PharMolix/UniProtQA huggingface dataset:
Protein: JM703_ORYSJ
Sequence: MMGVTTTLNEDTEPSIPPGFGPFATLPLWGIHNDAKPAVTHSTPVQALQSIRKDSEECQPSAAVSRSDTPCSTSGTQTCRKSLRNRPPIDYSRFEHISDEDSDVEIVEKDVSSTRRRQQLPKGVLRGCAECSDCQKVIAKWNPAGARRPVLDEAPVFYPTEEEFEDTLKYIESIRPMAEPYGICRIVPPSSWKPPCLLKDKSIWEGSKFSTRVQKVDKLQNRKSSKKGRRGGMMKRRKLAESEENSATAHTQTGMQQSPERFGFEPGPEFTLQTFQKYADDFSKQYFRKDTSMDSVPSVEDIEGEYWRIVEVPTEEIEVIYGADLETGTFGSGFPKLSPETKSDAEDKYAQSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNLESAMRKHLPELFEEQPDLLHNLVTQFSPSLLKSEGVHVYRCVQHEGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPIGHNAVELYREQARKITISHDKLLLGAAREAIRAQWDILFLKRNTADNMRWKSICGADSTIFKALKARIETELVQRKTLGVPAQSRKMDAEFDSIDRECALCYYDLHLSASGCPCCPEKYACLVHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAIHRWGVSDLGLSLSSCVKREKVQDSKTVRRLTDGPRRSYMSQASAVSLVSSSTSNEQKDEGNKIMKIASPQTNNVCPSVEQRKSENISPLKEPCVRNELSCTTNSDSNGLQYNGGLGGHKGSAPGLPVSSSPSFSSNVATRPISTSSVSMKIVQGLVASKSCIQASSRTGDSRSLLGEHHNRSPAMIHDGTNMKSSLESSNNSCRLIASDYNATPCHSSKDQVLVTPGTNASVVTLKDSSQVHSASSQQFVRTGPWTQSASHEASSPSTSALKPSLDPPAMKNLYGGFTQGSAHPGPPSFSNQQPNDGRLQRTSESLPGVEARARGHPTVTAQPALEIHSRNGGAQKGPRIANVVHRFKCSVEPLEIGVVLSGRLWSSSQAIFPKGFRSRVKYFSIVDPIQMAYYISEILDAGMQGPLFMVKLENCPGEVFINLSPTKCWNMVRERLNMEIRRQLNMGKSNLPTLQPPGSVDGLEMFGLLSPPIVQAIWARDRDHICTEYWRSRPHVLIEDPNNRHMLSQGPPLLALRGLIQRANRDELQVLRSLMTNSNNLDDSSRQQAAHIIEEEIAKQLC
What is the function of this protein?
Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a specific activity for H3K4me3, H3K4me2 and H3K4me1.  No activity on H3K9me3/2/1, H3K27me3/2/1 and H3K36me3/2/1.  Involved in the control of stem elongation by regulating methylation states of H3K4me3 on cytokinin oxidase (CKX) gene family, which may cause increased expression of CKX genes and reduced cytokinin levels.  Prevents ectopic retrotransposition by regulating the levels of H3K4me3 in two non-LTR retrotransposons KARMA and LINE-1 (L1) and reinforcing their repressed states.
What are the official names of this protein?
Lysine-specific demethylase JMJ703, Jumonji domain-containing protein 703, Lysine-specific histone demethylase JMJ703, Protein JUMONJI 703, [histone H3]-trimethyl-L-lysine(4) demethylase JMJ703.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PA_PSEA8
Sequence: MSRVTLSRYLIEQTRSHNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNEILLEANEWAGNLAGMASEEMDHPYQIPGRYPKGAYLLVFDPLDGSSNIDVNVSVGTIFSVLRCPNEYLNQNDTLREEAFLQPGTTQVAAGYAIYGPQTMLMLTLGNGVKGFTLDRELGSFVLTHDNISVPESTAEFAINMSNQRHWEAPVKRYVEELLAGKEGPLGKNYNMRWIASMVADVHRILTRGGVFMYPRDAREPEKPGKLRLMYEANPMSFIIEQAGGAATNGTQRILDIKPENLHQRVAVFLGSKQEVERITGYHAE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLP3_PLAVT
Sequence: MGPWEAKWIRHSDVRPFPQPEPMTVEEKVAVMLKPELHVSSGCHPYPAVNDLGETNGGLKTTGAPSGMCKGSGWGSQVYGRHASFRGVWAIMYVWYFPKDMPSAHFGHRHDWEHVIVWIEKPVVENVKILAVTPSFHDGYSKQVPPDPSHLNGLAAKFIYESEWPINHALRPTRKGGKKQDLILWEQMSSNARHALNIVPWGAANTPFNDFVFMGRLEKAFPF
What is the function of this protein?
