PharMolix/UniProtQA huggingface dataset:
Protein: NADK2_SYNY3
Sequence: MPKVGIIFNDDKPTACSVAQELQEQLQQSGFTVAMETGSGGLLGYSQPDRPICHTRIEHLTPPHFDESMPFAIVLGGDGTVLSAFRQLAPLGIPLLTINTGHMGFLTEIYLNQLPTAIEQLINGDYQIESRSMMTVRLMREENLLWEALSLNEMVLHREPLTSMCHFEIQVGYHASVDIAADGIIVSTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDLEPVTIFPATPNRMVLVVDGNGGCYVLPEDRVHLSKSPYPAKFIRLQTPEFFRILREKLGWGLPHIAKPTSVELP
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (PubMed:22056937, PubMed:30693583).  Functions as a growth repressor under light-activated heterotrophic growth conditions and light and dark cycle conditions in the presence of glucose (PubMed:33560438).  NADP(H)/NAD(H) maintenance by slr0400 probably plays a significant role in modulating glycolysis and the TCA cycle to repress the growth rate and maintain the photosynthetic capacity (PubMed:33560438).
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_ACIBC
Sequence: MNQEVKSGKVLSPSTPWTQRPVPGIEVADEQQTLKATFTEPTIECPECHALVTRTAISFNAYVCPQCDEHLRMKARDRLNWFFDNVVAELGQEFSAKDPLKFVDSKPYPDRMREAQTKTGETEALIAMQGNLNGVDMIACAFEFDFMGGSMGTVVGDRFVKAAELAIEKRQPLICFAASGGARMQEGMLSLMQMARTSAAIQKLKDAGLPYIVVLTHPVYGGVTASLAMLGDIHIAEPKAMIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRLVSKLMNLP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPR_GIBZE
Sequence: MASATRQFARAATRATRNGFAIAPRQVIRQQGRRYYSSEPAQKSSSAWIWLTGAAVAGGAGYYFYGNSASSATAKVFNPSKEDYQKVYNEIAARLEEKDDYDDGSYGPVLVRLAWHASGTYDKETGTGGSNGATMRFAPESDHGANAGLAAARDFLQPVKEKFPWITYSDLWILAGVCAIQEMLGPAIPYRPGRSDRDVSGCTPDGRLPDASKRQDHLRGIFGRMGFNDQEIVALSGAHALGRCHTDRSGYSGPWTFSPTVLTNDYFRLLVEEKWQWKKWNGPAQYEDKSTKSLMMLPSDIALIEDKKFKPWVEKYAKDNDAFFKDFSNVVLRLFELGVPFAQGTENQRWTFKPTHQE
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Cytochrome c peroxidase, mitochondrial, CCP.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL25_AGRFC
Sequence: MSKESYELKAEARERVGKGSSRELRRNGLIPAVIYGDKQAPISIALSTNEVTKRIHAGGFMTTVGTIDVDGKKIKVLPKDYQLDPVRDFTMHVDFLRVSGNTLVNVEIPVHFENEEKSDIKIGGVLNIVRHTVEFHCPANDIPEAITVDLSGLKIGDSVHISNVKLPKNITPVIADRDFTIATIVAPAAGVEEETTEEASEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: UVRC_CLOBH
Sequence: MFDLEYQLKNLPDKPGVYLMKNNLGEIIYVGKAKILKNRVRQYFQKSQKHSEKVKAMVKNIEEFEYIITDSEIEALILECNLIKKYRPKYNILLKDDKHYPFIKVTLAEDFPRVISTRKVTKDGSKYFGPYVDGSSVKDIIELIKKTFPIRTCKKNIVEEAKAIRPCLNYQIGLCKAPCAQYIKKSEYRETIDDVIKLLSGKHLDIVENFKLNMEKAAENLEFEKAAMLRDKINIIEKIGEKQKIILNNFDNEDYISLYSDGKDTCFQVFFLRNGKIVGREHFIIEDTFDTNSSTLISNFLKEFYGGTAYIPKTIYVPNIEDEALLEQWLTLKKESKSTIKIPIKGEKKNILVLVEKNAKTTLENFKLKYLQEKALYDNVLKDLKNILRLQEEPIRIEAFDISNIQGFDSVGSMVVFEKGRAKPSDYRRFKINTVKGADDYKSMKEILTRRFQHGLSEIKSIQDRKLEFSSGKFSVFPDLILMDGGKGQINIALEVLNAFNIDIPVCGMVKDNKHRTRGLIYNGEEIIINKYGSVMKFITRVQDEVHRFAISYHRSLRGKNSFHSLLDDIPNIGEKRKKDLLFNFKSIDNIKKATYEELLSIPSMDKKSAECVLEFFK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB9_AGRT9
