PharMolix/UniProtQA huggingface dataset:
Protein: DUSP_RACVI
Sequence: MDKKSLYKYLLLRSTGDIHRAKSPTMMTRVTNNVYLGNYKNAMEAPSSEVKFKYILNLTMDKYSFTNSNINIIHVPMVDDTSTDISIYFDDITAFLSKCDQRNEPVLVHCAAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN
What is the function of this protein?
Serine/tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated host STAT1 and blocking interferon (IFN)-stimulated innate immune responses.  Dephosphorylates the OPG144 protein.
What are the official names of this protein?
Probable dual specificity protein phosphatase OPG106.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Approximately 200 molecules of H1 are packaged within the virion and are essential for the viability of the virus.
Protein: EUTC_SALPB
Sequence: MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQCAAPTVTESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVMNPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: EX7L_CLOBM
Sequence: MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFALENGMDVVALGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDAHKKEIPKFSKKIGVITSPTGAAIKDIINVTKRRNKGIELLIYPALVQGTDASKTLIEGIKTLNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDFTIIDFVSDRRAPTPSAAAEIAAFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQKIEANSPTNIIANEYRNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKELNKINIIFKDGRAKLSIKYIEEF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERG13_CANAL
Sequence: MVMTNSPQNIGIKGIEVYIPGQAVNQSDLEKFDGIPQGKYTIGLGQTNMAFVNDREDIYSISLTVLSRLIKNYSIDTNKIGRLEVGTETLLDKSKSVKSVLMQLFPGNNDIEGIDTVNACYGGTSSVINAINWIESSSWDGRDAIVVAGDIAIYDKGAARPTGGVGAIALLIGPDAPIVFDSIRGSFMEHAYDFYKPDFTSEYPVVDGHFSLSCYVKAVDNCYKNYSKKITGDANKTVGVYDHFDFSAFHVPTCKLVTKSYARLLYNDYVSNPSKFADLIDETTRKHIDGLTYDESLTDKILEKTFVGLAKDETKKRVQPALQVPTNTGNMYTASAWVSLASLLYYVGSDNLKNKRISIFSYGSGLASTLLSVTVKGDVSAITKVLDFDYKLGDGRKIQSPEDYLAAIELREKAHLQKSFKPQGSTDNLSQGTYYLTEIDDKFRRAYAIKE
What is the function of this protein?
Hydroxymethylglutaryl-CoA synthase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  ERG13 condenses acetyl-CoA with acetoacetyl-CoA to form hydroxymethylglutaryl-CoA (HMG-CoA) (By similarity).  The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase ERG10 that catalyzes the formation of acetoacetyl-CoA.  The hydroxymethylglutaryl-CoA synthase ERG13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.  The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase HMG1 finally reduces HMG-CoA to produce mevalonate (Probable).
What are the official names of this protein?
Hydroxymethylglutaryl-CoA synthase, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
Protein: YIPL4_ARATH
Sequence: MGRVFMVDLEGNIYICKLCKTHLSTDQDIMSKSFQCKNGRAYLFNNVVNVSVGEKEDRMMITGLHNVVDIFCVGCGSNVGWKYEFAHEKSQKYKEGKSVLELYKISGPHDSNDLVSDGDDA
What are the official names of this protein?
Protein yippee-like At3g55890.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: HEM1_CALS8
Sequence: MLWVIGINHKVEVDIRQKFSLTKTKLQEKLISLKKLADEVIILSTCNRTEIYFFSEEYVDIEKIFTELDWDRRYMPLFYIYKDKDCIKHLFEVVCGFDSLLIGEEQIVAQVKEAKDIAKQVGGKNPVLERLFEVALKCSKEFRTKARLNEHPITIASVVGKVLKESNIRKIAIIGLGNIGFLFCNYFKNSDVDKVFLIGRKNERIDQFVKLYPGKFEYSDKKDAISEAQCLICSTSAPHAVVHKDDIPDGKNLLIFDLAVPRDVDVEVYKLPNVKVIDIDQVHKMDATSREIRISKMQENYNIIEKYIDEFIEWLGFRQYRNLIIEVKRHAEQLCKAQVKYLKNVDSREREEVERLLIRMANLYIDRAIEVLREAHKEGSGEICSNLIKRIFLK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: AZOR2_COLP3
Sequence: MITLLHIDTSARRTDNDVKEYNSISKSLAAHFMDKWITLNSKDKVIYRDLGLNPPDFISQDWIAAVFTPDEKQSEEQKSLLTLSDTLIDEVDQADIIVISSPMYNYGMPAVLKAWFDQVVRINKTFTFDLARGDFPIEPIMSGKKLILISSSGEFGFEIGGIREKMNYLAPHVETASKYLGVEEFYEIKSEYQEFADARHEESLSNAYRGVEELVKQLV
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: GDL88_ARATH
Sequence: MRPEIVLFGDSITAQSFRSGGWGSALADAYSRKADVVVRGYGGYNTRWALFLLHHIFPLGSSSPPVATTIFFGANDAALKGRTSDRQHVPVEEYTDNVRKIVQHLKKCSPTMLIVLITPPPIDEAGRQSYAESIYGEKAMKEPERTNETTGVYAQHCVALAEELGLRCVNLWSKMQETNDWQKKYLSDGLHLTPEGNGVVFDEVSRVFREAWLSPEEMPFDFPHHSHIDGKNPSKAFEERCL
What are the official names of this protein?
GDSL esterase/lipase At5g62930.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
Protein: APOC4_TAPTE
Sequence: MSLPVRRASPLLSLCFCVLVLAWAVACQQEVPAGSPSPPPEPASSPWGLVHSKVKEFLEPLVTKTRERWQWFWDPGAFQGFVQTYYDDHLRGLGSRARAWLHGSKDSLLSKAYNLCPQLLCGDGDQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPX1_MYCTO
Sequence: MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAEATDSSGKITKRGADKLISTIDEFAKIAISSGCAELMAFATSAVRDAENSEDVLSRVRKETGVELQALRGEDESRLTFLAVRRWYGWSAGRILNLDIGGGSLEVSSGVDEEPEIALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELAEPSVTVLEAGSPDLAVATSKTFRSLARLTGAAPSMAGPRVKRTLTANGLRQLIAFISRMTAVDRAELEGVSADRAPQIVAGALVAEASMRALSIEAVEICPWALREGLILRKLDSEADGTALIESSSVHTSVRAVGGQPADRNAANRSRGSKP
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.  Required for long-term survival of M. tuberculosis in necrotic lung lesions.
What are the official names of this protein?
Exopolyphosphatase 1, ExopolyPase 1.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
Protein: CYSD_VIBA3
Sequence: MDQERLTHLKQLEAESIHIIREVAAEFDNPVMMYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTDWKFREMIEFRDRTAEKYGFDLLVHKNPEGIEMGCSPFVHGSSKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKNHTWDPKNQRPELWHTYNGQVNKGESIRVFPLSNWTELDIWQYIYLESIDIVPLYLSDKRPVVERDGMLIMVDDDRMELQEGEVIEEKSVRFRTLGCYPLTGAVESEANTLTGIIEEMLVATSSERQGRAIDHDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: CCA12_ARATH
Sequence: MSSSSRNLSQENPIPRPNLAKTRTSLRDVGNRRAPLGDITNQKNGSRNPSPSSTLVNCSNKIGQSKKAPKPALSRNWNLGILDSGLPPKPNAKSNIIVPYEDTELLQSDDSLLCSSPALSLDASPTQSDPSISTHDSLTNHVVDYMVESTTDDGNDDDDDEIVNIDSDLMDPQLCASFACDIYEHLRVSEVNKRPALDYMERTQSSINASMRSILIDWLVEVAEEYRLSPETLYLAVNYVDRYLTGNAINKQNLQLLGVTCMMIAAKYEEVCVPQVEDFCYITDNTYLRNELLEMESSVLNYLKFELTTPTAKCFLRRFLRAAQGRKEVPSLLSECLACYLTELSLLDYAMLRYAPSLVAASAVFLAQYTLHPSRKPWNATLEHYTSYRAKHMEACVKNLLQLCNEKLSSDVVAIRKKYSQHKYKFAAKKLCPTSLPQELFL
What is the function of this protein?
