PharMolix/UniProtQA huggingface dataset:
Protein: FTHS_CHLAA
Sequence: MKTSLQIAAEARLEPIAAIAERLGLPVRYLEPYGRYRGKIDLTFLDDYHDRPLGRYVLVSAITPTPLGEGKTTTAIGLAMALNRIGKRAAVTLRQSSLGPVFGIKGGGAGGGYSQIVPLVESILHLNGDIHAVSQAHNQLAALTDNSWYHGNPLDIDPDRIEIRRVVDVNDRFLRQVMIGLGGKQNGFPRQTGFDISVASELMAILAMVNGVGARAALRDLRSRIGRMVVAFRRDGTPITAEDVRGAGAATVLMREALKPNLMQTIENTPALIHAGPFANIAQGNSSILADLIALRCADYVVTEAGFGVDIGAEKFFNLKCRASGLWPDVAVIVATIRALKAHSGKYDIVAGKPLPPALLHENPDDVISGGANLRRQIENLHQFKVPVIVALNAYPEDTPAEIDAVAHIATTAGAAGMAVSNVYAAGSAGGVDLARLVIEIAERPGPRPVQFLYPLEWSLADKITTIAHRIYGAAAVTFSPTAAAQLAALEDAGFGNLPICMAKTHLSLSHDPALRGAPEGFTFPIREVRLSAGAGFILPIAGTTVTMPGLGAHPAAHQIDIDDEGNIVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RNAS1_PONPY
Sequence: MALEKSLVLLPLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSGSSPNSNSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTHGSRYPNCAYRTSTKERHIIVACEGSPYVPVHFDASVEDST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRC_GEOSM
Sequence: MNLLIKGGRVIDPSQGIDANLDVLIADGVVLELGQGLAAPEGTPAIDAGGLIVTPGLIDMHVHLRDPGLEYKEDIATGSRSAAAGGFTSVACMPNTSPVIDSKAIASYIINKAKSEALVNVFPIGCITKGGKGESLAEMGELKEAGCVGVSDDGKPVCNSELMRRALEYAKGIGITVISHSEDLALVGEGVMNEGFVSTELGLKGIPWAAEDIAVAREVYLAEFAGAPVHIAHISTVGSARIVRNAKARGVKVTCETAPHYFTLTDEAVRGYDTNAKMNPPLRSAADIEAMKAGLADGTIDAIATDHAPHHPDEKDVEFNVALNGIVGLETSLPLSLKLVEEGRLDLNQLVSLMSCNPAKILGLDRGTLKVGAVGDVTVIDPAKEWQVEAAKLESKSKNSPFLGWKMKGRAVYTVVKGQVVYQAG
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: ILVD_MYCA1
Sequence: MPTTDSARAADIKQPDIKPRSRDVTDGLEKAAARGMLRAVGMGDEDFAKPQIGVASSWNEITPCNLSLDRLAKAVKEGVFAAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLASVFLYAGSILPGVAKLSDGSEREVTIIDAFEAVGACARGLMPREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAIAHEADVALSLDDFSRIGSKVPHLADVKPFGRHVMTDVDHIGGVPVMMKALLDAGLLNGDCLTVTGATVAQNLAAIAPPDPDGKVLRALSDPLHPTGGITILRGSLAPEGAVVKSAGFDSDVFEGTARVFDGERAALDALEDGTITKGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVDAGPIAFLRDGDRIRLDVANRVLDVLVDPAEFDSRRTAFTPPPPRYKTGVLAKYVKLVGSAAIGAVCG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GAHP1_LACP7
Sequence: MSEKLTGRVTVPTDVDMIQETKEIAERWGADALRDCDGTDMPDELKKMPAKIYSTYYTTRKDNAWANANPDEVQQVYLMTEFYTAMSQGELRIPLMKHLYKDQLKPNTIHDIKRWWEVVDRTTGEPLVLDAWEYDENNQEVIILNPDHFHDYTVSFLAFIIWDPVHMYNFITNDWQDVEHQITYDVRQPKTQKYVIEKLKRWMKENPDSDVVRFTTFFHQFTLVFNEFAKEKFVDWFGYSASVSPYILEQFEKEVGYKFRPEYIIDQGYHNNTNRVPSKEFRDFQEFQQREVAKLMKVLVDICHDNDKEAMMFLGDHWIGTEPFGEYFKHVGLDAVVGSVGNGTTLRLISDIPGVKYTEGRFLPYFFPDVFHEGGDPIKEAKVNWVTARRAILRKPVDRIGYGGYLKLALDFPEFIQYIEEVCDEFRLLYDNMGGQSPYSHFKVGVLNSWGKIRSWGTHMVAHAIDYKQTYSYAGVLEALSGMPFDVEFISFEDVIKNPVILNECGVVINVGDAYTGPSGGAYWTNEKVSSAVKAFVAQGGGFIGVGEPSACEHQGRYFTLANVLGVNKEIGFSMSTDKYNWDEHSHFITEDSNESINFGEGMKNIYALDGAQILRKDGQDVQMAVNQFGDGRSVYISGIPYSFENSRMLYRAIFWAAGMEQEMKKWYSSNYNVEVNYYPATKKYCIVNNTYEPQETMIYDGLGREYSMKLKANDILWFTFLED
What is the function of this protein?
