PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_BRUA1
Sequence: MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ECOT_ECOLI
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.  The strength of inhibition does not appear to be correlated with a particular protease specificity.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYGL_BOVIN
Sequence: MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQYYYEKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQIEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTEAGTKWTDTQVVLALPYDTPVPGYLNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFDSSNSTKTAFDAFPDQVAIQLNDTHPSLAIPELMRIFVDIEKLPWSKAWEITQKTFAYTNHTVLPEALERWPVELVEKLLPRHLQIIYEINQKHLDKIAALFPKDVDRLRRMSLIEEEGGKRINMAHLCIVGSHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQLTKLNSFLGDDIFLREISNVKQENKLKFSQFLEKEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVVTMYNRIKKDPKKLFVPRTVIIGGKAAPGYYMAKLIIKLITSVAEVVNNDPVVGSKLKLIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIEDVAALDKKGYEAKEYYEALPELKLAIDQIDKGFFSPKQPDLFKDLVNMLFYHDRFKVFADYEAYVKCQEKVSQLYMNPKAWNIMVLKNIAASGKFSSDRTIKEYARDIWNMEPSDIKISLSSDPSGGANKANGK
What is the function of this protein?
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
What are the official names of this protein?
Glycogen phosphorylase, liver form.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TOP1_STAEQ
Sequence: MADNLVIVESPAKAKTIEKYLGKRYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKDLKKHAKKAKKIFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKDSFKHPRGIEMDLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWSIEGEFRYKKSKFTAKFLHYKNKPYKLNNKDDVQRITEALNGDQFEITNVNRKEKTRYPAHPFTTSTLQQEAARKLNFKARKTMMLAQQLYEGIDLKRQGTVGLITYMRTDSTRISTSAKSEAQQYINDKYGEQYVSQRKSSGKQGDQDAHEAIRPTSTMRTPDDMKAFLTRDQHRLYKLIWERFVASQMAPAILDTVALDVTQNDIKFRANGQTIKFKGFMTLYVEAKDDKENDKENKLPQLDKGDKVTATKIEPAQHFTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFIPTELGEIVYEQVKEYFPEIIDVEFTVNMETLLDKIAEGDMNWRKVIGDFYNSFKQDVERAESEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKTIGVTCPKCNEGDVVERKSKKNRIFYGCSRYPECDFISWDKPVGRDCPKCHHYLVNKKKGKSSQVVCSNCDYEEEVQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: UBCP1_RAT
Sequence: MSLPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEVVEVENREENLLKISRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAKLDDFLELNHKYWERYLSKKQGQ
What is the function of this protein?
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity.  Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1.  Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly.  Has also been reported to stimulate the proteolytic activity of the 26S proteasome.
What are the official names of this protein?
Ubiquitin-like domain-containing CTD phosphatase 1, Nuclear proteasome inhibitor UBLCP1.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with nuclear proteasomes.
Protein: TPIS_KLEPN
Sequence: MRHPLVMGNWKLNGSRHMVNELVANLRTELAGVSGCAVAIAPPEMYLDLAKRAAEGSHIHLGAQNVDVNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAVFEGVVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNAGNAAELFTQPDIDGALVGGASLKADAFAVIVKAAEAAKKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFIT1_MACFA
Sequence: MSTNGDNHQVKDSLEQLRCHFTWELFIEDDEMPDLENRVLDQIEFLDTKYNVGIHNLLAYVKHLKGQNEEALKSLKEAEDLMQKEHANQASVRSLVTWSNFAWVYYHMGRLAEAQAYLDKVENICKKPSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKALEGDHENPEFSTGYAISAYRLDGFKLATKGYRQFSLLPLRQAVSLNPDNGYLKVLLALKLQDNGQEAEGEKYLEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKIDKMIRLAIFHFESAVENKPTFEVAHLDLARMYIEAGNHRKAEETFQKLLCMKPVVEETMQDIHLQYARFQEFQKKSEINAIIHYLKAIKIEQTSFIRDKSINSLKKLVLKKLQRNALDLESLSLLGFVYKLKGNMNEALEYYERALRLAADFENSVRQGP
What is the function of this protein?
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs.  Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection.  Directly binds PPP-RNA in a non-sequence-specific manner.  Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism) (By similarity).
