PharMolix/UniProtQA huggingface dataset:
Protein: OMPN_ECOLI
Sequence: MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYFSDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGLKFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFFGLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAYTSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVANKTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADIGATYYFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane (By similarity).  Non-specific porin.
What are the official names of this protein?
Outer membrane porin N, Outer membrane protein N, Porin OmpN.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RSXA_SHIBS
Sequence: MTDYLLLFVGTILVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFTAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPIA_BRUSU
Sequence: MDEARKLKIAAAAEALTYVKDGMRLGIGTGSTAEEFVRLLAEKVKGGFRVIGVPTSERTAKLCEELGVALTTLEETPHLDLTIDGADEVDGELSLIKGGGGALLREKIVAAASDSMIVIADQSKVVETLGRFPLPIEVNRFGLGATIRAIEAAAVKCGLAGPLNLRLKDGSPFLTDGGHYIVDASFGRIPDPKTLSDALFAIPGVVEHGLFIGLARAAIIAGTDGIRTMNRS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: TRHO_PHOPR
Sequence: MAQYVVCALYKFVALEDFEAIRQPLTDVMEKNKIRGTLLLASEGINGTVASTREGIDALLAWFKQDQRLTDVVYKESFDENQPFNRTKVKLKKEIVTMGVEGIDPRHVVGTYVKPKDWNALIADPDVFVVDTRNDYEIEIGTFKHAVNPETESFREFPEYVEKNLDPEKHKKVAMFCTGGIRCEKSTAYLKEQGFDEVYHLEGGILKYLEEVPEKESLWEGECYVFDGRVAVDHQLEKGQYSVCNACRLPITDAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GPMA_CALS4
Sequence: MYKVVLLRHGESIWNMENRFTGWTDVDLSPKGIEEAKQAGKILKEKGFTFDAAFTSVLKRAIRTLWIVLDELDLMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKLWRRSAEVRPPALTKDDPRYPGNDPRYADLSEDEIPLTENLIDTINRVIPYWESTIAPTIKSGKRVIIAAHGNSLRGLVKYLDNLSNEEIMELNIPTGIPLVYELDENLKPIRHYYLADEEELKKKQQEVAEQGKARA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: TM10C_MOUSE
Sequence: MNVTVRFLRPFARCLVPYTFHRKRSHLYSGVLQRYMSSKAPSLSCHNKDSASPPEQLELDGWKATMKSSIQEDGVSEVSDKDEDSLASTRELIEMWRLLGKEVPEHITEEDLKTLMECASKSAKKKYLRYLYGKEKAKKAKQVKKEMKAEAREEAKRARLLETTAEEQQQDFMFLRLWDRQINIALGWKGVQAMQFGQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDSAYHRELVKRYREKWDKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRLNIATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNTGNWEEALKFVPRRKHTGYLEVSEQSQELVRKLKKTKTLNSFRKGSLNVRTWKR
What is the function of this protein?
Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation.  Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends.  Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity.  The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; TRMT10C/MRPP1 acting as the catalytic N(1)-methyltransferase subunit.  The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme.  In addition to tRNA N(1)-methyltransferase activity, TRMT10C/MRPP1 also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
tRNA methyltransferase 10 homolog C, Mitochondrial ribonuclease P protein 1, Mitochondrial RNase P protein 1, RNA (guanine-9-)-methyltransferase domain-containing protein 1, mRNA methyladenosine-N(1)-methyltransferase, tRNA (adenine(9)-N(1))-methyltransferase, tRNA (guanine(9)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: RS12_SALPC
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: AZOR_THIDA
Sequence: MRVLRVDASARVDDSVTRRLADLMLEILGERVPDLSVVRREAAGMPFVDDAWVGANSTDPEARDSAQRWALAKSDELVSEVMAADVLVIATPIYNFGVPASLKAWVDQVARARLTFRDTEYGPEGLLTGKKAYVLVASGGTEVGSDIDFATPWLEFVLGFLGITDVEVIAADRGMLRGDSARQNAAEHVADVLERDWPALAEAS
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: ISPF_MYCA1
Sequence: MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVVPTG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MNHA2_STAAN
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITDILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASIFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVPALRGVSGGNHQIDPLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKGYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YX14_CAEEL
Sequence: MVHATSQSASTEKNVKPCIETDTEEVNHKNQTKQYLSESESGDEYDEDLENAVSECSYQTATTSSVADTDISNICDQLLVLSTTNHKSMGSTRGKKKRGKTAKKAKKANRAQKITEEEIEAIKKKKKLDADKAYELRQEQMKIRQEKIDASDRNKIYRRLAQTAVDMLRKEERKLPPEIKQLDEDLEYYVENSKFYLRINLRDRYLETRVDEISEKYIGPALEHKTELLKIYEDLIKRSLQAFRLFMFLKTLNEKSVDYTKFEVLTLSFVMKGFEDDWLEVNGTYEENESYLSFEKNILHDIPETDQHVNAAEFVMNKLIYYAKKDDDGTLNLKECHMKEAYTGAGQLIAEYKQCTNAIAFLQDNRENLAYNLMEEWFLVSRKPSPIVL
What are the official names of this protein?
