PharMolix/UniProtQA huggingface dataset:
Protein: BCHL_RHOPA
Sequence: MNILTDPNKLKTSGCADVNASKCAEGDGEGSVQVQLDPNLNIGTAKVFSIYGKGGIGKSTTSSNLSVAFSKLGKRVLQIGCDPKHDSTFTLTKKLMPTVIDVLESVNFHSEEVRPEDFVFEGYNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFASPLQHSERAMIVAANDFDSIFAANRIAAAIQAKSKNYAVRLAGVIANRSRETDQIDKFGERTGIKRVAHLPDLDVIRKSRLKKMTLFEMDHTPEIEAVQNEYLRLATELWEAKEPPVQGKPLKDRDIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: FBSB_PROM1
Sequence: MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGERDEAPMLYIGEEVGSGTGPGVDFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYMNKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIVVMDRARHKNLVSEIRSTGARIQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQTSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKDCTRTSSLVISTLDQTARFTNTVHIKDGAQSISLK
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: ROX_RHOHA
Sequence: MSDVIIVGAGPTGLMLAGELRLQGVDVVVVDKDEEPTQFVRALGIHVRSIEIMEQRGLLDKFLAHGRKYPLGGFFAGISKPAPAHLDTAHGYVLGIPQPEIDRILAEHATEVGADIQRGKRVVAIRQDTDNVAAELSDGTTLHARYLVGCDGGRSTVRKLRSTSVFPASRTSADTLIGEMDVTMPADELAAVVAEIRETHKRFGVGPAGNGAFRVVVPAAEVADGRATPTTLDDIKQQLLAIAGTDFGVHSPRWLSRFGDATRLADDYRRDRVFLAGDAAHIHPPMGGQGLNLGVQDAFNLGWKLAAEINGWAPVGLLDTYESERRPVAADVLDNTRAQAELISTAAGPQAVRRLISELMEFEDVKRYLTEKITAISIRYDFGEGDDLLGRRLRNIALTRGNLYDLMRSGRGLLLDQGGQLSVDGWSDRADHIVDTSTELEAPAVLLRPDGHVAWIGDAQAELDTQLSTWFGRSARDRA
What is the function of this protein?
Monooxygenase that can modify rifampicin, thereby inactivating its antibiotic activity.
What are the official names of this protein?
Rifampicin monooxygenase, RIFMO.
What is the protein family that this protein belongs to?
Belongs to the rifampicin monooxygenase family.
Protein: SMI19_BOVIN
Sequence: MPGGYGVMGDDGAMDYSVHEAWNEATNVYLVVILVSFGLFMYAKRNKRKIMRIFSLPPPAETLSEPNFYDTISKIRLRQQLEMYSISRKYDYQQPQSQADSVQLSLE
What are the official names of this protein?
Small integral membrane protein 19.
What is the protein family that this protein belongs to?
