PharMolix/UniProtQA huggingface dataset:
Protein: EFG_SHISS
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_NEIMB
Sequence: MQIILLEKIGGLGNLGDIVTVKNGYARNFLIPAGKAKRATEANMKEFEARRAELEAKQAEILADARVRQEKLDGQTVTVAQKAGVDGRLFGSVTNADIAAAIVAAGIEAVKANVRLPNGPLKAVGEYEVEVALHTDAVAKITVAVVAATE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CLP1_CHAGB
Sequence: MSIPGLGQIAPQQPTTSTTRTITLRPFWEWRFEVPRSSIPTTNAAISAIGLGGAGAGGGGATVRLTSGTAERDGTELALNRTYTFPRNTQSKLLTYTGATLEVSGAFVDSVAQYPAPEASPQLPVLNLHFALQELRAAAAAGGSNHNNNNTNGGGAPGPRVMICGEKDSGKTTVARTLAALATRAGGQPLVGSVDPREGMLALPGTVSAAVFGTVMDVEDPAAGFGVSGTPSSGPSAVPVKLPMVYYVGRERVDEDVPLWRDLVGKLGSAVRDKFAADEVVREAGLLLDTPAASVAKGDLEVLTHVVNEFAGGLLGAGRTAGWQLTVTVNIVVVLGSVDLHAELQRRFENQRTVHGEAITLILLDKSDGVAERDKDFMKFTREAAIKEYFFGDAKRTLSPFTQSVSFDDVAVFRTPDALERAEVSAEMSHWTLAVMNASVNDPPEVIRQAPVMGFVAIADVDEDRRRLKVLSPVSGRLGNRPMIWGRWPEPYINLLG
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAMT_ARATH
Sequence: MSTSFTMIGGEGPNSYREHSKYQGALVIAAKEKINEAISTKLDIDFTSNLVNIADFGCSSGPNTFTAVQTLIDAVENKYKKESNIEGIEFQVFFNDSSNNDFNTLFKTLPPARLYFASGVPGSFFGRVLPKNSLHVGVSSYSLHFVSKVPKEIKDRDSLVWNKDIHCSGSSKEVVKLYLGQYKIDVGSFLTARAQELVSGGLLLLLGSCRPTGVQMFETVEGMMIDFIGSSLNEIANQGLIDQQKLDTFKLPIYAPNVDELKQIIEDNKCFTIEAFEKISHAKGEYPLDPEYLTSAFKVTVGGSVASLFGQDGMEKTYELVKEKTQEMLPQIAKAKPGMQYLIVLRRN
What is the function of this protein?
May catalyze the production of the insect juvenile hormone methyl farnesoate (MeFA) to trigger defense against insect herbivory.
What are the official names of this protein?
Farnesoic acid carboxyl-O-methyltransferase, SABATH methyltransferase FAMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. SABATH family.
Protein: BH127_ARATH
Sequence: MMIISSQILLLFGFKLFFETRGEDDIVELLCKIGQTQIPSSDPLPILRGSGSGGREENTPLPPPLPHQNLFIQEDEMSSWPHHPLRQDYLCSELYASTPAPHPQSSVSLAPPPPKPPSSAPYGQIIAPRSAPRIQGTEEARGSTSRKRSRAAEMHNLAERRRREKINERMKTLQQLIPRCNKSTKVSMLEDVIEYVKSLEMQINQFMPHMAMGMNQPPAYIPFPSQAHMAGVGPSYPPPRYPFPNIQTFDPSRVWLQSPQPNPVSNQPQMNPYGQFVGHHQMQQSLPPPLQVILSQYPLCLFLCSNK
What are the official names of this protein?
Transcription factor bHLH127, Basic helix-loop-helix protein 127, AtbHLH127, bHLH 127, bHLH transcription factor bHLH127.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPU_HV1BN
Sequence: MQPLQISAIVALVVAAIIAIVVWSIALLEYRKLLRQRKIDRLIDRIRERAEDSGNESEGDQEELSALVEMGGHDAPWDIDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: MAMO_MAGGM
Sequence: MIEIGETMGDQPTNKIVFCERSWKAPVSILAFLILVTFAWGAYLLDNYDEDDYFRGSDDMSVGQFLVRNVAMPDVQRLYYTVPPAVVGVGGGGVNAGPVASGAIVGANGYVITTLHSVANVPDITVQVATSAGIRRFPAQVVKTIPGHNLALLKLQTTEKFLHFRMANIQTVVPGQQVFAFGRNMAGAPLVRQGMVQSSDAPLAVGTTQITHLLRSDAVYSWEQTGGPLVNAQGDLVGINIAATGPTGKVEGFTVPAQVIVSHLQDVVRFKTGGAAGVAPPAAQTVAMGSSSWWSKAKAVVGGPTAVPGMGMNVVQGTVTTGIPSGMPFVDTDHVGGAKIGGYSIADILGLGMLALAAGVTGGMMTMGGGVLQVAGMMVFFGYGMYLIRPVVFLTNVVVYGAAALRNDKAQLVQWDKVKPLIPWGVAGVVIGYFIGNAIGDSVVGVLLGLFALIMAGKAVLEILQPNAGEDTAEAIAAAEAGDEMDELMALAEGTTRPKTSGIALPEGPTRSAVLGLPMGLFSGILGISGGVIEVPLQRYIGRISLQNAIANSSVLVFWASVAGSVVAFIHGGSTGLIHWEAPVTLALVMIPGAYVGGILGARLMRVLPVRVLKGIYAATMAAIAIKMLTTV
What is the function of this protein?
Plays 2 roles; promotes magnetite nucleation/formation and activates the MamE protease (By similarity) (PubMed:20674739).  Despite its near conservation of a protease-like sequence, this is probably not a protease (By similarity).  Required in conjunction with MamP for proteolysis of at least MamE, itself and MamP (By similarity).  May transport a solute that controls MamE's protease activity.  May place individual iron atoms into the magnetite lattice (By similarity).  One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis (PubMed:27286560).
What are the official names of this protein?
Probable membrane transporter protein MamO.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein.
Protein: RLMH_SHIDS
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFQ8_SCHPO
Sequence: MDFTTNEVLFSRLVVCKNLTRKNFPFLQLKGSSILRFEWSEEMYRLYIWLLPYRKDYNEKFKGILINPSIFLLGCHHVQICSFPNNLVFFMGKCDLFRFC
What are the official names of this protein?
Putative uncharacterized protein C8E11.08c.
Protein: SLAP1_ACET2
Sequence: MKRKNKVLSILLTLLLIISTTSVNMSFAEATPSIEMVLDKTEVHVGDVITATIKVNNIRKLAGYQLNIKFDPEVLQPVDPATGEEFTDKSMPVNRVLLTNSKYGPTPVAGNDIKSGIINFATGYNNLTAYKSSGIDEHTGIIGEIGFKVLKKQNTSIRFEDTLSMPGAISGTSLFDWDAETITGYEVIQPDLIVVEAEPLKDASVALELDKTKVKVGDIITATIKIENMKNFAGYQLNIKYDPTMLEAIELETGSAIAKRTWPVTGGTVLQSDNYGKTTAVANDVGAGIINFAEAYSNLTKYRETGVAEETGIIGKIGFRVLKAGSTAIRFEDTTAMPGAIEGTYMFDWYGENIKGYSVVQPGEIVVEGEEPGEEPTEEPVPTETSVDPTPTVTEEPVPSELPDSYVIMELDKTKVKVGDIITATIKIENMKNFAGYQLNIKYDPTMLEAIELETGSAIAKRTWPVTGGTVLQSDNYGKTTAVANDVGAGIINFAEAYSNLTKYRETGVAEETGIIGKIGFRVLKAGSTAIRFEDTTAMPGAIEGTYMFDWYGENIKGYSVVQPGEIVVEGEEPGEEPTEEPVPTETSVDPTPTVTEEPVPSELPDSYVIMELDKTKVKVGDIITATIKIENMKNFAGYQLNIKYDPTMLEAIELETGSAIAKRTWPVTGGTVLQSDNYGKTTAVANDVGAGIINFAEAYSNLTKYRETGVAEETGIIGKIGFRVLKAGSTAIRFEDTTAMPGAIEGTYMFDWYGENIKGYSVVQPGEIVAEGEEPGEEPTEEPVPTETSADPTPTVTEEPVPSELPDSYVIMELDKTKVKVGDIITATIKIENMKNFAGYQLNIKYDPTMLEAIELETGSAIAKRTWPVTGGTVLQSDNYGKTTAVANDVGAGIINFAEAYSNLTKYRETGVAEETGIIGKIGFRVLKAGSTAIRFEDTTAMPGAIEGTYMFDWYGENIKGYSVVQPGEIVAEGEEPGEEPTEEPVPTETPVDPTPTVTEEPVPSELPDSYVIMELDKTKVKVGDIITATIKIENMKNFAGYQLNIKYDPTMLEAIELETGSAIAKRTWPVTGGTVLQSDNYGKTTAVANDVGAGIINFAEAYSNLTKYRETGVAEETGIIGKIGFRVLKAGSTAIRFEDTTAMPGAIEGTYMFDWYGENIKGYSVVQPGEIVAEGEEPTEEPVPTETPVDPTPTVTEEPVPSELPDSYVIMELDKTKVKEGDVIIATIRVNNIKNLAGYQIGIKYDPKVLEAFNIETGDPIDEGTWPAVGGTILKNRDYLPTGVAINNVSKGILNFAAYYVYFDDYREEGKSEDTGIIGNIGFRVLKAEDTTIRFEELESMPGSIDGTYMLDWYLNRISGYVVIQPAPIKAASDEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPTPTTTPTPTPSTTPTSGSGGSGGSGGGGGGGGGTVPTSPTPTPTSKPTSTPAPTEIEEPTPSDVPGAIGGEHRAYLRGYPDGSFRPERNITRAEAAVIFAKLLGADESYGAQSASPYSDLADTHWAAWAIKFATSQGLFKGYPDGTFKPDQNITRAEFATVVLHFLTKVKGQEIMSKLATIDISNPKFDDCVGHWAQEFIEKLTSLGYISGYPDGTFKPQNYIKRSESVALINRALERGPLNGAPKLFPDVNESYWAFGDIMDGALDHSYIIEDEKEKFVKLLED
What are the official names of this protein?
