PharMolix/UniProtQA huggingface dataset:
Protein: TRF41_DROME
Sequence: MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSSSNSGNNNNNNNNNIINNTITNTTNNTGNNSSAKPYLSRPYSSLNRVLNFRADSLEILQQQQQQQQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGPGAGTGTSTGAGGTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAGGAHYYMNNHMEMIAKYKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAVTTTTTMAVVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVVETTSSAQEVVDIALSTPNGLANMSMPMPVHAVGMPASNSWSGNGNGNGNSSSSTGSSPEIAHIAAQEMDPELEDQQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGRNYNQRNNHNSSGYYHQQYYVPPPMQQQLSKSNSSSNYHQQHHHSHSHGNHSHRQQHHHQQQHHHQQRPQHLRVGGGNRYQKSLGGSPIISAGNASNSSSNCSNSSSSSGSNNSRLPPLRGTLVNSSSAISIISISSESSIASSSSSSSRSGQDQQRDER
What is the function of this protein?
Involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information (PubMed:18765642, PubMed:26786835).  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates (PubMed:26786835).  Polyadenylates RNA processing and degradation intermediates of snRNAs and mRNAs (PubMed:18765642, PubMed:26786835).
What are the official names of this protein?
Non-canonical poly(A) RNA polymerase protein Trf4-1, Topoisomerase 1-related protein 4-1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched in 3 to 6 cytoplasmic foci.
Protein: HTPG_NITHX
Sequence: MTSTIDSDGAAESRVFEADVAKLLQMMVHSVYSDKDVFLRELISNAADACERLRYDAISDPALLADDARPQIAITIDAERRQLTVDDNGIGMSRDEMVDALGTIARSGTKAFIEQAKVEQAKSAEAGDGVTVIGQFGVGFYSAFMVADQVDVISRRAGAGEAWRWSSDGKGTFTVTPADESEAPARGTRVMLHLTEDAKGYTDRLKLEQIVREQSGHVPVPIVLVEQPGAAPTEIADGAALWTKPRGEIGTSEYVDFYRSVAGHFDEPALTVHFRAEGRQEFTALLFVPQTRSFDLFETDRKGPIKLYVKRVFITDDADLLPRYLRFVRGVVDSADLPLNISREMIQESPILAAIKKSITGRVLSELEKLAEKDAQAYGKVWEAFGPMFKEGIYDAADRRDAILSLCRFRTTAGSLRSLKDYVGALKDNQTSIYYLAGQDAARLEASPHLEGFRARGVEVLLLSDPVDSFWVTSAPSFEGKPFKSVTQGDTDLAAIPRVDASAETLQEVSASVTEFLAFLKTTLADLVSDVRSSERLTDSPVCLIAAESGPDRQLEKILVGVGQLTGASKPVLEVNPRHPLIASLAALGDGDRAFKEDTARMLLDDARVLDGDRPSDALEFSRRLARIVERGLRGSTA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AOP2L_ARATH
Sequence: MGSCSLQLPLINLADKTLEPGSSKWAEVRSDVRKALQDFGCFEASYDKVSLELQESIMKTMEELFALPVETKQRNVCPKPYVGYLNHNNLSESLGISNANILENINEFTQQLWPHGDGNENISKTIQLFAEKLVEIDVMVRRMVMESFGIEKYIDDHLKSTEYRMRLMKYIAPPEGDANTTVDDYADLLAKLNIDGVEPNVGVKVNADISDDVNANPSVNAGVGANVNADTGVNDNLNVDAEANGDANIAVGGGVNANTDLGVGVNVNSNVAVNAKTGATSGDDVEANDDNEEKKLGLPCHTDKNLFTVLFQHEIEGLEVKTKDEKWIRVKPSPNTFIVIAGDSLCALMNGRIRAPYHRVRVTEKKRTRYTAAIFTCPKPDYVIEAPKELVDEKHPRLFRPFDYRDLFTFYHSEAGRKIQYTLQAYCAVSEA
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis.  Catalyzes the conversion of methylsulfinylalkyl glucosinolates to alkenyl glucosinolates.
