PharMolix/UniProtQA huggingface dataset:
Protein: RGS9_HUMAN
Sequence: MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGSDVLQWIVQRLWISSLEAQNLGNFIVRYGYIYPLQDPKNLILKPDGSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYNFLNQKMNYKWDFVIMQAKEQYRAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVPTGSGTCLMDSEDAGTGESGDRATEKEVICPWESL
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to GNAT1.  Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 9, RGS9.
What are the subcellular locations of this protein?
[Isoform 3]: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP.
Protein: VIRB6_BRUAB
Sequence: MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLASATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAMTSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
What are the official names of this protein?
Type IV secretion system protein VirB6.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZNF77_HUMAN
Sequence: MDCVIFEEVAVNFTPEEWALLDHAQRSLYRDVMLETCRNLASLDCYIYVRTSGSSSQRDVFGNGISNDEEIVKFTGSDSWSIFGENWRFDNTGDQHQIPQRHLRSQLGRLCESNEGHQCGETLSQTANLLVHKSYPTEAKPSECTKCGKAFENRQRSHTGQRPCKECGQACSCLSCQSPPMKTQTVEKPCNCQDSRTASVTYVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTHAGA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 77, ZNFpT1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YGFZ_SALCH
Sequence: MAFISFPPRHPSSSARLPLTLIALDDWALSTITGVDSEKYIQGQVTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVLEAQLTELKKYAVFSKVVIAPDDERVLLGVAGFQARAALANVFSVLPNSENQVVRDGASTLLWFEHPAERFLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPAIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRTGAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PILF_PSEAE
Sequence: MTVRAALVFLLAVGLTGCVTSGDQNPLKTDKGRDEARDAYIQLGLGYLQRGNTEQAKVPLRKALEIDPSSADAHAALAVVFQTEMEPKLADEEYRKALASDSRNARVLNNYGGFLYEQKRYEEAYQRLLEASQDTLYPERSRVFENLGLVSLQMKKPAQAKEYFEKSLRLNRNQPSVALEMADLLYKEREYVPARQYYDLFAQGGGQNARSLLLGIRLAKVFEDRDTAASYGLQLKRLYPGSLEYQEFQAEK
What is the function of this protein?
Essential component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers (PubMed:8973346).  Plays an essential role in the outer membrane localization and assembly of PilQ into secretins which are dodecamers of PilQ (PubMed:23547883, PubMed:18776008).
What are the official names of this protein?
Type IV pilus assembly protein PilF.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MTMRA_DANRE
Sequence: MFSGKQTKPTFKSYLPPLQTDLKKSPQLPIKKLEAKLLPGEIVVNEANFVRKCIGADSGQDDLWGKLVCTNFKVSFISHNSLPQQRFQCTHRLLGEHDIPLACVEQVVTVNDVKGKQKILGSNQKLKFNPTELILYCKDFRIIRFRFDEAGPESAKKVCLAIAHYSHPADPQLLFGFEYVGKRYHGSAGERVNGVDPGGGLQTPLFDCSSDWDREIKRTGASEWRVCTINQGYFISPSLPEFFVVPVSLADQDLKQYACCFYSQRIPLWCWNHPSGSALVRMSNISDPQQQRKVEQRISSAITKSHPLRSDVFKSDLDKNLPNIQDIQAALLKLRQICVIESFEESEEKWLSSLESSRWMEYVRTFLRHAVEVVYMLESRHVSVILLEKEDRDLSCVISSLVQLMCDPHCRSLHGFQALIQKEWVMAGHRFLDRCNHLKKSDKEELWNQYPAAFEFTEVYLTVLGDSMWVPVFSTFLFNCPRQRAEHSRDFASSKSIHLGQDQALRFPPVWDWSQQFSLKDQTLFNNPLYVGKIATCLQNGTVKTFTHRRSKKNYSSTVRGLPSLMRNGSLGPNDTLTRRNSLVLRLRSDLSQVREQPETPSERFVRDFFSRAVDLQGLLLPQLLPSHLSVWKLYFLRWVPEAQIPHGGPVTAFHKLSVLTDEIEMLQNQLRQYKGAAGTANTSHAEHSKMYFKATSTPQQCPAPPGYLSSSFPFSPVGNLCRPGILGTPLSKFLNGAKIWLSTETLANETI
What are the official names of this protein?
Myotubularin-related protein 10, Inactive phosphatidylinositol 3-phosphatase 10.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein: Y1129_THEM4
Sequence: MIISTTDKIPGYKIKEITGIVMGNIVHSKHLGKDIAAAFKTLAGGEIKSYTEMMTEARNKAIERMIDEAEKLGADAIVSVRFSSSAIMSGAAEILVYGTAVKLLPKDI
What are the official names of this protein?
UPF0145 protein Tmel_1129.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL9_BORDL
Sequence: MKVILREDFINLGKEGDIVDVKDGFARNYLLPKGFAVFSNKHNIDIFSQKKRAILKRQETRRKMAVELKEKLDKVNLEFIMQSNDSGKLFHSINSSNIADELLKLGFEIERRKIDMHHGALKAFGTYNVTIKLYEGISSVITVEIKREEKKNSLKKSKSVEKEV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DPO3B_RHOCA
Sequence: MWRPAKXPALRCVATDGHRLARIDAVLPEGANGMPGVIVPRKTVNELRNVLDDDEAQIAVSVSETRCALA
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHZ1_PHANO
Sequence: MSAQQDNQMQGVQDPAAEGKGKGKAPEDNTVEESMDDDSSDESGAEEQVLEEPDEDNMEEIDTANVIGSRTRGKNIDFAKANQELGDDDEEDDDEDFVDPDDEMKD
What is the function of this protein?
Forms a chaperone-bound H2A. Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A. Z histone replacement in chromatin.
What are the official names of this protein?
Histone H2A.Z-specific chaperone CHZ1.
What is the protein family that this protein belongs to?
Belongs to the CHZ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_BORBZ
Sequence: MFKKVENKANFPKIEEKILKFWNDNKIFEKSIKQREGCEEFTFYDGPPFATGLPHFGHFVPNTIKDIIPRYQTMQGKYVKRNFGWDTHGLPVEYEVEKKLGISGKYEIENYGIENFNKECRKIVLRYTEEWKNIILRLGRWVDFEKGYKTMDISFMESVWWVFKNLYEKGLIYESYYVLPYSPKLATPLSNFEVNLGEYKEVNDPSLTIKFKIKDKNEYLLVWTTTPWTLPSNLGIAVGQEIEYSKIFDKTKEEILILGSKKLNSYYDDENSYTIIEKFKGSKLEGIEYEPIFNYFLEQKDKGAFKVHTADYVTTDDGTGIVHIAPFGEEDYKILKKHTNVDIIDPLDAECKFTNQVKDFKGLFVKDADKKIIENLKLRNFLFKRENYLHRYPFCYRTNCPIIYRPISSWFVNVEKIKTKLLEVNEKINWMPAHLKKGRFGKWLENAKDWAISRNRFWGNPIPIWICSKTGKKICIGSKKELENLSGQKIEDLHKDQIDKITWPSKDGGKFIRTSEVLDCWFESGAMPYASNHYPFTNEINFKNIFPADFIAEGLDQTRGWFYTLTILGTALFENTAFKNVIVNGLVLSSDGRKMSKSFKNYTDPMQVINTFGADALRLYLIMSPVVKADDLKYSDNGVRDVLKNIIIPIWNAYSFFTTYAIIDKFKPPKNISLAKNNNLDKWIISELESLKKILNTEIDKYNLTKSIESLLEFIDKLNNWYIRRSRRRFWKSENDKDKNDAYETLYYAIKTLMILLAPFIPFITEEIYQNLKTDEDKQSIHLNDYPKANENFINKTIEEKINLARKITSMARSLRSLHNIKIRMPISTIYIVTKNQNEQNMLMEMQEIILDEINAKEMKIKANEEELITYKAKANFKELGKKLGKDMKAVSAEISKLKNEDIIKIINGTSYEIKVANAKHYLSLNDIILEREEKENLKVINEESITIGIDSLITKELYLEGLTREFVRQIQNLRKEKNFDVSDRINLYIENSETLKEMLNKFEKYIKTETLALNIILNKSKLEKKINLADDIFTLIGIEKC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP_PSHV1
Sequence: MSSTANSAAHEHAEKTIEADAATGAAEDTSAQLGAERGATRFDIVLGKRGCELAAPVLRAVKCLITGAFLVMRKYSVVVYCATERGLVYVDLGWTIFDQYDFLPGGSDDPLLFSVATPQNGFLLDFLCDPPKKCAQDPVLSARFLVTDSDDPEEARELLKLIVTRESGTSTKIKRAAQTDERIYMPTANSACQVALEPYSHTEITKWLGALPKDAGVKVSISDTALGLERIGCAADSVSFNAQWMDRRADRVTSCDILAKLTGVGPDAGKRSLSARSALKKLKENRVVAVHSGSGWVHSELGWPESVRVRSAQSLKKALQWLKIGAWGVPNLVFYKDKVTGLGVELSGRGEEDLWGCILFFDSEEMDDLTAQEFQEPEDCAEADYGAVSESDDAAAETHRGADGIDGADEEDSCPDMMLISATTLTQQPGRKRAPGATLQQSAQPSSPATHRKQKRPAGAARTGAGDTEQNCVHDGEASLRAPCPASNDDQEPANKRGKR
What is the function of this protein?
Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit.  Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA.  Facilitates the origin-binding protein UL9 loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).
What are the official names of this protein?
DNA polymerase processivity factor, DNA-binding protein UL42, Polymerase accessory protein, PAP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase processivity factor family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NUSB_SYMTH
Sequence: MSRRKARELALQALFQMDIAGTDPDTAVAQALTRETEPDWAPDRLEEESAEFARRLVRGAWQHREESDRLIAQYARGWRVERMAAVDRAILRMAVYEIVHSEDVPDSVAVAEAVELAKTFSTADSSRFVNGILGSVIRGMKGAAGADEAVSRD
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AROK_BACFR
Sequence: MIRIFLTGYMGAGKTTLGKALARELHIPFIDLDWYIEERFHKTVGELFSERGEASFRELEKNMLHEVGEFEDVVISTGGGAPCFFDNMEYMNRVGTTVFLDVDPKVLFSRLRVAKQQRPILQGKKDDELLDFIVQALEKRAPFYRQANYIYCADKLEDRSQIETSVQQLRKLLNLHIAS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNTA_DICDI
Sequence: MSSSEEDDGYVPFSKRPEWSDVKPLAQDDGPHPICPILYSEVFKDKMNYFRAILKSKEKSLRVLDLLEEVIQENPSNYTIWYYRREVLKAIEQDETIEYDIQQEMNLLNDMGETDPKNYQIWNHRRFIVEKYIGSDNKEKEFLSGVLLEDAKNYHAWSHRQWLLKTYRDWNGELAMVDKLLSLDHRNNSVWNHRFFVISNLNPSPFPLSLIEREVEFAFNHIRHSPNNESPWSYLKGLFKGQKISTIYPSLLDILLEMKSKYIGCSHVNSIILDIYQEQNTKISLENSLNICKLLSETIDPIHKNYWNFKYNTISDQLKLIN
What is the function of this protein?
Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  The alpha subunit is thought to participate in a stable complex with the substrate.  The beta subunit binds the peptide substrate (By similarity).
What are the official names of this protein?
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: METE_THEVB
Sequence: MTIQTATLGYPRIGKNRELKKALEAFWSNQLDAEALLKTAQDIELQNWQKQLEVGIDRIGIGDLSLYDSVLDWSIRFGIIPERYRSFTGLEQYFAMARGKDGIPALEMTKWFDTNYHYLVPEISEAFQPTDFSDFLETVRRAQTLLGDRAVPIVLGPLTLLRLSRLETNLEQAVSYLRDRYLILLRELKNLGVVEVQIHEPALVLEEADSFKSFYQSTFDTLRQANLPLHLVTYFDDLGAAWPWVMELPVTCISLDFTRGHNLALLKEYGFPADKQLGVGIIDGRNIWKIRPESVLSTLETIQSITANIRLHPSSSLQFVPYDAKREVKLPEPLRDVLSFAEQKLDEVVLLARVLNSNDGTNREILMKNPELTAIQAQWKAFEQFSPVNPTVQARLRNLSVRDLERPLPYEQRRTLQPTLPPLPTTTIGSFPQTAEVRQLRVKLKRHEITQAEYEAAIDEEIAKCVRLQEEVGLDVLVHGEFERSDMVEFFGQQLSGFAFTEHGWVQSYGSRCVRPPIIYGDIARPQPMTVREFKVAQSLTDKIVKAMLTGPVTMINWSFTRTDIPRSEQAMQIALALRDEVADLEAAGAKMIQIDEPALREGLPLKAERWNEYLSWAVDAFRLAAGVAKPETQIHTHMCYSEFGDIIEHIERLDADVLSIENSRSNNETLFQITDAGYRHQVGVGVYDVHSPAVPSVEQLVQQLRTSVANLAPEQIWVNPDCGLKTRHWEEVIPSLKNMVEATKTIRQEVMQSKNNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: LSM3_MOUSE
Sequence: MADDVDQQQTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLRVG
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm3.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_PSESM
Sequence: MARTTPISRYRNIGIVAHVDAGKTTTTERVLFYTGKSHKMGEVHDGAATTDWMVQEQERGITITSAAITAFWQGSEKQHKDQYRFNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRIVYVNKMDRAGANFLRVIAQIKQRLGHTPVPIQLAIGAEDNFQGQIDLMAMEAVYWNDSDKGMVPVRKPIPAELQELADEWRGNMVEAAAEASEELMNKYLEGEELTNEEIKAALRQRTIAGEIVLAVCGSSFKNKGVPLVLDAVIDYLPAPIDIPAIKGSDPDNEEILMERHADDSEPFSALAFKIATDPFVGTLTFVRVYSGVLASGDGVINSVKGKKERVGRMVQMHANAREEIKEVRAGDIAALIGMKDVTTGETLCNADKPIILVRMDFPEPVISVAVEPKTKDDQEKMGIALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDILVDRMRREFNVEANIGKPQVSYRERITKNCEIEGKFVRQSGGRGQFGHCWIRFAPADEGQEGLQFVNEVVGGVVPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKATVFDGSYHDVDSNEMAFKVAASMATKQLAQKGGGELLEPIMAVEVVTPEDYMGDVMGDLNRRRGMILGMEDTVSGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFKKYNTAPSHIVETVTKKQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMA7_HUMAN
Sequence: MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAAGKGPLATGGIKKSGKK
What are the official names of this protein?
Translation machinery-associated protein 7, Coiled-coil domain-containing protein 72.
What is the protein family that this protein belongs to?
Belongs to the TMA7 family.
Protein: RL24_ROSCS
Sequence: MHVKTGDEVLIITGKDRGKRGKIKESRPKEQRVIVEGLNIVKRHMKPRGPTRPGGIIEMEAPIHVSNVMLICPKCGRASRTGHRFLEETDHKGRPKKVRYCKACDAVIDE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PSAA_SYNP2
Sequence: MAVKVDKDPVPTSFEKWGKPGHFDRTLARGPKTTTWIWNLHADAHDFDSQTSDLEDISRKIFSAHFGHLAVVFVWLSGMYFHGAKFSNYEAWLNNPTVIKPSAQVVWPVVGQGILNGDVGGGFSGIQITSGLFYLWRAAGFTNSYQLYVTAIGGLVMAALMVFAGWFHYHKAAPKLEWFQNAEAMMNHHLSVLLGCGSLGWTGHLIHVSLPVNKLLDSGVAAKDIPLPHEFFDASVMAELYPSFAQGLKPFFTLDWAAYSDFLTFKGGLNPTTGSLWLSDVAHHHLAIAVLFIIAGHMYRTGFGIGHSMKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAVNLALLGSLTIVIAHHMYSMPPYPYMATDYGTQLSLFTHHTWIGGFLIVGAGAHGAIFMVRDYDPAKNVNNLLDRVIRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMRALGRPQDMFSDSAIQLQPIFAQWIQNIHTLAPGGTAPNAIASASQVFGGDVVAIGNKVALMPITLGTADFMVHHIHAFTIHVTVLILLKGLLYSRSSRLVPDKGQLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHFSWKMQSDVWGTILPDGSVSHVTGGNFATSAITINGWLRDFLWAQSSQVINSYGSALSAYGIMFLAGHFVFAFSLMFLFSGRGYWQELIESIVWAHNKLKLAPAIQPRALSIVQGRAVGVAHYLLGGIVTTWAFFLARSLSIG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RNM5_BACCR
Sequence: MEASMKIKEIIVVEGKDDTVAIKRAVDADTIETNGSAIGDHVIEQVKLAQQKRGVIIFTDPDYPGERIRKIISDKVPGCKHAFLPKEEALAKRKKGVGIEHASNESIRRALENIHEEMEAYTGEISWSDLVDAGLVGGEMAKSRRERMGKLLKIGYTNAKQLHKRLQMFQVSKESFAEAYKQVIQEEKK
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5, RNase M5, Ribosomal RNA terminal maturase M5.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVGO
Sequence: MAARLCCQLDPARDVLCLRPVGAEPCRRPVSGSLRTLPSSLPSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARCMETTVNAPRNLPTVLHKRTLGLSAMSTTKIETYFKDCVFKDWEELGEEIRFKVFVLGGCRHKLVCAPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: KPCB_DANRE
Sequence: MAEPANSDGEERSAPMRGFARQGALRQKNVHEVKNHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKVHTYSSPTFCDHCGSLLYGLIHQGMRCDHCMMNIHKRCVANVPSLCGTDHTERRGRIQITAEIKNNVLTVSIKEAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCCLNPTWNETFTFNLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKQGVDGWFKLLSQEEGEYFNVPVPPEGEEGNEELRQKFERAKIGPSKTDGSSSNAISKFDSNGNRDRMKLSDFNFLMVLGKGSFGKVMLAERKGADELFAIKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTQLHSCFQTMDRLYFVMEYINGGDLMYHIQQVGKFKEPHAVFYAAEIAIGLFFLHSKGVIYRDLKLDNVMLDAEGHIKIADFGMCKENMLDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHHVSYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIREHGFFRYMDWEKLEHREVQPPFKPKACGRDAENFDRFFTRHPPVLTPPDQEVIMNLDQDEFEGFSFINPEFPAMEAQS
What is the function of this protein?
Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation.  Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell survival.  Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of card11/carma1, leading to activate the NF-kappa-B signaling.  Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates isoform p66Shc of shc1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer.  Acts as a coactivator of androgen receptor (andr)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation (By similarity).
What are the official names of this protein?
Protein kinase C beta type, PKC-B, PKC-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Peripheral membrane protein.