PharMolix/UniProtQA huggingface dataset:
Protein: NADE_LEVBA
Sequence: MRAKQREIIDALKVKPTIDPATEIRRSVDFLKAYLQRYDFMKTLVLGISGGQDSTLTGLLCEQAVTELRQETGDNDYRFIAVRLPYGEQADEDDAMMAIDFMDADEVQRVNIKPATDAMIQAVETSGKPISDFNKGNVKARQRMIAQYAIAGARSGAVVGTDHAAEAVTGFYTKYGDGATDICPIWRLDKRQGAAMLAQLGAPEHLYKKVPTADLEDDRPALPDEAALGVRYEDIDDYLEGRSVSEAAASRIEDWYAKTAHKRHLPVNVYDTFWQE
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PYRD_POLNS
Sequence: MIDRYSLLRPWLFCIDPEKAHNLTLSNLDRAQRWGFLERLITKPINDPQVLCGIEFSNPVGLAAGLDKDGKYIDALAALGFGFLEIGTVTPRPQPGNPKPRMFRLPEAQAIINRMGFNNDGVEACVARVRCSKFWQNGGVLGMNIGKNASTPIEEASRDYILAMEAVYEIATYITINISSPNTQNLRALQGEEMLRELLGSLGEARKHLCDRHGVRKPLFLKIAPNLDQGDINLIADLLLEFGIDAVIATNTTISRDAVKGMEFGEEAGGLSGAPVRNASNIVIKALKARLGNQLPIIGVGGIMSGVDAREKIMAGASLVQLYSGLIYRGPDLVYKCATVLRQP
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAR_NEUCR
Sequence: MSQQQNPPYGRRLILDIIKERALNEPNREWVSVPRSSDPKDGWKILTYLDAYNGINRVAHKLTQVCGAAAPGSFPTVAYIGPNDVRYLVFALGAVKAGYKALFISTRNSAEAQVNLFELTNCNVLVFDQSYKATVQPWLHEREMTAILALPADEWFPADQEDFPYNKTFEEAEWDPLMVLHTSGSTGFPKPIVARQGMLAVADQFHNLPPREDGKLMWIVEMSKRAKRLMHPMPLFHAAGMYISMLMIHYWDTPGALGIGERPLSSDLVLDYIEYADVEGMILPPAILEELSRDEKAIQSLQKLNFVSFGGGNLAPEAGDRLVENNVTLCNLISATEFTPFPFYWQYDQKLWRYFNFDTDLFGIDWRLHDGESTYEQVIVRKDKHPGLQGFFYTFPDSSEYSTKDLYKRHPTHEDFWIYQGRADNIIVFSNGEKLNPITIEETLQGHPKVMGAVVVGTNRFQPALIIEPVEHPETEEGRKALLDEIWPTVVRVNKETVAHGQIGRQYMALSTPGKPFLRAGKGTVLRPGTINMYKAEIDKIYEDAEKGVATDEVPKLDLSSSDALIVSIEKLFETSLNAPKLEADTDFFTAGVDSMQVITASRLIRAGLAAAGVNIEASALATRVIYGNPTPKRLADYLLSIVNKDSNQGTLDNEHHVMEALVEKYTRDLPTPKQNKPAPADEGQVVVITGTTGGIGSYLIDICSSSSRVSKIICLNRSEDGKARQTASSSGRGLSTDFSKCEFYHADMSRADLGLGPEVYSRLLSEVDRVIHNQWPVNFNIAVESFEPHIRGCRNLVDFSYKADKNVPIVFVSSIGTVDRWHDEDRIVPEASLDDLSLAAGGYGQSKLVSSLIFDKAAEVSGVPTEVVRVGQVAGPSSEKGYWNKQEWLPSIVASSAYLGVLPDSLGQMTTIDWTPIEAIAKLLLEVSGVIDNVPLDKINGYFHGVNPERTSWSALAPAVQEYYGDRIQKIVPLDEWLEALEKSQEKAEDVTRNPGIKLIDTYRTWSEGYKKGTKFVPLDMTRTKEYSKTMREMHAVTPELMKNWCRQWNF
What is the function of this protein?
Carboxylic acid reductase that shows a broad range of substrate specificity towards aromatic acids, especially to phenyl carboxylic and phenyl acrylic acids, to convert them into their respective aldehydes (PubMed:4389863, PubMed:11946054, PubMed:27917101, PubMed:29515539).  Also able to use aliphatic acids as substrates (PubMed:29515539).
What are the official names of this protein?
Carboxylic acid reductase, CAR, Aryl aldehyde:NADP oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the adenylate-forming reductase family.
Protein: TM199_PONAB
Sequence: MASSLLAGERLVRALGPGGELEPELLPRKLRAELEAALGKKHTGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVITIFNFIVTVVAAFVCTYLGSQYIFTEMASRVLAALIVASVVGLAELYVMVRAMEGELGEL
What is the function of this protein?
In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.  Necessary for endolysosomal acidification and lysosomal degradation (By similarity).  May be involved in Golgi homeostasis (By similarity).
What are the official names of this protein?
Transmembrane protein 199.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Partial colocalization with GOLGB1.
Protein: ECPA_KLEP3
Sequence: MKKKVLAIALVTAFTGMGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDATATAFKLTSRLITNTLTQLDTSGSTLSVGVDYNGAAVEKTADTVMIDTANGVLGGNLSALANGYNASGRTTAQDGFTFSIISGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP plays a dual role in early-stage biofilm development and host cell recognition.  Major subunit of the fimbria (By similarity).
What are the official names of this protein?
Common pilus major fimbrillin subunit EcpA, MatB fimbrillin.
What is the protein family that this protein belongs to?
Belongs to the EcpA/MatB fimbrillin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: PROA_SHEPA
Sequence: MNNDEYLTALGQNAKQASYALATLSGQQKSALLRCIANKLTAAKDDIVAANQQDVADAKANGLSDAMIDRLLLDETRLMGVISDIDNVIGLTDPVGCEIDSRLLDNGLRLSRRRVPLGVIGVIYEARPNVTVDIAVLALKTGNAVILRGGKETLSSNKALCKVIRSAMVEQGLSEDCVQLIDNPDRALVSGLLKLDKYVDMIVPRGGQNLQRLCAEQATIPVILGGIGICHIYVDAAANLEKAVAVIENAKVQRPTVCNALDTVLVHASHAKAFIPVLAKHLSGLGVKFYGCEQTQAILGAEKIEVSAADDESYSTEWLSLTLGLKVVADLESAVEHIRTFSSGHSESILTDNIHTASEFMNAVDSAAVYVNASTRFTDGGEFGLGAEVAVSTQKLHARGPMGLEALTTYKWLAWGDYTVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCH_ARATH
Sequence: MAQTVVLKVGMSCQGCVGAVNRVLGKMEGVESFDIDIKEQKVTVKGNVEPEAVFQTVSKTGKKTSYWPVEAEAEPKAEADPKVETVTETKTEAETKTEAKVDAKADVEPKAAEAETKPSQV
What is the function of this protein?
Involved in copper homeostasis.  Can complement the yeast mutants atx1 and sod1.
What are the official names of this protein?
Copper transport protein CCH, Copper chaperone CCH.
What is the protein family that this protein belongs to?
Belongs to the ATX1 family.
Protein: MSBA_PARXL
Sequence: MSAKPTLSKPIGSGEASSPAVVFRRLWPYIKPLIWVLIGAIVAMAVSAATDAAIPALLKPLLDKGFGAHANDRAKWFVPAAVIGLALIRSLSQYASGYLLAYVTNKILLDLRLKMFDRMIHTSVAFFQRETASTVINAIVFEVNQILNVLLSVLVTLVRDSLTVVFLLGYLFYLNWRLTLIVAVLLPAIGWLVGKINRRLRRLNREHQLLTNELSYIVEESVGGYKVVKVHNGEQYEMDRFESMSKRLRGYAMRMTVSGGLAQPLTQFLASIALAVVITIAVVQSSSDQTTVGGFVAFVTSMLLIISPLKHLMDVNQPLQRGMTACEMIFGLIDEPSEPEGGGKPLERAHGAVEFRDVSFVYSGNATHNRHTLDQISFRVAPGEMIALAGPSGSGKTTLVNLLPRFFDPTGGQILVDGVAIPEYDLHALRSQIAMVSQDVVLFNDTVANNVAYGQTADAGKVKAALRAANLWDTVEAMPKGIETLVGDNGMMLSGGQRQRLAIARAIYKDAPILILDEATSALDSESERHVQAALETLMKGRTTLVIAHRLSTIERADRILVMEAGRIVESGSHRELLAQDGLYAHLHRIQFQQSAA
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYDP_SHEB9
Sequence: MSCLPALDKFLQNYHQAYLTSLGELPRYYPQGEPSVCIQGEFHADLDQAVSWQPVKREVEGSFANVEHALELTLWPEINHFYGQYFSAPLLFDSKWGTGELLQVWNEDDFTCLQQNLIGHLMMKKKLKQPPTWFIGLLDEGDKMLTINNSDGSVWIELPGEIPTQQLSPSLAEFIGALSPRIAPPVKHEELPMPALEHPGIFASFKRMWQNLFGKR
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: NIPA5_ARATH
Sequence: MVYSSGSWRDAYKGMSSDNVKGLVLALSSSIFIGASFIVKKKGLKKAGASGLRAGSGGYSYLLEPLWWIGMITMIVGEIANFAAYAFAPAILVTPLGALSIIISASLAHIILQEKLHTFGILGCALCIVGSVTIVLHAPQEQDIVSVLEVWNLATEPAFLFYAAAVVGAAIVLIVQFIPLYGQSHVMVYIGVCSLIGSLSVMSVKALGIALKLTFSGTNQLGYPQTWVFTVIVLFCVITQMNYLNKALDTFNTAVVSPIYYVMFTSLTILASVIMFKDWDRQSGTQIMTELCGFVTILSGTFLLHTTTDMVDGESKGNLSSEEDSHLLLRIPKHSEDSNGFVQDGIILSLRRQESAKSPRPARQNKQLEDDLEAVPLRRQESSLRS
What is the function of this protein?
Acts as a Mg(2+) transporter.  Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
What are the official names of this protein?
Probable magnesium transporter NIPA5.
What is the protein family that this protein belongs to?
Belongs to the NIPA (TC 2.A.7) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Recruited to the cell membrane in response to low extracellular magnesium.
Protein: MAP2_BOTFB
Sequence: MAAQVTDALKNLKVKDPNAVVESAAEAKANGNAQPEAEAEDSDDDDEEPVNGEGAGEGGAKKKRKRKKKPKKKAGANPKVQSSPPRVLLSNLFPSGEYPVGEEVEYRDENNYRTTSEEKRYLDRMNNDFLQEYRQGAEIHRQVRQYAKANIKPGQTLTEIAEGIEDSVRALTGHPGLEEGDNIKGGVAFPTGVNLDHIAAHYSPNAGNKTVLAYENVMKVDFGVHINGRIVDSAFTIAFDPMYDNLLEAVKQATNTGIKEAGIDARLGEIGEHIQETMESYEVEIKGQTYQVKPIRNLNGHDILQWKIHGGKSVPIVKSNDQTKMEEGEVFAIETFGSTGNGYVRDDLECSHYAKVADAPNVPLRIASAGKLLNVINKNFGTLPFCRRYLDRLGQDKYLLGLNALVSHGIVQDYPPLVDKKGSYTAQFEHTIVLRPNCKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3334_RHOPS
Sequence: MLVCIPEILSKHEVTEFRRLMDQADWEDGRSTAGAQSAMVKRNEQLPPDSELARMLGRRIVSALTANPKFVSAAVPLQIFPPLFNRYAASGNHHFGIHVDNAVRGDPLTGLRIRTDLSVTLFLAEPDEYDGGELVVEDTYGSHEVKLPAGDCVLYPSSSLHMVTPVTRGARVASFFWLQSMIRDAHARSMIYDLDGAIQALVERLGRDDPETVKLTGIYHNLIRYWADV
What are the official names of this protein?
PKHD-type hydroxylase RPD_3334.
Protein: 5059R_ASFK5
Sequence: MFSLQDLCRKNLFTPLEPLGKHVVQRLGLYWEGHGSLKRMGHCFVCVDQIHILSINLAIKIAAAEGNEEIVKLLLLWGGNLHYAIIGALESRQYELILIYENQIGDWHDILSLIRDPVIYERCHELNVTCTFQCLFQHAIRHNMVSILQKYREDLANNRRMIQLLYEMACRLQNYDIITWIARNWHVFNIEAIFSIAFIRKDLTLYSLGYMFLLDRMSIEDRNFKSIITRHLEYAAKKGLFDFVLESLKYGGQVDTVLFQAVKYNHRKILAYFIHETPRKTVEKLLLHAVESRASKKTMNLLLSSLNYSIHSIIKKLLYAVVKHKYMLVIKLLLERPKKKINLVDAVLYRLVKHSTNAEIVKFMNEFSVSPERVIKVAARLMRVDLIKNISKDVWENKLERIKHLKQIVYTMKHRNGKNLLMYNIYNITGYTYMNIKEAFNLTKFYAVHNATCLFKEMCKNCFVHDLIQLRELLEDCLHIANKHAYIQIAEAANEYIKYIDDIYISLK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-9R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: CALM3_ORYSI
Sequence: MADQLTDDQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYDEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-3, CaM-3.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: K1A_STIHL
Sequence: RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
What is the function of this protein?
Peptide with both antimicrobial and neurotoxin activities.  Inhibits voltage-dependent potassium channels.  Potently blocks Kv1. 1/KCNA1 (IC(50)=6. 7-87 pM) and Kv1. 3/KCNA3 (IC(50)=10-250 pM) (PubMed:8567178, PubMed:15665253, PubMed:9830012, PubMed:10545177, PubMed:23919482, PubMed:26288216, PubMed:28194851).  Less potently blocks Kv1. 4/KCNA4 (IC(50)=0. 31 nM), and Kv1. 6/KCNA6 (IC(50)=0. 16 nM) (PubMed:9830012).  Shows moderate activity on Kv1. 2/KCNA2 (IC(50)=9 nM), Kv1. 7/KCNA7 (IC(50)=11. 5 nM), and KCa3. 1/KCNN4 (Kd=0. 03-30 nM) (PubMed:10419508, PubMed:9830012).  Blocks Kv channels by binding to a shallow vestibule at the outer entrance to the ion conduction pathway and occluding the entrance to the pore (PubMed:10419508, PubMed:9830012).  Shows antibacterial activity against all tested bacteria (the Gram-positive bacteria B. subtilis and S. aureus, and the Gram-negative bacteria S. typhimurium and P. aeruginosa) (PubMed:28796463).
What are the official names of this protein?
