PharMolix/UniProtQA huggingface dataset:
Protein: IF2P_SULTO
Sequence: MSQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIEKIAEPLKKTFPIKLEIPGLLFIDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYESLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQRKDVQTQLDNYVYRLVGQLAELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKGVILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKTDLTQIDEVYAAAGVKIYAPELENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANIAGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDITEAELTLQEAKEYGIIAAFRVKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYVFRRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKGNIMVGRQIDEGEILYTDVPKEDLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGLKV
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: LGB6_PEA
Sequence: MGFTEKQEALVNSSWELFKQNPSYSVLFYTIILKKAPAAKGMFSFLKDSAEVVDSPKLQAHAEKVFGMVHDSAIQLRASGEVVLGDATLGAIHIQKGVVDPHFVVVKEALLETIKEASGEKWSEELSTAWEVAYEGLASAIKKAMN
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin Lb120-34.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: NEPU2_THEVU
Sequence: MLLEAIFHEAKGSYAYPISETQLRVRLRAKKGDVVRCEVLYADRYASPEEELAHALAGKAGSDERFDYFEALLECSTKRVKYVFLLTGPQGEAVYFGETGFSAERSKAGVFQYAYIHRSEVFTTPEWAKEAVIYQIFPERFANGDPSNDPPGTEQWAKDARPRHDSFYGGDLKGVIDRLPYLEELGVTALYFTPIFASPSHHKYDTADYLAIDPQFGDLPTFRRLVDEAHRRGIKIILDAVFNHAGDQFFAFRDVLQKGEQSRYKDWFFIEDFPVSKTSRTNYETFAVQVPAMPKLRTENPEVKEYLFDVARFWMEQGIDGWRLDVANEVDHAFWREFRRLVKSLNPDALIVGEIWHDASGWLMGDQFDSVMNYLFRESVIRFFATGEIHAERFDAELTRARMLYPEQAAQGLWNLLDSHDTERFLTSCGGNEAKFRLAVLFQMTYLGTPLIYYGDEIGMAGATDPDCRRPMIWEEKEQNRGLFEFYKELIRLRHRLASLTRGNVRSWHADKQANLYAFVRTVQDQHVGVVLNNRGEKQTVLLQVPESGGKTWLDCLTGEEVHGKQGQLKLTLRPYQGMILWNGR
What is the function of this protein?
Hydrolyzes pullulan efficiently but only a small amount of starch.  Endohydrolysis of 1,4-alpha-glucosidic linkages in pullulan to form panose.  Cleaves also (1-6)-alpha-glucosidic linkages to form maltotriose.
What are the official names of this protein?
Neopullulanase 2, Alpha-amylase II, TVA II.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: HSLV_CAMJJ
Sequence: MFHATTILAYKGKNKSVIGGDGQVSFGNTVLKGNAVKIRKLNNGKVLAGFAGSTADAFNLFDMFENLLQSSKGDLLKAAIDFSKEWRKDKYLRKLEAMMLVLDRNHIFLLSGTGDVVEPEDGQIAAIGSGGNYALSAARALAKHASLDEEELVKSSLQIAGEICIYTNTNIKTYVIEDEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SALCH
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDLKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PIN1_MACFA
Sequence: MADEEKLPPGWEKRMSRSSDRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
What is the function of this protein?
Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs.  By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes.  Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized.  Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity.  Down-regulates kinase activity of BTK.  Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation.  Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.  Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.  Acts as a regulator of JNK cascade by binding to phosphorylated FBXW7, disrupting FBXW7 dimerization and promoting FBXW7 autoubiquitination and degradation: degradation of FBXW7 leads to subsequent stabilization of JUN.  May facilitate the ubiquitination and proteasomal degradation of RBBP8/CtIP through CUL3/KLHL15 E3 ubiquitin-protein ligase complex, hence favors DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR).  Upon IL33-induced lung inflammation, catalyzes cis-trans isomerization of phosphorylated IRAK3/IRAK-M, inducing IRAK3 stabilization, nuclear translocation and expression of pro-inflammatory genes in dendritic cells.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Colocalizes with NEK6 in the nucleus. Mainly localized in the nucleus but phosphorylation at Ser-71 by DAPK1 results in inhibition of its nuclear localization.
Protein: GLYA_BORPE
Sequence: MFNRNLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRLKQIFGAEAANVQPNSGSQANQGVYMAVLKPGDTVLGMSLAEGGHLTHGASVNASGKLYNFVPYGLDADEVLDYAQVERLTKEHKPKLIVAGASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGPRGGVIMMKAEFEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLIADVLDNPRDEANIAAVRARVNELTARLPVYGN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ACIF5
Sequence: MAHKKAGGSSRNGRDSESKRLGVKRYAGQEVISGNIIIRQRGTQFYPGANVGIGKDHTLFATAEGVVKFERKGPRQVRTVSVVSAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS2_ECOL5
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: KRA92_HUMAN
Sequence: MTHCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPACCVSSCCQPCCRPTCCQNTCCRTTCCQPTCVTSCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCGQSSSCAPVYCRRTCYYPTTVCLPGCLNQSCGSNCCQPCCRPACCETTCCRTTCFQPTCVSSCCQPSCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 9-2, Keratin-associated protein 9.2, Ultrahigh sulfur keratin-associated protein 9.2.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 9 family.
