PharMolix/UniProtQA huggingface dataset:
Protein: NID1_HUMAN
Sequence: MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALELSGALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVILGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERTRSFQLAVETFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQECVHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK
What is the function of this protein?
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin.  Also binds to collagen IV and perlecan.  It probably has a role in cell-extracellular matrix interactions.
What are the official names of this protein?
Nidogen-1, NID-1, Entactin.
Protein: LPXC_SHEB2
Sequence: MIFQRTVQKMVKTTGVGLHSGNKVTLSIMPAPVNSGIVLVRTDLSPAVAIPAKAEQVRETTMCTALVNDEGIRISTIEHLFAALAGLGIDNAVIEVDAPEIPIMDGSASPFVFLLQSAGIKEQAAPKKYLKIKRPVRVEDGDKWAELKPFKGFRVNFKIDFAHPEIARSQQHVVMDFSTSAFVKDISRARTFGFMRDIEYLRANNLALGGSMENAVVLDEYRVLNPDGLRYEDEFVKHKILDAFGDLYVAGHAILGEFTAYKTGHALNNQLVRALLAQQDAWELVSFEKEADVPVSFTVPGGAVFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: 3SOK3_NAJHA
Sequence: LECYQMSKVVTCKPEEKFCYSDVFMPFRNHVYTSGCSSYCRDGTGEKCCTTDRCNGARGG
What are the official names of this protein?
Weak toxin CM-3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYM_STAAM
Sequence: MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGHEVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRTSFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYYLMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHELDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQKDMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLTESIMVTGQPKPIFPRLDSEAEIAYIKESMQPPATEEEKEEIPSKPQIDIKDFDKVEIKAATIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLMGQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_ALIF1
Sequence: MANTLFDRTIAFAGICQAASLVQKMAKDGHCDQEAFDTAIQSILETNPSNTVAVYGKESNLRIGLECLVRDFDNTPSGSELTRYLISLMALERKLAGHRDGMSKLGERIGTIERQLEHFDIHDEQMLSNIASIYLDVISPMGPRIQVTGTPSVLQQPMTQHKVRALLLSGIRSAVLWRQVGGKRRHLIFGRKKMVEQAKIILAQI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL18_SHISS
Sequence: MDKKFARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: AROK_THEKO
Sequence: MRASASSAVTVVNAFATGVGSAIGIDLWTRAEVKLKGDGIEGEIRVRGEQVRDFRLVKAVADVFREKTGEEFGIKFRIESEIPIAMGLKSSSAAANALSKALADALGLDMSEMEVVKAGVEAAKRAGVTLTGAFDDACASYFGSLWVTDNLGMRVLHSSKVEPLPVVLLLPGKTLLTESLGGRDFSPIRPYVEEAVRLALEGEWRKAALINGLVYSTYLGHPIEPFRIALERGAVVGLSGKGPAVFAVTNEPEELAEEWEQFGKVLTTELR
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEM1_CANAL
Sequence: MSPDAIRVVVCGDDAVGKSSLITSLIKETIIEPQTNNVLPPITISRNDYIESSQEYLNDQDHHHHHQSSPSTMKNKRKHNNKRERERERESSINNVQPNEISEYIPNITTIIDTSSSDMTNLQKELKRADVIWLVYSDHYTYERISLHWMPLFRSMGVNLPIILCANKSDLFPKSKSNLKSTNSDEFVPLINEFKEIEAGVRCSAKNNYNVVEAFYLCQRAVTHPISPIFDAKEGNLKPGAIKPLKRIFWLSDTDQDGYLNFEELSELHKKCFGIEASKSDYEEIVNLIDQKILPSYNTTIETQTPPQQQHLATSAGTPNGTTTTTSKGISEDGFILLNKIYAESGRHETVWCILRAYHYTNSLSLSDKFLYPRLDVNPHSSVELSPTGYKFFVDLFIKFDKDNDGGLNEDELNTLFRSTPGIPKLWVESNFPSSIVCNEEGYVTLQGWLAQWNLTTFLSYKTTLEYLAYLGFDEGNSTKALKVTKPRKIRQKNGKTYRNAVNDRNVFNCFIVGAPKAGKSSLLESFLHGSYSDIYSPTIQPRLVVKDIELRGGKQCYLILEELGELEPAILENKSRLDQCDVICYAYDSSDPESFQYLVELREKHGHLLDEVPAVFVALKADLDKQQQRCDVQPENYTRDLFLNSPLHVSLAWNSSLHEMFIQLVDAAKTPSSATPGIELEVSVDQDDIKHIIMTGAAIAVVGLVSIWVLNSLRR
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
What are the official names of this protein?
