PharMolix/UniProtQA huggingface dataset:
Protein: NEK7_HUMAN
Sequence: MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS
What is the function of this protein?
Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:31409757, PubMed:19941817).  Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis (PubMed:17586473, PubMed:19414596, PubMed:31409757, PubMed:19941817, PubMed:26522158).  Phosphorylates EML4 at 'Ser-146', promoting its dissociation from microtubules during mitosis which is required for efficient chromosome congression (PubMed:31409757).  Phosphorylates RPS6KB1 (By similarity).  Acts as an essential activator of the NLRP3 inflammasome assembly independently of its kinase activity (PubMed:26642356, PubMed:36442502).  Acts by unlocking NLRP3 following NLRP3 tranlocation into the microtubule organizing center (MTOC), relieving NLRP3 autoinhibition and promoting formation of the NLRP3:PYCARD complex, and activation of CASP1 (PubMed:26642356, PubMed:31189953, PubMed:36442502).  Serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division: interaction with NEK9 prevents interaction with NLRP3 and activation of the inflammasome during mitosis (PubMed:26642356, PubMed:31189953).
What are the official names of this protein?
Serine/threonine-protein kinase Nek7, Never in mitosis A-related kinase 7, NimA-related protein kinase 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Present at centrosome throughout the cell cycle (PubMed:17586473). Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody (PubMed:17586473). Interaction with ANKS3 prevents its translocation to the nucleus (By similarity).
Protein: UFSP2_DANRE
Sequence: MGFQSSVEGLTQASACGDILQYIESDDGGNKKSSKKKDKKKSGPIVVNLKLLFEVTDPAGNEAPSLMRMSAQQHSVKMPLPLDCVLSVSADESMTTVFTGLVEALNKQIADMEEVVLRYRKGSSFLVPQPFHFQLPKPAGLTTVIYPAGVPDSQLQAVREDLHRKFELSLDRPYLRRANAFHFPYEAYKDGYLRNPHIHLNPPNIEDAKLYLVQGVYSYHHYMQDRVDDDGWGCAYRSLQTICSWFQQQGYVETAVPTHTQIQQALVDVGDKEPRFVGSRQWIGSIEVQAVLNQLLGVTSKIMFVSQGSELATKGRELANHFHTEGTPVMIGGGVLAHTILGVAWSENTGEIRFLILDPHYTGGEDLQIITDKGWCGWKGPEFWDQNAYYNLCLPQRPKTV
What is the function of this protein?
Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins.  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
What are the official names of this protein?
Ufm1-specific protease 2, UfSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus.
Protein: MTR1L_SHEEP
Sequence: MGRTLAVPTPYGCIGCKLPQPDYPPALIVFMFCAMVITIVVDLIGNSMVILAVSKNKKLRNSGNVFVVSLSVADMLVAIYPYPLMLHAMAIGGWDLSKLQCQMVGFITGLSVVGSIFNIMAIAINRYCYICHSLQYERIFSVRNTCIYLAVTWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYVNNPAFAVTIVCIHFVLPLLIVGFCYVKIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINALTVLVAVNPKEMAGKIPNWVYLAAYFIAYFNSCLNAVIYGVLNENFRREYWTIFHAMRHPVLFLSGLLTDVREMQEAQAHTHARARARTQAHEQDHAHACPAVEEIPMSVRNVPLPGHGAAGQPECVSGHPKPASGHSRSVSARRKSASAHPKSASGQSKSATVYPKPTSVHFKPSSVYFKADSVYFKPSSSHPKPITGPSKTAISPATSFPKPTTGYTQHATIHSEPTTLDYLEPITTSHSKPVIASHSELAASCHLECNIFDLSDPTSSPASDSSNSAASLLDPTAAAAATVNPTVVTTDYHEIVLIDVDADSDEMAV
What is the function of this protein?
Does not bind melatonin.
What are the official names of this protein?
