PharMolix/UniProtQA huggingface dataset:
Protein: RL15_METEP
Sequence: MKLNEIRDNEGATKARMRVGRGIGSGKGKTGGRGVKGQKARSGVSIKGFEGGQMPLHRRLPKRGFNNIHAHDLNEVNLGRVQQAVDAGKLDANAAVTVEALVKAGIISRARDGVKLLGVGELTSKLSFEVTRASKSAIEAVEKAGGSVTTTFAAGVAHRGAAEGAVASA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PDXY_PSEPG
Sequence: MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRIGVNVWPLNTVQFSNHTQYGQWAGEVLAPAQIPALVEGISNIGELGHCDAVLSGYLGSAEQGRAILAGVERIKAVNPKALYLCDPVMGHPEKGCIVPPEVSAFLLEEAAARADILCPNQLELDSFCGRRAQSLEDCVNMARSLLKRGPQVVVVKHLAYPGRAEDQFEMLLVTAEHSWHLRRPLLAFPRQPVGVGDLTSGLFLARVMLGDSWVQAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVRFEAQLLAL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: SYE_KLEP3
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLQWDEGPYYQTKRFDRYNNVIDEMLEAGTAYKCYCSKERLEALREEQMANGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMAITHVIRGEDHINNTPRQINILKALNAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIEFFSLGAVSKSASAFNTDKLLWLNHHYINTLPAEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEIAQSCRYFYEEFAEFDADAAKKHLRPVARQPLEVVRDKLAAIVDWTAENVHHAIQATADELEVGMGKVAMPLRVAVTGAGQSRALDVTVHAIGKSRSVERINKALAFIAEREGQAS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_BRUC2
Sequence: MFVSTAFAQTATESQPASTAGEHGAADAVHTETGVAHDAGHGSGVFPPFDSTHYASQVLWLAITFGLFYLFLSRVVLPRIGGVIETRRDRIAQDLEQAARLKQDADNAIAAYEQELAQARSKAASIAEAAREKGKGEADAERASAEAVLESKLKEAEERIAAIKAKAMSDVGNIAEETTATIVEQLLGLTADKASVSEAVKAIRASNA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL30_NEIMB
Sequence: MAEQKKIRVTLVKSLIGTIESHRACARGLGLRRREHTVEVLDTPENRGMINKISYLLKVES
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TSSC4_MOUSE
Sequence: MAETEAGLEADEPTEDDTLPSDTVSLSDSDSDLSLPSGVEVQVLSPERLSEEGQEDSGPEDPPSPPTGTLTTAVQPFHLRGMSSTFSQRSHSIFDCLESAARQAPCSAPQTSVSDNGSFRRPVTPPSQTPARGLSRVHGNTGPTRVLPVPDYVSHPERWTKYSLEDVSEASEQSNRDAALAFLSSRSQVSHTDYVPSFNQDPSSCGEGRVVFTKPVRDSEARAERKRVLKKGVGSGAGGEAAVELAHLAGPEAEEWSGHQGQPEVVVPSEAAHPESSSGPIGVKAVGFHGSKKRSRDHFRNRDGNPGGPGSERGPSV
What are the official names of this protein?
Protein TSSC4.
What is the protein family that this protein belongs to?
Belongs to the TSSC4 family.
Protein: Y1485_STAHJ
Sequence: MKEHSFYQFALTVRGRKDSKGDLAEEIFNDLSFPKHEKDFNQLSDYIEMQSDISVPMSEFDDLYEEYIEWLKF
What are the official names of this protein?
UPF0346 protein SH1485.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: FMT_STRP7
Sequence: MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL34_HAEIE
Sequence: MKRTFQPSVLKRSRTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RLA2_CANAX
Sequence: MKYLAAYLLLVNAGNATPSAADVKAVLSAADIEVEEEKVEKLISESDGKNVEELIAEGNEKLSSVPSGAPAAAAGGASAAAGGEATEEAAEEEAAEESDDDMSFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-A, CaRP2A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: OR4CF_HUMAN
Sequence: MQNQSFVTEFVLLGLSQNPNVQEIVFVVFLFVYIATVGGNMLIVVTILSSPALLVSPMYFFLGFLSFLDACFSSVITPKMIVDSLYVTKTISFEGCMMQLFAEHFFAGVEVIVLTAMAYDRYVAICKPLHYSSIMNRRLCGILMGVAWTGGLLHSMIQILFTFQLPFCGPNVINHFMCDLYPLLELACTDTHIFGLMVVINSGFICIINFSLLLVSYAVILLSLRTHSSEGRWKALSTCGSHIAVVILFFVPCIFVYTRPPSAFSLDKMAAIFYIILNPLLNPLIYTFRNKEVKQAMRRIWNRLMVVSDEKENIKL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4C15, Olfactory receptor OR11-127, Olfactory receptor OR11-134.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H2A1F_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKPKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-F.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS4_PORGI
Sequence: MARYTGPKSKIARKFGDPIFGADKVLSKKNYPPGQHGNNRRRKTSEYGLQLREKQKAKYTYGVLEKQFRHLFHRAQRAKGVTGELLIQFLEARLDNVVFRLGIAPTRSAARQLVSHRHITVDGSVVNIPSYSVKPGQVIGVRERSKSLEVIADALTGFNHSKYPWMEWDQSSLSGKLLHMPDRTDIPENIKEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: S22AG_MOUSE
Sequence: MESCNVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFERWDSSRALSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPPVTERGASGRASLEDESGGSGRAPPEKNTEMENEIENMKVSNLGGF
What is the function of this protein?
