PharMolix/UniProtQA huggingface dataset:
Protein: Y3472_RHORT
Sequence: MKNIGQMLKQAQQLQTRMAEVQEELKAMDVSGQSAAGMCVVTLDGKGGVRSIKIDPSLVDPKETEVMEDLIVAAFNDAKAKVDEMVKEKMSELTGGLKLPPGMSLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Rru_A3472.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KR73_ICHVA
Sequence: MADRTPKRSADGLIHDAKPSKVTKNDRPPVIDFKRILAAKIAEKRGGPPVSAVSLIAASTVSTPAPVTYGSVGLPTRQLSDSDDDDEEDNATAKTHSVPIPVFKPPDQLTAPHTVKRKPTQPPTPTRPVHQAQATQRRPVVSYDTTGRRATTQDEITDAFGELDNELRRLAALTPVPGGWPESTRGERNQMVNPVGVKELPIVVQSITDRAIQIENRLEAQFHGATEMVKTVVPTVSVRGGVFTRHVITDTKRQPFLIEACEFIPSMIQEAPIPFRAVASKPFAAGTKLLTPKAGAPAVDLRAAPVLGKGYFGTVYKVGNLACKVQHGRVMPGVSNAISDVVEESLLGSRLQHPNIITFVKGFLYHGAVNTEAVCVSLWELGLMDLLSFTQQSFWQPGKDACDPLVKRYLARRFEKHTLLGLEHLHERGLMHRDIKSQNIFIFTNRGRLVAKLGDLGCCSKGAFCDAGGTRAYFPPETLAINVQCCASDMWAWGVTMWEVHTGRTPFWGGTDISMQKVFRYTGGFDNRAYNQLAVARHAMAAADSAVKPVPDLEGLMERGKVSLSPSFTDIMKSVLRLNPNDRATASDLLKSPRYTDESLTEGCECTDRKSLEKNAPEMIRLLEHNHLPPQKVIMTTDPHERDQLAEKERWGQVPMEVTGDFRPAPLYMPWLARADMGDDHTAKKLITLTPRDLVSVYPVVATKEYGVKEIRVYRPPEFSPTYDIVYLELKPTIDFEAIQSLMEGIQAIQKSIPYVVPVFHYTLGAHGTKRYMIYVTPAKRSITELNFDGETDDGTLLGAVILKQLISLAVAFRDNGINFITNMYNTHILYHDPRGVDIGPLKLDMVIYMLLHQTNNLNVYKLSSTDRTLRDPGDPVLKTCLAAYTYVKLLMSAPRALERLVPKTTISACKRFDDFFMIPTVKKISIPPDTKIKVPKLFSFIKIEPPQDISGGTVYASGTLS
What are the official names of this protein?
Protein kinase ORF73.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: UREF2_BRUSU
Sequence: MTMRTATITEFSSSYRSLPGLLHLLQFGDSALPIGGFSFSNGLESAIQQNLVHDKETLREFTLTAMNQAATSDGIALLTAHRAARADDRGALQVIDKAVFERKLNEETRLMTVRMGRKLCELSASIIDDRLNRDWLECIKTAETPGTHPVSLGLAFAALDVDGRDAFGAQQYGVATTILGAALRLMRVSFMDTQKILLEATSTVAPAYEEIADAGIEDMASFAPMVDILAAVHVKGHVRMFMN
What is the function of this protein?
Disrupting the ure2 operon has no effect on urease activity, or pathogen survival in BALB/c mice when inoculated by gavage, but confers slightly enhanced resistance to low pH killing in vitro.
What are the official names of this protein?
Urease accessory protein UreF 2.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA2_AQUAE
Sequence: MFPGGISMTELIIILAVILLLFGAGRLPEAGRALGEGIRNFRKALSGETEVKEVKAEDVKTEERKEEKKEEKEKVEA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA 2.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HXC13_MOUSE
Sequence: MTTSLLLHPRWPESLMYVYEDSAAESGSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAPHLHST
What is the function of this protein?
Transcription factor which plays a role in hair follicle differentiation.  Regulates FOXQ1 expression and that of other hair-specific genes.
What are the official names of this protein?
