PharMolix/UniProtQA huggingface dataset:
Protein: KAD_STRP2
Sequence: MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTEMGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLAELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_NOSP7
Sequence: MGDFGNVLTAMITPFKADGSVDYGVAAELAVHLANNGTDTLVMCGTTGESPTLSWDEEYQLFVEVLQSVAGKAKVIAGCGSNSTKEAIAATQKASKIGVHGSLQVVPYYNKPPQAGLEAHFQAIAQACPDLPLLLYNVPGRTGQNLQPETVARLAEVSNIVGIKESTGSIDQASEIRRLTPKEFHIYSGDDYMTLPLLAIGAKGVVSVASHLVGNQLQQMIQAFSAGKIEVARDIHLQLFPLFKALFLTSNPIPVKKALKLQGWEVGSTRPPLCEADLEVSQKLEGVLKELSLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_NITEU
Sequence: MPLTPSSTRGIPETGAIPKHIAIIMDGNGRWARKRFLPRIAGHTQGVEAVRGTIKACIERGVSHLTIFAFSSENWRRPAEEVKLLMQLFLAALEREVTGLHENGVRFRVIGDISKFDPKIVDFVQQGEALTAGNSRLNFTVAANYGGRWDIMQAVRKMITENPDSAVTFDEPDIARHLALADAPEPDLFIRTGGECRISNFLLWQLAYTELYFTDTLWPDFDASALDEAIASYRKRERRFGRTSEQIAGQQENKNTVSNEDRV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CO6A2_HUMAN
Sequence: MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFIRWIC
What is the function of this protein?
Collagen VI acts as a cell-binding protein.
What are the official names of this protein?
Collagen alpha-2(VI) chain.
What is the protein family that this protein belongs to?
Belongs to the type VI collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Membrane; Peripheral membrane protein. Note=Recruited on membranes by CSPG4.
Protein: FIBP_DANRE
Sequence: MELDVFVGNTTVLDEDIYQLWLDGHSVSDVVRQRMDAGVLLECEASPDVLQSDTIDQFRTFQMCERLLQSPSKVANQLLFQIPSDQQAMLIERYYEFDSVFAREVLGKKLSKGTKKDLDDVSAKTGIALKSCRRQFDNFKRVFKVVEELKGPLVENIQRHFLLSDDLARDYATIVFFANSRFETGKRKLQYLSFQDFAFCAGQLISYWTVGAVDNMIEDMDVDLEKDFLHDLKDLKVLVNDKDLLDQHKSLVCGQLRGKIKVFNEMEASFKNLSRALVNIASKLTHAKDVRDLFIDLVEKFIEPCRSDKWTSGDLRLFLTHYSTSVHTLEAFRHQVIWDRYMGVIKSCILKMYHD
What is the function of this protein?
Mediates with IER2 FGF-signaling in Kupffer's vesicle ciliogenesis and in the establishment of laterality in the embryo (PubMed:19164561).  May be involved in mitogenic function of FGF1 (By similarity).
What are the official names of this protein?
Acidic fibroblast growth factor intracellular-binding protein B, aFGF intracellular-binding protein B, FGF-1 intracellular-binding protein B.
What are the subcellular locations of this protein?
Nucleus. Endomembrane system; Peripheral membrane protein.
Protein: APEM9_ARATH
Sequence: MEATDIWGEIERSESYLVCSMYEEAESLSSSILKRIFGNIDVLSDEASQGDHQFHDMLESAGMVLVQSLHGIGRTVEIVNELRDVFGEVAAIPVQVLLTGVCLQISNGSYLGVRDILEEFFRIWVYKDNHYILNDAGVSTKGFHAKNCLDIDEYMEVVELYTFGVLAKFSNDMGLAISWVEKAALPEERRQGILRRLHSLLSLKTASSFEENSKDSSYAVVNNKKSLGNEKNDEIDSFLKLSKQHEPWSLWSSHPLSLKVGNTQFSMSRGKVAVSLVGLIICYALKRKRAALIRIIRRQMESTRKAIVDFWKLAFSYQVNPLAAIQSIPSTTT
What is the function of this protein?
Involved in peroxisome biogenesis and matrix protein import (PubMed:24510720).  Required for pollen maturation and in vivo germination via its role in peroxisomal function, which partially involves jasmonic acid biosynthesis (PubMed:24510720).  Transported to peroxisomes via the interaction with PEX19-1 (PubMed:21487094).  Required for peroxisomal protein import by acting as an anchoring protein for the AAA ATPase complex, which consists of PEX1 and PEX6 (PubMed:21487094).
