PharMolix/UniProtQA huggingface dataset:
Protein: ASB2_BOVIN
Sequence: MATEISARGRPRAIGQEEYNLYSSLSEDELVQMAIEQSLADKTRGPTTTETTVPTRVNREPAHFYPWTRSSVSPESALTSAPKGLFQEVMQKYNRSKSSQLAPVDPVLKAIKEDDEEALTAMIKAGKNLSEPNKEGWLPLHEAAYYGQLNCLKALHRAYPAVIDQRTLQEETALYLATCRGHVDCLQFLLQAGAEPDISNKSRETPLYKACERKNVEAVRILVQYKADTNHRCNRGWTALHESVARNDLEVMEILVSGGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDSASALYEACKNGHEEVVEFLLSQGADANKTNKDGMLPLHIASKKGNYRIVQMLLPVTSRTRVRRSGISPLHLAAERNNDEVLEALLGARFDVNAPLAPERARLYEDRRSSALYFAVVNNNVYATELLLLAGADPNRDVINPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCNGEPCFSCLYGNGPHPPAPPPSNRFNDAPASDKAPSAVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ
What is the function of this protein?
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Mediates Notch-induced ubiquitination and degradation of substrates including E2A and JAK2 (By similarity).  Required during embryonic heart development for complete heart looping (By similarity).  Required for cardiomyocyte differentiation (By similarity).  Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA (By similarity).  Also targets DES for proteasomal degradation (By similarity).  Acts as a negative regulator of skeletal muscle mass (By similarity).
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 2, ASB-2.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to the Z line in cardiomyocytes.
Protein: MOAC_NOSS1
Sequence: MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKGDVLATARLAGIMAAKQTANLIPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKSGDYFPPAP
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PROD1_ARATH
Sequence: MATRLLRTNFIRRSYRLPAFSPVGPPTVTASTAVVPEILSFGQQAPEPPLHHPKPTEQSHDGLDLSDQARLFSSIPTSDLLRSTAVLHAAAIGPMVDLGTWVMSSKLMDASVTRGMVLGLVKSTFYDHFCAGEDADAAAERVRSVYEATGLKGMLVYGVEHADDAVSCDDNMQQFIRTIEAAKSLPTSHFSSVVVKITAICPISLLKRVSDLLRWEYKSPNFKLSWKLKSFPVFSESSPLYHTNSEPEPLTAEEERELEAAHGRIQEICRKCQESNVPLLIDAEDTILQPAIDYMAYSSAIMFNADKDRPIVYNTIQAYLRDAGERLHLAVQNAEKENVPMGFKLVRGAYMSSEASLADSLGCKSPVHDTIQDTHSCYNDCMTFLMEKASNGSGFGVVLATHNADSGRLASRKASDLGIDKQNGKIEFAQLYGMSDALSFGLKRAGFNVSKYMPFGPVATAIPYLLRRAYENRGMMATGAHDRQLMRMELKRRLIAGIA
What is the function of this protein?
Converts proline to delta-1-pyrroline-5-carboxylate.
What are the official names of this protein?
Proline dehydrogenase 1, mitochondrial, Osmotic stress-induced proline dehydrogenase, Proline oxidase, Protein EARLY RESPONSIVE TO DEHYDRATION 5.
What is the protein family that this protein belongs to?
Belongs to the proline oxidase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: POLS_IBDV5
Sequence: MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSIGGELVFQTSVQGLVLGATIYLIGFDGTAVITRAVAADNGLTAGTDNLMPFNLVIPTNEITQPITSIKLEIVTSKSGGQAGDQMSWSASGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRAIRRIAVPVVSTLFPPAAPLAHAIGEGVDYLLGDEAQAASGTARAASGKARAASGRIRQLTLAADKGYEVVANLFQVPQNPVVDGILASPGVLRGAHNLDCVLREGATLFPVVITTVEDAMTPKALNSKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRDYTVVPIDDVWDDSIMLSKDPIPPIVGNSGNLAIAYMDVFRPKVPIHVAMTGAPNACGEIEKISFRSTKLATAHRLGLKLAGPGAFDVNTGPNWATFIKRFPHNPRDWDRLPYLNLPYLPPNAGRQYHLAMAASEFKDTPELESAVRAMEAAANVDSLFQSALSVFMWLEENGIVTDMANFTLSDPNAHRMRNFLANAPQAGSKSQRAKYGTAGYGVEARGPTPEEAQRKKDTRISKKMETMGIYFATPEWVALNGHRGPSPGQLKYWQNTREIPDPNEDYLDYVHAEKSRLASDEQILRAATSIYGAPGQAEPPQAFIDEVAKVYEINHGRGPNQEQMKDLLLTAMEMKHRNPRRAPPKPKPKPNAPTQRPPGRLGRWIRTVSDEDLE
What is the function of this protein?
Structural peptide 4 is a small peptide derived from pVP2 C-terminus.  It is essential for the virus viability (By similarity).
What are the official names of this protein?
Structural polyprotein, PP.
What are the subcellular locations of this protein?
[Capsid protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 4]: Virion. Host cytoplasm.
Protein: CYB_ANTCE
Sequence: MINTRKTHPLDKIVNNMFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALTMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILTLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILMPMLHTSKQQSMMFRPISQCLFWVLVADLLTLTWIGGQPVEHPYIIIGQLASVMYFLLILVLMPVASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YFBV_SALEP
Sequence: MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMTRYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAMB_SALSV
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQVTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVNQQNDWESTDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENIDLGFGKLSLAATRSTEAGGSYTFSSQNIYDEVKDTANDVFDVRLAGLQTNPDGVLELGVDYGRANTTDGYKLADGASKDGWMFTAEHTQSMLKGYNKFVVQYATDAMTTQGKGQARGSDGSSSFTEELPDGTKINYANKVINNNGDMWRILDHGAISLGDKWDLMYVGMYQNIDWDNNLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNVKSQQTGDRNNQYKITLAQQWQAGDSIWSRPAIRIFATYAKWDEKWGYIKDGDNISRYAAATNSGISTNSRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y1803_ACTSZ
Sequence: MAGHSKWANIKHRKAAQDAQRGKIFTKLIRELVTAAKIGGGDAGSNPRLRAAVDKALASNMTRDTINRAIDRGVGGGDDTNMETRVYEGYGPGGTAVMVECLSDNANRTISQVRPSFTKCGGNLGTEGSVGYLFNKKGLIIIDAGADEDALTEAAIEAGADDIQPQDDGSFEIYTAWEELGDVRDGIEKAGFKIAEAEVSMIPTTTVDLDAETAPKLLRLIDMLEDCDDVQNVYHNGEISDEVAALL
What are the official names of this protein?
Probable transcriptional regulatory protein Asuc_1803.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCN2_ANTMA
Sequence: MGSRHQVVQQQNRGDVVPGAIKQKSMAVEKKNRRALGDIGNVVTVRGVEGKALPQVSRPITRGFCAQLIANAEAAAAENNKNSLAVNAKGADGALPIKRAVARVPVQKKTVKSKPQEIIEISPDTEKKKAPVLEKEITGEKSLKKKAPTLTSTLTARSKAASVVRTKPKEQIVDIDAADVNNDLAVVEYVEDMYKFYKSAENDSRPHDYMDSQPEINEKMRAILIDWLVQVHYKFELSPETLYLTINIVDRYLASKTTSRRELQLLGMSSMLIASKYEEIWAPEVNDLVCISDGSYSNEQVLRMEKKILGALEWYLTVPTPYVFLVRFIKASLPDSDVEKNMVYFLAELGMMNYATIIMYCPSMIAAAAVYAARCTLNKMPIWNETLRMHTGFSEVQLMDCAKLLIDFHGGSTDQKLQGIYRKYSRLEKGAVALLPQPLLA
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RL7A_HALS3
Sequence: MPVYVDYDVPADLQERALESLEVARDTGSVKKGTNETTKAIERGNADIVFVAEDVSPEEIVMHLPELAAEKGIEVVFVETQDELGNAAGLEVGSAAAAVVAAGDAEDEIEDISTKVEDLQ
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_BRUME
Sequence: MASPKETLQRRAARVRRQVKAVANGRPRLSVHRSSKNIYAQIIDDVRGVTLAAASTLDGDLKGKLKTGADSAAAAAVGKLVAERAVKAGVKDVVFDRGAFIYHGRVKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL40_EIMBO
Sequence: MQIFVKTLTGKTITLDVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLALLASKYNCEKKICRKCYARLPPRATNCRKKKCGHTSQLRPKKKPKN
What is the function of this protein?
