PharMolix/UniProtQA huggingface dataset:
Protein: DPO4_ALKOO
Sequence: MNPVIFLVDMNAFFISCEMTRNSKLIGIPAAVAGNPQNRTGIVLAANYEARRFGVKTAMTLNNALKLCPTMTVVPPDHRFYRQKSSEVMNLLSKYTPIIEQSSIDEAWLDMTGTENLFGKPADAAKLIMEDIKENLGLWCSIGISEGKFLSKMASDMKKPLGITELWKRDIQTKLWPLSIKSMHGVGAKTYEKLHSLGIETIGDFANLKKDDAHQILGKFGLDLYHHAHGIDTTPVQVISPDDMKSIGRSTTLPEDLVDIEQLKYILLTLCEDIGRSARKHNKRGRTVNLTLKSSDFKVIHRQVTIKATFNTMEIYEAGYHLLKLHLNPKIPIRLIGVSISGFEDTSVPEQISIFNMDEFNKRDTIGNNRNEKIDMVMDSIRNKYGSDKISRASLIIK
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL2_ASHGO
Sequence: MIAHLIVALLAMPVQSFFFDFGGHQAQQQTQQTTSYEDSVLNSDCKGYVCPYTNECSRGPEECSCPFPRSQLRCVLPNKQVVCISKPATNDKKLNDVYDDTAKGPRARNKGVRDCGWVEAAYKGLV
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: NDUF7_CAEEL
Sequence: MSLRVQNILINSLRQYSKQILKPPGYASPEKTNHLKKFLVDKIRVSGPITVAEYMKTCVSAPLVGYYGQFSKDQKVFGAKGDFITSPELTQLFGEMIGVWVFHELANTGHKGSWQLVELGPGRAQLMNDVLNALAKFNDKDVSVHLVETSDALIDEQEKSLCIYTSKNSIDTPFIRKNKTRTGVNIYWYKSIDDIPDGFTVFIGNEFLDALPIHQFHKSGDSWNEVYVNLTKDGDLCFMKSKGENLHTKGLIPSAIRDDSSRVTWECSPESGTVVNQIVDRITTFGGFSLLVDYGHDGSRNTHSFRAYKNHKQVDTLENPGLADLTADVDFGYLSTLVKDRVVIYGPNEQREFLAQLGIEHRLRRLLQVCKDRKQQEQLIESYNMLMGDMGLKFKAWALFPKTLEFILEQRGGPAGFSAKKKTTEN
What is the function of this protein?
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
What are the official names of this protein?
Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial, NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 homolog, Protein midA homolog.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y4407_BURM7
Sequence: MSADSADSVPSPRSAFATTLQIVSVVSFTFICYLTIGLPLAVLPGFVHDELGFSAIVAGAAISVQYFATLASRPLAGRCADTLGPKRTVLRGLAACGASGALLLSAFAFARWPAASIGLLVASRLVLGIGESLVGTGAILWGIGRVGTAHNARVISWNGIATYGALAIGAPVGVAISHALIPAVLGMLVIALAALGYYLARLITPVPLVHGERMSYASVLTRVLPHGLGLALGSAGFGSIATFITLYYAARHWPNAALSLTVFGTLFIGARLLFANTIKTHGGFRVAIVSFAFECAGLLMLWLAPVPHVALVGAALTGFGFALIFPALGVEAVALVPPASRGAALSAYSVFLDLSLGITGPLAGYVAGAFGYPQVFLCAAVAAAAGVALSTVLYQRQARLSGSGAAA
What are the official names of this protein?
Uncharacterized MFS-type transporter BMA10247_1907.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPPS_YEAST
Sequence: MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLKGGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKFLLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAILEVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDYDGILQRNVPELRMEIHSNLAKYFGPAHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNRDGRETIVDLTKTMAELCAVNELSVSDITMDLVDSELKQLVGPEPDLLLYFGPSLDLQGFPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK
What is the function of this protein?
With SRT1 or RER2, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit NUS1, Nuclear undecaprenyl pyrophosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet. Nucleus membrane; Single-pass membrane protein.
