PharMolix/UniProtQA huggingface dataset:
Protein: SNX4_BOVIN
Sequence: MEQAAPDPERLWQPAPLEPLSHPDAGLESMVGEETKGARDEGPGDGTMTENNFSLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHNDGQSVLTDSLWRRYSEFELLRNYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFIELKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKMLEEQIKEGEQQLKSKNLEGREFVRNAWADIERFKEQKNHDLKEALISYAVMQISMCKKGIQVWTNAKECFSKM
What is the function of this protein?
Involved in the regulation of endocytosis and in several stages of intracellular trafficking.  Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.  Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A.
What are the official names of this protein?
Sorting nexin-4.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC).
Protein: NADA_PHOLL
Sequence: MNQYIDFNSTIYPFPPKPAFLSKDEKKHYREKIKRLLKQQDAVMVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKRVLMPTLEAECSLDLGCPEKEFTQFCDDHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDYLDSQGKKIIWAPDRHLGNYVRKQTGADILCWQGACIVHDEFKTQALIRVKGLHPDAAVLVHPESPQAVIDLADAVGSTSQLIKSAQSLPHQKLIVATDKGIFYKMQQACPEKQLFAAPTAGEGASCRSCAHCPWMAMNGLQAIVQGLEQGGGQHEILVEKELREKALVPLNRMLDFAAQLK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_PSEAB
Sequence: MAKLTKRQKAIAEKVVAGKQYSFEEAAKLLAELSTIKFKESVDVAVNLGVDPRKSDQVVRGATVLPNGTGKSVRVAVFTQGPAAEAALAAGADKVGMDELAAEMKGGDLNYDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVRFRTDKNGIIHSSVGKVDFEPAKLQQNVEALLADLKRLKPSSSKGVYVKRVTLSTTMGPGLQIDLASLEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BETI_BRUC2
Sequence: MPKIEMEPLRRRELIDAAIRTIGQRGSLDVTVAQIAHEAGVSPALAHHYFGGKDKLILATMRHLLRELGRDLNAAIKQANTPHERIAAIIAVNFSAAQFAQETIAAWLTFYVHAQQSDDIKRLLRIYARRLHSNLVFALEQLTSRARANRIAEGAGAMIDGLYIRHALGADAPDAASAIALVEDYIAIQLSGQPSAEN
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: 1433_ENCCU
Sequence: MASKQYEEALQKANLSDMAERYDDMAKEMRLAVTLAHEDKHILNVMARNLFSVAYKNLVSSRRSSWRMLCSERQKLEGKDPSVVHVINEKIKVVEEELLRFCDEVLDIITTYILSLEEAQKNIEYNIFFLKMKGDYYRYKAEVVTGPEHSEVSKHAAESYKEATEKAKTLPPTNPIKLGLALNYSVFHYEILNDSEKACSIAKGAFDEAIKELDTLSEEHYRDSTLIMQLLRDNLTLWTSREEGNVMGDEGKGDPDEN
What are the official names of this protein?
14-3-3 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: CLPP_OLTVI
Sequence: MPIGVPKVPFRLPGEPSAQWVDLYNRLYRERVLFLCQDLDDELANQLIGIMLYLNAEEKSKDLYIYINSPGGSVTCGIAVYDTMNYIKADVTTICVGTAASMASFVLAGGTQGKRIALPHSRIMIHQPEGGSRGQASEVLSESEEVMRIRRQVGKIYAQRTGQPLRRISRDLDRDQFLSAREAKDYGIVDQVATS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RNH_SHEB2
Sequence: MTELKLIHIFTDGSCLGNPGPGGYGIVMNYKGHTKEMSDGFALTTNNRMELLAPIIALESLKEPCQVVLTSDSQYMRQGIMTWIHGWKKKGWMTSNRTPVKNVDLWKRLDKASQMHTIDWQWVKGHAGHAENERCDVLARTAAESKPTQPDLGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPZ_CHICK
Sequence: MVPSLLLLLTGLFRATEPAPRCETGQETLGQCQTAQKAKCVDISLSSCTDVTYTQTMYPNFLDQKSREVIEYSSEYILISVLHNLLQGECNPDLRLLGCSVLAPQCEKDKVIKPCRHVCENLKKNCLSAFDAIDMAWPYFLDCDRFFAGEEEGCFDPLAKLRGEVAVEEDLPSDFPATFIQFKHHSYSQMVSTLKKTASRCSHIATTYSIGRSFEGKDLFVIEFSTKPGHHELLKPEFKYIGNMHGNEVVGKELLYTLRSICVQKYLLGNPRIQTLINNTRIHLLPSLNPDGYERAAEEGAGYNGWVIGRQTAQNLDLNRNFPDLTSEAYRRAGIRGARLDHIPIPQSYWWGKVAPETKAVMKWMRSIPFVLSASLHGGELVVTYPYDYSRHPMEEKEFSPTPDEKMFKMLAKAYADAHPVISDRSEHRCGGNFVKRGGIINGAEWYSFTGGMADFNYLHTNCFEVTVEVGCEKFPLEEELFTIWHENRDALLNYMEMVHRGIKGIVSDKFGNPIKNARISVRGIQHDITTAADGDYWRLLPPGTYIVTAQAMGYTKVMKRVTLPIKMKRAGRVDFVLRPIEIWPNKLLRRPMEDMYDQYDPLELFDPHAQHAQARGGSQQVREKPWWWSYFSSLDLHKPLWLLKQH
What is the function of this protein?
