PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_SYNP6
Sequence: MAAAILDGRALAAQRRQQLREQVEAIAPAVGRRPGLAVIMVGDNPASAVYVRNKERACEQTGIVSFGKHLPGDSSEAEIRALIEELNQDDRVDGILVQLPLPSHLDAVPLLLAIDPEKDADGLHPLNLGRLLRGEEGLRSCTPAGVMELLAANQIDPAGKKAVVIGRSILVGKPLAMMLLEANATVTIAHSRTPNLPEVCRQADIVVAAVGRPELVGADWIKPGAVVVDVGINRLEDGRLVGDVDYEAASAITSWITPVPGGVGPMTVAMLLHNTVLSYCRRSGQPFLS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GCH3_METMP
Sequence: MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHKGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATKTIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQKTKLKLMEELKKYDSLGFFIGGDNFMCPCNGMNEKDFLCMFEDIKDSCGIELKAGIGIGKTAEDASNLADIGLEVIREGKTDSQVYTLKQEIDEQKNVPYNYMCPI
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: PHO85_ASHGO
Sequence: MTSTSQFKQLERLGNGTYATVYKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKFMDSRLDREMPRGLELSLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYCTSIDIWSCGCILAEMIMGKALFPGTNDDEQLKLIFETMGTPTEQTWVGVSQLPKYNPQIPLYPNKDIKQLLQATTKEQISDVLVNLIQGLLQLNPSMRLSAQQALSHPLFEEYH
What is the function of this protein?
When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.
What are the official names of this protein?
Negative regulator of the PHO system, Serine/threonine-protein kinase PHO85.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: SCP2_RAT
Sequence: MPSVALNSPRLPRVFVVGVGMTKFMKPGGENSRDYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGESTCGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKGSLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQKHGLQSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAAVVTLYRMGFPEAASSFRTHQISAAPTSSAGDGFKANLIFKEIEKKLEEEGEEFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPDSDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGNMGLAMKLQSLQLQPDKAKL
What is the function of this protein?
Mediates the transfer of all common phospholipids, cholesterol and gangliosides from the endoplasmic reticulum to the plasma membrane.  May play a role in regulating steroidogenesis (By similarity).  Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol (PubMed:8063752).  Also binds fatty acids and fatty acyl Coenzyme A (CoA) such as phytanoyl-CoA.  Involved in the regulation phospholipid synthesis in endoplasmic reticulum enhancing the incorporation of exogenous fatty acid into glycerides.  Seems to stimulate the rate-limiting step in phosphatidic acid formation mediated by GPAT3 (PubMed:9553048) (By similarity).  Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs (PubMed:9553048).
What are the official names of this protein?
Sterol carrier protein 2, SCP-2, Acetyl-CoA C-myristoyltransferase, Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-2/3-oxoacyl-CoA thiolase, SCP-2/thiolase, SCP-chi, Sterol carrier protein X, SCP-X.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
[Isoform SCP2]: Peroxisome. Cytoplasm. Mitochondrion. SUBCELLULAR LOCATION: [Isoform SCPx]: Peroxisome.
Protein: MO2R2_MOUSE
Sequence: MHALGRTPALTLLIFIYNFVSVYTIVSVQMGTKARLCCRSIPLTKAVLITWIIKPRGQPSCIMAYKVETKETNETCLGRNITWASTPDHIPDLQISAVALQHEGNYLCEITTPEGNFHKVYDLQVLVPPEVTYFLGENRTAVCEAMAGKPAAQISWTPDGDCVTKSESHSNGTVTVRSTCHWEQNNVSAVSCIVSHSTGNQSLSIELSRGTTSTTPSLLTILYVKMVLLGIILLKVGFAFFQKRNVTRT
What is the function of this protein?
According to PubMed:15187158 it is a receptor for the CD200 cell surface glycoprotein.  According to PubMed:16081818 it is not a receptor for the CD200/OX2 cell surface glycoprotein.  Involved in the recruitment or surface expression of the TYROBP receptor.
What are the official names of this protein?
Cell surface glycoprotein CD200 receptor 2, CD200 cell surface glycoprotein receptor-like 2, CD200 receptor-like 2, CD200 cell surface glycoprotein receptor-like c, CD200RLc, Cell surface glycoprotein OX2 receptor 2.
