PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_NDVB1
Sequence: MSSVFDEYEQLLAAQTRPNGAHGGGEKGSTLKVDVPVFTLNSDDPEDRWSFVVFCLRIAVSEDANKPLRQGALISLLCSHSQVMRNHVALAGKQNEATLAVLEIDGFANGTPQFNNRSGVSEERAQRFAMIAGSLPRACSNGTPFVTAGAEDDAPEDITDTLERILSIQAQVWVTVAKAMTAYETADESETRRINKYMQQGRVQKKYILYPVCRSTIQLTIRQSLAVRIFLVSELKRGRNTAGGTSTYYNLVGDVDSYIRNTGLTAFFLTLKYGINTKTSALALSSLSGDIQKMKQLMRLYRMKGDNAPYMTLLGDSDQMSFAPAEYAQLYSFAMGMASVLDKGTGKYQFAKDFMSTSFWRLGVEYAQAQGSSINEDMAAELKLTPAARRGLAAAAQRVSEVTSSIDMPTQQVGVLTGLSEGGSQALQGGSNRSQGQPEAGDGETQFLDLMRAVANSMREAPNSAQGTPQSGPPPTPGPSQDNDTDWGY
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MAVI_CUCPE
Sequence: ATVHKVGDSTGWTTLVPYDYAKWASSNKFHVGDSLLFNYNNKFHNVLQVDQEQFKSCNSSSPAASYTSGADSIPLKRPGTFYFLCGIPGHCQLGQKVEIKVDPGSSSA
What are the official names of this protein?
Mavicyanin.
Protein: PUS2_YEAST
Sequence: MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVHAMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKFNARSACDSRWYQYLIPEFILIGPPRSSLLHRNVGGCYREDGSQEVWDTFLEQTRGRFSGDELCRLQDTAQKLSESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHNFTTGKLWGDPSAQRHIKKVVVSQASPGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLLYCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNRLATPLI
What is the function of this protein?
Mitochondrial-specific pseudouridine synthase catalyzing the formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of mitochondrial transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine(27/28) synthase, tRNA pseudouridine synthase 2, tRNA pseudouridylate synthase 2, tRNA-uridine isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UB2D2_MOUSE
Sequence: MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.  Mediates the selective degradation of short-lived and abnormal proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6.  Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection.  Essential for viral activation of IRF3.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D2, (E3-independent) E2 ubiquitin-conjugating enzyme D2, E2 ubiquitin-conjugating enzyme D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL20_BORHD
Sequence: MARVKNGIVHVARRKRLLKKTKGFWGTKKSNYKKAKDTLRKGMMYATRDRKARKRDFRSLWIVRISAALTGMGITYSRFFEGLKKSNIKLNRKILSNLAIEDIETFKKIVYEIKN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RISB_SALNS
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HIR1_CRYNB
Sequence: MKVTKPNWVEHTVGEKKAKTAIYSISVHPDGTRLATGGLDHKVKIWSTLPILDVEAEKEEENPKLLCTMSSHTGSVLSVRWAHHGRFLATGSDDQVIMIWGLDPDGGGRLWGSDEINVENWKALTRLVGHVADVVDLAWSRDDTMLASVGLDSTVWIWDGLTFERLRKLDLHQGFVKGVCWDPVGNYLATQSDDKTVKIWNTEDWSLAETISKPFETSPQSTFFRRLSWSPDGAFIAASNAMNGPVFVAAVIDREGWASDISFVGHENTIQVAAFNPRLFFPEGEPKGRATASSMLALGANDFSISIWRNTLYKPLVVLKDIFGADLMDLCWSNDGYVLYGSSVDGSVCAIQFEPSEFTDLADFSATELVLREYDYKPKRAHQPLAVHSSAASITNGFGPSTTTSTHVNVLQPKKGKAKRRVDLSNGNINAGPSAGPSRQALRPPPPVDPFSGPIQGFASPSTAQASTARMFEDAHRAFGPGSGSISGTSPRAGDKRKASGSYEDPTRGVRGRGMPVQQPIQQFEVQIIRAPMVAPSPSDAGPSKAYLPYPQVQSILRAQAIGNESRSIYLEARNTSDPKGENVLCYFADGEQRWMDYLPKAALAVTVTKNFCAAACEDGSLRVYSPAGRLILNMKLSGLVYDLQGEDKMLLIITMDCQVRVINVRNGKAFSPPSSIHHLLFPGSSSFHSFDIISCTVRPNGVPVIITSEPQAFAYDASLHEWSTIASPPIAGIQPLPSGPSGPLSVVDQIVAKSAPVTTTEKSNAPWIEESYVMSQFEMKLRGTVLLDSKEEHKHWLLGYMKYLGDENFAERAGEVMKDLIGPVYHQSKPTGWEPKLLGVDKREIAAEVLDVLSKTLQGKNVASVWYDVLDKMKADEGSW
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYC_PANTR
Sequence: MDFFRIVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCPSQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: PAND_NOSS1
Sequence: MQRTLLLAKIHNCTLTGANINYVGSISIDQILLDKSGILPYEQVQVVNNANGQRFITYAIPAPAHSGIIELNGAAARLGIIGDRVIIMTYGQFTSEELKSYTPTVVIVDEKNRPLEVRRYDDLLSQV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_RSVT
Sequence: MGTNKPATLADLQKAINDISKDALSYLTAHKADVVTFAGQIEYAGYDAATLIGILKDKGGDTLAKDMTMCITMRYVRGTGFVRDVTKKVKVAAGSTEASTLVSRYGIVSSVGTNANAITLGRLAQLFPNVSHEVVRQISGVKMAVDSSDLGLTGCDNLLWDYVPQYIKLESETAPYCSTHSLSHILFVVHIIHSFQITKKTMPEGKKKERGLTKDIDMMKYTTGLLVITCKSKNLSDKKKEEGRKKVLDEFITNGKVKTTIFDALAGMSVNTISTYGNQTRLYLAQQSKLMKILAENTSKTATEVSGLVKEFFEDEAEGADD
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC), and serves as template for viral transcription and replication.
What are the official names of this protein?
Nucleoprotein, Coat protein, CP, Nucleocapsid protein, Protein N, Protein pc3.
What is the protein family that this protein belongs to?
Belongs to the tenuiviruses nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TRM56_SACS2
Sequence: MTTHVILVARAFGAKGVYIEGKDEKMVKSILKVIDSWGGSSYFLVKEIENGKSIVNEWKEKGGTIIHLTMYGININDFQDRFEKIKYPLLIIVGAEKVEGWYYHNADYNIAIGNQPHSEVAALAIFLDRIYKGRELYMEFEDAKIKILPQKAGKKVIRSG
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SYNS3
Sequence: MIKLRLKRFGKKREASFRLVACNSTSRRDGRPLQELGFYNPRTKETRLDAEALRVRLSQGAQPTDAVRFLLEKGGLLEKTVRPAETIGKLKQAAAREAAVKQAAKDAAEAKAAAANESDDSGTDSTES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HISX_BACSU
Sequence: MKIKTISGAERLSLKRSIDAGTEEQRKTVRSIIEDVKANGDQAVRSYTAKFDCIEIDSPLVTKEEFEEAYTSLDSRLLQVIRQAIENIREYHERQLQSSWFYHRKDGTMLGQKVTALDSAGVYVPGGTAAYPSSVLMNVIPALVAGVERIVLVTPPGKDGLLSPGVLVAAAELGIKDIYKMGGAQAIAALAYGTETIEPVDKITGPGNIYVALAKREVFGDVDIDMIAGPSEIVVLADETAIPSEIAADLLSQAEHDKLSSCVFVTDSMALAETVSAEVNKQLETLPRREIAEASVRDYGCIYVAETMVEAIETVNTLAPEHLEIITQSPEALLGSIKHAGAIFLGRYSPEPVGDYFAGPNHVLPTNGTARFSSPLNVTDFQKKSSIISYSQSAFEEHAESIAAFARLEGLEAHARSIEARERRISK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: CHED_XANOM
Sequence: MSTAVQVDDVMRYRDSRFQTIAAKLLPTQYLVVDDDTALTTTLGSCVAACLRDPVLKIGGMNHFLLPEGQIGDGAPARYGSYAMELLINDMLKRGAHRKRIEAKVFGGANVLKGFTSNPVGTRNAEFVRQYLQAEHIPIIAEDLCGIHPRKVWFFATTGRVAVQRLPHAHEAEVAATESAVRARLSKAPVTGGVELFE
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: VKTP1_CYRHA
Sequence: MGIARILSAVLFLSVLFVVTFPTLLSADHHDGRIDTCRLPSDRGRCKASFERWYFNGTTCTKFVYGGYGGNDNRFPTEKACMKRCVKA
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1p, U15-TRTX-Hhn1p, Kunitz-type serine protease inhibitor hainantoxin-XI-16, HNTX-XI-16.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 01 (intermediate) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_BACTN
Sequence: MRKAKPKKRVILPDPVFNDQKVSKFVNHLMYDGKKNASYEIFYAALETVKAKLPNEEKSALEIWKKALDNVTPQVEVKSRRVGGATFQVPTEIRPDRKESVSMKNLILFARKRGGKSMADKLAAEIMDAFNEQGGAYKRKEDMHRMAEANRAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: 072L_IIV3
Sequence: MEDEDDIFENQPEFLAERNVWARVGGPDIGLGLGGMINLKKSGYTIGEKFKLIAAATIKMLNDGMEEDLLSDAALTRMLSLVESDKMPDFQTKNPSAFAMGYVVAIHSNYNTLEIDREKLEVIFKLNNELESSFFSRIEERDILRYVRFCLIHKLK
What are the official names of this protein?
Uncharacterized protein 072L.
Protein: CD8A_BOVIN
Sequence: MASLLTALILPLALLLLDAAKVLGSLSFRMSPTQKETRLGEKVELQCELLQSGMATGCSWLRHIPGDDPRPTFLMYLSAQRVKLAEGLDPRHISGAKVSGTKFQLTLSSFLQEDQGYYFCSVVSNSILYFSNFVPVFLPAKPATTPAMRPSSAAPTSAPQTRSVSPRSEVCRTSAGSAVDTSRLDFACNIYIWAPLVGTCGVLLLSLVITGICYRRNRRRVCKCPRPVVRQGGKPNLSEKYV
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex.  The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs).  This mechanism enables CTLs to recognize and eliminate infected cells and tumor cells.  In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells.  CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD8 alpha chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=CD8A localizes to lipid rafts only when associated with its partner CD8B.
Protein: AKND1_MACFA
Sequence: MDEADFSEDTTYKQEDLPYDGDLSPIKICNDYSFTSKNDAFEVSSQIIFIADDPQEKAMHNETCGNTAMTMPLGKTTENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKEPFLRGQGIDCETLPEISNADSFEEEAIIKSIISCCNKNSWPKEQTLELTDQLNPKKDGENSNKPGSPTMTEENTSDLEETVAAGDSSHQENVNILTKTKGPGDKQNSYQGQAPPKQHTEKASSGNRFKYGQGQVHYQLPDFSKIAPEVKNPKNNIINKPLAIAKQVSFSKLREKPAVVQDILETMPESNCVEKQHQEQKGEITEPSQQIQMEPTVHIHQELLTGIESEASISKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVREFSKRIKQESPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVSDFDPERKVEGEIFKLEMLLEDVKDKVDESKYTSAPSLPVSSPVTLDDLASTSSSLSNEVPEEHPGHPPGPRGSGGSEATGTPQGGPQEAPKEELCELTPQIYLNGHYGDATVQNQPDQVAMRLSSNSGEDPRCTPGRQDCAETTAPSPSCAFCRRLLEWKPKVEKKGHRRIHCGRFSTVHEKAPHSDSTPNSDTGHSFCSDSGTEMQGNKCQDCGTKIPTSRRACRKEPPKEFHYRHNTPGENYSNHSKRGAFVRPHSLHESKNSSPSLASPFCCPGLMYSPDTSKSSPTPGWQEAELGLENMKSQ
What are the official names of this protein?
Protein AKNAD1.
What is the protein family that this protein belongs to?
Belongs to the AKNA family.
Protein: RF2_SULSY
Sequence: MIVEEIKTKWEEIKEKWDNLKEILKPEKLEEEIKQLDDLMADPNFWNDTKKAQEISSRRNYLGEKLEEILTVDKKVNNLLDYITLLEMEEDQELYNEVEKELKEIEKEISRLELGSLLSDEMDSKNAILTVQAGSGGVEACDWTEMLLRMYTRWAEKRGYQVELVDFQPDDVAGVKSATLIIKGPYAYGYLKGEQGVHRLVRISPFDANKRRHTSFSAVSVIPEIDEDIKVEINEEDLRIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVACQSERSQLQNKLKATNMLKAKLYQLELEKRKEKQKELEGEKKDITWGSQIRSYVFQPYQMVKDLRTGFETGNIEAVMDGEIDDFIESYLKWKAKGGQ
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1078_LATSS
Sequence: MMIKQETIGYMTLKSDAAKIEALLTKQFDALCLSQCPIIEEIIDTQLFGFTKEVDFAKRVRLISDQEGSQLVNELETRINQLYLEIYQTQAQNEVHRN
What are the official names of this protein?
UPF0358 protein LCA_1078.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: MATK_CHAFS
Sequence: MEEFQVYLELARSRQYDFLYPLIFREYIYALAYDHGFNNSILVENLGYDNKSSLLIIKRLITRMYQQNHLIISANDSNKNPFWGCKKNLYSQLISEGFAVSVEIPFSLQLISSLEGAEIVKSYNLRSIHSIFPFFEEKFAYLTYVSDVQIPYPIHLEILVQTXXXXXXXXSCFHLLRLFLYEYWNWNSLITPKKWISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSYLRLTSSGVLFERINFYAKIEYFVEVFDKDFLSTLWFFKDSFIHYGRYQGKSILASKNTPFLMTKWKYYLIHLWQCHFYVWSQPGKIHINQLSEHSFDFLGYFSNVRLNPSVVRSQMLENSFLIENVMKKLDTIIPIIPLIRSLAKAKFCNVLGHPISKPVWADSADFDIIDLFLRRCRNLSHYYNGSSTKKSLYRIKHILRLSCIKTLARKHKSTVRVFLKSLGSELLEEFFTEEKEILSLIFPRASSTLQRLYRGRIWYLDIFYFHQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RCOR2_RAT
Sequence: MPSVMEKPSAGSGILSRSRAKTAPNGGQPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGAVSEGEPDTGDPKREPLPSRPLNARPGPGKKEIQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPTAPVPVEEARRGAPVPATALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAASRHSARPGPQPPPTLVGAQLEPPAPSL
What is the function of this protein?
May act as a component of a corepressor complex that represses transcription.
What are the official names of this protein?
REST corepressor 2.
What is the protein family that this protein belongs to?
Belongs to the CoREST family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAS1_NEUCR
Sequence: MANKFTREYKLVVVGGGGVGKSCLTIQLIQGHFLDEYDPTIEDSYRKQCTIDNEVALLDILDTAGQEEYSAMREQYMRTGEGFLLVFAINSRESFEEIRIYQQQILRVKDRDSFPMIIVGNKYDLRGERVVSEQEGQALAAEFGTKYIETSAKTQHNVENAFYDLVREIRKEDKKLGEKVGGTSFANNNGAVKQMDVGDEDVQAGCCAKCIMM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Protein ras-1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ACTPB_ACTTE
Sequence: MNRLIIVFIVVTMICAATALSTKRRINKEEKDEKRSVAVAGAVIEGATLTFNVLQTVLKALGDISRKIAVGIDNESGMTWTAMNTYFRSGTSDIVLPYEVPHGKALLYNGQKDRGPVATGVVGVLAYAMSDGNTLAVLFSIPFDYNLYSNWWNVKVYKGHRRADQRMYEELYYNLSPFRGDNGWHNRDLGYGLTSRGFMNSSGQSILEIHVTKA
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
Cytolysin tenebrosin-B, DELTA-actitoxin.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: SSRP_STAAB
Sequence: MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIIKLGDQTREIGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YIPF5_XENLA
Sequence: MSNFDNFNTDFYQTSYSIDDQSQGYNYNAGGAQYSKQYPYDPYSQQGGFILQEMNQQQQPYTGQIYQPTQTYTPTATESVYGSTFDDEPPLLEELGINFDHIWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISAMGCLGMYCLLNLMSMTGVSFGCVSSVLGYCLLPMIILSTFAVIFSLQGILGIVLAALIIGWCSFSASKIFISALAMDGQQLLVAYPCALLYGVFALISVF
What is the function of this protein?
Plays a role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Protein YIPF5, YIP1 family member 5.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.