PharMolix/UniProtQA huggingface dataset:
Protein: PGP_METS3
Sequence: MNIDAIAVDIDGTITDNKRRLCYSAMEAIRKAEDAGVPTIIVTGNIVTYAYATLVLLGASGGVVGENGGVIFKENYNNNQIKTVVDRTYVNAADKHLKERLGSKFDKNISNDNMYRLTESVFYKTITKKELEEGLKGFEYLDKIELYDSGFALHVTDKRVNKGSSLKYLCNENGIDMENVMAMGDSENDEAFLKEAGMKVAVGNAEDFLKKNSDYVCKNNYGDGVKEAIEKFVL
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: H2B7_CHICK
Sequence: MPEPAKSAPAPKKGSKKAVTKTQKKGDKKRKRARKESYSIYVYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B 7, H2B VII.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TATB_BURTA
Sequence: MLDLGLSKMALIGVVALVVLGPERLPRVARTAGALFGRAQRYINDVKAEVSREIELDALRTMKSDFEQAARNVENTIHDNLREHERDLNAAWNSAVSSGDPAAADASGGLGATSDEPSWRTVAAAPAKRRNWRVKKTATPVWYKRATMRRTQVQSGAARVARHQPSSLRRPARFF
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GCST_SHEPC
Sequence: MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHHAVRQDAGMFDVSHMTVVDVIGTDACAFLRKLLANDVARLKVPGKALYSGMLDENAGIIDDLITYYLTDTFYRVVVNSATREKDLAWIAKQSQGFDITVTERPELAMIAVQGPNAKAKAAAVFSADQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPEDEAQALWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMDETINPLAANMGWTIAWEPTDRDFIGRKALEALRDAGTDKLVGLVMEEKGVLRHDMPVFFTDAAGVEHQGVITSGTFSPTLGYSIAMARVPNQIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: KAD_MYCTU
Sequence: MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTKLGVEAKRYLDAGDLVPSDLTNELVDDRLNNPDAANGFILDGYPRSVEQAKALHEMLERRGTDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNRMKVYRDETAPLLEYYRDQLKTVDAVGTMDEVFARALRALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Has a broad specificity for nucleoside triphosphates, being highly active with ATP or dATP as phosphate donors, and less active with GTP or UTP.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
Protein: HOLD_HAEIN
Sequence: MNRRDLLLQEMGISQWELYRPEVLQGSVGISVAENIRLITVSDENISSSPLLADVLLSLNLKKENCLCLNYDQIQHMECKQPIRYWLLSENSDQIDRTLPFCKQAEQVYRSPSWQQFQSNHQAKRALWQQIQQP
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The exact function of the psi subunit is unknown (By similarity).
What are the official names of this protein?
DNA polymerase III subunit psi.
Protein: FIBG_RAT
Sequence: MNWSLQLRSFILCWALLLLSPTGLAQYTATRDNCCILDERFGSYCPTTCGISDFLNSYQTDVDTDLQTLENILQRAENRTTEAKELIKAIQVYYNPDQPPKPGMIEGATQKSKKMVEEILKYEALLLTHESSIRYLQDIYTSNKQKITNLKQKVAQLEAQCQEPCKDSVRIHDTTGKDCQDIANKGAKESGLYFIRPLKATQQFLVYCEIDGSGNGWTVLQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISMQSTIPYALRIQLKDWSGRTSTADYAMFRVGPESDKYRLTYAYFIGGDAGDAFDGYDFGDDPSDKFFTSHNGMHFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKSSTPNGYDNGIIWATWKTRWYSMKETTMKIIPFNRLSIGDGQQHHMGGSKQVSVEHEVDVEYP
What is the function of this protein?
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix.  Has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen gamma chain.
What are the subcellular locations of this protein?
Secreted.
Protein: CATD_CANLF
Sequence: MQPPSLLLLVLGLLAAPAAALVRIPLHKFTSVRRTMTELGGPVEDLIAKGPISKYAQGAPAVTGGPIPEMLRNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSALSGLAGIKVERQTFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVEKNIFSFYLNRDPNAQPGGELMLGGTDSKYYKGPLSYLNVTRKAYWQVHMEQVDVGSSLTLCKGGCEAIVDTGTSLIVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPDVTLKLGGKLYKLSSEDYTLKVSQGGKTICLSGFMGMDIPPPGGPLWILGDVFIGCYYTVFDRDQNRVGLAQATRL
What is the function of this protein?
Acid protease active in intracellular protein breakdown.  Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation.
What are the official names of this protein?
Cathepsin D.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space.
Protein: M2OM_HUMAN
Sequence: MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
What is the function of this protein?
Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate.  Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity.  Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity).  Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed:21448454).  Involved in the regulation of apoptosis (By similarity).  Helps protect from cytotoxic-induced apoptosis by modulating glutathione levels in mitochondria (By similarity).
What are the official names of this protein?
Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, alpha-oxoglutarate carrier, Solute carrier family 25 member 11, SLC25A11.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: 2PS_GERHY
Sequence: MGSYSSDDVEVIREAGRAQGLATILAIGTATPPNCVAQADYADYYFRVTKSEHMVDLKEKFKRICEKTAIKKRYLALTEDYLQENPTMCEFMAPSLNARQDLVVTGVPMLGKEAAVKAIDEWGLPKSKITHLIFCTTAGVDMPGADYQLVKLLGLSPSVKRYMLYQQGCAAGGTVLRLAKDLAENNKGSRVLIVCSEITAILFHGPNENHLDSLVAQALFGDGAAALIVGSGPHLAVERPIFEIVSTDQTILPDTEKAMKLHLREGGLTFQLHRDVPLMVAKNIENAAEKALSPLGITDWNSVFWMVHPGGRAILDQVERKLNLKEDKLRASRHVLSEYGNLISACVLFIIDEVRKRSMAEGKSTTGEGLDCGVLFGFGPGMTVETVVLRSVRVTAAVANGN
What is the function of this protein?
Polyketide synthase, which uses acetyl-CoA and two condensation reactions with malonyl-CoA to form triacetic acid lactone (also called methylpyrone), a precursor of phytoalexin.  May participate in insect and pathogen resistance.
What are the official names of this protein?
2-pyrone synthase, 2-PS, G2ps1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RL29_PSEFS
Sequence: MKANELREKSAQQLNEQLLGLLRDQFNLRMQKATGQLGQSHLLSQVKRDIARVKTVLNQQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HSLO_PSEPK
Sequence: MSDLPDTDFTQRFIFDERDVRGEWVSLDDSYAAVLARHEYPQPVQVLLGELMAATALLVGAMKFDGLLILQARSAGPIPLLMVECSSEREIRGMARYEADQIPAGATLSQLMPDGHLTLTIDPVKGQRYQGTVDLDGANLSECFTNYFVQSQQLNTRFWLNAQGGKARGLLLQQLPRDRQPDDEEREDSWQHVVALAKTLKPEEWTEGNETLLHRLYHEDAVRLFDIQPLRFNCSCSRERSGNALVSLGEHDAKALVDECGGTVEIDCQFCNERYFFDASDVAQLFAGGGTDVASETRH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBOX2_MOUSE
Sequence: MSEAEASVVATAAPAATVPATAAGVVAVVVPVPAGEPQKAGGGAGGGGGAASGPAAGTPLHAPGPRTPGNQATAASGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGARAANVTGPGGVPVKGSRYAPNRRRFRRFIPRPRPAAPPPMVAEAPSGGTEPGSEGERAEDSGQRPRRRRPPPFFYRRRFVRGPRPPNQQQPIEGSDGVEPKETAPLEGDQQQGDERVPPPRFRPRYRRPFRPRPPQQPTTEGGDGETKPSQGPTDGSRPEPQRPRNRPYFQRRRQQPPGPRQPIAAETSAPINSGDPPTTILE
What is the function of this protein?
