PharMolix/UniProtQA huggingface dataset:
Protein: DPOLA_TRYBB
Sequence: MEDWVSCRSEEQKRCEEKGQSTFDESEEEQWRRLKEEAMIDSDDSEGAAGDEGAVVLAEAKRRKPRKSGKVIATQKCAQPQNQHRHQQKLTKSLSTYDMENLLKQYRNISAEEEDEVDVDITKFLQDDGVDSEDGEGPSVTATELLSSLISGRSADTNKTEELADSFPLANLNDEVFTYENEAAVKKTPRNKEKRTNKSGANYVIKETVVEELNVVTDLAEVRTGSQHASTDFLNGCPPKALFYWFDAKEQPHTLTAPGTILLFGKVCMNEEDEEFRSCCVRIQHVHRNVFLLPKEGSTDAEVVQEINAICRGSGIEERRIKFVERYYAFEEPGVPREKNRWAKLVYPGRYPPFPNKGGLTHVQVVVGASRSLLELFLIKKRLMGPSYLEIEHLVTAMDRVSHCKTEFLVPSPKDIKVYNSSKPPPPFTVASIQLHAQLDSDGVKNEVIAASIALYGDVSIDGERKPNITECFTGVRQLSPDAPLPLDLETYCLSKRMPGVHRFINERALLTWFAETLAALDPDIIVGHNIIGYTVETLLNRYQELNIVRWSTIGRLDVRRFPRIQGNNFNLAIEKEACVGRLVVDTYLLAREYYKSTNYKLLSLSTQMEIKGITDNRGHFEPGSTVLVKDSMMSSEALCPILLQLLNCAVLSFNVASFLDVIPLTKRLTLLAGNLWSRTLYGARSERIEYLLLHAFHNLKFVTPDKKKRDLKRGREDDDDEGKRKTKYQGGMVLEPKSGLYSEYILLLDFNSLYPSLIQEFNVCYTTIDRDENTVSAEVPPPESLICLSCRAAGLPSPCLHKCILPKVIRGLVDSRREIKRMMKSEKDPGNLAMLEIRQLALKLTANSMYGCLGFEYSRFYAQPLAELVTRQGRLALQNTVELIPQISPSIRVIYGDTDSVMIQTGIKDDIVKVRNLGFEIKGKVNQRYQSLELDIDGVFRAMLLLRKKKYAALSVVDWQGEGKVYKREVKGLDMVRRDWCPLSQHVSDAVLKRILNAEGGEDILDFVIKYMKGVAQDVRSGNVYPLEEFVISKSLTKEPESYHGTGYPHAVVALRMKQRKEGVRVGDLIPYVICEGDEHIDDKAYHIDEVRRSDGLSVDVEWYLSSQLYPPVMRLCEHIQGFVPEQLSEAMCIASHMRTERDVKEEDTANDFSHCSIFKSRALSECFPTATALQVQCTHCQLVVPVDPHKYINDMFSSREKPPPTAPFELYVCFNCGRSLPLAYLANCMTQMCHTIIRQFYCSGGNVASVRALRAQFTYLRAMFDVPQALNCPSAVKNAHRVLSLRCLGTDRKLYTLADVERFPDVEPVDPLLACAESFYRRIDHLFVSLDKLFDTP
What is the function of this protein?
Polymerase alpha in a complex with DNA primase is a replicative polymerase.
What are the official names of this protein?
DNA polymerase alpha catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEMP1_DROME
Sequence: MFPQIWGVIFLFTPTVFSELFKDPELLAGFYQGDIKAHPIRTRNGIVNQIYHWPNRTVPYMIEDDAFADSHYREILRAISIIEENSCVIFKPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSRNGQPTIVPLREGAENMGQRFYMSEKDIRKLNKMYRCPDHV
What is the function of this protein?
Seminal fluid metalloprotease which is transferred to females during mating and is required for processing of two other seminal fluid proteins Acp26Aa and Acp36DE in mated females.
What are the official names of this protein?
