PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_PSEPF
Sequence: MSEFQLVTRFDPAGDQPEAIRLMVEGIEAGLSHQTLLGVTGSGKTFSIANVIAQVQRPTLVLAPNKTLAAQLYGEFKSFFPNNAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDHIEQMRLSATKALLERKDAIIVTTVSCIYGLGSPETYLKMVLHVDRGDKLDQRALVRRLADLQYTRNDMDFARATFRVRGDVIDIYPAESDLEAIRIELFDDEVESISAFDPLTGEVIRKLPRFTFYPKSHYVTPRETLLDAIEGIKVELQERLEYLRNNNKLVEAQRLEQRTRFDLEMILELGYCNGIENYSRYLSGRPAGAAPPTLYDYLPADALLVIDESHVSVPQVGAMYKGDRSRKETLVEYGFRLPSALDNRPMRFDEWEGVSPQTIFVSATPGNYEAEHAGRVIEQVVRPTGLVDPQVEVRPALTQVDDLLSEITKRVAVEERVLVTTLTKRMAEDLTDYLADHGVRVRYLHSDIDTVERVEIIRDLRLGTFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGRAILYADRITGSMERAIGETERRRDKQIAFNLANGITPKGVFKDVADIMEGATVPGSRSKKRKGMAKAAEENAKYEAELRSPSEITKRIRQLEEKMYQLARDLEFEAAAQMRDEIAKLRERLLAV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB24_ORYSJ
Sequence: MAGEGVEMSEEEGAFEAFVCPLTKQVMRDPVTIETGQTFEREAILKWFRECRDNGRRPTCPLTQRELRDTEVSPSVALRSVIHEWRARNEEKDLDRACASLVGGFAGHAGDEEEEESALRALVHVSQICQRSAASKDLVRRRGVLRAVAEMLKSGSRRLRLKSLQVLRVLVEDNDDNKEELGKGDTIRTIIKFLSNEHVQERELAVSLLHELSGHEPTCERIGAVYGAILLLVGMGSSKSESAVAVDKAESTLRNLDRFDANVKQMADNGRLQPLLTRLLRGEPDTRVAMADYLGELALANDDKAAVAEQAGPLLVGMLRTGATPAKEATLKALREISSSEASAKLLLQRAGVLPPLVNDVLFSTGHLPMKLKELAATILANLVASGADFRSIPLDDDEDDDGGGGGRGRRRTLLSEDVVHSQLHLISNTGPAIGCRLLSVLAGLTSSRATVADVVAAVKSSGATISLIQFIEAAHRDIRVESLKLLRNLAPYMGAELADALGGSLSSLLRAISSDGGGVTEEQAAAVGLLGDLPEGDSSLTRQLFDLGAFRALAPKLAELRRGTIRGGNRYVTPLTEGVVKVMYRVTCALEEDAEYVEFAREAGLAPLFVELLHTNGMDTVQLYSAMALEKLSLQSSHLTAIPAPPSPPAGFGCACLGRRPAAAAVPAGVCRVHGGFCSLRETFCLAQADGGKAVERLVACLDHLDGRVVEAALAALSTLVCDGVDAREGVVVLGEADGLRPVVDIMVESRTEALQRRAVWAVERILRVEEIAGEVAADQTVASALVEAYRNGDPRTRQTAERALRHLDRIPNFSAAFQSKRS
What is the function of this protein?
E3 ubiquitin-protein ligase that functions as a negative regulator of brassinosteroid (BR) signaling (PubMed:30920691).  Targets BZR1, a positive regulator of BR signaling pathway, and promotes its degradation via the ubiquitin-26S proteasome pathway (PubMed:30920691).
What are the official names of this protein?
U-box domain-containing protein 24, Plant U-box protein 24, OsPUB24, RING-type E3 ubiquitin transferase PUB24.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RSMF_SHEON
Sequence: MVQLNPNFINTISQELPAHLSMDEFIAACARPLRRSIRVNTLKISSEDFKRLMQPKGWTFEPIPWCKDGFWISYDEEEQLGNALEHIQGLFYIQEASSMLPPTALFTPNADWQCVLDLAAAPGSKTTQMAALMNNQGLLVANEYSASRVKVLHANVLRMGASHCALTHFDGRVFGEYLYESFDAVLIDAPCGGEGTVRKDVDALKSWSLDEVIAISETQKALIESAFLALKPGGSLVYSTCTLNRHENQGVCEYLQQTYGNAVQFESLSQLFDGADKATTPEGFLHVWPQIYDSEGFFVAKLTKTRSVPRLQLEPKLQKNFPFTEASPKQAKAIQAYFADDLGIELPDELIMVRDDEFWLFPREFTDFIGKMRFQRIGLKLADHSKHGFKVRHEAVIALANTQANIIEINDEQAKEYLMGRDIALDTATKAQGEIIVCYGGAPLGMAKHLGNKLKNNLPRDLVKDKVLLLPSQA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_FRATM
Sequence: MGSYMNKTSVVKVGNVLIGGDNPVVVQSMTDTYTADVEKTVRQILALHKAGSEIVRITVNDESAAAAVPEIVKELAKHDCHVPLVGDFHYNGHTLLSKYPECAKALAKYRINPGNVGFGKKKDTQFAEIIKIAIANDKPVRIGVNWGSLDQALLARLIDENNAQENPLSLQQIMYKALITSALESAKYAEELGLAKDKIIISCKVSEVQDLIAVYQKLAKECDYALHLGLTEAGMGTKGIVASAVSLGILLQQGIGNTIRVSLTPAPNAPRTEEVRVCREILQNLGMRTFTPSVTSCPGCGRTTSSFFRELTSKVKDHLDEKMHTWKEQYHGVEAMKVAVMGCVVNGPGESKNADIGISLPGSGESPVAPVFIDGKKAHTLRGDNISEEFIEIVENYVKNRYGKK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TIG_PROMT
Sequence: MSAAKLNVKTSAKPNSRIAVEVEVPANRCKNSYDEALSKLSRSISIPGFRKGKVPKTVVIQQLGVKRIQASALESLLQKVWTETLDQEGIEPLCEPELEDGFETILENFNPEKTLILKLETDITPIPTLKKSSGLTAEVENLIFDPKKVDELIEQSRAQLATKVPVSDRAAQKGDIALVSFKGSFSDDGSEIEGGSADSIEIELEQGRMIPGFIEGVIGMNINDEKTLKCEFPKDYHQEEAKGRKAEFNVSLEDLKIKELPELNDEFAKQASDKENMSDLRADLEKRLKEDNDRKQAKTRQDSLLDVLVKELEVDLPKSLIDQEVRTIVEQTAQNFAQQGIDVKSMFTPELVKSLMESSKGEAEKKLRQKFALQALAKSEKIEVSDKEINSKLEQVEADIKLSNEKNIDAERLKEAITDDLLQEKLFAWLEENNTVVEKTPEKARDQIKEKSSKKKTTKTNKEKKSSKTPKS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GH109_TANFO
Sequence: MENTRRNFLKKVTAAGIGAAGLAVTDQAMAAVNQPGEAAQQKKKPAGKSDGMLRFGFIGTGSRCQEHINNVLGIQGNKIVAICDIQKGPLEKTLKHIAKFNVPEPKVYTGGEREFEKMLNNEEFDCVIIASPWEWHVPMAVAAMKAGVPYVGVEVSAANTVEECWDLVNVSEATGSHLNILENVCYRRDVMAALRMVREGLFGEMIHGTCGYQHDLRDVKFNDGIHYTYQEGGELRMGPTAYAEAQWRTQHSVTRNGDIYPTHGIGPVANCLNINRGNRFLSLTSMATQSRGLHNFVVDKGGANHPYAKIHFNLGDIVTSMIKCANGQTVIVTHDTNLPRPYSLGFRIQGTRGLWMNDGNHVYVEGQSKPHRWDASDDWFKKYDHKLWSTLELKAKEAGHGGMDYIMMYDFIDAIRNKKPTPMDCYDAAAWSAISGLSEMSIARGGAVVDFPDFTRGQWIHRQPAFAL
What is the function of this protein?
Glycosidase that has specific alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: PTC71_DROVI
Sequence: MFFTVRTLSNRTSHVLNCAFAQCRLLSSTASAKGVPRLIKAIQGSSKEPLTDLQLRLIGDNRYGEDSWFVSSTPKAETMGVADGVGGWRKLGIDAGVFARELMSHCSEFAEQAEYDGLNPRQLLIDSYDRLKNKRPCNVCGSSTACLVTLHRPDCTLHSANLGDSGFLVLRNGRVLHRSDEQLHCFNTPYQLTVPPHPAMDCVLRDSPEQAVSTHLPLQPGDLVLLATDGLFDNVPESMLINQLRALQGETRAEYLQQAANRLVDLAKTLSVSPTFQSPFALKARANNVDYGIGGKPDDITVILASLEVPDKL
What are the official names of this protein?
Protein phosphatase PTC7 homolog fig, Fos intronic gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RS3A_AJECH
Sequence: MAVGKNKRLSKGKKGLKKRTQDPFSRKDEYSVKAPSTFAVRDVGKTLVNRTTGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTSDKLRSLVRKWQTLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKITEIIQREASTRTLAQLTKLIPEVIGREIDKSTHGIYPLQNVHIRKVKLLKSPKFDLGALLALHGESSTDDKGQKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLE_ARALL
Sequence: MVKLTQRLGGLVLRFAAFCAALGAVIAMITSRERSSFFVISLVAKYSDLAAFKYFVIANAIVTVYSFLVLFLPKESLLWKFVVVLDLMVTMLLTSSLSAAVAVAQVGKRGNANAGWLPICGQVPRFCDQITGALIAGLVALVLYVFLLIFSIHHVVDPFLLRKS
What are the official names of this protein?
CASP-like protein 1C2, AlCASPL1C2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_VIBC3
Sequence: MQGSVTEFLKPRLVDIEQISTTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIEGVLHEYSTKEGVQEDILEILLNLKGLAVRVAEGKDEVFITLNKSGSGPVVAGDITHDGDVEIVNPEHVICHLTSDNAAIAMRIKVERGRGYVPASARIHTEEDERPIGRLLVDATFSPVDKIAYSVEAARVEQRTDLDKLVIDMETNGTLEPEEAIRRAATILAEQLDAFVDLRDVRVPEEKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL33_CITK8
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KRA3A_SHEEP
Sequence: TGSCCGPTFSSLSCGGGCLQPCCYRDPCCCRPVSSTQTVSRPVTFVSRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPTSCQAVVCRPCCWATTCCQPVSVQCPCCRPTSCPSAPRTTCRTFRTSPCC
What is the function of this protein?
The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins.  The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).
What are the official names of this protein?
Keratin, high-sulfur matrix protein, IIIA3A.
Protein: SYK_RHIL3
Sequence: MADNKSENTLSSDATEVRAQKLKLLREQIGEVYPAHFHRTMTNAELIAKYENLEPDVETQDVVTVAGRVYSSRNSGMFMDIHDARGKIQIFSHKDTTPEEARALLPMIDIGDIIGVTGSVRRTKRGELTINAQTITMLTKSLLPMPEKWHGLSDIELRYRKRHLDIMTNEDSKLRFQQRSKILSGIRRFMENDGFMEVETPMLQSVYGGATAEPFKTHHNTLKLDMYLRIAPELFLKRTLISGLTDKVFEVNRNFRNEGVSTRHNPEFTMMECYWAYADYEDIMDLVERLFESLALSIHGTTEFPFGDKTMSFKGPFKRVPMPDAVKEATGIDFRAIKTDEEARVAAKAAGFAVEKDWTWGECLAFIFEEKVESTLIQPSHVTHFPKDISPFAKEVPGEPRLVERFETYCNAWELGNAFSELNDPEEQRRRMVEQLEQAHARGEKEKQLDEEFLDAIDQGMPPAGGLGIGVDRLIMLLTNAPSIRDVILFPARRSKAD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBI4P_SCHPO
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGLF
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS8_MANSM
Sequence: MSMQDPIADMLTRIRNGQAASKVAISMPSSKLKVAIANVLAAEGYIESVKVLEGAKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RUBR3_RHOER
Sequence: MSSYRCPVCEYVYDESKGAPREGFPAGTPWDAVPDDWCCPDCGVREKLDFEPMPATAGSES
What is the function of this protein?
Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
What are the official names of this protein?
Rubredoxin 3.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: HEM1_CUTAK
Sequence: MTVDHAEQGLGVVSEAAAQVDGLGLALTDHPQIRGALVLSTCNRVCLIVETSPEAVAQGFDEAALRRCIADHGANVLAESAQLVCENDAVWRLFRVAAGMESMVFGEREVAGQMKRALSEARREQTVSYTIGHVVEEALKTSRHVATETALAAEGRTVVAVGLDLVAQRMDLDGARVLVMGTGSYAGASCAQLSSRGVAEIQVHSASGRAAGFARRHRVSEALDIDAALAQADLVVTCRGSGVPALSAEAARRAVDARRGRDLMVLDLAISGDVEEPVPAGVEVIDLETIRQAVPASAEAERAAAEHIIATGVRHFAVDLERRRMAPAVVALRDVISDLVTAELERLPEEGSVPVDEVAASLRRLAASMAHIPSARARMASEQGLGDRWLNSLSDVLGIDVDIAAPVIDMSSFANADCMTCPVTGLRVEDLATDAAPRGEERTS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ENGB_PETMO
Sequence: MKVYKAQLIKTVYKIEDLPPPDKKEIAFAGRSNVGKSSFLNAILGIKIAKVSSTPGKTRSINYYLVNDKYYFVDLPGYGFASVSKQEKERWNVLMNEYFKTRFSLSAVSLLIDHRHMPQKLDYAMVEWLKDLGTPFLFILTKSDKLTKSEKAKLFEDIKRSFSTYGEYIYMPFSSKTKEGLKEVLKTIGEILGDND
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CDPAS_AERPE
Sequence: MALELAVDWRIDNILEAIILMLPAMIANATPVVAGGRRPVDMGVVLPDGRRLLGDGKTIEGLLAGFAAGSAAGVLAALASGNMLLAVHSPAIALGALAGDMAGSFVKRRLGIERGRPAPLLDQLDFYLGALAVSIALGYTWTPRVAVEAAAAVLLLHLAANITAYLLGLKKVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSIR_PSICY
Sequence: MAPTTPATHDPALSHGAPPTQGSQAPANAAPNLTPADISGMQLNGLDQSQIMNLLRSLPGMFTGAKIPDQGQGNPKEDAAQTLSNLAQASSPFGGQHLPIHYQTGAAGGLPGINDPGPSTHPRGPPNLGQLSAVAMQAAPATIQHQDQQQSGRQEDGEQAGNTSIDSPSAKDGENGTGEFNQTSTSTPSGGRRGGRSATMGSDEWSRQRKDNHKEVERRRRGNINEGINELGRIVPSGSGEKAKGAILSRAVQYIHHLKENEARNIEKWTLEKLLMDQAMGDLQAQLEEIKRLWEEERMARTRLEAELEVLRNMNGVSTAGAGSGAAKDESAAGTKRRSTDGADAAGTNVEGGNNDNAEGERDGKRQRTE
What is the function of this protein?
Transcription factor that may regulate the expression of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product.
What are the official names of this protein?
Psilocybin cluster transcription regulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: LHB1_RUBGI
Sequence: MAERKGSISGLTDDEAQEFHKFWVQGFVGFTAVAVVAHFLVWVWRPWL
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-870 beta chain, Antenna pigment protein beta chain, Light-harvesting protein B-875 beta chain.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SAMBA_ARATH
Sequence: MNGASPAHSLVSTTAVAGGGGSSGAAAGLDDFHFPPDIPSMQERKDEAMRVLKADLMTELDKEVKSLEEDSWMFEGPRSRIHLISRRGNFLKKGGEVKLW
What is the function of this protein?
Plays an important role in organ size control.  Acts as negative regulator of the anaphase-promoting complex/cyclosome (APC/C).  Regulates cell proliferation during early development by targeting CYCA2-3 for APC/C-mediated degradation.  Required for mitosis I during pollen microspore development.
What are the official names of this protein?
Protein SAMBA.
Protein: OBG_RHORT
Sequence: MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFRYQQHFKAARGRDGSGDNRTGKSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKGGDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIADAGLIGLPNAGKSTLLAAVTRARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVLLHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEACGAPVMAFSAISGKGLADVLRVMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNRPSAVVDWEDAPFDDDDDDDGDESGDKGQWTR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_MYCMM
Sequence: MDPTIAAGALIGGGLIMAGGAIGAGIGDGIAGNALISGVARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPVK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS2_CLOB1
Sequence: MNRNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEELIKEICDLTYHIMVLMVEKQIKLDDIEKELEKRRERICNKKNERKTIEKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHR_PIG
Sequence: MPVLGPERRLLASLSSAPPAAPRLGLAANQTNQTGPQCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYYFVCCLAVSDLLVSVSNVLETAVLLLLEAGALAAQAAVVQQLDNVMDVLICGSMVSSLCFLGAIAVDRYVSIFYALRYHSIVTLPRAGRAIAAIWAGSVLSSTLFIAYYHHTAVLLGLVSFFVAMLALMAVLYVHMLARACQHGRHIARLHKTQHPTRQGCGLKGAATLTILLGVFLLCWAPFFLHLSLVVLCPQHPTCGCVFKNVNLFLALVICNSIVDPLIYAFRSQELRKTLQEVLQCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH (By similarity).  The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (PubMed:9799269).
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LGT_YERPG
Sequence: MSNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKEEVENLLYAGFLGVFIGGRVGYVLFYNLPMFLDNPLYLFKVWDGGMSFHGGLIGVICVMLWFARRTKRNFFQVADFIAPLIPFGLGAGRLGNFINAELWGRVTTDTPWAMLFPTSRNTDIAIVAADPAKWQAIFNQYGVLPRHPSQLYEMILEGVVLFIILNVFIRKPRPMGSVSGLFLIGYGTFRIIVECFRQPDEQLGLFEGMISMGQILSVPMILAGIIMMIWAYRRPTQKLS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HGLS_SHIFL
Sequence: MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVLENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQAGVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCRQLLEEYEQQGGFNETQAQEFVQEALETFRWHQLATVDEETYRALHNEHRLIADVVCFPGCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLFAGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFPDSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVSAAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL
What is the function of this protein?
Catalyzes the decarboxylation and hydroxylation of 2-oxoadipate (2OA) to form D-2-hydroxyglutarate (D-2-HGA).
What are the official names of this protein?
2-oxoadipate dioxygenase/decarboxylase, 2-hydroxyglutarate synthase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.
Protein: G1PDH_GEOSE
Sequence: MNQTLEEVVSLARQCGCGHRHYDIPIEQMVVGREAFARLVAYLRHKRYERVAIVADDHTFAAVERSLCDQLENGSIRYTVCLVQPDENGDVIADERSIVQVLLETPDDVDVLIAVGAGTIHDITRFSSYKMRIPFISVPTAPSVDGFTSMGAPLIIRGVKKTIQAQAPIAVFAHTGVLCQSPKEMIAAGFGDMVAKYTSLADWQFAHWMADEPYCPFVHQLTEQSLQTCVDHIDDIAAGGEQGIRVLMDALLQSGIAMLLMGQSYSASGAEHHLSHYWEMEFLRQKKRQVLHGAKVGVSTPIIIEHYQRVFWPLLNELEKRPKSMDEATWERLKANTASIRELLESLPSPERIRTMLAKVGGAIAPEQLGIDPQLVERSLREAHRLRLNRFTMLYFLNELIFVE
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.