PharMolix/UniProtQA huggingface dataset:
Protein: XYN6_MAGO7
Sequence: MRTPAIVLALAPAAAFGQAALWGQCGGQGWTGAKTCVSGAVCQAQNEWYSQCVPGSGGGNPPTPQPTQPSNPPPSTGSGLNAKFKNKGKLYFGTSMDHYDLNKAQLTNIVKAQFGQITNENSMKWDAIEPSRNSFSWTNADAVVNFATANGKLMRGHTLLWHSQLPAWVSNINDRNTLTQVIQNHVTAMVTRYRGKILQWDVVNEIFAEDGSLRSSVFSRVLGEDFVGIAFRAARAADPNAKLYINDYNLDIANYAKVTRGMVEKVNKWVSQGIPIDGIGSQAHLAQPGGWNPASGVPAALRALAAANVKEIAITELDIAGASANDYVTVVNACLQISKCVGITVWGVSDAISWRPNDNPLLYDRNYQPKAAYTAIMNAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase 6, Xylanase 6, 1,4-beta-D-xylan xylanohydrolase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_ONYPE
Sequence: MQTKIKNLTTQFHTSLQKNKHDLDQLMTLDKEFLGKKGILFELTQELKSLPHAQKAVAGKLINVLKQEIILTLQKEKEILQRNQLNAKLLQEEIDPTLPGLKFFQGSAHPLNQIIEQIEDLFLSLGYEIKEGNEIETDFYNFEMLNMGKGHPARAMQDSFYIDPQKLLRTHTSNVQVKEMKARQGGPLKIISPGKVYRKDDDDATHSHQFMQLEGLVIDKNINFSHLKETLLLITKELFGTSQEIHLRPSYFPFTEPSIEVDLVITKKDGTKEYLEILGAGLVHPQVLKNANYDPEKYQGFAFGIGIERIAMIKYQIDNIRHFYTNDIRFLKQFARNTTNNENY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP168_BPTWO
Sequence: MLFFKEKFYNELSYYRGGHKDLESMFELALEYIEKLEEEDEQQVTDYENAMEEELRDAVDVIESQLEIIKDIVR
What is the function of this protein?
Targets the host DNA sliding clamp and inhibits host DNA replication.
What are the official names of this protein?
Gene product 168, gp168.
Protein: NEUFC_RAT
Sequence: MLRICGLGVVLSLAVAAAAVLAVWLMDWWGSHPSIRLFVPEELARYRGGPGDPGLYLALLGRVYDVSSGRKHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVNGLSSSEILTLHNWLSFYEKNYVFVGRLIGRFYGKDGLPTSELTQVEAMVTKGMEANEQEQREKQRFPPCNAEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNRGDLDNPNLEEYTGCPPLAVTCFFPL
What is the function of this protein?
Heme-binding protein which promotes neuronal but not astrocyte differentiation.
What are the official names of this protein?
Neuferricin, Cytochrome b5 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KLHDB_ANOGA
Sequence: MGDVLISDRPPSPARLSHTSEKHPRVTLQELNVLRRHRELCDVVINVKGRKIFAHRVILSACSPYFRAMFTGELEESRQTEVTICDIDENAMELLIDFCYTSHIVVEESNVQPLLPAACLLQLAEIQDICCEFLKRQLDPENCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMAWLKYNVADRRQHLAQVLQHVRMPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPETADWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGYLYAIGGSDGQCPLNTVERYDPRQNKWCAVSPMSTRRKHLGCAVFNNFIYAVGGRDDCMELSSAERYNPHTNSWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGTAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMW
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: NUOCD_SALPC
Sequence: MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVSDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYFA_COXB1
Sequence: MQNQLNALLQSAKKSVADAQSEIVLEEIRVDYLGKKGKLTELLKSVGQMPADQRPLLGKAVNEIKREIQQLLNAKSTQLREKSLQEKLNKEKVDITLRGRYDHLGAIHPISRVSERVSQLFSMLGFQIAEGPEIENEYYNFEALNIPADHPARTMADTFYFSGDKLLRTHTSPVQIREMEKQGVPIRLIALGRVYRRDLDQTHTPMFHQVEGLVIDKRSTFANLKGLLQQFLNCFFEKDVRLRFRPSYFPFTEPSAEVDIYQPRTDKWLEVLGCGMVHPNVLRNLNIDPDEYSGFAFGIGLDRLAMLRYEVTDLRLFFENDLRFLGQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPL2_ARATH
Sequence: MANKYFSSVLKSLLLLLHLVFLSKQHVDSASIVKFLPGFEGPLPFELETGYIGIGEEEEVQLFYYFIKSERNPKEDPLILWLTGGPGCSSISGLLFENGPLTMKLDVYNGTLPSLVSTTYSWTKTSSMIFLDQPVGTGFSYSRTQQFNKPSDSGEAKRIHEFLQKWLGKHQEFSSNPFYVAGDSYSGLVVPATVQEISKGNYECCNPPINLQGYVLGNPLTDYAIDSNSRIPFAHGMALISDELYESLKKTCKGEYTNVHPRNTQCLKFIEEFNKCTNRILQQLILDPLCETETPDCYIYRYLLTTYWANDATVREALQINKESIGEWVRCYRTIPYDNDIKSSMPYHVNNSISGYRSLIYSGDHDLEVPYLGTQAWIRSLNYSIIDDWRPWMIKNQIAGYTRTYANKMTFATIKGGGHTIEFKPEEASIMFQRWINGQPL
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_BRUAB
Sequence: MSGTDKVRVNVSQTAQTPLHTSAKLPKVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRLYDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDWAMRYGQPSIESITDRLLQQGCERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKHLATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVKLVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCLNDSEEGMKVIETLVRRELLGWV
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED18_CAEEL
Sequence: MDNLVDIDEDGTQEKLSVNSTPYQTQECVLYGSIFAKNVPDLERRLAGLCDPGCEEFFEHEMSFSLRSSGIMDIKTDIKLRRRFRTEHRIQNYWQLKYIGVPEPDQKCPTIVRKEISSLVHSQDMMTYAKSLGLRMDYEYMTQGKLWTKGNIKILHSILTSTSRAGTYDSNSIKSVSDSALVEISISLPESAEYMPAAKSLRDFADQLMPLVNMEKVDYWKKMFPAQAAPRR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AIR12_ARATH
Sequence: MASSSSSLLILAVACFVSLISPAISQQACKSQNLNSAGPFDSCEDLPVLNSYLHYTYNSSNSSLSVAFVATPSQANGGWVAWAINPTGTKMAGSQAFLAYRSGGGAAPVVKTYNISSYSSLVEGKLAFDFWNLRAESLSGGRIAIFTTVKVPAGADSVNQVWQIGGNVTNGRPGVHPFGPDNLGSHRVLSFTEDAAPGSAPSPGSAPAPGTSGSTTPGTAAGGPGNAGSLTRNVNFGVNLGILVLLGSIFIF
What is the function of this protein?
One-heme-containing cytochrome.
What are the official names of this protein?
Auxin-induced in root cultures protein 12.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DAPD_ECOSE
Sequence: MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER_DROIM
Sequence: EGSGGSGSSGNFTTGSNVRMSSVTNTSNAGTGTSGGGNSAAASGASVNAPPVTVTLTESLLNK
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: TRUB_CAMJ8
Sequence: MNKIFAAFKPRGLSSNAFLSTLKKKYKNKKAGYSGTLDPFAKGVLIVAFGQYTKLFRFLKKTPKTYKATLWLGVYSLSLDDQNIKEIKNIKEFDLANLQQIIDQMQGIISYTPPQFSAKRINGTRAYELAKKGIEANLKPCQMEVFDCKILSYNHPFLNIEITVSEGAYIRSYCELFARKLGINATLSSLERIKEGKFVYNNEKSLNVLKYINLKPNFIKDLNKLENGAKIFVEELKFHDEGDYYIETEKYFSIINIKENTVKYLLNKVEKC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ALR_BRUO2
Sequence: MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVALKPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVTLLSRIDIKFAISHLANGDEPGNAANARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHDFSDKVAHENKKPKHSILPVLPLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRLPIIGRVSMDSITLDVTSLPEGTLKLGSLVELIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PHZS_LYSAN
Sequence: MTTATQTDIVIAGAGIGGLTTALALHAQGIERVVVLESANEIRPLGVGINVQPAAIAQLFALGLGEAIAATGIATRELRYLDHAGITLWTEPRGLAAGDPYPQYAIHRGELQMLLLAAVRERLGADTVRTGLRVQDFEHTRTGIRVHAQERGNGGSTVSFEATALVGADGLHSAVRARLHPDRCELLPARIQMWRGLTEVDEFLDGRSMIVANDDRSTRLIAYPCSARHAQHGRALINWVCMVPDVAQDLTREASWDCSGQLKDVLPYFADWKFGWLDVPDLLSRSTQILEYPMVDRDPLPRWGIGRATLLGDAAHLMYPVGANGASQAILDAVSLANELGDNSDTVEALQRYEAVRRPPTTAIVQANRDRDTAERAIATRPDPEKTAALAAITSSYRSIVDRSHVQ
What is the function of this protein?
Involved in the biosynthesis of phenazine natural products including myxin, an N(5),N(10)-dioxide phenazine antiobiotic, which has antimicrobial activity.  Catalyzes the decarboxylative hydroxylations of phenazine 1,6-dicarboxylic acid (PDC) to produce 1,6-dihydroxyphenazine (DHP) (PubMed:27145204, PubMed:29510028).  Low activity with phenazine 1-carboxylic acid (PCA) to produce 1-hydroxyphenazine (PubMed:29510028).
What are the official names of this protein?
Phenazine 1,6-dicarboxylic acid hydroxylase PhzS, Flavin-containing monooxygenase, Phenazine 1-carboxylic acid hydroxylase.
Protein: RS8_THET8
Sequence: MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit central domain.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MOBA_HELPG
Sequence: MKNPIIDNIPCVLLAGGKSSRFITNNIQTNKALMPLKSYSSLLEYQYTRLLKLFKKVIISTKKSYELNAPYLLEKESDLFSPLFGIHNAFLTLQTPYIFFIPIDTPLVSFESIKALCGIKNFSVVYAKSPTKEHYLISLWHQSTLNALNYALKTQNYRLSDLIKNASSTAIHFDKEEEFLNLNTLKDYELAVQILKEGSNG
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_YERE8
Sequence: MPNKSPTRTLYALFGGTFDPIHYGHLKPVETLAQQVGLQHIILLPNHVPPHRPQPEANAQQRLKMVELAVAGNPLFSVDSRELLRDTPSFTIDTLESLRKERGAERPLAFIIGQDSLLSLHKWHRWQSLLDVCHLLVCARPGYAQTLETPELQQWLDAHRVFDPQALSLRPHGAIYLADTPLLDISATDIRHRRHNGESCDDLLPRAVQRYIELQGLYRG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: COX1_HIPAM
Sequence: MFMNRWLFSTNHKDIGTLYLLFGAWAGMAGTGLSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPVLYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFVIMFVGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNTISSMGSFISLTAVVLMVFIIWEAFVSKREVLAVDLTTTNLEWLNGCPPPYHTFEEPAYVNLTS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GPMA1_LATSS
Sequence: MANLVIVRHGESVANQLKTYTGWSDVALTAKGRQQAHQVGRQIKDAGFQFSHVHTSLLKRAILTSYIVLEELDQLALPMTKSWRLNERHYGALRGLNKDTTRTIFGVHQVARWRRSYTALPPLLIRSSTARRYRLVPRKSRPRGESLAQATQRLLPYWQDQVVPGLLAGQDQLIVAHGSTLRALIKVIEQISDQAIDGVEVANGEALYYQFGTDLTVLKKGRLALGSETDEEKEN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1, BPG-dependent PGAM 1, PGAM 1, Phosphoglyceromutase 1, dPGM 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RUVA_PSYWF
Sequence: MIGLIEGRVCHLSAPVACLMTASGVGYEVELPLPDFCQLQLEAMASLWTHLHVREDAQLLYGFLHPTERDVFRQLIRVNGVGAKMALAMMSTFSATELKHCIDTENDAALTRVPGIGKKTAQRLLIELKGKFDHIQSDMSLLTEVEQQIGIAANSEGVILAEVESALISLGYRDKEAQQAIKAARETDAGQQLVDTQSLLKLTLKQLSNF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ITRY_MAIZE
Sequence: SAGTSCVPPPSBGCHAILRTGIPGRLPPLZKTCGIGPRQVZRLQBLPCPGRRQLABMIAYCPRCR
What are the official names of this protein?
Trypsin inhibitor.
Protein: KHSE_BUCBP
Sequence: MIKIYAPASIGNVGVGFDVLGAAISPIDNSLLGDVITITSSKQFSLTSTGTFSNQLPKDINKNIVKKCWTYFCKILKKNLPVSITLEKNMPIGSGLGSSACSIVATVVAINTFFNKPINNFELLKLMGKLEGKISGSVHYDNVAPSYLGGMQLIINKNDIVCQKISIFKNWLWVIAWPGISISTEQARTLLPLQYSKKVCIQHSQNLAGFIHATYTHQSKLASMFMHDIIAEPYRIKLLPYFLKTKQIIIDMGAIACGISGSGPAIFAVSDNLLTAKKIATWLTNYYLTNDRGFVHICKIDTIGARKIGL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP7A_DROSI
Sequence: MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKRLIGRRFDDATVQSDMKHWPFEAFAENGKPRIRGTFDVSVLTIEDGFEVKATAGDTHLGREDFDNRLVNHLVQEFQRKHGKDLGQNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGT
What are the official names of this protein?
Heat shock 70 kDa protein cognate 1, Heat shock 70 kDa protein 70C.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EFTS_CLAM3
Sequence: MANFTAADVKELRDRLGAGMMDSKNALVEADGDIEKAIEILRLKGQKGNAKRGDRSTAEGLVAASTQDGAATLIELACETDFVAKNDKFIALSESVLAAVVAAGASTVEEALQAPAGEQTVDQLISDQAAILGEKIALRRVARLAGEHQEVYLHRTSKDLPPQVGVVVDYSGTDAETARSIAQHIAFANPEYLAREDVPADKVEAERAIVTEISRNEGKPEAALPKIIEGRLTGFFKQVALLEQDYAKDNKQSVKKVVEAAGLTVTGFARFKVGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB1_STRCO
Sequence: MGLEEKLPSGFLLTTVEQAAGWVRKSSVFPATFGLACCAIEMMTTGAGRYDLARFGMEVFRGSPRQADLMIVAGRVSQKMAPVLRQVYDQMPNPKWVISMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLMDAILKLHQKIQSSKLGVNAEEAAREAEEAALKALPTIEMKGLLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNPA_HAEIG
Sequence: MVKLNFSRELRLLTPIQFKNVFEQPFRASTPEITILARKNNLEHPRLGLTVAKKHLKRAHERNRIKRLVRESFRLSQHRLPAYDFVFVAKNGIGKLDNSAFAQILEKLWQRHIRLAQKS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: TTCA_BRUME
Sequence: MNAFDADITEHADSSGCHPLFRDVPATVEFNKLRKRLVRLTRQAIEDFAMVKPGDRWMVCLSGGKDSYGLLALLLDLKWRGLLPVELLAVNLDQGQPNFPKHILPDFLTRYGIEHRIEYQDTYSIVTDKLPETSTYCSLCSRLRRGNLYRIAREEGCSAIVLGHHREDILETFFMNLFHGGRLAAMPPKLLNDEGDLMVFRPLAYAAEDDLEKFANAMQFPIIPCDLCGSQDGLQRNAMKAMLIDIEKRMPGRKDTMIRALTNVRPSHLLDRKLFDFAGLMANGEKGSDDALW
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.