Melatonin-related receptor, G protein-coupled receptor 50, H9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHO_MICLU
Sequence: MTESTEQTTPTNGGGLASLKLAQLQALASQLGIAGGSRMRKADLVTAISDHQRGGSVADRDAAERAAQAPAAPAAETAPAAASSEDAAPAAERPARRRSRRADADTSAPAAAQDGQPQAEAREAQTEQAPRETASDQDRSGGSEARDEGEDRPQSERRSRGRRRAGDDDAQQGQDRRSDGAQGEDGADADRRGDREDRDDNGRENGRGRNGRNGRDRDNGRDRENGRENSRDRENGRDGSREQRGDKSEDGGRGDGGRGDRSRRDDRDDEGGRNRRNRRNRNERGRNRRGRGGPEVDETELTEDDVLQPVAGILDVLDNYAFVRTSGYLPGPNDVYVSLAMVKKYGLRKGDAVVGPIAPRDGEKQQHHGGGSNRQKFNALVKISSVNGQPAVEHPQRVEFGKLVPLYPQERLRLETDPKLIGPRVIDLVSPIGKGQRGLIVSPPKAGKTMILQSIANAIKTNNPEVHLMMVLVDERPEEVTDMQRSVDGEVIASTFDRPADDHTTLAELAIERAKRLVEMGRDVVVLLDSMTRLGRAYNLAAPASGRILSGGVDSSALYPPKKFFGAARNIENGGSLTILATALVETGSRMDEVIFEEFKGTGNMELRLSRHLAERRIFPAVDVNASGTRREEALLSQEEVKIMWKLRRVLSGLEQQQALDLLTNKIKDTASNAEFLMLVSKTTLGSKGDD
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: URE2_BACVZ
Sequence: MKPGAIQVAKGIITINEGRKTLEVSVTNNGTRSVQVGSHFHFAEANGALSFNRDKAIGMRLDIPSGTSVRFEPGEEKTVTLVEIGGRKTVRGLNGMADTYMDERGKEKTLSNLKKAGWMEEAIR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_CLONN
Sequence: MKKKGIFGGTFDPIHNGHLHIAYEALYKLNLDRVIFIPSGNPPHKTDKVITDANIRYKLVKDVIQNEEKFEVSDYELKNQGLSYTYKTLKHFNEKHKDTEWYFITGADCLMQLDSWKNINEVLSLCNFVVFRRSGYSMEDMLKQKERIEKKFNKKIIFLDIPVIDISSTTIRNKIKNRENISYLVPEKARCMVNKMNLYK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PSBI_SYNE7
Sequence: MLALKVTVYVVVLFFVALFVFGFLSSDPARTPSRKDLED
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS12_POLAQ
Sequence: MPTINQLIRKPRSRLIVKSKSPALENSPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQSRSKYGAKRAKKAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GPMI_HELPY
Sequence: MAQKTLLIITDGIGYRKDSDHNAFFHAKKPTYDLMFKTLPYSLIDTHGLSVGLPKGQMGNSEVGHMCIGAGRVLYQDLVKISLSLQNDELKNNPAFLNTIQKSPVVHLMGLMSDGGVHSHIEHFIALALECEKSHKKVCLHLITDGRDVAPKSALTYLKQMQNICNESIQIATISGRFYAMDRDKRFERIELAYHSLMGLNHTPLSPSEYIQSQYDKNITDEFIMPACFKNYCGMQDDESFIFINFRNDRAREIVSALGQKQFSGFKRQVFKKLHIATMTPYDNTFPYPVLFPKESVQNTLAEVVSQHNLTQSHIAETEKYAHVTFFINGGVETPFKNENRVLIQSPKVTTYDLKPEMSAKEVTLAVLEQMKLGTDLIIVNFANGDMVGHTGNFEASVKAVEAVDACLGEILSLAKKLDYAMLLTSDHGNCERMKDENQNPLTNHTAGSVYCFVLGDGVKSIKNGALNNIASSVLKLMGLKAPATMDEPLF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: COX2_APOSM
Sequence: MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISTLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSTSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYE2_NOVAD
Sequence: MASATDTVSAGSTPRDKVVTRFAPSPTGFLHIGGARTALFNWLYARHHGGTYLLRIEDTDRARSTDAAIDAIFDGLEWLGLGGDEPAVFQFARSDRHAEVAHKLLEAGHAYRCYLTQEELAARRELAQAERRPFRIDSEWRDATPDQWPADQSYVVRMKAPREGETTIVDKVQGSITVQNSELDDFIILRSDGTPTYMLAVVVDDHDMGVTHVIRGDDHINNAFRQLVIIRGMHAIEGGWPDPVYAHIPLIHGADGAKLSKRHGALGVDAYRDEMGLLPEAVFNYLLRLGWGHGDEEIISREQAVAWFDIGDVNKGASRFDLKKLLNLNGHYIREADDARLAALVAPRLATLAPGFAPDKGLDLLTRAMPVLKVRAADINELAAGSVFLFAQRPLAMAEKAASLLTDDARAILTKVAGVLEAENVWTTGVLEATVKQMAEELGIGLGKIAQPLRASLTGQTTSPGIFDVLALLGKDESLSRIRDQAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_MYCBT
