PharMolix/UniProtQA huggingface dataset:
Protein: SAPC2_HUMAN
Sequence: MAGAAMAERGRVPPPAPAPSTEGLPRAFLQSLRTLFDILDDRRRGCVHLREIESRWQGTDARELPRGVLEGLRQVAPASGYLTFERFVAGLRTSLLSADGGPRDPTRAPARPGDQPPPPPQRLVFAPADEPRTVLERKPLPLGVRAPLAGPSAAARSPEQLCAPAEAAPCPAEPERSQSAALEPSSSADAGAVACRALEADSGDARRAPRARGERRRHTIASGVDCGLLKQMKELEQEKEVLLQGLEMMARGRDWYQQQLQRVQERQRRLGQSRASADFGAAGSPRPLGRLLPKVQEVARCLGELLAAACASRALPPSSSGPPCPALTSTSPPVWQQQTILMLKEQNRLLTQEVTEKSERITQLEQEKSALIKQLFEARALSQQDGGPLDSTFI
What is the function of this protein?
Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity).  Negatively regulates the mitotic apical cortex localization of GPSM2 (PubMed:26766442).  Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:23576022, PubMed:23704824).
What are the official names of this protein?
Suppressor APC domain-containing protein 2, Tumor specificity and mitosis phase-dependent expression protein, TS/MDEP, p42.3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cell cortex. Apical cell membrane. Cell junction, tight junction. Note=Localized at the apical cortical region during the M phase. In horizontally retinal progenitor dividing cells, localized at the pole cortical region from prophase to telophase cells. In vertically retinal progenitor dividing cells, not detected at the pole cortical region at any stage of mitosis.
Protein: BPHF_RHOJR
Sequence: MQSPINSFKKALAEGRTQIGFWLALGDAYSAEVCAGAGFDWLLIDGEHAPQDLRSVLAQLQVIGAYRDCHAAVRVPSADTTVIKQYLDLGAQSLLVPMVDTADEAAAVVRACRYPPGGIRGVGGARASRWGRYPRYLHEADEQVCVVVQAETALALSNLEAIAEVDGIDGVFIGTADLAASLGFPGNPAHPEVQDAILDALQRVRAAGKAPGVLTPVEDLAQKYLAHGAVFVAVGIDTHLLAKQTSALAARFAQVAYS
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-oxovalerate to pyruvate and acetaldehyde.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: UVRC_PSEPK
Sequence: MSQVFDASAFLATCSGRPGVYRMFDGEARLLYVGKAKNLKKRLASYFRKTGLAPKTAALVARIAQVETTITANETEALLLEQNLIKEWRPPYNILLRDDKSYPYVFLSDGEFPRLGIHRGAKKAKGRYFGPYPSAGAIRESLSLLQKAFSVRQCEDSYYANRTRPCLQYQIKRCKGPCTDLVTAEEYAEDVRHSVMFLEGRSQQLGNELNAEMEKAAMALDFEKAAELRDQIALLRRVQDQQYIEGGSGDVDVIAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVAEVMAAFLSQYYLGNAERELPGELIVNVVHEDFNAITEALHTLRGRELTISHRVRGTRARWQQLAVTNAEQALNARLANRQHMAARFEALAEVLGLDEVPQRLECYDISHSSGEATVASCVVFGPEGPIKSDYRRFNIEDVTAGDDYAAMHQALTRRYGRIKDGEGKLPDVLLVDGGKGQLNMARDVMQELGFTDLTLLGVAKGVTRKAGFETLYLNDVHHEFTLKGDSSALHLIQQIRDEAHRFAITGHRARRGKARRVSSLEDVAGVGPKRRRDLLKHFGGLQELNRASIDEIAKAPGISKKLAESIYASLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_RICPR
Sequence: MTRAKSGKISKKRHKKILKLAKGYRGRANNCFRVAIEKVEKGLQYAYRDRRNRKRDFRGLWIQRINAAVREHGLIYSQFMGALKKAGINIDRKVLAELAVNNNDGFASIVQQSKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RNC_HELAH
Sequence: MKNKNNKLADCPYITLEKALGYSFKDKHLLEQALTHKSCKLALNNERLEFLGDAVLGLVIGELLYHKFYQYDEGKLSKLRASIVSAQGFTKLARAISLQDYLRVSSSEETSKGREKPSILSSAFEALMAGVYLEAGLDKVRKIMQNLLNRAYKRLDLEHLSVDYKTALQELTQAQFCVIPTYQLLKEKGPAHHKEFEMVLYIQNQMYATAKGKSKKEAEQQCAYQALQKLKGIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP4_RAT
Sequence: MSDGAAARRWGKCGPPCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSSV
What is the function of this protein?
