PharMolix/UniProtQA huggingface dataset:
Protein: MED18_PICST
Sequence: MVHQLSLVSSIAHGSYVQTVSTLQAFTGMLSPQPIATYTLLTKPHEVFKPKFEPGKVNQIEQYYMKCITTWSDGSEFDLASAVIKENGSSNVFSGRLFHAEDESVQRIWTLQISDIPIAGKNQACSAQTIYESTLIHTHTNVKSEENKIDAMDVDLEHKDKSDVKGDTKEKEEDKKEEDKKEEDKKEEDKKEEDKKEEDKKEEEKVEKKNDEVKHSEVNLEDGAETGSGHKDSFLQFLEDLGYETISQYWIKGIRFFHGDIVIEIFKVLVRDDEVTEPKEEGKIALKLLDESNTFQIRTYINIAKSTDIDLINQGTKELLRLQEFLKNLFKLEIPDRMFMDSRVQVRK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPMT_SHEFN
Sequence: MEPSFWHEKWQLQQIGFHQNQVNPFLVKYWSHIGLNENTEVFVPLCGKSLDMFYLAEQRHTVLGCELNTLAVEQFFTDNGLTYQVNHTDEHVVFSTDQVTLYQGDIFTLPKSATASISGFYDRAALIAWPEEMRQQYVKALAALIPANVSGLLITLDYLQETLKGPPFAVSPRWVESYLTPYFDVELLECVDVLADNPRFMNKHVPWLNEAVYKLTRKS
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA53_CHLRE
Sequence: MNKSRAPPDARIQKMRELEERLANLKADRKVEQKMVAVAEFEARTTKKIVGNLVQQRYDALKARAEADLNARRQRLADKLDAEDLAMRQELLASKKTPEQRRAELAERARALAATREAERQALASTLYEKAFIQSCDVLRDENSKRILYRTIEERNAQIEHKMAQRIMEAEEKRMWHEMSEVERQKMEQRYLDDKRRDREKREEVLRILDEQVRQVNARRAEASMLRRAEIAELNATWRQMAADQEAADVQERENMKKLAAELQEFNRIKQMEISEAERSERELDLKILQEALSKEAADEAAELAFRERRREEMRRYREQLALMMEKEREETAERDALILKAQLEQEAKRDAELAARDEARRQLMAQVDAIRQIQIQEKLAKRLERAEEKAFERAQMAEEVAKAESDAAAKDAADRKAGIQRRLELQTMMVAKAHMKAAELDEKLAEGEATKRVEDQFKAKVNQTLSSTDPPVWHGRRKFDW
What is the function of this protein?
May play a role in filopodium movement.
What are the official names of this protein?
Cilia- and flagella-associated protein 53.
What is the protein family that this protein belongs to?
Belongs to the CFAP53 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: END8_SALPK
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQIITRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MIAB_HYDS0
Sequence: MKYFIKTYGCQMNINDSEKIKGILQTQGYEPATREEDADLVILNTCTIREKPDQKVWSHLGEIKKLKSINPNIKIGVCGCMAQRAGYEIASKMPFIDLVFGTKNIHHMPKLLEDVKVGNRAIEILEEEDPSENILDSYPTVRDNSYCAYVTIMRGCDKECTYCVVPFTRGKERSRNPQSILDEVKSLVDSGVMEIHLIGQNVTAYGKDIDYPFYKLLENISKIEGVKRIRFTTGHPIDMTDDIIETMANLPNMVNHLHLPFQAGSDRILELMKRNYTKAYYLNRIEKLKAKIKDITFSTDIIIGFPTETEEDFQHTLDVVQTVEFEQVFSFKYSKRPNTPAYYMEDDLTDEIKTDRIKRLLEIQKAITSKLMQRYKNTVQKVLVEDKKGNTYIGRTTTNVWCNITSSQDILGKEVEVLIAKAGFQSLDGVVQNIL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_SALPB
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDKLAQQLAIPASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVASDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYALWFEEVAARTGRLIAEWQTVGFAHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNALLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDRYRARLRTEAVDDALRQQQMQRVNPAVVLRNWLAQRAIDAAEQGDMAELHRLHEVLRQPFTDRDDDYASRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: MGTA_THEMA
Sequence: MIGYQIYVRSFRDGNLDGVGDFRGLKNAVSYLKELGIDFVWLMPVFSSISFHGYDVVDFYSFKAEYGSEREFKEMIEAFHDSGIKVVLDLPIHHTGFLHTWFQKALKGDPHYRDYYVWANKETDLDERREWDGEKIWHPLEDGRFYRGLFGPFSPDLNYDNPQVFDEMKRLVLHLLDMGVDGFRFDAAKHMRDTIEQNVRFWKYFLSDLKGIFLAEIWAEARMVDEHGRIFGYMLNFDTSHCIKEAVWKENTRVLIESIERAVIGKDYLPVNFTSNHDMSRLASFEGGFSKEKIKLSISILFTLPGVPLVFYGDELGMKGVYQKPNTEVVLDPFPWNESMCVEGQTFWKWPAYNGPFSGISVEYQKRDPDSILSHTLGWTRFRKENQWIDRAKLEFLCKEDKFLVYRLYDDQHSLKVFHNLSGEEVVFEGVKMKPYKTEVV
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEEX_ECO5E
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGEMKNGEAK
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: RL6_KLEP7
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLALGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NFIB_CHICK
Sequence: MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEFREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQPGSPSHNDPAKNPPVYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGELPSQPYYHDMNSGINLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTMKKPEKPLFSPTSPQDSSPRLSTFPQHHHPGIPGVAQSVISTRTPPSPSPLPFPAQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQPNSSGQVVGKVPGHFTPVLAPSPHHSAVRPVTLTMTDTKPITTSTEAYTASGTSQANRYVGLSPRDPSFLHQQQLRICDWTMNQNGRHLYPSASEDTLGITWQSPGTWASLVPFQVSNRTPILPTNVPNYGLNIIGEPFLQAESSN
What is the function of this protein?
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2.  These proteins are individually capable of activating transcription and replication.
What are the official names of this protein?
Nuclear factor 1 B-type, NF1-B, Nuclear factor 1/B, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/B, NF-I/B, NFI-B, TGGCA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CTF/NF-I family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TP1_LIMKU
Sequence: MFTMKKSLLLLFFLGAINLPLCQEERNAEEERRDGDDEGSVEVQKRFFPLLFGALSSMMPKLFGK
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria S. aureus ATCC 2592 (MIC=2. 5 uM), S. aureus ATCC 43300 (MIC=2. 5 uM) and B. subtilis (MIC=15. 0 uM), against Gram-negative bacteria E. coli ML-35P (MIC=30. 0 uM), P. aeruginosa PA01 (MIC=2. 5 uM) and P. aeruginosa ATCC 27853 (MIC=2. 5 uM) and against fungus C. albicans ATCC 2002 (MIC=5. 0 uM).
What are the official names of this protein?
Temporin-LK1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TCMO_PEA
Sequence: MDLLLLEKTLLALFLAAITAITISKLRGKPFKLPPGPFPVPVFGNWLQVGDDLNHRNLTDLAKRFAEILLLRMEQRNLVVISSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDIVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRFGWESEAASVVDDVKKNSKASVNGIVIRRRLQLMMYNIMYRIMFDRRFESEEDPLFVKLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKVCKEVKDRRLQLFKDYFVDERKKLGSTKSTYNEGLKCAIDHILDAQKKGEINDDNVLYIVENINVAAIETTLWSIEWGIAELVNHQEIQNKLREEMDKVLGPGHQVTEPDLEKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPALWKKPEEFRPERFLEEEAHVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVAKPRAF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THSA_BACDA
Sequence: MKIVLEEIAMATDKEVLIKEFLKALHEDNAAIFAGAGLSAASGFVNWKGLLKEAADELELDIEKETDLISLAQYFFNKNGRQRLSQLVIDNFSAEAQLNENHRILAQLPIDTYWTTNYDRLIEKSLTDVGKNPDVKIKQSDFALLKPKRDAIVYKMHGDIERASETVLIKDEYEMFHENNQLFSIGLKGDLISKTFLFIGYSFEDPDLEYILSRIRVLMGQDGRNHYCFFRKVNRNQYNHLPKEEGDEKFRYDSIKQELKCADLERYHIKPVLVDKYEDITEILQTILQRYCRSKILISGSAVEYKQFVPDHNTAQMFIHTLSREMVKAGFKIASGFGLGVGSAVINGSLDYVYSTNKRKISDYLILRPFPQYATNGLELMDLWDQYRRDFISDVGCAVFIFGNKEVNGKVVDAGGVRKEFDIAVAQGIKVIPVGATGYMSKTLWEETITNYDKYYSDFPALKADFEFIGDASHNHHEIITRIIKIITALRAGR
What is the function of this protein?
Probable NAD(+) hydrolyzing component (NADase) of the Thoeris antiviral defense system, composed of ThsA, TIR1 (thsB1) and TIR2 (thsB2) (PubMed:34853457).  Activated by a signal molecule generated by endogenous TIR1, TIR2 or ThsB from B. cereus.  After activation it binds and hydrolyzes NAD(+), leading to cell death and inhibition of phage replication (Probable).  Expression of Thoeris in B. subtilis (strain BEST7003) confers resistance to phages phi29, phi3T, SPBeta, SBSphi11, SBSphi13, SBSphiJ, SPO1 and SPR but not SBSphiC.  The TIR paralogs confer overlapping resistance to different phages (PubMed:34853457).
What are the official names of this protein?
NAD(+) hydrolase ThsA, NADase ThsA, Thoeris protein ThsA.
What is the protein family that this protein belongs to?
Belongs to the soluble Thoeris ThsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_ECOSM
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGAMSLADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPAEFCRMLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH2_PAEDU
Sequence: MAKKIKQIAIYGKGGIGKSTTTSNISAALSVAGYKVMQFGCDPKSDSTNTLRGGEYIPTVLDTLRDKQIVRAHDVIFEGFNGIYCVEAGGPAPGVGCAGRGIITSVSLLKQQKVFEELDLDYVIYDVLGDVVCGGFAVPVREGIAEHVFTVTSADFMALYAANNLFKGIHKYSTEGGALLGGVIANSINAPYAKEIVDDFVARTHTQVMEYVPRSVSVTQAELQGKTTIEADPNSKQAQIYKSLAQKIVDHTESKVPVPLETSELREWASNWGKQLVELEAGVLSPAAAGNL
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 2, Nitrogenase Fe protein 2, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: NUSB_ARTS2
Sequence: MSARGKARNRALDVLFEAEQRSLSAFDVLRSRREKTDQIVNPYTLEIVEGVVSHQAAIDEFLETYSQGWTLERMPSVDRIILRIGTWELLYNDDVPDGVAVSEAVALAKTLSTDESPSFINGLLGRLQQLKPSLLA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CLPP_PSEF5
Sequence: MFRNSYIQQNSDIQAAGGLVPMVVEQSARGERAYDIYSRLLKERVIFLVGPVEDYMANLICAQLLFLEAENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPNVSTTCIGQACSMGAFLLTAGAPGKRFCLPNSRVMIHQPLGGFQGQASDIEIHAKEILFIRERLNTLMAKHSGRTLEEIERDTNRDNFMSAEAAREYGLIDEVINQRPA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB_TRIVU
Sequence: MKFLLLTVGLTSICAIQAIENIHSKEELVVEKLIGPWYRVEEAKAMEFSIPLFDMNIKEVNRTPEGNLELIVLEQTDSCVEKKFLLKKTEKPAEFEIYIPSESASYTLSVMETDYDNYILGCLENVNYREKMACAHYERRIEENKGMEEFKKIVRTLTIPYTMIEAQTREMCRV
What is the function of this protein?
Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
What are the official names of this protein?
Beta-lactoglobulin, Beta-LG.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FKBP2_GIBZE
Sequence: MKAALFLSALASTAVGVVAEELKIDVTLPVICERKTQKGDGVHMHYRGTLKDSGKQFDASYDRGTPLSFKVGAGQVIKGWDEGLLDMCIGEKRVLTIPPEFGYGQRAIGPIPAGSTLVFETELVGIDGVPKPEKIETKVVEGAESAAEAISEATEAAATASQKVAGKVAEAIVDAAKAAKTIIADTDDAPEHEEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 2, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: MVP_RMV
Sequence: MSYEPKVSDFLALTKKEEILPKALTRLKTVSISTKDVISVKESESLCDIDLLVNVPLDKYRYVGVLGVAFTGEWLVPDFVKGGVTVSVIDKRLENSRESMIGTYRAAAKDRRFQFKLVPNYFVSTADAKRKPWQVHVRIQNLKIEAGWQPLALEVVSVAMVTNNVVVKGLREKVIAVNDPNVEGFEGVVDDFVDSVAAFKAIDSFRKKKKKIGGRDVNNNKYRYRPERYAGPDSLQYKEENGLQHHELESVPVFRSDVGRAHSDA
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma.
Protein: NADD_METEP
Sequence: MRIGLYGGSFNPAHAGHLHVSRTALRRLRLDRVWWLVTPGNPLKDHGVLAPLDERVAQARALATDPRIAVTGFEGGIGSRYTADTLRWLVRRQPALHFVWIMGADSLGTFHRWRRFDEILSLMPVAVIDRPGYTLTAPSARAAQAFASARIQEADAPTLAIRPTPAWTFLHGPRSALSSTALRTR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MUTL_LIGS1
Sequence: MAKIHELSEILANQIAAGEVVERPASVVKELVENSIDAGAKQIDIIIEDAGLKSIQIIDDGNGIEAEDVETAFKRHATSKIIDRKDLFKVHTLGFRGEALPSIASVSDVVMETAVSGRAGTKIHIKGGEVLEKTLSASREGTTITVSDLFYNTPARLKYLKSVQTELSYISDIVNRLALSHTDVALSLTNNGRQLLQSAGNGNLQQTIGAIYGVQNARQMIKFEDANLDFKISGYTSLPKLTRASRNYISLLVNGRYVKNFQLTKAVIEGYGSKLMTGRYPITVLSIELDPTLVDVNVHPTKQEIKISKEDELVTFIQKTIFERIGQENLIPDGLQNIKSKTKEKLDFEQLKVGLNEASKQYQTKQHRTGITSEVTAALFGEKLTKDESQTQTNEKIKEETKVELSPIIIKDKQDLKSDRVKEWDEKYQSRNKETEVTSIAEKNGSVDDKRKDTPRFPTLRYIGQMHGTFLFAEGEEGLYIVDQHAAQERVKYEYYREEIGKVSPTQQNLLVPIVLTYPTTDALIIDENIDKLKELGIYLEDFGQNTYIIRQHPTWFKEGQEESIIREMIDYFLKDRKLSIAKFREKTAIMMSCKRSIKANHHLDDKQAKSILEQLKTCENPFNCPHGRPVLVKLSNKDLEHMFKRIQDPHHTGILEED
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: BUT77_GIBZE
Sequence: MAYEIIDNIAAEGAPYYTPAQDPPAGTQTSGSTKVFTPITIRGVTFPNRLFLAPLCQYSAKDGYATDWHLTHLGGIIQRGPGLSMVEATAVQNHGRITPQDVGLWEDGQIEPLKRITTFAHSQSQKIGIQLSHAGRKASCVSPWLSINAVAAKEVGGWPDNIVAPSAIAQEAGVNPVPKAFTKEDIEELKNDFLAAAKRAIRAGFDVIEIHAAHGYLLHQFLSPVSNQRTDEYGGSFENRIRVVLEIIDLIRGEIPETTPILVRVSATDWFEYDAQFKDEFPESWTVEQTCKLAQILPKHGVDLVDVSSGGIHPKSAIAIKAGPAYQVDLAKQVKKAVGDSVLVSAVGGIKTGHLAEEVLQSGIDVVRAGRWFQQNPGLVRAFANELGVEVKMANQIDWSFKGRGKNGHKKSP
What is the function of this protein?
NADH:flavin oxidoreductase; part of the gene cluster that mediates the biosynthesis of butenolide, a mycotoxin that shows antibiotic activity but does not seem to play a major role in the spread of head blight in wheat (PubMed:17175185).  Butenolide is derived from glutamic acid via a 4-acetamido-2-butenoic acid intermediate (Probable).  The predicted function of the NADH:flavin oxidoreductase FG08077, the cytochrome P450 monooxygenase FG08079, the decarboxylase FG08083, and the putative acetyltransferase FG08082 are consistent with this pathway, however, the respective activities of the butelonide biosynthesis cluster enzymes have still to be experimentally determined (Probable).
What are the official names of this protein?
NADH:flavin oxidoreductase FG08077, Butenolide biosynthesis cluster protein FG08077.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: TYB_APLCA
Sequence: MSDKHDKPDISEVTKFDKSKLKKTETHEKNPLPTKETIDQEKQG
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).  May be involved in the regulation of structural plasticity in the CNS.
What are the official names of this protein?
Thymosin beta, Beta-thymosin.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PHR2_CANAL
Sequence: MLLKSLFPSILAATSFVSSVAAEDLPAIEIVGNKFFYSNNGSQFYIKGIAYQQNNLDSNESFVDPLANPEHCKRDIPYLEAVDTNVIRVYALDTSQDHTECMQMLQDAGIYVIADLSQPDESINRDDPSWDLDLFERYTSVVDLFHNYTNILGFFAGNEVTNKKSNTDASAFVKAAIRDTKAYIKSKGYRSIPVGYSANDDSAIRVSLADYFACGDEDEAADFFGINMYEWCGDSSYKASGYESATNDYKNLGIPIFFSEYGCNEVRPRKFTEVATLFGDQMTPVWSGGIVYMYFEEENNYGLVSIKDNTVSTLKDYSYYSSEIKDIHPSSAKASAESASSISRTTCPTNTNNWEASTNLPPTPDKEVCECMSASLKCVVDDKVDSDDYSDLFSYICAKIDCDGINANGTTGEYGAYSPCHSKDKLSFVMNLYYEQNKESKSACDFGGSASLQSAKTASSCSAYLSSAGSSGLGTVSGTVRTDTSQSTSDSGSGSSSSSSSSSSSSSSGSSGSKSAASIVSVNLLTKIATIGISIVVGFGLITM
What is the function of this protein?
Required for apical cell growth and plays an essential role in morphogenesis.  May be integral to the pathogenic ability of the organism (By similarity).
What are the official names of this protein?
pH-responsive protein 2, pH-regulated protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 72 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: AROD_STRPF
Sequence: MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAVAPAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKSVFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRIIEVLEMDISN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.