PharMolix/UniProtQA huggingface dataset:
Protein: VERP_CLORO
Sequence: MTLPTSLCDLFAQAASRCPDNLAVDHTEGSLTYRQLDDVSNSLANMLMGLGVNQLSPVILLTSHGTFNIIATLAILKVGSCCVPIDRATWPQERINYVCQTVANSVILNTTSEPFMPSEGAGDVLNYTSMQSGPSFRPNPVFQAHKVAADDTAYIIFTSGSTGKPKGVLISHKSLCLYSTTSPINLDIGPGDRLLHILSVAFDACACMLFSALGNCGTIVPAQAEDVLLQAPSCTVLAATPAMLKNLPSPTTENSIFSNLSRVILGGETASPDLLGLWIDAGVQVLIAYGVTETTSMGSIYRVERDPRTDAINPYIIGGVLEQSPIWIVDSELRIIKNENSEGEIIVGGDGVAQGYYNDEQKTRSNFIHWNGSRIYRTGDFGCWVLDANGRRVIEFRGRKDRTVKNQGYLVNLDRDVEAALYRVGESFGLTSVRAVATGNGIVAVVTPSNVNTSALIEKAKDIMCSYCIPYRIGAVDDLPLSPNGKVQHNELAELIKIIDEGQHNQENKADSQLSEKIERGKFGDDRHLDTLLTVARDVLSLPGQSFRILQPHDSFFAVGGSSLLAFKLVSVLGQHGLNIPARELFKNQPFSDVAPLITSRAHSSTWRLTEHDDKTQQTLAELQNQACQMLGLVQNSFEIGPLTSLQLDLALPTLGDESRNINQVKIAYNAPHSGIMRRAWQGLWQSEPVFRTEVSLAVGCGALIVHNKPFRKYRVVSHSCRDKYEEAVKGINMGVGLGCTLDVLTYHKTSDGLPYLPVSSNHNSSSSETDELTVVLTIHHSLMDGESLKLLLDKVDRIALGFSQPLSGSSINANLALIKTQNSRDSEVRSFFSDYLRHLSPENIAPGQVSATENLEGSSSRETAFFETSVSSVEVSDFAKLNCSSAACIYYIAWAMAVAAFDNSPDVLIGAVVSNRPALQHHEHAIGAYMSTLPLVFNFRDDEETVVDRIQKTMEDLATVGEYAWARSDQCGIGRRMRTLLSMQFPLPNESSKPPALWTESAENSDFPLCLLVESSGDFRMLYDATQFNWEAAQRLGQHFKHALYSLHHETRVTDCMTVNRLQENLAKQSEIFRLKPSERIVKQVLEQVMGQFPSLIAVEDCLGGKLTYSELDKLTNVIAHHINSTVPNAEVIALYSDGTIQWILGLLGTVKAGCTYVNLDPRSSVSRRETICKQCGAEALLLPNASQASEAPLMDNLKVLAVDEMLSGNSKKHNGKQPDRASLDSSLVIVFTSGTTGNPKGILISNRSFLSMETSYGTTMFAAPGRRIAQFMSPVFDVCNMEIFSALLHGATLVLRDPSDPYANLHRVNTAAVTPSAMAVIDLDDFPNLQLIYACGEPVTKSLVKRYTKRALLYNAYGPAECSILTSIERLIPGDQVTVGRPLSTVRVYILDEDQHPMAPGDRGEVCVAGVQVLRDYINAPEQAARNILTDPWYPGERMYRSGDSGSIGRDGRLSLHGRIDRLVKLRGFRVELAGVEHAVVSGPTEEGVSQCAAIAVNGLLIVYVSFERSQQHDSLSNKERIAQLLSRLREQLLPSSVPQEIVHIDNFPRTINGKIDTRALETQYSSYKNTSIEKAVGDCPITRPKIEDKLAHEWRQVLQLIPETQLQESDDFFKLGGHSVSIMLLATRLTAAFGKKITVRELLPSPTFKDQINMVRALLEIETFHKEEPQMLPPLLTEELTSIEKQVWFQHQVATTVTAFNIIRVIQIEGAVEIDKLCQSLNNILSIDPIFRSNIVEGPKGPARILRNSAPTVQEVDEFDIERALHHRFNLAHDYLIQVYLARHGCKGDNNDHATLVILTSHVIADLGTLQNFLQLTSTAYSGSTLVPLDRPKHLDSKSWTRIPTFSERKFWSEYLKGLIRRLGLTHHQLALAVGALFLQWFSAEDDLVLGAPNSGRPTSQEQESLGQFLDRLPIRITPNDLGNDDTMTKLTEILNRVRHSSLKALSNAISFSNIIQDLGYPSGGLEHPLFECDCFYTVS
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of 11'-deoxyverticillin A, one of the dimeric epipolythiodioxopiperazines (ETPs) from the verticillin family that act as mycotoxins (PubMed:28376389).  11'-deoxyverticillin A is required for normal conidiation (PubMed:28376389).  The nonribosomal peptide synthetase verP is speculated to be responsible for condensation of amino acids to form the carbon skeleton of verticillin, whereas the cluster-specific tailoring enzymes are involved in further modifications leading to the production of 11'-deoxyverticillin A (Probable).
