PharMolix/UniProtQA huggingface dataset:
Protein: RS13_RHORT
Sequence: MARIAGVNIPSNKRVCIALTYIYGIGRTKAGEICERTGIAENRRVNDLSDDEVVRIREIIDSEYKVEGDLRREVAMNIKRIMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPAKPIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ARHB_XENLA
Sequence: MDALKSAGRAIIRSPSIAKQSWGGGKHKKLPENWTDTRETLLEGMLFHLKYLGMTLVEQPKGEELSATAVKRIVATAKASGKKLQKVLLKVSPRGIILYDSASNQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNETLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSRENKDKREKSGSDGEGASSSQSDGSSSITSLKASASANLLDFEDCTKAFDVLNASDNHIEDLFRQNSTNENNNIVWELDDGLDEAFARLAESRTNPQVLDIGLTANDLQSEECLSPTSWDKLELNPAEADELFMF
What is the function of this protein?
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR).  Also involved in the vitellogenin receptor mediated endocytosis of nutrients during oogenesis.
What are the official names of this protein?
Low density lipoprotein receptor adapter protein 1-B, Autosomal recessive hypercholesterolemia protein homolog beta, ARH beta, xARH beta.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_NEIMF
Sequence: MAKVSKRLKALRSSVEANKLYAIDEAIALVKKAATAKFDESVDVSFNLGVDPRKSDQVIRGSVVLPKGTGKITRVAVFTQGANAEAAKEAGADIVGFEDLAAEIKAGNLNFDVVIASPDAMRIVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVQYRTDKAGIVHATIGRASFAEADLKENFDALLDAIVKAKPAAAKGQYLKKVAVSSTMGLGIRVDTSSVNN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DXS_BURO1
Sequence: MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSKTGGHLSSNLGTVELTIALHYVFNTPNDRIVWDVGHQTYPHKILTGRRDQMHSLRQYDGISGFPRRSESEYDTFGTAHSSTSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPVLELARKLEEHAKGMVVPATLFEEFGFNYIGPIDGHDLDSLIPTLQNIRELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPSTTPAKKTYTQVFGEWLCDEAERDTRVVGITPAMREGSGMVEFEKRFKDRYYDVGIAEQHAVTFAGGLATEGLKPVVAIYSTFLQRAYDQLIHDVALQNLPVVFAIDRAGLVGADGATHAGAYDLAFMRCIPNMTIMAASDENECRQMLHTALQQPNPTAVRYPRGAGTGVATVKEFTEIPLGKGEVRRRTSQPEGKRVAILAFGTMVAPSLAAAEELDATVANMRFVKPVDAALVRELAETHDYLVTVEEGCVMGGAGSACVEALMESGVIRPVLQLGLPDQFVDHGDHAKLLAQCGLDGAGIAKSIRERFLSPAADVAGHAKRVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y1702_BRUAB
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKQGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAIKKAAGNDGENYDEVRYEGRGPGGVSVIVEALTDNRNRTASNVRAAFTKSGGSLGETGSVSFMFDRVGEIVYKPEAGDADKVMEAAIEAGAEDVQSGEDGHVILCAFEDIGEVSKALEAALGEAESIKTIWKPQTNTELDEEKARSVLKLLSVLEDDDDVQNVYTNFEVSDEVMEKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein BruAb1_1702.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VANR_ENTFA
Sequence: MSIRILLVEDDDHICNTVRAFLAEARYEVDACTDGNEAHTKFYENTYQLVILDIMLPGMNGHELLREFRAQNDTPILMMTALSDDENQIRAFDAEADDYVTKPFKMRILLKRVEALLRRSGALAKEFRVGRLTLLPEDFRVLCDGTELPLTRKEFEILLLLVQNKGRTLTHEIILSRIWGYDFDGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEESL
What is the function of this protein?
Member of the two-component regulatory system VanS/VanR.  Activates the transcription of vanH, vanA and vanX in response to vancomycin which results in vancomycin resistance.
What are the official names of this protein?
Regulatory protein VanRB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y666_XANAC
Sequence: MDISTDNPDHGFQFPGTFELSAMGTAERGLETELPRLLAATGVELLQESVSWKHSSSGKYVSVKIGFRAQSREQFEAAHQALRDHPEVKWTL
What are the official names of this protein?
