PharMolix/UniProtQA huggingface dataset:
Protein: NAT8L_RAT
Sequence: MHCGPPDMVCETKIVATEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKGIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE
What is the function of this protein?
Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA (PubMed:18621030).  Promotes dopamine uptake by regulating TNF-alpha expression (By similarity).  Attenuates methamphetamine-induced inhibition of dopamine uptake (By similarity).
What are the official names of this protein?
N-acetylaspartate synthetase, NAA synthetase, N-acetyltransferase 8-like protein.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Cytoplasm. Microsome membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PCYA_THEVB
Sequence: MSLRQHQHPLIQRLADRIEAIWQAFFPLAPYALPEDLGYVEGKLEGERLTIENHCYQAPPFRKLHLELARVGESLDILHCVMFPEPRYDLPMFGCDLVGGRGQISAAIVDLSPVTGQLPAAYTCALNALPKLTFRQPRELPPWGHIFSPFCIFIRPQGEAEEQQFLDRIGEYLTLHCQLSQQAVPTDHPQAVIAGQRQYCQQQQQNDKTRRVLEKAFGVPWAERYMTTVLFDVPPV
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: ASSY_SHELP
Sequence: MSIENNKASVKKVVLAYSGGLDTSAIIPWLKETYDNCEIVAFCADVGQGEAELEGLHEKAIASGASECYIVDLKEELVADYIYPTIATGAIYEGTYLLGTSMARPIIAKAQVEVARKVGADAVCHGCTGKGNDQVRFEGCFAALAPDLTVIAPWREWSMVSREDLLDYLAERNIKTTASATKIYSRDANAWHISHEGGELEDPWNEPSKEVWTMTVAPEDAPDEPEYVSVEMEAGRITKVNGQSYTPYGALMALNEIAGAHGVGRIDITENRLVGMKSRGCYETPGGTVMFAALRAIEELVLDKTSREWREQVGAKMAHLVYDGRWFTPLCESLLGASQPLANLLNGEVVLKLYKGQAQAVKKRSPNSLYSEEFATFGEDEVYNQKDAEGFIRLYSLASRIRALNVK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y676_METJA
Sequence: MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIGITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAEIIGYATKEHKGVIIETIVGRRIVDMPIGDPIPRVC
What are the official names of this protein?
Putative hydrogenase expression/formation protein MJ0676.
What is the protein family that this protein belongs to?
Belongs to the HypE family.
Protein: THOC6_RAT
Sequence: MEHATPLAVPLGQAEVFQALQRLHMTIFSQSVSPCGKFLAAGNNYGQIAIFSLSAALSSEAKEESKKPMVTFHAHDGPVYSMVSTDRHLLSAGDGEVKGWLWAEILKKGCKELWRRQPPYRTSLEVPEINALLLVPKENSLILAGGDCQLHTMDLETGTFTRALRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRIAKEVQTIEVYKHEECSRPHNGRWIGCLATDSDWMVCGGGPALTLWHLRSSTPTTVFPIRAPQKHVTFYQDLILSAGQGCCVNHWQLSGELKAQVPGSSPGLLSLSLNQQPAAPECKVLTASGNSCRVDVFTNLGYRAFSLSF
What is the function of this protein?
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.  Plays a role in apoptosis negative control involved in brain development (By similarity).
What are the official names of this protein?
THO complex subunit 6 homolog, WD repeat-containing protein 58.
What is the protein family that this protein belongs to?
