PharMolix/UniProtQA huggingface dataset:
Protein: DBP10_USTMA
Sequence: MAKTIDFLASDGEDNFAARTISATSKPNRNDATASSSKPQKRARRSTKGSDDDGNDDFDIASSLLASAAEPAAVGMLSSSQQASQKAYASRVSAKDDDDDDARFIASVMQHANIKAGLEVAKKALSGKNKGKNKLGSGVVTGGGSFQSMGLHPSLLRSLLIRGFTTPTPIQRQAIPAIMSQPPRDVVGMARTGSGKTLAYLIPLINRLNGRHSPTFGIKSLILCPSRELAVQILRVGKEIARGWKADAGEGQDSRGEAIRWAIIVGGESLDEQFGIMSNNPDVVIATPGRMLHLTVEMNLDLKSVEYVVFDEADRLFEMGFAEQLEEMLLRLPPTRQTLLFSATLPKKLVEFTKAGLQANPKLVRLDADSKISADLRMAFFSVKPSEKEAALLVLLRDVIGVPLGEQAARDLDEEAQFNEDASDNQADGQRSRGYGNRRAEFKGKTKDKHLGNKRKRGGPGGALELLPHQTIIFCATKHHVEYLLLLLTTTGYACSHIYSSLDQATRGIQMSRFRRGQNSLLIVTDVAARGIDLPVLEHVVNFDFPPQPRTFVHRVGRTARAGRNGWAWSMCTNAELPYLCDLQLFLARPLVSSHTAIAALANGRDVASADALGLHDSLILGTLPREALDLETEFISSSLTNTSSSTAHDFPALRAVADRAQQKYEKSIAKASQESHRRAKEMVKLGSIEQINIRTASGREGQVPEWTLAGSPLEEMAVHDVVKRPEVYGLNRANKADAVTSALGSDRMDDKVKRGTDNALKEADEAAKRAALLAKVNAFRPQETVFEIGIRGDATPLGALMRSRRQTMQVKTKRAEALEARKRAIEGGGDAMEDDEEVTKPKVAARNKGKKKATAGKADNDEAVVGDAMVDMEQADEADILAAFDTTKPSKAQVQREALTDSETDASESDRDAASARHTKRARTKKAAPTSYRDPNFYLSYEQQGSTSERGYSLNNARSHTDSFIQQASAVSFDLAGDDATLGTQSQRPNVTRWDSKKKNFIQATVGADNKKMIRTESGVRLPASFRSGRYEDWKREKRIDMPKTGEIESNNHRVHERSPPETSVMGLKRFRHTKLSAPKTAGVFGNRRPGQPKRQAAKDEVKSARQIQKDRELKEKRREKNARPSKSDTNRRAKRGAARRGRGGHGPRGASR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YAAI_SHIDS
Sequence: MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: RLMKL_PSEU2
Sequence: MSDRYELFLTCPKGLEGLLAEEATALGLQETREHTSAIRGSADMETAYRLCLWSRLANRVLLVLKRFPMKDAEDLYHGVLDVEWQDHLESDGTIAVEFSGHGSGIDNTHFGALKVKDAIVDKLRTPDGERPSVDKINPDLRVHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAILIRAGWPRIAAEGGALADPMCGVGTFLVEAGMIAADIAPNIKRERWGFSAWLGHVPALWRKLHDEALARAEAGLAKTPSWIRGYEADPRLIQPGRNNIERAGLSDWIKVYQGEVATFEPRPDQNQKGLVICNPPYGERLGDEASLLYLYQNLGERLRQACLNWEAAVFTGAPDLGKRMGIRSHKQYSFWNGALPCKLLLIKVTPDQFVTGERRTPEQRQIERENPVEVEVVERKLNKNGNPIKPEPVVVEQARLSEGGQMFANRLQKNLKLMGKWVRREGIDCYRVYDADMPEYSLAIDLYHDWVHVQEYAAPKSIDPEKASARLFDALAAIPQALNIDKNRVVIKRRERQSGTKQYERQSAQGQFLEVSEGGVKLLVNLTDYLDTGLFLDHRPMRMRIQREASGKRFLNLFAYTATASVHAAKGGARSTTSVDLSRTYLDWARRNLSLNGFSDKNRLEQGDVMAWLQANRDEYDLIFIDPPTFSNSKRMEGIFDVQRDQVELIDLAMARLAPGGVLYFSNNFRKFVLDENLSQRYAVEDITAHTIDQDFARNGKIHRAWKIMARS
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_RHIE6
Sequence: MPTVNQLIRKPRQANVKRNKVPALQENPQKRGVCTRVYTTTPKKPNSALRKVAKIRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RSMH_GEMAT
Sequence: MTPVRSAPSGRTGTYHVPVLLSEIETMLANATTVLDCTLGGGGHTAAFLERGVRVTGVDRDPRALAAARERLGEYERSGQFRAVLANYAALEEAGFSTDDRFDGILLDLGVSSHQFDDASRGFTFREGAPLDMRMGTDADLDAGELLNTIDEVDLSALLRAYADEPRAARMAREIVRRRERRPFATADDLVDAIRAVLGPRSGAPDFARIFQAVRIAVNDELSGLERALPALRDRLTPGGVLAIISYHSGEDRLVKNAFRDWSASCVCPPRQFVCTCRGRPLGDTITRKPVSATEQEIDQNTRARSARLRAWRSA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CQ054_HUMAN
Sequence: MTSSAPTLPDVTIRNVSRHIQMSLMGKGEPPWLCRLQLEPLLQAMEEQQLGNLEARWEVEKHGNEVSGSTSREVWEDADFICPVLKQCTNPKLNENKNIHQAKECEKSPFLSLSPHQQWKPGLPRRNDALPTSLCLCCSEN
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00469.
Protein: CADH2_RHIFE
Sequence: MCRIVGAPRTLLPLLAALLQASVEASGGIALCKTGFPEDVYSAVLSQDVHEGQPLLNVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPNLPEDSVKESQEIEEIVFPRQLMKHNGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDDDDPNTLNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYMLIIQATDTEGSPTYGLSNTATAVITVTDVNDNPPEFTAMSFYGEVPENRVDVIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMPQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVVPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRLDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD
What is the function of this protein?
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell.  Cadherins may thus contribute to the sorting of heterogeneous cell types.  Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence.  Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity).  CDH2 may be involved in neuronal recognition mechanism.  In hippocampal neurons, may regulate dendritic spine density.
What are the official names of this protein?
Cadherin-2, Neural cadherin, N-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Note=Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes (By similarity). Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes (By similarity).
Protein: DABA_BACAC
Sequence: MSIPSILRKETLKKKDKNIDLQENNINDLVVSASRVIAPLWPISTFAAHHPWMGLEKQSFEQVANWLKEARNVDIYPSASMIHSAKAKGEIEESFLQIALSRWLDSQSFHMPRETAERFCQEALKLERLPSSLLSSPELNKLAEEINYVNTGSMKDSSMQPISSLIENQNGDNLSDILNYHIIKWCKLYLDDAGASWAMPNREKGFYRAWQHLITFDPALSKTERKVLKDWPEDALIALTKALSELGISESNMQAYLEGHLLSLPGWAGMIRWRSQQSIEEQELLIEYLAVRLSMELAIVKPYLPLKNQKVEKKVSIVPLIASWIYWGDISIEKWLQMSATEQSELLAFAYRFDENTRKKLWLEAWEQTHAEQLREKIASKQRATHDKKRVVAQLAFCIDVRSEPFRRHLEKLGPFETFGIAGFFGLPIATTELGSNDSHPSLPVILKPKHQIKELTDENECKSYEQRKMVGSSVRYTFKTMKQNVLTSMLLPEVSGPLLGLQMVTRSFVPRRVGGFIRNLRKNMLQKPDTTFSLNHVHDTNCEIPIGFTKEEKVNYVRQTLKMVGLTEGFAPLVVMCGHSSQSTNNPYAAALECGACGGAAGGFNARVFATLCNLPEVREALSAEGIKIPDDTIFAAAEHKTTVDELEWIYVPELSETAQEAFDCIEAIMPNVSQHANRERLMQLPHFKTKIKNPSKEAHRFAEDWSEIRPEWGLARNASFIIGQRELTQECDLEGRAFLHNYDWKQDESGDILANIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLPGLPWQSVMQSDRETYHSPLRLLIVIQAPTKYIERLLNNNFTFREKVQNGWVRLASVDPEGRWKNW
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYL_TROWT
Sequence: MHALRALDTLCENMEYNFRALEEKWAPIWERDRLFEVDENDSETPRKYVLDMFSYPSGDLHMGHAETYAYGDFIARYWRHRGYNVLHPVGWDSFGLPAENAAIKHGSDPKVWTYRNIDQQARSMRLYAASFDWSRRLHTSDPEYYRWNQWLFLKLYKHGLAYRKKAWVNWDPSDRTVLANEQVLPDGTSERSGALVVKKKLTQWFLRITAYADRLLDDLSMLENNWPERVITMQRNWIGRSEGVSIEFNIPTLKRPVTVFTTRPETIFGVTYLALAFDSEVTEELASKSGVLGELLELRHNIDKTHEGVRGLDLKSFAIHPLTGQSVPIFAASYILSDYAKGAVMSVPGHDTRDERFAVRYNLPIVKIMEDNRLISSGKYSGQSVTQARENITRDLCAKSLGRREISYRLRDWLISRQRYWGTPIPILYDSNGSEIPVEEDDLPVLLPDSEGIDLTPSGLSPLGGIHDWVNLHKAGSLFRRDTDTMDTFFDSSWYFLRYLNPDCDTAPFTLEKAKKWGPVDQYCGGVEHAVLHLLYARFITKFLYDIGFVDFKEPFLRLINQGMVVLNGAKMSKSKGNIVEFSKEVSQHGVDVIRFALIFSGPPEEDIDWKDVSMTGAARFLSRCIQTAKEVPKRTADLSLGDIELRKHTHSLLNDIDWLVDSYRFNVIAARLMDLLNITRKKIQTIGADNPAIREAIETIAIALDMFSPYTAEEMWEILGNKYSVSKALFPEVDTTFLEQKTTCAIVQIDGRLRGRLNVLTNITTEQLVHSARSLPAIEHALSGRSVKRVICVPPKLVNFVVEPK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPC_ECOLX
Sequence: MKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLPGQYLLDVIVNGQSISPASLQISFVEPALSGDKAEKKLPQACLTSDMVRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNFTWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDSMVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSERNYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSASRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSYYRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK
What is the function of this protein?
Involved in the export and assembly of pili subunits across the outer membrane.  Forms a hexameric ring-shaped pore in the outer bacterial membrane.  The 2 nanometer-diameter pore allows the passage of the thin tip fibrillum.  As for the rod, it probably unwinds into linear fibers which would therefore be narrow enough to pass through the pore.
What are the official names of this protein?
Outer membrane usher protein PapC.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CLPX_BRUO2
Sequence: MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSAGMA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: TR10A_HUMAN
Sequence: MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNIWVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
What is the function of this protein?
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518).  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789).  Promotes the activation of NF-kappa-B (PubMed:9430227).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft. Cytoplasm, cytosol. Note=Palmitoylation is required for association with membranes.
Protein: KPB1_HUMAN
Sequence: MRSRSNSGVRLDGYARLVQQTILCHQNPVTGLLPASYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAKAYELEQSVVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDATSVYLLFLAQMTASGLHIIHSLDEVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNASSVGMAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQSILNSLLPRASTSKEVDASLLSVVSFPAFAVEDSQLVELTKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKLFENIECEWPLFWTYFILDGVFSGNAEQVQEYKEALEAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKLPHMWGQSLYILGSLMAEGFLAPGEIDPLNRRFSTVPKPDVVVQVSILAETEEIKTILKDKGIYVETIAEVYPIRVQPARILSHIYSSLGCNNRMKLSGRPYRHMGVLGTSKLYDIRKTIFTFTPQFIDQQQFYLALDNKMIVEMLRTDLSYLCSRWRMTGQPTITFPISHSMLDEDGTSLNSSILAALRKMQDGYFGGARVQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDDNYDYLESGNWMNDYDSTSHARCGDEVARYLDHLLAHTAPHPKLAPTSQKGGLDRFQAAVQTTCDLMSLVTKAKELHVQNVHMYLPTKLFQASRPSFNLLDSPHPRQENQVPSVRVEIHLPRDQSGEVDFKALVLQLKETSSLQEQADILYMLYTMKGPDWNTELYNERSATVRELLTELYGKVGEIRHWGLIRYISGILRKKVEALDEACTDLLSHQKHLTVGLPPEPREKTISAPLPYEALTQLIDEASEGDMSISILTQEIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHHILSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSISAESQSPGTSMTPSSGSFPSAYDQQSSKDSRQGQWQRRRRLDGALNRVPVGFYQKVWKVLQKCHGLSVEGFVLPSSTTREMTPGEIKFSVHVESVLNRVPQPEYRQLLVEAILVLTMLADIEIHSIGSIIAVEKIVHIANDLFLQEQKTLGADDTMLAKDPASGICTLLYDSAPSGRFGTMTYLSKAAATYVQEFLPHSICAMQ
What is the function of this protein?
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.  The alpha chain may bind calmodulin.
What are the official names of this protein?
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform, Phosphorylase kinase alpha M subunit.
What is the protein family that this protein belongs to?
Belongs to the phosphorylase b kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: TSE7_PSEAE
Sequence: MANEVYANNMEISCKAANGKSIAAFPDVCFTPPQAPPTPLGVPIPYPNTGLSKDTTKGTRTIRITRKEVMLKNKSYYKTSYGDEPGRAPKKGIVTSKIKGKVYFTSWSMNVKFESKNVVRHLDLTTHNHASFPGNTPVWPYLDQATVDAGGGPCSNEVKKEKKDCADFKPHGSKDACAGLGAGKPSGKKTSNEADRLADKVAARKCLTARRCALQPYKPNSCCPQQTAHHLIEASALHDKGRGGKGSVPLKGISNYSENKAPCVCAEGVNQNVGTHGLMHTFQSAAAAKSRSGTLQLSNGSSISAKKTTYGTAKRQSMAAMGKVFPQSKCSKECLSAQLDNYHKQCGINARTPIKAVETGQTDVTAATQAIKTRNARLGATRSRVR
What is the function of this protein?
Type VI secretion exported toxin that via to its DNase activity induces growth arrest and ultimately DNA degradation within target cell (PubMed:30455305).  The activity is initially neutralized by a cognate immunity protein Tsi7 (PubMed:30455305).
What are the official names of this protein?
DNase toxin Tse7.
Protein: MTPS1_PINBN
Sequence: MALVSAVPLDSRLCLCRTLFGLTHELKAIRRTIPNLGMCRGGKSIAPSMSMSSTTFVSSEDGVPRRIGGHHSNLWDDDSIDSLSTSYEAPSYRERADRLIGEVKDMFHLISVEDGVSTSPLNDLHHRLWMVDSVERLGIDRHFKNETNAALDHVYSYWTEKGIGRGRESGATDLNSTALGLRTLRLHGYMVSSHVLDHFKNEKGQFACSAIQTDGEIRDVLNLFRASLIAFPGEKIMEEAEMFSTMFLKDALQKIPPSGLSQEIEYLLEFGWHTNLPRMETRMYIDVFGEDTTFETPYLIRERLLELAKLEFNIFHSLVKRELQSLSRWWKDYGFPEITFSRHRHVEYYTLAACIANDPKHSAFRLGFAKICHMVTILDDIYDTFGTMEELELLTAAFKRWDPSSIECLPDYMKGVYMAVYDNINETAREAQKIQGWDIVSYARKSWEALFDAHMQEARWISSGYLPTFEEYLENGKVSFGSRLTTLEPMLTLGFPLSPRILQEIDFPSNFNELICAILRLRGDTQCYKADMARGEEASSVSCYMKDHPGITEEDAVNQINALVNNLTKELNWELLRPDSGVPISYKKFYFDIWRVFHYGYKYRDGFSVASIEIKNLVTRTVVETVPL
What is the function of this protein?
Monoterpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens.
What are the official names of this protein?
Monoterpene synthase like 1, chloroplastic, PbTPS-mono1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DDL_STRPC
Sequence: MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEMFDQRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB103_YEAST
Sequence: MTLRDSCTTSLKGGPRRFPLRNFSLFTFCKQRNNNKNDKIHLFMYCT
What are the official names of this protein?
Putative uncharacterized protein YBR103C-A.
Protein: CYSP1_HOMAM
Sequence: MKVVALFLFGLALAAANPSWEEFKGKFGRKYVDLEEERYRLNVFLDNLQYIEEFNKKYERGEVTYNLAINQFSDMTNEKFNAVMKGYKKGPRPAAVFTSTDAAPESTEVDWRTKGAVTPVKDQGQCGSCWAFSTTGGIEGQHFLKTGRLVSLSEQQLVDCAGGSYYNQGCNGGWVERAIMYVRDNGGVDTESSYPYEARDNTCRFNSNTIGATCTGYVGIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV
What are the official names of this protein?
Digestive cysteine proteinase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: VKT2L_BUNMU
Sequence: MSSGGLLLLLGLLTLWMELTPVSSKNRPPFCNLLPEPGRCNAIVRAFYYNSRPRKCLEFPYGGCGGNANNFKTIEECQRTCAG
What is the function of this protein?
Shows weak binding and inhibition of MMP-2 and shows an activity in inhibiting migration and invasion of neuroblastoma.
What are the official names of this protein?
Kunitz-type serine protease inhibitor PILP-2, Protease inhibitor-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: XGPT_ECO24
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FABI_RICBR
Sequence: MTTGLLQGKRGIITGIANNMSISWAIAQLARKHGAELCFTYQSEILEKRVKPLAEEVGCNFVSELDVTNPESITNLFAEVKEKWGTFDFLLHGMAFSDRNELKGRYIDTSLGNFNNSLHISCYSLVELAREAEKLMNDGGSIVTLSYYGAEKVIPNYNVMGVAKAALEASVRYLANDMGENNIRVNAISAGPIKTLSGSVIGDFNSMLRSHAATAPLKRNTLQQDVAGAAVYLFSQLASGVTGEIHYVDCGYNVMGSNKIVG
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: HMUV_ECO57
Sequence: MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLFLDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCILHDLNLAAHYADRVVLMQKGKVIANGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PLPP2_BOVIN
Sequence: MERRWVFVLLDVLCVLVAALPCAILTFVNTPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSAGEAYLVYTDRLYSRSDFNNYLAALYKVVGTFLFGAAVSQSLTDLAKYMTGRLRPNFLAVCDPDWSRVNCSAYVQVEVCRGSSANVTESRLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYTRVSDHKHHWSDVLVGLLQGALVASLTVRYISDFFKARPPQHCPEEEDLERKPSLSLTLALGETDCNHYGYPVSSS
What is the function of this protein?
Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P.  Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly.  Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound.  Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes (By similarity).  Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity (By similarity).
What are the official names of this protein?
Phospholipid phosphatase 2, Lipid phosphate phosphohydrolase 2, PAP2-gamma, PAP2-G, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, PAP-2c, PAP2c.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.