PharMolix/UniProtQA huggingface dataset:
Protein: KPYM_XENLA
Sequence: MSEAGSAFIQTQQLHAAMADTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEMLKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESLASNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATMRITLDDAFQENCDENVLWVDYKNLTKVVKPGSKIYVDDGLISLLVKEIGPDFCVTEIENGGMLGSKKGVNLPGAAVDLPAVSSKDIQDLQFGVEQDVDMVFASFIRKAADVHEVREVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRVSPLTRDPTEATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPIISVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDSRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPVP
What is the function of this protein?
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP.
What are the official names of this protein?
Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, CTHBP.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: RSMH_ESCF3
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_MYCMM
Sequence: MNVTKPATQRPKLPSVGRLGLVDALAGARLAELGWTEHDDQAHVDLLWSLSRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAVLGSSLSLGDHLVANPQSWKLLRGKVALPSHAALLESFVDLAEEVAAAPASAVHRLRALHRDHVLVLAGLDLAATVEDEPVLPFTVVAAHLADIADAALAAALRLAEKTVCRDRTPPRLAVIAMGKCGARELNYVSDVDVIFVAERADPISIRVAGEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQRWAKTWEFQALLKARAAVGDAELGQSYLAALMPMVWTACERDDFVAEVQAMRRRVEQLVPADIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVASTVDALSALGEGGYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEFDDEEAVRWLARAAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPLLESIAPAGLEIAGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRRARVQSVLLPRLLDWLSYAPDPDGGLLAYRRLSEALATQSWYLSTLRDKPTVGRRLMHVLGTSAFVPDLLMRAPEVIQNYGDGRTGPKLLETEPAAVARALIASAGRYSDPLRAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVWVAVLQSALEAMIRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYVCEPASGVTDAQAVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGPLVRTLASYEAYYAQWAQAWEIQALLRAHAVAGDAELGQRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADPNTHTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLVAEDEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWHNDDGGEFLDNYLRVTRRAKAVVRKVFGS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: MRAZ_FINM2
Sequence: MFINEYFHNIDSKGRVIMPSKFRDEIGEEFYITKGMDECLFVYPVSAFIQMTEKLNKLSLTRRQARAFSRVFFSGASNQEIDKQGRFLIPQSLRSYADIKKEVAIIGVSNRIEIWDKEKWEQYSNDSSLNYDDLADGLNDLDL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPO5_PYRFU
Sequence: MAGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDVIEIKRKSPTAGVYYYYRVVVED
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_DIOEL
Sequence: MMFEHVLVLSVYLFSIGIYGLITSRNMVRALMCLDLILNSVNMNLVTFSDLFDSRQLKGDIFSIFVIAVAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL15_METS4
Sequence: MKLNEIRDNEGATKDRMRVGRGIGSGKGKTAGRGVKGQKARTGVAIKGFEGGQMPLHRRLPKRGFNNPGATDLNEVNVGRIQQAVDSGKLDPSAPVTVEALVAAGVVSRVRDGVKILGVGELTASLTFQVARASKSAVAAIEKAGGSVTQSLAATDGAVASA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PS9_PINST
Sequence: AMASSLLSGWGGPTTLLVAPM
What are the official names of this protein?
Putative NADH dehydrogenase subunit PS9.
Protein: O4F17_HUMAN
Sequence: MVTEFIFLGLSDSQGLQTFLFMLFFVFYGGIVFGNLLIVITVVSDSHLHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGGSEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVAWGIGFLHSVSQLAFAVHLPFCGPNEVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYTIILMTIQHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFPIKSLDKFLAVFYSVITPLLNPIIYTLRNKDMKTAIRQLRKWDAHSSVKF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4F17, Olfactory receptor 4F11, Olfactory receptor 4F18, Olfactory receptor 4F19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HPRK_BREBN
Sequence: MRKTNVSHLVDHFNMTILSGEEGLGREITVTDLSRPGLQLAGYYSYFAEERIQLFGLTEINFFQTLTPEERLERMNFLMQSQVPCFCVTRNQMVPEEMIDVSNRLGVPVLQSPLATTTLVGKVTNFLENRLAPTTTIHGVLTDIYGVGVLIMGSSGIGKSEAALELVKRGHRLVADDAVEIKQTQGGQLSGSAPELIQHLLEIRGVGIINIMTMFGAGAVRNVKNIEMVVQLELWEPHKMYERLGLDEETLKIMDTEIPIITVPVRPGRNLAVIIEVAAMNFRLKRMGYNAAMHFTRKQSNAILEDADSDL
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: OLFL3_RAT
Sequence: MGPSAPLLLFFLLSWPGSLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKERETLRTEADSISGRVDRLEREVDYLETQNPALPCVELDEKVTGGPGTKGKGRRNEKYDMVTDCSYTISQVRSMKILKRFGGSAGLWTKDPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLTMAARKASRIRVPFPWVGTGQLVYGGFLYYARRPPGGAGGGGELENTLQLIKFHLANRTVVDSSVFPAERLIPPYGLTVDTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALSYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMKKKEEEV
What is the function of this protein?
