PharMolix/UniProtQA huggingface dataset:
Protein: BIOD_BACAN
Sequence: MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKALQSGHVASNPEGDAARLKVLSGVPIKEDEICPYSIEEPLAPRLAMKRAGRAVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKEEVLESAKEYIMISKLEEFIRNESTVAHTSSN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1489_METJA
Sequence: MISSYGDVDMELRDEDLILEEVRDYLTAYLRNIHQEDIILDNERVVVDLNQLYNYGLMEFVEFLINNPQKGIDFIKECYNDAYYTLRNEYPTNVIIAVKNLPKIFKTTRKGKIFTIEDIRSKTLGKLVEFEGIIVMASKIRPMLKKAYYICPKCGREVVREIDILNTDSEKAVCECGAELNLIEHKSIYTDFQEIKVQQPLDLMENPEEPPKYITVFLENSPGIYAGRVKITGIPIKVKKSKKLPIYDIHVKALHCEVLDGEVKIKLTNSDIENIKKIAKRKDVVNILADRLIPEIKGHSAIKKAVLLQQIKGVKKPGKRADIHILLITDPGIGKTVILRKIAEIPGNLYGSVTTATGVGLTAAVVREKTEIGEDTWVIKPGLLVKAHKGTACIDELTVNKELQSYVLEAMESQTIHISKGGINAKLPAECAILAACNPRWGRFNPEVSVAEQINIPAPLLSRFDLIFPIRDVSDKDKDKDIAEYIVDLHRAYLDEKINREMGLDYLEVDGVKIDKEFIIKYIYYARQKKPIISEKAKELFVNYYVEMRKKHQITARQLEAAIRIAEAHAKAKLKDVVDEEDAKEAINIITECLKEIAYDPETGIFDVDKILGVSKKERDKLTTVYEIIKELSEKSELVEHEDIAEEAKKKGIKEDELENIIKKLIKYGDIDEPKPGRYRLL
What are the official names of this protein?
Uncharacterized MCM-type protein MJ1489.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
Protein: HIS6_METLZ
Sequence: MGLTRRIIPCLDLKAGRVVKGVNFEGLRDAGDPVELASRYNEQGADEVVFLDIAASKDNRDTMIDVIGRAADELFLPLTVGGGIRTVKDIQDILRAGADKVSLNTSAVKTPDVINEGSHLFGNQCIVLAEDVRRNYEMRDGVTPIHLADGRVCWYEVVIYGGSQRTGIDAVSWAQEGVKRGAGEILLTSMETDGVKTGFDLEITAAISENVDVPVIASGGVGTLEHFYDGFVKGKADACLAASVFHYGEMTIRSVKEYLASRGVLVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H1O_CHITH
Sequence: MSDPAPEIEAPVEAAPVASPPKGKKEKAPKAPKSPKAEKPKSDKPKKPKVAPTHPPVSEMVVNAVTTLKERGGSSLIAIKKFVAAQYKVDVEKLVPFIKKFLKSSVAKGTLLQAKGKGASGSFKLPPAAKKVEKKPKKVPSTPKPKTTKPKRVTGEKKVVKKPAAKKPEAKKATKAAKPATKKVVAKPASKKAAAPKPKAAKPAAKKPEAKKATKAAAKKPVAKPVAKKPAAKPAKKPAAKKAK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1, orphon.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GMHA_KLEP3
Sequence: MYQDLIRNELNEAAETLANFLQDEANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYEYVFSRYVESVGRAGDVLLGISTSGNSGNVIKAIEAARAQGMKVITLTGKDGGKMAGSADVEIRVPHFGYADRIQEIHIKVIHILIMLIEKEMVKG
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISW2_ORYSJ
Sequence: MAKPVKYDEEEEEVSSSGEEEEEQSDGAGSGSGEEEDEEEEEAPAAAAGEAAGGEEEEVDEEEIEAVTTGAGADEEEEESGAAAAAPGEGDEESQSTEDDEAVVGEDDDADEAEGGAVVGKREKARLKEMQKLKKQKIQEILDTQNAAVDADMNNKGKGRLKYLLQQTEIFAHFAKGNQSKEKKPRGRGRHASKMTEEEEDEEYLKEEEDALAGSGGTRLLSQPSCIKGKMRDYQLAGLNWLIRLYENGINGILADEMGLGKTLQTISLLGYLHEFRGITGPHMVVAPKSTLGNWIKEIQRFCPILRAVKFLGNPEERNHIRENLLQPGKFDVCVTSFEMAIKEKTTLKRFSWRYIIIDEAHRIKNENSLLSKTMRIYNTNYRLLITGTPLQNNLHELWSLLNFLLPEIFSSAETFDEWFQISGENDQQEVVQQLHKVLRPFLLRRLKSDVEKGLPPKKETILKVGMSQMQKQYYRALLQKDLEVINAGGERKRLLNIAMQLRKCCNHPYLFQGAEPGPPYTTGEHLVENAGKMVLLDKLLPKLKDRDSRVLIFSQMTRLLDILEDYLMYRGYQYCRIDGNTGGEDRDASIEAFNKPGSEKFVFLLSTRAGGLGINLATADVVVLYDSDWNPQADLQAQDRAHRIGQKKEVQVFRFCTEYTIEEKVIERAYKKLALDALVIQQGRLAEQKTVNKDDLLQMVRFGAEMVFSSKDSTITDEDIDRIIAKGEETTAELDAKMKKFTEDAIKFKMDDTAELYDFDDDKEENKLDFKKLVSDNWIEPPRRERKRNYSESEYFKQALRQGAPAKPREPRIPRMPHLHDFQFFNNQRLNELYEKEVRYLMQANQKKDTIDGEDEDQLEPLTAEEQEEKEQLLEEGFATWTRRDFNTFIRACEKYGRNDIRSIAAEMEGKTEEEVQRYAKVFKERYKELSDYDRIIKNIERGEARISRKDEIMRAIGKKLDRYKNPWLELKIQYGQNKGKFYNEECDRFMLCMVHKLGYGNWDELKAAFRMSPLFRFDWFVKSRTTQELARRCDTLIRLVEKENQEYDEQERQARKDKRMAKNMTPTKRSALRVSEGETTPSNSFKRRRQSLMDDYVGSGRRKRG