Belongs to the WD repeat THOC6 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: RL5_CHLTB
Sequence: MSRLKKLYTEEIRKTLQDKFQYENVMQIPVLKKIVISMGLAEAAKDKNLFQAHLEELAVISGQKPLVTRAKNSIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSCKGDGRGCYSLGLDDQQIFPEVDLDRVKRSQGMNITWVTTAQTDAECLTLLECMGLRFKKAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: HSLV_CALBD
Sequence: MFHATTIVAVKKGESVAIAGDGQVTFSQNMIMKSTAKKVRKLYNGKVLVGFAGSVADAITLCEKFEEKLEQNSGNLQKSVVELAKEWRQDKVLRRLEALMVVADKDHLFVVSGSGEVVEPDDNIAAIGSGGPYALAAARALLQSTDLSAAEIARKALEIAASICVYTNNNITVLEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_BRUA4
Sequence: MTDQRPSLEIRLCGPRGFCAGVDRAIQIVVLALKKYGAPVYVRHEIVHNRYVVEGLQSRGAIFVEELHEIPAEHRDQPVVFSAHGVPKSVPADAEAKNLFYLDATCPLVSKVHKQAMRHQRLGRHVILIGHSGHPEVIGTMGQLPDGAVTLIETVEDARSCHFDDENNLGFVTQTTLSVDDTAGIIEELQARFPNLSAPAAESICYATTNRQDAVRSAAPGCDLFLIVGAPNSSNSKRLVEVAEKAGARMSMLVQRAADIEWDRIGDISVVGLSAGASAPEIIVDEIIDAFKARFNVKIELAETTVETENFLVNREIRDVELTVQDMAFVNGEHRVVGIPKLMPKIIQGK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NUSB_MYXXD
Sequence: MGARRTGRERALQALYQLEMATATTAEALESAWSAAEESNKRDPDAVKFARELVEGVQSHRDEIDQLIERHSHNWRLDRMSRIDRNVLRLGIFELKYRPDIPRKVSINEAVELGKNFGNEESSAFVNGLLDRVAVALNKP
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: LDH_LACLM
Sequence: MKITSRKVVVIGTGFVGTSIAYSMINQGLVNELVLIDVNQDKAEGEALDLLDGISWAQENVIVRAGNYKDCENADIVVITAGVNQKPGQSRLDLVNTNAKIMRSIVTQVMDSGFDGIFVIASNPVDILTYVAWETSGLDQSRIVGTGTTLDTTRFRKELATKLEIDPRSVHGYIIGEHGDSEVAVWSHTTIGGKPILEFIVKNKKIGLEDLSNLSNKVKNAAYEIIDKKQATYYGIGMSTARIVKAILNNEQVILPVSAYLRGEYGQEGVFTGVPSVVNQNGVREIIELNIDAYEMKQFEKSVSQLKEVIESIK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRR1_HUMAN
Sequence: MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.  Rho-1 GABA receptor could play a role in retinal neurotransmission.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit rho-1, GABA(A) receptor subunit rho-1, GABA(C) receptor.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: AMP1_MELGA
Sequence: MRIVYLLFPFILLLAQGAAGSSLALGKREKCLRRNGFCAFLKCPTLSVISGTCSRFQVCCKTLLG
What is the function of this protein?
Bactericidal activity; inhibits S. aureus and E. coli.
What are the official names of this protein?
Antimicrobial peptide THP1, Turkey heterophil peptide 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_CHLMU
Sequence: MSNVLPKGVFDIFPYVTNSKNLWRNSFLWKTVEHAAHRICNLYGFDEIRTPVFEKTETFLRVGEHSDIVKKEVYTFLDKKGRSLTLRPEGTAAVVRALLDHSADMRKDNKIYYILPMFRYERQQSGRYRQHHQFGLEAIGVRHPLRDAEVLSLLWDFYAAVGLKHMQIQVNFLGGRKTRARYDEALREFFRKDLDKLSTLSQERFHANLLRILDSKEPEDQAFIEQAPSILDYVDDQDLNYFDSVLAELKVLGIPYKINPRLVRGLDYYTDLVFEAVTVVGDHSYALGGGGRYDELVAQSGGPAMPAFGFGVGLERVIQTLLEQGAALPTAPRRLRLIPMDESADAFCFSWAKHLRHLGVATEVDWAHKKPKTALKDAADQQVGFVCFVGEQELSTKQFIVKDMSLHQSFSGAQQDVEQRLVYEVQNA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_CAMJE
Sequence: MKHIEIYTDGSCLNNPGFGGWAYILRYKEYQKEGFGAEANTTNNRMELMAIIESLKALKEPCEISLFTDSNLMVQSINEWLEGWIKKDFKGKKNIDLWKEYIKVAKSHKIKAFWVKAHNGHLENERCDTLAREAALKIARENDEKH
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HI, RNase HI.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR55_DROER
Sequence: MHTHNNFKTPSDEDELDDLDEDMVVGVIAEIEQEVLNESDSDNDEYDLVEMGAPVPDNDGDSSYDGNESISSDDSFDPNAADSDSDDSMLDDAGDDASAGGATSSKRRKDDDNPSGSNRQSEATFDLDEDDETDETVRAMIAAIKKPRSAPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEANKLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAINTLHVLNENLFATGDDAGTVKLWDLRTKNAIFELKELEDQITQLTTNDQSKLLLATSADGYLTTFNIAARKMYVQSEPYEEELSCMGIYRGDSKLVVGTSKGRLYTYNWGQFGYHCDMYPGIKSPISLMIPITDRIACVAGEDGNIRACHIAPYRNLGVVGQHNMPIESLDVNSNGELIASSSHNNDVRFWNVKYFEDFGDIKYNEKHNAYKEQRHNLPSSKCSNASDFFADLTKEDADDDDAGAGPSNMA
What are the official names of this protein?
