PharMolix/UniProtQA huggingface dataset:
Protein: DRDI_LACP7
Sequence: MENVTLSPDGKSVVIIDQTKLPNAIEYLTLSTSRQMYDAIFALKVRGAPAIGICAGFSIYCLAQTIEETEYDAFLLKFREYKDYLDSSRPTAVNLSWALKRMGKVVLDAKDKSIDEILSLLKAECIAIKEEDIKICKAISEYGLEFLKDGDGILTHCNAGPLATSQYGTALGPLILGKERGMNFKVFADETRPLLQGARLTAFELHEAGIDVTLICDNMASIVMKNGFINACFVGCDRVAENGDTANKIGTSGVAILAKHYGIPFYVMCPTSTIDLNCKTGDDIEIELRSEDEIKSKWYEKPMAPSDVKCYNPAFDVTDHNLITAIITEHGVCKAPFEVSLREAVKKAEDIINK
What is the function of this protein?
Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
What are the official names of this protein?
5-deoxyribose 1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.
Protein: ARP6_MOUSE
Sequence: MTTLVLDNGAYNAKIGYSHDSVSVIPNCQFRSKTARLKTFTANQIDEIKDPSGLFYILPFQKGYLVNWDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYFNFTSIQESMNEILFEEYQFQAVLRVNAGALSAHRYFRDNPSELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEDNTVMIDYVLPDFSTIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQPHFFKNIVLTGGNSLFPGFRERVYSEVRCLTPTDYDVSVVLPENPITYSWEGGKLISENDDFEDMVVTREDYEENGHSVCEEKFDI
What is the function of this protein?
Required for formation and/or maintenance of proper nucleolar structure and function (By similarity).  Plays a dual role in the regulation of ribosomal DNA (rDNA) transcription (By similarity).  In the presence of high glucose, maintains active rDNA transcription through H2A. Z deposition and under glucose starvation, is required for the repression of rDNA transcription, and this function may be independent of H2A. Z (By similarity).
What are the official names of this protein?
Actin-related protein 6, mArp6.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Nucleus, nucleolus. Note=Colocalizes with HP1 family proteins at pericentric heterochromatin.
Protein: PROA_PECAS
Sequence: MLEQMGKAAKAASYQLAVLNTAQKDRALLTIADLLEVESATILAANVLDLADARQNGMSEALLDRLLLTQERLSAIASDVRQVCRLTDPVGQVIDGSMLDNGLKLERRRVPLGVVGVIYEARPNVTIDVASLCLKTGNAVILRGGKETYRTNAATVKVIQQALSQCDLPAAAVQAIESPDRELVNQLLKLDRYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYADDSIDFDKALTVIESAKVQRPSACNSLETLLVNRSIADRFLPELSKKMAASGVTLHASSLAMPYLTSGPANVVAVEDANYNDEWLSNDLNVTLVDDLDAAVAHIREHGTQHSDAILTRSLSNAERFVREVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGYGDDLIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ACICJ
Sequence: MDNRRLLYSISISLVILVLFQVIASYVLPPPKKAPPHPATQTAQTQPVSGQPAPGVPAPSAVPPAAAPGGVAAKIPAGPRLAISTPLLRGSMSLVGARLDDLVLTRYHQTVKKTSPLVQLLSQAGTAKSYYVQFGWDAAPGSSLKVPGPDTVWTSSGGDLSPAHPVTLSWNNGAGVTFELKLAVDRQYLFTVQQRVINHGAAAVEVYPWSRIRRDFLPEEPGSFTLHKGPIGVFHGTLHEMGYEGVKSGGKHPAAGDAPGTAYQTTNLGGWAGITGKYWLTALIPSQGREVIGAYRYLADPGQPEHGGYQVDYMTAKPVDAAPGATASTTTHVFAGAKVLSILSHYETQYRIPLFERAIDFGWFFFLTKPIFIALDYLAGVFGNMGVAIIVFTIGLKLVLFPLVRTSYRSMARMRAITPKVQALRERYKDDQMQQQKEIMALYKAEGVNPAAGCLPMLPQIPIFFSLYKVIFISIGMRHAPFVLWIHDLSAEDPTNIFNLFGLLPFHPSALSPFLHLGILPIIMGITMWGQQRLNPPPPDPTQAKMMQFMPVIFTFMLGRFAAGLVLYYCVNNTLTILQQWTIMRGTNAAPRAAANLNAKG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_MYCS2