Seminal metalloprotease 1.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into seminal fluid.
Protein: GPMA_CHLMU
Sequence: MTLLILLRHGQSVWNQKNLFTGWVDIPLSQQGIQEALTAGEAIKNLPIDCIFTSTLVRSLMTALLAMTNHSSKKIPYIIHEERPDMSRIHSEKELEQMIPLFQSSALNERMYGELQGKNKQEVAEQFGEEQVRLWRRSYKIAPPQGESLFDTAQRTLPYFQKRIFPLIQQGKNIFISAHGNSLRSLIMDLEKLTEEEVLSLELPTGKPIVYEWTEQKFTKSALSFG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: VA0D1_HUMAN
Sequence: MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002, PubMed:28296633, PubMed:30374053).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:30374053).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).  May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 1, V-ATPase subunit d 1, 32 kDa accessory protein, V-ATPase 40 kDa accessory protein, V-ATPase AC39 subunit, p39, Vacuolar proton pump subunit d 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: MQO_HAHCH
Sequence: MTVKKADVLLVGGGVMSTTLGTMLMQLDPSLNIVMVERLDHVAHESTYGWNNAGTGHAGYCELNYTPETGDGDIEITRALAINASFEVSLQFWSYLVERGGLPSPDEFINTCPHESFVWGESDIAFLRKRHQLLSAHHLFKDMEFSDDPRTLQDWMPLVMEHRDPMQKVAATRVRYGSDVDFGSLTRNMVEHLQKNANFELLLSHPVKSLKQTSDGRWNVQLSDSRNGGSKTIDAGFVFLGAGGGALPLLQKSGIAEGDGYGGFPVSGQWLVCKKPDIVKRHYAKVYGKAAIGAPPMSVPHLDTRIINGEPALLFGPYAGFTTKFLKTGSSFDLFGSIRANNFGPIMSVGINNMDLTRYLIKEAMQSHSDRVKSLLNYFPEAKEDDWTLAEAGQRVQIIKRDAQGRGKLEFGTELVASKDGTLAALLGASPGASVAVKAMVDVIERCFKDRLSSADWTAKLKEMIPSYGESLVDNAELLHSVRSRTLSVLGLDKKRL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: NRDR_CROS5
Sequence: MQCPYCQHTNSRVLESRSSEGGQSIRRRRECLNCKHRFTTYERIEFVPITVIKHDGKKESFDASKLLRGMVRACEKTGISHQRLETIVDDIEAYLQQRPQREVTTHEIGQLVLKYLREENEVAYIRFASVYGRFKGIKDFVETLDQLQEETISSPMSQWSKSSTRDRDQSQTSPCLSLTHNGSENSR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FND11_MOUSE
Sequence: MNFQVTGLALDKMKLDSPHSFLDAEEVEEAEDQQLLEPEAWRTYMERRNVLREFLTTDLSPQLLKRHHARMQLLKKCSYYIEILPKHLALGDQNPLVLPNTMFQLIDPWKFQRMKKVGTAQTKIQLLLLGDLLEQLDHGRAALDALLEAPDPRPFLAGWGLVEQQLADLSVVMDNFLAMMVPGHLHVKHRLVSDIGATKIPHIRLMLSTKMPVMFDRKESVAHQDWVSLRWFVTIQPAAPEQYELRFKLLEPRTQQECTQCGIVPVAACTFDVHNLLPNRTYKFTIKRAESYTLVYEPWRDSLTLQTTPGPPEGPAPRLGEPPAGL
What are the official names of this protein?
Fibronectin type III domain-containing protein 11.
