PharMolix/UniProtQA huggingface dataset:
Protein: CIPK4_ARATH
Sequence: MESPYPKSPEKITGTVLLGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKPARSIIYKLLDPNPETRMSIEAVMGTVWFQKSLEISEFQSSVFELDRFLEKEAKSSNAITAFDLISLSSGLDLSGLFERRKRKEKRFTARVSAERVVEKAGMIGEKLGFRVEKKEETKVVGLGKGRTAVVVEVVEFAEGLVVADVKVVVEGEEEEEEVESHWSELIVELEEIVLSWHN
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 4, SNF1-related kinase 3.3, SOS2-like protein kinase PKS9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: PSAJ_GUIAB
Sequence: MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PORTL_HHV6U
Sequence: MHRASANSLLNSVSGSMMWRNQSSGRRPSKRLSDNEATLSTINSILGAEDMLSKNLLSYLPPNNEEIDMIYPSEQIMTFIEMLHGHKNFFKGQTIHNALRDSAVLKKQIAYGVAQALLNSVSIQQIHDEWKRHVRSFPFHNKKLSFQDYFSVWAHAIKQVILGDISNIINFILQSIDNSHYNRYVDWICTVGIVPFMRTTHTAPNLYNLLQQVSSKLIHDIVRHKQNIVTPVLLGLSSVIIPDFHNIKIFRDRNSEQISCFKNKKAIAFFTYSTPYVIRNRLMLTTPLAHLSPELKKHNSLRRHQKMCQLLNTFPIKVLTTAKTDVTNKKIMDMIEKEEKSSDAKKSLIKFLLNLSDSKSKIGIRDSVEGFIQEITPSIIDQNKLMLNRGQFRKRSAIDTGERDVRDLFKKQIIKCMEEQIQTQMDEIETLKTTNQMFERKIKDLHSLLETNNDCDRYNPNLDHDLENLSLSRALNIVQRLPFTSVSIDDTRSVANSFFSQYIPDTQYADKRIDQLWEMEYMRTFRLRKNVNNQGQEESITYSNYSIELLIVPFLRRFLNIYNLESIPEEFLFLSLGEILLAIYESSKIKHYLRLVYVRELNQISEVFNLTQTHPENSEPIFDSNIFSPNPENEILEKIKRIRNLRRIQHLTRPNYPKGDQD
What is the function of this protein?
Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging.  Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid.  Binds to the molecular motor that translocates the viral DNA, termed terminase.
What are the official names of this protein?
Portal protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae portal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DNLJ_SORC5
Sequence: MTQAHHDDAGARNALQGGLATDPKHKARIEELAERIEKYRASYYAGHPEISDAAFDALEDELRALDPAHPVLARVGSASLITEWEKARHEIPMGSLNKVVSEDELLGWVARCDEILVKDGHGDGGTGAAPPAPGSISSVAGDLFVAEKLDGISIEVIYKGGKLVDAITRGDGEWGERITANVARMKGIPSRIREKGRLSVRGEIILRLSDMKRHFPGVTSPRNMAAGAAKRFDGQGAEHCTVLFYDVADHLEIPTCRARFAWLRELGFATPQTAHGSVEDVVKLYRRYSSELRAGLDYEIDGLVVYVDSLHVQGLLGDVNRRPRGAVAFKFASPAKVTTVVAIQWDTGPSGRVTPVAIVEPVELAGANVRRASLHNSANVRSLGIGVGDEVLVSRRNDVIPYVEEVVEKRGPVAVPPSVCPVCSAPLVVEGEYLLCRNAACRALIEGRIHNWIDAIGALEWGDKLIEQVVAAGLVREPLDLYKLTVKSIADLDRRGEKSATKCLEQLKSRLPLALPVFLAALGIEGFAIQTARLLVSAGYTTIEKLLAAGEDELAGIPGLGAIKAASIVRGLRARSDEIGRLLAAGIVPVAPEAEGPLAGLTFCFTGAGARPRGELTHLVESSGGRVLNSVTKELNYLVIADVASTSSKAVKARKYGTKLITEDDLDKLIAERRGG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PEPQ_SHEB2
Sequence: MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQLIFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLPTDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTKTEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLSFLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHAKVAQMLLDFDLATGDVQGLVDQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQQINWQTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLTD
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: YF81_THET2
Sequence: MGVMEILVSTLEAVPGYRVAQVLGVVKGSTVRSKHLGKDLLAGLRTLVGGELPEYTEMLQEAREVAEARMLEEARRLGAHAVLGVRYATASVMQGAAEILVYGTAVRLEPARER
What are the official names of this protein?
