PharMolix/UniProtQA huggingface dataset:
Protein: TRUB_RHIEC
Sequence: MSKPRKPKGRPISGWLILDKPMDFGSTEAVSKLKWLYKAQKAGHAGTLDPLASGMLPIALGDATKTVPYVMDGRKIYEFTVSWGEERATDDLEGDVTQSSERRPTEQQIRDILPRYIGTISQVPPQFSAIKIAGERAYDLARDGEAVEIPSREVEIFRLTLLGCRDANTAHFEVECGKGTYVRALARDFGRELGCYGHISGLRRTFVAPFSEDAMVPLANLVALEAIEDMDERLAALDALLIDTCEALSALPHLVINDDQAHRLKMGNPILVRGRDAPIAESEAYATARGRLIAIGEIGQGEFRPKRVFA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CAPSD_RCNMV
Sequence: MSSKAPKKSKQRSQPRNRTPNTSVKTVAIPFAKTQIIKTVNPPPKPARGILHTQLVMSVVGSVQMRTNNGKSNQRFRLNPSNPALFPTLAYEAANYDMYRLKKLTLRYVPLVTVQNSGRVAMIWDPDSQDSAPQSRQEISAYSRSVSTAVYEKCSLTIPADNQWRFVADNTTVDRKLVDFGQLLFVTHSGSDGIETGDIFLDCEVEFKGPQPTASIVQKTVIDLGGTLTSFEGPSYLMPPDAFITSSSFGLFVDVAGTYLLTLVVTCSTTGSVTVGGNSTLVGDGRAAYGSSNYIASIVFTSSGVLSTTPSVQFSGSSGVSRVQMNICRCKQGNTFILG
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 31-34 nm in diameter, and consisting of 180 capsid proteins.  Plays an essential role in virion formation by interacting, via its N-terminal region, with the bipartite viral RNA genome and specifically with the 3' terminus of RNA-1 and the TA element on RNA-2.  Participates also in symptom development, viral RNA accumulation and systemic movement within the host.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the icosahedral plant coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ATX2_DICDI
Sequence: MSQSKDKKKFVGGGGGGGGNNSGGGGYGSPKHNNNNNNRNSSNNKSPHQSHHNQQHHQQQQQQQQQQQQQQQQPFDSLTAMKERTVFMSMSLVGQNVSVTLKNGDVYEGILHTTSTSTGSSGGGWGVALKMARKKDTNNRVITTLPLPLVIIEAKDFLQITATGVVLDHYRDSFMNRDQQSFITDTELSGFDGNLKERELTPWTPDPSVGESLDDFAANSEAKKPANWDQFETNEKLFGVRTTYEEEIYTTRLDRDSEFYKINQSVAEKKAQEIENEKSGNIHLLEERGFVEGADYDEEERYSSVVRKGLLPTSTTSTTTSPPTQNPTPSSSVYIPPSKRNNNNNTPSTPSVTSPPIVDKKHQQTHQDKKQTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQPTTTATATASTSTSTTTTTNESPSSSSTSSTPSTPSTPKNITTTTATTSTNNTPTATNTNVNSPLGDRESPTISKLRLHQSTIDQDVMGSPRENLSPRSVAYTRYRQILSEPTNKSMNKSGSNISTTPVNGSGNVGPNGTPLLSSVHSDQAPKSPVPTIVSNHGLVKALSLELATPTVPEKFVNDFNNFKLKINNVDRGSETQGLKSFSSNLVIKSKSRPGSPLIGSGSPRPTPTQLSLSGSSTSTNTSTTSPPTTNTTTTTTTATNSTTPSTTEDDKSTTTPITTTILTENKSDDKEKEKEKEKEKVDEKEKEKEKEKSDEKDKDQSSTLVEKKDESSSSSNTTTTTTNTTNNNNNNTTTVTKLSKLKLNPNAKEFVPVVVNKPQPSFKSTTESNTDSVTPINEIYYDSMRKRQLQPESPDQVSLYWVDPFYPRYEEDPYAAAYQMRAHHHMVGHQPPPQLQFNPQFYSQQGHPQLQPHHHMVPPQLQQVPPGVNVHTMKPPGSLQPGGGGVVQPQGIVQPQGIVQPQGGVVQPSAGGAPKTMYQQQQQQQQQTGQPGGPMGVQRGGHLPPQQQPQQQQQQPPPQFIQGIPPGANLVISNGPPNQPFVFQGAHPPYAVPHPQYPMPPQGIQGGNKRFYQPPPQGYPQVQPMIIPQQGQVVSQNSPQQDSPSNRLNQQVPPYSYMTHPPRGYHPNENQYH
What are the official names of this protein?
