PharMolix/UniProtQA huggingface dataset:
Protein: RNFH_CITK8
Sequence: MSAKIVVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLAKNKVGIYSRPTKLADVVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: DXR_ZYMMO
Sequence: MSQPRTVTVLGATGSIGHSTLDLIERNLDRYQVIALTANRNVKDLADAAKRTNAKRAVIADPSLYNDLKEALAGSSVEAAAGADALVEAAMMGADWTMAAIIGCAGLKATLAAIRKGKTVALANKESLVSAGGLMIDAVREHGTTLLPVDSEHNAIFQCFPHHNRDYVRRIIITASGGPFRTTSLAEMATVTPERAVQHPNWSMGAKISIDSATMMNKGLELIEAYHLFQIPLEKFEILVHPQSVIHSMVEYLDGSILAQIGSPDMRTPIGHTLAWPKRMETPAESLDFTKLRQMDFEAPDYERFPALTLAMESIKSGGARPAVMNAANEIAVAAFLDKKIGFLDIAKIVEKTLDHYTPATPSSLEDVFAIDNEARIQAAALMESLPA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).  Cannot use NADH instead of NADPH as the reducing agent.
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: Y058_CHRSD
Sequence: MQSLKHHFLLAMPHLDDPNFKGTLTYLCDHDENGTMGVIVNRPMELTLDALLEQLELDAAECPCREMPVHYGGPVHKDRGFILHRGSSLPWDSSLQVADDIALTTSMDMLKAIANGQGPEDFIVCLGCAAWQAGQLEDELKQNTWLTVEGDASILFEVHAEQRLSAAAGILGIDLNLMSREAGHS
What are the official names of this protein?
UPF0301 protein Csal_0058.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RNHI1_THEGA
Sequence: DADIAVWAPPVNAQN
What is the function of this protein?
Has ribonuclease activity towards yeast tRNA and polyuracil, and decreasing ribonuclease activity towards polyadenine, polycytosine and polyguanine respectively.  Lacks antifungal activity against M. arachidicola and P. piricola.  Inhibits HIV-1 reverse transcriptase.
What are the official names of this protein?
Ribonuclease.
Protein: LISC1_POPTR
Sequence: MIEQSLSKPSFSLSIPIPQPPKSKSSFLCSYSKIRCESVDYPSSSKIDAKHPQISSINSNGGGKMGSYTGRDPNVKKPEWLRQKAPQGERYDEVKESLSRLKLNTVCQEAQCPNIGECWNGGGDGIATATIMVLGDTCTRGCRFCAVKTSRNPPPPDPMEPLNTALAIASWGVDYIVITSVDRDDLPDGGSGHFAQTVRAMKELKPEIMVECLTSDFRGDLKAVDTLVHSGLDVFAHNVETVKRLQRIVRDPRAGYEQSLSVLKHAKISKKGMITKTSIMLGLGESDNEVKEAMADLRAIGVDILTFGQYLQPTPLHLTVKEYVTPEKFAFWKEYGESIGFRYVASGPLVRSSYRAGELFVKTMVKESVKEAAAIS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 1, chloroplastic, Lipoate synthase 1, LS 1, Lip-syn 1, Lipoate synthase, plastidial 1, LIP1p 1, Lipoic acid synthase 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPD_ACET2
Sequence: MQLVNTRYAEALIDVTEEKNSTDKVLNNLVQVLKLLEENREFYSFLLDPQIQKESRKEAIIKVFEGRIEQEVVNFLMLLVDKERFENIRGIVEEYFRLADERKNILNMTIISAFPLEDVQINRIKEKYKKLYNKTDVKAKLIIDKSLIGGVKIQIGDKVIDDSIKGRLLCLKEALLQR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CLPX_STAAM
Sequence: MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YDA6_SCHPO
Sequence: MNNDNLHDKLTIWRQQQIELKGMLQLIPKFQSLNEIRYVVGLDISFDKSSPKAVSALVIYDLEQRMIIYKDYLCIEKLEEDYVPGFLSFREIKWYLPLLNHIPHQFRIDIILVDGNGVLHPVGFGLACHLGVLLNLPVVGVAKNYLHCVGLTESLDAHRETLKKHVLKKTTDHPILIHSIDQSSEILGAAVWTSSNSKRPVYVSIGNQMNLEQSIQLVQKCSSSHSRVPEPIRQADIYAKFVLSQSKRNKKN
What are the official names of this protein?
