PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_CHLVU
Sequence: MPIGVPKVPFRLPGEPSAQWVDLYNRLYRERVLFLCQELDDELANQLIGIMLYLNAEEQNKGLYIYINSPGGSVTCGIAVYDAMNYIKSEVTTICVGTAASMASFILAGGDRGKRIALPHSRIMVHQPEGGSQGQASEVLSESQEVMRIRRQVGRIYSERTGQTLSRVSRDMDRDQFLSAREAKEYGLVDQVAVDTKWSTN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SPAC7_MOUSE
Sequence: MAANRGSRTFLSVFLLCCWQGAELQPIKTTSGPITEGSLNSTTENIPEALDEILAQEILEPKTSAVSETSPRPRSSILTTVQTKEINAGIDENYQEEAFENYHEVLENIEHLPTKEESGKNDRSTVANLHDHSSQTKHEPPSSPEGKGSSNDDVYGKLSVLDKILENIGQSEGSLELTESIF
What is the function of this protein?
Involved in fertilization.  Seems not to play a direct role in sperm-egg binding or gamete fusion.
What are the official names of this protein?
Sperm acrosome-associated protein 7.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome lumen. Note=Localized in perinuclear pro-acrosomal granules in round spermatides (PubMed:24307706). Localized between the inner and outer acrosomal membranes (matrix or lumen) in spermatozoa (PubMed:24307706). Secreted during acrosome exocytosis (PubMed:24307706).
Protein: DEUP1_XENTR
Sequence: MFTNIHSIARNSSCENELEELMHQIDIMVSHRKVEWEKHVKVLEQKLEAQDRELTEARNLVDEKNHEIGILCKKLEGVDTAQHEMAQNYERQLQALKFQLCKLKKSYEKLHFHQEKHQKNENAAQERSRCELQWLTQKIEEFKARSREWEKQRVFYQDQLKSLDEQRKTLAEKCQLFQKESLSYQEQLSSQKQLQSEAITNNQSEMRRLRCLLDTSQETIRSDGVIIENLKSTVKEITLSRDSLKDENQQLLQELRRCQKQSQNMEAQLYKAKLELQSCNDLLRVPALEERQAQKETANLANQKTAQGEEASFQVTDPRMNYMTSEPEHKSFNLSKSEKYQAENDLHGTEAKNSDLERLRKDIGDLTAKLNQKDVTIATVSRKVSRLERELELKGAQNRQTSMPLSQKDVIAELESEMPQIHAVNKAPQTDSGEVDPWISIKCGEHDKPQKHRSFHGENNSLKPTNYADTRNHSVGSEWESEKSLCPWNTPTLGSATDDDCDLVDNENEWLSLYNSTLYPGLDLPPISYACDQLKDSTNSSLAGSSLISAAEKFLLEETRRASDFEKILNSHIEEMKRNSESTVSRYQSHGQSRHI
What is the function of this protein?
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles.  Probably sufficient for the specification and formation of the deuterosome inner core.
What are the official names of this protein?
Deuterosome assembly protein 1, Coiled-coil domain-containing protein 67.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the deuterosome.
Protein: RL28A_MYCBO
Sequence: MSARCQITGRTVGFGKAVSHSHRRTRRRWPPNIQLKAYYLPSEDRRIKVRVSAQGIKVIDRDGHRGRRRAARAGSAPAHFARQAGSSLRTAAIL
What are the official names of this protein?
50S ribosomal protein L28-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: APBLB_ARATH
Sequence: MSGHDSKYFSTTKKGEIPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVNCMQTENLELKKLVYLYLINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEYLCDPLQKCLKDDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKDLISDNNPMVVANAVAALAEIQENSSSPIFEINSTTLTKLLTALNECTEWGQVFILDALSKYKAADPREAENIVERVTPRLQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPEIQYVALRNINLIVQKRPTILAHEIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVLLEFKEYATEVDVDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKDIFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAERIDNADELLESFLENFPEEPAQVQLQLLTATVKLFLKKPTEGPQQMIQVVLNNATVETDNPDLRDRAYIYWRLLSTDPEAAKDVVLAEKPVISDDSNQLDPSLLDELLTNISTLSSVYHKPPEAFVTRLKTTVQKTEDEDFAEGSEAGYSSSNPVDSAASPPGNIPQPSGRQPAPAVPAPVPDLLGDLMGLDNAAIVPVDDPITQSGPPLPVVVPASSGQGLQISAQLSRKDGQVFYSMLFENNSQSVLDGFMIQFNKNTFGLAAAGSLQIPPLHPATSARTMLPMVLFQNMSAGPPSSLLQVAVKNNQQPVWYFTDKIILHALFGEDGRMERGTFLETWRSLPDSNEVLKEFPGITITSVESTIELLTAFNMFFIAKRKNGNQDVIYLSAKDPRDVPFLIELTAMVGQPGLKCAVKTPTPEIAPLFFEALELLFKA
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).