High affinity carnitine transporter; the uptake is partially sodium-ion dependent.  Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa.  Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin.  The uptake of TEA is inhibited by various organic cations.  The uptake of doxorubicin is sodium-independent (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 16, Carnitine transporter 2, CT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane.
Protein: NHRF3_RABIT
Sequence: MASTFNPRECKLSKEEGQNYGFFLRIEKDTEGHLVRVIEKGSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNAVTLLVLDGNSYEKAVKKQVDLKELGQSRQEADLRDENVAPVMNGGVETWTQPRLCYLEKQGNSYGFSLKTVQGKKGVYMTDIIPQSVAMKAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGNRIVFLLVDKETEKRHSEQKIEFRREAASLKLLPHQPRIVEMKKGSSGYGFYLKAGPEQRGQIIKDIDSGSPAEAAGLKNNDLVIAVNGKSVEALDHDGVVELIKKGGDQTSLLVVDKEADSMYRLAHFSPFLYYQSQELPNGSVTEVAAPTPVPPEVSSPDPTEEVEDHKPKLCRLDKGENGYGFHLNAIRGLPGSFVKEVQKGSPADLAGLEDEDIIIEVNGVNVLDEPYEKVVDRIQSSGDNVTLLVCGKKAYEYFQAKKIPIVSSMALPLAIPADSQGMLAELEYNLHEAKERAHSTASNSSSNSEDTEL
What is the function of this protein?
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains.  May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades.  In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins.  May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1.  May potentiate the CFTR chloride channel activity.  Required for normal cell-surface expression of SCARB1.  Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1.  Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney.  May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
What are the official names of this protein?
Na(+)/H(+) exchange regulatory cofactor NHE-RF3, NHERF-3, CFTR-associated protein of 70 kDa, Na(+)/H(+) exchanger regulatory factor 3, PDZ domain-containing protein 1, Sodium-hydrogen exchanger regulatory factor 3.
What is the protein family that this protein belongs to?
Belongs to the NHER family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cell membrane. Note=Associated with peripheral membranes. Localizes to the apical compartment of proximal tubular cells and to sinusoidal liver membranes.
Protein: FBX5_MOUSE
Sequence: MSRRTCSDLRRPSSCPCRLGARTTVDGCKEESPVLSVTMKCFNCNPDLSELEVVKPEDSGIEASYSPVCLEPSCNDCVRNHERLSFIDSPIVGHDNKENQRVQNTLDSSNETEELEASRLYEDSGYSSFTQSDRDDGILILENFRNSPQARLLPSQSPDQHPNKTLLPVLHFERVVCSTLKKNGKRNPKVDREMLKEVIASGNFRLQNIIGKKMGLEHLDILAELSRRGFVHLLANILTKLSGMDLVNLSKVSRIWKKILENNKGAFQLYSKTMQRVIESSKLSLHATTRGYVVGRAALTCVQKSSTWAPPKKDVQIKSSSQRGQRVSTYSRHNEFVEVAKTLKNNESLKACVRCNFPAKYDHYLERAVCKRESCQFEYCTKCLCAYHNNKDCLNGKILKASCKVGPLPGTKKSKKNLQRL
What is the function of this protein?
Regulator of APC activity during mitotic and meiotic cell cycle (PubMed:17190794, PubMed:15526037, PubMed:16809773).  During mitotic cell cycle plays a role as both substrate and inhibitor of APC-FZR1 complex (PubMed:16809773).  During G1 phase, plays a role as substrate of APC-FZR1 complex E3 ligase.  Then switches as an inhibitor of APC-FZR1 complex during S and G2 leading to cell-cycle commitment.  As APC inhibitor, prevents the degradation of APC substrates at multiple levels: by interacting with APC and blocking access of APC substrates to the D-box co-receptor, formed by FZR1 and ANAPC10; by suppressing ubiquitin ligation and chain elongation by APC by preventing the UBE2C and UBE2S activities.  Plays a role in genome integrity preservation by coordinating DNA replication with mitosis through APC inhibition in interphase to stabilize CCNA2 and GMNN in order to promote mitosis and prevent rereplication and DNA damage-induced cellular senescence (By similarity).  During oocyte maturation, plays a role in meiosis through inactivation of APC-FZR1 complex.  Inhibits APC through RPS6KA2 interaction that increases FBXO5 affiniy for CDC20 leading to the metaphase arrest of the second meiotic division before fertilization (PubMed:15526037).  Controls entry into the first meiotic division through inactivation of APC-FZR1 complex (PubMed:17190794).  Promotes migration and osteogenic differentiation of mesenchymal stem cells (By similarity).
What are the official names of this protein?
F-box only protein 5, Early mitotic inhibitor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle.
Protein: NDK_CAPAN
Sequence: MEQTFIMIKPDGVQRGLVGEIIGRFEKKGFSLKGLKLITVDRAFAEKHYADLSAKPFFNGLVEYIVSGPVVSMVWEGKGVLTTGRKIIGATNPLESAPGTIRGDYAIDIGRNVIHGSDAVESARKEIALWFPEGVAEWQSSLHCWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: TCSA_EMENI
Sequence: MLLNGQISALSLDDNDNGQQHQDEVQAKHQDQGHTCPSRPSVPSLSRIYRCTPVPTIVLDASMVIIEVSNSHVALFGKPRDSLLHTSISDVSPECIPVPNIPILYGALRAACSTREIQVVEHVVVGEKIAHNLRVTPVYEDETLLFVVLEVENLRAEVINNQHAYMNETYKILVDTVKDYAIFMLDPTGHIATWNAGAGVLKGYKAEEIIGKHFSILYSPADRDNGKPARALDVCLREGRIEDEGWRYRRDGSRFWANVLITPIYQFGQHVGFVKVTRDLTERKEAEACMIAAFEESSRLKTDFLANISHEIRTPMNGMQIALTMLTDTGLSEEQREHANIVQDSMSLLLQIVNDVLDYSKLSSGSFSLHADMLDIREIVGAVVRNCRSSLQEGVELDTEISPKLPTRMRGDPLRYRQVLQNLVGNAVKFTEKGSIHVKITSSTDEEDSDSSVVRTEVTDTGIGVPDSAINTLFTPFSRFANSAARKYQGTGLGLSICKSLAELMDGSVGYSPNPNASGSVFWFTAKMGGRSVTPPSKSPSVSGSPVPTEVASEMRSIAPRKHVLLVEDNIVNHTVMLKLLHTIGFQRIDGAWNGAEAVRMVRQKPLSYDIILMDVSMPVLDGLAATEQIRDMGLTMPIIAITGNAMKGDAETYIAQGMDDCICKPVHRDQLLRVLWKWFGT
What is the function of this protein?
May be part of a two-component regulatory system required for formation of conidia on certain growth media.
What are the official names of this protein?
Two-component system protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_COXB1
Sequence: MKSNDKVIIGRLARPYGLRGWIKVVSFTHPIDNLLNHPTWQIQHNNEWQPLKLQAGKLHEPFLVVKLENIDDPETAKHYTNDLIAIERGALGALKEGDYYWTDLIGLAVVNTHGIELGTVDSLIETGSNDVLVVRSKERERLIPYTSYTIQSIDLEKKIIVVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSLBB_XENTR
Sequence: MRLIQNMCTITEYPPGTHTECASSSAGTASSRVIKIAVVGGSGVGKTALVVRFLTKRFIGDYERNAGNLYSRQVQIDGMNLAIQVQDTPGVQINDQNLDSNEQLNKSLRWADAVVIVFSITDCKSFDLISRLHQHARQLHPDNRIPIVIVANKADLLHLKQVEPQHGLQLANMLGCTFYEVSVSENYIDVYNAFQVLCKEISKQQNTGTPERRKNSLIPRPKSPNMQDLKRRFKQALSAKVRTATSV
What are the official names of this protein?
