PharMolix/UniProtQA huggingface dataset:
Protein: CYB_TAMSE
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLVIQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLILILMMLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPILHMSKQRSMMFRPLSQCVFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPAISLFENTLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MITOK_RAT
Sequence: MTGCSPVFTMQQVVGVSHRLVWRTFRGTDLLMTRTLCSPGPSRPGEKRPEAAALGLYHRLPELGRTLSHTIRNQAASTAKAWWDRYEEFVGLNEVREAQGNVTEAEKVFMVARGLVREAREDLEAQQTKLKEVRDRLDRVSREDNQYLELATLEHRMLQEEKRLRIAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSLQQKDLQNLMVDLRGLVHVGQDQGSGSPTGPSSPRGKDIDGLSAAMKEQLNHSRQVYSCLEGLREQLDSLEKTCSQMAGVVRLAKVPAHPGMVEPLDGALPSSLLEHGSTMLALSEMEQRLEAQANRNAISSTLVTCVTFMATLPLLYMLFKTS
What is the function of this protein?
Mitochondrial potassium channel located in the mitochondrial inner membrane.  Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel).  May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume.
What are the official names of this protein?
Mitochondrial potassium channel, MITOK, Coiled-coil domain-containing protein 51.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AMT41_ORYSJ
Sequence: MAAEAAPEWVEKGDNAWPLAAATLVGLQSVPRLVILYGDCGAVGPRTEKDREAFPPNNVLLTLAGAGLLLWMGWTGFNGGAPYAANVDASVTVVNTHLCTATSLLVWLLLDSFVFGRLSVISAVQGMITGLVCVTPAARLVLHKRSRLLARVDDTLAVLHTHGVAGSLSGVLTGLLLLAEPRFARLFFGDDPRYVGLAYAVRDGRAGSGLRQVGVQLAGIAFVVALNVAVTSAVCLAVRVAVPQLAGGGDAIHGEDAYAVWGDGETYEQYSVHGGGSNHGGFPMTANPVASKADEMIWI
What are the official names of this protein?
Putative ammonium transporter 4 member 1, OsAMT4;1.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KAP3_MOUSE
Sequence: MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.  Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
What are the official names of this protein?
cAMP-dependent protein kinase type II-beta regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Protein: YCF4_PLAOC
Sequence: MNWRSERIWIELITGSRKTSNFCWAFILFLGSLGFLLVGTSSYLGRNLISLFPSQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGKNRRIFLRFFMKDIQSIRIEVKEGLYPRRVLYMEIRGQGAIPLTRTDENLTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRUA_OCEIH
Sequence: MERLKCTVSYDGSDFAGFQVQPDHRTVQGVLEKALYNMHKGKSIRIQASGRTDTGVHAVGQVIHFDSPLEIPERNWKQALNTLLPDDVRIQKVEKKTEEFHARYSVKEKEYHYFVLNEEDPNVFQRGYVYHEPRKLDLERMQEACQYLEGTHDFTSFSSAKSSVKGSKVRTLYHVSCHQTGTNIEFIFRGSGFLYNMVRIMMSVLIDVGKGKRNPEDIIDLLASKNRQQIGKTMAPQGLYLWRVSYEENGNNV
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ZBT37_HUMAN
Sequence: MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSAVLDIRELSPPEESTSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSSGAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVAPGEAVQGSVSTTGPD
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 37.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPYR_ZYGBA
Sequence: MTYTTRQIGAKNTLDYKLFIEKDGKPVSPFHDIPLYADEDKQIFNMVVEIPRWTNAKLEITKEENLNPIIQDTKKGKLRYVRNCFPHHGYIHNYGAFPQTWEDPNVVHPETKAVGDNDPVDVLEIGETIGYTGQVKQVKVLGIMALLDEGETDWKVIAIDVNDPLAPKLHDIEDVEKYFPGQLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIRETHESWKQLIHGQVSDSKGISLTNTTLTDTPTYSAAAASEVPSASPQPDAPVDKSVDKWFFISGSA
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_SHESA
Sequence: MTDQADAAMPIKFTDAAAAKVKGLLEEEQNPALKLRVYVTGGGCSGFQYGFTFDEKVNEGDFTVEKQGVQLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RL16_PSYA2
Sequence: MLQPKRTKFRKMHKGRNTGLAHRGSTVAFGQIGLKSLTRGRMTARQIEAARRTITRKIKRGGKIWIRVFPDKPITNKPLEVRMGKGKGPVEYWVCEIKPGKILYELEGISEELAREALTLAASKLPFKTTIVKRTIM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL25_CUPMC
Sequence: MKVVAFERSVQGTGASRRLRNSGKTPGIIYGGAAEPKMIELDHNALWHALKKEAFHSSILDLEVAGKSEKALLRAFQMHPFKPLVLHVDFQRVSATEKIHVKVPLHFMNQETAPGVKLGHGIVSHILNDLEVSCLPADLPEFIEVDLAAAELNQTIHLSDLKLPKGVTAITHGDENPAIASITLPAGAQSSEAAEGGEETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: J1S_HCMVA
Sequence: PSRTHHAAPHRRCFGCVGARPGGCVPGVSRACVGCVGGVLAGCVRVCRGRVPGVSCRVCRGRVAGVPAGCGGGVCRRCARPRGVRLRRNECVASRPLFPPRSPGPSSLAPGRCFSCVPRDPCCRPPGTSSFPRGITQTQTRVFFSPCAPHVAFIRRRRPPHHTQLVAVHTRNSKFHPPAKNTPPPLEDPPRGPEWMSGVHLDGCAPGRRLCAPVVRACRASSFG
What are the official names of this protein?
Uncharacterized protein J1S.
Protein: AROD_SALTY
Sequence: MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFTFRSAKEGGEQALTTGQYIDLNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRKMQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVADLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.  The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsilon-amino group of a Lys-170 at the active site.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, DHQD, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PGK_STAAU
Sequence: MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_CROAD
Sequence: MGDVEKGKKIFSMKCGTCHTVEEGGKHKTGPNLHGLFGRKTGQAVGYSYTAANKNKGIIWGDDTLMEYLENPKKYIPGTKMVFTGLKSKKERTDLIAYLKEATAK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: RPIA_BORAP
Sequence: MENQKILVAKYAIDRYIKSNMNLGIGTGTTVYHAIKYLSEKLKSGNLKNLKFYTTSSDTKYLLSKEQIPYESNFSKLNKNLDIAIDGADEILLEKKSLIKGMGGAHLMEKVIAYNSETLLIIADETKIVKKLGTKMPIPIEVAPNAVGFIMTRLEEMNLDITLRICNEKKGPIITDNNNYILDVKMHVENPEGTEKYFKLFPGILEIGIFNHKNTKIVYYQNKQIKEA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y689_ARCFU
Sequence: MVWLAELPDEILENLYPGEDVLYSVKKKLYTELKPKYLIVTDRRIIYLDQKILGRYDLIDIPYEKLEFVHFKKGKIGAKFIIRNEEGEEIVLTWMEKDEAEKAIEAIRDAINAIAVEPVSIQKRKGILGFELELSKPKEFITRTYPQAVAKAAPKEDPIERIRKLKELYESGVISREEFEEKKRKLLDQI
What are the official names of this protein?
Uncharacterized protein AF_0689.
Protein: ATPF2_SYNP6
Sequence: MNAWMILAAEAVQEAEGGLFDLDATLPLMAVQILVLVFLLNAVFYKPFGKVLDDRDQFVRGGRQDAKARLAEVKALTAQYEQELAATRKQSQALIAEAQTEAGRIAAQQLAEAQREAQAQREQAQQEIDQQKAVALQALDQQVDALSHQILDKLLARA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DRAM1_XENLA
Sequence: MHCWCLQGAAFLPSILVIWSSAGFLFSYIISVLIGHVPPFVPYISDTGTSPPESGVFGFMISVSAMLGAATMYTRYMILERQNLSIDFLPIYFNKISLAIGLFGCIGMGIVATFQEMAVPAVHDAGALITFICGVMYILLQSYISYKSCPTWNTRATCHIRMTVSLIAFIAVVPMSVFSILSGRKRLDWKPSDEGYPYHLTSAICEWTVAFGFNMYFLTFIRDFQGVSIQISTEIHEDF
What is the function of this protein?
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: ACT_DICVI
Sequence: ISILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MNMG_CERS5
Sequence: MFHVKQFDVIVIGGGHAGCEAAAAAARMGVRAALVTLRPSDLGVMSCNPAIGGLGKGHLVREIDALDGLMGRAADAAGIQFRLLNRKKGPAVQGPRAQADRRLYRAAMQRFLLEQPGLDVVEGEVVDLLLDQGTATGVLLADGTRLDAKAVVLTSGTFLNGTIHIGHDRRPGGRMGDLPSIPLAQRLMDLNLSRGRLKTGTPPRLDGRTIDWTQLEMQPGDADPVMFSFLNHAPVARQISCGITSTNERTHEIVRDNLHQSAMYGGHIEGVGPRYCPSIEDKIVRFADKTGHQVFLEPEGLDDHTVYPNGISTSLPAEVQESYVRTIAGLEEVKILQPGYAIEYDYFDPRELRPTLEVKAMCGLYFAGQINGTTGYEEAAAQGLAAGLNAALAVRGREPLHFSRSDSYIGVMIDDLTSRGVTEPYRMFTSRAEFRLSLRADNADQRLTQTGIDLGCVGPARRDAFLTKMDSLSRGRTMLQQVMLTPTDLARLEIRISQDGTRRSAFDVMAFGEEAASAVERAVPELALLPHDIRQQLARDALYAQFIARQELEAQSLKRDEAVRIPSDFDYGSLSGLSHELTAKLLHARPATIAQAARLEGMTPSALMLILSRLRRASRSAAAG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_DICNV
Sequence: MRIALYPGTFDPITLGHQEIIERGSFLCDRLYIGVAVGHHKKTLFSLSERCELVNGVLADLTLHCPVEVVPYCGLLATLYQKLHANILIRGLRSAGDFEYERQLFYANQHLNAQIETVFLLPAPQYSFISSTLVRELAQLNGALDGLVHDIVKKKLRLNSGGQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_PARMW
Sequence: MSKKYDAGVKEYRDTYWTPDYVPLDTDLLACFKCTGQEGVPKEEVAAAVAAESSTGTWSTVWSELLTDLDFYKGRCYRIEDVPGDKESFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPMAFIKSCYGPPNGIQVERDRMNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDFTKDDENINSQPFQRWQNRFEFVAEAIKLSEQETGERKGHYLNVTANTPEEMYERAEFAKELGMPIIMHDFITGGFTANTGLSKWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDQLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALVAIFGDDSVLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAGKHSPELAIALETWKEIKFEFDTVDKLDVQN
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes alpha-type carboxysomes.
Protein: PVDG_PLAKN
Sequence: MEGKKKRPLFFLLVLLLSHKANNVLFERMNGILLLECENEYVKNENGYKLATGHHYMDNDQIERWLQGTDRSRRVKIEENVKYKYNVEELNTKYEQMKGKRINRILKESTYEAQNVADNNYIDDKANGEYKTDNKTNKGEGARNMVMLDYDISGSGQPDGIIDNVVELLTEDEGNFLKNSSKGDDHPYRMKRKEKMSSGAINQIFLQNNVMDKCNDKRKRGERDWDCPTEKDVCIPDRRYQLCMMEITNLVDTDTHFHSDIIFRKSYSRRRLIYDVGGRGDLLLKKYNNVYSEDLCKDIKWSLQDFGDIIMGTDMEGIGYSLVVQNNLRSIFGTGTSAELDRKKWWNDHKKDIWKAMILSVKEKNRYSAWNCKEDVQIKVEPQIYRWIREWGRDYMSEFREQRRKLNEKCEDKLYYSTMLICTLPPCNNACKSYDEWITGKKKQWDVLSTKFSSVKKAQKIETENIARAYDILKQELNGFNEVTFENEINKRDKLYNYFCVCIVQEARKNTQENVKNVGSGVESKAPSSNPINEAVKSSSGEGKVQEDSAHRSVNEGEGKSSTNEADPGSQPGGPASRSVDEKAGVPALSAGQGHDKVPPAEAAATESAVPHSADKTPITATEENKQRTQVDGVAGGDGKAPGPTVSSDVPSVGGKDSGPSTPASHLAGENGEVHNGTDTEPKEDGEKADPQKNIEVKGKQDTDDRSQGSLGPHTDERASLGETHMEKDTETTGGSTLTPEQNVSVASDNGNVPGSGNKQNEGATALSGAESLESSESVHKTIDNTTHGLENKNGGNEKDFQKHDFMNNDMLNDQTSSDHTSSDQTSSDQTSSDQTSSDQTSSDQTSSDQTSSDQTSSDQTIDTEGHHRDNVRNPEIKSSEDMSKGDFMRNSNSNELYSHNNLNNRKLNRDQYEHRDVKATREKIILMSEVNKCNNRTSLKYCNTIEDRMLSSTCSRERSKNLCCSISDFCLNYFELYSYEFYNCMKKEFEDPSYECFTKGSSTGIVYFATGGAFLIILLLFASWNAASNDYEEEATFDEFEEYCYNIHRTPQMPNDIEHMQQFTPLDYS
What is the function of this protein?
Binds to the human erythrocytes Duffy blood group determinant.
What are the official names of this protein?
Duffy receptor gamma form, Erythrocyte-binding protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CEKI_PAUEC
Sequence: FVVETENQLMSQGGRYYILPVIYGKGGGLG
What is the function of this protein?
Potent inhibitor of serine proteases plasma kallikrein, plasmin and coagulation factor XIIa.  Weak inhibitor of serine proteases trypsin and coagulation factor Xa.  Does not inhibit the serine proteases chymotrypsin, elastase or thrombin.  Inhibits kinin release from HMW-kininogen by kallikrein in vitro.
What are the official names of this protein?
Proteinase inhibitor CeKI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: AKTP2_DROVI
Sequence: MCLETIPTNNKTLALINQGYKVLAEYQMIEQKQLKGIYAIPSYSSGLLWFGVIFIHSGLYAESVFRFSILLPDQFPEESSLPTVIFQKDIFHPHICPVSHSLDLTPLLKEWKKDQHHIWHILKYIQAIFADPEGSVCSTQNGDPIPLTEVNNMEAMRLLANNRVDFAVRAKVSILWSCQHMFDEPPIKDPHYIIFERYCPEKHQAMMERLKSRSWYELSAPKTPKPSVCVARMESARQLIEDEEAQVVNAAGSSLN
What are the official names of this protein?
Protein crossbronx-like.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: GLAA_SHEWM
Sequence: MQRRTFIKSISAMMATSTTLGCVSNSLATEKHVSITDFGLRPNSGDDAIPALQKALAYCKKHPGTSLIFPLGRYDFWSTKADRDFYYISNNDDGIKPVAFPLTEFKNLIIDGQGSRFVFHGGMVPVIVRESSGITLKNFSVDWDVPFHCEGIVEAVNKKESYVDLKIKDGFSYKVENGRFIFVGEGFENPVIKNLLEFDTKRQKQAYMARDNFQREIQPVTTEIRPGVLRLQGKYPTWPKVGNTLLLMQERRDWPAFSVQDTKNTWLENIDIHHSGAMGVIAQLADGIKLDNVNIHPKDGSGRTVSTTVDATHFINCKGHVVLKDCLFQGQIDDGTNVHGMYARVAEIHDSNTITFELVHYQQLGIDIFKPGSKVNFSDSVLNVFHDNVVDKTVRQDAKYWTVSFKEPLDTALKVDDVLDNMTWQPDHVMISGCRFTGNRARGALLTVSGKIIVENNYFSTPMMAIKIGSGGLKWYESGPVESVEIRNNIFDNCNYAKDSSAIDIVPGRKSKATTPYHQNVKIYQNEFRVYNERVLTTSRTQGISFVSNKIVKTSEYPERKSAFAPIHVERSSNFVYQGNDFIGFGHSELLFIDGQLVSGSGKLEGEG
What is the function of this protein?
Alpha-galactosidase that specifically removes branched alpha-1,3-linked galactose residues present in blood group B antigens.  Has no activity toward linear alpha-1,3-linked galactose residues (By similarity).
What are the official names of this protein?
Alpha-1,3-galactosidase A, Exo-alpha-galactosidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 110 family. A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MICU1_DANRE
Sequence: MYRLRALTAATVGMVQLTRRHHTGAFRSYQRRRLMLAALAGVTGISASAGLMWTRAYAEAGSSVKHEEQMREEEPLKDVAEEAESDGALESSSGEDEDEAGSEEKKKKQRIGFRDRKVMEYENRIRAYSTPDKIFRYFATLKIINEHGDAEVYMTPQDFVRSITPNEKQPENLGLDQFMVKRYDGKDFWQKISQDREKFADEDSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDLEEFEQVQSIIRSQTSMGMRHRDRSTTGNTLKTGGCSSALTTYFFGADLKGKLTISSFLEFQRKLQHDVLKLEFERNDPVDGRITEKQFGGMLLAYSGVQSRKLKQMQKNLKRMFKDAQGITFEEVENFFTFLKNVNDVDTALSFYHMAGASIDKATMKQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFIAIMKQRLMRGLEKPKDMGFTRLVRAMWKCAQDTAWDFAMPKQQ
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains.  micu1 and micu2 form a disulfide-linked heterodimer that stimulates and inhibits mcu activity, depending on the concentration of calcium.  Micu1 acts both as an activator or inhibitor of mitochondrial calcium uptake.  Acts as a gatekeeper of mcu at low concentration of calcium, preventing channel opening.  Enhances mcu opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm.
What are the official names of this protein?
Calcium uptake protein 1, mitochondrial, Calcium-binding atopy-related autoantigen 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Note=The topology is subject to debate.
Protein: MBTP2_CRIGR
Sequence: MIPVSLVVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLEKNGLSISPFHIRWQTSVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSSSSSSSSSSSSSSSSIHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKTSSSSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR
What is the function of this protein?
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2.  Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached.  Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription.  Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B).  Involved in intramembrane proteolysis during bone formation.
What are the official names of this protein?
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50A family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm.