PharMolix/UniProtQA huggingface dataset:
Protein: RS3A_ASPFC
Sequence: MAVGKNKRLSKGKKGVKKRTVDPFSRKDEYSVKAPSTFQIRDVGKTLVNRTSGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTTDKLRSLVRKWQSLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKMIEIMQREAASCSLAQLTHKLIPEVIGREIEKATQGIYPLQNVHIRKVKLLKAPKFDLGALLNLHGESTTDDKGHKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP45_KLULA
Sequence: MSFRTLSSLLPSPQNSEVSESSAFSRQSKENIKDTIILDKLRPENLPVASISDFVPLRQRDISLEAPFPSTSQINQTYVKTKAFLDSLLTKKSSLQLSSIANKDIVKREAISSVKSGTQRSVKVIEHKKDPLQPVTHRKRKVVVPSEEIQAPILHKSDDPSIKPTKEELDKWRIPSAISNWKNPNGFAISLDNRVAIESIKTDCPDNDKKDNFLLLSEALDEAEREARQRINIKQEAYKELEKEETLKKEQRLRHLAERARQDRENRRQYENEDHYVREMERNQRRRAERELERSNKMSTAEKLRRLAYQQGRDVSDKVVLNAAKATETPDLQYDSRLFKKAASSVASSSNQIFDHPLFNNSQIDNIYRPTTGSNLENEDIVDRLSNKKGRTGPVEFSAADDGKNAEQNEEDNEHAREYGLQVRKKPHTS
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing protein 45.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLIN_ASPFU
Sequence: MTVLPDSENGYLLNYEDQEKRRMNMQHDLIKTYMGKLILAPLPFDQPNLRVLDSGTFNGLWLEDASTLLQSPTLVGTDVSPTAFPAKRPPNTEFHVQSISDPWPTEWRDSFDLVHQKLVIACVPPDEGRQALYRLIDLAKPGTGWVQFTEGSLEHLTPEQRKQYPVLARFQSLVAEMLPHFRWNPRPGKLVRQWLEEYGLQEVQEKVMEIPIGAGNPDPKLGEMAKQNMLEVVSNFRTAATRLPDGTGIRAEDFDPILRDIKVEFETVGGILRFNTVWGRRP
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of gliotoxin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide bridged cyclic dipeptide (PubMed:15979823, PubMed:21612254).  The first step in gliotoxin biosynthesis is the condensation of serine and phenylalanine to form the cyclo-L-phenylalanyl-L-serine diketopiperazine (DKP) by the NRPS gliP (PubMed:17154540, PubMed:21612254).  GliP is also able to produce the DKP cyclo-L-tryptophanyl-L-serine, suggesting that the substrate specificity of the first adenylation (A) domain in gliP is sufficiently relaxed to accommodate both L-Phe and L-Trp (PubMed:23434416).  The cytochrome P450 monooxygenase gliC has been shown to catalyze the subsequent hydroxylation of the alpha-carbon of L-Phe in cyclo-L-phenylalanyl-L-serine whereas the second cytochrome P450 enzyme, gliF, is presumably involved in the modification of the DKP side chain (PubMed:24039048, PubMed:23434416).  The glutathione S-transferase (GST) gliG then forms a bis-glutathionylated biosynthetic intermediate which is responsible for the sulfurization of gliotoxin (PubMed:21513890, PubMed:21749092).  This bis-glutathionylated intermediate is subsequently processed by the gamma-glutamyl cyclotransferase gliK to remove both gamma-glutamyl moieties (PubMed:22903976, PubMed:24039048).  Subsequent processing via gliI yields a biosynthetic intermediate, which is N-methylated via the N-methyltransferase gliN, before the gliotoxin oxidoreductase gliT-mediated disulfide bridge closure (PubMed:20548963, PubMed:22936680, PubMed:24039048, PubMed:25062268).  GliN-mediated amide methylation confers stability to ETP, damping the spontaneous formation of tri- and tetrasulfides (PubMed:25062268).  Intracellular dithiol gliotoxin oxidized by gliT is subsequently effluxed by gliA (PubMed:26150413).  Gliotoxin contributes to pathogenesis during invasive aspergillosis (PubMed:17601876, PubMed:18199036).  In macrophages and neutrophils, gliotoxin showed inhibition of various different cell functions including cytokine production, antigen presentation, phagocytosis, and production of reactive oxygen species (PubMed:17601876).
What are the official names of this protein?
