PharMolix/UniProtQA huggingface dataset:
Protein: PREX1_MOUSE
Sequence: MEAPGSGGGDGGGDPGGDGAHPDARGPVSGPCAAARDSERQLRLRLCVLNEILGTERDYVGTLRFLQSAFLQRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKVPAVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHTAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTELLLQGNLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMSKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYAPVIKDRDYHLKTYKSVVPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLIPPQEDDYGFDLEEKNKAVVVKSVQRGSLAEMAGLQAGRKIYSINEDLVFLRPFSEVETILNQFFCSRRPLRLLVATKAKETIKVPDHPEALSFQIRGTAPPCVFAVGRGSEAVAAGLCAGQCILKVNGTSVANDGALEVLEHFQAFRNHREEALGLYQWVYHSHEDAQLARASQGAPDEDPQEDDQPDSALPLLSLGPQLSLHEDSAVVSLTLDNVHLEHGVVYEYMSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAVDDSIFVQNCGRLMAMSSAIVTMSHYEFHNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQASLEPHPLCGLDFCPTNCHVNLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGLNPMAYTQHCITTMAAPSWKCSPAVDEDSQGQGLNDSSYGSASGAPSQQDRGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSAAPAPCDPSLVEETSSSPPVSEESEVDRTDHSGIKKVCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSIHALLKGPVMSRAFEETRHFPMKHSWQEFKQKEECTVRGRNLIQISIQEDPWNLPSSIRTLVDNIQQYVEDGKNQLLLALLKCTDTELQLRRDAVFCQALVAAVCTFSEQLLAALDYRYNNNGEYEESSRDASRKWLEQVAATGVLLHWQSLLAPASVKEERTMLEDIWVTLSELDNVTFSFKQLDENSVANTNVFYHIEGSRQALKVVFYLDGFHFSRLPSRLEGGASLRLHTVLFTKALESVEGPPPPGNQAAEELQQEINAQSLEKVQQYYRKLRAFYLERSNLPTDAGATAVKIDQLIRPINALDELYRLMKTFVHPKAGAAGSLGAGLIPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLPKCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYQLCQPPVDGDL
What is the function of this protein?
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP.  Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein.  May function downstream of heterotrimeric G proteins in neutrophils (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,4,5)-dependent Rac exchanger 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane (By similarity).
Protein: HIS8_STRSV
Sequence: MVKLKGLRQINPYVAGQQPNERDMIKLNTNENAYGPSPKVAEALQNFDDQELRKYSSLDQTELCQALAANLGVSPDQLIIGNGSDDILSMAFLAFFNSGESVLFPDLTYGFYKVWADLYHVPFREIPLTDDFEVHPSDYFGDNGGIILANPNAPTGIYLPLEQLEEILASNQDVVVVVDEAYIHFGGQSALPLLETYPNLFITRTFSKDAALAGLRVGYGLGHPDLIAVMKAVKDSINPYSVDLLAESLALAAVQDWDYYLETGRAIQETRDWFAGELAALDFQVLTSQTNFVLAQPSGISAAELFQQLEERRIYVRYFPKAERIKDFLRISIGRREEMETVLAAIEEICSS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: Y4079_MYCPA
Sequence: MSTARSDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQLPPELIEAEPTIPLQQQAMVGYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPWPAGTTVYELDQPRVLEFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSVWSAEGLMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQALMARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTPSDELMAGYGRGRRRPRSATSCRGTCSSPRSGGRPEGLAFRQGESRARRHRRDVAGQHGFGNQCGGPDCGSAQHRRAQVDHPAQQRGFSDDAPDAAPAERGEPGERGGQVVRLVDARGQHRGVLEPLATALTQVRAHRMSRVADHHDGPARPGPGGGAVVKVVAQHLVAGRRCQHPRNRFGPIGESCLQIGQFAARRELPFRSALGGEPIQAIRTHRHMAGFDAGTKCLAGQLGVHRRSPHRAMRCSRRTGRRAGR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4079.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PA2HC_PSETE
Sequence: MHPAHLLVLLGVYVSLLGAARIPPLPLNLIQFSNMIKCTIPGSQPLLDYANYGCYCGPGNNGTPVDDVDRCCQAHDECYDEASNHGCYPELTLYDYYCDTGVPYCKARTQCQVFVCGCDLAVAKCLAGATYNDENKNINTGERCQ
What is the function of this protein?
Snake venom oligomeric phospholipase A2 that has potent presynaptic neurotoxicity.  Chain C is not itself neurotoxic, but it is essential for the neurotoxicity of textilotoxin.  Chain C possesses a very low phospholipase activity.
What are the official names of this protein?
Acidic phospholipase A2 homolog textilotoxin C chain, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_XANOR
Sequence: MITLGHLLGLGAVLFCISLAGIFLNRKNVIVLLMSIELMLLSVNVNFIAFSRELGDTAGQLFVFFILTVAAAEAAIGLAILVTLFRTRRTINVAEVDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TXCA_CAEEX
Sequence: MKHLSIFFVFFCCICVMLCDAYGDCKKNSDCKAGECCVNTPPFARSTCQKYLQQGEFCAHMGKYNPLGKYINMCPCGKGLKCQLKDVSGPLALFRSRMLTCV
What are the official names of this protein?
U3-aranetoxin-Ce1a, U3-AATX-Ce1a, Neurotoxic peptide caeron.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 20 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQCB_BACSU
Sequence: MITQLYRERTAADLKNRISKVLLNGNETEIVELTIQGAVVTVLTQREEDIKHIKSVQILDDQNNVITERTTDLDVSNNRTLDFRITFEVV
What are the official names of this protein?
Uncharacterized protein YqcB.
Protein: RT10_EMENI
Sequence: MSLFSPHRILLRTGSAFQLATATRALLSTSSQLRNTKNAQSGLAEQARAEEPVASSPSQTTRPEQKSLEEETTKQTQTHADSTVNEWGARLTDLNINARLPRSVQALYLRPLRRKAEYGLPVCDLQLRSYSVRNLEFFADFAIRAAYYLNLPVSGPVPLPKIVERWTFPRSSFVHKKSQENFERITVRRLIQIKDGNSQAVQAWLAFLRKHAFYGVGMKANIWEHESIEIAKTMDQTLPEIEKALEPHISQFGRREDAEPAHDLITNFLGSERLSLSKGPLTDVRGG
What is the function of this protein?
Involved in mitochondrial genome encoded proteins translation.  Involved in the binding of tRNA to the ribosomes (By similarity).
What are the official names of this protein?
37S ribosomal protein S10, mitochondrial, Mitochondrial ribosomal small subunit protein 10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PRP31_ARATH
Sequence: MATLEDSFLADLDELSDNEAELDENDGDVGKEEEDVDMDMADLETLNYDDLDNVSKLQKSQRYADIMHKVEEALGKDSDGAEKGTVLEDDPEYKLIVDCNQLSVDIENEIVIVHNFIKDKYKLKFQELESLVHHPIDYACVVKKIGNETDLALVDLADLLPSAIIMVVSVTALTTKGSALPEDVLQKVLEACDRALDLDSARKKVLEFVESKMGSIAPNLSAIVGSAVAAKLMGTAGGLSALAKMPACNVQVLGHKRKNLAGFSSATSQSRVGYLEQTEIYQSTPPGLQARAGRLVAAKSTLAARVDATRGDPLGISGKAFREEIRKKIEKWQEPPPARQPKPLPVPDSEPKKRRGGRRLRKMKERYQVTDMRKLANRMAFGTPEESSLGDGLGEGYGMLGQAGSNRLRVSSVPSKLKINAKVAKKLKERQYAGGATTSGLTSSLAFTPVQGIELCNPQQALGLGSGTQSTYFSESGTFSKLKKI
What is the function of this protein?
Involved in pre-mRNA splicing.  Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity).  Functions in association with STA1 and ZOP1 in spliceosome dynamics and pre-mRNA splicing.  Required for transcriptional regulation and pre-mRNA splicing of cold-responsive genes, such as LTI78/RD29A, KIN2/COR6. 6 or COR15A, especially under cold stress.  May play a role in stress response.  Involved in transcriptional gene silencing of endogenous transposable elements, independently of the RNA-directed DNA methylation (RdDM) pathway.  Seems not to participate in the small RNA biogenesis of the RdDM pathway (PubMed:25684655).
What are the official names of this protein?
U4/U6 small nuclear ribonucleoprotein Prp31 homolog, Pre-mRNA-processing factor 31 homolog, Protein EMBRYO DEFECTIVE 1220.
What is the protein family that this protein belongs to?
Belongs to the PRP31 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, Cajal body.
Protein: AT131_MOUSE
Sequence: MAVVGNAVPCGARPGGARDNGSPQPGSRLRPGLAAGPALIANGDELVAAVWPYRRLALLRRLTVLPFAGLLYPAWLGAAASGCWGWGSSWTQIPEAALLALATICLAHALTVLSGHWSVHAHCALTCTPEYDPNKVTFVKVVPTPNNGSTELVALHRDKGEDGLEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPVASDDIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADARLHVIFGGTKVVQHIPPQKATSGLKPVDNGCVAFVLRTGFNTSQGRLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWVEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPIETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREIKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIDKAHTLILHPPSEKGQPCEWRSIDSSIVLPLTLGSPKALALEHALCLTGDGLAHLQAVDPQQLLCLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSPVLSNSGPRVSRSTKQKSALLSPEEPPASHRDRLSQVLRDLEEESTPIVKLGDASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQGLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFSVHFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIGQVLALDFCLALLADRVLQFFLGTPKLRVPS
What is the function of this protein?
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum.  Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane.  Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.
What are the official names of this protein?
Endoplasmic reticulum transmembrane helix translocase, Endoplasmic reticulum P5A-ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYP_RHOP5
Sequence: MRLSRYFLPILKETPKEAEIVSHRLMLRAGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIADRHKRELLYGPTNEEMITEIFRAYVKSYKSLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDIDEAAARRAYNRMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEFIVLAETGESAVYCDSEVLNLPVPGEDVDYDGDLTPIIKQWTSVYAATEDVHEAERFDREVPAERKLHTRGIEVGQIFYFGTKYSEAMKALVAGPDGVEVPIHGGSYGVGVSRLLGAIIEACHDENGIKWPEAVAPFRAAILNLKQGAAETDAACEQLYRELIAKGVDVLYDDTDQRAGAKFATADLIGIPWQILVGPKGLADGTVELKRRADGSRENVALAEAVARLTQ
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CAMJ8
Sequence: MVDFRKFYKENANVAYTVLGYPNLQTSEAFLQRLDQSPIDILELGVAYSDPIADGEIIADAAKIALDQGVDIHSVFELLARIKTKKALVFMVYYNLIFSYGLEKFVKKAKSLGICALIVPELSFEESDDLIKECERYNIALITLVSVTTPKERVKKLVKHAKGFIYLLASIGITGTKSVEEAILQDKVKEIRSFTNLPIFVGFGIQNNQDVKRMRKVADGVIVGTSIVKCFKQGNLDIIMKDIEEIFKK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: COAD_VIBVU
Sequence: MSKKALSRVVYPGTFDPITNGHLDLIERAAKMFDEVIIAVAASPSKNTMFTLEERVDFARQVTRHLDNVTAQGFSGLMVDFARAVDANVLIRGLRTTVDFEYEFGLTNMYRRLLPGLESVFLTPSEEHAFISSTIVREVAIHGGDVTQFVPTVVAEALHQKKKV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_SHEPA
Sequence: MSKKYIIALDQGTTSSRAIVFDHDTKMVASSQREFSQMYPQPGWVEHDAMEIWASQSSTLIEVLARADIHSEDVAAIGITNQRETTVVWDKVTGKPVYNAIVWQCRRSKAICDELKAQGLEDYIKQTTGLVLDPYFSGTKIKWILDNVEGVRERAEKGELLFGTIDTWLVWKLTEGKVHVTDPTNASRTMLFNIHTQQWDDKLLDAFDIPRSILPEVKPSSAIYGYTRIAGEGSHIAIAGMAGDQQSALFGQLCIEEGMAKNTYGTGCFLLMNTGVEAVQSQHGLLTTIAIGADGGINYALEGSVFMGGATVQWLRDELGLIRDAQDTEYFAKKVEDTNGVYLIPAFVGLGAPYWDPDARGALVGLTRGANRNHIIRAALEAIAYQSRDLLDAMSKDSCVELKQIKVDGGAVANDFLMQFQADITNVEVLRPELTETTALGAAFLAGLAVGFWDSTDELKHKAGIERNFTPQISMQKRDSLYKGWQEAVTRTR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RS17_CAUVC
Sequence: MPKRILEGVVVSDKGDKTVVVKVERTIVHPVLKKIVRQSKKYHAHDEANAYKAGEAIRIIECAPKSKLKTWEVLPKASA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GID1C_ARATH
Sequence: MAGSEEVNLIESKTVVPLNTWVLISNFKLAYNLLRRPDGTFNRHLAEFLDRKVPANANPVNGVFSFDVIIDRQTNLLSRVYRPADAGTSPSITDLQNPVDGEIVPVIVFFHGGSFAHSSANSAIYDTLCRRLVGLCGAVVVSVNYRRAPENRYPCAYDDGWAVLKWVNSSSWLRSKKDSKVRIFLAGDSSGGNIVHNVAVRAVESRIDVLGNILLNPMFGGTERTESEKRLDGKYFVTVRDRDWYWRAFLPEGEDREHPACSPFGPRSKSLEGLSFPKSLVVVAGLDLIQDWQLKYAEGLKKAGQEVKLLYLEQATIGFYLLPNNNHFHTVMDEIAAFVNAECQ
What is the function of this protein?
Functions as soluble gibberellin (GA) receptor.  GA is an essential hormone that regulates growth and development in plants.  Binds with high affinity the biologically active gibberellin GA4, but has no affinity for the biologically inactive GAs.  In response to GA, interacts with specific DELLA proteins, known as repressors of GA-induced growth, and targets them for degradation via proteasome.  Seems to be required for GA signaling that controls root growth, seed germination and stem elongation.  Partially redundant with GID1A and GID1B.
What are the official names of this protein?
Gibberellin receptor GID1C, AtCXE19, Carboxylesterase 19, GID1-like protein 3, Protein GA INSENSITIVE DWARF 1C, AtGID1C.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGC_PSYCK
Sequence: MISAAIVGGTGYTGIELIRLLSAHPKVSIDLLTSRSEAGTRADEIFPSLRGISDIVFSDLGDETLATLQQCDVVFFATPHGVAMKQAEALTQAGVKVIDLAADFRLQSLSEFEHWYQQMHTCPDLLKTAVYGLPEVNRAKIAEALVVGNPGCYPTTAILGLKPIIEAQNKQSKQLIESRIVIDAKSGVSGAGRQASLALNYAESTDNFKAYSVEGHRHLPEIEQGVAQLLDSQFKHRIRFLPHLVPMIRGMLSSIHMELTDAGALVDWQQVFEQSYASEQFIDVMPKGLYPDTRSVRASNRLRIAVHQDNERAELTVIVVQDNLVKGAAGQAVQNMNVMFGLDESLGLNFAPIVP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I56A3
Sequence: MDSNTVSSFQDILTRMSKMQLRSSSEDLNGIITQFESLRFYRDSLGETVMRMGDFYSLQNKNKKWREQLGQKFEEIRWLIEEIRHKLKITENSFEQITFIQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YPQ2_YEAST
Sequence: MSCSNGIWPTVSNLCGSLSFFTSVISLFPQIIETYRDKSVDGLSPYFLLAWLCGDITSLIGAKLTGQLLFQILLAIYFLLNDSFVCGQYYYYGVLHENKLATVGHEPKPLLPELVENGELLREEEDMIQGGSSAESPRSSRRRSAITAALAIAHTISTASAYPLNVGSTQSQVGPPGDGKNSQLGTILSWIGASFYVGARIPQLIKNYNRKSTDGLSPFLFATTLLCNITYNLSIFTSCRFLDNQNKREFIVNELPFIFGSAGTIAFDLIYFYQYYILYATDMQLRELERELYSPEEDSAAQLVTERTSLLSGETQT
What is the function of this protein?
May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole.
What are the official names of this protein?
Probable vacuolar amino acid transporter YPQ2, PQ-loop repeat-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the laat-1 family.
Protein: RLME_DESAH
Sequence: MKNRGRTKPKKNQWADHYTQKARDENYPARSVYKLMEIQKRFQVIKKGASVLDLGCAPGSWLIHAAELTGPSGRAVGIDLKPVDAALPPNAIAHTGDIFEMESTLGEAVGQDYDAVISDMAPATTGRKDIDAARSFALCEAALRVACGLLADGGNFVCKIFQGAEFKQFENQVKSRFTSHKIFKPDSCRKSSKEIYIIGLGKK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRH1_DROME
Sequence: MTESKNDTKSWAPKQIWIKDVLKKSGTELLDISKSPAKAVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQFCLQVPPPLTATTTSVGLGVPPSGGQQEHFELLQTPQQRQMQLQLQDQHQQEQQQFVSYQLAIQQHQKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEVPDDEAEAAAASAAASTSAGSSAGSPSLQGVSSNSESSNHSPPSSPPATKKPRQARQPRVSKTVAATLSIPTSSPLSPSSLSSTYSPSASSMASPPPTSAHYLPVQMEADALSRDSGVSSAQPAHSTYADEEPTDLSMQQVQGQLPESTVDYYQAPPSLLELQPQPAGLTINPALLEAASIARRHDDNDDQVQDEDVHAAAWQMMQLCRGHGSLPPTEQPAPSHQPQVPTLHVSDLAANYDDTHEATVLIEHFKRGDLARHGLHKGYAPVPKYESALPNPDVVRRVEAAIGLRSSTESPERSSSPESDSLMMADRNVMTLPLRKRKHYMNKGDDGQVDSEKASGDGTSAAGGAASVGAGDGPGSKVMRMSSVIQFAKAS
What is the function of this protein?
Plays a general role in the hierarchies of gene expression leading to metamorphosis.
What are the official names of this protein?
Krueppel homolog 1, Krueppel homologous protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: SCX8_MESMA
Sequence: GRDAYIADSENCTYFCGSNPYCNDVCTENGAKSGYCQWAGRYGNACYCIDLPASERIKEPGKCG
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This acidic toxin has a weak toxicity and is active against mammals.
What are the official names of this protein?
Alpha-mammal toxin BmK-M8, BmK8, Bmk M8, BmK-VIII, BmKVIII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TBAL3_MOUSE
Sequence: MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFFHETRAGKHVPRTLFMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLAEQCSGLQGFLIYRSFGGGTGSGFTSLLMERLSVEYCKKIKLEFSVYPSPRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYDICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEEVGLSF
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain-like 3.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NOP10_IGNH4
Sequence: MKFLMKKCVRCGRYTFKDVCPVCNGQTTVPHPPRFSPEDKYVKYRVLAKLTKERPSSEGSTLSS
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: KEFG_SALSV
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.