PharMolix/UniProtQA huggingface dataset:
Protein: ADHB_BACSU
Sequence: MKAVTYQGIKNVVVKDVPDPKIEKSDDMIIKVTSTAICGSDLHLIHGFIPNMQEDYVIGHEPMGIVEEVGSGVTKLKKGDRVIIPFNIACGECFFCKNQLESQCDQSNDNGEMGAYFGYSGQTGGYPGGQAEYLRVPFANFTHFKIPESCEEPDEKLSVIADAMTTGFWSVDNAGVKKGDTVIVLGCGPVGLFAQKFCWLKGAKRVIAVDYVNYRLQHAKRTNKVEIVNFEDHENTGNYLKEITKGGADVVIDAVGMDGKMSDLEFLASGLKLHGGTMSALVIASQAVRKGGTIQITGVYGGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMFELVSTGKIDPGDVVSHVLPLSEAKHGYDIFDSKMDDCIKVVLKP
What are the official names of this protein?
Uncharacterized zinc-type alcohol dehydrogenase-like protein AdhB.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein: ITPA_ORYSI
Sequence: MSGAAARALPKAVTFVTGNAKKLEEVRAILGSSIPFQSLKLDLPELQGEPEDISKEKARMAASQVNGPVLVEDTCLCFNALKGLPGPYIKWFLEKTGHEGLNNLLLAYEDKSAFAMCIFSLALGPGEEPMTFVGKTAGKIVPARGPADFGWDPVFQPDGFDQTYAEMPKSVKNQISHRGKALALVKEHFAAANYKVQNDGSA
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_AFIC5
Sequence: MQNSQAESWHGTTILTVRKGGRVVIGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLEAKLEQYPGQLTRACVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEDGVMAIGSGGNYALAAARALSDSEHDAETIVRRSLEIAADICVYTNRNVTIEALTA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I10R1_MOUSE
Sequence: MLSRLLPFLVTISSLSLEFIAYGTELPSPSYVWFEARFFQHILHWKPIPNQSESTYYEVALKQYGNSTWNDIHICRKAQALSCDLTTFTLDLYHRSYGYRARVRAVDNSQYSNWTTTETRFTVDEVILTVDSVTLKAMDGIIYGTIHPPRPTITPAGDEYEQVFKDLRVYKISIRKFSELKNATKRVKQETFTLTVPIGVRKFCVKVLPRLESRINKAEWSEEQCLLITTEQYFTVTNLSILVISMLLFCGILVCLVLQWYIRHPGKLPTVLVFKKPHDFFPANPLCPETPDAIHIVDLEVFPKVSLELRDSVLHGSTDSGFGSGKPSLQTEESQFLLPGSHPQIQGTLGKEESPGLQATCGDNTDSGICLQEPGLHSSMGPAWKQQLGYTHQDQDDSDVNLVQNSPGQPKYTQDASALGHVCLLEPKAPEEKDQVMVTFQGYQKQTRWKAEAAGPAECLDEEIPLTDAFDPELGVHLQDDLAWPPPALAAGYLKQESQGMASAPPGTPSRQWNQLTEEWSLLGVVSCEDLSIESWRFAHKLDPLDCGAAPGGLLDSLGSNLVTLPLISSLQVEE
What is the function of this protein?
Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well.  In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively associated with IL10RA and IL10RB respectively.  These kinases then phosphorylate specific tyrosine residues in the intracellular domain in IL10RA leading to the recruitment and subsequent phosphorylation of STAT3 (PubMed:8910398).  Once phosphorylated, STAT3 homodimerizes, translocates to the nucleus and activates the expression of anti-inflammatory genes.  In addition, IL10RA-mediated activation of STAT3 inhibits starvation-induced autophagy (By similarity).
What are the official names of this protein?
Interleukin-10 receptor subunit alpha, IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA, CDw210a, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R1.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: ADML_PIG
Sequence: MKLVPVALMYLGSLAFLGADTARLDVAAEFRKKWNKWALSRGKRELRLSSSYPTGIADLKAGPAQTVIRPQDVKGSSRSPQASIPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDGVAPRSKISPQGYGRRRRRSLPEASLGRTLRSQEPQAHGAPASPAHQVLATLFRI
What is the function of this protein?
