLSFETSMKRLGGNCIGIENTRSCSVSKGESIADTAKMFEGYSDALVIRHELEGVSKFISDIVDVPVINAGDGAGQHPTQTLLDLYTIKKELGQIDNLKIALVGDLKFGRTVHSLSNALGLYDNVELYFVAPKELRMPQEVLHDLNKKNIPYTEVDSIEEIIDKVDVLYVTRIQKERFGDLDEYLKIKGAYIVNKKMLEGKDVIVMHPLPRIDEIATDLDNTKHNKYFNQAFNAVPVRMAILKTLIKNNPKWNHIE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: AROB_PASMU
Sequence: MLCVNVELKERRYPIYIGSGLLSDEKCYPLKSGDKVMIVTNPTIAQYYLSQVTDTLVKKGCLVEHVVLSDGEQYKTLDSLNLIFTALLQGNHGRDTTIIALGGGVIGDVAGYAAASYQRGVRFIQIPTTLLAQVDSSVGGKTAVNHALGKNMIGAFYQPCTVIIDTLTLNSLPKREINAGLAEVIKYGAILDLPFFTWLEQNIDSLVARDPDNLQTCIARCCQIKADVVARDETEKGDRALLNLGHTFGHAIETHLGYGHWLHGEAVAVGMLMAAVLSEKLGNLTKTDVARLERLLARANLPTVSPDTMQPEDYLPHMLRDKKVLAGKLRLVLLASLGQAYVATDTDPALVLDAIRCCTQVN
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ECOSM
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: EFG_STRPG
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEKITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_CLOBK
Sequence: MRTIAVLTSGGDAPGMNAAIRAVVRTGLEKGLKVMGIQRGYNGLINGEIFEMDTHSVSDIIQRGGTILRTARCEEFRTEQGREKAAKILKAFGIDGLVVIGGDGSFHGAQLLSKLGINTVGLPGTIDNDLAYTDYTIGFDTSINTVLDAINKLRDTSTSHERVSVVEVMGRNCGDIALYTGVAGGAESIIIPEKEYNADKLCKQILQGKLKGKMHNLVLLAEGVGGANELAKYIEEVTGIETRSTILGHIQRGGSPTCMDRILASRMAYKAVELLISGKSSRVVGIKNGKIIDMDIDEALAVERSFDQELYDIATILSK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM3_HHV2H
Sequence: MFGQQLASDVQQYLERLEKQRQQKVGVDEASAGLTLGGDALRVPFLDFATATPKRHQTVVPGVGTLHDCCEHSPLFSAVARRLLFNSLVPAQLRGRDFGGDHTAKLEFLAPELVRAVARLRFRECAPEDAVPQRNAYYSVLNTFQALHRSEAFRQLVHFVRDFAQLLKTSFRASSLAETTGPPKKRAKVDVATHGQTYGTLELFQKMILMHATYFLAAVLLGDHAEQVNTFLRLVFEIPLFSDTAVRHFRQRATVFLVPRRHGKTWFLVPLIALSLASFRGIKIGYTAHIRKATEPVFDEIDACLRGWFGSSRVDHVKGETISFSFPDGSRSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIMGFLNQANCKIIFVSSTNTGKASTSFLYNLRGAADELLNVVTYICDDHMPRVVTHTNATACSCYILNKPVFITMDGAVRRTADLFLPDSFMQEIIGGQARETGDDRPVLTKSAGERFLLYRPSTTTNSGLMAPELYVYVDPAFTANTRASGTGIAVVGRYRDDFIIFALEHFFLRALTGSAPADIARCVVHSLAQVLALHPGAFRSVRVAVEGNSSQDSAVAIATHVHTEMHRILASAGANGPGPELLFYHCEPPGGAVLYPFFLLNKQKTPAFEYFIKKFNSGGVMASQELVSVTVRLQTDPVEYLSEQLNNLIETVSPNTDVRMYSGKRNGAADDLMVAVIMAIYLAAPTGIPPAFFPITRTS
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RS7_CARHZ
Sequence: MPRRGPVPKRDVLPDPIYGSKLVTKLINKTMVDGKKSLAEKICYRAFDIIREKTGRDPLEVFEEAMKNVMPVLEVRPRRVGGANYQVPVEVRPERRQSLAIRWIVNYARERNGRSMEEKLAAEIMDAANGVGGAVKKKEDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: JMJD4_DANRE
Sequence: MDRETFHSCSSLVKLPRQIHQQHCSSHFIEYIEREIPYSKFFKNYLIPNQPCMFSKKFTEEWNCRKKWVTAEGKPNLQRLLHEFDETPVPVANCSVKEYNANPKQIMPFKEFIQYWRESIQNGHSSPKGCLYLKDWHMQRNFPEHNIYKTPIYFSSDWLNEYWDTIEVDDYRFVYMGPKGSWTPFHADVFRSYSWSANICGRKKWLLYPPGQEDFLRDCHGNLAYDVTAPILQDKGLYAQFEEACQPLEIIQEAGEIIFVPSGWHHQVYNLEDTISINHNWLNGCNLDIMWQFLQDELSSVQREIEEWRDTMDTWHQHCQVIMKSCTGIDYAEFASFLKTIANNRISFLNSSPRNADSCQDLLAESLCALGPHHAAFDLQRVLHIFEIMLNNEDFKRLDPATLSFKPEDLLQEIREAIRTIV
What is the function of this protein?
Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1.
What are the official names of this protein?
2-oxoglutarate and iron-dependent oxygenase JMJD4, JmjC domain-containing protein 4, Jumonji domain-containing protein 4, Lysyl-hydroxylase JMJD4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAP_GLUOX
Sequence: MSDSFSARLEAAVSALPARFPGPGGAVAVLKDGEVLVRHGWGYANVERRIPFTPSTLFRMCSITKQFTCGTLLDLYDDPSELDADVDARLPQLDEPSPGMLHLAHNQSGLRDYWAVAMLHGAPIEGYFGDREARRVIDGTRTLQFQPGTSYSYVNQNFRLISDILQDRTGRSFAELLQTSIFNPVGMERAILAAETRAMPDGTVGYEGSVESGFRPAINNIWWTGDAGLGASLDDMIAWERFIDETRDAPDSLYRRLTVPVTFSDGQPAPYGFGLQRTKMFGRDVTMHGGALRGWRSHRLHVASERLSVVVMFNHMSAAQVASAQILAAALGVPYEPERSTQQPTALYGTYLERETGLSARIEPAPGGAKLRYLMVPELLEGISATRAEAGSVVVKAQETAEGAEAVMERPGENRTSILARCDETPGEDIAELAGVYRCEELDEAEVTIELAGGVVYGGFSGILGDGRMEMLQRLAKDVWVLPCPRALDHTAPGDWTLAFERQGGSVTAVRVGCWLARDLMYQRV
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
Protein: COAX_ACIAC
Sequence: MTFLAIDVGNTRLKWAMYDAPKPGAAVLAHGAEFLDHIERLADSAWAGLPAPTRMLGCVVAGDAVRRRVMEQMEWWDVPSHWVVPSAEEAGLVNGYDHPTRLGSDRWVAMIGARHRLLRQGPARPLVVVMVGTAVTVEAIDAEGRFLGGLILPGHGIMLRALESGTAGLHVPTGEVKLFPTNTSDALTSGGTYAIAGAVERMVQHVIQHCGEEPACMMTGGAGWKMAPSMTRPFDLIENLIFEGLLAIAAERFR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBTP2_HUMAN
Sequence: MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR
What is the function of this protein?
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:11163209, PubMed:10805775).  Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached (PubMed:10805775, PubMed:27380894, PubMed:9659902).  Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription (PubMed:10805775, PubMed:27380894, PubMed:9659902).  Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B) (PubMed:11163209).  Involved in intramembrane proteolysis during bone formation (PubMed:27380894).
What are the official names of this protein?
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50A family.
Protein: CYOE_SHEB5
Sequence: MAKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLGIAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAVTNEFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVLVGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLWN
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KANJ_STRKN
Sequence: MALAAPPGELTLALTPDDKTLDPASLDRALAILAEHGILVLTGMLRTRLTDQLRTAMLDDLPEVLRQQDVPTNFVPGHVQQDPPVRESLLFPDVLLNPVVYQITHAVLGADARNAVYSGNMNLPGSHEQPVHLDEPHLWPGISHPPYCLCVDVPLIDFTLENGSTEYWPGSHVLNPDECYDERGCVLPAELERRRAVAPPVRFPIPVGSVVIRDGRLWHRGVPNLSAAPRPLLAMTHYTEWFDMPPIQLPDTVKSWVDGSDRHTHAHFVAGDVDHLTGDHPFAVR
What is the function of this protein?
Mediates the conversion of kanamycin B into 2'-dehydrokanamycin A during the transformation of kanamycin B to kanamycin A.
What are the official names of this protein?
