PharMolix/UniProtQA huggingface dataset:
Protein: STT3B_MOUSE
Sequence: MAEPSAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGTQSASSAAAPKPGPPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRENPPVEDSSDEDDKRNPGNLYDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIREGDYFTQQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNRETLGHKPRVTNIVPKQKYLSKKTTKRKRGYVKNKLVFKKGKKTSKKTV
What is the function of this protein?
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets (By similarity).  STT3B is present in a small subset of OST complexes and mediates both cotranslational and post-translational N-glycosylation of target proteins: STT3B-containing complexes are required for efficient post-translational glycosylation and while they are less competent than STT3A-containing complexes for cotranslational glycosylation, they have the ability to mediate glycosylation of some nascent sites that are not accessible for STT3A.  STT3B-containing complexes also act post-translationally and mediate modification of skipped glycosylation sites in unfolded proteins.  Plays a role in ER-associated degradation (ERAD) pathway that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins by mediating N-glycosylation of unfolded proteins, which are then recognized by the ERAD pathway and targeted for degradation (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B, Oligosaccharyl transferase subunit STT3B, STT3-B, B6dom1 antigen, Source of immunodominant MHC-associated peptides.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: BIP1_ORYSJ
Sequence: MDRVRGCAFLLGVLLAGSLFAFSVAKEETKKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAAVNPERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDGKPYIQVKIKDGENKVFSPEEVSAMILGKMKETAEAYLGKKINDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLIKKKYSKDISKDNRALGKLRREAERAKRALSNQHQVRVEIESLFDGTDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLEKSQIHEIVLVGGSTRIPKVQQLLRDYFEGKEPNKGVNPDEAVAYGAAVQGSILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSMTKDCRLLGKFDLSGIPAAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNEKGRLSQEEIDRMVREAEEFAEEDKKVKERIDARNQLETYVYNMKNTVGDKDKLADKLESEEKEKVEEALKEALEWLDENQTAEKEEYEEKLKEVEAVCNPIISAVYQRTGGAPGGGADGEGGVDDEHDEL
What is the function of this protein?
Key chaperone involved in folding of secretory proteins in the endoplasmic reticulum (ER) lumen (Probable).  Involved in ER quality control for seed storage proteins during seed maturation (PubMed:19567376, PubMed:21223397).  Functions as a sensor of the ER stress response, and provides suitable conditions for the production of secretory proteins by alleviating ER stress (PubMed:19567376, PubMed:21223397).
What are the official names of this protein?
Heat shock 70 kDa protein BIP1, Luminal-binding protein 1, OsBiP1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Localizes close to the endoplasmic reticulum (ER) membrane complex of developing endosperm cells. Localizes to the periphery of the prolamine protein bodies which originate directly from the ER.
Protein: LCB2D_ORYSJ
Sequence: MVRLPYVTALTTLFSYGLLFAFGQLRDFFRRILDAGKSSNLKGYAPICLGLEDFYTRRLYLRIQDCFGRPIASAPDAWFDVVERYSNDSNKTLHRTTKTSKCLNLGSYNYLGFAAADEYCTPRVIESLKKYSASTCSVRVDGGNTKLHVELEELVARFVGKPAAILFGMGYVTNSAIIPALVGKGGLIISDSLNHNSIVNGARGSGATVRVFQHNNPAHLEEVLREQIAGGQPRTHRPWKKIIVIVEGIYSMEGELCKLPEVIAVCKKYKAYTYLDEAHSIGAVGKTGRGVCELLGVDPADVDIMMGTFTKSFGSCGGYIAASKEIIDHLKHICPAHIYATSMSPPAVQQVISAIKVILGEDGSNRGAKKLAQIRENSNFFRSELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRQHVAVVTVAFPATPLLLARARICISASHSREDLIKGLEVISKVGDLVGIKYFPVEHEKTASVEKLKKLQ
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB1 constitutes the catalytic core (By similarity).
What are the official names of this protein?
Long chain base biosynthesis protein 2d.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: THIM_KLEP7
Sequence: MPELLNPAPVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGMSAGGRGVDTTDTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGAIAARQGGPGSFIPAFLDALYQEVQG
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: FTSH3_PETMO
Sequence: MQNKRNQSRVLWLLLIYITIGIFIYVGVNSLIGTPDVSKIEYSELVQMLEDKKIVSLEIEDSGYARARDNRGLYYETYAPTLLSDQQYVYGLANQGIEIKYVRSLENSWWISILTFLLPVFLLIFLFTFLFRSSGGGANQGMNFIKSPAKKYDPKKTRTTFNDVAGVKEAKEELTDVVKFLKDPKVFNRLGARMPKGVLLVGEPGTGKTLLARAVAGEAGVPFFYISGSDFVELFVGVGAARVRDLFNQAKANAPAIIFIDEIDAVGRQRGSGLGGGHDEREQTLNSILVEMDGFDPSIGIIVMAATNRPDVLDKALLRPGRFDKKVVIDRPDAEGRKDILKIHFRGKKIAPDVDLEVLARATPGFVGADLENLVNEAALLAARNGEKFITMKDCEEAIERVIVGPERKTRVLSEQEKEVVAYHELGHAILGTILPNADPVHKVTIIPRGYAALGYTLQLPSEDRYLMNKSEILDDIAVMLAGRAAEEIIFDEITSGAENDLKRATEMARRMVESFGMSEKIGPVAWASESEETFLARELFREKNYSDETAKELDSEVKQIINKSYEKAKSVLLENKEKLQFIAQYLLKKETISGQELRDLLQKDTDDLKEYVENLGVSSTQEEAKVVNYEYLSRENNLIERKGI
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: SYGB_THEP1
Sequence: MRTALLEVGLEELPASEFHSILKQLEERSTELLKAYRISSGSAEVFVGSRRFGVILKNLPERQEDFTEEKKGPPLNVAYDENGKPTKALEGFLRNNNASLENVVHREGYIYLSRVVEGKPVEEVLPDLFRDLVLGLNFRKPMRWGSGEHEYIRPVHWIVAMVDGRVLDLEIFGLRSSRISYGKRYHAGSIKIPDPERYYESLKKGFVISSHLERKKFVLEQIDEFEKRSGMKIERDEELIEEIVAITEYPRIVVGQFDRKYLELPEEIIVTAVKHHQRSFIAHKETLTNTFVAFQDGPQPPENVVKGYERVINARLEDARYYFQKDLETPLEKMNEKLKEIVFQEKLGTLYDKVERIKKISERLCEDLKLPESFTQKVLEAASICKADIASKVVYEFPELQGVMGRIYALREGINEEIATAIEDHYSEEPQTVIGSILGIADRIDTIVGNFAIGNVPTSSKDPYGLKNKADAIFRIIRKNEWDISLEELLTFASSLVGYRLSEELETFFAGRFYQFLVNELGISFDVARAVNHLWKRPLRGILSAEALQEISEKPEFQDLFVGFERVHNITKNHDSVRFDGALFEKEEEKKLMNKFYEVKEKVLKALERLNYREALQYLIELKPYIDEYFDNVFVMVKRDDLRVNRLGFLKNIDELFMMVGDMTYLVKRSQV
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBL60_ARATH
Sequence: MDRVSNLPEEVRCHILSFLPTKHAALTSVLSKSWLNLWKFETNLDIDDSDFLHPEEGKAERDEIRQSFVEFVDGVLALQGDSPIEKFSLKCITGIHPDHVNRWICNVLQRGVSDLYLFTDFSDEDTEEDGGYRLPQEMFVSRTLVKLKLRSEHCVNWWHWDIGASLPNLKSLNIDSDLIFFGEMEKFLSSFPVLEEVHMANMEWRELDETMSSASLTKLSIHGTGVEEFEHPKSISIDTPNLLYLNYSDLVAEDYPLDDEGDVVLQFCNVVKLINGIQNIQTLYLTEDTLEVLTMCCESMPVFNNLKTLGLKSDEGRGWQAVPALLRNCPHLEFLIIEGLLHSVTDKCGDACDCISREDKGRSLISCPVKKLEVRGFRGTIREKEMIRHFLEYFPCLDEMEIDAEENDSTNFEVPRILKVVAYRLHDVVSTEIVGHWQSSAQSGGWSQTQMDEMYYELAPRNKERIYDMFFFMRRASSTVPPPPPQEMSQDYLQMQLEVADLKERQRDQEAKLADLKERLRAMLDMIVDQNPIIASALRAREATNSEREKASSGQEMTEKERDYDALFDIIVEQNPMLASAVRALRATDSERAETSSNQEMTELGQATATYFPPREGE
What are the official names of this protein?