Major constituent of messenger ribonucleoprotein particles (mRNPs) (PubMed:10076007, PubMed:12297523, PubMed:12648488).  Involved in the regulation of the stability and/or translation of germ cell mRNAs (PubMed:15031116).  Binds to Y-box consensus promoter element (PubMed:10076007, PubMed:12297523, PubMed:12648488).  Binds to full-length mRNA with high affinity in a sequence-independent manner (PubMed:10076007, PubMed:12297523, PubMed:12648488).  Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity (PubMed:10076007, PubMed:12297523, PubMed:12648488).  Its binding with maternal mRNAs is necessary for its cytoplasmic retention (PubMed:10076007, PubMed:12297523, PubMed:12648488).  May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (PubMed:15665108).
What are the official names of this protein?
Y-box-binding protein 2, FRGY2 homolog, Germ cell-specific Y-box-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRIB2_MOUSE
Sequence: MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFEISCYQESLAPCFCLSAHSNINQITEILLGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSGFGAKEACDQLVPDVNMEENLDPFFN
What is the function of this protein?
Interacts with MAPK kinases and regulates activation of MAP kinases.  Does not display kinase activity (By similarity).
What are the official names of this protein?
Tribbles homolog 2, TRB-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=May associate with the cytoskeleton.
Protein: PYRR_CLOPS
Sequence: MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGVKIPVASVDITLYRDDLTNVSDTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIMDQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEIIKVQIKEIDGTDSVEIYEN
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: ALG3_KLULA
Sequence: MVEEGANKTVGAPTVGDDQQPKEFVRPPFTPFQDILDAFNYLMWNPEANAIAMPVLILLESIAMKFIQNKVSYTEIDYTAYMEQIWMIQNGERDYSQIKGGTGPLVYPAGHVFIYKIFEWVSDGLENISEAQDLFRYLYVITLMIQFMCFGLLNIPPGYAIFAILSKRLHSVYVLRLFNDCFTTLFMSLAVLVMILCAKYKIRGFLVLIGSSFYSMAVSIKMNALLYLPGVLLTIYLLERCNTFKIVLNLAVMVIWQVIIAIPFWKEYPWEYLQSAFNFSRQFMYKWSVNWQMVDEEVFLDPLFHRSLLISHVIVLVVFLFYKLIPTNMNTPAGLLKIGKANLLHPFTDAVFSAMRVNAEQIAYILLVTNYIGVLFARSLHYQFLSWYHWTLPVLLNWANVPYPLCVLWYLTHEWCWNSYPPNATASTLLHACNTSLLLAVFLRGPANSKSGDNETTHEKAE
What is the function of this protein?
Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Asparagine-linked glycosylation protein 6, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RK14_GUITH
Sequence: MIQTQTYLTVADNSGAKKIMCIRILGGNRKYASIGDVIIGVVKDATPNMPVKRSDVVRAVIMRTKNTIRRKDGMSIRFDDNAAVIINKENNPRGTRVFGPIARELRDKDFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PKNJ_MYCBO
Sequence: MAHELSAGSVFAGYRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFVREADVAAGLDHPNIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAATMTTARAVYVIGEVAKALDYAHQQGVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTGLTSTGSVLATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLTGEAPFAAGAGAAVAVVAGHLHQPPPTVSDRVPGLSAAMDAVIATAMAKDPMRRFTSAGEFAHAAAAALYGGATDGWVPPSPAPHVISQGAVPGSPWWQHPVGSVTALATPPGHGWPPGLPPLPRRPRRYRRGVAAVAAVMVVAAAAVTAVTMTSHQPRTATPPSAAALSPTSSSTTPPQPPIVTRSRLPGLLPPLDDVKNFVGIQNLVAHEPMLQPQTPNGSINPAECWPAVGGGVPSAYDLGTVIGFYGLTIDEPPTGTAPNQVGQLIVAFRDAATAQRHLADLASIWRRCGGRTVTLFRSEWRRPVELSTSVPEVVDGITTMVLTAQGPVLRVREDHAIAAKNNVLVDVDIMTPDTSRGQQAVIGITNYILAKIPG
What are the official names of this protein?
