PharMolix/UniProtQA huggingface dataset:
Protein: FAB1_SCHPO
Sequence: MSEVETPTAASPTFPVETSHRLDTLHTSSTEQIIKDSENVVHTTLKLPTSTLSREFWMKDERTNNCSLCETEFTLFRRKHHCRICGKIICKYCLKEAPGFIFRLQGSIKVCRPCASILVNNYSRSQLFNHSLNESKNRDLTEQHPFVTLDELNSNDQVLSSFGDLSSTFEMPNNIHPPEVAPMIAIPSSRSNYDSPGWAHHSIFLDWSKRNLDSNVINVEDSESGKYNALTITNSYDAGPSSVSTDYRPVNFGKVPSYSKLRKNKAFSSAKVSDMYLSADERNRLEDFSKGDRGLSFVNLSPNIKATSYDRLSTVINEPFISRSSSLTDERGLADSGNSYHHFSDSDDESLFNDGLGLSFHANSAIIKQRQQNVASIQRYGNESYLSNFLKAFLPKTVCDYLFPSSTIPDGLPALIENFNARVDKVNHPGGTEEPLPYQGKSRASSVVTSSKSTCILPPWILFSDSFNQLVCTFLGKLLFQMLNDEGVDSPMQWVLCLPKILLKMALDLGPDIRSGDDIDVRSYVKIKKIPGGSIQDCFLVNGVLFSKKASSKSMDRSLRRPRIALLTFSLDYACDEQRILSLDLIISQQEEYIINLVNRICMLKPNLVFAQGQIPSIALKYFEEHGVIAFHGLKESVLYDIARCCRADIISSIDKLSLCPRLGTCGRFQLRTYVVDENKGLRKTFAILDRCSERLGCTIVLRGADYNQLSKVKKIVELVVLIAYHIKLECALLRDKFVNMPELFETTYQSLSRKSLPSFASTAADKEKSQNHEKKSLNSDNQSLRPLENENQSVSSTQGSNSPLELINNLPASDDYSSITKALKTRFLTFSPFLSKPLPRLLNQVNYYQFIRNKLLKDVKLHPYSPTGSFVMKQSENDNVEESYEESYKFFCIDERYHFLEKQWTLYYSHSKLMFSPFSSQRIILLYSIINKETSVPCIGPERCLLEFYRETDCTLGQYIEDSCLNTNVSCGGEYCKTNDMLWHYRSYVHGNSRISVFLESFSCPVPGLEEKIIMWSYCKFCKKNTHITVMSEETWKYSFGKYLEFMFYNSQIRDRFEFCDHSVMAQHVHYFGYCNMALRFQRDLIEIFELFVPSVTLRNNPSYIKELKEKEYKRLKGVIEKCLSSVASRINQIKCDWVTDPEKFESCTSEISKFRTLLSSDYTELYSEFDSIYLNSSTSDYLSLNSILRVLQGKMVKWEQRFLDYQRLYLPSYKELSKIAAAQIKKVFLERPLSQTPLDLPETLENTQIDIYPSFKTESTDDQLEKVTQTNVASNKRVAPYADSMANVGSPESDCFSVATSSDIPKANIDFTNDISTQNTFPASPVSNSGFSRQTYPNISQRQGVNMLSHKRKSASTSDRRFVNASSTSGMNMPISSSISAKISSIQNSTKYSPRKPIPAKDVRVSSLVRRFEELSLQLQEKQKRDEELIKARRKRALPVVPSKPVVEVFNDLNEAFDDENSEDENGINDTKENRATESNFSGVDSMSKERENVSSNEDNSPEAFEDIFGILFKNESGLEEQQNLEPSSQMDKEGSKLPTSGPLADKTSVYRILSAFWNEWNSLNPPPFEFPLQPTEHMFSDSNVIIREDEPSSLISFTLSSPDYLSKMVEIEDSMDEALTNQGLQGSTQFKIENLMLKPTGTHLKYQFEEGSARLSCKVFFAEQFSALRRACGCEETFVTSLARCSLWESSGGKSGSAFLKTFDKKYILKVLSRLESDSLLNFAPAYFDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTICKTDIMIMENVFYDECPSRIFDLKGSMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQLKSLLHSCLWNDTLFLSKLNIMDYSLIVGIDYTKKELYVGIIDFIRTYTWDKKLESWVKEKGLVGRGPEPTIVTPKQYKNRFRKAMDCYILASQDFETGEGFKFCE
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate.  Required for endocytic-vacuolar pathway and nuclear migration.  The product of the reaction, PI(3,5)P2 is an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole.  PI(3,5)P2 regulates the transition between trans-SNARE complex formation and vacuole membrane fusion (By similarity).  Required for survival under conditions of nitrogen starvation.  May have a role in the secretion of pheromone peptides (PubMed:11895483).
What are the official names of this protein?
1-phosphatidylinositol 3-phosphate 5-kinase fab1, Phosphatidylinositol 3-phosphate 5-kinase, Diphosphoinositide kinase, Type III PIP kinase, PIPkin-III.
What are the subcellular locations of this protein?
Cytoplasm. Note=During cell fusion of opposite mating types, migrates to the isthmus.
Protein: RL16_YERPS
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGEFGLKACGRCRLTARQIEAARRAMTRAIKRQGKVWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLFEMAGVPEETAREAFKLAAAKLPVGTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YNDF_BACSU
Sequence: MKSKLKRQLPAMVIVCLLMICVTGCWSSREIEDLGLTFAIAIDKGKETNTEKELKEEGGSYPKKDNITLTYQFVNEKAAGAGTSGGGGSGQGAQKAYINISETGDSLQQIGSEVALRRDREVFSPHLKVVVMSEDVLHTFPIDEMLDQFFRDNEIRLSCLVLSAKGEARDALQLKENGEIPAFRLIGLGENEHKVSRILPPMTLAKLIGKLHSGSSFLLQNVVAANGAVKYSGAAVINGKSKKMIGTLNEYETEGITWIRGEGKGGVVKSHDKKSQQTLAYDINKIKSRIQPIVKGKDISFHVDIESEGDLVENWNTKEALDTQFIDRLETTIENEVKKIVGQVLKKIQHDYKADVAGFDESFRLTYPHLWKRVKNNWDDTFSKADITYSVNVTITHFGTVKTQ
What is the function of this protein?
May be involved in spore germination.
What are the official names of this protein?
Spore germination protein YndF.
What is the protein family that this protein belongs to?
Belongs to the GerABKC lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y130_MYCPN
Sequence: MKEKTPFKNEKEFHDMVKKTKKGTFSGWYIVNPENNSVEFSGNFNRQFKLNKPVIPVNTEYVTRKEFNEYKDSNDQRLIKIETTLAAQGEQIRIQGEQIKELQIEQKAQSETLKLILQTLQKMSDRLDKMDVRLDKLESK
What are the official names of this protein?
UPF0134 protein MPN_130.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: SL6_CROAD
Sequence: MGRLVFVSFGLLVVFLSLSGTGADCPSDWSSYEGHCYRVFQQEMTWEAAEKFCTQQHQKSHPVYFRSSEEVDFLVSILKFDLFWMGWRDIWNERRLQWSDGTKVNYKAWSAEPECVVCRATDNQWFSTSCSKTHNVICKF
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
C-type lectin 6.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPS_LEGPC
Sequence: MSRQNLEEIIQTGIADTELSTEISTAIKRPRKYKVLLLNDDYTPMDFVVEVLKHFFHLNEEVAIQVMLQVHFQGKGVCGVFTRDIAETKVALVNEYARMNQHPLLSSMEPE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: EFP_SHIDS
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDB1_PYRFU
Sequence: MDRVAKAREIIEKAKAENRPLVEPEAKEILKLYGIPVPEFKVARNEEEAVKFSGEIGYPVVMKIVSPQIIHKSDAGGVKINIKNDEEAREAFRTIMQNARNYKPDADLWGVIIYRMLPLGREVIVGMIRDPQFGPAVMFGLGGIFVEILKDVSFRVAPITKEDALEMIREIKAYPILAGARGEKPVNIEALADIIVKVGELALELPEIKEIDINPIFAYEDSAIAVDARMIL
What is the function of this protein?
Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate.  Can use other substrates such as isobutyryl-CoA, propionyl-CoA and butyryl-CoA, but not indoleacetyl-CoA, phenylacetyl-CoA or succinyl-CoA.  Seems to be involved primarily in the conversion of acetyl-CoA to acetate.  Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters.
What are the official names of this protein?
Acetate--CoA ligase [ADP-forming] I subunit beta, ADP-forming acetyl coenzyme A synthetase I subunit beta, ACS I subunit beta.
What is the protein family that this protein belongs to?
Belongs to the acetate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INK1A_DANRE
Sequence: MLCLQESGDCLRDQMRYMMRSLQDLKHLRRSCVAPPVGPPVRLRACKQLIAQRERRARLRISDASEASSYDSACCLSSSLEEEESASDPSAVSSPSSERSLEFDSGYSEASWQDEGVVLRRTKNIRVSSTACLRTNQLSNTRARPKSTSDACLESWTSFETASDPEDWTTSLLTRGRNRQPLVLGDNSFADLIHNWMDLPECPEQTELKHSSGRSFAKDFLVNIKRRIAGFSRSADGRRKSSDVTKLSKSIVPTKRLSCQIDVQHKMPFFYKSHTGLNELDTDYYQFSALMKSGSRTPIVCNDIIGYI
What is the function of this protein?
Inhibitor of the serine/threonine-protein kinase pak4/pak5 (By similarity).  Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity (By similarity).  Required for the proper migration of neural crest cells during embryonic development, probably by inhibiting pak4/pak5 (PubMed:17314132).
What are the official names of this protein?
PAK4-inhibitor inka1, Induced in neural crest by AP2-alpha protein 1, zinca1.
What is the protein family that this protein belongs to?
Belongs to the INKA family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LUTA1_BACAN
Sequence: MKVTLFVTCLVDMFETNVGKATVEVLERLGCEIEFPEAQVCCGQPAYNSGHVEAAKEAMKHMIETFEDAEYIVTPSGSCATMFHEYPHVFKDDPKWAKRAQKVADKTYEFTQFIVDVLKVTDVGASLPGIATIHKSCHMTRMLGVTEAPGILLSNVKGLTVRELPNVQNCCGFGGTFSVKMTPISEQMVDEKVDSAMETGADYLIGADCGCLLNIGGRIERLGKEIKVMHIAEVLNSRS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 1.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: SPT16_DROME
Sequence: MSSFVLDKEAFVRRVKRLYTEWRAPSIGHDDALRNLDCIMSIVGVEEDVMYSKSMALQLWLLGYELTDTISVFCSDAVYFLTSKKKIEFLKQTQNITEEGFPEINLLVRDRTDKDQGNFEKLIKALQNSKKGKRLGVFAKDAYPGEFSEAWKKSLTASKFEHVDISTIIAYLMCPKDESEINNIRKASLVSMDIFNKYLKDEIMDIIDSDRKVKHNKLSDGCEAAIGEKKYTSGLDPRLLDMAYPPIIQSGGAYSLKFSAVADKNPLHFGVIVCSLGARYKSYCSNISRTFLVNPTEAMQENYTFLVSVQEEILKLLVPGTKLCDVYEKTLDFVKKEKPSMVDNLPKSFGFAMGLEFRENSIVIGPKCQALLKKNMVFNLHVGISNLTNPEATDKEGKNYALFIGDTVLVGEQSPASVMTPSKKKIKNVGIFIKDDSDEEDVDDKKTAKEDQGTEILGRSKRNAVLESKLRNEINTEEKRKEHQRELAQQLNERAKDRLARQGNSKEVEKVRKNTVSYKSISQMPREPEVKELKLYVDKKYETVIMPVFGIQVPFHISTIKNISQSVEGEYTYLRINFFHPGATMGRNEGGLYPQPEATFVKEVTYRSSNVKEHGEVGAPSANLNNAFRLIKEVQKRFKTREAEEREKEDLVKQDTLILSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHSNGFRYISVRGDKVDILYNNIKSAFFQPCDGEMIILLHFHLKYAIMFGKKKHVDVQFYTEVGEITTDLGKHQHMHDRDDLAAEQAERELRHKLKTAFKSFCEKVETMTKSVVEFDTPFRELGFPGAPFRSTVTLQPTSGSLVNLTEWPPFVITLDDVELVHFERVQFHLRNFDMIFVFKEYNKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGVQSLNWQKIMKTITDDPEGFFEQGGWTFLDPESGSEGENETAESEEDEAYNPTDAESDEESDEDSEYSEASEDSEESDEDLGSDEESGKDWSDLEREAAEEDRNHDYAADDKPRNGKFDSKKHGKSSKHSPSKSSKDKYNSRDKHHSSSSSGNKSSSKDKDRKRSRDDSRDNGHKSKKSRH
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  The FACT complex is required for expression of Hox genes.
What are the official names of this protein?
FACT complex subunit spt16, Facilitates chromatin transcription complex subunit SPT16, dSPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: Y2772_THIDA
Sequence: MFGWAITFLVIAIAAGIFGFAGLAGTAAWIAKVLFVVGLAAVLIMLVMGRRPPTV
What are the official names of this protein?
UPF0391 membrane protein Tbd_2772.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROD_SALEP
Sequence: MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFTFRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRKMQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVADLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: CARA_PHANO
Sequence: MFSHLLKPAARSAGLLGHVNRRYLATVHTNTAREIPKPSRKPTPISLENATFTIKNGPIFSGKSFGAKANISGEAVFTTSLVGYPESMTDPSYRGQILVFTQPLIGNYGVPSSARDEHGLLRYFESPNIQASGIVVQDYALKHSHWTAVESLAQWCAREGVPAISGVDTREVVTYLREQGSSLARITVGEEYDADEDEAYIDPEAINLVRRVSTKAPFHVSSSLGDMHVALIDCGVKENILRSLVSRGASVTCFPFDYPIHKVAHHFDGVFISNGPGDPTHCTSTVYNLRKLFETSQLPVMGICMGHQLIALAAGAKTIKLKYGNRAHNIPALDLTTGKCHITSQNHGYAVDPTTLTSEWKEYFTNLNDQSNEGLIHASRPIFSAQFHPEAKGGPMDSSYLFDKYIQNVQRYKDHQSSFSEKSNKPSPLLVDLLSKERVGVHPAQPDFEMHVPGRVEQVDVGGPVAPPYQPITAAA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, CPS-A, Arginine-specific carbamoyl-phosphate synthetase, glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_LEGPA
Sequence: MQRKIKSYVLRAGRISNRQQQGLDLWLEDYELKFDSPTPWNFAKEFGRHDADTIVEIGFGMGTSLFAMAMNNPQCNYLGIEVHKAGVGSLVADLHEHQISNVRVVVHDAVEVLQTKIPENSLAGVQIFFPDPWHKKRHHKRRLIQSEFIQMLVKKIRPSGFIHCATDWEDYAEHILNVLSSESALFNQQKEGGYSPRPDSRPLTKFEQRGERLGHGVWDLVFIKNKEVTNDKACNSY
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: AROB_SALNS
Sequence: MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_METPE
Sequence: MILVDWQIMDRISRGQIKVEPFEPGLIQPNSLDIRLGDHFVWYVPGDRVIDPYDKESVTAEVEEMNANEVILYPGQFMLAETKEVLSLPDNVVASIEGKSSIARLGIELHQTGGWIDAGFIGSITLEMCNVNQRPVKMYAGMPIGQLVFYTTERAEQPYNLKQDAKYQGQRQATLSRYHENQRFIQ
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PSAI_AEGSP
Sequence: MTDLNLPSIFVPLVGLVFPAIAMTSLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EX7L_SHESM
Sequence: MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCAMFKGRNQSVSFKPVNGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKLAAQGLFAADTKRQLPKNIQRIGVITSPSGAAIRDVLHVLARRDPSIEVIIYPTQVQGESADLNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVDTTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQERRLSLLEHRLQRLDPKRTLQQFEQRFDEMQLRLEAALSNKLHGLSRRQQQLASRLEQQSPKHKLALETNRLSYLATRLQDAMQDTLNQSEQRVKYAAHQLETVSPLATLSRGYSITTDANHQVIDNAAQLSVGDKINTRLRHGQVQSTVTQITDES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORA_CORAY
Sequence: MKRTLGHALIIIGAALIVIAVLLPTFLVPRLRVIPLDTVSDTITEVRDGTLLDSSQLGKNEPTPNRKNDPRCKAETDEEKRDLPVHCFINDKTPMQSKRHVEIEEPADEKIATLQVGTTLLRDDRKEPKNLINAILDRITVDRSTAYPVDDPISSVAINAPQGGSDTKPPTFTRPGIQYQFPFGAQKKSYPYYDVQAMRNFEIDFVGEETQDGVKVYKYSMTIPPQNLYESLTEHFTRDGRKLTEADKSSLASMRLSFPAHKWGLEGDDDVELDRYYTNVRTVRVEPTSGVIVNGTEEMFMFYAKDDKEAEEIASKAGREKEAKEQNRTAMKYTAQWDEGSKGRQMDRAKEARKSLTIGGTVAPWILGILGLVPIVIGFRIRSKSA
What is the function of this protein?
Forms water-filled channels that favor the permeation of cations.
What are the official names of this protein?
Porin PorA.
What is the protein family that this protein belongs to?
Belongs to the PorA family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Due to the absence of corynemycolates in the cell envelope the nature of the permeability barrier this porin is part of remains unclear.
Protein: HEMH_RHOCA
Sequence: MTIANRILPHAPADHPPVPVPRVGVLLANLGTPDATDYWSMRRYLNEFLSDRRVIDYPIWKWQPLLQLIILSKRPFTSGNNYRSIWNEERDESPLMTITRDQVRKLRAAVETRYGAGNVVVDFCMRYGNPSTRDVLDDMLAQGCERILFLPLYPQYAGATSATANDQFFRALMQVKRQPAARTVPEYFARPSYIEALASSVERVYATLDTRPDVLVASYHGMPKRYHREGDPYHCQCQKTSRLLRERLGWGPDSIDTTFQSVFGTEEWLRPYTVEHVVQLAEAGKKNIAVISPAFSADCIETLEEINGEIREAFEHAGGESFTYVPCLNDDDLHIAALLEVVEENLAGWID
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3154_SHEPA
Sequence: MLDTKFDELMEFPASFPFKIVGDASDTLADRVVAVAQSLAPGDYAPTTKASSKGTYNSVTIRITVTSKEHIEKLYTQLAAIEGVKRVL
What are the official names of this protein?
UPF0250 protein Spea_3154.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: RPOB_NEOSM
Sequence: MSEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLEFVSCRMGEPKHDEYGCVERGITYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQEIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDNDKARSISGKLNYIARIIPYRGSWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVCFVPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLADDLVSTKGEVLLPHGTKLTKEHVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAMLSIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIRLNAKFNLSHDESLTVLTKEDIFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADFDTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAGFEVRDVHTTHYGRICATETPEGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVTYLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVFIPRSEVQFADVSAKQIVSVAASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVVQYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPAIQKGELALGRNLVVAFLSWRGYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPEEITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVTPKSSSPVTPEEKLLRAIFGEKAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLTNYIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRFVDRFDEINKTYEENFEKIRGDDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISRIVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLGWAAYNLGKKISKLLDEGNYSEVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVLAGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGGKSHFGGQRFGEMECWALQAYGATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPESFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RBFA_BART1
Sequence: MKNAGPSQRQLRVAEQVRHAVAHILQRGILLDDVLKDIVISVSEVRISPDLKIATCFVSPLSTLKNTSHTDVVNTLNKHSRFLRGEISHALRQMKYMPELRFRLDNSFDNFSKIDALLRSPEVARDLHHSDKDED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMN1_HUMAN
Sequence: MPRPRRVSQLLDLCLWCFMKNISRYLTDIKPLPPNIKDRLIKIMSMQGQITDSNISEILHPEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQLVGPNKLKQVTWTVY
What are the official names of this protein?
Protein AMN1 homolog.
What is the protein family that this protein belongs to?
Belongs to the AMN1 family.
Protein: MIAA_CHLFF
Sequence: MRAPEFQANAITSTGCDVCLDPQKSFAKLFKRTIILLAGPTGSGKTDVSLCLAPMVDGEIVSVDSMQVYRGMDIGTAKVSLEARQRIPHYLIDICHVQELFNAVDFYYQATQACQNILSRNKVPILVGGSGFYFHTFLSGPPEGPPADREFRDHLALYIQKNGLSLLYDNLCMKDPEYARTITKNDKNKIVRALEIIHLTGKKVSEHNWSMEAKEPREYNCRGWFLSSPRDLLRDNIQLRCRRMLEDNLIDEVHRLLEQGIRENPSASKAIGYREWIDFIDQGSPKEAYEDVKNKFIANTLYYIKKQRTWFKRYPMFRELPTLGLTAETIAEKIAEDYFLHG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YAJC_RICPR
Sequence: MSQHTQDNQINNNETIEIQETDTVPVETNSLQSGLTSLIPMILIFAVFYFLLLRPQEKRRKEREKLVSGVKKGEEVLINSGIYGIVTKVSENDNNIEIEIAKDVRIKAIKSAIVDITSRKREVAATQENNKKNKKVSCAKSS
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: WAPB_TROCA
Sequence: MSSGGLLLLLGLLTLWAELTPVSSQDRPKKPGLCPPRPQKPPCVRECKNDWRCPGEQKCCRYGCIYECRDPIFVK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Carwaprin-b.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.