PharMolix/UniProtQA huggingface dataset:
Protein: NELFD_DROME
Sequence: MEVEYDDSGWQGRAKGQTNPEETLEDNPQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQSGGSPEEVISMLSENYKAVAQMANLLAEWLILAGVKVTEVQAMVENHLKEMILKSFDPKKADTIFTEEGETPDWLTEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSISTAAQQIEVFSRVLKTSIVKFLNNPDDVHGAIQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFNMKRLSQEIIKYALQNNQNVTPITMALNGSAVYPQACQALTSMLTRNTLNPADITVLFRNYSGSDPPPIDLIRNPQFLELLVDALFRSGVKINPEHKPKYMFLLAYASAVIDQPAKKRPMTERMLNKEELKSTIQAIEKAHTICNVDQGSTELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSYFKLSTDSCPTHLAVLDEVAAVHPTLQQQILFLLIRLFESKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYIKQCCAIEDTDISLIRYFVTEVLETITHPYSPEFVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHYTTV
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II.  The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing.
What are the official names of this protein?
Negative elongation factor D.
What is the protein family that this protein belongs to?
Belongs to the NELF-D family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with polytene chromosomes. Associates with the hsp70 promoter when it is inactive, but not when it is activated. The NELF complex possibly dissociates from chromatin following phosphorylation of RNA polymerase II.
Protein: CAID_SALEP
Sequence: MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDDPELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGSGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVMTGRRMSAEEALRWGVVNRVVSQSELMDSARELAQQLVNSAPLAIAALKEIYRATSEMPVEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: PRVB1_MERPA
Sequence: AFAGILADADITAALAACKAEGTFKHGEFFTKIGLKGKSPADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVDEFAAMVKG
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 1.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: CTSRT_MOUSE
Sequence: MELPPPGNRRVSINNPQETSGRVPTTSAGFPTQSSKISLKRSTYAYRPSMMSNRSSGGQSLLPSSILQKTSLNPPGSLQSKPSNLSSVHYADEEGKPLTDKNKDKDKGRGKGKGTGTRLLTMLRKTLQGSQSDEMAIANQTPNLIPFGDVVGCLAIHIKSCRQFSQRFLGQQRFNLFMRVSINNIVKCTKIRHLKAVNNEKNLVLRFGEMKYFSVQVPRRQDDERNFIYLELMHDGGDPESPPIPLGGAESHLYEVIQKGCFTEVMHLMHKNSSICRVEVEFMFSYGNFGYGFSHQLKPLQKAIEPSMFMNIAPPPERTDPVTNVITPQRVEYPAFLSPEFNVSIGVPEASHATVVQLEKLREKPRERLERMKEEYKNMSTWIEKADYLRNLINPKMTKRDNKGSSIPSESNSSALEELERTTYDIHHRKYEAISNEYGDKEGRVIPVLKVLDQNYSEVFLPKSSDSTPLEDVLLPPIHSLQIVEENEMPHLPKTSEPEDRPHEERKSIVFSSDEELMPKHPSILKISSSQQENRRKMEKSPHFSDVLIIPDKPFEDLNTNKKGRPPIELRKSWERHPTDVACSLRKVAFAQKDYTIPVCKAETTEFKPKHQFQKLSKSGLDPFLRNINSKMSFRKKKDHDDGYRNLSTSSAEILEHEDQDPPYPGHSGSAGSDATWAENPSPVTVQMVNRDSLPPDLITATIVISDRKNKLSLDSVFNSANSLNTKSIFASDNPVVSLTKLSDSDNKLITDSSFNTTKPSNRRLSKDSNFNTTKPSDRKLSSDPSSNTTKPSDTKLFSDPSSNKLSQGPSSNASQLSGSNRLSHNPSINGNKSSYTSDLNKVSRDPSIVSTISSDPNKLSRDPSFVLAKSSDPNKLSHYPSIISAKSSDPNKLSHDPSFVSARSSDPNKLSHDPSIISARSSDPIKLSRDPSFVSARSSDPNKLSHDPSIISARSSDPNKLSRDPSINSTKLSDPSKLSRDPSIFSTKSSDPNKLYRVPSIISGMSSNPKLSRDPSIISGMSSDPKLSRDPSIISAKSSDPNKLSHDPSIISGMSSNPNKLSHDPSIISMKLSDMSKLSRESSINASKSSDTNQLSYDPNIISAKSLDSNNSSASSSPTVNSDTTTNAAEPSGTKNMLDPVVSTIDSSDKQSKLEWLPNVQGASSVTENINTHRSSNSVNFTSDIDILKQSIVLKSILSKNLQDLSDELFSKSELYTNDEGYSPPPSVHSRPSDSTDDRVLGKVQDLNSWRSSKDLLNSQVLLSPVVKNSPQDLLPEGEPGKSSDIEDYVSEKLLEAAGRNFPMNRKSSFKKKHLVSEESSSEHVLSGSIYEYVIKQIFTAPIFSQLGIGIKSSSEARMDSQNQLLTPWERSVTSHIINYEEKDSDVNLSQSKSIISQIIQSFPVNTLLESGVIKVIELDKEHQNSLLDSQTTSSTEQYSDSRSQIKLLSRQNTSSINPLDSSVSGAEYTEDCQSISTQESKYPVRDTKSDSPNDTEEMELDSNLESSSSSLDKVKDTDTAKLKNILKNIFSIFFKYNQSERRQQPEKDSESLIKHSSSSGSEHLEKTQENFNKADKKVDRKPILNPKLRMFLEKLSETEVKNLKSELSKHIQHYLVERLTESGHITKEDLPTIYHKLYLMNEKVELKEQTPFQEKYSETVKEIMSFVNNFNHHFIDKHLETKLRGFLSEILQNYFLKNLSVSNLFNETDAMALHASMSPVRSKSELGQDIADGNFGSSLKINMQYPVTKSLQHYLQDLSENELLSLKTDLSKYLQVLFIEKLYKSGLVSERQLKGISQEIISLHSPSIPLKHIKTNLPFRNESYFMREDSEEQMKYLKNGQNAALHVLLKDKCGETELSRKKERESSFSQILKENLPAIWEQKNIYTREEETLNLIQMQSFLNKNNQANPLTRSPERPSDISLKKQKKDHGFMQFTQVEGSVYKTEIQDPYSWDSRSKTIQSKPCLEKTLKMKLLDKRENNNFYKLTAQEKLDTEFSSYLKLPNCKIPKEKEPISRLSFPTWKTNTFIHVKPEIGEQSKLDHYYQRLKGNNNNNKKHLVTFAQFKNEMETLYRNPYEACNEKRAKISESQSFKYKEKEKSSRPFFFPEVLKRENTKSKRKERDHATKPKKSFHKIVRLLPATLPTTRPHLRKSAPRNLLHWTARRTIHDCLDRFDDLHAPTVKCPKKSKSGARLLGKSPEDSHNQAKHCARPYTAPEPNKRRESAAWKFASPRMVSAGLLHLYVTPAYGIRKVRSKRKLKEDIEKRPLISEIIQMLDNAE
What is the function of this protein?
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.  Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.  Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains.  Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins.
What are the official names of this protein?
Cation channel sperm-associated targeting subunit tau, CatSper-tau, C2 calcium-dependent domain-containing 6.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane. Note=Specifically located in the principal piece of the sperm tail.
Protein: SPA6L_MOUSE
Sequence: MRFVKVFEEAIDPGAVAELLESFLTRFELVQLVSPAWEELAYYEKNTRDFLFPEPRLASSHLGMQREVLMKTAIWFPGIAPKIEFSTRTAILECVFPCKNRFICEERCRLERSVSKSHGQRVQATNRKKKPKEKDSDQLPKGTQSRLPSPQRLHLHRPTQRNHGKSFKFPGERKPPFVVRHVDSGNPFGENNLEHCSKKSRRKPKLINFDLSKKRASSLDSLEANIKVIREPDERIVLKSQPPPPVDSSESRKPSLSHQGDASLHTETSVTTSQLSRPPSPLNQPLLQERFQPFSQSTWQKIPEGVRSLLTSHRAHPKDSFISETNSIHERPSYPLKKHLLRAQRYF
What are the official names of this protein?
