PharMolix/UniProtQA huggingface dataset:
Protein: TUS_SALG2
Sequence: MSRYDLVERLNGTFRQIEQHLAALTDNLQQHSLLIARVFSLPQVTKEAEHAPLDTIEVTQHLGKEAETLALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDNATQLDLENQVQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLTLINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQDIAALPQQARLKIKRPVKVQPIARIWYKGQQKQVQHACPTPIIALINTDNGAGVPDIGGLENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_HALHL
Sequence: MKAKRMTDLDLTGKRVLIREDLNVPIKDGQVADDTRVRAAAESIRQAMQAGGRVLVMSHLGRPKEGEYDAEASMAPVARRLGEILGCEVPVVRDWLEGVDVPEGGVALAENVRFQPGETKDDEALSRRMAALCDVFVMDAFGTAHRAQASTHGVARFAPEACAGPLLSAELEALGKALDNPARPMIAIVGGSKVSGKVQVLEALTHKVDQLIVGGGIANTFIAAAGYSVGKSLYEADFVDTAKRLMEEARAKGGEIPIPEDVVTARDFSADAEAHVHPVDAVPDDEMILDVGPQTRARYDGMLRNAGTVVWNGPVGVFEMAPFAGGTRALAEAIAASDGFSIAGGGDTLAAVEQFGITDQVSYISTGGGAFLEFLEGRVLPGVAALEQHAAAHS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSOB_ECO57
Sequence: MKKDKKYQIEAIKNKDKTLFIVYATDIYSPSEFFSKIESDLKKKKSKGDVFFDLIIPNGGKKDRYVYTSFNGEKFSSYTLNKVTKTDEYNDLSELSASFFKKNFDKINVNLLSKATSFALKKGIPI
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  A labile antitoxin (half-life of 5. 9 minutes) that inhibits the endonuclease activity of cognate toxin LsoA but not that of non-cognate toxin RnlA.
What are the official names of this protein?
Antitoxin LsoB.
Protein: SYFA_PYRAE
Sequence: MLVLPLPLYEIIRHAPEWKPLEEVARELGSSVDSLMRYVEEGRAKGVLRVERKVIEFYELTEEGRQRAAEGLPEYKLLKSAVCREGRCTAHLSQHPEAQIALANLAKLGVKPRGNVVELDEETYKKIVAMLEEKQKALAAPHSAPPEVLKEFIKRKLVRKIEKTQVYVKAAVPLELVKPAEVKTVITSEDIATGRWRNYTLKPFDLNIEPPEYPAPVPHFFNEFLDYVREVMIGLGFEEVRGPVLEVEFWNFDALFQAQDHPAREVHDTFYVQWSGPLETPPEHLMESVGRVHEEKWRYKWDRKKALNPVLRTQTTATTIRALAERGDGEYKVFTIGRVFRPEKLDPKHSMEFHQLDGIVVGPGLTFKHLLGQLEEIAKALGMTKVKFRPAYFPFTSPSVEVYAQHPKLGWVEFGGAGIFRPEVTEPLGVKKSRVLAWGWGLDRIAMILLGIDDIRELFTKDLEKLKEYYARWARYKASVGAVGTLFTL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP53_YEAST
Sequence: MAPTNLTKKPSQYKQSSRKGKKAWRKNIDLSDVEQYMEKKIDHEITHGTSDITSLQNDALFHVDVEGDEILKNKLIKRKQIKKVLKSKEILDAVKTNSKIAALNHHKNSSGNPNKIQGVSKHELKKLMALAGRVHGESKIKNRVAKDGLVKTTAGDLWGEESNSKKQKVKLPSGIKLDVEKKDQIPEELLKKSTTSWSTASVRPSTLDIEPIAVKEFTEIPHAGKSYNPNNKAWSELINKEYKEEKAREDERIALEKYKERIRHLMETLDDNEEEESSSNEEEEEEEEENENENESTQCSGSDKEIKLSINKPVKNKKKTKYQRNKAKRHEEKVKLQQELKELRQRVKDLEEVINSEETEILSAIESDSNKVKKSKKNKKHKLGTKYSVIDERLEIKFSDELSDSLRKLKPEGNLLYDTVRKLQSSGKVETRVPVRKGRKYKQKITEKWTHKDFK
What is the function of this protein?
Late-acting factor in the nuclear maturation of 60S ribosomal subunits, which is required for normal acquisition of export competence.  Required for the export of the large subunit.  Acts to stimulate the RNase activity of the exosome complex, and may recruit the exosome to 7S pre-rRNA for processing.  Associates with numerous RNAs including the 27S and 7S pre-rRNAs and the box H/ACA snoRNA snR37.  Also interacts (via N-terminal region) with the mature 25S rRNA and the mature 5. 8S rRNA.
