PharMolix/UniProtQA huggingface dataset:
Protein: TBD_HUMAN
Sequence: MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGIDRHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLKPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL
What is the function of this protein?
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
What are the official names of this protein?
Tubulin delta chain, Delta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Note=Associated with centrioles. Both cytoplasmic and nuclear. In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.
Protein: GATA_NEIMF
Sequence: MTQYTLKQASVLLQSKQISAVELASAYLAAIAEKNPALNGYITIDQDKTLAEARAADERIAQGNASALTGVPVAYKDIFCQTGWRSACASKMLDNFISPYTATVVQNLLDEGMVTLGRTNMDEFAMGSTNENSFYGAAKNPWNPEHVPGGSSGGSAAVVAARLAPAALGSDTGGSIRQPASHCGITGIKPTYGTVSRFGMVAYASSFDQAGPMAQTAEDCAILLNAITGFDPKDSTSLEREKEDYTRDLNQPLKGVKIGLPKEYFGEGNSADVLTALQNTIDLLKAQGAELIEVSLPQTKLSIPAYYVLASAEAGTNLSRYDGVRYGHRAAQFADLEEMYGKTRAEGFGSEVKRRIMIGTYVLSHGYYDAYYLKAQKLRRLVADDFQTAFARCDLILAPTAPTAAPKIGADASPVETYLSDIYTIAVNLAGLPALTLPAGFSGGGLPVGVQLVGNYFAEAKILGAAHQIQLNSDWHGKRPE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS16_NATTJ
Sequence: MAVRMRLKRMGAKKQPSYRIVVADVRAPRDGRFIEELGHYNPTTEPVTLEINEEKAKKWLQEGAKPSQKVRSLLTQAGVVEK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CSGC_ECOLI
Sequence: MNTLLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQILSLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQWPPSSEKS
What is the function of this protein?
Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers.  Assembly may also require CsgE.  Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity).
What are the official names of this protein?
Curli assembly protein CsgC.
What is the protein family that this protein belongs to?
Belongs to the CsgC/AgfC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPXC_SHIDS
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: YO07_BPS2
Sequence: MATKNRTIIKKYADRWHKEACHLYAKWLNAKRQGDEEAANYYFSKYITAGDNWINYTKFAH
What are the official names of this protein?
Uncharacterized 7.3 kDa protein in cox-rep intergenic region, ORF23, ORF7.
Protein: KATG1_BURO0
Sequence: MSNETKCPFNHTAGSGTTNKDWWPNQLNLNVLHRHSALSDPMDPDFDYAEAFKKLDLAAVKQDLHALMTTSQDWWPADFGHYGGLFVRMAWHSAGTYRTADGRGGAGGGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRNISWADLLILTGNVALESMGFKTFGYAGGRADTWEPDDVYWGSEKIWLELSGGPNSRYTGKRELESPLAAVQMGLIYVNPEGPDGNPDPVAAAHDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGPEPEAAGLEEQGLGWKSTFGTGKGKDTITSGLEVTWTSTPTKWSNDFFKHLFSYEWELTKSPAGAHQWVAKDAGEVIPDAYDASKKHRPTMLTTDLSLRFDPAYEKISRRFYENPAEFADAFARAWFKLTHRDMGPRARYLGPEVPAEHLLWQDPIPAVDHPLIDAADVAALKAKVLATGLSVSQLVSTAWASAATFRGSDKRGGANGARIRLAPQKDWEVNQPVALAAVLETLEGVQKAFNDAQTDGKKVSLADLIVLAGAAGVEQAAKNAGISISVPFAPGRMDASQEETDVDAMAVLEPVADGFRNYLKSAYKTPAEALLVDKAQLLTLTAPEMTVLVGGLRVLGANVGDSKHGVFTDRPGTLSNDFFANLLDMGTEWKPVSAANDVFEGRDRATGAVKWTGTRVDLIFGSHSQLRALAEVYGSADAQEKFVRDFVAAWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PAM17_USTMA
Sequence: MPVAIAAARYAALSAGASSSRSAIMLSSSHRALSTSSKVASSSSSSNRGTFSPTSPILFSASSSSSSSSSPSSSRELSHLSWDKYLQLRRSRRLAGMVTTIPTTLLAGAAAGSYFLTLELDPTNAIAGLDPVYINAGLTLACTGLGWLIGPTVGNSIWGLLHRSDAKQIAQKDHDFYEHIKRNRVDPTRQSVQNPVPDYYGEKIGSIKQYRQWLRDQAAFRRKAAHGLEQDA
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPO4_ACET2
Sequence: MKRVILHCDLNNFYASVECLYHPELRDKPVAVCGSIEDRHGIVLAKNYAAKKYKVKTGETVWEAKNKCPGLVVVKANHSLYYKFSKYARQIYEYYTDRVESFGLDECWLDVSESTLLFGDGTKIANEIRERIKRELGVTVSVGVSYNKVFAKLGSDMKKPDAVTVITENDFKEKIWGLPVEALLYVGDSTKKKLNNMAVFTIGDLANCHSEFLVRQLGKWGYTLWSFANGYDTSPVAKNDCEIPIKSIGNSLTAPRDLTNNEDVRILIYVLSESVGERLRSHNLKGRTVQISIKDPELQTLERQAGLDIHTSITSEIAQKAYEIFLKSWNWSKNVRALGVRVTDLVESDTCTQISLFSDDIKRQKLEILDECVDRVRERFGYYSVRRGILLQDRGLNRI
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO040_MOUSE
Sequence: MPKKAGATSKGKNQTKEPETAPPAAGPVATDPKGFVTIAIHAKPGSRQNAVTDLSTEAVGVAIAAPPSEGEANAELCRYLSKVLDLRKSDVVLDKGGKSREKVVKLLASTTPEEVLEKLKTEAEKK
What are the official names of this protein?
UPF0235 protein C15orf40 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: FOLD_ALCBS
Sequence: MTAQILDGKTLAQQFEQEMRLRVDVLKAKANGHTPILATILVGADPASATYVKMKGNACQRVGMESVAIELSEETTTAQLLAKIDELNNNQDVHGILLQHPVPAQIDERACFDAISLEKDVDGVTCLGFGRMSMGEAAYGCATPKGIMRLLEHYQVELEGKHAVVVGRSAILGKPMAMMMLEANATVTICHSRTQNLPELVKQADIVVGAVGKPEFIKADWIKDGAVVVDAGFHPERCGDIELAPLVDRVAAYTPVPGGVGPMTINTLIFQTLQSGEKAFG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: C3AR_PONAB
Sequence: MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTVWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCELIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGTACSICGCIWVVAFVMCIPVFVYREIFTADNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQLPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLHRDSARLTSQNLYSNVFKPADVVSPKIPSGFPIKDQETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQDFQDYYNLGQFEDDNQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLIDPESPLGKTLMSWDHVSIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCNSNNVFSERNSTTV
What is the function of this protein?
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a.  This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).
What are the official names of this protein?