Kanamycin B dioxygenase, Kanamycin biosynthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: YBEY_HELHP
Sequence: MSIMPTLDMDKDTFTQVGYLYNLLDKIGHLGLFERDLSCYMLEVLAVDSQNMREINFAHRAKNSTTDVLSFPLDVSEGADSHILAKQMKICLGSVVINYELAQKVAKQRGHSTQDEISLLFIHGFLHILGYDHEVDNGEQRALEQKIIESLGLKESLIVRNTT
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_KORVE
Sequence: MENELVSKVKAPVPGNQTNTLNEAKCPVGAHTLAGARSNANWWPNQLNINILHQHSPLSDPMPEGFNYAEEFKTLDLDAVVKDLRHLMTDSQPWWPADYGHYGPFFIRMAWHSAGTYRIGDGRGGAGSGEQRFAPLNSWPDNGNLDKARRLLWPIKQKYGRKLSWADLMVLAGNVALESMGFKTFGFAGGREDVWEPSEDIYWGPEGKWLDDKRYSGERDLENPLGAVQMGLIYVNPEGPNGKPDPAAAAVDIRETFARMAMNDEETVALIAGGHTFGKTHGAGVPTEYVGPEPEGAGIEEQGLGWKNKLGHGHGYHTITSGLEGAWTTNPIKWDNGFFDNLFGYDWELTKSPAGANQWTPKNGAGKDTVPDAHDKTKRHAPFMATTDISLKVDPIYGPISKRFHEHPQEFADAFAKAWYKLTHRDMGPLPRYLGKLVPKEPQVWQDPVPAVDHELVNDSDVAALKAKLLASGLTVSQLVTTAWAAASSFRGSDKRGGANGARIRLTPQKDWEVNQPKELAKVLPVLEKIQHDFNAQGGKKKISLADLIILGGCAAVEEAAKKGGHSVKVPFTPGRTDASQEHTDVKSFSVMEPKADGFRNYHQKGQPRPAEEMLVDKAQLLRLTAPEMTALVGGLRVLGANYGHSKHGVFTSHPETLTNDFFVNLLDMNNRWQPSGADGVYEARDRQGDHVKWTATRVDLIFGSHSQLRAFAEVYACNDAKEKFVHDFVAAWTKVMNLDRYDLAKKKAAAN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: FBK66_ARATH
Sequence: MTLTISDLPRDLKKKIFSRIPLRYVRALRLTCKEWETLIKSRSLKIDEEESQMVALMDYNLCLMSKSFNGGDPSTEIKGKLTCFDEQVKVSMLFHCEGLLLCILKDDNTKVVVWNPYLGQRRFIQVRFSHIPGGWDQFSYALGYYKNNNMMKSFKLLRFFDYFYTSNDFVFYEIYDFDSGLWKTLDVTPYWRIRFFDDIGVSLKGNTYWCAKERKPEWNADPFIIVDHIICFDFTSERFGPLVPLPFRAMKESLVTLSCVREEKLAALFCRDVVVEVWITTTIEFDKVSWSKFLTFGVRDCPMIYSCTGSFFIDEVNKVAVIFGQPLKRDKVFIIGEAGQVRDVDLGEPAHQDSWLYVCPYVPSLVKIKQPPGCKRRRQSSSENRRYKRNMMRLVELEKYHIAMEPKRGDKTI
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g22870.
Protein: CS111_CANGA
Sequence: MQSVNIVSTNYSRYGVSVYDRLYRKDKNVSAKHRPSSTGVYGHDASTVDHASRSNNNLNLTRSTSAISESDDVATISTNNSRRSVIKRKYKSLITASSKKLITKLYEHGSNSDSFSIFSHKTSQSHHPAQRLGTEEDLIINDLFKRKEISDLPDEVLRNILSNVKDDQRTLVNCLYVNKAFYNATKPTLYERPKFTSTYRVAQFVTSIRTNPQNGLYVRELDLSKLKNGSLNGKSTSNTGVVADSPDVDEYNPMRTRTGSVTSFTSVTSTANSNTALSITTNNKDVALAGWRDWRYRHDPLYSSPVLNSYNAKRTVSRAPSIKSSHSSSSLTLFPGLKSKESFAQLSEGKSSDNGNNGKRQRSNSSVSSITNSLMSSLYNGSHISLNTTLSGSDNNSSKTQSKGKSSSSPGNPNDSSGEQDSIISSSSQIDTNTFGMTSSKSTSSTSNWFRMKLHGNGTRKLRLRSNKAISSKKDEQQNEESAQTAQKIETPIIKRTEPFSTPHPYTNKFLLKYAQYKDLPLGYILHILDHCPYLYILDLSNLTLCTDFEIIEGRRYKGRKQRFGSSRALPVVQESVISTDVPNDLDVIYLTDSSKTYEYYDRLRNTNKHKRSSSSNNLWSIPNQGWSDAPAPIGSHKNDLRRTHSQTIGRSNVELRKLNASEIFEHIATNQKSAYNTHLRVYMKNVLWCTQDMVKSFVLENFDQQAENLGEDKSSEMFIHDMNFSFENSGLNRNFVWTCEGNLQEFIAMVVLDEVNRKDDLEIENLFNIKAERILTPTNGPERAPEVHYISNVFTVSYGFQSNKKREMKFRVTILKTDTPMYFSIKKLADDYTSVVIKLQTNKNVALHGSETADIITTDQGSVLPEDVPEDNNADDTNNGENTIAQPFSNDPKERIERITQEIVARLKDLRGSDLRRNIGENNYVRERFLL
What is the function of this protein?
F-box protein probably involved in ubiquitin conjugation pathway.
What are the official names of this protein?
F-box protein COS111.