PharMolix/UniProtQA huggingface dataset:
Protein: AGO1_LEIBR
Sequence: MLALNAGSQYPGRGRGRGRGDGGNRVHKHDGINRYHGGFRGGRGGGGGGFRDGDMRECRERESWAVSAAQANARTLARVPVPVETNCFPIDLSEGRFHNYIVSFEFLENATDMAGDMWKISLQNELLRTIRKNRTAEKRTRTSAEVEDLCVCTGQAILAPAKLSVEDGFSIECTRKEKVSRNNTEERHYRVRIRYDGEVSLKLPEHAQWVNKIIAFGLADTYSEHIGSDYVDMKSTVERGGDLVTMDAISLNALRIVKQSGSTTAMMDVLQLDVSTKASTKTKCSDEMRRLRQQNPQGFRRAVNEALVGISVTTVFGEPTFLKVKAIDFNILASSPTMFKTNPEETFVEYFKRKYDAIIDPTLPMLYCIFADRTKMSRRMPYPADSLLLNKLNEAQLSKLPILCSIYPNERMKRIKAALERVLASPLMITVLQQYGVRIQPQFVKVSGRVLPAPTIYVPSGPNMFNRINTAEYTGQAGFALGLKDLQHPSQPCEFKTLLMDEYFMHGNITHWLQKYNVALPSPRKTSFDSAAQRITEGPGTFAMVKLRTKEAGAYNNFKERFARSSIVSQMAVVDLTRNVPQMITQQVAAKIGQLCFVADVDEAGKSFACRPLLIVGAVVGTAMNTMLEKYKSINVRLYTITFVAFLANGKSWKPYCMHHQVKGEEHVLYEDSDAASSHMSSTTLTVRRQNANEVLNNRFPDFLKEVTAHFKLNGKGSKGTMVLYRGAMTDAEVGFTANMDLVMEQVLPNWDTATVVVHPRSHFRMAWDPTTVFPHETASAYAGLSNVPRGFSTTDCRIILADSDPYTPVDSFYLSAANCTLGHAANTYYLVQKRAASISLMDLQKLTYNMCYMYPNKPDALPLPLPIKCAYEYARKYGSLKSVKELPTRMRPTMHYL
What is the function of this protein?
Involved in RNA-mediated gene silencing (RNAi) of mobile elements and repeats including retroposons SLACS (Spliced Leader Associated Conserved Sequence), TATE (Telomere-Associated Transposable Element) and TAS-like sequences (Telomere Associated Sequence), and a family of 74-nucleotide long tandem repeats, CIR74 (PubMed:21060810, PubMed:23217017).  Predominantly binds to siRNAs derived from SLACS and TATE transposable elements and to a lesser extent to siRNAs from TAS-like and CIR74 elements (PubMed:23217017).
What are the official names of this protein?
Protein argonaute 1, LbrAGO1.
What is the protein family that this protein belongs to?
Belongs to the argonaute family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MESHJ
Sequence: MQKIRSIKKNWEFQAIINKKNQIVTNYLIFYYVKSDFFEIGISVPKKFANAVKRNYYKRQIKNALYILWKKGEIFLNFRVVLIARKNFLPLSFETKYQKLAKIFKELKRNEK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CT456_HUMAN
Sequence: MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDGMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI
What are the official names of this protein?
Cancer/testis antigen family 45 member A6, Cancer/testis antigen 45-6, Cancer/testis antigen 45A6.
What is the protein family that this protein belongs to?
Belongs to the CT45 family.
Protein: NNTM_SHEEP
Sequence: MANLLKTVVTGCSCPFLSNLGSCKVLPGKKNFLRAFHTHRILWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGAKEVLASDLVVKVRAPMLNPTLGIHEADLLKTSGTLISFIYPAQNPDLLNKLSKRNTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPILFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGQVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLASLYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMMDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK
What is the function of this protein?
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity).  May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (By similarity).
What are the official names of this protein?
NAD(P) transhydrogenase, mitochondrial, Nicotinamide nucleotide transhydrogenase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PNT beta subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: RL21_OLEA2
Sequence: MYAIIETGGKQFRVEEGCKIFVEKLAADAGSEIAIDKVLMLGGDKFAVGAPYVENAKVTAEVIEHGRGEKVITFRKWRRNDSRKKQGHRQDYTALKIKTITA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TGT_TOLAT
Sequence: MKFELKKTEGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVKDTGAQILLGNTFHLWLRPGQDIMRKHGDLHDFMNWHGPILTDSGGFQVFSLGHIRKIKEEGVHFRNPINGEKIFLSPEKSMEIQNDLGSDVVMIFDECTPYPATHDVAKKSMEMSLRWATRSRQRFDELENKNALFGIIQGGVYEDLRDVSLKGLLDIGFDGYAVGGLAVGEPKEDMHRILKHVCPQIPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFTTDGVVKIRNAKYKDDVTSLDAECDCYTCKNYTKSYLHHLDRCNEMLGARLNTIHNLRYYQRLMQGLRDAIDAGTLDDFVADFYQRQDKPVPSLD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: G6PI_PARPJ
Sequence: MTQNSLPSWSSLQTHYDKIRDAHMRDWFAPENDPAPTRAERFAFAGGGLAADFSKNRITEETLKLLVQVAREAGVEKRRDAMFAGDIVNPTEGRAVLHTALRATDPKAPFYAQVQAERKKMAVFADQVRSGEWKGYTGKRIRYVVNIGIGGSDLGPKMVVHALHHLATPEITTHFVSNVDGADLYNVMQQIDPEETLAIIVSKTFTTLETMTNARSLRDWFIEKGCPESALAKHFVGVSANPAEVVKFGIAKENVFEMWDWVGGRYSLWSAVGLSIMIAIGPKQFDELLAGANEMDQHFRDAPLEKNLPVLLGMIGIWYRNFFGSQSYLVAPYSQALHFLPSYLQQLEMESNGKSARLDGAMVDYPTAAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTPEHPLVSHHPKLLANCFAQSEALMVGRTLEEAKKVAGADKPELAPHLVFPGNRPTTTLLVDALTARSLGALIALYEHKVLVQGTVWNINSFDQWGVELGKILGKVVEADLTAPSADVKKHDSSTSALIARARAALKK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_NEOYE
Sequence: MSRSIHKGPFIDVSLLKRIEALNISGKKEVLKTWSRASTIIPDMVGHTIAVYNGKQHFPVFVSDQMVGHKLGEFVPTRTFRTHVKGDRKARR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FOLD2_RHILO
Sequence: MSLPDDSRYLKGGPVAQRIIAAVREDAAIAKAEGFPPKLISITVGDTDAVDVYVRNQRAKAQLAGIDFEERRFPATITSGELEAAIHGLNADPRVTGIIIQRPVPAHISVKTLQAAVHPLKDVEGMHPASIGNIVYNQLDLAPCTAAASVELLKETGLDLKGLEVVVVGHSEIVGKPIAFLLMSEGATVTVCHHLTRSVAAHARRADALFVAVGKPRLIKADMVKPGAAVIDIGINSEIGPDGTSRIVGDVDTDSVKDVASWITPVPGGVGPITVAILLRNTMVALSRQRALYEATYGTADRLAAE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TERM_BPNF
Sequence: MARNSRIRITNNDKALYAKLVKNTKAKISRTKKKYGIDLSNEIELPPLESFQTREEFNKWKQKQESFTNRANQNYQFVKNKYGIVASKAKINEIAKNTKEAQRIVDEQREEIEDKPFISGGKQQGTVGQRMQILSPSQVTGISRPSDFNFDDVRSYARLRTLEEGMAEKASPDYYDRRMTQMHQNFIEIVEKSFNSDWLSDELVERLKKIPPDDFFELYLMFDEISFEYFDSEGEDVEASEAMLNKIHSYLDRYERGDVNLDLKGF
What is the function of this protein?
Hydrolyzes host peptidoglycans during virus entry.
What are the official names of this protein?
DNA terminal protein, Gene product 3, gp3, Protein p3.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus DNA terminal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Associates with the host bacterial nucleoid through its N-terminal region.
Protein: PTH_RHIEC
Sequence: MLIIAGLGNPGSKYAGNRHNIGFLAVDAIHRRHSFSPWSKKFKAAIAEGELGGEKVLLIKPQTYMNLSGEAVGEAMRFYKLQPADLVAIYDELDLPAGKARLKTGGGHGGHNGIKSLDAHCGKEYRRLRLGIGHPGVKEMVQNHVLGDFAKADNAWLEPLLDTLADNADMLVRNEDSQLMNKIALALGGKADEEKPRKDSEKKPAGQSHIRQARNNNQPKLPATGPMADMLKKMFGNKGE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_PLAF7
Sequence: MTDDKKKGKFIVFEGLDRSGKSTQSKLLVEYLKNNNVEVKHLYFPNRETGIGQIISKYLKMENSMSNETIHLLFSANRWEHMNEIKSLLLKGIWVVCDRYAYSGVAYSSGALNLNKTWCMNPDQGLIKPDVVFYLNVPPNYAQNRSDYGEEIYEKVETQKKIYETYKHFAHEDYWINIDATRKIEDIHNDIVKEVTKIKVEPEEFNFLWS
What is the function of this protein?
Catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), the immediate precursor for the DNA building block dTTP (PubMed:18477629, PubMed:19126267, PubMed:31934749, PubMed:20353400).  Can also phosphorylate dGMP and to a lesser extent GMP, dUMP and dIMP (PubMed:18477629, PubMed:19126267, PubMed:31934749, PubMed:20353400).  Can use either ATP or dATP as phosphate donors in presence of Mg(2+) (PubMed:18477629).
What are the official names of this protein?
Thymidylate kinase, PfTMK, PfTMPK, Thymidine monophosphate kinase, Thymidylate/guanylate kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ARMP1_ARMGA
Sequence: MDSASLAVVVWAILLVLWLRRIFGQRSSLPLPPAPPGYPVIGNLLDLANNDVHIRARHWSRNFDDDVISLKVLGKTMIILNSPTAVSDLFDKRASNYSDRPDMPMIVDFIGWDWTFALMRYGPRWKEHRRVFNNHFNIGTSGASEDRHIQLRICRELLSLMFQSPSKYLENLRHYTGHIILKRTYGHTVVDEEDPYIRLVEAASQSTSEAAVPGAFLVDLFPSMKYIPEWFPGAQFKRKAREWRKLSEAMINAPYDMAKGKFDEGNAEACFVSACLEQNKTASGQGLSEELIKDTAAVAYAAGADTSVSTLTTFILAMTLYPDVQKAAQAELDALLGGERLPDFGDKTRLPYVTAILKEVLRWIPVLPMAVPHRAVNADTYKGYYIPAGAFVYGNAWAILHNPDIFADPETFRPDRFIENPTLLNPIDNGVFGFGRRACAGRVMALDTMWIAMASILAVFDISKAVDERGNEITPPVKLSPGTISHPAPFPCIIKPRSKAALELITQDD
What is the function of this protein?
Cytochrome P450 monooxygenase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable).  The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene (PubMed:21148562).  The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity).  ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity).  The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity).  The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity).  The role of the NAD(+)-dependent enzymes remains unknown (By similarity).  Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity).  The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity).  Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity).
What are the official names of this protein?
Cytochrome P450 monooxygenase ARMGADRAFT_974139, Melleolide biosynthesis cluster protein ARMGADRAFT_974139.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MGME1_MOUSE
Sequence: MKLPLTFCRLLSRLNRFSVKASPPVSFSTFSYLCSQKKKNSYEAVDQAKYSRLVRSVLSRGPAQTPESLFKEDDVLYGPVSKHKAAEPEPQARVPQHCFPIFNEERTGKPHTDASSSPLKIPLQRNSIPSVTRILQQTMPPEQSFFLERWKERMVLELGEDGFAEYTSNVFLQGKQFHKALESILSPQENLTGGEEHPQCGYIESIQHILTEISGVQALESAVQHEALKYVGLLDCVAEYRGKLCVIDWKTSEKPKPLIRNTYDNPLQVVAYMGAVNHDAHYSFQVQCGLIVVAYKDGSPAHPHFMDEELCSKYWAKWLLRLEEYTEKQKNLSAPEPA
What is the function of this protein?
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance.  Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates.  Necessary for maintenance of proper 7S DNA levels.  Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair (By similarity).  Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
What are the official names of this protein?
Mitochondrial genome maintenance exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the MGME1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y4231_VIBVU
Sequence: MRKSVIATGLALMMAVPFAANAADYVIDTKGAHASINFKVSHLGYSFIKGRFNTFSGDFSYDQNNIAASKVNVVVDTRSLDSNHAERDKHIRSGDFIDAGKFNTATFTSTKVMDKGDGKLDVMGDLTLHGVTKPITIAAEFVGAGQDPWGGQRAGFIGTTRLELADFNIPVMGTSSYVDMELHVEGIKK
What are the official names of this protein?
UPF0312 protein VV2_0231.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNY_CLOB8
Sequence: MVTAVMILIDVIVLLILGIVVYKTIQNISKAKIESLEKEAEEILVRAKKDAEATKKEAILEAKEELHKLRNDFDKESRERRNEIQRLERRVIQREEALDKKSELLEKKDETINQRMLEVDQVEARVQKLYEERRAELERISALSSEEAREILLDEIRKEITHDAALMIKDIESKAKEEADKRAREVITTAIQRCAADHVSESTVHVVALPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSSFDPIRREVARMALEKLIVDGRIHPARIEEMVERATKDVESSIKEEGEQAALETSVHGLHPEIIRLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGLDVTLAKRAGLLHDIGKAVDQEQEGPHALIGGDLAKKYHESPLVINAIAAHHSDVEMQSLEAVLVQAADAISAARPGARRETLEAYIKRLEKLEEIANSHEGVEKSYAIQAGREIRIMVKPDKVDDAGTIELARNLVKSVEEELEYPGQIKINVIRETRAVDFAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MAB11_COPCI
Sequence: MFAVFWTNLRCLGYNTFTCGVETPTTWGKVGSLDASSSTFTTYRGYPLAMAISAGTPACDSPDDNIRRAINTLRADLSALLRGESVAYSAFLSACTKFDGFAQSCHGMLSDDTLDLLYSFSESLLALSENMALLETKKEAESNKFTAEVMAILSDKTSGLDLSDDKNEPTSPTPAYVEPCARWLKDNWYNPYPSGEVRTQIARQTRTSRKDIDAWFIDARRRIGWNEVRRKHFENKRVDIVRAASIFTGPQSIPAEVDALPDHIELEFAGILSRARSLYEEKFSPSKLAVKLDTAVKDMTPSLKEQLKNDEARRKREASTVGIINQRARHAYPTPERSPASAAELLASPPSFAIDSDKLPSVGRKRRRSLESDETVSSPLCKRPRSQSVFCELSPVKGLPSPSPSTQDELLETSAAPSPQPSLLPKLTPTDSARSTGKRKRRLSDGFQYPAAKRPEIRPQVVSDPFPATSSEHWEQWFREHVLSSPELTLTGDIPPAVTTDAPDSNTPLDIQLFNFPLIPDLPPSVPVVPAPTAELNIIEPLEVPAVTQVNVDPEATALDHTFSWMASDFPPPLQSTNTFPSSSPFSALDGMSLPFPDTRSSAFLPDPSLWSNISDPDLDFSTVFSQPSTNSAMTSSIQVPLQPTWLTSRSLSEQEREAKRKELEELEARAQAIRAEISAP
What is the function of this protein?
Has a major regulatory role in sexual and asexual development.  It may bind DNA itself or it may have a role in preventing DNA-binding of another protein.
What are the official names of this protein?
Mating-type protein beta1-1.
What is the protein family that this protein belongs to?
Belongs to the TALE/M-ATYP homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF3_SERMA
Sequence: MKGGKRVQPARPNRINREIRAQEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSTKEQKEEQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGPEMAHQQIGMEVLNPLRKDLCEDMDLAVVESFPTKIEGRQMIMVLAPKKKQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFX_DESVM
Sequence: MPNMLEVYKCVHCGNIVEVMHAGGGDLVCCGEPMKFMKEGTSDGAKEKHVPVIEKTATGYKVKVGSVAHPMEETHWIEWIELIADGRSYTRFLKPGDAPEAEFCIQATEVSAREYCNLHGHWKA
What is the function of this protein?
Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center.  Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity (By similarity).
What are the official names of this protein?
Desulfoferrodoxin, Dfx, Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: RL34_BORBU
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKGGRLILSRRRAKGRMKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NTPPA_BACP2
Sequence: MNQLILASQSPRRKELLDLAGFSYDIQASHLKEEINRNLSPAENVQWLAEQKANDIQRLNPKAVVIGADTIVAIDGKCLGKPKDKKEAAFMLQLLSGKTHQVLTGVTVQSENRKETFYEQTEVTFWTLTQNEIDRYIETGEPLDKAGSYGIQGKGALFVQKIDGDYFSVVGLPIAKTVRVLETFGITPF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_PHOLL
Sequence: MDLLTLLLEKKLADHLTFPETINAHWLAEGVLQLIPHEEGNRSLVISAGIHGNETAPIEILIQLLAQLAEGTLALKNNVLIIFGNLPAMRTNRRYLHDDLNRMFGGRYLNFPLGNERSRAAELENVVNRFFAEPSVSSTNIRWHIDLHTAIRASHHEQFALLPAQNRPFSAEFMQWLHDSDIDALVYHREKAGTFSHFLSEKFGADSCTMEMGKAMPFGENDLTRFQKITDALYGLISLSQITARIKFELKHYQVINSIIKSHDSFQLHIPADTLNFTELPEGFEIASQHDHHWKIKFPAKFILFPNAEVANGLRAGLLLALNKK
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: PANB_HELAH
Sequence: MSMQTAKTKKITLNHLQAKKNHEKIIAITAYDALFAQMFDPIVDVILVGDSLNMSFFNQNDTLSASLEMMLYHTKAVCMGAKTPFIITDMPFGSYKDEKTALKNAIKVYKETQASAIKLEGGKEKAKLVKTLTNEGVIVVGHIGLMPQFVRLDGGYKIKGKNEEQQKKLLEDALSLEEAGVGLLVLEGITTPIAQVITQKIKIPTIGIGSGKDCDGQILVWSDMLGFFDSFKPKFVREYLKGKELVQKAIEQYADDVKKGFFPNELESYH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFXN4_MOUSE
Sequence: MEPNLQFWISERQAFFRRFCQWMDLLDPVNMFISIGSIEKSRQLLFTTEDAPKHYLDNQVIKDAWNKSLSTVHPDSSKLIPHLFRPAAFLPVTAPMVFLLMMPDTGIKSIILTQGCLYGYTTAFNITNGNASYSHGPVERTLLGAGVSVSSTFIGLIPHLFQMKYPPNNFWLKRTLPIVFLAQVSGMNVFASRSFENHRGIEVMDKEGHVVGHSRKAGRKAIKDTAKSRAVLFGTSALAPELFIHIFKRTRFYPQTLLSLVILRMSSTFFMMGLMVPVSFSMFPQIGQIQCSQLEEKIQSSTEEKELFYYRGV
What is the function of this protein?
Mitochondrial amino-acid transporter (By similarity).  Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity).
What are the official names of this protein?
Sideroflexin-4.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NQRE_PSYIN
Sequence: MEHYISIFVRSIFMENMALAFFLGMCTFLAVSKKVKTSMGLGVAVIVVLGISVPVNQIIYFNLLAPGALAWAGFPAADLSFLGFITFIGVIAALVQILEMVLDKYFPALYQALGIYLPLITVNCAILGGVLFMVQREYNLMESLVYGVGSGVGWMLAIVLLAGIREKMKYSDVPAGLRGLGITFTTAGLMAIAFMSFSGIQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_CLOBB
Sequence: MRKAIIAGNWKMNKTVDEAVKVVEELKPLVKDATCDVVVCPTFVCLDAVKKATAGSNIKVAAQNMHFEESGAFTGEVAPGMLEAMGIEYVVLGHSERREYFNETDEAINKKVKAAFAHNITPIVCCGETLEQRESGVTNNFIACQIKVDIAGLTKEQAEKVVIAYEPIWAIGTGKTATKEQANETILAIRNVVVEMYGKEVADKVRIQYGGSVKPNTITEQMAMSDIDGALVGGASLKAEDFSGIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.