PharMolix/UniProtQA huggingface dataset:
Protein: MCM4A_XENLA
Sequence: MSSPTSTPSRRKSKRGRGSNPPTPRGEEVQSPPSQKRRTEDSTSIGELLPMPTSPSGDIQSPLFSSPAPSRHSAHQSELDLSSPLTYGTPSSRVEGTPRSGIRGTPARQRADLGSARKVKQVDLHSDQPAAEELVTSEQSLGQKLVIWGTDVNVAICKEKFQRFVQRFIDPLAKEEENVGLDLNEPIYMQRLEEINVVGEPFLNIDCDHLRSFDQDLYRQLVCYPQEVIPTFDMAANEIFFERYPDSILEHQIQVRPYNALKTRNMRSLNPEDIDQLITISGMVIRTSQIIPEMQESFFKCQVCAFTTRVEIDRGRIAEPSVCKHCNTTHSMALIHNRSMFSDKQMIKLQESPEDMPAGQTPHTTILYAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVRNVKSVYKTHIDVIHYRKTDSKRLHGIDEDTEQKMFTEERVAVLKELAAKPDIYERLAAALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEVNILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPVESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDETYDRRLAHHLVALYYQSEEQLKEEHLDMAVLKDYIAYARTYVNPRLGEEASQALIEAYVDMRKIGSGRGMVSAYPRQLESLIRLSEAHAKVRFSSKVETIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATARKRKEELAQVLKKLIQSKGKTPAFKYQQLFEDLRGQSDAAITKDMFDEALHALADEDYLTVTGKTVRLL
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor mcm4-A, CDC21 homolog-A, Minichromosome maintenance protein 4-A, xMCM4-A, P1-CDC21-A, p98.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: DAPB_STAAR
Sequence: MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSNPNLLFPLLDEAFHLPLVVATTGEKEKLLNKLDELSKNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_SHEB9
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARPFNVTGHQNAQGGYGAQDDAPSGE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: NODE_RHIME
Sequence: MDRRVVITGMGGLCGLGTDTTSIWKWMREGRSAIGPLLNTELHGLKGIVGAEVKALPDHNIDRKQLVSMDRISVLAVIAAHEAMRQAGLSCNEGNALRFGATVGVGLGGWDATEKAYRTLLVDGGTRTEIFTGVKAMPSAAACQVSMSLGLRGPVFGVTSACSSANHAIASAVDQIKCGRADVMLAGGSDAPLVWIVLKAWEAMRALAPDTCRPFSAGRKGVVLGEGAGMAVLESYEHATARGATILAEVAGVGLSADAFHITAPAVHGPESAMRACLADAGLNAEDVDYLNAHGTGTKANDQNETTAIKRVFGDHAYSMSISSTKSTHAHCIGAASALEMIACVMAIQEGVVPPTANYREPDPDCDLDVTPNVPRERKVRVAMSNAFAMGGTNAVLAFKQV
What is the function of this protein?
Proposed to synthesize NOD factor fatty acyl chain.  Involved in the synthesis of a highly unsaturated fatty acid moiety, which forms part of a lipo-oligosaccharide that is responsible for host specificity.
What are the official names of this protein?
Nodulation protein E, Host-specificity of nodulation protein B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: Y2085_MYCTO
Sequence: MSDMCDVVSFVGAAERVLRARFRPSPESGPPVHARRCGWSLGISAETLRRWAGQAEVDSGVVAGVSASRSGSVKTSELEQTIEILKVATSFFARKCDPRHR
What are the official names of this protein?
Uncharacterized protein MT2147.
Protein: PDXS_SULAC
Sequence: MRLYDLSFYEIEKFFYKLAELKDIISDTGLLSISPSIPQTLPAQGTVMAKHAFPIFQKGGVIMDVTNVTQAEIAENAGAVAVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMAKVRIGHYYEARVLEALGVDMIDESEVLTPADEEHHINKWEFKVPFVNGARNLGEALRRIYEGASMIRTKGEAGTGNVSEAVKHMKIMNYEISTLISLPEEDRLKKAREYQVPYQLVELVVKLKRLPIVNFAAGGIATPADAALMMWLGSDGIFVGSGIFKSQDPDQRAKAVVLAAANWEDPEIVLEAQKMISENKSMMGIDIKTLKPEELLQVRGV
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MAL12_YEAST
Sequence: MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
What are the official names of this protein?
