PharMolix/UniProtQA huggingface dataset:
Protein: GSA_CHLCV
Sequence: MPVIDETPMTYTEACRYFPGGVNSPIRACIPVGIVPPIVSSASRDVFIDSFGKNFIDFCGSWGSLIHGHSHPKILDALCSAASQGTSYGLTSENEISLATTLFSCLGLQDHKLRFVSSGTEAAMTSVRLACGVTQRSVMIKFLGCYHGHADVLLKGMTIDENNLMEVPHLVDRYFSSDPCLPLTLILPYNDLKTFEEVMEKIGERVACVIFEPIAINMGVVLPEAGWIESIITTCRRYGALSIMDEVVTGFRMGSRGMRSILDVTPDITVYGKILGGGMPVAAVLAHQSIMEHLMPVGTVFQAGTLSGNPIAMAAGQASIELCQERDFYPKLENLTEGFLSPIEDFIRCKGFPIALVRAGSMFSFFFRETPPRNLRDVQECDQKTFGIFYRHAFSRGVYLSPASMEASFISSVHSRENLAYTQNVLIDSLVKTFEGI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_BACTN
Sequence: MAERKVRVRFAPSPTGALHIGGVRTALYNYLFARQHGGDLIFRIEDTDSNRFVPGAEEYILESFKWLGIHFDEGVSFGGEHGPYRQSERREIYKKYVQILLDNDKAYIAFDTPEELDAKRAEIANFQYDASTRGMMRNSLTMSKEEVDALIAEGKQYVVRFKIEPNEDVHVNDLIRGEVVINSSILDDKVLYKSADELPTYHLANIVDDHLMEVSHVIRGEEWLPSAPLHVLLYRAFGWEDTMPEFAHLPLLLKPEGNGKLSKRDGDRLGFPVFPLEWRPESGEVSSGYRESGYLPEAVINFLALLGWNPGNDQEVMSMDEMIKLFDIHRCSKSGAKFDYKKGIWFNHQYIQLKPNEEIAELFLPVLKEHGVEAPFEKVVTVVGMMKDRVSFIKELWDVCSFFFVAPAEYDEKTVKKRWKEDSAKCMTELAEVIAGIEDFSIEGQEKVVMDWIAEKGYHTGNIMNAFRLTLVGEGKGPHMFDISWVLGKEETLARMKRAVEVLK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_RABIT
Sequence: MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAVGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKDERADLIAYLKKATNE
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: S12A9_XENLA
Sequence: MTSESSPLLHYRLFSVSDGGLGPPDSSPIMTDAVTVGTGPTQRKLSTFFGVVVPTVLSMFSIVVFMRIGFVVGHAGLLQSLLMLFVAYVIIWLTVLSVCAISTNGAVQGGGAYFMISRTLGPEFGGSIGLMFYLANVFACGVYVLGLVEAVLDVFGRDPSDVTDSLRSLPQGYGYSFLYASIILLLCMAICLVGASIYSQASFFIFLLVFVVLLTILISFLAVRPLTVSIRHGGNVTMTGVYTGINSSTLHNNLQADYSLDYTTGNLMNFATVFAVMFNGCTGIMAGCNLSGELKQPSRSIPMGTIIAVIITFFVYLILFIFTAFTCDRTLLREDYGFFRSINIWPPFVLIGVYATSLSASMSTLIGASRILHALAKDDLFGVLLAPAKLVSKGGNPWGAVVYTWALVQLVLLAGKLNTIAGIVTVFYLIAYAAIDLACLALEWASAPNFRPTFRFFSWHTCLLGILSSLVMMFLINPAYASGSIVLLLLLLGSIHFRSSSSSWGYISQALIFHQVRKYLLLLDVRKDHVKFWRPQILLMVSNPRTSSQLIRFVNDLKKGGLYILGHVETGDLDTLPSDPVQTHYSFWLSLVDKLNVKAFVDLTLCPSVRQGTQHLLRITGLGGMKPNTVVLGFYDDACPDDYFLQDSLFTPGLSPKDDAFGVDATSLQAHFPPARDPETPRLLSAKDYVSMICDALKMHKNIVLARNFPLLVRPEASSSSPATYIDVWPLDLLRPQASAYVDVCSLFLLQMACILNMAASWRRYQLRVFLCVESRGGSDGASGWLAAEAKFRELLSKLRIRALIRVVAWDRVAAFRVQNMGGQVLNREPISSEYLNAAKSAVTDEGGTETAVRFLYLPRPPADSSLHERYLEELDTLTSGLGPTLLIHGLTPVTCTEL
What is the function of this protein?
Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function.
What are the official names of this protein?
Solute carrier family 12 member 9, Cation-chloride cotransporter-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNAPN_RAT
Sequence: MAAAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDSGVYPPGSPSK
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.  May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25.  Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis.  May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:10195194, PubMed:11283605).  As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (By similarity).
What are the official names of this protein?
SNARE-associated protein Snapin, Biogenesis of lysosome-related organelles complex 1 subunit 7, BLOC-1 subunit 7, Synaptosomal-associated protein 25-binding protein, SNAP-associated protein.
What is the protein family that this protein belongs to?
Belongs to the SNAPIN family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Golgi apparatus membrane. Lysosome membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Note=Colocalizes with NANOS1 and PUM2 in the perinuclear region of germ cells.
Protein: RNPA_PARMW
Sequence: MALPASMRLRGHRCFNRLHRIGRRHHGDWMVLRVMPEEPRLLRPELRRHPTRCCRCALVISSKVSKRAVRRNRLRRLLHQHLRQQLEHRGDLAGRWVLISLRPEASEAEPSQLLEECDSLLSSAGLGQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GP135_RAT
Sequence: MEEQARPPSRPAASATLPGSAHPGGAASTATAAALSFSSVATVTLGNQSDAGRPEAAGSRGPAPLLWHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFAPPGDSGPWRSFCAASRFFSSCFGIVSTFSVALISLDRYCAIVRPPRDKLGRRRALQLLAGAWLAALGFSLPWELLRAPREPPTPQSFHRCLYRTSPDPAQLGAAYSVGLVVACYLLPFLLMCFCRYHICKTVRLSDVRVRPMTTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAATRQGQTTQAPSLLNVAAVWLTWANGAINPVIYAIRNPNISMFLGRNREEGYRTRNMDVFLPSQGLGFQARSRNRLRNGCANRLGACSRMPSSNPASGSGGEVVMWARKNPVVLFFREDPPDPVMAVYKQHKSETRDSSI
What is the function of this protein?
Orphan receptor.  Has spontaneous activity for beta-arrestin recruitment.  Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity).
What are the official names of this protein?
G-protein coupled receptor 135.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome.
Protein: TM127_MOUSE
Sequence: MYAPGGAGLPGGRRRRSPGSSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVNPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENDPYPAEYEVINQFQPPPAYTP
What is the function of this protein?
Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1.  May act as a tumor suppressor.
What are the official names of this protein?
Transmembrane protein 127.
What is the protein family that this protein belongs to?
Belongs to the TMEM127 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Association of TMEM127 with the cell membrane is enhanced by inhibition of endocytosis. In the cytoplasm, it colocalizes with markers of early endosomal structures, Golgi apparatus and lysosomes.
