PharMolix/UniProtQA huggingface dataset:
Protein: LN28A_XENLA
Sequence: MGSVSNQEITEGLPKSLDGTADIHKSDKSVIFQGSGVCKWFNVRMGFGFLTMTKKEGTDLETPLDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESTQVTGPGGAPCIGSERRPKVKGQQKRRQRGDRCYNCGGLDHHAKECKLPPQPKKCHFCQNPNHMVAQCPEKAMQAANLEDQPITEEQELIPEIME
What is the function of this protein?
RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism.  Seems to recognize a common structural G-quartet (G4) feature in its miRNA and mRNA targets (By similarity).  'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis.  Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization.  Suppressor of microRNA (miRNA) biogenesis, including that of let-7.  Binds specific target miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in their terminal loop, and recruits uridylyltransferase.  This results in the terminal uridylation of target pre-miRNAs.  Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation (By similarity).  Localized to the periendoplasmic reticulum area, binds to a large number of spliced mRNAs and inhibits the translation of mRNAs destined for the ER, reducing the synthesis of transmembrane proteins, ER or Golgi lumen proteins, and secretory proteins.  Binds to and enhances the translation of mRNAs for several metabolic enzymes, increasing glycolysis and oxidative phosphorylation.  Which, with the let-7 repression may enhance tissue repair in adult tissue (By similarity).
What are the official names of this protein?
Protein lin-28 homolog A, Lin-28A.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Cytoplasm. Rough endoplasmic reticulum. Cytoplasm, P-body. Cytoplasm, Stress granule. Nucleus, nucleolus. Note=Predominantly cytoplasmic. In the cytoplasm, localizes to peri-endoplasmic reticulum regions and may be bound to the cytosolic surface of rough endoplasmic reticulum (ER) on which ER-associated mRNAs are translated. Shuttle from the nucleus to the cytoplasm requires RNA-binding.
Protein: GPT_CRILO
Sequence: MWAFPELPLPLLVNLFGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVICGAVFLIILFCFIPFPFLNCFVEEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNLPWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDYRDDHVFSLYFMIPFFFTTLGLLYHNWYPSQVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFIPQVFNFLYSLPQLLHAIPCPRHRIPRLNPKTGKLEMSYSKFKTKNLSFLGTFILKVAERLQLVTVHRGESEDGAFTECNNMTLINLLLKIFGPIHERNLTLLLLLLQILSSAVTFSIRYQLVRLFYDV
What is the function of this protein?
Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ISPG_RHOPT
Sequence: MNKLENPLRDDVAGPAPRHQTTQVMVGDVAVGGGAPIVVQSMTNTDTADVEGTIKQIAALARAGSEMVRITVDREEAAAAVPHIRDGIRKLGLTTPIIGDFHYIGHKLLAEYPACAEALDKYRINPGNVGFKNKRDTQFADIVEIAIKNNKAVRIGANWGSLDQELLTKLMDENAASANPRDVRAVTREAMVQSALLSAARAEEIGLPKNKMILSAKVSAVQDLIAVYQDLASRSDYAIHLGLTEAGMGSKGIVASSAALGILLQQGIGDTIRISLTPEPGGDRTREVQVGQELLQTMGFRTFVPLVAACPGCGRTTSTTFQELARSIQDFIRDEMPEWRSRYPGVENLNVAVMGCIVNGPGESKHANIGISLPGTGETPAAPVFVDGEKFRTLRGENIAADFKALVIDYIEQRYGATPKPGAAQMVPAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: IF2_CAUVC
Sequence: MSDENENGRPGGRTPMTLKPRQGSVSAGVVKQSFSHGRTKTVVVETKRTRTHAPASGNLAAPSSAERRHGEAPAPRPAPPQGGGGGSAGGLSQEELRARQRVVDAAREAQARQVAEQAAAEARARAAQEAAQREAAAKAAAERAAAAPPPVAQAPAAPAPAAPVTPPPAAPQAPRPVAQAPVAPSAPRQDAPRQDTRAAAPGQTRTYEPSRDRRDDRPSTTTYRPAPQGDRPFNQRAPRPDANANFGQRAPRPEGDRPRGPRPDGDRPQGDRGGYRGDRPQGDRPQGDRPQQTVRYSALAPRPAPGARGPGGPPRGPRPGVPAAAPATPEIQRATRSAPRPGGGAMDRRPDEDDDRRKNAAPNKAVSRVKGAPQRREGRLTIQAVAGDGDSADRMRSLASVRRAREREKEKRRGGAVEQARVAREVVIPDVITVQELSNRMAVRGVDIIKFLMRQGVMLKINDVIDNDTAELVATEFGHTVKRVSEADVEEGFIGADDHDEHMDLRPPVVTIMGHVDHGKTSLLDALRSTDVAAGEAGGITQHIGAYQVRLKDGQRVTFLDTPGHAAFSSMRARGANITDIVVLVVAGDDGVMPQTIEAIKHAKAAEVPIIVAVNKMDKPGSDPTRVVNELLQHEIVVESLGGDTQLIEVSAKARTGLDNLLEAILLQAEVLDLKANPDRSADGVVIEAKLDKGRGAVSTVLVNRGTLKRGDIVVAGSQWGKVRALLNERNEQLQEAGPATPVEILGLDGVPSPGDAFAVVENEARARELTEYRIRLKREKSMAPVGAGASMADMMAKLQDKKLKELPLVIKADVQGSAEAIIGSLDKMATDEVRARIILSGAGAISESDVMLAKGAGAPVIGFNVRASAQARALAEREGVEIRYYAIIYDLLDDIKGVLSGMLAPIQRETFLGNAEVLQAFDISKIGKVAGCKVTEGVVRKGAKVRIIRQDIVVLELGTLQTLKRFKDEVNEVPVGQECGMMFAGFQDIKVGDTIECFTVEEIKRQLD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPL_STRRN
Sequence: MQTKVLCQRDIKRILSVVGRDVMMDRLISEVHAGFARLGRGETDEPPPRTGFARGGDVPGVIEFMPHRASGIGVTMKTVSYSPQNFERFNLPTIVGTVSRLDDDSGSMVALADAATITAMRTGAVAAVATRLLARPGSTTLALIGAGAQAVTQAHALSRVLPLERILISDIKAEHAESFAGRVAFLELPVEVTDAATAMATADVLCTVTSVPVGGGPVVPAEPRQAHLHVNGIGADEQGKTELPKALLDDAFICVDHPGQARAEGEFQQLPDRELGPSLADLCAAPEIAAPHPERLSVFDSTGSAFADHIALDVLLGFADELGLGHKMSIESTPEDVLDPYSL
What is the function of this protein?
Converts L-lysine to L-pipecolate, which is incorporated into multiple secondary metabolite products, including rapamycin, tobulysin, virginiamycin and pristinamycin.
What are the official names of this protein?
L-lysine cyclodeaminase, Rapamycin biosynthesis protein L.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: RPIA_ECO45
Sequence: MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RS16_BORBR
Sequence: MLVIRLARGGSKKRPFYNLVATDSRNRRDGRFVERVGFYNPVAAEGTENLRIALDRVQYWTGNGALLSPAVERLVKEYSAKVSAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CLPP_PELHO
Sequence: MPVGVPKVPFLNPNPDPEPDSVEEELDSMEEKATWVDLYNRLYRQRWLFLGKDLEEEVANNIVGLMIHLNIEDPFWTQTLYINCLGGLIIPGLALYDTIGFVEPDVKTICLGIAASMASVVLVGGTVTERCAFPNARVMIHQPRAKEFDDRFSDLNLEGHLFLQLRNCVTQIYIHRTNKPAWVIIADLERDTFMSATEARTYGIIDGVYAFEEEYEEWS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CHIS_NOCSP
Sequence: MRLKHPTARLALAALLVAVPRSVAAAGTVHAAPAPAGATRLAAVGLDDPHKKDIAMQLVSSAENSSLDWKSQYKYIEDIKDGRGYTAGIIGFCSGTGDMLDLVADYTDLKPGNILAKYLPALRKVNGTESHAGLASAFEKDWATAAKDSVFQQAQNDERDRSYFNPAVNQAKASLRALGQFAYYDAIVMHGPGDSSDSFGGIRKAAMKKAKTPAQGRDEATYLKAFLAARKTVMLKEEAHSDTSRVDTEQTVFLNAKNFDLNPPLKWKVYGDSYAINS
What is the function of this protein?
Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
What are the official names of this protein?
Chitosanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 46 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y147_MYCGE
Sequence: MLLLRALFLELKTNKNCKALLLLLIPLLVGLTLIIYGIVLFSTEGVIDHGDHNHLRARFQLTLEEIIVFVVGSIILFFTLASFCVSCFMLMRSPKQKQLEVDHANKTNLKPKAIVNCDLFQLGDYCVFTFKKLSFKQRFKQDFFARSKFSFRSELYRLCLVGVLIALNLALSLIEIPGIVLPWGSSIQFRFFNTAILFIAVRLVGLLSTSLVALITPWLHLLIHPIHTPISSLFYMVNDFLVLWIFYFFFFHLFKAEVIQTTTVVDNKPFSQLVNTKKTKWTKFFSLLVISFLCGFIEGLGFYFGYFLILGNVSSLGLKIYYDGLQQRDLINSSNVLFFLMTTTAIFSIKYIFEMLFFFSVEKNVVNIANHFGLY
What are the official names of this protein?
Uncharacterized protein MG147.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_CAMHC
Sequence: MKIVFMGTPEYATAILRALFENNFKISAVFTQPDKPVGRKQILTPPDVKKFLLESHADTPIFQPSNIKTPEIAKKICEFSPDFIVVAAYGQILPLEILEICPCINLHASILPKFRGASPIQSAILEGEKISGVTAMKMGAGLDDGDILGFSFCGIQKLDESEVFHKFGNVAAKLCIKILQNFDDIAPLKQKNVLSSKCKKIKKTDGLVKFSDSADEISAKFSAFKTWPGIFLENGTKLLEIRKFSDEKKEFGKISHITKDGFTLAVKDGEIEILKLQEPSKKAILARDFINGKRLKIGDRIS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CT15_CONCL
Sequence: MRCLPVFIILLLLASTAAVDVAGSKLKRRLERKPYQGSQAYVKKTAFGLRLCCKRHHGCHPCGRT
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal1.5, Conotoxin Cal1.1b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DBH_THEMA
Sequence: MTKKELIDRVAKKAGAKKKDVKLILDTILETITEALAKGEKVQIVGFGSFEVRKAAARKGVNPQTRKPITIPERKVPKFKPGKALKEKVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: A1I2_LOXSP
Sequence: WIMGHMVNAIGQIDEFVNLGANSIETDVSFDDSANPQYTYHGVPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLVLVVFDLKTGSLYDNQANEAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLTQEGHPELLDKVGYDFSGNDAIGDVANAYKKAGVTGHVWQSDGITNCLLRGLTRVREAVANRDSGKGYINKVYYWTVDKRASTRDALDAGVDGVMTNYPDVITDVMNEAAYKNKFRLATYEDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspaSicTox-alphaIA2ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHS_CHRVO
Sequence: MNLLELSCTPQHGQSPLADNTVKQLLSTLPDWEIVGIELRKTYRFANYHETMAFVNALAWIANQEDHHPDMSVHYNRAVVNFSTHDAGGLTLNDFICAAKTEALFRRP
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: WNT5_DROME
Sequence: MSCYRKRHFLLWLLRAVCMLHLTARGAYATVGLQGVPTWIYLGLKSPFIEFGNQVEQLANSSIPLNMTKDEQANMHQEGLRKLGTFIKPVDLRDSETGFVKADLTKRLVFDRPNNITSRPIHPIQEEMDQKQIILLDEDTDENGLPASLTDEDRKFIVPMALKNISPDPRWAATTPSPSALQPNAKAISTIVPSPLAQVEGDPTSNIDDLKKHILFLHNMTKTNSNFESKFVKFPSLQKDKAKTSGAGGSPPNPKRPQRPIHQYSAPIAPPTPKVPAPDGGGVGGAAYNPGEQPIGGYYQNEELANNQSLLKPTDTDSHPAAGGSSHGQKNPSEPQVILLNETLSTETSIEADRSPSINQPKAGSPARTTKRPPCLRNPESPKCIRQRRREEQQRQRERDEWFRGQSQYMQPRFEPIIQTINNTKRFAVSIEIPDSFKVSSEGSDGELLSRVERSQPSISSSSSSSSSSSRKIMPDYIKVSMENNTSVTDYFKHDVVMTSADVASDREFLIKNMEEHGGAGSANSHHNDTTPTADAYSETIDLNPNNCYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAPEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGRLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTCK
What is the function of this protein?
Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.  May have a role in limb and CNS development; may be a downstream target of Dll that acts in the specification of these primordia.
What are the official names of this protein?
