PharMolix/UniProtQA huggingface dataset:
Protein: MKCA_DICDI
Sequence: MDNNSTLNNITITVASSHNNTTTNSNNNNNNNNGSNSNNNNEQLNTLSNSITSLKSLNISGSGVITNNSEVNTPSEGNITPLPLLSLSDALSPLRELYSCLYVGDIRALMSNQYLKFEENEKIRILGFPEPHLEIDEKTQKYFSYQIIEFESDEDILSIAKSFEQYSQLILGRTPTQPVVIQECCFGLVLASIYFIKYELFSLPQAHDLIGYNDFFGTSKKHSHFEKVDSCTLINDITSYYYNNMSSKRKTTIFSNNISFTNLQTTTPPTTTTTTTTTTTTSSSNNSEQIESTSKNNSSGITSPTSIKPKNKVGLLKKLFNKMDKESSNNNNNKEKVEKIKEKKESKKEREAREAKEEKEREEREKEHQLALKNIPPAELYKHHMEQIQKIQKQQIAELNATSPDGGNDLSNGSNGSKNGNNNNNNNNSNNNNNNNNSNEPNSQHQNHNPITNLMDQELIENYDDGSDRMKNSKTIISPNFESLPDEYKTMVKTWDIKQESVDEHFEIILSLLHFHTKQRFYSSDPTNLPDKPKYYNVGNVCGNCTPPMILDPAGSGQMVVAKSFYKRPFDQICKKPTNEMKKLYTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGGTLAEASNQYPFQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGERIRMCGSPIWMPPEMIQQKQHGYTCDIWSTAICLLELANRNNKLRKNPIKTMFMVGSEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFIQLADNKKKMGKILSSIFLKSIVGI
What is the function of this protein?
Coordinates organism morphology with cellular differentiation during development.  Negative regulator of sporulation, synchronizing encapsulation with culmination.  May have an additional function in prestalk cells.
What are the official names of this protein?
Probable serine/threonine-protein kinase mkcA, MAP kinase cascade A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
Protein: RL29_RICM5
Sequence: MNDLKLLRSKLSTETIEELYKNLNLLKKELFNLRFQQALGELKNTSRFLLVKKSIARIKTELTKRSNSEEY
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: AUR1_ARATH
Sequence: MAIPTETQHQEKEASDASAAAAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQRLPLHKLLEHPWIVQNADPSGIYRV
What is the function of this protein?
Phosphorylates specifically 'Ser-10' of histone H3 in vitro and colocalizes with phosphorylated histone H3 during mitosis.  Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle.  Colocalizes also with gamma-tubulin and function in microtubule organizing centers (MTOCs).  In contrast with the mammalian B-type Aurora, AUR1 has no kinase activity toward 'Ser-28' of histone H3.
What are the official names of this protein?
Serine/threonine-protein kinase Aurora-1, AtAur1, Aurora-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Nucleus membrane. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, phragmoplast. Note=Nuclear membrane in interphase cells, spindle poles at prophase, mitotic spindle from metaphase to telophase and equatorial cell plate at telophase.
Protein: GATB_DESDA
Sequence: MAVYEAVIGLEVHVQLATASKLFCSCPTTFGQPPNSNVCEVCSGMPGSLPVPNGQAIHFATLVGLATGCTINPRSIFARKNYFYPDLPAGYQISQFELPICEHGHLDIEVDGVCKRVGITRIHMENDAGKNIHAQGENISYVDLNRAGTPLVEIVSDPDMRSAAEAVAYLKDLYAIVTYLGVCDGNMEEGSFRCDANVSLRPVGAKEFGTRTELKNLNSFRNVQRAIECEMARQQDLLDDGEKVVQETRLYDAVKNITASMRSKEEAHDYRYFPDPDILPIEISDSDMERWKAELPELPKARAARFVEMTGLPAAEVEVLVQSRGLADFFESAAGLSDARKAANFMLGPLLRECNSRGVNAADPAAWNMKPEALAELVRIVDQGLISSKIANDIFGDLFETGVMPERYVKEKGLVQISDSSALEEAVDAVIAANPAEVEAYRGGKTKLISFFVGQIMRATKGKANPALVNELLAKKLS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: VE6_HPV35
Sequence: MFQDPAERPYKLHDLCNEVEESIHEICLNCVYCKQELQRSEVYDFACYDLCIVYREGQPYGVCMKCLKFYSKISEYRWYRYSVYGETLEKQCNKQLCHLLIRCITCQKPLCPVEKQRHLEEKKRFHNIGGRWTGRCMSCWKPTRRETEV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation.  In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development.  The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).  The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization.  Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis.  E6 also inhibits immune response by interacting with host IRF3 and TYK2.  These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RECR_CLOBL
Sequence: MDFYPIAIEKLIEEFAKLPGIGYKTAQRLTLYVLNLPKEEVKEFSEALVKARGTIKYCSVCGNFTDKDPCAICSNPNRNKSIICVIEQPKDIMSMEKIREYNGVYHVLHGNISPMAGRGPEDIKLKELIRRIDGSVNEVIVATNPNVEGEATAMYISKILKPLGVKVTRIAHGVPVGGDLEYADEVTLAKALEGRIEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: S20A1_MOUSE
Sequence: MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSSPSESPLMEKKSNLKEDHEETKMAPGDVEHRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLPMDLKEETSIDSTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYKQEASTKAATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYIILPV
What is the function of this protein?
(Microbial infection) May function as a retroviral receptor but do not confer infection susceptibility to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B).
What are the official names of this protein?
Sodium-dependent phosphate transporter 1, Gibbon ape leukemia virus receptor 1, GLVR-1, Leukemia virus receptor 1 homolog, Phosphate transporter 1, PiT-1, Solute carrier family 20 member 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IPPK_USTMA
Sequence: MPPTRFQPSHQTPFKSTISTSQQSRIFHSPLQAGATANPVSISISDIDPSEWKYHAEGGKNVLLSFDPVGGIQAGKSPFATLTCTYALRIPKSLPSKSESNQEDEQEAEQFTRHVVQPLLGDATVLPKCMRIPIVTARDRHVIDMLSARIEMQRPAARRTHPARIRSEALSYIYAVEDVAAPVSVSPSAQRAVLCVEIKPKWGFLARIDSIPPSSPNVEIKARYSRYRMHRVAKHAAADHAGQMSIEQFERLYDPVDLYSCDSERKQKAIKALWDDWIDTKGKTNNLRLFWNGAVVDPQDSVTLEAIAQFLGTDNSVQGRLKGALTQHLDKELSKRVLGENDEWSTVSVLSRLAHLQSALDPLDVEGLAHLWLRRTQSHVLGQASSDVDLPPALTRNLAAAQLAAMLDSFLSGTTAEVSLEDAVQAFLVSASFKDCSMLLRFHQTESGVQGETKLVDLDSKPFAKLSSMQQTDSEVCAAFLAWLSQLDRSPAASVAP
What is the function of this protein?
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
What are the official names of this protein?
Inositol-pentakisphosphate 2-kinase, Inositol-1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase.
What is the protein family that this protein belongs to?
Belongs to the IPK1 type 2 family.
Protein: PCF_BACSU
Sequence: MQDLLFEYKRTLKQTRIQYKPLAEADESVLSAEELKDKKIIRNMITDLEYVTEWLEKGRQPGIRRAIDRRDVYQRLMIKDPRIIESFSSAMMFEPDGQVSEEDRDRIREALALLTDREKEMFLLHKVECFSYERIADLLGVKKSTVQTTIKRASLKMQRQQEEMNRSLA
What is the function of this protein?
Positive regulatory protein that acts at the late promoter PL.
What are the official names of this protein?
Positive control factor.
Protein: TGBR3_PIG
Sequence: MTLHCVVALFALISSCLATAGPEPGVQCALSPVNASHPVQALMESFTVLSGCASRGTMGRPQEVHVLNLRAADQGPGQRQSEVTLHLNPISSVHIHHKPVVFLLNSPQPLVWHLKTERLAVGVSRLFLVSEGSVVHFSSGNFSLSAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCSIGKNFLSLNYLAEYLQPKPAEGCVVSGRPQEKEVHIIELIAPNSNPYSAFQVDIIIDIRPSRKDPELVKNLILILKCKKSVNWVIKSFDVKGNLKVLAPNSIGFGRESERSMIMTKSVRDDIPSTQEKLLRWALDNGYSPVTSYTVAPVANRFHLRLENNEEMRDEEVHTIPPELQILLDPGALPVLDHPPSGEGAARHGGLPFPFPYIPRRGRQDGGKDRLPRPKDPVVPSIQLLPGPREPQEAQGSRDVALSVRCDSEKMLVAVEKDSFQASGYPGLELTLLDPTCKAKTNGTHFILESPLDGCGTRHRRSAPDGVVYYNSIVIQAPPSGDSSGWPDGYEDLESGDNGFPGDVDEGDVALSSRPELVVFNCSLRPARHPSRAQDPPTRNVTFSMDLYTTDLFLAPAQGVFSVAENGHVYVEVSVTKADQELGFAIQTCFISPYSNPDRMSDYTIIENICPKDESVKFYDPKRVHFPIPQAETDKKRFSFVFKPVFNTSLLFLQCELTLCTKREKEPQKLPKCVLPDEACTSLDASMIWAMMQNKKTFTKPLAVIHHEVQFKGPSTKESNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGDSAGRQPVPTSPPASENSSAAHSLGSTQSTPCSSSSAA
What is the function of this protein?
Binds to TGF-beta.  Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
What are the official names of this protein?
Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Secreted, extracellular space, extracellular matrix. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Protein: APEB_PSEMY
Sequence: MREELIQGLLDFLNASPTPFHATTSLAMRLEAAGYRHLDERAPWHTEAGGRYYVTRNDSSIIAFKLGKRPVVEGGIRLVGAHTDSPCLRVKPSPELQRQGYFQLGVEVYGGALLAPWFDRDLSLAGRVTYRRDGKVESQLIDFYQPIAVIPNLAIHLNREANMGWAINAQNELPPILAQLASSETADFRALLAEQLAMEHDFNPDAVLDYELSFYDTQSAAIVGLNQDFIASARLDNLLSCYAGLQALIDSSDEETCVLVCTDHEEVGSCSACGADGPFLEQVLRRVLPEGDDFVRSIQRSLLVSADNAHGVHPNYADKHDGNHGPKLNAGPVIKINSNQRYATNSETAGFFRHLCLENEVPVQSFVVRSDMACGSTIGPITASQLGVRTVDIGLPTFAMHSIRELAGSHDVDHLVKVLTAFYSSPELP
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: HEMA_I82A5
Sequence: QDLPGNDNSTATLCLGHHAVPNGTIVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGRDCTLIDALLGDPHCDVFQDETWDLFVERSNAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPASGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSVMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCAVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RGP1_MAIZE
Sequence: MAGTVTVPGSSTPSTPLLKDELDIVIPTIRNLDFLEMWRAFFQPYHLIIVQDGDPTKTIKVPEGFDYELYNRNDINRILGPKASCISFKDSACRCFGYMVSKKKYIYTIDDDCFVAKDPSGKDINALEQHIKNLLSPSTPFFFNTLYDPYREGADFVRGYPFSLREGAHTAVSHGLWLNIPDYDAPTQLVKPKERNERYVDAVMTIPKGTLFPMCGMNLAFDRDLIGPAMYFGLMGDGQPIGRYDDMWAGWCVKVICDHLSLGVKTGLPYIWHSKASNPFVNLKKEYKGIFWQEDIIPFFQNVTIPKDCDTVQKCYIYLSGQVKEKLGTIDPYFVKLGDAMVTWIEAWDELNPSTPAAANGKAK
What is the function of this protein?
Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides (By similarity).  Was initially shown to possess an autoglycosylating activity which is dependent on the presence of UDP-glucose and manganese (Ref. 4, PubMed:8832094, PubMed:9620435).
What are the official names of this protein?
Probable UDP-arabinopyranose mutase 1, Amylogenin, Golgi-associated protein se-wap41, Reversibly glycosylated polypeptide, RGP, UDP-L-arabinose mutase 1, UDP-glucose:protein transglucosylase, UPTG.
What is the protein family that this protein belongs to?
Belongs to the RGP family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell junction, plasmodesma. Golgi apparatus. Note=Cell wall-associated, with highest concentrations on plasmodesmata. Also located in the Golgi apparatus.
Protein: FLGC_BUCAI
Sequence: MSLLNIFNIAGSAMIAQSQKLNVIASNLANMDSTIYKNGKFYPYIAKQVVFSLDTAKNSKIGGVKISAIIDDPSPMKLIYDPNNPMANNKGYILASNVNPITEMVNNIAAARSYQANIEVLKTAKSMIMKTLTISE
What are the official names of this protein?
Flagellar basal-body rod protein FlgC.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CADH1_ARATH
Sequence: MSSSESVENECMCWAARDPSGLLSPHTITRRSVTTDDVSLTITHCGVCYADVIWSRNQHGDSKYPLVPGHEIAGIVTKVGPNVQRFKVGDHVGVGTYVNSCRECEYCNEGQEVNCAKGVFTFNGIDHDGSVTKGGYSSHIVVHERYCYKIPVDYPLESAAPLLCAGITVYAPMMRHNMNQPGKSLGVIGLGGLGHMAVKFGKAFGLSVTVFSTSISKKEEALNLLGAENFVISSDHDQMKALEKSLDFLVDTASGDHAFDPYMSLLKIAGTYVLVGFPSEIKISPANLNLGMRMLAGSVTGGTKITQQMLDFCAAHKIYPNIEVIPIQKINEALERVVKKDIKYRFVIDIKNSLK
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 1, AtCAD1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: KLF16_MOUSE
Sequence: MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPAAGLDVRATRREATPPGTPGAPPPPATAPGPGGATAAPHLLAASILADLRGGPVVATAASTAGGTSPVSSSSAASSPSSGRAPGAAKSHRCPFHGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCTKRFTRSDHLTKHARRHPGFRPELLRRPGARSVSPSDSLPCSLAGSPTPSPVPSPAPAGL
What is the function of this protein?
Transcription factor that binds GC and GT boxes in the D1A, D2 and D3 dopamine receptor promoters and displaces Sp1 and Sp3 from these sequences.  It modulates dopaminergic transmission in the brain by repressing or activating transcription from several different promoters depending on cellular context.
What are the official names of this protein?
Krueppel-like factor 16, Basic transcription element-binding protein 4, BTE-binding protein 4, Dopamine receptor-regulating factor, Transcription factor BTEB4.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPAM1_RAT
Sequence: MARDLIGPALPPGFKERATVEDQERDPSPVAGPALPPNYRSSSSDSSDSNEDSSSLSEEGNQESEEDDAGPTAKKQRRNQDRDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSPQKNDKGRENPGQVSPFFNSEEAESGEDEDIVGPMPAKGPVDYSVTAEFEKRAQRMKEKLTKGDDDSPKPVTRESWMTELPPEMKDFGLGPRTFKRRADDKSGDRSVWTDTPADRERKAKEIQEARKSLSKKDEENMLSGRDKRLAEQVSSYNESKRSESLMDIHHKRLKTKAAEDKNRHQERTPFDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHGKGNMFL
What are the official names of this protein?
GPALPP motifs-containing protein 1.
Protein: PXPA2_AGRFC
Sequence: MKIDLNSDMGEGFGPYRLCDDEAMMKIVSSANIACGFHGGDPDTMARMVRLAKANGVGIGAHPGLPDRAGFGRREIPFQPDELRQQMLYQLGALMAIAGAEGMKVGHFSFHAAMGNMVNRDPVLADLMMNAIATVDPRLVVFVTPESEIERAAKRAGLKTLALFLADRAYDAEGRLVARGLPGALVKDETSVRARVRRFLTHGQVEAIDGTIIAMPAHSILVHSDTPGSLELARIIRSEIEASGATLAPAAEHAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A 2, 5-OPase subunit A 2, 5-oxoprolinase (ATP-hydrolyzing) subunit A 2.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: GLND_NEIM0
Sequence: MPANLSSALETFKRQRDAAEAHYLKANRVSVFFREYTAAVETLLAALWVEHFQNSALCLMAVGGFGRGELYPCSDVDLAVVSPAPLSDGIQEQIARFVQTLWDCKLMPSVKSGSVGELCESVRDDITGDTAFLEARFLFGNRQTADELAKKMNAQRNVAAFVEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLATDLPDLLKQRILTRAEAGMLSHGYRRLAHIRIHLHLNAKRAEDRLLFDLQPQVAESMGYEGLNLRRQSEELMRVFYRAIKTVKQLGGILTPMLQSRVSSTPLRVTLRIDDDYIQVNNQIAARHTDIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNSENRHRFAGFFRNGNGLTQTLRFLNLYGVLGRYLPAWEKIVGLLQHDLFHIYPVDDHILTVVRNVRRLALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAIQGIADARQFAADHFLTEEESDLLAWLVENHLLMSTVAQKEDIQDPSVLDAFCKRVQTHERLSALYLLTISDIRGTNPKLWNAWRASLLESLFHAAGRYLTGNGGNPHTLFGRRRQEAADLLTRAAVPEKQQKKLWNALGSAYFARHQSREILWHAANLVHDFETPIVRSRILPQSDSFQVMVFMPNGPRLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAELNSFIHGHTVAEISSHSRRISRRSRYMPIAPSITITPEEDYPDWYSVEITAVNRPFLLADMAEVFFAHNVSLRYAKISTLDERAEDSFTVFSPDLNNPKIQSSLKQTLLEQLS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: IF4A6_TOBAC
Sequence: HVVVGTPGRVFDMLRRQSLRPDNIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGIFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRSGRFGRKGVSINFVTKDDERMLFDIQKFYNVVIEELPANVADL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-6, eIF-4A-6, ATP-dependent RNA helicase eIF4A-6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: APC_XENLA
Sequence: MAAASYDQLVKQVEALTMENTNLRQELEDNSNHLTKLETEATNMKEVLKQLQGSIEDEAMASSGPIDLLERFKDLNLDSSNIPAGKARPKMSMRSYGSREGSLSGHSGECSPVPVGSFQRRGLLNGSRESAGYMEELEKERLLLIAEHEKEEKEKRWYYAQLQNLTKRIDSLPLTENFSMQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRVQTRVGKIHQIEEEILRIRQLLQSQVAEAAERTPQSKHDAGSRDAEKLPDGQGTSEITASGNVGSGQGSSSRADHDTTSVMSSNSTYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARASGSAALDNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLINDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKSCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALDVKKESTLKSVLSALWNLSAHCTENKADICSVDGALAFLVSTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEGLWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSVPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKTTHRNKQRHKQNLCSEYALDSSRHDDSICRSDNFSIGNLTVLSPYINTTVLPGSSSPRPTMDGSRPEKDRERTAGLGNYHSTTESSGNSSKRIGIQLSTTAQISKVMDEVSNIHLVQENRSSGSASEMHCMSDERNSQRKPSSNHPQSNPFTFTKAESSTRGCPVAFMKMEYKMASNDSLNSVSSTEGYGKRGQVKPSVESYSEDDESKFFSYGQYPAGLAHKIQSANHMDDNDTELDTPINYSLKYSDEQLNSGRQSPTQNERWSRPKHIIDSEMKQSEQRQPRTTKTTYSSYTENKEEKHKKFPPHFNQSENVPAYTRSRGANNQVDQSRVSSNLSNNSKASKPHCQVDDYDDDKTTNFSERYSEEEQQEDETERQNKYNIKAYASEEHHGEQPIDYSRKYSTDVPSSAQKPSFPYSNNSSKQKPKKEQVSSNSNTPTPSPNSNRQNQLHPNSAQSRPGLNRPKQIPNKPPSINQETIQTYCVEDTPICFSRGSSLSSLSSAEDEIEGRERNSRGQESNNTLQITEPKEISAVSKDGAVNETRSSVHHTRTKNNRLQTSNISPSDSSRHKSVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSGSSLDSFESHSIASSIASSVASEHMISGIISPSDLPDSPGQTMPPSRSKTPPPPQTVQAKKDGSKPIVPDEERGKVAKTAVHSAIQRVQVLQEADTLLHFATESTPDGFSCASSLSALSLDEPYIQKDVQLKIMPPVLENDQGNKAEPEKEFIDNKAKKEDKRSEQEKDMLDDTDDDIDILEECIISAMPRKPSRKNKKVPQPTPGKPPPPVARKPSQLPVYKLLSSQNRLQTQKHVNFTHSDDMPRVYCVEGTPINFSTATSLSDLTIESPPSEPTNDQPNTDSLSTDLEKRDTIPTEGRSTDDTDASKPLNPTTVLDEDKAEEGDILAECIHSAMPKGKSHKPYRVKKIMDQINHTSAATSSGNSRSMQETDKNKPTSPVKPMPQSIGFKERLKKNTELKLNPNSENQYCDPRKPSSKKPSKVANEKIPNNEERTKGFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFEDDDIDLSKEKAELRKEKGTKDTDQKVKYKHENRAINPMGKQDQTGPKSLGGRDQPKALVQKPTSFSSAAKGTQDRGGATDEKMENFAIENTPVCFSRNSSLSSLSDIDQENNNKETEPLKQTGTSETQLGLRRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKRKPSKIKNEVGKSRSNSVGGILAEEPDLTLDLRDIQSPDSENAFSPDSENFDWKAIQEGANSIVSRLHQAAAAGSLSRQGSSDSDSILSLKSGISLGSPFHLTLDKEEKTITSNKGPKILKPAEKSALENKKTEEEPKGIKGGKKVYKSLITGKSRSSSDFSSHCKQSVQTNMPSISRGRTMIHIPGVRASSPSTSPVSKKGPVFKNVPSKGSNENPSSSSSPKGTKPLKSELVYGSRPSSTPGGSSKGNSRSGSRDSASSRPSPQPLSRPLQSPGRNSISPGKNGISPPNKFSQLPRTTSPSTASTKSSGSGRMSYTSPGRQLSQPNLSKQSGLPKTHSSIPRSESASKSLNQNVNTGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEESASFESLSSSSRADSPPRSQTQTPALSPSLPDMALSTHSIQAGGWRKMPPNLNPAAEHGDSRRRHDISRSHSESPSRLPITRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQQVCSFPGPRSECSSSAKGTWRKIKESEILETPSNGSSSTIAESNCSLESKTLVYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNSPPVIDNVLDQGQKEEAAKDCHTRHNSGNGNVPLLENRQKSFIKVDGLDTKGTDPKSLINNQQETNENTVAERTAFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSNGENSTSRPSQIPTPVTNSTKKRDSKTETTDSSGSQSPKRHSGSYLVTSV
What is the function of this protein?
Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator.
What are the official names of this protein?
Adenomatous polyposis coli homolog, Protein APC.
What is the protein family that this protein belongs to?
Belongs to the adenomatous polyposis coli (APC) family.