PharMolix/UniProtQA huggingface dataset:
Protein: HGD_PSEPW
Sequence: MNRDTSPDLQYLSGFGNEFASEALPGALPVGQNSPQKAPYGLYAELLSGTAFTMARSELRRTWLYRIRPSALHPRFERLARQPLNGPLGGVTPNRLRWNPQPLPTEPTDFIEGWLPMVANSAADKPAGVSVYIYCANRSMERVFFNADGELLIVPEQGRLRIATELGLLEVEPQEIAVVPRGMKFRVELPDGQARGYIAENHGAPLRLPDLGPIGSNGLANPRDFLAPVAHYEEAEGPVQLVQKFLGEHWACELQHSPLDVVAWHGSNVPYKYDLRRFNTLGTVSFDHPDPSIFTVLTSPTSVHGLANMDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLISGAYDAKAEGFLPGGASLHGVMSAHGPDAETCEKAIAADLAPHKIDNTMAFMFETSQVLRPSLQALECPQLQADYDSCWATLPSTFNPNRR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: DPO4_LACLA
Sequence: MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSASAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPEEALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANGIHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKLRYSDFTTLTKRKSLAEKLESPEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATLDMQ
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y563_MYCLB
Sequence: MSGNNHPGDASAEIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITWMVDFGLAAGSRITQLAVVMDVRSRGFTGDLDSVRRELATRNIIPRVVFMEASDDMLVRRYEQNRRSHPLQGEQTLAEGIAAERRMLAPVRATADLIIDTSALSVPGLRESIERAFGGDASATTSVTVESFGFKYGLPMDADIVMDVRFLPNPHWVDELRSLTGQHSAVRDYVLGQPGAAEFLRTYRRLLSLVVDGYRREGKRYMTVAIGCTGGKHRSVAIAEALMGLLQSDLQLSVRVLHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein MLBr00563.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: H2A1E_RAT
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-E.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RIMP_MESM1
Sequence: MFFANIEKHSNFTYYILFFKFCKIRGELVTYKEKLLEKYPDLIYEITWTKEKDDSFLQITLNENNLEKITEYSKEISNILDNYEKELPSKYFLDISSRGINLSIQKENLDNYLEKYIEISLVNETKKIKGILWEIKNETIILKVNFKGQFRKIEYKKNNINLIEEVIK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
Protein: CTAA_BRUA2
Sequence: MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTWPLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WLS_HUMAN
Sequence: MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDARKNHHKTKWFVPWGPNHCDKIRDIEEAIPREIEANDIVFSVHIPLPHMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDAFAEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYECDVLPFMEIGSVAHKFYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDIGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE
What is the function of this protein?
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism.  This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins (PubMed:34587386).  Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).
What are the official names of this protein?
Protein wntless homolog, Integral membrane protein GPR177, Protein evenness interrupted homolog, EVI, Putative NF-kappa-B-activating protein 373.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Note=Co-localizes with the adaptin AP2A2 at distinct punctae.
Protein: FPA_ARATH
Sequence: MALSMKPFRADDSGFQSNNLWVGSLTPETTESDLTELFGRYGDIDRITVYSSRGFAFIYYRHVEEAVAAKEALQGANLNGSQIKIEYARPAKPCKSLWVGGIGPNVSKDDLEEEFSKFGKIEDFRFLRERKTAFIDYYEMDDALQAKSMNGKPMGGSFLRVDFLRSQAPKKEQWAGSYDNRNGNMNHKPQYPHSYEDFKGDVQPSKVLWIGFPPTATQCNDEQILHNAMILFGEIERVKSYPSRNFALVEFRSAEEARQCKEGLQGRLFNNPRIKIMYSNDELPPEQDDTSFYSGMKRSRTDMFNNDPSFVSSPHSTGIPGSMRPLRGTNERSYNGAEYNDVVGKEPNWRRPSANGTGILPSPTGPGILPSPAQGTRRPMRSNPDSWEGYDPAQLVRESKRTRRDGSVDGFTPMGVDERSFGRGSVAARPIRGPPDSDHIWRGMIAKGGTPVCCARCVPMGKGIETKLPEVVNCSARTDLNMLAKHYAVAIGCEIVFFVPDREEDFASYTEFLRYLSSKDRAGVAKLDDGTTLFLVPPSDFLTDVLQVTRQERLYGVVLKLPPPAVPVTASYRQESQSNPLHYMDQARDSPANASHSLYPPRENYIRGAPEHLTAASKPSVSEPLRIPNNAAPQAGVSLTPELLATLASILPATSQPAAPESHQPMSGPSTVVSTAHQSNGLYNGEAPSQAWKRGPQTVHDASNQSFQQYGNQYTPAGQLPPPPSRYPPASNNPNYTSGMVHGNMQYQSQSVNMPQLSPLPNMPHNNYSMYTQGSSNHPVSQPMVQQYQPEASMPNQNYGPIPSYQQANFHGVTTNQAQNLNPSQFQAAMQPPADKANLEPQNQALRLQPMISGDGQGTTDGEVDKNQRYQSTLQFAANLLLQIQQKQQQQSSGTPAGQGP
What is the function of this protein?
Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels.  Required for RNA-mediated chromatin silencing of a range of loci in the genome.  Cotranscriptionally recognizes aberrant RNA and marks it for silencing.  Controls alternative cleavage and polyadenylation on pre-mRNAs and antisense RNAs.  Acts redundantly with FCA to prevent the expression of distally polyadenylated antisense RNAs at the FLC locus.
What are the official names of this protein?
Flowering time control protein FPA.
What is the protein family that this protein belongs to?
Belongs to the RRM Spen family.
Protein: SSRP_MARMS
Sequence: MSKVKKKSTSTGTIALNKRAKYDYFVDQKFEAGLVLSGWEVKSLREGKAQLVDAFVIIHQNEAWLVGARITPLLSASTHVVCEPMRQRKLLLNRKELERIIQVTEQKGKTCAAMALYWKGNKIKCEVALVTGKKEHDKRDTERDRDWSRDKERLMKHNA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YCF63_NEOYE
Sequence: MLQIELQKWIQRFSSTIRLFFRLLIRLKTIKVNTNNLVEQIYIVGPGSLNITLLTACFISMVFTMQIAKEFLYLDAASAIGAVIVIAFTRELSPVLTAVIIAGKIGSSFTAEIATMETTEQIDALYLLNTNPIDYLVFPKVASCFLMLPILSIISLTASIAISLFVAFVMYDIPSSVFLKSAFNALSISDFLICLEKSMFFAIIIGFISCQWGLTSNGGAKGVGNSTTSSVVTILFTVFITDFVLSYFMFQTTGSSIAQANNI
What is the function of this protein?
Could be part of an ABC transporter complex.
What are the official names of this protein?
Probable ABC transporter permease protein ycf63.
What is the protein family that this protein belongs to?
Belongs to the MlaE permease family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: FEN1_BLAGS
Sequence: MGIKHLYQVIQENAPDAVKAGEIKNHFGRKVAIDASMSIYSFLVAVRSDGQQLMSETGETTSHLMGMFYRTLRIVENGIKPVYVFDGAPPKLKSGELAKRFMRKSEAAEAHEEAKEVGTAEDVEKFSRRTVRVTREHNEECKKLLKLMGVPYINAPTEAEAQCAVLARAGKVYAAASEDMDTLCFDSPILLRHLTFSEQRKEPILEIHLDRVLEGLDMDRKQFVDLCILLGCDYLDPIPKVGPNTALKLIRDHGSLEKVVEAIQSDPKKKYTIPEDWPYKDARELFFDPDVRKADHPDCNFKWEAPDVEGLVKFLVEEKAFSEDRVRNGAARLQKNLKTAQQSRLEGFFKPIAKTEQEKATLKRKHEEKLELQKKKKKEEAKAKKEAKSKPRGAV
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: HBB_PERCA
Sequence: VHLTDAEKALVTGLWGKVKPDELGGEALGRLLVGYPWTQRFFDSFGDLSSASALMGNPKVKAHGKKVLDSFSEGLKHLDNLKGTFASLSELHCDKLHVDPENFKLLGNMLVLVLAHLLGKDFTPAAQAAYQKVVAGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PDH_PROCL
Sequence: NSELINSILGLPKVMNEA
What is the function of this protein?
Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas.  May also function as a neurotransmitter and/or neuromodulator.
What are the official names of this protein?
Pigment-dispersing hormone, PDH.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: LCN12_HUMAN
Sequence: MRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQGNQFQGEWFVLGLAGNSFRPEHRALLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVLIPAAQPGQFTVDHGVEPGADREETRVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLLPPGTLDQFICLGRAQGLSDDNIVFPDVTGWSPQASVC
What is the function of this protein?
Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis.  May play a role in male fertility (By similarity).
What are the official names of this protein?
Epididymal-specific lipocalin-12.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY_AERS4
Sequence: MRVYLDLMQKILDEGTVKSDRTGTGTVSLFGHQMRFNLAQGFPLVTTKKCHLRSIIHELLWFLNGDTNTAYLKEQGVSIWDEWADENGDLGPVYGAQWRSWPAADGAVIDQIQRAVDDIKHNPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTHMMAQQCDLEVGDFVWTGGDVHLYSNHMEQTALQLSREPRPLPQLAIKRKPDSIFDYRFEDFEILGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICR_SHIBS
Sequence: MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: IGS10_RAT
Sequence: MQVRGREVSGLLISLTAVCLVVTPGSRACPRRCACYVPTEVHCTFRYLTSIPDGIPANVERINLGYNSLTRLTENDFDGLSKLELLMLHSNGIHRVSDKTFSGLQSLQVLKMSYNKVQIIRKDTFYGLGSLVRLHLDHNNIEFINPEAFYGLTSLRLVHLEGNRLTKLHPDTFVSLSYLQIFKTSFIKYLFLSDNFLTSLPKEMVSYMPNLESLYLHGNPWTCDCHLKWLSEWMQGNPDIIKCKKDRSSSSPQQCPLCMNPRISKGRPFAMVPSGAFLCTKPTIDPSLKSKSLVTQEDNGSASTSPQDFIEPFGSLSLNMTDLSGNKADMVCSIQKPSRTSPTAFTEENDYIMLNASFSTNLVCSVDYNHIQPVWQLLALYSDSPLILERKPQLTETPSLSSRYKQVALRPEDIFTSIEADVRADPFWFQQEKIVLQLNRTATTLSTLQIQFSTDAQIALPRAEMRAERLKWTMILMMNNPKLERTVLVGGTIALSCPGKGDPSPHLEWLLADGSKVRAPYVSEDGRILIDKNGKLELQMADSFDAGLYHCISTNDADADVLTYRITVVEPYGESTHDSGVQHTVVTGETLDLPCLSTGVPDASISWILPGNTVFSQPSRDRQILNNGTLRILQVTPKDQGHYQCVAANPSGADFSSFKVSVQKKGQRMVEHDREAGGSGLGEPNSSVSLKQPASLKLSASALTGSEAGKQVSGVHRKNKHRDLIHRRRGDSTLRRFREHRRQLPLSARRIDPQRWAALLEKAKKNSVPKKQENTTVKPVPLAVPLVELTDEEKDASGMIPPDEEFMVLKTKASGVPGRSPTADSGPVNHGFMTSIASGTEVSTVNPQTLQSEHLPDFKLFSVTNGTAVTKSMNPSIASKIEDTTNQNPIIIFPSVAEIRDSAQAGRASSQSAHPVTGGNMATYGHTNTYSSFTSKASTVLQPINPTESYGPQIPITGVSRPSSSDISSHTTADPSFSSHPSGSHTTASSLFHIPRNNNTGNFPLSRHLGRERTIWSRGRVKNPHRTPVLRRHRHRTVRPAIKGPANKNVSQVPATEYPGMCHTCPSAEGLTVATAALSVPSSSHSALPKTNNVGVIAEESTTVVKKPLLLFKDKQNVDIEIITTTTKYSGGESNHVIPTEASMTSAPTSVSLGKSPVDNSGHLSMPGTIQTGKDSVETTPLPSPLSTPSIPTSTKFSKRKTPLHQIFVNNQKKEGMLKNPYQFGLQKNPAAKLPKIAPLLPTGQSSPSDSTTLLTSPPPALSTTMAATQNKGTEVVSGARSLSAGKKQPFTNSSPVLPSTISKRSNTLNFLSTETPTVTSPTATASVIMSETQRTRSKEAKDQIKGPRKNRNNANTTPRQVSGYSAYSALTTADTPLAFSHSPRQDDGGNVSAVAYHSTTSLLAITELFEKYTQTLGNTTALETTLLSKSQESTTVKRASDTPPPLLSSGAPPVPTPSPPPFTKGVVTDSKVTSAFQMTSNRVVTIYESSRHNTDLQQPSAEASPNPEIITGTTDSPSNLFPSTSVPALRVDKPQNSKWKPSPWPEHKYQLKSYSETIEKGKRPAVSMSPHLSLPEASTHASHWNTQKHAEKSVFDKKPGQNPTSKHLPYVSLPKTLLKKPRIIGGKAASFTVPANSDVFLPCEAVGDPLPIIHWTRVSSGLEISQGTQKSRFHVLPNGTLSIQRVSIQDRGQYLCSAFNPLGVDHFHVSLSVVFYPARILDRHVKEITVHFGSTVELKCRVEGMPRPTVSWILANQTVVSETAKGSRKVWVTPDGTLIIYNLSLYDRGFYKCVASNPSGQDSLLVKIQVITAPPVIIEQKRQAIVGVLGGSLKLPCTAKGTPQPSVHWVLYDGTELKPLQLTHSRFFLYPNGTLYIRSIAPSVRGTYECIATSSSGSERRVVILTVEEGETIPRIETASQKWTEVNLGEKLLLNCSATGDPKPRIIWRLPSKAVIDQWHRMGSRIHVYPNGSLVVGSVTEKDAGDYLCVARNKMGDDLVLMHVRLRLTPAKIEQKQYFKKQVLHGKDFQVDCKASGSPVPEVSWSLPDGTVLNNVAQADDSGYRTKRYTLFHNGTLYFNNVGMAEEGDYICSAQNTLGKDEMKVHLTVLTAIPRIRQSYKTTMRLRAGETAVLDCEVTGEPKPNVFWLLPSNNVISFSNDRFTFHANRTLSIHKVKPLDSGDYVCVAQNPSGDDTKTYKLDIVSKPPLINGLYANKTVIKATAIRHSKKYFDCRADGIPSSQVTWIMPGNIFLPAPYFGSRVTVHPNGTLEMRNIRLSDSADFTCVVRSEGGESVLVVQLEVLEMLRRPTFRNPFNEKVIAQAGKPVALNCSVDGNPPPEITWILPDGTQFANRPHNSPYLMAGNGSLILYKATRNKSGKYRCAARNKVGYIEKLILLEIGQKPVILTYEPGMVKSVSGEPLSLHCVSDGIPKPNVKWTTPGGHVIDRPQVDGKYILHENGTLVIKATTAHDQGNYICRAQNSVGQAVISVSVMVVAYPPRIINYLPRNMLRRTGEAMQLHCVALGIPKPKVTWETPRHSLLSKATARKPHRSEMLHPQGTLVIQNLQTSDSGVYKCRAQNLLGTDYATTYIQVL
What is the function of this protein?
Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (By similarity).  May be involved in the maintenance of osteochondroprogenitor cells pool (PubMed:14962803).
What are the official names of this protein?
Immunoglobulin superfamily member 10, IgSF10, Calvaria mechanical force protein 608, CMF608.
What are the subcellular locations of this protein?
Secreted.
Protein: ITIH5_HUMAN
Sequence: MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMTLGQGMSREL
What is the function of this protein?
May act as a tumor suppressor.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H5, ITI heavy chain H5, ITI-HC5, Inter-alpha-inhibitor heavy chain 5.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOB_ALIF1
Sequence: MFNFANFYQLIAQDTVLQPWLNTLPQQLTDWQNAEHGDIERWIKALKKIPEGCADNIDLKSSVTLSNNTPLIDGERKKLENLLQTFHPWRKGPFTVHDIHIDTEWRSDWKWDRLLPHITPLKNRSVLDVGCGNGYHMWRMLGEDARLCVGIDPSHLFLIQFEAIRKLMGNDQRAHLLPLGIEQLPELNAFDTVFSMGVLYHRRSPLDHLIQLKNQLVAGGELVLETLVIDGDENAVLMPVDRYAQMRNVYFFPSARALKVWLESVGFVDVKIVDECVTTTGEQRSTEWMKHNSLPEYLDPNDSTKTIEGHPAPKRAILIAKKPD
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: AT133_MOUSE
Sequence: MDKEERKTINKGQEDEMEIHGYNLCRWKLAMVFVGVICTGGFLLLLLYWLPEWRVKATCVRAAVKDCEVVLLRTTDEFRVWFCAKIHFLPVENQPNLNAKCLVNEVSNGHAVHLTEENRCEMNKYSQSQSQQMRYFTHHSIRYFWNDAIHNFDFLKGLDEGVSCASLYEKHSAGLTQGMHAYRKLIYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSVDEYYYYALAIVIMSVVSIISSLYSIRKQYVMLHDMVATHSTVRVSVCRENEEIEEIFSTDLVPGDVMIIPLNGTVMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGMGEEQYSPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVVVAGIGFIYTIINSILNEKEVQEIIIKSLDIITITVPPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENTRFLLPEDNVCSEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPSKQLLPEPTTAGNQEMELFELPAIYEIGIVRQFPFSSALQRMSVVARTLGEKRMDAYMKGAPEVVASLCKPETVPVDFEKVLEDYTKQGFRVIALAHRKLESKLTWHKVQHISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDNMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYTDSLSQCSESSAIDSEAIPIKLAHDSLEDLEVTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLVEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALMTSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIVISVGFQSLGFFWVKQYKVCDPNSDVCNTTRSACWNSSHLYNGTELDSCKIQNYENTTVFFISSFQYLTVAVAFSKGKPFRQPCYKNYFFVISVIILYVFILFIMLHPVASVDQVLEIMCVPYQWRIYMLIIVLINAFVSITVEESVDRWGKCCLSWALSCRKKTPKAKYMYLAQELRFDPEWPPKPQTTTEAKAVVKENGSCQIITIA
What is the function of this protein?
ATP-driven pump involved in endocytosis-dependent polyamine transport.  Uses ATP as an energy source to transfer polyamine precursor putrescine from the endosomal compartment to the cytosol.
What are the official names of this protein?
Polyamine-transporting ATPase 13A3, Putrescine transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Recycling endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Mainly targeted to the recycling endosomes and to a lesser extent to the early and late endosomes.
Protein: ARLY_RHORT
Sequence: MSSSTPTTPSIERTASTIWGGRFDSGPSAVMEAINASIGFDKRLYRQDIAGSKAHCTMLVATGILSKADGEAILGGLDRILAEIEAGDFPFSVALEDIHMNIESRLKDLIGEAAGRLHTARSRNDQVATDFRLWVRDAIDGVEGALARLQDVLITRAEEHADTVMPGFTHLQAAQPVTFGHHLLAYVEMIGRDRGRFHDARVRLNESPLGSAALAGTSFPIDRAMTAQILGFDRPCANSLDGVSDRDFALEFLAAASIASIHLSRLAEELVIWTSAQFGFVRLPDAYSTGSSIMPQKRNPDAAELVRAKAGRVIGDLASLLIVMKGLPLAYSKDMQDDKEPVFEAADTLELCIAAMTGMMETITPKVDRLRTAAGQGFTTATDLADWLVRALGTPFRHAHEVSGALVKMAEKKGVGLEDLSLAEMRTIEPRLTDEAIKVLSVDWSVRSRTSFGGTAPDNVRAACAAARARYAAKAPPR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK19_THAWE
Sequence: MLNLDNQKAIDNLHKNFIKPNLPKIQIGDTVKLGVKIIEGNKERVQFYEGTVIAKKNSSINTTITVRKVLQGIGIERIFLIHSPKIASIEVLRHSKVRRSKLYYLRNLRGKASRLKQRFE
What are the official names of this protein?
50S ribosomal protein L19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BLACE_HUMAN
Sequence: MMKDIIPASSWASEESTDLQNGSFPLSVAPRSEFPRRRALEDWLLSVFLADQAESEGQLVLERVRDTPPPVTSPRGDGICVSRGKAPSSPGGSTHAWLYLTRHFPWSPFPHGGWTDTSEPCVLETLGGSSLAALRGNSLWVQSSGACAFCVYESLIEQSLPNERFEELLLGPSPGEVMK
What are the official names of this protein?
B-cell acute lymphoblastic leukemia-expressed protein.