PharMolix/UniProtQA huggingface dataset:
Protein: GCP3_DROME
Sequence: MSQDRIAGIDVATNSTDISNIINEMIICIKGKQMPEVHEKAMDHLSKMIAANSRVIRDSNMLTERECVQKIMKLLSARNKKEEGKTVSDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQCDNLTQILVSRLNSISSSIASLNEMGVVNGNGVGAAAVTGAAAVTGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLSELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSYTPDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSALRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAMLESTMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLNSSDDPNLQLFGTRLDFNEYYKKRDTNLSKPLTFEHMRMSNVFAVNSRFVICTPSTQE
What are the official names of this protein?
Gamma-tubulin complex component 3, Gamma-ring complex protein 91 kDa.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: TUSB_ECOBW
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_ECO57
Sequence: MSFNTIIDWNSCTAKQQRQLLMRPAISASESITRTVNDILDSVKARGDDALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDADMAHQVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKVGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: RS15_STRPG
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIKEHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GP119_MOUSE
Sequence: MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
What is the function of this protein?
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC).  Functions as a glucose-dependent insulinotropic receptor.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Seems to act through a G(s) mediated pathway.
What are the official names of this protein?
Glucose-dependent insulinotropic receptor, G-protein coupled receptor 119.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_GEOUR
Sequence: MAGMRIIFMGTPEFACPTLQKLLDRGEDVIAVITQPDRPKGRGQQTLPPPVKVLAERHGIPVMQPLKVRVPEVVESIRSLAPDLIVVVAFGQILPKSLLDIPKYGCINVHASLLPRWRGAAPLNWCIINGETETGVTTMMMDVGLDTGDMLVKRSTPIDPDENTQSLHDRLSVVGAEALAETLDLLTAGKLVREKQDDALTCYAPMLKKEDGLIDWSKEPQTIKNLVRGMTPWPGAFSFLDGKMLKIYRVGTAGGEGTPGSVIRAGREGLEVACSGGSIVIEELQLEGKKRLHAGDFLAGYKIAPGSILGKKD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RS27A_THEKO
Sequence: MAKGKKKTSQKWKLYEVKGGKVVRKNKFCPRCGPGVFMANHKDRWSCGRCGYTEWKK
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: MTNA_THEP1
Sequence: MKLKTKTMEWSGDSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVTAAFGYVLGLRDYKTGSLTDWMKQVKETLARTRPTAVNLFWALNRMEKVFFENVDRENLFEILENEALKMAYEDIEVNKAIGKNGAQLIKDGSTILTHCNAGALATVDYGTALGVIRAAMESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKKGLIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIKSGEEIPIEERRPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLITAIITEKGVIRPPFEENIKKILGV
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: MURE_ACTP2
Sequence: MKRLLPFLTELDAWVTELKPLKQMTLDSRQVDEGDLFVALKGHQVDGRRFIQKAIEQGAALVLAEADEGQDEIELDAKFAKYNLDRTACKVVLVPNLARILSEIAGAFYANPSEKLTLVGVTGTNGKTTSAQLLAQWHNLLGGKSAVMGTIGNGLYGKVQEAANTTGSAIEVQRNLADFVEMGADFCAMEVSSHGLAQYRAEALSYDLAVFTNLSRDHLDYHKTMEEYAQAKFRLFSELDTKAQVLNADDEVGREWLAKLPDAVAVSTDASFSSEHKFVKATDVSFSLQGVKIAFESSWGNGELNSRLIGAFNVNNLLTALAGLLVLGHDLPKLIETAPLLQGVAGRMECVVSQKNPQNRPLVLVDYAHTPDALEKALQAARLHTEGELYCIFGCGGDRDAGKRPMMAAIAEELADKVIATDDNPRTEDNAKIMADILNGFVQVEKVQVIHDREQAIKTAIEQANEKDVILIAGKGHEDYQIIGTTKHHFSDQETAAKYL
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_YERPG
Sequence: MSLSVEAKAKIVADFGRGTNDTGSSEVQVALLTAQINHLQGHFSEHKKDHHSRRGLLRMVSTRRKLLDYLKRQDVARYASLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FOLD_SODGM
Sequence: MVAKIIDGRAVAQQVRSEVAARIQARLKAGKRAPGLAVVLVGGDPASQIYVASKRKACEDVGFISLSYDLPNTVTEAALLALIDQLNADHRVNGILVQLPLPAGIDNISVLERIAPDKDVDGFHPYNVGRLCQRAPLLRPCTPRGIVTLLERYHIDTFGLNAVVVGASNIVGRPMSLELLLAGCTVTVTHRFTRDLRRHIENADLLVVAVGKASFIPGEWIKPGAVVMDVGINRLESGKVVGDVDYASAAERAAYITPVPGGVGPMTVATLIQNTLQACEDYHDTTMPEA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: COAX_BURM1
Sequence: MSEPHLLIDAGNSRIKWALADAQRTLVRTGAFGHTRDGGADPDWADLPRPRGAWISNVAGADVGARLDALLDTRWPGLPRTTIRSRPAQCGVTNGYTTPEQLGSDRWAGLIGARAAFPDEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPTLTTDIASGLLADAQAQPFQVDTPRSLSAGCLYAQAGLIERAWRDLAAAWQAPVRLVLAGGAADEIARALTLPHTRHDALILSGLALIAAEASAQD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAI_AGRFC
Sequence: MRILTVSPDQYERYRSFLKQMHRLRATVFGGRLEWDVSIIAGEERDQYDNFKPSYLLAITDSGRVAGCVRLLPACGPTMLEQTFSQLLEMGSLAAHSGMVESSRFCVDTSLVSRRDASQLHLATLTLFAGIIEWSMASGYTEIVTATDLRFERILKRAGWPMRRLGEPTAIGNTIAIAGRLPADRASFEQVCPPGYYSIPRIDVAAIRSAA
What is the function of this protein?
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to TraR and thus acts in the control of conjugal transfer.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein TraI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: VIRB4_RHIRD
Sequence: MLGASGTTERSGEIYLPYIGHLSDHIVLLEDGSIMSIARIDGVAFELEEIEMRNARCRAFNTLLRNIADDHVSIYAHLVRHADVPSSAPRHFRSVFAASLNEAFEQRVLSGQLLRNDHFLTLIVYPQAALGKVKRRFTKLSGKRENDLAGQIRNMEDLWHVVAGSLKAYGLHRLGIREKQGVLFTEIGEALRLIMTGRFTPVPVVSGSLGASIYTDRVICGKRGLEIRTPKDSYVGSIYSFREYPAKTRPGMLNALLSLDFPLVLTQSFSFLTRPQAHAKLSLKSSQMLSSGDKAVTQIGKLSEAEDALASNEFVMGSHHLSLCVYADDLNSLGDRGARARTRMADAGAVVVQEGIGMEAAYWSQLPGNFKWRTRPGAITSRNFAGFVSFENFPEGASSGHWGTAIARFRTNGGTPFDYIPHEHDVGMTAIFGPIGRGKTTLMMFVLAMLEQSMVDRAGTVVFFDKDRGGELLVRATGGTYLALRRGTPSGLAPLRGLENTAASHDFLREWIVALIESDGRGGISPEENRRLVRGIHRQLSFDPQMRSIAGLREFLLHGPAEGAGARLQRWCRGHALGWAFDGEVDEVKLDPSITGFDMTHLLEYEEVCAPAAAYLLHRIGAMIDGRRFVMSCDEFRAYLLNPKFSAVVDKFLLTVRKNNGMLILATQQPEHVLESPLGASLVAQCMTKIFYPSPTADRSAYIDGLKCTEKEFQAIREDMTVGSRKFLLKRESGSVICEFDLRDMREYVAVLSGRANTVRFAARLREAQEGNSSGWLSEFMARHHEAED
What is the function of this protein?
A possible function of virB4 might be to provide the energy, via hydrolysis of ATP, for translocation of virulence proteins of the transfer of a T-DNA-protein complex across the agrobacterium membrane.
What are the official names of this protein?