Involved in the regulation of male meiosis progression.
What are the official names of this protein?
Cyclin-A1-2, G2/mitotic-specific cyclin-A1-2, CycA1;2, Protein TARDY ASYNCHRONOUS MEIOSIS.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SERC2_HUMAN
Sequence: MGACLGACSLLSCASCLCGSAPCILCSCCPASRNSTVSRLIFTFFLFLGVLVSIIMLSPGVESQLYKLPWVCEEGAGIPTVLQGHIDCGSLLGYRAVYRMCFATAAFFFFFTLLMLCVSSSRDPRAAIQNGFWFFKFLILVGLTVGAFYIPDGSFTNIWFYFGVVGSFLFILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTEPSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPEQKCNPHLPTQLGNETVVAGPEGYETQWWDAPSIVGLIIFLLCTLFISLRSSDHRQVNSLMQTEECPPMLDATQQQQQVAACEGRAFDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYKPGETRKMISTWTAVWVKICASWAGLLLYLWTLVAPLLLRNRDFS
What are the official names of this protein?
Serine incorporator 2, Tumor differentially expressed protein 2-like.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL31B_ECO8A
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGS
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RIBD_MAIZE
Sequence: MASSLVSRPHLTQRPVRAATLASATRPRLAAGALSGRCQAQAAGDLDDAHYMRRCVELARKAAGHTSPNPMVGCVIVRDGRVVGEGFHPKAGQPHAEVFALRDAGNLAENATAYVSLEPCNHYGRTPPCTEALINAKVKEVVVGMTDPNPIVASKGIEKLQGAGISVRVGVEEALCRKLNEAYIHRMLTGKAFATLRATLSMNGIITNQIGKGADQSGGYYSQLMKEYDGVIISSDLAKMSALPLSREAGTNQPLCIIIAQGESSRLHIPSLSQEHASRAIVLADSPVTVEPAGVEVAVFRQIDLESILQLLAQRGLCSVLVDFREAGESFASLLNDFQEDKLVQKVVVEVLPFWLASDGLSNLAFGGSQSFPLKNLELRDVNGSVLLEGYV
What is the function of this protein?
Monofunctional pyrimidine deaminase involved in the riboflavin biosynthesis pathway.  Has also a reductase domain that lacks catalytically essential substrate-binding residues (By similarity).
What are the official names of this protein?
