PharMolix/UniProtQA huggingface dataset:
Protein: VATG2_PANTR
Sequence: MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRHQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
What are the official names of this protein?
V-type proton ATPase subunit G 2, V-ATPase subunit G 2, Vacuolar proton pump subunit G 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
What are the subcellular locations of this protein?
Melanosome. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Note=Highly enriched in late-stage melanosomes.
Protein: NUDB_ECOLI
Sequence: MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA
What is the function of this protein?
Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate.  Required for efficient folate biosynthesis.  Can also hydrolyze nucleoside triphosphates with a preference for dATP.
What are the official names of this protein?
Dihydroneopterin triphosphate diphosphatase, Dihydroneopterin triphosphate pyrophosphatase, dATP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: KYNU_SCLS1
Sequence: MGSIAKEEQPSKVEKPTFSSKANTLEYAQSLDANDHMRRFRDQFIIPSKANIKATKLEKPGLSDESSIYFCGNSLGLQPKCVKEYLQAHLDTWSSIGVHGHFRDLEDSPLTQWQLLAEHASKQCAPIVGAKASEVAMMGTLTTNLHLLMASFYTPTPEKNKIIMEWKAFPSDHYAIESQIRGHGYNPQEAMVMIGPEEGSYEISTEKILRTIDEHASTTALVLLPGIQYYTGQLFDVKTITAYAQSKGLIVGWDLAHAAGNVPLQLHDWNVDFAVWCTYKYMNAGPGSIAGAFIHERHGEVDYSEGEEKPKYRHRLMGWYGGDQSCRFLMNNKFRPSPGASGYQVSNPSVVDLTSLCAALSIFNQTSMEEISQKTLHLTAYLEHLLLTSNPSNTNPAFRIITPSDPSARGTQLSVLLKPGRLETLSDMLEEAGIVADKRKPDVIRVAPVPLYNTYEDVWRFVQIFNAALEKCEEA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, Biosynthesis of nicotinic acid protein 5, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3436_YERE8
Sequence: MSAVTPLLDGLALRLYIQPKASRDQIVGLHGDELKVAITAPPVDGQANAHLIKFIAKQFRVAKSQVIIEKGELGRHKQIKIVNPQQIPPEVATLLE
What are the official names of this protein?
UPF0235 protein YE3436.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: YHAM_ECOBW
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: TOLB_RUEST
Sequence: MRNAIATVLLGLAMLLPVGAVQAQDGPLRIEITDGVIEPLPFAVPDFIADTPAAAQYATDIARVIAQDLVGSGLFREIPKVAYISPYTDFDAEVNFTDWKAINAQALIAGAVSLSGDRITVRFRGYDVFAGQELGAGLQLSGTTDGWRRIAHKVADTIYSRLTGEGGYFDSRVVFVSETGPKNDRKKRLAIMDYDGANVQYLTNSDAIVLAPRFSPTGDRVLYTSYESGFPQIHVLDVGRVQRRVLSAGNGSMSFAPRFAPNGQTIVYSQSQGGNTDLFSMDINSGNPQRLTSAPSIETAPSFSPDGSQIVFESDRSGTSQLYVMSASGGEAKRISFGQGRYGTPVWSPRGDYIAFTKQNAGRFHIGVMRTDGSEERLLTASFLDEGPTWSPNGRVIMFTRETQGASGQARLYSVDISGRNLKPVKTPDGASDPSWSPLQN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KT3K_THET8
Sequence: MDPLALLRKAGLEAEGPALPLHGGDISRVWRVGRFVVKTAQDPPPGLFRAEARGLQALAERGVRVPRVHWVGEEGLVLAYLEPGPEDWEGLARTLAALHRRREGSYLAEPGFLGTFPLPGREGGEWTAFFYERCVLPLLEATWDRLQGLGPKVEALYQRPLPAEGPAPLHGDLWHGNVYFAREGPALLDPSFFVGERGVDLAMMRLFGGFPRRFWEVYGELYPVPEEVERALPRYQVYYLLAHVHFFGQGYLGALWRAISAS
What is the function of this protein?