F-box/LRR-repeat protein At3g58940.
Protein: LEP4_PSEAE
Sequence: MPLLDYLASHPLAFVLCTILLGLLVGSFLNVVVHRLPKMMERNWKAEAREALGLEPEPKQATYNLVLPNSACPRCGHEIRPWENIPLVSYLALGGKCSSCKAAIGKRYPLVELATALLSGYVAWHFGFTWQAGAMLLLTWGLLAMSLIDADHQLLPDVLVLPLLWLGLIANHFGLFASLDDALFGAVFGYLSLWSVFWLFKLVTGKEGMGYGDFKLLAMLGAWGGWQILPLTILLSSLVGAILGVIMLRLRNAESGTPIPFGPYLAIAGWIALLWGDQITRTYLQFAGFK
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine (PubMed:8096341, PubMed:8340405, PubMed:23255525).  Substrates include proteins required for pilus biogenesis PilE, PilV, PilW, and PilX as well as some components of the type II general secretory apparatus GspG, GspH, GspI and GspJ (PubMed:8331069).
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase, Protein PilD, Protein secretion protein XCPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX2_APIFL
Sequence: MSTWMMFMFQESNSLYADNLVSFHNMVMIIVIMISTLTVYIIFDLFLNKFSNLYLLKNHNIEIIWMIVPIVILLIICFPSLKILYLIDEIVNPFFSIKSIGHQWYWSYEYPEFNNIEFYSYMLNYSDLNQFRLLETDNRMIIPMKIPLRLITTSTDVIHSWTVPSLGIKVDAVPGRINQLNLISKRPGIFFGQCSEICGMNHSFMPIMVESTSFKYFMNWIYKMN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNLI_RHOJR
Sequence: MLFSQIVATSRDVGATRSRKVKVGALREVLIQLEPAEVEPVVAWLSGELRQGRIGIGWRTLGDIPATPADVPAVTVSDLDGTVTAVAGISGSGSAARRRKLLADLFARTTADERDFLLRLLTGDLRQGALEGVMTDAIAAAADLPVEPVRRAFMLSGRLPATAVAAFDGGVDALTAFRLEVGRPVRPMLASPAESLTDAWTELGGDVSVEYKLDGARIQVHRNGDDVHVFTRTLREITGSVPELVELVAGLPCTSAVFDGETLALTDSGRPRPFQETMSRFGAESARDLLLHPYFFDCLHLDGVDLLDAPLEERLAALERVAPQHRIPGLIRPDSDGAATHFDDALAAGHEGVMVKSLAAPYAAGRRGRAWQKVKPEHTLDLVVLGAEWGYGRRTGYLSNLHLGARDPDGGEPIMVGKTFKGLTDALLQWQTDEFPRHERDRDDHTVYLHPDLVVEIELDGVQVSTRYPGGLALRFARVLRYRPDKTAAEADTIDAVRALLPG
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: CMBL_HUMAN
Sequence: MANEAYPCPCDIGHRLEYGGLGREVQVEHIKAYVTKSPVDAGKAVIVIQDIFGWQLPNTRYIADMISGNGYTTIVPDFFVGQEPWDPSGDWSIFPEWLKTRNAQKIDREISAILKYLKQQCHAQKIGIVGFCWGGTAVHHLMMKYSEFRAGVSVYGIVKDSEDIYNLKNPTLFIFAENDVVIPLKDVSLLTQKLKEHCKVEYQIKTFSGQTHGFVHRKREDCSPADKPYIDEARRNLIEWLNKYM
What is the function of this protein?
Cysteine hydrolase.  Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine.  May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
What are the official names of this protein?
Carboxymethylenebutenolidase homolog.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FMT_HISS2
Sequence: MKPLNIIFAGTPDFAAQHLQALLQSQHNVLAVYTQPDKPAGRGQTLRASAVKILAEKHHIPVYQPKSLRKVEVQEHLSKLNADVMVVVAYGLILPLAVLQTFPLGCLNVHGSLLPRWRGAAPIQRAIWAGDKKTGVTIMQMNEGLDTGDMLHKVCCDITPTETSTSLYTKLANIAPKALLEVLDGLEQGLFKAEVQDESLSNYAEKLSKEEAKLDWSLSAEQLERCIRAFNPWPMSYFVTQDSQGTLQTLKVYQASVLPHQNKPCGTILAADKRGIQVATANGVLNLEQLQPAGKKPMSARDLLNSRADWFKIGQVL
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: VILB_DICDI
Sequence: MEPPLELPTQRKRVIPSKFGILKRNAEIEAEKNRENLQQSSCFSHINEIGKEIGLEIWKIIDDSTIQKVPKVNHSTFETNKSYLLLMGQFYDGNMNIKTYNIHFWIGELLINSQETINFCNDRIEELERIIKYNQKQFDSEQFYPEPILYREFQGKEGDIFMSYFKSYGGPRYVAPLKLTSASAAIATAAKQYKLFHLKGRRNIRVKQVDISSKSLNSGDVFVLDCEDFIYQWNGSESSRLEKGKGLDLTIRLRDEKSAKAKIIVMDENDTDKDHPEFWKRLGGCKDDVQKAEQGGDDFAYEKKSVEQIKLYQVENLNYEVHLHLIDPIGDVYSTTQLNAEFCYILDCETELYVWLGKASANDQRTVAMANAMDLLHEDNRPSWTPIIKMTQGSENTLFKDKFKKGSWGEYVNDNFEKKPITGKGVAAKAVQEKINVDALHNPEKYQLSKEERKSTIPTLHHVDDKHRGELKIWHVRNRNKFEISQSEFGLFYNQSCYLVLFTLFAADGSNNSILYYWQGRFSSSEDKGAAALLAKDVGKELHRSCIHVRTVQNKEPNHFLEHFQGRMVVFKGSRPNATTEVSLENLSSSLQGLYHVRGTEPINIHSIQVEKAISSLDSNDSFILVNFKNTISYIWVGKYSDEKEAALQISSNVFTGYNFQLIDEGDETSEFWESLETNSSLSLLKDYYTQLRTVEQEKKTRLFQCSNNSGVFKVFEIHDFSQDDLDSDDVMILDNQKQIFVWVGKESSDTEKLMANETALEYIMNAPTHRRDDPIFTIQDGFEPHEFTFNFHAWQVNKTQQDSYKSKLSAILGSNNSGPASPIMLPTSGVTLKPTTAATPKPITTPTVTTPKPITTPTVATLKTVTPAVTLKPTTVTTPSKVATTTNTSTPSPTTITTFYPLSVLKQKTNLPNDIDKSCLHLYLSDEEFLSTFKMTKEIFQKTPAWKTKQLRVDNGLF
What is the function of this protein?
Caps actin filaments but displays neither severing nor cross-linking nor nucleating activities.  Protovillin seems to be a villin precursor with only archaic capping activity.  It lacks essential changes in the sequence to allow bundling of actin filaments and consequently the appearance of microvilli.
What are the official names of this protein?
Protovillin, 100 kDa actin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SCTC_PSESY
Sequence: MRKALMWLPLLLIGLSPATWAVTPEAWKHTAYAYDARQTELATALADFAKEFGMALDMPPIPGVLDDRIRAQSPEEFLDRLGQEYHFQWFVYNDTLYVSPSSEHTSARIEVSSDAVDDLQTALTDVGLLDKRFGWGVLPNEGVVLVRGPAKYVELVRDYSKKVEAPEKGDKQDVIVFPLKYASAADRTIRYRDQQLVVAGVASILQDLLDTRSHGGSINGMDLLGRGGRGNGLAGGGSPDTPSLPMSSSGLDTNALEQGLDQVLHYGGGGTKSSGKSRSGGRANIRVTADVRNNAVLIYDLPSRKAMYEKLIKELDVSRNLIEIDAVILDIDRNELAELSSRWNFNAGSVNGGANMFDAGTSSTLFIQNAGKFAAELHALEGNGSASVIGNPSILTLENQPAVIDFSRTEYLTATSERVANIEPITAGTSLQVTPRSLDHDGKPQVQLIVDIEDGQIDISDINDTQPSVRKGNVSTQAVIAEHGSLVIGGFHGLEANDKVHKVPLLGDIPYIGKLLFQSRSRELSQRERLFILTPRLIGDQVNPARYVQNGNPHDVDDQMKRIKERRDGGELPTRGDIQKVFTQMVDGAAPEGMHDGETLPFETDSLCDPGQGLSLDGQRSQWYARKDWGVAVVVARNNTDKPVRIDESRCGGRWVIGVAAWPHAWLQPGEESEVYIAVRQPQISKMAKESRPSLLRGAKP
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells.  Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane (By similarity).  Involved in the secretion of a proteinaceous elicitor of the hypersensitivity response in plants (PubMed:1400238).
What are the official names of this protein?
Type 3 secretion system secretin, T3SS secretin, Hypersensitivity response secretion protein HrpH.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. T3SS SctC subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PRIS_METHJ
Sequence: MRPATRIFIKQRFTDYYDKARISPPSSVKEREFGFIFFDDRYPDDIRMRRHIGFSSGDEMQEYVKSLVPAHAYYSTAYYRTPQAPTMGDKEWLGADLIFDLDADHIMRGSYEAMLERIKGEAEKLLDVLDNELGIDMRTIKLVFSGGRGYHVHVQELAFRDFEPAERRELVDYVCGTGISPSLLLHDWKPGRRGWHDRFRLVLTRYLQDLSTRPIKEVKAELSSLRGVGQVMAERFAGMIPELITLLNTNPSSILLRDQTVRTVFGALTSERESTLLPHIREAAVQADEPVTTDTRRLIRLPGSLHAKSGFKVVPMEVKELHDFDPLIDAVAFGEREVIIESEREYSFSLLGSSYDIPKGRLKVPEAVGVFLCCRGMAEIGGVLDHAS
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: YIDD_BORPA
Sequence: MIRRLLIAPIRFYRYFLSPWVGRQCRFTPTCSAYAIEAIERHGAWRGLWLAARRIGRCHPWSPGGYDPVPPGHGAGAQACCAHRHRTEPD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDC_DROME
Sequence: MAAEEGKFDNILLAVAEKHHGGVPEFLGTLASFLRRKTDFFTGAKQTEWEKLLLDVFNKESKLAVTENYEKIKAREASQRLKAEKERAERKARKQEIDDNKICDITDEEAAAIIKEEETKKRQQLLDSAGGEPSASNRDGISKPIEKVDDESDKSELGKLMPNAGNGCTLENYTWTQTLEEVELKIPFNLTFGLRARDLVISIGKKSLKVGIKGQTPIIDGELCGEVKTEESVWVLQDSKTVMITLDKINKMNWWSRLVTTDPEISTRKINPESSKLSDLDGETRSMVEKMMYDQRQKELGLPTSEDRKKQDILEKFKQQHPEMDFSKCKFN
What is the function of this protein?
Chaperone protein with functions in nuclear localization and cytoplasmic mRNA trafficking (PubMed:9376324, PubMed:26490864, PubMed:33602059).  In postmitotic neurons, acts with nudE downstream of dar1 to ensure correct positioning of the nuclei in primary dendrites and as a consequence, is required for determining multipolar neuron morphology (PubMed:26490864).  Stabilizes PCID2 in the cytoplasm and thereby is required for promoting cytoplasmic mRNA trafficking (PubMed:33602059).
What are the official names of this protein?
Nuclear migration protein nudC, Nuclear distribution protein C homolog.
What is the protein family that this protein belongs to?
Belongs to the nudC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y575_ACTSZ
Sequence: MLAIISPAKTLDYQSAVPKLAVTQPLLTDYSQQLIDVCRQLTPAEIGSLMSVSDKLAGLNAARFADWQKEHNEQNARAAIYAFRGDVYTGLDADSLTAEDIQFAQSHLRMLSGLYGLLRPLDLMQPYRLEMSTKLATAKGKDLYQFWGEIITESLQNALDEQGDDVLINLASDEYYKVVKPSKLQARIVKPVFLDHKNGKYKVISFYAKKARGLMSRYLITQRINRIEQLKHFNLGGYQFDDSVSTEREWVFKRDISE
What are the official names of this protein?
UPF0246 protein Asuc_0575.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SYH_RICAH
Sequence: MTEKLQPLRGIKDLLPDDYKVHDYIISKARDVGVLYGYKQMSTPILEYTKVFNRSMGESSDVISKEIYSFLDKSNESVALRPEFTAGIIRSFISNGLQHKLPLKLFSTGPVFRYDRPQAGRQRQFHQLNYEYIGAKGAITDAETLKLAIDILKALAIEQDTLLELNSLGCSESRSAYKQKLVEYLSDFKDQLSEESKIRMIKNPMRILDSKSEIDQKIVAYAPILSEYYTDESKEYFDELIKYLDILGVKYSINPRLVRGLDYYCHTAFEFTTNKLGSQSTILAGGRYDGLSRIMGNNDDVPAIGFAAGIERIALMREYDISEVKPVFVLPIGDNNITYALEIVDKLRAQNIATIVEPLGKIAKRMQRVLNENAKFIIFIGDEEQENNSIKLKDLEKQEEYIVDFAKAFELLKKY
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_MYCMS
Sequence: MSVNDLRPGTTFLYDGNIYLVLEQAFSKTGRQQGKVTVKAKNMRTGARVELTFTGGEKVDKAMIERKEMQYLYNDGNDAYLMNTETYEQVSIPMTRLEWEKNFLVDGLMINMTEFENEVLGIDLPVKVELTVVEAEAAVKGDTTSGAQKKAILETGLEIMVPLFVNQGTKIIVSSADGKYVGRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATHB4_ARATH
Sequence: MGERDDGLGLSLSLGNSQQKEPSLRLNLMPLTTSSSSSSFQHMHNQNNNSHPQKIHNISWTHLFQSSGIKRTTAERNSDAGSFLRGFNVNRAQSSVAVVDLEEEAAVVSSPNSAVSSLSGNKRDLAVARGGDENEAERASCSRGGGSGGSDDEDGGNGDGSRKKLRLSKDQALVLEETFKEHSTLNPKQKLALAKQLNLRARQVEVWFQNRRARTKLKQTEVDCEYLKRCCDNLTEENRRLQKEVSELRALKLSPHLYMHMTPPTTLTMCPSCERVSSSAATVTAAPSTTTTPTVVGRPSPQRLTPWTAISLQQKSGR
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein ATHB-4, HD-ZIP protein ATHB-4, Homeodomain transcription factor ATHB-4.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMN_STRPN
Sequence: MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVMGIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKECVLAFYDTLKKKGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAVAAVNP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.