Ataxin-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the ataxin-2 family.
Protein: ATPF_CUSRE
Sequence: MKNVTDSFLSLGHWSSAGSFGLNTDILATNLINLSVVLGVLIFFGKGVLSDLLDNRKRRILKTIQNSEELGVGAVEKLEKARARLRKVKTEAEQFLVNGYFDIEQEKLNLIKSTYNTLEQLENDKNENLRFEQQRVIYQVRQRFFQKALQRAIGTLNGCLNNELHLRTISANIGMLGTIKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, plastid, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: RPOB_ENT38
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIKSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVVYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALQYTTEQILDLFFEKVIFEIRDNKLQMELLPERLRGETASFDIEFDGKVYVEKGRRITARHIRQLEKDDIKLIEVPVEYIAGKVAAKDYVDASTGELICPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGAYMSETIRVDPTSDRLSALVEIYRMMRPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDAIEGSGILSKEDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANTNLDEEGRFVDDLVTCRSKGESSLFSNDQVDYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTIIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKQQEEVAKLREFIQRAYDLGTDVRQKVDLNTFSDDEVLRLAENLKKGMPIATPVFDGAKESEIKELLQLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNMG_BACAH
Sequence: MGYNAGSYDVIVIGAGHAGCEAGLAAARMGSKTLMLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADKFSYQHELKKTIEETPNLTLFQGMVERLIVEDGECKGVITQAGAEYTAKTVVITTGTFLRGEIIMGDLKYSSGPNNQQPSITLSEHLEELGFDLVRFKTGTPPRVNSNTIDYSKTEIQPGDDKPRAFSFETTKFIMDQIPCWLTYTSTETHRLIDENLHRSAMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQRDMLRTIPGLENVEMMRTGYAIEYDAIVPTQLWPTLETKKIKNLYTAGQINGTSGYEEAAGQGLMAGINAACRSLGKKEVILGREDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEVGHEIGLITEERYERFTNKKLQIEQEKERLSSIIIKPRPEVQELIRNIGGSELKDGIRASDLLRRPEMTYEHIHLLVPSEVELSDEVKEQVEIQIKYEGYIEKSLQQVERMKKMENKKIPVDIDYDAISSLASEARQKLKDVRPLSMGQASRISGVNPADISILLVYIEQGKIARVSNQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODFP4_RAT
Sequence: MESDLTVEESETIKTRSRRPLTEHRRHSLLPLQWKLAHSSRWMAQVVASEFSLLAFLLLLLMVFSKKWLYPSKSRFHQRYPQNITKRVYTSIHSMSTGLLYICISKSCLSSDNEEDNFKMWTIHPAFGVAKISFILAVGLGFVLTVWLHLPYLPCLQRMPFFGLIGIILSFCEVTLIFLTLLLFPVNLWIYELKKNISVPIGWSYFIGWLVLILYLTCGILCYLNHKNFWSLIMSSSSINATCSSSVPVSLMNTSQISKSQADILDPTQDDQKPLSSDNIALPPNPDTTD
What is the function of this protein?
Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.
What are the official names of this protein?
Outer dense fiber protein 4, Outer dense fiber of sperm tails protein 4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHED_CHAGB
Sequence: MKLCALFAGAVISTSAVAASWEYAWPEEWHQEWPLDEQGPDAWSSSECTVSRLDAFEMEKGRKPVFFSTDPLDDPEAPKMLPLNSTGGEQWEFDGVSEDGQMAFCFGFYRDPNYAILGTGNLRLSAEFSRPNKTRFVRVDYPSSSTVTSCPWGTRGVWKGADYSYTFEVTRDIKVARIGVDAPDLKGSVVMRSVMPPRYPDGSTYPNKEASTEVVPYFRWLEAIPAADVRVDVVMDGQPYRWSGLGGHERLWTAFSWFTCLQAMTAVRVKAGPFAAVHGSFVSAIDKGLYRPSTVLAENDEVIFSTTLHEPSDTEDYAVFTKTYGGRVSGNLKEKATGYELVMVSPSAKKQWSFSITNEAIGFEYMLGEGVGGTGFSGRAVGGSIGLKQYFGPSFAETLEFPKRSYLFKSNYVDAVPEEKGEL
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of chaetoglobosin A which has a unique inhibitory activity against actin polymerization in mammalian cells (PubMed:23611317, PubMed:33622536).  Chaetoglobosin A and its intermediates are involved in the morphological differentiation of C. globosum (PubMed:33622536).  The first step of the pathway is the synthesis of prochaetoglobosin I via condensation of one acetyl-CoA, 8 malonyl-CoA, and a L-tryptophan molecule by the PKS-NRPS hybrid synthetase cheA, followed by reduction of backbone double bond to install desired geometry by the enoyl reductase cheB (PubMed:23611317).  Further multiple oxidation steps performed by the cytochrome P450 monooxygenases cheE and cheG, as well as by the FAD-linked oxidoreductase cheF, lead to the formation of chaetoglobosin A (PubMed:23611317).  Depending on the order of action of these reductases, distinct intermediates can be identified (PubMed:23611317).  Within the pathway, the cytochrome P450 monooxygenase cheE catalyzes a stereospecific epoxidation on prochaetoglobosin I, cytoglobosin D, and chaetoglobosin J intermediates (PubMed:23611317).  The FAD-linked oxidoreductase cheF performs dehydrogenation of the C-20 hydroxyl groups in the 20-dihyrochaetoglobosin A and cytoglobosin D intermediates (PubMed:23611317).  Finally, the cytochrome P450 monooxygenase cheG can catalyze the stereospecific dihydroxylation of prochaetoglobosin I and prochaetoglobosin IV at C-19 and C-20, respectively (PubMed:23611317).  The Diels-Alderase cheD may play a role in the post-PKS-NRPS biosynthetic steps catalyzing Diels-Alder cyclization (Probable).
What are the official names of this protein?
Diels-Alderase cheD, Chaetoglobosin A biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.