Ketoamine kinase that phosphorylates ketoamines, such as erythruloselysine and ribuloselysine, on the third carbon of the sugar moiety to generate ketoamine 3-phosphate (PubMed:17681011).  Has higher activity on free lysine (erythruloselysine and ribuloselysine), than on ribuloselysine and erythruloselysine residues on glycated proteins (PubMed:17681011).
What are the official names of this protein?
Probable ketoamine kinase TTHA1179.
What is the protein family that this protein belongs to?
Belongs to the fructosamine kinase family.
Protein: METK_COLP3
Sequence: MSRHFFTSESVSEGHPDKIADQISDAVLDAIIAKDKHARVACETMVKTGVAIISGEVSTNAWVDLEKLTRNVISDIGYTSSDVGFDGATCGIMNLIGQQSPEIAQGVDRSNPEEQGAGDQGLMFGYATNETPTLMPAPLYYSHRLVERQAEARKSGVLPWLRPDAKSQVTFIYEDNKPVAIDTVVLSTQHNPDIKQEDLVSAVMENIINHVLPAELLTEDTKYHINPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADRCEIQISYAIGVAEPTSISIDTFGTGSISEERLVEIVREHFDLRPYGITKMLDLLHPMYQQTAAYGHFGREPFEMTVGDDTFTAFSWEKTDKADDLRKAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BURO0
Sequence: MPRRREVPKREVLPDPKFGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LOLB_RALPJ
Sequence: MAMRFAHALGALMLGAGCALFSGCASLRPANDLFAGTQDADTNITRYQGRFSARYTQNNAEQSAVGSFLWRERGPDVQLELMSPLGQTLAIVSQSNQGATLELPNQPPRRAPEVDTLMQDALGFSLPVSGLRDWLRARPAPGTPARVARDAQSRPETIEQNGWTVHYVAWTDDGNNTDGAKVGIRRLDLDRPQGTNGPLSVRLVLDQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: LA_RAT
Sequence: MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVDTPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHGEIKWIDFVRGAKEGIILFKEKAKDALEKARSANNGNLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHRRGPVKRGIDGRDREEPASKHKKRENGARDK
What is the function of this protein?
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
What are the official names of this protein?
Lupus La protein homolog, La autoantigen homolog, La ribonucleoprotein.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUI1_SCHPO
Sequence: MSAIQNFNTVDPFADTGDDDAQPLNNIHIRIQQRNGRKTLTTVQGLPREFDQKRILRALKKDFACNGTIVKDDDLGEVIQLQGDQRIKVMEFLTQQLGLQKKNIKIHGF
What is the function of this protein?
Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.
What are the official names of this protein?
Protein translation factor sui1.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: METK_GRABC
Sequence: MRDKGEYLFTSESVSEGHPDKVADRISDTVLDAFLKADPYARVACETLVTTNRVVLAGETRGPASVTPELLENLTREAIKDIGYDQEGFSWKNADVAIHLHAQSADIAVGVDSTGNKDEGAGDQGIMFGYACRETPALMPAPIYYSHEILRRLTELRKSGSTEGKLLEPDAKSQVTLRYVDGRPVGATSVVVSTQHGEAASQDELRRIVTGVIGQVLPDGWMPPEQEIYVNPTGKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYVARYLAKNVVAAELADRVTLQISYAIGVSHPLSVYVDLHGTGHDVDEVKLEKTLRELVNLSPRGIREHLRLNRPIYVPTSAYGHFGRTPDMALDNFTWEQTDIAAALRSAFNR
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_STRPS
Sequence: MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYY_STRPQ
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIESQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRIQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2S1_HUMAN
Sequence: MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of retinoids and eicosanoids (PubMed:12711469, PubMed:21068195).  In epidermis, may contribute to the oxidative metabolism of all-trans-retinoic acid.  For this activity, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:12711469).  Additionally, displays peroxidase and isomerase activities toward various oxygenated eicosanoids such as prostaglandin H2 (PGH2) and hydroperoxyeicosatetraenoates (HPETEs) (PubMed:21068195).  Independently of cytochrome P450 reductase, NADPH, and O2, catalyzes the breakdown of PGH2 to hydroxyheptadecatrienoic acid (HHT) and malondialdehyde (MDA), which is known to act as a mediator of DNA damage (PubMed:21068195).
What are the official names of this protein?
Cytochrome P450 2S1, CYPIIS1, Hydroperoxy icosatetraenoate dehydratase, Thromboxane-A synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: LDH3_BACC1
Sequence: MKRNTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEKKDQFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDYRVIAVSAILDGEYGEYDLCTGVPAIITRDGIKEIVELNLTEDEESRFAKSNDILRDYMKTIGY
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 3, L-LDH 3.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_LACLA
Sequence: MQENRPVIALDFPEFSDVKDFLEKFDPSEQLYIKLGMELFYTAGPQVVYYVKSLGHSVFLDLKLHDIPNTVESSMHVLARLGVDMVNVHAAGGVEMMVAAKRGLEAGTPVGRQRPKLIAVTQLTSTSEEIMQNDQKIMTSLEESVINYAQKTAQAGLDGVVCSAHEVEKIKAATSKEFICLTPGIRPEGASKGDQKRVMTPKEARTIGSDYIVVGRPITQAKDPVASYHAIKAEWNR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DER_ECOHS
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GLPG_KLEP3
Sequence: MLMITSFANPRVAQAFVDYMATQGIILTIQQHAQSDVWLADESQAGRVRAELARFLENPADPRYLAASWQSGQTNSGLRYQRFPFFATLRHNAGPFTWAILLICIAVFILQNLLGDQPVMIWLAWPYDPSLQFEAWRYFSHAFMHFSLMHILFNLLWWWYLGGAVEKRIGSGKLVVITVISALLSGFVQHQFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLILFSLVWLIAGWFDVFGMAIANGAHVAGLATGLAMAFVDTLHGRKRA
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSF1_CAEBR
Sequence: MSSNDQQRGGVADKALQLVMEMKRNPDVLPPYNADLVRQCQKKIDELFHKNAAVVERMRNGLEHDPSLLQPRLAAMCHIRRCMMAYVNERKNRIRSFRWRYGGALPASVRNALCEAEIQFFNEYSSTLARFQSNLGEAGVNLLLHTAPPKTLFVQVRTLEDYGEFETSDGTQVQLTKDSLHSLPRQDCEMLIRQGVLELVH
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
Probable DNA replication complex GINS protein PSF1, GINS complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TGT_DEHMC
Sequence: MDKSFILNKTSSRSLARRGQLFTAHGKVETPVFCPVGSQAAVKTLTPEDLKSVNINMILSNTYHLYLRPGIPIIKEMGGLHKFMNWDEVILTDSGGYQIFSLANLRKLDEGGVSFRSHIDGSTRYITPEDAVSFQQDLGSDIAMVLDECPHSEASENEVLAAMERTHQWAKRCLAAHTLKIQHLFAIVQGGLSPELRRQSAEYLASLDFPGYALGGLSLGEPKDITFETVRHTLRFLPENKPRYLMGVGAPEDLLEGVSCGVDIFDCVLPTRVARNGAFFSRLGRLNIRNAAFATQKGPIDPECNCYTCRNYSAAYLHHLFRCEEILAYRLATIHNIAFLSNLMQEIRTSIEKDCFEEFKADFLSRYQPTNEAIRIEQKQKWLFGRNGEPPS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: SYT_PHYAS
Sequence: MIKINLLNHQSHSFPSKTTPLEIWKNWLKKTLKKPVAALFNQKFIELDYPLTQDGDLEILAESNPKSLFVLNHSTAHLMAQAIQRLYPNALFTIGPAIKEGFYYDIDFQNHSISEKDLPTIEKKMHEVALENHSMIMKKVTHDEAKRLFSYNPYKLILLEKHKEEDITVCHQGEFIDLCRGGHIPKLSLIKHFKLLKISGSYFQGDAKNKSLTRIYGTSFFKKEDLGNYLKLLEERKERDHKRLNKKLDLFMFSQEVGLGLPFWLPKGATLRRIVERYIVDKELSHQYHHVYTPIMANVELYRTSGHLEHYSQNMFPVMQLENKEKIVLRPMNCPHHMMIYKKSPRSYKELPLRIAELGMMHRFEKSGAVSGLQRVREMNLNDAHNFVRPDQIEEEIKKIINLILEVYRDFKITKYEFRLSYRDPQDKEKYFPDDNMWQHAENILKKTIQELNLPFREAIGDAAFYGPKLDVQVLTALGNEETLSTIQLDFLLPQKFDLTFIDANNKHCRPVVIHRAIVSTLERFLSHLIEENKGVFPLWLAPVQILLIPVSSSVNLKYTQEIKELLLSQGLRAEINSKEATLGYKIREAQELKIPYQIVVGDNEIAKNLITFRKYGQKNQTTTNIETFISSLNQEIMEKR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_XANP2
Sequence: MRILILGSGVVGTASAYYLAKAGHEVTVLDRQRAAGMETSFANAGQVSPGYSAPWAGPGIPVKAIKWLLMHHRPLVVWPSLDPKLYLWLAKMLANCTEEAYRRNKARMVALAEYSRDALDALRSETGIAYDERMLGTLQLFRTRKQLDHVHSDTEVLDAHNVRYELLDPSGCIRAEPALARVRDKFVGGLRLPGDETGDAHIFTRNLADICARQGVTFRYGVTVEGLRHEAGRITGVALAGGEIATADIYVAAMGSYTPALLAPLGIRLPVYPVKGYSLTLPITDPDAAPRSTVMDETYKVAITRLGERIRVGGTAELAGFDLSLREPRRATLAHSVGDLFPAGGDISKATFWTGLRPMTPDGTPIIGPTKLDNLFTNTGHGTLGWTMACGSGRVLADLIGGRAPDIDTADLSVARYAEAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: CCMB_ECO57
Sequence: MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVLLSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein B, Cytochrome c-type biogenesis protein CcmB.
What is the protein family that this protein belongs to?
Belongs to the CcmB/CycW/HelB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_CARIN
Sequence: MTTNLRKTHPLLKMINNSFIDLPTPSNISIWWNFGSLLGACLILQTITGLFLAMHYSSDISLAFSSVTHITRNVQYGWLIRNMHANGASLFFMCIYLHIGRGIYYGSYLYKETWNIGIMLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAMPYIGNTLVQWVWGGFSIDNATLTRFFTLHFLLPFSIMGLTIVHLMFLHETGSNNPTGLNSNIDKIPFHPYFSYKDALGLILMLTTLLTLTLFFPNLLGDPENFTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILFLLPTLHTSKQRSMMFRPISQMLFWSLVADLLILTWIGAQPVEDPFIMIGQLASIMYFTILLILLPITSIIENKMLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURB_BURM1
Sequence: MPMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLGGGSNVVFTRDFDGLVLLDEIAGRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRSERFDAARCAFGYRDSFFKRDGRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPDPRELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGADVLALARAIQHDVRTQFGVELEPEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_XYLFA
Sequence: MCASFSPTLDSRSRQLLRTLISCYIQNGEPVGSKTLAQQAGLDISPATIRNILADLEELGLLNSPHTSAGRVPTAHGYRMFVDSLVQMQPPSEDDIRRLRVEMAGGGTQALLGNASEILSAMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFADNEVQNRVIEPRRVYEPGELERVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTGQTRLMALQDLSDMDRLRELFEIFASKREILQLLERTINAPGVRIFIGEETGMVSMEDISLVTAPYAAHGQVLGVLGVIGPKRMAYDRVIPLVQVVAQVLGTALEPPTMP
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.