PharMolix/UniProtQA huggingface dataset:
Protein: SRE30_CAEEL
Sequence: MIIHISNSSSYIWLSVYFYKEPLSLKLLISIFELSSCILCGYILNLSIFVMLKIQLFHKNLMFLTVPLFAIWHELIIGKFITIAYRLKIVNPGFELGEHTVFWTNDPDKTLEVAGSSGLELLIFGGFLQWHTIYSIVFGILAVATERTIASVYIKDYESKERIYIPIILTIISQLLSISISLAIITQSIGPFLARLPFVICAPLSVLVFLFIKHTNQSLLKEICNPKRTRIFTVSQQCQVKENLRALRLGTRLVVVVIFYISICGFGIAALTFGLIPAGFGHLIENFLFLHPYPICLTAMFSIPQWRDQFKKSILPFLNRRLAKIEQVVTVRIEVNVQNSSSVETDIYFRQLTESWT
What are the official names of this protein?
Serpentine receptor class epsilon-30, Protein sre-30.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sre family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEUD_LACLA
Sequence: MEKFTIYKGTSVPVMNDNIDTDQIIPKQFLKAIDKKGFGKNLFYEWRYLKDYDENPDFILNAPKYKKASLLISGDNFGSGSSREHAAWALSDYGFRAIIAGSYSDIFYNNALKNGLLPIKQPREVLNQLTKLSSQEEITIDLPHQLIITSLGDFHFEIDPIWKDKLINGLDDIGITLQYEEAISAYEQKNQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PRM7_YEAS7
Sequence: MYRTRSSDEVATLTDPTSSSDVATSADPTSSSAVTTLVDPTTSVVISTSVDQTSSSDVATSVDPTTSVISSTSADPTTSADSTTSTVQTTSVDPTSSVVSSSSADLSSSVISSSSADPTTSTVQTTSVDPTSSVVSSSSADLSSSVISSSSADPTTSTVQTTSVDPTSSVVSSAPVDPASSVVSLTSSYPTSSSTVTISANSNGSATLTAQTTSIDPVSSIVSSSGATTIISSASIDPASSVVSSTSSEPTSFIVSSTSVYSTRPSGPTTSTDLATFSDTIILRVSTTSTSQDTQTVSSSLTDMVSSTGSADLSVSSIQRSQVDPSTFAVSNSPVYPTASTGSTSTGIPIASESLSLSRQQGISATSSSSIVTLTPVDSASSSRSSATSIIKPNMPVSSNDSKTQSSVSVVDTFQSTKSSYPSITSADPTTLASENGLVGSSSSAHPITLDRTYASAHASVTDIVSRVTDSTRHTTLVTSNINIQSEVGNLNYSGPKDTTITKQSAFMTSPASTSTISNVQSTASVMNHSIEDNISATASLESVSGTSTKDYSSQSSAIHYTNSFTTTTTNAFITSKHSIAAVSTGAITSSASISLIMEGSANIEAVGKLVWLAAALPLAFI
What are the official names of this protein?
Pheromone-regulated protein PRM7.
Protein: RL34_SALAR
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: FAR7_LUCCU
Sequence: QANQDFMRF
What are the official names of this protein?
FMRFamide-7, LucFMRFamide-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGA_STRE4
Sequence: MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLERLGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFEIFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVAKTFVAERKKLGFPLLDDASRVALLAED
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC4CH_SALPC
Sequence: MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDVLRVGRFEDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: SYH_CHLT2
Sequence: MSNALPKGVFDIFPYVTSPKNLWRNSSLWKRVEHAAHRICNLYGFDEIRTPVFEKTETFLRVGEHSDIVKKEVYTFLDKKGRSLTLRPEGTAAVVRALLDHSADMRKDNKFYYILPMFRYERQQSGRYRQHHQFGLEAIGVRHPLRDAEVLSLLWDFYAAVGLQHMQIHVNFLGGQKTRARYDEALREFFRKDLDRLSPLSQERYHANLLRILDSKEPEDQEFIEKAPSILDYIDDRDLSYFDAVLAQLKALGIPFAINPRLVRGLDYYTDLVFEAVTVVGERSYALGGGGRYDELVAQSGGPSMPAFGFGVGLERVIQTLLEQGNSLSTSTRRLRLIPMDEQADAFCFSWANRLRNLGIATEVDWSHKKPKLSLKDAADQQVSFVCLLGEQELATKQFIVKDMSLHQSFSGAQQDVEQRLVYEVQNA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_STAS1
Sequence: MTEQNESAFNENEEVNEETSQTDSVENNDETTETSQDNLQEDDSQEIAEDVDPKDEEIQQLKKDVQENEEKYLRLYAEFENYKRRIQKENQTMKAYKAQDVLNDILPTIDNIERALQIDGEDEQFKSLKKGVEMVHESLLNALKNNGLEKIETEGQQFDPNVHQAVVQDDNPDFESGQITQELQSGYKLKERVLRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_STRAZ
Sequence: MPSQPPADFTDFKVADLSLAAFGRKEITLAEHEMPGLMSIREEYAAAQPLAGARITGSLHMTVQTAVLIETLVALGADVRWVSCNIYSTQDHAAAAIAAAGIPVFAWKGETLEEYWWCTEQALTWPGHTGPNMILDDGGDATLLVHKGVEYRKTGILPEAENEELAVVRALLDRSGLDWTAMSSEIRGVTEETTTGVHRLYEMHRDGTLLFPAINVNDAVTKSKFDNKYGCRHSLIDGINRATDVLIGGKTAVVCGYGDVGKGCAESLRGQGARVIITEIDPICALQAAMDGYQVATLDEVVDKADIFVTTTGNKDIIMASDMAKMKHQAIVGNIGHFDNEIDMAGLAQIPGIVKDEVKPQVHTWKFPDGKVLIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPDEYPTDVYVLPKHLDEKVARLHLDALGVKLTTLRPEQASYIGVEVDGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TE2IP_RAT
Sequence: MAEVMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRRLSTLILHGGGILCRVQKPGAVLLAQPGEALAEASGDFISTQYILDCVERNEKLELEAYRLGLTEQASDPKPGASAEGSTEPEPQPLTGRIAYTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLQGQEHKYLLGNAPVSPSSQKLKRKAEQDPEAADSGEPQNKRTPDLPEEECVKGETKENGEADNKLFEEATPELGEAVVDESPDFEIHITMCDGDPPTPEEDSETQPDEEEEEPKVSTQEVGTAIKIIRQLMEKFNLDLSTVTQALLKNSGELEATSSFLESGRRPDGFPIWCRQDDLDLQKDDDDTRNALVKKYGAQNVARRIEFRKK
What is the function of this protein?
Acts both as a regulator of telomere function and as a transcription regulator.  Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome).  In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair.  Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.  Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2.  Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression.  When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes (By similarity).
What are the official names of this protein?
Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric protein 1, Repressor/activator protein 1 homolog, RAP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RAP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Chromosome, telomere. Note=Associates with chromosomes, both at telomeres and in extratelomeric sites. Also exists as a cytoplasmic form, where it associates with the IKK complex.
Protein: ICO5D_LIMDO
Sequence: LRLSLYFPISISLSLSLEAMASFIATTTPAMPAFASVLDPKIPTKPEPKTETPKPKDDLERFRTSEVVLERKAKGFWRRKWNPRDIQNAVTLLVLHALAAMAPFYFSWDAFWISFILLGFASGVLGITLCFHRCLTHGGFKLPKLVEYFFAYCGSLALQGDPMEWVSNHRYHHQFVDTERDVHSPTQGFWFCHIGWVLDKDLFVEKRGGRRNNVNDLKKQAFYRFLQKTYMYHQLALIALLYYVGGFPYIVWGMGFRLVFMFHSTFAINSVCHKWGGRPWNTGDLSTNNMFVALCAFGEGWHNNHHAFEQSARHGLEWWEIDVTWYVIRTLQAIGLATNVKLPTEAQKQKLKAKSA
What is the function of this protein?
Desaturase involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp.  seed oil.  Only acts on saturated fatty acids.
What are the official names of this protein?
Icosanoyl-CoA 5-desaturase, Delta(5) acyl-CoA desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CARB_STAS1
Sequence: MPKRQDIETILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSNPATIMTDNEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQLHDSGELEANNVKLLGTELESIQQAEDRELFRTLMNDLGVPVPESDIVNTVEQAFAFKEEVGYPLIVRPAFTMGGTGGGICHNDAEFKEIVTNGLHYSPATQCLIEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPHSLDYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAIGLTLDEMLNPITETSYAAFEPTLDYVISKIPRFPFDKFEKGERVLGTQMKATGEVMAIGRTYEESLLKAIRSLEYGVHHLGLPNGETFDLGYIKERIQDQDDERLFFIGEAIRRGTTLEEIHEMTKIDYFFLNKFQHIIDIEHDLKSNKGDIDYLKFAKNYGFSDRVIAHRFDMTEEEVYDLRQQNGIIPVYKMVDTCAAEFESATPYYYGTYEYENESVVTEKEKILVLGSGPIRIGQGVEFDYATVHAVWAIQQAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIIDLEQPKGVVVQFGGQTAINLADKLAKHDVKILGTSLEDLNRAEDRKEFEALLHTIDVPQPNGKTATSPQEALENARSIGYPVVVRPSYVLGGRAMEIVNSDAELEDYMNQAVKASPDHPVLVDRYLTGKEIEVDAISDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLKQEEMTTLEDFTIRLAKGLNIVGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITNIQMAQLAMRAIIGDKLVDLGYQPGIQPYTEGVFVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKDATMEKALFKGLTASGMEVKDHGTVLMTVSDKDKDEIVSIAQRLNEVGYRILATQGTARKLAENNIPSEVVGKIGGEDDLLTRIQNGEVQIVVNTMTKGKEFERDGFQIRRASVENGVPCLTSLDTVVALTRVIESMTFTMKNM
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RS8E_METMJ
Sequence: MQWQGRSVRKPSGGRYHTSQGKKRTEIGRAPAETHIGEERRRIVRTFGGNQKVRALRLEYATVSNPATGETKKTKIEAVEANSADPNYVRRKLLTKGAIIKTEMGRARIVSRPSQDGVVNAVLLA
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: MOT1_CHLRE
Sequence: MALQNAWQNTKERARETWAQLTWSEVSGSLGDLGTFLPLLIGLVQKVHLDLGTTLTITGLYNIISGWQFRIPMCVQPMKTIAAVALAGGAAGLDLPQLLHAGLFVAGCVGLLGASQAIDLFNWLVPPPVIRGVQLAVGVKLAMKGVDMALRLHGGPSSGWRPWLGTEGLVVGAVALAAMIATTLPPRAARRGTLEAADEGGLGPRPTDTAFEPLLRRLPACCGGGDRAPQVEGAAVSAERAGLLAHAEGGERSGNLDDGTEAGVGAAAGGGGCGGGGGGGRIPSALIAVVVGLAMAVLHRPGLVWELRLGPTLPRLLRPSWPDFKTGALRGGLPQLPLTTLNSVIAVTQLANALFGDKPEAERRRWRPSAVALSVALLNGAGVWLGAMPCCHGAGGLAAQYKFGARTGHAPILLGCIKAALGLLFGGSLVVLLEAFPQPLLGALLTVSGIELASVVRHTRSPRGYTFALLTAVAILALDNTGTGFLVGLVGVAAVAAYEGAVAAAAARWPRVFARGGRA
What is the function of this protein?
High affinity molybdate transporter.  Acts through an energy-dependent process.