Component of the 60S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-60S ribosomal protein L40, Ubiquitin A-52 residue ribosomal protein fusion product 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [60S ribosomal protein L40]: Cytoplasm.
Protein: FOXO1_XENLA
Sequence: MAEAPQPPPPLVEIDPDFEPFSRPRSCTWPLPRPEFNPSSSANSSPAPSLQPEPAAGNVDFLSNLSLLEESEDFDPAEALGVCGDFPCQDIRQLQPPIPQQQQQHSQQQQEALTLLAPSVPSALSPASSPSPLGAQQPRKSSSSRRNAWGNLSYADLISQAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFVRVQNEGTGKSSWWILNPEGGKNGKSPRRRAASMDNNSKFAKSRGRAAKKKASMQSSQDGSSDSPGSQFSKWPGSPSSQSNDDFEAWSTFRPRTSSNASTISGRLSPIMPEQDDLGDADVHNLVYPSSATKLTSTLPSLSEMGNSENMENLLDNLNLLTPNSSTQSSPASMMQQSGYLFTSPNTSLGSPNSEYRKYSYAQTGISPISQMPMQTVPENKSGYRAVGQYPVPAGLLKELLTSDSPPHNDILTPVDPAVSQANNRVLGQNSLIGSNSIMPAYGSQPAPNKMSSHPHLHQPNHPTSINGRPIAHNPGINRLSTVKTSVQVPMPHQPIQMTSMGSYSMNSCNGYGRVGIVSIHQEILPSDLDDMLIESLDCDVESIIRNDLMEDGEADFNFDSILPNQSFPHSVTTTTHSWVSG
What is the function of this protein?
Transcription factor that regulates metabolic homeostasis in response to oxidative stress.  Binds to the consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'.  Main regulator of redox balance and osteoblast numbers and controls bone mass.  Orchestrates the endocrine function of the skeleton in regulating glucose metabolism.  Also acts as a key regulator of chondrogenic commitment of skeletal progenitor cells in response to lipid availability: when lipids levels are low, translocates to the nucleus and promotes expression of sox9, which induces chondrogenic commitment and suppresses fatty acid oxidation.  Acts synergistically with atf4 to suppress osteocalcin/bglap activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity.  Also suppresses the transcriptional activity of runx2, an upstream activator of osteocalcin/bglap.
What are the official names of this protein?
Forkhead box protein O1, FoxO1, xFoxO1, FoxO1A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and nucleus.
Protein: RL24_LATSS
Sequence: MFVKTGDKVKVISGKDKGKEGTIIKAMPKEGRVVVEGINTIKKHVKPNAQNPNGGIVDTEASIDASNVMLIDPSNNEATRVGYKVVDGKKVRVSKKTGESIDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RECR_HELMI
Sequence: MRYYAEPVGRLIEELSKLPGVGPKTAQRLAFHLLHVPRNEAVALAKAIVEAHDKTLYCSVCTNLTDRDPCRICSDANRDRAVICVVEEPRDVVAVEKTREYRGHYHVLHGALSPIEGVGPEQLRISQLMARLADPELKEVIVATNPTVEGEATAAYLARLIKPMGVKVTRIAHGLPVGGDLEYADQVTLLRAMEGRREL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: OR5T1_HUMAN
Sequence: MSGLPSDMDLYKLQLNNFTEVTMFILISFTEEFDVQVFLFLLFLAIYLFTLIGNLGLVVPIIGDFWLHSPMYYFLGVLSFLDVCYSTVVTPKMLVNFLAKNKSISFLGCATQMFLACTFGTTECFLLAAMAYDRYVAIYNPLLYSVSMSPRVYVPLITASYVASILHATIHTVATFSLSFCGSNEIRHVFCNMPPLLAISCSDTHVIQLLFFYFVGSIEIVTILIVLISYGFILLAILKMQSAEGRRKVFSTCGAHLTGVTIYHGTILFMYVRPSSSYTSDNDMIVSIFYTIVIPMLNPIIYSLRNKDVKEAIKRLLVRNWFINKL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5T1, Olfactory receptor OR11-179.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURG_COXB1
Sequence: MNRILIIAGGTGGHIFPALAVARELREQEVDVQWLGVKGGLEEKLVPDSFPLHLIQIKAFRGKRGLQQLLMPLRLVRAVFQAYRIIRQFKPDVILGMGGYVAGPGGLAAWITRTPLIIHEQNSIPGLTNRVLAKMAKFILQGFPDTFPQNRKVITTGNPVRTELVKMPLPQVRLAARRGPLRILVLGGSQGARSINQKMLAALSSYPRSEEIAVWHQTGQRDFEFIQKEYEKIKIEAKVDNFISDMAGAYGWADLVVCRAGALTVCEIASVGVASIFIPYPHAVDNHQFHNARFLEQAGAAIIISEESLTETDLMRWFEQFAQDRDRLLTMAENARKLAKPEAVQRVIAQCKKFYAAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CETZ2_HALVD
Sequence: MKTVLIGVGQAGGKLASALQSFDRQTGFGAVLDAVAVNTAKADLQSLPVETVLIGQDRVNGHGVGGDNELGAAVMESDQTEVMSALDGRVTAEAESIFVVAGLGGGSGSGGAPVLAKALAGVYDVPVYVLGILPGADEGALYQVNAGRSLKTVAREADAVLLVDNDAFRSAGESMSEGYDAINEAIARRVGLLLAAGEATEGVGESVVDTSEVINTLRSGGIAALGYASAEASPNAEDNINAVMSTTRRAVLTGTSLPDASDADAALVVIAGEPDTIPRKGVERARRWVEDETGSMQVRGGDFPLESGRLASLVLLGGVERSERVESFMERAREAIDKAETEPREDPKGMWHSDDLDDLL
What is the function of this protein?
Involved in cell shape control.
What are the official names of this protein?
Tubulin-like protein CetZ2, Cell-structure-related euryarchaeota tubulin/FtsZ homolog 2.
What is the protein family that this protein belongs to?
Belongs to the CetZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_LEPCA
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNFLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDVLGFLILILLLTLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPLLHMSKQRSMMFRPISQVLFWILVADLLTLTWIGGQPVEHPFITIGQVASILYFSIILIFMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1250_HAEIN
Sequence: MFNLKREHFRDDYLYRFYQYGDTHSKIPSNLYKVLARKLDMISASENINDLRSPPANHLELLEPKENKIYSIRVNKQYCLIFKYENNEVNNLYLDPHSYNL
What are the official names of this protein?
Uncharacterized protein HI_1250.
Protein: MPIP1_MOUSE
Sequence: MELGPEPPHRRRLFFACSPTPAPQPTGKMLFGASAAGGLSPVTNLTVTMDQLEGLGSDCEKMEVRNNSSLQRMGSSESTDSGFCLDSPGPLDSKENLEISLTRINSLPQKLLGCSPALKRSHSDSLDHDTFHLIDQDENKENEAFEFKKPIRPASRHIYEESKDPFTHRQNSAPARMLSSNESESGNFSPLFIPQSPVKATLSDEDDGFIDLLDGENMKNDEETPSCMASLWTAPLVMRRPANLADRCGLFDSPSPCGSSTRAVLKRADRSHEEPPRGTKRRKSVPSPVKAKADVPEPAQLPSQSLSLMSSPKGTIENILDSDPRDLIGDFSKGYLFNTVSGKHQDLKYISPEIMASVLNGKFAGLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKNPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
What is the function of this protein?
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.  Directly dephosphorylates CDK1 and stimulates its kinase activity.  Also dephosphorylates CDK2 in complex with cyclin E, in vitro (By similarity).  Phosphorylation by PIM1 leads to an increase in phosphatase activity (By similarity).
What are the official names of this protein?
M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
Protein: PYRB_ALISL
Sequence: MANSLYQKHIISIPELSREELELIVETAGNIKKEPQPDLLKNKVIASCFFEASTRTRLSFETAIQRLGGSVIGFDSAGNTSLAQKGETLADSVQIIASYANAYVMRHPREGAARLASEFSNGTPVINAGDGANQHPTQTLLDLYTIYETQGRLDNLNIAFVGDLKYGRTVHSLTQALAKFNGVKFFFIAPEVLAMPDYICEELDELGIEYQLLNSMEEAIPELDILYMTRVQKERFDESEYAHIKSAYILSAADLKPARENLKVLHPLPRIDEINIDVDKTPHAYYFQQAENGVYARQALLALVLNESL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PQQE_XANCP
Sequence: MSTVPPPLSVLLELTHRCPLACPYCSNPIALAALREEMDTAGWRSLLEQAAEMGVLQAHFSGGEPMLRKDLPELVAHARALGLYSNLITSGVAGGEPMLDQLQAAGLEHVQLSVQDVDPAGADHIAGYRNSLSKKRAFAAAVRARGLPLTLNAVIHRHNAERVPGMIALALEWGAERIEVAHTQYYGWGLRNRAALMPSREQLAATIVAVETARRSLGDQLAIDFVTPDYYARQPKPCMGGWAQRFVNISPRGDVLPCHAAETIDGLQFDNLRDRSLADIWNHGEAFARFRGTAWMPEVCQGCPKREIDWGGCRCQALALAGDAATLDPVCERSPAHAGIRATAEREAASPAPDFVYRRPERPAAVAAEAAISDTE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: FER1_PHYAN
Sequence: ATYKVTLVTPSGTQTIDCPDDTYVLDAAEEAGLDLPYSCRAGSCSSCAGKVTAGTVDQEDQSFLDDDQIEAGFVLTCVAYPKGDVTIETHKEEDIA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-1, Ferredoxin I.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYP_NOVAD
Sequence: MNQPAIKHALNVKRADDFAQWYQAVIAEAELAEESGVRGCMVIKPWGYGIWERIQKLMDAEIKEAGVENCYFPLFIPLSYFTKEAEHVEGFAKEMAVVTHHRLISDGKGGLTPDPEAKLEEPLVVRPTSETVIGAAMSRWIQSWRDLPLLTNQWANVVRWEMRTRMFLRTSEFLWQEGHTAHVDEADAMKETLRALEMYRAFAEGPLAMPVIAGPKPENERFPGAVETFSIEAMMQDGKALQAGTSHYLGTTFAKAAGIQYQNKEGQQALAHTTSWGVSTRLIGGVIMTHGDDDGLRVPPQVAPQQIVILPMLRDNEGDDALLAYCEEIRASLVKLSVFGERIRVLLDKRPGKATQKRWAWVKKGMPLILEIGGRDAEGGLVSVLRRDRLWRQDAKPNFVGQAKDDFLASAATELESIQAALYDEARARRDAQIVRDVTDLEGLKGYFAEGNKYPGWVEMGWAKPTGEALDKVVEQLKALKLTIRNTPMDAEKPVGACPFTGEPAVEKILIARSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_VIBCH
Sequence: MSTQFDSAPFLKTVTNQPGVYRMYNAEAEVIYVGKAKDLKKRLTSYFRKNLDSEKTKALVSNIAKIDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYIFLSAHKHPRLSSHRGAKKRRGEYFGPYPDSGAVRETLHLIQKIFPVRQCEDTVYSNRTRPCLMYQIGRCAGPCVKGLISDQGYQEIVHYLRLFLQGKDNQVLSILVEKMEQASRELRFEDAAKARDQIQAIRRVQEQQFVSDDSLEDLDVLGFAQENGIACIHILMIRQGKVLGSRSHFPKIPSDTSQVEVFESFLSQYYLSHSEARSIPARIILNRGLTEETEALQIAISELAGRKVTFHVNPTGTRGRYLKLANTNALTAITTKMNHKMTISQRFKALQEELGMDAITRMECFDISHTMGESTMASCVVFNQEGPLKQEYRRYNITGITGGDDYAAMAQVLERRYSKQLDSSKIPDIIFIDGGKGQLNRAYEIISSCWQDWPKYPKIIGIAKGVTRKPGLETLITIDGDEFHLPSDAPALHLIQHIRDESHNHAIAGHRAQRGKTRRTSTLEGIEGVGPKRRQALLKYLGGMQELKRASVEEIAKVPGISHALAENIYQALKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLE2_BACCZ
Sequence: MFKENTIKLGIAPIAWTNDDMPELGAENTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLELRNLEIASAWFSAFLTTKPLEETVQAFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWEKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDMTDPELVSLLFDTGHLVFSGEEPLYILKKYLSRIKHVHLKDIRQEVVDAVKESDLSFLQAVKNGAFTVPGDGVIVFDEVFTILANSDYKGWFVVEAEQDPALANPFEYALKARKFIQEKAGL
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase 2, 2-keto-myo-inositol dehydratase 2, 2KMI dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.