PharMolix/UniProtQA huggingface dataset:
Protein: EME1A_ARATH
Sequence: MSDFILISDGEDEATPPPSKRARKNRTPTDLNLDTEPSLQKQPPGSASTPFFLDETPLSDDVTVLKSSFGSGTGASSGRENNFFGKRVISLESDSEDSPGPESSKKYEPVYTDSWKKPCRLEFGSSDANSDDDPSWMRRASFQSSLSKDAIEVDSDHEKEDTGVEKMGRKKQTITSKSTSLSADSLPKKKMSKDEKTRAAEEKKLQKEQEKLQKAASKAEDAEHKKLEREKQKWAKEKDKALKCIVAWIDNKVLEGSFGGLLISGLKEKCITYHVTTNPIQRSIVWTMTLPEDIAQSLPLGSKIPYVLLLYEAEDFCNLVAKKELLENVYRVRDEYPSYTMCYLTNKLLSYVNKKERVEYKDPVNGCGWRKPPIDEAIAKLSTHYIGVHSRHCVDEAEVADHVVRLTSSLAHCQVRKKLTRLSVYADGTLMSKNAADKHLIRESIWLKVLVAIPKVQPRYAIAVSKKYPSLKSLLKVYMDPNISVHEKEFLLKDLKVENLVGRDTSVGEACSKRIYRVLMSLDGTIKTDDVENGAASFTLPPSDLI
What is the function of this protein?
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells.  Mediates a subset of meiotic recombination events that are insensitive to crossover interference.
What are the official names of this protein?
Crossover junction endonuclease EME1A, Essential meiotic endonuclease 1A, AtEME1A.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MP2K3_MOUSE
Sequence: MESPAASPPASLPQTKGKSKRKKDLRISCVSKPPVSNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVDFTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
What is the function of this protein?
Dual specificity kinase.  Is activated by cytokines and environmental stress in vivo.  Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.  Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK/ERK kinase 3, MEK 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: ZN865_MOUSE
Sequence: MEANQAGSGAGGGGSSGIGGEDGVHFQSYPFDFLEFLNHQRFEPMELYGEHAKAVAALPCTPGPPPQPPPQPPPPQYDYPPQSSFKPKAEAPSSSSSSSSSSSSSSSSSSSSSQAKKMDPPLPPTFGAPPPPLFDAAFPAPQWGIVDLSGHQHLFGNLKRGGPTPGPGVASGLGTPTGTPGPLTTPSQTPPGPAVGAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGICGRTYNHVSSLIRHRRCHKDVPPTPTGGTPQPGPALPSLGLPVSTASATASSDPAAVSSGPSATPATPATSTDGNTTPAAPPGVAMPPSATTGGDGPFACSLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICGKVFRDASYLLKHQAAHAAAGTPRPVYPCDLCGKTYSAPQSLLRHKAAHAPPVATEPAKDGAASVPQPPPPFPPGPYLLPADPSTTDEKATAAAAAVVYGAVPVPLLSAHPLLLGGAGNGGAGGPGAGGPSKTFCCGICGRAFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGATGLATGQGTTGACGPGAAGTSGGPADLSYACSDCGEHFPDLFHVMSHKEAHMSEKPYGCDACGKTFGFIENLMWHKLVHQAAPERLLAPTPSGPQSSDGGSSGGGTDASSVLDNGLAGEVGTAVAALAGVSGGSEDAGGATVAGSGGGTSSGAERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKHFAQSSSLAEHRRLHAVARPQRCGACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLMHKAEGLGMPGTGGSALAGKDP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 865.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAC_ECO5E
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIISDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: RUVB_LEVBA
Sequence: MVDDERVVSPETADDHEDSVEKSLRPQVLAQYIGQEPIKHELSVYIQAAKQREESLDHVLLYGPPGLGKTTLAMVIANEMGVQIRTTSGPAIEKPGDLVALLNELQPGDILFIDEIHRLPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTLIGATTRAGLLSAPLRDRFGIVEHMAYYETTDLQEIVLRSADIFHTAIATEGAHEIALRSRGTPRIANRLLKRIRDFAEVAPDHDQIDLAIVDHALDLLRVDSAGLDATDIKLLETMIDYYNGGPVGLNTLAANIGEETETVAAMYEPYLLQRGYLKRTARGRVVTATGYQHLGRTMPDNN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATPG_SALTO
Sequence: MAAQVRVLRQRIRAAKSMKKITKAMELVATSRIAKAQEQVAASLPYSRAITEVLTALASNTRIDHPLLTPRERVRRAGVLLVTSDRGLAGGYSSNAIKTAESLLARLRADGKEPSLYVIGRKGVQYYRFRNRPMMACWTGFSEQPTFADAREVGETLIKAFTAGVDDGDGDPGPDGVFGVDELHIVSTEFKSLMTQVPVPKILGPMQIEDRPRSEGILPAYEFEPEAEALLDALLPKYINTRIYAALVESAASESASRRRAMKSATDNAEEMIEKYTREMNSARQAGITQEISEIVGGANALAASGSEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SURE_SALAR
Sequence: MRILLSNDDGIHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQIKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP2_AMOCU
Sequence: MFTLKKPLLVLFFLATINLSLCEQERNAEEERRDDDERNVEVEKRFFPIVGKLLSGLFGK
What is the function of this protein?
Antimicrobial peptide active against a variety of Gram-positive bacterial strains but not against Gram-negative bacteria.  Has weak antifungal activity against a slime mold isolate.  Has weak hemolytic activity against human erythrocytes.
What are the official names of this protein?
Temporin-CG2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPRTL_STRS2
Sequence: MDLNKYVQEVSLQDFGKEFRHVAIWNRRLRSTGGRFFPRDGHLDFNPKHLEEQGLEVFRKIVRHELCHYHLYFEKKGYRHGDRDFKELLAAVDGLRYAPQLEQATKPSLIYCCQSCGQVYQRKRRIDLKKYRCGKCRGKLTLKE
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_ACET2
Sequence: MRLRKKPWARPALEACSFFVINPTEYKGKWREVFGNSNEIWLELGCGKGGFISKLASTNPDKNFIAVDIKDEVLALAMKKIENEYALIGAETKNIRLMAHEIMLIHRMLDENDQIGRIFINFCNPWPKNRHKARRLTHPNQLNQYRTFLAPNGQIWFKTDDTMLFQDSIKYFEQCNFNIVYLTEDLHASGFEGNIETEHERMFLEQGCKIKFLIAEKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ZC3HF_DROPS
Sequence: MPPKKAPAGPSKKTEQKKKEKVIEDKTFGLKNKKGNKQQKFIQQVQKQVQAGGHHPRQDGDKKKDEKEKKLADLREMASIFKPVQTQKVDKGTDPKSVVCAFFKQGLCTKGDKCKFSHDLSLENKVEKRSMYVDMRDNEDDLMTNWDDAKLKEVVDKKHSEEKRRPTTEIICKFFLEAVEKSKYGWFWECPNGEKCIYRHALPPGYVLKRDKKKEDKPTEISLVDLIEKERAALGSNQTRVTLETFLAWKKRKLQEKKAKMVAEEERKKSDFSKGKQFGISGREMFSFNPDLVDDGPIEEGDAAFDVYKREDDDDDNAFEFKELDLAALSLAAKEVDGSGTIASSTRLLDQATEAAKTAAAEDGAASDDENPSSSAPANDAAPFNKDLFVDLAGELDDLDLDDEDD
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 15 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZC3H15/TMA46 family.
Protein: RS24_PICTO
Sequence: MAKLEFNVDMERDNKLLFRKEINYTIKFENDKTPSREDIRKLLANNYGSDESLIIVDKNRQETGKHEIKGYAKIYDTKEHAMLYEPDYELFRNKLKVKEGNQ
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: SDIS_COMTE
Sequence: MNTPEHMTAVVQRYVAALNAGDLDGIVALFADDATVEDPVGSEPRSGTAAIREFYANSLKLPLAVELTQEVRAVANEAAFAFTVSFEYQGRKTVVAPIDHFRFNGAGKVVSMRALFGEKNIHAGA
What are the official names of this protein?