What is the protein family that this protein belongs to?
Belongs to the CD200R family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DRMA_BACP9
Sequence: MSKAEREMYKKVRRIMVSDLKRDLIGPAHDESDVIYEAPSQAYITGILYPLESEVETEKSLEDVQFADVYDEPESGMEEDVEQQRNSELEQEAEEEKITPNKKFKHQNSLGIRCYVRETTDHIRASIAWGRYTSSKKFDSERKREVILWTRQIECFEEYISLSSFDQNIDIPITQEVSLVVSKKKLSGTDVFLVSVFLVNKRVDKNSNNAMFQCELTLTHEEGKGIFLCENEARKDKNDFSEFLYRNKPVFAKGFGCAVTWKAESSNYASELKSAFIPEHEVESMSTDLPYDENYGELPKGYFSIKQFAEADDQRETIDKLNNLANRYESWINKLPVDKVANKEATERVIKDCQATLTRIRRGIQLLANEENNKAFVAFKFMNTVMHTQDAMKRYSRNNKTTTLETEIRKENLEWRPFQLAFILLNLEGLVDLKSKDRKIVDLLWFPTGGGKTEAYLGICAFLLGYRRLFASTSSAYERDGGVTILLRYTLRLLTTQQRDRLMRMISACEYTRQKTNAFGQSEFSVGFWVGAQVTVNKLDDLTENEYYLDRDKVLKEYEKIEKQVIECPCCGTKGLEYKFLPSRDTKTKKTGIKIFCTNESCFFSKTHIPVYLVDEEIYRKLPTVVISTVDKFARLPWDEKTAALFGKVNRFCERCGYIAEGEKHEKSHRNPKASVHDVKPFYPPELIIQDELHLITGPLGTVYGGYETVIEELSTAHEGEDYLKPKYIAATATIKNAEVQVEKVFGRKLTQQFPPPGLKVEDSFFARERNLDEFPFRLYAGVCVSGHSMKTVLLRIYAVLLQTTEHLLEDEELSKYIDPYRTLVGYFNSIRELGGAVRLLEDDIKKRIQTLQKKYKYSKQRYISRKPELTSRVPSSRIPKVLEQLEKEIGNEELDVVLATNMISVGMDVDRLGLMVITGQPKQTSEYIQSSSRVGRSKPGLVITVYNPYRPRDMSHYQNFKGYHQRLYHFVEGTTATPYASRARDRFLHAIAVALLRLSYPELAKNLDAKNIKDMDLNYLKDVVKKRVSTVEYRNVSDTMEHLQHFLDEWISRAVSEDNLQYYFNPKTRSARIGNQSRLLARFSEEKKHGGKPTLDSMRQVEGTSSLYIYEGWNSSEE
What is the function of this protein?
Component of antiviral defense system DISARM (defense island system associated with restriction-modification), composed of DrmE, DrmA, DrmB, DrmC and DrmMII.  DISARM is probably a multi-gene restriction module, this subunit is probably a helicase.  Expression of DISARM in B. subtilis (strain BEST7003) confers resistance to phages Nf, phi29, phi105, phi3T, SPO1, SPR and SPP1.  Protection is over 10(7)-fold against phi3T, 10(4)-10(5)-fold against Nf, phi29, phi105 and SPR, 100-fold against SPO1 and 10-fold against SPP1.  DISARM does not interfere with phage adsorption, but instead interferes with (phi3T) DNA replication early in its cycle, preventing replication, circularization and lysogeny and probably causes phage DNA degradation (DNA is degraded in SPP1-infected cells).
What are the official names of this protein?
