PharMolix/UniProtQA huggingface dataset:
Protein: TTL12_MOUSE
Sequence: MEIQSGPQPGSPGRAERLNARLLDEFVSLHGPTLRASGVPERLWGRLLHKLEHEVFDAGEMFGIMQVEEVEEAEDEAAREAQRKQPNPGGELCYKVIVTSESGVRADDPNSIFLIDHAWTCRVEHARKQLQQVPGLLHRMANLMGIEFHGEVPSPEVVALVLEEMWKFNQTYQLAHGTAEEKVPVWYIMDEFGSRIQHSDMPSFATAPFFYMPQQVAYTLLWPLRDLDTGEEVTRDFAYGEADPLIRKCMLLPWAPADMLDLSFSTPEPPAKYYQAILEENKEKLPLAISPVARPQGHVFRVHCDVQQVLGHLTHPRFTFTDSEADADIFFHFSHFKDYMKLSQESPQVLLNQFPCENLLTVKDCLASIARRAGGPEGPPWLPRTFNLRTELPQFVSYFQHRERRGEDNHWICKPWNLARSLDTHVTNNLHSIIRHRESTPKVVSKYIESPVLFLREDVGNVKFDIRYIVLLRSVRPLRLFAYDVFWLRFSNRPFALDDLDDYEKHFTVMNYDPDVVLKQVHYNEFIPQFEKQYPEFPWSDVQAEIFKAFTELFQVACAKPPPMGLCDYPSSRAMYAIDLMLNWDNHPDGKRVMQPQILEVNFNPDCERACRYHPSFFNDVFSTLFLDETDNCHVTRII
What is the function of this protein?
Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues.  Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3).  Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability.  During RNA virus-mediated infection, acts as a negative regulator of the RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
What are the official names of this protein?
Tubulin--tyrosine ligase-like protein 12, Inactive tubulin--tyrosine ligase-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Predominantly localizes in the cytoplasm.
Protein: HTPX_ACIBS
Sequence: MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQAMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXH_PSEPG
Sequence: MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSSRYKLARKLRSESRTQTRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLMU_CUPNH
Sequence: MNIVILAAGMGKRMYSDLPKVLHPVAGRPMLAHVLDTARALSPSRLVVVVGHGAARVREAVAADDVAFAEQPQQLGTGHAVMQALPLLDDSQPTLVLYGDVPLTSAATLQALVAEAGTQRLGVLTVEMPDPTGYGRIVRDAAGSIVRIVEQKDASEAEKAIREINTGIIVCPTGHLRKWLSTLRNDNAQGEYYLTDTVERAVADGVETVSAQPAAIWETLGVNSKLQLAEVERIHQGNQARRLLEAGVTLLDPARIDVRGELSCGRDVTIDVGCVFEGRVHLEDGVRIGAHCVIRNSTVGAGAQVHPFCHIDEARVGPAGRIGPYARLRPGTELGEDVHIGNFVEVKNAQVAAHSKANHLAYVGDATVGSRVNIGAGTITCNYDGVNKHRTVIEDDVFIGSDTQLVAPVTVRRGATLGAGTTLTKEAPADKLTLSRAKQLTIDAWQRPVKQPKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_BACTN
Sequence: MNFKKGEVLFFNKPLGWTSFKVVGHVRYHICRRIGVKKLKVGHAGTLDPLATGVMILCTGKATKRIEEFQYHTKEYVATLRLGATTPSYDLEHEIDATYPTGHITRELVEETLTHFLGAIEQVPPAFSACMVDGKRAYELARKGEEVELKAKQLVIDEIELLECRLDDPEPTIRIRVVCSKGTYIRALARDIGEALQSGAHLTELIRTRVGDVRLEDCLDPEHFKEWIDRQEIENDEDNN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: THIE_PASMU
Sequence: MKPVHAFMRLYFIAGTQDCLHLDGDPAQNLLNILQQALQSGITCYQFREKGKKALQDPDKIKALAIQCRDLCRQYQVPFVVNDDVQLAIDIGADGIHVGQTDMAVADVAALCHSHCFIGTSVNTLEQGIAAQANPLIDYFGTGPIFPTQSKEDPKPVVGVDFVSTIRAHGIDKPIVAIGGVTTQTAEELRRRGANGVAVISAITQSADIAKTVKELLGNAQ