Protein: CP074_MOUSE
Sequence: MTPAAHGCKRVAWCPSRPPASAPSAPQEAARRGDAMGLKPSCLKGFKMCVSSSNNNHDEAPVLNDKHLSVPNIIITPPTPTGMGLSRDSNKQVWMDELGSYQDDGELEPEA
What are the official names of this protein?
Uncharacterized protein C16orf74 homolog.
Protein: RL14_LISMF
Sequence: MIQQESRMKVADNSGAREVLTIKVLGGSGRKTANIGDVVVCTVKQATPGGVVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GUTQ_ECO57
Sequence: MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII
What is the function of this protein?
Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P).  It is also able of sustaining the biosynthetic pathway of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs) (By similarity).
What are the official names of this protein?
Arabinose 5-phosphate isomerase GutQ, API, G-API, Phosphosugar aldol-ketol isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: CCME_RHOCB
Sequence: MRNLKKTRRIQILLVAGGALVLSTALIGYGMRDGINFFRAPSQIVAEPPAAGEVFRLGGLVEAGTLVRGQGEEITFKVTDGGASVPVTFTGVLPDLFGEGKGMVGTGEMVEGTFVAREILAKHDENYMPKEVTEALKEQGVYRDPAQPEG
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SERC_ECOHS
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_MESH2
Sequence: MLQELSRLNVADNTGAKIVGVIRNLGGSVKKTSNIGDIVVVSVKKAIPNGMLKEGQVVKALIVRSTYGLRRKNGTHIKFDDNAVVIIKEDGTPRGTRVFGPIAREIREKGYLKIASLAQEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FES1_YARLI
Sequence: MDKLLAWSVKQQQEGTNEPPPDPKLLAQLFGAPDDAQLMVQAMVVITQPDNKLEDKEVAFDNFEMLVENLDNANMMKNLKLWEPLLAQLSSPHPSLQKLAAWVVATATQNNPKSQEALVEQGDAGIKKLVDLTSHDDPEVVVKSLFALASAIRNCDDAYKLFESADGLKKVVGHLKPDATAQVKSKTLGVLTGILESETDLMKPEEKRQVFDILVKELETDDHIPSLERSLHVLVLLNQKGFPFTPEETEQVKKAAKRVEGKLDEEDVKYNEDLKYVNNL
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRX4_CHICK
Sequence: MSYPQFGYPYSSAPQFLMSTNSLTPCCESGGRTLPESGPAAPAQTPVYCPVYESRLLATARHELNSAAALGVYGGPYGGPQGYGNYVTYGTEAPAFYSLNTLEAKDGGGSAHAGISPAAAYYPYEHSLSQYQYDRYGAMDGGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCSDEKRPYEEEEEEEEECSQEDAMKSEKAEEPTGKEEKELELSDLEDLDAAESESSECEMRRPFPHPHPHPLPGGGPPPRAAEPPAAAAEEEEEEAAERARGCLKPAAEECEAALLGARPRGCEAKLCFPQGQPLLEAKPRIWSLAHTATSLNQAEYPSCMLKRSGGSAAAAVSAPVSVMDRHQDSPVTNLRNWVDGVFHDPLFRHSTLNQALSNTTVSWATTKGAILETGALGRSVGNGANVLKGQLANLAHQDSSKEFLAFPKAGSKMFCS
What is the function of this protein?
Regulates the chamber-specific expression of myosin isoforms by activating the expression of the ventricle myosin heavy chain-1 (Vmhc1) and suppressing the expression of the atrial myosin heavy chain-1 (Amhc1) in the ventricles.  May play a critical role in establishing chamber-specific gene expression in the developing heart.
What are the official names of this protein?
Iroquois-class homeodomain protein IRX-4, Iroquois homeobox protein 4.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUB8_ARTBC
Sequence: MKGLLSLSVLPVLAYASPMIVDSIHQNAAPILSSTNAKDIPDSYIVVFKKGVTSTSALAHQNWVQDIHTSVESKRMKKRNQFTFKNEAFDGLKHTFDFAGGFLGYSGHFDEEVIEQVRRHPDVEYIERDSEVHTLKAATENGAPWGLARISHRDKLNFGTFNKYIYASQGGEGVDAYVIDTGTNIDHVDFEGRASWGKTIPQGDDDVDGNGHGTHCSGTIAGKKYGVAKKANVYAVKVLRTSGSGTMSDVVKGVQWAAESHLKSVGEAKKGNRKGFKGSVANMSLGGGKSVTLDRVVDQAVAVGMHFAVAAGNDNADACNYSPAGSKNSITVGASTLADERAYFSNFGKCTDIFAPGLNIQSTWIGSKHAVNTISGTSMASPHICGLLAYFLSLQPASDSAFAVAEITPAEMKDNMISIASKDLLSDIPSDTPNLLAWNGGGSDDYKKIIGGARENDTTEFSSTLTEKLEKLAEEGLTAIYNELKDAVVA
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAP1_RAT
Sequence: MAASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPAPQLDVTEANKEFMEQSEELYDALMDCHWQPLDTVSSEIPAMM
What is the function of this protein?
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins.  Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex.  May be involved in the methylation of tRNA(Sec).  Enhances efficiency of selenoproteins synthesis (By similarity).
What are the official names of this protein?
tRNA selenocysteine 1-associated protein 1, SECp43, tRNA selenocysteine-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM TRSPAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Abundant in the nucleus.
Protein: KAD_PARDP
Sequence: MAINIILLGPPGAGKGTQARRLIDERGLVQLSTGDMLREARSSGTEMGKRVAEVMDRGELVTDEIVIGLIREKLGQGGKGFIFDGFPRTLAQADALQALMAEMDQRIDAVIEMRVDDAALVSRISGRFTCGNCGEVYHDVTKPTKEPGKCDVCGSTDLRRRADDNEESLKTRLMEYYKKTSPLIGYYYVKGNLNPVDGLAEIDEVAAQVAKVMDKIPA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI13_DANRE
Sequence: MELLEEDLTCPICCCLFEDPRVLPCSHSFCKKCLEGILDGNRSPTWRPPFKCPTCRKETVHNGIASLQVNYSLRGIVEKYNRIRVMPRMSQCRVHSGQPLNIFCATDLKLICGFCATTGDHKGHKFCALEEAYEREKLAFEELFRVVEGWKGAEVHSCLESLESAKKKALERVSRDADRVSEYFDKLLRTLEHKRSEILSDLETLKLAVMQTFDPEINRLRSALEEQRRALNIAESFRSLSDPLTFLQQMQDFREKLRVIQGTPLPSRTDMDVSLSALQSFDVKEWDRVRLGQVDKLCAPYESSAYLSSLPPAAAPRFTRVMWRVVLVVCACLPALNFLPSDCLALSFQDKVVALGGFSLPSPGEIVRWLGFCWKEAASICTLLTELCRNCMLDLINTTSDFIS
What is the function of this protein?
E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD).  This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity).
What are the official names of this protein?
Tripartite motif-containing 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Also concentrates at the perinuclear endoplasmic reticulum.
Protein: MCE_ASFP4
Sequence: MASLDNLVARYQRCFNDQSLKNSTIELEIRFQQINFLLFKTVYEALVAQEIPSTISHSIRCIKKVHHENHCREKILPSENFYFKKQPLMFFKFSEPASLGCKVSLAIEQPIRKFILDSSVLVRLKNRTTFRVSELWKIELTIVKQLMGSEVSAKLTAFKTLLFDTPEQQTTKNMMSLINPDDEYLYEIEIEYTGKPESLTAADVIKIKNTVLTLISPNHLMLTAYHQAIEFIASHILSSEILLARIKSGKWGLKRLLPQVKSMTKADYMKFYPPVGYYITDKADGIRGIAVIQDTQIYVVADQLYSLGTTGIEPLKPTILDGEFMPEKKEFYGFDVIMYEGNLLTQQGFETRIETLSKGIKVLQAFNIKAEMKPFISLTSADPNVLLKNFESIFKKKTRPYSIDGIILVEPGNSYLNTNTFKWKPTWDNTLDFLVRKCPESLNVPEYAPKKGFSLHLLFVGISGELFKKLALNWCPGYTKLFPVTQRNQNYFPVQFQPSDFPLAFLYYHPDTSSFSDIDGKVLEMRCLKREINHVSWEIVKIREDRQQDLKTGGYFGNDFKTAELTWLNYMDPFSFEELAKGPSGMYFAGAKTGIYRAQTALISFIKQEIIQKISHQSWVIDLGIGKGQDLGRYLDAGVRHLVGIDKDQTALAELVYRKFSHATTRQHKHATNIYVLHQDLAEPAKEISEKVHQIYGFPKEGASSIVSNLFIHYLMKNTQQVENLAVLCHKLLQPGGMVWFTTMLGERVLELLHENRIELNEVWEARENEVVKFAIKRLFKEDILQETGQEIGVLLPFSNGDFYNEYLVNTAFLIKIFKHHGFSLVQKQSFKDWIPEFQNFSKSLYKILTEADKTWTSLFGFICLRKN
What is the function of this protein?
