PharMolix/UniProtQA huggingface dataset:
Protein: HIS5_NOSP7
Sequence: MPVIAVVDYEMGNLHSVCKGLEKAGATPNVTYSPKELEQADAIVLPGVGAFDPAVQHLRARGLEQPIKDAIASGKPFLGICLGLQILFESSAEGTQPGLGIIKGKVRRFRPEPDITIPHMGWNQLEMTQAKSILWEHLPSDPWVYFVHSYYVDPIDPLIRAATITHGTQTVTAAIAHENLMAVQFHPEKSSNIGLQILSNFVAQVREKIPA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_HAEIN
Sequence: MAISRLLVEKFRNLTAVDLDFDPCFNFLIGNNGSGKTSLLEAIFYLGHGRSFKSAVTNRIISYDEPHFTLFGQIQESQHQWSIGLQKLRQGNTLVKINGEDGNKISDLAHLLPMQLITPEGLTLLNGGPSYRRAFLDWGLFHHQTSFYSAWSNLNRLLKQRNAALAQNQPYSAIKIWDVELAKLAHQVSEWRAEYAEALSPEIEQTCQLFLPELEINVSFHQGWEKNADYYEILQQNFERDRALNYTFSGPQKADFRFKAQGLPVEDVLSRGQLKLLMCALRLAQGEHLMKEKQRHCIFLIDDFASELDQYKRALLAERLQQSGSQVFVTAITQRQLKEMQVENKKMFSVHNGIINALN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPCR_BOVIN
Sequence: MARHVFLTGPPGVGKTTLIQKATEVLKSSGMPVDGFYTEEVRQGGRRIGFDVVTLSGIRGPLSRIGSEPLPGKRECRVGQYVVDLTSFEQLALPVLRNAGASGRPGQSICVIDEVGKMELFSQPFIQAVRQVLSIPGTVVLGTIPVPKGKPLALVEEIRTRKDVKVFSVTKENRNHLLPEIVTHMQSSRK
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  Hydrolyzes nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Cancer-related nucleoside-triphosphatase homolog, NTPase, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: NUP93_XENLA
Sequence: MDGEGFGELLQQAEQLAAETEGVTELPHVERNLQEIQQAGERLRSKTMTRTSQESANVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFVMAEEYHRESMLVEWEQVKQRVLHTLLASGEDALDFTQESETSYISESGAPGRSSLDNVEMAYARQMYMYNEKVVSGHLQPSLVDLCTEAAERLDDKNVSDLWVMVKQMTDVPLIPASDTLKSRCSGQMQMAFVRQALNYLEQSYKNYTLISVFANLQQAQLGGVPGTYNLVRSFLNIRLPTPIPGLQDGEIEGYPVWALIYYCMRCGDLMAAQQVVNRAQHQLGDFKNCFQEYIHNKDRRLSPTTENKLRLHYRRAVRASTDPYKRAVYCIIGRCDVSDNHSEVADKTEDYLWLKLSQVCFEDEANSSPQDRLTLPQFQKQLFEDYGESHFAVNQQPYLYFQVLFLTAQFEAAIAFLFRLERTRCHAVHVALALFELKLLLKSTGQSAQLLSQEPGEPQGVRRLNFIRLLMLYTRKFEPTDPREALQYFYFLRNEKDNQGESMFLRCVSELVIESREFDMLLGKLEKDGSRKPGAIDKFTRDTKTIINKVASVAENKGLFEEAAKLYDLAKNPDKVLELTNKLLSPVVSQISAPQSNRERLKNMALAIAERYKSQGVSAEKSINSTFYLLLDLITFFDEYHAGHIDLSFDVIERLKLVPLSQDSVEERVAAFRNFSDEIRHNLSEILLATMNILFTQYKRLKGSGPTTLGRPQRVQEDKDSVLRSQARALITFAGMIPYRMSGDTNARLVQMEVLMN
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
What are the official names of this protein?
Nuclear pore complex protein Nup93, 93 kDa nucleoporin, An4a, Nucleoporin Nup93.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin interacting component (NIC) family.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.
Protein: IRS4_CANAL
Sequence: MSGNSAANAAALAAFNGIGKKKKESTTKLNGTDNNTNHLGVIGSTSNQTKQHQQQQQQPQALRTPLPAHPSRKKSNKFSQLKRLNTAPAMASLQPALQIASPSISPTQPSAPASALDSDPDYFTLSPHTIPSKNEIAKSPQTPQDMIRNVRQSIELKAIPNNAQAKRLSVDYSPQEMLKNLRHSLHSRTKTSPMLTTSDKMGQTMLAEMRDRLENTRRIASNSVASLSLSPNLDFNKSTSDVSNLSHHYDVDTVSTDSFASFNSSINDRHLPHGISIDVTNHDSDEDEIDDREREEDHEPLDNGELKSTNNKVTVSSRLRRKPPPGEDFQMQLNDKSRDTISSGSYSLNPDEVYSFTDPDSYENLVSEVEVGETTRLFPQFPDANHYHQHSSKFRKKHQKVKPINGIYYRDMDSSNTSDTEESTSNLPSRSTTPLLGQPQQQVHFRSTMRKANTKKDKKSRFNELKPWKNHNDLNYLTDQEKKRYEGIWASNKGNYMSQVVIKLHGVNYETQKDPKEEAKMEHSRTAALLSAAAVEDSNYNGNNSLHNLDSVEINQLICGPVVKRIWKRSRLPSDTLEKIWNLIDFRRDGTLNKNEFLVGMWLVDQCLYGRKLPKKVDNVVWDSLGGIGVNVTVKKKK
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: SLYX_BRUA4
Sequence: MTPDQRLTELEIRVAEQEKTIDELSSVLAEQWKTIDRLSKKLGALTDRFLELEEQTAPDVPVTKPPHW
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: SFSA_SALHS
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: SLU7_KLULA
Sequence: MRRGNSGARGNRGGSRGKPGQNEHIPNFIKNKPWYLAEESEVSASTSAINSNSTISGTGTGTGTELEEKDYLSHHRLKKSSVPDSGTAEIDDAFTYVRPSGRNRKKKDSYDLDLDAPVRRRDEKVIESNYDAKRDRWYGYTPDIKEIERNHKGPDTSHREMDEVQIQEMERLGLKPEDVGFDATQPLSGPKEKYNPVRLREDKAAYLQDMSSEEMLYDPKSRIYKSKEEGTIDPKSKMFHRHLTGDALQVGVINERVRQEAVRSGIKDFEVNKEKLNHVFAANPTKYELMMRTEPERKQETSVEQDAAPKRRKFDKNSFKESSSSSNPGSSTMKDLYDKYM
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_RICFE
Sequence: MNFLDESFWLAVSFIIFVYLIYRPAKKAILNSLDAKILEVQEKVLKAEKLKEDAALLFEQTNAQIQKLETLRSQMIEESNEVTKKIIQEKTKEIEEFLEHKKSDAIQLIQNQKSTATKELQDEFCDEVIKLVSEYFQSAKFSESNIAKNLMDKSDSSHNNDKST
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PGK_PROMT
Sequence: MSKRSLSSLGAEDLCGKRVLVRVDFNVPLGDEGLITDDTRIRAALPTINDLLDKSARVILSAHFGRPKGQVNETMRLTAVAQRLSELLGKTVVKTESCIGAEAKSKVDAMSNGDVVLLENVRFISGEEKNDTEFAKELASLAEVYVNDAFGAAHRAHASTEGVTKFLSPCVAGYLMEKELKYLQGAIDQPQSPLAAIVGGSKVSSKIGVLESLIDKCDKIIVGGGMIFTFYKARGLSVGNSLVEEDKLELASALEKKAQEKGVEFLLPTDVVLADNFSPDANSKLSKVDAISEGWMGLDIGSESVELFQNALKDCKTVIWNGPMGVFEFEKFANGTNAIANTLAELSAQGCCTIIGGGDSVAAVEKAGLAKKMSHISTGGGASLELLEGKVLPGVSALDDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDA_PYRIL
Sequence: MSRQDVQRLLEEYQVINELLATLQAQHTTVSELLEELTTALDGVRLLKTEGGERLVHIGAGLFVLGTFNAREVLTPLGAGYHAFLDLENAERILKERIDEYSKVKTSLEENIEKLIERAAQIRQVLERLGIK
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_STRPM
Sequence: MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFDHIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRLKVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLEDAERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDNLDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFSFGDAMFVN
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_DECAR
