PharMolix/UniProtQA huggingface dataset:
Protein: XYNB_PRERU
Sequence: MKAKYVFPSDYMADPAANVFDGKLYIYPSHDYDSGECFDDDGGHFQMKDYHVLCIDGDPMEQDAKDCGKQFGIEDIPWVEKQLWDNDCVEKDGKYYLIYSAKDYTGVFHLGVAVADKPEGPFVPEADPIRGSYSIDPCVFKDDDGEIYVYFGGIWGGQLQWYKDNKMLKAEHLPEGKEDPLPSRVARMTGDVKQFAEAPRAVIIVDETGKPLPADDPHRFFEASWMHKYNGKYYFSYSTGDTHLLCYAVGDNPYGPFTYQGVILEPVVGWTTHHSIVEYKGKWYLFHHDCVPSNDTTWLRSLKVAELEYDAEGHIKTVK
What is the function of this protein?
Exoxylanase capable of acting on certain xylans and xylooligosaccharides.
What are the official names of this protein?
Beta-xylosidase, 1,4-beta-D-xylan xylohydrolase, Exo-beta-(1,4)-xylanase, Xylan 1,4-beta-xylosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
Protein: SYA_PSEAE
Sequence: MKSAEIREAFLRFFEEKGHTRVASSSLIPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWEFLTGEKWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPYASDNFWAMGDTGPCGPCTEIFFDHGPEIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVMHPLPAPSVDTGMGLERVSAVLQHVHSNYEIDLFQNLLKASAEAIGCANDDAPSLKVVADHIRSCSFLIADGVLPSNEGRGYVLRRIIRRACRHGNKLGARGTFFHKIVAALVAEMGDAFPELKQQQAHIERVLKTEEEQFAKTLEQGLKILEQDLAELQGSVIPGNVVFKLYDTYGFPVDLTNDIARERELTIDEDGFEREMEAQRERARASSAFGMDYNSLVKVDGETRFLGYQGVSGAGQIVALFRDGQAVERLEEGEEGVVVLDQTPFYAESGGQVGDSGYLEAAGVRFDVRDTTKAGGAHLHHGVVARGNLSVGGAVKAEVDASVRQATALNHSATHLLHAALRQVLGDHVQQKGSLVDSQRLRFDFSHFEAIKAEQLKALEDIVNAEIRRNTEVETEETDIDTAKAKGAMALFGEKYGDQVRVLSMGGDFSVELCGGTHVSRTGDIGLFKITSEGGVAAGVRRIEAVTGAAALAYLNGAEEQLKEAASLVKGSRDNLLDKLGALLERNRSLEKELEQLKAKAASAAGDDLSAAAVEIKGAKVLAARLDGLDGKALLALVDQLKNKLGRAVILLGGELDGKVVLVAGVTQDLTGQLKAGELMKQAAAAVGGKGGGRPDMAQGGGTDAAKLDEALALAQRFVEQGL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_SHEON
Sequence: MTRFLFAIILGLLLTACQQETVEETEFVPHKLTELRVGTLYGPQIYMTSGQGNSGFDYDMAVLFAEYLDVPLKMVPYTNLAELYDALKKNEIDIIAAGMTETPARREHFRLGPPLYRVNQVLVYREGMPAPKDISDLKGKITVIADSSFVETLTQLQKRHPTLVWDQVTDKDNEELLTMIANKEIDYTIADSSSVQINRRYLPVLRSGLVLEEKLNVVWLLPPTHSDGLMSQLLAFWHQEKLAGTLDHLNEKYFGHVKRFDYIDTRAFLRAIETVLPRYRQHFETHAGDLDWRKLAATSYQESHWNPNARSPTGVRGMMMLTQPTAKEIGITNRLDAEESIRGGAAYLRDMINRLPESIPESQRMWFALASYNIGYAHVEDARKLAESMELNPNAWQDLKKVLPLLQKRKYYQKTRYGYARGSEAVHYVDSIRRYYDTLVWVDNQSKQQNSEEVAPSDLTAEETPVPAPGTLSPDKPK
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: FTSY_THEAQ
Sequence: MGFFDRLKAGLAKTRERLLKAIPWGGNLEEVLEELEMALLAADVGLSATEEILQEVRASGRKDLKEAVKEKLVGMLEPDERRATLRKLGFNPQKPKPVEPKGRVVLVVGVNGVGKTTTIAKLGRYYQNLGKKVMFCAGDTFRAAGGTQLSEWGKRLSIPVIQGPEGTDPAALAYDAVQAMKARGYDLLFVDTAGRLHTKHNLMEELKKVKRAIAKADPEEPKEVWLVLDAVTGQNGLEQAKKFHEAVGLTGVIVTKLDGTAKGGVLIPIVRTLKVPIKFVGVGEGPDDLQPFDPEAFVEALLED
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: RL5_MOUSE
Sequence: MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (By similarity).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (By similarity).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity).  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs (By similarity).  It also couples ribosome biogenesis to p53/TP53 activation (By similarity).  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53 (By similarity).
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Although RP5 is functional within the cytoplasm, the assembly of ribosomal subunits occurs in the nucleus. RPL5 nuclear import is mediated by IPO5/RanBP5, IPO7/RanBP7, KPNB1/importin-beta or TPNO1/Trn.
Protein: EFG_DEHMB
Sequence: MSDRKYPLERVRNIGIIAHIDAGKTTTTERILYLTKRTHKIGNIDEGTTVMDWMEQEKARGITITSAATSAYWNGHHLNIIDTPGHVDFTAEVERSLRVLDGGVVVFDGVAGVEAQSETVWRQASRYGVPRICFINKMDRTGANYERTLGMIAERLKAKYLPLQIPIGCAETFRGNCDLLDFKCYGMDNSPEEPVETFDLPAAEKERAVKFRNMMIERLAEEDDEVMEAYLAGEELPIEKLKAAIRRVCLANKAIPIFCGTSLRNKGVKRLLDAVCDYLPSPLDIPAMKGTDPKTGESIERHTSDTEPFSALAFKIVSDPFVGRLVYFRIYSGSISAGSGAYNSTRGERERIGRLIRMHANDREEIEYADAGEIVASLGLRNTFTGDTLCDQNAPILLENIKFPEPVINLAIEPKTRSDQDKMTEGLQKLAEEDPTFKVKFDDETGQTVIYGMGELHLDVLVSRLLSEFKVNAGVGKPRVAYREAITAHAKAQGKFVRQSGGRGQYGDVTIEIEPRERGAGYEFVDNVKGGAIPRNFLMAAESGIRDTLETGVYAGYPMVDVKVIATDGSYHDVDSNENAFKMAGSMAIKAAVAKAKPILLEPIMKLEAVTPEEYMGDVIGDLNSRRGQIISVEPSPETTVITGTVPLAESFGYTTDLRSVTKGRATFSMEFESYREMPGELATQVVEAAGKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_ALIB4
Sequence: MAVPKRRVSHTRSAKRRTHYKITLKKPVKDSDGSWKMPHMVNPNTGEYKN
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: UBIQ_RABIT
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
What is the function of this protein?
