PharMolix/UniProtQA huggingface dataset:
Protein: GNT2A_HUMAN
Sequence: MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF
What is the function of this protein?
Determines the expression of the blood group I antigen in erythrocytes.
What are the official names of this protein?
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
Protein: XTH11_ARATH
Sequence: MRGSDQKILLMVMVVVAVVAAAQGQEETTGFVTWGNNYYQTWGHQALVINKTSELQLTLDKNSGSGFESQLIYGSGYFNVRIKAPQTTSTGVITSFYLISRSSRHDELCFQILGKNGPPYLLNTNMYLYGEGGKDQRFRLWFDPTKDYHSYSFLWNPNQLVFYVDDTPIRVYSKNPDVYYPSVQTMFLMGSVQNGSIIDPKQMPYIAKFQASKIEGCKTEFMGIDKCTDPKFWWNRKQLSSKEKTLYLNARKTYLDYDYCSDRQRYPKVPQECGSYT
What is the function of this protein?
May catalyze xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 11, At-XTH11, XTH-11.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: FARP_SCHGR
Sequence: PDVDHVFLRF
What is the function of this protein?
Muscle inhibiting agent.  Involved in the neural control of the visceral muscles of the heart, accessory glands and oviduct.  May be involved in the regulation of saliva secretion.
What are the official names of this protein?
SchistoFLRFamide, Cardioexcitatory neuropeptide, PDVDHVFLRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPF_NITOC
Sequence: MRTRVKFCGITRREDAIQAIRLGADAIGLVFYPESPRAVSPQQAYQIVRELPPFVTVVGLFVNAASCYLQQILDKVPIDILQFHGEESPEECGYYGRSYIKAIRMAEGVDLPSLARSYESASALLLDAYQAGVPGGTGRAFDWRRIPKNFSKAVILAGGLTPENIAQAVRQVRPYAVDVSGGVERIKGVKDAAKMAAFMRGVDSVN
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: VP3_SVM93
Sequence: MAPTQSQSKATTQWSLTRLAQQVRPHPTLLLLIRSNPMGPHSAWSWLLPLVQSNPMSLRQYATALQSFVLLLGTTGCPRELFLDLYRFIPTLTRTLLTSLGCGPGGAVVLRSGYRSLVLACSLGASLLLSYHQGLIPRPSGTQACCLTLSLMLASLSQFLS
What are the official names of this protein?
Uncharacterized protein VP3.
What is the protein family that this protein belongs to?
Belongs to the sapovirus VP3 family.
Protein: YNID_SHIBS
Sequence: MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG
What are the official names of this protein?
Uncharacterized protein YniD.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECO_PELPB
Sequence: MIVKTRAVILREIKYRDQSKICSIYTREFGKMSIIIKGARNPKNRLSGLFSAGNVVDLVLYKKSSRDIQLATDGNLVLSPMVPEPDLERFAILYRIIDFVRHTTENDEKNLPLFTLLTGTLEQLYHTNVNFQQLYAWFLLRFVSLLGFQPSLRTCVFSGEELLPAIEALQLTELYFVMNPGGLALPKAAGSSLAKKQLIPVRLAMLLSALAATRLPAGDSIKADPREIEDLWNLLQEYCSLHLEHARGRKNLDIVSQILLK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: IF3C_EUGGR
Sequence: MVRSSCLQCDQPSQGSNSTFGCGGPLAAVCATGLLVLVLYSPSSQTANWSAQGISTKALYPAVPVPSTLLPGSAPAKHQLHVWRAHAMSEATTNNSFKQSLFGYNAISSIWLQLAGVAATFFAFGALMAAVTQRKEIAVFSASGQAAEPEGAEPLKRPFPSPAAKPKPLFSTPANSFSNIFQAPPSLRTDSTYGRGPRSTSFTDISNWPSNNALRNPQSVIDIGGGVDFLGDRSPGNPFTRLRGSPSSTLSNLGMGLGLGLGKGKGFGKGFGKGRGFPVEEEVEEEQEVLSWADRRRALADPDAPPMNEDIKYPQLRLVRAVPGGRDEKLGVMSRQEALELAEAEDIDLVLVSIDTDPPVAKLVNYSKLKYESEKKKKDSHKKGKVKEVKELKVSHKIGQHDYDVRVKQARKFLEGGHRIKVSMEFKGRENQFVEIGRAVMKRFQNDLADMGKADAVPKKLGTRLILNLAPAGEALKVIAERRAERDRKAAAEEEGEGDDLDFVDENEDEDVEGEGEEEEAEELEEETAEGTEVPTRS
What is the function of this protein?
Involved in chloroplast protein synthesis.  It enhances the poly(A,U,G)-dependent binding of the initiator tRNA to chloroplast 30S subunits.
What are the official names of this protein?
Translation initiation factor IF-3, chloroplastic, IF-3chl.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YH7H_SCHPO
Sequence: MVGKSKNRAHKNIRARSCLRCRRRKVKCDRQYPCSRCKESEESCTYGVNEQAVQLLEEPLSRPITRETDSSAHQETRTRLEENNLPKTQKFGFVDWKTILKSSAEFQGIVQRDPESRLREALETDPKLKKRLECILETIPPWDVCESLLKVYANTFNVTNYILDFEQADKLLSDLKNSNHVFATSIILIVTAIAVALSLESFPSNIERYFSAVNHSAIELSDALNSKIDDFLNEEVIFRLWRNIDRIRLHAIRAQLCMRNQFRSMNTDLCYAIHYACFVNPIFQNTDTEYEANMEVWLSICEIDALECVLRSCQPWVQHDIYGKLLSQRKMGSDVISYEFHSLLGQLLTCGLEIYKAIHTSTVNEFVNSIQFYESQLSLVLMEIESKFSNIDGSDIHFRYLFLKTVFWTVRKNLYQGFITVSRTLVPNYPDIVQKLGQTSIQLSRLISNSMDCFEKYGWLKAMLILVTHTFLIIHVCSERGYDVPKDFWNVTASVQATLEEKKYPGIVWERIHYVLNIYTTINSVEPELSEDHGDLDDQNLFQVFTDIFDFNFNFPLPNL
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C16G5.17.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: TALY_CERS4
Sequence: MLAMSPPKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGASGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
What is the function of this protein?
Catalyzes the non-oxidative deamination of L-tyrosine.  Has very low phenylalanine ammonia-lyase activity (in vitro).
What are the official names of this protein?
Tyrosine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: VATA_ASHGO
Sequence: MAGALENARKEIKRISLEDHNENEYGQIYSVSGPVVVAENMVGCAMYELVKVGHHNLVGEVIRLDGDKATIQVYEETAGVTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEQSQSIYIPRGVDAPALSREVKWAFKPGKLGVGDHISGGDIFGSIFENSLLEDHKILLPPRARGTITWIAPAGEYTVDETVLEVEFDGKKYSYSMFHTWPVRVPRPVTEKLSADYPLLTGQRVLDSLFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSDAIIYVGCGERGNEMAEVLMEFPELFTEVNGRKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRVGSVSIVAAVSPAGGDFSDPVTTSTLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKYYDSNYPEFPVLRDRIKEILSNAEELEQVVQLVGKSALSDKDKIVLDVATLIKEDFLQQNGYSTYDAFCPIWKTYDMMKAFVSYFDEAQKSVSNGANWAVLSEATGDVKHAVSSSKFFEPSRGEREVHAEFEKLFASIQERFAESTD
What is the function of this protein?
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Note=Membranes of various intracellular acidic compartments.
