PharMolix/UniProtQA huggingface dataset:
Protein: REP_SLCV
Sequence: MPRNPNSFRLTARNIFLTYPRCDVPKEEVLEMLLHLSWSVVKPNYVRVAREEHSDGSPHLHCLIQLSGKSNIKDAGFFDLTHPRRSARFHPNIQAAKDTNAVKNYITKEGDYCESGQYKVSGGSKSNKDDVYHNAVNAGSAGEALDIIKAGDPKTFIVNYHNLLANVERLFQKPPEPWVPPFELSSFTSVPEELQDWADDYFNECSAAARPTSIIIEGGSRTGKTMWARSLGPHNYLSGHLDFNSRVFSNDVKYNVIDDVAPHYLKLKHWKELIGAQRDWQSNCKYGKPVQIKGGIPSIVLCNPGEGSSYKDFLDKAENSALREWTEKNAKFIFLEGPLYQSTAQDC
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SECB_BURP0
Sequence: MSDVENQPFFNIQRIYLKDLSLEQPNSPAIFLEQEMPAVEVEVDVKAERLAENVYEIVVAGTVTAKVREKVAFLVEAKQAGIFDIRNIPAEQIDPLCGIACPTILFPYLRSNIADSITRAGFPPIHLAEINFQALYEQRLAEISQQQQQGGAPNGTTLN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CHLL2
Sequence: MPEKLNTSARRATVTRTTKETDITATIDLDGSGTGNISSGVLFLDHMLTNFSRHSGIDITLDCKGDTEVDDHHSVEDIALVLGSAFLQSLGSKTGIQRYGWAMIPMDETLARCAVDLGGRSYCVFSAEFKRPAILGFSTEMVEHFFVSLSRTMQANIHLAIMEGKNTHHMIEAMFKAFAYAMKMAVAVTGKELPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_ACIAC
Sequence: MRGPQLSIHLIGLPGSGKSTVGRHLARRLGLPFIDSDHVIEQRIGGSIRGFFDREGEAAFRDLEEEVILELTEANVPPQVLATGGGVVIRPGNRTRLRERGTVVYLNASPEEIFRHIRHDQTRPLLQVGSPLDRLRELQRERDPLYREAAHFVISPERGKNVAALVQHIAMQLELAGIRPPSP
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUDD_ECOLI
Sequence: MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKATPLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQVPEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR
What is the function of this protein?
Catalyzes the dehydration of glucarate or L-idarate to 5-keto-4-deoxy-D-glucarate (5-kdGluc) (PubMed:9772162).  Also catalyzes the epimerization of D-glucarate and L-idarate (PubMed:11513584).
What are the official names of this protein?
Glucarate dehydratase, GDH, GlucD, D-glucarate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.
Protein: COAA_SHEB9
Sequence: MTSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSRLLNLIVKAKQQRGLVVDEFLGQKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQPHVKAPIYSHVTYDRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWYKERFLQFRSGAFSDKKSYFHHYSTLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLMRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_SULSY
Sequence: MTKEKIGVVLLNMGGPDSLDAIQPFLYNLFSDHDIIQIPKPIQKPVAFLISRLRAKKTKKYYEIMGGKSPQKEQTLQQAQKLQEKLEEDYKVVVAMRYWHPFTEEALNQLFQEKIKKIILLPLYPQYSRTTTGSSFNEFDRRVKRYINPGKFAVLSTLKGTKDPYYYFSNIPIAKINCYFDNPLYIKAMVENIKENLPEDYKDYYFLFTAHSLPEKIILDGDPYKKQTETTVKLIMEHFPNVKYSLAYQSKVGPVKWLEPFTDQEIERLIKEGYKKLIVIPVSFVSEHSETLYELDYLYGNIAKELGAESYIRIPTLKSHPMFIETLKELVIKNS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_AGRFC
