PharMolix/UniProtQA huggingface dataset:
Protein: H8C01_CYRHA
Sequence: TFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVRSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1k, U3-TRTX-Hhn1k, Hainantoxin-VIII-3, HNTX-VIII-3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_CHESB
Sequence: MAEKKKGKTITVEQIGSPIRRPKEQRATLVGLGLNKLHRRSTLEDTPSVRGMIAKVEHLVRVVDEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: COBS_SHEDO
Sequence: MSNEYNWLRQLNLFFVATGFFTRLPTPSWVIADDNELKKSSRYFGLVGLLIGLICALVYWFTQQWLPTSVAVLLAMVAGVLVTGGFHEDGLADTADGFLGGKTFEDKLRIMKDNHLGSYGAIVLALILLLRWQLLVELALFSPWAAITGFIVAHTLSRVLAASLIFSVKYVTDLELEEGKRLSHDQSLNDLFILLASGIFVLFWLNGLAAFVLFISLWALRFCLCKYFRSQIGGYTGDTLDAAQQVSEIMCYLIILAVGLSA
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL2_HPV31
Sequence: MRSKRSTKRTKRASATQLYQTCKAAGTCPSDVIPKIEHTTIADQILRYGSMGVFFGGLGIGSGSGTGGRTGYVPLSTRPSTVSEASIPIRPPVSIDPVGPLDPSIVSLVEESGIVDVGAPAPIPHPPTTSGFDIATTADTTPAILDVTSVSTHENPTFTDPSVLQPPTPAETSGHLLLSSSSISTHNYEEIPMDTFIVSTNNENITSSTPIPGVRRPARLGLYSKATQQVKVIDPTFLSAPKQLITYENPAYETVNAEESLYFSNTSHNIAPDPDFLDIIALHRPALTSRRNTVRYSRLGNKQTLRTRSGATIGARVHYYYDISSINPAGESIEMQPLGASATTTSTLNDGLYDIYADTDFTVDTPATHNVSPSTAVQSTSAVSAYVPTNTTVPLSTGFDIPIFSGPDVPIEHAPTQVFPFPLAPTTPQVSIFVDGGDFYLHPSYYMLKRRRKRVSYFFTDVSVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: PLSY_CROS5
Sequence: MAFLISALLILIGYLLGSIPTGYLTGLHLKGIDVRQHGSGSTGATNILRTIGKRAAIFVLTVDLAKAMLAVILVKLWFFVESPEMIPLEWKSWLVVFAAIAAVLGHSKSIFLNFTGGKSVASSLGVLLVLNPIVALGTLGSFLAMLSLSRIVSLSSITGVVAVNVLMFGLHQPLPYCLFGVIVGLYVTFRHRTNIIRLLQGTEPRLGQKLQQEGS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISX_MYCTO
Sequence: MTAPPPVLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: EIF3I_DROSI
Sequence: MRPLMLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESRKLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQSCELFLIDVRNADSSLSEQEPTLRIPMTESKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGTDHSAGINDMQLSKDGTMFVTASRDTTAKLFDSESLMCLKTYKTERPVNSAAISPIMDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDSTYFENIFE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, TRIP-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF18_CYACA
Sequence: MQSLTLEQEFKLKVYKENLKKLTLKQSQKHLVEVLKQMMLKDNIIKYLIRNSYF
What are the official names of this protein?
Uncharacterized protein ycf18.
What is the protein family that this protein belongs to?
Belongs to the ycf18/nblA family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KGX18_CENEL
Sequence: DRDSCIDKSRCSKYGYYQECQDCCKKAGHNGGTCMFFKCKCA
What is the function of this protein?
Blocks in a reversible manner human and rat Kv11. 1/KCNH2/ERG1 potassium channels (PubMed:18338253).  Also completely and irreversibly blocks rat Kv11. 2/KCNH6/ERG2 and human Kv11. 3/KCNH7/ERG3 channels (PubMed:18338253).  Also weakly inhibits Kir2. 1/KCNJ2 and Kv1. 2/KCNA2 potassium channels (PubMed:29483648).
What are the official names of this protein?
Potassium channel toxin gamma-KTx 1.8, CeErgTx5, CeErg5.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_STRGG
Sequence: MAVKIKLKRLGKIRSPHYRIVVADSRTRRDGRAIEEIGLYHPVQNPSRIEVNSERAQYWLSVGAQPTEPVLAILKLTGDWQAHKGLPAPAPLLQPEPKADKRALFEALSSDGDEAKGEAITPKAKKSDKKADEAAEASASTESTEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PMGT1_HUMAN
Sequence: MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
What is the function of this protein?
Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins (PubMed:11709191, PubMed:27493216, PubMed:28512129).  Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties (PubMed:11709191, PubMed:27493216).  Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
What are the official names of this protein?
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2, GnT I.2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: CRTE_CYAPA
Sequence: MKPLQTNFNLLTYLYERKEIVEDTLNKSIPRGNPTFIYDSIRYSLSAGGKRIRPILCLASCELAGGTMEMALPTACALEMIHTMSLIHDDLPAMDNDSYRRGKPTNHIIYGEDLAILAGDALLAYAFEFIATQTKNVPADLIVKVIAQVAHSVTTSGLVGGQIIDLSSEGKSDTTLETLNFIHIHKTGALLEAAVLSGALLAGAKEKDMNRFLRYAQNIGLAFQIIDDVLDIISTEEKLGKSIGKDLKTQKATYPSFWGVEESIKQAELLVEEAKEEILYFDNKAIPLIAIADFIVNRNN
What is the function of this protein?
Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes.
What are the official names of this protein?
Geranylgeranyl diphosphate synthase, GGPP synthase, Farnesyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: T178B_HUMAN
Sequence: MAAGRLLLYTGLSLALCALGMLAVAICSDHWYETDARKHRDRCKAFNTRRVDPGFIYNNNNNLPLRASRSRLDRWEGKLLRARNRRQLFAMSPADECSRQYNSTNMGLWRKCHRQGFDPEIAALIRKGEIERCTYIKYHYSSATIPRNLTFNITKTIRQDEWHALHLRRMTAGFMGMAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGGTFCIISLCTCVAGINFELSRYPRYLYGLPDDISHGYGWSMFCAWGGLGLTLISGFFCTLAPSVQPVPRTNYPKSRPENGTVC
What are the official names of this protein?
Transmembrane protein 178B.
What is the protein family that this protein belongs to?
Belongs to the TMEM178 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STB5L_MOUSE
Sequence: MKKFNFRKVLDGLTASSPGSGSSSGSNSGGAGSGSVHPGGTAGLPREEIQESLTSDYFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPVSGGAWNLGAQTYPEIIITGHADGTIKFWDASAMTLQMLYKLKTSKVFEKQKAGEGKQTCELVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEVTTEIVSLEVRLQCDVEDIITPEPETSPPFPDLSSQLPPSRSLSGSTNTVSSEGVTKDSIPCLSVKTRPVRMPPGYQADLVIQLVWVDGEPPQQITSLSISSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNRQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEISLPVTTEETRENSYNRSRSSSISSIDKDSKEAITALYFMESFARKNDSTVSPCLFVGTSLGMVVLISLNLPSSDEQRFTEPVVVLPSGTFLSLKGAVLTFSCMDRTGSLMQPPYEVWRDPNNTDENEKTWKRKLVMNYSSSSQEMGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF
What is the function of this protein?
Plays a role in vesicle trafficking and exocytosis inhibition (PubMed:25002582).  In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane (PubMed:21998599).  Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (PubMed:24744148).  Promotes as well axonal outgrowth (By similarity).
What are the official names of this protein?
Syntaxin-binding protein 5-like, Lethal(2) giant larvae protein homolog 4, Tomosyn-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane.
Protein: LPOA_SODGM
Sequence: MLYSYVLVFKTGRLLPVVLASLILAACTAQGPESQTGHAAIPANANADYYLQQMQQSSNDTKTDYQLLAIRALIKEGRLPQAQQQLAALQQIDSASLDAPQRLRYTQAMINAGQSRPSLDLVRAYIAQAPLLTDPAARQQNIDKTWQTLVSLPSPQSNLVINADENILQGWLDLLRIYQDNRQDPTLLQAAIKDWQTRYPQNPAAKTLPTPLSQVQNYSSSSVGGIALLLPLNGQAQVFSNAIQQGFSAAKNGLTTQQSALEQDASAAGQSTDGVPQNDGTAGTEPAGGSANQNGPVTTPGTRPDPAASGVDGQASAADNAPQATTLSGQSAGGQPSAAPSAASGVPVKVYDTSSQPLPALLAQAQRDGASMIIGPLLKNDVEQLYNDNAVAASAGTLNILALNQPEHLQPRPNICYFALSPEDEARDAANHIHQQGRQQPLLLLPRGALGDRIAKAFSDAWHQAGGATVLEQRFGSSAELKQNINSGSGISLTGTPVAAGAAVTIAGLTIPVPQDNGAVSPSGGAIDAVYIIATPVELALIKPMIDMRVSSRSRLALYASSRSYQADAGPDYSLEMEGLEFSDIPLLTGAHPALLSQISAQFRGDYSLVRLYAMGIDAWALANHFSEMRQIPGFQVAGETGTLSATPDCVINRTLSWLKYQRGQMIAAQ
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: ENO_THEGJ
Sequence: MENPFEITAVVAREILDSRGNPTVEVEVYTPVSMGRAAVPSGASTGTHEALELRDGGKRFHGKGVRRAVENVNKIIAPEIIGMDVTWQRDIDMLMIELDGTENKSNLGANAILGVSLAVAKAAANALGLPLYQYIGGTNAYVMPVPMSNVINGGVHAGNELDFQEFMIMPVGAKSFREGIRWVSETYHTLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLEVLIKAIEEAGYKPGDEIAFALDAASSEFYDEKLGKYVVGGKEYDRGELLELYRELVSKYPIVSIEDPFHEEDWEGFVMITRELGGKIQIVGDDLFVTNPKRIRKGIEMGAANALLLKVNQIGTLSEAIDAAYTAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGIAVYPGKRFRNPFL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RS18_FRATW
Sequence: MSRRKVCRFTVEGVKEIDYKDVNKLKAYITETGKIVPSRVTGTSAKYQRQLATAIKRARFLALLPYCDRHFN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CYDB_ECO57
Sequence: MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPVGFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGNFFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALAGVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLPLLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQLTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY
What is the function of this protein?
A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane.  It is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at low aeration.  Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron.
What are the official names of this protein?
Cytochrome bd-I ubiquinol oxidase subunit 2, Cytochrome bd-I oxidase subunit II, Cytochrome d ubiquinol oxidase subunit II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y201_ENCCU
Sequence: MEQRQLPCNHPNPTPRLRTSVPAIPPLHPQLSSLATSHPWIQKPSHLKGSPYLLSISSLCPLATSSCALLVHSQHPPRPSELSPPLSCFLCQKETLTSPRPSPPSHHCPESLTYQVHQPNPKSPSGPLVHSNRFKASERRRPNPPTSSLKLSCHILLSGIWRSNGFITMKDKRNNNTPVSNPEAPSSDSLSHSTPNSSNLQEKALSRPSLTSFPSSVSSI
What are the official names of this protein?
Uncharacterized protein ECU02_0010/ECU04_1710.
Protein: KTU_DROMO
Sequence: MSASTRNKHSKIHGNEKLDISNDEFDRIRDALKNEEFRKLFFDYVDEIQDPENRKIYEEEITQLEKERGVDVTFIHPQPGFVIKTSIDGELKCFINIASCKVVERPNNEVSVNSQTGQKGLSWSIPLAQIPPRDDLDANNKLCKVYDVVFHPDALHLAKRNAQFRQCLIDTALDGVEREYHVNLDRANLKFPKLDYKGMARPSVLRTLSKNPTAEEKEPHPLEHMYPKKPEADAGQSKVLPMKTKVTAVPKFAVPKYCIKHSHDVDMAEYTDELDAKLQVTVPRALVVEIELPLLSSTADCHLDVTEKSVYLLSEKQGAKYKLKVDLPYTVNDKAGNARFDTDHRCLRITLPVVRSTPREERNLHDTVRNLSREDSGVELNSNGESPVEDEELVVELSEHNQENDSNAFPPTAVVSPRSFLKSNLHYLLPAQFNCNILDNVIVFVLHVTNVQPDSVQTLQQARSLHLQFASMGTGYYPTHYAFLMQLPDGVQPELRIDQVEVDTGDENVVLRLTMNEHCMLLPSYLAGTDSNDLKEYPVFGHQNNNNEKETEVEVAEMEKCDLVSEKSLQINMDHNDVEHALEVTIEPQENEAPLDSLELLHEHQQELQQLHHQKKLNKKQRKRNKKQRSLSESACEDLKLAQEHHEQPMDTLKLPHRKQRSYSECNESSLGSSCVQRGILKRFSRYGPHPSISDSCSSIDDCSSTYSCSVDAAGTGFSQSFGSIPEERGGDEAGLSESCKKTVRFNDHIMKQVFRLDSSILGQRKKNQKRRDCKLRAQQRRLSEGDSADYVEVDSTHGSGDQPAHKTAANAQYFKQHNNNHPHVKDNKKQSLHDSGLDLTNGSINNKNNHSNENATKRNEADAKNTMMFEMDDVDEEAQDAANI
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog, PP1-interacting protein 20.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_PITOR
Sequence: GLWSTIKQKGKEAAIAAAKAAGQAALGAL
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria S. aureus (MIC=5. 7 uM), S. dysgalactiae (MIC=5. 7 uM), Nocardia sp (MIC=22. 9 uM) and S. uberis (MIC=5. 7 uM), and the Gram-negative bacteria P. aeruginosa, E. coli and A. calcoaceticus.  Has antiprotozoal activity against T. cruzi.  Has antifungal activity against the yeasts C. tropicalis (MIC=0. 37 uM), C. guilliermondii (MIC=22. 9 uM), C. albicans (MIC=5. 7 uM) and C. albicans ATCC 1023 (MIC=5. 7 uM).  Lacks hemolytic activity against human and murine erythrocytes.  Does not cause morphological changes in murine liver, spleen and kidney.  Decreases viability of murine peritoneal cells.  Fuses to, and disrupts liposomes.
What are the official names of this protein?
Dermaseptin-O1, DRS-O1, Dermaseptin-01, DS 01.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_RUEPO
Sequence: MTSGKNGITYAEAGVDIDAGNALVDRIKPAAKRTNRPGVASGLGGFGALFDLKAAGYQDPVLVAATDGVGTKLRIAIDTGLVDGVGIDLVAMCVNDLVCQGAEPLFFLDYFATGKLETDTAARIIEGIAEGCVQSGCALIGGETAEMPGMYPAGDFDLAGFAVGAMERGTALPEGVVEGDVLLGLASNGVHSNGYSLVRKLVEISGNTWESDCPFGDGKLGQALLTPTRLYVRQVLAAIRAGGVHALAHITGGGLTENLPRVLPEGMGATIDLDTWDLPPVFGWMAETGGIAEAEMLKTFNCGIGMIVVCAADRAEALAELLSAEGETVARIGTVTTTPGIAYTGKLL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHB_STRAW
Sequence: MKDLPDRRLLLVHAHPDDESINNGATMARYAAEGAQVTLVTCTLGEEGEVIPPALAHLTPDRDDALGPYRVGELAAAMKELGVTDHRFLGGPGRYRDSGMMGGEQNHRAGAFWAADLDEAAGHLVAVVREVRPQVLVTYDPDGGYGHPDHIQAHRVAVRAAELAADPAFRPELGTPWEIAKVYWNRVPRPVAEEGFARLRLALPGTRFAKSAAVDDVPGVVDESVITTEIDGTPFAAAKAAAMRAHATQVEVDGPWFALSNELAQPLFTTEYYELVRGERGSPRETDLFEGVAP
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: YGIB_SHIBS
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLASCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESIAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: TSAD_CHRSD
Sequence: MRVLGIETSCDETGVAIYDTERGLIADALHSQMAMHAEFGGVVPELASRDHTRKLLPLIRQVLDDAELRGDQLDAIAYTAGPGLVGALMVGASTAHGLARAWDIPALGVHHMEGHLLAPMLEAAPPDFPFVALLVSGGHTQLVEVHGLGRYRLLGESVDDAAGEAFDKAAKMLELPYPGGPHVAQLAERGDPTRFRFPRPMTDRPGLDFSFSGLKTHTLTTANQLKAAGPLSDQDRADIARAFEEAVVDTLVIKCRRALDTTGLKRLVVAGGVSANHRLRERLDRETAKRQAQAFYPRGRFCTDNGAMIAYVGAQRLLAGERDDATMQATPRWPLASLTPPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PETMO
Sequence: MHLKAFGKVNLYLDVISRRKDNYHNILTLFQSINEHDDIFIEFSESEIFESEPPLNISWDNNIIKKSIETFKKETGFDNFNLKIKLIKNLPMGGGLGGGSADAAAVLNFLSKNFKISEKDLFEISCKIGSDVPFLLKGGTAIGKGKGEILEFLEPLKLNIQIYPMNYNIDTKKMYEKLDQNWKSINHFGDPYNLYEALKNNDIITAKQNAFNVFEQVAFKEYPKLKQKKEDMEKDEGIIFALMSGSGSTLYKVIYAN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.