PharMolix/UniProtQA huggingface dataset:
Protein: PPE32_MYCTU
Sequence: MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD
What are the official names of this protein?
Uncharacterized PPE family protein PPE32.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: TES_LOXAF
Sequence: MDLEARVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNISINTVTYEWAPPVHNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELTPREVKEMEQFVKKYKNEALGVGDVKLPQEMDTQGPNRIYIPGGDRSTAAAVGAMEDKSAEQKGTQYSCYCCKLSMKEGDPAVYAERAGYDKLWHPACFVCSACSELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: YPZF_BACSU
Sequence: MLGRTKLGNRNAQANNNAKKKNGFQTHFDSYAGREAEKLIASNKRHND
What are the official names of this protein?
Uncharacterized protein YpzF.
Protein: HUTU_BACC7
Sequence: MEKVKQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYNAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALTVANEYKEKKEPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLTMQAKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVETAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTDA_BACSU
Sequence: MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITTLSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIGV
What is the function of this protein?
Involved in the biosynthesis of kanosamine (3-amino-3-deoxy-D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)).  Catalyzes the reversible pyridoxal phosphate-dependent transamination of 3-dehydro-alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate.  It can only use alpha-anomer and glutamate is the only amino donor.
What are the official names of this protein?
3-oxo-glucose-6-phosphate:glutamate aminotransferase, 3-dehydro-glucose-6-phosphate--glutamate transaminase, Kanosamine 6-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: RS14_BURMS
Sequence: MAKLALIEREKKRARLAQKYAPKRAELKAIIDDASKSDEERYAARLELQQLPRNANPTRKRNRCAITGRPRGTFRKFGLARNKIREIAFRGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: EFG_HERA2
Sequence: MPRSTPLDRVRNIGIIAHIDAGKTTTTERILFYTGRNYKIGEVHEGAATMDWMEQERERGITITAAATTAHWEYAEQRYQINIIDTPGHVDFTAEVERSLRVLDGGVVVFDAVAGVEPQSETVWRQADKYNVPRICFVNKMDRMGANFDRTVQMIVDRLGAKPVPIQLPIGAEDRFQGIIDLMENKAIFYMDDVGKVQEEREIPAELAEKAKAAREYMLEAIAETDDELMMLYLEGEELQVPELRRALRAATIGNKLVPVLCGSALKNKGVQRMLDAVVLLLPSPLEIPVTKAVRPGVDSEAEDAEFIERPADENAPFTGLVFKIMADPFVGKLAYFRVYSGKLETGSYVLNTTKNKRERVGRLLQMHANHREEIKEVYAGDIAAVVGPKDTFTGDTICSPDDPVVLESIKFPEPVISVAIEPKTKADQDKMSIALSRLAEEDPTFRLNTDVETGQTIIRGMGELHLEVIVDRMMREFKVEANVGKPQVAYRESITRSVDIDSKFVRQSGGKGQYGHVKVKFEPSGEGEGYIFVNGIVGGVVPREYVPAVEAGIREAMETGVIAGYPVVDVKATLFDGSYHDVDSSEMAFKIAASMALKDGVRKGGPQILEPIMKIEVIVPEDYMGSVIGDVNSRRGRIEGMEARGNAQVVRGFVPLANMFGYVNDLRSQTQGRATYSMEFHHYEPIPRNLQEELVEKARS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_HALH5
Sequence: MKDLPLSIGGKTLTSRFFLGTGRYPNPFVQNEVIRVSEAEVLTFAIRRVNLQAPGEDAILQHLEGKTFTYLPNTSGAKNAEEAIRIARLARASGLSDWIKVEISVNERTLLPDPVETLRATETLANEGFTVLPYTSDDPVLCKRLEEAGAAAVMPGGAPIGTGLGILNPYNLGLIVEEANVPIIVDAGLGSAQDVVQAMELGADGVLMNTPVAKAKDPVKMALAMKHAIEAGRLSYLAGRIPKKRYATASSGLETFISK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
Protein: HRPS_PSESY
Sequence: MNLDDEFDDDLDAERVPNLGIVAESISQLGIDVLLSGETGTGKDTTARRIHNMSGRQGRFVPMNCAAIPESLAESELFGVVSGAYTGADRSRMGYIEAAQGGTLYLDEIDSMPLALQAKLLRVLETRALERLGSTSTIHLDICVIASAQASLDDAVEEGKFRRDLYFRLNVLTLKLPPLRDQPERILPLFTRFVAASAKELNVAIPDVCPLLQQVLTGHRWPGNIRELKAAAKRHVLGFPLLGADSQTEEHMACGLKFQLRAIEKALIQQALKRHRNCIDAASLELDIPRRTLYRRIKELSI
What is the function of this protein?