Sequence: MTASRLLETINSPADLRRLDRKQLPQLASELRAFLIDSVSKTGGHLSSNLGTVELTIALHAVFNTPEDRLVWDVGHQCYAHKVLTGRREGMSTLRMHGGVSGFPKRAESPYDTFGVGHSSTSISAALGMALAAKHKGEDRKAIAIIGDGAMSAGMAFEAMNNAGVADADMLVILNDNEMSISPPVGALNNILTRLTSSKTYNVAREAGRHMLGFAPPLLELARRAEEHVKGMIAPGTLFEEFGFHYYGPIDGHDLDALIPTLENLKKLKGPKFLHVITKKGQGYKLAENDPILYHGVGKFAACDGIQSAKGPAKLTYTQVFGDWLCDMAKADSRLVGITPAMREGSGMVRFSAEHADRYFDVGIAEQHAVTFAAGLACEGLKPVVAIYSTFLQRGYDQLVHDVALQNLPVIFAVDRGGLVGADGPTHHGTFDLSFVTCIPNMTVMAPADEAECRKMLSTAMTIDGPSMVRYPRGSGTGTIPEAKLDTLPVGKGDIRRRGKDIALLAFGSLVAAAVAAGEELDATVANMRFIKPLDADLIVELAGNHSLLVSIEENAVIGGAGSEIERVLAERGLQVPVLRLGLPDRFIDHGEQGQLLAELGLDKEGIVRAVRARTNPQ
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MRAY_PSEPG
Sequence: MLLLLAEYLQQFHKGFAVFQYLSLRGILGVLTALSLALWLGPWMIRTLQIRQIGQAVRNDGPQSHLSKSGTPTMGGALILSAIAVSTLLWADLSNRYVWVVLIVTLAFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLAAAVFLYKTAPTSVETTLILPFIKDVTIPLGVGFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGSGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGIFVVETLSVVIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNJ6B_XENLA
Sequence: MVEYYDVLGVQRNSSPDDIKKAYRRLALKWHPDKNPDNKEEAERRFKEVAEAYEVLSDSKKRDIYDKYGKEGLAGGGGGGGSHYDVPFQFGFTFRSPDDVFREFFGGRDPFSFDLFAEDPFDDFFGRRGHRGNRSRPGGGSFLSTFGGFPAFGPSFSPFDSGFSSSFGSFGGHGGFTSFSSSSFGGSGMGNVRSVSTSTKIVNGRRVTTKRIVENGQERVEVEEDGQLKSLTINGKEQLLRLDNK
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity.
What are the official names of this protein?
DnaJ homolog subfamily B member 6-B.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus.
Protein: DNAA_TREPS
Sequence: MDAVGYEVFWNETLSQIRSESTEAEFNMWFAHLFFIASFENAIEIAVPSDFFRIQFSQKYQEKLERKFLELSGHPIKLLFAVKKGTPHGNTAPPKHVHTYLEKNSPAEVPSKKSFHPDLNRDYTFENFVSGEETKFSHSAAISVSKNPGTSYNPLLIYGGVGLGKTHLMQAIGHEIYKTTDLNVIYVTAENFGNEFISTLLNKKTQDFKKKYRYTADVLLIDDIHFFENKDGLQEELFYTFNELFEKKKQIIFTCDRPVQELKNLSSRLRSRCSRGLSTDLNMPCFETRCAILIKKIQNYNSTYPHKAIHISDDVVRLVSENISSNIRDLEGALTKIIAFIEVSGSITIDIVPSLLKEFFLSARPKHITVETILHVVADHFNISYSDLKGKKRNKSVVYPRQIAMFLSKELTELSTTELGIEFGGRDHSTVIYGCQKIEGEILTNPSLQANLDLLKSKVQDSIR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_HELPY
Sequence: MFNKVIMVGRLTRNVELKYLPSGSAAATIGLATSRRFKKQDGTLGEEVCFIDARLFGRTAEIANQYLSKGSSVLIEGRLTYESWMDQTGKKNSRHTITADSLQFMDKKSDNPQANAMQDSIMHENSNNAYPANHNAPSQDPFNQAYAQNAYAKENLQAQPSKYQNSVPEINIDEEEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: EFEO_YERPE
Sequence: MSIWFFRRTALHAALLSLPVFAISAQAADIQQVKITVNDKQCEPMALTVPAGKTQFIVHNVSQKGLEWEILKGVMVVEERENIAPGFTQKMTANLEPGEYDMTCGLLSNPKGKLTVTVAAGEQAPVKPDAMALVGPIAEYKVYVTQEVAQLVSQTKAFTDAVKAGDLALARKLYAPTRQHYERIEPIAELFSDLDGSIDAREDDFEQKSADPKFTGFHRLEKILFGDNTTKGADKFADLLYQDTLELQKRIAGLTFAPNKVVGGAAGLIEEVAASKISGEEDRYSRTDLWDFQANVDGAQKIVNLLRPLLEKADKPLLQKIDANFNTVDSVLAKYRTKEGYESYEKLTDADRNAMKGPITALAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL34_FRATH
Sequence: MKRTFQPSNLKRKRTHGFRARMKTLSGRKVIRNRRAKGRAKLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: T23O_DROVI
Sequence: MSCPYAGNGNEHDDGAVPLSNEVGKIYGEYLMLDKLLDAQCMLSMEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRVMLDEEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVKYNQKYSDVFGNDERALHAIRSSEDGPSLLVLVQRWLERTPGLEEEGFNFWSKFQQSVDQFLAAQVQSALLEPVEWAKNYRLMDIEKRREVYRSIFDPAVHEALVKRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRKKLVHKSV
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Protein vermilion, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: EFTS_EXIS2
Sequence: MAITAAMVKELREKTGAGMLDCKKALVEADGDMNAAIDFLREKGIAKAAAKGDRIAAEGLTAVAVNGNKAALVEINSETDFVAKNERFQSLVQNIADAVLRNGSETAEAALASEYEAGKTIDTYISEEASTIGEKISLRRVALFTKEDNAAFGSYLHMGGRIGSVVVVEGTTDETVAKDIAMHIAAARPLYVDRSSVTEEEKAREEKVLTEQALNEGKPANIVEKMIAGRMNKFYEEICLVDQTFVKDPDFKVGKYVESKGGKIVSFVRFEVGEGMEKREENFAEEVMNQLKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS73_YEAST
Sequence: MNRILSSASLLSNVSMPRQNKHKITKALCYAIIVASIGSIQFGYHLSELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYRWRWILFGSFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKIISQLYPQHAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKMNLLIVFSFIYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDVLSGYVFIIFAIIACSISAFIWKKVPETKRSG
What is the function of this protein?
May be involved in vacuolar protein sorting.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 73.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MUTS2_SOLM1
Sequence: MESRTLSLLEFPKVLDRLAGYAASEPAAAACRALGPMGDAARLATEQRKLVEALELRRDRAFEFTAFPDIEPLFAVLESERRVLDLDALVALSHVLSRVAALREALGREEGDSVLGAIVYRTPWAKKTQAALARCLGPDGRLKDESSPELFSVRQEIRSIHQTILTKVKEFISERELGPLLQDDYVTISSDRYVLPLRANFKGRLPGVIHDYSQTGETIYVEPFFLVEINNRLQELKNEEREAEARVMAFLTGLARDERREVAASYRLLVDCDVLWAKAALCDAFGGTLPEVAQGRAVRLLAARHPLLALAGPDSAVAQDLELAPDQRALIVTGANAGGKTVCLKTLGLLAAMALSGLPVPAGEGSSLPFFAKIFVFLGDEQSLEDHLSTFTAQIRHLSRVWPDIDADTLVLLDEFGAGTDPSQGAALAQAVVDGLLDRGAYLAAATHFPALKAYGLSREGVRAACMLFDPATKKPLYRLAYDQVGASIALDVAREHGLPEDILERANRYLLLDGNDTGLVFDRLNDLALRREHELEAIAAKRLAEEGKIQKLKDNLKKAQDKLVEEIRELSRDIVRRHEAGRLGRKEAQKALADVRKRLIDESNELTGGPGGEAAAVAFDLSVVAPGDSVQVTSWNKIGVVREKDLKRQAAKVDIGGVSLWVNVADLAPAAGKPAKAGGGAVVTPTASEAKGLGLVVDLRGMRADVAESELLAFVDNALLRGHGELEVIHGRGTGALRREVHRMLKDHPQVASFAIAPEDRGGDGMTMVTLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: THA11_DANRE
Sequence: MPGFTCCVPGCYNNSHRDRDLRFYTFPKDPTQREIWLKNISRAGVSGCFSTFQPTTGHRVCSVHFPGGRKTYTIRVPTLFPLRGVNERRSRRGRSRKVSAVVPIITSVVSTANETAPLEEDEEEGDIENTTVVQIGQNGQYIAPVDLTSSGDGSCITAVVSGGEESAVHESCSVADFALCGADHSYSLTTGTTSTELLRKLNEQRDIIALMEIKMKEMKNTIRQLRVTEARLQDELRQREQERERLICANTIIKRKL
What is the function of this protein?
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells.  Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
What are the official names of this protein?
