PharMolix/UniProtQA huggingface dataset:
Protein: GYRA_BRAHW
Sequence: MAVKKNKEDNSEERQYSTLTKDILKRVDHISIENELRESYLTYAMSVIVSRALPDVRDGLKPVHRRILYAMYDANLTHDKPYKKSAATVGEVLARYHPHGDAAVYGTMVRMAQDFSMRYLLVDGQGNFGSIDDDPPAAMRYTEARMTRFAEEMLNDIEKETVKFVPNFDDSRTEPSVLPATVPQLLVNGSMGIAIGMATNMPPHNLKEVVNAIVYYIDHQDAEIKDLMRYVQGPDFPTAGIIYGKEGIKEAYTTGKGRIKLRARLEVEETKRDREAIVVKELPYGVVKTTLHEKIADLVKQGKIEGVADIRDESSNRAGIRLIIELKKGVATQIVLNQLWKHTDLETTFGIINLALVNGEPKVLNLKELIKYFVDHRVEVITKRTEYDLNQAKAKAHILEGLLIAQANIEEVIRIIRESENTDAARTTLMNRFKLSEKQAQAILDMPLKRLTALEKLKIEQELQQLREFIAYCEDLLAHPEKILAVIKDELKKISEKYGDDRRSEIIGKTNDTEIDEEDLIHDEDVAVSITTQGFIKRVPASSYRTQGRGGVGVQGGKSQGEHYIEHLFVASTKDYLFIFTDRGKAFWMKVHEIPALSKISQGKSIKFILNLAPEEKITSYFTVSEFDPKQSIIMVTKMGTIKKMELKHLENAKKRGILALTLENNDELVAVSPVQTGDDFIMTTAAGLALRITEEKIRKMGRAAAGVKGISLDDDDICVSGNAIHKGESLIVITENGIGKRLSSKQFNVKGRGGKGQIYIKPDNKTGNVVSVKTVGDKDEIMVVTTDDMTIKIKADSIPELGRNAKGVKIVNISDGARVSDLAVVPADNEEKK
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_STRE4
Sequence: MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHLDIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIRSLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQYPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSISESSYPQAIYDRVERFLKEP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CATV_NPVAC
Sequence: MNKILFYLFVYGVVNSAAYDLLKAPNYFEEFVHRFNKDYGSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPIQTQNFCKVIVLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLASLESQFAIKHNQLINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYITVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIKYCFNSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVIY
What is the function of this protein?
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus.  Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteolytic cleavage upon cell death.
What are the official names of this protein?
Viral cathepsin, V-cath, Cysteine proteinase, CP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum. Note=Retained in the host reticulum by its interaction with chitinase/CHIA.
Protein: TIN1_HOPTI
Sequence: FCTMIPIPRCY
What is the function of this protein?
Antibacterial activity against B. subtilis, E. coli, S. aureus, M. luteus, P. putida and S. cerevisiae.
What are the official names of this protein?
Tigerinin-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_FRATM
Sequence: MKTFTAKPSNIKREWLLIDATDKTLGRLATEVAMILRGKNKPEYTPHMDTGDYVVIVNAEKVAVTGNKRKAKTYYHHTGYIGGIKSVSFEKLIATHPERAIEKAVRGMLPRTPLGRTMFKKLKVYAGEAHPHTAQQPKAHNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RECX_ECOK1
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_PHOV8
Sequence: MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSENILLKAQEFGLHHIQLHGRETPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYFLFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGSLSLLLQFKHEQWAGIDLNSGFETAPALKDDAAVHTFINQLKQKIQ
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RPOE_HAEIN
Sequence: MAEQLTDQALVERVQQGDKKAFNLLVSRYQNKVAGLLTRYVSRNDIPDVVQESFIKAYRSIESFRGESAFYTWLYRIAVNTAKNYLTAQGRRPPNEDILAEDAENYDVGTHLRDVDTPENEMLSSELERIVFDTIHNLPEDLKTAITLRELEGLSYEDIAEIMDCPVGTVRSRIFRAREMIENKIQPLM
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma-E factor, RNA polymerase sigma-E factor, Sigma-24.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane via RseA.
Protein: ORN_SHELP
Sequence: MAADETNLIWVDLEMTGLEPEVDRIIEIATIVTDKELNILAEGPVIAIHQSEDVLAAMDDWNQKHHGESGLIDRVRASDFSEQDAIEQTIAFLSEHVPAGVSPMCGNSIGQDRRFLNRYMPTLEDYFHYRNIDVSSVKELVRRWRPEVMDGFKKQGTHQALVDIQESIAELRYYREKVFKI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFB_SHIB3
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYIHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_CALMQ
Sequence: MASSGRYKVKFRRRREGKTDYYKRRIMVISGKPRLVVRFSNRYVLAQVIVSAPQGDFTVAEASSRELVKKFGWLGGTGNTPAAYLVGLLIGYRALSKGIKLAVLDVGLHRVTKGGRLFAVVKGAVDAGLEVPHDEEVQPSEDRLNGEHIAQYAADLKQSNPELYKIRFSKYLARGLEPENISKHIEEVKSKIMEKYAKSEAKAEDSQ
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RHA3_RHOTO
Sequence: MVAYPEISWTRNGCTVAKYPEISWTRNGCTVSKYPEISWTRNGCTVA
What is the function of this protein?
Rhodotorucin-A is a mating pheromone in cells of mating type A of Rhodosporidium toruloides.
What are the official names of this protein?
Rhodotorucin-A peptides type 3.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RLMH_LARHH
Sequence: MKITLLAVGTKMPRWVDEAYADYAKRLPREVQLELKEIKPEKRGGGVTAEKGIAAEHARLMAALPPRAKLVVLDERGRNWTTMQLADNLKGWLADGQDIAIVIGGADGTAAELKSRADILLQLSAMTLPHGMVRVLLAEQVYRAVSILNGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_PSEFS
Sequence: MSALPPAIFLMGPTAAGKTDLAIELTKVLPCELISVDSALVYRDMDIGTAKPSKALLAQYPHKLIDIIDPAESYSAADFRTDALAAMAEITARGNIPLLVGGTMLYYKALQEGLADMPAADAQVRAELEEEAARLGWQALHDQLAAIDPVSAARIHPNDPQRLSRALEVWRVSGQTMTEHRLKQSAQSADAGASGQSQLPYTVANLAIAPANRQVLHERIAQRFTIMLEQGFVDEVVALRSRGDLHPGLPSIRAVGYRQVWDHLDGKLTSAEMQERGIIATRQLAKRQFTWLRSWSDLHWLDSLDSDNLSRALKYLGTVSILS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RPPH_ALISL
Sequence: MIDGDGFRPNVGIVICNSHGQVFWAKRYGQHSWQFPQGGIDDGETPEQAMYRELYEEVGLTKNDVRILASSRHWLRYKLPKRLVRWDSKPVCIGQKQKWFLLRLECDESKVNMQRDRSPEFDGWRWVSYWYPVRQVVSFKRDVYRRALKEFAAIAMPFKERKFKRKGKKG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: THSG_SACS2
Sequence: MAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITNDGATIVKNMEVQHPTAKLLIETAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVIIEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSSKFFSTEHTLEKIINLVIDASLAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLADFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIASYLMGKNGIMALKNVKRSDIELLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLFIQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLLEPYIVAGGGAVEEELAKRLRDDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTKARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit gamma, Chaperonin subunit gamma, Thermosome subunit 3.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: H2B_TRYCR
Sequence: MATPKSSSANRKKGGKKSHRKPKRTWNVYINRSLKSINNHMSMSGRTMKIVNSFVNDLFERIACEAATVVRVNKKRTLGARELQTAVRLVLPADLAKHAMAEGTKAVSHASS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LFTR_ALCBS
Sequence: MVPWLEPGEPFPDTRLALTDPDGLLAAGSDLSPDTLLRAYSTGIFPWYDAESQPILWWSPAPRCVIQLEQLHVSRSLARHLRRADFTVTFDRAFETVMRTCAAPRQDEAGTWISEDMLAAYCRLHELGYAHSVEIWQNGALAGCLYGIQLGQMFFGESMASPQRNGSKVALVALRNFARKLDIQLLDAQIENPHLMSMGAEMMPRSAFEAHLQRWIPSQPAPSHWPGDRFDWPDLQAAHQAF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELOV7_RAT
