PharMolix/UniProtQA huggingface dataset:
Protein: MLC2_DROME
Sequence: MAAYTEDQLAEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDERISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEEFVRMVMSG
What are the official names of this protein?
Myosin-2 essential light chain, Myosin II essential light chain, Non-muscle myosin essential light chain.
Protein: UXAC_GEOTN
Sequence: MQPFIDDRFLLQNKHAEVLYHDYAKSLPIIDYHCHLSAKEIAEDRRFHDMTELWLEGDHYKWRAMRALGVEEKYITGSASPEEKFQAWAKTVPYCIGNPLYHWTHLELKRYFQVGVLLNEQTWKEVWDHCNELLQQEGYSARSFMIQSNVEWIGTTDDPLDDLMDHQKIAQDSSFSIKVVPSFRPDAVIEINRPSFLDYVSKLGEVADLSVDDYGQLLQALENRVRYFHEAGCRMADHGLESMPYAECTLDEARVIFQKRKEGFALSREEEEKYQTFTLCFLARLYYSLGWVMQLHIGSIRNTNQKMFQQLGPNTGYDSINDFFFAQPLNAFLNRLERDGQLPKTIVYTLNPAYNYIVASTIGNFPSEGVKGKVQFGAAWWFNDHQDGIIRHLNDLANVGVFSTFVGMLTDSRSFLSYVRHEYFRRIVCNLIGSWIEKGEAPQDYAFLGKIVQDICYFNAKQYFDLS
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: IOD1_CHICK
Sequence: LSIRVLLHKLLILLQVTLSVVVGKTMMILFPDTTKRYILKLGEKSRMNQNPKFSYENWGPTFFSFQYLLFVLKVKWRRLEDEAHEGRPAPNTPVVALNGEMQHLFSFMRDNRPLILNFGSCTUPSFMLKFDEFNKLVKDFSSIADFLIIYIEEAHAVDGWAFRNNVVIKNHRSLEDRKTAAQFLQQKNPLCPVVLDTMENLSSSKYAALPERLYILQAGNVIYKGGVGPWNYHPQEIRAVLEKLK
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).
What are the official names of this protein?
Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CXCR2_GORGO
Sequence: FNMESDSFEDFWKGEDLSNYSYSSALPPFLLDASPCEPESLEINKYFVVIIYALVFLLSLLGNSLVILVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTIYPSNVSPVCYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHINQALDATEILGILHSCLNPLIYAFIGQKFCHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHT
What is the function of this protein?
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.  Binds to IL-8 with high affinity.  Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
What are the official names of this protein?
C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, High affinity interleukin-8 receptor B, IL-8R B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AIM32_PICGU
Sequence: MLCIRRSLSRFVDSCPRPRYDTGCTYCEIPKFPADKQIDFDRNLNGTQPETWKHLLILSHGYPSMEAMPPRIELTPATLSSEINAVKRQMLSPMHPVAVSNVVVNNHTLPNKPLGPQEHFVYLYPDRKSIRFEAKDLATFIARYLVPEEKPEVYNPFKQEVEKTQRIQQSSIEFEEQDITDELVLICGHGSRDVRCGVMGPLLQREFDQVLTQENMSSHVKTGQITHVGGHAYAGNVVYFPRKGESVWYGRVFPEDVQGIVDTTIKQGVIIRDKYRGYVNGA
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: RHAA_ESCF3
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTTELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKAILSQRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG155_CWPXB
Sequence: MNSLSIFFIVVATAAVCLLFIQGYSIYENYGNIKEFNATHAAFEYSKSIGGTPALDRRVQDVNDTISDVKQKWRCVTYPGNGFVSASVFGFQAEVGPNNTRSIRKFNTMQQCIDFTFSDVINIDIYNPCVAPNINNAECQFLKSVL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein OPG155, Protein CPXV163.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG155 protein family.