What are the official names of this protein?
Protein APEM9, ABERRANT PEROXISOME MORPHOLOGY 9, Protein DAYU.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: RLMKL_STRM5
Sequence: MKFFVSCAKGLEYLLADELSALGLEKATATIAGVNAEGELEQALRIVMWSRLASRVLWPIDAFECPDEQALYDGVRALPWHEHIKPEMTLAVDAHVSGDKITHARFAAQRIKDAIVDRMRDEGLERPSVNTDLPDVRVNLSLRKGRASLSIDLGGGSLHRRGWRGAAHEAPLKENLAAALLLRAQWPRLHAAGGGLLDPMCGSGTLLIEGALMAADVAPGLMRHGSLPPSRWLGFDKAAWKAIQSEARDREAAGLAALKPVIHGSDIDPTAIQAARENAEVAGVAHAIRFTRADVADLAAPEQEIGAVVCNPPYDERLAADPALYRALGNALQKAVPQWRASLLCGNDELAFATGLRAGKKYQMFNGALECALIICDPIAVPGRDPAQPRELSEGAQMVANRLRKNLKKFKSWRAREDITCFRAYDADLPEYAAAIDVYEEDGGQRRTFLHVQEYAAPAAIPENDVRRRRNELLAAAREVFGVPPEQVSMKSRERGKGGSKYGRFEQRDEFIVVRENNALLQVNLFDYLDTGLFLDHRPLRRMMAEQALGKRFLNLFCYTGVASVQAAVAGAASTTSVDLSATYLQWCYDNLALNGQGGNQHLLVQADAMAWLEGDRGQYDVIFCDPPTFSNSARADDFDVQREQLKLLRAAVARLAPGGVLYFSNNFRRFKLEENAIAEFAQCREITARTIGPDFERNARIHRAWELKRLG
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SINMW
Sequence: MNFLMDASNRTGDVLSVSDLASEESRSTATPMMEQFIEIKANNRDSLLFYRMGDFYELFFQDAVEASRALGITLTKRGQHMGQEIPMCGVPVHAADDYLQKLIALGYRVAVCEQVEDPAEAKKRGGKSVVRRDVVRLVTPGTITEDKLLSPSESNYLMALARIRSGSEPAYALAWIDISTGIFRLAETAESRLLADILRIEPRELILPDTVFHDPDLRPVFDVLGRVAVPQPAILFDSATAEGRISRYYGVGTLDGFGSFSRAELAAASAAVSYVEKTQLQERPALGIPERESAASTLFIDPATRANLELAKTLSGSRDGSLLKSLDRTVTSGGARLLAERLMSPLTDPERINRRLDSIEMLADQPRFTADARDALRRAPDMPRALSRLALGRGGPRDLGAIQAGMRAAVAIAALLSGAELSVELAEARDAIAGLPRDLLARLDATLAEELPLLKRDGGFVREGANAELDEMRALRDQSRRVVAGLQLQYCEETGIKSLKIKHNNVLGYFIEVTAGNAGAMIDTDAGRARFIHRQTMANAMRFTTTELAELETKIANAADRVLAIELETFEVMTREVVAEAEAIKAAALALATIDVSAGLAVLAEEQNYTRPAVDRSRMFAIDGGRHPVVEQALRRQAANPFVANGCDLSPPGGEEGGAIWLLTGPNMGGKSTFLRQNALIAIMAQMGSFVPASAAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQATDRSLVILDEIGRGTATFDGLSIAWAAVEHLHEVNRCRGLFATHFHELTVLSEKLGRLSNATMRVKEWDGDVIFLHEVGPGAADRSYGIQVARLAGLPASVVARARDVLAKLEDADRKNPASQLIDDLPLFQVAVRREEAARAPGLSRAEEALKALNPDDMTPREALDALYALKKQLSNR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DNAA_PASMU
Sequence: MKPDLSSLWQECLLQLQDQISLTDFSTWLRPLQADFSVQNTIVLYASNVFIKQKVDESYLAQLTKVAQELSGNAELVVQVKVGVKPEPKPAQPSALPTHHNKEENKPQTVIRSYLNPKHVFENFVEGKSNQLARAVAQKVADNPGEPSSNPLFLYGGTGLGKTHLLHAIGNGILSRNTNARVLYIHANNFMQQMVNAVRDNKMDEFKKFYRSLDALLVDDIQFFAEKEKTQEEFFHIFNNLFDTGRQIILTSDRYPKEIEKLEERLKSRFGWGLTTAIEPPELETRVAILLKKAEEKNIYLPEEVAFFIGQKLRTNVRDLEGALNRVSANAEFMGAAITIDFVRETLKDMLALQDKLVTVENIQKVVAEYYRIKVSDLKGKSRSRSIARPRQLAMALSKELTNRSLPEIGKNFGDKDHTTVLHACRKIAELREQEHSLEEDWSNLIRTLSV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD22_NEMVE
