PharMolix/UniProtQA huggingface dataset:
Protein: GLSA_VIBC1
Sequence: MKPTAQILTDILAEVRPLIGQGKVADYIPALAKVPNTKLGIAVYTNEGEVIKAGDAEESFSIQSISKALSLTLAMCLYKQEEIWCRVGKEPSGQAFNSMIQLEMEQGIPRNPFINAGAIVVADLLQSRLSAPRQRLLEFARQLSGDTHIVYDKVVAASEMMHGDRNAAIAYLMRSFGNFENEVIPVLQNYFHACALKMSCVDLAKTFSYLANKGTSVQTGKPVVSPTQTKQLNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPELDASGNSLAGTKALELLAERIGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RMAR_SACPA
Sequence: MKLRLLNMILSMMNKTNNNNNNNINNKKLLLKNMLLDMNNKRMNNMKTMLKNNNMNINNKLQHLNNMNNWNTQIYNYNKNMEIMNIMNDKLINKLLYKMMTLKLNNMNINKIIMSKTINQHSLNKLNIKFYYYYNNDINNMNNNNNNYYMNMMNKLMNIMNNNMNNSLCNILSYYYNKKVTIESIKLSYIYLNSDIFSKYISLNDMNKYNNGILTNYQRMLNNIMPKLNDHNISMNYINNINNINNNKYNNMINLLNNNNNNNNNNNNNNNNYIDNINNIYNNMTIDNIPMDILMYKYLVGWSIKFKGRLNNNNGRTSTTNLLNGTFNNKKYLWSNINNNYKLNYIPSNHNLYNNSNINKNGKYNIKVKLNFI
What is the function of this protein?
Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
What are the official names of this protein?
Ribosomal protein VAR1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PYRD_SERP5
Sequence: MYYPLIRKALFQLDPERAHELTFQQLRRVTGTPLEFLIRQSVPTKPVSCMGLSFKNPLGLAAGLDKDGECIDAFGAMGFGFVEVGTVTPRPQSGNDKPRLFRIVEAEGLINRMGFNNQGVDNLVENVKKSHFGGILGINIGKNKDTPVEQGKDDYLICMDKVYPYAGYIAINISSPNTPGLRSLQYGEALDDLLAAIKNKQQELHERHHKYVPVAVKIAPDLSEEELIQIADSLVRHNIDGVIATNTTLDRKLIQGLNYCEQMGGLSGRPLQASSTEVIRRLSLELQGRLPIIGVGGIDSLMAAREKMAAGASLVQIYSGFIFKGPRLIKDIVNYI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS12_LISMF
Sequence: MPTINQLVRKPRQSKIKKSTSPALNKGLNSFKRELTDVNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRGQSRSKYGTKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ADRI_PENRW
Sequence: MEKSTLLSAVLKHRDALASVAEFLRILAGICWTLNYFSMLRTSQKDKIPSTGIFPLCNDIGWEFIYAFIYPKASAHWEGGVRVWFLVHCIVIFFIIKNAHNEWDYFPLIQRNLYFLYGIVTIGFAIGQYSFAREVGPDLGFFYGGVLCQTLASLGPIAQILSRNSTRGASLLLRAVATFGGFIKLTIYYLTGNAAGPWFESPMCKFYIGLTLILDFTYPICYYVIRRQELVNDEGDKKKKTKSGKAA
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
Terpene cyclase adrI, Andrastin A biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCC04_ARATH
Sequence: METTVDTTITWVIKNFSSLQSAPIYSDIFVVGGCKWRIMAYPKGINKAHDSFSLFLNVPDNESLPTGWRRHAKVSFSLVNQGSEKLSQRKVTQHWFVQKAFTWGFPVMITHTELNAKMGFLVNGELKVVAKIEVLEVVGKLDVSKESSPIMKTIDVNGFQVLPSQVDSVKRLFEKNLDIVSKFRLKNPYLKTACMNLLLSLTETLCQSPQELSNDGLSDAGVALAYLIETGLKLDWLEKKLDELKEKKKKEESCLVRLREMDEQLQPFKKRCLDIEDQISKEKEELLAAREPLSLYDDIDNNV
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At2g05410, RTM3-like protein At2g05410.
Protein: ORN_CORGB
Sequence: MSESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVHATEEELAQMDDFVTNMHESSGLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNSIATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRVYYKQPEKGLAHRALADIVESIRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_RICTY
Sequence: MNFLDESFLLAVSFVIFIYLIYRPAKKAILNSLDTKIIEIQEKVLKAKKLKEDAALLFEQTKVQIQKLEALRSQMIEESDKATQKIIQDKTKAMEEFLEQKKADAIQLIQNQKLIASKDLQDEFCDEVITLVSKYFRSVQLSERSIAKNLMDKSDFAHNASHATHLH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PFKA_ACTPJ
Sequence: MAKQIKKIAVLTSGGDAPGMNAAIRGVVRAALNEGLEVYGVQDGYYGLYTDRVIPLDRRSVSETINRGGTFLGSARFPQFKDPDVRKKSVETLKKYDIDALVVIGGDGSYMGAKLITEEFGYPCIGIPGTIDNDIVGTDYTIGYQTALETAVEAIDRLRDTSTSHQRISIVEIMGRHCGDLTISAALASGCEYIIVPEKGLDKESLMRNIEDGFNKGKRHAIIAITELMTDVQALAKEIEDRFGHETRATVLGHIQRGGAPCPFDRILASRMGVYAVDLLLQGHGGRCIGIKNENLVHHDIIDAINNMRRPFKEELFEAARKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_THERP
Sequence: MSRIGKRPIPIPAGVQVELTPDNVVRVTGPKGQLELRLHPKMIVQRENGVVQVQRPSDERFFKQLHGLYRTLIANMVQGVTEGFRKDLEIHGVGYRAALEGKTLVLTVGYSHPVRIDPPPGISFIVESPTRIGVVGIDKQLVGEVAAQIRRVRPPEPYQGKGIRYAGEVIRRKAGKTGKTKGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL12_MOUSE
Sequence: MPPKFDPNEVKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS
What is the function of this protein?
Binds directly to 26S ribosomal RNA.
What are the official names of this protein?
60S ribosomal protein L12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SL9A1_PIG
Sequence: MLLWSGICGLSPPRIFPSLLVVVALVGLLPVLRSHGLQPSPTASTIRGSEPPRERSIGDVTTAPPELAPESRPVNHSVTEHGMKARKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKAVGETPPFLQSEVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYDRVGIVDIVLGFLSFFVVSLGGVFVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGHLLDKNHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKTLPTERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNHLTVPAHKLDSPTMSRARIGSDPLAYEPKADLPVITIDPASPQSPESVDLVNEELKGKVLGLSREPGRATEEEDDDEDHDGGLVMRTKEPSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFIPKGQ
What is the function of this protein?
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions.  Major proton extruding system driven by the inward sodium ion chemical gradient.  Plays an important role in signal transduction.
What are the official names of this protein?
Sodium/hydrogen exchanger 1, Na(+)/H(+) exchanger 1, NHE-1, Solute carrier family 9 member 1.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with CHP1 and CHP2 at the reticulum endoplasmic and plasma membrane.