What are the official names of this protein?
Nonribosomal peptide synthetase verP, NRPS verP, Verticillin biosynthesis cluster protein P.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: DEOD_LISW6
Sequence: MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSYDVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGVEKGLSLKVGNVFSADRFYNDQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TVP38_CANGA
Sequence: MPTDNADLGQEDIDVFDNGRESFDRLNKPVLDGIGIEGNDDDDDDYLTLYNMTPRERLMYTFRRSMYKALDHFNSLPKWQRLLIILFGALVIVLGILMLIFHNKILDKVLETSKDLNERSSTNFILLVLLFFVGFPPMIGYSFLSTSTGLIYGVSFHGWFVLALGSVTGSVASFYVFKNLLHSRAEKLVHMNKRFEAFASILQEDNSYLMLALLRLCPFPYSLTNGAIAGIYGISVKNFTIANIITTPKLLIYLFIGARIKNMAEDHSTSSRIFDLVSILITLIIFTLTAWLLYFKTKQRYAQLKNQAVAQNSSANREVDFEI
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein TVP38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PSMD3_DROME
Sequence: MTNATDIGANDVEMEVDPTAETLADEKKNQDVAAVQEIREQIRQIEKGVASKESRFILRVLRNLPNTRRKLNGVVFRNLAQSIYPAGADREAAVALMPAVEKDATELPDVPKKQVATKAPIAEVDAYFYLLLLVKLIDASDLKRAGISADALMAKISIQNRRTLDLIGAKSYFYFSRVAELKNSLEGIRSFLHARLRTATLRNDFEGQAVLINCLLRNYLHYALYDQADKLVKKSVYPESASNNEWARFLYYLGRIKAAKLEYSDAHKHLVQALRKSPQHAAIGFRQTVQKLIIVVELLLGNIPERVVFRQAGLRQSLGAYFQLTQAVRLGNLKRFGDVVSQYGPKFQLDHTFTLIIRLRHNVIKTAIRSIGLSYSRISPQDIAKRLMLDSAEDAEFIVSKAIRDGVIEATLDPAQNFMRSKESTDIYSTREPQLAFHERISFCLNLHNQSVKAMRYPPKSYGKDLESAEERREREQQDLELAKEMAEDDEDGF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
Probable 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome subunit S3, Diphenol oxidase A2 component, DOX-A2, Regulatory particle non-ATPase 3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
Protein: LPXD_HAES1
Sequence: MQGYSLLELAQQIGATIRGNADVIVTDIAPLDKADNNQLTFISNPKFREHLLQSQAGALIVTESDIEFCSAQSNLLVVKDPYVAYAILAQYMDSTPKAAQGIHQSAVVSDTATLGQHVSIGANAVIEDGVILGDNVVIGAGCFIGKHVQIGENTQLWANVNIYHDVKIGSDCLIQSGAVIGSDGFGYANDRGRWIKIPQTGTVIIGNHVEIGACTCIDRGALDATVIEDNVIIDNLCQIAHNVHIGTGTAVAGGVIMAGSLKVGRYCLIGGASVINGHMEICDKVTITGMGMVMRPITEPGIYSSGIPLQPNKVWRKTAALTLDIDKINKRLKAVEKKLAE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DNLJ_LEPBA
Sequence: MAKKTKAEDPKKRIITLRKEIGRHNDLYYKENAPVITDKEFDILVKELQKLESENPDLADVSSPTAQVGSDLSPQFSKFKHKVPVLSLENTYNETELSEWLEKTGIEENYSLEWKIDGASILLYYEKGKLTNCVTRGSGGIGDVVTENVKTISTIPHTLSEEMNLTVRGEIFMTFADFEEFNEEYGGKFANPRNLAAGSIKQKDPLDVAKRPLRIYVYDVYFSSSRKGINTHKDILSLLKKEKFPLAPDTTILTGKKLLREIESFRKKKDKMPFPVDGLVIKLDSLNLRESLGETSHSPRWARAFKFDALLKESTIEEIDFAIGRTGKVTPRAKVTPISLAGTTVTYATLHNQDYINQLGAGIGAKVLISKRGEIIPAVEKVTFPPKTIFVLPNQCPSCNTKLTKVDDSVDFFCTNRHCPERKLNQLIFFCSKKQMNIEGLGERQIQIFFEKGWVKDIPDLYTLEKYKPTLLELDGFGEKSVKIIFDAIEKSKEKDFRFTLPSIGLNEVGPKVTEILIENGYDSWDKLLTLSKSKTANEDLKAIHGIGPRTIEALLTHLKDKETLKLVATLKKLGLKFQADETEKSDLQPFVGQSWCVTGSFENFQPRDLAMDLITKHGGKKVTSVSSKTTHLLYGPGAGSKLDKATELGVKLVTESEFLDLLKQEGIAID
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ANEG_ASPA1
Sequence: MNATAQALVLPFITQVTRAVSLSENVKVLGGIPFAEDGTYLEWLSILGFTIGCYYVIYTFYALCFHPLRKYPGPWHLAVSNIPNRWSTISGNSSYWLYDLHEKYGPIVRVAPNEISYSDPQAWQDIYGPQPNQRLGMPKDPKFFSSFEDKKTAASIITSQPKDYMRMRHIYSYGFSKQVMLAKEEMIQGIIDRAMEALRQTKQQPQDIVQIFRATDFSIVTEIVFGKAYHIFDRPTYQPWFKSLMGWIRSTAVITATTDYPLGKLAAWLLTPRSVLKQRNVYLKYVNGEIEERIGESNAGRKDVVQLMFETTDQPKLAESDIRANLPFMVIAASETTTTLMSGMIAHLLNSPDALSQLTAEVRGRFRSPSDITIATVNNLPFLNACVNEALRVYPAAPTQLPRVVPGEGATVCNRWVPGGTKVYVAPYATFRSAENFYQPDAFLPQRWLPENGESFDVDKKNAWRPFGLGAHECPGQVITNLITRLIMCKLLLSFDLELCADSQDWLSRQPVWIVWDKPELLIKARPAAA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aculenes, a unique type of norsesquiterpenes that contain a nordaucane skeleton linked to an L-proline moiety and are of mixed biosynthetic origin (PubMed:31618514).  The pathway begins with the synthesis of dauca-4,7-diene by the terpene cyclase aneC using farnesyl pyrophosphate (FPP) as substrate (PubMed:31618514).  The cytochrome P450 monooxygenase aneF then performs the initial oxidation at C-12 of dauca-4,7-diene to yield asperaculane D (PubMed:31618514).  Asperaculane D is substrate of the cytochrome P450 monooxygenase aneD for C-10 hydroxylation to yield asperaculane E (PubMed:31618514).  The cytochrome P450 monooxygenase aneG then converts asperaculane E into aculene D via C-2 oxidation (PubMed:31618514).  The monomodular nonribosomal peptide synthtase aneB adenylates L-proline and the thiohydrolase aneE transfers this activated L-proline derivative to aculenes D and C to produce respectively aculenes B and A (PubMed:31618514).  The dioxygenase aneA converts aculene D into aculene C, and aculene B into aculene A by introducing the 5,6-alkene moiety (PubMed:31618514).  Asperculanes A, B, C and F, as well as 14-prolyl asperculane C, might be shunt products of the pathway (PubMed:31618514).
