PharMolix/UniProtQA huggingface dataset:
Protein: CMOA_METCA
Sequence: MSRDEIYRQSQSFLDDFGFGESVATVFDDMLERSVPFYAELQRMIAEMAGDFAMPHTRIYDFGCSTGTTLIGLDQAIGPRGLTLVGVDNSQEMLAKCRAKMAGHAFANAVELIRADLNQGVVMENASLALMILTLQFVRPLYRDRLVRAIHDGLEENGALVLVEKVLGESSLFNRSFIKYYYEFKKRNGYTELEIAQKREALENVLVPYKLAENLEMLESAGFRYVDVFFKWYNFVGIVAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: VIF_HV2D2
Sequence: MEEEKDWIVVPTWRIPGRLERWHSLIKYLKYRTGELQQVSYVPHHKVGWAWWTCSRIIFPLNKGAWLEVQGYWNLTPERGFLSSYAVRLTWYERNFYTDVTPDVADQLLHGSYFSCFSANEVRRAIRGEKILSYCNYPSAHEGQVPSLQFLALRVVQEGKNGSQGESATRKQRRRNSRRSIRLARKNNNRAQQGSGQPFAPRTYFPGLAEVLGILA
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: PNP_PELUB
Sequence: MFKVYKKEIEVAGKKISLETGKVARQADGAIIASCGETVILATVVGAKKVNPDMDYFPLSVNYQEKYYAGGKIPGGYFKREARPTESEQLISRLIDRPIRPLFPSEFKNEVQLLPTVISYDKDNQPDILAITASSAALAISGMPFMGPVGASRVGLVDGKYILNPSKAELENSTLDLVVAGTKDAVLMVESETSGLTEEVMLDAVKFGHEGFVPVIEMIEELAKECRKPEWTVEKKDLSEVKKKLEENFTEDLTKAFATIDKQDRSNQISEISDKAKQLFADDENYSDFNVNDELKNLEKKIVRTDILKNKKRIDGRGLADVRAIECEVGVLPRTHGSALFTRGETQAIVVTTLGTSDDEQRLESLDGQHRERFMLHYNFPPFSVGETGRIGTGRREVGHGKLAWRAINSSLPPKEEFPYTFRIVSEITESNGSSSMASVCGASLALMDAGVPIKEPVAGIAMGLIKEGDDFSVLSDILGDEDHLGDMDFKVAGTKDGITSLQMDIKITGITFEIMEQALKQAKEGRIHILGEMNKALSESRADVGEHTPKMEQITVDKKDIAAVIGKGGATIREIVEKSGAKLDVNDEGVVTVAAPDEESRNIAMQMIKDITAKAELNKIYSGKVMKIMEFGAFVNFLGKQDGLVHISELATKRVEKVTDIVKEGDEVKVKVIGFDRGKVKLSMKQAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRC2_CAEEL
Sequence: MGACSSCLRLLLDAESDVKIHVIEPTSINNGEGSSVVHRDATAPPTPPVVPTSTLQVPGLQRARTPEPNDPRVANL
What are the official names of this protein?
Uncharacterized protein K01A12.2.
Protein: RS12_LACGA
Sequence: MPTINQLVRKGRHSKTTKSDSPALNYAYNSMKKKMNYNPAPQMRGVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGALDTAGVDGRKQGRSKYGAKKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS4_MYCGA
Sequence: MSRYTGSIYRKARRLNFSILESGKEFTNNKSKKGVKVPGQHGSLIRPKLSNYGEQLQEKQKMQFMYGLNDRQFRRLFAVSKKMSGILTMNLFRTLESRLDNLVFRMGFAPTRRGARQLVSHGHVLVNGKTFDIPSALISLGSVVELKPRAHNLPLVKLALESKAVAPFVEVNKKTLSGTYVRYPERNELPADVNETYVVEYYKRLVK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PUR9_CHICK
Sequence: MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPEAVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASKDKDTSVETRRHLALKAFTHTAQYDAAISDYFRKEYSKGVSQLPLRYGMNPHQSPAQLYTTRPKLPLTVVNGSPGFINLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCMVHDLHKTLTPLASAYARSRGADRMSSFGDFIALSDICDVPTAKIISREVSDGVVAPGYEEEALKILSKKKNGGYCVLQMDPNYEPDDNEIRTLYGLQLMQKRNNAVIDRSLFKNIVTKNKTLPESAVRDLIVASIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEVSNAIDQYVTGTIGEDEDLVKWQAMFEEVPAQLTEAEKKQWIAKLTAVSLSSDAFFPFRDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH
What is the function of this protein?
Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis (PubMed:12501179).  Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR) (PubMed:12501179).  Can use both 10-formyldihydrofolate and 10-formyltetrahydrofolate as the formyl donor in this reaction.  Also catalyzes the cyclization of FAICAR to IMP.  Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (By similarity).
What are the official names of this protein?
Bifunctional purine biosynthesis protein ATIC, AICAR transformylase/inosine monophosphate cyclohydrolase, ATIC.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ACCA_CAMJR
Sequence: MASYLDFEKNIQQIDEDIINAQIKGDTEAVSILKKNLEKEISKTYKNLSDFQRLQLARHPDRPYALDYIELILNDAHEIHGDRAFRDDPAIVCFMGYLGEKKIIVIGEQKGRGTKDKIARNFGMPHPEGYRKALRVARLAEKFQIPILFLIDTPGAYPGIGAEERGQSEAIARNLYELSDLKIPTIAIVIGEGGSGGALAIGVADKLVMMKNSVFSVISPEGCAAILWNDPAKSEAATKAMKVTADDLKSQGLIDDVIDEPTNGAHRNKEAAAVAIADYVKKSLNELENIDVRELSANRMQKILKLGAYQEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM2_CLOBL
Sequence: MEIRQNVKFKKPLIHYITNPISINDCANMILAAGAKPIMAEHPLEVSEITSASKSLGVNIGNITDNKMKSMLISGKTAYENKIPQVIDLVGVGCSKLRLDYAKKFISECHPNVIKGNMSEIKAIYGIKSSAKGIDVGACDIITEQNFDENIEMIKRLSMETGSVVAATGVVDIISNGTYTYIISNGCEMLSMITGTGCMLTGIIASYISSGNILEGTALAIVLMGICGELSQHVKGTGSFRNELIDNIFSISDDIIIKKIRINSY
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 2, 4-methyl-5-beta-hydroxyethylthiazole kinase 2, TH kinase 2, Thz kinase 2.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: LUXS_STRP1
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: HXB7_GORGO
Sequence: MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRQGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTAGPGTTAQDRAEAEEEEEE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B7.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CASA1_BOVIN
Sequence: MKLLILTCLVAVALARPKHPIKHQGLPQEVLNENLLRFFVAPFPEVFGKEKVNELSKDIGSESTEDQAMEDIKQMEAESISSSEEIVPNSVEQKHIQKEDVPSERYLGYLEQLLRLKKYKVPQLEIVPNSAEERLHSMKEGIHAQQKEPMIGVNQELAYFYPELFRQFYQLDAYPSGAWYYVPLGTQYTDAPSFSDIPNPIGSENSEKTTMPLW
What is the function of this protein?
Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.
What are the official names of this protein?
Alpha-S1-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTRA_METEZ
Sequence: MAEKKEPAEGWPILKGEYEVGDPNNCVAVITCGSHLEGQPMLDAGASIVGPCKTENLGLEKVVSHIISNPNIRYLIVTGAEVKGHITGEAMMMLHKNGVKDNRIVGATGAIPYVENLTEESVERLQQQLEECVDLLGTEDLNTITSKIKELAEKDPGAFDAEPMIIQLEEEEEEEEEGGIKPMSAEIATIQARIRNIEKDMINAGEMNKLHSGVLAGKIEGIMVGLVLSLFVLGLLLFGGM
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ATG7_YEAS7
Sequence: MSSERVLNYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRSFEKQNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASSDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLSVMKQEVEQLGNDVFEWEDDESDEIA
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7, Cytoplasm to vacuole targeting protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: SYL_NEIMB
Sequence: MQEQYRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPLAAAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFATKYNLPKKQVIAVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLPENVVPDGMGSPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAAKYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGLSKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVLETAVRLLWPIVPHICETLWSELNGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALATEGAVKFMEGKPAKKIIVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_BIGNA
Sequence: MDGTAFFFTIFVWFLLISVTGYSIYVGFGPTSSALRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL30_MYCSJ
Sequence: MAELKITQVRGTIGARWNQRESLRTLGLRKIRQSVVREDNAQTRGLIKTVHHLVVVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SHPK_MOUSE
Sequence: MASRPVTLGIDLGTTSVKAALLEAAPSLPSGFVVLASCARAARAETESAVAGPQGREQDVTRIIQALNECLDALPRQQLQRVRGIGVSGQMHGILFWKAGQGCEWMEGGPAFVFEPRAVSHLVTWQDGRCNSSFLASLPKPDSHLSVATGFGCATIFWLLKNSPEFLKSYDAAGTIQDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNLDTLEKAGFPIHLLPDIAEPGSMAGRTSHTWFEIPKGTQVGIALGDLQASVYSCMGQRTDAVLNISTSVQLAASMPVGFQPLQTPDPAAPVAFFPYFDRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAAQQKDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPFQQLKEWGVARVVGSGSALSRNEVLKQEVQRAFPFPVCFGQDVDAAFGAALVMLQRDLSQKEP
What is the function of this protein?
