PharMolix/UniProtQA huggingface dataset:
Protein: CFA20_MOUSE
Sequence: MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (By similarity).  Involved in the regulation of the size and morphology of cilia.  Required for axonemal microtubules polyglutamylation (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 20, Gene trap locus 3 protein.
What is the protein family that this protein belongs to?
Belongs to the CFAP20 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: Y2548_CLOP1
Sequence: MKIIIDGDGCAGRDIIEEVGKKHSVKILIYCTINHMINSDYSEVRMVDGGFQSVDMYVANNTEENDIVITQDYGVAAMALGKGALAISPRGYIYDNDNIDRLLFERHLSQKNRRAGGKSKGNHKRNKEDDDRLYYNLEVLIEKVKAILN
What are the official names of this protein?
UPF0178 protein CPF_2548.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: YJ55_YEAST
Sequence: MEHPAYTLSLLTTAGGLMGYYRKGSIPSLVSGLVFGSVYGIAGYLLHMNRDGGLEMALGASTLLLGAGVIRGMPSRFTKPVPVVLTALGGLGSYYYYNKYKEFYP
What are the official names of this protein?
TMEM14 protein homolog YJR085C.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: DAD1_PIG
Sequence: MSASVLSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RFBA1_KLEPN
Sequence: MSIKMKYNLGYLFDLLVVITNKDLKVRYKSSMLGYLWSVANPLLFAMIYYFIFKLVMRVQIPNYTVFLITGLFPWQWFASSATNSLFSFIANAQIIKKTVFPRSVIPLSNVMMEGLHFLCTIPVIVVFLFVYGMTPSLSWVWGIPLIAIGQVIFTFGVSIIFSTLNLFFRDLERFVSLGIMLMFYCTPILYASDMIPEKFSWIITYNPLASMILSWRDLFMNGTLNYEYISILYFTGIILTVVGLSIFNKLKYRFAEIL
What is the function of this protein?
May form an ATP-driven O-antigen export apparatus, in association with RfbB.
What are the official names of this protein?
O-antigen export system permease protein RfbA.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_STAA1
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: L2HDH_INDAL
Sequence: MDFQVIIIGGGIVGLATGLKIKQRNPNIKVALLEKEEEVAKHQTGNNSGVIHSGLYYKPGSLKAKNCIEGYHELVRFCEEENIPFELTGKVVVATRKEQVPLLNSLLERGLQNGLKGTRSITLDELKHFEPYCAGVAAIHVPQTGIVDYKLVAEKYAEKFQILGGQVFLGHKVIKVETQNTASIIHTSKGSFSTNLLINCAGLYSDKVAQMNQKESLDVKIIPFRGEYYKIKKEREYLVKNLIYPVPDPNFPFLGVHFTRMMKGGVEAGPNAVLAFKREGYKKSQVNFSELAETLSWPGFQKVASKYWKTGMGELFRSFSKKAFTDALKELIPDIQESDLIEGGAGVRAQACDRTGGLLDDFCIREDQNAIHVLNAPSPAATSSLSIGGTVCEWALKRF
What is the function of this protein?
Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG or(S)-2-hydroxyglutarate) to 2-oxoglutarate (alpha-ketoglutarate).  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCPIP).  Also displays a very low oxidase activity in vitro on L-2-hydroxyglutarate with O2 as the electron acceptor, but this activity is most likely not physiological.
What are the official names of this protein?
L-2-hydroxyglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L2HGDH family.
Protein: ATPA_BARQU
Sequence: MDIRPSEISKILKEQIRDFDQKAEVSEIGWVLSVGDGIARVYGLDNIQAGEMVSFSNGVHGMALNLEIDNVGVVIFGSDRDIREGDSVKRLGAIVDVPVGPALLGRVVDALGNPIDGKGPLKATERRRVDVKAPGIIPRQSVHEPMPTGLKAIDALIPIGRGQRELVIGDRQTGKTAILLDTFLNQKPFHEKGAGNEQDKVYCIYVAIGQKRSTVAQFVKVLEERGALEYSIIVAATASDPAPMQFIAPLAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNAENGSGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKTEEQVVVIFAGVNGYLDALAVSDVGRFEQGLLTLLRSDHPDLLQAIAHQKQITDDVKDKLIVVLNTYAKIFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ERF2_NICSY
Sequence: MYQPISTEFPVYHRTSSFSSLMPCLTDTWGDLPLKVDDSEDMVIYGLLSDALTTGWTPFNLTSTEIKAEPREEIEPATSPVPSVAPPAETTTAQAVVPKGRHYRGVRQRPWGKFAAEIRDPAKNGARVWLGTYETAEEAALAYDKAAYRMRGSKALLNFPHRIGLNEPEPVRLTVKRRSPEPASSSISPASENSLPKRRRKAVAAKQAELEVQSRSNVMQVGCQMEQFPVGEQLLVS
What is the function of this protein?
Transcription factor that binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.  Probably acts as a transcriptional activator (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor 2, NsERF2, Ethylene-responsive element-binding factor 2, EREBP-2.
What is the protein family that this protein belongs to?
Belongs to the ethylene-response factor family. Class 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HTPX_YERPG
Sequence: MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGAFVSLLMSKWMALRSVGGEVIERPRNETEYWLLETVRRQSQQVGIAMPQVAIYQAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHVANGDMVTMTLIQGVVNTFVIFISRLIAQIAAGFLSGDRDGESNSPGNPMVYFAVSMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEAGSMMAFCINGKSKTFSELFMSHPPLDKRIEALRSGQYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU2C1_JASNU
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDLPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSFCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHAFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALLFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNIIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFRCGWQAGLYSLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SECA_RHOCA
Sequence: MLGLGYIGRKLFGTPNDRKVKRTRPLVAKINALEPAFEKLSDAEIVAKTRELQARAQAGESLDALLVEAFANCREAARRALGLRAFDTQLMGGIFLHQGNIAEMKTGEGKTLVATFPAYLNALAGKGVHIVTVNDYLARRDSEWMGKVYRHLGLTCGVVYPFQPDDEKRAAYGADITYATNNELGFDYLRDNMKSSVAEMYQRDHFFAIVDEVDSILIDEARTPLIISGPSQDRSDMYRTLDAYIPFLTEEHYKLDEKQRNATFTEEGNEFLEQKLQADGLLPEGQSLYDPESTTIVHHIGQALRAHKLFFKDQNYVVTDDEIVLIDEFTGRMMKGRRLSDGLHQAIEAKERVTIQPENVTLASVTFQNYFRLYEKLAGMTGTAVTEAEEFGDIYKLGVVEVPTNRPVARKDEHDRVYRTAKEKYAAVIEAIKTAHEKGQPTLVGTTSIEKSEMLSEMLKAEGLPHNVLNARQHEQEAQIVADAGRLGAITIATNMAGRGTDIQLGGNVEMKVQEEIAANPEAAPEEIRARIEAEHAAEKQKVIEAGGLFVLATERHESRRIDNQLRGRSGRQGDPGRSLFFLSLEDDLMRIFGSDRLEGVLSKLGMKEGEAIIHPWVNKSLERAQAKVEGRNFDWRKQLLKFDDVMNDQRKAVFGQRREIMETDEISEIVADMRQQVIDDLIDDFAPPKSYVDQWDIEGMRAAFIDHAGVDLPLADWAAEEGVDQDVLRERVTAALDAVMAQKTEAFGAETMRVIEKQILLQTIDAKWREHLVTLEHLRSVVGFRGYAQRDPLSEYKTESFQLFESMLDSLRYEVTKRLGQIRPMSDEERAEMLRQQAAALAAAEGAADPAEAPAPQPAAQVALAAAPGFVESDPTTWGEPSRNDPCPCGSGEKFKHCHGRLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=SecA is found predominantly with the membrane fraction.
Protein: APAH_PSESM
Sequence: MAVYAVGDLQGCLEPLQCLLEHVRFDPVQDRLWLVGDLVNRGPQSLQTLRYLYSIRESLVCVLGNHDLHLLAVARKNELLKKGDTLREILEAPDRDELLRWVRQQKLMHYDAERNIAMVHAGIAPQWSVKKALKQAAEVEHALQDDQLYGAFLDGMYGNEPAKWNNDLQGVTRLRVITNYFTRMRFCTSDGKLDLKSKEGVGTAIPGYAPWFSHQNRKTRDVKIIFGHWAALEGRCDEPGVFALDSGCVWGGAMTLLNVDTLERHQCNCDAVGNAATGIIASAQPGNAHIQQIPAQEPKQ
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: GADE_ECOLI
Sequence: MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVIIDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEITYGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKLRRMSDIVTLGITSYF
What is the function of this protein?
Regulates the expression of several genes involved in acid resistance.  Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions.  Binds directly to the 20 bp GAD box found in the control regions of both loci.
What are the official names of this protein?
Transcriptional regulator GadE.
Protein: Y12B_BPT4
Sequence: MMHIVMIGVNEKLSLVKLKNLGGNPIGVINAVFDTALQTMKQYKIDACLLRVLKSSKCSLQVPRVVL
What are the official names of this protein?
Uncharacterized 7.4 kDa protein in Gp54-alt intergenic region.
Protein: THIG_BACTN
Sequence: MEKLVIAGREFDSRLFLGTGKFNSNEVMEQAILASGTEMVTVAMKRIDMDDKEDDMLKHIIHPNIQLLPNTSGVRDAEEAVFAAQMAREAFGTNWLKLEIHPDPRYLLPDSIETLKATEQLVKLGFIVLPYCQADPVLCKRLEEAGAATVMPLGAPIGTNKGLQTKEFLQIIIEQAGIPVVVDAGIGAPSHAAEAMELGASAVLVNTAIAVAGNPVEMALAFKAATEAGRRAYEAGLGLQADNFIAEASSPLTAFLE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CHLAA
Sequence: MIQPQTRLKVADNTGAKEIMCIRVLGGSRVRYGRVGDIIVASVKVATPGGQVKKGDVVKAVIIRTAKEYGRPDGSHIRFDDNAAVLIGKENNPRGTRIFGPVARELREKQFMRIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GGTA1_HUMAN
Sequence: MNVKGKVILSMLVVSTVIIVFWEFINSTEGSFLWIYHSKNPEVDDSSAQKGWWFLSWFNNGIHNYQQGEEDIDKEKGREETKGRKMTQQSFGYGTGLIQT
What are the official names of this protein?
Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase, Glycoprotein alpha-galactosyltransferase 1 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: CAPP_PSEA7
Sequence: MPEIDARLREDVHQLGELLGDTIREQYGPAFLDKIERIRKGAKAARRGSAEGAQQLTATLDGLEESELLPVARAFNQFLNLANIAEQYHRIRRRRPNEPEPFENLALEELLGRLKDAGHAPGQLARQLAGLEIELVLTAHPTEVARRTLIQKYDAITAQLATKDHADLLPEERSRIQRRLQRLVAEVWHTDEIRKVRPTPVDEAKWGFAVIEHSLWEALPNVLRHVDEVLLRSTGERLPLSAAPLRFASWMGGDRDGNPNVTAGVTREVLLLARWMAADLYLRDIDRLAAELSMQEASPALLARVGDSAEPYRALLKQLRERLRLTRSWTHQALAGEVPAAEGVLEHNRDLVEPLQLCHESLHACGMGVIADGALLDCLRRAATFGLFLVRLDVRQDAGRHAAALSEITEYLELGSYAEWDEKTRLEFLLEELNSRRPLLPAHYQPSAETAEVLATCRAIAAAPPASLGSYVISMAGQPSDVLAVQLLLKESGVDWPMRVVPLFETLDDLDNAGPCMERLLTLPGYRSRLSGVQEVMIGYSDSAKDAGTLTAAWAQYRAQEKLVEICRHHEVELLLFHGRGGTVGRGGGPAHAAILSQPPGSVAGRFRVTEQGEMIRFKFGLPDIAEQNLNLYLAAVLEATLMPPPAPEPAWRAQMDRLAKDALHAYRRVVRDDPQFVEYFRLATPEQELGRLPLGSRPAKRREGGVESLRAIPWIFAWTQTRLMLPAWLGWETALLNAIERGEGALLGQMRERWPFFTTRIDMLEMVLAKADADIARLYDERLVPLELRPLGRRLRDLLSQAVRVVLGLTGQSLLLAHASETRESISVRNSYLDPLHLLQAELLARSRRCRGDACGGLEQALLVTVAGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: RL6_STREM
Sequence: MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIKVEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ARC_KOCRD
Sequence: MTEPRHESGSAAPQRPATDPVQRQVNLLRDQKRNLDKQAAALASQNEKLVRLLNASRQEIVGLKKTLAAEAEPPATYAVVLQVNHGRRPVGEATGDGPVVTGPTLDVLAAGRRMRVAVSPLVSFGACEPGLGVLLNENYVVVALLEYERTGEVATVKEVVDHDRVLTVGRSDEERVLLLSGRLRRERPKPGDAVTVDHRTGFALEPVTRTDVEQLVLEEVPDVSYTDIGGLGPQIEAIRDAVELPHVHPEIFREHGLRPPKGILLYGPPGNGKTLIAKAVARSLAERSAAKAGRSRPEGYFLNIKGPELLDKYVGETERQIRSIFANAREQAARGVPVVVFFDEMDSLFRVRGSGLSSDVETTIVPQLLTEIDGVEQLDNVMVVGATNREDMIDPAVLRPGRLDVKIRIDRPDREGAREIFSLYLTPDLPLRDEDVARAGSRALAAEELVAAAVQRMYAREPETEFLTIGYRNGTSETLYFSDYASGAVIRNVVDRAKKQAIKTLLTTGRRGITAEHLVAAVDEEFHEQQDLPDTEDSEDWARLTGRRGDTIDSVHMASHRPQGEPGPGATP
What are the official names of this protein?
AAA ATPase forming ring-shaped complexes, ARC.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: KTI12_YEAST
Sequence: MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHSDESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVKNLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAILTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQVLDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTLAQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN
What is the function of this protein?
Elongator complex-associated factor that is not a structural subunit but rather transiently contacts the complex.  Regulates elongator complex gamma-toxin target (TOT) activity, resulting in G1 block by Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin), probably through regulation of the ELP1/IKI3 subunit phosphorylation state.  Required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA.
What are the official names of this protein?
Protein KTI12, Gamma-toxin target protein 4, Killer toxin insensitivity protein 12.
What is the protein family that this protein belongs to?
Belongs to the KTI12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: INS_CROAT
Sequence: APNQRLCGSHLVEALFLICGERGFYYSPRSGIVEQCCENTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRE26_CAEEL
Sequence: MFIKLSSTNSTSIFWLPIFFYNEPYWAQCAISSAELPFYMLSAYVVFVSCRIMLKIQLFHDNLMYIGVPMFGSWFLLIAGKLITILYRVRILNVESVKIHENWVFWTDEPEKMLNVQSLDGLVPLLVAGFLEIHFGFSVIFVGLAIVTERVIASMLIDNYEQSTSLLIPISFIIIYQFLAISISLGILFNILGLYVLNASWILCILIGTIMYYYIRKINTKWLQEMQNPNRKRVFTVSQQFQVRENLGAIAIGKRLVFVVLATIVVMGFGIVALVLEITVLFFMHFGENTLFCYPLYIFLVVMNGHPAWKQEFRKYFPKIKIFKKVRPGLVSVEIVEDQKKKLSLETDTYFRQLKSAWT
What are the official names of this protein?
Serpentine receptor class epsilon-26, Protein sre-26.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sre family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NFIL3_HUMAN
Sequence: MQLRKMQTVKKEQASLDASSNVDKMMVLNSALTEVSEDSTTGEELLLSEGSVGKNKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKSNVSSFVDEHEPSMVSSSCISVIKHSPQSSLSDVSEVSSVEHTQESSVQGSCRSPENKFQIIKQEPMELESYTREPRDDRGSYTASIYQNYMGNSFSGYSHSPPLLQVNRSSSNSPRTSETDDGVVGKSSDGEDEQQVPKGPIHSPVELKHVHATVVKVPEVNSSALPHKLRIKAKAMQIKVEAFDNEFEATQKLSSPIDMTSKRHFELEKHSAPSMVHSSLTPFSVQVTNIQDWSLKSEHWHQKELSGKTQNSFKTGVVEMKDSGYKVSDPENLYLKQGIANLSAEVVSLKRLIATQPISASDSG
What is the function of this protein?
Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters.  Represses transcription from promoters with activating transcription factor (ATF) sites.  Represses promoter activity in osteoblasts (By similarity).  Represses transcriptional activity of PER1 (By similarity).  Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity).  Activates transcription from the interleukin-3 promoter in T-cells.  Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity).  Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity).  Protects pro-B cells from programmed cell death (By similarity).  Represses the transcription of CYP2A5 (By similarity).  Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2 (By similarity).  Required for the development of natural killer cell precursors (By similarity).
What are the official names of this protein?
Nuclear factor interleukin-3-regulated protein, E4 promoter-binding protein 4, Interleukin-3 promoter transcriptional activator, Interleukin-3-binding protein 1, Transcriptional activator NF-IL3A.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. NFIL3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KV6AA_MOUSE
Sequence: QILLTQSPAIMSASPGQKVTMTCSASSSVSYMHWYQQKSGTSPKRWIYDTSKLASGVPARFXGSGSATSYSLTITSMQAEDAATYYCQQWSSNPLTFGSGTKLEXKR
What is the function of this protein?
Anti-2-phenyl oxazolone (PHOX) Antibody.
What are the official names of this protein?
Ig kappa chain V-VI region NQ5-78.2.6.
Protein: ATPG_OCEIH
Sequence: MASLRELKGRIESTKKTKQITGAMQLVSASKMSKAEQNARGFVPYADKLQEVVSSIANANTDAQHPMLMKREVKKTGYLIITSDRGLVGAYNSHILKNLVNTIEKNHTSKDEYTIIVLGRKGYDYCRKRGLPVSKSVLGVPDHPTFADVKELASETVQMYADGDIDELNIIYNHYVSAISQVVTNKQLLPIDNLDESGAATSDYEFDPNQEQILEVLLPQYAESLIFGALLDGKASEHAASMTAMRSATDNASDLIDDLSLSYNRARQAAITQEITEIVGGVAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL11_SHESW
Sequence: MAKKIDAYIKLQVKSGSANPSPPVGPALGQKGVNIMEFCKAFNARTEKMEKGMPIPVVITVYSDRSFTFETKTPPASFLLKTAAGLKSGSPRPNTQKVGTIARAKIQEIAETKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SYM_BURCJ
Sequence: MSASDLTSVQAAAPQGSRQILVTSALPYANGQIHIGHLVEYIQTDIWVRALRMHGHEVYYIGADDTHGTPIMLRAEKEGLTPKQLIDRVWTEHKRDFDSFGVSFDNFYSTDSDENRVLSEKIYLALQEAGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDNCEVCGSTYLPTELLNPYSVVSGATPVRKTSKHYFFRLSDPRCESFLREWVSGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCERNGIDFDAWIRPGSKAEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLRDAIPQIAASYEAREYGRALRHTMELADEVNAYVDGAKPWDLAKDPANAVALHETCSVSLEAFRLLSLALKPVMPRVAAAVEAFFGIAPLAWADAAKPLSSAQPIKAYQHLMTRVDAKQIEALLAANRDSLQADAAGAAAGGANAAKDAKSNAKANAKPAVVNGADDAPISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYILEPHSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.