PharMolix/UniProtQA huggingface dataset:
Protein: Y4TQ_SINFN
Sequence: MALTTSRASGSPRIQTHTVVRIAKRHPLVLLGGGILLLLILLALAAPLYSGDPLVMDPFKRLQQPSASMWFGTDNLGRDVFARTIYGARISLIVGLLSAVCAAVCGLLIGVIAGYSRTFDNIIMRVMDGLMSIPTFLLAIALLSLTGPGIGILIVAIAIPETPAVTRLVRSVVLSVRSRPYVEAALCGGARLPRVLWRHILPSTIPPLMVQSATVCASAIMTEAGLSFIGVGVPSEIPSWGNMIANSRLFLAIAPLTIFAPGLCLAVTVLAVNLLGDGLRDMFDPRSKRRR
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable peptide ABC transporter permease protein y4tQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_CORJK
Sequence: MRPAKPPQSKERKRSKSLTSADHDNSPQRAETAASALRQRIRVVPDFPSRGIVFEDLTPVLADPHSFKLLVQDLANHCRNFDIDLIGGLDARGFLLGSAVAYELGVGILAVRKGGKLPPPVHHVDYSLEYGTASLEIPADNAIPLQGKNVFLIDDVLATGGTLSASRELLENAGANVCGLGVVLEVSALDGRDRLKDLPLYVVDQAG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_VIBVU
Sequence: MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEALVVKMTQQFAIDLVVIACNTASTIVLPTLRAKLPIPVVGVVPAIKPASLLANRAVGLIATPATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGRQVDQQELAMILKPMKHKVDVAVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQPWDEAALNGSLKTMGFNAIELYPL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RIMK_SALTY
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: EFL3_CAEEL
Sequence: MTTIFGSSNAMFLNIEANKENIPPGTEFKKESFVLPEPRVNRTTDPDHENLLPSPVPRPSPAMSQLSDASFLSQDGGAVNTSADEADDDLEVTSRKEKSLGLLCQRFLIAINEETVGSSTREVHLETVARKMNVEKRRIYDIVNVMEALDAMQKTNKSYYQWQGLESLPKLMFDLQNEAVEEGLPERVLRVEQAMCSFTELSSPRGKQGFKDIVGSFVSCTSTPTTPSTSFDSVTVKMEPAGLLEKRSRVDTRDRQGRNSLAQLCRRFLMVLLSNPKNIRKVSLDVASTVLIKDPETEGFEPPSRSRCRRLYDIANVLVALGLIKKVHYLFGTKKIPLFVYCGPEPDQTGSFDVFQSVERLLSSSQNVPQTPIIKAQTDKIVQQIAGFGKRTLSEQNLTKPSGNTPKIAKIKSAAVRSSPMYMENNLFMFAEVVTAEAAAEKMRYDAFAQLSRTILGSVASINSLNAPLTSSQHPMTSRLPPLPMAPLQLPKLPEIPKPQAQKQFTFPATSRPRFNFPDYTPVQSTIRPLVSQMTFPQESSQLHNLDVKPKHLMSNILGESKKFKNNQNTFEHTTSSAFQVVKKGETRPKKVFGEIQNLQ
What is the function of this protein?
Probable transcription factor which represses gene expression in a subset of ventral nerve cord neurons (PubMed:21596899).  Involved in regulating programmed cell death and determining cell fate during development, acting in a partially redundant manner with lin-39 to repress the BH3 domain-encoding gene egl-1 in the VA and VB motor neurons (PubMed:21596899).
What are the official names of this protein?
Transcription factor efl-3, E2F-like family member 3.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: REEP6_HUMAN
Sequence: MDGLRQRVEHFLEQRNLVTEVLGALEAKTGVEKRYLAAGAVTLLSLYLLFGYGASLLCNLIGFVYPAYASIKAIESPSKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQVLARSRAGITPVAVAGPSTPLEADLKPSQTPQPKDK
What is the function of this protein?
Required for correct function and survival of retinal photoreceptors (PubMed:27889058).  Required for retinal development (By similarity).  In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity).  May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).
What are the official names of this protein?
Receptor expression-enhancing protein 6, Polyposis locus protein 1-like 1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein.
Protein: AGD4_ARATH
Sequence: MATFINLEDSPMFQKQVCSLEGTADELKDRCQKLYKGVKKFMGTLGEASKGESAFAACLEEFGGGPDDPISLSIGGPVISKFINALRELASYKEFLCSQVEHVLLERLMNFISVDLQEAKESRHRFDKAAHSYDQSREKFVSLKKNTRGEIVAELEEDLENSKSTFEKSRFNLVNSLMTIEAKKKYEFLESISAIMDAHLRYFKLGYDLLNQLEPFIHQILTYAQQSKEQSKIEQDRLARRIQEFRTQSELDSQQLVANAESSGANGNRVGGNIPYKNTETSLTADKEVIKQGYLLKRSSSLRTDWKRKFFVLDSHGSMYYYRTNGNKSMGSHHHYSGSSDHNTGVFGRFRARHNRSGSLTEGSLGYNTIDLRTSLIKLDAEDMDLRLCFRIISPQKTYTLQAENGADRMDWVNKITKAIGTLLNSHFLQQSPVRYLDKDNSSSAPANAVVSGDQIRHNDSRQNIGDDVSTILRGLPGNNACAECNAPEPDWASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLDVKVWEPTILDLFRNLGNVYCNSLWEGLLHLDDDCEDGSALSHASVSKPCPEDSFSVKEKYILGKYLEKALVIKDESEANLSAASRIWEAVQSRNIREIYRLIVTTGDVNIINTKFDDITDIDAYHHIDAAEKAVKKRHDPTVCQRIKESNEPRSCLQGCSLLHVACHIGDSVLLELLLQFGADLNIRDYHGRTPLHHCISSGNHKFAKILLRRGARPSIEDDGGLSVLERAMEMGAITDEELFLLLAECA
What is the function of this protein?
Probable GTPase-activating protein.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein AGD4, ARF GAP AGD4, GCN4-complementing protein 1, Protein ARF-GAP DOMAIN 4, AtAGD4.
Protein: APF9_GIBF5
Sequence: MKPHTVSLVLSNLASLAAATCKCTPGHACWPSLEEWSRFNSSIGGQLIQSSPVAEACYSGPKDNAACQNIEKSWTDDVFQVSQPIGYAWPLNLSCPLPTPGLDTKCSIGNSPVYVVNVTCEEDITRGIKFAQEKNLRLVVKSTGHDSQQRSTGYGSLSIWLHNFRKGFRFQGHNPVLATCPKSGWKGSTLTINGGYSWRDIYPAAQKQGLIVIGGLDRGPCSTGGWTQGGGHSPGTHYFGIGADQVLSARVVLASGKIVVASPCENEDLFFAIRGGGGGTFGVVTEITVKTYPTKALSTINLIVGSKGDETVPKFLDAVATIYSLLPGLSKKGFAGYGNWVVRALSPITAKNYTNLYGQSWTLLGATQQEAENLFQPFKEEIVKHQSENGLEVTVSSGTFRDYFSYYYSMGNGTDSAVGGVSALASRLLDTEALQGNRKDLRKFLDSITQGSAVYHTLIHHGLEAAADVKADPTSAVLPGWYKSILLDEFEIPMNTTDVDAYAGSFEYLRNELVPLYESLSPDTGTYMNEADWGNMNWKKDFFGSHWDRLLKVKTRYDPEGFFYCPKCVGSDDWVENKGGSLCRA
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the cyclic tetrapeptide apicidin F (APF) (PubMed:25058475).  The non-ribosomal peptide synthetase apf1 incorporates four different amino acids to produce apicidin F: L-phenylalanine, D-pipecolic acid (D-pip), N-methoxy-L-tryptophan and L-2-aminooctanedioic acid (PubMed:25058475).  L-Phenylalanine is the only proteinogenic amino acid directly used by apf1 (PubMed:24195442, PubMed:25058475).  The 3 other apf1 substrates are non-proteinogenic and have to be modified by other enzymes of the cluster (PubMed:25058475).  Lysine is converted to delta-1-pyrroline-5-carboxylate (P5C) which is reduced to L-pipecolic acid (L-pip) by apf3 (PubMed:25058475).  L-pip is epimerized to D-pip, probably by apf1 activity, prior to incorporation (PubMed:25058475).  L-Tryptophan is N-oxidyzed by one of the cytochrome P450 monooxygenases (apf7 or apf8), and further methylated at the hydroxy group by the O-methyltransferase apf6 to yield N-methoxy-L-tryptophan (PubMed:25058475).  The synthesis of the fourth apf1 substrate is more complex (PubMed:25058475).  The fatty acid synthase apf5 is involved in the synthesis of the octanoic acid backbone of L-2-aminooctanedioic acid by fixing one acetyl-CoA unit and three malonyl-CoA units (PubMed:25058475).  Then one of the cytochrome P450 monooxygenases (apf7 or apf8) may oxidize this backbone to 2-oxooctanoic acid (PubMed:25058475).  The aminotransferase apf4 is predicted to catalyze the exchange of the keto group with an amino group (PubMed:25058475).  The next step would be the oxidation of 2-aminooctanoic acid by one of the cytochrome P450 monooxygenases (apf7 or apf8).  The last step is the oxidation of 2-amino-8-hydroxyoctanoic acid to 2-aminooctanedioic acid is catalyzed by the FAD-dependent monooxygenase apf9 (PubMed:25058475).
What are the official names of this protein?
FAD-linked oxidoreductase apf9, Apicidin F synthesis protein 9.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: ENO_BACFN
Sequence: MKIEKITGREILDSRGNPTVEVDVVLESGIMGRASVPSGASTGEHEALELRDGDKHRYGGKGVQKAVENVNKVIAPHLIGMSALDQIGIDHAMLALDGTKTKAKLGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVLPVPMMNIINGGSHSDAPIAFQEFMIRPVGASSFKEGLRMGAEVFHALKKVLKDRGLSTAVGDEGGFAPNLEGTEDALNSILAAIKAAGYEPGKDVMIGMDCASSEFYHDGIYDYTKFEGEKGKKRTADEQIDYLEKLINEYPIDSIEDGMSENDWEGWKKLTQRIGDRCQLVGDDLFVTNVDFLAKGIEKGCANSILIKVNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSDRMAKYNQLLRIEEELGDRAVYGYKRIVVKG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DPO1_ECOLI
Sequence: MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.  It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: NDK1_PEA
Sequence: MAEQTFIMIKPDGVQRGLVGEIISRFEKKGFYLKGLKFVNVERAFAEKHYADLSAKPFFSGLVDYIISGPVVAMIWEGKNVVTTGRKIIGATNPAQSEPGTIRGDFAIDIGRNVIHGSDAVESANKEIALWFPEGAANWESSLHSWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  This NDK is microtubule-associated.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: PDE6D_DROMO
Sequence: MGSDDLSAGDKIQKGFQINYMILRDADTGKVIWQENKDFSAPDVEHEARVPVKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNEILITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: VATA_THEPD
Sequence: MSGQRKGYIAKVSGPVVIAKGISDIKMGEVVYVGNEGLLGEVVRVSQDSFAVQVYEDTSGLRPKEPVTATGKLLVAELGPGLMGRVFDGVQRPLKSIEELVGPFVKRGVKVNPLPRNVKWHFKPSVKVGDKVSSGDIIGVVQETPLIEHRVMVPIGVSGKVKEVVPEGDYTVEDPVVILESDGRVVELTMKQEWPVRQPRPYKERLPSEVPLLIGQRIIDTFFPIAKGGAGAIPGGFGTGKTVTLHKVSMYSDSQIVVYIGCGERGNEIAEMLKEFPVLVDPKSGRPIIERSIIIANTSNMPVSAREASIYMGVTIAEYYRDQGYDVTLIADSTSRWAEALREIAGRLGELPVERGYPAYLPDKIAEFYERGGRVKALGSPERSGSVTVLGAVSPPGGDYNEPVTIHTLRFVGTMWALDTDLAYRRHFPAINWLKSFSQYADIIERWWVKNVSPEFPKYRRRALRLLTVASEIEAIASVVGEGALPDDQRLILLTSEIIKEGFLRQTALSGEDVFCKPEKQYWLLKMMMDFFDKSYELIRKRVSIEEILRMPEIYEMMRVKEDERGLQAVKELYERVMAKLDEIAQRHGVTLAVEAEEVVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: MNME_PSEPK
Sequence: MNTVRETIAAIATAQGRGGVGIVRLSGPLAAKAGLLITGRTLTPRHAHYGPFRDDEGLVLDEGIALFFPGPNSFTGEDVLELQGHGGPVVLDMLLQRCVQVGCRLARPGEFSERAFLNDKLDLAQAEAIADLIEASSSQAARNALRSLQGEFSRRVHSLTEALIALRIYVEAAIDFPEEEIDFLADGHVLSMLDAVRSELSTVQREAGQGALLRDGMTVVIAGRPNAGKSSLLNQLAGREAAIVTDIAGTTRDILREHIHIDGMPLHVVDTAGLRDTDDHVEKIGVERALKAIGEADRVLLVVDSTAPEASDPFALWPEFLAQRPDPAKVTLIRNKADLSGERVALEQCDDGHVTITLSAKGDDTGLQLLRDHLKGCMGYEQTAESGFSARRRHLDALRQASEHLEHGRAQLTLAGAGELLAEDLRQAQHALGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_CHLPN
Sequence: MLKHDTIAAIATPPGEGSIAVVRLSGPQAIVIADRIFSGSVASFASHTIHLGQVIFEETLIDQALLLLMRSPRSFTGEDVVEFQCHGGFFACSQILDALIALGARPALPGEFSQRAFLNGKIDLVQAEAIQNLIVAENIDAFRIAQTHFQGNFSKKIQEIHTLIIEALAFLEVLADFPEEEQPDLLVPQEKIQNALHIVEDFISSFDEGQRLAQGTSLILAGKPNVGKSSLLNALLQKNRAIVTHIPGTTRDILEEQWLLQGKRIRLLDTAGQRTTDNDIEKEGIERALSAMEEADGILWVIDATQPLEDLPKILFTKPSFLLWNKADLTPPPFLDTSLPQFAISAKTGEGLTQVKQALIQWMQKQEAGKTSKVFLVSSRHHMILQEVARCLKEAQQNLYLQPPEIIALELREALHSIGMLSGKEVTESILGEIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM4_METTH
Sequence: MAVTRPPERSAEAVELIEGAGGRALVAPTLELKEAHTESLREVCRRADEWDLVIFTSQAAVESLFQLCREFAGKIRKDCLVAVIGPRTARVAGEHGLRVDIVPEDYTAEGLLDALTGLNIEGWKVALPRTLSARKVLPRGLEMMGAEVLVAEAYRSGLPEDTGPAEELIDGLLDGKVDAVTFTSPLTVENLFKIAGNRRKELIEVLKRVKVAAIGPITLRKLEEHGITAVTPERYTVKDMIAALAVSMGEDVD
What is the function of this protein?
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
What are the official names of this protein?
Putative uroporphyrinogen-III synthase, UROS, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen-III synthase family.
Protein: PPR42_XENLA
Sequence: MVRLTVDLVMKNSNVLRNRKDESLARHLRRITHLNFSNKNIDEVEDLTMCRNLTVLYLYDNNINQIKNLGSNLTHLYLQNNCISCIENLSGLKRLEKLYLGGNCLTVVEGLEGLRELRELHIENQRLPPGEKLLFDPRTLHFLGISLSVLNISNNNIDELKDLAVLENLTQFVAADNQLKEIKDLEFVLSKWTKLCRMDLSGNPVCLKPKYREKVTIISKTLEILDGKEIKEMARQFLLNWKASRISKKKKNLENMTGPSLLPQLYESDNYRSLLPVYNQNFRHQLLEQPKYIVMAHTQSCNKHGQLQRSAGKRNISVIEDIKSEARGMESFSGCIPESECVGGQHGNERPGYPTNLINLWKGEKDETEGIP
What is the function of this protein?
May regulate phosphatase activity of protein phosphatase 1 (PP1) complexes.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 42, Leucine-rich repeat-containing protein 67.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: ERG6_MAGOY
Sequence: MSKQQHPSSKTQITRRRDTADMTFEQVLHKGSSANMGGLSSMLGKDREASKTAVDQYFRHWDGKTAKTETTKVREERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPGETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVERARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLKPGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESEDLADNSDRAPWYWPLGGNAWQYASTFGDILSTFTMTPAGRAIAHTVLGVVESIGLVPPGTKKTADSLSTTAAALVAGGKEGLFTPMFLMVARKPVAKE
What is the function of this protein?
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.
What are the official names of this protein?
Sterol 24-C-methyltransferase, Delta(24)-sterol C-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Protein: CHLL_GLOVI
Sequence: MKLAVYGKGGIGKSTTSCNISVALAKRGRRVLQIGCDPKHDSTFTLTGFLIPTIIDTLEEKDYHYEDVYAEDVIYEGYGGVHCVEAGGPPAGAGCGGYVVGETMKLLKELRAFEDHDVILFDVLGDVVCGGFAAPLNYADYCVIITDNGFDALFAANRIAASCREKARTHPLKLAGLVGNRTNKRDLIDKYVEAVPMPVLEILPLIEDIRVSRVKGKTIFEMAETDPSLEPVCQYYLNIADHLLACPEGVVPQECPDRALFELLSDFYSRTPVPA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: EIF3C_DROPE
Sequence: MSRFFANGSDSESESSEEEVQAPNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYTKALPVISKEENGITPRFYIRCLAELEDFINEIWEDREGRRNLSKNNTKSLGTLRQKVRKYIKDFEEDLSRFREAPDQESEAEDEEAHVSDAGEAADDSYAGFKKEASVTAPKIAKSAPAKSVPADDEDSDDSIDWDSDSESETESSEDENQYQNMRERFLKRSTEKGEDKGDDDKRKDKRKEQKLKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDIPLVLAKLVEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGVPVSVKIHFNIISAIFDYNQKISEPMKMEHWALLLEVMQSMMKLLLANADISISESVAEEHEEYITAPFYIRGCPLAAVERLDDEFTKLLKECDPHSNDYVSRLKDEMNVVKTIELVLQYFEQCGNPNERCRIYLRKIEHLYYKFDPEVLKKKRGEVPATTATSVDVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQENVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLVKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWGGQRRDNRNQRNRNQRGHHKNQQQQQQQQVQTIDEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_RHIL3
Sequence: MKPAKSSPVQIARRGLMLVISSPSGAGKSTIARTLLETDRQIGLSVSVTTRQRRPSEVEDVHYHFKSVREFERLRDSDALLEWAEVHGNFYGTPREPVEQAMGEGRDMLFDIDWQGAQQLQEKMSADVVSIFVLPPTMTELQSRLHRRAEDSEEVIQTRLANSRAEIAHWREYDYVIVNDDLNAALDAVQSIVKAERLRRDRRHGMFDFVRELLEETPSL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_IDILO
Sequence: MPKKDALDHLSLGQHTDYPNEYDPKQLQPVPRSLNREPIGLKDKLPFSGVDLWTGYEISWLNANGLPQVAVGYFAVPAESPNLIESKSFKLYLNSFNDSRFDTWEYVQQLMETDLSACAGTPVKVKLKQLSELEGESVATFPGHCIDDQNISISHYDYQPSLLATEQHETEEALHSHLLKSNCLITNQPDWGSVYIHYQGPKLDRAALLAYLVSFRRHNEFHEQCVERIYQDLKALGMKKLTVYARYTRRGGLDINPFRSDFEPALQMQRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS905_HUMAN
Sequence: MGFHHVGQAGLELLTSGHPALERRPEYLEERRIKEIVKKHSQFIGYPITLFVEKKRNKQVSDAEAEKKEDKRKKKKESNDKPEIEDVGSDEEEEKKDADKKKKKSKEKYIDQELNKTKPIWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEGQLEELKDSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVSNCMEDPQRHTNKIYRMIKLGLGVDEYDPTANDINAAITKEMPPLRGGDDTSRMEEVGGSG
What is the function of this protein?
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
What are the official names of this protein?
Putative heat shock protein HSP 90-alpha A5, Heat shock protein 90-alpha E, Heat shock protein 90Ae.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_ECOL6
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFELQYKKSLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYSTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.