PharMolix/UniProtQA huggingface dataset:
Protein: GLGX_MYCTU
Sequence: MSSNNAGESDGTGPALPTVWPGNAYPLGATYDGAGTNFSLFSEIAEKVELCLIDEDGVESRIPLDEVDGYVWHAYLPNITPGQRYGFRVHGPFDPAAGHRCDPSKLLLDPYGKSFHGDFTFGQALYSYDVNAVDPDSTPPMVDSLGHTMTSVVINPFFDWAYDRSPRTPYHETVIYEAHVKGMTQTHPSIPPELRGTYAGLAHPVIIDHLNELNVTAVELMPVHQFLHDSRLLDLGLRNYWGYNTFGFFAPHHQYASTRQAGSAVAEFKTMVRSLHEAGIEVILDVVYNHTAEGNHLGPTINFRGIDNTAYYRLMDHDLRFYKDFTGTGNSLNARHPHTLQLIMDSLRYWVIEMHVDGFRFDLASTLARELHDVDRLSAFFDLVQQDPVVSQVKLIAEPWDVGEGGYQVGNFPGLWTEWNGKYRDTVRDYWRGEPATLGEFASRLTGSSDLYEATGRRPSASINFVTAHDGFTLNDLVSYNDKHNEANGENNRDGESYNRSWNCGVEGPTDDPDILALRARQMRNMWATLMVSQGTPMIAHGDEIGRTQYGNNNVYCQDSELSWMDWSLVDKNADLLAFARKATTLRKNHKVFRRRRFFEGEPIRSGDEVRDIAWLTPSGREMTHEDWGRGFDRCVAVFLNGEAITAPDARGERVVDDSFLLCFNAHDHDVEFVMPHDGYAQQWTGELDTNDPVGDIDLTVTATDTFSVPARSLLVLRKTL
What are the official names of this protein?
Glycogen operon protein GlgX homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: VATC_HALWD
Sequence: MSVSGSNPEYVTARVKARESALYDDEEYRKLVRMTPAEIARLMEESDYEREINALGSRYSGVDLIEYALNQNLARQFDDLLRWANGRLYDLIARYLRKFDAWNVKTVIRGIYSGTESDTVNDDLIRAGEFSDELLDTLLDAGSIEEAVERLSAAGTIYGSELESAYDDYDESGVLIPLENAVDRTYYEQLLADLTVDEATAQYREFLEAEIDFRNAQNAFRLAQSGADIDPAAYYIDGGSLFTATELATFAQNRNELIEAIRESRYGDDLSEALNQIETADSLIQFERALDNALLEYSDTLGTVHPLSVTPVVSYILAKEREVDNIRAIARGREAGLSDDEIKQEFM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: PDRP_BRUA4
Sequence: MTRPLSYFHLHLISDATGETLLAAGRAAAAQYANARAIEHIYPLIRTEKQLRKVLEGIDAEPGIVLYTIVDQKLAAIIDDSCAEMGVPSVSVLEPVLNTFQSYLGAPAHRRASAQHVLNADYFRRIDALNFTMEHDDGQLPYDIEEADVILVGISRTSKTPTSIYLANRGIKATNVPIVLGIPLPEVLFTAKRPLIVGLVATAERISQIRQNRPLGNVPSLDTGLYTDRVSISEELAYARNICNRNGWPIIDVSRRSIEETAAAILALLRAHNEKG
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: KCY_METM6
Sequence: MIITIGGLPGTGTTTTSKLLSEKYGLNHVCAGFIFRDMAKEMNMTLQEFSSYAETNTEVDNEIDRRQVEAAQSGDLILEGRLAGWILKKSNIKPDLSIWLKADPMVRCIRISERENENVDLALEKMISREASEKKRYKEIYNIEIDDLSIYDIVIESSKWDANGVFNIIEKAIENLKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DU4L4_HUMAN
Sequence: MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGEAPPPQPAPPDASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPLLETEAPGELEASEEAASLEAPLSEEEYRALLEEL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Double homeobox protein 4-like protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_YERPE
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVAGLFMKNWEEDDDEEYCSAATDLADAQAVCDKLGMELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRQDVDGKSRLLRGLDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPEVRRIAEQLDLVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIMTVDGQLVGKHQGLMYHTLGQRKGLGIGGTKEGGDDPWYVVDKDLDSNTLLVAQGHEHPRLMSVGLVAQQLHWVDRQPVTAPFRCVVKTRYRQQDIPCTVTPLDDERVDVRFDDPVAAVTPGQSAVFYQGEICLGGGIIEQRYPLTNPA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4E_KORCO
Sequence: MGKMGGSRHLKSLAAPGYYPIAKRERVWVVKPSPGPHAIDEGIPLLLIVRDMLKLATTAREARRIISMKKILVDGKPRYDYKFQVGLMDVISIPEIGVNYRMVPDPHRFLRLIEIPQSESKMKLVKVIGKRTIRGGRIQLTSHDGRNFLLDGRDVKPGDSLLIELPSQSVIDHLRFDTGSSVLVTRGRMAGRIGRVEGIGTIIEMRDLENPELSYRGVKENLIVVGKERPVLKLR
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: FAEC_ASPOR
Sequence: MIKSIILQAIMVLSTLTSVHGANSSGCGKQPTLVNGVHKINDREYILKVPDNYNANKPHHLIFGLHWRGGNMNSVVNGESVEPWYGLETRAQGSAILVAPNGRNAGWANINGEDVALIDAIIKQVEDDLCIDQSSRFATGFSWGGGMSYALACARAKEFRAVSVLSGGVISGCEGGHDPIAYLGIHGISDPVLPFDGGVTLANKFAANNGCQQTYVGKPGLGSHSSVQTDFKGCSRPVSFIAYDGGHDAAPLGVGNPLAPDATWKFFMAA
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin.  Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan (By similarity).
What are the official names of this protein?
Probable feruloyl esterase C, Ferulic acid esterase C.
What is the protein family that this protein belongs to?
Belongs to the faeC family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_ACIB3
Sequence: MLTYPNIDPVAIHLGPLQVHWYGLMYLLAFLCAWGLASYRAKQRDGWTSDMVSDLVFYGALGVVLGGRIGYVLFYEFDKFLENPIWLFQVWTGGMSFHGGFLGVMIAMLFWCKKYQKTWFQTLDFVAPCVPTGLMFGRIGNFIGGELYGRAVTDPNYPFGMIFPTDPLHLVRHPSQIYQALCEGLLLFIILWWFSSKPRPRMAVSALFLMGYGVARFVMEFFRQPDADQGFILFGWMTKGQILTVPMLLIGLWMMWYAYQKKIYDWGPQKNS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_KINRD
Sequence: MSRTPLIAGNWKMVLDHQQGTLLVQKLDWTLKDAKHDYSAVEVAVLPSHTSLRTVQTLIEGDKLSIALGAQDVSEHDSGAYTGEVSAAMLAKLGVTYVAVGHSERRQYHGETDATVRAKAAKALAAGLTPIVCVGEALEIRKAEQHVEFTVGQVTQALTGLTAEQAAGLVLAYEPVWAIGTGEVATPEDAQEVCAALREAVAELFDRATADAVRVLYGGSVKPASIAAIMRQPDVDGALVGGASTDAGDFAAIVRFRDHPA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA5_RAT
Sequence: MAAVITWALALLSVFATVQARKSFWEYFGQNSQGKGMMGQQQKLAQESLKGSLEQDLYNMNNFLEKLGPLREPGKEPPRLAQDPEGIRKQLQQELEEVSTRLEPYMAAKHQQVGWNLEGLRQQLKPYTVELMEQVGLSVQDLQEQLRMVGKGTKAQLLGGVDEAMSLLQDMQSRVLHHTDRVKELFHPYAERLVTGIGHHVQELHRSVAPHAVASPARLSRCVQTLSHKLTRKAKDLHTSIQRNLDQLRDELSTFIRVSTDGADNRDSLDPQALSDEVRQRLQAFRHDTYLQIAAFTQAIDQETEEIQHQLAPPPPSHSAFAPELGHSDSNKALSRLQSRLDDLWEDIAYGLHDQGHSQNNPEGHSG
What is the function of this protein?
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL (By similarity).  May also be associated with chylomicrons (By similarity).  Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity).  Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity).  Binds heparin (By similarity).
What are the official names of this protein?
Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, Regeneration-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Early endosome. Late endosome. Golgi apparatus, trans-Golgi network. Note=In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network.
Protein: NUOD_METPP
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLILELDGEVIQRADPHIGLLHRATEKLAESKTYIQSLPYMDRLDYVSMMCNEHAYCLAIEKLLGVDVPVRAQYIRVMFSEITRILNHLLWIGAHGLDCGAMNILIYAFREREDLFDMYEAVSGARMHAAYFRPGGVYRDLPDTMPQYRVSKIRNAKALAKMNENRQGSLLDFIEDFCRRFPKNVDDYETLLTDNRIWKQRTVGIGVVTPERALNLGFTGPMLRGSGIAWDLRKTQPYDVYDRVDFDIPVGAGGDCYDRYLVRVEELRQSNRIIQQCAAWLRANPGPVITDNHKVAAPGRVDMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLAAMDEMSRGHMIADAVAVIGTMDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VP2_ROTW3
Sequence: MAYRKRGARREANINNNDRMQEKDDEKQDQNNRMQLSDKVLSKKEEVVTDNQEEIKIADEVKKSTKEESKQLLEVLKTKEEHQKEIQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKLFRIFEPRQLPIYRANGEKELRNRWYWKLKKDTLPDGDYDVREYFLNLYDQVLTEMPDYLLLKDMAVENKNSRDAGKVVDSETASICDAIFQDEETEGAVRRFIAEMRQRVQADRNVVNYPSILHPIDYAFNEYFLQHQLVEPLNNDIIFNYIPERIRNDVNYILNMDRNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKELVSTEAQIQKMSQDLQLEALTIQSETQFLTGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVVPNDMFIRESLVACQLAIVNTIIYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFVNNNQFRQVVIDGVLNQVLNDNIRDGHVINQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLAYNYETLMACVTMNMQHVQTLTTEKLQLTSVTSLCMLIGNATVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAANRLNLYQKKMKAIVEDFLKRLHIFDVARVPDDQMYRLRDRLRLLPVEVRRLDIFNLILMNMDQIERASDKIAQGVIIAYRDMQLERDEMYGYVNIARNLDGFQQINLEELMRTGDYAQITNMLLNNQPVALVGALPFVTDSSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWVPTSTTKVYKQVPQQFDFRNSMHMLTSNLTFTVYSDLLAFVSADTVEPINAVAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HUTU_BACCR
Sequence: MEKVQQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFDGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALTVANEYKEKREPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLAMQEKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVETAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STRP7
Sequence: MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQGVKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVAVENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIEGNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIAVLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVESRQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_CUPPJ
Sequence: MSDDKRAKPEKSKYPVNLLDTTFPMRGDLPKREPQWVKQWQDKQLYKKIRAARKGAKKFVLHDGPPYANGDIHIGHAVNKVLKDMIVKARGLSGLDAVYVPGWDCHGMPIEIQIEKQFGKGLPVQEVQAKARAYATEQIKRQMVDFERLGVLGDWGHPYLTMNYSNEADELRALGKIMEKGYVFRGLKPVNWCFDCGSALAEAEVEYKDKVDLSIDVGFPFAETDKLAHAFKLSIEQLNAKPGWIVIWTTTPWTIPSNQALNVHPEVEYALVDTPRGYLILATERVEEQLKIYELEGKVVATTTGAALSEIRFHHPLAKMDTGYDRLSPIYLGDYVTTDTGSGIVHSAPAYGVEDFQSCKAHGMSDHDIISPVMGNGVYAGTLPLFGGLSIWDANPKIVEVLKASGNLFNSHKYTHSYMHCWRHKTPIIYRATSQWFAGMDVDPVEQDGKAVPTLRETALAGIEATEFYPSWGKQRLHNMIANRPDWTLSRQRQWGVPMAFFVHKETGALHPRTAELLEEVARRVEQHGIEAWQTLDPKDLLGDEADQYEKNRDTLDVWFDSGTTHWTVIRGSHRDDLYDPSADEADGRLADLYLEGSDQHRGWFHSSLLTASMLYGKPPYKALLTHGFTVDGEGRKMSKSVGNTVSPQDIANKMGAEIIRLWVASTDYSGELSISDEILKRVVESYRRIRNTLRFLLSNLSDYDHSKHALPASEWLEIDRYAVALTERLQKEVLSHYDSYEFHPVVAKLQTFCSEDLGGFYLDVLKDRLYTTAADSKARRAAQNALYHITQAMLHWMAPFLSFTAEEAWQVFAHGTGHTDTIFTSTYYTLPEVDQADDLLQKWHSLREVRAEVTKQLEAVRVEGAIGSSLQAEVNIQAGGPVLAALQSLEDDLRFVLLTSAATVTPAPEAGDLLVTVTASTHAKCERCWHYRADVGQNPDHPTLCGRCDSNLFGAGEHRSHA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METVS
Sequence: MNILRRGRLGSSVKEDVMKFTTSLEFDKEIFQSDILCDIAHTTMLMEQKIVSIEFGEKVIEELKKIAKVGMDSLNLDPSLDDIHMVIESELIKKLGEDVAGRMHTGRSRNDEVATDLRLSLRKKVLEIVKLLIDMEENMLSLAKEHSETITVGYTHLQQAQPVTFGHQILSHVSAVERDISRFFDAYNRINISPLGCGAMATTGFNIDRKRTMELLGFYELIENSMDGVSSRDFIVETMANISMLGTNLSKICEELILFSTAEFKTVEIADEYTSTSSIMPQKKNPDVAEIARAKLSTLNGNLITVLTIMKALPNTYNRDLQEISPHLWKSTYTIIDCIKMIDGMVSTIKVNKERMKENAEKNYATATELADTLVRECNIAFRMAHGIVGELVRTSIEEKVEIKDIILDVFKANGLHLSKEKIDSALDPYENVKLRDVIGGPAPKEVERAVLSFKNKMELHSKNLNDKMRSIEAVEENLLN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBGP_ECOLI
Sequence: MTFIKGLPLMLLTISLGCNAAVQPDRTRIVFNANDKATSLRIENQSDKLPYLAYSWIENEKGEKSDALLVALPPIQRLEPKATSQVRVVKQASTTQLPGDRETLFFYNMREIPPAPDKSSDHAILQVAIQSRIKLFWRPAALRKKAGEKVELQLQVSQQGNQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGSYSGSQFYLGYMDDYGALRMTTLNCSGQCRLQAVEAK
What is the function of this protein?
Could be required for the biogenesis of the putative YbgD fimbria.
What are the official names of this protein?
Uncharacterized fimbrial chaperone YbgP.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NIS1_YEAST
Sequence: METYETSIGTQSYPPTLFPPPLGTGGFTTSGYIHALVDSTSNSNSNSNTNSNTNSNTNSNSDTKIPIVQISDDSHITHDSFKPYMEYHDASHLRNRNISKADQVESTEVMEQFTQWSNYKMRSRSPTINAKPIRHTSQRRTDFTSKNELSKFSKNHNFIFHKGFLKRQHSIRREDRQAKVRSRFRSKKELTSVLNYIELEQMDIANVLASQPVNLHAIRNLTSRDPAVTPIPFLRSQMYATSSRPPYLRNRSISRKLPKSQPGSLPTTMPATATKTIKQNSTTPTTRSVYNKNVGRSNTSPSVLYHPKRRGKLNTKSHARKEQLLLELWREYLMLVITQRTQLRLTLLCSPGSASNESSVCSSNASDLDMSLLSTPSSLFQMAGETKSNPIIIPDSQDDSILSSDPF
What is the function of this protein?
May be involved in a mitotic signaling network.  Binds sumoylated proteins and may stabilize SUMO chains.
What are the official names of this protein?
Protein NIS1, Jumonji domain-interacting protein 1, Neck protein interacting with septins protein 1.
What are the subcellular locations of this protein?
Bud neck. Cytoplasm, cell cortex.
Protein: SEC11_PLAF7
Sequence: MDFIKEQYNSLVLDLRKTFRNKRDGLSHILNVICLLLNALMIWKLLVVFTGCESPVVVVLSGSMEPGYYRGDTLALYHPPKIHAGDVVVYQINGRDIPIVHRILSLHTSKDNKFHLLSKGDNNNIDDRGLYDPHQYWLENEHVLGLSVGYTPYIGILTIWINEYPVVKWAIVSIMLIMILMGYE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:18054093, PubMed:30127496).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, PfSPC21, Signal peptidase 21 kDa, PfSP21.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Partially colocalizes with SPC25 in the endoplasmic reticulum.
Protein: PLSY_ANADF
Sequence: MSDTVLGLVLVAAGYLAGSIPFGVVLGRFVLGVDVRQVGSGNIGATNVARAGGKKLGIAVLLLDAAKAIVPILVARWLLAGTPRAELFTVLVALAAFVGHLYPVWLGFRGGKGVATGLGIFLVLSPWAALAGAVTYGVAYGATRISSVGSLSGTAVCVLGTFVAHGWTSPVSWAGLALAALIVVRHRENIRRLVRGEEKRMRV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPA_STRM5
Sequence: MNTADPRKRFPRSARVRTRAEYSTVFNGARRVSDPLMTLHWLPADRPARLGLAVSRKVDPHAVGRNRIKRVLRDALRQTRTDMQPGDFVVVARSAARNASNDDIRQAFLRLLRRLRALPTPGVDGTMPPPDGIATPSLTEPAPRSGTAEPAR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GUAC_PEDPA
Sequence: MKVFDYEDIQLIPAKCIVRSRTECDPTVVLGEHRFKLPVVPANMQTIINEEIAEKLAEDGYFYIMHRFEPERRMDFVKKMKDKGLISSISVGVKDDEYALIDQLAEENLTPDYITIDVAHGHAQSVIDMIHYIKEKLPAAFVIAGNVGTQEGVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLSALRWCAKVARKPLIADGGIRTHGDIAKSIRFGATMVMIGSLFAGHIESPGETKVEDGVKYKEYFGSASQYQKGEAKNVEGKKIWIHQRGHLRDTLQAMREDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDVL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: HIS1_BACAC
Sequence: MRNIQIALTKGRLEKHVIPLFEQIGIDCSELKNKGRKLVFQSKNTDISFILVKAVDVATYVEHGVADIGVVGKDILMENEKDIYEMLDLGVGVCKFCVASIPTYNPKSYRKKCIATKYPHITSNYFHNKGEDVEIIKIEGSVEIAPILGLADAIVDIVETGKTLQENGLIVFEEMYSISARMIVNKAALKTKKDEIFSIINMMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_BRUSI
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKPVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.