Belongs to the SMIM19 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LPTD_HAEI8
Sequence: MNKKHTLISLAILTALYSQQSLADLHEQCLMGVPKFSGEVVTGDVNSLPVYIEADNAEINQPNDATYQGNVDLKQGNRHLLAQSVQVKQSGNQSTPLRMAYVRNGFDYKDNQINMLGKDAEFNLDSHDGNLTNSEYEFVGRQGRGKADNITLHNNYRVMKNATFTSCLHGDNAWAVDASEIRQYVKEEYAEMWHARFKIHGVPVFYTPYLQLPIGDRRRSGLLIPSAGTSNRDGLWYAQPIYWNIAPNYDLTFTPKYMSRRGWQANGEFRYLTSIGEGKVAGEYLGKDRYSEYASDNRKRHLFYWNHNSSFLQNWRLNINYTRVSDKRYFNDFDSIYGRSTDGYANQYARIAYYQPNYNFSLSAHQFQIFDDIVNIGPYRAVPQLDFNYHKYDLANGWLNFKLHSQAVRFDNDSKLMPTAWRFHAEPSLNSLMSNKYGSLNIETKLYATRYEQKKGSGKNAEDVQKTVNRVIPQFKVDLQSVLSRDITFLKEYTQTFEPHVQYLYRPYRNQSNIGSTLNNDYLGFGYDSALVQQDYYSLFRDRRYSGLDRISSANQVTLGGTTRFYDIAGEERFNLSAGQIYYLSNSRIDENPANKTPTSSSAWALESNWKISNKWYWRGSYQFDTHTNSTSLANTSLEYNPEKNNLIQLNYRYVNQEYIDQNLGKSANAYQQDIQQVGLVVGWEIANNWAVVGRYYQDLALQKPVEQYLGVQYNSCCWAASVGVKRNVTNHQNQTRNEIVYDNSIGITLELRGLGSNDHQSGIQEMLEKGKLPYIRAFSLD
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: NDC1_YEAST
Sequence: MIQTPRELLNPRYTYHTIFSDVCKTRFNHLVTRLFFICSIIQTVVISLLALPHSPLWELALAFIPNILALNLVSLLIIVTRKNYMHVKNFGFANSLTFILGQLLSVKFLVYQGVYSMGSILLSFVLGVVFGRGGSGWKPYYKLFIWLVVPTIYNLQHHVTDADKLSFNCENFFQAPQDYVLERVKRIMEKSVILSVISMFVLPIFTTVFFSRQKSGLFDSFTNGVLAVTNLLIISCIIFITFEFINIAFDAHMSIGCLHKGKLISNLSSTPMETLLSGLSADKPFTRLTAYQELAYRATSLDPSLRAPIYHSKFRSSSGNTWSLILNECLKTIQINNEKVVQYLRSVQDLGGSATARHKKKVENLDYMYENGKLTSANERLFGNRPSMMAPLRDNGLLDESPNRLRVRTDDSVLLNRGNKKRHRSSYYDNDLDETTQTFNGSIFTHETTFMTAMRLMLKKLKNSIMSFIFPSYAERQSSDESDNYRLLPNGSNKAQISIIDIWSISKKRQAEKLVPLPICHANSVVALTGLLIRSKTEDPKGGIIASVGDILKTLERSICALGEFADWDPESMAYTAFQTQRTAQDRVQQDSEDEDSMKDTTDMISVLYQLSTSAFMEIVLEYNVALNDVYLDADVAKLANWFLEVYASGNPNAT
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC) and the spindle pole body (SPB), probably by playing a key role in de novo assembly and insertion of both structures in the nuclear envelope.  In SPB duplication NDC1 is required for the insertion of the cytoplasmic side of the SPB in the nuclear envelope, thus allowing for the assembly of the nucleoplasmic SPB side.  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
What are the official names of this protein?
Nucleoporin NDC1, Nuclear division cycle protein 1, Nuclear pore protein NDC1.
What is the protein family that this protein belongs to?
Belongs to the NDC1 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Central core structure of the nuclear pore complex. Spindle pole body, central plaque.
Protein: GPDA_HYPNA
Sequence: MTQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLKPEIRATNKLEDLGLADAIFAVAPAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMTQVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTRLGTELIQAISTPTFRPYLGTDLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGLSGLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIEMPICEAVAAVIEGEITVDDAITALLMRPVKAEAVKP
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_ACTP2
Sequence: MAGTTAEYISHHLSFLASGDGFWAVHLDTLFFSLLAGVIFLFVFSRVAKNATSGVPGKLQCFVEIVIGWVDGLVKDNFHGPRNVIAPLALTIFCWVFIMNAIDLVPVDFLPQLANMFGIHYLRAVPTADISAPLGMSICVFFLILFYTVKSKGFGGLVKEYTLHPFNHWVFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYMADNFALQALGIPLHLVWAIFHILVITLQAFIFMMLTIVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTSR_GEOSE
Sequence: MPNISDIIEQYLKQVLNMSDQDIVEIKRSEIANKFRCVPSQINYVINTRFTLERGYIVESKRGGGGYIRIMKVKTKSEAQLIDQLLELIDHRISQSSAEDVIKRLMEEKVISEREAKMMLSVMDRSVLYIDLPERDELRARMLKAMLTSLKYK
What is the function of this protein?
Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB, by acting as a repressor of these class III stress genes.  After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon.  CtsR negatively autoregulates its own synthesis (By similarity).
What are the official names of this protein?
Transcriptional regulator CtsR, Class three stress gene repressor.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: PYRD_RHOP5
Sequence: MIRAFDALSLPLLRLLDPEDAHRLAIQGLRLLPQAAPPADQPNLSVRAFGLNFSNPVGIAAGFDKNAEAPDALLRMGFGFVEIGTVTPKPQSGNPRPRLFRLERDEAVINRMGFNNDGGEVVLRRLAARSARGGIVGVNVGANKDSEDRVADYVRLIEMFAPVASYFTVNVSSPNTPGLRNLQQAAALDDLLAKVIEARERVRAIAGDTPVLLKIAPDLTLNELDDVVHIARSRKVDGMIVANTTLSRTHTLREQARAKEQGGLSGRPLFRLSTRMVAETYVRAEGAFPLIGVGGIDSGGAALTKIRAGASLIQLYSALIYKGLGLVESIKQDLASTLLRTGRDQLSEIVGADAPMITAEDWPV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YA4A_SCHPO
Sequence: MDQVLSKVTTTAATYATAYAVRTGLQLAGSLVAKRFSKYIQTSAPKSSQFNLELVKSRLEQKIQAITPAVDLIQLVAARGNSSLQNLVPLIIRLRDHIDDFLEFIDYEASGSEKKSPEKADEASEKIFRRCEVLLREIEETIPLINLSLTTAGITLNTALSNTISPSRLLQAQCFLELSDKRFEESHTEIQIGPKFTVVLYTSFSQPSKSDGPLDVRWQETFAKSDLYIKRVVSASQKFSYVICIDEDLNDGRYHEETVGKPTSAPVFGKKLEISLQRMSLLCYTVSGRLLNISQAKSPVLALQLTSIKDVSALDKAHQDNSEDLNNPFIKNNDKTKFHQNIDWIALEKYFEVNALDISDSESEDLSDILSDSEFSIGNRNKNIGNNEYSAQISSDPAEEEIANAMHSLKLEPETSIYLTNPGSLSLLEYLLRLCSLQELHQISCLEMTDSQLAAMLNSN
What are the official names of this protein?
Uncharacterized protein C31A2.10.
What is the protein family that this protein belongs to?
To yeast YGL164c.
Protein: Y1259_SODGM
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDVGSNPRLRAAVDKALANNMTRDTLNRAIARGVGGGDDAQMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKRGVISFAPGLSEDTIMDAALEAGADDVITYDDGAIDVYTTPEAFGEVKDALEAAGLTPEASEVALVPSTRTDLDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein SG1259.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_PSET1
Sequence: MNIRTILVEKAIAAMTTVGLPADTNPAVTQSTRPQFGDYQINAAMGAAKKMKSNPRELAQKIIDNLDVSDIAEKTEIAGPGFINIHLKPEFLAQSVKAANSDAKLAVNEHANPQKVVVDYSSPNLAKEMHVGHLRSTIIGDAIVRALEFRGDSVVRQNHMGDWGTQFGMLIAHLEDQISQGVDLDTVALADLETFYRDAKKRFDDEEGFADKARNYVVKLQGGDAHCEKLWKLFIATSVKHSEEVYKRLNVTLTQADIMAESAYNAELNDIISLLKDKNIAVESQGAQVVFLDELANKDGEPSAFIVQKSGGGFLYATTDLAACDYRSNKLGADRILIFVDARQSLHFNQVELTARKAGFLRDETSYEFCPFGTMMGADNKPFKTRTGGTVKLADLLEESINRAAIKLAERESDLSEQERSEIARKVGIGAVKYADLSKHRTSDYIFNWDSMLSFEGATAPYLQYAYTRIRSIFRKSGVDAATLNSNVTIVEPQEKALALKLLQLEEVLDLMITEATPHVLCGYLYELASLYMTFYEACPVLKEGVEPNVRDSRLVLCNLVSKTLETGLDLLGIEVMEQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOG2_MOUSE
Sequence: MRCGGGARACRRACRCWLSGYAGPADGTQQPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV
What is the function of this protein?
