PharMolix/UniProtQA huggingface dataset:
Protein: PG141_VACCW
Sequence: MISNYEPLLLLVITCCVLLFNFTISSKTKIDIIFAVQTIVFIWFIFHFVHSAI
What is the function of this protein?
Protein probably involved in counteracting host defense, since it enhances virulence in vivo.
What are the official names of this protein?
Virion membrane protein OPG141.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG141 protein family.
Protein: SESN3_MOUSE
Sequence: MNRGGSSASASANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTADERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPDRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLRNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPGIANGFRLISVSSFCVCDLANDNSIENTSLAGSNFGIVDSLGELEALMERMKRLQEDREDDETTREEMTTRFEKEKKESLFVVPGETLHAFPHSDFEDDVIVTADVSRYIEDPSFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTTLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFTHSEKVHVNLLLMEARMQAELLYALRAITRHLT
What is the function of this protein?
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25259925).  May also regulate the insulin-receptor signaling pathway through activation of TORC2 (PubMed:25377878).  This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).  May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity).
What are the official names of this protein?
Sestrin-3.
What is the protein family that this protein belongs to?
Belongs to the sestrin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_PARL1
Sequence: MSSDGTPGRKRSAKVRSSVSGLEIEVLREAGDWESSTDETVRRAAEHAYAVARGDESAELCIVLGDDALVAKLNKAYRGKEGPTNVLSFPAAEMPDTGAPEAVFGGATPLLGDVVLARETIAREALDQNKKFADHLSHLTVHGVLHLLGHDHMEDVDADEMEALERDILEDLGIADPYGADHPGQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_AROAE
Sequence: MQPSALLLLGPTASGKTASALALARVLPIEIVSVDSALVYRDMDIGTAKPTAAERAACPHHLVDIVSPEESYSAAHFRRDALRLIGEIHARGRIPLLAGGTMLYFKALRDGLSDLPAADADLRADIDAAAARLGWPALHAQLAQIDPDAAARLDSADAQRIQRALEIVRLTGRPLAESYARREAAALPFRMLPIALVPSDRAVLHARIEQRFDQMLAAGLIDELRALRARYTLDATLPSMRCVGYRQVWEYLDGGDDYDTMRFKGIAATRQLAKRQLTWQRQFRDSWPGLVELDCLRPDLTNAVNTAAARLLTRSRHAAH
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: B3GL1_RAT
Sequence: MAPAVLTAIPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFQFTLREHSNCSQQNPFLVILVTSRPSDVKARQAIRVTWGEKKTWWGHEVLTFFLLGQEAEREDKVLALSLEDEHALYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIENYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPKIYEMMGHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLFRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
What is the function of this protein?
Transfers N-acetylgalactosamine onto globotriaosylceramide.  Plays a critical role in preimplantation stage embryonic development.
What are the official names of this protein?
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1, Beta-1,3-GalNAc-T1, Beta-1,3-galactosyltransferase 3, Beta-1,3-GalTase 3, Beta3Gal-T3, Beta3GalT3, b3Gal-T3, Beta-3-Gx-T3, Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, Globoside synthase, UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: XYND_ASPFN
Sequence: MPGAASIVAVLAALLPTALGQANQSYVDYNIEANPDLFSECLETGGTSFPDCESGPLSKTLVCDTSAKPHDRAAALVSLLTFEELVNNTANTGHGAPRIGLPAYQVWNEALHGVAHADFSDAGDFSWSTSFPQPISTMAALNRTLIHQIATIISTQGRAFMNAGRYGLDVYSPNINTFRHPVWGRGQETPGEDAYCLASTYAYEYITGIQGGVDANPLKLIATAKHYAGYDIENWDNHSRLGNDMQITQQDLAEYYTPQFLVASRDAKVHSVMCSYNAVNGVPSCSNSFFLQTLLRDTFDFVEDGYVSGDCGAVYNVFNPHGYATNESSAAADSIRAGTDIDCGVSYPRHFQESFHDQEVSRQDLERGVTRLYASLIRAGYFDGKTSPYRNITWSDVVSTNAQNLSYEAAAQSIVLLKNDGILPLTTSSSTKTIALIGPWANATTQMLGNYYGPAPYLISPLQAFQDSEYKITYTIGTNTTTDPDSTSQSTALTTAKEADLIIFAGGIDNTLETEAQDRSNITWPSNQLSLITKLADLGKPLIVLQMGGGQVDSSALKNNKNVNALIWGGYPGQSGGQALADIITGKRAPAARLVTTQYPAEYAEVFPAIDMNLRPNGSNPGQTYMWYTGTPVYEFGHGLFYTNFTASASAGSGTKNRTSFNIDEVLGRPHPGYKLVEQMPLLNFTVDVKNTGDRVSDYTAMAFVNTTAGPAPHPNKWLVGFDRLSAVEPGSAKTMVIPVTVDSLARTDEEGNRVLYPGRYEVALNNEREVVLGFTLTGEKAVLFKWPKEEQLIAPQ
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase xlnD, 1,4-beta-D-xylan xylohydrolase xlnD, Beta-xylosidase A, Beta-xylosidase xlnD, Xylobiase xlnD.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUON_SALSV
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD2_DANRE
Sequence: MAPSTQEDDTVSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDTPACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAATCKDLVYFV
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Adenylate kinase 2, mitochondrial, AK 2, ATP-AMP transphosphorylase 2, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: UBIA1_DICDI
Sequence: MSTTINRNEKTKQVVNKTKEIKTESSQQQQQKPPISKLMGIILATRPWSLTISVTSVLVGSALAFREIREFDSIMLSIILVGAVSLQALGNVVNSFYDCKNGNDTKEKSADRTMFDFGLTEGNIINLIWYLLIQCAICLGLMIFRMDNIKCIVENILPLGAFGFILNISYTAAPIGLKYIGLGDLTIFLCFGPILVQSAFISQTHYHDSLAYFYSIPLALTIVAVLHVNNTRDIKADTEAGSITLASKLGFKNCYYIYAGLYLFAYIYLFKLSLDIDKYILNLPLILIPKIISLINQFKNKKLEDLTEKTGQLSFFFGGLNAIGVLLSMQ
What is the function of this protein?
Prenyltransferase that mediates the formation of menaquinone-4 (MK-4), a vitamin K2 isoform.
What are the official names of this protein?
UbiA prenyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BVGS_BORPE
Sequence: MPAPHRLYPRSLICLAQALLAWALLAWAPAQASQELTLVGKAAVPDVEVALDGDDWRWLARKRVLTLGVYAPDIPPFDVTYGERYEGLTADYMAIIAHNLGMQAKVLRYPTREQALSALESGQIDLIGTVNGTDGRQQSLRLSVPYAADHPVIVMPIGARHVPASNLAGQRLAVDINYLPKETLARAYPQATLHYFPSSEQALAAVAYGQADVFIGDALTTSHLVSQSYFNDVRVVAPAHIATGGESFGVRADNTRLLRVVNAVLEAIPPSEHRSLIYRWGLGSSISLDFAHPAYSAREQQWMADHPVVKVAVLNLFAPFTLFRTDEQFGGISAAVLQLLQLRTGLDFEIIGVDTVEELIAKLRSGEADMAGALFVNSARESFLSFSRPYVRNGMVIVTRQDPDAPVDADHLDGRTVALVRNSAAIPLLQRRYPQAKVVTADNPSEAMLMVANGQADAVVQTQISASYYVNRYFAGKLRIASALDLPPAEIALATTRGQTELMSILNKALYSISNDELASIISRWRGSDGDPRTWYAYRNEIYLLIGLGLLSALLFLSWIVYLRRQIRQRKRAERALNDQLEFMRVLIDGTPNPIYVRDKEGRMLLCNDAYLDTFGVTADAVLGKTIPEANVVGDPALAREMHEFLLTRVAAEREPRFEDRDVTLHGRTRHVYQWTIPYGDSLGELKGIIGGWIDITERAELLRKLHDAKESADAANRAKTTFLATMSHEIRTPMNAIIGMLELALLRPTDQEPDRQSIQVAYDSARSLLELIGDILDIAKIEAGKFDLAPVRTALRVLPEGAIRVFDGLARQKGIELVLKTDIVGVDDVLIDPLRMKQVLSNLVGNAIKFTTEGQVVLAVTARPDGDAAHVQFSVSDTGCGISEADQRQLFKPFSQVGGSAEAGPAPGTGLGLSISRRLVELMGGTLVMRSAPGVGTTVSVDLRLTMVEKSVQAAPPAAATAATPSKPQVSLRVLVVDDHKPNLMLLRQQLDYLGQRVIAADSGEAALALWREHAFDVVITDCNMPGISGYELARRIRAAEAAPGYGRTRCILFGFTASAQMDEAQRCRAAGMDDCLFKPIGVDALRQRLNEAVARAALPTPPSPQAAAPATDDATPTAFSAESILALTQNDEALIRQLLEEVIRTNRADVDQLQKLHQQADWPKVSDMAHRLAGGARVVDAKAMIDTVLALEKKAQGQAGPSPEIDGLVRTLAAQSAALETQLRAWLEQRPHQDQP
What is the function of this protein?
Member of the two-component regulatory system BvgS/BvgA.  Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.
What are the official names of this protein?
Virulence sensor protein BvgS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EBSB_ENTFA
Sequence: MLRIYVDAATKGNPGESGGGIVYLTDQSRQQLHVPLGIVSNHEAEFKVLIEALKKAIANEDNQQTVLLHSDSKIVVQTIEKNYAKNEKYQPYLAEYQQLEKNFPLLLIEWLPESQNKAADMLARQALQKFYPNKK
What is the function of this protein?
Seems to play some role in the cell surface expression of a chromosomally encoded receptor, named enterococcal binding substance (EBS), that mediates mating aggregate formation.  Might interfere with the synthesis or assembly of EBS and function as a cell wall hydrolase.
What are the official names of this protein?
Putative hydrolase EbsB.
What is the protein family that this protein belongs to?
Belongs to the RNase H family. EbsB subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Cell wall location was proposed in PubMed:8226689 based on a low sequence similarity to a cell wall hydrolase and a penicillin-binding protein. However, this protein has a best similarity to ribonucleases H which are expected to be cytoplasmic.
Protein: DPOL_HBVA5
Sequence: MPLSYQHFRKLLLLDDETEAGPLEEELPRLADADLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPIFNPEWQTPSFPKIHLHEDIANRCQQFVGPLTVNEKRRLKLIMPARFYPNSTKYLPLDKGIKTYYPDHVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELHHGRLVIKTSQRHGDEPFCSQPSGILSRSSVGPCIRSQFKQSRLGLQPHQGPLATSQPGRSGSIWARVHSPTRRCFGVEPSGSGHIGHRASDASSCLHQSAVRKAAYSHLSTSKRQSSSGHAVEFHSFPPSSARSQSQGPVFSCWWLQFRNTQPCSNYCLSHLVNLLEDWGPCTEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGSTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRINNNQHGTLQNLHDSCSRQLYVSLMLLYKTYGWKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQDHIVQKIKHCFRKLPVNRPIDWKVCQRLVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLSKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRETFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSQKYTSFPWLLGCTANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPYRPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: YIHI_MANSM
Sequence: MSRQKKSRNIVDVMPQRKSDKSQISPASYARPSKKLTRYELDAKAREDKKKKKHKGLTSGSRHSRSEQHNNQQMQEKRDPRLGSRKKVPLVVEFVNNPEKGQFIQPVQVQPAEEKVKKLDPMLELEQLENNECLNQLLDALDEGKTISAEDQKFVDECLDRIAQLMDELGIEDEEESEDDLLRTFEKIDINQFK
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: BT3L4_XENLA
Sequence: MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEVKQITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKASKPEDIEEEDDDVPELVGNFDEASKNEAN
What are the official names of this protein?
Transcription factor BTF3 homolog 4, Basic transcription factor 3-like 4.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
Protein: RLMF_SHEFN
Sequence: MTRSTTPPMRAKHSSAKRSPSRSAAKVNPVSVKPNKPLLSKALHPRNAHLQGYDFATLIIAMPALAAFVRPNPYGNPSIDFADPKAVKSLNAALLLSEYHINGWDIPEGYLCPPVPGRVDYLHYIADLLAVKGKVVKGASIRGLDIGTGANGIYPLLGIQTYGWQFVASDIDPVSIDNVAKIAQQNEKITAHLQLRLQPQPEHIFKNIIAADERFDVTLCNPPFHSSLAEASEGSLRKVKNLAKNQQQKHGQQSRKLAVSQAKPTLNFGGQKAELWCQGGEQQFLANMIKQSRDYANQVLWFTSLVSKSDNLKPCYQLLKQLNAVEVKTIEMTQGNKATRILAWSFLTPAIHQQWATLRP
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_ANTAG
Sequence: MKQKYWNINLEEMMEAGIHFGHQAAKWNPKMKPYIFTERRGIHILNVTKTARLLSEACDFVANAASKGKQFLIVGTKYQAADLVASAALKARCHYVNQKWLGGMLTNWSTIEKRLRKFEDLQTKKNMGALDELPKKEAANLERQLAQLQKYLGGIRYMTNLPDIVIIVDQQKELTAIRECINLNIPTICLVDTDCDPDLTDISIPANDDARASIRWVLDKLTSAIQEGRCNSTKI
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOZ_NITSB
Sequence: MRLEKIAAKALENVGFDRYLLSIAVAKRANELATGKEPLVEVDVKKYKYTDIALMEIAEGKLKIEVEKES
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NAC41_ARATH
Sequence: MEKRSSIKNRGVLRLPPGFRFHPTDEELVVQYLRRKVTGLPLPASVIPETDVCKSDPWDLPGDCESEMYFFSTREAKYPNGNRSNRSTGSGYWKATGLDKQIGKKKLVVGMKKTLVFYKGKPPNGTRTNWVLHEYRLVDSQQDSLYGQNMNWVLCRVFLKKRSNSNSKRKEDEKEEVENEKETETEREREEENKKSTCPIFYDFMRKDTKKKRRRRRCCDLNLTPATCCCCSSSTSSSSVCSSALTHTSSNDNRQEISYRENKFCLFL
What is the function of this protein?
Transcription activator of the mannan synthase CSLA9.  Recognizes and binds to DNA-specific sequence of CSLA9 promoter.
What are the official names of this protein?