Reversibly phosphorolyzes beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine to form alpha-D-galactopyranose 1-phosphate and acetyl-D-glucosamine.  Active towards galacto-N-biose and lacto-N-biose.  Does not phosphorolyze galacto-N-tetraose or lacto-N-tetraose.  In the reverse reaction has activity toward N-acetyl-D-glucosamine and N-acetyl-D-galactosamine, but not L-rhamnose, D-glucose or D-galactose.
What are the official names of this protein?
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase Cphy3030, D-galactosyl-1,4-L-rhamnose phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycoside hydrolase 112 family.
Protein: CP1A1_MOUSE
Sequence: MPSMYGLPAFVSATELLLAVTVFCLGFWVVRATRTWVPKGLKTPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQKVMAEVGHFDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRKLDENANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPGEKVDMTPTYGLTLKHARCEHFQVQMRSSGPQHLQA
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions.  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation.  Catalyzes the epoxidation of double bonds of certain PUFA.  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system.  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer.  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: RLMN_SALPB
Sequence: MSEQIVTPESSTPVVLNNETKINLLDLNRQQMREFFKNLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDTIRDEIVPINKKYNIETFLGAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_STAA1
Sequence: MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQALLINIGTLTAQNEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFCKLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVAIAKKAYAIYKTAIVITGKEDVIVQDNKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVFNIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NANA_ECO57
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_MICLC
Sequence: MADPARAGRLAQRIKVLVAEALRRGVKDDRVEPVTVTEVRVTNDLQHATVYYTVLGDEATVAAAHEGIQDNRGILRREVGRGLTIRLVPTLEFVADTVPEAAAHLEDVLRAAKERDAELAKAREGASYAGDADPYRTAEPDADDAPRA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLAT2_MOUSE
Sequence: MEAQELGSPTPTYHLLPKANQHTVKEDAGSPSQGSPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQGHTEHFQDAFKGSSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFSYWFFVGLSVVGQLYLRWKEPDWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDTINSLIGIGIALSGVPVYFLGVYLPESRRPLFIRNVLATVTRVTQKLCFCVLTELDVTEEKNVERKTD
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids such as L-arginine from inside the cells in exchange with neutral amino acids like L-leucine, L-glutamine and isoleucine, plus sodium ions and may participate in nitric oxide synthesis (By similarity).  Also exchanges L-arginine with L-lysine in a sodium-independent manner (By similarity).  The transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (By similarity).  Contributes to ammonia-induced increase of L-arginine uptake in cerebral cortical astrocytes leading to ammonia-dependent increase of nitric oxide (NO) production via inducible nitric oxide synthase (iNOS) induction, and protein nitration (By similarity).  May mediate transport of ornithine in retinal pigment epithelial (RPE) cells (By similarity).  May also transport glycine betaine in a sodium dependent manner from the cumulus granulosa into the enclosed oocyte (PubMed:24599290).
What are the official names of this protein?