Protein Wnt-5, dWnt-3, dWnt-5.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HBA_DANRE
Sequence: MSLSDTDKAVVKAIWAKISPKADEIGAEALARMLTVYPQTKTYFSHWADLSPGSGPVKKHGKTIMGAVGEAISKIDDLVGGLAALSELHAFKLRVDPANFKILSHNVIVVIAMLFPADFTPEVHVSVDKFFNNLALALSEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin aa1, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CUTR_STRIS
Sequence: MIEELGKIDRIIQESVPGKQITLAHVIAAPIEAVYECLGVDHEGAIGVVSLTPNETAIIAADIAGKAANIDICFVDRFTGSVMFSGDIQSVETSLEDILEYFKNSLGFSTVPLTKS
What is the function of this protein?
A minor shell protein of the choline degradation-specific bacterial microcompartment (BMC).  Proteins such as this one with circularly permuted BMC domains may play a key role in conferring heterogeneity and flexibility in this BMC.
What are the official names of this protein?
Bacterial microcompartment shell protein CutR, Bacterial microcompartment protein homohexamer, BMC-H, Propanediol utilization protein CutR.
What is the protein family that this protein belongs to?
Belongs to the EutS/PduU family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: MNN23_CANAL
Sequence: MSINFLSIPRNRFKAIGVLSVTCILIYVILHSSIITTDFDVSDYGDKFIPSIIFDDNNDNGENLKDPQPELDNDKGNGETDTTTSNSMTTAHTFWKGIFDTFDKYKMDLGQDPENAVSYVDKLKQKQGPLNKEVLLSKAIVSSELMKHLKEKHSGVVEDLPSVMPGSVYNKGSKGVVIIGGGKFSWLAYLALVQLRNVGSKLPVEIVMPSRADYEKELEFCENTLPEMQASCVVLPDVLGEAVMKNRKFASYQFKALALVVTSFEHILLLDSDNMIVSNPDEIFESKLYHQYGMITWPDYWKRTISPLFYDVAEIEVNENKRVRYNRFPLYNAPNVRSNIYTDQEREEVPFHDLQGSIAELSTESGQLIINKHTHGKTILLALYYNFYGPNLFYKLFSLGEQGEGDKDTFVAAAVVTRQDYYQVKSFIKTFGYADSDDKFQGVSMGQRNPLIDRKHYEDHVLALLEKDSFKSSSIADQIEQMKKFENEDFDQHNSIPLFTVHCNYPKLDPKLYMSRDDLYDEKEKKLKYRLYGNLKYTKEVVKDGETGTEASTDKVQIDFELQQWQHMQDILCLKKIYFTHFIDNDMNELCQFIENQVAWLSKSQN
What is the function of this protein?
Alpha-1,2-mannosyltransferase required for cell wall integrity.  Responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides.  Addition of alpha-1,2-mannose is required for stabilization of the alpha-1,6-mannose backbone and hence regulates mannan fibril length; and is important for both immune recognition and virulence.
What are the official names of this protein?
Alpha-1,2-mannosyltransferase MNN23.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: HTPG_CHLPM
Sequence: MSKKTNAPVQEFEYKAEMKQLLDLIVHSLYTHPEIFLRELVSNAADALSKARFSSLTDGGLMAAAGEDAIHITLDKEKLLFVIEDSGIGMSEDELIANLGTVAKSGTLGFMQSLQEQKKELDGNLIGQFGVGFYSVFMVTENVTVETRSAQEGSEGLRWQSSGQGTYTIEKVEKKERGTRISFTLKEEYKEFAEEYRVEQVIKKYSNFVDFPIYLGEKQLNSVTALWQRPKSELQEGDVHEFYKFISNDFEDPLDYLSVSVEGAVSFKALLFLPQNAPMELLYRQGELENKGPQLYVKKVMIQNECRDLLPEYLRFIAGVVDTEDLSLNVSREVVQSSPVMAKIRQILTTKILGWFEELAVEQPEKFKTFYKAFGPIVKIGLNTDFTNRDKLIELLRFESTKTGEGEFVTLKEYVARMGGEQKEIYYHSGAGRAQLLANPNLEYFQSRGIEVLLLSDPVDVFVIPSIHEYDSKQLKSIEKADIDFSKEKTEGEEPVAENLLVPLLAKFREALGEDIADVVESHRLVSSPVTIVGGKDAMDSQMERMMKMMQQEMPAAKKVLEVNPRHPIIRNLSGMMIANADNPLINSAIRQLYEGALLLEGDLSSTTGFVQRMNELIEAATLSR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_ACIF2
Sequence: MSDLRKTLASLSSAEDFLKFLNIEYDETVVHINRLHILKRFHDYLKREGNTDALDDRALQALYVKLLSQSYQDFVVSDAVSEKVFKVFHQAMGVSHVSLEKVAVSARKGR
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: NBLIK_CUTAK
Sequence: MPFQIPDDLNRDLMPLAWMIGHWEGEGHGNTPDDGEFSFGCQVDFTDNGGDYLHYICQTFTMNPDGTPAAPLRMETGFWRPNVDTRKVDVLMAAPEGWAEVWTGNIDGAKIELVTDAVARTEEALVPYTGGQRLYGQVEGDLLWTFDRATVDAPLQPYMWARLKRS
What are the official names of this protein?
