PharMolix/UniProtQA huggingface dataset:
Protein: ARNA_YERPE
Sequence: MKAIVFAYHDIGCVGLNALAEAGYDIQAVFTHTDNPGENRFFSSVARVAADLALPVFAPEDVNHPLWVERIRELQPDIIFSFYYRNMLSDEILSLAPQGGFNLHGSLLPQYRGRAPINWVLVNGETETGVTLHQMVKKADAGPIAGQYKVAISDVDTALTLHAKMRDAAQELLRNLLPRMKEGPLPLTPQKEADASYFGRRTAADGEIHWQKSAFTINNLVRAVTEPYPGAFSYLGQRKLTIWRSRPLDLVHNKLPGTVLSTAPLTVACGEGALEIITGQGEAGLYVQGDRLAQEMGIVTDVRLGNKPSNTLKRRTRVLILGVNGFIGNHLTERLLQDDRYEVYGLDIGSDAISRFLGNPAFHFVEGDISIHSEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGVKEGLKFTLFRPFNWMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRIIENRDGCCDGRIINIGNPTNEASIRELAEMLLTSFENHELRDHFPPFAGFKDIESSAYYGKGYQDVEYRTPSIKNARRILHWQPEIAMQQTVTETLDFFLRAAVIEKTAAPKDELNA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: GLSA_METC4
Sequence: MPDLESIVKDIAAEMRARPDRGAVASYIPELARVDAQGFGLVVIDGEGRVAAGGDADTPFSIQSISKVFTLTLALGMVGDRLWRRVGREPSGSPFNSIVQLEREHGIPRNPFINAGAIAVTDLILSGHQPREALGEILRFMQFVAQDDSITIDERVAASEKRTGFRNAALANYMRSFDVIENPVDYTLGVYFHHCAIAMTCRQLATAGLFLAYSGHHPLAGHSVISAERARRINAIMLTCGHYDGSGDFAYRVGLPGKSGVGGGILAVAPGKASICVWSPGLDAAGNSHLGRIALEMLVKRTGWSIFGV
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: NOP16_ASPNC
Sequence: MVNIRQAKKKRSSLPKAKAKRSGLLKSGKKKINVLGNAIIAENWDRKQTLTQNYRRLGLVHRLNAPSGGSQKRATVNGIEGEPEDSLYIKSSTEALAKQTATSDIKVERDPETGKILRVIRGAADEEVEIAGRKVKRNNPLNDPLNDLSNHGIVTQPRQNASGNAIVEQLERQAAQEGVSVRAKKPRHQSQREEEWVTRLIEKHGDNYAAMARDRRLNPMQQTEGDLKRRIRKFQQSRS
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BOP1_CULQU
Sequence: MVANKSKATKRKVAAAPQPPTAQDKPATNGRSTKQPEADSDQSASDYYESDEENLLANINNDDGDSSDSEGEGDASDGEVQGLNIESDSDFEEDDQEADGEEEEEDSADDVNSDSSPEEDEGESEEEEEDDDEGDLEFEEDLAEPEKPRAIKEGSKAGKKQAPEVESEEEDDLETKKLLEAAAKEDEKLAALDSVLGPDGEKKTRGVGSFPPERKTGRLKNSDEYAGGDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDGNRLIKPPKMDTIDEFLKRMEDPNFWRTVKDPQTGQNVVLSDEDVGLIKRIMAGRNPDQQYNDYEPWIEWFTSEVEKMPIRNIPDHKRSFLPSKSEKQKIGRLVHALKMGWVKTRAETERLAAAAKGPKFYMVWDSDHGKEDIRRIHDHVVAPKRPLPGHAESYNPPPEYLFNERELAEWNSHEEEPWRRKLHYIPQKFNSLREVPYYAQYVRERFLRCLDLYLCPRGKRTRVTVGPEYLIPKLPSPKDLQPFPTLQNLVYRGHTDMIRTISIEPKGEYLVTGSDDKTIKIWEVSTARCIKTIPTGDVVRSVAWCPNVKISLIAVASGKRTLLINPHVGDCLLSKKTDDLLAEAPKHEVVDNERISTAVQWVDVAEEEQKAGVRIVINHFREIKQVTWHGRGDYFATVMPEAQNRSVLIHQLSKRRSQFPFSKSKGLIQCVLFHPVKPCLFVATQRHIRVYDLVKQELLKKLFPSCKWISSMAIHPKGDNLLVATYEKKMMWFDLDLSTRPYQQLKLHFSAIRNVAFHQRYPLFASASDDRSVIVSHGMVYNDLMQNALIVPLRRLENHERVNDFGAFDVVFHPTQPWLFSSGADNTVRLYT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: TRPC_BORPA
