PharMolix/UniProtQA huggingface dataset:
Protein: SPD2B_HUMAN
Sequence: MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQNAVGREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSKDWKGSKDVLRKASSDMSASAGYEEISDPDMEEKPSLPPRKESIIKSEGELLERERERQRTEQLRGPTPKPPGVILPMMPAKHIPPARDSRRPEPKPDKSRLFQLKNDMGLECGHKVLAKEVKKPNLRPISKSKTDLPEEKPDATPQNPFLKSRPQVRPKPAPSPKTEPPQGEDQVDICNLRSKLRPAKSQDKSLLDGEGPQAVGGQDVAFSRSFLPGEGPGRAQDRTGKQDGLSPKEISCRAPPRPAKTTDPVSKSVPVPLQEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPFLSNSLGGQDDTRGKGSLGPWGTGKIGENREKAAAASVPNADGLKDSLYVAVADFEGDKDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP
What is the function of this protein?
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation.  Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides.  Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization.  Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).
What are the official names of this protein?
SH3 and PX domain-containing protein 2B, Adapter protein HOFI, Factor for adipocyte differentiation 49, Tyrosine kinase substrate with four SH3 domains.
What is the protein family that this protein belongs to?
Belongs to the SH3PXD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells.
Protein: PURL_STAA8
Sequence: MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS4_PYRPY
Sequence: MGITGMTYMFTMVLSLIVLIFSASTVGFDYFQFTQQYQPAVCNSNPTPCNDPTDKLFTVHGLWPSNRNGPDPEKCKTTTMNSQKIGNMTAQLEIIWPNVLNRSDHVGFWEREWLKHGTCGYPTIKDDMHYLKTVIKMYITQKQNVSAILSKATIQPNGNNRSLVDIENAIRSGNNNTKPKFKCQKNTRTTTELVEVTLCSNRDLTKFINCPHGPPKGSRYFCPANVKY
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species, self-incompatibility is controlled by the single, multiallelic locus S.
What are the official names of this protein?
Ribonuclease S-4, S4-RNase.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GATA_CHLT2
Sequence: MYRKSALELRDAVVNRELSVTAITEYFYHRIESHDEQIGAFLSLCKERALLRASRIDDKLAKGDPIGLLAGIPIGVKDNIHITGVKTTCASKMLENFVAPFDSTVVRRIEMEDGILLGKLNMDEFAMGSTTRYSAFHPTNNPWDLERVPGGSSGGSAAAVSARFCPIALGSDTGGSIRQPAAFCGVVGFKPSYGAVSRYGLVAFGSSLDQIGPLTTVVEDVALAMDAFAGRDPKDSTTRDFFKGTFSQALSLEVPKLIGVPRGFLDGLQEDCKENFFEALAVMEREGSRIIDVDLSVLKHAVPVYYIVASAEAATNLARFDGVRYGHRCAQADNMHEMYARSRKEGFGKEVTRRILLGNYVLSAERQNIFYKKGMAVRARLIDAFQAAFERCDVIAMPVCATPAIRDQDVLDPVSLYLQDIYTVAVNLAYLPAISVPSGLSKEGLPLGVQFIGERGSDQQICQVGYSFQEHSQIKQLYPKAVNGLFDGGIE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SLYA_ECO57
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: SARX_STAAN
Sequence: MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
What is the function of this protein?
Involved in the regulation of virulence genes.  Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb.  Binds directly to the agr promoter region (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarX, Staphylococcal accessory regulator X.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC149_BOVIN
Sequence: MANQLRERHQSLKKKYRELIDGDPSLPPEKRKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNKLLRMTIAKQRLGDEEIGVRHFAAHEREDLVQQLERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERLNQELNHILSGHENRIIDVDALCMENRYLQERLKQLHEEVNLLKSNIAKYKNALERRKNSKGQNKSSSSALTGVLSAKQVQDLLSEDHGCSLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNKILGNRVAELEKKLRTLEVSGLWSLPGLSYNVSIGFGSMFFLKYLCLWLIAVH
What are the official names of this protein?
Coiled-coil domain-containing protein 149.
What is the protein family that this protein belongs to?