Sequence: MTRKALFILACLFAAATGAEAEDTPMAGKLDPRMRYLAYNPDQVVRLSTAVGATLVVTFATNETVTSVAVSNSKDLAALPRGNYLFFKASQVLTPQPVIVLTASDSGMRRYVFSISSKTLSHLDKEQPDLYYSVQFAYPADDAAARRREAQQRAVVDRLHAEAQYQRKAEDLLDQPVTALGATDSNWHYVAQGDRSLLPLEVFDNGFTTVFHFPGNVRIPSIYTINPDGKEAVANYSVKGSDVEISSVSRGWRLRDGHTVLCIWNAAYDPVGQRPQTGTVRPDVKRVLKGAKG
What is the function of this protein?
Is essential for the biogenesis of the T-pilus, which is required for virulence and T-DNA transfer to plant cells.  When is associated with virB7, might function as a nucleation center for recruitment of VirB proteins during assembly of the T-DNA transfer machine (By similarity).
What are the official names of this protein?
Protein virB9.
What is the protein family that this protein belongs to?
Belongs to the TrbG/VirB9 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIS7_POLAQ
Sequence: MRQADVTRNTSETKIQISINLDGTGKAELASGVPFLDHMLDQIARHGMIDLKVVAQGDTHIDDHHTVEDVGITLGQAFAKAVGDKAGITRYGHSYVPLDETLSRVVVDFSGRPGLEFNVPFTRARVGDFDVDLSIEFFRGFVNHAGVTLHIDNLRGINAHHQIETVFKAFGRALRMALTVDPRAAGVVPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE32_BRUAB
Sequence: MHLTPREFDKLVIHMLSDVALKRKNKGLKLNHPEAVAVLSAYVLDGAREGKTVEEVMDGARSVLKADDVMDGVPDLLPLIQVEAVFSDGSRLVSLHNPIT
What are the official names of this protein?
Urease subunit gamma 2, Urea amidohydrolase subunit gamma 2.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ALCBS
Sequence: MNRTPLVAGNWKMNGRKDLLTEMADALAGYAGAAEVVICPPFPYLAAARSAMPGAVGIGSQNVSEQEDGAFTGEVSAPMLAEVGCGYVIIGHSERRALYGETDAQIASKFAHAQAAGLVPILCVGETLEERDSGNTDTIVCGQLRAVVDAVGVAAFANAIVAYEPVWAIGTGKTASPEQAQAVHACLRQFLAKDDPDIAQSLRLLYGGSVKADNAALLFAQSDIDGGLIGGASLTADSFIAICQAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_STACT
Sequence: MLKIGPYEMESRLLLGTGKFDNEEIQTKAIEASGTDVLTFAVRRMNLYDKNLPNPLANVNLKDFVTFPNTAGAKTVDEAIRIAEIAKHAGVCDMIKVEIIGDDETLLPDPIATYEACEILLERGYIVCPYIAEDVVLAKRLEELGVHAVMPLASPIGTGRGINNPLNLSYIVKNANVPIIVDAGIGSAKDAAEAMELGADAVLLNSAVSRAKDPVKMAEAMKLGIEAGRLSYEAGRIPVKYTAQASSPSEGLGFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_FRAP2
Sequence: MSRVKRGVTARARHKKVLKQAKGYYGARSRVYRVAKQAVIKAGQYAYRDRKVKKRTFRSLWIVRINAAARQHDISYSQLINGLNKAGVELDRKALAELAVYNKDAFAAVVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DCUP_XANOR