What is the function of this protein?
Possesses intrinsic ATP-dependent nucleosome-remodeling activity.  Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin in vitro (By similarity).
What are the official names of this protein?
Probable chromatin-remodeling complex ATPase chain, ISW2-like, Sucrose nonfermenting protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THRC_BACSU
Sequence: MWKGLIHQYKEFLPVTDQTPALTLHEGNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEGNDTIMCASTGNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDGNFDDALKIVRSICEKSPIALVNSVNPYRIEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNITAYWKGFKEYHEKNGTGLPKMRGFEAEGAAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAEESNGKIDEVTDDEILHAYQLIARVEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAVLTGNGLKDPNTAVDISEIKPVTLPTDEDSILEYVKGAARV
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: ADSSP_MOUSE
Sequence: MAAANRGSKPRVRSIRFAAGHDAEGSQSHVHFDEKLHDSVVMVTQESDNSFLVKVGFLKILHRYEITFTLPPVRRLSKDIRETPVHSLHLKLLSVTPTSEGYSIKCEYSAHKEGVLKEEMLLACEGDIGTCVRVTVQARVMDRHHGTPMLLDGVKCVGAELEYDSEQSDWLGFD
What is the function of this protein?
Adipocyte-secreted protein (adipokine) that acts as a key regulator for white adipose tissue (WAT) thermogenesis and glucose homeostasis at least in part through activation of protein kinase A (PKA).
What are the official names of this protein?
Adipose-secreted signaling protein.
What is the protein family that this protein belongs to?
Belongs to the ADISSP family.
Protein: THI4_METMJ
Sequence: MTLNEVTISRAILEEQHRALIDHLEMDAAVIGGGPSGLACAALLGEKGVKCALIEKKLSIGGGMWGGGMMFPRIVVQEDARRLLDRFGIAYKAFEEGYYVAKSVEAVAKLTAAACDAGVEFFNLTTVEDVMIRGDGRIGGLVVNWTPVDMAGLHVDPLTMACTCTVDATGHDAMIARMVEKKGGALTVKGESFMWAERAESQILAHTKEVFPGLFVTGMAANAVAGECRMGPIFGGMLLSGERAAELVAERLGR
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: ATAD2_PONAB
Sequence: MLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDEDDDDDDDDDDDDDEDDEDEEDGEEDNQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPASPARPRYRLSSAGPRSPYCKRMNRRRHAIHSSDSTSSSSSEDEQHFERRRKRSRNRAINRYLPLNFRKDELKGIYKDRMKIGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDAIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYRGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEALQRVFPHAEFRTNKTLDSDISCPLLESDLAYSDDDVPSVYENGLSQKSSHKAKDNFNFLHLNRNACYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIPVLFGVSATSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFTTLLQNIPSFAPVLLLATSDKSHSALPEEVQELFIRDYGEIFNVQLPGKEERTKFFEDLILKQAAKPPISKKKAVLQALEVLPVAPPPEPRSLTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSTLVGDKRSDPEQNEKLKTPSTPVACSTPEMCVLRMTRARRSQVEQQQLISVEKALAILSQPTPSLVVDHERLKNLLKTVVKKSRNYNIFQLENLYAVISQCIYQHRKDYDKTSLIQKMEQEVENFSCSR
What is the function of this protein?
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1.  May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters.  May be required for histone hyperacetylation (By similarity).
What are the official names of this protein?
ATPase family AAA domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOCS3_CAEEL
Sequence: MNDDQWVAGISKKDAGRYSRQLLVDDFGVSGQKNLKNLNVLIVGAGGLGCPVATYLGAAGIGTIGIVDYDHISLDNLHRQVAYKEDQVGKSKAQALADNIKLQNSDLNVQVHNTSLDSSNAMQLFKNYEIVCDCTDNVATRYLINDVCVLLNIPLVSGSALRWDGQLSVYHYGSDCPCYRCLFPSPPDPNSVTNCNEGGVLGPIVGVIGSMQALEVMKIAAKVRTTLAGQLLLFDGREGKSRTIRLRKRDPKCEVCGDNPTITAPIDYVLFCGAGAHDKIENLKLLELSDRVNVTEYRNKRREQKPVLLDTRPSLEFEIAHLPEAINVTLKECRSLSAEDISNRLGLQNTEHSDVFVICHRGNDSQRAVLLLREKLVDIKFRDIIGGYEQWALKINDMFPLY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin related protein 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_GEOSL
Sequence: MLMPKRVKHRKQMKGRMKGDAQRGASLAFGEFGLQATECGWVDSRQIEAARIAMTRYIKRGGKIWIRLFPDKPLTSKPAETRMGKGKGSPDSWVCVVKPGKVLYEMEGVTEEIAREAFRLAAHKLPVGTKFISRKDGHES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: IF2_YERPP
Sequence: MTDVTVKSLAAEIQTPVDRLVQQFADAGIKKSDVDSVTQQEKEILLAHLNREHGSVPNKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTYVNTPEAEQAKAEEQAQREAEEQAQREAEATAQKIAEEKAKREAEEQAKREAAEKAKRQAAEKEKVTNQQTDEKTKPAQTDKARREAEAAELKRSVEEETRRKVEEDAKRVAEEARKMAAENEGKWPEPVAEQTESADYHVTTSQHARAAEDENDAKVEGDRRSRTRGGKATKQKKGNKLSESKADREEARAVGRKGKRKPSTLQQSFNKPVVAVNRDVVIGETVTVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDIGVEAAAEHRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAANVPVVVAVNKIDKPEADPDRVKTELSQYGIQPEEWGGESQFINVSAKAGIGIDELLNAILLQAEVLELKAVRTGMANGVVIESFLDKGRGPVATVLVQQGTLNKGDIVLCGFEYGRVRAMRDELGRDITSAGPSIPVEILGLSSVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVIKSDVQGSCEAICDSLEKLSTDEVKVRIVGSGVGGITETDATLAAASGAIILGFNVRADASARRVVETEGLDLRYYSVIYSLIDEVKQAMSGMLAPEYKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVIKRNNPIRVLRDNVVIYEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRA5
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAEKFIALGASRLGTSRIIKIVKNQKVEEGTY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_PROS9
Sequence: MHLSPQEKDKLLIFSAAQLAERRLNRGLKLNYPETVAFLSFQVLEGARDGKSVSQLMSEGTTWLSKKQVMDGISEMVDEVQVEAVFPDGTKLVTIHNPIN
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_VIBCM
Sequence: MSSAKELKKSVLAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIASLVIVVDQILKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSEPIPSFIDGIGNGLGYGFVLMTVGFFRELLGSGKLFGLEVLPLISNGGWYQPNGLMLLAPSAFFLIGFMIWAIRTFKPEQVEAKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YKVA_BACSU
Sequence: MKKKKAIMLGAAGGKAILKRKNRKKCIQHITTFFQMLRDWRNGDYPRSQVKTLLLLTAAILYIVMPLDIIPDVILGLGFIDDAAVLGLIWTLIKKELSQYEKWRLQ
What are the official names of this protein?
