PharMolix/UniProtQA huggingface dataset:
Protein: F120C_HUMAN
Sequence: MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLGFRNNRLGNPPLPRNQVGTISAGKPMFSHQVPQKVKYPPPFPVGPNSSLLFSSHALGESHAFSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSSSSDGDEPNGASSDHITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMSTRNHMDITIPPLPPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVLFSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILHRHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQGGKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGSSDGVSKSLELHQGRSRSQVNGNSGALIKEEKSDHRLPAPSQCALSRDSNECNNGNRYLPMNNREKNHLQEQKLETVAQRKED
What are the official names of this protein?
Constitutive coactivator of PPAR-gamma-like protein 2, Protein FAM120C, Tumor antigen BJ-HCC-21.
What is the protein family that this protein belongs to?
Belongs to the constitutive coactivator of PPAR-gamma family.
Protein: MIAB_DEIGD
Sequence: MRAHLITYGCQMNEYDTHLVESQLVSFGADIVSSVDEADFVLINTCAVRGKPVDKVRSLLGDLRKQKAQRPLVVGMMGCLAQLEEGQQIARKFEVDVLLGPGSLLDIGKALETNERFWGLQFKDELHGHIPPPPQGKLQAHLTIMRGCDHHCTYCIVPTTRGPQVSRHPDDILRELDLLLAAGVQEVTLLGQNVNAYGVDQGARLAGYPSFANLLRLVGRSGIRRVKFTTSHPMNFTEDVAAAMAETPAVCEYVHLPVQSGSNRVLRRMAREYTREKYLSHIAEIRRHLPDVVLATDIIVGFPGETEEDFQETLSLYDEVGYDAAYMFIYSARPGTPSYKHFADLPREVKTERLQRLIAKQKEWSARKNAAKVGTIQEVLLRGDAHDAHFLEGHTRGNHPTVVPKAAGASGPGIYRARIEHATPHMLYGRLIGEDGQDLPELPRFNPEAAGLSHPLQMV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_YERPA
Sequence: MHCPFCAAVDTKVIDSRLVSDGSQVRRRRQCLDCNERFTTFEVAELVLPRVIKSDEVREPFNEEKLRRGMLKALEKRPVSSDDVETAISHIKSQLRATGEREVPTKMVGNLVMEALKRLDKVAYIRFASVYRSFEDVREFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS20_AROAE
Sequence: MANSAQARKRARQAVVARAHNGSLRSRLRTAIKAVQKAVVGGDKAAAQATFRTSMSTIDSIADKKIIHKNKAARHKSRLSAAIKAMTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PO5F1_PIG
Sequence: MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGSGIGPGVGPGAEVWGLPACPPPYDFCGGMAYCAPQVGVGLVPQGGLETPQPEGEAGAGVESNSEGASPEPCAAPAGAAKLDKEKLEPNPEESQDIKALQKDLEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLESMFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYSQREDFEAAGSPFPGGPVSFPLAPGPHFGTPGYGGPHFTTLYSSVPFPEGEAFPSVSVTPLGSPMHSN
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').  Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.  Critical for early embryogenesis and for embryonic stem cell pluripotency.
What are the official names of this protein?
POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus.
Protein: HYFE_ECO57
Sequence: MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSIFATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLAALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMENGSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG
What are the official names of this protein?
Hydrogenase-4 component E.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOH2_CERS4
Sequence: MSVLLIALFSLILLLALLGAAGVFTWGERRLLGFLQERLGPNRVGPFGFLQWVADTLKLLTKEDAPPAGADLAAYRLAPALAAFPMLAGFGVVAFAPRLVISDLDVGVLFVMGMLALTVWALVLGAWGSRNRYAMLGGLRAAAQMLAYESFLGLSLMGCVLLAGSFRMGDIVAAQEGGLWFILLQPLGAALFFLAGLAAAHRLPFDLQESEQDLVAGFMTEYSGMSFALFFLGEYLAILLVAALFTTLFLGGWAGPILPGPIWFGLKVAAISVVFVWLRAALPRPRYDQLISFAWKVALPLALLNLLVTAWIAVGRAA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_BACC3
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LIPB_ECO55
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIVPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2895_AROAE
Sequence: MPSFDIMSEVDLPSLKNAVDVANRKISGRYDFKGSDARVEQGEKVLTLFGDSDFQIDQMRQILLPEMTSKKIDVRCLEYGDLQKIGGNKLKQELKVRVGVEQDLAKKIVKLLKDSKLKVQAAIQGEAIRVSGAKRDILQEAIALVKKEITDFPLQFGNFRD
What are the official names of this protein?
