PharMolix/UniProtQA huggingface dataset:
Protein: LAX1_MEDTR
Sequence: MLSEKQGEETMMSSLNETIELNEEREEEKGASPGSGFKNFLWHGGSVYDAWFSCASNQVAQVLLTLPYSFSQLGMISGIIFQVFYGLMGSWTAYLISILYVEYRSRKEKENVSFKNHVIQWFEVLEGLLGPYWKAIGLAFNCTFLLFGSVIQLIACASNIYYINDHLDKRTWTYIFGACCATTVFIPSFHNYRIWSFLGLGMTTYTAWYMTIAAIVHGQVENVVHSGPKKMVWYFTGATNILYTFGGHAVTVEIMHAMWKPQKFKAIYFFATLYVFTLTLPSAIAVYWAFGDQLLDHSNAFSLLPRNAWRDAGVILMLIHQFITFGFACTPLYFVWEKVIGMHDTKSIFLRALARLPVVIPIWFLAIIFPFFGPINSAVGALLVSFTVYVIPASAHMLTYRSASARQNAAEKLPKVIPSWTLMYVINAFVVIWVTIVGFGFGGWASMTNFIKQVDTFGLFAKCYQCPPKLPASNHTMHH
What is the function of this protein?
Carrier protein involved in proton-driven auxin influx.  Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex (By similarity).  May be involved in lateral roots and nodules formation.
What are the official names of this protein?
Auxin transporter-like protein 1, AUX1-like protein 1, MtLAX1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLHD_ECO45
Sequence: MGIMHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_ACISJ
Sequence: MSLRLGQIVDALGGSLEGGERDTEILRIAPLESSGPGDLSFLSNPRYQSQLAASQAACVIVAPAMRNAALERGACIVVEQPYTYFAHVTQLWVRAHGQGAPAGIHPSAVVDPQARVAPTASIGPLCVVERGAVIGAHTVLKSRVTVGERCTVGERCILHPGVVIGADGFGFAQQRGEWIKIEQLGAVRIGNDVEIGANTCIDRGALDDTVIEDGVKLDNLIQIAHNVHIGRHTAMAGCSAVAGSTRIGAHCTIAGAASIVGHLQLADNVHISTNTVVTHSITQPGQYTGVFPMDDNAKWEKNAATLRQLYRLRERIKALEQTRKDG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LUXO_VIBVU
Sequence: MVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLDLRLPDMTGMDVLHAVKASHPDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTIDSAASSKASIFITGESGTGKEVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGGTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRERGEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWPGNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKESVQPDLSELISVRDICPLWLTEKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA
What is the function of this protein?
Involved in the regulation of different processes depending on the cell density.  Acts together with sigma-54 to repress, perhaps indirectly, some genes (By similarity).
What are the official names of this protein?
Regulatory protein LuxO.
Protein: MNME_HAEIG
Sequence: MKETIVAQATAPGRGGIGILRVSGPLATEVAQAILGKCPKPRMADYLPFKDADGTILDQGIALYFKSPNSFTGEDVLELQGHGGQVVLDLLLKRILQIDGIRLARPGEFSEQAFLNDKFDLAQAEAIADLIDATSEQAARSALKSLQGEFSKKVNELVDSVIYLRTYVEASIDFPDEEIDFLADGKIEANLRSIINQLEDVRAEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDATDEVERIGISRAWTEIEQADRIILMLDSSDPESVDLSKVRSEFLAKLPSTLPVTIVRNKIDLNGEQASESEQSGYQMISLSAQTHDGVKLLREHLKQAMGFQTGMEGGFLARRRHLDALDKAAEHLQIGLVQLTEFHAGELLAEELRLVQSYLSEITGQFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_LACP7
Sequence: MEKTMEKIVALAKARGFVYPGSEIYGGLANTWDYGNLGVELKNNVKKAWWTKFIQQNPYNVGVDCAILMNPQTWVASGHLGSFSDPLMDCKECRERFRADKIIEDYATEKNLTLEGSVDAWSHEEMSAYIEKNNIPCPTCGKHNFTDIRQFNLMFKTFQGVTEDAKNTVYLRPETAQGIFVNFKNVQRTSRKKIPFGIGQVGKSFRNEITPGNFTFRTREFEQMELEFFCEPDTDLEWFAYWKQFCIDWLQTLGIKEDEMRVRDHEKEELSFYSKATSDIEFLFPFGWGELWGIADRTDYDLTQHQNVSKEDLSYFDDEKGQRYIPYVIEPSLGADRVTLAFLCAAYDEEEIAEGDVRTVLHFHPAIAPVKIGVLPLSKKLSENAEKIYTDLSKYYNCEFDDRGNIGKRYRRQDEIGTPFCITYDFDSETDGAVTVRDRDTMEQERIKIEDLKAYFEKKFEF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SVS3A_MOUSE
Sequence: MKSIFFSLSLLLLLEKKAAGIELYAGGTKGHFLVKTSPLMFIGKNQFLYGHKEEQEEAPEESIFVQTKHHEYGQDADADMGGALSSQELTSLKEDIVCEEEDELAQQKSQLPSQSQIKSQTQVKSYAAQLKSQPGQLKTIGQVKSQTMLKSHGAPLKSFKARLNLREDIPQQVKGRGYGLAEDLAQVRQQPAKVHRLKGKHRQSRKTAAFYPQFRRRSRPYPRYFVQFQEQLQGSVHHTKSFYPGPGMCYCPRGGVILYQDAFTD
What is the function of this protein?
