PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_BUCA5
Sequence: MLNNKIDFSKYDPKLWFAIEQEKKRQENHIELIASENYTSNYVMDVQGSQLTNKYAEGYPGKRYYGGCEYVDIIEELAIERAKKLFNADYANVQPHSGSQANFSVYTALLNPGDTILGMKLSHGGHLTHGSSVNFSGKMYNVISYGVDENGEINYEELLRLTKKYKPKMIIGGFSAYSGICNWKKMRFIADKADAYFVVDMAHVAGLVAAGIYPNPINYAHVVTSTTHKTLAGPRGGLILAKNGDDILYKKLNLSVFPGAQGGPLMHVIAAKAIAFKEALEPKFKTYQKQIVKNSKVMVERFLEKGYKIISGHTFNHLFLIDLTNKKITGKDADIILSKANITVNKNTIPNDLKSPFITSGIRIGTAAVTRRGFKENEVSKISDWITSILNNVDDHNNVLQIKKKVLEMCLKYPVYI
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GON2_SQUAC
Sequence: QHWSHGWYPG
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH-II, Luliberin II, Luteinizing hormone-releasing hormone II, LH-RH II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_STRGC
Sequence: MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVIDGKKYKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELNYLHEEGVTTDNLRISDRAHVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFRERLERNLAEKNRLFEKLYDSTAIKIDDIFEEYYEYGQQIKQYVTDTSVILNNALDQGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELFDEVGDRIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAYDLDGQRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRKLEDLPENARNYVRRVSELVGVRISTFSVGPDRDQTNILESVWSSL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TA2R4_PONPY
Sequence: MLQLFYFSAIIASVILNFVGIIMNLFIMVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIFFVSSNTERSVYLSAFFVLCFMFXDSSSLWFVTLLNILYCVKITNFQHSVFLLLKQNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTKRNNTSFNTHEGILSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMIYFLILYIPYSVATLVQYLPFYVGMDMGTKAICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).  In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 4, T2R4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: RL29_METMA
Sequence: MAILRTSEIRTMTIEERADELENLKNELVRERALTSAGGAPDNPGRIGEIRRTIARIKTIQHELNEI
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: YL042_YEAST
Sequence: MKISQFGSLAFAPIVLLQLFIVQAQLLTDSNAQDLNTALGQKVQYTFLDTGNSNDQLLHLPSTTSSSIITGSLAAANFTGSSSSSSIPKVTSSVITSINYQSSNSTVVTQFTPLPSSSRNETKSSQTTNTISSSTSTGGVGSVKPCLYFVLMLETIAYLFS
What are the official names of this protein?
Cell wall protein YLR042C.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: Y2083_RHOCB
Sequence: MSSNLRPLFWTLPLTRLTPAEWEALCDGCGKCCLNKLEYEDTGELEFTRVACRLLDGESCRCRNYEIRHQFVPECVRLTPKSLKKSVYWMPATCAYRLRYEGRPLEPWHYLISGDPETVHDAGQSVRGWTVSEAEVPEEDWQDYIIEDL
What are the official names of this protein?
UPF0260 protein RCAP_rcc02083.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: EFTU1_ECOHS
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP9_PHONI
Sequence: QKKDKDRFYGLM
What are the official names of this protein?
Tachykinin-like peptide-IX, P.nigriventer tachykinin peptides IX, PnTkP-IX, U29-ctenitoxin-Pn1i, U29-CNTX-Pn1i.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1553_YERPY
Sequence: MDMTNAQRLILSNQYKMMTMLDPENAERYRRQQTIVERGFGLQMRELDRDFGEMSEDTCRTIINIMEMHHALQVSWGNLKEKQDLDERRISFLGFDAATESRYLSYVRFMVNTEGRYTHFDSGTHGFNSQTPMWDKYQRMLAIWQSCPRQYHLSAVEISQIINA
What are the official names of this protein?
UPF0304 protein YPK_1553.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: ATP5E_ARATH
Sequence: MASNAAVPFWRAAGMTYISYSNICANIVRNCLKEPHKAEALTREKVHFSLSKWADGKPQKPVLRSDTPEV
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase epsilon family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: MDC1_PIG
Sequence: MEDTQVINWEAEEEEVEEGPSEPLGCNLQPVGQLRIFSSSYGPEKDFPLYLGKNVVGRMPECSVALPFSSISKQHAVIEILAWNKAPVLRDCGSLNGTQILRPPKVLGPGVSHRLRNRELILFADLPCQYHRLDVPPPLVSRGPLTVEETPRGQGGTQPHRLLLAEDSEEEVDSLSERCVVKGPKTSLTTVIPESDEEGPSPAPDGPGPPFAFNLNSDTDEEESQQPGAGEAPSAAETEQPKPVTTEIQLIKDQCPVKEKHKDARVKRAASNGVVPVGAILERSQPAGEDSDTDVDEGSGLPRRPAGAHSERAQPCGFIDSDTDAEEEGIPATPAVVPVKKRQIFHEVGTESPQAPGVAHAQESPAGSDTDIEEGEAPRTVPLDSSRASMMIDSNMDDEEEVSAALTLARLRESQAVPWNRDAGAGDHRAQPVALLDQSQASAGRDSDTDMEEEGLPLEKRGSLPKGPADKAHPEKSQPPLRGSDVKVEEDERSPGVHPGRSQASATVDAITQVEEKAPPRPAVTLSEQHQVPVAWTPQTDVEAEGDPAKLPVVHPAEARPPPAGGHEPDVEKNTSLAASAGADVRKSQLLAEGDAGTEWAVAILAQDRALGAGAQSVSARAQVGQDLPLVSREHLADVAVDTGAPGEATQTQREGTQALTERERELNVDRTIDSGDNRDDSEDLDLQATQCFVEGENQSPEAVPSMEDEPTQAFPSTLPQEPGPSCCSFQASGTLDEPWELLATQPFCPRESEASEIQPVDTHLEARGLCPSPPRAALPEQHPESPEPLGSQGGGRQTVEKATGTPRETAEGPTPERGPLERATKEPPSEGERGGMGEEGLPRGTQDREEKQVLAGVTQRQESDRTVKSTSTDGGLESLQVEIETPKEMQENEIEKQTLARDMLEREAEKPVAERESEAGGPEVKVPEAVQDRGPLRAEAEGTSQDQKGQASNLTPEPGAGVGYLQGLASAPAAPRSQAGGGGEAPVSPRRQQRGDLNCKMPPAEKSGVRAAFSPSLPSPHGDQESPEACLPPEPPEASAPLQNPLPSQSPKHPAPQSRLSPPPPPLEQSTPRTRPPQSQESPEPPFSSELDPPNPEPKVRPQGSPPLSPIPLEAHPTSPTDQAGSPEPTSRAARGGTHRSFEVTPMSVVPTALELQSSTSADQPVVPKPTLRAPWGRTHRSSVKTPEPNIPTAPELQPSTPTDQPVAPEPLSRATRGRTPRASVKTSEPVVPAAPEPQPSTPTDQPVVPKPTLRAPRGRTHRSSVKTPEPNIPTAPELRPSTPTDQPVAPEPLSRATRGRTPRASVKSPEQNVPTAPEHPQPSTPTDQPVTPKPTSRATRGRAHRSSVKTPAASEPLPSASTDQPITPKPTSRGRAHRSSAKTPELQPPTSTGQPVTPRPTSQATRGRTHRSSIKTPEPVVPTDPEPQPSTPTDQPITPELTSAATRGRTRRSSVKTPEPVVPTDPEPQPSTPTDQPITPKPTSWATRGQAHRSSVKTPEPHVPTDPEPQPSTPTDQPVTPKPTSRATRGRARKSSVKTPEPAVPTAAEPQPSASTDQPITPKPTSRGRAHRSSAKTPELQPPTSTGQPFTPRPTSGATQGRTHRSSAKTSQAVEPTAPDLEPPSPIGQPVTPKVIAEGGQNRILRSSRVGAVPGPTPPELQCPVPTEQPVPPEPIPRASCSRRPRATRKRESLTAHVGPDPCSAPPEPNSRSSRTQSLSTTPEPTLPQLPEAPAHAPQIPKVEAAGRPGFTLEPQPKATQKRKRPLAPADSPPLPKRLQRGEVPPKTVILEEEENPTARPGREEDAVIPEPGKRKRDQTEEEPRGVPSRSLRRTKPAQESTAPRVLFTGVVDARGERAVLALGGSLASSVAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGCFLPPDEYVVTDPEQEKNFGFSLREALSRARERKLLEGYEIHVTPGVQPPPPQMGEIISCCGGTVLPSMPRSYKPQRVVITCSQDFPRCSVPFRLGLPVLSPEFLLTGVLKQEAKPEAFVLSTLEMASA
What is the function of this protein?
Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle.  May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AX.  Also required for downstream events subsequent to the recruitment of these proteins.  These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis.  ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1 (By similarity).
What are the official names of this protein?
Mediator of DNA damage checkpoint protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin. Relocalizes to discrete nuclear foci following DNA damage, this requires phosphorylation of H2AX. Colocalizes with APTX at sites of DNA double-strand breaks (By similarity).
Protein: SECY_MYCTU
Sequence: MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVGNSWWDKFVGTYLSDPSNLVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAGGTVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WECF_ECOSE
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAAIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNDHIAALCAVHQQLGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIMM_STRP3
Sequence: MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDKDRFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYHQIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRVDVELMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNF1B_HUMAN
Sequence: MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW
What is the function of this protein?
Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:7900999, PubMed:17924661).  Binds to the FPC element in the cAMP regulatory unit of the PLAU gene (By similarity).  Transcriptional activity is increased by coactivator PCBD1 (PubMed:24204001).
What are the official names of this protein?
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CML13_ORYSJ
Sequence: MSTVKGQTRRERPRGARPHGLTKQKRQEIKEAFDLFDTDNSGTIDAKELNVAMRALGFEMTEEQINQMIADVDKDGSGSIDYEEFEHMMTAKIGERDSKEELTKAFSIIDQDKNGKISDVDIQRIAKELGENFTYQEIQEMVQEADRNGDGEIDFDEFIRMMRRTGYGY
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML13, Calmodulin-like protein 13.
Protein: RS16_STAAW
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TUSB_SALPB
Sequence: MLHTLPHCASGVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_LACH4
Sequence: MTIALFPGSFDPITNGHIETAKKAAEIFEKVYLVAMTNTSKHYLFSPGERADFARDALKDVANIEVLEKPDEITVDLAHELNAKAIVRGVRNSADFRYEQEIAGINKRLAPDINTILLFSSPENSFVASSMIKELAKFDKDVSQFLPEKAAKALRRKLGNEYAE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_HAHCH
Sequence: MSSSANSLNALSFDNSYARLPTHFYQKVAQTPLEDAHLISFNGDVAEALGLNRSQLDPEELARYCGGGGALETGESIAMKYAGHQFGHYNPDLGDGRGLLLGEVVTADNRRLDLHLKGAGRTAYSRFGDGRAVLRSSIREYLVSAAMNSLGVSSTSALCLVGSEEYTMRNGMEPCAMVLRVTPCHIRFGHFEHFYYLGQHDDLKLLADYCIERYFPQLQEADNPYLAMFNEVRNRTADLVAQWQSYGFVHGVMNTDNMSIIGETFDYGPFTFLDSYDPNFISNKNDTAGRYAFKQQPGIALWNLSALAQALLPLIPLDDLKRSLDDFADLYSAAFYGKMSQRLGLTQQGADGSLRQLIDDLLTLFAANNTDMNRFMRALSRYDGNESSLSFMSDLSCDSRGFSEWKARFCKHVDSSDVTLADRTQAMLQVNPEYILRNYMLEEAIREAHQGDYLPVQNLLKIVKNPFNAQPGAERYAEAPPDWAGAICLTCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: GASR_CANLF
Sequence: MELLKLNRSAQGSGAGPGASLCRAGGALLNSSGAGNLSCEPPRLRGAGTRELELAIRVTLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVVCKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIIATWMLSGLLMVPYPVYTAVQPAGGARALQCVHRWPSARVRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDEDSDSESRVRSQGGLRGGAGPGPAPPNGSCRPEGGLAGEDGDGCYVQLPRSRQTLELSALTAPTPGPGGGPRPYQAKLLAKKRVVRMLLVIVVLFFLCWLPLYSANTWRAFDSSGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
What is the function of this protein?
Receptor for gastrin and cholecystokinin.  The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCYA1_HUMAN
Sequence: MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESCKATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAEQAVAAGVPVEVIKESLGEEVFKICYEEDENILGVVGGTLKDFLNSFSTLLKQSSHCQEAGKRGRLEDASILCLDKEDDFLHVYYFFPKRTTSLILPGIIKAAAHVLYETEVEVSLMPPCFHNDCSEFVNQPYLLYSVHMKSTKPSLSPSKPQSSLVIPTSLFCKTFPFHFMFDKDMTILQFGNGIRRLMNRRDFQGKPNFEEYFEILTPKINQTFSGIMTMLNMQFVVRVRRWDNSVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDTHAVQIALMALKMMELSDEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSEIPGICHFLDAYQQGTNSKPCFQKKDVEDGNANFLGKASGID
What are the official names of this protein?
Guanylate cyclase soluble subunit alpha-1, GCS-alpha-1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, Soluble guanylate cyclase large subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_ZYMVC
Sequence: MASIMIGSISVPIAKTEQCANTQVSNRANIVAPGHMATCPLPLKTHMYYRHESKKLMQSNKSIDILNNFFSTDEMKFRLTRNEMSKLKKGPSGRIVLRKPSKQRVFARIEQDEAARKEEAVFLEGNYDDSITNLARVLPPAVTHNVDVSLRSPFYKRTYKKERKKVAQKQIVQAPLNSLCTRVLKIARNKNIPVEMIGNKKTRHTLTFKRFRGCFVGKVSVAHEEGRMRHTEMSYEQFKWLLKAICQVTHTERIREEDIKPGCSGWVLGTNHTLTKRYSRLPHLVIRGRDDDGIVNALEQVLFYSEVDHSSSQPEVQFFQGWRRIFDKFRPSPDHVCKADHNNEECGELAAIFCQALFPVVKLSCQTCRESLVEVSFEEFKDSLNANFIIHKDEWGSFKEGSQYDNIFKLIKVATQATQNLKLSSEVMKLVQNHTSTHMKQIQDINKALMKGSLVAQDELDLALKQLLEMTQWFKNHMHLTGEEALKMFRNKRSSKAMINPSLLCGNQLDKNGNFVWGERGYHSKRLFKNFFEEVIPSEGYTKYVVRNFPNGTRKLAIGSLIVPLNLDRARTALLGESIEKKPLTSACVSQQNGNYIHSCCCVTMDDGTPMYSELKSPTKRHLVIGASSDPKYIDLPASEAERMYIAKEGYCYLSIFLAMLVNVNENEAKDFTKMIRDVLIPMLGQWPSLMDVATAAYILGVFHPETRCAELPRILVDHATQTMHVIDSYGSLTVGYHVLKAGTVNHLIQFASNDLQSEMKHYRVGGTPTQRIKLEEQLIKGIFKPKLMMQLLHDDPYILLLGMISPTILVHMYRMRHFERGIEIWIKRDHEIGKIFVILEQLTRKVALAEVLVDQLNLISEASPHLLEIMKGCQDNQRAYVPALDLLTIQVEREFSNKELKTNGYPDLQQTLFDMREKNVCKAAAQFMARAKLAGKILCNRAIEAILDFYGKKFNPASKRRKARIFATICSRVFYHDPSTCEEHSRCRRA
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: TRHO_STRPN
Sequence: MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RPOA_BRASO
Sequence: MGETVTIQKNWQELIRPNKLQVTPGSDATRFATVVAEPLERGFGQTLGNALRRILLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISIKMQGEGPKRMVVKKQGPGAVTAGDIQTVGDIVVLNPDLQLCTLDEGAEIRMEFTVATGKGYVPAERNRPEDAPIGLIPIDSLFSPVRKVSYKVENTREGQILDYDKLTMTIETNGAISPEDAVAYAARILQDQLNVFVNFEEPRKEVAQEIIPDLAFNPAFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: DIVIB_BACIE
Sequence: MADGKVIDIEQKVPDFREQRRRKSRRRLVLYISILAFFLLFVYYFQSDYSTVGHVDVYGTDMVDEKWVVESSGLTDGVSMWSYPFHEAVEELMEHPVIVSVEAERNWPRSITLYVDEYRTVGYLRSAENGAFYPLLNDGSILNQEEFQGSHVDEPLISGMDAHSELGRLAHELDELDEMVTRRISEVVHEPDQGEHHLTLYTTDGFTVYTEINDFASNMTAYPAVAIQLNPEEEGILHMRMTPYFEREGQEEEEIEIEE
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: PVK2_SARBU
Sequence: AGLLVYPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, Neobu-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.