Riboflavin biosynthesis protein PYRD, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISCA_SHIDS
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PCARE_MOUSE
Sequence: MGCTPSHNVIVNSVAKSGIQFFKKPKAILPGCQWGSPKCPIPLLVQSSTFCDSGGELHLGERLVEETVSSSKKLQAMAEGVRQLPKAMEGLIPESQTFQVNKPQGHRATDISFRTEGSHGTQEVDFSGKESKENTPQETSKGNRESVCHQPDSQDHCRQSATESKGRVDFPEPLVKAHQHAYAYLHTSLSRYEAIVRLVQQASQTWGLLRPMLNFLLLCFEEAGQLLSEISKDGDVLLQEVRGDLAWPLRKGEPWEQHPDLLQQLLQYTVSKLRALHGTVAALTGSFLEGSSSCLRSTAGHLEGKLSTKRGIDECLLRALGQLESLTSSHGDAGLLGPPLCSEDSGIGADNESVHSVEKLGKQASWDFAAELGEWKPGTAAQVEARPSGHAWQEGPYWTGSDRPQDCPLSSPRIAKVQPAVQDEARSASTSGAGAEAVTSGPSEAAESLPWDSLGAEIPVRTPLSRSSGLTDAPSLSEEEDCSPEEEDELSSTDLHPEPQKALPSRPRSSPDTRESLFQPYSKELRNPQAQEMILKMKEAISERIKFVPEPSRPQDWTEEEEGGTVVPPRPRSVSGSRGGPERQRRSQSEGCLKSHVEDPTLQELRRVQTDLSRRLEVFYALGATRQGQSRERCLPSRASVLWPPTNCRVSPSSAISKFKASLTQNFSILPNQDKSIFQKGSPCFDGEQPCQGKAEKLPNAIFCGKKSGRAPRDNERDIRACPTRPSVKTLIETFSPTESLRMPRNCRNLGSSPCLRKWGVPAMPPRFPIYRGLAPLYSKPQISPAAGWRPSAPFPSLPLAEVSESEDISGDVEEDLENLPPPPLEVLMDKSFAALECPECSQPAGSSLEETLLPGLQEASHPKRTWVSPRLKASMSPMDLLPSKGSGSSPRLHSTRSGSTRIVGDSRKLTLDLNSKQTASPSSEAKSRAQIQARAETIAGFSKQHQKAIPWHHTNPTPGQSRTLEPSLARFSRDPHSSEASRKGPERSLPRVRKASPQRAQWASQGDRRLQSLPSSHGPSQPGLPAVLSSPSPPLSPRTLSPPATRKTTSPPCQHPQSNPAPGSPPVRRTETNTPSSASCSSPSVSPSRGSKDSIHSEDSEATTAKASRNTCSIFYPAATSLFEAKSSSSTSHPQMLPEPGGLLRTPTGGWRGSSGQRLRADSQKRTVLNALNPLPFVRRTASDRQRQQGDQLQQSRSDWEFHSCQNSSSSSSSEENPKQELPPWNNSRVPELQGSSTKRASPLELCVLGHGLQPEARMNRGQDRPQPESQPQHKEIS
What is the function of this protein?
Plays an essential role for normal photoreceptor cell maintenance and vision.
What are the official names of this protein?
Photoreceptor cilium actin regulator.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Protein: EPL1_DEBHA
Sequence: MAIHPSKGTGGSKQSNSGARFRQRKISVKQPLTIYKQSDLPTLNASNDLEPSQIHHLNSNANQQQRDIHAIETGVDKNEEDEVHLQQVINAAQKVLLGSQNEDGDKKKDDSDKKTDASVYIPTPDASRIWTDASKYYNDKSFREPETYIKFSATVEDTVGVEFNMDEIDEEFLKNKLWKNYPKVKSPKVKSEKLDDTNKENDNARKCSEVEFEIICDKLEKIIEEKQPFLSMDPSNILSFKELSAYIIEEFNNSNKDKPYVQLGSNLKYISTTALKEKLSKELSFEPFVTLFDKSLLDQTSTNIVRPIPKLLELFGEPVYEHWKYRKIERKGKQIHPALKFEDPSANEKDNDNDPYICFRRREFRQARKTRRADTLGAERIRLLQKSMHRARDLVMSVCRRELIKLENWETDHAIFKLRSDAKNLKRVVGVKGDDFLFYPHKRKKIIKVKEEDEDKESSKIKRDKRSRFDSSREGSATSMPGSATIGTNAINKDRLANGQVHHTQEASSSSQPYVKLPPSKIPDMGLVTVSLVLKEKNETIKRAVLEKLRKRKEQDKDFINVTDDPYQPFFNIATNTKFKNNELKHIPYSSIAATSFHEINTTNYISEKLKNLLEEGKKPLPGTKTFRGSNGELIPSKPFPHLSALIQDRIDNSQFNSVSYIAQLLSNIENNNFSAYNNGYGQQQQHQHQETNRDKTKLSDPIFRLRKRVGRFNRNFVDRRGLMKRPNDVIDDFLKFDDEGVNDDCDQMDVDSESISKNNVPNVYDSRVDEIKRLDSRWQFDNDLTEYDKGLQSPFSLDPSRLNCISDDTQSIRFGSMLLSKSYDLLRDSVHQRQQALVQQARMRTLQQQQRNNKQQAAGQSSGSSSASLGSNTNSNSSISGQADQGQTNLTNSGITRQGGANVNGSQTSTTNNTRSSVSGGSMNPKLPTQSSQRSNTNSPLLASQPQGYSQQQKFNKIPPTSQSQSQSPTHAAGQLQTSKMYNKHGSNITPSNLKGPKFTPANNNQIGGSLPNRK
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
What are the official names of this protein?
Enhancer of polycomb-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the enhancer of polycomb family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LYSZ_PYRNV
Sequence: MIVVKIGGSVVCKDPTKVVENLPNYADKAVVVHGGGCLVNDLLKRMGVEPKFLTHPGGLVSRYTDLETLKVFVMAMSWINKSIVASLHALGVEALGLTGADLGVVKARRKEKVLVVDERGRQRVVDGGYVGRVVDIAVDKLRPPPLKVLSPVAVSERGELLNIDGDQLAFDVAKRLGAERLVLLSDVDGLIIGGSVVPRLTAAQAEELVKNEEVRGGMKRKLLMAAEAAKLGLEVVISNGLVDKPIDAALSGRGTHVVKG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
Putative [LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNN4_RAT
Sequence: MGGELVTGLGALRRRKRLLEQEKRVAGWALVLAGTGIGLMVLHAEMLWFLGCKWVLYLLLVKCLITLSTAFLLCLIVVFHAKEVQLFMTDNGLRDWRVALTRRQVAQILLELLVCGVHPVPLRSPHCTLAGEATDSQAWPGFLGEGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTLWLIPITFLTIGYGDVVPGTLWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIHYAKEMKESAARLLQEAWMYYKHTRRKDSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSMVDISKMHMILCDLQLGLSASHLALEKRIDGLAGKLDALTELLSTALQQQQPPEPIQEAT
What is the function of this protein?
Forms a voltage-independent potassium channel that is activated by intracellular calcium.  Activation is followed by membrane hyperpolarization which promotes calcium influx.  Required for maximal calcium influx and proliferation during the reactivation of naive T-cells.  The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
What are the official names of this protein?
Intermediate conductance calcium-activated potassium channel protein 4, SK4, SKCa 4, SKCa4, IK1, KCa3.1, KCa4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa3.1/KCNN4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2097_YERPB
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YPTS_2097.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHI1_APHAL
Sequence: MLSFVKKSIALVAALQAVTALATPISSEAGVEKRGSGFANAVYFTNWGIYGRNFQPADLPASEITHVLYSFMNVRADGTIFSGDTYADYEKHYAGDSWNDVGTNAYGCVKQLYLLKKQNRNMKVMLSIGGWTWSTNFPAAASSAATRKTFAQSAVGFMKDWGFDGIDIDWEYPADATQAQNMVLLLQAVRSELDSYAAQYAKGHHFLLSIAAPAGPDNYNKLKFAELGKVLDYINLMAYDYAGSWSNYTGHDANIYANPQNPNATPYNTDDAVQAYINGGVPANKIVLGMPIYGRSFQQTEGIGKPYNGIGSGSWENGIWDYKALPKAGATVKCDDTAKGCYSYDPSTKELISFDTPAMISTKVSWLKGKGLGGTMFWEASASKKGSDSLISTSHQGLGSQDSTQNYLDYPNSKYDNIKKGMN
What are the official names of this protein?
Chitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APCB_AROAE
Sequence: MYERIRFTEYLDLDLNDEHWYCHDCGTKLISARESYKKGCLVAERRPHEIHNPVIEGEYSFAPDENWVRILEFYCPGCTRQIETEYLPPGHPITVDIEVDIDSLKARLKKGVIVIKDGKLTKPEAEVLA
What is the function of this protein?
Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene.  Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
What are the official names of this protein?
Acetophenone carboxylase beta subunit, Acetophenone carboxylase 15 kDa subunit.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CAMC5
Sequence: MDISVFSIQKSRADSFENEIKEYIKMSAKFANISDKIIFNDKIAKAQSIGKDEALKAYDEAYEPNLKGFCVMLDERGSELNSSEFAKIFEQNMQLSFFIGGAYGLSKNLKDKAQKVISLSKMTMAHKIAKLVLFEQIFRGLCINANHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_VIBVY
Sequence: MKNAVHFGAGNIGRGFIGKLLADANVSVTFADVDAPLVDQLSHRQEYKVKVVGSECQIDTVTHVTAVNSASEEVIDRIVQTDLVTTAVGPNVLDIIAKTIAQGIAKRFAAGNLAPLNIIACENMVRGTTHLKGEVYKHLDASLHAQVDELVGFVDSAVDRIVPPAEAANDDPLEVTVESFSEWIVDEQQFKGEVPSIAGMEKTHNLMAFVERKLFTLNTGHCITAYLGCLQGHRTIREAIENPAICDQVKQAMMESGEVLIRRYGFDREMHQAYIEKILARFANPFLVDEVDRVGRQPIRKLGMNDRLIKPLLGTIEFGTANQHLLKGIAAALKYQNDSDPQAVELQRSLQQVGVKKTLAKYTSLAEDSVEVAKIETLYNQL
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: H2AZ_YEAST
Sequence: MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVEKKGSKK
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received (PubMed:11000274, PubMed:11081628, PubMed:11090616, PubMed:11509669, PubMed:12628191, PubMed:14645854, PubMed:14690608, PubMed:15045029, PubMed:16239142, PubMed:16344463, PubMed:16543223).  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins (PubMed:16543222).  Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes (PubMed:11509669).  Involved in chromosome stability (PubMed:15353583).  Required to target MPS3 to the inner membrane of the nuclear envelope (PubMed:21518795).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
Protein: YJNA_SCHPO
Sequence: MNPTTKRAIKEIVVYALAFGCSWYAAHKLLSTLDPYRQKRQDTVSKSRKRLDEWAGEQVKELETLELNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRELFDKHGNDLEAIKYDIQSGGLRSLKTEDFYHYESLQNVSGIDVE
What are the official names of this protein?
Uncharacterized AAA domain-containing protein C24B10.10c.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISPF_CORU7
Sequence: MTQPIIPRVGIASDAHQVEPGKPCWMAGLLFEDADGCEGHSDGDVVSHVIVDALLSASGLGDLGSFVGVGRKEYDGVSGERLITECRQLLAENGFTIGNVAAQMIGNRPKMGPRREEAERRLTELVGAPVSVSATTTDKMGFTGRGEGVAALATAVVWKAGA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PELD_PECCA
Sequence: MAYPTTNLTGLIGFAKAAKVTGGTGGKVVTVNSLADFKSAVSGSAKTIVVLGSSLKTSALTKVVFGSNKTIVGSFGGANVLTNIHLRAESNSSNVIFQNLVFKHDVAIKDNDDIQLYLNYGKGYWVDHCSWPGHTWSDNDGSLDKLIYIGEKADYITISNCLFSNHKYGCIFGHPADDNNSAYNGYPRLTICHNYYENIQVRAPGLMRYGYFHVFNNYVNKFQLAFTVAQNANVISERNVFGSGAEKKGMVDDKGNGSTFTDNGSSPAAVASKSPAAKWTASSNYSYSLMTTAAAQSWVVSNAGAQNSALKFPS
What are the official names of this protein?
Pectin lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.