Belongs to the CCDC149 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LSPA_CLOTE
Sequence: MEIIIIVLGIILDRVTKLWAIKRLSIGEDIVVIKDFFSFSYLENRGAAFGIFKDKQLFLISITMVAILLMMFYLFINKTNPKILKISLSLIISGAIGNLIDRIKYRYVVDFIFFHYKDKYHFPIFNIADVLVSLGTILLIIFIIKEDGYEDRKIFS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSX_PSE14
Sequence: MSAPIIAIDAMGGDFGPRNIVQASLACLTATPSLHLVLVGQASLIEELIARHGAVDRSRLRVVNANEAIAMDERPSQALRGKPDSSMRVALELVASGQAQACVSAGNTGALMALSRFVLKTLPGIDRPAMIAAIPTRSGHCQMLDLGANVDCSAEALYQFAVMGSVLAETLGVKKPRVALLNVGTEDIKGNQQVKLAAGLLQAAQGLNYIGYIEGDGLYRGEADVVVCDGFVGNVLLKSSEGLASMIAARIDTLFNRNLLSRAVGALALPLLKRLQTDLAPARHNGASLLGLQGIVVKSHGSASVSGFQSAIQRAIVESRENLPQRLKGRLELLLQNGQT
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SYL_ESCF3
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_ENTFA
Sequence: MAEEKYIMAIDQGTTSSRAIIFDKKGNKIGSSQKEFTQYFPNAGWVEHNANEIWNSVQSVIAGSLIESGVKPTDIAGIGITNQRETTVVWDKATGLPIYNAIVWQSRQTTPIADQLKEDGYSEMIHEKTGLIIDAYFSATKVRWILDHVEGAQERAENGELMFGTIDTWLVWKLTGDTHVTDYSNASRTMLFNIHDLDWDQEILDLLNIPRVMLPKVVSNSEVYGLTKNYHFYGSEVPIAGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNTGEEPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSAIQWLRDGLKMLQTAAESEAVAKASTGHNEVYVVPAFTGLGAPYWDSQARGAVFGLTRGTTREDFVKATLQAVAYQVRDIIDTMKEDTGIDIPVLKVDGGAANNDFLMQFQADILNTAVQRAHNLETTALGAAFLAGLAVGFWKDLEEIKAFQEEGQQFEPIMAEEEREDLYEGWQQAVAATQQFKRKNK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: YET3_YEAST
Sequence: MSLYYTLVFAILVVEIFMFSILALPIPSRYRRPLTLLLLKPFKSSTVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFFAQRNMYLTGITLFLTFVVVRTFGLVIELLTMKDIYRASPPVASSDVKKNDSVTAEAAAQSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN
What is the function of this protein?
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.  May be involved in invertase secretion.
What are the official names of this protein?
Endoplasmic reticulum transmembrane protein 3.
What is the protein family that this protein belongs to?
Belongs to the BCAP29/BCAP31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYSH_ECOSE
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RQSIM_ARATH
Sequence: MDLSSDQLVMKIVEMGFEKLDALEAVKAVGGKSCDDAVEYILKGNHRTGGFKPASLLCSSGSNKILGKRAMPSSFSSSESKRQSSLLDHFRSVNQNKKKGDTFGTVEVDSQLETVSEHSEEVRKSLAPVFMESSCFPEGQLLNGCSEASSSWEKRVNSILRNRFGISSLRSFQREALSTWVAHKDCLVLAATGSGKSLCFQIPALLTGKVVVVISPLISLMHDQCLKLSRHKVSACFLGSGQLDNCIEEKAMQGMYQIIYVCPETVVRLIKPLQKLAKTHGIALFAIDEAHCVSKWGHDFRPHYRKLSVLRENFCASNLEFLEYDVPIMALTATATVNVQEDILESLHLSKETKIVLTSFFRPNLQFSVKHSRTKFASSYAKDFQNLVDLYSEKKNSTGKKLAVISRESEEQTDFGSHDSENIHETDYDEDEEDQENSLAKKNSSNGKELSEAYLEDETDIFQSVDDWDVACGEFCAMPSCELLEIPVPSEKQKDLEGLTIIYVPTRKESVNIAKYLCGVGLKAAAYNASLPKKHLRQVHQDFHDNKLQVVVATIAFGMGIDKKNVRKIIHYGWLQSLEAYYQEAGRAGRDGELAECVLYADLSRAPTLLPSRRSKEQTEQAYKMLSDCFRYGMNTSQCRAKILVEYFGEEFSSKKCNSCDVCTEGPPELVDVREEANLLFQVITAFHLQVDNDSEHAPYEDYGLGNSKQNKLSHKPNLLFFISKLREQCEKFKETDCLWWKGLARIMEAEGYIKEMDNKDRRVEIKFIQPTEKGKKQLDFQDDKPLYVYPEADMLLSLKQDRTYSGFSEWGKGWADPEIRRQRLERRERKPRRERKPRKKRTRGRSSTKLHPWRSKE
What is the function of this protein?
