PharMolix/UniProtQA huggingface dataset:
Protein: CRVP_GLOBL
Sequence: MIVFIVLPILAAVLQQSSGNVDFDSESPRKPEIQNEIVDLHNSLRRSVNPTASNMLKMEWYPEAAANAERWAYRCIEDHSSPDSRVLEGIKCGENIYMSPIPMKWTDIIHIWHDEYKNFKYGIGADPPNAVSGHFTQIVWYKSYRAGCAAAYCPSSEYSYFYVCQYCPAGNMRGKTATPYTSGPPCGDCPSACDNGLCTNPCTQEDVFTNCNSLVQQSNCQHNYIKTNCPASCFCHNEIK
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  Since high potassium-treatment activates voltage-gated channels and caffeine exposure activates ryanodine receptors, this toxin may target L-type voltage-gated calcium channels (Cav) (and not ryanodine receptors) on smooth muscle (PubMed:12047379).  This toxin also shows a little inhibition on cyclic nucleotide-gated CNGA1 channel (PubMed:12646276).
What are the official names of this protein?
Cysteine-rich venom protein ablomin.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABA_SHEWM
Sequence: MSKANSFNKEDLIACGHGELFGEHSPRLPIDNMLMIDRITKINADGGEFGKGEIVAELDINPELWFFKCHFDGDPVMPGCLGLDALWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPDAKKVTYKLTVKRKVYRKLVMGIADAVMEVDGREIYSATDLKVGIFKDTSSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y123_OSHVF
Sequence: MAASILQAENIELRKRLNAVCEYVDMEAKCETAAGKIFYKHCYQTAKNGGTGTGLICMNPDMLHAMELFDEELSLKDNWTNFKNILIKINIGQVITIHGQAIPVNPNHYRNGEGYYLTLVAPKKTEAIDDAVPLLDTEQLYRFIMCYHEIKMDLIDWIERSASLSGLQVKLDSANHALNMAEYVMDTIADPTNEDIVLQCISEVNEMDNAKFGHFLGKLNDLLDSPELKPNSCSDIARKQLRYFYRVDKDSAVNYIADNYFNLDISFKEFLDNFMLKTFYPELNCKNIMFYPIGAKKIVFCMK
What are the official names of this protein?
Uncharacterized protein ORF123.
Protein: MDAR_PEA
Sequence: MVHSFKYIIIGGGVSAGYAAREFVKQGVHPGELAIISKEAVAPYERPALSKAYLFPESPARLPGFHTCVGSGGERLLPEWYSEKGIQLYLSTEIVSADLAAKFLKSANGEHFDYQTLVIATGSAVIRLTDFGVIGANAKNIFYLREVDDADKLYEAIKRKKNAKRVVVGGGYIGLELSAVLKLNDLDVTMVYPEPWCMPRLFTSEIAAFYEGYYANKGINIIKGTVAVGFTANSDGEVKEVKLKDGRVLEADIVIVGVGGRPQISLFKGQVEEQHGGIKTDSFFKTSVPDVYAVGDVATFPLKLYNDVRRVEHVDHARKSAEQAAKAIFAADVGKSVEEYDYLPYFYSRSFDLSWQFYGDNVGETVLFGDNDPASSKPKFGTYWIKEGKVVGAFLEGGTPDENKAIAKVARAKPAVEDVNQLAEEGLSFASKI
What is the function of this protein?
Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process.
What are the official names of this protein?
Monodehydroascorbate reductase, MDAR, Ascorbate free radical reductase, AFR reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAI1_MOUSE
Sequence: MMAEQVKCASPVAASGAGPGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLLLLQPPPPSAPPPAGACSPLATHRAPASTTSPGPGALGPAFPGTYCLPSPAPSLLCSLQPADAPFVYSKPAAGFFGGGGSPEPGTAGTPPGEAATPPLPPPTLLDEVEPLDLESLAAWSEEDDYTWLYVGSSKTFTSPEKSPSPLQWCRHVLDNPTPEMEAARRSLRFRLEQGYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRNSSSVSLSSGKKGTCSDQEYDRYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRDCRRSPSTQYFPSNNFQQPQYYPPQAQTADQQPNRTNGDKLRRSMPNLARMPSTAAASSNLSSPVTVRSSQSFDSSLHGAGSGVSRVPSCIPSPGQIQHRVHSVGHFPVPIRQPLKATAYVSPTVQGSSSSGSSGSSGGSGSGMPLSNGTQLYSTTGIPTPNKAAASGILGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY
What is the function of this protein?
Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation.
What are the official names of this protein?
SLAIN motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLAIN motif-containing family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules.
Protein: GMHA_LEPBA
Sequence: MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASHIAAELVIRYKSGNERKAIPAIALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGLTTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADVEIIIPSSVTARIQESHILIGHILCSIIEKELFGLD
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BURL3
Sequence: MQFPESWLRTFVDPQLTTDELSHALTMAGLEVESLSKAAPPTSKIVVGRVLEVVKHPDADKLNVCQVDAGTGATLNIVCGAPNVAPGIKVPVALVGAELPPAEEGGKPFAIKLSKLRGVESQGMLCSARELKLSEDHSGLLVLPEDTPVGQDIRETLNLDDTIFEIKLTPNKADCLSVFGIARETAAITGAPLTPVDIRPVRVELDETLPVRIAAPDLCGRFSGRVIRGVNAHAKTPQWMVERLARSGQRSVSALVDISNYVMFELGRPSHVFDLDKIHGGIEVRWGKRGESLKLLNGNTVELDETVGVISDGRQVESLAGIMGGDSTAVTLDTTNIYLEAAFWWPDSIRGRARKYNFSTDAAHRFERGVDYATTVEHVERITQLILEICGGKAGPVDDQSVNLPQRAPVKMRVSRANRIIGVQIGADEIASIFTRLGLPFEREDDAFLVTPPSHRFDIEIEEDLIEEVARIYGFEKIPARPPVATSEMRATNETRRSIHDIRHALAARDYAETVNFSFVDAEWEQDFAGNDHPIRLLNPIASQLSVMRTTLFGSLISVLRHNLNRRADRVRLFEAGRVFLTDAASKAGELTVEGYVQPKRVGALAYGPALDEQWGAETRPVDFFDVKGDLEALLAPAAARFVKAEHPALHPGRSARIEVDGRAVGWIGELHPRLMQKYELPHAPVMFEVDADALIARALPAPTDVSKFPPVRRDIAVVVDQAVEVQALFDEMKKALAEEACRFVQKVVLFDEFRAKSNTSGGLAAHEKSLAFRVTLQDAAGTLQDEVVDQAIQTLVERMARAGARLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_XANC8
Sequence: MSRAPDRIAACFDALRHSGRKALIPFITAGDPSLEATVPVMHALVRAGANIIELGVPFSDPMADGPTIQRSSERALGRGAGLAYVIEAVQEFRREDATTPVVLMGYLNPIEIHGTRRFAETAVAAGIDGVLLVDLPPEEADETRAIFTEVGLALIALASPTTGEARLDMLCSTAQGYLYYVSFSGVTGAADRLDTHAASDRLRQLRARAGAPVVAGFGIKDAASAAAMAVDADGVVVGSALVAALADASDVRSARKRAEDFLQPLRQALDAG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RR7_AMBTC
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGNGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXH_AGRRK
Sequence: MSENELTSGDFTEQNEPFALFAAWLREAEATEPNDPNAVALATVDKDGLPNVRMVLLKGFDSQGFVFYTNFESQKGQEILSQKKAAMCFHWKSLRRQVRLRGLVEVVSDKEADEYYKTRARGSRIGAWASKQSRPLEGRFALEKAVAEYTARYALGDIPRPPHWSGFRIRPLSIEFWHDRPFRLHDRVEFRREVPEGAWEKVRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL10_HAHCH