Y+L amino acid transporter 2, Solute carrier family 7 member 6, y(+)L-type amino acid transporter 2, Y+LAT2, y+LAT-2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: RL15_XANP2
Sequence: MNLEDIRDNPGARKKRMRVGRGIGSGKGKTAGRGVKGQKARTGVAIKGFEGGQMPLHRRLPKRGFHNIFRLDYNEVSLGKIQAAVEAGKLDAGQPVTEAALVAAGVLRRAKDGVRVLGTGELSAKVTLEVAYATKSAVAAVEKAGGSVTVLAAPAVAEAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: DPO3B_MYCPU
Sequence: MKLFLEKSRFLRFLENTTKIIESNNSNYELRGAYFQVRQDKIILISSNEDISIKNEYLLDGIKNKTEGESDFLVLNSLLKNIIKKCSDSIILEKEKNTLKIFSDLQSYEINLLDHERFPDIKFGLNNSQLQLKTEQFKQALKNVVFAADLSNAQELLLNSVNLSLKNNILTLVATNRARIAMQKIKTEDSQEFNLTINSKVVKELISLSMSNTLILSPGTFELKIKSGNLEIKTKVIEIPYMNVENVFPNKFNFVIHIDKKELLSLIDKVSIVNDEKNGNKILIEYNPSKKEKKLKLSSYWPDLGFSEVFSDNFEVESEILLKFFINANYLKESINVFDGMISIFITENKDRMVISSETNLNNKQLIAALRGH
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_HAEDU
Sequence: MTTYNLRLKAKDELTPHPSVQYWRKCQVEELFAMPFMELVFKAAQVHREHFDPQAIQLSTLLSIKTGGCPEECEYCPQSARYDTGLEKQVMLDIEEIVEKAKIAKQRGASRFCMGAAWRGPKPKDIKVVSEIIGAVKALGLETCGTFGLLEDGMAEDLKQAGLDYYNHNLDTDPERYSKVVHTRSHDDRMDTLGKVRHAGLKVCCGGIVGMNETRPERAGLIASLANLDPQPESVPINQLIKVEGTPMAEAEDLDWTEFVRTIAVARITMPKSYVRLSAGRTAMSEAMQTLCFIAGANSIFYGEKLLTTCNPEEDADCLLMQKLDLYPLQYQEC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ANKHB_DANRE
Sequence: MMKFPALTHYWPLIRFLVPLAITNIAIDLGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGTVAIVFHTLIAYTNLGYYIINKLHHVDESVGSKTRKAFLYLAAFPLLDAMAWTHAGILLKHKHSLLVGCASISDVVAQIVFVGILLHSHLECVEPMLIPILSLYMGALVRFTIVGLGYYKVIHDNIPESSGPEVGGDATIKKMLSFWWPLALILATQRISRPIVNLFVSRDLKGSTAATEAVAVLTATYPVGHMPYGWLTELRAVYPAFDKNNPSNKLINSGTVVTKSHIKRFTFFCLALSITLCFMVFWAPHISESILVDIIGVDHAFAELCITPLRIFSFFPIPVTIRAHLTGWLMTLKKTFVLAPSSVLRIIVLISSLIVLPYMGVHGATLGVGSLLAGFLGESTMVAIAACYVYRKQKKKKDSDEDMTIDGEDSAPMNEVRSRGRMDDIVELREEDEEELDED
What is the function of this protein?
Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
What are the official names of this protein?
Progressive ankylosis protein homolog B, ANK-B.
What is the protein family that this protein belongs to?
Belongs to the ANKH family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NFI_SALG2
Sequence: MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSTEPGALSPLMDKGEQLAWVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRWQEIQR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_STAAM
Sequence: MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANMQTVMNEKLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDFIEKLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTPEGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPLIADGGIRTHGDIAKSIRFGASMVMIGSLFAAHEESPGETVELDGKQYKEYFGSASEFQKGEHKNVEGKKMFVEHKGSLMDTLKEMQQDLQSSISYAGGKDLKSLRTVDYVIVRNSIFNGDRD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: SPB4_ASPCL
Sequence: MAPNPPKGTSSRAWDAVTPPLSEWVLEAMSSMGFARMTPVQASAIPLFMAHKDVVVEAVTGSGKTLSFLLPIVEKLLRLEEPIKKHHIGAIIISPTRELASQIHSVMQSLLAFHPPSAAAMTPLDDDDAPRQKFPSSTLKVVPQLLLGGSTTPAEDLSRFLKLSPNVLVSTPGRLLELLSSPHVHCPQSSFEMLVLDEADRLLDLGFKETLQNILRRLPKQRRTGLFSASVSEAVDQIVRVGLRNPVKIMVKVKGTSGVDDKRTPASLQMTYLSTPPLHKFAALKNILSSVQPTPQKSIFFVSTCSGVDYLSAILPLLLGDDFLLIPLHGKHQANVRQKNFNRFLSSHSPAILLTTDVASRGLDIPSVDLVVQIDPPSDPKTFIHRCGRAGRAGRRGLSVVMLHPGREEDYVSFLDVRKTPVVPFSPSISFSDADATSATARARKAVLADRALHDRGQKAFVSWLRSYSKHQASSIFRVADLDWEALGKAWGLLKLPKMPELRSFTGDKTLGVSLDWDNFSYKDKQREKRRKELLQEAAESGVSQPSSNKRRASESVAWSQNAENKNKKLQRREYKKLKQEKTKWENMTEEERQKARETKEMVEELRAKNLEERRFRQAAAKAETAKAGGEDEEFKGFD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase spb4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TIG_MAGSA