C3a anaphylatoxin chemotactic receptor, C3AR, C3a-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3A_CULQU
Sequence: MSRYMQRPENALKRANEFIEVGKPARALDTLQEVFRIKKWTYTWSEAVIEPIMFKYLDLCVELKKSHIAKEGLFQYRNMFQMLNVGSLENVIRGYLKMAEERTEAAQQQSSQAILDIDDLDNLATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYGQCLELLKVNSHCENLYHDIAKMAFAFCLKYNRKMEFRKLCEKLRKHLDDISKVSSQTANVSISKPETQQLNLDTRLNQLDCAIQMELWLEAYKAIEDIHGLMTLSKKTPMPKTMALYYQKLAMVFWKAGNQLFHAAALLKLFQLSRDMKKNVTQEEIQRMTSHVLIATLAIPLPSAHPEFDRFIETDKSPLEKAQKLAVLLGLQQPPSRVSLLKEVLRLNVLQLAAPQFQNLYKWLEVEFDPLNLCSRVQGVIEEITADENSPYTQYTQALQDVTLVRLVRQVSQVYQSIEFSRFLSLAKFANSFYLERILVDCVRHNDMQITIDHRNHSVHFGTDLSESQREDHPDGPTLQSMPSEQVRSQLVNMSVVLHRAIATINPNRKKADRERLRNQMVKNYEENMVKDHQRILQRQKKIEDRKEYIERVNLEREELEQRQLEEAARQQKLAEMRRLEQENEERERKRHENEIQMIKERNMKDKIDQIKQSASGQKLLKKIDEEDIKKMNAEEIAAKEAEERQKERKAHDNNLKSQEKKIDYFERAKRLEEIPLIEKYLEDKLVQDKEFWEKQEASRIEAAIAERKNAEQVQERLRRMQADRDVFWQKLKGERSNAFAEKLKVFNAALEEERRRRLAERVIQRREERRQKWLREKEEERRRIEEELRKQREEEERIERERRAEERRIENEKQRVIMEKQRAKEEEIERKLAEEKERLKERAPRGEKEERGGGGGGGGAWRGRGDTAAPAESAAKPESDWRNAREAREPAPESAGASSAAAPAPKKDGVWQPSGRFREGRGAPGADRPPRGDDREPPAAAAGESKWRRGGGGADDDKDDGPRPRVGAGDRGPMRRGDGDRDDRGPMRRGDRPPMRDGDRPGMRRDDRGDRREGGAPDRRDFGGRGGDRRDDRRDDRGPRREGGGERGGDVWRRAPQEDRRGGAAGGESGGNWRNARQAEPAKPREERRGGEERPKEARAAAGPDEDGWTDVKHHR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_FRATF
Sequence: MSKLTIVRGFNDVLPLDSYKWQFLESKVKLILDRYNYSETRLPIVERSELFHRSVGESSDIVSKETYDFQDRNGDSLTLRPEGTAGCVRMVIENNLATRGQTQKLWYCGPMFRYERPQKGRYRQFYQLGVEAYGFDGIAIDLEVIAIAWSLFKELGISEYVTLELNSLGSSLNRQEYTQALLQYLKPYHAELDEDSIKRLDKNPLRILDSKIEKTQKILANAPKLIDFIDHDLRLRFKQTCQYLDALGVRYKLNENLVRGLDYYTGLVFEWTTDKLGSQSAICAGGRYDGLVENLGGQKTAAIGFAIGMERLLLLLEDLGKLPNQDNACDVFFILDSAQLHQSLAIVENIRQELPQLKIDMDLKFGSFKSQFKKADKSGAKVAIIIGQDELDNGFAGIKFLQQNEEQQQVAFNELINFLER
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_SYNP6
Sequence: MMEASPGLSIAITFAVILLALTGFSIYTSFGPPSKQLEDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TNR11_HUMAN
Sequence: MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA
What is the function of this protein?
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis.  Involved in the regulation of interactions between T-cells and dendritic cells.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform RANK-e5a]: Cell membrane; Single-pass type I membrane protein.
Protein: NB2_MYCMM
Sequence: MPADLHPDLDALAPLLGTWAGQGSGEYPTIEPFEYLEEVVFSHVGKPFLVYAQKTRAVADGAPLHAETGYLRVPKPGQVELVLAHPSGITEIEVGTYSASGGVIEMEMVTTAIGMTPTAKEVTALSRSFRMVGDELSYRLRMGAVGLPLQHHLGARLRRKS
What is the function of this protein?
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate.  Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively).  Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
What are the official names of this protein?
Peroxynitrite isomerase 2, Ferric nitrobindin, Nb(III).
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: POLG_PWVTB
Sequence: KDEIIDVGADGKKVVSKKDTQDAGEVNKGKEKDKDVNAGSKGSGVPRLQKITKKMNLPMVKGNMVLDLDHLIEYKPDQTKLFNTRATDAQFATWYEGVKAEYELSDDQMGVIMNPFMVWCIENGTSPDINGVWVMMDGDEQVEYPLKPMVENAKPTLRQIMHHFSDAAEAYIEMRCASGPYMPRYGLLRNLRDKNLARYAFDFYEVNAKTSDRAREAVAQMKAAALSNVTNKLFGLDGNVATISEDTERHTARDVNQNMHTLLGMGAPQ
What is the function of this protein?
Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae genome polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion.
Protein: ARGA_PECCP
Sequence: MKERSTELVQGFRHSVPYINAHRGKTFVIMLGGEAIEHANFSSIVNDIGLLHSLGIKLVVVYGARPQIDANLTTHHYEPHYHKNTRITDSTTLELVKQAAGMLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAVHRQLNSGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTNEEGSIISELFPDDAQRRIDTLEQAGDYHSGTVRFLRGAVKACRSGVRRSHLISYQDDGALLQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEEQGILVRRSREQLEMEIDKFTVVVRDNLTIACAALYPFPEESIGEMACVAVHPDYRSSSRGDMLLMRIAAQARQQGLQKLFVLTTHSIHWFQERGFLPAEVEMLPKKKQALYNYQRRSKILVLDL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_DESVH
Sequence: MARLRLTIAYKGTDLHGWQVQEHATRPRPRTVQGVLEPIVSRMAGEQVRLHAAGRTDAGVHADGQVAHVDIPDHKLGVDWQKAINAQLPDDICILDVRRAADDFHARFDALGKRYTYRLWLTRRFIPPKLHGQVWATGPLDVYAMDRAARHLAGTHDFAAFQNQGTDVTSTVRTVHAIRRCPSGTLPAGALLTCSEPYTSWRCTGTHPDQPPATAGHPLAGIGLELVWSFEGDGFLKQMVRNMMGLLVAVGRGALAADDVPGIMATLDRSRAPATAPACGLTLSEVYYPPCDYPYAR
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PYRF_METCA
Sequence: MPNFLSNKPIPVADRLIMALDLPDVSEAKTLVERLGDAVSFYKVGLELFMSGDCFALVDWLKAKDKKVFVDLKFFDVPETVGRAVKALSRRGVDFATVHGNDAIMEAAARNKGSLGILAVTVLTSLDQGDLRDLGFQCDVQELVLSRARRALAVGCDGVVSSGLEVPLLRGEIDHELMVVSPGIRPVENRPEDDQKRVVTVDQAFRNGADYIVVGRPIRDAADPREAAQRAQAQIRDVFAAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: LOR2_ARATH
Sequence: MQIYNPISPVKTMVKIYPHLAFPVDMDVVQDKILPYLTTEQERFTIWMKSLVFNSKGCTVFDSKGNLIYRVDNYDSKSWSNEVYFMDLNGKILFTLRQKKLGFFKSWEGYNSTGTRFRLRKIFKILPRESSSSYKVVMGSRIVDGDQQSCYKIVNRGSVFAIKDGSGRLMAEVKNKLSDISGLDLGDDVLTMMVEPQLDHSLIMGIVIAYKLTKCKL
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 2.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: DMC1_MOUSE
Sequence: MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE
What is the function of this protein?
Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
What are the official names of this protein?
Meiotic recombination protein DMC1/LIM15 homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RK22_CYACA
Sequence: MKATIRFIKISPTKVRRITNQIKGLKYADACILLKFMKGRIAKTILKLVNSAFSNSRYSTFADLRIQTVLVEKGPIFNRFQPRAKGRAYPIKKYTSHIKVVLS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KATG_MARMS
Sequence: MSKENMSNEGKCPFNHGAAGTNQSSGRGTSNKDWWPNQLNLNILHQHSPKSNPMGEDFDYAKEFNSLDLEAIRQDLFALMTDSQDWWPADYGHYGPFFIRMAWHSAGTYRTADGRGGATSGTQRFAPLNSWPDNVNLDKARRLLWPIKQKYGRKISWADLMILAGNCALESMGFKTFGFAGGRVDVWQPEEDIYWGTEKTWLDDERYTGDRELENPLAAVQMGLIYVNPEGPEGKPDTLASARDIRDTFGRMAMNDEETVALIAGGHTFGKAHGAGDAAQVGADPEAAGIAEQGFGWSNSMGTGKGVDTISSGLEGAWTKSPIAWDNGYFENLFEYDWELTKSPAGAWQWTPKDGAAANSVPDAHDSSKRHAPIMFTSDLALRDDPIYAPISKRFYENPDQLADAFARAWFKLTHRDMGPVARYLGPLVPQEELVWQDPIPAVTYVTVNDQDILDLKAKIQASGLTVAQLVSTAWASASTYRGSDMRGGANGARIRLAPQKDWAVNQPEQLAKVLSVLESIQAEFNRQDSTKQVSLADLIVLGGSVGVEQAAKASGHSVTVPFTAGRADASQEQTDVESFAFLEPAADGFRNYLKGKYTVSAEEMLVDRAQLLTLSAPEMTALLGGLRVLNANVGQSQHGVFTDKPETLSNDFFVNLLDMGTKWFATSEEEEEFQGRDRTTGKIKWTATRADLVFGSNSQLRAIAEVYACSDSQERFVKDFIAAWTKVMELDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: JMJD7_HUMAN
Sequence: MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD
What is the function of this protein?
Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase (PubMed:28847961, PubMed:29915238).  Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation (PubMed:28847961).  Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4 (PubMed:28847961).  After initial cleavage, continues to digest histones tails via its aminopeptidase activity (PubMed:28847961).  Additionally, may play a role in protein biosynthesis by modifying the translation machinery (PubMed:29915238).  Acts as Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA) (PubMed:29915238).
What are the official names of this protein?
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7, JmjC domain-containing protein 7, Jumonji domain-containing protein 7, L-lysine (3S)-hydroxylase JMJD7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SYFB_LACAC
Sequence: MLVSYNWLQDFLNLDQEPHALAEKITRTGVEIADVKHPEEGLKKLVVGKVIDCEGVEGTHLHLTHVDVGEDEPLQIVCGAPNVAAGELVIVALHGARIAGNEKIKKGKIRGIESYGMICGLQEIGFSDSVVPEEFADGIYVFPEDADVKPGQDVYEALGMDDYILDFDITPNRADTLGMEGAAYEVGAIVDQKPKIGDVVLKEDGPDWTSSLEANVDEKLAPKFYLRKLTGVKIQPSPLWMQRRLWNAGIRPINNVVDVTNYVMLLTGQPMHAYDAKTFETGKLEVRLANKGEKLTLLNEKEVELDPRDIIITDGEKPVMMAGVMGGLNSEITSETTDVILESAIFDPTLVRKSALRHANRTEASSRYEKGVNWDATEKAINMAALLLRNDAQATIDEGIIKATDTKREPVVVKTTVSHINDVLGSEISAEEMIKIFDRLGFVVDQDGDNIAVHVPNRRWDISIPADLVEEVGRIYGYDNLKSTQPLLAETHGGYSEKEEMMRRMKAIVEGQGLMEAISYSLTSPEKAVRYTKDPKDIVKVQMPLNSSRSVMRQNLMTGLVDAASYNFARKQTQLALFEQGRVYDHEGGTFNEHEHLAALYSGNTFAENWQHLTQKVDFYFVKGQLTNLFTAIGIDPEKVTYEAAPILGMHPTRTAAIYIDKQYVGMIGMIAHAVTLADKALRGAELYGYEINLDTIIPMLTKGMTAVPAPKFPAIERDLSLLVDKEITNQEVENVIKSNAGKYLVDLKVIDVYEGSHIAIGKKSFAYNLTFLNRKDTLTDKVVNNAMDKIIAGLENDLDIKVR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSUA_VIBCH
Sequence: MRLDKFLCDALGTTRKEATQLLKSGEVTVDDVVQKSGAFKLKETSCVEWQGREITLHGPRYIMMHKPDGVVCSHEDGFNQTALTLLDEVNIQDLHFAGRLDVDTTGLLLITDDGQWSHRVTSPKHKCEKTYRVWLADPIQADYAEQFNRGIELRGERELTLPAQLEVISETEVLLTIHEGKYHQVKRMFAALGNKVIGLHRERIGQITLDETLEPGEYRYLTEEEVASIWK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
What are the official names of this protein?
Ribosomal small subunit pseudouridine synthase A, 16S pseudouridylate 516 synthase, 16S rRNA pseudouridine(516) synthase, rRNA pseudouridylate synthase A, rRNA-uridine isomerase A.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.