Sequence: MNDILAKILAVKAEEVATARQMRSEAELLREAQARQDVRGFAQAIEDKISQGKAGVIAEIKKASPSKGVLRENFDPAEIAASYAMHGAACLSVLTDVQFFQGSHDNLRRARAACSLPVLRKDFIIDPYQIISARAMGADCVLLIVAALAPAQLRDLETLAIDLGMDVLVEVHDAKELDAALALRTPLIGINNRNLRTFETTLQTTLDLLPMIPAGKRVVTESGILKPEDVRLMREHDVQAFLVGEAFMRANDPGVELARLVA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TIG_BURCJ
Sequence: MANVVENLGKLERRVTISLPKDTVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYSGQVEAEVLSDKIGQEFFTISRAENLRVAGQPSFEPKQEQAEDAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEAGEHGDGGADTAAKNGDRVTVDFVGKIDDVAFQGGTAEDFPFVLGEGRMLPEFETAALGLKVGEQRTFDLKFPDDYHGKDVAGKTAQFTVTMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFAEQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASASAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RR18_ORYSJ
Sequence: MYTSKQPFHKSKQTFHKSKQTFRKSKQTFRKFKQPFRKPKQPFRRRPRIGPGDRIDYRNMSLINRFISEQGKILSRRINRLTLKQQRLITLAIKQARILSFLPFRNYENEKQFQAQSISIITGPRPRKNRHIPPLTQKFNSNRNLRNSNQTLRNNNRNLSSDC
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPB_PECCP
Sequence: MKNSSIRIAVVGAGGRMGRQLIQAIEQMDGVVLGAALERSGSSLIGSDAGELAGLGKSGITVKESLNAVQNDFDILIDFTRPEGTLAHLAFCHQHRKGMIIGTTGFDDAGKAAIKQAAQDIGIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIADALGRDLKSCAVYAREGHTGERDPKSIGFATVRAGDIVGEHTAMFADIGERVEITHKASSRMTFANGAVRAAIWISSKENGLFDMRDVLSLDDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATD_SULIM
Sequence: MQENYKAKAYDILKNLNIEEGDLIEIKKGDLRIRGILLPSYSKDERIFVIKLDNGYNIGISIDNISEIKLITKNSSKAQESERKEVSRNGAKSEIKIISTGGTIVSKVEYETGAVRPALTTEEIVQFLPEINEIAKVDAEVLFSILSENMKPEYWVKIAESVKKAFDEGNTGVVIAHGTDTMAYTASALAFSLRSLQGPVVLVGSQRSSDRPSSDSAINLLSAVTTAKYAPFGEVVVNMHADSSDTYALVHRGVKVRKMHSSRRDAFQSVNDKPLAKVLWKERKLVMLDKSYMSKKGETTLDAKFDNRAFLLYYYPGLDRDFLEHILTNTKIRGLIIAGTGLGHTSSDYVELFRKATKDGIFIGMTTQCLFGRVNMNVYTTGRQLLDAGVTPLEDMLPEVALVKLMWVLAHEQDLEKIRSLMISNLVGEINPRHTLDLFPRWSYE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: RPOA_CHLAT
Sequence: MAHQRIVGPTIECIESRIESRRNHYGRFVIAPLEIGQGITVGNVFRRVLLGDLEGACITSVQIPGVNHEFSTIHGVREAVLDILLNLKEIVLKTQSQETQRGHLSVQGPSTVLARDLQLPSSIELVDPDQYIATISGRVSLNMEFTVEVGKGYQLPDYEKKKTFQVDVLPIDAVFMPVTKVNYTVEENYGGDRSQERVIIEVWTNGSINSRQAIDLSVNKIINLFSPLQNVRSIEHEPLVKEKDSKMTEVLVEELDLSVRAYNCLKRAQIHTVSDLLSYSQEDLLEIKNFGRRSAEEVIEGLQKRLGIHLPKEKFTKD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GNAS_DROPS
Sequence: MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSETEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPSDAIMESNDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
What are the official names of this protein?