Uncharacterized protein C03F11.4.
Protein: TYPH_ALISL
Sequence: MYLPQEIIRRKRDNKVLTTEEINFFIQGVAKNTVSEGQIAAFAMAVYFNEMTMPERIALTCAMRDSGMVIDWSHMNFDGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLESIAGYNIMPNNDLFGKVTKEAGVAIIGQTGDLAPADKRVYATRDVTATVDNISLITASILSKKLAAGLDSLVMDVKVGSGAFMPTYEASEELAKSIVAVANGAGTKTTALLTDMNQVLASTAGNALEVREAIRFLTGEYRNPRLYEVAMALCAEMLVIANLAKDEQEACIKLQAVLDNGKAAECFGKMVFGLGGPNDIIENYDNHLETAQIIKPVFADKSGFVNTMDTRDLGMAVVGMGGGRRVASDTIDYAVGLSDMIRLGQTVDSNQPLAMIHARNEDQWQQAADAVKAAIVISEEQPEATPEVYRKVRSQDV
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: SRL4_YEAST
Sequence: MKKTIYKVLVSFYQYVGLGKKFHPSHDTVLIIGGSSNELGIELCETFIEDYHTKVINIDTIDSINGKNARRSEKLYTFISCKDFSDIKCLEESMLYLQNLEIIPTVLINNMQEGIESTLLKEDKFLRLDEESLNEFEKIVRYNLQSVILITKFCLSNIFPKVQAEAQEKAKGFYIVNISSVLTLKPCKSGTHFITSKCGINSFHDGITSELKLKDSNLNVKTLIAYLPSFESEAHWKRLSPSISKHLVHCLLEGRYGDTILESKRSIGDILLITGFKSSFT
What is the function of this protein?
May be involved in the regulation of dNTP production.  Induces the SOS system when expressed in E. coli, therefore, it may play a role in DNA metabolism and/or in genome stability.
What are the official names of this protein?
Oxidoreductase-like protein SRL4, Suppressor of RAD53 and LCD1 4, Suppressor of RAD53 null lethality 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PHOS_CANLF
Sequence: MEEAKNQSLEEDFEGQATHTGPKGVINDWRKFKLESEDSDSVPPSKKEILRQMSSPQNRDDKDSKERFSRKMSIQEYELIHRDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKITTIVVHIYEDGVKGCDALNSSFTCLAAEYPMVKFCKIKASNTGAGDRFSSDVLPTLLIYKGGELISNFISVTEQFAEEFFAGDVESFLNEYGLLPEREIHALDQTNMEEDTE
What is the function of this protein?
Inhibits the transcriptional activation activity of the cone-rod homeobox CRX (By similarity).  May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism.
What are the official names of this protein?
Phosducin, PHD, 33 kDa phototransducing protein.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Protein: PI5PA_HUMAN
Sequence: MEGQSSRGSRRPGTRAGLGSLPMPQGVAQTGAPSKVDSSFQLPAKKNAALGPSEPRLALAPVGPRAAMSASSEGPRLALASPRPILAPLCTPEGQKTATAHRSSSLAPTSVGQLVMSASAGPKPPPATTGSVLAPTSLGLVMPASAGPRSPPVTLGPNLAPTSRDQKQEPPASVGPKPTLAASGLSLALASEEQPPELPSTPSPVPSPVLSPTQEQALAPASTASGAASVGQTSARKRDAPAPRPLPASEGHLQPPAQTSGPTGSPPCIQTSPDPRLSPSFRARPEALHSSPEDPVLPRPPQTLPLDVGQGPSEPGTHSPGLLSPTFRPGAPSGQTVPPPLPKPPRSPSRSPSHSPNRSPCVPPAPDMALPRLGTQSTGPGRCLSPNLQAQEAPAPVTTSSSTSTLSSSPWSAQPTWKSDPGFRITVVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSELFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEDVDGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQGHRGLEEGGLGP
What is the function of this protein?
Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate.  Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro.  May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.
What are the official names of this protein?
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, Inositol polyphosphate 5-phosphatase J, Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase, Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Predominantly localized to membrane ruffles.
Protein: VE1_HPV21
Sequence: MADPKGSTSKEGLEDWCIVEAECSDVENDLEELFDRDTDSDISELLDDNDLEQGNSRELFHQQESKESEEQLQKLKRKYLSPKAVAQLSPRLESITLSPQQKSKRRLFAEQDSGLECTLTNEEDVSSEVEVPALDSQPVAEAQLGTVDIHYKELLRASNNKAILMAKFKEFFGVGFNDLTRQFKSYKTCCNAWVLSVYAVHDDLLESSKQLLQQHCDYIWIRGIGAMSLFLLCFKVGKNRGTVHKLMTAMLNVHEKQIISEPPKLRNVAAALFWYKGAMGSGAFTYGPYPDWIAQQTIVGHQSTEASAFDMSAMVQWAFDNNYLDEADIAYQYAKLAPEDSNAVAWLAHNNQARYVREVASMVRFYKKGQMKEMSMSEWIHTRINEVEGEGHWSTIAKFLRYQQVNFIMFLAALKDMLHSVPKRNCILIYGPPNTGKSAFTMSLIHVLRGRVLSFVNSKSQFWLQPMSECKIALIDDVTDPCWIYMDTYLRNGLDGHVVSLDCKHKAPMQTKFPALLLTSNINVHNEVNYRYLHSRIKGFEFPNPFPMKADNTPEFELTDQSWKSFFTRLWNQLELSDQEDEGENGESQRSFQCSARSANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: G6PI_FRATF
Sequence: MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINNYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKYFKETEFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGGTVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKKLAAHKVIPGNRPSTTILLDELSPYSLGALIALYEHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ACIBT
Sequence: MAGLSIWHVVIFAIVVILLFGTSKLKNIGKDVGGAVRDFKKSVREEDEAASLNSPRTIDAQVKTSESTSVKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ILVC_STRPI
Sequence: MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGNAKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SNP25_DROME
Sequence: MPADPSEEVAPQVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQLLK
What is the function of this protein?
May play an important role in the synaptic function of specific neuronal systems.  Associates with proteins involved in vesicle docking and membrane fusion (By similarity).
What are the official names of this protein?
Synaptosomal-associated protein 25, SNAP-25, Synaptosomal-associated 25 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Synapse, synaptosome. Note=Complexed with macromolecular elements of the nerve terminal.
Protein: DMSC_HAEIN
Sequence: MNTGLYELPLVFFTVLAQSAVGAWLVFTFVLLNEKNTKSRTYIHKVMFVILALLGIGFIASIMHLGLPIRAFNSLNRVGSSMMSNEIAAGAIFFTLAGFYWLIAILGKMPVSLGNVWRIVTALIGILFMYVMNQVYHITSIPTWNNALTSWSFYLTVVLGGLTLSYALLIPNKQREYQLQHLPSLFAIGVSLVAIVAIYQGFNLHNIHSAIQNAADLVPNYAIMTVTRLCLLSIVAFLLFRVKNIGLLGISVLLTLVAEGIGRVLFYGLHMTYGMTIGG
What is the function of this protein?
Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.  DmsC anchors the DmsAB dimer to the membrane and stabilizes it (By similarity).
What are the official names of this protein?
Anaerobic dimethyl sulfoxide reductase chain C, DMSO reductase anchor subunit.
What is the protein family that this protein belongs to?
Belongs to the DmsC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAX68_OPICA
Sequence: MNAKFILLLLVVTTTILLPDTQGAEVIKCRTPKDCADPCRKQTGCPHAKCMNKTCRCHRCG
What is the function of this protein?
Blocker of voltage-gated potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.8, OcKTx3.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METN2_RHOPA
Sequence: MNALPSSAEFSRAVGGDAVSREAVIRIEHLSKTFSDAAGPVLDDVSLTIRRGEIHGIIGRSGAGKSTLVRCINLLERPSAGRVIVSGREITSLRGRALRNARRDIGMIFQHFNVLSSHTVAGNVALPFKVAGLPRAEIARRIPPLLELVGLAHKADAYPSELSGGQKQRVGIARALALDPSVLLCDEATSALDPETTDQILALLRDINRKLGLTIVLITHEMHVVRDIATRVAVLDHGRVVEEGATFDVLAFPKSAVARSFLSGLVAHELPPPVAAQLLPAAVPGSDPVLRIVFTGTAAHDPIVADLVSVFGIQPNILHGRIDYVGDRPLGVLTLVAGGAGEKLPAVLSHLSSLGLVVEVIGHAVRSAVARRHSAAR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MS5L1_ARATH
Sequence: MRRRESRGAKGGGFLTPPPSWHTTRRVYIAMPISERKRSPLIENQESFRVRTGDSPYVRAKHAQLVSKDPNRAISLFWAAINAGDRVDSALKDMVVVLKQLNRFDEGIEAIKSFRYLCPFESQDSIDNLLLELYMKSGRITEVAELLEHKLRTLEQDKHYGGRIKIAKRSHEEQNNKTIEQEKARILGNLAWVHLQLHNYGIAEQYYRNALSLEPDNNKLCNLAICLIRMERTHEAKSLLEDVKQSLGNQWKNEPFCKSFERATEMLAEREQATVADKPEDLLTSSFSDNFSSRCSGGMKGKKALAGTSTELGNIHKTNSHASSESVEQNSPGLTTQPRECKWVDEEVDQSKWDATIGASRKLRFWTVGPVRSLRFGNDYQKNLKSVGTAASTTNDELHQFISSDADCMTSKARKLCPELIKDKEDNEKESERIASESSSAYAKITDIGQRKVLHIDQRKVRHIGQRSV
What is the function of this protein?
Probably involved in the regulation of cell division.
What are the official names of this protein?
Protein POLLENLESS 3-LIKE 1.
What is the protein family that this protein belongs to?
Belongs to the MS5 protein family.
What are the subcellular locations of this protein?
Nucleus.