PharMolix/UniProtQA huggingface dataset:
Protein: RL7_LEGPL
Sequence: MAVSKNEILETISNMTVMEVVELIEAMEEKFNVSAAAAAVAVAAPAAGAGAAAAEEQTEFTVVMTSFGSNKVNVIKAIRGITGLGLKEAKDLVEGAPSTVKEGVSKDEAASIKKELEEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GLMM_PSEMY
Sequence: MARKYFGTDGIRGRVGQFPITPDFMLKLGWAAGMAFRKEGKCRILIGKDTRISGYMFESALEAGLAAAGADVQLLGPMPTPAIAYLTRTFQADAGIVISASHNPHDDNGIKFFSNEGTKLPDDVEAMIEELLDQPMTVVESAGIGKASRINDASGRYIEFCKGSVPSGTSFKGLKIVIDCAHGAAYKVAPSVFRELGAEVRVISAQPDGLNINDGCGSTHIAALQAEVVAQQADLGIAFDGDADRVLMVDQYGAVVDGDELLFIIARDLQERGRLRGGVVGTLMSNLGLELALAELNIPFVRAKVGDRYVIAELLARNWQLGGENSGHLVCFQHTTTGDAIIAALQVLMALKRRGQSLVEARSDLKKCPQVLVNVRLSGAVDPLEHPSVKEACARVTERMAGRGRVLLRKSGTEPLVRVMVEGDEESSVRGYADELAKIVAEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RNH2_FRATT
Sequence: MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLKAMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKEHLENIKKYGVLDIHRKSYKPVQVLLNE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U160_DICDI
Sequence: MSDLTICTHSGSFHADEALACYLLKLLPTYKDSKIIRSRDKSVIEKSTVAVDVGAVYNFEKLRFDHHQSGFTETFDDKHDIKLSSAGLIYKHYGKDIIKQRLDTNDSITELLYQKLYDSMIQELDGVDNGVERYPSDIKPRYQSGSSISARVGHLNQGWNEPQDDEIVNKQFEKAMELMGQYFLDRLDYYGKSWLPCRSIVENALENRKQTHSSGEILILDMFCPWKDHLFSLEQEKDIKTPIKFVLFEDTSGQWRVSAVGINLHSFTLRLPLPEEWRGKRDEELSQISGIEGCVFAHANGFIGGNKTREGALLMAIKTLNQSPKTLLE
What are the official names of this protein?
MYG1 protein.
What is the protein family that this protein belongs to?
Belongs to the MYG1 family.
Protein: YAEP_ECOLU
Sequence: MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: STP2_CANAL
Sequence: MSVAITSNNNKQPQPQPQPHLKVVNNNSTFNLYTWLRSVFQYCISLIISYTSNWLLVNNDNNNNNININYKSNNNDNNNASTSLQPKISNVKAESMKIFPDLQKSNFTTYYTTEKPLHQDVLKPVICSTGITSRILPYTNEKGELEWKFTEVQGKELDEFKMHPQQQQQQQEVKQELSPAESNESNESLAKDSSTTPASISDSPSHSETESTVSSTIIANSNQIFKCPSCDAEFRVRGYLTRHMKKHSTKKAYTCPFHDKSIYVDENNITHKCHSSGGFSRRDTYKTHLKSRHFNYAKPIKSAERSKVPGQCAMCGEHFNSAEIWCEIHVEGGECKFLPMGFKGKSRIKNRLKKQIQKNKMIDPELVPFASKVLEEVEQERQKKKNYRTTGTGSESSIQSQESESSINSTPLSMQISAPVPMPVSIQQQHQHQHQHHHHVQNQHQQHVNQQQSIATPASIYSSSASSTSSYESTHSPYTPQSSRSPLSHMYNPQQPPYFNQIAQAHQQDGQKNQVKDDYDDEYCLDVDQLNTTFVNETVANYLQIHDFHSMNQYQPGQQQQQQQQQQQQQQQRQHQQQQPSMYF
What is the function of this protein?
Transcription factor involved in the regulation of gene expression in response to extracellular amino acid levels.  Synthesized as latent cytoplasmic precursor, which, upon a signal initiated by the plasma membrane SPS amino acid sensor system (including CSY1 and CSH3), becomes proteolytically activated and relocates to the nucleus, where it induces the expression of SPS-sensor-regulated genes.  Required for efficient alkalinization through the release of ammonia from the cells produced during the breakdown of amino acids, and subsequent switch to the hyphal form.