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: DNAK_AERHH
Sequence: MGKIIGIDLGTTNSCVAILDGDHARVIENAEGDRTTPSIIAYADDGEILVGQPAKRQAITNPKNTLFAIKRLIGRRFEDDEVQRDLEIMPYAIAKADNGDAWVEVKGKKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAAFAYGVNKVKGERKVAVYDLGGGTFDISIIEIDEVEGETTFEVLATNGNTHLGGEDFDNRVINYLVEEFKREQGIDLRKDQLALQRLKDAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDMVKDSLEPVRVALKDSGLAVGEIDDVILVGGQTRMPMVQKAVADFFGKEPRKDVNPDEAVAMGAAIQGAVLSGDKTDVLLLDVTPLSLGIETMGSVMTALIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLEGIRPAPRGLPQIEVTFDIDANGILHVSAKDKETNKEQKITIQASSGLSDDEIERMVREAEANAAEDKKFEELVQTRNQADGLVHSVRKQITEAGEALPADDKTKIEAALSELESAIKGDDKAAIEAKQQALLEASQKLMEIAQQQAQAQGAAGADAGQSSSSAKADDDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LIPA_PROM2
Sequence: MIKIYLDEADQSHLTSISKNAATKPEWLRVKAPQFERIGNTASLLSDLKLNTVCQEASCPNIGECFASGTATFLIMGPACTRACPYCDINFDRSKRDLDPTEPHRLAEAVSRMNLKHVVITSVNRDDLDDGGASQFFQCVSEVRKKSPETTIELLIPDLCGNWQALELVLDSKPNVLNHNIETVKSLYRKVRPQGNYQRTLDLLKRTKEYFPSVYTKSGFMLGLGESDDEVLNLLSDLKNHFVDIVTIGQYLSPGPKHLPVQRFVSPPKFTYFKLFGEDNLGFMQVVSSPLTRSSYHAEEIQKLMKKYPR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_LEGPC
Sequence: MYAVIKTGGKQYTVKEGDVLKIEMLPENVGNEIKFSEVLMLVDGDKVTCGTPFVAKATVKAEVLDHGRHKKVKIIKFRRRKHHMKQMGHRQYYSQVKITAIGK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HIS8_LACLM
Sequence: MSWQNNLRSVSPYIAGEQAELTDMIKLNTNENPYPPSLQVQKVIEDFKSDNLRLYPSTDAKVLRKALATYHHLNTDQVFIGNGSDEVLSLSFLTFFNSEKPLLMPDISYSFYPIYCGLYHIPYQKIPLADDFSLSVNSYFQENGGIVIANPNAPTGMAISLQEIEEILQNNQDSIVLIDEAYIDFGGESCLPLLEKFDNLVVVQTFFKSRSLAGIRLGVAFGSAEAIAHLYDMKNSFNSYPIDSLAQKIGEASLNDETYFQKSVSKIITTRENFKKELIKLGFQVTDSKTNFVFVHHPKVDATTLFKALYEAKIIVRHWNQARISDWLRITIGTDREMNTVIQFLKEYLKNKEKSY
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: NRDR_CLOD6
Sequence: MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIETTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEIETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS19_STRPG
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DAR1_ARATH
Sequence: MGWLTKILKGSSHKFSDGQCNGRYREDRNLEGPRYSAEGSDFDKEEIECAIALSLSEQEHVIPQDDKGKKIIEYKSETEEDDDDDEDEDEEYMRAQLEAAEEEERRVAQAQIEEEEKRRAEAQLEETEKLLAKARLEEEEMRRSKAQLEEDELLAKALQESMNVGSPPRYDPGNILQPYPFLIPSSHRICVGCQAEIGHGRFLSCMGGVWHPECFCCNACDKPIIDYEFSMSGNRPYHKLCYKEQHHPKCDVCHNFIPTNPAGLIEYRAHPFWMQKYCPSHERDGTPRCCSCERMEPKDTKYLILDDGRKLCLECLDSAIMDTHECQPLYLEIREFYEGLHMKVEQQIPMLLVERSALNEAMEGEKHGHHHLPETRGLCLSEEQTVTTVLRRPRIGAGYKLIDMITEPCRLIRRCEVTAILILYGLPRLLTGSILAHEMMHAWLRLNGYPNLRPEVEEGICQVLAHMWLESETYAGSTLVDIASSSSSAVVSASSKKGERSDFEKKLGEFFKHQIESDSSSAYGDGFRQGNQAVLKHGLRRTLDHIRLTGTFP
What is the function of this protein?