Ubiquitin Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Ubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYY_ANASK
Sequence: MQNLLEALVSRSLVHDQTPGLQARLAQGPITGYVGFDPTADSLHVGHLLAVMSLAWLQRCGGTPIIVVGGGTGMVGDPSGKRSERPVLSVEEIDRNVAAIRAQLERFVSFEGQNAARVRNNADWLRAIGLMEFLRDVGKHFTVNYMLAKDSVKGRMESGISFTEFSYQLIQAYDFWHLFRSEKCELQMGGSDQWGNITAGAELVSRKDGASVHGLTFPLLTTASGTKFGKTEGGAVWLDPARTSPYKFFQFWLNTDDRDVERLLKFFTFLSVEDIAALLAEQARDPGKRPAQRRLAEDVTARVHGPDVTRSVIEASRILFGGTDLRAASADVLDVLAGEIPSAAVTGDELAALTIADLLVKVGLAASKGEVRRGVAGRGFSLNGAVLESGDAKVAAGDLLAGGYALLQKGKRNYALVKVR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP2_ASFWA
Sequence: MEAFEISDFKEHAKKKSMWAGALNKVTISGLMGVFTEDEDLMALPIHRDHCPALLKIFDEIIVNATDHERACHSKTKKVTYIKISFNKGVFSCENDGPGIPIAKHEQASLIAKRDVYVPEVASCHFLAGTNINKAKDCIKGGTNGVGLKLAMVHSQWAILTTADGAQKYVQHINQRLDIIEPPTITPSREMFTRIELMPVYQELGYAEPLSETEQADLSAWIYLRACQCAAYVGKGTTIYYNEKPCRTGSVMALAKMYTLLSAPNGTIHTATIKADAKPYSLHPLQVAAVVSPKFKKFEHVSIINGVNCVKGEHVTFLKKTINEIVVKKFQQTIKDKNRKTTLRDSCSNIFIVIVGSIPGIEWTGQRKDELSIAENVFKTHYSIPSSFLTSMTKSIVDILLQSISKKDNHKQVDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSFDFCGMISLGGVIMNACKKVTNITTDSGETIMVRNEQLTNNKVLQGIVQVLGLDFNCHYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGFVKRLLTPLIRVYEKGKTVPVEFYYEQEFDAWAKKQTSLANHTVKYYKGLAAHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGVVPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRARRKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQYYPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAEDSWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDILALVRAYVDKNNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYYSYGTYVISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSSSETIEILVKLKPNSLNRIMEEFKCTEEQDSIENFLRLRNCLHSHLNFVKPKGGIIEFNTYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYINESAELNLSHYEDEKEASRILSEHGFPPLNQTLIISPEFASIEELNQKALQGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGASVWLEEIDAVEKAIIKGRNTQWKFH
What is the function of this protein?
Type II topoisomerase.  Processively relaxes supercoiled DNA.  Displays DNA-supercoiling activity only when associated with the viral histone-like protein.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Localizes to the cytoplasmic viral factories.
Protein: RR4_VITVI
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRAGSDLRNQSRSGKRSQYRIRLEEKQKLRFHYGLTERQLLNYVRIAGKAKGATGRVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITAGNEQKSRALIQNVFDSSSHEELPKHLTLHPFQFKGLVNQIIDSNWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1830_STRE4
Sequence: MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYINKEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG
What are the official names of this protein?
UPF0298 protein SEQ_1830.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALX_KLEPN
Sequence: MSNGIKRYISVMQLTLINKKHMHYAPHIAMLVTLLLIGQQLAKLSWRMILPAYSPAIEMNDATEI
What are the official names of this protein?
Protein MalX.