Acts as a modulator of macrophage activation through control of glucose metabolism.
What are the official names of this protein?
Sedoheptulokinase, SHK, Carbohydrate kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_NATPD
Sequence: MPIEDRDDAHVITHALAKHTLSELRSDETDQVAFRNGLVELGRLCGYEIIDGMMDTEYVSITTPLAETTGEVVKGLDDVVIVNVLRAATPFVEGLVEAFPHARQGVISAGRDEAAGMNEDGEFPITVDYVKLPDIDADDTVIVADPILATGSTMVAVLEEVLEQGTPERLVVLSAVSAPPGLARVNDSIPSADVLTVSVDERLDEDGYIVPGVGDAGDRAFGT
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS16_CALBD
Sequence: MAVRIRLKRMGAKNNPFYRIVVADSRTPRDGKTIDEIGYYNPLKNPADIKVDVEKAKKWLSYGAQPTDTVKILLKKAGVIE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GSIA_SHIDS
Sequence: MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRDVIELSEQSATQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFSLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKDAVARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAAVPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CINAL_ANASK
Sequence: MQVEILATGDELLTGQVVDTNSPWLMDRLWDLGLMVRRKTLVADDRDDLRASILETTARADLVVMSGGMGPTEDDLTSECVAAVLGVPLERHEPSIEVLRERFRKFGRALTPNNEKQAWFPRGAEVIPNRWGSAPGFTVPVGRGRVVCLPGVPVEYRGLCEEWVLPHVGARLGEVPAAGLVKLFAVPESHADHAMRPVMDDPANAGVRFGYRAHWPETHVKWTVPGPGAAARAARIRERVLGIFGEQVFGEGKDELPELVVARLAARGERVALGESCTGGMVAELLTAVPGASAVLDLGVVAYANAAKERVLGVPAELLAAHGAVSEPVARALAEGARRTGGAAWGVGITGIAGPSGGTPEKPVGTVHLAVAGPSGTEAVARAYRGDRDRVRRQAAYEALNLLRLALR
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: FTSH2_SALRM
Sequence: MADQTSQNDNQNGSGLPGGGPSGTGRGRLIIWVIAGTLLALWAYSYWGMGASGGERISYSEFRTQLQQENVERVEVKGNAINGSLKSQATRSEQGNTIEYQNFVTYLPSFGDEQLMDLLESQGVNVVTKPESSFPWGLVIMGLLPVLLLFGVGYIFLRRMQSQGQGLFSVRQSKAELYDKDEEDTTFDDVAGADSAKEELREIIKFLKNPKRFEGLGGKVPKGVLLVGPPGTGKTLLARAVAGEANAPFFSVSGSDFMEMFVGVGASRVRDMFSEAKETSPAIIFIDELDSIGRKRGAGLGGGNDEREQTLNQLLSELDGFEENEGVIVMAATNRPDILDSALTRPGRFDRQITVDLPTKQSRHEILKIHAREKPLSDDVDLEEIARSTPGFSGADLENLLNEAALLAGRHGHDAIQYSDIEQARDKVMMGLKRDGMVLDDEEKKLLAYHEAGHAIVGAVLPNADPVHKVTIVPRGKAMGVTQQLPEKDQYLYRHDYILDRLAVIMGGRAAEELIFDTATSGAENDLKQVRKMARKMVLDWGMGDQFKHISLGEDQGNVFLGDEIAKGREYSDDTAREVDEEIRRISEDAFQRAVDTLNEHHEAFDQLADMLIEQEEVSGKDVLNLVNGDTDEIGHMPTTNGAAASEENGSADDHEPDEATVIEEDGESGEGRASGSADASGS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: AMPD1_CHICK
Sequence: MNQKHLLRFIKKSYRVDADRVVYDAK
What is the function of this protein?
AMP deaminase plays a critical role in energy metabolism.
What are the official names of this protein?
AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: NADD_LACPL
Sequence: MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDAQPPHVDEKKTIAVEDRANMVQEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQYYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTSQYPVIWVDAPLIDISSTQIRQKISHGHSVRYLVPEAVAAYIKEHHLYEQND
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RNPH_ANOFW
Sequence: MRVDGRTNDELRPVHIEPNYLKHPEGSVLISIGDTKVICTASIEDKVPPFMRGGGKGWITAEYAMIPRATEQRNIREASKGKLSGRTMEIQRLIGRALRSVVDLQKLGEKTIWIDCDVIQADGGTRTASITGAFVAMTLALGKMVEEKKLPALPITDFLAATSVGIDGEHGIILDLNYIEDSKAQVDMNIVMTGSGRFVEIQGTGEEATFSYEQLLDLLTVAEKGIHELIARQKEALGSLAEQIMQHCSEGEEAK
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SYN_STRT1
Sequence: MSKQLVSIIDVPKHIGEEITIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFIEKFGEEEGLEKFDTIKHLSQETSIYVTGMVKEDERSKFGYELDINDIEVIGKSQDYPITPKEHGTDFLMDNRHLWLRSRKQMAIQQIRNAIIYATYDFFDKNGFIKFDSPILSSNAAEDSTELFETDYFGTPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHDESLDLQEAYVKALIQGAIDRAPQALEILERDVDLLKKYIAEPFKRVSYDEAIDLLQAHENDEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDDYDALVAKMEELGMDRSEYEFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MABP1_XENLA
Sequence: MATIESGTTITSRLKNLLRSPSIKLRRHKAGTKKEDLSSKVTLEKVLGITVSAGRGLSCDPKTGLVAYPAGCVVVLLNPRKNKQQHILNSSRKTITALAFSPDGKFLVTGESGHMPAVRVWDVAERTQVAELQEHKYGVACVAFSPTSKYIVSVGYQHDMIVNVWSWKKNVVVAANKVSSKVTAVSFSEDSSYFVTAGNRHVKFWYLDEAKSSKVNSTIPLLGRSGLLGELRNNFFTDVACGKSKKSSSTFCITSSGLLCEFNDQRLLDKWVELRTTVANCILVNHDYIFCGCADGTVRIFNPNNLHFLSTMPKPHCLGVDIATVTEASRLFSSAADAKYPDTIAMTFDPTNQWLSCVYNDHSLYVWDVKDLKKVGKVYSSLYHSSCVWSIEIYPEIKDSNQACLPPNSFITCSSDSTIRLWNMETSNIHGTALHRNILSNDLMKIILIDDNTQALLDTEYNSAGLGDKADHQALDTKVGIRSVCVSPNGQHLASGDRTGTLRVHELQSMTELLKVEAHDSEILCLEYSKPDTGLNLLASASRDRLIHVLDASKDYSLQQTLDDHSSSITAVKFAANDGKVQMISCGADKSIYFRTADKVGDAAVHFTRTHHIVRKTTLYDMDVDPSLKYAAIGCQDRNIRIFNISSGKQKKLYKGSQSEDGTLIKVQTDPSGLYIATSCSDKNLSIFDFYSGECVATMFGHSEVVTGMKFTNDCKHLISVSGDSCVFIWRLSSEMTINMRQRLAEVRQRGKQVEMSATHKTQNARRETIAVMSTAPVMSSDSDKEGVEDGSDEDTAGSDKASSASSSFGRSNSYWEMARGTNTSSERSNCLSKMPRQRVRWSQPAGNIEMTVKSMLDLRQLDSFAPCDDIIGFQPSEGLGTEFVVADNSSIQAPFGPIGSRSRPRVIRLMSCEETMFKQDVETPEGKECTIFPEMEEDESLERCGGFEVKGLPLRSYHDNVCQEKHSPDSACSVDYSSRLSSPEHPNEDSESTEPLSVDANSSDLEEQVEAEDLEPNSPVMDGEIPQTPDQEKFLKQHFGNLSAGNIPGGPLLTSERNDFSSISSRFLAMAAPSKNQPVESLMFDSEFSPALFQPSMEHPALINRTESQPKSAITTDHDFTSPQKLNYFQRKRKHLQEYEHIGKGGPFSSVMQIRKTQSVHDLVNEGNKTTANGGIVKMRSQVQTAAEREEKAIRRRTLPSTLIKVENLASGTPHSKDGKLAKGRSYMNPTTSSMAKISRSMSVGENLNIEENQDASLSFDGKGNCEPEIGAIPSFVETEKNRQTAKETVIIKPHLQPVANCSSTKTFQTKNRAHLTLDIAKPLPDRPLLSFNKGKGALEMESPRSPASSCKVKSSFSEFTCRNDNQASGALEKTSPSEDYGCSKSKENDVKANSKPNVYQERVELFSDMLKPIHRGRASTIGHTPDHHSGLCPEVEPIRPRSPSLNAAPTHNSASSVSFEQCELIASELQDSLQKALSLYRSVTTADPSANMERCKIAGLLTETFGMVKRELDFLKEGNSSPGTAMTPQDETGSDFTAPNLHEEHGTRRLGDDKTLALLQQYSELLLQAVEKRMDKKL
What is the function of this protein?
Involved in JNK signaling pathway.
What are the official names of this protein?
Mitogen-activated protein kinase-binding protein 1.