PharMolix/UniProtQA huggingface dataset:
Protein: RF3_SALTI
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWAPAPMPRQTDTRTVEASEERFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTMVNLNLTQERYPDVQFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_HELMI
Sequence: MNQPSLDKLMEKVDSKYTLVVLAAKRARALVEKQAPLVSVAKSAKPVSIALHEIVDGKVSYRQAKGGIK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CRSH1_ORYSJ
Sequence: MATAATTSAAAIPTGGGGRRQHPHPRRPGLRPRRLHRLRLPAQAAAAAAASSPSTSSSSSSSSTPAEGGGRLVAELVGAFNELTGRMGEGLATSSSSRLLFRALKLALPALRDGDGGRALARALAIAASLADLQMDAEVISAGILREALDAGAISMRDVKSEIGISTAHLLHESLRLKHAPSKLDVLDDESASALRKFCLSYYDIRAVILELALKLDMMRHLDCLPRYLQRIKSLEVLKIYAPLAHAVGAGNLSLELEDLSFRYLFPHSYDHIDQWLRSQETENKLLIDSYKEQLLQALKDDDELSQIVQDISIQGRYKSRFSTMKKLVKDGRKPEEVNDILALRVILEPRCDGSSLDWGPRACHRTHEIIQAMWKEVPGRTKNYVTRPKENGYQSLHVAIDVSEPGKMRPLMEIQIRTKEMHKFAVGGEASHSLYKGGLTDPGEAKRLKAIMLAAAELAAMRLRDLPASDQGDSNCTNRAFCQLDKNGDGRISIEELTEVMEDLGAGGKDAKELMHLLDANSDGSLSSDEFEAFQRQIELMRSLDDKDDRYRKILKEKLQTIDSAGLIQVYRKQLGDKLLVS
What is the function of this protein?
Possesses calcium-dependent ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase activity in vitro and is able to functionally complement E. coli relA mutants.  May be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses.
What are the official names of this protein?
GTP diphosphokinase CRSH1, chloroplastic, Calcium-activated RelA/Spot homolog 1, OsCRSH1, ppGpp synthetase CRSH1.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPH_BACCZ
Sequence: MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIPTDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIKLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ULAF_ECO5E
Sequence: MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAWAQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTPGIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRKHGPNAYYGQK
What is the function of this protein?
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase UlaF, L-ascorbate utilization protein F, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: YP95_CAEEL
Sequence: MRLPRRLKIKRFHKPSCSSILPKYPGCPFSLNLSLSFLNFTHYDVHLQMINRFFPNVYYSVVIPIILLSTSYSAKIAPKCRDTDMNCAVWVATNTSDCENVELVNSHCPRTCQTCGEPIDPKYDVKLLPAKLKSIAWMVGRWRSEFGGKAFFPTIPKFTYGEQVDITIADNSQDTHTPLLNYTAFAWDINMPDGDPTEIHSENGYIAVEYDKEQEKEYVSLNTAMSNGFMTIEEGESGPNQVKFRLQRIGRISFSHDSAVRIMFREWTLLDENRLEARLLMTTTITRRLMEHTAVIYKKIYP
What are the official names of this protein?
Uncharacterized protein C28H8.5.
