PharMolix/UniProtQA huggingface dataset:
Protein: ZNG1B_HUMAN
Sequence: MLPAVGSADEEEDPAEEDCPELVPMETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNEFGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKKGKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLAEEKPDGLINEATRQVALADAILINKTDLVPEEDVKKLRATIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLLGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT
What is the function of this protein?
Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them.  Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation.  Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1.  After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1B to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis.  GTP/GDP exchange is required for release of active METAP1.
What are the official names of this protein?
Zinc-regulated GTPase metalloprotein activator 1B, Cobalamin synthase W domain-containing protein 2, COBW domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Protein: LONM_CAEEL
Sequence: MYRAGAVLLRGATRTRLLAAASAHQSFATFSQRNQSILMMKSMELAGNSGERRFYSTHDDPIAVDDSLELYKDLGGMSPIQVPADMPNVPMLAINRYPLFPGFIKKVDIVKDDNLKALIRRQLSLKQPYAGVFVKRDDENKEETITSLSEVYPTGSFVQIIEVRDQGSVLELVLSAHRRIRALEPIDEITPKNETPLNGRRARGKRAASATSPLTPPPSPPPLAPSVASVAPEISATEEKEEKTTPPSATGEKQKKGIIMVRTENVVAEPVPKNNETKATMMAIVQTIRDVVQFNQLFGQQINLLLHPSQNVIDNPVYLCDLVATLVQSAETKDLQEMMDEIDVSKRLKIALLLIQKEKAVAKLKYDINKDVEKKVQDHHRKYLLNEQLKVIKKELGIEKDEKTTIIEKIDERIKTLAVPEYALKVINEEKTKLQFLDPHSSEFSVTRNYLEWLTSVPWGLTSPENRRLSVAKKALDEGHYGMKDVKERIMEFIAVNLLRKSIGGKILCFHGPPGVGKTSIAKSIATALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKMIQCMKKVKTENPLVLIDEVDKIGGAGFHGDPASALLELLDPEQNANFNDHFLDVPVDLSRVLFICTANEISKIPGPLRDRMEMIDVSGYLAEEKVEIAHQHLIPQLRKDTSLATEQLKIEDSALEELIKHYCRESGVRNLQQHIERIFRKAALQIAEQQNEDEEPAEKATTAITENSEAEPITSTSSADCLKSSAEQIVVCTENLQKFVGRPKFTSDRMYEVTPPGVIMGLAWTAMGGSALYIETVLKRPVDLTNDKDGSIETTGNLGDVMKESVRTALTVAKGILAREQPDNKFFDKAHIHIHVPEGATPKDGPSAGVTLVSSLLSLALDRPVVQDMAMTGEISLTGKVLPVGGIREKVIAARRVGAKRVFLPNENRRDFDDLPEFMKSELDIRFVSHYDELYEHLFQ
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.  Involved in the degradation of transcription factor atfs-1 in the mitochondrion (PubMed:22700657).