UPF0234 protein AZOSEA28950.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: C3H48_ORYSJ
Sequence: MADSEDGDHVATTTTEQRYDDDGHLVPSSGGQEEEGSGGRDVVVPGGHVAEDYRSGVGVPVGRDAGGATSSPPQPVHVTPSILVGSIHAPVFQGELVGMKFGVGSGSMGAGTSATRRLPATGFGALPTSSMAEDSADHADDDHLAEEEEEEEEEHYIDDGPLVPSSGGQEEEGSGGRHVFVPGGHDGEEDHPDDLVADLDLDLLVDGVVGPVPGGHLNADAPAFVPTTRGRQDLYSALSSSAPAAGYRYRHYITSSALAEAGHVSPFLGLPYATAFDSPLDRELVGPSSAPPPCSAASRAWLVRCSSPLSDSEWTRRSILAREAAHTPASTVTGRGRFEFVPIPGAPYAPPPSFAPIAAGAGPAARPLQQLAFGLEEHKTKLCAEYYSRGLGCPRGNTCKYAHGEDDLRLVVAVSSLADAGEGSSSSDSSFAALGGEDKYKTKLCKTFTSGGLCLFAANCRFAHGEVELGKKEPCWYFFSGQTCPRGDTCGFRHSY
What are the official names of this protein?
Putative zinc finger CCCH domain-containing protein 48, OsC3H48.
Protein: PHT19_ORYSJ
Sequence: MAPRIRVLAALDQARTQYYHFKAIVIAGMGLFTDSYDLFCISPVMKIFGRVYYAPSGSVDGSGSGPGVTPPAVVSATVGVALLGAVAGNVVFGALGDRVGRRRVYGACLLLMVCSSVGSGLSVCRTRRCALASLCFFRFLLGVGVGGDYPLSATIMSEFANRRTRGAFIAAVFSMQGFGILVSSAVTMAVAAAFDHYTGYPAPLDTPECADLAWRIILMAGAVPAALTYYWRMSMPETARYTALVERDVVKATNDIGRVLADLDLAAVAEEEVAAAALSPPPVTTPPPPRPSYGLFSRRFVRQHGRDLFACAAAWFLLDIPYYSSTLFQSQIYRPWFPPAAKVNAFQEAFNVAKFQAVIAVASTIPGYFAAMLLIERAGRRRLQMAGFLLMAVFLFALAGPYDGYWRDHAKTAGYIVLYSLTFFSANLGPNTTTFILPAELFPARFRSTCHGLSGAAGKLGALVGSIGFLWASQQKDGAAAGHLPGIGMMYALFVLGGICLLGLALTYAFTPETMTRSLEENESSVQAQSQVGDGGSDAGNGSDGLRFHELNVLMEAATKSPVSMASSHLSMSPILPHRMSL
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-9, OsPT9, OsPht1;9, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL21_PASMU
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLEVATGETVEFDSVLMIVNGEDVKIGAPVVAGGKVVAEVVAHGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SCTC1_SALTY
Sequence: MKTHILLARVLACAALVLVTPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEAIK
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:9786184, PubMed:27974800, PubMed:30242280).  Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane (PubMed:9786184, PubMed:21385715, PubMed:27974800, PubMed:30242280).
What are the official names of this protein?
SPI-1 type 3 secretion system secretin, T3SS-1 secretin, Protein InvG.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. T3SS SctC subfamily.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Localization to the outer membrane requires InvH/SctG.
Protein: LGT_BURO0
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFIAAIVVGRIRLKLPYVAAQGWTAKDIDDMMFYGVLGTVLGGRLGYVLFYKADFYFSHPLDVFKVWEGGMSFHGGFLGVTLAMMLFAWQRKRHWLQVTDFVAPMVPLGLAAGRLGNFINGELWGRVTDPTAPWAMLFPGAMRDDAAWLPKHPELVEKWHLADVFMQYQMLPRHPSQLYEIALEGIALFFVLFLFARKPRPMGAISALFLIGYGLARFTVEFAREPDDFLGLLALGLSMGQWLSLPMILAGIAMMIWAYRRRAANANAAA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
Protein: RPC1_BPP22
Sequence: MELTSTRKKANAITSSILNRIAIRGQRKVADALGINESQISRWKGDFIPKMGMLLAVLEWGVEDEELAELAKKVAHLLTKEKPQDCGNSFEA
What is the function of this protein?
Binds to two promoters, P(RE) and Pa23 and activate transcription from these promoters.
What are the official names of this protein?
Transcriptional activator protein C1.
What is the protein family that this protein belongs to?
Belongs to the lambda phage CII protein family.
Protein: SUS1_ASHGO
Sequence: MTAKDKEALELRAQIQQHLVESGNYERISNKLAQRLLDEGWIDQVKKLTRETMEDDNTTNFSEVLKRVEPEAVSLVSANTKNEIMQQIKAFLCDILDTQ
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: TPIS_SALTI
Sequence: MRHPLVMGNWKLNGSRHMVNELVANLRKELTGVAGCDVAIAPPEMYIDLAKRAAAGSHIMLGAQNVDLNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDTVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSCF_YEREN
Sequence: MSNFSGFTKGNDIADLDAVAQTLKKPADDANKAVNDSIAALKDTPDNPALLADLQHSINKWSVIYNISSTIVRSMKDLMQGILQKFP
What are the official names of this protein?
Yop proteins translocation protein F.
What is the protein family that this protein belongs to?
Belongs to the MxiH/PrgI/YscF family.
Protein: BETA_VIBVU
Sequence: MQQHYDYIIVGAGSAGCVLADRLSESGDHSVLLLEAGGSDKSIFIQMPTALSYPMNSEKYAWQFETDAEADLDGRRLHCPRGKVLGGSSSINGMVYVRGHACDFDEWEEQGAKGWNYQACLPYFRRAENWIDGEDEYRGGDGPLSTCAGNKMTLNPLYRAFIDAGKEAGYPETSDYNGYQQEGFGPMHMTVKNGVRASTSNAYLSRAKKRSNFKLIKGVVVQRILLEEKRAVGVEFELAGELRTCFAKNEVISSAGSIGSVQLLQLSGIGPKTVLEKAGVTPVHHLPGVGQNLQDHLEVYFQYHCQKPITLNGKLDWFSKGLIGAEWILTRKGLGATNHFESCAFIRSRAGLKWPNIQYHFLPAAMRYDGQAAFDGHGFQVHVGPNKPESRGRVEIVSANPSDKPKIQFNYLSTERDRQDWRDCIRLTREILAQPAMDEFRGEEIQPGINVATDAEIDQWVKENVESAYHPSCSCKMGADDDPMAVLDEECRVRGITNLRVVDSSVFPTIPNGNLNAPTIMVAERAADLILHKQPLPPQRSKVWLAPSWETQQRTGEPMR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: QKIA_XENLA
Sequence: MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFTHLERLLDEEISRVRKDMYNDTMNSSSNEKRTSELPDGIGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAELKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANLKSPALAFSLAATGQAPRIITGPAPVLSPAALRTPTPAGHTLMPLIRQIQTAVMPNGTPHPTATLMQQAPEGGLIYTPYEYPYTLAPATSILEYPIEASGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN
What is the function of this protein?
RNA-binding protein that plays a central role in myelinization.  Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence.  Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation.  Required to protect and promote stability of mRNAs which promotes oligodendrocyte differentiation.  Participates in mRNA transport by regulating the nuclear export of MBP mRNA.  Also involved in regulation of mRNA splicing of some pre-mRNA.  Acts as a translational repressor (By similarity).  Essential for notochord development.
What are the official names of this protein?
KH domain-containing RNA-binding protein qki.S, Protein quaking-A, Xqua.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FABZ_DESVM
Sequence: MTDPAQNILDIRQILGLLPHRYPFLLVDRVTEYVPGEYIKGYKNVTMNEPFFEGHFPGVPVMPGVLIMEALAQAGGILVVKSTDTPVEDKLFLFTGIESVRFRKPVYPGDKLELHCRLLRHKLKLWKMEGFAYVDGKLAAEAVMTAAVTNREDM
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SPHAL
Sequence: MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGEQMSSLEFANLLENWRDGGVREARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAMLAEQLWRATSIIAGHPYHREGRQ
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_RHOPB
Sequence: MSVVESHDIEFAAPRISEASVADYIALLKPRVMSLVIFTALVGLLLAPGYIHPVLAFTSILCIAVGAGASGALNMWYEDDIDAKMTRTANRPIPRGRVSKPEALTFGLVLSFFSVVTLGILVNWFAAALLAFTIFFYVVIYTIWLKRWTAQNIVIGGAAGALPPVVAWAAAAGSLSVEPMLLFAIIFFWTPPHFWALALFRAGDYANAGVPMLPVTAGPDATRLSILLYTIVLVAVAFAPWPLGYFDAIYGITSLALGGWMLLLTLRVYRLRHGSAALRASRSLFKFSILYLFALFAVLLLEVIVRGVIGALA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AGP15_ARATH
Sequence: MAISKASIVVLMMVIISVVASAQSEAPAPSPTSGSSAISASFVSAGVAAVAALVFGSALRI
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Arabinogalactan protein 15, AtAGP15, Arabinogalactan peptide 15, AG-peptide 15.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CTB11_CERBT
Sequence: MHFPALAVAGCLLSRATAQSLDQVLAKRDSFSLLRDLLHQHGLVDELEFTANATFFAMTNQALRSLADFGINLTTADPNIARAIFKYAQLDAIYTTDTVKALHHEAKVVQTALQPHLFNNLTRGQAAKLRSNRTGGANGILVESGLGVLTPVVEADIPYDHGVIHAIDANMVLPHNISETARLGGMTEFLNLLERSDSVARLESLSDVTIFIPQDEALAKLQPILDMLTSEQLKSVVAQHAVPNRVLYQSLFDGVETLETLDGSTLRIRRGKRGEIFVNGAEVVRTDLLLYGGVAHLIDGALLPEKDASCSTGLFAAAAGGSSRVWKILASHQLTLLAVLAMALVSILYKAYQSRKQSHQLIRPSDGLGNYEKV
What is the function of this protein?
Fasciclin-like arabinogalactan protein; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin (PubMed:29844193).  The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules (PubMed:11701851).  These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids (PubMed:11701851).  The first step of cercosporin biosynthesis is performed by the polyketide synthase CTB1 which catalyzes the formation of nor-toralactone (Probable).  The starter unit acyltransferase (SAT) domain of CTB1 initiates polyketide extension by the selective utilization of acetyl-CoA, which is elongated to the heptaketide in the beta-ketoacyl synthase (KS) domain by successive condensations with six malonyl units introduced by the malonyl acyltransferase (MAT) domain.  The product template (PT) domain catalyzes C4-C9 and C2-C11 aldol cyclizations and dehydrations to a trihydroxynaphthalene, which is thought to be delivered to the thioesterase (TE) domain for product release (Probable).  The bifunctional enzyme CTB3 then methylates nor-toralactone to toralactone before conducting an unusual oxidative aromatic ring opening (Probable).  The O-methyltransferase CTB2 further methylates the nascent OH-6 of the CBT3 product, blocking further oxidation at this site before the reductase CTB6 reduces the 2-oxopropyl ketone at position C7, giving naphthalene (Probable).  The FAD-dependent monooxygenase CTB5 in concert with the multicopper oxidase CTB12 are responsible for homodimerization of naphthalene with CTB7 installing the dioxepine moiety, finally producing cercosporin (Probable).  The fasciclin domain-containing protein CTB11 might act with CTB5 and CTB12 whereas the roles of CTB9 and CTB10 have still to be elucidated (By similarity).
What are the official names of this protein?
Fasciclin-like arabinogalactan protein CTB11, Cercosporin toxin biosynthesis cluster protein 11.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.