UPF0145 protein TT_C1581.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PYRH_VIBVU
Sequence: MTTNPKPAYQRILLKLSGEALQGSEGFGIDPTVLDRMAQEVKELVELGVQVGVVIGGGNLFRGAGLAQAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARVMSAIPLNGVCDDYNWADAIRELRQGRVVIFAAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPVANPDAELYDKLSYTDVLEKELKVMDLAAFTLARDHKMPIRVFNMNKPGALRRVVMGEAEGTLITA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLR_SALCH
Sequence: MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPASRLTEDRFISQGELVRDTAKDISTALGLKPPVA
What is the function of this protein?
Negative regulator of allantoin and glyoxylate utilization operons.  Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
What are the official names of this protein?
HTH-type transcriptional repressor AllR, Negative regulator of allantoin and glyoxylate utilization operons.
Protein: RL24_FRAP2
Sequence: MNRLKKGDDVIVIAGKDKGRRGVVKSFAKGGSLVLVEGINIVKKHVKPNPNRGVEGGVVEKELPVDASNVAIFNPATEKADRVGYKFVDEKKVRYFKSNGELVDL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CRGS2_CHIID
Sequence: MGKIIFYEDRNFQGRNYECSSDCADLSPYFSRCNSIRVESDWWVLYEKPNYMGYQHVLTRGEYPDYQRWMGFNDCVRSCRVPTHTQRPYRMRIYERPDFGGQMMEFMDVCPSVYDRFRYRDIHSSHVMGAYWIFYEHPNYRGRLYFMRPGEYRRYSDWGGYSSTIGSFRRIME
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin S-2, Beta-crystallin S-2.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: THIC_THESQ
Sequence: MTQMEMARKGVVSDEMKKVAEYEGVDVEIVRQKLAEGRAVLPKNKLHRIERPMIVGEGFSVKVNANIGTSQGFSSLEEEKEKARVAIEYGADSLMVLSTWGDLREIRRAIVEMSPVPVGSVPIYDSAVRSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLDRIKSSRRVLKIVSRGGAIIAGWMIKNNRENPFYEHFDELLDIAKDYDITLSLGDGMRPGAVVDASDAQQFEELFVMGELVEKAREKGVQVMLEGPGHVPLNEVEMNVRLMKKIGKGAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAIVADVARGNKKAWELEKKMALARKNFDWETMFSLSLGKDVAKKKYEERPYPDKGCSMCGPFCAIKIAEEFS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y901_STRZT
Sequence: MSNIYDSANELSRGLRGLPEYKTVKAAKDAIAADAEASKIFTEYLAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKIVFEPVSELLK
What are the official names of this protein?
UPF0342 protein SPT_0901.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: TOLB_PSEPF
Sequence: MRNLLRGMLVVICCMAGIVMADEKNILVTSGSDRATPIAVVPFGFQGGAVLPDDMAEIIGNDLRNSGYYSPIPKQNMISQPSQPSEIIFRDWKAVGAQYMMVGSIVPAGGRLQVQWALFNVATEQKVADGSVSGTTEQLRDMAHYISDQSFEKLTGIKGAFSTRLLYVTAERFSEKNTRYTLQRSDYDGARAVTLLQSREPILSPRFAPDGKRIAYVSFEQKRPRIFMQNIDTGRREQITNFEGLNGAPAWSPDGNRLAFVLSKDGNPDIYVMNLGSRQITRVTAGPGINTEPYWGKDGSTIYFTSDRGGKPQIYKTSAGGGGAERVTFVGNYNANPKLSADEKTLVMIHRQDGFTNFKVAAQDLQRGSVKILTDSTLDESPTVAPNGTMVIYATRQQGRGVLMLVSINGRVRLPLPTAQGEVREPSWSPYLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NU4LM_VARVV
Sequence: MPSIFINIILAFIIALLGMLIFRSHLMSSLLCLESMMLSMFILSTLTILSLHLTMSFMMPILLLVFAACEAAVGLALLVTVSNTYGLDYIQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PRGR_PAPAN