Sequence: MAIRLEDKKAIVAEVNETASKALSLVIADYRGVTSNKMSELRAKARAESVSLRVVRNTLARRAVEGTEYECAREAFVGPTILAFSMEDPGAAARLLKDYAKENDKFEIKALAVGGEMLGADQIDRLAKLPTRDQALAMLMSVMQAPVTKLARTLNEIPSKVTRAVAAVRDKKQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RDRP_GFKVM
Sequence: MVLTLCFHSDRDHHFLSTLPLAEIRRLAPGGFSVFVPEDLLPHLSPSPSCPTPPLPRELTWSAACNPTNFPHLFRHHRPPPPCTRLTPRPPPPTPAPPSASTLPRVFHGGAPPAAFQPAIDFLHNTIQKDTIASSIIAALNPSLTSSLTLYPYALPPRWPSALNQAGIPATSYGHQSHPHPIHKTIETHLLHEHWANRATLPSTVMFMKRSKFDKLRVSNAALVKSASNFLHLLNPILTARDADRYTHLPLPDTLPSTPLYFMHHSLMYFSPSQIAGLFLAAPFLERLYASLVLPAESTIGSHPFFPSLYRYRTTGEHLHYVLEGNPSSSYTQPLTATQWLTTSSITAGDLHLTVTVLESWFSVHSILITRGVRPLELPRDIISLPSPDAVLLPNPSAFDIPLRSRLVPRDVCESLFVYVRAVRTLRTTDPAGFIRTQSNKAEFDWVTAEAWDHLAQFALLTAPVRPNTYFLPLLSPLAVVRHWLFRKQRPIFATLTLLSASTAAAIPIAIARLRTHSVTQLTILGHHFTPPKILARLPVALKRLIPKRLLPHLPSHLRPPPSWSPVFTLTFSELPKARFLTFPISGQTHTLLRQLHVPAILFAPQRPSRPLIFAGLLIGTVPVLYGAYRWFVSRFDPQTVYNRYSDLLHRPTWHLTFEREPLSCFPTPFLPHPSSHPRRARRLPPLPPAPPLPPQPPPPPPPQPSPHPPLFPASIPSPPPRPSSPPPPATSPASTPALTPIPAPKTAPPLTFPSPTLVAEPDAPVTARPSPLPLAPSRPFSELYPGHYADHSGSFFLQQPLVASSVPYPALDCLLVSCSAASGIPKEDLWATLCHIFPPSDLVSDLGLSTNHLTALAFTYQWLVTLRSGELVQRHGLLSAPFAFEITHTPPVPPATVGHFALSAPLTPTSACLTGGAPSPVISGPKASASLPRARFGPRPEAPRPPLTPPGFTPITEPTPATSPFALAALRFRLNRQPLPIRQVHAYSIALPRAKNLVSNLKNGFDGLVSSLPASDRTNLLPLIQALDHTADFPPARPPVGLIHIAGFAGCGKSYPIQQLLATQTFRHFRVVTPTTELRHEWKRALKLEGPSSWRVSTWETALAKRASVLVIDEVYKLPRGYLDLALLADPTVEFVIILGDPLQGSYNPTNPDSSNHRLIPEEDHLRPFIDFYCLWTRRLPRLVADFFGVPTTNPTRGHLAFASLNTTQSPLLVPSDSMARALTAGGHRAITYAASQGSTYPAPVHIFLDRNSNLVTNHVALVALTRSRSGVHFRPRAQDLPRHPQHLFTAFYKYAIDLLAHEADPSKPRPTPVDVTLLFQQQLRGLTILRDPSFSRITGGATHAFLAHAPLFTNLHGLRPTTFPDNLPTAPTYLARSLPYHQTESYPTSALPHRVFPASTTDWSAADDHPRVNPTFVAETRLPLQSELAPTLPSQPEPSPTYHSPATFETVYPGVDGEALARTFLAATDPLELEIFFRNNWSNQFPFINRPDTVACNPLTLVAPTHNQKQDPTLLHASLAKRLRFRDSTAPYTITAKDQALGYILYHSLQRAYCRSPEPVPFDPVLFASCIAENDFAQLTSKTQATIQANAFRSDPDWRHTFVRIFSKTQHKVNENSLFTSWKACQTLALMHDYLILVLGPVKKYQRILDSRDRPAHLYIHAGQTPHQLSEWCQNHLTPSVHLANDYTAFDQSQHGEAVVLEAWKMRRASIPEPFITLHVHVKTNIECQFGPLTCMRITGEPGTYDDNTDYNLAILYTQYLLHRTPVLVSGDDSLVDRVPPMNPSWPALAPLFALKPKPETSPFGLFCGYFVGPAGAVRAPRALFAKLAIALEDGSLPEKIASYVAEFSVGQSLGDSLWSLIPPELVIYQSACFDLICRHASPQLKLALRLGEVPDWGSLLSQLKLRFLTRPLFALLDAHTRVMVRTHKAHLLPSGHALHPSTEPFY
What is the function of this protein?