What are the official names of this protein?
Cytochrome P450 monooxygenase aneG, Aculenes biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIS4_LEPBA
Sequence: MLVLPAIDLLDNEAVRLLQGDYSKKTVYSSSPEKMIQVFEEQGATLIHIVDLNAAKTGKSENEKTIKKIKEKCTVDLELGGGIRTIDNMKFYDGLGVSRLILGTVAVEEPNVVEKAVSLFGQDRIVIGVDAKNGYVRTKGWESNSGILYKDFLTTMYGMGIRHVIFTDIARDGMMEGPNTLAYAELLETFPDLQLVASGGVSSKEDLVELYDKTNGKLFGAITGKAIYEGKLDLKESIRILNQKREK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_YERPN
Sequence: MPFTLGQRWISDTESELGLGTVVAIDVRMITLLFPATGENRLYARNDSPITRVMFNPSDTITHHEGWQLKVEEVTQENGLITYIGTRLDTEETGVAMREVLLDSKLTFSKPQDRLFAGQIDRMDRFALRFRARKYQSEQFRLPWSGLRGIRASLIPHQLHIAYEVGQRHAPRVLLADEVGLGKTIEAGMIIHQQLLAGRAERVLIVVPESLQHQWLVEMLRRFNLRFSLFDDSRYSEALLDSSNPFDTEQMVICSLDFVRRNKQRLEQLADASWDLLVVDEAHHMAWSEEAPSREYQVIEQLAEHIPGVLLLTATPEQLGQQSHFARLRLLDPDRFHDYEEFVNEQQKYRPIADAVTLLLGGERLTDDKLNLLGELIDEQDIEPLLKAANSQSEDSEAARQELVTMLMDRHGTSRVLFRNTRNGVKGFPHRVLHQIKLPLPTQYQTAIKVSGIMGAKKTLDARAKDMLYPEQIYQEFEGENATWWNFDPRVEWLLNYLVANRGEKVLVICAQAATALQLEQVLREREAIRAAVFHEGLSLIERDRAAAYFASEEDGAQVLLCSEIGSEGRNFQFACQLVMFDLPFNPDLLEQRIGRLDRIGQNREIQIMVPYLEDTAQAILVRWYHEGLDAFEHTCPTGRTIYDSSYQELISYLATPSEQEGLDEFIHTCRQQHEGLKLQLEQGRDRLLEMHSNGGEHGQELAQSIAEQDNDINLVSFALNLFDIVGINQEDRSDNLIVLTPSDHMLVPDFPGLPPDGCTVTFDREQALSREDAQFVSWEHPIIRNGLDLILSGDTGSCAVSLLKNKALPVGTLLAELVYVVEAQAPKHLQLTRFLPPTPVRMLMDRNGTNLAAQVEFESFNRQLNAVNRHTSSKLVNAVQQEVHTMLQQAEALVEAQAQALIETAKREADDKLSTELARLEALKAVNPNIRDDEIEALEHNRKMVLENLNQAGWRLDAIRLVVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: ENGB_THEAB
Sequence: MKIKSVELVKTIYKSNDKYPESLNGEFVFVGRSNVGKSTLLNILTGRNIAKTSKKPGKTASINFYKINNSFYFVDLPGYGYAKVSVEERARWRKIIENYFSKRAWNIKLVFVLIDGRHELQKNDEILLEWLKELELDFAIVMTKMDKLKNSERAKMIRYYKDLYGENYTIIPYSAITREGIDKIYELIEIFGGV
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: FL3H_HORVU
Sequence: MAPVSNETFLPTEAWGEATLRPSFVRDEDERPKVAHDRFSDAVPLISLHGIDGARRAQIRDRVAAACEDWGIFQVIDHGVDADLIADMTRLAREFFALPAEDKLRYDMSGGKKGGFIVSSHLQGEAVQDWREIVTYFSYPVKARDYGRWPEKPAGWCAVVERYSERLMGLSCNLMGVLSEAMGLETEALAKACVDMDQKVVVNFYPRCPQPDLTLGLKRHTDPGTITLLLQDLVGGLQATRDGGKNWITVQPISGAFVVNLGDHGHFMSNGRFKNADHQAVVNGESSRLSIATFQNPAPDARVWPLAVREGEEPILEEPITFTEMYRRKMERDLDLAKRKKQAKDQLMQQQLQLQQQQAVAAAPMPTATKPLNEILA
What is the function of this protein?
Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants.
What are the official names of this protein?
Naringenin,2-oxoglutarate 3-dioxygenase, FHT, Flavanone-3-hydroxylase, F3H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RS19_TRIL1
Sequence: MARSIKKGPFVDGHLMKKVETEGPNSKKIIKTWSRRSTITPEFIGVSLAVHNGKKFIPVFVTENMVGHKLGEFSPTRTFHGHAADKKSKVKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CCME1_XANOR
Sequence: MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMVKAGSIQRAADSLKVSFTVIDKNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE 1, Cytochrome c maturation protein E 1, Heme chaperone CcmE 1.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ISPD_NEIMA
Sequence: MKRKNIALIPAAGIGARFGADKPKQYVEIGSKTVLEHTIGIFERHEAVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLETGLAAETDNILVHDAARCCLPSEALTRLIEQAGNAAEGGILAIPVADTLKCADGGNISATVERTSLWQAQTPQLFRAGLLHRALAAENLDGITDEASAVEKLGIRPLLVQGDARNLKLTQPQDAYIVRLLLDAV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CAI19_CONGE
Sequence: MGMRMMFTVFLLVVLATTVVSFTSRRGPKSRRGEPVPTTVINYGECCKDPSCWVKVKDFQCPGASPPN
What is the function of this protein?
Does not show activity on all the human nAChR subtypes studied.
What are the official names of this protein?
Conotoxin G1.9.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRA2_CAERE
Sequence: MSLRSNKLLVAAVIFTVVTFGLLLTSSIFNNKTTTSLTYGGILPKFGQRIIEKKSNEEYIIEKIEHTQKDGEDVRSTRYLTHHSYLLRNLAKMEVKHHGKDFSINDICYKPHNAIFETTFAPENIDKLPNYLQRLILEAQRLSPCLIVTPLNCYHDSYRIHSEMSKWNTSNVTNFLNRKLRNSYIDAIGESEERPYIKSTYGPDLIKEWAHLMFKLPSKQTSSFSKKDLSSKIELWLSSIESKTNLTELGRPSEVDNYFDICTSMQQVHDFDERKRKFGLYDDDDEFLIGLDCVENKTKFIEWIQERELRGVSKPFNPNQQCDGIFKNSEGLEFFYGTRSFGNNTAPFDKMKTEIGLMTPEQILTTMLHSDFVNGFESIWTIERAQELLDDFRLAIRQEVKRFNENRSSLKIGIDTRVVQREESNETELEISSNLDSVVYFILFIRCVLLIFFAFFAWSVNPLRSAVMFLVRDALTSLLFSILCKSDGQIELNSELLGYIILLTIVNTYLTTRVSWYKDRNETCIQRAKDFPSRSNFSLLFSIDSLRENCDSRQLQYALAKLSKYLTALDTYSTETFMQLPNYWPFISILFVPITGCYWYFVDINLPKISVVLLPSFIVATIEQRQVEKSLLKERKAKKEFQKVQKKKMEKFLSDGAVDRLLSGNSESVEDKKLYKSKDCVIHKESAGRLYELSRSSYDVSKIMAYPNQRVRDFRFDALGCYFWLMKLKSAGILLYGSAVLFVLLSVAVMLIPIQRTSLQKDMNNEVYFGFSINNMSSDWANINKNLHAFNSEIDSIQSLQTISNWKKGFDRFEGRFYKNSSRISDANDYVEWMNQEPINWSVMAPLTRISPKFGIPSPFKFRFRYQIEVNNNESEVIDTVQRIDTLLTKYKGTLSSPIVDGVLYEYYHGNAAVWNSFVFNELLASGILSAFFALIVVIFSITPSISSVLIFSFFVIGSRLEIAAVISLFSLDNQQLYTDSAVLVGFLVAWAPFYELSLFRRRLLYKLKTRCTPELSSGKRIRPPFTKAVDTAQVFAIVLAASLIIAVVAGVVPEFQKFFWPTVILIVVQLVAFGNSIAVLVATNQMFEREVRNFLDNEFELGNGTTAGQVCHMAQKLIPPKYDIPIPMNDFHIRPTNMSKFYAPPPAKKRAKQTNNETDPEKKEDEPGTSNANNVSQEEAAHRLAILPWHFVLGGIPVDLTTRSDQIINGPFIGISSDAMRTHEINSELEDQDDYSSESSVEDVESDPAPEEEIKYHEENMLHMIEKVQKDAAEKEAKEKVHQVESAQRRAPNFDDPNVAGPSHRYQRNEERISTDIVPADPPREIPANPVPPPTHVLVQRAPRPHEMPPVIDRTIPRDPRTEPPNLQECIQQNDDPSLPPHPRRHQYPDHYGRAMISYCEDVYWTYNDGRLPPNVAMPPRPFDWHYRRVAPPEDFNYVPPPGQPSIPIPAEAMALREERARAHREQEQRDNSQSPSPSPEPGL
