PharMolix/UniProtQA huggingface dataset:
Protein: SRKA_ECO57
Sequence: MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLFEDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAIQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY
What is the function of this protein?
A protein kinase that phosphorylates Ser and Thr residues.  Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species.  Probably involved in the extracytoplasmic stress response.
What are the official names of this protein?
Stress response kinase A, Serine/threonine-protein kinase SrkA.
What is the protein family that this protein belongs to?
Belongs to the SrkA/RdoA protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNF8_VANPO
Sequence: MNGSLNIRGLPKLTTSTSISVSSTSASSTLSTTTLSSNSIISSITTDTSGTSTSSRDVSSGQSTLNSISTTSSIIVPSITPPSAAKNPNVWHSEDSDGTVFIAVGSIIGGIFGGVLIWWMITSYLSHVKTKKAYHSDMEEQYMSHLNGGSPHKVGSYHDDKSKIENPFSSFYMDDLESSNKKKYSRVSLVSDNPFDEDLDYALDTTEQVRYNPIQDETNHYANKKDTLFISPTKEVLQQQRQRRESKLFDNPSELPSTPPSNFKTLMLKPERSASPERKSRSPIRQHRKNNSSVQLTPLKLDSGEDDFKKTPTKKKNVNNSNNNNKHKKTPSMYLDDMLENDN
What are the official names of this protein?
Vacuolar membrane protein Kpol_1003p17.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: SPIKE_ADEM1
Sequence: MVEALNAVYPYDLALLPEDYEKTTAPDAVQAANAARPFLNPVYPYQQPVAGDFGFPIVMPPFFNSYDFTSIHGNTLSLRLNKPLKRTAKGLQLLLGSGLSVNADGQLESSEGISEADAPLQINDGVLQLSFGEGLSVNDHGELESKGKVEAVTLPLALQDHVMSLSFGQGLQVNDQGQLEALAMVHSTSAPLKVTNNNLELALGRGLIVDDQGQLRLAPNLLWPESPLAIEQGTNHLILFYNQSLDVEDGKLTLPEPFDPLTLDGGRLRMQLAPNSGLAVTEKGSLGINWGEGIQVKEQKITLKVTPANGLAVTEQGGLNINWGNGIKVDEQKVTLKTSNEFALTENGLYLTSPLNPIEVNQHGQLGIALGYGFHAHRGYLELTPQTLWTGLPIGNNGTFHTKQDCKIFLSLTRLGPMVHGTFMLQAPQYELTTNGMREITFSFNSTGGLEQPAPVTYWGALDPPPTAKAAEIENQKRVKKRAAPDPPVEPPPKRRGDLAVLFAKVAEQAMELAKEQAVQAQPPEHVNTDWADHMNLLRFMPNTLVYPTAATIAANLQFHDTRLSLRRATLKIRLNGSPDSAYQLGFMLELVGTQSASIVTDTISFWYYAEDY
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: LRC8E_HUMAN
Sequence: MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPNHELQENLSEAPCQQLLPRGIPEQIGALQEVKGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENQKGPAATERAAATIVAMAGTGPGKAGEGEKEKVLAEPEKVVTEPPVVTLLDKKEGEQAKALFEKVKKFRMHVEEGDILYTMYIRQTVLKVCKFLAILVYNLVYVEKISFLVACRVETSEVTGYASFCCNHTKAHLFSKLAFCYISFVCIYGLTCIYTLYWLFHRPLKEYSFRSVREETGMGDIPDVKNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNAAGRLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKMEEE
What is the function of this protein?
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731).  The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine (PubMed:24790029, PubMed:26824658).  Mediates efflux of amino acids, such as aspartate, in response to osmotic stress (PubMed:28193731).  The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol (PubMed:33171122).  Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731).  Also plays a role in lysosome homeostasis by forming functional lysosomal VRAC channels in response to low cytoplasmic ionic strength condition: lysosomal VRAC channels are necessary for the formation of large lysosome-derived vacuoles, which store and then expel excess water to maintain cytosolic water homeostasis (PubMed:33139539).
What are the official names of this protein?
Volume-regulated anion channel subunit LRRC8E, Leucine-rich repeat-containing protein 8E.
What is the protein family that this protein belongs to?
Belongs to the LRRC8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Lysosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In the absence of LRRC8A, resides primarily in the endoplasmic reticulum (PubMed:24790029, PubMed:33139539). Requires LRRC8A for localization at the cell membrane or lysosome membrane (PubMed:24790029, PubMed:33139539).