Component of the copulatory plug.
What are the official names of this protein?
Seminal vesicle secretory protein 3A, Seminal vesicle secretory protein III, SVS III.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_DROGR
Sequence: MVTNKKEDEALSTTSAVTGLPQKRFYRQRAHSNPIADHSFDYPARPEDVDWRSLYPSINDEQQVEFADIGCGYGGFLVTLGEMYPKKLSIGMEIRVKVSDYVVDRIAALRLKNSETAAYQNIACIRTNAMKYLPNYFRKSQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYVLRTGGLVYTMTDVEDLHKWIVSHMTQHPLYERLSDEATKADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BCORL_HUMAN
Sequence: MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQAEVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRWSQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
What is the function of this protein?
Transcriptional corepressor.  May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6.  This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.
What are the official names of this protein?
BCL-6 corepressor-like protein 1, BCoR-L1, BCoR-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the BCOR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VP8_FOWPN
Sequence: MNDLLLENLFGEKALCAQVTRDQLLEIIAAGARSKFPKSLLSMYRVTPRVMTRYPLKLITNESITGVVITTVYNLKKNLNIPQNNKLTTQDIERYYLDKSVEVINLMVGNTSLGDLACGRPRRTKSSKKKDPVIFLGISAPLILVMNSKKSINTYIQDKKSDPSSDYVNINPGIGVLENYGNTYLLDIHNPSSVLTISTIYGLDNNMELKKLSTASEIDAYQDVNIGKSVDLKKFNEIFNTMKKHLSLSNFSI
What is the function of this protein?
Major core structural protein.
What are the official names of this protein?
Core protein VP8, 25 kDa major core protein, L4 core protein, P25K.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae VP8 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: RDL2_YEAST
Sequence: MFKHSTGILSRTVSARSPTLVLRTFTTKAPKIYTFDQVRNLVEHPNDKKLLVDVREPKEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHDKELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK
What is the function of this protein?
Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase RDL2, mitochondrial, Altered inheritance of mitochondria protein 42, Found in mitochondrial proteome protein 31, Rhodanese-like protein 2.
Protein: LEA34_GOSHI
Sequence: MSQGQPRRPQQPAGQGENQEPIKYGDVFNVSGELANKPIAPQDAAMMQTAETQVLGQTQKGGTAAVMQAAATRNEQVGVVGHNDITDIAGEQGVTLAETDVAGRRIITEAVAGQVVGQYVQATPVMTSQVGVVLQNAITIGEALEATAKTAGDKPVDQSDAAAVQAAEVRATGSNVIIPGGLAATAQSAAAHNATLDRDEEKIKLNQVLTGATAKLPADKAVTRQDAEGVVSAELRNNPNVATHPGGVAASMAAAARLNENVNA
What is the function of this protein?
LEA proteins are late embryonic proteins abundant in higher plant seed embryos.  There are two subsets of LEA proteins (5a and 5b), the first ones are expressed when the cotyledon weight reach 80 mg and the second set are expressed above 100 mg.  The function of those proteins is not known.
What are the official names of this protein?
Late embryogenesis abundant protein D-34, LEA D-34.
What is the protein family that this protein belongs to?
Belongs to the LEA type SMP family.
Protein: CDK4_BOVIN
Sequence: MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEGDAE
What is the function of this protein?
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity.  Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 4, Cell division protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane. Note=Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus (By similarity).
