PharMolix/UniProtQA huggingface dataset:
Protein: ACCC2_BACSU
Sequence: MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDAPHTKAATEAYLIGESRVSESYLNIERIIKTAKKAKADAIHPGYGLLSENSRFAERCKQENIVFIGPSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKASAGGGGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTVHLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQKQNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIYAEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAIEKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxylase 2, Acetyl-coenzyme A carboxylase biotin carboxylase subunit A 2.
Protein: ATPF_DESVV
Sequence: MKGLKITAAAGAMTLFFASMAYASGDSGHGPDWGNFAFRVVNFVIFAGIIWKAAGKKIVGFFTGRRQGIEQELNDLETRKTEAKKQLAEVERRIANLESERQAILADYRAQGENIKAAIIDKAEKSASLITEQAKRTADNEIKAAIDAMRAQMADEIIVAAEKLLAEKLTANEHEKLIDKYLTKVVLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PXPA_GEOKA
Sequence: MRTIDLNCDFGESFGVYRLGQEEILSYVTSVNIACGFHAGDPLVMRRTVQLAIQHGVAIGAHPGFPDLFGFGRRAMAVSPEEVYAYVVYQIGALAAFVKAEGGVMTHVKPHGALYNMAAKDAALAEAIAKAVHDVDPMLVLYGLSGSELIRAGRACGLRTASEVFADRTYQADGSLTPRSDPRAIIADEDEAVTQVLMMIRDRRVRSVQGTDVAIEADTVCLHGDNEQAVRFAKRLYQALQNEGIAIQAPRREERR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: LOLD_EHRCR
Sequence: MSTVFALANIYKSFGRNKEVPVIVNATLQIKKGEIVALIGKSGSGKSTLLHIAGLLDTPSSGSILLNNIECTDKTSDKDKTYLRRHFLGFIYQFHHLLQEFSVLENVMLPQIITGKSKSIAKKNAMEILERVRLQDKLSMPISQLSGGERQRVAIARSLINCPLIVLADEPTGSLDNNTALEVFSLLQEYAKEKNIAILLATHNYSLAQKACRIVKIDSGILRSYSIDESGFNKI
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TNAA_PASMU
Sequence: MENFKHLPEPFRIRVIEPVRRTTRSYREEAILKAGMNPFLLDSEDVFIDLLTDSGTGAVTQEMQAAMLRGDEAYSGSRSYHALANAVKEIFGYEYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVVFSNYFFDTTQGHSQINGATVRNVYTKEAFDTSVNADFKGDFDLEKLEQGIQEVGAENVPYIVCTITCNSAGGQPVSLANMRAMYEIAKKYDIPVVMDSARFAENAYFIQQREPGYKEWTIEQITYESYKYADALAMSAKKDAMVPMGGLLCFKDKSMEDVYNECRTLCVVQEGFPTYGGLEGGAMERLAVGLRDGMRQDWLAYRINQIEYLVNGLEAIGVVCQQPGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKQVKENAENIKGLTFTYEPKVLRHFTARLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: TSAD_ORITI
Sequence: MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATSGPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDAVGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQYTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYCGVAPPSNLCTDNAAMIAWAGIERLNANLFSSNFVPRAKWSVEEL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_ESCF3
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLTMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALIKVPENWIVQGDFEPESGYRAMQQILAQTHRPTAVFCGGDIMAMGALCAADEMGLRVPQDISVIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: AMPA_BURM1
Sequence: MDFSIKGCDWSKGEAKGFLTGKSDCIVLGIFEAQTLSGAALDIDTATKGLISRVVKAGDMDGKRGKTLFLPEVSGIGASRVLLVGLGKQDAFNQKAYNDAVTAAWRALLATKVVQVTFTLAQLPVDERGSDWGVRAAILALRNETYRFTQMKSKPEPVSHTLKRVVFSVEPADEKAAKVAVKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKQLAKDWGMKAEVLGLKQIQALKMGSFLSVARASVEPPQFIVLHYQGAAAKAAPIVLVGKGITFDTGGISLKPGEGMDEMKYDMCGAGSVLGTIRAVAEMGLKLNVVGIIPTCENMPGGNATKPGDVVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDIATLTGACIIALGHHNSGLFSKDDALAGELLDASREANDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFTENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_OLTVI
Sequence: MKNIKNSPKLQLKSTGTPFQGTVDYKNIALLRKYISTEGKILPRRITGLTAKQQRAVAKAIKNARMVGLLPFINLEGY
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GSA_PSESM