Protein virB4.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
Protein: GLGA_PHOPR
Sequence: MATKKTSLTKHPLKILFVSSEVEGFAKTGGLADVAKSLPAALKKMGHDVRIVMPFYQTINGKDNAVAILSTELLVESQPFAVSYQVMQLDEGNVPVYALDAPQYYDRPELYAENNQAYADNGERFTFLSAASLDLCEKLGFQPDVIHCNDWHTGLIPFLLKTRYAESDFFAKSKSVITIHNAVFKGVFNYDQYSLIPELIQRRYINAEMDPSHISMLKAGVAYADKVNAVSPNYASELLTHLGSHGMEADFQNRAKDLYGIINGCDYDDWNPETDVYIKQKFKANKVSLARGKKACRRDLQKQVNLPEVDVPVYGMVCRLTEQKGLHYLIPVLEDFLLNDVQVVIVGTGDPTLASALRDISEQHSDKFAFVETYSNPLAHCVEAGVDFFMMPSEFEPCGLNQMYSLAYGTLPIVRSVGGLKDTVIDYDQTPQVATGFIYDTPTPEALLIKLQRSLLLYCQRPQEFKRLQQNAMACKFNWDESAEQYLDMYLGGEQSLVNEICNDKVDA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ALKS_ALCBS
Sequence: MLCDNLENWCLRMSDRMWARQRFITQGCIERGRLKASAESESKVILYRAPLGYGKSVQVAFEAGTQGREEGGVAYINTRSYPGSGEITDSLLAALILYQIKGREPWSVIQSNDDIIESLRDTLCNAKNPIKICIDGIGEAEHGVGLVENLICETPNNVKFYIAPSNAGALARLSMMAGVVTYGAHDLVFTEEEVCELPGMHSAKAKNVIEATGGWPALVGLMCHTSNPNLPAATWPETRSYFRNNLLNALPNNTREFICKAAMLEEISVACYDYVYKTEEAHKEIPFINENYALFTPTESSRECMVMHPVLREYLRGLFDSIQRERRSYVLKRVAFWHWRRGEYLHSINAAQEASDHSWARAVSDSIILDVALRQGEIEVLRTWFEKVPVRTIKKIASLSISYAWILYFSQQARQAEKILASSTESCSRGLDNLDEKGWRKLVDAVGKATQDQFAQSQTLCQQWIDTFGERNMVGKGAALTCQAYIASSDRRFEDLEQLLHRGAVANQSSNQHYAFVWLKTAELQAEIFKGDIAHAMSILLEANKTAEKMGVSKTFLNKMLGSLELQILHEKSPSLISYESAEESFNFALNYGVTDILWGCTQTFSSFLYQQGLRDRAMAILEQTRIAACERDLPRLNMLAKIQLAEFTLINDEELEPPILPDESELTFLPNQNQAIRARIALVNSMYRLRLGKQFGVAEKYAKKALQSASAISDARTKIAAQYCQALAVFGLGSSKLAKRTIIDADQLTEHLSCYFTRDWIKEALMSFSPIARDLFDTLPESAETNATKDLEVRKEEADARPKLTNTQSTITIKQISLLKCVSSGMTNKEIAERLLITEDTVKWHLKKIFSELKVTNRVRAVSEARLRGLL
What is the function of this protein?
This protein activates the expression of AlkB1 in the presence of alkanes.
What are the official names of this protein?
HTH-type transcriptional regulator AlkS.
Protein: RIMP_VIBA3
Sequence: MTGLERQLTEMLDAPVAASGYELVGLEFIRAGEHSTLRIYIDSPNGINVDDCSEVSHQVSAVMDVEDPISVAYNLEVSSPGLERPLFKAEHYQQFIGHEVSIVLKMAVGNRRKWKGDIQSIEGETVKVLVEGQEEEFVLSNIAKANLIPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NL1B2_MOUSE
Sequence: MEESQYKQEHNKKVAQDEGQEDKDTIFETIEAIEAKLMELKTNPESTFNYGIFPEVYMNQGEEILYPAWSLKEENLFQTFKSLRLFQKLCPRGSGNLVKKSWYPCVPEEGGHIINIQDLFGPNIGTQKEPQLVIIEGAAGIGKSTLARQVKRAWMEGELYRDHFQHVFFFSCRELAQCKKLSLAELITQGQDVPTAPINQILSHPEKLLFILDGIDEPAWVLADQNPELCLYWSQTQPVHTLLGSLLGKSILPEASFLLTTRTTALQKFIPSLPQSCQVEVLGFSDFEQEIYIYKYFAKQIFGIKALMMVESNPVLLTLCEVPWVCWLVCNCLKKQMEQGGDVSLTSQTTTAICLKYISLTIPVHHMRTQLRALCSLAAEGIWKRRTLFSESDLCKQGLDEDAVAIFLKTGVLQKQASSLSYSFAHLCLQEFFASMSCILEDSEERHGDMEMDRIVETLVERYGRQNLFEAPTVRFLFGLLSKEGLKEMEKLFSCSLPGKTKLKLLWHILGKSQPHQPPCLGLLHCLYENQDMKLLTHVMHDLQGTIVPDTDDITHTVLQTNVKHLVVRTDMELMVVTFCIQFCSHMRSLQLNMEGQQGYALTAPRMVLYRWTPITNASWKILFYNLKFNSNLEGLDLSGNPLSYSAVQYLCDAMIYPGCQLKTLWLVECGLTPTYCSLLASVLSACSSLRELDLQLNDLCDDGVRMLCEGLRNRACNLRILRLDLYSLSAQVITELRTLEENNLKLHISSIWMPQMMVPTENMDEEDILTSFKQQRQQSGANPMEILGTEEDFWGPIGPVATEVVYRERNLYRVQLPMAGSYHCPSTRLHFVVTRAVTIEIEFCAWSQFLDKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVSLKDTKASTFDFKVAHFQEHGMVLETPDRVKPGYTVLKNPSFSPMGVVLRIIPAARHFIPITSITLIYYRVNQEEVTLHLYLVPNDCTIQKAIDDEEMKFQFVRINKPPPVDNLFIGSRYIVSGSENLEITPKELELCYRSSKEFQLFSEIYVGNMGSEIKLQIKNKKHMKLIWEALLKPGDLRPALPRIAQALKDAPSLLHFMDQHREQLVARVTSVDPLLDKLHGLVLNEESYEAVRAENTNQDKMRKLFNLSRSWSRACKDLFYQALKETHPHLVMDLLEKSGGVSLGS