Protein: SFSA_YERE8
Sequence: MLSFNPRLQPATLIKRYKRFLADIVTPAGEVLTIHCANTGAMTGCATPGDAVWYSTSDNPKRKYPHSWELTQTQIGDWICVNTLRANELASLAIDNNQIVELSGYTSVKREIKYGDENSRIDLLLQAENRSNCYIEVKSVTLLQQQCGYFPDAVTLRGQKHLRELQSMVANGHRAVLFFAVLHTGIRQVAAARHIDNRYAELLAQAQQAGVEVICYGFQLSPDGIALDARLPLLLDETPNS
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MENC_GEOKA
Sequence: MAINIEYVILRHLQMELKAPFTTSFGTFQTKELILVEAVDCDGVSGWGESVAFSAPWYSEETVKTNWHMLEEFLVPLLFSKPLRHPAELPERFAAIRQNNMAKAALEGAVWDLYAKRLGVPLCQALGGTKKEIEVGVSIGIQPTVADLLQVIERYVAQGYRRIKVKIKPGWDVDVIRDVRRAFPDVPLMADANSAYTFADAKRLQALDEFGLMMIEQPLAADDLVDHARLQPLLQTPICLDESIRSYDDARKALDLGSCRIINIKIGRVGGLWEAKRIHDLCAERGVSVWCGGMLEAGVGRAHNIAITTLENFALPGDTAASSHYWERDIITPEVEVQGGLIRVPNAPGIGYEVDRRQVERYTQFAKVFHRTATA
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:16584181).  Also acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of various N-succinylamino acids, including N-succinyl-L-valine, N-succinyl-L-alanine, N-succinyl-L-methionine, N-succinyl-L-tyrosine, N-succinyl-L-serine, N-succinyl-L-isoleucine, N-succinyl-L-phenylalanine and N-succinyl-L-leucine (PubMed:16584181).  May be a bifunctional enzyme involved in menaquinone biosynthesis and in an irreversible pathway for the conversion of D- to L-amino acids, thereby facilitating the survival and/or growth of the organism (PubMed:16584181).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, N-succinylamino acid racemase, NSAR, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
Protein: TRUA_STRP1
Sequence: MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKIIIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHCRYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAAGTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNRQLAGPTISGNGLYLKEICYEN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: EFTS_NOVAD
Sequence: MAYTAADVKNLRERTGAGMMDCKKALDESGGDFEAAVDALRAKGLAAAAKKSSRTAAEGLVGVAVSGTKGVALEVNSETDFVAKNDQFQDFVRKATEVALNTAAADVEALKAAAYPDGGTVADKLTNNVATIGENQQLRRIKHVAVSNGIVVPYMHNAAATNLGKIGVLVALESEAAADKLEALGKQIAMHIAAAFPLALTADDLDAELIARERKIAAEKAAESGKPAEVQAKMVDGAVAKYAKENALLSQIFVMDNKSTIQQVVDAAGKEAGAKIVLKDYVRFQLGEGIEKEETDFAAEVAAAAGIK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK2_HORSE
Sequence: MSLSKKLTLDKLDVKGKRIIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGARSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEVEKACANPATGSVILLENLRFHVEEEGKGQDPSGNKLKAEAGKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGINLPQKASGFLMKKELEYFAKALENPERPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKANKNGVRITFPVDFVTADKFEENAKVGQATVASGIPAGWMGLDCGPETNKKYAQVMAQAKLIVWNGPVGVFEWDAFAKGTKALMDEIVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVDALSNL
What is the function of this protein?
Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis.
What are the official names of this protein?
Phosphoglycerate kinase 2, Phosphoglycerate kinase, testis specific.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPA_STAEQ
Sequence: MTVTIYDVAREARVSMATVSRVVNGNQNVKPETRNKVNEVIKRLNYRPNAVARGLASKRTTTVGVIIPDISNVYYSQLARGLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTISEEIKSLINQSSVPVVVSGTDGKDDHIASVNIDFKQAAEEATQYLIEKGAKTFSLIGGEYSIKAQDDVLEGLKNVLSQHQLKLDDTLHLTGNESYKSGIKTFEQLQSNLPDAVLCISDEQAIGILHSAQDAGVKVPEDLQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEEIENPNVILPHRIEYRGTTQ
What is the function of this protein?
Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
What are the official names of this protein?
Catabolite control protein A.
