PharMolix/UniProtQA huggingface dataset:
Protein: ENDS2_STRP9
Sequence: MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQTGKTDQQVGAKLVQEIREGKRGPLYAGYFRTWHDRASTGIDGKQQHPENTMAEVPKEVDILFVFHDHTASDSPFWSELKDSYVHKLHQQGTALVQTIGVNELNGRTGLSKDYPDTPEGNKALAAAIVKAFVTDRGVDGLDIDIEHEFTNKRTPEEDARALNVFKEIAQLIGKNGSDKSKLLIMDTTLSVENNPIFKGIAEDLDYLLRQYYGSQGGEAEVDTINSDWNQYQNYIDASQFMIGFSFFEESASKGNLWFDVNEYDPNNPEKGKDIEGTRAKKYAEWQPSTGGLKAGIFSYAIDRDGVAHVPSTYKNRTSTNLQRHEVDNISHTDYTVSRKLKTLMTEDKRYDVIDQKDIPDPALREQIIQQVGQYKGDLERYNKTLVLTGDKIQNLKGLEKLSKLQKLELRQLSNVKEITPELLPESMKKDAELVMVGMTGLEKLNLSGLNRQTLDGIDVNSITHLTSFDISHNSLDLSEKSEDRKLLMTLMEQVSNHQKITVKNTAFENQKPKGYYPQTYDTKEGHYDVDNAEHDILTDFVFGTVTKRNTFIGDEEAFAIYKEGAVDGRQYVSKDYTYEAFRKDYKGYKVHLTASNLGETVTSKVTATTDETYLVDVSDGEKVVHHMKLNIGSGAIMMENLAKGAKVIGTSGDFEQAKKIFDGEKSDRFFTWGQTNWIAFDLGEINLAKEWRLFNAETNTEIKTDSSLNVAKGRLQILKDTTIDLEKMDIKNRKEYLSNDENWTDVAQMDDAKAIFNSKLSNVLSRYWRFCVDGGASSYYPQYTELQILGQRLSNDVANTLKD
What is the function of this protein?
Endoglucosidase that acts as a host immune evasion factor by mediating hydrolysis of the N-linked glycan from the Fc region of host immunoglobulin-gamma (IgG) during infection (PubMed:23865566, PubMed:27288408, PubMed:26156869, PubMed:30937380).  Specifically catalyzes the hydrolysis of the beta-1,4 linkage between the first two N-acetylglucosamine residues of the complex-type N-linked glycan located on 'Asn-297' of the Fc region of IgG antibodies (IGHG1, IGHG2, IGHG3 or IGHG4), thereby preventing interaction between IgGs and Fc receptors and ability to activate the complement pathway (By similarity).  Also able to cleave biantennary and sialylated glycans of host alpha-1-acid glycoprotein (ORM1 or ORM2) (PubMed:23865566, PubMed:27288408).  Acts on N-linked glycans with or without core fucosylation (PubMed:26156869, PubMed:27288408, PubMed:30937380).  In contrast to EndoS, also able to process oligomannose- or hybrid-type glycans (PubMed:26156869, PubMed:30937380).  Specifically acts on IgGs; does not act on immunoglobulin alpha, beta, delta or mu (PubMed:26156869).
What are the official names of this protein?
Endo-beta-N-acetylglucosaminidase EndoS2, Endoglycosidase S2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: VP6A_BTV10
Sequence: MSAAILLAPGDVIKRSSEELKQRQIQINLVDWMESEGGKEDKTEPKEESKAEGSKDGEGTQSESGQKEEGGKETKDADVDRRIHTAVGSGSGTKGSGERANENANRGDGKVGGGGGDADAGVGATGTNGGRWVVLTEEIARAIESKYGTKIDVYRDEVPAQIIEVERSLQKELGISREGVAEQTERLRDLRRKEKNGTHAKAVERGGRKQRKKAHGDAQREGVEEEKTSEEPARIGITIEGVMSQKKLLSMIGGVERKMAPIGARESAVMLVSNSIKDVVRATAYFTAPTGDPHWKEVAREASKKKNILAYTSTGGDVKTEFLHLIDHL
What is the function of this protein?
