PharMolix/UniProtQA huggingface dataset:
Protein: DHE2_NEUCR
Sequence: MDSPSAPVPAHKLVDRLKDQTPRHPSPQPTHVSYPKVNGNGHRVLRSATVGYVAPVFQGKAEQMKQVKNIIVQGGWIPETLVDGQIAWFYNELGIDDVYFQLENPQAVANHITSLYAAKVAAFSREDKREEIRLDMEASDHAIYIDTSEPGMTSFDGPRYEHRLESKYLDGDDTSKRFRVETFRSPGVLGQKENSKAALRCYFVYQCLFVDSNADPKETRLEVISDRMFLAKATKNTKQIYQDIIQVAVSRHGPVIEVFDIEGSEEMRLVVAFRSRTAKGIFSALSDLYHYYGVTSSRKYVEQFSNGITVMSIYLRPAANIDGKHPPLEQSIHQITKEISLLYCLPQNKFHNMFASGELSLQETIYAHCVWVFVQHFLNRLGTEYTSLIAALDPKNNSHVEILSKMKKRLRTETFTPDYILEIISSHPQLVRALYASFASVHLRVGSDYDRHLIAPTPVMEVLSDARLKEKITKDVSNEHEEMVMTAFRVFNNAVLKTNFFTPTKVALSFRLNPSFLPEVEYPKPLYGMFLVITSESRGFHLRFKDIARGGIRIVKSRSKEAYQINARNLFDENYGLASTQQRKNKDIPEGGSKGVILLDPKQQDRHREAFEKYIDSILDLLLKAETPGIKNPIVDLYGKEEILFMGPDENTADLVDWATEHARARGAPWWKSFFTGKSPRLGGIPHDSYGMTTLSVREYVKGIYRKLELDPSKIRKMQTGGPDGDLGSNEILLSNETYTAIVDGSGVLCDPNGIDKDELRRLAKARAMISNFDIAKLSKDGYRVLCDDTNVTLPNGEVVHNGTAFRNTYHLRDNGITDMFVPCGGRPESIDLSSVNKLIKDGKSTIPYIVEGANLFITQDAKLRLEEAGCIVYKDASANKGGVTSSSLEVLASLSFDDKGFVTHMCHDSRGNAPEFYQAYVKEVQNKIQDNARLEFEAIWREHEQTGLPRSVLSDKLSLAITSLDEDLQRSELWDNEKIRRSVLADALPNLLINKIGLDTIIERVPDSYLRAIFGSYLASRFVYEFGSSPSQFAFYDFMSKRMGNINKE
What are the official names of this protein?
NAD-specific glutamate dehydrogenase, NAD-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: RECF_RHOJR
Sequence: MFVRALSLRDFRSWDALGLTLRPGCTVFVGPNGHGKTNVLEALGYLSTLSSHRVSSDAPLIRTGTGQAFAGATVVNAGRELTVDLELNEGKSNRARINQSPTRRPREILGILQTVLFAPEDLSLVRGDPGDRRRYLDELLTSRIPRMAAVRADYDRVLRQRSALLKTAGGALRRVSRGSGRPSEDGASALATLEVWDGHLAAHGAQLLAGRLHLVHDLAPHLAESYQSLAPESRPASIRYRSSLGSSLPPEFTEPARVPEAGDIAFLEERFLQELSVMRSKEIERGVCLVGPHRDDLELHLGDTPAKGFASHGESWSFALSLRLAGFALLRSDGSDPVLMLDDVFAELDRRRRRALAKVALDAEQVLITAAVPEDVPEELDAVRFGVEARDTDRGRISHIVEEPEDRSDG
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPE_MYCBO
Sequence: MAGSTGGPLIAPSILAADFARLADEAAAVNGADWLHVDVMDGHFVPNLTIGLPVVESLLAVTDIPMDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVARDIRAAGAKAGISVKPGTPLEPYLDILPHFDTLLVMSVEPGFGGQRFIPEVLSKVRAVRKMVDAGELTILVEIDGGINDDTIEQAAEAGVDCFVAGSAVYGADDPAAAVAALRRQAGAASLHLSL
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: CINAL_GLOC7
Sequence: MSAEIICVGTELLLGDILNSNSQFLGTELAKLGIPHYYQTVVGDNLERLKQVIKIAISRASILIFTGGLGPTPDDLTTQAIAEFFQTPLEENPEILADITEKFAQIGRKMATNNRKQALIPVGADVLPNPSGTAPGIIWQPQEGVTILTFPGVPSEMKQMWQQTAIPFLKSQGWGKELIYSRMMRFRGIGESALAEKVAHLLELANPTVAPYAGLGEARLRITAKAKSLTDAMALIEPVSQEILTLTGDDYYGADQDTLPSVVGQQLRQVAQTVSVAESCTGGGLGEMLTQIPGSSEYFLGGIIAYDNRVKNALLGVNQQDLDQFGAVSEPVAKQMALGVKEKIGSDWGISITGIAGPGGGTDTKPVGLVYIGIADPNGQVEGFEYRLGTRRDRLAIRYLSACNALDQLRRKLLIKI
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: NHP6_CRYNB
Sequence: MPKVSTKDSKKSTASDAKKRTKKDPNKPKRALSAYMFFVQDYRERIKTENPEATFGDVGKLLGIKWREMNENEKKPYEAKAKADKERADRENADYKAEGKASKKAAKADEESDDDE
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein 6.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: IDTM_CLAPA
Sequence: MADDFKVVIVGGSVAGLSLAHCLERLGVSYVVLEKGSQIAPQLGASIGILPNGGRILDQLGIFRDVEDEIEPLNFAVIRYADGFSFRSQYPKALHSSYGYPVSFLERQKFIQILYDKLRGKNHVHTRKRVVSIVDGPGKALIRTDDGDEYDADMVVGADGVHSVVRSEIWRHAKEAAGTAVTEEEPNADIKYDYACVYGISVNVPHADTGVQLSSLSDGVSIHLFAGKGSKFFWFIMVRTSRDEFLELKKDSAHMARRTCEGLGSKRLSDAVYFRDVWSRCTVYQMTPLEEGVFRQWNRGRLVCIGDAIRKMAPNIGQGANMAIEDAAQLSNLIREMLASPRKASATTVEKMLRDFAAMQKARTKSMCGQSEFLVRMHANEGFGRRLLGRYLIPSLQDAPAGLAGLSIRGAVKLECAGVPSRTLGKAWEGSWGSSLRNLMYLRPRLGILSLVYVVAGLAMMYMSIYLVVPARLAAQAFDVSRDGTEGKGGG
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals (PubMed:23468653, PubMed:29457197, PubMed:32077051).  The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyltransferase idtC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation of the two terminal alkenes of the geranylgeranyl moiety by the FAD-dependent monooxygenase idtM, and cyclization by the terpene cyclase idtB then leads to the production of paspaline (Probable).  The cytochrome P450 monooxygenase idtP then catalyzes oxidative elimination of the pendant methyl group at C-12 of paspaline and generates the C-10 ketone to yield 13-desoxypaxilline (PubMed:32077051).  The cytochrome P450 monooxygenase idtQ may catalyze the C-13 oxidation of 13-desoxypaxilline to afford paxilline (Probable).  Considering that both paspalicine and paxilline were detected in C. paspali, idtQ also catalyzes the formation of paspalinine from 13-desoxypaxilline via paspalicine as an intermediate (Probable).  Finally, the alpha-prenyltransferase idtF prenylates paspalinine at the C-20 or the C-21 positions to yield paspalitrems A and C, respectively (PubMed:32077051).  The hydroxylation of paspalitrem A at C-32 by a still unknown oxidase affords paspalitrem B (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase idtM, Indole-diterpene biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: STAT_ANOGA
Sequence: METRLHQLPPCILEQFHFLNDLKYPVLIRQHLGNWIKDSLHNAPTYTNNMQSMYELDAAKFFTALVNEVDQVSANLPNKRKCLLCRSAIMLRDQNFQNLTQLYLTLLHQIQPNCEKGCKTEYTIAQTSSDGQQTDVLYGLQQLHVMERNNWKETQQLIQECEQDHVQRLSNQRSHNKRIQCYSLKQRSLVDAFQKTIRKAEEVLNLVYNKYIFEWQKTQMFPEVRSTNAYSLDEIQTWYESLAAIMWNTKDQIHLTMKSQLREHVSQEINSDLWKVMKDVKDFIKLLLHKAFIVENQPPQVMKMNTRFCATVRLLIDNALIMKIGNPKVTVSIISETQAQQIQSTNAAADFSAGEIENNIGNLQYQLSNKFLANFSNMRLKKINRGNRKLNKLVVDEKFALLFQSSFTLEQEELTVTVWTLSLPAVVIVHVNQEQLAWTTIIWDNLCAKADRKLFEVPNLIPWNRLVEAISMTFSARVGRGLTDENMQYMYRKAYRDKLSFSVSNDQMISFAQFCKDTTPECNYTFWEWLYAALKIIRDHLQVLWVDNTIIGFIHKSTAEKYLAKCVPGTFLLRFTDSVLGGISIAWVHESNDGQRQVLHIQPFTAKDLVVRSLANRICDLGELTYLYPTIPKQEAFGRYTAPAIQKPRSKHYISAEMRTVLIFAPSSNQSSSSTPNAEQSPSTSSNDMFSNEYVLTNLDEIYKFEIENDDMLSIQDYWEQQ
What is the function of this protein?
Signal transduction and activation of transcription.  Plays an important role in the segmental pattern formation in the early embryo by activating specific stripes of pair rule gene expression (By similarity).  The STAT pathway directly participates in immune responses in insects.
What are the official names of this protein?
Signal transducer and transcription activator, Ag-STAT.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: RAB2A_MAIZE
Sequence: MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDNKPIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANANMTIMLVGNKCDLSHRRAVSYEEGEQFAKEHGLIFMEASAKTAQNVEEAFVKTAGAIYKKIQDGVFDVSNESYGIKVGYVVPGQSGGAGSSSQGGGCCS
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic.
What are the official names of this protein?
Ras-related protein Rab-2-A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor.
Protein: CYAA_STIAU
Sequence: MMDAAGRTTQETLARTLESEQGHNALNLSWVRLLATSAVLIVSLYFGRVRGMTDWDVYTPPFAAYWSVTALTLVALYRFERLRRWAGLSLALVDVPAIYWLQHIALPLSPSPGGVAGFTLGLYATLILLSALSLRRTMTLVVTACAAVGEVALQREAHISLGAQLTAVVVLGACAAGACHLLLRIRTLLTTATQQELKRARLGRYFSPAVAERLQDLDRSETSPELREVTLLFADIRDFTSLSERLRPEQVVTLLNEYYGRMVEVVFRHGGTLDKFIGDALMVYFGAPIADPAHARRGVQCALDMVQELETVNALRSARGEPCLRIGVGVHTGPAVLGNIGSATRRLEYTAIGDTVNLASRIESLTKTRDVPILASRATREQAGDTFLWNEMAPASVPGKSQPVAIFTPRNRTPAQQAGAPAAA
What are the official names of this protein?
Adenylate cyclase 1, ATP pyrophosphate-lyase 1, Adenylyl cyclase 1, AC 1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHTB_ECOLI
Sequence: MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIAGLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDIIVMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA
What is the function of this protein?
Conducts the efflux of homoserine and homoserine lactone.
What are the official names of this protein?
Homoserine/homoserine lactone efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_CERS5
Sequence: MARDKTRMKRKERKNIAAGVAHVNSSFNNTKILISDVQGNAISWSSAGTMGFKGSRKSTPYAAQMAAEDAAKKAQEHGMKTIEVEVQGPGSGRESALRALAAAGLNITSIRDVTPMAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y1736_HAEIN
Sequence: MDFNFIEFLGYMATFFVAASFLFKSIVHLRIVNSIGAILFVIYSLIITAYPVALLNAFLVVVNIYQLWRLKQENLSK
What are the official names of this protein?
Uncharacterized protein HI_1736.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARNB_YERPP
Sequence: MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVGTRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSDIHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGSGLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: DNAK_SALA4
Sequence: MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAWLDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDINDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RUVA_BRASO
Sequence: MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKLFGFRSDVEREWFRLLQTVQGVGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVADAISALINLGYGQPQAAAAIAAASRAAGDKAETAQLIRLGLKELAK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: APAG_AGRFC
Sequence: MYRALTRDIEVTVDPYYLEEQSDPDDDRYVWGYKVVIANNSDVPVKLVNRYWHITDQNGQVDEVYGPGVVGEQPQLKPGDSYEYSSGCPLDTPSGLMFGHYEMETENGEVFNVTIPAFSLDSPGLMRVLN
What are the official names of this protein?
Protein ApaG.
Protein: SPRT_PSEAE
Sequence: MPEHLNARVEACYRQAEHFFQRSFPRPTVSFRLRGQKAGVAHLDENLLRFNPQLYRENREHFLEQTVAHEVAHLIAHQLFGPRIRPHGEEWQLIMRGIYGLPPDRCHTYAVKRRATTRYLYRCHCPEHNDFPFSPQRHTLVAKGRRYYCRRCKATLVFTGEVLRE
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCSK9_ATEGE
Sequence: MGTVRSRRLWWPLPLLLLLLRGPAGARAQEDDDGDYEELVLALRSEEDGLAEAPQHGATATFHRCAKDPWRLPGTYVVVLKEETQRSQPERTARRLQAQAARRGYLIKLLHVFHDLLPGFLVKMSRDLLELALRLPHVDYIEEDSYVFAQSIPWNLERITPARYRADEYQPPNGGSLVEVYLLDTSIQSGHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASLRSLRVLNCQGKGTVSSTLIGLEFIRKNQLVQPVGPLVVLLPLAGGYSRVLNAACQRLAKAGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAMARCAPDEELLSCSSFSRSGKRRGERIKAQGGRRVCLAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAGAGMGTRVHCHHQGHVLTGCSSHWEVEDLGTHKPSVLRPRVQPDQCMGHSGASTHASCCHAPGLECKVKEHGLPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDDTCVVRSRDVSTTGNTSEQAVAAVAICCRSRHLAQASQELQ
What is the function of this protein?
Crucial player in the regulation of plasma cholesterol homeostasis.  Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.  Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway.  May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation.  Can induce ubiquitination of LDLR leading to its subsequent degradation.  Inhibits intracellular degradation of APOB via the autophagosome/lysosome pathway in a LDLR-independent manner.  Involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway.  Inhibits epithelial Na(+) channel (ENaC)-mediated Na(+) absorption by reducing ENaC surface expression primarily by increasing its proteasomal degradation.  Regulates neuronal apoptosis via modulation of LRP8/APOER2 levels and related anti-apoptotic signaling pathways (By similarity).
What are the official names of this protein?
Proprotein convertase subtilisin/kexin type 9, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Endosome. Lysosome. Cell surface. Endoplasmic reticulum. Golgi apparatus. Note=Autocatalytic cleavage is required to transport it from the endoplasmic reticulum to the Golgi apparatus and for the secretion of the mature protein. Localizes to the endoplasmic reticulum in the absence of LDLR and colocalizes to the cell surface and to the endosomes/lysosomes in the presence of LDLR. The sorting to the cell surface and endosomes is required in order to fully promote LDLR degradation (By similarity).
Protein: SSB_CAUVC
Sequence: MAGSVNKVILVGNLGADPEIRSLGSGDRVANLRIATSETWRDRSSGERKEKTEWHRVVIFNDNLVKVAEQYLRKGSTVYIEGALQTRKWTDNTGQEKYSTEIVLQKFRGELTMLGGRGGDAGMSSGGGDEYGGGYSGGGSSFGGGQRSQPSGPRESFSADLDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: RHAM_ROSDO
Sequence: MSERYVFRMRLNPGKQAEYQRRHDEIWPELVDLLRAAKISDYSIHLDPDTHVLIGVLIRPQDHGMAALPDHPIMRKWWAHMADIMETGPDDAPIAVPLTPVFHMP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA2_BURVG
Sequence: MNLQGKKITVHDMTLRDGMHPKRHLMTLEQMKSIACGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHSDEEYLGTVIPLMKQAKVSALLLPGIGTVDHLKMAKELGVHTIRVATHCTEADVSEQHIALARKLEMDTVGFLMMAHMNSPEGLVRQAKLMESYGANCVYITDSAGYMLPDDVRARLGAVRDALKPETELGFHGHHNLAMGIANSIAAVECGATRIDAASAGLGAGAGNTPMEVLVAVCDRMGIQTGVDVWAIQDVAEDLVVPIMDFPIRIDRDSLTLGYAGVYGSFLLFAKRAEQKYGVPAREILVELGRRGMVGGQEDMIEDTAITLAKARASKAQKVAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PTH_EHRCJ
Sequence: MFHLLAGLGNPGTQYTLTRHNAGFMVIDAILDKFHFPNFKKKNNALISIGNIESYRVILVKPWTFMNNSGVPIMNIVSLYKIPLDNMIVFHDEVEIDFCTIRVKKSGGNAGHNGLKSIDNFLGKDYWRVRFGIGHPRNKMDLSDYVLSHFHNLNAVNNTISSIVEHITLLLEKNHTTFTDKVRNTLKYEDIPD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_LIMF3
Sequence: MRLMVSGGGTGGHIYPALALIERLKQVEPDTEVLYVGAKRGLETKIVPQAGYRLETMEVQGFRRSLSLENVKTVYLFLKAVAQAKKLIKDFRPDVVLGTGGYVSGAVLYAAAKLGVPTVIHEQNSVVGVTNKFLARYVNEVAIAFEAARSQFPKSSVTMTGNPRAQQVAQRTNSAYSWTEDGLKDGVPTIMIFGGSQGAPRINKAVVEALPSFNEQPYQVIFATGRKRYDDVMGALAGQPIGDNVKVVPYIEDMPDKLPHVDALVSRAGATTIAEVTALGIPTILIPSPYVTANHQVKNAEALVKKGAALMILEDQLDGRSLITQANHLMNDAAVRQKMAANSKAVGHPDASDQLIAVLKKAIADHQK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FTSB_YERPN
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDFVRVKEDVAAQEANNSTLKARNDQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPDQSRRNAGTPSTQNNAQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: RL4_CHRSD
Sequence: MNLNLAGADAGTVEVSDATFGKEFNESLVHQVVTAYFAAGRQGTRAQKTRSEVRGGGKKPWRQKGTGRARAGTIRSPLWRSGGVTFAARPQDYTQKVNRKMYRAAMRSILSELVRQERLVVVDSFEVDAPKTKQLVAKLKDLDLEKALIVTEDIDEKLFLAARNIPYVDVVDVAAADPVSLVAFDKVLVTVSALRKFEEKLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RECA_CLOAB
Sequence: MDNEKLKAIDAAMSQIEKQFGKGAIMKLGEQDILNIDAISTGCLSLDIALGIGGVPRGRVVEIYGPESSGKTTVALHILAEAQKKGGAAAFIDAEHALDPQYARALGVDIDNLVVSQPDTGEQALEIAEALVRSGAIDVIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSINKSKCIAIFINQLREKVGIMFGNPETTPGGRALKFYASVRMDIRKIDTIKQGEEMIGNRVRVKVVKNKVAPPFKQAEFDIMYNEGISREGNIVDVGVKENIIQKSGAWFSYGDIRLGQGRENAKLFFKENIDIRSEVENKIREKYDLPIQKVKNEKPKIEKGTENNTK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT1_TRIRP
Sequence: MSGCNCGSSCNCGDSCKCNKRSSGLNYVEAETTETVILGVGPAKIQFEDAEMGVAAEDSGCKCGSSCTCDPCNCK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 1, Metallothionein-like protein B, MT-B.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.