PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_MARMM
Sequence: MNHDVMNIFNPAAEGPSFDRIRIALASPEKIHSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRIKYKGIVCEKCGVEVTLARVRRERMGHIELAAPVAHIWFLKSLPSRIAMILDMALKDVERVLYFENYVVIEPGLTPLQPFQLLSEEEYMEAQDEYGEDAFTAGIGAEAVREILINMDLEAECAKVREDMKETGSELKLKKYAKRLKLMENFLTSGNRPEWMIMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHECGLPKKMALELFKPFIYARLDAKGLSGTVKQSKKLVEKERPEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARTLMMSTNNILSPANGKPIIVPSQDIVLGLYYLSIEKDNEPGEGMAFGSRAELEAALESDVITLHTKIKARWEGIDVDGNKITKVIETTPGRKMLVDLLPKHAKMQPEMIGELLTKKAIGALIDQVYRHCGQKATVIFCDQIMGLGFKEAAKAGISFGKDDMLIPDAKADLVGATRDMVSDYEQQYVDGLITKGEKYNKVVDAWAKCTDNVADAMMDEISKTSVGEDGRTSEVNSVYMMAHSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITEEDCGTSEGFEIQAVVDGGDVVVSLEQRILGRTLAAEVKDPASGEVICPADTYVDEDLAMAIEMAGVQSVIARSPLTCETRVGVCATCYGRDLARGTRVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGTAQVSEQSFIEAGSEGKVTFKNPSTVTNSDGDLIALSRNMQLVIVDTEGKERESYKLGYGTKLKVKEGDKTTRGQRLGEWDPYTAPVVSEVGGKVKFVDIAEGVSVKEETDEATGIASKVVIDWRGSAKANALQPTIVVQDENGEPIKLSSGSTASYMLAVGAILSVADGDTVRPGDIVARIPTEGAKTRDITGGLPRVAELFEARRPKDHAVIAEITGRVEFGRDYKNKRRIAIVPEGDEAEKVEYLVPKGKHLTCQEGDVIQKGEYLLDGHPAPHDILAILGVPALANYLIDEIQEVYRLQGVPINDKHIETIVRQMLQKIEVKDPGESTYLAAEQVDKIEFIETNERLEAEGKRMATGDPVLLGITKASLQTRSFISAASFQETTRVLTEAAVQGKEDTLEGLKENVIVGRLIPAGTGAIMRQYQVIADDLDADMLAEREAAVEAEGLPTEIAEAAAEEMAAEEGAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NUOB_SODGM
Sequence: MDYTLTRAEPDGDNERYPLQKQEIVADPLEQHVHRSVYLGKLERALHNAVNWGRGNSLWPYNFGLSCCYVEMTTSFTAVHDVARFGSEVIRASPRQADFMVVAGTPFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYIQALLLLKESIGKERRPLSWVVGDQGVYRANMESERQRKHGERIAVTHLRTSDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURG_CAUVC
Sequence: MSKLAVVAAGGTGGHMFPAQALAEALAARGWRVVLATDDRGALYADKFPAEERLALSAATAKSNDPLGMIKAGFVVLQGVMEARAAFKRLDPAVVVGFGGYPALPALLGALSQGRPTVIHEQNAVLGRVNRFLAPRVNEVACAFPILEKATPAVKACAHVVGNPVRPPVRALFDVPYLAPEVQLRVLVTGGSQGARLLSELIPEAVAKLPEEMRGRLKVFQQARAESMEQARKVYRNAMVECEVAPFFRDMAGYLRQSHLVIGRSGASTCTELAVAGRPSILIPLKIAADDHQRFNARLLEEAGGAAVCLEDELTVDVMAAALKALLSKPERLEKMAAGARSAAKPNAAEELADLVEKTAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: L_NDVB1
