PharMolix/UniProtQA huggingface dataset:
Protein: NSS_AINOV
Sequence: MFLNGISLRLTRRSGMWHLLLNMGPNSISIPLDSSSSIRRRPRWYSVRRHNQVLILHLVASSLHWLITIFPNTQQILCQTLPSLSIVSQDI
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus NS-S protein family.
Protein: SYM_BLOPB
Sequence: MTTKKMLVTCALPYANGSLHIGHMLEHIQADIWVRYQRMQGNCVYFICADDAHGTAIMLKSQQLNIAPEQMIAQIRQEHQRDCYKFGISYDNYYSTHSDETRELLHDIYSRLNTRGFIKSKFISQLYDSKKNMFLPDRFVKGICPKCKKDDQYGDNCAACGTIYTSLELINPKSVISGTSPIIRKSEHLFFDLPAFTDTLRTWIRSGSIQKEVANKVEEWFKLGLKKWDISRDAPYFGFKIPNSSEKYFYVWMDAPVGYMGTFKNLCKKNKNISFNDFWGSNSKTDLYHFIGKDIIYFHCLFWPAVLSGSQFRKPTNIFVHGHVTLNGSKISKSKGTCINVSTYLSCLNPDYLRYYYATKLSSHANDIDLNLSDFITRVNSDIINKILNLASRNSGFIHQYYNGHLSNTLTHPLIYNMFIESRHYIGKLFQKREFNYAMREIMKLADEANRYIDKHAPWHIAKKIDRRQEALSIYSMGIQLFRVLMIYLKPVLPKLANYSECFLNTRLTWGSLSAPLSNHRINKFKIIFSRIHPDQIASMTNKSQLHERLTDNNV
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML18_ORYSJ
Sequence: MPMAELEQVFRRYDANGDGKISAEELASVLRALGAPLGPGEVRRMMDEMDSDRDGFVDLSEFAAFHCGPTPAHGGKGGDAKDQEAASEAELREAFRMYDADSNGKISARELHRVLRQLGDKCSVADCSRMIRSVDADGDGCVNFDEFKKMMGGGGGRR
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML18, Calmodulin-like protein 18.
Protein: PXPA_SHIBS
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSTFAEKEIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RAB3C_RAT
Sequence: MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQSTRLKETPPPPQPNCGC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: YAYG_SCHPO
Sequence: MKRCRSEHVPSRLPRKKCKNHLDMRSFLSLFASKKSNAHDASSIVLNEKVNFVTDNDHLPSSTGVCEFCDNVLYLSTCDRCQRNICRNCSTLMYFKENTVARCLDCL
What are the official names of this protein?
Uncharacterized protein C4H3.16.
Protein: RSMA_BURO1
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDSIVATIGPARGQRMVEIGPGLGALTGPLIERLATPESPLHAVELDRDLIGRLQQRFGALLELHAGDALAFDFRSLAAPGDKPSLRIVGNLPYNISSPLLFHLMTFADAVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMEKMLDVPPESFQPPPKVDSAIVRMIPYEPHELPDVDPVLLGEIVTAAFSQRRKMLRNTLGDYRETIDFDALGFDLARRAEDVSVAEYVGVAQALAALRKAG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
Protein: HPM1_HYPSB
Sequence: MAVLPQVDLGHLANRDTAFVIVGAFFAWVFVVNPIYLLYFHPLSKFPGPKFWAVTRWGVSLAIISGKSHDIILDLHKKYGPILRIAPDELAFQSVSAWNDIGGHRKPGQPEMTKEPIFNEAFKDNLLGVTTREDHSRMRRILSRGFSAATFQKQEPLLKGYVDLLLSELRKRCEGGQKLIDIQTWYSFTAFDIIGDLTFGESFGSLDSGGHHPWASLIFETTRFVILANCLKRINRAFLPVLLFITPKGFGRRLKENQQLTDAKIAKRRALGASRPDYMTAMLGNDEKGAKLSDTEITSNCTALILGGAETISSALSGTTYYLTKNPEAMAKVIEEVRSAFSSEDEITLTGTGHLKYLNAVITESLRMFPPFAGASPRQVPRGGATIAGEFIPAGTSVGIWHWSMARCPDFFTHANEFHPERWLDDPRFDNDKKDASQPFAVGPRNCIGMNLTYVELRLILARLFWNFDIKLDKSCDNWVDDMVEYFGWEKIPLMVSLTPRS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of hypothemycin, a resorcylic acid lactone (RAL) that irreversibly inhibits a subset of protein kinases with a conserved cysteine in the ATP binding site such as human ERK2 (PubMed:18567690).  The first step is performed by both PKSs hmp3 and hmp8 and leads to the production of 7',8'-dehydrozearalenol (DHZ) (PubMed:18567690, PubMed:20222707).  The highly reducing PKS hpm8 synthesizes the reduced hexaketide (7S,11S,2E,8E)-7,11-dihydroxy-dodeca-2,8-dienoate, which is transferred downstream to the non-reducing PKS hpm3 (PubMed:20222707).  Hpm3 then extends the reduced hexaketide to a nonaketide, after which regioselective cyclization and macrolactonization affords DHZ (PubMed:20222707).  The next step is the conversion of DHZ into aigialomycin C and is performed by the O-methyltransferase hmp5, the FAD-binding monooxygenase hmp7, and the cytochrome P450 monooxygenase hmp1 (PubMed:18567690).  The wide substrate tolerance of the hmp5 and hmp7 implies that the reactions from DHZ to aigialomycin C can occur in any order (PubMed:18567690).  The steps from aigialomycin C to hypothemycin are less well established (PubMed:18567690).  The FAD-linked oxidoreductase hmp9 presumably catalyzes oxidation of the C-6' hydroxyl to a ketone (PubMed:18567690).  The timing of this oxidation is important, since the resulting enone functional group is a Michael acceptor that can react spontaneously with glutathione, an abundant metabolite in fungal cells (PubMed:18567690).  The glutathione S-transferase hmp2 catalyzes cis-trans isomerization of the 7',8' double bond with equilibrium favoring the trans isomer (PubMed:18567690).  The hpm6-encoded transporter might preferentially pump hypothemycin out of the cell relative to the trans isomer aigialomycin A.  The cis-to-trans isomerization may be coupled with C-4' hydroxylation, since all known hypothemycin analogs containing the enone functional group also have hydroxyl groups at both C-4' and C-5' (PubMed:18567690).
What are the official names of this protein?
Cytochrome P450 monooxygenase hmp1, Hypothemycin biosynthesis cluster protein hpm1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACP_CYLSN
Sequence: MSDTLKRLQKIVSEQLSVDPEKVTSTADFGKQLGADSLDIIELIMTIEYEFNIDIEDHYASKITTVQDALNYIENKIKQK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARCD_SHIFL
Sequence: MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWGITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSYLVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVATLAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAVVVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEMMGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASLWLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVGACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIASVPATWMLVG
What is the function of this protein?
Catalyzes electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway.
What are the official names of this protein?
Putative arginine/ornithine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C91_GEMDI
Sequence: MMAKLMITVMMVLLLSLQQGADGRSERWRKNQMAASRIMRNLITARGDPPRFCVHKICYEDSECNQWCTGGCNPTQGKCDTA
What are the official names of this protein?
Turripeptide Gdm9.1.
What is the protein family that this protein belongs to?
Belongs to the Pg turripeptide superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_CLOPE
Sequence: MELIIATRKSKLAQVQTEKVMELLKGKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVKEIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGARIGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVISDYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSLIGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILEEV
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: FOLD_ROSCS
Sequence: MTAMILDGRALAKTLREELRADIQAFVQTTGVTPSLAVVKIAGDPASERYTRTIRKGCEDIGIVFYDHTLPPDTTQAALEETLHALSFDRAVNGILLHLPLPPGFDSNRAIAQIDPHKDVDGVHPYNAGLLAMGQPTMVPNTPAGGMELLLRNHILIKGQRATVVGRSVVVGKPMALLLLQEHATVTIAHSRTKDLASVVREADIVVAATGKPGLITADMVRPGAVVVDFGVNVLGDGKVVGDVDFAGVAEIASAITPVPGGTGPVTNIMLLRNVLRAARLQGVGRGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ATG8D_ORYSJ
Sequence: MKPRPFKEEFTLEERAKESAAMIASYPDRIPVIVEKFSRSNLPEMEKRKYLVPCNMPVGQFIFILRSRLHLSPGTALFVFVNNTLPQTAQLMGSVYESYKDEGDGFLYLCYSSEKTFG
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8D, Autophagy-related ubiquitin-like modifier ATG8D.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: CITD_HALOH