Probable secreted effector that may act as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system (PubMed:32117400).  Seems not to induce necrosis, neither in several susceptible or resistant Vitis species nor in the dicot model plant Nicotiana benthamiana (PubMed:32117400, PubMed:35152834).
What are the official names of this protein?
NLP effector protein 3, Nep1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
Protein: METN_ECO57
Sequence: MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROB_BACCR
Sequence: MKKQRVVVKIGSSSLADSHGGISTEQLSDHVAALARLKEDGHEVVLITSGAVAAGFSALGYPSRPVTIKGKQAAAAVGQSLLMQAYTEEFRKYGIVTAQLLLTRSDFSRKEQYSNAYATLGELLNRSALPIINENDSISLEELTFGDNDMLSALVSGLVSADMLMIFTDVNGLYDKNPQKNADAKKYYFLPEVTEEISSLAGDAGSKLGTGGMKSKIDAAKTALSLGVSVFIGTGRGQEKFVNVLKGKGDGTYVGNAPQKEMKMNKQWIALHSLVSGQIEVDAGAATAIIQHGKSLLPAGVTNVSRFFQVGEVVEVVTQQGRVIGKGQCTYSAEELIDVKGMQSQDIQVRGERHSYEVIHRDHWVSL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y089_RICCN
Sequence: MSLTQILLILFVGILVTTPHDIFIIIKELKKIKAYLINIKSSIVKNIDEPLETEQVNFYLKKIINLEGYYHGSYDLTTIKEKYYTLIINNDLIENESVPDITEKH
What are the official names of this protein?
Uncharacterized protein RC0089.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DEOC_STRE4
Sequence: MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVAYAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDYQAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGGATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANGGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_CAUVC
Sequence: MDRAQKQESIESLKSVFADAGAVVVTHYMGLTVAEMTDLRLRLRKEGAAIKVVKNTLALKALDGKLGDKGDKLFTGPVAIAYGPDAVSAAKIAVQFAKENDKLKIVGGVLDQTNVLDEAGVRALATLPSLDELRGKLIGLIQAPATKIAGVLQAPAAQLARVFNAYATKDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CBPZ_MOUSE
Sequence: MPTMPLLLAALAALAVLALAARPSPSCSPGPDPSGKCQRLVYTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVESSPEYMLLGVIHFLLEGQCNPDLRLLGCSVLAPRCEGGHTQRPCRHVCEGLREACQPAFDAIDMAWPYFLDCAQYFAPEEEGCYDPLEELRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREVLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKNPHEKKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQQNKEPLLNFLEMVHRGIKGMVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKKAGRVDFILHPLATGPKNFLPGPSRALPRFQDPQREPTQMDFEPPRARRQPASGSKPWWWAYFTSLSPYKPRWLLKY
What is the function of this protein?
Cleaves substrates with C-terminal arginine residues.  Probably modulates the Wnt signaling pathway, by cleaving some undefined protein.  May play a role in cleavage during prohormone processing (By similarity).
What are the official names of this protein?
Carboxypeptidase Z, CPZ.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CYB_THRAP
Sequence: MTNMRKSHPLIKIINHSFIDLPAPSNISAWWNFGSLLGVCLALQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYAHANGASMFFIFLYFHIGRGIYYGSYSFMETWNMGVILIITVMATAFMGYXLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGXFSVDKATLTRFFAFHFILPFIITALVAIHLLFLHETGSNNPSGLNSNSDKIPFHPYYTIKDILGLLLMLLTLLSLTLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLFPALHTSKQRSMTFRPLSQCLLWLLVANLIILTWIGGQPVEPPFISIGQLASISYFCIILILMPTTSLMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL7A_PICTO
Sequence: MESYVKFQTPETLEKAVLDMVENSYKTGKVRKGTNEVVKSIERGESKLVVIAEDVSPAEVVYYLPTLCEERKVPYVYVKKKSDLGLKVGIASAASVSIVDYGKNDDAYKSIVSQINDAKSGKSENKE
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_SYNPW
Sequence: MARAFPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTSWNDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVHGQIKDRLKANAAPIQLPIGAEGDLSGIIDLVENKAHIYKDDLGQNIEVTDVPDDMKDQVAEWRTYLMEAVAETDEALIEKFLETGELSVEELKAGIRKGVLKHGLVPVLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLPNGEEAVRPSDDKAPFSALAFKVMADPYGKLTFVRMYSGVLAKGSYVLNSTKDSKERISRLVVLKADDREEVDELRAGDLGAVLGLKATTTGDTLCSAEDPIVLETLFVPEPVISVAVEPKTKGDMEKLSKALVALAEEDPTFRVNTDQETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRASSRGEGKFSRQTGGKGQYGHVVIEMEPGEPESGFEFINKIVGGVVPKEYIKPSEMGMKETCESGVIAGYPLIDVKVTMIDGSYHDVDSSEMAFKIAGSMAFKDAVKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQAIDDGTSKVSAKVPLAEMFGYATELRSMTQGRGIFSMEFSHYEDVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAS_SALHS
Sequence: MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPD_LEGPL
Sequence: MNSLQALIEQAFENRQNLSLNTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLKKAVLLSFKLFPNQIIDAGFCKFYDKIPLKYTDSSNEQFQQSGVRVVPHAMVRRGAYIAKNTVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISGGAGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPSHDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSM4_YEAST
Sequence: MMDGSITRKVTSTLSNQLATWKWKLQLSLLERKLATINNDYFLLQWELLFITNEVMKWKEMIAFLESQLFCTTQNFVAQETHDRETFQSLVDDYNKQLSENNLIISVLKSRPQLSSFPIYLSDEVCSHLKFVIAELNSLIIVFFISLVFLWVSIEV
What is the function of this protein?
Involved in chromosome segregation during meiosis.  Involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements.
What are the official names of this protein?
Chromosome segregation in meiosis protein 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein: SET5_SCHPO
Sequence: MNPYETEIYKVVPIPNKGMGMIAKVKIPVGTRIFAETPLIRTKSDAKEIEEALSTKTKEEQEAFHRLFNAHPDTMGPFLGPFYSNALTIDETKGGMFLLGSRMNHDCSPNVKHTWNPRLDQVTVHAVRDIEAGEEILTTYIDLHKSHTERQKILLEHFGFKCYCSVCSVEERKIRKISDLRRKQLAYYDRTMAKMCIVNPRGALRALRHRIHIAHEELLFGRLDIIALLDAFRLCVIHGDFERASIFAKKGTKAISLYEGTDSEKYLKISKYVENPRSHALAEGVPALPLFLEEDDELSDLEDNLWGCKLEEDVYSDTD
What are the official names of this protein?
SET domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAS6_PSEAB
Sequence: MDHYLDIRLRPDPEFPPAQLMSVLFGKLHQALVAQGGDRIGVSFPDLDESRSRLGERLRIHASADDLRALLARPWLEGLRDHLQFGEPAVVPHPTPYRQVSRVQAKSNPERLRRRLMRRHDLSEEEARKRIPDTVARALDLPFVTLRSQSTGQHFRLFIRHGPLQVTAEEGGFTCYGLSKGGFVPWF
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Processes pre-crRNA into individual crRNA units.  Absolutely required for crRNA production or stability.  Upon expression in E. coli endonucleolytically processes pre-crRNA, although disruption and reconstitution experiments indicate that in situ other genes are also required for processing.  Yields 5'-hydroxy and 3'-phosphate groups.  The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.
What are the official names of this protein?
CRISPR-associated endonuclease Cas6/Csy4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas6 family. Cas6f/Csy4, subtype I-F/Ypest subfamily.
Protein: MIAA_STRP6
Sequence: MTKIKIVVIVGPTAVGKTALGISLAKALNGEIISGDSQQVYRQLDVGTAKATQEEQEAAVHHLIDIREVTESYSAYEFVQDAQKAISDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQEAVKAYRQELDQLSDQEVYELLQVKSITIKQLNRRRAIRALELSQFADDLENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEHYPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVNFTAITAPDYPQVVHDRVRDFLGQKEKS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CFXQ_PORPU
Sequence: MTQLTNIVSNDTLVNLQEEYDKTQIQEVLNELNQELIGLVPVKTRIREIAALLLIDRLRRKLELVSGNPGLHMSFTGSPGTGKTTVAMKMADILHRLGYIKKGHLLTVTRDDLVGQYIGHTAPKTKEVLKQAMGGVLFIDEAYYLYKADNERDYGSEAIEILLQVMENQRNDLVVIFAGYKDRMEKFYESNPGLSSRVANHVDFPDYTSEELLQIAKMMIEEQQYCFTEEADKTLLEYTERRMKQPYFANARSIRNAIDRARMRQANRIFASGEKVLTKADLVTIEAEDILKSRLFSLPNN
What is the function of this protein?
Necessary for the expression of RuBisCO.
What are the official names of this protein?
Protein CfxQ homolog.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LYRIC_MOUSE
Sequence: MAARSWQDELAQQAEEGSARLRELLSVGLGFLRTELGLDLGLEPKRYPGWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEAAPPTPAPDDLAQLKNLRSEEQKKKNRKKLPEKPKPNGRTVEVPEDEVVRNPRSITAKQAPETDKKNEKSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLDSTIPGIENIITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSRLNENLTVNGGGWSEKSVKLSSQLSEEKWNSVPPASAGKRKTEPSAWTQDTGDTNANGKDWGRNWSDRSIFSGIGSTAEPVSQSTTSDYQWDVSRNQPYIDDEWSGLNGLSSADPSSDWNAPAEEWGNWVDEDRASLLKSQEPISNDQKVSDDDKEKGEGALPTGKSKKKKKKKKKQGEDNSHTQDTEDLEKDTREELPVNTSKARPKQEKACSLKTMSTSDPAEVLIKNSQPVKTLPPAISAEPSITLSKGDSDNSSSQVPPMLQDTDKPKSNAKQNSVPPSQTKSETNWESPKQIKKKKKARRET
What is the function of this protein?
Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically.  Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor.  Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion.  Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium.  Induces chemoresistance (By similarity).
What are the official names of this protein?
Protein LYRIC, 3D3/LYRIC, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Cell junction, tight junction. Nucleus, nucleolus. Cytoplasm, perinuclear region. Note=In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain. TNF- alpha causes translocation from the cytoplasm to the nucleus (By similarity).
Protein: CYSG_SALPC
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNY
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: YDAS_BACSU
Sequence: MLSFLVSLVVAIVIGLIGSAIVGNRLPGGIFGSMIAGLIGAWIGHGLLGTWGPSLAGFAIFPAIIGAAIFVFLLGLIFRGLRKEA
What are the official names of this protein?
UPF0410 protein YdaS.
What is the protein family that this protein belongs to?
Belongs to the UPF0410 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRTE_PANAN
Sequence: MTVCAKKHVHLTRDAAEQLLADIDRRLDQLLPVEGERDVVGAAMREGALAPGKRIRPMLLLLTARDLGCAVSHDGLLDLACAVEMVHAASLILDDMPCMDDAKLRRGRPTIHSHYGEHVAILAAVALLSKAFGVIADADGLTPLAKNRAVSELSNAIGMQGLVQGQFKDLSEGDKPRSAEAILMTNHFKTSTLFCASMQMASIVANASSEARDCLHRFSLDLGQAFQLLDDLTDGMTDTGKDSNQDAGKSTLVNLLGPRAVEERLRQHLQLASEHLSAACQHGHATQHFIQAWFDKKLAAVS
What is the function of this protein?
Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes.
What are the official names of this protein?
Geranylgeranyl diphosphate synthase, GGPP synthase, Farnesyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: PBPA_NEIFL
Sequence: MIKKIITTCMGLNNGLALFGVGLIAIAILVTYPKLPSLDSLQHYKPKLPLTIYSSDGQVIGVYGEQRREFTKIDDFPKILKDAVIAAEDKRFYDHWGVDVWGVARAVIGNVMAGGVQSGASTITQQVAKNFYLSSERSFTRKFNEALLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQTYFNKNVNDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQAYILNNMLEEGMITLQQRDQALKEELHYERFVQNIDQSALYVAEMARQELFEKYGEDAYTQGFKVYTTVDTAHQRVATEALRKVLRNFDRGSSYRGAENYIDLSKSDNVEETVSQYLSTLYTVDKMIPAVVLEASRKGVQIQLPSGRKVTLNNHALGFAARAVNNEKMGDDRIRRGSVIRVKGSGDTFTVVQEPLLQGALVSLDAKTGAVRALVGGYDYHSKTFNRATQAMRQPGSTFKPFIYSAALAKGMTASTMINDAPISLPGKGANGKAWNPKNSDGRYAGYITLRQALTASKNMVSIRILMSIGIGYAQQYIQRFGFKPSEIPASLSMALGAGETTPLRIAEGYSVFANGGYKVSAHVIDKIYDSQGRLRAQMQPLVAGENAPQAIDPRNAYIMYKIMQDVVRVGTARGAATLGRSDIAGKTGTTNDNKDAWFVGFNPNVVTAVYIGFDKPRSMGRAGYGGTIAVPVWVEYIGFALKGTSVKPMKAPEGVVTNGGEVYMRERMTTSSDLALDNSGIRPRPTQPARRAVPNENRRRAESNTAPAREESDETPVLPSNTGNNNRQQLDSLF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: ACCD_RHOPB
Sequence: MNWLTNVVRPKIRNILRRETPENLWIKCPDSGHLVFYKDVEANQFVIPGSNYHMRMGAAARLKSIFDNETWYDIALPEVTPDPLKFRDERKYVDRIKDARAKTGMNDAIKVGYGKLEGGAVVVAVQDFDFMGGSLGMAAGEAIVRGIELAVEKQSPFILFAASGGARMQEGILSLMQMPRTTVGVQMLRDAKLPYIVVLTNPTTGGVTASYAMLGDVQIAEPGALIGFAGARVIEQTIREKLPEGFQRAEYLKEHGMIDMVVHRHDLKATLARLCRLLTKAPMPEVIVESEPEPEPEPVVAEIIPPTSDLPVSAPAPAPVAAQTPAPAAPSA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.