PharMolix/UniProtQA huggingface dataset:
Protein: Y3012_BACCR
Sequence: MELNTMGKNHYKWSNKQLREHVEVLDGKRSTHILLKNATYLNSYMREWMTANIWIYNDRIVYVGEQLPEQLTECEVVDCEGKYVVPGYIEPHAHPYQLYNPETLANHAMQFGTTTFINDNLTLFFTLKREEAFRLLDEFNKIPASMYWWCRFDGQTELQNGESLFNSEEIIEWLQHEAVLQGGELTAWPKLLHGDDEMLTWVQETKRLQKKVEGHFPGASETTLAKLKLLGTDCDHEAMTGQEAFTRLMQGYTVSLRNSSIRPDLEVILKELLELGVKQFDRFFFTTDGSHPSFYENGMTNVMISTAIKQGVPVIDAYDMASYNIARYYNMEHVHGSIATGRIANINILESKENPVPISVLAKGKWVKRDGVNTHEALHIDWSKHKVTPLSLDWSIEKEDMIFSNKTGIHLLNNVITKPYTSEINIDCDELSTDHDECFFMMIARDGSWQVNIAVKGFAKELGGLASSYSGTGDIILIGKRKEDMLTAFRRVKELGGGMVIAEKNEVLHEIALPLLGIMSNLKMRELIQEEKQMVKLLQERGYAHDDPAFTILFFSATHLPFIRVTPIGLYDVKSSKVVAPPVNLIKQY
What are the official names of this protein?
Putative adenine deaminase BC_3012, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: MALX2_YEAST
Sequence: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
What is the function of this protein?
Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides.  Not required for isomaltose utilization, but overexpression allows the IMA1 null mutant to grow on isomaltose.
What are the official names of this protein?
Oligo-1,6-glucosidase IMA3, Alpha-glucosidase, Isomaltase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BORAP
Sequence: MERKVFSKDGKEIRTINLDDRVFNIEISHGSIYNAIKNELSNLRVGTSSTKTRSEVRGSSKKPWKQKGTGRARVGTRRNPVWIGGGIALGPKPRDYSYRLPKKVKRLAFKSVLSLRASDENNFKVIENFNIESGKTKDLALIIKNFASFNGKVVILLGNDDQMIKRAGKNIRDLKILSFDKLRVVDLFYAKNLIALESAVNKLNEFYVK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DPO3A_THEAQ
Sequence: MGSKLKFAHLHQHTQFSLLDGAAKLQDLLKWVKETTPEDPALAMTDHGNLFGAVEFYKKATAMGVKPIIGYEAYVAAESRFDRKRGKGLDGGYFHLTLLAKDFTGYQNLVRLASRAYLEGFYEKPRIDREILREHAQGLIALSGCLGAEIPQFILQDRLDLAEARLNEDLSIFGDRFFIEIQNHGLPEQKKVNQVLKEFARKYGLGMVATNDGHYVRKEDARAHEVLLAIQSKTTLDDPERWRFPCDEFYVKTPEEMRAMLPEAEWGDEPFDNTVEIARMCDVDLPIGDKMVYRIPRFPLPEGRTEAQYLRELTFLGLLRRYPDRITEAFYREVLRLLGTMPPHGDERALAEALARVEEKAWEELRKRLPPLEGVREWTAEAILHRALYELSVIERMGFPGYFLIVQDYINWARGHGVSVGPGRGSAAGSLVAYAVGITNIDPLRFGLLFERFLNPERVSMPDIDTDFSDRERDRVIQYVRERYGEDKVAQIGTFGSLASKAALKDVARVYGIPHKKAEELAKLIPVQFGKPKPLQEAIQVVPELRAEMEKDERIRQVIEVAMRLEGLNRHASVHAAGVVIAAEPLTDLVPLMRDQEGRPVTQYDMGAVEALGLLKMDFLGLRTLTFLDEARRIVKESKGVELDYDRLPLDDPKTFELLSRGETKGVFQLESGGMTATVRGLKPRRLEDIIALVSLYRPGPMEHIPTYIRRHHGQEPVSYAEFPHAEKYLRPILDETYGIPVYQEQIMQIASQVAGYSLGEADLLRRAMGKKRVEEMQKHRERFVRGAKERGVPEEEANRLFDMLEAFANYGFNKSHAAAYSLLSYQTAYVKAHYPVEFMAALLSVERHDSDKVAEYIRDARALGIPVLPPDVNRSGFDFKVVGEEILFGLSAVKNVGEMAARAILEERERGGPFKSLGDFLKRLPEQVVNKRALESLVKAGALDAFGDRARLLASLEPLLRWAAETRERGRSGLVGLFAEVEEPPLVEASPLDEITMLRYEKEALGIYVSGHPVLRYPGLREVASCTIEELSEFVRELPGKPKVLLSGMVEEVVRKPTRSGGMMARFTLSDETGALEVVVFGRAYEGVSPKLKEDIPLLVLAEVEKGEELRVLAQAVWTLEEVLEAPKALEVEVDHALLDEKGVARLKSLLDEHPGSLPVYLRVLGPFGEALFALREVRVGEEALGLLEAEGYRAYLVPDREVFLQGNGGGPKEEVVPF
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_STRPI
Sequence: MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQSKLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADASLQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVGQAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQELRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: YCF48_PROM9
Sequence: MKKIITSFPNLLLSILLCFVLSSCSSTGVKMSDSSPWKTIQFQDQANALDVDFIDNNNGFLVGSNRLIMESNDGGETWEKRNLDLPSEENFRLIDIDFKGQEGWLIGQPSLVMHTLDAGKNWTRLSLGNKLPGQPYLITTVDDGVAELATTAGAIYQTSDSGESWNAKVLDASGSGGVRDLRRTDKGDYVSVSSLGNFFSTLENDSNSWIAHQRASSKRVQSIGFNPEGSLWMLSRGAEIRFNEDTNDLENWSKPIIPILNGYNYLDMGWDPNGDIWAGGGNGTLIVSKDQGKTWNKYPIAAELPTNYIKIVFLDKEALDNQKGFVLGERGYILKWNS
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: PDUL_LIMRD
Sequence: MDEEHLRTLIRTIVRETLNPNLVPIGVSNHHVHLTEEDFQKLFPGQKIEMLKKLRQHADFAAKQTVDLIGPKGTIEHVRLMGPYRSHSQVEIARSENFTLGIDAPIRMSGDLDGTPSIKVRSPYAEIEIQGVIVAKRHIHMSLEDAKRFGVKLGDSMQVEVDGDGGRKTIFDDVVARPREDFVLEMHIDTDEANAANVGLGNNSFGKVIIKKKN
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: IDI2_STRR6
Sequence: MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLSTEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDSFSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRSWQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRRSGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTVLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMKKA
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RING1_BPCA1
Sequence: MVNNINWVKLPVILDRLLRHPLLTDLNLETAIQYTLDFISAMGLPNVYVDKIETIDIKEYRGELPCDLISINQVRLHKNGIALRAMTDNFNAYPTHDHKEGDWYERGEPSFKTQGRVIFTSIKHEKVDISYKAIMLDDEGLPLIPDNPIFLKTLELYIKKEWFTILFDMGKISPAVLNNTQQEYAFKAGQCNNEFVIPSVSEMEAITNMWNQLIPRVTEFRRGFKNLGDKEYIRVH
What is the function of this protein?
Forms the tail multi-ring barrel with ring protein 2, ring protein 3 and ring protein 4.
What are the official names of this protein?
Ring protein 1, R1, Gene product 43, gp43.