What are the official names of this protein?
Ribosome biogenesis protein NOP53, Nucleolar protein 53.
What is the protein family that this protein belongs to?
Belongs to the NOP53 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Does not shuttle from the nucleus to the cytoplasm (PubMed:16043506).
Protein: AG19_COCP7
Sequence: MKFSLLSAIAAAVFVPFTSATPLASTADLSYDTHYDDPSLPLSGVTCSDGDNGMITKGYNTAGEIPNYPHVGGAFTVETWNSPNCGKCYKVTYNAKTIFLTAIDHSNSGFNIAKKSMDVLTNGRAEELGRIKVTYEEVASSLCGLK
What are the official names of this protein?
Heat-stable 19 kDa antigen, Coccidioides-specific antigen, CS antigen, CS-AG, Precipitin antigen, TP-AG.
What is the protein family that this protein belongs to?
Belongs to the cerato-platanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SULA_CROTZ
Sequence: MYFSHQNRAHGSRRLAKETADALAQAETRGLISEVMYNEDQPRMTQMVLLPLLQQLGLQSRWQLWLTPQQRLSREWVESAGLPLTKVMQVSQMNPQVTLDSMIRALETGNYSVVIAWLHDDLTDDEHRRLTEAAEKGNAMGFLMRPVQPSLPGDRPRSGLRIHSRMVH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: Y1419_GEOTN
Sequence: MEKSFYRYLLRFRHGYEEDPVVRFANGAYDDHGFPKGSADYEELSGYLELNGDYLESMVIFDELWEQFLHET
What are the official names of this protein?
UPF0346 protein GTNG_1419.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: GDU1_ARATH
Sequence: MRPLSVQSKFEDVATSTSVNHHGVTPQSPWHSPVPYLFGGLAAMLGLIAFALLILACSYWRLSSSGEEDGQNVDEEKESRSGDKAANGAYEEKFLVIMAGEDLPRYLATPAMKKCTCGGHEGKMVISQEESVAKEEEKMREGEEEKVKDTGETTTTSH
What is the function of this protein?
Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism.  Stimulates amino acid export by activating nonselective amino acid facilitators.  Required the interaction with the RING-type E3 ubiquitin-protein ligase LOG2 to fulfill its function.  Plays a role in the Gln export at hydathodes, at xylem parenchyma into xylem sap and from mesophyll into leaf apoplasm.  Acts upstream genes involved in the salicylic acid (SA) pathway and in the geminivirus-host interaction.
What are the official names of this protein?
Protein GLUTAMINE DUMPER 1.
What is the protein family that this protein belongs to?
Belongs to the GLUTAMINE DUMPER 1 (TC 9.B.60) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RR15_LOTJA
Sequence: MVKKSFIPVISQEKKEENPGSVEFQVFNFTNKIRRLTSHFELHRKDYLSQRGLRKILGKRQRLLSYLSKKNKIRYKKLINLLDIRESKIR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECU_BACC7
Sequence: MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIIAFWNRQNTGGRKSITKEEIEEHGSLLSCGYHPRIDYIRVLDTVYFS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAV_DROME
Sequence: MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
What is the function of this protein?
Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
What are the official names of this protein?
Telomere-binding protein cav, Anonymous fast evolving 1G5, HP1/ORC-associated protein, HOAP p55, Protein caravaggio.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Note=Enriched at interphase, polytene and mitotic chromosome telomeres. Localized predominantly at telomeres and diffusely throughout regions of pericentric heterochromatin.
