PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_METCA
Sequence: MTKYIFITGGVVSSLGKGIAASSLAAILEARGLKVTLTKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFVRTTMGRANSFTTGQIYENVIRKERRGEYLGATVQVIPHITDEIKRGIRLSAEGYDVALIEIGGTVGDIESLPFLEAIRQMRVDLGEERSLFIHLTLVPYISSAGELKTKPTQHSVKELRTIGIQPDILICRSDRPIPKSECRKIALFTNVQEDAVIASVDADTIYRIPALLHEQQLDEIVVRKLRLDAGPADLSEWHRVVDALQNPERSVTVAMVGKYVNHSDAYKSLSEALVHAGIHTRTRVDIRFIESEEIEDHGTGALEGVDAILVPGGFGERGIEGKIAAVKYAREHRVPYLGICLGMQVAVIEFARNVAGLEGAHSTEFLPSSPHPVIALITEWKTEAGGIEYRSGDSDLGGTMRLGGQKCRLVPNTLAHATYGKDVITERHRHRYEFNNHYLKTLEAAGLRVSGKSLDGRLVEMVEIPEHPWFLACQFHPEFTSTPRGGHPLFSGFVRAARARSEGTSPPESGGAQP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RPP30_DICDI
Sequence: MVYYDLNIDSSLPEPKIKSMLSLHTKYGYDSVAITHTVEGKIGYKDVCKIKKIQIEDDSEKSTSSGWMKMGDSNKTIKQYTRLQVICKTMAEFQMITANNPVVQSYDIISVVPYDVSVFNAACNSNEIDIITIDTFSKFIIKPERVRQCIAKGIFIEILYGNLFGIDADRIAFFQIASSLVRSSFGKNIILSSSGKSSTTLRSPYDLSNLGHLFGLTFDQAKAAVSKHPHTAVLHAITRRTKGIATVTDPNLLKDLELWKLERKEDTQPTNNNIPHEKHINKESTGKETIPKPTTTTTTTTTTTTTAKTKTPTPTPTTEKTPSIPTQPPQKPTAKSNKKTTTNTTSTAQKQGKMDIDIDNNKRKRE
What is the function of this protein?
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit drpp30, RNaseP protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIN56_CAEEL
Sequence: MDHHAMYRTAEFNKTTVRLLAEFIEKTGQNATIVNMDSFLEFFAYLNPTAPIPTVPEIEKQLLLKSPIRCIVCGMETESDSAVTLSIDNASIILTATVIGYCRDPSDAVNQIRKESLRACTKHFNSIFHVIFEGLQIENTYCAHHAKYSLANRWCKVYTMIRSSLGEQFTKFDVRNFKSILQSFLDTFGEIDDDKKDKESSHFDECFEEMDSENVEIKMESPQEEAAEKSKFSENLVEVKLEPIETHELDKTISDFSSSDIIDSSQKLQQNGFPEKVEQMDKYSNKLKDEASDKKYEKPGKKDYVEEEGYWAPITDSEDDEA
What is the function of this protein?
Required for translation, stability and/or localization of lin-15a.
What are the official names of this protein?
Protein lin-56, Abnormal cell lineage protein 56.
Protein: Y1643_CHLL3
Sequence: MSGHSKWATIKRKKAVTDQKRGSLFTKLVKEITIAAKMGGGDPSGNPRLRLAIDTARSNSMPMDNIQRAVKKGTGELEGVIYDEITYEGYGPAGIALIIETATDNRNRTVADLRHIMSRNNGSLGESGSVSWMFQRKGSLEVPVSAASEEALMEALLEAGLEDLSNDGGETYTVITDVRDLEAAKKALEEQAIAFENAKMDLIPENYIELEAEDARKVIKLIDALEENDDVQAVYSNMEISESAMNSLED
What are the official names of this protein?
Probable transcriptional regulatory protein Plut_1643.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC7_YEAST
Sequence: MSKTAQKRLLKELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGPPDTPYADGVFNAKLEFPKDYPLSPPKLTFTPSILHPNIYPNGEVCISILHSPGDDPNMYELAEERWSPVQSVEKILLSVMSMLSEPNIESGANIDACILWRDNRPEFERQVKLSILKSLGF
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system.  Cognate E2 conjugating enzyme for the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M).  Involved in resistance to cadmium poisoning.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 7, E2 ubiquitin-conjugating enzyme 7, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-18 kDa, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Anchored via the membrane protein CUE1 to the endoplasmic reticulum membrane.
Protein: CYB_CEPJE
Sequence: MTNIRKTHPLMKIVNSAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTYTETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILALMILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAGP_PANAA
Sequence: MNRYLLTTLSAPLLALFFSFSLQAAMLSQEIKSGWDTFTGNVQQTWQQPDAIDVYVPAITWHNRWTYDEEHIHRYNERPWGAGGGVSRYDEKGNWHGLYLMAFKDSFNKWEPFGGYGWEATWRPLQDQNFHYGLGYTAGVTARHNWGYYPVPAILPLASIGYGSLNFQMTYIPGTYNNGNVYFAWLRWQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: YPDA_GEOSE
Sequence: EFRFVRWHDVSTDVLPAGGSKAEGIRLMIEKLGIDKGDVYAFGDGLNDIEMLSFVGTGVAMGNAHEEVKRVADFVTKPVSEEGIWHGLKQLQLIP
What are the official names of this protein?
Uncharacterized protein in pdhA 5'region, ORF1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: GPMI_THIDA
Sequence: MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMGNSEVGHLNIGAGRVVYQEFTRIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDGGVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSAELYLRRLTDKIAQAGVGHVASMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIVPADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDDFDVSVAFPPERIKNGLGEYVANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVSSPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYANPDMVGHTGNLEAAIKAIETVDTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLAETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: ABCD2_HUMAN
Sequence: MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAAENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS
What is the function of this protein?
ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen (PubMed:21145416, PubMed:29397936).  Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (Probable) (PubMed:29397936).  Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro) (PubMed:21145416).  Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:21145416).
What are the official names of this protein?
ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: AHPC_HELPY
Sequence: MLVTKLAPDFKAPAVLGNNEVDEHFELSKNLGKNGAILFFWPKDFTFVCPTEIIAFDKRVKDFQEKGFNVIGVSIDSEQVHFAWKNTPVEKGGIGQVTFPMVADITKSISRDYDVLFEEAIALRGAFLIDKNMKVRHAVINDLPLGRNADEMLRMVDALLHFEEHGEVCPAGWRKGDKGMKATHQGVAEYLKENSIKL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, 26 kDa antigen, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y003_HIS1I
Sequence: MSVEYGPNHDFLCACNTYHRKPNIKITAVVFGTTKERLVCSECLTFIIENLEIQNGQLCIQEVKRFWQAGKFAWEKQSEL
What are the official names of this protein?
Uncharacterized protein ORF3.
Protein: FNDC7_HUMAN
Sequence: MAGGRETCLPLIGFILICLKMVASAKSAPEIPTIDQAYSKLSNSITVEWATVPGATSYLLTAEDGDTVIETTVANSPGTVTGLKAATWYEITIRSISAAGRSQASPPKQAKTVLAAPILEVSSPSSDSILVQWEAVYMAIAFSVSIMRANGLGSIWKENTTNTSLTFTSLEAGTLYTIKAYAWNANRIPGDDSTCNQRTSPRAPANIQVSFDSGALKASFSWARAEGAFNYTVMALSDSSELTCSTTFSSCTISSLQCGTEYLISVLASNDAGSSKSSSAMTLKTVACAPGRVTIQEDPPGHLSVAWSSVDLGDYYVVFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFVYNKAGQSPLGDIFNYTTAPCCPSDINPVLVSSDRVEIVWSPVRGAELYETKAVDGYNMVECNDTTPACTLSALECDTKYNITVYSFNEVRGSNMSCTPQFITTAPCSPEIKNVSRDAFSMINVHWRSTNDDATYTVTAQGEKGLYQCSSTGESCTMRGLPCGSVFSVTAVAETQAGRSLPSYSVPLETVPCCPTGLTVTQITQSVINVSWTIGRVAQTHVAVLESHTGQSKCHTHQNHCLLGCITCGINYTVTLKAISATGLTADCSYQSYFSGACCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCTPSAGLSFCDVTEIPCGDVYTVMVSPVAKTGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNEE
What are the official names of this protein?
Fibronectin type III domain-containing protein 7.
What are the subcellular locations of this protein?
Secreted.
