PharMolix/UniProtQA huggingface dataset:
Protein: MARE2_BOVIN
Sequence: MPGPTQTLSPNGENNNDIIQDNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPASKPGSTPSRPSSAKRASSSGSASRSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDVLYASDEHEGHPEEPEAEEQVHEQQPQQQEEY
What is the function of this protein?
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes.  May play a role in cell migration (By similarity).
What are the official names of this protein?
Microtubule-associated protein RP/EB family member 2.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules (By similarity).
Protein: FBID_ROSCS
Sequence: MDLYAIVPVKELRHAKQRLAHALDAHERQELSLAMLGDVLAALSQSQVRRVTVISRDTAAYQIATAYGAVIAVDQTSDLNAALYQAAVDVPDDAAILIVPSDVPLLRADDVMMLAAQPGVAITPAHDGGTNLLLTPAIRGWTFLFGPDSFVRHCAEARRRGWTVHVVRLPHLERDIDEVDDLVWLAQQPGHTAAQRLAREFLMRKGARIW
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: RBP47_NICPL
Sequence: MNGGDMNQQQQQQQQQHQQQQQQWLAMQQYQQQWMAMQYPAAAMAMQQQMMYGQQYMPYYQQHQQQQKMQQSPTQIQSSSEDNKTIWIGDLQQWMDESYLHSCFSQAGEVISVKIIRNKQTGQSERYGFVEFNTHAAAEKVLQSYNGTMMPNTEQPFRLNWAGFSTGEKRAETGSDFSIFVGDLASDVTDTMLRDTFASRYPSLKGAKVVVDANTGHSKGYGFVRFGDESERSRAMTEMNGVYCSSRAMRIGVATPKKPSAHEQYSSQAVILSGGYASNGAATHGSQSDGDSSNTTIFVGGLDSEVTDEELRQSFNQFGEVVSVKIPAGKGCGFVQFSDRSSAQEAIQKLSGAIIGKQAVRLSWGRSPANKQMRTDSGSQWNGGYNGRQNYGGYGYGASQNQDSGMYATGAAYGASSNRYGNHQQPVS
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
What are the official names of this protein?
Polyadenylate-binding protein RBP47, Poly(A)-binding protein RBP47, RNA-binding protein 47, NplRBP47.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding RBP47 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasmic granule. Note=Relocalizes from nucleus to cytoplasmic stress granules (SGs) under heat stress.
Protein: TFE_NANEQ
Sequence: MPTSKQIINKKQDEVSDIYGKEMIRVIRSLLKHKIIDTESLSKKTGYSINTVRRALYTLQKMGIVRYINKEDKTLWQLLETDYEKILDTLLEPYKKEEKAETGELLFICPKCGRKYTLDEAEMYEFRCPEDGTLLVANQ
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: DEOB_SHISS
Sequence: MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGHWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKATGLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAVGLELFDRRLPELMSLLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLAKYFGTSDMEYGKAMF
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAD3_MOUSE
Sequence: MSWLFGIKGPKGEGTGPPLPLPPAQPGAEGGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLTEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLLGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSQTNKPPHPSLLSC
What is the function of this protein?
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level.  May play an important role in mitochondrial protein synthesis.  May also participate in mitochondrial DNA replication.  May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.  Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.  Involved in mitochondrial-mediated antiviral innate immunity.
What are the official names of this protein?
ATPase family AAA domain-containing protein 3, AAA-ATPase TOB3.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (By similarity).
Protein: GLXK2_ECOLI
Sequence: MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQALAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
What are the official names of this protein?
Glycerate 3-kinase, D-Glycerate-3-kinase, Glycerate kinase 2, GK2.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-1 family.
Protein: V014_FOWPN
Sequence: MEVFEAIESGCVSDVIKALKGNDSDPNMVNEYGCSLLHCAVENGNTEIARILLLEGANPDLYTESTPTALHRAVILRHYDIVNLLMEFNVDPDNYENHESRTPLEYAVKLNDVKMTKTLLDYGADAEDIYRFNCPINDAAANGNLEICKLLIDAGARINSRSMGSVYTIHHAIRSGNYELVVELLSRGALPDVEDELSFSSLHHAVMEGSADMVLTLLEHGASVDVQDFCGRTPLFLAANASELDIVKVLLDFWADTSVSSGRNTPLSVCDLNSDTGIEIAKQIISTMVINTEYKYHKVINEEARRNDLEIIESNNEMKDWKDSCIEEVEKMRKTTLGSDRRSLLDLCLNCDDNAIAKCLNCISCEGFFIYRQLIEYTIERGLLRHESLDKALDVMEKAFEKNRNVKDNGLKDWSDLPLGIKYDILEKIDEEDLPYC
What are the official names of this protein?
Putative ankyrin repeat protein FPV014.
Protein: SOX13_MOUSE
Sequence: MSMQSPVSVQLAPDSASTMVNCTIKSEEKKEPCHEAPQGAAPAVETQPGDPALASQDATNAKAPPQDCASPESSGSPEPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLGRSNVEAKDVKGTQESLAEKELQLLVMIHQLSALRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRSGVAAHHPLQEPPQPLNLTAKPKVPELPNTSSSPSLKMNSCGPRPASHGAPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPNTPFRKDLISLDSSPAKERLEESCVHPLEEAMLSCDMDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRLRVGEYKALMRTRRQGARQSYTIPPQAGQAQVSSDILFPRAAGLPLARPLVEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGDEKSDEELVVLTD
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed:9524265, PubMed:9421502).  Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (PubMed:26525805).  Binds to the gene promoter of MBP and acts as a transcriptional repressor (PubMed:26525805).  Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (PubMed:17218525, PubMed:23562159, PubMed:30413363).  Required for the differentiation of Vgamma2-positive gamma-delta T-cells, a subset of IL17A expressing gamma-delta T-cells (PubMed:23562159).  Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (PubMed:23562159).  Promotes brown adipocyte differentiation (PubMed:27923061).  Inhibitor of WNT signaling (By similarity).
What are the official names of this protein?
Transcription factor SOX-13, SRY (Sex determining region Y)-box 13, mSox13.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LGT_STRPM
Sequence: MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXH_ECO81
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHDQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: QUEA_CAMJ8
Sequence: MNKDLLLSSYDYTLANELIANYPTNPKEDARLLVFDRKNKEIFHTTFKNLQDFLPNCAIFFNDTKVIKARIYGNKVSGGKIELFLHQPFLNSHNPLFLAQIKGRVKKDEILYFKKDLKIRVVELLNDGLRKVQFFQNDKTLDTSNLYNLLDKIGHIPLPPYIKREDEKSDLKDYQSIFAKNLGAVAAPTASLHFSETMLENLRKKHEIYHLTLHVGAGTFKSVECENIQEHKMHSEFFNIPQQACEIIDSKQAILGVGTTVTRTIEYYARTKTKSGFCDLFLHPQNPPIRQNHLLTNFHLPKSTLIMLVSAFIGREQCLKLYELAIKEKYRFYSYGDAMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_ECOSE
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEIRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_HETP5
Sequence: MMRSTLSLLQKCRLPNNNGSLLSFKNNQVVNQTALFSMKSNQQYRFYSTDVKDLAPLIKELRNRTSAPLKDCKEALIQNKNDIEKATSWLHEKGKSTANKFADRAVVEGTISIVVNNGKAVILEMNSETDFVSRGETFRALADQISRATLESNLLAQSLAEIKPDTIAPQPASGSTVADLIVGTVAKLRENIRLRRVHAIDASNQPNTIVAGYAHDPSGTNQFGRLGSLVQLQYEGGQPDIAALNQLARNIAVHIVGVGPSYVSIESVPKVLLDEAIANKRHPNSLYDEVVLLEQKYISGEDNETVKAAVQRISKQLKTNITIKSFVRYSVGEGMEKKVENYGAEVMEKINKAK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
Protein: OBRG_CHICK
Sequence: MAGIKALVGLSFSGAIGLTFLMLGCALEYYGVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAIKWGACGLVLAGNAVIFLTILGFFLVFGRGDDFSWEQW
What is the function of this protein?
Involved in protein trafficking.  May be involved in the down-regulation of membrane protein levels (By similarity).
What are the official names of this protein?
Leptin receptor gene-related protein, Endospanin-1, OB-R gene-related protein, OB-RGRP.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endosome membrane.
Protein: CPFC_MYCA1
Sequence: MDFDAVLLLSFGGPEGPEQVRPFLENVTRGRGVPPERLDHVAEHYLHFGGVSPINGINRALIEQLRAAQALPVYFGNRNWEPYVEDTVKVMRDNGIRRAAVFTTSAWSGYSSCTQYVEDIARARAAAGPGAPELVKLRPYFDHPLFVEMFAGAIADAAAKVPAGARLVFTAHSVPVAADERVGPRLYSRQVAYAARLVAAAAGYAEHDLVWQSRSGPPQVRWLEPDVADHLRALAESGTPAVIVCPIGFVADHIEVVWDLDEELRAQAESAGMLMARASTPNAQPRFARLAADLIDELRCGRTPARVTGPDPVPGCLASVNGAPCRPPHCAAQATG
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAS_DROME
Sequence: MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
What are the official names of this protein?
G protein alpha s subunit, Adenylate cyclase-stimulating G alpha protein, Guanine nucleotide-binding protein G(s) subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
Protein: GLCU_BACCR
Sequence: MMDIFLAILPAIFWGSIVLFNVKLGGGPYSQTLGTTFGALIFSIVVYIFMKPVLTPTVIGVGVVSGLFWALGQANQLKSIDLMGVSRTMPISTGLQLVATTLFGVIVFHEWSTTISVVLGILALVCIIIGVILTSLQSEEEKNAEQAANFKRGIVILLISTVGYLVYVVVIRLFNVDGWSALLPQAVGMVLGGILLTFKHHPFNKYAIRNIIPGLIWAAGNMFLFISQPRVGVATSFSLSQMGIIISTLGGILILGEKKTKRQLTGIVVGIVFIIAAGIMLGIAKS
What is the function of this protein?
Involved in the uptake of glucose.
What are the official names of this protein?
Probable glucose uptake protein GlcU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEPRM_MYCTU
Sequence: MSSTVIDRARPAGHRAPHRGSGFTGTLGLLRLYLRRDRVSLPLWVLLLSVPLATVYIASVETVYPDRSARAAAAAAIMASPAQRALYGPVYNDSLGAVGIWKAGMFHTLIAVAVILTVIRHTRADEESGRAELIDSTVVGRYANLTGALLLSFGASIATGAIGALGLLATDVAPAGSVAFGVALAASGMVFTAVAAVAAQLSPSARFTRAVAFAVLGTAFALRAIGDAGSGTLSWCSPLGWSLQVRPYAGERWWVLLLSLATAAVLTVLAYRLRAGRDVGAGLIAERPGAGTAGPMLSEPFGLAWRLNRGSLLLWTVGLCLYGLVMGSVVHGIGDQLGDNTAVRDIVTRMGGTGALEQAFLALAFTMIGMVAAAFAVSLTLRLHQEETGLRAETLLAGAVSRTHWLASHLAMALAGSAVATLISGVAAGLAYGMTVGDVGGKLPTVVGTAAVQLPAVWLLSAVTVGLFGLAPRFTPVAWGVLVGFIALYLLGSLAGFPQMLLNLEPFAHIPRVGGGDFTAVPLLWLLAIDAALITLGAMAFRRRDVRC
What is the function of this protein?
Probably part of the ABC transporter complex Rv1217c-Rv1218c involved in the resistance to a wide range of structurally unrelated drugs (PubMed:23143285).  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Multidrug efflux system permease protein Rv1217c.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3395_BACCR
Sequence: MSTSNLNEISKQILKEEETLQFSSFTNEDALQLGLFIVETAKREGKLIAVDITKNGVQLFHFKMTGTNAENTKWIERKKRVVSLHDRSSYYMQIQSEITGISYNEKYLLDTSEYAAFGGCFPIRIKNVGVIGMITVSGLPPEEDHELVVRAVKNHLNQ
What are the official names of this protein?
UPF0303 protein BC_3395.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: RSSA_CRIGR
Sequence: MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVRRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTAAQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTEWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.  Also acts as a receptor for several other ligands, including the pathogenic prion protein, Sindbis virus, and bacteria.  Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity).
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus. Co-localizes with PPP1R16B in the cell membrane.
Protein: GSKIP_HUMAN
Sequence: METDCNPMELSSMSGFEEGSELNGFEGTDMKDMRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLELTEAGLKVVGYAFDQVDDHLQTPYHETVYSLLDTLSPAYREAFGNALLQRLEALKRDGQS
What is the function of this protein?
A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets (PubMed:27484798, PubMed:25920809, PubMed:16981698).  The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively (PubMed:27484798, PubMed:16981698).  Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B (PubMed:25920809).  During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (PubMed:19830702).
What are the official names of this protein?
GSK3B-interacting protein, GSKIP, GSK3beta interaction protein.
What is the protein family that this protein belongs to?
Belongs to the GSKIP family.
Protein: TRMJ_PHOLL
Sequence: MLENIRIILVETSHTGNMGSTARAMKTMGLTNLYLVNPLVQPDSHAIALSAGASDVIGHATIVDSLDKALAGCGLVIGTSARSRTLSWPMVEPRECGERSVQQAEHASVAIVFGRERVGLTNEELQKCHYHLNIPTNPEYGSLNLAMAVQLVSYEIRMAYLARQDKTEQKTDEVEYPLADDMERFYHHLECVLNDSGFIRKAHPGQIMNRLRRLFTRARPEMQELNILRGILSSVEKWAKK
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPA2_ARV
Sequence: MPFWVEVRINNLDEGDISALENNFTQNFNNLIDQNKEIIKYIIQKVKTQSYLEGKLHPFYYINLIDTNDLHKPCFLTKFGLKSRFTREEKGYIVIEGHYH
What are the official names of this protein?
Protein alpha-2.
Protein: RRF_RICPR
Sequence: MEKDNLKKILQEKMEKAIKVLGNELKGLRTGRASINFLDSVTVEAYGSKIPLSQVASLSTPDARTINVQVWDKSMVSSVEKGITIANLGLTHATDGQLIRLPIPSLTEERRKELVKLAHKYGEETKISLRNIRRDGIEELKKLEKDNIIVKDEYHNLSEQIQKLTDEYSSKVDSAIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PSEPF
Sequence: MKADIHPNYPEVAVTCSCGNKFETRSTFGKALAIDVCNECHPFYTGKQKTLDTGGRVQKFADRFGAFGAKKA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: YCGL_SALPC
Sequence: MRQVTIPLIQSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEALMKGFGQPQLAMMLPLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSPADR
What are the official names of this protein?
Protein YcgL.
Protein: FOLD_SHIBS
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.