PharMolix/UniProtQA huggingface dataset:
Protein: PANB_BACSU
Sequence: MKTKLDFLKMKESEEPIVMLTAYDYPAAKLAEQAGVDMILVGDSLGMVVLGLDSTVGVTVADMIHHTKAVKRGAPNTFIVTDMPFMSYHLSKEDTLKNAAAIVQESGADALKLEGGEGVFESIRALTLGGIPVVSHLGLTPQSVGVLGGYKVQGKDEQSAKKLIEDSIKCEEAGAMMLVLECVPAELTAKIAETLSIPVIGIGAGVKADGQVLVYHDIIGHGVERTPKFVKQYTRIDETIETAISGYVQDVRHRAFPEQKHSFQMNQTVLDGLYGGK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_AGRRK
Sequence: MSTGFFGDIAKVKYEGPDSTNPLAFRHYNKDEVVLGKRMEDHLRFAVAYWHTFTWPGGDPFGGQTFLRPWFNETMEAAKLKADVAFEFFTLLGSPYYCFHDADVRPEGKNFAENTKNLNEIVDYFAQKQADTGVKLLWGTANLFSNRRFMSGAATNPDPDVFAFSAATVKTCMDATHKLGGENYVLWGGREGYETLLNTDLKRELDQMGRFLNLVVEYKHKIGFKGAILIEPKPQEPTKHQYDYDVATVYGFLKKNGLENEVKLNIEQGHAILAGHSFEHELALANALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMSLAYYQVLAGGGFKSGGTNFDSKLRRQSLDPADLLIGHIGGMDCCARGLKAAAKMIEDKALSQPLADRYAGWDSAEGQKLLRGEYSLDQIAQWVEAKDINPQPKSGKQELLENIVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_ACIF2
Sequence: MDEQRSKALSAALSQIDKQFGKGAVMRLGDHNAIKDIEVYSTGSLGLDLALGVGGLPRGRVVEIYGPESSGKTTLTLHAIASCQAAGGTAAFIDAEHALDPGYAHKLGVDLENLLISQPDTGEQALEIADMLVRSGAVDLIVIDSVAALTPKAEIEGDMGDSHVGLQARLMSQALRKLTANISRTNTLVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRIGAIKKSDEVVGNDTRVKVVKNKVAPPFREAEFAIYYGEGISRLSELVDLGVKFDIVEKSGAWYSYQGERIGQGKDNARQYLKEHPELAANIEQRIRAAAAGHPLAFAEEVAEPAAVG
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_COXBU
Sequence: MDKQEKRIRRARRTRAKIKELGAVRLCVHRSLNHIYAQLISPRDSKVLVCASTLEKEVRSQIKHGGNIQAATAIGKLIAQRAKKAGVTKVAFDRSGYKYHGRVRALAEAVREGGIEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RS2_PSYWF
Sequence: MSNSPTNMPMRDLLQAGAHFGHQTRFWNPKMNQYIFGARNKIHIINLEHTVKAFNEALTYVNGLAAKNNKVLFVGTKRAASGVIREQALRAGQPYVDHRWLGGMLTNWKTLRQSINRLKELEKQAEDGTFAKLTKREALERTRAMEKLERSLGGIKNMGGLPDAIFVVDVDHEAIAIKEAKNLGIPVIGIVDTNSNPDNVDYIIPANDDAIRAVTLYVTRMADAIIAGKEYAKTQAGGAAEAPAAEDVQTEEAAAPEADSAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CP6B5_PAPGL
Sequence: MLTIFIVTATLFAILYLYFTRNFNYWKDRNVVGPEPTVFFGNIMESVIRRKHLIMIYKDIYEAFPKEKVVGIYRMTTPCLLLRDLDVIKHVMIKDFDLFNDRGVEFSEEGLGLNIFHADGDRWRVLRQCFTPLFTSGKLKNMLNLMSDRGDKFIKMVEKICDKEPEQQIIPLVRKFTMASITTCAFGMELDEEMIETLDKLDSLIFTTSYGNEIDMMYPGILKKLNSSLFSKMIAPFFDNLTKTIIEQRGGKPTNRKDLMDLILELRQKKAIEPMKKTHDEQVTTLELTDSVIAAQTFIFYAAGYETSASTMSFLLFELAENPDIQEKVIAEVDETLKRHNGEITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAVPGTNVTLKKGQTVVVSGFGIHYDPKYYPDPEKFDPERFSPENVRNRHPCAYIPFGAGQRKCLGMRFGQWQVQVCIIKLLSKFRFEPSTKTMSEF
What is the function of this protein?
Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
What are the official names of this protein?
Cytochrome P450 6B5, CYP6B5v1, CYPVIB5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: KCNE4_MOUSE
Sequence: MLRMEPLNSTYPSAAASSSPLESHVPSNSSGNGNEYFYILVVMSFYGVFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLPIQEEGADDELEETSETPLNDSSEGSSENIHQNS
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Associated with KCNQ1/KVLTQ1 inhibits potassium current (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 4, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CCD1D_DROME
Sequence: MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ
What are the official names of this protein?
Probable cytochrome P450 12d1 distal, mitochondrial, CYPXIID1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: GLNA3_HORVU
Sequence: MALLTDLLNLDLSGSTEKIIAEYIWIGGSGMDLRSKARHLPGPVTHPSKLPKWNYDGSSTGQAPGEDSEVILYPQAILKDPFREGNNILVMCDCYTPRGEPIPTNKRYNAAKILSNPDVAKEEPWYGIEQEYTLLQKDINWPLGWPVGGFPGPQGPYYCGIGADKSFGRDIVDSHYKACLFGGVNISGINGEVMPGQWEFQVGPTVGISAGDQVWVARYILERITEIAGVVVTFDPKPIPGDWNGAGAHTNYSTESMRNDGGFKVIVDAVEKLKLKHKEHIAAYGEGNERRLTGKHETADINTSSWGVANRGASVRVGRETEQNGKGYFEDRRPASNMDPYVVTSMIAQTTILWKP
What are the official names of this protein?
Glutamine synthetase, Cytoplasmic GS3, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_ACIB5
Sequence: MNHPSELKYARTHEWVKIEGDLVITGITDHAQDELGDLVYVETPEVGSQVTAGEQAGVVESVKTASDIHAPVSGTVVEVNTDLEDDPDFVNEDPYGKGWIYKIKPDNIADVEKLLTNAEYEAGL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RN115_MOUSE
Sequence: MAEASAAGADAGSAVAAHRFFCHFCKGEVNPKLPEYICPRCDSGFIEEVTDDSSFLGGGGSRTDNSTATHFAELWDHLDHTMFLQDFRPFLSSNPLDQDNRANERGHQTHTDFWGPSRPPRLPMTRRYRSRGSTRPDRSPAIEGIIQQIFAGFFANSAIPGSPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGEDSTRQTQSSEASASNRFSNDSQLHDRWTF
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes.  Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF115, RING finger protein 115, RING-type E3 ubiquitin transferase RNF115, Rab7-interacting RING finger protein, Rabring 7, Zinc finger protein 364.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
Protein: H2B_ZHASC
Sequence: MPEPAKSAPAAKKGSKKAVSKVQKKDGKKRRKSRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacteria E. coli and the Gram-positive bacteria S. aureus.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Secreted. Chromosome.
Protein: CRTL_DICDI
Sequence: MINRLFSINNIKNGSKFFSSSTTVETKQPLVLLEKHLVNGKYTGIQIVKLNKPKQLNALTFEMGVDYKKVVDTLAEDKDLKCVVLTGEGKAFSAGGDLDFLIERTKDTPENNQRIMERFYRTFLYIRSLPVPIISAINGAAIGAGFCLALATDIRVVSNKAPVGLTFTKLGIHPGMGVTHSITNIVGQDVASYMLLSSDIIKGDEAQRLGLVLKSVESDQVLPTALNLAETISKNSTIAVNSTTKTLRNKYNSDLDKSLTREADAQSQCWASKDIVEGILAIRESRDPKHNYLLFDDQK
What are the official names of this protein?
