PharMolix/UniProtQA huggingface dataset:
Protein: RGYR_THEMA
Sequence: MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLPEDSPSDIYRALLERKTLKEYRFYHEFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTTFGMMTALWLARKGKKSALVFPTVTLVKQTLERLQKLADEKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISSRSKEKLVELLEIFRDGILIFAQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGVDLPERIKYVIFWGTPSMRFSLELDKAPRFVLARVLKEMGLIKAQENPDVEELRKIAKEHLTQKEFVEKVKEMFRGVVVKDEDLELIIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEEAEANWKELVHEVEESRRRSERELTDTSRSLLIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEENGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPSTRSLRRIEMHEITRYGFKKARESVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQEAEEEKNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLRKIGKEDIFMGRSWSTEGAHEAIRPVKPIDARELEEMIEEGLIADLTKKHLRVYELIFNRFLASQSAAVKVKKQIVTVDVDGKRMGIEQIVEILRDGWNLFVPLTVSPRFEHRTYKIKEKKFYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEEG
What is the function of this protein?
Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process.  It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue.  May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
What are the official names of this protein?
Reverse gyrase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
Protein: ATPF_COXB1
Sequence: MDINASLIVQMLVFVVFIGLTMKFIWPPLTKALEARRKNIADGLAAAEEGRKELELAEIKSKEQLTEAKTQAAHIIEQANQRANHIVEEAKNKAREEGAHLIQLAKNEIEQEYNAAKTELLKQISTIAVAGAQKILQREVDKASNDRLVDELVSEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RLMG_SHIDS
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CHLVU
Sequence: MMKTHNLFVSCIESRVQDQGSLYARFHIGTFFRGQALTFGNSIRRALLSEMPGFLMTDVRIQGATHEFAVLPDVEETVLEILLNLKKTVFVPRIPKNQKFETFQGFGFLKNNGPGKVRAADIRLPETVQCVSPEVHIATLTSGAELSLRFNLQFRNFSQLEKREGTFKSKTVAQAKTEDGNVQDTTNELPTLEKNSLFFQQLQNKRNSKDQLFLDTVPMPVQKVNYVIKSLNAKNGSEYIILEIWTDGSLYPQESVEFALRNLTDLFFQFANISKKSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PB2_I80A6
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGIAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HSP1_DASBY
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHRNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DAPB_CERS4
Sequence: MSDLPGIVVTGASGRMGQMLMKTVLASGKARLVGAVERPGSDWVGRDAGAAMGGAAVGVTVTDDPLAAFAQAQAVIDFTAPEATVQFAELAAQARAVHVIGTTGLEPAHLERLAWAAHHAVIVRAGNMSLGVNLLTRLTQKVAEALDEDWDIEVVEAHHRMKVDAPSGTALMLGEAAARGRGVDLAQARVSGRDGITGPRAPGSIGFSAIRGGDIVGEHDVIFAAAGERITLRHVATDRAIFARGALKAALWGQDRRPGQYDMMDVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_COREF
Sequence: MRPTPDLRCYFITGHGSHEHIVDVARRAVAGGARTVQVRSKPITARELYALTEAVALAVGETAHVLVDDRVDIALALRHRGLPVHGVHVGQDDLPVRDVRALLGEEAIIGLTTGTRELVEAANEHAEVLDYIGAGPFRPTPTKDSGRPPLGVEGYRELVELSRLPVVAIGDVTADDAPALADTGVAGLAVVRGLMESADPTGYARRLITGFGEGRQ
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL10_SHESR
Sequence: MALRLEDKKAIVAEVNEAAKGALSAVAADSRGVTVGAMTGLRKKAREAGVYVRVVRNTLARRAVEGTAFECLAETFTGPTLIAFSNEHPGAAARLLKDFAKEQANFEVKGAAFEGNFIPAADIDRLAKLPTYEEALAQLMMTMKEASAGKFVRTLAALRDQKQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CYSD_SHEB2
Sequence: MAGRELSHLQQLEAESIQIIREVAAEFDNPVMLYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTGWKFKEMIAFRDAQAKKFGFELLTHINPEGLAQGINPFDHGSAKHTDIMKTQGLKQALNQYGFDAAFGGARRDEEKSRAKERVYSFRDRHHRWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIELVPLYFAAKRQVVERGGQLIMADDERMKLAEGEQFKEELVRFRTLGCYPLTAAMHSEADSLEKIIEEMLLTRSSERQGRLIDSDQSASMEQKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: UNGI_ARATH
Sequence: MALSTPKTLMDFFQPAKRLKASPSSSSSFPAVSVAGRSRDLGSVANSPPRVTVTTAVADDSSGLTPEQVARAEFHKFVAKSKSNLAVCSVKVTKAKGLILIMDLVKLWVYPSMCLKEKSPSSLLNIFKELHKDVGDKLHMVYFRRNKKENVSHVTSLAVEDVTGITRTKG
What is the function of this protein?