Sequence: MASSGPERAEHQIILPESHLSSPLVKHKLLYYWKLTGLPLPDECDFDHLILSRQWKKILESASPDTERMIKLGRAVHQTLNHNSRITGVLHPRCLEELANIEVPDSTNKFRKIEKKIQIHNTRYGELFTRLCTHIEKKLLGSSWSNNVPRSEEFSSIRTDPAFWFHSKWSTAKFAWLHIKQIQRHLIVAARTRSAANKLVMLTHKVGQVFVTPELVVVTHTNENKFTCLTQELVLMYADMMEGRDMVNIISTTAVHLRSLSEKIDDILRLIDALAKDLGNQVYDVVSLMEGFAYGAVQLLEPSGTFAGDFFAFNLQELKDILIGLLPNDIAESVTHAIATVFSGLEQNQAAEMLCLLRLWGHPLLESRIAAKAVRSQMCAPKMVDFDMILQVLSFFKGTIINGYRKKNAGVWPRVKVDTIYGKVIGQLHADSAEISHDIMLREYKSLSALEFEPCIEYDPVTNLSMFLKDKAIAHPNDNWLASFRRNLLSEDQKKHVKEATSTNRLLIEFLESNDFDPYKEMEYLTTLEYLRDDNVAVSYSLKEKEVKVNGRIFAKLTKKLRNCQVMAEGILADQIAPFFQGNGVIQDSISLTKSMLAMSQLSFNSNKKRITDCKERVSSNRNHDPKSKNRRRVATFITTDLQKYCLNWRYQTIKLFAHAINQLMGLPHFFEWIHLRLMDTTMFVGDPFNPPSDPTDCDLSRVPNDDIYIVSARGGIEGLCQKLWTMISIAAIQLAAARSHCRVACMVQGDNQVIAVTREVRSDDSPEMVLTQLHQASDNFFKELIHVNHLIGHNLKDRETIRSDTFFIYSKRIFKDGAILSQVLKNSSKLVLVSGDLSENTVMSCANIASTVARLCENGLPKDFCYYLNYIMSCVQTYFDSEFSITNNSHPDLNQSWIEDISFVHSYVLTPAQLGGLSNLQYSRLYTRNIGDPGTTAFAEIKRLEAVGLLSPNIMTNILTRPPGNGDWASLCNDPYSFNFETVASPNIVLKKHTQRVLFETCSNPLLSGVHTEDNEAEEKALAEFLLNQEVIHPRVAHAIMEASSVGRRKQIQGLVDTTNTVIKIALTRRPLGIKRLMRIVNYSSMHAMLFRDDVFSSSRSNHPLVSSNMCSLTLADYARNRSWSPLTGGRKILGVSNPDTIELVEGEILSVSGGCTRCDSGDEQFTWFHLPSNIELTDDTSKNPPMRVPYLGSKTQERRAASLAKIAHMSPHVKAALRASSVLIWAYGDNEVNWTAALTIAKSRCNVNLEYLRLLSPLPTAGNLQHRLDDGITQMTFTPASLYRCHLTFTYPMILKGCSLKKESKRGMWFTNRVMLLGLSLIESIFPMTTTRTYDEITLHLHSKFSCCIREAPVAVPFELLGVAPELRTVTSNKFMYDPSPVSEGDFARLDLAIFKSYELNLESYPTIELMNILSISSGKLIGQSVVSYDEDTSIKNDAIIVYDNTRNWISEAQNSDVVRLFEYAALEVLLHRSYQLYYLRVRGLDNIVLYMGDLYKNMPGILLSNIAATISHPVIHSRLHAVGLVNHDGSHQLADTDFIEMSAKLLVSCTRRVISGLYSGNKYDLLFPSVLDDNLNEKMLQLISRLCCLYTVLFATTREIPKIRGLTAEEKCSILTEYLLSDAVKPLLSPDQVSSIMSPNIITFPANLYYMSRKSLNLIREREDRDTILALLFPQEPLLEFPSVQDIGARVKDPFTRQPAAFLQELDLSAPARYDAFTLSQIHPELTSPNPEEDYLVRYLFRGIGTASSSWYKASHLLSVPEVRCARHGNSLYLAEGSGAIMSLLELHVPHETIYYNTLFSNEMNPPQRHFGPTPTQFLNSVVYRNLQAEVTCKDGFVQEFRPLWRENTEESDLTSDKAVGYITSAVPYRSVSLLHCDIEIPPGSNQSLLDQLAINLSLIAMHSVREGGVVIIKVLYAMGYYFHLLMNLFAPCSTKGYILSNGYACRGDMECYLVFVMGYLGGPTFVHEVVRMAKTLVQRHGTLLSKSDEITLTRLFTSQRQRVTDILSSPLPRLIKYLRKNIDTALIEAGGQPVRPFCAESLVSTLANITQITQIIASHIDTVIRSVIYMEAEGDLADTVFLFTPYNLSTDGKKRTSLKQCTRQILEVTILGLRVENLNKIGDIISLVLKGMISMEDLIPLRTYLKHSTCPKYLKAVLGITKLKEMFTDTSVLYLTRAQQKFYMKTIGNAVKGYYSNCDS
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: NADE_METB6