Mitochondrial Rho GTPase 1, GTPase EF-hand protein of mitochondria 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: LPXC_SULDN
Sequence: MYQTTIKKSVELVGIGLHKGSAVKLRLEPLESNSGLIFYRSDVDVAIPLLPANVVDTKMATVIGKDGYVISTIEHMLSAIYAYGIDNLKIIVNADEVPVMDGSSASFCMLLDEAGVVQLDVPKKIMRIKKEIIVQEGEKYVKLSPSTDLKYGFTIKFPHPVIQQQEYVLNFTKQNYKDEIARARTFGFLHEVQYLRSKGLALGGSLENAIVLDDKKVLNPEGLRFDDEFVRHKILDAIGDMALIGMNFVGNYEALAGSHDLNHKLTLELLKDAENYEVIELVDEKTKELEKAYA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PSAC_NYMAL
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LIPA_ACTP7
Sequence: MTTATGTKPKKMEAFKMERGVKYRDAAKTSVIQVRNIDPDQELLPKPSWMKIKLPAASAKIDSIKHGMRRHGLHSVCEEASCPNLHECFNHGTATFMIMGAICTRRCPFCDVAHGKPLPLDPEEPRKVAETVQDMKLKYVVITSVDRDDLADRGAAHFAATVREIKALNPECKVEILVPDFRGRVEQAVEILKQNPPDVFNHNLENVPRLYREVRPGADYKWSLELLKIFKQEFPNIPTKSGLMVGLGETNEEILEVMQDLRDHGVTMLTIGQYLQPSRHHLKVERYVPPEEFDMFRSEAERMGFEHAACGPFVRSSYHADLQAKGELVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALE_NEIMB
Sequence: MKKILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRLKTITGQEIPFYQGDIRDREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFSIVFSSSATVYGDPGKVPYTEDMPPGDTTSPYGASKSMVERILTDIQKADPRWSMILLRYFNPIGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVFGDDYPTPDGTGMRDYIHVMDLAEGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAFEAASGLTIPYEVKPRRAGDLACFYADPSYTKAQIGWQTQRDLTQMMEDSWRWVSNNPNGYDD
What is the function of this protein?
Involved in the metabolism of galactose.  Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis.  Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: RPAC1_SCHPO
Sequence: MAAVDRSRTEISVLSDRVTDVGSVDFPGYYFDEDNIWDLDKFKKNLKVSITSLDQETMVFEISGIDASIANAFRRILIAEIPTLAFEFVYIINNTSIIQDEVLSHRIGLVPISADPDMFKWFQHPLPGQEATHTDYDTVVFSLNKKCEFNKNAATDEKDPKRLYVNSEVYSGDLIWKPQGRQEERFADNPIRVVNPDIVVAKLRPGQEIDLEAHAILGIGQDHAKFSPVATASYRLLPTIHILSPIEGEDAVKFQKCFPKGVIELEEGPDGKKQARVADVRKDTVSRECLRHPEFADKVQLGRVRDHYLFSVESTGIMKPDVLFIKSIAVLKSKCLAVKSSLQNISSD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.  RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I and III subunit RPAC1, RNA polymerases I and III subunit AC1, DNA-directed RNA polymerases I and III 40 kDa polypeptide, AC40, RPC39.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OPAC_ASPUT
Sequence: MTVPQYIGPNRTGITVIIIGLGIGGLTAAISCHLQGHHVIGFDKLENLEPYGDGLILTPNGSQVLRDLDDTGAIAAWINTWAYNCRDCKIYNTDGVHVGQHPIPDTDKGLSLLPRGGLVQILYQTAKRLGLDLRLGVKINEFVEDVDQARVIIDGVHVQGDCIIFADGANSRGREAVSSCNVKPYYSGFSVYRGRADGAALIKDPQCHWLLSKEGAIDQATGFAGPEMYVQLATCGGGQASFCIGITQRFALQHTQSAENFWTTPIDKNEMLDKISYWKCINQIRPVIDKMAKDQFILCPLLRAGVLDSWVSPIGRIAVIGDAAHPFFPTSAQGAAQAIEDAATLAITLALAGKNNIRLGLKAMEAMRKHRATYIQRNAWRVNDAWFGSPVEERIGEKAAPAIGVIDWITEHCCRTYASNEFDRVQDSIATGQPYVPTNIPSQQFKEAAEWIANRNDEKEKN
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of oxepinamides, derivatives of anthranilyl-containing tripeptides that share an oxepin ring and a fused pyrimidinone moiety (PubMed:33004788).  The nonribosomal peptide synthetase (NRPS) opaA assembles the quinazolinone core with D-Phe incorporation (PubMed:33004788).  The first adenylation domain (A1) of opaA loads and activates anthranilic acid whereas the second A domain (A2) is for activating of L-Phe, which is then converted to D-form by the E domain (PubMed:33004788).  The third A domain (A3) is responsible for L-Ile activation and the terminal condensation domain C3 for cyclization and releasing the NRPS product protuboxepin K (PubMed:33004788).  The cytochrome P450 monooxygenase opaB then catalyzes alone the oxepin ring formation to convert protuboxepin K into protuboxepin A (PubMed:33004788).  The flavoenzyme opaC installs subsequently one hydroxyl group at the oxepin ring, accompanied by double bond migration, to form 15-epi-oxepinamide E (PubMed:33004788).  The epimerase opaE changes the D-Phe residue back to L-form, leading to oxepinamide E, which is further methylated at the hydroxyl group at C-12 by the O-methyltransferase OpaF to yield oxepinamide F (PubMed:33004788).
What are the official names of this protein?
FAD-dependent monooxygenase opaC, Oxepinamide F biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL9_WOLPP
Sequence: MLIILKENITTLGKLGEVVKVKPGYARNFLFPQKKAMKATKENLIKLEEQRLLLEEENTKKLNAAKVLASSLHDKFIILIKQASEDGKIFGSVTTREIAKTLLQEGYDISHHSLSLGGISIKNLGEYQVNIELHSKVIVPITIYVVRSEKDAHELRQAKLQNQKSEQQEAEQDASKEAADADDS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TYSY_SHEB2
Sequence: MKQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVSTKKCHMRSIIHELLWFLKGETNVAYLRENKVSIWDEWADDNGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKSQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTALQLSREPMPLPTMTILRKPESIFDYQFDDFELTNYAPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F10A1_PONAB
Sequence: MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPKAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNLPGGMPGMGGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISKLSAKFGGQA
What is the function of this protein?
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40.  Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein.  Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).
What are the official names of this protein?
Hsc70-interacting protein, Hip, Protein FAM10A1, Protein ST13 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAM10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y286_MYCGE
Sequence: MIFSISKRKLICGFLLVILTIGGVLGGVYLVTKNNKDNYQNESNFNNQEQISKIPNFKAIGPETQRILRERNYPLDDSGYYVYKYGEINRYLRNESELDELINYRVMVPSLKLHHKRVNFDKAFLESKLRKWIIKAIKQHNYFQHFENEPNLRVQYNMNIPAQKIDVNAVWSYKKDNDAATGKPIRYWDQFELKLK
What are the official names of this protein?
Uncharacterized protein MG286.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RBFA_CLOD6
Sequence: MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTNDLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGMYMDSLIKRVNEKNAQQNEDENYDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_TRIEI
Sequence: MLNKNIGYISPDYLYKYNSPINTEAILKIRQERQAKLFKFSHEKYYKAVQTIADIQSNFFDCSSAVIKVGHPEEISPGQKQRLYHCLQTFCPWKKGPFELFGVNIDAEWRSDWKWDRILPHISSIKNRKVADIGCHNGYFMFRMVDQQPELVIGFEPYSKHFWNFQLIQNIVKQKMLAFELLGVEHIHYYPQFFDTIFCLGILYHHTDPIGLLRKMRQALGPKGEVIIDCQGIPGDLPVALTPQKRYAQARGIWFLPTQSCLENWIGRAGFSDINCFFAAPLSVEEQRRTIWANIDSLPEFLDPHNPSLTVEGYPAPWRYYAIARK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SPEH_ACIF2
Sequence: MRSLGHQIVADFYHCDGSTLSDVDFVTDAMLEAARRANCTIVTQTFHHFSPYGVSGAVIVAESHLAIHTWPEYGYAAVDVFTCGDIIQPEDALNYLKEAFGAGQVSTMEMKRGQVDMMGVPAHELRVKPALCA
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: HHP1_ARATH
Sequence: MDQNGHNDEAETVSCGNGNCKSKIVPGDDHGGDESSGTKRRKKRKTQQKTMKRRELMSYCELPEYMKDNEYILNYYRADWSIRDAFFSVFSFHNESLNVWTHLIGFIFFVALTVANIIHHDGFFPVDAKSPGNVTRWPFFVFLGGSMFCLLASSICHLFCCHSKELNVFLLRIDYAGITAMIITSFFPPIFYIFQCTPRWYFIYLAGITSMGIFTIITLFTPSLSAPKYRAFRALLFASMGLFGIVPAAHALVVNWGNPQRNVTLVYELLMAVFYLVGTGFYVGRVPERLKPGWFDRVGHSHQIFHVFVLLGALSHYAAALLFLDWRDHVGC
What is the function of this protein?
May act as a negative regulator of abscisic acid (ABA)-mediated osmotic stress signaling and function in cross-talk between cold and osmotic signaling.
What are the official names of this protein?
Heptahelical transmembrane protein 1, PAQR family protein HHP1.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 5057R_ASFM2
Sequence: MFSLQDLCRKNTFFLPNGFNKHTLQLLGLYWKEHGSVHRVEKDNIMIQNELVLSINDALLLAGEEGDTDVVQLLLLWEGNLHYAIIGALKTEKYNLICEYHSQIEDWHILLPMIQDPETFEKCHDLSLQCDFICLLQHAIKYNKLSILVKYKEDLLNIRIRHRVQSLFVLACENRRTEIIEWIGQNLSIPEPDAIFSIAIATKDLELFSLGYKIIFDYMQRQGILQLSNGLRMVVLNRHISMAIDNGLLPFVLETLKHGGNIHRALSYAVSHNRRKILDYLIRQKNIPPNTIERLLYLAVKNQSSRKTLNLLLSYINYKVKNVKKLVEHVVDHNSTLVVTILLEKKINLIDAVLTRLVKHSTYFRVREFIQEFSISPEKFIKIAVREKRNVIIKGISEDIWENPAERITYLKQIVHTIKYESGREFLINIIHTIYQSYSLKPEEILKLARFYVKHNATTHFKDLCKYLWLNRGTESKKLFLECLEIADKKDFPAIKNIVSEYINYLFTAGAITKEEIMQVYTLEYAMY
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  Interferes with host NF-kappa-B promoter activity mediated by TLR8.  Mechanistically, inhibits the phosphorylation and subsequent nuclear translocation of host NF-kappa-B RELA subunit downstream of TLR8.  Promotes the expression of the autophagy-related protein host ULK1 to degrade host STING and inhibit the interferon response.  Inhibits also JAK1- and JAK2-mediated signaling and thus negatively regulates the IFN-gamma signaling.
What are the official names of this protein?
Protein MGF 505-7R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: TYSY_LISMC
Sequence: MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIWNEWAFERFVKSDDYKGEDMTDFGLRAERDSAFKEVYQAEMEKFKARILEDEAFANKYGELGNIYGKQWREWKTSQGETIDQLADLIEMIKTNPNSRRLIVSAWNPKDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLEVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIKAPISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1987_PECAS
Sequence: MNEPLKPRVTFDDVSPQEPQPQLRAGLAFDEQSSTPFSPISREEEVPEEGAAEEAISAALRPKRSLWRRMVMAGVALFGISALAQGVQSLHNAWVQQDWIALGGITAGSLIVAAGVGSLAVEWRRLYRLRERAEERDMARDLLHSHGVERGREFCEKLARQAGLDSGHPAIQRWQASLHETHNDREVLELYARLVQPVLDTQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIAALYGIELGYFSRIRLFRLVLINIAFAGASELVREIGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWLDDKPRLGDFRRELIGQVKETLQKGR
What are the official names of this protein?
UPF0283 membrane protein ECA1987.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5534_VIBVU
Sequence: MNLSAKTVVVIAIGAALYGIGGLPMFGIPVFANTTLKPAMAVLALFSVLFGPLVGFLVGFIGHWVTDLFAGWGVWLTWVLGSGIVGLIIGLFPSLTRNRLEKGEFNLKDFSLFVVLALLGNVFGYGCSAFLDTILYAEPFTKVFTQLTIIASGNTVLIAIVGYFILKSVAKRNKQSRNLTEA
What are the official names of this protein?
UPF0397 protein VV2_1534.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADM_PYRAB
Sequence: MIRGLFVGRFQPVHKGHIKALEFVFSQVDEVIIGIGSAQASHTLKNPFTTGERMEMLIRAIEEAGFKKRYYLVPLPDINFNAIWVPYVESMVPKFHVVFTGNSLVAQLFRERGYKVVVQPMFRKDILSATEIRRRMIAGEPWEDLVPKSVVEYIKEIKGVERLRNLATNLESSEKELQAPIRIPEF
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_BORPE
Sequence: MPIVRLKENEPFEAALRRFKRTIEKTGLLTELRSREFYEKPTAERKRKHAAAVKRHYKRIRSQQLPPRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.