Surrounds and interacts with the genomic dsRNA.  Possesses ss- and dsRNA-binding capacity.  Its hydrophilic nature and capability to bind ss- and dsRNA suggest that it interacts with BTV genomic RNA.
What are the official names of this protein?
Protein VP6-A, Minor inner core protein VP6-A.
What is the protein family that this protein belongs to?
Belongs to the reoviruses VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid.
Protein: RS19_ROSDO
Sequence: MSRSVWKGPFVDSYVLKKAEASRESGRNEVIKIWSRRSTILPQFVGLTFGVYNGRKHIPVNITEDMIGQKFGEYSPTRTYYGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PYRD_SALAR
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPTKPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLIAIKNKQNDLQAIHHKYVPVAVKIAPDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKSTEIIRRLSQELNGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARSC_YEREN
Sequence: MSNITIYHNPTCGTSRNTLEMIRNSGNEPTVIYYLETPPTHDELVKLIADMGITVRALLRKNVEPYEELGLAEGTFSDEQLIGFMLEHPILINRPIVVTPLGTRLCRPSEVVLDILPEPQQGAFTKEDGEKITDESGKRLK
What is the function of this protein?
Involved in resistance to arsenate.  Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase, Arsenical pump modifier.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.
Protein: RIMM_SODGM
Sequence: MVKMSKQLRIAAPVEPVVVGKMGSAYGIRGWLRVFSSTEEAESIFDYQPWFIKRAREWQPIGLESWKRHNQDLIIKVRDIEDREAATLLTNCEIVVDASQLPDLDSGEYYWKDLLGCQVVTVGGYQLGEVIDLMETGSNDVLVVKANLKDAFGIQERLIPFLDGKVIKNVDLAAHIIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_RSVT
Sequence: MALSRLLSTLKSKVLYDDLSEESQKRVDNKNRKSLALSKRPLNQGRVTIDQAATMLGLEPFSFSDVKVNKYDMFIAKQDYSVKAHRKATFNILVDPYWFHQPLTHYPFFRVETFAMVWIGIKGRASGITTLRIIDKSYVNPSDQVEVEVRYPISKNFAVLGSLANFLALEDKHNLQVSVSVDDSSVQNCVISRTLWFWGIERTDLPVSMKTNDTVMFEFEPLEDKAINHLSSFSNFTTNVVQKAVGGAFTSKSFPELDTEKEFGVVKQPKKIPITKKSKSEVSVIM
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.
What are the official names of this protein?
Movement protein, Non-structural protein 4, NS4, Protein pc4.
What is the protein family that this protein belongs to?
Belongs to the tenuiviruses pc4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: MIAB_XYLFM
Sequence: MTGTSNIPTHGKEHKDAPALLPLPAPNPHHTHAAHPGDPSHDRPPSRGKLFIKTHGCQMNEYDSAKMADVLTTTEALELTDNPEEADIILINTCSIREKAQEKVFSQLGRWRALKTNGRDVIIGVGGCVASQEGETIVKRAPYVDLVFGPQTLHRLPDMIRARREQNRPQIDISFPEIEKFDHLPTPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLTEIAHLATQGVREINLLGQNVNAYRGAMDPGPSNNTNPAAPPYADLGLLIRAIAQFESIGRIRFTTSHPLEFSDSLVEAYRDIPQLANHLHLPVQSGSDRILSAMKRGYTALEFKSKIRKLRAVRPDISISSDFIIGFPGESDTDFQKTMQLIEDIGFDQSFSFIYSRRPGTPASNLEDHTPDEIKRTRLEHLQKHINAYAADISKRMIGTVQTVLVEGPSKKNPNELTGKTENMRPVNFPGNPRLIGQFIDVHITEALTNSLRGRVHTN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_THUAA
Sequence: MADFDAVLKCWGPVEADYTTIGGLVLTRLFKEHPDTQKLFPKFAGIAQADLAGNAAISAHGATVLKKLGELLKAKGSHASILKPMANSHATKHKIPINNFKLISEVLVKVMQEKAGLDAGGQTALRNVMGIIIADLEANYKELGFTG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SMC_RHOBA
Sequence: MLKALELAGFKSFADRTRFDFPDGITVVVGPNGSGKSNIVDAMKWVLGSQSAKSLRGKDMSDVIFKGSQTRGPAGAAEATIIFDNTGGQMPVDAPEVHVTRRVYRSGEGEYLINQQAVRLKDVKALIRGTGIGIDAYSLIEQGKVDRMLQANAKDRRAIFEEAAGISRFKAKKVEAERRLERVQTNLTRLGDIVDEVATRLKTLKSQAGKAERYRQASDRLKELRTVVAWNDWLTLSTELNEATTQLEAAQRQHRKADTLRESLEEQRQAAEMQLQTIADAAREAEQSRSELSGEIARIGGRRESDQTTLVEQRRTLIGHYRRLRAMRTEAGSAIADLRKTIAALEVAEAELADVQQKKESIAAKRDVEQATVHRIESARDDLQRDHLAAVRRVAEHEANRGRVAQQMREAARALEEIARNSVTAEEGLKTALRDHDEVARNVSELEKRITDAQREVEIADAKVCETRRVLERRREEIGSLKIRLQGITERARVLDELQQKQEGVSGGVREVLRMSNAELKKDLVGIVADCFSVDRQVAPLIDAALGPRSQYVIVRGGSVSDAISRGDIKIGTRVGIIRLDELPNRRPGDKIRLDGLAGVIGRADKMIDCEVELEPLVRHLLGNTWLVDTLATAIGLRKLSSAGLRFVTASGDLLDNDGSSVVGPPGGETGLVSRRSELAAAKSEMQHYSYQIAEAEKEVGRLTGVVDSEAAELGRHEQAMRKWITEHAAAEAKLHHVTERLSARQATVDELKRSSASHTELLATAKQQDGELAVSIQKGKQEIETLEAQRTEVDVQLTAASEQLREVQSEAMSISVEAARSEQRVESLTIAADVARRDQSQREAANQEVRDAMTRTRERITEIETRILEADNRLAELMIAMESADAKLQVLAAEANQEREATRRVQTESQAAIKAVAKATEAVATISSARDAAALKQSTLADRIAEDYQIDLRNDEPPEELAEIEDRSSVDEEISRLRGQVQNVGSVNMEALEELNELQVRYDELHGQYQDLTAAKDSLQRVIARINADSRRLFLDTLEAIRINFQKLYRKSFGGGHADLILEESDDPLEAGVEIVATPPGKPSFSNSLLSGGEKALTAVALLMSIFQYRPSPFCVLDEVDAPFDEANIGRFVTVLTEFLDQSKFIVVTHSKKTMTAATTLYGVTMQESGVSKQVSIRFEDVSEDGQINAA
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_RICPU
Sequence: MLYEKFEYNINNLIGNFGLSKMSIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIHIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTSVGEEALLRGPVKLTVSSRGLTTVKTIKSTNNFSIFNWIPWSSHGMTEVKLIHATMPREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKRIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STACT
Sequence: MIKIPRGTQDILPDQSRKWRYIEAKLDELMELYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIENKMQGDPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAQDPSIDAEILAMVMHIYQSFGLKHLKLVINSVGDFDSRKEYNKALIEHFEPVIDTFCNDCQARLYTNPMRILDCKVDRDKEAVKTAPRITDYLNEESKEYFNQVKQYLDDLNIPYVEDPNLVRGLDYYTHTAFELMIDSPDYDGAITTLCGGGRYNGLLELLDGPKQTGIGFALSIERLLLALEEEGIEIEEDEHLDLFIVTMGEKADRYAVNLLNDLRHHGIKADKDYLKRKIKGQMKQANRVGAEYTIVIGEQELEDGNIDIKHMDSGETDSIHLADLVSYFENKKEKQGEK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STRMT
Sequence: MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQGVRTLNGDLVAPSVKAGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_LEPIN
Sequence: MRKTIIAGNWKMNLSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGSSVIVGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLKNEFTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVATPSQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGASQKISSFAELF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_ANOFW
Sequence: MMLPPKYDHRAVEANRYEWWLKGKFFEATSDETKKPFTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRNEGKTRYDLGREKFVEETWKWKEEYAGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYKKGLIYRGEYIINWDPVTKTALSDIEVVYKDVQGALYHMRYPLADGSGYIEVATTRPETMLGDTAVAVHPEDERYKHLIGKTVILPIVGREIPIIGDEYVDMSFGSGAVKITPAHDPNDFEIGNRHHLPRILVMNEDGTMNDNALQYKGLDRFECRKQIVKDLQEQGVLFKIEEHMHSVGHSERSGAVVEPYLSTQWFVKMKPLAEAAIEQQKTEGKVNFVPERFEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGEVYVDHEPPADIENWEQDQDVLDTWFSSALWPFSTMGWPDKTSADYNRYYPTDVLVTGYDIIFFWVSRMIFQALEFTGKRPFKDVLIHGLVRDAQGRKMSKSLGNGVDPMDVIDQYGADSLRYFLATGSSPGQDLRFSTEKVEATWNFVNKIWNASRFALMNMEGFTYEDIDLHGEKSVADHWILTRLNETIETVTKLADKYEFGEVGRVLYNFIWDDLCDWYIEMAKLPLYGDDEQAKKTTRSVLAYVLDQTMRLLHPFMPFVTEEIWQQLPHEGESITVASWPQVRPELSNHEAAETMRLLVDIIRAVRNIRAEVNTPLSKPITLYIKAKDEHVKATLETNRAYIERFCNPSELVIDTTIPTVEKAMTAVVTGAELSLPLEGLINIEEEVKRLEKELQKLDQEVERVQKKLSNEGFLAKAPAHVVEEERKKERDYIEKREAVRARLAQLKQ
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF32_MACFA
Sequence: MLKNKGHSSKKDNLAVNAVALQDHILRDLQLRNLSVADHSKTQVQKKENKSLKRDTKAIIDTGLKKTMQCPKLEDSEKEYVLDPKPPPLTLAQKLGLIGPPPPQLSSDEWEKVKQRSLLQGDSVQPCPICKEEFELRPQVLLSCSHVFHRACLQAFEKFTNKKTCPLCRKNQYQTRVIHGGARLFRIKCVTRIQAYWRGYVVRKWYRNLRETVPPTDAKLRKKFFEKKFTEISHRILCSYNTNIEELFAEIDRCLAINRSVLQQFEEKYGHEITEEEWEKIQVQALRRETHECSICLAPLSPAGGQRVGAGQRSRETALLSCSHVFHHACLLALEEFSVGDRPPFHACPLCRSCYQKKILES
What is the function of this protein?
May play a role in sperm formation.
What are the official names of this protein?
RING finger protein 32.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_SHIBS
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_STRSY
Sequence: MKLNNLPSEFQEALPILEKIKAAGFEAYFVGGSVRDAILGRPIHDVDIATSSYPQETKQIFSRTIDVGIEHGTVLVLEGKKEYEITTFRTEEEYVDFRRPSQVSFVRSLEEDLKRRDFTVNAFALDEEAQIVDLFDGMTDLENRTLRAVGIPAERFNEDALRIMRGFRFAATLDFEIEPTTFEAMVQTAPLLEKISVERSFIEFDKLLMADFWRKGLRAMIDSKAYNFLPDLAGKSDELEAMLTSLTEEFRFSTSEQAWALLFVCLGIDNIKSFLKKWKTSNDFQRSVVKLVEIYQLRQAGPVTKQICFKYGKEFLYLVEELHQAQGFVTDFAAIDKIDQALTIHDKHEIVVNGGHLMKAFDLKPGPVLGELLKEVEFQIVEGQLENEEQAIMTFVKGILENE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: CBPA_ECOUT
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGTKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RHG19_CHICK
Sequence: MAAGAPAAGARRGGSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLTLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDSTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19.