What are the official names of this protein?
Interferon-induced protein with tetratricopeptide repeats 1, IFIT-1.
What is the protein family that this protein belongs to?
Belongs to the IFIT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_RICB8
Sequence: MQKNLTRWLLTCCIMVVAMIIVGGITRLTDSGLSIVEWRPVTGILPPFSYDTWQAEFAKYKAFPEYNAVNYGMTLSEFKFIYLLEFVHRLLGRATGLIYILPLIYFYFKGIIKNRDILSYIIVLLLFCVQGFMGWYMVKSGLVNHPSVSHFRLAFHLIIAVIIYHLLFYKLVKNCCDILLIPSQINLKLPLIFSVAAIAMIYVQIFLGALVAGLDAGLIYNSFPLMGGNFIPIEIKDNFISFKNWYDPVFVQFMHRLGAYSLSIIVIALIISLLKVKNPKLNKVAFYLSIALLIQLSTGVITLLYHVPIIAASMHQFFAIVLLSVVIWCYSLIKNS
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3SAPF_NAJAT
Sequence: MKTLLLTLAAATIVCLDLGYTLKCNKLIPIASKTCPAGMNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin I-like P-15, Cardiotoxin I-like P-15.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: Y412_MYCPN
Sequence: MFGLKVKDAQKDDQKSSEYLSGEAGSQAGGSTQGTSTTTQRRGSSNENKVKVLQVAMKKKSDSEDNGQIELETNNLANAPIKRGSNNNQQVQLKADDFGTTSSSESGQSGTQGSTPSNPGPWTPWLTTEQIHNDPAKFAASILILYDAPYARNRTAIDRVDHLDPKVMTANYPPSWRTPKWNHHGLWDWKARDVLLQTTGFFNPRRHPEWFDGGQTVADNEKTGFDVDNSENTKQGFQKEADSDKSAPIALPFEAYFANIGNLTWFGQALLVFGICLS
What are the official names of this protein?
Uncharacterized protein MPN_412.
What is the protein family that this protein belongs to?
Belongs to the adhesin P1 family.
Protein: CSG_HALSA
Sequence: MTDTTGKLRAVLLTALMVGSVIGAGVAFTGGAAAANASDLNDYQRFNENTNYTYSTASEDGKTEGSVASGATIFQGEEDVTFRKLDNEKEVSPATLSRTGGSDEGVPLQMPIPEDQSTGSYDSNGPDNDEADFGVTVQSPSVTMLEVRNNADNDVTGGVLNTQQDESSIAVDYNYYAAEDLELTVEDEDGLDVTDEILAADQSGGAYEDGTGNNGPNTLRFDIDPNNVDAGDYTVSVEGVEDLDFGDATESASVTISSSNKASLNLAEDEVVQGANLKYTIENSPEGNYHAVTIDSSDFRDSSSGADAAKVMRSVGDTVDTGLVVDNDSTTEIVDDYENTSISDVDYAYAIVEIDDGNGVGSIETQYLDDSSADIDLYPASDTEDAPDYVNSNEELTNGSALDGVSTDDDTDFDVTQGDITLDNPTGAYVVGSEVDINGTANEGTDDVVLYARDNNDFELVTVDGEKSIEVDSDDTFEEEDITLSDGDKGGDDILGLPGTYRLGIIAKSDAVNSSGGVKDNIDTSDFNQGVSSTSSIRVTDTELTASFETYNGQVADDDNQIDVEGTAPGKDNVAAIIIGSRGKVKFQSISVDSDDTFDEEDIDISELRQGSASAHILSSGRDGKFGEDTANSISDLEDEVGNYTSGSPTGDQIRDRILSNTVDDTASDDLIVTQQFRLVDGLTTIEATEGGEAGGSLTVMGTTNRKADDNTITVELLQGDASIEINSTDEWNSDGQWSVDVPLSNVEPGNYTVEADDGDNTDRQNVEIVEELEEPDQTTVDQPENNQTMTTTMTETTTETTTEMTTTQENTTENGSEGTSDGESGGSIPGFGVGVALVAVLGAALLALRQN
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
Cell surface glycoprotein, S-layer glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the halobacterial S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Cell membrane.