Homeobox protein Hox-C13.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECE_ARCFU
Sequence: MDISGMQINEVQSKLKEYYNVLKMARKPDWEEFSMTAKVALAVMFIVGFVGFVIYILMEILPGALK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MIAA_RICTY
Sequence: MIKKEIIILCGPTASGKSYLGHELAKAYGCEIINIDSMQVYREIPIITASPIQIYNTGIHYHLYNFLSITEDFSVIKYLKLASEKIREITARGKIPILIGGTGLYINLLVFGYNNIPDISQDVRVQVRNLHNEIGNIELWNKLEKLDPIAATKINHCDTQRLIRAYEVLMHTGKSIFSFHTAQKERILSDFNFKIIFLNPERKFLYKTCDERLDKIFKDKAIDEIALIKKQFTPKEYANLKAVGIKEIIAYLDGNLTLNDALNVAQMRTRQYAKRQVTWFTHQIQDKTILEYSTQEEFEQILRNLLFTLKS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NHR19_CAEEL
Sequence: MTTVFQTMPTFLAGLNIANFGAATSQFPKLESEITAPRQSMSTAFQKMPTFTSVISVPSIAAIAPQMPSVKPEKGVIGQCLICGEPSTGKHYGIVACLGCKTFFRRAVVQRQDTECKREKPCDVTTMARKACRACRYRKCLESGMSKEALQPRRDLIGCRRIRSRPSCSTSTPTPPRPQVEDKSQYLTLLENLTTIDDRLRKKKLEVVASRQAAVDLAVLAKQGCMSITDTSGPSTSRYVPGGTSPNGGDHKMMVMLGTDISVSTQSELLMMLEWTRTLPVFASLPVQDRSVILKRFAVHCLILEHGYYTAQANIDDVWLITNGTCMPRNVEKLEEGCKISVSADRRWRQEKLYKQMTDCCIDEVATPLRNLKLSPQEIVVIKIIVLFNCGCSSDYSEITEASRRIVLTFRNKVVSALFAYYESVGLQNYAERFGNLVLMLSGVSSAASSMLEAYQVMRLFKITPFDPLSQELLFNI
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-19.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_BURA4
Sequence: MSEKTVKVQLVKSLIGTRESHRATVRGLGLRRLNSVSELQDTPAVRGMINKVSYLVKVIA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: U6CC_CONCL
Sequence: MKFYLLLTAALLLTAVIIEAAPTDHQDEARDLMREERDDKSNCPISHPNYCSFTPVCCKHECLSNNKCSSSEFIPGQ
What are the official names of this protein?
Conotoxin Cl6.12.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_STRP8
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVAENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RMLCL_STRP6
Sequence: MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYADPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL
What is the function of this protein?
Could catalyze a 3,5-epimerization.
What are the official names of this protein?
Protein RmlC homolog.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Protein: ECOT3_LEIIN
Sequence: MPSLQDYHVPYPAAAPGQVRKVIYLPQQNPTVEQQHLRVQIIPGRHENCEDGRLYKLTGSVTEETLQGWGYSYYVVKLGDIYAAHRSSSDPARVTTFVALDENPVIAYNSKLPIVVYVPEGAELRYRVWTDDTSLVQSIQQQPEAPALPQPHLVPVTERQECPHELPRCGAPGEYVTQDCKTSMLSVEEVHRLSSSTPPLIPSAVRGSAHEAHAAPPLHSAELEERVCPVMEHLEVCPQNNGHEGREQPAEEASTLKRRSSSSSSSNPRHHSANEPSPSRPRLSSTEYWPHENSKTKRSPSATHKPRRSTDSAAIEEAGVGAPKKNRSSSSSASSKRKAEDNVYEKTMKNFWNRARSDSPRKASASSKKSGNGSKADP
What are the official names of this protein?
Ecotin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
Protein: HIS4_STAS1
Sequence: MIKLWPAIDLINATSVRLTEGKYDSEVKMARSAEESVLFYNQYQCVDRIHIVDLIGAKNQVSIESDYINQLRSLTDKPMEVGGGIRDRNTIDTYFNNGIDYCIIGTKGIEDLAWLSHMTQAFPNRLYLSIDAYRRQVKINGWEEDAGLDIFDLLQQVESLPLGGIIYTDISKDGKLEGPNFEITQQLVQATQKPIIASGGIRHQQDLAQLESIGVHAAIVGKAAHNATFWEGLS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ECODH
Sequence: MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCAL1_RHEAM
Sequence: VRANRCLKGWLDFRGNCYGYFRQELPWRKAEAWCRVVRGGCHLASIHTSEEHRAVAKFISQCRRGEEGDDVWIGLYHWNKSWSWIDGSKMHYSAWDDDDFSKGQYCAALEDSSGFLSWEDDACSERNAFICKCAA
What are the official names of this protein?