What are the official names of this protein?
Beta-adaptin-like protein B, At-bB-Ad, At-betaB-Ad, AP complex subunit beta-B, Adaptor protein complex AP subunit beta-B, Beta-adaptin B, Clathrin assembly protein complex beta large chain B.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the trans-Golgi network. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (By similarity).
Protein: GPXA_NEIMF
Sequence: MGIYDFQMKDAEGNAVDLSGYRGKVLLIVNTATRCGLTPQYEALQKLYAQYTAEGLEILDFPCNQFREQAPESSGEIAQVCMMKFGTKFKIFDKIEVNGANTAPLYAYLKSVKPQDKGNHLFKDFVLKLAALGEKRDEGDIKWNFTKFLVNRDGEVVERFAPSVTPEEIEADIRALL
What is the function of this protein?
Important in the cellular metabolism or defense processes particular to this pathogen.
What are the official names of this protein?
Glutathione peroxidase homolog.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: RS13_STRSY
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVRVKDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: C7344_ORYSJ
Sequence: MMEAVAVAAAVLLLLHVAARVADAVWWRPRRLEAHFAGQGVRGPPYRFLVGCVREMVALMAEATAKPMPPAAPHNALPRVLAFYHYWRKIYGPTFLIWFGPTPRLTVAEPEMVREIFLTRAEAFDRYEAHPVVRQLEGDGLVSLHGDKWAHHRRVLTPGFYPDNLNRLVPHVGRSVAALAERWRAMACAGGGEVEVDVAEWFQAVAEEAITRATFGRSYDSGRVVFRLQARLMAFASEAFRKVLVPGYRFLPTKKNRMSWGLDREIRRGLVRLIGRRSGGDGGEEDETTTELKDKQDSGFNDLLGLMINAGVDRTMPVEDMVEECKTFFFAGKQTTTNLLTWATVLLAMHPDWQDRARREVLAVCGDAAGELPTKDHLPKLKTLGMILNETLRLYPPAVATIRRAKFDVTLGGGGDGDAGGIHIPRDTELLVPIMAIHHDARLWGPDAAQFNPARFASGAARAAKHPLAFIPFGLGSRMCIGQSLAILEAKLTMAVLLQRFDLALSPTYVHAPTVLMLLHPQYGAPLIFRPRQSQPSN
What is the function of this protein?
Cytochrome P450 involved in brassinosteroids (BRs) inactivation and regulation of BRs homeostasis.  Is a multifunctional and multisubstrate enzyme that controls the endogenous bioactive BR content both by direct inactivation of castasterone (CS) and by decreasing the levels of BR precursors.  Catalyzes the oxidation of carbon 22 hydroxylated BR intermediates to produce C26 oxidized metabolites.
What are the official names of this protein?
Cytochrome P450 734A4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYP_PSEE4
Sequence: MRTSQYLLATQKETPADAVVISHQLMLRAGMIRKLASGLYTWLPMGLRVMRKVEAVVREEMNAAGALEVLMPSIQPAELWQESGRWEQYGPELLRLKDRHDRDFCVGPTHEEVITDLARNELSSYKQLPLNMYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHADQASLQETYDRMHQAYSNIFTRLGLDFRPVQADTGSIGGSYSHEFHVLASSGEDDVIFSDSSDYAANIEKAEAIPRETVRPAPTEELRLVDTPNAKTIAELVENFGLAIEKTVKTLIVHGAEEGKLVALIVRGDHELNEIKAAKLEQVADPLVMASDTELRAAIGAGAGSLGPLNLPLECIIDRSVALMSDFGIGANIDDKHYFGVNWERDLPVPQVADLRNVVEGDPSPDGQGTLVIKRGIEVGHIFQLGTKYSEALKCQVLGENGKPVVLSMGCYGIGVSRVVAAAIEQSYDDKGIIWNDALAPFQIALVPLRYETDVVREATDKLYAELTAAGFEVLLDDRDKKTSPGIKFADMELIGIPHRIVVSDRGLADGNLEYKHRTESEAQALPLNEVLTFLQARIRR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMC9_MOUSE
Sequence: MGEVEISARAYGKMCLHASRYPHAAVNGLLLAPATGSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAVLDDQSPGPLALKIAGRIAEFFPRAVLIMLDNKKLVTRPRVPPVIVLENQGLQWVPKDKNLVMWRDWEESRQMVGALLEGRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWSGSTDGNA
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 9, Protein FAM158A.
What is the protein family that this protein belongs to?
Belongs to the EMC8/EMC9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PNP_FERNB
Sequence: MKEWRKNLFGREWLFQHGKVAKQSAGSIWARFGDSVVLATVNVSDNVVEGIDFVPLTVEFMEKFYAAGKIPGGFVKREGKPSESGILSSRLIDRPIRPLFPKNLRNEVQVIVTVLSVDPNCPTDVLGITAASLALNISRVPFDGIVAGVQIGYVDGQFIVFPTAEQLERSKIDIVVAGTKDAITMVEGEAKEVTEEEMLQALMTAHEAIKQIVAFQEEVIKEFNVEKMPLPEPKYNVELVEKFVEYIDMTELEKRIFARGKQERAEMADEYYESIVQKFFEDNNIPEEEQEEYAIPLKEKYDEISKKLMRKIIIERGLRADGRGPKDIRPITCEVGLLPRTHGSSLFTRGETQSLGIVTLGSPAEEQIIDTLIEEGTKRFILHYNFPPFSTGEVKPLRGPSRREIGHGHLAERAVKAIIPPEDEFPYVIRVVSEILESNGSSSMATVCSASLALMDAGVPTKKHVAGVAMGLILEEGKGVILTDIIGLEDHWGDMDFKVAGTKDGITAFQMDCKVSGVSEELLRQALYQAKEARMFILDKLYETISEPRKELSPYAPRISWFFIDPTRSGELIGPGGKTIKSIIKMFDVEISLDDSTGKVTVSGVDAEKVQEAVEYIQNMFRDISIGDLYTGKVTRVENYGIFVEIMPGKIGLVHSSKLGNVKPTSFKVGDKIKVEVINIDDAGRLQFRRLEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTGIS_HUMAN
Sequence: MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP
What is the function of this protein?
Catalyzes the biosynthesis and metabolism of eicosanoids.  Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation (PubMed:18032380, PubMed:25623425, PubMed:12372404, PubMed:15115769).  Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) (PubMed:17459323).
What are the official names of this protein?
Prostacyclin synthase, Hydroperoxy icosatetraenoate dehydratase, Prostaglandin I2 synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ISPG_TRIV2
Sequence: MQTLPTPTTSSNTANQSTFDTTIKRRKTRPVKVGNVTIGGGYPVVVQSMINEDTLDIDGSVAAIRRLHEIGCEIVRVTVPSIAHAVALAEIKQKLITTYQDVPIVADVHHNGMKIALEVAKHIEKVRINPGLYVFEKPNTNRTEYTQAEFEEIGEKIRETLAPLVITLRDQGKAMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICESLDFRNIVISMKASRVPVMVAAYRLMAKRMDDLGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEEVLHKVRESTKHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGYISLYRGREEIKKVPEDKGVEELINLIKADGRWVDP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: COX10_EMENI
Sequence: MILRSSLGRLGVARESPLCLQCLNRSRPSFPAVNKLASISRLQSTVAGQSPSSSVNKTYFSSHKGDSHLTPQPSLFTSLSPSNSPSQLNRGHSTPSTSPELSELPHRRRKRLKEAAAQNNGAEPVIPPDASAQLSNFSSTLPKTSLRRKLAAFFALTKPRLSFLVLLSTTSAYGIYPVSSILALDPTIAPLPTLSTSTLTFLYLTTGTFLSACSANTLNMIFEPKYDAQMSRTRNRPLVRGLVTRRAAVFFAIATAAVGLGLLYFGTNPTVTGLSAANIALYAFVYTPLKRMHVINTWIGAIVGGIPPMMGWVAAAGQGATTGHDTWRDMLFGENSLGGWLLGGILFAWQFPHFNALSHTIREEYKGAGYKMLCWTNPARNARVALRYSVLMFPLSIGLWWAGIVGHGFLVSSTVANGWLTKEAYGFWKHQGANGTARGLFWASIWQLPILLVGALVTKKGLWDGVWGGIFGQPIEDDDDDYVYYEEVSPGKTINQSPTSPSSPVV
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: Y193_RICPR
Sequence: MYITCPNCKTQFIVTSNQIGINGRRVKCSKCKHLWYQKLDYNTSKLNDFKDKINTEAIKTPIKNHYNTNVPVILPLKKKYKIFPILWSSFIIFCLVILLIDSFKFLGKYDQLKIEEINIGKYRNMGGMKIFYKLSNESDYLITNPIIKVRVIDANHHTLGEYASITKLRTKIYAKQAIYLELNIEKIPVTAKYIDITICNRLGLLFK
What are the official names of this protein?
Uncharacterized protein RP193.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL9_BURA4
Sequence: MQIILLEKVANLGNLGDIVKVKDGYARNFLIPNRKARRATKEAIAEFEVRRAELEKVAAEKLAASQAVGEKLNGQSFEITQKSGVDGRLFGSVTNGDIAELLKKAGYEVEKLQVRMPEGPLKMIGEHTVQVALHTDVVVDVTINVIGDHA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NUSB_BRUA4
Sequence: MNSSTEGRPTPNLPRTANKRGVARLAAVQALYQMDVAGTGVLEVVAEYEAFRLGKEVDGTQYLDADPQWFRAIVAGVVDEQLKLDPMIHQALTEDWPLSRLDSTLRAILRAGAWELQTRKDVPTAVIVSEYVDIAKAFYTEDEPKLVNAVLDRLAFVIRGESRGVKPR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HISXH_COLP3
Sequence: MTHKVKIHRLSDLSAEQRNKLLQRTESNLDNFIDIVKPIIENVKLNGDKALSEYAKKFDKAEVSTDQIQVTQAEFDEAFTLVDEEVIQTLSYSIDNIKKFHEAQMPEEMWMKQIRPGCYAGDRFTPINAVACYIPRGKGSFPSVAIMTAVPAIVAGVPTAIIITPPGTDGKVDAATLVVAKLVGIDKVFKCGGAQGIAAVAYGTNTVPKCDKVVGPGSPFVVAAKKLLADIIHPGTPAGPSEAIVLADDTANPKLAALDLLVEAEHGPDSSAFLVTNSKELAEQAQVAINEYWQHMDRLRVDFSSTVLSGDNGGIVLTSTFEEAVDFCNDYAAEHLLILSKSPFDHLGKIINAGEILLGENTPISIANYTLGPNAVLPTSMAAKTASPLSVFDYLKSCSIGYLTREGYEELAPHTYRFAKYEGFDAHANAVSHLRDEAIKSEKKIK
What are the official names of this protein?
Histidinol dehydrogenase homolog.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: FRSA_SERP5
Sequence: MAQANLSEILFKPSFKHPETSTLVLRARSKISAELHSTLEGNTVSNWYRMLNPLLWAWRGVDPIEINEVLARIAVADVEHTNDKWLDTVVGYRNGNWIYEWVHQGMLWQQRALEQQDPLTGGQYWLNAANFYSIAGYPHLKGDELAEQAEALSNRAYEEAALLLPYQLKELEFRIEGGSSITGFLHLPEKGEAPFPTVLMCGSLDTLQTDYHRLFRDYLAPHGIAMLTIDMPSIGSSYKWKLTQDSSFLHQQVLTQLTTVPWIDHQRVTAFGFRFGANVAVRLAYLEPQRLRGVACLGPVVHRLLCDSSTQKHVPDMYMDVLASRMGMANASDHVLKVELNSYSLKTQGLLGRRCPTPMLAGYWEQDPLSPKEESQLIVSSSMDGKLIAIPRKPVYSSFHKALLQMSHWMKDKMR
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: GATC_TREPA
Sequence: MAQQRITSDIFAQLLTLSHLESSECAVGLATQIEDIIQYFSVVEQFDPGPRDDPDTDNAQGRCSQGNKIDVDCCPDWVRKDVALPGLSVHDLKRLSTEFADGYFRAPRALDGSA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RS16_PIG
Sequence: MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NUSG_ECO57
Sequence: MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVSVSIFGRATPVELDFSQVEKA
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.  In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing.  In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho.  May be required to overcome a kinetic limitation of Rho to function at certain terminators.  Also involved in ribosomal RNA transcriptional antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: MOT4_HUMAN
Sequence: MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
What is the function of this protein?
Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate (PubMed:11101640, PubMed:23935841, PubMed:31719150).  Plays a predominant role in L-lactate efflux from highly glycolytic cells (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 4, MCT 4, Solute carrier family 16 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Plasma membrane localization is dependent upon the BSG/MCT4 interaction (PubMed:10921872). Basolateral sorting signals (BLSS) in C-terminal cytoplasmic tail ensure its basolateral expression in polarised epithelial cells (PubMed:21199217).
Protein: SCX3_ANDMA
Sequence: GRDGYIVDTKNCVYHCYPPCDGLCKKNQAKSGSCGFLYPSGLACWCVALPENVPIKDPNDDCHK
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Alpha-toxin Amm3, Amm III.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYN_PECAS
Sequence: MSVVPVVDVLQGRVAVDSEVTVRGWVRTRRDSKAGISFIAVYDGSCFNPLQAVVNNNLSNYQDDVLRLTTGCSVEITGNVVASPGEGQSFELQATNVNVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFHENGYFWVSTPLITASDTEGAGEMFRVSTLDMENLPRTEQGKVDFSKDFFGKEAFLTVSGQLNGETYACALSNVYTFGPTFRAENSNTARHLAEFWMIEPEVAFASLDDVAALAENLLKYVFQAVLNERADDMAFFAERVDKEAVTRLEKFVSSDFAQVDYTDAVEILLNCGQQFENPVYWGVDLSSEHERYLAEQHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERLAALDSRLEEMGLNKEDYWWYRDLRRYGTIPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.