PharMolix/UniProtQA huggingface dataset:
Protein: HTPG_NITEU
Sequence: MQTAENIEHLNFQAEANQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDAALYESDPDLKIRIAYDKEARTITIIDNGIGMSRQEVINNIGTIAKSGTREFFDSLTGDQAKDANLIGQFGVGFYSAFIVADKVTLTTRRAGLTIEHGVRWESGGEGEYTLETVEKPDRGTEIVLHLREGEDELLSSFQLRSIIRKYSDHITLPIVMKKEVWDDESKSYRLSDEDETINQASAIWARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREHRHGLKLYVRRVFIMDDAEKLLPGYLRFVRGIIDSSDLPLNVSREILQESKDIDSIRAGSVKKVLGLIEDLAMSDKSEDQEKFKTFWREFGQVLKEGIAEDYSNRERIAKLLRFTSTHDEREEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLCDRIDEWLVANLNEYTGKSLQSIAKGNLDLGKLEDEEEKKEHEKEAGDFQELTNKMKEVLGEQVKDVRITYRLTESPACLVADTHDVSGNLGRLLKSAGQKVPDSKPFLEINPHHPMIQRLKYEEAKFADWSHILFDQALLAEGGQLEDPAGFVKRLNDLLLQNILSGK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_MYCBP
Sequence: MREYDIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTLREAVLYLTGMNQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLAVTFRFGEEVTAVDVGSAGTVTTLASGKQIPAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDRFQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYVGATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATEMVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAALDVMNKMRALNQFRR
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_ALCBS
Sequence: MPEPLVTVQSVSVTLGGNAVLSDVSLSLAPGRITTLIGPNGAGKSTLARLVLGLVQPDSNHGTVIRRKGLRVGYMPQHIKIDDSLPLTVDRFLWLAAPGPTASRRAALERAGVAHLRRRGVQQLSGGEMQRVLLARALLRKPDLLVLDEPAQGVDVAGQNALYGLLKTVRDELGCAILLISHDLHLVMAATDEVICLQRHVCCSGSPESVSRDPAYHELFGPGAGTPNLALYTHDHDHDHDLHGNATHSHDHNGPCNHD
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DYR10_ECOLX
Sequence: MNISLIFANELITRAFGNQGKLPWQFIKEDMQFFQKTTENSVVVMGLNTWRSLPKMKKLGRDFIVISSTITEHEVLNNNIQIFKSFESFLEAFRDTTKPINVIGGVGLLSEAIEHASTVYMSSIHMVKPVHADVYVPVELMNKLYSDFKYPENILWVGDPIDSVYSLSIDKFVRPASLVGVPNDINT
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase type A10, Dihydrofolate reductase type X, DHFRX.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: SVBP_RAT
Sequence: MDPPARKEKSKVKEPAFRVEKAKQKSAQQELKQRQRAEIYALNRVMTELEQQQFDEFCKQMQPPGE
What is the function of this protein?
Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin.  Also required to enhance the solubility and secretion of VASH1 and VASH2.  Plays a role in axon and excitatory synapse formation (PubMed:30607023).
What are the official names of this protein?
Small vasohibin-binding protein, Coiled coil domain-containing protein 23.
What is the protein family that this protein belongs to?
Belongs to the SVBP family.