Protein: ATPF_PLAOC
Sequence: MQNLTDSFVSLGHWPSAGSFGFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILSTIRNSEELRGGAIEQLEKARARLRKVEMEADEFRVNGYSEIEREKLNLINSTYKNLERLENYKNETIQFEQQRAINQVRQRVFQQALQRALGTLNSCLNNELHLRTISANIGMFGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MINE_HELMI
Sequence: MLDFLNRMFSRDGGNSKNIAKERLRLVLVHDRSSVSPEIVEALKEDLIKVISSYMEIDERSLEVNLNNDEASVALVANIPVLGLKRRNV
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: TRPA_ALCBS
Sequence: MRRIERCFQRLDGENRKALIPFVTAGDPVKDVTVPLMHAMVDAGADIIELGVPFSDPMADGPVIQLACERALQHNTSTRDVLAMVKIFRETNTQTPVVLMGYLNPVEVMGYESFAKAAEDAGVDGVLLVDLPPEEALEVRPVMDAHGLDMIFLVAPTTSDTRIKLIGEAGSGYLYYVSLKGVTGSATLNVEEVASRVETIRNLAQLPIGVGFGIKDAESAQAVSRVADGVVVGSALVNQIAENKNTPDAINDAVGGILSAMRKAMDQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HIS5_PROM4
Sequence: MNTNIGIIDYGMGNLHSVQQSFKRLDQSIRIVKSPNDVHECNALILPGVGSFDPAMENLRRTDLIPKIKSWVKDGKPLLGICLGLQLIFESSEEGNSEGLGLLKGKVCNLPRNTKERIPHMGWSLLKQIKECPLLDNENTSRWMYFVHSYSAIPSPEDLAATVSFGDSEVTAIVWKDSLGACQFHPEKSGKSGQRLLSSWLKWLHEKNSDLS
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_MAGSA
Sequence: MSQAALRLVDKDTMDRQKALEAAVSQIERAFGKGSIMKLGGKDQVVETEVVSTGSLGLDVALGIGGVPRGRIIEVYGPESSGKTTLALHIIAEAQKKGGTCAFVDAEHALDPSYARKLGVNLDELLISQPDAGEQALEIADTLVRSGAVDVLVVDSVAALVPRAELEGEMGDNHMGLHARLMSQALRKLTGSVSKSKTIVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRMEIRRVGAIKDRDEVVGNQTRVKVVKNKLAPPFKVVDFDIMYGEGISKMGELIDLGVKANVVEKSGAWFSYNSTRIGQGRENAKTFLRENPAMAAEIEGAIRQNAGLISEALAGGPGDLDGTPVEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CANB_YARLI
Sequence: MADERSKLEQAGEGTNFSSDEIDRLRKRFMKLDTDASGILETNEFLSLPGVAANPLASRLMDVFDENHSGDVDFQEFINGLSTFSTKGNKKEKLRFAFKVYDIDRDGYISNGELFIVLKMMVGNNLKDAQLQQIVDKTIMEADKDGDGKISFEEFEAQVGGTNVYQSMTLDLF
What is the function of this protein?
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase.  Confers calcium sensitivity (By similarity).
What are the official names of this protein?
Calcineurin subunit B, Calcineurin regulatory subunit, Protein phosphatase 2B regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: YHBP_SALTY
Sequence: MDTLTAIGRWLAKQHVVTWCVHHEGELWCANAFYLFDAQNVALYLLTDDKTRHAQMSGACAPVAGTVNGQPKTVARIRGVQFKGEIRRLEGQESDAARKAYLRRFPVARVLPAPVWEIRLDEIKFTDNTLGFGKKLHWLRDSRAQQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: WHIA_BREBN
Sequence: MSFAAHTKKELTMMEGADCCSKAELSALIRMNGSLQFGAGRLVLDVTTENAAIARRIYTLIKRLFQIHAELLVRKKMRLKKNNVYIVRIPNKANEILQDLGIMDQSLSFIPGIAPEIVKKSCCRAAYLRGAFLAGGSVNHPEASSYHLEIFTSYQDFCEALTKIANRYKLNAKCIERKKGYVLYIKEGEKITEFLSLIGAHQALLYFEDVRIVKDMRNSVNRLHNCEIANINKTVNAATRQMENIQLIDQEMGLENLPKRLREVAELRVAHPDINLKELGEMVPSGVVSKSGINHRLRKINEIADKIREKQNISM
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: SDCB2_RAT
Sequence: MSVLYPSLEDLKVGQVIQAQARASPMMPTVMPTLPASMASAPPLSELYPNLAELESYMGLSLSSQEVQKNLSQIPDGDNMVITSPGPGQVTAPVSGNDLGVLRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWSTHKAQKALKKASAEKIVMVVRDRPFQRTVTMHKDSSGQVGFFIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVIGLKDKKIIEILTTAGNVITLTIIPTVIYEHMIKKLSPLLLHHTMDHSIPDT
What is the function of this protein?
Binds phosphatidylinositol 4,5-bisphosphate (PIP2).  May play a role in the organization of nuclear PIP2, cell division and cell survival.
What are the official names of this protein?
Syntenin-2, Syndecan-binding protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cell membrane. Nucleus speckle. Note=Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments. Colocalizes with TM4SF1 in the apical region of the cell. Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments. PIP2 plays an important role in the distribution of SDCBP2.
Protein: PHS_MYCS2
Sequence: MAVLSNDQVDAALPNLPGWERAAGALRRSVKFPTFLDGIDAVRRVAEFAEEKDHHPDIDIRWRTVTFALVTHAAGGITEKDVQMAEEINRILSD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: CARA_STAAR
Sequence: MQSKRYLVLEDGSFYEGYRLGSDNLTVGEIVFNTAMTGYQETISDPSYTGQIITFTYPLIGNYGINRDDFESLVPTLNGIVVKEASAHPSNFRQQKTLHDVLELHQIPGIAGVDTRSITRKIRQHGVLKAGFTDRKEDIDQLVKHLQQVELPKNEVEIVSTKTPYVSTGKDLSVVLVDFGKKQNIVRELNVRGCNVTVVPYTTTAEEILAMAPDGVMLSNGPGNPEVVECAILMIQGILGKIPFFGICLGHQLFALSQGASSFKMKFGHRGANHPVKNLETGKVDITSQNHGYAIDIDSLKSTDLEVTHLALNDGTVEGLKHKTLPAFSVQYHPEANPGPSDSNYLFDDFVAMMTNFKEKERHINA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RL36_LEPIN
Sequence: MKVRTSVKKICSSCKVIRRKGVIGVICTNPKHKQRQA
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TFPT_HUMAN
Sequence: MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPASD
What is the function of this protein?
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
TCF3 fusion partner, INO80 complex subunit F, Protein FB1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PARIS_DROME
Sequence: MAEICRVCMDISGKLVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHILEIHK
What is the function of this protein?
Transcription repressor that inhibits transcription of srl/PGC-1-alpha to negatively regulate mitochondrial biogenesis and thereby promotes neurodegeneration (PubMed:27819722, PubMed:32138754).  In neurons, functions downstream of the Pink1-park pathway and is likely to act as part of the Pink1-park homeostatic mechanism that maintains mitochondrial quality and function through degradation (mitophagy) and synthesis (biogenesis) (PubMed:32138754).
What are the official names of this protein?
Zinc finger protein Paris, Parkin-interacting substrate.
Protein: EFP_PARP8
Sequence: MKIAQELRTGNVVMIGNDAMVVQKAEYNKSGRNAAVVKMKFKNLLTGAGMETVYKADDKFDVVVLDRKEVTYSYFADPMYVFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAISVELPTTLVREIIYTEPAVKGDTSSGKVLKTAKLNTGFELQVPLFCNIGDKIEIDTRTNEYRSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH2_KLULA
Sequence: MFRQSIVKQSCRFLATKKQPSIGRYTGKPNPKTGKYTVSFIEGDGVGPEISKSVKAIFSAAKVPIEWESCDVSPIFVNGLTTIPDPAVASINKNLIALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGYKTTYENVNLVLIRENTEGEYSGIEHVVAPGVVQSIKLITQDASERVIRYAFEYARAVDRSKVLVVHKSTIQRLADGLFVDVAKKLSSEYPDIELQTELLDNTVLKTVQHPEAYDDVVVVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHTVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGLTEHADKIEKAVLTTIASDAKNRTGDLGGSASTSSFTDAVIERL
What is the function of this protein?