Protein: GCST_CUPNH
Sequence: MTLQATPLNAIHRALGARMVDFGGWDMPVNYGSQIEEHNAVRTDAGMFDVSHMCVVDLAGANTRSFLRGLLANNVDKLQTPGKALYSCMLDEKGGVIDDLIVYFFAEDRFRLVVNASTALGDIEWIRARNAATGSDVTITPRREDVAPAGVQPLAIVAVQGPNARTKVWSTFPSTQPSDTLKPFNAAVVQDPALGEIMVARTGYTGEDGFELVVPAENVAAIWEKLNAAGVRPAGLGARDTLRLEAGMNLYGQDMDINTSPLDAGLAWTVDLQSERDFTGKAALAAAGSRQQFLGLILRDKGGVLRAHQKVITPAGDGEITSGTFSPSLSQSIAFARLPKDVAVGDTVQVEIRDRKLNATVVKLPFVRNGKALVS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: CP2CU_RABIT
Sequence: MDLFIVLVICLSCLLLVSLLKQSYARRKLPPGPTAFPLVGNVLQLDRKNISKSISMLAKEYGPVFTVYFGTKPSVVLHGYEAVKEALVDHGEEFSGRVTVPVFDRYAQGAGLFASQGELWKETRRFTLTVLRNMGMGKKTIEDRIQEEASCLVKALKETNASPCDPSSLLFCVPCNVICSIIFQNRFEYNDQTFQTLVKHFLDSIRLFNTPWMQLYNTFPILHYLPGSHHELFKVFNDQMKFFSEKIREHQESLDHNNPRDFIDYLLIKMEKEKHNKQSQFTMHHLLVTIWDVFDAGSQTTSSTMQFGLLLLMKHPEIAAKVQEEIERVIGRDRSPCMQDRSCMPYTDAVIHEIQRYIDMVPNNVPHAVTQDIQFRGYLIPKGTHILPSLTSVLYDEKEFPNPEKFDPGHFLDASGNFKKSDYFLPFSIGKRACAGEGLARMELFLVLTTILQHFTLKPLVDPKDIDPTPVDNGFLSVPPSYELCFVPV
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2C30, CYPIIC30.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: FTSK_CLOPE
Sequence: MAGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLIGLFGIGAFFIPIYIIYLCTKLFLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQGSIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFVIFVTLYLISSMLIFDYNLVSIRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDFMKNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEESIDKEISNNIASKGSSVGASYVAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFGVEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALGLAAKGVRIEAPIPGKSAIGIEVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSGKSVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWAVNEMTRRYKLFADNGVRNIESYNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYICRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDSAGAEKLLGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIASEGNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGSKPRQVLLSKDELENMK
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: MNTH_STAA8
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNTFR_HUMAN
Sequence: MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLALAAAAATASSLLI
What is the function of this protein?
Binds to CNTF.  The alpha subunit provides the receptor specificity.  Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1 (PubMed:26858303).  Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1 (PubMed:19386761).
What are the official names of this protein?
Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: OR5P3_HUMAN
Sequence: MGTGNDTTVVEFTLLGLSEDTTVCAILFLVFLGIYVVTLMGNISIIVLIRRSHHLHTPMYIFLCHLAFVDIGYSSSVTPVMLMSFLRKETSLPVAGCVAQLCSVVTFGTAECFLLAAMAYDRYVAICSPLLYSTCMSPGVCIILVGMSYLGGCVNAWTFIGCLLRLSFCGPNKVNHFFCDYSPLLKLACSHDFTFEIIPAISSGSIIVATVCVIAISYIYILITILKMHSTKGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYTVVIPMLNPLIYSLRNKEIKGALKRELRIKIFS
What is the function of this protein?
Odorant receptor (Potential).  May be involved in taste perception.
What are the official names of this protein?
Olfactory receptor 5P3, Olfactory receptor OR11-94, Olfactory receptor-like protein JCG1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEPT_VIBA3
Sequence: MEKLVERFLNYVTFDTKSDPSNQQCPSSPGQITFAEALKLELVALDLVDVSLDDNGYLMAKLPSNVDYPVPAIGFVAHMDTAPDASGANVKPQVIKDYRGGTIELGESGESLSPSQYPDLDSLHGHDLITTDGTTLLGADNKAGIAEIISAIAYLKANPDIKHGDICIGFTPDEEIGRGANLFDVEKFGAEWAYTIDGGPVGELEFENFNATSADVICHGVNVHPGTAKGKMVNSMNIAAQFQLMMPAQETPECTEGYEGFYHLKSAEMGVARSELGYIIRDFEREGVEARKAVMQQKVDELNERLEKGRVELVLTDSYFNMKEMVEPHQHIIELAKQAMIECDVEPMIKPIRGGTDGARLSFMGLPCPNIFTGGYNFHGIHEFITIQGMEQAVKVIVELSQRTATHYQK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLF3_MOUSE
Sequence: MLMFDPVPVKQEAMDPVSVSFPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLTHGIQVEPVDLTVNKRGSPPAAGGSPSSLKFPSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPLLQKKIKIEPGIEPQRTDYYPEEMSPPLMNPVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
What is the function of this protein?
Binds to the CACCC box of erythroid cell-expressed genes.  May play a role in hematopoiesis.
What are the official names of this protein?
Krueppel-like factor 3, Basic krueppel-like factor, CACCC-box-binding protein BKLF, TEF-2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DXS_BACMK
Sequence: MDLTQIQNPSFLKDMSISELEGLSEDIRKFLIEELSQTGGHIAPNLGVVELTIALHKLFDSPKDKFLWDVGHQSYVHKILTGRAKEFGTLRQYQGLCGFPKRCESEHDVWETGHSSTSLSAAMGMALARDLKKTEEYVIPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNVLGRLRTAGKYHWVKDELEYILKKIPAVGGKVAATAEKIKDSLKYLLVSGVFFEELGFTYLGPVDGHDYEKLFETLQYAKKTKGPVLVHVITKKGKGYKPAESDVIGTWHGTGSYKIESGDFVKPKEVAPAWSAVVSETVLKLARTDERIVAITPAMPVGSKLEKFQKEFPDRMIDVGIAEQHATTMAAGMATQGMKPFLAIYSTFLQRAYDQVVHDICRQNLNVFIGIDRSGLVGADGETHQGVFDIAFLRHLPNMVLMMPKDENEGQHLVYTAMQYEDGPIALRYARGNGLGVQMDEELKAIPIGTWETLKEGTQAAILTFGTTIPMAMEAAERLEQAGVSVKVVNARFIKPMDEAYLHELLGKNIPILTIEEACLIGGFGTGVVEFASENGYHSALIERMGIPDRFIEHGSVTKLLEEIGLTTDAVVDRIHTMIPSKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RBL2A_MOUSE
Sequence: MAGDRNRHCELEQEKYDTHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQDFMDEVLQELENFKLEQKEEDTSGQEQSDTTKSPSPS
What is the function of this protein?
Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.  Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail.
What are the official names of this protein?
Rab-like protein 2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: MTNC_SYNSC
Sequence: MNQQHLLLDIEGTTCPVRFVSDTLFPFAKKELSRYITQNWDKRPHSKSIRAAWKEWMDDQSAESMIIKQQVTQCEIEEVEGLIQYLKHLISIDRKSTALKDLQGKIWEYGYGNGELKSQLFPETAVCLRQWHEQGLTLSVYSSGSIQAQKLLYRHSLNGNLEDLFSHWFDTHTGPKKSAESYTTIAKQLQSSPNKIWFVSDNGDECNSARLAGMHTLFSLREGNPDRDPRDHKVVHSLREVSALLIAEQ
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RLME_FRAT1
Sequence: MSKGSSTKKWLHEHTSDYYVIQANKLGYRSRASFKILEIQDKYQLFKPNMFVVDLGAAPGGWSEQVIKYIGKNGKLIALDLLEMAPIAGVEFIQGDFSSDETYQKLNTLVNNQKIDCVISDMAPNLSGNKTSDQAKSIYLLELALDFANTNLNKNGSFVAKVFQGQGSDEYLKLVRESFNKVIQFKPKSSRAKSREFYVIATEFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_CORA7
Sequence: MTIKVGVLGAKGRVGQAIVEGVNAAEDLELVASIDRGTPLEKLVESGAEVAVDFTQPASVMDNLEFCIAHGIHAVVGTTGFDSERLAKVEGWTQKEDAGNVLIAPNFAISAVLTMVFAAQAAKFFDSAEVVEYHHPNKLDAPSGTAVHTAQGIANARQEAGLDAMPDKTEQSLDGARGADVDGVHVHAVRMQGMVAHEEVIFGTQGQSLTIRQDSYDRSSFTPGVLLGVREIASHPGLTVGLEKYLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_SYNSC
Sequence: MRFSTLIKVLQTGDAGLRWSQAGLDPWLEGAASLDQASAAQLSFLEKGNALTAALGASGVGALLLPDQQDLIDLASQRGIAFAVFADPRLAFAEALDQLYPRRRPLAEIHPSAVIDERAVVGPGTAVGPRVCIGEGSRLGADCIVHPGVVIYDDVVVGDGCELHANAVLHPGSRLGRGCVVNSNAVVGSEGFGFVPTAKGWRKMPQTGQVVLEDGVEVGCGTTIDRPSVGETRIGAGTKIDNLVQIGHGVTTGRGCAFASQVGIAGGARIGHGVILAGQVGVANRAVVGDRAIASSKSGIHGDVAPGEVVSGFPAIPNRLWLRCANTFSKLPEMAKTLRELKRDTPQ
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYK_CHLTE
Sequence: MSNAPEQKNPQNDPSPAVSLNDQMKRRFEERTHLAEAGINPYPYKFDVTTTSKAIIDSFSDENPADVSVAGRIMAIRRMGKASFLHIQDSEGRIQIYLKKDDVGEASYNTFKLLDIGDIVGVSGFTFKTKTGEISVHARQFELLAKSLRPIPIAKEKEVDGQKVIYDAFSDRELRYRQRYVDLIVNPEVRGTFIKRTKIVALMRNYFASNGWLEVETPILQPIYGGAAARPFTTHHNALDMQLYLRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYIWMMELVEDLLHKACVEVNGKDSTMFLGNEINLKPPFRRLTIADSIREYTGMEIRGKSEAQLRDIAKDLGLELDPKISSGKIIDEIFGEFVEPKLIQPTFITDYPEEMSPLAKKHRSEPGLVERFELIVGGKEVCNSFSELNDPVIQRERLEEQARLRQRGDDEAMIVDEDFLRALEYGMPPCAGLGIGIDRMVMLLTGQDSIRDVIFFPHMKPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNMP2_OSTFU
Sequence: MLGKHTKLFFGVSLVALIVSVILAAWGFPKIVSKQIQKNIQIDNSSVMFEKWRKIPMPLTFNVYVFNVTNVEDVNNGAKPRLQQIGPYAYKEYRERTVLGYGDNDTVSYTLKKTFIFDQEASGLLSEDDEVTVIHFSYMAAILTVNDMMPSITGVVNGALEQFFTNLTDPFLRVKVKDLFFDGVYVNCAGNHSALGLVCGKLKADAPQTMRPAGDGNGFYFSMFSHMNRTESGPYEMIRGRENIKELGHIISYKGKSFMKNWGNDMYCGQLNGSDASIFPPIDENNVPEKLYTFEPEVCRSLYASLVGKSSIFNMSAYYYEISSDALASKSANPGNKCYCKKNWSANHDGCLIMGILNLMPCQDAPAIASLPHFYLASEELLEYFDGGISPDKEKHNTYIYLEPVTGVVLKGLRRLQFNIELRNIPMVPQLAKVPTGLFPLLWIEEGAELPDSIIQELRQSHTLLGYVEAVRWALLAIAIVATAISAIAVARSGLIPVWPRNANSVSFILSPHPNSDVNKVH
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.