PharMolix/UniProtQA huggingface dataset:
Protein: MENH_ECODH
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: AT1A_HYDVU
Sequence: MADPGDLESRGKADSYSVAEKKSAPKKISKKNANKAKLEDLKKELEMTEHSMKLESLLSMYETSLEKGLSENIVARNLERDGLNALTPPKQTPEWVKFCKQMFGGFSMLLWIGAILCFFAFGIRAVRDTNPNMDELYLGIVLSVVVIITGCFSYYQESKSSKIMESFKKMIPQEALVLRDGKKITINAEQCVVGDVVFVKFGDRIPADIRIVECKGLKVDNSSLTGESEPQSRAVDFTHENPIETKNLAFFSTNAVEGTATGIVVRIGDNTVMGRIANLASGLGSGKTPIALEIEHFIHIVTGVAVFLGVSFLIISLAMGYHWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKKMAKKNCLVKHLEAVETLGSTSVICSDKTGTLTQNRMTVAHMWFDKMIVEADTTEDQSGIAHDKGSLTWKSLAKVAALCSRAEFKPNQNDVAVLRKECTGDASETAILKFVELSVGNVMDIRAKNKKVTEIPFNSTNKYQVSVHEQENSSGYLLVMKGAPEKVLERCSTILINGEEQPLKDDVIEIYNKAYDELGGLGERVLGFCHYYLPVDQYPKGFLFKTEEEQNFPLEGLCFLGLLSMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNECEEDIALRLNIPLEDLSEDQKKSAKACVIHGAKLKDIKNEELDKILCDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIVYTLTSNIPEISPFLMFILFGIPLPLGTITILCIDLGTDMVPAISLAYEKAESDIMKRHPRNPIRDKLVNERLISLAYGQIGMMQATAGFFTYFIILAENGFLPSYLFGLRSQWDDMSNNNLLDSFGSEWTYFQRKEIELTCQTAFFTTIVVVQWADLIISKTRRLSLFQQGMTNWFLNFGLFFETALAAFLQYTPGVNTGLRLRPMNFTWWLPGLPFSLLIFVYDEIRRYLLRKNPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha, Na(+)/K(+) ATPase alpha subunit, Sodium pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COPZ_ENCCU
Sequence: MNLFDIEGLLVADSQGEILYRRVFSKEEEIAAKIAEKAAGDRESISMFYDRIVMCKRLDEVLLIIYSPMDVNEPFVGQVFDEFTAAFIGIVKTPTRERVWKKYDQIVLLVAEFLYEGIVMSGKSDEMLDKLPKRNFEGVDGMKVPRGFASFLHKATKSLSIGSNK
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta, Zeta-coat protein, Zeta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: BGLF_ASPFU
Sequence: MRVLSAIALVASLASSALSAPASESRVSTQLRSRDAEGYSSPPYYPAPNGGWLSSWADAYEKAQRVVRDMTLAEKVNLTTGTGIFMGPCVGQTGSALRFGIPNLCLQDSPLGVRNSDHNTAFPAGITVGATFDKDLMYARGVELGKEFRGKGINVLLGPSVGPIGRKPRGGRNWEGFGADPSLQAIGGAQTIKGIQSQGVIATIKHYIGNEQEMYRMSNVGQRAYSSNIDDRTLHEVYLWPFAEGIRAGVGAVMTAYNEVNSSACSQNSKLLNEILKDELGFQGFVMTDWLGQYGGVSSALAGLDMAMPGDGAIPLLGTAYWGSELSRSILNGSVPVSRLNDMVTRIVAAWYKMGQDGEFPLPNFSSNTQDATGPLYPGALFSPSGVVNQYVNVQADHNITARAIARDAITLLKNDDNILPLKKDDALKVFGTDAGPNPDGLNSCADMGCNKGVLTMGWGSGTSRLPYLVTPQEAIANISSNAAFFITDNFPSNVAVSSGDVAVVFISADSGENYITVEGNPGDRTSAGLNAWHNGDKLVKDAAAKFSKVVVVVHTVGPILMEEWIDLPSVKAVLVAHLPGQEAGWSLTDVLFGDYSPSGHLPYTIPRAESDYPSSVGLLSQPIVQIQDTYTEGLYIDYRLFLKANITPRYPFGHGLSYTTFSFSQPTLSVRTALDSTYPPTRPPKGPTPTYPTAIPDPSEVAWPKNFGRIWRYLYPYLDDPASAAKNSSKTYPYPAGYTTVPKPAPRAGGAEGGNPALFDVAFAVSVTVTNTGSRPGRAVAQLYVELPDSLGETPSRQLRQFAKTKTLAPGTSETLTMEITRKDISVWDVVVQDWKAPVRGEGVKIWLGESVLDMRAVCEVGGACRVI
