PharMolix/UniProtQA huggingface dataset:
Protein: PHOS_BOVIN
Sequence: MEKAKSQSLEEDFEGQASHTGPKGVINDWRKFKLESEDSDSVAHSKKEILRQMSSPQSRDDKDSKERFSRKMSVQEYELIHKDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELESGEQFLETIEKEQKITTIVVHIYEDGIKGCDALNSSLICLAAEYPMVKFCKIKASNTGAGDRFSSDVLPTLLVYKGGELLSNFISVTEQLAEEFFTGDVESFLNEYGLLPEKEMHVLEQTNMEEDME
What is the function of this protein?
Inhibits the transcriptional activation activity of the cone-rod homeobox CRX (By similarity).  May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism.
What are the official names of this protein?
Phosducin, PHD, 33 kDa phototransducing protein, Protein MEKA.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Protein: P5CR_MYCLE
Sequence: MLSSMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRARYLADTYSVLVTSVTDAVENAMFVVVAVKPTDVESVMGDLVQAAAVANDSAEQVLVTVAAGVTITYLESKLPAGTPVVRAMPNAAALVGAGVTVLAKGRFVTGQQFEDVLAMFDAVGGVLTVPESQMDAVTAVSGSGPAYFFLLVEALVDAGVAVGLTRQVATELAAQTMAGSAAMLLERMDQDRHSAEVAPLGAQVDVPAAQLRATITSPGGTTAAALRELERGGLRMVVDAAVQAAKIRSEQLRITSE
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_ROTTU
Sequence: MAYRKRGARRETNLKQDDRMQEKEENKNITNSIENKSTAKTQLSEKVLSQKEEIITDNQEEVKIADEVRKSNKEESKQLLEVLKTKEEHQKEVQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKLFRIFEPKQLPIYRANGERELRNRWYWKLKRDTLPDGDYDVREYFLNLYDQVLTEMPDYLLLKDMAVENKNSRDAGKVVDSETAAICDAIFQDEETEGVVRRFIAEMRQRVQADRNVVNYPSILHPIDHAFNEYFLQHQLVEPLNNDIIFNYIPERIRNDVNYILNMDRNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKELVSTEAQIQKMSQDLQLEALTIQSETQFLTGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVVPNDMFIRESLVACQLAIINTIIYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFVNNNQFRQVVIDGVLNQVLNDNIRNGHVINQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLAYNYETLMACITMNMQHMQTLTTEKLQLTSVTSLCMLIGNATVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAANRLNLYQKKMKSIVEDFLKRLQIFDVSRVPDDQMYRLRDRLRLLPVEIRRLDIFNLILMNMEQIERASDKIAQGVIIAYRDMQLERDEMYGYVNIARNLDGFQQINLEELMRTGDYAQITNMLLNNQPVALVGALPFITDSSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWIPTSTTKVYKQVPQQFDFRASMHMLTSNLTFTVYSDLLAFVSADTVEPINAVAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: CAAP1_HUMAN
Sequence: MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRSTDSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEKDIEKSVNEILGLAESSPNEPKAATLAVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPA
What is the function of this protein?
Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.
What are the official names of this protein?
Caspase activity and apoptosis inhibitor 1, Conserved anti-apoptotic protein, CAAP.
Protein: EXOS8_HUMAN
Sequence: MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC8 binds to ARE-containing RNAs.
What are the official names of this protein?
Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus.
Protein: LUP5_ARATH
Sequence: MWRLKVGEGKGKDPYLFSSNNFVGRQTWEFDPKAGTREERTAVEEARRSFFDNRSRVKPSSDLLWKMQFLKEAKFEQVIPPVKIDGGEAITYEKATNALRRGVAFLSALQASDGHWPGEFTGPLCMLPPLVFCLYITGHLEEVFDAEHRKEMLRYIYCHQNEDGGWGFHIESKSIMFTTTLNYICLRILGVGPDGGLENACKRARQWILSHGGVIYIPCWGKVWLSVLGIYDWSGVNPMPPEIWLLPYFLPIHLGKAFSYTRITYMPISYLYGKKFVGQITPLIMQLREELHLQPYEEINWNKARHLCAKEDKYYPHPLVQDLIWDALHTFVEPLLASWPINKLVRKKALQVAMKHIHYEDENSHYITIGCIEKNLCMLACWIDNPDGNHFKKHLSRIPDMMWVAEDGMKMQCFGSQLWMTGFAVQALLASDPRDETYDVLRRAHDYIKKSQVRDNPSGDFKSMYRHISKGGWTLSDRDHGWQVSDCTAEAAKCCMLLSTMPTDITGEKINLEQLYDSVNLMLSLQSENGGFTAWEPVRAYKWMELMNPTDLFANAMTEREYTECTSAVLQALVIFNQLYPDHRTKEITKSIEKAVQFIESKQLRDGSWYGSWGICFTYGTWFALCGLAAIGKTYNNCLSMRDGVHFLLNIQNEDGGWGESYMSCPEQRYIPLEGNRSNVVQTAWAMMALIHAGQAKRDLIPLHSAAKFIITSQLENGDFPQQELLGASMSTCMLHYSTYKDIFPPWALAEYRKAAFIHHADL
What is the function of this protein?
Multifunctional enzyme that converts oxidosqualene to tirucalla-7,21-diene-3beta-ol and two other triterpene monoalcohols.
What are the official names of this protein?
Lupeol synthase 5, AtLUP5.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: DNMT1_PARLI
Sequence: MPSKTICDQVIPPNVRDRVQELDGDLNDGLITEKGYVKKKSKILFEHLSPDIQTKLKGLEDELKDEELTEKGYLNKVQSILAKFIETCSPVNGDTKEEASSNGKDDEKAESTVANGTTSNGSTTNGSSGSSKANGHTNGGYVQSSSQEETGTSQSEEEMDMDTPTSGKGGSKKKKKSKGSGGGDAGKGRKRKVLGDDERDGVEKKEGEKKDVEGEEGEEAKEESATPDEKTLRTSKRKRSPKADAKQPSIMSMFTKKPAKKEEEKMEESSSMEVDKKEMENGDNGKKEEEEPSGPGGKRIKKEEEEEEKAKVEPMSPSRDLRHKANHETAESKQPPLRCKECRQLLDDPDLKIFPGDPEDAREEYITLTDPRLSLLTGDEGDAMSYDERLQHKITNFCVYDKSTHICAFDRGMIEKNKELYFSGYVKPIYDDNPSTEGGIPTKRIGPINEWYTTGFDGGHKALIGFSTAFAEYIVMSPSEEYKPFWTAVQEKIYMSKILIEFLQNNVDPVYEDLLTQIETTVPPEGCNRFTEDSLLRHAQFVVEQVESYDDAADRDEVLLITMPCMRDLIKLAGVTLGKRRAARKAAAVKKDKKPVFTMATVTPLVSHIFDAIFKDQIADEMKAAASERKKRCGVCEICQAPDCGKCTACKDMIKFGGSGKAKQACKDRRCPNMAVQEADENDIDEMDNSSNKENKDEKKAKKGRKLETPLKKKKRAKVTWLDEPTEVTEERAYYKAAMLDDEKIEIGDCVLIHPDDPTKPLFMARVIYMWQESQGEMMFHAQWFVYGSETVLGETSDPLEVFPIDECQDTYLGSVNAKCTVIYKAPPNDWSMIGGIDDPETDHVIKEDDGKTFFYQKWYDPELARFEDYEVLMAPDDIPAHRFCSCCLKNERAQEKETARPGAKLEDQDDSSKVLYSSWHYKGNEFQIGDGVYLLPEVFSFNIKQKVVTKKPVSKKDVDEDLYPENYRKSSEYVKGSNLECPEPFRIGKIISIYTTKSNSTVRLRVNKMYRPEDTHKGRTAAYQADLNVLYWSEEEAVTELEVVQGKCSVVCAEDLNVSTDEYSAGGPHKFYFREAYDSERKCFEDPPSKSRSTRMKGKGKGKGKGKAKGKIAVEKEEEKESTETPFNKLKCLDVFAGCGGLSEGFHQAGICESSWAIEKEEPAAQAYRLNNPGSTVFSDDCNELLRLVMQGEKTSRTGQKLPQKGDVELLCGGPPCQGFSGMNRFNSREYSKFKNSLISSYLSYCDYYRPRFFLLENVRNFVSYKKNMVLKLALRCLIRMGYQCTFGILQAGQYGVPQTRRRAIILAAAPGEKLPFYPEPLHVFSSRACSLSVMIGEKKIESNNQWCLSAPYRTITVRDTMSDLPTINNGAQKLEISYDGEPQSDFQKKIRGNQYQPILRDHICKDMSSLVAARMKHIPLAPGSDWRDLPNIPVTLKDGTTCRKLRYTHKDKKNGKSSTGALRGVCSCAEGDACDPSDRQFSTLIPWCLPHTGNRHNNWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRFFGSILDKHRQIGNAVPPPMAAAIGMEIKVCLQTKTKRDQERAALEPVKEETEESMD
What is the function of this protein?
