PharMolix/UniProtQA huggingface dataset:
Protein: KI15A_XENLA
Sequence: MPPGTKGDPSNVTQPLPCLPSAEEDAIKVFVRIRPPVEGTLTGVDGEQGLCLTALSSTTIRLHSKPEPKMFTFDHVANVDTNQESVFSSVAKNIVESCMNGYNGTIFAYGQTGSGKTFTMLGPSESDNFTHNLRGVIPRSFEYLFFLINREKEKAGEGKSFLCKCSFIEIYNEQIFDLLDSASAGLFLREHIKKGVFVVGAVEQVVTSAAEAYQVLSMGWRNRRVASTSMNRESSRSHAVFTVTIESMEKTNDLVNIRSSQLNLVDLAGSERQKDTQTEGVRLKEAGSINRSLSCLGQVITALVDVANGRQRHICYRDSKLTFLLRDSLGGNAKTFYIANVHPGSKCFGETLSTLQFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKKLKEQLSQLLSGQMPGDISVARVPSVGDNNMDYMNNFIEAMMILEKSDREKKVLLQKVVQLEDLCNKKEKFIQSNKMIVKFREDHISRLEKAHKEGRISLSNNEQDDFIAELKEEIRTLKEQVEHHPRVAKYALENHSLREENKRLHSLQSVKRAQEVTAQMIAELEKAFLEVSVSEKDRQVAPMHSTPIQLDNNSLMSAARMRERMLQLESELATSKQEYEEFKELTKKKQVEQESELQSLIKSNQHLENILEAIKANKRHEVSQLNRMHAAETIKNMTTPTKSYNLRSRLVPRLSPDAMPNGLMDTPKSGDVMDDIINEPIPPEMSEQAYEAIAEELRIVQEQVTALQAKLDEEEGKNIRLQQQVNKLELCSTQIQELFNSERSNWNKEQQDLIAQIKSLEKQKQENKSQEDVLKSEVHDLRVVLQSADRELGAVKGEYSLYREKQEKELSQLSARHMDVQLQLDNVRLEHETLLEEKRSLQDAFDNLEEVMKFEIDQLKQEISDSKHENETLRAEFSNLLELLETEKERRQKLTSQLEEDKENKTKELLQVVDENMHLRKQCSELMTKCEQQVTELHGLEHSLTSSKEMIADLEKKNTADKEVVADLMNQIQVHRTTIIHKTESIDLLTRELEDIHSKYSIVLLAKEESKTVIEEQEKQIEELRECLERKQSADNIEKELLCDDLAHATEELEKLTEAFNKQEALLHTHEKELVEKEQQISELTNQVKLMTDLEISREQEKIRPASSNSSSPVVLPETPRTPEGNPYDSEIANLQKRNTNLEILVSELNEERTSKNEEIIRLKMQLCETENMRLEIQNLQGMCKELKSQLENCNNVMKDSNDQKPSDMQDLKREIEKEVSERMEKGKATEHILKLQAELEETRNILCTKDHSLNELSKEIERTRSLEAKAFTEKEEIRSILEGKYEETEKLSHELDMLRKQVLFLAEENGKILGHQNPNQKIQYLVKLKKENNKLLEEAEKLRIENLFLKESKKCEHCN
What is the function of this protein?
Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.  Required for centrosome separation and maintenance of spindle bipolarity during mitosis.
What are the official names of this protein?
Kinesin-like protein KIF15-A, Kinesin-like protein 2-A, Xklp2-A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KLP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes during metaphase on spindle microtubules, with a strong enrichment at spindle poles. Localizes to the minus ends of spindle pole and aster microtubules in a dynein- and dynactin-dependent manner. Detected diffusively in the cytoplasm. Localized (PubMed:8548825) at the centrosome during the interphase and throughout mitosis.
Protein: ARFC_MYCBP
Sequence: MEHVHWWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKSVRGSSAKSKPPTARKPAVKSGTKREESPTAKTKVATESAAEQIPVAGEPAAEPIPVAGEPAARIPVVPYAPYGPGSARAGADGSGPQGWLVKGRSDTRLYYTPEDPTYDPTVAQVWFQDEESAARAFFTPWRKSTRRT
What is the function of this protein?
Required for ammonia secretion (By similarity).  Also required for wild-type expression of ArfA.
What are the official names of this protein?
Uncharacterized membrane protein ArfC.
What is the protein family that this protein belongs to?
Belongs to the ArfC membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS20_MYCBO
Sequence: MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MSRB_VIBCM
Sequence: MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTGLYHCTCCQSALFSSENKYDSGCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHLGHVFEDGPKTTGLRFCVNSVSLIFNKK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: HSLU_CYTH3
Sequence: MTALQGFLTPTEIVAELDKYIIGQHDAKRNVAIALRNRWRRMHADADMRKEIMPNNILLIGPTGVGKTEIARRLAKLADAPFTKVEASKFTEVGYVGRDVESMVRDLVEQAVNMVKTQKKEEVKIKVSQVVEDILLDLLIPPVKSTGMGFKTASTQSIDTNEIPDNDQELNERTRELFREKIRSGELDERKVEINVQQQGPGVGVVGGAMDEASMMNIQEMIGNMMPKKTKKRKLSIAEARKILLEEESAKLIDMDDVKDEAIRKTENMGIIFIDEIDKVASSKKGNGPDVSREGVQRDLLPIVEGSAVNTKYGTVHTDHILFIAAGAFHVSKPSDLIPELQGRFPIRVELNSLTEADFYHILKEPKNALTRQYQALLSSENVNIEFHDDALKAISEIAFELNVEVENIGARRLHTVMSHLLNELLFDVPDKIETHSTVVITKELVDQKLKGLVKNRDLSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECN_XYLFA
Sequence: MLRHLTIKDFAVVRNIELEFGPGMTVVSGETGAGKSLIIDALGFLSGLRADSSVVRHGAERAELSAEFNITIHHPARVWLRNVELDDADQCQLRRIIRADGGSRAWINARPVTLSQLSDLATHLVEIHGQHEHQTLLSRQSQLVLLDAYAQNETERDAVQQAAAHWQALLDERDALQAQGDMSERINFIEHQLTELQRENLDPATITALDASHRRQAHTAALIEACKNTTQTLNGDDTTSALHLLHAARHTLSRVTEHDARLGEVETLLDNAMIQVDEALTLLDRIHNDLNIDPEQLEAIELRIGRLHSLARKYRCTPLDLAAQRDRMAAEVESMRNMDIHLQQLDHRISNAMTKWRQAAEKLSISRTRAAAALSTTTTNLINELGMGGGQLLIQLQPHENNRPHPNGAERTEFLIATNPGQPPRPLRKIASGGELSRVSLAIMVAALGLDTVPTMVFDEVDTGIGGAIADIVGQKLRALGEQHQVLCVTHLPQVAAKGHTHYRVSKIPIDGITQSAICLLDSQERQEEIARMLGGVHISKEAHAAAGKLLQELQEM
What is the function of this protein?
May be involved in recombinational repair of damaged DNA.
What are the official names of this protein?
DNA repair protein RecN, Recombination protein N.
What is the protein family that this protein belongs to?
Belongs to the RecN family.
Protein: MNMC_SHEB9
Sequence: MTAEPNKPCQIKRDYQQLINLYPATAHTDAHYLSKLSIYQQRVFEAHSQQKLLILGQIGLGNGLELLSWWRTQANPSQRLLLKVFEPNPINAYELKSLWDQSLTLVKETPFEPHLESKQASALECKSKLSQLAQTLLDAEPTAIIGCQRLIFDDGRTTIDLHFGDIQTQLSSLTHSPMHPVQHWLILPHLLQALYHQSQWQMAKLSDDSATIATIGLSESSELSETTVNRFQACGFTVSDINELGTKALGIHQPVTLINHQPDAVLLHERQVLRQQDAKAYAFNPMAAILSSPTQSSIAIIGGGLASAHLTLSLAERGQGAQVFCKDAELGQGASGNRQGAIYPLLTTENDELSRFFQQAFLFSRRRVQALTSAPADNQTPISHNFCGVLQTAHDERSQLRLDKIIQGQPWPSEIAYAVDAEQANAIAKINLDKPGFFYPLGGWVCPFEYADAAIQKAMQLADVSVSLNTDILAIERQADGWVLLTEKERFGPFAQLVLANGAELTQFDASNKLQISPFRGQVSHVPAQFQLSQLATVLCANGYLTPSHQGLHCLGASYVKEPEHLDFCSQEQQENLMKMHESYPNQSWLEDIDMSGNNARIGVRMVTRDHFPMMGCAPDVAKILEDYEQHQLTKESRHYWQTTPAPVHQGLYILGGLGSRGLSSGPLAAECLAAQLCGEPIPLDKETLCKLNPNRMWLRKLLKGKAL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP2AA_BACLI
Sequence: MSLGIDIHVKESVLCIRLTGELDHHTAETLRKQVSGHLEQTDIRHIVMNLADLSFMDSSGLGVVLGRYKEIKQLGGEMIVCAISPAVKRLFDMSGLFKIIRLEQSEQRALETLGVAS
What is the function of this protein?
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.
What are the official names of this protein?
Anti-sigma F factor antagonist, Stage II sporulation protein AA.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: CHS4_NEUCR
Sequence: MSLPRRPGPSPPHEEPRRYRQSGSRRSRPPPADVETGYAPMAGERPSQQQRVPSISSFPETLPSPNPNVERDPLAPTPEPAHPSGIPQRKRSLIRPERNRIGKDHPNYHYRKHAANMNTLPSSTGHDPIYEDLEGATDDVSGTGSRNDDDVSEESPPRRKHSTKMQVIETEKSGDERRRRRKSDTTKHGKIVKASKGKREKSGGLPTPSFWNIYCGFVTFWCPGFVLKCFGMPEMAQQRAWREKMGLISIILLIMGFVGFITFGFTQVVCGKPPLRLRINEVGSGYMIFHGSAYDLTKSHHPPAEGIPRRPDGLGANVIYDLPQHYGGQDGSFLFQNVNGKCKGLITKQENSDVPSDKSGNLAWYFPCNTFNQDGSSKPNTTIPYYLGYACHTTANARDSFYLGLKSSADVYFTWDDIKNSSRNLVVYSGHVLDLDLLHWFNDTQVTYPARFKELRDKNTAGNQAIRGRDITHAFQSSKDKQIAECFEEIIKVGSVDTETVGCIASKVVLYVSLVLILAVVLARFVLALIFQWFISKTYAAAKTSQTSDQRKRNRQIEDWTEDIYRAPPRLPGEVGSSVAGSSDRQSKRSSAFLPTHSRFSTVYGNERGNRKPGLPTTMASQNAAGQLLHPGTIYGQGNESRSSFLKSDAYGSSSSPADGPGPAGFIHEAVVPQPPSDWMPFGFPLAHTICLVTAYSEGEMGVRTTLDSIAMTDYPNSHKVILVICDGIIKGHGEEHSTPDIILGMMKDHTIHPDDVEPFSYVAVATGSKRHNMAKVYTGFYDYGTNSAIPLEKQQRVPMMMVVKCGTPAEASKSKPGNRGKRDSQIILMSFLQKVMFDERMTELEYEMFNGLWKITGISPDFYEIVLMVDADTKVFPDSLTHMISAMVKDPEIMGLCGETKIANKRASWVSAIQVFEYFVSHHLAKAFESVFGGVTCLPGCFCMYRIKAPKGAQNYWVPILANPDVVEHYSENVVDTLHKKNLLLLGEDRYLSTLMLRTFPKRKQVFVPQAVCKTTVPDEFMVLLSQRRRWINSTIHNLMELVLVRDLCGTFCFSMQFIVGIELIGTLVLPAAIAFTFYVVIISIINSPPQIIPLVLLGLILGLPAILVVVTAHSWSYIIWMFIYLLSLPVWNFVLPTYAFWKFDDFSWGDTRKTAGEKSSKGGHGEAEGEFDSSMITMKRWAEFERDRRVRSTYWAGSRDNVISGVGGSNGWGSSQPRGHEQGRHFDDYFSDA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 4, Chitin-UDP acetyl-glucosaminyl transferase 4, Class-IV chitin synthase 4.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPIDR_HUMAN
Sequence: MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGLEEIELLSAGGASAEH
What is the function of this protein?
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR).  Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
What are the official names of this protein?