AM and PAMP are potent hypotensive and vasodilatator agents.
What are the official names of this protein?
Pro-adrenomedullin.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_LEGPA
Sequence: MSIDTIVAIATPPGRGGVGIVRISGPKAYAIALCLNGNKALQPRLATFCSLYKGNNEVLDQGLVLYFKGPHSFTGEDIIEIQAHGSPVVLDLLIKESIAAGARLARPGEFSERAFLNDKIDLIQAEAIADLIQASSDTAARMALKSLQGDFSKKINQLNEELIYLRMYVEAAIDFPEEEIDFLNDGNVSQLLQRIIGRLEEIRSQANQGVLLREGLSLVIAGRPNAGKSTLINNLAGRDVAIVTEIAGTTRDIMREHILLDDIPLHIIDTAGLRDSDDLVEKEGIKRAWQELKRADCVLLVVDINNRDQQNSLLNELRLTLPNKIPIITVYNKIDTTKLTAKCDEHTVYLSAKTGEGLDELKKVIKQVVGYQPTEGQFLARRRHLQALDEAKALLLTGQSQLTNHKAGELLAEDLRLAHQTLCEITGEFTSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_LEPIC
Sequence: MKIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWHRDGLDKKYELVILPGGFSYGDYLRSGAMAGFSPVMKSVKEHVDKGGKLFGICNGFQILTEAEYLPGALIRNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADGCYYATSDVLKQLEDEDRILFRYSGENPNGSLDSIAGITSKNFKIVGMMPHPERAMNPITGEMDGKVVLDLILGS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTEG_XENLA
Sequence: MFSLQHVLLILISLGQVYSQQVHHNAGRKFPQWLTGLIAMTVFLFLVLVVYVAKMFWDKRSQESINMKDIEEVVANGTSECCEARKENQYISCNMKDLRSSEHIHAYENPIEVNDNVRSTAM
What is the function of this protein?
Essential for pronephric tubule development, acting upstream of pax8 and lhx1/lim1 and downstream of retinoic acid signaling to induce pronephric mesoderm to form pronephric tubule-specific cells.
What are the official names of this protein?
Proximal tubules-expressed gene protein, Xpteg, MAP17-like protein, PDZK1-interacting protein 1-like.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TREP_THEBR
Sequence: MANKTKKPIYPFEDWVIRETQFSIDTNYRNETIFTLANGYIGMRGTFEERYSGPKNTSFNGTYINGFYEIHDIVYPEGGYGFAKIGQTMLNVADSKIIKLYVDGEEFDLLQGKILFYERVLDMKKGFVERKVKWESPTGKILEVKIKRIVSLNRQHLAAISFTMQPVNFTGKIRFVSAIDGNVSNINDSEDVRVGSNLKGKVLKTIDKSVEGLKGWIVQKTQKSNFSYACAIDNVLVADSKYEVSNSLEEDGVKVIVDLEAEKGTSYTLNKFISYYTSKDFDENKLVALALEEIEKAKNDGFETIEKEQEEFLNSFWKDADVIIEGDKALQQGIRFNEFHLLQSVGRDGKTNIAAKGLTGGGYEGHYFWDSDIYIMPFFLYTKPEIAKALVMYRYNLLDAARSRAKELGHKGALYPWRTIDGPECSAYFPAGTAQYHINADIVYALKRYVEATNDVDFLYDYGCEILFETARFWEDLGAYIPLKGNKFCINCVTGPDEYTALVDNNAYTNYMAKMNLEYAYDIANKMKKEVPQKYQKVASKLNLKDEEIVAWKKAADNMYLPYSKELDIIPQDDSFLYKERITVDEIPEDQFPLLLHWHYLNIYRYQICKQPDVLLLMFLQREKFTKDELKKNYDYYEPITTHDSSLSPAIFSILANEIGYTDKAYKYFMMTARMDLDDYNDNVKDGIHAASMAGTWSAVVNGFGGMRVYTNELHFEPRLPKEWNLLSFNVRYKGRKINVKLTKENVVFALLEGEPIEIYYFDKKILLEKGEIK
What is the function of this protein?
Catalyzes the reversible phosphorolytic cleavage of trehalose.  Phosphorolysis is specific for trehalose, but D-xylose, D-galactose, L-arabinose, D-fucose, L-fucose, D-glucosamine and 2-deoxy D-glucose can act as substitutes for D-glucose in the synthetic reaction.
What are the official names of this protein?
Alpha,alpha-trehalose phosphorylase, TPase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 65 family.
Protein: NUSB_BUCAI
Sequence: MKPSFRRKARACALQVLYSWEISHNNIKESAIYFLKEKNKKNIDIVYFYELIIGITYDCKNIDNLMKPYLFRSLKELGHIERAILRISFYELHKRNDIPYKVSINEGIELAKLFGSEDSHKFINGVLDKAVFKMGYNKKVVIA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: 11S1_MACIN
Sequence: LSTLNTHNLPLLRLVYLEREDLVAVHVDDLNNQANQLDQKLDGGLLPQGHAPHWLMNAHSLFYLTRLLVAQCRAPKGMLVVLPAGVAHWCLNDGKHYLDNPR
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Legumin-like protein Mac i 2, 11S globulin seed storage protein Mac i 2.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: TAR1_COLES
Sequence: MAKLLLFLLPAILGLLIPRSAVALGTNYLLSGQTLNTDGHLKNGDFDLVMQNDCNLVLYNGNWQSNTANNGRDCKLTLTDYGDLVIKNRDGSTVWRSRAKSVKGNYAAVLHPDGRLVVFGPSVFKNDPWVPGLNSLAFRNIPFTDNLLFSPQVLYGDGRLTAKNHQLVMQGDCNLVLYGGKYGWQSNTHGNGEHCFLRLNHKGELIIKDDDFKTIWSSSSSSKQGDYVL
What is the function of this protein?
Mannose-specific lectin.  Shows agglutinating activity towards erythrocytes from rabbit.
What are the official names of this protein?
Mannose-specific lectin TAR1, Agglutinin, Tarin.
What are the subcellular locations of this protein?
Secreted.
Protein: VGA_BPG4
Sequence: MFKVHSDYFSKPNIDAIKPLVETAGMSVLTQSPNLRIWKQCNTRIKLLEEILAHYTNGIRRDDNGDFWMNPNSQLATTIAYRAHHKGHNPKFKQYPETFTLDDIITGKPIPQTAPDELQLSDEIVEDYRLTVLSIIEELQECYDVLGQLDINNTIDHKPLGNDHWNLLYEKPVYKHWYQLVSNRPLKDIRADYNYAKAKGVKDECSKILEESTMKSRRGFTVQRLMNAMRTAHSKGWYVVFDTLTLADDRLKDFYDNPNALRDYFRDIGRMVLTAEGRSVHDSSSDCYQYFCVPEYGTQHGRLHFHAVHLMRTLPLGSLDPNFGKLVRINRQINSLQNTWPYGYSMPIAVRYSQDAFSRAGWLWPVDSKGEPLKATSYMAVGFYVAKYVNKKSDIDMAVKGLGNKEWNNSLKTKINLIPKKVFRIRMSRNFGMKLLSMAHLSAETLMELTQVGYDVTPFNNILKQNAKKELKSRLAKKSVADVLEAQPVTTNLLKFMRNLTRTIGASNLQSFIASMTTKLTSTDISDETKNYVASAGIAVANLRIKSKWTAGGK
What is the function of this protein?
The A* protein binds to double-stranded DNA and prevents their hydrolysis by nucleases.
What are the official names of this protein?
A protein, GPA.
Protein: EX7L_RHIL3
Sequence: MSNVFDGDSPTNLAEYSVSELSGSIKRTVETAFDQVRVRGEISGYRGPHSSGHAYFALKDDRARIDAVIWKGTFSRLKFRPEEGMEVIATGKVTTFPGSSKYQIVIETLEPAGAGALMALIEERKRKLGAEGLFDAARKKRLPFMPGVIGVVTSPTGAVIRDILHRISDRFPVHVLVWPVKVQGEGSGEEVANAIRGFNALEPSGTIPRPDVLIVARGGGSLEDLWSFNDEIVVRAAAESAIPLISAVGHETDWTLIDYAADVRAPTPTGAAEMAVPVKAELEAQAAGLAARLQGCMNRQMDQRRQSVRALMRALPSLDQLLALPRRRFDEAATGLGRGLELNTINKRRGFERVAAHLRPDLLAGRIAERRQTLNERMARAERMVERLIDRSKSRVDRAEAILASLPARLKTQTDRGRERLGNLSRHADTAVRHQLTRARSELSAQDRVLQSLSYKNVLKRGYAVIRDEDNRPVSQAAHLSAGMGIAIEFADGRVGAMTTEGGTPPAGAKKRSTKPAEPPKQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB25_TOBAC
Sequence: MAAATMALSSSSFAGKAVKLSPSSSEITGNGKVTMRKTVTKAKPLSSGSPWYGPDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWACQVVLMGAVEGYRVAGGPLGEVVDPLYPGGSFDPLGLAEDPEAFAELKVKHIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWSYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 50, chloroplastic, LHCII type I CAB-50, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: RIMP_LEPBL
Sequence: MTVSREEISTILDDALFLPVKLYSLKVNQRPNHSLIEVVLDNLEHPYGSVSLLECEQVSRKLKEELERISPDLDFTLKVSSAGAERKLHLPEDIDRFRGIPVRLVFRSGESEKNQEGIFRIVNRDGDQVFLEKFQKGKKSAVKKQTTLNLKDILKGNLYVSI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MICA1_HUMAN
Sequence: MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELALGTGAQG
What is the function of this protein?
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization (PubMed:29343822).  In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2) (PubMed:21864500, PubMed:26845023, PubMed:29343822).  Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments.  Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.  Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections.  Through redox regulation of the actin cytoskeleton controls the intracellular distribution of secretory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity).  May act as Rab effector protein and play a role in vesicle trafficking.
What are the official names of this protein?
[F-actin]-monooxygenase MICAL1, Molecule interacting with CasL protein 1, MICAL-1, NEDD9-interacting protein with calponin homology and LIM domains.
What is the protein family that this protein belongs to?
Belongs to the Mical family.
Protein: TATA_BACC0
Sequence: MFSNIGFPGLILILVAVLILFGPKKLPEIGKALGETLKEFKKSTKELTDDAFQEKEKKEKM
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MSBA_CUPPJ
Sequence: MSNPAKSEQSAGHDVKVGKRLMGYLRPELRIFIAAILAMAVVAASEGVIPKVVNDLLDKGFGGEYAGKLWHVPAILTGVALIRGVAQFASGYLLSLISNRVLLKMRMQMFDRMLHAPAHFYHRNTAASLINAVIFEVNQVLSILTSVFITLVRDSLTVVALLIYLFYTNWRLTLIVSVILPVIGYLMSKINRRLRRLNRDHQTLTNSAAYVVEEAAGGYKVVKLHGGEAYEMNRFRNMADRLKNYSMRMAVAGGLNQPVTAFLAALALSVIITIAMIQAQGNQTTIGGFTGFVMAMLLLISPLKHLTDINQPLTRGLTAAELIFRLIDEPVEPQDGGVRLERAKGDLVFERVGFRYGEGTRPALEGIDIRVPAGEVVALVGPSGSGKTTLVNLVPRFFDPTDGRILLDGHAIGDIALRELRNQIAFVSQDVVLFNDTVAANVAYGARSEEEIDMARVERALQAAYLTEVVKNLPEGVNTNIGDNGMKLSGGQRQRLAIARAIYKDAPILILDEATSALDSESERQVQAALEALMVGRTTLVIAHRLSTIENADRIVVLDHGRVAEHGTHEELLAANGLYAGLHRIQFATH
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPL15_ORYSI
Sequence: MQREVGPQVAPPMFLHQIQPLPPHATAAKKRGNPWPAAAVAAAEAKGGGNWNPRMWDWDSRALTAKPSSDALRVNAGLSHHQQQQQQSPPAAAKAAEALRQGGGGSGGLNLQLGLREDAATPMDVSPAATTVSSSPSPPASSAPAQEPVVRPSKRVRSGSPGSASGGGGGGGGGGNSGGGGGSYPMCQVDDCRADLTNAKDYHRRHKVCEIHGKTTKALVGNQMQRFCQQCSRFHPLSEFDEGKRSCRRRLAGHNRRRRKTQPTDVASQLLLPGNQENAANRTQDIVNLITVIARLQGSNVGKLPSIPPIPDKDNLVQIISKINSINNGNSASKSPPSEAVDLNASHSQQQDSVQRTTNGFEKQTNGLDKQTNGFDKQADGFDKQAVPSTMDLLAVLSTALATSNPDSNTSQSQGSSDSSGNNKSKSQSTEPANVVNSHEKSIRVFSATRKNDALERSPEMYKQPDQETPPYLSLRLFGSTEEDVPCKMDTANKYLSSESSNPLDERSPSSSPPVTHKFFPIRSVDEDARIADYGEDIATVEVSTSRAWRAPPLELFKDSERPIENGSPPNPAYQSCYTSTSCSDHSPSTSNSDGQDRTGRIIFKLFGKEPSTIPGNLRGEIVNWLKHSPNEMEGYIRPGCLVLSMYLSMPAIAWDELEENLLQRVNTLVQGSDLDFWRKGRFLVRTDAQLVSYKDGATRLSKSWRTWNTPELTFVSPIAVVGGRKTSLILKGRNLTIPGTQIHCTSTGKYISKEVLCSAYPGTIYDDSGVETFDLPGEPHLILGRYFIEVENRFRGNSFPVIIANSSVCQELRSLEAELEGSQFVDGSSDDQAHDARRLKPKDEVLHFLNELGWLFQKAAASTSAEKSDSSGLDLMYFSTARFRYLLLFSSERDWCSLTKTLLEILAKRSLASDELSQETLEMLSEIHLLNRAVKRKSSHMARLLVQFVVVCPDDSKLYPFLPNVAGPGGLTPLHLAASIEDAVDIVDALTDDPQQIGLSCWHSALDDDGQSPETYAKLRNNNAYNELVAQKLVDRKNNQVTIMVGKEEIHMDQSGNVGEKNKSAIQALQIRSCNQCAILDAGLLRRPMHSRGLLARPYIHSMLAIAAVCVCVCVFMRALLRFNSGRSFKWERLDFGTI
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 15.
What are the subcellular locations of this protein?
Nucleus.
Protein: MENG_STRGG
Sequence: MTRASLEKQPHEVASMFDGVAANYDLTNDVISLGQARLWRRAVAAAVDARPAQKILDLAAGTATSSQPFVKAGAYVVPCDFSLGMLKVGKERHPWMPFTAGDGMRLPFKDETFDTVTISFGLRNIQDTEVALRELYRVTKPGGRVVICEFSQPTWTPFRTVYTEYLMRAIPPAARAVSSNPDAYVYLAESIRDWPDQPALAALLQKAGWSKVAWRNLTGGVVALHRATRA
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RNH2_CLOBK
Sequence: MNLNNLENIRYNEIKEFSDKIKKEFTFFQKKQVMDIIEKLNKDPRKNVIKLGQALEKFLNKYEEELKRTNNMYNFDRRYGNNYLIAGVDEVGRGPLAGPIVAAAVVLDLNVEEMQRIFNIKDSKKLSEKKREELDIIIREKAISYNIALVDNKTIDERGISWSNNEVLKRAVEGLKVKPDLVLSDGYAVKNLNIRNEFIIKGDSKSISIASSSIIAKVYRDNMMKEYSKGLNMYGFNHNAGYGTEEHVQAIKKYGPSKIHRMSFLTNIL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSID_ECOL5
Sequence: MRLFNWRRQAALNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVLGSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGTVSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBA_NICTO
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TSAD_PHOPR
Sequence: MRILGIETSCDETGVAIFDDEQGLLSHELYSQVKLHADYGGVVPELASRDHVKKTIPLIKEALKKAGLTPADLDGIAYTAGPGLVGALLVGATIGRSLAYSWGLPAVAVHHMEGHLLAPMLEDNAPDFPFVALLVSGGHTMMVEVQGIGEYQILGESVDDAAGEAFDKTAKLMGLDYPGGPLLSKLAEKGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQEAVVDTLAIKCKRALKQTGLKRLVIAGGVSANSYLRQELGSLMTKLNGEVFYPRTEFCTDNGAMIAYAGMQRLKNQELMDLSVKAYPRWPIDQLKPLNK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.