Uncharacterized membrane protein YkvA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_RHIEC
Sequence: MKFLDEAKVYIRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWVEAVNGLNTLIDFRYQQHFKATIGTHGMGRNRTGANGSDVTLKVPVGTQIFEEDRETMICDLTEEGQRYCLAHGGNGGFGNAHFKTSVNQAPDWANPGLPGEEKTIWLRLKLIADAGLVGLPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATVDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVLLHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKACGRTPFQISAVTGRGMTEVLRALRDIIVQENAEEKPAKAPKLRHRDMIVSEENNQGEDGADDQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_NEPOL
Sequence: MTTNTQYIYPIFTVRWLAVHALAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GCST_SALG2
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIIYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTDEQRHAVEGMKPFFGVQVGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: H2A_EUGGR
Sequence: MSTTTPPPAKGGKDKKGAKAGVKKGKTGGSGQSKKAGLTFPVGRTGSLLRAGRYAKRVGKGAPVYLAAVLEYLSAELLELAGNASRDNKKKRITPRFLTLAVRNDEELNKLLSGVTIASGGVLPNIQQVLLKKKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ILVD_CITBB
Sequence: MRSDTITQGLERTPHRALLKGTGLPQSEMGKPFIGIATSFTDLIPGHVGMRDLERFIEKGVHTGGGYSFFFGIPGVCDGISMGHKGMHYSLPTRELIADMVESVAEAHRLDGLVLLTNCDKITPGMLMAAARLDIPCIVVTAGPMMSGRGDAGRKYSFVTDTFEAMARYKAGVIDDAELARCEENACPGMGSCQGLFTANTMAILTETLGMSLPRCGTALAVSALKRRIAFASGERIVDLVRQNITPRSILTREAFENAIRVDLALGGSSNTVLHLLAIAHEAGVELPLETFDILAKETPQLASMNPAGEHFMEDLDVAGGVAGVLKQLGDKIHDCPTLMGLSTKEIAASLKGVDEEVIHPLSNPVKKEGGIAVLFGNICPKGAVVKQSGVSDKMMKFTGTARCFDSEDKAMAAMMGGVVKGGDVVVIRYEGPKGGPGMREMLAPTAALMGLGLGDSVALITDGRFSGGTRGPCIGHIAPEAAAGGPIGLIEDGDTIELDIPARSLKVMVSDEVLAERRARWVAPEPKIKKGWLARYAKVVTSAHTGAITTAE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TBP_SPOFR
Sequence: MDQMLPSPYNIPGIDTPLHQPEEDQQILPNAMQQQHQHQQQQQQHALAAMGSSPLVGFGASLMGTPQRSVHTYAPAASYATPQQMMQPQTPQNLMSPMITSGSLAGQQMLSQASPAPMTPMTPHSADPGIVPQLQNIVSTVNLNCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEDSRLAARKYARIIQKLGFTAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVREEIYEAFDNIYPILKSFKKQ
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TBP, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL6_HERAR
Sequence: MSRVGKMPIALPSGAEATITAEQITVKGPLGSLSQALNGLVQIENASGTLNFKPANDSREANAMSGTLRALVNNMVNGVTKGFEKKLMLVGVGFRAAAQGDKLNLSLGFSHPVVHAMPAGIKVETPTQTEILIKGIDRQSVGQVAAEVRAYRPPEPYKGKGVRYSDEVVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FUT1_SAISC
Sequence: MWPRSHRHLCLAFLLVCVLSAISFLIHFHQDSIRHGLGLSVLCPDRRLVTPPVAIFCLPGTPMSPNTSSPCPQHPASLSGTWTIYPDGRFGNQMGQYATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWQELRLHDWMSEEYADLGDPFLKLSGFPCSWTFFHHLREQIRSEFTLHDHLREEAQSVLRRLRLGRSGARPRTFVGVHVRRGDYLQVMPQRWKGVVANSAYLREAMDWFRARHEAPVFVVTSNGMEWCRENIDASKGDVMFAGDGQEASPWKDFALLAQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFKPEAAFLPEWVGINADLSPLWPLAEP
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens.  H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (By similarity).  Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 1, Alpha(1,2)FT 1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RIMP_DESHY
Sequence: MGESIMEQVEAIIAPVITEQGLELVDVEYVKEGAHWYLRIYIDKEGGVDIDDCTNVSHLVSEVLDKHDPIAQAYMLEVSSPGLERPLKKDEDFERFTGKLVRVLTKEAYQGYKEFTGYLVGLIEDDIVLEYEKEKMAIPRAIVDKANLTFEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.