Cleaves substrates with C-terminal arginine residues.  Modulates the Wnt signaling pathway, probably by cleaving some undefined protein.  Regulates the development of skeletal elements during development, probably by activating WNT4.
What are the official names of this protein?
Carboxypeptidase Z, CPZ, cCPZ.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RPOB_THEAQ
Sequence: MEIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGDKGKGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASKR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NUOA_BACAN
Sequence: MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLFLYPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYL_LACCB
Sequence: MAYDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVARMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNREINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVIDGKTERGGFPVVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPFDVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKTGVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIEGGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQRYWGEPIPVIHWEDGETTLVPEDELPLTLPEEADIKPSGTGESPLANLTDWVNVVDKNGRKGKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYARFWNLFLYDIGAIPNKEPFQRLFNQGMILGDNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDRVWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARKDDDLPLEYVEGFVKMLAPIAPHLMEEIWSRLGHDHSLTYAPWPSYDESKIKTDTYDMMIQVNGKLRGSITADVNESDDEIKQAALANDNVQKFTAGKDIKKIIVVPRKIVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNCG_HUMAN
Sequence: MSDNTTLPAPASNQGPTTPRKGPPKFKQRQTRQFKSKPPKKGVKGFGDDIPGMEGLGTDITVICPWEAFSHLELHELAQFGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
What are the official names of this protein?
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.
Protein: RLP22_ARATH
Sequence: MSNLRLRLLSLVSILYCIAALRCRPDQTETIKRFKNEFAFSSICRNDTNFFSGVVCDNTTGAVTVLELPGGCLRGTLRPNSSLFELSHLRYLNLSFNNFDSSPLSSAFGQLNNLEVLLLSSNGFTGQVPSSIRNLTKLTQLNLPHNKLTGDLPSLVQNLTKLLALDLSYNQFSGTIPSSFFTMPFLSYLDLSENHLTGSFEISNSSSKLENLNLGNNHFETEIIDPVLRLVNLRYLSLSFLNTSHPIDLSIFSPLQSLTHLDLHGNSLTLTSVYSDIDFPKNMEILLLSGCNISEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSFTGFNGSLDHVLANSSVQVLDIALNSFKGSFPNPPVSIINLSAWNNSFTGDIPLSVCNRTSLDVLDLSYNNFTGSIPPCMGNFTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKALPNLKVLTLRSNSFHGPMSPPDDQSSLAFPKLQILEISHNRFTGSLPTNYFANWSVKSLKMYDEERLYMGDYSSDRFVYEDTLDLQYKGLYMEQGKVLTFYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESLDLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIPQGTQIIGQPKSSFEGNSGLCGLPLEESCLREDAPSTQEPEEEEEEILEWRAAAIGYGPGVLFGLAIGHVVALYKPGWFIKNNGQNRLRGIRHP
What are the official names of this protein?
