PharMolix/UniProtQA huggingface dataset:
Protein: COXX_RHIME
Sequence: MTVIGNHEVVGMEGAPRLSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHINPFIGFTAILCIAIGAGASGALNMWYDADIDAVMSRTAKRPIPAGKILPQEALAFGLTLSAFSVIILGLAVHWLAAGLLAFTIFFYVAIYTMWLKRSTPQNIVIGGAAGAFPPMIGWACVTGGVSVESIVLFLIIFLWTPAHFWALALFKMGDYGAVGVPMMPNVCGEATTKRQIVIYAVLTAVSGVCPTLLGFASLGYGAFATVMGLGFVWYSLGVLRMPEGDKRMVPAKKLFAFSIAYLFAIFSALLVDYAIARIWLGGIV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS2_METMP
Sequence: MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKAEIIYESADLIFHTMVLLAKSGITYEELSEEFKKRMK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_VIBC3
Sequence: MAVQQNRKTRSRRGMRRSHDALTAAALSVDATSGETHLRHNVTAEGYYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: OSGEP_XENLA
Sequence: MTIVVGFEGSANKIGVGIIQDGKVLSNPRRTYITPPGQGFMPSDTARHHRSCILDVLQEALEESNIKPEDVDCVAYTKGPGMGAPLLSVAIVARTVAQLWKKPLLGVNHCIGHIEMGRLITGAENPTVLYVSGGNTQVIAYSERCYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKKGKKFVELPYTVKGMDVSFSGILSYIEDMSHKMLSSGECTPEDLCFSLQETLFSMLVEITERAMAHCGSQEVLIVGGVGCNVRLQEMMGVMCEERGAKIFATDERFCIDNGAMIAQAGWEMFRAGQVTNLQDSWITQRYRTDEVEVTWRD
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Osgep likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, O-sialoglycoprotein endopeptidase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep, tRNA threonylcarbamoyladenosine biosynthesis protein osgep.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IOVO_DACNO
Sequence: IATQVDCSEHPKPACTLDYRPICGSDSKTYSNKCDFCNAVMDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: AMACR_MYCTU
Sequence: MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVTERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHAIGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMVDGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGAIEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGAVFANSDACVTPVLAFGEVHNEPHIIERNTFYEANGGWQPMPAPRFSRTASSQPRPPAATIDIEAVLTDWDG
What is the function of this protein?
Catalyzes the epimerization of (2R)- and (2S)-methylacyl-coenzyme A (CoA) thioesters (PubMed:15632186, PubMed:19854148, PubMed:26348625).  Accepts as substrates a wide range of alpha-methylacyl-CoAs, including (2R)-2-methylmyristoyl-CoA and (2S)-2-methylmyristoyl-CoA, (2R)-pristanoyl-CoA and (2S)-pristanoyl-CoA, and the cholesterol esters (25R)-3-oxo-cholest-4-en-26-oyl-CoA and (25S)-3-oxo-cholest-4-en-26-oyl-CoA (PubMed:15632186, PubMed:26348625).  Can also catalyze the interconversion of the non-physiologic substrates (2R)-ibuprofenoyl-CoA and (2S)-ibuprofenoyl-CoA, which are potential competitive inhibitors of the enzyme (PubMed:19854148).
What are the official names of this protein?
Alpha-methylacyl-CoA racemase, AMACR, MtMCR.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: PCKA_PSE14
Sequence: MTQINNAVHTDLSTDELVKEALARNEGVLSDTGALVVETGHRTGRSPVDRFIVEEPSTQDAIAWGPINRKFPAEKFDALWNRVGAYLAERERFVSHVHVGSDPAHYLPVKMTTETAWHNLFGRCLFINPEQYNPAGKDEWEIQNAPWFVCDPERDGTNSDGTVIINFAARKVLIAGMRYAGEMKKAMFSVQNFLLPASDVLPMHCAANMGEEGDVTLFFGLSGTGKTTLSADESRYLIGDDEHGWGEGVVFNIEGGCYAKCIDLSEKNEPVIWKAIQHGAVLENVVLDPVTKKADYADSSLTQNSRAAYPRELIEKRAPKNLGGEPNAVIFLTCDLTGVLPPVSILSEEQAAYHFLSGYTALVGSTEMGSGSGIKSTFSTCFGAPFFPRPAGEYAELLIKRIRGFKSKVYLVNTGWTGGGYGVGKRFNIPTTRGVVAAIQSGALIGAETEHLDTINLDVPKSVPGVDTGLLNPRNTWADKAAYDEAAKALAGLFVENFKKFDVSDAIKAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_BOVIN
Sequence: MALRYPMAVGLNKGHKVTKNVGKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: PTH_HELPS
Sequence: MTLLVGLGNPTLRYAHTRHNAGFDILDSLISELDLSFTFSSKHNACLCVYKDFILLKPQTYMNLSGESVLSAKNFYKTEELLIVHDDLDLDLGVVRFKNGGGNGGHNGLKSIDLLCSNSYYRLRVGISKGMGVIEHVLSKFHKNEEPLKNAAFEHAKNALKFFIESHDFNAMQNRFTLKKPLKIES
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_RICCN
Sequence: MTNNLSGYRNKFVRVKTSKKRTVSSSNWLRRQLNDPYVAKARIDGFRSRAAYKLLEIHEKFKLFTPNMKIVDLGAAPGGWSQVASKLIKASDNNLNNKIISIDVLEIEHVAGVEFVQKDFFEADTEELIIQALDGRADIVMSDMASNTIGHKATDHIRTLLLCEQAFEFALKVLKPSGHFIAKIFRGGAENELLHKVKREFKTVKHFKPSSSRSESTEIYLVALNKK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAP1_HUMAN
Sequence: MASSRCPAPRGCRCLPGASLAWLGTVLLLLADWVLLRTALPRIFSLLVPTALPLLRVWAVGLSRWAVLWLGACGVLRATVGSKSENAGAQGWLAALKPLAAALGLALPGLALFRELISWGAPGSADSTRLLHWGSHPTAFVVSYAAALPAAALWHKLGSLWVPGGQGGSGNPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQLLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEKIFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQAPADAPE
What is the function of this protein?
ABC transporter associated with antigen processing.  In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PubMed:25656091, PubMed:25377891).  Uses the chemical energy of ATP to export peptides against the concentration gradient (PubMed:25377891).  During the transport cycle alternates between 'inward-facing' state with peptide binding site facing the cytosol to 'outward-facing' state with peptide binding site facing the ER lumen.  Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to hydrolysis-competent 'outward-facing' conformation ready for peptide loading onto nascent MHCI molecules.  Subsequently ATP hydrolysis resets the transporter to the 'inward facing' state for a new cycle (PubMed:25377891, PubMed:25656091, PubMed:11274390).  Typically transports intracellular peptide antigens of 8 to 13 amino acids that arise from cytosolic proteolysis via IFNG-induced immunoproteasome.  Binds peptides with free N- and C-termini, the first three and the C-terminal residues being critical.  Preferentially selects peptides having a highly hydrophobic residue at position 3 and hydrophobic or charged residues at the C-terminal anchor.  Proline at position 2 has the most destabilizing effect (PubMed:7500034, PubMed:9256420, PubMed:11274390).  As a component of the peptide loading complex (PLC), acts as a molecular scaffold essential for peptide-MHCI assembly and antigen presentation (PubMed:26611325, PubMed:1538751, PubMed:25377891).
What are the official names of this protein?
Antigen peptide transporter 1, APT1, ATP-binding cassette sub-family B member 2, Peptide supply factor 1, Peptide transporter PSF1, PSF-1, Peptide transporter TAP1, Peptide transporter involved in antigen processing 1, Really interesting new gene 4 protein, RING4.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=The transmembrane segments seem to form a pore in the membrane.
Protein: LPTD_YERPE
Sequence: MKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFLIPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADNASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQPASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL1_SYNP6
Sequence: MTRKVSRRLQELQKKVEDRAYEPLAALNLLKETATAKFPESAEAHIRLGIDPKYTDQQLRTTVALPKGTGQTIRVAVIARGEKVAEAKAAGADIAGSEELIEEISKGFLDFDLLIATPDVMPQVAKLGRQLGPRGLMPSPKGGTVTFDLEQAVNEFKAGKLEFRADRTGIVHVLFGKASFSADDLLANLKALQETIDRNRPSGAKGRYWRSVYISATMGPAIEVDINALRDPKLAEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RSMA_RHILW
Sequence: MAALDGLPPLRDVIQRHGLDARKALGQNFLLDLNLTQKIARTAGALEEATIFEVGPGPGGLTRAILALGARKVIAVERDTRCLPALAEIADHYPGRLEVIEGDALKTDFEALAPDGPIKIIANLPYNVGTQLLVNWLLPKAWPPFWQSLTLMFQKEVGERIVASEDDDHYGRLGVLCGWRTQTRMAFDVPPQAFTPPPKVTSTVVHLTPRENPIPCAVGDLEKVTQAAFGQRRKMLRQSLKPLGGERLLVKAGIDPARRAETLSVEEFCLLANSL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_NEPOL
Sequence: METPALVATVFVSCLVLSITGYSLYIGFGPPSKELRDPFDEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RSMA_METMA
Sequence: MVRSILKKYNIKGGTFDQHFLIDAGYLDRIVAAAELSPQDTVLEIGAGIGNLTERLARRAKKVIAVELDPALVSVLHDRFDAAENIEIIAGDALKVDFPEFDKVVSNLPYSISSEITFKLLRHKFKLGVLMYQYEFAVRMVSPPGCKDYSRLTIDTCYFADASIVMKVPKGAFQPAPEVDSAVIKLIPRPAPFEVRDETFFLQFVAAVFSQRRKKLRNAILNTSSLLKIPDIKEIVSQLPEDFMNKRAEDLTPEELASVANMIFDLKSRNF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPQH_MYCBP
Sequence: MKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
What is the function of this protein?
