PharMolix/UniProtQA huggingface dataset:
Protein: UVRC_RICCK
Sequence: MTSDATGSELIKSKLVDAPECAGVYQMFDVNKQVIYVGKAKNLKKRLTNYIKLDLDNKTLRMIANTCFLEYSVTSSEVEALLLEAQLIKKFQPKFNILLKDDKSFPFIKLRLDHDFPQLLKYRGRTRTLSDGKFFGPFASATAVNTTLTELQKIFKLRSCTDNYFNSRNRPCLQYEIKRCYAPCISKINKKDYAELVIQVTAFLQGHTKELQENLSKKMEELSSHMYFEEAAEIRDRIKALSYVQLKAGISDIVKDADIMAIVEKNGHYCVEVCLYRAGQACGTIPYFPTAMGNNTKEAILKYFLLQFYQKQQLPSEIIINNEVEDKEDVIEAIKKINNITKLNIILPISGGKAKLVQNATTNALFSLEQYLKKFAKNQEIMLEIKELFDLSEIPERIEIYDNSHIQGKFAVGVMVVAGKSGFDKKEYRVFSLSSHDSITGFSTLTNNLDPVVKQQYDTNGTYNTTVGDDYDMFRQVLTRRLTRLKQEPYKLPSLMIIDGGRGHVGIVKEVMDKFKMNIPFVCMSKGPDRNAGLEQFHMVGKEVFTLDKNLPVMKYLQILRDAAHSFAIKNHRLGRSRTIKLSSLDNIKGIGKTRKKSLLHYFGSYKAVCDATIDELVKVHGISKSLAEMIFRTLHQS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_LEGFO
Sequence: MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAAILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNELKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METE_BURP1
Sequence: MTTAHILGFPRIGAQRELKFALERYWRDGASADAERALVDTGRALRAEHWRIERDAGLDCVTVGDFAWYDHVLTTLAHVGGLPRRFGFDARALTLADYFAAARGNAAQPAMEMTKWFDTNYHYLVPEYSPATTFGPGVEWLFDEVREARALGYRAKAALVGPLTLLWLGKARDGLVERLALLPRLVPAYRALLARLREAGVDWVQIDEPIFSLDLPDAWRDAARPTYEALAPGAPKLLVATYFDDASEHAALLKALPVAGLHVDLVRADAQLDAFVADYPADKVLSCGIVDGRNVWRNDLDRSLARLAPVRDALGERLWVATSCSLLHVPVDLAHEPRLDEELKTWLAFAAQKTREVAALRDALVKGRAAVAAEFDDAAAAAAARRTSARIHNPLVKRRVAALTDADARRASAYSVRAAAQRARFGLPLLPTTTIGSFPQTPEIRRARAAFKQGVLDHLGYLEAMREQVRIAIDKQLAYGLDVLVHGEAERNDMVEYFGELLWGFAITSNGWVQSYGSRCVKPPLVYGDVYLPEPMTVGWASYAQSLSAKPVKGMLTGPVTMLQWSFVRDDQPRATTALQIALALRQETLDLEKAGIGMIQIDEPALREGLPLKARERAAYLDWAVRAFGIAASGVADDTQIHTHMCYSEFGDILPSIAALDADVISIETTRSNMELLDAFETFDYPNEIGPGVYDIHSPRVPDADEIERLILLALERIPAQRLWVNPDCGLKTREWRQVDAALAAMVDAAKRVRQKVEEAAPA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RNH_PSEPW
Sequence: MSDSVELYTDGACKGNPGPGGWGVLLIYKGVEKELWGGERETTNNRMELMAAIQGLMALKRECEVVLTTDSQYVMKGINEWMVNWKKRGWKTAAKEPVKNADLWQQLDEQVNRHKVTWKWVRGHIGHPGNERADQLANRGVDEVRAKR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD3_YEAST
Sequence: MEHNLSPLQQEVLDKYKQLSLDLKALDETIKELNYSQHRQQHSQQETVSPDEILQEMRDIEVKIGLVGTLLKGSVYSLILQRKQEQESLGSNSK
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B.  Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
What are the official names of this protein?
