PharMolix/UniProtQA huggingface dataset:
Protein: MALD2_HUMAN
Sequence: MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS
What is the function of this protein?
Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity).  Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti (PubMed:17186462).
What are the official names of this protein?
MARVEL domain-containing protein 2, Tricellulin.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Located at tricellular contacts.
Protein: STEA_SALT1
Sequence: MPYTSVSTYARALSGNKLPHVAAGDYENKLSTKIMKGILYVLTAGLAYGFTRVIEHYCNVTPKVAEFCANAGNIHNHLADAVRDGLFTIDVELSDGRMLTFEQLSLIAEGKPIVRISDGEHTVEVEGTFEEICMRLEEGFFEAPAYYDYDIDEKYKTVRERMAAYNALPQALGAIPCLEYYIARASNMQEAKAQWAADIKARYHNYLDNY
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  Could be required for passage of bacteria from the peritoneal cavity into the spleen, for survival and replication within host cells, or for avoiding host immune response.
What are the official names of this protein?
Secreted effector protein SteA, Salmonella translocated effector A.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm. Localizes to the trans-Golgi network within both transfected and infected host epithelial cells.
Protein: Y1542_VIBC1
Sequence: MEMSNAQRLILSNQYNLMSQLDPSNAAKYKRLQTIVERGYELQMRELNKDFGCITETECREIIDIMEMYHAMQESNKMLDDEERGKVDQRRLQFLGFDIATEAQQVHYVRFLVDSEGLYPQFDKADHHFNSQMPMLDKYRRMLKTWRNCPRQYHLCANELAQIFSA
What are the official names of this protein?
UPF0304 protein VIBHAR_01542.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: HOA2_RHOJR
Sequence: MSKKITIVDTTLRDGMSSVSHQFTPQNVADIARGLDKAGVPTIEVAHGIGLGASSIQYGFAAATDPDYVRAAVDAVENADIAALYVPGIATLAELQQAIDAGIKTVRVAVHCTEADCGQQPVEWAKEHGLTVMTFLMMSHKLDPQPLAEQAAKLDSYGADVVYVVDSAGAMVPRHAGERVAALRQAITADIGFHAHNNLGVGIANALTAAENGATFIDGSLRGLGASAGNAQTEVLAAAFERAGWDTGVDLFPLIDTAEHVVAPLMKEPQIVDETALVLGYAGVYSTFFHPTKRAAKKFGVPARDILMELGRRGVIGGQEDMIIDVASELAGRTYETPAPAGV
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RL33_CLOAB
Sequence: MRVKLTLACTECRQRNYNTMKNKKNDPDRLEMKKYCPFCHKHTLHKETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS8_PSESM
Sequence: MSMQDPLADMLTRIRNAQMAEKPVVSMPSSTLKVAVAKVLKDEGYIAGYQISSEVKSSLSIELKYFEGRPVIEEVKRVSRPGLRQYKSSDDLPKVRGGLGVSIVSTSKGVMTDRAARAAGVGGEVLCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL23_MARSD
Sequence: MDYTQILIKPVISEKATDIKEAANQVAFYVLPSANKTEVKKAVESAFDVKVDSVRIVRKRPGLRRKFGRVVGKLSGYKKAYVKLSEGEKIEFFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SYE_SULAC
Sequence: MSDDIRNLVYKYALHNAYTHNGKANVNAVVSKIFAERPELRSKAKDIVEIAKELVNYVNSLDVESQKKELESKFPEMLEEKKREKESKKELPDIPVSGVLVTRFAPNPDGPLHLGNARAAIISHEYARIYNGKFILRFDDTDPKTKKPIPEAYDWIKEDLKWLGIKWDLEVRASARLETYYNFARILLSKGYAYIDLCKEAEFKERRSKREACPHRETSPESNLELFEKMIHGEFEEGKAVVRLKTDLKLPDPSQRDWVLLRVINVKKSPHPIEGDKYWVWPTYNFASAIDDYDLGVTHIFRGKEHAVNAEKQKWIYNYMGWKYPYVREFGRLKLEGFMMSKSKIRTVVEKGVGIDDPRLPTLAGLRRRGILSDTIKEIIITVGLKETDATISFDNLASTNRKKLDKIAKRLMFVGSPKEFIIDIPQPILAKIPYHPSNPNEYREISVNPGDIILINENDAKDKVLRLMELCNVTVNGDKLVYNSKGIEDAKKLGMKIIQWVKKDESVPVVVLSPDPEKGIETINGVGESEIRNLNKGEIVQFIRYGFVKVDEKSADGQVTVIFSHE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYOBP_PIG
Sequence: MGRLGPSNGLLPLLLAVGGFSLVQAQRECSCSAVSPGILAGIVLGDLVLTLLIALAVYSLGRLVPRTRGAVDVTRKQHIAETESAYQELQGQRSDVYSDLNTQRQYYK
What is the function of this protein?
Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity).  TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity).  Also has an inhibitory role in some cells (By similarity).  Non-covalently associates with activating receptors of the CD300 family to mediate cell activation (By similarity).  Also mediates cell activation through association with activating receptors of the CD200R family (By similarity).  Required for neutrophil activation mediated by integrin (By similarity).  Required for the activation of myeloid cells mediated by the CLEC5A/MDL1 receptor (By similarity).  Associates with natural killer (NK) cell receptors such as the KLRD1/KLRC2 heterodimer to mediate NK cell activation (By similarity).  Associates with TREM1 to mediate activation of neutrophils and monocytes (By similarity).  Associates with TREM2 on monocyte-derived dendritic cells to mediate up-regulation of chemokine receptor CCR7 and dendritic cell maturation and survival (By similarity).  Association with TREM2 mediates cytokine-induced formation of multinucleated giant cells which are formed by the fusion of macrophages (By similarity).  Stabilizes the TREM2 C-terminal fragment (TREM2-CTF) produced by TREM2 ectodomain shedding which suppresses the release of pro-inflammatory cytokines (By similarity).  In microglia, required with TREM2 for phagocytosis of apoptotic neurons (By similarity).  Required with ITGAM/CD11B in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).  Promotes pro-inflammatory responses in microglia following nerve injury which accelerates degeneration of injured neurons (By similarity).  Positively regulates the expression of the IRAK3/IRAK-M kinase and IL10 production by liver dendritic cells and inhibits their T cell allosimulatory ability (By similarity).  Negatively regulates B cell proliferation (By similarity).  Required for CSF1-mediated osteoclast cytoskeletal organization (By similarity).  Positively regulates multinucleation during osteoclast development (By similarity).
What are the official names of this protein?
TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12.
What is the protein family that this protein belongs to?
Belongs to the TYROBP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SEELE_DROME
Sequence: MLTKALILFGLLALAQGYSFTSREVKCHVCKAVVTELEEAIAKEDPHKMADVSGFRLDAQGNSISKKVRLVKSEMFLTELMEKICEKMDDYLKATYKSNGKFTLLKMIINGQMNPDSSLVDFVQDGDLNKSLGHFCNEVLEDNDEIFVKAFQAEELGNDLDIKICSEQASYCDESPVQEEYDFDGKEEL
What is the function of this protein?
Involved in embryonic dorsal-ventral patterning which is generated by a series of serine protease processing events where gd processes snk which cleaves ea which then processes spz into the activating ligand for the Toll receptor.  Required during this process for the secretion of ea from the developing embryo into the perivitelline space and for ea processing.
What are the official names of this protein?
Protein seele.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: Y1225_BACCR
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFEAQDEQLESIVNELHTIASKTNPFTLHVGKVGSFAPVNNVLYFKVEKTPELTFLNEEMHSGLFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BC_1225.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: Y1981_DESVH
Sequence: MPSFDVVNKIELQELDNAVNNVKKEIETRYDFRNTTTEIDLHKGDLRITVVAADEMKMRALEEMLHAHCVRRKIDPRCLEFKEIEATSRGAVKREVQVKEGIAKDVAQKIVKAIKDSKLKVQGAIQDQQVRVTGKKIDDLQDVIALLREGDFGIPLQFVNMKN
What are the official names of this protein?
UPF0234 protein DVU_1981.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: MTR4_YEAST
Sequence: MDSTDLFDVFEETPVELPTDSNGEKNADTNVGDTPDHTQDKKHGLEEEKEEHEENNSENKKIKSNKSKTEDKNKKVVVPVLADSFEQEASREVDASKGLTNSETLQVEQDGKVRLSHQVRHQVALPPNYDYTPIAEHKRVNEARTYPFTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLGYNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRINKRNPSAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFPDGIPVLDPVKNMKIEDEDFLKLMKKIDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAVLKLIHRDIVSAGSLYL
What is the function of this protein?
ATP-dependent RNA helicase required for the 3'-end formation of 5. 8S RNA.  Cofactor for the exosome complex that unwinds secondary structure in pre-rRNA.  Required for nucleocytoplasmic transport of mRNA.  May serve as a chaperone which translocates or normalizes the structure of mRNAs in preparation for export.  Component of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information.  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates.
What are the official names of this protein?
ATP-dependent RNA helicase DOB1, mRNA transport regulator MTR4.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LTP2_THECD
Sequence: MSVLPGAAAIAGIGATEFSKNSGRSELQLACEAVLAAIADAGLEPSDVDGLVTFTADTSSEIHVARNTGIGELKFFSRVGYGGGAACGTVQQAAMAVATGIAEVVVCYRAFNERSGVRYGLGQAGRQMDQGADSAAYAWLLPFGLNTPAQWVAMFARRYMHEYGATSEDFGRVAVVDRKHAATNPKAWFYQRPITLEDHQNSRWIVEPLHLLDCCQESDGGQALVVVSTERARDLPHPPALIWGAAQGSGYDQHMMTSYYRSEITGIPEMGLVGQQLYAQSGLNPSDIGAAILYDHFTPLVLPQLEELGFCARGEAKDFIADGNLEIGGRLPCNTHGGQLGEAYIHGMNGIAEAVRLVRGTSVNQPGDVTNVLVTAGTGVPTSGLILGADR
What is the function of this protein?
Probably involved in bile acid degradation (Probable).  In vitro, when associated with the ChsH1/ChsH2 hydratase, catalyzes the retroaldol cleavage of 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA (17-HOPC-CoA), forming androst-4-ene-3,17-dione and propionyl-CoA (PubMed:31209106).  The in vivo substrate is probably a closely analogous bile acid degradation metabolite (Probable).
What are the official names of this protein?
Steroid side-chain-cleaving aldolase, 3-oxo-23,24-bisnorchol-4-en-17-ol-22-oyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily.
Protein: RL10_LEGPL
Sequence: MTLNLAAKKAVVEEVTAVASKAISAVVADYRGLTVNQMTQLRSEARKSGVYLRVVRNTLTRRAFKNTEFECLNDLLVGPVFIALSLEAPSDAARLLKDYAKTFEKLEIRALSVGGKVYNANQIDAVASLPTRDEAISKLMYVMKAPIEKFVRTLAEPHAKLARTLAAVKDKKAGNPA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: UPP_CLOPS
Sequence: MSKVTEITHPLILHKLAFIRDKNTGSKDFRELVSEVSMLMAYEVTRNLPMEEIEIETPVCKTKCKVLAGKKVAIVPILRAGLGMVDGMLQLIPAAKVGHIGLYRDEETLQPVEYFCKLPQDIAERDIIVVDPMLATGGSATDAITLLKKRGAKQIRLMCLISSPEGIEFVQKAHPDVDIYVACIDEKLNDHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MATK_TRIGN
Sequence: MEELQLQGYLEKDGSRQQNFLYPLIFQEYIYTLAHDHGLNSSIFDEPMEIVGLGYDNKSSSVLVKRLITRMYQQNSLIYSMNDFNQNRFVGHNNSFYSNFDSKMVSEGFAVIVEIPFSLRLVPSSEEIPKSQNLRSIHSIFPFLEDKLSYLNYVLDILIPYPIHLEILVQILQCWIQDVPSLHFLRLFLHEFHNWNNLITPTKSISVFSKENKRLFRILYNSYVSEYEFVFVFLRKQSYYLRSTSSRAFLERTHFYVKIEHLIDVCHNHFQKILWFFKDSFMHYVRYKGKAILASRGTYLLIKKWKCYLVNFWQYHFHFWSKPYRIHINPFSNYSFYFLGYISSVRINPSAVKNQMLENFYLVDTLTQKFDTIVPVIPLIGSLSKAKFCTILGHPISKPIWAELSDSDIIDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRNLLQRLGSGLLEEFFTEEEQVISPIFPKTTLFPLHGSHKERIWYLNIIRINDLANYLDWS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYFB_LISIN
Sequence: MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDAEKLNKCLVQTDEEEPVQIICGAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMICSLAELGFESKVVPKAYADGIYVLPEHVETGVSAITLLGLDDAILDMAITPNRADALSMNGVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPTETPYYAIKMVENIEIKESPLWLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKDQEEITTLDGEKRILQTGHTVITNGTEPIAIAGVMGGEFSEVTETTTTVALEGAIFSSSSVGKASRELYLRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLVGGVVEVDNREKAVNKIETSLTRINRILGTEISLSEIETIFDRLGFVLEVKEDTLIIEVPTRRWDITIEADILEEVARIYGYDEIPVTLPATSTTGGLSDSQKARRVMRAYLEGAGLNQALTYSLTSKKDATRLALSDEKTVALSMPMSEEHSHLRTSIVPQLIRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLAGLITGNWHTADWQKTPKPVDFFVLKGIVEGLVNKLGIEAELHWKQIEKEELHPGRTASIQLEGKEIGYLGALHPAVEASYDLKETYVFEINVKALLDATKEKVVYHPIPRYPEMTRDLALLVDKDTDHATISQVIKEHGGNLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEEDVQKATNKVVEALQAKLHAIIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PARMW
Sequence: MTFTIRHDWTIAEIQALLELPLMELLWQAQYVHRAANPGYRVQLASLLSVKTGGCEEDCAYCSQSIHNSSDVTAFEAQMQVEPVLQRARAAKEAGADRFCMGWAWREIRDGAPFEAMLSMVRGVRDLGMEACVTAGMLSDQQAERLAEAGLTAYNHNLDTSPEHYDRIISTRTYQERLETLQRVRKAGVTLCCGGIIGMGETLRDRASMLQVLASMAPHPESVPVNGLVAVEGTPLEDQAPFEPLELVRMVATARILMPRARVRLSAGRESMSREAQILCLQAGADSIFYGDTLLTTGNPDVEADRQLLADAGVQANWQECQTTA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YR846_MIMIV
Sequence: MDNTYYQLPLELWVKIVDYTDEIYLLLTNKSFFELLYLVNVKMDTIKYVVENNLSDVLKHIVELKNINHPIFDKDIITLESLNKYLKKSCKYGLIEIVKYLIILGANIKERDNIAVGKACENGHLEMVKYLVSQGADITVDNNYSIMKASSNGHFEMVQYLINEGADITA
What are the official names of this protein?
Putative ankyrin repeat protein R846.
Protein: MNMG_ALKEH
Sequence: MDHPERFDVIVVGGGHAGTEAAMAAARIGARTLLLTHSIETVGQMSCNPAIGGIGKGHLVREIDALGGIMARAADRGGIQFRTLNSRKGPAVRATRAQADRQLYRQAIRRAVENQPRLALFQQSVDDLIVEGGRVTGVVTGMGLRFRAPAVVLTVGTFLGGRIHIGESNYGGGRAGDPAANALAARLRELPFQVDRLKTGTPPRLDGRTIDWARLTEQPGDDPAPVFSFLGRPDEHPAQVPCHIAHTRPETHDIIRGALDRSPMYSGTIEGVGPRYCPSIEDKVVRFADKGSHQIFLEPEGLDTHEVYPNGISTSLPFDVQYELVRSIPGLEQARIVRPGYAIEYDFFDPRGLHPTLETRHLEGLWFAGQINGTTGYEEAAAQGLLAGLNAALRVQGREPWYPRRDQAYLGVLVDDLITRGTREPYRMFTSRAEYRLMLREDNADLRLTPIGRDLGLVDDERWRRFNAKREALEREQARLAATLIRPGDLPDALARQVLGGPLRKEQRLEELLRRPDVGYADLMRLPGAGDPVPDAEVVEQLEIQARYAGYLERQHDEVARARRHEQLPLPEGLAYDRVAGLSSEVREKLAAHRPATVGQAARIPGVTPAAVSLLLVHLRRQGLLRESA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAF8_HUMAN
Sequence: MVMRPLWSLLLWEALLPITVTGAQVLSKVGGSVLLVAARPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRAQLHSNLSLELGPLESGDSGNFSVLMVDTRGQPWTQTLQLKVYDAVPRPVVQVFIAVERDAQPSKTCQVFLSCWAPNISEITYSWRRETTMDFGMEPHSLFTDGQVLSISLGPGDRDVAYSCIVSNPVSWDLATVTPWDSCHHEAAPGKASYKDVLLVVVPVSLLLMLVTLFSAWHWCPCSGKKKKDVHADRVGPETENPLVQDLP
What is the function of this protein?
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
What are the official names of this protein?
SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TDCC_SHIFL
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTLSMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_RHIME
Sequence: MSATNKQNAASVFGRPWIFIRGVPSMKFLPPEGPTEIAFAGRSNVGKSSLINALVGHKGLARTSNTPGRTQELNYFVPDGYSGEAGDLPPMALVDMPGYGYAQAPKEQVDAWTKLVFDYLRGRSTLKRVYVLIDARHGIKKNDEDVLALLDKAAVSYQIVLTKTDKIKAAGVPRLVAETLEKIKKRPAAFPEVLSTSSEKGEGIEDLRAAIELAVTR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PAHO_DIDVI
Sequence: APQEPVYPGDDATPEQMAKYAAELRRYINRLTRPRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC1_PROMT
Sequence: MTNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLKYKQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIATSASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVHVPLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQSKQPKFGDYSNTYASLEDVLQALEDKRIDLHDWVWVRFSGEIEDDDELQNPLKSETLKDGTRIEEWTYRRDRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: RS8_BRUA2
Sequence: MSVSDPLGDMLTRIRNAVGRKKTKVSTPASKLRARVLDVLQAEGYIRAYTQSEFENGKAEIEIELKYYEGVPVIREITRVSKPGRRVYVSVKSIPQVANGLGISILSTPKGVMADHEAREQNVGGELLCRIF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ZAPD_BURO0
Sequence: MILYEYPFNERIRTLLRLEDLFERFAFFLAQEDPREHHVALTTLFEIAEVTGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLVDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRQDIAKWILPMLPLRDAAAIVLRLARESGQASKVMAMQGSYQQMLSGRSYQLMQVRVPPELRVIPEASANKYMLWVRFTMQDGDVRPRAVDIDVPFHLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.