Kappa-stichotoxin-She3a, Kappa-SHTX-She3a, Potassium channel toxin ShK.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1a subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CCME_HAES1
Sequence: MNPRRKSRLSVVLFIFLGISVASALVLYALRQNIDLFYTPTEVVNGKNNESHTKPSIGQRIRIGGMVVEGTVERDPKSLKVRFDLNDIGPSVTVIYEGILPDLFREGQGIVAQGVLIEPTVLNATEVLAKHDENYVPPELEAQMQKIHKPMGISDLKNESDRDRQEKQFKEGNQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL17_COXBN
Sequence: MHHRKSGRHLNRTSAHRKAMLRNMAVSLFQHELIKTTLPKAKELRRVVEPLITLAKEDTVANRRLAFNRLRDDAIVAKLFKEIAPRHKERPGGYCRVLKYGFRNGDSAPMAIVELVDREESESSED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: EFG_DEHMC
Sequence: MSDRKYPLERVRNIGIIAHIDAGKTTTTERILYLTKRTHKIGNIDEGTTVMDWMEQEKARGITITSAATSAYWNGHHLNIIDTPGHVDFTAEVERSLRVLDGGVVVFDGVAGVEAQSETVWRQASRYGVPRICFINKMDRTGANYERTLGMIAERLKAKYLPLQIPIGCAETFRGNCDLLDFKCYGMDNSPEEPVETFDLPAAEKERAVKFRNMMIERLAEEDDEVMEAYLAGEELPIEKLKAAIRRVCLANKAIPIFCGTSLRNKGVKRLLDAVCDYLPSPLDIPAMKGTDPKTGESIERHTSDTEPFSALAFKIVSDPFVGRLVYFRIYSGSISAGSGAYNSTRGERERIGRLIRMHANDREEIEYADAGEIVASLGLRNTFTGDTLCDQNAPILLENIKFPEPVINLAIEPKTRSDQDKMTEGLQKLAEEDPTFKVKFDDETGQTVIYGMGELHLDVLVSRLLSEFKVNAGVGKPRVAYREAITAHAKAQGKFVRQSGGRGQYGDVTIEIEPRERGAGYEFVDNVKGGAIPRNFLMAAESGIRDTLETGVYAGYPMVDVKVIATDGSYHDVDSNENAFKMAGSMAIKAAVAKAKPILLEPIMKLEAVTPEEYMGDVIGDLNSRRGQIISVEPSPETTVITGTVPLAESFGYTTDLRSVTKGRATFSMEFESYREMPGELATQVVEAAGKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP2_CUPLA
Sequence: MASAAPASSICIKSASCSALAPGRISSLRSVSLPVSRKSFFSRRGSFSLRVNCQAKPETVTKVCNIVKKQLALPDDSDVSGVSKFSALGADSLDTVEIVMGLEEEFGISVEEESAQSIQTVQDAADLIEKLMEKKGH
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 2, chloroplastic, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBFA_HYPNA
Sequence: MARRQTPPGLPSQRQLRAGEIVRHALAEIISREDFRDPDLSNVIVTVGEVRCSPDLKHANIFVTPLGDDSEEGRKRLADALTRAKGFLRTRLGREIELKFTPELHFIADSSYDEATAIDRLLNDPRVRRDVESEG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFC_LACLA
Sequence: MDKKKGILLVALGTPRSCEADDVRDYLKEFLGDPLVIQKPRWLWLPILNGIILKVRPQKSAEMYKKIWTDEGSPLMIYTVAQAKQLQDMREDFDVRFAMTYGEPRIDKVIAEMKESGVEEITVLPLYPQYSLTTVEPVIQQVKKIDDKIKVIRDFHKVESYSDLLAESIREKWQANDYDKLVLSYHGIPLSYVTKKKDAYEEQCKETTRLVVSKLGLREEEYEHTYQSKFGPEKWLEPATIDRVAELPKENAKKVLICSPAFVADCLETLFELEIENKEVFVENGGETFDFVHPFNDSLDFTRVLSEVVDQNRL
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEST1_MOUSE
Sequence: MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSFVEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKEDLELWSKEEADTDKKESGYSSTIGCFLGLQPKNYHLPLKDLKTKLLCSKNPLLEGQCKDANQKNQKDVWKFKGLDFLKCVPRFKRRGSHCGPQAPSSHPTEQSAPSSSDTGDGPSTDYQEICHMKKKTVEFNLNIPESPTEHLQQRRLDQMSTNIQALMKEHAESYPYRDEAGTKPVLYE
What is the function of this protein?
Forms calcium-sensitive chloride channels.  Permeable to bicarbonate (By similarity).
What are the official names of this protein?
Bestrophin-1, Vitelliform macular dystrophy protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.
Protein: DNAA_LEIXX
Sequence: MADGEESISVAWQSVLDKLETDDRITPQLHGFLSLVEPKGIMAGTFYLEVPNEFTRGMIEQRSRVPLLNAIGTLDNTLAVTTFAIVVNPEIQQESLSTVGEPEPTPAPYLDVATFTVAPPAEITAPPRNGDTRLNSKYSFDNFVIGQSNRFAHAAAVAVAEAPAKAYNPLFIYGDSGLGKTHLLHAIGHYAMSLYPGIRVRYVSSEEFTNDFINSIANNRGSSFQARYRNIDILLIDDIQFLQRAVETQEAFFHTFNTLHDHNKQVVITSDLPPKHLTGFEDRMRSRFEWGLITDVQVPDLETRIAILRKKAQSEKIQVPDDILEFMASKISSNIRELEGTLIRVTAFASLNRTPVDMPLVQTVLKDLITLDDDNVIAPTDIITNTAEYFKLTVDDLYGSSRSQAVATARQIAMYLCRELTNLSLPKIGQLFGGRDHTTVMYANKKISELMKERRSIYNQVTELTSRIKQNHR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_BUCAI
Sequence: MKFIINNNILIKNLQKISRLLVKNTSLPILDNVLINIKNGMLSLTGTNLEIELVAMIQLSTEHISGTATISGRKLLDICRNSLNSSNIEMQLNNNKMHIISGNSRYILTTLPYDSFPVHHDFHHISEFFIPSDILKKMIEKIQFSMAKQDVRYYLNGILLEKTDRSLYAVATDGYRLGISKFFLKENIIPFSIVIPRKGVIELYRLLNIPKQPIKVLVGKNNIRVHIEDLIFTTQLIEGQYPDYKSVLLENKNNFITLNSKLLKQSLLRAAILSHEKFCGVEIHIRNGQFKVLSDNQEEEIAEDRFNINYTGNTVKISINVYYIIEILNSITSENIFLFLNNANNSIQIEAENDASILYVVMLLKR
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BACAA
Sequence: MNLETIIGLEVHVELKTNSKIFSASPTEFGAEPNTQTSVIDLGYPGVLPTLNKEAVNFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGKKKRIGITRLHLEEDAGKSTHTADGSLVDYNRQGMPLIEIVSEPDMRTPEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEKFGTKAELKNLNSFTYVQKGLEHEQVRQEKELLSGGIIQQETRRYDEATKKTILMRVKEGSDDYRYFPEPDLVELYIDDAWKEEVRASIPELPDARKARYVAEIGLPAYDAHVLTLTKEMSDFFEAAIADGADAKLTSNWLMGEVLAYLNKQQKELKDVALTPAGLSKMVQLIEKGTISSKIAKKVFNELIEKGGDPEEIVKAKGLVQISDEGTLRKVVTEILDNNEQSIEDFKNGKDRAIGFLVGQIMKATKGQANPPLVNKILLEEINKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: VATA_CHLCV
Sequence: MVATSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVNVNDTWLKAEVIEVVGQEVKIQVFEDTQDVCRGALVTFSGHLLEAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALCKNTLWEYTPKAVVGDVLVRGDALGFVKEGYFNHKIMVPFSCFKEVTITWVISEGSYSVDTVVAKARDAEGKEYSFTMVQKWPIKQAFIQGDKVPCHEIMDVGIRILDTQIPVLKGGTFCTPGPFGAGKTVLQHHLSKYAAVDIVILCACGERAGEVVEVLQEFPHLTDPHTGESLMHRTCIICNTSSMPVAARESSIYLGITVAEYYRQMGLHVLLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSPAGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDQVGDILENKIQGWGKAVKKANYFLREGSEIGKRMEVVGEEGIPMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMSRIFDAKFSFDCPDNARSFFLELQSKIKTLNGQKFLSEEYKEGMEVVLRLLETKMVQTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.