Sequence: MEEVDNIIIHTLRQIGCEIPEEIQSLREFTTTVIVQASSKCLHVINEDIDIPSNLPSSMSAKFRVGTMLAAALQDLGYRGEIGYQTFLYSNEKDIRSVFMFLVEHLPKETSLAASEPLGSSVLLNRRVASDLAQRLTLSWTPTFLKKGGVRWKGSKPKTYFREGSASMRRFHACNLKSPQGLTDLTAKISKETKAYYSVIPYVTSQPPCRQDVVPSVLESNSLSVTAVAEWELEWNQSGLSSRLTKEEYLARKRQRLEKKIKDHVLAEMQRVEAGGRAASDLSDIVSSFSDRVSTIESQTQGSRFTRTEKLQFAQDEQKAAAMAGLSESGPPKMDTEEELQKKREQELEALQNKLKDLASSVDEKKSEIKTMNAGLQQTNEQVTATKVQNSEHEESYKVKKRTVDLLPDAENNIAKLQGVVDSSSQRLVNLAQQWETHRTALIDEYRELKVINANKVSETQKKLEEIKSLREKMKEVAEETRGKDDLYKQLVSEYERMSRDVNRSAYTRRILEIVGNIKKQKEEINKILVDTKSVQKEINQLSGKLDRTFTVTDELIFRDAKKDEACRKAYKYLASLHENCKELIQAVEDTGVIMREIRDLEEQIDTESQRNTANNLERITADHKQMKEENATLTKKIKALKSS
What are the official names of this protein?
Coiled-coil domain-containing protein 22 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
Protein: MURG_CHLTB
Sequence: MKKINKIVLAVGGTGGHIIPALAARETFIHEDIEVLLLGKGLAHFLGDDSEIAYCDIPSGSPFSLRVNRMFSGAKQLYKGYVAALQKIRDFTPDLAIGFGSYHSLPAMLASIRSRIPLFLHEQNIVPGKVNKLFSRFAKGVGMSFAAAGEHFHCRAEEVFLPIRKLSEQIVFPGASPVICVVGGSQGAKILNDVVPKALARIRESYSNLYVHHIVGPKGDLQAVSQVYQDAGINHTVTAFDHNMLGVLQASDLVISRSGATMLNELLWVQVPAILIPYPGAYGHQEVNAKFFTHTVGGGTMILQKYLTEESLSKQVLLALDPATSENRRKAMLSAQQKKSFKSLYQFICESL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VPC48_MYCTU
Sequence: MSETFDVDVLVHATHRASPFHDKAKTLVERFLAGPGLVYLLWPVALGYLRVVTHPTLLGAPLAPEVAVENIEQFTSRPHVRQVGEANGFWPVYRRVADPVKPRGNLVPDAHLVALMRHHGIATIWSHDRDFRKFEGIRIRDPFSG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB48.
What are the official names of this protein?
Ribonuclease VapC48, RNase VapC48, Toxin VapC48.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: ALBU_MOUSE
Sequence: MKWVTFLLLLFVSGSAFSRGVFRREAHKSEIAHRYNDLGEQHFKGLVLIAFSQYLQKCSYDEHAKLVQEVTDFAKTCVADESAANCDKSLHTLFGDKLCAIPNLRENYGELADCCTKQEPERNECFLQHKDDNPSLPPFERPEAEAMCTSFKENPTTFMGHYLHEVARRHPYFYAPELLYYAEQYNEILTQCCAEADKESCLTPKLDGVKEKALVSSVRQRMKCSSMQKFGERAFKAWAVARLSQTFPNADFAEITKLATDLTKVNKECCHGDLLECADDRAELAKYMCENQATISSKLQTCCDKPLLKKAHCLSEVEHDTMPADLPAIAADFVEDQEVCKNYAEAKDVFLGTFLYEYSRRHPDYSVSLLLRLAKKYEATLEKCCAEANPPACYGTVLAEFQPLVEEPKNLVKTNCDLYEKLGEYGFQNAILVRYTQKAPQVSTPTLVEAARNLGRVGTKCCTLPEDQRLPCVEDYLSAILNRVCLLHEKTPVSEHVTKCCSGSLVERRPCFSALTVDETYVPKEFKAETFTFHSDICTLPEKEKQIKKQTALAELVKHKPKATAEQLKTVMDDFAQFLDTCCKAADKDTCFSTEGPNLVTRCKDALA
What is the function of this protein?
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.  Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).  The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity).  The rank order of affinity is zinc > calcium > magnesium (By similarity).  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E. coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E. coli (By similarity).  Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
What are the official names of this protein?
Albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: IQAK1_MOUSE
Sequence: MSTKKGGPKAASGKGQALLPGSKLRATAGKPRESRQLQRKASHPSKGSFSENPQAPAAPTAEDKAAIVIQCAFRQYLARRELARRCQERQEYLDEMEKLQKEAYLALVRQEQEAARRQREKEEAEERARREELQRRRRLLEAAFEGDLGEIRQVLKEVEQLMTREGVGYDEDGKARRLQRRVATVECEDSHGNTPLSEAAAGGQTMAIQLLAELGANPNTKGAFGRTPLYRAAFGGHLEAVEELLKIGADPRMYADDGSTPEQVASLAAVASVLQSWDLSLTEAMLKNMEAEQQRRAQEAQKHKENEAKRINIKVQQLAKEQQKCQKELQQAYCELNRRIMEHDKCERKFMGNTELTLQAIKDAEAQVDRLQQEAQKAEETLAMARLELREQTPEDEDTEPGLKCRVTELHDVLMKDVGDRIRADGRWPLVIDPSGQAATFLRYQDTNYVDTLNPEHLRPERIRLALLGALRYGKPLVFDLRQVNLFPVVQQQLEVVQTGLAQALLNRGLLAKEGYLSLLRPTDGPEYDPSQFQEARLEN
What are the official names of this protein?
IQ motif and ankyrin repeat domain-containing protein 1.
Protein: PRAME_HUMAN
Sequence: MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMPN
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:21822215, PubMed:26138980).  The CRL2(PRAME) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding (PubMed:26138980).  In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin regulation (PubMed:21822215).  Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG: prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis (PubMed:16179254).
What are the official names of this protein?
Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Golgi apparatus. Cell membrane. Note=Associates with chromatin; specifically enriched at transcriptionally active promoters that are also bound by nuclear transcription factor Y (composed of NFYA, NFYB and NFYC) and at enhancers (PubMed:21822215). Recruited to the Golgi apparatus in response to interferon gamma (IFNG) treatment (PubMed:23460923).
Protein: VATI_DEIRA
Sequence: MISPMQQVVIAVRKRESDNVITALQDAGVLHLRPIAEGPLSTGNLAGQDAQERREDERLLARAESTIAELGAYRPAPAPLPAQSEWETVVEGAAQPVSHLAKRRQELQSDLEVDRTYGDAVRALARMVGTLDRSRRVALVPFLIGATENLGELDGALRESLGDRYTVASEVVGANRVGVIATLSADRDAARAALSKARLGELRLPGRFDTMPLGAAADELGRVRQGGDDMQRALNAERDRLAQQHGPALYAVRDALKDRVAVHDVRAVSARGKYSLAMQGYVPADRIPALQSTLSRFGDAVSYEVFPVDEHHDQDVPVELKNSGYVTPFQNTVMGLMSLPKYGSFDPTWVVALFVPLFFGIIMADIGYGLLFLAFGMWLLGKARRNEGWDLSLFGAYLPPATLRDLGFVTNVMAGWTILWGFLTGEFFGTLFEHLGVFYMNNDLLNRLWGWTGVHWGAHAAEGGHSTGLLPIVFPRLDTENFGNIALVFALCFGILQVLWGWGIRVQQGLKHNDQAHVWEGLAMFGGVGALILLGFISKAGADFGALSNFGDWRVLLMILGFVLFIVGYLRVAKQFPLLPVELVSQGGSVVSYARIFAVGLVSAILAKLCTDLGWSLSQQIGFLGIILGIVIGALLHFFVLALTLIGHILQPIRLHMVEFLNPTGFNNETSPRYAPLRRLSPASDAGQVK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPC_THEFY