Sequence: MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: FITM2_DANRE
Sequence: MAAAVAGSLVDKLVCLWRQPYTRIYLPHLFFCISLVGSVLKNAELVPESYFSSSRNVLNLYFVKVSWGWTIVLLLPFIAYSNFYIKSHMFALRRLTSLLVATLVWYICTETFFYIEDITGSCYESNTMVVIRGEFDTKAACRKAGFFWDGFDISGHSFILSYSSLVIMEEMVPMLHIQPAYRNPPLDCLYLALNVIVAIWIWMFGCTSVYFHDIIDKILGTSCGILGWYMTYKVWYVKLFSPGLPPQPKQHT
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen (By similarity).  This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (PubMed:18160536) (By similarity).  Required for lipid droplet accumulation in liver and intestine during embryogenesis (PubMed:18160536).  May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity).  May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity).  May play a role in the regulation of cell morphology, ER morphology and cytoskeletal organization (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase FITM2, Fat storage-inducing transmembrane protein 2, Fat-inducing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FIT family. FIT2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LSRG_YERPP
Sequence: MHVTLVEINVKEDKVDQFIEVFRANHLGSIREAGNLRFDVLRDEHIPTRFYIYEAYTDEAAVAIHKTTPHYLQCVEQLAPLMTGPRKKTVFIGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_ERYLH
Sequence: MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFKELGPDAKGGVRLAKSIEDVEASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYLSMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITIDPAQGFMPHHGRAVAFALKLSGDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVEEMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVGGGATTEKVTAAFKIILKDPAVEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLEGTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ZAPB_SHIF8
Sequence: MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: RL29_MYCGI
Sequence: MAVGTTTGELRELSDDELTDKLRESKEELFNLRFQMATGQLANNRRLRVVRQEIARVYTVLRERELGLAAGPGGEDS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PEPT_YERPY
Sequence: MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATRYHQELPVDETPEYTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKES
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_YERPS
Sequence: MTDKSTARKKITRIGIGGPVGSGKTAIIEVITPILIKRGIKPLIITNDIVTTEDAKQVKRTLKGILDEEKILGVETGACPHTAVREDPSMNIAAVEEMEERFPESDLIMIESGGDNLTLTFSPALADFYIYVIDVAEGEKIPRKNGPGLVQADILVINKIDLAPYVGASLDVMESDTKVVRGNRPYILTNCKTGQGIEELVDMIMRDFLFTHVQPEGEQA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THAB_XENLA
Sequence: MDQNLSGLDCLSEPDEKRWPDGKRKRKNSQCMGKSGMSGDSLVSLPPAGYIPSYLDKDEPCVVCSDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEENRVRRRKEEMIKTLQQRPEPSSEEWELIRIVTEAHRSTNAQGSHWKQRRKFLPEDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELTCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGRSLAAFNLDDTEVALLQAVLLMSSDRTGLICTDKIEKCQETYLLAFEHYINHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV
What is the function of this protein?