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development.  Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side.  Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity).  May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes (By similarity).
What are the official names of this protein?
Olfactomedin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the OLFML3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_ERWT9
Sequence: MAEKVAVLLGGTSAERDVSLLSGAAVLKGLKEAGIDAHAIDIRDFPAMRLKEEGFDKAFIALHGRGGEDGTLQGVLEFLAIPYTGSGVMASAITMDKLRSKYLWQGCGLPVSPFVALNRAQMDAGLDAQLMTSIDALGLPLFVKPSREGSSVGISRVNQASELQAALQEAFRFDDEVLVEAFLSGPEYTVGVIGTDILPSIRIQTASEFYDYDAKYLSDETQYFCPSGLSADQEAELRELTIAAWRALGCSGWGRVDVMMGADGQFYLLEVNTSPGMTSHSLVPMAANQAGMSFSQLVARILELAD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3544_METJA
Sequence: MFIKWGDRLMTKTLHLTKVTIRNFRSIKVAHINNIGDIAVFVGANESGKSNILKALNWFGTDKPLGGDDIPVEFLGKENKEYSKKPIIEAYFEIVNKDKFKEKIISNIKEILEVIKVDINEDILINFEDMLNKIQFLKFEKYADGLFKTYIYDDQLEDITKEFYDCFKNVISKKTPLDLFNLIYEEVLKEEVKKQNIPENQISNAVANIRGNPNFNNHYRKILDEIRTLNTFEEFYEICKRIENIVKSIPNTSVSISIPGRNIQLNPYNIFTEILTKFNSIVTIAFINLKPKFVYLDEEMELKGAVIKNTSWSNTLKEENKTTLLMPDFLE
What are the official names of this protein?
Uncharacterized protein MJECL44.
Protein: AIM24_COCP7
Sequence: MEPMNYLVRRGFRPSAWKYGKWRPIGKTVSERRRISIQPVPSVESNTVNASYLPAASTPSSVTSPGLCIVSNDASFEVLGSPYSLLSVSLSASQNLYTRRGTLVGLTGKSENVVSTLRLLEPLRRAALRMPFLYQKISSASPVNALISVRSPITSFAVVQLDGTVDWMITQRDALLSWTGHALTVKPTLNRELSLVHWGSSKVTGRGLLAVVGKGQVYSINLRAGERYIAHPSNVVAYTINSHWPRPFRFKSTSLKFQIPKLGLGTLLMKSNFLRNLADSDTWKATMRIFHTVRTWARRTIWGDRLFLQFEGPATVLIQSRASRIAESLTAREVNEIASTQPGVTREATETVEARLEKQSPPPAKDDGMKTVGQSVASVRRDGKVEFEKVDGV
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYD_XYLFM
Sequence: MRTHFCGLINETLIGHTVTLAGWTDVARNLGGVCFIDLRDHEGIVQITVDSRAIDQNNSELFKVASGLSYEDVLQVEGVVCARHAVNDKIKTGKVEVIATKIKILNKAAPLPFHAHENPGEDIRLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDMHGFQDIETPILTKATPEGARDFLVPARMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQLEFTQLDMEFAFVSERDVQDFVEEMIRRVFKEVAGIELDTTFPRMTWKEAMRRFGSDKPDLRINLELIDVAALVADSTFTPFTDAVAHPNGRVAALRIPSGTVLSRKQIDEYAAYTAKYGATGLAYAKLAPTGEITSPIAKFFSEDAFASLLSHIGAEKGDIVFFGAGNYNKVSDFMSALRLKAGKDFALITADWRPLWVTDFPMFEWDEEAQRYVALHHPFTAPAAIDDIDELRAHARTALSRGYDMVLNGNEIGGGSIRIHRPEMQRAVFELLGITEDEARAKFGFLLDALNYGAPPHGGIAFGIDRIAALIAGTESIRDVIPFPKTTGAQCLMTDAPSPISEEQLSEIHVITKKTTP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6C_CERDE
Sequence: MDLPGPIHDILLVFLGSGLILGGLGVVLFTTPIYSAFSLGLVFVCISLFYIPSNSYFVAAAQLLIYVGAVNVLIVFAVMFMNGSEYYKDFHLWTVGDGITSLVCTSILFSLITTILETSWYGIIWTTRSNQIIEQDLTSNVQQMGIHLSTDFYLPFELTSIILLVALIGAIAMARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PLSX_STRPD
Sequence: MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKINSYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTGALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSFYAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVADVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLDYSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVND
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MHPB_ECO57
Sequence: MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: RL27_OPITP
Sequence: MAHKTGQSSSSNGRESKSKRLGVKTFGGQKVLAGTIIIRQRGTRLHAGRNVGTGRDWTLFALKDGVVKFDKPHRRVEIVAS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MALT_ECODH
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: TRHO_RICRO
Sequence: MNEKIAILSAYSFVNIEEPANLIPKLLLLGKRKYIRGTILLANEGFNGSFSGSYENVNLVLEELIKLTGPKDVNVKINYSDVHPFQKLKVRLKKEIIAMNVDDLNVDLFKGEYIEPKDWDEFITKQDVIVIDTRNDYEVEVGTFKSAINPNTKTFKQFPAWVQQNQELLKGKKIAMVCTGGIRCEKSTSLLKSIGYNEVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVTDDLSPVERHWLQR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MIAA_XYLFM
Sequence: MPADTRPAAIVLMGPTASGKSQLAIDIAKRWGGEVISVDSVLVYRGLDIGTAKPNAAMRASVPHHLIDICEPWETYSAADFAHDARAAIDMIVRRGALPILTGGTGLYFRALLAGLSDMPPAHPEIRAMIAAEAKRDSWATLHTRLAEVDAITAARIHATDPQRIQRALEVYLVSGRSMSDWQNQPPKQRLPLRVLKLVLAPTHRKVLHFRIAQRFKAMLDNGLLAEVNALRTHPSIHAMARPLDLPAMRAVGYRQCWEHLDGMYTAEMLYQRSVAATRQLAKRQLTWLRGELDALWFDPEHDQSRIEKVMEAFLNR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ARCC_ECO57
Sequence: MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_AYWBP
Sequence: MAIKKYKPTTNGCRNMSVSAFSEITTQTPERSLLVSHKDQAGRNNQGKITVRHRGGGVKRKYRLIDFKRNKDNIVGKVATIEYDPNRSANIALIHYVDGEKRYILAPKGLTVGMQIVSGKETDIKVANCLPLMNIPVGTTVHNIELKPGKGGQIARSAGSSCQIISREDKYVLLRLQSGEVRKVLATCRATIGEIGNESYKLINYGKAGKKRFLGIRPTVRGSAMNPNDHPHGGGEGRAPIGRKSPMTPWGKKARGVKTRDRKKASNALIIRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ILKAP_RAT
Sequence: MDLFGDLPEPERPPRPSAGKEAQEGPVLFEDLPPTSSTDSGSGGPLLFDGLPPAGSGNSGSLATSGSQVVKNEGKGAKRKAPEEEKNGGEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKPAVDARYEAACNRLANKAVQRGSADNVTVMVVRIGH
What is the function of this protein?
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation.  Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling.  Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation (By similarity).
What are the official names of this protein?
Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, PP2Cdelta.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_PSEFS
Sequence: MSDPRYQIDVSVVTRFLADQSQPEQNRFAFAYTITVKNNGLVPAKLLSRHWVITDGDGQVEEVRGAGVVGQQPLIDIGASHTYSSGTVMTSKVGTMQGSYQMKATDGKLFDAIIAPFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: HSLU_RICPU
Sequence: MKATKTTYKKDPMGLTPSQIVNELNRFIVGQEKAKKAVAIALRNRCRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKTLAKTKVDIHAREKAIERILDSLVGKTSSSETREKFKEKILNGELDDTEIEISVADTTPVGGGSFEIPGMPGASMGVLNLGDMIGRALGSSKTKTKKMLVKDAMAIIIPEESEKLIDQEKIIQQAINLAENDGIVFIDEIDKIASTGSSGAKNAEISREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNSLTKDDMIKILLEPETSLIKQYSALIGTEDVRLEFAASAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKGKKITIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_VIBCH
Sequence: MTDKNDALTLKKRFRGYFPVVIDVETAGFNAQTDALLEICAVTLSMDENGDLHPASTIHFHVEPFEGANLEKAALEFTGIYDPFSPLRGAVSEDHALKEIYKLVRKEQKAADCSRAIIVAHNAHFDHSFVMAASERCKLKRVPFHPFATFDTATLSGLAFGQTVLAKACKTAGMEFDNREAHSALYDTQKTAELFCTIVNQWKALGGWPLVNDDEDNNNDADLD
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.