Protein: UBIB_ENT38
Sequence: MTPGEIRRLYFIVRTFLSYGLDELIPKMRITLPLRIWRRMLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDRVAPFDGARAKQQIEEAMGNIPVETWFDDFDIKPLASASIAQVHTARLKENGKEIVIKVIRPDILPVIRADMKLIYRLARWVPRLLPDGRRLRPMEVVREYEKTLIDELNLLRESANAIQLRRNFENSPMLYVPEVYSDYCSQNMMVMERIYGIPVSDIVALENQGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPEDPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLSEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGLPALVRSFKEKAPFWIEKMPEIPELIYDSLRHSKNLQHSMDKITRELQSNRVRQGQSRYLFGIGATLLLSGTLLLINRPDWQMMPAWLMAGGLVVWLIGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_BART1
Sequence: MRHSKSGRKLNRTASHRKAMFANMATSLIEHEQIVTTLPKAKEIRPIVEKLVTLGKRGGLHARRQAIAALRDTGKVAKLFDTLAPRYASRNGGYLRIMKAGFRTGDNAPMAVIEFVDRDVEAKGAGDRARIEALENEKGTTS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: FDL47_ARATH
Sequence: MSNRGDRISSLPDELLCQILSNLPTKNAVTTSILSTRWRSIWLSTPVLDIDIDAFDDATTFVSFASRFLEFSKDSCLHKFKLSVERDDVDMCTIMPWIQDAVNRRIQHLEVDCRFSFHFEAVYLTLYLSETLVSLRLHFVTLHRYEFVSLPNLKVMHLEENIYYCLETLENFISSCPVLEDLTVVRIVDIITEKILRVRSRSLNSLKLVLDSSNGWFIDDIDEWKVIIDAPRLAYLSLKDDQSASFVISNLGSSAKADIKVSFNVNDIWDLPVTFERSNVGKLLTGLSSIRDLTISGTTLMIICHYLKHEPMPQFCNMVRLNARFYDCDLEMLPCVLESCPNLKSLVLGLLSSAETEQQSRVSSVPPCFLSSLEFVEIRSRLCRKRYVMKVARYFAKNSVMLKKFVYVGRVSIQEEDLLALLWRYSICEIEVRGLRR
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At5g22700.
Protein: FOXN3_XENLA
Sequence: MGPVMPPSKKPEGTGISVSSQCYRSSTLSNPLQDDDDLDFPPPPVKIHKEKGGMEDEELTNLNWLHENKNLLKSFGDTVLRSVSPVQDIDDDTPPSPAQSDMPYDAKQNPNCKPPYSFSCLIFMAVEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKDRSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPYSHVFNTPPTSPQAYQSTSVPPLWPGSTFFKKNGALLQDPDIDAASAMMLLNSAHELQAGFSPGVIQNGARVLNRGIFPGVRPLPINPIGAMAASVRNGIANCRTRMESEPSCGSPLVSSDPKDDHNYSSAKSANKRSSSPSDSISSSADDHYEFAAKVCREGSDISFQSHESFSETEEEDKKQIKKELKEPLVESGYSSQHKKKQHLLKLRRIPSDALPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKDKETTKN
What is the function of this protein?
Acts as a transcriptional repressor.  May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity).
What are the official names of this protein?
Forkhead box protein N3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCRK8_ARATH
Sequence: MILKSQANKLKFTKQAKVFHYGSISLITEPCRSAHMKATEEAKEAGALLSYDPNLREPLWPSPEEARTQIMSIWDKADIIKVSDVELEFLTRNKTIDDETAMSLWHPNLKLLLVTLGEKGCRYYTKDFHGSVETFHVDAVDTTGAGDSFVGALLNQIVDDQSVLEEEERLRKVLRIANACGAITTTKKGAIPALPTDCEALSFLKRQVEQ
What is the function of this protein?
May play an important role in maintaining the flux of carbon towards starch formation.
What are the official names of this protein?
Putative fructokinase-8.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: GPMI_METH1
Sequence: MKKIILTIIDGLGLRKERQGNAYLQAKHPCFDYLFSMCPNSVLQASGQYVGLPEGQIGNSEVGHLNIGAGRVVYTGLSLINKAIENNTFKDNEILNDVIDKTIKNNTTLHVMGLLSNGGVHSLDLHLFEILKLAHSKGLKNVSVHVFGDGRDVKPQSIKNSLETLKDLCQKFGYKISSISGRFYAMDRDSIFSRNQEAYDAILGQSKNVIENIDDYIESQYKKGIFDEFFEPAQLKDGVFVKNGDSIIFFNFRPDRARQLSHMFIGSNLYTYKPKNQVQIDNFVSLMKYEGINSKIAFKEMEVVNPLGKVLESNDIKQLRLAETQKYAHVTFFFDGGVDIEYKNENRILVDSLKVDSFADYPHMSAKEITDSLLNNIEKNDFIIMNYANPDMVGHTGNLNATIEAIEFLDSQFQRILEYVSLNHENVTWFITADHGNAEITEDENNKPATKHTTSPVMFICTDKNVNLGNGSLCDVAPTILDYLKINKPKEMTGKSLLK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: EGLN_HUMAN
Sequence: MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
What is the function of this protein?
