PharMolix/UniProtQA huggingface dataset:
Protein: SG196_MOUSE
Sequence: MGQQHGTRNGLTHRELPRGVGLLLAMALMNVALYLCLDQLFISPGRSTADSRRCPPGYFRMGRMRNCSRWLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSRLTRLEMKEDFLHGLQMLKSLQSEHVVTLVGYCEEDGTILTEYHPLGSLSNLEETLNLSKYQDVNTWQHRLQLAMEYVSIINYLHHSPLGTRVMCDSNDLPKTLSQYLLTSNFSIVANDLDALPLVDHDSGVLIKCGHRELHGDFVAPEQLWPYGEDTPFQDDLMPSYNEKVDIWKIPDVSSFLLGHVEGSDMVRFHLFDIHKACKSQIPAERPTAQNVLDAYQRVFHSLRDTVMSQTKEML
What is the function of this protein?
Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose).  Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.  Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity).
What are the official names of this protein?
Protein O-mannose kinase, POMK, Protein kinase-like protein SgK196, Sugen kinase 196.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NUOH_BORPD
Sequence: MEWLDILESHGQALLGPTAWLVLWTIVKIVVIAVPIILCVAYLTYWERKMIGWMHVRLGPTRVGFRGLLQPFADVFKLLTKEVVVPTQANKILFVVAPVVTLMPALAAWAVVPFGPEVVLANVNAGLLYVMAITSIGVYGVIVAGWASNSKYAFLGALRASAQMVSYELAIGFVLVTVLLVSGSLNMSEIVLGQTRGWFAEHGLTFLSWNWLPLLPLFVIYVISAVAETNRHPFDVVEGESEIVAGHMVEYSGMAFALFFLGEYANMILLSCMASIMFLGGWTSPIDIAPLTWIPGWIWLGIKTFCVVSLFVWFRASFPRYRYDQIMRLGWKIFIPLTGVWLVVVAIWMQTPWNIWR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_YERPG
Sequence: MTSSNLIKQLQERGLVAQVTDEDALAERLAQGPISLYCGFDPTADSLHLGHLVPLLCLKRFQLAGHRPVALVGGATGMIGDPSFKASERKLNTEDTVNEWVEKIRHQVSPFLDFDCGENSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDSGISFTEFSYNLLQAYDFACLNKNHGVALQIGGSDQWGNITSGIDLTRRLHQQQVYGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSLEEINALEEEDKNSGKAPRAQYVLAENVTGMVHGPEGLAAAKRITDSLFSGDLHDMTEADFAQLAQDGMPTVELNRDADLQQALVNAELVPSRGQARTMIGSNAVAINGEKQADPEYVFTDADRLFGRYTLLRRGKKHYCLISWL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_PSE14
Sequence: MKSCEVNFDGLVGPTHNYGGLSYGNVASQSNSQQCANPREAALQGLAKMKALMDLGFTQGVLAPQERPDVAGLRQLGFIGSDEQVIEKAARQDMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFADAKHFAHHPALPPVAQFGDEGAANHTRFCQDYGQPGVEFFVFGRSAFDTRYPAPQKYPARQTLEASRAVARLHGLSEGGVVYAQQNPAVIDQGVFHNDVIAVGNGEVLFYHEDAFLNTEPMLNELRDKLGRVGGQLRAICVPRAEVSVQDAVRSYLFNSQLLSRPDGSMLLIVPQECQANASVWAYLQRLIADDSPVAQVKVFDLKQSMQNGGGPACLRLRVALKETELAAVNPGVIMTAPLYDTLTQWVDRHYRDRMSENDLADPRLLIQCRTALDELTQILKLGAVYPFQLN
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: PSBB_ANGEV
Sequence: MGLPWYRVHTVVLNDPGRLLSVHLMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRIGITKSWGGWSITGDTVNDAGIWSYEGVAASHIVLSGLLFLAAIWHWVYWDLDLFRDERTGKPSLDLPKIFGIHLFLSGVLCFGFGAFHITGLFGPGIWVSDPYGLTGKVQPVDPAWGAEGFDPFVPGGIASHHIAAGILGILAGLFHLSVRPPQRLYKALRMGNVETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIDRRIRASKAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGAMDNGDGIAVGWLGHATFKDKEGHELFVRRMPTFFETFPVVLVDEEGVVRADVPFRRAESKYSVEQVGVTVEFYGGELDGVSFSDPATVKKYARRAQLGEIFEFDRATLKSDGVFRSSPRGWFTFGHATFALIFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSTB5_TRIV2
Sequence: MNQQLIPAIKVKDLSFYYNTSKAIEGISMDIYRNKVTAIIGPSGCGKSTFIKTLNRISELEGPVKVEGVVDFFGQNIYDPRININRLRRQIGMVFQRPNPFPMSIYENVAYGVRISAKLPQADLDEIVESALKGAALWQEVKDKLNKSALGLSGGQQQRLCIARALAIKPKVLLMDEPCSALDPIATMKVEELIHSLRSELTIAIVTHNMQQATRVSDFTAFFSTDESRIGQMVEFGVTTQIFSNPLDSRTRDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 5, ABC phosphate transporter 5, Phosphate-transporting ATPase 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSRP_MYCS2
Sequence: MTKKSASSNNKVVATNRKARHNYTILDTYEAGIVLMGTEVKSLREGQASLADAFATVDDGEIWLRNVHIAEYHHGTWTNHAPRRNRKLLLHRKQIDNLIGKIRDGNLTLVPLSIYFTDGKVKVELALARGKQAHDKRQDLARRDAQREVIRELGRRAKGKI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y3328_VIBCM
Sequence: MFDDLPTLTHAEQQVAVEKIQKLMAEGISTGEAIKIVAQQIREDKKAQNQGTH
What are the official names of this protein?
UPF0181 protein VCM66_A0528.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: LIGB_PSEF5
Sequence: MLPRAVVLLSLTPFFAQAACPDWPVPRATDEITALQQQLQRWDSSYYRDGRSLVADELYDQARQRLLTWRQCFPQAPRAMDQPLLGAGGSIRHPIPHTGVEKLADANAVTGWLKGRDDIWAQPKVDGVAVTLIYHRGQFQQALSRGDGVHGHDWTRAAWQIEAIPKRLPRPVDLLLQGELYLRLEQHVQARSGSLKARNRVAGWMARKQLTAAEAAQIGLFVWDWPQGPATLSERLEQLADLGFAEPREYSRPVGGFADAQQWRARWYRSPLPFASDGIILRQSRRPAAERWQAKAPYWIAAWKYPYAQVLASVRQVDFRIGRTGRITPLLEIEPVTLDDRQIRRVSLGSLQRWRSLDIVPGDQVAISLAGLSIPRLDEVVLRSTLRQSIQPPREADFHFLSCWQPSPGCEEQFLARLTWLSSKQGLNLQNIGSRTWARLVETGRIKGLLDWLTLDQAELANIAGFGDRSSKRLLESLHSARQQPFPRWLKALGIPPSGSADLSGPWQALAMKNSLDWQNEAGIGAERAAQLVAFFRAPEVLALQGALNSAGIEGF
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: YANE_SCHPO
Sequence: MKGCSFLRNGAKFQGKQKGVSSSTLEVHVTILHVNLAKSMLCGFIHVSYTSPNNTSLTTYFEAEIIGNRFTFETKWPEWGASEEIDNRHWKRLGALKSNGKDIPLRLIQPYDPLSRETVYMRWKELAMLDKTVDYQNHNQSFPFGISYEGFYYISFSQSTGKIKGYYYHHSEPEKVLFLELNPIIDRTFPVIEFQ
What are the official names of this protein?
Uncharacterized protein C3H1.14.