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase AOP2.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PUR5_STAA8
Sequence: MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CHLCV
Sequence: MTMTLLSYLSSLCREATLSAFPQIDTFSPDITQSTKEHFGHYQCNDAMKLARTLKMAPRAIAEAIVNHIPKEIFTSIEIAGAGFINFTFSKEFLNNSLKTFSEELSSGFRVKDPKKVVIDFSSPNIAKDMHVGHLRSTIIGDCLARVFAFVGNDVSRLNHIGDWGTAFGMLITYLQEEPSEDIENLEDLTVLYKKAHARFAEDAEFKKRSQTNVVALQAGDPSALKLWKQICAISERAFQKIYNILDIAIEKRGESFYNPFLPEIIQDLENKNLITISDNAKCVFHEGFSIPLMVQKSDGGYNYATTDLAAMRYRVNNDGADKIIIVTDMGQSLHFQLLEATALAAGYLPNKETFSHVGFGLVLDSEGKKFKTRSGENIKLKELLDTAIDQAKATLKEHRPEISDEEISSRAPILGINAIKYADLSSHRVSDYIFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGIETLDLEATPNIQEPSEEALALALLRFPEAIDLTLKDLCPHFLTDYLYMLTNKFNAFFRDCHIEGSSHQKERLYLCALVEKTLAAGMHLLGLQTLDKL
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE8E2_BPV1
Sequence: MKLTVFLRPSRDRPDGVWVASEGPEGDPAGKEAEPAQPVSSLLGSPACGPIRAGLGWVRDGPRSHPYNFPAGSGGSILRSSSTPVQGTVPVDLASRQEEEEQSPDSTEEEPVTLPRRTTNDGFHLLKAGGSCFALISGTANQVKCYRFRVKKNHRHRYENCTTTWFTVADNGAERQGQAQILITFGSPSQRQDFLKHVPLPPGMNISGFTASLDF
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GATC_METS4
Sequence: MSVDAQTVRRIAHLARIAVSDAEVPPLQDELNAILAFVEQLGAVDVSGVEPMTSVTPMAMKQRDDAVTDGGYAREIVFNAPLSEDNYFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: YRF13_YEAST
Sequence: MEIENEQICTCIAQILHLLNSLIITFLDDDKTETGQSFVYIDGFLVKKHNNQHTIVNFETYKNKMKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRGLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGVSVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMIHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
What is the function of this protein?
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
What are the official names of this protein?
Y' element ATP-dependent helicase protein 1 copy 3.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: VGRG5_PSEAE
Sequence: MFAPANQTHFSLRIENLRHDFQVLAFRGREAISQPFRFDLELVSERSDLDLDALLHQPAFLILSPSGQGVHGQLTSIAQGDSGKRLTGYRATLEPRLAYLGLCSDQRIFQRLSVPEIIGRVLEGHGILADAYRFQLGPTPYPAREYCTQYDETDLAFLSRLCEEEGIHYHHEFSAQGHVLVFGDDQTSFPRLQRPVAYVQDAGLVADQPVVKRFGVRFDTRASRVTRRDYDFEQPALQMQAAHGPQPGAQQPDLEDYDYPGRFTHRERGKHLSHRALERHRADYLQARGESDEPALLSGHFLTLSAHPRGEWNDLWLLTEVLHEGRQPQVLEESIDSDVAQGQGDFRQGYRNHFVATPWSAHFRPPLEHPRPRVLGCQTAVVTGPAGETIHCDQYGRVKVQFFWDRLGQADDNTSCWLRVASNWGGKRYGGVAIPRVGMEVLVGFLEGDPDQPLVTGCLYHSENRVPYELPQNKTRSVFKTDSYPGGGGFNELRIEDRKGQEQIFVHAQRDWDENIEHDQKIRVGHERHDTVEGDSYSEFRAEEQRTVHADRKVELKAADHLSVADALHLRIGTGQFVEAGDEIHFKAGDKVVIEAGMELTLKGGGSFARLDPGGVTLDGAQVMINSGGSPGIGSGVRALSPLQPLAADAAAAGGALLGAIAQKIGEAPQKLLRFELSPLPGVASAARQPYRLYANGAFKEEGIADEGGAISFEPLPGERTYRIETANGHAYEVEMVDQPDALQADDRLAQQGFRDYRAEMPQHKPRSAPDAYRRDASRPGAADKDEPTP
What is the function of this protein?
Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection.  Allows the delivery of the phospholipase effector PldB to target cells where it exerts its toxicity.  Also plays a role in VgrG4b and its effector PldA secretion.
What are the official names of this protein?
Type VI secretion system spike protein VgrG5.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: AR1AA_XENLA
Sequence: MSLHQFLLEPISCHAWNKDLTQIAISPNNHEVHIYKKSGDQWVKGHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKTRVFSAYIKEVDEKPASTPWGSKMPFGQMMAEFGGVSSGGWVHSVSFSASGNKLAWVSHDSTVSVADASKNMSVSQLKTEFLPLLSVIFVSENSLIAAGHDCCPMLFTYDEHGSLTFVSKLDIPKQSTQRNISAMERFRNMDKRATTEDRNTTLETLHQNSITQVSIYDGDKTECRKFCTTGIDGAMTIWDFKTLESYIQGLKIM
What is the function of this protein?
Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (Probable).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 1A-A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ARPC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: RL1_IDILO
Sequence: MAKLTKRARMIAEKVEARDYDVNEAITLLKELATAKFTESVDVAVNLGIDARKSDQNVRGATVLPNGTGRDVRVAVFTSGDNAEKAKAAGADIVGMEDLAAQVKKGEMNFDVVVASPDAMRVVGQLGQILGPRGLMPNPKTGTVTPDVATAVKNAKAGQVRYRNDKNGIVHATIGRVDFDNDKLKENLEALLAALKKAKPSSAKGVFVKRISLSTTMGAGVSIDQATVAAV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y810_CHRVO
Sequence: MPPLLRGGFGITFAAMQVQRLEPYFGFARFIARRMSCLRVLQISGSLTFTTLLALVPLFTIALSVISAFPVFSDYSTRFKIMLLSTLVPEFAGKVITVYMRQFADNAEKLTAAGIVMLGVTALMLMSTIERTFNAIWGVRRGRPWLQQSMVYWTVLTLGPLVLGGSLLSWRWLFKATRLEKNLPLLASVLEAGGTIVLTALVLALLYRIVPNRFVPFRHAVWGALVTSVLLELTKMGFGFYIGQVASYQLVYGAFASIPIFLLWVYCLWLVVLAGAVFTSALSYWEGDAWRRRNEPHRRFQDALEVLLLLDAAHARGEALTPRQLRQQVKVGYDELGLVLDRLAQRGYVQKGHGDAWVLMRRAAAINLSDLFQIFVYRRDASAGDALDATLAELLGPLTEQLQAVTVADLARRVGRK
What are the official names of this protein?
UPF0761 membrane protein CV_0810.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_STAA3
Sequence: MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTTGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_CORJK
Sequence: MTQTIQTQTGKNSGAGRTYEVRTFGCQMNVHDSERLSGLLEDSGYVPASEGVTPDVVVFNTCAVRENADKRLYGTLGQMKAIKDEHPGMQIAVGGCMAQKDKQTVVDKAPWVDVVFGTHNLGSLPTLLERSAHNHKAEVEIFDALEEFPSVLPAKRESAYAGWVSVSVGCNNTCTFCIVPSLRGKEQDRRPGEILAEVKALVEQGVSEVTLLGQNVNAYGVNFADETLERDRTAFSKLLRACGEIEGLERLRFTSPHPAEFTDDVIDAMAETPAVCPQLHMPLQSGSDKVLKDMKRSYRSKKFLAILDKVRERIPHAAITTDIIVGFPGETEEDFQATLDVVEKARFSSAFTFQYSPRPGTPAAEMENQVPKAVVQDRYERLLALQERISEEENRKLIGTTQELLVQADGRKNDRTQRRSGRSRDGRLVHFTPEGDVRAGDVVEVVITDAAPHFLIADGGVASHRRTRAGDMTELGETPTTAPVGVGLGMPSIKKPEPTTAGGCSTGGCGCE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRC_CHICK
Sequence: MRTWIFFFLCLAGKALAAPQEALADETEVIEDLTTEGPVGANPVQVEVGEFEEPTEDVEEIVAENPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPAHSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKNIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDFDKYIALEEWASCFGIKEQDIDKDLVI
What is the function of this protein?
