PharMolix/UniProtQA huggingface dataset:
Protein: SYH_COXB2
Sequence: MTKSIQAIRGMSDTLPEEIPYWSFLENACRSVVSAYHYREIRFPVVEQTALFKRTIGEATDIVEKEMYTFTDRNGDSLTLRPEGTAGCVRAGIQNGLFYNQIQRLWYLGPMFRHERPQKGRYRQFYQLGVETYGMAGAPIEAELIFMCLRLWKALGLESCIHLELNTLGTLDSRNAYRQALVTYLQSREKELDEDSRRRLHTNPLRILDSKNPDLQPLLAEAPKLIDYLDETSRRHFDQLRSLLDQAEVPFIVNPTLVRGLDYYTHTVFEWVTDQLGAQGTVCAGGRYDNLVELLGGKSTPAAGFAAGLERLVLLLRGVQECLDKIDIYVVIAGEAVIQEGLLMTEQLRNVLPEWVIEADLSGSSLKSQFKRADKSGAKWALVIGEEEIKTNTVTLKHLRETVPQKNLTRDTLISYLKSEG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELBH_ECOH1
Sequence: MNKVKCYVLFTALLSSLCAYGAPQSITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGATFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMEN
What is the function of this protein?
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
What are the official names of this protein?
Heat-labile enterotoxin B chain, LT-B, human, LTH-B.
Protein: PYRD_CERS1
Sequence: MNILERAALTALHRMDPEKAHSLSLSALRSGLVPLPGPVTSPRLATDVGGLVLPNPVGLAAGYDKNAVALAALMRAGFGFLEVGAATPRPQPGNPQPRLFRLTEDRAAINRFGFNNDGAATICARLAMRPRGAVPVGLNLGANKDSPDRAADFAAVLAACGPHADFATVNVSSPNTERLRDLQGRQALTALLEGVMQVQAGFARPVPVFLKIAPDLSDADLAEIAEVALASGIAGIVATNTTLARDGLRSAHARETGGLSGAPLFERSTRVLARLSELTEGRLPLIGVGGVASAEEAYAKIRAGASAVQLYTAMVYQGIGLAARIARGLDALLLRDGFGSVAEAVGTGRADWLT
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SGRR_YERPA
Sequence: MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLPWLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQHCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA
What is the function of this protein?
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ.  Represses its own transcription under both stress and non-stress conditions.  Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
What are the official names of this protein?
HTH-type transcriptional regulator SgrR.
Protein: ISPF_SYNS3
Sequence: MTSSVPSLRIGNGYDVHRLVPDRPLILGGQLLEHPAGLGLDGHSDADVLVHAIMDALLGALSLGDIGKYFPPSDPQWKGADSLVLLEQVVALVKARGWGVVNVDAVLIAERPKLKPHIEAMRSAIALRIGVAPDQVGVKATTNEQLGPEGREEGISCQAVALLQAL
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: GUAA_YERP3
Sequence: MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFNPSGIILSGSPESTIENGSPRAPDYVFTAGVPVLGVCYGMQTMAIQLGGKVESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVWMSHGDKVAEIPADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLGICGCEALWTSATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDKFGLNIVHVAAEDRFLSALAGVDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TTDA_METJA
Sequence: MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLCQDTGVPIVFLKIGKNINSSEIMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGLNSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPSDGIEGIKNFVLETIANAGGKPCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGLGGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL
What are the official names of this protein?
Putative L(+)-tartrate dehydratase subunit alpha, L-TTD alpha.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: MDHC1_ARATH
Sequence: MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS
What is the function of this protein?
Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organellar compartments.
What are the official names of this protein?
Malate dehydrogenase 1, cytoplasmic, Cytosolic NAD-dependent malate dehydrogenase 1, cNAD-MDH1, Cytosolic malate dehydrogenase 1, Cytosolic MDH1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_NYCCO
Sequence: MTNIRKNHPLMKIINHSFIDLPAPSNISSWWNFGSLLGLCLTIQIVTGLFLAMHYTSDTSTAFSSVAHICRDVNYGWIIRYIHANGASMFFFCLFIHIGRGLYYGSFTLLDTWNIGIMLLIAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWVWGGFSVDKATLTRFFAFHFILPFIVAALVVIHLIFLHETGSNNPSGISSDSDKIPFHPYYSLKDLLGVVFLLATLSILVLFSPDLLGDPDNYTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAMSILILALIPHLHTAKQRSMMFRPLSQCLFWVLVANLLTLTWIGGQPVENPFIIIGQTASILYFLTILILMPLTSLFENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACYP_RHOPB
Sequence: MSTIVRQVTVQGRVQGVGYRAFVEYQAMKLDLEGWVRNRRDGSVEALFAGPAEAVAEIIARCRRGPSSARVTKLDEQPGSVDALDLRRPGERFSTLPTL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RT09_DEBHA
Sequence: MSVRSLYGISGLRISTRTFSKTAFRLQEQVNQTQESTDTEINGRPLVPANLKNAKGERLMIPSKLQENALRNYELERLRIIPKLNTFYGGNPVHEENLNTLNGLIRKYINLPTRIVDDKEIQNTKFVSFEEYKTRIQSGTRLKPIHHKELTQLLHRLRSIDPELMPREVSDVLAKFANTSSESAKAAQKVKTLDEFGRAISLGKRKRSVAKVYLTKGDGQVMVNGKSLLEYFPKEADRRRIAYPFQVVSQEGQYNVFAEVQSGGSTGQAEAVMYGIAKDLVIFNPLLKSRLHKSGLMTRDARKVERKKPGKVKARKSPTWVKR
What are the official names of this protein?
37S ribosomal protein S9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS6_KLEP7
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGAITAAAGTIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEAIDELETNFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERREDFANETADDSEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: AT1B2_MOUSE
Sequence: MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFSLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNISDTESWGQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGDCSGIGDPTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCVGKRDEDAENLGHFVMFPANGSIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
What is the function of this protein?
Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-2, Adhesion molecule in glia, AMOG, Sodium/potassium-dependent ATPase subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: Y085_MYCTO
Sequence: MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQGAALAAIPLLRGIRDNDRALIAVGIAVLALRALVLPWLLARAVGAEAAAQREATPLVNTASSLLITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLHAVSQAAGFLMLDNGIAATAFLLTAGVPLIVELGASLDVLFAVIVIGVLTGRLRRIFGDADLDKLRELRD
What are the official names of this protein?
Uncharacterized protein MT0092.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOAC_SHISS
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIVGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: LEPA_RICRO
Sequence: MNHQKYIRNFSIIAHIDHGKSTLADRLIEHCGGLQAREMSQQVLDSMDIEKERGITIKAQTVRLVYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLANVYQAIENDHEIVLVLNKLDLPASEPEQVKQQIEDIIGIDTSEAVLISAKSGIGIDLVLEAIVSKLPPPKESSSDILKALLVDSWYDPYLGVVILVRVIDGYLRKNMRIKMMATNSVYTVENVGYFTPKKHISDVLHAGEIGFFTAAIKQVADCKVGDTITDEKKPCEQALPGFKPQLPVVFCGLYPTDSSEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFNLDLITTAPSVVYKIHMRDGENLEIHNPADLPDLQKIESMEEPWIKATIMVPDEFLGAVLSLCTEKRGMQLDHSYIANRAKIIYKLPLNEIVYDFYDRLKSCSKGYASFEWQMDVYEPSELVKLGILVNAEVVDALSTIVHRSRAEQRGRALCVRLKDLIPRQQIDIAIQASIGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKRMRQYGNIEIPQSAFIAALKIGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNLJ_CLOK1
Sequence: MDIKKRIDELRKIIEYHNDKYYNQDDPEITDYEYDKLYVELRNLENSHPEYKIQSSPTQKVGGTVKRELRKVKHDIPVVSLQDVFSKEEVYSFVEKITSEVTYPKFVVEKKIDGLTVVLRYYNGELKEAITRGDGSIGESVFENILQVKSIPKHIPSKLNYLEIRGEIYMTNENFIKVNEKQEEIGGKIFKNPRNLAAGTIRQLDTSIVKDRNLDIFIFNLEISEGKKFETHSETLEWLSNQGFDVSPNFKICETADEVWNAILDIEESRWDLGYSIDGAVVKVDNLNDRISLGMTSKVPKWTVAFKYPPEQKETVIEDIIVQVSRTGRLNPLALLRPVILANTTISKATLHNQDFIDSKDIRIGDTVIIQKAGDIIPEIIRSIPEKRPDWAKKYIIPDVCPVCNSKTIREPDGVDTRCSNPDCEAQSFRKIGYFVSKDAMNIVGFGQNTVEALMKDGYIKKISDIYILKNYKDALIEKGIIGKEKSVNNLLNAIELSKDNDIDRLITGLGIRNVGKQSAKILAGNFKSMDELAGAAYEQLIELEDFGPTTVPDILEFFNSNAYIELIKKLKEAGVNTISKTLQKKIDNRFLGKTFVITGTLPTMKRDEAAEIIQSFGGKVSGSVSKRTSFVLAGEEAGSKLTKAQQLGISIITEEDLKDMIK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: G3PT_MESAU
Sequence: DRCPCPCPCPCPCPVIRPPPPKELTVGINGFGRVVAVNDPFIDPEYMVYMFKYDSTHGRRVVVTAPSPDAPMFVMGVNEKGKLTGMAFRVVDLLRYMFSR
What is the function of this protein?
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon.  Required for sperm motility and male fertility (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, Spermatogenic glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAZA2_NEONE
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: MNME_WOLTR
Sequence: MMNTDETIFALSTVFGKSGVAVIRISGNHALKALNHFHVNKDMKPRFATLVDLYDSSDQLIDNGIAIYFPAPNSFTGEDVIELQVHGGKAVIKIVLEELSRIFVMAKPGEFLLRAFLNGKFDLTQIEGIADLIDAETKMQAKQAIKQMSGELEKLYSSWRQRLIAVQSKIEAYIDFPEDVATEKNELEKINDEVQTLVQSIQEHLNDNRRGERLREGLHIVITGEPNVGKSTLFNFLARRDIAIVSEYVGTTRDILEAHIDIGGYPIILSDTAGIRESSDPVESEGISRAKKRSCEADLRIELFPFEQRYNINCNVISSNTIYVLSKADDVINDHDIKISDIDFLPVSILKGIGTEKLVSVIKEKVEEKFVYDRDVPVITRQRHRNCMQKAIEHLRRFNMNNPIELVSEDLRLAASELGVVTGIINVEEVLDDIFNNFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEP14_HUMAN
Sequence: MAERTMAMPTQIPADGDTQKENNIRCLTTIGHFGFECLPNQLVSRSIRQGFTFNILCVGETGIGKSTLIDTLFNTNLKDNKSSHFYSNVGLQIQTYELQESNVQLKLTVVETVGYGDQIDKEASYQPIVDYIDAQFEAYLQEELKIKRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTMKNLDSKVNIIPLIAKADTISKNDLQTFKNKIMSELISNGIQIYQLPTDEETAAQANSSVSGLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHRKK
What is the function of this protein?
Filament-forming cytoskeletal GTPase (Probable).  Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity).  Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments (PubMed:33228246).
What are the official names of this protein?
Septin-14.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Perikaryon. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Colocalizes with actin stress fibers (PubMed:17922164). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity).
Protein: RNPH_CUTAK
Sequence: MSETSRIDGRRLDQLRDVRIERGWLSQAEGSVLVSFGRTTVLCNASVTEGVPRWRKGSGLGWVTAEYEMLPRATNERSGRESRKGKVGGRTHEISRLVGRSLRAVVDDKALGENTIILDCDVLQADGGTRTASITGAYVALIDAVNWLRGRGGLVSEPIIGSVQAISVGVVDGIPMLDLAYKEDSRADTDMNVVMSGNGDFVEIQGTAEGTPFNRNLLNELLDLAAGGCATLKQAQSEALGVTL
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ASR_ECOSE
Sequence: MKKVLGLVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAGKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATR10_STAC4
Sequence: MARQSAEPPTDDGQSAKEIVVITGGNTGIGFEVARQLLCNYGNRFYVIIGSRTLGKGHTAVAALKQQGYEAVQAVQLDVTKEASIAAAAKIIGEQFGRIDVLHVNAGVLLEPTDINAKPVPFSETIMETMRTNVAGAAATVEGFTPLLSIGSNPRVVFMTSTAASAQLMHQYSSMTTAPALSASKAAENIIMIYYYHKYPNWKVNACYPGYRDTAMMRRYNASSLSKAYRQPDPVEEGAYNAVRLSLLGKDGETGTFTEYKGVGEDGQRQYSALPW
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the core atranone cluster (CAC) which products are predicted to catalyze most or all steps of mycotoxin atranone synthesis, starting from geranylgeranyl pyrophosphate (GGPP) (PubMed:25015739).  The initial cyclization of GGPP to dolabellane is probably performed by the terpene cyclase ATR13 (PubMed:25015739).  The Baeyer-Villiger oxidation near the end of the atranone synthesis, which converts atranones D and E to atranones F and G is predicted to be catalyzed by the monooxygenase ATR8 (PubMed:25015739).  Of the CAC's other predicted gene products, the reducing PKS ATR6 might synthesize a polyketide chain (PubMed:25015739).  This polyketide is probably transferred onto the atranone backbone by the polyketide transferase ATR5 (By similarity).  Other predicted CAC products include 4 oxygenases (ATR2, ATR3, ATR4, and ATR14), 3 short-chain reductases (ATR7, ATR9, and ATR10), and a methyltransferase (ATR12) (PubMed:25015739).  These may all be involved in the various steps of atranone biosynthesis, although their specific roles must await experimental determination (PubMed:25015739).
What are the official names of this protein?
Short-chain dehydrogenase/reductase ATR10, Core atranone cluster (CAC) protein 10.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYH_SULAC
Sequence: MSEFEPIRGMKDYYGEELNKIKFIEETFRTVVLNSGYQEVYTPIVEDFKLFSLKSGEEIRKTMYVFKDKADREVALRPEITPSIVRVYLNSMQHLPKPLRLFYVGQVYRYDEPQFGRYREFRQAGVELLGSSSSFADIEVISLLNEIYDSLGLKDKIIIKINNIGIYREIFNKAGITEEQQEHLLHLIDKGKVDDALKEFTDNNYKDLITYLISLKFDKLESDKLESLRREVSKYNFNLEGEINKLSFISEVLEDLGVKIKIDLGFVRGLAYYTGVIFEVIHPDVSFSIAGGGRYDNLVRLYGGADTPAIGFAIGVERTALVINKIKSDLQRKKIAVIPLISTKDSLSLAIRLLNILRKNNIIGVLNLKDVPLSKLMTYYVEEGYNAIVLIGKKELEENSITIKFLEKREQKTVKLEKIEDVLINNLS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_GEODF
Sequence: MIYGTGVDIVDISRFQRFVSENNTSLLQRVFTPRELEYCSGKKHSAQHFALRFAAKEAFLKALGTGLRGGVSWQHMEIVNDRLGKPEMLLTGKAGELFAEAGLQKIFLSLSHDGNMAVAMLVLEK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_STRPF
Sequence: MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_YERPA
Sequence: MTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDFAWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQVKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVTGHDDLAVLNKNLPKEWLLSLGVINGRNVWRADLSSWFERLQPLVNSRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIERQLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKHAIAEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAAQRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQV
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.