PharMolix/UniProtQA huggingface dataset:
Protein: DAH54_RANDH
Sequence: GLLGSIGKVLGGYLAEKLKPK
What is the function of this protein?
Has no antimicrobial activity.  Strongly inhibits the formation of NO by neuronal nitric oxide synthase at micromolar concentrations.
What are the official names of this protein?
Dahlein-5.4.
What are the subcellular locations of this protein?
Secreted.
Protein: SYA_CYTH3
Sequence: MTSAEIRQQFLDFFASKGHQIVPSAPIVNKNDPTLMFTNAGMNQFKDYFLGNETPKYRRIADTQKCLRVSGKHNDLEEVGIDTYHHTMFEMLGNWSFGDYFKEEAIAWSWELLTSVYKLPKDRLYVTIFEGDDKEKLARDTEAYNFWKKWIAEDRILLGNKKDNFWEMGEQGPCGPCSEIHVDLRTDEEVKAVDGKTLVNNDHPQVVEIWNNVFIQFNRKADGSLEELPDKHVDTGMGFERLCMAIQKKKSNYDTDVFTPMIDFVAKAAGIKYGADEKTDIAMRVMADHIRAISFVIADGQLPSNNKAGYVIRRILRRAVRYAYTFLNLKEPFLYKLVAVLADQLAHVFPELKSQQDFVAKVVQEEEISFLRTLDIGLSKLEQIREELKAKKATTIDGKTAFELYDTFGFPLDLIQLIARENGLTVDEAGFDTEMAAQKQRSKKAASVETSDWTIVTEDDEVEFVGYDHLISTSRIIKYRQVKTKGKDQYQLVLDTTPFYAESGGQAGDTGTLVQGDKKIKVLNTVKENNLIIHITEQLPADLKAPVDCKVNVLQRSLTENNHSATHLLHAALKQVLGSHVNQKGSLVNESVLRFDFSHFSKVTEEELKKVELIVNEKIRENISLNERRNVPIEEAKKLGAMALFGEKYGEYVRMITFDDSFSRELCGGTHVSSTGKIGFFKITSESSVAAGVRRIEALTATAAEVFVDEQQTTLAKITELMKNPKDLVKSLEDLLEERIVLQKQLDEYQAEKSKAIAKSLKDTVEKVGDINVIRAKLVLPSVDAMRQVAYDLKQTVDNLLLVLAVNVDGKPNIAVMISDNLVADKGLNASQMIRELSKEIQGGGGGQPFYATAGGKELNGLDKVIAKSKDLIQVHA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_LIGS1
Sequence: MAHISFDSSNLTKFVNDNELGEMQALVTAVDKELREGTGAGNDFRGFLNLPVDYDKDEFDRIKKAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLHHQFFNLLPAEKRNAPQIFFAGNSISGSYVHDLIELIGDRDFSVNVISKSGTTTEPSIAFRVFKEKLIAKYGVEGARERIYATTDRARGALKTEADAEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGADIDKLMQGAADAREEYSDADLTKNEAYQYAALRNILYRKGYTTEILENYEPTLQYFAEWWKQLMGESEGKDGKGIYPSSANFSTDLHSLGQYIQEGMRNLMETVITVGNPTNDTDIPKEEENLDGLGYLEGKSMNYVNSKAFQGVVLAHTDGNVPNMIVNIPDQTEYTLGYMIYFFEIAVAISGYLNGINPFNQPGVEAYKKNMFALLGRPGYEELTKELQDRLNK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP7_ROTBB
Sequence: MYGIEYTTFLIYLISIILLNYILKSITRMMDYIIYKFLLIVTITSIVVNAQNYGINLPITGSMDTSYVNATKDEPFLTSTLCLYYPTEARTEINDNEWTSTLSQLFLTKGWPTGSVYFKEYDDIATFSVDPQLYCDYNIVLMRYNSSLKLDMSELANLILNEWLSNPMDITLYYYQQTDEANKWIAMGQSCTIKVCPLNTQTLGIGCQTTNTGTFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGADILDITSDPTTNPQTERMMRINWKKWWQVFYTIVDYVNQIVQAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: YORL_BACSU