DNA repair-scaffolding protein, Scaffolding protein involved in DNA repair.
What are the subcellular locations of this protein?
Nucleus. Note=Together with BLM, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment.
Protein: RRF_RHIE6
Sequence: MSEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRVPLNQVANITVPEPRMLTVSVWDKSMVSAVERGIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHDYAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDESRAQSERVQKMTDETISEIDRLLGEKEKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRRM3_MOUSE
Sequence: MSSTVNNGATGMPAPPDAANGFPQPGASSGSWPRAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGAHIVAETPRRMEGLEPGLEYPPFDEDDGPVDCDCPVSCYRGHRGYRTKHWSSSSASPPPKKKKKKKGSHRRSRKKRRLESECSCGSASPLRKKKKNVKKHRRDRSDSGSRRKRRYRSRSLKSKRKEKNKERKRPHTESPGRRFHHHSSASSHSPSMSSHYSDSGSPSRLSPKHRDDGRKTGSQRSSGSRSPSPSGGSGWGSPQQNGGSRQRSGAHGGRPGSAHSPPDKPSSPRACDKAAAAPTPPARGKDSQSPRSAPSSQGRGGRAAGGTARRRRRRRRRRRSRSSANAPRRRGRRRTKPAPPRGSSRSLSGAHSSSDSGGGAPGPGPEPCSERGHGGHGKRAKERPPRARPASTSPSPGTRGRRGGPEGNSSSRSPGPHQGSWSSSRSPSKSHSRSPDKRTRSPSLSPSPKKPLGRDKDSEGRARHAEAEAARTRRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSTDYSSRSHSRSPSPGHSHGSYSSRSHGTRSRSCSASRSRSPSYHSRSSSESGGF
What is the function of this protein?
May play a role in regulating breast cancer cell invasiveness.  May be involved in RYBP-mediated breast cancer progression.
What are the official names of this protein?
Serine/arginine repetitive matrix protein 3.
What is the protein family that this protein belongs to?
Belongs to the CWC21 family.
Protein: IPK_THEAC
Sequence: MMILKIGGSVITDKSAYRTARTYAIRSIVKVLSGIEDLVCVVHGGGSFGHIKAMEFGLPGPKNPRSSIGYSIVHRDMENLDLMVIDAMIEMGMRPISVPISALRYDGRFDYTPLIRYIDAGFVPVSYGDVYIKDEHSYGIYSGDDIMADMAELLKPDVAVFLTDVDGIYSKDPKRNPDAVLLRDIDTNITFDRVQNDVTGGIGKKFESMVKMKSSVKNGVYLINGNHPERIGDIGKESFIGTVIR
What is the function of this protein?
Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.  Has lower activity with isopentenyl thiolophosphate (ISP).  Has low activity with dimethylallyl phosphate (DMAP), 1-butyl phosphate (BP) and 3-buten-1-yl phosphate (BEP).  Has no significant activity with geranyl phosphate (in vitro).
What are the official names of this protein?
Isopentenyl phosphate kinase, IPK.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl phosphate kinase family.