Regulates the activation of the sigma factor HrpL which itself induces the expression of hprD as well as other hrp loci which are involved in plant pathogenicity, hrmA and avr genes.  Probably interacts with sigma-54.
What are the official names of this protein?
Pathogenicity locus probable regulatory protein HrpS.
Protein: ISPD_MYCLE
Sequence: MAVATGTVVAVVPAAGAGKRLAAGIPKAFCELDGRTLVERAVVGLLESGVVDHVVVAVPADRIAQTQWVLSQRLANSAGQHATVVAGGADRTKSVCQALATLPAPSRVGAPEFILVHDAARALTPARLIVRVVDALRAGHTAVVPALPLSDTIKAVDANGMVLGTPARVGLRAVQTPQGFATELLWCAYQRGPHLDAVDFTDDASLVEHLGGQVQVVAGDPLAFKITTQLDLLLAKKILRR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TUSC_VIBVY
Sequence: MSQLTYLFRTAPHSHSSGREGVDALLAASAYCEALSVVFIGDGVYQLLAGQQTASILCKDYAPMFKLFDLYDIEHVYVCQQSLQQRGLTSEDLLIDVEVVDTVRLQGVLHNSAQLLSF
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Protein TusC homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRSA_ECOL5
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFSHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKVVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: LOLB_XANC5
Sequence: MSRAVRTLALGGLVLVGLSACVSVPRGQGSGAAVADHVSDSARQAEAARQAWLQAHPNWSFQGRVAISKDRNGGSGRIDWQQDGPRYRVQLSAPVTRQSWVLTGDTTSGAGRLEGLDGGPRSGPDAEQVLLEATGWTIPVNQMPDWVRALRIADAGAARVDLDAAGRPRTAQQDGWTIEFLAWTPAGADQPELPQRIEARNGEAKVRLLVDQWTVSP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ILVC_ECO27
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FRMA_ECOLI
Sequence: MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAVAGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
What is the function of this protein?
Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent.  In addition, hemithiolacetals other than those formed from GSH, including omega-thiol fatty acids, also are substrates.
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BBP1_YEAS8
Sequence: MNQEDNTGGGGIFGLFKWTKDALFGTDISPSMKYKDQEERRDRSRYAQDDTNFSMKFGNDSNRRSTNLSRSNSWSGLDSTLHRKYELLPEYNENGFNSIVNGDHHSKERIRSLRSPAPIVPREPLRNEPTDTFGHRLHTKRRTINELSNSQIPFIPPQEDDPLLSKLFNKDGVNEVRRSPYKLSVKDIPGKFPSPLTKRDEIDNYYVRDEDACHKNREYKKAYFDLFAQMDLNSRDLEDLCEDVREQREQFHRNEQTYKQAYEEMRAELVNELKKSKTLFENYYSLGQKYKSLKKVLDQTISHEAELATSRERLYQEEDLKNFEIQTLKQRLSDLELKYTNLQIEKDMQRDNYESEIHDLLLQLSLRNNERKDTSAGSNIFSTGQYDRTPFHNGNNSYDSNSHSWDTDYLKNIDGFIER
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.  Connects the central plaque of the SPB with the half-bridge.  Required for proper localization of CDC5 at the SPB and for proper M-phase progression (By similarity).
What are the official names of this protein?
Spindle pole component BBP1, BFR1-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the BBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associates with the periphary of the central plaque.