Protein: PYRB_STRA1
Sequence: MNHQTQTLSLEHFVSLEELSNQEVMSLIKRSIEVKENPSNIGFDKDYYVSNLFFENSTRTHKSFEMAELKLGLKTIEFNADTSSVNKGETLYDTILTMSALGLDVCVIRHPDIDYYKELIASPNIHSAIVNGGDGSGQHPSQSLLDLVTIYEEFGYFKGLKIAIVGDLTHSRVAKSNMQVLKRLGAEIFFSGPKEWYSSQFDEYGQYLPIDQLVDQIDVLMLLRVQHERHDGKGVFSKESYHQQFGLTKERYKHLRDTAIIMHPAPVNRDVEIASDLVEADKARIVKQMSNGVYARIAILEAVLNSR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ZN784_HUMAN
Sequence: MAAARPEAQSRSSPTPESRSQEPLDLVLVPDDCRPGTPPSDLIEIQVVKVTDTTLVPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLAGAEGGGQGGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCALCPRAFKALAPLLRHQHRHGVEPGTSRRPPDTAAVAEQRPGVAPERAEVVMAAAAAGAAVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCGICGKGFTQSSVLSGHARIHTGERPFRCTLCDRTFNNSSNFRKHQRTHFHGPGPGLGDSGGQLGSSAAEGSGSGCGVGDPAEEGRGETAKVKVEADQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 784.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL6_STRS7
Sequence: MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIKVEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: COBQ_THEP3
Sequence: MTLKLMVQGTASSVGKSLLVAAFCRIFKQDGYRVAPFKSQNMALNSYITDEGLEIGRAQAMQAEAAGIKPSYHMNPILLKPSSDRMSQVILRGKVYKNISAAEYHQFKPELLKLIKEDFDFLASQNDIVVIEGAGSPAEINLRDRDVVNMGMAEMTNAPVLLVGDIDKGGVFASIAGTLLLLKENERNRIEGVLINKFRGDIEILKPGLKMLEDIIHKKVLGVVPYMDVHIDEEDGSTERFYRRNTEGDIEIAVINLPHISNFTDFEPLAKIPGIKLRYVNKGERIGDCDVVIIPGTKNTIGDLQALKEYRIDKEIFEMRKKGKFIVGICGGYQMLGKVIKDPGRIESTTSEIEGLGLLDIETVIENEKTTTQIKAVIRNNLPSILSPLRNIAVEGYEIHMGQSRILGDCQPFSVITHRNGEKVEVYDGCISDDGKVFGTYIHGIFENREFVREFINIVRKSKGLSPIEEIIDYKEFKEREYDKLADIVRKSIDMKEVYKIMERYRD
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: HSLU_ENTFA
Sequence: MNELNKTPKEIVKELDQYIVGQQAAKKSVAVALRNRYRRLQLEENMQQDITPKNLLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMVRDLVENAIQIVEKQQYSRVYAQALKKANQRLVKVLVPGIKKEQKQAGGNQFEQMMNMFNMAQQQQEAQEEVTEDIRTNRRTILEQLEKGLLDNREVTIEIEEPKKTMPAMNNGLEQMGIDLNETLGALSPKKKIERTVTVKEAQELLVKEESAKIVNDADIHSEAIRLAESSGIIFIDEIDKITSKSQQNSGEVSREGVQRDILPIVEGSQVNTKYGPLQTDHILFIASGAFHLSKPSDLIPELQGRFPIRVELDDLTADDFVSILTEPNNALIKQYVALIGTENVSVIFTKEAIERLAHIAYDVNRDTDNIGARRLHTILERLLEDLLYEAPDMQMGEITITEAYVNEKLNDIVQNEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_MYCLE
Sequence: MGCNKRGVTRQEDDFSAWYNEVVAKAGLIDRGPAKGTMVIRPYGYRIWELLQDELDSKIKELGHENAYFPMLIPENYFNREAEHVEGFHPELAVVTHAGGKELSEPLVIRPTSETVIGDMMAKWITSHRDLPLRLNQWSNVVRWELRPRMLLRTIEFLWQEGHSAHIEKSDALRETLFALDIYTTLARDMAAIPIVSGEKTAGERFAGALNTYTIEAMMRDGKALQSATTHYLGDNFARAFNIRYTTAEEQQAFVHTTSFGLSTRMIGAIVMVHGDDKGLVLPPQVAPYQVVIVPITTGNKASEVGHAAADLARRLQAAGVRTHVDARPQLTPGWKYNEWELRGVPIRLELGPRDLEAGTTVMVRRIGEKAKQPIAIAAAPTELPGILEEFQRTLLERATQFRDDHTTLVDNWDAFATTVATGWALAIHCGNPECEEDIKAETAATPRCVPRQGAPATGRCIRCDAPSAYDKRVIFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_XANC8