Plant specific 3'-5' DNA helicase that may play a role in the repair of DNA.
What are the official names of this protein?
ATP-dependent DNA helicase Q-like SIM, RecQ-like protein SIM, AtRecQsim, Similar to RecQ protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDUB7_GORGO
Sequence: MGAHLVRRYLGDASVEPDPLQMPTFPPDYGFPERKEREMVATQQEMMDAQLRLQLRDYCAHYLIRLLKCKRDSFPNFLACKQERHDWDYCEHRDYVMRMKEFERERRLLQRKKRREKKAAELAKGQGPGEVDPKVAL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, Complex I-B18, CI-B18, NADH-ubiquinone oxidoreductase B18 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB7 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: SYR_LACLM
Sequence: MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGEIAEKIDTKGFEKVIAVGPYVNFFLDKNATASEVIREVLAEGEHYGDANIGEGGNVPIDMSAPNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLGDWGKQFGLLITAYKKYGDEATITANPIDELLKLYVKINAEAKEDSEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEFNRIYGKLGVTFDHFMGESFYSDKMDAIVEDLENKNLLHESKGALIVDLEKYNLNPALIKKTDGATLYITRDLATAAYRKKTFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHVPFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAKNPNLENKEEVAKQVGVGAVKFYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVNIDNISLVVSDAEAWEIVKALKEFPNIVKRAADNYEPSIIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLALISATSIVLKEALRLLGVAAPENM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJV1_SCHPO
Sequence: MDSIEKTPDGEEEEKDVWDTALEKGGCVEEHLRLNDCYWDTHDWRKCTEQMEEFRKCWEKRHGPLPSISDKKNKNLS
What are the official names of this protein?
Coiled-coil-helix-coiled-coil-helix domain-containing protein C550.01c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUOD_ALKEH
Sequence: MREFKSYTVNFGPQHPAAHGVLRMVLEMEGETVRRADPHIGLLHRATEKLAESKPYNQSIGYMDRLDYVSMLCNEHAYVMAIEKLLGIEAPIRAQYIRVMFDEITRILNHLMWLGAHGLDVGAMTAFLYCFREREDLMDCYEAVSGARMHAAYYRPGGVYRDLPESMPKYEPSKFRSKKELELMNAARQGTMLDFIEDFTERFPGCVDEYETLLTENRIWRQRLVDVGVVSPERALQLGFSGPMLRGSGIEWDLRKKQPYDVYDRVEFDIPVGTNGDCYDRYLVRIEEMRQSNRIIKQCVDWLRHNPGPVMLEDHKVAPPSREEMKDDMESLIHHFKLFTEGYTTPPGEVYAAVEAPKGEFGCYMISDGANKPYRVKLRAPGFAHLSAMDEMARGHMLADVVAIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PAN3_CHAGB
Sequence: MAATRYPPNDLRRQVGSPRSKGRENKDTLCRNILIYGNCRYEDQGCTFNHDQNKNPSPQADFSKKTFNVDSPAFTPSSQPQVLAKKTTLSSQAANAAPFTPRGAGTPNLQQTAEASVFNPAAIREFTPQNYDIGNTNSNGVPQENGIYSDPFTTMGSLGSTLPSAGQYNLYASDHNSLGGPGAQFYPQHGSFPAGPLQPPNYHLYQPHDSYRQELQPWQRATYDFFIPAKMREELQKKMFATQQVMPNSGLPQLERWHSLFPLDTNNRKNTSSFGYPSWVYKAQNSRTARHYALRRLEGYRLTNEKAILTVMKEWKKIKNGNVVTVHEAFTTREFGDSSLIFAYDYHPLSKTLQEHHLQPTHGNRYRAPSAVPENVLWGYICQITNALKTIHSNKLAARCLEPSKIILSDNNRIRLSACSILDVVQFESNTKSVAELQQEDLVKFGKLILALATGAPPAHLNNIQVALDSLVTKYSANLKDAVAWLIAPSNPGESKSIENFISGIATHMTAFFDLALQDGDEKQFHLARELENGRIARSMMKLMTIIERAEPGGAQSWSETGERYQLKLFRDYVFHRVEADGKPNLAVGHMLSCLSKLDAGIDEMVVLTSRDNETVFVLSYRELKQMFDRAFNELVKHSKTGAPGANN