Serine/threonine-protein kinase PknJ.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LSPA_BURM1
Sequence: MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALGVGATLVICFLLKRHGHQRLFSLSLALILGGALGNVIDRLVYGHVIDFLDFHLGGWHFPAFNLADSAITIGAVLLIYDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y644_MYCBO
Sequence: MRIGVGVSTAPDVRRAAAEAAAHAREELAGGTPALAVLLGSRSHTDQAVDLLAAVQASVEPAALIGCVAQGIVAGRHELENEPAVAVWLASGPPAETFHLDFVRTGSGALITGYRFDRTAHDLHLLLPDPYSFPSNLLIEHLNTDLPGTTVVGGVVSGGRRRGDTRLFRDRDVLTSGLVGVRLPGAHSVSVVSQGCRPIGEPYIVTGADGAVITELGGRPPLHRLREIVLGMAPDEQELVSRGLQIGIVVDEHLAVPGQGDFLIRGLLGADPTTGAIGIGEVVEVGATVQFQVRDAAAADKDLRLAVERAAAELPGPPVGGLLFTCNGRGRRMFGVTDHDASTIEDLLGGIPLAGFFAAGEIGPVAGHNALHGFTASMALFVD
What are the official names of this protein?
Uncharacterized protein Mb0644c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv0874c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS19_PSEU2
Sequence: MPRSLKKGPFIDLHLLKKIEVAAEKNDRKPVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAGTRTYRGHVADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: VP2_PESV
Sequence: MSWIAGAMQGAGLLGDLAGTIGQIVLHNKQLNIMNSFNQAQIQLAKDQLKQNQQLANQYYEFNANLPVNQYNSAVSAGFDSVSARQLAGSREVRYLGGQQTPLVHQGQIHQMMFSPKHLMQAQHVVGTFSRGMPGVTPSKGLPRPQGVTAKVPVAGATTTHSKV
What is the function of this protein?
May be a minor structural protein present in one or two copies per virion.  May play a role in RNA genome packaging (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the sapovirus VP2 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ATP6_ANADF
Sequence: MTAASLVTLALSLSLAQAAGHAGEHGAPAPEVATPAEGHGARDAAGAATDPHGAAAEHGAAAHEDPAQHGAAGAEAGHDESLGAVMMHHVADGYVLELPGFCGGLSWACHVDLRDVFGTEHVSEIDAHGHAVERNVSGPLVFGKVDMTPTKHVVMMWIASAILLLVVFAAVRKKSLVPRGLYNFIEMLVQFVRNEIAVKNIGEKDADRFVPYLVSAFFFILFLNLFGLVPFAATATANISVTVMMAVFTFLITQYAQIRAVGVGGYFAHMTGGVPKSLWPLWFIMIPVEFLGLFTKPFALTVRLFANMVAGHFVILALLGLIFALNSQWIAIASVPMALSIYMLELFVAFVQAYIFTMLSSLFIGSVVAHHGHEDEHEEHGHGAAATGGAHGSHGSHVAGASPGHG
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXO_CHAGB
Sequence: MTLQFPIQAPARYAGETEPVKRPREFACFSYDKDHKFRLDDSSMKWYYPPEIGTNLSHGYDTFIKHDDSVDEHLDSLLKTIADHEQQTGGPIDAHIVTWRGMLTKVGGSDASFLSLWFEMNATLYRLTFTSGYKFETLSTIPRPWGETTRDYIENRDNEVTNNKEQYCSVVRTGFGKSIVCLGGEVDAIWDAKPETPGKPINWVELKTTAEIHTHNDRFKFDRKLMRYWIQSFLLGVPKIIVGYRTQDGILSGVEEFSTLSMPQDVQRRKTAKWDGNVCIKFASLFLDWLRQSINDGGVWRIRRENKSDHIELFKVEEVGHGSIITDEFMNWRIKLSLNKDKPPGFEPSDAADAEPSMAEEPVPETASASGAY
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
What are the official names of this protein?
Decapping nuclease RAI1, NAD-capped RNA hydrolase RAI1, DeNADding enzyme RAI1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METXA_LISIN
Sequence: MTLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFEDDAPGWWDDYIGPGKTIDTDKYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIKDIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYADITDSIINIASPLAAGPDAIGYNLIMRMAILNDPDFNGGNYIGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPAAFSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFSKIKIPYLLIGITTDQLFRIHDLRRGYELLKEWDVPVTYHEVASEYGHDAFLVEKEVPKFEPLIRSFLNNLPVKSI
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_GLAP5
Sequence: MARNVFCAYLKQEAEGLDFQLYPGELGKRIFDSISKQAWAEWIKKQTMLVNEKKLNMMNPEHRQLLETEMVNFLFEGKEVHIEGYVPVESK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: ULAR_SALA4
Sequence: MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLFSRADQIAMLITGKNANPQVLQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT5_GIBZE
Sequence: MSSHDPSRFDDSEDEEDFNPAPADLSDEEQDDDHQKVKRGSSPAPRDDDDDEDERPSKSRHADDDEEEEEEEEEEEDTGRRRDDDDDEDEEEEDEEDEDIQQGHRRKRRKERGANFFDIEAEVDDEDEGEDDEMLGEEIGDFITNDHPDDIAETGDDDRRHRELDRRRDMDSSMDAEKQAEILRQRYGNRRSGKGFRDVSVVPKRLLLPSVDDPSIWAVRCKEGKEREVVFSIMKRIEERAGTKDELAITAAFERGGIESVMKGFVYVEARRQTDILKGLDSMMNVYPHSKMILVDIKDMPELFRISKTPTLEPGAWVRLRRPPKHNGDLAQVIDVTENGLEARVRFIPRLDYGMRDDALSADGKRKRPFGNGPKPPQRLFSEIEARKRNPRAIQGNPSTGTWTYNNEEFENGFQVRDVKIQQLTVTDVNPSLEEVTRFASGAEDGTENLDLKALAHSLKDSNALATYLPGDVVEVYTGEQKGVVGKAMRVHSDVVSITVTEGELVGQEIDVPIRALRKRFNVGDHVKVIGGSKFRDEVGMVVNIRDDKVTILTDQTNTEITVFSKDLREASDIGGQGSLGQYSLHDLVQLDPTTVGCVVKVDRESLVALDQFGTPRQVMPSQISNKIPKRKTAVAVDRHGSEIRLEDVVKEYTGQQRQGKIIHIHRSYIFLHSNDNKEHAGVFVTKANMVNTVAAKGGRVNTAAATGPDLTAMNPALKLHKNGSENKPVPPPRSFGKDKAIEQTVVIKKGAYKGLLGIVKDTTDTHARVELHTKSKTITVPKDCLAFKNRMTGATIDIASRGGRGGYGGGAGRGGGGDRVPGWQSGSRTPMAGGNSDRVPAWGSRTPAASGRTPAWKAQDMSGARTPAWADGSRTVNPYDGSRTAYGSGGRTPAWQAGGRTPAPGDAFGAGSRTPAYGGGDSWGSGSKTPAWGVTAPTPGASGGDAWGPGSYDAPTPGGALGAPTPGAMNAPTPGAYSAPTPAAISAPTPGGWQGGWGADSAPTPAAGAPTPGYYGAPTPGASYGPPETPAATGPRYTDDD
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT5, Chromatin elongation factor SPT5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SC64_TITOB
Sequence: GLRQKVQSLV
What are the official names of this protein?
Toxin To64, Toxin Tc64.
What are the subcellular locations of this protein?
Secreted.