PharMolix/UniProtQA huggingface dataset:
Protein: YNV8_SCHPO
Sequence: MSIMRSIMSNRLVRWSREYPELFITWCVMTYTFGVAGYMLGQRGLLVQHEDQVRIPSKNAHPWEDTKSSSGKSDESLDYSYKYYPRGDRSKEPRKAPSAIQYSTFPVKGVSEEVLERFSK
What are the official names of this protein?
Uncharacterized protein C3H7.08c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDC_RHIME
Sequence: MENNRNYFVAIALSVLILIAWQFFYVSPKMEKDRIAAEQAQQAQQTQQQPGAQPAAPGQALPGGAIPSAGESRDQAIGKSARVAIDTPALSGSINLTGARFDDLKLKGYRETVDPKSPVITLFSPAETADGYFTEIGYIGSDATGSVPGPQTTWTLSGGDKLTPSTPVTLSYTNDKGITFARTISVDDRYMFQVVDSIKNETAAPVSLSSYGRVTRFNKPTTPSIYVLHEGFVGVAGEHGLQEVGYSKVEDDEPVEPGKSTGGWLGITDKYWAATIVPPQATPFDIRFSHFADGRPRYQSDYKSDAVTVAPGQSVELKNLVFAGAKEVPVVDNYEVAYSIPNFDKLIDWGWFYFITKPMFKMMDFFFRLFGNFGIAILITTIVVKLIFFPLANKQYASMANMKKVQPKMEELKKKFGDDRMGLQQAMMQLYKEEKINPLAGCWPILIQIPVFFALYKVIYVTIEMRHAPFFGWIQDLSAPDPTTIINLFGLLPFEGPAFLHLGIWPIIMGVTMFLQMRMNPTPPDPTQAMLFTWMPVVFTFMLASFPAGLVIYWAWNNTLSILQQGIIMKRQGVKVELFDNLKSLFSKKPKPAE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CMBB_DICDI
Sequence: MTSNHLPHHNLTDEDQQEYNKIFKEFIFNIPHNMNPFSPQLDEKKNSHIVEYHWRSPSNTIPSTCNTLYVCFNSPIPVNVIPNNVIILCFLCENKTGFTKGPDFNHPIHPGTIPMSVRYIYFINATYNKPLIAHALPPSAEYLFLSDCYNQAFRAGDLPPNLNILETGDEYNQPFDPLVIPKSLRSLFLGKGYNQPLEFGGLTSLTCLVYDEGSISELPIISLPPNLEFLLLSDAFNHPIEAGMLPPKLKTLTFGDGFNQPLAVGTLPPSLENINFGKVFDQPFLPNVLPHHLKSISFHQFSYFSQTFENIPSHVQTVEFGYTYNKPITSLPSHLKYIKFSEKYNHPIDGVLPQSLTHCYLGKSFKRPLVPGIFPPGLKVLILNGYPKKIPPGTVPANCNFQKNPKQGACSVM
What are the official names of this protein?
Calmodulin-binding protein CmbB, CaM-BP46.
Protein: RRN11_SCHPO
Sequence: MFSPCTVKEKRSTLRSVAPNPESSVIPPIPLPSRRYKTRHIDALCSLMHLCLLRKDYPRASRAFSLLLRSKSVDISKLWNIGLEILNKVNPEASSEYMERLIARYPARPSINNSYPNRNAEHFFPAYIMLLIQRQEYNKAMKLLDEYLLLPPYNQNPALHEYSGMLCFELAKEEASESERTKWIEKAKYNFSNAGIDVEL
What is the function of this protein?
Subunit of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I.  Binding to the DNA template is dependent on the initial binding of other factors.
What are the official names of this protein?
RNA polymerase I-specific transcription initiation factor rrn11.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH4_XANC8
Sequence: MSTTLPDIAVTEPSALHAPLRWVGMQDIAIPVRLDEAEPSGTVAARAQVQVDLPRPELKGIHMSRLYRLLDRHLEQPLSPAMLSQLLQAMIDSHADCGSRAARVSLAFEVMLRMPALRSEGLAGWRAYPVRIDAQSRAGRSEMRLQIDVLYASTCPCSAALSRQLLSKAFAQQHAGQTALRVEDVAQWLQRNGSYATPHSQRSVAQVRVDLVARVQSFDIRALVLLCESALATPVQAAVRRIDEQAFARLNGANLMYVEDAARRLRKELAERYASFHVAVRHFESLHAHDAVAETGSDADVFHMIAESHGQ
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: U3_TIBVC
Sequence: MSKVGPNPFLQFYLNAKNDFINWVSIIWGKIRMIALVITLIVAFIFLIKLIKSCIYLVSLCKGCLTKTLTFKNKIIKWNIWKKIKRRTPRESRLKDCPIYLNNPNFQLN
What are the official names of this protein?