Protein: CH10_SYNJA
Sequence: MAAVTLNVSTLKPLGDRVLVKIAQQDEKTAGGIFLPDTAKEKPQVGEVVAVGPGKRNDEGKLIPMELKAGDRVLYSKYAGTEVKLGSDEYVLLAERDILAIVQ
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ERWT9
Sequence: MITTWPAPAKLNLFLYITGRRPDGYHDLQTLFQFLDYGDTLTIETNQSGTLRLLSPLDGVPDDDNLIIRAAKLLREQAQKHSTLPANAGANLAVTKRLPMGGGLGGGSSNAATVLVALNHLWQTGFSLHQLAAFGLQLGADVPVFVQGFAAFAEGVGERLMPVSPPEKWYLVMHPGVSIATPLVFNDPLLTRNTPRREISALLSAEFRNDCEAVVRNRFREVEQLVSWLLEYAPSRLTGTGACVFAEFDTESAARQVFELAPAGLQGFIAQGVNISPLHRTLSEQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: AMPL1_ORYSJ
Sequence: MPNVVDPPQISFAAKDMDLTEWEGDILAVLVTETDVSKATSSSSRFTNAAAALAKLDGELGGLLSEASAEEEFAGRAGQSVALRLPTAPGLHGFKRVCLVGVGNNMPSSAAACRSTGETIAAVAKSAQARSAAVALASPPPGWVQGEDLRLNAAAAVASGVVLGLHEDRRYKSDSKKVHLKQVDLIGFGSGQEMGRKLQYANHVSSAVIFAKELVNSPANVLTPAVLAEEASNIASSYSDVLTATILDEEKCRELKMGSYLAVAAASANPPHFIHLCYKPPGGNVKRKLAIVGKGLTFDRFYLSLDNLLIVTKFVCIGGYNIKIGAVTTIELMKKDMGGSAALFGAAKALGQIKPPGVEVHFISAACENMISGTGMRPGDIVTASNGKTIEVDNTDAEGRLTLADALVYACKLGVDKIIDLATLTGYCRIALGPSIAGILTPSDELDKEVAAAYEASGEKFWRLPLEESYWEQMKSSVADMLNTGSPLGGAITAGLFLKQFVDEKVKWMHVDMAGPVWNYKKQEATGFGVSTLVEWVLINSS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Putative leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP 1, Proline aminopeptidase 1, Prolyl aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEEP_BACTN
Sequence: MPNRRDFLKTAAFATLGSGIAVSQVLAGECMPSAIHINKYGIGGKMKMTFFPYELKLRHVFTVATYSRTTTPDVQVEIEYEGVTGYGEASMPPYLGETVESVMNFLKKVNLEQFSDPFQLEDILSYVDSLSPKDTAAKAAVDIALHDLVGKLLGAPWYKIWGLNKEKTPSTTFTIGIDTPDVVRAKTKECAGLFNILKVKLGRDNDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPKEQLDDIAWVTQQSPLPVFADESLQRLGDVAALKGAFTGINIKLMKCTGMREAWKMVTLAHALGMRVMVGCMTETSCAISAASQFSPAVDFADLDGNLLISNDRFKGVEVVNGKITLNDLPGIGVMKI
What is the function of this protein?
Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and may play a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component.  Is also able to catalyze the epimerization of L-Ala-D-Asp, L-Ala-L-Glu, L-Ala-L-Ser, L-Ala-L-Pro, L-Ala-L-L-Val, L-Ala-L-Thr, L-Ala-L-Leu, L-Ala-L-Ile and L-Gly-L-Glu (in vitro).
What are the official names of this protein?
L-Ala-D/L-Glu epimerase, AE epimerase, AEE.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: HTPG_ALKMQ
Sequence: MIKKEFKAESKRLLDLMINSIYTHKEIFLRELISNSSDAIDKIYYKALTDESMIFNKEDYYIKITTDKENKMLIISDMGIGMTKEELEENLGVIAQSGSFTFKKENEIKDGFDIIGQFGVGFYSAFMVADSVTVISKALGSDQGYKWESIGAEGYTIEPYEKESVGTEIILKLKENTEDEKYEDYLEAYRLKTIIKKYSDFIRYPIKMDIETSKPKEGAEGEYEEIVEEQVVNSMVPMWRRNKNELTKEDYDLFYSEKHYGFDKPLKHIHISADGAVRYNAILFIPEKIPYDFYTKEYEKGLELYSSGVLIMNKCSDLLPDYFSFVKGMVDSEDLSLNISREMLQHDRQLKIIAKKIKEKIKSELELLLKNERERYEEFYDSFGRQIKYGVYSDFGQNKETLKDLLLFYSSKEKKMVTLDEYVGRMKEDQKYIYYASGDSIEKIDKMPQTELLAEQGYEILYFADDVDEFAIRVLVDYKEKEFKSVSSGDLGIEEKDEKEEQEEQTQGSKEVFAFMKEALSQKVKDVRPSKRLKNHPVCLATDGDVTIEMEKILSAMPNNQEIKAERVLEININHDVFKTLKEAFDNDQEKLKIYTNVLYNQALLIEGLTINDPVEFTNDICKLMS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TALDO_MOUSE
Sequence: MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK
What is the function of this protein?
Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway.  Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate (PubMed:17003133, PubMed:27703206).  Not only acts as a pentose phosphate pathway enzyme, but also affects other metabolite pathways by altering its subcellular localization between the nucleus and the cytoplasm (PubMed:27703206).