Steroid Delta-isomerase, Delta(5)-3-ketosteroid isomerase.
Protein: Y1316_HAEIN
Sequence: MPEPYYSMYRKEDVVLDKSFFTPLEGKPDHFRTISKMWGMWEASEDHWKEVITKFWGYITLIEDDNLVYLHDLTSTVFDLANQKVPESFEGQSVLPIMRQHQDNQRKGVLGQLAGHFVYFEQRMWRRKDYKLVFNATDVCELYNIRNDPEEMHNLFYDPQYNRIKKEMLEEMRAEMKRLNDPLENWVYRIIDEI
What are the official names of this protein?
Uncharacterized protein HI_1316.
Protein: DAM1_YEAST
Sequence: MSEDKAKLGTTRSATEYRLSIGSAPTSRRSSMGESSSLMKFADQEGLTSSVGEYNENTIQQLLLPKIRELSDSIITLDSNFTRLNFIHESLADLNESLGSLLYGIMSNSWCVEFSQAPHDIQDDLIAIKQLKSLEDEKNNLVMELSNMERGIKRKKDEQGENDLAKASQNKQFNQPLFPSSQVRKYRSYDNRDKRKPSKIGNNLQVENEEDYEDDTSSEASFVLNPTNIGMSKSSQGHVTKTTRLNNNTNSKLRRKSILHTIRNSIASGADLPIENDNVVNLGDLHPNNRISLGSGAARVVNGPVTKNRNSMFSGRAERKPTESRHSVAKKTEKKINTRPPFR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B.  Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
What are the official names of this protein?
DASH complex subunit DAM1, DUO1 and MPS1-interacting protein 1, Kinetochore assembly protein DAM1, Outer kinetochore protein DAM1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: DNLJ_SACD2
Sequence: MAASDAVLDKLESLKNQINYHNKLYYVLDAPELPDAEYDKLFQELQAIEQQFPELVTEDSPTQRVGAAPLDSFASIEHKRPMLSLDNVFNVEELFAFDKRIRDRINADASLEYSCEPKFDGIAASLLYENGRLKTAATRGDGTVGEDITQNMRTIGSVPLKLEGNNIPAVLEVRGEVYMPKAGFLRINEEALAKNEKTFVNPRNAAAGSLRQLNPQITAKRPLVFCAYNVGVVEGGELPATHYETLTQLFEWGFLVSEERRIAKGIEECEAYYHYLEAKRESLAYDIDGIVFKVNAFDLQERLGFVSRAPRWAIAHKFPAQEALTVLHDVEFQVGRTGAITPVAKLQPIFVGGVTVSNATLHNKDEIERLGIRVGDTVIVRRAGDVIPQIVSIVESKRPQDAREIKFPTACPVCGSDVESVEGEAAIRCTGGLVCEAQRKESIKHFASRQAMDIDGLGDKIVDQLVDNKLVNDVADLYTLDIPTLAGLERLGAKSAANLVAAIEASKQTSLDKILYALGIREVGRATARNLANHFCTLNKVMDATQEQLIEVTDVGPVVAHYVVDFFAQANNREVIEKLIAAGVNWPDIEKVDGVKPLEGTTYVLTGSLESLSRDEAKDKLQALGAKVSGSVSAKTTCVVAGPGAGSKLAKAEKLGLAILDEVGLLALLEEHGV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MCS1A_XENLA
Sequence: MFKKFDEKENVSNCIQLKTSVIKGIKNQLIDQFPGIEQWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAADTVVAIMAEGKQHALCVGVMKMSADDIEKINKGIGIENIHYLNDGLWHMKTYK
What is the function of this protein?
Plays a role as translation enhancer and involved in cell cycle regulation.
What are the official names of this protein?
Malignant T-cell-amplified sequence 1-A, MCT-1A.