Protein: BETI_KLEP3
Sequence: MPKLGMQPIRRRQLIDATLDAINEVGMHDATIAQIARRAGVSTGIISHYFKDKNGLLEATMRDITSQLRDAVLNRLHALPDGSASQRLQAIVGGNFDETQISSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVYEFRRELPREQAQEAGYGLAALIDGLWLRAALSGKPLDKTLAQSLTSHFIRQHLPNP
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: LDLR_PIG
Sequence: FQCQDGKCISYKWICDGNTECKDGSDESLETCMSVTCKIGDFSCGGRVNRCIPESWRCDGQQDCENGSDEEGCSPKTCSQDEFRCQDGKCIAPKFVCDSDRDCLDGSDEASCPTPTCGPASFQCNSSTCIPELWACDGDPDCEDGSDEWPQHCRSHSSSLPERSNNPCSALEFHCHSGECIHSSWRCDGDTDCKDKSDEENCDVATCRPDEFQCSDGTCIHGSRQCDREYDCKDMSDEQGCVNATLCEGPNKFKCQSGECISLDKVCNSVRDCRDWSDEPLKECGTNECLDNKGGCSHICNDLKIGYECLCPEGFQLVDKHRCEDIDECQDPDACSQICVNLEGSYKCQCEEGFQLEPLTKACKAIGTIAYLFFTNRHEVRKMTLDRSEYTSLIPNLKNVVALDTEVASNRIYWSDLSQRKIYSTQIDRAPSFSSYDTIIGEDLQAPDGLAVDWIHSNIYWTDSILGTVSVADTKGVKRKTLFQEKGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDVYSLVTEDIQWPNGITLDLSGGRLYWVDSKLHSISSIDVNGGNRKTVLEDKTKLAHPFSLAIFEDKVFWTDIINEAIFSANRLTGSDIHLMAENLLSPEDIVLFHNLTQPRGVNWCERTALQNGGCQYLCLPAPQINPRSPKFTCACPDGMLLAKDMRSCLTETEPAGTTQGPSMVNSTAVGPKHTASSELTTAESVTMSQHALGDVAGRGVTEKPQSVGALYIVLPIALLILLFFGTFLLWKNWRLKSINSINFDNPVYQKTTEDEVHICRSQDGYTYPSRQMVSLED
What is the function of this protein?
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis.  In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
What are the official names of this protein?
Low-density lipoprotein receptor, LDL receptor.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Golgi apparatus. Early endosome. Late endosome. Lysosome. Note=Rapidly endocytosed upon ligand binding.
Protein: ICP34_HHV11
Sequence: MARRRRHRGPRRPRPPGPTGAVPTAQSQVTSTPNSEPAVRSAPAAAPPPPPAGGPPPSCSLLLRQWLHVPESASDDDDDDDWPDSPPPEPAPEARPTAAAPRPRPPPPGVGPGGGADPSHPPSRPFRLPPRLALRLRVTAEHLARLRLRRAGGEGAPEPPATPATPATPATPATPARVRFSPHVRVRHLVVWASAARLARRGSWARERADRARFRRRVAEAEAVIGPCLGPEARARALARGAGPANSV
What is the function of this protein?
Plays essential roles in viral nuclear egress to mediate capsid transit across the nuclear membrane and also in the inhibition of host immune response.  Facilitates nuclear egress cooperatively with host C1QBP and protein kinase C/PKC to induce lamin A/C phosphorylation and subsequent reorganization.  In turn, lamina disassembles and nuclear egress occurs (PubMed:27630226).  Recruits the serine/threonine protein phosphatase PPP1CA/PP1-alpha to dephosphorylate the translation initiation factor eIF-2A, thereby couteracting the host shutoff of protein synthesis involving double-stranded RNA-dependent protein kinase EIF2AK2/PKR.  In turn, controls host IRF3 activation and subsequently inhibits host interferon response (PubMed:28904192).  Controls the DNA sensing pathway by interacting with and inhibiting host STING/TMEM173 (PubMed:30045990).  Also down-modulates the host MHC class II proteins cell surface expression.  Acts as a neurovirulence factor that has a profound effect on the growth of the virus in central nervous system tissue, by interqcting with host BECN1 and thereby antagonizing the host autophagy response (PubMed:18005679).
What are the official names of this protein?
Neurovirulence factor ICP34.5, Infected cell protein 34.5, protein gamma(1)34.5.
What is the protein family that this protein belongs to?
Belongs to the PPP1R15 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host nucleus, host nucleolus. Virion. Note=At early times in infection, colocalizes with PCNA and replication proteins in the host cell nucleus, before accumulating in the host cytoplasm by 8 to 12 hours post-infection.
Protein: HSCA_ALIFM
Sequence: MLLQIAEPGQSAVPHQHKLAVGIDLGTTNSLVASVRSGEAKTLPDMKGNVILPSVVQYQEDKICVGMNAYQSAAMDPQNTIISVKRLMGRSLKDIQARYPELPYQFSESENGLPVIQTAQGEVNPIQVSSEILKSLSRRAQDTLGGELEGVVITVPAYFDDAQRAGTKDAATLAGLNVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSKGVFEVLATGGDSALGGDDFDHVLAQWIKEQAGITSSLSSQEQRELLTLATQTKVALSDSDNVKISFKDWSGEISVELFNSLIQPLIKKTLMACRRALKDADITSEEVMEVVMVGGSTRTPFVRTSVGDYFGQTPLTSIDPDQVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVAKAQEFTTFKDGQTGMMVHVVQGEREMVEDGRSLARFSLKGIPPMAAGAAHIRVTYQVDADGLLSVTAMEKSTGVQSHIQVKPSYGLSDNEVANMLKDSMTYAKEDMQARALAEQQVEADRVIEGLVVALNNDGDALLSKEEQAEILQAIEALITLRQGTDAQAIEDGIKKADEASQEFAARRMDASIRAALAGQSIDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS21_ECO27
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PTAS_MYCGE
Sequence: MSVIDIFKKRLQAVSKKPVIIFPEGWSASVLKAVEMLNESKLIQPAVIFHNRQEIPANFDKKITHYVIDEMDLTSYANFVYEKRKHKGMDLKEAQKFVRDPSSLAATLVALKVVDGEVCGKEYATKDTLRPALQLLATGNFVSSVFIMEKGEERLYFTDCAFAVYPNSQELATIAENTFNFAKSLNEDEIKMAFLSYSTLGSGKGEMVDKVVLATKLFLEKHPELHQSVCGELQFDAAFVEKVRLQKAPQLTWKNSANIYVFPNLDAGNIAYKIAQRLGGYDAIGPIVLGLSSPVNDLSRGASVSDIFNVGIITAAQAIK
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_NEIG1
Sequence: MLFSRIIAASAQRKLSVYLKKGGLVAYPTESCYGLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQLEQLQPLLQMPSENIQTMLRNEWPAPKTFLLLAKSGVLPALRGKRRSKLAVRVPDHTGARRLCQALGMPLVSTSCNRAGKRACRTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGETGKRLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL11B_OLEEU
Sequence: MSCIAVEAVLLGILLYIPIVLSDDRAPIPANSAQLNSWFDGIIQPVAVRKATMDPALVTAEGQAKVIKLKSDGSGDFKSINEAIKSIPDDNTKRVILSFSPGNYSEKVKIGMYKHYITFYGEDPNNMPILVFGGTAAEYGTVDSATLIVESNYFSAVNLKIVNSAPRPDGKRVGAQAAALRISGDKASFYNVKIYGFQDTLCDDKGKHFYKDCYIEGTVDFIFGSGKSIFLNTELHAVPGDQPAIITAQARKTESEDTGYYFVNCRVTGGGAFLGRSWMPAAKVVFAYTEMGDAIHPEGWILVKPEHESTVRFPEYNNKGPGANMEKRAKFVKRLSDAEAKQSISLGSIEASKWLLPPRVVGLP
What is the function of this protein?
Catalyzes the demethylesterification of homogalacturonan components of pectin.  May be involved in pollen tube development (By similarity).
What are the official names of this protein?
Pectinesterase 2, Pollen allergen Ole e 11.0102, Ole e 11-2.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIMT_SHEB2
Sequence: MTRVALTSAVNLAKKLHDAGIRNQAVLKAISHTPREMFLDNALAHKAYENTALPIGQGQTISQPYIVARMTELLLHKMPQRVLEVGTGSGYQAAILAQLVPQLCTIERIKGLQIQARQRLKRLDLHNVSFKYGDGWLGWANRSPFDAIMVTAAASTIPEALLSQLAEGGVLVLPVGEDTQQLMRITRTADRFSSETIETVKFVPLINGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_ECOBW
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.