Rheacalcin-1, RCA-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Eggshell matrix.
Protein: TMM47_HUMAN
Sequence: MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY
What is the function of this protein?
Regulates cell junction organization in epithelial cells.  May play a role in the transition from adherens junction to tight junction assembly.  May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B.  During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity).
What are the official names of this protein?
Transmembrane protein 47, Brain cell membrane protein 1, Transmembrane 4 superfamily member 10.
What is the protein family that this protein belongs to?
Belongs to the TMEM47 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell junction, adherens junction. Note=Colocalizes with FYB1 at cell-cell contacts in podocytes.
Protein: SYY_SALAR
Sequence: MEILMASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVAKIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLIAAKRITESLFNGSLGELSEADFEQLAQDGVPMIELEKGTDLMQALVDAELQPSRGQARKTIASNAVTINGEKQSDPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSF1_ASHGO
Sequence: MYGDVANKLVLEAKRTDHLANGSATLQLPMFQDEMVRVILKEVSQLQRNAEYLKLQEDSGKLSKCQYFVTMLCMERNKRCLLAYQKTRSEILDAIAWENNGLDTMDLLSNKGHDSGNLSPYEQEYLREYSQLISDLTAGELMDIDLAGSLTPPSDVFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQADVERLIQQGYLQKL
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein PSF1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY2_RHIME
Sequence: MTEPTQLWGGRFKSGPSEALANLSRAPRSYFRLYKEDIAGSRAHASELKRAGVLDESEFSAIRAALEGIEADVGAGREEPIAADEDLHTFLERLLMARLGTLGGKLRAGRSRNDQTANNTRLYLRRMARELSQGVIAIEEALTEQASRHTETVMPGFTHLQPAQPVVLGHHLMAHAQSLLRDLQRFADWDRRFDRSPLGAAALAGSGIARRPDLSAIDLGYSAACENSIDAVAARDHVAEFLFICSLVAVDLSRLAEEICLWSSKQFSWVRLHDSYSTGSSIMPQKKNPDVAELTRGMSGTLIGNIAGFLATMKAMPLAYNRDLAEDKRSLFETIDVLELVLPAFAGMVGTLEFDVEKLREEAPKGFTLATEVADWLVGRDVPFAEAHEITGAVVRFCEERGHDLAGLTAEDLPGIDPRLHPEMLAALVLEKALASRNGYGATAPEKVREQIARFETALAECCAFAGGPIGGGAFAGAKDGAEEARRR
What are the official names of this protein?
Argininosuccinate lyase 2, ASAL 2, Arginosuccinase 2.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_RICAE
Sequence: MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVEMLKDRLGAKPLVIQLPVGIEENFKGIIDLIKMKAVIWKDEALGAEYFEEDIPADMKDKAEEYRAKLLDMVVELDDHVMEKYLSGEEVTAEEIKRLIRKGTISAAFYPVLCGSAFKNKGVQPLLDAVVDFLPSPIDIGIVKGMEVSTGEEKDFPISVTEPFAALAFKIMNDPFVGSLTFIRIYSGKIISGTTVINTVKNKREKIGRMLLMHANNREDIKEASAGDIVALAGLKDTTTGDTLSDIDQQVILERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFRVSTDYETGQTVIKGMGELHLEILIDRMRREFKVEANIGAPQVAYRETITKVCEIDYTHKKQSGGAGQFARVKIIFEPLKEVKDLKDEDKNKIFVFESKIVGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMQVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTANVPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANA_SALG2
Sequence: MAKALQGVMAALLTPFDHQQQLDSESLRRLVRFNIGQGIDGLYVGGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVSALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVLSVPLCRKPFAPVDEKYLPALKALAQQLMEEKA
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_ALBFT
Sequence: MADLNSLDVLIQALRRLPGVGVKSASRMAFHLLQHDRPGALALSRALQVAADQMRHCERCHTFTQADICATCLDPRRDASKLCVVETPADQSALERTGAYHGLYFVLMGKLSPLDGIGPKDIGLKGLFDRACDGTVQEVILATNFTAEGEATAHVISEGLKSRGLRLTRLARGVPVGSELEYVDLGTIAHALLDRR
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ATP8_SCHPO
Sequence: MPQLVPFYFINILSFGFLIFTVLLYISSVYVLPRYNELFISRSIISSL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: LIN7A_BOVIN
Sequence: MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells (By similarity).
