PharMolix/UniProtQA huggingface dataset:
Protein: FPG_PROM4
Sequence: MPELPEVETVRKGLEKRLKNFYIDNVEVLSERSIASNGGSNVFIFNLKDLVFGRWSRRGKYLIASLCKESDLIEEIPSGTLVVHLRMTGYFEWHQNTKAPCTHTRVRFWNKKGSEIRFIDIRNFGQMWWIPPNKLPSEVINGLKNLGPEPFSKDFNPEYLKYCLKGRKRSIKSSLLDQSILAGVGNIYADESLFEAGITPIKASGDLNGCELKKLCKSLTRILKASIGKGGTTFSDFRDLEGLNGTYGGYAWVYRRNQKPCRKCGTLIEKTKVAGRSTHWCPNCQN
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SOMA_SERQU
Sequence: MDRVVLLLSVLSLGVSSQPITDSQHLFSIAVSRIQNLHLLAQRLFSNFESTLQTEDQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFSSRFLSGGSALRNQISPRLSELKTGIQLLITANQDGAEMFSDVSALQLAPYGNFYQSLGGEELLRRNYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABG_SCHPO
Sequence: MRKVLITGGSSGLGKRIAQIWSQKGHQCHIVGRNEFHLKETLQSLSVAKGQQHTLTIADVQSDMKNLKSIFESVEIDTVVHAAGVLQSSLCVRTSEKEIDSIICTNLVSAIKLSKMAILEWFRNKNSERDRLILNISSRLSTYALPGTSVYAASKAGLESFTKVLAAEVASKGIRVNAISPGYVDTPMLSSQIRAIAEKKVPIGRLASTDEIVDACTFLLDNRYTTGTILPITGGL
What is the function of this protein?
Involved in biosynthesis of fatty acids in mitochondria.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ACP_DESVH
Sequence: MSVEEKVKKIIMDQLGVSAEEVKPEASFVEDLGADSLDLTELIMAMEEEFGVEIDDDDAQKILKVKDAIDYVSNKQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX51A_CORWE
Sequence: MNPLNLSTFIVFTLFAASATTALTCFQCTTSEGSDYCVSSFPKPSQCLPLMNYCTKIITTSNGAISVLRSCNVVSLDNTCMETGTGKICSFSCDTDACNAGSQFHCNRFQLPFLLTLF
What are the official names of this protein?
U-scoloptoxin(05)-Cw1a, U-SLPTX(05)-Cw1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-05 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBB1_CAEBR
Sequence: MSELDQLRQEAEQLKSQIREARKSANDTTLATVASNLEPIGRIQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: MIPO1_HUMAN
Sequence: MENWSKDITHSYLEQETTGINKSTQPDEQLTMNSEKSMHRKSTELVNEITCENTEWPGQRSTNFQIISSYPDDESVYCTTEKYNVMEHRHNDMHYECMTPCQVTSDSDKEKTIAFLLKELDILRTSNKKLQQKLAKEDKEQRKLKFKLELQEKETEAKIAEKTAALVEEVYFAQKERDEAVMSRLQLAIEERDEAIARAKHMEMSLKVLENINPEENDMTLQELLNRINNADTGIAIQKNGAIIVDRIYKTKECKMRITAEEMSALIEERDAALSKCKRLEQELHHVKEQNQTSANNMRHLTAENNQERALKAKLLSMQQARETAVQQYKKLEEEIQTLRVYYSLHKSLSQEENLKDQFNYTLSTYEEALKNRENIVSITQQQNEELATQLQQALTERANMELQLQHAREASQVANEKVQKLERLVDVLRKKVGTGTMRTVI
What are the official names of this protein?
Mirror-image polydactyly gene 1 protein.
