PharMolix/UniProtQA huggingface dataset:
Protein: R144B_HUMAN
Sequence: MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation.  Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism.  However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF144B, IBR domain-containing protein 2, RING finger protein 144B, p53-inducible RING finger protein.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF144 subfamily.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm. Note=Mostly cytosololic, accumulates in submitochondrial domains specifically upon apoptosis induction, in synchrony with BAX activation.
Protein: CYSD_SHEB5
Sequence: MAGRELSHLQQLEAESIQIIREVAAEFDNPVMLYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTGWKFKEMIAFRDAQAKKFGFELLTHINPEGLAQGINPFDHGSAKHTDIMKTQGLKQALNQYGFDAAFGGARRDEEKSRAKERVYSFRDRHHRWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIELVPLYFAAKRQVVERGGQLIMADDERMKLAEGEQFKEEVVRFRTLGCYPLTAAMHSEADSLEKIIEEMLLTRSSERQGRLIDSDQSASMEQKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: Y6576_DICDI
Sequence: MSIFSSLSSLSTGSLKSSVSSIENGSSSGSFGSNETSGWGQHHWNSCHPCPPPRPICRPCPPCRPEPRCHRY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285569.
Protein: ISPH_CORGL
Sequence: MSSPVISPETKTGKKILLAAPRGYCAGVDRAVETVERALEEYGAPIYVRKEIVHNRYVVDTLAEKGAIFVNEASEAPEGANMVFSAHGVSPMVHEEAAAKNIKAIDAACPLVTKVHKEVQRFDKQGFHILFIGHEGHEEVEGTMGHSVEKTHLVDGVAGIATLPEFLNDEPNLIWLSQTTLSVDETMEIVRELKVKFPQLQDPPSDDICYATQNRQVAVKAIAERCELMIVVGSRNSSNSVRLVEVAKQNGADNAYLVDYAREIDPAWFEGVETIGISSGASVPEILVQGVIERLAEFGYDDVEEVTSAAEKIVFALPRVLRHKN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NRAM_I01A1
Sequence: MNPNQKIMTIGSICMVIGMISLVLQIGNMISIWASHSIQKMNQHQTEPCNQSIITYENNTWVNQTYVNISNTNFLTEKVVASIALSGNSSLCPISGWAVYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNSILRTQESECACVNGSCFTVMTDGPSNGQASYKIFKIEKGKVVKSVELNAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFDQNLEYQIGYICSGVFGDNPRPNDGTGSCDPVLPNGAYGVKGFSFKYGDGVWIGRTKSTNSRSGFEMIWDPNGWTGTDSNFSLKQDIVAMTDWSGYSGSFVQHPEMSGLDCIRPCLWVEPIR
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: DCUP_CHLMU
Sequence: MAGFYDIISPSNQHRPPVWLLRQVGRYMPQYQELKTNRPLKELFLDTESIIEATLLGPSLLGVDAAIVFTDILSILEGFAIEYRFAPGPEIIYSPHQPFVFTEDPFSTFSFLIEAIQKLTKRLTVPLIAFAASPFTLASYLIEGGASKDCSKTIAFLYQYPDKFEALLNEIIKGTAIYLQLQVQAGASAVQLFESSSLRLPPSLFSKYVVSPNAKLIRLIKQRENPPVSLFCRCFYQEFLSLYATGADTLHPDYHVELSEIYRQLGDPGSIQGNFDPALLLLPQDLLIAHLETYLAPLKQQSHYIFNLGHGILPQTPLENVQAVVKCLTSISTS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1241_BACAN
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFETQDEQLESIVNKLHTIASKTNPFTLHVGKVGSFAPVNNVIYFKVEKTPELTFLNEEMHSGFFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BA_1241/GBAA_1241/BAS1148.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: PYRG_BURL3
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTLVPYVATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISMFSNVPEDAVISVWDADSIYKIPQMLHDQGLDRIICEELKLSPKDADLTMWSELVEKLENPKHEVTIGMVGKYVDLTESYKSLIEALRHASLHTSTKVNIEYIDSEEIETNGVDSLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARNVVGLKQANSTEFEPDTPERVVALITEWYDRDGKVETRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRFVPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALANKQARGV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SQT1_YEAST
Sequence: MEPQEEFITTEEVEQEIVPTVEVEQDVPVDIEGENDDDDEMMNDDEEALEVDMSNNSLTYFDKHTDSVFAIGHHPNLPLVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLASQMQEVEEIVWLKTHPTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQDCSMGEFINTDKGENTLELVTCSLDSTIVAWNCFTGQQLFKITQAEIKGLEAPWISLSLAPETLTKGNSGVVACGSNNGLLAVINCNNGGAILHLSTVIELKPEQDELDASIESISWSSKFSLMAIGLVCGEILLYDTSAWRVRHKFVLEDSVTKLMFDNDDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFILLHPVANTGTEQKRKVITAGDEGVSLVFEVPN
What is the function of this protein?
May be involved in the late step of 60S ribosomal subunit assembly or modification in the cytoplasm.
What are the official names of this protein?
Ribosome assembly protein SQT1.
Protein: SPRT_ECOK1
Sequence: MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWMMESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGEQLVAK
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_GEODF
Sequence: MASLKSIKKRIVSVKNTGQITKAMKMVSAAKLRRAQENVVAARPYAAKLGEVLGRLSRNQDADSSPLMIKRTTGKALLIVVTSDRGLCGGFNANLCKAAERFVKERGAEFTDLSIMTIGRKGYEFLKNRQKIRKNFGTVFSNLNYQTAALLAQEVIQGYLDEEFDEVFIIYNAFRSVMSQDITLEQLLPVTPPEAADEEYAPEYIYEPSKSELLGELLPKHIEVQIFKSLLESVASEHGARMTAMDSASKNANEMIGKLTLQYNRARQAAITTELMEIISGAESIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PBL1_ARATH
Sequence: MGSCLSSRVLNKSSSGLDDLHLSSCKSSSSATAHKTEGEILSSTTVKSFSFNELKLATRNFRSDSVVGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQRLLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNSQYKPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQDSVVKPANVDPLKVKDTKKLVGLKTEDKYQRNGLNKKTVGL
What is the function of this protein?
Contributes to pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling, including calcium signaling and root growth inhibition, and defense responses downstream of FLS2 (PubMed:20413097, PubMed:25522736).  Acts additively with BIK1 in PTI defenses (PubMed:20413097, PubMed:25522736).  Seems not required for flg22-induced MAPK activation (Probable).  Required for Pep1-induced defenses (PubMed:25522736).  Pep1 is an endogenous elicitor that potentiates PAMP-inducible plant responses (PubMed:23431184, PubMed:25522736).  Required during SCOOP small peptides (e. g.  SCOOP10 and SCOOP12) perception and signaling; receptor-like cytosolic kinases (RLCK) activated by BAK1/SERK3 and SERK4 coreceptors when associated with MIK2 upon the perception of SCOOP peptides (PubMed:34535661).
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL1, BIK1-like protein kinase, PBS1-like protein 1, Protein CHANGED CALCIUM ELEVATION 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Myristoylation and proper targeting to plasma membrane is essential for signaling function in response to pathogen-associated molecular pattern (PAMP) such as flg22.
Protein: NUOI_CROS8
Sequence: MTLKDIVVGFGTQLRSIWMIGLHAFSKRETRMYPEEPVYLPPRYRGRIVLTRDPDGQERCVACNLCAVACPVGCISLQKAETVDGRWYPEFFRINFSRCIFCGMCEEACPTTAIQLTPDFELGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGDAENEAKPIDVKGLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYFA_SORC5
Sequence: MSGPELGRLIDEVDRTVDVQFAAAGDLDELNRLYASLLGRRGSLNALMKQLPGAAPEERKALGQRLNAVKGRVERAREEATARIKRAARDRELSAPPLDITLPGRWRAPGRPHPIMRTLDEIVDIFVGLGFDVAEGPQIELARYNFDLLGFPADHPAMDMHDTFYMAGDPGQNVLLRTHTSPVQVREMLSHPPPVMIVAPGVVYRRDDDASHSPMFVQIEGLVVDRDVSLADLKGLLEVYSRRMFGEATRTRFRPSYFPFTEPSAELDVSCLVCFGENRACPQCKGTGWLEVLGCGMVHPTVLRNVGIDPEEYTGLAFGIGVDRTANMKFAVDDIRAFYENDVRFLGSL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTPSL_METRA
Sequence: MEKQRLKAQLSSLRVPLFSVPWPGQCSNKAEVVEARMMKWADEHNLLVTDEYRNRVIRTRYGLLAARCYPNAGEELLQVIADYLVWFFLTDDLFVDRVEVATDETIRNLTAMVDVLDLNVAGSPPVFGELAWLDVCQRLRRLLQVEAFERFAQGMRLWATTAALQILNHLRPTSVGIQEYQTIRRHTSGMNPCTSLADAANKGSVQACEFYDADVQTLVRQTNNIVSWANDIQSLRREIHQPGQFRNMVTICAQQGQSIQDSVETTATRVNKEIAGFCGLADAVTARPISDELHGLIDGLKYWIRGYLDWVAHDTMRYADHFIESDADDRRFSAPDLSLLNKSCSSVTESTSSLV
What is the function of this protein?
Terpene synthase that catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into sesquiterpenes which are important for fungi-environment interactions (PubMed:31239482).  Produces a mixture consisting of 9 sesquiterpenes including gamma-cadinene, delta-cadinene, alpha-cadinene, alpha-cadinol, beta-elemene, (E)-beta-caryophyllene, germacrene D, nerolidol and an unidentified oxygen-containing sesquiterpene (PubMed:31239482).
What are the official names of this protein?
Sesquiterpene synthase MAA_08668, Bacterial terpene synthase-like protein MAA_08668, BTPSL.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TTTP_LAMBD
Sequence: MKHTELRAAVLDALEKHDTGATFFDGRPAVFDEADFPAVAVYLTGAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDAWMESRIYPVMSDIPALSDLITSMVASGYDYRRDDDAGLWSSADLTYVITYEM
What is the function of this protein?
Plays an essential role in tail assembly by capping the rapidly polymerizing tail once it has reached its requisite length and serving as the interaction surface for the completion protein.
What are the official names of this protein?
Tail tube terminator protein, TrP, Gene product U, gpU, Minor tail protein U, Tail sheath-stabilizing protein, Tail-to-head joining protein, THJP.
What is the protein family that this protein belongs to?
Belongs to the lambda-like tail terminator protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CFI_IPOPU
Sequence: MSAPPCVAEVKVESYVFPATVKPPGTAKTLILGGAGARGLNIDGKFVKFTAIGVYLEADAVPSLAVKWNGKSVEELTDSVQFFRDIVTGPFEKLTRITMILPLSGKQYSEKVTENCVAFWKAAGMYGDAESKAIDKFNDVFSDQMFPPGASIFFTQSPLGSLTVSFSKDGSMPEIASAVIENKPLSEAVLESIIGSKGVSPEAKQSLAVRLSEMFINGGDAISGKVGVENDVIPQTVVVSK
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: DGAT2_ARATH
Sequence: MGGSREFRAEEHSNQFHSIIAMAIWLGAIHFNVALVLCSLIFLPPSLSLMVLGLLSLFIFIPIDHRSKYGRKLARYICKHACNYFPVSLYVEDYEAFQPNRAYVFGYEPHSVLPIGVVALCDLTGFMPIPNIKVLASSAIFYTPFLRHIWTWLGLTAASRKNFTSLLDSGYSCVLVPGGVQETFHMQHDAENVFLSRRRGFVRIAMEQGSPLVPVFCFGQARVYKWWKPDCDLYLKLSRAIRFTPICFWGVFGSPLPCRQPMHVVVGKPIEVTKTLKPTDEEIAKFHGQYVEALRDLFERHKSRVGYDLELKIL
What is the function of this protein?
Involved in triacylglycerol (TAG) synthesis.  Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA (PubMed:23770095, PubMed:24663078).  Can use oleoyl-CoA, linoleoyl-CoA and linolenoyl-CoA as substrates.  Has substrate preference for linolenoyl-CoA or oleoyl-CoA compared to linoleoyl-CoA (PubMed:23770095).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, AtDGAT2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet.
Protein: YKZ2_SCHPO
Sequence: MPSYTHMPYVRPSAILLGIAFDHAASFLVYGPLMGDIWKRAMSTAPHVEYDAGSKTKKVATTYVSNFLSTAVQSYSIAALLQLTGTVTLKGAFFVGLYVFGASGLPDVVDYMFTESRGTPYILVKTISSLVKSVGLSVALIGYGVRRI
What are the official names of this protein?
UPF0591 membrane protein C15E1.02c.
What is the protein family that this protein belongs to?
Belongs to the UPF0591 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVB_STAAT
Sequence: MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIKAAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTPRVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNGGPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HRCA_STREM
Sequence: MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQFAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDYAGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SODF_PLAFX
Sequence: MVITLPKLKYALNALSPHISEETLNFHYNKHHAGYVNKLNTLIKDTPFAEKSLLDIVKESSGAIFNNAAQIWNHTFYWDSMGPDCGGEPHGEIKEKIQEDFGSFNNFKEQFSNILCGHFGSGWGWLALNNNNKLVILQTHDAGNPIKDNTGIPILTCDIWEHAYYIDYRNDRASYVKAWWNLVNWNFANENLKKAMKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe], FeSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_SALAR
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLNRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLMENVDAFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFELQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHRE_PEA
Sequence: MKLIAVLLLVVLATATTATAADADALQDLCVADYASVILVNGFACKPASNVTAEDFFSNLLVKQGATNNTFGSLVTGANVQRIPGLNTLGVSMARIDYAPGGLNPPHTHPRATEMVFVLEGQLDVGFITTTNQLIAKTIAKGETFVFPKGLVHFQKNNGWEPATVIAGFNSQLPGTVNIPLTLFNATPPVPDNVLTKAFQIGTKEVQKIKSKFAPKK
What is the function of this protein?
Putative receptor for bacterial rhicadhesin, an attachment protein of rhizobiaceae.
What are the official names of this protein?
Rhicadhesin receptor, Germin-like protein.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall.
Protein: TM10A_DROME
Sequence: MDTTEKALKEVTPAMLSLNNCPGTTPGTPMSKNQLKKQRKLAEFAELRKLRREREREKKKQKRREAKELGLPVRTGPSRKELKKRQLADGGKSGLSVAIDLDYDDLMQERDIVKCVKQCLRIYTINRRSPQPGNLHFTGIRRNGHIHESFKKNEGWENWHVQYYFDRGHTDIFEHSQLVYLTCESDRVLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKTRAVLSTYHVFELLTKVAAGQDWTTAILETIPMRKGAKAKITDKKEPNHCLEQQDEKQKQEAESDKPTLTAVESEIESHSLDS
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs.
What are the official names of this protein?
tRNA methyltransferase 10 homolog A, RNA (guanine-9-)-methyltransferase domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
Protein: RL18_CELJU
Sequence: MSEKKEARLRRARRARAKIRELGVTRLAIHRTPRHIYAQLISGDGSTVIASASTLDKDLRSGKTGNADAAKAVGALIAERAKAAGVTQVAFDRSGFKYHGRIKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.