Protein: NORV_ECOL5
Sequence: MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIVYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREIARQWALAPLPQSTVNTVVEEETSAATTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFDELASEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR8_EUGLO
Sequence: MTTIDTISDVITRIRNANILKLDRVELINTKVAIGICHILKDRGFINSFGEFLNSSDRMSNRRFIQKYIIVNLKYKGERRSPCIKELRRISKPGRRVYVGYKNLHKTKGGIELFVLSTSKGLITDYTAREKGIGGELLFSIC
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ATP6_STAAB
Sequence: MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_CHLAB
Sequence: MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEADTVHILSGIYQGKTTGTPIALQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLGGGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQVSIEEYPKYSKEFAQSIYNSPFLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPAAKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPTSSIHKPCGTVTKTGEPTSYVTQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TKT2_ECOLI
Sequence: MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEGISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGSVSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVERHNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQAAEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGLKGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA
What is the function of this protein?
Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate.  Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 2, TK 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: METXA_METVS
Sequence: MKKGSVGNVETKTYALPNELVLKSGKTLKEVNIAYETYGKLNKDKNNAILVFHALSGNAHAAGIHKTDGKLGWWDALIGPLKCIDTNKYFVICSNVLGGCNGTTGPSSINPDTNKPYGIDFPVITISDMVTLQKNLIDHLGIKKLFSIIGGSMGGMQALEWCATYPEVINSAVIIATTSSSSPQQIAFNEIGRRAIMSDPKWDGGKYYYKNQPSEGLALARMIGHVTYLSKDSMHEKFGRCLQDKNEYGFNFETDFQVESYLKYQGDSFTKRFDANSYLYLTKALDYFDLTKNGSLSDAFEKLSAKIMIVSINSDWLYTPEEAKEIVSAMSTSGINVKYHEIKSIYGHDAFLIENGQMSYIISEFLSEKIVENIMTKNFSTIYENETIKKAASLMVSKNITHIPVVSNENKLLGIITAWDVSKSIAEENSIENIKISQMMTKNVITAFIDDKIEKIAIKMQEYNISCLPVVDQNGLVIGMISAENITNTITI
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD1_SALAI
Sequence: MTATLMDGRTLSRQLLESTAERVTGFHRSHGRRPCLATVLVGEDPASHTYVRIKVNRCTEVGIDSRRFDLPTLTTTEQLVRVLRDLSSDSAVDGILLQHPTPPQIDEHAAFEAIDPSKDVDGVTGTSFAAMAFGYRGFASCTPAAIMRLLDAYDVPLSGQRAVVVGRSAILGKPIGMLLLARDATVTYCHSRTTDLAAHVAEADLVVAAVGVPHLVRGEWIKPGAVVVDAGYNAGNVGDVQAATAANRASLITPVPGGVGPMTIAVLLAQTVDAAERHG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BRLF1_EHV2
Sequence: MEPKDFQPEIKPPKPFCIEQFVGCSKEFKEKTLRLITLYHECLINARGGDDFMRYMYDVCLSLEQEMRQYNALAGFLLECNLFNLWNLFRNYKNKQSAESANTNPCALMAQQFLKFHTERLLVCTDRFFSTGCCSQINMPYDLCQHVFKFQQDLRKRCIASWKTLSGGRRAFMTVVQDIFTCFTTLRANELITPRQQAFFKLSYPPCRVQNVINILNVVHTQGIKDLKSLNMQKIKKRTPHAGIFSASGQPLFPIPEALLVDFNGEGIIRSDIADVSPFLQNPEEFLATDFFTYIKRFQGVGVQIRDPEPRYQPASQQPQQALRPQQQVLQQATAYPASVQAGGFAIQTESPMEGTSAQYFLAAQQHGVVGLFPSTATLVPIAGSTGVTEVVSYGHNSTSPVSTFSAPSTSVTEADHQTQPRRSRKATAKRKHQQVQDGNEDEGPQRHPQAHSRQFFQGAASHQTAQPAQVLQQSVIHGTQGALYFMGPAQQIPGDHSQIPVISNAMLQSVLQQQGGSGAAIYDLSQLQPCVVPVQQQAAQEVAVPTAVIHYQPAMQPQPQPYQQQQFLQPQQQAQTPSPQMQQRQLTPQSSPEPADEEEEGPLNLTTRTEDHEILEEILSNLYPEERRQQEQQHQQGEEAAPASPSQHEEQAGPSNQSGETSQELDIFSLHNLHLRKSLFE
What is the function of this protein?
