PharMolix/UniProtQA huggingface dataset:
Protein: NQRE_VIBAL
Sequence: MEHYISLLVKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGVAVVVVLTIAVPVNNLVYNLVLRENALVEGVDLSFLNFITFIGVIAALVQILEMVLDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESIVYGFGSGVGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OVAL_MELGA
Sequence: MGSIGAVSMEFCFDVFKELKVHHANENIFYSPFTIISALAMVYLGAKDSTRTQINKVVRFDKLPGFGDSVEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEETYPILPEYLQCVKELYRGGLESINFQTAADQARGLINSWVESQTNGMIKNVLQPSSVDSQTAMVLVNAIVFKGLWEKAFKDEDTQAIPFRVTEQESKPVQMMYQIGLFKVASMASEKMKILELPFASGTMSMWVLLPDEVSGLEQLETTISFEKMTEWISSNIMEERRIKVYLPRMKMEEKYNLTSVLMAMGITDLFSSSANLSGISSAGSLKISQAAHAAYAEIYEAGREVIGSAEAGADATSVSEEFRVDHPFLYCIKHNLTNSILFFGRCISP
What is the function of this protein?
Storage protein of egg white.  Lack protease inhibitory activity (By similarity).
What are the official names of this protein?
Ovalbumin, Egg albumin.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: T23O_PSEF5
Sequence: MSQCPFSSNPPAEWHNAELNFSDSMSYGDYLDLGRILSAQHPLSPDHNEMLFIIQHQTSELWMKLMLHELKAAREHVRQGQLPPAFKMLARVSRIFDQLVHAWAVLATMTPSEYKSIRPYLGQSSGFQSFQYREIEFILGNKSAALLRPHAHRPELLQSLEASIATPSMYDEAIALMARSGLSIDPARLALDSTTTTQHDPSVEAAWREVYANPSAYWDLYQLAEKFIDLEDSFRQWRFRHVTTVERIIGFQPGTGGTEGVGYLRKMLDTVLFPELWRVRSSL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: TLYA_MYCTU
Sequence: MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP
What is the function of this protein?
Acts as a host evasion factor, that significantly contributes to the pathogenesis of M. tuberculosis by modulating adaptive immune responses by inhibiting host-protective Th1 and Th17 cytokine responses as well as autophagy (PubMed:25847237).  Catalyzes the 2'-O-methylation at nucleotides C1409 in 16S rRNA and C1920 in 23S rRNA (PubMed:16857584, PubMed:20854656).  Is likely involved in ribosomal biogenesis (PubMed:21443791).  Also exhibits hemolytic activity in vitro, by binding with and oligomerizing into host cell membranes (PubMed:20854656, PubMed:9611795).
What are the official names of this protein?
16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA, 16S rRNA (cytidine1409-2'-O)-methyltransferase, 23S rRNA (cytidine1920-2'-O)-methyltransferase, Hemolysin TlyA.
What is the protein family that this protein belongs to?
Belongs to the TlyA family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, cell wall. Host cell membrane. Note=Can bind to target membranes such as macrophage phagosomal membranes (PubMed:20854656). In native and recombinant hosts (M.smegmatis and E.coli), M.tuberculosis TlyA can reach the bacterial surface in functional form and colocalizes with the HBHA protein which is known to be part of cell-wall (PubMed:26347855). TlyA does not seem to depend on either Tat or Sec pathways for translocation to cell-wall (PubMed:26347855). Appears to be capable of reaching the extra-cellular milieu using a vesicle mediated transport (PubMed:26347855).
Protein: UBXN1_HUMAN
Sequence: MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGLEGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS
What is the function of this protein?