What are the official names of this protein?
Transcriptional regulator STP2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Localizes to the cytoplasm in its unprocessed form and is targeted to the nucleus after proteolytic processing upon induction by amino acids.
Protein: SYS_RHIEC
Sequence: MLDIKWIRENPEALDAALAKRGAEPLAQTLVALDEKRRSAVQKTQDLLSRRNAASKEIGAAMAQKNAELAEKLKAEVAEIKETLPAAEEEERTLSAELIDALSRIPNVPFDDVPVGKDEHDNAVARIVGEKPRWNHTPREHFEIGEALGYMDFERAAKLSGSRFTVLTGPLARLERALGQFMIDLHTREHGYTEVSSPLMVRAEAVFGTGSLPKFEEDLFKTTDGRYLIPTAEVTLTNLVREEILDQEKLPLRFTALTPSFRSEAGSAGRDTRGMLRQHQFWKCELVSITDAESSIAEHERMTACAEEVLKRLGLHFRTMTLCTGDMGFGSRKTYDLEVWLPGQNAFREISSCSVCGDFQARRMNARYRGKDDKNNKFVHTLNGSGTAVGRCLIAVLENYLNEDGSVTIPDVLLPYMGGLTKIERAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_BMDNV
Sequence: MPIWGAISSNDLLNTYYTIEESQQIVEELLDFQMHNDQLEYFDSIEDAKKRFITDLYEILEKKHQKTNTFQIVSPPSAGKNFFIETVLAFYWNTGVIQNFNRYNNFPLMEAVNRRVNYWDEPNFEPDATETLKKLFAGTSLKATVKFQKEANVQKTPVIITANYDKFTKEVWDDRIIKYYWYPCPKLKEYNKRLHPFAWVYLIDKYVTDLLILIKMYNHRVMGNKICNLIKMYKYRVMVINIFSAFICLILIFLTNNYLGPGLYTCKSIDETTLSEAVVIWPSDKVTNHKEVFQADKQARDEFFTSFVHIGNVHSLIGGIGLGTKNLVEEHVLGKPLYGMGKRKSTEKDWAKIKRINRARAARRENQENQPDIREFGHVAGQNINADQEVNLADFPDFLQDFDAEAGPSGTQPVETAQQSPPTMSEDIQPMETVGATDTGGGAQVDPRTGGQAAGGSEMGAGGSANDGREDIFSGAPQPNQHHTLVYGKSYHFTITKWFTEFRHLATTNSGYYAQQRFKHIHGIPWERLLMYVSEGELLRMFRDYTSLKVEEVVCEVYSLGVRLPFVTSATTSSVANANAQYPIDVFHFDEAYETNYGINNVADIINKALGTEWKNATRPTAPVTTAWSEQFPNISASSTSRDINNPVIVDYSLPYFENNVPKDVGIYDYVDIKNGTTAYGKCWEKRFKPTNGLLYAESTLKGNVVTPLAAPTNIMTPIPGLENGYFMSNDQIRERRDLTTSVPPDALTATKLNQSASNNLNAFVDYMGYNYFGEQKAPQSMPKFMIGFVNIRNEDNSLLNAKWDILIKTRIRLTGLQSTREWVARTDRIPPQYFTSQYTQFRYPNINDTPLLRSLGTFKLPTKRPGMDSRIALGELQKQRKMNL
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication.  Also plays a role in viral packaging and transactivation of several promoters.  Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR).
What are the official names of this protein?
Initiator protein NS1, NS1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TDA11_KLULA
Sequence: MDRDVLEKFIDLQDKENDIDTKSKIYHEVTDRGSVTPTFNQGSSGMSPKSVGSSGRNKNIQLQLTPTKADPTSTLDSHPLKGDNSDQDDITGNMKENEDDVSLGSGKVTVKNNGNGVSAATNGKGGNQELGIRRSNTWKRKSLIMPLMSPEHTVKQQQRQSYQQHCKPSESVSNTPLGRKYRSKLDRNDGQKSVRSSISSIGSLLPDGATTEFSASPATKLKLPTTTTDTAKVVPSVSEDDNDMESLLQSLANKELEILERTRRVHDLFRQIKIEDKIIKQNAEELQQLKKKVSRLVGNQVQGQNSNTTLPAESHGESNNAETADNKSSSLWTKSVSLLNQFDQIIQGTVETKLGLGDSGSSATENQSEGKPKGDDNAGSAIWSLVNEFKNGLGLLATEEEDADGSIGTIATGLATNMEDYGTRKAESSTQAKEIEMYHYSH
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VFH33_ASFB7
Sequence: MAGRVKIKQKELIDSTVKNKNVMNLFHEIIGSKGNINFSVVWPKFKKIKQSVYDYISTLSVLEKASVMQNFEADKKLLELFVQKLWAAYEGYFKYPEIEKYEVEGQVNFNLVPQCVLEKFSQLYRIRINSELVTLILNSCAFMSKYNDYILKKDPYILTITPGLCFSPIPNFEDLNFKHLYNSDKNSQHDKEFIMFILYKLYTAALGVYNAISIPDIDVEDLENIILSSVSQIKKQIPRCKDAFNKIESSVHLLRKNFNTYYSDYVGSGYNPTIIMEQYIKDISQDSKNISPRISYQFRTIIKYYRDMIATRHQTMDPQVLNLVKHVEKKLDMLDREKN
What are the official names of this protein?
Protein H339R, pH339R, Protein j4R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H339R family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion.
Protein: DPYL3_HUMAN
Sequence: MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
What are the official names of this protein?
Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4, Unc-33-like phosphoprotein 1, ULIP-1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Protein: PSRP_XANC5
Sequence: MSTIRPVFYVSDGTGITAETIGHSLLTQFSGFNFVTDRMSFIDDADKARDAAMRVRAAGERYQVRPVVVNSCVDPQLSMILAESGALMLDVFAPFIEPLERELNAPRHSRVGRAHGMVDFETYHRRINAMNFALSHDDGIALNYDEADVILVAVSRAGKTPTCIYLALHYGIRAANYPLTDEDLENEQLPPRLRNYRSKLFGLTIDPERLQQIRQERRANSRYSAAETCRREVAIAERMFQMERIPSLSTTNTSIEEISSKVLSTLGLQREMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: FEOC_ECOSM
Sequence: MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: RUVB_CHLL2
Sequence: MRIELLNTPADALETRFEEQIRPIRMLDFAGQQRLTDNLRVFISAAKMRGDALDHVLLSGPPGLGKTTLAHIIAAEMGSSIKATSGPLLDKAGNLAGLLTGLQKGDVLFIDEIHRMPPAVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATTRSGLLTSPLRARFGINSRFDYYSADLLEKIIIRASGILGIGVDQDAAAEIAGRSRGTPRIANRLLRRARDFAQVADAPLITRSIAMTTLDCLEIDEEGLDDMDKKIMDTIVNKFSGGPVGAASLAVSVGEEQDTIEEVYEPYLIQAGYIARTPRGRVATRRALLRFSVQESRGDGPLFEFPLEDDQRQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DDL_BURCJ
Sequence: MSGIDPKRFGKVAVLFGGESAEREVSLTSGRLVLQGLRDAGVDAHPFDPAERPLSALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGVPTPPFETVMRGDDLAARATDIVAKLGLPLFVKPASEGSSVAVLKVKTADALPAALEEAATHDKIVIVEKSIEGGGEYTACIAGDLDLPLIKIVPAGEFYDYHAKYVADDTQYLIPCGLPAQQEAELKRIARRAFDVLGCTDWGRADFMLDAAGNAYFLEVNTAPGMTDHSLPPKAARAVGISYSELVVKVLSLTLND
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRIL_HORSE
Sequence: MSSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHFFRELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAIVLEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTNIQRLVGSQAGLGEYLFERLTLKHD
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin light chain, Ferritin L subunit.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: GRPE_BACC2
Sequence: MEERNEQVVEEVKEAQVEEAVTPENSEETVEEKSEAALLQEKVDELQAKLTETEGRTLRLQADFENYKRRVQMDKQAAEKYRAQSLVSDILPALDNFERAMQVEATDEQTKSLLQGMEMVHRQLLEALTKEGVEVIEAVGKQFDPNEHQAIMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_LATSS
Sequence: MSLKEQLEHLQQKSLQDIQKVVDLDALNQIRVEVLGKKGPITEVLRGMRDLSNEERPKVGAFANEIKSDLAQAIEARKAELEAKKEAAQLAHETIDVTLPGQPVKKGTPHVLTQVIDDLEDLFIGMGYQVVAGFEVEDEKHNFEMLNMPADHPARDMQDTFYITKDTLMRTHMSPNEARDLESHDFANGPIKMISPGRVYRRDTDDATHSHQFYQMEGQVIDKNITMADLKGTLEYTIHHIFGEDRDLRFRPSYFPFTEPSVEVDISCFRCNGEGCSVCKQTGWIEVLGAGMTHPNVLKAGGVDPEVYGGFAFGLGIDRFAMLKYGVDDIRNFYLNDVRFLNQFTQEV
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAJ_SOYBN
Sequence: MRDLKTYLSVAPVVSTLWFGALAGLLIEINRFFPDALIFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CBG50_UNIPI
Sequence: KDALEHTGFAPKKDGEEHVEWNYN
What is the function of this protein?
Calcium-binding.
What are the official names of this protein?
Calcium-binding shell glycoprotein P50.
Protein: PPID_HUMAN
Sequence: MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGHTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAECGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDKEKAVYAKMFA
What is the function of this protein?
(Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, 40 kDa peptidyl-prolyl cis-trans isomerase, Cyclophilin-40, CYP-40, Cyclophilin-related protein, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
Protein: TRM1_PYRFU
Sequence: MSMELFEVHEGKAKVLVPKAKTIYDSPVFYNPRMAPNRDVVVLLLNVLKPKIVLDALSATGIRGIRFALETPAEEIWMNDINELAYELMKKNVLLNFKGTLKENAKRAIFEGEKTIVINNDDANRLMAEKHRYFHFIDLDPFGSPMEFLDTALRSVKRKGILGVTATDGAPLCGAHPKACLRKYLAVPLRGELCHEVGTRILVGVIARYAAKYDLGMEVLLAYYKDHYFRAFVKLKDGAKKGDETLENLGYVYFDEKTGRFEVEKSFLSTRPNAYGPLWLGPLKNEKVVGEMLELLVSGFEVANYREVLKLLHMLHEELDIPLFYDTHALGKRLKIEPKKLGEIIKELKSMGYEATRTHFSPTGIKTNAPYEVFVEVMRKN
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RN145_CAEEL
Sequence: MEGVMENVGGLMQNIRRRHMSITEMTEESVRLGVAQMDTGFKKIKEMSIMVLETGLRLPGLLFIELLWRYQGFSFEDISDDMMKQTPLSYFDIPTMLDFVHRRNFDHHAAIILSYFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAYKLSAIYVDLEMKTGEEELKLDGLIKLERHGFHFLAQMLLVVLQSMLLEVDGEPWRVALPVFALPIVARMCGCPMDKLKNAHNYACTGTMIFIATYMLYRAPSLIKSTKTALRQIKAVFMVHGLADGVAVLWRKLRILELLTFTWITMFLMVLYVELIDKGRTWSEVGRILLTGVAETTNTPITLAALAVSVSYVCKWIADLTKLITGGTRSHGHVLAHSGYTEAVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQSLFEIIEVVLLNLPSSPTASRARHARCICIALLLVVIPFFTTKTMLALLPIDIYTAIIIANSATVTARAIGVILKYIVLIVETKSEEPWEGIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIVNIYKRLEHTVSFIKNRNAAVKNINRLSKADVVQLREREDVCAICFIEMKEEARITPCKHYFHGPCLRKWLAVKMVCPLCYTYMKEDDFDSKSSSSGTLNEVQQNEEGAAVEENPENPEEQPEAPNAERAPGDMFDWDDLFGFRAERETRNRNEQRIHGARDMWPLLVDNDAYESDSDAGSEELVIEEENNN
What is the function of this protein?
E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate (By similarity).  Acting downstream of probable Golgi transport protein eas-1, involved in inhibition of activation of transcription factor sbp-1, thereby playing a role in regulating AMsh glial cell size (PubMed:33370778).
What are the official names of this protein?
RING finger protein 145 homolog.
Protein: RLA0_MOUSE
Sequence: MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLIIQQVFDNGSIYNPEVLDITEQALHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETEYTFPLTEKVKAFLADPSAFAAAAPAAAATTAAPAAAAAPAKAEAKEESEESDEDMGFGLFD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, 60S ribosomal protein L10E.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: ISPF_SALNS
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: AROD_STAAE
Sequence: MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.