Probable inactive paralog of AtUNG (AC Q9LIH6) generated by a gene duplication event and subsequently disrupted by at least two transposon insertions.
What are the official names of this protein?
Probable inactive uracil-DNA glycosylase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PT148_ARATH
Sequence: MAKMINKTLVLTYIYLLIYIILSSGVILYNKWVLSPKYFNFPLPITLTMIHMGFSGFVAFLLIRVFKVVSPVKMTFEIYVTCVVPISAFFASSLWFGNTAYLHISVAFIQMLKALMPVATFLMAVVCGTDKARCDVFMNMVLVSVGVVVSSYGEINFNVIGTVYQVMGIFAEALRLVLTQVLLQKKGLTLNPVTSLYYIAPCSFVFLSLPWYVLEKPNIDVSQIQFNFWIFFSNALCALALNFSIFLVIGRTGAVTIRVAGVLKDWILIALSTVIFPESTITGLNITGYAIALCGVVMYNYIKIKDVKAIQPTTDSLPDRITKDWKEKNSSDGGSPRGLELNDEEAPLITSRLSHIGRTQLGNHTAV
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At1g48230.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZDH22_DANRE
Sequence: MGKLKLLNTIAPAYFYAATVVTFALHFLLFTPTIFQSSDVTINPAMLAHISIFLFLMGNALGNYIMTIRNPSESANETVIPVCSPDCPDRIDAHYLLNGRHFCKVCKKVILKRDHHCFFTGNCIGNRNMRYFIMFSIYTSSSCLYSLVIGVAYLTIEYSISFENPLTFLTLLPLSTGYFFLGLISGLQFFLVIMLYIWLGIGLVSVGFCCQQLLLVARGQTWCELQKGQLSECRGTWRANLTDVFGSHWVLGLFVPVPTVETVPGNWQVYHDHKHD
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes.
What are the official names of this protein?
Palmitoyltransferase ZDHHC22, DHHC domain-containing cysteine-rich protein 22, Zinc finger DHHC domain-containing protein 22.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PYRC_SYNR3
Sequence: MTPAPDQLVLRRPDDWHVHLRDDVMLEQVLPATARQFARAIVMPNLRPPVTTVDAAIAYRQRIEAALPDGMAFTPLMTAYLTDDISPDELERGHREGVFTAAKLYPANATTNSAAGVSDLACITAVLERMQAIDMPLLIHGEVTDPDIDIFDREAVFIERHLIPLRRQFPQLRVVFEHITTEQAAQFVVDGDPLMAATITPHHLHINRNAMFQGGLRSDFYCLPVAKRERHRLALRQAATSGDPSFFLGTDSAPHPRAGKESSCGCAGIYNAPYALESYLAVFEAEGALQHFEAFASENGPRFYKLPLNEDTITLKRTAQLVPAQLEGQGLVPFHASEVLDWRLAD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: NAA10_MOUSE
Sequence: MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGKHMVLAALENKAENKGNVLLSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
What is the function of this protein?
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity (PubMed:12888564).  Acetylates amino termini that are devoid of initiator methionine (By similarity).  The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development (By similarity).  Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182).  Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (By similarity).  Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (By similarity).  Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (By similarity).  Acetylates HIST1H4A (By similarity).  Acts as a negative regulator of sister chromatid cohesion during mitosis (By similarity).
