PharMolix/UniProtQA huggingface dataset:
Protein: EGTA_MYCTU
Sequence: MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADPFRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSALANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDAGPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGASGDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYHLTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDTAARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGIASAVTGMMHGAS
What is the function of this protein?
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC) (PubMed:16262797).  This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine (By similarity).
What are the official names of this protein?
Glutamate--cysteine ligase EgtA, Gamma-glutamylcysteine synthase, GCS, Gamma-ECS.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
Protein: MDH_ROSS1
Sequence: MRPKISIIGAGFVGSTAAHWIASKELGDVVLVDIIEGVPQGKGLDLLQAGPIEGFDVKITGTNDYSATAGSDIIVVTSGAPRKPGMSREDLIRVNADITRDCISKAAPLSPNAIIIMVNNPLDTMTYLAKQVSGFPKNRVVGQAGVLDTARYRTFIAMEAGVSVEDIQAMLMGGHGDEMVPLPRFTTISGIPVTEFISKERLDAIVDRTRKGGGEIVNLLKTGSAYYAPSAATVQMVEAILRDKKRVLPCSCYLEGEYGLNDIYFGVPCVLGAGGVERVLELPLNDEEMALVKKSAEAVSSSIAALKAM
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: UVRC_CAMJR
Sequence: MIKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQKASCKSPCIFYQISRCLAPCDKLISREKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEVKVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIRNDIQWDQNEIYKQLILENFSMDIPLLANVIYVYEEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNSHLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGANVDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLSSGVIQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIT_ECO8A
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATIWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ITM2B_MACFA
Sequence: MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: HPRK_CHLL2
Sequence: MNFDQKGMKKRSITVAYFFENIGRNHDIKLRRLNRVDEQKRRISERELHRPGLALAGFTNLFTYKRVQILGNTETRFLNNHDEAERRKAFENLVRFKVPCIILTSTNKLQPELLEMATEAGVPVYATRHSSTKAMYLITDFLDDQFSLHQQYHGSMVDVCGVGVLLTGKSGLGKSEIALDLIERGHGLVADDVVIIRRKGESLVLNARRNDIIDHFMEIRGLGVVDVKANFGIRAIRDIKDVQVVVELLEWNRETDYERLGLDMKSIKILGVEVPLVQLPIFPGKNIAVIIEVVALNFLLKHYSNYVAAEALTERIRTSIDKGNEQDDES
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: MAX_DROME
Sequence: MSMSDDDRDIDIESDEDGDSDTGLGSSRHTNTANFTQAEKRAHHNALERRRRDHIKESFTNLREAVPTLKGEKASRAQILKKTTECIQTMRRKISENQKDIEEIKRQNNIIAKQIQALESSNGDQFSEFLSDEEVGSEEADDEDLDQDFSRRNKKMKTFHA
What is the function of this protein?
Transcription regulator.  Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'.  The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor.
What are the official names of this protein?
Protein max, dMax, Myc-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the MAX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_KLEP7
Sequence: MSSLSKEAVLVHEALVARGLETPMRAPVQEIDNETRKRLITGHMTEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFSGLDYSRFPKITVIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RIHA_ECOL5
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLCESEEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: TRMD_METCA
Sequence: MRFDIVTLFPEMVRDAARYGVTGRALAAGKVSLEVWNPRDFTRDRHRTVDDRPYGGGPGMVMKVEPLRDAIRAAKGQATPGARVVLMSPQGTRLDQAAVRRFAAAPGLILVAGRYEGVDERLIETEIDEEWSIGDYVLSGGELPALVVFDAVVRLLPGVLGDAESAEQDSHAEGLLDHPHYTRPERVAGRDVPAVLQSGNHAAIGRWRLKQALGKTWLKRPDLLACRVMTPEQLELLDEFKREFELQKNRG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SALCH
Sequence: MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPLMWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKAAVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RS7_RHOPT
Sequence: MSRRHAAEKREVLPDPKFGNIIVTKFMNSVMYAGKKSVAESIVYGAFDLIEAKTKQPPLGVFEQALDNVMPTIEVRSRRVGGATYQVPVEVRSTRRQALGIRWLITAARGRNEKTMTERLSAELLDASNNRGNAVKKREDVHKMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL3_JANSC
Sequence: MLRSGVIAKKVGMTRLFMEDGKQIPVTVLQLDKLQVVAKKTSDSDGYSAVQLGAGTAKAKRTSAPMRGVFAKASVEPKRKLVEFRVDADNLIEVGEEIIADHYFEGQFVDVTGTSIGKGFQGAMKRHNFGGLRASHGVSISHRSHGSTGQCQDPGRVFKGKKMAGHMGAARVTTQNLQIVRTDTDRGLIMIKGAVPGSKGGWVTVKDAVKKPFPENAILPAALASAAAEAAKQAEEAAAAAAAEAEAEAARLAEEQAAAEAESLAQAEAEIAAEGSDAAPEGDADKKDGE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MED21_SCHPO
Sequence: MACRCTQLQDTIDEVATQFYSSIHYLSSHHDFVPLPGQEKVSDSKVNPISAEELQFAQRDLAKDLVTKFMQIDTLINQLPGISTAPKHQLEKIKKLQNSIEEKQLERKSLESENEDLKLQLAKRIETFGRLSCVLFQP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21, Suppressor of RNA polymerase B 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADH1_ARTAN
Sequence: MAQKAPGVITCKAAVVWELGGPVVLEEIRVDPPKASEVRIKMLCASLCHTDVLCTKGFPIPLFPRIPGHEGVGVIESVGKDAKGLKPGDIVMPLYLGECGQCLNCKTGKTNLCHVYPPSFSGLMNDGTSRMSIARTGESIYHFASCSTWTEYAVADCNYVLKINPKISYPHASFLSCGFTTGFGATWRETQVSKGSSVAVFGIGTVGLGVIKGAQLQGASKIIGVDVNQYKAAKGKVFGMTDFINPKDHPDKSVSELVKELTHGLGVDHCFECTGVPSLLNEALEASKIGIGTVVPIGAGGEASVAINSLILFSGRTLKFTAFGGVRTQSDLPVIIDKCLNKEIQLDELLTHEIHLDNIQEAFEILKKPDCVKILIKF
What is the function of this protein?
Involved in the biosynthesis of the antimalarial endoperoxide artemisinin (PubMed:23575629, PubMed:27488942).  Catalyzes the conversion of artemisinic alcohol into artemisinic aldehyde (PubMed:23575629).
What are the official names of this protein?
Alcohol dehydrogenase 1, Artemisinic aldehyde synthase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-IV subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: RL1_XYLF2
Sequence: MVQTKRQKAIDIAVVPGKAYGIDEAIKILKTATKAKFIESVDVAIRLGVDVKKSDQQVRGSTLLPAGTGRDVRVAVFVPSGAKAEDALAAGADAVGMDDLAEKMQAGDLNYDVVIATPDAMRVVGKLGTLLGPRGLMPNPKVGTVSQNPGEAVKNAKSGQVRYRADKAGIIHCVIGKVNFDDEALKLNLQALLVDLIKIKPTASKGTYLQKVSLSSTMGPGVMIDQSTLSLK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: G3P_CERSP
Sequence: MTIRVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGQVETNAHLLRFDSVHGRFPAKVTSGDDWIDVGRGPIKVTAIRNPAELPWAGVDMAMECTGIFTTKEKAAAHLQNGAKRVLVSAPCDGADRTIVYGVNHATLTADDLVVSNASCTTNCLSPVAKVLHDAIGIAKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVSIRVPTPNVSVVDLVFEAARDTTVEEVNAAIEAAACGPLKGVLGFTTEPNVSSDFNHDPHSSVFHMDQTKVMEGRMVRILSWYDNEWGFSNRMADTAVAMGRLL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BRUMB
Sequence: MSRPSTPLLDKAPTPDRLRALPEQDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYDRIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAAKQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANAPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGTGLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGSVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGAAGLSTTVADARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFGSHVLQFLATDGLLDRGFKVRALTLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRDELGHEALPTPFRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TYRA2_ARATH
Sequence: MLLHFSPAKPLISPPNLRRNSPTFLISPPRSLRIRAIDAAQIFDYETQLKSEYRKSSALKIAVLGFGNFGQFLSKTLIRHGHDLITHSRSDYSDAANSIGARFFDNPHDLCEQHPDVVLLCTSILSTESVLRSFPFQRLRRSTLFVDVLSVKEFPKALFIKYLPKEFDILCTHPMFGPESGKHSWSGLPFVYDKVRIGDAASRQERCEKFLRIFENEGCKMVEMSCEKHDYYAAGSQFVTHTMGRVLEKYGVESSPINTKGYETLLDLVENTSSDSFELFYGLFMYNPNALEQLERLDMAFESVKKELFGRLHQQYRKQMFGGEVQSPKKTEQKLLNDGGVVPMNDISSSSSSSSSSS
What is the function of this protein?
Involved in the biosynthesis of tyrosine.  Has a weak prephenate dehydrogenase activity.
What are the official names of this protein?
Arogenate dehydrogenase 2, chloroplastic, TyrAAT2.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: UBP50_HUMAN
Sequence: MTSQPSLPADDFDIYHVLAECTDYYDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA
What is the function of this protein?
Has no peptidase activity.
What are the official names of this protein?
Inactive ubiquitin carboxyl-terminal hydrolase 50, Inactive ubiquitin-specific peptidase 50.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: TX2_HETMC
Sequence: ECRYFWGECNDEMVCCEHLVCKEKWPITYKICVWDRTF
What is the function of this protein?
Inhibitor of voltage-gated potassium channels.  It specifically inhibits Kv2. 1/KCNB1 channels.
What are the official names of this protein?
Kappa-theraphotoxin-Hm2a, Kappa-TRTX-Hm2a, Heteroscodratoxin-2, HmTx2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPP1_TRIVH
Sequence: MTIFRPHLRFLFKPHFLYFQSPAGQSSRPFSTSQILRTALDMPPPPVDTTQRLAKLRELMAQNKVDVYSMQFRYTIKAPLIITVVYSFFFFLLLALKLCLRKTAISQSTLLHVMGVETLIRITAAFISSFTGSAGCAIVSMSKAALSTDGRYFSQAAKQLDSNWTLLKRGVEGVPTWEEWTAEQAENGKVVGVDPSLITAGENLHYTPLTSVVVTNCSYVIADARKLSQTLKTTGGSLVGIDQNLIDAVWGNERPARPANQITVQPVERAGKPFEEKVEDLRKELAAKKRSAMVISTLDEIAWLFNLRGSDIPYNPVFFSYAIVTPSVAELYVDESKLSPEARKHLEGKVVLKPYDSIFQASKVLAESKASASSGSSGKFLLSNKASWSLSLALGGEQNVVEVRSPITDAKAIKNEVELEGFRKCHIRDGAALIEYFAWLENALIKEGAQLDEVDGADKLFEIRKKYDLFVGNSFDTISSTGANGATIHYKPEKSTCAVIDPKAMYLCDSGGQYLDGTTDTTRTLHFGEPTEFQKKAYALVLKGHISIDNAIFPKGTTGYAIDSFARQHLWKEGLDYLHGTGHGVGSFLYAEVPLSASNVLSNEPGYYEDGNFGIRLENLVICKEVQTAHKFGDKPFLGFESITLVPFCQKLLDASLLTEAERKWVNDYHARVWEKTSPFFEKDELTTAWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: Y2221_CITBB
Sequence: MKIWIDADACPRVVKDIVFRASERLKVPVCLVANTDLSRAHTSLITSVRVKAGFDVADDYIAENAEACDLVITADIPLAARVVEKGGVALDPRGELYTEENVGERLSYRNLMAELRTDGLLVGGPAQLGLTDRNRFASALDRLLTKMVREHRSQ
What are the official names of this protein?
UPF0178 protein Gbem_2221.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: T2R40_RAT
Sequence: MAIITTDSDYYTHRYEVIIPFVVSTIDCIVGIIGNGFITVIYGTELVRSKRLPTGEHLMLMLSFSRLLLQIWIMVEITYQLFFPMIYNHNAMYKLFKTISVFLNYCNLWFAAWLNVFYCLKIVNFAHPLFLMMKQKIVVLMPRLMSLSVLVSISLSSFFSKDIFNVYMNTSVPIPFSNSTKMKYFFKTNVLNLAFLYYMGIFIPLFMFIMAAILLITSLKRHTLNMESSTTGSRDSSMEAHLGAIKSTSYSLILYIINALALFISMSNIFGAYSTWNSVCSFILTAYPAGQSVHLILRNPGLRRAWRRFQHHVRLYLKR
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 40, T2R40, Taste receptor type 2 member 18, T2R18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ADH1_GADMC
Sequence: ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDGFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAIDLMKHGKCIRTVLSLE
What are the official names of this protein?
Alcohol dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_RHOP2
Sequence: MLTRKQFELLKFINERLKEAGVPPSFDEMKDALDLRSKSGIHRLITALEERGFIRRLPNRARAIEVIKLPDLGGNSGARRGFTPSVIEGNLGKVRPPSPQHAEDDSDRNVAVPVMGRIAAGTPIEALQTRSHTISVPPDMLGSGEHYALEVRGDSMMDAGILDGDMALIQRNESADTGDIVVALIDEEEATLKRFRRRGASIALEPANSAYEVRILPPNRVRIQGKLIGLYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GOR_HUMAN
Sequence: MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKESLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDASACLQLVMWKVRQRAQIQPRHRSASPAALACP
What are the official names of this protein?
Putative exonuclease GOR, Antigen GOR homolog, RNA exonuclease 1 homolog-like 1.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: METXA_THET2
Sequence: MSEIALEAWGEHEALLLKPPRSPLSIPPPKPRTAVLFPRREGFYTELGGYLPEVRLRFETYGTLSRRRDNAVLVFHALTGSAHLAGTYDEETFRSLSPLEQAFGREGWWDSLVGPGRILDPALYYVVSANHLGSCYGSTGPLSLDPHTGRPYGRDFPPLTIRDLARAQARLLDHLGVEKAIVIGGSLGGMVALEFALMYPERVKKLVVLAAPARHGPWARAFNHLSRQAILQDPEYQKGNPAPKGMALARGIAMMSYRAPEGFEARWGAEPELGETYLDYQGEKFLRRFHAESYLVLSRAMDTHDVGRGRGGVEEALKRLRAIPSLFVGIDTDLLYPAWEVRQAAKAAGARYREIKSPHGHDAFLIETDQVEEILDAFLP
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_MYCTA
Sequence: MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEYGQDLQFTAEVDIRPKISPPDLSALTVSVDPIEIGEDDVDAELQSLRTRFGTLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLDDAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFAQLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPESYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKDVKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQLPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKRVSAGEAEEAEPADEGAARAASDEATT
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.