PharMolix/UniProtQA huggingface dataset:
Protein: LEUD_XANCP
Sequence: MTPFTQHTGLVAPLDRANVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDIGEPGRDNSTRPLNQEFVLNFPRYQGASVLLARENFGCGSSREHAPWALDEYGFRAVIAPSFADIFYNNSFKNGLLPIVLAEAEMDALFEQCLGNEGYQLTVDLAAQRVRRPDGVEYAFEIDAFRKHCLLNGLDDIGLTLQDADAIGRFEQGHRAQQPWLFGALQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CBLC_HUMAN
Sequence: MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.  Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3.  Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR.  Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation.  Promotes ubiquitination of SRC phosphorylated at 'Tyr-419'.  In collaboration with CD2AP may act as regulatory checkpoint for Ret signaling by modulating the rate of RET degradation after ligand activation; CD2AP converts it from an inhibitor to a promoter of RET degradation; the function limits the potency of GDNF on neuronal survival.
What are the official names of this protein?
E3 ubiquitin-protein ligase CBL-C, RING finger protein 57, RING-type E3 ubiquitin transferase CBL-C, SH3-binding protein CBL-3, SH3-binding protein CBL-C, Signal transduction protein CBL-C.
Protein: NUON_CHLCH
Sequence: MFELPSGAEIQSIIATLKASVGFFIPEIYLSLLFMILIVVDLVVKGRKSTLLSVFSLVGLAGSLYFIYQQHAMQAGEFFFGMYVLDGFAIFFKYFFVLSGMLAVVITMADEQFEREISSMGEYYALVVAMVVGMMMMASSSDLLMIFLSMELVSFTAFILAGYFKSNMRSSEAALKYLIYGAVSSGLMIYGFSLIYGVTAQTNLIAISRELALHGADSFVMLFAALLVLAGFGYKIGAVPFHFWAPDVYEGSPTPVTAYLSVASKAAGFALLMRFVYVALPHTNNVQAATLGIDWFTLLVILAVASMIYGNVVALWQKNVKRLLAYSSIAHAGYALLGVIVMDKLGTQATLFYLLSYLLMNFGAFFVVVLIANRTGSESLDDYRGLGKSMPLAGAALTVFLISLVGLPPTIGFIGKLMVFSALIAKGSIFMWLALIGILTSVISLYYYMLIPLNMYLREPVQHASSNTGTQPRLVAQLFMGALMLLTIYFGLFFAPLSDFARYSASIFGLQLQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OTC_ECOLC
Sequence: MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_CORK4
Sequence: MILSDRDIRSAIDSGHLGISPFDPTMVQPSSIDVRLDRYFRVFNNARYTHIDPKQEQEDLTSLVEVKEGDAFILHPGEFVLGSTLEEFALPADLAGRLEGKSSLGRLGLLTHSTAGFIDPGFNGYITFELSNASNLPIALYPEMKVGQLALFMMSSPAETPYGSGSLGSKYQGQRGPTASKAYMNFR
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CHAC2_RAT
Sequence: MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPGGSVWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDSTTKPFSVLLYIGTCDNPNYLGPAPLEDIAEQIFNAAGPSGRNTEYLFELADSIRKLVPEDADEHLFSLEKLVKERLEGK
What is the function of this protein?
Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide.  Acts specifically on glutathione, but not on other gamma-glutamyl peptides.
What are the official names of this protein?
Putative glutathione-specific gamma-glutamylcyclotransferase 2, Gamma-GCG 2, Cation transport regulator-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SECA_DESAP
Sequence: MLGFLKNFLDDNAREVKKLQRVVTAVNELEPRIEKLTDAELQAKTPALRERLEAGAPLDDLLPEAFAVVREVSRRVLDMRHFDVQIMGGVVLHQGKIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLAKRDSEWMGHIYRFLGLSTGLIVHGLDARQRQASYAADVIYGTNNEFGFDYLRDNMAMYPRDLVQRDLYYAIVDEVDSILIDEARTPLIISGQSGKPTDTYYTMARLVPKLKAETHFAVDEKARTVSLTEEGFARCEELLNIDNLSDPEHEEVLHHLNQALKAHALMKRDRDYVVKDGQVIIVDEFTGRLMFGRRYSDGLHQAIEAKEGVKIERESQTLATITFQNYFRMYEKLAGMTGTADTEAEEFKKIYGLDVVVVPTHKPMIREDLPDAVFKTEEGKFRAVVEEIAARHATGQPVLVGTISIEKSEVLSRMLTRRGIPHQVLNAKYHEKEAEIVAQAGRIGAVTIATNMAGRGTDIMLGGNPSFLALQEMRRRDYPPEVIAEAAEYGPCTEEVAEARRVYRELYAEFKKETDAEHDRVVALGGLFIIGTERHEARRIDNQLRGRCGRQGDPGATQFFVALNDDLLRLFGGDNIAGLMDRLKMDEDAPLEHPLISKSLETAQRRVENRNFSIRKHVLNYDDVINQQRELIYRQRRQVLCGEDLRPVVRQMMEEVAGQAVTAFAPEGVYPEEWNYEGLSEYMTQILPGEKWTVEDLEERLGKKRDDFRREDLRRLFLNEMEQAYAAREAELGAETMREIERVLMLRIVDEKWMDHLDAMDQLREGVGLRAYGQKDPLVEYKFESFDMFQNMIASIQEETVKKLFRVRVVPPQQAERRQVKENLYAAGGDGVKQPVRRDKKVGRNSPCPCGSGKKYKKCCAAKDEQAAG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: FTSZ_MAGGM
Sequence: MLNFLPGNPQDLKPKITVIGVGGAGGNAVNNMIASRLEGVEFIVANTDAQAINQSRTERRVQLGTTVAQGLGAGSRPEIGRAAAEESLEEVIGQIAGANMVFITAGMGGGTGSGAAPVIARAARDHGILTVGVVTKPFHFEGAHRMRTAEGAIEELSQYVDTLIIIPNQNLFRVATERTTFADAFKMADDVLYSGVRGVTDLMIMPGLINLDFADIRTVMSEMGKAMMGTGEAEGDKRAIEAAEAAISNPLLDDTSMKGAKGVLINITGGMDMTLFEVDEAANRIRDEVDPEANIIFGSTFDEKLNGKMRVSVVATGIASEAAAQPKPTVVSLNTPQAQPQPRVAAGGTAGAGFRPAVVTAQAAPAAAVAVAQAQPQMEARTVAQPAPQPAHQPVVTAQVRVQPAAARPAQQPMAETFRPDPQLRLDPVLERPVPATTSLQADFRADPDMGHLSQAVSHIAETAQAAPQPQRQPEIQRQQAPQPQRQPEPEARRSGGLFGLLRRPAAAQPAPQPQRHEPAPMAQQPRQEPARMGNMATRSEPSVARAGEDLDIPAFLRRQAN
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity (By similarity).  Mild overexpression impairs cell division, leading to very elongated cells.  Isolated protein forms filaments and bundles in the presence of GTP (PubMed:24272781).
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane (Probable). Upon mild overexpression during extended growth additional foci appear, which are probably blocked division sites. Foci colocalize with FtsZ-like protein (also called FtsZm) (PubMed:24272781).