THAP domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the THAP11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_FRAP2
Sequence: MSYNFILFVVFIFTLVIITKPLGTYIFKVFNNERTWLDWFAKPFQRVYLLILGESSKKEQSAKSYFFSLLSFSIMAFIFVFVVLLLQGLLPFNPQEIKGMGFSQAFNTAVSFVTNTNWQSYSGETGVSHFSQMLALAVQNFVSAAVGLCVAIVLIRSVARHEATKVGNFWNDLGKAIFWILLPISIIIAIVYIFQGVPQNIMAYLHVHTLAGSDQIIAQGPIASQEAIKSLGTNGGGFFNANSAHPYENPTIITNYIQMVSIFAIAAALTYTFGKWVGNTKQGWMIFAVMLVLFVISLMVMTISELHGLDFLHSKNIQDIYGQVGHLSNMEGKETRFGIFNSTLYNTVSTSASDGGVNSVMDSYSAIGGMMAMLNMAIGEVIFGGIGAGFYGFFMFLMLAVFIGSLMIGRAPSFLGKRIEANDMKWTMFALLISPCCVLVFTGLAAVIPSVHQALTNSGAHGFSEILYAYISGSNNNGSAFAGLAANTSYLNITIALSMLIGRFGVIFAVMMLAGSLVKKKRSSQMSEISSLDTTSFIFSVLVFFTIVLIGGLTIFPALSLGPILDQLNLNF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_AGRRK
Sequence: MVFFPHRHLIGIKGLTEQDITYLLDKADEAVKISRQREKKTSTLRGLTQINLFFEASTRTQASFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMRPDVLVIRHSSAGAAALLAQKVSCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLNAMGARVRVVAPATLLPAGIADMGVEVFHSMKEGLKDADVVMMLRLQRERMSGAFVPSVREYYHFYGLDAETLKAAKEDALVMHPGPMNRGVEIASEVADGPQSVIAEQVEMGVAVRMAVMETLLVSQNQGPRTEGAGA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: G6PI_DESAL
Sequence: MKKTNPVKTRAWLFLEKHYEDIKNRHMRDFFKEDPRRFDNFSLALDDILVDFSKNRITTKTLELLLNLAHEAGLKEMINSMFSGEHINETENRAVLHTALRRQGDEPVLADGKDVMPDVRAVLEQMRVFSGRIITGEWKGFTGKAITDVVNIGIGGSDLGPVMVTECLKPYAKPHMNVHFVSNVDGTHIAETLKLLNPETTLFMIASKTFTTQETMTNAYTARAWFLEKAGDKKHVARHFVALSTNKEAVEEFGIDSQNMFEFWDWVGGRYSLWSAIGLSIACYVGFENFHELLKGAYAMDVHFQKEPFERNIPVILALIGIWYNNFFNAQTEAILPYDQYMHRFPAYFQQGNMESNGKSVDRDGNPVTWQTGPIIWGEPGTNGQHAFYQLIHQGTKMIPADFLAPAQSHNPIGEHHKILLSNFFAQTEALMNGKTAAEVQKELEAAGKLPEEIAEILPHKVFDGNRPTNSILFKKLTPRTLGSLIAMYEHKIFVQGALWNIYSFDQWGVELGKQLAKKILPELEDERPVNSHDASTNGLINAFKHMMG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLTL5_MACFA
Sequence: MRNAIIRCLFYGSLTFGIWTALLFIYLHHNHVSNWQKKSHEPLSAWSPGKKVHQQIIYGSDQIPKPHVIVKRTDEDKAESTLGMDFNHTNPELHNELLKYGFNVIISRSLGIEREVPDTRNKMCLQKHYPARLPTASIVICFHNEEFHALFRTVSSVMNLTPHYFLEEIILVDDMSEVDDLKEKLDYHLETFRGKIKIIRNKKREGLIRARLIGASHASGDVLVILDSHCEVNRVWLEPLLHAIAKDPKMVVRPLIDVIDDRTLEYKPSPVVRGAFDWNLQFKWDNVFSYEMDGPEGPTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMDFWGGENLELSLRIWMCGGQLFIIPCSRVGHISKKQTRKTSAIISATIHNYLRLVHVWLDEYKEQFFLRKPGLKYVTYGNIHERVQLRKRLGCKSFQWYLDNVFPELEASVNRS
What is the function of this protein?
Probable inactive glycosyltransferase required during spermatid development.  May participate in protein loading into the acrosomes and accumulation of ubiquitin-proteasome systems around the head-tail coupling apparatus region (By similarity).
What are the official names of this protein?
Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5, Polypeptide GalNAc transferase 15, GalNAc-T15, pp-GaNTase 15, Protein-UDP acetylgalactosaminyltransferase 15, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type II membrane protein. Note=Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity).