PharMolix/UniProtQA huggingface dataset:
Protein: PARE_RICCN
Sequence: MSDLFSFNKEKKNKLVDNNYSAKDIEVLEGLEPVRKRPGMYIGGTDSNAMHHLVSEVLDNAMDEAVAGFASIITITMHHDHSITIFDNGRGIPIDNHPKFPDKSALEVILTTLHSGGKFSNNVYHTAGGLHGVGISVVNALSKHLEIKVYKQGKLYSQSYSKGEKLTDLICEEASKRLRGTSINFTPDPEIFSEKLHFNPKKIYELARSKAYLYRGVTIEWACEVEVQSDIPKKALISFPNGLKDYLSSKITLDNLVIPGIFAGNIESKSDRIKLEWAICWQNNDSSAFVQSYCNTVPTPQGGTHEQGLKSAILRGLKAYGEMIGNKKAANLTIEDILETASVVLSIFIAEPSFQGQTKEKLVSNGVSKPVENIIKDHFDHFLSSDKALATNLLEHVISIAEFRISKKNEKNISRKNATQKLRLPGKLADCTRTSPEGTELFIVEGDSAGGSAKQARNRETQAVLPLWGKVLNVASSTLEKIVNNQAIQDLEIALACGSLKNYKKENLRYEKIIIMTDADVDGAHIASLLMTFFFLRMPKLVEEGHLYLAKPPLYRLTQSNKTYYAGDEEEKAKLMDKLLKASKAKIEVGRFKGLGEMMPAQLKETTMHPEKRSLLKVTLADFQNVDKIVDDLMGKKPEKRFQFIYEQALVKMDKIISELDI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 1 subfamily.
Protein: KPRS_PYRHO
Sequence: MNKVFVIGSGAKHLEEEISKNAKILKTEIKKFPDGEKYVRILEHGEEVIVVQSTYRPQDEHLIETIIIGDALKEAGFEKLKLVVPYLAYSRQDRVTKEGEPISVRAIMKMLGLYYDELYVFDIHNPKTLDFFPGKAVNIYPAKVIAEYFRDKLENGLVLAPDRGALERAKEVANILGLEYSHFEKERISPTEVKMTPVDVNVKGRNVLIVDDIISTGGTMIRAAEILKDLGAEKVFVVATHGVFAEGAIERVSKAVDELAVTNTIPTKVSKISIVPEIMRSILEVKS
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_PSEF5
Sequence: MINEIKKDAQERMKKSLESLAHAFGQIRTGKAHPSILGSVMVPYYGTDTPLSGVANVTVKDSQTLQVVPFERNMLGAIDKAIGSAGLNLNPTNLGELLLIKMAPLTEETRKGFTKQARAAAEDARVAVRNIRRDALGELKKLTKDKEISEDEERRGSAEIDKLIKDFEAQIAKATEEKEKDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRTP1_XENTR
Sequence: MDEANETAQDSVPRIDGYGFVRPAEFDYAFYEEFIARYHVVLTRRAIKWSKLLQQSAAVEKNMKVKRYIRKGIPNEHRSHVWMVVSGAQAQMDMNTGYFRRMFTEGEKNPKLLDLVITDLNRTFPDNVLFQKNANPSLQKDLYNVLVAYGQHNKTVGYCQGMNFIAGYLILVTKDEEKAFWLMDALIGQILPDYYSPAMTGLKTDQEVLGDLVKKKIPSVAQLIETHGVMWTLLVSRWFICLFIDILPVETVLRIWDCLFFEGSKVIFRVALTLIKQSQASIMEARNFPDICDKFKEITKGEFVTDCHYFMQKIFAEPGSLSKTTIDKLREKQRLKLISEEK
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
Growth hormone-regulated TBC protein 1.