What are the official names of this protein?
N-alpha-acetyltransferase 10, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Also present in the free cytosolic and cytoskeleton-bound polysomes.
Protein: KHSE_SULIN
Sequence: MECKRARAYSSSANLGSGFDILSMAHTAFFDTVEICVETKNSENIVIESNSKIPLEPNRNSATYPLVRIMEERGIKASLRVKVIKGIPEGLGLGSSGASATAAVMAFSSLFNLNLSKEDLVRYAMYGEIASSGSPHPDNVAASVFGGVVSVVSVNPVKVVEIPLNYSFNILLFVPLNIHIEEKTKKAREMVPKTVKLSDYINNSRYISSLLIGFVKGERDLIRLGLNDEIVEKARLPLFPYYPKIKEIAIKYDAVGSCVSGAGPSILVLTDKMTDENKIAEEGTKTCNEFNVECEVIKAKIAGGVEVERRN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_MYCA1
Sequence: MTPTRAQLAAFVDHTLLKPEATAADVAALVTEAAELGVYAVCVSPPMVPAAVQAGAGVRVASVAGFPSGKHVSAVKAHEAALAVASGAAEIDMVIDVGAALAGDLDGVRADIAAVRGAVGGAVLKVIVESSALLALADEHTLVRVCRAAEDAGADFVKTSTGFHPSGGASVRAVALMAEAVGGRLGVKASGGIRTAADALAMLDAGATRLGLSGTRAVLDGLG
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JMJ31_CAEEL
Sequence: MQGKNSHLTGITGTTHFTIFGASPRSMSLVKNSQETPPFPGMNSTMRPVEFNSTKQPEAQTIDQEQDAPKSFDFKNQTLGVYSDTVLNPLKNDSFKDELVVDVQKNLPIESLTVSPKSSTDQNCRSTNEAIRIAGFDNFADQLQESNGVFEACPEAHSEQGNESEDFKDLINSETECNIEDVVLPTVHVSTDSEEIISGDVIMNDSNVVSKPKNLEKVETPDVLIGSGSNDKLSDMTEQIGNNQHLEKLISEKTEKSLSDNETTLKPVPVQHTNSVGSSIGTTSGDSEISDDDQKSWSPKNESLDYQPASTSSEFTETTSVANQTESNAGSVDDYCPRTSIDIGLDSSAPSCSSDATREPTPIKKRGRKKKEQSATEPPIPRTKRAYTKNPNTIRKRRMKKNQSDDEEDDGPPKRRTINYQIEFRDASGAWTMAQQLIFVRDFMSKKNDKIVKLSKSRQDRVDKFILQFQKTQDSHYMRAAIQLNTIFPDQGNYRHCQDYLKDLTIRVVVPPKRREGKRKSEVPANPPALLLTGPLYLNFYCTSQEVLEAAGQLLEFHVNAVYKDERLQPPVADKTLLDLERAMYHEQVKDLTDYHKYRIPCPTLTVTTKEEVFSSDFERILNSASITNISGIAKALNIKTELFSLPEIAKCHPELSIDILNQVPQSADGNCDSKGIRCWDVTSYSSKMKLQDFERYMQKEESEAMQAFETISNCTAKELESTCQKLKAERIAAQNAIEGCDETMPWIKFGTNIDLLSENFKKQMNEIEKLPTFLLPNREGNLLNYAGVDVLGINTVQMYAKPIGSRTPAHMENSLMASINWNRGPGTCVWFAVPYEYWGQLEFMIGEHGHKYQDQDYWPSEKELLELGVPVIKFEQKADEMVYVNTGCFHWVQSNSFCINVSWNVGQPNFTQLATSIVAHDHNMLIGNQAHVPLVNLVWNAARQRLFVDDPEMYKAMRGVMIRSLAHSKWYFDLIDHHDYIVGDASEWKLADRVQRCKYCTSEIFNIVRWYTTEDLSVDSYPFCSHCHVANEYKKDRFLKYTWFFSLETLVNIFDAYVPN
What is the function of this protein?
Histone demethylase that specifically demethylates trimethylated 'Lys-27' of histone H3, a mark associated with transcriptional repression, thereby playing a central role in the histone code (PubMed:17713478, PubMed:25124442).  Involved in the transcriptional regulation of the heat shock response, unfolded protein response and possibly other stress response target genes (PubMed:26212459, PubMed:27133168).  Required for gonad development and organization (PubMed:17713478).  Required for the robust transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development (PubMed:25124442).  Acts cell-autonomously in Y-to-PDA transdifferentiation, which depends on the demethylase activity and on recognition of the H3 tail (PubMed:25124442).  Cooperates with set-2 and unc-3 to ensure robust Y-to-PDA transdifferentiation (PubMed:25124442).  Promotes mitochondrial stress-induced longevity (PubMed:27133168).  Involved in lifespan regulation (PubMed:21803287, PubMed:26212459).
What are the official names of this protein?
Lysine-specific demethylase jmjd-3.1, JmjC domain-containing protein 3.1.
What is the protein family that this protein belongs to?
Belongs to the UTX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_ALISL
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRDRRNKKRVFRQLWIARINAAARQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVAFAALVAKANAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: POLH_DROME
Sequence: MSSARSHVSMQNKYDRVVLLVDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGGGIIAVNYAARAKGVTRHMRGDEAKDLCPEIVLCQVPNIREKADTSKYRDAGKEVANVLQRFTQLLERASVDEAYLDITETVNHRMQQMQSGAFALQPQELVNTFAVGYPSIGDYVNKITNRFANPYMDDERYQMSYDQNDLPAVRQSDIRLLIGASVAGEVRAAVKKETGYECSAGIAHNKILAKLAAGMNKPNKQTILPLTETASLFDSLPVGKIKGLGGKFGEVVCETLGIKFMGQVVKFSEVDLQRKFDEKNGTWLFNISRGIDLEAVTPRFYSKSIGCCKKFPGRNNITGLKTLQHWLGELSSEINDRLEKDFIENNRRAKHMVVQYVQDIDGEEVASSRSTALRDYDQESIVRLSLDLIKANTKTFLRPGSESALNNAIKFLGISVGKFETVSSGQNKLQEMFANQAAKKRRVSGDEPGQLPKVEMEKKQKQTDEFKMKSFFANYLQGAKKEDAKADGISANPLAAAAGAPNKNFVEEYKHKLHAAVRTEGTVLTSTPAEFKESFFSQYLKQQKKTGQQGSVTSREDSLDVQELAEELDAIEADNSKDFEEDTEEETELTSDTHMSKPEGQSSDAGQEQDPNTLNDSTGNDLYVETGIVPPTLTEDELKPSTSKRKFDEIESSVSNYKECYVEFAVPNLRTDILPTIKCDQCGANIPDEVKSLQTHRDHHFAQELSRTLRSTEREERTQSRQKISLKPTPPKKSKKTAGSGSSSYSTAPPSNSITKFFRAKPTQEQAPSDPQMNQCPECKAFIKCVDMPEHLDYHVARNLQRELNQQDLRTRTAALNKEKISPVQPKKQSQKKLNSTISASSSGTKTIAQFFSQSN
What is the function of this protein?
DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS) (PubMed:11297519).  Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls (PubMed:11297519).  Inserts one or 2 nucleotide(s) opposite the lesion (PubMed:11297519).  During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase PolZ1/DNApol-zeta to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis (PubMed:22532806).  Particularly important for the repair of UV-induced pyrimidine dimers and for hydroxyurea (HU)-induced DNA damage (PubMed:22532806, PubMed:24553286).  Although inserts the correct base, may cause base transitions and transversions depending upon the context (By similarity).  Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have any lyase activity, preventing the release of the 5'-deoxyribose phosphate (5'-dRP) residue (By similarity).  This covalent trapping of the enzyme by the 5'-dRP residue inhibits its DNA synthetic activity during base excision repair, thereby avoiding high incidence of mutagenesis (By similarity).
What are the official names of this protein?
DNA polymerase eta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to interphase nuclei but undetectable during mitosis.
Protein: EXOL6_ARATH
Sequence: MAMASASSSSSSISVIIFLLLAPLCLSREPPSQIPNGTLDLSLLWYGQFTPTQKERVHDFIESLNFDAKEGLDPKVSAWWKVVESYQERFEVKDIYRQKKSNRTVAPRIKVKVVRSYVDEKMKYGKELTMGNGEKLVETAIGNMSKVVPVVLLSAQVRAHGVGFCDGTCQHNALAKIKGQKEPRRYIMVSNPEVECPGECAWPFHTADKGPRGMTYQPASGEVGADALVIQLATGLADLATNPDLTKSLFKSETTPYNDDVKKNHESSSMYIVDPATKCTRVFGSGAFPGFTGRIRVDPITGGAFNSHGINHLKFLIPSIWDPKTKSCWTPM
What is the function of this protein?
May play a role in a brassinosteroid-dependent regulation of growth and development.
What are the official names of this protein?
Protein EXORDIUM-like 6.
What is the protein family that this protein belongs to?
Belongs to the EXORDIUM family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, apoplast.
Protein: AATC_DAUCA
Sequence: MSSVFANVVRAPEDPILGVTVAYHKDQSPNKLNLGVGAYRTEEGKPLVLNVVKKAEQMLVNDQSRVKEYLPIVGLADFNKLSAKLIFGADSPAIQENRVATVQCLSGTGSLRVGGEFLARHYHEHTVYIPQPTWGNHPKIFTLAGLSVKTYRYYNPETRGLDFEGMLEDLGSAPLGAIVLLHACAHNPTGVDPTIEQWEQIRQLMRSKSLLPFFDSAYQGFASGSLDADAQSVRIFVADGGECLAAQSYAKNMGLYGERVGALSIVCKTADVASKVESQLKLVIRPMYSSPPLHGASIVAAILKDGDLYNEWTLELKAMADRIISMRQELFNALQAKGTPGDWSHIVKQIGMFTFTGLNSEQVTFMTNEYHIYLTSDGRISMAGLSSRTVPHLADAIHAAVTGKA
What is the function of this protein?
Important for the metabolism of amino acids and Krebs-cycle related organic acids.  In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism.
What are the official names of this protein?
Aspartate aminotransferase, cytoplasmic, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL07_ORYSJ
Sequence: MAARRANCALVLVLALALLAARDAGAAAVPKPNWLGGLSRAAFPKRFVFGTATSAYQVEGMAASGGRGPSIWDAFAHTPGNVAGNQNGDVATDQYHRYKEDVNLMKSLNFDAYRFSISWSRIFPDGEGRVNQEGVAYYNNLINYLLQKGITPYVNLYHYDLPLALEKKYGGWLNAKMADLFTEYADFCFKTFGNRVKHWFTFNEPRIVALLGYDQGTNPPKRCTKCAAGGNSATEPYIVAHNFLLSHAAAVARYRTKYQAAQQGKVGIVLDFNWYEALSNSTEDQAAAQRARDFHIGWYLDPLINGHYPQIMQDLVKDRLPKFTPEQARLVKGSADYIGINQYTASYMKGQQLMQQTPTSYSADWQVTYVFAKNGKPIGPQANSNWLYIVPWGMYGCVNYIKQKYGNPTVVITENGMDQPANLSRDQYLRDTTRVHFYRSYLTQLKKAIDEGANVAGYFAWSLLDNFEWLSGYTSKFGIVYVDFNTLERHPKASAYWFRDMLKH
What is the function of this protein?
Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-mannoside, p-nitrophenyl beta-D-galactoside, p-nitrophenyl beta-D-xyloside, p-nitrophenyl beta-D-fucoside, p-nitrophenyl beta-L-arabinoside, oligosaccharides, pyridoxine beta-D-glucoside and the cyanogenic glucosides amygdalin, prunasin and dhurrin.  Possesses pyridoxine transglucosylation activity.
What are the official names of this protein?
Beta-glucosidase 7, Os3bglu7.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Secreted.