WD repeat-containing protein 55 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
Protein: QUEF_KLEP7
Sequence: MSSYDNHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGLHADNLPFHGADIWTLYELSWLNGKGLPQVAVGHVELPDTSLNLVESKSFKLYLNSFNQTRFASWQDVAETLTRDLSACAQGKVKVSLYRLDELEGQPIARLHGTCIDDQDIEIDNYQFSADYLQGAASGKIVEETLVSHLLKSNCLITHQPDWGSVQIQYRGAKIDREQLLRYLVSFRHHNEFHEQCVERIFNDILRFCQPESLSVYARYTRRGGLDINPWRSNGDFSPATGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORR_ENT38
Sequence: MSFSVEVLARIAIELQTGIGHQDRFQRLISTLRHVLDCDASALLRYEGRQFIPLAIDGLAHDVLGRRFTLEGHPRLETIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACIGLPLFAGQNLIGALTLDGLEPDQFDTFSDEELRLIAALASGALNNALLIEQLESQNIMPGSPVAFEHVAHTEMIGLSPGMMQLKKEIEIVAASDLNVLIGGETGTGKELVAKSIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGNFRADLFHRLSVFPLSVPPLRERGEDVVLLAGFFCEQCRLKMGLSRVVLSPGARSHLLSYGWPGNVRELEHAIHRAVVLARAARLGDDVVIHARHFALHDEAAPAVAQELPAIANENLREATEAFQRQMITRALDQNGRSWAACARALEMDVANLHRLAKRLGLKG
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: ATPA_PROMP
Sequence: MVSIRPDEISSILKQQITDYDQSVNVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMKGRVVNPLGQPIDGKGEIPTSDNRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALEYTVVVSAGASEAAALQYLAPYTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDDMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLRELLKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEKKLNEGLETTLKEVIKEVKSSMLATV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: AKAP1_CAEEL
Sequence: MVAAAAADALAAGGDSSSPSDLYNKITGQQSSTTTSLSYAACDVITRHLISMLLEISNWTNDLAKYLAGSEQSSDDGHNERCLLFSSIFFAIDPSLALAQMSSVASKHALLIALGGFSIAALFVWYINKKDKDGRKKKKVGDVISNGLPKTATASDVQTENGNVKKANGHVNGDVQSSIGVSQKQQQKDEDEKTQKKDAVQNEKPSIDKKQPKSQAPTEKKEEKTVEIHTETEETDHVAAGDSGVVSEHKEHDKKTKQKNDEPVSIDKKSEEIEVPKQAGVVNEEPKKQSEETVVEEQFVKKEEPKLKSAPTPLLTMPSKKKVLENEQIPEEPTPTKMNDATSPLSLDIAAQMSPASFSWSEEMEKSFNEEEFRLNESSDIDRSPASPLRHLQQQHNKNRSSQKRKGGRVNGRDGVHQPQQQHQQQKKEEQGQIKKGQRRLTKEKSVEETPEKSQKRVVLKHHENEAGDAAHAQIIESPHHENASYEKSDSPGLDSQNSEASSQDSGRATGPLASPHEDGLTTEDDFLPMYEFEIPNSLVGLIIGVKGKTIKELSVRTNVRMLIRQHHETDKVKTHQICQVRGKRDEINHCLQMLRRRFPPARFPELNLQPVVPPVLPNSNFDMLSTQPTWLTLPEDIKCEVAVSSIISASHFFIQQPTHPSFASLRHLDMYMGSLYGEQSNLPELPIPCQNGLLCAAPVGNAWFRAVTVQYFDETDEVFVKFVDYGGYSKMARQDLRQIRTDLMSLPFQSTEVMLAHVRPVDGTTNWSDAAMQKFRAMCIGKVINCKMVGQSHDTRIPMVELYMMSKDGKDAQEVRFDQVLMNCGLARTADPSKMSRITVPAALDTESRMKRPSFSSQTSQTAVVC
What are the official names of this protein?
KH domain-containing protein akap-1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THTM_ECO57
Sequence: MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPLK
What is the function of this protein?
Catalyzes the transfer of sulfur from 3-mercaptopyruvate to a thiol-containing acceptor to form an intramolecular disulfide releasing hydrogen sulfide and pyruvate.
What are the official names of this protein?