Protein U3.
What is the protein family that this protein belongs to?
Belongs to the tibrovirus protein U3 family.
Protein: GUAA_PROMH
Sequence: MTANIHNHRILILDFGSQYTQLIARRIREIGVYCELWAWDVTEEQIREFNPNGIILSGGPESTTEDNSPRAPEYVFNAGVPVLGICYGMQTMSMQLGGDVEVSGEREFGYSQVEIRETCELFRDIQDSVSEDGKPLLDVWMSHGDKVTAIPADFVTIASTETCPFAIMANEEKRFYGVQFHPEVTHTHQGLAILKRFVLDICGCDALWTSAAIIEDTVARLKQQIGDDHVILALSGGVDSSVTALLLNRAIGKRLTCVFVDNGLLRLNEAEQVMAMFKGKFDLNIIHVEAEDRFLTALKGENDPEKKRKIIGHTFIEIFDEEAVKLPQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPEDMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEIKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MAD25_ORYSJ
Sequence: MGRGKIAIKRIDNTMNRQVTFSKRRGGLMKKARELAILCDADVGLIVFSCTGRLYDFSSSSMKSIIERYQEAGEEHCRLLNPMSEAKFWQREVTTLRQQVQNLHHNNRQLLGEEISNFTVRDLQLLQNQVEMSLHSIRNKKDQLLAEEILKLNEKGSLVQKENSELRKKFNIAHQRNIELHKKLNSGESTSSEQVTRSSKDPGESSTPRDSRVCIDLELSQKEVEDE
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
MADS-box transcription factor 25, OsMADS25.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_CHLAB
Sequence: MRVGIIGCSGRMGTLLSSLLRSSNRFTLGPGFSRQSPYSLDSVIESNDVLVDFSSSSFSEELLIALLSNPKPLIFATTKPEPSYSVDEKLQRLAAYVPVVVCPNTSLGAYVQKRLVGLLARVFDDRYDIRISEVHHREKKDPVSGTAKELASILCHTKQEAWQQEYSIGSRCHSVKNIELHVSRVGNISGEHEVAFISDKEHISIHHKVFSRAVFAEGALRILDWLIDESPPPGCYGPEVGLKVSM
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIDEB_HUMAN
Sequence: MEYLSALNPSDLLRSVSNISSEFGRRVWTSAPPPQRPFRVCDHKRTIRKGLTAATRQELLAKALETLLLNGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLQSGQSWSPTRSGVLSYGLGRERPKHSKDIARFTFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGLGPKKVLRELLRWTSTLLQGLGHMLLGISSTLRHAVEGAEQWQQKGRLHSY
What is the function of this protein?
(Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
What are the official names of this protein?
Lipid transferase CIDEB, Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
Protein: RECF_STREM
Sequence: MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIYFLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQAKLSDYIGAMMVVLFAPEDLQLVKGSPSLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQRNAYLKSVHQLDSDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKLSISYQASVSFEHQQEIYQQFMDQLKTTHQRDFLRKNTGVGPHRDDLIFYINGMNANFASQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNIRQTKLLEAVKKENVQTFITTTSLKHLSQLPKDISLFKVNKGTIALDSVMID
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDX_MOUSE
Sequence: MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMSSKSCESGAAGTVSGTSLAAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPVSSSSKQGTTKHTNTQITEAHKIPIQKAANKNDTELQLHIPVQRQVAHCKNASVLLGEKTIILSRQTSVLNAGNSVYNHTKKSYGSSPVQASEMTVPQKPSVCQRPCKIEPVGIQRSYKPEHAGLASHNLCGQKPTIRDPCCRTQNLEIREVFSLAVSDYPQRILGGNSTQKPASAEGTCLSIAMETGDAEDEYAREEELASMGAQITSYSRFYESGNSLRAENQSTNLPGPGRNLPNSQMVNIRDLSDNVLYQTRDYHLTPRTSLHTASSTMYSNTNPSRSNFSPHFVSSNQLRLSQNQNNYQISGNLSVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVAIELNVDCEIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEASSQEESNELIPNETRAHKDEEHQAVSADNVKIEIIDDEESDMISNSEVEQENSLLDYKNEEVRFIENELEIQKQKYFKLQSFVRNLILAMKADDKDQQQALLSDLPPELEEMDCSHASPDPDDTSLSVSSLSEKNASDSL
What are the official names of this protein?
Highly divergent homeobox.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_CAMJJ
Sequence: MAKKSMIAKAARKPKFKVRAYTRCQICGRPHSVYRDFGICRVCLRKMGNEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NIFH_TOLAT
Sequence: MALRQCAIYGKGGIGKSTTTQNLVSALAEMGKKVMIIGCDPKADSTRLILHAKAQNTIMEMAAEVGSVEDLELEDVLQIGYGGVRCAESGGPEPGVGCAGRGVITAINFLEEEGAYEEDLDFVFYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNISKGIVKYAKSGSVRLAGLICNSRQTDREDELIIALADKLGTQMIHFVPRDNIVQRAEIRRMTVIEYDPTCKQANEYRTLANKVVNNKLFVVPTPVTMDELEELLMEFGIMDVEDETIIGKTAAEEAAATA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: 3MGH_CLOPE
Sequence: MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTNRTETLYADPGTVYVYIIYGMYHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSYEELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIYVEDDSLIKKDFSIVEAKRIGIDYAEEARDFLWRFYIKDNKFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RL20_TRIV2
Sequence: MTRVKRGNVARKRRNKILKLAKGFRGSHSTLFRTANQQVMKALRSAYRDRKKKKRDFRRLWITRINAAARQHGLSYSQLIGNLKKADIQLNRKMLAQLAVLDPASFGKVAELAIQAKG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: COPG1_BOVIN
Sequence: MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDSYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHGLKSPFAYCMMIRVASRQLEDEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDANRSIATLAITTLLKTGSEGSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFSMLREEGGFEYKRAIVDCIISIIEENAESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPRTSNPSKYIRFIYNRVVLEHAEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLAVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPLAEQRTESTPVTAAKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFTDHMVFQFDCTNTLNDQTLENVTVQMEPSEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPTTGEADDEGYEDEYVLEDLEVTIADHIQKVMKLNFEAAWDEVGDEFQKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIVLASVG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.  Required for limiting lipid storage in lipid droplets.  Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-1, Gamma-1-coat protein, Gamma-1-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis-Golgi apparatus.
Protein: LPXA_ECOK1
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_STRA1
Sequence: MDIKLKDFEGPLDLLLHLVSKYEVDIYDVPIVEVIEQYLAYIATLQAMRLEVAGEYMLMASQLMLIKSRNLLPKVVESNPIEDDPEMELLSQLEEYRRFKVLSEELANQHQERAKYFSKPKQEVIFEDAILLHDKSVMDLFLTFSQMMSQKQKELSNSQTVIEKEDYRIEDMMIVIERHFNLKKKTTLQEVFADCQTKSEMITLFLAMLELIKLHQITVEQDSNFSQVILRKEEK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: DML1_PICST
Sequence: MGEVVNLSLSQRANHVLTHLYNNQESHIPYKKNQPVNFFNNVFLSTSKTHTGHTNYAPRALVFDLRYGLGSLNKHEYHETPTNFDNIPQSDRFNLDKQIAKNQYQQNLDKGIASTEAESILSVENTKFWTDYNKLIYSPSSLNTLQNYDIGQSPEYGSHHNFPQIKFNTFEVGQKEFSDSTSNLDSQLDSFRRLLEQCDLLQGVNVVSELDSAWGGFTTSLLTEFIDEYFNGGISNTKNSIWIYGLHSQGPSGRSSINEAISRIKTTIELSKNSTLFFPINTAPFSKGIFSSDTIEDNILRGEHERKIVNDIKLKSIDSSKVTDINSLGSIISNVDISAYYNMSAPKPQDSSSGYIDLSVPTTVPTKTSSKVINEYFVKNYVIPTEQGKLEEKFAFKDKGIPSNVYRSRDITSIIKVDTFPYKIFNSQKQFNFYSEFNVSTDYRIELKAYKDLIKNVRLNSQQLMGIIEDKAELIEDISHILEHYTISNEPSDEESDDDY
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NDK1_ARATH
Sequence: MEQTFIMIKPDGVQRGLIGEVICRFEKKGFTLKGLKLISVERSFAEKHYEDLSSKSFFSGLVDYIVSGPVVAMIWEGKNVVLTGRKIIGATNPAASEPGTIRGDFAIDIGRNVIHGSDSVESARKEIALWFPDGPVNWQSSVHPWVYET
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  Plays a role in response to reactive oxygen species (ROS) stress.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Peroxisome. Nucleus. Cytoplasm.
Protein: BRK1_PROEX
Sequence: DKNKKPIRVGGRRPPGFTPFR
What is the function of this protein?
Causes constriction of the isolated rat ileum muscles (is 13-fold less potent than bradykinin (BK)), as well as degranulation of mast cells (is 7-fold more potent than BK).  In vivo, causes algesic effects.  Muscle constriction and algesic effects are partially mediated by bradykinin receptors B2 (BDKRB2).
What are the official names of this protein?
Protopolybiakinin-1, Bradykinin-related peptide, Protopolybiakinin-I.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADA24_MOUSE
Sequence: MVAMSEALVHARITLLQAWLRMLLFSSVWPPTWCAEYKGPPETVKPLRVIVSSKDMSLAGWMSYSLYFGGQRHIISMKSKNFLESRQLPVFTYNDQGVLFEDRPFVQNDCYYLGFVDGDLESMAALTTCFGGFQGILQINDTAYEIKPKSPSSTFEHLLYKIDSEKTQLRPMRCGLTDEEIAGQVRLQENGKSTRMQSIYGSWWSHGLYIKLALVIDHEQYLYRKKNTSLVIRDVLSIMQGINLFLLSVDINVVLLGLTIWTNGNPIPVQDIYALLPAFCTWKGTNLDSQIPYDIAHLFVNYTFSNYFGIAYVGTVCDKTFGCGIDSIAEDDFLTIGHIVAHEIGHNLGMSHDGILCTCGEESCLMSATMDSSQKLSNCSYEVLWAHMINKSCIHREPRPSDIFQLKVCGNGIVEEGEQCDCGSSENCRRNRCCMPSCTLRSKAKCDTGLCCNRKCQIQPSGTLCRARENECDLPEWCNGTSHECPEDLFVQDGTSCPGDGYCYEKRCNSHDVHCQRVFGQLAMKASDSCYKELNTRGDRFGNCGFINNEYVRCEISDILCGRIQCDKVGTLPILQNHYTIHWTHFNSVSCWSTDYHLGMKIADLGDIKDGTNCGPQHVCIARKCVNKPSWVNDCTPETCNMKGVCNNKQHCHCDVGWSPPNCQETGTGGSIDSGSPGNEVYEDEVVSKKDAPEKPNVIIWLLPIICVAVVLSVLFCLSGATKKSREAAASQPAEERVKPPYEGAEPSYETVKPPDEWANP
What is the function of this protein?
Plasma membrane protease present on mature sperm that may be involved in sperm function during epididymal maturation and/or fertilization.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 24, ADAM 24, Testase-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RSMC_HAEI8
Sequence: MISLESQVLERHLSFFDGKSVLFAGGISDNFPQTLASKCSSIQIWSCYFDYARTQSAVNFSVEFQGQADLIVYYWTKNKQEVNFQLIQLLAQASIGQEILIIGENRCGVRSVEKTLAPYGEIAKIDSARRCGLYHFSLQNKPHFELKNFWKTYQHPTIQDLTIYSLPGVFSAAELDTGTELLLSTIDNKIKGKVLDLGCGAGVIGSVIKKSSTNAQITMTDIHAMALESAHKTLSENQLQGEVYASDVFSDIEGKFDLIISNPPFHDGIDTAYRAVTELITQAKWHLNQGGELRIVANAFLPYPELLRQHFGDYEILAQTGKFKVYSVKN
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG1_EMENI
Sequence: MASTPSKSSRSSKEAYSEVAIGPYTRLDHIGKGSFATVYRGVQTKSRTFVAIKSVNLGKLNRKLKDNLAMEIDILKYLLHPHIVALLDCLETNSHIHLIMEYCALGDLSQFIKRRDSLKDHSYTRHMISKYPNVSGGALNEVIVRHFLKQLASALRFLRDKNLIHRDIKPQNLLLCPAPKPAPTQSEAEPQIVPLKGSETSFTPAVGLETLPLLKLADFGFARSLPATSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVVGKPPFRATNHVELLRKIETARDRIKFPEENPASDDIKALVRGLLKFNPVVRMTFADFFENDIITGPIPGLAAEDVPIPDRPPSPEVIPTESAEPQSVSDTIYPRNNDAEPKEDRYPPPHRYVPHNDRPQTPTSSSPMRRTRSGDRPSSAKQIPPAAAPPRPEAVSHATAPGRQELIGRHSSEQQAPGTVPVYKNVDKLKEERELAAQEVAFERDYVVVEKRAVEVNAFADQLAYDPRFHGKQTGALPRRQTTPALPTTQASSQNSPRKAVQVVSGRSRADSAHNRHASYERRYGQSPTSATSAISKALNMASGRLFGVGFSPPLNIAKGGRSPPLAYNPFPAYPTGHAGLLTMGDGARAQASPDEDTRTVKELEECATRSDVVYGFAEVKYKQLIPLAPSSQSYNSPNAPGTNFEEGELTPDAAVTLSEEALVLYVKALSLLAKSMDIAGAWWMRKNRAEALGESSFSRLEPVSIRINKVVQWVRSRFNEVLEKAEFVRLKLLEAQRRLPTDHPSHPNNLSLESAGSGTSVDVMVSPGVTAEKLMYDRALEMSRAAAINELTSEDLPGCEIAYVTAIRMLEAVLETDEVQPSGKGTDKVTLDGVQGEEREVLLKLVSKIRMRLATLRQKLAVLAKRQTPPSSGKMIPSNLAHATPATPATGMATPR
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase atg1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: YR23_CAEEL
Sequence: MDLKDGVEEEEGAGENGKGGTHAQRVSDTHLRCLPFLARKERETNFDTSMLSAGMNQLLDLEDYMFQRIQGPEEPSAETSVGGFCDDRLCQYGNMFSGYGACGTYFAPEAP
What are the official names of this protein?
Uncharacterized protein W02B3.3.
Protein: ATPF1_GRABC
Sequence: MLLGTVVTVLSTLPAIAYAMDPESPEHEGMPQLNFANPLTTSQVVWMALILLAFYLLLSKWALPQVSQVVDDRNASIMGDLDSAHLAKAEANAAVEEMNDAIRRANLEGQAEIEKTVSAAKAKAQQEAAEAHARLERQLADAEARIASSRDTAMGALRDVATDTTQALIARLTGQFPAQDTVEQAVGQALAARS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SWC4_USTMA
Sequence: MTSNDVRDILSLPERPASQPSSSAQASGSSSRNRKSSGSNNPHPSSAASASRPKPKYDGMTRELFALLGDNAPSLAMTHGLDAEGKPVMGLGGLFKPKFKRRKEKVRQWRWTPFLNSARDDTQIDDDVPEINHGLILHHWAPARSFSTTAADGISAEDADIDTKYQYAAFNTTSGVYSYSNDEYIQHLRDDDWTKEETDYLMELCTAYDLRFVVIHDRYDWAAAQASFLAGSTSAVPQPVKERSMEDLKVRYYAICRRLIRSRISTDDVETRQMLLSTYAFDKQREVERKKAVARLYTRTPEQLAEEEALYVEIRRIEQNEAKYASEREELLRLLGGWESLPSSSPHAVAAAGSGIASLLGAEEDSTAKGRAGSANKKRKLQQIEDNGTPGADDAGSSTGATAAATSRPSANLTSKQRAELRQAQFDEMQCIVRFASNANATTDASAGGIAGPAAVSAASSSTRPPYAYLVGTASTLPAVTSNPANPTSGHGVYLRSSRMLAPRPNLVLRTTQVLSESDPPVGPRLIFPTAKNVEKWENLIGAVTTGLEMRKQLERVNAELRIAKQRIAAALHPNRMADKSEASAEAVESRSAAPTENSIAATTSTHAQITIKTE
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
SWR1-complex protein 4.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.