PharMolix/UniProtQA huggingface dataset:
Protein: IF4A3_CHICK
Sequence: MSGSAGSGGTTGSARKRIMKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase.  Involved in pre-mRNA splicing as component of the spliceosome.  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  Its RNA-dependent ATPase and RNA-helicase activities are induced by CASC3, but abolished in presence of the MAGOH-RBM8A heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation.  The inhibition of ATPase activity by the MAGOH-RBM8A heterodimer increases the RNA-binding affinity of the EJC.  Involved in translational enhancement of spliced mRNAs after formation of the 80S ribosome complex.  Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions.  Shows higher affinity for single-stranded RNA in an ATP-bound core EJC complex than after the ATP is hydrolyzed.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms; the function is different from the established EJC assembly.  Involved in craniofacial development.
What are the official names of this protein?
Eukaryotic initiation factor 4A-III, eIF-4A-III, eIF4A-III, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD box protein 48, Eukaryotic translation initiation factor 4A isoform 3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA.
Protein: GAL1_SALSV
Sequence: MNLKEKTRALFAEIFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRTVRVIAADYDNQVDEFSLEAPIVTHDSQQWSNYVRGVVKHLQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGAKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVASELDPVVAKRVRHVLSENARTVEAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVDIVKATIGDQGGVRMTGGGFGGCVVALIPEDLVPAVQQAVAQQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_AZOSB
Sequence: MSIIDNRKAYHDYFIEEKYEAGLVLEGWEVKAIRAGRANIKEAYIIVRGEEIFILGMHITPLASASTHIRTDPTRTRKLLLHGAEIARLIGKVERAGFTLVPLDLHYAKGRVKAEIGLAKGKKQYDKREDEKKRDWEREKQRLMRVKA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SRY_PONPY
Sequence: MQSYASAMLSVFNSDDYSPAVQQNIPALRRSSSFICTESYNSKYQCETGENSKGSVQDRVKRPMNAFIVWSRDQRRKMALENPKMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAKMLQKSCSSLPADPASVLCSEVLQLDNRLYRDDCTKATHSRLEHQLGHLPPINTASSPQQRDRYSHSTELYDNRVTLATKTYLDAAFYDNLQPSLSYV
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: EF1A_CRYNB
Sequence: MGKDKLHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQELGKSSFKYAWVLDKLKAERERGITIDIALWKFETPRYQVTVIDAPGHRDFIKNMITGTSQADCAILIIATGIGEFEAGISKDGQTREHALLAFTLGVRQLIVACNKMDTCKWSEDRFNEIVKETNGFIKKVGYNPKAVPFVPISGWHGDNMLEETTNMPWYKGWTKETKSGVSKGKTLLEAIDAIEPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKAGMVVKFAPTNVTTEVKSVEMHHEQIPEGLPGDNVGFNVKNVSIKDIRRGNVCGDSKNDPPMEAASFNAQVIVLNHPGQIGAGYTPVLDCHTAHIACKFAELIEKIDRRTGKVMEAAPKFVKSGDAAIVKLVAQKPLCVETYADYPPLGRFAVRDMRQTVAVGVIKSVDKTEKGGKVTKAAEKAAKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_HELPJ
Sequence: MLENRVKTKQIFIGGVAIGGDAPISTQSMTFSKTADIESTKNQIDRFKLAGADLVRVAVSNEKDALALKELKKVSPLPLIADIHFHYKFALIAAQSVDAIRINPGNIGSKDKIKAVVDACKEKNIPIRIGVNAGSLEKQFDQKYGPTPKGMVESALYNAKLLEDLDFTDFKISLKASDVVRTIEAYRMLRPLVIYPFHLGVTEAGNLFSSSIKSAMALGGLLMEGIGDTMRVSITGELENEIKVARAILRHSGRLKEGINWISCPTCGRIEANLVDMASKVEKRLSHIKTPLDISVMGCVVNALGEAKHADMAIAFGNRSGLIIKEGKVIHKLAEKDLFETFVIEVENLAKEREKSLKD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL3_PSEFS
Sequence: MTIGVVGRKCGMTRIFTEEGVSIPVTVIEIEPNRVTQFKTEETDGYRAVQVTVGERRASRVTAAQAGHFAKANVAAGRTVMEFRLEDGDYQAGDLINAEIFAAGQLVDVTGQSKGKGFQGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHMGAERVTVQSLEVVRVDAERNLLLVKGAVPGATGGNLVVRPAAKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TIG_SOLUE
Sequence: MALVEGCKHSLEISIPAAEVETETNRVVLDVQKRAKLPGFRPGKSPASIIRKQFAGDIRQQVLESLIPTHLQKQLEAENLNVVGTPDISDVHFHDNEPLRFKATFEVVPEIELGEYTNIEVPYQDPEVTDEDVTSRIDEIREQKAQYVNIDPRPLADGDFAVVSLESLEGVSGDPVKTDEMQLEIGAKETFEAFNENLRGLSPGDEKDFEVEYPADYGSEKLAGRKVKFHAVVKGLRKKELPELDDEFAQELGDYRTVDELKEAVRKAIFSQRQYEAQQEAKNKIVDKLVDAHEFPVPEVFVERQIRNRVEQSLRAMAEQGVDPSKLKLDWEKVKEAQREKATREVKASLLLGKVSDREAIRATRDEVDAEVEKAARQQRKPVAAVHMEFEKDGTLGRIASHIQTDKTLSFLFERARKTAES
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: BPT_SHEON
Sequence: MNSNANNTPIAIGISQVFPCSYLDGQQEQLLVIQEETLDPILFERLLAIGFRRSGSAIYKPRCPRCSACQPIRVPIQEFVPSKRQKRTLAHNRDLTWRITTEHTETQYALYEKYIRERHFDGPMYPPSKAQYEQFLFCHWLPPTFIEVYDDNRLVAVAVTDTLPNSFSAIYSYFDPDEERRSLGVLLILLQCRLAKLQGKAFLYLGYQIDANRKMSYKRLYRPYQILTHQGWEYSQVC
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DG17_DICDI
Sequence: MSIDIKFTINDILFNQESLQKKNKYTCPICFEFIYKKQIYQCKSGHHACKECWEKSLETKKECMTCKSVVNSYNDLSRCLMVERAFDKKECCCIYSFNEQIVEGGTNCSPPDGASDQNQRKLIKDEENGCKEKIEVDQIDSHLINCQYKFVTCSFKGCEKILRMNSLESHQNECGFKLVTCDFCKRDDIKKKELETHYKTCPMVPIDCSQGCSVKIERKSIIDHIENDCCNTQIPCKYFEQGCKVEMKRSELQNHLERVNHQNYMGILIEKLTNQVGQSKKTHDELLKKIEDLSLLVIKFSDACLKKQVLPKALDICSNGYRNKWIISNYSSVAKSKLNCQALSSPMLSILSHLFQVCVYPKGDENKEYISLYLRVNNIEEPNSLKVEYSFTLVNVLDKSKSITKKEDKKVFISSEGWGWGKFLLSDLINKENGWLSNDDKLIIEIYIKILNEEYEPLES
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
RING finger protein DG17, Probable TNF receptor-associated factor DDB_G0290961.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRR49_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLTHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPNNMSDRGLFNKETSALLEKLAYKASDRNNLDGKQLVLYAAGEKRIGTKKVYAMVQCTKDLIFTKCFECLEGILRKFPQCCDGKRGGRVFGTSCNFRYELYPFLRN
What are the official names of this protein?
Cysteine-rich repeat secretory protein 49.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA2_LISW6
Sequence: MSIKAEEISSIIKQQIENYHSELKVSDVGTVTYIGDGIARAHGLDNAMAGELLEFSNGVMGMAQNLETNDVGIIILGPYTEIREGDEVRRTGKIMEVPVGEALIGRVVNSLGQPVDGLGPIETTGTRPIEAVAPGVMQRQSVNEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTILNQADQDMICIYVAIGQKESTVRNAVETLRHHGALDYTIVVTAAASQPAPLLYLAPYAGVAMAEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSLGGGSITALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQIKAMKTVAGTLRLDLAAYRELESFSQFGSDLDAATRAKLERGKRTVEVLKQDLHKPLKVEKQVLILYALVHKYLDDVPVHDVLRFESEMNTWFDHNRPELLEEIRTTKKLPDEAKLEAALKEFKNTFVPSEEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAV2_OTOGA
Sequence: MGLETEKADVQLFMDDDSYSHHSGVDYGDPEKFVDSGQDRDPHRLNSQLKVGFEDVIAEPVTTHSFDKVWICSHALFEISKYVLYKFLTVFLAIPLAFVAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRSFSSISLRLSQD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27- phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.
Protein: ISPH_NEOSM
Sequence: MQIFVACPRGFCAGVERAIETVEIAIRRYPEKKIFVYHEIVHNSRVIQDFKARGVDFIEDITKVEPKSVLIFSAHGVSEEIEKYVKSLDLVLVDATCPLVSKIHREVQRFEKEGFIILVIGNRNHAEIIGTVGRTKTQAYIVQDPEDIDNLPSITGKLAYVTQSTLALEYTSTMINKIKEKFPNVVGRSDVCYATQNRQEAVKALAKEVDLMLIVGSTNSSNSRNLMQVSSKICQKAFLIDNYNEVEPDWFEGVDRVGISSGASAPEILVQDLVSFLKKRFPSAEVSDFKFKEEKVQFKLPII
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ACPS_LISMF
Sequence: MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEILQVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_SHELP
Sequence: MDKKTSRLRRATRARKKIQELGVNRLVVHRTPRHTYAQVIDANAQVVAAASTAEKAVSEQLKYTGNVEAAKAVGKTIAERAIEKGVTVVAFDRSGFKYHGRVAALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y644_MYCLB
Sequence: MGMRPAARMPKLTRRSRTLIMVALGVIVLLLAGPRLVDAYVEWLWFGELGYRSVFSTVLVTRVVVFLVAGLVVGGIVFAGLAVAYRTRPVFVPSHDNDPVARYRAMALSRLRLIGVGIPAAIGLLAGIIAQSYWVRIQLFLHGDNFGIRDPQFGKDLGFYAFELPFYRLVLSYVFVAVFLAFVVNLLAHYIFGGIRLSGRTGALSRLARLQLVSLVGVLVLLKAVAYWLDRYELLSRTRSSKPFTGAGYTDINAVQPAKLILIAIALICAAAVFSAITLRDFRIPAIGLVLLMLSSLIVGTGWPLIVEQLIAKPDAVRKESEYIRRSITATRHAYGLTEDVVTYRNYIGDAPAIAQQIATDHATTSNIRLLDPTIVSPAFTQFQRGKNFYYFPDQLSIDRYLDKKGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPQFLVNVVGNGTVVSEGPARLDQPRVYFGPVISNTSADYAIVGKNGDDREYDYETNTDTKRYTYAGSGGVPIGSWLSRSVFAAKFAERNFLFSSVIGSNSKILFNRDPAQRVEAVAPWLTTDSSVYPAIVNKRLVWIIDGYTTLDNYPYSERTSLSSATADSTEVAFNRLAPDKRVAYIRNSVKATVDAYDGAVTLYQQDEYDPVLKVWMKVFPGTVRPKGDITPELAEHLRYPEDLFKVQRMLLAKYHVNDPGTFFNTSDFWDVPLDPNPTASSYQPPYYIVAKNILKNDRSASYQLTSAMNRFKQDFLAAYISASSDPETYGKITVLTIPGNVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVAQGGLLYVEPVYASPGVSDAASSYPRLIRVAMMYNDKIGYGPTVGDALTGLFGPGAASAATGIEPTEAVPPKSPAGSSTPPIAVVPSAPDGSVALSAAKAAALQEIQAVIGAAREAQKKGDFVAYGSALQRLDDAITKFNSTK
What are the official names of this protein?
UPF0182 protein MLBr00644.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPTB_ASPFU
Sequence: MKLIPFPYPLNIGTDVVHLPRILRLINRPDYFHRFTRRILHEQEQRDFRTRFSLPPPSSGAEKTGLNPITPDMARWLAGRFAAKEAARKAAPAGASSLGWKDVIVRVGEADKGRPEIVYLDPMGCGETGGGRVGKLSISHDGDYVVATVLAAG
What is the function of this protein?
Acyl-carrier-protein synthase transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of an acyl-carrier-protein (PubMed:21195204).  The 4'-phosphopantetheine (4'-PPT) portion of CoA provides the essential prosthetic group for a number of carrier proteins and multi-domain enzymes, priming them for the acceptance of acyl building blocks in fatty acid synthesis and many aspects of secondary metabolism mediated by polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) (PubMed:21195204).  PptB is specific for the mitochondrial acyl carrier protein acpA (PubMed:21195204).
What are the official names of this protein?
4'-phosphopantetheinyl transferase B, mitochondrial, PPTase B, Acyl-carrier-protein synthase pptB, Phosphopantetheine:protein transferase pptB.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PYRB_CERS1
Sequence: MTFRARHLLGIEHLAPDEIRSVLDLADSYVDLNRRTMKQSDALAGMTQINMFFENSTRTQSSFELAGKRLGADVMNMAVAQSSVKKGETLLDTAMTLNAMHPDLLVVRHPASGAVNLLASKVNCAVLNAGDGRHEHPTQALLDALTIRRAKGRIQRLTVAICGDIAHSRVARSNLILLGKMENRVRLIAPPTLMPPGVGEFGCELYDDMKKGLEGADVVMMLRLQKERMDGAFIPSEREYYHRFGLDAEKLAFAKEDAIVMHPGPMNRGVEIDGTLADDINRSVIQDQVEMGVAVRMACMDLLARNLRAERGRAAVGVMA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y79B_METJA
Sequence: MKGINPFYFYIGMALILASIVSILLITKSILLFILLAFGSLVGITLILIYISRKILKIDKGRLKKEVKRIFGNRVYKILRLMLVLGYAGFIYFSGTFYNSAVLFFIFIVAFTISEFYKTYRIRIYEKGILIEGIAFYSWEEIEKTTNKDKNQTILKIKGIPKKIVINEII
What are the official names of this protein?
Uncharacterized protein MJ0795.1.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1249.1, MJ0210.1 and MJ0785.1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAP3_CRIFA
Sequence: MLRRSPTLLRVSPFSLYMKDLAKNGTLQNDRNPAKTASRLYRKLSEPEKMALQKRAARVSYPALDAYNRFQKEYAHRFLHLSNKKRQREVSKLWAELKKNGTVKVPKAPKAAKSASSKVKTAAKTAKKTTAARK
What is the function of this protein?
Histone H1-like DNA-binding protein involved in the organization and segregation of kinetoplast DNA (kDNA).  The mitochondrial DNA of kinetoplastid protozoa consists of about 5,000 minicircles and 20 to 30 maxicircles.  These circular DNAs are held together by catenation into a highly organized compact disk structure referred to as a kinetoplast DNA (kDNA) network.  Binds preferentially to a specific fragment of minicircle DNA and is able to compact kDNA networks through DNA charge neutralization and condensation.
What are the official names of this protein?
kinetoplast-associated protein 3, Histone H1-like protein p17.
What is the protein family that this protein belongs to?
Belongs to the KAP family.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast.
Protein: SSRP_BACHK
Sequence: MPKGSGKVIAQNKKAFHDYFIEETYEAGLVLQGTEIKSIRAGRVNLKDAFARVHNGEVWVHNMHISTYEQGNRFNHDPLRTRKLLLHKKEIEKLAGASKETGYALVPVRIYLKNGFAKMALGLAKGKKQYDKRHDLKEKEAKREIARAFRDRQKM
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GLGB_BACAN
Sequence: MSVINCEEVKRDEFHTEKYYESYNIFGAHIVTEDEMRGVRFTVWAPHAKAMSVVGDFNEWDYEQHKMLQVTEEGIWSLFIPHIEEREIYKYAIETMAGDVIFKADPYAVYAEVRPNTASVVFDIKGYEWNDKNWSRKKKKKSVYKEAMTVYELHFGSWKKKEDGTLYSYREMAEELIPYVVEHQFTHIEIMPLVEHPYDRSWGYQGTGYYAATSRFGTPHDLMHFVDECHKYGIGVILDWVPGHFCKDAHGLYLFDGTPTYEYKDKDVQENPVWGTVNFDLGKREVRNFLISNALFWMRYFHIDGFRVDAVANMLYWNKEGQEQSNEHAVSFLRELNEAVFAEDEDFLMTAEDSTAWPLVTAPTYEGGLGFNYKWNMGWMNDVLKYMECAPEYRKYIHDKMTFSLLYAYSENFILPLSHDEVVHGKKSLLNKMPGDYWDKFAQLRLLYGYFFTHPGKKLLFMGGEFGQFDEWKDLEDLDWNLHDFEMHRYMHDYFKELIALYKRSKPLWQLDHSREGFQWIDANNNEQSIFSFIRQGDKQEDALVVVCNFTKATYENYKVGVPDFEYYNEVLNSDAEQYGGSGQVNKKRLKTFQEPYHNQTAHVEITIPPFGVSILRPVKTRKGSKKQDGSKTKVRSNVTSRGKR
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.