PharMolix/UniProtQA huggingface dataset:
Protein: URB2_SCHPO
Sequence: MSLQTLTKRIRDKNGSREDQIDLANKLFRGEVDVYFPNKEEFIINFLLDRLKENSNLTCVNIGYWQLFLNIWKSDKLSGSFRVSAIRRQSLYPIILNAFEYLIKEFKKDVFLKISDVFVCVYSNLNILYISRSFPDQISLLFSRYCYLIASKIDDLLDSHPNEVFKETLICVIQSAVHSQASSTKAQTQFLHQTLGSILALLCKTQKGDPYFSFLNAVLMKCVLTQHTLDVLLLTKKDSSMTLCSLLNAISFEPINLKAIPLFFIICADSINFHLSSVEKSISQQKASELMYKLFSEHIAFLLSLKNLPEEATLDCMLSICQVFENDNLHRGHSDEYTFAMLEQLLELSVKTLRQNTCWSTSWEMLSSLLAIDFDVLLPHSKILWECIKSVSHQDDIHALKFLKRWVRASAKARILDSFCIDWHLNVQTMSERSILTNRDFITSFSAVAEVSLSQISIKKLVTWLMSSESIMSENSNRFVVYYSLCKSLKRESYPAHLVPNFELFTRSIFNASLKNFNILDERSQALLCMCQISHVQFFSSDMSISASVGMKTLFEDLMAEKSRGLSSTVWSLQLLLCYLEQCLRLNTLHEDTTFPMRVVNYALEYSSKALDKFAENSHLILLDMVDVGKPDLVLTLLCRWLHMVHLYSSRTSITSWIYSIASKFYFIDSLNLETKDSVLESNWERFISSTETYELDSIRDSLIDCLIRLLCYSSNNAIDPVSAPGNLDFDNSAELCSSLTRFTPKNIDFVLKSLIHIPIHSITKNQRTRLLNLLIIHEKLLSDKDNSAHISLRKIIYTLMKTPCSSGFYRDPKIIIDLMQFGKTDLSFHKVHVLIMRSWIQHLDEGNKSEVILKLLQLILADFRELPLETITLIFNALVDSLPTSKHIKNSNDILSSVFTINDMLIDEMTAYLSKKESLCSGTFSCLLACCNSVLRTQNLTSESLNKLHILKVGIEEKAISLKLNELPFLENWILFQCLLSFGGDDFLKVVAYMVYYRRTVGEMSFRVSDFELALSRLSTNDADYAILNILNLLTSNECDEFDYSVLMKVVGVFANYSDCFQRNRHLVHMVLLCCTHVFYNQTLKPATLIDSALDVFLCFVQKTSKFISLDSFNTILTALSTILNLKELECEPKDHANLILKIIQILNGLLFNHRSYMSGRFHVFYSILKSLLYSMVQHDSEMKKIKGIALMNFYKPKKVPIHVVQSFCRLLTTWMNPNLMHDSNKKNSSLTDAERLFVKATTKHFVFLLTDFMSAQTVYQIDIQVKELLTNCFYNVYENLSNHEKQMALVAMNAPSKSLYQKFVNDYLIFAKWNEA
What is the function of this protein?
Required for 27S pre-rRNA processing.  Has an early role during 60S ribosomal subunit assembly (By similarity).
What are the official names of this protein?
Probable nucleolar pre-ribosomal-associated protein 2, Ribosome biogenesis protein urb2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus, nucleolus.
Protein: MEI4_SCHPO
Sequence: MVENQGNVEAHGKPKKVILSLSLKESSKINDSQNVSNVSSKEKCETEALLREENKENLSSDSIRQMIFGDEMAGFVDTGEKPPCSYATLIGLAILQSHNKQLTLSGIYTWIRNTFRYYLNHDGGWQNSIRHNLSLNKAFIKVEKPKGKTLKGHYWTIDPDHMQNFVSVRLHRSHSTDSNSKKRPSSKCHEIKPLTTREIPLARKRSRLNSFNSSTSTSGSSSNVAAEVSNDASQPSNQDSSLNSNIVKPPLPPSNVQSNSSSSENVPKPNAETQEDLPTIDAHESSLYENVNDSRLYEVPACRNMALNTGYSDADPGYLRTSFRSNSHNSLPYSANEEEDVLQADFLVSQQSSMVSSYVSSRDPHSMPYYRREPIPLRPSSRFYEYTRPTYGRTDTSCSAPGAFCSTQINSPSSYINYSKCAPSSPTLSLQKHREHVKSLLYVPDLTPSFDGSDPWNPSSQLLSEPLFDQHSFQSSLDDLMSVTCFRDSPELNHESSGYSSAPLMPSNRAFINDFSL
What is the function of this protein?
Functions as a meiosis-specific transcription factor.  Binds to the 5'-GTAAAYA-3' consensus sequence of the promoter of the spo6 gene.
What are the official names of this protein?
Meiosis-specific transcription factor mei4.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUT_RICCK
Sequence: MTITQFKIQKLENFFGSLPKYATEHSAGMDLIAANKQPIIIKIGEIQLIPTGIAIALPDLFEAQIRPRSGLAVKHGITVANSPGTIDSDYRGEIKVILINLGKEDFIIEKGMRIAQMIISKYERILWKESNTLEETVRGSGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: LON_CAUVC
Sequence: MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).  CcrM is an important target of the Lon protease pathway in C. crescentus (By similarity).
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB_HALDI
Sequence: SVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RADB_METTH
Sequence: MKKLRDMGENRRIPTESSIDRILGGGVERRTITQFYGPPGSGKTNITIKLAVETARRGKNTVFIDTEGGLSVERIRQVSGDIFDRVADSIIVFEPSSFTEQGEALQRTFSFLKTHGDSTDLVVLDSAVALYRLKEGNASSFNLDLGRQMFLLLQMARRFDLAAVITNQIYSITGDDGREYVSPVGGTLLRYWSKVMVELEMGERPGERFAVLRRHRNRLEGSRVGFRIVADGIL
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: KEFF_SALTI
Sequence: MILIIYAHPYPHHSHANKQMLEQAGTLENVEIRSLYHLYPDFNIDVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLWAVTTGGGENHFAIGSHPGFAVLSQPLQATALYCGLKWLPPFAMHCTFICDDDTLQAQARQYKQRLLAWQEVNHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PPR1A_MOUSE
Sequence: MEPDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNSLLKSTLSMSPRQRKKMTRTTPTMKELQTMVEHHLGQQKQGEEPEGATESTGNQESCPPGIPDTGSASRPDTPGTAQKSAESNPKTQEQCGVEPRTEDSSAHMLPLDSQGASLV
What is the function of this protein?
Inhibitor of protein-phosphatase 1.  This protein may be important in hormonal control of glycogen metabolism.  Hormones that elevate intracellular cAMP increase I-1 activity in many tissues.  I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA.  Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B).  Does not inhibit type-2 phosphatases.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1, I-1, IPP-1.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 1 family.
Protein: MNME_BEII9
Sequence: MTHFAQAEPASLSHAATLETIFAPASGQGRSAVAIVRVSGPKAGFLLGALAGYCPEPRRATLAILHDPENGEALDEALVLWFPGPKSFTGEDCAEFHVHGGRAVMAGLLAALGRFEQVRPAEPGEFTRRALLNGKLDLAEVEGLADMIEAETEWQRRQALRQMRGALSRQAEMWRQALLEALSLAEAEIDFSDEADVPPETSRRVAALIEPVLADLRAELGQARAGERIREGLSIVIMGPPNAGKSTLLNALARREVAIVSEIAGTTRDLIEVHLDLKGCAVVLTDTAGLRDNADKIEQIGIARAYERGREADLVLWLSEAEAPVAPPENLGMEVWPVFTKADRVEPLENREGLAISATSGLHLGRLVEAIADFAGKLAPSGHAGLITRARHRQAFERAAAALDRCIREASPVELLAEDLRLAAQALLSLTGRIETEEILGEIFARFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_LISW6
Sequence: MGQIIDGEKLAKEIQERVTTEVAELAKIDKKPGLAVVLVGDNQASRTYVRNKQKRTEEAGMKSVLIELPETVSEEKLLEVVEELNTDDTIHGILVQLPLPKHISEEKVIDTISYDKDVDGFHPVNVGNLFIGKDSFVPCTPAGIIELIKSTGTQIEGKRAVVIGRSNIVGKPVAQLLLNENATVTIAHSRTKNLPEVAKEADILVVATGLAKFVKKEYIKPGAIVIDVGMDRDENNKLCGDVDFDDVIEEAGFITPVPGGVGPMTITMLLANTLKAAKRIWKMN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYE_BACP2
Sequence: MGNEVRVRYAPSPTGHLHIGNARTALFNYLFARSQGGKFIIRIEDTDQKRNVEGGEESQLRHLQWLGIDWDESIDKDGGYGPYRQSERNDIYKKYYDELLEKDLAYKCYCTAEELEEEREAQIARSEMPRYSGKCSHLSKEEEDKLIAEGREPSIRFRVPKGEIIKFDDMVKGEISFETDGIGDFVIVKKDGTPTYNFAVAVDDHLMKMTHILRGEDHISNTPKQIMIFNAFGWDVPLFGHMTLIVNENRKKLSKRDESIIQFIEQYKNLGYLPEALFNFIALLGWSPVGEEELFTKEQFIDIFDVNRLSKSPALFDMHKLKWVNNQYVKALDLDQVVALTLPHLQKAGKVSEQLSDEKNTWVRKLIALYHEQLSYGAEIVELTELFFKEQIEYNQEAKEVLAEEQVPEVMASFAGQLERLESFTPDEIKAAIKAVQKETGHKGKKLFMPIRVAVTGQTHGPELPQSIELLGKETVLNRIKQI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROL_SALNS
