PharMolix/UniProtQA huggingface dataset:
Protein: VP4_ROTBA
Sequence: MASLIYRQLLYNSYSVDLSDEITNIGAEKKENVTVQIGGFAQSQYAPVSWGSGETLSGNVEEQTLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSWTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFEDYIKTSPTQSYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSHPVPNAVINLNADFYVIPDSQQEICTEYIRGGLPAMQTTTYVTPISYAVRSQRVARPNEDIIISKASLWKEVQYNRDIVIRFVFANNIIKAGGLGYKWSEISYKANNYQYTYMRDGVEVVAHTTVSVNGVSVYNYNTGPLPTDFMIRNYDVLKESSFVYVDYWDDSQAFRNMVYVRSLNAELNQVRCVGGHYSFALPVGSWPVMQGGSVILTFDSVTLSTQFTDYVSLNSLRFRFRCAVSEPPFRVTGTRISNLYGLPAANPMGDQQYYEASGRFSLISLVPSNDDYQTPIANSVTVRQDLERQLDEMRREFNELSANIALSQLIDLALLPLDMFSMFSGIQSTVEAAKTFATSVMKKFRKSDLAKSVNSLTDAITDAAGSISRSSTLRSVNSVASVWTDISDIVDSTDNVVAATATAAAKKFRVKEFTTEFNGVSFDDISAAVVKTKMNKLNVVDEELLPQIITEASEKFIPNRAYRLIDGEKVYEVTTEGKYFAYLTETFEEVVFDAERFAELVTDSQVISAIIDFKTIKNLNDNYGITREQALNMLRSDPKVLRSFINQNNPIIKNRIEQLILQCRI
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: TRPD_SULIK
Sequence: MNINDILKKLINKSDLEIDEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNAIDTAGTGGDGLGTVNVSTASAILLSLINPVAKHGNRAVSGKSGSADVLEALGYNIIVPPERAKELVHKTNFVFLFAQYYHPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKSAYELDFNKVILVHGEPGIDEVSPIGKTFMKIVSKRGIEEVKFDVTDFGISSIPIDKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDKVSDFKEGYEYAKYLIENSVNKLNEIISLNGDLTKLKTIMVKSSG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL24_SHISS
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RNM_ASPPH
Sequence: TIDTCSSDSPLSCQTDNEASCCFNSPGGSLLQTQFWDYDPSDGPSDSWTIHGLWPDNCDGSYQEYCDDSREYSNITSILEAQDRTELLSYMKEYWPDYEGADEDESFWEHEWNKHGTCINTIDPSCYTDYYAQEEVGDFFQQVVDLFKTLDSYTALSDAGITPSEDATYKLSDIEDALAAIHDGYPPYVGCEDGALSQLYYYFNVKGSAIGGTYVASERLEDSNCKGSGIKYPPKSSS
What is the function of this protein?
This is a base non-specific and adenylic acid preferential ribonuclease.
What are the official names of this protein?
Ribonuclease M, RNase M.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: EXU1_DROPS
Sequence: MVAEISKDCVTIAAADQCVDMKEELPAGNYILVGVDVDTTGRRLIDEIVQLAAYTPKDNFQQYIMPYMNLNPAARQRHQIRVISIGFYRMLKSMQTYKIIKSKSEVAALMDFLNWLEMLVAKQPSTDGIVMLYHEERKFIPYMVLEALKKYGLIERFNRTVKSFVNTFNMAKASLGDANLKNCGLRKLSLLLAKSNDESANKENEPENVNRNGSSNDKCHKNGMNQEHDFFEGSANVRAKMVYEVALQLTNSDRTSEPESSEELVNLFNAVKPFAKLVSSDIMELQTQNENMGRQNSFRPVFLNYFRTTLYHRVRAVKFRIVLAENGFTLDSLKAIWTEKRKEGLELALTNIDTLKTEEKTELVELLDSFFDPSKATIKPSFKPNGNGPRRRIRANGAASSKNGAMSSRSTSTEFGAGGDKSQTEGLSAPVPDSTTKSPSPGKTGGRPHRKRNNTRNGFGSAKGPKKAETLNIAAPEPPQSPVAVSTPVAIAATN
What is the function of this protein?
Ensures the proper localization of the mRNA of the bicoid gene to the anterior regions of the oocyte thus playing a fundamental role in the establishment of the polarity of the oocyte.  May bind the bcd mRNA (By similarity).
What are the official names of this protein?
Maternal protein exuperantia-1.
Protein: YRAN_ECOK1
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFIEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y246_CALS4
Sequence: MDKVFELKNVSYFYTPKVPALIDISFDVKLKEKLFILGANGSGKSTLLKLMDGLIYPHEGQIRFFGKVIGDKRTFDEYEFRRRVGFVFQDSDVQLFNTTVFDEIAFAPLQMGVKKEEVEKLVNEILISFGIEKLKDRPPHRLSGGEKKKVALASIIVINPDVLLLDEPTNGLDPRSKKWLLSKLEELNQKGATLVIATHDLEMAKKFSDRIIILNEEHKIETIGSPEEILNDEKLLLKANLI
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein TTE0246.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FTSZ_WIGBR
Sequence: MFEPIELTSDAVIRVVGIGGGGGNAVEHMVRECIEGVDFFAVNTDAQALRKTEVSQTVQIGSSITKGLGAGANPEVGKNSAEEDKDALRIILDGADMVFIASGMGGGTGTGAAPVIAEIAKDLGILTVAVVTKPFNFEGKKRLIFAEQGIDELSKHVDSLIIIPNDKLLKVLGKGISLLDAFSAANDVLKNAVQGIAELITRPGLINVDFADVKTVMSEMGYAMMGSGISKGDNRAEESSEIAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFEAVGNKVRSFSSDNATVVIGTSLDPSMNDELRVTVVATGIGMDKRPDIKLVTNSTSNKNIMDRFGYRYSDKENTMSKNNNEFSKIKNKTKEDLQSDYLEIPAFLRNQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: CYSC_ENT38
Sequence: MAQHDENVVWHPHPVTVAQREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALYQQGVSTYLLDGDNVRHGLCSDLGFSDDDRKENIRRVGEVASLMADAGLVVLTAFISPHRAERQMVRERVGHDRFIEVFVDTPLAICETRDPKGLYKKARAGELKNFTGIDAVYEAPESPQIHLDGQQLVTNLVSQLLDLLRQDDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ATPE_MYCTO
Sequence: MAELNVEIVAVDRNIWSGTAKFLFTRTTVGEIGILPRHIPLVAQLVDDAMVRVEREGEKDLRIAVDGGFLSVTEEGVSILAESAEFESEIDEAAAKQDSESDDPRIAARGRARLRAVGAID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YKD1_YEAST
Sequence: MQYDYGTEDNEVNHIYSENERQKERENECAGPCLYLAPPADVCIFFLFPFVLSPRGGGKEKKKKKVRKVRCASPLLLLHPDITPNTKPRAAVVSNRSTHSSTVCRSLSTMCMFYGYVPIFSAFGIIFCFDNYRSCYC
What are the official names of this protein?
Putative uncharacterized protein YKL031W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPF_NITOC
Sequence: MRIGHGFDAHRFGSTGKLILGGVEIPHEQGLIAHSDGDVVIHALCDALLGGAALGDIGRHFPDTSAEFKNADSQKLLHRVMVLLKEHGFKVSNGDMTIIAQIPKLAPYLPAMRETLALALGLPLQRFNIKATTTERMGYIGRAEGIAAHAVVLLLEEQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PBL7_ARATH
Sequence: MGWIPCSGKSSGRNKTRRNGDHKLDRKSSDCSVSTSEKSRAKSSLSESKSKGSDHIVAQTFTFSELATATRNFRKECLIGEGGFGRVYKGYLASTSQTAAIKQLDHNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDKTMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSHVSTRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYLASQKFDPLAQPVQGSLFAPGTPPRSKRV
What is the function of this protein?
Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth.  Phosphorylates both BSU1 and BSL1 in vitro.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL7, CDG1-like protein 1, PBS1-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: TIM22_ASHGO
Sequence: MVYRGFGLEHISPPVNKPFAEMTPEEQGERGAQMMMEFMTSCPGKSAISGVTGFALGGVFGLFMASMAYDTPLHTPAPVGAGPGAGIPGAPTLQQMADLPLKQQIKIQFADMGRRAYSSAKNFGYIGMIYSGVECTIESLRAKNDLYNGVAAGCLTGGGLAYKSGPSAALIGCAGFAAFSTAIDLYMRSENGRPPKNDFDE
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PTC_STRRT
Sequence: MMKKTDYITTEDFSKEELLKLVDLSLKIKACIKNGYYPPLLEHKSLGMIFQQTSTRTRVSFETAMSQLGGHAQYLAPGQIQLGGHETIEDTSTVLSRLDDILMARVERHQSVVDLARCASIPVINGMSDYNHPTQELGDLCTMIEHLPAGKKLEDCKVVFVGDATQVCFSLALITTKMGMEFVHFGPKGFQLNDMHKEELDKICELSGGKYTVTDNEDAIEGANFLYTDVWYGLYEAELSEEERMQIFFPKYQVDSQMMAKAGADCKFMHCLPATRGEEITDEVMDGPHSICFDEAENRLTSIRGLLVYLLRDYREKNPYDLVKQEKAKEELETFLKPE
What is the function of this protein?
Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine.  Is involved in the degradation pathway of the polyamine agmatine.
What are the official names of this protein?
Putrescine carbamoyltransferase, PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_CHLTR
Sequence: MTHKLTPMMQQWHQCKEQAGDCLLLFRLGEFYEAFFDDALILAQNLDITLTQRQNVPMSGIPATCLDGYVDRLVSRGFKVAIAEQADNTEGSKGLVPRTINRLITPGALLSSSLLPEKANNYVLAINQVGSLYGLSCLDLSIGTFLVAEYDNTKDLIEAICRLAPTELLSHAKFYQKNEAVIKQLQQHLRITLSEYVSWAFEYQSATKKLYTCFQVSSLDGFGLQGLVPAINAAGALLSYIQDKLLLPISHLSIPKIYGQQKHLLIDKASQTNLELLSPIHGEHGKGSLLQVMERTSTPMGGRLLRNTLINPFYDLKEITLRQDSVEFFLQQADLRKILKRQLSCVRDLERLATKISTSLATPKDIGTLRDSLLSCTHIADNLQNCALPEFLENKFLIAPPLCSLIKTLSTELIQELPLKVSEGNIFANHYHPDLLRLRNIKENSKSWILEYQERIRNETGIKKLKVCYAQALGYYIEVASNLAPQLPKEFIRRQSRLHAERFTTQELQQFQDEVFSVEDKLQTLETKLFKELCFYIVEHRDLILKLSTAVADLDYVVSLAELAAEYDYRRPLVDHSDALSITKGMHPVALTLLDKGTFIPNDTVMHSAQTRMILLTGPNMAGKSTYIRQIALLVIMAQMGSFIPARSAHIGIVDKIFTRIGAGDNLSKGMSTFMVEMAETANILHNATDRSLVILDEIGRGTSTYDGLAIAQAVVEFLLFTDGKKAKTLFATHYKELTELEMHCQHVENFHAMVKENSGQPIFMYEIVKGHSKKSFGIHVAKLAGFPLSVVSRAQQILHQFEGPDLRPEPEKAQQLVMF
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FLOA_PRIM3
Sequence: MEVGSVLFFVVIGLAIIALAVFFTFVPIMLWISALAAGVRISIFTLVGMRLRRVIPSRVVNPLIKASKAGLGITINQLESHYLAGGNVDRVVNALIAAHRANIELTFERGAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMDGIEVKAKARITVRANIDRLVGGAGEETIIARVGEGIVSTIGSQTDHKKVLENPDMISQTVLGKGLDSGTAFEILSIDIADIDIGKNIGAVLQTDQAEADKNIAQAKAEERRAMAVAQEQEMRAKVEEMRAKVVEAEAEVPLAMAEALRSGNIGVMDYMNIQNLTADTDMRDSIGKMSKEDDEK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: RPIA_VIBA3