What is the function of this protein?
Plays a major role in controlling sexual cell fates.  Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote female development.  In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1.  Negatively regulates male development when bound to fem-3 and is required together with tra-1 for promoting spermatogenesis.
What are the official names of this protein?
Sex-determining transformer protein 2, Cr-tra-2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPEL_GEOSW
Sequence: MSSISPFVAIRRDLHKIPELGFQEFKTQQYLLRYIHALPQERLEIQTWKTGIFVKVKGTAPRKMIGYRTDIDGLPIKEETGLPYSSEHEGNMHACGHDVHMSIALGLLTHFAEHPIQDDLLFIFQPAEEGPGGAKPMLESEIMKVWKPDMILALHIAPEYPVGTIATKEGLLFANTSELFIDLKGKGGHAAFPHLANDMVVAACSLVTQLQSIVARNVDPLDSAVITIGKISGGTVQNVIAEHARLEGTIRTLSVDSMKKVKERIEAMVSGIKMAYQCEAEIDYGSMYHQVYNDPELTTEFIQFAENYQGIRFIRCKEAMTGEDFGYMLAEIPGFMFWLGVDSPYGLHHAKLTPNEAAIDQGISFLISYITWKGNN
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: UPP_ECO8A
Sequence: MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NDOR1_DICDI
Sequence: MNKKCTIIYATESGTSQEVAEKLSRDLVLYEIKPRLIDVTNYNKLELPMEKIVIFVLSTTGHGEVPDPMKPLWNFLLIKSLPSNSLANTKFAILGLGDSSYTTYNFAAKKLYQRLQSIGGTPLLRRGDADDQHDLGIDYEVEKWSQELISKLLTIYPLSPNFNINNIKNQLNKSKYNIKIDKINENNKEIKYEIPTQFYKSKLKVNKRITVEEWEQDVRHIELDISECKELQVPIKYQSGDVAYVLPKNPIKRVNEFIELLGLHSNWIIESIEPIDKEITQSPTLLKLPITIYDLVRCYFDIMGSPRRYFFELLSHFVTNPIEKERLEFFSSTEGQDDLRTYNQKEKRNYIDVLKEFPSIEIPFEYLFDLIPPIKPRPFSISSSSLLNPNTIHLTVGINTYTTPFRRLFRTGLCSQYFSSFLNDNDNNIVPIFIKESGARLPKSNEIPIIMVGPGTGCAIFRSFMQERLYFKNNSDNNNKLGDALFYFGCRSESKDYYYRDEFESNLEKGIISKLSVAFSRDGKDGKKVYVQQYIENDSDLIWDIINNRNGYFYISGSSGRMPKDVKQSLLTIIKSNLLKNNNNNNNNNNNNNNNNNNNNNNNNNDDENNIDEIVNNYFEKLEVEKRFITETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH oxidoreductase C, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7150_PRUMU
Sequence: MVWIWATIGLLALVHILQAWWKNKKKRLPPGPRGFPIFGSLHLLGEFPNKDLHRLARKYGDIMYMRLGLMPTIVISSPEAAELFLKTHDLVFASRPPHEGSKHISFGQKNLIFSEYGAYWRDTRKMCTIELLSNHKINSFKSMRREEVSLCVESIRAAANNRGVAVDLSDKVSSLSVDMSCRMVLGKKYRDEEFDERGFKSVVREAIQLASAPNLGDYIRFIAPLDLQGFTKRMKSVNKAFDNLFEKIIEEHLQPNDGERTMDFVDVMVGFMGSEESEYRIERPHIKAIMLDMLVASMDTSATTIEWALSELMRHPKAMKKVQKELENVVGLDKMVEESDLEKLDYLNMVVKETFRLHPVAPLLIPHASIEDCTVNGYHIPKKSRVLINVWAIGRDPNAWTDAEKFIPERFEGSSVDVRGNHFQLIPFGSGRRRCPGIQLGLTVVQLVLAQLVHCFDWELPNNMLPEELDMTEEFGLTVPRAKHLLAIPSYRLRKSA
What are the official names of this protein?
Cytochrome P450 71AU50.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PLSX_ANAD2
Sequence: MVGKIAPIAVDAMGGDHAPGAIVQGAVNAARKGLPVVLVGPEARVREELARHRAASSLPLEVHPATEVVEMHDHPGQAMRRKKDNSIRVCFDLVASGRAAGMVSAGNSGAVMAGAILVLGRPEGVERPAIVSVLPALKGAPLMLDMGAVVDCRPIHLVQFALMGEVYSRRVHGVTRPRVAILSNGEEDTKGTDLTRAAAAALRRAPIDFVGYCEGRDLLTGEVDVIVTDGFTGNVALKTMEGTAKVVGEYLKRALRSTTVSKIGGLLSRAALEGMKKRIDWREVGGAPLVGVNGVGFISHGRSDALAIENAIRRAGDAARTHFIDEIARAVAPSHALLEVPADGAATEQGPTPRRIAPPRT
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ACE1_HYPJE
Sequence: MSFSNPRRRTPVTRPGTDCEHGLSLKTTMTLRKGATFHSPTSPSASSAAGDFVPPTLTRSQSAFDDVVDASRRRIAMTLNDIDEALSKASLSDKSPRPKPLRDTSLPVPRGFLEPPVVDPAMNKQEPERRVLRPRSVRRTRNHASDSGIGSSVVSTNDKAGAADSTKKPQASALTRSAASSTTAMLPSLSHRAVNRIREHTLRPLLEKPTLKEFEPIVLDVPRRIRSKEIICLRDLEKTLIFMAPEKAKSAALYLDFCLTSVRCIQATVEYLTDREQVRPGDRPYTNGYFIDLKEQIYQYGKQLAAIKEKGSLADDMDIDPSDEVRLYGGVAENGRPAELIRVKKDGTAYSMATGKIVDMTESPTPLKRSLSEQREDEEEIMRSMARRKKNATPEDVAPKKCREPGCTKEFKRPCDLTKHEKTHSRPWKCPIPTCKYHEYGWPTEKEMDRHINDKHSDAPAMYECLFKPCPYKSKRESNCKQHMEKAHGWTYVRTKTNGKKAPSQNGSTAQQTPPLANVSTPSSTPSYSVPTPPQDQVMSTDFPMYPADDDWLATYGAQPNTIDAMDLGLENLSPASAASSYEQYPPYQNGSTFIINDEDIYAAHVQIPAQLPTPEQVYTKMMPQQMPVYHVQQEPCTTVPILGEPQFSPNAQQNAVLYTPTSLREVDEGFDESYAADGADFQLFPATVDKTDVFQSLFTDMPSANLGFSQTTQPDIFNQIDWSNLDYQGFQE
What is the function of this protein?
Binds to the promoter of the cbh1 gene and activates transcription.
What are the official names of this protein?
Zinc finger transcription factor ace1, ACEI.
What are the subcellular locations of this protein?
Nucleus.