PharMolix/UniProtQA huggingface dataset:
Protein: RAD5_EMENI
Sequence: MNFDASNDRPLKKRRFFVDDPLDTAVTPAEKSPALDASSSASTHTDPNYSANGSPAQIQTQQEYNFSNGGHATQPATAAGTRTHQAQSPAHDTLSDFDTEAFVSIVGEQVSPETLSQIRKLSDGSLEKAINVYFDGSWKNAGSPGSSQTTLLSCERNASRPSPLHTSREQGTGPAENGADSVTEPISRSKLQPARRYLGAFGVEAWATRSGIGLIKHGDTVNIERARSQPLSTRGRTGKLRVNQKGDVLTRFTNTAGQEIGRLPRETAEWVSTLLDQKICEFRGVCVFAPDRLRVNDTIYLQLRCFMRIEAFQPKELPQKQDDNRATTIFEQEESAEEKQLRLRQVALVQLFDEIGLKSTTQDDEIKKQRKEGLLRAAEMADQEAKKLAKSGNTDSGDEEPAELEQDQLDALYKKAQSFDFSMPEAQPPSSFAMDLRKYQKQALYWMLSKEKDKKSGREVSIHPLWEEYDWPLKDVDDKDLPIIEGINHFYVNPYSGELSLDFPAQEQHCLGGILADEMGLGKTIEMLSLVHSHRNLPPTQSLGNLTRLPVSGVVPAPYTTLVVAPMSLLAQWEGEALKASRNGSMKVLMYYGNEKNVNLREMCSAGNAAAPNMILTSYGVVMSEHRTHQALAPGTSWTPGNLFSVDFFRVILDEAHIIKNRRSKTARACYDLKATHRWVLTGTPIVNRLEDLFSLVRFLRVEPWNNFSFWKTFITAPFESKEVVRAISVVQTVLEPLVLRRTKSMKTPEGEPLVPLPKRTIRIEKVELIEQEREIYNHIYTRAKQTFNSNVAAGTLLKSYSTIFAQLLRLRQTCCHPILTRNKAIVADEEDAAAAADQDSDLKDDMDLQELINRFTATTSDAESSNEPPDPSMKFTAHALRQIQTESAGECPICSEEPMIDPAVTACWHSACKGCLKDYIQHQRDKGVQPRCFSCRADLNPQDIFEVVRYQSPNTTPTEQTPSSIGGDNVYSSSQPPPPPRISLRRINPLSPSAHTSAKIHALLAHLVRVPAGTKSVVFSQFTSFLDLIGPQLTKAGISFVRLDGTMAQKARAEVLAQFTKFETFTQEELDQAESTSAPSGLTPTPKTPKQSSSPSSPTVLLISLKAGGVGLNLTAASNVFMMDPWWSFAIEAQAIDRVHRMGQLRDVNVVRFIVKDSIEERMLRVQERKMGIAGSLGLMGEGNEEERRKERIEELRLLFE
What is the function of this protein?
Probable helicase, member of the UBC2/RAD6 epistasis group.  Functions with DNA repair protein RAD18 in error-free postreplication DNA repair.  Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats.  Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
What are the official names of this protein?
DNA repair protein rad5.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CINAL_MYCBO
Sequence: MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL32_THISH
Sequence: MAVQQARTTPSKRGMRRSHDALKNAALSIEPTTGEVHRRHHISPDGFYRGRQVIKAKEQDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LYS0_ECOLX
Sequence: MKKAKAIFLFILIVSGFLLVACQANYIRDVQGGTVAPSSSSELTGIAVQ
What is the function of this protein?
Lysis proteins are required for both colicin release and partial cell lysis.
What are the official names of this protein?
Lysis protein, Bacteriocin release protein, BRP, Protein H.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Targeted by SRP to the Sec translocon.
Protein: DADA_BURMS
Sequence: MRVVILGSGVVGVASAYYLARAGHEVTVIDREAGPALDTSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMWQMLRNCTTERYALNKGRMVRLAEYSRDCLQALRAETAIQYEGRTGGTLQVFRTQQQLDGAAKDIAVLREANVPFELLSSDELKKAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAEQLGVKFRFNTRIDALAVAGGKIAGVQCGGEMVRADAYVVALGSYSTNLVASLVKIPVYPLKGYSITAPIVDAAKAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGFDKRLRDARRGTLEMCVNDLFPGGGDTAKATFWTGLRPMTPDGTPIVGRTPVPNLFLNTGHGTLGWTMSCGSGQLLADLMSGKKPAIRADDLSVHRYLSETDGEHRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: SYDND_CHLCH
Sequence: MSNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQLVIQPEQQALFAEAEHLHNESVISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHPLPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLTAAVRRYLEEKNFTEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADRSPGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTDKPDLRIPLEIQDVTSLFVDSGFKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKELGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQGDVVFFGAGKWEVTCKIMGGMRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALDILAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPHGGIAPGLDRLVMILCDEQNIREVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKKEEKKG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLI1_SCHPO
Sequence: MNQANFLQELPNVLKRLETGLIIPQLKDILRVFGLRLSGTKAELITRIKQLIERIAIENNTTSWEALKKAIDGDVTSAVCILKYNTYQIYSAAAPIAPPSSASGNRSYSRPFAPVVHSRIRFRKSPFYDILEQFNAPFVVPACVGTRNTISFSFHVTPPALSKLLNDPKQYRVYLFSTPSETIGFGNCLMEFPTPQMELRINNQVAHANYRRLKGKPGTTNPADITDLVSKYAGPPGNNVVIYYMNSTKSYSVVVCFVKVYTIENLVDQIKSRKAESKEKIIERIKNDNQDADIIATSTDISLKCPLSFSRISLPVRSVFCKHIQCFDASAFLEMNKQTPSWMCPVCASHIQFSDLIIDGFMQHILESTPSNSETITVDPEGNWKLNTFDEPVESSEDEFVPKEKVIELSDGEGISTMANKSNDQPTRRASTHNSGPPAKRKRESLVIDLTISDDDENVATSTTESPSNATKENSLSRNVQSPNIDTAISNRSTNVRHGHPGFKDYTVENSPASRERSTSESAQSSVHMGYAGEGGLLSGALRAPSQQNNNNSNTQHSINLHTIVPSPYEPPLSVTPSTAITNLSIPESNRTNSSASSKSFTMNDLILPPLHLKNTTQTNNAHEDAQSSNLSQNHSLFYERIPQRPSYRIEKQNKGIYEDENEQSISAMPIPRAHPQLPKNLLSQTAGPLWDEQQDAQVDWNSELQSNNSYHNSGFEGTGNTFQSID
What is the function of this protein?
Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins.  Involved in the maintenance of the centromere and in telomere length.  Regulates recombination, via extension sumoylation, particularly within the heterochromatin repeats.
What are the official names of this protein?
E3 SUMO-protein ligase pli1, E3 SUMO-protein transferase plil.
What is the protein family that this protein belongs to?
Belongs to the PIAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHIE_BETVU
Sequence: MAAKIVSVLFLISLLIFASFESSHGSQIVIYWGQNGDEGSLADTCNSGNYGTVILAFVATFGNGQTPALNLAGHCDPATNCNSLSSDIKTCQQAGIKVLLSIGGGAGGYSLSSTDDANTFADYLWNTYLGGQSSTRPLGDAVLDGIDFDIESGDGRFWDDLARALAGHNNGQKTVYLSAAPQCPLPDASLSTAIATGLFDYVWVQFYNNPPCQYDTSADNLLSSWNQWTTVQANQIFLGLPASTDAAGSGFIPADALTSQVLPTIKGSAKYGGVMLWSKAYDSGYSSAIKSSV
What is the function of this protein?
This protein functions as a defense against chitin containing fungal pathogens.  This endochitinase also exhibits exochitinase activity, i. e.  it is capable of hydrolyzing chito-oligosaccharides, including chitobiose.
What are the official names of this protein?
Acidic endochitinase SE2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Intercellular fluid of leaves.
Protein: RS7_FRAP2
Sequence: MSRRNRAPKRDILPDPKFKSQVVAKFVNHIMLDGKKSIAEKIVYGAFDKIKAKDASANEVEVFEKALDSVSPMVEVKSRRVGGATYQVPVEVRPERRQTLGMRWIIDAARKRKESTMGDRVAAEILEAIEGRGAAVKKREDTHKMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS19E_ARCFU
Sequence: MATVYDVPADLLIKRVAERLKDMVAPPEWAKYVKTGVHKERSPEQDDWWYLRLASIFRRVYIDGPVGIERLRTFYGGRKRRGSKPPKFRKGSGAIVRNALHQLEQLGFVKKTREGRVVTPMGRSFLDKVATELKSELVSEIPALEKY
What is the function of this protein?
May be involved in maturation of the 30S ribosomal subunit.
What are the official names of this protein?
30S ribosomal protein S19e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: ACP_SHEON
Sequence: MSNIEERVKKIIVEQLGVKEEDVKPAASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYVSKNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_STRT1
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKMVDTAYEFVREAAANDAVILFVGTKKQAAEAVAEEATRAGQYYINHRWLGGTLTNWNTIKKRIARLKEIKQMEADGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVIYIVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDEIDVIIPANDDAIRAVKLITSKMADAIIEGNQGEDASADFQEAAAADSIEEIVEVVEGDNN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: UL03_PSHV1
Sequence: MPRQLLAHVCQVVPGNEHRAVRYEFVEKHGHAGPGLAVLRLRKVLPRFTRRDDIPQPSANLRRVPALAKQKHLQALLRLMRPGESRGLRAGHRHPIQRCVQVLAYVVRELAPAELAKRENHEHVIEPARVWRLVLLLPARTYVRAVRASLPQRVPASHIWHEAFVTEIYRGCLDTLRVGQTGEAQHIGDRWYFRIHKHSR
What are the official names of this protein?
Uncharacterized protein UL3.
Protein: OPGD_XANC8
Sequence: MQRRHFLKNAAAALAALGLPALPPWALAAKAVGLRRLGQPQPFDYAWLKGQARALAKAPYKSHKQVLPGPLESLNWDQYQSIRYRQDHALWADGNGKFQAKFFHLGLYFHTPVHIYDIVDGKAQQLAYDPAAFDYGRSGLGGKQLPKDLGFAGFRLNTRKDTDRDFSAFLGASYFRAVGKEGQYGQSARGLAIDTGTGGPEEFPDFIAYYLEQPADDSDTVVVYGLLDSPSVSGAYRFAITNGEVLVMDIDSALYPRKAIERLGIGPCTSMYQTGENDRRMDWDWRPEIHDTDGLAMWTGGGEWIWRPLCNPPHLRFNMFVDENPRGFGLLQRDRNFDHYQDDGVFYEKRPCLWVEPKSGWGKGSVQLVEIPTVDETFDNIVAFWNPQAKPQPGQELLMGYRLYWGAHPPASSPLAHCMATRTGLGGIVGQKRSHFSWRFAVDFAGGELAALAKDPKAKVEAVLQVSRGTTEIVSARPLHELKGYRAMFDLVPPDEGTQQIDIRLFLRANGKPLTETWLYQWTPPPASERKIY
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ADRB2_BOVIN
Sequence: MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity).
What are the official names of this protein?
Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane. Activated receptors are internalized into endosomes prior to their degradation in lysosomes. Activated receptors are also detected within the Golgi apparatus.
Protein: CTF8_HUMAN
Sequence: MVQIVISSARAGGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKIIHLEKPFAVLVKHTPGDQDCDELGRETGTRYLVTALIKDKILFKTRPKPIITSVPKKV
What is the function of this protein?
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.  Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DSCC1, RFC2, RFC3, RFC4 and RFC5.  The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA).  The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA.  It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression.
What are the official names of this protein?
Chromosome transmission fidelity protein 8 homolog, hCTF8.
What is the protein family that this protein belongs to?
Belongs to the CTF8 family.
Protein: MNTH_RALSO
Sequence: MFRLPALPRIPTAPFCPSEVRGCVAIPPDLPLWKKLLRFAGPGLLVSVGYMDPGNWATDIEAGSRYGYSLLFVVLLSSLAAMVLQCLSARLGIVTGKDLARLSRERYRPGAVRVQWLLAELSIVACDLAEVLGCALAFHLLLGVPILGGVALTALDTLIVLGLKGKNFRQLEAIVLGLILTIGLCYFVELALIRPHWPSVAGALVPSWQALSAREPLYLAIGILGATVMPHNLYLHSSIVQTRVVSETEPARREAVGLSRLDTIVSLSLALLVNGAILVLAAAAFHANGHQDVADIQDAHRLLEPIVGTAVAGVLFGIALLAAGQSSTFTGTIAGQILMEGFLELRIPCWQRRLATRALALIPAFVGVAMLGDHAIGRLLVISQVVLGFQLPFAMFPLIRMTGDRALMGTFANGRLTSAVAWCLFAVISVANLWLVWQVLAG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MCTS2_HUMAN
Sequence: MFKKFDEKESVSNCIQLKTSVIKGIKSQLVEQFPGIEPWLNQIMPKKDPVKIVRCHEHTEILTVSGELLFFRQRKGPFCPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAVTAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK
What are the official names of this protein?
Malignant T-cell-amplified sequence 2.
What is the protein family that this protein belongs to?
Belongs to the MCTS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_JANSC
Sequence: MARKLAAGNWKMNGVEADLAEVDALGEAVAAANCDVLLCPPATLIAPMAKRAGLMDLYVGGQTCHTAASGAHTGDVSAAMLADAGASHVILGHSERRADHGERSEDVAAQVTAAIDANLIAIICVGETEAERDANVTLNVVSSQLAGSIPTGATPAQIVVAYEPVWAIGTGRTPTLEQIAEVHDHIRSELAARRGSAANDIPLLYGGSVKPGNAAEIFAVSNVDGALVGGASLKASDFGGIIAALSAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANH_VIBCH
Sequence: MRFKNVKKTALMLAMFGMATSSNAALFDYNATGDTEFDSPAKQGWMQDNTNNGSGVLTNADGMPAWLVQGIGGRAQWTYSLSTNQHAQASSFGWRMTTEMKVLSGGMITNYYANGTQRVLPIISLDSSGNLVVEFEGQTGRTVLATGTAATEYHKFELVFLPGSNPSASFYFDGKLIRDNIQPTASKQNMIVWGNGSSNTDGVAAYRDIKFEIQGDVIFRGPDRIPSIVASSVTPGVVTAFAEKRVGGGDPGALSNTNDIITRTSRDGGITWDTELNLTEQINVSDEFDFSDPRPIYDPSSNTVLVSYARWPTDAAQNGDRIKPWMPNGIFYSVYDVASGNWQAPIDVTDQVKERSFQIAGWGGSELYRRNTSLNSQQDWQSNAKIRIVDGAANQIQVADGSRKYVVTLSIDESGGLVANLNGVSAPIILQSEHAKVHSFHDYELQYSALNHTTTLFVDGQQITTWAGEVSQENNIQFGNADAQIDGRLHVQKIVLTQQGHNLVEFDAFYLAQQTPEVEKDLEKLGWTKIKTGNTMSLYGNASVNPGPGHGITLTRQQNISGSQNGRLIYPAIVLDRFFLNVMSIYSDDGGSNWQTGSTLPIPFRWKSSSILETLEPSEADMVELQNGDLLLTARLDFNQIVNGVNYSPRQQFLSKDGGITWSLLEANNANVFSNISTGTVDASITRFEQSDGSHFLLFTNPQGNPAGTNGRQNLGLWFSFDEGVTWKGPIQLVNGASAYSDIYQLDSENAIVIVETDNSNMRILRMPITLLKQKLTLSQN
What is the function of this protein?
Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources.  Sialidases have been suggested to be pathogenic factors in microbial infections.  Facilitates cholera toxin binding to host intestinal epithelial cells by converting cell surface polysialogangliosides to GM1 monogangliosides.
What are the official names of this protein?
Sialidase, Neuraminidase, NANase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQ75_SCHPO
Sequence: MSYYYETEEVNNNPELKSNFPWLADRIHEGRSSIFHALGYVGLKTENAFGWFLSTERKTISTAKNEVFSSDERKLPGVAYVVVGGMAGNIFARNRIAPARWLITSLSTAATFMFCFPKTSKNIGAFVEKRFPAIRKQRMLVLEQTQKNIQNAQKSMTSAVEGVQKHYENAVKKIKGD
What are the official names of this protein?
Uncharacterized protein C1442.05c.
Protein: FOLD_STAAW
Sequence: MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKIGMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQKNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLKGDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MSD4_AMAPH
Sequence: MSDINGTRLPWLATCPCVGEDVNPTLSRGER
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24613547).
What are the official names of this protein?
MSDIN-like toxin proprotein 4.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: HIS3_CLOB1
Sequence: MNLQKISKKIDFKKGAGLIPTIIQDFCSGEVLMLAYMNKESLEKTIETNTTWFWSRSREELWNKGATSGHFQYVKSIHIDCDGDTLLIKVEQLGPACHTGNRSCFYTTLI
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_ERYLH
Sequence: MIIGLGSDLCNIERIQNSLDRFGERFENRVFTEIERAKARRRPFTIAGTYAKRFAAKEAFSKAVGTGFRRGVFMKDIGVVNARSGAPTLALTGGAAIRLAELLPDGHEASIHLTLTDDHPWAQAFVIIEAHRI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAP_CERS1
Sequence: MTLDLDALDRALDALPNLFRGPGGVAGVVKDGQVVASRAWGYADLTRRRPMETGTRLPICSISKQFTCGVLLDTLGDTAAYDARVAEFLPQFEGPLPTLRQLCDNQSGLRDYWALTVLQGAEATQTFRREDALPLIARMKTGHFPPGTAYSYCNCNFRIVSEILESETGRALPDLYAERIFGPAGMRTAELTSDTRHPADEVVGYEGSDAVGFFPADNGIFWIGDAGISASLQDMLAYESWIDATRDDENSIYRRISVPPAYVCGTPASYGFGLSHETVAGLKVTGHGGALRGFRAQRFHAADERLSVVVIFNHEASAHAAASSLLAAALGHEAPKGAGPEGWAGQWLDPESGLLLRVGEDAEGLTLRFATGPDRLTVGEDGVPRGAGVSLAREGATLVMNRTSDNLTVRAEPLPVVAVADAGEIAGRYHARELEADLVIEARDGGAYAGFEGLLGAGPMERLHPVGPDVWIVTTRRSMDAPAPGDWTLQVRREGGAVAGLRLGCWLARRIDYARV
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
Protein: LRGA_STAAM
Sequence: MKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LOC1_KLULA
Sequence: MAPKQSKTAKRSKKQNGTREVRSEVFEDSIAKNQMANVPKMTEKSDTKKPTKLQVKKDNFKARLYGSQKKKERRYTEKELNIPTLNRAIVPGVKIKKGKKGKKFIGDHDLIALNRLIKTIGDKNDEITESKLEKTRRLEEIRDLKRQEMERKETEKKEQLEGKKDEIKKKASVARTIRRKTKRQELKQETLAAQSEPIKKKKSVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein LOC1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CDUB1_CHLTS
Sequence: MLSPTNSTSKTAPVPPQDSSKPVLISEEPQNQLLQKVARTALVVLLVVVTLGLILLFYSFSDLQSFPWCCQTRPSTKEQPTISIPVPLPSPPLAVPRPSTPPPPVISRPSMPPAPTPAISPPSTPSAPKPSTPPPLPPKAPKPVKTQEDLLPFVPEQVFVEMYEDMARRRTIEALVPAWDSDIIFKCLCYFHTLYQGLIPLETFPPATIFNFKQKIISILEDKKAVLRGEPIKGSLPICCSEENYRRHLHGTTLLPVFMWYHPTPKTLSDTMQTMKQLAIKGSVGASHWLLVIVDIQARRLVYFDSLYNYVMSPEDMEKDLQSFAQQLDQVYPAYDSQKFSVKIAAKEVIQKGSGSSCGAWCCQFLHWYLRDPFTDALNDLPVDSVERHENLASFVQACEAAVQDLPELFWPEAKALF
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease possesses deubiquitinating and deneddylating activities (By similarity).
What are the official names of this protein?
Deubiquitinase and deneddylase Dub1, ChlaDub1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Secreted. Host cell. Membrane; Single-pass membrane protein. Note=Secreted, and delivered into the host cell.
Protein: BVCP_NPVOP
Sequence: MVYRRRRSRSADGTYTRRRRSSGYRRRPGRPRTYRRSRSATRRSGYRRRRY
What is the function of this protein?
Thought to be responsible for DNA condensation during packaging of the nucleocapsids.
What are the official names of this protein?
DNA-binding protein, Arginine-rich protein 6.2 kDa, Basic viral core protein, Nucleocapsid protein.
What are the subcellular locations of this protein?
Virion.
Protein: UPPP_HAHCH
Sequence: MTWLEIVVLALIQGLTEFLPISSSAHLILPSEVWGWQDQGLAFDVAVHVGTLLAVMVYFRADIFNLLNGWIKQITGGGASQESRLAWAVILGTIPACVAGLLLDSWIEENLRSALVIALTTIGFGVLLGMADRKEGTRDIDQFTLKDALIIGVSQALALIPGTSRSGITMTSALFLGLNRDTAARFSFLLSIPLIAAAGLFKGLELADTGTSSQWSEIAGATLISAVSAYACIHLFLKFLQKIGFMPFVIYRMLLGAGLLVWLYVA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.