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase F, Beta-D-glucoside glucohydrolase F, Cellobiase F, Gentiobiase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSH_SHESH
Sequence: MSNIPAELKYASSHEWIRKEEDGSYTVGISEHAQELLGDMVFIELPDVGDTLSAGEDCAVAESVKAASDIYAPLSGEVLAINEALEDSPELVNSDAFGDGWFFRVMPSDVAEIDSLLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: UFM1_MACFA
Sequence: MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC
What is the function of this protein?
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer.  The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.  Ufmylation of TRIP4 regulates nuclear receptors-mediated transcription.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EFTS_CERS4
Sequence: MAITAQMVKELRESTGAGMMDAKKALTETDGDMEAAVDWLRTKGLAKAAKKAGRTAAEGLVGVCVDGGTGVAVEVNSETDFVAKNADFQSMVTGFTKAALTVDDIEALKAADMGGKTVETTLQETIAVIGENMTLRRMAKISGDSVAAYVHNAAADGLGKIGVLVAVKGADNGIAKQVAMHIAATNPMALSEADLDPTVVERERTVQTQKALEENAASAKPKPDAVIENNIIPGRMKKFLEENTLLGQKFVINPDLTVAEAAKQAGVEIVGFVRMAVGEGIEKEKEDFAAEVAKTLAG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_THEFY
Sequence: MTMTDPIADMLTRLRNANAAYHETVAMPYSKIKAHIAEILQKEGYIQGWRVEDARVGKNLVVTLKYGPTRERAIAGLRRVSKPGLRVYAKKDNLPRVLGGLGVAIISTSSGLMTDKEAKKNGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PGP_PYRIL
Sequence: MKCKILVADLDGTLTLSRNTYELSVEALLALRKARDSGLRVVLATANGLDFALTIARYLGVRDVIAENGCLIHLDGVTYELCSGDMSIVDKVIISTGAVIPSPQNRCRKYDMAYIPLVKDTLEKVRAVVGTGYIVESSGYAIHVRPAGVDKGVAVSWLCRKLDVSCHQVATVGDSDVDVGMLSIAWGIAVGNATEAAKKAARVVVEEPSGLGFKEAVNLILSGDACTP
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: G3P1_GIAIN
Sequence: MPIRLGINGFGRIGRMALRASLNIDGVQVVAINDPFTDCEYMEYMLKYDTVHGRFDGTIAHSEDSITVNGNKISVFKSMKPEEIPWGKTQVDIVLECTGRFTTKKDAELHITGGCKRVIISAPSADAPMFVCGCNLETYDPSTMKVISNASCTTNCLAPLAMVVNKKFGIKEGLMTTVHAVTATQLPVDGPSKKDWRGGRSCGANVIPSSTGAAKAVGKVLPALNGKLTGMAFRVPVPDVSVVDLTCTLEKDATYDEICAEIKRGSENELKGIMTYTNEDVVSSDFLSTTSTCNFDSKAGIMLNSRFVKLVAWYDNEFGYANKLVELAKYVGSKGCQ
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_ACIB3
Sequence: MSKHTVLFELGCEELPPKSLKTLRDALQAETVKGLNEAGLNFASVEAYAAPRRLALKIVDVDAAQADTQKRFDGPAVQAAYDAEGKPTKALEGFMRGQGITVEQLSTFQAGKVEKVCYLKDVKGQSLDTLLPQILQTALDNLPIAKRMRSAASRTEFVRPVKWVVLLKDDQVIEATIQDHKAGNVTYGHRFHAPEAVTLAHANDYLAALEKAYVVANFEKRQATIQEQVKKLADEVNATAIVPADLLDEVTSLVEWPVALRATFEERYLAVPQEALITTMQDNQKYFCLINAEGKLQPYFITVSNIESKDPTQIIEGNEKVVRPRLSDAEFFFLQDQKQPLASRKEKLANMVFQAQLGTLWDKSTRIAKLAVALSSITGANPADAEKAALLAKCDLTSELVGEFPELQGIAGTYYARIEGENTEVSEALGEQYLPKFAGDVLPKTKTGTTIALSDRLDTLVGIFGIGQAPTGSKDPFALRRSAIGILRLIIENELDVTIEELVNLALQGYGDIVKDHDKTRADAVAFLEGRYRAKYEDQGVAVDVLQAVQALAPKSPLDFDKRVNAVNHFRTLPEAAALAAANKRVANILAKEATPEGSVVEANLVEDAEKALFAELQAVTPVVEPLLAAKDYTAALSKLAALRAPIDAFFDGVMVMADDAGLKANRLRLLAQLRNLFTAVADVSVLQG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_DESAH
Sequence: MVELDFNKTGGLIPAIAQDHETGEVLMLAYMNEAAWNKTLESGMATYFSRSRQSLWKKGETSGHVQVVKEIRIDCDNDTVLLKVEQKGGAACHLGYKSCFFRRVVKGDDPVIMEQQIFDPKKVYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIB37_BPAR1
Sequence: MATLKQIQFKRSKTAGQRPAASVLAEGELAINLKDRVLFTKDDQGNIIDLGFAKGGSIDGNVIHKGNYNQTGDYTLNGTFTQTGNFNLTGIARVTRDIIAAGQIMTEGGELITKSSGTAHVRFHDSADRERGIIFSPANDGLTTQVVNIRVRDYKASSESTFAFNGNGLFSSPEVFGWKSVSTPVIYTNKVITNKKVKDDYDIYSMADNVPLSEITTAINHLRVMRNAVGSGIFHEVKDNDGITWYSGDGLDAYLWSFTWSGGIKSSHSISIGLTPGPKDYSILGPSSIALGDNDTGFKWHQDGYYFSVNNGTKTFLFSPSETTSLRKFVAGYSTNGTDLTTPPTENYALATVVTYHDNNAFGDGQTLLGYYQGGNYHHYFRGKGTTNINTHGGLLVTPGIIDVIGGSVNIDGRNNASTAMFKGNTTGSSSVDNMTISVWGNTFTNPSEGNRKNVMEISDATSWMSYIQRLTTGEVEMNVNGSFESSGVTAGNRGVHTTGEISSGAVNALRIWNADYGVIFRRSEGSLHIIPTAYGEGKNGDIGPLRPFSIALDTGKVVIPDLESSYNTFAANGYIKFAGHGAGAGGYDIQYSQAAPIFQEIDDAAVSKYYPIVKQKFLNGKAVWSLGTEINSGTFVLHHLKEDGSQGHTSRFNADGTVNFPDNVQVGGGEATIARNGNIFSDIWKTFTSAGETTNIRDAIATRVSKEGDTMTGKLTLSAGNDALVLTAGEGASSHIRSDVGGTNNWYIGKGSGDNGLGFYSYITQGGVYITNNGEIALSPQGQGTFNFNRDRLHINGTQWTAHQGGGWENQWNQEAPIFIDFGNVGNDSYYPIIKGKSGITNEGYISGVDFGMRRITNTWAQGIIRVGNQENGSDPQAIYEFHHNGVLYVPNMVKAGARLSAGGGDPVWQGACVVIGDNDTGLVHGGDGRINMVANGMHIASWSSAYHLHEGLWDTTGALWTEQGRAIISFGHLVQQSDAYSTFVRDVYVRSDIRVKKDLVKFENASEKLSKINGYTYMQKRGLDEEGNQKWEPNAGLIAQEVQAILPELVEGDPDGERLLRLNYNGVIGLNTAAINEHTAEIAELKSEIEELKKIVKSLLK
What is the function of this protein?
Structural component of the distal-half tail fiber.  It constitutes the part of the long tail fibers that recognizes the bacterial receptor (By similarity).
What are the official names of this protein?
Long tail fiber protein p37, Protein Gp37, Receptor-recognizing protein.
What is the protein family that this protein belongs to?
Belongs to the tail fiber family.
What are the subcellular locations of this protein?
Virion.
Protein: PCNA_META3
Sequence: MFKAVMNAKNFKKIIDSISNLVDEICFEVDELGIKANAMDPSHVALISVNIPKESFDEYVSDTHDIGVDLEALKKIMNRAKPNEKLMLELDMEKNKLDIILKNEGTRKFSISLYDVSSSNVKVPEIGYPNEVMIKAGTIVESLKDAELVNDHVSLKITEDGKFIIYSKGDINTNETVLDRDNESIIELKISESSKSTYNLAYLKDITKATSSEDILHIHLGTDMPVKIEYIIGDTKLIYLLAPRIES
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: SFSA_SYNJB
Sequence: MECGDGPVPYRFSSPLHRGVLRSRYKRFLADVELENGQQIIAHCPNTGPMSGVCQVGAPVYLSHHPEPKRKLAYTWEMIQVDGVWVGINTSLPNRLVDWGLERGWFPQLAGFSRRQREVTCGKSKIDFLLTGDAGSAYLEVKNTTWAVGSRALFPDTVTTRGQKHLEDLIQIRQQGQRALLLYWINRADCTEFAPGEERDPRYARLFREALQAGVEMLPYRVEVSPTGIRPLGLAKIVV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RSMG_VIBPA
Sequence: MSALRTKLDSLIAQTDLDVSEKQREQLVGYVELLDKWNKAYNLTSVRDPLEMLVKHILDSIVVGTHLQGERFIDVGTGPGLPGIPLAIMHPEKTFFLLDSLGKRIRFIKQVVHTLGLKNVTPIQSRVEEFQPEEKFDGVLSRAFASMTDMVEWCHHLPKEQDGVFLALKGQHPKDEMDLLPEWCSVTEIISLAVPELEGDRHLVILSRKEN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_STRZP
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RS13_ANADE
Sequence: MARIAGVDLPREKRIEVSLQYIYGIGKTSAKLILERANVSPVTRTKDLTDDEVRRIRETIEQNVKVEGDLRREISLNVKRLMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPKKGLVRKAAAPAPKA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS3A_DROPS
Sequence: MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKTTEAVVSAEGAVVDRPEGYEPPVQEAV
What is the function of this protein?
Essential for oogenesis; required for late follicle cell development.
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_VIBPA
Sequence: MKQILDFIPLIIFFALYKMYDIYVATGALIVATAVQLIVTYALYKKVEKMQLITFVIVTIFGSMTIFFHDDNFIKWKVTIIYVVLAVGLTASHLMGKSVVKGMLGKEITLPDAIWAKINWAWVGFFSFFAGLNIYIAYELPLDVWVNFKVFGMLIATFAYMIATGVYIYKHMPKEEKNNSSDVSVDD
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYC_ALISL
Sequence: MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYDLTFVRNITDIDDKIIKRAAENNESCEALTERLIAEMHADFDALKMKRPDVEPRATEYITEIVELVERLIERGFAYVASNGDVMFEVKKFDEYGRLSRQDLEQLQAGSRVTLEETSVKRSGMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLMFPHHENEIAQSCCAHDAKYVNTWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHYRSQLNYSEENLNQARSSLERLYTSLRGLDLTVTPAGGETFVTRFSTAMNDDFNTPEAYSVLFEMAREVNRLKTENIEAASKLGALMRELAEVLGLLSQEPEAFLQGDSGSDNEVAEIEALIKARNDARAAKDWSAADAARDAITALNIVLEDGPEGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_STUS1
Sequence: MANSPSAKKRAIQAEKRRSHNASLRSMVRTYIKNVVKAIDAKDLDKARAAYTAAVPVIDRMADKGIIHKNKAARHKSRLNGHIKALGEAAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DNLJ_SALCH
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYRNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAEGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAEESNRDVIVQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: KTHY_SYNR3
Sequence: MRGRFLVLEGIDGCGKTTQLKALADWLPASGLMPSGAQLITTREPGGTALGQALRQLLLHPPEEQAPATRAELLLYAADRAQHVQTRLEPALAAGDWVLSDRYCGSTAAYQGYGRGLDLDLITQLEQLATAGLQPDLCLWLELSPELAAQRRSGQQQDRIEAEGLAFLARVHQGFAELSQRPLWRRVDASLPPEQVHQQVQHLVREGLELAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YH20_RHOCA
Sequence: MSSSPGRIDADLAGGFGHDLVTLTELQFRQVEGALTAAGLDEAVLLGFNRLRLGVVEQAAALGQLIEEGARQQADLEAMHRLLRDAPVPILSIDATLGLHYSNEAARRFLGESFEQNGGAALRRSLTRPQIGRLSAALARAGDPAGRRRRI
What are the official names of this protein?
Uncharacterized 16.1 kDa protein in hypE 3'region, ORF20.
Protein: RRF_BREBN
Sequence: MPQTVLNDMEDRMNKAINALKRDLSSLRAGRANPAMLDRVTVDYYGTPTPISQLANISVPEPRMLTIQPWDKTALKEIDRALQQSDLGISPSNDGVIIRLIIPPLTEERRKELVKLAGKGGEEAKVAIRNIRRDANDEIKKLEKAATISEDDSRRHQETIQKTTDKFIAEVDKIVKDKEKDILEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_BACSU
Sequence: MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGFRKGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESLIFTAKVTVKPEVKLGEYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAVEEGNTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVTFPEEYHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRLEEAKENEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELYTQFSGQDEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNMPVENIKQAIGSTDAMKEDLKVRKAIDFLVENR
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase, Vegetative protein 2, VEG2.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CLPX_CLOK1
Sequence: MKMAKNDDKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIISDEFEEDIQIDMTSIPKPVEIKNYLDQYVIGQEDSKKSLSVAVYNHYKRINSNNNSNDDVELQKSNILLLGPTGSGKTLLAQTLARFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDIERAEHGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTTNILFICGGAFDGIDSIIERRTRVSTLGFGAEIQSKKDKDIGKLLKQIMPGDLLKFGLIPEFVGRIPIIVTLEALDRAALISILKEPKNALVKQYKKLFELDDVELEFKDEALEAIADEALKRNTGARGLRAIIEETMKDVMFDIPSKEEIAKVIINKDAVSTKMPELIEAENGKRTPIKLKKSRTRKGPETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YHBQ_ECOSM
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPKIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RL7_TERTT
Sequence: MALSKEDILNAIAEMSVMDVVELVEAMEEKFGVSAAAAVAVAAPAAGDAGAAAAEEQTEFDVVLASAGEKKVNVIKAVRAITGLGLKEAKAMVDGAPSTVKEALSKDDAEAAKKELEEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.