PharMolix/UniProtQA huggingface dataset:
Protein: KSB_SALMI
Sequence: MALPLSTCLLFHPKESRSRRFCFSPASASLKSGLHSATSAKIASMPTCFEQTRGRIAKLFHKDELSVSTYDTAWVAMVPSPTSLEEPCFPDCLNWLLENQCHDGSWARPHHHPLLKKDVLSSTLACILALKKWGVGEEQIKRGLHFLELNFASATDKCQITPMGFDIIFPAMLDYARGFSLNLRLDPTTFNDLMHKRDVELKRSNRNYSSETETYWAYIAEGMGELQNWESVMKYQRRNGSLFNCPSTTAAAFIALRNSDCLNYLHLALKKFGNAVSAVYPLDIYSQLCTVDNLERLGISQYFSTEIQNVLDETYRCWMQGNEEIFMDASTCALAFRTLRLNGYDVTSDPVTQILQECFSSSFRGNMTDINTTLELYRASELVLYPDERDLEKQNLRLKLLLEQELSSGLIQSCQLGRSINVEVNQAIEYPFYAIMDRVAKRKSIEHYNFDNTRILKTSYCSPNFSNEDFLFLSIEDFNRCQAAHREELGELERWVVENRLDELKFARSKSAYCYFSAAATFFAPELLDARLSWAKNGVLTTVIDDFFDVGGSVEELKNLIQLVELWDVDISTECYSHNVQIIFSALRRTICEIGDKAFKLQGRCITNHIIAIWLDLLNSMMRETEWARDNFVPTIDEYMSNAHVSFALGPIVLPALYLVGPKLSEEMVNHSEYHNLFKLMSTCGRLLNDIHGYERELKDGKLNALSLYIINHGGEVSKEAAIWEMKSWIETQRRELLRLVLEGKKSVLPKPCRELFWHMCSVVHLFYSKGDGFTSQDLIQLVNTIIHQPILLNDQTGAGLSKLHD
What is the function of this protein?
Catalyzes the conversion of ent-copalyl diphosphate to the gibberellin precursor ent-kaur-16-ene.
What are the official names of this protein?
Ent-kaur-16-ene synthase, chloroplastic, Ent-kaurene synthase, SmKS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS19_CLOBJ
Sequence: MSRSVKKGPYIQEVLLKRINEMNKNGEKKVLKTWSRSSTIFPQMIGHTIAVHDGRKHVPVYITEDMVGHKLGEFVLTRTYRGHDDKSEKSSRLR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NU2C1_BUXMI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVISITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLHLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL21_LEPCP
Sequence: MYAVIKTGGKQYKVAAGEKIKVEQIAAEVGQEIVIDQVLALGSGADLKIGTPLVEGATVTATVLAQGRHDKVRIFKMRRRKHYQKRQGHRQNFTELQISAVLG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL1_MOOTA
Sequence: MPKHGKRYREVSKLVSRQELYEPDEAIELLKKTASAKFDETVEVAVKLGVDPRHADQQVRGTVVLPNGTGKTRRVLVFAKGDKAKEAEEAGADFVGAEDLVEKIQGGWLDFDVAIATPDMMGLVGRLGRILGPRGLMPNPKAGTVTMDIARAVKEVKAGKIEFRVDKTAIIHAPIGKASFEASKLKENFQALMDALLRAKPATAKGQYLKSVSLATTMGPGIRVNPLRAVK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ARP4_GIBZE
Sequence: MAQQPLSSSAQPTDIYGGDEVSALVLDPGYCSTRAGFAGEDVPKSILPSFYGHVTGDNSRDLFGDECLIPRENYEVRNYMNKDSVVEDWDVAARIWENMLVNRLQPERQTPPSKNGLNDDPRPEGQDGEGDVAMDDAEAESMEKPLGENPLLVTEAPWNTPKAREKAIEIIMENWGCPAFWMSRTPVLAAFAAGKATSLVIDVGGANTSVTAIHDGMVLKRSIQKSPVGGIWLSSQIRSLFETSEPQVELTPTFMIENKTPVDALSSPSVRLRNFPYSITDSFRAYEEERVLTEFKESVVEVWRGPGRYSVPGNEEFVKTQPGRVFEMPDGYNQMWREQRFRVTEGMWDENAGYPIPEADRLNKTQTIPELIRAALNAVDVDLRGNLLANVVVTGSTSLINGFNDRLNTELMAMYPGLKIKIHAAGLTSERRFGAWIGGSILASLGTFHQMWISRKEYEENGPNVVEKRCK
What is the function of this protein?
