PharMolix/UniProtQA huggingface dataset:
Protein: IPP2_HUMAN
Sequence: MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS
What is the function of this protein?
Inhibitor of protein-phosphatase 1.
What are the official names of this protein?
Protein phosphatase inhibitor 2, IPP-2.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 2 family.
Protein: HIS5_ECOL6
Sequence: MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_BIFLO
Sequence: MATTAGAKKGLWSTIRRIAASDRISGLIMLGFALTGLVLANLPATAHAFETVAETHLFIPYTNLDLPIGHWAQDGLLTIFFLTVGLELKQELTTGSLANPKAAAVPMLCAVGGMIAPPILFLAVTALFSQIGPGEPGTLILTTTGSSIPFSEMSHGWAVPTATDIAFSLAVLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSINAWYWFIGIAVCAAIWAYLVRLKKVPWIAVGIVGILAWIMMFEAGVHPTLAGVLVGLLTPSREMHGELSPRAERYANKLQPFSALLALPIFALFATGVHFESMSPLLLASPLVIALIVALVVGKPLGIITTAWLSTHVGGLKMAKGLRVRDMIPAAVACGIGFTVSFLIASLAYKNAELSAEARFGVLVASLIAAAISGVLLSRQSKRFEKTAAAAAADEEDDESIDGDGIGQPSHTTEPTTPTEHPGTLADGTASVEIDFRH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURT_PYRFU
Sequence: MIKLRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNAKATWIAMHRERLRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVRGPEDIPKAWEEAKTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVSGYSPRFRGLAKALSVPNATIRLFGKPEAYPGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHSQDYEKRKHLL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: AOXB_MACFA
Sequence: MRCASRSDELVFFVNGRKVMERNVDPEGTLLTFLRKNLRLTGTKYACGRGGCGACTVMVSKHDPVSRKIQRHFSVTACLMPICSLYGAAVTTVEGVGSIKTRLHPVQERIAKSHGTQCGFCTPGMVMSMYTLLRNHPQPSEEQLTEALGGNLCRCTGYRPILESGRTFCMESNSCQQKGTGKCCLDWGENDSSRLGKKNEICTKLFAKEEFQSLDPTQELIFPPELLRMAENPEKRTLTFYGERVTWISPGTLKDLLELKVKHPEAPLVVGNTSLGPAMKSQRQFHPVLLSPARISELSMVTKTSDGLTIGAGCSLAQTQDILAERIAELPEEKTQTYRALLKHLRSLAGQQIRNMASLGGHVISRHCCSDLNPVLAVSNATLNLISAEGTRQIPLNEHFLAGLASADLKPEEILESVHIPHSQKWEFVSAFRQAQCQQNALPHVNAGMRVLLKEGTDSIEDLSIAYGGVGAATISAHRSCQQLLGRRWNELMLDEACRLLLDEVSLPGSAPGGRVEFKRTLVVSFLFKFYLEVLQELKKLVKLFSVAVGADSRHRSEVSDQFLSALEDFPVTIPQGVQTYQNVDPHQPLQDPVGRPIMHLSALKHATGEAMFCDDIPVVDKELFMALVTSSRAHAKIISIDVSKALELPEVVDVITAEDIPGTNGAEGDKLLAVEEVTCVGQIICAVVAETDVQAKRATEKIEITYEDLEPVIFTIKDAIKHNSFLCPEKKLEQGNVEEAFEKVDQTIEGEVHVGGQEHFYMETQRVLVIPKTEDKELDIYVSTQDPAHVQKTVSSTLNIPINRITCHVKRVGGGFGGKVGKPAVFGAIAAVGAIKTGHPIRLVLDREDDMLITGGRHPLFGKYKVGFTNNGRIKALDIECYINGGCTLDDSELVTEFLILKLENAYKIRNLRFRGRACMTNLPSNTAFRGFGFPQGALVTESCITAVAAKCGLPPEKIREKNMYKTVDKTIYKQAFNPETLIRCWNECLDKSSFHSRRMQVEEFNKKNYWKKKGIAIIPMKFSVGFAATSYHQAAALVHIYTDGSVLVTHGGNELGQGIHTKMLQVASRELKIPMSCIHISETSTATVPNTIATAASVGADVNGRAVQNACQILLKRLEPIIKKHPEGTWENWIEAAFEQRISLSATGYFRGYKAFMDWEKGVGDPFPYYVYGAACSEVEIDCLTGAHKKIRTDIIMDACCSLNPAIDIGQIEGSFIQGMGLYTTEELKYSPEGILYSRSPDEYKIPTITDVPEEFNVSLLPSSQTPLTIYSSKGLGESGMFLGSSVFFAIADAVATVRRERDIAEDFMVQSPATPERVRMACADRFTKMIPRDDPETFKPWSIPIA
What is the function of this protein?
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal.
What are the official names of this protein?
Aldehyde oxidase 2, Aldehyde oxidase homolog 3, Azaheterocycle hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMA5_MOUSE
Sequence: MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Importin subunit alpha-5, Importin alpha-S1, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-beta.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MMS22_HUMAN
Sequence: MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNLDPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLHCKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLYIGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT
What is the function of this protein?
Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks (PubMed:21055983, PubMed:21055984, PubMed:21055985, PubMed:21113133, PubMed:26527279, PubMed:27338793, PubMed:29478807).  The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication (PubMed:21055983, PubMed:21055984, PubMed:21055985, PubMed:27797818).  It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs (PubMed:21055983, PubMed:21055984, PubMed:21055985, PubMed:29478807).  Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination (PubMed:27797818, PubMed:29478807).  Within the complex, MMS22L acts by binding ssDNA (PubMed:27797818).
What are the official names of this protein?
Protein MMS22-like, Methyl methanesulfonate-sensitivity protein 22-like.
What is the protein family that this protein belongs to?
Belongs to the MMS22 family. MMS22L subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to DNA damage sites, accumulates at stressed replication forks (PubMed:21055983, PubMed:21055984, PubMed:27797818). Recruited to stalled or collapsed replication forks; directly binds replication protein A complex (RPA/RP-A)-coated single-stranded DNA (ssDNA) (PubMed:27797818).
Protein: ARGE_VIBPA
Sequence: MQLPTFLEVYEGLISTSSISSTDPSWDQGNAKVIEKLATWFKDLGFHVEVIEVESGKHNMIARMGEGEGGLLLAGHSDTVPFDEGRWSFDPHKLTEKDNRFYGLGTADMKGFFAFIYEAVKKVDWSKQNKPLYVLATCDEETTMLGARHFTTNAPFKPDYCIIGEPTSLVPIRGHKGHVANAIRVTGKSGHSSDPALGVNAIEIMHEVLFAMMQLRDKLIKEYHHPGFAIPSPTLNLGHIHGGDSANRICGCCELHYDVRPLPGISLDGLENMLRSALQEVEAKWPGRIDIVPLHEPIPGYECQHDHPFIGGVEEICQTSSQTVNYCTEAPFLQQLCPTLVLGPGSIEQAHQPDEFLSFDFIDPTIDVLSKAMVKYCC
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ORITI
Sequence: MSILSLITAPDPILKKVASPVDTVNDSIRQLMDDMLETMYHNHGVGLAAPQVAVSKRIIVLDLSKVDIKEDNITNSEYKYPLFMVNPIVKAISNQTATAKEGCLSLPKQAIEVSRYHEIQVTYLDYYNKLTTLNAEGWLARAIQHEVDHLDGILLVDYLSNLKKEAALNTLSKIKDAAYDK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: VATA_THET8
Sequence: MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEAMKEIQGAFKALA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SSRP_MACCJ
Sequence: MPKGTGKVLAQNRKASHDYIIEETIEAGIELKGTEIKSIRRGSANLRDSYARVYKGEVFVYNMHIAPYEEGNRFNHDPLRTRKLLLKRKQIDKLFGQTREQGYTLVPLKLYIKNGYCKMLIGVAKGKKDYDKRHALKAKEAKREMDRAMKERY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: BPT_BRUA2
Sequence: MTHQPQQSPQFFLTAPSPCPYLEGQQERKVFTHLVGDKANEINDLLTQGGFRRSQNIAYRPACEVCRACISVRILAGEFEMTRNMRRVWSQNRDLIGRVHKAQPSTEQYALFRDYLDARHRSGGMSDMTVLDYAMMIEDTHVNTQIIEYRRRGPDSFMSAKGDGELIAVALTDVMADGLSMVYSFFLPHMQERSLGTYMILDHIERARAAGLPHVYLGYWVEGSRKMQYKIRFTPQEHLGPRGWQRFEG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_PHOPR
Sequence: MSKLDAYFGEFGGQYVPQILVPALDQLEDAFIEAQQDPAFQKEFIDLLKDYAGRPTALTLCQNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCRVYMGAKDIERQSPNVFRMKLMGATVIPVHSGSSTLKDACNEAMRDWSATYEEAHYLLGTAAGPHPFPTIVREFQRIIGEETKVQILEKEGRLPDAVIACVGGGSNAIGMFADFIDEKDVSLIGVEPAGKGLDTKMHGAPLKHGKLGIFFGMKAPLMQDEHGQVEESYSVSAGLDFPSVGPQHAHLNAIGRAEYGSVTDDEALDAFQLLARKEGIIPALESAHALAYALKMIEAEPEKEQLLVVNLSGRGDKDIFTVHDILDAKGVL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: DUS6_BOVIN
Sequence: MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGSLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPTQQLYFTTPSNQNVYQVDSLQST
What is the function of this protein?
Inactivates MAP kinases.  Has a specificity for the ERK family.  Plays an important role in alleviating chronic postoperative pain.  Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia.  Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain.
What are the official names of this protein?
Dual specificity protein phosphatase 6.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BACC3
Sequence: MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEMDGIPHYMVDIKNPEESFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDAIYREQMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHTSGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDIMMDQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFEDRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQLKSNNSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS19_BACTN
Sequence: MSRSLKKGPYINVKLEKRIFAMNESGKKVVVKTWARASMISPDFVGHTVAVHNGNKFIPVYVTENMVGHKLGEFAPTRTFRGHAGNKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PYRE_BRUME
Sequence: MNTDDVLAVFREAGAILEGHFILTSGLRSPVFLQKARVFMHADKTEKLCKALAEKIRAADLGPIDYVVGPAIGGLIPSYETSRHLGVPSVWVERENGVFRLRRFDVPKGARVVIVEDIVTTGLSIRETIDCMKDLGIEVVAAACIVDRSAGKADVGTRLISLAEYEVPAYPADKLPPELAAIPAVKPGSRNI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RIMP_STRP7
Sequence: MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVDKPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGKYIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI214_CUCSA
Sequence: MILKSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRAWLMEEGTEKKVSATTGFITGQLMMFISIYYAPLHLALGRPYTITVLALPYLLFHFFWTNPKHFFYYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFILPSSMLVRLVNISMFRCNNKMLFVTSSFVGWLIGHILFMKSVGLILVWIQQNNSIISKKYIRSNKYLVSELRNSIAPIFSIILFITWVYYLGRIPSPIPLKETSKTSETAETEESEEETDVEIETTSETKGTKQEQEGSTEEDTSPSLFSEEKEDPDKIDETEEIRIDKKEKYLFGFEKPLGIILFDYKRWNRPFRYIKNDKFDNAVRKEMSQYFFYTCQSDGKDRIVFTYPPSVATFFELIEKKISLFSTEKLFYDEFDNPWKSLNEQKKRILNKIVITRILLLDKGSPTLVGDVLQKRTQLCICNDETKKEYLPKIYDPFLSGPYRRRINLLLGFSMLNETSRKNDSENIWTNKIHAIIRNNNNGFFDGVTIPYKANASDQNSIDLTEISKKVPRWSYKLIKEIEQVYDITDGELVLDYQIRSRKCKRVVILSDLNKIKKISTSTPTSTPTSTPTSTSTPTSTPTSTPTSTPTSTSTSTPASIPASTSTSIPASTSTSTSTSIPASTSTSTSIPASTSTSIPASTSTSTSTSTSIPASTSTSTNEIKSKDEPKDEPMEQAIIRYAKQWDFRREIIKGSMRAQRRKMGIYQLFQGANSYLFLDRHNFFFSDFCIYIPRLMEKLDRLRIRTNTELPISNNGEEKTREDLKNEKNQESINLKEEKHIQIAELWESIRFGQLVRGSLLITQAFLRKYIILPSVIIAANLTRILLLSPPHFFEDFKNWKKEIYVKCTYNAIPLAENEFPQNWLTDGIQIKILFPFRLQSWHRSKKIEKKDFCFLTVFGTETEQPFGSAENPFLFFKSDLIELREFIKKKKQQLKKWRTKYFRIFLRLRKKVFRKINIAKEKWVIKPILFIKKRIREFWQRNPILLLQLKEIYKLTEAKKENNSIISNGMIQSSSGSIDSIILSLRERKMKELTDRINTMLKIIEKMKKDRQKELLNTKINISPNKMSYYDKIFESQKNILKILKKRNVRFIRKSYKFLKFFVQNIYIDIFQGIINMSRINGQDSKITKSFFNNEANQERIDKPNQSIIISTIKKLLSNITNKNVKNQNLKMFWDVSYLSQAYLFYKLSQTKIINLSKLRPVFQYHGTSRFLKNEIQDYFVEVVGAHEILHSDLKQKKQKNLENSGMINPWKNWLRGHYNFDLYPIRWSKLLSQKWRNRVKQDRKNKDFNQCDSYEKKGLIDYKKQNPFETHYSLPTKKKKKYIYDSLSYKSINYEDNKDSYIYELPVQVKNNQESCYKYNKDKCKFFDILTDLPIDKYLVKNNYLVKANIRDLEKTMDRKYFDWRMLHFSIKNKGDIRVWRHNESDTNSKKNTQNGVKNFELIQKINKKIIKKIKKKELFYLTINQDKKSNPSNNKKQIFFDWMRMSEKKISRYRSNSNPKWFFPKFLILYNAYKIKPWMIPIKSLLFDLNENEIFSKKKLIEKKNGNKAKKESVAKEGVDSVLSNHTKNLQKDSAGADVKKGIKKKQSKKKIEGKLGVLRTGHFRFQLNWPNPEISKSLFMNLNGFSFMLRRLDLKKLSLAAIRNNEFSLEFLLPPSDDITFHELLEKGIFIIEPVRLSLKNDGKFIMSQTIGISLVQKNKYQLNQRYQEKGYPYKRSFAESIAIHQKRTENRTSNHYDLLVPENILSPRGRREFRILICFNSGNKNDIHRNTAFDDGNKVKTDDQVLDKRSKHLDRYQNQLKNLKLFLWPNYRLEDLACMNRYWFDTNNSSRFSMLRIHMYPQLKIR
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ATPAM_PHAVU
Sequence: MEFSSRAAELTTLLESRMTNFYTNFQVDEIGRVVSVGDGIARVYGLNEIQAGEMVEFASGVKGIALNLENENVGIVVFGSDTAIKEGDLVKRTGSIVDVPAGKAMLGRVVDALGVPIDGRGALSDHERRRVEVKAPGIIERKSVHEPMQTGLKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTILNQKQMNSRATSESETLYCVYVAIGQKRSTVAQLVQILSEANALEYSILVAATASDPAPLQFLAPYSGCAMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKRSDQTGAGSLTALPVIETQAGDVSAYIPTNVISITDGQICLETELFYRGIRPAINVGLSVSRVGSAAQLKAMKQACGSLKLELAQYREVAAFAQFGSDLDAATQALLNRGARLTEVLKQPQYAPLPIEKQILVIYAAVNGFCDRMPLDKIPQYERDILTTIKPELLQSLKGGLTSERKIELEKFLKEKAKNYTL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: EF1GA_XENLA
Sequence: MAGGTLYTYPDNWRAYKPLIAAQYSGFPIKVASSAPEFQFGVTNKTPEFLKKFPLGKVPAFEGKDGFCLFESSAIAHYVGNDELRGTTRLHQAQVIQWVSFSDSHIVPPASAWVFPTLGIMQYNKQATEQAKEGIKTVLGVLDSHLQTRTFLVGERITLADITVTCSLLWLYKQVLEPSFRQPFGNVTRWFVTCVNQPEFRAVLGEVKLCDKMAQFDAKKFAEMQPKKETPKKEKPAKEPKKEKEEKKKAAPTPAPAPEDDLDESEKALAAEPKSKDPYAHLPKSSFIMDEFKRKYSNEDTLTVALPYFWEHFDKEGWSIWYAEYKFPEELTQAFMSCNLITGMFQRLDKLRKTGFASVILFGTNNNSSISGVWVFRGQDLAFTLSEDWQIDYESYNWRKLDSGSEECKTLVKEYFAWEGEFKNVGKPFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma-A, EF-1-gamma-A, eEF-1B gamma-A, p47.