PharMolix/UniProtQA huggingface dataset:
Protein: PETL_MAIZE
Sequence: MLTITSYFGFLLAALTITPALFISLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AROA_ACET2
Sequence: MLLKVRKSKASGNVRIPGSKSHTIRALFFASLAEGKSEIQSPLISDDALSAVEVCRALGAKIEKEDDKYVVEGFGGNPEVPEDVINVGNSGTTLRFGIMTAALGDGCSVFTGDRQIRQRPLGPLLCAINNLGAEAFSTRNNGRAPVVVKGKLKGGRTEIDSVTSQYLSSILINSPLIPLDTEVIVTRLNEVPYVDMTLWWLDKLGIKYENHDYKTFYIKGGQRYRPLNVTIPGDFSSATFFAVQAAISGEEFVLDNLDMTDPQGDKMVFSILEDMGAKVKVEGKSVRIKGCELVGREIDMNAIPDALPAMAVAGCFAKGETKLLNVPQARIKETDRIHVMCEQLKKMGADITELEDGLVIRESRLKGCKLEGYGDHRVVMSLAIAGLNAEGETVIDTAEAVNVTFPDFVNFLSRCGADISTCE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_COXBU
Sequence: MNIVILGTQWGDEGKGKIVDMLTEDVAAVVRFQGGHNAGHTLIIDGEKTILRLIPSGILREGVLCLIGNGVVLSPPALMEEIEELNAKGIPVTEQLRISSACNLLLPYHVALDKAREAELGTKAIGTTGRGIGPAYEDKVARRGIRAMDLLHPDQLLEKIKKATAYHNIQLEHYYHQTPLDYQSIYNQLMEFREKIKPMIGDVSALLGNLRRQNKHIIFEGAQGSLLDIDLGTYPYVTSSNTTAGSAATGSGFGPLYFDRVLGITKAYVTRVGAGPFPTELTNEEGKKMAKRGNEFGSVTGRPRRCGWFDVISMRRTIQINSLTGIVLTKLDVLDEFAKIHLCTAYRCDGEVVNEPPFDQSLLESCEPVYEEMPGWQTSTYGLTDYSEMPKEARNYISRLEELLGVPITIISTGPDRKHTIVRQAVFNQVITAKG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_THEP1
Sequence: MKCPFCGSMDTRVLDSRPTLDGTAIRRRRECSSCGKRFTTYERYEEAPVLVVKKDGRREKFDREKIKNGMIKACEKRPVTYEQIEEAVNRICLKLREEGSFEVETKRIGELVMEELKKLDQVAYVRFASVYRDFREVDQFLEIVKELKREKEGEEQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ALXM_PHOS4
Sequence: MIKSNLVISSLAIVSSMSYAGVEFSNPSGQLGEPANYTQFANILSASELQISDPNGKKGNKEYFALDNDFTGIVNDNFYVDKQSQALVFKMANDHLRNELRVQKNFRTDLPDHFYTLYANVEILHPLQSMANSTSKQNEITFLQVHNKGLDDQGTHNVPHPLLRVVWKENNQGVKGHFWAITKNNAVICKGSFGKKNKDKEMCRADVAYSKIDLGPAPTDKGTDFTITVGNKTLAIDVNGQRKVEKNIDYWRHLLSYFKAGVYNQFTQGESEAHFNQLRYQVNTP
What are the official names of this protein?
Alginate lyase, Poly(Beta-D-mannuronate) lyase, Poly(mana) alginate lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 6 family.
Protein: RL34_ACIBY
Sequence: MKRTFQPSELKRKRVHGFRARMATKAGRQVLARRRAKGRHSLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SPAT1_HUMAN
Sequence: MKKDKKRNKIPIDNYPIQTLVNMSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVVNKFISAGFLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKLKSFAPPYALQPELYLLPVMDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNLN
What are the official names of this protein?
