PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_POLSJ
Sequence: MSVWALGLNHTTAPLDLRGRFAYALDQIEPTLRGLRESLARQPEATLLSTCNRTEIYCAGDHNDLEHTLEWLAHNGGVSPALLRSHAYTLQDDQAARHAFRVASGLDSMVLGEPQILGQLKDAVRAAEDAGAMGSTLHQLFQRSFAVAKEVRTSTEIGAHSISMAAASVRLAGQLFENLGDIRVLFVGAGEMIDLAATHFAAKTPKSMAIANRTLERGEKLASRFGAEVMRLADLPSRLHEFDAVISCTASTLPIIGLGAVERAVKLRKHRPMFMVDLAVPRDIEPEVKDLPDIYLYTVDDLAHVVQTGKDNRQAAVAQAEVIIDAGVQNFMHWLGQRRTVPLIQQLNAQTDEWRAAEIARAKKLIAKGEPMDAVLDALTRGLTQKMLHGALAELHAGDAASREATAHTVSRLFLRGQPPKEHKER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PG085_VACCW
Sequence: MIVLPNKVRIFINDRMKKDIYLGISNFGFENDIDEILGIAHLLEHLLISFDSTNFLANASTSRSYMSFWCKSINSATESDAIRTLVSWFFSNGKLKDNFSLSSIRFHIKELENEYYFRNEVFHCMDILTFLSGGDLYNGGRIDMIDNLNIVRDMLVNRMQRISGSNIVIFVKRLGPGTLDFFKQTFGSLPACPEIIPSSIPVSTNGKIVMTPSPFYTVMVKINPTLDNILGILYLYETYHLIDYETIGNQLYLTVSFIDETEYESFLRGEAILQISQCQRINMNYSDDYMMNIYLNFPWLSHDLYDYITRINDDSKSILISLTNEIYASIINRDIIVIYPNFSKAMCNTRDTQQHPIVVLDATNDGLIKKPYRSIPLMKRLTSNEIFIRYGDASLMDMITLSLSKQDISLKRNAEGIRVKHSFSADDIQAIMESDSFLKYSRSKPAAMYQYIFLSFFASGNSIDDILANRDSTLEFSKRTKSKILFGRNTRYDVTAKSSFVCGIVRGKSLDKTSLVEMMWDLKKKGLIYSMEFTNLLSKNTFYLFTFTIYTDEVYDYLNTNKLFFAKCLVVSTKGDVENFSSLKKDVVIRV
What is the function of this protein?
Probably involved in maturation of some viral proteins by processing them preferentially at Ala-Gly-|-Ser/Thr/Lys motifs.  Does not seem to be responsible for the cleavage of major core proteins.
What are the official names of this protein?
Metalloendopeptidase OPG085, Metalloendopeptidase G1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M44 family.
Protein: EX7S_BURCH
Sequence: MAKTASPGATPPGNGTEPLPDNYEMALAELETLVARMEGGALSLEDSLAAYRRGATLVAFCQQQLEKVEQQVRVLDGATLKPLSSGTAATDGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SOF1_NAJAT
Sequence: LKCHNTQLPFIYKTCPEGKNLCFKATLKKFPLKFPFKRGCADNCPKNSALLKYVCCSTDKCN
What is the function of this protein?
Potent inhibitor of hNav1. 8/SCN10A (IC(50)=141-380 nM) (PubMed:30804211).  Is highly selective for this channel and acts in a reversible manner (PubMed:30804211).  Shows a depolarizing shift of activation and hyperpolarizing shift of inactivation (PubMed:30804211).  In contrast to the very similar cytotoxin A5 (AC P62375), does not seem to bind integrin alpha-V/beta-3, since it does not promote or inhibit the proliferation of HUVECs and C-PAE cells (PubMed:30804211).  In vivo, in rodent models of inflammatory and neuropathic pain, it alleviates nociceptive behaviors more potently than does morphine (PubMed:30804211).  It displays no evident cytotoxic, hemolytic and cardiotoxic activities and produces no obvious adverse responses in mice even at a dose 30-fold higher than that producing a significant analgesic effect (PubMed:30804211).
What are the official names of this protein?
Mu-elapitoxin-Na1a, Mu-EPTX-Na1a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLD_RICTY
Sequence: MKSKNNKFIAMSIPFILGTALGIYVESTYYFTSIINQKSFALPDTQIKHYSIPELSRRNVSTCFTPPAGCTKFIVQQLEKAEESIYMQAYGMSDSLITTALINAQMRGVKVKILLDRSNLKQKFSKLYELQQAKIDVGIDTVPGIAHNKVIIIDKKKVITGSFNFTVAADKRNAENVILIEDQQLAESYLQNWFSRKASNSVHF
What is the function of this protein?
