PharMolix/UniProtQA huggingface dataset:
Protein: YQGF_SALPC
Sequence: MSDTLLAFDFGTKSIGVAIGQRITGTARPLPAIKAQDGTPDWTLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVTVTLHDERLSTVEARSGLFERGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_LIMFE
Sequence: MRLTKREQEKMMISLAGMIAEKRKDRGLKLNQPEAVALITSRLLEGARDGKTVGELMNEGATWLTKDDVMEGIPEMIPMIQVEATFPDGTKLITVTDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ENTFA
Sequence: MSTVINGRELADQMQAEIQKDVEKMTQQGIQPGLVVLLVGENPASQTYVRNKERAAAKIGILSKVEKLPETISEEELLAEIDKYNQDSRFHGILVQLPLPKHIDEEKILLAIDPKKDVDGFHPMNLGRLFVGKPEMIPCTPYGIMKMFEAYDIDLTGKRAVVIGRSNIVGKPMAQLLLMKNATVTIAHSKTEHLAEVAKEADILVVAIGRGHFVTKEFVKPGAVVIDVGMNRNQEGKLIGDVAFDEVSEIASYITPVPKGVGPMTITMLMYQTVEAAKKQK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RR18_PLETE
Sequence: MKQPLKNTKRSNYKRKKRERVIALIPTKTNLTSPDKSLTPLPKEIIDYKNVILLRNGITAEGKIFPRRFTKLNAKQQRYMSKAIKNARMVGLLPFVKKSK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMN_PSESM
Sequence: MIASTGKTNLLGLTQQEMEKFFDSIGEKRFRAGQVMKWIHHFGVDDFDAMTNVSKALREKLKACAEVRGPEVVSEDISSDGTRKWVVRVESGSCVETVYIPQGKRGTLCVSSQAGCALDCSFCSTGKQGFNSNLTAAEVIGQVWIANKSFGSVPATVDRAITNVVMMGMGEPLLNFDNVIAAMHLMMDDLGYGISKRRVTLSTSGVVPMIDELSKHIDVSLALSLHAPNDALRNQLVPLNKKYPLKVLLESCRRYMSSLGEKRVLTIEYTMLKDINDKVEHAVEMIELLKDTPCKINLIPFNPFPHSGYERPSNNAIRRFQDLLHQAGYNVTVRTTRGEDIDAACGQLVGQVMDRTRRSERYIAVRELSADVDTAPAAATRT
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BURP1
Sequence: MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADEFAQRLAGASYEEIAQRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGERFPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAEQLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSPLTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVTVFTRDAR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLN3_MACFA
Sequence: MGGCAGSRRRLSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHERTSGNQSHVDPGPAPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVLASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESSARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCHIRFTWALALLQCLNLAFLLADVWFGFLLSIYFVFLIILYEGLLGGAAYVNTFHNIALETSDEHREFAMATTCISDTLGISLSGLLALPLHDFLCQLS
What is the function of this protein?
Mediates microtubule-dependent, anterograde transport connecting the Golgi network, endosomes, autophagosomes, lysosomes and plasma membrane, and participates in several cellular processes such as regulation of lysosomal pH, lysosome protein degradation, receptor-mediated endocytosis, autophagy, transport of proteins and lipids from the TGN, apoptosis and synaptic transmission.  Facilitates the proteins transport from trans-Golgi network (TGN)-to other membrane compartments such as transport of microdomain-associated proteins to the plasma membrane, IGF2R transport to the lysosome where it regulates the CTSD release leading to regulation of CTSD maturation and thereby APP intracellular processing (By similarity).  Moreover regulates CTSD activity in response to osmotic stress (By similarity).  Also binds galactosylceramide and transports it from the trans Golgi to the rafts, which may have immediate and downstream effects on cell survival by modulating ceramide synthesis.  At the plasma membrane, regulates actin-dependent events including filopodia formation, cell migration, and pinocytosis through ARF1-CDC42 pathway and also the cytoskeleton organization through interaction with MYH10 and fodrin leading to the regulation of the plasma membrane association of Na+, K+ ATPase complex.  Regulates synaptic transmission in the amygdala, hippocampus, and cerebellum through regulation of synaptic vesicles density and their proximity to active zones leading to modulation of short-term plasticity and age-dependent anxious behavior, learning and memory.  Regulates autophagic vacuoles (AVs) maturation by modulating the trafficking between endocytic and autophagolysosomal/lysosomal compartments, which involves vesicle fusion leading to regulation of degradation process.  Participates also in cellular homeostasis of compounds such as, water, ions, amino acids, proteins and lipids in several tissue namely in brain and kidney through regulation of their transport and synthesis (By similarity).
What are the official names of this protein?
Battenin, Protein CLN3.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome. Lysosome.