Acts redundantly with DA1 and DAR2 to regulate endoreduplication during leaf development.  Together with DA1 and DAR2, modulates the protein stability of the transcription factors TCP14 and TCP15, which repress endoreduplication by directly regulating the expression of cell-cycle genes.
What are the official names of this protein?
Protein DA1-related 1.
Protein: AAAP_ANAML
Sequence: MGCPVSRGGSPGCGRRIAEELRFFVVDREASMCGDSCNGGGDRQQRQELAAAARASLLCLGGVMQQHITAAKARAELRKELDAIDAEWRPVIARESLRKELKAIDAQWQHAITFLRISRAIVVSIELSKELKAIDAGWEPVIIHEAQKKKREREERVAQVRRELRAELRAIDAEWRLVIARESLRKELDAIDAECRHTIKLRSALRAIEGRMELSKELKAIDAEWRPAIRLESAYRAIIGSIELSKELKAIDAETQHAVELRRALRTIEGRIELSRELKAIDAEWAPRIAQAELAAAADALKRAADKLQALGKMDTTSTPGTDLIGVVTTAIATLAAAGMQPAPSTALTGVAAEVATPSTALGV
What is the function of this protein?
Associates with actin filament appendages that are formed in the inclusion appendages of the parasitophorous vacuole during infection of the host erythrocyte.
What are the official names of this protein?
Appendage-associated protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CSLG2_ARATH
Sequence: MEPQRKHSTALHTCHPCRRTIPYRIYAVFHTCGIIALMYHHVHSIVNANNTLITCLLLLSDIVLAFMWATTTSLRLNPIHRTEYPEKYAAKPEDFPKLDVFICTADPYKEPPMMVVNTALSVMAYEYPSHKISVYVSDDGGSSLTLFALMEAAKFSKHWLPFCKNNNVQDRSPEVYFSSKSHSSSDEAENLKMMYEDMKSRVEHVVESGKVETAFIACDQFSCVFDLWTDKFTRHDHPTIIMVLQHNETEMMPNLIYVSREKSKVSPHHFKAGALNTLLRVSAVMTNSPIILTLDCDMYSNNPTTPLHALCYLSDPKINFDLGFVQFPQKFQGVNKNDIYASELKRPFDINTVGFDGLMGPVHMGTGCFFNRRAFYGPPTTLILPEIETFGPNRIADKPIKAQDILALAHDVAGCNYECNTNWGSKIGFRYGSLVEDYFTGFMLHCEGWRSIFCSPTKAAFYGDSPKCLTDVIGQQIRWSVGLLEVAFSRYNPLTYGIKPLSLLMSLGYCHYAFWPFWCIPLVVYGILPQVALIHGVSVFPKASDPWFWLYIILFLGGYAQDLSDFLLEGGTYRKWWNDQRMWMVRGLSSFFFGFTEFTLKTLNLSTQGYNVTSKSNDDNEQMKRYEQEIFDFGPSSSMFLPITTVAIMNLLAFMRGLYGIFTWGEGPVLELMLASFAVVNCLPIYEAMVLRIDDGKLPKRICFLAGLLSFVLTGSGYFFLK
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein G2, AtCslG2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like G subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: PEBB_CAEEL
Sequence: MKRTTTDQQSSFQTDYFLTQLSHFTEAKFSLFEHAPLSERRERFRVHVERDEMPLTFCKTGINIPVKLEWSQTNGNEISFRSRPLVFNGIWVKVIGAMNSESLEGRVRFERFQREKRDRVISETFVFPEVEEEPIGLTDAEIAALRRDGLPI
What is the function of this protein?