Protein: SUCC_YERPG
Sequence: MNLHEYQAKQLFARYGMPAPTGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKLVNSKEDIRAFAEQWLGKKLVTYQTDANGQPVHQILVEAATDIDKELYLGAVIDRSSRRVVFMASTEGGVEIEKVAEETPELIHKIALDPLTGPQPYQGRELAFKLGLTGKQVGQFTKIFMGLATLFLERDLAMVEINPLVVTKQGDLICLDGKLGADGNALFRQPELREMRDPSQEDAREAHAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVFVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAATSLTDAAQQVVAAVGAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MED7_ASPOR
Sequence: MADAGQQRPLTAFAPPPPLWKHFTPDNLKKLDEIKKNASKGEDGKPQKKKWTPTELRALDVPPELHFLVPPEIPKSGHYSVFGELQSLSTALPSLQDQGITQLYPSPPTGDADREQPSEPSQPLNHAYYLLKISKSLLLNFLEFVGILSVAPEQFESKVEDLRNLFINAHHLLNLYRPHQARESLILMMEEQLSRTREEIQQMDKLKEEITGALEQLKKDGVDVDAAPIEAPDNDTKKPNVSEEKAIEDTRLVWELLDENN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YH009_HUMAN
Sequence: MLSARNSMMFGHLSPVRIPRLRGKFNLQLPSLDEQVIPARLLKMEVRAEEPKEATEVKDQVETQGQEDNKMGPCSNGEAASTSRPLETQGNLTSSWYNPRPLEGNVHLKSLTEKNQTDKAQVHAVSFYSKGHGVASSHSPAGGILPFGKPDPLPTVLPAPVPGCSLWPEKAALKVLGKDHLPSSPGLLMVGEDMQPKDPAVLGSSRSSPPRAAGHRSRKRKLSGPPLQLQLTPPLQLRWDRDGGPPPAKLPCLSPEALLVGQASQREGRLQQGNMRKNMRVLSRTSKFRRRKQLLRRRKKTRQGRRGGSCL
What are the official names of this protein?
Putative UPF0607 protein ENSP00000382826.
What is the protein family that this protein belongs to?
Belongs to the UPF0607 family.
Protein: RSMG_RHILO
Sequence: MSSFSLESLQDAAGPVSRETFDRLVAFEAMFQKWNRSINLVAQSTAGDVWQRHILDSAQLARIEPNATHWVDIGSGGGFPGLVMAFLLAERAGASIDLVECNRKKASFLQTVIGQFNLPARVVARRIKDSHALVPQPQIVTARALASLSVLLELTAPWLTSGARGLFHKGRDYRAEVQESVNRWAFDLVEHPSVTDPHGVILELSNLRPV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_DESVH
Sequence: MEYKVEDVSPVKKKVNVTVPVEEVDAALGAAIAMYRTSVNLDGFRKGKVPASIVENRFRKEIYAEATQDLVNVHINEIVTSLAVSPLSRIDFDGGELERGKEFSYTISFEVMPQFDLPDYEGFAVEQEKAVVDEKEVDEVIARIRRNMAELVPVAETRPGADGDVVVLDFAAFENGEPIEGVSAENFQLSLGEKQSLEDFENLVKTIPAGQEAEGPITFPDDFLNPDFAGKTVTMKVKVHAVKERRLPEIDDALAQKAGGFESMEKMRETVVTSYMQSREQLHKATAQKSMLDKLLKMVDFALPESMVDMYVGNLIEDMRVKMERQGRGLESLGKTPEQLREQVLPEAQQIARSQIFLLAAGRKEAVEVSEQEVDGQLQQLAMRSGQDFDTLKDYYVRNGLIFNLRDRLIADKAMDAIYAKANVTMVDPAPAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL2_LARHH
Sequence: MALVKVKPTSAGRRAVVKVVNKDLHKGAPYAPLLEKQIQNAGRNNNGHITTRHKGGGHKHHYRVVDFRRNKDGIVAKVERIEYDPNRTAHIALLCYADGERRYIIAPRGLKAGAEVVNGAEAPIKAGNCLPIRNIPVGTTIHCIEMQPGKGAQLARSAGASVMLLAREGSYAQLRLRSGEIRKVHIDCRATVGEVGNEEHSLRKLGKAGATRWRGIRPTVRGVAMNPVDHPHGGGEGRTGEGRVPVSPWGTPAKGYRTRNNKRTDNMIVRRRHSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RNPH_BRUAB
Sequence: MRPSKRAADEMRAISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNTGKGWVTAEYGMLPRSTGERMRREAAAGKQGGRTQEIQRLIGRSLRAVVDMQALGEMQITVDCDVIQADGGTRTAAITGGWVALHECLRWMEARQMVRVEKVLKDHVAAISCGIYEGVPVLDLDYAEDSVAETDSNFVMTGKGGIVEIQGTAEGVPFSEEEFGALMKLARSGIDRLVSLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PROB_BURMA
Sequence: MRSIIADSKRLVVKVGSSLVTNDGRGLDHDAIGRWAAQIAALRGAGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDTLVILTDQPGLFTADPRKDPGATLVAEASAGAPELEAMAGGAGSSIGRGGMLTKILAAKRAAHSGANTVIASGRERDVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVDDTGREVARGITNYSSAETKLIQRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAO8_SCHPO
Sequence: MSDIDKESLKQNQKQWENEVELGESREANQDDELLMSLGYKPEFTREFSYVSIFGQSFGSMGLCPAMAGSLIFSMNCGGGGMVWSWIIGCICLIPVSISLGELASSMPTSGGLYFWIFTLASPSSRAFLCWVCGYVSVLGYATIYASTVYSASSMVQALAVIGSPSYSPTKYEQYGIYAALLFVISAMTAIPSRVIAKVNIINITFQFLVSIILIIALAAGSDSTTRNSGSFIFGDFTNYSGWSNMGWAFILSFTTPVWVVSGFESSAAVAEESTNAAKAAPFAMISSLGVATILGWCIVITVVATMGHDFNAILGSSLGQPVAQVLVNNVGNKGALGIFSLLVIALCLNCISLLIAASREVFAFCRDGGIPGSRYLRLLTKQKVPLNAILLVLLYSLLVGLLILVNVTAISSVFNLAIIALYIAYSGPLMCRFVYNKFQPGVFYVGKWSKPAALWSLVWMWFMILMLLFPQYQKPNQDEMNWAIVVLGFVMVFCVVYYYLPKIGGKTFFTGPIPTVQQENEYISGVPLNELSLSSLPLPKDFDQKQITE
What are the official names of this protein?
Uncharacterized amino-acid permease C11D3.08c.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRC_LACH4
Sequence: MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRMAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQAALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKDYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: EFTS_BURMA
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMAKAEELLRVKLGNKASKAASRVTAEGVVASFVGANAGALVELNCETDFVAKNDDFNAFAKTVAELVATQNPADVAALSALPLDGKTVDEVRLALVGKIGENISIRRFVRFETSNKLATYLHGSRIGVIVEYTGAQEQVGKDVAMHVAAMKPVSLSADEVPADLIEKERRVAEQKAAESGKPAEIVAKMVDGSVQKFLKEVSLLNQPFVKNDKQTIEQMLKAADAAVQKFALFVVGEGIEKRQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_WOLPM
Sequence: MGNVNPKGFRLKIINTWSSIWYAEKGYKQGLHQDLSIRSYINESFKHAGVSKVIIERTIDLVSVIIHSSRPGVIIGKKGSDIEKIKQKIAEKVKNNVEVNVVGVKRSEIDAVLISNSIAQQLEKRVSFRRAMKKAIQSCLRMGARGIKVSCSGRLGGAEIARTEWYKEGRLPLHTLRANIDYAFAEAKTIYGIIGVKVWVYIGN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RPOC_BORHD