UPF0250 protein XAC0666.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: DAPA_ECOSM
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENE_STAA1
Sequence: MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELRGFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQKILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNGYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: CLPX_SALG2
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MURB_DESRM
Sequence: MIYTSLAGELQSLVKGSIQINEPMRKHTTWKIGGKADLFLNPSDKEDIRQAVEFAREKAIPITVIGNGSNLLVKDGGIRGLVIKVGRGMAKITIEGTSIKAGAGALLPELAVFACKNSLGGFGFAAGIPGSLGGAIVMNAGAMNGCVSDVLQSIVVLNERNQFEVLTKDHLNFAYRTSNLQSRGLICVETCWQGYAKDQWLIEQETKEYLAKRKAAQPQGFPNAGSVFKNPEGDFAGRLIEGCGGKGLRVGDAEVSSKHANWILNLGRATAQDVLILIDHLKQMVQERFGVLLQLEVKVLGED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C80_RAT
Sequence: MAYRSCVVGFSSHSGCEVTPAGSSQPGTSGWGSCGLPGPGFSSRSLTSCRPAGVIPKVTVNPSLLVPLDLKVDPAVQQQKNQEKEEMKVLNDKFASLIGKVQALEQRNQLLETRWGFLQGQGSATFDLSHHYETFQGRLQEELRKVSQERGQLEASLLQVLEKVEEFRVRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQGFVELMRTVYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAARSAEFGNSLQSSRCEIADLNVRIQKLRSQIVSVKSHCLKLEENIKVAEEQGELAFQDAKDKMAQLEAALQKAKQDMARQLREYQDLMNTKLALDIEIATYHKLMEGEESRMDLPSTTVVSAVQSRCRTTASKSGLSKTPSRKKKNRGGPVIKITEMSEKYLSQESEASE
What are the official names of this protein?
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RISB_SALSV
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RUVC_NITSB
Sequence: MNILGIDPGSRNLGYAIVELNNSHMKLIEAGLVKIKPSEFQYQLSQMIEGLDMVFSSHSVDEVAMEDIFYAYNPQTVLKLAQFRGALALRIIQLHGNFSAYTPLQVKKALTGKAKASKEQVAFMVKKILGIKKEVKPLDITDAMAVAITHAQRLRLKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RF1_RICRO
Sequence: MRFSDNLAKILDKYENLGNKLSSGIMGDEFVKASKEYAELEDVVAKIKEYNKAKSELEEANNFKLEVGLDNATLEMIEDEIYTLENSLPKLERAVKIALLPKDDADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAELKGWRFEILAISDTGIGGYKEASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDIKIEDKDLRIDTYRASGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARIYEEERRKKEQARADSRRGQVGSGDRSERIRTYNFPQGRVSDHRIHLTLYKIDEVVKNGQLDEFVEALIADDEAKKLLEI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PELPB
Sequence: MKRVNVIQAKAFLKVIALLVPLLLNANGPAFALTEQASTPPHDSVASVSAPTAEAAVAAHAHGEEKAGDVIMHHILDNDVFSFEPFGEVHLPKIPPIAGVDISITKHVVMLWVVSAILLILFSLVGSKYKKMTARQAPTGLVNAMEALVEFIRIDVAKANIGVGYEKYLNYLLTVFFFVLLCNLLGLVPYGATATGNINVTLTLATFTFFITQVAALKAHGIKGYLAHLTGGTHPALWIIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILQSYIVAVVMSVPFSIFIYLLELFVAFLQAFIFTMLSSLFIGLASAHEGHEEHEAGVAHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD_FRATM
Sequence: MRDNLFIYLQYLLPHTLTSRLVSKLADSENKIIKNHLIRLAIKKFNINLVEAKETDISKYKSFNDFFIRELKDDLRPISNDKNVISSPADGVLSQFGTITDNSLIQAKGKLFSLESLIASSSTTSFTKFATIYLSPKDYHRVHMPIDGKLTKMVYIPGKLFSVNKITTSKVDNLFAKNERLICYFDTIIGEIAVIFVGALLVAGIETVWHGKIAPNYYKDIQTWDYNSAKFNIKFNKGDILGWFNFGSTVIILTSGNNVSFKFEENKNNIKIQVNQDLALITE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HARA_PYRHO
Sequence: MGELPIAPVDRLIRKAGAERVSEQAAKVLAEYLEEYAIEIAKKAVEFARHAGRKTVKVEDIKLAIKS
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.  Increases the resistance of DNA to thermal denaturation (By similarity).
What are the official names of this protein?
Archaeal histone A, Archaeal histone A1.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: GAL1_YERPN
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRDDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIIALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXB_STAAS
Sequence: MGGYKGIKADGGKVDQAKQLAAKTAKDIEACQKQTQQLAEYIEGSDWEGQFANKVKDVLLIMAKFQEELVQPIADHQKAIDNLSQNLAKYDTLSIKQGLDRVNP
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxB is required for EsxA synthesis as well as secretion (By similarity).  Mediates together with EsxA the release of S. aureus from the host cell.  Inhibits also host cytokine production and thus modulates dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein B, Ess extracellular protein B.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: GLMU_STRP1
Sequence: MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAISPEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILRDFNESLGVNDRVALAIAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAKRLAHHPSRSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_TREDE
Sequence: MDIKASDVKELRDKTGAGMMECKKALQHCNGDAKEAEKYLKEKGLAAVEKRADRVTSEGIIVIKSDHKKAVMLEMTCETDFVAKNADFIAVGEDIAKTAFDKDISEVTPELNDKLLDLATRVRENMNLTRLINVKAGADEYLSRYIHSDKKTGVIIVLKSDKPEIFEKTEVQEFAYDCCLHAAAFMPLYVKKEDVDAAYIKEQEEIFKGQVAELNKPDNVKEGIVKGKISKHLSEICFLEQAFVKDDKLSVSKKMAEVGKEAGGSLSLSKLVIFQLGLGM
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_VIBCH
Sequence: MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCAEMAKEYGLKNLEVMVKGPGPGRESTVRALNAAGFRITNIVDATPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PURR_LACLM
Sequence: MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETFPGSLGGVRFTPYITDERSLEMSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQIIAHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRDPKVTEGATLNVNYMSGSSSRVENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERLIDDYKSILKVDRIDIANRSIDVQLGNIFNDK
What is the function of this protein?
Controls the transcription of the pur operon for purine biosynthetic genes.
What are the official names of this protein?
Pur operon repressor.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: RLMN_SINMW
Sequence: MSMAATETLNRTDIAKAPQVRLAAQPEKPSLIGLLREDMAKLLVEKGVPERQVKMRVSQVWHWLYVRGVSDFNEMSNVSKDMREMLSAHFTIARPEIVEEQVSGDGTRKWLLRFPPRGAGRPVEIETVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTAEEILAQLLLARDRLGDFPDRDTPQGAIVPAEGRKITNVVMMGMGEPLYNFENVKTALLIASDGDGLSLSKRRITLSTSGIVPEIYRTGEEIGVMLAISLHAVRDDLRDMLVPINKKYPLKELMEACRAYPGLSNARRITFEYVMLKDVNDSLEDAKELVKLLKGIPAKINLIPFNPWPGTNYQCSDWEQIEKFADFINQAGYASPIRTPRGRDILAACGQLKSDSERMRKVDRLAFEAMMIANHGED
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_STRPM
Sequence: MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: GATA_GEODF
Sequence: MELFELTIHELHDKLKKKEVSSVEATESMLARIEAVEPKVNAFITVTADQALKDAAEADKRIADGDMDKLTGIPVALKDIFLTKGVRTTCASRILENFIPPYDATSVARLKARGAVLVGKLNQDEFAMGSSTESSYFGKTSNPWNLECIPGGSSGGSAAAIAAQQATATLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPVTRDVTDCAIMLEAVAGYDAKDSTSVDLPVPEYTKALTGQVKGLKIGLPREYFIEGLDPDVQKAMDEAIATYRQMGAEFQEVSLPHTDYAVATYYLVATAEASSNLARYDGARFGHRSHEAQSLLDMYRKSRAEGFGEEVKRRIMLGTYALSSGYYDAYYLKAQKVRTLIMHDFIKAFEQVDVLLTPVAPTPAFRIGEKTSDPLQMYLSDIFTIPVNLAGTCGISVPAGLSRAGLPIGLQLIGKPFGEENILRAAHAFEQNTDWHKRRAAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CYSD1_ARATH
Sequence: MEEDRCSIKDDATQLIGNTPMVYLNNIVDGCVARIAAKLEMMEPCSSVKERIAYGMIKDAEDKGLITPGKSTLIEATSGNTGIGLAFIGAAKGYKVVLTMPSSMSLERKIILLALGAEVHLTDPSKGVQGIIDKAEEICSKNPDSIMLEQFKNPSNPQTHYRTTGPEIWRDSAGEVDILVAGVGTGGTLSGSGRFLKEKNKDFKVYGVEPTESAVISGGKPGTHLIQGIGAGLIPDNLDFNVLDEVIQVTSVEAIETAKLLALKEGLLVGISSGAAAAAAIKVAKRPENAGKLIVVIFPSGGERYLSTSLFESVRHEAENLPIQ
What is the function of this protein?
Acts as a cysteine synthase.  The cysteine synthesis reaction is more efficient than the cyanoalanine synthase activity.
What are the official names of this protein?
Bifunctional L-3-cyanoalanine synthase/cysteine synthase D1, Beta-substituted Ala synthase 4;1, ARAth-Bsas4;1, Cysteine synthase D1, AtcysD1, O-acetylserine (thiol)-lyase 3.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_MACCJ
Sequence: MHIVVVSVNHKTADVSLREKLTFSESSIQQALSALINQKSILEGVILSTCNRTEIYAVTDQVHTGRYYVKSFMSEWFDVDIETIKSATDVKVGNEAIHHLFKVITGLDSIVLGETQILGQIRDSFLLAQSEGTTGTVFNKLFKDAITLAKRAHAETDISSKAVSVSYAAVELSKKILGKLENKKILIVGAGEMAELALQNLVGSGATDITVINRTAEKAKSLADQYGGRQVSLQELQCALIESDIVISSTSSQEFIITKPMMQDIMKLRKNKSLVLIDIAVPRDIDPEVNDIDLIFNYDVDDLKGLVDANLAERERAAQVIYTMIDKQVISFVDWINMLGVVPVITALREKALRIQATTMDSIDRKMPNLSERDRKVISKHMKSIINQILKDPISQAKEVSGSENRAEELQFFQEIFNITNEVESIKNNEPEVRRSKNSFVFNPEQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HV343_HUMAN
Sequence: MEFGLSWVFLVAILKGVQCEVQLVESGGVVVQPGGSLRLSCAASGFTFDDYTMHWVRQAPGKGLEWVSLISWDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKD
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-43.
What are the subcellular locations of this protein?
Secreted. Cell membrane.