PharMolix/UniProtQA huggingface dataset:
Protein: PESC_ASPFU
Sequence: MGKIKKKGTSGQAKNYITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKASKTSTPNTTFYYTKDIQYLLHEPLLRKFREQKAVAKKIARSLGRGEVGDAARLEKNHAPKLTLDHVIKERYPTFIDALRDLDDALSLLFLFANLPSTAHVPPKTIALCQRLCHEFQHYLITTNSLRKSFLSIKGIYYQATIQGQDILWLVPYRFVQRVNGDVDYRIMATFVDFYTTLLGFVNFRLYSSIGLRYPPKFDTRSDENGAELAAFTLEGRGVGDAPKAIEAGNTQATTSTNNKEVSKEIQAKVDNVIKSAGLDEAKEEPAAETTEESSETIDKFEPAAPEADTLPQPDLSGNEAGSLFAPFTFYISREAPRAPLEFILRAFGCKRIGWDAVLGDGAFTHDETDTRITHQIVDRPQLPESSLPAIPAASKDGSDAVQKVKPGTRIPGRTYVQPQWVWDCINEGRLVRPDLYAPGATLPPHLSPWVKPSRGGYDPKASLAEQEEEGEAELDEDSDEEMEEATSDKKAEAKADVGSESEDEDESVDGGMDVAGTDDDESESEDEEEDFDGFEEEAASESEDEEEAARTQHQKELEAEAAGLPFSSNGATSDGSKKKASQAKKIAAKKRKEEEELERQKMMMSRKKRKLLEKMIYSNKKQSEEAAKLRSKRRKLEKGAAK
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: Y370_KLEP7
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRGVEATFELNDANKTIKVLSESDFQVNQLLDILRAKLLKRGIEGTSLDVPEDIVHSGKTWFVEAKLKQGIESAVQKKIVKMIKDSKLKVQAQIQGEEIRVTGKSRDDLQSVMALVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein KPN78578_03700.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: YQAI_BACSU
Sequence: MVENPMVINNWHDKLTETDVQIDFYGDEVTPVDDYVIDGGEIILRENLERYLREQLGFEFKNAQ
What are the official names of this protein?
Uncharacterized protein YqaI.
Protein: RNH_SYNC1
Sequence: MSESRSMVEIFSDGACSGNPGPGGFGTLLRCGERVRELSGFDPETTNNRMELLGAIAGLEALTRPCRVRLTTDSQYVCKGMTEWIHGWQKKGWKNSKKEDVANRDLWERLLVLVSKHEVSWHWVRGHAGHAENERCDELARQAIADGCSSVV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSME_RICCN
Sequence: MKYNRIYINSRLAENSKIELASDHHVHYVKTVLRLKVNDGLRLFNGTDGEFLAQINDIGKNNLSVRLKEQLKKPYTKSTLTLAVAIIKQDKLMLAINMATQLGITKIIPLITRWCQFRSVNIERLTKCVIEATEQSERLTPPIIEKAITIQDYLKKNNNLMLYANEHEKEENSILRISSSLSNSDITIIVGPEGGFTNDELELLASYKNTKSISLGSNILRAETAAITAIAQVRLLGSHCEEIA
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_PORPU
Sequence: MNSIVNITPIIIILSEHSSEHTFGFNSDIFEANVINILLLLFGLIYVLKQSLGSTLNERQLKVLAAIQESEERLEQASSRLSESEKQLAQTQIIINQIKKEAQLTAEKVRSSILAQGQIDIERLAITGKSNIETAEKQIRRQIQQQIAFLALKKVTLQLENQMSSDIQLRIIDNNIAKLGDQL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GAL1_ALIF1
Sequence: MTNLIKNVKDAFNSVLSYAPTHIVQAPGRVNLIGEHTDYNDGFVLPCAINYQTVVAAAKRDDNIVRVVSVDYGNETDEFDITQEITFQENKMWSNYIRGVVKCLIDRGYEFKGADISVSGNVPQGAGLSSSAALEVVIGQTFKELYNLNISQAEIALNGQQAENEFVGCNCGIMDQMISAEGNENHAMLLDCRSLETTAVSMPEDMSVVIINSNKKRGLVDSEYNTRREQCEEAARIFGVKALRDVTIEEFNAKAHELDEMVAKRARHVITENDRTEEAAKVLASGDMKRMAVLMAESHASMRDDFEITVSEVDTLVDIVKNVIGAEGGVRMTGGGFGGCIVALVPPMLVDEVKAAVEELYEAKTGLKESIYVCQATNGAGLVL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_CANAX