3-mercaptopyruvate sulfurtransferase, MST, Rhodanese-like protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR4F_ARATH
Sequence: MRRSRFVAQVFSDVTFADASTISAPIFTMSTRAPYRGARGRGRGRGGRSFSDRPYNDDAGRDQFVTGDSHFQSVHDANFRFRHGEPYRQHQPPLDQRQQPPFNQNYEFRPPPPSRGQWQQFRQPNQFPSNQNYAACPPPPFYQNQMSRPPPQQSFRQRPRSKPSDYREWEYAKTPPSPGSEKFVVLSYNILADYLANDHWRSLYFHIPRNMLSWGWRKSKLVFELSLWSADIMCLQEVDKFQDLEEEMKHRGYSAIWKMRTGNAVDGCAIFWRSNRFKLVHEESIQFNQLGLRDNVAQICVLETLLTSHTKENETPPPESSAGSHRVVICNIHVLFNPKRGDFKLGQVRTLLDKAHAVSKLWDDAPIVLCGDFNCTPKSPLYNFISDRKLDLSGLARDKVSGQVSAEFRPPRPENYTTRYQSANKSPQGQVQPPNLITNAHMENNSNIDVGTAPSEKTSELPCGDTILAGHEATSSSDQVLPCENMASDCQFGIENRKPDDSGNLSTAEDLSSLTISDTEPQHASSAREDLNTDRSVSSGLSETEQTPEEICSSDQDISSSLSTKVDTFVAEMKLDGLKLDEPVVFAQDEESLGEDGETFLAKLHDNNENLSQKGELVSEVPLKWSSEALNSDKITYSPSSWTPMEIATATGDPERTTVEHALELKSTYSEVEGQANTRDENGEPVVTSYHRCFMGTVDYIWRSEGLQTVRVLAPIPKQAMQWTPGFPTPKWGSDHIALVSELAFCSSKTLPKS
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.
What are the official names of this protein?
Carbon catabolite repressor protein 4 homolog 6, CCR4 homolog 6.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DADA_ECOL5
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: PURT_GEOMG
Sequence: MIGTPLKKSATRVMLLGSGELGKEVVLEAQRLGVEVIAVDRYADAPAMQVAHRAHVVNMLDRVELGRIVARERPHLIVPEIEAIDTPYLLELEQEGYTVIPTARAANLTMNREGIRRLAAEELGLPTAAYRFAASIESFRAAVKDIGLPCVVKPIMSSSGKGQSVVKSMEEIDGAWTYAMEGGRGASDTVIVEEFIPFDYEITLLTVRHAGGTTFCPPIGHVQIKGDYHESWQPMAMTPAALAESQRQAKAVTDALGGSGIFGVELFIKGDRVWFSEVSPRPHDTGMVTMISQNLSEFELHVRAILGLPVPEVANLAPAASHVVLASEAAEEVTFSGLDAALSVPETKLRLFGKPDTRPGRRMGVALSFGADTDEARNRAEQAAHAVKIVTL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL10_UREU1
Sequence: MANVRPSVVFKQQEVDHMADILKNSKSFIVFEYHGLTAANILALRNVLHSSNSKLFVLKNNITARAFEKAGVTGFEDRLTGPNAIAVAMDDEIAAIKAVNDVAKEFDFVKIKGAYLENKFADTHKIDQLAAIPGREGLYSMLLSCFTAPLRNVLYGLKAVAEQKGE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RR2_PANGI
Sequence: MTKRYWNINLEEMMKAGVHFGHGTKKWNPKMAPYISAKRKGIHITNLTRTARFLLEACDLVFDAASRGKQFLIVGTKNKAANLVAWAAIKARCHYVNKKWLGGMLTNWSTTETRLHKFRDLRTEQKTGRLNRLPKRDAAMLKRQLSHLQTYLGGIKYMTGLPDIVIIVDQHEEYTALRECITLGIPTICLIDTNCDPDLADISIPANDDAISSIRLILNKLVFAICEGRSSYIRNP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUDL_SALCH
Sequence: MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQPGLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNSHRVWLSWYEHYFVWGMTANILRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: BTUD_SHIFL
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MINE_PSEPW
Sequence: MNLFDFFRGRQKQTSASVAKERLQIIVAHERGQRSEPDYLPALQKELLEVIRKYVNIGSDDVHIELENQGSCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SRY_HALGR
Sequence: MFGVLNSNDHRAAVQQRNIPAFGRTSFEPWTDNPTSNYRCETGGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKALPQKSDKLLPAASSSMLCRQVLVDEKWYPFTYRDSCSRAAHSRMEDQLSSSQPVNIANSLLQQEHHYRSTSLGDSPETLAAHLSADPPFYPKEQLGLSDAYFP
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.