PharMolix/UniProtQA huggingface dataset:
Protein: URED_BACSB
Sequence: MKCTGVLQLSAAKKRQKTIISSCYHEGALKVSRPIYLEKDLPFLYLIHVGGGYVDGDVYLTNLDVEEEAELAVTTQSATKVYKTPKKPVVQQTNIHLKKGSVLEYLLDPLISYKGARFIQETTVHIEEDSGFFYSDVITPGWAEDGSLFPYDWIRSKLKVYKKDRLVLFDHLRLEPDEDMSGMLQMDGYTHIGTFLIFHQKADKTFLDRLYDEMEAFDSDVRFGMTSLPASGIILRILARSTGIIENMISRAHSFARRELLGKNGVTWRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MESHJ
Sequence: MNVNEIIKGPILTEKSYQLMSSGVYSFKVSPKTNRSETKKAVEYIFNVKVEKVNIFTVPKKEKKLGKSKGFTTKYKKALVKLMPGYTINLFEDESPQDQKDSETVSENTEEKAKIAKKKAELEAKNKEIAEKLAKKQAELAKKDSETNENQEKRIENQTENQENSAN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome (By similarity).
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UVRC_ENTFA
Sequence: MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSYFRGSHDTKTERLVSEIDDFEYIVTESNIEALLLEINLIHKNNPKYNIMLKDDKTYPFIKITNEKYPRLMITRKVLKDKALYFGPYPDVNAANETKKLLDRLFPLRKCNPSQKTPCLYYHLGQCLCPYAFDVDPQVYKDMVEEIKGFLSGGHTEIQDRLQEKMAYAAAHMEFEKAAEFRDQIKAIETVMTRQKMTNVDLIDRDVFGYAVDKGWMCVQVFFVRQGKLIERDVSIFPFYDDASEAFLTFIGQFYQENEHFVPKEVLIPDDIDKESVEALLATKVLQPQRGEKKKLVKLASKNAAVALNEKFDLIVRKQERTIGAVEKLGNAMNIPAPIRIEAFDNSNIMGTNPVSAMVVFIDGRPAKNEYRKYKIKTVQGPDDYASMREVIYRRYSRVLKEGLPFPDLILIDGGKGQVDVAKDVLANQLGVDIPVAGLAKNDKHKTSELLFGPNLEVVPLERNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFASKLDNIEGLGPKRKKNLLKEFKSLKNITAASVEELRKAGLPETVAKNVYRHLHQETTSEIEK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_ENT38
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDHAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSISLSRRLRELPLRVNRLKTGTPPRIDARTIDFSVLAQQHGDTPIPVFSFMGNAAQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQIQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARFSAEKEGWAPRRDQAYLGVLVDDLSTMGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLERIETERQRLKSTWVNPLADSVAEVNAHLAAPLSREASGEDLLRRPGMTYEQLVQMTPFAPGLDDAEAAEQVEIQIKYEGYIARQQDEIEKQQRNENTLLPEMLDYRQVTGLSNEVIAKLNDHKPVSIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_CLAM3
Sequence: MPTVLLTGFEPFDGDTSNPSWTAVQEVRDRWDGDAEIQVRQLPVDFAKVDDALRAALAEVDPDVVISVGLAGGIETLEVERVAINVDDARIPDNTGFQPIDEPVVDGGPAAYFSTLPIKAAVAAVRTKGIPAVVSQTAGTYTCNHVFYLLMHELRDRPGTRGGFVHIPYSTEEAIGTDRPYMRMDQLATALTAVVRATLANATDVKVGSGSLD
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_NEIMF
Sequence: MKRKNIALIPAAGIGARFGADKPKQYVEIGSKTVLEHTLGIFERHEGVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLETGLAAETDNILVHDAARCCLPSEALTRLIEQAGNAAEGGILAIPVADTLKRADGGNISATVERTSLWQAQTPQLFRAGLLHRALAAENLDGITDEASAVEKLGIHPLLVQGDARNLKLTQPQDAYIVRLLLDAV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RL32_PELPD
Sequence: MAVPKKKTSKSRKNMRRAHDFLTTQSVSVCPQCKSPKLPHRVCPTCGTYKGKEVLDVAKAS
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: EFG_RICCN
Sequence: MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVEMLKDRLGAKPLVIQLPVGIEENFKGIIDLIKMKAVIWKDEALGAEYFEEDIPADMKDKAEEYRAKLLDMVVELDDHVMEKYLSGEEVTAEEIKRLIRKGTISAAFYPVLCGSAFKNKGVQPLLDAVVDFLPSPIDIGIVKGMEVSTGEEKDFPISVTEPFAALAFKIMNDPFVGSLTFIRIYSGKITSGTTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDIDQQVILERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFRVSTDYETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKVCEIDYTHKKQSGGAGQFARVKIIFEPLKEVKDLKDEDKNKIFVFESKIIGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMQVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTANVPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_MARMM
Sequence: MSLLNDIDQLSQVRTDWTRETAGEIYRAPFNDLIFAAQSVHRQCHPANQVQTSQLLSIKTGGCAEDCGYCNQSAHFDTGLKASKLMPLDDVLDAAKKAKDGGATRFCMGAAWRELKTRDEDVICDMISGVKSMGMETCVTLGMLTDSQANKLREAGLDYYNHNLDTAPEDYGRVISTRTYQDRIDTLSRVRGAGIHVCTGGIVGMGEDEAARIGLLTELASMDPHPESVPINHLVAVPNTPLGDSKPLDGIEFVRTIATARILMPRSMVRLSAGREGMSRELQALCFLAGANSIFVGEELLTTPNPEQNEDFDLFKSLGIEPMRLGETGTVPAE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NSCC_TRIEC
Sequence: MGKQQETILIIGAGISGLATSRLLTNNGIPNIVFEASTPDRSQGFAISLQEFGYSTLLAALGDLPLSSLIRAVAPDRQIGGTGWIDQALRDNRTGELLVAPDLTTTKQTIVRANRNALRHWIADCGEDELDVRYGHKLQSIKGKLGDVTAIFENGAKYKGSLIIAADGVNSTYSPRRGS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
FAD-dependent monooxygenase nscC, Neosartoricin B biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: CYSC_SHESR
Sequence: MSNIVWHQHSVDQADRAKLKGQNPVLLWFTGLSGAGKSTLAGALERALFDAGFHTYLLDGDNVRHGLCKDLGFSVADRDENLRRVGEVAKLMVDAGLVVLSAFISPTREERDSIRARFPEGQFIEVHVSTPLSICEQRDPKGLYVKARRGEISNFTGISSPYEAPLSAELTIDTSKGDLASQVRALIDYLTAIEVINPSRLTASA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: NRFA_SULDE
Sequence: MKFKLLLAGSLVAVGAMALLASNINEKEKQRVELAKAPSEAGIAGKEKSEEWAKYYPRQFDSWKKTKEYDSFTDMLAKDPALVIAWSGYAFSKDYNSPRGHYYALQDNVNSLRTGAPVDAKTGPLPTACWTCKSPDVPRLIEEDGELEYFTGKWAKYGSQIVNVIGCANCHDDKTAELKVRVPHLNRGLQAAGLKTFEESTHQDKRTLVCAQCHVEYYFKKTEWKDAKGADKTAMVVTLPWANGVGKDGNAGVEGMIKYYDEINFSDWTHNISKTPMLKAQHPGFEFWKSGIHGQKGVSCADCHMPYTQEGSVKYSDHQVKENPLDSMDQSCMNCHRESESKLRGIVHQKYERKEFLNKVAFDNIGKAHLETGKAIEAGASDEELKEVRKLIRHGQFKADMAIAAHGNYFHAPEETLRLLAAGSDDAQKARLLLVKILAKHGVMDYIAPDFDTKDKAQKLAKVDIAALAAEKMKFKQTLEQEWKKEAKAKGRANPELYKDVDTINDGKSSWNKK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process (PubMed:7999130).  Has very low activity toward hydroxylamine, and even lower activity toward sulfite.  Sulfite reductase activity is maximal at neutral pH (By similarity).
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: EFG2_MYXXD
Sequence: MAREYPLDRYRNIGIMAHIDAGKTTTTERILFYTGAIHRMGEVHEGNTTTDWMVQERERGITITSAAISAFWARHDQRYRVNIIDTPGHVDFTIEVERSLRVLDGAITVFDAVNGVEPQSETVWRQADKYKVPRICFINKMDRVGADFEMSVGTIREKLGARAVRMQLPLGAEDKHRGVIDLLKMKALVFQDSEQGSHYEESDIPEEFKEAADAARAELLEAAAEQDDALTEKFLEGVELTEDEVRGAIRKGCLGLKLFPVFCGSAFRHKGVQPLLDAVVDYLPSPLEVPPIHGKTPNGEDAVRETRDDAPFSALAFKIMNDPAFQSQTLTFLRVYSGKLEAGTAVWNSVKGKRERISRLVQMRADKKDEITECYAGDICAVVGLKLAGTGDTLCDDKQPIILERMDFPEPVIDIAIEPKSTADQDKILQSLQRLAMEDPSFRVRTNEETGQTLIAGMGELHLEIIVDRLLREFKVDANIGKPQVAYRETVTTQVEMEGKYIRQTGGRGQYGHIWLRVAPNEPGKGFSFENKVTGGVVSKEFVDAVKAGCAEAMQNGPVAGYPMVDVKVEAFDGSMHDVDSSEIAFKIAGSLAFKDAVRMATPVLLEPIMNCEIVTPDDFMGDVIGDLNGRRGKVQGMTPRPGRVQAIQAQVPLAAMFGYSTDLRSRSQGRATYTMQFSHYAPAPKTALNR
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU1_ANOGA
Sequence: MPVPCGSSCGRNAFMRRPKTGDTLCKECFFLAFETEIHNTIQQEQLFRPGEKVAIAASGGKDSTVLAHVMNLLNKRYNYGLDLVLLSIDEGITGYRDDSLKTVAQNRDDYGMPLRVLSYQELYGWTMDRIVAEIGRSNNCTFCGVFRRQALDRGARLMEVDCVATGHNADDIAETVIMNILRGDTARLRRCCDIKTGSKEADTIPRVKPLKYSYEKEIVMYAHFKKLVYFSTECVFAPNAYRGHARAFLKDLEKVRPSAIMDIIHAGEQLQIKGTVKKPVRGVCGRCGFVSSQQPCKACVLLEGLNRGLPKLGIGKKSKGERMVALQEQQLREKAHLVKNDF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJC_HALH5
Sequence: MEGLGGFLIPLILMFAIFYFLLIRPQQKRQKQIQEMHNNLQRGDKIVTIGGLHGTIDSLDESTVVILVNDNRKLTFDRSAIREVVNPD
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
Protein: UXUA_EDWI9
Sequence: MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWSVVESVPVHEEIKTQTGNYQRHIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLPDGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKSYFDAMGEAEVTKLTANIIAGLPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRPILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLRATCREANPKSFHEGAHLQGDVDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: MMP7_RAT
Sequence: MAAMRLTLFRIVCLLPGCLALPLSQEAGEVTALQWEQAQNYLRKFYLHDSKTKKATSAVDKLREMQKFFGLPETGKLSPRVMEIMQKPRCGVPDVAEFSLMPNSPKWHSRTVTYRIVSYTTDLPRFLVDQIVKRALRMWSMQIPLNFKRVSWGTADIIIGFARGDHGDNFPFDGPGNTLGHAFAPGPGLGGDAHFDKDEYWTDGEDSGVNFLFVATHELGHSLGLGHSSVPSSVMYPTYQGDHSEDFSLTKDDIAGIQKLYGKRNKL
What is the function of this protein?
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin.  Activates procollagenase (By similarity).
What are the official names of this protein?
Matrilysin, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GC_VZVD
Sequence: MSKKTFPSFKFRGGCFNLLFKGSVDVSIKTRMKRIQINLILTIACIQLSTESQPTPVSITELYTSAATRKPDPAVAPTSAASRKPDPAVAPTSAASRKPDPAVAPTSAASRKPDPAVAPTSAATRKPDPAVAPTSAASRKPDPAVAPTSAATRKPDPAVAPTSAASRKPDPAANTQHSQPPFLYENIQCVHGGIQSIPYFHTFIMPCYMRLTTGQQAAFKQQQKTYEQYSLDPEGSNITRWKSLIRPDLHIEVWFTRHLIDPHRQLGNALIRMPDLPVMLYSNSADLNLINNPEIFTHAKENYVIPDVKTTSDFSVTILSMDATTEGTYIWRVVNTKTKNVISEHSITVTTYYRPNITVVGDPVLTGQTYAAYCNVSKYYPPHSVRVRWTSRFGNIGKNFITDAIQEYANGLFSYVSAVRIPQQKQMDYPPPAIQCNVLWIRDGVSNMKYSAVVTPDVYPFPNVSIGIIDGHIVCTAKCVPRGVVHFVWWVNDSPINHENSEITGVCDQNKRFVNMQSSCPTSELDGPITYSCHLDGYPKKFPPFSAVYTYDASTYATTFSVVAVIIGVISILGTLGLIAVIATLCIRCCS
What is the function of this protein?
Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.
What are the official names of this protein?
Envelope glycoprotein C, gC, Glycoprotein V, gpV.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: ZAPD_SALEP
Sequence: MHTQVLFEHPLNEKMRTWLRIEFLIQQLSINLPIADHAGALHFFRNISDLLDVFERGEVRTELLKELERQQRKLQAWVEVPGVDQDRIEALRQQLKSAGSVLISAPRIGQQLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLQQAQRDAQIESWLASLNPLTQALTLVLDLIRNSAPFRKQTSLNGFYQDNGDDADLLRLMLTLDSQLYPQISGHKSRFAIRFMPLDSENGLVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RS14_ORITI
Sequence: MAKVSSVQKNLKRSKLFNKLKLKRQALKSKIYDKNLSLEERFNLVLKLSKLPRNSSSTRIRNRCAETGRPRGYYRKFKLCRNIIRELAGSGIIPGLRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: HIS61_CAMJE
Sequence: MLTKRIIACLDVKDGRVVKGTQFKNHKDMGDIIELARYYSQNGIDELVFYDIAASARKERISREWVSEVAKNINISFCVAGGIKSEEDAAELLANGADKISINSPALNDPSLITRLAKSFGVQCVVVGIDSFKDENGNLKVFQYTGDEKTSKHSGKSTLEWVKKVQDLGAGEIVLNMMNQDGVKNGYDLEQLEAVYKICKVPLIASGGAGKMEHFLEAFKLGIDGALAASVFHQKLIDIKELKIYLKNQGLSIRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit hisF1, IGP synthase cyclase subunit, IGP synthase subunit hisF1, ImGP synthase subunit hisF1, IGPS subunit hisF1.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ2_CAEEL
Sequence: MLGAIARKTVENRILVSRHLISSTSCLFKDNNEELLESIKERIARNRRILQKHSSSHLKAREVNASISNLRQSMAAVQKKQKAAHEPPANSIVNIPSQVSIEVLGNGTGLLRACFILRTPLKTYMFNCPENACRFLWQLRIRSSSVVDLFITSANWDNIAGISSILLSKESNALSTRLHGAMNIKHFLECIRPFQDSDYGSCKYPSQVEERPYTMENYEDAGLKVTYIPLSPPLNIGSNNEKSKNVKVNNVDIAFLIEMKEAARRIDTMKLMELKVPKGPLIGKLKSGEAVTLPDGRTIQPDQVFSSDKVEGDKPLLLVTECTTEDHVKALIDSSSLQPFLNGEKQLDYMVHISDDAVINTPTYRHLMEKLNNPSITHLLINGGNPVIPAVESVYKHTRLLRSIAPSLFPALHPIDWSGIITQNEELSQRQDQFIRVAPMQRYWMRRGASFNEEPIVNNLLAAEPELSDKAKELIKEYQKLEKENKMDCEFPKLTFFGTSSAVPSKYRNVTGYLVEASENSAILIDVGEGTYGQMRAVFGEDGCKQLLVNLNCVLITHAHQDHMNGLYTIIARRKEAFESLGAPYRPLVLVCNRNVLKPMKTYSICFENIEHLLEIVDISRYPLTPPGSPGGPPGKRPRLPSPHLPPSRDVLQDMSSSFDKKAWKLDELKAVQVHHTRMANGFVMRVAGKRIVFSGDTKPCDLLVEEGKDADVLVHESTFEDGHEADAMRKRHSTMGQAVDVGKRMNAKHIILTHFSARYPKVPVLPEYLDKENIGVAMDMLRVRFDHLPLVSKLLPIFREVFVAELFELTIKKEQRVLKDKELSEKRGQLKA
What is the function of this protein?
Plays a role in mitochondrial unfolded protein response (PubMed:35451962).  Upon mitochondrial stress is exported from the nucleus where its tRNA endonuclease activity is negatively regulated (PubMed:35451962).  In response to mitochondrial stress, might be involved in activating a transcriptional response in an ATFS-1- and DVE-1-dependent manner (PubMed:35451962).  May play a role in negatively regulating the mitochondrial membrane potential (PubMed:35451962).
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 2 homolog, Homolog of ELAC2 protein, tRNA 3 endonuclease 2, tRNase Z 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: TRPR_SODGM
Sequence: MNATSSTPGAGAERLEQDWRTFARLLGQAYDDELHVPLLQLMLTPDEREALATRIRIIQALLAGDVSQRELKNELGTGIATITRGSNSLKSAPPELKRWLIQQLRDTPL
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SALRD
Sequence: MDVEIYQEDGVESGETAALDPTVFDIEPNDHIIWLDVKRIQAHQRQGTSKTKERGEVRGSGRKLYRQKGTGNARVGDAQSPIRRGGGRAHGARPRDYAHDLNQKEKRLARRSALSYKAANDNIQVIENFSLDRPDTRGLTDLFELLGVEGQDILLATAEVEREVYLSSQNLPDVNVQEVQSINTVDILDADVVLLQEGALDWLTDVLSTDEAVPA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ADA2C_RAT
Sequence: MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.