PharMolix/UniProtQA huggingface dataset:
Protein: MNTH_BRADU
Sequence: MDARSPDLTTDAAGWRTDVPTTKSLAEVNASVALPTAGVWWRRLLAFVGPGYLVSVGYMDPGNWATDLAGGSKFGYTLLSVILLSNLMAILLQSLAARLGIVTDRDLAQACRATYSPAVNFLLWLACEAAIIACDLAEVIGTAIALKLLFGIPLIGGALIAALDAFLLLLLMNRGFRFLEAFVIALLAVIAVCFAVQIVAAAPPVAEVLHGFMPKSEIFTNPEMLYIAIGIIGATVMPHNLYLHSSIVQTRAYERNETGRREAIKWATTDSTIALMLALFINAAILVVAAATFHKSGHSDVAEIGQAFELLSPLLGLGIASTLFAIALLASGLNSTVTATLAGQIVMEGFLDLRLPSWARRLLTRGIAIIPVIIVTAIYGERGTADLLVFSQVVLSMQLPFAVIPLVRFVSDRRKMGKFAISPYVAAIAWIVAGVIVVLNLKLLADTLLG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F112_SSV1
Sequence: MAQTLNSYKMAEIMYKILEKKGELTLEDILAQFEISVPSAYNIQRALKAICERHPDECEVQYKNRKTTFKWIKQEQKEEQKQEQTQDNIAKIFDAQPANFEQTDQGFIKAKQ
What is the function of this protein?
Essential for virus function.
What are the official names of this protein?
Protein F-112.
Protein: R20K_CLOPA
Sequence: MERLVGKPAPEFEMKAVKGDGRGFTEVKLGDYKGKWLVMFFYPLDFTFVCPTEITGFSKRAEEFRDLKAELLAVSCDSQYSHETWINQDIKQGGLGKINFPIASDKTTEVSTKYGIQIEEEGISLRGLFIIDPEGIVRYSVVHDLNVGRSVDETLRVLKAFQTGGMCALDWHEGDDNL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Putative peroxiredoxin in rubredoxin operon, ORF C.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE1A_ORYSJ
Sequence: MCGIKQEMSGESSGSPCSSASAERQHQTVWTAPPKRPAGRTKFRETRHPVFRGVRRRGNAGRWVCEVRVPGRRGCRLWLGTFDTAEGAARAHDAAMLAINAGGGGGGGACCLNFADSAWLLAVPRSYRTLADVRHAVAEAVEDFFRRRLADDALSATSSSSTTPSTPRTDDDEESAATDGDESSSPASDLAFELDVLSDMGWDLYYASLAQGMLMEPPSAALGDDGDAILADVPLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription.  Confers resistance to high salt, cold and drought stress.
What are the official names of this protein?
Dehydration-responsive element-binding protein 1A, Protein DREB1A, Protein C-repeat-binding factor 3, rCBF3.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THOC5_SCHPO
Sequence: MTENAISDCLNVLDSTRTLCLRIHELKQHSRDADDQNPEQIKRQLMSKLLILREANRKSYEQLVQAKTITAEHKSELDNARIRLQALQYKKLHLKTIIKNYEEKEHIYTALPLVSKEEFLKEHPEFKSSNDHDLMLAILEDELKERQRLSTLKQELLKRKAALISENKAKRNALQKGDEKLQTFLRSSVPVQEYYNITSM
What is the function of this protein?
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export (By similarity).  The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription (By similarity).  THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase (By similarity).  The THO complex is also required to maintain TRAMP complex occupancy at sites of snoRNA transcription thus promoting exosome-mediated degradation of snoRNA precursors (PubMed:22965128).
What are the official names of this protein?
THO complex subunit tho5.
What is the protein family that this protein belongs to?
Belongs to the THOC5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DB129_GORGO
Sequence: MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSATISTMTPGQITYTATSTKSNTKESRDSATASSPPAPPPPNILPTPSLELEEAEEQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 129, Defensin, beta 129.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_SALA4
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWAPAPMPRQTDTRTVEASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTMVNLNLTQERYPDVQFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_HV193
Sequence: MEQAPEDQGPQREPYNEWTLDLLEELKNEAVRHFPRPWLHSLGQHIYNTYGDTWEGVEAIIRILQQLLFIHFRIGCRHSRIGITRQRRVRNGTSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: ODPB_CHAVU
Sequence: MSEKLLYEALNEGIHEEIERDPKVFVIGEDIGHYGGSYKVTKGLFEKYGNLRILDTPIAENSFTGIAIGAAMTGLRPIIEGMNMGFLLLAFNQIANNAGMLHYTSGGNFTTPLVVRGPGGVGRQLGAEHSQRLESYFQSVPGLQMVACSTPYNAKGLIKSAIRSQNPIIFFEHVLLYNIKENIPQKEYLVPLEKAELVRSGNQITILTYSRMRYHVLQAAKTLIEKGYDPEIIDIISLKPLDMGTISTSLRKTHKVLIVEECMKTGGIGTTLKSAILESLFDFLDTPIMSLSSQDVPTPYNGFLEDLTVIQPSQIVEAAEKIILYS
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYMEC_MELDN
Sequence: GKPICGETCFKGKCYTPGCTCSYPVCKKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mden-C.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: DXS_MARMM
Sequence: MSMTPKTPILDTVNSPADLKNLPLDRLKSLADEVRAETIDAVSVTGGHLGAGLGVVELTTALHHVFDTPTDTLIWDVGHQCYPHKILTGRRDRIRTLRQPGGLSGFTKRSESEYDPFGAAHASTSISAALGFAVGRDLKDENRNVIAVIGDGSMSAGMAYEAMNNAGHIGGRLIVILNDNDMSIAPPVGAMSHYFARLVSSQRYRSIRKLGKGVAKALRVEEAARRAEEYMRGMAMGGTLFEEMGFRYVGPIDGHDLDQLVPVLRNVRDGDNGPVLIHVVTQKGKGYAPAEASDDKYHGVAKFNVITGEQQKSKAAAPSYTKVFAQQLIREAEADSRVVGVTAAMPGGTGLDLFGERFPDRMFDVGIAEQHAVTFAAGLAADGMKPFAAIYSTFLQRGYDQVVHDVAIQKLPVRFAIDRAGLVGADGATHAGSFDIGYLGALPGMVLMAAADELELSRMVKTAALIDDGPSAFRYPRGNGTGIEIPDQIEPLEIGKGRIVREGSRIAILSLGTRLEESLKAADALAAQGFSTTVADARFAKPLDEDLILRLAREHEVLITVEEGAVGGFGAFVLHMLADKGALDRGLRIRTLTLPDVFQDQEAPFDMYETAGLNARHIAAKALEAMGKDDAAAERVAAALIAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RBFA_LEGPL
Sequence: MNNNFKRTDRIAEMIQRKLALIIPQEIKDPRLKGFVTISAVKVAADLGHAKIYFTVLNEDKSVVTNILNGAASYLRSALARSITLRTVPQLHFIYDESIEYGQRLSRLIDEVNPPDSSSDDNN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIHD2_BOVIN
Sequence: MESSSKGLLTQVTQFWNLLDDLAESNPESYQKFIQQQLKEGKELCAAPEPQLCLQTRILKPKEKLLFINLCQWKRIPAPESATHPVPLSIGRPEDISETSDVYTVIDVAYHPDVLQAAEKDQVKKDQLIRMAMRCIEEQFQFTLSNCYYVTKFRIKGSIQRMKQNLMGIQTNPADLREKMRNELTLEKIRSSTVSNSDQFPQLLLPEDQVSSKTACLIEEISSTEIKVEMKRPAYELKIVADQNEKPLKIELKVELPGVNSVSLCDLSVSEDDILIEVSEKYRLYLNLPESVDTEMTTAKFIKEKATLIVTMPLV
What are the official names of this protein?
PIH1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family.
Protein: RPOZ_NAUPA
Sequence: MRIEQINARALEKVNYDRYLLSQAIAKRVNELINGAKPLIELPKPNMQLTEIATLEIAEGLVKVKEV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: UPPP_STRT2
Sequence: MEIIMQTAQYIIELLKAVFLGIVEGITEWLPISSTGHLILVNEFLNLRQSKDFIDMFNIVIQLGAILAVMVIYFKRLNPFQPGKTAREVQLTWKLWLKVVIACIPSAFFGLLLDDWMEAHLSNFFVVAIMLVVYGIAFIWIEDRNRRVDPKVTDLARMSYKTAFYIGLFQVLSIIPGTSRSGATILGGIIVGTSRSVAADFTFFLGIPTMFGYSGLKAVKYFIDGNTLTGGQAAILLVASVTAFLVSLFVIRFLMNYIKKHDFTVFGKYRIVLGIIVLFYGAVKLIFG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1754_COXBU
Sequence: MVDDEKREVSEEIEEALKKLHLDDVDWARALSPHEILYLLDRCPFLQIVSTNEIEAFSETKFITAQSGWTIHHYGEAMSSSPGPLLFQGGDYRILGDDDEGDDGEGGTIVNPGKGTIVKQAFTTAAEMIALAQKSGWRGVRIIDGHPLMQWAAWMQATDDAFHLEGYEPDEKARKKRERVKRSEVEDQLKINVKPTRR
What are the official names of this protein?
Uncharacterized protein CBU_1754.
Protein: DHMA_CAUVC
Sequence: MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: OSTC_XENTR
Sequence: MESLYRVPFTVLECPNLKLKKPSWLHMPSAMTVYAMVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG
What is the function of this protein?
Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Oligosaccharyltransferase complex subunit ostc.
What is the protein family that this protein belongs to?
Belongs to the OSTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPAT_SYNS3
Sequence: MVKVNGNYLKLKAGYLFPEIGRRVKAFSSANPEAQLIRLGIGDVTEPLPQACRDAMKSAIDEMGTAEGFHGYGPEQGYAWLREAIARDDFQARGCEISAEEIFVSDGSKCDSSNILDILGSGNRIAVTDPVYPVYVDSNVMAGRTGESGDDGRYGGLTYLPISADNGFAAQIPSEPVDLIYLCYPNNPTGAVATKAQLKKWVDYARANKALILFDAAYEAFIQDPELPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCALTVVPKGLKGKADDGSEVELWGLWNRRQSTKFNGVSYIIQRGAEAVYSDAGKQEVKALVSFYMENAAIIRRELSAAGIEVHGGQHAPYVWLKTPSGMDSWSFFDHLLQKANVVGTPGSGFGAAGEGYFRLSAFNSRSNVDEAMARIRNL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: NUSB_RHOP2
Sequence: MADSKKPAIKKPVPKGDRKANRRGAARLAAVQALYQMDIGGAGINETFAEFESHWIGNEVEGDQYLPAEAAFFRDVVSGVVRDQKKLDPLIDDALAKGWPLARIDAILRAVMRAGAYELEHRKDIPARVVVSEYVDVAHAFVEKDETGMVNAVLDQIARQFREDEFTRG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: APT_THESQ
Sequence: MDLKRFIRDIPDFPQKGIVFRDITPLLRNQEAFKEAIDRMCELVFDKEFDLVVAPEARGFILGAAMAYKLGKGFVPVRKPGKLPYKTVYEEYQLEYGTEQLHIHEDAIEKGQKVLIVDDVLATGGTAEALIRLVKKLGGEVVSLAFLVELSYLEPRKRLEGYDVKTLIVY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNU_SHIDS
Sequence: MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
What is the function of this protein?
Modifies the set of genes regulated by H-NS; Hha and cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA.  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC.
What are the official names of this protein?
OriC-binding nucleoid-associated protein, H-NS/StpA-binding protein 2, Transcription modulator YdgT.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: MYG_ORCOR
Sequence: MGLSDGEWQLVLNVWGKVEADLAGHGQDILIRLFKGHPETLEKFDKFKHLKTEADMKASEDLKKHGNTVLTALGAILKKKGHHDAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPAEFGADAQGAMNKALELFRKDIAAKYKELGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ENLYS_BPPS3
Sequence: MAMSPAVRNSVIAAISGGAIAIASVLITGPGGNDGLEGVRYKPYKDVVGVLTVCYGHTGKDIMPGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGGIYSFVYNVGAGNFETSTLLRKINQVDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
What is the function of this protein?
Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles.  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm where it breaks down the peptidoglycan layer.
What are the official names of this protein?
SAR-endolysin, Endolysin, Gene product 19, gp19, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Secreted as a signal-anchored, membrane-tethered, inactive endolysin which is subsequently refolded, activated and released by membrane depolarization driven by the pinholin.
Protein: HIS1_YERPP
Sequence: MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERL_BPP22
Sequence: MELDAILDNLSDEEQIELLELLEEEENYRNTHLLYEFAPYSKQREFIDAGHDYPERCFMAGNQLGKSFTGAAEVAFHLTGRYPGTKGYPADGKYGGEWKGKRFYEPVVFWIGGETNETVTKTTQRILCGRIEENDEPGYGSIPKEDIISWKKSPFFPNLVDHLLVKHHTADGVEDGISICYFKPYSQGRARWQGDTIHGVWFDEEPPYSIYGEGLTRTNKYGQFSILTFTPLMGMSDVVTKFLKNPSKSQKVVNMTIYDAEHYTDEQKEQIIASYPEHEREARARGIPTMGSGRIFQIPEETIKCQPFECPDHFYVIDAQDFGWNHPQAHIQLWWDKDADVFYLARVWKKSENTAVQAWGAVKSWANKIPVAWPHDGHQHEKGGGEQLKTQYADAGFSMLPDHATFPDGGNSVESGISELRDLMLEGRFKVFNTCEPFFEEFRLYHRDENGKIVKTNDDVLDATRYGYMMRRFARMMRDIRKPKEKKIPAPIRPVRRGR
What is the function of this protein?
The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction.  The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities (Probable).  Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine (PubMed:22771211).  Once the capsid is packaged with the DNA (headful packaging), the terminase cleaves the viral genome concatemer and is substituted by the tail (Probable).
What are the official names of this protein?
Terminase, large subunit, DNA-packaging protein gp2.
What is the protein family that this protein belongs to?
Belongs to the Lederbergvirus large terminase family.
Protein: NDUS3_PARTE
Sequence: MSLNQIQRACFCSGGVKKKKKPKYRFGFPMALYFFFEKLNFSYWTSTTVNPNHYVCVLPSEAGQALASVLGGELFLAKSQLVEATAFDLTGQGAEAGDLLVFLRNNGVVLSYSFYFFLLKKRITFFLHGGDKVSSLESFYSNANWLEREISEMFRGSNLLKKESRNLLLDYGSSFNPFLKKFPSTGHAEVVFNSFLKTTAYVQTAGVEL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase subunit 9, Protein P1.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: OTC_NEIMF
Sequence: MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKGKNIALIFEKTSTRTRCAFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDGIEYRGFAQETVEELTKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTEEVFESPASIVFDQAENRMHTIKAVMVAALGD
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGJ_ECOLI
Sequence: MSRRYSSATITLVILFCRRPHCRKISVRQYYQKRVIFYPTTLQRTACKKCLFLMRDIIISS
What are the official names of this protein?
Uncharacterized protein YmgJ.
Protein: DNAA2_CHLMU
Sequence: MLTCNDCSTWEQFVNYIKTRCSKTAFENWIAPIQVLEESREKIRLEIPNIFVQSYLLDNYKKDLCSFVPLDAEGNPALEFVVSEIKRSSPQIAASVTKPAVEVSEENKDFQLKLNGAYRFDNFIEGPSNQFVKSAALGIAARPGRSYNPLFIHGGVGLGKTHLLHAVGHYVREHHKNLRIHCITTEAFINDLVHHLRVKSIDKMKNFYRSLDLLLVDDIQFLQNRQNFEEEFCNTFETLIHLSKQIVVTSDKPPGQLKLSERIIARMEWGLVAHVGVPDLETRVAILQHKAEQKGLNIPNEIAFYIADHVYGNVRQLEGAINKLTAYCLLFNKPLTETTVRDTLKELFRTPSKQKVSVESILKSVATVFQVKIQDLKGTSRAKNVPLARQVAMYLAKTLITDSLVAIGAAFGKTHSTVLYACKTIEQKIEKDALLKNQISLCKNNIAIDSPQHFV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA 2.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.