Sequence: MEIKRTASAGTMESSDIMITVKPSNNGIKIELKSDVEKQFGNQVKKIIKNTIEGMGVKNVYIRAQDRGALDYAIKARTRTALERASKGAEEIEK
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_SULTO
Sequence: MTDVLVVVKVFPESDEVNLDNLYEEIGKKLPAGYKLVRKETEPIAYGLKALIAYVQMPENVEGGTDTLEEIINSIQGVSHAEVVGITRLGF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: HIS3_STRTD
Sequence: MTEVKLDFDKQGGLVPVIVTDYKTGQVLMLAYMNEVSYQLTLETKQMHYWSRSRNELWHKGATSGHFQHVKSIKTDCDWDTLLIAVEQEGAACHTGAYSCFFTDIYDDNQDR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_HYSAF
Sequence: MTNIRKSHPLLKIINHSFIDLPTPSNISTWWNFGSLLGACLIIQILTGLFLAMHYTAYTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLYLHVGRGLYYGSYMFTETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFSLPFIITALVLVHLLFLHETGSNNPSGIDSNSDKIPFHPYYTIKDILGLLLMLTALLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRSMLFRPFSQCLFWILAANLLILTWIGGQPVEHPYITIGQLASISYFSILLIIMPLTSIMENKLLKWRVLVV
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: 3MGH_PSEU2
Sequence: MPTALPDHFFHRDAQVLARDLLGKVIRHKAGDLWLAARIIETEAYYCAEKGSHASLGYTEKRKALFLDGGHIYMYYARGGDSLNFSAEGPGNAVLIKSAFAWTDATSDENALAQMQLNNPDASGAMRPAQRLCAGQTLLCKALGLKVPVWDAKRFDPQKLLVEDVGQTPERIIQTTRLGIPAGRDEHLMYRFVDAGYARFCTRNPLRRGQVEGRDYLFLDQGN
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RS12_CERS5
Sequence: MPTIQQLIRKPREPKRVRSKSQHLESCPQKRGVCTRVYTTTPKKPNSAMRKVAKVRLTNGFEVISYIPGEKHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRRQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DTD_STAA1
Sequence: MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_ECO24
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSIDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CDPK5_SOLTU
Sequence: MGNACRGSFGGKTFQGYPQPQDHSESNSNPKHNSDSPKPKKEQQPLVTMNRTSTNQSYYVLGHKTPNIRDLYTLGRKLGQGQFGTTYLCTELSSGIDYACKSIAKRKLISKEDVEDVRREIQIMHHLAGHKNIVSIKGAYEDPLYVHIVMELCGGGELFDRIIQRGHYTERKAADLTKIIVGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFTDVVGSPYYVAPEVLLKHYGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGHIDFDSDPWPLLSESAKDLIRKMLCMRPSERLTAHEVLCHPWICENGVAPDRALDPAVLSRLKHFSAMNKLKKMALRVIAESLSEEEIAGLKEMFKAMDTDNSGAITFDELKAGLRKYGSTLKDIEIRELMDAADVDNSGTIDYGEFIAATIHLNKLDREEHLMAAFQYFDKDGSGYITVDELQQACADHNITDVFFEDIIREVDQDNDGRIDYGEFVAMMQKGNPCIGRRTMRNSLNFSMRDAPGAH
What is the function of this protein?
Regulates the production of reactive oxygen species (ROS) by NADPH oxidase.
What are the official names of this protein?
Calcium-dependent protein kinase 5, CDPK 5, StCDPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PYRH_RHOPB
Sequence: MGEPVYRRVVIKLSGEYFAGDQSFGIDQPTIDRIAGDLIAAQKLGVEIAVVVGGGNIFRGVEVSSRGVSRPTGDTMGMLATVMNCLALEAAIERRAVAARTLSAFVMPQVCELFTRGAAHRYLAEGKIVLLAGGTGNPFFTTDTTAVLRAGEIGAQAVLKATNVDGVYSADPKKDPSAQRFERLSHSQALEGGYKVMDATAFALARETSLPIIVFSIAEAGSIGAILSGTGRGTVVAG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPT2_DROME
Sequence: MRLRLQVLVALLTCSSISVSLAYKPVVILHGILSGAESMASLVREIEEFHPGTIVYNCDKFNGWYSLENAWRQVDQVRDYLNEVGKLHPEGIIVLGYSQGGLLARAAIQSLPEHNVKTFISLSSPQAGQYGTSFLHLIFPDLAAKTAFELFYSRVGQHTSVGGYWNDPQRQDLYLKYSEFLPLINNEKKTSNSTSFKMGMVRLNKLVMIGGPNDDVITPWQSSHFGYFDENMDVIPFIRRPIFTSDSIGIRTLQEAGKLIIVVKPHVHHLAWHTRRDVIHEVIFPYLD
What is the function of this protein?
Probable thioesterase removing fatty acyl groups from various substrates such as S-palmitoyl-CoA.  Because of structural constraints, may be unable to remove palmitate from peptides or proteins (By similarity).
What are the official names of this protein?
Lysosomal thioesterase PPT2 homolog, PPT-2.
What is the protein family that this protein belongs to?