Sequence: MSRSETLFANAQKHIPGGVNSPVRAFKSVGGTPLFFKHAAGAYVTDEDDKRYVDYVGSWGPMILGHSHPDVLDAVRNQLEHGLSYGAPTAMETEMADLVCELVPSMEMVRMVSSGTEATMSAIRLARGFTGRDSIIKFEGCYHGHSDSLLVKAGSGALTLGVPSSPGVPAAFAKHTLTVPFNDLNAVRDLLAEVGQEVACIIVEPVAGNMNCVPPAPGYLQGLRALCDEHGVVLIFDEVMTGFRVALGGAQAYYDVKPDLSTFGKIIGGGMPVGCFGGKREIMSHIAPLGPVYQAGTLSGNPLAMAAGLTTLRLISRPGFHDELSDYTRRLLEGLQQRADAAGIAFVTTQAGGMFGLYFSDASEIVTFEDVMTSDAERFKRFFHLMLEGGVYLAPSAFEAGFTSIAHGDAELKLTLDAAEKAFAALK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_PSEAB
Sequence: MRLIRTLFVAALAMGASLAHADDSAAVQRLTGLLNKAQTLTARFSQLTLDGSGTRLQETAGQLSLKRPGLFRWHTDAPNEQLLISNGEKVWLYDPDLEQVTIQKLDQRLTQTPALLLSGDISKISESFAITYKEGGNVVDFVLKPKTKDTLFDTLRLSFRSGKVNDMQMIDGVGQRTNILFFDVKMNEALDAKQFTFDVPPGVDVIQE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DNAJ2_STRAW
Sequence: MATDYYAVLGVRRDASQDEIKKAFRRLARELHPDVNPDPKTQERFKEINAAYEVLSDPQKKQVYDLGGDPLSQSGGGGAGGFGAGGFGNFSDIMDAFFGTASQRGPRSRTRRGQDAMIRVEIELDEAAFGTTKDIQVETAVVCTTCSGEGAAPGTSAQTCDMCRGRGEVSQVTRSFLGQVMTSRPCPQCQGFGTVVPTPCPECAGDGRVRSRRTLTVKIPAGVDNGTRIQLAGEGEVGPGGGPAGDLYVEIHELPHQTFQRRGDDLHCTVTIPMTAAALGTKVPLETLDGMEEVDIRPGTQSGQSIPLHGRGITHLRGGGRGDLIVHVEVTTPTKMDPEQERLLRELAKLRGEERPTGQFQPGQQGLFSRLKDAFNGR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_YERPP
Sequence: MMTQDYKLQVEAIKCGTVIDHIPAQIGFKLLSLFKLTATDQRITIGLNLPSKRSGRKDLIKIENTFLTEQQANQLAMYAPDATVNRIDNYEVVKKLTLSLPERIDAVLTCPNSNCISHNEPVDSSFTVKAQRGEISLKCKYCEKEFDHLTVLHAD
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: TOM22_MOUSE
Sequence: MAAAVAAAGAGEPLSPEELLPKAEAEKAEEELEEDDDDELDETLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKM
What is the function of this protein?
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM22 homolog, Translocase of outer membrane 22 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom22 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PPNP_ECOLU
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TRMB_VIBVU
Sequence: MSEVTTNEYNEDGKLIRKIRSFVRREGRLTKGQENAMKECWPTMGIDYQKQLLDWKEVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFFGIEVHSPGVGACLSDAREAGISNLRVMCHDAVEVFEHMIPNDSLATLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLIPNEGIFHMATDWENYAEHMIEIMNQAPGYRNIAEAGDYIPRPEERPLTKFEARGHRLGHGVWDIKFKRVS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ATPG_XANOM
Sequence: MAGGREIKTKIKSVQNTRKVTRALEMVSASKIRKAQERMKTSRPYAQAMKQVIGHLAQASTDFQHPFLIEREQVKRVGYIVISSDRGLAGGLNNNLFRKMLGEVRPWQGTGAEIDVVTIGQKASAFFRRIKVNMVGSVTHLGDSPQVEQLIGVIKVMIDAFIEGKVDRVYLVYNRFVNTMTQKASFDQLLPLPAAEHKVAHHDWDYLYEPDAASVLEHVMTRYIESLVYQAVLENVASEHAARMVAMKAASDNANKMIGTLQLVYNKARQAAITQEISEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURD_RUEPO
Sequence: MIPVKGFAGANVAVLGLGRSGLATARALRAGGAEALCWDDNPAAREAAEGEGFTIRDLRKQGVRDDTACLIVSPGIPHLYPAPNPVVAAALEAGVPVDNDIGLFFRSFAGPEWDGFDTLPRVVAVTGSNGKSTTSALIHHILSEAGRPVQLAGNIGRGVLDIEPGEEGSVVVLELSSYQTDLARALTPDVAVFTNLSPDHLDRHGGMGGYFAAKRRLFAEGGPDRAVIGVDESEGLYLAGQMSEGPGDDRVIRVSVSRKLTGPGWQVFARKGYLSEYRKGRQAGSIDLRDIRGLPGAHNHQNACAAYAACRALGLSPKAIEAGMRSYPGLPHRSQIVAEAGGVTYVNDSKATNVDAALKALGAFKRIRWICGGLQKEGGIAALNGGLAEVLKAYVIGREAAGFALQLEVESEVCTTMDEAVARAMAEAEPGDTVLLAPAAASFDQYDNFERRGEDFMAEVQKRLDG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DING_MYCBO
Sequence: MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTATIALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAWASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEHRLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSALRDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELLATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIAELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLIDRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFWQTTNATQVRAALRRLARADAKAH
What is the function of this protein?
Probable helicase involved in DNA repair and perhaps also replication.
What are the official names of this protein?
Probable ATP-dependent helicase DinG homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily.
Protein: RL3_CALS8
Sequence: MTKGILGKKIGMTQVFDEAGKVVPVTVIEAGPCVVVQKKTVEKDGYAAIQVGFEDIKETKLNKPLRGHFAKHGVKPKRYLRELRLKDADKYEVGQEIRVDIFSPGERVDVTGISKAKGFQGVIKRHGQQRGPMSHGSMYHRRVGSMGSNTFPARTFPGKKMPGRMGGQRVTVLNLQVVKVDPERNLLLVKGSVPGNKNSLLIIRDSVKSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: FOLC_ECOLI
Sequence: MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSLVAARLGVLKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSGGK
What is the function of this protein?
Functions in two distinct reactions of the de novo folate biosynthetic pathway.  Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu).  Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
What are the official names of this protein?
Dihydrofolate synthase/folylpolyglutamate synthase, DHFS / FPGS, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, Folylpolyglutamate synthetase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: PSBN_SYNJB
Sequence: MEPTFSLIVAIAAVTICITAFAIYTAFGPPSKDLQDPYEMHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: FETP_CROS8
Sequence: MSRTIFCTFLQRDAEGQDFQLYPGELGKRIYNEISKEAWAQWQKKQTMLINEKKLNMMNPEHRKLLEEEMVNFLFEGKEVHIEGYTPPEQQ
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NCAP_ABLVB
Sequence: MESDKIAFKINNQLVSVKPEVIVDQYEYKYPAIKDQRKPSITLGKAPDLNKAYKSILSGMNAAKLDPDDVCSYLAAAMELFEGICPEDWTSYGILIARKGDKITPATLVDIRRTDIQGSWALAGGQDFTRDPTIAEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFAKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRVEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQIRSLNATVISTCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQDYEAAEAMKIDLALADDGTVNSYDEDYLSGETRSPEAVYTRIMMNGGRLKKSHIRRYISVSSNHQSRPNSFAEFLNKTYSSDS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: SGT1_RAT
Sequence: MAAAAAGPASSQRFFQSFPDALIDGDPQAALEELTKALEQNPDDAQYYCQRAYCHILLGKYCDGIADVKKSLELNPNNSTALLRKGICEYYEKDYASALETFAEGQKLDGTDTNFDIWIKRCQEIQNGSEPEVSASQRTQSKIKYDWYQTESHVIITLMIKNVQKNDVRVDFSEKELSAVVKIPSGEDCSLKLRLLHPIIPEQSTFKVLSTKIEIKMKKPEAVRWEKLEGQGDVPAPKQFTADVKNMYPSSSHYTRNWDKLVGEIKEEEKNEKLEGDAALNKLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKQY
What is the function of this protein?
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Protein SGT1 homolog, Suppressor of G2 allele of SKP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates the to nucleus upon heat shock, requiring S100A6.
Protein: PURA_LACPL
Sequence: MASVVVVGSQWGDEGKGKITDFLSQEADVVSRYQGGDNAGHTIVFNGQTFKLRLIPSGIFFHDKLAVIGNGVVLNPKSLVEELQYLRDKGVNPDNLRISNRAHVILPYHITLDGAQEKAKAGGKIGTTNKGIGPAYMDKAERIGIRVADLLDKDTFAALLKRNLAEKNQIITKLYDLEPLKFEDIFDDYYAYGQTLKPFVTDTSVVINDALDNGQRVLFEGAQGVMLDIDQGTYPYVTSSNPVAGGVTIGSGVGPSKIDNCVGVLKAYTSRVGDGPFPTELFDEVGDFIRETAHEYGTVTKRPRRIGWFDSVVLRHAKRVSGFTHLSLNCLDVLTGLKTIKVCTAYDLNGETIYHYPASLKELEACKPIYEELPGWDEDITGVKTFEELPTNAQNYLRKLEELVGVKIATFSVGPDREQTNVIDHNIWG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_PHOV8
Sequence: MSKETLKANLREIPDFPIPGILFYDVTTLFKNPECLQEILDTLYEMYKDKGITKVVGIESRGFIMGGALAARLGAGFVMARKPGKLPAEVVEETYAKEYGTDTIQIHKDAIDENDVVLLHDDLLATGGTMAATHRLVQRCGAKKIFINFIIELGGLNGRKAFPEDITVDTLLTL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SHEFN
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFESAGLKIIASKMVQLSKEQAEGFYAEHSARPFFGALVSFMTSGPVMVQVLEGENAVLANREIMGATNPAEAARGTLRADYAASIDENAVHGSDAVESAAREIAYFFSADEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.