Sequence: MGLLSIGTPLSWDESKKYNNHVRTNGITQLINIFKQHGYRENDVFLWGDEVEYMLVDFDETKKTARLSIDKDYIINDLNDPDKLLPIAEKQDVSYHPEYGRFMVEATPAKPYNGNLLSDYLYIEKNMIIRRQLCEDNLPSHIKLLTLTTFPRMGCNIFTSPPSKPDGIASQSLFLPDEIINRHARFPTLTANIRKRKGHKVAINLPIYPDKSTKLLDDTIPQNRELFDSDKEPWIGASKPGFIYMDSMGFGMGSSCLQITMQTKNISQARYLYDSLAPIAPIMLSLSAAAPIFKGFLVDQDVRWNVVSGAVDDRTFIEKGQEPYSGYHLFGGLDIDAQDKLRINNHQINQQGDLLDLYTKDGKPIQRVPQSRYDSIDNYLNDNYYDTKYFQDEYNDLNAPINEQVYQRLIDEGKLDKYMANHFAHLFIRDPLVIFSERINQDNNLENDHFENIQSTNWQTLRFKPPALYTKDTDLTTKPGWRVEFRPMEIQLTDFENAAYSSFITLLSKAILKFQPNFYIPLSKVEINMKLAHKVDSTLKDKFWFRSFELWNIDPQEFDDYGFEWFDQFINGNQQQNGHVNNNNNNDKKTKNDPIIVNGSTTTTNGTNSGSGITETNGTMLPKGCEGKTVEEINDVDDNGIDQRYTICQLINGSGEFPGFIKLVIKLIATDLVPQALNNSTISKEQLIEN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 3 family.
Protein: SEY1_NEUCR
Sequence: MNGHFAAVDNGNGSSPDSNAHSFEHGIQVINEDKQYNTNLNEYLNETHVAEAGFNYHLISVFGSQSTGKSTLLNHLFGTQFSVMSERERRQTTKGIWMSKNKNEGKMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNMQLFLKDKQNQTRSLLFFVIRDHIGVTPLANLRNTLIQDLTHIWSSISKPAGLENSKIEDYFDFAFAALPHKILQPDKFISEVQNLGSRFIAGHRNKDSDATDDQELTGGVFLPEYHRRIPADGLSIYAEGIWDQIVSNKDLDLPTQQELLAQFRCDEIAREVQIAFDAAIAPLEEQQAESTRAGKPAVLPNLGQIGAEAREKCVKNFETQASRYHKGVYTTKRAELEDKIDNRLKALYQAHLTAAHKAGVTAFSEAVANAVKAGQKAGGAYEFAEIVEKQKTKTLEIFKKEAQSLAIPGVAWSNFKPQYLIFEKELDEVSARLRKEEMRRLAIRVERWVKSRLGDAIGLEFNKLGSGRGGSGAPESGEKPATEKDIWDRVWKAFISIVGEAESRFTDRAKSFEASDDEVQVGLWRLRRKSWVALREKIEEEVMESNILMKLRENFEDKFRYDEDGVPRIWRPSDDIEGIYTRARESTLGLVPLLSRFRLTSTSAPPDLIEFVGPQPHGVEPGDEEDLTPIGGVDEDEGKSLEEETTILSEPKKQDLVVRFKKMADGVYVEAKRSAIGGITQVPLYFYAVLLVLGWNEFVMVLRNPILFLLLLLISGGTYVAYSLNLLGPMMQMANAASTQGMEIGKAKLRDFLENHEGARGALGMPPKNAQRVESGISMDTLDSNGKRKETGLGAEDDI
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein sey1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: IL12A_MARMO
Sequence: MCPSARSLLLLASLVLLEHLGSARNLPRSTPVPAVSQECHNLSQTLLSTVDSALQNAIEILEYYPCSAEEVNHEDITKNRTNTVKACLPQELAQNENCLASRETSFIIKRSSLTSGRTSWNTTLCFSSIYEDLKMYQLELKAISEKLLMDPKGQIYEDKALLAAVDYLMQAVNVNNETVPQTPSPEAPSSNLYRTKTKLCILLHALRIRAVTINRVMSYLNSS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_CLODI
Sequence: MNIKPFGDRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7955_DICDI
Sequence: MSTMYAREYAGNPIKPDVNIFQNKSFKQGEKPKKLDEDYFLYSLKSLFKDNLNEYPGKQLDRPNKLDITAADDRELNFLEEKKWDEKELLKEQRAETFKNFTFPPHMSIQEKCVDQLQQDYDDFHMLCLRDMFRDKECDLEGFSRTPAQDKDELKEMNLTHESLLKEKSKLPLKKQQQNKSSNKINGKLNKKKISPNQKRTIIRQTKTTTTRIFKKPISSMEPITKTEITSKTITRPVTEIPSNDPKSKPKLSTQTSYSVDLSHLNNNSWVWDNGETRKL
