PharMolix/UniProtQA huggingface dataset:
Protein: DYP_AURAJ
Sequence: MRLSPVFVALLSGLLAADLGLARSVAPRVADSPAAVTGTRKTSLLKNVAGLPPVPSAAQVAATSLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA
What is the function of this protein?
Manganese-independent peroxidase that is able to convert a large number of compounds, but its physiological substrate is not known.  In addition to classic peroxidase substrates (e. g.  2,6-dimethoxyphenol), oxidizes dyes such as Reactive Blue 5 and Reactive Black 5.
What are the official names of this protein?
Dye-decolorizing peroxidase AauDyP1, AjP I, Manganese-independent peroxidase I.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: STU1_COCIM
Sequence: MDARATELLATLRNGNVSVDVKTTSLAKLKSEIKQKHVPDAAISPLFESFRLAIASQHYSLSSAGFSALGHLLKRLTLQEQHEAIALQGRATYQLLLERLGDHKERIRSQAAQAFTDFWPAASADVEHHVLGAALIGKNARAKETSMVWLAKMTREYGLLFRIYVPALVTCLEDADGVVRDTAKSTVIELFQSAPPRAISDLKKQLIQNNVRKSIATSILSSLGANIVADSETSSSFQSQSRSDITRPATSFSHRREEVPRSQSVLSMRSHSNADVHNIPKIDAAFKSQSKPTRSGHSSKDPTLSHTASSESLPAPRQDTTDGEGVEPLYINSHREFDDTIREMLPHFEGKESEQNWILREKSIMTLRRLTKGNAPHDYQQYYLAGIKSVLDGILKTANSLRTTLSAAGCYLLQDIARTCGPAIDPMVEILLQSLIKLSAALKKITAQNGNVTVDVIIGNVSYTARILQHIWGACQDKNVQPRQFATGWIKTIIIRQGKHKGSIEHSGGLDLIEKCIKKGLGDPNPGVREGMRGTFWAFYSVWPERADVIMSALEPKSKNLLERDPNNTHRGVASQSFDGSRGSQPHSTKSSLKEAINAQKKARLAASSNVPSRPESAQSSFPDPKSGRPAPRRPTGTSTIRVPTGEKLSQSASLSSAPMRPASRPRRPELVRPATADPYSSRRSAAPTAQSKASSPSDSPQKSKSKLMTTPRSRNPLARPKSRMDNAANVTNDKQRADPAATLAPKMRRRGPSEPDVVSAAARARIAILSPSRTEGDFSVASSQVKIDQKAEEAFQGTPTRGIENGTPLPASPLRSPLKGAFSTPTRNRKSSDGAPPSRIPISPSYSSRRSSEEPMLPRTPLDSRRSRGESDEAASQIPAPVDQSPIIDAINSQSPGILKVYEDPQSPHSKHSIVLGDTVPKTPGSQAKVMPLEELPLNESTTVPNRKHNQLPEHTPLLQPSPILTPSSENSHRRWKKVEGSERRRSLSPRSKDPVKAQDMITRGLARIRTGALDVHGYRKFQNLIKYHESISKDDTKYEDILMALLEALEKPDGDKGAPSGRSLDLKTQVLVTIRLMLVINREAFAAFYPRVMTAIITARKQYELTNHIVSGLEETAEDIVSACNPPQVIDAILDLLETEERSFESYRMVAMGSYILSGLLRRLNNQKLYLSQAELERLGKFANENLRSTQPDVRRAIIDFCPELYDMVQSEDAFWSMVNSSVEDFRPLLTYYIMRRPEKIG
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein STU1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: URE2_HAEIN
Sequence: MIPGEYQLAEGDILANVGRKTVKIEVTNSGDRPIQVGSHYHFFETNNALKFDRTLARGMRLNVPSGNAVRFEPGEVKSVELVAFGGNQIIYGFHNQIDGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_STRP3
Sequence: MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTTHVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2253_BACCR
Sequence: MKKTFYHYMMKHRAALFRNEISDLAEAMYDDLSFPKQSEDYDEISSYLELSGMLESMSIFDEAWDLYIQDR
What are the official names of this protein?
UPF0346 protein BC_2253.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: GLYDT_BPPAM
Sequence: MSRNYEKLSIEEFGAHLLGTVDLDPIYLALRRMELPEAQLNRWLLAYWCLYNGGEASYLSEFEGREFFEMLNHAAENVREAPIGGRWPRGAERRHWRGAQATSSVEYLIDRYDDRPEDMAAYCAGQGGTFLEVTKRVQEHRLFGPWIGFKVADMVDRVLGKPVSFDNAAVFMFKDPYKAACIQYEVNPNIPDHVLADGSVAPRNRELVTPETVHHVAQHLIEHFKGFQAPPLGDRPVNIQEVETILCKWKSHQNGHYPLFKDIVEIREAALPWAKVSKTAQAFFEAMPEVTQ
What is the function of this protein?
Transfers glycine to 5-phosphomethyl-2'-deoxyuridine (5-PmdU) to produce 5-Nalpha-glycinylthymidine (Nalpha-GlyT) on DNA as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-acetylaminomethyl-2'-deoxyuridine (5-AcNmdU) substitutes for a subset of thymidines in the viral DNA (PubMed:34522950).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
Glycinyltransferase, Amino acid:DNA transferase, AADT, gp46.
What is the protein family that this protein belongs to?
Belongs to the thymidine aminotransferase family.
Protein: MAO1_ECO7I
Sequence: MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWHAEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: KTHY_STAAR
Sequence: MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQGYARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQNRLDQEDLKFHEKVIEGYQEIIHNESQRFKSVNADQPLENVVEDTYQTIIKYLEKI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FABR_SHIBS
Sequence: MGIRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_ECODH
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: TPIS_ALIF1
Sequence: MRHPVVMGNWKLNGSKEMVVELLNGLNAELEGVTGVDVAVAPPALFVDLAERTLTEAGSAIILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHNESDEFVAKKFAFLKENGLTPVLCIGESEAQNEAGETVAVCARQIDAVINTQGVDALNGAIIAYEPIWAIGTGKAATAEDAQRIHAQIRAHIAEKSEEVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAALDAKSFAAIAKAAAEAKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_CANLF
Sequence: MVKQIEFKYAFQEALNSAGDK
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).  Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.  Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.  Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA). Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. Secreted by a leaderless secretory pathway.
Protein: ICEN_XANCT
Sequence: MIVEKILALRTCANNMADHCGLIWPMAGPVECKFWKPSGLHENGLTGLLWGKGVGAHLSAHADARWVVCEVAVDEMLQLAEEGMIKFPRATVLFVGNRSQALDYIAANMPLYGAALQLAAPAAPAHVHMPAAEPSAPATQATSATLPTPATPSTQATPSTQSTQSTQSTEATQSTEATPVATVAAAPPPPGQQHDVMAKKTETGVYGSTLTGADQSRLVAGYGSTETAGDHSDLIAGYGSTGTAGSDSSILAGYGSTQTAAGRSTLTAGYGSTQTAQEGSRLTSGYGSTATSGSDSAVISGYGSTQTAGSESSLTAGYGSTQTARKGSDITAGYGSTGTAGSDSALIAGYGSTQTAGSESSLTAGYGSTQTARKGSDVTAGYGSTGTAGADSTLIAGYGSTQTAGGESSLTAGYGSTQTARQGSDITAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDITAGYGSTGTAGSDSSLIAGYGSTQTAGSESSLTAGYGSTQTAQQDSSLTTGYGSTSTAGHDSSLIAGYGSTQTAGYDSTLTAGYGSTQTAQQDSSLTTGYGSTSTAGADSTLIAGYGSTQTAGSDSSLTAGYGSTQTAREGSDVTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDVTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDVTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDVTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDITAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTAREGSDVTAGYGSTGTAGADSTLISGYGSTQTAGSDSSLTAGYGSTQTARKGSDVTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTARKGSDMTAGYGSTGTAGADSTLIAGYGSTQTSGSDSSLTAGYGSTQTAREGSDVTAGYGSTGTAGADSTLIAGYGSTQTAGSDSSLTAGYGSTQTARQGSDVTAGYGSTGTAGADSTLIAGYGSTQTAGSDSSLTAGYGSTQTARQGSDITAGYGSTGTAGADSSLIAGYGSTQTAGYDSNLTAGYGSTQTAREDSSLTAGYGSTSTAGHDSSLIAGYGSTQTAGYNSILTTGYGSTQTAQESSSLTAGYGSTSTAGYDSTLTAGYGSTQTAGYKSTLTAGYGSNSTAGHESSLIAGYGSTQIAGYESTLTAGYGSSLTTQQNSSLTAGYGSTEIAGYASTLMAGYGSSQTAGYESTLTAGYGSTQMAEHSSSLTAGYGSTGIAGQDSSLIAGYGSSLTSGVRSFLTAGYGSNMIASYGSSLIAGHECTQIAGHKSMLIAGKGSFQTAGARSTLIGGAASVQTAGDRSKLIAGADSTQTAGDRSKLLAGRNSYLTAGDRSKLTAGDDSTLMAGDRSKLTAGKNSVLTAGANSRLIGSLGSTLSGGENSTLIFRCWDGERYTNLVVRTGEQGVESDIPYQVDDEGNLVGKADDDLVLDYDPGMILDGQCSPGTGEELRDV
What is the function of this protein?
Ice nucleation proteins enable bacteria to nucleate crystallization in supercooled water.
What are the official names of this protein?
Ice nucleation protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial ice nucleation protein family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: RAB2A_MOUSE
Sequence: MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHGSNQGGQQAGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology.  Required for protein transport from the endoplasmic reticulum to the Golgi complex.  Regulates the compacted morphology of the Golgi.
What are the official names of this protein?
Ras-related protein Rab-2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid.
Protein: ASTC_ECOSE
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: ZN148_PONAB
Sequence: MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESALDKSDLKKDKNDYLPLYSSSTKVKDGYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLTTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSTDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDSRAGMTSSPDATTGQTFG
What is the function of this protein?
Involved in transcriptional regulation.  Represses the transcription of a number of genes including gastrin, stromelysin and enolase.  Binds to the G-rich box in the enhancer region of these genes (By similarity).
What are the official names of this protein?
Zinc finger protein 148.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_FRATM
Sequence: MQIKRWFLNNSLRNYQYLLYDKSHAIVIDPLKSDIFAEFIAKNKLQLEAILITHKHGDHIAGVKKLLAIYLNAKVYAYTGNDLFKPDIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFEQERALFCGDTLFNAGVGGVQAESADINQLYDSLVKITKLDGDIKPYPAHDYWLGNLDFALSILADDSYFNYYRNQVAELAAEDKPIVNLAEEAKLNIFIRAMSDKALLKALPDYSLGREMFVKLRQLKNNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: FGL2_BOVIN
Sequence: MKLANWCWLSSTVLATYGFLVVANNETEEIKDEAAQNACRVRLESRGRCEEEGECPYQVNLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKTCQDCKLQADDSRDPGRNGLLLPGTGAPGETGDNRVRELEGEVNKLSSDLKNAKEEIDVLQGRLEKLNLVNMNNIEQYVDSKVANLTFVVNSLDGKCSSKCPRQEQIQSLPVQQHLIYKDCSEYYTIGKRSSELYRVTPEPRNSSFEVFCDMETMAGGWTVLQARVDGSTNFTRTWQDYKVGFGNLRREFWLGNDKIHLLTKSKDMILRIDLEDFNGIKLYALYDHFYVANEFLKYRLHIGNYNGTAGDALRFSKHYNHDLKFFTTPDRDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGISEAQPGGYKSSFKEVKMMIRPKHFKP
What is the function of this protein?
May play a role in physiologic lymphocyte functions at mucosal sites.
What are the official names of this protein?
Fibroleukin, Fibrinogen-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_STAAC
Sequence: MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: URE3_STRTR
Sequence: MQLTMREQEKMMISLAAMIAQRRKDKGIKLNHPEAVALITDYVLEGAREGKTVAQLMDEARNLLTREDVMEGIAEMIPMIQVEATFTDSTKLVTVHDPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_THEAN
Sequence: MAKPEPDVVVPEGDPAKGAKLFKSKCAQCHTINKGGSVKQGPNLFGFYGRKSGSTDYAYSDANKNSGIVWSDKHLFVYLVNPKQYIPGTKMVFAGLKKEQDRADLIAYLKEASSK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: NB5R3_HUMAN
Sequence: MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF
What is the function of this protein?
Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor.
What are the official names of this protein?
NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid- anchor; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Produces the soluble form found in erythrocytes.
Protein: RIP5_SAPOF
Sequence: VTSITLDLVNPTAGQYSSFVDKIRNNVKDPNLKYGGTDIAVIGPPSKEKFLRINFQSSRGTVSLGLKRDNLYVVAYLAMDNTNVNRAYYFRSEITSAELTALFPEATTANQKALEYTEDYQSIEKNAQITQGDKSRKELGLGIDLLLTSMEAVNKKARVVKNEARFLLIAIQMTAEVARFRYIQNLVTKNFPNKFDSDNKVIQFEVSWRKISTAIYGDAKNGVFNKDYDFGFGKVRQVKDLQMGLLMYLGKPK
What is the function of this protein?
Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.
What are the official names of this protein?
Ribosome-inactivating protein saporin-5, SAP-5, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: ATP25_FUSV7
Sequence: MITRPVAAALSCRQCRSAILRAVVSRPTASSLRTLPQRQARQLPILTRRFFSEEKTIEPKGERVAEVLVTPDNAPETKDTAESDDVPWFLEVEPPRHPESQHKVELPKIPEDAPEVIGPMIKYIFEDMGLDDISLLDLRDLDPPAALGPNLIMLFGTARSERHLHISSGRFVRWLRKNHSIAARADGLIGPGELRTKLRRLRKKAKLLGTNTAIIPGGDNGISTGWVCVHFSSSGDNINEAASFDDSGRFSGFGAPQTGTTVVVQCMTEARRGELDLETLWQAILKKNLQENKKARGEKFADAEELNKVLASKIQLPSSASALQWQAMQKASQQHRSYSTSARRLSPSLEREQPASNLLNEEPEFAEEPVVLDLALVQKHIQDIQLIGTPMTQEMLYNLIKGAMMTPSPNNAAKDRLSLVDQILLTAEERGMEIWNDEMFVTLIEAGLLSPCYGLEIQRAQKNLEYLMKQKGCQFNGDQVLRLMNAYAYQKDWDRFWDAFRMPPRFKMARESQHYELAYRAMALTSSQKMCIAALRWVYPEMMSQDPPILLVSPLYDSLKACLTVADPGALTWMHNASETKLINLRPVQRRRLENREFLKVMREVESIRAELMRAGLVQSESGALHQ
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HTPX_SHEB8
Sequence: MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLVETVARQAKQAGIKMPEVAIYQSSDMNAFATGPSKDNSLVAVSTGLLYGMSQDEIEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYKADEGAARLAGKGKMIAALERLRQGPESTAMPAQMSAFGINGKRSMAEMMMSHPPLEKRIAALRAS
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCOR_TRYBB
Sequence: MDIVVNDDLSCRFLEGFNTRDALCKKISMNTCDEGDPFFVADLGDIVRKHETWKKCLPRVTPFYAVKCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHIRYARDSGVDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSLARCRLSVKFGAKVEDCRFILEQAKKLNIDVTGVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFNMHILDIGGGFPGTRDAPLKFEEIAGVINNALEKHFPPDLKLTIVAEPGRYYVASAFTLAVNVIAKKVTPGVQTDVGAHAESNAQSFMYYVNDGVYGSFNCILYDHAVVRPLPQREPIPNEKLYPSSVWGPTCDGLDQIVERYYLPEMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTIYYVVSGLPDHVVRELKSQKS
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.