Spermatogenesis associated 6-like protein.
What is the protein family that this protein belongs to?
Belongs to the SPATA6 family.
Protein: RR4_DIPFO
Sequence: MSRYRGPRVRIIRRLGALPGLTSKTPQLKSNSINQSASNKKISQYRIRLEEKQKLRFHYGITERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNILFRLGMAPTIPGARQLVNHRHILVNDRIVNIPSYRCKPQDFITIKERQKSQGIIVKNMDLSQKYKIPNHLTFNSLEKKGLVNQILDRESIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RX_HUMAN
Sequence: MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEHIQAIGKPWQAL
What is the function of this protein?
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.  Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
What are the official names of this protein?
Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_COPPD
Sequence: MTREEAKKRIERLRELIEYHNYRYYVLDSPEISDEEYDKLYRELVTLEKQFPEFITPDSPTQRVGAPPAKEFATVTHEVPMLSLDNAFTEDEIKAFDQRVRSALNQQHVEYFCEHKLDGLAVSLLYENGLFVRGSTRGNGYVGEDVTANLKTIKTIPLRLKGENIPPVVEIRGEAFMMLRDFEALNEQRQALGQPLFANPRNAAAGSIRQLDSSITAQRKLYFMPYGFGLVQGMDFETQERFLKQCQEWGFRINEHNRKASSIEEALEFIRYWTEHRVELPFPADGVVIKVNNLRYWDILGTTAHAPRYAIAYKFPAEEKETKLKDVVFQVGRTGIITPVAMLEPVVLDGATVSRATLHNFDIVRQLDVRKGDVVKLKRAGMVIPEIIGVAAEKRTGKEEQIEPPTTCPVCGGPTEWDGAYLKCVNITCPAQLKGHLLHWASRDAMDIDGLGESIIENLVDMGLVKNIADLYKLSVQDLLTLPRLAQRSATKLYENIQRSKDRPFFRVLYGLGIPRVGLKTAQMLAEHFGSINALLNATMDELTSIEGIGTDTAETILKALQSPQVHELIDQLKTLGLKMEQESIEGPLKGLTFVFTGTLTSMSRGDAAKLVQSLGGKVASSVSKNVDYVVVGEDPGSKLDKAQKLGLTIIDEEAFLKMVKREHNG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: BAG6A_XENLA
Sequence: MAANEKMEVTVKTLDSQTRTFTVETEISVKDFKAHISSDVGISPEKQRLIYQGRVLQEDKKLKEYNVDGKVIHLVERAPPQTQPSTGGPSTSSSTSPTSSNAAPVPGAPERNGNSYVMVGTFNLPHVMSGLVRQQRPSVSTVNGNDGSTLDVHINLDQQLPVQSEPRVRLVLAQHILQDIQRILDRLEGQAVNEQAAEPMDTAESEGEASSRETLPQTTQNTDGQSNTTPTSHPSPSEYVEVLQSLSRVEERLAPFMQRYREILSSATSDAYENQEEREQSQRIINLVGESLRLLGNALVAVSDLRCNLSSASPRHLHVVRPMSHYSGPMLLQQAAIPIQINVGTTVTATGNGTHAGHMPSDGNAAQPPSTNTSEPQRPNTENQPPSNGERPASDAPPTSVPHPHPRVIRITHQTVEPVMMMHMNIQDSASGGPTTIPPPTAGHGGSAHIHMPGLPPEFMQAISHQITQQAMAAASGQQIPGFQAPPRFVFTRPAAPSFQFQPGTATTPPGPGGATTTVPGATVGPAGNASLAQMISGLVGQLLMHPVVVAQGGSSTSSSTSSSTFTSTSSSASSSSSTDTTSTTTTSSTANPTVSSVPSSQPPPGTDQHLSQLLGSLLGTASSGMSNITMGSPSITVTVPGMPAFLQGVTDILQATQTVPVSTAPTQSASQAPPPSSPPPPPAHSSPPPAAAPESLPPEFFTSVVQGVLSSMLGSLSAADQSGTESIAAFIQRLSGTHNIFQPDAEGPGGFFGDLLTLICHNFSLVDMVMLLHGHSQPLQNLQPQLRSFFLQEYLHQVDPTPNNIQMASRNLTNGLEEYIRESFASVTVRDDVDITRTNIEFLQDQFNRITTHILHCADSTFGQRLLEMCNQSLFEWLALNLYCLRGDQNALTSVINERIRRLSLDVSPVLVSWVTSVLSLRLQVLLGQMPVTEGEIQRHVRRVGDAPQVPEPSSQEQPMETMPVDCQNGAASPVLATHSGGVLFLPPQSSVPTICPDSDHPTQEDGGSEQWAASVPPEWVPVIRQDMQNQRKIKQQPPLSDAYLSGMPAKRRKTMQGEGPHLSLSEAVSRAMKATGAKPESSAECVRRELDNSEAQGRYREQLCQDIQKTLQDNESYSAQRFPNTQRAFRGDP
What is the function of this protein?
When nuclear, may also act as a component of some chromatin regulator complex.
What are the official names of this protein?
Large proline-rich protein bag6-A, BCL2-associated athanogene 6, HLA-B-associated transcript 3-A, Protein Scythe.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome.
Protein: NDH_ECOLI
Sequence: MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAAAHNELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH
What is the function of this protein?
It may also contribute to copper homeostasis and bacterial oxidative protection (PubMed:7487066, PubMed:10510271, PubMed:16759635, PubMed:21390523).  Shows cupric reductase activity, and catalyzes the reduction of Cu(2+) to Cu(+) with NADH as electron donor (PubMed:10510271).  Exhibits Cu(2+) reductase activity in the presence of either FAD or quinone, but is unable to reduce Fe(3+) (PubMed:10510271).  Contains thiolate-bound copper (PubMed:12176061).
What are the official names of this protein?
Type II NADH:quinone oxidoreductase, Cupric reductase, NADH dehydrogenase-2, NADH dh II, NDH-2, NADH-quinone reductase, NQR, NADH:ubiquinone oxidoreductase, Respiratory NADH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Membrane-bound (PubMed:10664466). Interaction with the membrane is probably mediated by amphipathic helices and electrostatic interactions (PubMed:15581635). Copurifies with phospholipids (PubMed:7020757, PubMed:6362717).
Protein: MYOA_PLAFB
Sequence: MAVTNEEIKTASKIVRRVSNVEAFDKSGSVFKGYQIWTDISPTIENDPNIMFVKCVVQQGSKKEKLTVVQIDPPGTGTPYDIDPTHAWNCNSQVDPMSFGDIGLLNHTNIPCVLDFLKHRYLKNQIYTTAVPLIVAINPYKDLGNTTNEWIRRYRDTADHTKLPPHVFTCAREALSNLHGVNKSQTIIVSGESGAGKTEATKQIMRYFASSKSGNMDLRIQTAIMAANPVLEAFGNAKTIRNNNSSRFGRFMQLVISHEGGIRYGSVVAFLLEKSRIITQDDNERSYHIFYQFLKGANSTMKSKFGLKGVTEYKLLNPNSTEVSGVDDVKDFEEVIESLKNMELSESDIEVIFSIVAGILTLGNVRLIEKQEAGLSDAAAIMDEDMGVFNKACELMYLDPELIKREILIKVTVAGGTKIEGRWNKNDAEVLKSSLCKAMYEKLFLWIIRHLNSRIEPEGGFKTFMGMLDIFGFEVFKNNSLEQLFINITNEMLQKNFVDIVFERESKLYKDEGISTAELKYTSNKEVINVLCEKGKSVLSYLEDQCLAPGGTDEKFVSSCATNLKENNKFTPAKVASNKNFIIQHTIGPIQYCAESFLLKNKDVLRGDLVEVIKDSPNPIVQQLFEGQVIEKGKIAKGSLIGSQFLNQLTSLMNLINSTEPHFIRCIKPNENKKPLEWCEPKILIQLHALSILEALVLRQLGYSYRRTFEEFLYQYKFVDIAAAEDSSVENQNKCVNILKLSGLSESMYKIGKSMVFLKQEGAKILTKIQREKLVEWENCVSVIEAAILKHKYKQKVNKNIPSLLRVQAHIRKKMVAQ
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Myosin-A, PfM-A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Tightly associated with the plasma membrane.
Protein: YCEH_ECOHS
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: MOAA_CAMJ8
Sequence: MLIDQFGRKINYLRISVTQRCNFRCLYCMPKIPFDYQPKENLLSFEELFLFVKAAIDEGIEKIRITGGEPLLRKDLSIFIKMISDYKSDIDLAITTNGFLLKDFAKDLKNAGLKRLNISLDTLDHKKAKTLAQKDVLDSVLSGIDEALNLDLKVKLNTVALKNLNDDELISLLEFAKSKKAQIRFIEFMENTHAYGKLQGLKRDEIIQILSQKYQIQLIKKDEKAPVSIYKADDYEFGIIDPHSHEFCDSCNRIRLSAEGLLIPCLYFDEALSIKEAVRKGDIKAAVEILQEVLRNKPEKNKWSVVDNETSSRAFYQTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PYRH_ACISJ
Sequence: MTLATPAHKRILLKLSGEALMGDDAFGINRATIVRMVEEIAEVTRLGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATVMNALALADAMDKQGLTARVMSAIGIEQVVEPYVRPKALQYLEEGKVVVFAAGTGNPFFTTDTAAALRGAEIGAEVVLKATKVDGVYTADPMKDPSATRYAKLTFDEAMSRNLGILDATAFALCRDQKLPIRVFSIVKHGALKRVVMGEDEGTLVYA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCSF_ECOL6
Sequence: MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPRYVKPAGTLRRTEKARATKK
What are the official names of this protein?
Cellulose biosynthesis protein BcsF.
What is the protein family that this protein belongs to?
Belongs to the BcsF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IF2_GEOSW
Sequence: MSKMRVYEYAKKNNVPSKDVIHKLKEMNIEVTNHMATLEPEVVEKLDHTYNKKNERPQASAPKEKQKAPVKPKNYVDDFDDEDEEVVKTKVPKKKSANKKKEGKKHDLQLQQQEKKIFHQQKKKIKGKAKAKEQQPVQQEQPMKKEKELPKKITFEGTLTVAELAKKLGREPSEIIKKLFMLGVMATINQELDKDAIELICSDYGVEVEEKVVIDETNFESIEIVDDPEDLVERPPVVTIMGHVDHGKTTLLDSIRHSKVTEQEAGGITQHIGAYQVTVNDKKITFLDTPGHEAFTTMRARGAQVTDIVVLVVAADDGVMPQTVEAINHAKAANVPIIVAINKMDKPDANPDRVMQELMEYNLIPEEWGGDTIFCKLSAKTGEGIDNLLEMILLVSEMEELKANPNRRATGTVIEAKLDKGRGPVATLLVQAGTLHVGDPIVVGCTYGRVRAMVNDTGRRVKEAGPSTPVEITGLHEVPQAGDRFMVFEDEKKARQIGEARAQKQLMEQRNMKARVSLDDLFEQIKQGEMKELNIIVKADVQGSVEALVAALQKIEVEGVRVKIIHAAVGAITESDILLATTSNAIVIGFNVRPDANAKRVAESEKVDIRLHRIIYKVIEEIEAAMKGMLDPEYEEKVIGQAEVRQTFKVSKVGTIAGCYVTDGKITRDSKVRLIRQGIVVYEGEIDSLKRFKDDVKEVMQGYECGLTIKNFNDIKEGDVIEAYIMQEVERK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM4D_MOUSE
Sequence: MRMCAPVRGLFLALVVVLRTAVAFAPVPRLTWEHGEVGLVQFHKPGIFNYSALLMSEDKDTLYVGAREAVFAVNALNISEKQHEVYWKVSEDKKSKCAEKGKSKQTECLNYIRVLQPLSSTSLYVCGTNAFQPTCDHLNLTSFKFLGKSEDGKGRCPFDPAHSYTSVMVGGELYSGTSYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIQKSPDGPEGEDDKVYFFFTEVSVEYEFVFKLMIPRVARVCKGDQGGLRTLQKKWTSFLKARLICSKPDSGLVFNILQDVFVLRAPGLKEPVFYAVFTPQLNNVGLSAVCAYTLATVEAVFSRGKYMQSATVEQSHTKWVRYNGPVPTPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPKLIKKDVNYTQIVVDRTQALDGTFYDVMFISTDRGALHKAVILTKEVHVIEETQLFRDSEPVLTLLLSSKKGRKFVYAGSNSGVVQAPLAFCEKHGSCEDCVLARDPYCAWSPAIKACVTLHQEEASSRGWIQDMSGDTSSCLDKSKESFNQHFFKHGGTAELKCFQKSNLARVVWKFQNGELKAASPKYGFVGRKHLLIFNLSDGDSGVYQCLSEERVRNKTVSQLLAKHVLEVKMVPRTPPSPTSEDAQTEGSKITSKMPVASTQGSSPPTPALWATSPRAATLPPKSSSGTSCEPKMVINTVPQLHSEKTVYLKSSDNRLLMSLLLFIFVLFLCLFSYNCYKGYLPGQCLKFRSALLLGKKTPKSDFSDLEQSVKETLVEPGSFSQQNGDHPKPALDTGYETEQDTITSKVPTDREDSQRIDELSARDKPFDVKCELKFADSDADGD
