PharMolix/UniProtQA huggingface dataset:
Protein: GPMI_YERPP
Sequence: MSSTKKPLVLTILDGYGHREEQQDNAILNAKTPVMDVLWQQQPHTLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQDLTRLDKEIKEGDFFTNPTLTAAVDNAVKTGKAVHIMGLLSAGGVHSHEDHIMAMVELAAKRGATAIYLHAFLDGRDTPPRSAESSLKRFTAKFAELGNGRIASIIGRYYAMDRDNRWDRVQLAYDLLTQAKGEFTADNAVAGLQAAYARGENDEFVKPTVIQATGEADAAMNEGDTLIFMNFRADRARQITRTFVNAEFDGFKRDKVVNFGDFIMLTEYAADIKVACAYPPASLTNTFGEWLMKHDKTQLRISETEKYAHVTFFYNGGVEEPFKGEDRILINSPKVATYDLQPEMSSAELTEKLVSAIGSGKYDVIICNYPNGDMVGHTGDYDAAVKAVETLDNCIEQVVAAVKAADGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYVGNKAVKAVEGGKLSDIAPTMLSLMEMEIPQEMTGKPLFIVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PDAD1_METAC
Sequence: MITKLIPRKVFFTSGVGLHSEKLESFEVSLRDAGIEKFNLVTVSSILPPNCEIVTKEEGLKELSPGEVVFCVMSRISSNEPGKTLSTSVGCALPRDISKHGYISEYHAYEENAQDVGEHAKKLAGSMYSTWTNEAPLKTFSIPRSSSVQESGDWMTVISAAVFII
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase 1, PvlArgDC 1.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: STK40_XENTR
Sequence: MKRRASERDAGETSARSKALCSSISGSNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILSLEERGDKAGETQEERQGKMLLHTEYSLLSLLHNQDGVVHHHGLFQDRTCEIVEDLEANKLVRKMRKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLGERETVVIFYDVVRVVEALHKKNIVHRDLKLGNMVLNKRTHRITVTNFCLGKHLVSEDDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYSIPEDGRVSESTVCLIRKLLVLDPQQRLTASEVLESLGAIISSWQSMSSLSGPLQVVPDIDHLTSLENSQEAKVTEESSQYEFENYMRQQLLLAEEKNTIHEAKNFPQKRHFGNFPPIRRLGYDAQPVSPLDAAILAQRYLPPPHMALSNSH
What is the function of this protein?
May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
What are the official names of this protein?
Serine/threonine-protein kinase 40, Serine/threonine-protein kinase lyk4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SUCC_LEGPA
Sequence: MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTRLVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRATRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQCRETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDDRENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFGGIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: P3IP1_PONAB
Sequence: MLLAWVQAFLVSNMLLAEAYGSGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCENLSCPETTSQALPASTTEIEEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGTLGYVLGITMMVIIVAIGAGIILGYSYKRGKDLKEQHDQKVCEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDPQEGSTPLMGQAGTPGA
What is the function of this protein?
Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
What are the official names of this protein?
Phosphoinositide-3-kinase-interacting protein 1, Kringle domain-containing protein HGFL.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYS_ALBFT
Sequence: MLDITTLRKDLDSVIARLETRKSPQAFLNVDTFRTLEAERKTIQMRTEELQGKRNTLSKQIGQLKAKGAAGQAESDAVMAEVAGLKAELETSATRLEQIQLELQALLLGVPNLPHESVPVGADEHGNVVVRSWSPDGKGPKAFDFEVKDHVDIGTPLGLDFELGVKLTGARFTVMKGLIARLHRALAQFMLDVQTQEHGYTECYTPYIVNAQSMRGTGQLPKFEADLFAAKKGGQEAEAAPDNSALYLIPTSEVPLTNFVRDVVLAEAELPVKLTAHTPCFRSEAGSAGRDTRGLIRQHQFDKVEMVQIVHPDKSYETLEQMTGHAEAILQKLGLPYRVMSLCTGDMGFGASKTYDLEVWLPAQNTYREISSVSNCEAFQARRLQARFKNAQGKNELVHTLNGSGLAVGRALVAVLENYQNADGSVTVPQALRPYVGGQKVLGATAMNDMDM
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STAAE
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVQFAKALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKGLYHVLHGSISPMDGIGPEDINIPSLIERLKNDEVSELILAMNPNLEGESTAMYISRLVKPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TYSY_MYCBP
Sequence: MSIVTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTYEDIVVKNYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAP1B_MACFA
Sequence: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL
What is the function of this protein?
GTP-binding protein that possesses intrinsic GTPase activity.  Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen.  Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.  Plays a role in the establishment of basal endothelial barrier function (By similarity).
What are the official names of this protein?
Ras-related protein Rap-1b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol (By similarity). Presence of KRIT1 and CDH5 is required for its localization to the cell junction (By similarity).
Protein: VQ8_ARATH
Sequence: MIPTRCNEINGSRPSSLKLAGESHTIKKTSSCKSKPRPHGRASPVIIYAHSPKVIHTRAEDFMALVQRLTGLDEIIRRNTSESSSSVVTEEVNVGDDNTAAPFSQDRTQRQKLTDMPLFTPSSMTLFGSPTQLMYMSPNRTDSFRPLVFKSE
What is the function of this protein?
May be involved in chloroplast development.
What are the official names of this protein?
VQ motif-containing protein 8, chloroplastic, AtVQ8.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTH_HELPG
Sequence: MTLLVGLGNPTLRYAHTRHNAGFDILDSLVSELNLSFAFSPKHNAYLCVYKDFILLKPQTYMNLSGESVLSAKNFYKTKELLIVHDDLDLPLGVVRFKKGGGNGGHNGLKSIDLLCSNSYYRLRVGISKGIGVIEHVLSKFHKNEEPLKNAVFEHAKNALKFFIESHDFNAMQNRFTLKKPLQIES
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_CLOBJ
Sequence: MKVKDFDFYLPEELIAQHPMEKRDEARLLVLDKKTGGIEHKIFKDILDYLTPNDCLVLNNTRVLPARLIGAKEETGGKMEFLLLKRKEKDVWETLVKPGKRAQIGARFIFGNGELKAEVIGMGEEGSRIVKFYYEGIFEEILDQLGQMPLPPYIKEKLDDKEMYQTVYSKEEGSAAAPTAGLHFTEELLKKIKEKGVKLAFLTLHVGLGTFRPVKVENIQEHVMHSEYYKMDKETAEIINDTKEKGGRVIAVGTTSCRTLETIGDIEGKVREQSGWTDIFIYPGYKYKVVDALITNFHLPQSTLLMLVSALAGRDNIMNAYNVAVEKEYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LR74B_MOUSE
Sequence: MKGPCEVQKNEDQEGEAAATGPQAETLEAERSWTADSHSALEAEGTHGLGERVMATLYLKSCRANSVVPVSCLLRQEGASELNLRHRGLGPQGVRALASVLTSNPYIKRLDLRDNGLCGAGAEALADVLRKNSIISDVDLSENQIGAAGLQAICTALALNPTVEKMQLQGNRLEEQAAQHLAALLLHHRGLKSLDLSYNQLNDLAGEILGPAVAENTGLTELNLSWNHLRGLGATAFARGLEANIFLKVLDISHNGFGDSGASAIGDALRVNNVLEELNMRNNRISVSGALKLGLGLQVNQTLRILIISKNPIRSDGCVGLLKSVRNNKSSALELLDVSDIQVSRECEDLASSMSEILPGLCIKRYTSRRKDWPQASTPSQPASAPSDSGL
What are the official names of this protein?
Leucine-rich repeat-containing protein 74B.
Protein: SMAG2_HUMAN
Sequence: MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI
What is the function of this protein?
Has transcriptional repressor activity.  Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A.
What are the official names of this protein?
Protein Smaug homolog 2, Smaug 2, hSmaug2, Sterile alpha motif domain-containing protein 4B, SAM domain-containing protein 4B.
What is the protein family that this protein belongs to?
Belongs to the SMAUG family.
Protein: RR11_CUSOB
Sequence: MVKLIPRISSRRNGRIRLRKNKHKIPQGVIHIQASLQNTIVTVTDVRGRVVSWASAGSAGFKGTTRRTPFAAQTAATNAIHTAINQGMREADVLIKGPGLGRDAALRAIRRSGIRLELILDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
Plastid 30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RL30_STRP3
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIRGMVTAISHLVTVEDVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PFF1_EMENI
Sequence: MDQTKPPRRNPLAFTPWPVTLITAVVYLAFVIPLLVIHHVVPSAPTSSPDGLNITEAWNDLQVLTAGYRPYNSRQNDKIHDWLLHRINEILGAAPPATTDEKKPDVFVFDDTRSNLTFARDNLAVYFEGTNILVYIRGEDDDQEQWWELPEGSPKGKGGVLVNAHYDSVSTGYGATDDGVGVVTCLQLVKYFTTPKNAPRKGLVVLFNNGEEDFLNGARVYSQHPLSRFPHTFLNLEGAGAGGRAVLFRSSDAEVAASYMRSKHPFGSVLGSDGFKAGLIRSQTDYVVFEGDMGLRGLDVAFLEPRARYHTDQDDTRHTSKDSLWHMLSTAVATTEDLVSDTSDRFDGPARNDHKIASGTGHQAVWFDLYGSTFVLFRLHTLFALSVTLLVVAPIVLLLTSIILTKVDKMYLFRTSIRPEGSLEVLPLYGDRGVIRYPFLLGIPTAVTIGLAYLLTKFNPYIVHSSQYAVWSMMVSVWIFLAWFVSRVADFARPSAFHRVYTLTWTFVVMWVLQVIATVYQDRWALGGSYFIFFAYAGTFLATWISYLELFALPRKSEYANHLRPVSRHASSHSSRRGLSEEDEEDEDEAPTESTSLLGSRQRTTFANYVRVNADTADLSDSEEHTQDVNVYGLEQRWSASLPKWLWLLQFLLAAPIVLILVGPIALLLTGSLHQTGQDGSSSLFIYIAIVALTTLLLSPMLPFVHRCTYHIPLFMLAVFAGTLIYNLVAFPFSDSNRLKLFFIQEVDLDTGLNTASLTGVQPFVHDVAVGLPSAAGQNVTCGPFGDRFKCSWTGIPPHVLTEDKPVEEWLSFEVSRSIDKPRHAQLQISGQNTRACKVVFDSPIKNFHVAGSAYDPRFPHTYAKGIKEIRLWSRVWDNTWTVDVEWFNPDSSSDHSKTSGSLTGQVVCLWSDYNQPGTIPALDEVRQYGPAWIGVSKLADGLVEGRKSFEIA
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GUAC_SALHS
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWAAFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: KTHY_CARHZ
Sequence: MRGKFITIEGVEGSGKTTQIQYIARYLTEKNIPHIITREPGGTALGKKIRELLLNPSYPVVPEAEILLYLADRAQHVGEKIIPHLDKGVWVISDRYFDSTLAYQGYGRGFDLTLLKSFIAFATKGLIPDLTVLIDLPPEVGLSRVKGRGEYDRLERETLEFHQRVREGFLQLARDQRFRVVDGRKKPEEIFWEIKGFLEGLNG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RL34_CLOB6
Sequence: MFMTYQPKKRQRKKEHGFRKRMKTSSGRNILRKRRQKGRKRLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: FIS_PHOPR
Sequence: MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVDDLYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: OBG_ACIC1
Sequence: MTTFVDRVVVHVRGGDGGNGCASIRREKFKPLGGPDGGNGGRGGDVVFVVDPGTTTLLDLHRRPHRRAAPGSPGQGNNKHGADGADLLIPVPDGTVVKDLDGQVLADLVGAGTRYVAARGGRGGLGNAALASARRKAPGFALRGEPGEERDVVVEVKSVADIALVGYPNAGKSSLIAAISAARPKIADYPFTTLAPNLGVVEAGEIRFTVADVPGLVRGASQGRGLGLEFLRHIERCAAVVHVVDCAAAEPDRSPLADLAAIRAELAAYASLDLGGPPLHERPQLVVLNKIDIPEARARAEAAARQIADAPVFLVSAVTREGLRELVFAMAGLVETARANRPAPEPPRIVLRPPAIAEPEFTVRRRGSAFIVDGEKPRRWVAQTDFSNDEAVGYLADRLARLGVEDELARLGARPGDEVIIGGVSFDYEPGIRAGVGHPFGPRGTDPRLHAAAPPATAHWAGDGDDDSAARDEEDG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPK3B_MOUSE
Sequence: MVRTRWQPPLRALLLLVLVWLPQSLSLDLIAYVPQITAWDLEGKITATTFSLEQPRCVFDEHVSTKDTIWLVVAFSNASRDFQNPQTAAKIPTFPQLLTDGHYMTLPLSLDQLPCEDLTGGSGGAPVLRVGNDFGCYQRPYCNAPLPSQGPYSVKFLVMDAAGPPKAETKWSNPIYLHQGKNPNSIDTWPGRRSGCMIVITSILSALAGLLLLAFLAASTTRFSSLWWPEEAPEQLRIGSFMGKRYMTHHIPPSEAATLPVGCEPGLDPLPSLSP
What is the function of this protein?
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells.  May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells.  It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
What are the official names of this protein?
Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35.
What is the protein family that this protein belongs to?
Belongs to the uroplakin-3 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Protein: BPHY_PSEAE
Sequence: MTSITPVTLANCEDEPIHVPGAIQPHGALVTLRADGMVLAASENIQALLGFVASPGSYLTQEQVGPEVLRMLEEGLTGNGPWSNSVETRIGEHLFDVIGHSYKEVFYLEFEIRTADTLSITSFTLNAQRIIAQVQLHNDTASLLSNVTDELRRMTGYDRVMAYRFRHDDSGEVVAESRREDLESYLGQRYPASDIPAQARRLYIQNPIRLIADVAYTPMRVFPALNPETNESFDLSYSVLRSVSPIHCEYLTNMGVRASMSISIVVGGKLWGLFSCHHMSPKLIPYPVRMSFQIFSQVCSAIVERLEQGRIAELLRVSTERRLALARRARDADDLFGALAHPDDGIAALIPCDGALVMLGGRTLSIRGDFERQAGNVLQRLQRDPERDIYHTDNWPQPSEDSPDGGDCCGVLAIRFHRQESGWIFWFRHEEVHRIRWGGKPEKLLTIGPSGPRLTPRGSFEAWEEVVRGHSTPWSETDLAIAEKLRLDLMELCLNHAAEVDRMRQRLIAVLGHDLRNPLQSISMAAALLSSSDTRTTELRQHISASSSRMERLVSQILDMSRLQSGIGLTVNPVDTDVSQLVRQIVCETDVAYPGLVIEIAIDPQVRAVVDPDRYAQVAANLLSNARHHGLPGRPVLVTLTRQGDEVCLSVLNETSGLSEAQLANLFEPFKRESADNQRNRNGLGIGLYISQAIAQAHQGRIDVDCRDDVITFCLRLPVRQAETGSSS
What is the function of this protein?
Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region.
What are the official names of this protein?
Bacteriophytochrome, Phytochrome-like protein.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the phytochrome family.
Protein: MYO1_ASPTN
Sequence: MGHSRRPVGGEKKSRGFGRSKAVADVGDGRQTGGKPQVKKATFESTKKKEIGVSDLTLLSKISNEAINDNLKLRFQHDEIYTYIGHVLVSVNPFRDLGIYTDKVLESYRGKNRLEVPPHVFAVAESAYYNMKSYNDNQCVIISGESGAGKTEAAKRIMQYIASVSGGSDSSIQHTKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLELEFNSRGEPVGANITNYLLEKSRVVGQITNERNFHIFYQFTKAAPQKYRDMFGIQQPQSYLYTSRSKCYDVPGVDDAAEFRDTLNAMGVIGMSEPEQDQVFRMLSAILWIGNIQFVEDDSGNAAIPDQSTVNYVAYLLEVDPGQVNKALTIRIMETARGGRRGSVYEVPLNTVQALAVRDALAKAIYFNLFDWIVERVNQSLTARGTVANSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKAEQDEYAREQIQWTPIKYFDNKVVCSLIEDKRPPGVFAALNDACATAHADSGAADNTFVGRLNFLSQNPNFENRQGQFIVKHYAGDVSYAVEGMTDKNKDQLLKDLLNLVGSSSNEFVHTLFPNQVNQDDKRRPPTASDKIKASANDLVATLMKAQPSYIRTIKPNDNKAPKEYNEGNVLHQIKYLGLQENVRIRRAGFAYRQTFDKFVERFYLLSPKTSYAGDYTWTGDAESGARQILKDTSIPQEEFQMGITKVFVKTPETLFALEAMRDRYWHNMAIRIQRAWRNYLRYRIECAIRIQRFWRRMTGGLELIKVRDQGHKVLQGRKERRRMSLLGSRRFLGDYLGIANKGGPGEMIRNGAGIGSDTVLFSCRGEVLVSKFGRSSKPSPRIFVLTNRHFIIVAQNLVNGQLVISAERTIPIGAIKSVSTSNLKDDWFSFVIGAQEPDPLMNCVFKTELFTHLSNALHGQLNIKIADHIEYNKKPGKLATVKVVKEPGSSNVDTYKSSTIHTSAGEPPSSVSKPTPRGKQVAARPVTKGKLLRPGGPGGGPSKLAARPMPARQPVPQPAASQAPAPQPAAVPRPVPQPVAAVAASHTRTASSGSMRAPPPPPPVSPPAPKKPMAKVLYDFSSAQSNELSIKAGELVEIVSKEGNGWWLCMNTTTSVQGWTPQAYLEEQKAAPPPPPPAAPRSTPATNGTATAAAAKAKPAPPAPPAKRPNMAGRKMAPPPPSAPRDSAVSMNSQDSSGGSGRGTPNSASNASLAGGLAEALRQRQEAMHGKQDDDDEW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex.  Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Localizes to cortical patch-like structures. Enriched at sites of polarized growth, like the growing hyphal tips and sites of septum formation (By similarity).
Protein: NFYB_BOVIN
Sequence: MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTDEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUMMR_HUMAN
Sequence: MYLRRAVSKTLALPLRAPPNPAPLGKDASLRRMSSNRFPGSSGSNMIYYLVVGVTVSAGGYYAYKTVTSDQAKHTEHKTNLKEKTKAEIHPFQGEKENVAETEKASSEAPEELIVEAEVVDAEESPSATVVVIKEASACPGHVEAAPETTAVSAETGPEVTDAAARETTEVNPETTPEVTNAALDEAVTIDNDKDTTKNETSDEYAELEEENSPAESESSAGDDLQEEASVGSEAASAQG
What is the function of this protein?
Plays a role in the trafficking of mitochondria along microtubules.  Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia.  Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion.  Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity).  Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons (By similarity).
What are the official names of this protein?
Protein MGARP, Corneal endothelium-specific protein 1, CESP-1, Hypoxia up-regulated mitochondrial movement regulator protein, Mitochondria-localized glutamic acid-rich protein, Ovary-specific acidic protein.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Mitochondrion inner membrane; Single-pass type IV membrane protein; Cytoplasmic side. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion.
Protein: PSAI_WHEAT
Sequence: MTDLNLPSIFVPLVGLVFPAIAMTSLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.