Sequence: MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFQGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPLDEKTQDQQSLSDVEGAYSRAEATRGTGGSSSRPPEKDSGLLHSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQGVLSPLMSRSGCKAGDSSGTAAAHKVLPRGLSPSRQLLLPASGSPHWSGAPVKPSPQPAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTTMDFTHVPILPLSHALLAARTRQLLEEESYDGGAGAASAFAPPRSSPSASSTPVAVGDFPDCAYPPDADPKDDAYPLYGDFQPPALKIKEEEEGAEVSARSPRSYLVAGANPAAFPDFPLGPPPPLPPRAPPSRPGEAAVTAAPAGASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGAGGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLQQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNESQALSQRFTFPPGQDIQLIPPLINLLVSIEPDVIYAGHDNSKPDTSSSLLTSLNQLGERQLLSVVKWSKLLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: ARP3B_XENLA
Sequence: MAARLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRLMKGVDDLDFHIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFTQQLLRDREVGIPPEQSLETAKAVKERFSYVCPDLVKEFSKYDTDGAKWIKQYTGVNAVSKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDVKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity).  Seems to contact the pointed end of the daughter actin filament (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 3-B.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: TPPC5_BOVIN
Sequence: MEARFTRGKSALLERALARPRTEVSLSAFALLFSELVQHCQSRVFTVAELQARLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: RS10_PROM1
Sequence: MSTAIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: UREE_HAHCH
Sequence: MIRITERYIETEQTPVIAGVISLTYDERKRGRLRAKTQSGEDVGLFLERGKTLLDGDLLMAENGDIYTISAAPETVATAQANDPRQFAQICYHLGNRHTPLQIGELWVRFQPDHVLEDLCRLYGLDVVRESAPFNPENGAYGGHSGHSGHSGHSGHHHGHDHSHEQSRQDAKELSARYHFHAPDHEHPHGHVHLHAHPHEH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_PSEP1
Sequence: MAEAEKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDEANQCKIGDKVSIRETRPLAKTKSWALVEVLERAVEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ASTC_ECOHS
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTLNHRYGLFSEIRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: COX2_TACSP
Sequence: MAYPLQYGLQDATSPIMEELLHFHDHTLMIVFLISFLVLYVIFAMLSTKLTHTSTMDAQEVETIWTILPAVILVLIALPSLRILYMMDEIYNPALTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTTELKPGELRLLEVDNRVVLPMELPIRMLVSSEDVLHSWAVPSLGLKTDTIPGRLNQATLSSTRPGLFYGQCSEICGSNHSFMPIVLEMVPLKQFESWSATMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: WNT5B_AMBME
Sequence: MPGIRLLLAAALLCCPPPAGATSWWSLAQNPVQRPEMYIIGAQPVCSQLSSLSPGQKKLCQLYQDHMMYIGEGAKTGIKECQYQFKQRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRTTRPKDLHRDWLWGGCGDNVDYGYRFAKEFVDAREREKNYPKGSEEQARTLMNLQNNEAGRRAVYKLADAACKCHGVSGSCSLKTCWLQLADFRKVGDHLKEKYDSAAAMRINRKGKLELVNNRFNLPTVEDLVYTDQSPDYCLRNESTGSLGTLGRLCNKTSEGMDGCELMCCGRGYDQFKTVQVERCHCKFHWCCFVKCKKCTEIVDQYVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PLPR1_DANRE
Sequence: MASDNTHRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFGIHIQGFFCNDADLLKPYPGPEESSFIQPLILYCVVAAAPTAIIFVGEISMYIMKSTGEALLAQEKTIVTGECCYLNPLIRRIIRFIGVFAFGLFATDIFVNAGQVVTGNLAPYFLNVCKPNYTGLDCHFSHQFIANGNICTGNQVVVERARRSFPSKDASLSVYSAVYVTMYITSTIKTKSSRLAKPVLCLGLLCAAFLTGLNRVSEYRNHCSDVVAGFILGSSIALFLGICVVNNFKGTHSTPTKQKQEDYRGLPLMTFPRVESPLETLSAQGKSCQATLLTSSQPNTWSA
What is the function of this protein?
May play a role in neurite outgrowth and neurogenesis.
What are the official names of this protein?
Phospholipid phosphatase-related protein type 1, Inactive 2-lysophosphatidate phosphatase PLPPR1, Lipid phosphate phosphatase-related protein type 1.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection.
Protein: ACT_PUCGR
Sequence: MEEEVAALVLDNGSGMCKAGFAGDDAPRAVFPSICGGPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKVNREKMTQIMFETFNAPAFYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLIKILMERGYSFTTTAEREIRRDIKEKLCYVGLDFEQEMQTASQSSALEKSYELPDGQVITIGNERFRCPEALFQPSLLGLEASGIHETTYNSIMKCDLDIRKDLYGNVVMSGGTTMYSGISDRMQKEITALAPSSMKVKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LSPA_LACPL
Sequence: MWIYLILMVALVIIDQVIKAAIVSHIALGASTSIVTGLLSLTNLHNNGAAWSILEGKMWFFYLISVIALIVMGYLLWRLRGKWLYEVGISLMIAGTLGNFIDRLRIGYVVDMFQLDFINFPIFNFADSCLTVGVIFILIGVLRDDSFEK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YL676_MIMIV
Sequence: MTTFDLDDFLKSYKPKKVDLSSYTNHTKLKGYTYITKDDFNNLIPNRTYIKYILRSDVGTENNISKQIHCGGFFLSGGNFSGKKFVQSDDWITWTHLFLKYCPHPESNLNGEFTEHKFYLKTTKYYLFYRYYDKKSDIYNLKSIKLKKIKKLKKNSDSKSMKKTH
What are the official names of this protein?
Uncharacterized protein L676.
Protein: Y2948_STRCO
Sequence: MSGMTEVSSLTGRLLVATPALADPNFERAVVLLLDHDEEGSLGVVLNRPTPVDVGDILEDWADLAGEPGVVFQGGPVSLDSALGVAVVPGGASGERAPLGWRRVHGAIGLVDLEAPPELLAPAVGALRIFAGYAGWGPGQLEDELTEGAWYVVESEPGDVSSPFPERLWREVLRRQRGDLAMVATYPDDPSLN
What are the official names of this protein?
UPF0301 protein SCO2948.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: APD3_PIMDI
Sequence: GKPSRPRPAPIQPRPPHPRL
What is the function of this protein?
Not active against S. typhi.
What are the official names of this protein?
Apidaecin 3+.
What is the protein family that this protein belongs to?
Belongs to the apidaecin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOBB_METJA
Sequence: MRVIGVIGYKDSGKTTLIEEILKHSDKKIAVIKHTKEDVEVDKKGTDTYRLSNAGAKITVLATDSKTVFFTDRMDLENILSVLSDYNIDFVIIEGFKEALKRLNIPKIVMLKDKDGSDLIDDHTAMIIEDYNYNIDDVLKVIYEKAVVPTMNLNCGHCGYNCRTFVKAVVKGEARWDDCVLAKGIKIIVDGKIIPAVPFVSKIVGSTIKAMIETLKGVDNPKTIKVEIDVSKLK
What is the function of this protein?
GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor.  May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD.  Displays a weak intrinsic GTPase activity (By similarity).
What are the official names of this protein?
Putative molybdopterin-guanine dinucleotide biosynthesis adapter protein, MGD biosynthesis adapter protein, Molybdenum cofactor biosynthesis adapter protein, Moco biosynthesis adapter protein.
What is the protein family that this protein belongs to?
Belongs to the MobB family.
Protein: PLP_RICCN
Sequence: MKKLSVIFLSVSMLSGIAFADKDKVVATYKGGEVKESQIMKEFKPQLNLQSGETIKNFDDFPPQDQEKLIKIYVNNLLLKEEVAKSNITSSKEFQEKLENAKNQLAQQELLANYIKSNITDKMFDDEYNKYVGNLKGKEQIKVAHILVKSQKEANDIKTKLSKGGNFTKLAEELSLDKASASNGGVIGYILLNQPGQLVPEFEKKAFALKVNEVSTPVKTDFGWHIIKVLEKKPVPIPTKEEAKVTIDNILAAEVLKKYIADLEAKANLKIMLPKADSKAGS
What are the official names of this protein?
Parvulin-like PPIase, Peptidyl-prolyl cis-trans isomerase plp, Rotamase plp.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
What are the subcellular locations of this protein?
Cell outer membrane.