3-hydroxybutyryl-CoA dehydratase-like protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IXTPA_NOSS1
Sequence: MTKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKATGNWAIADDSGLQVDALNGLPGVYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIASPDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQLTFAEMTPELKKSVSHRGKAFAALLPKMAAMLSSSAE
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: IF2_STAAS
Sequence: MSKQRIYEYAKELNLKSKEIIDELKSMNIEVSNHMQALEDDQIKALDKKFKKEQKNDNKQSTQNNHQKSNNQNQNKGQQKDNKKNQQQNNKGNKGNKKNNRNNKKNNKNNKPQNQPAAPKEIPSKVTYQEGITVGEFADKLNVESSEIIKKLFLLGIVANINQSLNQETIELIADDYGVEVEEEVVINEEDLSIYFEDEKDDPEAIERPAVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTIEAINHAKEAEVPIIVAVNKIDKPTSNPDRVMQELTEYGLIPEDWGGETIFVPLSALSGDGIDDLLEMIGLVAEVQELKANPKNRAVGTVIEAELDKSRGPSASLLVQNGTLNVGDAIVVGNTYGRIRAMVNDLGQRIKMAGPSTPVEITGINDVPQAGDRFVVFSDEKQARRIGESRHEASIVQQRQESKNVSLDNLFEQMKQGEMKDLNVIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNVRPDSGAKRAAEAENVDMRLHRVIYNVIEEIESAMKGLLDPEFEEQVIGQAEVRQTFKVSKVGTIAGCYVTEGKITRNAGVRIIRDGIVQYEGELDTLKRFKDDAKEVAKGYECGITIENYNDLKEGDVIEAFEMVEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAG_ECO57
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPSB_THYCA
Sequence: MATLSMQVSILSKQVKNLNSFGMRASKLPMVARRVDVSTTRLRPICSASLQVEEETRRSGNYQASIWDNDFIQSFNTNKYRDEKHLNRKEELIAQVKVLLNTKMEAVKQLELIDDLRNLGLTYYFQDEFKKILTCIYNDHKCFKNEQVGDLYFTSLGFRLLRLHGFDVSEDVFSFFKNEDGSDFKASLGENTKDVLQLYEASFLVRVGEVTLEQARVFSTKILEKKVDEGINDEKLLAWIQHSLALPLHWRIQRLEARWFLDAYAARKDMNPLIFELGKIDFHIIQETQLEEVQEVSRWWTNSNLAEKLPFVRDRIVECYFWALGLFEPHEYGYQRKMAAIIITFVTIIDDVYDVYGTLDELQLFTDAIRKWDFESISTLPYYMQVCYLALYTYASELAYDILKDQGFNSISYLQRSWLSLVEGFFQEAKWYYAGYTPTLAEYLENAKVSISSPTIISQVYFTLPNSTERTVVENVYGYHNILYLSGMILRLADDLGTTQFELKRGDVQKAIQCYMKDNNATEKEGQEHVKYLLLEAWKEMNTAMADPDCPLSEDLVDAAANLGRASQFIYLEGDGHGVQHSEIHNQMGGLIFEPYV
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents (PubMed:23624978).  Monoterpene synthase which catalyzes the conversion of geranyl diphosphate (GPP) to gamma-terpinene (PubMed:23624978).
What are the official names of this protein?
Gamma-terpinene synthase, chloroplastic, Terpene synthase 2, TcTPS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMA_RHOOB
Sequence: MSDAEVPPAARGQAALLGPAEVRALAEEFGVRPTKQLGQNFVHDANTVRRIVATAGVGREDTVLEVGPGLGSLTLALLDVVDRVIAVEIDPNLAARLPVTVADRAPDLADRLTVVGADAMRVKPSEIPGEPTALVANLPYNVAVPVLLHLFSELPSLRTALVMVQAEVADRLAASPGSKIYGVPSVKANFFGAVRRAGAVGRAVFWPVPKVESGLVRIDRYAEPPWPVDDENRRRVFAVIDAAFAQRRKTLRAALGGWAGSPAEAERRLLEAGIPPSSRGETLDAAAFVRLAATHP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOP_PSEAE
Sequence: MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEARLNALLRRSSGFVQSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFTERCR
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ that plays a role in the regulation of resistance towards polymyxin B and cationic antimicrobial peptides in response to limiting concentrations of Mg(2+) (PubMed:10564474, PubMed:11021929, PubMed:24994873).  Functions as a transcriptional activator by direct binding to a cis-acting sequence upstream of the target gene promoters including oprH and pmrH promoters (PubMed:16707691).
What are the official names of this protein?
Two-component response regulator PhoP.
Protein: FABH_ECO24
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPA_BACSU
Sequence: MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS
What is the function of this protein?
Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.  Interacts with either P-Ser-HPr or P-Ser-Crh, leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre).  Binding to DNA allows activation or repression of many different genes and operons.
What are the official names of this protein?
Catabolite control protein A, Glucose-resistance amylase regulator.
Protein: FTHS_THEVO
Sequence: MRDIEEILHEMGLSKDDYELYGRYMAKLSLNLQEVNKKKAKLILVTAMTPTAAGEGKTTTTIGLGQAFKKLGKNVAIAIREPSLGPCFGIKGGATGGGKSKVEPSDRINLLFTGDFPAISAAHNLLSAMINNHIYHGNELNLDPKRITFPRTIDMNDRSLRSIVVGVGPRDMGAIANDNFVITPASEVMAITGLSLNYKDLKEKLSRILAGFTVKNKPVFAADLKAEGSMAALLRDALKPNLVQTTEGVPAFVHTGPFGNIAHGTSSIVADRIAMNLFDYVITEAGFGSDLGAEKFFNIVSRIGNLPINAVVLVATIRALKLHGGSKKQGEDVEAVKEGSKNLLRHVANIRKFGVEPVVALNKFPTDTENEIMAIGEILDSHGIKWALSEVFEKGGEGGIELANKVLSSIGDYQIKRTYEVREDLKTKIEKIAVNVYGADGVIFEKKALNDLKKAEEIMNDPYVCMAKTQYSFSDDASLLNDPHGFKVRVQSVNISSGAGFVVPILGEIMTMPGLPKRPAAENIDLAEDGEITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DATI_YEAST
Sequence: MAKTLAQGRKPGSGRKPGKGKTLREGRKPGSGRRRRQDTGGKETDGSQQDQESRLISSRDMEAVDALRELTHSPSSHSAHNSSAAPPPHAAAASTSLPPSLDYTHQSFMDQQQQQQQQQQQQLLQQQRVDVVPPKPFITHKILLSSTGNSGGHVNSNYNADHSINHNSNHNLNSNVNVNMNFTINGSNQDPSSSFLMGPYNYLQRPFIVKPYLDLSTSTAASNQPRTQPSPAAHITKNSDSTEKNATI
What is the function of this protein?
DNA-binding protein that recognizes oligo(A). oligo(T) tracts (A. T DNA).  Can bind to any 11 bp sequence in which 10 bases conform to an uninterrupted oligo(A). oligo(T) tract.
What are the official names of this protein?
Oligo(A)/oligo(T)-binding protein, Datin.
Protein: CIDA_STAAW
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIA40_YEAST
Sequence: MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP
What is the function of this protein?
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Forms a redox cycle with ERV1 that involves a disulfide relay system.  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.  The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.  Reduced MIA40 is reoxidized by FAD-linked sulfhydryl oxidase ERV1.
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40, Mitochondrial import inner membrane translocase TIM40.
Protein: CMOB_KLEP7
Sequence: MIDFSNFYQLIAKSPLSHWLETLPAQVAAWQRDALHGKFREWERAVEFLPELTPWRLDLLHSVTAESETPLSEGHQRRIENLLKNLMPWRKGPYSLYGINIDTEWRSDWKWERVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALEAFDTVFSMGVLYHRRSPLDHLWQLKDQLAPGGELVLETLVVEGDENTVLVPGDRYAQMRNVYFIPSAAALKMWLEKCGFIDVRIVDACVTSTEEQRRTEWMTTESLADFLDPQDQRKTVEGYPAPLRAVIIATKPETQQSLAKKAR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: DCOR_SCHPO
Sequence: MPAIMEKNMLVSESLRTTELLGHVKPIDSVVTWSSPGSSRQAIGEAFKNTIEEIERAAVRGEPADSDAFFVADLNGVYRQLLRWHAKLPRVQPFYAVKCNPDPKVLALLNKFGTGFDCASKGELEQILGLGVSPDRIVYANPCKAITYVRYAASKGINLMTFDNADELYKVKQHHPNSRLLLRISTDDSNSLCRLSLKFGASLDDTGKLLDIAKSLELNVVGVSFHVGSGSYDPSAFLDAIQRSRQVFDQGLERGFNFDLLDIGGGFMNDSFDGVADLIRSALDTYFDPSIRVISEPGRFFVSSSFTLAVNVIAKRKLDDEEKVMYYVNDGVYGSLNCILFDHQHPVARVLKCGSRFVYNDLVGTGQHRCFIWGPTCDSLDVIANDAHLPYELNVGDWIYFEDAGAYTVAAASCFNGFKTSRIVYLDTDILD
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
What are the subcellular locations of this protein?
Cytoplasm.