Protein: YOAC_BACSU
Sequence: MKKQKGYLVFDIGTGNARVAVVSVTGSVLTVEREDIEYSTETLYPDSRYFSPQVLWKQVMNLAKRALSRSCDIDIIGLTSTSQRQGIVLIDQNGNPFLGLPNIDNRGREWEAGIPDWEEIYSSTGRLPTALFSALKLYGLKQRQPSLWEKTASFTSISDWVTYQLSGILTYEPSQATETLLFDVKQNTWSEEMCDIFGFSPSILPPLVRAGTAIGTIANEYASELGLSINAKVIAGGGDTQLAVKSTGAGLEDIVIVSGTTTPITKITEDHGDTKHKAWLNCHTDQGHWLVETNPGITGLNYQKLKQIFYPNETYEVMEEEISALAKEDHACVAALGSYLSAEKNALTRGGFLFDAPLSAHLKRAHFVRAALEEIAFSIKWNFDILTEVTPFERDYVWVCGGGFQSKALTQYIADLLQKKVYVQEGYHQASVVGAAVICNETFQLTEEMSANVRVIEPKDCQIELALYEEWKQTQRFFSGSESKVLI
What are the official names of this protein?
Putative sugar kinase YoaC.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y1456_HAEIN
Sequence: MFLMWALRLVYVLVSNGYFVKQLFARASIIGVALLLSACATVPMASVEESNTAKQFRSPEKGNSGLYIYRDSFIGKALKKDLYIDDKFIGESAPDVFFYKTIKAGEHKISTESEFSNSDLNIKTESGKNYFIRQYTKFGVFVGGANLEQVSEEEGKKAISKLNMAVSH
What are the official names of this protein?
Uncharacterized protein HI_1456.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PURA_SYNWW
Sequence: MSAVVLVGAQWGDEGKGKITDFLAEKANCVVRYQGGSNAGHTVEVSQEKFMLHLIPSGILYPETLCVIGNGVVVDMGKLIEEIDGLQKRGIDTSNLRISLRSPVVMPYHKRIDELEDRHTRIGTTKRGIGPAYADKINRIGFRMGDILTGGECFRERFKAQIEYKNRIMEEIYQEDGFDYQQMLNEVLGQAEQLKKYLADTSYLVYTAIKEGKKVLFEGAQGTLLDIDHGTYPYVTSSHPIAGGACVGTGIGPTNISKVLGVAKAYTTRVGEGPFPTELNDFQGEILRDKGQEYGTTTGRPRRCGWLDTVILRYAVRINGLTDFAITKLDVLDSFSTIKICVAYRYKGQLLTEFPNNIAILDDCEPEYIELPGWQEDISAASSIEDLPLNARAYVAKIEELTGVKAAIIAVGPKRKQTIVNSPLFT
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_HYDS0
Sequence: MQASEKTLNEIKAKLPYVEVKKDKLLSIVYVQKELLINTLKAIKEDFGFKLFLDHSVVDTLEAQNRFEAFYILYNVDTKERIAVKTRTEHSLPSAEKLWFAAKWAERECYDMFGINYEGHEHLVRAFMWDTYNYHPLRKDFPLQGYETVELPSLNETVFGDNLSNTMNYRRTHTYVPTLKDLEYTEKNRIKKKAQVVLNWGPLHPGTHGTMWFLFDLEGERIVQTDVILGQLHRGVEKLAEHEPYQQFLVYTDRMDYISALCSNQAWTVAVERLLGIEDIVPIKAKYIRTMMSELQRINSHLLWLGTYALDLGALTIFLYAFKEREKIMDIIEGITGARLTISYTRIGGVRMDLPEGALEVIESFIKFFPKELKDWEKILSRNRIWVKRNKNVGVLTKEDIYFYGLTGAVARGSGVFYDIRKLEPYDAYGMVEFDVPLGENGDCYDRYLVRIEEMKQSIRIIEQCVQKLKTMSPNEPFMAESQDPKKLRLTLDGIGLKVPVGEIYSSGENPRGELGFYINSKGGLKPYRVKIRPGSFYNLCVYPHLMENRYVADAVTILASLDPVVGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROA_DESHD
Sequence: MQINNESKGIRINPMGRIQGEIEVPGDKSISHRAALFGGMAQGETHITNFLLGQDCLSTLACLKTLGVEWERRDAEVWIRGRGFENWHEPQDILDVGNSGTTMRLMLGVLAGCPFSATLTGDSSIRSRPMARVTLPLQEMGARILGRQEGKYAPLTIQGGLLQGIQFRSPVASAQVKSAILLAGLRAKGETMVTEPCLSRDHTERMLRGFGVDLKSEGRTAKVRGGAALSGQEVAVPGDISSAAFFLVLGTLIPQGELLIKNVGMNPTRTGILDALWQMGADIQVEEEREECGEPRANLRVRPAQLHGIEIQGEMIPKLIDEVPVLAVAASLAQGETVIRDAAELRVKETDRIQTVVQGLQALGANAQELPDGLRIQGAKSLRGGAAHSHGDHRLAMAWVVAGLLAEEGISLQGIEAAEVSFPNFLELIHEIAES
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_EHRRG
Sequence: MNSDFICLGIITSPHGIKGHVKIKTFTENPQNFTSYGKLTDGITTYEINIIQVVSKNTIIAKINNITSRTNAELLRNKKLFIEKTKLPNLIENEFYHSDLVGLQVILEDNNIFGTIKKIYNFGSCDIIEILLYNSKKSTMLPFSKDIFTHINTKERYVILKLPEIIGSNSGI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF219_IIV6
Sequence: MSLPVNFKIYNPLEALEASHGGGGGITPGSVTGGPGGSIAPGTITSFNLSPGTAASNINSGPDAAVLGSKISKADNTNFGVIEFDPTGDLVQTAAGSGVALLKPGSAANNINSGPPGSINSSQINGGPFLPLSGGTLTGNLVMGPGANITSNPPLNPTDVANKQYVDLSGQKAFAGWTLSSGAFAVSVPAGSTVNAFATTTAPIGNQVWTGADGVTITINGAGIITINNTNTFDTYYVCYFRGNGLLCSNASASPAVYFRFYDETNAANITVEQSLRLISPTIVPAVGGQPFNNYIDFSAFIKVLASSSLNISVKARNPGVDNCLLSTNVSSDVCQVMVIRQG
What are the official names of this protein?
Uncharacterized protein 219L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 219L family.
Protein: HEM3_RUBXD
Sequence: MAGRLVLGTRGSPLALAQAEACAAGLRAAGFAVELRRIRTTSDRRPDDPLSVIDQRDVFTRQLDEALLAGEVDLAVHSMKDVPTEVPEGIVLAAVAGRADPSDALVSEGGWGVDGLPEGARVATSSLRRRAQLLHRRPDLRVVEIRGNVDTRIRKMRAGAAEAVVLARAGLVRLGLEVPHAVIPHDVLLPAVGQGALAVAVRRGDPRLEEIRRALNDPAAEREVAAERALLRALEGGCRVPVGARAVAGGRGVLLRGVVVSPDGAALCGGEERGEEPEEVGRRLAARLLERGAAGILGFVRGVKP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ISPD_HALH5
Sequence: MEYSVVIPAAGQGKRMRAGHNKQFIELGGKPILAHTLAVFEQDDWCTNVVIVANEQEIEEMGELANRYQISKAKKIVAGGRERQESVFAGLKALSQDGLVLIHDGARPFVTEKEIHSLVETAAKTHAAVLAVPVKDTIKRVEGEAVLETMPREELWAVQTPQAFDLALIKQAHQKAENEQMLGTDDASLMEWLGYSVAVVQGSYFNFKLTTPEDLLFAEAILAEKERR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PBL_ECOLI
Sequence: MRSPKVKFLTIFTFCIFITKMSFASNSCSNEAGTMFRIEPNLIKAIALVESNLKKDSIGKNRDKNNNIKSLDYWLMQINQMHIPLLKKRGIIKDERDLLDNPCLNIKIGTEILYNHFSRCGVTWQCLGTYNAGFAMDNQKKRQQYAPKYILYIPGLMN
What are the official names of this protein?
Putative peptidoglycan-binding-like protein.
What is the protein family that this protein belongs to?
Belongs to the IagB/IpgF/P19 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNC_SHIDS
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGM_PROMI
Sequence: MSIERTNPLIPITAISQRNLNEGAQEARKTGNAQTKAMAGDTSVKLSEAQKKLVQPSNQDINVEKVARLKAAIADGTLTMDSSKIAEALFREAAESITK
What is the function of this protein?
Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective.  It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity).
What are the official names of this protein?
Negative regulator of flagellin synthesis, Anti-sigma-28 factor.
What is the protein family that this protein belongs to?
Belongs to the FlgM family.
Protein: Y1349_HAES1
Sequence: MKFSFAALASAMLLTSTAAFAGIVTSSSNIDFLAIDGQKANKDLLKSTKSFNINESQTHQVVVRVSEIVRHGSDRSLYESDPIVVTFQGTNEDVVISAPKLENERDIKNFKDSPSVIVKTNSGRIIATKQEILKQEGFLPGANLIDTLSEYNASGSVASVSSFATAMPAVALGFTKAQKGKVVVQGENIAEQQLQFWFQQADKETQVRFLNWAKNQK
What are the official names of this protein?
UPF0319 protein HS_1349.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: ACP_XYLF2
Sequence: MSDIEARVRKIVAEKLNVDEEKVTNTSTFVDELGADSLDTVELVMALEDEFQCEIGDEAAEKMTSVQHAIDYIKSNAKC
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_PSYA2
Sequence: MPNQRPLYIPFSGPALLETPLLNKGSAFSSEERDSFNLTGLLPHNIETIEEQSLRAYHQLRSFTTDIDKHIYLRNIQDTNETLFHHLIEQHIEEVMPLIYTPTVGQACEKFSQIYRRKRGLFISYPDRHKIDDMLQNATKQKVKVIVVTDGERILGLGDQGIGGMGIPIGKLALYTACGGISPAYCLPILLDVGTNNQQLLDDPMYMGWRNQRISGDEYNEFVDLFIQAVKRRWPEVLLQFEDFAQENATPLLNRYRDQLCCFNDDIQGTAAVSVGTLIAACLNKGQKLSQQKIAFLGAGSAGCGIAEHIIRQMQREGLTEEQARKQVFMVDRYGLLTDSMTELQKFQAPLVQKESAIESWDKSQKLGLAQVVKQAKITVLFGVSGQKGLFTREVIEALCVNTEHPIVLPLSNPTSRVEATPQEVTSWSRGKAIVATGSPFPNTTFEDQSFEISQCNNSYIFPGIGLGVLAAHATGISDNMLMSASQALADISMEYEKAPGAILPPIKFIREISEKIAYAVALQAIEDKLALPVTAENLERRLKANFWLPRYHNYRRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: PSBU_SYNJA
Sequence: MRRLLSALVSILLLLCLCLVPLGIPAVAAELPPVKHLDTPIDVNNTILRNYRQLPGFYPTLARILVKNAPYNSLEDMLQIPELTEQQKALIKANAENFVFGEYQEGANQLENRINQGYYG
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: CAPB_PSESM
Sequence: MSNRQTGTVKWFNDEKGFGFITPQSGDDLFVHFKAIQSDGFKSLKEGQQVSFIATRGQKGMQAEEVQVI
What is the function of this protein?
Affects cell viability at low temperatures.
What are the official names of this protein?
Cold shock protein CapB, Cold acclimation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_YERE8
Sequence: MIALIQRALSANVVVDGEVVGEIGPGLLILLGVEQQDTEQKAQRLCEKVLGYRIFGDENDKMNLNVKQAGGSVLVVSQFTLVADTQKGMRPSFSRGASPAEADRLYQYFVAQCREHGVKTETGLFAADMKVSLVNDGPVTFWLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXPH1_HUMAN
Sequence: MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG
What is the function of this protein?
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
What are the official names of this protein?
Neurexophilin-1.
What is the protein family that this protein belongs to?
Belongs to the neurexophilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAZK_ASPTN
Sequence: MGPASEVYGRKLPFFLGYVLFVLSQIPVALGHDAPTVLVFRFLGGVTSSVCPAITGGWLADFLLPAERGVAVAIFAATTLVGPSIGAITSQVQLQTAMGWRMTAWTTMILGIVSGVAGFIILPETYLPVVEQRHARKLRQETKDWALHSRLDEKPVSIREFLTKYLTLPISMLVSEPILLSMTIYISFTFGLIYLLFVAYPVSFVQERGYGAIDGTLPLLSICAGIIVGAFYASWSTLTTVKQKAASGNALVPEDRLHPMIVGAVSLAIGLLWFAWTSSPAISPWPQILAGIPIGVGVQVILLQSLAYLIDIYTTGAASAISGTMIVRSLVGGTFPLFAPQMYRKFGVSIAVLIIQ
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities.
What are the official names of this protein?
MFS-type transporter tazK, Azaphilone biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRTC3_MOUSE
Sequence: MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHGGSLPNVSQLRNSAPEFQPSLHQADNVRGTRHHGLVERPARNRFHPLHRRSGDKPGRQFDGNAFAASYSSQHLDESWPRQQPPWKEEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENDGHAEVAAFPGPLKEENLLNVPKPLPKHLWESKEIQSLSGRPRSCDVGGGNAFPHNGQNTGLSPFLGTLNTGGSLPDLTNLHYSAPLPASLDTSDHLFGSMSVGNSVGNLPAAMTHLGIRTSSGLQSSRSNPSIQATLSKMALSSSLKCHPQPSVANASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSATSPLNPYPASQMVTSEQSPLSFLPTDAQAQVSPPPPYPTPQELPQPLLQQPHAQEPPTQQPQAAPSLPQSDFQLLTAQGSALTSFFPDVRFDQQPMRPSPAFPQQVPLVQQSHREPQDSFHLRPNPYSSCGSFPGTILTEDTNSNLFKGLSGGLSGMPEVSLDMDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348, PubMed:30611118).  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348).  Acts independently of CREB1 'Ser-133' phosphorylation (By similarity).  Enhances the interaction of CREB1 with TAF4 (By similarity).  Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR (By similarity).  Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity).
What are the official names of this protein?
CREB-regulated transcription coactivator 3, Transducer of regulated cAMP response element-binding protein 3, TORC-3, Transducer of CREB protein 3.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Appears to be mainly nuclear. Translocates to the nucleus following adenylyl cyclase or MAP kinase activation (PubMed:30611118).
Protein: PRMC_BACCR
Sequence: MRVYEALKWASSFLQENGRDENAGEIVLCHVLKVNRTGLLMNMREEITEEQEKSFTEFIHKHVEGIPIQYMIGYEIFYGRSFFVNEEVLIPRPETEELIVGVLERIERHFGDEKLHVADIGTGSGAISITLALENKNLHVYTVDIAQESIEVAKENAKALGAEVTFYHGDLLSPFHKTGQKLDVVVSNPPYIPEEDWRGLSPVVKEHEPKRALVGGEDGLDFYRRFMEELPNVLQKKAIVAFEIGVGQGEDVKRLLQQAFPHAHVEVVFDINGKDRMVFAEME
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: PCNA_NPVOP
Sequence: MEATFATAAAFQSIVGALRGLLTHATFDCDAHGMRLHSLDVERVALADLRLRRAGFARYACERKLSFSVPVRGLVKIVRTADPSAPLTMRVAARDDRVRLAYETARRAVSCTLAQISLDADRLGVPDKEYTCVLAVPSAELTRACADLARLGATTVEMSSGTTGLSFAAHADDGVRVRVLLRGSPQRPLTQAFACCYLNKLARASALSETVDVCMDASMPLRLRFRLGPLGALDLYLAPRVPSVGESAQ
What is the function of this protein?
Sliding clamp subunit.  Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication (By similarity).
What are the official names of this protein?
Probable DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: CBID_SYNY3
Sequence: MSQSISAQSGYTLPVFACASAIAAVETLLTSNCPDSVTLELLEPARTAEIAIEQGALLGHHRALAITRSEPGNNLDLTRHTPVWAEVEFTPGEGKLIIQGGEGIGKQLDREGQAAIYSYAQRLLRHHLQPYISGDQTLMVSLILPLGRTLATRTSNAAFGVVEGLSLLGTSGIAQPLSAPEQLAEFQQHLTSAAQQHQCLVFCLGENGLDLARQWGVPLDQMVKTANWLGSLFVAAAAVGVQEILLLGYHGKLIKLAGGIFHTHHHLADGRLEILTAQAVQAGLPYPLVQELGQAPTTEAGLKLLRHWQTEQNCPWVSKIYQAMADTVDRRSEEYVYKVSQHQLKVGSLLFDGDRQPVAISTQGQAMADKLGMTIPET
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.