Ferric nitrobindin-like protein.
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: EFTU_PSYCK
Sequence: MAKAKFERLKPHVNVGTIGHVDHGKTTLTAAIATVAAITSGGEAKDYASIDSAPEEKARGITINTSHVEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGPMPQTREHILLSRQVGVPYIVVFMNKCDVVDDEELLELVEMEVRELLSDYDFPGDDTPIIHGSATEALKGSQEKYGQPAVVELLNVLDTYIPEPERDIDKAFLMPIEDVFSISGRGTVVTGRVESGIVRVGDEIEIVGIRDTQKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKREDVQRGQVLAKPGSITPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLQDGTEMVMPGDNVEMGVELIHPIAMDKGLRFAIREGGRTVGAGVVANVLN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_SODGM
Sequence: MMIESSSQDVASLVIALRQQQVIAYPTEAVFGLGCNPDSESAVQALLALKQRPWQKGLILVAAHYAQLKEYIDDDALDDAARSRIFASWPGPVTWVIPVCPTTPSWLTGQHASLAVRVSAFEPVRRLCLAFGKPLVSTSANLTGQPPARSADEVRGQLGAAFLVLDEAVEGRLNPTEIRDALSGELIRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BACC0
Sequence: MPTINQLVRNGRTDKVWKSKSPALNKGFNSLKKKSTDISAPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDKRMQGRSKYGTKKPKAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NOP58_CANAL
Sequence: MAYVLTETAAGYALLKAADKKIHKSSSLVEDLNTAEKVAEQFKIHRFEKFQSAANALEEANAIIEGKVSENLQKLLEDAKSDKKATLIVSEAKLGNAINKLGLNFQVVSDAASLDLQRAIKQFLPELLPGLDDSALKQMSLGLAHSMGRHKLKFSADKVDTMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKMITDSAAYARIILTMGVRSNASETDLSEILPEEVEEQVKAAAEVSMGTEITEDDLNNIKALAEQIVDFAAYREQLSNYLSSRMKAIAPNLTAMVGELVGARLIAHAGSLTSLAKAPASTVQILGAEKALFRALKTKHDTPKYGIIYHASLVGQASGKNKGRIARTLAAKAAVSLRYDCFDEERDESDDFGLENRAKVEGRLSQLEGRDMRTTSKVVREQPKVEITEARAYNADADSTAAAAAAAPTADSDDEESETEEVEEKKSKKDKKKDKKEKKDKKKDKKRKRDDDKEDKESSKKSKKDKKEKKEKKEKKAKKEKK
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CP21A_CANLF
Sequence: MLLLGVLLLTVLAGARLLWGKWKLRGLHLPPLVPGCLHLLQPDLPLHLLGLTQKLGPIYRLRLGLQDVVVLNSKRTIEEAMVRKWVDFAGRPQTPSYKLVSLHHQDLSLGDYSLLWKAHKKLTRSALLLGIRSSMEPLVEQLTQEFCERMRAQAGTPVAIQKEFSLLTCAIICHLTFGDKEDTLVHTFHDCVQDLMRTWEHWSIQMLDIIPFLRFFPNPGLWRLKRALENRDHIVEKQLRQHKESMVAGQWRDMTDYMLQRVGRLRAEEGCGQLLEGHVHMSVVDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDRELGPGASGSRIPYRDPTRLPLLSATVAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGMVVIPNLQGAHLDETVWERPQEFRPDRFLVPGASPRVLAFGCGARVCLGEPLARLELLVVLAQLLRAFTLMPAAGTLPSLRPRARCGVNLSMQPFQVQLQPRGAGVLGRGQHP
What is the function of this protein?
Specifically catalyzes the 21-hydroxylation of steroids.  Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
What are the official names of this protein?
Steroid 21-hydroxylase, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.