Sequence: MSAKFDISFANSASLENALAIVLQASGEAQAVAGASEADPGGVIERASKISGFSAKSMATLDVIAPQGSSADRLLVIGLGKPSKLVAHDWLRAGGTAAAHFKKADKVVIYLDAPGVEVSAEAAADFALGLLLRAYSFDAYKTKKKSDDEKTPKKVDVTIVTAAHKDAEKASAVSEAIAGGVILARDLVNLPPNVLGPVEFAEKAEELRKLGVDVEILGEKELKKLGMNALLGVAQGSARPPRLAVMQWNGGSKKDEPIAFVGKGVVFDTGGISLKPGLGMEDMKGDMGGAAAVTGLMHVLAARKAKANVIGVIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADALWYTKDRFNPKFMINLATLTGAITVALGNLQAGLFSNDDELATRLAEAGEATAEKLWRMPLGKDYDKIIDSKFADMKNSSGRLAGSVTAAQFLKRFVGETPWAHLDIAGTAMGSPLTEINQSWGSGYGVRLLNELVRAHYED
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSA_PSYA2
Sequence: MTQKSFPITPEFLAAANVTAEQYVEQYQQSIASPEATDAFWAKQAELIDWIKKPTKISDVSYDLEDFRIKWFEDGELNISVNCLDRHVKNNPYKPAIIWEGDHPSLHKIISFKELHEAVCRLGNAMRKLGVKKGDRVTLYMPMIPEAVVAMLACTRIGAVHSVVFGGFSTQSLGNRIIDSQSKLVITADEGIRGNKRTPLKANVDRALDMDGTDSVSNVIVVHRTGNSVPMSGRRDIWYHSLVDGESQYCEPEVMNAEDPLFLLYTSGSTGKPKGVLHTTGGYITYALSTFRDVFDVKDDDVYWCTADVGWVTGHTYATYAPLANGTTTVMFEGVPEYPTWARIGHIIDKHQITVLYTAPTAIRAMMKEGDTFVRESDRSSLRLLGTVGEPINPEAWDWYYHIVGGGKCPVVDTWWQTETGGIMLAPIPGTVAMKPGAVMNPLYGIIPEVIDTDGVALEGAAEGNLVINGSWPGQMRTIYKDHARFLETYFTEYPGYYFTGDGVQRDEDGHYWITGRVDDVLNVSGHRLGTAEIESAIVAHPATAEAAVVGMPHDIRGIGICAFVILKSSETATESLKAELNRHVRTEIGPIANLDAIYMVNVLPKTRSGKIMRRILRSLAAGQYVGLGDLSTLADSSVINELVEVVKTERAK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL9_STAAW
Sequence: MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNLKQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEALKAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ATPB1_CERS1
Sequence: MATASQGKVTQVIGAVVDVQFDGGLPPILNALETENNGKRLVLEVAQHLGESTVRTIAMDATEGLVRGARVTDTGSPISVPVGDATLGRILNVIGEPIDEKGDLGEASTRAIHQPAPTFAEQSTTSEILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESGVIKIDNLSESKVALVYGQMNEPPGARARVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKAGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRAISELGIYPAVDPLDSTSRILDPQIVGEEHYNVARAVQGILQRYKSLQDIIAILGMDELSEEDKLSVARARKIQRFLSQPFDVAKVFTGSDGVQVPLEKTIASFKAVVNGEYDHLPEAAFYMVGDIEDVIAKAQRLAAQAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRAY_NITOC
Sequence: MLLYVTDYLARFDSGFHVFQYLTLRAILGVLTALVISFVVGPPMIRRLKFVGQPVRSNGPTTHLCKAGTPTMGGALILVAIAAATLLWADLSNRYIWVVLVVTLLFGGVGFVDDYKKLLAKDSRGLTSRYKYFWQSVIALGVALFLYFTASVAAETELIVPFFKDVAVNLGGYYVLLTYFVVVGSSNAVNLTDGLDGLAVLPTVLVGGALGIFAYAAGHSGFAQYLGIPYIPEAGELVVFCGALVGAGLGFLWFNAYPAQVFMGDIGALALGAALGILAVLVRQELVLFIMGGVFVVETVSVMLQVASYKLTGRRIFRMAPLHHHFEIKGWPEPRVIVRFWIITVILVLIGLATLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1014_CUPPJ
Sequence: MLIVLSPAKSLDYETPARTKTHTLPRFIERSAVLIDRLRKLAPQDVGALMDISDKLAVLNVTRYAEWSETFTAANSKQAVLAFNGDVYDGFDAKSLSADDLGFAQKHVRILSGLYGVLRPMDWMQPYRLEMGTRLDNAAGKDLYAFWGDDVTRLLNDDMAGLKHEGAPTLVNLASEEYFKVVRPKVLNARIITPVFEDWKGGRYKIISFHAKRARGTMARYAVTHRVTEPAALKRFAEDGYAFDAAASNDGRWVFRRRLED
What are the official names of this protein?