Sequence: MTQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKLEALEIKVFECNDVFKLDIYVDGADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGTKAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGCTTDNGNVILDVYGMAIENPKQLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: NPBL_COPC7
Sequence: MDHNSNHHWYSQNRPRNDPRIPSQQSPNTNINHHGFTNAANQTVQHAQQMLAGFPMASATPALQPVRHIANMTMTAAPPSFVQPNYYSSQAQPDYTHVQQHNSQHIPPPPYTEYDQHLSYLSAPQVPQNRTEHWHTARDQSVRLLNEQASRSYPYQEPQQPSNWPASSYQSTPFAQSVFQRTTPNSAYPTPPPPGISTSSSSLAFALGGPPQPPPRQQTVTQPLFHPTQAPLPQPAPAPQPAPVPQATVFPPPSNPPAAQASQPTYNADDSASFFNSFLERKTREMNATMQQTTSAKSIFPPAPAKLPLPVPVASKPPARMKTPPPREQKAVPDSSPDPLSLSSNMALPSSTPLKRKCVVEIHSPPPKRIQSYKPMTLISQPLTPSRGPPLTPTSRASNASSVPTTASSSTSITSMSSSSKTTVPMTPTPQRIGRKYEDTPDLGGYGSSEDTPLRRGLMSSVKRTGERDDRGPLEKFVTVVDEIFESEDSLPADLGHEDLPQEFFSSWSPDCSKPLLNTSTIRKLLKYVGQVARPTKRMRQASAGGQGLLATPRTRAGRMADVDIQTLSRLLKMLERSLKEGEEVDPFKATGSSSGLNGTVSARSSPVKKGSRKKKAKDSLDDDDSMEADEADELPQQHLKKGSTPPPNDIELEKLTRLLDLARDSVLAADCCIAILASDRLPKQLYSEELITSCLNTVKNQLTKVLYPFIEGASPDSINSKLYNGALLQHLIKNAPADPNTSANSSISQAYHRKQMSEIFQSLSSVLPRINALANAESVAMSDSIIIQTVYIAIGPFFVVEGAEESTAKSASKKEKESVVNRTLGKSAMRGLRLDALSLIRSIFSNHEDQRSWIIEEILTSLIKLSDTKQKAGQFRLRDGRSIRTVSALLMQLVQTSAHDVRINARRLEKERQNALALKRQESISDLNGQPKSDEPFLDNIDMEEIRLYGGGLESATKAAKTIIFFLNSRAGKGKTTKNSNEAEYRAIFDNLIDDLLVVLYWPEWPAASLLLNIASKFMVSSLDDVKSNAQIDTNAAKSMALDHLGVIAARIRSSILKVQKDEDGTSYRGLKPLDEIVNNLQSKQFAKFMDAHRDVAAHLCKRSTEDQAYESARELTAAILGHELAASLKRVNVWLDHPEQDEDLDLRDSSKALSFGQKLKTALREVWKDPATDVFDIGSQEEVSRIDRLSEEIGTIQSLRNSFQPILNVILSALDAPVIFMRTKALRALGQIVTSDATILGTASVRQGIENHLLDSSPAVRDAAVELIGKYMIDSPEVAGNYYQKIAERMADTGLAVRKRVIKLLKSYYGVIDDTQRKIDISARLVLRMVDEDDGVKDLAMKTLEELWFPPLPPPSAMKVKPTSSSNPNQDKAALLSKVAIIMGTAANFRDRQSPLEDMLHKIISDKEGNEAASLHQRYAEICETLIDGLVDATDLPGFTIINCIRTIHLFTAAYPSILPGTHASTLLPYLKNASTTEELLTSDFLLKIFRASIPHMPKTAAKFGQELQTSLQPLILKPFGGVNILQEAVGCMCAVVRHLTHDFKRLINLLKGCNARLLSYLRHPPTKQLNNVESKTLLMLLFIVALLGEHCNFDRLRLEQPDLAPDIDSITQGSVMEHIYFTLLRIYDKFDFADIRPRILQCLGFLFRAQPTLMTKEESAAIMDAIFASEEEEGRARLLKIMQDFLISESEKHSAKEKESAKNKNKANTDVNMEELVGNTDGFADSGVSSAIVQRYLSHILDAALSQNSQIQMAAIDVLTFTIKQGLAHPLQSFPVIIALETSPHAVLSARAIALHSILNSKHASLLNTRYSISARKSFDYQKKIVDGVVHGFRTNGHPTALLQRWYTLVREKRATRQDFLKSLVKVFSENDSYQATQDDVDFTRYMAENFASFEYKTQEEVFTVIKHLTTVLSTTGMQLLDIISPAHLLSQIQPSHSQPSQHNGGDEISSNAAEAVVPLATPNYGDRDPVSLMRTSVIVAMVMLLKSYLKTLYGLSEDKCNKFVIGKKSAIGDRPATKRSDKPISWEKLPYAVQAIHTTQDVELQKQRFLEIWNEDGVTAEPEDDEFL
What is the function of this protein?
Plays a structural role in chromatin.  Involved in sister chromatid cohesion during meiosis, possibly by interacting with the cohesin complex.  Also participates in DNA repair and meiotic homolog pairing.
What are the official names of this protein?
Protein rad9, SCC2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMG_SALPK
Sequence: MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEIRGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTADYPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFSHPQLADAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGARFFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQANVVFVDESPMAVDSSRLNVETNLPEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCCP_ECO57
Sequence: MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVMQQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAFIEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.
Protein: SUCC_BREBN
Sequence: MNIHEYQGKEILKQYGVKVPEGRVAFTVEEAVEAAKELGTQVNVVKAQIHAGGRGKAGGVKVAKNLDEVRTYASEILGKVLVTHQTGPEGKEVKRLLIEQGCDIKKEYYVGVVVDRATGSVVMMASEEGGMDIEEVAANNPEKIFKEVVDPVTGLNGFQARRLAYAINIPKELINKAAKFMMSLYQAFVDKDASIAEINPLVVTGDGEVMALDAKLNFDSNALYRHPDIVALRDLDEEDEKEIEASKFDLSYIALDGNIGCMVNGAGLAMATMDIVKFYGGDPANFLDVGGGATEEKVTEAFKIILRDEKVKGIFVNIFGGIMKCDVIANGVVNAAKQIKLDKPLVVRLEGTNVDLGKKILNESGLNIVAAESMADGAEKIVSLVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: OGFD3_RAT
Sequence: MAPQRRGPPRVPEGNSAAERRHANSTKKDRLPQEAQRTWLRIVALGVSLALVTFLLWSSAGIDDDVAEVVAHRGEVLEGRFIEVPCSEDYDGHRRFEGCTPRKCGRGVTDIVITREEAEQIRRIAEKGLSLGGSDGGASILDLHSGALSVGKHFVNLYRYFGDKIQTIFSEEDFQLYRDIRQKVQLTIAEAFGIRASLLYLTKPTFFSRINSTEAQTAHDEYWHAHVDKVTYGSFDYTSLLYLSDYLEDFGGGRFVFMEEGSNKTVEPRAGRVSFFTSGSENLHRVEKVLWGTRYAITIAFTCNPDHGIEDPVLT
What are the official names of this protein?
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the OGFOD3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RPE65_AMBTI
Sequence: MTNRVDHPAGGYKKLFESTEELVAPVTAQVTGRIPVWLSGSLLRCGPGLFEVGSEQFYHLFDGQALLHKFEFKGGHVIYHRRFIRTDTYVRAMTEKRIVITEFGTFAFPDPCKNIFSRFLSYFQGLEVTDNALVNVYPVGEDYYACTETNYITKINPETLETVKKVDLCNYVSINGVTAHPHIEHDGTVYNIGNCFGKHFAFAYNIVKIPPLQADKEDPINKAKVVVQFPCSERFKPSYVHSFGLTPNYIVFVEQPVKINLFKFLSSWSIWGANYMDCFESHETMGVWMHVAEKHTGEYLNIKYRTSAFNLFHHINTYEDHGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRSAEKPPQPEVRRYVLPLDIHKVDTGKNLVNLPYTTATAVLRSDETIWLEPEVLFSGPRQAFEFPQINYKKHGGKDYTYAYGVGLNHFVPDRLSKLNVKTKETWVWQEPDTYPSEPIFVSQPDAIEEDDGVVLSVVISPGEGQKPAFLLILNAKDMSEIARAEVDSNIPVTFHGMFKKA
What is the function of this protein?
Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore.  Essential for the production of 11-cis retinal for both rod and cone photoreceptors.  Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid.  The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.  The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.  The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT.
What are the official names of this protein?
Retinoid isomerohydrolase, All-trans-retinyl-palmitate hydrolase, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Microsome membrane. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
Protein: SK1_PSEFV
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, PseFl-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SAMP_SALSA
Sequence: AHQDLSGKVFVIPMATSTSHVKLHARVSEPISAMTM
What are the official names of this protein?
Serum amyloid P-component, Agarose-binding protein, Ss-ABP.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_THESQ
Sequence: MKRTYQPSRRKRKRTHGFLARKRTPGGRRVLKNRRRKGRWRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.