Sequence: MNEYRSSLVFATPDVPLRDDVRRLGALVGDLLAEQVSADFLEEIERIRTTAIARRESDTPPAGLLSLLEGREPRAAEALVRAFSTYFQVVNIAERVHRIRRRRDYQRSGTDTPQPEGLHDALRRLKAQGVTLDELSEWLPRIDVEPVFTAHPTEAVRRALLEKEQLMVASLVDNLDGMRTPNERATDAARFRMALTASWQTADSSPVRPTVEDEREHVGFYLTQVLYRVIPVMYETLEHAIEETYGSTLALPRLLRFGTWVGGDMDGNPNVDAHTIAGTLDAQRRAVLDRYLNELWQLASLLSQSTTLVAVSPALSAQLERYQALLPDAAARSRPRHGDMPYRLLNDLMRARLQATLDDADGAYAAPAELEHDLQLILDSLQANKGLHAGWFAVRRLLWRVRSFGFHLARLDVRQESSVHARAVADALGQADWDSQDATHRAGLLGPYASGEQALPQVDDEGNARLDAVFAALADARTRHGADALGSYIISMAHNRADVLTVLALARRGGLVDDAGAVPLDIVPLFETVDDLRGGTGTVQDLLADPVYRQHLRARGDTQMVMLGYSDSGKDGGIAASRWGLQRAQVELLEAAAELGVRLTFFHGRGGSIVRGGGKTTRALDAAPRGSVDGRLRVTEQGEVIHRKYGIRALALRSLEQMTGAVLLSSLRPRAPEPREDAWRPVMDLVAERSTVAYRGFVGAPDFMQYFRLATPIDVIERMTLGSRPSRRLGQDAALSNLRAIPWVFAWSQARAVIPGWYGVGSGLQAAVEAGHEDSLREMAQDWPFFRTFLDDIAMVLSKGDLNIAELFSRLAGPLHARFFPRIRDELALTKHWVKTLLGQRSLLQHDPRLALSIRLRNPYIDPISVLQVDLLQRWRATDGEDEELLRALVACVNGVAQGVQNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: XYLA1_XANOR
Sequence: MSNTVYIGAKEYFPGIGKIGFEGRESDNPLAFKVYDANKTIGDKTMAEHLRFAVAYWHSFCGNGADPFGPGTRAYPWDVGNSALARAEAKSDAAFEFFTKLGVPYYCFHDIDLSPDADDIGEYESNLKHMVGVAKQRQADTGIKLLWGTANLFSHPRYMNGASTNPDFNVVARAAVQVKAAIDATVELGGENYVFWGGREGYACLHNTQMKREQDNMARFLTLARDYGRSIGFTGNFLIEPKPMEPMKHQYDFDSATVIGFLRQHGLDQDFKLNIEANHATLSGHSFEHDLQVASDAGLLGSIDANRGNPQNGWDTDQFPTDLYDTVGAMLVVLRQGGLAPGGLNFDAKVRRESSDPQDLFLAHIGGMDAFARGLEVANALLTSSPLEQWRAERYASFDNGTGADFAAGKITLADLAAHAAGNAPKQISGRQEAYENLINQYLTR
What are the official names of this protein?
Xylose isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5602_STRCO
Sequence: MIVGAGGGADMNARGAMGRYGETLAARRLTGAGMTVLERNWRCGRTGEIDIVARDGDVLVVCEVKTRRGGAFEHPMAAVTPDKAERLRRLAERWIQTHGGAPPGGVRIDLVGVLLPQRGAPVVEHARGVA
What are the official names of this protein?
UPF0102 protein SCO5602.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CP4A2_RAT
Sequence: MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes omega and omega-1 hydroxylation of saturated fatty acids.  Exhibits preferential omega versus omega-1 regioselectivity and (R) versus (S) stereoselectivity for hydroxylation of lauric and myristic acids (PubMed:10869363, PubMed:10620324).  Has low activity toward palmitic acid (PubMed:10620324).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:10869363, PubMed:10620324).
What are the official names of this protein?
Cytochrome P450 4A2, CYPIVA2, Cytochrome P-450 K-2, Cytochrome P450 K-5, Cytochrome P450-LA-omega 2, Lauric acid omega-hydroxylase, Long-chain fatty acid omega-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: GATB_CUPPJ
Sequence: MQWEVVIGLETHTQLSTASKIFSGTSTAFGAEPNTQASPVDLALPGVLPVLNKGAVERAIQFGLAIGATIAPRSIFARKNYFYPDLPKGYQISQYEIPVVQGGSITIQVEGKKGEVYEKTVQLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPDMRSAAEAVAYAKALHSLVVWLGICDGNMQEGSFRCDANVSVRPVGQKEFGTRREIKNLNSFRFLQQAIEYEVQWQINEIEDGRKIQQATVLFDPDTGETRAMRTKEDAHDYRYFPDPDLMPLEIDAAWIERVRGELPELPAAMQARFVSQYGLSAYDASTLTASKAMASYYEAVVAEVGAANAKPAANWLMGDVASQLNREGISIDAAPVKPLQLARLLARIADGTVSNNTAKKDVFPAMWAGESNGDADAIIAAKGLKQMSDTGELEKIIDDVLAANAKSVEEFRAGKEKAFNALVGQAMKATKGKANPAQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RCEL_CERS4
Sequence: MALLSFERKYRVPGGTLVGGNLFDFWVGPFYVGFFGVATFFFAALGIILIAWSAVLQGTWNPQLISVYPPALEYGLGGAPLAKGGLWQIITICATGAFVSWALREVEICRKLGIGYHIPFAFAFAILAYLTLVLFRPVMMGAWGYAFPYGIWTHLDWVSNTGYTYGNFHYNPAHMIAISFFFTNALALALHGALVLSAANPEKGKEMRTPDHEDTFFRDLVGYSIGTLGIHRLGLLLSLSAVFFSALCMIITGTIWFDQWVDWWQWWVKLPWWANIPGGING
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: ACCD_NOSS1
Sequence: MANNEESRGLKSLFDWFANRRKAGATNPERQEREIADGLWHKCSKCGVLTYTKDLRANQMVCVECGHHNRVDSDERIRQLIDQNTWRPMDENLRATDPLQFRDRKAYSDRLREMEDKLGLLDAVKTGLGQINSSPVALAVMDFRFMGGSMGSVVGEKITRLIEQATQRRYPVVIICTSGGARMQEGMLSLMQMAKISAALERHRDARLLYIPVLTNPTTGGVTASFAMLGDIILAEPKATIGFAGRRVIEQTLREKLPDDFQTAEDLLKHGFVDDIVPRTQLKNTLSQLIALHQPVPTTPPMVLWETMSLSSTAVE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOD2_BOVIN
Sequence: MCAQDAFQTQRSQLVELLVSGSLEGFESILDRLLSREVLSWEDYEGLSLVGQPISHLARRLLDTIWNKGTWGCEQLTAAVREAQADSQPPELPSSWDPHSPHPARDLQSHRPAIVRRLYGHVEGVLDLTQQRGFISQYETDEIRRPIFTSSQRARRLLDLATVKANGLAAFLLQCIQELPVPLALPFEDAACKKYVSKLRTVISAQSRFLSTYDGAENLCLEEVYTENVLEIQMEVGMAGPSQQSPTTLGLEELFSTRDHFNKEADTVLVVGEAGSGKSTLLQQLHLLWASGRAFQEFLFVFPFSCRQLQCLVKPLSMRTLLFEHCCWPDLGPQDVFQVLLDHPERILLTFDGFDEFRFRFTDQERHCCPTAPTSVQSLLFNLLQGNLLKNARKVLTSRPSAVSASLRKHVRTELSLKGFSEEGIELYLRKRHREPGVADRLLCLLRATSALHGLCHLPVFSWMVSKCHEELLLQGRGSPKTTTDMYLLILRHFLLHASPLPLATHGLGPSLIQGRLPTLLHLGRLALWGLGTCCYVFSAKQLQAAHVDSEDLSLGFLVLAKRVVPGSTAPLEFLHITFQCFFAAFYLALSADTPPSSLRHLFQDHRPESSPLARVLPKLFLRGSRCREGSVAALLQGAEPHNLQITGAFLAGLLSQEHRSLLAECQASETALLRRWDCVRRCLTRSLREHFRSIPPALPGEAKSMHALPGFLWLIRSLYEMQEERLAREAVCRLNVGHLKLTFCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLVEHALRCEQLQKLALFNNKLTDGCAHSMARLLACKQNFLALRLGNNHITAAGAEVLAQGLRTNNSLQFLGFWGNQVGDEGAQALAAALGDHQSLRWLSLVGNNIGSVGAQALALMLEKNMALEELCLEENHVQDEGVCFLAKGLARNSSLKVLKLSNNHISSLGAEALLRALEKNDTILEVWLRGNTFSPEEIEKLSHQDTRLLL
What is the function of this protein?
Pattern recognition receptor (PRR) that detects bacterial peptidoglycan fragments and other danger signals and plays an important role in gastrointestinal immunity.  Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling.  This in turn leads to the transcriptional activation of hundreds of genes involved in immune response.  Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.  Component of an autophagy-mediated antibacterial pathway together with ATG16L1.  Plays also a role in sensing single-stranded RNA (ssRNA) from viruses.  Interacts with mitochondrial antiviral signaling/MAVS, leading to activation of interferon regulatory factor-3/IRF3 and expression of type I interferon.  Besides recognizing pathogens, participates in surveillance of cellular homeostasis through sensing and binding to the cytosolic metabolite sphingosine-1-phosphate and then initating inflammation process.
What are the official names of this protein?
Nucleotide-binding oligomerization domain-containing protein 2, Caspase recruitment domain-containing protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Basolateral cell membrane.
Protein: MRS2F_ORYSJ
Sequence: MRPSAAAGGGGGGGGRRKAAAAAAAASREWLVVPASGQARVEEAGKHAVMARTGLPARDLRVLDPLLSYPSTILGRERAIVVNLERVKAVITAAEVLLPNSKDPAFASFVCDLQARVLASSSDQAAEFTDMEGESSAVTSPFPALTSTTPNELEMTNKNSNVVGGMTHSNSMPTLTAAKDGNTKVLPFEFRALEVCLESACRSLEEETSTLEQEAYPALDELTSKISTLNLERVRQIKSRLVAISGRVQKVRDELEHLLDDEMDMAEMYLTEKLTRQEISETSSRVEVDDPSQLEVDRDEDYRSEADVSNGTFIGYKPHIEELEMLLEAYFVQIDGTLNKLSHLREYVDDTEDYINIMLDDKQNQLLQMGVMLSTATVVITAGVAVVGLFGMNIGISLYADPTNEEEKRASNMKFWETTLGTIAGCTVMYIVAMGWGKRSGLLQ
What is the function of this protein?
Magnesium transporter that may mediate the influx of magnesium.
What are the official names of this protein?
Magnesium transporter MRS2-F.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECR_METRJ
Sequence: MPQAVAGPEIERLIQLLARMPGLGPRSARRAALQLIKKRDTLLGPLADAMRVAADRIVVCTSCGNVDTSDPCTICRDAERDPTTLVVVEDVSDLWALERSGAVKARYHVLGGVLSALDGVRPEHLNLASLVERVARPEVTEVILALNATVDGQTTAHYVTESIRHCDVKVTRLAHGVPVGGELDYLDEGTLSAAIRSRTAF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MOAC_METNO
Sequence: MPSLTHLDATGAANMVDVSDKAPTARTARAEGTIVMLPETLRLIREGDAKKGDVLGTARLAGIMAAKRTHELIPLCHPLLLAKVRVDCEPDPALPGIRITAEVKVQGPTGVEMEALTAVSVACLTVYDMVKAADRGMRIEGIRLLQKSGGRSGLYEAEPA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: HISX_LEPBA
Sequence: MPIPILHCDRNSKELYSRFLQGAREDLTTATDRILPILESVRTQGDQALFSYTEMFDGIKLSQLTIDPKKIKTNVDEKTKEAFLRAKSNIEAFHMEQKRESWSKVIDGNRLGVKYTPIPSLAVYAPGGKALYPSSVLMGIIPAKIAGVPSIQLITPPQKDGIPEILVWLAQIMDIDRIVTVGGAQGIAAAAYGTESVPKSEFIVGPGNAYVAAAKSYLSGQGLIGIESPAGPSEVCIIADENANPKWIACDMLSQAEHGEDSSAILLTTDLTLAKRVSEELEIAFSERPKRLQMKQTAIYENSSILVFPTLDDCIWFSNELAPEHLEIQTKDYESVFAKIEHAGSVFLGPYSPVAMGDYISGTNHILPTARGSRIYSSLGVDTFLKRVTFQEVTKESLENLYPFVKLMSELEGLDEEHGTSVKVRTRQFQ
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: SLYX_PSEPK
Sequence: MTLEMRMVELETRQAFQDDTIQALNDVVVEQARVIERLQLQMAELIKRHEEMVGQYGSEGEEAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: SSRP_CLOBH
Sequence: MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPLRDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.