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. Actively transported into the nucleus in an importin alpha/beta-dependent manner (PubMed:27703206). Exported into the cytoplasm by CRM1 (PubMed:27703206). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Imported into the nucleus when incorporated in isoform 1/isoform 2 homodimer.
Protein: ATPE_NEIMF
Sequence: MSIMQVEVVSSEQNIYSGEASFVVVPTVQGELGIYPRHEPIMSLVRPGALRLTVPGEDKEVLVAVSGGVLEVQPDKVTVLADVAVRSAEMDQARAEEAKKAAEAGISQAKDDKALAEAHKALAAAIAQLKTLDYIRSHKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPPM_MYCTU
Sequence: MARTRRRGMLAIAMLLMLVPLATGCLRVRASITISPDDLVSGEIIAAAKPKNSKDTGPALDGDVPFSQKVAVSNYDSDGYVGSQAVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNIVILEGRADLTSVSDPDADVELTVAFPAAVTSTNGDRIEPEVVQWKLKPGVVSTMSAQARYTDPNTRSFTGAGIWLGIAAFAAAGVVAVLAWIDRDRSPRLTASGDPPTS
What is the function of this protein?
A putative lipoprotein that seems to be specialized for the initial steps of macrophage infection (PubMed:27220037).  A non-acylated fragment (residues 26-185) binds phosphatidyl-myo-inositol mannosides (PIMs) (PubMed:27568926).  Limits, in a TLR2-dependent fashion, bacterial uptake by host (mouse); this effect may be mediated by nonacylated fragment 26-185 (PubMed:27220037).  Plays a TLR2-dependent role in host phagosome maturation arrest (PubMed:20844580, PubMed:27220037).  Plays a TLR2-independent role in chemokine production during the first 24 hours of mouse infection (PubMed:27220037).
What are the official names of this protein?
Protein LppM, Putative lipoprotein LppM.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Membrane; Single-pass membrane protein. Secreted, cell wall. Secreted. Note=Mature form (about 28 kDa) is associated with the cell wall and membrane fraction, secreted form is seen after 1 week axenic culture in Sauton's medium without detergent, this form is about 20 kDa (PubMed:27568926). May not be acylated, cell wall association is unchanged by mutation of the putatively acylated residue, and the mutant's migration does not change (PubMed:27568926).
Protein: SVBP_TAEGU
Sequence: MDPGAGARKERPKPREPAARLEKAKQRSAQQELKQRQRAEIYALNRVMTELEQQQFDSFCKQMQGSGE
What is the function of this protein?
Enhances the tyrosine carboxypeptidase activity of vash1 and vash2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin.  Also required to enhance the solubility and secretion of vash1 and vash2.  May play a role in axon and excitatory synapse formation (By similarity).
What are the official names of this protein?
Small vasohibin-binding protein, Coiled-coil domain-containing protein 23.
What is the protein family that this protein belongs to?
Belongs to the SVBP family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cytoplasm, cytoskeleton. Note=Detected both intracellularly and extracellularly. Within cells, localizes mainly to the apical part of the cell.
Protein: XYNA_NEOPA
Sequence: MRTIKFFFAVAIATVAKAQWGGGGASAGQRLTVGNGQTQHKGVADGYSYEIWLDNTGGSGSMTLGSGATFKAEWNASVNRGNFLARRGLDFGSQKKATDYSYIGLDYTATYRQTGSASGNSRLCVYGWFQNRGVQGVPLVEYYIIEDWVDWVSDAQGRMVTIDGAQYKIFQMDHTGPTINGGSETFKQYFSVRQQKRTSGHITVSDHFKEWAKQGWGIGNLYEVALNAEGWQSSGIADVTKLDVYTTQKGSNPAPTSTGTVPSSSAGGSTANGKKFTVGNGQNQHKGVNDGFSYEIWLDNTGGNGSMTLGSGATFKAEWNAAVNRGNFLARRGLDFGSQKKATDYDYIGLDYAATYKQTASASGNSRLCVYGWFQNRGLNGVPLVEYYIIEDWVDWVPDAQGKMVTIDGAQYKIFQMDHTGPTINGGSETFKQYFSVRQQKRTSGHITVSDHFKEWAKQGWGIGNLYEVALNAEGWQSSGVADVTLLDVYTTPKGSSPATSAAPRTTTRTTTRTKSLPTNYNKCSARITAQGYKCCSDPNCVVYYTDEDGTWGVENNDWCGCGVEQCSSKITSQGYKCCSDPNCVVFYTDDDGKWGVENNDWCGCGF
What is the function of this protein?
Hydrolyzes xylans into xylobiose and xylose.
What are the official names of this protein?
Bifunctional endo-1,4-beta-xylanase A, XYLA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.