Receptor like protein 22, AtRLP22.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PRX5_RHIET
Sequence: MTMEKQVPIVTFRTRVRDESISGPNPYRWEDKTTDDYFSGKRVILFSLPGAFTPICSTFQLPDFESLYVEFKKNGIDDIYCLSVNDAFVMNAWGKSQGLKNVKLIPDGSGEFTRKMGMLVAKDNLGFGLRSWRYAAVINNGVVEGWFEEEGFGDNCATDPYGVSSPQNILKCLKAPAFV
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Prx, Glutathione-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
Protein: CYNR_ECOLI
Sequence: MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSITLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAQHHPLAVHEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQTAAAKAFLHMALDKCAVVGGNESR
What is the function of this protein?
Positively regulates the cynTSX operon, and negatively regulates its own transcription.  Binds specifically to the cynR-cynTSX intergenic region.
What are the official names of this protein?
HTH-type transcriptional regulator CynR, Cyn operon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_STAS1
Sequence: MSEEMNDQMQVRRQKLQELYDLGIDPFGQKFDRTSMATPLHEDWDQFSKEELHEKEEESHVSIAGRLMTKRGKGKAGFAHVQDLSGQIQIYVRKDQVGEDQFAIWNSADLGDIVGVEGVMFKTNTGELSVKAQSFTLLTKALRPLPDKFHGLQDIEQRYRQRYLDLITNQDSTQTFIKRSKILQEMRNYLNQQGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDITENMIRHISEKVLGTAKVTYGEETIDLESKWKRIHMADAVKEETGVDFFNIQSDEDAKIAAKEHGIEITDNMKYGHILNEFFEQKVEETLIQPTFVYGHPIEISPLAKKNAEDPRFTDRFELFIVGREHGNAFTELNDPIDQRARFEAQLVEKEQGNDEAHEMDEDFIEALEYGMPPTGGLGIGIDRLVMLLTDSASIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_SALSV
Sequence: MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIKEATAFGVMAVDESDKIIDFVEKPANPPAMPGDASKSLASMGIYVFDADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRDVGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLVSGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: RING4_BPCA1
Sequence: MNVNEFSNEFDVLYNNIMSNAAPGLNEYEKSVLLTKAQEEIVKNYFEPAGNKYGKGLDDSPKRQIDFSELIKVGEGVLNTSAPTITFDKRAKVYDLPADLFLVINEAVDTNAGTKQIVPISYSDYTRLMSRPYKEPVKYQAWRIITTSINNISVELIVNSNETITDYKVRYIRRPAPIITTNLSSEYGDVTINGVSTVSECELNPIIHSEILQRAVELAKAAYQGDLQASVELGQRSE
What is the function of this protein?
Forms the tail multi-ring barrel with ring protein 1, ring protein 2 and ring protein 3.
What are the official names of this protein?
Ring protein 4/5, R4, Gene product 34, gp34.
Protein: CSPLC_MAIZE
Sequence: MGAAGLKVPEMALRLCVVPLSLASLWEMASNAQADDTYGEVKFSDLSGFSYLVGVNAVTAAYAVASVLASSFKRPLAARYDWVVLVMDQASAYLLVTSASAAAELLQLARHGDRGVSWGEACSYFGRFCGKATVSLALHAAALACFAALSLVSAFRVFSSRCHPPPDADGQPPKHARDEEQRVYHY
What are the official names of this protein?
CASP-like protein 2D1, ZmCASPL2D1, Protein salicylic acid-induced 1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_ECOHS
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NADK_METMJ
Sequence: MKIVLVSRIDEADALRYTASLARELEGLGHEVALEEGTAAHLGEGGISFEEIDGDLVVVVGGDGSVLLTVHQMKKQVPVLGINWGEVGFLADLEPDEAGTFFAAHTEGFHIERRMRVSLSVNGVPLGDALNEGLVVTDRPAKMLRFGVYVDGTPAERFRADGLLVSTPTGSTAYAMSAGGPIVDPQIEGFLLVPLAPYMLSSRPHLISTGRNLEITLETEKPAHLVIDGQSTFELEKEATLTVKKSDQPALFVHTGKPFFEKVNHKLRNL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BHLB_BACSU
Sequence: MFENIDKGTIVRTLLLAIALLNQIMVMLGKAAFIINEEDINHLYDCLYTIFTIVFTTSTTTAAWFKNNYITAKGKKQKQVLKKENLFK
What is the function of this protein?
May be involved in the secretion of the autolysin BlyA.
What are the official names of this protein?
SPbeta prophage-derived protein BhlB.
What is the protein family that this protein belongs to?