Ras-like protein family member 11B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
Protein: RS2_CROS5
Sequence: MAVVSLEDLLNAGVHFGHQTRRWNPKMSQYIYTARNGVHIIDLVQTAQLMEDAYQYVRNNADKGKRFLFVGTKRQAAGIIAQEASRCGANYVNQRWLGGMLTNWETIKTRVERLKELEAMEESGQIARRPKKEASVLRRELGKLQKYLGGIKTMRRPPDVVVIVDQRREYNAIQECQKLGIPMISLLDTNCDPDYADIPIPANDDAIRSIKLILGKLADAIYEGRHGQLDSDDDYEEFDESLAEGDYDDYDEEEDEDSETVSSQEGEEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS2_HAMD5
Sequence: MVAISMREMLEAGVHFGHKTRYWNPKMKPFVFGSRNGIHIINLEFTVTMLNNALSELRKISARKGKILFVGTKRAASEAIKEAAGNCAQFFVHHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELNKLENSLGGIKNMGGLPDALFVIDANHEHIAVKEANNLGIPVFSIVDTNSDPDGIDFIIPGNDDAIRSIKLYLNAVSAAISEGRSENSVMQKEESLIETK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PYRC_ECO57
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILHAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEHQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: ALPH_SYNE7
Sequence: MKIKLLCISLAVLFCSSANAQKKQAKVQPSVFPQTVARPKLVVGMVIDQMRWDYLYRFYARYGNGGFKRLINEGFSAENTLIPYTPTLTACGHSSIYTGSVPAINGIIGNNWFDPQLGRDVYCVEDKSVKTVGSSSNEGLMSPKNLLVTTVTDELRMATNFRSKVISVSIKDRGAILPGGHTANGAYWYDDMTGSFISSTHYMQQLPTWVNDFNAQRLPNKYFEQDWNTLYPIETYTESTADAKPYERTFKGAKTSSFPHLFKQYANKNYSMMASMPQGNSFTLEFAKAAIPAEKLGQTGNTDFLAVSLSSTDYVGHQFGPNSIELEDTYLRLDKDLEDFFNYLDKTIGKGNYLLFLTADHGATHVPGFLRNKMPGGRLLLKVQTDLDSLIFNEFKVRCNFTIINNQVIFDTDAIKEAKADYAKIKQSTIDYLVKQDGVLNAVDIKNMGAVTIPQEIKNKIINGYNARRSGDVYIILDAGWYPTLTPGTGHAAWNPYDSHIPALFMGWGVKPGKTNKEYYMSDIAPTVSALLHIQQPSGSIGKVITDLLK
What is the function of this protein?
Alkaline phosphatase with broad substrate specificity.
What are the official names of this protein?
Alkaline phosphatase PhoV, APase PhoV.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side. Cell inner membrane; Peripheral membrane protein; Periplasmic side. Note=Associated with the periplasmic side of the inner membrane.
Protein: PA2AE_NAJOX
Sequence: NLYQFKNMIKCTVPSRSWLDFANYGCYCGRGGSGTPVDDLDRCCQIHDNCYNEAGKISGCWPYFKTYSYECSQGTLTCKGDNNSCAASVCDCDRLAAICFAGAPYNNDNYNINLKARCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 E, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL24_SHEWM
Sequence: MAAKIRREDEVVVLAGKDKGKRAKVSQVLPTGKLIVEGVNLVKKHQKPNPQLGVAGGIVEQEAPIQASNVAIFNSATGKADRVGFRLEDGKKVRFFKSNSELVK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TAL_LACP7
Sequence: MKFFIDTANVEEIKKANDMGVICGVTTNPSLIAKEGRDFKEVITEITNIVDGPISGEVKATTEDAESMIKEGREIAKIHPNMVVKIPMTVEGLKATKVLSQEGIKTNVTLVFSANQALLAARAGATYVSPFLGRLDDISTPGIDLIRTISDIFEIYNLPTEIIAASVRNPVHITDCALAGAHIATVPYSVIVQCTKHPLTDAGIEKFKADYRAVFGE
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MZM1_YEAS7
Sequence: MSTRTKALNAYRHGLRATRIAFRNDAEVLLAARAKMRSGMLCPPDPKLTTEDQIQHLEDVAVFLRRNLVQGKKVDGSSTKEPRYHLNIHKDTELGDNETIADPTARVKTNLKARPFKCSDKKQ
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial, Altered inheritance of mitochondria protein 8, Found in mitochondrial proteome protein 36.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PBX2_MOUSE
Sequence: MDERLLGPPPPGGGRGGLGLVGAEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYPASQVESLRHSMGPGSYGDNIGGGQIYSPREIRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN
What is the function of this protein?
Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.  Activates transcription of PF4 in complex with MEIS1 (By similarity).
What are the official names of this protein?
Pre-B-cell leukemia transcription factor 2, Homeobox protein PBX2.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H2A2_YEAST
Sequence: MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTAKASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.