PharMolix/UniProtQA huggingface dataset:
Protein: CYB_MOGIM
Sequence: MTNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDTDKIPFHPYYTIKDILGALVLILALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILALMPFLHTSKQRSMMFRPISQCLFWLLVADLLILTWIGGQPVEHPFIIIGQLASILYFSLILIMMPLASLVENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BGLL_EMENI
Sequence: MRSLIRSGALNAFLAASLATGQVLTWDEAYTKATSDLSLLSQEEKVGIVTGVTWQGGPCVGNTYEPTSIPYPSLCLQDGPLSVRFANPVTVFPAGINAGATWDRELIRARGVAMGAESRGLGVHVQLGPVAGALGKIPSAGRNWEGFSNDPYLAGIAMAEAIQGMQSSGVQACAKHYLLNEQEYNRDTISSNADDRTIHELYLWPFYDAVKANVASVMCSYNKINGTWACEHDALLNGLLKGELGFKGHVLSDWNAQHSTVQSANTGLDMTMPGSDFSTPPGSIYWGDNLAAAIADGSVPQERLDDMVTRILAAWYLVGQDQGHPPVAFSSWDGGAASVNVTTPEHGELARTIARDSIVLLKNTNGSLPLAKPASLAVIGSDAIVNPDGANACADRGCNKGTLAQGWGSGTAEFPYLVAPLDAIEEKLAGAGTAIITSTTDDATSGAEAAAAAETAIVFITSDSGEGYITVEGHEGDRNNLDPWHNGNLLVQAVARTNTPTIVVLHSVGPVTLETILAEPNVVAVVWAGLPGQESGHALTDVLFGDYAPSGKLPFTIGKSEEDYGADWTTSQVDDFAEGLFIDYRHFDQYGIEPRYEFGFGLSYTSFNYSTLSTSISTTPGPTTGETIVGGPSDLFAPIGTVSAYVANTGHVAGAEVVQLYIGYPDSAPSIPPKQLRGFDKLHLVPGESGIATFELTRRDISYWDVGLQKWVVASGTFEVFVGASSRDIRLTGSFTV
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase L, Beta-D-glucoside glucohydrolase L, Cellobiase L, Gentiobiase L.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_CAMJJ
Sequence: MSKADIIVGIQWGDEGKGKVVDKLCENYDFVCRSAGGHNAGHTIWVNGVRYALHLMPSGVLHPRCINIIGNGVVVSPEVLIAEMAQFENLKGRLYISDRAHLNLKHHSLIDIAKEKLKGKNAIGTTGKGIGPSYADKINRTGHRVGELLEPQRLCEALIKDFEANKTFFEMLEIEIPSAEELLADLKRFNEILTPYITDTTRMLWKALDEDKRVLLEGAQGSMLDIDHGTYPYVTSSSTISAGALTGLGLNPKEAGNIIGIVKAYATRVGNGAFPTEDKGEDGEKIAQIGKEIGVSTGRKRRCGWFDAVAVRYTARLNGLDALSLMKLDVLDGFEKIKICRAYEYKGMEIDYIPSDLENVQPIYEEMDGWDKVFGIKDYDLLPENAKKYIARLEELAGVKVKYISTSPERDDTIIL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_PHOLL
Sequence: MNDSEFHQLADQLILYIEGQLDNYDGNADIDCETNGGVMTLSFDNDSKIIINRQEPFHQIWLATKGGGYHFDYKEGQWICDRSGDNFLTMLAYAITEQSGEQFSFP
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: THIC_BRADU
Sequence: MNIRSNPQQTVPAVTTGPLSSSRKIFASPDAAPDLRVPLREIILSEGAGEPNLPVYDTSGPYTDPSVTIDVNAGLARSRKQWVLERGGVEEYEGRQVKPEDNGNLSTDKAARAFSAYHKPLRGLDGHKITQLEFARAGIITKEMIYVAARENLGRKEQLERAEAALADGESFGAEVPAFITPEFVRSEIARGRAIIPCNINHSELEPMIIGRNFLTKINANIGNSAVTSSVEEEVEKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPVPIGTVPIYQALEKCNGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLSYIHLTANRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHASDLAKGHPAAQLRDDALSRARFDFRWSDQFNLGLDPDTAKNFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPNSIGMSLSGTAEDGMKQMSAKFKEMGSSVYLDAEKVKESNRVL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DCA16_BOVIN
Sequence: MGPRNPSPDPLSESESEEEENTNYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDASTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDHATLNGALQFATKQLSRTLSRATPHAFLPKLVPLAFSS
What is the function of this protein?
Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins.
What are the official names of this protein?
DDB1- and CUL4-associated factor 16.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y208_LISWE
Sequence: MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMESRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEVQDY
What are the official names of this protein?
UPF0145 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ARAA_SHEB2
Sequence: MKAFKQKQVWFVTGSQDLYGPKVLEQVAKNSEQIVHGFNQSDAISMEVVYKPTVKSPREIYAVCQAANSDENCVGVILWMHTFSPAKMWIAGLNELSKPFMHLHTQFNAELPWADINMNYMNTHQSAHGCREFGYIGTRMRKERKVVVGHWQTNDVQAQVDDWCRAAAGWNESQNLRIARFGDNMRQVAVTEGDKVAAQIQFGYEVHAYSLGELNDAINAVADNDITAQIDRYASEYVISNELFNDEYQLDRLRKEAQIELGLTQFLKDGEFGAFTNCFENLTGMTGLPGLATQRLMANGIGYGGEGDWKTAAMVRIMKVMGQGRTGGTSFMEDYTYNFGVTDQVLGAHMLEVCPSIAAAKPRLEVHRHTIGVRCDVPRLLFTGKAGPAINVSTIDLGNRFRIILNELDTVTPPQELPNLPVASALWEPRPNLSIAAAAWIHAGGAHHSAYSQAISTDNIVDFAEMAGAELVIIDADTRIRQFKNELRQNSVYYGLARGL
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: YCF4_PIPCE
Sequence: MNRRSERIWIEFIMGSRKTSNFCWACILLLGSLGFLLVGISSYLGRNLISLFPSQQINFFPQGIVMSFYGIAGLFISSYLWSTILWNIGSGYDRFDRKEGIVCIFRWGFPGINRRIFLRVFMGDIQSIRIEVKGGVYPRRVLYMDIRGQGSVPLTRTDENFTPREIEQKAAESAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NADD_CLOK1
Sequence: MVKKAIFGGTFDPIHNGHIHIAYEAIYRLGLDEIVFMPTGNPPHKAKKSITDAFLRYEMVKVAIRSESKFTVSNYEVNKTTLSYTYSTLEHFNKLESKTEWYFLTGADCLMDIEKWSRVDSIFRLCKFIVFNRPGFPAFTSESIEDQKKKIEDKYSTNIIYLDAPLFDISSTVIRNSVKEGKNVNYFLPESVCNIIKQLNLYK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ARGE_ECO8A
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_PROM9
Sequence: MTQLSSNDVPSMGRRQFMNLLTFGTATGVALGALYPVANYFMPLRAGGGGGGTSAKDELGNPVTKTGWLATHQAGDRSLVQGLKGDPTYLIVNEGGEIGEFGLNAICTHLGCVVPWDSGANKFICPCHGSQYDTNGKVVRGPAPLSLALAHVDIEDDAVLVKQWSETDFRTNENPWWA
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: EXBD_HAEDU
Sequence: MKKFDEINIIPFIDIMLVLLAIVLVTASFISQGKIQVNVPKATTTQAMKADELAKLLTITENNGFYFNDKLITKEDLSTEIASWDKTQKVTLKVDSAVAFEKFVELTDLLSANEIKNVAIVTKKDTSKK
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
What are the official names of this protein?
Biopolymer transport protein ExbD.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CCME_TERTT
Sequence: MHPKRKQRLILVLFVVLVSSVGVSLTLYALNENINLFYPPTKIVNGEAPSGRTIRAGGCVVPGTVTRAKDNLEIDFDVTDGVSELSVTYDGILPDLFAEGEAVVLTGMLDHDGVFVATKVLAKHDENYMPPEVADTVTTDGVEHMKTCKGISYDS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RNPA_CAMJ8
Sequence: MKNFDKFSTNEEFSSVYKVGKKWHCEGVIIFYLNSYEKKIAVVASKKVGKAVVRNRSKRILRALFAKFERYLQDGKYIFVAKNEITELSFSRLEKNLKWGLKKLECFK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PG079_VACCW
Sequence: MSKVIKKRVETSPRPTASSDSLQTCAGVIEYAKSISKSNAKCIEYVTLNASQYANCSSISIKLTDSLSSQMTSTFIMLEGETKLYKNKSKQDRSDGYFLKIKVTAASPMLYQLLEAVYGNIKHKERIPNSLHSLSVETITEKTFKDESIFINKLNGAMVEYVSTGESSILRSIEGELESLSKRERQLAKAIITPVVFYRSGTETKITFALKKLIIDREVVANVIGLSGDSERVSMTENVEEDLARNLGLVDIDDEYDEDSDKEKPIFNV
What is the function of this protein?