DISARM protein DrmA, Probable ATP-dependent helicase DrmA.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_SHIF8
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GMHA_LEPBP
Sequence: MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASHIAAELVIRYKSGNERKAIPAIALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGLTTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADVEIIIPSSVTARIQESHILIGHILCSIIEKELFGLD
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_OENEH
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HUTH_BACC7
Sequence: MITLTGHTLTIEEMKRLLLEGEGVTACPNSMQKVAECREVVEKIVEDGKVVYGITTGFGKFSDVLIQKDDVKALQHNLIQSHACGIGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLEFVNRKIHPVVPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMVALTEEGLEPIELEAKEGLALINGTQAMTAQGVLSYIEAEATAYQAEFIASMTIEGLQGIIDAFDENVHKARGYKEQVEVASRIRDILHDSKLTTKQGELRVQDAYSLRCIPQVHGASWQVLNYVKEKLEIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAELANISERRIERLVNPQLNDLPPFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLSIEMICAMQAAEYRGIENMSTVTKSFYHQGRQQVPSITNDRIFSTDIENIAYWLKTNYSIKERLDVNAAL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_DICNV
Sequence: MTTYSFTEKKRIRKNFSKRPTVLETPYLLSMQIDSYNDFLQQHVPMQSRAKKGLQEAFESIFPIKSHNEMVELQFVGYEFGKPEFDVRECQLRGVTYAAPLRVRMRLAIYDKNSTKKKLKQVVESESVYMGDIPLMTDDGTFVINGTERVIVSQLHRSPGVFFGDDDGQGHSSGKKLYNARIIPYRGSWLDLEFDVKDLIYCRIDRRRKLLITILLRALGLSNQEMLDIFFSKQTFKLNKTGKIELVFEPEQFAGELAQFDIIADGEVIVPMGRKISSRFVRQLIEKKVKKQTVPVDFVVGKFLATDLVDKETGELILAANSELTEELLTRFVELGVKEFQTLLINENGHGGYLADTLRLDETTTELEARAEIYRMMRPGEPPTKEAADSLFEGLFFDEARYDLSRVGRMKFNRSLGREESEGSGILSKEDIIGVVKKLIAIKDGFGSTDDIDHLGNRRIRSVGEMAENAFRIGLVRLERTVKERLAQAESEGLTPKDLINVKPVGAAVKEFFSSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLAVYARTNEYGFLETPYRKVIDGKVTDEIEYLSAIDESKYVIAQANAHLDEHGAFMDGLISTRFENEFTLMPSSRVQYMDVSPRQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERVVAMDSGVLVKAARGGVIDSVDSSRIVVKVNDDEVQAGGLGVDIYNLTKYTRSNQNTCINQKPLVSPGDIVARGDVLADGPSTDMGELALGQNVLVAFMPWNGYNYEDSILISERVSQEDRFTTIHIEELTCIARDTKLGPEEISSDIPNVKESALAKLDTTGIVYVGAEVKFGDILVGKVTPKGERSQSPEEKLLRAIFGEKASDVKDSSLRVPTGMDGTVVDVRVYTRDGIEKDERAKAIEKMEIDSIAKDIKDQLRIFSADIHDRAARLLLGQAIKKAPKRKSGDTVDQALLDETTPEQWFDFRMQDEAINEKLDAMKQLLEDKHKELQDYYEEKKAKFSQGDDLAPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSLVVPVEDMPYMEDGTPVDIVLNPLGVPSRMNIGQVLELHLGWAAAGLGKRLAQMMDEGAPIKELRRYLDAVYNHNPACKKEDLDALSDEDFWQLCRNLRQGIPMATPVFDGAEEVEDLQKMLELAELPATGQTHLYDGRTGERFDREVSVGYMYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGRAQFGGQRFGEMEVWALQAYGASYTLQEMLTVKSDDVDGRTKMYKNIVDGNLKIEPGLPESFNVLTKEIRALGIDIGLTQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ISPD_ENT38
Sequence: MAVTISDVCAVVPAAGFGRRMQTECPKQYLSIGDKTILEHTVAALLANPRVTRVVIAISPGDARFAALPLANHPQITVVDGGTERADSVLAGIRAAGNVAWVLVHDAARPCLHPDDLARLLAISQTSTVGGILAAPVRDTMKRAEPGLNHIAHTVERVDLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPELVEGRADNIKVTRPEDLQLAEFYLTRMTYQENA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: KTHY_UREP2
