PharMolix/UniProtQA huggingface dataset:
Protein: ADDB_STAAB
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKCADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQSYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGYHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVVIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNLPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNINIDDEFGGEQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: Y1017_HAEIN
Sequence: MCQYFLKKIRNVWERWFTYRLWFGLSMVSIAVIFGPLTGAHVNPAVTIDFWEVGKFPTELVLVYIIAQCIGAFIVALIVWLLFKDHLDEEDNQNCQLGSFATIATNSNNLRNLLSEIVTTFSLLFILFTLNHQQPTNGVAMFFVFTGVAGGVMSFGGLTSYAINPARDFMLRLIHAIMPIKNKGTSNFDYAWVPVLRPVIGAILAAWLYKALF
What are the official names of this protein?
Uncharacterized aquaporin-like protein HI_1017.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIAR_BACSU
Sequence: MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIVLTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCLIAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN
What is the function of this protein?
Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin).  Seems also involved in response to cationic antimicrobial peptides and secretion stress.  LiaR regulates the transcription of the liaIHGFSR operon.
What are the official names of this protein?
Transcriptional regulatory protein LiaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_CLOAB
Sequence: MKEFDEMAKTYDPKEFEDRIYKWWEEEGFFTPKVDKNKKPYTIMMPPPNITGKLHLGHALDCALQDFMIRAKRMQGYEALWLPGQDHASIATEVRVEKEILKEGLNKKEMGREKFLERVWDWTKEYRERIKGQQKKLGVSADFTRESFTMDEKLNKAVRTVFVKLYEDGLIYQGNRITNWCPKCQTALSDAEIEYKEDQGFFWHIKYPVEGEDSFIEIATTRPETMLGDTAVAVNPKDERYKEFIGKLLVLPLLGRKIPVVADDYVDMEFGTGAVKITPAHDPNDYEVGKRHDLKEIVMLNNDGTIKEGFGKYSGMDRYEARKAIVSDLKEEGYLVKIKEHVHNVGTHDRCGNIIEPMVSKQWYVKMESLAKPAIEAVKAGKTKFVPERFDKIYFNWMENIQDWCISRQLWWGHRIPVWYCKDCGEIIVSEKEPKACSKCNSENLEQDKDVLDTWFSSALWPFSTLGWPDKNEDLEYFYPTDTLVTGYDIIFFWVARMVFSGIYNMGEVPFKHVYIHGLVRDAEGRKMSKSLGNGVDPLDVIDTFGADALRFMLITGNAPGNDIRYKTEKVEAARNFANKIWNASRFVLMNLDKEIMDKYKDLEEYSLADRWILSRCNSLVREVTDNIEKFELGIASQKVYDFMWNEFCDWYIELVKPVMYGEDEKAKGIAYNVLYKVLTVGLQLLHPVMPYITEEIYQHLGGEYKAIAISAWPTYEEKLKNETSENAMNQIIEAIKSIRNVRAEMNVPPSKKAKVMIFTEAENKAAFEMGEHYFEKLAYASSVSFLKSKDEAPENAVSSVTKGAELFMPLLDLIDVTKEIERLSKEKDKLKAEIQRVDKKLSNKGFVDKAPESVVEAERVKGEKYKKMLEAVEERIAALK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFRA_STAAC
Sequence: MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
What is the function of this protein?
Reduces FMN, organic nitro compounds and disulfide DTNB.  Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity).
What are the official names of this protein?
NADPH-dependent oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: STKLA_ARATH
Sequence: MSRRFNPLEDPPSASSSDEEGKEIARNSSSDDEDDVSSENPSPLKTTLDAVSDSESGSDEETDSDSELEKKKDQVVTNPVDVKRAKKVKTSEKSGAKRSLEVDEAAVSMDVKRAKKVSGEEEKKKSGGGGEETKKTYFQRLWTEDDEIVVLQGLIDDKKDTGVSNTNKVYELVKKSISFDVSKNQLMEKLRALKKKYENNLGKAKDGVEPTFVKPHDRKAFELSKLVWGGIRMALASGMKSNEKSKKSSKFESVKHELDSSLPNSKNNCEDEVMDEGEVSFTKSSLVRSIVGLGMDELTAQQGLSKLASKDMKRFYEQWKAMQAREFEFFLQKHGFLFEVLSKISEAFGSNA
What are the official names of this protein?
Probable transcription factor At1g11510, Storekeeper-like protein At1g11510.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: DEOB_BACAC
Sequence: MNKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLHMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTSADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKVVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFEKLKEDDLLLITADHGNDPVHHGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNELKK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ID1_MOUSE
Sequence: MKVASGSAAAAAGPSCSLKAGRTAGEVVLGLSEQSVAISRCAGTRLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTTGGRGLPVRAPLSTLNGEISALAAEVRSESEYYIILQWETEATGGGCPPSLLFRRIAI
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.  Inhibits skeletal muscle and cardiac myocyte differentiation.  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.
What are the official names of this protein?