Sequence: MAQELGCRMGQVEQMIRYAYWNSKSQGIVVGVSGGVDSALAAAFCCRAIGPEKVLGLSLPASVSNPQDLSDAQELCAMLGMEHRVVLIDPMLAAFKTIPGFVETPYLLGNLMARIRMTVLYYHANRDHRLVCGTSNRSEAMLGYCTKYGDNAADFQPIVHLYKTDVYEMAKEVKIPKAILEKTPSAGLWAGQSDEGEIGLSYAEIDAALKNLEANGWKAGTPSEEKVLSRAQANAHKRLAAPNLLSVP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: IMA2_CAEEL
Sequence: MTLTETSLSHNAEEGKDEGGRLQQYKNLTKHEELRRRRTECSVEIRKQKGADMMMKRRNIVDVDEGGNSESELEEPEKISHQQSSTRLSNDEIRAILSNNPSEDDMVRCFESLRKSLSKTKNPPIDEVIHCGLLQALVQALSVENERVQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWAVANIAGDSSQLRDYVIKCHGVEALMHLMEKVDQLGDSHVRTIAWAFSNMCRHKNPHAPLEVLRVLSKGLVKLVQHTDRQVRQDACWAVSYLTDGPDEQIELARESGVLPHVVAFFKEAENLVAPALRTLGNVATGNDSLTQAVIDLGSLDEILPLMEKTRSSSIVKECCWLVSNIIAGTQKQIQAVLDANLLPVLINVLKSGDHKCQFEASWALSNLAQGGTNRQVVAMLEDNVVPALCQALLQTNTDMLNNTLETLYTLMLTVQNGYPHKVDILHDQVEENGGLDSLERLQESQSEQIYTQAYRIITQFFTDDDAGEKESHENADPQDNKWSF
What is the function of this protein?
Nuclear transport receptor that mediates nuclear import of proteins, and which is involved in sister chromatid cohesion (PubMed:11311162, PubMed:12221121, PubMed:30563860).  Binds specifically and directly to substrates containing either a simple or bipartite nuclear localization signals (NLS) motif (By similarity).  Promotes docking of import substrates to the nuclear envelope (By similarity).  Together with akir-1 adapter, required for the import and load of cohesin complex proteins in meiotic nuclei (PubMed:30563860).
What are the official names of this protein?
Importin subunit alpha-2, Karyopherin subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus envelope. Note=In interphase germ cells and embryonic cells, localizes to the cytoplasm and nuclear envelope, whereas in developing oocytes, it localizes in the cytoplasm and nucleus.
Protein: FBK13_ARATH
Sequence: MRRRRCDLQPKRTRMCDLQPKRTSMCDLPPKLVGEKILTRIPITSLRAVRSTCKLWNALTKDRVLGKAAAQFLGFMTMDSKVCSVRFHLRRSKEEEEDTMDLSIKQVDLLNQVEISRVYHCDGLLLCVAKDNSRVVVWNPYLGQTRWIRPRTESNIGDSYALGYDINRNHKILRMVQTRNVSVYRYEIYDLRSNSWRVLEVTPNGEMDPNHPLYGVSVKGNTYFFAHEDSSSGEIDEDGDIIDLEDFLLCFDFTTETFGLRLPLPFHSTIDATVTLSCVRDQQLAVLYHNEGLHSDDRFTTVEFWVTTSIEPNSVSWSKFLTVDMRPLALTGVRFDNDMGATFFIDEDEKVAVVFDLDGYLSTESARYHTAFISGKDGFFKPVTLGVAPNVGEPCPRTGHIPTTYRPPLVCSSTYLPSLVQVNQQRKRKERHV
What are the official names of this protein?
F-box/kelch-repeat protein At1g25150.