Forms a water-specific channel (PubMed:7528931, PubMed:7509789, PubMed:19800950).  Plays an important role in brain water homeostasis and in glymphatic solute transport.  Required for a normal rate of water exchange across the blood brain interface.  Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways.  Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.  Plays a redundant role in urinary water homeostasis and urinary concentrating ability (By similarity).
What are the official names of this protein?
Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Note=Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane (PubMed:19800950). Detected on brain astrocyte processes and astrocyte endfeet close to capillaries (PubMed:29055082).
Protein: DBP2_CHATD
Sequence: MSSYGGGYSGGGGGYSNNYDRNGGYSNGYSGSNGYSGGGGGYGSHGSRSYGGGGYGGGYGGGDRGGDRMAGLGSGLQKPNWDLATLPKFEKSFYKEHPNVTARSMAEVEKFRRDHNITVSGRDVPKPVETFDEAGFPRYVMDEVKAQGFPAPTAIQAQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQQEINKFGKSSRIRNTCIYGGVPKGPQIRDLQRGVEVCIATPGRLIDMLESGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIISQIRPDRQTLMWSATWPKEVRNLAADFLTDFIQVNIGSLDLAANHRITQIVEVISESEKRDRLIKHLEKIMDSRDTQNKCLIFVGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLDQFKTGKSPIMVATDVASRGIDVRNITHVINYDYPNNSEDYIHRIGRTGRAGAKGTAITFFTTENAKQARDLVSVLQEAKQHVDPRLLEMARYSGGGGSSRYGGYRGRGGGGYRGGHRSAAHSGANAVPVANRRW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
ATP-dependent RNA helicase DBP2, DEAD box protein 2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IHFB_BURP6
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALSKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKHVPHFKPGKELRERVDGRAGEPLKNDEPEDAQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PE1_ANOGA
Sequence: MKVSASLVLLLAAAVLADDRCPPQDDPEQPPVLLAHPTDCDKFLICNHGTPVVSKCPPGLLWNDSQKQCDYPAQAQCAPGVTPNTEPAPKPSPNCPPEYDPDHMVYIPHETDCGKYYICDPYGVELEQTCPSGLHWNPVVNYCDFPELAQCEE
What is the function of this protein?
Binds chitin but not cellulose.  May be involved in the spatial organization of PM.
What are the official names of this protein?
Peritrophin-1, AgAper-1, Peritrophic matrix protein 1, Peritrophin A.
Protein: MURC_CHLPM
Sequence: MELGKTKRVHIVGIGGAGMSAIAELLLKSGFGVSGSDLSSGEVTEKLAAHGATIYLGHQASQVEACDVVVYSSAVKPEDNVEIAAAMQAGIPVVKRDEMLGELMRYKSGICVAGTHGKTTTTAMVATMLIEAGESPTVMIGGISDYLKGSTVVGSGKYMVIEADEYDRAFLKLTPTIAVLNSLEAEHMDTYGTLEDLKKAFVAFANKVPFYGRVICCADWPEIRGIIGSLNRLCTTFGIDEPADVSATDIVMANGRTTFTVQAFGEVYPGVSIAVPGRHNVQNALAAFATGLELGLDPARLVHGLGCYSGMRRRFQIKYDNGRGLLVVDDYAHHPSEVKATLKAARNGWPSARIVAVFQPHLFSRTREFASEYGWALSRADMVYISSIYPSREKEEDFPGVDAGMVAGAVTKAGGKHVLYVSDSGELKRLLLEEASAAGPRGTILLFMGAGDITAMASEVARCGEKENL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SHEPA
Sequence: MSNIPAELKYASSHEWIRKEEDGSYTVGISEHAQELLGDMVFVELPEVGDDVNAGEDCAVAESVKAASDIYAPLSGEVVAVNEALEDSPELVNSDAFGDGWFFRVMPTDLAELDNLLDAEGYQAVIDDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: QUEF_STRT2
Sequence: MSQQEEMKNLTLLGSKETPYIFEYSPQVLESFDNRHADNDYFIKFNCPEFTSLCPITGQPDFASIYISYIPDQLCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVELLNPRYLEVWGKFTPRGGISIDPYYNYGRPKTKYENMAEQRLFNHDLYPENIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_YEAST
Sequence: MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVDVEGTEAVEDEIEMLIENVKEDSMACGKILAERMIADGAKKILDEINLDRIK
What is the function of this protein?