Protein: RS8_STRCO
Sequence: MTMTDPIADMLTRLRNANSAYHDSVTMPASKIKSHIAEILQQEGFITGWKTEDAEVGKNLTLELKFGPNRERSIAGIKRISKPGLRVYAKSTNLPKVLGGLGVAIISTSHGLLTDKQAGKKGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RUVB1_DEBHA
Sequence: MVQINEVKDTQTRESRTAAHTHIKGLGLDEHGIAKRVEGGFVGQSDAREACGIIVDLIKSKRMSGKAILLAGAPGTGKTALALAISQELGPKVPFCPIVGSELFSAEIKKTAALMENFRRAIGLRIKETKEVYEGEVIELTPEEAENPLGGYGKTISHVIVGLKTAKGTKSLRLDPSIYESIQKERVSVGDVIYIEANTGSVKRVGRSDAYATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVLSMMGQLLKPRKTEITDKLRSEVNKVVSKYIDQGVAELIPGVLFIDEVNMLDIECFTYLNRALESSIAPIVVLASNRGMTTIRGTDDDKKSPHGCPADLIDRLLIVRTLPYNQEEIKIIISKRATLENLIVTPDALDKLSLHGINNSLRYALQLLAPAGVLSKTAGRNEITSEDIEECEILFLDSRRSIKILEETKGYL
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 1.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRET1_APILI
Sequence: MGVENTKQTMSSQNIKPAKDSDDVLHTQFKEVKRSPMRYTMQLLAALAVSMASLMIGYSSSYTSPALVSMRDNTTATFEVTMDMAMWIGSIMPLSALIGGIIGGPCIEYIGRRNTILSTALPFLAGWLFIALATNVAMILVGRSICGFCVGVASLSLPVYLGESIQPEVRGSLGLLPTVFGNSGILMCFTAGMYLAWRNLALLGACIPIIFLILMFLIPETPRWYISKGKIKEARKSLQWLRGKTADISEELDSIQKMHIESERIATEGALIELFRKNHIKPVFISLGLMFFQQFSGINAVIFYTVQIFKDSGSTVDENLSTIIVGLVNFISTFVAAMIIDRLGRKMLLYISSILMCITLFTFGTFFYVKELMDVTAFGWIPLMSLIVYVIGFSFGFGPIPWLMMGEILPVKIRGTAASVATAFNWSCTFVVTKTYEDLVLHIGPYGTFWLFGTLVAVAFIFVIICVPETRGRSLEEIERRFAGPVRRTSAIANLKPMPITI
What is the function of this protein?
Moderate-capacity facilitative transporter for trehalose.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph.
What are the official names of this protein?
Facilitated trehalose transporter Tret1, AmTRET1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PI5K1_ARATH
Sequence: MSDSEEDEEEEEASEVILSSVVQKKKKKNLRFGEEVERRDGLVLLAQSTPMVRSRSQGTTRRVTPTPLVDVEKPLPNGDLYIGSFSGGFPHGSGKYLWKDGCMYEGDWKRGKASGKGKFSWPSGATYEGEFKSGRMEGFGTFTGADGDTYRGTWVADRKHGHGQKRYANGDFYEGTWRRNLQDGRGRYVWRNGNQYTGEWRSGVISGKGLLVWPNGNRYEGLWENGIPKGNGVFTWSDGSSCVGAWNESNIMRSFFNGVEKNDLIVGNRKRSSVDSGAGSLGGEKVFPRICIWESDGEAGDITCDIIDNVEASMIYRDRISVDRDGFRQFKKNPCWFNGEAKKPGQTISKGHKKYDLMLNLQLGIRYSVGKHASIVRDLKQTDFDPKEKFWTRFPPEGTKTTPPHQSVDFRWKDYCPLVFRRLRELFQVDPAKYMLAICGNDALRELSSPGKSGSFFYLTQDDRFMIKTVKKSEVKVLLRMLPSYYKHVCQYENSLVTRFYGVHCVKPVGGQKTRFIVMGNLFCSEYRIQRRFDLKGSSHGRSTAKPEGEIDETTTLKDLDLNFSFRLQRNWYQELMKQIKRDCEFLEAERIMDYSLLVGVHFRDDNTGEKMGLSPFVLRSGRIDSYQNEKFMRGCRFLEAELQDMDRILAGRKPSIRLGANMPAKAERMARRSDFDQYSSGGASYPSHGEMYEVVLYFGVIDILQDYDITKKIEHAYKSLQADPASISAVDPKLYSKRFRDFISRIFIEEG
What is the function of this protein?
Catalyzes the synthesis of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4-bisphosphate.
What are the official names of this protein?
Phosphatidylinositol 4-phosphate 5-kinase 1, AtPIP5K1, 1-phosphatidylinositol 4-phosphate kinase 1, Diphosphoinositide kinase 1, PtdIns(4)P-5-kinase 1.