RNA replication protein replicates the viral genomic RNA.  The central part of this protein possibly functions as an ATP-binding helicase and/or methyltransferase (Probable).
What are the official names of this protein?
RNA replication protein.
Protein: ASSY_NITMU
Sequence: MNVAQIKKVVLAFSGGLDTSVILKWLQDTYRCEVVTFTADIGQGEEVEPARAKAKQLGVREIFIDDLREEFVRDFVFPMFRANTLYEGEYLLGTSIARPLIAKRQIEIARETGADAVSHGATGKGNDQVRFELGYYALQPDIRVIAPWREWDLTSREKLLKYAEQHGIPVEMKKKEGSPYSMDANLLHISYEGRILEDPAQEPEESMWRWSVSPEKAPDSPEYLDLEFRQGDIVALDGEELSPARLLARLNELGGKHGIGRLDLVENRYVGMKSRGCYETPGGTIMLRAHRAMESITLDREVAHLKDELMPRYAELIYNGYWWSPERRMMQTMIDASQAHVNGWVRVKLYKGNVIVVGRDSKTDSLFDPHIATFEDDQGAYNQMDAAGFIKLNALRMRIAANLRNRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBE_GORGO
Sequence: MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALAHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1080_SULTO
Sequence: MSFRESDILITTAQELPGYKIVEVKGVVIGITVRSRGLGGNIAASFRSLIGGEIKEYVEMAEQARMQALERMIERAKALGANAVISVRFDSNELAQNMDEIIAYGTAVVVTKSI
What are the official names of this protein?
UPF0145 protein STK_10800.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: NUOC_BRUA4
Sequence: MSEEALGELSGYIKERLGDAIEEAKLAYGELTLSVPAASIISVLTFLRDDVQCQFVNLTDISGVDYPQRAKRFDVVYQLMSPRQNQRIRVKVQADEDTLVPSAVPVFVGAEWFERETYDMYGVLFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYNDELKRVVYEPVQLRQEFRNFDFLSPWEGTDYVLPGDEKAKAN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMFO_GEOMG
Sequence: MTDAITIIGGGLAGCEAVWQAAERGVRVTLHEMKPHAFSPAHHLAGLAELVCSNSLRGESLENAVGLLKEELRRAGSLIMAAADATRVPAGGALAVDRELFSAFVTERIENHPLVDLMRGEVADIPSEDIVIVATGPLTSDGLAERIRAITGPNLYFYDAIAPIVTAESLDMTKVFRASRYGKGDGDDYLNCPLNQEEYEGFVDAILAAEKVPARDFEKVVHFEGCMPVEEMAERGRETLRFGPLKPVGLADPRTGEEPHAVVQLRAENREGTMFNLVGFQTKLTYPEQRRIFRMIPGLENAEFVRLGSMHRNTFINAPALLAPTFQLKGDARILFAGQITGVEGYVESAGSGFLAGVNAARLVRGEEPVVPPLATALGALVTHITNADVKHFQPMNVNYGLFPPLEGKVKKKERRGKLAERALAELDRWIGTV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CLOBJ
Sequence: MENRMVTPFDVEDDREQYSLRPTTLKEYIGQKKVKANLDIFIKAAKKRSESLDHVLFYGPPGLGKTTLANIIANEMTGNLKVTSGPAIEKAGDLAAILTSLTDYDVLFIDEIHRLNRSIEEILYPAMEDYALDIVIGKGAAAKSIRLDLPKFTLIGATTRVGLLTSPLRDRFGMLCAMEFYTDEELMEIVVRSAAILNVNICREAAFEIGKRSRGTPRIANRLLKRVRDYCDVKHDGDIDLQGAKAALDLLEVDKEGLDKIDNKILEAIIFNFKGGPVGLETLAYFIGEELDTIEDVYEPYLIQKGFIMRTPRGRVASEKAYNHFGVTKKEEKDNQVSIFNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y1760_MYCTU
Sequence: MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMETPSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTELNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRDRPLWEMWVIEGGARSDTVAVMLKVHHAVVDGVAGANLLSHLCSLQPDAPAPQPVRGTGGGNVLQIAASGLEGFASRPVRLATVVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDMRDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSVHDKSDRPGRNQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGPTLLHDWIQFGGSTMFGAAMRILPHISITHSPAYNLILSNVPGPQAQLYFLGCRMDSMFPLGPLLGNAGLNITVMSLNGELGVGIVSCPDLLPDLWGVADGFPEALKELLECSDDQPEGSNHQDS
What is the function of this protein?