Sequence: MKEIKDFEKIRIKIASRDQIRSWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSIRYKGIICDRCNVEVTHFKVRRERMGHIELSAPVAHIWYYKYIPSRIGLLLDITASNLNSILYYEKYIVIEPGDTDLKKMQLLNEDEYSEAKERYGMSFSASMGAEAIKTLLENLDLDELSSKLRLQMIDKDDKTDKKLLRRLEIIENFKVSGNKPEWMIMDVLPVIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGTSNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGIPAKMALELFKPFVIRKLIESESVFNIKRAKSLIEQEVDEVWQILDNVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLLNPANGHPIVFPSQDIVLGLYYLTMERKNVVGEGRKFANFNHVLLAINNKSLDYNAQIYVKIDGEYIATTAGRVVFNEALPGKITFVNKTLSDYELQSLISEVYVIYGSSIVIEMLDIIKELGFRYATKFGCTISMSDIIVPEEKKIYVDKANREIAKIQNDYTKGVITGEERYNNVVSVWSKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIELPIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVEALKNGEEIVEPLREKAVGSYSIERIKSPITGEIILDVNEEVTEDKIKLLETVGIDKLVIRSVLTCEAEHGVCQKCYGRDFSNNKPVNIGEAVGIIAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKIALKNAFILNGLEGFNVQVDDGLLFTRKGTLKVINVIYEENIKEIKELKVLDSQKVIKGMPLFINKNGIDVLSTHIGYVKIKDDKLMIVSEEQEISLKAGTRLEINVGDYVEAGRVIGTFDPFAEPIIAEFKGKVKFKDIILGTTLKEEINLETGNIEKRITDQVFESLDPRILIINDRGVEITSYVLPGDAYLQVEDGQDINIGDVIAKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGIVQFKAIQKGKRLINVLDEYGVEHKHYIPAGKHLLVRDGDVVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVSVGDTNFVYNQKVDKHAFYEQNKRVIEQGGEPAVASPILIGITKASLNIDSFISAASFQETTKVLTDASIAGSVDDLKGLKENVVIGHLIPTGTGMNLYKRVKVRENSSSEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UTP25_PHANO
Sequence: MQHAPEPGESQSEDSDDSVSDNDDDEEDAQPTSNAYAALLQSLSTVAKQNEHQETHRRKKRKLAGEDLQVAEEPQQKINRNMSNLTEDEPDAVFDGDALDEDPQEDAASDDGVQIRDAVEETQDGFESFEVHFANPDENDLAMRLRRISENQWSAKKLHAAGGRALLQVPCADNTAFDTRKLRSTRDVQLKARLAENAQKVVGQFNDGHEQVIMPSIFGYQDVLFAARTVHNAARMRDITCLHALNHILIGRDRVLKNNAKLAAANDGDDVEYRDQGFTRPKVLFLLETKQACVRVVDSITRLFTFEQQENKKRFLDQFHRPDQAFSDDKPADFRELFEGNDENEFRVGVKLTRKTLKFYSTFYNSDIIFASPLGLRRAIETGDPKKRSGDYDFLSSIEMVIMEQADANLMQNWEHAEFVFEHLNLQPKESHGCDFSRVRPWYLDDNAKHVRQTIVMSAFLTPKINTLWNKHMRNFFGRLKYTPDYSAGVIESLSHGIKGIKQTFWRFESPSHLTDPDARFKYFSSTILPSILRTPKPAEGGPGILMFVPSYLDFTRLRNSLVDVNISYALISEYTDMTDVRKARSHFMNGKHSLLLYSGRAHHFHRFNIRGVKRVVFYGVPENPIFYEELVSMVGKSVERGETSRAEASIRVMFSKWERMELERIVGTKRLSRMVGDKGDVFDFVY
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SMDC1_BOVIN
Sequence: MEQRLAEFRAARKRAGLVAEPSASSQSTQTSGEKAEAATTPKAPSGWLKRFLVWKPRPPSAQAQPSLAQGAAWPRGLESQPPWSPAEEAPPPPQPPPPQPLTPRDRSLLTSVTLLKVLLWLVLLGLFVELEFGLAYFVLSLFYWMYVGMRGPEEKMQGEKSAYSVFNPGCEAIQGSLTAEQLERELHLRPLPRR
What are the official names of this protein?
SAYSvFN domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass membrane protein.
Protein: RRAAH_DEIRA
Sequence: MTDFIPTTDLSDAQPQAQVAAPVLRDFGGRTRFQGAAVTLRISENNPLVRQTLQTPGAGRVLVVDGGGSLNCALLGGNLGVFGVENGWEGVIIHGCVRDTAELRELDLGIRALAAHPRRSGKLEEGERDVPVTFAGVTIRPGDHVVADEDGWLVLGAESP
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.