What is the protein family that this protein belongs to?
Belongs to the MCTS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_POLNS
Sequence: MALLQISEPGKSLAPHQRRIAVGIDLGTTNSLVAIVRDALPKVLPDAQGRELLPSVIRYLPNGRTQAGFEALESVVIDPKNTIVSVKRFMGRGLLDVEHIESAPYDFVDQPGMLKLRTVAGDKSPIEVSAEILARLRQLAEDSVSDEIVGAVITVPAYFDDAQRQATKDAAKLAGIEVLRLLNEPTAAAITYGLDNASEGVYAVYDLGGGTFDISILRMSRGVFEVLATGGDSALGGDDFDHRLYCWVIEQAKLPPLSIHDHRTLLQACKHAKEQLSHNPLARVHETLADGTVVNVGISQAQFFEITQNLVTKTLMTCKKALRDAGLKAEDVKGVVMVGGSTRMPNVQRAVAELFGTQPLNNLNPDQVVALGAAMQADLLAGNQSKDDEWLLLDVIPLSLGIETMGGLVEKSIPRNTPIPVARAQDFTTFKDGQTALAIQVVQGERELAQDCRSLGRFELRGIPAMAAGAARIRVTFQVDADGFLSVSATEQGSGVKASIDIKPSYGLTDAEITRMLQDGFASAKEDLLSRSLREEQVNAQRLLDAVQTALDSDRSLLNAEEQAAIDREMTTLQKILNEETNSAVVRKAVDQAVKATDDFAQKRMNASIQKALSGKNVTEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TIM21_YEAST
Sequence: MSSSLPRSLLRLGHRKPLFPRYNTFVNSSVITHTSLLRTRLYSNGTGATSGKKDDKTRNKPKPLWPQVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLQCDDGITGKERLKAYGELITNDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPKLHPVSNSKGFLGIRWGPRKD
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to keep the TOM and the TIM23 complexes in close contact.  At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix.  In the complex, it acts as an antagonist of TIM50 by reducing preprotein accumulation at the TOM23 complex and promotes dissociation of the PAM complex from the TIM23 complex.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM21.
What is the protein family that this protein belongs to?
Belongs to the TIM21 family.
Protein: MHUD_MYCTU
Sequence: MPVVKINAIEVPAGAGPELEKRFAHRAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLDVGGTGKTA
What is the function of this protein?
Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (mycobilin-producing), Mycobacterial heme utilization, degrader, MHUD.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family.
Protein: MYC1_XENLA
Sequence: MPLNANFPSKNYDYDYDLQPCFFFLEEENFYHQQSRLQPPAPSEDIWKKFELLPTPPLSPSRRSSQSSLFPSTADQLEMVTEFLGGDMVNQSFICEADDEALLKSIVIQDCMWSGFSAAAKLEKVVSEKLASYQASRKESALSSSSPCQSQPPPSPLKSPSCHGSLSLGGTHRSSHGFLQDPSSDCVDPSVVFPYPLNDSISNASSPCQDLILETPPISSNSSSSESEEEPEDEDEDCDEEEEIDVVTVEKRQSASKRVESSSHSQPSRPHYSPLVLKRCHVPIHQHNYAASPSTKVDYVSSKRAKLESNIRVLKQISNNRKCASPRSSDSEENDKRKTHNVLERQRRNELKLSFFALRDQVPEVASNEKAPKVVILKKATEYAISLQEDERRLIRETEQLKYRKEQLKQRLQQLRNFV
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.
What are the official names of this protein?
Transcriptional regulator Myc-A, c-Myc I.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHAF1_DROME
Sequence: MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGVRLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPGVYDAAKQLFALHFRGLSFYFPVDSKLHSGYAHGLSSLVFLNGASPVVSKMSLYAGSNVLENRVPSLPLSCYHRQMYLESATVLRTAFGHTKGLKLKLFTEGSGRALEPRRQCFTRELLFGDSCEDVATSLGAPNRIFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFTLGIDVLFDARTQTCKKFILHTNYPGHFNFNMYHRCEFQFLLQADHPSMSDSGHDLVTPTKQEHVNITAYTKWDAISSALATSERPVVLHRASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNTAPPRQPAHSWQQHKMQDIRLTVA
What is the function of this protein?