Upon expression in E. coli functions weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA.  Has very weak wax synthase activity, incorporating palmityl alcohol into wax esters in the presence of palmitoyl-CoA.
What are the official names of this protein?
Putative diacyglycerol O-acyltransferase Rv1760, Putative triacylglycerol synthase Rv1760.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: TGT_RICPU
Sequence: MSKFSFNIYHQHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETGADILLGNTYHLMLQPTAERIVQLGGLHKFMNWDKPILTDSGGFQVMSLSKLCKITEEGVSFSSHINGDKYMLTPERSTEIQYLLGSTITMAFDECTPYPATFEEAKTSMQLTTRWANRSRNAFVKREGYAQFGIIQGSVYEELREQSSKDLVELDFEGYAVGGLAVGEGQELMFKVLDYAPDFLPQNKPRYLMGVGKPADIIGAVSRGIDMFDCVIPTRSGRNGQAFTKYGTVNIRNSKYADDNKPLEHDCLCPACRNYSKAYLHHLVRIGEILGSMLMTWHNLTYFQNLMSRIRAYIKLGKDFDFDS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CFA61_HUMAN
Sequence: MSVLTSPRGKVEVVHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPNWNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASEEALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKSILEDLDRYNKARKDPDGTLLQAFVAEVAEQIVGIAVIRNEMDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYTGKVPCNHFTLNEEEDCFKALIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSVESAVADALGAAGVTMYRDAILAQWNDGLHPDPIYSASFTTPTKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDSRLVIDTNFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLHLFDPTLEPVTEPPANLDRLIPMYKGAKIQGGILPGSYHYLHIAKPAIPTPLEVQMAQPNYGLELVTGSAKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFGQHEQLLNNLCARYDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKEEEDLPSIEQLAHQIEDEEINPTEKPRQYLKRVFEESIYKTLVERSTLDYLHYNRYHLPMYAWPGIV
What is the function of this protein?
May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
What are the official names of this protein?
Cilia- and flagella-associated protein 61.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ASK4_ARATH
Sequence: MAETKKMIILKSSDGESFEIEEAVAVKSQTIKHMIEDDCADNGIPLPNVTGAILAKVIEYCKKHVEAAAEAGGDKDFYGSAENDELKNWDSEFVKVDQPTLFDLILAANYLNIGGLLDLTCKAVADQMRGKTPEQMRAHFNIKNDYTPEEEAEVRNENKWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 4, AtSK4.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SURE_CAMJE
Sequence: MKEILITNDDGYESEGLKKLIKMLTKEFKAKITIVAPASEKSACSHSITLTKPLRFVKVGKRFYKLDDGTPADCVYLALHALYKKRLPDLVISGINKGANVGEDITYSGTCAGAMEAVLQGIPAIALSQFYKKSEKELDYKNALQITKKIIQNIFDKGFPLEKKEFLNINFPAKSKIKGIKICKAGKRVYNFEAHSNVNPRGVEYYWLAAANLDFEDEKNSDIALLKKGYATITPIMLDLTAYERMKKVKKWLKANDE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_BACVZ
Sequence: MSIKQYSQEQLKQMALVEIAHEIFSEHKKPVPFQELLNEMISLLGVTKEELGDRIAQFYTDLNIDGRFIALSDQTWGLRSWYPYDQLDEETQPTVKAKKKKAKKVVEEDLDLDEFEEVDEDDIDLDEIEEDIDLEADSFDDEDIDEEDDDELEIEDEMIEEDEEDYDDEEEDRKD
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: NTPPB_SHEDO
Sequence: MKTTLILASTSPYRQQLLQKLTPNFTCVSPEVDETPLADETAQALVVRLAQAKAIAGAERYLAELGLSNLHTAAEALVIGSDQVAVIDGAIIGKPLTQANAINQLQQASGKAITFYTGLAVYNSHSHKMTCEIVPFTVHFRTLSLAQITYYVETELPLYCAGSFKSEGLGIALFERLEGDDPNTLIGLPLIALIDMLAEHGETVLS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.