Transcriptional cofactor (PubMed:17933794).  Required for controlling cell proliferation in the seam cells, a stem cell-like lineage, acting in concert with Runt-related transcription factor 1 rnt-1, perhaps by repressing expression of cyclin-dependent kinase inhibitor cki-1 (PubMed:17933794).  Represses expression of rnt-1 (PubMed:18158917).  Regulates male tail development (PubMed:17933794).  May play a role in vulval and/or uterine morphogenesis (PubMed:17933794).
What are the official names of this protein?
Core-binding factor subunit beta homolog bro-1, BROther (Drosophila tx factor partner) homolog.
What is the protein family that this protein belongs to?
Belongs to the CBF-beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THIE_ANADE
Sequence: MPVSEASVSAGRRARLGGLYVIVGGADPVAQARAAIGGGARAIQVRMKDAPAGAVLEATRRILALATGRALVLVNDRADLALLAGADGVHLGDDDLPVPEARRLLGPDLLVGRTTRTLEEARAALAEGADHVGYGPIFASRSKALPVPPRGLAALAEVARALPAPVVAIGGIGLDDVAAVARAGAACAAVIEAVLGAADPEAAAARMQAAFEAGRAARGATP
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ACDH_ALBFT
Sequence: MSKKIKCALIGPGNIGTDLLYKLRRSPVLDPVWMVGVDPTSEGLKRARELGLKTTEQGVDGLLPHVLADGVQIAFDATSAYVHAENSRRLTELGVLVIDLTPAAIGPFCVPPVNLLALVGRRVMNVNMVTCGGQATIPMIAAISRVQPVRYGEIVATISSKSAGPGTRKNIDEFTRTTSRAIEQVGGAAKGKAIIIINPAEPPLVMRDTVHCLTETEPDQAKITASIHAMIKEVQKYVPGYKLVNGPVFDDKRVSVFLEVEGLGDFLPKYSGNLDIMTAAAARTAEMFAEEILAGRINLQPMATVA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: SPT5_CANGA
Sequence: MSDGSVEPVKADDAVVDSSKRTHEEMSAENTEPVSEQAHGTGSENGDGENSLENSLEKDNAEKDNAESEKGSPSVTETAADDDSSKTDGNGEENQDAEGLAEDYDEEDFDEDEDDEDEEPAAKRRQQERNRFLDIEAEVSEDEEDEEDEEDSELVREGFITHGEDEDDEEGVAGNRRGDRLHRQLDQDLNKSSEEDAQRLAKELRERYGRSSSKQYRAAAQDGYVPQRFLLPSVDTATIWGVRCRPGKEKELVRKLLKKKFNLDRAMGKRKLKILSIFQRDNYTGRIYIEAPKQSVIEKFCNGVPDIYISQKLLIPVQELPLLLKPSKSDDVALEEGSYVRVKRGIYKGDLAMVDQISENNLEVMLKIVPRLDYGKFDEIDPVTQQRKSRRPTFAHRPAPQLFNPTMALRLDQANLYKRDDRHFTYKNEDYIDGYLYKSFRIQHVETKNIQPTVEELARFGSKEGAVDLTAISQSIKKAQAAKVSFQPGDRVEILNGEQRGSRGIVAKSTTTIATVNLPEFPLKPLEFPVSALRKIFEPGDHVMVINGEHQGDAGLVLTIKQGQVTFMSNQTREEVTITANNLSKSIDSTPTSSEYSLHDIVELSAKNVACIIQAGHDIFKVIDETGKVSTITKGSILSKINTSRSRLTTVDSSGNEIKIGDSIVEKIGARREGQVLYIQSQQIFVVSKKIVENAGVFVVNPVNVEAIASKDNMLNNKLDLSKMNPDIISKMGPPKSSMPSAAPVRTGREVALGKTVRVRSAGYKGQLGIVKDVNGDKATVELHSKNKHITIDKRKLTYYNREGGEGITYDELVNRRGRLPQARMGPSYVSAPRHMASGASGVVADNNGALAGGMTPGWGAFDGGKTPAVNSHGAGTSGATSAWGGASTWGGQGAGGSSTWGGQGGATSTWGGQGATSTWGGASAWGNKSSWGGASTWAASGEANGGVSTWGGGDRSTYGGASTWGNNATGGTSTWGGNNQEQNNGGNRSAWKDQGNKSNYGGGSSWGNQ
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT5, Chromatin elongation factor SPT5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_SPIMX
Sequence: MSPQTETKAGAGFKAGVKDYRLTYYTPEYETKETDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGYQVERDKINKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAEYAKELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMQAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERQVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGRVANRVALEACVQARNEGRDLAREGNEVIREACKWSPELAAACEVWKEIKFEFDTIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL7_PELPB
Sequence: MSIETLVEEIGKLTLTEASELVKALEEKFGVSAAPVAVAGVAAAAAGDAPVVEEQTEFDVVLTAAGESKINVIKAVRAITGLGLKEAKDLVDGAPKTVKEAISKDEAEKIAKELKDAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UPPP_THEPX
Sequence: MELLIKAFIMGIVEGLTEFLPISSTGHLIIVGKFIHFTGNFATMFEIVIQLGAILAVVFYYRKKIFASLKNLKPGSWGFNLWFKIFIAFIPAAVIGLLTHKYIEEHLFSPFTVAIALIAGAIMMIVIEDTFGKRYKIDNMDKVDTKKSLLIGIAQVMSLFPGMSRSASTIMGGMLAGLSVKAAAEFSFFLAIPTMFAATTLSLLKGFSAMSLLEWQALAVGFITSFLTALFVVDKFLPYLTRHSLKPFAYYRLAVGVLMILLVAEKIVK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEXA_BURP0
Sequence: MIKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDAPHQLTLPHAALMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFSSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLKRRPGGVELIAENPDYENIFVKAGSAEFALEGIAVGLIRPGEF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SSUB_ZYMMO
Sequence: MEKISIQLSKLRKNFGTVEVLKDVDIAIPEGQFVALVGESGCGKSTLLRLISHLERPTSGQLLIDGKERRKINPSVRYLFQEARLLPWRSVLDNVRLGAKDRDKKTARESLESVNLLDKENEWPEILSGGQCQRVSLARALAGKPKILLLDEPLGALDALTRVQMQKLIESLWLEQKFTVLLVTHDVSEAVYLADRVIALEKGQIGLDREIPLPRPRVKDRHFACFENEILNFIMKNYYI
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNPA_BACCR
Sequence: MSIDMKKKHRIKKNDEFQAVFQKGKSNANRQFVVYQLDKEEQPNFRIGLSVSKKIGNAVVRNRIKRMVRQAITELKDEIASGKDFVIIARKPCAEMTYEEVKKSLIHVFKRSGMKRIKK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SYP_SHEB2
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWEKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGMMRSREFLMKDAYSFHLDVDTMNETYEAMYNAYSNILTRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPVPTEPRGAATEELRLVDTPNAKTIAELVEQFDLDITKTVKTLIVVGASEATPLVALIVRGDHELNEVKADKLDLVASPVEMAPEALIRDAIGAGPGSLGPIGLNIPIVIDHSVSVMSDFAAGANVDDKHYFGINWERDLPTAQVADIRNVVEGEPTPDGSGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIIWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLNEAGIDVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDIPFDQLLDFLKNAVKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_PECCP
Sequence: MNMSATLILAFGMSMDAFAASIGKGAVLHNPRFRDAIRTGLIFGVIEAITPLIGWALGFFASQYILEWDHWVAFTLLLILGGRMVVEGFKGSSDCRCEKVKNHSLALLVCTAIATSLDAMAIGVGLAFLQVNILHTAMVIGCATMIMVTLGMMIGRYIGPILGKKAEVMGGLVLIGIGCNILYEHLGYAA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.