PharMolix/UniProtQA huggingface dataset:
Protein: NUOH_PSEAB
Sequence: MSWLTPALVTIILTVVKAIVVLLAVVICGALLSWVERRLLGLWQDRYGPNRVGPFGAFQLGADMVKMFFKEDWTPPFADKMIFTLAPVIAMGALLVAFAIVPITPTWGVADLNIGILFFFAMAGLTVYAVLFAGWSSNNKFALLGSLRASAQTISYEVFLALSLMGIVAQVGSFNMRDIVQYQIDNVWFIIPQFFGFCTFIIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIVLVSALLATLFFGGWHGPFLDTLPWLSFFYFAAKTGFFIMLFILIRASLPRPRYDQVMAFSWKVCLPLTLINLLVTGALVLAAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_CLAM3
Sequence: MVESIARVRHIRVTPQKARRVVDMIRGKQAEEALAILKFAPQGASEPIYKLVASAMANARVKADASNSFLAEQDLYIAKAFVDEGTTLKRFQPRAQGRAFRINKRTSHITVVLATPDEADVATTTKKASK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RSMA_SERP5
Sequence: MNNKVHQGHFARKRFGQNFLTDQFVIDSIVSAIHPMPGEAVVEIGPGLGALTEPVGARMDRMTVIELDRDLAARLANHPQLKDKLTIHQQDAMTVNFAEMAEQAGQPLRVFGNLPYNISTPLMFHLFSYTQAIRDMHFMLQKEVVNRLVAGPNSKAYGRLTVMAQYYCNVIPVLEVPPTSFTPAPKVDSAVVRLVPHLVNPNPVGDVRMLSRITTQAFNQRRKTVRNSLGDLFTPEQLTELGIDPILRAENISVAQYCKLANWLSANPAPQQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_LEGPL
Sequence: MSSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQTLGEKTLAYSNNPLHPVTLQSTGKMIPLIGLLEEFGADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAGAIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFASEKRTGNRNRALAYLLKSRNNLGADVHETLDLYFALCSYEAMLDQMLYLPTLLANSGKDSDTGEQILSMETCKITLAIMATCGLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLSKAMNWHFALP
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: CBK1_EMENI
Sequence: MSEDQGQQGQRLSTARGSTCLKQTMTEPALSAGLGTDGPVGAAKDNIRVRIQSRRRSRLLSRLGRKIPTQGRFTVGWYFWFLLIYTSLAVEPVKSHETHSHSSDAEGTSHQDVSDRRNHPCHTPRPSSHSQADSFESVARGQQKEQSRTMREDAVSPVLLDVKRSQSTPVELAKLVSLKLSTSFGSRTVIRRSQPGVRQSVRAAQLQRMMLDRGNPKRERSSGSSTPSSKSSPVDSVSTAPTSVSPGSLAPSGSTNNDPASGFKHIDSQADLPERPLSPVRESPMVSPTIQTTEATAIVKVFLETHFHTLLSGLDARTQRRLELDQYIETFPLSPEEVVRVRKHWVTQERDYLRQYRVLKSRPQDKTSRAGTASLAGFEPLKILGRGSFGVVRLVREKRTDEQTQSGRVPLAPKTNHRQAMTGVKKDVFAMKVIRKSVMIRNCQEAHLRAERDFLVASAKSRWVVPLIASFQDQKHLYLVMDYMVGGDFLGLLIRHNILRESIARWYVAEMILCIEEAHRLRCIHRDVKPDNFLISESGHLKISDFGLAFDGHWAHDQWYFTYQRHSLLKRLGIQIDGDAEDQKLSHDANIQSLGTTREDGSMEDDWIHPPTNGLLHWRDKNQTRTMARSVVGTSQYMAPEVIRGHPYDGRCDWWSLGVILYECLYGFTPFASEDRHQTKLKIHRHLQTLYFPVHRPTDKLVSADAIDVINSLLQEKEFRLSSPKYKQNDAISSKPAKCSFYKPDSSNPSYQGHYVYPDDATDIKSHRFFRGINWEQIHRTSPPFIPMVRGWEDTRYFDDGEHPSDREDDSSDSELDGVQDKWHPLGGKGGLHKPDKPLKADVKPSSYPKGNDGAKDTAIASLKHKKRLKEAKRARDKILRDKRLRRTVLEMLRCLVVVAAT
What is the function of this protein?
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase cbk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
Protein: KPYK_STAAW
Sequence: MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: BIOB_POLNA
Sequence: MTSITTIPLSTLRSSLPARPDAAAAPQRWRVADIEALYALPFMDLLFRAQQVHRANFDANQVQLSTLLSIKTGGCAEDCGYCPQSSHFETEVKASKLMALDEVMAAAQAAKDQGATRFCMGAAWSRPKERDMERVTEMVREVRGLGLETCMTLGMLEAEQAQALKDAGLDYYNHNLDSSPEFYGSIISTRTYQDRLDTLENVRGAGINVCCGGIVGMGESRAQRAGLVAQLANLEPYPESVPINNLVAVEGTPLADTPPLDPFEFVRTIAVARITMPRTMVRLSAGREQMDEALQALCFMAGANSIFYGDRLLTTSNPQADKDRQLFARLGLKVQGERPAATVQG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TX32A_SCOMU
Sequence: MRIWSLTRILTFIVIFNFAEAGGECMKKCDSPDMIREIFTRCTMVKRDTQFSENSGHLIPKRSVVADNKCENSLRREIACGQCRDKVKTDGYFYECCTSDSTFKKCQDLLHK
What is the function of this protein?
