PharMolix/UniProtQA huggingface dataset:
Protein: MAEA_HUMAN
Sequence: MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972).  MAEA is required for normal cell proliferation (PubMed:29911972).  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).  Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity).  Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (PubMed:9763581).  Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis.  Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).  May contribute to nuclear architecture and cells division events (Probable).
What are the official names of this protein?
E3 ubiquitin-protein transferase MAEA, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, Macrophage erythroblast attacher, P44EMLP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Detected in a nuclear, speckled- like pattern (PubMed:16510120). Localized with condensed chromatin at prophase; Detected in nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis (PubMed:16510120). Present in cytoplasm, nuclear matrix and at the cell surface in macrophages; predominantly nuclear in immature macrophages and predominantly detected at the cell surface in mature macrophages. Colocalizes with F-actin in macrophages (By similarity).
Protein: ALDR_ENCCU
Sequence: MICKTQKLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVRDDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKELSREDISAIDALNTGHRYVDPPGFGPEKFK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
What are the official names of this protein?
Aldose reductase, AR, Aldehyde reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATA2_CANAL
Sequence: MPYTFNFPKSQSSFKYSIKSLTNSRSFPMISIYVTPQSTPKFINNQSIDKMTVLSSFRSRNSFIIARSILSKLLRKNKADFKKVSKSVSLLWGSVDNSFKNYFEYLSILESQWHDKKSSNLNPISSTRTTSELNYIELCSSIYNQSRKHPRSVQGNKAKFRLYKNVSKKSNRKPRRLKNGFKVSRSTINCSYGIYTEDVFQ
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Transcriptional activator that induces the transcription of a-specific mating genes.
What are the official names of this protein?
Mating-type-like protein A2, MTLa2 protein.
What is the protein family that this protein belongs to?
Belongs to the MATA2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_ROSCS
Sequence: MAGEFYDSARIFVQAGDGGDGAATFRREKYVPRGGPDGGDGGRGGHVYLVADPGLNTLLPFRERTRFIAERGGNGGRSRKHGRNGRDVFIRVPVGTVARTVIDGETYSVDLDAPGLRLLAARGGRGGLGNVHFATSSYQVPRIAELGEPGERREIELELKLLADVGLIGFPNAGKSTLLSVISAARPKIAPYPFTTLQPNLGVVEVGEYSFVVADIPGLIEGAHRGVGLGFSFLRHIERTRLLIHIIDAAGVDGRDPVNDFSAINEELRLYQPALAQRPQVVALNKADLPEAQANLKRLRAAIPVSEQDLFVISAATREGVDALLQRVAERLREMPAPHRAPRDETLTWPVPEVDERLYTIERTGDGWRVRGRRIERLISMTNFAQPDAIMRIQRVLEASGIGAALQEAGIQNGDVLYIEQAAFDWEDGAITYRMPGVS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVX1_MOUSE
Sequence: MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGSSPTSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAAAAAAAGPCSCLACHSGPANGLAPRAAAAAAASDFTCASTSRSDSFLTFAPSVLSKASSVAALDQREEVPLTR
What is the function of this protein?
May play a role in the specification of neuronal cell types.  May play a role in the dorsoventral specification of mesodermal cell fate.
What are the official names of this protein?
Homeobox even-skipped homolog protein 1, EVX-1.
What is the protein family that this protein belongs to?
Belongs to the even-skipped homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_RHOPT
Sequence: MADAAAPDAASVRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEQKTYLQAIPYFDRLDYVAPMNQEHAFCLAVEKLLGIAVPRRAQLIRVLYAEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMMFYERASGSRMHAAYFRVGGVHQDLPPKLVDDIDAWCDAFPAVVNDLDRLLSDNRIFKQRNVDIGVVTLDQAWSWGFSGVMVRGSGAAWDLRKSQPYECYAELDFEVPIGKNGDCYDRYHIRMEEMRQSVRIMKQCIAKLRAPDGQGPVVVDDHKIFPPRRGEMKRSMEALIHHFKLYTEGFHVPAGEVYVAVEAPKGEFGVYLVSDGSNKPYKCKIRAPGFAHLQAMDFLSRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLO16_ORYSI
Sequence: MASKPGPLTQWPWNNLGNYKYALVAPSAAYSTYRFVTASSAAERDLLNFMVFPMLLLRLLYGQLWITVSRHQTARSKHKIVNKSLDFEQIDRERNWDDQIILTALVFYLVSATMPQAQVAPWWSTKGMVVTAVLHAGPVEFLYYWLHRALHHHWLYARYHSHHHASIVTEPITSVIHPFAEEVVYFVLLAIPILSTVATGTVSVVTANGYLVYIDFMNYLGHCNFELVPKCLFHVFPPLKYLLYTPSFHSLHHTQFRTNYSLFMPVYDYIYGTTDKSSDELYERTLQGRDEAAWRPDVVHLTHLTAPESVFHNRLGFAAVASNPLGAAASGHLLRAASAVASPLLSLFASTFRSEANRLDKLNIETWVIPRFTSHYTSKSDGYKVSRLIEKAVSDAEASGARVLTLGLLNQGYDLNRNGELYVVRKPSLKTKIVDGTSLAVAAVLNMIPQGTKDVLLLGNANKISLVLTLSLCKREIQVRMVNKELYECLKQQLQPEMQEHLVLSRSYSSKVWLVGDGVTDEEQMKAQKGSHFVPYSQFPPNKARNDCVYHCTPALLVPESFENLHVCENWLPRRVMSAWRAAGIVHALEKWDGHECGGRVTGVQKAWSAALARGFRPYDDHHHPGITHDGRGGL
What is the function of this protein?
Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes.  Core component of a very-long-chain alkane synthesis complex.
What are the official names of this protein?
Very-long-chain aldehyde decarbonylase GL1-6, Protein GLOSSY 1-6.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KAPR_DICDI
Sequence: MTNNISHNQKATEKVEAQNNNNITRKRRGAISSEPLGDKPATPLPNIPKTVETQQRLEQALSNNIMFSHLEEEERNVVFLAMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEGGSFGELALIYGSPRAATVIARTDVRLWALNGATYRRILMDQTIKKRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVVVTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATVTSIGYTKCVELDRQRFNRLCGPIDQMLRRNMETYNQFLNRPPSSPNLTSQKS
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, Protein kinase A, regulatory subunit, Rapid development protein C.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
Protein: AB17C_XENTR
Sequence: MPEQGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVREMEAPAGTAQPPREEGSGEPAACSLHLSERADWQYSQRELDAVEVFRWRTERGSCLGCMFVRCSPGSRYTVLFSHGNAVDLGQMCSFYIGLGTRINCNIFSYDYSGYGVSSGKPSEKNLYADIEAAWHALRTRYGVTPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLIIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: 143BB_XENLA
Sequence: MDKSELVQKAKLSEQAERYDDMAASMKAVTELGAELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGNDKRQQMAREYREKVETELQDICKDVLDLLDRFLVPNATPPESKVFYLKMKGDYYRYLSEVASGDSKQETVANSQQAYQEAFEISKSEMQPTHPIRLGLALNFSVFYYEILNSPDKACSLAKSAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSETQGEEADNVEGDN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein beta/alpha-B.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_STUS1
Sequence: MKVRASVKKLCRNCKIIRRDGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PNP_DESAL
Sequence: MEVTLERNLGDKPLRIQTGKLAKQASGSVVVSYGETITLVTVVGSQELRPGIDFVPLSVEYQEKVYAAGRIPGNYFRREIGRPSEKETLTARLIDRPIRPLFPKTWRYETQVIATVLSMDQENDPDMLSMVGASAALCISDLPFFTPIACVRVGRIDGELVANPTISQQENCDLNIIVAGSRDGVVMVEGGGQFISEEEMLDAIYFGQESLEPLLEMQEELMEKAGVPKRSADPVEKDEYLAAKVAELADPEIKKALEINDKLERQDAIRDVKKTVMEGLGEEYEDRGKEVSEFIHDRTRVIMRAMVLDEGRRIGGRRFDEVRPITCEVGILPRTHGSALFTRGETQSLGILTLGSSGDEQRVETLYGDETRPFMLHYNFPPYSVREVKRISGPSRRDIGHGGLSTRAIKEVLPSKEDFDYTIRIVSEILESNGSSSMATVCSASLALMDGGVPITNPVSGIAMGLMAEGDKIVVLSDILGDEDHMGDMDFKVAGTKDGITSVQMDIKISSLTREIMEKALAQARVGRLHILEKMLTTISESREEMSPYAPKVFTIQIHPDKIRDIIGPGGKVIRAIQAETGTRVDVDDSGLVKVSAVNLEEGEAALQMIKDITAVPEVGAVYEGTVVKIMDFGAFVAILPGTEGLCHISQLDTKHVKKVSDVVKEGEKIKVKVLELTKDGKIRLSRKALLEEENGKSGPENGAPQRDKNRH
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THYX_EHRRW
Sequence: MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAARISYGRGTKSVSQDAALINYLMRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYSARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQYVTDLLKRDSDMVYETYNKFLIKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKWVPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADNK
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: HTPX_ECODH
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMALCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_DEIGD
Sequence: MSEPTANLQPASRTPLLDRVNSPEDLKRLGRDQLPQLAAELREEIVRVCSVGGLHLASSLGATDLIVALHYVLHSPRDRILFDVGHQAYAHKMLTGRRHLMHTVKKEGGLSGFTKVSESEHDAITVGHASTSLANALGMALARDALGQDYKVAAVIGDGSLTGGMALAALNTIGDLGRRMLIVLNDNEMSISENVGAINRFMRGLQVQKWFQEGEEAGKKAVQAVSKPLANLMSRAKSSTRHFFDPASVNPFAAMGVRYVGPVDGHNVQELVWLIERLVDLDGPTILHVVTKKGKGLSYAEADPIKWHGPGKFDPATGESVPSNAYSWSSAFGDAVTELARLDPRTFVITPAMREGSGLVRYSQVHPHRYLDVGIAEDVAVTTAAGMALQGMRPIVAIYSTFLQRAYDQVLHDVAIENLNVTFAIDRGGIVGADGATHNGVFDLSYLRSIPNVGIGLPKDAAELRGMLKYAQEHAGPFAIRYPRGNVERVPEGTWPELRWGTWERLQDGDDVVILAGGKALEYALKAARDLPGVGVVNARFVKPLDQGMLREVATKARALVTVEDNTVVGGFGSAVLEALSALGLRTPVRVLGIPDAFQDHATVESVHARAGIDAPAIRTVLAELGVDVPLEV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: COAA_MYCMM
Sequence: MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVEEVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANPESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSIKRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_PROMS
Sequence: MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLTDIEKMGNILKNLGVNLVRKNNQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKIRGNKNRLHGTHIKLNCPSVGATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGCTHKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDLQAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIKLNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGSSNFYGLEHLDRGYENFELKLKNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_BLOFL
Sequence: MQYILKLKYYLYNITWKLVFICVMLVLLIVGIHKNIKWVCDYYSGPLSYIIVTGNRFFTTNDDINYIILKSGVLGTFITQDVNIIQKQIKQMPWIQKVSVRKQWPNTLKINLIEYIPIAYWNNEFISTTGVVFSVSECLYNEYSSFVRKMYQEIPILYGPTGKDQEVLNNYLRFSAILKSSNFQIKSVKTDTCYTWQLVLDNNVCLKLGCVNLIERLHYFIKVYPFLVKEMDEKNKYIDYVDLRYNSGCSVRWIHNMIDPVFHAINNVSKGSHDYD
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: G6PI_MYCLE
Sequence: MTSMQAIPDITATPAWDALRRHHDEIGATHLRQFFADNPNRGRELVITVGDLYIDYSKHRITHDTVQLLVDLARAANLEQRRDQMLAGVHVNTSENRSVLHTALRLPRDTELIVDGQNVVQDVHAVLDVMGDFTDRLRSGEWTGATGKRINTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNIDPADLTAKLSDLEPGTTLFIVASKTFSTLETLTNATAARRWLTDALGEAAVSKHFVAVSTNKRLVKDFGINTANMFGFWEWVGGRYSVDSAIGLSLMAVVGRESFADFLSGFHIVDQHFQNAPLESNAPVLLGLIGLWYSDFLGAQSRAVLPYSNDLARFAAYLQQLTMESNGKSTRADGTPVTTNTGEIYWGETGTNGQHAFYQLLHQGTRLVPADFIGFSQPIDDLPTVDGIGSMHDLLMSNFFAQTQVLAFGKTAEEIAAEGTPAEVVPHKVMPGNRPTTSILANRLTPSVLGQLIALYEHQVFTEGVIWGIDSFDQWGVELGKKQAEALLPVITGNASPAQQLDSSTDTLVRRYRTERGRTS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSAB_BACSU
Sequence: MHTKSIELHNEALQHIVGGVNSPSRSYKAVGGGSPVAMEKASGAYFWDVDGNKYIDYLAAYGPIITGHAHPHITEAIKKAAENGVLYGTPTKHEVTFAKMLKEAIPAMDKVRFVNSGTEAVMTTIRVARAYTGRTKIIKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPKSIANEVITVPFNDIDSYKAALEKWGSEIAAVLVEPIVGNFGIVEPKEGFLEQVNELTHNAGALVIYDEVITAFRFMYGGAQDLLQVKPDLTALGKIIGGGLPIGAYGGKQEIMEQVAPLGPAYQAGTMAGNPASILSGIACLEVLKEKGVYEKLDHLGAMLEEGILKHAETHGITITVNRLKGALTVYFSDEKVENYEQAERSDGETFSTFFKLMLERGINLAPSKYEAWFITTAHTEQDIKDTLTAVEDAFKHLKN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYPA1_RABIT
Sequence: MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKALINPANVTFKIYEGMMHSSCQQEMMDVKHFIDKLLPPID
What is the function of this protein?
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (By similarity).  Has depalmitoylating activity toward KCNMA1 (By similarity).  Could also depalmitoylate ADRB2 (By similarity).  Acts as a lysophospholipase hydrolyzing various lysophospholipids including lysophosphatidylcholine (lyso-PC), lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS) (By similarity).  Has much higher thioesterase activity than lysophospholipase activity (By similarity).  Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA (By similarity).
What are the official names of this protein?
Acyl-protein thioesterase 1, APT-1, Calcium-independent phospholipase A2, CaIPLA2, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum. Note=Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum.
Protein: SLT11_CANGA
Sequence: MNKLILGSEEVPQICEKCLGTSNTNENIRMNEVPNGAACKICTLPYTLYHFKKSHRSADIIKTLICKKCAIQRNVCQCCMLDMKLHISIQLRDKLMSIVSGKETITEEAKNIMMKKFIAMKGGSLGSADLTRNVDSIEDILLNLREKLEGKPLNDENEPISALQNKELGDNPHLKSVDIQPYWDKFPLQETFPNAIQIPKGNDSFKSFFIYNIDSSVPEWKISDKITELLGSDSWKTKESIPIIINHKAMCGAFRIGNNELSEKFLQTINNSDNMIRINRSNGLRRGILKVDHFQLFIIPWKQGFSVESFGRTPNESKKIAFALREIIVEEMGGFKDKNDRCKAKEKPKKITKKSKKRVKSIKI
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor SLT11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPPE1_XENLA
Sequence: MMFKHLVPLRNGFNKERTSRLKARLFFLSTIFGSILLVFFFCEFLVYYLVIVKCSWPEVKGAHKEDSTPVLKVMFLADTHLLGEIRGHWLDKLRREWQMERSYQSALWLLQPDIVFILGDVFDEGKWSIPQAWSSDVARFQKMFRHPPHTQLIVLVGNHDIGFHYDMTVYKLSRFEKTFNFTSGKLVSPKGINHILSSSFVLLNSMALEGDDCHICRAAEDQLRRISIKLNCSRMREHPDFQKKCKNVEKTPVSAPILLQHYPLYRISDSECTGEDSASPEEKKVLFKEKYDVLSQDASEKLLQLLQPRLILSGHTHSACEVLHQGKIPEISVPSFSWRNRNNPSFIMGSITATKYSLAKCFLPTENTIIYIYCTASVLLTGYVLACLWLCICQRIHSGRKQKPI
What is the function of this protein?
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.  Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins (By similarity).
What are the official names of this protein?
Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. MPPE1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi- pass membrane protein. Note=Also localizes to endoplasmic reticulum exit site.
Protein: RNH3_PARUW
Sequence: MSSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGKEQAHFIEFYLEPEILESFGFSHPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFSKLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAKYNEIYQDFKNLNHLLAWGHATTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQAFIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVGK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.