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NUDC_PSEPK
Sequence: MSARWTTAVLDPQMTGGLAVARSPEGFLVDANGALFPRDWLKRQDLDVLCEHGIGHFDGQPVFLLELRSATDVPGCSWRGLRAFMLEGDFDTYKVLGYAAQIGTWAREHRFCGSCGQPMTQIRWERAMYCQPCDLRSYPRISPSMIVLVTRGDEILLARSPRFVTGVYSTLAGFAEPGESAEDCLVREVREEVAVEVKNIQYVGSQCWPFPHSMMLGFHAEYAGGEIVMQPDEIEDAKWFSVHDLPPLPAGRSIARYLIDLYVARRLGCDIPAFPS
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: RL6_BART1
Sequence: MSRIGKRPISIPSGVTATVEGQLVKAKGPKGELSYVVNDEVLVKFEENVISVMPRDQSKDARSKWGMSRSMIENIFCGVKDGFEKRLEINGVGYRAALQGKDIQLSLGFSHDVVYKVPSGVTVTVPKPTEIVISGIDKQQVGQVAAEIREYRRPEPYKGKGVKHADERIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RPOB_SHEPW
Sequence: MVYSYSEKKRIRKDFGKRQKVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGITYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKQDSLVMDLVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQDYIDPDTGEVLVSANAEIGLEDLAKLSLAGIKEVSTLYINELDNGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSKVGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIIAIRNGLDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVVTDEVDYLSAIEEGRYVIAQAIVELDENNRMMDELIACRHKGDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAKRGGYVDYVDASRIVVKVDEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVDKDKRAVEIEEMHIAQAKKDLTEEFQILEDGVLGRARNLLLGAGFDEAQLDAIPRSQLLMQTIDDEAKQTELEQLAEQAEELKADFDKKFEVKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNRITEMLEEQRELAELRGYIKEVYELGDEVQQRVDIDSFTDDEVLRLAKNLKGGVPTATPAFDGAKEKEIKQMLALAGLPTSGQLTLCDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MFAP3_HUMAN
Sequence: MKLHCCLFTLVASIIVPAAFVLEDVDFDQMVSLEANRSSYNASFPSSFELSASSHSDDDVIIAKEGTSVSIECLLTASHYEDVHWHNSKGQQLDGRSRGGKWLVSDNFLNITNVAFDDRGLYTCFVTSPIRASYSVTLRVIFTSGDMSVYYMIVCLIAFTITLILNVTRLCMMSSHLRKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLILNCRAFVEEMFEAVRVDDPDDLGERIKERPALNAQGGIYVINPEMGRSNSPGGDSDDGSLNEQGQEIAVQVSVHLQSETKSIDTESQGSSHFSPPDDIGSAESNCNYKDGAYENCQL
What is the function of this protein?
Component of the elastin-associated microfibrils.
What are the official names of this protein?
Microfibril-associated glycoprotein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FB176_ARATH
Sequence: MASCERSLLPIDIIEEICCRIPVEYLTQFKLTCKQWFALLKDKRFIYKYLDLFQEQERFIRIDRIVQIIDPVKGARSSSPIPQEFDNVAQISTMVHCDGLLLCRCKNERSRSYKLAVWNPFLSRVKWIEPMDFYSSNDFYGFGYDNVCRDEYKLLRIFDGEIEDESEIAGSYEPKIQIYDFKSDSWRIVDDTRLDWSIDPPCKGVSVKGNMYWIAHWNNRPEIFIQSFDFSTETFKIVCNLPFECNVLDTAALSSLRGDRLSLLHQSGETMKIEVWITNKLSDEVVSWTKYVDVTSPDLPTLHTDQHLTHPSYFIDKNDNIMVWCEQETEEETDDDVCVSVCMISKDGIVKKQIDAGRCDLCSDNRPFVCGYAYVPSLVPVPE
What are the official names of this protein?
Putative F-box protein At3g22650.
Protein: DCDB_MICLC
Sequence: MLLSDRDIRAELDSGRVGLDPLDPTMVQPASVDVRLDRFFRLFDNHRYAHIDPRQEQDELTRLVEVDPDEAFILHPGEFVLGSTYEQVTLPDDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPITLWPGMKIGQLCFFRLSSSAQSPYGTGANQNRYQGQRGPTASRAHRDFHLTRIER
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CEL7B_MAGO7
Sequence: MAKFSALCSLALLGLATAQKPVGTETHEKLTTFRCTVAGGCVEKTNYIVLDSITGHRIYQPAAETLDCGARGAAPNVTACPTKEACAENCAMEGRTDYGSQGVSTDGASLRLQILHDGKKVAPRVYLLDETEAKYEMLRLTGNEFAFEVTMDKLPCGMNSALYLSEMEEDGGKSELNPGGAPWGTGYCDAQCYVTPFINGEGNIKGNGACCAEMDIWEANSRATHIAPHPCSKPGLYLCEGDECGSTGVCDKSGCAWNPNRIAQPHYYGNNDTFKVDTLKPMTVVTQFPTDASGKLAAIRRLYVQGGVVIKAETVHKAGLPEVDALTDPFCEAFGSQRYMALGATGGMGDALARGMVLVMSIWWDETGGNMQWLDGIASGSGPCNATEGAPANIPLVEPNPEVTFSNLKWGEIGSTFQGGARRL
What is the function of this protein?