Probably catalyzes the second reaction in the mRNA cap formation pathway (By similarity).  Forms a covalent complex with GTP (By similarity).
What are the official names of this protein?
mRNA-capping enzyme, VTF/CE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: TARI2_STAAR
Sequence: MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNTQGINDDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDSYRALSSAQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: RSMH_ENDTX
Sequence: MFHIPVMPLETSRYLIGKPGGLYVDCTFGGGGHALYLLDKFKDIKIVAFDWDEDSSKRFIEREKEFSGRVTFIRDNFKNVKKALSALNISKVDGILADIGVSSKQFGDLDRGFSFNSGTLDMRMDKRNGFEAKEVVNSYSYEDLADIFYKYGEERKSRQIASAILLRRKRGIINTASELQTVICSVKRPEGRINPATKVFQALRIFVNSELENLAVLLSDAPELLNAGGRTVIISFHSLEDRIVKQNFKRNSECGIYKILTKKVVTALKEEVKINPGSRSARIRAAEKTSV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STREM
Sequence: MLDLKRIRTDFDAVAAKLKTRGVSEDTLTTLKALDEQRRALLVQTEELKAQRNIASAAIAQAKRQKKDASQQIADMQQLAANIKVIDAKLADIDQEITSIITVLPNTPHDSVPIGADEEDNVEIRRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTGARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTFELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPETSYDELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGLELIKPR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPF2_DROME
Sequence: MSLLRIRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKNDITPFDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKRYQAISEFKNEKIGACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMNILMRSYRILLKKSGQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGNTKGRVHLGKQQTGSIQTRRVKALRKTPEEKKENRQRKKVALKAAAAEALASQGNNPFSS
What is the function of this protein?
Required for normal assembly of the mitotic spindle.  May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs.
What are the official names of this protein?
Ribosome production factor 2 homolog, Brix domain-containing protein 1 homolog, Novel nucleolar protein 3, Ribosome biogenesis protein RPF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RPF2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Found in the nucleolus during interphase.
Protein: MYB96_ARATH
Sequence: MGRPPCCEKIGVKKGPWTPEEDIILVSYIQEHGPGNWRSVPTHTGLRRCSKSCRLRWTNYLRPGIKRGNFTEHEEKTIVHLQALLGNRWAAIASYLPERTDNDIKNYWNTHLKKKLKKINESGEEDNDGVSSSNTSSQKNHQSTNKGQWERRLQTDINMAKQALCEALSLDKPSSTLSSSSSLPTPVITQQNIRNFSSALLDRCYDPSSSSSSTTTTTTSNTTNPYPSGVYASSAENIARLLQDFMKDTPKALTLSSSSPVSETGPLTAAVSEEGGEGFEQSFFSFNSMDETQNLTQETSFFHDQVIKPEITMDQDHGLISQGSLSLFEKWLFDEQSHEMVGMALAGQEGMF
What is the function of this protein?
Transcription activator involved in the activation of cuticular wax biosynthesis under drought stress.  Binds directly to DNA consensus sequences found in the promoters of genes encoding very-long-chain fatty acid-condensing enzymes involved in cuticular wax biosynthesis (PubMed:21398568).  Functions together with MYB94 in the activation of cuticular wax biosynthesis (PubMed:27577115).  Involved in drought stress response through abscisic acid (ABA) signaling.  Mediates ABA signals that enhance plant resistance to drought by reducing stomatal opening.  Mediates ABA-auxin cross-talk to regulate lateral root growth under drought stress conditions (PubMed:19625633).  Involved in the regulation of ABA biosynthesis and ABA-dependent seed dormancy state.  Binds to the promoters of NCED2 and NCED6, which are enzymes catalyzing the first step of ABA biosynthesis (PubMed:25616734).  Regulates seed germination by controlling the expression of ABI4, a repressor of lipid breakdown during seed germination (PubMed:25869652).  Binds to the promoter of LTP3 and transactivates LTP3 gene in response to drought stress and freezing (PubMed:23404903).  Involved in cold stress response.  Binds directly to the promoters of heptahelical protein (HHP) genes in response to cold stress.  HHPs modulate the expression of SCRM/ICE1, SCRM2/ICE2 and CAMTA3, which are upstream regulators of cold-responsive C-repeat-binding factors (CBFs) (PubMed:25912720).  Involved in defense responses against the bacterial pathogen Pseudomonas syringae.  May act as a molecular link that mediates cross-talks between ABA and salicylate (PubMed:20149112).  Involved in a crosstalk between the circadian clock and ABA signaling.  Binds directly to the promoter of APRR1/TOC1 to activate its expression (PubMed:26725725).  Promotes ABA signaling (PubMed:30979883).  Recruits the histone deacetylase HDA15 to the promoters of a subset of Rho GTPase (ROP) genes, which repress ABA signaling at the early stages of signal transduction (PubMed:30979883).  HDA15 represses ROP expression by removing acetyl groups of histone H3 and H4 from the cognate regions, particularly in the presence of ABA (PubMed:30979883).
What are the official names of this protein?
Transcription factor MYB96, Myb-related protein 96, AtMYB96.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLGH_WIGBR
Sequence: MHYLRYFAIAFLLLLSSCSVTRHKPLIEGSTTTIPNTPSSNFINGSIFQQDNSLYYGYQPLFEDRRPKNIGDILTVLLQENVSASKSSSSNASRKSNANLEMNALPKIINKIIGNDQLSTDINSNNGFNGKGGSSAANTFSGTITVTVIDILTNGNLKVIGEKKISINQGTESIRFYGIVNPKTIDHNNQVMSNLISDSKIEYIGDGYINEVQKMNWLQRLFLNYFPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PSPC1_DANRE
Sequence: MANPNLKQVNIQNNATFPHQQNVTRSTESPGDPKETMEAVAPSPQDPSSANSEPQEMTVDIKNFRRPGEKTFTQRCRLFVGNLPSDMADEDFKKLFFKYGDAKEVFINRDRGFGFIRLETRTLAEIAKAELDGTVLGNRPIRIRFATHGAALTVRNLSPVVSNELLEQAFSQFGPVERAIVIVDDRGRPTGKGIVEFANKPAARKALDHCADGALLLTTSPRPVILEPTEQYDDEDGLPEKLLQKSAQYHKEREHKPHFAQPGTFEFEYSSRWKALDEMDKQQREQVERNIQEAKEKLETEMEAAKQEHQLMMMRQDLMRRQEELRRLEELRNQELQKRKQIELRHEEERRRREEDMIRHREQLDIRRQPDGFKSGFMESREQDMRMNEMGTRGAINIGDSFNPVTAISGNQGPTQMMGMGGRVGAMGPDGSSKMIPDNGVMPNERFSEGGPLQMGSPVGGQTGVDSPQPQQHSPMLVGAGSVPGVLGQSGFGRGSPVGGSFDGPNNKRRRY
What is the function of this protein?
Together with NONO, required for the formation of nuclear paraspeckles.  Acts as a coactivator during transcriptional activation.  Binds to RNA.  May act as a regulator the circadian clock (By similarity).
What are the official names of this protein?
Paraspeckle component 1.
What is the protein family that this protein belongs to?
Belongs to the PSPC family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Nucleus matrix. Nucleus speckle. Note=In punctate subnuclear structures localized adjacent to nuclear splicing speckles, called paraspeckles.