PharMolix/UniProtQA huggingface dataset:
Protein: RAPA_KLEP3
Sequence: MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQQNYRPVADAVALLLAGNTLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESTDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRLLLDKNGNNLAGQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAALGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESNRQQVMDALAQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: MATK_TRIMC
Sequence: MEELQGYLEKDGSRQQNFLYPLIFQEYIYTLAHDHGLNSSIFYEPMEIVGLGYDNKSSSVLVKRLITRMYQQNSLIYSMNDFNQNRFVGHNNSFYSNLDSQMVSEGFAVIVEIPFSLRLVPSSEEIPKSQNLRSIHSIFPFLEDKLSHLNYVLDILIPYPIHLEILVQILQCWIQDVPSLHFLRLFLHEFHNWNNLITPTKSISVFSKENKRLFRILYNSYVSEYEFVFVFLRKQSYYLRSTSSRAFLERTHFYVKIEHLIDIDVCHNHFQKILWFFKDSFMHYVRYKGKAILASRGTYLLIKKWKCYLVNFWQYNFHFWSKPYRIHINPFSNYSFYFLGYISSVLINPSAVKNQMLENFYLVDTLTQKFDTIVPVIPLIGSLSKAKFCTILGHPISKPIWAELSDSDIIDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRNLLQRLGSGLLEEFFTEEEQVISPIFPKTTLFPLHGSHKERIWYLDIIRINDLANYLDWS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS4_ENTFA
Sequence: MSRYTGPSWKVSRRLGISLSGTGKELARRPYKPGQHGPNSRGKVSEYGMQLTEKQKLRHMYGMNERQFRTLFIKASKIKEGKHGVNFMVLLEQRLDNVVYRLGLATTRRQARQLVNHGHITVDGKRVDIPSYHVEVGQVIGVREKSQNISTIKEAVEATVGRPAFVSFDTEKLEGSFTRLPERDELYPEIDEALVVEYYNQKL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MATRX_NDVB1
Sequence: MDSSRTIGLYFDSAHSSSNLLAFPIVLQDTGDGKKQIAPQYRIQRLDLWTDSKEDSVFITTYGFIFQVGNEEATVGIIDDKPKRELLSAAMLCLGSVPNTGDLIELARACLTMMVTCKKSATNTERMVFSVVQAPQVLQSCRVVANKYSSVNAVKHVKAPEKIPGSGTLEYKVNFVSLTVVPKKDVYKIPAAVLKISGSSLYNLALNVTINVEVDPRSPLVKSLSKSDSGYYANLFLHIGLMTTVDRKGKKVTFDKLEKKIRSLDLSVGLSDVLGPSVLVKARGARTKLLAPFFSSSGTACYPIANASPQVAKILWSQTACLRSVKIIIQAGTQRAVAVTADHEVTSTKLEKGHTLAKYNPFKK
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: SLX1_TALMQ
Sequence: MISTAPADLPSPKPIPAFYCCYLLRSVKKPSSLYIGSTPDPARRLEQHNGFTKGGAKRTERDTLRPWEMITIIEGFTSRTGALQFEWSWQHVHTTRHIGAVETDQLNRRRKDPPVDQGSGIWTSTPKVLGNLHQLLRSTYFGTWPLTVRFLSTEAHSHWQRWTERADGLLPDTIHVELDFHAEGASVLDSNLPANDMTHINATYSGIQDHLEKSASLLNDSAKTLACEVCKKLLSPHGDVIVVCSQPHCHAVSHVKCLSQLFLRDEGSSGLVPTLGDCPACKREVTWVALMKELSMRLHGAKIATKLLKKERKSKAISDSRKSSKSGKKTANTYADILGNDYDDLDEDWMNSVNVDSGSEPLDHKFTNANNSTGRVEIVIEDSEEETFD
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDF1_MOUSE
Sequence: MDAKVVAVLALVLAALCISDGKPVSLSYRCPCRFFESHIARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRLKM
What is the function of this protein?
Chemoattractant active on T-lymphocytes and monocytes but not neutrophils.  Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis.  Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1.  Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner (By similarity).  Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase.  Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins.  SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase.  Plays a protective role after myocardial infarction.  Induces down-regulation and internalization of ACKR3 expressed in various cells (By similarity).  Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation.  Stimulates the proliferation of bone marrow-derived B-cell progenitors in the presence of IL7 as well as growth of stromal cell-dependent pre-B-cells (PubMed:8134392).