Catalyzes the tetrapolymerization of the monopyrrole porphobilinogen (PBG) into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GR33A_DROME
Sequence: MIQIMNWFSMVIGLIPLNRQQSETNFILDYAMMCIVPIFYVACYLLINLSHIIGLCLLDSCNSVCKLSSHLFMHLGAFLYLTITLLSLYRRKEFFQQFDARLNDIDAVIQKCQRVAEMDKVKVTAVKHSVAYHFTWLFLFCVFTFALYYDVRSLYLTFGNLAFIPFMVSSFPYLAGSIIQGEFIYHVSVISQRFEQINMLLEKINQEARHRHAPLTVFDIESEGKKERKTVTPITVMDGRTTTGFGNENKFAGEMKRQEGQQKNDDDDLDTSNDEDEDDFDYDNATIAENTGNTSEANLPDLFKLHDKILALSVITNGEFGPQCVPYMAACFVVSIFGIFLETKVNFIVGGKSRLLDYMTYLYVIWSFTTMMVAYIVLRLCCNANNHSKQSAMIVHEIMQKKPAFMLSNDLFYNKMKSFTLQFLHWEGFFQFNGVGLFALDYTFIFSTVSAATSYLIVLLQFDMTAILRNEGLMS
What is the function of this protein?
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.  Required for sensing all nonvolatile repulsive chemicals, including tastants, pheromones, and especially N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide.  Functions also as a pheromone receptor for a male inhibitory pheromone leading to male-male courtship suppression.
What are the official names of this protein?
Gustatory and pheromone receptor 33a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr66a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRS2_YEAST
Sequence: MNRRLLVRSISCFQPLSRITFGRPNTPFLRKYADTSTAANTNSTILRKQLLSLKPISASDSLFISCTVFNSKGNIISMSEKFPKWSFLTEHSLFPRDLRKIDNSSIDIIPTIMCKPNCIVINLLHIKALIERDKVYVFDTTNPSAAAKLSVLMYDLESKLSSTKNNSQFYEHRALESIFINVMSALETDFKLHSQICIQILNDLENEVNRLKLRHLLIKSKDLTLFYQKTLLIRDLLDELLENDDDLANMYLTVKKSPKDNFSDLEMLIETYYTQCDEYVQQSESLIQDIKSTEEIVNIILDANRNSLMLLELKVTIYTLGFTVASVLPAFYGMNLKNFIEESEWGFTSVAVFSIVSALYITKKNFNSLRSVTKMTMYPNSPANSSVYPKTSASIALTNKLKRRRKWWKSTKQRLGVLLYGSSYTNKANLSNNKINKGFSKVKKFNMENDIKNKQNRDMIWKWLIEDKKN
What is the function of this protein?
High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix (PubMed:12628916, PubMed:17827224, PubMed:20653776, PubMed:23999289).  Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.  It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes (PubMed:11544180).
What are the official names of this protein?
Magnesium transporter MRS2, mitochondrial, RNA-splicing protein MRS2.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PG162_VACCW
Sequence: MKSLNRQTVSRFKKLSVPAAIMMILSTIISGIGTFLHYKEELMPSACANGWIQYDKHCYLDTNIKMSTDNAVYQCRKLRARLPRPDTRHLRVLFSIFYKDYWVSLKKTNDKWLDINNDKDIDISKLTNFKQLNSTTDAEACYIYKSGKLVKTVCKSTQSVLCVKKFYK
What is the function of this protein?
