PharMolix/UniProtQA huggingface dataset:
Protein: ANP9_ZOAAM
Sequence: SQSVVATQLIPMNTALTPAMMEGKVTNPIGIPFAEMSQIVGKQVNRIVAKGQTLMPNMVKTYAA
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein SP3(HPLC 9), ISP SP3(HPLC 9), Antifreeze protein SP3(HPLC 9).
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: TPFY_AGADC
Sequence: MNFLKKSLFLVLFLGFVSISFCDEEKRQDDDEGNEREEKKEIQEDGNQEERRDKPPAWVPGK
What is the function of this protein?
Myoactive.  Has selective relaxing activity on vascular smooth muscle.
What are the official names of this protein?
Tryptophyllin-1, PdT-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_NITMU
Sequence: MPSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMNPVIVHGGGPQINDMLKRVGKQGAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGRAVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGIDPALIELLETRDFIPVIAPVGVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIADGTISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y962_CHLTR
Sequence: MWLLLVCVVVGGFYTAWNIGANDVANAVGPSVGAGALTLKQAVLIAAVFEFLGAVLLGDRVIGTIESGLVAPSGHVLSSQDYVFGMTAALLATGVWLQIASFCGWPVSTTHAIVGAVLGFGIILKEDAVIYWNSCGRVFVSWLASPIIGGYFAFLIFSFIRKAILYKKDPVSAMVRIAPFLSAIIIFALGLVLILSGAVAPVISFSPALRIVCGLSLFAFFFTIWGIRFFKLAILPQEVLPGTLLDRLLSKSTDYGRKYLIVERIFAYLQMIIACFMSFAHGSNDVANAIAPVAGIYRTLYPQSYSSKVLLVFMSLGGLGLVCGLATWGWRVIDTIGKKITELTPSRGFSVGMSSAITIAAASSLGFPISTTHVVVGSVLGIGFARGLRAINLRIIKDIVLSWFITVPAGAALSIVFFLLLRALFC
What is the function of this protein?
Potential transporter for phosphate.
What are the official names of this protein?
Putative phosphate permease CT_962.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1497_MYCBO
Sequence: MTAPGLTAAVEGIAHNKGELFASFDVDAFEVPHGRDEIWRFTPLRRLRGLHDGSARATGSATITVSERPGVYTQTVRRGDPRLGEGGVPTDRVAAQAFSSFNSATLVTVERDTQVVEPVGITVTGPGEGAVAYGHLQVRIEELGEAVVVIDHRGGGTYADNVEFVVDDAARLTAVWIADWADDTVHLSAHHARIGKDAVLRHVTVMLGGDVVRMSAGVRFCGAGGDAELLGLYFADDGQHLESRLLVDHAHPDCKSNVLYKGALQGDPASSLPDAHTVWVGDVLIRAQATGTDTFEVNRNLVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLRSRGIPEAQARRLVVRGFFGEIIAKIAVPEVRERLTAAIEHELEITESTEKTTVS
What are the official names of this protein?
UPF0051 protein Mb1497.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: RL22_DELAS
Sequence: MSETRAVLRGVRLSVDKGRLVADLIRGKKVDQALNILTFTQKKAAVIIKKVLESAIANAEHNDGADIDELKVKTIFVEQGTTLKRFTARAKGRGNRISKPTCHVYVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RUVA_ACIC5
Sequence: MIAHLRGTLLSKQPGQAIVECAGVGYDVAISVPTFTALPAEGAEVRLHIHTQVSEDAIALFGFLDREEKRLFERLITVSGVGPKLAIKMLSGLSPERTVAALRAQDHASLTRIPGVGKKLAERLVVELKDKLDDLIAAAPAAGPVAAGPAAEDVLSALLNLGYQRPAALKAIETAVEKDAAAGEDFDLLFRAALKLIR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRPA_STAHJ
Sequence: MTKLFIPYIMGNKSFIKNMKILDENGADIIEIGVPFSDPVADGPIIMEAGNRAIKQGVTINYIFNELSNNKDEINCKYVLMTYYNIIVSYGEEAFFKECEKVGVYGVIIPDLPYELTQKLKHKISKFDVKVISLISMTANDDRIKEIVKHAEGFIYTVTMNATTGKNGTFHPQLKDKLKHLKAHTDIPVVAGFGIRTKEHIKDLATVADGVVIGSEIVKRFCQDNNEDTIHYLKQVRETLDTL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PACC1_XENTR
Sequence: MEAIRKELSRSYQELNEEAEPVAIDPEEAEDEEKEQEEAASAVAPDRDSDRSSPPVRFSRTCLKNFFSVLLILVYLLLMGVAVFLVYQTITDFRDKLKHPVMSVSYKEVNMYDAPGIALYPGKARLLSCEHHWYDHIPPLKDPGQPGENTCVTQDISYIDPYTNKTMKHALIVQGPRDVRRRELVFLQFHLNETKQDFSAIDYLLFSSYEAFLKSHDQVKFMQDCESSFSSWKFSGGFRTWVKMSLVKTKEEDGSQSVEFRQETSVVNFIDRRETPDKGDQLFFVVFEWKDPYIQEIQDIITANPWSMIALLCSVFLVLFKAADFAKLSVKWMIKVRRRHLKKRARELNHIS
What is the function of this protein?
Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH.
What are the official names of this protein?
Proton-activated chloride channel, PAC, Transmembrane protein 206.
What is the protein family that this protein belongs to?
Belongs to the proton-activated chloride channel family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_CAMLR
Sequence: MRHKININNHIEIFDTDKVAKQAAGAVLMQEKNAVVLATVAREEKMVEEDFLPLTVQYIEKAYAAGKIPGGYVKRETKPGDSETLSARIIDRSLRPLFPKGYAYPTQIVVMVLSADPEVDLQVMSLNAASVALYLSDIPIKAPVCGVRIGRINNEFVLNPSNSELKNSTLDLYVAGVKDELLMIEMRALSNKKDNQHCMNELSEDDTLKALDFASSAILRGSNEYEKAFAAYRKNSKLEFKIESDNIQIIDYIKNTYITKLKIAINQMAKSERASEILQIAKEIESESMAIENEWKFEDIEKALHVCKRELVRNQIINENKRADGRGLKDVRKIDIETNILPSAHGSCLFTRGQTQALVVATLGNDNDAQMSDMLTEKNPICEKFMVNYNFPGFSVGEASPIKAPGRRELGHGNLAKRALYPSVDADYIHTIRLVSEILESNGSSSMATVCGGALALRAAGVKSEKLVAGVAMGLVFEEEKYAILTDIMGLEDHDGDMDFKVAGSHDGITALQMDIKLGGIEQKVLQEALYQAKEARGYILNLMQEACEKIIVNEAILPKVEIFNVDPNKIPDIIGQGGKTIKDIIEKFEVNIDLDRDKGEVKIAGIDHNLISQSKEYILNLLHSKGSNKRRDKKEMPKFDIGEEFLGRVQKVVEFGVFVELKEGVDGLLHNSKIKEKLEVGHEIKVKVAEIKNGKVSLDLA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1077_METNO
Sequence: MLVHVPNVLTPAEIALCRARLEAGEWIDGRATAGQQAARAKHNLQIPEDSDTARELGELILRALGRSPLFNAAALPLRVLPPLFNRYDVGMSFRNHVDGAVRAIPGAGMRLRADVSTTLFLTDPDAYEGGELVIEDTFGSHAVKLPAGDMIVYPATSLHRVEPITRGSRWSAFFWSQSMVKDDGRRALLFDLDQGITGVRRKLSDDDPAAIALTSCYHNLLRRWAEM
What are the official names of this protein?
PKHD-type hydroxylase Mnod_1077.
Protein: ERPA_CROS8
Sequence: MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQINDGDMTIEKQGVSLVVDPMSLQYLVGGAVDYTEGLEGSRFVVNNPNATSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ENO_MYCMM
Sequence: MPIIEQVGAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVKKAVEAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNSILGVSLAVAKAASESAELPLFRYIGGPNAHILPVPMMNILNGGAHADTGVDIQEFMVAPIGAPSFSEALRWGAEVYHALKAVLKKAGLSTGLGDEGGFAPDVASTTAALDLISQAIEAAGFKPGVDVALALDAAANEFHADGSYTFEGTPRTAAQMTEFYAGLLGSYPLVSIEDPLYENDWDGWAALTAEIGDRVQIVGDDVFVTNPERLEEGIDRGVANALLVKVNQIGTLTETLDAVALAHHSGYRTMISHRSGETEDTIIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFVADPK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CGL2_COPCI
Sequence: MLYHLFVNNQVKLQNDFKPESVAAIRSSAFNSKGGTTVFNFLSAGENILLHISIRPGENVIVFNSRLKNGAWGPEERIPYAEKFRPPNPSITVIDHGDRFQIRFDYGTSIYYNKRIKENAAAIAYNAENSLFSSPVTVDVHGLLPPLPPA
What is the function of this protein?
Binds lactose (PubMed:8999822, PubMed:15062091).  May play a role in fruiting body formation (PubMed:8999822).  Displays toxicity towards the nematode C. elegans by binding to a specific Gal-beta-1,4-Fuc-alpha-1,6 modification of N-glycan cores on C. elegans intestinal cells (PubMed:20062796).
What are the official names of this protein?
Galectin-2, Cgl-II, Galectin II.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted, cell wall. Endomembrane system. Note=Detected in extracellular matrix, cell wall and cytoplasmic membrane-bound bodies.
Protein: SAT_THEON
Sequence: MVSKPHGGKLVRRLVAERTRERILSEQKEYPSVKIDHGRAIDLENIAHGVYSPLKGFLTSDDFQSVLDHMRLSDDTPWTIPIVIDIVEKTFDEGDAVLLYYEDIPIARMHVEEIYTYDKREFAQKVFKTTDPNHPGVAKVYSLGKYLVGGEIELLNEVPNPFAKYTLRPVETRVLFKERGWRTIVAFQTRNAPHVGHEYVQKAALTFVDGLFINPVLGKKKKGDYKDEVIIKAYETLFEHYYPKNAATLATVRYEMRYAGPREAIHHAIMRKNFGATHFIVGRDHAGVGDYYGPYEAWDMFENFPDLGITPMFIREAFYCRKCGGMVNAKICPHPKEFHVRISGTKLRKMIMAGEQPPEYMMRPEVYEVIRSFEKPFVE
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: CC038_BOVIN
Sequence: MTGLSYTEMEGCRNLLSLLDNDEIMALCDTITNRLVQPEDRQDAIRAILVYSQSVEELLRRRKVHREIIFKYLATQGVIIPPATEKHNLIQHAKDYWKKQLQPKLKETPEPVKTEDIRLSEQQEKEEKNAEKVDFRRLGEEFCQWFFELLNSQNPLLGPPQDEWGPQHFWHDVKLRFYYNTSEQNVIDYHGAEIVSLRLLSLVKEEYLFLSPNLDSHGQKYAASPHGLVMVGVAGTVHRGNTCLGIFEQIFGLIRCPFVENTWKIKFINLRIIGESSLAPGRLMKPAITFEPSDLEAFYNVNTLCGPVKYNSM
What is the function of this protein?
May be involved in apoptosis regulation.
What are the official names of this protein?
Uncharacterized protein C3orf38 homolog.
Protein: CA11_CONLE
Sequence: MGMRMMFIMFMLVVLATTVVTFTSDRALDAMNAAASNKASRLIALAVRGCCARAACAGIHQELCGGGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  Synthetic peptide inhibits alpha-6/alpha-3/beta-2 and alpha-3/beta-2 nicotinic acetylcholine receptors and causes uncoordinated movement when intramuscularly injected into goldfish (PubMed:18588930).  Has a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (Ala-Xaa-Ala instead of the conserved Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin Lp1.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNL1_PONAB
Sequence: MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKSDQLHLPKPG
What is the function of this protein?
Involved in pre-mRNA splicing.  Functions in association with cyclin-dependent kinases (CDKs).  May play a role in the regulation of RNA polymerase II (pol II).  Inhibited by the CDK-specific inhibitor CDKN1A/p21.
What are the official names of this protein?
Cyclin-L1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin L subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
Protein: RL9_RALPJ
Sequence: MQIILLEKVVNLGNLGDVVRVKDGYARNFLIPNKQARRATDSAIKEFEARRAELEKLAAEKLAAAQAEGEKLNGLTLQLSQKAGVDGRLFGSVTNHDIADALVAQGFKVEKAQVRMPNGPLKTVGDHPVVVSLHTDVAVDVTVLVQGDAV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NTRC_ECOLI
Sequence: MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes (PubMed:2874557, PubMed:3304660, PubMed:2574599, PubMed:1350679).  Activates transcription of many genes and operons whose products minimize the slowing of growth under nitrogen-limiting conditions, including genes coding for glutamine synthetase (glnA), transporters, amino acid permeases and catabolic enzymes (PubMed:11121068).
What are the official names of this protein?
DNA-binding transcriptional regulator NtrC, Nitrogen regulation protein NR(I), Nitrogen regulator I, NRI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_ENT38
Sequence: MNEFLPFSRPAMGPEELAAVSEVLQSGWITTGPKNQALEQAFCALTGNQHSIAVSSATAGMHVALMALGIQAGDEVITPSLTWVSTLNMIVLLGAEPVMIDVDHDTLMVTPQAIEAAITPRTKAIIPVHYAGAPVDIDAIRAVADRHGIPVIEDAAHAAGTYYKGSHVGNRGTAIFSFHAIKNMTCAEGGLIVTDDEQLANRMRSLKFHGLGVDAFDRQTLGRAPQAEVISPGYKYNLADINAAIALVQLKKLEKNNARRTEIAERYLTELANTPFLPLSQPAWAHKHAWHLFIVRVDEATCGISRNGLMDDLKAKGIGTGLHFRAAHTQKYYRERYPALVLPNTEWNSDRICSIPLFPTMTDDDVTRVIAALRDVAGY
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: RL31B_BURO0
Sequence: MKPGIHPDYREVVFQDMSNGFKFITRSTIQTRETIEHEGKTYPLAKIEVSSESHSFYTGQQKIMDTAGRVEKFKNKFGARANGKAAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: DRE2_TRIAD
Sequence: MESVSHLVSNGQSVLLVWSQGGQLDTLANFTSSLRERVGTNGTVAVENINRLSQSSYGSSTFDVALSNVVSSYCCKHTSEQLAQILKMLKPDCKCLLRDTSPSDQIRSELILAGFTNISIVAEDNATVKVNARKPNFEIGSSAALPFANKISLGGNSKMETAKMWTLSSQDFVDDDIDIIDENTLIEEDDFLKPDPSSLRSQECDSAKKKRKACKNCSCGLAEEIESEKKTNGNPVSSCGSCYLGDAFRCSSCPYLGMPAFKPGEKVALPSRLLQADV
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RL10_SULNB
Sequence: MTRTRKEELVAEMTAEFKDAGAIIVCDYKGMTVENLETVRNLAKDEDTKVKVVKNRLAMIALQNAGCEAVDFKDTNLVIWGDTQVLPCKIADKAATQFKDHFTIKTGLIQGEVASMETINAMAKLPTRDELIGMLLNVWNAPVQNFTIGLQALADKKESEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: IFGF2_PENRF
Sequence: MTILVLGGRGKTASRLAALLDQAKTPFLVGSSSASPSDPYKSSQFNWLKRDTWERPFEQAGKHGLGTISSIYLVGPPVMDIAPPMIEFVDLARAKGVQRFVLLSASTVEKGGHSMGQVHAYLDSLAEVEYVALRPTWFMENLLEDPSREWIKNENQIITATGDGKIPFVSADDIASVAFHCLTEWGSHKTEYVILGPELLSYGQVAEILTTILGKKIIHRSLTETGLAELLVKKAGIPADFAAMLSAMEVDVKNGPQEVLNNSVVEVTGNPPRYFKDVAEHEKHVWA
What is the function of this protein?
Festuclavine synthase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids (PubMed:28620689).  The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:28620689).  The second step is catalyzed by the methyltransferase ifgB that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptophan (PubMed:28620689).  The catalase ifgD and the FAD-dependent oxidoreductase ifgC then transform N-methyl-dimethylallyl-L-tryptophan to chanoclavine-I which is further oxidized by ifgE in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:28902217).  The chanoclavine-I aldehyde reductases ifgG and/or fgaOx3 reduce chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:28620689, PubMed:28902217).  The festuclavine dehydrogenases ifgF1 and/or ifgF2 then catalyze the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:28620689).  Hydrolysis of festuclavine by a yet undetermined cytochrome P450 monooxygenase (called ifgH) then leads to the formation of isofumigaclavine B which is in turn acetylated by ifgI to isofumigaclavine A (PubMed:28620689).  Penicillium roqueforti has interestingly at least two sets of genes for the consumption of chanoclavine-I aldehyde on three different loci, the OYEs ifgG/fgaOx3 and the festuclavine synthase homologs ifgF1/ifgF2 (PubMed:28620689, PubMed:28902217).  The reason for the duplication of these genes is unclear, probably to ensure the conversion of chanoclavine-I aldehyde by differential gene expression under various environmental conditions (PubMed:28902217).
What are the official names of this protein?
Festuclavine synthase II, Festuclavine dehydrogenase ifgF2, Isofumigaclavine biosynthesis cluster A protein F2.
What is the protein family that this protein belongs to?
Belongs to the fgaFS/easG family.
Protein: GLMU_BURTA
Sequence: MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAERVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRAATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASADELKIAEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSKAQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADGVTIGANCVIRNAAIAAGARVDAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVEVKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA24B_HUMAN
Sequence: MPVIAGGILAALLLLIVVVLCLYFKIHNALKAAKEPEAVAVKNHNPDKVWWAKNSQAKTIATESCPALQCCEGYRMCASFDSLPPCCCDINEGL
What are the official names of this protein?
Protein FAM24B.
What is the protein family that this protein belongs to?
Belongs to the FAM24 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y976A_HAEIN
Sequence: MAFIGVAILINGGKNNEGIDNISLFGCLLVLSAGIIFAAVLRWTQRVVAKVSTQAYTSVSIVLGTITTLPFTLLLTENWQISLNSTGIAGLLYLAIGCSWLAYWLWNKGLNSVDANISGVLVALEPLFGILFAVSLLGETLSFSAALGITIIMLATLGSTLLPKLLKKSV
What are the official names of this protein?
Uncharacterized transporter HI_0976.1.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSP_BRADU
Sequence: MMTAHRKSNGDTTNFARRHIGPSARDVAAMLETVGAKSVDALMAETLPASIRQAAPLDLGKPLSETEAIAHMGELAAQNQVFTSLIGQGYSGTILPAVIQRNILENPAWYTAYTPYQPEISQGRLEALFNFQTMICDLTGLDVANASLLDEATAAAEAMALAERHSRVEAKAFFVDKDVHPQTLAVMRTRAEPLGWNLIVGDPLTDLDKADVLGALLQYPGSSGALRDLRPAIAALKAKGALAIVAADLLALTLLASPGELGADIAIGSAQRFGVPMGYGGPHAAYMAVRDALKRSLPGRIVGLSVDSRGMPAYRLALQTREQHIRREKATSNICTAQVLLAVIAAMYAVYHGPEGLSQIARQVHRRAAVLAAGLRKLGFAPHSDSFFDTLSVDAGAKRAEIVARAAAEKINLGVGETALRIALDETTTPATVEAVWRAFGGQLAYAELDATTREALPEALKRTTAFLTHPVFHAHRSETEMLRYMRKLSDRDLALDRAMIPLGSCTMKLNATTEMMPLTWPEFGSLHPFAPREQAKGYHALFARLEKWLCDITGYDAISLQPNSGAQGEYAGLLAIRGYHAARGEAHRKICLIPSSAHGTNPASAAMVGMDVVVVACEKNGDVDVNDLRAKADKHANDLAAIMITYPSTHGVFEEHIREICDIVHGHGGQVYLDGANLNAQVGLSRPGDYGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLPGHPATRGDAPVGPVSAAPFGSASILTISYIYILMMGGEGLKRATEIAILNANYIAARLDAHFPVLYKNARGRVAHECIVDPRALKTTSGVTVDDIAKRLIDYGFHAPTMSFPVPGTLMIEPTESESKAELDRFCDAMIAIRKEIGEVEAGRFKIEASPLRHAPHTVHDIADDAWARAYSRAEGCFPDGVSRTDKYWSPVGRVDNVYGDRNLVCSCPPVSDYAEAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.