PharMolix/UniProtQA huggingface dataset:
Protein: IF1_HELPJ
Sequence: MARDDVIEVDGKVIEALPNATFKVELDNKHVVLCRISGKMRMHYIRIALGDRVKLELTPYSLDKGRITFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_ROSDO
Sequence: MPTIQQLIRKPRQPKIKRSKSMHLQECPQKRGVCTRVYTTTPKKPNSAMRKVAKVRLTNGFEVISYIPGESHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GLMS_LISMO
Sequence: MCGIVGYIGTNNAKGILLEGLEKLEYRGYDSAGIALQNKELVTVVKEKGRIADLASLVPSDAFGTTGIGHTRWATHGKPNHENAHPHQSKSGRFTIVHNGVIENYTLLKEEYLKNHSFVSDTDTEVIVQLIELFAAELSTKEAFKKALSLLHGSYAICLIDQTNTETLYAAKNKSPLLIGKGENFNVIASDAMAVLKETDEFVEIMDKEIVIVTKDGFTLETLEGEEITRASYKAELDASDIEKGTYPHYMLKEIDEQPAVTRKIIQAYQDEAGEINVDKTIIDEILSSDRIHIVACGTSYHAGLVGKNLIEKMAKIPVEVHVSSEFAYNLPLMSKKPLFIFITQSGETADSRQCLVKVKELGYRTLTLTNVPGSTLDREADHSMYLYAGPEIAVASTKAYTAQISVLAVLAVSLGREIGDEEALNINLAAELGIVATAMEAMVSSKEVIEHIAGEYLATSRNAFFLGRNIDYFVAMEAALKLKEISYIQAEGFASGELKHGTIALIEDGTPVLALITQESINWNIRGNVNEVLARGAKTCIFAMENVAQPGDRFVIPQVHPLLTPLASVIPCQLLAYYAALHRDCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_AROAE
Sequence: MELAKSFEPAAIEARWYPEWESRGHFDAGLDKSNPNAFCILLPPPNVTGTLHMGHGFNQTIMDALTRYHRMRGFNTLWQPGTDHAGIATQIVVERQLDAKGVSRHDLGREKFVEKVWEWKEYSGGTITRQMRRLGTSPDWKRERFTMDEGLSKTVTETFVRLYNEGLIYRGKRLVNWDPKLGTAVSDLEVVSEEEDGFLWHITYPFSDGPVGDLKGLTVATTRPETMLGDVAVMVHPEDERYAHLIGKTVRLPLCERDIPIIGDDYVDREFGTGCVKVTPAHDFNDYAVGLRHNLPMISILRLDAHVSDDAPEKYRGMDRFVAREVIVQDLEAQGLLAGIKPHKLMVPRGDRTSAVIEPMLTDQWFVAMTKPGADGRSITAKALECVASGEIRFYPENWINTYNQWLNNIQDWCISRQLWWGHQIPAWYADVEGDSRVWVAHDEAEAKSLAAKDGFTGRLRRDDDVLDTWYSSALWPFSTLDWTAEWPEKSNDALDLYLPSSVLVTGFDIIFFWVARMVMMTKHITGKIPFRDVYVHGLIRDAEGQKMSKSKGNVLDPIDLIDGISADELAKKRTFGLMNPKQAQSIEKKTRKEFPEGIPAFGTDALRFTFASLATPGRDIKFDLSRCEGYRNFCNKLWNATRFVLMNCEGQDCGISAAAGSAACNTANLDFSFADRWIVSKLQRTEAEVAQHFRDYRFDLVSKAVYEFVWDEYCDWYVELAKVQIQSGTEAQQRATRRTLLRVLETVLRLAHPLIPFITEELWQTVAPLAGRKDTDSIMLARYPEADLSRLDEASEAKIAELKAIVGTCRNLRSEMNISPAQRMPLVAAGEATILTSYAPYLAGLARLSEVAVVDEIGTDELAPVAVAGRFKLMLRVEIDIAAERERIAKEIARLEGEMTKAESKLANESFVARAPATVVQQERERLASFVATLEKLRPQLEKLGAR
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y901_SACD2
Sequence: MWDIAKVKASIKPFVFALGRFFGNLYKEFVEKGCQKSAAALTYMSLFAMVPLMAVFYSMFSMFPAFDGVAQQLQDMIFSHFVPETGSEVQQYLANFSQQARNLSAAGAGLLVVTAYLMLTNIEKTFNAIWGVKAARRGITSFLLYWAVLTIGPLLLGAGLAMSTYLLSLKIIVNEYDAIGVTNLFFSYLPLFTTSAAFTLLFAAVPNCRVPIKFALIGGILTAVCFELLKIGFGWVVANSSFSQIYGAFAVVPLFLLWVNLLWMIILGGAVFVRTLAERGYAHSSSRYTDLMAVLQILAIFKEKSRTGESVTDGDCVRAGVGLVHWQQLRSKLTEKNWIAVTDSGFYVLCRDLSDVTVWDAACLVGATLAELEKTPRKRSRDGEWREEFSKRKDLLADDAKAHYGISLQALFSPQQVEELLEELPDEQSEKSK
What are the official names of this protein?
UPF0761 membrane protein Sde_0901.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRVN_THEPV
Sequence: ADPGPLQDFCLADLNSPLFINGYPCRNPALAISDDF
What is the function of this protein?
Cysteine protease able to degrade azocasein and benzoyl-arginine-beta-naphtylamide (BANA) in vitro.
What are the official names of this protein?
Peruvianin-1, Peruvianin-I.
What is the protein family that this protein belongs to?
Belongs to the germin family.
Protein: LOLD_VIBVY
Sequence: MNKLLQCHQVSKIYREGEFETEVLKGVDFELEQGELVAIVGTSGSGKSTLLHILGALDDATHGEVAFLDYQLSALSGNKQAQVRNQHLGFIYQFHHLLADFTAVENVAMPLLIGGKSPKQAKLAAEALLEKVGLQHRMHHRPSELSGGERQRVAIARALVNKPALVLADEPTGNLDHKTALQIYDLMRELNRESGTAFLVVTHDNELAAKMDRILYMQDGVLASDNR
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ABL_DROME
Sequence: MGAQQGKDRGAHSGGGGSGAPVSCIGLSSSPVASVSPHCISSSSGVSSAPLGGGSTLRGSRIKSSSSGVASGSGSGGGGGGSGSGLSQRSGGHKDARCNPTVGLNIFTEHNEALLQSRPLPHIPAGSTAASLLADAAELQQHQQDSGGLGLQGSSLGGGHSSTTSVFESAHRWTSKENLLAPGPEEDDPQLFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESSITEAVEKQLNANATSASSSAPSTSGVATGGGATTTTAASGCASSSSATASLSLTPQMVKKGLPGGQALTPNAHHNDPHQQQASTPMSETGSTSTKLSTFSSQGKGNVQMRRTTNKQGKQAPAPPKRTSLLSSSRDSTYREEDPANARCNFIDDLSTNGLARDINSLTQRYDSETDPAADPDTDATGDSLEQSLSQVIAAPVTNKMQHSLHSGGGGGGIGPRSSQQHSSFKRPTGTPVMGNRGLETRQSKRSQLHSQAPGPGPPSTQPHHGNNGVVTSAHPITVGALDVMNVKQVVNRYGTLPKGARIGAYLDSLEDSSEAAPALPATAPSLPPANGHATPPAARLNPKASPIPPQQMIRSNSSGGVTMQNNAAASLNKLQRHRTTTEGTMMTFSSFRAGGSSSSPKRSASGVASGVQPALANLEFPPPPLDLPPPPEEFEGGPPPPPPAPESAVQAIQQHLHAQLPNNGNISNGNGTNNNDSSHNDVSNIAPSVEEASSRFGVSLRKREPSTDSCSSLGSPPEDLKEKLITEIKAAGKDTAPASHLANGSGIAVVDPVSLLVTELAESMNLPKPPPQQQQKLTNGNSTGSGFKAQLKKVEPKKMSAPMPKAEPANTIIDFKAHLRRVDKEKEPATPAPAPATVAVANNANCNTTGTLNRKEDGSKKFSQAMQKTEIKIDVTNSNVEADAGAAGEGDLGKRRSTGSINSLKKLWEQQPPAPDYATSTILQQQPSVVNGGGTPNAQLSPKYGMKSGAINTVGTLPAKLGNKQPPAAPPPPPPNCTTSNSSTTSISTSSRDCTSRQQASSTIKTSHSTQLFTDDEEQSHTEGLGSGGQGSADMTQSLYEQKPQIQQKPAVPHKPTKLTIYATPIAKLTEPASSASSTQISRESILELVGLLEGSLKHPVNAIAGSQWLQLSDKLNILHNSCVIFAENGAMPPHSKFQFRELVTRVEAQSQHLRSAGSKNVQDNERLVAEVGQSLRQISNALNR
What is the function of this protein?
Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis; critical for embryonic epithelial morphogenesis regulating cell shape changes and cell migration.  Plays a critical role in transducing embryonic midline repulsive cues; may regulate cytoskeletal dynamics underlying a growth cone's response to midline cues.  The ability of pCC/MP2 axons to correctly interpret midline repulsive cues and stay on the ipsilateral side is dependent on the strength of both Slit/robo and Abl-dependent signaling pathways.
What are the official names of this protein?
Tyrosine-protein kinase Abl, D-ash, Protein abelson.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_CALS4
Sequence: MMKLARHAKILEIISEKEIETQEELAAELQKRGIDVTQATVSRDIKELRLIKVLTEDGKRYKYAPMTKVDTNISERLMTLLSESIVNVDYAGNIIVIKTLSGSASAAAEAIDTLNWKNIVGTIAGDNTIFVLVRNQEDIQELVEKFRKLMK
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YT47_CAEEL
Sequence: MNLSTAIISCLCIGVLSYENKFQFTGTVYCKSNAPWCVRIRVIEVDTLVDDGVASVDFCSNEVTQTYDIGGVQENDGLLDRNFELQMVVFHNCSRNTETVFKTGIWRIPLPKAPTVHAPIRQHLNLNTNNSQ
What are the official names of this protein?
Uncharacterized protein B0416.7.
Protein: RS3_TREPA
Sequence: MGQKVSPIGLRLGINKVWSSRWYAGPREYAALLHEDLRIRSMIRSFPECKNADIAEVEIVRHPQRVTVVMHTARPGVVIGAKGVNIEKIGAEVQKRLNKKVQIKVKEIKRMELNAYLVAQNVARQLTARVSFRKCLRQACAGTMKSGAQGVKIRVSGRLGGAEMSRTEEIKEGRTPLHTLRADIDYGFAEAHTTYGSIGVKVWLYSGMMYGNECRKDVGSLLRRSRRESGQKSDELVRDERTHAERG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NMT_DEBHA
Sequence: MSEEDKKDPPKSIEDLMKLLSMGESLTEPQQKQMKDYKFWKTQPVPSFDEKIDSEGPIDQTKTPDDIPDTPLPLLNEFEWSTVDLEKTDQLDEVYKLLYENYVEDQDATFRFKYSHEFFNWALKPPGWRTEWHAGVRVKETGKLVAFIAAIPITLKLNKSQKVIPSVEINFLCVHKKLRSKRLAPVMIKEITRRVNKYDIWQALYTGGVVLPSPVATCRYTHRPINWSKLYDVGFSHLPANQTKSGMLANYALPNTTKTQGLRSMKIEDLDQVYDLLHKFQEKFDIVQVFEKDELAHWLLGGKSTDTSSNVIKSYVVENSEGSLTDFFSYYLLPFTVLDNPSHDELGIAYLYYYASDTAFKNDDESAYKQRLSSLMSDALVTSKKYNVDVFNCLSSQDNPYFIKNCKFGSGDGFLNYYLFNYKTWPITGGIDPQTKELVEDKSSGVGVILL
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKS1_ARATH
Sequence: MGQIQYSEKYFDDTFEYRHVVLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAVHRPEPHIMLFRRPLNYQQQQENQAQNMLVK
What is the function of this protein?
Associates with cyclin-dependent kinases (CDKs) and plays an essential role in the regulation of the cell cycle that affects plant growth rate.  May inhibit both the G1/S and G2/M phases.
What are the official names of this protein?
Cyclin-dependent kinases regulatory subunit 1, CKS1-At.
What is the protein family that this protein belongs to?
Belongs to the CKS family.
Protein: BTUC_VIBPA
Sequence: MDFQQLILNKERRWQRNLVIMSVVLVLLSTIHLMVGEVFLSPFQSLSVFEQKLLLDLRLPRLVAAAMIGAALAVSGATLQVLLGNVLAEPGVLGISGGASLAMVLVMFALPVLPTPMIFMLAAIAGSMLFTLILVGIARAMHLTTARLLLVGVALGILSSAIVTWAFYFSDDLSLRQLMYWLMGSIGGASWYQHTVTLVMLPVLVWLCCQGKPLDKLMLGEIHATQLGVDVHQMRWKLILAISVLVGCSVALGGIISFVGLVVPHLLRLAFGTENRYLLPLSAIFGAALLVFADIGARLLLDSAELPLGVMTTSIGAPIFIWMLVKSHDAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URE1_HELHE
Sequence: MKKISRKEYVSMYGPTTGDKVRLGDTDLILEVEHDCTTYGEEIKFGGGKTIRDGMGQTNSPSSHELDLVITNALIVDYTGIYKADIGIKNGKIHGIGKAGNKDLQDGVCNRLCVGPATEALAAEGLIVTAGGIDTHIHFISPQQIPTAFASGITTMIGGGTGPADGTNATTITPGRWNLKEMLRASEEYAMNLGYLGKGNVSFEPALIDQLEAGAIGFKIHEDWGSTPSAINHALNIADKYDVQVAIHTDTLNEAGCVEDTLEAIAGRTIHTFHTEGAGGGHAPDVIKMAGEFNILPASTNPTIPFTKNTEAEHMDMLMCHHLDKNIKEDVEFADSRIRPQTIAAEDKLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLPEEKGDNDNFRIKRYISKYTINPAITHGISEYVGSVEVGKYADLVLWSPAFFGIKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFGHHGKAKFDTNITFVSQVAYENGIKHELGLQRVVLPVKNCRNITKKDLKFNDVTAHIEVNPETYKVKVDGNEVTSHAADKLSLAQLYNLF
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_SYNE7
Sequence: MSRRTSAQKRSVNPDPKFNSRLASMMVARLMDSGKKSLAFRILYSAFDLIQERTGNDPLELFEQAVRNATPLVEVRARRVGGATYQVPMEVRSERGTAMALRWLVQYSRQRPGKSMAIKLANELMDAANETGSSVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GATA_CHLTE
Sequence: MQFHGYEDLRSRLLSGELTCEQVISDYLQRIDSSRDDNIFTVVFHDEAMARARELDSKLQRGEAPGVLFGMPIAIKDNIAMKGAPLSCASKILAGYESVYDATVIKRMQAEDAIFVGRTNMDEFAMGSSNENSAIGPVPNPYDKTRVPGGSSGGSAAAVANDLAMVALGSDTGGSVRQPAGFCNIIGLKPTYGRISRYGLVAFASSFDQIGLLAANCDDAALVLGVIAGKDEHDATSSHHDVPEYDTAMDHVSVDGLRIGVPRAFFPESLNADVAGVVKAGLKKLEEAGAELVEIDLPESDYAIAAYYILVTAEASSNLARFDGARYGYRSPDSPDLSSMYVNSRTEGFGAEVKRRIMLGTYVLSAGYYDTYYKKAQQVRRVFQDKYREAFEKVDVIFGPTSPFPPFGIGDKMDNPLEMYLADVFTVPASIVGMPAISVPVGFDSLGLPVGAHLICNFFEEGKMLGIARHLQTLCQTAPSN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: FADI_SHESH
Sequence: MSDRQQVTNARGDRIAIVTGLRTPFAKQATAFHGVSALDMGKMVVNEMLSRSELDPKQIEQLVYGQVVLMPAAPNIAREIVLGTGMDVATDAYSVTRACATSFQSTVNVAESIMTGNIEIGIAGGADSSSVVPIGVSKKLAHALIDLNKARSFGQKLAIIRRLGLKDLLPVPPAVAEFSTGLSMGQTAEQMAKTYNISRADQDALAHRSHSLATETWNAGHLTDEVMAAHVPPYKSFIDRDNNIRENSTIESYAKLRPAFDRKHGTVTAATSTPLTDGASAVLLMSESRAKALGYDPIGYIKSYAFSAIDVWEDMLMGPSYATPLALKRAGMELEDLTLIEMHEAFAAQTLANMQMFGSKKFAAEKLGRNRAIGEIDMSKFNVLGGSLAYGHPFAATGTRLITQVCRELKRRGGGTGLTTACAAGGLGAAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SALPB
Sequence: MIALIQRVTRASVTVEDEVTGEIGPGLLVLLGVEKEDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRAQALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFT1_YEAST
Sequence: MSNSRYSQTESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSVINQMTDSLGSMFTDIKNSSSRLTRSLKAGNSIWRMVGLALLIFFILYTLFKLF
What is the function of this protein?
Vesicle SNARE required for retrograde transport within the Golgi complex.
What are the official names of this protein?
Protein transport protein SFT1, P14.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: NDK_PROM4
Sequence: MVAERTFLAIKPDGVQRGLVGEILSRFERKGFKLIALKQLIPSRALAEQHYGVHRERPFFKGLVDFITSGPVIAMIWEGEGVILGARKLIGSTKPLDADPGTIRGDLAIDIGRNVIHGSDGPETASFEIGLWFESSELSDWNPSDQLWRVE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFA_SALA4
Sequence: MIKWPWKAQEITQNEDWPWDDALAIPLLVNLTAQEQARLIALAERFLQQKRLVALQGFELDSLKSARIALIFCLPILELGIEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHSQRVVQSGQSWQQGPIILNWLDILDSFDASGFNLIIHEVAHKLDMRNGDRASGIPFIPLRDVAGWEHDLHAAMNNIQDEIDLVGESAASIDAYAATDPAECFAVLSEYFFSAPELFAPRFPALWQRFCQFYRQDPSQRLRVSAAEGDYGEESEH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_NOCSJ
Sequence: MASIEAVGAREILDSRGNPTVEVEVLLDDNSFARAAVPSGASTGAFEAVELRDGGDRYLGKGVAKAVEGVIQTIAPAIEGLAADDQRLVDQTMLELDGTPNKGKLGANAILGVSLAVARAAADSAELPLYRYVGGPNAHLLPVPMMNILNGGSHADSNVDVQEFMIAPIGAPTFREALRSGAEVYHALKSVLKKKGLATGLGDEGGFAPNLDSNRAALDLIAEAVSAAGLTLGKDIALAMDVAASEFYKDGSYAFEGGTKTAEQMTAYYADLVASYPIVSIEDPLDEEDWAGWKALTDELGSKIQIVGDDLFVTNVERLQRGITGGQANALLVKVNQIGSLTETLDSVELAHRNGYRCMMSHRSGETEDTTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEDELGDAARYSGASAFPRYAG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KHSE_YERPY
Sequence: MVKIYAPASIGNVSVGFDVLGAAVSPIDGTLLGDCVSVTAAERFSLHNEGRFVSKLPDDPKQNIVYQCWERFCQEMGKEIPVAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCGQPLDKVTLLGMMGELEGRVSGSIHFDNVAPCYLGGMQLILEQEGYISQDVPGFSDWLWVMAYPGIKVSTAEARAILPAQYRRQDCITHGRNLAGFIHACHTQQPDLAAKMMKDVIAEPYRTQLLPGFAAARQAAQDIGALACGISGSGPTLFAVCNDQATAQRMAGWLQNHYLQNDEGFVHICRLDTAGARLLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_HELPH
Sequence: MGYIPYVIENTDRGERSYDIYSRLLKDRIVLLSGEINDSVASSIVAQLLFLEAEDPEKDIGLYINSPGGVITSGLSIYDTMNFIRPDVSTICIGQAASMGAFLLSCGAKGKRFSLPHSRIMIHQPLGGAQGQASDIEIISNEILRLKGLMNSILAQNSGQSLEQIAKDTDRDFYMSAKEAKEYGLIDKVLQKNVK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_BRUME
Sequence: MANDPIHQFQVSRWIPIDVGGVDLSFTNVSAFMVATVVLASGFLYLTSSGRGLIPTRLQSVSEMAYEFVATSLRDSAGSKGMKFFPFVFSLFMFVLVANFIGLFPYFYTVTSQIIVTFALSLLVIGTVIFYGFFKHGFGFLKLFVPSGVPGIIVPLVVLIEIISFLSRPISLSVRLFANMLAGHITLKVFAGFVVSLSSLGALGIGGAVLPLLMTVAITALEFLVAFLQAYVFTVLTCMYINDAVHPGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.