Protein: RR4_AETGR
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNTLFRLGMALTIPQARQLVNHGHILVNGRIVDIPSYRCKPRDIITVKDEQNSRTLVQNLLDSSAPEELPKHLTLHTFQYEGLVNQIIDRKCVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVC_HELPH
Sequence: MALPVYYDKDIDLGVIQSLQVGIIGYGAQGEAQALNLRDSKVKVRIGLYQGSLSVSKAKKEGFEVLGVKELVQQSDVIMALLPDELHKEVLEKEVIPFLKEGQIVGFAHGFSVHFNQVVLPKGVGAILVAPKGPGSALREEYLKNRGLYHLIAIEQESSKNNAKAVALSYAKAMGGGRMGVLKTSFKEECESDLFGEQAVLCGGLEAIVRMGFETLIKAGYPEELAYFECVHEVKLVADLLHYKGVEGLRKHISNTAEFGAIKAREPMGNLLEKRMQKILKKIQNGSFAKDFLLEKSLNYPRLNTERKALKETKIEQIGEILRAPFNHKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: BGAL_XANMN
Sequence: MLRTTLAPLVLALALALPAAAATPESWPTFGTQGTQFVRDGKPYQLLSGAIHFQRIPRAYWKDRLQKARALGLNTVETYVFWNLVEPQQGQFDFSGNNDVAAFVKEAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYLDALAKQVQPLLNHNGGPIIAVQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPGEAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLYMFIGGTSFGFMNGANFQNNPSDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGVQPPALPAPITTTTLPATPLRESASLWDNLPTPIAIDTPQPMEQFGQDYGYILYRTTITGPRKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLEVEIPAGQHTLDVLVENSGRINYGTRMADGRAGLVDPVLLDSQQLTGWQAFPLPMRTPDSIRGWTGKAVQGPAFHRGTLRIGTPTDTYLDMRAFGKGFAWANGVNLGRHWNIGPQTALYLRPSSARVTTRWWSSTWTMLHPSVRG
What is the function of this protein?
Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages.
What are the official names of this protein?
Beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
Protein: AIM39_CANGA
Sequence: MTYISRTMLWQRYLGTRISSTILPVAVRRIHYGGGRLQDPRYVFSKPPTNDPNQSKEGRDGKHFFTPSVNDGTENSTLHNNSRLSESEMSSIANAIAEQKRKRLKRSIITIFSAFVTAVLGYTIGYKVWYLKEQSFIPLYPCSRVRKLSTRDLRRVSVKKIEDISEVRVLERLSQHKMIQEEYGVPLRDSNGKAPHVSDFSVWCEDQDPCVTGLVFEPDSNRQSSHSWYRIPYVFKWRITHRPISISSFIDDVLNWINVSTSDLFEVISPEKVYGSFKYEYPIQGDNHSLHICFLGEMKLDENTTVIYKGKYHVDVKLERIDLLRTENKKLVRYILFKEEDEK
What are the official names of this protein?
Altered inheritance of mitochondria protein 39, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM39 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: TRUD_AERHH
Sequence: MLEQLAYLHGAPTARGILKAQAADFVVNEDLGFEPCGEGEHIFVRVRKTGENTAWVAGLLADAAGVNRSAVTWAGLKDRHAVTEQWFGIHLPGKAEPDLSVIESDSIQILQVKRHNKKLRVGYLKGNHFILRLTGLEQADGLESRLQAIAEQGVPNYYGEQRFGRGGNNLEAAKAMFAGKRIKDRNKRSLYLSAARSMLFNAIVSARIEQGLAHQLLAGDCVMLKGSHSIFSEEGVTPELAARLASGDVQLTAPQWGRGRLASQGAAAEFEQSVLAPYHDWCDGLEKAGLDQDRRPLLLKPQAMSWQLEGTVLILSFFLPAGAFATSVVRELMQAEEADHGFRNQSDENSGQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ADH1_DROMN
Sequence: MAIANKNIIFVAGLGGIGLDTSREIVKSGPKNLVILDRIDNPTAIAELKAINPKVTVTFYPYDVTVPVAETIKLLKTIFAQLKTVDLLINGAGILDDHQIERTIAVNFTGTVNTTTAIMEFWDKRKGGPGGVVANICSVTGFNAIYQVPVYSASKAAALSFTNSLARLAPITGVTAYSINPGITRTPLVHKFNSWLDVEPRVGELLLEHPTQTTLECAQNFVKAIEANKNGAIWQLDLGQLIAVEWTKHWDSHI
What are the official names of this protein?
