PharMolix/UniProtQA huggingface dataset:
Protein: DAPF_CAMJ8
Sequence: MKFYKYCASGNDFVITNADRKEDRSALAKELCNRYEGIGADGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFVHHINKINPNMSFLTGAGVIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCNTGVPHLVHFCQNLDEFDTMLCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFAYKNEELFFEGKVKYCFEANYNFS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_RICCN
Sequence: MANNVMDSSFKKEVLESDLPVLVDFWAEWCGPCKMLTPIIDEISKELQGKVKVLKMNIDENPNTPSEYGIRSIPTIMLFKNGEQKDTKIGLQQKNSLLDWINKSI
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: H3I01_CYRHA
Sequence: MKASMFLALAGLVLLFVVGYASESEEKEFPRELLSKIFAVDDFKGEERGCKGFGDSCTPEKNECCPNYACSSKHKWCKSI
What is the function of this protein?
Lethal neurotoxin.  Selectively blocks tetrodotoxin-sensitive voltage-gated sodium channels (Nav).  Does not affect tetrodotoxin-resistant voltage-gated sodium channels or calcium channels (By similarity).
What are the official names of this protein?
Mu-theraphotoxin-Hhn2q, Mu-TRTX-Hhn2q, Hainantoxin-III-9, HNTX-III-9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NIP41_ORYSJ
Sequence: MTTDHAGKKVDVVVVGNVDGEHVGVEQARHDLHEEAAAAAAADHHATRGLAIGFLIREVMVEGLASFLVVFWSCVAALMQEMYGTLTFPMVCLVVAMTVAFVLSWLGPAHFNPAVTITFAAYRRFPVWPKLPLYVAAQLAGSLLACLSVNAVMRPRHDHFYGTAPVVVHGTRLPFLMEFLASAVLMIVIATVATDGTAGKTVGGIAIGAAVGGLGLVIGPVSGGSMNPARTLGPAIVLGRYDGVWIYVVAPVAGMLVGALCNRAVRLSHRIVAFLCGTSVGIAGSP
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin NIP4-1, NOD26-like intrinsic protein 4-1, OsNIP4;1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECF_METCA
Sequence: MALLKLDIADVRNIESASLSPGEGLNLLFGANGSGKTSLLEAIYLLSRGKSFRSPQSGRIIRFDRPCLTVSGSIGRPGAGIAVGVRLGRSEKEVRVGGRSCDSSAQLIRLFPAVLIHPASVALLEGPPRWRRQMLDWGVFHVEQGYLDLLRRFSRTLEQRNAVLRGDAPGSSLAAWSGELARWGTMIAELRSSYLDRIRMHFGEMVSALLGRTDVELVVRPGWRAGWSYADALAASQPTDRRLGYTEPGPQKGDFAVLVGGRPARDYLSRGQLKLLTYALLLAQAGLLEADQPGRVCLLVDDIASELDSRNQERLLSLVKSTGLQSFVTFSGATQGVAAVVGRTARVFHVEQGRIRTGS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_LACAC
Sequence: MAEQISSAKAEARTVRIAPRKARLVIDLIRGKSVAEALAILEFTPRAASPIVEKVLRSAIANAEHNYDLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSEKND
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RR11_CUSGR
Sequence: MVKLIPRLSSRRNGRIRLRKNTRKISQGVIHIQASLQNTIVTVTDVRGRVVSWASAGSAGFKGTTRRTPFAAQTAATNAIRTAINHGMREADVLIKGPGLGRDAALRAIRRSGIRLELILDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
Plastid 30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ISPH_SACD2
Sequence: MEIKLANPRGFCAGVDRAIDIVNRALDVFGAPIYVRHEVVHNKFVVERLKERGAIFVDELEAVPDDVIVIFSAHGVSQAVRQEADRRGLKVFDATCPLVTKVHMEVAKYSNDGCECVLIGHEGHPEVEGTMGQYDTANGGAIYLVEDESDVEQLEVRDPTRLSYVTQTTLSMDDTARVIDSLRAKFPHITGPRKDDICYATQNRQDAVKQLALECDLVLVVGSPNSSNSNRLRELAERCGTAAYLIDGPEDLDKSWFANCKNIGITAGASAPEVLVRDVIEGLKAIGASAPVELQGQEENISFSLPKELRV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ILB6_CAEEL
Sequence: MHSIVALMLIGTILPIAALHQKHQGFILSSSDSTGNQPMDAISRADRHTNYRSCALRLIPHVWSVCGDACQPQNGIDVAQKCCSTDCSSDYIKEICCPFD
What are the official names of this protein?
Putative insulin-like peptide beta-type 6.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: WDR12_AEDAE
Sequence: MALKITGKSEGQLQLHLYTKQKQFAVPDVPYSIRANVSNKELNVLINTLLKDSGNSEAGKVEFDFLLNGEFVKIPLGQHLKEREISFEDTVELEYVERYPAPEPQDCLLHDDWVSAVEAKDNWILTGCYDNTLNIWTTKGKHKLTIPGHIAPVKGVTWISLDEEKGVFASASQDQTVMLWEWNVKANSVECVQVCKGHERGVDCIAANRSKTRMATGSWDTMLKIWSTDVRNDGDSQPSTSKRQKLDTEKARTPVLTLAGHRECISGVQWIDDNTLVTSSWDHTIKIWDLALSGIKSEICGHKSFFDLSYSHLNGLIIAASPDKNLRLYDPKSNQGTIVKNTYLGHTQWVQSVRWSTTNEYLFVSGAYDNHVKLWDYRSPKAPIFELIGHEDKVLACDWSNPKFILSGGSDNSVRVFKSKIAIGEQK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: GSA_LEPCP
Sequence: MATPVSSNAELFERAQRSIPGGVNSPVRAFRAVGGTPRFIARAQGAYMWDAEGKQYIDYIGSWGPMILGHGHPAVLAAVQKAATEGFSFGAPTEREVELAETILALVPSCEQIRLVSSGTEAAMSAIRLARGATGRSKLIKFEGCYHGHADALLVKAGSGLATFGNPTSAGVPPEVVQHTLVLTYNDIEQLEEAFKIHGPELACVMIEPIAGNMNFVRATVPFMKRIRELCTQHGALLVFDEVMCGFRVALGSAQSLYAQAIPGFAPDVSVFGKVIGGGMPLAAFGASRKIMSLLAPLGPVYQAGTLSGNPVATACGLATLREISQPGFFEALGARTRRLVDGLSAAAADAGVPFVGDCQGGMFGFFFPRNRGEGLPQNYATVMATDQARFNSFFHGLLDRGVYLAPALYEAGFVSAAHSDADIDATVAAARAALQP
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLA2_GEOKA
Sequence: MTTGVQTLKNYIGGQWVESRSGKTEAVPNPATGEVLAYVPISSREELDEAVRAAKEAFKTWRKTPVPRRARILFKYQQLLVEHWEELARLVTLENGKSYNEAYGEVQRGIECVEFAAGAPTLMMGRQLPDIATGIESGMYRYPIGVVGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFKEAGLPDGVLNIVHGAHDVVNGLLEHPDVKAISFVGSQPVGEYVYKTAAAHGKRVQALTGAKNHSIVMPDADLNVAVREIINAAFGSAGERCMAASVVVAVGEIADELVEKLVAAANELKIGNGLEESVFLGPVIREAHKQRTVKYIELGEKEGAILVRDGRKDAAVQDNGYFIGPTIFDRVTTDMTIWKDEIFAPVLSIVRVETLDEAIEVANKSPFANGACIYTRDGGNVRKFREEIDAGMLGVNLGVPAPMAFFPFSGWKNSFYGDLHANGMDGVEFYTRKKMMTSRW
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 2, MSA dehydrogenase 2, Methylmalonate-semialdehyde dehydrogenase 2, MMSA dehydrogenase 2, MSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: CLSA_ECOSM
Sequence: MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y584_METJA
Sequence: MKMDVMSFIMNIINVMINTIIDYLNVNRVLALLMAFLMAGGIASMINKNFIIKYFGSNTPKYISYTVAAVSGSLLAVCSCTILPLFASIYKRGAGIGPATTFLFSGPAINVLAIFYSAALLGWDIGFLRAVFAVVVSILIGLSMEIIFKSHEKKRALRVPKADKISDRPLYQTITFFALQFIMLLVITASPKLFPTLSMPLYDGFLLKHLLFIILGIILAVTTKIWFKDEEIKNWLRESFTLLKIVFPLLIIGVAIAGAIKAIIPPSYIATYVGGNSITANFIASFIGALMYFATLTEVPIIKALMELGMGVGPAMALLLAGPSLSIPTVLTISKVLGKTKALTYLGLVVIFSTICGYIAGIILR
What are the official names of this protein?
UPF0718 protein MJ0584.
What is the protein family that this protein belongs to?
Belongs to the UPF0718 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDK_GLUOX
Sequence: MALERTLSIIKPDATKRNLTGKINAVFEGAGLRIVAQKRIQLTEKQAGAFYAVHKERPFYGSLVSSMIAEPVVVQVLQGENAVAKNREVMGATNPADAAEGTVRKLFAESIEANSVHGSDSLENAKNEISFFFAETEILP
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXUT_ECO57
Sequence: MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH
What is the function of this protein?
Transport of aldohexuronates such as D-glucuronate and D-galacturonate.
What are the official names of this protein?
Hexuronate transporter, Aldohexuronate transport system.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IGS11_MOUSE
Sequence: MTRRRSAPASWLLVSLLGVATSLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPQCQIQGSQDLGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALISGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHRNTESFNHFSDLRQSFSGNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVLPRNNGSVSRKPWPQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV
What is the function of this protein?
Functions as a cell adhesion molecule through homophilic interaction.  Stimulates cell growth (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 11, IgSF11, Brain and testis-specific immunoglobulin superfamily protein, Bt-IGSF.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SMG_SHEB2
Sequence: MFDILMYLFENYVHSEVELLVDEDELTKELTRAGFHQSEILKALTWLERLAELQEGDKPYLCNHDQHSFRIYTKDEMDKLDVESRGFLLFLEQVKVLNVETREMVIDRVMELDEPTLILEDLKWVILMVLFNAPGHESAYEQMEDLIFEQPEGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: PLSX_POLAQ
Sequence: MSVTLAIDAMGGDHGVVVTVPAACDFLEKHSDVKIILVGDPDLIKQVLDKSPKAPIERIQIIAASEVVLMDDPIEIALRRKKDSSMRVAIVQVKEGAADAVVSSGNTGALMAISRYILKTLDGVDRPAIATAIPNELGLGTTMLDLGANADCEPMHLVQFAQMANVMVQVVDGKPNPSIGLLNIGEEVIKGNEVVKQTSELLRQTNLNFYGNVEGNDIFKGTTDIVVCDGFVGNVVLKASEGLAKMMSGLIRKEFNRSLFTKLMAVCAMVPLLRVRKRVDHRRYNGAVLLGLRGCVIKSHGSADRFAFGFALERAYEASKNHMVERIAAAFVVETTE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CNTRL_HUMAN
Sequence: MKKGSQQKIFSKAKIPSSSHSPIPSSMSNMRSRSLSPLIGSETLPFHSGGQWCEQVEIADENNMLLDYQDHKGADSHAGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVGTGANSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSMADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGVGLKYSASTPVRKPRPGQQDGKEGSQPPPASGYWVYSPIRSGLHKLFPSRDADSGGDSQEESELDDQEEPPFVPPPGYMMYTVLPDGSPVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSADSASSPSLSQLESSLTEDSQLGQNQEKNASAR
What is the function of this protein?
Involved in cell cycle progression and cytokinesis.  During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission.
What are the official names of this protein?
Centriolin, Centrosomal protein 1, Centrosomal protein of 110 kDa, Cep110.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody, Midbody ring.
Protein: CACB1_HUMAN
Sequence: MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR
What is the function of this protein?
Regulatory subunit of L-type calcium channels (PubMed:1309651, PubMed:8107964, PubMed:15615847).  Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity).  Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane (PubMed:15615847).  Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit (PubMed:1309651).  Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (PubMed:8107964).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel beta subunit family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.
Protein: MOAA2_MYCBO
Sequence: MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLRVSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTGGEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVKVNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHAFCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGHGINAPDFIQPDRPMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase 2, Molybdenum cofactor biosynthesis protein A 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RNZ1_HUMAN
Sequence: MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSMVSKQPIEIYGPVGLRDFIWRTMELSHTELVFHYVVHELVPTADQCPAEELKEFAHVNRADSPPKEEQGRTILLDSEENSYLLFDDEQFVVKAFRLFHRIPSFGFSVVEKKRPGKLNAQKLKDLGVPPGPAYGKLKNGISVVLENGVTISPQDVLKKPIVGRKICILGDCSGVVGDGGVKLCFEADLLIHEATLDDAQMDKAKEHGHSTPQMAATFAKLCRAKRLVLTHFSQRYKPVALAREGETDGIAELKKQAESVLDLQEVTLAEDFMVISIPIKK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 1, Deleted in Ma29, ElaC homolog protein 1, Ribonuclease Z 1, RNase Z 1, tRNA 3 endonuclease 1, tRNase Z 1.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: UCMA_SPAAU
Sequence: MSWTRVVVLSLLTTLLFLTFSSVVDSAAVRDDSKAGHPKGPARQVFVPESEASNFFKRRSRRSPRSYAELQAEQRVKIAANERWREYNEEQRNEHENYAEEARDESDERSRETHEQIREYHYDGLYPRYHWFH
What is the function of this protein?
May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
What are the official names of this protein?
Unique cartilage matrix-associated protein.
What is the protein family that this protein belongs to?
Belongs to the UCMA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CYSC_CLOK5
Sequence: MNVKSTNISWHRALVDREMREKLLGQNGILIWFTGLSGSGKSTIASELEMRLYNMGRLTYLLDGDNVRHGLNSNLGFTKEDRIENIRRTAEVCKLFVDSGIITISTFISPFKDDRDKVRKLLGKDFVEVYVDCPLEVCESRDPKGIYKKARNGEIKDFTGVDSPYEVPDNPEIVVSTNLDTVQQCVNKILDFLSCKVQE
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: RK23_COFAR
Sequence: MDGIKYAVFTDKSIRLLGKNQYTFNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL20_BACHK
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ARGO_SHIFL
Sequence: MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YSAA_ECOLI
Sequence: MNRFIIADATKCIGCRTCEVACAVSHHENQDCAALSPDEFISRIRVIKDHCWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQTRCIGCKSCMLACPFGAMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV
What are the official names of this protein?
Putative electron transport protein YsaA.
Protein: THIK_SALG2
Sequence: MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTHRIVLRRHHDPDAPPAHFLRHYRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDAEELAALLYHLQQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.