Methylates CpG residues.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase PliMCI, DNA methyltransferase PliMCI, DNA MTase PliMCI, M.PliMCI, Dnmt1, MCMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METK_DEHM1
Sequence: MSQTFGNSSKYLFTSESVTEGHPDKICDQISDAVLDAIIAKDPNAHVACETAVTNGLVVVMGEITTSCYVEIPELVRGVIKDIGYTKPEYGFDDRTCGVLTSINRQSPDIALGVNKSQEAKSGQVDELDLTGAGDQGMMFGYACTETPEYMPLPISLAHRLSKRLSEVRKNGTLAYLRPDGKSQVTVEYHNGEAKRISSVVIGAQHDPDVTTEKIQADIIREVIKPIIPTNLLDENTEYYVNATGRFVVGGPVSDTGFTGRKILVDTYGGFARHGGGAFSGKDPTKVDRSACYMARYIAKNLVAAGLADRLEIQVAYVIGVAHPLSVSIETFNTARMSHEDILSIIQKHFDLRPEAIIRNLGLRRPIYRQTAAYGHLGRPELDLPWERLDKVDAIKATMESLSVSK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDZD7_HUMAN
Sequence: MAQGFAVGFDPLGLGDLSSGSLSSLSSRGHLGSDSGSTATRYLLRKQQRLLNGPPRGIRASSPMGRVILINSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVKVLTSSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCGSTPSDTSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSCASSAPYSSGSLPSDRMDICLGQEEPGSRGPGWGRADTAMQTEPDAGGRVETWCSVRPTVILRDTAIRSDGPHPGRRLDSALSESPKTALLLALSRPRPPITRSQSYLTLWEEKQQRKKEKSGSPGEKGALQRSKTLMNLFFKGGRQGRLARDGRREAWTLDSGSLAKTYPRLDIEKAGGVGPVQKFVTWRLRRDQERGRALLSARSGSPSSQLPNVDEQVQAWESRRPLIQDLAQRLLTDDEVLAVTRHCSRYVHEGGIEDLVRPLLAILDRPEKLLLLQDIRSVVAPTDLGRFDSMVMLVELEAFEALKSRAVRPPALRPARQDTPPKRHLITPVPDSRGGFYLLPVNGFPEEEDNGELRERLGALKVSPSASAPRHPHKGIPPLQDVPVDAFTPLRIACTPPPQLPPVAPRPLRPNWLLTEPLSREHPPQSQIRGRAQSRSRSRSRSRSRSSRGQGKSPGRRSPSPVPTPAPSMTNGRYHKPRKARPPLPRPLDGEAAKVGAKQGPSESGTEGTAKEAAMKNPSGELKTVTLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLSGALQAGFELVAVDGENLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPSPRPSPSDSSALTDGGLPADHLPAHQPLDAAPVPAHWLPEPPTNPQTPPTDARLLQPTPSPAPSPALQTPDSKPAPSPRIP
What is the function of this protein?
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links.  Blocks inhibition of adenylate cyclase activity mediated by ADGRV1.
What are the official names of this protein?
PDZ domain-containing protein 7.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus. Cell projection, stereocilium. Note=Localizes at the ankle region of the stereocilia.
Protein: RAE1C_MOUSE
Sequence: MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKAPTPADPLWYEAKCLVDEILILHLSNINKTMTSGDPGETANATEVGECLTQPVNDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQTPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWNDDGDLVQRLKYFIPECRQKIDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM
What is the function of this protein?
Acts as a ligand for KLRK1.
What are the official names of this protein?
Retinoic acid early-inducible protein 1-gamma, RAE-1-gamma.
What is the protein family that this protein belongs to?
Belongs to the NKG2D ligand family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ARODE_CHLTR
Sequence: MLCTTISGPSFLEAKKQILRSLKECHCFEMRVDLLSVSCLELKKLMELAPISILAWKKPESCSQADWIDKMQSLAELNPNYLDLEKDFPEEDMIRIRQLHPQIKIIRSLHTSEHTDIIQLYAHMRSSAADYYKFAVSSSSTTDLLDICHQKRSLPENTTVVCLGGMGRPSRILSPILQNPFTYARSTGSSPVAPGQFSLKHHYFYNFASLSAQSPICALIGDTSRSIGHLTHNPFFSQLGVACPYIKLPLTPQELPKFFSTIRTQPFLGVSVTSPLKTAVLPFLDKQAPSVKASGSCNTLVIRQGEIEGHDTDGEGLFSVLMQHQIPLNNQRVAIIGAGGAAQSIATRLSRANCELLIFNRTKAHAEDLASRCQAKAFSLEELPLHRVSLIINCLPPSCTIPKAVAPCVVDINTIPKHSTFTQYARSQGSSIIYGHEMFTQQALLQFRLWFPTLSFKHLEKTFIRRAAVLASLFSIAP
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of the aromatic amino acids biosynthetic pathway.  In the first reaction, the AroD domain catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate; in the second reaction, the AroE domain catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate biosynthesis protein AroDE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Protein: SECA_RIPO1
Sequence: MLKTLFGDPNARKLKKFQPFVTEVNLLEEEIQKLSDEELKYKTVEFREALDKARNDEELEDILDEILPEAFAVVREAGIRVLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVATLPAYLNGLTGKGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQGGMNPEERKKNYGCDITYTTNSELGFDYLRDNMATAMAEVVQRPFNYCIIDEVDSILIDEARTPLIISGQVERPTEKYLQAAAIAAQLLKQESEDDPGDYEVDEKARNVLMTDAGFEKAEQLLNVQDLYDQDNPWAHYIFNAIKAKELFTKDVNYMIRNNEIVIVDEFTGRVLPGRRWSDGLHQAIEAKEGVEIQRETQTLATITYQNFFLLYPKLSGMTGTAKTEETELEKVYNLQVTIIPTNRISRRYDLPDVVYKTEDAKWQAVAGEVEELHHQGRPILVGTTSVEKSEVLSKLLQQKKIHHNLLNARPENVERESEIVAQAGRKGAVTIATNMAGRGTDIILGGNADYMARLKIREYLMPQIVMPEDDDLMAGVSGNGGRRPQGFGTSKKKGKNWSPSDADIFPTKMSQETEEILKEAVKFAVEQYGQQSLTELEAEEKIAIASENAPTDDSVVEKLRVVYKAIRKTYETVTDQEHDEVVELGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESQMLTRSLEGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVLQYAEKTMDEIVDAYVNPELPPEEWDIPNLVGKVKEFVYLLKDVTPQDMEDMTVSEMKIFLHEEVRKAYDIKEYEVDQIRPGLMREAERFFILQQIDTLWREHLQTMDALRESIGLRGYGQQDPLIEYKQEGYEMFLEMMIDIRRNVVYSLFQFQPQGQPQTV
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: NGDN_MOUSE
Sequence: MAAPEVLESDVSSSITLLKNLQEQVMAVTAQIQALTTKVRAGTYSTEKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQGHPAVLRLVEIRTVLEKLRPLDQKLKYQIDKLVKTAVTGSLSENDPLRFKPHPSNMVSKLSSEDEEESEAEEGQSEASGKKSAKGSAKKYVPPRLVPVHYDETEAEREQKRLEKAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRVNYEESMMVRLSVSKREKGLRRRASAMSSQLHSLTHFSDISALTGGTAHLDEDQNPVKKRKKLPKKGRKKKGFRRRW
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1* (By similarity).  Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner (PubMed:16705177).
What are the official names of this protein?
Neuroguidin, EIF4E-binding protein.
What is the protein family that this protein belongs to?
Belongs to the SAS10 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome, centromere. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, filopodium. Note=Translocated from nucleolus to nuclear foci in response to UV damage (By similarity). Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.
Protein: SYFAA_XENLA
Sequence: MADNSVSEQLLQRLQDGGSKGVDSLELAALLGVEHQQVVGAVKSLQCLGEIIQAEQRSSKKWELSSEGEEIGREGSHEARVFQTLPKEGLLQAQLMKQPFSKVGFSKAMSNKWIRLDKAAEGGPRIYRVVDSIEDTVKEKLQLILKGRADDVNEKDRNELKKRKLVNEVTVKSYWVTKGSGFSTSITKQETDLTPEMIASGSWREKQFKGYNFDALGVMPECGHLHPLLKVRTQFRQIFLEMGFTEMPTNNFIESSFWNFDALFQPQQHPARDQHDTFFLQDPALATEFPMEYLERVKKVHSEGGYGSQGYKYDWSIHEAQKNILRTHTTAVSARMLYKLALQKDFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADRGLTLGNLMGVLKEFFHKLGITKLRFKPAYNPYTEPSMEVFSYHEGLKKWVEVGNSGLFRPELLLPMGLPEDVNVLGWGLSLERPTMIRYGIKNIRELVGHKVNLQMVYDSPICRLDA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit A, Phenylalanyl-tRNA synthetase alpha subunit A, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_STAA9
Sequence: MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDFTLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3BP5L_HUMAN
Sequence: MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPEDMEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDHVSLDGQELGTRSGGRRGSDGGARGGRHQRSVSL
What is the function of this protein?
Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
What are the official names of this protein?
SH3 domain-binding protein 5-like, SH3BP-5-like.
What is the protein family that this protein belongs to?
Belongs to the SH3BP5 family.
Protein: CSK2C_NEUCR
Sequence: MDDFVSESESDYASYWRDWFISSRGNEYFCEIDEDYITDRFNLTGLNTEVQYYQYALDLITDVFDLDCDDDMRETIEKSARHLYGLVHARYIVTTRGLQKMFEKYKKADFGKCPRVMCSSHPLLPMGLSDVPNSKPVKLYCARCEDIYNPKSSRHAAIDGAYFGTSFHNIFFQVYPTLVPAKSVERYIPRCYGFKVHAAAALVRWQNSQRDEMRRRLRKLEVESGFKDAEDEAELDDDDEEEEEEEEEEEELAAMDEAEGAQQQHAAAAAGTATGGVAAGGEGVH
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2 (By similarity).  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).
What are the official names of this protein?
Casein kinase II subunit beta-2, CK II beta-2.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: KTHY_CHLP8
Sequence: MLITFEGIDGAGKSTQVVKLKRHLQERGREVLTLREPGGTPVAEQIRELLLESHNDITSIAELLLFSASRAELMEKIIVPALEDGCDVILDRFFDSTTAYQGYGRGLNLDMLAEINRIASHGIRPDITFYLDLTPEDALLRKFSEKSLPLAFESEELDRMENSGLEFYQRVRAGYHAILEAEPQRIIMIDALLTPQEIHRKILSALQALEVPEDGKR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: HPRK_LACPL
Sequence: MAGSVTVADLVKNTRLDVYHGADLLEKKDITTSDISRPGLALTGYFNYYPRERVQLLGKTETAYSKNMSHDERLMIFRKMCQLTTPAFVISTGLPVPEELVQAGEENGVPILGTKMTSSRILSNMTNYLEGKLAERQSVHGVLVDIYGLGVLITGDSGVGKSETALELVKRGHRLIADDRVDVYQQDEQTLVGEAPAILNHLLEIRGIGIIDVMNLFGAGAVRQDTDIDLIVHLENWTPDKQFDRLGNGEQNRKFFDVEVPEISIPVKTGRNLAIIIEAAAMNFRAESMGYDATKVFDDNLNKLIKTNSVHDSHK
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: SIR_SOYBN
Sequence: MTTSFGPATTSAPLKDHKVQIPSFHGLRSSSASALPRNALSLPSSTRSLSLIRAVSTPAQSETATVKRSKVEIFKEQSNFIRYPLNEDILTDAPNISEAATQLIKFHGSYQQYNREERGSRSYSFMIRTKNPCGKVSNQLYLTMDDLADQFGIGTLRLTTRQTFQLHGVLKKDLKTVMGTIIRNMGSTLGACGDLNRNVLAPAAPLARKDYLFAQQTAENIAALLAPQSGFYYDIWVDGEKILTSEPPEVVQARNDNSHGTNFPDSPEPIYGTQFLPRKFKIAVTVPTDNSVDILTNDIGVVVVTDDDGEPQGFNIYVGGGMGRTHRLETTFPRLAEPIGYVPKEDILYAVKAIVVTQRENGRRDDRKYSRLKYLISSWGIEKFRSVVEQYYGKKFEPFRALPEWEFKSYLGWHEQGDGKLFYGLHVDNGRIGGNMKKTLREVIEKYNLNVRITPNQNIILTDVRAAWKRPITTTLAQAGLLQPRFVDPLNITAMACPAFPLCPLAITEAERGIPNILKRIRDVFDKVGLKYSESVVVRITGCPNGCARPYMAELGLVGDGPNSYQIWLGGTP
What is the function of this protein?
DNA-binding protein that binds to both double-stranded and single-stranded DNA without significant sequence specificity to reversibly repress the transcriptional activity of chloroplast nucleoids by promoting DNA compaction and possibly regulate DNA replication.
What are the official names of this protein?
Sulfite reductase [ferredoxin], chloroplastic, GmSiR, Nucleoid DNA-compacting protein of 68 kDa.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma, chloroplast nucleoid. Plastid, chloroplast stroma. Plastid stroma.