Plays an essential role in viral DNA replication.  Binds to ssDNA with high affinity and localizes to cytoplasmic factories where nascent viral genomes accumulate.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.
What are the official names of this protein?
Protein OPG079, Protein I3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG079 family.
Protein: EFR3_CANGA
Sequence: MQLGHIFTPKHQKLVNQCYPSGRAPDKKPKSSETSYLIYYVNSRSSKLEKVSNYLIKRTNTDLSRRRVGNVCVTLELMAKIVDHCKENLNVFVKEFLTLMNMVLTNNSINNDVTVIELLEITFGTICRNLDGAYYGGDTEFIKMFKSFVDLLFEVVSKRLNNDDLMLKVCIDISTIIGIASDPQLNYLVPKCVETAIDQLQARYPQFKENSLLEQPSLTKRLSKTQTRAQEVLEIPTADNDLCVATLHNYFNTTETDKLNLSIRSLIKKLQSTPNKELLEFISNDIPVQLRYIVVLLLTRQVSNYERNQVSGSQGNPDGALNSLKLISCLLVSKISIVGLSVLDIMRKVLAVQLKSKESMPLVHQCRVTIKDLNNKIYYSEQTSDMLYDLVVKIKNVQNEVEKRILVDDMKYIVDDISQPVINVDLLTELVPFMKGSVIQLLNITEEHISGGSTLSRLFQMVRDIEDRNLQSKAMSIIFDKYKKIILLPGLNYFQMNIKEPEYTYYLYHFNAAKTLGVTSYYSETQQKLDNGELFTKEELMKYYKNANNTQFGEKGMQILMSYDNQISNSDLLNDRPLSPVFSSKPLSSPMGLISPQAQTNTQLNQPMRFVSDDVHSWKVSRPSIPKVSDLKKAMKNGSSTKNKPLRGSQSVKSRVTNITFLLSELRSTTAGDDSHIIDPDEEEVVGIDKMEIARSLSGRGRNSVVVEDVSTNRASFVPATVNEDDEFRDAVEDVEAYSTSRGKIFANY
What are the official names of this protein?
Protein EFR3.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
Protein: RNH2_PECCP
Sequence: MSEIFIYPQATCIAGVDEVGRGPLVGAVVTAAVILDPTRPIVGLADSKQLSEKRRLALYDEIKEKALAWSLGRAEPEEIDQLNILHATMLAMQRAVAGLAVVPDFVLIDGNRCPALPMPSQAVVKGDSRVAEISAASIMAKVTRDREMVELDERFPAYGFAQHKGYPTAFHLEKLAALGATEFHRRSFAPVKRALGLA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEP1A_OSTSE
Sequence: SDAVADGDHAISGVVDS
What is the function of this protein?
May act as an antimicrobial peptide.
What are the official names of this protein?
Septenin 1a.
What is the protein family that this protein belongs to?
Belongs to the Frog skin active peptide (FSAP) family. Septenin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_LARHH
Sequence: MLTLTHYLVLAAVMFAISVLGIFLNRKNVIVLLMAIELMLLAVNFNFIAFAHYFGDTAGQIFVFFVLTVAAAESAIGLAILVVLFRNLATINVEDLGQLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_BEUC1
Sequence: MLIPRRTKHRKQHHPRRTGAASGGTTIAFGDYGIQAVEGGYLTNRQIEAARIAMTRHIKRGGKVWINIYPDRPLTKKPAETRMGSGKGSVEWWIANIKPGRVLFELAGVDEPLAREAMRRAQHKLPMKTRFVRREGGDQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HIS1_CORDI
Sequence: MLKIAIPNKGSLSEAAVEILAEAGYAGRGESKTLNVYDKTNDVEFFFLRPKDIAIYVAGGQLDLGITGRDLATDSHANVEEVMSLGFGNSSFRYAAPADQKWTVEMLEGKRIATSYPNLVRDDLQARGINATVIRLDGAVEISIKLGVADAIADVVSTGRTLRKQGLATFGEVICQSEAVIVGQQGNVVDNEQKVFLRRIEGILHAQNYLMLDYNIDRVNLAASEKITPGISGPTVSPLARENWVAVRAMVPRKEANHIMDQLSELGAQAILASEIRIARL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHH_TRIHE
Sequence: YGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTVMNQWPGVKLRVTEGWDEDGHHLEESLHYKGRAVDITTSDRDKSKYGTLSRLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes.  Displays floor plate-inducing activity.  Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes.  In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Sonic hedgehog protein C-product: Secreted, extracellular space. Sonic hedgehog protein N-product: Cell membrane; Lipid-anchor. The C-terminal peptide diffuses from the cell, while the N-product either remains associated with lipid rafts at the cell surface, or forms freely diffusible active multimers with its hydrophobic lipid-modified N- and C-termini buried inside.