Belongs to the palmitoyl-protein thioesterase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: CYB_CHAFL
Sequence: MTILRKSHPLMKMVNHAFIDLPAPSNISGWWNFGSLLGMCLIIQIASGLFLAMHYTSDTISAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIVLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSSLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSNTDKIPFHPYYTFKDFLGVIIILALFLTFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLLVLTWIGGQPVEPPFIIIGQVASILYFSIILVLLPVAGLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OVCA2_XENTR
Sequence: MAATETPGAAQKRVLRVLALHGYRQNERSFWERTGALRKRLRGRADLITFSAPLLVPDPDAEPGAGDPDSLQDESRGWWFSNPEQNSFDAMEESKTCSGLEAPLDTVAKAFSELGPFDGILGFSQGAALVAIICALKQQGDPRFHFDFAILVAGFKSLSTDHAKHYQQPITVPSLHVIGETDRVISAAMSQELVSHFENPVILMHSGGHYVPACAPQKKVYWEFLDKFLT
What are the official names of this protein?
Esterase OVCA2, Ovarian cancer-associated gene 2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: IDM2_ARATH
Sequence: MSDTMPEIVSPLVAENSQEQEESVLISLDIEEDKLFLLHFIIGTYFGPDLRKQHHRPKQSAFQIQALKNVVVDELSGSLMKRAELERVYYHIIRNVDPSLVMKPKKLREYFNAKRNDSNRDYPLFVDLFPRKLHPETHVRHKFKFIRSIVFINDPDTSCMREECVARFKRLTGLDSFALSLSVDVTKSNGVVAANEVKVEIDESVEPVKEDNAGTCTSGEESDVAAKPEVKSEAHGGLMVGLMDIGECDDAYLFRVSLPGVKRDERYFSCEVEDNGKVLVRGVTTTGGKRVKRYSHVFEMQTRSLCPPGNFSVSFRLPGPVHPHEFSGNFGTDGILEGVVMKNLQKQTV
What is the function of this protein?
Prevents DNA hypermethylation and transcriptional silencing of transgenes and of some endogenous genes (PubMed:25002145, PubMed:24920332).  May act as a molecular chaperone of IDM1, regulating its H3K18 acetylation activity (PubMed:25002145, PubMed:24920332).
What are the official names of this protein?
Increased DNA methylation 2, Alpha-crystallin domain-containing protein 39.4, AtAcd39.4, Protein ROS5, Repressor of silencing 5.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Colocalizes with IDM1 within nucleoplasmic and nucleolar foci.
Protein: FARNS_PICXS
Sequence: MASVDQSQLCSKSVSMSLSVDDGVQRRTGDYHSNLWDDDFIQSLSTPYGAPCYRERAERLIGEVKEMFNSVRLSPLNDLLQGLSMVDSVERLGIDRHFKNEIKSALDYVYSYWSEKGIGCGRESVVTDLNSSALGFRALRLHGYPVSSDVFKDQNGQFACSANTQTEGEMRGVLNLFRASLVAFPGEKVMEDAERFSAIYLKEALKTVPICSGSLSGEIEYVLEYGWLTNFPRLEARNYIDIFGKDTSPCLQTEKLLELAKLEFNIFHSLQQRELKQVSRWWKDSGFSQLTFTRHRHVEFYTLASCIAIEPKHSAFRLGFAKLCYLGIVLDDIYDTFGTMDELELFTAAIKRWDPSATECLPEYMKGVYMVFYECVNQMAREAEKTQGRDTLSYARNTWEAVFDAFLEEAKWISSGYIPTFEEYLENGKVSFGYRAATLQPILTLDVPLPLHILQEIDFPSRFNDLAASILRLRGDVCGYKAERSRGEEASSISCYMKDNPGATEEDALNQIDTMIKEKIKELNWEFLKPDSNVPISSKKHAFDILRAFYHLYKYRDGFSIANNETKSLVMRTLLETVPF
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of sesquiterpene and monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to (3E,6E)-alpha-farnesene and of (2E)-geranyl diphosphate (GPP) to (E)-beta-ocimene (PubMed:21385377).
What are the official names of this protein?
(E,E)-alpha-farnesene synthase, (E)-beta-ocimene synthase, Terpene synthase TPS-Far/Oci, PgxeTPS-Far/Oci.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
Protein: ISPG_BURP6
Sequence: MFGGHAPRRVSHAVDVRWGGTLVTIGGAAPVRVQSMTNTDTADAIGTAIQVKELANAGSELVRITVNTPEAAAAVPAIREQLDRMGVTVPLVGDFHYNGHLLLRDYPDCAQALSKYRINPGNVGQGAKRDSQFAQMIEAAIKYDKPVRIGVNWGSLDQDLLARMMDENGARAEPWEAQSVMYEALIQSAIGSAERAVELGLGRDKIVLSCKVSGVQDLVAVYRELSRRCGFALHLGLTEAGMGSKGIVASTAAIGLLLQEGIGDTIRISLTPEPGAPRTGEVVVGQEILQTMGLRSFAPMVVACPGCGRTTSTLFQELALRIQTYLREQMPVWRSEYPGVEKMNVAVMGCIVNGPGESKHANIGISLPGSGENPAAPVFVDGEKVKTLRGEHIAEEFQQIVSDYVARTYGRATAQN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.