Sequence: MIGCHCHTDRSNIRLLDSTNSVKELLKTAVKMEYKGLAITDHEVLSAHLDAIRTVREMKKKGDMPEDFKLILGNEAYLVDSLEEVRDNYKSGVTKFPHFLMLAMDPKGHEQLRILSSQAWENSFYTGTMERVPTVKKDVEELLSKDPGHIIATTACLGSEVNIHLLKIKAFEETGDSQSIKQHKLKIHEFITWCIEVFGKDKFFIELQPALSEEQIYCNKKLIDIANGYDLQMIVTTDAHYLRPEDRAIHQAFLNAKDGEREVDSFYEACFVQNVDEIHERMDYIDKEVIDQAIKNTMLIGEMIEDYTIEHEPIIPKMELPNFKLRHLFKPAYDQYEYIKKMSESADEQDRYLLKLIEDGFEEKLKTSELTREAFHKILNRINVELGELWEISQKLNQSMSSYYITVREIINIIWDDECGGDSLVGAARGSAAGYLVNYLLDNTQINPMQYDLPHWRHIHKSRPDLPDIDIDTEGSKRQKILKALRERFGDKRVLQIATFGTEGSKSALQTACRGLGIDNDISQYLSGMIPFERGSNWPLKHCFYGDKETGRKPIKEFIREVEQYPNLKETALKIEGLTNKRSSHAAGVIIFNDEYTKSNAMMKTPKGAYITQFNMGDSEAMGSVKFDLLTIEALDKIRVTLDQLIENNEIEWQGSLKETYNKYIHPDVIEYEDDKLWEMAGNGEIMDLFQFSTEVGHQSVVKVKPKNLLEAAVTNSLMRLMSDGEEQPVDTYVKYKNNLNKWYEEMTRYGLSEKEIRVMERHLKDIYGVADTQEVVMQMVMDKDIANFDIKESNYLRKSIAKKKEDVLKEVEELFFKKGKEIGTSDNLLNYVWNVQFKRQFGYSFSLLHTLAYSIIALQELNLNYRYNPLYWNTACLTVNSGGIDTEDTKDNKKTAATNYGKVASAIGNIRQRGIKIDLPDINKADFGFRTDINNNSILFGLKGMNGIGDDVIHHIVLNRPYSDFNDFIERMFKSGIIKKGQVIQLIKGGCFDSFGNRQEIMKAFISLISEPKSKLTLSNLKMLIENNIVPSEFAQEVRFFRFKDYISKKVYKTLKSPKDKLFLLDDVSASFYNQHFSEDSVVDMLNGQLVISEKAFKKEYDNKMSNIKSWITTEEPLKKLNDCLLIKEWEKYADGSLGKWEMDSLSYYYNDHELSGVNFAKYDIADFYKLPAEPVKGKPYQWRGKTLYEYETTRIIGTVLDRDKNKHAITLLTPTGVVTVKQWSGSFSHYNKQISRSIGGGKKEVIEKSWYTRGTLLMFTGFRRGNNFIPKVYKDSIYNHTVCRIDFVDNEGSMSLTTKRAEI
What is the function of this protein?
Probable DNA polymerase.
What are the official names of this protein?
Probable DNA polymerase YorL.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family.
Protein: PSBS2_CHLRE
Sequence: MAMTLSTKAFAQRGVSARKNTVRVYAATTKVNPKLASKTEVERFKQATGLPAPAINGKQFPLKLGFTKTNELFVGRLAMVGFSASLIGEILTGKGALAQFGYETGLNGIEVDGLVIGLIAFNLIAAVLPTSQTFVPEEQDTISERPAGPLQDPRITLLEPKKFFGVQGFGFTKENELFVGRAAQLGFAFSLIGEAVTGKGALAQFDIETGLSLRDTEFGLVVFILFLLFAAINEGSGKFVDEESA
What is the function of this protein?
Required for non-photochemical quenching (NPQ), a mechanism that converts and dissipates the harmful excess absorbed light energy into heat and protect the photosynthetic apparatus from photo-oxidative damage (PubMed:27358399, PubMed:27329221).  Seems involved in the activation of NPQ, possibly by promoting conformational changes required for activation of LHCSR3-dependent quenching in the antenna of photosystem II (PSII) (PubMed:27358399, PubMed:27329221).
What are the official names of this protein?
Photosystem II protein PSBS2, Protein PHOTOSYSTEM II SUBUNIT S2.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FLOT1_PIG
Sequence: MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAAAEKSQLIMQAEAEAESVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSAKKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQVNHKPLRTA
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endosome. Membrane, caveola; Peripheral membrane protein. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Membrane-associated protein of caveola.
Protein: FB116_ARATH
Sequence: MNSSSPISIDLIAEILSRVPSKSVARFRCVSKPWASMIRRPYFTELFLTRSSPKPCILFATVADGVWSFFSLPQYPYEKSSSASVAASAKFHVKFPPNNMRIGHNSDRRYFSYGYTSGLIYLYGDSSDDRSVICNPYTGEYAILPYLQRYRKTYSFLVFEPIEKQFKILFMAYLSGDRDHKILTVGTGNMKWRTIRCSLRYEIVSEGVSINGVLYYLGETSAWDNKDYDLKYDYAIVCFDIRSEKFIFFEIERFCRLINYKGKLAVIYFEDDVNYQSCLYRKKNYVEPDAINKLNVWVLEDVEKQEW
What are the official names of this protein?
F-box protein At2g23160.
Protein: NUON_SALEP
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUKF_ECOSM
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MURB_CAUVN
Sequence: MTWKTQLPTARGKLLIDEALAPFTWFRVGGPADVVFLPADEQDLSDFLKGLDPSVPVMAIGVGSNLLVRDGGVDGVVIRLGKGFNGVEALGDNRIKAGSAVPDAILARKAAEAGIAGLEFYVGVPGTIGGAVIMNAGCYGAETVNVVKSVRVMNRAGVVRELSVEDLHYTYRHSALQDGEPVIVLDAIFEGTPDEPEAIKARMAEITARRETTQPIREKTGGSTFKNPPGHSSWKLVDEAGWRGKPYGGAMFSPLHSNFLINTGEATAADLEGLGEAVRADVLAKTGVQLDWEIKRIGRAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX8_ANDMA
Sequence: MNYLVMISLALLFMTGVESLKDGYIVNDINCTYFCGRNAYCNELCIKLKGESGYCQWASPYGNSCYCYKLPDHVRTKGPGRCNDR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (PubMed:12911331).  The toxin principally slows the inactivation process of TTX-sensitive sodium channels (PubMed:23685008).  It discriminates neuronal versus muscular sodium channel, as it is more potent on rat brain Nav1. 2/SCN2A (EC(50)=29 nM) than on rat skeletal muscle Nav1. 4/SCN4A (EC(50)=416 nM) (PubMed:12911331).  It also shows a weak activity on Nav1. 7/SCN9A (EC(50)=1. 76 uM) (PubMed:23685008).  In vivo, the toxin produces pain hypersensibility to mechanical and thermal stimuli. (PubMed:23685008).  It also exhibits potent analgesic activity (when injected intraperitoneally), increasing hot plate and tail flick withdrawal latencies in a dose-dependent fashion (PubMed:20619318).  This paradoxical analgesic action, is significantly suppressed by opioid receptor antagonists, suggesting a pain-induced analgesia mechanism that involves an endogenous opioid system (PubMed:20619318).  This led to hypothesis that pain relief induced by peripheral administration of Amm VIII may result from sensitization of primary afferent neurons and subsequent activation of an opioid-dependent noxious inhibitory control (PubMed:20619318).
What are the official names of this protein?
Alpha-toxin Amm8, Alpha-anatoxin Amm VIII, Amm VIII, AmmVIII, Neurotoxin 8, P4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TPM3_HUMAN
Sequence: MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NUOI_ACIBT
Sequence: MYKILAGVGSIVRTLFMVFTHGFRKRDTILYPEVPAEEIVPPRYRGRIILTRDPDGEERCVACNLCAVACPVGCISLQKAEKEDGRWYPEFFRINFSRCIFCGMCEEACPTTAIQLTPDFELGEYVRQDLVYEKENLLISGPGKYPDYNFYRVTGMAINGKEKGQAQKESAPIDVRSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ITAX_MOUSE
Sequence: MSCTWIAFLLLLGFVSCLGFNLDAEKLTHFHMDGAEFGHSVLQYDSSWVVVGAPKEIKATNQIGGLYKCGYHTGNCEPISLQVPPEAVNISLGLSLAAATNPSWLLACGPTVHHTCRENIYLTGLCFLLSSSFKQSQNFPTAQQECPKQDQDIVFLIDGSGSISSTDFEKMLDFVKAVMSQLQRPSTRFSLMQFSDYFRVHFTFNNFISTSSPLSLLGSVRQLRGYTYTASAIKHVITELFTTQSGARQDATKVLIVITDGRKQGDNLSYDSVIPMAEAASIIRYAIGVGKAFYNEHSKQELKAIASMPSHEYVFSVENFDALKDIENQLKEKIFAIEGTETPSSSTFELEMSQEGFSAVFTPDGPVLGAVGSFSWSGGAFLYPSNMRPTFINMSQENEDMRDAYLGYSTALAFWKGVHSLILGAPRHQHTGKVVIFTQESRHWRPKSEVRGTQIGSYFGASLCSVDMDRDGSTDLVLIGVPHYYEHTRGGQVSVCPMPGVGSRWHCGTTLHGEQGHPWGRFGAALTVLGDVNGDSLADVAIGAPGEEENRGAVYIFHGASRQDIAPSPSQRISASQIPSRIQYFGQSLSGGQDLTRDGLVDLAVGSKGRVLLLRTRPILRVSPTVHFTPAEISRSVFECQEQVAPEQTLSDATVCLHIHESPKTQLGDLRSTVTFDLALDHGRLSTRAIFKETKTRALTRVKTLGLNKHCESVKLLLPACVEDSVTPITLRLNFSLVGVPISSLQNLQPMLAVDDQTYFTASLPFEKNCGADHICQDDLSVVFGFPDLKTLVVGSDLELNVDVTVSNDGEDSYGTTVTLFYPVGLSFRRVAEGQVFLRKKEDQQWQRRGQHSLHLMCDSTPDRSQGLWSTSCSSRHVIFRGGSQMTFLVTFDVSPKAELGDRLLLRARVGSENNVPGTPKTTFQLELPVKYAVYTMISSHDQFTKYLNFSTSEKEKTSVVEHRFQVNNLGQRDVPVSINFWVPIELKGEAVWTVMVSHPQNPLTQCYRNRLKPTQFDLLTHMQKSPVLDCSIADCLHLRCDIPSLGILDELYFILKGNLSFGWISQTLQKKVLLLSEAEITFNTSVYSQLPGQEAFLRAQTKTVLEMYKVHNPVPLIVGSSVGGLLLLAIITAILYKAGFFKRQYKEMLEEANGQFVSDGTPTPQVAQ
What is the function of this protein?
Integrin alpha-X/beta-2 is a receptor for fibrinogen.  It recognizes the sequence G-P-R in fibrinogen.  It mediates cell-cell interaction during inflammatory responses.  It is especially important in monocyte adhesion and chemotaxis (By similarity).
What are the official names of this protein?
Integrin alpha-X, CD11 antigen-like family member C, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y4SM_SINFN
Sequence: MEVGLSPSACLRRIKLMEQAGVIRGYTALVDPTQSESTIAVIINITLERQTEEYLDKFEAAVRKHPEIRECYLMTGGSDYMLRVDVENAGAFERIHKEVLSTLPGVLRIHSSFSIRNVLAGRLKAKR
What is the function of this protein?
Not known, symbiotically active.
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator y4sM, ORF-1.
Protein: CAS2_MALDO
Sequence: MAALRSFLKKRSSVLCNGGAVRHRLFSAQVSQPIPDSPSFAQRIGNLPKDLPATQIKTQVSQLIGRTPIVYLNKVTEGCGAFIAVKQEMFQPTASIKDRPALSMINDAEEKGLITPGETTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVCMRCFGADLILTDPTKGMGGTVKKAYDLLESTPNAFMLQQFSNPANTKVHFETTGPEIWEDTNGQVDIFVMGIGSGGTVSGVGQYLKSKNPNVQIYGVEPAESNVLNGGKPGPHSITGNGVGFKPDILDMDMMERVIEVRSEDAVNMARQLALKEGLMVGISSGANTVAAMELAKKPENKGKLIVTVHASFGERYLSSVLFQDLRQEAENMQPVAVD
What is the function of this protein?
Probably involved in the detoxification of cyanide that arises from ethylene biosynthesis in ripening fruits.  Has only background level of in vitro cysteine synthase activity.
What are the official names of this protein?
