PharMolix/UniProtQA huggingface dataset:
Protein: ATP5L_BOVIN
Sequence: MAEFVRNLAEKAPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPTAIQSLKKIINSAKTGSFKQLTVKEALLNGLVATEVWMWFYVGEIIGKRGIIGYDV
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit g, mitochondrial, ATPase subunit g, ATP synthase membrane subunit g.
What is the protein family that this protein belongs to?
Belongs to the ATPase g subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: ATPD_LEPBL
Sequence: MNDSGVSKIYASALLGAVNSPEEVEQELGDLVQLLFKEEKIRNFFLSPTVSIEEKENILEKNLRGKILDVTLNFLGVLLNKGRFINLPEIQKRFTVELDKKKGRVRAQIKSYPSLEPAQITKLGSILSEKFKSEFILEVSEDKTLLGGFVVQFNDLKIEKSIASQLGEIKKAMLEKKLPVGAVYEN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOD2_NITHX
Sequence: MTEALGTETPGMRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEQKTYLQAIPYFDRLDYVAPMNQEHAFCLAAEKLLGIAVPRRGQLIRVLYCEIGRILSHLLNVTTQALDVGALTPPLWGFEEREKLMMFYERASGSRMHAAYFRIGGVHQDLPPKLIDDIDAWCDPFLQVVADLDALLTDSRIFKQRNVDIGVVSLKQAWEWGFSGVMVRGSGAAWDLRKAQPYECYAEMDFDIPIGKNGDCYDRYLIRMEEMRQSARIMKQCIAKLRAADGQGPVAVEDNKIFPPRRAEMKRSMEALIHHFKLYTEGFRVPAGEVYAAVEAPKGEFGVFLVSDGSNKPYKCKIRAPGFAHLQAMDFICRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SMAGP_MOUSE
Sequence: MNNLPATPSPEELMTTPVFQAPETLSPQAEEASTALIAVVITVVFLTLLSVVTLIFFHLYKNKGSYVTYEPAEGEPSAILQMETDSAKGREKEEYFI
What is the function of this protein?
May play a role in epithelial cell-cell contacts.  May play a role in tumor invasiveness and metastasis formation (By similarity).
What are the official names of this protein?
Small cell adhesion glycoprotein, Small transmembrane and glycosylated protein.
What is the protein family that this protein belongs to?
Belongs to the SMAGP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle membrane; Single-pass type III membrane protein. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.
Protein: SDS23_DEBHA
Sequence: MSNSFSFQRQNPGSPLQQHSPIHNINTGGNSNSVSNQSNNHPQTPGHHVPSRKPSIVEMLSSPPPLPNTPDQEDIHSFSLSRNTSVSSRASSIYGNVNGGTSKGSIVGVDWAEIPLVELTESNKLVSINSGFSVQKAFETLMEHNLTSVPVSLSKTDSTDLTNCLTFDYSDVNTYLLLIMNKINLNDLSIYEGGDDVLSNQQKDSITKSINKAKKGEEVPVDFIVKLHPKNPFVKFSEQDTLYKAMESLGNGVHRVAITNMNGTKITGILSQRRLIKYMWENARRFPSLDFYINSTLQDLKIGSNNPITIYEDQLLIEALLKMFTERVTSLAVVDKTMALIGNISIVDVKNVTSSKNSHLLFKSVLGFIGYNLTQKGIEEGQDQFPIFHVNNQSSLGRVIAKLVATKSHRLWVVENRGSVHHGSVSSTSSSNSNSNSKSVTQSPKASPSTIESTLNQSVSTPSNVQNIPPGSEPGGLPGKLVGVVTLTDILGLFASSKSNKKIDPQFARNQRRRSSTSTTRSSFEGSSAGQDLFRKSYTTSAPAKTEGKR
What is the function of this protein?
Involved in DNA replication and cell separation.
What are the official names of this protein?
Protein SDS23.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSPQ_ECO45
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SOLM1
Sequence: MAAKESGEKLVALNKKARHLYEFLEKYEAGLVLMGSEVKSLRLGRISFKDGYVKFQDGEAFMIGVHIAPYENAGYAGHEPERPRKLLLHAAEINAMRVKVEQKGLTVVPVRVYFKNGRAKVEIALARGKKVFDRRDDLKSRDLDRDAARELARH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YDCC_BACSU
Sequence: MKKVRKSFVLLLTGLLAVLILSACGQKTQQDIVAGLDEKAKEYTSYKAKAKMTIETGSEPQVYNVEIWHKKPSLYRVYLENPKKDQNQVILRNENGVFVLTPSLNKSFRFQSDWPNNSSQVYLFESLVKDVQNDSDAVFTAKEKKYVFETKTNYQHNKMLPTQEITFNKKDMSPSSVKVMDTDRKVMVKVEFSSFEFNKQFDKESFDEKKNMTLSQMDVATSAKPSDTFAVKTPLELPLGVKLLEEKDISTEDGKRIIMTYGGEKSFTLIQEKAQIAKASSSVTLNGEPVNLGYTIGALSDASLSWTYDGVDYLLSSKDLSKEEMVTVAKSMQGQSSK
What is the function of this protein?
required for efficient sporulation.
What are the official names of this protein?
Sporulation protein YdcC.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HXD3_MOUSE
Sequence: MLFEQGQLTLELPECTMQKAAYYENPGLFGGYGYSKATDTYGYSTPHQPYPPPAAANSLDSDYPSSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGNQPPGLNSEQQPPQPPPPPPPTLPPSSPTNPGSGVPAKKTKGGLSASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAGQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYPAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVDSMAPTSGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D3, Homeobox protein Hox-4.1, Homeobox protein MH-19.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTCB_METKA
Sequence: MAPKSMLKHIRNNVVWELPEDYKGCMKVPGRIYATEKLIDGMEKGVFDQVANVACLPGIYGYSIALPDAHYGYGFPIGGVAAFDVEEGVVSPGGVGYDINCLAPGTKILTEHGCWVKVEDLPKMLTDQKLKVYDVDEGREDDSEIKFVMERGIEEDERAVVLVTESGLTIEGSEDHPVLTPEGYVELGEIEEGDLVVVYPFEGVEYEEKEGTILDESDFEDVDPQVLRYLEERDLIPLRWSDPKVGTLARILGFAMGDGHLGEQAGRLTLSFYGDERTLRELKRDLESLGVKANLHVRKRRYEIETASGRYEGEATSVELRVASRSFALLMEKLGMPRGRKVETPYKVPDWIKEAPLWVKRNFLAGLFAADGSVVKFKRYTPLPINLTQAKVEELEENLREFMNDVAKLLREFGIETTLYEVKSKKNVVYKLAIVGEENIKRFLGKVGYEYDPEKKVEGLAAYAYLKLKERVKKDRKEAAETAAEVYEETGSITKAHEAVADVVNRRFVERVVYDGGISSVRVPEDFPTFERFKEERVLAGGFVIEEVVEVKGVEPEYDRFYDIGVCHGAHNFIADGVVVHNCGVRVMKTDLTEDDVRPKLRELLETIFRNVPAGLGSRHRRVRLSTQELRQVMLYGAEWAVEEGFGFDEDLDHIESRGNMTHAYETIGWEEYGPRDDVASKRAIERGRPQLGTLGSGNHFLEVQVVDEIYDKEAAEKMGIREEGQVTIMVHTGSRGFGHQVCSDHLRIMERSMRDVERRFGVRIPDRQLACAAMGTDEAKRYFNAMNAAANYAFANRQMISHWTRESFVEVFGDEYGDADDMGIEVIYDIAHNMAKIEKHPVDGEERWLVVHRKGATRAFSEEALKKHGEPVPFEGLPQPVLIPGDMGTGSYILIGTEKAMEETWGSTCHGAGRTMSRAAAKRKFWGEDVARELERQGILVKAASMPVVAEEAPPAYKDVDEVVRAVAEAGISDPVVRLRPIGVVKG
What is the function of this protein?
Essential for tRNA splicing and maturation.  Acts by directly joining spliced tRNA halves to mature-sized tRNAs.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: UBP1_BOVIN
Sequence: MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKTSEYKGSEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVEDLSTKVEEYQKEEMSDNNSMEMDNMRHSEDYKEKLSKGNGKRKSDAEFGNMKKKVKISKEHQSSEENQRQTRSKRKAAGDTLEISHKIIPKHISENESTRPSQRKSKVKINWLKSAAKQPSILSKFCSMGKIATNQGSKGHCKENEYDLEEDLGKYENDNTTNDCELESPGNNDMPVHVNEVKPINKGAEQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEENSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKVTDLNSLELDKENFVIDQTCEIGKPEPLNEEEVRGVVENYDNEEVSIRVSGNNQPSKVLNKKNVEAIGLLGGQKSKADYELYNKASNPDKVASTALPENRNSETNNTNGTDESDSNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL
What is the function of this protein?
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2.  Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA.  Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1253_YERP3
Sequence: MQWLADYWWIILILLVGMILNGIKELRRLDHKRFLDNKPELPPHRDNNAQWDDEDDWPDQNKKK
What are the official names of this protein?
UPF0370 protein YpsIP31758_1253.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PYRR_PSEA7
Sequence: MSLPNPAELLPRMASDLRAHLAERGIERPRYVGIHTGGIWVAEALLKALGNEEPLGTLDVSFYRDDFTRNGLHPQVRPSALPFEIDGQHLVLVDDVLMSGRTIRAALNELFDYGRPASVTLVCLLDLNARELPIRPDVVGQTLSLGRDERVKLVGPAPLALERKVLSPAS
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PDXH_RHOBA
Sequence: MSDFIPPAMDQMRKNYSLGGLHENDAKSDPLVQFQSWFEEALEDVPNWFEPNAMTLSTSDVSGDITSRIVLLKGVEEKKFLFYTNYDSTKGSQMRANPRVSLCLFWPHCQRQVRIQGTVDKVSREMSETYFHSRPRDSQLGAHVSQQSSVIDSREAMESSLAQLKARYPEGTQIPLPENWGGYAVTPMSFEFWQGRPSRLHDRLVYKRDDADSNDWVMQRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PDRP_ERYLH
Sequence: MKRIHLHLLSDSTGETLEMIAKAALAQFENADVVRHFWPMVRSRQHLERIVPELSNNPGLVLFTLVNAETRRALRDHCRRLSLPAVDALDEVTAALEVQLGQEAHGRPGRQHKMDEAYFKRVEAIQFTIAHDDGVGWENWEEADIVLAGVSRSSKTPTSIYLANRGYKVANIPLVMESPPPPALYELKNPMVVGLTTAPERLVQIRRNRLLTLNEQAETSYVEKDRVTEEVKFARRLFSDNNWPVIDVTRRSIEETAAAVIRLHNERHARVKPGEKPI
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: C5622_YERPE
Sequence: MGKTLMALITAALLSTSSLVMAASVADDMETIAEHYGKVLKADSTAVIKQDLQAMRVAAVDAQKGIPTKLKSKVEDSPEMKDFRHGMDVLIGEIDGALALADQGKLDEAKQAAQDFKDTRNTYHKKYR
What is the function of this protein?
Electron-transport protein of unknown function.
What are the official names of this protein?
Probable soluble cytochrome b562 2, Cytochrome b-562 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b562 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NARW_ECOLI
Sequence: MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTHNLLNAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRELPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGSSLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDVAPQYVDISAGGGK
What is the function of this protein?
Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2.
What are the official names of this protein?
Probable nitrate reductase molybdenum cofactor assembly chaperone NarW, Redox enzyme maturation protein NarW.
What is the protein family that this protein belongs to?
Belongs to the NarJ/NarW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP12B_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-PR1 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CFA52_CHLRE
Sequence: MAEPLVLNSVIGFGGAIENGLIAHPDGRTIIYPLGSTIVLRDRADPRSQEFLQGHSDKVSCLALSRSGRYLASGQITYMGFTADIIIWDLESKQLIHRMALHKVKVQALDFSCDERFLASLGGQDDNALVLWDVASGNAICGSPCNTNFTNCVKFFNNSPDKLITAGNFNMNVWTYDAGNNKLRPTDATLGTLKRVFKSVVVDANDEYAYCGTTTGDVLQIALERVLFKNTGPAKGNVQMGVTATCEVPTGDILVGGGDGSLQLLRKMPALAGTKVEGAITSIALADMNARGFTFFVGTAMCNIYKPATSRLKEELVQTAHNDKINGMAFPNEYSEVFATCGTGFIRLWHLTTCRELLRIAVPNLECFCIAFTTDGSAILSGWSDGKIRAFGPQSGKIIFTINDAHQKAVTAIASTADSSRILSGGEEGMVRVWRIGRTSQTLEASMKDHKGPVNCIRIKGSGDECVSASSDGSCILWDLHTFKRRTSLFANTFFKSVVYHPDESQLVTAGTDRKVTYWDAYDGNAIRIIDGSDLDEVNALAVDRDGEALVSGGGDKLVKLWGYDEGHCYFVGVAHSGAITAVGVTPDKQRIVSVGTEGGIFIWDYQRPQTLADI
What is the function of this protein?
May play a role in cell growth and/or survival.
What are the official names of this protein?
Cilia- and flagella-associated protein 52.
What is the protein family that this protein belongs to?
Belongs to the CFAP52 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum.
Protein: YSP2_YEAST
Sequence: MRDEATRKKRSFSDGHFFKKLKLMSRKKQPVMERSKTTRTRKESTNSAAKSSLSLRRANNGRKTIAKRRVLTDIGSTNEGVAGNSGSNSPAQYSHTPHFSDSIPPLPLELPDIVSIRSSRSHISNKSNKNKHGIDLTFIPRRSLQNSKAGLKKPNTSPQGYFNIPVTIDRASEKVKHTDTKNTFNSSSSENERPVLSILQKDDSQSSSHPAIDSMSAPNNINNNNDIENSSNSLFDTILSIAHSAISHVPKISALNTEIQREFSHSGESHTGSTRHPYFHIHHAQQQHPLSQQQGPLPVSENANQNPNDTVLIHSPSANTAHRSSSFLRHLDYLLSPTSGPASDKHTQVEEGDDEEELSPLSKAFLSPSTQLVPTNTSTTPLSGSLTPNNRNVNANSNSETENDNDRDDRSNVGKVKFQPLKVHEPAISTFGKGNLTLEAVAGSSDIDNTTIDLDENNTNNNPNASSTNLSHISKSNVNNNLGPKELNTSYRNSTYIDMARFENSQSNLSSHRARSKTLPANKALENAVGDEGNSKRNSRYSSYSNDMAFDDADERKFRSMSKKFLNRRSFSPSNLGNKVIPGINLRNSFNKNRNSSSDFFSTNQGQQMPRTSTAGSGNIHAIMGLDSGNDDFKLEGIEYASEKKNSEFHTLFKDCDINPNEKLIVDHSCALSRDILLQGRMYISDAHIGFFSNILGWVSTVFIPFKEIVQIEKKTTAGIFPNGIVIDTLHTKYIFASFMSRDATFDLITDVWNQIILGKKYRNGFGNNDDGTISDSSSAFFDDSDDNDDDGDLDDDDPDINSTDMTSSDDIDADVFNESNDLGKNQKSTNYLLGPNKHSPTTADFKPSNNDHLVIEANINAPLGKVVNLLYGEDVSYYERILKAQKNFEISPIPNNFLTKKIRDYAYTKPLSGSIGPSKTKCLITDTLEHYDLEDYVKVLSITKNPDVPSGNIFSVKTVFLFSWDKNNSTKLTVYNSVDWTGKSWIKSMIEKGTFDGVADTTKIMISEIKKILSDEDSNINSKHQASNNESEEEIINLPTIGPPVHDPTEPDFQKGKDDTVIDEKINIPVPLGTVFSLLYGDDTSYIKKIIENQNNFNVCDIPKFVNNAREITYTKKLNNSFGPKQTKCIVTETIEHMDLNSFFMVKQIVRSPDVPYGSSFSVHTRFFYSWGDHNTTNMKVVTNVVWTGKSMLKGTIEKGSIDGQRSSTKQLVDDLKKIISNASSTKKKSRRRGKTVNKRKSSPSTIKNEKNEENFEDTSTKNSFFSAFSMLQQVNITSVQGIMTIISFFICLIFFFRLLFHSKNTSNIQIITPGTILINGNEYNYVPNFKTLYHVYEDNIIKDARRKDSNKNNIVTDTEGLIWDWLIDRGNGTVQNSVLSNHIKESNNKKVKLVNGVSDHKIQQLVESIKITELQLQEMKELLAQTDNTSATNQLL
What is the function of this protein?
Involved in induction of programmed cell death in response to reactive oxygen species (ROS) (PubMed:16962064).  May be involved in sterol transfer between intracellular membranes (PubMed:26001273).
What are the official names of this protein?
Membrane-anchored lipid-binding protein YSP2, Lipid transfer at contact site protein 4, Lipid transfer protein anchored at membrane contact sites 3, Yeast suicide protein 2.
What is the protein family that this protein belongs to?
Belongs to the YSP2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes to puncta in the cell periphery representing cortical endoplasmic reticulum (cER)-plasma membrane (PM) membrane contact sites.
Protein: SELD_SHEPC
Sequence: MSDSPVTLPESIKLTEYSHGAGCGCKISPKVLSTILASQLPVFTDPNLLVGNQSRDDAAVYKLNDEIGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPIMAIAILGWPINKLPAEIAQQVVDGGRQACMEAGIMLAGGHSIDAPEPIFGLAVTGQIALSDLKQNDTAKKGDRLYLTKPIGIGILTTAQKQKKLHDEDSLIAVNAMCQLNTIGATIAKISGVNALTDVTGFGLAGHLLEMCQGANLTAKLKFDAVPLLPRALDYLALGCVPGGTHRNYDSYGEHLPELSEHQKAILCDPQTSGGLLVAVSAAAEAELIALLDANHITPICIGSLETPTTQANVVLC
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: UVRB_STRGC
Sequence: MINRITDNKFELISKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYSDSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGRVLGEVDHLAIFPATHFVTNEDHMEVAIAKIQAELEEQLAKFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIRGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYENEQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTMTQSMQRAIDETARRRAIQMAYNEEHGIVPQTIKKEIRDLISVTKTALPDKEETVEIESLNKQERKDMIKKLEGQMQEAAGLLDFELAAQIRDMILEIKAMD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLL_CHLRE
Sequence: MKLAVYGKGGIGKSTTSCNISIALRKRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLSSKDYHYEDIWPEDVIYGGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFFEYDVILFDVLGDVVCGGFAAPLNYADYCIIVTDNGFDALFAANRIAASVREKARTHPLRLAGLIGNRTSKRDLIDKYVEACPMPVLEVLPLIEEIRISRVKGKTLFEMSNKNNMTSAHMDGSKGDNSTVGVSETPSEDYICNFYLNIADQLLTEPEGVIPRELADKELFTLLSDFYLKI
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
What are the subcellular locations of this protein?
Plastid, chloroplast.