Putative endonuclease C1F12.06c.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMM_BACAA
Sequence: MTKWFNVGKIVNTHGVKGEIRVVSRTDFPEERYKVGNTLYISNEKGGEPFPVKITSHRQHKTFDLLTFEGYGNVNEVEQFKGSLLKVPEDQLGELAEGEYYYHEIIGCNVVTEEGEALGTIKEVLSPGANDVWVIKRPKGQDLLIPYIDDVVLQVNIENKLVTIHVTEGLL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJD_ECOLI
Sequence: MIDKIKSNARDLRRNLTLQERKLWRYLRSRRFSDFKFRRQHPVGSYILDFACCSARVVVELDGGQHDLAVAYDSRRTSWLESQGWTVLRFWNNEIDCNEETVLENILQELNRRSPSP
What are the official names of this protein?
Uncharacterized protein YcjD.
What is the protein family that this protein belongs to?
To H.influenzae HI_1162 and to HI_0925.
Protein: RPOZ_PASMU
Sequence: MARVTVQGAVEKIGNRFDLILTAARRARQLQLHIREPLVPEDNDKPTVIALREIEKGLINNEIMNAQERYDALEKENSELHAVSLLSNQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NADA_LISMO
Sequence: MNLLETVEQDTMPTHYKQMTQVEMIARVTEIKAQLGENLFIPCHHYQKDEVVPFADAIGDSLQLAQIAAQNKKAKHIVFCGVHFMAETADMLTTSEQIVTLPDMRAGCSMADMADIHQLTNAWPKLQTLFGDTILPVTYINSTAAIKSFVGEHGGTTVTSSNATKIVSWALEQKERIFFLPDQHLGRNTAFELGIPLEHMAIWNPIKNELEYEGNLDDCKVILWKGYCSVHQHFTVKNIENIRKNHPNMRIIVHPECTHEVVSLADDSGSTKKIVTEINNAAPGTEWAVGTEANLVGRIIQENPDKKIVSLNPFMCPCMTMNRIDLPHLLWTLEAIQNGEKRNQIKVDEQTTKFALKALERMLQLS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_CHRSD
Sequence: MAMLGKRRPPRTANERVRRERGSATRRDDATADGLSIERLAHDGRGVARDPHGKTVFVDQALPGERVRVAVHRQRKRFDEAHVVERLATSPERATPPCAYYGRCGGCDLQHLDLEAQREHKRRTLDELFTRQGLTLPEIEVLAGEGLAYRRRARLGVKCDAEGTPHLGFRARGSEHLIDIDSCVVLEPVLSRLIAPLRACLVQLEAPRRVGHIELIATAEGACVVVRQLREVPGDEARWRRFAAEHDVTLAWRVGREAPTLRWLHAPRGEALHVTLVLDDTTLSLGCVPGDFLQINADVNARLVRTALAWLAPRGEERVLDLFAGVGNFTLALAPRVASITGIEGSPAMVERLADNARRAGLHQVGAQQSDLATQVPEVAAVDWVIMDPPRGGAEALCRALADSPVTTLLYVSCDPAALARDAARLVQGGYRIQRAALADMFPHTAHLESMLLLTRDTPRGRSTSVEREDHGQGP
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: I13R2_CANLF
Sequence: MAFIHLDVGFLYTLLVCTAFGSMLSNAEIKVNPPQDFEIVDPGYLGYLSLQWQPPLFPDNFKECTIEYELKYRNIDSENWKTIITKNLHYKDGFDLNKGIEAKINTLLPAQCTNGSEVRSSWAETTYWTSPQGNRETKIQDMDCVYYNWQYLVCSWKPGMGVHFDTNYQLFYWYEGLDHSAECTDYIKVNGKNMGCRFPYLESSDYKDFYICVNGSSESQPIRPSYFIFQLQNIVKPMPPDYLSLTVKNSEEINLKWNMPKGPIPAKCFIYEIEFTEDGTTWVTTTVENEIQITRTSNESQKLCFLVRSKVNIYCSDDGIWSEWSDEQCWKGDIWKETLVFFLIPFAFVSIFVLVITCLLLYKQRALLKTIFHTKKEVFSHQDTFC
What is the function of this protein?
Binds as a monomer with high affinity to interleukin-13 (IL13).
What are the official names of this protein?
Interleukin-13 receptor subunit alpha-2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, IL-13RA2.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS8_RHOE4
Sequence: MTMTDPIADFLTRLRNANTAYHDEVKLPHSKIKANIAEILKREGYISDFRTEDAEVGKTLIVDLKYGPSRERSLAGVRRVSKPGLRVYAKSTNLPKVLGGLGVAIISTSSGLLTDRQAANQGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RK23_PELHO
Sequence: MDGIKYAVVTDKSLRLVSKNQYTFNVESGSTRTEIKSWVELFFGVKVIAMNSHRLPGKRRRMGHTMHYRRMIITLQPGYSIPSLINLII
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHAA_AGLNE
Sequence: MSIVTKSIVNADAEARYLSPGELDRIKSFVLSGQRRLNIAQILTDNRENIVKQGGQQLFQKRTDIVSPGGNAYGEEMTATCLRDLDYYLRLVTYGIVAGDVTPIEEIGLVGVKEMYNSLGTPISGVAEGVRCMKAIACSLLSGEDSAEAGFYFDYTLGAMQ
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the core of the phycobilisome.
Protein: SBP1_BOVIN
Sequence: MATKCGKCGPGYPSPLEAMKGPREELVYLPCIYRNTGTEAPDYLATVDVNPKSPQYSQVIHRLPMPNLKDELHHSGWNTCSSCFGDSTKSRTKLLLPSLISSRVYVVDVATEPRAPKLHKVVEPEEIHAKCDLSYLHTSHCLASGEVMISALGDPRGNGKGGFVLLDGETFEVKGTWEQPGGAAPMGYDFWYQPRHNVMISTEWAAPNVLRDGFNPADVEAGLYGQHLYVWDWQRHERVQTLTLQDGLIPLEIRFLHNPAADQGFVGCALGSNIQRFYKNQGGTWSVEKVIQVPPKKVKGWILPEMPSLITDILLSLDDRFLYFSNWLHGDLRQYDISDPKRPRLVGQIFLGGSIVKGGPVQVLEDQELKCQPEPLVVKGKRVAGGPQMIQLSLDGTRLYVTTSLYSAWDKQFYPDLIREGSVMLQIDVDTVRGGLKLNPNFLVDFGKEPLGPALAHELRYPGGDCSSDIWL
What is the function of this protein?
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (By similarity).  Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm.  May be involved in intra-Golgi protein transport.
What are the official names of this protein?
Methanethiol oxidase, MTO, 56 kDa selenium-binding protein, SBP56, SP56, Selenium-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the selenium-binding protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity).
Protein: CYB_CORCU
Sequence: MAPNLRKSHPLLKMVNNSLIDLPTPPNISAWWNFGSLLGICLVTQILTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASLFFICIYLHIGRGFYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAFPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYFSLKDFLGFALMLFLLTALALFTPTLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLLLVPFLHKSKQRTMTFRPLSQTLFWILVSNLFILTWIGSQPVEDPFITIGQLASITYFTIILILFPIISSLENKILNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PLSC_COCNU
Sequence: MDASGASSFLRGRCLESCFKASFGMSQPKDAAGQPSRRPADADDFVDDDRWITVILSVVRIAACFLSMMVTTIVWNMIMLILLPWPYARIRQGNLYGHVTGRMLMWILGNPITIEGSEFSNTRAIYICNHASLVDIFLIMWLIPKGTVTIAKKEIIWYPLFGQLYVLANHQRIDRSNPSAAIESIKEVARAVVKKNLSLIIFPEGTRSKTGRLLPFKKGFIHIALQTRLPIVPMVLTGTHLAWRKNSLRVRPAPITVKYFSPIKTDDWEEEKINHYVEMIHALYVDHLPESQKPLVSKGRDASGRSNS
What is the function of this protein?
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.  This enzyme shows a preference for medium-chain-length fatty acyl-coenzyme a substrates.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-AGP acyltransferase, 1-AGPAT, Lysophosphatidic acid acyltransferase, LPAAT.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: INX3_DROME
Sequence: MAVFGMVSAVSGFIKIRYLLDKAVIDNMVFRCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIPMHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQEKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNMEDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTRETIIKRSYRSAQRKEIAGLVRRLEIGDFLILHFLSQNLSTRSYSDMLQQLCGLLGASRTPSAPSTLEMNRISHPIYPPVETFGGGKETET
What is the function of this protein?
Structural components of the gap junctions.  Essential for proper epithelial development of the epidermis.
What are the official names of this protein?
Innexin inx3, Innexin-3.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Cytoplasm. Lateral cell membrane. Apicolateral cell membrane. Note=In ovary, localizes to the lateral membrane of follicle cells covering the oocyte and to the apicolateral membrane of follicle cells covering the nurse cells. In nurse cells, localizes to the membrane and around the nuclei.
Protein: J_SPV4
Sequence: MRRKVKNTKRHQWRLTHSARSIKRANIMPSNPRGGRRF
What is the function of this protein?
Mediates ssDNA packaging into virion, it locates to the internal surface of the capsid, thereby displacing the internal scaffolding protein during virion formation.  Additionally, protein ORF8 plays a role in viral attachment to the host cell (By similarity).
What are the official names of this protein?
DNA binding protein ORF8.
What is the protein family that this protein belongs to?
Belongs to the microviridae J protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CH10_BURVI
Sequence: MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGALIALDVKVGDRVLFGKYAGQTVKVDGQELLVMREEDIMAVVNAK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC1B_CAEEL
Sequence: MRQGGGGGERMVSVLFLLLIHLALCQAKCVMTECDGEEDSNHPPCKTNKSTYLPITVTRSLNPTYMARFEKYCSYLVQEEDKAQVCCTELQLKGMTDRISNAATILGSCPSCFDNFAKLWCQFTCSPDQSKFMKVMETTGPKNVVVKMEFKVNRDFVEGLYESCRHTWFANGLALRLMSLGGKVSFENFYGFMGTKNLAQSIPINTEFQFSRMKNAMNIPTTPCHKSAGPKVPACGAIDCPTNAHQLVDISKVEHLGTKVFHPHFPDFEWLLKICGCLALTVLLVFILKYSCHRRSAPNGEDGCYVDLGKGNLEVQFEGLCARYANAVIKHPLIFVSLGLIVAAACCSGNFKFHSLTHSVDQVSAADGETRRNEKKFIHSFGPNHRIEQIFINLPPTTKSMFNMPLFEEMFQLVGNIQNLTACYGNSSVKLDDICYKPIGKNHGCAIMSPTNYFQNKWTNFENAGPPTIDDEIFDDQHWEHLKYCIRNPLTVSTYSEMSCFGEFSGPIDPILVFGGSNESIKGAEMYYTARTIMITVLIRGPEDQAIAWETAFLNMMSRYEMKHANFTFMTETSVAEEIHTAVETDKIVSVIACAAVLIWVITMLGINHWPESSILSALVHHKLLISISAVMISVISVWCSIGMFSLFGVHATDNAIVVLFFVITCLGINRIFVIIRTFQANGHCYGLPNISYREMNHRISNVMRRSIPIVLTNSLICSTCLFLAGGVLPYVSVSMPAVEVFARHAGLAILMDTAFYLLVMLPLFQYDARREMSGKCEIWPWYELSNESKINLCMEAVDGNLRSPVDWFKLAIAPLLLKKICRIWIATFFFVSLIIACYCTLCLEFGFNQVMAFSETSYLTKHFQNMNENLNIGPPLWFVVEGDVKWHDPKMQNKFCTLAGCDDNSMGNKIRSLAYAENYKGNYLHGDVNIWLDSYLQFMHPRGSCCKMDGKQFCDPSNATHCSSCSSSSVASLTTTEYEFYRNLHHFLETPPSIQCAHGGMALAKPAINLTRNGKIQSAYFSTFFKKLNLSDSIQLYDAWRFAKYLADDIERELEIPGVKVYVYSTFFPYYEQYLTLSTTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLLSSYLHLMEWMYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERAFAALVSNGSTTLSGIFPAIMITAGCLSFADSRVLITYFCNQLVGIGLVCAVHGVVYMPTLLAIFGSDFYQNVSSEEESTDEAELQDTPPSTTSSTSSTSETSV
What is the function of this protein?
Involved in the uptake or utilization of cholesterol (By similarity).  Ncr-1 and ncr-2 act redundantly to prevent dauer larva formation under favorable growth conditions, and are required for the normal functioning of ADF, ASI and ASG neurons (PubMed:10801441).
What are the official names of this protein?
NPC intracellular cholesterol transporter 1 homolog 2, Niemann-Pick C1 protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DESI2_RAT
Sequence: MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNAAELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASTAMASAAAGGRTGRHTKL
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
What are the official names of this protein?
Deubiquitinase DESI2, Desumoylating isopeptidase 2, DeSI-2, PPPDE peptidase domain-containing protein 1, Protein FAM152A.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_PROM9
Sequence: MAKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLIQRIGITQLHASALEKIIDKSWQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQTDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQFANIIPVTNRAAKLGDIAVVSFKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHEDSRGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIKIEALLDALTNELVAEIPKSMIDIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTRPQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAISQSSKQIDIKKLTEVISKDLLKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEKK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PLSX_RHOPT
Sequence: MPQKVRIALDAMGGDFGPSVVIPGAAISLGRHPDVEFLLYGDAKLIEKELAAHPALRKASRVVHTDVAVAMHDKPSVALRRGRYKSSMWQAIDAVKKTEADVTVSAGNTGALMAMARFCLRTLPGIDRPAIAATWPTMRGDSVVLDLGASIGGDAQHLKALAIMGAAMASVLFDLERPTVGLLNIGVEEIKGGEEIREAAELLRAMNSQRFDFIGFVEGDGIGKGAADVIVSEGFAGNIALKAAEGTARQLAEYLRAAMSRTWRSKIGYLFARDAFKALKDKMDPNKSNGGVFLGLNGIVVKSHGGTNAEGFAYAVDVGYDMVRYDLLTKINQTLNRDAGALVATPSAQEVVS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SYE1_COXB2
Sequence: MMKSRFCPSPTGLMHLGNARTALFNYLFAKSKDGIFLLRIEDTDVERSKETFDLGLQEDLRWLNLEWQEGPGADEGNGPYHQSKRQAIYDDYYQRLEEADQAYPCFCSEEQLRLSRKIQRSAGKPPRYAGTCRSLSAAEIEKKKAEGLQPALRFRVPDDEVVVFADLVRGEQRFQTNDIGDFIIRRANGTSPFMFCNAIDDALMGVSHVLRGEDHLTNTPRQLLILQALELPVPTYAHIALIVGPDGSPLSKRHGSRGIKELRDNGYLPLALTNYLARLGHYYASDELLSLAELAKGFNVESLSKSPAKFNAQQLDYWQKQTVNQLPNDDFWEWAGSELQSQIPTDKADLFLTTVKPNVSFPRDVAYWVNVCFGKTFNLETAQSELLRATGNRYFEEAFEAFKKFGKDLNSVVSHLKEKLNLKGKPLYQPLRIALTGAEHGPELAKLILIMDYETIQNRLQEACQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_MESFL
Sequence: MYKIAFDVMGSDNGSAVAIEAASRFIKSRKDLYLVFVGDEDQIKTSLEKFPIDESRFEILATKEFIDMNGSIMDIRRKKDSSMVRALETLKDKKVDAMITGGNSAAFIAGSHFILGELNGISRPGFMPTLPTAVSNKLTLLLDVGANLEADIEDIIGYAKMANIYAKNVLKIENPLIAQLNIGEEKSKGTLLQKEIYKELESDENINFFGNLESRDILAGKVDIIVTDGYTGNMCLKAFEGASKILMTEIKSQLYKTIFTKLKALTLKKSFDNVSKKFDYKNHSGAILLGVEGIAFKAHGSSDVKSFEATLRMTCDAVENDVLNKIKKELN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.