Protein: RS8_MAGSA
Sequence: MSMTDPLGDLLTRIRNGQRANKSTVVSPASSLRANVLEVLKREGYIRGYARSELRPGVAQLSIELKYHEGQPVIREISRVSTPGRRVYSKIADLRRVANGLGITILSTPRGVMSDTEARTQNVGGEVLCEVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: END4_BUCAT
Sequence: MNYIGAHVSSSGGLEKTVLRAIQIKATAFSFFTKNQRQWFSPPLIQKKIDQFKAMCIKYSFQPQQILPHSSYLINLGHPIDELLRKSRKSFIDEMIRCSQLGLIFLNFHPGSHLNKITENACLLRVSDSINIALEKTQNVIAVIENTAGQGTNIGYCFEHLSEIIKNIDDKSRVGVCIDTCHLFASGYDLRTKKDCENTFEKFNSLIGLKYLKGIHLNDSKKKINSRVDRHESLGLGEIGTAAFTWIIKNENFSNIPIILETANPMIWEEEIDWLRSQKKL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: FAHD1_DICDI
Sequence: MNKFWETGRKIVAVGRNYAQHAKELGNEIPSEPFFFLKPTSSYLLQGTGPIEIPLESSDIHHEVELGIVIGKKGRDIDLKSAMDYVSGYTLALDMTSRDQQSIAKAKSLPWTVSKGYDTFCPISGFIPKDKIKDLNNVELWCSVDGQIKQKGNTNQMIFDVPHLIQYISSIMTLESGDLILTGTPSGVGPVKPGQVIKCGITGLDTDMQFDIILRKRN
What is the function of this protein?
Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro.
What are the official names of this protein?
Acylpyruvase FAHD1, mitochondrial, Fumarylacetoacetate hydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol.
Protein: PNPH_RAT
Sequence: MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN
What is the function of this protein?
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).  Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (By similarity).
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUE1_YEAST
Sequence: MEDSRLLITLILVFGVIFLKKFFQSNQHPSAQRLSATGVNAHGRPQGSTQNALRRTGRVNGGHPVTTQMVETVQNLAPNLHPEQIRYSLENTGSVEETVERYLRGDEFSFPPGFEPSRAPMGANAAVDNNAAGGGEFNDPRKKNMICAENLLDKFHVDLNEDMSNLSFKDLDIEERKRLLVWQARKNLETKLQSDKDLQSLLT
What is the function of this protein?
Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway.  Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system.  Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and to the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M).  Has also a role in cold adaptation, perhaps through effects on sterol biosynthesis.
What are the official names of this protein?
Coupling of ubiquitin conjugation to ER degradation protein 1, Kinetochore-defect suppressor 4.
What is the protein family that this protein belongs to?
Belongs to the CUE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RS3_PHYPY
Sequence: MGQKTNPNGLRLGIIRTWESQWCVNDKEIPNLIKEDFLIRKLINNFTKKSAISQIDIERLKEKNKNRITISVHTAKPGVIIGKDGDTRNKLVAKLKELTQKDVNLNVLEVKNSDKNALLIAQNMAEQLENRMFFRRVQKMAIQKALKAGAKGVKTLISGRLGGAEIARSEGHAEGRVPLHTLRADIDYAAVEAHTTYGVLGIKVWIFHGEVLPGQTILDTRKPFASQSSNTPNRRPRNFKGGNNNHVNAKKN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DXR_ACAM1
Sequence: MKAITLLGSTGSIGTQTLDIVAQYPDQFRIVGMAAGRNIELLSQQIRQFRPEIVAIADPNQLSDLKDAIADVDPQPQLLAGEAGVVEVAAYGDAESVVTGIVGCAGLLPTIAAIKAGKDIALANKETLIAGGPVVLPLVEKHGVKLLPADSEHSAIFQCLQGVPEGGLRRIILTASGGAFRDWPVEKLPEVTVADALKHPNWSMGKKITVDSATLMNKGLEVIEAHYLFGVDYDHIDIVIHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYSLSWPERIATDWEQLDLVKSGDLTFREPNHQKYPCMQLAYDVGRMGGAMPAVMNAANEQAVALFLEEKISFLDIPKVIETACDRYQSQNTLQPSLEDILAADQWARQEILTISQSQTPVVTASPQLSAI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TMUB1_HUMAN
Sequence: MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGGDPLPQPSGTPTPSQPSAAMAATDSMRGEAPGAETPSLRHRGQAAQPEPSTGFTATPPAPDSPQEPLVLRLKFLNDSEQVARAWPHDTIGSLKRTQFPGREQQVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPNPPCPPGSEPGPSGLEIGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMYRP
What is the function of this protein?
May contribute to the regulation of translation during cell-cycle progression.  May contribute to the regulation of cell proliferation (By similarity).  May be involved in centrosome assembly.  Modulates stabilization and nucleolar localization of tumor suppressor CDKN2A and enhances association between CDKN2A and NPM1 (By similarity).
What are the official names of this protein?
Transmembrane and ubiquitin-like domain-containing protein 1, Dendritic cell-derived ubiquitin-like protein, DULP, Hepatocyte odd protein shuttling protein, Ubiquitin-like protein SB144.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Postsynaptic cell membrane. Recycling endosome. Cytoplasm. Nucleus. Nucleus, nucleolus. SUBCELLULAR LOCATION: [iHOPS]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus. Note=iHOPS is proposed to be the shuttling form across different cellular compartments. XPO1-dependent exported from the nucleus in dividing cells. Predominantly nuclear during growth arrest.
Protein: AROE_SULIY
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKGGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYGIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS4_STRP6
Sequence: MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DAPD_HELPY
Sequence: MINKFKNFVSNYQQSNHYKEPLGFGIARVDIAPISKKILCATYPVLNWKDENLGSYAVFCNSLSKEKILKESASERVIEIDESFVLKALDFYTPFLNEAYSNKMAHKNIQVVLELLKALEENRLKNSDGESLYRLVILYEDKPCESVESAYMKLLALSLGKAPLRSLNLEGIFNQLSNAAWSGNKPYELEWLRMNEVALKMRDHFPSIDFIDKFPRYLMQLIPEFDNIRLLDSSKTRFGAYLGTGGYTQMPGASYVNFNAGAMGVCMNEGRISSSVVVGAGTDIGGGASVLGVLSGGNNNPISIGKNCLLGANSVTGISLGDGCIVDAGVAILAGSVIEIEENEFKKLLEVNSALEKHANNLYKGKELSGKNGVHFRSNSQNGKLIAFRSVKKIELNQNLH
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_FRATM
Sequence: MLDKIWYRSKPNLLSRVLQPISLVFIDIANKRKIKQQLKQYKSKIPIIVVGNISVGGTGKTPVVRMLAQQYLAQDKKPAIISRGYGAKADNYPFEVTSGTLATQCGDEPAMLFDALQAQVPIVIAPERVQAVKYIEKNFPDTDIIMSDDGLQHYKLARDKEIVVVDAIRMFGNKLCLPAGPLREPIERLKEVDQIIVIGNCSDKDKELLKNYKNVTYAKVVATEFVNILTAKKVAKTEFNHQNAIAIAGIGNPTKFFKTLEESAINITAKKVFKDHHKFTQSDFEGIDSDITVVMTYKDAIKCKNFAKANWWYLDIALDINV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: OPI10_SCHPO
Sequence: MFGAICAGRLVQTNLQQVADNQFVFQLDSAESLNHIVVFLLPNSPFPVGMGAKVYFQWPGKPFQFLGYLTNEKPSAIFRLKNTIQTLSENENCVGITAMLGISVEPLTNFTETPAVSTSASNVIAKPLPPVTSVAQKILTNLYNFLASFATSQLPPNSIGLGDLRPNDTFIPLRVFQDWHAKFLNKLSNNPNFLDSEDQI
What are the official names of this protein?
Protein OPI10 homolog.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: RSMJ_ECO55
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_SHIDS
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFDNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRHM_PENBI
Sequence: MHPDAQLKTALKNGFDPKLLYKEPLTTVKEPVCSILEKHSKVPVDKVVSHVNEVRDRAFAVFPYACIGQFSFVELSIADSPCYREMLERTKQGHKLLDLGCAFGQELRQLIYDGTPPTNLYGSDIQQDFLSLGYELFLDRAILPDSQLIAADVLDKQSALFQRLAGELNIVYISLFLHVFDFEKQITVAQNVLDLLKAEPGSMIVCRVTACRDQEVLAATQERMPYYYHDLASWNRLWEEVQKQTGVKLSVESWEQPDELVKKHPLPGIYILGSSIRRL
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture (PubMed:27602587).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase prhL (By similarity).  Synthesis of DMOA is followed by farnesylation by the prenyltransferase prhE, methylesterification by the methyl-transferase prhM, epoxidation of the prenyl chain by the flavin-dependent monooxygenase prhF, and cyclization of the farnesyl moiety by the terpene cyclase prhH, to yield the tetracyclic intermediate, protoaustinoid A (By similarity).  The short chain dehydrogenase prhI then oxidizes the C-3 alcohol group of the terpene cyclase product to transform protoaustinoid A into protoaustinoid B (PubMed:27602587).  The FAD-binding monooxygenase prhJ catalyzes the oxidation of protoaustinoid B into preaustinoid A which is further oxidized into preaustinoid A1 by FAD-binding monooxygenase phrK (PubMed:27602587).  Finally, prhA leads to berkeleydione via the berkeleyone B intermediate (PubMed:27602587, PubMed:29317628).  PrhA is a multifunctional dioxygenase that first desaturates at C5-C6 to form berkeleyone B, followed by rearrangement of the A/B-ring to form the cycloheptadiene moiety in berkeleydione (PubMed:27602587, PubMed:29317628).  Berkeleydione serves as the key intermediate for the biosynthesis of paraherquonin as well as many other meroterpenoids (Probable).  The cytochrome P450 monooxygenases prhB, prhD, and prhN, as well as the isomerase prhC, are probably involved in the late stage of paraherquonin biosynthesis, after the production of berkeleydione (Probable).  Especially prhC might be a multifunctional enzyme that catalyzes the D-ring expansion via intramolecular methoxy rearrangement, as well as the hydrolysis of the expanded D-ring (Probable).
What are the official names of this protein?
Methyltransferase prhM, Paraherquonin biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: IXTPA_KORCO
Sequence: MIFASSNRHKYEEFRRMLSDLIDLKFLEVDYLEPQGEDTREIVVTSAKWLSNYIREPFFIEDSGLFIEALNGFPGPYSSYVFKKIGNEGVLKLMNGVENRRAFFISVIALSYGRGIEVFEGRVQGTIAREVRGGGWGFDPIFIPNGSNKTYGELGDEKDRFSHRGASCRKLREFLMRFGSDRLP
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: NUOB2_RHOPT
Sequence: MTMTPQHPGMPDEQRSVEEHMALSSLFTTLEDLTAWSRKHSLWPFNFGLSCCYVEQVTVLTPVYDQARFGAEVIRASPRQADLLVVSGTVFHKMAAPLLRLYEQMRAPRWVIAMGACACSGGMYDIYSVVQGVDRFIPVDVYIPGCPPRPEAVLDALIMLQQQVGSERRPLGVTVGNTAGLGFDAPRRRDQRRDERMAQTLLDPPESL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y3359_MYCA1
Sequence: MDAHLENGAGIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITRMVDLGMDAGSRITQLAVVMDVRSRGFTGDLDSVRTELATRNIAPRVVFMEASDDMLVRRYEQNRRSHPLQGDQTLAEGIAAERRMLAPVRATADLIIDTSTLSVRALRETIERAFGGGASATISVTVESFGFKYGLPMDADMVMDVRFLPNPHWVDELRPRTGQDPAVRDYVLGQPGAAEFLDAYHRLLSLVVDGYRREGKRYMTIAIGCTGGKHRSVAIAEALMQRLQAQHGEAQLSVRVLHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein MAV_3359.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PPK5_MASDA
Sequence: GGSGSGETSGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, MasDa-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.