PharMolix/UniProtQA huggingface dataset:
Protein: COFH_HALSA
Sequence: MTDASALDFDVVPSTDQSFENALANARDGRRLTVADGIELITTGTDTDGIDPRRKELVLEAADRRRADVVGDDVTFVANLNNNVTTACNTGCLFCNFKDTAHRFETEHEAAHGGFTKTPAESKATVADAIQRGVSEVTSVSGLHPAFGLNEAHRDALDPDDPDHNYKPPEAYDTDPTTYAAQIAAMSEAGAHVHSITPEEAHHAQRGVSWGYDEVYETLADAGLDTVPGTAAEILVDEVRDVICPGKMTTDEWVAAMEAAADAGLGTTATIMYGHVENAAHRIHHLDVIRALQDRTHNITEFVPLSFIHEQTPLYERGVVDGGASDAEDELMIAVSRLFLDNIDHIQSSWVKFGDAKGLALLNCGADDFMGTILSEEITKRAGGQHGEFRSVADYAEMISAIGRTPVERSTDYTTRHVINPDADTIGPHVGPNADGTPLVSERAGTPPHSAGD
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: TXE1A_SCOMO
Sequence: MNPKLCMLLLVCLMAFYVIETVQAKLTGECPAELEKECLNRRCASPCCKNNKCHCGCGRKK
What are the official names of this protein?
U-scoloptoxin(14)-Sm1a, U-SLPTX(14)-Sm1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ROA2_HUMAN
Sequence: MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY
What is the function of this protein?
(Microbial infection) Involved in the transport of HIV-1 genomic RNA out of the nucleus, to the microtubule organizing center (MTOC), and then from the MTOC to the cytoplasm: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) sequence motifs present on HIV-1 genomic RNA, and promotes its transport.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2/B1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm. Cytoplasmic granule. Secreted, extracellular exosome. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661). Component of ribonucleosomes (PubMed:17289661). Not found in the nucleolus (PubMed:17289661). Found in exosomes following sumoylation (PubMed:24356509). SUBCELLULAR LOCATION: [Isoform A2]: Nucleus. Cytoplasm. Note=Predominantly nucleoplasmic, however is also found in the cytoplasm of cells in some tissues (PubMed:17289661).
Protein: COR1C_MOUSE
Sequence: MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPAANKKSELSCAPKKPTDTASVQNEAKLDEILKEIKSIKETICSQDERISKLEQQLAKMAA
What is the function of this protein?
Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed:25074804, PubMed:25925950).  Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed:25074804, PubMed:25925950).  Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (PubMed:27178841).  Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (PubMed:27178841).  Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission.  Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (By similarity).  Required for normal distribution of mitochondria within cells (PubMed:27178841).
What are the official names of this protein?
Coronin-1C, Coronin-3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Endosome membrane. Note=Colocalizes with the actin cytoskeleton in the cytosol, and especially in the cell cortex (PubMed:19651142, PubMed:22364218, PubMed:25074804, PubMed:27178841). Colocalizes with F-actin at the leading edge of lamellipodia (PubMed:22364218). Partially colocalizes with microtubules and vimentin intermediate filaments (PubMed:27178841). Localizes to endosome membrane tubules/buds (By similarity).
Protein: LIP2_STAAS
Sequence: MLRGQEERKYSIRKYSIGVVSVLAATMFVVSSHEAQASEKTPTNAAVQKETLNQPGEQGNAITSHQMQSGKQLDDMHKENGKSGTVTEGKDTLQLSKYQSTQNSKTIRTQNDNQVKQDSERQGSKQSHQNNATNNTERQNDQVQNTHHAERNGSQSTTSQSNDVDKSQPSIPAQKVLPNHDKAAPTSTTPPSNDKTAPKSTKAQDATTDKHPNQQDTHQPAHQIIDAKQDDTVRQSEQKPQVGDLSKHIDGQNSPEKPTDKNTDNKQLIKDALQAPKTRSTTNAAADAKKVRPLKANQVQPLNKYPVVFVHGFLGLVGDNAPALYPNYWGGNKFKVIEELRKQGYNVHQASVSAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYKGIMPNWEPGKKVHLVGHSMGGQTIRLMEEFLRNGNKEEIAYHKAHGGEISPLFTGGHNNMVASITTLATPHNGSQAADKFGNTEAVRKIMFALNRFMGNKYSNIDLGLTQWGFKQLPNESYIDYIKRVSKSKIWTSDDNAAYDLTLDGSAKLNNMTSMNPNITYTTYTGVSSHTGPLGYENPDLGTFFLMDTTSRIIGHDAREEWRKNDGVVPVISSLHPSNQPFVNVTNDEPATRRGIWQVKPIIQGWDHVDFIGVDFLDFKRKGAELANFYTGIINDLLRVEATESKGTQLKAS
What are the official names of this protein?
