PharMolix/UniProtQA huggingface dataset:
Protein: GPH_NITOC
Sequence: MLKQPEMILIDVDGTLVDSVPDLTFCTDTMMERLGLPLRGETKVRQWVGNGVERLIKRALVDNMEGEPEEDLYQKAETIFLALYADNTSKRSHLYPGVNEGLAWLKSQGYRVGCVTNKAAQFTYPLLTELGIIDYFEIVISGDTLPEKKPHPAPLLHAASHFGIAPEKALMIGDSISDVKAARAANFQIVCLSYGYNHGVDIRDSQPDSVIDSLIEIKNLLSQAA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: LEUC_PAEAT
Sequence: MGKTLAEKVWDAHVVRKGEGEGANAQPDLLFIDLHLIHEVTSPQAFEGLRLAGRPLRRVDLTIATEDHNTPTLDIDKPIADLTSRTQIETLRANCKEFGVRLHSLGDKEQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVMATQTLSLKPFKTMAINVEGTLRPGVTAKDIILAVIAKIGTGGGQGYVLEYRGSAIRALSMDARMTICNMSIEAGARAGMVAPDQTTYDYMQGRPHAPEGADWDAAVEYWNTLTTDADATFDVEVDLDADTLEPFVTWGTNPGQGVSLSAKVPSPEDFGDENAKAAAERALQYMGLEAGTPMKDIRVDTVFLGSCTNSRIEDLRVAADIIRGRAKDPNVRMLVVPGSARVRLEAEAEGLDKVFKEFGAEWRFAGCSMCLGMNPDQLEPGERCASTSNRNFEGRQGKGGRTHLVSPVVAAATAVRGTLSSPSDLEPAAAGALTGIAV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y4420_PSESM
Sequence: MIPRSTRQQAGREAEAFALQFLQQQGLRLIEQNWLCKRGELDLVMLDGDTVVFVEVRYRRHCGWGGAVESVDFRKQGKLVTAAQLFLQQVSCWADYPCRFDVIAIEGSPGSFDGSTVPLNWIKSAFDS
What are the official names of this protein?
UPF0102 protein PSPTO_4420.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HISX_DEHMC
Sequence: MKIIRGFAQAEKRLSRRDKAGFFLDETERTELARRLGVDPEKAVNGIIADVRKQGDEAVLGYTLKFDRANLSKLEVGQPEIQQAASEIPAELFEALQLAASQIRAYHRFQKEAVWKTAEIMQGKQLIRPLERVGLYVPGGKAFYPSTVLMTAIPAREAGVKEIILVTPPGANGKIPAPTLAAAQIAGVDRIFACGGAQAVAALAFGTKSIPKVDKICGPGNIFVTLAKKAVFGVVDIDGLQGPSEVLIVADQYANAEYCASDILAQAEHDALASSILITTSEDLANRVNDIVESKADTCSRRDIIKQSLRDNGLIAVVDNINEAIKLANMYAAEHLCLLVKDSEKYLTQINHAGCIFYGEKASVVMGDYVAGPSHALPTSGTARFSSPLNILDFVKYIDIVKVDKQDIAKLGQAAATIAKAEGLECHAEAVLKRLE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: Y551_BACCR
Sequence: MGEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFRELELPNLKRKEMDENRIEHVEFNDIRKTGLWGNIDKKRTMISAYKRNAMGGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVTEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFREESGEKMA
What are the official names of this protein?
UPF0229 protein BC_0551.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: ECFA2_HALH5
Sequence: MKGSPFEKVALSDVSFTIPSGSFTAIIGHTGSGKSTLAQHFNGLLRPSKGTVRLGELEITADQKPPSLKEIRRKVGLVFQYPEHQLFEETVEKDICFGPMNYGVSEARAKKRAKELLHLVGLPDTYLQASPFSLSGGQMRRVAIAGVLAMEPDVLVLDEPTAGLDPEGQRLIMDMFYRLHQEKELTTVLVTHNMSDAAKFADQIIVMSQGNVAMTGDRQTVFARADELVALGLDVPETLQLLLQVKERFGLHDVPPLFSLEELADFLAKELQQKEGQPCSKI
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
Protein: HIS4_HALHL
Sequence: MIVIPAIDLKNGHCVRLRQGRMDDETIFDADPVAVAGRWVEAGAERLHLVDLDGAVRGEPAHEQTIHAIARAYPDTPLQIGGGIRSRETALRYLEAGVGYVIVGTRAVREPAFVEELCREIPGRVCVGLDARGGYVATDGWEQTSEVAAVDLARRFEDAGVAALIFTDIGRDGMMQGCNVEATRELARAVSIPVIASGGVSSLEDVRSLAGSPEGIAGAIVGRAIYDGGLDLATAIRTAQEVGDDR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTS1_GIBZE
Sequence: MSGNHVIGNRNSTPEANNTSTLRPPSSRAIGSGHSLRASADMASLTGPSPSNRIRPSSDFYGQAQQNLGPNNAESDSQDKIAQQWIADIDQYETTLEEMAAATLDQDFKDELSAIEQWFRVLSEAERTAALYALLQQTTQVQIRFFIQVLQQMGKNHPLSGVLSPASFDKDPMSNRLSDAMNKLNVDSARNSMARSSVIAPSTKRHSGLDPTTISAMFPDAAAAIATEKAKFTQQTGNPPSSNRNSIALDHRSSMAAPSISAPQDGRDAGPAGSSPWNSGGNGDTSAKPSSSQTPMGQFVQPTPSGGLRSPRPQLSSNNTIQQTTLNAPDKTPADLPLLSPYNAGSGNWASMVNTPMTSTFNAAATGGNQADMVANATAMKLAALSTVNNRFALDDVRKYRRARSNDGTPGQNPVPTGPQPGINMPNANVVMINEHGQVLSREQIMALQAQQSLGMGGQRSRPSSPGLAMQPGLAHMAPFTSPQNNGFLSAYDVSSPLLSAGMQSVNMGSLGMGGHEGYLSDHSDMVRGRSPRGRRGSSKPPEDPTDPTLLQDIPSWLRSLRLHKYTDNLKDMKWTDLIELDDKALEERGVNALGARRKMLKVFEQVKEAKADGKLG
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
What are the official names of this protein?
RNA-binding protein VTS1.
What is the protein family that this protein belongs to?
Belongs to the VTS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body.
Protein: ANX1_ARATH
Sequence: MSGKTRILFFLTCLSFLLVFPTRSNGQDLALSCGTSEASADQDKKKWEPDTKFLKTGNSIHATATYQDPSLLSTVPYMTARIFTAPATYEIPIKGDKRHLLRLYFYPSTYTGLNISNSYFTVEANDVTLLSNFSAAITCQALTQAYLVKEYSLAPTDKDVLSIKFTPSDKYRDAFAFINGIEVIQMPELFDTAALVGFTDQTMDAKTANLQSMFRLNVGGQDIPGSQDSGGLTRTWYNDAPYIFSAGLGVTLQASNNFRINYQNMPVSIAPADIYKTARSQGPNGDINLKSNLTWMFQIDKNFTYILRLHFCEFQLSKINQKVFNIYINNRTAQADTTPADIIGWTGEKGIPMYKDYAIYVDANNGGEEITLQMTPSTFGQPEYYDSSLNGLEIFKMDTMKNLAGPNPEPSPMQAEEEVKKEFKNEKRHAFIIGSAGGVLAVLIGALCFTAYKKKQGYQGGDSHTSSWLPIYGNSTTSGTKSTISGKSNNGSHLSNLAAGLCRRFSLPEIKHGTQNFDDSNVIGVGGFGKVYKGVIDGTTKVAVKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGTLREHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEILCARPALNPSLPKEQVSLGDWAMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCLNDSGLERPTMGDVLWNLEFALQLQETADGTRHRTPNNGGSSEDLGRGGMAVNVAGRDDVSDLSSEDNTEIFSQIVNPKGR
What is the function of this protein?
Receptor-like protein kinase that controls pollen tube behavior by directing rupture at proper timing to release the sperm cell.
What are the official names of this protein?
Receptor-like protein kinase ANXUR1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRPA_ECODH
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PSAK_THEVB
Sequence: MVLATLPDTTWTPSVGLVVILCNLFAIALGRYAIQSRGKGPGLPIALPALFEGFGLPELLATTSFGHLLAAGVVSGLQYAGAL
What are the official names of this protein?
Photosystem I reaction center subunit PsaK, Light-harvesting 8.0 kDa polypeptide, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: MRAY_DICTD
Sequence: MNIILFTSLVAFFVFLLILKYWINFQKSKGIGKYIRKEGPSSHFQKSGTPVMGGIIFLIVSIPFLFFKETFFPSLSTILFGLLGLLDDFKLMVNKDYGIRPLRKIFLSFIITLLLYIFSFHDYKIYWGSKLIISSRIFYVILFFVVFIAVPNAINLTDGLDGLAGGTSLITLFFFLIYNFQFNNELTLEISLMITALIAFLWFNSHPAEIFMGDVGAFALGGFIASLSIINKVELLLVFLGGIFLIESLSVFIQVFFYKWKKRRVFLMSPLHHHFELKGWKETKVVWRFYIIHLIMMIGGIILWNLT
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_PELUB
Sequence: MIKIRLSRGGTKKRPVYKVVIADSRRARDGRFIEKVGFFNPLLPKDKKERVGLEAERIKYWLGQGAQPTTRVARILGENGIIAMPANGSNPSKAIPKKERKKEGDEAAPAAAPKAEAAPAAEAPKEEAPKAEAAPAAEAPKEEAPKAEAAPAAEAPKEEAPKAEAAPAAEAPKEEAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: THIC_BACAA
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIIKSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ODFP4_HUMAN
Sequence: MDAEYSGNEFPRSEGERDQHQRPGKERKSGEAGWGTGELGQDGRLLSSTLSLSSNRSLGQRQNSPLPFQWRITHSFRWMAQVLASELSLVAFILLLVVAFSKKWLDLSRSLFYQRWPVDVSNRIHTSAHVMSMGLLHFYKSRSCSDLENGKVTFIFSTLMLFPINIWIFELERNVSIPIGWSYFIGWLVLILYFTCAILCYFNHKSFWSLILSHPSGAVSCSSSFGSVEESPRAQTITDTPITQEGVLDPEQKDTHV
What is the function of this protein?
Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.
What are the official names of this protein?
Outer dense fiber protein 4, Outer dense fiber of sperm tails protein 4, Testis-specific protein oppo 1, hOPPO1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTI_POLSJ
Sequence: MTTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSALPRFDGGGALVTPGLVDCHTHLVYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAAGEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQLRVARRLGEAYGVTVRTTFLGAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQRLGLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTLRDTHLPPIAALREAGVPMAVSTDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHAARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQAPRTIVRQGRVALDGLQIAPNARITP
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSV3_CAEEL
Sequence: MSDAAAPAQAPAPPTHAPLTPHKHCNTRDRLFGQDPPAVASPKRVTPTFKSQIFDDVPASPSRTPKRTVQVVSRNPVTGEIKPSPSQQQVAA
What are the official names of this protein?
Uncharacterized protein T19C3.3.
Protein: Y4512_PSESM
Sequence: MAEASIQIEVVYATVQRQVLMTVDVPAGSSVRQALALCGMDREFPELDLSHCPVGIFGKVVADPAARVLEAGERIEIYRPLLADPMEIRRLRAAKAREKRTLPG
What are the official names of this protein?
UPF0125 protein PSPTO_4512.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: METK_AERPE
Sequence: MARRIVVESYPYPRVEDLQVELVERKGLGHPDTICDAAAEAVSRELSKYYLERFGKILHHNVDKVLLVGGQAAPRLGGGEVLQPIYILVSGRVTTEVRTGGGVESVPVGPIILRAVKNYIRENFRFLDPEEHVIVDYRVGRGSVDLVGIFEAEDKVPLANDTSIGSGHAPLSTLERLVLETERILNSRETKERLPAVGEDVKVMGVRDGKSITLTVAMAVVSSQVGSVSDYLAVKEEAESLILDLASRIAPDYDVRVNINTGDIPEKKILYLTVTGTSAEHGDDGATGRGNRVNGLITPMRPMSMEAAAGKNPVNHVGKIYNVVANEMAALIHREVKGVEEVYVKLVSQIGKPIDRPRIVDVKVRMEGGREVTADAKREIEAIANSVLDGITGYTEKLVRGDITVY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: RL3_COLP3
Sequence: MTIGLVGRKVGMTRVFTEDGVSTPVTVIEVEANRVAQVKTVDNDGYSALQVTTGKRKASRVTKPAAGHFAKAGIEAGRGLWEFRLNENEGSDIEAGSEITVEVFNDTKLVDVTGTSKGKGFQGGIKRWNFTMQHATHGVSLSHRSNGSLGQCQTPGRVFKGKKMSGHMGAVRCTTQNLELVRVDAERNLLLIKGAVPGAINGNVIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MAZF_STAEP
Sequence: MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITDGINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTFLSESKMIEVDNALDISLGLNNFDHHKS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis.  It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA.  Neutralized by coexpression with cognate antitoxin MazE.
What are the official names of this protein?
Endoribonuclease MazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: REXO3_YEAST
Sequence: MGSLLRPVDLVNQPLGFQERYKILQKLFKQLQKAYAHTKGTNIDLERLATRLEVHVAKNSLSGQSYKFNMSILLRDVLKYKGDLSKIKINGRPLKGAKPHLSSIGNANSITTKSKAMEALKALILDSKVLEKNGYIVKEMQNKTNDDNSTQLYAPCLRCSSNFKKTDIMEKTLCRYHPLKRIYNRDTKNHQYPCCGETTDSVSFLRLGCKTFFHHVFRGESYDELCKISKFSSTDDIDGVENVLSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDHVIQPIGDIVDLNSDFSGVHEIDRTNCPTYKEALDVFLSENLINKNSILIGHGLENDLNVMRLFHNKVIDTAILYSRTKFKVSLKNLAFEVLSRKIQNGEHDSSQDAIATMDVVKVKIGISPSQNKWEK
What is the function of this protein?
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
What are the official names of this protein?
RNA exonuclease 3.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BCDO2_HUMAN
Sequence: MFFRVFLHFIRSHSATAVDFLPVMVHRLPVFKRYMGNTPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNVFERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDLDGTAYNMGNSFGPYGFSYKVIRVPPEKVDLGETIHGVQVICSIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTRFHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKAGEGLDQVHNSAAKSFPRRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHENLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFRHLVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFILVLDAKNFEELGRAEVPVQMPYGFHGTFIPI
What is the function of this protein?
Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids.  Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond.  Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
What are the official names of this protein?
Carotenoid-cleaving dioxygenase, mitochondrial, B-diox-II, Beta,beta-carotene 9',10'-oxygenase, Beta-carotene dioxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS19_GLUOX
Sequence: MARSVWKGPFVDGYLFGKAEASRASGRNEVIKIWSRRSTILPQFVGLTFGVYNGHKFLPVQVTENMVGHKFGEFSPTRTYTGHGSDKKSKRG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: H33B_LILLO
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSIPTGMGGMKRPRRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDYKTDLRFQSHAVLALQEGAEAYLVGIFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3b, Histone soH3-1, Somatic-like histone H3-1.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CU198_LOCMI
Sequence: IYVPAPAPAVYAPYAARAYAAPAVVAAPAAPAVRAAAVPVAAAAPAAVAAAEYDPHPQYSYGYSVNDALTGDSKSQQESRDGDVVQGSYSLVEPDGSVRTVDYTADPVNGFNAVVHKEPGVHAPIAAPVPAPAVPAGHVRTTVAAPAVAAAPVVRAAIAAPAYATYAAAPIARTAVAAPAIAAAPIARAAYAYPYAGAYF
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 19.8, LmNCP19.8.
Protein: HXB13_MOUSE
Sequence: MEPGNYATLDGAKDIEGLLGAGGGRNLVSHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTAALATYPSETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds preferentially to methylated DNA (By similarity).
What are the official names of this protein?
Homeobox protein Hox-B13.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HNF4_DROME
Sequence: MMKHPQDLSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEYNRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY
What is the function of this protein?
Transcriptionally controlled transcription factor.  Important for the differentiation of various specialized cell types that arise from both endoderm and mesoderm.  May have a role in early gut formation.  Plays an essential role in lipid catabolism, regulating lipid mobilization and beta-oxidation in response to nutrient deprivation.
What are the official names of this protein?
Transcription factor HNF-4 homolog, dHNF4, Nuclear receptor subfamily 2 group A member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Protein: PAND_THEM4
Sequence: MQEILLKSKIHMAKVTDKSINYMGSIGIDVELLEKSNIKPYELVLVADVNNGQRFVTYTIPEEKGSRKIVVNGAAARLVEQGDRVIIMAFGMYENDEYKGPRVLIMNEDNEVVEIREGT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSN1_DANRE
Sequence: MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVVAMAPTAQAEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI
What is the function of this protein?
Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10521267).  Requires the presence of the other members of the gamma-secretase complex for protease activity.  Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity).
What are the official names of this protein?
Presenilin-1, PS-1, Zf-PS1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic granule. Cell membrane. Cell projection, axon. Synapse. Cell projection, neuron projection.