PharMolix/UniProtQA huggingface dataset:
Protein: FER_RICFE
Sequence: MTYVVNDECVKCKYTDCVDVCPVDCFYEGEFMLVINPDECIDCGVCVPDCPIDAIKPESPELIEWVERAKDFIENKGWKNITKKKPALPDADKFKDEKNKFNKYINNMN
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: TBX6_XENTR
Sequence: MYHSELFQQYGTSYGMRPPHALAPTYPTAGGHHEAYRYPELDVPGQRFDGLFPALDPSQRILGAPPLTPLSLPPGPALGFGQLQPPCETPQLPGNVKMNLENKELWKQFHSIGTEMIITKSGRRMFPQCKVSVTGLEPDGKYLLLADIVPIDNSRYKWQEDRWEPSGRAEPRLPERVYIHPDSPAPGSHWMKQPISFHKIKLTNNTLDQMGHIILHSMHKYQPRFHIVRAQDVFSRRWGGCSSFTFPETLFLTVTAYQNEKITQLKIQTNPFAKGFREDGMKSKRDRSTRVKRKVIEPEEEEEEFQPEGECKRPLYTGPCDSTLSEELDIGRGLGIPLPSPDCSFHPITPPSRTPPSTQTPNPSLTANQEQGAALEMSSQTPETFLQAAGQSYPEQPPVRGGSLYPCPTDGHGAQNQRHPLSVQRLPQAFQGLQESLGNSPGEYKIYGGDVGCGGDFAPPSCAVAPSVRPSEERLPRGYSMNSELRFPHFLPNGGSKIGLQFSGAQLQRLYNGGGWM
What is the function of this protein?
Transcriptional activator.  Plays a role in ventral mesoderm specification and acts together with nog during muscle differentiation.  Mediates posterior pattern formation of the embryo, including specification of posterior mesoderm, via activation of the Wnt and Fgf signaling pathways (By similarity).
What are the official names of this protein?
T-box transcription factor TBX6, T-box protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: THUM3_BOVIN
Sequence: MSDVQEATNQLLDVNLCENQMSIQVTESGPRSESEHLQVTIGATVPTGFEQTAADEVREKLGSSCKISKDRGKIYFDITVDSLAQVHCLRSVDNLFVVVQEFKDYQFKETKEEVLKDFEELAGKLPWSDPLKIWKINTCFKKKKTKRRKLNPNSSKQKIDNGRGDTTVEKDVKKELTNSVSDSQISDYYENPAIKEQVSTLIGDGLTSCKDETEENSKEEADPEVLKFRVTCNRAGEKHCFSSNEAARDFGGAVQDYFKWKADMTNFDVEVLLNIHDNEVVVGIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCAPQPTDIIVDPMCGTGAIPIEGATEWSNCYHIAGDNNPLAVNRAANNISSLLTKIQVKEGKLPLGLPIDTIQWDICNLPLRTGSVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPGTGRAVLLTQDKKCFAKALSGMGHLWRKVHTVWVNIGGLHAAVYLLKRTPQSFVHPSEEDGERCPCTQR
What is the function of this protein?
Methyltransferase which catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates containing the characteristic 3'-CCA terminus of mature tRNAs (By similarity).  Also catalyzes the formation of N(2)-methylguanosine at position 7 of tRNA(Trp) (By similarity).  Requires the methyltransferase adapter protein TRM112 for tRNA methyltransferase activity (By similarity).
What are the official names of this protein?
tRNA (guanine(6)-N2)-methyltransferase THUMP3, THUMP domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_BACMK
Sequence: MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQMASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSAAVHPESRAVLETYAKGQNLEVVEIDHKNGVTDLEVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADVVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEINDVLIQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: AROA_DEHMC
Sequence: MKIHLDKSLPGGNIAVPSSKSYTIRGLIAAAQANGQSHIISPLIADDTLATRQVLSELGIDISTDAGSESWEITGNTFKAPSGNLFCRESAATLRFMSAVCARLPFECHLLAGHSLMRRPMLPLIQALHQLGIEIETRGNTTVINGQVITRSKVSLPGNISSQYVSALMLMAPACTHGLEIHLATPPASLPYLKMTKQTLGSFGIKVHSSIDWQEISIPPQPYLPARYRVEGDWSSASSFLALGAIAAPVFISNLDTDSFQADRIMIKFLAEMGAEIESGQNWVKVNPKPLSGINADLTHSIDLLPALAVAAACAKGQSILSGVRQARIKESNRIRAVSQGLSAMGINIIEEDDRLIIEGGQPKGAEIDSFGDHRIAMAFGILGSVVGETHISDAECVTKTYPDFWKNLESLGGKVTQDV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2340_CALS4
Sequence: MITKEMIDRINFLYHKSKSEGLTEEEKEEQRRLREAYVKEIKERVKRELDNLFADASHHHHHCHHHEH
What are the official names of this protein?
UPF0291 protein TTE2340.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_MYCCT
Sequence: MLINDTVVAPATNISTQAIALIRVSGSEAFLIVNKLIKDKKLEEKRGLFLRKLYFEDELIDEVVLSCFVAPNSFTGENVVEIACHGGILNTNKIINILIQSGARMALRGEFSQRSFLNGKIDLIQAEGINNLIHAKNDLALKIGVANMSGSNNKAIIELKDNLLDIISRIQVSIDYPDYDDVEGSSIEDLTNLLEIINDQINKLLMRSKMAFKNSEGIKTAIVGQTNVGKSSILNALINEDKAIVTDIPGTTRDIVEGQINLENVSLNLIDTAGIRKTSDVVENLGILKSKNLINEADLVLFVVNKENINDLDNQEIFELLKDKTYILIVNKAEKLSQTEKQNLEKKYENIVFTSAINHDIDQLVLRINQMYLNEEISKSDELILIGLNQITLVEQIKNKLSTALSVIKSGMPIDIVNVDLYDAWNLLNELIGVEYEDEIIDNIFRKYCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_BACSU
Sequence: MLTKCEGIVLRTNDYGETNKIVTLLTREHGKIGVMARGAKKPNSRLSAVSQPFLYGSFLMQKTSGLGTLQQGEMILSMRGIREDLFLTAYAAYVAELVDRGTEEKKPNPYLFEFILESLKQLNEGTDPDVITFIVQMKMLGVMGLYPELNHCVHCKSQDGTFHFSVRDNGFICHRCFEKDPYRIPIKPQTARLLRLFYYFDLSRLGNVSLKEETKAELKQVIDLYYEEYSGLYLKSKRFLDQMESMKHLMGENKS
What is the function of this protein?
Plays a role in DNA double-stranded break repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecR.  Is recruited to repair centers, foci that are the site of double-strand break(s) after RecN and before RecF; may actively recruit RecF.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Cytoplasmically located in untreated cells. Recruited to foci following treatment with DNA damaging agents; these foci are presumably the breaks themselves. They are almost always located within nucleoids.
Protein: TETO_CAMCO
Sequence: MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTDTINLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAKDGIQAQTRILFHALQIMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQHPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYHGSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLHLRDVIRISEKEKIKITEMCVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEILLPQRKFIENPLPMLQTTIAVKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLGNVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIEPLLLGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYSPVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIVSTQIKNDEVILKGEIPARCIQEYRNDLTNFTNGQGVCLTELKGYQPAIGKFICQPRRPNSRIDKVRHMFHKLA
What is the function of this protein?
Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
What are the official names of this protein?
Tetracycline resistance protein TetO, Tet(O).
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TetM/TetO subfamily.
Protein: RSMG_ANAD2
Sequence: MDSAFHEALASGIEALGLPVDEAARALLERYADRLLAWNRKVNLTAITAPAELAEKHLVDSLVLLPFLTGAGTLLDVGSGAGLPGIPLACARRDLSVTCCDGVAKKIAFVKAVSAELDLPVRGVAVRAEGEPEREGLPRADAVVSRALAEPDRWVPVGARYLAEGGTLFAMLGREVDRAGLEAAGAAEGLTLVGLDVYELPVSHAARAVARWQQR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DARG_ECO27
Sequence: MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPENMKVYALACKQKQVITGKMFITETGELMGPRWIVNFPTKQHWRADSRMEWIEDGLQDLRRFLIEENVQSIAIPPLGAGNGGLNWPDVRAQIESALGDLQDVDILIYQPTEKYQNVAKSTGVKKLTPARAAIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQDDILKLRFEAHYYGPYAPNLNHLLNALDGTYLKAEKRIPDSQPLDVIWFNDQKKEHVNAYLNNEAREWLPALEQVSQLIDGFESPFGLELLATVDWLLSRGECQPTLDSVKEGLHQWPAGERWASRKLRLFDNNNLQFAINRVMEFHC
What is the function of this protein?
Antitoxin component of a hybrid type II/IV toxin-antitoxin (TA) system.  De-ADP-ribosylates DNA modified by its cognate toxin DarT, which neutralizes the activity of cognate toxin DarT.  Neutralizes DarT in vivo in 2 ways, by reversing the ADP-ribosylation via the DarG macro domain and by interacting with (and presumably sequestering) DarT via the DarG C-terminal domain (PubMed:32023456).  In vivo the macrodomain alone neutralizes DarT toxin from non-cognate T. aquaticus.  The same domain de-ADP-ribosylates gDNA (PubMed:34408320).
What are the official names of this protein?
DNA ADP-ribosyl glycohydrolase, DarG, Antitoxin DarG.
What is the protein family that this protein belongs to?
Belongs to the DarG ADP-ribosyl glycohydrolase family.
Protein: YSNF_BACSU
Sequence: MKSIVGVYETPQETIAAIEGLLTKGYDSDDISVVTSRRDTDYLESRTGTEVNQAIDAHQDESESFFDKLKDYFTMDDTATHSKALSDLDIKTDEIDKYQEDLDDGKLLVAVDTDADVIAPIDNGNALSGGFSSTNELDYTTKEEKTMPLREEQLKVDKEDVQTGEVEIGKEVKTEKRDMDIPVRHDEIYVERRPVDENKTDAAPVNDSEEIRVPIVEEKLEVTKKPVVTDEVVVGKRTVEENEHISETVKKEEPRLNKEGKVDGLDDDPLNNK
What are the official names of this protein?
Stress response protein YsnF.
Protein: TAZM_ASPTN
Sequence: MGSIINIPGLPDGEFSNYEQVYLKMSRAFSHLQKEHWGIHCVCSVSRDSPNGSTFSETLRQAWMRLVVEYPGLSMVPVGLQKKYPRLDEKVVLLIQHWRVDALGTCMLLDRLFEILGQSTVPSTQPDQVQPNQPTPSFESAAGASKTEDADLQAYARDYIDSFHQRAVNADGLPYRGDATTPPSTTAHWDLDFSVDSTNAIKDACRHHKISVTAAIHTALARTVFSYLTETECQAGYTTVMAVNMRPYLPPPYNSKKHACQTFVASITPTVPYHSGFVESARSLTHEYRSWWSADFMRSLWWIYEYHLAKLSAPRPANAAPMKPPSGVTLSSLGVVDRNLRGGYGPNLRVDKFRFGVSMMTRQTILYAWTFKDRLTLSLNYNDAYYSDLMAREVMSRVASHLEKGLEVELNTV
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities (PubMed:35398258).  The first step of the pathway begins with the non-reducing polyketide synthase tazA that assembles one acetyl-CoA starter unit, five malonyl-CoA units, and catalyzes a series of Claisen condensations, methylation, PT-mediated cyclization, and finally releases the first hexaketide precursor through the R-domain.  The tazA product then undergoes reduction on its terminal ketone and the following pyran-ring formation by yet undetermined enzyme(s).  Dehydration and enoyl reduction, possibly involving the trans-enoyl reductase tazE leads to the next intermediate.  TazD is predicted as an acetyltransferase and might catalyze the acetylation steps leading to the synthesis of azaterrilone A.  Azaterrilone A is not the final product of the taz pathway and both the highly reducing polyketide synthase tazB and the dual enzyme tazHJ catalyze late steps of the pathway, leading to the production of the 2 final stereoisomers that contain additional polyketide modification whose structures have still to be determined (Probable).
What are the official names of this protein?
Azaphilone biosynthesis cluster protein M.
Protein: G6PI_STRPI
Sequence: MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2_CARAE
Sequence: XIGAGATSKLVY
What are the official names of this protein?
Phospholipase A2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
Protein: TEKT1_RAT
Sequence: MAKLLQSPPKFLPAEWYIANKSQYHRAEAQRSRSERLVAESQRLVEEIEKTTRKSQSDVNKKLEQRLEEVKFWKKELDDKLEHLVNETEDLLTYKIRLERSLESYKEPLHITEKCLAYREKRVGIDLVHDVVDQELQKEADIIHGVMNLLTRTVEEATEQIRLNRSAKYNLEKDLKDKFTAITIDDICFSLNNNSPDIKYSENVVRIEPNSVSLEDWLDFSNTNMQKADKQLNNSMALKTLVDQILSQTANDLRRQCEVVDTAFVNGLKETKDARNKLADHLAKVMDEIASQEKNIEVLENAITQQEGPAKVAHTRLENRTYRPNVELCRDVAQYRLIREVQEIKHNVARLEETLAQAQIQLKALFRRQLALQEEIQVKENTIYIDQVLCMEMRKSIPPRDGDDHGAWEGGIRAEAIC
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
What are the official names of this protein?
Tektin-1.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: MUTS2_OCEIH
Sequence: MNERVLRVLDFKSVTEMLKGQAETALGKERAKITKPLSSLDKINMLQDETDEAAKIIRLNQAIPLGGITDIRASVKRSSIGGILSTDECLDVANTLYGSRNVKNTIENMEELDIPILKELVEHITPIRELEQAIKSCIDDHGHIMDGASSQLRSIRSSIRTLESRIREKLENYTRSNSKMLSDAIITIRNDRYVLPVKQEYRGAIGGIVHDQSASGQTLFMEPKAVVDINNSLHESKSKEQLEIERILKDLSNQVASYEQDLLENVKVLTNIDFIYARGKLAQAMKASRPKMNDEGYMKMQQARHPMIPIDEVVANDIEFGREYTSIVITGPNTGGKTVTLKLVGLCTLMAQSGLQVPALDGCEMPVFDEVFADIGDEQSIEQNLSTFSSHMTNIVDIMKKITDRSLVLFDELGSGTDPQEGAALAMAILDEVISKQARVIATTHYPELKAYGYNREQVVNASVEFNVETLKPTYRLLIGVPGRSNAFDISTRLGLERATIERAKSLIGVDSKSVENMIASLEKSHLEAEQDYEQAHDVLLESEKLRNALEHEWNLFEQKKEKLYKKAEEKAEKAIQKAREEAETIVSEMRQMKDSAGLKEHEWIEARKMLDEAKPNLTKNGNQKQVDPKPVEDRQLQPGDEIKLLTVNQMGEVLERVSDKEYLVQVGIMKVKVKRKDLELIRKPKKKQVDPVTTIKGSNYHVSTELDLRGERYEDAILRLEKYVDDVLLAGYPKASIIHGKGTGALRKGVQEFVGRHPRIKGARPGESGEGGSGVTVIQLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: CM3C_CONSR
Sequence: RGCCNGRGGCSSRWCRDHARCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This toxin potently inhibits hNav1. 4/SCN4A (IC(50)=15. 11 nM).  It also displays lower activities on other human subtypes (Nav1. 1/SCN1A; IC(50)=132 nM, Nav1. 2/SCN2A; IC(50)=363. 8, Nav1. 3/SCN3A; IC(50)=89. 4, Nav1. 6/SCN3A; IC(50)=124. 9, Nav1. 7/SCN7A; IC(50)=152. 2).  At Nav1. 7/SCN9A, it does not elicit change in channel voltage-dependence of fast inactivation or activation, suggesting it acts as a pore blocker.  Interestingly, it blocks current inhibition in an irreversible manner (tested during 35 minutes).
What are the official names of this protein?
Mu-conotoxin SxIIIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EUMEF_EUMFR
Sequence: LNLKGLFKKVASLLT
What is the function of this protein?
Linear cationic alpha-helical peptide that acts as antimicrobial peptide by forming pore in membrane.  Has antibacterial activities against both Gram-positive and Gram-negative strains.  Has more potent activities against the yeast C. albicans.  Shows moderate mast cell degranulation and leishmanicidal activities.  Has a very low hemolytic activity.
What are the official names of this protein?
Eumenitin-F.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Eumenitin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Assumes an amphipathic alpha-helical conformation in a lipid environment. Forms a membrane channel in the prey (By similarity).
Protein: SSB_CHLMU
Sequence: MLFGYLVGFLAADPEERMTSGGKRVVVLRLGVKSRVGSKDETVWCRCNIWNNRYDKMIPYLKKGSSVIVAGELSVESYMGRDGSPQASISVSVDTLKFNSGSSRPESRGSDEGRQRSNDNVSLGFEGESLDTEIALDKEVYAGFGEDQQYASEDVPF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: ODO1_AZOVI
Sequence: MQDSVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLPAEAGTSTDVPHAPVRDQFVLLAKNQRRAQPVATSSVSTEHEKKQVEVLRLIQAYRTRGHQASQLDPLGLWQRTAPSDLSITHYGLTNADLDTPFRTGELYIGKEEATLREILQALQETYCRTIGAEFTHIVDSEQRNWFAQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPGTKRFGLEGGESLVPVVDEIIQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFEGKHLVELGSGDVKYHQGFSSNVMTSGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRVDATGEKVVPISIHGDSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVDTRSTEYCTDPAKMIQAPVLHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMYQKIAKQPTTRELYADALVKEGSLSQEEVQAKVDEYRTALDNGQHVLKSLVKEPNTELFVDWTPYLGHAWTARHDTSFELKTLQELNAKLLQIPEGFVVQRQVAKILEDRGRMGVGAMPINWGCAETLAYATLLKEGHPVRITGQDVGRGTFSHRHAALHNQKDASRYIPLQNLYEGQPKFELYDSFLSEEAVLAFEYGYATTTPNALVIWEASSGDFANGAQVVIDQFISSGETKWGALCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNIQVCVPTTPAQVYHMLRRQVIRPLRKPLVALTPKSLLRHKSAISTLEDLALGSFHPVLPEVDSLDPKKVERLVLCSGKVYYDLLDKRHAEGREDIAIVRIEQLYPFPEEELAEVMAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRVASAHKKELFLQYAGREASAAPACGYASMHAEQQEKLLQDAFTV
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RS16_STAAR
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DNAA_STACT
Sequence: MSKEEIWDKVLELAKNELTPISYSTWFEPPKTELIDIQENTAIILVESNFVQDFLKKQYTDIIADLIEKAIGTKLMPNFVIQEDLTEDKQVKDSAKAKSEAKPDVQAPQNSSEDQFNVHNTFETFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVLENNRDAKVIYTSSEKFTNEFIKSIRDNETEQFREKYRNIDVLLIDDIQFIQNKEQTQEEFFHTFNDLHQTGKQIVISSDRPPKEIAKLEDRLRSRFEWGLIVDITPPDYETRMAILQKKLEEEDVDIPLESLTYIANQIQSNIRELEGALTRVIAYSRLQNEAITTELTAEALKDIIQTPKSKKITIQDIQKVVGQYYNVRLEDFAAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHMKIQTDMSEDPIFKQEVENLEKEIRNQ
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_PSEA6
Sequence: MANYFNTLSLRQQLDQIGRCRFMQRSEFSEGCDFLKGKKIVIVGCGAQGLNQGLNMRDSGLDVAYALRQAAIDEKRDSFQRASGNGFTVGTYKELIPSADLVYNLTPDKQHSSVVEAIMPLMKEGASLGYSHGFNIVEEGQQIRSDITVVMCAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQQQGWDIAKALASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMQQAAAVLGYEKMVADGIDPAYAGALIQFGLEAITEALKIGGVTNMMDRLSNPAKIKAFDLSEQLKDMLKPLFGKHQDDIISGEFSRTMMEDWANGDANLLKWREETGQTGFENAPEYNGKIDEQEFFDNGVFIVAMIKAGVELAFDVMVEAGILPESAYYESLHETPLISNTIARKRLYEMNVVISDTAEYGNYLFANAAIPLLADKLMPSIGTELIGKPFAAASNSVDNKTLVAVNKAIREHGVESVGDTLRGYMTDMKAIVEAV
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HEM3_CHLPB
Sequence: MKKKLIIGTRSSPLALWQADFTQAELSKHFPDLEIELKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLISGEIDLAVHSLKDVPTETPEGLMLSAFTEREDTRDVIISKNGESLKTLKQDAKIATSSLRRTSQLLSMRPDFQMGDIRGNLNTRFKKFDESDFDAMMLAYAGVHRLNFGDRISEILPHEVMLPAVGQGALGIETRVDDEATKEIVSVMNNVNTEFCTKAERALLRHLQGGCQIPIGSYASLKNGNLHLLAYVGSVDGKRTIRNEITKENCTLPEQAEQAGIELAEELLKQGANEILAEIRKTC
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: INGK_ECOLI
Sequence: MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESGERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR
What is the function of this protein?
Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively (PubMed:7721718, PubMed:7665468, PubMed:10879466).  Can also use deoxyguanosine and xanthosine, but not adenosine, uridine, cytidine or deoxythymidine (PubMed:7665468, PubMed:10879466).  Shows a strong preference for guanosine (PubMed:7665468, PubMed:10879466).  dATP can serve as a phosphate donor as well as ATP.  Shows weaker activity with UTP and CTP (PubMed:7665468, PubMed:10879466).
What are the official names of this protein?
Guanosine-inosine kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: CRIP2_HUMAN
Sequence: MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP
What are the official names of this protein?
Cysteine-rich protein 2, CRP-2, Protein ESP1.