Protein: RPOB_PHYMT
Sequence: MEYRNIKYGTKTERRNYSKMNYDIELPNLIEIQTKSFELFLKEGIKKILKDISPIESNNGDLKLYFDDFYLDKPKYNIEEAKNRDITYYAQLFAKARLENVLTKEIKESNILITELPLITPSGTFIINGTERVVISQIVRSSGIYFTKKFDSKIRYLAQLIPTRGAWIEYEQSNKDFLYAKLDRSKKIPLNKFICCLGFDTKEKIESTFGYNKFLDLSLKKDQILNINEAIIELHSKLHRGEKVPVDVAREFIFSKLFYAKKYDLLAVGRYKFNQKLDVLKRIKNTYLAKDLIDPETNEIFLSKKTFLNEEIIEKLKNKRNCFTFELVNADNNLENEINEEILTYANYNKDKILELYIKDNIINIKTGEILVEKDTLITEQVMNIIRKNGQFIHDKVSKYFLCNKDLYQKHKERKGVFNEVLEVYILDNLGNPKPTIKVIGNIQSENNKQHITVSDIIASISYYLNLYEDIGKTDDIDHLGNRRLRLIGELLTNQFRLGLIISEKNIKDKMSISKFNNITVNSLVNFTSLSAIIKTFFNSSRLSHFMDQINPLAELTQKRRVSALGTGGIDRDRAGIEIRDINNSHYAKLCPIETPEGPSIGLIASLSTYARVDKYCFIQTPYLKVIKNEQGQPKVSEHIDYLTADQEEKEVIASVTYLNSDNTFKEKKIIARKNGETGLHEIDKITYIDVSPKQIVSVATSSIPFLEHNDASRALMGANMQRQAVPLLIPESPIVGTGIEHRIAKDSGCLILAKNSGYVTYADAQKIVITEKPKKTITINNEVIYKNEEEFNYEKAKILHKKNVFSCQTEYKLINFAKSNQDTLILQKPLVLDGDFVNKNDIITDGPATHKEELALGRNVTVAFMTWEGYNYEDAIIISEDLVKNDIYTSVHIDKYEIQTRELKKGAGVEQITREVPNVSAEAIKNLDERGIIIPGSEVKEGDILVGKITSQGMVEQTAYERLINVIIGEKSREHKDSSLRVPCGEGGIVQSVKYFSKENNDILPPEVNENIRVYIAKKRKIKEGDKIAGRHGNKGVISLILPKEDLPYMKDGTTIDIILNPLGVPSRMNIGQILEMHLGIAAQKLNIKVATPVFDGVNNDDLRKIIKEAKLSLDGKMTLYDGRTGEPFDSSISVGVMYMIKLSHMVEDKLHSRNIGPYTLMAQQPMGGRNQNGGQRFGEMEVWSLYAYGAANSLQEILTIKSDDIIGRQKTYSAITNGLPLPKPSIPESFRVFAKELQALGLYVELINSKTKENEILKSLVENQKKGSNNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: VSIG1_MOUSE
Sequence: MMVFAFWKVFLILNCLAGQVSMVQVTIPDTFVNVTVGSNVTLLCLYTTTEKSLEKLSIQWSFFHNKEMEEPISIYYSEGGQASAIGQFKDRIIGATNPGNASITILHMQPADSGIYICDVNNPPHFVGKNQGLLDVTVLVKPSKPFCTIQGRPEAGHPISLSCLSAFGTPSPLYYWYNIEGNTIVPVKESFNTATGVLVIGNLTNFEQGYYQCTAINSLGNSSCEIDLTSSHPEVGIIIGALVGALIGAAVIICVVYFARNKVKSKQQKNLNSSTELEPMTKVHHPQQSEAISADGVQLEGTLPSSIHAGHNTEPTTTAVLEPEYEPNPPLETTTQPDPEPEGSVPVLAPEAEIQPHPELDPETETEPEPEPEPKPEPEPEPELEPDPQSGVIIEPLSKAGEDTVKA
What are the official names of this protein?