Cell surface glycoprotein 1, Outer layer protein B, S-layer protein 1.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: RSMG_HAEDU
Sequence: MKQKLDRLLVQADIQLTERQKEQLIGFVHLLHKWNKAYNLTSVRDPEEMLVKHIMDSLVVSVHLQGQSFIDVGTGPGLPGIPLAIANPDKQFVLLDSLGKRITFIKQVLRELAITNVTPVLSRVEQYTARQFDGVLSRAFASLDDMLNWCYALPNDSGKFYALKGVYDGTELQAVQKPIKLVDAIKLNVPQLVGERHLIVLAK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR4_SARBU
Sequence: ASNQDFMRF
What are the official names of this protein?
FMRFamide-4, SabFMRFamide-4.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPT5H_MOUSE
Sequence: MSDSEDSNFSEEEDSERSSEAEEAEVEEDQRSAAGSEKEEEPEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMSLKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVVTESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEGQHGGFGSPGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA
What is the function of this protein?
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.  DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.  DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter.  Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex.  DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II.  TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme.  Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT5, DRB sensitivity-inducing factor large subunit, DSIF large subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGB_STAAR
Sequence: MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFINEALSNQQIEPHFVNGLRVTDKATMTITKHTLIADVNTALVAQFNQQQCSAIGLCGLDAQLFEIKRFDQQYGYVGVPTTLNIDSLSYLCTKFVPIINSIGFNNHDGEFYNINADTLAYFIAASLEAPIYVLSNIAGVLINDVVIPQLPLADINQYIEHGDIYGGMIPKVLDAKNAIKNGCPKVIIASGNKPNIIEAIYNNDFVGTTILKSSV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERG_ASPTN
Sequence: MSSSTLEGQETASHHSKNSPSRHGDDGGLQTAGDEYVYIADHYGMVRRMIFIMTVCSSMFTNQLGLCNSLSTLEEIGESFGVTDPGKLSWTISGYGLTLGTFILIGGRLGDEFGNKAIFVIGMGWLALTSMMAGVSVYAGYPVYILARVLQGLGPALTVPNALAIMGKCFSEHPRNMGFAWFAASAPVGAMAGLLFGPLFTMAWWPWIYWSQALGVAFVFALSIVAIPNMPAESEQKQRRTILEILERIDLLGGACGVTALVLFNFAWNQSLVATWKEPYVYVCLILSFLFLAAFFYVELRVARHPILPVAVLTSDIAFVFGCTAAGWSTFGIWLFYVIRICLNIGGQTPIQMAAWLSPILVTGIGTALIVGKIITKVPASSIMLFAMLCYFITSLLMALRPVHSIYWTYFFFATIIATFAMDSSLPAATIIFANAVPRQYQGMGSSVIMTIVVYSISLGLGFAGTIELQINNGGHTKADLLHGYRGTLWFSVGLTAFGTVLALIFLLKDLRRRKLARTQVEEEKGHSSEA
What is the function of this protein?
Efflux pump that might be required for efficient secretion of terrein or other secondary metabolies produced by the terrein genne cluster (PubMed:24816227).
What are the official names of this protein?
Efflux pump terG, Terrein biosynthesis cluster protein terG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COBQ_RHIWR
Sequence: MGAVMLQGTGSDVGKSVLVAGLCRAFVRRGLAVRPFKPQNMSNNAAVTIDGGEIGRAQALQAIACRVEPHSDMNPVLLKPQADRTSQLVVHGRVRGTLGSADFREARRPLLDEVLASYRRLREQCDIVVVEGAGSPAEINLRAGDIANMGFARAAGVPVVLVGDIDRGGVIAAVVGTRAVLDPADAAMIHGFLINKFRGDPALFEDGYRQIEALSGWRGFGVVPWLAATARLPSEDAVILERRGGPAEGRVLVACPILPRISNFDDLDPLKLEPGVELVMVPPGRPIPAEAALIVLPGSKATIADLAALRAEGWDIDIRAHHRRGRAILGLCGGYQMLGRRVADPEGIEGPPGAVDGLGLLDVETRLSPAKTLRRVEGEALDARFDGYEMHVGETDGPGRARPFARFDDGRTDGAIDPGGTVMGSYVHGLLANADLRRALLARLGIEGGGRDYAASVDAALDAIAEEIERHVDVDALVALAQAGG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PLSX_STRPZ
Sequence: MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKINSYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTGALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSFYAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVADVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLDYSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVND
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ACHA4_CHICK
Sequence: MGFLVSKGNLLLLLCASIFPAFGHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPQEYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRIKWMPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLVSMHSHVDQLDYWESGEWVIINAVGNYNSKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPRTHTMPDWVRRVFLDIVPRLLFMKRPSTVKDNCKKLIESMHKLTNSPRLWSETDMEPNFTTSSSPSPQSNEPSPTSSFCAHLEEPAKPMCKSPSGQYSMLHPEPPQVTCSSPKPSCHPLSDTQTTSISKGRSLSVQQMYSPNKTEEGSIRCRSRSIQYCYLQEDSSQTNGHSSASPASQRCHLNEEQPQHKPHQCKCKCRKGEAAGTPTQGSKSHSNKGEHLVLMSPALKLAVEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
Protein: NADK_THEP1
Sequence: MKIAILYREEREKEGKFLKEKISKEHEVIEFGEANAPGRVTADLIVVVGGDGTVLKAAKKAADGTPMVGFKAGRLGFLTSYTLDEIDRFLEDLRNWNFREETRWFIQIESELGNHLALNDVTLERDLSGKMVEIEVEVEHHSSMWFFADGVVISTPTGSTAYSLSIGGPIIFPECEVLEISPIAPQFFLTRSVVIPSNFKVVVESQRDINMLVDGVLTGKTKRIEVKKSRRYVRILRPPEYDYVTVIRDKLGYGRRIE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_VARPS
Sequence: MSAQEIKGLGMIPMVIEQSGRGERSYDIYSRLLKERIIFLVGEVNDQTANLVVAQLLFLESENPDKDISFYINSPGGSVSAGMAIYDTMQFIKPDVSTMCIGFAASMGAFLLAAGEKGKRFSLPNSKIMIHQVLGGARGQATDIEIHARDILRTKDQMNRILAERTGQPLEKVKSDTERDYFLTADEAKDYGLVDQVIAKRS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POMT1_HUMAN
Sequence: MWGFLKRPVVVTADINLSLVALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQIFFLDDSGPPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSNVPVWSLRLLPALAGALSVPMAYQIVLELHFSHCAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWWFWLTLTGVACSCAVGIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQMSQGVCVFCHLLARAVALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLRNVFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVKDPRRHQLVVSSPPRPVRHGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVSCYIDYNISMPAQNLWRLEIVNRGSDTDVWKTILSEVRFVHVNTSAVLKLSGAHLPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQEQRERERELHSPAQVDVSRNLSFMARFSELQWRMLALRSDDSEHKYSSSPLEWVTLDTNIAYWLHPRTSAQIHLLGNIVIWVSGSLALAIYALLSLWYLLRRRRNVHDLPQDAWLRWVLAGALCAGGWAVNYLPFFLMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRSQLQRSIFSALVVAWYSSACHVSNTLRPLTYGDKSLSPHELKALRWKDSWDILIRKH
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.  Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient (PubMed:12369018, PubMed:14699049, PubMed:28512129).  Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins (PubMed:28512129).
What are the official names of this protein?
Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FECC_ECOLI
Sequence: MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSAFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG
What is the function of this protein?
Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+).  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Fe(3+) dicitrate transport system permease protein FecC, Iron(III) dicitrate transport system permease protein FecC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACCA_SALTY
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLEGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.