PharMolix/UniProtQA huggingface dataset:
Protein: NU107_MOUSE
Sequence: MDRSGFGGMSSPVIRDAEVTRTARKHSAHKRVLIQANQEDNFGTATPRSQIIPRTPSSFRQPFVTPSSRSLLRHPDISYILGTEGRSPRHTQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGLYTNTEHHSMTEDVNLSTVMLREDDPGEAASMSMFSDFLHSFLKHSSTTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLEEENMFAIAGINASEKMVVETLFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSHMGSTRPLVTELDPDAPIRQKLPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIRTSVMTQDDSEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDVDGLMDEFSKWLSKSGSSLPGHLLRFMTHLILFLRTLGLQTKEEVSIEVLKTYIQLLISEKHTSLIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENICKKDNGEFSHHDLAPSLDTGTTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKPTLLSQATFTEKVAYEHREKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEDDPERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.  Required for the assembly of peripheral proteins into the NPC.  May anchor NUP62 to the NPC.  Involved in nephrogenesis.
What are the official names of this protein?
Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup84/Nup107 family.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure. During mitosis, localizes to the kinetochores. Dissociates from the dissasembled NPC structure late during prophase of mitosis.
Protein: PHNW1_BURL3
Sequence: MPDPILLTPGPLTTSATTRHAMQHDWGSWDAAFNQLTASVCADLVAIAHGGDEYVCVPMQGSGTFSVEAALGTLVPRDGVVLVPDNGAYCARILKILGRLGIEAIALPFGEDAAVDPAAIEAAFAREPRITHVAQVHLETSAGVLNPLDDIAAVCRRHGKRLIVDAMSSFGALPITLAGSGIDALISASGKCLEGVPGMGFAIVRREALDASEGNSPSLALDLHDQYAYLLKTGQWRFTPPTHVIAALRAALDQYLAEGGQPARGARYVDNCRTLVESMHALGFTTFLDASVQAPVIVTFHAPDHPAYDFRRFYDAVRDAGFILYPGKLTQLETFRVGCIGAIDSNDIRRAVAAIAQAVESLGIAVQRA
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase 1, 2-aminoethylphosphonate aminotransferase 1, AEP transaminase 1, AEPT 1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: PURQ_ACAM1
Sequence: MKFGVLVFPGSNCDRDVVLVTRDLLKQPTRMVWHQETDISDLDVVVIPGGFSYGDYLRCGAISRFSPAMQATMAHAEQGKLVLGICNGFQVLTESGLLPGALVRNRDLHFICDRVPVRVERTNLPWTQAYQAGQVITLPIAHGEGCYYADPETLKQLQANQQILFRYCQPNGEITPDSNPNGSVENIAGICNRQGNVVGMMPHPERASDPTLGYTDGLLLFQGVLNSLMAQGVTA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_ALBFT
Sequence: MGDIVLSARAITKRFTEGRLDVTVLQGVDLDVRAGETLAIVGASGSGKSTLLHLMGGLDAPTSGSVFLHGQDLAHQSAAAQGRLRNQYLGFVYQFHHLLPEFSALDNVAMPLWIRRLAPAESTHTATEMLAKVGLQERLAHRPSELSGGERQRVAIARALVTRPACVLADEPTGNLDRSTANGVFELMLELARVQGTAFVMVTHDESLAERCSRRIRLVQGRLLEAF
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACH7_CAEEL
Sequence: MMLGGGGGCGAGGTWLGFLVFLAVSLRNHSTCEDIDAEDRLMVDLFRGYNSLVQPVRNRSELPMIVKIGMQLVLLINVDEKEQVMHTNVWLTMKWDDFQLKWDPRDYANITQIRVAPEKVWLPDIVLFNNADGNYEVSFMCNVLILSTGTVLWVPPAIYKSSCIIDVEFFPFDDQLCSLTFGSWTYNRDEIKLDFLTSDRVDFSEYSTSSIWDMMDGPAVLTSDRSRIEFQIRIRRKTLFYTVVLILPTVLMAFLNVTVFYLPTASGEKMGLTMNVLLSIVVFLLLVSKILPPTSSSIPLVAKYLLLTFVLNIITIMVTTIICNIYFRSPITHRLPPWVRKVFLDILPLLMCMQRPHRKNVIQRSHRRLLETGPSVEENPMRSGEHHPLCRHTHNQDSCRRVRIQSDELDDELSPEAQRAIDAIEFITENRRDEEITKQFRDDWKFIASVVDRFLLYGFFGATVGGTIGIIFTAPSVFETFDENATLVKLKQLYDMGLANDTVLGIF
What is the function of this protein?