Could be a virulence factor.
What are the official names of this protein?
Phospholipase D, PLD, Choline phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_LEPBP
Sequence: MKIKTDEVTSVLKQEIKNFKKDLQVEEVGTVLEVGDGIARVYGLTNVMSGELVEFQNGVRGQAFNLEENSVGVVIFGDYIKIEEGFSVKRVGKIFEVPVGPELLGRVLNPLGEVIDGKGPLNAKKTRPVESPAPGIAMRKSVHEPMQTGIKAIDAMIPIGRGQRELIIGDRGTGKTSIAIDTIINQKGKGVICVYVAIGQKASTVASTIEMLREKGALEYTIIVSANASEPAPMLYIAPYSGATMAEYFMYEEGKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKFGGGSMTALPIIETQEGEVSAYIPTNVISITDGQIYLQSNLFASGLRPAVDVGISVSRVGSAAQIKAMKKVAGTLKSDLAQFRDLEAFAQLGTELDPVTQAQLDRGYRVLEILKQPNNSPTPVEEQVISIFAVTKGFMDVVPTAKVREFEAFLLKTMREQHPEILEEIRTAKEVKQEAALQKTIKSIVEHFLAKNN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFG_SINFN
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKGRDGKMRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRSVEMIKTRLGATAVVMQLPIGAESEFKGVVDLIEMNALVWRDESLGAQWDVVEIPADMKDKAEEYREKLIETVVEIDEAAMEAYLEGTYPDNDKIRELVRRGTIDVKFHPMFCGTAFKNKGVQPLLDAVVDYLPSPIDIPAIKGIDVKTEGEITRKADDNEPLSMLAFKIMNDPFVGSLTFARIYSGKLEKGTSVMNTVKEKRERVGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDEESGQTIIAGMGELHLDIIVDRMRREFKVEASVGAPQVAYRETITRQHEEDYTHKKQSGGTGQFARVKIVFEPNPEGEDFAFESKIVGGAVPKEYIPGVQKGIESVLSSGPLAGFPMLGVKATLIDGAFHDVDSSVLAFEIASRACFREAAKKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQIQGQESRGVAVVINAHVPLANMFKYVDNLRSMSQGRAQYTMLFDHYAPVPSNVAQEIQAKYSGQK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_SALTI
Sequence: MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: HMUDK_BPPM6
Sequence: MKYINVRGCNGSGKTTLLRCLARDPLCRVINVIVPDHKPIPVTYAPDGIAIIGDYTPAAAGATTAGLDRIKTQAAAKAVAELVGRDPDVKAVLFEGVVVSTIYGPWQEWSKANGGMIWAFLDTPLEVCLKRIQERNGGKPIKEDQVADKHRTIARVRDKALADGETVRDIHWETALKDIKAVIENLG
What is the function of this protein?
Phosphorylates 5-hydroxymethyluracil (5hmdU) into 5-phosphomethyl-2'-deoxyuridine (5-PmdU) on DNA as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  The phosphate is added internally to the DNA polymer (PubMed:34522950).  Also transfers glutamate to 5-pyrophosphoryloxymethyldeoxyuridine (5-PPmdU) to produce 5-Nalpha-glyutamylthymidine (Nalpha-GluT).  As a final result of the pathway of hypermodification, 5-aminoethyl-2'-deoxyuridine (5-NedU) substitutes for about 30% of thymidines in the viral DNA (PubMed:34522950, PubMed:29555775).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
5-hmdU DNA kinase, 5-hydroxymethyluracil DNA kinase, P-loop kinase, gp54.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family. 5-hmdU DNA kinase subfamily.
Protein: CLA4_CANAX
Sequence: MTSIYTSDLKNHRRAPPPPNGAAGSGSGSGSGSGSGSGSLANIVTSSNSLGVTANQTKPIQLNINSSKRQSGWVHVKDDGIFTSFRWNKRFMVINDKTLNFYKQEPYSSDGNSNSNTPDLSFPLYLINNINLKPNSGYSKTSQSFEIVPKNNNKSILISVKTNNDYLDWLDAFTTKCPLVQIGENNSGVSSSHPHLQIQHLTNGSLNGNSSSSPTSGLLSSSVLTGGNSGVSGPINFTHKVHVGFDPASGNFTGLPDTWKSLLQHSKITNEDWKKDPVAVIEVLEFYSDINGGNSAAGTPIGSPMINSKTNNNNNDPNNYSSTKNNVQEANLQEWVKPPAKSTVSQFKPSRAAPKPPTPYHLTQLNGSSHQHTSSSGSLPSSGNNNNNNSTNNNNTKNVSPLNNLMNKSELIPARRAPPPPTSGTSSDTYSNKNHQDRSGYEQQRQQRTDSSQQQQQQKQHQYQQKSQQQQQQPQQPLSSHQGGTSHIPKQVPPTLPSSGPPTQAASGKSMPSKIHPDLKIQQGTNNYIKSSGTDANQVDGDAKQFIKPFNLQSKKSQQQLASKQPSPPSSQQQQQKPMTSHGLMGTSHSVTKPLNPVNDPIKPLNLKSSKSKEALNETSGVSKTPSPTDKSNKPTAPASGPAVTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVEKAGQGASGNVYLAEMIKDNNRKIAIKQMDLDAQPRKELIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRNKRATMVGTPYWMAPEVVKQKEYDEKVDVWSLGIMTIEMIEGEPPYLNEEPLKALYLIATNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQHKSGKIEELAPLLEWKKQQQKHQQHKQETSDTGFA
What is the function of this protein?
Essential for virulence and morphological switching (hyphal formation) of C. albicans.
What are the official names of this protein?
Serine/threonine-protein kinase CLA4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: PSBL_CAPAN
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PKSB_BACSU
Sequence: MNLTYKVHPIKTRYQGWTNYCYIIEDIVSRSAIVVDPSWELSKITTTLSELEAELKAVALTHSHYDHVNLVDPLTKMFNAQVYMSKKEIDYYQFRCRNLISLDDHQTISIGNTRAQCLLTPGHTAGGMCYLFSESIFTGDTVFTEGCGICEDDGSSAEEMFDSIQRIKSEVSPHVRVYPGHSFGKSPGHSIKDLYQHNIYFQIDKKEYFVKFRTRKNQKGIFDFK
What is the function of this protein?
Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
What are the official names of this protein?
Probable polyketide biosynthesis zinc-dependent hydrolase PksB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAT1_LACTA
Sequence: MKYFVVALALAVALVCIAESTAYDVNEELENELDDLSDAAWLAKAAEDLQALDDFEESEESRSMWSGMWRRKLKKLRNALKKKLKGEK
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria (A. globiformis VKM Ac-1112 (MIC=0. 5 uM), and B. subtilis VKM B-501 (MIC=1. 0 uM)), Gram-negative bacteria (E. coli DH5-alpha (MIC=1. 0 uM), E. coli MH1 (MIC=0. 7 uM), and P. aeruginosa PAO1 (MIC=4. 1 uM)), and yeasts (P. pastoris GS115 (MIC=17 uM), and S. cerevisiae Y190 (MIC>33 uM)).  Has a moderate hemolytic activity against rabbit erythrocytes.  Causes paralysis, but is not lethal when injected into insect (M. domestica) larvae.
What are the official names of this protein?
M-zodatoxin-Lt1a, M-ZDTX-Lt1a, Latarcin-1, Ltc-1, Ltc1.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 03 (latarcin) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDLA_PENCA
Sequence: MRLSFFTALSAVASLGYALPGKLQSRDVSTSELDQFEFWVQYAAASYYEADYTAQVGDKLSCSKGNCPEVEATGATVSYDFSDSTITDTAGYIAVDHTNSAVVLAFRGSYSVRNWVADATFVHTNPGLCDGCLAELGFWSSWKLVRDDIIKELKEVVAQNPNYELVVVGHSLGAAVATLAATDLRGKGYPSAKLYAYASPRVGNAALAKYITAQGNNFRFTHTNDPVPKLPLLSMGYVHVSPEYWITSPNNATVSTSDIKVIDGDVSFDGNTGTGLPLLTDFEAHIWYFVQVDAGKGPGLPFKRV
What is the function of this protein?
Hydrolyzes mono- and diacylglycerol but not triacylglycerol.
What are the official names of this protein?
Mono- and diacylglycerol lipase, MDGL.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: TRPC_PROMA
Sequence: MEIRRRPPNPKVKVANLEYAIPHEESEPRNILEKIVWEKDREVELARHRLPLPKLIAKIEKLSDTKNFLQTLKDSVTSPAVIAEIKKASPSRGLIREDFKPGDIAIAYQKGGATCLSVLTDKTFFQGGFDVLADVRKIIDIPLLCKDFILHPYQIYQARASGADAILLIAAILSDQDLMYLNKIALSLGLSILVEVHDAAELNRVLRLGGFPLIGINNRDLKTFETDLTTTCKVATECSNLLKEQDVLLVSESGIFTREDLQKVASFGASAVLIGESLMRQKDLTNALKELIG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: QUEC_PYRAE
Sequence: MIVEKPCRVVAVVSGGPDSTCYTALWLKRGCDVHALSFLYGQKAVVEVERAQLLLRRLDGIAAERGWGRVVEHRVVDLSSLGELWRGTQLTDPSVSVEQSYTPTVVVPIRNVVMAAVATAYAYTVGRNAGAKTYVILGSHYDDIKPREDTWEPLYPDCSPECVEAMQTAFRICHFRGERGVEIWTPSREGLRKSQLLKMCHQEVGDLIYDTWSCYKSGEAHCGSCESCKNRHAAFIEAGLPDCTAYLTPPGPGFEKRGQFYLHISCKKQ
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PTK7_DROPE
Sequence: MDMDVMMISMCILASTLMAPGWASTSGFLRVPQSQSIVENEAADFGCEATDPASYLHYEWLHNGREISYDKRVYRIGSHLHIEAVQREEDVGDYVCIATSLASGAREASPPAKLSVIYLESASVQLLGSNRNELLLKCHVEGASGDEPLQIEWYRDSARLASWGNVHLEEHRLLVRQPSPSDDGLYRCTASNAAGRVMSKQGYVYQANIKCLPRLLKKNQKLPESWGKQTFLCRGKRGGSGGLDQALSPAPEDLRIVQGPAGQLLIKEGDSAALSCLYELPAELQNQRIQLRWRKDGKLLRHVELGGAIPIPGHAHDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEGHAPLNSSPGLLEVIEQLKFVPQPTSKNLELDAAVAKVHCKAQGTPSPQVQWLREGSLNSSLPDQVEVDINGTLIFRNVRAEHRGNYTCQARSSQGQISATVSINVVVTPKFSVPPVGPIETTEQGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFSFLENGTLEIRNVQVEDEGSYGCTIGNSAGLKREDVQLVVRSTGDGFAPEETGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNELSIKEAGGDQPDASVTNGKGSEQEPCLSKQRNGASGKPKSKSNGDAQKSDDTACSQQSRSSKKSVYEQLVLPRSGLSELLQIGRGEFGDVFVGKLKASLVAASAQSDKDADTEKQHSNSENGSGGSGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEPEQSALEQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCVISSEFVVKVSYPALCKDKYSREYHKHRNTLLPVRWLAPECIQEDEYTTKSDIFAYGVLVWELFNQATKLPHEELTSEQVIQRSQAGTLEWTVAEATPDSLKEILLSCWLANPKERPSFSQLGSALSKAMQSVAEK
What is the function of this protein?
Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system.  Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage.  Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase-like otk, Tyrosine-protein kinase-like 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: EGT_NPVAC
Sequence: MTILCWLALLSTLTAVNAANILAVFPTPAYSHHIVYKVYIEALAEKCHNVTVVKPKLFAYSTKTYCGNITEINADMSVEQYKKLVANSAMFRKRGVVSDTDTVTAANYLGLIEMFKDQFDNINVRNLIANNQTFDLVVVEAFADYALVFGHLYDPAPVIQIAPGYGLAENFDTVGAVARHPVHHPNIWRSNFDDTEANVMTEMRLYKEFKILANMSNALLKQQFGPNTPTIEKLRNKVQLLLLNLHPIFDNNRPVPPSVQYLGGGIHLVKSAPLTKLSPVINAQMNKSKSGTIYVSFGSSIDTKSFANEFLYMLINTFKTLDNYTILWKIDDEVVKNITLPANVITQNWFNQRAVLRHKKMAAFITQGGLQSSDEALEAGIPMVCLPMMGDQFYHAHKLQQLGVARALDTVTVSSDQLLVAINDVLFNAPTYKKHMAELYALINHDKATFPPLDKAIKFTERVIRYRHDISRQLYSLKTTAANVPYSNYYMYKSVFSIVMNHLTHF
What is the function of this protein?
Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.  Acts on the host at the organismal level to block its development, thereby increasing the yield of progeny virus.
What are the official names of this protein?
Ecdysteroid UDP-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ISCS_BUCAI
Sequence: MKTPIYLDYAATTPVEFEVAKKMMNYLTIDGVFGNSASRSHKFGWKAEEVVDIARNQISELIGADSREIVFTSGATESNNLAIKGIASFHQNKGKHIVTSKTEHKSVLDTCRYLENKGFTVTYLTPKNNGIIDLNNLKKNIKKDTILVSIMHVNNEIGIIQDINSISQICRNHGVFFHVDATQSVGKIPIDLKKIPIDLMSFSAHKIYGPKGIGGLYVRRKPRVRLLSLIHGGGHERGMRSGTLPVHQIVGMGESFVLAKRKIHDDFIHLTKLKNILWNGIKNIEEVYLNSDLQQGAPHILNVSFNYVEGESLIMALKDLAISSGSACTSASLEPSYVLKSLGIRDELAHSSIRFSIGRFTTEKEIIHAIKLVHKSIHRLRELSPLWEMFKSGVDLNSIEWDHV
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2633_MYCTU
Sequence: MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI
What are the official names of this protein?