Sequence: MAFSDLTSRTVRFYDNWIKDADPRVENWLLMSSPLPQTIILGLYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGTGYSFRCDIVDYSQSPRAMRMVHTCWLYYFSKFIELFDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYFYYGLCAMGPAYQKYLWWKKHLTSLQLVQFVLVTVHIGQIFFMEDCNYQYPVFLYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTMENGNCKSKHH
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs.  Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA.  Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs.  May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase Elovl7, ELOVL fatty acid elongase 7, ELOVL FA elongase 7, Very long chain 3-ketoacyl-CoA synthase 7, Very long chain 3-oxoacyl-CoA synthase 7.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL7 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEUC_PSET1
Sequence: MAQTLYDKIWQAHTIASINEQTDLLYIDRHLVHEVTSPQAFAGLREKNRTVRCPEKTFATMDHNVSTKSRSLDAASEVSKNQLMALDANCKEFGIVLYDLNSINQGIVHVMGPEQGITLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLQQKKAKSLKIQINGRLRPTVTAKDLIMAVIGKLGTAGGTGYVAEFCGEGIEALSMEARMTLCNMSIEMGAKAGLIASDQITYDYLKGRPFAPKGADFDAAVKYWETLKTDDGAQFDHVVELEASSIQPQITWGTSPEQVIGVDECIPDPDKEPDLIKADAIRSALKYMGLKAGEKLSSAKVDTVFIGSCTNSRIEDLRAAAKIVEGKKVVAGIEALIVPGSGLVKKQAEDEGLADIFKAAGFEWREPGCSMCLAMNDDRLGAGKRCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAIHGHFVDIRGEA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GLGA_SULSY
Sequence: MKVVFVSSEIYPFAKTGGLADITGALPRKIASQGVKVFGFMPLYKTVDINKHGIIKIDASVDVNLNNRVYTFEVYKKIDDATFFFLKNDELFGRDYLYGPPEGDYPDNDIRFGSFCYAVMEFIKRENLNPDLIHVNDWQTALIPVLNYHKYNNHHVRTVITIHNLAYQGIFDKFAIERLNLGWDLFHMEALEYYDKVNFLKGGIVFSSAITTVSPTYAKEITFPEYGYGLDGVLRKYSNKLYGILNGIDYDVWNPETDKYIYENYCVFTIQKKSINKKLFLKEVGLKDEAKPLYIFIGRLAHQKGVDLIRDSIEEMSKMPANFAILGTGDKGYNDFFKSIEGKYENIFIKVDYNEAFSRKMYAAADFLLMPSLFEPCGLNQMIAMRYGTLVVARDTGGLKDTVKDVSQPDGYGILFKNPIKDEFLNALYRAVELYNNKKLFESLQKKVMEIDFSINNTAKKYIKLYESLKYSREVKI
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: DIPPS_PYRFU
Sequence: MNILGGEEVKGVILAAGYGSRMGEKPKGLLKIAGREILYRTIKNLEKNGIKEFIIVTNERYLQKFEEFVKENNLQNVKLAVNRFPEKGNGYSLYVAKDFVKGKFVLVMSDHIYEEKFYELALRGEGLIVDRNPKFVDIDEATKVKIENDRVVDIGKEIPSWDGVDTGFFILDDSIFSVIEDILKEKEVVELKDVVKRARLKVSYVDGLYWMDVDTPGDLKKARKLIVYSSVKGVGDGFISRYINRKISTRISALLVDHITPNKLTIVTFLFGIFSGLMNLISVPLAAILYQISSIFDGVDGEIARARMQTSKFGGFFDSILDRYVDFTYLLTLAYVTIREPIWWVIAGIAIFSSAMVSYSTERFRGAYCADAYKVVPALRKIPGKRDERIFVTMIFALLGLIKPLFALLAAWSTLRVIITIYLVWRDVNG
What is the function of this protein?
Involved in biosynthesis of di-myo-inositol phosphate (DIP), a widespread organic solute in microorganisms adapted to hot environments.  Catalyzes the condensation of CTP and L-myo-inositol-1-phosphate into CDP-L-myo-inositol, as well as the biosynthesis of di-myo-inositol-1,3'-phosphate-1'-phosphate (DIPP) from CDP-L-myo-inositol and L-myo-inositol-1-phosphate.
What are the official names of this protein?
Bifunctional IPC transferase and DIPP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPDF_TREPA
Sequence: MRRGGACVQKKEYLPLTSRQPGVCLLSEILVRALEARSFFLVVVTVPAGEVAYAESQVACDSRLSAFPSRTRPVILYVPGAHTRSASVRAGLDAMATHAPDVVLVHDGARPFVSVALIHSVLEATCRYGAAVPVIEATDTPKGVAADGSIETHLIRSRVRLAQTPQGFCYASLCAAHHRAATDGEQYTDDSELYARYGGTVHVCAGERSNVKITYPEDLEQRASEPALTRGISVLPCTEEGALRVGLGTDMHALCAGRPLILAGIHIPSKKGAQGHSDADVLAHASIDALLGAAGLGDIGTFFPSCDGRWKDAHSCALLRHTWQLVRAACWRLVNLDAVVCLEQPALHPFREAMRASLAQALDTHVTRVFVKAKTAERLGPVGSGAAVTAQVVVLLKKI
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: ATL75_ARATH
Sequence: MAANELASSSVQAFQEQSLGGFVSRKLLLHNPFDHNTQRAFAVAPSPLITHENNLSGNVLMLLSVLICGIICCLGLHYIIRCAFRRTSSFMISEPIAGLSTPCGSSNKGINKKALRMFPVVSYSPEMNLPGLGEECVICLSDFVSGEQIRMLPKCHHGFHVRCIDKWLQQHLTCPKCRHCLVETCQKILGDFSQADQVAATPTASVIVRIAPLEPEGRVNILRESS
What are the official names of this protein?
RING-H2 finger protein ATL75, RING-type E3 ubiquitin transferase ATL75.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LUXS_CAMC1
Sequence: MPLLDSFCVDHVKMKAPGVRLAKSMKTPKGDDISVFDLRFCKPNEEILPEKGTHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSVIGTPSEEAVKKAWLASMKDILEVKDQDKIPELNKFQCGTYKMHSLDEAHAIASKILAQGLVIINNDEIKLDVDAMGLKKH
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RL28_CHLTE
Sequence: MSKVCVLTGKRPKYGNNVSHANNHTRTRFEPNLHTKRIWIEEERRWVKVRLTAKAMKIMSKTGTAELAKLLK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: AROC_STREM
Sequence: MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANHVLVFGGIEVAVPEAMPFTDIKKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLDAKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL19_DEIRA
Sequence: MQTHIKINRGELLRGIEQDHTRQLPDFRPGDTVRVDTKVREGNRTRSQAFEGVVIAINGSGSRKSFTVRKISFGEGVERVFPFASPLVNQVTIVERGKVRRAKLYYLRELRGKAARIKSDRSRVMKDAARAQQDKANASASQAAAAQADVTVISAAPEVAPETQGE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity).  Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: C15A1_DIPPU
Sequence: MVIALIVIIIFLVCLDVIKPRGYPPGPVWLPVVGSYLWFRREKSRVGYYHLVWSSLSSRYGPVTGMRLGTDYIVVACGYDAIRDILLRDEFDGRPDGYFFRLRTFGKRMGVVFTDGPVWQEQRRFCMQHLRKLGLGSRSMEAHIEEEARDLVASLHRRSNGGLTAIPMHDVFDICVLNSLWAMLAGHRFDLDDQRLVDLLDIVHKCFRMIDPSGGLLNQMPPLRFIAPRHSGYTNLMTHLNRIWNFLRETIDDHRKSFNADNMRDLIDLFLREMETSKCQNNSSFEDLQLVSLCLDLFMAGSETTSNTLGFAVLYMLLYPQVQRRVQDELDRCVGTDRQPTLQDRRSLRYLEAVLMEIQRHATIAPSGIPHKALKNTVLMGHTIPKGTTVLVSMWSLHRDVQHWGDPEVFRPERFISGNGNIKQDDWFMPFGIGKRRCIGETLAKASLFLFFSTLLHNFSILPSSESPLPSLEGYDGVTLSPKPFSAKLIPRK
What is the function of this protein?
Catalyzes the conversion of methyl farnesoate to juvenile hormone III acid (methyl (2E,6E)-(10R)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate) in juvenile hormone biosynthesis.
What are the official names of this protein?
Methyl farnesoate epoxidase, Cytochrome P450 CYP15A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.