Sequence: MSVLDEIIDGVRADLAERQAAVPLDKLKEQAAALPWPKDVVAALRAPGVQVIAEVKRSSPSKGALAAIADPAALARDYAAGGACMISVLTEQRRFAGSLADLAAVRAAVDTPLLRKDFVVSSYQLWEARVYGADAVLLIVAALSQDALVSLVERAESLGLTPLVEVHTEEEVERALDAGATVIGVNARDLKTLKVDRGTFARLAPLIPDDKIKIAESGVRGPHDLLAYASAGADAVLVGESLVIGRKPREAVADLVTAGAHPALRDRH
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: BPT_RHOPA
Sequence: MTQHSRDTPQFYLTAPSPCPYLPGRHERKVFTHLVGNKAGELNDLLTHGGFRRSQSIAYRPACDQCRACVSVRVIANEFKPSRNQRKLLARNADIVGEQRNPVPTSEQYSVFRAYLDQRHRYGGMADMTVLDYAMMVEDSHVQTRMIEYRKRTPDTGITGRGGELIAAALTDVLGDGLSMVYSFYEPNEQHRSLGTFMILDHIARARRLGLPYVYLGYWIEGSKKMDYKGRYLPQQRLAPSGWLRIDASGEMQPEPQD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2223_BURCH
Sequence: MIIVLSPAKSLDYETPAHVESYTKPAFVDDASELIDGLRKLSPQDIATLMDISDPLARLNFQRYADWSPTFTPANAKQAVLAFNGDVYEGFDAKSLSSTDLDYAQQHVRVLSGLYGLLRPLDLLQPYRLEMGTRFANARGKDLYAFWGDRITRALNEQLETRSGAARVLVNCASTEYFKSVKPKLLAAPVITPVFEDWKGGRYKIISFHAKRARGLMARFVVENRITDPNALKEFATEGYAFDAAASNDSTYVYRRRVGE
What are the official names of this protein?
UPF0246 protein Bcen2424_2223.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: TIM22_ASPOR
Sequence: MNIPGMTTGMAPAGATAGAGFPGAGAGMQGMSEQEQAMVKAMHAAMESCPVKTVISGTMGFGLGGVFGLFMASMSYDSTFTPQGKAIMDLPWREQVRRGFKDMGSRSWSSAKNFGIVGALYSGTECCVEGLRAKNDLSNSVISGCITGGILGAKAGPQAAAAGCAGFAAFSAAIDAYMRMPSEE
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KTHY_VACCT
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPANTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVTFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SMIM4_DROME
Sequence: MSPYSGSVRRLLDSWPGKKRFGVYRFLPLFFLLGAGLEFSMINWTVGETNFYRTFKRRQAKNYVEEQQHLQARAANNTN
What are the official names of this protein?
Small integral membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the SMIM4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL27_RHOPS
Sequence: MAHKKAGGSSRNGRDSAGKRLGIKAYGGEYVIPGNIIARQRGTTWHPGLNVGMGTDHTLFAKVEGRVEFRAKANGRTFVSVLPIAAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FMT_BOVIN
Sequence: MRVLLRCCCGHLPVGGGAGRRSNPRWRALARLSASPGWEDGQGARVREKPPWRVLFFGNDQFARETLRALHAARENKEEELIEKLEVVTVPSPSPKGLPVKQYAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEAFILKFPYGILNVHPSCLPRWRGPAPIIHTILHGDTIAGVTIMQIKPRRFDVGPILKQETVPVPPKSTSKELEAVLSRLGANMLISVLKNLPESLNNGRQQPAEGVTHAPKISAATSCIKWEEQTSEQIFRLYRAVGNIIPLQTLWMDNTIKLLDLVEVDNSILSDSKLTGQAVIPGSVIYHKQSQILLVCCKDDWIGVRSVMLKKTLTATDFYNGYLHPWYQKNSQAQPSQCRFQTLRLPPKKKQKKKIVAMQ
What is the function of this protein?
Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.
What are the official names of this protein?
Methionyl-tRNA formyltransferase, mitochondrial, MtFMT.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEXA_SHEHH
Sequence: MRPLTPRQAEILELIKRNIADTGMPPTRAEIARRLGFKSANAAEEHLKALAKKGCIEIMPGTSRGIKLTQENTEDADLGLPLIGQVAAGEPILAQEHVEQHYKVDPAMFKPSADFLLRVRGDSMKNIGILEGDLLAVHKIQQARNGQIVVARVEDDVTVKRFEKKGNKVFLHAENEEYSPIEVDLANQSLSIEGLAVGVIRNGDWQ
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ATPE_LISMF
Sequence: MGSLNVSIVTPDGPVYEGVAQMVIARTKAGELGILPGHVPLVAPLKIDIVRLKVESGEEWVAVNGGFMEVNGEEVNILADTAEREQDIDIDRAEKAKQRAEEELSRAKEQKVDEVMAQLALQRAINRIHAKEHN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.