PharMolix/UniProtQA huggingface dataset:
Protein: NUSB_BARQU
Sequence: MADIKGKYSPRLANKRGAARLAAVQALYQMDIVGSGVMETAAEYEAYHLEKNIDGNQYLDADFQWFLAIITGVVKDQKQLDPMLHQQLSAEWSLSRLDSILRAILRAGLWELINRQDVPIAVVMNEYVDIAKAFFEGDEPKLVNAVLDSMAKKIRL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ATPA_PSEA7
Sequence: MQQLNPSEISEIIKGRIEKLDVASQARNEGTIVSVSDGIVRIYGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGEYQGLAEGMNAKCTGRILEVPVGPELLGRVVDALGNPIDGKGPIDAKATDAVEKVAPGVIWRKSVDQPVQTGYKSVDAMIPVGRGQRELIIGDRQIGKTALAVDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEENGALANTIVVAASASESAALQYLAPYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIAEMSLSLYAAERGFLQDVEIAKVGSFEQALISYFQREHAALLAKINEKGDFNDEIDAGIKAGIEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DEF_EDWI9
Sequence: MAVLQVLHFPDERLRTIAKPVHEVTPEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDQRLVLINPELLQHDGEAGIEEGCLSVPEQRALVTRAENIKVRALDRDGKSFELETDGLLAICIQHEMDHLMGKLFIDYLSPLKRQRIRQKLEKLYKQQARAVN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: AIM3_YEAS7
Sequence: MGFWENNKDSITSGLKSAGKYGYQGTKYVAKTGYKASKKHYNNSKARRERKSGKKNSSDEEYESEDEMEYERKPTDIRSLKDPKSFPPPPLKPGQKTYAGQQQQQMPNGQASYAFQGAYQGQPGAGSMEQSQYAQPQYNQYPQQQLQQGVVPQQPPIYGEQVPPYGSNSNATSYQSLPQQNQPQYAIPSQVSLNSASQQSTGFVSQNLQYGTQSSNPAPSPSFQNGLQCHQQPQYVSHGSTNLGQSQFPSGQQQQPTTQFGQQVLPSPAQPHPQPQQQQQGQPLPPPRGQVILPAPGEPLSNGFEQQQQQQQQQQQQQPLNQNNALLPQMNVEGVSGMAAVQPVYGQAMSSTTNMQDSNPSYGASPMQGQPPVGGQPPVPVRMQPQPPQPMQQGNIYPIEPSLDSTSSTPHFEVTPFDPDAPAPKPKIDIPTVDVSSLPPPPTHRDRGAVLHQEPAPSGKIQPNTTSSAASLPAKHSRTTTADNERNSGNKENDESTSKSSILGHYDVDVNIMPPPKPFRHGLDSVPSEHTRKNALERAVPILPPRNNVEPPPPPSRGNFERTELVLSTNAANVQEDPISNFLPPPKPFRHTETKQNQNSKASPVEIKDEVLPGHPSEEDRNVEPSLLPQSKPQSKSQSQFRRAHMETQPIQNFQPPPKPFRRSQSSNSSDSSYTIDGPEANHGRGRGRIAKHHDGDEYNPKSENSTENGRLGDAPNSFIRKRAPTPPAPSRSEKLHEGAITSEFDSSKDANKYEKSIPPVTSSIQAQQSTKKAPPPVVKPKPRNFSLKANEYPKELTREATGQDEVLNSITNELSHIKLRKTNVNLEKLGGAKKVKDSSPVPSDLDEKYVSASGSITPPRPPPSRSSPKKVPPVVPKKNDNLKKKPPVVPKKKPLLKSLEPRPIEMERAYSGDISAADDNLNPFERYKRNVVPQEDDRLHKLK
What are the official names of this protein?
Altered inheritance of mitochondria protein 3.
What is the protein family that this protein belongs to?
Belongs to the AIM3 family.
What are the subcellular locations of this protein?
Membrane raft; Peripheral membrane protein. Note=Localizes within detergent-insoluble glycolipid-enriched membranes.
Protein: DEOB_LEGPH
Sequence: MTGRVCVLVMDSFGIGASLDAARYGDAGANTLVHIYEACKRGECDIEGVRKGPLMLPNLAGKGLYHAAMASSGLSFIDLATLAIPSGYYGYAVEQSLGKDTPSGHWEMAGVPVTFEWGYFPDKPYCFPEELISEFIKQCNLPGVLGEKHASGTIIIDELGEKHIRTGKPIVYTSADSVFQIAAHEEAFGLQRLYDICKIARNLVDKYQIGRVIARPFTGKPGSFKRTGNRKDYATPPPEKTLLDFLKEDGREVIAIGKIADIYAHQGVTQEIKADGNMALFDATLSAMKTAPQGSLVFTNFVDFDSSYGHRRDIAGYAHALEQFDARLPELDALLQPDDMVFIAADHGCDPTFPGSDHTREHIPVLVFGPQVNSKFIGRRDCFADIGQSIAEHLQLSSPLAHGVSFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCDC9_MOUSE
Sequence: MATTLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKSRSMEKENMAVEEKSLGPSRRTPGTPRPPGASRGGRTHPQQGGRAGVGRASQGWEDGAGEQLRGGPGGRGRRGRGRGSPHLLGAGDNSTSDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRGGPLEESERDRREGSRRHGRNWGGSDFERVRSGLEQERQGRRAGLGSGGDMTMSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAPTHELSHRYDDQAWARPPKPPTFGEFLSQHKAEVSSRRRRKNSRPQAKVAPRAYSDHDNRWETREEAVSSAPESSQSISLEETPTQASETPAPAHRPPEEDGEEDVGEEEEGEEEGEDEEDEEWEDVSEDVTEEEEEEEEEFEEDEEGPKDQEAATVPDHQPEAEPAGKPTCEQVDPVPAGSQELLSPVPVEPPIPFSPSEDHQPVSDWGEEMELNSPGTAHLPGTHSSGEAWPFANA
What is the function of this protein?
Probable component of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
What are the official names of this protein?
Coiled-coil domain-containing protein 9.
Protein: G1PDH_METM5
Sequence: MIVIPRYTIIKEKASSRIPEILDNLNLKNPLVITGKNTKKYNKDFDFIYYDEIETSDLENIKNYANDYDSIMGIGGGRPIDIGKLIAHKSKKPFLSVPTTASNDGIASPIVSLTQPSYMTEAPIAIIADIGIIKKSPKKLLSAGMGDIVSNITAVLDWELGKIEKSEKYSDSSGIFSKTIAIELMDYVLNSNLEEYPKKLVKALIGSGISIAIAHSSRPASGSEHLFSHALDIMKEKYDIDTDSLHGEQCGVGTLAIAQIYFEEKKLDIETFEMIKKSLKAVDAPITAKQLGFDDEIVIEALSSAHALRNRHTILRNGISKTEARKILEKSEII
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y538_CHLPD
Sequence: MSGHSKWATIKRKKAATDQKRGNLFTKLVKEITIAAKMGGADPGGNPRLRLAIDTARSNSMPMENILRAVKKGTGELEGVTYDEITYEGYGPAGIALIIETATDNRNRTVADIRHIMSRNNGSLGESGSVSWMFHRKGSLDVSKSAVSEDMLLEILLDAGLEDLESDDAIYYTVITDLKDLETVKKALDAAAIPFENARIDMIPENYIELEAEDASKVIRIIDALENNDDVQAVYSNMEISEKAMNSLNE
What are the official names of this protein?
Probable transcriptional regulatory protein Cpha266_0538.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_GOSHI
Sequence: MLSPKRNRFRKQHRGRMKGISYRGNRICFGRYALQALEPAWITSRQIEAGRRAMTRNVRRGGKIWVRIFPDKPVTVRPTETRMGSGKGSPEYWVAVVKPGRILYEMSGVAENIARKAISIAASKMPIKTQFIISG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FENR_PEDPA
Sequence: MTEMYDITIIGGGPAGLFAGFYAGMRTAKTQIIESLPQAGGQVAALYPEKMIYDVGGYAGIKAANLAKELEKQTRLVGTEIRLNETVVDIQAQADFYHVKTNRNEYDTRAILLATGNGAFNPRKLAVEGLDHLEDKKIYYHMPDVEHFENQDILVAGGGDSAIDIALMLEPIAKSISLVHRRQQFRGMERNVQHLQESTVKVMTPYLINGVREAVEGIDVDLKEIGTEALKATHFDKLIVNYGFTSSNKIIKGWEIDLTQEHRMFAVDSLMHTNMKNIYAIGDGVEYPGKLRLIATAFGEGPIAVNQIMNDLYPGKRGPVHSTSMFEK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: Y2216_METBU
Sequence: MADLIGLAIVFLIFALVAYVLGARGVAGLSMTIAKWLVIIFIVLAIITILL
What are the official names of this protein?
UPF0391 membrane protein Mbur_2216.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURU_ECOL6
Sequence: MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTIIL
What is the function of this protein?
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
What are the official names of this protein?
Formyltetrahydrofolate deformylase, Formyl-FH(4) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
Protein: ROMO1_PIG
Sequence: MPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGPFSCLRIGMRGRELMGGIGKTMMQSGGTFGPFMAIGMGIRC
What is the function of this protein?
Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation.  May play a role in inducing oxidative DNA damage and replicative senescence.  May play a role in the coordination of mitochondrial morphology and cell proliferation (By similarity).
What are the official names of this protein?
Reactive oxygen species modulator 1, ROS modulator 1, Protein MGR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MGR2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SLYX_PSEU2
Sequence: MSLEERVMELESRMAFQDDTIQALNDVLVKQRRELDHLQLQMAAMLKRQEEMGSQFETFEEDAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: KGUA_SODGM
Sequence: MIQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAMRPGEAHGQHYFFVPVAEFEHMIAEDAFLEYARVFDNYYGTSREAIQQVLATGVDVFLDIDWQGAQQIRAKMPDARSIFVLPPSKEELDRRLRGRDQDSEEVIGRRMAQAVAEMTHFAEYDYLIVNDDFNTALLDLKTIIRAERLRLGRQKLHHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_HALS3
Sequence: MTLEVTFLGTSGAVPTTERNPSSVFVRRNGDAFLFDAGEATQRQMMRYKTGFGVSDVFITHGHGDHVFGLPGLVHTWDFNDRTDPLTIHVPRGLRGDIEDLVFSAGGDVGYPVRITEATPGAVVRSHDDYEVRAFETAHSTASVGYALVEDDRTGRFDRARAEELGVPVGPKFSTLHDGQPVELDDGTVVSPEQVVGDPRPGRTLVYTGDTRPHDPVVSAAEDADLLIHDATFANDASERAAETGHSTAGEAADVATEAGAKALALTHVSSRYAGDASEISAGASGFDGEAFVAHDGLTHEIPFPDAD
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ACCA_PROM9
Sequence: MAKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLATRRREEIFKSLTPAQKIQVARHPQRPSTLDFVQMFCDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHADRFSLPILTFIDTPGAYAGLTAEEQGQGEAIARNLREMFGLTVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAKAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLDTLLQMTKDELIEERYKKFRVLGKFIEANNIEEIYSEIPPQSE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_MYCS2
Sequence: MTGFGQRLDAAVSARGPLCPGIDPHPELLNAWGLTVDAEGLRAFCDICVAAFAGFAIVKPQVAFFEAYGSAGFAVLEDTIAALRAEGVLVLADAKRGDIGSTMAAYAAAWAGDSPLAADAVTASPYLGFGSLRPLLDTAVANGRGVFVLAATSNPEGVGLQRAVAGDVTVAQSIVDAVAQANREADPAARDGDPVGPFGVVVGATVADPPDLHMLGGPVLVPGVGAQGGRPEALGGLGNARRLLPAVSREVLRAGPAVDDVRAAAERLRDQVAYLA
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: RL22_UREP2
Sequence: MTNKVIQRNIHISHRKASLVIDLVRNKPVHEAIRILSNTPKKFAPIVLKLLNSAISNVQHNSKDMDPSKLYIYKIVANQGPTMKRTLPRAKGSADQLFKRTTHLEIVLSDDVNEREKELAAIKAKKSKKPLAVEPIAKVETKKVAKPSKVEIKPVEKDENVDPELLKREQQVLKVVEKTASQKEEETTETIMISTSPKNAQVLFDDLEKNVIFYKTTPINKVLRVLVYVTSPTKKVVGEFDLESVEIGAISSIWRKYSKQSVISKKEYDAYYEGKDKAHALVSKKAYKYRNPKDLSEYNMTKGPSGFQYLK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TRUA_COXB2
Sequence: MARIALGIRYDGSAYHGWQVQEALKTVQGEVEKALSAVANHPVFVTCAGRTDAGVHASAQVAHFDTTAYRSDHAWVFGANSNLPHDISILWAKAVEEDFHARYSAMARRYRYIVYNHEIRPAILRKAIGWHYRPLDEKRMQAGAQYLIGEHDFSSFQGAGCQSRTPVRKIFQIEIYRIRRMVVIEVQANAFLLHMVRNIAGVLIAIGSGEKHPDWAQTVLKAKDRRQGGVTVPPNGLYLVEVNYPPNFKLPRMPLGPFFLP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YWTE_BACSU
Sequence: MKCIAIDLDGTLLNKESVISAENREAIKRAVDAGILVTICTGRATFDVKALLDDLDIPIIAANGGTIHDTGYRLISRTLMDQEAGKAIADYLLSKNIYFEVYTDDHLLSPFDGEAKLHAELDILKSANPNEQTDDLWQGAMTQFKQFGIKPIPHIESVFDGGENIYKLLCFSFDMDKLKQAKEELKHHKKLAQTSSGKHIIEILPASSGKGRALTKLADIYGIETQDIYAIGDSPNDLSMFEVAGHRIAMENAIDELKEKSTFVTKSNDENGVAYFIDQLLSGQYA
What is the function of this protein?
Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro (PubMed:26316208).  Also catalyzes the dephosphorylation of phosphorylated 5-6 carbon sugars and monophosphate nucleotides (NMP) in vitro (PubMed:25848029).
What are the official names of this protein?
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YwtE.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: CHEA_BORBU
Sequence: MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASLDMMELSDFTHIVEDVFDAIRDGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISDLKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIREGLGIGQKVLRISVVFNSNSNSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLNLIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFKVRLDFVKDNPMATISGLQMLQALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEESIAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKENKNIKKNSPISVNLIRIDSKKIDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLTLEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTRMLPISNIFSRFTRVVRDLSKKLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHGLETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGIDPKVIRRKLIEKGTIKEDAIYSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIKLPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRLDKLFNITRDDSLIEKFLIVVNTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATTLGNGKVVLIIDVFKLFDLQKDTKE
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
What are the official names of this protein?
Chemotaxis protein CheA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_TRYCC
Sequence: MGILGLSKLLYDRSPAAIRERELKNYFGRRIAIDASMTIYQFIIAMKGFQDGQGMELTNEAGEVTSHLNGLFARTLRMVDEGLRPIYVFDGKPPTLKASELQERRQRAEEAQQLFDTAKEEGNDELMEKMSKRTVRVSREQLEEAKKLLQLMGIPVVQAPSEAEAQCAELVKKKKAWAVATEDMDALTFGAPVMLRHLTYSEAKKRPIAEFHLDEILGITGLTMTQFIDLCILLGCDYVPKIPGIGPQKAWEGIKKHGDIETLLQSLDAGRHSVPEGFHYEEARQFFLKPEVTPAEEIEIQFREPDEEGLVKFLVEEKLFNKDRVLKGIQRLRNALTRKTQGRLDQFFTITRPVTKPNTCDAKAGVKRGHSAIALSGTLQQKGSSGHKKVVKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: GATA_RHILW