Endoglucanase that is involved in the biological conversion of cellulose to glucose.  Hydrolyses internal beta-1,4-glucosidic bonds.
What are the official names of this protein?
Endoglucanase 1, Cellulase 1, Endo-1,4-beta-glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS_RICRO
Sequence: MLLNMNLQELKQKYNYDVATKMMQQYLDIKFAHLDCLLLFRMGDFYEMFYEDAILASNVLGIALTKRGKNGEEEIAMCGVPYHALENYLTKLIEENYKVAICDQLETPEEAKNRGGYKAVVTRDVTRIITPGTIIEENLIASAEPNYLASLVIPKNKETASLCYVDLSTSEIVVVNVPETEILNELARLKPREILLSENLRSSNLADSIFKQLNFRITYQVDSFFAINKCKKIILDFYKMKDIKGIGEISSSQICAIGSVLEYLSLTQKQNIPHLPIPRIINFHSYMTIDFSTRRNLEIVTNSQGDSQGSLLSTLNHTVTKQGGRLLYNFLSSPLTNIAKINHRLNITEFFYSNLEIVKKIRELLKKTSDIERCLTRITMNRSSGRDLLSIKYTLETATIIKEVFFDAYGFNLPDFIEKIIKPLSGDAELYNLIDETIREDAPNNLNDGGIIKHEYHPKVAQLHDLINNGKLYIEKLKDQYRKETGIDSLKISHNNVIGLFIDITAKNVNKILDPKFIHRQTTVNHVRYTTAELQKLESELVNAKTLVISLEKELYADICSQVIEKASYLRMLASSLSGLDVFCNFAYIADEYDYVKPEFTDDLSFDIVKGRHPVVEKALQRESKSFVYNDCHLSELERIWLITGPNMAGKSTFLRQNAIIAIIAQIGSFVPAKSAKIGVVDKIFSRIGAADDLIKGQSTFMAEMLETSAILAQSTKNSLIILDEVGRGTSTYDGVSIAWSVLEYIHDKLKCRCLFATHYHELTVMSNFLPALQNYTIAIEESGKDILFLHNIISGAADRSYGLHVAALAGLPESVINRAEQILLKFEKTSTGKGKNILSTESNNLSLFYLEPNKTTISSKLDKKFSTIDPDKLSPKEALELIYELKKLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SSU72_BOVIN
Sequence: MPSSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVINVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRTFLHTVCFY
What is the function of this protein?
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II.  Plays a role in RNA processing and termination.  Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK (By similarity).
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72, CTD phosphatase SSU72.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly in the cytosol.
