PharMolix/UniProtQA huggingface dataset:
Protein: ARGJ_TALMQ
Sequence: MVVLFKAGSLGPATNSFIIAATRRGQIRLYNILQDTTIPEPKRKYIPSSGTYPKGFRVSGTHVGVKAANTKYPDLALISSDKPCTAAAAVFTTNKFQAAPVQLSKVTLEQRKGKGIQSVVINSGCANAVTGKGGLEDARSMAAKVDECNGTSEPSTLVMSTGVIGQRLPISKILDKIPTAYSNLASTHNAWLATARAICTTDTFPKLISRTFSLPSSPGITYSLAGMTKGAGMIHPNMATLLGVLCTDAPVDASVMKPLLLHAVSRSFNSISIDGDTSTNDTIAFLANGAAGGQTIASSTSQDYAALQKVLTSFAQSLSQLVVRDGEGATKFVTVRVQNSPCYDSARRIASTIARSPLVKTALYGRDANWGRILCAVGYTDGVTEGTVVPERTSVSFKPVDGSPTLRLLVNGEPEVVDEERASAILQDEDLEIIVDLGGGDKGEKGLGGEEAVYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CAP1_PIG
Sequence: LEAVSHASDTHYGYGDSAAKEIGGDVLKHAEMVHTGLKEYKDVDKXGPVAKELSGLPSGPSAGSGPPPSALFAQIHQGESITHALKHVADDEKTHKNPADKAQSGPVRXGPKPFSASKPGISPSPKPVTKKWRXENXENVSNLVIDDTELKSVNSTLQIKXXINSISVDNYKVPXISINKXDGRHIYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQXKXIWNGQK
What is the function of this protein?
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
What are the official names of this protein?
Adenylyl cyclase-associated protein 1, CAP 1, ASP-56 protein.
What is the protein family that this protein belongs to?
Belongs to the CAP family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OFP11_ARATH
Sequence: MSNFLRKKLHLCFSSSGGLSPSIPSSPIIVSNHNAQSHPHHTPSIFINNFNSLYDQLSVSSPLHRRHSSENPAGVFSTNRREEEEEDETTTSVSKLLSGGTAIMKHIESPDPYRDFGRSMREMVEARDLTRDVVADREYLHELLFCYLYLNPKHTHRFIVSAFADTLLWLLSPSPSPEHFLS
What is the function of this protein?
Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
What are the official names of this protein?
Transcription repressor OFP11, Ovate family protein 11, AtOFP11.
What are the subcellular locations of this protein?
Nucleus.
Protein: PALH_MAGO7
Sequence: MDPLEARQLIPAAPGSDDEGRTSRARLCQAVNLPANGALVMPNGEVITLTAPAAFKPACAPNTTPAIIAGPGGTTGAGVDDAAHVGPQFSDLSDPFYASTFPQCYALAATTVIAYTLVIMLVITPRSFLDGGIVVLGRRGFTSGGSGHGIIGGRPWLQKVAALTVAISLTIATADTFKVAEQQYAFGLQNARELQDKVLNGTELKIIRIISDTFLWLAQAQTLIRLFPRQREKVIIKWTAFALITFDLIFDSLNSFQFPGPGNSRPGSFTDAIPALSYLFQLALGVLYAAWVIYYSLMKKKYAYYHPQMKNICFVAGLSLLSILVPVVFFILDISKPEFTGWGDYVRWVGAAAASVIVWEWVERIEALEREEKRNGILGREVFDGDEMLETDSDATWPQRSRATKGPHGDGDDDDDDGEGGRRIAVGDGTGRRRARRANGSHDSLAADSGRGRNHTQLWTSIASRYRSRPNNGADVSETEKDNTRQTSKNVRPAAARFLQPPLWPARPPPAATPVSRTDTASADSTVYAIRYHPLTDVHSRTTTRPTPPPQLSTERQSAVVDVSGTPTAVEDVRSHDQPSGSQSASPSPPRDQQSPGPPNLVRLSREETRRERRQSLATTSRTGTRVGPDSDDPSASSQQGGESSRGSESTAAKGWRTLAQTLPFRGGTARSAEDSSDSQSTTSKSRSKLQVSREGKSDRWDLRNRMEDFAVTQAERIRERIRPTPDTDSLPVTVIPAPARRGAALAQLLEEDESRQGSGRPRPQDDERPILGSPTLPSSGQRQNSMGPEPLSSNDDLSDSHIPPPAVVRAASRANTSRSTTRDRPPEP
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palH/RIM21.
What is the protein family that this protein belongs to?
Belongs to the palH/RIM21 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALG_SALTI
Sequence: MAMVQPKSQKLRLFITHLGLLIFIAAIMFPLLMVIAISLREGNFATGSLIPDKISWEHWRLALGFSVEHADGRVTPPPFPVLLWLWNSVKIAGITAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLNTHGGVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVDSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITLVFLLAQRWLVNGLTAGGVKG
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltose/maltodextrin transport system permease protein MalG.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MPK13_ORYSI
Sequence: MEFFTEYGEASQYQIQEVVGKGSYGVVAAAVDTHTGERVAIKKINDVFEHVSDAIRILREIKVLRLLRHPDIVVIKHIMLPPTRREFRDIYVVFELMESDLHQVIEANHDLSPEHHRFFLYQLLCALKYIHSANVFHRDLKPKNILANSDCKLKICDFGLARVAFNDSPSTIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEILTGRPLFPGRNVVHQLDLITDLLGTPSSETLSRIRNENARGYLTGMQRKHPIPFSHKFHNADPLALRLLERLLAFDPKDRPTAEEALADPYFRGISKLSREPSRLPVSKFEFEFERRKLTKDDVREMIYREILEYHPQMLQEYIRGGEQISFLYPSGVDRFKRQFAHLEENYSRGERSTPLRRQHASLPRERVCSSVDSNNQDSDNEERRAISSIARTMISPPRSQEKGKNRASAYPNGIINLNSNPKIYLKSASISASTCIIRGNKGPKENGISEDMEEVVYELSDNVTRMLS
What are the official names of this protein?
Mitogen-activated protein kinase 13, MAP kinase 13, Benzothiadiazole-induced MAP kinase 2, MAP kinase 2, OsBIMK2, OsBWMK2, OsMAPK2, OsMPK17-2, Wound- and blast-induced MAPK 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: NUOC_MYCBT
Sequence: MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BPT_LEPCP
Sequence: MTHPKELPLAQLQFYATAPYPCSYLADRMARSQVATPSHLINAETYSGLVAAGFRRSGMFTYRPYCDGCQCCVPLRVPVNDFAPSRSQRRAWKQHQGLQARVMRLCFVPEHYALYLRYQNRRHAGGGMDEDSVDQYTQFLLQSRVNSRLVEFREPGIGDQPGALRIVSILDVLNDGLSAVYTFYEPDPACSYGTYNVMWQIAQARELGLPYLYLGYWIEASAKMAYKSLFQPHEMLLGGTWQRQPAR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y112_ALCBS
Sequence: MSMENSPLKYQLLVAMPQMADPDFEHSVTYIVEHSSEGAMGLTLNRPVQISLGDILSDMDIEIEVPPSERHRVVAGGPVQQEAGFVLHSAATRWHASIPLSDGLILTTSRDILEAIAIGEGPEQSLICLGYAGWDAGQLEQELVDNAWLSTPASRELVLETPFEQTWHAAAARIGVDMSLIATQAGHC
What are the official names of this protein?
UPF0301 protein ABO_0112.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL33_CAMJE
Sequence: MRIKVGLKCEECGDINYSTYKNSKNTTEKLELKKYCPRLKKHTLHKEVKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: UPPP_BURM9
Sequence: MDWILICKALALGIVEGLTEFLPVSSTGHLIVAGSFLRFHPEQAKTFDVVIQFGAILAVCWEYRRRIIDVVTGLPAQREARRFTMNVVIATVPAVALALLFEKTIKSVLFAPVPVAVALVVGGAAILWVEGRQRERSEPARVQSIDALTPFDALKVGLAQCCALIPGMSRSGSTIIGGMLFGLERRVATEFSFFLAIPVIFGATLYETAKDWRAFNVDSVGLFAIGLVAAFVSAFACVRWLLRYVASHDFTAFAWYRIAFGLFVLLVGYSGWIEWT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YTH1_ASPOR
Sequence: MSAEVSHAASQILASGSERDPSYNDFSFIPFLRNSFGFGLACDVPVCKAYSEGHCPLGPACPDRHPTPSRVTTSTTTASGLAPSTTHGSLVCKHFLKGLCKKGLKCEYLHEYNLRRMPECQSFSRSGYCPNGDDCLYQHVREQARLPPCEHYDRGFCPLGPLCAKRHVRRRLCQYYLAGFCPEGKGCADAHARWIENLPKPSIRVEKTEEELERERILIREEQEREKEREREWRSERGRGGGFMRGRFRGRGRGL
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
mRNA 3'-end-processing protein yth1.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_BURTA
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYANQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GUAA_CUPNH
