PharMolix/UniProtQA huggingface dataset:
Protein: EIF3C_ASPTN
Sequence: MSRFFARGGSDSESSSEDEQELYSDREEEEQFSDSEEESSEAESSEEESSDDEGAGASRFLKNVSESEESEDEERVTVVKSAKDKRLDELEGIIKAIENAEKINDWAVISSEFDKLNRQIVKVTQAGPTPKIYIQTVADLEDFVNETIAKQKSSNKKMNASNAKGFNAVKQRIKKNNKEYATLIEKYRADKDGFMAGGDEEPKPVISAPRISKVERVEAPVAVTATADDDGFATVGRGGKTLQYTPESILKHLRVIVESRGKKNTDRFEQIRTMEKLLEVAQNPYQRIRIYLTLISTRFDLTSSSSANYMSVDQWKLAQQEFSTLLSVLESNREYVVTEGAEEWEDDEKQPQVAAGETLHVPGSIVSYVERLDDELTRSLQQIDPHTAEYIERLSDEKELYTNLVRTQVYAEALTTSEKSDPRQDSLNRVIMRRLEHIYFKPAQVVTILEEGTWKSLPSNLASDITPRANSGEVTSLVQTLCNYLFRHSDGILRARAMLCQIYFLALHDQYYRSRDLMLMSHLTENIANFDVSTQILFNRTLVQIGLCAFRAGLVYEAQNTLSEVCGSGRQKELLAQGIILQRYSTVSPEQERLERQRQLPFHMHINLELLECIYLTSSMFLEVPLMAQTSSSPEMKRRVISKTFRRMLDYNERQVFTGPAENTRDGVIMSAKFLAAGDWKKAAEMLNSIKIWDLMPQPEKIKEMLSQQIQEEGLRTYLFTYAPFYDSVSIATLSNMFELPEKKIQAIISRMISHEELAAALDQVNNAIVFRKGVELSRLQSQIVTLADKSMNLLEANEKTLEQRTQGMANAFQRDQGAGARGGRGAGRGGQARGGPRFPGGQQGRRPGGQQFSGGALGGAIKA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_SALCH
Sequence: MSVSKKPMVLVILDGYGYREEQQDNAILNAKTPVMDALWAKRPHTLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKERTFFANPVLTNAVDQAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPRSAEASLKKFEDKFAAQGKGRVASIVGRYYAMDRDNRWDRVEKAYDLMTLAQGEFQADTAVAGLQAAYARDENDEFVKATVIRAEGQADAAMEDGDTLIFMNFRADRAREITRAFVNADFDGFARKKVVNLNFVMLTEYAADIKTTVAYPPASLANTFGEWMAKNDKTQLRISETEKYAHVTFFFNGGVEEPFAGEERILINSPKVATYDLQPEMSSAELTEKLVAAIESGKYDTIICNYPNGDMVGHTGVMEAAIKAVEALDNCIDQVTKAVESVGGQLLITADHGNAEQMRDPATGQAHTAHTNLPVPLIYVGEKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGKPLFIVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: VP8_FDVS
Sequence: MTTGTDVRISLRLLFYELWDNNAKLTKNKTTTPTTSKTTSKILFNSKRTTPTHGYDADYIAELSNNFEFAGFTAPTPHNIRKAFTRLKIMFERMNRYPDEIFLSRHRMLGFVIYQPETSGPIPAFHPKCKFYKLSDNHTHDEKIEIVKNHILNGEIVKTVDLKIDQSFESYYYDKSNAQASQKFLASMHTCDFSFLSFPYINDLTATELGLLPEWAAILLSYMKIINVRGIYNDVVECIDPSQQFCVFEIIGSLTGISNGHFWSVLNDRRSMDVIAKEVEKIALDNQPFXKDGNLNHLLFNSINLSDPLNFNIFHYSFKLKIFPTTLNPLDDLVLLRMKDLIKAFNAGNDVQVIGNKCIGKTRLTAELKKKYLNLLIIDSDDYGKFITLLLNNCPNLFLNNDFEINDEVFEEEIFNVTVIEYANVIRDGTIVIETFFERLMFEIMSLNLTNGEYDVDAIFHSFNARFHAIVNSSMIGYRLFFTKFRKLMFDNFNYTQVLHFVHSYSELSFYPHCVAYITLEPSYNPCCLLYKNRVKRFLSITRSDKGVSSELFLHQFYEKFTTKVNPTPVFVFRYYFGLTNGLSISELALDENT
What is the function of this protein?
Minor inner capsid component.  Displays NTPase and RNA 5'-triphosphatase (RTPase) activities.  May function as a cofactor of polymerase VP1.  Associates with microtubules and plays a role in the formation, structural organization and morphology of viral inclusions, where the assembly of cores and the replication of viral RNA occur (By similarity).
What are the official names of this protein?
Microtubule-associated protein VP8.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host cytoskeleton.
Protein: MURA_THEP1
Sequence: MGKLVVQGGTVLEGEVEISGSKNAALPIMAAAILCDEEIILKNVPRLQDVFVMIDILRSIGFRVEFDENELKIKRENDISQEVPYELVRKMRASFNVLGPIAVRTGRAKVALPGGCSIGVRPVDFHLEGLKKMGFSIKVEHGFVEATFERRTDQVTITLPFPSVGATEHLMTTAALLEGTRVVIENAAMEPEIVDLQNFINRMGGRIEGAGTSRIVIEGVEKMQGVEYSIIPDRIEAGTYLVAIAASRGKGLVKNVNPDHLTNFFEKLEETGVKLKVFGNEVEIEMRERPEAVDVTTNPYPGFPTDLQPQMMAYLSIASGVSVITENVFKTRFLHVDELKRMGADIEVSGNVAIVKGVEKLSGAPVEGTDLRATAALLIAGIIADGVTEISNVEHIFRGYEDVIDKFSKLGAKIEYVEKEN
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_VIBC1
Sequence: MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGSIKDDIKGAVSSSVASTERLKELGIEVYECNDVAMLDIYVDGADEINAAREMIKGGGAALTREKIVAAISEKFVCIVDGTKAVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGVTTDNGNVILDVHNMQITNPKELEDKINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: CYB_TACSP
Sequence: MTNLRKSHPLMKIVNHTFIDLPTPSSISAWWNFGSLLGICLLLQILTGLFLAMHYSSDTSTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFLHIGRGTYYGSYTLSETWNIGILLVFSTMATAFLGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLSRFFAFHFIMPFIITALVMVHLLFLHETGSNNPTGLNSNADKIPFHPYYTIKDILGFVLLCFILLSLTLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALILSILILIILPLLHTSPLRSLTFRPFSQCLFWILVADLITLTWIGGQPVEHPFIIIGQAASILYFSIFLILMPLAGILENKIMKM
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YABA_STRA1
Sequence: MDKKDLFDAFDDFSQNLLVGLSEIETMKKQIQKLLEENTVLRIENGKLRERLSVIEAETETAVKNSKQGRELLEGIYNDGFHICNTFYGQRRENDEECAFCIELLYRD
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: RIHA_SALHS
Sequence: MALPIIIDCDPGHDDAIALVLALASPELEVKAITSSAGNQTPEKTLRNVLRMLTLLKRPDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSGTAVELMAKTLRESAQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMALGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRAIGNPISTIVAELLDFFMEYHKDEKWGFVGAPLHDPCTIAWLLKPEIFTTVERWVGVETQGKYTQGMTVVDYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: GSA_DEIDV
Sequence: MTSSTTTRSEALFERARAVTPGGVNSPVRAFKSVGGVPRFIREAHGAYLTDMDDTRYVDYIGSWGPMILGHDHPTIREAIATALTGGTSFGAPGEREVELAELVTRLTGAGRVRFVNSGTEATMSALRLARGFTGRKFIVKFRGNYHGHADGLLVEAGSGLLTNAEGVLGSAAPSSAGVPEEYASLTLVSEYNDPAALDALMRLRGHEVAAVIFEPVVGNAGVLVPTPDFLEALHRVKASGALLVADEVMTGFRLSLNGATGLLGLEPDLTCWGKIIGGGLPVGAYGGRADVMDFVSPQGPVYQAGTLSGNPLAMAAGLATLQTLEADPGIYGRLEAYTAALASGLRAAADEAGVPVSINRVGSMLTAFHQDVPDGSIRTYADAARSDTTGFATWFQGMLARGVYWAPSQFESIFVSGAHTDRELNVTLEAARSAYGGTPV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_ACTP7
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIASVLAEEGYVESFKIVEGSKPELEITLKYFQNKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SIX5_LEIHE
Sequence: DGYIRGGDGCKVSCVIDHVFCDNECKAAGGSYGYCWGWGLACWCEGLPADREWKYETNTCG
What is the function of this protein?
Excitatory insect beta-toxins induce a spastic paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  This toxin is active only on insects.  It operates by inducing a fast contraction paralysis without depressant activity.  It is more similar to the excitatory toxins in its mode of action and the depressant toxins in its primary structure.
What are the official names of this protein?
Insect toxin LqhIT5, Lqh IT5, Toxin 5.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BOA15_BOTFB
Sequence: MQAFYLDSEVWSSFDFTRQPSSVILSAEVLAYLDDVDETKRKYFSSTHTWMPIISKMRLNRLTDSAVGKTRVDIALLLLCMKLVPDGVAEDENKPSDLYLTAKQLCATLERNCLLTLRSLQANLLLAVYEVGHAIYPAAALTVGCCVRQGVALGLHNKDAPQLGGNVRSWVDWEERQRG
What is the function of this protein?
Transcription factor that probably coregulates the gene clusters that mediates the biosynthesis of botcinin acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (Probable).  Botcinin acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (Probable).
What are the official names of this protein?
Transcription factor BOA15, Botcinic acid biosynthesis cluster B protein 15.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECF_PSEAE
Sequence: MSLTRVSVTAVRNLHPVTLSPSPRINILYGDNGSGKTSVLEAIHLLGLARSFRSARLQPVIQYEEAACTVFGQVMLANGIASNLGISRERQGEFTIRIDGQNARSAAQLAETLPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFLPVWQRLQKALRQRNSWLRHGKLDPASQAAWDRELSLASDEIDAYRRSYIQALKPVFEETLAELVSLDDLTLSYYRGWDKDRDLLEVLASSLLRDQQMGHTQAGPQRADLRIRLAGHNAAEILSRGQQKLVVCALRIAQGHLINRAKRGQCVYLVDDLPSELDEQHRMALCRLLEDLGCQVFITCVDPQLLKDGWRTDTPVSMFHVEHGKVSQTTTIGSEA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_MYCSJ
Sequence: MCRRAPRSIPLRCAHAPRRDVYQEIPISSFADQTFTAPAQIRNFCIIAHIDHGKSTLADRMLGITGVVADRDMRAQYLDRMDIERERGITIKAQNVRLPWEVNGEKFVLHLIDTPGHVDFTYEVSRALEACEGAILLVDAAQGIEAQTLANLYLALDRDLAIIPVLNKIDLPAADPDRYAGELAHIIGCEPSDVLRVSGKTGAGVRELLDEVVRLVPPPTGDADAPARAMIFDSVYDIYRGVVTYVRVVDGKITPRERIAMMSTGATHELLEVGIVSPDPKPSAGLGVGEVGYLITGVKDVRQSKVGDTVTTARHGAKEALTGYREPRPMVYSGLYPVDGSDYPVLREALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRERLEREFNLDLISTAPNVVYRVEKDDGTEIVVTNPSDWPEGKVRTVYEPVVKTTVIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDSLKSRTRGYASLDYEEAGEQEADLVKVDILLQGEAVDAFSAIVHKDGASAYGNKMTTKLKELIPRQQFEVPVQAAVGSRIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVDVPQEAFVAALSTDAAGDKPKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL23_ECOUT
Sequence: MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TLP_CLOBJ
Sequence: MKNKPDDRRDNVDKIQYNITKTIQNCELADEMIAKTDDEKTKKTLIEKNQRRREALDGMREEIKDEARDKKNGYM
What are the official names of this protein?
Protein Tlp homolog.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
Protein: MMPL2_MYCTO
Sequence: MSERHAALTSLPPILPRLIRRFAVVIVLLWLGFTAFVNLAVPQLEVVGKAHSVSMSPSDAASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQDFWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGPAALNADQAEAGDKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFIALLADHNIFSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFKLFDPKRRMNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYDLRKFMPASMPSNVGDAAAGRHFSRARLNPEVLLIETDHDMRNPVDMLVLDKVAKNIYHSPGIEQVKAITRPLGTTIKHTSIPFIISMQGVNSSEQMEFMKDRIDDILVQVAAMNTSIETMHRMYALMGEVIDNTVDMDHLTHDMSDITATLRDHLADFEDFFRPIRSYFYWEKHCFDVPLCWSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHGTLGAFYKQQARNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAARFVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLLIAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLAMSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVFSDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAPRRLVRALLLPSGQHPSATGAHE
What are the official names of this protein?
Probable transport protein MmpL2.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOM_SCHPO
Sequence: MLRRKIQTYLSRSHIRRGLCGLRFFQTQRLHTDYMPIEAYEPYKNELKSKIGKDFIIDLSYKSGTASLFEACVYNGDFLRSKQLLKSFIDHNKGDKILLPMINLYIREIIQRGSFELTDVLSNAKELLQQARLNGDSLTYALLCQASLNPTQRQLGLPVLHELIHNWRSANGKVIDILMHESVFSPEEVKLIMDQLNIPINNFTPSQLQLLGITNSTIVGESENGKDQNGDSSLKEKQPDVETTVTKSANLNALRSSLSSLLTESIDLPIDEVSLEFGNQGDTFNLARQKLLEKSAILSAAEVWKSEHESVLNRGNLQVPKNVSSLFYSWYVQLEQLFKEEISLIDDLALNESLDKKNDRLIYGPFLKLLSSKKLAALTIMEVAQLSTNPRYDRGARVTTLLGGLGRSFEREFLSEQIQRQEKNKSYKDKKRLKELFNDPRKFRQAVKNLRLSNTRDNIVLNPSVDSWPSAIVMKVGSVALCLLLSVAKIEVTAKDLSTGGILKQEVAAFVHTYQYSNGRKVGMIVPHVEFYKLLSRDIEKPHLHPQLLPMLVTPKPWTSWIDGGYYYSRQPLVRLKGALEQVDYLMKASENGQLDELFKAVSSLGKVSWRINQRLFNVLIRIWNSGEKFLSIPPREVKCDMPPYPKNSINPRDKVIWHTRRKELAALKTGAHSQRCDFNYKLEIARAFLNEKFYFPHSLDFRGRAYPLSSHLHHVSNDVCRGLLEFSTGKPLGPKGLNWLKVHLANLFGISKKDFATRQAFVDDNMQEVFDSADRPLDGNKWWSKADDPFQALAACFEIAEAVRSGDHESYISHIPIQQDGTCNGLQHYAALGGDIEGAKQVNLWPSDHPSDVYEAVAEIVRGFLKKDAEAGDEMANFLKDKVTRSVVKPTVMTNVYGVTYVGARKQISEKLENIDGMEKLKVADYANYLTKKVFEALRSLFTQAHEIQDWLSACCNLITHSLPADYIKEGIKDELTPVVWTTLLNLPIVQPYRNYKSRQIRTNLQTVFIEERDRTATVQPHKQATAFPPNFIHSLDATHMFMTCLKCSEQNINFAAVHDSYWTHACDVDQMNSLLREAFVLLHSNNIMERLKQEFEERYKGFLVSKKAIKANDEDLKAKFGNKSYIPLEFPPLPARGALDLKKVLESKYFFS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Combines in the mitochondrion with mitochondrial transcription factor mtf1 as a holoenzyme to recognize and initiate transcription at the core mitochondrial promoters.
What are the official names of this protein?
DNA-directed RNA polymerase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PLCD1_HUMAN
Sequence: MDSGRDFLTLHGLQDDEDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDHSQTDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNGTFNPRALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQHPSATLFVKISLQD
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed:9188725).  Essential for trophoblast and placental development (By similarity).  Binds phosphatidylinositol 4,5-bisphosphate (PubMed:7890667, PubMed:9188725).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1.
Protein: LIS1_YEAST
Sequence: MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLINVESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNYTNSSKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSIDVLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTLKGHLSWVRDISIRGQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNCLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.  Following plus end binding, dynein may be offloaded to the cortex by NUM1.  Required for viability in the absence of the kinesin-related microtubule-dependent motor protein CIN8.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Note=Localizes to the plus ends of cytoplasmic microtubules.
Protein: PTSO_PROMH
Sequence: MTQYRRVAIKNRLGMHARPAMKLFDLVNTFQSTVTLRNHEGVEAQADSVIAMLMLDSEQGSHIDIEASGCDEKEAIDAIIALFESGFDED
What is the function of this protein?
Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr.  Phospho-NPr then transfers it to EIIA-Ntr.  Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins.
What are the official names of this protein?
Phosphocarrier protein NPr, Nitrogen-related HPr.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_NEIM0
Sequence: MPIPKAFALLGPTACGKTALALKIAETLPVEIISLDSALVYTGMDIGTAKPSASERAFVPHHLIDIITPVQTYSAARFVEDCTRLIGEITARGKCPLIVGGTMMYFRALTQGLNDLPEADACLRADLDEQKQMYGLDFLYRTLQKVDPETACRLKPNDSQRIERALEVYYLTGKPMSEHLGRQSPHTLPFDLHTAALIPENRARLHENIALRFHLMLEQGFIGEVENLRRRYPGLTADSPAIRCVGYRQAWEYLDGKTDFPAFVEKGIAATRQLAKRQLTWLRKTPLDCVADPFSDGTSCTRLIEAAKRFFGA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AROD_ECOL5
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTYRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: FPG_MYCPA
Sequence: MPELPEVEVVRRGLHAHVVGKTIGAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRGKYLWLLLDGCDTALVVHLGMSGQMLLGAVPRAEHVRISALLDDGTVLSFADQRTFGGWMLADLLEVDGSILPRPVAHLARDPLDPRFDAAAVVKVLRRKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARIAATMTGRQLTAVLDAAAEVMRDALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGESCRRCGAVMRREKFMNRSSFYCPKCQPRPRL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS16_AZOSB
Sequence: MVVIRLARGGAKKRPFFNIVAADSRNRRDGRFIERVGYYNPVASGAEKGLVVNTERLAYWEQNGAQLSPTVARLVKQAAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.