PharMolix/UniProtQA huggingface dataset:
Protein: MURD_NITEC
Sequence: MNYADKKILVLGMGKTGISMVKWLSRAGARVSVADTRTTPPNLELLSQIVPLETIFCGPFKAELFKDIDAIAISPGVAIAEPLVQAALQQGVSVIGDIELFAIALDQHAPPGTKILAITGSNGKTTVATMVGEMARNTGWDVEVAGNIGLAALDALMQRIDTGKWPHLWVLELSSFQLETTSSLRPNAAVVLNLSEDHLDRYRIIEEYAAAKARIFPDPHNSCVQVLNREDARVYAMAHENSKQLTFGLSAPAFDDEFGVLPSGSDLWLAQGTTRLMKVSELAVAGLHNAANALAALALCRAIDLPFEPLLHALHIFKGLPHRMQKIAEFNGVTFYDDSKSTNVGSAVAALNGFRKNVILIAGGDGKGQDFSPLEQPVSKHTRGVVLLGRDAEKISQAIQGCNVPVHRVATMDEAVRVSFLLAERGDSVLLSPACASLDMFNNYIHRAEVFTTAVQGIEHKFILTAQTCH
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENH_ECO57
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCLEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILSFWLVGYSLGGRVAMMAACQGLAGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRSEPLTAVFADWYQQPVFASLNDDQRRELVVLRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: G6PI_BRUME
Sequence: MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYTLGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT80_RAT
Sequence: MRLKISLLKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLGIKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGIPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHVVFAHVVEQRWEWKNFQVTLTKRRTMQVRNVLNDAVDLLEFRDRVIKASLNHAHLVVSTSLQCYVFSTKNWNTPLIFDLKEGTVSLILQAERHFLLVDGGGIYLHSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIKDKADEKIIFLFEASTGKPLGDGKLLSHKNEISEVALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEEQIIKLGTMVHTLAWCDTCNILCGLQDTRFTVWYYPNAVYVDRDILPKTLYERDASEYSKNPHIVSFVGNQVTVRRADGSLVHISISPYPAILHEYVSSSKWEDAVRLCRFVKEQSLWACLAAMAVANRDMVTAEIAYAAVGEIDKVRYINAMKDLPSRESKMAHILMFSGNIQEAETILLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLETFGKQETNKRYLQYAEGLQIDWEKIKAKIEMEITKERDRSSSGQSSKNTGLKP
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
What are the official names of this protein?
Intraflagellar transport protein 80 homolog, WD repeat-containing protein 56.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Basal body and ciliary axoneme.
Protein: RL2_METH1
Sequence: MAIKKFKAYTNGRRNMSSLDYQANLTGHAPEKSLLVALPTKAGRNNQGKITTRHQGGRLKRFYRIIDFKRQKDGIPATVKTIEYDPNRSANISLVVYRDGEKRYILSPKGIKIGQVILSGDNVDIQVGNHLPLANIPEGTFVHNIELQPRQGGIIARSAGSSAQILGKDESGRYVILRLKSGEVRKVLAINRATVGEVGNEEHSLVNIGKAGRNRLRGIRPTVRGSAMNPNDHPHGGGEGRQPIGRKSPMTPWGKRALGVKTRATKKASNQFIIRRRKETK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS6_MYCCT
Sequence: MIKKYEVMYILDQDLKDTKELVAKLDGILSEGGQILESNDLGLLDFTYEINHKKKGFYHIVIVQATTQAIKEFERIAKIDKNVVRTLVLNTQNIQNYEQSVVLSKTDMTKFEEEQREKKNFRKPFIKREEAATKENK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PYRH_LIGS1
Sequence: MSDIKYKRVLLKLSGEALAGDQGKGINPPEILKVAEEIKEVHDLGVQIAIVVGGGNMWRGEAGAEIGMERAQADYIGMLGTVMNALALQDSLESVGVPTRVQTAIEMRQVAEPYIRRKAIRHLEKGRIVIFAAGTGSPYFSTDTTAALRASELNAEVILMAKNGVDGIYNADPKVDPTAKKYTKLTHMDIINKGLRVMDTTASSLSMDNNIALVVFNMNNRGNIKKVVEGEEIGTTVEGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ACIBC
Sequence: MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVYTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIREGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLNAASFYQIVQAFAQSK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CHLTR
Sequence: MFVDQITLELRAGKGGNGVVAWRKEKYLPKGGPYGGNGGNGGSILIEAVTNMYSFEEYRNLRFLKADDGQAGASNNRTGRNGKDLVLKVPEGTLLRDAATGELIHDFTKDGERIVVCQGGRGGKGNVFFKTSTNRAPTKATPGKPGEIRLVELELKLIADIGLVGFPNAGKSTLFNTLARTEVKVGAYPFTTLHPSLGLVHQEGMLYQKPWIMADIPGIIEGASQNRGLGLDFLRHIERTRLLLFVIDISGIERHSPEQDLKILMGELLAYKEELKDKDMVIALNKIDQLLPDEREERVALLKQQFPDQEFILLSGLTGEGVDALYDLFKSKLSE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_GEOTN
Sequence: MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALYGFLTREERNLFAKLLQVSGIGPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTARQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKALGYAEREIEKIIPALREETMSTEQYVKRALAMLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CHEB2_SHESR
Sequence: MTIKVLVVDDSALIRNLLGKMIEADSELSLVGMAADAYMAKDMVNQHRPDVITLDIEMPKVDGLTFLDRLMKARPTAVVMISSLTEEGADATFNALALGAVDFIPKPKLDSPQDFNEYQDLILEKIKSAAHAKLKTQRAAPAVVVQPSHKPALSNRVINTQLVAIGASTGGTEAILSLLQQFPAVMPPIVITQHMPPGFTRTFAERLNKLTRLNVKQAEDGERLLPCYVYIAPGDQHLEVIKVGGSFKTRLTQGDKVSGHRPSVDVLFNSVAECAGANTTAAILTGMGKDGADGMALIDEQGGKTFAQGEQSCVVFGMPREAIKRGVIHHVVELPQLADKMLNYLASLKRD
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_HELPY
Sequence: MKVLLLEDVKNLGKAGEVCEVKDGYGNNFLIANQKAKLATNEVINKYKAEVKKKAEKEALEKAQKLQMVETLQTITLTIHKKVGANGSLFGAITKEEITERLKEQHASLNLDKKDIELKHPIKSTGIYEIEVKLGSGVVGVFKIDVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TTC24_MOUSE
Sequence: MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM
What are the official names of this protein?
Tetratricopeptide repeat protein 24, TPR repeat protein 24.
Protein: SRA17_CAEEL
Sequence: MNQTELLESLKCASEGMVKAMTSTTMKLNFVFIATVIFLSFYFAGLAIQALLRNNIFSNSTRHILIVCLLNSIVHQAVTLETRIHQVYRSFVYSSEPCRLLFHFTECEVELYFYYLTNYFSTYAVFSLTFDRLVSHYKPKYYFSHQYYVSNSLLIIQLLLSLSTYYVGLYGVPLVGYAPICYYTPRLAVNFSKINDFRTATMVFCIIVTIFIYYLSVKSEKQIHRTSYSPGERYIACENVATSQSVCILIVLQFACIMLSSFGVNYIRARESLMSEENFNKIAPFFPGVTYASLCLPLVIYFKTKLTIRNRKLRIGVMTSMYGDVGDHMNRLKKSWE
What are the official names of this protein?
Serpentine receptor class alpha-17, Protein sra-17.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLYA_BRADU
Sequence: MTSAKTASAPDSFFTASLDQADPEIAAAIKGELGRQRHEVELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGGCEWVDVAENLAIDRAKKLFGAGFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAAGGHLTHGSPVNMSGKWFKAAHYTVRREDQIIDMDAVQKQAEEIKPKLIVAGGSAYSRAWDFKRFREIADSVGAYLLVDMAHFAGLVAGGVHASPVPYAHVTTTTTHKSLRGPRGGLILSNDETLAKKLNSAIFPGLQGGPLMHVIAAKAVAFGEALRPDFKVYAKNVVENAKALAEAMKSHGFDIVSGGTDNHLMLVDLRPKGLKGNVSEKALVRAAITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQVGGMIAEVLNAIAQSDDGKAPLVEAAIKERVKALTDRFPIYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOKU_BACSU
Sequence: MKTCEWCGELEAVPGRNTVYWELPDGTRAIELTDTPAMVCSSCGMTYQEENTVKEIEDQLLLIQTKKLPESLTYQQLMETERILKRNYFDFS
What are the official names of this protein?
Uncharacterized protein YokU.
Protein: MSRA_MYCUA
Sequence: MTSPQKAILAGGCFWGMQDLIRKQPGVIATRVGYSGGDVANATYRNHGTHAEAVEIIFDPQATDYRTLLEFFFQIHDPTTPNRQGNDRGTSYRSAIYYLDDEQKRVALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQHYLQRYPSGYTCHFIRPGWKLPRRATAGQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TMC6_HUMAN
Sequence: MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKEREERSRVGTTEEAAAPPALLTDEQDA
What is the function of this protein?
Probable ion channel.
What are the official names of this protein?
Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MUKF_SALDC
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: Y084_SFAVA
Sequence: MIVADRLNTTTSMVWFPDYENGVGDNDAPRSGTHRAIDMYRYVRDLVSTTNQDGPRTLSEAVEPIRSWVDRDREVNLKFVEMCIIDAYTTDRRQVDDDIDAQTVVILDAILTQDGTGLDSNGAQYYRDVVRTFHDRHIEHAKAIAENKRLVPLYVAMYSNWSNTSAPTRATMDIEAIRGRYTVSVPESMERPMVILFNDLTISEDLVVFATHGELIKYDTRYPPSSDAALAAMSSRRARKGGERDKRISLYMVRRGIYSPGMNYDIAHVHQTPGVGYVITVISNNAPTVDVPRSLVTALGMGGDDDQVVVSDVGGGVTYTASFVLNDITFVTEYLQHYTLLKCTDKATCIFVDETHLMKYARDWRRYTIASPRFIYEYNNFTVKFSATVESTRRDVARVSPYCRIRIYDAPNTQIMYGMANDITAHMIEYKSRERSIASLYAENLHNDQLLRINVRIMRDSKRVKREPGYLARQHRQVRRKLQAQKTGTNADVRSLIGVNNYARQCARLPTAVFDVDDVPEAKEHITYQLPNDRGTLYVYCDHDDAPYPGVVTNRLAGNKTEYPTVPCCYRLRRNANGDPDEGRTQSFYNTQRILNTQAFGKCPANLESVLMCQRYMSRDEVDAAGMETYFPKQSVVGDATAVRGGVNAGPNAAIEAVMRAVHAIKGRDSDPRRLVITTDRLADERSEMVSLLTCASQELFDMSATERNAWLNDTVSYFDPLRLVKLLQFHFDVNVYVYVRGARVKPVKSVRTTENGGVMLRFFEEYEQAWTDNDDVLVVPHHYAGADYHDLKVHESSVVIYVHSGTEISNLTYPHVEYIIFKRHRLVVPMIGKIYQRLLPKSMRNVYSFVYFDVVEDEDERDSLTVDEANALRILFYLSSGKSVSTEWSGKVSTTLNAPTTQTIDGIGRMVGVGGRALESMYSTEPLPSLAVDNHDHSMYYFDDNVKRKRLMNPEHSAKCQYAWYLNKLARVLLHLTAYTILKKGTLMSDLFLVDDVRFNRLHDSINTLFETGVVDMDSYGNLLIAEEERVLAIPSTRHVAWCTMHR
What are the official names of this protein?
Putative structural protein ORF84.
What is the protein family that this protein belongs to?
Belongs to the ascovirus HvAV ORF146 family.
What are the subcellular locations of this protein?
Virion.
Protein: HLAC_HUMAN
Sequence: MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA
What is the function of this protein?
ALLELE C*15:02: Presents CMV epitope derived from UL83 CC (VVCAHELVC) to CD8-positive T cells, triggering T cell cytotoxic response.
What are the official names of this protein?
HLA class I histocompatibility antigen, C alpha chain, HLA-C, HLA-Cw, Human leukocyte antigen C.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RMAR_VANPO
Sequence: MVFYMYNMMMNLNLLKEMRTNNKLVLNKLVLKNLLYWINKDTFKENMKIYSNYNNNYMNTNLQNKNIKRINNKLYRYMPIQSEWSNKLITKLYITNIKNMNKLLFKNIINNNNNDNFNIINLFNNKYNNNNIMMNLLMFKYLTGWSTQLKGRYTNNMSRTNTTVNKSGTFNNKKYTFIKNNYKLNYISANHNISNLYNVNKNGKYNLKIKLNYI
What is the function of this protein?
Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
What are the official names of this protein?
Ribosomal protein VAR1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MSRB_ECO5E
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: THII_STRSV
Sequence: MQYSEIMVRYGELSTKGKNRMRFINKLKRNIQAVLSVYPKVHVKADRDRTHVYLHGTDYQPVAESLKQIFGIQNFSPSYKIEKSVPALIEAVQSIMKEVYQEGMTFKITSKRSDHSFELDSRELNQTLGDAVFEAIPNVQVKMKAPDIELRVEIREEAAYISYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIREERSAQVIINGESLGQVASQTIESMQAINAVTNTPVIRPVVTMDKLEIIDIAEKIDTFQISIQPFEDCCTIFAPDRPKTNPKIKNAEKYETYLDVEGLVERAVAGIMITEITPQAETDEVDELIEGLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_SHIDS
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLVAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDHATRKYDEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_CHLT2
Sequence: MADLIMGIDPGTLVCGYALIKVENRYHIHPHSFGKVKLSQKLALAHRYKQLFTEISTILQQESPKAVVLETQYVHKNPQSTIKLGMARGVLLLAASLQDVPVFEYAPNTAKKAAVGKGNASKKQVQLMVSKLLRVPDLLAEDNEDIADAFALAMCHAHLAPYQDLKKTLV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HCN3_HUMAN
Sequence: MEAEQRPAAGASEGATPGLEAVPPVAPPPATAASGPIPKSGPEPKRRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKRSEPSPGSSGGIMEQHLVQHDRDMARGVRGRAPSTGAQLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLVPVRAGPWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLSANM
What is the function of this protein?
Hyperpolarization-activated potassium channel.  May also facilitate the permeation of sodium ions.
What are the official names of this protein?
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel HCN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSW_SYNY3
Sequence: MLTINLPKTFKVKYLLIALALFYLILVLLLPAIAVFYEAFHKGVEPFIQAMGDRNFQSALQLTVVMALISVPLNTVFGLCAAWVLARNQFPGRALFLSVLDLPFSISPVVAGLMIVLLYGKNGWIGSWFASWDIQIIFSVPGMAIATIFVTLPFVAREVIPVLEELGPEQEEAARTLGAKDWQIFWRVTLPNIRWGLLYGVLLTNARAMGEFGAVAVVSGSILGKTSTLPIFVEQEYKNYQTEAAFGAAVVLALLAVVTLVLKEILEQRTGHHKAV
What is the function of this protein?
Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Sulfate transport system permease protein CysW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.