PharMolix/UniProtQA huggingface dataset:
Protein: LSRC_YERPG
Sequence: MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVTVGMALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVATLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSISPIGWLTMLLILAMAWLLGKTAFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGLEMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGVLVFDGRLRCAVERNIRQQKYARFTAQAIISDKKPTVSDNNPAASNKKKAAL
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrC, AI-2 import system permease protein LsrC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_FRAP2
Sequence: MQIVDQMRDQAFEELNLVNDKKSLDDIRVKYLGKKGELTGMMRLIATLPNEEKPKLGQAVNIAKEALQNAINEKLAKFEEAELNEKLASEKIDVTLKGVGQNQGSLHPVTKTLNRIEAFFKQNGFAVEVGPEIESDYYNFETLNIPSHHPARAMHDTFYIDDTHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLKVRFRPSYFPFTEPSAEADMECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSENYQGFAFGMGVERLSMLRYGIDDLRMFFENDLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O166_CONIM
Sequence: MKLTCMMIVAVLFLTAWIFITADNSRNGIENLPRMRRHEMKNPKASKLNKRGCREGGEFCGTLYEERCCSGWCFFVCV
What are the official names of this protein?
Conotoxin 6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MED4_CAEBR
Sequence: MTESDERSLRDLLLESADDLENVLKMIIDTLINREKSVMLKSGESVTNIVRLFDAKQESVRKLLQKVPEFQERESLIRTLKAHVEKRDEVIQQVENNLKACEVALTRSCFHANQKVKKMNEAALRPVNSETLIKLSHQISKHNSVSAPLTWQIGDPSRPFPQEHEFRTGQLLNPKIQSSGPQILLGKSSAQKPIIASPSASSSNGGTAPTRTVGTPLVNSATNGDYSPRTGYGAEETSPIQEQVLLGVTPNEKQWQNPPMPGAATSSQSPLSGAPQSPSSPSVKLKISGIPNRPGDIDQVQEVRDVEQMSSDSSNSSDSSDDEGSSKKTRGRNK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IL23A_RAT
Sequence: MLDCRAIILLWLLPWATQGLAVPRSSSPDWAQCQQLSRNLCTLAWSAHTPVGQMDLLREEGEEETKSDVPRIQCGDGCDPQGLKDNSQFCLQRIRQGLVFYKHLLDSDIFTGEPSLLPDSPVDQLHTSLLGLSQLLQPEDHHWETQQMPRLSPSQQWQRSLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA
What is the function of this protein?
Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.  Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.  This process leads to activation of several pathways including p38 MAPK or NF-kappa-B and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A.  In turn, participates in the early and effective intracellular bacterial clearance.  Promotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells.
What are the official names of this protein?
Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted upon association with IL12B.
Protein: RS19_ANAPZ
Sequence: MSRSVKKPPFCAPHVLRLANRVIASNRTSVVINIHSRSSVILNKFVGLTFGVYNGKTYVPVKVTDNIVGRKFGEFSPTRRFLGHAGDKKVSRKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RRF_LEPIC
Sequence: MASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISVPEPRMLVISPYDKGIMKDIEKAIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKSKSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQKITDSYIDKISALTAEKEKEITTI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BRUME
Sequence: MARVKRGVTAHAKHKKVLDQAAGFRGRRKNTIRTAKAAVDRSKQYAYRDRKNRKRSFRALWIQRINAAVREQGLTYGRFIDGLAKAGIEIDRKVLSDIAIHEPEAFAALVASAKKALEYLKNTSMPNAFEGAVR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CYOE2_PSEA7
Sequence: MKLKRYLLVAKPGIIFGNLIAVAGGYFLAARGSVEPMLLLATVIGLSLVVASGCVLNNCIDRDIDRHMERTRGRVTVTGQISLKAALAHGLVLGVAGFGLLWWRTNPLTTALAGFGYFVYVGLYSLWFKRRSQYGTLVGSLSGAMPPVVGYCAVTGQFDAGAASLLAIFCLWQMPHSYAIAIFRLKDYEAAGIPVLPVARGIAVTKIHIVLYILAFMAATLALCLGGYAGYGYLLVAVAVSLWWLAIALTGYWTADDRLWARKLFAFSIVAITALSVMMSIDFQVAPATHLVASLP
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BMPB_BORGP
Sequence: MRIVIFILGILLTSCFAGNEIESGSSKIKISMLVDGVLDDKSFNSSANRALLRLEEDFPENIEKVFSSAASGVYSSYVSDLDNLKMNGSDLIWLVGYMLTDASLSVSLENPKISYGIIDPVYSDDVQIPKNLIGVVFRIEQGAFLAGYIAAKKSVSGKIGFIGGVKGDIVDAFRYGYEAGAKYADKGIEIVSEYSNSFSDVNIGRAIANKMYAKGIDIIHFAAGLAGIGVIEAAKELGDGYYVIGADQDQSHLAPRNFITSVIKNVGDALYLVTSEYLKNNNTWEGGKIIQMGLRDGVVGLSNANKFEYIKVIERKIVNEEIIVPYNHEGYEIFIKQILKL
What are the official names of this protein?
Basic membrane protein B.
What is the protein family that this protein belongs to?
Belongs to the BMP lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PRH1_MOUSE
Sequence: MLVVLFTVALLALSSAQGPREENQNQIQIPNQRPPPSGFQPRPPVNGSQQGPPPPGGPQPRPPQGPPPPGGPQPRPPQGPPPPGGPQPRPPQGPPPPGGPQQRPPQGPPPPGGPQQRPPQGPPPPGGPQPRPPQGPPPPGGPQLRPPQGPPPPAGPQPRPPQGPPPPAGPQPRPPQGPPPTGPQPRPTQGPPPTGGPQQRPPQGPPPPGGPQPRPPQGPPPPGGPQPSPTQGPPPTGGPQQTPPLAGNTQGPPQGRPQGPR
What are the official names of this protein?
Proline-rich protein HaeIII subfamily 1, Proline-rich protein MP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: MPH1_SCHPO
Sequence: MSDDSFSSDEDWDELDTQVVDKIENEYHNNTIGLNGYSVDEYFDANDSNRYRLQHELDESAAQQWVYPINVSFRDYQFNIVQKALFENVLVALPTGLGKTFIAAVVMMNYLRWFPKSYIVFMAPTKPLVTQQMEACYKITGIPKSQTAELSGHVPVTTRNQYYQSRNVFFVTPQTILNDIKHGICDRTRISCLVIDEAHRSTGNYAYVEVVHLLSLSNKNFRILALSATPGNKLEAIQNVIDSLHISRIEIRTENSIDISQYVQKKEVDFFPVDLSAEITDIRDRFSSILEPMLQKLNKGNYYRIQNAKDITSFTVVQAKQAFLAMSGQNFPANQKWDILNTFDALATFAYPLNLLLNHGIRPFYQKLREVEEECFVGRSGYKKRIINHENYRPLMDDIEILLRDQSFVGHPKLEHLERIVTEYFEKEQTKDTRIMIFVEIRSSAEEILRFLGKFYPNVRPAIFIGQSAVRKAAGMSQKLQNETVKQFQKGEVNTLIATSIGEEGLDIGEVDMIICYDASASPIRMLQRMGRTGRKRKGYIYMLLTRGKEEAKWERAKDAYRTLQDNIVSGRGLSLSEKSYRILPEKFRPVCDKRVIEIPKENEEVVVAPKKVQLRTKIKKKFFMPENALNGFITASALGKPKRALAKSEESPFEICPVTYSIEQEKKLEKYKRVCLRGLDIHRNRRLSQLSVTGRIPHSLATKSIHSFLKHLNTIDSQKAQEWRREINNQFQVSNINSTDRDTKQPKMHDFRQPLHPNPMTTLKRKGQHNSFSYDKSTLFYDNNNNLEEDLPDVNISISSRNEEASKTKPFDDRQQRLQQLVEKRKRMKGMLI
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops (PubMed:18851838, PubMed:22844101, PubMed:22723423).  Plays a role in limiting crossover recombinantion during mitotic DNA double-strand break (DSB) repair (PubMed:18851838).  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (PubMed:18851838, PubMed:20347428).  FANCM-MHF also promotes non-crossover recombination in meiotic cells (PubMed:22723423).
What are the official names of this protein?
ATP-dependent DNA helicase fml1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: PRMA_SYNE7
Sequence: MPVSQSWWQVEVHCDPLLEDLLYWRLSEAGGRGFVCESKAQGLQVHSYFPAELWEETIRDRLLQEINADAADLGLPTPSLSWQTLDEEDWSESWKRHWQPQELGDRFLIQPAWLEPEPSDRLLLQLDPGTAFGTGAHPTTQLCLEGLETVPVADKVIADVGCGSGILAIGALLLGAKQVYAVDTDPLAVGATQANAALNDLEGDRFWTAIGSADQLQPLHAQGVRFDGFLCNILAHIIQALTPTLSELASPGSWAIFSGLLTSQADTVSVTLEEYGWVIRDRASQGDWCRLVADFRPER
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_SHIBS
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTYCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CUDP_METAN
Sequence: MHLSALLTLLPAVLAAPATIGRRAEPAPLFTPQAESIIADKYIVKFKDDIARIATDDTVSALTSKADFVYEHAFHGFAGSLTKEELKMLREHPGVDFIEKDAVMRISGITEQSGAPWGLGRISHRSKGSTTYRYDDSAGQGTCVYIIDTGIEASHPEFEGRATFLKSFISGQNTDGHGHGTHCAGTIGSKTYGVAKKAKLYGVKVLDNQGSGSYSGIISGMDYVAQDSKTRGCPNGAIASMSLGGGYSASVNQGAAALVNSGVFLAVAAGNDNRDAQNTSPASEPSACTVGASAENDSRSSFSNYGRVVDIFAPGSNVLSTWIVGRTNSISGTSMATPHIAGLAAYLSALQGKTTPAALCKKIQDTATKNVLTGVPSGTVNYLAYNGA
What is the function of this protein?
Capable of breaching the insect cuticle.
What are the official names of this protein?
Cuticle-degrading protease, Chymoelastase, PR1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_OENOB
Sequence: MASLQDIRRRIDSTKKTSQITSAMQMVSSSKLIQIQKHTSGYLDYANHVEAIVAHLAAAHLLEHQNGSSIPFITQRPVKTTAILVITSDRGLVGGYNNQVLKRTDQIMREQKLTKENAVIFALGGKGSDYYAKRGFTIAFENRDITDVPKFWEVSDLVKEVTKQYAARKFDALELVFNHFINRLKNDVVNQQILPIRSENFQRDEKGNLTADKYKGQSSIYEFEPAPESLLKIVLPQFAQSLLYGAILDAKTAEHAASASAMRAATDNAKDLISTLELKYNRARQAAITTEITEITGGMAALQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VE1_HPV53
Sequence: AFHYAQLADVDSNAQAFLKSNMQAKYVKDCGIMCRHYKRAQQQQMNMKQWIK
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TGM3_RAT
Sequence: MSALEVQNINWQMPMNRRAHHTDKFSSQDFIVRRGQPWEVILLCNRSLESGDNLNFIVSTGPQPSESARTKAVFSISGRNTSGWSAALKASNGNNLFIAIASPVSAPIGLYTLNVEVSSKGRVSSVKLGTFTVLFNPWQQGDDVFMSNHAERQEYVEEDSGIIYVGSTNRIGMVGWNFGQFEEDILSISLSILDRSLNFRRDPATDVARRNDPKYVCRVLSAMINANDDSGVLSGNWSGNYSGGVDPRTWNGSVEILKNWKKSGFRPVQFGQCWVFAGTLNTVLRCLGVPSRVITNFNSAHDTDRNLSVDVYYDAMGNPLEKGSDSVWNFHVWNEGWFVRTDLGPSYNGWQVLDATPQERSQGVFQCGPASVNAIKDGEVDQNFDMIFIFAEVNADRITWIYNNRDGSQKQNSVDTYSIGKYISTKAVGSNSRMDVTIKYKHPEGSKEERQVQQKAMNKLKPNASFGATSSRGPQGEEKEPSISGKFKVTGVLAVGKEVSLALILKNTTSDRKTVTTNMTAWTIVYNGTLVHEVWKDSATISLDPEEEIQYPVKIAYSQYDRYLKADNMIRITAVCKVPDEAEVVVERDVILDNPTLTLEVLDQAQLRKPVVVQMLFSNPLDEPVKNCVLMVEGSGLLRGSLKIDVPALRPKEKSRVRFEIFPTRIGIKQLLADFSCNKFPAIKAMLVIEVSE
What is the function of this protein?
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins.  Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes.  Catalyzes small proline-rich proteins and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold.  In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath (By similarity).
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGE, TGase E, Transglutaminase-3, TGase-3.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_HUMAN
Sequence: MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCGWTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, M2 antigen complex 70 kDa subunit, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: GIPR_RAT
Sequence: MPLRLLLLLLWLWGLSLQRAETDSEGQTTGELYQRWERYGWECQNTLEATEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWYRQVAAGFVFRQCGSDGQWGSWRDHTQCENPEKNGAFQDQKLILERLQVVYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAGAILTRDQLLPPLGPYTGNQTPTLWNQALAACRTAQILTQYCVGANYTWLLVEGVYLHHLLVVVRRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLMPLLGVHEVVFAPVTEEQAEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRLRLSLQEQCPRPHLGQAPRAVPLSSAPQEAAIRNALPSGMLHVPGDEVLESYC
What is the function of this protein?
This is a receptor for GIP.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB_SHEPA
Sequence: MNVVQGNIESKNAKVAIVVSRFNSFVVDSLLDGAVDTLKRFGQVADENITVVKVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDIPVSFGVLTTDTIEQAIERSGTKAGNKGGEAALGLLEMVNVLQALEEQL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ROT1_NEOFI
Sequence: MIVGYLLLNFLVAVVRASSVAELVGTWTTKSRTVVTGPDFYDPIDDKLLEPSLTGISYSFTADGYYEQAYYRAVSNPTTPSCPKGIMLWQHGKYAVMPDGSIQLTPIAVDGRQLVSDPCSKEVAMYTRYNQTEAFSSFTVSIDSYHHVKRLDLKAFDETPMPPMYLIFKPPQMLPTTTLNPVSSETGKSKRHIARDIGSPVGVDTLMRSDHIGDPGRWLWFGIFMTAMGGIALIYS
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein rot1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ATPL_VEREI
Sequence: MEIILGFVALACGLIVGLGAIGASIGIGLMGGKFLESSARQPELINELQTKMFILAGLIDAAFLIGVAIALMFAFANPFVSTLLANMPK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_CAMLR
Sequence: MQDLISQISSASTLAELENIKVSVLGKKGILTLEFAKLKDLQGEEKKEFANGLNKTRDEFNEAYQVKLKELEEKALNEKMKQDVQDFSFFDETSNAGALHPIMQTMDKIIEYFTALNFSIEKGPLIEDDFHNFEALNLPQNHPARDMQDTFYFEDKTLLRSQTSPVQIRTMLSQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGDKINFANLKDMLENFLKYMFGDVKVRFRPSFFPFTEPSAEVDISCVFCKGCGCRVCKHTGWLEVLGCGVVDPNVYKFVGYKNVSGYAFGLGVERFAMLLHKIPDLRSMFEGDLRLLEQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ECOL6
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVAEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: PFL2_SCHPO
Sequence: MKFFTASTLFLLAAQSLNSGVSASLSDPANTPTILADDIVHGYTPATYLSSVPTLLKRATTSYNYNTSSASSSSLTSSSAASSSLTSSSSLASSSTNSTTSASPTSSSLTSSSATSSSLASSSTTSSSLASSSITSSSLASSSITSSSLASSSTTSSSLASSSTNSTTSATPTSSATSSSLSSTAASNSATSSSLASSSLNSTTSATATSSSLSSTAASNSATSSSLASSSLNSTTSATATSSSISSTVSSSTPLTSSNSTTAATSASATSSSAQYNTSSLLPSSTPSSTPLSSANSTTATSASSTPLTSVNSTTTTSASSTPLSSVSSANSTTATSTSSTPLSSVNSTTATSASSTPLTSVNSTTATSASSTPLTSVNSTSATSASSTPLTSANSTTSTSVSSTAPSYNTSSVLPTSSVSSTPLSSANSTTATSASSTPLSSVNSTTATSASSTPLSSVNSTTATSASSTPLTSVNSTTATSASSTPLTSVNSTSATSASSTPLTSANSTTSTSVSSTAPSYNTSSVLPTSSVSSTPLSSANSTTATSASSTPLTSVNSTTATSASSTPFGNSTITSSASGSTGEFTNTNSGNGDVSGSVTTPTSTPLSNSTVAPTSTFTSSGFNTTSGLPTSSASTPLSNSTVAPTSTFTSSGFNTTSGLPTSSASTPSSNSSIVPTSTFTSSGFNTTSGLPTSSASTPLSNSTVAPTSTFTSSGFNTTSGLPTSSVSTPLSNSSAYPSSGSSTFSRLSSTLTSSIIPTETFGSTSGSATGTRPTGSSSQGSVVPTTSTGSSVTSTGTGTTTGVTEVTETSTFETTEIITSTIEPTTASGTGGGNPTAAPTNEPTVTTGTETTEGTATYTEPTTFTSTFSFTTTIIGGTTTIIPVNPGNPSSSVSAPPTTSFTPGPGGSGYPSYSNTTQGMNTTSIWNSSNSTIVSNVTATITGNVTITTGDLTTIDPTTFTSTYLSSGFQTVSNTTATSGSDDDVKTASTSSSTSYTSSSSSSSSTTSAASSKASVSMGLNGLMIAAVILLVA
What is the function of this protein?
May be involved in agglutination during conjugation or other aspects of colony formation (By similarity).  Induces flocculation when overexpressed (PubMed:23236291).
What are the official names of this protein?
Putative GPI-anchored protein pfl2, Pombe flocculin 2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: NDUF4_BOVIN
Sequence: MGAAVARAVRNFNLENRAEREISRMKPSPAPRHPSTKNLLLEQMSSHPEIKGEIDRKDDKLLSLLKDVYVDSQDPVSSLQVKDATARQKPKEFRLPKDHQFDMMDVKNIPKGKISIVEALTLLNNHKLYPDTWTAKKIAEEYHLEQQDVNSLLKYFVTFEVKIFPPEGKKAIESK
What is the function of this protein?
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (By similarity).  May be involved in cell proliferation and survival of hormone-dependent tumor cells.  May be a regulator of breast tumor cell invasion (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4, Hormone-regulated proliferation-associated protein of 20 kDa.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF4 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Lipid-anchor.
Protein: PTH_LISMO
Sequence: MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.