Protein: NIKR_KLEP7
Sequence: MQRVTLTLDDDLLAALDALSARRGYHNRSEAVRDILRDALNQDPPSPESRRGYAVLSYVYEHEKRELASRLVATQHHHHDLSVATLHVHISHDDCLEIAVLKGDMAEVQHFADDVIAQRGVRHGHLQCLADD
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: NIFB_HERSE
Sequence: MQPTQYVGIQDIKSLGTLLDKVAEHKGCGTSSEGGKASCGSSDGPADMAPEVWEKVKNHPCYSEEAHHHYARMHVAVAPACNIQCNYCNRKYDCANESRPGVVSEKLTPEQAAKKVFAVASTIPQMTVLGIAGPGDPLANPAKTFKTFELISQTAPDIKLCLSTNGLALPDHIDTIAAFNVDHVTITTNMVDPEIGQHIYPWIYYQNKRWTGIDAARILHERQMLGLEMLTARGILCKVNSVMIPGINDQHLVEVNRAVKSRGAFLHNIMPLISAPEHGTVFGLNGQRGPSAQELKALQDACEGEMNMMRHCRQCRADAVGLLGEDRSAEFTTEKIEAMEVAYDGATRKAYQELVEQERQAKSAAKAAEQQELAQMADQSGLSLLVAVATKGQGRVNEHFGHVSEFQIYEVSSAGSKFVGHRRVDQYCQGGYGEEDALETVIRAINDCHAVLVAKIGGCPKDDLQKVGIEPVDRYAHEFIEQSVIAYFMDYLERVRSGQIEHRPRGDADIRQGAYTSVQSTSAAA
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: SOML_CYCLU
Sequence: MHLVSVIQRGVWAVLLWPNLLASSVPLDCREEQGILSRCPSISQEKLLDRVIEHAELIYRVSEESCSLYEDMFIPLQFQRNQVGYACITKTLPVPSSKNEIQQISDKWLLHSVLMLVQSWIEPLVYLQTSLDRYNAAPEMLLNKTKWVSEKLISLEQGVVVLIKKMLDEGMLTINHSEQGLLQNGVQPQMLESVMRDYTLLSCFKKDAHKMEAFLKLLKCRQTDRYNCS
What are the official names of this protein?
Somatolactin, SL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GAF1_SCHPO
Sequence: MDLKFSNFFKEAEHPALVKKFDKSTTDESSSKEDYSTMSDLWKMFSKAKSELSNGRRVENLTWRLMSINLQKNLTPNGDSNTLTPDTFSDPTAPSSAQSVPPTSSAETTADNSDTEMKLNPIPAYSVPADTTGSSLMEFNYIQRRVRKTSFDESTAKSKKRSIADSHFPDPNAMQRPHDLESQPFSYPKIHASNSFNFVKRDIDSSNFSNLDASALPISPPSDFFSVHSHNLPNAPPSIPANSNNSASPNQRIKASPKHADTDVLGLDFDMTPSEPSSFPENGGFPSFVDANTHEQTLFPSSATNSFSFEHGSAGFPIPGSVPSTSYHANTASEDGFSSSYNSQGLFGISSPLSSGVTPNQSFFPDVSGNNIFDVSRNNHEVSSPLIQSPGSYVSMPSINMVSSLPISAPVPNSNSQFPRRPNTFRTNSSKSVGQGSSGVDSNQENAESFNPSISSHNSAEWASGETTGHSSNSPLPGSDMFSPQFMRVGTAMGVAPVRSNSSNNFGQNFFHQTSPQFSAVPHRKVSAQDTNLMGSSPGMYNHMPYLNRATSANSITSPGVLPEGMAASLKKRTTNTAATPQAALPTTLDTKKDRSVSFNINKNAEKPTVSNAAEDKKGDANTRRANATNPTPTCTNCQTRTTPLWRRSPDGQPLCNACGLFMKINGVVRPLSLKTDVIKKRNRGVGTSATPKQSGGRKGSTRKSSSKSSSAKSTAADMKPKADSKSISPGFVGGNQSLSSERIPLDPSMRSPLQQQSSENESKSQSMLSANNLNAGVNDFGLGFSEGLGSAHLDSNDSSMVQGKNDFAPVVDSPLFDAFDTDLGMSSVAESHTMNMDPSDLSRVSKSWDWYSVM
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Transcription factor gaf1, Gaf-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYYC_NOSCE
Sequence: MDTTEKLKLINRNLKEVIGGDIMEKIINKRDLNVYWGTATTGKPHIAYFLPILKIKDFVDAGCNVTILLADIHAFLDNLKAPIEKIECRSQYYKKIITLMLKSIKVDVSKISFIFGSEYQKSNKYFTDILRILNQTKKNDARRAGSEVVKQVKNSKLSSLVYPAMQALDEEYLNVDVQFGGIDQRKIFMYAREFLPLLKYKKRIHLMNPMIPGLNSDKMSSSDIDSKIDLLDTKLEIYKKIHNCSLENEGLIFLFKSIIYPYCSIFNLQIMISGKVYTFDKLYEDIKMKIIDETELKNIASDMIERLICPIRDEMLRDLKLIENAYGNK
What are the official names of this protein?
