PharMolix/UniProtQA huggingface dataset:
Protein: EPSB_RALSL
Sequence: MTQNLPQPPAVNAPENELDLVRYLDVLVANRWLIAGIAAAVMLLGAAYAFLARPVYEADIMVQVEDNPNSAKSLLGDVSSLFDVKTDANAEIEILRSRMVVGKAVDNLHLYITAKPRYFPLIGAWISSRATRLSEPGLFGLGGYVWGTESIDVDGFDVPEALEGQPFKLIVLGNGRYRLENKSLDAPIEGVVGEPLEAKQSIGTIQLQVNNLTAKAGATFELERDSRLKTMEMLQDKLKIAEKGKQSGIIGASLDGTNPALTAAIMNQIATEYVAQNIKRKAEEAERSLVFLDGLLPQLKLELERAEMKYNEMRNLRGTFDLSEEGKAFLQESVTVETSLQELKQKRAELLTRFTSSHPGVQAIDQQISVMSGKVNSMTRRLKSLPNIEQDTVRLMRDVQVDNELYVSLLNDMQQLKLVKAGKVGNVRLVDGAAVPEEPVKPKKLTVTPLAGVLGVVLGVMAAFVRNALFGGITDPQDIEEHTGLSVYATVPLSDTQVDLSGQLTTRKRGQYLLARRVPDDPSIEALRSLRTALQFAMQDAGNNLVVLTGPTPGVGKSFVSANLAAVIATGGKRVLLIDADMRKGYLHQYFGKDRKPGLLDLLAGNRSIEQVVHREVVPGLDFIATGLFPHNPSELLLNPRMVELMDTFRSQYDLVLVDTPPVLAVADTAILAARAGLVLLVTRFERSTLGEIRETIKQLQHANVDVRGVVFNALDPNTYRYGYGSRYGRYRYVQYGYTSNSKPPEAESA
What is the function of this protein?
Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor.  May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the inner membrane or their polymerization.
What are the official names of this protein?
Putative tyrosine-protein kinase EpsB, EPS I polysaccharide export protein EpsB.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_BUCAP
Sequence: MFSNYKKKKKIYFSKMHGLGNDFMVIESIKQDFILTKSIIENLSNRNTGVGFDQLLLIEKSNNFKFDFHYRIFNANGNEVEQCGNGARCVGLFLFLKGLINKRKIMLSTNKKNISIKFMSDNNIQVNMNEPSFKLEEISISKKIVLNNFSVKLINKNLKCSLVSIGNPHCVIKVESINNAPVKKIGELLEKNSIFPQGINVGFMKVINKNHIQLRVYERDVGETQSCGSGACAAVAVGIAKNLLCDNVKVDLLGGNLIIKWKGFNYPLYMIGTACHIYDGYIYI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_BLOPB
Sequence: MAQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASARVFNIKTNFFDQVVTIHQKDIIHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTDFRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDDQGLIIRDGNQILVGGNNRYVSVCRKHFVEQLESPLSLTKRVYKNR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I23_CONIM
Sequence: MMFRLTSVSCFLLVIACLNLVVLTNACLRDGQSCGYDSDCCRYSCCWGYCDLTCLINGKRATFQ
What are the official names of this protein?
Conotoxin Im11.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TELO2_XENTR
Sequence: MAPVSTVVKNAISDLAKISDGERLREALLSLKSYLGTGENSAQTQETTEFNRNHYTPVLEFLVAQIGPQWLDLLTSERLELWDSFFLEGPPDQAFLVLMDSLGKTGPSIRLDRCVHVLERFLQRGALAEVIWEVCQQQLESNPTSVLHEAILGRISSLPDHLANCLQQHNKPLFYPKNYYPRLAGSIIRVLQMVSDALRDGKNCSISFASQVVGKVCMQGRQKELLSVLVPRLKSLVQSDCIWQRICWRLLESVPDRWMEPVLTGIVQTAPGAEVLSQLLGDLVVKNKRTQFLLTKKMLFLQYGLKKDALQSILGYLSLDASRRHLLVKVLRELLEVWSSGSVVKHSPHPQLLHVSRCLLICLGLLNKQEIESCKQDLLVSLTSGARNYLDSSVPTTRRMGMVVAECLSHHIDTEGPGLSFQYEEDEDTRDLKALLKPPHMVETDSADFVKRPVESSPSKSPLSSPEVREKSKVKVKADQASDSDLDSDDDLVPYDMSADTELKKSKAPAYIRDCIEVLLSDDVEKLEVTMASLATLIQANTLATKEVSMELAKILLHIDEKPSVARFTELRHAALVAVTVTDPVTVSQYLTSEFYSLNYSLRQRMDILDVLSSAAQSLSEKPSHETSAESGSVNTDPHSIRSTAWTSSEVPVNWRKVVEERIASKTRRFAKGHSAATPVPAPNRYHAVAGHFFFPLIQNYDRQIVTFDLLGEDRLVLGRMVHTLGILMHLTLNAPIASQMGKALLEFVWVLRSHTDAFVRQGLLFCISTVLLSVPWEHLMTDMAEEVVETQCWLAEVAERDSDDDCRRLALNGLFLMEKLRSNIQGNP
What is the function of this protein?
Regulator of the DNA damage response (DDR).  Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.  Promotes assembly, stabilizes and maintains the activity of TORC complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.  May be involved in telomere length regulation (By similarity).
What are the official names of this protein?
Telomere length regulation protein TEL2 homolog.
What is the protein family that this protein belongs to?
Belongs to the TEL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Nucleus. Chromosome, telomere.
Protein: SYP_BRUA1
Sequence: MRLSRYFLPILKENPKEAEIVSHRLMLRSGMIRQQSAGIYSWLPIGLKVLNKVCTIIREEQNRAGANEILMPTIQSADLWRESGRYDAYGKEMLRIQDRQKREMLFGPTNEEMVTDIFRSYVRSYKDLPLNLYHIQWKFRDEVRPRFGVMRSREFLMKDAYSFDLDYEGAKMAYYRMFVSYLRTFARVGLQAIPMRADTGPIGGDLSHEFIILAETGESQVYCDRAYLDLAVPGADTDFRNDAQLTDIVTRWTTPYAATDEMHDEADWAKVKPESQVSARGIEVGHIFHFGTKYSEPMGAKVQGPDGKEHLVSMGSYGIGPSRLVAAAIEASHDDAGIIWPKTIAPFGAGIVNMKPGDEGCDGVSEKLYEALTNAGVDPLLDDKDERPGAKFATMDLIGLPTQVIVGPRGVAAGEVEVKDRKTGERQSLGIKAAINMLTAQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX9A_URTGR
Sequence: MERILLCFIVATLVAISMANPRPISIDPPCWTCYYRDSSGNCAFDAIACGGARKRVPKPISIDPPCRTCYYRDSSGNCVYDAFGCGGARKRVPKPISIDPPCRTCYYRDSSGNCVYDAFGCGGARKRVPKPISIDPPCRFCYHRDGSGNCVYDAYGCGAVRK
What is the function of this protein?
Does not affect the ASIC3 channel.  Does not cause lethality or paralysis of noble crayfish (A. astacus) at a dose of 1 mg/kg.
What are the official names of this protein?
Precursor protein UG.
What is the protein family that this protein belongs to?
Belongs to the sea anemone structural class 9a family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: EFTU_HAEIG
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKHYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALQALNGVAEWEEKILELANHLDTYIPEPERAIDQPFLLPIEDVFSISGRGTVVTGRVERGIIRTGDEVEIVGIKDTAKTTVTGVEMFRKLLDEGRAGENIGALLRGTKREEIERGQVLAKPGSITPHTDFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMTVSLIHPIAMDQGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ5_DICDI
Sequence: MLQSLNRSVRYLSTSIGSRLYCSNTNQTTKNNTNASGVNDNQQTHFGFKTVNKEDKESMVKDVFDSVSSSYDLMNDVMSMGIHRLWKDELINTLNPTPGSHLLDVAGGTGDISFRFLDKIKTSPNYFPNINKSNNGGGEVLKSSSLPSSATVFDINQSMLNEGKKRGLNKGYTDQSDPSIDWVQGNSEQLPFKDNTFNCYTVSFGIRNCTNIDQVLREAYRVLKPGGRFLCLEFSQVPNPLLRFAYDQYSFNVIPIMGQLISGDRDSYSYLVESIRKFPDQETFVQMIQDAGFKQVTYKNLTFGICSIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ZIC2_HUMAN
Sequence: MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHGSQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Plays important roles in the early stage of organogenesis of the CNS.  Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets.  Its transcriptional activity is repressed by MDFIC.  Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline.  Drives the expression of EPHB1 on ipsilaterally projecting growth cones.  Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.  Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.
What are the official names of this protein?
Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus (By similarity).
Protein: TOLB_XANOM
Sequence: MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVSAVVGADLDRSGQFRTLPAAQIVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVEYELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKITGVRGAFWTRIAYVTASGKGGAMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGARELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQVAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAREGGRGVLYAVSSDARVRQRLVLADGDVREPAWGPYRTAH
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MGRB_ECO27
Sequence: MKKFRWVALVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CAS3_PSEAB
Sequence: MNILLVSQCEKRALSETRRILDQFAERRGERTWQTPITQAGLDTLRRLLKKSARRNTAVACHWIRGRDHSELLWIVGDASRFNAQGAVPTNRTCRDILRKEDENDWHSAEDIRLLTVMAALFHDIGKASQAFQAKLRNRGKPMADAYRHEWVSLRLFEAFVGPGSSDEDWLRRLADKRETGDAWLSQLARDDRQSAPPGPFQKSRLPPLAQAVGWLIVSHHRLPNGDHRGSASLARLPAPIQSQWCGARDADAKEKAACWQFPHGLPFASAHWRARTALCAQSMLERPGLLARGPALLHDSYVMHVSRLILMLADHHYSSLPADSRLGDPNFPLHANTDRDSGKLKQRLDEHLLGVALHSRKLAGTLPRLERQLPRLARHKGFTRRVEQPRFRWQDKAYDCAMACREQAMEHGFFGLNLASTGCGKTLANGRILYALADPQRGARFSIALGLRSLTLQTGQAYRERLGLGDDDLAILVGGSAARELFEKQQERLERSGSESAQELLAENSHVHFAGTLEDGPLREWLGRNSAGNRLLQAPILACTIDHLMPASESLRGGHQIAPLLRLMTSDLVLDEVDDFDIDDLPALSRLVHWAGLFGSRVLLSSATLPPALVQGLFEAYRSGREIFQRHRGAPGRATEIRCAWFDEFSSQSSAHGAVTSFSEAHATFVAQRLAKLEQLPPRRQAQLCTVHAAGEARPALCRELAGQMNTWMADLHRCHHTEHQGRRISFGLLRLANIEPLIELAQAILAQGAPEGLHVHLCVYHSRHPLLVRSAIERQLDELLKRSDDDAAALFARPTLAKALQASTERDHLFVVLASPVAEVGRDHDYDWAIVEPSSMRSIIQLAGRIRRHRSGFSGEANLYLLSRNIRSLEGQNPAFQRPGFETPDFPLDSHDLHDLLDPALLARIDASPRIVEPFPLFPRSRLVDLEHRRLRALMLADDPPSSLLGVPLWWQTPASLSGALQTSQPFRAGAKERCYALLPDEDDEERLHFSRYEEGTWSNQDNLLRNLDLTYGPRIQTWGTVNYREELVAMAGREDLDLRQCAMRYGEVRLRENTQGWSYHPYLGFKKYN
What is the function of this protein?
In this bacteria Y. pestis-subtype CRISPRs do not confer resistance to phage DSM3 or MP22, but instead are required for DMS3-dependent inhibition of biofilm formation and possibly motility.
What are the official names of this protein?
CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST.
What is the protein family that this protein belongs to?
In the central section; belongs to the CRISPR-associated helicase Cas3 family.
Protein: YFH7_CANGA
Sequence: MVDVNRLKEEVIASYREICKENYRLLVFIVGPPGSGKSTIAEKLKDAINTSYLDYLKEIDRKTLRCENYNHINIDQFVQGIEGETISSALEDERHENFDSVENVDFICKKKRLKDGSYTITGRGGQLNAIKVRQPTSQEKNLEGNTTIAEVLPMDGFHLSRECLDHFSDPQWAHLRRGSSLTFDSNNFLKLCEIMAKTSRIFPSIGYDGDDFTAFDAISSSFDCSVPSVEVPGFDHSLKDPQPSQHTISFKSRIVIFEGLYLLYNKENWSKIYNIVSNSNAKLFYKILACEDQIESRVAKRHLKAGLVASIEDGKDKFRKNDLLNARDVEKNSISSEDIRLIRND
What is the function of this protein?
ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.
What are the official names of this protein?
ATP-dependent kinase YFH7.
What is the protein family that this protein belongs to?
Belongs to the YFH7 family.
Protein: RL17_DROYA
Sequence: MGRYSRESDNVAKSCKARGPNLRVHFKNTHETAQAIKRMPLRRAQRYLKAVIDQKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAEANADCKGLDADRLVVHHIQVNRAQCLRRRTYRAHGRINPYMSSPCHVEVILTEKEEVVSKATDDEPTKKKLSKKKLQRQKEKMLRSE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ARLY_MYCBP
Sequence: MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAAEQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CHLPB
Sequence: MAQNRVSRLMQEDRKFLIAYYMPEFPLPGSTLPVLEALQKSGVDIIELGMPYSDPIGDGPVIQDAAHTAIGNGVHIAGILDLVRKARAGEGCEKITVPLLLMGYCSPLIAYGGDCFLSDASEAGVDGLLIPDLPPEEAEDFLFRARGFGLSVIFFISPETPPERIGMIDGLSTDFSYCFAVNATTGTAKLAGADSERDIESYLRRVREHTKKKFVVGFGIKDRARVEKMWNLADGAVVGTALLQAIRNASTPEEVALMTAEFWKTLKS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CD70_MOUSE
Sequence: MPEEGRPCPWVRWSGTAFQRQWPWLLLVVFITVFCCWFHCSGLLSKQQQRLLEHPEPHTAELQLNLTVPRKDPTLRWGAGPALGRSFTHGPELEEGHLRIHQDGLYRLHIQVTLANCSSPGSTLQHRATLAVGICSPAAHGISLLRGRFGQDCTVALQRLTYLVHGDVLCTNLTLPLLPSRNADETFFGVQWICP
What is the function of this protein?
Cytokine which is the ligand for CD27.  The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses.  Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
What are the official names of this protein?
CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein.
Protein: FMT_MESFL
Sequence: MEKIKVIFCGTPQIGADILTTLTEMENVEVVLVISQPDRPVGRKKELKPTPVKEIALKNNLKIIQPVKISEAYEEIAQIESDFIVTCAYGQFVPTKILDLPKIDSINVHGSLLPKYRGGAPIQYAIKNGDSKTGISIMKMVKKMDAGDYYIQESIDIEETDDTGIMFEKLAKLGQKMIKENLLKIYNNELPPIAQNEDEVTFSKNISTEEEKINWNDLSVNVWNHIRSLSPWPIAHTFKGEERYKIQKVQILNNNVEAKPGTIVNISENGIDIQTKDGQVQILLIQKPGKKMMEASSYKLNNLSDLKVGDCFE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PHLC_TRYBB
Sequence: MFGGVKWSPQSWMSDTRSSIEKKCIGQVYMVGAHNAGTHGIQMFSPFGLDAPEKLRSLPPYVTFLLRFLTVGVSSRWGRCQNLSIRQLLDHGVRYLDLRMNISPDQENKIYTTHFHISVPLQEVLKDVKDFLTTPASANEFVILDFLHFYGFNESHTMKRFVEELQALEEFYIPTTVSLTTPLCNLWQSTRRIFLVVRPYVEYPYARLRSVALKSIWVNQMELNDLLDRLEELMTRDLEDVSIGGVPSKMYVTQAIGTPRNNDFAVAACCGACPGSHPDLYSAAKHKNPHLLKWFYDLNVNGVMRGERVTIRRGNNTHGNILLLDFVQEGTCTVKGVDKPMNAVALCVHLNTNQTARS
What is the function of this protein?
By hydrolysis of the attached glycolipid, releases soluble variant surface glycoprotein containing phosphoinositol from the cell wall of T. brucei after cell lysis.  It also cleaves similar membrane anchors on some mammalian proteins.  VSG lipase may play a role in processes such as parasite differentiation or antigenic variation.
What are the official names of this protein?
Variant-surface-glycoprotein phospholipase C, VSG lipase, Glycosylphosphatidylinositol-specific phospholipase C, GPI-PLC.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RRF_ESCF3
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: NDHN_SYNY3
Sequence: MLPLPLIANGKGFIRALENDGALAVYAPLEGGYEGRYQRRLRANGYASISLSARGLGDVEAYLMQVHGVRPAHLGKKNIAQEGAVGPIYFAQPIAGYQLENLPAQSKGLVLWILEGYILSQTEIQDLISLTKRVPKLKVVLEMGGDRVFRWQPLLDCLQAA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UBIE_CERS1
Sequence: MSDETSNTTHFGFRTVPEGEKAGMVHGVFTRVASKYDIMNDLMSGGVHRLWKDAMMDWLAPRPGQKLLDVAGGTGDISFRFLKRAPGAEATVCDMTESMLVEGRQRADAAQMADRLDWVVGDAMALPFASNTFDVYTISFGIRNVTRVQDALNEAYRVLKPGGRLMVLEFSQLPNPMMQWAYDRYSFNVIPVMGQIVANDRDSYQYLVESIRKFPDQETFADMIRKAGFGLVKYRNLSLGIAALHSGWKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: YBI3_YEAST
Sequence: MVFPVPSAEEKCSAQCQSRQDYSIRSNRIQLHRRPIFKVPPLPVSILVSLDFAYTDLLVGNALLRWSHLVRLARVVLEFLSTKLTSKHAIVGIEYCSVASIGLDAAIWFGRPRQKPSSYHQLYGKKAQLKQMYKYHIIVLF
What are the official names of this protein?
Putative uncharacterized protein YBL083C.
Protein: TIG_RALSO
Sequence: MSTVIENLGKLDRKVTLAVPKAEVEQEKQSRLARLSKTVKMSGFRPGKVPMKMVEKQYGQQVEMEVRFDKAARQFFDITNEQGVKVAGQPRFELKSEGVADDQFAFDATFEVYPEVKIGDLAGAELTRTKTEITDAEIDKTIDILRKQRVHYHPRGEAGDHGDGGEAVAQNGDRVTVDFVGTIDGVEFAGGKAEGFGFVLGEGRMLPEFEQATLGLKQGESKVFPLAFPADYHGKDVAGKTAEFTVTLKQVEWAHLPEINGAFAQSLGIADGSLDKMRADIRENLEREVKRRTHALLKDQVMDALLKVAELDVPKSLIEQDQERLVEMARRDLEARGMPNVKNMPIPAEMFAQQAERRVKLGLVLAEVVKVNALEAKPEQIKAEIEEFAKSYEDPKEVIRWYYGDQQRLAEMEAYVLENNVVNFVCDKAKVADKAMSFEELTATQGAQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GCST_CHICK
Sequence: MLRAGCRAALARRHLSSAPEGLKQTPLDALHRARGGRMVPFAGWSLPVQYGRGHLESHLHTRRHCSLFDVSHMLQTRVYGRDRVRFLESLVVGDIAELRPGQGTLTLLTNERGDIVDDLIVTNTAEDHLYVVSNAGCADKDRAVMEGRAAELRAAGGDVHLEVSGQRAAGVQGPSMAQVLQAGLPDDLTKLTFMTSTATTVFGVPGCRVTRCGYTGEDGVEISVPAGRAVELAERLLGCPEVWPAGLAARDSLRLEAGLCLYGNDIDESTTPVEAGLLWTLGKRRRTAMDFPGAAIIMEQVKEKPKRKRVGLTSVGPPLRPPAAILGPEGTPVGTVTSGCPSPSLGKNIAMGYVQAAHSRPGTTLTVEVRKKQHPALVTKMPFVPTHYYMAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APT_SALNS
Sequence: MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYELEYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFDLGGEQRLEKQGITCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_MICAN
Sequence: MASGNPNQPISYPIFTVRWLAVHTLAVPTVFFIGAIAAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.