Protein: HUTG_STRGC
Sequence: MLEDYYQLDNSYYQRGVEDNLYAAKWGMVIEFLNLNDPNLKPVEGVNFALIGFKSDKGVYINHGRVGAVEGPQSIRTQLAKLPWHLGRNVHVFDVGDIDGPNRSLEQLQSSLAKAVKRLRELNLRPIVLGGGHETAYGNYLGLKSSLKPEQELAVINMDAHFDLRPYDQTGPNSGTGFRQMFDETLAQKQVFNYLILGIQEHNNNLFLFDFVAKSKAIQFLTGLDIYQMGHKEVCKVVDAFLADKEQVYLTIDIDCFAAGAAPGVSAIQSLGVDPNLAVLVFQHIAASGKLIGFDVVEVSPPHDIDNHTANLAASFIFYLTQVWAQIHD
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GDAP2_MACFA
Sequence: MDPLGAPSQFVDVDALPSWGDSCRDELNSSDTTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEATYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGPYYTSYPPSPDL
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the GDAP2 family.
Protein: UBP1B_ARATH
Sequence: MQRLKQQQQQQQVMMQQALMQQQSLYHPGLLAPPQIEPIPSGNLPPGFDPSTCRSVYVGNIHIQVTEPLLQEVFAGTGPVESCKLIRKEKSSYGFVHYFDRRSAGLAILSLNGRHLFGQPIKVNWAYASGQREDTSSHFNIFVGDLSPEVTDAMLFTCFSVYPTCSDARVMWDQKTGRSRGFGFVSFRNQQDAQTAIDEITGKWLGSRQIRCNWATKGATSGEDKQSSDSKSVVELTSGVSEDGKDTTNGEAPENNAQYTTVYVGNLAPEVSQVDLHRHFHSLGAGVIEEVRVQRDKGFGFVRYSTHVEAALAIQMGNTHSYLSGRQMKCSWGSKPTPAGTASNPLPPPAPAPIPGFSASDLLAYERQLAMSKMAGMNPMMHHPQGQHAFKQAAMGATGSNQAIYDGGYQNAQQLMYYQ
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as a component of the pre-mRNA processing machinery.  Functions to facilitate the nuclear maturation of plant pre-mRNAs (By similarity).
What are the official names of this protein?
Oligouridylate-binding protein 1B, AtUBP1b, Polyuridylate-binding protein UBP1B, Poly(U)-binding protein UBP1B.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_UREPA
Sequence: MERSRRKVLEGLVVSDKMQKTVVVSVETKSKHPIYRKLVISHKKYHAHNDNDDAKVGDLVEITETRPLSATKNWRVSKILERAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ASD_ARCFU
Sequence: MIERSGYGIIAASLLLSAVAYLLHPLISALFVGFALFTAYFFRDPERKIGEGVVSPADGRIDYLEGRRLEIFMSPFDCHINRAPWGGKVLSVKFIEGSTPPAFIRKSGVRTNEILIETEHGVFRVLQMAGIFARRIVSYVSEGDVVKKGQKIGMIRFGSRVVLEVPEGFRFVRGVGEKVKAGETVALRDESFQGS
What is the function of this protein?
Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
What are the official names of this protein?
Putative archaetidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHS3_SORBI
Sequence: MAAATVTVEEVRKAQRATGPATVLAIGTATPANCVHQADYPDYYFRITKSEHMTDLKEKFKRMCDKSQIRKRYMHLTEEYLAENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSMVGQALFGDGAAAVIVGADPDERVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERSLEEAFKPLGITDYNSIFWVAHPGGPAILDQVEAKVGLEKERLRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGQATTGEGFDWGVLFGFGPGLTVETVVLHSVPITTGAAITA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 3, Naringenin-chalcone synthase 3.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PIMT_SALSV
Sequence: MVSGRVQALLEQLRAQGIRDELVLNALAAVPREKFIDEAFEHKAWENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMAQLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEAD2_MOUSE
Sequence: MGDPRTGAPLDDGGGWTGSEEGSEEGTGGSEGVGGDGSPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPSGPQATELFQFWSGSSGPPWNVPDVKPFSQAPFSVSLTPPASDLPGYEPPPALSPLPPPAPSPPAWQARALGTARLQLIEFSAFVEPPDAVDSFQRHLFVHISQQCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSAEEAGSSGGGGGFYGVSSQYESRELMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQYHIYRLVRD
What is the function of this protein?
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction (By similarity).  Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3').  May be involved in the gene regulation of neural development.  Binds to the M-CAT motif.
What are the official names of this protein?
Transcriptional enhancer factor TEF-4, ETEF-1, Embryonic TEA domain-containing factor, ETF, TEA domain family member 2, TEAD-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTD_HISS2
Sequence: MIALIQRVSHAKVEVGQNIVGQIGQGLLVLLGVEKDDDRSKADKLAEKVLNYRIFTDENGKMNLNLQQIGGEILIVSQFTLAADTQKGLRPSFSKGADPELAEKLYQYFSQKCAEKVRVANGQFAADMQVSLTNDGPVTFWLNV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y782_STRMU
Sequence: MTVNVYDLANELERGIRALPEYQALVQAKAKIDEDEEAKKLWTEFTEFQMKIQGLIQTGQAPTPEVQTEMQSFNQKIEANPLLKEYATAQQALGVYVNDIERIIFSPLQDIAK
What are the official names of this protein?
UPF0342 protein SMU_782.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: Y612_RHIME
Sequence: MKADRNLRLCDVVLDETIGRSTPDVEHERAVAIFDLLEENLFEPVGHPGGPYRLNLSLVDAKLVFRISTDGGTEVATHILSLTPFRRIVKDYFMICESYYQAIRSATPSQIEAIDMGRRGIHNEGSQTLMDRLSGKIRLDFDTARRLFTLVCVLYWRG
What are the official names of this protein?
UPF0262 protein R00612.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: TYRA_STAAB
Sequence: MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKSIGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIDMPTKPGVIVSDTGSTKAMIQQHECSLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLKELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGFRDITRIASSNVQMWKDITLSNKTYILEMIGQLKSQFQDLEKLIESNDSEKLSSFFAEAKSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYILSLHNISISNLRILEVREDIYGALKISFKNPTDRERGMQALSDFDCYIQ
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: SYFA_FERNB
Sequence: MSYREEAKSILEQAKNEITNAENSKVLNDLRVKYLGKSGIVTSLMKQLKDLPNEEKPIFGKVVNELKESIEKLLDEQKEKITEYEKEEAYKKLWVDPTMPGAIRSVGHLHILTKVRNELEDIFISMGFSVVEGPEVETPWFNFDALNTPEWHPARDEHDSFYIDNEHLLRTHTSPVQIRTMLSRKPPLAIVSPGRVYRRDYDATHLPMFTQMEGLYVDHDVTVKHLKYFLEEFARRLLGENTKIRLRPSFFPFTEPSFEVDIYFNNRWFEVLGSGMVHPNVFKNVGYDPEEWRGLAFGFGIERIAMVKYGIKDIRDLVRNDVRFLENW
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CST9_MOUSE
Sequence: MSCPLRKKALPLTMLLLLLSFHVLITPVSKANKETNRSVHFIPTVEFAVNTFNQESQDEYAYRMEHIMSSWREKVNFPTVYSMRLQLRRTICKKFEESLDICPFQESHGLNNTFTCLFTVGTYPWITKFKLFRSVCS
What is the function of this protein?
May be involved in testis development (PubMed:9826679).  May play a role in hematopoietic differentiation or inflammation (By similarity).  Has immunomodulatory and antimicrobial functions against Francisella tularensis, a Gram-negative bacteria (PubMed:23922243).
What are the official names of this protein?
Cystatin-9, Testatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVA_PSEPK
Sequence: MIGRLRGTLAEKQPPHLIIDVNGVGYELEVPMTTLYRLPKVGETVTVHTHLVVREDAHLLYGFAEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSALVRVPGVGKKTAERLLVELKDRFKAWETSPAMFTLVSDGPLPVASESSAEADAVSALVSLGYKPQEASKAIAAIKDKAGLSSEELIRRSLKGMISK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: VATF2_DROME
Sequence: MSTPTHNLPRTRVSAFCWVALERSTRIERPTSWSWKELSHYSLIVFHCIPDTTPKQIEECFKKFLRRPDIVIILINQVYADMIRPTVDAHNLAVPTVLEIPSKQHPYDSSRDSILKRAQRVITPPERHY
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit F 2, V-ATPase subunit F 2, Vacuolar H+ ATPase subunit 14-2, Vacuolar proton pump subunit F 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: THRC_SERMA
Sequence: MKLYNLKDHNEQVSFAQAIKQGLGKQQGLFFPLDLPEFELTEIDHLLEQDFVTRSSRILSAFIGEEVPETALKKRVQAAFEFPAPVAKVTDDVSCLELFHGPTLAFKDFGGRFMAQMLAEVAGEQPVTILTATSGDTGAAVAHAFYGLKNVRVVILYPQGKISPLQEKLFCTLGGNIHTVAIDGDFDACQALVKQAFDDQELKDALHLNSANSINISRLLAQICYYFEAVAQLPQEARNQLVISVPSGNFGDLTAGLLAKSLGLPVKRFIAATNANDTVPRFLTSGQWQPHATVATLSNAMDVSQPNNWPRVEELFRRKVWQLKELGHAAVSDETTKDTMRELAELGYISEPHAAIAYRALRDQLQEGEFGLFLGTAHPAKFKESVEAILGQELPLPKALALRAELPLLSHTLPASFGELRKFLMGLPA
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: METAS_ECO24
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLGPEVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.