UPF0246 protein Reut_A1014.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CITG_STRS7
Sequence: MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFLTFVDSALALAPFFNTYLDIGFYHAKEDPGLIFERLRVSGIEAEQAMFSATKGVNTHKGVNFSLALLLGATGMYLASQPQLLAHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDLKKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYLMSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGGTADLLVLSLYFAFLENQL
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: YHHN_ECOL6
Sequence: MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQAPMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSFFWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALSAFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL
What are the official names of this protein?
Uncharacterized membrane protein YhhN.
What is the protein family that this protein belongs to?
Belongs to the TMEM86 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANN2_AREMA
Sequence: MTSTQSVAVYATLILAIFCFNDIHCDPIAEARAAAFGEREARSAGEWKQFDVNGEKVEVNEQENREIIRQAGGDGVEGSVMVIDHAKGLIIWSIPRAGECYLIGGVDKQLPDAQELLHYFRSAQGSADGEGVQSALDYVKAEDRPVTDLNLLAPEVREACQGKSVYWLEKSSGDNNEPEKRRWCVYAYVRIRGVLVRYRRCW
What is the function of this protein?
Has antimicrobial activity against the Gram-negative bacteria E. coli and P. mirabilis, the Gram-positive bacterium L. monocytogenes and the yeast C. albicans.
What are the official names of this protein?
Arenicin-2.
Protein: IRAP_SHIB3
Sequence: MKNLIAELLLKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIEQVDGALYEVKPDASIPDDDTELLRNYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGT1_CHICK
Sequence: MAALPVLVLVLLLACGGPRAAGQKRKEMVLSEKVSQLMEWTSKRSVIRMNGDKFRRLVKAPPRNYSVIVMFTALQPHRQCVVCKQADEEYQVLANSWRYSSAFTNKIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFAAEQLARWVADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRGSNLDFLYNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGQVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLHEAATSDMDVGKRKIMCIAGIGLVVFFFSWLLSVFRSKYHGYPYSFLMS
What is the function of this protein?
May be involved in Mg(2+) transport in epithelial cells.
What are the official names of this protein?
Magnesium transporter protein 1, MagT1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1, Oligosaccharyl transferase subunit MAGT1.
What is the protein family that this protein belongs to?
Belongs to the OST3/OST6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NADE_ALIFM
Sequence: MQQHIVEEMKVKVSIDPVEEIKKRVDFIKGKLLEAHCKSLILGISGGVDSTTCGRLAQLAVNELNLETQSSDYQFIAVRLPYGIQQDEDEAQLALQFIQPTHSISINIKDGVDGLHSANHIALQDTGLLPTDSAKIDFVKGNVKARARMIAQYEVAGYVGGLVLGTDHSAENITGFYTKFGDGACDLAPLFGLNKRQVREVAAQLGAPEQLVKKVPTADLEELAPQKADEDALSVSYDQIDDFLEGKKIDADAEARLIKIYQMSQHKRKPIPTIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: Y763_LEUMM
Sequence: MRKSDRSFYNWLMTNRNSMAANEVQQFANNAFLDSSFPKQSSDFDELSQYLEENTTYLMSMTTFDEAWSLYNAER
What are the official names of this protein?