V-set and immunoglobulin domain-containing protein 1, Cell surface A33 antigen, Glycoprotein A34.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NEDR_MICVI
Sequence: MCWGRSWTFGRSSSKGWRPTSSASSYDEHRADLSTLADEMVDLASQGRDGLEVDRAFHLKLMEPLGNDLILQLTEAFWQVQAIVAPTLRTEPEDRLITAQRHRAIVDAATAGDPEALRSAIADHYAPIRTSIARAVQS
What is the function of this protein?
May serve as a transcriptional regulator.
What are the official names of this protein?
Putative transcriptional regulatory protein NedR.
Protein: GYRA_SALTY
Sequence: MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE
What is the function of this protein?
Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BRASB
Sequence: MGQKINPIGLRLGINRTWDSRWFAGKAEYGKLLHEDVKIREILHKELKQAAVARIVIERPHKKCRVTIHSARPGVVIGKKGADIDKLRKRVADITSSDVVINIVEIRKPELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADIDYGVATAFTTFGTCGVKVWIFKGEILEHDPMAQDKRMNEGGGESSQPRSRRDAA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RSMA_STRZP
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLEEFASLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLB_CYAPA
Sequence: MKLAYWMYTGPAHIGTLRIASSFKNVHAIMHAPLGDDYFNVMRSMLERERNYTPVTTSVVDRNVLARGSQEKVIDNILRKDKEEQPDLIVLTPTCTSSILQEDLQNFVEQASLNSMADVLLADVNHYRINELQACDKTLEQIVRFYIEKNRASLTLEKVKTLLPSVNLIGISSLGFHNNHDTRELKKLFELYEIILNCSLPQGTTVKTLINLPKAWLNILPYRELGLLTSKYLNKEFGLLSLVILPMGNINLNRFLKKLLFSLKLENNTITKVINIKLLKLLNLNWIKKEAIKSKLKRKKAIIFGSSNHVATLTKLLSKEIGLEIILCGTYCKSESKWFSEQVQNYCNKILITEDHTMISNEISKLKPDVIFGTQMERHIGKRLGIPCGVISSPIHIQNFPLSYKPMVGYEGVKTIMDLLFNSLNLKDRKNSFTLFNEII
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: YGJQ_ECOLI
Sequence: MLRAFARLLLRICFSRRTLKIACLLLLVAGATILIADRVMVNASKQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKNYDEASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRAIWLAKQYGIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMIGPFSEHGCPAQK
What are the official names of this protein?
Uncharacterized protein YgjQ.
What is the protein family that this protein belongs to?
To E.coli SanA.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y3403_BRUSI
Sequence: MTEITDRYFNDVIARLSGLRDRLAAQMEKAADLIAAAARADRRVYVFGTGHSHMMAEELHYRAGGLAITVPILCGSIMLQDGAVASSHFERIEGAVRPILDRYGIRDGDVLVVVSNSGVNAAPIEAARYAREKGAAIIAPTSVAYSNTIARGRTQLLSLADVVLDNDAPSGDAVLEIAGSALKVGPVSTALGVTILNAVFADVAARLVGEGDAPIYLSANMPGSGDINRSLVERYRDRNPHL
What are the official names of this protein?
UPF0309 protein BSUIS_B0903.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: CD226_MACMU
Sequence: MDYPTLLLALLHVYRALCEEVLWHTSVPFAENMSLECVYPSVGILTQVEWFKIGTEKDSIAIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQSDGFEAAVPPNSHIVSEPGKNITLTCQPQMTWPVQEVRWEKIQPHQIDLLTYCDLVHGRNFTSKFPRQIVSNCSHGSWSFIVVPDVTASDSGLYRCHLQASAGENETFVMRLTVAEGQTDNQYTRFVTGGTVLLLLFVISITTIIVIFLNRRRRRERSDLYTESWDTQKAPKNYRSPISASQPTNQSMDDTREDIYVNYPTFSRRPKTRV
What is the function of this protein?
