PharMolix/UniProtQA huggingface dataset:
Protein: RRT14_YEAS1
Sequence: MSSSLSQTSKYQATSVVNGLLSNLLPGVPKIRANNGKTSVNNGSKAQLIDRNLKKRVQLQNRDVHKIKKKCKLVKKKQVKKHKLDKEQLEQLAKHQVLKKHQQEGTLTDHERKYLNKLIKRNSQNLRSWDLEEEVRDELEDIQQSILKDTVSTANTDRSKRRRFKRKQFKEDIKGSDFVKDHRYPGLTPGLAPVGLSDEEDSSEED
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PA2B3_BOTMA
Sequence: DLWQWGQMILKETGKLPFSYYTAYGCYCGWGGRGGKPKADTDRCCFVHDC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that causes irreversible neuromuscular blockade in chick biventer cervicis muscle preparations.  The neuromuscular blockade is mediated by inhibitory action at the presynaptic motor nerve endings.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Bmaj-9, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YR699_MIMIV
Sequence: MEQSNNDDNLLVLGIGISVHKTDGVLRFEKYCQAHNLQYMIVGEGKKWNGGNLESEAGGGQKINELLIALESIKDNKLIVVCDTYDLIPLSGPEEILRKYRFLTPDNKVVFSSELYCWPDASLVERYPKVDTKYKYLNSGAFMGYRDDIYEMIKNGVKDRDDDQLFFSIKFIETDKIVLDYKCELFQAMYRCNSDLVVHKNRIFNGYTNSYPVFAHGNGPAKKLLNHMEGYFMTEPIDGSSNTINTFKLDNEPKVFFALYVDSNDLSALKQFLGKVASIQYGNKVIYLYDRSDNEQNRKLIQISYPNYHTGVTKYVFDDFKKSDAQFYFLLEQNCIITKKDILHELIMQVKDNHRVISPMIGYEQNSTRTNFWGDIEDGYYKRSENYLDLAKHKVRGLWNVPYVYGVILMHESVVRNWDLSMVKYNDKDMDLCFSLRKHTIFMYMINNNNYGYMV
What are the official names of this protein?
Uncharacterized protein R699.
Protein: CINA_ALKCK
Sequence: MNAEIMAVGSELLLGQIANTNGQFISKQLASIGVDVYRHTVVGDNEDRLKIALQEAYERADLVILTGGLGPTKDDLTKETVAAFCGKRLVYDENALHEIEDYFKRHNRVMTPNNKKQAYVIEGCTVLANRHGMAPGMLCELEDGKKLALLPGPPSEMKPMFVNELLPKLLGATEQTEITSRVLHFFGIGESQLETDLLDLIATQTNPTIAPLAGDGEVKLRLTVKHADKNEAARLLDETETLIRKRVGSYLYGYNETTLVKETFLRLQASGLTIASAESLTAGLFSSELAAFAGASHVLKGSVTAYSNELKQQLLQVSSATLASDGAISEACALEMARGVKTLYGSDIAISFTGVAGPGVQEGHEAGTVFLALLLPGGKERVYTLSLSGGRNAVRMRAVKFGYFYLLEELKRSNGSK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: LALB2_HORSE
Sequence: KQFTKCQLSQVLKSMDGYKGVTLPEWICTIFHNSGYDTQTIVKNNGKTEYGLFEINNKMWCRDNQILPSRNICGISCNKFLDDDLTDDVMCAKKDLDSEGIDYWLAHKPLCSEKLEQWLCEEL
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin B/C, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_YERPS
Sequence: MPELPEVETSRRGIEPYLVGQTILYAVVRNARLRWPVSDEILTLSDQPVLSVQRRAKYLLLELPKGWIIIHLGMSGSLRVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWAKDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLFAAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVYGRAGEPCRQCGHPIEIAKHGQRSTFFCRHCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: FETA_PANTR
Sequence: MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEINLTDLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSAGCLENQLPAFLEELCREKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPFFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHETTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAALGV
What is the function of this protein?
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
What are the official names of this protein?
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: TXLA3_CYRSC
Sequence: MKTSMFLTLTGLVLLFVVCYASESEEKDFPKELLSSIFAADSDFKVEERGCLGDKCDYNNGCCSGYVCSRTWKWCVLAGPWRR
What is the function of this protein?
Agglutinates erythrocytes.
What are the official names of this protein?
U5-theraphotoxin-Hs1a 3, U5-TRTX-Hs1a, Lectin SHL-Ia3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_SERP5
Sequence: MSKQLKPVAPKQPIVLGKMGSTYGIRGWLRVFSSTENAESIFDYQPWLIQRSGQWQFVELEDWKRHSQDLIIKVKGIDDRDAANLLTNCEIVVDSEQLPPLEGDDYYWKDLMGCQVVTTSGYELGKVIDMMETGSNDVMVVRANLKDAFGMKERLVPFLHGQVIKKVDLTARVIEADWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDE_HUMAN
Sequence: MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
What is the function of this protein?
(Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus (VZV).
What are the official names of this protein?
Insulin-degrading enzyme, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Secreted. Note=Present at the cell surface of neuron cells. The membrane- associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
Protein: ARF2_MOUSE
Sequence: MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK
What is the function of this protein?
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.  Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: UPPP_SULNB
Sequence: MDIIQAIIIGIIEGFTEFLPISSTGHMIVASKFLGVAETDLTKAYEVIIQFAAILAVMLIYREKITFKKIDLWMKLLFAFLPLAIVGFIFKDQVKALFNVQVVAWMFIIGGIIFLIVEYYYKEQAWHVKDVEKVSWTQAWWVGFAQIFSLIPGTSRAGATIIGGLLAGLDRKTSAEFSFLLAIPVMAVVSGYDLLKHYQDFADANWGAFLIGFIVAFIVAYATIKLFLVFLQRFTFVAFGIYRIIFGIFLLMIL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLB_PSEDC
Sequence: MHSSIVLAIVLFVAIASASKTRELCMKSLEHAKVGTSKEAKQDGIDLYKHMFEHYPAMKKYFKHRENYTPADVQKDPFFIKQGQNILLACHVLCATYDDRETFDAYVGELMARHERDHVKIPNDVWNHFWEHFIEFLGSKTTLDEPTKHAWQEIGKEFSHEISHHGRHSVRDHCMNSLEYIAIGDKEHQKQNGIDLYKHMFEHYPHMRKAFKGRENFTKEDVQKDAFFVKQGHKILLALRMLCSSYDDEPTFDYFVDALMDRHIKDDIHLPQEQWHEFWKLFAEYLNEKSHQHLTEAEKHAWSTIGEDFAHEADKHAKAEKDHHEGEHKEEHH
What are the official names of this protein?
Extracellular globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RR16_SOLBU
Sequence: MVKLRLKRCGRKQRAVYRIVAIDVRSRREGKDLQKVGFYDPIKNQTYLNVPAILYFLEKGAQPTETVQDILKKAEVFKELRLNQPKFN
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TBA2_ARATH
Sequence: MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTVGGGDDAFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSILLDNEAIYDICRRSLSIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAFHEQLSVAEITNSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVGTIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTSVAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAEGGDDEDDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AL1B1_BOVIN
Sequence: PRLFALHHSATQYFSAAALPSPIPNPDIPDNQLFISNKWHDAVSKKTFPTVSPATGEVIGHVAEGDWADVDLAAKAARAAFRLGSPWRWMDALKRGWLLNHLADLVERDCVYLASLESLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWHGKTIPMDGEHFCFTRHEPVGVCCQIIPWNFPLVMQSWKLALALAMGNTVVTKVAEQTPFSALYLASLIKEVGLPPGLVNIVTGYGPTAGAAIAHHMDIGKVAFTGSTKVGHLIQKAAGNSSLKRVTLELGGKSLSIVLADADMDHAVEQRQEALFFNMGQCCCPGSWTFIEESIYDEFLERTVEKAKQRRVGNPFDLDTQQGPQVDRERFERILGYIQLGQKEGAKLLCGGEHFRQQCFFIKPTVFGGVQDDMRIAREEIFGPVQPLFKFKKIEEVIERADNTRYGLAAAVFTQDLDKAMYFTQALQTGTVWVNTYNVVTCHTPLGGFKEPGNGRELGEDGLKAYTEVKTVTIKVPQKNS
What is the function of this protein?
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde.  They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.  In the cornea, this enzyme may help in the absorption of the damaging UV-B, as well as in the detoxification of the UV-induced peroxidic aldehydes.
What are the official names of this protein?
Aldehyde dehydrogenase X, mitochondrial, ALDH class 2, ALDHX, Aldehyde dehydrogenase family 1 member B1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HUTH_SALPC
Sequence: MNTMTLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVNDIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMVLKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGEGKARWQGEWLPAQTALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFASAVVCGALTTEAVLGSRRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHKVQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFADAGEVISGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGIIAVEWLAACQGIDLREGLTSSPLLEQARQTLRERVAHYTQDRFFAPDIECATALLAQGALQRLVPDFM
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRK7_ARATH
Sequence: MSSLFPFIFLFLFSFLTSFRASAQDPRFLAYYCPNATTYSSNSTYLTNLKTLLSSLSSRNASYSTGFQNATVGQALDRVTGLFLCRGDVSPEVCRNCVTFAVNNTFSRCPNQREAVFYYEECILRYSHKNILSTAITNEGEFILRNPNHISPIQNQINQFTNLVLSNMNQIAIEAADNPRKFSTIKTELTALQTFYGLVQCTPDLSRQNCMNCLTSSINRMPFSRIGARQFWPSCNSRYELYDFYNETAIGTPPPPLPPLASPSLSDKSGNSNVVVVAVVVPIIVAVLIFIAGYCFFAKRAKKTYGTTPALDEDDKTTIESLQLDYRAIQAATNDFSENNKIGRGGFGDVYKGTFSNGTEVAVKRLSKTSEQGDTEFKNEVVVVANLRHKNLVRILGFSIEREERILVYEYVENKSLDNFLFDPAKKGQLYWTQRYHIIGGIARGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGMDQTQQNTSRIVGTYGYMSPEYAMRGQFSMKSDVYSFGVLVLEIISGRKNNSFIETDDAQDLVTHAWRLWRNGTALDLVDPFIADSCRKSEVVRCTHIGLLCVQEDPVKRPAMSTISVMLTSNTMALPAPQQPGFFVRSRPGTNRLDSDQSTTNKSVTVSIDDKSMSDLDPR
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 7, Cysteine-rich RLK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: 1102L_ASFWA
Sequence: MRFFSYLGLLLAGLVSLQGFSTDNPLEEELRYWCQYVKNCRFCWACQDGLCKNKVLKDMPSVQEHSYPMEHCMIHRQCKYIRDGPIFQAECTMQTCDATHLINA
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-2L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: RNPH_XANC8
Sequence: MSFSRPSGRTADQLRPVRIERAFTRHAEGSVLVSFGDTRVLCTASVENRVPNFLRGKGEGWVTAEYGMLPRSTHTRSDREAARGKQGGRTLEIQRLIGRALRACVDRNALGERTITLDCDVLQADGGTRTAAITGAYVALADAVNLLLKRGDIKKHPLIGAVAAVSVGIYRGEPVLDLDYPEDSDCDTDMNVVMNDGGGFIELQGTAEGHAFRRDELNALLALAEKGVGELFELQRAALAG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: NSP5_ROTSH
Sequence: MSLSIDVTSLPSIPSTIYKNESSSTTSTLSGKSIGRSEQYISPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSAQSRPSSNVGCDQVDFSLNKGLKVKANLDSSISISTDTKKEKSKQNHKSRKHYPRIEAESDSDDYVLDDSDSDDGKCKNCKYKKKYFALRMRMKQVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RPOC_PSEA6
Sequence: MKDLLKFLKQQHKSEEFDNIRIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVAEPGMTTLERSQLLSEEEYLDALEEHGDEFEAKMGAEAVFELLKALDVDADVAAMREELPSINSETRRKKITKRLKLLESFQLSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKLVEREDPEVWDVLDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEARALMMSTNNILSPANGEPIIVPSQDVVMGLYYMTRDRVNGLGEGMMFTSPDEAEKAYRTGNAELHARVKVRITEYDVAEDGSKTEKVTLTDTTVGRAILSLVLPKGLPFELINQAMGKKMISRLLNACYRTLGLKDTVIAADQIMYTGFHYAMIAGASVGIDDMVIPDAKKDIIEGAEAEVREIQEQFQSGLVTAGERYNKVIDIWSNANEKVAKAMMENLSIETVKNRDGEMEDQASFNSVFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVINNEDCGTFEGVKMTPLIEGGDVVEPLRERVLGRTVAEDVLKPGTNEILVERNVLLDEALVDMLESNSVDQIQVRSVITCENDFGVCAKCYGRDLARGHMVGHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKTTGTLKLQNAKFVRNTDDKVVIVSRSTEITIIDDQGREKERYKVPYGAILTTDDNATVTSGEVVANWDPHSHPIVTERQAKISFADIDDSNTEMQQDELTGLTRIVVNDLSKANAKEPKLILESDEHGLQEIRLPSFTTIEATDGMQAKPGDVLARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEVSGTIGWGKETKGKKRLVITPKDADAYEEMIPKWRQLNVFEGENVEKGEVIADGPESPHDILRLRGISAVSNYIVNEVQEVYRLQGVKINDKHIEVVIRQMLRKCMITYAGDSNFLEGEQVEVSNVKIANRELEKQGKIPAQYETQLLGITKASLSTESFISAASFQETTRVLTEAAVQGKEDELRGLKENVIVGRLIPAGTGFAYHQKRTARKLAERQAVEELSVSAADAEQALTEALNAEVMDTPSSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MNMA_LIMF3
Sequence: MTDNSHTRVVVGMSGGVDSSVTALLLKQQGYDVVGVFMKNWDDTDENGVCTATEDYKDVAKVATQIGIPYYSVNFEKEYWDRVFTYFIDEFKKGRTPNPDVICNKEIKFKAFIEYANQLGADYVATGHYADLKRDEAGNMHLMRAKDQTKDQTYFLSQLDHAQLDKVLFPLAGYTKKEVRQLAKDAGLVVADKKDSVGICFIGEDGHFREFLSQYLPAQQGEMQTVDGKVVGTHAGLMYYTIGQRKGLGLGGTKENNDPWFVIGKDITKNVLYVGQGYENEHLYATHMEASDIHWVDDVVSRYGMEFHCTAKFRYRQKDEGVTVKLSDDGQMVTVTSDDPARAITPGQAVVFYDGDECLGSAIIDRAYNQERQLQYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLL_SYNPW
Sequence: MTTTLKRPTDGEGSVQVHQDPSVNIEEETLVIAVYGKGGIGKSTTSSNLSAAFSKLGKRVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPEDFVFSGFNGVQCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVQAIQAKAKNYKVRLGGVVANRSADTDQIDKFNERTGLRTMAHFKDVDAIRRSRLKKCTIFEMDDDDEAVQAVREEYLRLAQNMLDNVEPLEATSLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RUVA_STACT
Sequence: MYAYIKGKLSQLFPTHVVVETNGVGYEIQTPNSYRFQQYYQQEVTIYTSLVVREDAQLLYGFMSEEEKGMFLSLNKVTGIGPKSALAILAASTPNEVKIGIENENETYLTKFPGIGKKTARQIILDLKGKVQITEENPETLLNFEGSESNQTSPILDEALLALEALGYSKRELNKVEKKLQAESYTSVDEAVKAGLKILVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MUTS_FINM2
Sequence: MAYTPMIKQYKEIKEQNKDCILFFRLGDFYEMFFDDALIASKELEIVLTQRDCGENKKCPMCGIPYHVSDVYINKLVSKGYKVAICEQLEDPKLVKGLVKRGIIKIYTPATVIENENSDTGNFNYLMSISKKSNEVAISYIDISTGDVSYTNTTSDDIYKIIENEISKITPKEIIFNDHEFSTNSLETIASKFSIVLTTVNNGTDSIDFINSKITYDNTNSETTNICVANLLKYVFRYQDDLVHINSSRKYYINEFMEIDSNSVINLEIQKNLYTNSKNGSLFGVLNHTKTSMGSRLLHSYLERPLMDKEEILIRQNRVEEIFEDYELLVNLENCLDGIYDLDRLIAKLSYKSANAKDLIALKVSIEKIPYLKNLLNCNKKNVQLIGEKLDDLRDIYDLIDKSIVDDPPVILTEGNLIKPNFSNELDQLRYNRVNGKNELVEYEMSEKDRLGIKNLKIVFNKKLGYFIDVTKSNLNKVGEDYEKRQTLTNSSRFKTKQLEAIESKILDSEDEIFELEYKIFEDIRKIILENLSRIKKSADLIAIIDVSNSLAKCAYLNNYIKPDINTYGLIDVLESRHPIVELSVGQSEFITNDILIGSGKNDIQLITGPNMSGKSTYLRQVALICILNQIGSFVPATKANISIVDKIFTRIGSSDNLFKGESTFMVEMKEMSNIIKYATSNSLLVLDEIGRGTSTYDGLSLAWAIVEYISKDIKAKTLFATHYHELTELEKKLDNLINMKVDIKETNDSIIFLRKITRGSTDKSYGIEVAELAGMPKTLIKRAKSILKEIDKEDTKIDLPIADFAVQNEMEDDKNIHELKDFKDEIKNINVNEITPIQSLQLLNELVIKASKLGD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RPOZ_ACIF5
Sequence: MARVTVEDCLEHVDNRFELTLVAARRARQLASGAAPEVEPGRDKNTVIALREVAAGKVSRAILDEQMPPPLPNFPGAANREATGAEDAAGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.