DASH complex subunit DAD3, DUO1 and DAM1-interacting protein 3, Outer kinetochore protein DAD3.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: KUP_BURCM
Sequence: MNDTIQATDAAHAHSTHQHSMRALAIAAIGVVFGDIGTSPLYALKEAFSPAHGIPLTESSILGVISLLFWAIILVVGIKYLLFVMRADNNGEGGVLALMALSLRPLDPKTRVAGALMALGIFGACMFYGDAVITPAISVMSAVEGLEIATPHLSHLVLPITIVILIALFWIQRHGTALVGKLFGPIMVVWFIVIAALGVYHIARVPGIIAAINPYYAASFMADHLLQAYVVLGSVVLVLTGAEALYADMGHFGAKPIRLAAYGLVMPSLVLNYFGQGALLIQNPKAIENPFFLLAPEWGLLPLVVLSTVATVIASQAVISGAYSLTSQAIQLGYVPRMKVLHTSELAIGQIYVPVVNWLLLFVILCIVIGFKSSDNLAAAYGIAVTATMVITTVLACVVMVKVWNWNRLLVGAIIAVFLAIDLGFFGANLLKVAQGGWLPLGIGALLFFLLMTWYKGRHIVKERTAADGIPLEPFLQGLLAHPPHRVSGTAIYLTGNDKLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVRDDTRLSSRDAGGGLYIVKAQYGFNETPDVKAVLEEFGRSHDMTFELMDTSFFLARETVVPTHLPGMSIWRERVFAWMHQNAAKPTDFFSIPANRVVELGTKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRP54_RICTY
Sequence: MFKTLTQNLTKIFDRLVNSGILTENQIDTAMRDVRVALLESDVALPVIKGFIAEVKQKALGQEVIKSVSPGQMIIKIIHEEMINLLASSESTTKLNLNSKPPVNLLMVGLQGGGKTTASGKLALLLKNQNKKVLLVSLDTYRPAAQEQLAIIANSVNIDSLPIVQGEQPLDIVKRAISEAKIFAYDVVIYDTAGRIQIDNVMMEEALAIKKILNPTETLLVIDSMTGQDAVVTARSFSDKLEISGLILSRIDGDTKGGAALSVKYLTQKPIKFLSCGEKLTDLEEFDAERLASRILDMGDIISFVKKAASIVDREEAERTAIKLKSGKFDLNDYLKHMRSIKKMGGFGSILSMLPGSGKIIDQIDQSKLDSRIIEHQEAIILSMTLKERKNPDIINASRRKRIAAGAGMTVQKVNILLKQYKQISAVMKKASKMNPQNLFRSGISKLFS
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: DMA2_YEAST
Sequence: MYTPIPANTPAPTAPTSSMTSNSSSASNANTTSSSGINPRNRASGTPSNERARPASGISSFLNTFGIRQNSQTASSSAAPDQRLFGTTPSNSHMSVAMESIDTAPQQQEPRLHHPIQMPLSAQFHVHRNYQLPISISLTAPTTTDHQQSSAHNFEGNNVGNVQESLNQRQPNGTNNTTTSIISMAPAATTRNIVGGADGSTIVNNSQEMYKNLRHLIYAANQPNGTEILHLDLPATSAEESNNMFNVDEVTLKQRKDKHGLFSIRLTPFIDSSSTTNQGLFFEPIIRKAGPGSQLVIGRYTERVRDAISKIPEQYHPVVFKSKVVSRTHGCFKVDSQGNWYIKDVKSSSGTFLNHQRLSPASSLSKDTPLRDGDILQLGMDFRGGTEEIYRCVRMRIELNRSWKLKANSFNKEALQRLQNLQKLTTGIEEEDCSICLCKIKPCQAIFISPCAHSWHFRCVRRLVMLSYPQFVCPNCRSSCDLEASFESSDEEDESDVESEGDQLVDQLSVLMETSKDVDSHP
What is the function of this protein?