Protein: GLGA_THEAB
Sequence: MKVALVSYEVYPFAKVGGLADVVGALPKYLKNFSVEPIVIMPKHKIVEKNAEKFSYSLRKIKESISVPYLKTDEKFDIYQTFIPGTQIPVYLIANDYYFSAEQVYEGPDLAEQAIYFSAAVFEALKVLGEKVDVLHINDWQTGLVPVYLKTLYKDDEFFSKTVVLLTIHNLGYQGIFDSSYMNFSGLPDYLYNIDGIEFYGKINFLKGGILFSDVINTVSPTYAQEIQTKEYGEKLDGVLRLRSSDLYGILNGIDYDEYNPETDKRIYVNYSLQEIEKKYENKKMLQKELNLPQTNDVPVIGMITRLVDQKGLDILSEVLRYILNMDVQFVLLGTGDKKYEEMFKDIEKEFPDKMSANITFDIVLAQKIYASSDMFLMPSRYEPCGLGQMYSLRYGTIPVVRYTGGLADTVMEYDEEAMKGNGFGFKEYDSAYLLKAVARAVDFFKNKKGHWKKLIENAMKTDLSWERSANEYVKIYNKALNKRR
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TDH_FRATM
Sequence: MKALAKLKKQPGIWIINDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPVPMITGHEFAGEVVAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGVNVQGAFAEYLVMPAVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLTGEDVLITGAGPIGLMVVKIARFCGARRIVITDINEYRLQMARDFGATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDVGLEMSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLMTSMLQAGMDMNPIITHRLHIDEFQKGFEIMKSGQCGKVILDWSS
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1389_YERPB
Sequence: MPQSSRYSDEHVEQLLSELVSVLEKHRTPTDLSLMVLGNMVTNLINTSIAPAQRKVLARSFAEALQASVREDKAH
What are the official names of this protein?
UPF0352 protein YPTS_1389.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: T65_TERSU
Sequence: MAINGRLLCLCLVLGLVFESLGHPSVQEKRAAEDSKPSGERRQTLTTKHEVDCGGIPCQFGCCENDKCRELDCEHYPGIP
What are the official names of this protein?
Teretoxin Tsu6.5.
What is the protein family that this protein belongs to?
Belongs to the teretoxin M (TM) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_THET8
Sequence: MRIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAALHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREALRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLLRLPQDRIGLTFKTSEGLAPSHVQARAVVLLDG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SIGS_STAAT
Sequence: MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQIYKPSSKQSLSSFLFTRLNFYLIDLFRQQNQLKDVILCENNSPTLTEQPTYFNEHDLRLQDIFKLLNQRERLWLKLYLEGYKQFEIAEIMSLSLSTIKLIKMSVKRKCQHNFN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival (By similarity).
What are the official names of this protein?
RNA polymerase sigma factor SigS.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: NAGB_LACLA
Sequence: MKVIVVKNQLEGGKIGLDLLKKSMANGAKTLGLATGSTPVEFYNQIVNSDLDFTDMVSVNLDEYVGLDGSNDQSYRYFMTKHLFGEKPFKENFLPNGKAADLEAEAKHYDQIIEENPIDWQILGIGQNGHIGFNEPGTPAEITTHVVDLQESTIKANARFFESEADVPRKAISMGLASIMKSKNIVLMAYGKEKAEAIKGMVEGEVTTELPASILQNHANVTVIADEAAVSLLSK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: DUT_FRATM
Sequence: MKVELKILNKELIKELPGYATEGSAAIDLRACISESIYLKSGECKLVATGIAINIANPNYAAMILPRSGLGHKKGLVLGNGTGLIDSDYQGELMVSCFNRSQETIEIEPLMRFAQLVIVPVVQANFEIVEDFSQQSVRATGGFGHTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: AMTAB_METTH
Sequence: MDGIRVYIETFGCTFNQADSEIMAGVLREEGAVLTGIDDADVIIINTCYVKHPTEHKVINRIKKIQETYPEKGLVVAGCMVEIDPSKLEAISGDASWLGPHQLRRAPQAVRAASNGLVERITGFTSDVKVKVPRVRSNPLIHIIPICEGCNGSCSYCCTRFARGRIQSYPSDLIISEAREAVASGCREIQLTAQDTAAYGVDTGEKLSDIIKGISGIPGNFRIRVGMMHPASVLRDLDGLVEAFKSEKVYSFLHLPVQSGSDSVLADMERGHTVDEFRMIVERFRSEIPDISIATDIIVGYPTEEREDFMDTCSLLEEVKPSFIHLSKYRHRPRARSSSLDEIDFRELRRRSRALEELKMRITEEENRRLVGSFQEILVVERGRKGGFIGRTGSYIPVVTETGEPGSFRRVRIRDATGTYLLAD
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Probable threonylcarbamoyladenosine tRNA methylthiotransferase, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Protein: KRA51_MOUSE
Sequence: MTCCGCSGGCGSSCGGCGSSCGGCGSGCGGCGSNCGGCGSSCCKPVCCCKPVCCCVPVCSCSSCGGCGSSCGGCGSCGSSCGGCGSSCCKPVCCCVPVCSCSSCGGCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQDSC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-1, Ultra high sulfur serine protein 1, UHS-Ser-1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: Y787_TREPA
Sequence: MHCPLLRHTVVIEWAAPSMVGSAPMGRDSPAGMREAVYFLHRMVVCLGVLLCAASLLYVFGNFSHFLDKSQFIILRSCVGCSVLLVVACLCAGSFELYFFLTRSDAPYGRLLCITVVALLFGMGALVFNTVVLIVAKGT
What are the official names of this protein?
Uncharacterized protein TP_0787.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NPHP3_MOUSE
Sequence: MGTASSLVSPTGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWASRALGSEHSIGSMIQLPQPFRGPEFAHSSIDVEGPFANINRDDWDAAVAGLLQATPLFSHSLWSHPVRCYLIYTDETQPEMELFLKDHSPKLKRMCETMGYFFLAVYFPLDVENQYLTVRKWEIEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPGLIYHRLEDGKVTCDSVQQFLDQVSNLGKTTKAKIIEHSGDPAEGVCKIYVGVEKIIKQDILGLENTDVEEKDGGREDSTPEEDDFGDVLWDIHDEQEQMEAFQQTSSSAHELGFEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKHFPNTLILSHFVGRPMSTSSESSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSIIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPTAWRLWPTLHLDPLSPKDAISIITAECYSMDVRLSREQEKMLEQHCRPATTRHALYVTLFSKMMACAGRGGNVAETLHQCLQCQDTVSLYKLVLHHVRESMPSDRDKEWMTQILCLINVSHNGVSESELMELYPEMSWLSLTSIVHSLHKMHLLTYSCGLLRFQHLQAWETVRLQYLEDPALVSSYREKLISYFASQLSQDRVTWRSADELPWLFQQQGSKQKLHSCLLNLLVAQNLYKRGHFAELLSYWQFVGKDKGAMATEYFESLKQYENSEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLAGVYVQWKKFGDAEQLYKQALEISENAYGADHPHAARELEALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYFLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGKVDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGNFEKAAELYKRAMEIKEAETSLLGGKAPSRQSSSGDTFLFKTTHSPNVFLPQGQS
What is the function of this protein?
Required for normal ciliary development and function.  Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling that regulates planar cell polarity.  Probably acts as a molecular switch between different Wnt signaling pathways.  Required for proper convergent extension cell movements.
What are the official names of this protein?
Nephrocystin-3.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Localization to cilium is mediated via interaction with UNC119 and UNC119B, which bind to the myristoyl moiety of the N-terminus.
Protein: Y5795_DICDI
Sequence: MSSVRAQFAEVQEQLNQVHSLVDSNTPSDLNKAATILKSLLPVYKDLSGNEESKRPENLEILKEIKSRLTEETQRVMSKKEEAKSLQIQQQQQQQQLLQQQQQQQILESTTRNRQASQQELPKPPILSGYLKKQGDKGLVRSFKKRWFLQRDTKLFYYEKEGDSEPYGFVNLPEMINVKTVDSGFELATPSRVYVFQVFKPSDLTYWTEGLKEFKKYYQSLQNSQKFGANANGNGNSSPNMSSSGSYSDFRKYSESSQQPLNSSTGAINTTPQRGTPIKDRRGTVSGGTTEYSHSSSSTAPDSPTLSSSYVPPPSSSNLNPQDEELKRRENEIIRKHQEKLKQQDDQQQDDKQQQQQQSQEPPQQQQQQQEQLQSQPSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPPQTSPQNSRHGSTNYSQLQQQQQQPQQQPQQQSSPQVIISNNNSPRFESQQQQNNFHNNGSNINLESFRQSIEDELNKKFLKEKQDLMEFEIKKRLEIESEIKKLQLQLDQTKTDAEEKQNKSSNELKKKKAEIEDYEARVTIITKRNEEMDAKIKELESSRPVETFPHEFLWTEEVNSRDLLIASQSKRILELEEQLKLKDNAVTVIKRENEMLRQETEKKDKYINELLEKGGGSGIHTNSNNNNNSNNNNNNSNNNSNTDKIKESMVAHQTQNAFLLQEIQRLETQSQFKLDIKIQQIEELENQLEQQLYQFHRFREAIIGTMSNEYCVKIEKENLDVKKEYFQSLGVSIKLHRVKEGYFANIDINSLFDKVIKENVHYRNWPEWISNQFNQA
What are the official names of this protein?
PH domain-containing protein DDB_G0275795.