Protein: ISPH_CERS5
Sequence: MTKPPLTLYLAAPRGFCAGVDRAIKIVEMALEKWGAPVYVRHEIVHNKFVVDRLRDMGAVFVEELDEAPTDRPVIFSAHGVPKSVPAEAERRNMVYVDATCPLVSKVHLEAERHHENGLQMIMIGHAGHPETIGTMGQLPEGEVLLVETVEDVAGLEVRDPERLAYITQTTLSIDDTAAIVAALRERFPAINIPRKEDICYATTNRQGAVKALSDRIEALLVIGAPNSSNSRRLVEVGRAAGCRVAQLVQRATEIDWDSLQGVTAVGVAAGASAPEVLVDEVIAAFRERFDTTVELVETVKERVEFKVPRILREAAETP
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: QUEC_RICB8
Sequence: MKKAVILVSGGADSATVLAIMREQGYEIHAISFNYGQRNNAELRKVTELVKEYNVKQHKIVNIDLRAFGGSALTDDDIKVPHYHDTKELPEDVPVTYVPARNTIFLSYALGFAEIIGAKDIFIGVHTSDSANYPDCRPEYIKSFEAMANLATNIGGVTIHTPLINMTKDQIIKTGLRLGVDYKNTISCYDPSEDDLSCGTCLACTIRLDAFKKNNVQDPINYILF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RB33A_MOUSE
Sequence: MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFSQEANGKASCPC
What are the official names of this protein?
Ras-related protein Rab-33A, Small GTP-binding protein S10.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: YJHX_SALG2
Sequence: MNLSRQEQRTLHVLAKGGRITHIRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQPDNR
What are the official names of this protein?
UPF0386 protein YjhX.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: ENO1_HEVBR
Sequence: MAITIVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPSGASTGIYEALELRDGGSDYLGKGVSKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAVCKAGAHVKGIPLYEHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTGKVVIGMDVAASEFYGSDQTYDLNFKEENNNGSQKISGEALKDLYKSFVAEYPIVSIEDPFDQDDWAHYAKLTSEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTESIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLRIEEELGSEAVYAGANFRKPVEPY
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET2_LACTC
Sequence: MSEISDAEKRRILREKRQQKFNKGGASSRLAKITGQTENSFLSTESPLDSRESTYPAQETKAPAGNEDSTKQMDELLAKATSKTTSKASSPPGSAEQQNGNPELDLFAQIAKLQQNANNETVSTDPSGTPDIFAQLMASMQQDEAKGGSPGATAQQPIDPAIVEAHNIAVNKLKSYTILVKWLFFLLPYLYYITHSARDPFQHNAVNYVLDRSNFFTVFTTFEIVALSVYYQLLMSAEKSHNVNTLDNNSKILKLVSMVPPGLVPIPNLRGKVAQALQYWDVVSMYLTDLCFAIVLAGLFQYYHSM
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PDXS_THET8
Sequence: MEKGTFQIKTGFAEMFKGGVIMDVTTPEQAVIAEEAGAVAVMALERVPADIRAQGGVARMSDPKIIKEIMAAVSIPVMAKVRIGHFVEAMILEAIGVDFIDESEVLTPADEEHHIDKWKFKVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVVEAVRHARTMWKEIRYVQSLREDELMAYAKEIGAPFELVKWVHDHGRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSGIFKSGDPRKRARAIVRAVAHYNDPEVLAEVSEDLGEPMVGINLDQLKEEERLAKRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: TAG2C_AGEOR
Sequence: MKAIISLLLISAMVFSMIEAVPVEEGLQLFEGERGCLPHNRFCNALSGPRCCSGLKCKELSIWDSRCLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1c, U2-AGTX-Ao1c, Toxin-like structure Agel_02.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLND_SHIBS
Sequence: MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: WASF1_HUMAN
Sequence: MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE
What is the function of this protein?
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.  Promotes formation of actin filaments.  Part of the WAVE complex that regulates lamellipodia formation (PubMed:29961568).  The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).  As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).  Also involved in the regulation of mitochondrial dynamics (PubMed:29961568).
What are the official names of this protein?
Actin-binding protein WASF1, Protein WAVE-1, Verprolin homology domain-containing protein 1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
Protein: CDR_STAAW
Sequence: MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
What is the function of this protein?
Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
What are the official names of this protein?
Coenzyme A disulfide reductase, CoA-disulfide reductase, CoADR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
Protein: TRAX1_ECOLI
Sequence: MTTDNTNTTRNDSLVARTDTWLQSLLVWSPGQRDIIKTVALVLMVLDHANRILHLDQSWMFLAGRGAFPLFALVWGLNLSRHAHIRQLAINRLWGWAVFSQFWYYFAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILMMALWGPLSGTSYGIAGLLMLAVSHRLYRAEDRMERLVLVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKLLSRFWPGDFFPTFYACHLAVLGVLAL
What is the function of this protein?
Responsible for the N-terminal acetylation of F pilin.
What are the official names of this protein?
Protein TraX.
What is the protein family that this protein belongs to?
Belongs to the TraX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOZ_STAHJ
Sequence: MLNPPLNQLQSKINSKYLIATTAAKRARELDERPETALLSGYHSAKPVGEALEEIASGKITPVVSDEFTM
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ATP6_RHOPT
Sequence: MAADPIHQFQITKLFTLGHVGGQEIAFTNSSAYMFGTVALIAILMLVPGRQLVPGRLQSIAELSYEFVANMIRSTAGKEGLKFFPLVFSLFMFIAVSNLIGIVPYTFTVSSHLIVTVALALLVFFTVLIYGFSKNGLKFFKLFVPSGVPIYILPLVVFIEVISFFLKPVSHSVRLFANMLAGHIALKVFASFVAMLGALGVVGWFGAVLPLGLTIALTALELLVAFLQAYVFAILTCIYLNDAIHPGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPE_CUSRE
Sequence: MTLKLCVLTPNRIFWDSEVEEIILSTNSGQIGILPTHTPIATSVDIGILRIRLNGRWLTMALMGGFARIGNNEITVLVNDAERSSDIDPQEAQQTVEIAEANFRKAKGKRQKIEANIALCRARTRVKAVSPISVGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, plastid, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Peripheral membrane protein.
Protein: HRG_RAT
Sequence: MKVLTTALLLVTLQCSHALSPTNCDASKPLAEKVLDLINKGRRSGYTFQLLRVSDAHLDRVETATIYYLVLDVVESDCWVLSTKAQDECLPAMRTSEVVIGQCKVIATRYSNESQDLSVNGYNCTMRSVSSAYINTKDSPVLVDSFEDSEPYRKLARKALDKYKAENGDFASFRVERAERVIRMRGGERTSYFIEFSVRNCSTQHFPRHPPVFGLCRVVLTYSTEASDLETPEYTDLICEVFNTEDLKNRSDMKPHRGHEHPHCDKHLCKLSGPRDHHHTHKTHEIGCPPPPEGKDNSDRPPLQEGALPQMLPGHSGPSGTNRSHRPPHNHSCNEHPCHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGHHPHGDHPHGHHPHGHDFLDYGPCDPPSNSQELKGQYHRGHGPPHGHSRKRGPGKGLFPFHQRQIGYVYRLPPLNVGEVLTPPEANFPIFSLPNCNRPPQPEIRPFPQTASKSCPGKFEGKFPQVSNFFEHTPPK
What is the function of this protein?
Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions.  Inhibits rosette formation.  Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis.  Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway.  This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions.  Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes.  Tethers plasminogen to the cell surface.  Binds T-cells and alters the cell morphology.  Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2 (By similarity).
What are the official names of this protein?
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG, Histidine-rich glycoprotein 1, HRG1.
What are the subcellular locations of this protein?
Secreted.