What is the function of this protein?
Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (By similarity).  Regulates GABAergic synapse development (PubMed:23699507, PubMed:29981480).  Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (PubMed:23699507, PubMed:29981480).  Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (By similarity).  Promotes the migration of cerebellar granule cells (PubMed:17554007).  Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (By similarity).  Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (By similarity).
What are the official names of this protein?
Semaphorin-4D, M-Sema G, Semaphorin-C-like 2, Semaphorin-J, Sema J.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MIAA_STRPN
Sequence: MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLDIGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRALEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHSPNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIGESGVQDRILSQIEEFLDD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RRT14_CANAW
Sequence: MSFNSNASKYQAENTVDKLFSNILHTSTTSKSVSKSKSKSKSKPKPISSTQLLVNQLQSTNTTANNNNTKRKKHNNNKRINKTLLEEKKFSKFIKYNHIKQKSNKSELDEKYLNKLVRKNINSLNKINKIDDLLIDEELNQIKQELLEENEFVGMGGGQLKGGKRLRKKLLNNTKQVIDEFDGFGEISSSNNNNKKKNSSHPGLTPGLAPVDYEEEDDE
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS3A_TAEGU
Sequence: MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGGAGKPSGDEAGTKVERADGYEPPVQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May play a role during erythropoiesis (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_GUITH
Sequence: MSKIILYQEDARRALERGMDILAEAVSVTLGPKGRNVVLERKYGAPQIVNDGVTIAKEIELEDHIENTGVALIRQAASKTNDVAGDGTTTATVLAHAMVKQGMKNVAAGANAIALKRGIEKATQFIVTQIAEYARPVEDTRAISQVASISAGNDIETGKMIADAIDKVGREGVISLEEGKSTITELEMTEGMCFEKGFISPYFVTDTERMEVIQDNPYILLTDKKITLVQQELLPTLELISKTSRPLVIIAEDVEKEALATLVVNKLRGIVNVVAVRAPGFGDRRKAMLEDIAILTGGQVISEDAGFSLETLTLDMLGQARRITITKENTTIIAEGNEKDVKSRCEQIRRQIEASDSSYEREKLQERLAKLAGGVAVIKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGSTLTHLANDLKDWAEDNLIEDELIGALIVERSLTSPLRRIIENTGQNSAIIIEQIKESEFNIGYDAAKGEIVDMYDVGIIDPAKVTRSGLQNAASIASMILTTECIVVDKQDEK
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, chloroplastic, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPL_ALIF1
Sequence: METLLSFSAIAVGIIVGLASLGTAIGFALLGGKFLEGAARQPEMAPMLQVKMFIIAGLLDAVPMIGIVIALLFTFANPFVGQLAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.