Protein: STP14_ARATH
Sequence: MAGGALTDEGGLKRAHLYEHRITSYFIFACIVGSMGGSLFGYDLGVSGGVTSMDDFLKEFFPGIYKRKQMHLNETDYCKYDNQILTLFTSSLYFAGLISTFGASYVTRIYGRRGSILVGSVSFFLGGVINAAAKNILMLILGRIFLGIGIGFGNQAVPLYLSEMAPAKIRGTVNQLFQLTTCIGILVANLINYKTEQIHPWGWRLSLGLATVPAILMFLGGLVLPETPNSLVEQGKLEKAKAVLIKVRGTNNIEAEFQDLVEASDAARAVKNPFRNLLARRNRPQLVIGAIGLPAFQQLTGMNSILFYAPVMFQSLGFGGSASLISSTITNAALVVAAIMSMYSADKFGRRFLLLEASVEMFCYMVVVGVTLALKFGEGKELPKSLGLILVVLICLFVLAYGRSWGPMGWLVPSELFPLETRSAGQSVVVCVNLFFTALIAQCFLVSLCHLKYGIFLLFAGLILGMGSFVYFLLPETKQVPIEEVYLLWRQHWLWKKYVEDVDE
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
What are the official names of this protein?
Sugar transport protein 14, Hexose transporter 14.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SODM_BORBU
Sequence: MFKLPELGYDYDAVEPYIDAKTMEIHHSKHHNGFVMNLNSILEKMGKIHLTDVSNILKNIHDFPEEFQTLIRNNAGGYSNHTLYFRTLRPGNKDNLFEKFKDDINAAFGSLDVLKANLKDTAMKIFGSGWAWLVLCPESGLKVISMPNQDSPLMNSYKPILGIDVWEHAYYLKYQNRRIEYVDAFLKALNWEEVSKVYNEVIN
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: NQO5_THET8
Sequence: MRLERVLEEARAKGYPIEDNGLGNLWVVLPRERFKEEMAHYKAMGFNFLADIVGLDYLTYPDPRPERFAVVYELVSLPGWKDGDGSRFFVRVYVPEEDPRLPTVTDLWGSANFLEREVYDLFGIVFEGHPDLRKILTPEDLEGHPLRKDYPLGETPTLFREGRYIIPAEFRAALTGKDPGLTFYKGGSRKGYRSLWADLKKAREVKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.  The Nqo5 subunit may be involved in the stabilization of the complex.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 5, NADH dehydrogenase I chain 5, NDH-1 subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEOB_STRTD
Sequence: MSKFNRMHLIVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKTVGLNVPNMAKLGLGNIPREQPLKTVPAESNPTGYATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTQIEEFSGRKVIRESNRPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPVEELYRICEFARSITLERPALLGRIIARPYVGEPGNFTRTSNRRDLAISPFAPTVLDKLNEAGIDTYSVGKISDIFNGEGINHDMGHNKSNNHGVDNLIKAMTSEDFKHGFSFTNLVDFDALYGHRRNPQGYRDCLHEFDERLPEIIAAMKEDDLLMITADHGNDPTYAGTDHTREYIPFLAYSPSFKCSGLIPVGHFADISATIADNFGVEKAMIGESFLDKLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_STRGC
Sequence: MSQGKIIKVSGPLVLASGMQEANIQDICRVGDLGLIGEIIEMRRDQASIQVYEETSGLGPGEPVITTGSPLSVELGPGLISQMFDGIQRPLERFQTITESDFLVRGVQLPNLDRETKWNFVPSLSVGDAVEAGDILGTVQETNLVEHRIMVPVGVSGRLANISAGSFTVEETVYEIEQAEGSIFKGTLMQKWPVRRGRPFAQKLIPVEPLVTGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPSTGQSIMQRTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRVKTLGSTAREGSITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAQLAQRRHFPAINWLSSYSLYLDEVGAYIDQHEKIAWAEKVTKAMNILQKESELQEIVRLVGLDSLSEKDRLTMNAAKMIREDYLQQNAFDDVDTYTSFKKQVALLSNILTFDAEANRALELGAYFREIMEGTVELRDRIARSKFVHEDQLEKIQALSQTIEETLHQILAQGGLDNERH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RS16_MESH2
Sequence: MVRIRLQRMGSKFNPFYKIVVADARAPRDGRFIEALGYYNPQQKFAKVNLEKTYRWLHIGAQVTQTVRNIFSKKGVFKNFLEQKSSRA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FTSQ_ACTPJ
Sequence: MIVLLCVIFAFLVYSNWHSWLESLDRNPIRAYALTHKTRFTTNADIRETLSQKPALKGYFGQDIQDVKAKLLAISWVRDVVVRKVYPDRLSITLIEHNPVAVWNDVNFLSEQGIVFSLPPDRIDKTGFPMLYGPDTEGKVVLEAWSKIKADLKARNLDLSSVSVDNRGSWTITLSNNVELRLGRGEWTPKIDRFVTIFPEIDVPEGKKLAYVDLRYEHGAAVGFSPLPK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: LEXA_XYLF2
Sequence: MSLSDIQQAILSLITNNINADGVSPSQTEIARAFGFKGVRAVQHHLDVLEQQGMIRRIPGQARGIRLKHLTEVDEVALALQSKDVLRLPVLGRVAAGQPIGADIGEDHVVLLDRVFFSPAPDYLLRVQGDSMRDEGIFDGDLIGVHRTQDAHSGQIVVARIDDEITVKLLKISKDRIRLLPRNPDFAPIEVRSDQDFAIEGLYCGLLRPNR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ISPG_WOLPM
Sequence: MLDKDLILNDNTCELSQISRHKTHVVEVGKVKIGGNNPVVVQSMALGVHIDADNIKSSAKHYAKEITELARTGSELVRIALNSEEVARAIPYIVEEINKEGFDGKILVGCGQYELDKLVQDYPDNIKMLGKIRINPGNIGFGDKRDEKFERVIEYAIMHDLPVRIGVNWGSLDKYLLQKLMDENSSLSNSRPSDVILRKALVMSALDSAKKAEEIGLNSNKIIISCKVSKVQDLILVYMALAKSSNYALHLGLTEAGMGNKGVVNTAAGLTYLLQNGIGDTIRASLTQRPGESRTNEVVVCQEILQSIGLRHFNPQVNSCPGCGRTSSDRFRILTEEVNGYIKTHMPMWKKKNPGVEHMNIAVMGCIVNGPGESKHANLGISLPGYGEKPVSAVYKNGKYFKTLQGDNVSEEFKAIIDNYVKKHYT
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CACB3_BOVIN
Sequence: MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGSRRSPPPSLAKQKQKQAEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYHDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHNERNWQRNRPWPKDSY
What is the function of this protein?
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:10684870).  Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (PubMed:10684870).  Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3.
What is the protein family that this protein belongs to?
Belongs to the calcium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_PSET1
Sequence: MIQMQTQLEVADNSGARKVQCIKVLGGSHRRYAAIGDIIKVSVKEAIPRGKVKKGDVKNAVVVRTKKGVRRPDGSLIRFDSNAAVILNDNLQPIGTRIFGPVTRELRNDKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DSG4_MOUSE
Sequence: MDWLLFRNICLLILFMVVLGVNSEFIVEVKELDIENGTTTWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVSQRITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIHCRALNSRGEDLERPLELRVKVMDVNDNPPVFTQNVYTANIEENSDANALVVKLSATDADEDNHLNSKIAYKIISQEPAGAPMFMVNRYTGEVRTMSNFLDREQHSMYNLLVRGSDRDGATDGLSSECDCRIKILDVNDNFPILEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYSILSGNDGNWFEIQTDPKTNEGILKVVKMLDYEQEPNIYLSIGVRNQAEFHHSVASQFQMHSTPVRIQVVNVREGPTFSPSSMTFSLRGGMRGASLMNYVLGTYTAIDMDTGNPATNVRYVIGHDAGSWLKVDSRTGEIQFSREFDMKSKYITDGIYAAQILAIDDGSGRTATGTICIEIPDANDYCPVIYAESRSVCTHASSVRIYVNDHSFGSPFTFCVVDESPDIANIWDIRSINGTSAILMTEQTLSPGPYQIPILVKDSHNRACELPQTVLLDACFCDDHHVCLHSSTTGIYTGDITWVTDDMYGTVTDDGVRQSNVGLGPAGIGMIILGLLLLLLSPLLLLMCCCKRRQPEGLGTRFAPVPEGGEGVMQPWRIEGAHPEDRDVSNICVPMTASNTQDRIDSSEIYTNTYAGGGTVEGGVSGVELNTGVGTATGMVAAGATGTLRKRSSTIGTLREYQDTGMNMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGAGSPVGSIGCCSWIVDDLDESYIETLDPKFRTLAEICLDTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGMTLSEAEFQAEMAAASEPMIHGDIIVTETYTTSDPCVQPTTIVFDSQIPPNVVVTETVMAPVYDVQGNICVPAEIANTHNVYYAERVVASPGIPDMGNSNISDACIGPVMSGGILVGPEIQVTQMMSPDIHISQTTGSTSPMTSQHRVTRYSNMHYSRQ
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.  Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes.
What are the official names of this protein?
Desmoglein-4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: GLNB2_METTH
Sequence: MIFMKEIVAIIRPEKLEEVKNALEAAGCHGMTVTEVRGRGRQLGITESYRGRDYRIDLLPKTKIEIVVNDEDVDTVVETIVKSAQTGDIGDGKIFISGVDEVVRIRTGESGKKAV
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen regulatory protein P-II 2.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: DXO_DEBHA
Sequence: MIKTFPLNSRAKTTALKQPKELFSFARDIDGEYIFDSTKVQDENLSYYYLPDASVDKQIDLGAGYSNFKKIPEEENLGDFPALLKGVMNYEQSTGTKINSDIITFRGLMTKILTLPYNLKDPLDLHVIVYDGQLFIKNNDEIELKRRQQNNQHEDPSKQEMMKKFEYSGYKFEAVSTLPKPWGDCSRQLIEKRNKKVVNNYEQYISVVKTGIGKVKLLLAGEVDCLWDYIPEDGKDILPHYVELKTSKVIEAPGQVVNFEKKLFRTWAQSFLIGIRKIVYGFRDDNLILRNVEVYNTEEIPIMLKDTINVNTKIVCMNALKWYGAVIEWINNEIPKDADKSWSLTYDPGSKSFSIVELMQDSELRNSVITEDFKEWRISLHKTES
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
What are the official names of this protein?
Decapping nuclease RAI1, NAD-capped RNA hydrolase RAI1, DeNADding enzyme RAI1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF1_SYNS9
Sequence: MDASTLTSRLQTATASFRSLERQLADPDVANDPKRLETIARERSRLEPLVLDFEALQKLEQEQADARELLRESRSDAAMQELAQDELSELEAQHTALLQRLTLALLPRDPRDDRSVMLEIRAGAGGDEACIWAGDLARMYERYGQKLGWSVQQLSCTEADLGGYRELIVSVKGTSVFSQLKFEAGVHRVQRVPATESQGRVHTSTATVAVMPEADAVEVELDPKDLEISTARSGGAGGQNVNKVETAVDLLHKPTGIRVFCTQQRSQLQNRERALEILRAKLLERELAAAAERESSHRRSQVGSGDRSEKIRTYNYKDNRTTDHRLGRNFSLEPVLQGQLEDLIGACIAEEQRQKLEALSEETDD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB191_ARATH
Sequence: MDSVNQRDRISSLPDVVLVMILSFLSFKDNVKTSILSKRWRNICYEAKNISFKESEYVDISVFDYVSKRVSFVRYMLNWVSRVPIKVIESFEICLGFPVGFEVEIKSLIEFSISRQVKKLVLDFSSPFWDNTWDGLRNDDFVIELPALIYGLQTLESLTIYACMFDPSRFTNVGLRTLSIGWFRLEKIESLLSKFPLLESLSIISCYLDEVKLAGQIRVRELIIDNCIIPTMYCLLNLPNIEIFKYSGNVIVFDFQKVNMILLKEVYLDFFIEHENDEPTYSPKEAGDILSHLLNDLRSSRTLTVCSYLLEVISECNDPVDMLRDVQAQHLVLETLMHPNEFTGMRLLLDHCPNLETLTFQLLCLKPFPVRLQYIDSHTLWLENISSRCLRRTLKILVVRGFCNSWNEFYLLNYLVLPEHGFALERVELYLPPLQEMPRQWAYHGAAMLQKTSNRVQVILHSA
What are the official names of this protein?
Putative F-box protein At3g29830.
Protein: RALA_HUMAN
Sequence: MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL
What is the function of this protein?
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking.  Accomplishes its multiple functions by interacting with distinct downstream effectors (PubMed:18756269, PubMed:19306925, PubMed:20005108, PubMed:21822277, PubMed:30500825).  Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles.  The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108).  Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor.  Required for anchorage-independent proliferation of transformed cells (PubMed:19306925).  During mitosis, supports the stabilization and elongation of the intracellular bridge between dividing cells.  Cooperates with EXOC2 to recruit other components of the exocyst to the early midbody (PubMed:18756269).  During mitosis, also controls mitochondrial fission by recruiting to the mitochondrion RALBP1, which mediates the phosphorylation and activation of DNM1L by the mitotic kinase cyclin B-CDK1 (PubMed:21822277).
What are the official names of this protein?
Ras-related protein Ral-A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cleavage furrow. Midbody, Midbody ring. Mitochondrion. Note=Predominantly at the cell surface in the absence of LPA. In the presence of LPA, colocalizes with LPAR1 and LPAR2 in endocytic vesicles (PubMed:19306925). May colocalize with CNTRL/centriolin at the midbody ring (PubMed:16213214). However, localization at the midbody at late cytokinesis was not confirmed (PubMed:18756269). Relocalizes to the mitochondrion during mitosis where it regulates mitochondrial fission (PubMed:21822277).
Protein: NRDR_LISMC
Sequence: MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREEFAREKVRRGLIRACEKRPVSAEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLDEVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS12_LISW6
Sequence: MPTINQLVRKPRQSKIKKSTSPALNKGLNSFKRELTDVNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRGQSRSKYGTKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.