Non-alpha subunit of nicotinic acetylcholine receptor (nAChR).  Involved in nAChR sensitivity to nicotine.
What are the official names of this protein?
Acetylcholine receptor subunit beta-type lev-1, Levamisole-resistant protein 1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Co-localizes with unc-29 and unc- 38 at nerve cord synapses.
Protein: MNME_SALTI
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPRYADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPGVRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDANDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVRNKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALAEAANHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELAV2_XENLA
Sequence: MAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTANCPNTINCSSPVESNNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITEGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKVNHTILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGGIKSRFSPMAIDGMTSLAGINFPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSKTHKA
What is the function of this protein?
Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs.  Required for the vegetal localization of vg1 mRNA.  Probably required for nervous system development.
What are the official names of this protein?
ELAV-like protein 2, Elav like-1, Xel-1, Protein ElrB, p45.
What is the protein family that this protein belongs to?
Belongs to the RRM elav family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Enriched at the vegetal cortex in stage III and IV oocytes. Shows both nuclear and cytoplasmic localization in the neural tube at the neurula stage, although endogenous elavl2 is not expressed at this stage.
Protein: MAGA9_HUMAN
Sequence: MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYGEPRKLLTQDWVQENYLEYRQVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV
What is the function of this protein?
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
What are the official names of this protein?
Melanoma-associated antigen 9, Cancer/testis antigen 1.9, CT1.9, MAGE-9 antigen.
Protein: COAX_TRIV2
Sequence: MISQQFPKHVENQWLALEIGNSRLHWALFMGESLKFTWDTEYLPESVIQQLGNGETNWELGTGEKGISSSTFPPLPPAPCPSGSQSLMGETPKTELSHPLPLFIASVVPKQTALWQSYPNVRVITLDQIPLNNTYPTLGIDRALALWGAGMSWGFPMLVIDAGTALTFTAADGERNLVGGAILPGVGLQFASLGQKTEQLPQVEMAEIKSLPPHFALNTAEAIQSGVIYTLIAGIRDFTEEWLSLFPDGKVAIKGGDRILLLNYLQALYPELAGRLIVEPNMIFWGMQTIVAGVA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_ALKEH
Sequence: MEMTADYLRDRAWQYAQLTRLNRPIGNFLLLWPMLWGLWIAAKGLPDLKVLVVFVLGVLIMRAAGCVINDYADRDFDGHVKRTTHRPMANGRVSEREALTLFVVLCLVAFGLVLLMNPLTIALSLVAVALAATYPFMKRYTHFPQVHLGAAFGWAIPMAFAAQTGAVAPVAWLLFLSAVLWATIYDTQYAMVDRDDDLKIGVKSTAVLFGQADRAIIGVLQGVMLAVLVAAGLVVGLGAFWYLGLAAAAALFAYQQWLIRERRREDCFRAFLNNNWLGGLIFLGLLLDLHLGG
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHAS_ECO8A
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_CLONN
Sequence: MPRKGNTPKRDVLPDPLYNNKVVAKLINSIMLDGKKGVAQKICYDAFAIMGEKTGKEPLEVFEEAMNNVMPLLEVKARRIGGATYQVPIEVRADRRQTLGIRWIVDASRKRGEKYMRERLAGELLDAANNTGAAVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RUTC_AGRRK
Sequence: MPKSIIVPAGTHKPIAPFSPGTLADGIVYVSGTLPFDKNNDVVHVGDAGAQTRHVLETIKSVIETAGGTMEDVTMNHIFVTDWANYQAVNAVYAEYFPGDKPARYCILCGLVKPDALVEIATVAHIGKK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: Y3437_KORVE
Sequence: MDLQGLKITWLGHATFRVVTPKGTHILIDPWVMGNPACPETEKQVKKVDVMLITHGHFDHIGDAVEIAKKHSPKVVCIPEMGAWLQKKGVKNVAEMNKGGTQHVGDIAVTMVHAVHSCGITDGDQVVYGGEACGYVLKFDNDVTLYHAGDTMAFSDMKIIHELWRPQIAMLPIGDHYTMDPRQAAYAAELLQPKAIIPMHFGTFPVLTGKPSELEKFVEVCDVHEMKPGETWS
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Acid345_3437.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: DAPB_SHELP
Sequence: MTEQVRVAITGGSGRMGRTLIESAKLSSNIYLGAAVERAGSTLIGVDAGELAGVGAMNVAITDSLDNAVDDFDILIDFTSPEASVVHTDWCSRNGKAIVIGTTGFNHAQKEQIAAYAENTPIVMAPNMSVGVNLMWRLLELAAEVMGDYTDIEIIEGHHRHKKDAPSGTALKMGEVIAEVLGRDLEKCAVYGREGITEERSRETIGFSTIRAGDLVGEHTAMFADIGERLEITHKASSRMTFANGAMRAAFWLGDQGPGLYDMQQVLGLKD
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ACTP2
Sequence: MSRVAKAPVNIPAGVEVKLNGQLLTVKGKNGELSREIHNAVEVNQDANALTFVPRTGVANADAQAGTARALVNAMVIGVTEGFTKKLQLVGVGYRAQMKGNVVALSLGYSHPIEHTLPAGVTGECPSQTEIVLKSADKQLIGQVAADIRAYRRPEPYKGKGVRYSDEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CHZ1_PICGU
Sequence: MAEEEKPPVSESIEDNKDDKKRTIDKVDDSVEDGAEKKPEAAVKNDGETAEKPEKKHKKRRRRQYEDEVPKEKSEDEGEDEEDEDDDGDEINDELADLDDEDDDDLAEIDPANIIPSGRRTRGKVIDFTKAAEKLKEEGKIEDDEGEDGEYGEK
What is the function of this protein?
Forms a chaperone-bound H2A. Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A. Z histone replacement in chromatin.
What are the official names of this protein?
Histone H2A.Z-specific chaperone CHZ1.
What is the protein family that this protein belongs to?
Belongs to the CHZ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSA7B_ARATH
Sequence: MARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSARKIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQSGGVRPFGLSTLIVGFDPYSRLPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKESSGQETIKLAIRALLEVVESGGKNIEVAVMTREETGLRQLEEAEIDAIVAKIEAEKAAAEAAKKGPPKET
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-B, 20S proteasome alpha subunit D-2, Proteasome component 6B, Proteasome component 6C, Proteasome subunit alpha type-4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GIP4_KLULA
Sequence: MLAKAAASASSSMEKGSVYLDFTDIKCIQYTSSIRKLEQLVHVCKVLLRNLSMKSNENLIPLSNIVIALGSGFQFNVSAAIEKRIELLSQFRSCKANATNLPLSTTSLKLEVDLVPVEEDSVLFVSKFYNKELQSQLLTTLQRVAEDSLQIYQARIRQLTMERNSNRPTDLSGRTTIFNEDALNDLLSPNELAFGLDLLVNIRNRSTDTSSSAFFALALPILEKFRSNLNDKCIPPIRSYYTSIMKFSRTKGVFSNNVLIQLPYWQFTLHRMYAASLRAKCLIDVIRAVLRQIYIPNKHHFHDNTTKLHSKNLHEYSELLEELETFCFTQELEKDLIEAFKSYGNQNTVYQVQFNNISSAYQRLLLKSTQMLRKAAKLVDSFSTQWKSISDNMKASKYDDMNIDEMAKMAEEKLAVDELAYNEKIKEQERQREEKKNSSLSQKNTSSSSSITSNSSSLNVSPNILSPLRLSRTSSVSRSEESRSPSSPIPFTDAKSNISAKKTRSVRTRNRSSSLQSVSSLEDTSTARNGMRSNSLQSGSLNTQRIVQNAYSKALLSLNEKRGPRLTPTKLNNSIRSKSPSPTVSRQNSVKQRNKVNILKLNEVDEDDINEKFHDLKLDDDTLIVSQEVLSPEGSETPKIIVSVADDNQSSSNNDSEVEGIVKKVRFIGVPPMSQDENPEPKRRGWYKKPAVLHYPPPPAQHSLQKFRTTQEGLAFRTSLISRDQGSDKKFGFDSMYSSGQGADTKIVGKIKDKLFK
What is the function of this protein?
GLC7 phosphatase-regulatory protein involved in GLC7 subcellular redistribution and chromosome segregation.
What are the official names of this protein?
GLC7-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the GIP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STAAM
Sequence: MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP4_YEAS7
Sequence: MAKKNRLNTTQRKTLRQKEDEYIENLKTKIDEYDPKITKAKFFKDLPISDPTLKGLRESSFIKLTEIQADSIPVSLQGHDVLAAAKTGSGKTLAFLVPVIEKLYREKWTEFDGLGALIISPTRELAMQIYEVLTKIGSHTSFSAGLVIGGKDVKFELERISRINILIGTPGRILQHLDQAVGLNTSNLQMLVLDEADRCLDMGFKKTLDAIVSTLSPSRQTLLFSATQSQSVADLARLSLTDYKTVGTHDVMDGSVNKEASTPETLQQFYIEVPLADKLDILFSFIKSHLKCKMIVFLSSSKQVHFVYETFRKMQPGISLMHLHGRQKQRARTETLDKFNRAQQVCLFATDVVARGIDFPAVDWVVQVDCPEDVDTYIHRVGRCARYGKKGKSLIMLTPQEQEAFLKRLNARKIEPGKLNIKQSKKKSIKPQLQSLLFKDPELKYLGQKAFISYVRSIYVQKDKQVFKFDELPTEEFAYSLGLPGAPKIKMKGMKTIEQAKERKNAPRQLAFLSKANEDGEVIEDKSKQPRTKYDKMFERKNQTILSEHYLNITKAQAQEDEDDDFISVKRKDHEINEAELPALTLPTSRRAQKKALSKKASLASKGNASKLIFDDEGEAHPVYELEDEEEFHKRGDAEVQKTEFLTKESAVMADIDNIDKQVAKEKKQEKKRKRLEAMRREMEAAMEEEISGDEEEGKTVAYLGTGNLSDDMSDGDMSDSEGHLKKKARTVDYSHGHNPSNSVDDDIIEVEEPQTLEDLESLTAKLIQG
What is the function of this protein?
ATP-dependent RNA helicase required for ribosome biogenesis.  Involved in the release of U14 snoRNA in pre-ribosomal complexes.  Required for pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP4, DEAD box protein 4, Helicase CA4, Helicase UF1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FTMC_NEOFI
Sequence: MPSVMKCGYLATAGLIGICIHLWYFRYGEHHLYPWRYVRFHLCLTMGVSALLYAKKPPQYTLSPGDLVKDTCLLMVTYLIGLFTSLLLYRTLFHPLRQIRGPWAAKVSSFWLSFRLRRGPSFRILHELHEEYGPVVRVGPSEVSIIHPEAIGIIYGPNSRCSKNAFYDNGHPMMSLHSYRDRTAHDQRRRVWSAGFGDRALRGYEQRMRVYRQKLFQRLEERADAESTINISQWFNFYSYDTMGDLAFARSFDMLDASRNHWAVDMLMHGMIGYRYLFPSWFFRLLATMPSLSNDWHKFIGFATDTMLRRLREQVGVPDIFASLLAPLNGRDPTDDERNMLMGDAMLIITAGSDTTATSLTSIVYELARRPDEVDKLRAEIEPIEADSDGEYQHDTLAKLPHLNGFINEAFRLHSPIPGVIPRKTPPEGIHVKDIFIPGNMTVFSPQWSMGRSEAAYVDPAIFNPERWYKHIDLVKEKSVFAPFSIGPYSCIGKPLAMMNIRTTVARLIMRFDVRFPEGEDGIRWMDAADEHFAMGIHQMPVVLTRRH
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities (PubMed:23109474).  The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmPS/ftmA (By similarity).  Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B (By similarity).  The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively (By similarity).  The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (By similarity).  FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B (By similarity).  Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties (By similarity).  Finally, verruculogen is further converted to fumitremorgin A by the verruculogen prenyltransferase ftmPT3 (PubMed:23109474).
What are the official names of this protein?
Tryprostatin B 6-hydroxylase, Fumitremorgin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HMUV_AGRFC
Sequence: MIRAENITLIRTGRRLLDDVSVDLKPGKVNVIIGPNGAGKSTLMKVLSGEMRAEGGSVTYNNVALPQFTPVQLARMRAVLPQNTQLAFPFTALEIVRMGAVAQGSRAPEEQARRALARAGLRGFEQRSYNMLSGGEQQRVQFARALAQVPNSVENGEARALFLDEPTASLDIGHQISVLETARDFASGGGLVLAILHDLNLAAEFADQLIVMHGGRVTASGPSLDTISDETIARVYGIGGVVGRLPARHIPYVLPQSRHR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNLJ2_STRGG
Sequence: MAGEDRVEQESSVPADVREKHALLAEQIEEHRFRYYVKDQPVVSDADFDRQLRSLEALEEEHPSLRTPDSPTQKVAGPYRTEFTSVEHRERMLSLDNAFDDEELAAWADRVAKDVGTPDHHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPNVRTIAEIPHRLKGEDIPALVEIRGEVFFPMEDFEELNARLVAADDKPFANPRNAAAGSLRQKDPKVTATRPLHMVVHGIGAHEGLSIDRLSAAYDLLHTWGLPTARHNKVVDSLAGVREFIAHYGENRHSVEHEIDGVVVKLDEIPLQGRLGSTSRAPRWAIAWKYAPEEVNTKLVNIRVGVGRTGRVTPYAQVEPVEVAGSEVEFATLHNQNVVKAKGVLIGDTVVIRKAGEVIPEILGPVVDLRDGTEKAFEMPTHCPECGTELRPMKEADIDLRCPNARTCPAQLRERVFYLAGRKSLDIDHFGYVAAAALTRPLEPAEPVLKDESDLFSLTVEQLLPIRAYVLDQDSGLPKRDPKTGEEKIATVFANQQGEPKKNAVAMLEGIAAAKDAPLARVLTGLSIRHVGPVAAQELARQFRSIERIDEATEEELAAADGVGPTIAASVKQWFAEDWHREIVRKWREAGVRMADEGSDEDEGPRPLEGLTVVVTGTLAGHTRDGAKEALQALGAKVAGSVSKKTAFVVVGDNPGSKYDKAMQLKVPVLDEDGFAILLEQGPERAKEAALPVPEAAPAADPENSGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase 2, Polydeoxyribonucleotide synthase [NAD(+)] 2.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TXF1A_ETHRU
Sequence: MQNKGVVLTLFLVVSMAIVISSTKEKRAVIQKKYVDFKDRKYPWKEECFETCARTFTNGDQSKVSEVVPDYFKCICYVLI
What are the official names of this protein?
U-scoloptoxin(15)-Er1a, U-SLPTX(15)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-15 family.
What are the subcellular locations of this protein?
Secreted.