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines.  Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes.  There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity).
What are the official names of this protein?
SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine.
What is the protein family that this protein belongs to?
Belongs to the SPARC family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Protein: RBL_CICIN
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGIEPVPGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPRHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKSQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLATEGNEIIREAAKWSPELAAACEVWKEIKFEFQAMDTLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RM14_ACAPO
Sequence: MINVQTVLKVADNSGAVFVSCIRLLNSSSRVGAGVGDTITVVVKKNIIKKNIKKSKEVKKGQVCSAIILRTIKGVKRWGNFFLRSSSNSVALINKYYLPIGSRLLGPVFREIRTNL
What are the official names of this protein?
60S ribosomal protein L14, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DABA1_NITHX
Sequence: MVMVDALNLGRRLRVRSTAYVAGEPVPFFWPMRTFIHHNPLYGLEHMPFEQAVRRGAELFHARMFLPRSDYQRWQREGKVRQDTLAEEIARRAQALPAVPGIDWPRWLQALMQSAHDRDVVVPGVRAPDVHAALHGQPPSAQAVDVAVLLPALEQRLHGLTLPEAVDALWGTRLADELDELVIKSYLDFFDEDQSSWRMPGRERGLFAAWSEIARRNARMFLRGLHVRRTLGRVQDPESAVVHVMEEMGIDPDAWSAYFTRELTRLHGWTGFVRWRSSAKHYYWAQRYPAEVVDLLAVRLVVGLALLQESARHRRTPVRREQLDALLHERGAECLLRNALHSGEVLPDWAQRIDDTLSRGGSKRCEALLQRYWPLWQARQGQDQAAALRELAAAADATAALEVLSPEDIAGLIQGLQEFARQEGMVWTLAMEAQAIDQLLAQVQVPQDLAAGKRPFAQAWFCIDVRAEPIRRHLERVGDYQTFGIAGFFGVPVGFLGYGKGSESHFCPAVVTPKNLVLELPAELDPEEDDLLSTLGHVLHDLKSSVLSPYVTVEAVGMLFGLDLFGKTLAPLGYSRWRNRIDADKPVTRLLVDKLTREQADSIIRTLQRAMIVKALHAELHIERERVDDDMIRELRETALRHREGPTRLQRTFGVSDKQEAEFIDKLREVYRVDADYASYQLVRLGRIGYSLDEQVNYVHTALTMIGLTKTFSRFVLIVGHSGQTENNPYESALDCGACGGASGLVNARVLAQMANKTAVRERLRGMGIDIPDDTWFLPALHNTTTDAIELSDLVLLPPRHLVYLDRLRNGLRAASRLAAAERMPKLLPQARAIEPAQAWRLAHRLAVDWAQVRPEWGLSKNVYGIIGRRSLSERADLQGRPFLMSYDWRCDPKGRLLENLLAAAVVVGQWINLEHFFSTVDNARLGSGSKAYHNVAGRFGVMTGSLSDLRTGLPAQTVMREGQPYHEPMRMIALIEAPLDFAGRALQSVVKVKSLVLGGWIRAIVIDPTQGYKPFVFNNGQWEERPPLVAPAEEEHAA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYSG_ECOL6
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEYGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: GLMM_VEREI