What is the function of this protein?
Constitutes the active part of the Nlrp1b inflammasome.  In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1b (NACHT, LRR and PYD domains-containing protein 1b, N-terminus), preventing activation of the Nlrp1b inflammasome.  In response to pathogen-associated signals, the N-terminal part of Nlrp1b is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1b inflammasome complex: the Nlrp1b inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 1b allele 2.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. SUBCELLULAR LOCATION: [NACHT, LRR and PYD domains-containing protein 1b, C-terminus]: Inflammasome.
Protein: OBG_CLOBH
Sequence: MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTYKRKYKAEPGGNGAGSKCFGKNGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGGRGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLADVGLIGFPNVGKSTLLSVVSKARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVLIHVIDISSVEGRDPYDDFLKINEELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKVEKHGYNKVFKISAATKQGVDDLMKEAARLLSTILVTDLEISEEDRFIEEEKRFTYSIRKEDNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVMEELMEMGIEDGDVVRLNDFEFDFLL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNRPC_MOUSE
Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSSKSGKLKGDDLQAIKKELTQIKQKVDSLLESLEKIEKEQSKQADLSFSSPVEMKNEKSEEEQSSASVKKDETNVKMESEAGADDSAEEGDLLDDDDNEDRGDDQLELKDDEKEPEEGEDDRDSANGEDDS
What is the function of this protein?
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles.  Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.  Single HNRNPC tetramers bind 230-240 nucleotides.  Trimers of HNRNPC tetramers bind 700 nucleotides.  May play a role in the early steps of spliceosome assembly and pre-mRNA splicing.  N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2.
What is the protein family that this protein belongs to?
Belongs to the RRM HNRPC family. RALY subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Component of ribonucleosomes.
Protein: ENO_LACAC
Sequence: MLKSVIENVHALEIFDSRGNPTVEVHVTLSNGVVGKAEVPSGASTGENEAVELRDGGSRLGGKGVSKAVNNVNTEINDALKGMDPFDQPKIDQTMIDLDGTPNKGRLGANAILGVSMATAVAAANANRQPLYRYLGGIDLEMPQTFHNVINGGEHADNGIDIQEFMITPIAKTSFRDGFEKIVNVYHTLKKVLEDMGYETGLGDEGGFAPNMKNSEEALKALHESIIKAGYKPGEDIGIACDCAASYFYNKEDGKYHLEGKVLTDDELAAYYDKLLDEFPELMSMEDPYDENDVEGMVKFTATHKDRIQIVLDDFICTNPALLKKAIKEGAGNASLIKLNQIGTVTETLETIRMSRKNGYNTMISHRSGETGDTFIADLAVAINGGQLKTGAPARSERVEKYNRLLEIEEELGKGERLAFFPDDVDHD
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MYB39_ARATH
Sequence: MGRSPCCDQDKGVKKGPWLPEEDDKLTAYINENGYGNWRSLPKLAGLNRCGKSCRLRWMNYLRPDIRRGKFSDGEESTIVRLHALLGNKWSKIAGHLPGRTDNEIKNYWNTHMRKKLLQMGIDPVTHEPRTNDLSPILDVSQMLAAAINNGQFGNNNLLNNNTALEDILKLQLIHKMLQIITPKAIPNISSFKTNLLNPKPEPVVNSFNTNSVNPKPDPPAGLFINQSGITPEAASDFIPSYENVWDGFEDNQLPGLVTVSQESLNTAKPGTSTTTKVNDHIRTGMMPCYYGDQLLETPSTGSVSVSPETTSLNHPSTAQHSSGSDFLEDWEKFLDDETSDSCWKSFLDLTSPTSSPVPW
What are the official names of this protein?
Transcription factor MYB39, Myb-related protein 39, AtMYB39.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_EHRRW
Sequence: MKLKSIMSQCQFIIGATSIKSLPDFSIPEVALAGRSNVGKSSLINAITNNRKNARISSKPGCTRQINFYLINKGLMVLVDLPGYGYSKADRATVNSYICLMEYYLLNRKNLSKVVLLIDAKVGFKEIDLDFIRWLEVHQILYQLVLTKIDRVQSNVLDVIVSDIQNFNLNFIIYPIINVSSKCKQGIEELIYEIAQCIKK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TRHO_BACCR
Sequence: MATTKPYRVLLYYMYTTIENPEEFAAEHLEFCNSLELKGRILVAKEGINGTCSGTVEQTEKYMEAMNNDPRFDGIVFKIDEADGHAFKKMHVRPRPELVTLRLEDDINPHEITGKYLEPKDFYEAMKQEDTVIIDARNDYEFDLGHFKGAIKPDIESFRELPDWIRENKEVLEGKKILTYCTGGIRCEKFSGWLVREGYEDVSQLHGGIVTYGKDPEVQGELWDGQCYVFDERIAVPVNQKEHVIVGKDHFTGEPCERYVNCSNPECNKKILCSEENEAKYLRACSHECRVSPRNRYVIQHELTEEQVAAALEQIEAGK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GTX3C_NEOIV
Sequence: GWRDWLKKAGGWLKKKGPGILKAALGAATQ
What is the function of this protein?
May have antimicrobial properties, like most ant linear peptides.
What are the official names of this protein?
U1-poneritoxin-Ni3c, U1-PONTX-Ni3c, Poneratoxin, Ponericin Pi I3.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA_CHLT3
Sequence: MEKLVIRGGKPLSGTVSVSGSKNSALAIMAAALLPASGKTVIHRVPNLRDVHTLSNLLRIIGAKVDFEAHTLSIASGDISHYEAPYELVKKMRASIYVLGPLLGRFGRAKVSLPGGCAFGPRPVDLHIESMKKLGADIKLEDGYIIAKTKRKGLSGAKIDFRISSVGATGNTLMAAALAKGTTCLTNAALEPEIVYLCEFLEKMGAKISGIGTTTLEIEGVDELYPIRADNICDRIEAGTLLAAAAITHGNITLTDVDPDHLTAILEKFKEIGCEVSTTETAITLSAPETLLPSNVEALPYPKFPTDMQAQWIALMTQANGISQIIDQVYTERFNHVPELNRLGGEITVKNNMATVHGVKPLSGAKVMSTDLRASASLILAGLAAKGTTEVLRVYHLDRGYESIEKKLRKLGARIRRQTYDEFAQPQLT
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_METS4
Sequence: MAQSSLRLVENPTMDKDKSKAIDAALAQIERAFGKGSIMRLGKGDKVQEVETISTGSLGLDVALGVGGLPRGRVIEIYGPESSGKTTLALHTIAEAQKKGGVCAFVDAEHALDPVYARKLGVNLDDLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDQQPGLQARLMSQALRKLTGSISRSNCMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRVSTLKDRDEPIGNSVRVKVVKNKVAPPFKQVEFDIMFGEGVSKVGELIDLGVKAGIVEKSGAWFSYDSQRLGQGRENAKGFLRDNPDIAGRIEAAIRQNMGLVADKILENAVPTAEDFDEGEA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_PARPJ
Sequence: MARITVEDCLKQIPNRFELALAATYRARQLAQGHTPKIESRDKPTVVALREIAAGQVGVEMLKKVPV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.