PharMolix/UniProtQA huggingface dataset:
Protein: KAL1L_MOUSE
Sequence: MTPALKEATTKGICFSSLPNTMESDKMLCMESPRTVDEKLKGGDTFSQMLGFPTPEPTLNTNFVNLKHFASPQASKHFQTVLLMSSNSTLNKYNENYNQKKVMESNCSKLKNVLCNGSSIQLSKICPSHSENEFIKKELSDTTSQCMKDIQIVLDSNLTKDANVDRLHLQNCKWYQKNALLDKFTDTKIKKGLLQCTQKKIGPSHSDVPTSSSAAEKEQEVNARLLHCVSKQKILLSQARRTQKHLQMLLAKHVVKHYGQQMKFSMKHQLPTMKIFHEPTTVLSNSLLEHTEIKPEVNILASENKFWDDTNNGFSQCTAAEIQRFALSATGLLSHVEEGLDSDATDSSSDDELDEYTIRKNVAVNSSTEWKWLVDRAQVGSRWTWLQAQISELEYKIQQLTDIHRQIRASKGIVILEECQLPKDILKKQIQFSNQAVSLNTSVNSQVPQRSEEPLPEHDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGISRSASENLDELSSSSSWLLNQKHSKKRRKDRTRLKSPSLAIMSTAARTRPLQSFHKRKLYRLSPTFYWTPETLPSKEAFLSSTQTPYTGSPFSWDNWEQSSRSHLLREQVSKLDSSFHPVLSLPSEIPLHLHFETLFKKTDMKGELAENQFVGDCLISPPPVQGTSSLNQWRNGYSPICKPQIRSQPSVQLLQGRKKRHLSETALAGERTRFEEFAFQRSEPGSHCNFTAVSNANVTSRTQNPSSQNTSRRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPRWRKVVLQPLDEHNLNKEEIEDLSDDVFSLRHRKYEEREQARWSLWEQSKWHRRNNRAYSKNVEGQDLVLKEHSSELGSAQQGTAESPFELPAESHSLCAQDSLSLNDGQEDKSLRWERRAFPLKDEDTAALLCQDERKDQTGGTSTAFHDEVFCSTTPESGHPPKMQLDGMEEYKSFGIGVTNVKRNR
What are the official names of this protein?
KAT8 regulatory NSL complex subunit 1-like protein.
Protein: LSPA_DEHM1
Sequence: MTRGLVFFVSAACGVLADQLSKFIIAANLTPGTAIPESGFFQIVHVHNTGAAFSIFRGHTEWLIAASCLGVILALTAFFLRKKLPFLDTRPGVAALGIILAGTIGNLIDRVRLGYVTDFIQVGNFPTFNMADSCLTLGIIWLVLLYLTSSHSGGDASENA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1718_HAEIN
Sequence: MEINREESDLTKYVKITNDTDLTASGTAQNNDAKIENSRLSIAIGHNALVKDSDTKYTHPKDKTPDNPAASIAVGANANVTESPYSIALGKNAKVLNSEYSLAAGTNAKVEKSEKAIVQGVEANATNSNISIVTDFAAKAENSKDVIVLGSKTESIRSNSTVALGNRTSVTDSDSAFVGGDHASATTSAGALVLGNGAKAKTVSLTADNGVLKAGDKTIFTEDNFKMLLKQLYTFEDGLKTKEKNGKTVVSLDKETIKQMA
What are the official names of this protein?
Uncharacterized protein HI_1718.
Protein: THII_YERPN
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKHLEDDTLAIVRHWDHIELRTKDDNLGPEICDALTRIPGIHHILEVEDRSYSDMHNIFEQTLEAYRETLVGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVNLTRPQVTVNLEVDQDKLILVKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFIAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLARQIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVSEAKNVDIREIAQQSREQVVEVETVAELADTDVLLDIRAPDEQEEKPLKLDQVEVRSLPFYKLSSQFADLDQSKTYLLYCDRGVMSRLQALYLREQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_SALSV
Sequence: MTESTFSQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKAESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFF_METMP
Sequence: MITIACAEGGSTIYSLKKAIEDLGEKCNILLLSSDNLLVDTDFNIKTDLIHSRCGIGDYLDRLTLFSWQVLKNLESEGHYFINPLETIYNSSDKFKTTKILSKNGLKTPKTALIRDYADAKHFLDTKNMNYPVILKNSFSKCGMKVQKANSDDELKKLSKNSIWESKLIQEYVDFKNGDTYKDMRILVIDGEVVGGYRRVSNNFITNLYVGGQIEPLNVSSELEEIALKCSECMNGYIMGIDILPKDGEYYVVEVNTAPGTKGFRSLGIDVDKRIAECLIKYKKS
What is the function of this protein?
Catalyzes the ATP-dependent addition of one alpha-linked L-glutamate molecule to coenzyme gamma-F420-2, producing coenzyme alpha-F420-3.  Thus, caps the gamma-polyglutamate tail of coenzyme F420 with a terminal alpha-linked glutamate (By similarity).
What are the official names of this protein?
Coenzyme gamma-F420-2:alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family. CofF subfamily.
Protein: PYG3_ANASL
Sequence: MALPLLEYKPT
What is the function of this protein?
Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome rod-core linker polypeptide CpcG3.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHF6_HUMAN
Sequence: MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQQLNGN
What is the function of this protein?
Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.
What are the official names of this protein?
PHD finger protein 6, PHD-like zinc finger protein.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome, centromere, kinetochore. Note=Nuclear, it particularly localizes to the nucleolus.
Protein: SOMA_LABRO
Sequence: MARALVLLSVVLVSLLVNQGRASDNQRLFNNVVVRVQHLHQLAAKMINDFDDNLLPEDRRLLSKTIPMSFCISDYIEAPTGKDEAQRSSMLKLLRISFRLIESWELASQILSRTVSNSLTANQINEKLADLKMGISVLIKGCLDGQPNMDDNDSLPLPFEDFYLTTEDNDLTKNFRLLACFKKDMHKVETYLRVANCRRSLDSNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: URE3_RHILV
Sequence: MNLTPREKDKLLISMAAMVARRRLERGVKLNYPEAIALISDFVVEGARDGRPVAELMEAGAHVIGRSQVMEGVAEMIHDVQVEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATE_METM7
Sequence: MDYDYEKLGLKVGLEIHQQLNTKRKLFCNCPTKIRDDEPHGEIERVLRPSQSEMGHVDKAALLESKKEKKFIYQYYNDTTCLVELDDEPPHDVAPEAVDTALEVSTLMNMKMADEIQVMRKMVIDGSNTSGFQRTMFVSQEGFIETDYGNIGVTSICLEEDACKKIEDGKDYTKYCVDRLGIPLLEITTEPDITSPKMGKEAARRIGTILRATGKVKRGLGTIRQDVNISIKGGARIEVKGVQNLDLIEKIIENEVTRQISLNEIKEELLKRNAEVIDEIKDITELLKDTESKVLKSALKNKGVIKAILLNGFSGMIGREVQPGRRLGTEFSDRGKVLGGVGGLFHTDELPKYGITEEEVIKLKEFMSCGENDAVILVADKKNKVERALNAVIERAKESMIGIPEETRKALDDGNTSYLRPLPGAARMYPETDVPTITITEEKLEMVRNNLPEMPEEKLVRFVNEYELNEDLAKQMVMSYHVDLFESLAKKYSKIKPTLIATTLEATLKEIKREGLETEVLTEEHLDEVFKGLSEDKMSKEAVPDVIKGFIENPAKNLDEVLEIKGMSSMSVEEVESIIEDIINQNISTVNEKGMGAMGLLMGRCMAQLRGNADGKLINTTLQKKLKEKVQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: RF1_CLOBK
Sequence: MLERLNFIENKYEELSNKISDPSVMANQKEWQKLCKEHADLEIIVNTYREYKKAQEDLESDKEMLKEESDKELREMAQEEIKELTLKLEDLERELTILLLPKDPNDDKDVFIEIRAGAGGEEAALFASNLLRMYTRYAERKNWKVETMSLNATDIGGFKEVTVAIKGKGAYSRLKYESGVHRVQRVPDTESSGRIHTSTATVAVLPEVDDVDININANDLRIDVYRASGHGGQCVNTTDSAVRITHLPTGLVVTCQDEKSQLKNKEKAMKVLKARLFEAAEAERAASIAEDRKSQVGTGDRSERIRTYNYPQGRITDHRIGLTLYKLETFLDGDIDEVIEALVTEDQAEKMKDLGRVN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_SALNS
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWAAFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: RL10_LACLM
Sequence: MSDYKVNEATIAKKAELVDVYAQKMTEAASIVVADSRGLSVDEDTQLRKQLREAGVEFKVVKNSILRRAAEKAGLEGLSEAFSGPSAVAFSNEDVVAPAKVLADFAKDAENLEIKAGVIEGKVSSKEEIQAIASLPSRDGLLSMLLSVLQAPIRNVALAVKAVAEKEESAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: OTSB_MYCBP
Sequence: MRKLGPVTIDPRRHDAVLFDTTLDATQELVRQLQEVGVGTGVFGSGLDVPIVAAGRLAVRPGRCVVVSAHSAGVTAARESGFALIIGVDRTGCRDALRRDGADTVVTDLSEVSVRTGDRRMSQLPDALQALGLADGLVARQPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPGIWYAGSHGFELTAPDGTHHQNDAAAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRHALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVGPHGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRLARQLREAPLRAT
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
What are the official names of this protein?
Trehalose-phosphate phosphatase, TPP, Trehalose-6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: RL4_LACGA
Sequence: MANLEIIDQKGKSAGNVDLNEEIFGIEPNESVVFDAIIRQRAGKRQGTSAVKNRSAVRGGGKKPWRQKGTGRARQGSIRAPQWRGGGTVFGPTPRSYKMDMPRKARRLAMKSVLSQKVADKDLIILDQLTLEAPKTKELKAILDNANVSGKVLVVSDDKNVQLSGKNLPKVKVVPVNGLNVVDAVDYQKLVLTQDAIKRIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: HPR_BLAHS
Sequence: MKIVVLDGYCLNPGDLDWKGLEALGECIVYDRTSLTDMEEVISRIGDADIVYTNKTPMPREVFEKCPNIRFVGVLATGYNVVDVNTAKEKGIPVANIPTYGTASVGQFAIALLLEICHHVGHHNQVVHEGKWESNPDWCFWDYPLIELDGKNMGIIGYGRIGQATGKIAQALGMKVLAYDAYKNPALENENCRYVELDELLSQSDVIALHCPLFPETEGIVNKENIAKMKDGVIILNNSRGPLIVEQDLVDALNSGKVAAAGLDVVSTEPIKGDNPLLGAKNCIITPHISWAPKESRKRLMDIAVNNLEEFLKGSPVNVVNK
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the reduction of 3-hydroxypyruvate to glycerate.
What are the official names of this protein?
Hydroxypyruvate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: RF1_THEMA
Sequence: MKEKKKEIEKLLARPDLTPEQMKNYGMEYAKIEEIENITNRIKETQEFIELLREEGENELEIEKYEKELDQLYQELLFLLSPEASDKAIVEIRPGTGGEEAALFARDLFRMYTRYAERKGWNLEVAEIHETDLGGIREVVFFVKGKNAYGILKYESGVHRVQRVPVTESGGRIHTSTATVAVLPEIEEKDIEIRPEDLKIETFRASGHGGQYVNKTESAVRITHLPTGIVVSCQNERSQYQNKQTALRILRARLYQLQKEQKEREISQKRKSQIGTGERSEKIRTYNFPQNRVTDHRINYTSYRLQEILDGDLDEIISKLIEHDIENNLEEVLGIGASVEEK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_HALS3
Sequence: MSSESPESVDDSTKVQATAEWDPLQAVRMHLPGAETFVGIMDPEPNLFLNDFSLVDAQQEHLSLSQDLEAALPASNPIHYLHDDLANGNGMNALLSSRVNFDLSELGEDEQVNRRDKMWARLHELSPHTQIQAVLGNAEVIRHHSHSDEEVPGSNPDRWDTTSVQLEQPLTNMYFQRDQQFVTQNGVVLCSMKEDTRKPEVDIARASWEALDGDEFDVDIVADMSQVREHDVTEHVPERDDIQETEVLVEGGDFYPAGEFSLLGVSAKIPEGEAYPKHDIAEDDTEYVHRTTYAAGHRLLMDDAFGSEEVGLVRAPFEAAQAHKDDDNGEVEMDIMHLDTWFNFVDDDLVVAHKELVENTTLDVYARTHGGEKPYTLERPDVNFGEYLREKGFEIVDVYDYVDPSHPDTDMALKAITNFLTVGPRKILPVRFSDDDDGVMKQFIDGIQEDYDVTVIPDGEGRKIINLRAGYGAIHCMTTPLRRTPE
What is the function of this protein?
Involved in the arginine deiminase pathway of fermentative arginine utilization.
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_STRMK
Sequence: MSEHPLPASVAATLEQGLASMGLDAALAPPLLRYLALLHRWNGTYNLTAIRDPQEMVTRHLLDSLAMQPFVADGSLADLGTGPGLPGIPLAIACPGLQVTLVESNGKKARFMREAVRQLGLGNARVAESRAEALDEAGRYDQLTARAMDTLAGIVRVGGHLLRPGGVLLAMKGVYPHEEIAELPAGWQVREVTPLSVPGLAGERHLVTVTGP
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_CORJK
Sequence: MGHDSDVRADIAHARRLVVKIGSSSLTDDDGRVDPNQIDMIADALEARMARDTDLIVVSSGAVACGMGPLELAQRPTDLATKQAAASVGQVLLAQEWARSFARYGRTIGQVLLTASDAAERDRARNAQRTIDRLRQLKAVPIVNENDTVATSEMRFGDNDRLAALVSHLAFADACVLLSDVDGLYDRNPAEPGAQFIAEVKSSKDLKGVAAGDGGRLGTGGMAAKVSAARLASRAGVPVLLTSTENIGAALDTAEVGTCFWPDQDRLSAWKFWVLYAADSHGQLHLDAGAVHAVTENHKSLLSVGITKVEGDFSQRDVVDLVGPDGNIVGRGEVAYDSAMLHDLIGQSTSDLPEFARRPVVHADYMSHYSNRAQLKG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_BACCN
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPRRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPRGGKVTGLSKLARTVDTIARRPQLQERITSTVADSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKSK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL22_HYDS0
Sequence: MSIEVVSKAVHKNARISPLKASQVLRLLRGKPVEYAMYQLSFMNKKAAVIIKNVLKSAVANAEQKGIDPTKLVILEAKADKGIMFRKWMPRAHGRATMMRKNTSHITIALGELQEATEEAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: NSA1_VANPO
Sequence: MRVLVSCTDGGSLKEVIFNSGTDTSVQTALQPLHVETHLEQGLNNYINKISQLSNGEFLIARSNGVVELVKATLLPKEYTEEPPEGKQFPSFDVNKFEVVDTLAGLLDNKRLEPLYQKSKKRTKLIDEFVTVTLLNEKLNIYILASKSGLIHIIKHNSKKSKLEKINSFEVKAPLDFAQLYDLEGKMDKYILGYGGEENLVKLIEINKNFTDLKQIWEAKNVKNDRLDMKVPIWPVSLKFLEPYKGEKLEKDKINYQFTTVSRYSHLGKYRTQHGRKPLEYKDLLPNREPLTQLEVISEKVTPIGNAQTSEFSDITFITTDTKKDVLKFNHDGRLLLKYGKGDILGSPTFITISKGKYLLQGGLDRYLRVFDINTNERIAKIYVGAKINYITLLDDDEIELPEVAKEKEKMKEKSKKRELEFEEDNDDQLWNDLDSIKHHKKSKI
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein NSA1.
What is the protein family that this protein belongs to?
Belongs to the NSA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TOP6B_THEGJ
Sequence: MAEASQLFKEFKIQSVSEFFRRNAAMLGYTGKVRSLTTLVHEAVTNSLDACEEAGIPPYIRVEIEELGREHYKVVVEDNGPGIPEKYITHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITSGKATRVITSTGDEIIEAWVKIDVDKNEGKIVKKEKHPNPDGWHGTRIELEVKNVKYMRSKQGVYWYLKLTAIANPHAHIELIEPDGKLIVFPRSSEEVPEPPVEMKPHPKGVLTDDVYRMAKKTKRQSVRRFLIGEFSRISDKKVDELIEYVAALRLIKKVGDKKVQEQLYERLMKGEVKAVLRSFRGYTKVVKQVAKMMEKPPEKLTWHEAEEIVEAFKYMKFLAPPTHGLRPIGEENIEKGLKGILKPEFVTAVTRPPKVYSGGIPFQVEVGLAYGGEIPSGFELLRYANRVPLLFDAGSCVTTQAARSIDWKRYKVDDLDRTPLVLMINVVSVHVPYTGTGKQSIASVDEIYNEIRLAIMDAARRLQTYLSGKHRRLYQVKRKKTFEKYVPEIARALSVLTGESEEKIREYFLNFIESHFASKEAVEVSENA
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: SCF_CAPHI
Sequence: MKKTQTWIITCIYLQLLLFNPLVHSQGICRNRVTDDVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVEQLSVSLTDLLDKFSNISEGLSNYSIIDKLVKIVDDLVECMEEHSFENVKKSSKSPEPRQFTPEKFFGIFNKSIDAFKDLEIVASTMSECVISSTSSPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKASNSIEDSSLQWAAVALPAFFSLVIGFAFGALYWKKKQPNLTRTVENRQINEEDNEISMLQEKEREFQEV
What is the function of this protein?
Stimulates the proliferation of mast cells.  Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture.  Mediates also cell-cell adhesion.  Acts synergistically with other cytokines, probably interleukins (By similarity).
What are the official names of this protein?
Kit ligand, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand.
What is the protein family that this protein belongs to?
Belongs to the SCF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium. Cell projection, filopodium. SUBCELLULAR LOCATION: [Processed kit ligand]: Secreted. SUBCELLULAR LOCATION: [Soluble KIT ligand]: Secreted.
Protein: SIGM3_REOVD
Sequence: MEVCLPNGHQVVDLINNAFEGRVSIYSAQEGWDKTISAQPDMMVCGGAVVCMHCLGVVGSLQRKLKHLPHHRCNQQIRHQDYVDVQFADRVTAHWKRGMLSFVAQMHEMMNDVSPDDLDRVRTEGGSLVELNWLQVDPNSMFRSIHSSWTDPLQVVDDLDTKLDQYWTALNLMIDSSDLIPNFMMRDPSHAFNGVKLGGDARQTQFSRTFDSRSSLEWGVMVYDYSELEHDPSKGRAYRKELVTPARDFGHFGLSHYSRATTPILGKMPAVFSGMLTGNCKMYPFIKGTAKLKTVRKLVEAVNHAWGVEKIRYALGPGGMTGWYNRTMQQAPIVLTPAALTMFPDTIKFGDLNYPVMIGDPMILG
What is the function of this protein?
The viral outer shell polypeptides, of which sigma-3 is one, impose structural constraints that prevent elongation of nascent transcripts by the RNA-dependent RNA polymerase lambda-3.
What are the official names of this protein?
Outer capsid protein sigma-3, Sigma3.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus sigma-3 protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in the outer capsid. Each subunit is positioned with the small lobe anchoring it to the protein mu1 on the surface of the virion, and the large lobe, the site of initial cleavages during entry-related proteolytic disassembly, protruding outwards.
Protein: NDHH_SOLBU
Sequence: MTAPTTRKDLMIVNMGPQHPSMHGVLRLIVTLDGEDVVDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITINGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELIYDLFEAATGMRMMHNFFRIGGVAADLPYGWIDKCLDFCDYFLTGVAEYQKLITRNPIFLERVEGVGIIGRDEALNWGLSGPMLRASGIEWDLRKVDHYESYDEFDWQVQWQREGDSLARYLVRIGEMTESIKIIQQALEGIPGGPYENLEMRRFDRLKDPEWNDFEYRFISKKPSPTFELSKQELYVRVEAPKGELGIFMIGDQSVFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MPC2_SCHPO
Sequence: MFRAGFKRFWNHPAGPKTVHFWAPAMKWTLVLSGIGDYARSPEYLSIRQYAALCATGAIWTRWSLIVRPKNYFNATVNFFLAIVGAVQVSRILVYQRQQKRITAQSEQRTELARSLAA
What is the function of this protein?
Mediates the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Probable mitochondrial pyruvate carrier 2, MPC2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACPS_CERS5
Sequence: MILGIGTDLANIERVEKTLARFGDRFRNRVFTPLEQARAERRADVAGTYAKRWAAKEACSKALGTGLRMGIAWKDMSVANLVTGQPVMELTGWAAERLAAMTPPGHEAIVHVSLTDDHPWAQAFVVIEARPLAAPPA
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.