Performs an essential role in the oxidative function of the citric acid cycle.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial, Isocitric dehydrogenase, NAD(+)-specific ICDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS5_GLOC7
Sequence: MAKRRKSSRTKEKETNWQERVIQIRRVSKVVKGGKKLSFRAIVVVGNETGQVGVGVGKAGDVIGAVRKGVADGKKQLIEVPLTKASSIPHLTNGASGGASVIMRPAAPGTGVIAGGAVRTVLELAGVKNILAKQLGSDNPLNNARAAINALETLRTFSEVAKERDVPLEHIYS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NUOD_CITBB
Sequence: MASEIMTLNMGPQHPSTHGVLRLVVELDGEVIQKITPHIGYLHRGIEKLSEHRTYHQALPLTDRMDYLAPMHNNLGYVLAVEKLLGIEVPERAETIRVIMAELTRLKSHLVWIACHALDIGAMTVFIYAFREREKIMELYEMVSGARMTSNYFRVGGLSRDLPAGFESAVQEILDTFPGHFDTYEGLLTKNTIWLQRTIGNGVISADDAIDFGISGPALRGSGVDFDLRRDLPYSGYEKYDFKVPVGENCDTFDRYKVRLVEMREAVKIIDQAMKRLKPGPILADAPQVCYPPKESVYNSIEGLIHHFKIASEGFPVPEGEVYQGVENPKGELGYYMVSDGGSKPYRMRVRPPSFVNLGAIEKMAKGSMIADLVAVIGTLDIVLGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPSB_STRP8
Sequence: MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNAQIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVFGKQIIE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: Y494_STAEQ
Sequence: MAEDKFEQAKGNIKETVGNATDNKELEKDGKGDKASGKAKEAVENVKEKANDVIDKFKGNKGD
What are the official names of this protein?
UPF0337 protein SERP0494.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: ACPS_RICBR
Sequence: MIIGVGTDIVQIPRIEKIIKLYPEIFPKRILNTEELKKFALLKKESHVTFLAKRFAAKEAISKAFGVGIGRGINFKDITLLNDELGKPIVKIDSLYTQKLPPFNIHLSLSDDYPICVAFVVVEKIIL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PSEPK
Sequence: MKLNDLSPAPGSRREKHRPGRGIGSGLGKTGGRGHKGQTSRSGGSIAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRLSELAKVEGDVISVQSLKDANVINQHIQRVKIMLSGEVTRAVTIKGIAATKGARAAIEAAGGKFEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MBD_THEAC
Sequence: MDTAGMEHSVSWISSNSDELILRSWISSRMDIAELHRAGDDIKEMMKSEGYYSEPSKYEAELSDGNITFAYSYPIKAFEKFLGYYDRENRIAFNPSISMRTDFSFCLAACRYRKNGKTDTVVLDGYADNKYYKKAKFALDKFRSEYSINGSFDFYIKRYRRYQKAKGLSESSAVAAAVSRALISNVFGDDAAKDDIFVSRYARLVSGSGTRAAHDGISMWLSYPGMDSRDCVAFKVGKSNENLNYGVFPKYSDVATDNAHSIAVNSVFYGTWVSEKFSNVKRLISDHFDINDLLKIGENDMLRLNSILMSGGLIIQTPDSLRILKEILKFKSKNEGFYFTADTGPSIAIFSFDRSLIDEFRENVNDEYIEGSYDFKGYNNRMRDFIREAQEYFTQTPGEDEEDRL
What is the function of this protein?
Catalyzes the ATP-independent decarboxylation of (R)-mevalonate 3,5-bisphosphate to isopentenyl phosphate.  Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate.
What are the official names of this protein?
Mevalonate 3,5-bisphosphate decarboxylase, MBD, Bisphosphomevalonate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the mevalonate 3,5-bisphosphate decarboxylase family.
Protein: HIP_MARGR
Sequence: EVPANAVTESDPTAVALKYHRNAEASERVAAARPGLPPEEQHCENCQFMLPDQGADEWRGCSLFPGKLINLDGWCASWTLRAG
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein, HiPIP.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VINT_BPMD2
Sequence: MQASYVSPIDGQRYFGPRNYDNRMDAEAWLASEKRLIDNEEWTPPAEREKKAAASAITVEEYTKKWIAERDLAGGTKDLYSTHARKRIYPVLGDTPVAEMTPALVRAWWAGMGKQYPTARRHAYNVLRAVMNTAVEDKLVSENPCRIEQKAPAERDVEALTPEELDVVAGEVFEHYRVAVYILAWTSLRFGELIEIRRKDIVDDGETMKLRVRRGAARVGEKIVVGNTKTVRSKRPVTVPPHVAAMIREHMADRTKMNKGPEALLVTTTRGQRLSKSAFTRSLKKGYAKIGRPDLRIHDLRAVGATLAAQAGATTKELMVRLGHTTPRMAMKYQMASAARDEEIARRMSELAGITP
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: NTPPA_PARUW
Sequence: MKIILGSQSPRRKEILNFFSLPFEQVSPVFDEETVPFGGNPEHYVLSLSAGKTKSLRYQFPKDILISADTIVYKEGKVFGKPRSKEEAFQNLRELAGHWHSVYTGVNVSNENQEIQQFEETKVLFNSLTDDEIHQYQEKIHCADKAGGYMVQGAGSLIIKKLEGCYYNVMGLPINTLRLCLSEIGIDLWKYLKD
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.