High affinity receptor for triiodothyronine (T3).
What are the official names of this protein?
Thyroid hormone receptor alpha-B, TRalphaB, Nuclear receptor subfamily 1 group A member 1-B.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBR_PHYPA
Sequence: MERAGPVLREVKVRSHRQSSLMSESVKQADIEDSQVFCKQEPVEDNIESGYETPTKSSRAGLGDKTPNGGDIKPRKKAWSPVYLEGLEGRFREHCEVGLCLDDPTLQQALRLFKESKPLLLANIDSIGTSTVEDTERLWGGCVLYVVKALSCGATVDGDKSESNAVGFTLSQLMRQTKIRHARELDMISICAITECLLELPHFLVKVGPIVKQMYGDEWEKRLQVKEVQANFVHLTALFTYFKRVYQDFFLSPDTFTNIVSRSLSGVRDEHHVSVHMQFGWMLFLALRMHVIQQFSDLVTCTNALMAVMFCEPLSGAWSKSNLGFCFFVFMQVILILHMPPDLRKFSLQDPVRFAKRSSEGVDLVASLCATYYAADEDVSSLLEKANATISKLFGKPMKGGLAYLEGLMDKKSLAANLRMLEKDYEDSYQSRGGLDERMFINGEDGLLGTLSNESPRFSGSKVLFLVPSLHVDECKVKSSFPLTNVPVYQRKFDIMASPVRFGAFSMGAAPSSPAASPWSSPVKHMGTQGSSGGKRPPSTPVTITMTTAKWLRTVITPLAAEPSVELQLFFRSCDRDISADVKNRAHVLLDLIFSAERGGGWQGVAGLMDVWPEQRKLEAIKLYYKVLGAMCRSEEQRLHTHNLTSLLSNERFHRCMIACSAELVLATHKTVTMGFPAVLEPAGITAFDLSKVIEYFVRHEETLPRELKRHLNTIEERILESMAWEKGSSMYNSLIVARPSLANEINRLCLLADPMPALENLATQVRPATVMHRIPGLSKSGHSGEVACAAHTPTSASSPPQNGSSTSEAGFLSPVKDRPSAFSAFSSPMRNRLRAPLQSAFASPQRPSPLGGGETCADTVINVFFQKALVLAAVRIRTVCERIGQPQHLIERVYKVFQHALHHETSLFFNRHIDQLVLCTIYGVCKKPSYSVSGFRSYRHSCDMAMRMTLWINFQKTGGLESGDIIKFYNDVFVHVTKKFLVQVDTNSSMRSPRKAHGSDGNDGTISKLLKDEMEVIIIKGEAPGSPVASIFSTFPDISPKKVSALHNVFVSPLRSSKVDKLMSPRTRTLYACVGESTRDYQSPSKDLTAINNRLNKRFIAHGDLAGWTLKTDPQ
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL33_PARL1
Sequence: MAKPASIKIKLESTADTGYFYVTKKNSRTMTEKMVIKKYDPIARKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS18_SHESW
Sequence: MARYFRRRKFCRFTAEGVAEIDYKDIVTLKNYITESGKIVPSRITGTSAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MRAY_CLOTE
Sequence: MNSKIIYSVLVAFFISIITGPILIPLLHKLKFGQNIREEGPKSHQKKAGTPTMGGIIFILATIISMFILIKNPSDEAMFAMYAFIAFGVIGFIDDYLKIARKNNLGLKAKQKMVLLLIVSFAFAYYGANNPEIGTSIIIPFSEKTLDFGIFYIPFIILYFAATTNAVNLTDGLDGLATSITILVMTFFVIVSFNMGHYTLSVFCAVTAGALLGFLKYNAFPAQIFMGDTGSLALGGAVAAVAMILKLPLVVIIVGGIYVLETLSVIIQVISFKLTGKRVFKMSPLHHHFELCGWHETKVVSVFSIVTVILCMIAFLSFK
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.