Protein: RHAT_CROS8
Sequence: MSNAITMGILWHLIGAASAACFYAPFKKVRHWSWETMWSVGGVVSWLILPWVVSALLLPDFWAYYRSFSAATLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPLLNGKFGVLVGTAGGRMTLLGVFVALVGVAIVTRAGQLKERQMGIKAEEFNLKKGLVLAVLCGVFSAGMSFAMDAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALINLGFCFIRLAKVKNLSIKADFSLAKPLLISNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLLLREWKTAGRRPVSVLSLGCVVIIVAANIVGLGMATN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_LEGPC
Sequence: MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSGKMNLSLKDVNGGLLLVPQFTLMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNTQSGCFGANMQVYLCNDGPVTFLLQF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_RHILW
Sequence: MNDKTENTLSSDVTEVRAQKLKLLREQVGDVYPAHFHRTLTNAELGAKYESLESDVETQDVVTVAGRVYSSRNSGMFMDIHDASGKIQIFSHKDTTPEEARALLPMIDIGDIIGVTGIVRRTKRGELTINAQKIEMLTKSLLPMPEKWHGLSDIELRYRKRHLDIMTNEDSKLRFQQRSKIVSGIRRFMENDGFMEVETPMLQSIYGGATAEPFKTHHNTLKLDMYLRIAPELFLKRTLVSGLTDKVFEINRNFRNEGVSTRHNPEFTMMECYWAYADYEDMMDLVERLFETLALSIHGTTEFDFGDKQLSFKGPFKRVPMPDAVKQVTGIDFLAIKTDEEARTAAKAAGFAVEKDWTWGECLAFIFEEKVESTLIQPSHVTHFPKDISPFAKEVPGEPRLVERFETYCNAWELGNAFSELNDPEEQRRRMVEQLEQAHARGEKEKQLDEEFLDAIDQGMPPAGGLGIGVDRLIMLLTNAPSIRDVILFPARRNKAD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHA1_HUMAN
Sequence: MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
What is the function of this protein?
Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides.  May recruit other proteins to the plasma membrane.
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 1, PH domain-containing family A member 1, Tandem PH domain-containing protein 1, TAPP-1.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.
Protein: NIFH_MARSD
Sequence: MRKVAIYGKGGIGKSTTTQNTVAGLATMDRKVMVVGCDPKADSTRLLLGGLAQKSVLDTLREEGEDVELEDIRKPGFGESWCVESGGPEPGVGCAGRGIITSINMLENLGAYEEGENLDYVFYDVLGDVVCGGFAMPIRDGKAEEIYIVCSGEMMAMYAANNICKGIMKYAESGGVRLGGLICNSRNVDNEKEMIEELAKKLGTQMIYFVPRDNDVQRAEINRKTVIEWDDTVPQADAYRGLAEAIDKNEMFVVPTPLEIEELEQLLLDYGLMEA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: SYC_SOLUE
Sequence: MALRFYNTLSQQVEEFTPASDNTVRMYTCGPTVYDFAHIGNFRTFTFVDLLRKVLRANGFQLNHVMNITDVDDKIIRNAVAQHQSLEQYTKIYTEAFLEDCKMLRLERPERIAPATEHIHDMVSAIERLGDSQHTYASDGSVYFKIASFPGYGKLSHNDFSGNLAGARVDVDEYEKADARDFALWKTPKEGEPFWDTTIGPGRPGWHIECSVMAIKYLGETLDIHAGGIDLVFPHHENEIAQSESLTGKLFSRFWLHAEFLMVEGQKMSKSLGNYYTLRDLVAKGYEPESIRYLLASVPYRKSLNFTLDGLKAARIAIERLRNFKRRLETEPFAEGLSAILAERTAQASQAFIGGLNEDLNTAEALASVFEYVRDLNSAMDSGEFRAGNTTAALEFLARFDSIFDVLKPTAKAGELSDAEIDAQIAARAAAKKSRDFALADQIRDQLLAQGIILEDTKSGVRWKRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_CORGL
Sequence: MCGIVGYIGQAGDSRDYFALDVVVEGLRRLEYRGYDSAGIAIHANGEISYRKKAGKVAALDAEIAKAPLPDSILGIGHTRWATHGGPTDVNAHPHVVSNGKLAVVHNGIIENFAELRSELSAKGYNFVSDTDTEVAASLLAEIYNTQANGDLTLAMQLTGQRLEGAFTLLAIHADHDDRIVAARRNSPLVIGVGEGENFLGSDVSGFIDYTRKAVELANDQVVTITADDYAITNFDGSEAVGKPFDVEWDAAAAEKGGFGSFMEKEIHDQPAAVRDTLMGRLDEDGKLVLDELRIDEAILRSVDKIVIVACGTAAYAGQVARYAIEHWCRIPTEVELAHEFRYRDPILNEKTLVVALSQSGETMDTLMAVRHAREQGAKVVAICNTVGSTLPREADASLYTYAGPEIAVASTKAFLAQITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMADAKSVLFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPIFVIVPSPRGRDSLHSKVVSNIQEIRARGAVTIVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIFACAVATAKGYNVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCTT_MYCS2
Sequence: MSSETSSESTGHRPVLLVFADSLSYFGPTGGLPADDPRIWPNIVGEQLGWDVELIGRIGWTCRDVWWAATQDPRSWAALPRAGAVVFATSGMDSLPSPLPTALREMIRYVRPPWLRRWVRDGYGWVQPRLSPIARSALPPHVTVEYLEMTRNAIDFNRPGIPVVASLPSVHIAETYGRAHHGREPTVRAITAWAEEHHVPLVDLKAAVADEVFGGRGNPDGIHWSFEAHRAVAELMLKGLAEAGVTQRDSAT
What is the function of this protein?
Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP).  Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG).  DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate.  DGG and GG are the two earliest intermediates in MGLP biosynthesis.
What are the official names of this protein?
Diglucosylglycerate octanoyltransferase, DGG octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the OctT acyltransferase family.
Protein: ATF6A_RAT
Sequence: MESPFSPVLPHGPGEDWESTLFAELGYFTDTDDVQFDAAHETYENNFDHLNFDLDLMPWESDIWSPSSHFCSDIKAEPQPLSPASSSCSVSSPRSTDSCSSTQHVPEELDLLSSSQSPLSLYGDSCHSPSSAEPLKEEKPVTGPGNKTEHGLTPKKKIQMSSKPSVQPKPLLLPAAPKTPANASVPAKTIIIQTLPALMPLAKQQSIISIQPAPTKGQTVLLSQPAVVQLQTPGVLPSAQPVLAVTGGATQLPNHVVNVVPAPVVNSPVNGKLCVTKPVLQSSTRSTGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGSLKRQLDQVVSENQRLKVPSPKRRAVCVMIVLAFIMLNYGPMSMLEQDSRRVKPSVSPANQRRHLLEFSAKEVKDTSDGDNQKNSYRYDHSVSNDKALMVLSEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNSQQKTRILQGALEQGSNSQLMAVQYTETTSISRNSGSELQVYYASPGSYQGFFDAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININDNVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDHQRNQTSTFFGSPPTATETTHVVSTLPESVQ
What is the function of this protein?
Transcription factor that initiates the unfolded protein response (UPR) during endoplasmic reticulum stress by activating transcription of genes involved in the UPR.  Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3').  Binding to ERSE requires binding of NF-Y to ERSE.  Could also be involved in activation of transcription by the serum response factor.  May play a role in foveal development and cone function in the retina.
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha, Activating transcription factor 6 alpha, ATF6-alpha.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Translocates from the endoplasmic reticulum to the Golgi, where it is processed. SUBCELLULAR LOCATION: [Processed cyclic AMP-dependent transcription factor ATF-6 alpha]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus (PubMed:22682248). THBS4 promotes its nuclear shuttling (By similarity).
Protein: MQNE_THET8
Sequence: MRGIRDPRLIPIAEKVMEGKRLSFEDGLVLYQTKDLPTLMRLANLVRERKHGHKTYFVHSIRVSQTNICYVGCTFCAFQRRFGEEGAWDWDVDEVVAWVKERYQPGLTEIHLTAGHHPKRPFAYYLDLVRALKENFPGVQVKAWTAAEIHHFSKIARLPYREVLKALKEAGLDAMPGGGAEIFAERVRRKIARAKVSAEGWLEIHRTAHELGIPTNATMLYGHIETLEERLDHMDRLRRLQDETGGFMSFIPLAFQPDGNQLARELGKKEFTTGLDDLRNLAVARLYLDNFPHIKGYWATLTPELAQVSLDWGVTDVDGTLIEERIVHMAGSPTPQGLTKRELARIILMAGRIPVERDALYREVRVWDRVEA
What is the function of this protein?
Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
What are the official names of this protein?
Aminodeoxyfutalosine synthase, AFL synthase, Aminofutalosine synthase, Menaquinone biosynthetic enzyme MqnE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MqnE family.