Ubiquitin-binding protein that plays a role in the modulation of innate immune response.  Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways.  Following viral infection, UBXN1 is induced and recruited to the RLR component MAVS.  In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome.  This function probably serves as a brake to prevent excessive RLR signaling (PubMed:23545497).  Interferes with the TNFalpha-triggered NF-kappa-B pathway by interacting with cellular inhibitors of apoptosis proteins (cIAPs) and thereby inhibiting their recruitment to TNFR1 (PubMed:25681446).  Prevents also the activation of NF-kappa-B by associating with CUL1 and thus inhibiting NF-kappa-B inhibitor alpha/NFKBIA degradation that remains bound to NF-kappa-B (PubMed:28152074).  Interacts with the BRCA1-BARD1 heterodimer and regulates its activity.  Specifically binds 'Lys-6'-linked polyubiquitin chains.  Interaction with autoubiquitinated BRCA1 leads to the inhibition of the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer (PubMed:20351172).  Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
What are the official names of this protein?
UBX domain-containing protein 1, SAPK substrate protein 1, UBA/UBX 33.3 kDa protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHPD_CAUVN
Sequence: MSIEALRARLPDYAHDLGTNLALLVDDPALDPEARWGCFVASACAVGEPQTLRAIDAAATAAGLTAEANRAARKAAAMMAMTNVYFRAVHLMEGAAYQALPCRLRLNRLAHAGARGVTYDLSCVAVSAINGCGACLDSHEADLRGRGVEPTQIQAALRIAAVVSAVARTLAAEAALHPQNLEI
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: COBQ_RIPO1
Sequence: MKAIMVVGTTSHAGKSFITTAICRILARQGWHVTPFKGQNMALNAYVTPTGGEIGHAQAVQAWAAKITPSVDMNPILLKPQGNMTSQVIIHGQAVGTTSAQEYYEQYFDRGWKAITSSLDCLASEYDVVVCEGAGSPAEINLKHRDLTNMRVAHHLNAATILVVDIDRGGAFAHVVGTLQLLEPEEKALIKGIVINKFRGQRSLLDSGIEWLENYTSIPVLGVIPWREIMFPSEDSLGLLDRPSYRSTTSLKISILRLPHISNFTDFDPLDAETTVNLNYLDLRGTLGYPDAVIIPGSKTTIADLIALHTTGMAQQLQDYVSAGGVILGICGGFQMLGQTVFDPDQLEGGQKAYKGLNLLPLETIITSNKIVRQRQIMSNYPYSGLPVTGYEIHQGITQLIQSYETEQTILLDQLFDDISLGFVNESQTIWGCYLHGLFDNGAWRRSWLNYLRQRRGLPSLPTGIANYREQREANLDAIADLVEEFVNLKPVFPK
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: GATC_STRMU
Sequence: MKISEEEVRHVANLSKLKFSDDETTEFATTLTKIVDMVELLNEVDTQGVPFTSNVADNINYMREDVSVAGWDREQLFKNVPEHEDGLIKVPAIIDEGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: EX7S_VIBCH
Sequence: MASKKPENMSFESTIEELEQLVEQLESGDLALDEALRKFERGISLARAGQLKLDDAEQRVRILLSNSDDAPLSDFSDVAE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PROMM
Sequence: MTERFNDRLADVIRRPLITEKATSALEQNQYTFEVDHRAAKPDIKAAVEQLFDVRVVGISTMNPPRRSRRVGRFTGKRAQVKKAIVRLAEGNTIQLFPES
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: AL5AP_RABIT
Sequence: MDQEAVGNVVLLAIVTLISVVQNGFFAHKVEHESRNQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSLAGILNYCLILLFGSDFENYIKTISTT
What is the function of this protein?
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase).  Anchors ALOX5 to the membrane.  Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5.  Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).
What are the official names of this protein?
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLYA_NITHX
Sequence: MNSSAKTASAPDSFFTATLAEADPEIAAAIKGELGRQRHEIELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGGCEWVDVAETLAIERAKKLFGAQFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAAGGHLTHGAPVNMSGKWFKAAHYTVRRDDHLIDMDEVARRAEEVKPKLIIAGGSAYSRPWDFKRFREIADSVGAYLMVDMAHFAGLVAGGVHASPVPHAHVTTTTTHKSLRGPRGGLILCNDEALAKKFNSAIFPGLQGGPLMHVIAAKAVAFGEALRPDFKIYAKNVVENAKALAESLRGNGFDIISGGTDNHLMLVDLRPKGLRGNVSEKALVRAAITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFKQVGGLIAEVLNAIAQADDGKAPLVEAAVKEKVKALTNRFPIYQD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_BUCCC
Sequence: MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVVILGQDPYHSAGQAHGLSFSVPKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGVFLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGVVFLLWGNISQKKYYLIDSKKHFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHC_ECO81
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLDVKGFQQWVAEVLALAL
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: FABZ_SHESW
Sequence: MSNQMNTMDITEILKYLPHRYPFLLIDRVLDYTPGESLHAIKNVSINEPFFQGHFPIQPVMPGVLILEAMAQATGLLAFKTMSNDVPPPGVLYYFAGIDNARFRRVVVPGDQIHFEVKMIKERRGIGVFYGEARVDGEVACSAEIMCARREINQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAU1A_EXADI
Sequence: MKTAMLIAVLGFCAALCFVESSHEEEREAAVYLTDLVSKAESAIKRGIPCRCDKNSDELNGEQSYMNGNCGDGWKKCRSVNAIFNCCQRV
What is the function of this protein?
Cardioactive peptide that acts on voltage-gated sodium channels (hNav1. 5/SCN5A) and voltage-gated potassium channels (Kv) (PubMed:23356888, PubMed:24749540).  The activity on sodium channels consists of inhibition on sodium current inactivation with no significant effect on current activation.  This effect may be caused by direct interaction of the toxin with sodium channel site-3 (PubMed:23356888, PubMed:24749540).  The activity on potassium channels consists of a significant increase of the amplitude of the transient component of the potassium current, shifting the current threshold to more negative membrane potentials.  These effects are concentration-dependent and reversible and may be due to a direct interaction between the toxin and the voltage-sensing domain of the channel (PubMed:24749540).  Physiologically, this toxin increases the amplitude of cardiomyocyte contraction and slows the late phase of the twitch relaxation velocity with no induction of spontaneous twitching.  It increases action potential duration of cardiomyocytes with no effect on its threshold and on the cell resting potential.  On insects, it shows neurotoxic activity to the blowfly larvae S. falculaty, causing an immediate spasm that progressed to body contraction and paralysis.
What are the official names of this protein?
Delta-aiptatoxin-Adi1a, Delta-ATTX-Adi1a, Ion channel modifier Ade-1, Ade1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: TIG_SHEON
Sequence: MQVSVEATQGLERRLTISVPAEQIEKLVKDSLQREAKRARIPGFRPGKVPVTVINKRYGAAIRQDITGEVMQRNFIEAIIAEKLNPAGAPTFVPGATDGEKFEFVATFEIYPEVELKGLDAIVVEQPKASVTDADVDSMIETLRKQHATFAAVEREAVDGDKVKMNFVGSVDGVEFEGGKAEDFELQLGSGRMIPGFEAGILGHKAGEEFVIDVTFPEEYHAENLKGKAAKFAITLTEVLAANLPEVNDEFAALFGITEGGLEALKTEIRKNMNRELEQALKANVKEQVIAGLLANNDIELPKALIDGEVNVLRQQAMQRFGGQTANMPELPAELFTEQAARRVKIGLLLGEVIKTNELKAEDERVQGLIASMASAYEDPSEVIAYYNSNKELMQNMRNVALEEQAVEALLKTAKVTEKTVAFEEFMNKATGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NDPA_PSESM
Sequence: MPIRHCIVHLIEKKPDGTPAVLHARDSELAESQAIENMLADLNESYNAKQGKAWGLFHPESGAHPFSGWLKEYLDGGKDFTAFSRVSVEHLQKLMEESNLSVGGHVLFAHYQQGMTDYLAIALLHHSDGVAVNAELDVTPSRHLDLGQLHLAARINISEWQNNKQSKQYISFIKGKNGKKVSEYFRDFIGCQEGVDGPGETRTLLKAFSDFVESEDLPEESAREKTKTLIDYASSQSKMGEPMGLEALSELIDENQPRAFYDHIRNKDYGLSPEIPADKRTLNQFRRFTGRAEGLSISFEAHLLGDKIEYDETAGTLIIKGLPTQLTDQLKRR
What are the official names of this protein?
Nucleoid-associated protein PSPTO_1265.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HPA3_YEAST
Sequence: MSNEEPEKMVNDRIVVKAIEPKDEEAWNKLWKEYQGFQKTVMPPEVATTTFARFIDPTVKLWGALAFDTETGDAIGFAHYLNHLTSWHVEEVVYMNDLYVTERARVKGVGRKLIEFVYSRADELGTPAVYWVTDHYNHRAQLLYTKVAYKTDKVLYKRNGY
What is the function of this protein?
N-acetyltransferase that acetylates histone H4 at 'Lys-8'.  Also acetylates polyamines like putrescine, spermidine and spermine (PubMed:23775086).  Acts on a wide range of D-amino acids.  Catalyzes the N-acetylation through an ordered bi-bi mechanism, in which acetyl-CoA is the first substrate to be bound and CoA is the last product to be liberated (PubMed:15375647).  D-amino acids are toxic for the cell and their N-acetylation, preceding removal from cells, plays an important role in detoxification of D-amino acids (PubMed:10600387, PubMed:16362288).
What are the official names of this protein?
D-amino-acid N-acetyltransferase HPA3, DNT, Histone and other protein acetyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYR_XANCP
Sequence: MKAQLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLAKAARSNPRALAQALLAALPASDDVARVEIAGPGFINFHLTPAAYQREVIHVIKQGHDYGRGLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVLDANGWNVKREFYYNDAGVQIENLALSVQARAQGLTPDSAGWPENGYRGDYIADVAKAYLAGDTVDLEGHLVTGTKDPADLESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVDEAVQKLIASGHTYEEGGALWLKSTDFGDDKDRVMRKSDGTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVRAGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGSYVTLRDLIEETSADAVRWFLIARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGLKYDQTHGMAELARLDDEHSLALMLELSRYAEVVELAGQTLEPYQIAQYLRELAHAFHTWYHNSKVLVDDAAERDAKLTLAVATQQVLANGLELLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_CROS5
Sequence: MMFNFAQPVYPLVLTAAKNNPENAHQQLLKTLHRLDENRHTVWGKWILENLDHSFTFEDSRLQQNLWGLTFKTPVGLAAGCDKDGLAAGIWDHFGFGFAEIGAVTLHAQPGNPKPRLFRLPQDKAALNRLGANNQGAQKVAQTLKETWQRQPRQIPIGINLCKSKITPLEQAAMDYVGSFRYLEEDADYFVVNVSSPNTPGLRSLQEGEQLNVILQELQSVNSLTKPILVKISPDLSWESIKLIIKLAKTYQLAGIIATNTTIKREGLKTNILEKTGNSIQEEAGGISGQPIRQRSTEVIRFIYEQTQGTLPIIGVGGIFTAEDAWEKITSGASLLQLYTGWIYQGPWCISNINRGLVRKLEKYKLSHISEAVGMDFNS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: POLIB_ORYSJ
Sequence: MAVAPPLPPAPARLLRRWQGSSPWLSSSFGRTRYFSRPAFAAGGRQDYSPSSGMGVSKTGAFRLGLHGNLNVQSSVQEWVDETKRLFFLRTTNNVRNNITNGTTPLRVGNLRHDPSEDIRSSNYPSLYNQRERGPSNSIVNRHVDTDLAKHRVMYQSAHAVPAPFSVANNDIKPLNLLDGSKEEIPWHDSVTVESSLPKVSKSETTLVVDKAIPNKKEHKRITRKVTLNIPDKASLSTESKNARKLLATIYDKVLVVDNVESARSVVKLLTTKYKGFIHACDTEVANIDVKEETPVGHGEVICFSIYSGNSDGEADFGNGKTCIWVDVLDGGRDVLMEFAPFFEDPSIKKVWHNYSFDSHVIENCGIKVAGFHADTMHLARLWDSSRRADGGYSLEGLTNDHRIMNAVLKDIHKTGKVSMKTIFGRKNVRKNGSEGKTISIEPVKKLQREDRELWICYSSLDSMSTLKLYESLKNKLEAKEWIFDGCPRGTMYDFYEEYWRPFGALLVKMETEGMFVDRAYLSEIEKTAVVERKLAADKFRKWASKHCPDAKYMNVNSDNQIRQLFFGGIKNRNKPGETWPQSKAFKVPNDESIATEGKKIPKSRTIKLFTIVEDLKLFTTEGKKTTKTGWLKVRGDVLWSLAGKIPTDHIYKIDDDGQEFDEDGSSVELPEQDIEDTSPYGTAYEAFGGGKKGREACHAIAALCEVFSIDKLISGFIVPLQGDHISCKEGRIHCSLNINTETGRLSARTPSLQNQPALEKDRYKIRQAFVAAPGNTLIVADYGQLELRILAHLTNCKSMLEAFKAGGDFHSRTAMNMYQHVRDAVEEKKVLLEWHPQPGQDKPPVPLLKDAFGAERRKAKMLNFSIAYGKTAVGLSQDWNVEVREARDTLKLWHRDRKEISAWQKKQKALAFEKCEVYTLLGRSRQFPNMTHAGPGQKSHVERAAINAPVQGSAADVAMCAMLEIERNARLKELGWRLLLQVHDEVILEGPTESAEEAKAIVVECMSKPFYGTNILKVDLAVDAKYAKSWYAAK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.  May be required for DNA replication and accumulation in mitochondria (By similarity).
What are the official names of this protein?
DNA polymerase I B, mitochondrial, DNA polymerase PolI-like B, OsPolI-like B, DNA polymerase gamma 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y305_METJA
Sequence: MPMNIVNMFGKYIKIIKWIGIASLIGIVGGLSSVIIAIIIEYFPEKHNVLLIPIVFFIAGLFVDYIYELKGSGIDRVLKALNTNEKLTWIRGLLKVLLAGAVIAVGGSAGKEGPCVQSSASFADELYRLLKLKNRELVIITGIAGGLGGAFSAPLGTAILACEIIEHENFNYINLIPPIIASVVGYLIFYLITGRKHLFNITLSYTINIHDFLLFILGAFFCSLIAHCYIKTYRKISSTFDNLKIPYCIKTLIGGILVAVISYFIPEVMGMGLTLTKELFIMEFSLVFLVLLLIGKILATSFTVGSGTPGGLVFPSMCIGAISGIIFGSLIGDCSAPYIVLGIATTLSATTNAPLGGAVLCTEIFGFDFAVPASIGAVIGYQMTKLETIFKYIRF
What are the official names of this protein?
Uncharacterized protein MJ0305.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CATE_MOUSE
Sequence: MKPLLVLLLLLLLDLAQAQGALHRVPLRRHQSLRKKLRAQGQLSEFWRSHNLDMTRLSESCNVYSSVNEPLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSDTYTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAAGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTKQAYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPDKIKQLQEAIGATPIDGEYAVDCATLDTMPNVTFLINEVSYTLNPTDYILPDLVEGMQFCGSGFQGLDIPPPAGPLWILGDVFIRQFYSVFDRGNNQVGLAPAVP
What is the function of this protein?
May have a role in immune function.  Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.  May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
What are the official names of this protein?
Cathepsin E.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.