Sequence: MQVTEINAEGLKREFKVVVPAQQLETRMQDKLAEIARTVAMPGFRPGKVPMTIVRKKYGGAVMGEILENAVNDGAGKAITDGGLRPAMQPKIEITKYEENSDLEFTVAVEVLPEIKTMDFGTINLVRDKAVVPDAEVDDALAKIAERNETSEPVKRASKSGDVVVIDFVGKVDGVAFPGGTAEGYSLKLGSNTFIPGFEDQLVGKKAESDVEVNVTFPEGYGNETLAGKPALFEVKVKEVRAPKAAAVDDELAKSVGLENLDALKTAIRDEISRELDGVSRMKLKRALLDALSDGHDFPVPPSMLEGEFEAIWKQVEADKEAGRQDPADAAKSEDELKADYRALAERRVRLGLLLADVGRVNEINVTQEDLNRGIMMEARRYPGQEHLVLQYYQKNQEALESLRAPLYEEKVVDFILELAKITDKEVSVEDLRKDPDEASADGEAAPAKPKKKAAAKKKAAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ALLS_DROME
Sequence: MNSLHAHLLLLAVCCVGYIASSPVIGQDQRSGDSDADVLLAADEMADNGGDNIDKRVERYAFGLGRRAYMYTNGGPGMKRLPVYNFGLGKRSRPYSFGLGKRSDYDYDQDNEIDYRVPPANYLAAERAVRPGRQNKRTTRPQPFNFGLGRR
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Allatostatin-A, Allatostatins Ast.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS4_ACIET
Sequence: MLLIPAIDLKDGHCVRLKQGDMDQSTTFGEDPAAMARKWADAGARRLHLVDLNGAFAGQPKNKAAIKAILAEVGADIPVQLGGGIRDLDTIERYIDAGLRYVIIGTAAVKNPGFLKDACSAFGGHIIVGLDAKDGKVATDGWSKLTGHEVVDLARKFQDWGVESIIYTDIGRDGMLSGINIEATVKLAQALTIPVIASGGLAGIADIEKLCEVENEGVEGVICGRAIYSGDLDFAAAQHRADELSLA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNPEP_ASPOR
Sequence: MTSKIAQNLKQPALDFLSFVNASPTPFHAVQSAKELLSKAGFQEIKEKDSWSSTCRPGGKYYLTRNSSTIVAFAIGKKWKPGNPISMIGAHTDSPVLRIKPVSNKRGEGFVQVGVETYGGGIWHTWFDRDLGVAGRAMVRTGDGSIVQKLVKIDRPILRIPTLAIHLDRQETFAFNKETQLFPIAGLVAAELNRTADSTATGEKTAANNETEKGDFAPLKSVTERHHPYLVELIAAEAGVKPDDILDFEMILFDTQKSCLGGLLEEFVFSPRLDNLNSSFCATVGLIDSVADASALDDEPSIRLIALFDHEEIGSRTAQGADSNVLPAIIRRLSVLPSSTSGNEDLATAFEETLSTSFLLSADMAHAVHPNYAAKYENDHRPEINKGPVIKINANARYATNSPGIVLLQEVARKAAEDGGEGVPLQLFVVRNDSSCGSTIGPMLSAALGARTLDLGNPQLSMHSIRETGGTYDVGHSIRLFTSFFKHYSNTSKTIFVD
What are the official names of this protein?
Aspartyl aminopeptidase, DAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: AGALA_ASPFU
Sequence: MDTTKSLLSTLIAIMIPLSLGSVSSPNLLPTPPMGFNNWARFMCDLNETLFLETASAMISTGLLEAGYNRVNLDDCWMAYDRAADSSLQWNTTKFPHGIPWLARHLKAQGFHVGIYEDAGNLTCGGYPGSFGHEALDAQTFAAWGIDYLKLDGCNVFPEHSRTLEEEYKARYAHWHSILKQMHHPLIFSESAPAYFADPANLTSWYEVMDWVPAFGELARHSTDILVYVGEGSAWDSIMVNYRYNTLLARYQRPGYINDPDFLIPDHPGLTLEEKRSQFALWASFSAPLIVSAYIPGLSSEELAILRNEELIRVDQDVLGLQATLASRGLEVDVLTRSLEGGDRLLTVLNRGDGVAVVSVPVEWMGLQRGCPYVVKNLWDGEVQVLEEEIVIRLNSHATQVYRIALPDECSTVIPTGIVFNTASGNCLTDENGERVGFEACRGSETQIWQVSELGYLRPLSRTSHCLTGGSQASVQLCTEQKNQQWAYAITGILKNEHTEMCLTEGTGISQCGFERDSQVFGLPSGVDIKPS
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
What are the official names of this protein?
Probable alpha-galactosidase A, Melibiase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UC30_MAIZE
Sequence: SGTSPLLPAITFILD
What are the official names of this protein?
Unknown protein from spot 662 of 2D-PAGE of etiolated coleoptile.
Protein: Y1470_BACVZ
Sequence: MASEIIVDHQQKAFELLKLDAEKILKLIRVQMDNLTMPQCPLYEEVLDTQMFGLSREIDFAVRLGLVDENDGKELLDRLERELSALHDAFTGK
What are the official names of this protein?
UPF0358 protein RBAM_014700.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.