Alcohol dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MASZ_BORPD
Sequence: MTERIQQDGLQVAAVLHRFIQDEALPAGGIDAPRFWAGFAALVRDLAPRNRALLAERDRLQRELDTWHRAHPGPVRDLRAYRAFLEQIGYLQPVPGTVRVETANVDAEIAEQAGPQLVVPMSNARYALNAANARWGSLYDALYGTDAIPPTPGDTGRGYHPQRGQAVIARARAFLDEAVPLAQGSHADATGYSVDNGQLRVALAQGSTGLAQPEQFAGYQGDAQAPQAILLKHHGLHIEIQIDRAHSIGATDAAGIKDVVVEAALTTIMDCEDSVAAVDAEDKVQVYRNWLGLMKGDLAEQVTKGGQTFTRRLNADRVYHAPGGGTLTLHGRSLMFVRNVGHLMTNPAVLDADGNEIPEGILDAVVTTLAALPDRASRRNSRAGSIYIVKPKMHGPAEAAFANELFDRVEDLLGLPRHTVKMGIMDEERRTSVNLKACIQAAAGRVAFINTGFLDRTGDEMHSSMEAGPMMRKGDMKSSAWIAAYERSNVLVGLDCGLRGRAQIGKGMWAMPDLMAAMLEQKIGHPKAGANTAWVPSPTAATLHALHYHQVDVPAVQQQLESTRLASVQDELLDGLLTVPVGNPADWSPDDIRHELENNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISSQHIANWMRHGIATREQVRDTFERMAAVVDRQNAGDPLYQPMAGHFDTSIAFQAACALVFEGLAQPNGYTEPLLHQYRLAFKARHNKG
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_BACC3
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGTKILQKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP65B_DANRE
Sequence: MVSRLEHPAGGYKKVFESCEELAEPIPAHVSGKIPAWLSGSLLRMGPGLFEIGDEPFNHLFDGQALIHKFDLKDGRVTYHRKFIRTDAYVRAMTEKRVVITELGTAAYPDPCKNIFSRFFTYFQGTEVTDNCSVNIYPIGEDFYACTETNFITKVNPDTLETIKKVDLCNYLSVNGLTAHPHIEADGTVYNIGNCFGKNMSLAYNIVKIPPLQEEKSDPLAMSKVLVQFPSSERFKPSYVHSFGMTENHFVFVETPVKINLLKFLTSWSIRGSNYMDCFESNDRMGTWFHLAAKNPGKYIDHKFRTSAFNIFHHINCFEDQGFIVVDLCTWKGHEFVYNYLYLANLRQNWEEVKKAALRAPQPEVRRYVLPLDIHREEQGKNLVSLPYTTATAVMCSDGTVWLEPEVLFSGPRQAFEFPQINYSKFNGKDYTFAYGLGLNHFVPDRICKLNVKSKETWIWQEPDAYPSEPLFVQSPDAEDEDDGVLLSIVVKPGVSQRPAFLLILKATDLTEIARAEVDVLIPLTLHGIYKP
What is the function of this protein?
Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid.  Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity).
What are the official names of this protein?
All-trans-retinyl ester 13-cis isomerohydrolase, 13cIMH, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein homolog B, RPE56b.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
Protein: URE2_RHIEC
Sequence: MIPGEIIAASGDIELNAGAPTVTLEVSNTGDRPVQVGSHYHFAETNAGLSFDRAAAHGKRLDIPSGTAVRFEPGQTRSVTLIPLSGRREVYGFRQLVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXI1B_XENLA
Sequence: MNPVQQPAQHRSPASLLHLPHPKRAQEAPDMGLYCDNFMFSQQNLHPSQRAPNFSIGGEFTPPANPYLWLGGPGMNNAPNYSPAPAPYIPSAFSAPQRHFMANSAAFGGADLGWMSAASQEELLKMVRPPYSYSALIAMAIQNASDKRLTLSQIYQYVAENFPFYKKSKAGWQNSIRHNLSLNDCFKKMPRDENDPGKGNYWTLDSNCEKMFDNGNFRRKRKPKSESNNAKIAKRDEDHLNPKGKESPPMITPSSSPEVLSPTGHSKSPSPPTVTYTPCLTNFIGSMTAVDSATMNRQSPLGLLNELSQRNITGLSSFISGSAVDQSSEHQDNSLFYNRSPYYTNQKQPHFLQQLHPQQPPLYQGRY
What is the function of this protein?
Transcription factor.  Essential for ventral specification of the early cephalic (head) ectoderm during gastrulation, playing a role in the 'non-neural' versus 'neural' cell fate choice.  Binds to DNA via the target sequence 5'-[AG]TAAA[CT]A-3', with 5'-ATAAACA-3' being the preferred binding site.
What are the official names of this protein?
Forkhead box protein I1-B, FoxI1-B, FoxI1b, xFoxI1b, Fork head domain-related protein 2', xFD-2', xFD2'.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCAI_HUMAN
Sequence: MVRGARQPQQPRSRLAPRLTGTVEKPPRKRRSRTEFALKEIMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLAETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGMQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDSEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTAYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFIFCSATMRMHKIFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNVFFENTIDDY
What is the function of this protein?
Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.  May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.
What are the official names of this protein?
Protein SCAI, Suppressor of cancer cell invasion protein.
What is the protein family that this protein belongs to?
Belongs to the SCAI family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus. Cytoplasm. Note=Nuclear localization is required for inhibition of MRTFA.