Protein: RFCS_NANEQ
Sequence: MEIWTEKYRPKRIDDIINQEEIKKALKSFVEKKNMPHLLFAGPPGTGKTTAALALAHELYGDAWRENFLELNASDERGIDVIRHKVKEFARAKPIGDVPFKIVFLDEADALTRDAQQALRRIMEKYSQSTRFILSCNYFSKIIEPIQSRVTVFKFKPLEKEAFRELINRIVKGEGLILENEDEIINALYDIAEGDLRKAINILQAAAMMSKTITVDRLYEIASIAKPKEIDEVLNKAMQGNFLEARSMLIDLMLKYGMSGEDVIKAIQKRVWSLPISDREKLMILDKIGDIEFRIVEGADDLVQLDALLAWLGLGKYKNFTS
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: T185A_MOUSE
Sequence: MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD
What are the official names of this protein?
Transmembrane protein 185A, Erythropoietin-induced EST 3, Protein FAM11A.
What is the protein family that this protein belongs to?
Belongs to the TMEM185 family.
What are the subcellular locations of this protein?
Cell projection, dendrite. Membrane; Multi-pass membrane protein.
Protein: NUON_CYTH3
Sequence: MNAIILISVLGILSMMSEFIGLKKLIYPIILISLIGILGYNACTFWNNPETHYGMLVHNNYSVAFGSLLITITLFWFILFRSSYSSGEFNQGDHYALILFSTVGGLVLVSFSNMSMLFLGVEILSIPLYILAGSRKKDLHSVESSIKYFILGSFATGIMLLGIALIYGATGSFDFATIEKTASADPLFFIGITLLSIAFAFKVSAVPFHFWVPDVYSGAPTFITAFMSTFVKVAAFGAFYLMLDSIFESVPTYLSHTLIGLSALTIVVGNIAASYQDNVKRMLAFSGVSQAGYMLMVFPILTISAKTSLFVYLAGYAIANLIAIYIVQVVEKSKGDARVENFSGLGKSNPFLAFVLSLSLISLAGIPPAAGFFGKFYLFTEVIHAGNIYLVLIAILGSLISVYYYFKTIIAMYSGEEVSTLTNPAFGFTSVILAIMSALVVLIGLFPDILLQIGMNI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEC13_KLULA
Sequence: MVTINNAHSELIHDAVLDYYGKRLATCSSDHTVKIFEVEGETHKLVDTLQGHEGPVWQVDWAHPKFGVILASCSYDGKVLIWKEVNGRWSQIAAHEVHSASVNSIQWAPHEYGPLLLAASSDGKVSVVEFKENGTTSPIIIDAHSIGANTACWAPATLQQQSNQGTSGSASPQQVRRFVTGGADNLVKIWKYNSDAATYLLEHTLEGHSDWVRDVAWSPTVLSRSYLASVSQDRTCIIWTQDSKEDTWKKTLLKEDKFPDVLWRASWSLSGNILALSCGDNTVTLWKENLEGKWEPAGQVTE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: FENR_GLUDA
Sequence: MTDAPTLTTDVAIIGAGPAGLFAAFECGMLKLDSLLIDALDCVGGQCAALYPEKPIYDIPGHPAIAGAALIEGLEQQIAPFDVPRLLGRRVERLSGHRGAFTLGTDRGETIHARAVIIAAGAGAFGPNRPPLAGLDGFEATGAVQYYVRRRADFAGTRIVIAGGGDSAIDWALALKDEAEKIWLVHRRDRFRAAPESLRQLDEAVAAGRIEKIVPYQLHGLRGTDGALEGVEVATLDGDTRILPADRLLPFFGLSTDLGPIAHWGMDSIRSTIPVVPSSCETTLPGVFAVGDVAAYPGKLKLILQGFSEGAMAAHAIHPIVRPDTALHFEYSTSKGVPDRI
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.