PharMolix/UniProtQA huggingface dataset:
Protein: ARRS_BOVIN
Sequence: MKANKPAPNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHPQPEDPDTAKESFQDENFVFEEFARQNLKDAGEYKEEKTDQEAAMDE
What is the function of this protein?
Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed:8003967, PubMed:25205354).  May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (By similarity).
What are the official names of this protein?
S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
[Isoform A]: Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. Note=Highly expressed in photoreceptor outer segments in light-exposed retina (PubMed:7515057). Evenly distributed throughout rod photoreceptor cells in dark-adapted retina (PubMed:7515057). Predominantly dectected at the proximal region of photoreceptor outer segments, near disk membranes (By similarity). SUBCELLULAR LOCATION: [Isoform B]: Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein.
Protein: YCF78_OLTVI
Sequence: MFFVSAVKDYLEVLSNITDTLTGTLSFDTILKSTLLYLATSTKVFVSYIISFEWFRNISYLPIIAPDLSKAILRENYVLDTPLSNLFTFFDVPSYTSNKFVLGLLNSFFLAIPISVAHLIAFRRFIIQGLPAGLTAGLGIISGQVCFIGAVLFGVRSLVIPWFATEPLSYLIGIFLILTIIYDMAHESRIRPINLSETPLLLKIFGLSFLLTWTEQSSVFQYLANVTLGNQATLLETTTVKTDGQFLLTHISYLLGLTAGNILFTLLFGFLLLQLINQVVKFSNLPYSLCVRNLNFGILTFTLALSITSIPYYGFDYLLTAPLGFVSQDQSLEKVSLRTNLPDAIGYLGQLSESKYLDTEVTPFDRGTYLTDFATPKTYESLNYQGEYFWNSRLDRSASVTQKYRALEFNPKKDSESEIPEQVGALSPDSQANSVSPGQELSENELGLGTTKTNKQVLLNKLDQNFSRNSNPSYANLLSEVLDYSFNESFFTTSASNAPQEVALQKIEFNIKQKYYSNPLYKALLNFDIDRFISHQPVAQRLNANQEKQLFENRLILSTYYDTLRDYRLLPYSSEFQTYFNGPKSYANRVYNQQFKGTLNVVRRLFAIDIEGDSAGRSTSNSVLKFDQPLFNNFKDSSLSVYHEELNPEAVRPTKKSPFLENTSPTPFYAGWDNIQRKFIVTNRLLAREAAGNEINRASRNISSATSALTAKDYTSLGDTVKLKFTSWPDSSSKGGNSKGVNQLSLPFISVPQEKFTQVVSSLGLEDDDFGSASSTLKLPPNIKKMFEVCQISIPEVFPPKRGGFIWP
What are the official names of this protein?
Uncharacterized membrane protein ycf78, RF1, ycf1.
What is the protein family that this protein belongs to?
Belongs to the ycf78 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: DAPA1_ARATH
Sequence: MSALKNYGLISIDSALHFPRSNQLQSYKRRNAKWVSPIAAVVPNFHLPMRSLEDKNRTNTDDIRSLRVITAIKTPYLPDGRFDLQAYDDLVNTQIENGAEGVIVGGTTGEGQLMSWDEHIMLIGHTVNCFGGRIKVIGNTGSNSTREAIHATEQGFAMGMHGALHINPYYGKTSIEGMNAHFQTVLHMGPTIIYNVPGRTCQDIPPQVIFKLSQNPNMAGVKECVGNNRVEEYTEKGIVVWSGNDDQCHDSRWDHGATGVISVTSNLVPGLMRKLMFEGRNSALNAKLLPLMDWLFQEPNPIGVNTALAQLGVARPVFRLPYVPLPLSKRIEFVKLVKEIGREHFVGDRDVQVLDDDDFILIGRY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, HTPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS14Z_CAMHC
Sequence: MAKKSMIAKANRPAKFSSRAYTRCKICGRPHSVYRDFGICRVCLRKLANEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: TORT_ECOLI
Sequence: MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRAWKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWGAEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQWAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQEMLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASDQMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFYQHTSAAKK
What is the function of this protein?
Upon binding a putative inducer it probably interacts with TorS and allows it to play a role in the induction of the torCAD operon for trimethylamine N-oxide reductase.
What are the official names of this protein?
Periplasmic protein TorT.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MYOK_DICDI
Sequence: MFRLFSSGVDDLVLVSNPSNGEVTSQIGARFDRELIYTNIGEVLIAVNPYKALPITGPEFIKLYQNASGSDASPHIYALAERAYRRMVDENESQCVIISGESGAGKTVSAKLILQYVTSVSPNNSSGGGIGGSGGGNGGIPQYDGGSDDRPSPPMGRGMGMPGMVGRGGLPTRGGGPPSRGGGPPPTRGRGGPPPPIPQNRGAPPPVSNGGAPPPVARGPVAPPPTRGAPPTRGGGPANRGGRGGGPPPVSTSRGGGGYGGSSKTVDVEHIKKVILDSNPLMEAIGNAKTVRNDNSSRFGKYLEIQFDDNNAPVGGLISTFLLEKTRVTFQQKNERNFHIFYQMLGGLDQTTKSEWGLTQATDFYYLAQSKCTTVEDVDDGKDFHEVKAAMETVGISRDEQTEIFRILAAILHVGNIRFQGEAPASVIDETPLQWAASLLGCDPTFLCQSLNHRQIQSGSARHTQYQVPQNPDQSAGLRDALAKTLYERIFDFIVARVNKAMSFSGNCKVIGVLDIYGFEVFERNSFEQFCINYVNERLQQIFIDLTVRGEQREYHEEGMKWKDISFFDNKIVVDLIDGNKPPGIMRVLDDVCKTVHAVDSAAADIKFMEKLIHSIQSHPHLVISNTGSSADEFTIKHYAGEVSYSIEEFCFKNNDNLYASIVGCLQNSTYQFIVSLFPENIQDNKQAPTTSSFKIRQSSSYLVTRLSACTPHYIRCIKPNDKKQPMNFVSSRVEHQVKYLGILENIKVKRSGYAYRQLKDIFLNRFGKIMDVQPRNVQEFVEYITRTHKDINADEFEEGKTKIFVKNPETIFVMEDLLMQKIDPIGYKNRVQAYKENEKLAQMKQGKHSMKQKCLIQ
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Involved in phagocytosis and motility, and in the maintenance and dynamics of cell cortex.
What are the official names of this protein?
Myosin-K heavy chain.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: GYS_CAEEL
Sequence: MPDHARMPRNLSSNKIAKTIAGEDLDEEEVLEMDAGQSAREEGRFVFECAWEVANKVGGIYTVLRSKAQISTEELGDQYCMFGPMKDGKWRLEVDPIEPENRTIRAAMKRFQADGFRCMYGRWLIEGYPKVILFDLGSGAVKMNEWKHELFEQCKIGIPHEDIESNDAVILGFMVALFLKHFRESVTSYTPLVVAHFHEWQAGVGLLMTRLWKLDIATVYTTHATLLGRHLCAGGADLYNNLDSFDLDAEAGKRKIYHQYCLERAACQTAHIFTTVSEITGLEAEHFLCRKPDVLTPNGLNVVKFAALHEFQNLHAQNKEKINQFIRGHFHGHLDFDLDKTLYFFTAGRYEFSNKGGDMFIESLARLNHYLKTTSDPRHMGVTVVAFLIYPAPANSFNVESLKGQAVTKQLKEAVDRIKEKVGQRIFDICLQGHLPEPEELMSPADNILLKRCIMSLHNSSLPPICTHNMIRADDPVLESLRRTSLFNKPEDRVKVVFHPEFLSSVSPLIGLDYEDFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVSTNLSGFGCFMQEHVEDHEQKGIYVIDRRHKAAEESVQELAQVMYDFCGQSRRQRIILRNSNEGLSALLDWQNLGVFYRDCRRLALERLHPDVDKIMRDNEGKVPSAATSRRPSIHSSDGEDDE
What is the function of this protein?
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
What are the official names of this protein?
Glycogen [starch] synthase, GS.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 3 family.
Protein: WHIB4_MYCTO
Sequence: MSGTRPAARRTNLTAAQNVVRSVDAEERIAWVSKALCRTTDPDELFVRGAAQRKAAVICRHCPVMQECAADALDNKVEFGVWGGMTERQRRALLKQHPEVVSWSDYLEKRKRRTGTAG
What is the function of this protein?
Acts as a transcriptional regulator.  Probably redox-responsive.  The apo- but not holo-form probably binds DNA (By similarity).
What are the official names of this protein?
Transcriptional regulator WhiB4.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CLOBJ
Sequence: MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKKHSNVEVQCFSGLLIDFMKEKKSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTNAKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHKKECI
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX4_RAT
Sequence: MGDEDWEAEILKPHVSSYVPVFEKDKYSSGANGDTFNRTSASSSEMEDGPSGRDHFMRSGFSSGRNLGNRDIGESSKRETTSTTGGFGRGKGFGNRGFLNNKFEEGDSSGFWKESTNDCEDTQTRSRGFSKRGGYPDGNDSEASGPFRRGGRDSEYDQDQGSQRGGGLFGSRKPAASDSGSGDTFQSRSGNARGAYKGLNEEVVTGSGKNSWKSEAEGGESSDIQGPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGEFLKSNYLFVAVGQVGGACRDVQQSILQVGPVFKKRKLVEILRNIGDERPMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFNLPSTIDEYVHRIGRTGRCGNTGRAISFFDTESDNHLAQPLVKVLSDAQQDVPAWLEEIAFSSYAPPSFSNSTRGAVFASFDTRKNFQGKNTLNTAGISSAQAPNPVDDESWD
What is the function of this protein?
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle.  Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog, rVLG.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: PYRD_SODGM
Sequence: MLYPLIKQALFQLDPERAHELTFQQLKRITGTPLEWLVRQSVPTKTVNCMGIAFKNPLGLAAGLDKDGDCIDALGAMGFGFIEVGTVTPRAQPGNEKPRLFRLVKAGGLINRMGFNNHGVDNLVENVRKSHFGGVLGINIGKNKDTPVEQGKDDYLTCMEKVYPYAGYIAVNISSPNTPGLRTLQFGEALDDLLLAIKNKQVALQAYHHKYVPVAVKIAPDMTEAELIQVADSLVRHNIDGVIATNTTTGRVLVQGMNHCGQTGGLSGRPLQLRSTEVIRQLSAELQGKLPIIGGGGIDSLIAAREKMAAGASLIQIYSGFIFHGPRLIKDIVSDI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS17E_METHJ
Sequence: MGIKPTYIKKIGIELLEFHEEKFTNDFDENKKAVASATNVPSKRVRNRVAGYITRKINTGKFKK
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: CLPP2_TROWT
Sequence: MSETKQTVFDRLLQERIVWLGEAIDDKLANEICAKILLLNADDPKEDIFLYINSPGGSITAGMAIYDTMQFVSNDIVTVGIGMAASMGQVLLTSGTQNKRYIMPNARVLLHQPLAGFGGTASDIQTQAKLILDMKYRLSQITASRTGKTVEQIMEDGDRDHWFTAEEALEYGFVDHIRTE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NITR3_UNKP
Sequence: MKVVKAAAVQISPVLYSREATVEKVVKKIHELGQLGVQFATFPETVVPYYPYFSAVQTGIELLSGTEHLRLLDQAVTVPSPATDAIGEAARKAGMVVSIGVNERDGGTLYNTQLLFDADGTLIQRRRKITPTHFERMIWGQGDGSGLRAVDSKVGRIGQLACFEHNNPLARYALIADGEQIHSAMYPGSAFGEGFAQRMEINIRQHALESGAFVVNATAWLDADQQAQIIKDTGCGIGPISGGCFTTIVAPDGMLMAEPLRSGEGEVIVDLDFTLIDRRKMLMDSAGHYNRPELLSLMIDRTATAHVHERAAHPVSGAEQGPEDLRTPAA
What is the function of this protein?
Nitrilases catalyze the mild hydrolytic conversion of organonitriles directly to the corresponding carboxylic acids.
What are the official names of this protein?
Nitrilase 3, Nitrilase III.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: EFP_LEPBL
Sequence: MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEKLESVELEKRNMTICYTEGNDIIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGEINVPIFVKQGDVIKIDLRDLTYVERVSR
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BURA4
Sequence: MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASQSDHATDILNALVALGYSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FRUR_BACSU
Sequence: MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLSDIRLEPDMLEKSSKNLHDKLKIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVVTNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAMDQYRFDKSFLGTNGVHTEAGFTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNYQEKTVVKVVKP
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator FruR.
Protein: E2F7_BOVIN
Sequence: MEVNCLTLKDLISRPPRLDFAIEDGENAQKENIFVDLSRMAPKTPIKNEPIDLSKQKIFTPERNPITPVKLVDRQQVEPWTPTANLKILISAASPDIRDREKKKELFRPIENKDDVFTDSLQLDAVDDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYSWHGRHSLPKTLRNLQRLGEKQKYEEQMAHLQQKELNPIDHKSGERRRDGCPDSQDPQLLDFPEPDCPSSSANSRKDKSLKIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDIPDHSKFKTKVRRLYDIANVLTSLMLIKKVHVTEDRGRKPAFKWIGPVDFSSTDDDLVDVSTPVLPELKKEIYGHVQFCAKQKLARHSSFNSEQASERTQRKVNSEPSSPYRQKQGLGVYSLEIGSLAAVSRQKMEDNSETVAFASQNMMPLPSSLDPAAPLPSPSVDSEYRVSPLCHQALSAAQTDLKALPAQNGLNGQGGVSLASMALDVEHQPQPLAAAQPLLYVPPAPLFMLCGGLQEGLSPGSGSGSGSVGGGSEVTAAEQPPMPSGQKRLSKERRLQEEEEEPATKRQCRDHEDGPLSLVMPKKPSDSADIASPKTSENRASAPHEDTHMNGQLSAAKAVSGKATTNGFVSSEWGNPCSNTEIEKPSEENESTKGPSPLQYLYVQPPAGLNGLSVLLPSSQSPHAVGLPVGPLPSLSIQYMVLPSPALSGFPVLCSPTMPGPVSSAPSPLPNVGPVNFGLPGLGSTAHLLIGPAAMVNPKSSTLPSTDPQLQGPCSLHLSPVMSRSHGSVQPGSPAYGSLPAATVKLQQSPVPVTPKSIRCTHQETFFKTPGSLGDPVLRRKERNQSRSSSSAQRRLEISSGGTD
What is the function of this protein?
Atypical E2F transcription factor that participates in various processes such as angiogenesis, polyploidization of specialized cells and DNA damage response.  Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'.  Directly represses transcription of classical E2F transcription factors such as E2F1.  Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC-3' and mediating repression of G1/S-regulated genes.  Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3).  Required for placental development by promoting polyploidization of trophoblast giant cells.  Also involved in DNA damage response: up-regulated by p53/TP53 following genotoxic stress and acts as a downstream effector of p53/TP53-dependent repression by mediating repression of indirect p53/TP53 target genes involved in DNA replication.  Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene.  Acts as a negative regulator of keratinocyte differentiation (By similarity).
What are the official names of this protein?
Transcription factor E2F7, E2F-7.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BL1S2_CAEEL
Sequence: MAEINERASTSSPPVPSTPAPVPHIRQLADNMTDKVGQFFQHQLEGSIEEYKLLETMNNTTAQRYVDMKVVAEKVAGKLDNLNQKYENLRPYLSQIDAMDESTRRLEEATAVLENYVTQLESKLTNIQQQSQ
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in gut granule biogenesis.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 2, BLOC-1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S2 family.
Protein: BTCB_COLOR
Sequence: MASSSIASFAPFESYSPPLNTSETSLISVQLTQDGLDYHGALAFLCGALLFGFVYSVFYNLYLSPIARVPGPLIAQVSPLWLMRAVCRKQLNCDIKKLHEKYGKKPERSPVVRLSPTEVSFATVEAQNAIHRPGASAKQGLFFTKEGTLEAMMGEIIWPATNLLTATVPEEHQRLKKALQPAFTEKALQLQEPIQQQHTDRLIRSVQEASRQNRVVDLTPHMSQAIWDIISDLSFGEPLLKDQLAKFERLKTTFCMVSPLLEALQVLLAVPGAQTLAKACVGLVPLLFWLPTNVLPSAQLRKRFERQDSNEDFLTAIMRCREMGIQMTDMELQSNASLLVMVGYDTTATSLSATMNLLLRHPLCLQALQDELHSHFSSTSDMTSKPLSQLPILNGCIQESLRLFPPANGKGTNRTSPGTMIDGVYIPRGVNVSADMYTIQRSPTYWSRPNEFCPDRWFDNGPGTEFAQDVRSSHNPFLLGPRMCIGRAVALQSMRMLIAKLVYTFDLEAVEDYSWDLHVANSYLWTGYRCNARV
What is the function of this protein?
Cytochrome P4590 monooxygenase part of the gene cluster that mediates the biosynthesis of betaestacins (Ref. 3).  The bifunctional terpene synthase btcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene betaestacin I (Ref. 3).  The C-terminal prenyltransferase (PT) domain of btcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into betaestacin I (Ref. 3).  The cytochrome P450 monooxygenase btcB oxidizes the C25 methyl group of betaestacin I to yield the carboxylic acid betaestacin IV via the alcohol betaestacin III (Ref. 3).  The cytochrome P450 monooxygenase btcC further catalyzes the multistep oxidation of betaestacin IV to produce several compounds, including betaestacins Va, Vb, Vc and VI (Ref. 3).
What are the official names of this protein?
Cytochrome P450 monooxygenase btcB, Betaestacins biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IOVO_VULGR
Sequence: IATVDCSDYPKPVCSLEDMPLCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: SUT11_ARATH
Sequence: MSGTINPPDGGGSGARNPPVVRQRVLAPPKAGLLKDIKSVVEETFFHDAPLRDFKGQTPAKKALLGIQAVFPIIGWAREYTLRKFRGDLIAGLTIASLCIPQDIGYAKLANVDPKYGLYSSFVPPLIYAGMGSSRDIAIGPVAVVSLLVGTLCQAVIDPKKNPEDYLRLVFTATFFAGIFQAGLGFLRLGFLIDFLSHAAVVGFMGGAAITIALQQLKGFLGIKTFTKKTDIVSVMHSVFKNAEHGWNWQTIVIGASFLTFLLVTKFIGKRNRKLFWVPAIAPLISVIISTFFVFIFRADKQGVQIVKHIDQGINPISVHKIFFSGKYFTEGIRIGGIAGMVALTEAVAIARTFAAMKDYQIDGNKEMIALGTMNVVGSMTSCYIATGSFSRSAVNFMAGVETAVSNIVMAIVVALTLEFITPLFKYTPNAILAAIIISAVLGLIDIDAAILIWRIDKLDFLACMGAFLGVIFISVEIGLLIAVVISFAKILLQVTRPRTTVLGKLPNSNVYRNTLQYPDAAQIPGILIIRVDSAIYFSNSNYVRERASRWVREEQENAKEYGMPAIRFVIIEMSPVTDIDTSGIHSIEELLKSLEKQEIQLILANPGPVVIEKLYASKFVEEIGEKNIFLTVGDAVAVCSTEVAEQQT
What is the function of this protein?
High-affinity H(+)/sulfate cotransporter that mediates the uptake of the environmental sulfate by plant roots under low-sulfur conditions.  Plays a central role in the regulation of sulfate assimilation.
What are the official names of this protein?
Sulfate transporter 1.1, AST101, High-affinity sulfate transporter 1, Hst1At.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PH3_PERAM
Sequence: AFLTLTPGSHVDSYVEA
What are the official names of this protein?
Peptide hormone 3, Pea-VEAacid 1.
Protein: RSMH_VEREI
Sequence: MSSAPCHTTVLREPAVDALLARAGPAPAGTWVDATFGRGGHTRLILCRLGPQGRLVAFDKDPEAIAEAMRITDARFSIRHQGFGQLGQLPAGSLAGVLMDLGVSSPQIDSPERGFSFRFDGPLDMRMDTTRGLSAADWLATADAGQIAQVLRDYGEERFAGLIAKAIVARRQARGPLARTAELADLVAGAVKTREPGQNPATRTFQALRIFINAELEELQQALAASLLVLQPGGRLVVLSFHSLEDRIVKQFIARHSRQPFDRRVPFAAPQAMQLLALARVRPDAAEVAANPRARSAIMRVAERTQAHGAERSDMRRAERPDARRAEHGEVLPP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_STRPF
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.