Protein: GATA_DECAR
Sequence: MINASLKELSLALAAKKVSSVELSSLFLDRIERLNPTLNAFVTVDREKSLQMARDADARIAAGTAGPLTGIPIAQKDIFCAEGWLSTCGSKMLANFVSPYDATVIRKMHAEAGLVSLGKTNMDEFAMGSSNETSFFGSVRNPWDTQRVPGGSSGGSAAAVAARLAPAATGTDTGGSIRQPAALCNLTGLKPTYGVVSRYGMIAFASSLDQGGPMAASAEDCALLLNTMVGFDERDSTSLERPVEDYARDLDKPLDGLRIGLPKEFFGEGCDAEVMAAVRAAIAEYEKLGATCVEISLPNSHLSVPAYYVIAPAEASSNLSRFDGVRYGYRAPEYGNLDDMYMKTRAQGFGAEVKRRILIGAYVLSHGYYDAYYLQAQRIRRLIANDFVEAFKHCDVIMSPTSPSTAFKLGEKAADPVQMYLSDIYTIAVNLAGLPGMSIPCGFVGGLPVGLQLIGNYFAENRLLNVAHRYQQATDWHQRRPGGIE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LEU3_TRIV2
Sequence: MTQNYRITLLPGDGIGPEIMAVAVDVLKVVGQQFDIQFDFQEALIGGAAIDATGEPLPSATLDTCRQSDAVLLAAIGGYKWDSLPPHQRPEGGLLGLRAGLELFANLRPAQILPQLIDASTLKREVVEGVDIMVVRELTGGIYFGKPRGIFTTETGEKRGVNTMVYTESEIDRIGRIAFETARKRRGKLCSVDKANVLDVSQLWRDRITKLSQEYPDVELSHLYVDNAAMQLVRAPKQFDTIVTGNLFGDILSDAAAMLTGSIGMLPSASLGASGPGVFEPVHGSAPDIAGLDKANPLAQVLSAAMMLRYALNQPQAADKIEQAVLQVLEQGDRTGDIMSVGMNLLGCRAMGDSLIKALEKS
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_CANLF
Sequence: MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVHIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RUVC_STRM5
Sequence: MTRILGIDPGSQRTGVGIIDVDATGRVSHVHHQPLVLLGADDFPQRMKLLVLGLADLCREYEPQEVAIERVFMARNPDSALKLGQARGAAISAVVLRDLPVHEYAASEIKLAVVGRGGAEKQQVQHMVGLMLNLKTKLQADAADALAVAITHAHVRATANRLGLSARQAWGRK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PDXS_GEOKA
Sequence: MALTGTDRVKRGMAEMQKGGVIMDVVNAEQAKIAEAAGAVAVMALERVPADIRAAGGVARMADPTVIEEVMNAVSIPVMAKVRIGHYVEARVLEALGVDYIDESEVLTPADEEFHIDKRQFTVPFVCGCRDLGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRKVNAQIRKVVNMSEDELVAEAKQLGAPVEVLREIKRLGRLPVVNFAAGGVATPADAALMMHLGADGVFVGSGIFKSENPEKYARAIVEATTHYEDYELIAHLSKGLGGAMRGIDIATLLPEHRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: RSMC_ECOL5
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTATSRAHTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDANKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLATNGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_DRANE
Sequence: MGQKINPLGFRLGTTQSHHSLWFAQPKKYSEGLEEDKKIRDCIKNYVQNNIRISSGMEGIARIEIQKRIDLIQIIIYMGFPKLLIEDKPRRIEELQINVQKELNCVNRKLNIAITRISNPYGHPNILAEFIAGQLKNRVSFRKAMKKAIELTEQANTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIDAKIDYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMA_STUS1
Sequence: MSVATLSAPEKTRVIVGMSGGVDSSVSALLLLEQGYQVEGLFMKNWEEDDGTEYCTAKEDLADAQAVCDRIGIKLHTANFAAEYWDNVFEHFLAEYKAGRTPNPDILCNREIKFKAFLDYALMLGADLIATGHYVRRRDRDGRSELLKGLDPNKDQSYFLHAVGGEQLAKTLFPVGELEKPEVRAIAEKHSLATAKKKDSTGICFIGERRFSDFLKQYLPAQPGNIEAVDGEVIGRHHGLMYHTIGQRQGLGIGGLKDASDEPWYVLSKDLQRNVLIVGQGNDHPWLFSRALLASEIYWVNPVDLSAPLKLTAKVRYRQSDQACTLEQTSDGYRAVFEVPQRAVTPGQSVVFYDGEVCLGGGVIEQAEPWFEGRA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
Protein: RS14_SALNS
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS153_ARATH
Sequence: MADPEVAAAGIVKKRTFKKFSFRGVDLDALLDMSTDDLVKLFPSRIRRRFSRGLTRKPMALIKKLRKAKIEAPAGEKPAAVRTHLRNMIIVPEMIGSVIGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGVGATNSSRFIPLK
What are the official names of this protein?
40S ribosomal protein S15-3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_CHLCV
Sequence: MNTPSDETRKPPQGKRFAERLPKWLRQVLPTGPVFAQTDTTIKRTGMATVCEEALCPNRACCWSRKTATYLALGDACTRRCGFCNIDFTKKPISPDPEEPQKIAESAKILQLKHIVLTMVARDDLEDGGASFLVRIIDTLHQELPESTVEVLASDFQGNIDALHTLLDSGLTIYNHNVETVERLTPVVRHKATYRRSLFMLEQAAMYLPDLKIKSGIMVGLGEQESEVKQTLKDLADHGVKIVTIGQYLRPSRSHIPVKSYVTPETFDYYRTIGTSLGLFVYAGPFVRSSFNADIVLHNLENKQSDVAKMQN
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_PSEPW
Sequence: MAQLCVALVAGEASGDILGSGLMRALKARHPQVRFIGVGGPLMEAEGMQSYFPMERLAVMGLVEVLGRLRELLKRRKALIQTLIAEKPDVFIGIDAPDFTLNIELKLRQAGIKTVHYVSPSVWAWRQKRVLKIREGCDLMLTLLPFEARFYEEQGVPVRFVGHPLADTIPLAADRQAARMALGLDAGPVVALMPGSRGGEVGRLGALFLDAAQRLVELIPGVHFVLPCANGARRAQLEQMLEGRELPLTLLDGQSHQALAACDAVLIASGTATLEAMLYKRPMVVAYRLAPLTYWILKRLVKSPYVSLPNLLAQRELVPELLQDAATSEALAQTLAPLVADGRQQTERFDEIHRTLRRDASNQAADAVLALLKDR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RS16_HELAH
Sequence: MTVIRLTRIGRKKKPFYRVVVTDSRKRRDGGWIESIGYYNPLSEPKDIKIDKERLDYWKGVGAKMSERVEKLSQKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PDXB_ACIBS
Sequence: MKIVADENLAFTDYFFSEFGDIQHKAGRTLTHTDVQDAEALLVRSVTAVNESLIQNTALKYVGSATIGTDHLDIQALEKQGITWANAAGCNAQAVAEYVITALLHLDASLLEQQEKFTLGIVGLGNVGKRLAYMAQLLGWKVIGFDPFVQLDSIENVSFQTLLQQANAVSIHVPLTKKGEHATYHLFDEKAFAALQPNTILINSARGPVVKEAALIEDIQCTQRKVVLDVFEHEPVISEGLLNMLALATPHIAGYSLEGKARGTQMIYEAFCQKFGYDINKRFETQLPACEDYFSGHDLKAVLKQKLSQIYDIAQYDANIRACVKEGKVEQKAFDLLRKNYPLRREWAAHGGPQA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_LACDB
Sequence: MDQAKQDELKKAAAKKAAALVEDGMVLGVGTGSTVKFFIDELGKKKAAGLTLKAVVTTSSRSQKQLEGYGFTVSPLSEVDQVDLTVDGADRVDKQLNGIKGGGAALTLEKNVAVNSKKNVWIVDESKVVDHLSGFALPVEVLPISCMQVEKRLADEGLKPEFRLTEDGQRLKTHYGNYILDLKLDRIPVPSGLADYLDHTVGVVEHGLFLNICDQVIIARDNGEIEVRSR
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: HPS_STAAM
Sequence: MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAVKHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGGIKPDTIKDIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: Y088_OSHVF
Sequence: MIIMKSIILLLAWFLTKTQANMLTESLYLSEYEGSVVLNIIDKNLNGISTLSIFNDSTKLQEVRYVASVCSLRSGSFNITCNVITYGTYHVRMFLSGLNMSAFDLYRLRYVYVGLRDAINYNPKYAEAVMAPFALIGNNNIVTIKLIKDGDNITVGCGFGNVDLSTVNTHASKIGRNINPRFMVGVYTNDSNKLIEDDIYSRYTDSESAGVMRKCNLNEVKTTPQEDCIQPFCTKGTVYGNNLVYGSRLRCFSRTRCSQRSRTVPQSVPWYIPSGFTGKQFMYLDNRLGYLLGLDLTTAIFKYTPIVVGHIVSEYLTGIMNYKRLSVRKGPNIDMRGIIGGEIKMILIRNYRKMLDMSGFTPLPVNGCYVTVIKFIGDKRVFNRVWTPSNNTDDGEEHVFVFHQKRSSNIRDYTLRIFPDSGMDTEGSKYTMNTITDVGCSRETHHKSVYPATIKKAIERFCVDQPNISCEYVKDIDRVDINPCGCKQRANRCGERYSNNTLKATIEFEVPKIYDTPYTCEFLGYKSVNSLTFDSPPPPPTTTQAPPPPPTTTQAPPPPPTTTQAPPPPIVINTTAAPLAPITNATLPPSDVITPEAVNLTDDTPVVNEPVNSTFINDTDVLDDSPTTSAPQAPGIVGIIVNKITTTPAPSIGRAPIPPPDVPVEPPRSIPTTNAPSPEEDTVVLSKSDIMRRFLIRLKTRDGETVDIYTWPELNLAPFKTLSYAGIGVVSFALLFTILVVCLIKFSI
What are the official names of this protein?
Putative transmembrane protein ORF88.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: GLGA_EXIS2
Sequence: MKVWFAATEATPFIKTGGLADVVGSLPLALAEEGAEVSVILPNYGQIKEQYKLEMEFLFDFIVPVGWRQQFGAVLRLKQDGVTFYFIDNEYYFKRDGVIYGHYDDAERFAYFSRAVLEMIQRVDAEEVPDVIHCHDWQTGVLPAFLRIHYQHLNRYQEIKTVFTIHNLQYQGVFPEEVLGDLLGLSHEHFTAEGIAHNGLVNYMKAGLVHANQITTVSPSYRDEIMDPYYGETLEPVLQHRAVDVRGILNGIDYRQFSPETDEHLVENYDVKTVEEGKAANKAALQQELGLPVNPDVPLFGFVSRLVDQKGIDLLAHILPDLFELDAQFIILGSGEAEYEGLFQHASTIRPDKVASYIGFDVGLAQRIYAGSDAFLMPSRFEPCGLSQLISMKYGSLPIVRETGGLRDTVQPFNQFTLEGNGFSFSNYNAQEFLDAIKRTIETYHDKPVFKHLIETAMQEDFSWIRSADEYLALYRLIAPSAD
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: NPM_BOVIN
Sequence: MEDSMDMDMSPLRPQNYLFGCELKADRDYHFKVDNDENEHQLSLRTVSLGAGAKDELHVVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEEEEEEEVKLLSISGKRSAPGSGSKVPQKKVKLAADEDEDDDDDDDDDDDEDDDDDDFDEEVEEKAPVKKSVRDTPAKNAQKSNQNGKDSKPSTPRSKGQESFKKQEKTPKTPRGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
What is the function of this protein?
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF.  Binds ribosome presumably to drive ribosome nuclear export.  Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids.  Acts as a chaperonin for the core histones H3, H2B and H4.  Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA.  May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules.  In concert with BRCA2, regulates centrosome duplication.  Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication.  Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.  Antagonizes the inhibitory effect of ATF5 on cell proliferation and relieves ATF5-induced G2/M blockade.  In complex with MYC enhances the transcription of MYC target genes (By similarity).  May act as chaperonin or cotransporter in the nucleolar localization of transcription termination factor TTF1 (By similarity).
What are the official names of this protein?
Nucleophosmin, NPM.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Can shuttle between cytoplasm and nucleus. Co-localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. NEK2 is required for its localization to the centrosome during mitosis.
Protein: FACR4_ARATH
Sequence: MDSNCIQFLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEKDLFRVLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERYDVGLSVNTFGPLNVLNFAKKCVKGQLLLHVSTAYVRGEKSGLLHEKTFHMGETLNGHRKLVIETEMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGNYRENLPIVIIRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVANAMVTAAAIHAGKLGSQTVYHVGSSCKNPITFEQIHDLAASYFTKNPLVRRDGSSILVSKGTILSTMAQFSFYMTLRYKLPLQMLRLIYVIYPWWNGNKYKDIDRKIKLAMRLVDLYRPYVLFKGIFDDTNTEKLRLKRKEINKEMYGLFEFDPKSIDWEDYMTTIHIPGLITYVLKK
What is the function of this protein?
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols (PubMed:20571114).  Catalyzes specifically the formation of C18:0 and C20:0 fatty alcohols.  Provides the fatty alcohols required for synthesis of suberin in roots, seed coat and wound-induced leaf tissue (PubMed:20571114).  Provides the fatty alcohols required for synthesis of alkyl hydroxycinnamates in root waxes (PubMed:22797656).
What are the official names of this protein?
Probable fatty acyl-CoA reductase 4.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
Protein: TRHO_DELAS
Sequence: MSDILNISCYKFTPLPDAAALRDTLAERAQALALKGTILLAEEGINFFLAGPAQAVHSFVDQLRADDRFADLAPKESWSDTVPFRKMLVKVKREIIRMDHPTIRPAEGRAPSVSPATLRRWLEQGHDDEGREVVTLDTRNDFEVDAGAFKDTIDWRITKFTEFPPALRAHKAELADKTVVSYCTGGIRCEKAAILMRDEGLEHVYQLEGGILKYFEETDGAFYDGGCFVFDERRAVGADLAITPLAPAEPLEPIQPTSPPGKA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LIAS_DROGR
Sequence: MLRRLNSPTAILVRTASTRTEKLEEIRDRLSKGPNFQDFIQNSDNSKDDFENYDGKLRREKGETQQLRLPPWLKTTIPMGKNYAKIKSQLRDLKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARAPPPLDVNEPVNTAKAISSWGLDYIVLTSVDRDDLPDGGSKHIAETVREIKARNSNIFVECLVPDFRGNLECVQTIAGCGLDVYAHNIETVEKLTPFVRDRRAHYRQTLKVLNEAKQFNPNLITKSSLMLGLGETDAEVEQTMLDLREAGVECLTLGQYMQPTKRHLKVIEYVTPEKFKHWEQRGNELGFLYTASGPLVRSSYKAGEFFITSILANRRKSV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.