N-methyltransferase gliN, Gliotoxin biosynthesis protein N.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: PCDBC_HUMAN
Sequence: MENGGAGTLQIRQVLLFFVLLGMSQAGSETGNFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLLREMLDREELCGSNEPCVLYFQVLMKNPTQFLQIELQVRDINDHSPVFLEKEMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKALDYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKILENSILGSLVVTVSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDFEAIESYSIIIQATDGGGLFGKSTVRIQVMDVNDNAPEITVSSITSPIPENTPETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYALFVRENNSPALHIGSISATDRDSGTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQFRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCVTGGSRSNKFKFLKPIIPNFLPQSTGSEVEENPPFQNNLGF
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-12, PCDH-beta-12.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CCL7_MOUSE
Sequence: MRISATLLCLLLIAAAFSIQVWAQPDGPNASTCCYVKKQKIPKRNLKSYRRITSSRCPWEAVIFKTKKGMEVCAEAHQKWVEEAIAYLDMKTPTPKP
What is the function of this protein?
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils.  Augments monocyte anti-tumor activity (By similarity).
What are the official names of this protein?
C-C motif chemokine 7, Intercrine/chemokine MARC, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, Protein FIC, Small-inducible cytokine A7.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_AGRRK
Sequence: MSQSVSLTFPDGSVRSYDAGATGRDVAESISKSLAKKAVAIAIDGTVRDLSEPVADGKIEIITRNDDRALELIRHDAAHVMAEAVQELWPGTQVTIGPVIENGFYYDFAKNEPFTPDDLPVIEKKMREIIQRNKPFTRQIWSREKAKQVFADKGERYKVELVDAIPEGQDLKIYYQGDWFDLCRGPHMASTGQIGTAFKLMKVAGAYWRGDSNNPMLTRIYGTAFAEQADLDNYLHILAEAEKRDHRRLGREMDLFHFQEEGPGVVFWHGKGWRIFQTLVSYMRRRLEGDYQEVNAPQVLDKSLWETSGHWGWYRDNMFKVTVAGDDTDDDRVFALKPMNCPGHIQIFKHGLKSYRELPIRLAEFGNVHRYEPSGALHGLMRVRGFTQDDAHIFCTDEQMAAECLKINDLILSVYEDFGFEEVVVKLSTRPEKRVGDDALWDRAESVMMEVLKTIEAQSGGRIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIDQHSEKTQPVMIHRAICGSMERFLGILIENFAGHMPLWVSPLQVVVATITSEADGYGEEVAEALRDAGLTVETDFRNEKINYKIREHSVTKVPVIIVCGKKEAEERSVNIRRLGSQAQTAMSLDEAIASLSLEATPPDVLRKREAKRAKVA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEBP1_ARATH
Sequence: MATETEVVAPVTVSNGGSKGCCKYGGPGYATPLAAMSGPSEKLIYVTAVYTGTGIDKPDYLATVDVDPSSPSYSSVIHRLPMPFVGDELHHSGWNSCSSCHGDASVDRRYLVLPSLISGRIYAIDTKENPRAPSLYKYVDPKEIADKTGLAFPHTAHCLATGEILVSCLGDEEGNAKGNGFLLLDSDFNIKNRWEKPGHSPLYGYDFWYQPRHKTMISTSWGAPKAFSKGFNLQHVADGLYGSHLHVYSWPGGEIKQLIDLGPTGLLPLEIRFLHDPSKDTGFVGSALSSNMIRFFKNSDETWSHEVVISVKPLKVENWILPEMPGLITDFLISLDDRFIYFVNWLHGDIRQYNIEDPKNPVLTGQIWVGGLLQKGSPVKAVGEDGNTFQFEVPQIKGKSLRGGPQMIQLSLDGKRLYATNSLFSAWDRQFYPEIMEKGSHIIQIDVDTEKGGLTINPDFFVDFGDEPDGPSLAHEMRYPGGDCTSDIWI
What is the function of this protein?
Binds cadmium and mediates lower sensitivity to stress requiring glutathione (GSH) for tolerance (e. g.  cadmium, selenate, and hydrogen peroxide excess).  Probably helps to detoxify cadmium potentially through direct binding (PubMed:18354042, PubMed:19710230).  Binds selenium, cadmium, zinc and nickel in vitro (PubMed:25274629).
What are the official names of this protein?
Selenium-binding protein 1, AtSBP1.
What is the protein family that this protein belongs to?
Belongs to the selenium-binding protein family.