Sequence: MILTKNSNEKKPLKKGLFIVFEGIDGAGKTSILKQLLEVLKEPKLVNKIFLTREPGGKNNNAAEMIREFFLKNLEVFDPLTLAYLYASSRAEHVKKTINPHLEKDHIVISDRFVHSSYIYQGIVQNQSLDVIYQINQQAIGELEIDYVFYFDVNVNNALNRMKNRFDNTNAFDSQNKQFYEKLLKQYPSVFKVYNQPKKIIFIDANKNENEVLCEVKEQLLKIFKEHKYI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CMOB_SODGM
Sequence: MSQFADFYQLIAKSPLSHWLNTLPAQLSEWEQTSQHCKFSQWFNAVERLPMLTPARLDLLHGVEADCDPPLSAGQQAGIESLLRQLMPWRKGPFSLYGVSIDTEWRSDWKWERVLPHIAPLAGRLILDVGCGSGYHLWRMVGAGAQLAVGIDPMQLFYCQFAAVRKLLGGDQRAHLLPLGIEQLPALAAFDTVFSMGVLYHRRSPLDHLLQLKNQLVSGGELVLETLVIEGDSQQVLVPGERYAQMRNVYFIPSATALVSWLEKCGFVNVRHVDMSVTSTDEQRRTAWMTSESLADFLHSDDPRLTVEGHPAPLRAVIVAEKH
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RNPA_STACT
Sequence: MEKAYRIKKNSDFQAIYRRGKSVANRQFVIYMMPDKGLTHFKLGISVSKKLGNAVTRNRIKRAIRENFKVHKDDMLPRNIIVIARHPAKDMTVLEIQKSLEHVLKVAKLFNKRIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: M3K17_ARATH
Sequence: MEWTRGRILGRGSTATVYAAAGHNSDEILAVKSSEVHRSEFLQREAKILSSLSSPYVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDILKGLEYIHSKGIVHCDVKGSNVVISEKGEAKIADFGCAKRVDPVFESPVMGTPAFMAPEVARGEKQGKESDIWAVGCTMIEMVTGSPPWTKADSREDPVSVLYRVGYSSETPELPCLLAEEAKDFLEKCLKREANERWTATQLLNHPFLTTKPDIEPVLVPGLISNSPTSVTDQTFWRSVEEEEEEETEEIQKDSRDLDRLSLWGCYSERIGRLKCVGGLDGTRCDMEGGDWIMVRARCEGTMISGSQKELIISENVLVGEL
What is the function of this protein?
Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses.  Triggers MPK7 activation in a MKK3-dependent manner.  Mediates the ABA-dependent activation of the MKK3-MPK7 module.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRG11_RALSO
Sequence: MRIGKSSGWLNESVSLEYEHVSPPTRPRDTRRRPRAAGDGGLAHLHRRLAVGYAEDTPRTEARSPAPRRPLPVAPASAPPAPSLVPEPPMPVSLPAVSSPRFSAGSSAAITDPFPSLPPTPVLYAMARELEALSDATWQPAVPLPAEPPTDARRGNTVFDEASASSPVIASACPQAFASPPRAPRSARARRARTGGDAWPAPTFLSRPSSSRIGRDVFGKLVALGYSREQIRKLKQESLSEIAKYHTTLTGQGFTHADICRISRRRQSLRVVARNYPELAAALPELTRAHIVDIARQRSGDLALQALLPVATALTAAPLRLSASQIATVAQYGERPAIQALYRLRRKLTRAPLHLTPQQVVAIASNTGGKRALEAVCVQLPVLRAAPYRLSTEQVVAIASNKGGKQALEAVKAHLLDLLGAPYVLDTEQVVAIASHNGGKQALEAVKADLLDLRGAPYALSTEQVVAIASHNGGKQALEAVKADLLELRGAPYALSTEQVVAIASHNGGKQALEAVKAHLLDLRGVPYALSTEQVVAIASHNGGKQALEAVKAQLLDLRGAPYALSTAQVVAIASNGGGKQALEGIGEQLLKLRTAPYGLSTEQVVAIASHDGGKQALEAVGAQLVALRAAPYALSTEQVVAIASNKGGKQALEAVKAQLLELRGAPYALSTAQVVAIASHDGGNQALEAVGTQLVALRAAPYALSTEQVVAIASHDGGKQALEAVGAQLVALRAAPYALNTEQVVAIASSHGGKQALEAVRALFPDLRAAPYALSTAQLVAIASNPGGKQALEAVRALFRELRAAPYALSTEQVVAIASNHGGKQALEAVRALFRGLRAAPYGLSTAQVVAIASSNGGKQALEAVWALLPVLRATPYDLNTAQIVAIASHDGGKPALEAVWAKLPVLRGAPYALSTAQVVAIACISGQQALEAIEAHMPTLRQASHSLSPERVAAIACIGGRSAVEAVRQGLPVKAIRRIRREKAPVAGPPPASLGPTPQELVAVLHFFRAHQQPRQAFVDALAAFQATRPALLRLLSSVGVTEIEALGGTIPDATERWQRLLGRLGFRPATGAAAPSPDSLQGFAQSLERTLGSPGMAGQSACSPHRKRPAETAIAPRSIRRSPNNAGQPSEPWPDQLAWLQRRKRTARSHIRADSAASVPANLHLGTRAQFTPDRLRAEPGPIMQAHTSPASVSFGSHVAFEPGLPDPGTPTSADLASFEAEPFGVGPLDFHLDWLLQILET
What is the function of this protein?
Exported into plant cells, where it is targeted to the nucleus and probably acts as a transcription factor.  Binds DNA in a sequence-specific manner.  May contribute to plant pathogenicity.
What are the official names of this protein?
TAL effector protein Brg11.
What is the protein family that this protein belongs to?
Belongs to the transcription activator-like effector (TALE) family. RipTAL/RTL subfamily.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Secreted via type III secretion system (TTSS).
Protein: DPCKG_METMA
Sequence: MSVHIELPRELRPLMKKPLGILYRGKGRDTIEKFAGELSSPTKLISVGDVTTFHLLEAGIIPDICIVDDRTKRKPVSSDVSVRNRDKVYEEVSVDNPAGIITDELIRTLCEAFASEKLLRIFVRGEEDLATLPVILLAPPGSVVLYGQPDEGVVFVEVTEKKKEEIRALFEKLISKNQNNELDKIRRILDGHKDN
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: RNPA_SALA4
Sequence: MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: H2BV3_DICDI
Sequence: MVFVKGQKKATKGSTQSGEEKTASTTPKVTKTPTEGGEKKRKKRKSDYTSFSTYIHKLLKQITPPTNAKSNEKGDRKFTISSKAMSVMNSFVHDIFDRIATEASGLAKKKKRQTLHSRDIQVAVRIILTGELAKHAILQGMTAVNKYNPTESKN
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H2B.v3.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ARGR_ENT38
Sequence: MRSSSKQEELVKAFKALLKEEKFSSQGEIVLALQEQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKSEGILGTIAGDDTIFTTPANGFSVKDLYEAILMLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PROMM
Sequence: MTKPALRSDIPMKPTVHKQEKPSVAFAHLGCEKNRVDTEHMLGLLTEAGYSVSSDENDAAVVVVNTCSFIQDAREESVRTLIGLAEQGKELIIAGCLAQHFQEELLESIPEAKAIVGTGDYQHIVDVLKRVEAGERVNHVSEFPTFVGDETLPRQRTTDQAVAYLKVAEGCDYRCAFCIIPKLRGDQRSRPVESIVTEAHQLAEQGVQELILISQITTNYGLDLYGKPKFAELLQALGEVDIPWVRVHYAYPTGLTPEVLAAYREVPNVLRYLDLPLQHSHPEVLRAMNRPWQTDVNERLLDRIREQLPDAVLRTTLIVGFPGETEDHFNHLAAFIERQRFDHVGVFTFSPEDGTAAADLPDRVDPSIAAARKDRLMALQQPISAERNQRWVGRTIDVLIEQHNPETGAMIGRCDRFAPEVDGEVLVLPSEKGLQASPGTMVPVFITGSDVYDLTGQLVDTNAMAVTAQTSQ
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_THEP3
Sequence: MRAVVQRVSRGEVSVGGEMVSSIGKGFVVLVGISIDDNENDVMYMADKIVNLRVFEDEEGKMNLSLLDIGGEVLLVSQFTLLGDVRKGRRPNFMMAQKPQEALKYFNLLVKEIEKRGVSVKTGIFQAMMKVLIENDGPVTILIDSKKVF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXL16_RAT
Sequence: MSSPGIDGDPKPSCLPRNGLVKLPGQPNGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLATPLSRVALAGGPCPPASGPASGPVPGPPVERPPLATDEKILNGLFWYFSACEKCILAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRSLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box/LRR-repeat protein 16, F-box and leucine-rich repeat protein 16, Spinal cord injury and regeneration-related protein 1.