Sequence: MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDDFVREFAPKAIILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEVRAHGHTNLLKDIEDFRTPEGHGMLKVWMSHGDKVAGLPPGFKLMASTPSCPIAGMADEARGYYAVQFHPEVTHTAKGRQMLERFVLGIAGCKPDWVMRDHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRQDEGKLVMEMFVGRLHAKVVHIDASEQFLGHLAGVTDPEQKRKIIGREFVEVFQAEARKLSNAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKRDYADLLRRADAIFIEELRKTLATEQDAAAGLCEPDQVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVQTTDFMTAHWAHLPYALLGRCSNRIINEVRGLNRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL16_RHOPS
Sequence: MMQPKKTKFRKAHKGRIHGVASSGATLAFGQFGLKAMEPERVTARQIEAARRALTRHMKRAGRVWIRIFPDVPVSKKPAEVRMGSGKGAPELWVARVKPGRVMFEIDGVNQQIAREALTLAAAKLPIKTRFVARIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RIMO_PROM2
Sequence: MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINEANVVVVNTCSFIQTAREESIRKILEYTNQGKEVIVAGCMAQHFKDELIKEIPEIKGLIGTGDYQKIAKVLDRVEKGEIVNEVSKIPEFIADEEIPRFVDKNKFVAYLRIAEGCNYNCAFCIIPKLRGPQRSRTIESIVSEAKSLAKQGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVPIPWIRIHYAYPTGLTDQVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEHFEHLLEFLDRHKFDHVGVFIFSPEVGTAAFDLPNKVSPEVAEARKDNVISVQQNISKDKNQSYVGSKMKILVEKISDNNELIGRSYNFAPEIDGTVILSVKDKIDLKNYSGKFVEANISFADEYDLYGETLKIL
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_SERP5
Sequence: MTQKEIWYETLHANFGQYFSVENVLYREKTEHQDLVIFENPVLGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHQGVEQITMVEIDAGVVEFCRQYLPNHNAGAYDDPRFKLVIDDGVNFVNQTDEKFDVIISDCTDPIGPGESLFTSAFYEGCARCLNEGGIFVAQNGVCFLQQDEAVNSHTRLSQYFKDVSFYQAAIPTYYGGIMTFAWASQDPALRQLDLTTLQHRFHQSGLNCRYYNPAIHAGSFALPQYLLDALNVSR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_ECOL6
Sequence: MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQTFYNARRRQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQVLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL
What is the function of this protein?
NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins.  Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN_METAC
Sequence: MRSHLVKPGSVYDGIEPGELGESTESVQDRVRQLESRNSFLEEQCSQIESEKRYLENQKIKYEREIRKLQSELDRMKTSPLIIGTVIDVIKNDRIIVRSSNGPQFLVNVSQYIDEKKLLPGAKVALNQHTLAIAEVIPSTEEPFVAAMEVIESIEVDYDQIGGLDEQIQELQEAVELPLIEPERFARIGIEPPKGVLLYGLPGTGKTLLAKAVAHRTNATFIRVVGSELVQKYIGDGSKLVREIFEMARKKAPSIIFIDELDSIAARRLNETTGADREVQRTLMQLLAEMDGFDKRKNIRIIAATNRPDVLDPAILRPGRFDRLVHVPMPGIEARGKILKIHCGKMTLAGDIDFKKLAKVTEGMSGADLKAIATEAGMFAVRKDKALVEMEDFLEAVEKVSMAADTQKMMPGNLPETTMFV
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_BRUA2
Sequence: MTEFLPFVARHIGPRHEDERAMLAALGLPSMETLITQAVPAPIRLNRALNLPAALSEADALAELGTIMGRNVVKKSFIGAGYHGVHTPPVIQRNLFENPAWYTAYTPYQSEISQGRLELLFHFQTLVAELTGLPVACASLLDEATAVAEAIGVACRHHRDKRSRILLAGELHPQTVDVVNTRAEPLGWEIATGSDVDDNTAAIVVPWPDTRGVYGDFAKVIADAKAKGALVIAVADPLALTIMEAPARWGADMAVGSMQRYGVPMGFGGPHAAYLAVSEALTRIIPGRIVGQSVDAHGRAAYRLALQTREQHIRRDKATSNICTAQALLANMAAAFAIWHGPAGLQAIATRVAALAARFAAALKAAGVEIAGESLFDTVTAKVPGKAAAIAAEADKGGRLIRIIDADTVGVTFDETSTEEDLTALASLFGAKPVGGDTVLVPGKERGEGFLTQEVFHSHRSETEMMRFLRRLADKDLALDRAMIPLGSCTMKLNAAAEMMPVSWNTVANLHPFAPAEQVQGYAKMTSDLEAWLCEITGFAGVSLQPNAGSQGEYAGLMAIRHYHQARGQGHRNICLIPSSAHGTNPASASMAGMSVVVVNCRPDGDIDIDDLKAKAEKHRDNLAAFMITYPSTYGVFEEGIKAFCEIVHDNGGQVYFDGANLNALVGLARPADIGADVCHMNLHKTFCIPHGGGGPGVGPIGVAKHLVPYLPGHVEAGSEHAVAAAQFGSASILVITWMYIRMMGGAGLKKATEAAILNANYIAHRLKGVYPILYTGAHDRVAHECIVDTRVLKDSAGITVEDVAKRLIDYGFHAPTMSWPVAGTLMIEPTESEPKLEIDRLCDAMIAIAGEAKKVADGVWPADDNPLANAPHTASDTLATEWKHPYTREEAVFPGGAFDPTAKYWPPVSRVDNVGGDRNLICSCPPVATYG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RL27_BUCBP
Sequence: MAHKKAGGSSRNGRDSHSKRLGVKHFGGETIRSGSIIVRQRGTKFHAGNNVDCAKDHTLFATSQGKVKFEKKGKCNRTYVSIIPE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FPG_SALPA
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NCAP_CHAVB
Sequence: MSNSKEIPSFRWTQSLRRELSSFTIPVKSDVLKDAKMIADGLDFSQVALVQRVLRKTKRTDGDLDKLRDLNREVDNLMAMKSAQKNTILKLGDLNKSELMDLASDLEKLKKKVGQTERSPVGGVYLGNLSQSQLSKRTDLLRRLGFQQPQVRSTGVVRIWDVADPTRLNNQFGSVPALTIACMTVQGGDTMGNVVQALTSLGLLYTVKFPNLADLEKLAAEHDCLQIITKDESAINISGYNFSLSAAVKAGATFLDGGNMLETIKVTPDNFSTIIKTVLGVKKRENMFIDERPGNRNPYENLLYKLCLSGEGWPYIGSRSQVKGRSWENTTVDLSLKPTQGPKAPEKVGLNVRLSHLTEIQESVVREAMSKINPSHTTWIDIEGTSNDPVELALYQPESGNYILCYRKPHDEKGFKNGSRHSHGMLLKDLESAQPGLLSYIIGLLPQDMVLTAQGSDDIKRLLDTHGRKDLKVVDVKLSSDQARNYEEQVWSDFGHLCKKHNGVVVPKKKKDKDPSQSTEPHCALLDCLMFQSVIDGQPPQIKLQSLLPEVLLFTMKPAFAI
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: EFP2_CHLTR
Sequence: MVRVSTSEFRVGLRVKIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGESIETADVREQQMRLLYTDQEGATFMDDETFEQELIFWDKLENVRQWLLEDTIYTLVLYNGDVISVEPPIFMELTIAETAPGVRGDTASGRVLKPATTNTGAKIMVPIFIEEGEVVKVDTRTGSYESRVSK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P 2, EF-P 2.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BURCM
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFTDAQKYVRQLAANRGTILFVGTKRQSRDTIAQEAQRAGMPFVNARWLGGMMTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAEGVADAILEGRANAVNEVVQAARGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: UBIB_HAEDU
Sequence: MIFKNTRRSYQIIATFLRYGIDEIIPDIPFTYSARLTRKAFFWLQNEHKDQPFGVRLRLALQELGPVWIKLGQMLATRRDLFEPALADQLALLQDSVAPFDGKLARKIIEQALGNTLETWFDDFDEQALASASIAQVHTATFNKNQPLAGQNVVLKVIRPDIEHIIKADIALMYQLAKLIPYLSDDAKRLRATEVVREYEKTLLDELDLTREMANAIRLRNNFENSEMLYVPAMYPDFCHKNVIVMERIYGIPVSDIATLTENGTNMKLLAERGVQVFFTQVFRDSFFHADMHAGNIFVNPNHPEDPQYIGIDCGIVGTLNQNDKRYLAESFVAFFNRDYRRVALMHIESGWTPADTDVDAFEEAFRTVCEPIFAKPLAEISFGQVLLNLFNVARQFNMEVQPQLVLLQKTLLYIEGLGRQVYPALDLWQTAKPFLQKWLDQQVGFKAILRDLKQQAPQFREHFAQFPEAVFNALQQQKHINYRLAELNKTLQSQADNKTYNVKMIIMGSIILSLLWQFNSLPLWLSLPILTMLCLALCRRK
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SUFE_SODGM
Sequence: MANLPDKDKLLRNFSRCGNWEEKYLYIIELGGQLPPLSAEMRTPDNRIAGCQSQVWIVLSTQADGSVQLYGDSDAAIVKGLIAMVFILYQGLTLAEIVAYDVRPFFDALALTQHLTPSRSQGLEAMVRGIRAQVAARQ
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_HUMAN
Sequence: MSLVIRNLQRVIPIRRAPLRSKIEIVRRILGVQKFDLGIICVDNKNIQHINRIYRDRNVPTDVLSFPFHEHLKAGEFPQPDFPDDYNLGDIFLGVEYIFHQCKENEDYNDVLTVTATHGLCHLLGFTHGTEAEWQQMFQKEKAVLDELGRRTGTRLQPLTRGLFGGS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in rRNA maturation.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Nucleus.