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_YERPE
Sequence: MADKSDLNALSGRFRGYYPVVIDVETAGFNAQSDALLEIAAVTLQMNKEGWLLPDETLHFHVEPFEGANLQPEALAFNGIDPTNPLRGAVSEHDALHAIFKAVRKGIKDKGCNRAIIVAHNANFDHSFVMAAAERASLKRNPFHPFATFDTAALSGLVLGQTVLAKACLAAGIPFDSSQAHSALYDTLQTAKLFCELVNRWKKLGGWPLPAAESG
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: RIMM_WOLPP
Sequence: MNICLGIITSPHGIKGAVKIKTFTEKPENIFLYGELISGSENYKISLVSVVSNNLVIATISGVNSRNEAELLRNKKLYIERNKLPQLNDEDEFYQNDLVNMEVRLESNELYGYVKSVHNFGSGDILEILVISTKKNIMLSFTKEIFPYINMKERYIVINMPEFIGQ
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_COXBU
Sequence: MATAREIPLNRTRNIGIMAHIDAGKTTTTERVLYYTGVSHKMGEVHEGSAVMDWMEQEQERGITITSAATTCYWLGMDQQYPKHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFCSVGGVEPQSETVWRQANRYHVPRLGFVNKMDRAGANFLRVVNQVKDRLNANPIPIQLPIGAEEDFKGVIDLIREKAIYWNEADRGRTYELADIPEDMKAEVQKWREKMIEAAAESSEELMDKYLEAGDLSPEQIRQGLRQRTLANEIVPILCGSAFKNKGVQALLDAVIDYLPSPTDVPAIRGEEDDGSEGSRSASDDEPFAALAFKIASDPFVGTLTFFRVYSGILKSGDSVYNPIKGKKERIGRLLQMHSNSREEIKEVRAGDIAAAVGLKTVTTGDTICNQQNIITLEKMDFPEPVISVAIEPKTKADQEKMGVALGKLAQEDPSFRVHTDEESAQTIIEGMGELHLEIIVDRMRREFNVEANVGKPRVAYRETIRRSVEQQGKYIRQTGGRGQYGDVWLRIEPREPGAGFEFENAIVGGVVPREYIPAVEKGVREQMENGIRAGYPVVDVKVTIFEGSYHDVDSSEMAFKIAGSMAFKEGASKADPVLLEPIMKVEVVTPEEYMGDVVGDLNRRRGMIQGMDESPAGKIVDVEVPLAEMFGYATDLRSLSQGRATYTMEFLKYAEAPSNIAEAIIKQQS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CHLAD
Sequence: MSRSRGMGRPRSRRRECEFTKLGIVPDYKDVKRLQKYLTAQGKILPRRRTGVSAKMQRRLAVAIKRARHLALLPIAPAHTR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FOXN2_HUMAN
Sequence: MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAVDAARPKATLVDSESADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLIQALKKQPFSSASSQNGSLSPHYLSSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFHHPSAVRLQESDSLATSIDPKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIPKNSHVGSDGSEGFHSEEDTDVDYEDDPLGDSGYASQPCAKISEKGQSGKKMRKQTCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKTQNQKQRKK
What is the function of this protein?
Binds to the purine-rich region in HTLV-I LTR.
What are the official names of this protein?
Forkhead box protein N2, Human T-cell leukemia virus enhancer factor.