Sequence: MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQVVSEIIAALPPSTQRLQGDVYT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA2_BACLD
Sequence: MRSYEKSKAAFEEAQRVMPGGVNSPVRAFKSVNMDPIFMERGKGSKIYDIDGNEYIDYVLSWGPLILGHSNEKVVKEIQKAAEHGTSFGAPTELETELAELVIDRVPSIEIVRMVSSGTEATMSALRLARGYTGRNKIVKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPESIAKNTITVPYNDLESMKLVFQEFGDDIAGVIVEPVAGNMGVVPPVKGFLEGLRELTETHGALLIFDEVMTGFRVDYNCAQGYFGVTPDLTCLGKVIGGGLPVGAYGGKAEIMEKIAPSGPIYQAGTLSGNPLAMTAGLETLKQLTPESYREFSRKADRLEKGISEAAEKNGIPCTFNRAGSMIGFFFTNGPVINYDTAKQSDLGLFAEYYKGMADEGVFLPPSQFEGLFLSTAHTDDDIEHTIKAAERVFERISRSR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BURO1
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEASS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: OGFR_MOUSE
Sequence: MDDPECDSTWEDESEEDGEDGQADDTTDEDTGDDDGDAEEARPSLFQSRMTRYRNWRAMQDMQRYRHNYPDLTDQDCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRERLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHKLPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPSQEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPKESKKRKLEGNRQEQVPGEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPCLVARVANEVRKRRKVEEGAEGDGVASNTQVQASALSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP
What is the function of this protein?
Receptor for opioid growth factor (OGF), also known as Met-enkephalin.  Seems to be involved in growth regulation (By similarity).
What are the official names of this protein?
Opioid growth factor receptor, OGFr, Zeta-type opioid receptor.
What is the protein family that this protein belongs to?
Belongs to the opioid growth factor receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus.
Protein: COAA_STRZJ
Sequence: MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMGD_BACSU
Sequence: MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETKSYLELVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDGLRTGLSALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLYMMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNLHGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQQLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPIFFSARTSGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS
What is the function of this protein?
Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles (PubMed:28956599).  Has both 2-methylcitrate synthase and citrate synthase activities.  Catalyzes the condensation of propionyl-CoA and oxaloacetate to yield 2-methylcitrate (2-MC) and CoA, and the condensation of acetyl-CoA and oxaloacetate to yield citrate and CoA (PubMed:8759838, PubMed:28956599).  Has 2. 3-fold higher activity as a 2-methylcitrate synthase (PubMed:28956599).  Catalyzes the formation of either (2S,3R)- or (2R,3S)-2-methylcitrate (PubMed:28956599).
What are the official names of this protein?
Citrate/2-methylcitrate synthase, 2-methylcitrate synthase, 2-MCS, MCS, Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: VSPA_BOTJA
Sequence: VIGGDECDINEHPFLAFMYYSPQYFCGMTLINQEWVLTAAHCDKTYMRIYLGIHTRSVANDDEVIRYPKEKFICPNKKKNVITDKDIMLIRLNRPVKNSTHIAPISLPSNPPSVGSVCRIMGWGAITTSEDTYPDVPHCANINLFNNTVCREAYNGLPAKTLCAGVLQGGIDTCGGDSGGPLICNGQFQGILSWGSDPCAEPRKPAFYTKVFDYLPWIQSIIAGNKTATCPP
What is the function of this protein?
Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet aggregation through its interaction with GPIb (GP1BA/GP1BB), and activates factor VIII (F8).
What are the official names of this protein?
Thrombin-like enzyme bothrombin, SVTLE, Factor VIII activator, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP, Venombin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
Protein: LAADH_SYNY3
Sequence: MVIRSGKTNLNPPCALMAPSSSCDCIIVGSGLSGLIAARNLSRVNYSVLVIEAQERLGGRMYGEYLPSGQWIDRGGQWVGPTQDRFLALLNEYNIERFPSPADGLKVLLFDGKRYEFDGFFQGVFQGEAPKISSDEWNDAMVAWEKFNTLAQSLDEQHPEATPENKKLDSQTFADWIKENTHTAFGHWYFSYMCRAVGFLGPAEPSQVSLLHILWGHKSASQGENPEAELLHGGAGQIPQKIAAELGNSILLGEPVIHIAQDDKGVEVTTTTGKYQGKFAIVATPPHLAGRITYSPPMPPLRQQLTQRVPMGTCCKLLISYDRPFWREKGLAGIGLGNTTWIELCADSSDPTTGVGVIASFVVGDRYGKWIAMGEAERRQGVLSDLALYFGEEALSPETYDEVDWPSEQWVGGGYAAFMPPGVWTSFGQALSAPVGRIHWAGTEIAPRWAGFFDGAIRTGEAAAKAIIGLL
What is the function of this protein?
L-amino acid dehydrogenase with broad substrate specificity.  Catalyzes the oxidative deamination of various L-amino acids, L-Arg and L-Cys being the best substrates in vitro.  Likely functions mainly as an L-arginine dehydrogenase in vivo.  Probably feeds electrons from L-arginine oxidation and also from the oxidation of other L-amino acids into the respiratory electron transport chain associated to the thylakoid membrane, and does not directly interact with molecular oxygen but donates electrons to the plastoquinone pool.  Cannot use D-amino acids as substrates.
What are the official names of this protein?
L-amino acid dehydrogenase, L-amino acid:plastoquinone oxidoreductase, L-arginine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane.
Protein: PCKA_ECO5E
Sequence: MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTKQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVSEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANSP_EIMTE
Sequence: MADLFSGLVGGVVGAVAAADLPAEGERAPRPAPGTAWTCCCSKLQEGARELEGFVQQLSFVAGKLACCLRVGAEQLARCAAEGRLPSSSSSSSCCALLQLEKQDLEQSLEAGKQGAECLLRSSKLALEALLEGARVAATRGLLLVESSKDTVLRSIPHTQEKLAQAYSSFLRGYQGAAAGRSLGYGAPAAAYGQQQQPSSYGAPPASSQQPSGFFW
What are the official names of this protein?
Sporozoite antigen.
Protein: RS13_LISMC
Sequence: MARIAGVDVPREKRIVISLTYIYGIGKQTAKEVLAEAGVSEDTRTRDLTEEELGKIREILDRIKVEGDLRREVNLNIKRLIEIGSYRGMRHRRGLPVRGQNTKNNARTRKGPSKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MURQ_ECO81
Sequence: MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSSTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDADEAKKCLDQHGGFIRKALEKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RL22_PROM4
Sequence: MVESSSSKTKFAQAHGRYIRGSASKVRRVLDQIRGRTYRDALIMLEFMPYRSTGPITKVLRSAVANAENNMGLDPASLVITRATADMAPSMKRYRPRAQGRAFAIKKQTCHISISVAPSSESTNSEASD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PROA_RHILO
Sequence: MLKLHEKSGDDTVALMADIGRRARAAARPLAIAPTAAKNAALLAMADAIVARQQDILDANAIDVSNGEEAGLSASFMDRLKLTPARIRAMADGIREIAELKDPVGDVIAAWERPNGLRIERVRTPLGVVGVIYESRPNVTADAGALCLKAGNPVILRGGSDSLNSSAAIHACLVEGLKAAGLPEDAIQLVPTTDRAAVGEMLKGLGGALDVIIPRGGKSLVGRVQSEARVPVFAHLEGICHLYIDRSADLDMAVKIAVNAKMRRTGVCGAAETLLVDRAVASTHLVPILDALRAAGCEIHADQEVLKVFFDAKPATDADWVTEYLDAIIAVKLVDGIGGAIEHIETFSSHHTEAIIAEDPKAVERFFNEIDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA1_PROMA
Sequence: MASMNTHKPDWLRVKAPQHERIGYVADLLSDLNLNTVCQEASCPNIGECFAGGTATFLIMGPGCTRACPYCDIDFDKSVRSLDPSEPERLGEAVKRLGLKHVVITSVNRDDLEDGGASQFVSCIDAVRASSVETTIELLIPDFCGNWDAFKKVMNASPNVLNHNIETVPRLYKRARPQGLYKRSLELLRRVRQESPNVYSKSGLMVGLGETDDEVLQVLSDLHDNNVDIVTIGQYLSPGTKHLPVDRFVTPDQFQKYKEEGQTRFGFLQVVSSPLTRSSYHAGEVKRLMQIYPR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 1, Lip-syn 1, LS 1, Lipoate synthase 1, Lipoic acid synthase 1, Sulfur insertion protein LipA 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.