E3 ubiquitin-protein ligase which functions in cell cycle retarding in conjunction with the UBC4 and UBC13/MMS2 complex, 2 E2 ubiquitin conjugating enzymes.  Involved in nutritional control of the cell cycle.  Required for proper spindle positioning, likely regulating septin ring deposition at the bud neck.
What are the official names of this protein?
E3 ubiquitin-protein ligase DMA2, Checkpoint forkhead associated with RING domains-containing protein 1, Defective in mitotic arrest protein 2, RING-type E3 ubiquitin transferase DMA2.
What is the protein family that this protein belongs to?
Belongs to the DMA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRIP1_MOUSE
Sequence: MIAVSFKCRCQILRRLTKDESPYTKSASQTKPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEYDVSVMDSVATASGPLLVEVAKTPGASLGVALTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEILPHHQTRLALKGPDHVKIQRSDRQHPWDAWASNQCGVHTNHHHNTYHPDHCRVPALTFPKALPPNSPPAMVPSSSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRLKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPVTGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDAQSASSPKKFPIPGHSGDLGDGEEDPSPIQKPGKLSDAYPSTVPSVDSAVDSWDGSGIDASYGSQGSTFQTSGYNYNTYDWRSPKQRTSLSPVPKPRSQTYPDVGLSNEDWDRSTASGFVGASDSADAEQEENFWSQALEDLETCGQSGILRELEEKADRRVSLRNMTLLATIMSGSTMSLNHEAPMARSQLGRQASFQERSSSRPHYSQTTRSNTLPSDVGRKSVTLRKMKQEIKEIMSPTPVELHKVTLYKDSGMEDFGFSVADGLLEKGVYVKNIRPAGPGDVGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRNPLASQKSIEQPALPSDWSEQNSAFFQQPSHGGNLETREPTNTL
What is the function of this protein?
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (By similarity).  Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
What are the official names of this protein?
Glutamate receptor-interacting protein 1, GRIP-1.
What are the subcellular locations of this protein?
[Isoform 2]: Membrane; Lipid-anchor. SUBCELLULAR LOCATION: Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cytoplasm. Endomembrane system; Peripheral membrane protein. Postsynaptic cell membrane. Postsynaptic density. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities.
Protein: CLPB_RHOBA
Sequence: MAFRIDKLTTQAQNVVAEAQAQATSAGNAEIDPLHVLSAAVNQRDGITTPLLEKINVDVPKLKSLLTSELEKLPHASGMGQARVSAKLQAALEASATSAESLKDEYVSTEHLLVGLARTDNKAKNLLSLLGVSDNDLLTAMSQIRGSARVTDPNAESTYQALEKFGIDLTQLAQSGKLDPVIGRDNEIRRVIQVLSRRTKNNPVLIGQPGVGKTAIAEGLALRIFEGDVPQSLKGKKVVSLDMGALVAGAKFRGDFEERLKSVLREVKDSDGKVILFIDELHLVVGAGNAEGSADAANLLKPELARGALRCIGATTLDEYRQHIEKDAALERRFQPVFVGEPNVEDTVAILRGLKPRYESHHGVRITDSALVAAANLSDRYIADRFLPDKAIDLIDEAASRLAMEKESVPEPIDRLQRRLRQLELVHRQLVDEQEASAVDKRVEVEEEMESAKAELASLKEQWETEKMGLDDVQSVRQEVDQLQHRFAQLDADAKEKQLRGESPEDAYSEMLQVQSRLRELQARIDEAEKHDDSADQTKEEPGDEKRRLLRKEVTEEEIAEVVSTWTGVPVTRMMETERAKLLVMEERLHQRVVGQDEAVTAVSDAVRRSRSGLQDPNRPIGSFLFLGPTGVGKTELCKALAEVMFDDESAMVRIDMSEFMERHSVSRLIGAPPGYVGYEEGGKLTEAVRRRPYAVILLDEMEKAHPDVFNVLLQVLDDGRLTDGQGRTVNFTNTVVVMTSNVGSQVIQRVTEEGGGEDEMRQAVEDALKARFLPEFLNRIDDTVIFHPLQQTQIRRIVQLQLEELRSRLAANGLSFEITDAAIDQIAEVGYDPAYGARPLKRVIQREVQNPLASAILKNSYAEGTTIKIDHDGDQFVFSG
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_PSEA6
Sequence: MRLCDKDILTHLQEGKISITPEPDYAEISGVTVDIRLGNKFRVFTEHQAPYIDLSGPKAQVQEALNTVMSDEISVGQDKSFYLHPGELALAVTLESVTLPGNIVGWLDGRSSLARLGLMVHVTAHRIDPGWSGNIVLEFFNSGKLPLALKPGMKIGALSFEVMSDFAEKPYNARVDAKYKNQEGAIASRISGDDKTSTQ
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: LAT5_LACTA
Sequence: MKYCVVILALLVALVCITESRSTETGYAVAETLEDNDLDELQAYLEEIAEASEMEDFSNIEEARGFFGKMKEYFKKFGASFKRRFANLKKRLG
What is the function of this protein?
Has antimicrobial activity against.  Gram-positive bacteria (A. globiformis VKM Ac-1112 (MIC=1. 1 uM), and B. subtilis VKM B-501 (MIC=0. 6 uM)), Gram-negative bacteria (E. coli DH5-alpha (MIC=0. 6 uM), E. coli MH1 (MIC=0. 6 uM), and P. aeruginosa PAO1 (MIC=18 uM)), and yeasts (P. pastoris GS115 (MIC>37 uM), and S. cerevisiae Y190 (MIC>37 uM)).  Also has a moderate hemolytic activity against rabbit erythrocytes.  Causes paralysis, but is not lethal when injected into insect (M. domestica) larvae.
What are the official names of this protein?
M-zodatoxin-Lt5a, M-ZDTX-Lt5a, Latarcin-5, Ltc-5.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 03 (latarcin) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC2_MAIZE
Sequence: MAERANLVFHNKEIDGTAMKRLISRLIDHFGMGYTSHILDQIKTLGFHQATTTSISLGIEDLLTIPSKGWLVQDAEQQSFLLEKHYYYGAIHAVEKLRQSVEIWYATSEYLKQEMNSNFRITDPSNPVYLMSFSGARGNASQVHQLVGMRGLMADPQGQMIHLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTADAGYLTRRLVEVVQHIIVRRRDCGTIQGISVSPQNGMTEKLFVQTLIGRVLADDIYIGSRCIASRNQDIGIGLVNRFITAFRAQPFRAQPIYIRTPFTCRSTSWICQLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTADLIRSPSNGKIQFNEDLVHPTRTRHGQPAFLCYIDLHVTIQSQDILHSVNIPLKSLILVQNDQYVESEQVIAEIRAGTSTLHFKEKVQKHIYSESDGEMHWSTDVYHAPEYQYGNLRRLPKTSHLWILSVSMCRSSIASFSLHKDQDQMNTYSFSVDGRYIFDFSMANDQVSHRLLDTFGKKDREILDYLTPDRIVFNGHWNCFYPSILQDNSDLLAKKRRNRLVVPLQYHQEQEKERISCLGISMEIPFMGVLRRNTIFAYFDDPRYRKDKRGSGIVKFRYRTLEEEYRTQEEEYRTREEEYRTREEDSEDEYESPENKYRTREGEGEYKILEDEYRTLEDEYETLEDEYGILEDEYRTLEKDSEEEYGSLENKYRTREGEGEYEILEEESEEEYGSSEDGSEKEYGTLEEDSEEDSEEDSEDEYGSPEEDSILKKEGFIEHRGTKEFSLKYQKEVDRFFFILQELHILPRSSSLKVLDNSIIGVDTQLTKNTRSRLGGLVRVKRKKSHTELKIFSGDIHFPEEADKILGGSLIPPEREKKDSKESKKRKNWVYVQRKKFLKSKEKYFVSVRPAVAYEMDEGINLATLFPQDLLQEEDNLQLRLVNFISHENSKLTQRIYHTNSQFVRTCLVVNWEQEEKEGARASLVEVKTNDLIRDFLRIELVKSTILYTRRRYDRTSVGLIPNNRLDRNNTNSFYSKAKIQSLSQHQEVIGTLLNRNKEYPSLMILLASNCSRIGLFKNSKYPNAVKESNPRIPIRDIFGLLGVIVPSISNFSSSYYLLTHNQILLKKYLFLDNLKQTLQVLQGLKYSLIDENKRISNFDSNIMLEPFHLNWHFLHHDSWEETLAIIHLGQFICENLCLFKLHIKKSGQIFIVNMDSFVLRAAKPYLATIGATVHGHYGKILYKGDRLVTFIYEKSRSSDITQGLPKVEQIFEARSIDSLSPNLERRIEDWNERIPRILGVPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHIEIIIRQVTSKVRVSEDGMSNVFLPGELIGLLRAERAGRALDESIYYRAILLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGIIPVGTGFQKFVHRSPQDKNLYLEIQKKNLFASEMRDILFLHTELVSSDSDVTNNFYETSETPFTPIYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TTI1_YEAST
Sequence: MNSDTNAFKDIRISCVELSRIAFLPTESFDPNSLTLLACLKKVEEKLSAYEDDSLSPKFADYVFVPIASLLKQPALGESQTEYVLLIIFHLLRTCWSSNGKFSEQLGQQLFPLITFLVSSDKDNQKLITRSDEFKYAGCLVLHQFFKSVRSQRYHKEFFSNSKPNLLPALGHSVTILLKILEQSPQNNELQFKALASLEVLFQDIISDGEMLSFILPGNVSVFAKILTKPGRQIHYKVCVRTLEVLAKLLVLVYDDFSLDIKVNKLTDIRELSDTKLKHEINQSFMFNGPIVLLRTDGKTHRDTSWLTATSGQINIALEAFIPKLLKRNNESIDEALATFVSILLTRCENSLNNCEKVLVSTLVHLERDPMSKLPSHLVKLKEVVNEDLHKLSDIIRFENADRLSSLSFAITILEKNNERDTMINEVVRCLFESLNESIEPPSLINHKERIIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKFTYHMGSLLLERHILNDVVTELISEQVDSPRTQKIVALWLSTNFIKAMEKQPKEEEVYLQFESDANYSSSMVEEVCLIVLEFCNELSQDISMEIEGKGIKKSDEFAVCTVLFSIETICAVMREEFQPELIDYIYTVVDALASPSEAIRYVSQSCALRIADTLYHGSIPNMILSNVDYLVESISSRLNSGMTERVSQILMVICQLAGYETIENFKDVIETIFKLLDYYHGYSDLCLQFFQLFKIIILEMKKKYINDDEMILKIANQHISQSTFSPWGMTDFQQVLNILDKETQVKDDITDENDVDFLKDDNEPSNFQEYFDSKLREPDSDDDEEEREEEVEGSSKEYTDQWTSPIPSDSYKILLQILGYGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVASTWDSIIQCVLCSDYSIVQPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHNHEKKSISKHVKFPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVPVEKISSMSLIVGDIVWKIRNIN
What is the function of this protein?
Component of the ASTRA complex involved in chromatin remodeling.
What are the official names of this protein?
TEL2-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the tti1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1915_VIBC3
Sequence: MNIDVVLLLEQNPILLIFVVLAIGLSFGKIRFGSFQLGNSIGVLITSLIMGHLGFSFTPEALTIGFMLFIYCVGIEAGPNFFGIFFRDGKHYLILSLVVLITATWIAYFGGYYLNLDYGLAAGMMAGALTSTPVLVGAQDALNSGLAAVPRHMDLSLILDNVSVGYAMAYLIGLISMIMFAKLLPKLQKQNLSDSAQQIAQERGLGSQRKVYLPIIRAYRVGPELINWIDGRNLRELGIYRQTGCYIERIRRHGILAHPDGDAILQEGDEIALVGFPDSHARLDPSFRNGKEVFDRNLLDLRISEEEIVVKSDSIAGKRLSDLNLSEYGCFLNRVVRAQIEMPMDLDIVLAKGDVLQVSGEKSKVKGLADKIGFISVHSQMADLLAFCSFFILGILFGLVTMTFGQVSFSLGNAVGLLLSGITLGFLRANHPTFGYVPQGALNMVKDLGLAIFMVGIGLNAGSKMFQHLSEVGVQVIGLAFLVSVVPVVFAYLVGAYILKMNRALLFGAIIGARTCAPAMDVVNEYAKSTIPALGYAGTYAIANILMTLTGTIFILLS
What are the official names of this protein?
Putative transport protein VC0395_A0715/VC395_1212.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_BURM1
Sequence: MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPVMPGVLILEALAQAAALLTFSEEQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAP1A_THEAO
Sequence: DDCLGMFSSCDPNNDKCCPNRKCSRKDQWCKYQLW
What is the function of this protein?
Gating-modifier toxin that inhibits both sodium (Nav) and calcium (Cav3) channels by inducing hyperpolarizing shift in voltage-dependence of activation and steady state inactivation.  Inhibits Nav1. 1/SCN1A, Nav1. 2/SCN2A, Nav1. 3/SCN3A, Nav1. 6/SCN6A, Nav1. 7/SCN9A and Cav3. 1/CACNA1G sodium and calcium channels at nanomolar concentrations (IC(50)=81-301 nM).  Surprisingly, selectively slows fast inactivation of Nav1. 3/SCN3A.  Also shows moderate inhibition of Cav3. 2/CACNA1H calcium channels (IC(50)=1233 nM).  Ex vivo, nearly ablates neuronal mechanosensitivity in afferent fibers innervating the colon and the bladder.  In vivo, in a mouse model of irritable bowel syndrome, intracolonic administration of the toxin reverses colonic mechanical hypersensitivity.
What are the official names of this protein?
Mu/omega-theraphotoxin-Tap1a, Mu/omega-TRTX-Tap1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 59 (Tltx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSX_SULNB
Sequence: MIRIAIDAMGGDFGPEPIIEGVVQALEEKTFQPILVGDKEEILSLLPQYYIDKVEIVEATDVIDMSDQATNALKRKDSSIYKAVELVRNKEADAVLSAGHSGATMTLATLRMGRLPHISKPALATLMPSLGKNKTLVLDVGAVTDCTPQNLYEFGAMGEAYVEKILNIRNPRVGLLSNGSEDSKGNALTKEAFVLLKNLRGFVGNVEGKDIFNGKVDVVVCDGFTGNIMLKASEGVVTTVFELMKQYIRKSLPAKIGALMMRKKVFANMKRQVDKDEYGGAPLLGVDGCAIVSHGASNAKAIKNAIFQAILFTESGVNSQIEELLSEKE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CHM4B_XENTR
Sequence: MSLIGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLPNVPAAVLPAKPVKKKQEEDDDDMRELENWATA
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein. Midbody.
Protein: Y1118_BACCN
Sequence: MAKIGVESSLTDVQQALQQKGHEVISLQSESDAKECDCCVITGQDSNVMGISDVSTKGSVIKASGLTTDEICQQVESRV
What are the official names of this protein?
UPF0180 protein Bcer98_1118.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.