Lipase 2, Glycerol ester hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_OCHRO
Sequence: MTNIRKTHPLMKIINHSLIDLPAPSNISAWWNFGSLLGLCLGIQIITGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGIYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPTGIISDADKIPFHPYYTIKDALGFLLMISLLLTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIAILAAMPLLHTSKQRSMMFRPISQTLFWILVADLFTLTWIGGQPVEHPFIIIGQLASFLYFFLILVLMPASSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYD_ECOSE
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_LISMH
Sequence: MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALKREDYPEDGVIIKAYFLKTSEFVEQIPEIEQTLKNLTTFDIPLGKFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPTTQLCIRALSDYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKTNVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKNAGLIIEKIEQQGDWVAIISKRGVE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_BLOPB
Sequence: MVHSKSLRIAFFGTTSFAAWHLHTLAHLSTHQIIAVFTQEIQISTCKSFLSLHKIAKKYNISLFQSRTLSISDIIYIIKKINVDLIVVVSYGLILPQEILNIPRLGCINVHGSLLPRWRGPAPIQRALEYGDSITGITIIQMDLGIDTGDILHIMPCKIFPKDTSCTLSNRLVNIGSAMLSQVLDQFILGTFTLIPQDSTYATYAHKLNKQEARINWNLSAIQLERCIRAFNPWPISFFQIKNDRIRVWDAEVSNQNINNYSSSTSILPGTILAAHPNGIYVVTGSGILILTMLQISGKKITSVRDLLNAYKEWFKPNSVLE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: METK_AMOPR
Sequence: MQQNTRYLFASEAVSRGHPDKACDQVSDRVLDYCLQAEKKCKKASRVALETTIKGNVVGLFGEVTCQKTFPTISWFRELVTEIGYSREDLDLDPTTCSVHINVRGQEAEIRGVVHNQERAAKETLGAGDQGLMFGYATDETPERCPCLWFLLRRFKLALRSKFEEARKKKIELAVAKGIKVSQVDATPELRDTIDFWWLHTDAKSQVIIEYEDDSGALKPITARVAVLSVQHSKFVTHDQYEDRLPQLVKGVLDEYGMHSEATEYLINIKQKTSGYGWTVGGPNADAGTTGRKIIVDTYGGHGAHGGGAFSGKDPSKVDRSAAYYARYVAQNLVRAKLCRRVLVQVSYVIGKPEPLNIYVNTYGTGTHSDSELLEIINKNFDFRPGFIIEELDLLNPDRIKYVETAYHGHFGRPEFPWEQEKTLTL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER_THETR
Sequence: AHIITDECISCGACAAECPVEAIHEGTGKYEVDADTCIDCGACEAVCPTGAVKAE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: FB277_ARATH
Sequence: MATTISNLPRELIEEILSRVPLRAMKAMRLTCKSWNNLSKSESFMKMHIGKAATREEKTMMVAVMPHTLALVSVVVDGVNPSTELKGQFSFLDKEFFIYRVIHYEGLLLCILKDATRIVVWNPYLGQERWIQIRYSHRPHGVDHFKYAVGYADKVSCRSVKLLRFLDYFHKASDKPFFWYEIYDFDSCLWTTLDITPHWGISWTYPRVSLKGNTYWPAREMNTKGFQDHIICFDFTSERFGPLLPLPRAQGCHVSLSCVKEEKLAVLLKHRLHHDSYEYEFEIWITTKIDVEMVSWSKFLRMDMRPKIKLPLSFYVDEEKKVFMGFDHGEYPKLFLNIIGETGFLRKLDLGVHEGHRSPCSYVPSLVQIKHPAGDKMIKQSSLEDRRFAQNSLRLAAIEKLIN
What are the official names of this protein?
Putative F-box protein At5g41500.
Protein: PGK_ARCFU
Sequence: MMIDGLPTLDDIPYRGKHVLLRVDINAPIVNSTILDTSRFESHIPTIEALEDSKLVLLAHQSRPGKKDFTSLESHASTLSKLLGKRVEYIDEIFSKGVLRRIKEMENGEVILLENVRFYSEEQLNRSAEEHAECHMVRKLSTAFDLFVNDAFSASHRSHASLVGFVPVLPSVVGRLVENEVTALSKPLKGEGRKIFVLGGAKIKDSVKVLKNVLENNIAEKVVLTGVVANYFLMLKGYDIGEVNRKVVEDNKEDVSDEEMINILKKYSDKIILPIDLGIEKDGVRVDIPLEKFDGKYRIMDIGLETVNQLSEIIPKYDYVVLNGPAGVFEDERFSLGTYEILRAATRAGYSVVGGGHIASAARLFGLSDKFSHISTAGGACIRFLSGEKLVALEVIKEYWAKKWGKS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_CAUVC
Sequence: MTTPQQPHGPLRSFGRLKSRPVKPRQQALLDTLLPEIAVPTGPFQPLDLMPEAKAVWLEIGFGGGEHMASQAGRNPETLVIGAEPFVNGVASAVRHVEEQALKNVRIHEGDARDVVDWLPDACLDRVFIMFPDPWHKARHNKRRLIQPEFVAKLARVMKPGAALRFATDWADYAEWTTERVLADPSFRFADEAADRNAIPADHVTTRYEEKKLGDCAPVFLDFTRG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SYGA_SALNS
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYCC_RHIS2
Sequence: MSWSRHKSLQRIRSFRASAPAAAINLSNFDLSYMTARATTIQARRKAGGKSEPLIFDVPPDSAVLVEGVHVYIQLLDFASAMTERERETEASHRRVLSMLHLNYAACDQVAEEFEAQRVDFHGARMHAVIVSPPGPGNERDRAERALAFADAAKRAIEEVGRTTENGRYSTRVRVGIDSGSAVAVNSGTQDEREPLFLGAPANYAAKLAEGDEEGVFMSNRIRKDLGLPQLSSFDTLAAERASRTSSVGETGLSANTSFQSKRLSDAAIMTAASRARNSFILNVGTDANFSFHRHTPPLSTIDFALLTPSNSVRMGLMSIFGDIDGFTKYVDECIAAQRIGEMVSNLHVIRSELAATLSQDFLGRKVRFIGDCIHGLLATGTSYETDASGSVVASVKAAGGMRSSFELCQEELGGIENLGIAIGLEYGETPITRIGIRGDRSVRCSVSRAVSRSEELQGGCTGDQTALGPTALGHAPTSIRRLFAGGVAMGLDAGSVDEHLGSPPIVRSGEVSAAAAPYDSGE
What is the function of this protein?
The pyrimidine cyclase gene of a two-gene Pycsar system, generates cyclic UMP (cUMP) from UTP, has little to no activity on ATP, CTP or GTP (PubMed:34644530).  Expression of this and effector RsPycTM (AC A0A4R2UGS4) probably confers resistance to some bacteriophage.  The genes are probably only expressed in response to bacteriophage infection (Probable).
What are the official names of this protein?
Uridylate cyclase, Cyclic UMP synthase, cUMP synthase, RsPycC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Pyrimidine cyclase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_SODGM
Sequence: MSMQDPIADMLTRIRNGQAANKTAVSMPSSKLKVAIANLLKEEGFIEDYKVEGDTKPTLELVLKYFQGKPVVETIQRISRPGLRIYKKKDALPKVMAGMGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COQ7_NITEC
Sequence: MLNVDKLIIGFDNALRTLLAPAATLRPIPGKDLPENELSKIEKRESAALMRINHVGEVCAQALYQGQALTARNEQVRQALDQAAREETEHLAWTERRIAELGGHKSFLNPLWYGGSFALGLVAGVLGDKWNLGFLAETERQVEAHLADHLQRLPHQDVRSRAIVSQMKVDEACHATMAVSYGGGPLPVPIKAVMKFSSGIMTRTAYWV
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRB_CUPPJ
Sequence: MTKTFRNPQLTKNGELKHLLSIEGLSRDMITHILDTASQFVSLSDSDRDVKKVPLLRGKSVFNLFFENSTRTRTTFEIAAKRLSADVLNLNINASSTSKGESLLDTINNLSAMSADMFVVRHASSGAPYLIAEHVAPHVHVINAGDGRHAHPTQGLLDMYTIRHFKKDFTQLRVAIVGDILHSRVARSDIHALTTLGVPEVRAIGPRTLLPSGLEQMGVRVFHNMEEGLKDVDVVIMLRLQNERMSGALLPSAQEYFKAFGLTPERLALAAPDAIVMHPGPMNRGVEIDSAVADGPQSVILNQVTFGIAVRMAVMGIVAGNSD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: DAPA_ECO57
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLP15_PHYCP
Sequence: MYSWYFPKDSPSTGMGHRHDWEHAIVFIDNPDVPEPKILACSVSSHAGYKKYNPCPPWVIDGTSLKVRYKHGWPLNHDLDTTGDAGTFQDLIMWDQMTEDARRALNSVHFGSANTPFNDGNFKPKLEKAWPF
What is the function of this protein?
Secreted effector that contributes moderately to virulence during infection by P. capsici.  Causes only small yellow areas at 3 days after inoculation of host C. annuum leaves; these areas expand somewhat and became necrotic at 7 days after inoculation.  Leads only to chlorotic areas, without necrosis at 7 days after non-host N. benthamiana leaves infection.
What are the official names of this protein?
NLP effector protein 15, Necrosis-inducing protein 15, Nep1-like protein 15.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ODP1_BUCAP
Sequence: MSEKLYNYDVDPVETNDWVQSIESVIREEGLERAKFLIEKILKKSKITRANFFKCFFTSDYINTISSEEEVEYPGDLILEKRIRSAIRWNAIMMVLRASKKDLELGGHLSSFQSSATIYEVCFNHFFRSKNDEDGGDLVYFQGHIAPGIYARSFLEGRLSKKQIDNFRQEVDGKGLSSYPHPKLMPNFWQFPTVSMGLGPLCAIYQAKFLKYLQNRELKNTSKQTVYAFLGDGEMDEPESKGAISIAVREKLDNLIFVINCNLQRLDGPVVGNGKIVNELESFFYGAGWKVIKVIWGGKWDSLLKKDKTGKLIQLMNETIDGEYQTLKSKDGAYVRKYFFGKYQETLELVKNMTDEEIWNLNRGGHDPKKMFNALKKAKEIKDKPTVILAHTVKGYGMGVIAEGKNIAHQIKKININGIIYIRDRFNIPISNEDIKELPYVVFEKNSKEYCYMHQQRKKLGGYIPFRLSKFTNALNIPDLIDFKSLLKEQNKKMSTTIAFVRVLNLILKNHSIKNLIVPIIADEARTFGMEGLFRMIGIYSSIGQKYVPQDREQLAYYKEEKKGQILQEGINELGAASSWLAAATSYSTNDFPMIPFYIYYSIFGFQRIGDLFWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCVSYDPAFAYEVAVIIQDGLRRMYGPLQENIYYYITTINENYYMPAMPQGVEKGICKGIYKLKTFYATELKVQLMGSGAILRCICKAGEILSNDYCITTDIYSVTSFTELARNGEDCERWNMLHPYEKKRIAYIKTVMNSSPAVAATDYMKLFAEQIRHYIPSNEYHVLGTDGFGRSDSRDKLRDHFEVSAYYIVVAALNLLAKLNNINKKVVEEAIIKFNINADKINPRLA
What is the function of this protein?
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, PDH E1 component.
Protein: KPCL_HUMAN
Sequence: MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP
What is the function of this protein?
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells.  In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation.  Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes.  In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation.  In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement.  Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs.  In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation.  Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1.  Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation.  In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis.  Promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.  Phosphorylates ATF2 which promotes its nuclear retention and transcriptional activity and negatively regulates its mitochondrial localization.
What are the official names of this protein?
Protein kinase C eta type, PKC-L, nPKC-eta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BURVG
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEASS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PYRH_LACP3
Sequence: MVKYNRIVLKISGEALAGEAGFGIKPPVIATIAKQIKEVHELGVQIAIVCGGGNIWRGETGAEMGMERAQADYMGMLATVMNALALQDNLESQGVPTRVQTSIEMRQIAEPYIRRKAIRHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEIGADVILMAKNNVDGVYSADPNKDTHAVKYESLTHMDIINKDLKVMDSTASTLSMDNDIDLVVFNLNEPGNIKRVVEGQKIGTTIEGRS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SALDC
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.