What are the official names of this protein?
Protein lin-7 homolog A, Lin-7A.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: HMGB1_HUMAN
Sequence: MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE
What is the function of this protein?
(Microbial infection) Facilitates dengue virus propagation via interaction with the untranslated regions of viral genome.  In turn, this interaction with viral RNA may regulate secondary structure of dengue RNA thus facilitating its recognition by the replication complex.
What are the official names of this protein?
High mobility group protein B1, High mobility group protein 1, HMG-1.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Endosome. Endoplasmic reticulum-Golgi intermediate compartment. Note=In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to various stimuli such as LPS and cytokines involves a nonconventional secretory process via secretory lysosomes (PubMed:12231511, PubMed:14532127, PubMed:15944249). Secreted by plasma cells in response to LPS (By similarity). Found on the surface of activated platelets (PubMed:11154118). An increased chromatin association is observed when associated with the adenovirus protein pVII (PubMed:27362237).
Protein: AAEA_ECO81
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ITR2_SCHPO
Sequence: MDFNNIPLATIKSSDDKGKDFIVEMTTRPSETKKKVPFSEDMREIPSLPNEEEANATDPQANEVADENGEGFEAEKISSWIWVLSAVAGISGLLFGYDTGVISGALAVLGSDLGHVLSSGQKELITSATSFAALISATTSGWLADWVGRKRLLLCADAIFVIGSVIMAASRNVAMMVVGRFIVGYGIGLTSLIVPMYITELAPARLRGRLVIIYVVFITGGQLIAYSLNAAFEHVHQGWRIMFGIGAAPALGQLISLFWTPESPRYLLRHNHVEKVYKILSRIHPEAKPAEIAYKVSLIQEGVKVDFPEGNKFQHFFHSLKVLFTVPSNRRSLFIGCFLQWFQQFSGTNAIQYFSAIIFQSVGFKNSISVSIVVGATNFVFTIVAFMFIDRIGRRRILLCTSAVMIAGLALCAIAYHFLPADTTQNTNSGWQYVVLASIIIFLASYASGIGNIPWQQAELFPMEVRALGAGFSTAINWVGNLIISASFLTMMESITPTGTFALFAGFCFVGLVTSYFTYPELAGMSIENIHKLLEKGFWQAVKESTKRVRKGRIDEA
What is the function of this protein?
Transporter for myo-inositol.
What are the official names of this protein?
Myo-inositol transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LST_PHOPY
Sequence: MFASILGKIPQYSTISSKCSLKECRKVKKVENSDEIGEIIHRDFLDPFCNEYVLIGEEETSLGINYLQFEEEIRTFEIRDSDIIVASYPKAGTTWTQELVWLIGNDLDFKAAEEHLDKRFPHFELCTIVNFAKMTEMLGSTRPEYIGNSINYLRDLEGTRFIKTHLTYNLLPEQILNGNRKPKIIYVMRDPKDVCVSYYHHGRLIQGWRADFQNFSKVFLSEKIMFGSYWKHVLGYWEHRDKPNVLILTYEEMKKDLLSVIRKTAQFLDKKLNENKIPQLLKHLSFESMKNNRAVNQQDKIESRMKHKLVPEQGAFMRSGTSQNYKGEMSEELILKFDEWTKKSISGSSFVTEPIADLYLNTSQKSVPKM
What is the function of this protein?
Catalyzes the production of firefly sulfoluciferin from luciferin using the sulfo-donor 3'-phosphoadenylyl sulfate (PAPS).  Is also able to catalyze the reverse reaction, i. e.  the adenosine 3',5'-bisphosphate-dependent desulfonation of sulfoluciferin.  Can use either D- or L-luciferin stereoisomer as substrate.  Sulfoluciferin, which is not a substrate of P. pyralis luciferase, likely serves as a luciferin storage form in fireflies.
What are the official names of this protein?
Luciferin sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.