Transcription activation.
What are the official names of this protein?
Putative transcription activator BRLF1 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TAF50 family.
Protein: LMCPB_LEIME
Sequence: MATSRAALCAVAVVCVVLAAACAPARAIHVGTPAAALFEEFKRTYGRAYETLAEEQQRLANFERNLELMREHQARNPHAQFGITKFFDLSEAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPDAVDWREKGAVTPVKDQGACGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDDMNDGCDGGLMLQAFDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSELVVGAQIDGHVLIGSSEKAMAAWLAKNGPIAIALDASSFMSYKSGVLTACIGKQLNHGVLLVGYDMTGEVPYWVIKNSWGGDWGEQGYVRVVMGVNACLLSEYPVSAHVRESAAPGTSTSSETPAPRPVMVEQVICFDKNCTQGCRKTLIKANECHKNGGGGASMIKCSPQKVTMCTYSNEFCVGGGLCFETPDGKCAPYFLGSIMNTCHYT
What are the official names of this protein?
Cysteine proteinase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: OR2L8_HUMAN
Sequence: MENYNQTSTDFILLGLFPPSRIDLFFFILIVFIFLMALIGNLSMILLIFLDTHLHTPMYFLLSQLSLIDLNYISTIVPKMASDFLHGNKSISFTGCGIQSFFFLALGGAEALLLASMAYDRYIAICFPLHYLIRMSKRVCVLMITGSWIIGSINACAHTVYVLHIPYCRSRAINHFFCDVPAMVTLACMDTWVYEGTVFLSATIFLVFPFIGISCSYGQVLFAVYHMKSAEGRKKAYLTCSTHLTVVTFYYAPFVYTYLRPRSLRSPTEDKVLAVFYTILTPMLNPIIYSLRNKEVMGALTRVSQRICSVKM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2L8, Olfactory receptor OR1-46.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YBDF_ECOLI
Sequence: MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSSELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLINDSWNLVVDGLAKRDQKRVRPG
What are the official names of this protein?
Uncharacterized protein YbdF.
Protein: RK21_CHAGL
Sequence: MSTYAIIDLGGKQLRVEPGRFYDAHLFSSFKSLLSESNTKIIIFRVLMISHGTEVQFGYPWLKNASVKARILHKKQNDKMLIYKMRSKKKTRKKFGHRQKIARFIVDAIQYNGQTFTTNLK
What is the function of this protein?
This protein binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L21, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GRIK5_MOUSE
Sequence: MPAELLLLLIVAFANPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAGAHGGPQRLLDDPGPPGGPRPQAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGTPAEATSPPRPRPGPTGPRELTEHE
What is the function of this protein?
Receptor for glutamate.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.  This receptor binds kainate > quisqualate = glutamate >> AMPA.
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 5, GluK5, Glutamate receptor KA-2, KA2, Glutamate receptor gamma-2, GluR gamma-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: HSLV_RICAH
Sequence: MSDNLALHGTTILCLKKNEEIIIAADGQVSHGNTVLKSTARKLRTIANNKIIAGFAGSTADGLALFEKLEVKIEQHKHNLLRSAVELAKDWRNDKYLRRLEAMMIVGDRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSYENNLTAEEIALKSMNIAADLCVFSNHNIIMEKVV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA50A_DANRE
Sequence: MAQYKGAASEAGRAMQLMKKREREREQLEQLKQKIAEDNMVKSNIDKKFSAHYDAVEQELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQLKLEKQKEKKRKEEQKRKIASLSFNPDEGEDEEEEEEEEEEEEEDEIEEEICLPVKKKKLGKNPDVDTSFLPDRDREEEENRLREELRQEWERKQEKIKSEEIEITFSYWDGSGHRKTVKMKKGNTIQQFLQRALEVLRKDFSELRSAGVEHLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDIRLVNDATVEKDESHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
What is the function of this protein?
Probably involved in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Protein FAM50A.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
What are the subcellular locations of this protein?
Nucleus.