Protein: ENGB_METFK
Sequence: MPLFQNATFHISAHNLSDLPAPAGIEVVFAGRSNAGKSSALNTLANHNRLAFVSKQPGRTQLINFFSLGNDRFLVDLPGYGYAKVPEAVRKHWQLTLASYLSQRPCIGGLVLVMDCRHPLTPLDRQMLNWYSPSGKPIHALLTKADKLSRQAANQTLQQVRKELEASWGNCSVQLFSSLKKQGVEEAETVIGRWLFAPEDDVPDAVA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NU6M_PANPA
Sequence: MTYVLFLLSVSLVMGFVGFSSKPSPIYGGLVLIVSGVVGCTIILNYGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGEGPGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AROC_HELAH
Sequence: MNTLGHFLRLTTFGESHGSVIGGVLDGMPSGIKIDYELLENEMKRRQGGRNAFTTPRKEDDKVEITSGVFEDFSTGTPIGFLIHNQRARSKDYDNIKNLFRPSHADFTYFHKYGIRDFRGGGRSSARESAIRVAAGAFAKMLLKEIGIVCESGIVKIGGIEAKNYDFNHALKSEIFALDKEQEEVQKTAIRNAIKNHDSIGGVALIRARSLKRNQKLPIGLGQGLYAKLDARIAEAMMGFNGVKAVEIGKGIESSLLKGSEYNDLMNQKGFLSNRSGGILGGMSNGEEIIVKIHFKPTPSIFQSQQTIDIKGNECECLLKGRHDPCIAIRGSVVCESLLSLVLADMVLLNLTSKIEYLKTIYNEN
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UPP_PSYIN
Sequence: MKVIEVKHPLIQHKIGLMREADISTKRFREIAREVGSLLTYEATKNLELETVKIQGWNGEVEVQQIKGKKATVVPILRAGLGMMDGVLEHMPSAKISVVGIYRDEKTLEPVPYFQKLVSNIDERLAIVVDPMLATGGSMISTIDLIKKAGCTRIVVLVLVAAPEGLKALEAAHPDLEVYTASIDDHLDEQGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SRP19_HYPBU
Sequence: MSKEYRGRRIVLWPANIDSTLSRSEGRKIPLRDAVRKPRVEEIVEAANRLGLNPTVEEAAYPRSWWEQRKRVVVDKVGSKLNTLRMIAQEVKKLREERRRLGK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACAP2_CHICK
Sequence: MKVTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCLANKQFMNGIRDLAQYSCKDALVETNLTKFSDTLQEMINYHNILFDQTQRSIKAQLQTFVKEDIKKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLTFFHQGYDLFSELGPYMKDLGAQLDQLAVDAAKEKRDMEQKHSTIQQKDYSGDDTKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKQEKKSSPSTGSLESGSETKEKLLKGESALQRVQCIPGNAACCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDSWEPELLKLMCELGNDVINRIYEAKLEKMGVKKPQPGSQRQEKEMYIKAKYVERKFVEKQPAAAVSPLESRTKVLPQSQEEKRHSAPEKSFLAIEQGAASPRVRSSDSGIQQSVDDSREHLASTISANSLYEPEGEKQESSVFYDSRQLNPGLHLYRAAFEKNLPDMAEALAHGAEVNWVNMEENKATPLIQAVRGGSLVTCEFLLQNGANVNIRDMKGRGPLHHATVLGHTGQVCLFLKRGANQHATDEDGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDEIYQDIFRDFSQMASNNPEKLNRFQQSDSQKP
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
What are the official names of this protein?
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Centaurin-beta-2, Cnt-b2.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: ISPD_CLOBH
Sequence: MSKNSVIIVAAGKGKRMNSSISKQFLQIKNKPILYYTLSKFSTHESIDEIVLVTLEDKIEVCSDIIDKYNINKVSKIVPGGKERQDSVYNGLKGVSKDCEVVLIHDAARPFVTSDIIENGIRYTNQYGAAACGVIPKDTIKIKNEKGFAIDTPNREDLFIVQTPQCFNYNIILSCHEKLKKHNKKVTDDTMVLENYGKSVYLYEGSYSNIKITTPEDLILGEQILEKLT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CP179_THYVU
Sequence: MDISISWVVIIVSVLSYLILMDKWRAAKLPKNIPPGPPKLPLIGHLHLLRGGLPQHLLRGITQKYGPVAHVQLGELFSVVLSSTEAARQAMKVLDPNFADRFVNIGSRIMWYDSEDIIFSRYNDHWRQIRKICVSELLSPKNVRSFGYIRQDEMASLIRLFESSEGKPVNVSEEISKTVCTIVSRVAFGSAVKDQSLLLNLVKESLRMASGFELADLFPSSWLLNLLCFNKYRLWRMRARLDNFLDGFLEEHRVKKSGEFGGEDIIDVLYRMQKDSQMKVPITNNGIKGFIYDVFSAGTDTSAATILWALSELMRYPEKMAKAQAEVRESLKGKTNVDLTEVHELKYLRSVVKEALRLHPPFPMIPRLCVQESEVTGYTIPANTRILINVWSIGRDPLYWEDPDTFNPDRYDEVPRDIIGNDFELIPFGSGRRICPGLHFGLANIEVPLAQLLYHFDWKLPPGMTAADIDMTEKTGLSGPRKNPLILVPIIHNPTS
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents (Ref. 1).  Catalyzes probably the C3-hydroxylation of gamma-terpinene to produce thymol (Ref. 1).