UPF0346 protein LEUM_0763.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: CHX13_ARATH
Sequence: MELSMFGREDTNSSQWGEVHGPFMLEEIVCQAQNMLTSRGIFMKSNPLKYALPLLLLQMSVIIVTSRLIFRVLQPLKQGMISAQVLTGVVLGPSFLGHNVIYMNMFLPAGGKIIIQTLSNVGFVIHLFLLGLKIDGSIIRKAGSKAILIGTASYAFPFSLGNLTIMFISKTMGLPSDVISCTSSAISLSSMTSFPVTTTVLAELNILNSELGRLATHCSMVCEVCSWFVALAFNLYTRDRTMTSLYALSMIIGLLLVIYFVFRPIIVWLTQRKTKSMDKKDVVPFFPVLLLLSIASLSGEAMGVHAAFGAFWLGVSLPDGPPLGTELAAKLEMFASNLFLPCFIAISGLQTNFFEITESHEHHVVMIEIILLITYGCKFLGTAAASAYCQTQIGDALCLAFLMCCQGIIEVYTTIVWKDAQVVDTECFNLVIITILFVTGISRFLVVYLYDPSKRYKSKSKRTILNTRQHNLQLRLLLGLYNVENVPSMVNLLEATYPTRFNPISFFTLHLVELKGRAHALLTPHHQMNKLDPNTAQSTHIVNAFQRFEQKYQGALMAQHFTAAAPYSSINNDICTLALDKKATLIVIPFHKQYAIDGTVGQVNGPIRTINLNVLDAAPCSVAIFIDRGETEGRRSVLMTNTWQNVAMLFIGGKDDAEALALCMRMAEKPDLNVTMIHFRHKSALQDEDYSDMSEYNLISDFKSYAANKGKIHYVEEIVRDGVETTQVISSLGDAYDMVLVGRDHDLESSVLYGLTDWSECPELGVIGDMLTSPDFHFSVLVVHQQQGDDLLAMDDSYKLPNVEHQKIGDTGIQQRFSAEEGFTTIDLGKR
What is the function of this protein?
High-affinity potassium transporter that plays a role in K(+) acquisition.  May operate as a K(+)/H(+) symporter.
What are the official names of this protein?
Cation/H(+) symporter 13, Protein CATION/H+ EXCHANGER 13, AtCHX13.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROA_BACVZ
Sequence: MSEVLQKAALAKEAAAEMVMKTTAEKNEALQCIADGLRNERRLILTENQKDIEAGRNRGLTPDIIDRLTLDEKRLLDIADAVELLIGLEDPVGESLETIQKENGLSIEKIRVPLGVVGMIYEARPNVTVDAATLCLKTGNAVVLRGSSSAIHSNIALVSVMKRALGLSKLPIDAVQLIEDTSKETAKQLFTLNDGLDVLIPRGGKNLIDLVVRESTVPVLETGAGNCHVYIDESADPQMASEVVINAKTQRPSVCNAIESLLIHEKWAEEHGRKLLNQLTEKGVELRGDQVICRLEPQAKQAEEADWGAEYLAPILSVKTVQDVQEAVRHIQQYGTNHSEAILTENAEHAAYFQTAVDAAAVYHNASTRFTDGFEFGYGAEIGISTQKLHARGPMGLPALTSTKIIIKGNGQIRV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAA_YERPP
Sequence: MTNSIEQAWDLAKQRFAAVGVDVDAALTRLDTLPVSMHCWQGDDVTGFEDPDGVLTGGIQATGNYPGKARNATELRSDLELALALIPGPKRLNLHAIYLESDTPVARNKIEPRHFSHWVAWAKKHQLGLDFNPSCFSHPLSADGFTLSHADPEIRQFWIEHCQASRRVSAYFGEQLGTPSVMNIWIPDGMKDTPIDRLAPRQRLLSALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYAASRQTALCLDAGHFHPTEVISDKISSAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIIRHNLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTDRLRQLELRGDYTARLALLEEQKSLPWQAIWEGYCQRNDVPVDARWLDAVREYEQQILSQR
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2U_HUMAN
Sequence: MHGRAYLLLHRDFCDLKENNYKGITAKPVSEDMMEWEVEIEGLQNSVWQGLVFQLTIHFTSEYNYAPPVVKFITIPFHPNVDPHTGQPCIDFLDNPEKWNTNYTLSSILLALQVMLSNPVLENPVNLEAARILVKDESLYRTILRLFNRPLQMKDDSQELPKDPRKCIRPIKTTSFSDYYQTWSRIATSKATEYYRTPLLKVPNFIGQYYKWKKMDLQHQKEWNLKYSVIKCWLARKRMPHEVTHSMEEIKLCPTLIPTTDEIFLESPTAINSITDIYETEEEGWKSDTSLYENDTDEPREEEVEDLISWTNTLNTNTSED
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 U, E2 ubiquitin-conjugating enzyme U, Ubiquitin carrier protein U, Ubiquitin-protein ligase U.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: SPED_XANOM
Sequence: MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIEYIDEQYDADRLTQILTDVAEIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGRELISDAVVAHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIETLESDIVIMDYRVRGFTRDVKGKKHYIDHKINSIQHFLAKNVKSRYEMIDVNVYQENIFHTKMHLKDFDLDQYLFEERAKNLSFKERMKIETLLKREIEELFHGRNLSE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: CITE3_CHICK
Sequence: MAEHMMMSMSHGGTGLQSYRMGVSGLQGPPQHGQHVLRTLPAAGQMMPYGGAGMDGAMRPRPNLSGQMSHHQMQNAMMFNGPSQQQQQYMGPVGTQQLMASMHLQKLNTQYQGHPLGMSNGPMGAGAQQYRVGPSQHPGMQHMPSPALTLNVMDTDLIDEEVLTSLVLELGLDRIQELPELFLGQNEFDFISDFVSKQQPSAISC
What is the function of this protein?
Acts as transcriptional coactivator.  Enhances estrogen-dependent transactivation mediated by estrogen receptors.
What are the official names of this protein?
Cbp/p300-interacting transactivator 3, cCITED3.
What is the protein family that this protein belongs to?
Belongs to the CITED family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABZ_LEGPC
Sequence: MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQACGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKRDFWRMHGEAYIGDKLACSADLLSAAKEIKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y115_NPVOP
Sequence: MPTVWQLLFLLLVVAIVYVYALRFAQRFLQQDALARQHAAAAPLMHFAFQRARAVDCALNRLPCVTSQQCRDNCVIASAASDLTCDNGFCSATNILADAQAPGSAIECDPALGLLRVYAAGGDFVVSQTCVSTYRDLVDDTGAARPYLCDAGALRLELDTTPFSADACTCAAGYDKLMFRQTALARTVPVCIPTHAASLYRRVYG
What are the official names of this protein?
Uncharacterized 22.1 kDa protein.
Protein: NDVA_RHOP2
Sequence: MSLFRVYTRVLELLGKERRLGWTLAVANLLLATAQFAEPVLFGRIVDVMSGNLATGALAPEARSPWPLLAAWVGFGLFTIFCSAAVSLHADRLAHRQRQAVLTSYFEHILQLPTTFHTGTHSGRLIKVMLQGTDALWRVWLGFFREHFAALLSLLVLLPLSLYINWRLAMLLFALCGVFTVLTTLVVRKTYGLQSEVEAQYSDLSARASDALGNVALVQSYVRIDAEVQGLRFVADKLLAAQMPVLSWWALVTVITRASTTITVLAIFALGIVLNQQGLTSIGEIVMFVSFATLLIQRLEQVVSFVNSLMMEAPRLQEFIDVLDEVPAVRDRPNAIDPGRLSGLVEFQDVSFSYDGKRPAVEDLSFTALPGQTIALVGATGAGKSTAIALLHRAFDPQSGTVKIDGMDIRGLTLAGLRRNIGVVFQEALLFDRSIADNLRVGKPDATDAELRLAAERAQALDFIERSGLGFNTAAGERGRMLSGGERQRLSIARALLKDPPILILDEATSALDAVTEAKVNLALDEVMRGRTTFVIAHRLSTIRHATRILVFENGRVIESGTFDDLVAQRGHFAELARAQFMVQEDARASVAAAADHASVRP
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUCD_STAAR
Sequence: MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYELLLTVNK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.