Might be involved in ligand transport.  A host TLR2 agonist, modifies host gene expression in response to pathogen.
What are the official names of this protein?
Lipoprotein LpqH, 19 kDa lipoprotein antigen, Putative transporter LpqH.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial 19 kDa antigen family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Host cytoplasm. Extracellular vesicle, bacterial extracellular vesicle. Note=Following infection of mouse macrophage cell line J774A.1 by live (not heat-killed) bacteria the protein is detected in host cytoplasm at 1 hr but has decreased dramatically by 3 hrs (PubMed:11123323). Also present in bacterial extracytoplasmic vesicles, both in mouse macrophages and in culture media (PubMed:21364279).
Protein: FABH_CROS8
Sequence: MYTKIIGTGSYLPEHVRTNADLEKMVETSDEWIVTRTGIRERRIAAPGETVATMGYEAALRAIDMAGIDKGQIGLIIVATTSATHAFPSAACQVQGMLGIKGCPAFDVAAACAGFTYALSIADQYVKSGAVNNALVIGSDVLARTLDPEDRGTIILFGDGAGAVVLGASEEPGILSTHLHADGSYGELLTLPNQDRVNPDSPTFLTMAGNEVFKVAVTELAHIVDETLEANKLDRADLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_PSE14
Sequence: MTDRIELTTANEFIARHIGPRAADEQAMLQTLGFDSIEALSESVIPESIKGTSVLNLPAGQSEADALASIKAIASKNQLFKTYIGQGYYNTHTPAPILRNLLENPAWYTAYTPYQPEISQGRLESLLNFQTLISDLTGLPIANASLLDEATAAAEAMTFCKRLSKNKGSQQFFASSHCHPQTLDVLRTRAEPLGITVVVADEAELGDVSDYFGALLQYPASNGDVFDYRELVERFHAANALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFSTRDAFKRDMPGRLVGVSVDRHGKQALRLAMQTREQHIRREKATSNICTAQVLLANIASMYAVYHGPRGLTQIAKRVHQLTAILAEGLSTLGLKAEQAFFFDSLTLNTGSRTAALHAAARARHINLREIDDQHLGLSLDETTSQSAVETLWEIFASDGQNLPDFTALAASVPSRLPATLLRQSAILSHPVFNRYHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGNLHPFAPAEQSTGYQQLTDELEAMLCAATGYDAISLQPNAGSQGEYAGLLAIRAYHQSRGDEHRDICLIPSSAHGTNPATANMAGMRVVVTACDARGNVDIEDLRAKTVQHRDQLAAIMITYPSTHGVFEEGIREICGIVHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLAPFMPGHARMERKEGAVCAAPFGSASILPITWMYIRMMGGEGLKRASQLAILNANYISRRLEEHYPVLYTGTNGLVAHECILDLRPIKDSSGISVDDVAKRLIDFGFHAPTMSFPVAGTLMIEPTESESREELDRFCDAMIKIREEIRAVENGTLDKDDNPLKNAPHTAAEIVGQWSHPYSREQAVYPVDSLIENKYWPPVGRVDNVFGDRNLVCACPSIESYQEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: NAGB_ECOL6
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIEAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RUVA_FRATM
Sequence: MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQLYGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVIEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GN_SHV21
Sequence: MTWKLFICFLSFGVIFLRVSSLTEKSHTTSYTILHNNNFYSNSCSADTYVPSIKTFSSVWAILNVIIFFCASLFYLRHLCIVKFISNLTK
What is the function of this protein?
Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity.  Also plays a critical role in virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein N.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein N family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=When coexpressed with gM, localizes in the host trans-Golgi network.
Protein: Y049_METMJ
Sequence: MLGGGLVGLAILFFVLALIFAILGARGVAGMSMSVAKWLVIIFIVLAIISLLL
What are the official names of this protein?
UPF0391 membrane protein Memar_0049.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN888_HUMAN
Sequence: MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMEFSSIGKGNTEVIHTGTLQRLASHHIGECCFQEIEKDIHDFVFQWQEDETNGHEAPMTEIKELTGSTDQYDQRHAGNKPIKYQLGSSFHSHLPELHIFQPEGKIGNQLEKSINNASSVSTSQRISCRPKTHISNNYGNNFFHSSLLTQKQDVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRIHTGEKPFKCSECGKAFRAQSTLIHHQAIHGVGKLD
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 888.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYB4_RAT
Sequence: MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
What is the function of this protein?
Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.
What are the official names of this protein?
Thymosin beta-4, T beta 4.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.