Alpha-glucosidase MAL12, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SYH_PROM3
Sequence: MTQLQSLRGMVDLLPEQTRCWQAVESVARDHFRRAGLQEIRTPLLEVTELFARGIGEATDVVGKEMYTFVDRGDRSCTLRPEGTASVVRAALQHGLLSQGPQRLWYGGPMFRYERPQAGRQRQFYQIGVEYLGVGSPRSDAEVIALAWALLVDLGVQGLVLEINSLGTLQDRQKYREELVAWLEARSDQLDDDSRKRLYTNPLRILDSKNPAISELLQDAPTLFEALSVESKARFEEVQVDLEALQIPFQLNPRLVRGLDYYGHTAFEITSDQLGAQATVCGGGRYDGLVEQLGGAPTPAFGWAFGMERLMLLLESAASINPNGSAARLTASTRPDLYVVNRGEQAERVALVIAHQLRAAGLVVELDSSGSAFNKQFKRAGRSRATWALVIGDDEAERGEARLKYLQEATTQANPIPIDQLHRLDDVTGLVRLVRE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_CAMFF
Sequence: MPNLYLVSLGCNKNLVDSEIMLGRLSSYNIVDKPNNADVMIVNTCGFIESAKEESVRTILELASYKKENSVLVVTGCLMQRYRDELMKELPEVDIFTGVGDYASIDEMILKKQNLFSPGVYLQKSDTKRVITGSSYHAYIKIAEGCNQKCSFCAIPTFKGKLKSRDINSIIKEVKELTKDGYSDFSFIAQDTSSFLRDAGINDGLIKLIDEVEKIEAVKSARILYLYPTTASMGLIDKIIASPKFVNYFDMPIQHINDDMLKIMRRGSSKERLKELLTKMRVAPKSFLRTGIIIGHPGETGERFDELCDFLTEFKFDRISAFAYSKEEGTLAYEMEQIPSKTITKRLNTIEKIIKKQIEGSFKSLVGEVIKVQINGSSSEGEMFFGAKSIIWDREIDGEILINDTQIKDPKVGEIYDCKINEFVKDKLIGEIICNS
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD6_YEAST
Sequence: MEARRYGPNIIVTGTPGCGKSSTCEFLKNKLKDYKYYNISDFAKDNDCFEGYDEGRKSHIVDEDKLLDMLEPLLRQGNSIVDWHVNDVFPERLIDLVVVLRCDNSNLYSRLHARGYHDSKIEENLDAEIMGVVKQDAVESYEPHIVVELQSDTKEDMVSNVSRIVAWEKMWLEQHPDGVTNEYQGPRSDDEDDEDSE
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has also ATPase activity (By similarity).  Involved in 18S rRNA maturation.  Required for cleavage of the 20S pre-rRNA at site D in the cytoplasm.  Involved in oxidative stress response.  Required for POS9-dependent target gene transcription upon oxidative stress.
What are the official names of this protein?
Adenylate kinase isoenzyme 6 homolog FAP7, AK6, Dual activity adenylate kinase/ATPase, AK/ATPase, POS9-activating factor 7.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PTR37_ARATH
Sequence: MASSVTGDAETAISADSSTKRRGGGWITFPFMIATLLGLTIAAWGWLLNLIVYLIEEFNVKSIAAAQIANIVSGCICMVPAVAAIASDSFFGTIPVISVSAFISLMGVALLTLTASLDTLRPRPCETASILCQSPSKTQLGVLYTAITLASIGTGGTRFTLATAGANQYEKTKDQGSFFNWFFFTTYLAGAISATAIVYTEDNISWTLGFGLSVAANFFSFLVFVSGKRFYKHDKPLGSPFTSLLCVIFAALRKRKAVVSTNEKDYHNESITMPTKSFRFFNRAALKQEDEVKPDGTIRNPWRLCSVQQVEDFKAVIRIIPLALATIFLSTPIAMQLSLTVLQGLVMDRRLGPSFKIPAGSLQVITLLSTCLFIIVNDRVLYPFYQKLTGKHLTPLQRVGIGHAFNILSMAVTAIVEAKRLKIVQKGHFLGSSSVADMSVLWLFPPLVIVGIGEAFHFPGNVALCYQEFPESMRSTATSITSVVIGICFYTSTALIDLIQRTTAWLPDDINHGRVDNVYWILVIGGVLNLGYFLVCSWLYRYRNLKDDDHKQAANVSH
What is the function of this protein?
Transporter involved in a passive nitrate efflux.  Not competent for chloride transport.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 2.7, AtNPF2.7, Nitrate excretion transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBUD_RALPI
Sequence: MTKYNEAYCDVLIVGAGPAGVMAAAHLLSYGTTARPHRVRIFDATKEVNGSDESTESLSTDVIADALNSGASGPEKDAASTTEDLPMLVTTLQVSDVLHDTGDDTKIAYRETATEQQVLLLADTTANTSSTMNPRSMCEAGCRFHQIYQGHCFPEYELDSERLRSVDGRAQVLEDEHETGQLRLERLGRPEELLELDEENSMSVVTNLKAAPYKFLMKDVDENFPGELSTSGGKTTSISADESAIDAALHAVWDADDLGAAWHLDEASGLRAVDWNAAQWFKSGQPWTPDAAKSLQEGRVFLAGDARHRHPPLTGIGKNTSIADCYNLTWKLLGVLLGVARADPARTYVAERVYIRMRAATDIAVDAEMESLAAKWITVQLTLSRSWISSAKEAERWDAVLRDSAMSASKPMWTTSDMRASFDAGLMGHGHAHDHVTPTIKEFASSSISRSISELASTSWWESRGWGNGGPFESLMEDARWTGAVESNCRYAAYDRDAPVLHEHVAWVTRFTSRARTAVLEAAVGQAHVVDCWDVGLVEPALDDLDSAGAGLHVAHHADQWPAQLDEAVWPRESLSDWRIVTDTSATGEGYQTSPREAPGDYADLNADNAKAHFNGQFAGHKAYGDAAAADGGGCHGRILVGPAVRGRHLHREIPLGEECQRAAQPLFKEV
What is the function of this protein?
Hydroxylates phenol to catechol.  Also acts on cresols.
What are the official names of this protein?
Phenol 2-monooxygenase, Phenol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_PIPCE
Sequence: MDKTKRPLRKSKRSFRRRLPPPIGSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITIAIKQARILSSLPFLNNEKQFERPESIPKTAGPSIRNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOD2_ROSS1
Sequence: MTVAEIRARNLSIPAPSQITRPALAGEKETMVLNMGPHHPSTHGVLRLVVELDGETVVDVAPDIGFLHTGIEKTMESKTYQKAVVLTDRTDYLAPLSNNLSYVLAVEKLLGCEVPERATVARVLLVELQRIASHLVWLGTHALDLAAMSVFLYGFREREQILDIFELVSGARMMTSYFRVGGLAYDLPAGFDAAVEAFLQIMPGRIDEYEALLTDNPLWIERTQGIGAIDSEAAIALGLTGPGLRATGVAWDLRKTMPYCGYETYSFAIPTATHGDIYDRYLVRMAEMRESVSICRQALQRLRDIGPGPYMTSDRKIAPPPKSEITQSMEALIHHFKLWTEGFKPPRGDALAAVESPRGELATYIVSDGSAKPYRVHFRAPSFVNLQSLPHMARGHLVADLVALIASLDPVLGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHKG1_RAT
Sequence: MTRDEALPDSHSAQNFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPRGKFKVICLTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEEDF
What is the function of this protein?
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase.  In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).
What are the official names of this protein?
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, Phosphorylase kinase subunit gamma-1, Serine/threonine-protein kinase PHKG1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: IF5A_STAMF
Sequence: MSKTYATLGELKPGNFIIIDGEPCRIVEMSKAKTGKHGSAKAHVVAIGLFTGNKKTLVAPVDQRVEVPVIEKRVGQIIADMGDLLQVMDMETFETFEVEKPSDEKLREKLKPGVEVEYWVVMGKRMIIRTR
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIU_SHIFL
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLTDSEDGEISDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: HTPX_ACIBY
Sequence: MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQAMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS1_I67A0
Sequence: MDSNTVSSFQVDCFLWHVRKQVVDQELGDAPFLDRLRRDQKSLRGRGSTLGLNIEAATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEELSRDWFMLMPKQKVEGPLCIRIDQAIMDKNIMLKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRHPLTPKQKQ
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: QUEF_SHIB3
Sequence: MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGLKADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQTRFNNWDEVRQTLERDLSTCAQGKISVALYRLDELEGQPIGHFNGTCIDDQDITIDNYEFTTDYLENATCGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPSTTRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_RICFE
Sequence: MINVEIIKNYDKWREHKQINKSLIKKITQNVLLRFDNFSKIKQFELSILLTNTAEILTLNKQFRNIEKATNVLSFPSNELNWQDLYSKLEFLGDSDYIHLGDIAFCYEVIYNESCEQQKNFENHFIHLLIHSILHLIGFDHQNDTEANIMENLEIEILSYFGISSPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FICD_RAT
Sequence: MILMPMASVVAVAEPKWVSVWGRFLWMTLLSMALGSLLALLLPLGAVEEQCLAVLRGFHLLRSKLDRAQHVVTKCTSPSTELSVTSRDAGLLTVKTKASPAGKLEAKAALNQALEMKRQGKRGKAHKLFLHALKMDPGFVDALNELGIFSEEDKDIIQADYLYTRALTISPFHEKALINRDRTLPLVEEIDQRYFSVLDSKVRKVMSIPKGSSALRRVMEETYYHHIYHTVAIEGNTLTLAEIRHILETRYAVPGKSLEEQNEVIGMHAAMKYINSTLVSRIGSVTIDHMLEIHRRVLGYVDPVEAGRFRRTQVLVGHHIPPHPRDVEKQMQEFTQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTEVTLDTLLLATTEYSAALPEAQPNHSGFKETLPVRP
What is the function of this protein?
Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity).  The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity).  Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP (By similarity).  In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it (By similarity).  In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (By similarity).  Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates (By similarity).
What are the official names of this protein?
Protein adenylyltransferase FICD, AMPylator FICD, De-AMPylase FICD, FIC domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the fic family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RS20_SYNJB
Sequence: MPRIKSAIKRVQIAERNRLRNKATKAMVRALMKKVISLSTAYAANPQQETLQEIQAAMSAAFSRIDKAAKTGVLHKNTAARRKARLARIVKLSVASSEKSQAEALVEHG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PYRD_ECOK1
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQVMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYB_TRYBO
Sequence: MFFRLRFLVFFVLFRNLCCLLLSGDLFRVYGLGFNLGVMIALQILVGICLSWFFFRCIIPQNWIFTLLIHLEFDLGFIIRSLHIIFTSLLYFLLYIHIIKVIFLCLIFDSSMLVWFFGFLIFIFILIIAFIGYTLPCTSMSYWGLTVFSNILATIPLIGIYICQWIWCSEFINDFTLLKLHSIHIFLPFVLLFLIGAHFFVLHYFLSSDGLLDRFPFYYERFFFFLLYYLRDLFLIINILCFLIYYICIYWFFVFHEESWIIVDTLKTSDKILPEWFFLSFFGFLKSVPDKFMGLFLLFVLCFALFLFILNCILIFIYCRSSLLWMSLSLVLFYYLCVGGFLSLYVVLCFPLWMEIQFWVLLLFCFIVCRLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARC_CORGL
Sequence: MVTMSSPTDSSPSNSFSDFNREEQSRLSDEVRQLKRTNSDLGARNAKLAEMLKSSRDKLSVLFSQLEDMAQPPSVYGTFLETAKDGSNAEIFAGGRRMRVAVSPMLCAADLMPGVQVRLGEGNQVLEACDFEQTGELATLMEMIGRDRALVSDRSGEERVVKLAGPLMDRTAKLPRPGDTLLVDRKAGYAFEAIAKTEISRLALEEAPDVSYQDIGGLDDQIELIQDAVELPFLHPEMYRAYNLHPPKGVLLYGPPGCGKTLIAKAVANSLANRIGETGTSYFINVKGPELLNKYVGETERQIRVIFERARELAGDGRPVIIFFDEMESIFRTRGSGVSSDMETTVVPQLLAELDGVEDLSNVIVVGATNREELIDPAILRPGRLDIKIRINRPNKQGAHDIFTRYINDSIPLAEPAEDLIDRAVDHLYTPRPYVRLTLIDGSVETLNYHDFVSGAMIANIVDRAKKSAIKAHIDGTGVGLTAEQLIQAIDDENQQSEDLPNTSNPDEWSRITGRQGKQVTHAEVVI
What are the official names of this protein?
AAA ATPase forming ring-shaped complexes, ARC.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: Y599_TREPA
Sequence: MMQLRCACERVFDIEHETVISLDEHPEFVARIQQGDFLSYQCPACGARIRAEIKTEFVWHAKNVHLLLVPERERLRCLAFCAGMHMSDGDSADFCEPFVLREHQTPVIGYAELADRVAILAWDLNPEIVEAVKFFVLEGAPHLGDKRVSCFFERCVGDTGSRVMELHVYGIREQQTAIMPVPMNVYERVERERGKQAELFEALYVGAYLSYKNVFTDA
What are the official names of this protein?
Uncharacterized protein TP_0599.