What are the official names of this protein?
Stromal cell-derived factor 1, SDF-1, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, TPAR1, C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor, PBSF, Thymic lymphoma cell-stimulating factor, TLSF.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPB_SYNFM
Sequence: MLRKAFLLNLGMLDYNRSRDLQKRLHARRVIDVVPDTVLLVEHPHTITLGRRGNRLCLKASPEDLERMGIPVVQVERGGDVTYHGPGQAVVYPILHLRESGLSLADYVSALESLVIGVLGDFGIKGRRNGKNRGVWVGGDKIASVGIAVSRWVSYHGIALNCTTNLEYFGLIDACGLKGVEMTSISRLLGKDVSGSEVHRSIAFHLRRLFERDWQERTLPEIEALLND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_HELPJ
Sequence: MAYFLEQTDSEIFEFIVEEFKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQFANVQAHSGSQANNAVYHALLKLYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVGLDGYIDYEEALKIAQSVKPQIIVCGFSAYPREIDFKKFREIADAVGALLLGDIAHVAGLVVANEHAHPFPHCHVVSSTTHKTLRGPRGGLILTNDEEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFKAYAKLVKSNMQVLAKTLKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRNPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLHVKEELKTMANQFPVYHQPIF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTJA_ECO57
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IOVO_AIXSP
Sequence: VATVDCSGYPKPACTMEYMPLCGSDNKTYGNKCNFCNAVVDSNGTLTLSHFGEC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_BURVG
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFTDAQKYVRQLAANRGTILFVGTKRQSRDTIAQEAQRAGMPYVNARWLGGMMTNFKTLKVSIKRLKDMEAAVEAGETEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVIDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAQGVADAILEGRANAVNEVVQAVRGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS14Z_THEMA
Sequence: MAKKAMIERWKKPKKYKVREYTRCHICGRPRAVYREFGLCRICFRKLALEGKLPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: BCSC2_KOMSB
Sequence: MNRRYALSLSGALLASSCMTVLVAVPVARAQQASTAVTSTAASPAAAPRQILLQQARFWLQQQQYDNARQALQNAQRIAPDAPDVLEVEGEYQAAVGNREAAADTLRHLQQVAPASTAVSNLSDLLSERAISQSDLSQIRSLAGSGQNAQAVAGYQKLFHGGKPPRSLAVEYYQTMAGVPTQWDQARAGLAGIVASNPQNYRAQLAFAQALTYNTSTRMEGLTRLKDLQSFQSQAPVEAAAATQSYRQTLSWLPVNPDTQPLMEQWLSAHPNDAALREHMLHPPGGPPDKAGLARQAGYQQLNAGRLSAAEQSFQSALQINSHDADSLGGMGLVSMRQGDTAEAHRYFEEAMAADPKTADRWRPALAGMAVSGDYAAVRQLIAAHQYTEAKQKLATLARQPGQYTGATLMLADLQRSTGQVAAAEQEYRGILSREPNNQLALMGLARVDMAQGNTAEARQLLSRVSPQYASQVGEIEVSGLMAAASQTSDSARKVSILREAMAQAPRDPWVRINLANALQQQGDVAEAGRVMQPILANPVTAQDRQAGILYTYGSGNDAMTRQLLAGLSPADYSPAIRSIAEEMEIKQDLASRLSMVSNPVPLIREALSQPDPTGARGVAVADLFRQRGDMVHARMALRIASTRTIDLSPDQRLSYATEYMKISNPVAAARLLAPLGDGTGSGAGNALLPEQMQTLQQLRMGISVAQSDLLNQRGDQAQAYDHLAPALQADPEATSPKLALARLYNGHGKPGKALEIDLAVLRHNPQDLDARQAAVQAAVNSNHNSLATRLAMDGVQESPMDARAWLAMAVADQADGHGQRTIEDLRRAYDLRLQQVEGTRAASGPVGAHEEALAPPSTNPFQSRGYGHQVELGAPVTGGSYSAEAASPDTSDQMLSSIAGQIHTLRENLAPSIDGGLGFRSRSGEHGMGRLTEANIPIVGRLPLQAGASALTFSITPTMIWSGQLNTGSVYDVPRYGTFMATQAANQCAGHSSCGGLDFLSANHTQRIAAGAGEAGFAPDVQFGNSWVRADVCASPIGFPITNVLGGVEFSPRVGPVTFRVSAERRSITNSVLSYGGLRDPNYNSEVGRYARQVYGHDLTKQWGSEWGGVVTNHFHGQVEATLGNTILYGGGGYAIQTGKNVQRNSEREAGIGANTLVWHNANMLVRIGVSLTYFGYAHNEDFYTYGQGGYFSPQSYYAATVPVRYAGQHKRLDWDVTGSVGYQVFHEHAAPFFPTSSLLQSGANYVASNFVQNALPTDYLSQETVNSAYYPGDSIAGLTGGFNARVGYRFTRNVRLDLSGRYQKAGNWTESGAMISAHYLIMDQ
What is the function of this protein?
Required for maximal bacterial cellulose synthesis.  It may be involved in the formation of a membrane complex for extrusion of the cellulose product (By similarity).
What are the official names of this protein?
Cellulose synthase operon protein C.
What is the protein family that this protein belongs to?
Belongs to the AcsC/BcsC family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: TCR_BACIU
Sequence: MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_ECOK1
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: KTU_XENLA
Sequence: MAEKLQNLELSSEELDRFTKAFQDPKFREMFVQYAEEIRDPENRRKYEQEISQMESERGMDIKFIHPKPGYVLLTSVNGVQKCYLNICSNDLLQKPECKPGKDGEGKAGLHWSLPYSLSAGREDLGKDGSKHVIYDVVFHPDTLHIASKNEKFKMIVDSTSLEAVASQFDVKLDKANVRTLSMKYKGVPNPSVLRKPLLGTTPKHGDPEDPLSFPYPYDVPTAVGKEKKDQKRVIKEEHKQHVTTSEQDPDIQIATTPNYTVRHRSYVDLQDFRDSRDSTPSPVPKELVITVDLPLLNSAESVNLHIAGKNLSLESEKPAYKLNVKLPYVVEDNQGKAQFNKARRQLIITVPVIQHNILTLMQDHFEEARGEKDLRGAESSVLHEEYTDNGSRTSACGTENKLEPLISCLNEEENNSEGLTSESNLDTGAPYLPEISPNQNTLDREEVVYGLTEDVPSMPSDTLVCPTFSCSQDPTSLTLIAHVRDIDENSISTDVGSNHYHIRCSVKQSTSSYDLLVTFLPHDIINPNEVYVNISENNALIGLTKSPESVGFWKMLYFGVSGQPLQERRFVSEDNINEVLACSIPLSQVSPSTQEHQPLIEVLEMTDERTHIRINKPKTECVVSAEHKEHCTDHSEHERDVGVERSNIAVGDTTEHYSNQVSPCRENTELDRDHTSERYEEPESTSCTGESTSDQQQKDSNLVFPGDSSAENKMACLKSSEQTTQESDLAEDDMPDRSDHTQNFDSRPASSSVLKEIGKKDGSVQVISDHTTQCPFQFQNSLLFDLD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia.
Protein: LEPA_MESHJ
Sequence: MDNKKIRNFAIIAHIDHGKSTLADRILEFTNTVSKRDLKEQHLDSMDLEKERGITIKLNAVQIRYNSYIFHLIDTPGHVDFTYEVSRSLAATEGALLLVDASQGIQAQTLANVYLALENNLEIIPIINKIDLPSANVDKVKAEIENTIGISAENAILISAKNGIGIEKVLEAIVNLIPPPQASDEKDPLKALVFDSYFDIYRGVIIFIRVVTGKISVGDTFKFMANNLKFSVIELGISSPNQVKKEALFAGEVGWVAASIRNAKDVEVGDTITLVENPAKSPLPGYKKLVPVMYTGFYPVDSQQYNLLKDSLEKISLSDSSIIYEPESSKALGFGFRIGFLGLLHMEILQERLEREFNLSIIATAPSVEFQITRTNGQVQIISNPSLFPEPNFISEIREPYILAKIFLPEEFLGQIMGLCQDKRGIYVDLEYIDDFRRRLIYKLPLVEVIFDFFDRLKSLSKGYASFEYEVIDYQVSKLQKLDILLNGQKIDALSMIVHKDFAYPKARDLTQKLKEIIPRHSFEVPVQAVIGSKVIARETIKAYRKDVTAKLYGGDVTRRKKLLEKQKAGKKRMKSFGVVDVPQEAFLAILKTNVSEK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LIS1_XENLA
Sequence: MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDMNEELDIKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPIGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVTASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECLRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSTISDATGSETKRSGKPGPFLLSGSRDKTIKMWDISIGMCLMTLVGHDNWVRGVQFHPGGKFILSCADDKTIRIWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
What is the function of this protein?
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in PAF inactivation.  Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner (By similarity).  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome.  May be required for proliferation of neuronal precursors and neuronal migration.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: ANTDC_ACIAD
Sequence: MNHSVALNFADGKTFFIAVQEDELLLDAAVRQGINLPLDCREGVCGTCQGTCETGIYEQEYVDEDALSERDLAKRKMLACQTRVKSNAAFYFDHHSSICNAGETLKIATVVTGVELVSETTAILHLDASQHVKQLDFLPGQYARLQIPDTDDWRSYSFANRPNASNQLQFLIRLLPNGVMSNYLRERCQVGQTLIMEAPLGSFYLREVERPLVFIAGGTGLSAFLGMLDNIAEQPNQPSVHLYYGVNTEADLCEQKRLTTYAERIKNFSYHPIISKASEQWQGKSGFIHEHLDKNQLSEQSFDMYLCGPPPMIEAVKTWLDEQAIADCHIYSEKFLQSNTAKT
What is the function of this protein?
Electron transfer component of anthranilate 1,2-dioxygenase system.
What are the official names of this protein?
Anthranilate 1,2-dioxygenase electron transfer component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: MVP_CMVY
Sequence: MAFQGTSRTLTQQSSAATSDDLQKILFSPEAIKKMATECDLGRHHWMRADNAISVRPLVPEVTHGRIASFFKSGYDVGELCSKGYMSVPQVLCAVTRTVSTDAEGSLRIYLADLGDKELSPIDGQCVSLHNHDLPALVSFQPTYDCPMETVGNRKRCFAVVIERHGYIGYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNIESSQYLLTNAKINQNARSESEELNVESPPAAIGSSSASRSEAFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: FER_CANLF
Sequence: MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQMNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSFIGVHQQIEAEMIKVTKTELEKLKSSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHVLHNQYVLALKGAQLHQNQYYDTTLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNLTAESLQVMLKTLAEELIQTQQMLVNKEEAVLELEKRIEESSKTCEKKSDIVLLLSQKQTLEELKQSVQQLRCTEAKFTAQKELLEQKVQENEGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIAGIIRSPKSALGSSTFSDTIPISEKPLAEQDWYHGAIPRIEAQDLLKQQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQFVDNLYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILKDKTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIYIIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQATEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENRPKFSELQKELTVIKKKVTQ
What is the function of this protein?
Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell attachment and cell migration.  Acts downstream of EGFR, PDGFRA and PDGFRB.  Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation.  Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.  Plays a role in the regulation of mast cell degranulation.  Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11 (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Fer, Proto-oncogene c-Fer, p94-Fer.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell junction. Membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cytoplasm, cell cortex. Note=Associated with the chromatin. Detected on microtubules in polarized and motile vascular endothelial cells. Colocalizes with F-actin at the cell cortex. Colocalizes with PECAM1 and CTNND1 at nascent cell-cell contacts (By similarity).
Protein: RS16_BRUME
Sequence: MALKIRLARAGSKKRPYYHVVVADVRAPRDGRFIETVGSWNPVLPKDAERVKLDAERIQHWIAQGAQPTDRVLRFLDQAGIAKRPSRNNPTKGEPGKKAQERLALAKQAEEEAAAKAAEAAAAAAAPAEEAASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RPB4_DICDI
Sequence: MTDPLIKRSGIQEEEDLTTLKFPRDLKDAKFLLNSEVAILLEHRKGISESEGTEFPQNTLLIHLYYNSINDIIRTFHKTLAYAEKFSRYKNKTSIKQVRTALSKQNLEEFEIASLANLCPEISDEAKSLIPSLKKMEDDELQAILDELSNLRKFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element.  The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft.  The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit rpb4, RNA polymerase II subunit B4, DNA-directed RNA polymerase II subunit D.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.