Sequence: MMLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTPSMGGVAILAGIWAGYLGSHLVGMAMGGDGPSASGLLVLGLATVLGGVGFIDDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGDGLTPGSAELSYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTAAYVLITFWQYRNACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNAAPAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFYGEWLTAVGA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_ECO8A
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: FAU1_AERPE
Sequence: MLYAVRVRGIYATALVALALKKGYLLSDLSKTMLSRVEVPVSTRPPNITVKHGEESRDEIVIHAFPYEAGERFEADLLEEVGHAAVRRSLLGLRSVVDARAAEGCRAEGPGGVLIIVKGGECPQPGSMVRVTVVRSPPGSDVVEGRVGVELTGLTVRVMHPGSGVRISRHLTSEDAAKALKAVEASGIDLNQFSVHIRSGARLASEGDISDEIRRLAREAERLWREGPGGEPAVLSRGEYLSLVYLPSTAKHVMDGLRTSLYPTVNNHHSLKSWSSEAEGLLTDFAEEGVREGLWGGEAGDLIVRFISSRLVGRTAVVLHRRPDGETIRLGPFRVSSYRPSSGRGGEIVLERTFRSPGVYDGLGLERRPGDRGVTHVYMGDWLTIHEYYDKSGRLLGVYANINTPPEVGFQGLKYLDLLVDVVKRPGEEPETIDQGELEKACRSGLLTDRLCEEAARQAERASGLLQSRYP
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: LHA2_RHOSU
Sequence: MNNAKMWLVVKPTVGIPLFLVACAIASFLVHLMLVLTTGWMGDYYSGSFEAASLVSNATTLLS
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/850 alpha chain, Antenna pigment protein alpha chain, LH-2.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: RK14_ADICA
Sequence: MIQIQSYLDVADNSGARKLMCIRVLGTGNRKYADIGDIIIAVVKEAVPNMFLKRSEVVRAVVVRTRRGLKRRNGMVLEFDDNAAVIINQEGNPRGTRIFGPVARELRECNFARVVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YJM0_YEAST
Sequence: MTFATQVGEVRSKDTGSYNWFDHFFLCVYLALGISKWPSCMKLYRVCFIFLFTGGFFLFWLSYNRDHERSSSLRIKKVPIHIQKSDYFPSSTWIAVLVFSWRHIFCF
What are the official names of this protein?
Putative uncharacterized protein YJL120W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MPAC2_CARBE
Sequence: MGVFNYEAETTSVIPAARLFKAFILDGNKLIPKVSPQAVSSVENVEGNGGPGTIKKITFSEGSPVKYVKERVEEIDHTNFKYNYTVIEGDVLGDKLEKVSHELKIVAAPGGGSIVKISSKFHAKGYHEVNAEEMKGAKEMAEKLLRAVESYLLAHTAEYN
What are the official names of this protein?
Major pollen allergen Car b 1 isoform 2, Allergen Car b I.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: NADC_BACSU
Sequence: MNHLQLKKLLNHFFLEDIGTGDLTSQSIFGEQSCEAEIVAKSEGIFAGAAIIKEGFSLLDENVQSILHKKDGDMLHKGEVIAELHGPAAALLSGERVVLNLIQRLSGIATMTREAVRCLDDEQIKICDTRKTTPGLRMLEKYAVRAGGGYNHRFGLYDGIMIKDNHIAACGSILEACKKARQAAGHMVNIEVEIETEEQLREAIAAGADVIMFDNCPPDTVRHFAKLTPANIKTEASGGITLESLPAFKGTGVNYISLGFLTHSVKSLDISMDVTLSNESVEECCYVNS
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], General stress protein 70, GSP70, Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: K1C23_MOUSE
Sequence: MNSSHSFNQTYSASVHSLGSTRGRQGSCHRAPSVHGGAGGVRISLSFTTPGCLPPGGSWGSGRSSPLLGGNGKATMQNLNDRLATYLEKVRALEEANSKLETRILRWHQEREPSHRKDYSQYEENISRLQEQIVDGKMANAHIVVLIDNARMAVDDFNLKFENEHSLKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEMEENHLPSDFKVSVKVDTTPGEDLIKVLEDMRQEYELIIKKKHQELDTWFREQSAAMAQEVASPAPVQGNQSDIHELRRTFQALEIDLQAQHSRKTALENMLTETRARYSCRLQDMQQIISHYEEELIQLRQDLERQNNEHKVLLGIKTHLEKEIATYRRLLEGDTEGTMDGSESRLKGSEASTIKAITQESVNGRIVLSQVNEIQKHI
What are the official names of this protein?
Keratin, type I cytoskeletal 23, Cytokeratin-23, CK-23, Keratin-23, K23.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: THIC_NOVAD
Sequence: MADINSKLEIGVTTGPIRGSRKIHVESARFPGLTVAMREIQLEPSSGEPPVRVYDTSGPYTDPKVTIDIAAGLPTLRRDWIMARGDVEEYDAREVKPEDNGLKGPDRSAGVPPFPNVVKRPLRAKAGQNVSQMHYARRGIITPEMEYVAIRENLGRKQAKEAMIRDGQDWGASIPDYVTPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVASEVDKMVWSIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVGGVAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVRLPYIPLAAKRMTGIVSRGGSIMAKWCLAHHKESFLYENFDEITEIMKAYDVAYSLGDGLRPGSIYDANDEAQFAELYTLGELTKRAWEQDVQVMIEGPGHVPMHKIKENMTKQLEACGEAPFYTLGPLVTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAQARDDALSKARFEFRWRDQFNLSLDPETAEQYHDQTLPAEGAKTAHFCSMCGPKFCSMKISQEVRDFAAKQNAGIETFVANEAEAEAGMKAMSDKYDEMGRELYIGAGGREHD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HPRT_MUSSP
Sequence: MATRSPSVVISDDEPGYDLDLFCIPNHYVEDLEKVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKQYSPKMVKVASLLVKRTSRSVGYRPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase, HPRT A.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_PSEP1
Sequence: MAKQKKHPTGTIAQNKKARHDYFIEHKFEAGLVLSGWEVKSLRAGKAHLTDSYVLLKDGEAWLFGSHITPLTTASTHVIADPTRTRKLLLNKRELERVEAAVAQKGYTCVALALYWSKHLIKCEIALGKGKKEFDKRDTMRERDSNRELQRAVRNKGKEE
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DDL_RICCK
Sequence: MHQYQIHWVEHSEVKILSNIVVRLEYKERGVKSITNRRARHDAVSESKSIDYSGKKHIALVAGGMSAEREVSLVSSKGVSKALIALGYKVTFIDMGADIAFKLQEIKPDIVFNCLHGTYGEDGCLSGLLNIMRIPYTHSGVLSSALAFDKIYSRSWFLTNNINMAESIVVNKSDNIKIEPMKRPYVIKPITQGSSIGIEVIFEEDDFNFANYDFPYGDQVIIEKYIKGRELQVAVLNGKALGVLEIKLLKNRFYDYETKYTEGFAEHLCPAPIPTNLYDKLLIESEKIYKTMNCKGPARVEFLLEDQTNKLYALEINTHPGMTPLSIVPEIAAYAGINFTNLIEEIIKAASFES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B5_ORYSI
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKAPAGKKPKAEKRLPAGKGEKGSGEGKKDRAGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAAEAAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.5.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GR36C_DROME
Sequence: MDLESFLLGAVYYYGLFIGLSNFEFDWNTGRVFTKKWSTLYAIALDSCIFALYIYHWTGNTNIVNAIFGRANMLHEYVVAILTGLRIVTGLFTLILRWYQRCKMMDLASKVVRMYVARPQVRRMSRWGILTKFIFGSITDGLQMAMVLSAMGSVDSQFYLGLGLQYWMFVILNMAMMQQHMIMLFVRTQFQLINTELRQVIDEAKDLLLSPRHQGVFMTKCCSLADQIENIARIQSQLQTIMNQMEEVFGIQGAMTYGGYYLSSVGTCYLAYSILKHGYENLSMTLSTVILAYSWCFFYYLDGMLNLSVMLHVQDDYWEMLQILGKRTIFVGLDVRLEEAFENLNLQLIRNPLKITVVKLYDVTRSNTMAMFGNLITHSIFLIQYDIEHF
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 36c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS2_LACLA
Sequence: MNKKILQILEYDKVKEQFMNALTTAQGQQELKDLKPLTDKEKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLELEASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLAITLEKLVDLSALVKKLEIFDNAGSLYDNASLELMHIRASIKSHQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEERQEITRIYRELASQLKPYSFDIRQNAWLIGHIDFVRAKYLYLAANKATLPELTTDKDITLFAARHPLIEAKIVVTNDIKFDAGLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILAADGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVHILAQADENSLVLFDELGAGTDPKEGAALAIAILENLRERNVKTMASTHYPELKAYGVETQRVINASMEFNIDKMQPTYHLQLGVPGRSNALEISRRLGLPETIISVASQQISDSEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINREREFELEKAQKEAQEVVKKASLEAQEILKNLNDKAALKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVTSYGQRGKLIRLEKDGRWTVQMGSITTRLNEDEFEVIESPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYIDQALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: ISPE_SULDN
Sequence: MKMKLYRAYAKVNIFLKIQGSRGNYHEIVSRFMRVPSLYDELSFVPKESSEEFELIGSFSCKREQNTIYKAYRALLEFLDEASGLHVENLMQKYAVKVTKNIPTFAGLGGGSSDAATFLKMCNEVLHLGLSQNELALIGLHVGADVPFFIYGYNSANVSGIGEVVEEFKEELLDIEVFTPQLEISTPKVYNLYRENFYNPVDGFEVERLKKISSKDALSAMSAAEANDLFAPAIQLYKELKNHYKYGYYFSGSGSSFFRVKEKENI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: DXR_STRCO
Sequence: MSDSPAPLADPHLVYDPVAGDGPKDVVVLGSTGSIGTQAIDLVLRNPDRFRVTALSANGGRVALLAEQAYRLKARTVAVAREDVVPALREALTAQYGTGEPLPEILAGPEAATQLAASDCHTVLNGITGSIGLAPTLAALEAGRTLALANKESLIVGGPLVKALAKPGQIIPVDSEHAALFQALAAGTRADVRKLVVTASGGPFRGRTRDELAAVTVEDALAHPTWAMGPVITINSATLVNKGLEVIEAHLLYDIPFDRIEVVVHPQSYVHSMVEYTDGSTLAHATPPDMGGPIAVGLGWPERVPDAAPAFDWSKASTWEFFPLDNEAFPSVDLARHVGQLAGTAPAVFNAANEECVEAFRSGALPFLGIMETVTRVVEEHGTPRTGTSLTVADVLEAETWARARARQLAAQTAEARA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: DNLJ_ECO5E
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTYCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: VPS55_YEAST
Sequence: MMEFKVSPLTKIISLSGFLALGFLLVILSCALFHNYYPLFDILIFLLAPIPNTIFNAGNKYHTSDFMSDSSNTGQDLAHFLTGMLVTSGIALPVVFYHCQLIGHLSCIMCMIGGLIIYSSIVIFKWFFKKDFNEDDSLFG
What is the function of this protein?
Involved in protein transport from endosomes to the vacuole.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 55.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: IF2B3_CHICK
Sequence: MNKLYIGNLGENVSPLDLESLFKDSKIPFSGQFLVKTGYAFVDCPDESWAMKAIEALSGKVELHGKLIEVEHSVPKRQRSRKLQIRNIPPHLQWEVLDSLLAQYGTVENCEQVNTDTETAVVNVTYGNKDQARQAIEKLNGFQLENYSLKVAYIPDEMAAQQPPQQHPQGRRGFGQRGPPRQGSPSATTRQKPQSDVPLRMLVPTQFVGAIIGKEGATIRNITKQTQSKIDIHRKENAGAAEKPITIHSTPEGCSTACKIIMEIMQKEAQDTKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQDLTLYNPERTITVKGSIETCAKAEEEIMKKIRESYENDIAAMNLQAHLIPGLNLNALGLFPPSSSGIPPPAVSVASAAAAASYPPFGQQPESETVHLFIPALAVGAIIGKQGQHIKQLSRFAGASIKIAPAEGPDAKLRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLEAHIKVPSYAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTPDENDQVVVKITGHFYACQLAQRKIQEILAQVRRQQQQQKTLQSGQPQPRRK
What is the function of this protein?
RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs).  This transcript 'caging' into mRNPs allows mRNA transport and transient storage.  It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation.  Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability.
What are the official names of this protein?
Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IMP-3, IGF-II mRNA-binding protein 3, VICKZ family member 3.
What is the protein family that this protein belongs to?
Belongs to the RRM IMP/VICKZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Cytoplasm, Stress granule.
Protein: K1C26_HUMAN
Sequence: MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGWYEKCEPGSSREHDHDYSRYFSVIEDLKRQIISATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP
What are the official names of this protein?
Keratin, type I cytoskeletal 26, Cytokeratin-26, CK-26, Keratin-25B, K25B, Keratin-26, K26, Type I inner root sheath-specific keratin-K25irs2.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.