Sequence: MSELTSLTIAEARRKLRAKEITALELTEAYISAIDAANGHLNAYIKVTPDLARLMAKNSDERIAAGKAGDLEGIPLGIKDLFATVGVHTQACSHILDGFEPRYESTVTQNLWDDGAVMLGKLNMDEFAMGSSNETSHYGAVINPWRAAGSNQQLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGTVAFASSLDQAGPIARDVRDAAILLKSMASVDAKDTTSVDLPVPDYEAALGQSLKGMKIGIPSEYRVDGMPEEIETLWRQGIAWLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVDGKDIVDMYEKTRAAGFGKEVKRRIMIGTYVLSAGYYDAYYIRAQKVRTLIKRDFELAFNAGVDAILTPATPSSAFGVADENLASDPVKMYLNDIFTVTVNMAGLPGIAVPAGLDQKGLPLGLQLIGKPFDEETLFKTAHVIEQAAGRFTPARWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PRIS_METAR
Sequence: MNDQTRAFLRERFRDYYSRSKVFVPPGLAQREWGFIFHEETVGVAMRRHKAFNSEGELADYLRSMPPAHAYHSAAYYRHPQAPTMQEKDWLGADLIFDLDADHLPGVKNMTYGEMLDNVKVEIIRLIDEFLIDDLGFREKDMDIVFSGGRGYHVHVRDERVRTLKSPERREIVDYLLGTGLEPDRMFIRTNQRIDTGTTSVAGVWLIRGFDSVPGGWDRRVARHIVEKLDQIGRLPDKDAKEALRAFSLESKDVKRILHVARDPASLQKIREKGLIELSGNLEGFFRSILAGTIDQFKVSLAGKTDEPVTADIKRLIRLPGSIHGGSSFRVTPLTRAQLESFNPLEDAIIFSDDPVRVLVTRPAVVEMKGKIYRVSEGVGRLPENVAMFLMCRGSADYEP
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: RECF_PSEPK
Sequence: MSLRRIMVTAVRNLHPVTLLPSPRINILYGANGSGKTSVLEAVHLLGLARSFRSTRLNPVIQYEQAACTVFGEVQLTEGGTSNLGVSRERQGEFTIRIDGQNARSAAQLAELLPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFLPAWQRLQKALRQRNSWLRHGTLDPASQAAWDRELCLASAEIDEYRRNYIKALKPVFERTLSELVELDGLTLSYYRGWDKDRELQEVLASSLLRDQQMGHTQAGPQRADLRLRLAGNNAADILSRGQQKLVVCALRIAQGHLVSQARRGHCIYLVDDLPSELDDQHRRALCRLLEELRCQVFITCVDHELLREGWQTETPVALFHVEQGRITQTHDHRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_DEHM1
Sequence: MEKNKTRIGHVISDRMEKTIVVGIDVAKRHPLYKKTYRRTMKYLVHDEKNEAKIGDMIEIVKCRPISKGKYWRLNRIITKGHIVAA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MATK_LILMI
Sequence: MEEFQGYLKKDRSLQQHFLYPLLLQEYIYTLAHDDSLNGSIFYEPIEFIGYDNKFSLVLVKRLITRMYQQNFLIYLVNDSNQNRFGGHTNYFYSHFFYSKMVSKGFSVIVEIPFSLRLVSSSEEKEIPKSQNLGSIHSIFPFLEDKLSHLNNVSDILIPHPIHFEILVQILQCWIQDVPSLHLLRFFLHKYQNLNKTIQSNKTIYVFSKENKRLFWFLYNSYVSECEFLLVFFHKQSCYLRSTSSGAFLERSHFYGKMEHIIIVCCNNFQKTLWPVKDPLIHYVRYQGKAILASRGTHLLMKKWRYYFVNFWQYYFHFWSQPYRMHINSLLNYSFYFMGYLLRVLINPYAVKNQMLENSFLIDTVIKKFDTIIPIIPLIGSLSKAKFCTFSGHPISKPIWADFSDFDIIDRFGRICRNLSHYHNGSSKKQSLYRIKYILRLSCARTLACKHKSTARALLQRLGSGLLEEFFTEEEQVLSFIFPKTTLFTLHGSHRERIWSLDIIRINDLVNN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATOH1_MOUSE
Sequence: MSRLLHAEEWAEVKELGDHHRHPQPHHVPPLTPQPPATLQARDLPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPRDEADSQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPNVGEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVQEDNSKTSPRSHRSDGEFSPHSHYSDSDEAS
What is the function of this protein?
Transcriptional regulator.  Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1.  Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
What are the official names of this protein?
Transcription factor Atoh1, Atonal bHLH transcription factor 1, Helix-loop-helix protein mATH-1, mATH1, Protein atonal homolog 1.
Protein: RT12_BIGNA
Sequence: MATSNQMGANTRSKKKKKNLKKALLGCPQKRGVCMRLLTRSPKKPNSAQRRVAKVRLSTKRVIFAHIPGEGHNLSPFSVVLVRGGNVRDLPGVRYKTIRGVKDLAPVLSRTNGRSKYGTKRPKVHT
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.