DNA-binding protein inhibitor ID-1, Inhibitor of DNA binding 1, Inhibitor of differentiation 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDTD_SALPA
Sequence: MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLFHAKKSSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCP4_PINMG
Sequence: MNLLVFFVYLXVCVIGSHSIXGSQQLSTKKCGGAICAMACTYGFVLDKDGCPICKCRDAPCPLVKCLPCKYGYVIDDNGCQTCECKPLDCGLVCLIYCPYGNIPDERGCPTCFCRPRPCKELECEKKCRNNVLDEIGCPTCKCKECLEPKKVGPCRALIPRYFYDVWSGKCKKFYWGGCQANGNNFKRKSQCCKRCKS
What are the official names of this protein?
BPTI/Kunitz domain-containing protein 4, Nacre serine protease inhibitor 3, NSPI3.
What are the subcellular locations of this protein?
Secreted.
Protein: GPI14_DEBHA
Sequence: MLQLSISHIIVLSLLIRIGFFLFGLYQDKYMTVKYTDIDYVVFSDAANYVYNGYSPYSRETYRYTPLLAWMLIPNCWGGQWSNFGKYIFMISDLITGIIILKLLSGISIAGKKLSTNKIIMLSSIWLLNPMVITISTRGSSESVLTVMIMLSLYYLINKKSIIASGFWLGLSIHFKIYPVIYLPSIMLYLSTSGTPFIDVPIVRWVNRTNIKFLITTLITIGAFNGIMYSIYGYEFLYNSYLYHLIRIDHRHNFSVYNVALYYKSALSEIAEASLGFFTGNMEKFVMLPQLSISALILPLLFARRDLISCIFIQTFAFVTFNKVITSQYFIWFLIFLPHYLAQSKLYSNKHMMKGIVALLLWIVSQGSWLYFAYQLEFLGISTFDNGLLFSSFFFYISNCWILSVFIDDLNNDL
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.  Required for cell wall integrity (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Glycosylphosphatidylinositol-anchor biosynthesis protein 14.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TIM44_MOUSE
Sequence: MAAAALRGGWCRCPRRCLGSGIQFLSSHNLPHGSSYQISRPGRELTLTKSYSSGSRKGFLSGLLDNIKQELAKNKEMKESIKKFRDEAKKLEESDALQEARRKYKSIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKSGEKLGKTAAFKAISQGVESVKKELDESVLGQTGPYRRPERLRKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDHFLHQCETDIIPNILEAMISGELDILKDWCYEATYSQLAHPIQQAKALGFQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQVVMVIKNSKGEVYDGDPDKVQRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (PubMed:31618756).  Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM44.
What is the protein family that this protein belongs to?
Belongs to the Tim44 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ABCG5_HUMAN
Sequence: MGDLSSLTPGGSMGLQVNRGSQSSLEGAPATAPEPHSLGILHASYSVSHRVRPWWDITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTSVDTQSKEREIETSKRVQMIESAYKKSAICHKTLKNIERMKHLKTLPMVPFKTKDSPGVFSKLGVLLRRVTRNLVRNKLAVITRLLQNLIMGLFLLFFVLRVRSNVLKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLRNIQEMPIPFKIISYFTFQKYCSEILVVNEFYGLNFTCGSSNVSVTTNPMCAFTQGIQFIEKTCPGATSRFTMNFLILYSFIPALVILGIVVFKIRDHLISR
What is the function of this protein?
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:27144356).  Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11138003, PubMed:27144356, PubMed:15054092).  Required for normal sterol homeostasis (PubMed:11099417, PubMed:11138003, PubMed:15054092).  The heterodimer with ABCG8 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
What are the official names of this protein?
ATP-binding cassette sub-family G member 5, Sterolin-1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: HUTU_VIBCH
Sequence: MTQSSAQGTRLDTQRTIRAPRGTQLRAKSWLTEAPLRMLMNNLDPDVAEHPHALVVYGGIGRAARNWECFDKIVEVLERLEDDQTLLVQSGKPVGVFPTHKNAPRVLIANSNLVPHWANWEHFNELDKQGLMMYGQMTAGSWIYIGSQGIVQGTYETFVAVAKKHFNGDAKGRWVLTGGLGGMGGAQPLAATMAGFSMIAVECDESRIDYRLRTGYVDKKANTLDEALAMIADTDRPISVGLLGNAADIFPELVKRNITPDVVTDQTSAHDPLNGYLPLGWSMEKAAQMRQQNEAEVVKAAKASMAIQVRAMLDLQTRGAATLDYGNNIRQMALEEGVANAFDFPGFVPAYIRPLFCEGIGPFRWAALSGDPEDIYKTDQKVKELIPDNPHLHNWLDMARERIHFQGLPARICWVGLKDRARLGLAFNEMVKNGELKAPIVIGRDHLDSGSVASPNRETEGMLDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGMVICCDGSDDAAERIARVLHNDPATGVMRHADAGYEIAKRCAQQQKLDLPMLNAELAKLK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_VIBVY
Sequence: MALTKADLAENLFEKLGFSKRDAKDTVEVFFEEIRKALENGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVENLK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NADC_METTH
Sequence: MMDIIREMIRADVGFEDITTEALIDRGTRVVADIVSREEGVVAGVEVAEMMAREFSISIIRWKDDGDPLSGGERVLTLEGDAMDILMVERTMLNLMMKMSGIATLTRSMLQRARAVNEGIRIAATRKTTPGLQWFEKQAVRIGGGDTHRFRLDDCAMIKDNHIAIVGNIEDAVRRVRDHVSFTKKVEVEVESPDDAVRAAEAGADIVLLDNMSPETIRNTLEELERRGLRDNVIVEASGGIKPDNIELYASTGVEVISMGFITASAHPVDLSLEIRGLK
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: MRGRD_HUMAN
Sequence: MNQTLNSSGTVESALNYSRGSTVHTAYLVLSSLAMFTCLCGMAGNSMVIWLLGFRMHRNPFCIYILNLAAADLLFLFSMASTLSLETQPLVNTTDKVHELMKRLMYFAYTVGLSLLTAISTQRCLSVLFPIWFKCHRPRHLSAWVCGLLWTLCLLMNGLTSSFCSKFLKFNEDRCFRVDMVQAALIMGVLTPVMTLSSLTLFVWVRRSSQQWRRQPTRLFVVVLASVLVFLICSLPLSIYWFVLYWLSLPPEMQVLCFSLSRLSSSVSSSANPVIYFLVGSRRSHRLPTRSLGTVLQQALREEPELEGGETPTVGTNEMGA
What is the function of this protein?