Forms a complex with OPG162 and OPG190 to coordinate the incorporation of OPG164 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails (PubMed:23255618, PubMed:31941777).  Therefore plays an essential role in efficient cell-to-cell spread of viral particles.
What are the official names of this protein?
Protein OPG162.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG162 protein family.
Protein: IF2_HAMD5
Sequence: MTDVTVKSLAEEIKTSVDRLVQQFFDAGIKKSQTDTVTQQEKEKLLAHLNRQQGTVDNQLTLQRKTRSVLNIQVTGGKSKTVHIEVRKKRTYVNPSVTKPEAPLPEEENAQIPKITKNTFSQESLNKTSPQKSLKTKAIEKAKIESPKKERHSLKEKQKKEAQSEKARREAEASSLKRFAEEEVRRKVEEEAKRVAEQARKMAIENEAKWSELVADQIDSVDYHVTTSEHARAAEDENDAKVEGDRRSRHRGTKTTKQKKTNKLSESKTDREEARAVVRKSKRKPSALQQSFNKPVVALNRDVVIGETISVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDTGVLTVHRAPVVTIMGHVDHGKTSLLDYIRSTKVATGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAKVPVVVAVNKIDKAEADPDRVKKELIQHGIQPEEWGGDSQFIHVSAKVGTGIDDLLNAILLQAEVLELKAVKSGMANGVVIESFLDKGRGPVATVLVQEGTLNKGDIVLCGFQYGRVRAMRNELGREVISAGPSIPVEILGLSSVSSAGDAVTVVRDEKKAREVALYRQGKFREIKLARQQKSKLENMFDSLREGEISELNIVLKSDVQGSCEAIREALQKLSTDEVKIKIIGSGVGGITETDATLAAASNAIILGFNVRADAATRRLVEAENLNLRYYSVIYDLLDEVKQAMSGMLSPKYEQKIIGLAEVRDVFKSPKFGAIAGCMVVEGLIKRSSPIRVLRNNVVIYEGELESLRRFKDDVNEVRNGIECGIGVKNYDVQVNDTIEVFEIIEIKRTIS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_NEIMA
Sequence: MKNYHAPDEKGFFGEHGGLFVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPVYHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGSNAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RBFA_BURM7
Sequence: MSKKRSSPNRNVQIADQIQRDLSELIMREVKDPRIGIVTIQSVELTPDYAHAKVYFTALTGTPADTQEALNHAAGHLHNLLFKRLHIHTVPTLHFHYDQTIEKAVAMSRLIDEANATRAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CHLT3
Sequence: MKIILRKEVSSLGLQGEVVTVKDGYARNFLIPNGLAIRATEGAIKAIETEKKQRAFKIEKERKAARELADSIERISLSVCVKAGESGKLFGTVTPQMIADGLKTKGFDVDRKQITIEEPIKALGKYEVSIKLYTDVVATLKLEVEGEAVEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PKAA_STRCO
Sequence: MRPVGSKYLLEEPLGRGATGTVWRARQRETAGAEAAVAGQPGETVAIKVLKEELASDADIVMRFLRERSVLLRLTHPNIVRVRDLVVEGELLALVMDLIDGPDLHRYLRENGPLTPVAAALLTAQIADALAASHADGVVHRDLKPANVLLKQTGGEMHPMLTDFGIARLADSPGLTRTHEFVGTPAYVAPESAEGRPQTSAVDVYGAGILLYELVTGRPPFGGGSALEVLHQHLSAEPRRPSTVPDPLWTVIERCLRKNPDDRPSAENLARGLRVVAEGIGVHANSAQIGAAENVGALLAPDPAPAQVPGAPDAAYDPNGATSVLPHTSGPAGAADPTAVLPSTGAPDPTAVMPPVPPGQPGAPGQGGPEDPHPWQNQLRAARDRNEQTQVQYLDPNQDPLRRRPQRQVSRPPQQPRQAPQGPPPQQPGYGYPQQQQPQRYATPQPQQPQRYAPPPAPEPQQPRREPRPPRQRSANPMRIPGLGCLKGCLVTVVVLFVAGWLVWELSPLQEWIGTGKGYWDQLTDWFTTVTDWIGDLGGSGGG
What are the official names of this protein?
Serine/threonine-protein kinase PkaA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RS21_PSEA6
Sequence: MPIVKVRENEPFDVALRRFKRSCEKAGVLSEVRRREFFEKPTWERKRKKAAAKKRLLKKLSRENARRIRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL17_ZYMMO
Sequence: MRHRVGGRKLQRTSSHRLALFRNQSAALIKHEQIITTLAKARELRPYTEKLITLAKKGGLANRRLAHSRLLDDTQLKKLFDVLAERYKDRNGGYTRIIKAGIRASDAAQMAVIELVDRDTTAKGQDSGPVQVEEQENEEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: M2_I37A0
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVAAASIIGILHLILWILDRLFFKCIYRRLEYGLKRGPSTEGVPESMREEYRQKQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: SAMD7_MOUSE
Sequence: MTNPMMSVSSLLTSGQQKVPMVPSPFGPPIVDRDVLSSSIAPTDPSQFCVPSQFGSSGLPNANMPNPLSSHFYSGWGILPPEPIKAVTTRNEMFERHHAARAEMEMYSLYQQRRMERVNPKGLSGLGIPLFYGSSCLGGPTGFQGRSTLPASDVHLHRSTFRHLQGNPILLATRPHFTECWGQKYRLRRGAVYQKPPESDTESFKSQAEEKSSSQMPTLSYEEEEYIKDPDIEVDNQQKPRVADGKPTTVPANPHGELHTHQRKPSSLEANAWDDGKGKPSEQVYEGCDGKNGVFRPVSILPLSGTHEQVALRENCSLSDIQKWTVDDVYNFIRSLPGCSDYAQVFKDHAIDGETLPLLTEQHLRGTMGLKLGPALKIQSQVSQHVGNMFCKKLPSLPTHARQAFDQPADTSPLLDMSSWSDGLSIPGPQDLLSPKRTEQDVMRN
What is the function of this protein?
Involved in the regulation of gene expression in the retina.  It functions as a negative regulator of CRX-controlled genes.
What are the official names of this protein?
Sterile alpha motif domain-containing protein 7, SAM domain-containing protein 7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: AP2S_ASPFU
Sequence: MVLSFILVQNRQGKTRLAKWYAPYSDEEKVKLKGEVHRLVAPRDQKYQSNFVEFKRSTKIVYRRYAGLFFCVCVDATDNELAYLEAIHFFVEVLDQFFGNVCELDLVFNFYKVYAILDEVFLAGEIEETSKQVVLTRLEHLDKLE
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).
What are the official names of this protein?
AP-2 complex subunit sigma, Adaptin small chain, Clathrin assembly protein 2 sigma small chain, Sigma2-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of the plasma membrane coated vesicles.
Protein: RS4_AROAE
Sequence: MARNLDPKCRQCRREGEKLFLKAEKCFTDKCAIERRAYAPGQHGQRSGQRMSGYGVQLREKQKIRRLYGVLEAQFRKVYAEAERRRGQTGENLLQLLEGRLDSVVYRMGFGGSRAESRQLVRHNGILVNGKRVNIPSYVVRPGDVVELTEGSRGQLRVKAALEAAASRGFPEWLDVDAKAGKGTFKAYPQRAELPPTINEGLVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DHQA_NEUCR
Sequence: MSTATTTTSATTTMSVVQPRQQELLHLTSTPDITPYTRHGYLFGQKLAASMSPLLHSIVYSHLSLNWAQLRLDSPSIPLFLQLAQHPDFYGASVTMPHKVAIIPHLDHLTPECRDVGACNTLFLKTDPATGRRLYCGANTDVIGVRESFVQNVSDPARVYESRPALVIGGGGAARSAVYALHKWLGATDIYLVNRDKSEVDAVIAECTERGYGDRLVHVASVEQAEGLEGPGAIVACIPDFPPKTEKEMLVRRIVETFLMKEEKGAMLEMCYNPSPFTELGALAEHEGWQVILGTEALIWQGIEQDKYWTGRTNEELPIQQIKEVIAAKLAEASKSHTS
What are the official names of this protein?
Quinate dehydrogenase.