Protein: HSF_CANAL
Sequence: MIMNMTTDYRDPLLDLFGTESNSGNETSSPSDIPVINRSGTFNQQQFSPLLTQQSLYNTPNSGSTPNIFDPNYTQMQEEQTSPSSNKLQPEDPPRKKRNTRSQTKIHQQSEGDEYNSNDYKDSIDLDKPPVVEPSPPFFVESDTTPEFVIPTPTSEQQQQQHHELIAQDYQRSNNSNQFGNLTHYEPNLPPLPPLSESILPQTNTFHPLVLPHDPRHAITAGPANNSQQQQQQQQQDSSIPSDGISSKIQQLHAPSLSNNQSASQRKKKESSGPKTRPAFVMKIWSMVNDPANHEYIRWNDDGKTFQVFHREDFMKVILPKYFKHNNFASFVRQLNMYGWHKVQDVANGTLNQNSDKNGQDEIWQFENPNFIKDREDLLDKIVRNKSSSNQDDVSGVSFNGINNSANLSLILQELETIKMNQYVISEDLRRVRQDNKMLWQENYLNRERNQVQGRTLDKILKFLSVVYGNNANKILNGHGFADFNDSNNIMTQYRPSPMGSPLLSRPQTQPPPSNSRFARDNNQTAQPTYESPLSTSDTNNNNNNTFEYQQAVNRPRLMLTNRAHSRRPSMSRTKSTPEGSIEEIIRSYSNDKAAESNVNRMYEQLVGHQPGATTNNNNHSSSTAISAPSPRHSFLQELNLPGTPRNLDDLEKHINKEGQSIQQVQDWIDKLAQEQHEKQQQQQGNDDDDDFDVNEFLKDATTTPSSNVPNGGHYNNGNISFVGSPIAMTPGSNVSSNINDSDGNEKKSKKRSIEEVSDH
What is the function of this protein?
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.  With HSP90, is required for the modulation of the chaperone levels in response to growth temperature, rather than the activation of acute responses to sudden thermal transitions.  Activated during infection and contributes to full virulence.
What are the official names of this protein?
Heat shock transcription factor, HSTF, Heat shock factor protein, HSF.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOD_PHOLL
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLENVRQVNDVRGMLGFTGTYKGRPISVMGHGMGIPSCSIYAKELITDFGAKVLIRVGSCGSVRHDVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDLVRNAVDAAKAKNINVRVGNIFSVELFYTPDPQLFDIMEKYGILGVEMEAAGFYGVAAEYGAKALTICTVSDHIRTHEKLTAEERQTTFNEMIEIALESVLLGDK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: KLHDB_DROSI
Sequence: MGDLPGSGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDEFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: HSP7M_DICDI
Sequence: MLRSLKALKLNSLNAQKGIRQFCSDSKISGQVIGIDLGTTNSCVAVMQGAEARVLENAEGGRTTPSVVAFTEDNQKIVGLPAKRQMVTNAENTLFATKRLIGRRFDDPMTKKDMTMVPYKIVKGPNGDAWFEVKGKMISPSEAGAMVLQKMKETAETNLGGPVTDAVITVPAYFDDSQRQATRDAGTIAGLKVQRIINEPTAAALAYGFKKDEPKTVAVYDLGGGTFDISILEIVGGVFEVRATNGDTFLGGEDFDNALLEHFVAEFKKEKGIDLTKDTMATQRLREAAEKAKCELSSTLTTEINLPYISAGPSGPVHFNMKLTRSKFEQLVADLIQRTIGPCNICLKDAGLSTSEINEVILVGGMTRMPKVQELAKSTFNKEPFKGVNPDEAVAVGAAIQGGVLKGDTKGIVLVDVTPLSLGIETLGGVFTRLIKKNTNIPASKTDTFSTAADGQSEVEIKVFQGEREMAVDNKLLAKFTLFGLPPLPKGVPQIEVTFDIDVNGMLQVIAKDKATGKAQQVRIQTSGGLSKDDIARILKESEANAEVDRKRKELVEARNNGESVVYQVEKDLVEFKDYLSQPQTEEIKKAVQAVRDVLAKEDGSAIEAEIKKLHDLTRSSFETAYKAKLDSSASKSSSTENKENKDNTTEAEFTEKK
What is the function of this protein?
May function in protein folding and assembly, and disassembly of protein complexes.
What are the official names of this protein?
Heat shock 70 kDa protein, mitochondrial, 75 kDa glucose-regulated protein homolog, GRP-75.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PUR9_LACP3
Sequence: MKRALLSVSDKTGLVSFAKGLIDRGFELVSTGGTHRELAAAGIAVTSVEEVTGFPEMLDGRVKTLHPKIHAGILARRDDPAHMEALADHDIQPVDLVCVNLYPFAATIKRPDVTRAEAIEQIDIGGPSALRAAAKNSDSVWAVVDPADYEAVLTGLDQDDAHLRQKLAAKVFAITAAYDAQIVHYLDPEPFPEHFTPTYTKRQDLRYGENSHQQAAFYVEPDPNPTSLAAAKQLHGKELSYNNIKDADAALAMLREFSEPAVVAVKHMNPCGIGLGKTIEGAWDKAYAADPMSIFGGIIALNRPVDLATAEKMHKLFLEIIMAPAFDDDAYAVLAKKKNVRLLTINTADTPAELGTETTAIYGGLLIQARDNQTETPADLTVVTTVKPTDEQLKALAFAQTVVKHVKSNAIVVAQADQTLGIGAGQMNRIGSVELALTQAQQNDNFAGAVMASDAFFPMDDCVDYAAKHDIKAIIQPGGSIRDKDSIEKANQYGIAMVTTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: NPIIA_ASPTN
Sequence: MRFTALATAILPLACNVLALPAKTGEAPKLDVSLSQVDNTLIKAVVKNTGSEDITFVHLNFFRDKAPVKKVSLFRNATELPFQGIKQRFRTEGLTEDALTVLAPGESIEDEFDIAATSDLSEGGSITISTDGFVPIATGNKITGSVPYSSNELSIEVDAAQAASVASAVKPLDKRTKVASCSGTRSSALSTALKNTVSLANAAASAAQSGSSSRFQEYFKTTSSSVRSTVAARFRAVASEASSTSSGSTTYYCTDTYGYCSSNVLAYTLPAYNIIANCDIYYTYLSALTRTCHAQDQATTTLHEFTHAPGVYSPGTDDLGYGYDAATALSSSQALNNADTYALFANAVNLNC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog ATEG_04941, Deuterolysin ATEG_04941.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_OCEIH
Sequence: MSFKNKLKDYFMGDEYEYEYVDEDNQSEEPTQKEAKVNPKNVVNLSSVQQSNSRVVLIEPRNYNEAQEIADNIVNRRAVIINLQRVDHQQAKRIVDFLSGTVYAVKGDIQKLGAETFLCTPDNVEVSGTITEMLYEQEEYDKGW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PGFS_LEIMA
Sequence: MAGVDKAMVTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGKLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRYGPDPDEAQF
What is the function of this protein?
Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2.  Has also aldo/ketoreductase activity toward the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde.
What are the official names of this protein?
9,11-endoperoxide prostaglandin H2 reductase, Prostaglandin F2-alpha synthase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOK3_HUMAN
Sequence: MTRGARLRSDARAQLNQLSLDGGTGSGQKGKCEEFPSSLSSVSPGLEAAALLLAVTMDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAGAIARQRERLPELTRPQPCPLPRATSLPSLDTPGELREMPPGPEPPTSRKMHLAEPGPQSLPLLLGPEPNDLASGLYASVCKRASGPPGNEHLYENLCVLEASPTLHGGEPEPHEGPGSRSPTTSPIYHNGQDLSWPGPANDSTLEAQYRRLLELDQVEGTGRPDPQAGFKAKLVTLLSRERRKGPAPCDRP
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1.  May modulate ABL1 function (By similarity).
What are the official names of this protein?
Docking protein 3, Downstream of tyrosine kinase 3.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.