Protein: PYRC_AGRRK
Sequence: MQKLTIRRPDDWHLHLRDGAMLEGVIGDTSRHFARAIIMPNLVPPVVTTADATAYRERILKALPAGDRFQPLMTLYLTEHTNPDDVEEGKKSGLITAVKLYPAGATTNSHGGVRNLDKAMPTLERMAKIGLPLCVHGEVTTPEVDIFDREAVFIETVLDPLRQRLPELKVTMEHVTTSDGIDYIKSAKANLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRESHRLALRAAATSGDSRFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEQDGALDKLEAFASLNGPAWYGLAPNEERITLIRRVESVTFPEKIETGAGTVTVFDPMFPLHWDVEG
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: HRD1A_ARATH
Sequence: MIRLRTYAGLSFMATLAVIYHAFSSRGQFYPATVYLSTSKISLVLLLNMCLVLMLSLWHLVKFVFLGSLREAEVERLNEQAWRELMEILFAITIFRQDFSSGFLPLVVTLLLIKALHWLAQKRVEYIETTPSVSKLSHFRIVSFMGFLLLVDSLFMYSSIRHLIQSRQASVSLFFSFEYMILATTTVAIFVKYVFYVTDMLMDGQWEKKPVYTFYLELIRDLLHLSMYICFFFVIFMNYGVPLHLLRELYETFRNFQIRVSDYLRYRKITSNMNDRFPDATPEELTASDATCIICREEMTNAKKLICGHLFHVHCLRSWLERQQTCPTCRALVVPPENATSAAPGQRELHQGSQQGTSSSGNQGSEISSSAGVSNNSLSRHHARLQAAASAASVYGKSMVYPSANTVAWSSGVPGTEQVSTEPDQTLPQHNLPVENSHAYANMSETKLEEMRKSLETHLEILRNRLHFLETRKPESAGEPENKGKSVADAAE
What is the function of this protein?
Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD).  Targets the misfolded LRR receptor kinase BRI1.  Functions redundantly with HRD3B.
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase HRD1A, AtHrd1A, RING-type E3 ubiquitin transferase HRD1A.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PGK_RHOPA
Sequence: MTKTFRTLDDVDVKGKRVLLRVDLNVPMDAGKVTDTTRLERVMPTITELSGKGAKVILLAHFGRPKGRDDKNSLKPVAAALADVIKKPVGFADDCIGEPAAKAIAAMADGDILCLENTRFHPEEEKNDPAFVAKLAELGDIWVNDAFSAAHRAHATTEGLGHKLPAYAGRTMQAELVALNKALEAPVKPVIAIVGGAKVSTKIDLLENLVTKVQALVIGGGMANTFLHAQGVKVGKSLCEKDLAPTALRILDKAEAANCAIILPVDATVAYHFEANAPSFAYGLDAIPDDAMILDVGPRSIERIHAAIDDAATLVWNGPVGAFELTPFDKGTVEAAKHAAKRTKAGKLVSVAGGGDTVAALNHAGVADDFTYISTAGGAFLEWMEGKPLPGVEVLQVK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_PARP8
Sequence: MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQLGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRDHVPTQSWT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_YERPS
Sequence: MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_PARD8
Sequence: MAKKTVAAKKRNVKVDAYGQAHIHSSFNNIIVSLANSEGQVISWSSAGKMGFRSSKKNTPYAAQMAAQDCAKVAYDLGLRKVKVFVKGPGNGRESAIRTIHGAGIEVTEIVDVTPLPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NRDR_SHEFN
Sequence: MHCPFCSATDTKVIDSRLVADGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLRGGMLRAVEKRPVSIDEIEQALTKIKSTLRATGEREVNSEMIGNLMMEQLMSLDKVAYIRFASVYRAFEDVSQFGEAIAKLQK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YBEY_CHRSD
Sequence: MTPDIDRQVALETATELLPTQADLEAWVGAVLARHPDTDRHELSVRFVTADESQALNRDYRGKDKPTNVLSFPFEAPPGLPLALLGDLAICHAVVVDEAAEQGKPLAHHYAHMVIHGTLHLLGYDHIDDREAEEMEALERELLAHFAIGDPYAE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UHPB_SALTY
Sequence: MNTFFSRLITVVACFFIFSAAWFCLWSISLHLVERPELAALLFPFGLRLGLMLQCPRGYWPVLLGAEWLLVYWLAQEVALAHLPLLMIGSVLTLLPVALTSRYRHQRDWRTLLLQGAALTAAALLQSLPWLGQGEEAWNALLLTLTGGLTLAPICLVFWHYLTSTTWLPLGPSLVSQPVNWRGRHLIWYLLLFIVSLWLQLGLPAELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWHDHPVDLLLSLLAQSLTGLLLGAGIQRLRELNQSLQKELARNHRLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNGGVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLAQAIRSLLREMELESRGIVSHLDWRIDETALSESQRVTLFRVCQEGLNNIVKHANASAVTLQGWQQDERLMLVIEDDGSGLPPGSHQQGFGLTGMRERVSALGGTLTISCTHGTRVSVSLPQRYV
What is the function of this protein?