Guanine nucleotide-binding protein G(s) subunit alpha, Adenylate cyclase-stimulating G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
Protein: RL23_SYNPW
Sequence: MTERFTGRLADVIRRPLITEKATRALELNQYTFEVDHRAAKPDIKAAVEQLFDVKVTGISTMNPPRRSRRVGRFAGKRAQVKKAVVRLAEGSSIQLFPES
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TARS_KALDA
Sequence: MSFVWVEESKECSEQRKGSMWKLKIAQGGKDPYLYSTNNYVGRQTWEFDPEAGTPEERAEVEAARLNFYNNRYRVKPSADLLYRMQFLKEKNFKQTIPPVKVEDGEEITYETATTALKRAVHFYSALQASDGHWPAENSGPLFFLPPLVMCLYITGHLNTVFPAEHQREILRYIYYHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGLDNAVARGRKWILDHGTVTAMPSWGKTWLSIMGLFDWSGSNPMPPEFWLLPSFLPMYPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYDQPYEQVNWKQVRHECAKEDIYYPHPKIQDLLWDTLYIAIEPLLTRWPFNKLVRERALQRTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARVPDYIWVAEDGMKMQSFGSQQWDTGFAIQALLASNMSDEIGETLAKGHDFVKKSQVKDNPSGDFKSMHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSLMPPELVGEKMEPERLYDSVNILLSLQSKNGGLAAWEPAGAPEWLELLNPTEFFADIVIEHEYVECTASAIQALVLFKKLYPGHRKKDIETFIKGAAQYIEDRQMPDGSWYGSWGVCFTYGTWFALGGLAAAGKNYDNCAAIRKGTEFLLNTQCENGGWGESYRSCPEKRYVPLEENKSNLVHTAWALMGLIHSRQAERDITPLHRAAKLLINSQLENGDFPQQEITGVFMKNCMQHYAAYRNIYPLWGIAEYRKQIPLPLR
What is the function of this protein?
Oxidosqualene cyclase that generates taraxerol, a triterpenoid product.  Taraxerol is probably required to coat the leaf exterior as a defense compound against pathogens or herbivores.
What are the official names of this protein?
Taraxerol synthase, KdTAS.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: ARGA_VIBVU
Sequence: MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVLVYGARPQINQLLDKQSSQTPYHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPMAGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAINRSLDQGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDVDPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQVRQACIDDIGGILELIRPLEEQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYIDEHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQIFVLTTHSVHWFREQGFYEIGVDSLPMAKKSLYNYQRRSKILALPL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_NASOF
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AMPP1_AJEDR
Sequence: MGPVDTSQRLARLRELMQERKVDVYIVPSEDSHQSEYIAPCDGRREFISGFTGSAGCAIVSMSKAALSTDGRYFNQAAKQLDNNWMLLKRGFENMPTWQEWTAEQAEGGKVVGVDPSLITASEARSLSETIEKSGGSLQGVQENLIDLVWGKERPARPSEKVALHPIEFAGKSFEEKISDLRKELQKKKSAGFVISMLDEIAWLFNLRGNDIPYNPVFFAYAIITPTTADLYIDDEKLPAEVKKYLGDQVSVKPYGSIFEDAKALSQSAQKKSDGDASTSPSEKFLISTKASWSLSLALGGEKNVEEVRSPITDAKAIKNEAELEGMRACHIRDGAALTEYFAWLENELVNKKTVLNEVDGSDKLEQIRSKHKHFVGLSFDTISSTGPNAAVIHYKAERDTCSIIDPKAVYLCDSGAQYLDGTTDTTRTLHFGEPTEMERKAYTLVLKGLISIDTAVFPKGTTGFALDAFARQHLWKEGLDYLHGTGHGVGSYLNVHEGPIGLGTRVQYAEVAITPGNVISDEPGFYEDGVFGIRIENIIIAKEVKTTHGFGEKPWLGFEHVTMTPLCQKLINPSLLTDGEKKWVNDYHSKVWEKTSSYFENDELTRNWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: LEUC_HALHL
Sequence: MTGKTLYDKLWDSHVVTEYDDGSALLYIDRQLLHEVTSPQAFEGLRLAGRQPWRVASNLAVTDHNVPTTDRSQPVEDPVSRVQIETLDRNCKDFQVIEFGIRDPRQGIVHVVGPEQGTTLPGMTLVCGDSHTSTHGALGALAFGVGTSEVEHVLATQTLVQKKARTMLIRIDGQLGRGVTAKDIILAIIGRIGTAGGTGYALEYGGEAIRSLSMEGRMTICNMSIEAGARTGMVAVDDTTIEYVRGRPNAPEGALWDQAVASWRHLVSDEDAAFDRVVELHADEIEPQVTWGTSPEMVASVNRRVPDPAEESDAVRARAMGRALEYMGLEPGTPLTDIPMDKIFIGSCTNARIEDLREAAAVVHGRRVAENIRQALVVPGSGVVKQQAEGEGLDRVFLDAGFEWREPGCSMCLGMNPDRLEPGERCASTSNRNFEGRQGQGGRTHLASPAMVAAAAIHGHFVDIRE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TM109_RABIT
Sequence: MAGSGSSAPWGKHLLHAVLMVLVALVLLHSALAQSHRDFAPPGQQRREAPVDLLTQIGRSVRETLDTWIGPETMHLISETLSQVMWAISSAISVAFFALSGIAAQLLTALGLDGDHLTQGLKLSPSQVQTFLLWGAGALVVYWLLSLLLGLVLAVLGRILGGLKLVIFLAGFVALVRSVPDPSTRALLLLALLTLYALLSRLTGSRASGAQLEAKVRGLERQVDELRWRQRRAAKGARSVEEE
What is the function of this protein?
May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (By similarity).  Can form voltage-gated calcium and potassium channels in vitro (PubMed:21381722).
What are the official names of this protein?
Transmembrane protein 109, Mitsugumin-23, Mg23.
What are the subcellular locations of this protein?
Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SP5G_BACC4
Sequence: MEVTDVRLRRVNTEGRMRAIASITLDHEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSGTRSKIQDAVLTEYHRLGELEEVEFEEAGAS
What is the function of this protein?
Essential for sporulation.  Interferes with or is a negative regulator of the pathway leading to asymmetric septation.
What are the official names of this protein?
Putative septation protein SpoVG, Stage V sporulation protein G.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: PURA_MYCSS
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELRGLEERGVDTERLLISADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVADVLDPAVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHRIADARLLLNQALERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTIDGKRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGRDQTIVRRDVLAPS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG027_MONPV
Sequence: MGIQHEFDIIINGDIALRNLQLHRGDNYGCKLKIISNDYKKLKLRFIIRPDWSEIDEVKGLTVFANNYAVKVNKVDYTFYYVIYEAVIHLYNKKTEILIYSDDENELFKHYYPYISLNMISKKYKVKEENYSSPYIEHPLIPYRDYESMD
What is the function of this protein?
Inhibits antiviral activity induced by type I interferons.  Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN.
What are the official names of this protein?
Interferon antagonist OPG027, Host range protein 2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG027 family.
Protein: MUTS_BAUCH
Sequence: MKELTDKSILNHTPMMQQYWQIKAQHSDVLLFYRMGDFYELFYEDAKLASQLIDISLTKRGFSAGEPIPMAGIPYHALDSYLAKLVALGKSVAICEQVGEPTINKGPVERRVVRIVTPGTLSDEVLLNERQDNLLAAMLQDKQGFGYATLDITSGRFIVSEPKDFEAMAAELQRTNPAELLYPDTQHNLALIEHRRGLRRRPIWEFELDTACQQLMIQFGTSSLKGFGIECAHLALRAAGCLLQYAKDTQRTAMPHISTITLERQEDYVVMDAATMRNLELTHNLSGGIEHTLVAVLDHTVTSMGSRMLKRWLQMPTKHLTTIENRQQSIYFLQGKFDILQPILRKIGDLERILARLALRSARPRDLARIRNALQQLPDIQSLLADNTSGMHLSQLLSNVGYFDNLCQLLERAIVISPSALLRDGGIIATGYNLELDELRALANNATDYLDILEMKERKHTGLETLKIGFNAVHGYFIQLSREQSHRAPKRYIRRQTLKHVERYIIPELKEYEDKVITSKSKALSLEKKLYDALLDMLLPYLTQLQLSATALAELDVLSNLAERADTLHYVCPMINNQPIINIIDGRHPVVEPLMSKPFIANTLSLSDQNHMIIITGPNMGGKSTYMRQNALIVLLAYIGSFVPASQAIIGPIDRIFTRIGAADDLVSGRSTFMVEMTETANILHNATCQSLVLMDEIGRGTSTYDGLSLAWACAESLASRIKAMTLFATHYFELTTLPNKIKGIVNAHFAAIEYNDTIAFMHSIQNGAANKSYGLSVASLAGIPRDVIKCASRKLHELENLSNNIALTTPLSSRSLPQFTQETSPVIQALQEIDPDSLSPRQALDLLYSLKQMI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CSP7_STRCL
Sequence: MATGTVKWFNAEKGFGFIAQDGGGPDVFVHYSAINATGFRSLEENQVVNFDVTHGEGPQAENVSPA
What are the official names of this protein?
Cold shock-like protein 7.0.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_PSEA8
Sequence: MNRPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALAE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CAPSD_BEYDV
Sequence: MSTVTWGKKRKRSGGDSKAKSRGSSSYIPRSVSSRRESLQVATFSWTSSGSGIKFSPGGAAYLVSNFPQGANDNCRHTNKTVLYKFMAKNTIYLDSSHYMKVFRAPFHFWLVYDKSPGANVPSTGDIFEGPSLFPHNPWTWTVSRAACHRFVVKKTWSCVVESNGIDPTKGQGATYYGPGPCNQVKSCNKFFKRLGVSTEWKNSATGDVGDIKEGALYIVGAPSQKSDVYVNGYFRVYFKSVGNQ
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: UCK1A_XENLA
Sequence: MASAGSLDVPERGHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDHRQRKVVILSQDRFYKVLTPEQKTRALKGQYNFDHPDAFDNELMHRTLTQILEGQIVDVPMYDFITHSRLPETTTVYPADVLLFEGILAFYNQEIRDMFQLKLFVDTDSDVRLSRRVLRDMKRGRDLEQILTQYTTFVKPAFEEFSLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWQRGVLNGRSQKRTFPGQGESGGLILPGKRTHLESSSRPH
What is the function of this protein?
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate.  Does not phosphorylate deoxyribonucleosides or purine ribonucleosides.  Can use ATP or GTP as a phosphate donor.
What are the official names of this protein?
Uridine-cytidine kinase 1-A, UCK 1-A, Cytidine monophosphokinase 1-A, Uridine monophosphokinase 1-A.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: ORF9B_BC279
Sequence: MDPKTSVVPPALHLVDPQIQLTIIRMEDAVVHGQSNAVPKVYPIILRLGSQLSLSMARRNLDSLEARAFQSTPIVVKMTKLATTEELPDEFVVVTAK
What are the official names of this protein?
Protein 9b, Accessory protein 9b, ORF-9b.
What are the subcellular locations of this protein?
Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host cytoplasm. Note=Binds non-covalently to intracellular lipid bilayers.
Protein: DTD_CUPMC
Sequence: MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEGRMNLPVQNMDGQGNAGGLLVVSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARAAHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.