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529).  Required for normal structure and integrity of adult vasculature (PubMed:7894484).  Regulates the migration of vascular endothelial cells (PubMed:17540773).  Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity).  May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity).  May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830).  Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410, PubMed:21737454, PubMed:22347366, PubMed:23300529).  Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529).
What are the official names of this protein?
Endoglin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPF2_PAUCH
Sequence: MTSWLLLAEAGVPEGGLFDLDATLPLMAIQVVFLTFILNAIFFRPIGRTVEERENYVASSRADAKQKLAQVERLEANLTEQLRGARKQSQTVIAEAEEEVNRLYQEALRMAQAEANNIRESSRREIEIQKAAAIKSLQGDVDRLSNLIVDRLLASR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', organellar chromatophore, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Single-pass membrane protein.
Protein: PHO87_YEAST
Sequence: MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGDLNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAIDGNNINEETIELDELSPQGKTTSFNKNFIRKKFFESRSSSVSSEGKTLFSSYDTFVTNLSDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGTSETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIKSQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFKDTYIFQHETLSSLNSKIAQLIEFYAVLMGQPGNVDSCKQELKSYLHDHIVWERSNTWKDMLGLSSQNNDIITIEDEAEKLMQEKLQIEYFKYPLPKPINLKFTKIENLAVPKLFFGKRAMKIGFIIIVTGVLLGVKTFNDPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRVLKDDDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVALSADIGGMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIGKTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFGTGLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFPNVTAISMTDKKGNRWLTVGAFISRGVPASLLAFVCVITLGYGISSSVLKGST
What is the function of this protein?
Involved in the uptake of inorganic phosphate.
What are the official names of this protein?
Inorganic phosphate transporter PHO87.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NOP12_YEAST
Sequence: MSSAIDNLFGNIDEKKIESSVDKLFSSSCGPINKLEVKSKTRTVLPDSKKRERAAEADQEEKEASKPDVSDEQTEEVALPKVKKAKKSKRNDEDEDLEARYYAKLLNEEAEAEDDKPTVTKTDETSVPLTSAAKKVDFKEDELEKAERTVFIGNILSTVITSKKVYKEFKKLFGTNPIAETEESGNEKEEESSKKSDNNEFAIESIRFRSISFDEALPRKVAFVQQKFHKSRDTINAYIVYKNKSAVRKICSNLNAVVFQDHHLRVDSVAHPAPHDKKRSIFVGNLDFEEIEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDLQSVNKALLLNEKPMKSQKQEDENTKKPTKKARKLRVSRCKNMKKGTTIGTGLDRNGLTDSQRTRAGRAKKILGKADRATLGQEITIEGLRAKKGEGSTHLKKKKQRSATGRVTKRSIAFKKAQAEKSKK
What is the function of this protein?
Involved in pre-25S rRNA processing.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RPOC2_SYNY3
Sequence: MTFYNYTIDKGRLKKLIALAYRRYGSARCSQLADELKELGFRFATKAGVSISVDDLTIPPEKKQMLEAAEKEIRTTEERYARGEITEVERFQKVIDTWNGTSEELKDQVVVNFRKTDPLNSVYMMAFSGARGNMSQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIVREQDCGTERSLRVTAMTDGDQVKISLADRLFGRLLAKDVVGPDGEIIAKRNDEIDEALANRIAAVTDEVYVRSPLTCEAARSVCQNCYGWSLAHGHKVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVARQEKAPEDGTVKWGKGLSTRKVRTRHGEDAEQVEIAGDLIWKGEGKKAATQTYSLTPGSLLFVQDGQTVTAGQLMTEISLSKTQRSTERATKDVAGDLAGEVLFDRLVPEEKTDRQGNTTRIAQRGGLVWILSGEVYNLPPGAEPVVKNDEQVEVGSIMAETKLVTNDGGVVRLVSNREIEIITASVLLDQAQVKLESSGGREQYVIYTADKQRFLLKAAPGTKVQNHSIVAELIDDRYRTTTGGMIRYAGVEVAKGGRKQGYEVTKGGTLLWIPEETHEINKDISLLIVEDGQYVEAGTEVVKDIFCQSSGIVEVVQKNDILREIIIKPGDFYQDVDPGSVKIESGQLLQPGQDVFPGVTVSTLSQAEWIESPEGNGLLLRPVEEYKVFDEPAAPSQGSQNEEGGRQIELRSVQRLFYKDGDRVKSVEGAPLLSTQLVLEIYGSGNEGISHLSADIELQDDEEEDCQRLQLVILESLVLRRDQESDPLGGASKTRLLVQDGDQIPPGAVVARTEIQCKEAGTVRGIKEGQESIRRVLLERAADRLVVDLPSAPEVKPGQLLVAGQELVPGVKLEESGKVLEINGKGDNYQLVLRRARPYRVSPGAVLHIEDGDLVQRGDNLVLLVFERAKTGDIVQGLPRIEELLEARKPKEACVLARAPGVCQVEYLEDESVDIKVVEDDGTVSEYPLLPGQNAMVTDGQRIDVGHALTDGYNNPHEILDVFFSYYVDKDGCYQAALRGLQAAQKFLVNEVQTVYQSQGVDISDKHIEVIVRQMTAKVRIDDGGDTTMLPGELVELRQVEQVNEAMGITGSAPARYTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSSHEEVLGLIETQDDIQGYMIEPIELPTTKKKASATKVKTKKVEADDDLLDDTRARAYAGTQLSQDDEEFEETYDTDEDDFDMDDDDDFGDDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: RS5_MICAN
Sequence: MAKRRKGNREKEKETTWQERVIQIRRVSKVVKGGKKLSFRAIVVVGNENGQVGVGVGKAGDVIGAVRKGVADGKKQLIEVSLTKASSITHLTRGASGGAQVIMRPAAPGTGVIAGGAVRTVLELAGVKNILAKQLGSDNPLNNARAAVNALETLRTFSEVAKDRGVSIEHLYT
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CYOE_ECOUT
Sequence: MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLVGVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLWFGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDSGAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAVATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALSVMMSVDFMVPDSHTLLAAVW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRC_ERYLH
Sequence: MTETLTIRRPDDWHLHFRDGAMMRGVVPYTARQFARAIVMPNLTPPVTTTALGAAYRERILAAVPEGVDFRPLMTAYLTDETDADDLIDGYTHGVFTAAKLYPANATTNSASGVTDVEALYPVFERMAAAGMVLCIHGEVTDADVDVFDREKEFIERTMAPLHAAIPALKIAFEHITTSDAVDFVVGANDNIGATITPQHLHINRNAMLVGGIQPHNYCLPVAKRETHRLALRQAATSGPPKFFLGTDSAPHEKHTKESACGCAGIFGAPYALESYLAVFEEEDALDKFEAFASLNGPAFYGLPVNDETITLERVPHNVPDSLETEGGKVVPFHAGQELNWRLK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: LIS1B_DANRE
Sequence: MVLSQRQRDELNRAIADYLRSNGYEEAYSTFKKEAELDVNDELDKKFAGLLEKKWTSVIRLQKKVMELESKLNEAKEEITLGGPVGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSLMVSASEDATIKVWDYEAGDFERTLKGHTDSVQDISFDQTGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTMKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLLASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESAHPTISEATGSENKKSGKPGPFLLSGSRDKTIKMWDISTGMCLMTLVGHDNWVRGVLFHPGGRFVVSCADDKTLRIWDYKNKRCMKTLSAHEHFVTSLDFHKASPYVVTGSVDQTVKVWECR
What is the function of this protein?
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in the PAF inactivation.  Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner (By similarity).  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome.  May be required for proliferation of neuronal precursors and neuronal migration (By similarity).  Involved in the positioning of nuclei in photoreceptor cells.
What are the official names of this protein?