Probable tyrosine--tRNA ligase, cytoplasmic, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_KLEP3
Sequence: MSKSENLYHAARELIPGGVNSPVRAFTGVGGTPLFIERADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAASRGLSFGAPTEMEVKMAELVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQDIACIIVEPVAGNMNCIPPQPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQAYYGVEPDLTCLGKIIGGGMPVGAFGGRREVMDALAPTGPVYQAGTLSGNPIAMAAGFACLSEVAQPGVHETLTELTNQLADGLLNAARETGIPLVVNNVGGMFGIFFTDAETVTCYQDVVKCDVERFKRFFHLMLEEGVYLAPSAFEAGFMSIAHSEEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSMR_STRMU
Sequence: MNILNIYNEFDINNFDLSVDHYGSEKCDRGYSFGPTIRDNYVIHFILEGKGKLTINQHTLDLAAGDIFLLPKDISTFYQADLQMPWSYIWIGFSGSKAENILKQSSLFKRFYCHSGRSSKLFSQMMTIIQFANTPLTSVNELLMVGELYKLLAALIEEFPLSHLEESNSSTKAYVNQVKKIIHSQYGSSLRVNDIAKKLNLSRSYLYKIFRKSTNLSIKEYILQVRMKRSQYLLENPKLSIAEISNSVGFSDSLAFSKAFKNYFGKSPSKFRKEIQNN
What is the function of this protein?
Regulatory protein for the msm operon for multiple sugar metabolism.  Activates the transcription of the msmEFGK, aga, dexB and gftA genes.
What are the official names of this protein?
Msm operon regulatory protein.
Protein: DDL_ARTS2
Sequence: MSEEQLNKHTAPGHAKPRVAVLFGGRSSEHAVSCVTAAGVLGAIDYDKYDVIPIGIAKTGQWVLVSGDTRQWSLSASSLPEVSPSARTVTLAEIGGEHQLIVASPNEVPQELGAVDVVFPLLHGPFGEDGTIQGLLELSDTRYVGAGVLASAVGMDKHYMKVVFEAAGLQVGPYIAVTDRQWLTDPEAIRKRVDRLGYPVFVKPARAGSSMGISKVDSLEGLDAAIAAAREHDLKLVIEAGIVGREIECAVLEGRGTEPPRTSMPGEIAVAPGEHEFYDFNAKYVEDDAASLSCPADLPDEAIARVRELAAAAFDAVGAEGLSRVDFFYTPDGELIINEINTMPGFTPKSMYPQMWAASGLGYAELIDELIYLALNRKTGLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_HAEIG
Sequence: MAFNMKNRHLLSLVHHTEREIKYLLDLSRDLKRAKYAGTEQQKLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSSQIGHKESMKDTARVLGRMYDGIEYRGFKQSIVQELADYAGVPVFNGLTDEFHPTQMLADVLTMIEHCDKPLSEISYVYIGDARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTEDIDKAVKGVDFVHTDVWVSMGEPLETWGERIKLLLPYQVTPELMKRTGNPKVKFMHCLPAFHNSETKVGRQIAEKYPELANGIEVTEEVFESPMNIAFEQAENRMHTIKAVMVASLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS52_HUMAN
Sequence: MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMGRTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545).  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 52 homolog, SAC2 suppressor of actin mutations 2-like protein.
What is the protein family that this protein belongs to?
Belongs to the VPS52 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex (PubMed:25799061).
Protein: RBL_BARPR
Sequence: VGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVAGETDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIIMFDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAAEGNAIIREASKWSPELAAACEVWKEIKFEFKAVDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TCPH_DICDI
Sequence: MSQMIRPPIVLLKEGTDTSQGLPQLISNINACCAIVDTVRTTLGPRGMDKLIYQSERQVTISNDGATVMKLLDIVHPAARTLVDIAKSQDSEVGDGTTSVVILAGEFLKAAKPFLEEGIHPQIIIRAFRSACELAKQKIQELSVDIKPENMREFLEKCASTSMNSKLIASHKQFFSKMVVDAVQLLDDNIDLDMIGIKKESGGGLGDSQFIAGAAFKRTFFYAGFEQQPKHIKNPKVLCLNIELELKAEKDNAEIRISDPTKYQSLVNAEWKLFFDKLEAIHASGVNVVLSKLAIGDLATQFFADKNMFCAGRVPDDDIRRVCRATGAAIQNTTSNIIPDVIGTCDLFEEVQVGGQRYNLFTGCTMTQTATIILRGGGEQFIDEAERSLHDSIMIVRRARKHRSVVAGGGAIEMEVSKYLRDYSLSIEGKKQLLINAFAKALEVIPRQIADNAGFDSTDILNQLRQKHAQGEKWFGVDIVNEGICDTYESAIWEPSLVKLNSIVAATEATCLILSVDETVQNNQAEQAQAGPQINNQTRQALSRGRGVQAMRGRG
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit eta, TCP-1-eta, CCT-eta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM234_DICDI
Sequence: MDTYNIISLLLVGFIWGGTNPLIKRGSEGVSKVKKDNFLSQIIYEFVYLWTRPSYTIPMLINLSGSVVFFYTLSKVDISLVVPISNSLTFLFTSLMGMLLGEKVLHFKSYLGMIFVLAGVTICVSSKF
What are the official names of this protein?
Transmembrane protein 234 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM234 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IRAD_SALEP
Sequence: MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPEP3_RAT
Sequence: MQPTGPEGPRALSLRPLGHRLSLLGVLLIIPSLWVTCNQTTPSLSSAPTSPGASSAMTTPGIPNDTTTSGVTSDPRLREQALALMRDFPLVDGHNDLPLLLRELFQNKLQDVNLHNFTRGQTSLDRLRDGLVGAQFWSAYIPCQTQDRDAVRVALEQIDLIRRMCSAYPELELVTSADGLNSTQKLACLIGLEGGHSLDTSLAVLRSFYELGVRYLTLTFTCSTPWAESATKFRHHFYTNISGLTSFGEKVVEEMNRIGMMIDLSHASDTLVKQTLEASRAPVIFSHSAARSVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCSLLANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLLEELLRRGWGEQELQGVLRGNLLRVFRQVEQVREKSLGQSPVEVVFPERQQSSTCHSHLLPQSQDAHLKVTKLPSSQVLQRASKAPPCPLLGLVAAVTSPAFTLWLCCSGHR
What is the function of this protein?
Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem (By similarity).  The absence of activity may be due to the inability of serine (instead of aspartate found in DPEP1/2) at position 356 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide (By similarity).
What are the official names of this protein?
Dipeptidase 3.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor, GPI-anchor.
Protein: NAGS_YEAS1
Sequence: MWRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLHKVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNIPHIDKFFILNNAGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLTKREPRSQNLLHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNPLVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNAAPSNSDAVLVTTVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSPKLDINKFKSIIDQSFKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLGISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLFYYGNPQYAKRALRDKKRLREFMRSVRDIKPSWENEKNIS
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYQ_XYLFT
Sequence: MSEITTTDAQAQPEKKDFIRQIIREDLAHGTHTHIHTRFPPEPNGYLHIGHAKAICLDFGVAAEFGGHCTLRMDDTNPSKEDPAFAAAIQEDVSWLGFHWNALRHTSDYFEVLYLAAEKLIADGKAYVCDLNSQQVREYRGTLTEAGRPSPWRERSPDENLELFRQMRAGTFPDGTRTLRAKIDMASGNINLRDPALYRIKHVEHQNTGNTWPIYPMYDFAHALSDAIEGITHSLCTLEFEDHRPLYDWCINHVDLPNNSHLLKPLLDKGFPQEPSQPRQIEFSRLNINYTVMSKRKLTALVDEKLVEGWDDPRMYTLQGLRRRGYTPAAMRLFVERIGISKQNSIIDFSVLENCLRENLDTIAPRRMATIAPMKLVLTNLAEDHEEQLIFPNHPKDDTQGTRTVPFSRELWIERDDFSEAPPKGWKRLIPGGEVRLRGAGIARIDEVVKNAEGHVIALHGWLDPTSRPGMEGAHRKVKGTIHWVSAPHAVAAEIRLYDRLFSIEKPDDNTDGKTYRDFLNPDSKRVVHGYIEPAAAQTAPEHAFQFERLGYFVTDRHDHDATHPVFNRSVTLRDTWQRD
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.