What are the official names of this protein?
Putative uncharacterized protein DDB_G0288489.
Protein: XYN5L_ARATH
Sequence: MNSIKNGFFLCMIFLLWCHVDSGVSIDPFSHSHSLNTECVMKPPRSSETKGLLQFSRSLEDDSDEEWKIDGNGFIREMAQRIQLHQGNIYSFSAWVKLREGNDKKVGVVFRTENGRLVHGGEVRANQECWTLLKGGIVPDFSGPVDIFFESENRGAKISAHNVLLKQFSKEEWKLKQDQLIEKIRKSKVRFEVTYENKTAVKGVVISLKQTKSSFLLGCGMNFRILQSQGYRKWFASRFKITSFTNEMKWYATEKARGQENYTVADSMLKFAEDNGILVRGHTVLWDNPKMQPSWVKNIKDPNDVMNVTLNRINSVMKRYKGKLTGWDVVNENLHWDYFEKMLGANASTSFYNLAFKIDPDVRLFVNEYNTIENTKEFTATPIKVKKMMEEILAYPGNKNMKGAIGAQGHFGPTQPNLAYIRSALDTLGSLGLPIWLTEVDMPKCPNQAQYVEDILREAYSHPAVKGIIIFGGPEVSGFDKLTLADKDFNNTQTGDVIDKLLKEWQQKSSEIQTNFTADSDNEEEEVSLLHGHYNVNVSHPWIANLSTSFSLEVTKEMDQDQVIRVVISA
What is the function of this protein?
Binds to and hydrolyzes insoluble and soluble xylan substrates.
What are the official names of this protein?
Endo-1,4-beta-xylanase 5-like, AtXyn5-like, Xylan endohydrolase 5-like, Xylanase 5-like.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: CLS2_STAAC
Sequence: MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase 2, CL synthase 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCPA_TRITO
Sequence: MRSVLSLALLAANVVTAAVVSPFDYSGYKVIRVPTQKDNVKEVQRIITDLNLDTWKYPKSEGQNADIVVPPSQITSFMERISGMSMEMMHEDLGMSISNETSFEAYSAGYAPDINWFKSYHSYQDHISYLQDLQGLFRTRSEYVDAGKSHEGRTIPALHIWGSGGKNSKPAIIFHGTIHAREWITTMVTEYLAWSLLSQYNKNADITSIVDNFDIWVFPIVNPDGFAFTQTSNRLWRKNRQPNPNARCPGRDLNRNYPYQWVGPGSSSNPCSDTYRGAQPGDGTEIKVHIANMKRIASYHGIAMFVDWHSYGQLFMSPYGYSCTARPPTDARHQELSRIFAQALRAVHGTPYRTGPICNTIYQVNGDSVDYALEVLKVKLSLTAELRDTGARGFVLPADQIVPSGEETLAGTVAMLKAVIRG
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Metallocarboxypeptidase A, MCPA, Carboxypeptidase M14A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPOE2_HUMAN
Sequence: MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSNMIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFGTPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDAIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQVFHVNAFGFPPTEPSSTTRAYYGNINFFGGPSNTSVKTSAKLKQLEEENKDAMFVFLSDVWLDQVEVLEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICEYPDIHQSSRFVFVPGPEDPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLVNKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVIADKYDPFTTTNTECLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGF
What is the function of this protein?