Protein: NIFH_RHOP2
Sequence: MAALRQIAFYGKGGIGKSTTSQNTLAALVELGQKILIVGCDPKADSTRLILNTKMQDTVLSLAAEAGSVEDLELEDVMKIGYKGIKCTEAGGPEPGVGCAGRGVITAINFLEENGAYEDVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYASSGGVRLGGLICNERQTDRELDLAEALAARLNSKLIHFVPRANIVQHAELRRQTVIEYAPDSQQAQEYRQLANKIHANSGNGTIPTPITMEELEGMLLDFGIMKTDEQALAELAEKEAAKAAAATA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: DCD_EHRCJ
Sequence: MSVMPDHWIKDKAIQEKMIDPFIDYKESSGILSYGLSSYGYDARIDNKFKIFTNINPVTVDPKNFPLGSFIDKEEDICIIPPNSFVLAKTVEYFKIPKDILVMCVGKSTYARCGIVVNVTPLEPGWEGYVTLEFSNTTPLPAKIYAFEGACQFIFLKGDSQCSLSYNEMKGKYMKQLDVTLPIVNNS
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TSAB_BACSU
Sequence: MTILAIDTSNYTLGIALLREDTVIAEYITYLKKNHSVRAMPAVHSLLNDCDMAPQDLSKIVVAKGPGSYTGVRIGVTLAKTLAWSLDIPISAVSSLETLAANGRHFDGLISPIFDARRGQVYTGLYQYKNGLLEQVVPDQNVMLADWLEMLKEKDRPVLFLGHDTSLHKQMIEDVLGTKGFIGTAAQHNPRPSELAFLGKEKEAADVHGLVPDYLRLAEAEAKWIESQK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_STAAN
Sequence: MFHHISVMLNETIDYLNVKENGVYIDCTLGGAGHALYLLNQLNDDGRLIAIDQDQTAIDNAKEVLKDHLHKVTFVHSNFRELTQILKDLNIEKVDGIYYDLGVSSPQLDIPERGFSYHHDATLDMRMDQTQELTAYEIVNNWSYEALVKIFYRYGEEKFSKQIARRIEAHREQQPITTTLELVDIIKEGIPAKARRKGGHPAKRVFQALRIAVNDELSAFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVFQEYEKGPEVPRGLPVIPEAYTPKLKRVNRKPITATEEDLDDNNRARSAKLRVAEILK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_BURMA
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SPX_STRPQ
Sequence: MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRKQELRQATIKAEIEG
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_LEIXX
Sequence: MATFVDRVTVHLRAGNGGNGCVSVRREKFKPLAGPDGGNGGNGGDIVLVADPQVTTLLGYHRRPHRSSGNGGFGMGDHRSGHTGEDLELPVPVGTVVKSSEGAELADLTEPGMRIVAAPGGIGGLGNAALSNPKRKAPGFALLGTPGWEGDILLELKTVADIALVGYPSAGKSSLIAALSAAKPKIADYPFTTLHPNLGVVQVGDVRYTVADVPGLIEGASEGRGLGFEFLRHVERCSALLHVLDCATLEPGRDPLSDLDVILAELAAYPVPEGQLPLLERPQLIALNKIDVPDARELADFLRPDLEARGYRVFEISTVSHEGLRPLSFALAELVERARKEQAVLDETRPRIIVRPKTVDDSGFVVKVEGGSEGPVYRVLGAKPERWVAQTDFQNDEAIGYLAARLAKLGVEDQLVRVGAVAGSTVVIGRENGVVFDWEPTLTSAAELISSPRGTDARIGVNARPTRAQRREDYFDRMDAKAEARAELLREREAGLWKDDDAAVQGGSEETGRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.