Mitochondrial polymerase processivity subunit.  It regulates the polymerase and exonuclease activities promoting processive DNA synthesis.  Binds to ss-DNA.
What are the official names of this protein?
DNA polymerase subunit gamma-2, mitochondrial, DNA polymerase gamma accessory 55 kDa subunit, p55, Mitochondrial DNA polymerase accessory subunit, MtPolB, PolG-beta.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PEND_PENTH
Sequence: MPLSSKVSQAPWSLTGKTAVVTGGSRGIGRAIAIHLARKGVRKLAITYVRDLASAESALEEIRKEGIETGIAIQADILNASVGRDLIAQALVGLETSTIDILVNNAALLDPINTPSVEDVTLENFQELMQANCFAPVSIINACMPHLPPSGGRVINISSVASKTPNPGTIVTYGASKAALDSYTRSMAGLFAKDKTATFNTVCVGPTVTDSFRAVSQLYPGEFIKEVAKSFTAADRVGVPEDIAYIVGFLASEEGRWMNGACVSANGGLREALPALS
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of penigequinolones, potent insecticidal alkaloids that contain a highly modified 10-carbon prenyl group (PubMed:25859931, PubMed:28114276).  The first stage is catalyzed by the nonribosomal pepdide synthetase penN that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin (By similarity).  4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase penM through dehydrogenation to form a double bond between C-alpha and C-beta of the O-methyltyrosine side chain (By similarity).  PenM also converts its first product methoxydehydrocyclopeptin to 4'-methoxycyclopenin (By similarity).  The following conversion of 4'methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase penL (By similarity).  4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B (Probable).  The prenyltransferase penI then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase penH to yield conjugated aryl diene (PubMed:25859931).  The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase penG to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain, or undergo cyclization to yield yaequinolones J1 and J2 (PubMed:25859931).  The conversion of the styrenyl quinolone into the tetrahydrofuran-containing yaequinolone C is performed by the FAD-dependent monooxygenase penE and involves epoxidation of the terminal C7'-C8' olefin, followed by epoxide ring opening initiated by the C3' hydroxyl group (PubMed:25859931).  The predicted cysteine hydrolase penJ acts as an epoxide hydrolase that enhances the rate of the 5-exo-tet cyclization step, increasing the yield of yaequinolone C (PubMed:25859931, PubMed:28114276).  PenF catalyzes the cationic rearrangement of the epoxide formed by penE (before ring opening to produce yaequinolone C) into yaequinolone D (PubMed:28114276).  Finally, the short-chain dehydrogenase/reductase (SDR)-like reductase penD, catalyzes both the dehydration of yaequinolone D and the reduction of the resulting oxonium to yield penigequinolone (PubMed:28114276).
What are the official names of this protein?
Short chain dehydrogenase penD, Penigequinolones biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NDHK_DIOEL
Sequence: MNLIEFTLLDQTTPNSVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMAEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISREISEDRVMSQRENRSFTTNHKFDIRRSTHTGNYDQGLFYQSSYTSEISSKRFFKSKNSVSSHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CCA_STAAR
Sequence: MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDITTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFVRDLYEDLQRRDFTMNAIAMDTANKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMIRCLRFQSQLSFDIATETFEAMRTQMADIKFLSIERIVIELTKLMRGINVEKSFNHLKSLKAFNYMPYFEHLDMNQINVTEPIDLELLIAIVSVKFDINYSLKPLKLSNRQVKDINQYIQIMNALPSIITKEQLKMFVYDYDTNLIKNVMVAADVLKANDIQGHEPLIVNLQTIDETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDLLRQIEIAIVTGKVSNEETEILKWVDNHVKI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: RUXE_DANRE
Sequence: MAYRGQGQKVQKVMVQPINLIFRYLQNRSRISVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEVHMKTKNRKPLGRIMLKGDNITLLQSVSN
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  As part of the U7 snRNP it is involved in histone 3'-end processing.
