PharMolix/UniProtQA huggingface dataset:
Protein: PEX7_HUMAN
Sequence: MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA
What is the function of this protein?
Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal (PubMed:9090381, PubMed:11931631, PubMed:22057399, PubMed:25538232).  Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol (PubMed:11931631, PubMed:22057399, PubMed:25538232).  Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:11546814, PubMed:25538232).
What are the official names of this protein?
Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat peroxin-7 family.
What are the subcellular locations of this protein?
Peroxisome. Cytoplasm.
Protein: RLP34_ARATH
Sequence: MKGSWVVSTSIIRITLSFTFLFICHFSDVLAAPTRHLCRPEQKDALLKFKNEFEIGKPSPTCKMVGIESHRKTESWGNNSDCCNWEGVTCNAKSGEVIELNLSCSSLHGRFHSNSSIRNLHFLTTLDRSHNDFEGQITSSIENLSHLTSLDLSYNRFSGQILNSIGNLSRLTSLDLSFNQFSGQIPSSIGNLSHLTFLGLSGNRFFGQIPSSIGNLSHLTFLGLSGNRFFGQFPSSIGGLSNLTNLHLSYNKYSGQIPSSIGNLSQLIVLYLSVNNFYGEIPSSFGNLNQLTRLDVSFNKLGGNFPNVLLNLTGLSVVSLSNNKFTGTLPPNITSLSNLMAFYASDNAFTGTFPSFLFIIPSLTYLGLSGNQLKGTLEFGNISSPSNLQYLNIGSNNFIGPIPSSISKLINLQELGISHLNTQCRPVDFSIFSHLKSLDDLRLSYLTTTTIDLNDILPYFKTLRSLDLSGNLVSATNKSSVSSDPPSQSIQSLYLSGCGITDFPEILRTQHELGFLDVSNNKIKGQVPGWLWTLPNLFYLNLSNNTFIGFQRPTKPEPSMAYLLGSNNNFTGKIPSFICELRSLYTLDLSDNNFSGSIPRCMENLKSNLSELNLRQNNLSGGFPEHIFESLRSLDVGHNQLVGKLPRSLRFFSNLEVLNVESNRINDMFPFWLSSLQKLQVLVLRSNAFHGPINQALFPKLRIIDISHNHFNGSLPTEYFVEWSRMSSLGTYEDGSNVNYLGSGYYQDSMVLMNKGVESELVRILTIYTAVDFSGNKFEGEIPKSIGLLKELHVLNLSNNAFTGHIPSSIGNLTALESLDVSQNKLYGEIPQEIGNLSLLSYMNFSHNQLTGLVPGGQQFLTQRCSSFEGNLGLFGSSLEEVCRDIHTPASHQQFETPQTEEEDEDLISWIAAAIGFGPGIAFGLMFGYILVSYKPEWFMNPFGRNNRRRKRHTTTH
What are the official names of this protein?
Receptor-like protein 34, AtRLP34.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LUXS_LIGS1
Sequence: MAKVESFTLDHTAVKAPYVRLITVETGAKGDKISNFDLRFVQPNENAIPTAGLHTIEHMLAGYLRDHMDGVIDCSPFGCRTGFHLIMWGEHDTTEVATALKASLNDIINASWEDVQGTDIKSCGNYRDHSLFSAQEWCKKILADGISTDPFERKVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: ROCR_BACSU
Sequence: MVKDSEFLTLVFQSILDEIDVGLHVVDEHGNTIVYNNKMMQIEDMEKHDVLNKNLMDVFMFSKQQDSTLVQALQEGKTIKNVKQSYFNNKGQEITTINHTYPIVQDGKIRGAVEIAKDVTKLERLIRENMNKKGSTTYTFDSILGTSPAIQDVIENAKRATRTSSSVLLAGETGTGKELFAQSIHNGSDRSGGPFISQNCAALPDSLVESILFGTKKGAFTGAVDQPGLFEQAHGGTLLLDEINSLNLSLQAKLLRALQERKIRRIGSTKDTPIDVRIIATMNEDPIDAIAGERMRKDLYYRLSVVTLIIPPLRERKEDILLLASEFIQKNNHLFQMNVEHISDDVKQFFLSYDWPGNIRELEHMIEGAMNFMTDEQTITASHLPYQYRMKIKPADIPEPETPRHQPAADLKEKMESFEKYVIENVLRKHGHNISKAAQELGISRQSLQYRLKKFSHSSNE
What is the function of this protein?
Positive regulator of arginine catabolism.  Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences.
What are the official names of this protein?
Transcriptional activator RocR, Arginine utilization regulatory protein RocR.
Protein: ATPL_GLAP5
Sequence: METVITATIIGASILLAFAALGTAIGFAILGGKFLESSARQPELASSLQTKMFIVAGLLDAIAMIAVGISLLFIFANPFIDLLK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_VIBA3
Sequence: MIALIQRVSEAAVRVDGEVVGEIEQGLLVLLGVEKGDDEAKAKRLMERVTTYRVFGDEDDKMNLNVKQVEGKVLVVSQFTLPADTKKGTRAGFSRGAHPEDAERLYNYFSDQCESVLPTERGRFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_CLOBK
Sequence: MYEYLDRRYALALYEVAEENNKVDEYLRDLKEVVNIIKNSEDICKILKHPEINTSRKKEIFTELFKDKVDDKILSFLLVLIEKDRILYLEEKLKEMEKIYLEKNNMILANVKTVIPLLKEEREELIEKLGNKYNKKIILEEEIDKSIIGGVYVRVGDDVLDGTLSTRLKDIKKMMLKRE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BPTA_BORAF
Sequence: MSRILFYGLLLICIFLGFFFYKQKENNIIYNRIVEKFEDNVVIDEIYTHLFKDSNLKELVFIKSQLIIPELEHKKMIKATGYRADAYKALSTVYRFDFKVHDNKILGFKSVIFEGFEDAKVSKHENNLPSEKWQQLKDFNIGDPNINEKFFHLEFPFVVKNTLCVTISKGFFKKIKKLKRLKIMLISNEDREYKIDIENFLPKYNL
What is the function of this protein?
Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the Lyme disease spirochete.
What are the official names of this protein?
Protein BptA, Borrelial persistence in ticks protein A.
What is the protein family that this protein belongs to?
Belongs to the BptA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SYGB_PSEPF
Sequence: MSAQDFLVELGTEELPPKALNTLAEAFLAGIDKGLQAAGLNYESKTVYAAPRRLAVLITALATQQPDRSINLDGPPRQAAFDADGNPTQAALGFAKKCGVELSEIDQSGPKLRYSQNIAGKPTASLLPTIVEDSLNDLPIPKRMRWGARKEEFVRPTQWLVMLLGDQIIDCTILAQKAGRESRGHRFHHPQSVRIGSPSSYLADLRAAYVLADANERREIISKRTEELATRQEGTAIVPPALLDEVTALVEWPVPLVCSFEERFLDVPQEALITTMQDNQKYFCLLDADGKLLPRFITVANIESKDPQQIIAGNEKVVRPRLTDAEFFFKQDKKQKLEAFNDRLQNVVFQEKLGSVYDKAERVSKLAAYIAARIGGNASWAARAGLLSKCDLATEMVGEFPEMQGVAGYYYALNDGEPEDVALALNEQYMPRGAGAELPATLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLNDAVAFAVNAFGAKVKAAGLNDAVLEFIFDRLRARYEDEGVGVATYLSVRALKPGSALDFDQRVQAVQAFRKLPEAAALAAVNKRVSNLLSKVEGSVPTEVQAKYFDNANEFSLYSAIQQADQAVQPMAAARQYNESLARLAALREPVDAFFDAVMVNAEDANVRANRYALLARLRGLFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREF_SALG2
Sequence: MLNQKLNPTPSEDLTIDVDLLYETDPCELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDAGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHYLWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIMATEYETGEQWDKPNGWAPLQWMAIQGFKRYGDDMLGDEIAHNWLKTVNHFYQEHHKLIEKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRY6_CANAL
Sequence: MSLPSPPVLKTTIIQLNKELDPEDDNNNYEILTNDYNNYGSSNTSDAGSIPTSPIIEVSGTTKSGSGLPNKKKRRRSTANIDSEELAKRKNETKQLHSIIEKRRRIKINREFEALKYLIPACRNCNTGSSGGSATPTSSTKKASTNSNNNGNKIDGMYKLTILKSSVEYILYLHHIIQKQHQLLSSISAKDTNGGILAEKLKAFEDFDIDFAKVPLNVNQYRNIDKDFNFKDLMQDLDGRSVNTESPETIIEENEPVSETSSTNNTTTLHYSNSSVLPSRTSSIVSSRQSSSLPTPELTPILSILNKYSTSNNQLNNRKNSNPISPQTVCIKSQNPSPFTMPMKSSLSTSIVNSPSSSSSLSGSKSYMAGNNAVNTVKFSLPDPVVNPNSTLNDNIPRKGLISGIPEEEEEEKINKGSANTETVNSGSASSDENNDNDRGVLLKLTDQDVSKTLLALRKSSIDSLLN
What is the function of this protein?
Transcription factor required for yeast cell adherence to silicone substrate.
What are the official names of this protein?
Transcriptional regulator of yeast form adherence 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1710_GLUOX
Sequence: MAETTRLLVDADACPVKDEIYRVGARYGLKTVIVANSWMNIPQSPLIERVVVPEGPDVADDWIAEQATPADIVITNDVPLAVRCLAKQTSVLRPNGEEIDERSVGMVSAMRDLMQGLRETGAVTTYNPSFGKADRSRFLSALDTLIVRLRRKAALARTVPSSSQTIHRPVPGDVP
What are the official names of this protein?
UPF0178 protein GOX1710.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: KCY_COXBU
Sequence: MNARQKPAPVITIDGPSGSGKGTIAFRIAQTLNWYLLDSGIIYRAIAWAMAHYKVPLEDSAGLARLLKRVQISIENRILGKKAKISCDGHDITLAIRSEECGALASRASALPIVREAVLQYQRDFRQRPGLVADGRDMGTVVFPDAVLKFYFDADSQQRAYRRYKELQDRGINVSLPDIQEDLEERDRRDITRSISPTKPAEDAVIIDTTHLSIEAVFATVMNHVRQRGLANVANEK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y586_HAEIN
Sequence: MELFKSIVAVIGIIATIYFLIKKAETRTVLIGVGLIMSILTLNPMGALDAFAKSMTSGGLIMAICSSMGFAYVMKYTQCDTHLVHLLTKPLSGLKFFLIPIATIITFFINIAIPSAAGCAAAVGATLIPVLKSAGVRPATAGQLF
What are the official names of this protein?
Putative uncharacterized transporter HI_0586.
What is the protein family that this protein belongs to?
Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: P2F3S_XENLA
Sequence: MTREPDSTVEQQHGNGHLENGTEQDTLDFSRQIKTEDLSEALQTGIPHRPCQLSQASMMGGGQMTGDFTSLHPLQQLVLVPSHLQSASQYLLSQSQSGQQGLLQQNHLSLNQQQGGILQPQTGLGLASQAVGCPGLPGSSLESHLEMGHLHAPKHFSVVPEDPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESAPSDTALTPSTNYAQLSEMFGRKRKKRTSIETNIRLTLEKRFEDNPKPISEEISMIAEQLVMEKEVVRVWFCNRRQKEKRINCPMNIPLKSPVYNSRMVPTSVSLGSMSMTPVHNTMTSTVTSSCSPVSSSRPSSPTSGLEPSSPGSSLNSPKPTVNTSSYNNSSSWYRWNHSQYFH
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways.
What are the official names of this protein?
POU domain, class 2, transcription factor 3S.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
Protein: THYX_MYCVP
Sequence: MAEIAPLRVQLIAKTEFSAPPDVPWSTDADGGAALVEFAGRACYQSWDKPNPRTATNAGYVRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEHDSQVVAPPGIEDDPELLEIFTEAADAGRAAYTELLTRLEARLADQPNATLRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADLEIRRLAIECLRQLVDAAPQVFSDFEIVVLADGTEVATSPLATEV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: GATA_BURO1
Sequence: MHAKSLTELRAALAAKECSAVELAQHYLKRIDAARDLNAFVHVDADLTLAQAKAADAELARGAGGALTGLPIAHKDVFVTRGWRSTAGSKMLANYESPFDATVVARLQAAGMVTLGKTNMDEFAMGSSNENSAFGAVKNPWDTNAVPGGSSGGSSAAVAARLAPAATGTDTGGSIRQPASFAGVTGIKPTYGRVSRYGMIAFASSLDQGGPMAQSASDCALLLNAMAGFDERDSTSLERDDEDFTRHLGQPWAAGNDAGKPLAGLRIGLPNEYFGAGLADDVRATIDAALKQYEALGATLVPVSLPKTELSIPVYYVIAPAEASSNLSRFDGVRFGHRAAQYGDLLDMYKKSRAEGFGPEVKRRILVGTYVLSHGYYDAYYLQAQKIRRIIANDFQEAFKSCDVIMGPASPTVAWDLGAKGDDPVQMYLADIYTLSVSLAGLPGMSVPCGFGAGANAKRPVGLQIIGNYFNEARMLQVADAFQRATDWHKQVPAGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: KCNKI_HUMAN
Sequence: MEVSGHPQARRCCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKWCPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIYKNVMLFFAKGKFYHLVKK
What is the function of this protein?
Outward rectifying potassium channel.  Produces rapidly activating outward rectifier K(+) currents.  May function as background potassium channel that sets the resting membrane potential.  Channel activity is directly activated by calcium signal.  Activated by the G(q)-protein coupled receptor pathway.  The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation.  Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids.  Channel activity is also enhanced by volatile anesthetics, such as isoflurane.  Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper.  May be involved in the somatosensory function with special respect to pain sensation (By similarity).
What are the official names of this protein?
Potassium channel subfamily K member 18, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPH_SYNJA
Sequence: MSWQRPDGRTAAQLRPISFQRHFTRYAPGSVLVKFGDTHVLCTASVAEEVPPFLQNTGQGWLTAEYRMLPTATQQRQPRETLKVSGRTAEIQRLIGRSLRAALDFHKLGSRTITVDADVLQADGSTRTAAITGGYVALHDAITWLYKQGLLDPAQGSPLRQQVAALSVGIVRGEVLVDLCYEEDSQAEVDMNIVMNEQGALIEIQGTAEAGCFDRSQLLQMLDMAQAGIQELLRAQRETLNL
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ENOPH_MAGO7
Sequence: MASAVKVFLLDIEGTVCPISFVKDVLFPYALEALPHTLDSQWDDPAFAQYRDAFPAEYASSKEALAAHVRDLVSRDVKAPYLKSLQGYLWKNGYDSGEIRAPLFADVAPKFAAWQAAGIAIMIYSSGSVPAQKLLFGHTNSEPADLTSAIADFFDTVNAGPKTEIASYEKIASMHPQYPKNEWLFLSDNVKEVDAALGAGFQSFVVQRPGNPELPDGVEDRHKVIRSFEEL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAPSH_ADE41
Sequence: MATPSMMPQWSYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHDVTTDRSQRLTLRFVPVDREDTAYSYKVRFTLAVGDNRVLDMASTYFDIRGVLDRGPSFKPYSGTAYNSLAPKTAPNPCEWKDNNKIKVRGQAPFIGTNINKDNGIQIGTDTTNQPIYADKTYQPEPQVGQTQWNSEVGAAQKVAGRVLKDTTPMLPCYGSYAKPTNEKGGQASLITNGTDQTLTSDVNLQFFALPSTPNEPKAVLYAENVSIEAPDTHLVYKPDVAQGTISSADLLTQQAAPNRPNYIGFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLMLDALGDRSRYFSMWNQAVDSYDPDVRIIENHGVEDELPNYCFPLGGSAATDTYSGIKANGQTWTADDNYADRGAEIESGNIFAMEINLAANLWRSFLYSNVALYLPDSYKITPDNITLPENKNTYAYMNGRVAVPSALDTYVNIGARWSPDPMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRVDGASVRFDSINLYANFFPMAHNTASTLEAMLRNDTNDQSFNDYLCAANMLYPIPSNATSVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFTYSGSVPYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKRTVDGEGYNVAQCNMTKDWFLIQMLSHYNIGYQGFYVPESYKDRMYSFFRNFQPMSRQVVNTTTYKEYQNVTLPFQHNNSGFVGYMGPTMREGQAYPANYPYPLIGQTAVPSLTQKKFLCDRTMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRIHQPHRGVIEAVYLRTPFSAGNATT
What is the function of this protein?
Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid.  Assembled into trimeric units with the help of the chaperone shutoff protein.  Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid.  Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.
What are the official names of this protein?
Hexon protein, CP-H, Protein II.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Forms the capsid icosahedric shell. Present in 720 copies per virion, assembled in 240 trimers.
Protein: AMPA_HAEIN
Sequence: MKYQAKNTALSQATDCIVLGVYENNKFSKSFNEIDQLTQGYLNDLVKSGELTGKLAQTVLLRDLQGLSAKRLLIVGCGKKGELTERQYKQIIQAVLKTLKETNTREVISYLTEIELKDRDLYWNIRFAIETIEHTNYQFDHFKSQKAETSVLESFIFNTDCAQAQQAISHANAISSGIKAARDIANMPPNICNPAYLAEQAKNLAENSTALSLKVVDEEEMAKLGMNAYLAVSKGSENRAYMSVLTFNNAPDKNAKPIVLVGKGLTFDAGGISLKPAADMDEMKYDMCGAASVFGTMKTIAQLNLPLNVIGVLAGCENLPDGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDVATLTGACVVALGQHNSGLVSTDNNLANALLQAATETTDKAWRLPLSEEYQEQLKSPFADLANIGGRWGGAITAGAFLSNFTKKYRWAHLDIAGTAWLQGANKGATGRPVSLLTQFLINQVK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y463_STRPS
Sequence: MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVINGVFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGTLLLLAYAGTQTRAGSLKKD
What are the official names of this protein?
UPF0397 protein SPCG_0463.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RH41_ORYSJ
Sequence: MEQEENHSADHLSAQPGNGNELEESSVKERCFEQREALVGEPRCVICGRYGEYICDQTDDDICSVECKTILLSKLSAETRPVVKAAKRVNLPVGDESFCIRDENFPKIPSMHDGQIASLRSKLDICVKGEDVPDPIMCFSSSGLPEKLVLNLEAAGYVMPTPVQMQVIPSSICNRSLLVSADTGSGKTASFLVPIIAHCSHVRSERCTDKQGPLAIVLAPTRELCLQVEEQAKVLGKGLPFKTALVVGGDPLAQQIYRIENGIELIVGTPGRLIDLLMKHNVDLNKVDVFVLDEVDCLLERGFRDQVMQIFQALSHPQVMMFSATVNSEVEKMSNSLAKNAIHISCGNPSRPNKSVKQVVIWVESKQKKQKIFEIMTSKQHFKPPAVVFVSSRIGADLLSEAITVATGLKVVSIHGDKTMNERRESLRRFLTGEVSVVVCTGVLGRGMDLLKVRQVILFDMPNSIDEYVHQVGRASRMGVEGMAIVFVNEEDRNLFRELVQILKTAGAPIPRELANSKYTTGIPLGGGKKRKLKSR
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 41.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX59 subfamily.
Protein: UBIE_STRMK
Sequence: MSESPYKAGTTHFGFRDVAAKDKQKLVGQVFTSVARNYDLMNDLMSLGVHRAWKRYYVATAQVKPGDRVLDLAGGTGDIAALLKERVGAEGSVVLGDINAGMLSVGRDRLTNRGLVLGLDYVQCNAEALPFLDNSFDLVTIAFGLRNVTDKDAGLREMYRVLKVGGQARVLEFSEVTADWFKPIYDFHSFKILPKLGKLFANDSDSYQYLAESIRKHPPQDELKAMMGQAGFERCHYKNLTGGIVSIHSGYKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: COF2_XENLA
Sequence: MASGVTVNDEVIKVFNEMKVRKSSTPEEIKKRKKAVLFCLSPDKKEIIVEETKQILVGDIGEAVQDPYRTFVNLLPLDDCRYGLYDATYETKESKKEDLVFIFWAPDNAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRCTLADKLGGNVVVSLEGVPLK
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  It is the major component of intranuclear and cytoplasmic actin rods (By similarity).
What are the official names of this protein?
Cofilin-2.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton.