PharMolix/UniProtQA huggingface dataset:
Protein: MVP_BYDV1
Sequence: MAQGEQGALAQFGEWLWSNPIEPDQNDELVDAQEEEGQILYLDQQAGLRYSYSQSTTLRPTPQGQSSSVPTFRNAQRFQVEYSSPTTFTRSQTSRLSLSHTRPPLQSAQCLLNSTLGAHNQPWVATLTHSPSQNQQPKPSPPNRLTGRNSGRVR
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity).
What are the official names of this protein?
Movement protein, MP, 17 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the luteoviruses movement protein family.
Protein: PANC_THIDA
Sequence: MQVVHTVADLRAALSEADRSAFVPTMGNLHAGHVSLVELAKRHGGPVVASIFVNPLQFGAGEDFERYPRTLAADCDKLAEAGCDLVFAPDTSALYPVAQTFRVDVPAALAEDLCGAFRPGHFAGVATVVLKLFNLVRPQVAVFGRKDYQQLLVVREMVRQFNLPIDIVAGATLRDPDGLAMSSRNGYLSAAERAQAPQLQRELAAIVAAIDGGARNFAALAAAARQRLTGAGWRVDYVEIRDAESLKTATQETEALVVLAAAWLGQTRLIDNLEVTSAAGIAA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_CITK8
Sequence: MHPRFQTAFGQLADNLQSALAPILADEHFPAMLTAEQVSTLKRESGLDEDALAFALLPLAAACARTDLSHFNVGAIARGISGTWYFGGNMEFLGATMQQTVHAEQSAIGHAWLRGEKGLAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGRVPHTLRDYLPDAFGPKDLEIKTLLMDEQDHGFALEGDALTQAAIAAANKCHMPYSYSPSGVALECKDGRIFTGSYAENAAFNPTLPPLQGALNLLNLNGYDYPDIQRAILAEKADAPLIQWDATAATLKALGCNNIDRVLLG
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: TRUB_PSEA7
Sequence: MAQVKRIRRSISGILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDADKGYETVMRMGITTTTGDAEGEMLAEREVTVGRDDLEQALPRFRGDIEQVPPMYSALKKDGQPLYKLARAGEVVEREARSVTITRLDLLSFEPPCATLAVSCSKGTYVRTLVEDLGQVLGCGAHVAALRRTQAGPFVLAQAITLETLERVHAEGGPEALDQFLMPEDSGLLHWPVLQLSEHSAYYWLHGQPVRAPEAPKFGWLRVQDHTGRFIGIGEVTDDGRIAPRRLIRS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ISPH_EHRRG
Sequence: MHNAIYTGLQKEVEVILATPRGFCAGVSRAIEIVKLAIEYYKDTKTIYVLHEIVHNKYIVETLKTMGVIFIDKVDQAQDGSVLIYSAHGVSKSIKQLAELRDLEVIDATCPLVNKVHKEVQLYDKSGYQVILIGHKGHREVEGTVGQISTPVIIVQNLNDIDKIEIFDPDKLAYVTQTTLSVDDTKVIIDKLKKKFPNIKGPDLKDICYATQNRQTTTKRLAELVDIVFILGSKNSSNSNRLKELAAIQTQAFLIDSYKEIDLNLLNDITKIGITAGASAPDILVQQVIDFLKQHMKVKLSDLEIVQESVTFNVPRQLRQYKEQYNPI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NTE1_ASPNC
Sequence: MATGDGIIAAPPSLESSSLDPLHVLPASSSTAARSLATSIPALTASFSVVSGFSSHLPPPPVTPPAPSTMVGWIGWIFSFIFQVIPSVLYWIVTFTTITLPTWLFTLFSMSLTFTMNFTTLLLIALAVVSTISWFIRYRFLNMYSRLPPEPQRKEPQLDLFPDVPDSDTKPGLANYLDEFLSAIKVFGYLERPVFHELTRTMQTRKLIAGETLLLEEEKGFCLVVDGLVQIFVKSMRDRKSGSDEELNRMAGESSDEDDHRPDGRQGYQLLTEVKNGASMSSLFSILSLFTEDVQLRYADSSASSASSIGPGLAIGPDSFPASPREMDDSPHVYQGDRLDPASHRNSTAEDLPAVPPLNLGESQVPPAHSARSESRKYSGKTRRKSVHPDIVARAMVDTTIAIIPASAFRRLTRVYPKATAHIVQVILTRLQRVTFATAHSYLGLNNEVLGIEKQMTKFTTYDLPNELRGSALDRLKDKFIKERDRLGQEEVTKGIALHNPYGGRRPRSSSFRRKEAALQAKMVASKRPVSMVAQDSALSDRENSGVSPGDLLSTIQLSRFGPRYEHLAPRLLSPLTEKEHSPLRSPSPMIPGRASPFHRKESLDEDALFRESILECIMKGIGLTGSTNDFLRKSSHPSGDVSPKLLSYDSRRQKAVFSNNAFGFIDPYEGSADGESESMMSMSVTSAGGTSPIVNLREELRNDIEIVYFPQGSVLVEQGERHPGLYYVVDGFLDVGIPVDDKEEDLVGSSRPAHEELFPMLRRTNTSSSRVSGSAAAANDPRRKKQSRRSLYLIKPGGIQGYVGAVASYRSYTDVVAKTDVYVGFLPRASLERIAERYPLALLTLAKRLTSLLPRLLLHIDFALEWVQVSAGQVIYHQGDESDAIYLALNGRLRSVHEGPNGKMTVVGEYGQGESVGELEVMTESTRPATLHAIRDTELAKFPRTLFNSLAQEHPGITIQVSKLIAQRMRDLVETPLAEKGGEPGVSGTVKTAKSTLNLRTVGILPVTAGVPVVEFGNRLLQALHQIGVTNGATSLNQAAILNHLGRHAFSKMGKLKLSQYLADLEEKYGMVLYIADTSVNSPWTQTCITQADCILLVGLAESTPSIGEYERFLLGMKTTARKELVLLHGERYCPPGLTRQWLKNRVWINGGHHHVQMAFRLTAEPSHPQTKRFGTVLKQRVQVIQAEIQKYTSRRIRQSPLYSAQTPFKGDFHRLARRLCGRSVGLVLGGGGARGIAQVGVIKALEEAGIPIDVIGGTSIGSFIGALYARDADVVPMYGRAKKFAGRMGSIWRFALDLTYPTVSYTTGHEFNRGIFKTFGDSQIEDFWLEFYCNTTNISRSRAEYHSSGYTWRYVRASMSLAGLIPPICDEGSMLLDGGYIDNLTVDHMKGLGADVIFAVDVGSIDDNTPQVYGDSLSGFWAVVNRWNPFSSCPNPPTLSEIQARLAYVSSIENLERAKNTPGCLYMRPPIDPYGTLDFAKFDEIYQLGYAYGKNYLEKLKREGSLPLPEETEEKKKLQRTLAPRRASI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase nte1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RDGC_SHEPW
Sequence: MWFKNLTVYRFNKPFSVDTESMEKSLEDFTFSPCSSQDISKFGFSNAFGKHGDTLVHTAADRHLICATKEEKILPAQVIKEALEEKVALLESEDGRKLAKKEKDALKDEITTTLLPRAFSRRSQIRALILPEIQMILVDSSSAAKSEELMALLRKAIGTLPIIPMSFKTPIETQLTEWLKESKTPAPFEMQDEAELKSDSDEGGIVRFKQQDLSENEVLAHIEVGKQVHKLALHFGQSVAFLLQSDAAIKRLKFSEEFRAGNDDLGNEDPMARLDADFALMGSELIALVNAVVEALGGLEDSI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: XPO2_PONAB
Sequence: MELSDANLQTPTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTETKLVLDAFALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYIMIFRNQVPKEHLLVSIPLLINHLQAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLAVSKNPSKPHFNHYMSEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSNTIASAAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQNSKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQPKMFGMVLEKIIIPEIQKVSGNVEKKICAVGITKLLTECPPMMDTEYTKLWTPLLQSLIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAASVTLL
What is the function of this protein?
Export receptor for importin-alpha.  Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm.  In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor.  CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Exportin-2, Exp2, Chromosome segregation 1-like protein, Importin-alpha re-exporter.
What is the protein family that this protein belongs to?
Belongs to the XPO2/CSE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: HOGA1_XENTR
Sequence: MFGRTLFPARVIALGSGLFRTPLRTLAAGPALSIGGIYPPIATPFTDKEEVDYGKLHENLQNYSSFPFRGFVVQGSNGEYAYLTREERLEVVRRVRQAVPKEKLIMAGSGCESTQATIEMTVEMAQSGADAVLVVTPSYYRGKMTSSALVHHYTKVADHSPVPVVLYSVPANTGLDLPVDAVVTLSQHPNIIGLKDSGGDITRIGLIIHKTKHLGFQVLSGSAGFLLAGYSVGAVGGVCALANVLGAQVCELERLCLNGRWQEAKELQYRLIEPNTAVTRKFGIPGLKQAMEWFGFNGGKCRSPLLPLTEQEIKELRHIFTVNGWLSL
What is the function of this protein?
Catalyzes the final step in the metabolic pathway of hydroxyproline.
What are the official names of this protein?
4-hydroxy-2-oxoglutarate aldolase, mitochondrial, Dihydrodipicolinate synthase-like, DHDPS-like protein, Probable 2-keto-4-hydroxyglutarate aldolase, Probable KHG-aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YARCA_STRPY
Sequence: MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGSKYLEDGEYCQSLVKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNNEPKD
What are the official names of this protein?
Uncharacterized acetyltransferase in arcA 3'region.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: MRAY_PSEPK
Sequence: MLLLLAEYLQQFHKGFAVFQYLSLRGILGVLTALSLALWLGPWMIRTLQIRQIGQAVRNDGPQSHLSKSGTPTMGGALILSAIAVSTLLWADLSNRYVWVVLIVTLAFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLAAAVFLYKTAPTSVETTLILPFIKDVTIPLGVGFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGSGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGIFVVETLSVVIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDTC_YERPS
Sequence: MKFFALFIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATPLERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSRPTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVRVELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIVHYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPALRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPMVAALRGVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMCAWLLRSHPKGQQQRIRGFGKVLLAIQQGYGRSLNWALGHTRWVMVVLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIRVGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSIPLSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRLRNRFSKQPLMKLE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD_AZOVI
Sequence: MKDRLFLLGQHLLPHHLLSRAAGRLAECRVPWVKNSLIKAFARHFQVD
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.
Protein: TPIS_BORBU
Sequence: MRKTFLAGNWKMHYTSAEASIVAKKIATEVKTLKDDVVIMITPPFTALSKVSECIKGSNILLGAQNMSYMESGARTSEISPSMLLEFGVEYVILGHSECRLYLAETDEIINKKILAGLKHPFKYLILCVGETLDERDSGKTLEVVLNQVKKGLNCVSESDIQRIILAYEPVWAIGTGKTATKEEAEEVHKAIRLEITKLYSKSASDNIIIQYGGSVNSNNVKELMNEPNIDGALIGGASLKAESFLSIINNVL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_NITHX
Sequence: MEWTDDGIVLGVRRHGESSAIVELLTRGHGRHLGLVRGGAGSRMRPLLQPGNSVSALWRARLDEHLGAYALEGTRMRAANLLGASHATYGVTHLASLARLLPERDPHDGIFERLERTLDDFDTAGEAAIHLIRFELAMLTELGFGLDLSTCVATGTTTELIYVSPKSGGAVSRQAGEPWRDRLLRLPPFLREADEEQSGWSDQDLLDGFELTGRFLLRHVLEPRGQGHSDARAGFINAVVKHQARASAAAISG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: DDL_ANASK
Sequence: MSTWTGKRVAVLYGGRSSEREVSLRTGAACADALRQKGHDVVLLDVDLEVAARLRAERVEVAFVALHGRFGEDGSIQGLLESMAIPYTGSGVLASAMGMDKTVSKAIFRSLGLAVADYRVFPRASAGSIGVGDLPFGLPCVVKPAGEGSSVGVHLVNEAAELGPACRDAASHAGDVIVERYVKGTEVDVAVLDGKALGAIEIVPANAFYDYAAKYTAGTTKYFYPARLPEAHVRAVMEAAEAAHRGIGCSGVTRVDFIVAGDGTPYILEVNTLPGMTATSLVPKIAAGLGLSFPDLCERILDGAALKA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_TERTT
Sequence: MTNTTTIDYSLDASWILPVVPHQRLFKDCSLLISRDRIHSIVPTSQSLRDYTVRERISLPGQLLMPGLINCHGHAAMTLLRGFADDMPLETWLKEHIWPVEAQWAGEEFVRDGGELAMAEMLLSGTTCFADMYFFGEALASAVHKAGMRAQLYFPIVDFATAWAQSPDEYIHKGLKLRDTYRSHPLINVHFGPHAPYTVGDAPLERIAVYADELHAQVHIHLHETPEEIESSIKEFGKRPLQRLADMGLLTPLTHCVHMTQTSAEDIALLANSGAHVIHCPRSNLKLASGSCPTAALTQQGVNVALGTDGAASNNSLDMFAELQAAALFGKLVAGDAAAIDAHSAIAMATINGAKAIGLEDQLGSLEPGKQADVIAIDMNDLDLQPVHNPVSQLVYTQMGHRVSNVWVAGEQLVKSRDLTTLSRKEIAANAAQWREKLGAKR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: Y2718_MARN8
Sequence: MKLIIVSGRSGSGKSTALHVLEDLGFYCIDNLPIGLLFPLTREAATQEAPGRLKKMAVSIDARNLSAELANFETIYQQLKQTGVELEIIFLDADEQSLLQRFHATRRKHPLSDDKTSLREAITNEKQLLEPLSKLADLYVNTTGLSMYELRDMIKQRVAGRKDQELALLFQSFGFKHGVPVDSDYVFDVRCLPNPYWDTSLRKHTGVDQPVIDFLEREPLTRQMVDDLTGFLNTWLPSFADSNRSYMTISIGCTGGQHRSVYVCEQLGRYFRDNYRNVQVRHTELPHLQARGEI
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Maqu_2718.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: YAP4_YEAST
Sequence: MLMQIKMDNHPFNFQPILASHSMTRDSTKPKKMTDTAFVPSPPVGFIKEENKADLHTISVVASNVTLPQIQLPKIATLEEPGYESRTGSLTDLSGRRNSVNIGALCEDVPNTAGPHIARPVTINNLIPPSLPRLNTYQLRPQLSDTHLNCHFNSNPYTTASHAPFESSYTTASTFTSQPAASYFPSNSTPATRKNSATTNLPSEERRRVSVSLSEQVFNEGERYNNDGQLIGKTGKPLRNTKRAAQNRSAQKAFRQRREKYIKNLEEKSKLFDGLMKENSELKKMIESLKSKLKE
What is the function of this protein?
Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements.  According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, and protein synthesis.  It may also be involved in pleiotropic drug resistance.  When overexpressed it confers increased resistance to cisplatin, the DNA-alkylating agents methylmethanosulfonate, and mitomycin C, the antimalarial drugs quinidine, mefloquine, and chloroquine, and increases cellular tolerance to sodium and lithium.  Preferentially binds 5'-TTACTAA-3'.
What are the official names of this protein?
AP-1-like transcription factor YAP4, Chromosome instability protein 5, Transcription activator CIN5.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDH_SYNC1
Sequence: MVKPKIALIGGGQIGNSIAHLAAMRELGNVIMFDIKDGLAQGKCLDIAQAAPISNFDVQLCGSNDISCIAGADIVVVTAGIPRKPGMTREDLIEINARIMVTVAEGIKTHAPESIVIVLSNPLDAMVTLCQKITGFPTQRIMGMAGVLDSARFASFIAWELGVSVRDVNAMVLGGHGDAMVPIVRFANVNGIPALELLKNKYGDEDKARQVMAGLVERTQDAGGEVVHLLQTGSAFISPATSAIAMVEAVIHDQKRLLPVCAMLDGQFGISGYYVGVPCILGVGGVERIVEFELTEDEQALLDHSVGEVKKLVDSLPL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: LPXC_PSEF5
Sequence: MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRADLDPVVQIPARAENVGETTMSTTLVNGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLEEQDAAKKFIRILREVTVEDGDKRATFVPFDGFKVSFEIDFDHPVFRDRTQSASVDFSSTSFVKEVSRARTFGFMSDIEYLRKHNLALGGSVENAIVVDSDGVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFKGFKSGHALNNQLLRKLIEQKDAWEVVTFEDASTAPISYMRPVAAV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PDXY_ECOLI
Sequence: MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAKPEHYFSATKL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP in vivo, but shows very low activity compared to PdxK.  Displays a low level of pyridoxine kinase activity when overexpressed, which is however not physiologically relevant.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase, Pyridoxal kinase 2, PL kinase 2.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: AK_HELPY
Sequence: MLIVQKYGGTSMGSIERIHNVAQRVLESVTLGHQVVVVVSAMSGETDRLLEFGKNFSHNPNKREMDRIVSVGELVSSAALSMALERYGHRAISLSGKEAGILTSSHFQNAVIQSIDTKRITELLEKNYIVVIAGFQGADIQGETTTLGRGGSDLSAVALAGALKAHLCEIYTDVDGVYTTDPRIEEKAQKIAQISYDEMLELASMGAKVLLNRSVELAKKLSVKLVTRNSFNHSEGTLIVAEKDFKGERMETPIVSGIALDKNQARVSMEGVEDRPGIAAEIFGALAEYRINVDMIVQTIGRDGKTDLDFTIVKTQIEETKQALKPFLAQMDSIDYDENIAKVSIVGVGMKSHSGVASIAFKALAKDNINIMMISTSEIKISVLIDIKYAELAVRTLHAVYQLDQ
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: MDM34_NEUCR
Sequence: MAFNFNWSPLTADAGFYERARDLLTTALNKSPKPPIIVDDIFVTELNLGSVPPDLEILEIGDLAEDRFRGIFKMCYSGDAFLTLATRVQANPLNTYISAKPSFTSPEPLTASSSLTIPLQITLSEIKLSAFIILVFSKQKGLTIVFRNDPLESLKVSSTFDSIQFVRDYLQKTIEMKLRDLIMDELPAIIHRLSLQLWCPDQVPKEDEEAKEESDAAINPLATPPLDAVDAHGHRLDPAEISSLSLDGGPETQSLFSQKNLEKMDALASAHRTSSLLTPNILEVVFRAWAGQSDKPDATATPASTPNLHRTSSYQGSVHTYTFSDNSSQASGHALSRPTLVSMGSATTGLSLGSGRHSKAGRKKKMRVVNLRSKTAVSEPVSEIGSTSSQAGDSHTEASTRTPMSEPVIPTTIREVPEDDLAASQSKVRFRPPTDATTSARASESSGPRAAVPSVPVTAQPSRATSSQEHVYTRQPSMFPSSPAPQTSAQEMPPSYSSRVSEKAESTASIYADAKGQQQQFQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQWGRAGPQPDMSSVILEQAWITKIAGEIARRVYDEKNRNPAFWEDSHQHDIPPPAYEPR
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm-1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: NTA_AVIPU
Sequence: GDCHKFWGWCRDEPDPCCEHLTCSTKHGWCVWDGSF
What is the function of this protein?
Inhibitor of voltage-gated potassium and sodium channels.  Among other potassium channels, it selectively inhibits Kv10. 1/KCNH1/EAG1 (IC(50)=236 nM) by shifting the voltage dependence of channel activation in a depolarising direction, it shows a maximum inhibition of 80% at saturating concentrations, it shows fast on-rates, and is poorly reversible.  It also slightly affects channel inactivation, when the membrane is highly depolarised (>+80 mV).  It shows similar potency on Nav1. 7/SCN9A (IC(50)=222 nM) and lower potency on Nav1. 2/SCN2A (IC(50)=519 nM).
What are the official names of this protein?
Mu/kappa-theraphotoxin-Ap1a, Mu/kappa-TRTX-Ap1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHFB_NITHX
Sequence: MIKSELVQRIAEHNPHLYQRDVENIVNAILDEIVTALARGDRVELRGFGAFSVKHRPARAGRNPRTGEHVPVDQKSVPFFKTGKEMRERLNRENATSEASA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.