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Is required for NuA4 complex integrity.  Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
What are the official names of this protein?
Actin-related protein 4, Actin-like protein ARP4, Actin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASIC4_MOUSE
Sequence: MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGISTLGLQELKEQSPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC
What is the function of this protein?
Probable cation channel with high affinity for sodium.
What are the official names of this protein?
Acid-sensing ion channel 4, ASIC4, Amiloride-sensitive cation channel 4.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COLI_MACNE
Sequence: MPRSCCSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLLECIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNSSSGSAHQKREDVAAGEDRGLLPEGGPEPRGDGAGPGPREGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELTGQRPRAGDGPDGPADDGAGPRADLEHSLLVAAEKKDEGPYRMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGQ
What is the function of this protein?
Endogenous opiate.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: HBB_MACFU
Sequence: MVHLTPEEKNAVTTLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLNHLDNLKGTFAQLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RPAB1_DICDI
Sequence: MEDINRLLQIRKTVLQMLSDREYIITAYEQEYPRESFVSRENLTMYCVKKDDPTDSIYVFFPDTPKVGVTQIKKYVDIMKDRQANRAIIVVQQNITPFAKQALAEFSQEKKITLEQFNEAELLVNITHHQLVPKHILLTKEEKLELLTRYKMKESQLPRIQTNDPVARYYGLSRGHVVKIVRPSETAGRYITYRLCV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit rpabc1, RNA polymerases I, II, and III subunit ABC1, RPB5 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AFAP1_CHICK
Sequence: MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFEIKEHVQKPEVANSLPAPPQMPLPEIPQQWLPPDNGPPPLPTSSLPEGYYEEAVPVSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKMRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKENKLLCYKSSKDQQPQMELLLNDCSITYIPKDSKKKKHELKISHQGADALVLAVQSKEQAEQWLKVIKDVCSNCTGTVDSDGPLSSSPVHKTELEKKLSSERPSSDGEGAVENGITTVCNGKEQVKRKKSSKTEAKGTVTKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGMLLAETGSSTDPGALHYDYIDVEMTASVIQAAKQTFCFMNRRVISTNPYRGSTANGYACPSGMALHYDDVPCINGSFKGKKPPATANGITGKVRTLNSQPKKPESVSCVKRTASNAEQYKYGKNRVEAVAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQVILEDKLKKLEEECKTKEAERVNLELELTEVKESLKKALAGGITLGLAIEPKSGTSSPQSPIFKHRTLENSPISSCDTSDTECSIPVNSAAALKRPPSSNNSPCRGHVLRKAKEWEMKNGT
What is the function of this protein?
Functions as an adapter molecule that links other proteins to the actin cytoskeleton.  May function in facilitating interactions between SRC and actin filaments.  May modulate changes in actin filament integrity and induce lamellipodia formation.  Can cross-link actin filaments into both network and bundle structures.
What are the official names of this protein?
Actin filament-associated protein 1, 110 kDa actin filament-associated protein, AFAP-110, Neural actin filament protein, pp110.
Protein: CAT1_STAAU
Sequence: MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRVINSNTAFRTGYNSDGELGYWDKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVEKYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNSNYLLPIITAGKFINKGNSIYLPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: RS8_MYCMS
Sequence: MTTDVIADMLTRIRNANQRYLKTVSVPSSKVKLEIARILKEEGFISNFTVEGDVKKTINIELKYQGKTRVIQGLKKISKPGLRVYAQANEIPQVLNGLGISIVSTSQGIMTGKKARLANAGGEVLAFIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS20_MESHJ
Sequence: MANIKSKIKSITKMQKARAKNNAIKSRVKTAIKKAKIAISTDASNKSDLIAKAHSEISKAKSKGVFHKNKANRKISRLNLFANTYTTPAQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UXUA_YERPY
Sequence: MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRPILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: MVP_LNYV3
Sequence: MLDVNSVRKHVLKTGSLTSAVGTGTIYQGTYNRYAKKKELNIIVTSSGSNNVIMRQVPLFDKEDLDAMKSDTTSNKYLHIGCITVSIEPLLHQRYMKNFGKTIAGNCAIIDSTFRKVDQSIISLHKYDLSRGRADYVSYPNHCLSLTDPMIQKRLSVLLGIKGIDVEPGVELFSICIGYIVSSVNTLHPVSQLGIQGVAINGTESADIDELGAEDIDQLSLSYNDSKIISLPSDEDIYYRSKGSLFSKGRTIKRRTMRTRVPDPEEPIKLTKSQSSRIEHGKVMRLLKNKQIREKIERGMIA
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity).
What are the official names of this protein?
Probable movement protein 4b, MP, Cell-to-cell transport protein, Protein 4b.
Protein: AT131_HUMAN
Sequence: MAAAAAVGNAVPCGARPCGVRPDGQPKPGPQPRALLAAGPALIANGDELVAAVWPYRRLALLRRLTVLPFAGLLYPAWLGAAAAGCWGWGSSWVQIPEAALLVLATICLAHALTVLSGHWSVHAHCALTCTPEYDPSKATFVKVVPTPNNGSTELVALHRNEGEDGLEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSPTLSNSGIRATSRTAKQRSGLPPSEEQPTSQRDRLSQVLRDLEDESTPIVKLGDASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQGLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFVHFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIAQVLLLDFCLALLADRVLQFFLGTPKLKVPS
What is the function of this protein?
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum (PubMed:32973005, PubMed:36264797).  Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane (PubMed:32973005).  Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains (PubMed:32973005).
What are the official names of this protein?
Endoplasmic reticulum transmembrane helix translocase, Endoplasmic reticulum P5A-ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYM_BORGP
Sequence: MKKMNLVTAALPYVNNIPHLGNLVQVLSADAFARYSKMSGIETLYICGTDEYGTATETKALIEKTSPLELCNKYYKIHKSIYKWFNIEFDIFGRTTNKHHQDIVQNFFLKLEKNGYIKERETEQFFCNKDSIFLADRYVIGECPECQSIAKGDQCENCSKLLNPIDLINPKCIICKNKPVLKKTNHLYIDLPKIKRKLEKWIKNSTTSKNWNTNALKMTNAFLRDGLKERAITRDLKWGIPVPKKGYENKVFYVWFDAPIGYISITKNLVKNWESWWKNNEQVNLVQFIGKDNILFHTVIFPSIEIGSKENWTILNQLSSSEYLNYENLKFSKSEGTGIFGNDVITTGIPSDVWRFYIYYNRPEKSDFQFMWQDLMERVNTELIDNFSNLVNRVLTFQKKFFGDVIETIEIQNKFWKQIIPKYNKILNLFKKTELKSALKEILKISSLGNKIFQDNEPWKRKDSSPQETKELISNLIYLIRDLSILMMPFIPETSKKIQQFFGNSYQFSTKILGTKSGIKRIEFTEILFNKLEQKKINNLKLKYSGEKNMEEKEQPENLFREKVLLKVVKINKIERNPEAKNLFILKLDDGTNENKQIVSSLEGYYTEKELLGKHIIIVDNLKPAKFRGIKSEGMLIAAEDKNKNFKIIIVEDSIKNPIPGERIILENDQNKDLICPPKIDINKFSKANIVAKDGELKINGINLILEHSKNKILSKDIPNGIVC
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_BACVZ
Sequence: MKTKKQQYVTIKGTKNGLTLHLDDACSFDELLDGLQNMLSIEQYTDGKGQKISVHIKLGHRYLYQEQAEKLTDLIASKKDLVVHSIDSEVIAKEEAQRMKEEQEIVSVSKIVRSGQVLHVTGDLLLIGDVNPGGTIRAGGNIFVLGSLKGIAHAGYNGNNRAVIAASEMMPTQLRINHVLNRSPDHIQKGNDMECAYLDTDGNMVIERLQQLAHLRPDLTRLEGGM
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PYRE_ECOLC
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RUVB_CHLFF
Sequence: MTHQVSVLHQDKKFDIALRPKGLREFCGQAQLTERLELFLSAALQRGEVPGHCLFFGPPGLGKTSLAHIVARTVGKGLVVASGPQLVKPSDLLGLLTSLQEGDVFFIDEIHRMGKVAEEYLYSAMEDYKIDITIDSGPGARSISVDLAPFSLVGATTRSGMLSEPLRARFSFSGRVSYYSDEDLATILKRSSNLLGIDADAAALYEIARRSRGTPRLANNLLRWVRDFAQMREGNRINSDVAEKALSMLLIDDWGLNEIDIKLLTTIIDYYQGGPVGIKTLSVAVGEDIKTLEDVYEPFLILKGLLKKTSRGRMVTQLAYNHLKRCSDNLQILGEEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MET16_DROPS
Sequence: MVRNKKNKYAMHPRNILRVPPDYTKLAIKYRDFRQVCELELTGKVSVNFRNEKTLRELSKMLLKEYFELDVDFAPGSLVPTLALRLNYILWLEDMLLPLNLETVRGIDVGCGSSCIYSLLGAKKNGWNMLALESKEENIDYARENVRRNNLEDLIEVYAQPDKSNIFKSYFETEKLRKEFHFCLCNPPFFDSNSPNPFGGNTRNPQRRPAPNNVRTGSAEELTCEGGEVHFVQRIIEESQLNKQRVLIFTSMLGVKASVPKILDYLKERQITNVTTTEFHQGHTTRWAVAWSHQPTPLSPGTQCN
What is the function of this protein?
RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA).
What are the official names of this protein?
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
Protein: SGPL_LEGPL
Sequence: MFGFISDLLTAAVSSLDELLQDTPAHQIILGTAALYFLYNQYHNPSISRWYLSRNNASMKQRIIDSAYALAKNLPGVNQIIEKELNKELSSTREKLRIQRSGMTLREEIPEEGLSPQDILSAFDVDVEKCHFDFLSVNNDSPEREFLVGGGDGKDSGALYAIHPKELTELLKEVYGATALTNPLHDKWPRINAMQAEVIRWCQNLFHGSKEGYGLLTHGGTTSIIEAMAAYVIRARAKGIDYPEIVVPETAHAAFKKAAELTGAILITVPVDKKTGAVNPRVMSSYITRNTAVIVGSAPSFMNGIHDPVSELGQLAKKKNVPFHVDACLGGFLTAFLDTSSEPMDFRVPGVTSISADLHKYGCCPKGTSVCLFSEDSPALSVYAALNWSGGLYATPGILDGSTSGARVAEVYATLSYYGKNKYQEIAKSIIKLRNAIQKELTALVEEGNGLTSEDIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVRGFETQFIKDLREAVIDVKNYPPGKKASGNVKVYGAVGMMPIELQKEICKQYQKARLDFTAASHGSLGIFTTSPTEEDDGLRNRKVGEQKVQTSL
What is the function of this protein?
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine (By similarity).  Possibly implicated in influencing the macrophage autophagy pathway.
What are the official names of this protein?
Probable sphingosine-1-phosphate lyase, S1PL, SP-lyase, SPL, Sphingosine-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
Protein: CA2D1_RABIT
Sequence: MAAGRPLAWTLTLWQAWLILIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVHQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQRIKPVFIDDANFRRQVSYQHAAVHIPTDIYEGSTIVLNELNWTSALDDVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPNVQNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSSLALVLPTYSFYYIKAKIEETITQARYSETLKPDNFEESGYTFLAPRDYCSDLKPSDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSIADILQIGWWATAAAWSILQQFLLSLTFPRLLEAADMEDDDFTASMSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHVEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIIGIQFVLLWLVSGSRHCLL
What is the function of this protein?
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (By similarity).  Plays an important role in excitation-contraction coupling (By similarity).
What are the official names of this protein?
Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-gated calcium channel subunit alpha-2/delta-1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel subunit alpha-2/delta family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: E310_ADE07
Sequence: MIPRNFFFTILICAFNVCATFTAVATASPDCIGPFASYALFAFVTCICVCSIVCLVINFFQLVDWIFVRIAYLRHHPEYRNQNVAALLRLI
What is the function of this protein?
Down-regulates the EGF receptor.
What are the official names of this protein?
Early E3B 10.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3B family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.