Sequence: MTRQHFGTDGIRGTVGQPPITPDFVLRLAHAVGRVLRQTQERPVVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLPTPGVAYLTCAQRASLGVVISASHNPYPDNGIKFFSAQGSKLSDAWEQAVETALGEPPAWTNSANLGKARRLNDAAERYIEFCKNTFAQDLSLKGLKIVLDAAHGAAYQVGPKVLRELEAEVIAIGCSPDGLNINHEVGATHPDTLVRAVHAHHADYGIALDGDADRVLIVDATGRLYNGDELLYLMVADRMGRDEHVPGVVGTLMTNRAVELALQARGVEFVRAKVGDRYILEELTRRDWALGGEGSGHLLALDRHTTGDGIGSALQVLQACVRSRSTLAQLLAAVTLYPQVLLNVRLPPDQDWTTNRLLADAIQAVEQQLGASGRVLIRASGTEPLLRVMVEARDAQLADSCAQRLANAARAGWQGHTSLKNAPPMGAN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL1_PETMO
Sequence: MPKHGKKYKEVLKLVDKQKNYDIDEALDLVKKTSYTKFDGTVELHVLLGIDPKKGDQNVRGTVSLPKGTGKNVRVLVFAEGEKAAQAKQAGADFVGSDDLIEKINNEGWTDFDVAIATPDIMRKIGRLGKVLGPRGLMPSPKAGTVTDDVAQAVKEFKAGKVEVRNDRTGNIHIPIGKVSFDKDDLKENLISAFDQLTKMKPENSKGKFIRKAVIASTMGPGINIDLSSLSLSSVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PLDA1_TOBAC
Sequence: MAQILLHGTLHVTIYEVDNLQKEGGGHFFSKIKEHVEETIGFGKGTPAIYATVDLEKARVGRTRKIKNEPNNPRWYESFHIYCAHMASNVIFTVKDDNPIGATLIGRAYVPVEELLEGEEIDKWVEILDREMNPIAEGSKIHVKLQFFDVSRDPNWERGIRSSKYPGVPYTFFAQRTGCRVSLYQDAHVPDNFIPKIPLSGGKYYEPHRCWEDIFDAIINAKHLIYITGWSVYTEITLVRDSRRQKPGGDITLGELLKKKASEGVKVLMLVWDDRTSVGLLKKDGLMATHDQETEQFFQGTEVNCVLCPRNPDDGGSIVQSLQIGTMFTHHQKIVVVDSELPSGESEKRRILSFVGGIDLCDGRYDTPFHSLFRTLDTAHHDDFHQPNFPDGAITKGGPREPWHDIHSRLEGPIAWDVLFNFEQRWRKQGGKDVLVNFRELDDIIIPPSPVMHLDDSETWNVQLFRSIDEGAAFGFPETPEDAAKAGLVSGXDNIIDRSIQDAYIHAIRRAKNFIYIENQYFLGSSYDWQSDDIKVEDIGALHVIPKELALKIVSKIEAGERFTVYVVVPMWPEGIPESASVQAILDWQRRTMEMMYKHIVQALNAKGIEEDPRNYLTFFCIGNREVKKSGAYEPSETPEPDSDYIRAQEARRFMIYVHSKMMIVDDEYIIVGSANINQRSMDGARDSEIAMGAYQPHHLATREPARGQIHGFRMALWYEHLGMLDETFLHPESEECVSKVNRMADKYWDLYSSESLERDLPGHLLRYPIGVASEGDVTELPGAEHFPDTKARVLGTKSDYLPPILTT
What is the function of this protein?
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.  Plays an important role in various cellular processes.
What are the official names of this protein?
Phospholipase D alpha 1, PLD alpha 1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. C2-PLD subfamily.
Protein: SYR_PHEZH
Sequence: MSDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIATAVAGRLQGDPRLASVEIAGPGFLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDYGGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHFGDWGYQMGLLIGAVCDEDAEIRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQAHKPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDDQGARIVRVAREGDKRELPPLLVVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQADHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTREGGVLKLADLIEMTRSKARERLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLLYQAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHAYRLSQAFSKFYAACPILAAPPPVRGSRLTLAQATLRQLELALDILGIAVPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.