PharMolix/UniProtQA huggingface dataset:
Protein: TGS1_YEAST
Sequence: MGRTFIHASKIKHAARKRKHHSNFRTLIKLLNNDAYKIESSKPLKNGKLFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDDRIWLKRGSWKKLVSKQKLSKIKYDCVFGSPPWGGPEYLRNDVYDLEQHLKPMGITKMLKSFLKLSPNVIMFLPRNSDLNQLSRATRKVLGPFAKCKVLYVKENGYMKGIFCMWGECFFNYEPASTENSRRESSEKEELSSENEELSKRKKHESTTTTKDNTVDIYDVNG
What is the function of this protein?
Catalyzes the two serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure.  The enzyme is specific for guanine, and N7 methylation must precede N2 methylation.  Hypermethylates the m3G cap on TLC1 telomerase which affects telomere silencing and telomere length regulation.  Required for pre-mRNA splicing, pre-rRNA processing and small ribosomal subunit synthesis.  Involved in nucleolar structural organization.
What are the official names of this protein?
Trimethylguanosine synthase, Cap-specific guanine-N2 methyltransferase, snRNA/snoRNA cap hypermethylase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.
Protein: SNAT2_ORYSJ
Sequence: MQMQAARPRVGVRPRGGIRPFPLPTLSFNNNSNRSACACACAVSVSDSELAARGFAVRRSSTGLDVGALNEVFARVGFPRRQEERLRRALEHSEVVWLEDSASSSAGRPVAFARAAGDGVFNAVVWDVVVEPSCQGLGLGRAVMERLVADLRGKGVSNIALYAEPRVVGFYRLLGFAMDPDAIRGMAFYRSRQQIQNTSS
What is the function of this protein?
Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin (PubMed:27121038).  Catalyzes in vitro the N-acetylation of tryptamine to produce N-acetyltryptamine, 5-methoxytryptamine to produce melatonin and tyramine to produce N-acetyltyramine (PubMed:27121038).
What are the official names of this protein?
Serotonin N-acetyltransferase 2, chloroplastic, OsSNAT2.
What are the subcellular locations of this protein?
Cytoplasm. Plastid, chloroplast.
Protein: CRL_ECOUT
Sequence: MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEPADDFRDEPVKLTA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVHD_TALVA
Sequence: MPPSLPCRCQEAPTPVFGYLYQIVELGVMRLFVEKRVFNEIPDEGILIADLATKTGIEFNLLERLVNFLISSRIFTSSSPGYVHHTPTSKYFTERRAQLWYPHIFDTFLTSAVKWPEYFDINGMQEPQCSSKSPFGFGSGYSDKSVYEIFDLMPKRSSDFNATMALSMGEMPILGMYDFSWIGEYGKRPEVKDRTLFVDVSGGKGQALQAILEAFPSIIPEQCVLEDQEKVIEEAKLATGPLETVKKVPIDLFGEQPVKGALVYYIRRVLNDWSDAEVVQILRSIRDACAPDSKVLISENLLPDEPPLKLAAIDVWMLNFGGKRRNKGNFGALARRAGFELSSIAEDDKTKSAVLELVVA
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of varicidin A, an antifungal natural product containing a cis-octahydrodecalin core (PubMed:30609896).  The PKS module of pvhA together with the enoylreductase pvhC catalyze the formation of the polyketide unit which is then conjugated to L-isoleucine by the condensation domain of the NRPS module (PubMed:30609896).  Activity of the Dieckmann cyclase domain (RED) of pvhA results in release of an acyclic tetramate (PubMed:30609896).  The cytochrome P450 monooxygenase pvhE then catalyzes the oxidation of the C21 methyl group to a to carboxylate group (PubMed:30609896).  The methyltransferase pvhD then further methylates the pvhE product (PubMed:30609896).  The Diels-Alderase pvhB is able to catalyzes Diels-Alder cycloaddition using both pvhE and pvhD products as substrates to form the decalin ring, yielding varicidin B and A, respectively (PubMed:30609896).
What are the official names of this protein?
Methyltransferase pvhD, Varicidin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: CLPS_BURP0
Sequence: MAIIPDKQDSSVLERKEQKLKPPSMYKVVLLNDDFTPMEFVVMVVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ADDA_STAEQ
Sequence: MIPTKPHDVIWTDAQWQSIYAKGQDILVAAAAGSGKTAVLVERIIQRILRDDVDVDRLLVVTFTNLSAREMKHRVDKRIQEASFKDPNNEHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLDIDPHFRTSSEAENILLLEQTIDDVLEQHYDKLDPHFIELTEQLSSDRNDDQFRSIIKQLYFFSIANPQPFEWLNQLAQPYKEENKQQQLMQLINDLAMIFMKAGYEELQKSYDLFSMMESVDKQLEVIETERMFITKAIEGKVLNTDVITQHEFMSRFPAINSKIKEANEGMEDALNEAKQHYDKYKSLVMKVKNDYFSRNAEDLQRDMQQLAPRVAYLAQIVQDVIQSFGVQKRSRNILDFSDYEHFALRILTNEDGSPSRIAETYREHFKEILVDEYQDTNRVQEKILSCIKTGEEHDGNLFMVGDVKQSIYKFRQADPSLFIEKYNRFSSSGNESGLRIDLSQNFRSRQEVLSTTNYLFKHMMDEQVGEISYDDAAQLYFGAPYDEVSHPVQLRALVEASSENSDLTGSEQEANYIVEQVKDIINHQNVYDMKTGQYRKATYKDIVILERSFGQARNLQQAFKNNDIPFHVNSKEGYFEQTEVRLVLSFLRTIDNPLQDIYLVGLMRSVIYQFTEEELAEIRVVSPHDDYFYQSIKNYMIDEKADSRLVDKLNRFIQDIQKYQNYSQSQPVYQLIDKFYNDHFVIQYFSGLIGGKGRRANLYGLFNKAVEFENSSFRGLFQFIRFIDELIDRKKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKKFNKGDLNAPVILNQQYGLGMDYFDVNKDMAFPSLASVAYRAINEKELISEEMRLIYVALTRAKEQLILVGRVKDEKSLIKYEQLAVSDTHIAVNERLTATNPFVLIYGVLAKHQSPSLPNDQRFERDIDQLNSEVKPRVSIVIDHYEDVSTEEVVNDNEIRTIEELKAINTGNEDVKIKIHQQLSYDYPFKVNTMKPSKQSVSELKRQLETEESNTNYDRVRQYRIGVASYERPKFLTQTKKRKANEIGTLMHTVMQHLPFREQRLTKDELFQYIDRLIDKQLIDEDAKEDIRIDEIMHFIDGPLYMEIAQADNVYTELPFVVNQIKVDGLTSEDEDVSIIQGMIDLIYESDGQFYFVDYKTDAFNRRKGMSDEEIGNQLKEKYQIQMTYYRNTLETILKRPVKGYLYFFKFGTLEIDD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: NLT43_HORVU
Sequence: MARAAATQLVLVAMVAAMLLVATDAAISCGQVSSALSPCISYARGNGAKPPVACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 4.3, LTP 4.3.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: CAP6_ARATH
Sequence: MATFNSFRKAVGAIKDSTTVSIAKVNSEFKDLDVAIVKATNHVESAPKERHIRRIFSATSVVQPRADVAYCIHALAKRLSKTRNWVVAIKVLIVIHRTLREGDPTFREELLNYSHRGHILRISNFKDDTSPLAWDCSAWIRTYALFLEERLECYRVLKYDIEAERLPKGSGASSKNVDFNASQTYRTRMLSDEELLEQLPALQQLLYRLIGCQPEGSAYSNYLIQYALALVLKESFKIYCAINDGIINLVDMFFEMSRHDAVKALNIYKRAGQQAENLADFYEYCKGLELARNFQFPTLRQPPPSFLATMEDYIKEAPQSGSVQKKLEYQEKEEEEQEEEEAEHSVQPEEPAEADNQKENSEGDQPLIEEEEEDQEKIEEEDAKPSFLIDTDDLLGLNEINPKAAEIEDRNALALAIYPPGHEAPGPSNILSLIETGGSGWELALVTPQNNNNNNNPRPAPNTKLAGGFDNLLLDSLYEDDSARRQIQLTNAGYGHGGIDTTAAPPNPFQMQQDPFAMSNNIAPPTNVQMAMQQQQQQQMTMMHQSPYNYTHPHDYHQNHHHHQFSAGPSPSNPFGDAFLALPPPPGSAGPQQNNHHHMLL
What are the official names of this protein?
Putative clathrin assembly protein At4g25940.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: Y034_NPVOP
Sequence: MAALVKPMLPLATFGGQQNGCLQHQLAKLVQARARRGYEHDIGQLAEKLKKRQVARGHLGDVLEQMGRQSELLPELVKNDEEFRIVQQRDLGHNTIEYLNLLQHDKLFSCRLCYTHAHWLWCEFHKTHAYRGPRDISVDAYVDHLNSDMGVVALVEEYYHWLSSCNDKAEAKRALKTLANVESLGDLLDSYNYSSVDADTSSYELMDFE
What are the official names of this protein?