Protein: CARA_BART1
Sequence: MIQTISSSRPWSVNTPTALLVLADGTVIEGKGAGATGIAEAELCFNTAITGYEEILTDPSYTQQIVNFTFPHIGNVGANSEDIESLTPLSCHGAVGAIFKADITHPSNYRASENLHQWLKARKIIALCGIDTRALTILIREKGTQNAVIAHNSDGNFDIPSLKKRAQKWHGLVNLDLTEEVTSPSSIEWDEEPWCWNKGYGTNNVHNLHIVAIDYGIKRNILRLMATQKARITVVPAHTTAKEILAMTPDGVFLSNGPGDPAATAQYAIPTINTLIDHNLPIFGICLGHQLLALAVGAKTVKMHQGHHGANHPVKDLNSGKVEIVSMNHGFAVDAATLPKHVQETHISLFDGSNCGIRIIGKPVFSVQYHPEASPGPQDSHYLFQHFCDLIMNHKKIS
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: AROA_ECOHS
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTGLGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAG_PECAS
Sequence: MTAQSPYLSFHGIGKEFPGVKALSDISFSCHAGQIHALMGENGAGKSTLLKILSGNYSPSAGEIHIQGKPVQFSNTMDALNAGVAIIYQELHLVPEMTVAENIYLGQLPHKYGMVNYSLLRYEAKLQLQHLGLDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIEQLFRVITELRSEGRIILYVSHRMEEIFALSDAITVFKDGRYVCTFDDMQQVNHESLVQAMVGRNLGNIYGYAPRPHGEDRLTLKDVKAPGVKSTISLNVKQGEIVGLFGLVGAGRSELMKGLFGATKITSGQVLLDGKPLVVNSPIDAIRQGVMLCPEDRKADGIIPVHSVRDNINISARRKSLKAGFIINNQWEADNAAQRIDALNIKTPSDEQLIMNLSGGNQQKVILGRWLSEEMKVILLDEPTRGIDVGAKHEIYHVIYELANQGIAVLFASSDLPEVLGLADRIIVMREGAVSGELLHADATEQKVLSLAMLRIPDIESAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CS2LB_RAT
Sequence: MKFIILTCLLAVALAKQESKDNSQEDFKQTVDVVIFPGQETVKNIPIPQMESVEAPIKNKCYQSIQTFKPPQALKGLYQYHMAKNPWGYTVNRAFPSTRTLQYNQKTMDLSMRAREKIVMSEIKKNIQDYVTKMKQYSKITWPRFVKSLQQYQKTMNPWSCYPYTLLQV
What is the function of this protein?
Important role in the capacity of milk to transport calcium phosphate.
What are the official names of this protein?
Alpha-S2-casein-like B, Casein alpha S2-like B, Delta-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_ECO27
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLDCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYDAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RMLD_STRGR
Sequence: MSPYPRPRWLVTGASGMLGRELTPLLDRRGAAVTALGRGHLDITDGAAVRSAVAEHRPAVVVNCAAWTAVDEAESEPALAMAVNGEGPRHLAQACRAVGAVLLQLSTDYVFPGSGGRPYREDHPTGPRTVYGCTKRAGERAVLEVLPDTGYIVRTAWLYGAGGPNFVAKMIRLEADEDTVLVVDDQHGQPTWTADLADRLAALGAAALAGTAPAGIYHATNTGGTTWNALAPETFRLLGADPARVRPTTSLALARPAVRPRYSVLDQSRWKAAGLEPLRHWRAALTESFPALCGRAGRPVPGPR
What is the function of this protein?
Involved in the biosynthesis of the streptose moiety of streptomycin (PubMed:1661369).  Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose (By similarity).  RmlD uses NADH and NADPH nearly equally well (By similarity).
What are the official names of this protein?
dTDP-4-dehydrorhamnose reductase, dTDP-4-keto-L-rhamnose reductase, dTDP-6-deoxy-L-lyxo-4-hexulose reductase, dTDP-6-deoxy-L-mannose dehydrogenase, dTDP-L-rhamnose synthase.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family.
Protein: ATPA1_VIBC1
Sequence: MQLNSTEISDLIKQRIESFDVVSEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGRYALALNLERDSVGAVVMGPYANLKEGMKVTGTGRILEVPVGPELLGRVVNTLGEPIDGKGPIEAKLTSPVEVIAPGVIARKSVDQPVQTGYKSVDSMIPIGRGQRELVIGDRQTGKTAMAIDAIINQKDSGIFSIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFNAGVRPAVDPGISVSRVGGSAQTKIIKKLSGGIRTALAQYRELAAFAQFSSDLDEATKKQLDHGQKVTELMKQKQYAPMSVFDQALVIFAAERGYLADVELNKLLDFEAALLSYARGQYAEFAAEIDKTGAYNDEVEAQLKKLTDDFVATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DGKD_HUMAN
Sequence: MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA
What is the function of this protein?
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12200442, PubMed:23949095).  Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable).  By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development (By similarity).  May also regulate clathrin-dependent endocytosis (PubMed:17880279).
What are the official names of this protein?
Diacylglycerol kinase delta, DAG kinase delta, 130 kDa diacylglycerol kinase, Diglyceride kinase delta, DGK-delta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Isoform 1 translocation from cytoplasm to the plasma membrane is induced by phorbol esters (PubMed:12200442). Phorbol esters induce the conversion into the monomeric form which can translocate to the plasma membrane (PubMed:12084710).
Protein: RS4_RHORT
Sequence: MGKRLNSKHKIDRRLGVNLWGRPKSPINKREYGPGEHGQRRRKPSDFGIQLMAKQKLKGYYGNISEKAFRKYYEEASSRRGDTSENLISILETRLDAVVYRMKIVPTVFSSRQIINHGHILVNGRRVSVASYRVQEGDVIEVKEKSRQMPLILEALQSHERDIPEYITMDLAHAKGTFLRAPKLEDVPYPVQMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YCF51_CYAPA
Sequence: MIEFSLLTKITLSFTILFLILSIISIIKGWKNRFQFIGVTSFSALLTISFFVFTFVPFTHKLIPGAEKYKVVFDDGANQIVIAVSSKLNQDQLVATLEQAASDLFSPGRLSRNNNSFIIKARALSDSIGTTNNSLYLGELDKILDSNTNDFETKIKIFNDSTL
What are the official names of this protein?
Uncharacterized protein ycf51, ORF163.
What is the protein family that this protein belongs to?
Belongs to the ycf51 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: MDH_AERPE
Sequence: MITILGAGKVGMATAVMLMMRGYDDLLLIARTPGKPQGEALDLAHAAAELGVDIRISGSNSYEDMRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIVVITTNPVDAMTYVMYKKTGFPRERVIGFSGILDSARMAYYISQKLGVSFKSVNAIVLGMHGQKMFPVPRLSSVGGVPLEHLMSKEEIEEVVSETVNAGAKITELRGYSSNYGPAAGLVLTVEAIKRDSKRIYPYSLYLQGEYGYNDIVAEVPAVIGKSGIERIIELPLTEDEKRKFDEAVQAVKKLVETLPPQLRE
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.  Can also oxidize tartrate.  Can utilize both NAD and NADP.  Catalytic efficiency for malate oxidation is 3-fold higher with NADP.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: RHMD_POLSJ
Sequence: MNNMPTIKHVRAFTVRGGGADYHDQGSGHWIDDHISTPMGRYPEYRQSRQSFGINVLGTLVVEIEASDGTVGFSVTTGGELGCWIVEKHLARFIEGAKVTDIEKIWDQMFNATLYYGRKGIVLNTISGVDLALWDLLAKVRKEPVHALLGGPVRDELTFYATGARPDLAKKMGFIGGKLPLHHGPAEREEGLKKNLELLGEMRQRVGDDFWLMYDCWMSLDVEYATRLANAASEYKLKWIEEALPPDDYWGYAELRRNVPRGMLVTTGEHEATRWGFRMLLEMECCDILQPDVGWCGGITELLKISALADAHGKLVVPHGSSVYSYHFVITRHNSPFSEFLMMAPKADEVVPMFNPMLLDEPVPVNGRMKASALDAPGFGVRLNPECALQRPFPR
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: GYRB_ACIJO
Sequence: DNSYKVSGGLHGVGVSVVNALSRKLELTIHRAGHIHQQEYKHGDPVYPLTVVGDTDTTGTTVRFWPSAETFSQTIFNVDILARRLRELSFLNAGVRIVLRDERIHAEHVFDYEGGLSEFVKYINQGKTHLNDIFHFTVQAENGIGVEVALQWNDTYQENVRCFTNNIPQKDGGTHLAGFRAALTRGLNSYMENENLLKKEKVAVSGDDAREGLTAIVSVKVPDPKFSSQTKEKLVSSEVKPAVEQAMNKSFSEYLLENPQAAKSIAGKIIDAARARDAARKAREMTRRKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKIII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.