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT.  UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA.  Can also dephosphorylate UhpA.
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase UhpB.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECO_BARBK
Sequence: MKWKEQAIILGARQYGETSVILEVVTRQHGRYMGVVKGGRSRRMAALLQPGNFVEAEWWARLDEHLGLFKLEALDLCASRLMFLPEALYGLQLMASHFRLLPERDPHPILYDILHLFMQNFDEQFVNAELLVRFEMRLLEELGFGLDLSHCAVTGRQEKLYYVSPKSGRAVCEEVGLPWKNKLLLLPKFLIERTNRPVDFDDIRNGFTLTDFFLTRHVWEPRGIKQPSVRAILIQLFERRFHTKA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ATP25_AJECG
Sequence: MSRVLLRGIQCHACRSNVIRSFISLSDVAITPLAGGSRSTAQARPPPLSRNFSSQHAKLFSNQPSDNAELSVDPIPEIHNGEEPEGQPEESQEHIPWYLKEEQVEETIPHPLRRQQPLPPLPENPPPILENLLEHISVDIGLDNLSLLDLRRLDPPPALGANLIMIFGTARGVKHLNVSADRLCRWLRTTYKLRPDADGLLGRNELKIKLRRKARRAKLAKSAKSTLTQPDDGITTGWICVDVGTVEGGQFRKPEEELRKVGFVGFGTVVEGTRIVVQMMTEEKREEIDLEGLWRQKLERNSLENEGLPQPQAAAPQEAGDIHEQLTIPPTNINHQISHATQISPNYEQRRGISTGSRYQDATSDTWGTSRISPNGETTHLEPSAPSSPTSLSHRFKNIPPHEAIYDLGQGTHDRCSTAFLQQFYQEVARAPSELASSRRIELMCIAIELHHPGYRKPDLFQAIQEHILSNYALTRAQFLQILDAFLSFKPDLTSNPPRLLLPNADMELALQIIDHAGLRGLNLLDSTILVKLFVGVSFRAQVYPVEQKDLPNSPVIGNRIPVPLNTCDAVKRVQSRLTRVKTAAKISFTAEQYMKILRVLFDQGSYSGFWNTWEDMALAGVARDKALYVFLFQLHAESDGWQCFTTQLLNCIPMMERENPPVHLDGELAEVTQKCITIAYPEIIDRVERNEQNPLVRMWHRCRVAIENAAAAGGRGQDSTAPYVCNHSDI
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1076_STAHJ
Sequence: MSQNNNETMIADIRKKLNIVNQGLLNPDKFKNANQQDIEEIHNFVMSKDSFSPSEVTAIADELGNLRQD
What are the official names of this protein?
UPF0435 protein SH1076.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: RPAP1_HUMAN
Sequence: MLSRPKPGESEVDLLHFQSQFLAAGAAPAVQLVKKGNRGGGDANSDRPPLQDHRDVVMLDNLPDLPPALVPSPPKRARPSPGHCLPEDEDPEERLRRHDQHITAVLTKIIERDTSSVAVNLPVPSGVAFPAVFLRSRDTQGKSATSGKRSIFAQEIAARRIAEAKGPSVGEVVPNVGPPEGAVTCETPTPRNQGCQLPGSSHSFQGPNLVTGKGLRDQEAEQEAQTIHEENIARLQAMAPEEILQEQQRLLAQLDPSLVAFLRSHSHTQEQTGETASEEQRPGGPSANVTKEEPLMSAFASEPRKRDKLEPEAPALALPVTPQKEWLHMDTVELEKLHWTQDLPPVRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLAQVISRAQAGEFGDRLAGSVLSLLLDAGFLFLLRFSLDDRVDGVIATAIRALRALLVAPGDEELLDSTFSWYHGALTFPLMPSQEDKEDEDEDEECPAGKAKRKSPEEESRPPPDLARHDVIKGLLATSLLPRLRYVLEVTYPGPAVVLDILAVLIRLARHSLESATRVLECPRLIETIVREFLPTSWSPVGAGPTPSLYKVPCATAMKLLRVLASAGRNIAARLLSSFDLRSRLCRIIAEAPQELALPPEEAEMLSTEALRLWAVAASYGQGGYLYRELYPVLMRALQVVPRELSTHPPQPLSMQRIASLLTLLTQLTLAAGSTPAETISDSAEASLSATPSLVTWTQVSGLQPLVEPCLRQTLKLLSRPEMWRAVGPVPVACLLFLGAYYQAWSQQPSSCPEDWLQDMQRLSEELLLPLLSQPTLGSLWDSLRHCSLLCNPLSCVPALEAPPSLVSLGCSGGCPRLSLAGSASPFPFLTALLSLLNTLAQIHKGLCGQLAAILAAPGLQNYFLQCVAPGAAPHLTPFSAWALRHEYHLQYLALALAQKAAALQPLPATHAALYHGMALALLSRLLPGSEYLTHELLLSCVFRLEFLPERTSGGPEAADFSDQLSLGSSRVPRCGQGTLLAQACQDLPSIRNCYLTHCSPARASLLASQALHRGELQRVPTLLLPMPTEPLLPTDWPFLPLIRLYHRASDTPSGLSPTDTMGTAMRVLQWVLVLESWRPQALWAVPPAARLARLMCVFLVDSELFRESPVQHLVAALLAQLCQPQVLPNLNLDCRLPGLTSFPDLYANFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGALRALSLPLTQLPVSLECYTVPPEDNLALLQLYFRTLVTGALRPRWCPVLYAVAVAHVNSFIFSQDPQSSDEVKAARRSMLQKTWLLADEGLRQHLLHYKLPNSTLPEGFELYSQLPPLRQHYLQRLTSTVLQNGVSET
What is the function of this protein?
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.  Required for interaction of the RNA polymerase II complex with acetylated histone H3.
What are the official names of this protein?
RNA polymerase II-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the RPAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSB_STRM5
Sequence: MTEFVVAIPARYAASRLPGKPLRLLGGEPLVLHVARRALQAGAGEVWVATDDQRIADALSGLAEVKVAMTAASHASGTDRLAECARIAGWADDTVVVNLQGDEPFAPAAGIRAVAEALVGGNAPMSTLATTVEDAHTLFDPNVVKLVRNVRNEAMYFSRAPIAWHRDGFARSRDTLPAGHNWLRHIGIYGYRAGFLQQFAAMPPGQLEQVESLEQLRVLEAGFPISVAISPEPFPPGIDTPEDLERAEVLLQAMAAR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP20_ORYSJ
Sequence: MAAEAETKAMITLRSCEGQVFEVAEAVAMESQTIRHMIEDKCADTGIPLPNVSAKILSKVIEYCSKHVEARGGAAAAADGDAPAPAAVEANKAVEDELKTFDAEFVKVDQSTLFDLILAANYLNIKGLLDLTCQTVADMIKGKTPEEIRKTFNIKNDFTPEEEEEVRRENQWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, a RING-box and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
What are the official names of this protein?
SKP1-like protein 20, SKP1-like 20.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OXYR_PIG
Sequence: MEGVLAANWSAEAVNSSAAPPEAEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRALRRPADRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAEAAEAIAGTEGAAAGSRGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDADAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSSSHLKTSRPGETSVSKKSNSSTFVLSQHSSSQKSCS
What is the function of this protein?
Receptor for oxytocin.  The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Oxytocin receptor, OT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANK2_HUMAN
Sequence: MRRLGPFHPRVHWAAPPSLSSGLHRLLFLRGTRIPSSTTLSPPRHDSLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAAEEARRNPTLGGLLGRQRLLLRMGGGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQEPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLCGRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP
What is the function of this protein?
Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.
What are the official names of this protein?
Pantothenate kinase 2, mitochondrial, hPanK2, Pantothenic acid kinase 2.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. Mitochondrion intermembrane space. Nucleus. Note=Localizes predominantly to the mitochondria and to a lesser extent to the nucleus. Found in both the mitochondria and the nucleus throughout the cell cycle, with the exception of the G2/M phase when it is restricted to mitochdondria. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm.