PharMolix/UniProtQA huggingface dataset:
Protein: ADEC_KLEP7
Sequence: MSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGAEMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAVDALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGIARLRHIRGARFTQWGEVEVQVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: ZEB2_MOUSE
Sequence: MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDAGSETDEEDKLHIAEDDSLANPLDQDTSPASMPNHESSPHMSQGLLPREEEEEELRESVVEHSWHSGEILQASVAGPEEMKEDYDAMGPEATIQTTINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGSSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKTEDISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHSISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGLTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERTSKPLAPNSNPTTKDSLLPRSPVKPMDSITSPSIAELHNSVTSCDPPLRLTKSSHFTNIKAVDKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMREPKGIIATKNKTKATSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSNNPVFGMNPFSAKPLYTPLPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGDLLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEEGYGKLRRRDGDEEEEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGME
What is the function of this protein?
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters.  Represses transcription of E-cadherin.  Represses expression of MEOX2.
What are the official names of this protein?
Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, Zinc finger homeobox protein 1b.
What is the protein family that this protein belongs to?
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TPIS_PECAS
Sequence: MRHPLVMGNWKLNGSTNLVNELIAGLRKELSTVDGCGVAIAPPAIYLDQANHQLAGSRIALGAQNVDVNLSGAFTGETSAEMLKDIGAKYIIIGHSERRTYHKESDEFIAKKFGVLKDAGLIPVLCIGETEAENEAGQTEAVCARQLDAVLNTLGAKAFENTVVAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAVAEQVIIQYGGSVNAANAAELFTQPDIDGALVGGASLKADAFAVIVKAAADAKRG
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_BURO1
Sequence: MAKVLVLYYSSYGHIETMAQHIVEGAKSVPGVEVTLKRVPETIPVDQARAIGVKVDQAAPVATVDELADYDAIIFGTPTRFGNMAGQMRTFLDQTGGLWMKGALVGKIGSVFASTGTQHGGQETTITSFHTTLLHHGMVIVGVPYACSGLVNMSEITGGTPYGATTLAGADGSRQPSANELDIARYQGKHVAELASKLAS
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: YJ12A_YEAST
Sequence: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-JR2 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADC_BURA4
Sequence: MKISDVRSKAFAMPLTSPAFPMGPYRFVDREFLIITYRTDPDRLREIVPEPLQITEPLVHYEFIRMADSTGFGDYTESGQVIPVEYNGQAGGYTLAMYLDDHPPIAGGRELWGFPKKLASPTLHVNTDHILGTLDYGKVRVATGTMGYKHKDLDIEEQAKRLAGPNFLLKIIPHVDGTARVCELVRYYMQDIKMKGAWTGPASLELAPHALAPVADLPVLEIVEARHIVADLTLGLGEVVYDYLAQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: KUP_ACIAD
Sequence: MQSSAKKVALPAMTLAALGVVFGDIGTSPLYAFAQTFTSAHVNISEATVFGILSLIFWCITLSISFKYVSIVMRADNNGEGGIMSLLALLLRIKQLDSNKKIYLIALGFVGASLFFGDGIITPAISVLSAIEGLSIATPAFDRWLIPIGLGILTALFMVQRHGTATMGKFFGPITMLWFISIGALGLYSIIQTPHILWFINPIWAIEFAIHQPFVAFVAMGSVVLTMTGGEALYADMGHFGRMPIRLAWFIVVCPSLMLNYAGQGALLLRDPQAVSNPFYLLVPEWALFPMIGLATAAAVIASQAVITGVFSMVNQAIQLRYLPRLTVIHTSDVEQGQIYVPFINWVLYISVFFLIILFESSSNLASAYGVAVTMTMLCVTILISVLAYGAWGWPWWKVTLFAVPFLALDGIFVASTSLKILSGGWVPFVIGVVVFTILMTWKRGREIVFNRLETDALPISLFIKSIGSSAETHFVPGDAVFLTGNPNIVPHAMLHNIKHNKVLHSRNIMVTVYTEDIPYVAKEQRVQLEKMDEHFYRISMYYGFKDQPNIPQALEQAYQALDLEFDMMQISFFISRDRLIHTVGDGMSPWREKLFISMQRNTSPVSDFYQIPPNRVVEMGSQIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHYS1_METMA
Sequence: MDFGASAKNLSTPVKGAKIVPNMTVDELVKEYAGCAFGAGRLAEAVDIYYEMLASGKTTKFFGLAGAMTPAGMRNIIADLIRDGYIDVLVTTGANMVHDTVEALGLHHYKGSDCANDIQLRHECIDRIYDVYLPDQHFTDLEEFLQGVYSGLPQENLSIRQVLTEIGKNLDDDSSILKTAAEMGVPVYCPALQDSVIGLQAWLYKEGNPLHVDAFADMHEFMDICYGAESAGTMLLGGGVPKNYILQSMLVTPRSFDYAIQLTMDRPETGGLSGATLDEAQSWGKVGEDAKSVTVYADSTITLPLIVSAVRTRLSKR
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase 1, DHS 1.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: MINE_PSE14
Sequence: MNIFDFFRDRKKESTASVAKERLQIIVAHERGQRSTPDYLPALQKELVEVIRKYVNIESDQVQVALESQGSCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: YHI2_MYCTO
Sequence: MPCVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLTDTPPEALADMVAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLHVLPPRNGDKLSVAKGMMLRRDPDREATGRILREALAQQDAAAQD
What are the official names of this protein?
Uncharacterized HIT-like protein MT1300.
Protein: SECM_ECOLU
Sequence: MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLS
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: TBB5_CHICK
Sequence: MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYVPRAVLVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQNKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQEATANDGEEAFEDDEEEINE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-5 chain, Beta-tubulin class-V.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KDSB_AFIC5
Sequence: MTEHDTLVLIPARMAASRLPGKPLLDIAGLPMIAQVLRRAREARLGRVAVATDSAEIAAAVAAEGGEAVMTSADHPSGSDRIFEALEKLDGEGRIKTVINVQGDLPTIAPADIRAVLQPFAEPTVDIATLAAQIRVAAEHDNPNVVKVVGSPLSQDTLRALYFTRCTAPFGEGPRYHHIGLYAYRRTALARFVALPPSSLERREKLEQLRALEAGMRIDVRIVDSVPLGVDTPDDLEAARRILAKQA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_PROM0
Sequence: MIKTSWEGNCFLNFFNNKASLGNVDKTIFKSKSTSPYKLLKSTHDQEGRCILPVLHTAGGLVGGDSLEFEVNLEKNSKVLLTTSSAQKVYGSVGISKINPKGTFSKQKNLIKILDNSHLEYLPQETIIFANGLYEQKFKVSISETSSFLFTDLIRLGRSSSGESIESGVFRSKLEIMRNNDLYDDWEYVDQIELSKESYAAKSGMDYMPVFGSLIWVCEKDFSASKINNLVGNIKKIFNETDNNLSIGILENGISVRFLGSSSQEARKCFFCIWKQIRSVSGFCEPKYQGVWPLQDSMNY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP85_BOVIN
Sequence: MEEFDGEPTVTWIPGVNSQKKQMCFDWGPGEMLVCETSFNKKEKSEMVAGCPFIHIIRKDIDVYSKILRKLFNESHGIFVGLQRIEEELTGKSRKAQLVRVSKNYRSVIRACMEEMHQFAVADKDSAIGRQFSSQVSILSAVELIWNLCEILFIEVAPAGPLLLYLLDWVRLHVCEVDSLSADVLGSENPSKHESFWNLVTTLVLQGRLDEARQMLSKEADSNPTSAGMCRVLGDLMRTMPILSPGNTQTLTELELRWQHWHEECERHLQDGTFASNPHLESLCKVLLGDDAALLEHKELLSNWYHFLVTRLLYSQPTVKPMDLHLYAQSSLDLFLGGESSPEPLDNILMAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYCDHCPELGRVSLELHIERIPLTTEQKALKVLRVCEQRQMTEQVRSICKVLAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKCFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELLRCLEDLTSGRPLCGEPDAQQLQDDDIETTKVEILRLALARNLARSIIKEGSLEGS
What is the function of this protein?
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance.  As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus.  The Nup107-160 complex seems to be required for spindle assembly during mitosis.  NUP85 is required for membrane clustering of CCL2-activated CCR2.  Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.  Involved in nephrogenesis.
What are the official names of this protein?
Nuclear pore complex protein Nup85, 85 kDa nucleoporin, Nucleoporin Nup85.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup85 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane. Note=During mitosis, localizes to the kinetochores and spindle poles. Upon CCl2 stimulation translocates from the cytoplasm to the membrane and colocalizes with CCR2 at the front of migrating cells.
Protein: IUCC_VIBMI
Sequence: MVMDQLALHRYWAVANQKMVGKILSEFAYEQAFQFEPTAQGYQLNLENGTRYCFAGEENIWGQVMIDPTSITRHAEIEADEPISAALLMRDLQPLLKMPDDAFAEHLEDLNATLLGDCKLMQRNEAITARDLAMLPCEQQQTYFDGHPKFVFNKGRRGWGSDDLKRYAPEAERVSNWVGSRFITRFCSSPPTMKSHGKPCCKAPSRPMKSSRWTVCWLPISLDSTIIVMFRFILWQWSNKLALLFVREIATKQLVYLGEFGDHFLPQLSLRTLSNVTRPAGYDIKLPLTVMNTSCYRGIPGRYILAGPTASDWIDQVFKSDPLLIAKQAEVLQEPAAAFAAQADYALLPNAPYRYHELLGVIWRESAASKLKAGERAILMAALMESDNQGQPLIAEYVQASGLTLEAWLSKLFDAVVIPYYHLLCNYGVSLIAHGQNVTLVLENHAPKRILLKDFQGDMRLVSREYPEQASLDDSVKKVTVRLPEHLIIHDLQTGHFVTTLRFISPLVAKLGFSEPQFYRLLGDRLKAYMAAHREYQPRFEQFDLFKPRILRIGLNLAKFRHSTDASASRMLPDMDDMLNNPLTKALEHQG
What is the function of this protein?
Catalyzes the attachment of the second N-acetyl-N-hydroxylysine to the carboxylic group of N-citryl-N-acetyl-N-hydroxylysine to yield aerobactin.  Involved in the biosynthesis of the siderophore aerobactin which is a chelator that mediates the high-affinity iron transport systems induced under iron-stressed conditions.
What are the official names of this protein?
Aerobactin synthase.
What is the protein family that this protein belongs to?
Belongs to the IucA/IucC family.
Protein: HNT2_YEAS8
Sequence: MNKPIYFSKFLVTEQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINNVGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL
What is the function of this protein?
Cleaves A-5'-PPP-5'A to yield AMP and ADP.  Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine.  Is most effective on dinucleoside triphosphates.  Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Hit family protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: PTC_LISMO
Sequence: MNKKRDFIDTKDFSKEEILFMIEIGRKMKESIKNGHYPQLLKHKTLGMIFEQSSTRTRVSFETAMTQLGGHAQYLAPGQIQLGGHESVGDTAKVLSRLVDILMARVERHQTVVELANTAAIPVINGMSDYNHPTQELGDAITMFEHLPKGKKIEDCKIVFVGDATQVCASTMFMATKLGMDFVQFGPKGFQLREEHLKVAEENCEVSGGSYLITEDVDIALKDADFIYTDVWYGLYEAELSEEERMKTFYPKYQVNKELISKAAPHVKFMHCLPATRGEEVTDEVLDAPYSVVIDEAENRLTAMRALLVYFMNPYVKEAGFAVAEKYDAELELLLRNGAGL
What is the function of this protein?
Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine.  Is involved in the degradation pathway of the polyamine agmatine.
What are the official names of this protein?
Putrescine carbamoyltransferase, PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_ANADE
Sequence: MITGRTALYGVVGHPVAHSRSPEMQNAAFAKLGVDAAYVALPVAPERIDEALRGAHALGFQGLNVTVPHKPRAASLCHALDPVATAVGAANTLRRTRDGWEGFNTDAPACRTLLEAAGVARGARALLVGAGGAARAAAWALLQLGTELRVAARREEAAAELCRDLAAAVPGADAATADFEDLEAEADAAAVVVNGTSVELPGHEGRLPPLRFRADQVVLDFVYGDTELARAARAGGARLVTGEQVLVRQGALAFTIWTGLPAPEADMARALEAREGAR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: TSGA_BUCAT
Sequence: MTNINRIGLTWISFLSYAFTGALVVVTGMIMGNISNYFHLSISQMSNIFTFLNAGILVSIFINSWLIEIISLKKQLIFSFILTIIAVIGIVLCNSIFLFSINMFILGLVSGITMSIGTFIITHLYSGSKRGSLLLLTDSFFSMSGMIFPIVTAYLLEKKIIWYWSYICIGAIYLLIFLLTINSSFEKFKTNTKNSKETKEKWNFNVFLLSISALLYILGQLGFISWVPQYATEIMNIDIKKTGSLVSGFWMSYMLGMWFFSFIIKFFNLYRMFIFLTSMSTILMYCFIKSENFLNQQYIIISLGFFSSAIYTIIITLASLQTKHPSPKLINLILLFGTIGTFLTFIITSPIVEAKGLYVTLISSNILYGIVFFLSILIYFNKKYEGVI
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERB1_COPC7
Sequence: MALTDSKKKATSKRKRDEPEQEQTHTLTSQLEMLTDEEGDDDNAGDVSDDGEYDEFPEIDAESDSEEEDEEEDEEDEEDEPDISDEEDSDSDESLHVFPKAKTVVSDITGQQKRVYPEIEPDYDSDSSTEDSPNRVGNVPMHWYDDLPHIGYDINGKRVLRPAKGDELDKFLATIEDPDSWTSAFDKKMQMDKPLTSEELDIIQRLYAGENPDATYDPYEPMVEWFTGKGKEEIMPLSAAPEPKRRWVRSKWEKQKIMKIVRAIRQGRIVPNKPKTSSKQFEFYSIWSSEPSSSQPPPLPAPKRPLPTNAESYNPPEEYLPTEEEKQEWLKQDPEDRERDFLPQKFSSLRHVPAYDQFIKERFNRQLDLYLAPRIQRVKLNIDPNSLIPKLPSPSSLKPFPNYRSLLFTHPKGRARCVSVSPDGAWAVSGDEDGVVSLWEVNVGCEIRRWKFEGKIGSLEWCPRADACYFAVGIEETIHFLIPPNLDPTVLALTQTLLAPSTLPPAPATPSAVKWSSSSLSSWSVEQPILSLNLPPSSGLPTQISWHKKGDYIATVSSGGAQNGVWIHQFTRRHSQAPFKKIKGAVQQVLFHPIKPHFFVATQQYVRLYNLAEQKLIKTLQPGIRWISSMDVHPSGDHVIVGGYDRKLCWFDLELSEKPYKVLRYHSRAIRSLHFHPTYPLFASSSDDGSIQIFHARVYNDLMTDPLIVPLKILRGHQITDGLGILQVKWTPKHPWLLSAAADGTVAVWCS
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CFDP2_BOVIN
Sequence: MEEFDSKDISTSKDEDCVPLGGECHEDDINELVKEDEVDGEEETQKTKGTKRKAESILARKRKQGRLSLDQEEEEDASRESGGRIIEKEDAAAEQEKGAESEDARQEEADVLASSVSDAEPKSELPPSTQTKTGEETEETSSSNLVKVEELEKPKKAEEVKLTKSPLAGEEVRFLTQQGRLSGRTSEDEPRRSEGVQHATGEERRADTNTSSKNEAAGQKWKGQSAVDVSGDESKLRCCKEEYCIGTWNVRSMNPGKLDVVKQEMERINIDILGISELKWTGMGELNSDDHYIYYCGQQSLRRNGVALIVNKRVRNAIIGCNLKNDRMISVRFQGKPFNLTVIQVYAPTPYAEEGEVYRFYEDLQHLLEITPKIDVLFIIGDWNAKVGSQEIPGITGRFGLGMQNEAGRRLIEFCHHNRLVITNTLFQQPSRRLYTWTSPDGRYRDQIDYIICRQRWRSSVQSAKTRPGADCGSDHKLLIAKFRLKLKIIPKTTRPFRVTNEEDATNEEAKSVLKQNEKEKPEANVPSTVSSVPGGSGMTKEVGETSQEAKSVFKQDEKDKPQANVPSSVPSLPAGSGPEKCDLEKKKDCNN
What are the official names of this protein?
Craniofacial development protein 2, p97 bucentaur protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ERH_MOUSE
Sequence: MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK
What is the function of this protein?
May have a role in the cell cycle.
What are the official names of this protein?
Enhancer of rudimentary homolog, Mer.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_SHESA
Sequence: MNPIDTDDLEKHTPMMRQYLTMKAEHHDMLLFYRMGDFYELFYDDAKRASELLGISLTARGKSGGDPIPMAGIPYHAVEGYLAKLVQIGQSVAICEQIGDPATSKGPVERKVVRIVTPGTLTDEALLQERQDNLLAAVYQGKVGFGYATLDVSSGRFVIAELETKESLEAELQRTNPVEILYSEDFGAMELLHHFKGKRRRPEWEFDYDTSIKLLLAQFGTKDLHGFGITDARLSLQAAGCLMQYVKDTQRTALPHINAITRFNQTDTIVLDAATRRNLELTQNLSGGRDNTLAAVLDNTATAMGSRMLQRWIHQPLRDHAQIFARQTAVNELLETTAHESLHDQLKALGDIERIMARLALRTARPRDFARLRQALNLLPQLQQSLAQLSAPHTVKLGQLLGEFPEEQQLLERAIVDNPPMLIRDGGVIREGYNAELDEWRGLSEGATDYLVQLEAREKERTGIATLKVGYNRVHGYYIEVSRLQSQQVPLNYQRRQTLKNMERYITPELKEYEEKVLSSQGKALALEKQLWDELFDLILPKLHELQAFARAAAELDVLSNFAERAETLGYTCPELSSEIGVKIEAGRHPVVERVSQTPFIANPVTLHNQRRMLIVTGPNMGGKSTYMRQVALITLMAHIGCFVPADRAIIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATAQSLVLMDEIGRGTSTYDGLSLAWSAAEYLAQQVGAMTLFATHYFELTQLPELMAGVYNVHLDAIEHEDTIAFMHAVQEGAASKSYGLQVAALAGVPARVIKAAKHKLHQLESRDHQVEGANVNGTRAPIQTLLALPEPVENPAVSKLKDINPDNLTPKQALDLLYELKRLS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HYAL3_RAT
Sequence: MITQLGLTLVVGLTLCLVHVQALLQVPEFPFSVLWNVPSARCKTRFGVHLPLDALGIIANHGQRFHGQNITIFYKNQFGLYPYFGPRGTAHNGGIPQAVSLDHHLAQAAHQILHNLGSSFAGLAVLDWEEWYPLWAGNWGTHRQVYQAASWAWAQQMFPDLNPQEQLHKAQTGFEQAARALMEHTLRLGQMLRPHGLWGFYRYPVCGNGWHNMASNYTGHCHPAIITRNTQLRWLWAASSALFPSIYLPPRLPPAYHQTFVRHRLEEAFRVALTGHAHPLPVLAYVRLTHRSSGRFLSLDDLMQTIGVSAALGAAGVVLWGDLSVSSSEEECWRLHDYLVGTLGPYVINVTKAATACSHQRCHGHGRCSWKDPGQMEAFLHLQPDDNLGAWKSFRCRCYLGWSGPTCLEPKP
What is the function of this protein?
Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid.  Involved in induction of the acrosome reaction in the sperm.  Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate.  Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage.  Has no hyaluronidase activity in embryonic fibroblasts in vitro.  Has no hyaluronidase activity in granulosa cells in vitro.
What are the official names of this protein?
Hyaluronidase-3, Hyal-3, Hyaluronoglucosaminidase-3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Cytoplasmic vesicle, secretory vesicle, acrosome. Endoplasmic reticulum. Early endosome. Note=Mostly present in low-density vesicles. Low levels in higher density vesicles of late endosomes and lysosomes. Localized in punctate cytoplasmic vesicles and in perinuclear structures, but does not colocalize with LAMP1. Localized on the plasma membrane over the acrosome and on the surface of the midpiece of the sperm tail.
Protein: RDGC_KLEP3
Sequence: MLWFKNLMVYRLSRDIELRAEEMEKQLAELTFTPCGSQDMAKTGWVSPMGSHSDALTHTANGQIIICARKEEKILPSPVIKQALEAKIQKLEADQGRKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKTLGSLPVVPLTLENPIELTLTEWVRSGTVAQGFQLLDEAELKAMLEDGGVIRAKKQDLVSDEIAVHIEAGKVVTKLALDWQQRIQFVICDDASIKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQSLVEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.