Gating-modifier toxin that inhibits voltage-gated sodium channel with a preference for hNav1. 7/SCN9A (IC(50)=25. 4 nM) over hNav1. 1/SCN1A (IC(50)=4. 1 uM), hNav1. 2/SCN2A (IC(50)=813 nM), and hNav1. 6/SCN8A (IC(50)=15. 2 uM) (PubMed:24082113).  Is an effective analgesic in rodent pain models, since it is several-fold more effective than morphine in a rodent model of formalin-induced pain and is equipotent with morphine in its ability to reduce thermal and acid-induced pain (PubMed:24082113).  In addition, this peptide shows a high level of resistance to proteases and a high thermal stability that may be explained by its predominant composition of alpha-helices (PubMed:24082113).
What are the official names of this protein?
Mu-scoloptoxin(03)-Ssm2a, Mu-SLPTX(03)-Ssm2a, Mu-scoloptoxin-Ssm6a, Mu-SLPTX-Ssm6a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-03 family.
Protein: PSAC_AETGR
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PROB_ESCF3
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGSVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIAA_ECOLI
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: GMHA_BRASO
Sequence: MTDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAADAQHIAAEIVGRYKQERPAFAAIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLLAISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELCDELLVAPSDDTPLIQQIHLATAHGICETIEAALMQDAR
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICR_SALPK
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDVQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: LEU3_CHLCH
Sequence: MNYKIVSIPGDGIGTEVVAGAVAVLRQLEKKYGFTVEIEEHLFGGASYDVHGEMLTDATLEACKNCDAVLLGAVGGPKWENLPHEHKPEAALLKIRKELGLFANLRPAKVYDALVDASSLKADVVRGTDFVVFRELTGGIYFGQPRGYDENKGWNTMVYEKYEVERIARLAFEAARQRQGRVMSIDKANVLEVSQLWRNVVHAVHADYQDVELSDMYVDNAAMQIVRNPKQFDVIVTGNLFGDILSDISGMITGSLGMLPSASIGSKHALYEPIHGSAPDIAGQNKANPIATIASVAMMFEHSFKRTDIARDIEQAIEAALATGVRTADIAAAGDTAVSTTAMTEAIISQLK
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA_XENLA
Sequence: MESKAFNKPKVELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLQKFNHYMPAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPHFLANSKVDPIPWGQKEGDITPDEVVDLVNQGLRKGEKTFNIKARSILCCMRHMPNWSSEVIELCKKYQNDTVVAIDLAGDESLNCESYPGHRKAYEEAVKCGIHRTVHAGEVGPPSVVKEAVEVLKAERIGHGYHTTEDPNLYKELLENNMHFEVCPWSSYLTSACHPDFTKHPATQFRKDKANFSLNTDDPLIFGSTLDVDYSIAVQHMGFTEDEFKRVNINAAKSSFLPDNEKKELLYKLYEAYGMILSTGL
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.  Plays an important role in purine metabolism and in adenosine homeostasis.  Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events.  May act as a positive regulator of T-cell coactivation (By similarity).
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm. Lysosome.
Protein: ATPF_BACVZ
Sequence: MSQLPLELGLSFNGGDILFQLLAMLVLLALLKKFALGPLLNIMKQREDHIAGEITSAEERNKEAQKLIEEQRVLLKEAKQESQSLIENAKKLGEKQKEDIIQAARAESERLKEAARTEIVKEKEQAVSALREQVASLSVLIASKVIEKELDEQAQEQLIQDYLKEVGESR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL2_PARP8
Sequence: MAIVKVKPTSPGRRAMVKVVNKDLHKGKPYAPLLDTQSSTAGRNNNGHITTRHKGGGHKHHYRIVDFRRTKDGIPAKVERLEYDPNRSANIALVVYADGERRYIIAPKGVTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGTYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGKTAAGRDPVSPWGTPTKGYRTRSNKRTTSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NDUV1_MOUSE
Sequence: MLAARHFLGGLVPVRVSVRFSSGTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGALRRGDWYKTKEILLKGPDWILGEMKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSDYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVKGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEDRMQRFAQQHRAWQAAS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH-ubiquinone oxidoreductase 51 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CSRA_SHIDS
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: H1BP3_MOUSE
Sequence: MQSPAVLRTSRQVQNAHTGLDLSVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSCYPAASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTRAPGATGLATRDPSVLDDTASQPGDSDEAFDFFEQQDEVQPPTLGLSSKDVEKSLVGEEEEEEEEEEVLDPLGIMRSKKPKKRPEVAVRPKPAPRLTIFDEEVDPDAGLFSSDKKVSETRRPLETTQDSLKLFDDPDLGGAVSLGDPLLLPAASESRGPTSRPEHGDASKELFRVEEDLDLILNLGSEPKPKPQTKPKPLVPAKPALPRKPTLPASVGPSEPGSGPQKQQQIQAMDEMDILQYIRDHDTLAQDSPSLF
What is the function of this protein?
May be a modulator of IL-2 signaling.
What are the official names of this protein?
HCLS1-binding protein 3, HS1-binding protein 3, HSP1BP-3.
Protein: IBPA_SALCH
Sequence: MRNFDLSPLYRSAIGFDRLFNLLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIELERVIPEANKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIGD_SERS3
Sequence: MTTMIGQTRQAGSSSYEQAWQAEQAPCPGMEPDTLTVGVVVVTRNPTFFQTGLSVLNDIRDYVFNRVHIQSELPLKLSELASDPLYSEAREKAIHFLKNQSKALNIQVIQCASLAEATGKIIYTHALEQQPEFQMGMLFYDQTSLGNVDDSIEKIDRDLDAFYSAMQRGGIPAFYTTFSTVTFIRDVRSSFRYLPQQYREIVRSEDPAIFQTELLCLWMDFFEMNYTNRRVKPIGALALHNTLAEQLIQFFERTAASRWLVSYYTGSIISNLIGYLDRHAEAHGALVLRGPNEHAIACGAMANWQLYRMPFLGVVTSGMMDEFKGTLINLKETAAQGIIVAAENRNNQWYSFQGTQTPTEDMRDVLAAKRIPYVYIDDVDGIADGLAEVFRLYHQAQGPVVILATQNVLESTLSLEPVPGDLPPVSGLPAYDCPPISDSFEQAMALINEGPEKLVWQLGPVSDDEYALVHEIADAAGLALVDSLAHPGSAPKYYQGKRNPHYLGTLAIYGYSPRVYNFLHTNDKLNPMSDQSVFMIKSRVAQITTPFSDGRLERKVHLVQLTHDERHLSPYADLKLHMDCLTFLRAVKANLHVDAALREKRKALIAAYLDSPSDVVSQLPSLPMSANYFFCQLNRVIENLIKTENFDFTGVYDVGRCGISAVRNVAKTRRGFSGWYGRALMGDALLATSYLAHTSPTHVVAFIGDGAKGIVPDILPAFIDNILTHPQLLNKSITIFYFCNGGLSVINTYQERILFNRTSRQMRLVNVDQPAFEQTVDDFHIQGKTLTHFDEDTIRHALMTPKRLNLFSVVLGHNNEGDGISLATAKGWQRDPSDREALQERKDWAARQPESTSTSFDQGQNKEAIS
What is the function of this protein?
Involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig).  Catalyzes the decarboxylation of pyruvate, followed by the modification of the resulting two-carbon fragment acetaldehyde at the C3 position of the 2-octenal (1,2-addition of acetaldehyde) giving 3-acetyloctanal.
What are the official names of this protein?
Thiamine diphosphate dependent-3-acetyloctanal synthase PigD, ThDP-dependent enzyme PigD, Terminal condensing enzyme.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: PERK4_ARATH
Sequence: MASSPESAPPTNSTSSPSPPSNTNSTTSSPPAPSPPSPTPPQGDSSSSPPPDSTSPPAPQAPNPPNSSNNSPSPPSQGGGGERGNGGNNGGNDTPPSRGSPPSPPSRSNGDNGGSRSSPPGDTGGSRSDNPPSSGGSSGGGGGGRSNTNTAIIVGVLVGAGLLMIVLIIVCLRRKKKRKDSFYPEPMKGNQYQYYGNNNNNNASQNYPNWHLNSQGQNQQSTGGWGGGGPSPPPPPRMPTSGEDSSMYSGPSRPVLPPPSPALALGFNKSTFTYQELAAATGGFTDANLLGQGGFGYVHKGVLPSGKEVAVKSLKAGSGQGEREFQAEVDIISRVHHRYLVSLVGYCIADGQRMLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCHPRIIHRDIKSANILLDFNFDAMVADFGLAKLTSDNNTHVSTRVMGTFGYLAPEYASSGKLTEKSDVFSYGVMLLELITGKRPVDNSITMDDTLVDWARPLMARALEDGNFNELADARLEGNYNPQEMARMVTCAAASIRHSGRKRPKMSQIVRALEGEVSLDALNEGVKPGHSNVYGSLGASSDYSQTSYNADMKKFRQIALSSQEFPVSDCEGTSSNDSRDMGTKSPTPPK
What is the function of this protein?
Required during abscisic acid (ABA)-mediated activation of Ca(2+) channels.  Regulates ABA signaling pathways.  Modulates the expression of genes related to cell elongation and ABA signaling during root growth.
What are the official names of this protein?
Proline-rich receptor-like protein kinase PERK4, Proline-rich extensin-like receptor kinase 4, AtPERK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RIHC_ECOL5
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFTPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLNVKGFQQWVAEVLALVP
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: RPOC_SHIBS
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.