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.  Cell surface receptor for NECTIN2.  Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG.  Competes with PVRIG for NECTIN2-binding.
What are the official names of this protein?
CD226 antigen, Platelet and T-cell activation antigen 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HISZ_BORPA
Sequence: MGNWLLPEGLADVLPAEARRIEELRRELLDLYRTYGFELVAPPLVEYIDSLLSSTGSDLNLRTCKLVDQLSGRTLGVRADMTSQVTRIDAHLLNRAGVTRLCYCGSVLHARPADLLSSRELLQIGAEIYGHAGFEADLEIIQLVMDTLATAGVRNARLDLCHSGVMRAIFDADPQASRHAGDLCTLLREKDVPGLAELASRVDGLGEDTVRALQALATLYGGPEIIARARRELPAVPGMAQALDALQALVDAMPGVTLSVDLADVGGYGYHSGVTFAVYGEDWHDALVRGGRYDDVSRAFGRARPATGFSLDLRKLAAGLTPAEPARAVRAPWGQDPALTDAVRRLRRSGEIVVQVLPGHEQGLDEFVCDRELALQDGAWTVRTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_SHESM
Sequence: MSDISDANKLKHRFRGYFPVVIDVETAGFNSQTDALLEIAVTLLKMDDEGLLGIDKTLHFNIEPFEGANLEPEALAFNGIDPTNPLRGAVSEKEAFLEIFKAVKKAQKASDCHRSIIVAHNAAFDHGFVSKAIERCDLKRSPFHPFATFDTATLAGLAIGHTVLAKACIMAGIPFDNKEAHSALYDTERTAELFCYIVNRWKHLGGWPLLAAGESEDTDGEE
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: PSBA1_TRIEI
Sequence: MTTTLQQRESANVWEKFCSWVTSTDNRIYVGWFGVLMIPTLLTATICYIIAFVAAPPVDIDGIREPVAGSLMFGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGIFTYMGREWELSYRLGMRPWICVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVVGIWFTALGVSTMAFNLNGFNFNQSIIDSSGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSIKG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 1, PSII D1 protein 1, Photosystem II Q(B) protein 1.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: GPMA_NITWN
Sequence: MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTLIRAQHTLDLVLKELDQTGIPVRKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYDVPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHGNSLRALVMVLEKLSPEQILARELATGAPVIYRLNADATVASKLDLAA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: FETP_SALPB
Sequence: MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CXA1_CHICK
Sequence: MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKREEELKVVQNDGVNVDMHLKQIESKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAIYTCERDPCPHRVDCFLSRPTEKTIFIVFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKTDPYSHSGTMSPSKDCGSPKYAYYNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFADEHQNTKKLASGHELQPLTIVDQRPPSRASSRASSRPRPDDLEI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  Plays an essential role in gap junction communication in the ventricles.
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and proper localization at ICD is dependent on TMEM65.
Protein: PYRB_HYPNA
Sequence: MAPPRPDYTFTHEHLLGIEGLHPLDIGHILDLADSYAEKTRAGVRPDPVLTGKTVVNLFFETSTRTMSSFEIAARRLGAHVISMPIANSSVKKGETLIDTAMTLNAMKPDALVIRHSASGGAKLLSRKVDCAVINAGDGTHEHPTQALLDLLTIRRVKNRIEGLKVVICGDIAHSRVARSTTMALHLMGARVHLCGPKTLIPPGTETWGAESAGTDFDKVLKGADVVMMLRLQLERMNGSFLPSRREYFRYFGLTAERLALAKPNATVMHPGPMNRGVEIESTIADGPSSVITQQVEMGVAVREAVLHLLAGGKS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UN93B_MOUSE
Sequence: MEVEPPLYPVAGAAGPQGDEDRHGVPDGPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVVKNVLAASTGVTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNNYLYDLNHTLINVQSCGTKSQGILNGFNKTVLRTLPRSKNLIVVESVLMAVAFLAMLMVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFALGYGVCSMGLERLAYLLIAYSLGASASSVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPMKAKLAVLLVTLVAAAASYLWMEQKLQQGLVPRQPRIPKPQHKVRGYRYLEEDNSDESDMEGEQGQGDCAEDEAPQAGPLGAEPAGPCRKPCPYEQALGGDGPEEQ
What is the function of this protein?
Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling.  Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades.  May play a role in autoreactive B-cells removal.
What are the official names of this protein?
Protein unc-93 homolog B1, Unc-93B1.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Colocalizes with LAMP5 in large endosomal intracellular vesicles (By similarity). Relocalizes from endoplasmic reticulum to endosome and lysosome upon cell-stimulation with CpG dinucleotides.
Protein: Y009_HISS2
Sequence: MTQQNTTLMPREKLLKYGASSLDDKELLAIFLRTGIKNCPVMQLSELVLAHFSSLRGLINADQKHFCQMKGLGITQFVQLQACTEMTKRYLLQELQFAQEFTSPDTVRMYLQTELENKDREIFMVLFLDNQHRLIKKEEMFLGTINQANVYPREIIKTALFCNAAALILAHNHPSGVSTPSMADRKMTENIKQLSELMEIRVLDHFIIGKGNYFSFAEQGWI
What are the official names of this protein?
UPF0758 protein HSM_0009.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RS2_SALTY
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKISARKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: EFTU_MYCAP
Sequence: MAKLDFDRSKEHVNIGTIGHVDHGKTTLTAAIATVLAKKGLSEAKSYDAIDNAPEEKARGITINTSHIEYNTEKRHYAHVDCPGHADYIKNMITGAAQMDGSILVVAATDGAMPQTKEHVLLAKQVGVPKMVVFLNKCDMIKPEDAEMIDLVEMEVRELLTKYGFDGDNTPFVRGSALQALQGKPEYEENILELMNAVDTWIETPVKDFEKPFLMAVEDVFTISGRGTVATGRVERGRLSLNEEVEIVGLKPTKKTVVTGIEMFRKNLKEAQAGDNAGLLLRGVERSAIERGQVLAKPGSIVPHAEFEAAIYALTKEEGGRHTPFFVNYKPQFYFRTTDVTGGLEFEKGREFVQPGENVNLKVKLIAPIAVEEGTKFSIREGGRTVGYGSVTKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFS_HALH5
Sequence: MIYLDYCATTPMSDYVKDVYVTVASQFYGNPNSLHDVGYEASNILEQCKRQIANLLHIDPAGIFFTGSASEANFLTIVSLALAHRRKGRHLITTKCEHPSVLSTFRYLESQQFDVSYVPVNRYGQVSVDALMGTIREDTILVSIAHSQSVLGTIQSLETFAEPLVTYDILFHSDCTQSIGKVDVPIRQLHSLTMSGHKINGPKGIGLAYVDPAIQWEPFLSGVTQQSGFRQGTVDIPSVAAFTAAIEESFQHRTAYDQHITKLHHQFKEKMMEWPMILEGHPSNRLKHHFGLRLHGMEGQFVMLEANRAGFAISTGTACSSSHHEPDPVFAAIGRTKEEADQFFRVSFGISTTEQEFNAFIDFLQQLIDRKGEPM
What is the function of this protein?
Catalyzes the removal of elemental sulfur from cysteine to produce alanine.
What are the official names of this protein?
Putative cysteine desulfurase NifS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
Protein: NU2C1_ORYSJ
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFQGSFIFPECILIFGLILLLMIDLTSDQKDRPWFYFISSTSLVISITALLFRWREEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKRDLRSNEATMKYLLMGGASSSILVYGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGLGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAALALATRILDIPFYFSSNEWHLLLEILAILSMILGNLLAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIVKLLMTGRNQEITPYVRNYRRSPLRSNNSIELSMTVCVIASTILGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.