What are the official names of this protein?
Cytochrome P450 71D179, Gamma-terpinene hydroxylase, Thymol synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RNY_STRPF
Sequence: MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARNESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LEC1_HYPCE
Sequence: QKACTMDYFPVCCQIVLGGGAYTAGNPCSCQGFVASKGTCDNPYPCPCTTEAQFPVCCTTQWGLVSATGNCACGCMGGVPVSDGPCPEVY
What is the function of this protein?
Lectin with specificity for complex N-linked glycans and O-linked glycans.  Has hemagglutinating activity towards rabbit erythrocytes that is inhibited by N-acetyl-D-galactosamine.
What are the official names of this protein?
Lectin-1, HCA.
Protein: HDRA_METMA
Sequence: MRIGVYVCHCGLNIAGVIDVSALEEMAGELEDVVLAREVQFLCSDSGQEGIIKDIKDNKIDRVVIAACSPRLHEKTFRHVMEKADLNPYLMEMVNIREQCSWVHADDPQMATQKAFDLIRMGVAKARFLRELSATSSKASRNVLIIGGGVAGIEAALNLAEAGFPVTMVERESTIGGKMALMNEVFPTNDCSICVLAPKMTEVQNHPNITLYTYSEVTDISGSVGKFHVRVTRKPRFVLEDKCKGCVDLCSEVCPVEIENPMNYGIGKSRAIYMPIPQSVPQVVLIDPDHCVGCGLCQLACPAEAVDYEQKPEEIEFEAGAVIVSTGYQLFDASRKKEYGFGKYPDVITNMQLERMLNSAGPTGGRVLVPSTGQPPESVAFIQCVGSRDKTVGNEHCSRVCCMAALKNSQMVKERYPGTDITIHYIDIRAAGEMYEEYYARTQGMGVDFIRGKVAEVYAGEDGRPVVRYENTLESRVEEEAHDLVVLSTGYEPSKAAEGIGRMLNLARRPDRFFASAHPKMRPVDAPVSGVFLAGCASGPKEIQVSIAQGSACASKVMQLLGTGELEADPMGAHVDPDKCIGCRTCVEVCKFGKISIVDKKAVVDEVSCYGCGDCSAACPVGAIQMRNFENEQILAQVRAATAHKSQCPFVVAFLCNWCSYACADLTGMSRIHYPTNIRVIRTMCSARINPEFVLEALKGGADGVLVAGCRMDECHYIHGNFDAKKRMDVLKEIIKEIGLDPKRLRTLWISAAEGERFSNTITEFVKELEEIGPIGSELKREYTATGLEEVAK
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
What are the official names of this protein?
Ferredoxin:CoB-CoM heterodisulfide reductase subunit A.
What is the protein family that this protein belongs to?
Belongs to the HdrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMGN_HUMAN
Sequence: MDLGKDQSHLKHHQTPDPHQEENHSPEVIGTWSLRNRELLRKRKAEVHEKETSQWLFGEQKKRKQQRTGKGNRRGRKRQQNTELKVEPQPQIEKEIVEKALAPIEKKTEPPGSITKVFPSVASPQKVVPEEHFSEICQESNIYQENFSEYQEIAVQNHSSETCQHVSEPEDLSPKMYQEISVLQDNSSKICQDMKEPEDNSPNTCQVISVIQDHPFKMYQDMAKREDLAPKMCQEAAVPKILPCPTSEDTADLAGCSLQAYPKPDVPKGYILDTDQNPAEPEEYNETDQGIAETEGLFPKIQEIAEPKDLSTKTHQESAEPKYLPHKTCNEIIVPKAPSHKTIQETPHSEDYSIEINQETPGSEKYSPETYQEIPGLEEYSPEIYQETSQLEEYSPEIYQETPGPEDLSTETYKNKDVPKECFPEPHQETGGPQGQDPKAHQEDAKDAYTFPQEMKEKPKEEPGIPAILNESHPENDVYSYVLF
What is the function of this protein?
Regulates the proliferation and differentiation of hematopoietic cells.  Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model.  May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
What are the official names of this protein?
Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein.
Protein: CH60_EXIS2
Sequence: MAKDILFSEEARRAMLRGVDALADAVKVTIGPKGRNVVLERKFGSPLITNDGVTIAKEIELEDHFENMGAKLVAEVASKTNEIAGDGTTTATVLAQAMIREGLKNVTAGANPMVIRKGIEKAVRRAVEELHAIAKPIEGKEAIAQVAAISAADEEVGQLIAEAMERVGQDGVITIEESRGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLENPYILITDKKISNIQEILPVLEQVVQQNKPLLIIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDISIVTGAELITEELGLDLKETQITQLGRASKVVVSKDNTTIVEGNGHSDSITARVGAIRSQIEETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKERKLRIEDALNATRAAVEEGIVAGGGTAFIHVTKAVESILAVTTGDEATGVNIVLRALEAPLRQIAENAGQEGSVIVERLKHEAQGMGYNAATDEYVDMIETGIVDPAKVTRSALQNAASVSAMFLTTEAVIADKPEPAGAPAMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CUPMC
Sequence: MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIESYTQFLQAETPPARRKSEGLQAAFNAIFPISSHNGLARMEFVSYHLSNPPFDVKECQQRGLTFHSALRAKVRLIINDRENPGKVKEVKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLQSEGAQLEFVPERLRGEVARFDIVDKNGRVVVEKDKRINAKHIRDLDSAGTKLISVPEDYLLGRVLAKNIIDPDTGEVIANANDELTETLLENLREAGVKDIQTLYTNDLDQGPYISQTLRADDTADQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEESYDLSRVGRMKVNSRLSRPSGEGSMVLQDEDILETIKILVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVKERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVENSKLTDQVDYLSAIEEGKYVVAQANATVDAEGNLIDELVSAREGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRPDKPLVGTGIERTVAVDSGTAVQATRGGVVDYVDAMRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDIVARGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGIVIDVQVFTREGVTRDKRAQSIIDDELKRYRLDLNDQLRIVEGDAFQRLERMLLDKTVNGGPKKLAKGAKLTREYLADLDKYHWFDIRPADEEVAAQLEAVKEAIEQKRHEFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGTPADIVLNPLGVPSRMNVGQILETHLGWAARGLGQRIGDMLKASAKAQELRPLLAQIYNESGKAEDLDSLSDAEVLELAGNLKKGVPFATPVFDGAHEAEIRRMLDLAYPDDIAKERGLTASKQQVTLHDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLDRY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AROC_STAS1
Sequence: MRYLTSGESHGPQLTVIIEGVPANLEINVADINEEMFKRQGGYGRGRRMQIEKDAIEIVSGVRNGYTLGSPITLIVTNDDFTHWKKIMGADPISEEDQDNMKRVITKPRPGHADLIGGMKYNHRDLRNVLERSSARETAARVAVGAVSKILLKQLDINFYSRVVEIGGVKDDLEYDLDTIKSNIDKNDVRVVNDEIAQTMRDKIDAAKKAGDTIGGVVQTIIEGVPVGIGSYVHYDRKLDGRIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYDTTNGYYRGSNHLGGFEGGMSNGMPIVVNGVMKPIPTLYKPLNSVDINTKESFKASIERSDSCAVPAASVVVENVVAFELAKALLEEFQCNHIEQLQSQIKERRLLNIEY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.