What are the official names of this protein?
Small nuclear ribonucleoprotein E, snRNP-E, Sm protein E, Sm-E, SmE.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: ENGB_HELPG
Sequence: MIVIKDAHFLTSSSQLFQCPASLTSEMVILGRSNVGKSSFINTLLGKNLAKSSATPGKTRLANFFSTTWEDKENALTTTFNVIDLPGFGYAKVSKSLKKEWEGFLWELLSVRISIKLFIHLVDARHLDLEIDKNAKENIQALLRPDQAYLSLFTKFDKLNKNEQHRLFLNAPKPFLINTTHFNALSSKYPTLEIVRQTLLKYLLTNPL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: DEF2_SHEON
Sequence: MFKDEMRQTPNKPLPIAVVGEAILKQQAIEVRDFDDTLSQLASQMAASMVEAKGVGIAAPQVHSPLALFIMASRPNERYPDAPLMEPLVVVNPQIVLRSLQLEKGEEGCLSVPGQRFTIWRPQTIVVRYQNLAGQWQHSELTGFIARIFQHEFDHLQGITLLERSQMPEQKLMAQEGKPQA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: VPS10_YEAS6
Sequence: MILLHFVYSLWALLLIPLINAEEFTPKVTKTIAQDSFEILSFDDSNTLIRKQDASVTISFDDGETWEKVEGIEDEITWIYIDPFNRHDRAVATSMYESRLYITNDQGKSWERITLPDSEKNISSRGCYIETHPLNKNYFLAKCNYCEKTEVDNEENSGDEEGAPVIFNITHCTDKVFASNDGGKSFSEIKSSLERNENSAISISDCGFAKTGKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVITQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINLYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKNKGVTKISVDNGLTWTVLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIRRFDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLSSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHVISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDALPEGNEENIDRPDSTAPSNENQ
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.  Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein PEP1, Carboxypeptidase Y receptor, CPY receptor, Carboxypeptidase Y-deficient protein 1, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10, Vacuolar protein sorting-associated protein 10, Vacuolar protein-targeting protein 1.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: TRMN6_PSEA6
Sequence: MKRQGFQFKQFFIEHQDCAMKVGTDSIMLGSWVTGGDLINASETQRFLDIGTGSGLLAIMLAQKSSEQTHISGIDIDKDAIGQATRNMANSPWSHRLDAQQASVQSFTQNCDNPKFALIISNPPYFNSPILTHEKQAQKRVAARQTSELTHHTLLNNVVRLLAPSGVFYCVLPSDVSQAFIELADPLGLSLIKQLTVFSKPDTNALRELLAFRFNDPSCIRDTISRALTSPEPPTRDTLTIYTQSHQYSDQYKALCKDYYLNF
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4E1_SCHPO
Sequence: MQTEQPPKESQTENTVSEPQEKALRTVFDDKINFNLKHPLARPWTLWFLMPPTPGLEWNELQKNIITFNSVEEFWGIHNNINPASSLPIKSDYSFFREGVRPEWEDVHNKTGGKWAFQNKGRGGNALDEMWLTTVLAAIGETLDPTGQEVMGVVINMRKGFYRLAVWTKSCNNREVLMEIGTRFKQVLNLPRSETIEFSAHEDSSKSGSTRAKTRMSV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1, eIF-4E-1, eIF4E-1, eIF-4F 25 kDa subunit 1, mRNA cap-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.