Accessory component of the DNA polymerase epsilon complex (PubMed:10801849).  Participates in DNA repair and in chromosomal DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase epsilon subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_BURO1
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMSNSLIEHEVIKTTLPKAKELRKVVEPLITLGKKPSLANRRLAFNRLRDRDSVAKLFDVLGPRFANRPGGYLRVLKFGFRVGDNAPMALVELLDRPEVDETENVQEAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SSRP_VIBC1
Sequence: MVKKKSKQKAGSNTIALNKKARHEYFIDDEIEAGMELQGWEVKALRQGKANIAESYVFMRDGEAFVSGMTITPLNQASTHVVANPTRVRKLLMSRRELDNLLGRINREGMTLAALSLYWSRSWVKIKIGVAKGKKLHDKRTDLKEKDWAREKARVMKSSLR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RUXF_HUMAN
Sequence: MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077).  As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319).
What are the official names of this protein?
Small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes.
Protein: GMHA_BURP1
Sequence: MENRELTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCEL_VACCW
Sequence: MDANVVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGVKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNETVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSNGLYCYFTHLGYIIRYPVKRIIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAINDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFVEYKKFSNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDIFNEDKLSDVGHQYANNDKFRLNPEVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFNIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRIVVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTRNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR
What is the function of this protein?
Catalytic subunit of the mRNA capping enzyme which catalyzes three enzymatic reactions: the 5' triphosphate end of the pre-mRNA is hydrolyzed to a diphosphate by RNA 5' triphosphatase; the diphosphate RNA end is capped with GMP by RNA guanylyltransferase and the GpppN cap is methylated by RNA (guanine-N7) methyltransferase.  Heterodimeric mRNA capping enzyme catalyzes the linkage of a N7-methyl-guanosine moiety to the first transcribed nucleotide (cap 0 structure), whereas the methyltransferase OPG102 is responsible for a second methylation at the 2'-O position of the ribose (cap 1 structure).  Also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I/OPG123 and the RAP94/OPG109 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94/OPG109, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA.
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme D1 subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: MIAB_YERPN
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLASTHGYQLTTIPEEADLLLLNTCSIREKAQEKVFSLLGQWKLLKEKNPQLIIGVGGCVASQEGEQLRQRAPCVDVIFGPQTLHRLPEMINHVQGTNSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAYRGATYDGDICSFAELLRLVAAIDGIDRVRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQSGSDRILTMMKRAHTALEYKAIIRKLRQARPDIQISSDFIVGFPGETQQDFEQTMKLVADIHFDTSYSFIYSPRPGTPAADLPNNVSEEEKKQRLHILQQRISQQAMEISRKMVGTVQRVLVEGTSRKNVMELAGRTENNRVVNFEGSPDMIGKFVDVEIVNVYASSLRGILLRTEDQMDLRTHESPQSVIARTRKENEIGVGIYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGAT2_RAT
Sequence: MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLNRSKVEKHLQVISVLQWVLSFLVLGVACSVILMYTFCTDCWLIAALYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIVIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVPKLEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEVLEVN
What is the function of this protein?
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Required for synthesis and storage of intracellular triglycerides (By similarity).  Probably plays a central role in cytosolic lipid accumulation.  In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity).  Functions also as an acyl-CoA retinol acyltransferase (ARAT) (By similarity).  Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Cytoplasm, perinuclear region.
Protein: PSAJ_PROM5
Sequence: MFKIFNTKFMRSAPIVAAIWISLTAGIIIEFNRFFPDLLFHPMS
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.