Uncharacterized protein Rv2633c.
Protein: VQ9_ARATH
Sequence: MDKSCNSSGDSSAVSASATSSTGNNTTNRDHYLRQLNKLSHKISKPTNSSSSVSVANREIDLPPPPPLQINQGNLHQHQPPVYNINKNDFRDVVQKLTGSPAHERISAPPQQPIHHPKPQQSSRLHRIRPPPLVHVINRPPGLLNDALIPQGSHHMNQNWTGVGFNLRPTAPLSPLPPLPPVHAAAESPVSSYMRYLQNSMFAIDSNRKEFSGLSPLAPLVSPRWYQQQENAPPSQHNSFPPPHPPPPSSAVSQTVPTSIPAPPLFGCSSSPKSPYGLLSPSILLSPSSGQLGFPVSPTTVPLPSPKYKGH
What is the function of this protein?
Functions as a negative regulator of salt stress response.  Functions as repressor of WRKY8 transcription factor by decreasing the DNA-binding activity of WRKY8 and acts antagonistically with WRKY8 to regulate sodium and potassium homeostasis under salt stress.
What are the official names of this protein?
VQ motif-containing protein 9, AtVQ9.
Protein: ETHR_MYCTU
Sequence: MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
What is the function of this protein?
Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).
What are the official names of this protein?
HTH-type transcriptional regulator EthR.
Protein: DAPE_COXBR
Sequence: MSETLNLLKQLIERPSITPNDAGCQTILIDRLKSVGFQCEHLPFGEVHNFWAWHGHQSPFIIFAGHTDVVPPGDETQWHSPPFTPTEKNGYIYGRGAADMKSGLAAMVVAAENFVKQNPDHNGTIGFIVTSDEEGPAENGTQKVVDYLQQKNIKLDYCIVGEASSNEKLGDAIKIGRRGSMHGELTIIGKQGHIAYPHLADNPIHRSFQAFEALAKTKWDEGNEHFTPTSFQFYNVEAGAGAANVIPATLKAKFNFRFAPIHTTQQLQQKVERILNYYQLNYDIQWNVSSQPFFSGNGRLATFVRQAIQEICHLNTEPNTYGGTSDGRFIATTGCEVIELGPVNKTAHHVNENICIADLEKLTDIYFRTLQLLI
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MB3R5_ARATH
Sequence: MSSSSNPPVCSPEKEERSEMKIEIQCMENKQPLAASCSSASEGSGCFFLKSPEIATPATVSSFPRRTSGPMRRAKGGWTPEEDETLRRAVEKYKGKRWKKIAEFFPERTEVQCLHRWQKVLNPELVKGPWTQEEDDKIVELVKKYGPAKWSVIAKSLPGRIGKQCRERWHNHLNPGIRKDAWTVEEESALMNSHRMYGNKWAEIAKVLPGRTDNAIKNHWNSSLKKKLEFYLATGNLPPPASKFIVLKDIADGDRDSKQSSATKPFKDSDSLTQTSSGNTDSNEVGRDHFDSSSALLEEVAASRRIGVNEYACSPVEYKPQLPNLEPISEEVRINSKAYFERSIQRKVENGFGTPKHGNLYYKSPLDYYFPSEADLQHMYGYECGCSPGAASPVSLMTTPCNKDSGLTATRSPESFLREAARTFPNTPSIFRKRRKVVLAAKTDAVVVVNGVVKEVDRKEESKDMRKSLLLETTDNCSDDEELGLNGNAFNLSPPYRLRAKRTAVIKSRQLEFTSEKEKQPDNEIEFTSAKEKQPDNEIKTSEEDKPV
What is the function of this protein?
Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity).  Transcription repressor that regulates organ growth.  Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325).
What are the official names of this protein?
Transcription factor MYB3R-5, Myb-related protein 3R-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALLB_SOLUE
Sequence: MSECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLHFNEPGRTEWEGAATGSRALAAGGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFALWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRADDLTLYEGMREAARLGLPVAVHAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISSGRGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVLGGIVDVVASDHSPAPPAMKTGDDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELTAGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESLWQKHPVNPYTGNSFRGSIRRTMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.