Uncharacterized 24.0 kDa protein, ORF26.
Protein: RLMN_STRT1
Sequence: MSEVTTQSKPERRKRQKLEDMEGYKPSIYGLTRDELIDWAVEHGEKKFRATQIWDWLYKKRVQSFEEMTNISKDFIAKLNDNFCVNPLKQRIVQESKDGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLTAGEIVAQIMLVQKYFDDRGDGERVSHVVVMGIGEPFDNYDNVLRFLRTINNDNGLAIGARHITVSTSGLAPKIKEFANEGVQVNLAVSLHAPNNDLRSSIMRINRSFPLEKLFEAIEYYIQTTNRRVTFEYIMLNEVNDHPENAQELADLTKKIRKLSYINLIPYNPVSEHDHYSRSTKERVAAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAVAEASGKSEGK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_NITWN
Sequence: MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRCGAIAARAPVMDAVRAFASDGGLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEGEGRVLYRYCSASGEVGDTHNINGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_FRACC
Sequence: MLRSVVLAGGGTAGHVEPALAVADALRATDSRVRLTLLGTATGLEARLVPARGHELATVPKVPMPRRPTPAVFKLPARFLDAICQAGETLDLVRADVVVGFGGYVSAPAYLAARRRGIPIVVHEANPLPGLANRLGARLTPFVATSYPSTPLRGATLTGIPLRGEILTLDRSPAAMRAARARYGLDPHRPTLLVFGGSQGARSLNQVMTAAAHPLAAAGIQVLHATGPKNFDEVAAALPLDLPTPYELRPYLDHIPSAYAAADMTLCRSGAMTCAELAAAGLPAVYVPLPHGNGEQRRNALPTVEAGGGLLVDDAELSASWLLENALPVLISAERLAKMSAACAGSGHPQAAAAIVAMIRDAAATRRRSRPRHAAP
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ADRX_ENCCU
Sequence: MDMFSAPDRIPEQIRIFFKTMKQVVPAKAVCGSTVLDVAHKNGVDLEGACEGNLACSTCHVILEEPLYRKLGEPSDKEYDLIDQAFGATGTSRLGCQLRVDKSFENAVFTVPRATKNMAVDGFKPKPH
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Adrenodoxin homolog, Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
What are the subcellular locations of this protein?
Mitosome.
Protein: LGT_BUCBP
Sequence: MYIHFPQFSPIIFSIFSIPIRWYGLMYFLAFIFALWRGKTRAEYYNLTQIEVENLLYSCFIGLFIGGRIGYIIFYNPVFFFENMSHILKIWEGGMSFHGGLLGVIIVLLFFSKKLNKHILEISDFIVPLVPFGLGAGRLGNFINGELWGRIAPDFKFSVLFPNSREIDLNVAANNLELKSLIEKFGVLPRHPSQIYEFVLEGLVLFFVLNYFSKKSMPFGFVSSIFLILYGCFRIFLEIFRQPDRQIGLFLNTFSMGQLLSMPMIVLGILIAINIYVKVL
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VSPKA_GLOHA
Sequence: VIGGDECNINEHRFL
What is the function of this protein?
Snake venom serine protease that hydrolyzes specific chromogenic substrate S-2302 suggesting that AHP-Ka is a plasma kallikrein.  Has esterase activity on alpha-N-benzoyl-L-arginine ethyl ester hydrochloride (BAEE) and amidolytic activity.
What are the official names of this protein?
Snake venom serine protease AHP-Ka, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ESIP1_HUMAN
Sequence: MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWGI
What is the function of this protein?
Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity).  Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity).
What are the official names of this protein?
Epithelial-stromal interaction protein 1.
Protein: FAKD5_PONAB
Sequence: MAATLKSLKLLRYQAFCSPSAFGAVRSVSYWNASSTQHGGQDPPGHISLCHSAKKVKNICSTFSSRRIPTTSSARPGLEFSKTSSSKASTLQLGSPRATGIDEENVEVFDSFENLRVFLQLRPEYRVHSYSASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVRKIKLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMSVDQLLLVADLWRYIGRKVPRFLNICCSYLNLRWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSKTNLSEFVMRKIGDLACADMQHLSSHSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLDEGVMNAVAASLPPRVAQCRSKDVAKILWSFGTLNYKPPNAEEFYSSLINEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLIKELYTLDGTVVIECPDYRGNRLSTHLQREGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLKCEHVGVSLTDDLMNQLLKGKARGHFQGKTESEPGQQHMELENKAAVPLGGSLRNVADKSGAMEMAGLCPPACMQTPRMKLAIQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
What is the function of this protein?
Plays an important role in the processing of non-canonical mitochondrial mRNA precursors.
What are the official names of this protein?
FAST kinase domain-containing protein 5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FAST kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.
Protein: ATG3_CANAL
Sequence: MSLRSKLSSLREYLTPINHNSNFVTTGEISPEEFVKAGDYLVYKFPTWQWGNDCPKNLQKSFLPPDKQYLVTRHVPSYQRASNYLTGEDKKGANPEEDDEEEEEEDEEGWVKSKKIHKVIDDTHDSQINKGEEINDIDDFIDENAEEQEHDQIGDHELDDDEFDDLDIINDSKNNKLRRFDLYITYSTSYRVPKLYLVGFDSNGIPLLPQQMFEDINSDYKDKTATIENLPVAHNTTSVSIHPCKHSSVMKVLMKHSKLNKKNLQQKDESLSDDLSKLSVNEKKTQDEHSQINNDDKEEEEEGIRVDHYLIIFLKFIASVTPGIEYDYTMDAL
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DVL3_XENLA
Sequence: MGETKVIYHLDEQETPYLVKLPVPAEKVTLGDFKNILNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVCWLVSADGSQSDAGSVCADIQSDLPPPIERTGGIGDSRPPSFHPNTRGSQENLDNETETDSVVSARRERPGRKETSEHATRINGTSKMERRRDTGGYESSSTLMSSELDSTSFFDSDEDDSTSRFSNSTEQSSASRLMRRHKRRRRKPKAPQIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLRDIVHKPGPITLTVAKCWDPSPRNCFTLPRSEPIRPIDPAAWVSHTAAMTGTYPAYGMSPSMSTITSTSSSITSSIPETERFDDFQLSIHSDMVTIVKAMSSSESGLEVRDRMWLKITIPNAFIGSDVVDWLYHHVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGDLCGNMANLSLNDHDGSSGTSDQDTLAPLPHPGAAPWPIAFQYQYPLPHPYSPHPGFPDPAYIYGGGSAGSQHSEGSRSSGSNRSSTEKRKDRETKGGDSKSGGSGSESDHTTRSSLRRDRAASERSVPASEHSHRSHHSIAHSIRSHHTHQSFGPPGIPPLYGAPMMMMPAPVSVMGPPGAPPSRDLASVPPELTASRQSFRMAMGNPSEFFVDVIKEFWGV
What is the function of this protein?
Involved in the signal transduction pathway mediated by multiple Wnt genes (By similarity).  Required during ciliogenesis for the docking of basal bodies to the apical plasma membrane.
What are the official names of this protein?
Segment polarity protein dishevelled homolog DVL-3, Dishevelled-3, DSH homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DSH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_SYNPW
Sequence: MAAVSLSVSTVKPLGDRVFVKVSESEEKTAGGILLPDTAKEKPQVGEVVQVGPGKANEDGSRQAPEVGVGDKVLYSKYAGTDIKLGSDEYVLLSEKDILAVVN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF1_DEBHA
Sequence: MMIKEEAEGILKQRNSKLEELLHLAADPLLTDISSHKSRVSEFLNDNDITKEKTFVVSSLPGVSGSGSFAEAMSQSVSKSIYKVEEAKERTENAAIEQGLKRRTESISDDRKLKISRKSSSQLSDSRSGSISKSTSEITKPVAPPVKSQKENIHLETKDFLNRDIGELEILSVPEHYPTKPPNVSSLAELYYLTQTLPLIKLLPGSHKTLITENYELALLEGKIAVLYSRIEELKRQGKWSLRQPKRYYDPYIYTKSNNGKKTFHGDSLLEEGKWMAADFKEGSKYKKACCVTMAQAVNDYWTYGKVMCIRRKRIWHIGERREEEEIHGDLETDLVDGADSMAIDDINVDNDCAPLEITGNELQNIVVSDDKVSTEPISNDEPQRKEEDDIDSAEVADQEVSEDPSQDKPVDELIPEEEVELSSIDVKLLLSRPKPEDEIVPTNLPTFSEDDLKEMGRDSKDSAPFKLHANLNDLKKIDQSIIKNLPKFTAFDNEDSNMPAPALKPVDSPMIAVSRLLHPFEEDDEWYKIVLKEGDSHKSKSNVSSGPPEYQKGLFGFQSHRRFNYLKPPKPPLIKNIEFRSPTIWLPQDDKHLIHYVAEFCFNWDLISEHLSPSAATLRKYESNIERRTPWQCFERYIQLNEKFQFSDMKGIYSYQAQSWLEHAHRAQSTTKRRISPLGVGNESIQRGHRRLRWASLFDAMRKSMKKREDAIAKLNHRRTPVDYSANNTNVNSPEASNNGTPGPNNGKRPMDRVPTPAELSKLKFERDKSIQEAYLNQQATRSRMIAAVAQQQKQQQNNQGNIPRPPSQGPGPNVGVPPPQRGQIGVQGGPTNTPTGSLGNQVPPSQQPSQAAQGGMTKRPTTPNGTAYTAEQIQQLLQIQKQRRLMQQQNQPGKTGISPSQPNTPALMQNMPLSSNKTTVGGSNMPLSGMPNSTQQVSLSQQGQKQQLGPSQRQQVPVSQPSQGQGSSTGVPANKSRIHFAPAQVSAIINSIQTKNPNLTKEQVTKLAATYLANIQQQQQNRANQQQQQPPSQHSGAIGQGPAAHRPGQSQSPSNQKKPQVATLTPQERNQLQMLKAAKTAQQQQLQHQQQQQQQQQQQQQQQQQRRPGSPMVPNAPLDPNNMAKLEYEQRKNLLIQKHQQQQRLGNNSNIPGQSTPNLASMPPSSSSSPSSSVSGPASNLPNSNKNVPKK
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI2_CUPPJ
Sequence: MSTSLSAWQSLREHAAKIRHTHMRDWFTGPQGQARSVRLTVEACGLTLDYAKNRVTEDTLSLLFALARQARVCERRDAMFAGEPVNTTERRAALHMALRAHPGDGYRALGVPVEADVSAVLAQMERFARDVRSGSWTGFDGRAITDVVNIGIGGSDLGPRMVCRALEQDTEPGPRLHFVANVDGYDLARTLARLDAATTLVIVCSKTFTTLETMANARTARDWFLRHGVTHSDLARHFVAVSTNRDAVAAFGIDPVNMFPFWDWVGGRFSLWSAVGLSIAVAIGFDRFRQLLDGARAMDRHFAGAPPEQNLPMILGLLDVWYRSFLGTASRCVAPYCEPLDLLPAFLQQLEMESNGKSVQHDGAALEAGSAAVVWGTTGTNGQHAYFQMVHQGSQLVPVDFIACLQPHSDLPGHHTKLLANCFAQGEALLRGRTADEVRAEGKADEALVPHLVFEGNRPSNTLLLQRLDAFHLGALLAMSEHRTFVQGALWNINPFDQWGVELGKMLARPIERELEGAPPQPHDASTAALIRRAAQFCASTD
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 2, GPI 2, Phosphoglucose isomerase 2, PGI 2, Phosphohexose isomerase 2, PHI 2.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA054_BOVIN
Sequence: MDVLFVAILAVPLILGQEYEDGEELEEDEYYQVIYYYTITPSYDEFGVNFTVDYSMFESENTVNRLDEKVEASETTISYETDRADHQKPVIEKPVTMEPQSPDLNDAVSGLQSPGPLLLSWALIQGVMYFL
What are the official names of this protein?
Uncharacterized protein C1orf54 homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: Y181_MYCGE
Sequence: MDNFINGYIPRNSFVHKLHPTTKLVIFLLLVILVFVPIGFVFQSVIFLFVTFVFFIAKLPGRFYSSAIKSITLLFLLLLFVNWFTFRDPGFYLTSDQLNSLPAIDNSKFSFWNISLFNYQDNVFSQVFAFNRGNLTNLNQLDFFYKANNADSYTKVKGIDSLASMLANNGNGLSKDKILSAFLDHNLNLYLARSWGANFAGFVVDFNPTTQLFKLTPFLANASYVLTLRAVILAFYVTQKILIMILFATVLTSTSSSVELAYGIERLLWPLKLIKIPVNVFAMTIAIAIRFVPSLLLESQRILNAQASRGLDFRNGGFLVKMRSLSSLVVPMVSIAFRNASELASAMEARGYHPAKKRSSYRQYKITWIDILALFLVFAWFVVIIFLTIRGAVFLDLGTPEWLLTGKINEQVIRDLKVSG
What are the official names of this protein?
Uncharacterized protein MG181.
What is the protein family that this protein belongs to?
Belongs to the CbiQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_STRPJ
Sequence: MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKARHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEELIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.