Spermatogenesis-associated protein 1, Sperm-specific protein SP-2.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: ATPG_MYCTO
Sequence: MAATLRELRGRIRSAGSIKKITKAQELIATSRIARAQARLESARPYAFEITRMLTTLAAEAALDHPLLVERPEPKRAGVLVVSSDRGLCGAYNANIFRRSEELFSLLREAGKQPVLYVVGRKAQNYYSFRNWNITESWMGFSEQPTYENAAEIASTLVDAFLLGTDNGEDQRSDSGEGVDELHIVYTEFKSMLSQSAEAHRIAPMVVEYVEEDIGPRTLYSFEPDATMLFESLLPRYLTTRVYAALLESAASELASRQRAMKSATDNADDLIKALTLMANRERQAQITQEISEIVGGANALAEAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MINE_ALKOO
Sequence: MDLWKFFSKESSTSKNVAKERLKLVLVHDRANCSPDFLEMVKGDIIKVISDYMEIDEDGLDIRLTKTKREYDDASIPALVANIPIKKMKDRGR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GNTDO_RALSP
Sequence: MLDEEERITMSHELGRLEDLPQDYRDELKQLNLVPLWPSLRAVLPPNVPTRQTQPTYWSYQTLKPLLLKAGELTPIEKAERRVLVLANPGHGLEKMQASAAIYLGMQLLLPGEWAPSHRHTPNAVRMIVEGEGAYTTVDGEKCPMSRGDLILTPTGLWHEHGHDGNEPVVWLDVLDLPLVYYMEASYHIDGERQQVDPGRGDCAWTRAGVVPTPVFQRSDKRYPLLRYPWADTRAALLSLAADQPEQECVQVTYVNPETGDDAENILGFYALMLKPGQTLRLPVRSPAVVFHQIEGRSEARIAESTFALREADTCCAPGYTEVTLKNLSADQPSFIFMADESPLHRKLGVFENRG
What is the function of this protein?
Catalyzes the oxygen-dependent ring fission of gentisate between the carboxyl and proximal hydroxyl groups at positions 1 and 2 of the aromatic ring to form maleylpyruvate.  Can also catalyze oxidation of alkyl- and halogenated gentisates.  Exhibits higher affinity for 3-substituted gentisates than for gentisate but has higher activity with gentisate.
What are the official names of this protein?
Gentisate 1,2-dioxygenase, GDO, Naphthalene degradation protein I.
What is the protein family that this protein belongs to?
Belongs to the gentisate 1,2-dioxygenase family.
Protein: HIS2_BACCR
Sequence: MENAFKLLYKTIEERKGSPLPESYTNYLFSKGEDKILKKIGEECAEVIIACKNNDKEEVVKEMVDVFYHCFVLLAEKNIALEDVMREVKERNGKLSRVGDRREIDTL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APBP2_MOUSE
Sequence: MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSSSPQSTEEVVQSFLMAQNVEGPSC
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(APPBP2) complex specifically recognizes proteins with a -Arg-Xaa-Xaa-Gly degron at the C-terminus, leading to their ubiquitination and degradation.  The CRL2(APPBP2) complex mediates ubiquitination and degradation of truncated SELENOV selenoproteins produced by failed UGA/Sec decoding, which end with a -Arg-Xaa-Xaa-Gly degron.  May play a role in intracellular protein transport: may be involved in the translocation of APP along microtubules toward the cell surface.
What are the official names of this protein?
Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Associated with membranes and microtubules.
Protein: NRDR_THISH
Sequence: MRCPFCGAPDTRVIDSRLAGEGDQVRRRRECLSCSERFTTYENAELNMPRVVKRDGSREPFNEDKLKSGMTHALEKRAVSTDKVEEAVARIKRKLLGQGEREVDSRRIGEWVMEELRNLDQVAYIRFASVYLSFADVQAFREVIERLEKDLTPEMRKHQIPLLGDEEGEGKD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FABA_SHEDO
Sequence: MEKANSFTKEQLIACGQGELLGANSPKLPIDNMLMVDRIVRINEDGGAFGKGEIIAELDINPTLWFFDCHFKGDPVMPGCLGLDAMWQLVGFYLGWEGAQGKGRALGVGEVKFTGQVLPDAKKVTYKLNIKRKIHRKLVMGIADATMEVDGREIYSATDLKVGIFSDTSTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_XANOM
Sequence: MARTTPIERYRNFGIMAHIDAGKTTTSERILFYTGVSHKIGEVHDGAAVMDWMEQEQERGITITSAATTAFWSGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYSVPRMAFVNKMDRTGANFDKVVEQLKARLGAYAVPMQVPIGAEDGFEGVVDLLKMKAIHWDTASQGTTFEYSDIPAELVDVATDARSFMVEAAAEASEDLMDKYLNEGDLSEEEILKGLRERTLKVEIVPVFCGSAFKNKGVQAMLDGVVHLLPSPADRPPVQGIDEDEKEDTRAATDTAPFSALAFKIMTDPFVGSLTFFRVYSGTLNSGDQVYNPVKSKKERVGRILQMHSNNREEIKEVRAGDIAAAVGLKDVTTGDTLCAQDKIITLERMVFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHAKQSGGKGQYGHVVIELSPMTEEDRKSDNVKDDFLFINDITGGIIPKEFIPSVEKGLRETITSGPIAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKASPVLLEPIMKVEIVSPEDYLGDVMGDVSRRRGVLQGQDDSPSGKIINAMIPLGEMFGYATSLRSMSQGRATFSMEFDHYEEAPANIADAVTKKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_ACAM1
Sequence: MLKFLNQVTSYGKESFQAARYIGQGLAVTFDHMKRRPITVQYPYEKLIPSERFRGRIHFEFDKCISCEVCVRVCPINLPVVDWEFNKEIKKKQLKHYSIDFGVCIFCANCVEYCPTNCLSVTEEYELSTFDRHELNFDNVAMGRLPYKVTQDPMVTPIREFAYLPESEMDGHNVDHTAPRAGQTPAEIVASTPKPETKEG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RUVB_BURL3
Sequence: MIETDKLATEQRIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRSEPLDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDFAEVKADGQITAAVADAALAMLDVDPVGFDLMDRKLLEAILYKFDGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSVPDTGRTERGEWDTPDGK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YVAR_VACCC
Sequence: MFVYKNNFRIQYDRRSFFKCFRYVFFEIIHFMREYWFHVSTKEGKLVIIFMNLYSFTIVFDFRKHS
What are the official names of this protein?
Uncharacterized 8.5 kDa protein.
Protein: HISX_ECOL6
Sequence: MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKTRGDEALREYSAKFDKTTVTALKVSADEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDADMARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSTLASTIETLAAAERLTAHKNAVTLRVNALKEQA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: MYG_PROGU
Sequence: MGLSDGEWQLVLNVWGKVEGDLSGHGQEVLIRLFKGHPETLEKFDKFKHLKAEDEMRASEELKKHGTTVLTALGGILKKKGQHAAELAPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LOR17_ARATH
Sequence: MFPFLKQRSRSVHGEDAPSSTESTVSVAAADIGGACTTLTVWRKSLLVSCEGFTVIDSNGDLIYRVDNYARTRPEELILMDKDGNSLLLMHRTKKITLVDSWGIYEANDTKGETKIPKCPTWYMRKNLKMNILSTKSDILAYVYSGSFDKKNSYIIKGSYRCKSCKIVHVPLNKTVVEIKRKEVRTKGVRFGSDVFDLVVNPGFDTGLAMALVLLLDQMFS
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 17.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: YNYF_SCHPO
Sequence: MKKRFDWCLILIDIIEKLLNEADLSILIIVIC
What are the official names of this protein?
Uncharacterized protein C1711.15c.
Protein: DAPA_LEPIN
Sequence: MIAKSGSNQESNPMFQGVYTAIITPFKNDKIDYDSYFKLLEKQIKAGVSGVVPCGTTGESPTLSHSEHAELIRETVKAVQGKIQVVAGTGSNSTKEAIELTEAACKDGVDGILSVNPYYNKPTQEGLFQHFKSIAEHSTVPVMLYNIPGRTSVNLLPETVLRLSEVKQIRSMKEATGDLGQMGKLISLVGNKMTVLSGDDNLTLPLLAIGGVGVVSVISNLFPKALVQLVESFQQGKISEAKKIHYDFIEVFALAFMETNPIPIKAAMCWFGHCGPEIRLPLTPLSQNETSSKFKKVLEGLKEKGYE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_YERP3
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGSELGLKAKEIMDAGKLVTDELVIALVKERITQEDCRDGFLLDGFPRTIPQADAMKEAGIKVDYVLEFDVPDELIVERIVGRRVHAASGRVYHVKFNPPKVEDKDDVTGEELTIRKDDQEATVRKRLIEYHQQTAPLVSYYHKEADAGNTQYFKLDGTRNVAEVSAELATILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISC2A_MOUSE
Sequence: MAAARASLGRILPESSILFLCDLQEKFRPSIAYFPQIVSVAARMLKVARLLDVPILLTEQYPEGLGPTVPELGAQGIRPVSKTCFSMVPALQKELDGRSQLQSVLLCGIETQACILNTALDLLHRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLATSESLILQLVRDASHPQFKEIQKIIKEPVPDSGLLSLFQGQSPLTSC
What are the official names of this protein?
Isochorismatase domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the nucleus in the presence of CDKN2A.
Protein: 1C03_GORGO
Sequence: MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEDGSHTLQSMYGCDLGPDGRLLRGYSQFAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQQRAYLEGLCVESLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLPEPLTLRWEPSSQPTIPIVGIVVGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Class I histocompatibility antigen, Gogo-C*0202 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AP3D1_MOUSE
Sequence: MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKGVPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPPSDSESEDEKPKAIFHEEEPRHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQKRYQDAPGVEHIPVVQIDLSVPLKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKEKGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAEAVKSPEKEGVLGVEKKSKKPKKKEKKTKEREREKKDKKGEDLDFWLSTTPPPAAAPIPAPSTEELAASTITSPKDECEVLKGEEEDHVDHDQERKSSRHKKKKHRKEKEKEERPRDKKKAKKKQVAPLENGAAAEEEEEPIPPMSSYCLLAESPYIKVTYDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTRPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISMSFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLAQC
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity).  Involved in process of CD8+ T-cell and NK cell degranulation (By similarity).  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (PubMed:21998198).
What are the official names of this protein?
AP-3 complex subunit delta-1, AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta-1, Delta-adaptin, mBLVR1.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYM_XANOR
Sequence: MTRTALVTTALPYANGPLHLGHLVGYIQADIWVRARRLRGDKTWFVCADDTHGTPIMLAAEKAGVTPEAFIASIQASHERDFAAFGVTFDHYDSTNSPVNRELTEAFYTKLEAAGHISRRSVAQFYDPAKGMFLPDRYIKGICPNCGSADQYGDNCEVCGATYAPTELKEPRSVISGATPELRDSEHFFFEVGQFDGFLHEWLAGDVALPGVKAKLKEWLDAEGGLRAWDISRDAPYFGFQMPGQPGKYFYVWLDAPIGYLCSFKTLCAQMGEDFAAHLVDGTQTELHHFIGKDIVNFHGLFWPAVLHGTGHRAPTRLHVNGYLTVDGAKMSKSRGTFVMARTFLDVGLEPEALRYYFAAKSSGGVDDLDLNLGDFIARVNADLVGKFVNLASRCAGFIGKRFDGKLAEALPDAAQYDRFVAALAPIREAYERNDAASAIRQTMALADEANKYIDDTKPWVIAKQDSADAQLQSVCTQGLNLFRVLVAALKPILPRTCAEAEAFLSAPMTSWEDVIRPLTSHTIQPYTALFTRIDPKLIDAMTDASKDTLAAPAAPATTSKAAPAKPDTKPAAAANPQSPISNPSFIGMDDFAKLDLRIGKVLVCECVEGSDKLLRFELDAGELGKRQIFSGIRASYGEPEALVGRSVVFIANLAPRKMRFGISDGMILSAGFDGGALALLDADSGAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REA1_ECOLI
Sequence: MANHETHSVIAGGIESDLHIDSSKYPHPFCSLLQKRAHFDSFKHLIFIRGLLVIAHGKRKNKISASMVSFYVSLVQVMCAHYIPDTNKVNL
What are the official names of this protein?
Putative defective replication initiation protein, RepFIC replication initiation protein.