May play a regulatory role in autophagic activity.
What are the official names of this protein?
PHAF1 protein CG7083.
What is the protein family that this protein belongs to?
Belongs to the PHAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner.
Protein: RECF_MOOTA
Sequence: MPALSLQQLQLINFRSYKCLTWDCRPGLNIIFGPNAAGKTNLLEAIGYLALARSFRQQQDQQLLTWGASSFQVRGLCHSNGEKIELVINYQQHNKRLTINGNRNRLIELLGIFPVIYFGPDDLHLLKGGPAYRRHFLDREISMGDRLYCRNLQDYRRILFQRNLLLRAIKAGRGKEGELEPWDIQLLATGKAICEKRSCFLQSLAPRVAATYRDMAGGEELALIYRPGVASQEEWAERLKVGREREVQAGMTLWGPHRDDFTFTLDGHEARYFASQGQQRAIVLALKLAEARYYRELLHVMPVLLLDDVFSELDEAHQGALLELLAGADQAFLTTTEVGLLPARLIQRSHLWELARGREPRLTSGPVEAQ
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y189_SYNY3
Sequence: MTDLGQAGESLVAAWLEQQGGKILQQRWRSPWGEIDLITHFPDTKIIAFVEVKTRSGGNWDQGGLLAVNARKQEKIWQTANHFLASQPQWSDWNCRFDVMIVFSQGSVPTGENAEGKFANLPTNFQMGQTIVWQGYRLRLEQYLTDAFGG
What are the official names of this protein?
UPF0102 protein sll0189.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: YDR22_YEAST
Sequence: MLESSSDKIKFAPIKEVDYKKPVSKSKNYTLINDIQPLEWYCHNDSETGYQHTISNKTDGGRGLFRVMKKSMETRVETQTLYFTDLHTGLCGFVQLLYSTVMGGIYKGFQLNFKVFGSESNNTDYDVWESFKLDDIAEFQPLKFVSRNVIFEFLSNKNEKLGSIGQLSIKCDLPTCNNTIQNLKIDLLVDLFQGFKMNPNGCNYYFDKQISMSDEFVSSDKMIRHVFVPRGKCNGNISYDKKLNSGDFQNKNISLTDVPVVYLDAVQGLLPNKAASKWNFLCFQSENYSVLAIEFTTPRDHDNVTVTVWSITEKNKLISIGSSVQSPKRHVRFRATSTDKESGWVYPTSIKFPGGFSEHDLRLVNRYDVLGELPSMVRSLAQKIVSIKPFIYQYCQPSKYKHEKGISIVESTFIS
What are the official names of this protein?
SVF1-like protein YDR222W.
What is the protein family that this protein belongs to?
Belongs to the SVF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Punctate pattern.
Protein: LSPA_STAA2
Sequence: MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAGALGNFIDRILTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y047_LACP7
Sequence: MAKRGGFPGGNMPGNMNNLMKQAQRMQKQMEDKTKEMEEKQWEATAGGGAVTVTVSGKKEVVSVKLSKEVVDPDDIEMLEDLIVAATNEALRKMEEESASAMNSIAGGLGNFGGLGGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Cphy_0047.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ERF36_ARATH
Sequence: MTSLNSSASPTSSSSDQSDATTTTSTHLSEEEAPPRNNNTRKRRRDSSSASSSSSMQHPVYRGVRMRSWGKWVSEIRQPRKKTRIWLGTFVTADMAARAHDVAALTIKGSSAVLNFPELASLFPRPASSSPHDIQTAAAEAAAMVVEEKLLEKDEAPEAPPSSESSYVAAESEDEERLEKIVELPNIEEGSYDESVTSRADLAYSEPFDCWVYPPVMDFYEEISEFNFVELWSFNH
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF036.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.