Belongs to the SPP1 holin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CTAA_STACT
Sequence: MFKKRNLKWLSILATVIMAWVQLGGALVTKTGSENGCGASWPLCHGALLPQNLPIATIIELSHRATSALSLIVVLWLVITAWKNIGYIKEVKPLCIISVAFLLIQALVGAAAVLWQQNDYVLALHFGISLISFSSVFVLTLIIFDVDQKYEANKVHIDRKLRIYTWTMAICLYVGIYTGALVRHTKSSLAYGSWPLPFNDLIPHTEQDWVQLAHRTLALIASISVFLAFNYAIKHYQNNRTIRYGYTAALLLIILQIVTGALSIFTHVNLIIALLHALIITFEFGLIAYLIVLLLRSQRVEKVKQNAY
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFC10_HUMAN
Sequence: METSSRELQAAEYLEKHQIKEVVSYLTSALLFFRPEKPKEYLISLLERLRIAKVTGVAFPFFMDNSNIVAMFEMMDSSGRGTISFVQYKEALKTLGLCTEDEDLQDDGHKITLDKFKEEVNKRMKEI
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 10.
Protein: MMGE_BACSU
Sequence: MPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALRYPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGHPSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDHVLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATSRGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPAEFHAQTAAESAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYITAIGLLFGDITAQHYEAETANDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVHFKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETLQTMRVNEFVDMFCM
What is the function of this protein?
Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles (PubMed:28956599).  Has both 2-methylcitrate dehydratase and citrate dehydratase activities.  Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield 2-methyl-cis-aconitate, and the dehydration of citrate to yield cis-aconitate.  Cannot form isocitrate.  Uses either (2S,3R)- or (2R,3S)-2-methylcitrate (PubMed:28956599).
What are the official names of this protein?
Citrate/2-methylcitrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the PrpD family.
Protein: KRA3_SHEEP
Sequence: TGSCCGPTFSSLSCGGGCLQPRYYRDPCCCRPVSCQTVSRPVTFVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPTSCQAVVCRPCCWATTCCQPVSVQCPCCRPTSCQPAPCSRTTCRTFRTSPCC
What is the function of this protein?
The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins.  The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).
What are the official names of this protein?
Keratin, high-sulfur matrix protein, IIIA3.
Protein: AROK_PSEPF
Sequence: MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDREQAMIAELCAFDGVVLATGGGAVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLLRTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVLDILDRLAQLPPR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_POLNS
Sequence: MSSSNNSLNNKAQAWSARFAEPVDELVQRYTASIGFDQRFAMVDIAGSLAHAEMLATQKIISAQDLADIQKGMAQIQSEIEAGQFEWQLALEDVHLNIEARLTQLVGDAGKRLHTGRSRNDQVATDLRLWLRGSVDEIALTLKSLRVALLDLAEKHASTIMPGHTHLQVAQPITFGHHLMAYFEMFSRDASRLADLRARFNRLPLGAAALAGTTYPINREQVAKALGFDGTCNNSLDAVSDRDFAIEFCAFASILMMHVSRLSEELILWLSPRFGFIDLPDRFCTGSSIMPQKKNPDVPELARGKTGRVYGDLISLLTLMKGQPLAYNKDDQEDKEPLFDAVDTVQDTLRIFADMVPHIEVKSEAMKKAAEEGFATATDLADYLVKKGLAFRDAHEAVAHAVKACVGRNCMLTDLSLSELRFACGLDNRPELIGDDVFVLLTVDGSVQSRQHAGGTAPAQVLAAIKRGRADL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_DESVH
Sequence: MIRKTLAASCAVLLMAGCNAARQQASPLPPVAPPQTYVEPEQAAANPGSMFNDAEADLMFSDSRARRVGDIVLVKIVENAKAKNKADTTSERDSTNNYTVGAYFGQDSASINPMNPVGAFGGKVGTNALLQTGSKSKLDGKGETKRENTVTATIAARVVRVMPGGLLQVEGARETRVNDETQYIVLSGLVRSRDVASDNSVMSTQLADSRIAYYGKGVLADKQRPGWFSRLMDNLWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RECF_SALTI
Sequence: MSLSRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQPGRVIRHEQEAFVLHGRLQGEERETSIGLTKDKQGDSKVRIDGTDGHKIAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQRNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTFSFQRGWEKETDYADVLERSFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.