L-3-cyanoalanine synthase 2, mitochondrial, MdCAS2.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: B4_XENLA
Sequence: MAPKKAVAAPEGGNKENAAVKGSSKVKVKRKSIKLVKTQSHPPTLSMVVEVLKKNTERKGTSVQAIRTRILSAHPTVDPLRLKFLLRTALNKGLEKGILIRPLNSSATGATGRFKLAKPVKTTKAGKENVASENVDPNAEQETQKKAPKKEKKAKTEKEPKGEKTKAVAKKAKEDSDEKPKVAKSKKDKEAKEVDKANKEAKEVDKANKEAKEVDKAPAKKPKAKTEAAKAEGGGKAKKEPPKAKAKDVKAQKDSTDEGAPVKAGKKGKKVTN
What are the official names of this protein?
Protein B4, Histone H1-like protein, Linker histone B4.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ACCD_YERPB
Sequence: MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELEPKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCFSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SOLUE
Sequence: MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVVREALERSATRLEDLAAIAVTVGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAVILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLGKTRDDAAGEAFDKVGKLLGFGYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARKALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVACNSGLRSAAYASRLPYAVHFPSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y559_MYCPN
Sequence: MASASKSWLPWRKMFKLGWASFVDPELAKTAFLEFAKQFYVTSSAGAILFDLKKSQGLDQLQAIEKTRKVIITEQFANQTGKWILFDKENTKRINSLAQEHITPLIKRILRLADFKNVLINVQHHKKLQKCLLWEINGLICLVESLQFMENPTAIMEWFQGLKKHCPNVAVVTISGQHKPVIEPSLTEYKAVFGSSLLSFHLDATTINNSHLVRQILEQIKIKATLKSNSKVAKS
What are the official names of this protein?
Uncharacterized protein MG381 homolog.
Protein: MFNA_HALMA
Sequence: MLQRAEPQDFERVLSSMCTVPHPSAREAAERFLATNPGDPGTYETIAGLEREAVEYLGDITGLSDPAGYVASGGTEANLQAIRIARNRADTDDPNVVAPVHAHFSFTKAADVLGVELRTAPAADYRVNMAAMAELVDEDTVCVVGVAGSTEYGYVDPIPAIADLAETVDALCHVDAAWGGFYLPFTDHDWHFGHADIDTMTIDPHKVGQAAVPAGGLLARDRTLLDELAVETPYLESTDQLTLTGTRSGAGVASAVAAMESLWPAGYRQQYETSMANADWLADQLSARGHDVVGPELPLVAADLSMPMTDELRDRGWRVSKTGAGEMRVVCMPHVTRSMLRSFVADLDWY
What is the function of this protein?
Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.
What are the official names of this protein?
Probable L-aspartate decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: IF2_SHEB2
Sequence: MADTTVEKLATEVGKSVERLIEQFSQAGIKKGQADNVTEAEKQQLLDYLKKQHGGENAPTKMTLQRKTVSTLSVAGNGGQSKDVKVEVRKTRTFVKRDANEATLKAEEEAKVEAEALAKAKAEAEAAAAVKAKAEADAKAKADAEAKAKAKAAAEVKVVKDMSPEAEAARLEAERLKAAQEAATKRKQDEEAAKAAETARLLAEEHSKRWAEEERQRLEAEKNGDHHITTSKVARAAEDTSDLDEEKRGRRARNKSNAKKRGGKDARDGREKHMRNRSTAPESMAHGFNKPVAAVSRDVRIGETVTVSELAHLMAVKATEIIKQMMKMGSMVTINQVLDQETAQMVAEEMGHKVVLIRENELEHQVLKDRDDEDGIKQESRAPVVTIMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAVNKMDKPEADIDRVKSELSQHGVMSEDWGGDNMFAFVSAKTGEGVDELLEGILLQAEVLELKAVRDGMAAGVVIESQLDKGRGPVATILVQEGTLRQGDIVLCGLEYGKIRAMKDENGRSITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMTEGEVKELNIVLKADVQGSLEAITDSLTGLSTDEVKVNIIARGVGALTETDATLAAASNAILVGFNVRADAQARKTIDSESVDLRYYSVIYNLIDEVRAAMTGMLSPEFKQQIIGLAEVRDVFKSPKLGAIAGCMVTEGTIKRSAPIRVLRDNVVIYEGELESLRRFKDDVAEVRNGMECGIGVKNYNDVRVGDQIEVFETVEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.