Protein: C5AR2_RAT
Sequence: MLNDTTSKDYEYEYDQEQYSDLLNVPVDCPAGNCFSNDAYLIVLLGLYSVIFLVGVPGNTLLAWVTWKESRHRLGASWFLHLTMADLLCCVSLPFLAVPIAQKGHWPYGTAGCWLLSSITVLSMYASVLLLTGLSGDLFLLAFRPSWKNADQRTCGVRVVQVSSWMLALLLTVPGAVYRKLLQEHYPPRLVCGTNYGGSVTAEVTITTVRFLFGFLVPLVFMASCHGILQRQMARRHWPLGTAVVVGFFICWTPFHLLRVIIAVASSHSPLLAWALEAEPLVTGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALRDLQDEEESAVTKVSTSQEMVSEMPV
What is the function of this protein?
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively.  Couples weakly to G(i)-mediated signaling pathways.
What are the official names of this protein?
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CEP2_EBVG
Sequence: MASAANSSREQLRKFLNKECLWVLSDASTPQMKVYTATTAVSAVYVPQIAGPPKTYMNVTLIVLKPKKKPTYVTVYINGTLATVARPEVLFTKAVQGPHSLTLMYFGVFSDAVGEAVPVEIRGNPVVTCTDLTTAHVFTTSTAVKTVEELQDITPSEIIPLGRGGAWYAEGALYMFFVNMDMLMCCPNMPTFPSLTHFINLLTRCDNGECVTCYGAGAHVNILRGWTEDDSPGTSGTCPCLLPCTALNNDYVPITGHRALLGLMFKPEDAPFVVGLRFNPPKMHPDMSRVLQGVLANGKEVPCTAQPWTLLRFSDLYSRAMLYNCQVLKRQVLHSY
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid.  Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.  Activates the AP-1 pathway and enhances EBV reactivation and virus release.  Inhibits type I IFN-induced TYK2, STAT1 and STAT3 phosphorylation, thereby impairing type I IFN signaling and counteracting the ability of IFN-alpha to suppress the reactivation of EBV.  Recruits SHP1 phosphatase to dephosphorylate STAT1.  Mediates STAT2 ubiquitination and proteasomal degradation.  Also suppresses type II and type III IFN signaling.  Contributes to G1/S arrest in the host cell.  Acts as an miRNA regulator that interferes with the function of RISC in miRNA-mediated mRNA silencing.  As a result, SUMOylation is increased.  When encapsulated in the exosomes released by EBV-infected host cells, may facilitate the infection in recipient cells.
What are the official names of this protein?
Cytoplasmic envelopment protein 2, Tegument protein BGLF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Protein: SODC_CANLF
Sequence: MEMKAVCVLKGQGPVEGTIHFVQKGSGPVVVSGTITGLTEGEHGFHVHQFEDXTQGCTSAGPHFNPLSKKHGGPKDQERHVGDLGNVTAGKDGVAIVSIEDSLIALSGDYSIIGRTMVVHEKRDDLGKGDNEESTQTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RISB_ARTS2
Sequence: MSGHGAPEIDLTTLNPAETSQLKLAIVAASWHTQIMDGLLDGALRAAKDAGISEPTVLRVPGSFELPVAAARLAKHFDAVVALGVVIRGGTPHFEYVCEAATMGLTDVSVNTGVPVGFGVLTCDTEQQGLDRAGLPGSKEDKGHEAVTAALATAVTLKQYS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: YACL_ECOSM
Sequence: MDYEFLRDVTGVVKVRMSMGHEVIGHWFNEEVKENLALLDEVEDAARTLKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: SYC_SYNJA
Sequence: MTLVVYNTLTRRKEVFQPFGGSESISADEAAGGEKPLVRMYVCGVTVYDLCHLGHARTYVVWDMVRRYLECRGYRVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFQDMDRLNIKRADLYPRATRSLRAMFELIQSLELKGFAYRVRDPLAPQGETPAYDVYYAVRKFPDYGQLSGRKLEELEAGASGRVGEEGAGKRDPFDFALWKAAPPSEPGFESPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPLAKYWLHNGFVNVNGQKMSKSLGNFTTLRQALALYHPMALRLFLLQTHYRSPIDLTEAAMEAASHGWETLQKGIHCAQQFGQGGSPDSEAMRAFQTAMDDDFGTPGALALAFELAKELIREHNLLTHQGHTHLQPHLLRQKGAALLEILATLGFCWPQPAQGSEKAAANGELAKLPPLEDARIEELVAQRTAARKAKNFAEADRIREQLKALGITLIDQKDGTTRWLRQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CORK4
Sequence: MSEPIKLHDLRPAKGANKPKTRVGRGEASKGKTAGRGTKGTKARKQVSAAFEGGQMPIHMRLPKLKGFKNPNKVTYQVVNVADLQKHFENGGNVTIADLVSAGLVRAKQPVKVLGDGEITASVNITATKFSASAKQKIEAAGGSVTETK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HTPX_STRP8
Sequence: MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLVLALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFIIEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAVALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQLAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKRSFSSLFSTHPPIEERIERLKNM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_BURCJ
Sequence: MENTQENPATPSAEDIGSEKQAAQGAAPAAEAADAALAEAQAKVAELQESFLRAKAETENVRRRAQDDVSKAHKFAIESFAEHLLPVLDSLEAAVSDTSGDIAKVREGVELTLRQLTSALEKGRVVAINPVGEKFDPHQHQAISMVPAEQEPNTVVTVLQKGYMIADRVLRPALVTVAQSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOW_BACVZ
Sequence: MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFMQIQLESINEPIETIRPLPVAFHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAEARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAFTHNMPENSRIKEAHAIAAKVCAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCIHFLEKQPVFIQREENI
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: MURD_BRUME
Sequence: MIPITALKDKTVALFGLGGSGIATAKAIVAGGARIIAWDDNPDSVARAQSAGIATGDLRQADWSQFAVFVLSPGVPLTHPQPHWSVDLARAAGVEIIGDVELFVRERNHIAPDCPFIAITGTNGKSTTTALIAHIIKATGRDMQLGGNIGTAILTLELPCADRFYVVECSSYQIDLAPSLNPTAGILLNLTPDHLDRHGSMENYAAIKERLVAASGTAIIGIDDAYCQAIADRLHGAGIRVVRISKEKHLDRGYFADGAKLLWAQDGEIDEIASLEGIGSLRGAHNAQNALAAIVACLSAGLSLEEIHAGLKSFPGLAHRMEQVGRRGKVLFVNDSKATNAEATAPALSSFPQNIYWIVGGVPKAGGINSLTAFFPRVAKAYLIGEAAAQFAATLGGAVPFEISDTLAAAVAHAAGDAGNDAAPEPVVLLSPACASFDQFQNFEKRGDAFRDAVLALPGVMPMRGES
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y425_SYNP2
Sequence: MKIRETGTRQQHNLRRARIGCVILKKNVTFTMGIRFSRWLVGCGVAIAFGVLSPSVTWANPQLNALLEQGNEQLTNRNFAQAVQHYRQALTLEANNARIHGALGYALSQLGNYSEAVTAYRRATELEDDNAEFFNALGFNLAQSGDNRSAINAYQRATQLQPNNLAYSLGLATVQFRAGDYDQALVAYRKVLAKDSNNTMALQNSLTSLLQLGRNQEAAVLFPDLLRQRPNDAELRIKAAVTWFGLNDRDQAIAFLEEARRLSTRDSAMQIRVGKIYETQNLLPQAIAAYEQASFVDPQSREAFALYGSAAMKTEDYINAIIAYRALTELSPTDPAAFYNFAVALQGRRRSREALEALEMARDLYQQRGDRRGVNITESLMAAIEEG
What are the official names of this protein?
TPR repeat-containing protein SYNPCC7002_A0425.
Protein: Y1813_MYCTU
Sequence: MITNLRRRTAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGASGKAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDAVNRLEGGRIVNWACN
What are the official names of this protein?
Uncharacterized protein Rv1813c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1269c.
Protein: PUS10_ARCFU
Sequence: MNLCRECYGIIGEGVVAEKCEACCNAFDRVEEFAEEIVKKMSEYEFETFNVGSRVWGSLKALQEYLSLKGIEYEIKQRFNTKLARAIEEKTGSKRTLNPDITVLFDLETFTFELQIRPVFIYGRYLKRVRNISQTRWLCGYCNGEGCEVCNFTGKKYVSSVEELIAMPAVRLFKARDAKLHGAGREDVDARMLGTGRPFVLEVIEPRKRFVDLKELEEAINSQKWVAVRDLEYTDAEKVREVKTERHRKTYRAKVVFEEKVERERLIEALESLKGEIRQRTPMRVSHRRADRVRVRRLYDARLIHHTGRVAVVEFEAEAGLYIKELVSGDNGRTRPSLAEKVGVNARVDRLDVIAVS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: TBRG1_RAT
Sequence: MSVLSGLASEPRTPLSSKARMKRLPKKNQNEKYRLKYLRLRRAAKATVFENAAVCDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLAYGVTSSVGTIQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKRKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPRNTIVGSSADACYEELLRAISAATGKLMPNPLSCGADFFGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPENDAAMSLEAFPTQTFDDDHEDSILPGSLDLPELQHEAFVSSYQPEFLTHEPLVDTDLQHLKSPSQCSPIQSSD
What is the function of this protein?
Acts as a growth inhibitor.  Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis.  Redistributes CDKN2A into the nucleoplasm.  Involved in maintaining chromosomal stability (By similarity).
What are the official names of this protein?
Transforming growth factor beta regulator 1.
What is the protein family that this protein belongs to?
Belongs to the TBRG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H4_PIG
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CADM1_RAT
Sequence: MASPVLPSGSQCAAAAAVAAAAAPPGLRLRLLLLLLSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNKELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVQIQMTYPLQGLTREGDAFELTCEATGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNTVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTTTILTIITDTTATTEPAVHGLTQLPNSAEELDSEDLSDSRAGEEGAIGAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI
What is the function of this protein?
Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner.  Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner.  Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ T-cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo (By similarity).  In mast cells, may mediate attachment to and promote communication with nerves (By similarity).  CADM1, together with MITF, is essential for development and survival of mast cells in vivo.  By interacting with CRTAM and thus promoting the adhesion between CD8+ T-cells and CD8+ dendritic cells, regulates the retention of activated CD8+ T-cell within the draining lymph node.  Required for the intestinal retention of intraepithelial CD4+ CD8+ T-cells and, to a lesser extent, intraepithelial and lamina propria CD8+ T-cells and CD4+ T-cells.  Interaction with CRTAM promotes the adhesion to gut-associated CD103+ dendritic cells, which may facilitate the expression of gut-homing and adhesion molecules on T-cells and the conversion of CD4+ T-cells into CD4+ CD8+ T-cells.  Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly.  May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons.  May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa (By similarity).
What are the official names of this protein?
Cell adhesion molecule 1, Synaptic cell adhesion molecule, SynCAM, Tumor suppressor in lung cancer 1 homolog, TSLC-1.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse. Postsynaptic cell membrane. Note=Localized to the basolateral plasma membrane of epithelial cells in gall bladder.
Protein: RNJ2_STAES
Sequence: MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGVDIVIPDIQYVIENKERLKGIFLTHGHEHAIGAVSYVLEQIDAPVYGSKLTIALVKEAMKARNIKKKVRYYTVNHDSIMRFKNVNVSFFNTTHSIPDSLGVCIHTSYGSIVYTGEFKFDQSLHGHYAPDLKRMAEIGDEGVFALISDSTEAEKPGYNTPENIIEHHMYDAFAKVKGRLIVSCYASNFVRIQQVLNIASQLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPINEVENYPKNEVIIIATGMQGEPVEALSQMARKKHKIMNIEEGDSIFLAITASANMEVIIADTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMLNIMKPEYFVPVQGEFKMQIAHAKLAAETGVAPEKIFLVEKGDVISYNGKDMILNEKVQSGNILIDGIGVGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEELLKEAEEKVRKIVEEGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 2, RNase J2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.