Protein: NSRR_ESCF3
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLMELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: MFH2_SCHPO
Sequence: MIVLRDSSDYSDSEVDLPSIEVNGERGNVPTSVLCNVEGSLLNSNPALRQPNLKCIKHNQDVENTTFQLDLRGCRVPSSQPQVITELENNIDIPKNIDAMQNWIFPQTQQYRNYQKEFCEQALFHNLLLALPTGLGKTFIAAVVMLNYFRWFPESKIIFLAPTKPLLLQQRVACSNVAGMSPGATAELNGEVSPDRRLFEYNTKRVFFMTPQTLQNDLKEHLLDAKSIICLIFDEAHRATGNHSYAQVMRAVLRSNSHFRVLGLTATPGSSTASVQKVVDCLHISKLIVRNEESIDIRSYVFHKKIQLIKVTISSEMNILKSDFANLYRPYFNFLRQKKLIPINCECLNIKAYTLFVSLRKYSFSSKNVQSKEKSKIMSCFTLLISCAHITYLLDCHGIIQFYQKLVETKNKAEGKGSGQSFWLFTSKPFAFYLEHLHNKIQGLSLNHPKMNHLLELLKEHFKDTSEGYQNQRVMIFTEFRNTAEYITTTLLAIRPMVRASLFIGQANSAYSTGMNQMQQKETIDQFRAGVINTLVATSIGEEGLDIGDTDMIICYDASSSPIRTIQRMGRTGRKKSGKVFVLLTEDCEDSKWERSQVSYRRVQKVIESGKKIALKKDVPRLIPSNIQPIFKFQALQNNADATLILNSYNNNSSSLSPVNTLANQAHSRSKRYLPFIVDDVFEDMESNLRVPTEDAKIKRFKSDYRSCIYNARRNVFSKPTYMGDKLTKFAKVPHSLLTLSIYRRGRLLQQCSPSSVTKYLKYEEKFKRKRMKKTSNALFQST
What are the official names of this protein?
Putative ATP-dependent DNA helicase fml2, FANCM-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
Protein: RSGA_FLAPJ
Sequence: MTGIVYKSTGSWYTVKSLQGHFMECRIKGKFRMKGIKSTNPIAVGDVVDYDLDENSDVVTGTITKIHDRKNYIVRKSVNLSHQMHIIASNLDYVFLLITINNPPTTTNFIDRFLVTAQAYGIETILVFNKIDTYNEAMLDEQLFMQYIYQEIGYKCLRVSSTEGKGIEELKNIMKNKVTMFSGHSGVGKSTLVNAMEPTLHLKTKTISEQSKQGQHTTTFAEMYDLSFGAQIIDTPGIKGFGIVDMEKEEISGYFPEFFKLKDQCKFNNCLHKDEPKCAVKDALEKDKISYSRYNSYLKILEGDDETYRTDIYNDDRIASDETRNK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_LACH4
Sequence: MAILEQPYLDLLQKIMSEGHGKDDRTGTGTRSYFGAQMRFDLSQGFPLLTTKKVPFGLIKSELLWFLRGDTNIRFLLEHNNHIWDEWAFKNWVNSSEYQGPDMTDFGLRSQSDPEFNKIYQAEMKKFDQRILDDEDFAKKYGNLGDVYGAQWRHWEKREGGFIDQIADVIKQIKETPDSRRMIVTAWNPEDVPTSALPPCHVMFQFYVVDGKISVQLYQRSGDMFLGVPFNIASYSLLLNLIARETGLQVGEFIHTLGDAHIYRNHLKQVEELLSRKPYDSPQLWLNPEKKNIADFEMKDIKVVDYQHHGTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS1_PSEAE
Sequence: MSESFAELFEESLKSLDMQPGAIITGIVVDIDGDWVTVHAGLKSEGVIPVEQFYNEQGELTIKVGDEVHVALDAVEDGFGETKLSREKAKRAESWIVLEAAFAADEVVKGVINGKVKGGFTVDVNGIRAFLPGSLVDVRPVRDTTHLEGKELEFKVIKLDQKRNNVVVSRRSVLEAENSAEREALLESLQEGQQVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRIKHPSEIVNVGDEIDVKVLKFDRERNRVSLGLKQLGEDPWVAIKARYPEGTRVMARVTNLTDYGCFAELEEGVEGLVHVSEMDWTNKNIHPSKVVQVGDEVEVQVLDIDEERRRISLGIKQCKSNPWEDFSSQFNKGDRISGTIKSITDFGIFIGLDGGIDGLVHLSDISWNEVGEEAVRRFKKGDELETVILSVDPERERISLGIKQLEDDPFSNYASLHEKGSIVRGTVKEVDAKGAVISLGDDIEGILKASEISRDRVEDARNVLKEGEEVEAKIISIDRKSRVISLSVKSKDVDDEKDAMKELRKQEVESAGPTTIGDLIRAQMENQG
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: RS19_BACC1
Sequence: MARSLKKGPFVDDHLMSKIAKLNETEQKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHDADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ORR7_ORYSI
Sequence: MRVPAAVTGGCGCGVDGGGGCCRGGGKLADWEEGKDDEMKSVVVKGWTRMAQVVPLHDNASAEDDDDDEEDDDEDDDDDDDEDDEEEAAPPYVMAVDDSSVDRAVITALLRRSKYRDSGKRALEILGSEPNVSMIITDYWMPEMTGYDLLKKIKESSELKQIPVVIMSSENVPTRISRCLEEGAEDFLLKPVRPADISRITSRMLQ
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR7, Type A response regulator 7, OsRR7.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
Protein: TRMA_SALCH
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: MAOM_YEAST
Sequence: MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTRSHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPVDGYRISENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGGAPGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL
What are the official names of this protein?
NAD-dependent malic enzyme, mitochondrial, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YDFE_SCHPO
Sequence: MSNPTIEGDENRKENTKSNTKPNFDDLDDLDDILDDLDVPSAFKNEEKKNIDEHKQTGNTSKENERIKNDDNLNSLIQEMMSKFEDLGGPSGLDGSQLSSSFQNDQLLNVILEDQFATEKDSDNGAVNYGALEAALNSLMSQVTSKEILYEPLKDLEANYPKFLKNAKETEKQGFEEQYQKIQKCIQIFESPEYDARKDADIISKLVEEIQEKPLPAPLIDNSMETAGCPTQ
What are the official names of this protein?
Uncharacterized protein C17C9.14.
Protein: PSAA_MARPO
Sequence: MTIRSPEPEVKIVVEKDPVKTSFEKWAKPGHFSRTLAKGPSTTTWIWNLHADAHDFDSHTNDLEEISRKVFSAHFGQLAIIFIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQLWRASGITSELQLYSTAIGGLVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQLLDAGVDPKEIPLPHEFILNRDLLAELYPSFAKGLTPFFTLNWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAVLFLVAGHMYRTNWGIGHSFKEILEAHKGPFTGEGHKGLYEILTTSWHAQLALNLAMLGSLTIIVAHHMYAMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTQYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPNFTAPNALASTSLTWGGGDVIAVGSKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTISEQGVVTHITGGNFAQSAITINGWLRDFLWAQASQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSITQGRAVGVAHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PELO_THEKO
Sequence: MQILEEKPKEGKVKVKAETLDDLWHLYHIIDPGDIVYAKTLRKQAQRADSLRAEKVEVIPVFLGVQAEKINFHKFANQVRVTGPIVYASREDVPLGKYHTIAIEQGTVVTIQKPRWKEHHIERLKEAVAASKRARVMIVVIDDGEADMALVREYGVEILNSIRHNLGGKRYNTDRESEEMKFFHDVAKTMEEVMKRENVEKAIVAGPGFVKEDFYKFLKEKYPELAKKVVIEDTSVTGRTGIYEVIKRGVVDRVYQENRVAKEVQLVEKVLENIARNNGLVAYGLKEVEEAVNYGAVETLLVLDELLKGELREKVEELMDAVRYSRGEVVVVSSEHEGGEKLKALGGLAALLRFRVK
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB5_BRUSU
Sequence: MKKIILSFAFALTVTSTAHAQLPVTDAGSIAQNLANHLEQMVKFAQQIEQLKQQFEEQKMQFDALTGYRGLGDILRDPTLRSYLPHNWRDLYEAVMSGGYLAAAGETANLLRKSQVYDPCASISDKDQRIACEAKVVKPVQDKVMTSKAYDATDKRLQEIESLMQEINKTGDPKAIAELQGRIESENAMIQNEDTRLHLYQQMAEAQDKLLDERQHELDAKDNARRGYPQPKALEAAY
What is the function of this protein?
The VirB system could be required for the establishment of the replication niche in the host.
What are the official names of this protein?
Type IV secretion system protein virB5.
What is the protein family that this protein belongs to?
Belongs to the virb5 family.
Protein: MKRN1_DANRE
Sequence: MAEAAAASTAAPAVIGGWTKHVTCRYFMHGLCKEGENCRYSHDLSSCKQTMICKFFQKGCCAFGDRCRYEHTKPSKQDEVPSSKPSMPLTAAPLAGTPEPVSDGPGGTTGAQEKPQGSGAVDWVNAAEFVPGQPYCGRADPVLCEGPGPLIEEEYEKEQANKEMKKQLCPYAAVGECRYGLNCAYLHGDVCDMCGLQVLHPSDTSQRSQHIRACIEAHEKDMEISFAIQRSKDMMCGVCMEVVFEKTNPSERRFGILSNCCHCYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEDKEEKQQLIQKYKDGMGTKPCRYFDEGRGTCPFGANCFYKHAFPDGRLEEPQPQRRQNGSNGRNRNTRRTHLWDLLDERENSDSFDNEDEEMVRFELSEMLLMLLAAGTDDDVTDSEDEWDLFHEELDDYYELYL
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase makorin-1, RING-type E3 ubiquitin transferase makorin-1.
Protein: RL7_ACTPJ
Sequence: MSLTNEQLIEAIASKSVSEIVELIAAMEEKFGVSAAAAVAAAPAAGAAAAEEKTEFDVILAEAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGISKPEAEALKKELEEAGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CQSS_VIBC1
Sequence: MDAIRKVYQYAEPNLSLVGWMGFIGFPIYYIVWEFMFPQPYENLPLRILCSVLFFGIIYRNRTPFEWRGFLPAYYQVVTTLCLPCFFFYMLLMNNWSNVWVMSFMSAIFLHILLVHITSVMFVQTFVGIGLATFFAWVAQGFHLELTMDWTHVPIFLFIYLFGNLFYFRNQVEHEAKVSIAKSFGAGIAHEMRNPLSGLLTSIDVIQSVLPNPKEGKKEQYTLSDEDVTLLREVSSDAMKIIHSGNETIDLLLTSIDENRVSRSTFKKHSAQSVVESAIESFSYKRSTDRFAISLDVRSEFDFLGSDTLLKYVMYNLFKNAFHHRSSEDFHIHVTMYSDEFANQIVVTDNGSGIAPEVLQSIFQDFYTTGKSGNYGLGLPFCKKVMRSFGGDIRCQSEVGEWSQFTMTFPTIGSSAVKEIKSELTKLKTILFVSEQNILVSKVTDIARFMRFELTVLDVPAVLKNKEYEFEFDLILIDMESLDASGSHIDKVESLLSFTEARIVYMFEHHPIQRARSVSFEPIWVETQAWLLNTRATIDRLLYDANYVVPSMPAKPLDSTNKRTIMVVDDNESLRKFTAMLLEKQGFEVIQTEDGLQAINALNENNVDLILMDIEMPVMDGVEASRQIRGSNKAYASVPIIAHTGDSSPITLDKIGSSGMSDFIVKPADKNRLFDKIANWI
What is the function of this protein?
Senses the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal.  The sensory signal is then relayed to LuxU and LuxO.
What are the official names of this protein?
CAI-1 autoinducer sensor kinase/phosphatase CqsS, Cholerae quorum-sensing sensor.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YSCB_YEREN
Sequence: MQNLLKNLATSLGRKPFVADKQGVYRLTIDKHLVMLTPHGSELVLRTPIDAPMLREGNNVNVTLLRSLMQQALAWAKRYPQTLVLDDCGQLVLEARLRLQELDTHGLQEVINKQLALLEHLIPQLTPFSVASRVGWN
What is the function of this protein?
Functions as a specific chaperone for YopN.  It could facilitate the secretion and the subsequent translocation of YopN.
What are the official names of this protein?
Chaperone protein YscB, Yop proteins translocation protein B.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein. Note=Not exported across the inner membrane.
Protein: SDF2A_DROER
Sequence: MLRQLRLTMDISGWIFLPWRRSMSNMKESPPPPPLASTFDDVIVDYEDPDYLPLPEYPLRPNEPLQTRKQRLLYQSRKRGMLENDLLLSTFAAKHLQSFSAEQTAQYDQLINGVSNDWDIYYWATDVKPTPKEYDTEIMGLLKEHVKNAERVSRLRQPDLNT
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-A, mitochondrial, SDH assembly factor 2-A, SDHAF2-A.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS4_RALSO
Sequence: MARYTGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGNQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGENLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKAILVNGQALNVPSAQIKSGDVVAIREKSKKQVRIAESLSLAEQTGFPGWVAVDAKKMEGTFKQAPDRGDIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.