PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_I78A7
Sequence: MKTIIALSYIFCQVFAQNLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDNPHRILDGKNCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFFNEGFNWTGVTQNGGSYACKRGPDNSFFSRLNWLYKSESTYPVLNVTMPNNDNFDKLYIWGVHHPSTDKEQTNLYVQASGRVTVSTKRSQQTIIPNVGPRPWVRGLSSRISIYWTIVKPGDVLLINSNGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SYI_SULIM
Sequence: MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTIWNKVIKDCILRYERLLGKKVHDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFINKCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAVLHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVNKDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSAQTKLDDFHQVVDAGNVVTLTDGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEEGGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCWRCKTPLVLRAIDQWFIRVTKIKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVGSREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKDWQEKWKELGPVDLVLEGHDQLRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHKSLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRALELTKRDLQIIWNTYVFASMYMNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVEDVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNPKESVSMESSINYDERFIDNELERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDEDTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEPNRSIIGKEYKSMSPKILDYIRNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEISESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNKVILGDPKGDIVMDWDIEGESYIIGIKKST
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG_ECO81
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSX1_BOVIN
Sequence: MAPAADMTSLPLGVKVEDPPFGKPAGGGGGQTPSTTAATAAAMGADAEGAKPKVSPSLLPFSVEALMADHRKPGAKKSVLAASEGAQAAGGSAKPLGARPGSLAAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQNPRFSPPPSRRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPATFGLSFPLGGPAAVAAPAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FER3_MAIZE
Sequence: MSTSTFATSCTLLGNVRTTQASQTAVKSPSSLSFFSQVTKVPSLKTSKKLDVSAMAVYKVKLVGPEGEEHEFDAPDDAYILDAAETAGVELPYSCRAGACSTCAGKIESGSVDQSDGSFLDDGQQEEGYVLTCVSYPKSDCVIHTHKEGDLY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-3, chloroplastic, Ferredoxin III, Fd III.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVD_MYCTU
Sequence: MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVEVVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTIIDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMSDVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGFDSDVFEGTARVFDGERAALDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFASRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.  Is specific for the (R) isomer of 2,3-dihydroxy-3-methylbutanoate, with no catalytic activity against the (S) isomer.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: BETA_XANCP
Sequence: MQREYDYIIIGAGSAGNVLAARLTEDPGVSVLLLEAGGPDYRLDFRTQMPAALAFPLQGRRYNWAYETEPEPHMDNRRMECGRGKGLGGSSLINGMCYIRGNALDFDHWAKRPGLEDWGYRDVLPYFRKAETRDIGANDYHGGEGPVSVATPKNDNNVLFQAMVDAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDMAKPRDSLHIVTHATTDRILFAGKRAVGVHYLVGNSSEGIDAHARREVLVCAGAIASPQLLQRSGVGAPDLLRALDVQLVHDLPGVGQNLQDHLEVYMQYACTKPVSLYPALQWWNQPAIGAEWLFAGTGTGASNQFEAGGFIRTREEFDWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRTPSRGRVHARSRDPRQHPSILFNYQSTDQDWQEFRDAIRITREIIAQPALDPYRGREISPSADCKTDAELDAFVRARAETAYHPSCSCAMGTDDMAVVDGQGRVHGMEGLRVIDASIMPRIITGNLNATTIMIAEKIVDRIRGRAPLPRSTADYYVAGDAPVRR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: VP7_ROTS1
Sequence: MYGIEYTTVLTFLISIILLNYILKSLTRIMDCIIYRLLFIIVILSPFLRAQNYGINLPITGSMDTAYANSTQEETFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSVYFKEYTNIASFSVDPQLYCDYNVVLMKYDATLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDATTFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGSDILDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVDQIIQVMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved (By similarity).  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors (PubMed:12941907).  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7 (By similarity).
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: OBG_ECO27
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MARH9_MOUSE
Sequence: MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGGGGGCGWAPFAGCSARDGDGDEEEYYGSEPRARGLAGDKEPRAGPPPPPAPPPPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIVHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDVGGDTGGGAAGKPGPRTSRTSPPAGAPTRPPAAQRMRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV
What is the function of this protein?
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF9, Membrane-associated RING finger protein 9, Membrane-associated RING-CH protein IX, MARCH-IX, RING-type E3 ubiquitin transferase MARCHF9.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: YIDZ_SHIB3
Sequence: MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSRELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHETWNLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SYDND_CHLTR
Sequence: MKYRTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQIVCRQEENPELHQLMDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRAQNLPFSISDEHINVNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGKSTPEGARDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQPEFTQIDMEMSFGGPEDLFPVVEELVARLFAVKGIELKAPFLRMTYQEAKDSYGTDKPDLRFGLRLKNCCEYARKFTFSIFLDQLAYGGTVKGFCVPGGADMSRKQLDIYTDFVKRYGAMGLVWIKKQDGGVSSNVAKFASEDVFQEMFEAFEAKDQDILLLIAAPEAVANQALDHLRRLIARERQLYDSTQYNFVWITDFPLFAKEEGELCPEHHPFTAPLDEDISLLDSDPFAVRSSSYDLVLNGYEIASGSQRIHNPDLQNKIFALLKLSQESVKEKFGFFIDALSFGTPPHLGIALGLDRIMMVLTGAETIREVIAFPKTQKAGDLMMSAPSEILPIQLKELGLKL
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 111R_IIV6
Sequence: MILVLLLILIAFLYIYFPSSLNQKNQELSTLSKNLINNYSFVPKTFKQKIHIIIPLKSNVDNIIHNILKQTEKVDIMTIIVPKEYENKLKNGKNSLCKLLRDTCIIQISGGYGMLSKERETGTILVYVNNLFSDPNTLKNMLNRISKSTKKIFYFSDATVIDNSIPIGIDDAYKL
What are the official names of this protein?
Uncharacterized protein 111R.
Protein: CCGL_MOUSE
Sequence: MTAIGAQAHKLLGLKRPHRSFFESFIRTLIIVCTALAVVLSSVSICDGHWLLVEDHLFGLWYFCTIGNHSEPHCLRDLSQAHMPGLAVGMGLARSVAAMAVVAAIFGLEMLIVSQVCEDVRSRRKWAIGSYLLLVAFILSSGGLLTFIILLKNQINLLGFTLMFWCEFTASFLFFLNAASGLHINSLTQPWDPPAGTLAYRKRGYDGTSLI
What is the function of this protein?
Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).  Modulates calcium current when coexpressed with CACNA1G.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-like subunit, Neuronal voltage-gated calcium channel gamma-like subunit, Transmembrane protein 37.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPG_VIBAL
Sequence: MAGAKEIRNKIGSVKSTQKITKAMEMVAASKMRRSQDAMEASRPYAETMRKVIGHVANANLEYRHPYLEEREAKRVGYIIVSTDRGLCGGLNINVFKKAVTDMQTWREKGAEIELAVVGSKATAFFKHGGAKVAAQVSGLGDNPSLEDLIGSVGVMLKKYDEGELDRLYVVFNKFVNTMVQQPTIDQLLPLPKSDSEEMQREHSWDYIYEPEPKPLLDTLLVRYVESQVYQGVVENLACEQAARMIAMKAATDNATNLIDDLELVYNKARQAAITQELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZAPA_ECOSE
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: PAX1H_CAEEL
Sequence: MNCDTAQPWMMSSYHPSTTSDVFWTTTPSSTSTTPSSDNGIQQYSSISTSSGYAPANSPAKTAEVNQLGGVFVNGRPLPFEMRCKIVELSRQGTRPCDISRQLKISHGCVSKILTRFSENGTIMPGTIGGSRPRVTTPKVVEYIRSLKRSDPGIFAWEIRDRLISADICDRANLPSVSSISRILRNKNGGNSSSSSSSQLRYIRDQLAEQQQQQHLQQHQYMEYNNNELNQISGNLDYQVSSSNTPPSYDSYHFIAN
What is the function of this protein?
Transcription factor (By similarity).  May play a role in pharyngeal cell differentiation (Probable).  May have a protective role in response to infection by the Gram-negative bacterium Vibrio cholerae (PubMed:22675448).
What are the official names of this protein?
Paired box protein 1 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUF1_ARATH
Sequence: MAIFKDCEVEIFSEEDGFRNAWYRAILEETPTNPTSESKKLRFSYMTKSLNKEGSSSPPTVEQRFIRPVPPENLYNGVVFEEGTMVDADYKHRWRTGVVINKMENDSYLVLFDCPPDIIQFETKHLRAHLDWTGSEWVQPEVRELSKSMFSPGTLVEVSCVIDKVEVSWVTAMIVKEIEESGEKKFIVKVCNKHLSCRVDEAKPNMTVDSCCVRPRPPLFFVEEYDLRDCVEVFHGSSWRQGVVKGVHIEKQYTVTLEATKDKLVVKHSDLRPFKVWEDGVWHNGPQQKPVKESPSNAIKQKPMCSSSGARPMTPKMATKHARISFNPEENVEELSVAETVAATGKLEKMGIAEESVSCVTPLKQTEANAEGNKLEPMRNQNCLRNDSTQQMLPEEENSKDGSTKRKREEKHNSASSVMDEIDGTCNGSESEISNTGKSICNNDDVDDQPLSTELPYYQSLSVVNSFAADAEETPAKSARTISPFAKKLPFWKSYETDELYKSLPQSPHFSPLFKAKEDIREWSAVGMMVTFYCLLKEVKDLQLDDSSSKLSSLSSSLAELEKHGFNVTDPLSRISKVLPLQDKRAKKAEERKCLEKKIECEEIERKRFEEEFADFERIIIEKKRQALVAKEKKEAADKRIGEMKTCAETIDQEIKDEELEFQTTVSTPW
What is the function of this protein?
May be involved in the polar growth of plant cells via transportation of RNAs.
What are the official names of this protein?
DUF724 domain-containing protein 1, AtDUF1.
Protein: Y4449_ARATH
Sequence: MVTPSLRLVFVKGPREGDALDYKPGSTIRVGRIVRGNEIAIKDAGISTKHLRIESDSGNWVIQDLGSSNGTLLNSNALDPETSVNLGDGDVIKLGEYTSILVNFVIDDFQEKKLTRNNRRQANARKRIRVLESINLGDITEEEKGLDVKFENKPSSRVRKVRKIEDSEKLGITDGLQEDLVEKNGSFRNVESIQSSSVNLIKVEMEDCAMVEENLGRGLKKRVSSKATRSKKIEESVGKACLGVVNVEKVETLKEKRITRATRSKKIDIVGDSYLELDMVLNRARKNKGKNKKADQKPLKSFENDEVTDSGEQGLSCHVEEDMNNELDTDLRKMTLGALFSFLEGHLSKEIIHKTENMIEPMRSKTQRVREYISDQRKVQAKACMC
What are the official names of this protein?
FHA domain-containing protein At4g14490.
Protein: DNAA_COXBU
Sequence: MSLPTSLWDKCLGYLRDEIPPQQYNTWIRPLHAIESKQNGLLLLAPNRFVLDWINERFLNRITELLDELSDTPPQIRLQIGSRSTEMPTKNSHEPSHRKAAAPPAGTTISHTQANINSNFTFDSFVEGKSNQLARAAATQVAENPGQAYNPLFIYGGVGLGKTHLMHAVGNAILRKDSSKKVLYLHSERFVADMIKALQHNAMNEFKRFYRSLNALLIDDIQFFAGKDRSQEEFFHTFNALLDGQQQIILTCDRYPKEINGLEERLQSRFGWGLTVAIEPPELETRVAILMSKAEQLKVHLPHEVAFFIAKHIQSNVRELEGALKRVIANAHFTGQSITVDFTREALKDLLTLQARLITIENIQKTVAEYYKIKVADLLAKRRNRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVKELLATSLDILEDYKNLMRILSG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP39_NPVOP
Sequence: MALVSPGVSSRRSTNHCIFGAIEPFDSCVTYRSPCSSDASVDDGWFICDYHLKLRFKMSKMVLPIYDEDDNQYKRTIARHLVGHKERGVKRILVPTRANYMTVFNLPGMMLAEQLIFHLIYDNRLEVNRICASLKNNENFIDNTYSVVESVYSATRNILSLTDPQAYCSRVANDDVRFFDANVVDNNYQAGNGDTVFNNMPGFLRNLIRRAVAPETLQIDSEDLRLRNCNTCVINNTGLVATVTNTELYNPVRSSDIIKTRPNRLQIRNVLKFEGDTRALERTLGRYEEYPMYVPLFLGYQLVNLQNDILRANNFLPAPFGVPQAVNNLEAQAPAAPAPAAPAPAPAAPVV
What are the official names of this protein?
Major capsid protein.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p39 family.
What are the subcellular locations of this protein?
Virion.
Protein: UXUA_YERPA
Sequence: MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRVRLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRPILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: SH3B4_RAT
Sequence: MAAQRIRAANSSGLPRCKSEGTLIDLSEGFSETSFNDVKVPSPSALLVDNPTPFGNAKEVIAIKDYCPNNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELDLLGGWTDDQKQSGRPYSNNPFWNGVRTNPFLNGNAQPSMDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFDELPATNGIHLEQPVKRDNPFFRSKRSYSLSELSVLQAKSDAPPTSSFFTGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGSVQLPDTSISIHVPEGHVAPGETQQISMKALLDPPLDLNSDRSTSISPVVEVKLSNLEVSTFIILEMKVSAEVKGDIFSKSTVVLQCLRSDSKEGPYAPIPLAYSYGDTIQVQLDNLEPCMYLAIVAQGSNILYPSTVWDFIHKRVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVTEVTRQAPSPAPVALQLWGKHQFILSRPQDLRVCMFSNMTNYDVKSNEQAKVVRGFQMKLGKVSRLIFSVISQNPNELSDFTLRVQVKDDQDTILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFVVTTKYPTFQDRPVSSLKFGKLLKTVVRQNKSHYLLEYKKGDVVALLSEERIRLKGQLWTKEWYIGYYQGKVGLVHTKNVLVVGKARPSLFSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRAFADALGYGNLPLTFFCRAELDSEPERVASVLEKLKEDCNNPDNKDRKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHIGLDKMKNPITRRWKHLTGTLILVNSLDILRAAAFSPADHDDFVI
What is the function of this protein?
May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis.  Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes.  Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation.  Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
What are the official names of this protein?
SH3 domain-binding protein 4.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Specifically associated with transferrin receptor- containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus (By similarity).