PharMolix/UniProtQA huggingface dataset:
Protein: SPEA_NEIMA
Sequence: MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQIVSLQKLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEKLGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQLLHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYAATVVWGISQACLEHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDLADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVCPITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVVVGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: LYS12_SCHPO
Sequence: MSATRRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGKPVDLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVLANIHN
What are the official names of this protein?
Homoisocitrate dehydrogenase, HICDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: PGLRB_ASPKA
Sequence: MHFLQNAFVAATMGAAPAAATPLEKRSCTFTSASAAKSGKSSCSTITFDNIAVPAGETLDLTGLKKGTTVIFEGETTFGYKEWKGPLISMSGTDITVKQASGAKINCDGARWWDGKGSNGGKTKPKFFQAHKLDESSITGLKIYNTPVQGFSILADHLTITDVTIDDSAGTSKGHNTDAFDIGQSTYITIDGATVYNQDDCLAINSGEHITFTNGYCDGGHGLSIGSIGGRSDNTVNDVTISNSKVVNSQNGVRIKTIYGKTGTVENVKFEDITLSDISKYGIVVEQDYENGSPTGTPTNGVKVEDITFKKVTGSVKSSGTDIYILCGSGRCSNWTWSGVDVTGGKKSSKCKNVPSGASCSD
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase B, Pectinase B, Polygalacturonase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_STAAM
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RRN3_PONAB
Sequence: MAAPLLHTRLPGDAAASSSAVKTLGASRTGISNMRALENDFFSSPPRKTVRFGGTVTEVLLKYKKGETNDFELLKNQLLDPDIKDDQIISWLLEFRSSVMYLTKDFEQLISIILRLPWLKSQTVVEEYLAFLANLVSAQTVFLRPCLGMIASHFVPPRVIIKEGDVDVSDSDDEDDNLPANFDTCHRALQIIARYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISVYFPTLRHEILELIIEKLLKLDVNASRQDIEDAEETATQTCGGTDSTEGLFNMDEDEETEHETKAGPERLDQMVHPVAECLDILMSLVLSYMKDVCYVDGQVDNGKTKDLYRDLINIFDKLLLSTHASCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPSNPAIIRQAAGNYIGSFLARAKFIPLITVRSCLDLLVNWLHIYLNNQDSGTKAFCDVALHGPFYSACQAVFYTFVFRHKQLLSGNLKEGLRYLQSLNFEWIVMSQLNPLKICLPSVVNFFAAITNKYQLVFCYTIIERNNRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCVLKRSKKFIDPIYQVWEDMSAEELQEFKKPMRKEIVEDEDDDFLKGEVPQNDTVIGITPSSFDAHFRSPSSSVGSPPVLYMQPSPL
What is the function of this protein?
Required for efficient transcription initiation by RNA polymerase I.  Required for the formation of the competent preinitiation complex (PIC).  Dissociates from pol I as a consequence of transcription.  In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).
What are the official names of this protein?
RNA polymerase I-specific transcription initiation factor RRN3.
What is the protein family that this protein belongs to?
Belongs to the RRN3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YBEY_ACTP2
Sequence: MTTPIIDLQIAAENSENLPSLAQFTQWVQRALAHEAQTEDFPETEITIRIVDEAESYELNLTYRGKDKPTNVLSFPFEVPEGIELPLLGDLIICRQVVEKEAQEQQISLESHWAHLAIHGTLHLLGYDHIEDAEAEEMEGLETEIMQSLGFEDPYISEKVIEE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_EXIS2
Sequence: MSYKQQYAQVLHDVIGDALSQEEIEQLIEQPKHEDHGDLAFPCFQLAKAFRKAPMMIATELAEKIDNPLFSNVQAAGPYVNVFLNREVVSREIIKRVLEEQQAYGSSELNGKTIVTDFSSPNIAKPFSMGHLRSTVIGNALNQISRKKGYEVVGINHLGDWGTQFGKLMVAYNMWGKEEDVRSEPIKELLKLYVRFHEEAEENPGLEDEGRAWFKKLEQGDEQATALWTWFREVSLVEFSRVYEMLGVSFDSLNGEAFYNDKMQHVIDLLEEKDLLVESEGAMVVDLEAEGMPPALIKKKDGATLYATRDLAAAVYRLETYGFEQAFYVVGGEQALHFKQLFAVLKKLGFENVDGMHHVPFGLIMKDGKKMSTRKGRIVLLEEVLQDAINVAKQNIAEKNPNLANAEQTAREVGVGAVIFHDLKNERMNNIEFDLEQMLKFEGETGPYVQYTNARANSLLRKGAYDGSAFNGSADDYSWGVVSMLNQFSAVIDRAFTRREPSIISRYVLDLAQSFNKYYGQVRVLEDDAEKQSRLALVKSVTIVLTEGLRLLGVGAPEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_ECODH