Sequence: MLKNDRLLRALNRQPVDRTPVWLMRQAGRYLPEYRATRARAGSFLSMAKNPDIACEVTLQPLQRFPLDAAILFSDILTIPDAMGLELYFVEGEGPKFRHPVRDAAAIHRLGVPDMETELRYVMDAVRVIRRELDGSVPLIGFSGSPWTLACYMIEGGGSKEYARIKAMAFNAPEVLHHLLGTVTDAVIAYLAAQRAAGAQALQVFDTWGGVLSPAMYHEFSLPYLTRIAHELERGEGAERTPLVLFGKGNGAYVADLAASGAEAVGVDWTISLADAAQRAGGRVALQGNLDPATLYGSPEAIRTEVGKTLDSYAQGNGGSREGHVLNLGHGMSPDMNPEHVGVLVEAVQRLSKR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F17EG_ECOLX
Sequence: MTNFYKVFLAVFILVCCNISHAAVSFIGSTENDVGPSQSSYSRTHAMDNLPFVYNTGYNIGYQNANVWRISGGFCVGLDGKVDLPVVGSLDGQSIYGLTEEVGLLIWMGDTNYSRGTAMSGNSWENVFSGWCVGNYVSTQGLSVHVRPVILKRNSSAQYSVQKTSIGSIRMRPYNGSSAGSVQTTVNFSLNPFTLNDTVTSCRLLTPSAVNVSLAAISAGQLPSSGDEVVAGTTSLKLQCDAGVTVWATLTDATTPSNRSDILTLTGASTATGVGLRIYKNTDSTPLKFGPDSPVKGNENQWQLSTGTETSPSVRLYVKYVNTGEGINPGTVNGISTFTFSYQ
What is the function of this protein?
Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia.  Also confers adhesiveness to laminin and basement membranes (By similarity).
What are the official names of this protein?
F17e-G fimbrial adhesin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium. Note=Attached to the tip of the fimbrial filaments.
Protein: CYB_TAMQA
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGILLLILVLMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPILHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPAISLFENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL22_EXIS2
Sequence: MQSKASANMVRIAPRKARLVVDLIRGKQIGEALSILAYTNKAATPIVEKVLKSAIANAEHNFDMNIENLVVTEAYVNEGPTLKRFRPRAMGRASRINKRTSHVHIVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL1_BRASB
Sequence: MAIGKRLKKAREGIDRTKLYPLADAIKMIKERAVSKFDETIEVAINLGVDPRHADQMVRGVVMLPNGTGRTLRVGVFARGAKAEEAKAAGADVVGAEDLVEKVQNGNIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKIGTVTMDVAGAVKGAKGGSVEFRVEKAGIIQAGVGKASFAEDKLVENIKALADAVVKAKPAGAKGTYVQRVAVSSTMGPGVKVEPGTVLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FEM1A_DROME
Sequence: MDYKFIVFNAARDNNLAQLKATLYNKSSVEVGSLISAKVNGATPLVISCRNGHYDIVEYLLTKCRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGHYEIVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGATMDVDYYGMTPLLAASVTGHMPIVEHLITLPCVSRESRIHALELLGATYVDRKRDMAAALNLWRRALEERAVEPPLEKKVQEPVPAYEMVREVTSVEELEEMVLDPDEMRMQALVIRQRILGPTHPDTSYYIRFRGAHYADAGRFDRCIELWSYALTMQQKILQPLSPMTQSSLLSFAELFSFMLVEAGRLLPRGRVVPPIEPDSMLTIFYKAVKEVERGLAFTLEQQKDQQHPQKQLPAADKSPSCSASSSASSSSSTTLLSAHQHDCNHDPNALSRTMISAIHIGCLLSSLLDTDALSPEMRRQVMGALYRLNRLKVRVRFDRTALHYACYREGTLAGRYPSCQFPSVTLAKALLEVGADPNAIDEAGNTPLHLATMQPYVEPLSHILLEGGAHLDTKNYAGETFESLLAPTPMHKIIDPMKYTTLACLAARTIKKHDIRYEGTVPATLYEFIELH
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.
What are the official names of this protein?
Protein fem-1 homolog CG6966.
What is the protein family that this protein belongs to?
Belongs to the fem-1 family.
Protein: Y4CJ_SINFN
Sequence: MARKNLLAGLVDTAEIPHADVAPAYPMRGASKSMVRSLDELSRQAEKFLEGETVVELDPETLDGSFVSDRMGDSSEQFEELKQAIAERGQDTPILVRPHPSAADRYQIVFGHRRARVARELGRKVKAVVKALDDRTHVIAQGQENSARANLSFIERANFASHLEKLGYDRTIIGSALAANAAAISKMIAVIDRIPEETIARIGPCPAVGRERWVELSLLVGKTANEAKVKAIVSDPSFNELSTDDRFNSLFSGLNSAAKPVRKTTPKILENWQPADKTVSAKYSNSAKAFALSMKSRNAGPFGRYIADNLDRLYAEFLEQGNRKED
What are the official names of this protein?
Putative replication protein B.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: IHFA_BUCCC
Sequence: MVLTKAEISDYLFHKLELSKQNIKDLVEIFFEEVRKSLELGESVKLSGFGNFYLRDKKQRPGRNPKTGEYIPISARRVVVFKPGQKLRSRVESFKDIKKEKDIV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LPDA_MYCTO
Sequence: MVTRIVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTELRRAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDSTPGLARHRIKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDALPDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRLFKNARAASVTRTGAGVLVTMTDGRTVEGSHALMTIGSVPNTSGLGLERVGIQLGRGNYLTVDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALGEGVSPIRLRTVAATVFTRPEIAAVGVPQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRSTGVVIGGVVVAPIASELILPIAVAVQNRITVNELAQTLAVYPSLSGSITEAARRLMAHDDLDCTAAQDAAEQLALVPHHLPTSN
What is the function of this protein?
May contribute to virulence by increasing resistance to reactive oxygen intermediates.  It can reduce 2,6-dimethyl-1,4-benzoquinone (DMBQ), 5-hydroxy-1,4-naphthaquinone (5-HNQ) and menadione (By similarity).
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), NAD(P)H quinone reductase, NAD(P)H: menadione oxidoreductase, NADH-menadione reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: EX7L_XANCB
Sequence: MADRTEQILTPSQLNTLARDLLEGSFPLVWVEAELGNVTRPASGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFEELRARLAAEGVFDAERKQPLPAHVRRLAVITSPSGAAVRDVLSVLARRFPLLEVDILPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAHTPVVSAVGHETDVSLSDFAADVRAPTPSVAAELLVPDQRELVARVRRAQARLSQLQQHTLGQAMQHADRLALRLRARSPQARPQLLQRRQEDAARHLRARMQHILERLQARVQRAQAGVQSHSPQRHLAPLQQRLRAAHPQAAMQRRLQQDHLHLRGLVRSLEAVSPLATVARGYAIVTRQADGSVVRSAAELTQGDRLRAQLADGSVTVVVDTSETG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPA_SYNY3
Sequence: MVNSAVRSLAIVGGVHGNERTGVEVVRRWQQKDFARYFPALKCHYFLANPRAIAANRRYINQDLNRCFRPQDRKNPYLMGYEQLRARQLAHQISLAGIDFIVDLHTTTAAMGTTLILNCPHPLLLNLAAYLSAQDEEIRVLQYSPQKDLPYIRGLCELGLTIELGPVPQGVYDPTAIAKTQRTLARILAYLQASTSGNVPAADNCTVYQQIDTIDYPRDEQGQIVAEIAPHIRDYQAIKPGTPLFYHRRGNVTPYQGAATVYPVFIGEAAYVEKGIAMALTQRKTIAI
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: EX7S_VESOH
Sequence: MSEKFNFNQGLIDLEKIVKAMESGDLSLEDSLNHFSKGVELTKQCQSALNKAEQKISMLTEQDNYTNEKPLKRL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC61A_ASHGO
Sequence: MSGRLLDLFKPFEAFLPEVIAPERKVPYNQKLIWTAVSLLIFLVLGQIPLYGIVSSEGSDPLQWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNLESKQDRELFQIAQKVCAIVLTLGQAIVVVLTGNYGSVSNLGIAISLLLILQLVFASFIVLLLDELLIKGYGLGSGISLFTATNIAEQIFWKAFAPTTVNNGRGTEFEGAVVALFHLLSVRKDKKRALVEAFYRDYLPNMFQVLSTVFVFLFVLYLQGFRYELPVRSTRTRGQVGSYPIKLFYTSNTPIMLQSALTSNIFLTSQLLYQKFPNNPIVKMLGVWGTRSDAPYSPNAAISGLSYYIQPPFSFTEALLDPIKTVVYVTFVLGACAMFSRTWIDVSGTSPRDVSKQFKEQGLVINGRRETSVYRELKKVIPTAAAFGGATIGALSVGSDLLGTLGSGTSILMATTTIYGYYETAAKEGGFAKNLVAGFSEML
What is the function of this protein?
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER.  It is required for assembly of membrane and secretory proteins and is essential for cell growth.  It interacts with other membrane proteins required for protein translocation.  Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event.  A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
What are the official names of this protein?
Protein transport protein SEC61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MUTL_NITHX
Sequence: MPVRQLPETVVNRIAAGEVVERPASVVKELVENAIDAGAGRIDIFTDGGGRRRIGITDDGGGMTKADLALAVDRHATSKLDDEDLLRIRTLGFRGEALPSIGAVAKLGITTRHGSEPHAWSLTVEGGRKSAIVPAALTQGTRVEVSDLFYATPARLKFLKTDRTEAEAIREVVRRLAMARPDIAFTLAGEERAPVTWTAALPGAAGQLTRLGDILGADFRCSAIAVRAERDGVTVEGFAAAPSLTRANALGQYLFVNGRPVRDKLIIGAVRAAYSDYLPRDRHPVVALFVTTAPQEVDANVHPAKTEVRFRNAGLVRALIVHALKEGLAREGRRTAANSDGAVLTAFRPAAVPRPANWDWRQSPASPVGAGPWSGGATAAAFAAPGQTAFDVGAPSADVRSDPNPVADLIDRPLGAARTQIHETYIVTQTRDGLIVVDQHAAHERIVYEKLKAALERDGVQRQILLIPDIVELDEATVEKLIDRAPELEKFGLAIESFGPGAVAVRETPSLLGKTNAAALLRDLAEHMAEWDEALPLERRLMHVAATMACHGSVRAGRILKPEEMNALLREMEDTPNSGQCNHGRPTYVELKLADIEKLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: KCY_ALKCK
Sequence: MAKGFNVAIDGPAGAGKSTVAKKTAEKLGFLYIDTGAMYRAITFAALAEGIDLHDGKALGKLLEKSELRLESSNEGTAVFWNGADITAAIRTNEVNSNVSLVASHREVREGMTAMQQELAKSKNAVLDGRDIGTHVLPDANVKVFLTASVEERARRRHLEQLEKGLPSDFEQLKKDIAKRDELDSTRAIAPLKQAADAQVVDTTSMGIDEVVETILDLVKEHSRQ
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_NATTJ
Sequence: MGKECRDIVELKEKLGIYVDDKLLLQAVTHTSYAHEQKDVVDHNERLEFLGDAVLELAISETLYKKYPELPEGELTKLRAELVCELSLVKIAEKLDLGKYLRLGKGEDSTGGRDRRSTLADTVEALIGAVYLQTNYDQTKQLILDLFKDQLSHIDNQRIGDYKTMIQELVQDRYGDPPKYQIVKESGPDHDKSFVAEVQINNEVVGRGSGKSKKEAEQNAAHFAFQKLSK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.