Lissencephaly-1 homolog B, Platelet-activating factor acetylhydrolase IB subunit alpha b.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: RS19_ARTS2
Sequence: MPRSLKKGPFVDQHLFVKVDRENEKGTKNVIKTWSRRSMIIPDMLGHTIAVHDGRKHIPVFVTESMVGHKLGEFAPTRTFRGHVKDDRKGKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HSLV_YERPE
Sequence: MTTIVSVRRDGHVVIGGDGQVTLGNTVMKGNAKKVRRLYNNKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPEDDLIAIGSGGPYAQSAARALLENTELGARDIVEKSLSIAGDICIYTNRFQTIEELTY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_RICTY
Sequence: MSSINKKELKKFEKISHNWWNKDGEFGILHRINHIRIEYIIEKIKLHYNDISKLQILDVGCGGGLIAAPLASQGFNVTAIDALKSNIETATIYAQKNDLKINYLQTTIEELENDKLYDVVICLEVIEHVENVQQFILNLVQHIKPNGIAIISTINRTKKAYLFGIIVAEYILGWVPKNTHDYSKFLKPSEIYEILTDTNIEIKELKGLVFNLARNEWKLSNDIDVNYFMYLGKKINSLSNAINSIP
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y1697_HAEI8
Sequence: MFDINLTHEQQQKAVEQIQELMAKGISSGEAIQIVAKALREIHKNDKKTPDN
What are the official names of this protein?
UPF0181 protein NTHI1697.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: SYH_PROMT
Sequence: MTNLKNLRGMVDLLPAQSQGWQKVESIALEHFSRAGLQEIRTPIIEQTELFSRGIGENTDVVGKEMYSFDDRGGRSCTLRPEGTASVARSIVQHGLLNKGPQRLWYRGPMFRYERPQAGRQRQFHQIGVEFVGLASVISDAEVISIAWNFLKDVGLNELTLEINSLGSNEDRNIFKEELKDWLNQRFDLLDEDSQKRINVNPLRILDSKNNSTKELLSEAPSLIDFLSNESKTRFDYLQELLVNLKIPYEINYNLVRGLDYYSHTAFEITSDHLGSQATVCGGGRYDGLISELGGPQAPSIGWAIGMERLIILAGDKILQSKSPDVYVIHKGKKAEQLALEITCQLRSSNLIIELDYSGSSFSKQFKRADKSRAKWALVIGEDEVSKGQLLMKKLRDKQKDEESREYIFSKSDLDQLIKKLIAEKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A37C_DROME
Sequence: MQCFKLASRRSLYNARVLQADNIGDKQRSPDLEAARQNTQIVVVGAGLAGLSAAQHLLSHGFRRTVILEATDRYGGRINTQRFGDTYCELGAKWVKIDGSQDSMYELLRNTEGLGKQIKQPDRATYLQDGSRINPAMVELIDTLFRQLCRGFKVSERVKTGGDLHSLDNVMNYFRTESDRIIGVSFQHPKDQLAAREIFQSLFKEFGSILGCCLEYVNIEHITKCPVQQEQRPLYVPTGLDNVVDDLIQNMDKAQLQTGKPVGQIQWTPAPMKSVGCLDGSLYNADHIICTLPLGVLKSFAGVLFRPTLPLDKMLAIRNLGFGNPLKIYLSYKKPIGRWLKGSLRPLGTLLNPSVEQQPERNWTQQVVEISQVPSSQHVLEVHVGGGYYEEIEKLPDEELLEQITGLLRRCVSSHLVPYPQELLRSNWSTSACYLGGRPYFSTNSSARDVQRLAAPLGEKSPGLLFAGDATSLRGFGTIDAARSSGIREAQRIIDYYLKSVHCG
What is the function of this protein?
Has a non-vital function.
What are the official names of this protein?
Protein anon-37Cs.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGP_PIG
Sequence: MKSLLLLSVLAALAVAALCYESHESLESYEINPFLNRRNANTFISPQQRWRAKAQERIRELNKPPYELNREACDDYKLCERYAMVYGYNAAYNRYFRQRPGAK
What is the function of this protein?
Associates with the organic matrix of bone and cartilage.  Thought to act as an inhibitor of bone formation.
What are the official names of this protein?
Matrix Gla protein, MGP.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.