Protein: FLIE_DESHD
Sequence: MAFNPIAPVHPLMLQQNLNPIQENNPVEGSGPQTPAGAAKVGADFGQFLQEALQKVDNLQKEADVASLGLATGQIQDLHTAVIAMEKAGLSLSLTVDVRNRALDAYHEIMRMQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: GCSH_GLOC7
Sequence: MEHEYPDDLRYLDSHEYVRLDGEIATIGISAFAIEQLGDIVFLELPEVGEAVEVGESFGHIESVKAVEDLYPPVSGTVIERNEAMIDSPELIGDDPYGEGWLLKLRVVNPDNELDDTLTADEYRSQVEGEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RS7_EDWI9
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKTELEAFETALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RBGPR_RAT
Sequence: MACSIVQFCSFQDLQSARDFLFPQLREETPGALRRDPSKTSNWEDDSWGAWEETEPQEPEEEGNTSKTQKHSWLQECVLSLSPTSDLMVIAREQKAAFLVRKWKHSDKGKEEMQFAVGWSGSVSAEEGEYVTSALCIPLASQKRSSTGRPDWTCIVVGFTSGYVRFYTEGVLLLAQLLNEDRVLQLKCRTYEIPRHPGVTEQNEELSILYPAAIVTIDGFSLFQSLRACRNQVAKAAASGNENIQPPPLAYKKWGLQDIDTIIDHASIGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLSHVALAVASKLTSALFSAASGWLGWKSKHEEETVQKQKPKMEPATPLAVRFGLPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWKGYRDAQIGWIQIVEDLHERVPEKGDFSPFGNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGKHCRLLYPGYKIMGLNNVTSQSWQPQTYQICLVDPVSASVKAVNVPFHLALSDKKSERAKDLHLVKKLAALLRAKSPRPDSFEAEIKELILDIKYPATKKQALESILASDRVSFSCLRNVTQTSMDTLKNQELESVDEGLLQFCASKLKLLHLYESVSQLNTLDFHSDTPFSDNDLAVLLRLDDKELLKLRALLEKYKQENTKATVRFSEDADGVLPVKTFLEYLDYEKDALSIRKTSEEECVALGSFFFWKCLHGESSTEDMCHTLESAGLSPQQLLSLLLSVWLSKEKDILDKPQSVCCLHTMLSLLSKMKVAIDETWDSQSVSPWWQQMRMACIQSENNGAALLSAHVGHSVAAQMSSSATDKKFSQMVLDADAEALTDSWEALSLDTEYWKLLLRQLEDCLILQTLLHSRASPPAAKASSPQTEPLPRLSVKKLLEGGKGGIADSVAKWIFKQDLSPELLKCANREKDVENPDEPREGIARSPPEVSEVETDLGAVPDLLRLAYEQFPCSLELDVLHAHCCWEYVVQWNKDPEEARFLVRSIEHLRHILNPHVQNGISLMMWNTFLVKRFSAATYLMDKVGKSPKDRLCRRDVGMSDTALTSFLGSCLDLLQTSLEADISRDEVQVPVLDTEDAWLSVEGPTSIVELALEQKPIHYPLVEHHSILCSILYAAMSFSLKSVKPLALFDSKGKNAFFKDLTSIQLLPSGEMDPNFISVRQQFLLKVVSAAVQAQHSKDKDPSARAADTHGQDLNWTALAVDLAHHLQVSEDVIRRHYVGELYSYGADLLGEEAILQVQDKEVLASQLLVLTGQRLAHALFHTQTKEGMELLARLPPTLCTWLKAMNPQDLQNTGVPVAATAKLVHKVMELLPEKHGQYSLALHLIEAVEAMATL
What is the function of this protein?
Regulatory subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of Rab3gap1 and Rab3gap2, which has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43, and guanine nucleotide exchange factor (GEF) activity towards RAB18 (By similarity).  As part of the Rab3GAP complex, acts as a GAP for Rab3 proteins by converting active RAB3-GTP to the inactive form RAB3-GDP (By similarity).  Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones (By similarity).  The Rab3GAP complex, acts as a GEF for RAB18 by promoting the conversion of inactive RAB18-GDP to the active form RAB18-GTP (By similarity).  Required for recruiting and activating RAB18 at the endoplasmic reticulum (ER) membrane where it maintains proper ER structure (By similarity).  Required for normal eye and brain development (By similarity).  May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters (By similarity).
What are the official names of this protein?
Rab3 GTPase-activating protein non-catalytic subunit, Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the Rab3-GAP regulatory subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.