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: SEPF_GLOC7
Sequence: MNTILTKLKDFVGISEHDDEYETDYEEMEYDRYSKTNSSETLAPEEEEPIRNRRTRESLNLTSDVPMGTTTRNNVIGMPGITNGIAEVVVIEPHSFEEMPQVIQTLRERKSVVLNLNVMDPEEAQRAVDFVAGGTYAIDGHQERIGESIFLFTPSCVKVSTLTGTVHDVPETPKATTRPTMSTPVWGAEASRIAQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: CSN2_ARATH
Sequence: MASDADMEDYGFEYSDEEQEEQDVDIENQYYNSKGMVETEPEEALSGFAEVVQMEPEKADWGFKALKQTVKIYYRLGKYKEMMEAYTEMLTYIKSAVTRNYSEKCINNIMDFVSGSASQNTGLLQEFYQTTLKALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKEDGTDDQKKGSQLLEVYAIEIQIYTETKDNKKLKQLYHKALAIKSAIPHPRIMGIIRECGGKMHMAERQWEEAATDFFEAFKNYDEAGNQRRIQCLKYLVLANMLMESEVNPFDGQEAKPYKNDPEILAMTNLIAAYQRNEIIEFERILKSNRRTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGIPFISKELNVPETDVTELLVSLILDSRIDGHIDEMNRYLLRGDSGNGRKLHKAVDKWNSQLKSLSSNITSRVC
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes.  The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.
What are the official names of this protein?
COP9 signalosome complex subunit 2, Signalosome subunit 2, Protein FUSCA 12.
What is the protein family that this protein belongs to?
Belongs to the CSN2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYT_LARHH
Sequence: MPAIRLPDGSVRQFENPVSVHDVAASIGAGLARAALAGRVDGALVDTSFVIDHDVDLAIVTDKDADGLGILRHSTAHLLACAVKELFPEAQVTIGPEIENGFYYDFSYKRPFTPEDLVAIEKKMAELAKKDIPVERYELPRDEAIAYFKSIGEAYKAEIIESIPQGEVLSLYREGNFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEMLQRIYGTAWAKKEDLEAYLHMLEEAEKRDHRKLGRQLDLFHIQDEAPGMVFWHPKGWTLWQQVEQYMRRVLIANDYQEVRTPQIVDRSLWEKSGHWAMYQDLMFTTESEKRDYAVKPMNCPCHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGIMRVRNFVQDDAHIFCTEAQMQPETAAFIDLLQAVYQDFGFDNILIKLSTRPEKRVGADELWDQAEAALAAALAAKGLAYELQPGEGAFYGPKIEFSLKDCLGRVWQCGTLQLDFNLPVRLGAEYVSEDNAKKHPVMLHRAILGSLERFIGILIEHHAGAMPLWLAPVQMAVLNITEAQAEYATEVAETLKKQGFRVDLDLRNEKISYKIREHSLQKLPYQIIVGDKEKAGALVAVRARTGEDLGQIPLSQFIERLKSELLH
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STAAB
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ILVD_BRUSU
Sequence: MPPYRSRTTTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIESAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKVVWEDSVKKLDLVDAMVAAADDHYTDEQVKAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVDLARRYYEQDDESVLPRSIATFSAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMADIDRLSRRVPVLCKVAPAVSSVHMEDVHHAGGIMGILGQLDNAGLLTTSIPTVHSETLAKALDHWDVTRTNSEMVHKFYSAAPGGVPTQVAFSQERRFDKVDTDREKGVIRSKEHAFSQDGGLAVLYGNLAEDGCIVKTAGVDDSILKFSGPARIFESQDSAVLGILNGKIKPGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGFGKACALITDGRFSGGSSGLSIGHVSPEAAEGGTIGLVREGDIIDIDIPNRKIHLAVDDATLAERRAEQDAAGWKPAEERKRKISTALKAYAAMATSAARGAVRKLPD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: 5BPOR_DIGLA
Sequence: MSWWWAGAIGAAKKRLEEDDAQPKHSSVALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRTRPAWHEDNPINYVQCDISDPDDSQAKLSPLTDVTHVFYVTWANRSTEQENCEANSKMFRNVLDAVIPNCPNLKHISLQTGRKHYMGPFESYGKIESHDPPYTEDLPRLKYMNFYYDLEDIMLEEVEKKEGLTWSVHRPGNIFGFSPYSMMNLVGTLCVYAAICKHEGKVLRFTGCKAAWDGYSDCSDADLIAEHHIWAAVDPYAKNEAFNVSNGDVFKWKHFWKVLAEQFGVGCGEYEEGVDLKLQDLMKGKEPVWEEIVRENGLTPTKLKDVGIWWFGDVILGNECFLDSMNKSKEHGFLGFRNSKNAFISWIDKAKAYKIVP
What is the function of this protein?
Involved in cardenolide biosynthesis.  Catalyzes the stereospecific conversion of progesterone to 5-beta-pregnane-3,20-dione.  Can use progesterone, testosterone, 4-androstene-3,17-dione, cortisol and cortisone as substrates, but not pregnenolone, 21-OH-pregnenolone or isoprogesterone.  NADPH could not be replaced by NADH.
What are the official names of this protein?
3-oxo-Delta(4,5)-steroid 5-beta-reductase, Delta(4)-3-oxosteroid 5-beta-reductase, Delta-4,5-steroid 5-beta-reductase, At5beta-StR, Progesterone 5-beta-reductase, 5beta-POR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. Highly divergent.
Protein: CTBP1_CAEEL
Sequence: MPTTCGFPNCKFRSRYRGLEDNRHFYRIPKRPLILRQRWLTAIGRTEETVVSQLRICSAHFEGGEKKEGDIPVPDPTVDKQIKIELPPKESKNSDRRRKQNIPARFPRPESPSGDSPSYSKKSRSFRDFYPSLSSTPSFDPAQSPHTPHPPVLPDPQQALNDILSMTSTRMNGPSSSRPLVALLDGRDCSVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVAALMYHSIKLEKEDLEKFKVLKVVFRIGYGIDNIDVKAATELGIAVCHAPGDYVEDVADSTLSLILDLFRRTYWHAKSYSETRKTIGADQVRENAVGSKKVRGSVLGILGCGRVGTAVGLRARAFGLHIIFYDPFVREGHDKALGFERVYTMDEFMSRSDCISLHCNLGDETRGIINADSLRQCKSGVYIVNTSHAGLINENDLAAALKNGHVKGAALDVHDSVRFDPNCLNPLVGCPNIINTPHSAWMTEASCKDLRINAAKEIRKAINGRCPQDLTHCINKEAVMRNSNPINRRTSSAHPLLNMGFPTLPNFPPMSMSPHFPYPNPLLAMGAQMGALNPFMGNGALPFNPAAALSSLAAAQAANAQRGSPANRSSRSSPSPHTNKSSVSPGNNGHVKTEPSSPAAKIEVDIAENDKHSMMTFLQRLIAPNGDSGASTADSGIEGGDKEKVQSDGDENMEDMEVIDAEKLKEELNIGQLEEPEEISVGLNNGNRINIDEQPLAT
What is the function of this protein?
Binds DNA and represses gene expression.  Plays a role in regulation of life span, possibly by regulating transcription of genes important for lipid metabolism.
What are the official names of this protein?
C-terminal-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: TRMB_ALKOO
Sequence: MRVRNISNAKELLKEYKEYVAAPQLFKEQWHTYFENQNPIHIEIGMGKGQFIRTLAKLNPNINYIGLEKVEELVLKSVRSIEAEEICNISLINWNAVKLEEILGEGEIERIYLNFSDPWPKARHDKRRLTHHGFLDIYQKLLKDHGEIHLKTDSKALFEFSLEQFTQKNFTLVEVIEDLHGSTDKEIAKTEYEEKFIAEGKPIYKCIARIE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: KHSE_STAAB
Sequence: MSNVLELKIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVAAKYSVDLPNLCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLISGYYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRALNRNVVTCHSELVDINVSGVKERIVYQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y758_METJA
Sequence: MVCSRGIFGIDIMNKKGIDSLFVSALYYSINKAIYDVMGDGGKVLGRRASYEMIKLLKDLGFIKENMSNEEIKNLFVNTFGLSEDLNIVEEDKKVIFEVINPTLDLFLKKLMEENLKPYVCPFMYLLSEIYSVSNNCRLMLSDVVPETEEKVKLIFKKV
What are the official names of this protein?
Uncharacterized protein MJ0758.
Protein: NUOH_ACIAD
Sequence: MRQTPLWAENWPIAYSVIQAIVILLVVVLVAALMSFIERRLLAWWQDRYGPNRVGPGGMFQIVADMLKIMFKEDWTPKFADKLTFRMAPAVAMATAVLSFIVIPVSPTLGVADMSIGLLFFMAMAGIAVYAVLFGGWASNNKYSLLGGLRSAAQTISYEVFLGISLMGVVAIAGSFNLREIVEAQRDMWFIVPQFLGFMIFVVAGVAVTHRHPFDQPEAEQELAEGYHVEYGGMKWGMFFVAEYVNIVLISALIVTLFFGGWLAPFNLEIPFIPPVFWFIVKTAFFVMMFVLARGALMRPRYDQVMNFGWKVCLPLALVNLMVTGAVILMNQA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU3_ACIFR
Sequence: MKKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPELVRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGRRKQLCSVDKANVLETTRLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVAMMLRHSLNAEPWAQRVEAAVQRVLDQGLRTADIAAPGTPVIGTKAMGAAVVNALNLKD
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.  Can also use D-malate and L-malate, with lower efficiency.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_STRP7
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREKGMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAEGKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNGGRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNESRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEAEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SYNSC
Sequence: MSRVCQLTGTRANNGMAVSHSHIRTKKLQQANLQQRRLWWAEGNRWVKLRVTTRALKTIQKKGLGAYAKSLGINLAKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: Y1815_STAA8
Sequence: MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase SAOUHSC_01815.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: GKAP1_RAT
Sequence: MASAVLSSVLTTASRFALLQVDSGSGSDSEPGKGKGRNNGKSQTLGNKSTANEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHSVCNVQHELSLPNPVQKESREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHRQDYENAENASTQTKVINKKDKRKNHQGKDKPLTVSLKDFQCEDHISKKTEESNSSQPLSHDGGFFNRLEDDVHKILVREKRREQLTEHNGTDNCPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKAVVTQWEAKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALEQERSKVKVLQAELAKYQGGRKGKRNCEPDQCR
What is the function of this protein?
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase.  Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane.  Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
What are the official names of this protein?
G kinase-anchoring protein 1.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: TPIS_STAAR
Sequence: MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
What is the function of this protein?
Involved in biofilm formation (PubMed:11425708).  It also plays an instrumental role in adherence and invasion of the bacteria into the host cell (PubMed:22003920).  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).  It binds plasminogen.
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYREL_HALSA
Sequence: MKNVDDLIDDAAALADRGLSRGEIADELNVSRETASWLVERADTNASVAATDTDDSPRDVHVDWSTIGEAGARLSAIGIALADALRDHSHDVDLVVGIEKAGVPLATATANELGTDLATYTPRKHQWDEGDMADLGGSFSRNFASVEDRDCFVVDDTVTSGTTITETIQAVREAGGTPVACGVLADKQGLGDVDGTPIEALLQVIRVGSGDD
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: DNAG_SHIFL
Sequence: MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHNEKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAGSGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGFAPPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGFGGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQYGINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQLRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLSTLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTTMRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYRGTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNEERLELWTLNQELAKK
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: I364_CONLT
Sequence: MKLVLAIVLILMFLSLSAGAETSDNGVSRGGHRPQYWPVTPPSIVCLRSGEDCENNTPCCPGLSCRVSADLATLKLSLACD
What are the official names of this protein?
Conotoxin Lt6.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4284_JANSC
Sequence: MREFEAHGATASPGVVTNFLGVRIPSDIMPSILKSLEGQKEGFPIPGNWHADIAEWAAALLSVREAKTSYRILEVGCGWGCWLSNMGVAAKARGLKIDLIGVEGDQQNIEHAKHTLALNGIEAHEFQLTNGVASARNGVALFPILDGPGEVWGAEPIFHPDAETISKARAAGSHTELKCYTLDDLSHGKPIDLLHVDIQGSELDFVKGNFDEISTLVKRILIGTHSRYLEGSLQKFLLDQGWALEMDRPAICTNVAGKPQIAVDGVLLFRSPTMPHPVF
What are the official names of this protein?
Putative methyltransferase Jann_4284.
Protein: IHFB_SHIF8
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.