What are the official names of this protein?
Molybdate transporter 1.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SIX3F_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWGWGLACWCEGLPADREWDYETDTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3f.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NLTP_MACIN
Sequence: MANSGVMKLVCLVLACMVVAAPLAEAAITCGQVVSKLAPCLTYLRSGGAVPGTCCNAVKNLNNSAKTTPDRQTACGCLKNAYNSISGINAAYAGGLPAKCGVNLPYKISPSINCATYTLSLYNF
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP, NsLTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: CFA70_CHLRE
Sequence: MAPKKKEDKDAPPPEDTNPYGVFVSVTMPSATVVLDVQDDAAAQRETHITLNIPGCHVPWASAHTAPSEGGVYQYSVVKHFRRSGGQDGLLQLINGVLTVTVNDSATNAVLASATVDQLQGFAIGQNTWSTEGLDLVPAAEVPEGVPKARSARLAFASIALQERPLPEGADAAALAAAPPPPEAELPPLLPYSYVSGEAAEKGNMVELVVSGLSPLPPNLQAAADAAGGKLHVTVGLALPGGGPAVAVSLAVAGGRVAAPAFRRELLPPGCLQALQYALEDGLPVVLEVARYVSAEGMADPAFEGYHAAAAAPALAAGLGAAGATEAAAEGLSLTAWAASGAKTCLPPYTAPAGKPKPVEAEVPPAGTCLWEKAGAQLAVSLRFARPVVPAWRPPPPPPRPLLELIPPRDLTPKPPPTTAVDEFKAKVRVIARALAEEYKAVLPPPDASVAAAAAGGGAEGRHKALIFELNRSGKYAQMRDSLKTAVVSLVREKYRKSGSMSPNEMALLYNDLYGSLLAAVHSSLNDLVDAAAARPRAPPPAPVPDKQRLGELLELAAQAEAMGDTDRAELLHQRRLLAKNDAQVWYEYGTYCLRRGGAKRGRAEECFREALALEPAHRGALLALLGCSVAAGRNTDPAYLESAEAAAHRLLDVAGRSSLDAWAALAVVYRAYGEAKRAELASCEQEMARLEKQQLAAAAAAASAGVSPSPSYGEGRAGGNGGGVPATEPSTASAGSVAGSAGELQARSFISLANTLLESLALPAEAALALELAAGLRHWPSVGPDTRTLHALAGALAEQALARAAGGGAASAAAEAMLTPGSSVLSMMRADAGEAVSSVAAEAAWRCRLLVAQLHKARGATDEAIRFYQSFIAITQQHAPSTPPPPPPPPPPPPPPPPQEYIEAARSSGRLAEVPLSAWLELAEAYAARGQARFAADVFLLGASARPGCAVLWRGAGRCFVGAEELGPADMALSEANVLDPEDPEAWGWLALVALREGRAEDAEKALAFGLRCGLGDPGLLLDIAAEYRAAGQRRAEQRVLQEVAVKLMPESCSARLLLARCLVAQRCGAEAAEAVAAARQLAAHEDDEAAVAELEAELRGMA
What is the function of this protein?
Axoneme-binding protein that acts as a regulatory componement of the outer dynein arm and regulates ciliary motility.
What are the official names of this protein?
Cilia- and flagella-associated protein 70, Flagellum-associated protein 70.
What is the protein family that this protein belongs to?
Belongs to the CFAP70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium. Note=Localizes at the base of outer dynein arms.
Protein: RL22_CUPTR
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPIERALNVLTFSPKKAAGIVKKVVESAIANAEHNEGADIDELKVKSIYVDKATSLKRFTARAKGRGNRIEKQTCHITVTLGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: VLTF3_VAR67
Sequence: MNLRLCSGCRHNGIVSEQGYEYCIFCESVFQKCTKVQKKSNFHVSNKLIHLRNVLRRLLSHQCSGEIISELLDIMEKNQISTDDVDANFVSSFLKANERINKKDYKLVFEIINQVKDEKLNLSTEKINEVVEIFKHLVFFCQENTPSKTINYSFFLDKIFDITSVTKNLKPQTVKNYTKNNSNQLVWENFLAHMRSKKRVTMVEDYGHEYVFVDERFSTCSLEV
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Viral late gene transcription factor 3, VLTF-3, Trans-activator protein A2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus VLTF-3/OPG127 family.
Protein: NADE_FINM2
Sequence: MNYAKLCEDLTKWIKEEVESANLKGAVFGISGGIDSAVLACLCKKAFGDNALGLIMPIKSNPKDEEDARILAKSIGLRFTKVDLNESYDALIGTFEKNSVEMAASNIKPRLRMITLYYYAQNNGYMVLSGSNRSEFMTGYFTKYGDSGADLMPLLNLYKTDIFEMAKVLGVPDVIINKKPSAGLWEGQTDEDEFGFTYEELDDYLMNNSNTKSKDLIDKKIKQSEHKRKFAKSFEFDRRNY
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CP52M_DEBHN
Sequence: MSELLDSIQPYLTKWYVVISALLVSFFIAHKISVARFKATHNCAASPEYYKVNWFSLPLLYRLIQVKREGRLLDFAQKIYDDVKALTFVIKIVGVPVIITRDPENMKAVLATQFNDFALGTRHAHFKPLLGDGIFTLDGNGWKQSRSMLRPQFSREQVAHVQALEPHLQRLAKHIRLADGETINIQDLFFKLTVDTATEFLFGQSVYSLKDAAINDPPTEDFDGRSSFANSFNTAQTYLGTRAYLQMFYFIVNNSDFRKCCKQVHDFTRFYVQKGLDMTPEELEKKSENGYVFLYELVKQTRDPKVLQDQLLNILLAGRDTTAGLLSFTFFELARHPRVFNKLKEEIYEAFGKGDDARVSEITFESLKKCEYLKWVMNEMLRLYPSVPVNFRVATKRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERWAESRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMFDKLELHDDRPYPPAKSVHLTMCHQDGVYVSLS
What is the function of this protein?
Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids.
What are the official names of this protein?
Cytochrome P450 52A13, Alkane hydroxylase 2, Alkane-inducible p450alk 2, DH-ALK2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: RL11_CUPTR
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQGMEPGLPVPVVITAFADKSFTFVMKSPPATVLIKKAAGITKGSPKPHTDKVGKITRAQAEEIAKAKNADLTAADLDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RUVB_VIBC3
Sequence: MIEADRLIAPISNHFKDEEVIDRAIRPKKLADYQGQDHVRDQMEIFIQAAQMRQEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEYYKVADLQHIVQRSAQCLGLSMDSEGALEVARRARGTPRIVNRLLRRVRDYAEVKGDGHICAQTADRALNMLDVDHQGFDYMDRKLLLAIMEKFSGGPVGIDNLAAAIGEEKDTIEDVLEPFLIQQGYLQRTPRGRIATDRAYLHFGIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CRCB_STUS1
Sequence: MIRMAFAVACGGVIGTLLRFALATWVSAQWPRHFYLATVAVNLLGCLLIGYLYATFLARPDISPELRGALIIGFLGALTTFSSFSLDALRLLESGQLATAFAYVGGSVLGGLLAAWAGLALARL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
Protein: DMR17_CRYX8
Sequence: MSKQPASEDIFGCQAALYEWAESYDSKDWDRLSKCIAPVLRVDYRAFLNQLWEAMPAPEFVGMVSNERFLGNQRLKTQHFVGGASKWVQTSESEITGYHQMRVAHQKYADDALTEVALKGHGHGKATIWYRKVDGEWKFAGLEPGDRWGEFDYDKIFLHE
What is the function of this protein?
Scytalone dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
Scytalone dehydratase-like protein dmxR17, Dimeric xanthone biosynthesis cluster protein R17.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.