Protein: MNTH_YERPE
Sequence: MLNGRAVDTSRRPLRKIKLSLMGPAFIAAIAYIDPGNFATNIQAGATFGYTLLWVVVWANVMAMLVQLLSAKLGIATGKNLAEHIRDRFPRPVVWAYWVQAEIIVMATDLAEFIGAAIGFKLLFGVTLLQGAVLTGIATFLILMLQNRGQKPLELVIGGLLLFVAAAYIVELIFSQPDIAALGRGMLIPNLPDGNAVFLAAGVLGATIMPHVIYLHSALTQTGGEESKTERYASTKFDVAIAMTIAGFVNLAMMATAAAAFHFNGYENIAEIEEAYITLQPLLGNAAATVFGLSLIAAGLSSTVVGTLAGQVVMQGFVRFYIPMWVRRIVTMLPSFIVILAGMDATQILVMSQVLLSFGIALALVPLLVFTGNKELMGELVDTKTTQILGKLVVLIVVGLNAYLLISLL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRP41_THEAC
Sequence: MKRMEANKIKLINEDNLRLDGRSFNELRPIKIQAGVLNRADGSAYIEWGGNKIMVGVYGPKEAYPKHSQDIDHAIVKARYNMAAFSVDERKRPGPDRRTMEISKVISEALSSSIMIEQFPRAEIDVYIEVLQADAGTRIAGLTAATVALADAGVPMRDMVVGCTAGKVDGHMVLDLSKEEDNYGEADIPIAIMPKTGDIVLMQMDGDVTEDELYQAMDMIFEATKRISQIQREALLNKYKIQDIGEGE
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_VESOH
Sequence: MKVDLTGLRREFTQSGLNRTDLDNSPFGQFNLWFEQAQKADIIEPSAMSLATSDNNEIGIRTVLLKYFDMYGFVFFTNYNSKKSKELQSNPNVALLFPWLVLERQVKISGYVEKISMLESLKYFSSRPKASQLGSWASQQSSSLSSRKVLLSQFELMKVKFSNGKVPLPDFWGGYRVVPLKIEFWQGRENRLHDRFIYQLNKGKWRIERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YGFB_ECOL6
Sequence: MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: GYRB_BACAN
Sequence: MEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIRVTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIPVADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHLNRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSNLTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKARELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRTIITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEKELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYVKNLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_SALSV
Sequence: MEISWGRAMWRNFLGQSPDWYKLALLVFLIINPFIFLANPFIAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMVLSLAFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRGEENDMLDDSHIDPHYKTVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCMLVEKMRWFGYGETLPEKVRDVLQQFDDQSRKKRTRQDKLKLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATALTGVTDEHAIGKAFTESLPFTALLTVFFSIVAVIIDQHLFAPIIQFVLQASEHAQLTLFYLFNGLLSSISDNVFVGTIYINEAKAAMENGAISLKQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLIGLLCVEFTLAPVTEWMTQAGWLATLS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BAMS_SOLLC
Sequence: MWKLKIAEGQNGPYLYSTNNYVGRQTWEFDPNGGTIEERAKIEEARQQFWNNRYKVKPSSDLLWRIQFLGEKNFKQKIPAVKVEEGEEISHEVATIALHRAVNFFSALQATDGHWPAENAGPLFFLPPLVMCMYITGHLNTVFPAEHRKEILRYIYCHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGVNNACARARKWILDHGSVTAIPSWGKTWLSILGVFEWIGTNPMPPEFWILPSFLPVHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYDRPYDEINWKKVRHVCAKEDLYYPHPLVQDLMWDSLYICTEPLLTRWPFNKLRNKALEVTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYLWVAEDGMKMQSFGSQEWDTGFAIQALLASEMNDEIADTLRKGHDFIKQSQVTNNPSGDFKGMYRHISKGSWTFSDQDHGWQVSDCTAEALKCCLLLSTMPRELVGQAMEPGRLYDSVNVVLSLQSKNGGLAAWEPAGASEYLELLNPTEFFADIVIEHEYVECTASSIQALVLFKKLYPGHRTKEINIFIDNAVKYLEDVQMPDGSWYGNWGVCFTYGSWFALGGLVAAGKSYNNSAAVRKGVEFLLRTQRSDGGWGESYRSCPDKVYRELETNDSNLVQTAWALMGLIHSGQADRDPKPLHRAAKLLINSQMEDGDFPQQEITGVFMKNCMLHYAAYRNIYPLWGLAEYRKNVLLPLENN
What is the function of this protein?
Oxidosqualene cyclase converting oxidosqualene into beta-amyrin, generating five rings and eight asymmetric centers in a single transformation.
What are the official names of this protein?
Beta-amyrin synthase, Triterpenoid synthase 1, SlTTS1.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.