PharMolix/UniProtQA huggingface dataset:
Protein: SPSA_SOLTU
Sequence: MAGNDWINSYLEAILDVGPGLDDKKSSLLLRERGRFSPTRYFVEEVITGFDETDLHRSWIRAQATRSPQRRNTRLENMCWRIWNLARQKKQLEGEQAQWMAKRRQERERGRREAVADMSEDLSEGEKGDIVADMSSHGESTRGRLPRISSVETMEAWVSQQRGKKLYIVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVSSPEVDWSYGEPTELAPISTDGLMTEMGESSGAYIIRIPFGPREKYIPKEQLWPYIPEFVDGALNHIIQMSKVLGEQIGSGYPVWPVAIHGHYADAGDSAALLSGALNVPMLFTGHSLGRDKLEQLLAQGRKSKDEINSTYKIMRRIEAEELTLDASEIVITSTRQEIDEQWRLYDGFDPILERKLRARIKRNVSCYGRFMPRMAVIPPGMEFHHIVPHEGDMDGETEGSEDGKTPDPPIWAEIMRFFSNPRKPMILALARPDPKKNLTTLVKAFGECRPLRDLANLTLIMGNRDNIDEMSSTNSALLLSILKMIDKYDLYGQVAYPKHHKQSDVPDIYRLAAKTKGVFINPAFIEPFGLTLIEAAAYGLPMVATKNGGPVDIHRVLDNGLLVDPHDQQAIADALLKLVADKQLWAKCRANGLKNIHLFSWPEHCKTYLSRIASCKPRQPRWLRSIDDDDENSETDSPSDSLRDIHDISLNLRFSLDGEKNDNKENADNTLDPEVRRSKLENAVLSLSKGALKSTSKSWSSDKADQNPGAGKFPAIRRRRHIFVIAVDCDASSGLSGSVKKIFEAVEKERAEGSIGFILATSFNISEVQSFLLSEGMNPTDFDAYICNSGGDLYYSSFHSEQNPFVVDLYYHSHIEYRWGGEGLRKTLVRWAASIIDKNGENGDHIVVEDEDNSADYCYTFKVCKPGTVPPSKELRKVMRIQALRCHAVYCQNGSRINVIPVLASRSQALRYLYLRWGMDLSKLVVFVGESGDTDYEGLIGGLRKAVIMKGLCTNASSLIHGNRNYPLSDVLPFDSPNVIQADEECSSTEIRCLLEKLAVLKG
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).
What are the official names of this protein?
Probable sucrose-phosphate synthase, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: ANX2_ARATH
Sequence: MNEKLRILFSFLCFFYVLLVSPSQSNGQDISLSCGASEPAVDQDKKKWEPDTKFLKTPNTVHAPATYQDPSLLSTVPYMTSRIFTAPATYEIPVKGDKRHMLRLHFYPSTYTGLNILDSYFSVAANDLTLLSNFSAAITCQALTQAYLVREYSLAPSEKDVLSIIFTPSDKHPKAFAFINGIEVIPMPELFDTASLVGFSDQTSDTKTANLQTMFRLNVGGQDIPGSQDSGGLTRTWYNDAPYIFSAGLGVTLQASNNFRIDYQKMPVSTAPADVYKTARSQGPNGDINMKSNLTWMFQVDTNFTYIMRLHFCEFQLAKINQKVFNIFINNRTAQGDTNPADILGWTGGKGIPTYKDYAIYVDANTGGGGEEISLQMTPSTFGQPEYYDSQLNGLEIFKIDTMKNLAGPNPKPSPMQANEDVKKDFQGDKRITAFVIGSAGGVAAVLFCALCFTMYQRKRKFSGSDSHTSSWLPIYGNSHTSATKSTISGKSNNGSHLSNLAAGLCRRFSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDGGTKVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLREHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEVLCARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDPNLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVLWNLEFALQLQETADGSRHRTPSNGGGSVDLGGGGGGVTVNISAGESDLGDDLSSEENSGIFSQIVNPKGR
What is the function of this protein?
Receptor-like protein kinase that controls pollen tube behavior by directing rupture at proper timing to release the sperm cell.
What are the official names of this protein?
Receptor-like protein kinase ANXUR2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HIS1_ECODH
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FARS_ARTAN
Sequence: MSTLPISSVSFSSSTSPLVVDDKVSTKPDVIRHTMNFNASIWGDQFLTYDEPEDLVMKKQLVEELKEEVKKELITIKGSNEPMQHVKLIELIDAVQRLGIAYHFEEEIEEALQHIHVTYGEQWVDKENLQSISLWFRLLRQQGFNVSSGVFKDFMDEKGKFKESLCNDAQGILALYEAAFMRVEDETILDNALEFTKVHLDIIAKDPSCDSSLRTQIHQALKQPLRRRLARIEALHYMPIYQQETSHNEDLLKLAKLDFSVLQSMHKKELSHICKWWKDLDLQNKLPYVRDRVVEGYFWILSIYYEPQHARTRMFLMKTCMWLVVLDDTFDNYGTYEELEIFTQAVERWSISCLDMLPEYMKLIYQELVNLHVEMEESLGKGGKNISNSLCQGRWQKELGSQITLVETKMAKRGVHAQPLEEYMSVSMVTGTYGLMIARSYVGRGDIVTEDTFKWVSSYPPIIKASCVIVRLMDDIVSHKEEQERGHVASSIECYSKESGASEEEACEYISRKVEDAWKVINRESLRPTAVPFPLLMPAINLARMCEVLYSVNDGFTHAEGDMKSYMKSFFVHPMVV
What is the function of this protein?
Sesquiterpene cyclase catalyzing the production of beta-farnesene from farnesyl diphosphate.  Unable to use geranyl diphosphate as substrate.
What are the official names of this protein?
(E)-beta-farnesene synthase, AaFS, Terpene synthase 10.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AES_ECOK1
Sequence: MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGAIAEQRQYYTLERRFWNVGAPEMATRAYRVPTKYGQVKTRLFYPQPDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSCLLYQTLAAHQQPCEFKLYSGMLHAFLHYSRMMKTADEALRDGAQFFTAQL
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA2_GEOTN
Sequence: MRSYERSKAAYEEAVTLMPGGVNSPVRAFKSVGMTPIFMARGQGAKIYDIDGNEYIDYVLSWGPLILGHADPQVVEALKRVAEQGTSFGAPTLLENELAKLVIERVPSVEIVRMVNSGTEATMSALRLARGYTKRNKIIKFEGSYHGHGDSLLIKAGSGVATLGLPDSPGVPQSVAQHTITVPYNDLDSVRYAFERFGEDIAAVIVEPVAGNMGVVPPVPGFLEGLRDVTKQYGALLIFDEVMTGFRVDYHCAQGYYGVEPDLTCLGKVIGGGLPVGAYGGKAEIMEQVAPSGPVYQAGTLSGNPLAMTAGYETLRQLTPETYKEFRRKAARLEEGLHQAAEKYEIPHTINRAGSMIGFFFTNEPVINYETAKTSDLELFAAYYREMANEGIFLPPSQFEGLFLSTAHSDEDIEYTIAAAERVFARLRG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_STRPD
Sequence: MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAGWVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAIVWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEVKSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFALASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDVIDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: USPA_SHIFL
Sequence: MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein A.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BORPE
Sequence: MRHYEVVFIVHPDQSEQVPAMVERYQALVTGQSGTVHRLEDWGRRQLAYPIQKLVKAHYVCMNIECGQATLDELEHSFRYNDAVLRHLVIKTKKAPAAPSIMMKSVEREEARKASAEAAATATAAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BIOB_FRAP2
Sequence: MTLEQIKEIYSRPLTELILQALEIHNKNFGNDIELCSLKSIKTGTCPEDCKYCPQSGHYNTSIEKHKLLDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKDFDQVAEIITEVKNLGLETCVTLGSINAEEATKLKEAGLDYYNHNLDTSREFYPEIITTRKFEERIETIRNVANADINVCCGGILGMGESLDDRFNLLLELLQLPAAPKSIPINTLIPVKGTPLGDKYTDAQIDSFELVRFIATTRILFPQARLRLSAGRENMSLETQTLCFLAGINSIFYGNKLLTENNATINSDNFLLAKLGLESNVELC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KI2S5_HUMAN
Sequence: MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA
What is the function of this protein?
Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles.  Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:28685972, PubMed:18624290, PubMed:18682925).  Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691).  Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry (PubMed:28685972).
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DS5, CD158 antigen-like family member G, Natural killer-associated transcript 9, NKAT-9.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Protein: RS10_HALMA
Sequence: MSQQARVRLAGTSPEDLDDICADVREIANKTGVELSGPVPLPTKTLEVPSRKSPDGEGTATWEHWEMRVHKRLIDIDADERALRQLMRIQVPNDVSIEIVLED
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10, HmaS10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YES_CANLF
Sequence: MGCIKSKEDKGPAIKYRNTPEPVSVSHYGAEPTQATPWPSSSGWGTAFNFSSLSMTGFGGSSGVTPFGGASSSFSVVPSPYPAGLTGGVTIFVALYDYEARTTEDLSFKGGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIAAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHSTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKLGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTAAEPQYQPGENL
What is the function of this protein?
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.  Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.  Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.  Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts.  Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration.  Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration.  Plays a role in cell cycle progression by phosphorylating the cyclin dependent kinase 4/CDK4 thus regulating the G1 phase.  Also involved in G2/M progression and cytokinesis (By similarity).  Catalyzes phosphorylation of organic cation transporter OCT2 which induces its transport activity (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, p61-Yes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.
Protein: EFEO_YERPA
Sequence: MSIWFFRRTALHAALLSLPVFAISAQAADIQQVKITVNDKQCEPMALTVPAGKTQFIVHNVSQKGLEWEILKGVMVVEERENIAPGFTQKMTANLEPGEYDMTCGLLSNPKGKLTVTVAAGEQAPVKPDAMALVGPIAEYKVYVTQEVAQLVSQTKAFTDAVKAGDLALARKLYAPTRQHYERIEPIAELFSDLDGSIDAREDDFEQKSADPKFTGFHRLEKILFGDNTTKGADKFADLLYQDTLELQKRIAGLTFAPNKVVGGAAGLIEEVAASKISGEEDRYSRTDLWDFQANVDGAQKIVNLLRPLLEKADKPLLQKIDANFNTVDSVLAKYRTKEGYESYEKLTDADRNAMKGPITALAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SPH24_ARATH
Sequence: MINSSRINLNSYFCSIFIVSIVVISLICSEALQIQEAKEPIRGHLTRVTIQNDNDYLLGIHCKSRDDDLGFHILAKGELFGWKFHVNFCYSTLYFCGFSQGQMKKGVFEIYRANRDFYRCANCTWKAEKDGIYGYSEDPVKGYLFYNWLK
What are the official names of this protein?
S-protein homolog 24.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: IL13_MACMU
Sequence: MALLLTTVIALTCLGGFASPSPVPRSTALKELIEELVNITQNQKAPLCNGSMVWSINLTAGVYCAALESLINVSGCSAIEKTQRMLNGFCPHKVSAGQFSSLRVRDTKIEVAQFVKDLLVHLKKLFREGRFN
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection.  Synergizes with IL2 in regulating interferon-gamma synthesis.  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6.  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
What are the official names of this protein?
Interleukin-13, IL-13.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_PECCP
Sequence: MLANIIRIATRQSPLALWQARYVQQCLNHLYPDLHVELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLEGRADIAVHSMKDVPVEFPDGLGLTTICERDDPRDAFVSNRYDSLEQLPEGSCVGTSSLRRQCQLRARRPDLVIRDLRGNVGTRLAKLDNGEYDAIILAVAGLKRLGLEERIRCALSPEESLPAVGQGAIGIECRLNDDRIRQLLAPLNHPATAARVQAERAMNVRLEGGCQVPIGSYAELEGDTLWLRALVGAPDGSQMIVGERRGNVSDAEQIGIALAEELLAKGASAILQAVYHESSSS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TRMA_ACTP2
Sequence: MNLPIEQYADLLAEKAKNLTALLAPFNPPELEVFESETGHFRMRAEFRVWHDTNEVGENELYHIMFDQETKQRYCVEQFPIANHLINKMMSSLLAEIKGNELLTRKLFQVDYLSTLSGEIAVSMLYHKKLNEEWQAEAAALKARLEHQGFKVQIIGRATKQKIALDRDYVEEVLPVDGRNLIYRQVENSFTQPNAKMNIKMLEWARSCTRHSSGDLLELYCGNGNFSIALAENFRKVLATEISKSSVQSAQYNIEQNGIDNLQIIRMSAEEFTQAMNGVREFNRLKGIDLKAYDCNTIFVDPPRAGLDQDTLNMVQAYERILYISCNPYTLAENLRQLSLTHRIERAALFDQFPYTHHVESGVWLIRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: ALF1_STAAB
Sequence: MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGINEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTADYLADKGVVPFLKVDKGLAEEQNGVQLMKPIDNLDSLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFEVAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTEANLYKDLAEHPNVVRIVVLSGGYSREKANELLKDNAELIASFSRALASDLRAGQSKEEFDKALGDAVESIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: PFKA_WOLSU
Sequence: MRIGLVCSGGDCAGMNPATKKFVEYSLELGYEPYFIREGLEGLIEGKIEPATLKEVSGILHKGGTILQSSRSKRFFDPAFRLQAYQNLQRHSIEALVTLGGDGSFRAMEVLAKEHSLLYAGIPATIDNDIRASDYALGVDSALNVILESTDRLRDTAESFRRAFVVEVMGRDCGYLALASAIACGAEVCIIPEMGYSLQSLGARLKEELGTGKRRYVLAIVSEGAKASSEVVSWLKEEVGIETRITILGHVQRGGSPSVYDRLMGFRFMQKALDSLSLGKSGVVVLREGRVEFLSSQEASSAPASLPLDMVRLASRLMF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDA_STAES
Sequence: MTNINVRNYIDESYGLFINNEFQASDSGETLTVSNPANGEDLAKVARAGKKDVDKAVQAAHDAFDSWSKISKEERADYLLEISRRIHEKTEHLATVESLQNGKPYRETSTIDVPQAANQFKYFASVLTTDEGSVNEIDQNTMSLVVNEPVGVVGAVVAWNFPILLASWKLGPALAAGNTVVIQPSSSTPLSLIELAKIFQEVLPKGVVNVLTGKGSESGDAIFHHEGVDKLSFTGSTDVGYGVAQAGAERIVPTTLELGGKSANIIFDDANLEQVIEGVQLGILFNQGEVCSAGSRLLVQSSIYDELLPKLKEAFENIKVGDPFDEDTKMSAQTGPEQLDKIESYIKIAEEDDKANILTGGHRITDNGLDKGYFFEPTIIEINDNKHQLAQEEIFGPVVVVEKFDDEQEAIEIANDSEYGLAGGIFTTDIHRALNVAKAMRTGRIWINTYNQIPAGAPFGGYKKSGIGREVYKDAIKNYQQVKNIFIDTSNQTKGLY
What are the official names of this protein?
Putative aldehyde dehydrogenase AldA.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ACCA_NITSB
Sequence: MATYLDFEQKIKEIENELEAAKARGDTAAIEIFEKDLQKEASKTYKNLSDYQKLQLARHPDRPYALDYIRLILDDAYEIHGDRCFRDDPAILCYLGYIDGQKTLVIGEQKGRGTKNKLKRNFGMPHPEGYRKALRAAKMAEKFGLPILMLIDTPGAYPGIGAEERGQSEAIARNLIEFSMLDTPTISIVIGEGGSGGALAIGVADKLAMLKYSVFSVISPEGCAAILWNDPAKVEQATKALKITAEDLKELGLIDDIIDEPFMGAHRDKEGAAKALKEYYLQNIRELMQMDPKERLEKRYEKLMKMGRFKE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_VARPS
Sequence: MQKFTVHKGLVAPMDRENVDTDAIIPKQFLKSIKRTGFGQNLFDEWRYLDAGFPGQDPQSRKPNPDFVLNQPRYAGASILLARKNFGCGSSREHAPWALDQYGFRAIIAPSYADIFFNNSFKNGLLPIVLPEAQVAQLFDETFAFPGYTLTIDLERQVVVKPDGGEFAFDVQAFRKYCLINGLDDIGLTLRHKDKIKAFEAERLAQKPWLAHTMIS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL6_CITK8
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYVDGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ARG56_NEUCR
Sequence: MYSACAVALRAGARRVVRRVPKSARALPRAAAARRQISTTAARSTDLTTRGMIVQTLSSVGSKREVQQYLSLFTSVSSQRFAVIKVGGAILTDYLDELCAALKFLYTVGLYPVIVHGAGPQLNRLLEDAGVEPQFEEGIRVTDAKTLRVARDLFLQENLKLVNKLEEMGVHAQPLTTGMFRADYLNKEKWGLVGKVTGVNKQAIETAISNGYLPILTSMAETDDGQILNVNADVAAAELARALEPLKVVYLSEKGGLFDAGGQKISAINLDEEYEHLMSQAWVKYGTRLKIKEIKELLDTLPRTTSVAIIHPEELQKELFTDSGAGTLIRRGSKLQASTSLSEFKDLEALKSVLIRDREGPDAKETVEKYLDFLKENPFKAYFDSSMNALAIVLPASEGRQATLATLTITKSGWLTNIADNIFTALKKEHPSLVWTVKEDDENLGWFFDKADGSITRQGDVMFWYGIENGDEIVKLMKDFTENGRAMLGNSNLESRLRQAASKPAAQQVRGYSTLARRPALPKFSISNRRGYLTQTNPNPPVGKQNASMDRPARVALIGARGYTGQELIRLIDSHPNMELHHVSSRELAGKKLEGYNKQEVIYENLSPEDVRDMEKRGEIDCWVMALPNGVCKPFVEAVWEGRKASGHKSVIIDLSADYRFDNKWTYGLPELVQRSNIIQATQIANPGCYATAAQLGISPLVPHLGGMPHVFGVSGYSGAGTKPSPKNDVENLTNNIIPYSLTGHIHEREVSSQLGAEIAFMPHVAVWFRGIHHTISIPLNKSMTSRDIRQLYQDRYAGEKLVKVVGEAPSVKNIGGKHGVEIGGFEVDKSGRRVVICATIDNLLKGAATQCLQNMNLALGYAEYEGIPTM
What are the official names of this protein?
Protein arg-6, mitochondrial.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAGSA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.