PharMolix/UniProtQA huggingface dataset:
Protein: DRD1_PIG
Sequence: MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
D(1A) dopamine receptor, Dopamine D1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.
Protein: NRDI_PECCP
Sequence: MNPLVYFSSQSENTHRFISRVGLPALRIPIATEQPALKVDRPYILVVPSYGGGSTKGAVPRQVIIFLNDPHNRAYLRGVIAAGNTNFGAAYCIAGDIIAQKCQVPYLYRFELLGTAEDVANVRKGVTEFWQQQTT
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: STS1_PICGU
Sequence: MATGYNWVPEKYLESKSKHKYGDILQKSDSFKHDLGNSFRKRRHDDDYGKVGKPQSQPTRPIQRSKRIKTPKIIGQALPVSRVVEVLDHRSLQQLLTKLLTIHPEVATTINKLSPRPELKDCLETLRERFDEIINHLPYKCDVESDYSYLRVKPHLNEFLSCLSDLTLSFLPPIEVNTLQSLTFLDYVTSLIHQLPNFANTEFQYTKVQAYDQLANTWIIAFNHSLNDEDCQEVASTKDAKVESLSKIVKMIEDNDLINKLEKHNDLSQGKFRMVIELVKATVDNYESLSESLRAKSLLGDMFTVDYSNFVAAQSLN
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YCXG_PORPU
Sequence: MLIGQKVRIKYSKSKIANDIAVRVGDIGVIRGIKFINNQCVTIIVEFENHTRLWMFREELIYLNK
What are the official names of this protein?
Uncharacterized protein ORF65.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXFAB_COTJA
Sequence: MRTLALSLGLALLCLLHAKAAATVPDRSEIAGKWYVVALASNTEFFLREKDKMKMAMARISFLGEDELKVSYAVPKPNGCRKWETTFKKTSDDGEVYYSEEAKKKVEVLDTDYKSYAVIYATRVKDGRTLHMMRLYSRSPEVSPAATAIFRKLAGERNYTDEMVAMLPRQEECTVDEV
What is the function of this protein?
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid.  May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor.
What are the official names of this protein?
Extracellular fatty acid-binding protein, Ex-FABP, Lipocalin Q83.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MGSA_BACP2
Sequence: MNIALIAHDKKKSDMIQFAIAYRDILADHTLYATGTTGLRVKEATGLPIHRFQSGPLGGDQQIGALIADNAMDLVLFFRDPLTAQPHEPDVSALIRLCDVYTIPLATNMGTAEILVRNLNKGTFDFRDVAKNGGTNETT
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RS4_DELAS
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSIADKSKFDTKPGQHGRTSGQRTSDFGLQLREKQKVKRMYGVLEKQFRRYFEAADKKKGNTGANLLSLLESRLDNVVYRMGFGSTRSEARQLVSHKAITVNGQSVNIPSYMVKVGDVVAVREKSKKQARIVEALQLAGQVGFPAWVEVSADKAEGTFKKSPDRDEFGADINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RIMP_NEIG2
Sequence: MYIGSSMDIQTILEKTLPGLGYELVDFELAAQGTLRVFIDKEGGITVEDCATVSNHLSRVFMVEDIGYKNLEISSPGLDRPLKKAADFVRFAGQNAKIKTRLPIGGQKNFIGKIEGCENDTVTVSFDGKTVQIELGNIDKARLRPEFKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SINMW
Sequence: MPDLLIELRSEEIPARMQRKAAGDLKKLVTDALVEAGLTYEGAREYWTPRRLTLDIRGLNARSADMREERKGPRIDANDKAIEGFLRAAGLSSISEAHVHNDPKKGDFYVAHIVRRGREAEEIVADVMPAIIRDFPWPKSMRSGAASAIPGSLRWVRPLQSIVCTFGAEHDETKVIPFEVDGIVASNITYGHRFHAPEAIAVRRFADYAEKLGKAKVVIDAERRKEIISADAHNIAFANGLELVEDEGLLEEVAGLVEWPKVLMGSFEESYLAIPSEIIRLTIKTNQKCFVTRKPGAETLSNRFILVSNIEAKDGGKEIVHGNGKVVRARLSDAAHFWKRDQGDLPDLETLAASAGKFGLDLKKPLDQRMAKLDALNVTFHAKLGTQGERVARIRSLAAALAKITGADPASVARAAVLAKADLRTEAVGEFPELQGIMGHKYAVLQGESAAVANAIEDHYKPQGPSDHVPTDPVSVSVALADKLDTLVGFWAIDERPTGSKDPYALRRAALGVIRLILEGRARLPLLPCFDVALASLKLQRPAMAADVSGDLLAFFHDRLKVYLRDLGARHDLIDAVLAPDADDLLMIARRVEALTAFITAEEGRNLLAGTKRATQILAAEEKKGTEVAASVDEELFRLDAERLLYASIKVASDGARAAIAKEDFRSAMEALSKLREPVDAFFNDVLVNDEDKAIRANRLALLGLIRSATGEVADFSKISG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_COLP3
Sequence: MTIILGIDPGSRFTGYGVIKQEKQRFTYLGSGCIKAMSQGEDLASRLQTIFAGVSELIIQFKPDMFAIEQVFMGVNPGGALKLGQARGAAIVAATNSGLTIAEYSARQIKQAVVGTGAADKNQVQHMVKSILKLPGTPQADAADALAVALCHGHSHTSAAILAGQATKIVRGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: METN_STRPM
Sequence: MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MIAA_POLSJ
Sequence: MNEVKSVGAKYIALTGPTASGKTAAAMAIAQQHDVEIISVDSALVYRGMDIGTAKPTVDELAAVPHHLINIRDPLQAYSAAEFVADAQRLIDDIAARGKLPLLVGGTMLYFKALFYGLDDMPKADPAVRAELASEAAAKGWPALHAELATVDPVTAARLAPHDSQRISRALEVFRVSGQPLSFFHQQNAAKTIADDGREERTEILISLEPQERSWLHHRIAERFDAMLAAGFVEEVKTLRARGDLTPDLPSMRCVGYRQAWELLDAQEARSPGGSFPMDELRDKGIIATRQLAKRQVTWLRSMPQRQIITCDTDQALPLVLQAVAQHIEKSSR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL7_LEUCK
Sequence: MAFDKDAIIASLKDATILDLADLVSAIEEEFNVSAAAPVAAAGGADGAAAAKTDFDVELTSAGTAKVKVIKAVREATGLGLKEAKDLVDNAPSIVKEGLDEAAANDLKAALEETGASVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GLO2_SHEHH
Sequence: MLQITPLPAFNDNYIWVFQSQQSSGVYVVDPGDGQVVTDYLTQTNLPLLGILITHHHHDHTGGIEQLLKLFGEDTPVYGPQVENIAGVNRPISTNGNITLENIGLNTTVIQVPGHTSGHICYLIEDALFCGDTLFSGGCGRLFEGTAEQMYQSLTQLSLLPDNTRVFCAHEYTLANLHFAKAVEANNPALIEYTVKAHALRAENKPTLPSSIALEKAINPFLRLDSLEIQKSLAVQFQQPIADPVQSFALLRQWKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GLO2_SHEB5
Sequence: MLTITAIKAFNDNYIWVLQQQPHTQVYVVDPGDASVVIDYLEANQLTLAGILLTHHHNDHTGGVAELQAYSQNRLTVYGPDNEKIEGITHPLNATAQPRFILDYMSGELQVLDVPGHTAGHIAYVIADALFCGDTLFSAGCGRLFEGTPAQMLNSLQQLAQLPADTRVYCAHEYTLSNLKFALAVNPNNRALQDYNERAVALRRQDKATIPSTIALERAINPFLRASDTEIVDSIKQHFSDLNHANLDELGGFTLLRQWKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: H2A5_ARATH
Sequence: MESSQATTKPTRGAGGRKGGDRKKSVSKSVKAGLQFPVGRIARYLKKGRYALRYGSGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRINPRHLCLAIRNDEELGRLLHGVTIASGGVLPNINPVLLPKKSTASSSQAEKASATKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.5, HTA7.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RRP36_ASPFC
Sequence: MAVSDLLNRRVRALPDEDEELYSEASVSELESNDEEVEGSGSDISDDSSEGDYSSDSQDESDAMSHENEEEDDEDDENSDDGQDDVQASLSNISFGALAKAQASLGPTAKRKSKATQSKTDDGETPAASPLDDIRARIREAREQKREGSSKSKDLEKFSRSSKHAPMVQSSKHPVTRKRTIIEPPAALKSRDPRFDPAVRSQSGRSEASQSAYAFLDDYRAAELKEMKEKLAKTKDPRQKEALKRDIRSATDRLRTIENRRREKEVLAEHKKREKELIREGKKSTPYFLKKSELKKQALLKKYESMGSRQRVKALERRQKKLTAKERKEMPMERRGLGNDPTPYNDGGGGKRRRLA
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MATR3_HUMAN
Sequence: MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET
What is the function of this protein?
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.  In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.  Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728).  Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs (PubMed:32245947).  May bind to specific miRNA hairpins (PubMed:28431233).
What are the official names of this protein?
Matrin-3.
Protein: MODC_BORPA
Sequence: MPSDFPPGQAGIHARFRVDYPEFSLDVDLRLPGRGVTALFGQSGSGKTTCLRCMAGLAPVSDGYLDINGEVWLDSAARRAVPTHKRALGYVFQEASLFEHLDVLANLRYGMKRVPPALRRVDLEQATGLLGIGHLLARMPAGLSGGERQRVGIARALLTSPRLLLMDEPLAALDVQRKREILPYLERLHDELDIPVIYVSHSPDEVARLADHLVLLEQGRAVASGPLDALLTRLDLPMAMTDDASVVVTGEAAGFDPGYALLTLQLPGGRARLRFVHQAAPAGQRLRVVVHARDVSLALQQPREGSILNVLAVRVLEMAPAANPAHVMVRLDADGTPLLARITRYSRDRLALAPGMQAWAQIKAVSLLA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL15_EDWI9
Sequence: MRLNTLSPAEGSKHASKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAMVTAEIRLSEIALIEGDVIDLNVLKAANVIGPQIEFAKVMLSGEINRAVTLRGLRVSKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RIMM_MYCTU
Sequence: MELVVGRVVKSHGVTGEVVVEIRTDDPADRFAPGTRLRAKGPFDGGAEGSAVSYVIESVRQHGGRLLVRLAGVADRDAADALRGSLFVIDADDLPPIDEPDTYYDHQLVGLMVQTATGEGVGVVTEVVHTAAGELLAVKRDSDEVLVPFVRAIVTSVSLDDGIVEIDPPHGLLNLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM216_HUMAN
Sequence: MLPRGLKMAPRGKRLSSTPLEILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAMMASYYLLLQTYVLRLEAIMNGILLFFCGSELLLEVLTLAAFSRI
What is the function of this protein?
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
What are the official names of this protein?
Transmembrane protein 216.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: APEB_PSEU2
Sequence: MRAELNKGLIDFLKASPTPFHATATLVQHFEAAGFQRLDERDTWAVETGGRYFVTRNDSSIVAFRMGRQSPLSGGIRMVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRDGKVESQLIDFKLPIAVIPNLAIHLNRTANEGWAINAQNELPPILAQVAGDERADFRALLTDQLAREHGLNADVVLDYELSFYDTQGAAVVGLNGDFLAGARLDNLLSCFAGMQALLNTESDETALLVCTDHEEVGSSSACGADGAMLEQIVQRLLPSSEDYVRTIQKSLLISADNAHGIHPNYADKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGSTIGPITASHLGIRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLSAFYASHELP
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: SECB_RHOP5
Sequence: MTNGNGTPPEAAPPPQLNVLAQYTKDLSFENPNAPASLAPQPQQPAINIQINVGAKALAENEYEVTLSIEGKAEGASSLIFSFELQYAGVFRIVNVPQENLHPLVMIECPRLLFPFAREIIATAVRDGGFPPLMLDPVDFVGLYRQNMDRQAAEAQQASPN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYNJ1_HUMAN
Sequence: MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPTLDFTER
What is the function of this protein?
Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:27435091).  Has a role in clathrin-mediated endocytosis (By similarity).  Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (By similarity).
What are the official names of this protein?
Synaptojanin-1, Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1.
What is the protein family that this protein belongs to?
In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: CSN1_SCHPO
Sequence: MSLNLLVNQEELKRYLDEYGVWSKIFRALFVARNSKPLRSFCVHYAIKELKEKTYNLELYQSLFEEFQDCFENEQLDVEWVESVTFHRKQNLEQLRRELKAYKNNLIRESIRAAQLDLASFFADVGQFDSALRSYAKVREYCTNAGQIAHLSLELMRISIWIGNYSHVLAFGSRAKSTVSAAMELTSPIYAYCGLANFCLGDYEEALAHFLKVETDTSDGIITKTDISVYISLCALACWDHKRLIQELERNEEFNALSDLDPSLRRCLQAKCNRKYSLLLDTLQQNAQDYSLDMYLAPQLTNLFSLIRERSLLDYLIPYSALPFSKIAVDFHIDENFIEKNLLEIIEAKKLNGKVDSLQKRVYIEPSSEPENFEDIKNIAQTSLLYSKALYLQTLAAMNTENTDDEAPVIAQTNITAEDSQN
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  Required, indirectly, for activation of ribonucleotide reductase through the degradation of the protein spd1, thereby supplying deoxyribonucleotides for DNA replication and repair.
What are the official names of this protein?
COP9 signalosome complex subunit 1, CSN complex subunit 1, SGN1.
What is the protein family that this protein belongs to?
Belongs to the CSN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURL_LISIN
Sequence: MPNMEPTTKEIKEQKIYQEMGLTDSEYELVCSILGREPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTEGKQVLQGPGEGAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFGELDTPHAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCVGLIEAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFASVEFSEEGEQQRSAVQVGDPFMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELHMTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGKVTDDKMYKIIHHGEVVANVPVDALAEDAPVYHKPSKEPARYQAFQEEDAFVPVIDDVVGVWKELLAQPTIASKRHIYEQYDYQVRTDTAVVPGSDAAIVRVRGTEKAIAMTTDCNSRYLYLDPEVGGAIAVAEAARNIVCSGGKPLAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVISGNVSLYNETDGTGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEYSGSELQKLQQGKISGRAPELDLATEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALAEATFKAGLGADVEVPFELNQLFSESQSRFLVSVKPENEAAFAKLMELEKVYRLGVVTADETIRVKHKEELVTASTSDLRSIWEGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHB2_STRCO
Sequence: MHHTLIVARMAPGAAPDIAKVFAESDSGELPHLVGVNRRSLFEFGDGVYLHLIESDEDPAPTIGRLTGHPEFRQVSERLEPYVSAYDPATWRGPKDAMARCFYRWERTPAG
What are the official names of this protein?
Uncharacterized protein SCO5314, WhiE ORF VII.