May regulate nociceptor function and/or development, including the sensation or modulation of pain.  Functions as a specific membrane receptor for beta-alanine.  Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor.  Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
What are the official names of this protein?
Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein: PNP_HAEIG
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKDVKEGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFFNEIQVVATVVSVNPQISPDLVAMIGASAALTLSGVPFNGPIGAVRVGFIDNQFVLNPTMAEQKQSRLDLVVAGTDKAVLMVESEADILTEEQMLAAVVFGHQQQQVVIEAIKEFAKEAGKPRWDWVAPQPNTDLINKVKAIAEARLGDAYRITEKQLRYEQIDAIKADVIAQITAEDEEINEGKIVDIFTALESQIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQDHFLFHYNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLAEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKSARMHILGVMEQAIPAPRADISDYAPRIYTMKIDPKKIKDVIGKGGATIRSLTEETGTSIDIDDDGTVKIAAVDSNAAKNVMGRIEEIVAEVEAGAIYKGKVTRLADFGAFVAIVGNKEGLVHISQIAEERVEKVSDYLQVGQEVNVKVVEIDRQGRIRLTMKDLAPKQETEINQEDSVEEQE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_AGRVS
Sequence: MNQNPIPNSFRSGPDEDGRFGIFGGRFVAETLMPLILDLQAEWENAKTDPSFKAELDHLNTHYTGRPSPLYFAERLTAELGGAKIYFKRDELNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYMGATDVERQAPNVFRMKLLGAEVRPVSSGHGTLKDAMNEALRDWVTNVDETYYMIGTAAGPHPYPEMVREFQSVIGKESREQMMAAEGRLPDMLVAAVGGGSNAIGLFHPFLDDESVRMIGVEAGGKGLDGNEHCASLTAGSPGVLHGNRTYLLQDSDGQIKDGHSISAGLDYPGIGPEHSWLKDIGRVEYVPIMDTEALEAFQLLTRTEGIIPALEPSHALAEVMKRAPKMGKDEIILMNLCGRGDKDIFTVGKILGMGL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: YCGM_ECOLI
Sequence: MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRVL
What are the official names of this protein?
Uncharacterized protein YcgM.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: RRP4_METKA
Sequence: MPEFELYVEDRQVVTPGELLARGQVIASEGTYTSGDEVYSKVTGLVDIDGRRIRVIPLAGPYRPSPGDFVVGIVEEVKFSSWLIDVRAPLPAILHVSNALEEEVDLIETDLSRYYRPGDVITAVVREVDPVQRVELSLLEDDAPTRLGRLQGGQVVEIDPVKVPRVIGRKGSMIKMLKRVLGCDIVVGANGRIYVRAREEPKKERELLAVRAIREIERRSHLRGLTDWLKANLKRLSRW
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_LEPIN
Sequence: MLSPKRVKFRKRQRGRLKGTDERGSSVSFGEFGLKAVTSGRLTARQIEAARITINRQVKRGGKLWIRIFPHTPITKKPAETRMGKGKGNPEFWIAEIRPGRILFEMSGIDEETAKKALSLASYKLPIHTEFVKRSAL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NUOH_NEIMF
Sequence: MIMQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGESEIVAGHHVEYSGFAFALFFLAEYIFMILIAALTSLMFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKVLIPIGFAYIVILGVWMISPLNLWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYI_SALCH
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPIELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVDQDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKDLVESVMQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGAYLPGTYPTLDGVNVFKANDIVIELLKEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQAWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSDQHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEEMVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLPGEREKYVFTGEWYDGLFGLEENEEFNDAFWDDVRYIKDQVNKELENQKANGIKSNLEAKVTLKYADDANGTIKKLKLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYTTDVGKVAEHADICGRCVSNIAGNGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.