NAC domain-containing protein 41, ANAC041.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_STRT1
Sequence: MSSGKIAQVVGPVVDVAFATGDKLPEINNALVVYTDEEKSRRIVLEVALELGEGVVRTIAMESTDGLTRGLEVLDTGRPISVPVGKETLGRVFNVLGDTIDMEAPFADDAEREPIHKKAPTFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERSREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEDKTLVGRARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILEGKYDNLPEDAFRSVGPIEDVVAKAKAMGY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSP1_ANTGO
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PUR7_BIFAA
Sequence: MEKLEKLYEGKAKQLYATDDPEVLWVEYKNSATAGDGEKKEDFAGKGRLNNLITTLIFDLLKKRGIDSHLVARVGETSQLVKKVTMFPLEIVLRNTAAGHFCSRLGVEEGIELKEPVLEYFLKNDELHDPFVNDDDLVALDVCTREDLAEIAPLARRINEALIEIFAKIDVKLVDFKIEMGRTSDGTLLLADEITPDSCRLWDQRDHSGKVEHLDKDLFRRDLGDIIPAYEEIESRLAELAKSEGIEVAE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYDND_COXBN
Sequence: MRTHYADKVDSSLIDQTITLCGWVHRRRDHGGLIFIDLRDREGLVQVVCNPTESTVFKVAESLRNEYVIKVTGKVHKRPEGTVNPHIPSGEVEIAASDITLLNKSKPLPFNIDEYQEVSEEVRLKFRYLDLRRPEVAQRLKMRSYIIREIRRFLDERGFLDIETPMLTKSTPEGARDYLVPSRTHPGQFFALPQSPQIFKEILMVAGFDRYYQIVRCFRDEDLRADRQPEFTQLDLEMSFVEEKDIQQLMETMIRHLFSTFLNVPLPDPFPRITYDEAIKTYGTDRPDLRNPLTLVDVTDLMKSVEFKVFKEPANNPHGRIAVLRLPKGAELSRKAIDDYTQFVGIYGAKGLAYIKVENIDNGTGGLHSPILKFLPENVIAEILKRTQAQSGDILFFGADKAKIVNESLGALRDRLCADLNLYEGQWKPVWVVDFPMFDREDVGDWQALHHPFTALQETDPEKVIANPGDVLSRAYDIVLNGSEIGGGSIRINDIGMQYAVLKVLGISKEMAEAQFGHLLMALQFGSPPLGGIAFGLDRLVAIMTGASSIRDVIAFPKTQTAQCPLTNAPAQVETLQLETLGLKVSKHRK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCIN_PIG
Sequence: TSKPVQNRELQGYESTDFXGYFKGGLKYKAGGVASGFNHVLTNXLSAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGSEIYQWFGSSCNKYERLKASQVATGIRDNERNGRSQLIVVEEG
What is the function of this protein?
Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane.  In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+).  Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity).  Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity).  Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (By similarity).  Regulates chondrocyte proliferation and differentiation (By similarity).  Inhibits cell proliferation and tumorigenesis.  Signaling is mediated by MAPK, p38 and JNK pathways (By similarity).
What are the official names of this protein?
Scinderin, Adseverin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, podosome.
Protein: TMCAL_CLOPE
Sequence: MNITGIITEYNPFHLGHELHLKSSKEITNCDGVICVMSGNFVQRGLPALTDKWTRTKMALEAGVDLVVELPTLFATSSAEFFAFGAVSLLNSLNVVNNICFGSECGDIDLIKKLSEIIINEPPLFKEYLKDYLKEGLPFPKARSEALMKYLDDNNYKIDFSYLEKVLNSSNNILAIEYCKSLYKLQSSIKPFTIQRLGADYNDEELSKNEIASASAIRKSIYTSNMEESLDFMPEYSYNLLKNTSFSDLDKMFDLVKYAIVSNPNVLKEIPEASEGIDNKIIQNIGKANSLDELINLCKSKRYSYTRLNRILCHVLLNVNKDLLSLRKSSPNYVRILGFNNKGREILKEIKKNSEINIVNKLSKAKADPLLEFDIKATNIYSFLNPSVKINSDYLISPIIFR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMD_HELPY
Sequence: MRLKHFKTFLFITMAIIVIGTGCANKKKKKDEYNKPAIFWYQGILREILFANLETADNYYSSLQSEHINSPLVPEAMLALGQAHMKKKEYVLASFYFDEYIKRFGTKDNVDYLTFLKLQSHYYAFKNHSKDQEFISNSIVSLGEFIEKYPNSRYRPYVEYMQIKFILGQNELNRAIANVYKKRHKPEGVKRYLERIDETLEKETKPKPSHMPWYVLIFDW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamD.
What is the protein family that this protein belongs to?
Belongs to the BamD family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.