PharMolix/UniProtQA huggingface dataset:
Protein: GOLS5_ARATH
Sequence: MTMTVEKRIEADVTVSHEGVERAYVTFLAGNKDYWMLVVGLAKGLRKVKSAYPLVVATLPDVPEEHRQILVDQGCIIRDIEPVYPPENTTGYSMAYYVINYSKLRIWEFVEYEKMIYLDGDIQVFKNIDHLFDTPRGYLYAVKDCFCEVSWSKTPQYKIGYCQQSPEKVTWPVESLGAPPPVYFNAGMLVFGPNLVTYEDLLRVVQITTPTYFAEQDFLNIYFRDIYKPIPSTYNLVMAMLWRHPEHIDLDQISVVHYCANGSKPWKFDEAEEHMDREDIKMLVKKWWEIYEDSSLDYKNFVETESKLNPVTATLASKKLVGDVLTSLAPSAA
What is the function of this protein?
Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants.  May promote plant stress tolerance (By similarity).
What are the official names of this protein?
Galactinol synthase 5, AtGolS5, GolS-5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Galactosyltransferase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O1622_CONCL
Sequence: MKLTCVLIVAVLILTACQVIAADEADANRLSTRWCACGVNYYCCNEVCTWREDPCP
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.22, O1_cal6.22.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2190_CLOBK
Sequence: MEEIVEMSLLLDFYGSLLTEKQNKIMDLYYNNDYSLKEISELTNTSRQAVHDIVKRCHKALLQYEEKLHMMERFINLENSKEKLLNMLNKVTKENIKEIDHIKKYIIDNI
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein CLD_2190.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: GATA_CROS5
Sequence: MTSIRELHQQLVNKERSAVEITTEALERINAVDSKVKSFLQVTADHALETAKKVDEKIAKNEEIGLLAGIPIGIKDNMCTTGIKTTCGSKILANFVPPYESTVTQKLKDAGAVMVGKTNLDEFAMGSSTENSGYQVTANPWDLSRVPGGSSGGSAAAVAASECVVALGSDTGGSIRQPASLCGVVGLKPTYGLVSRFGLVAYASSLDQIGPFARNVQDAAILLGAIAGYDPKDSTSINTPVPDYTQFLKPSLEGLTIGVIEETFGEGLDPVVSKTVKAAIDHLKTLGAKVVNVSCPRFRYGLPAYYIIAPSEASSNLARYDAVKYGIREDADTLIDMYTKTRAVGFGNEVKRRIMIGTYTLSAGYYDAYYLKAQKVRTLIKQDFDAGFEKVDVLVCPTSPTTAFKAGEKTSDPLSMYLSDLTTIPVNLAGLPGMSIPCGFDDNNLPVGLQLIGNVLEEGKLFQVAYAYEQSTDWHNQVPPLQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ACT6_DROME
Sequence: MCDDDAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
What is the function of this protein?
Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin, indirect flight muscle, Actin-88F.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NU4LM_ACACA
Sequence: MTSFNIFFLLFFSFVIFFLGILGIFITRKNIIIILVSIELMLLAVNFNFAIFSVLLEDMFGQVFILYTLTLAGAEAAIGLAILIIFYRIRGIISVNFVTSLKG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PYRH_SERP5
Sequence: MATNAKPVYQRILLKLSGEALQGAEGFGIDASVLDRMAQEVKELVELGIQVGVVIGGGNLFRGAGLAQAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDNYSWAEAISLLRNNRVVIFSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVYSADPVKNPDATLYEHITYQDVLERELKVMDLAAFTLARDHGLPIRVFNMNKPGALRRVVMGENEGTLISK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_HAMD5
Sequence: MSRVCQVTKKRPVTGNRRSHAMNATKRRFLPNLHRHRFWIESEKRFITLRLSAKGIRIIDKKGIEAVLEEIKARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RIC3_HUMAN
Sequence: MAYSTVQRVALASGLVLALSLLLPKAFLSRGKRQEPPPTPEGKLGRFPPMMHHHQAPSDGQTPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTTAEDGKCYTAMPGNTHRKITSFELAQLQEKLKETEAAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDRFSPEKEAEEAPYMEDWEGYPEETYPIYDLSDCIKRRQETILVDYPDPKELSAEEIAERMGMIEEEESDHLGWESLPTDPRAQEDNSVTSCDPKPETCSCCFHEDEDPAVLAENAGFSADSYPEQEETTKEEWSQDFKDEGLGISTDKAYTGSMLRKRNPQGLE
What is the function of this protein?
Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors (PubMed:12821669, PubMed:15504725, PubMed:16120769, PubMed:18691158, PubMed:32204458).  May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
What are the official names of this protein?
Protein RIC-3, Resistant to inhibitor of cholinesterase 3.
What is the protein family that this protein belongs to?
Belongs to the ric-3 family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
Protein: SYD_BACTN
Sequence: MFRTHTCGELRISDVNKQITLSGWVQRSRKMGGMTFIDLRDRYGITQLVFNEEINAELCDRANKLGREFVIQITGTVNERFSKNANIPTGDIEIIVSELNVLNTAMTPPFTIEDNTDGGDDIRMKYRYLDLRRNAVRSNLELRHKMTIEVRKYLDSLGFIEVETPVLIGSTPEGARDFVVPSRMNPGQFYALPQSPQTLKQLLMVSGFDRYFQIAKCFRDEDLRADRQPEFTQIDCEMSFVEQEDIISTFEGMAKHLFKTLRGVELTEPFQRMPWADAMKYYGSDKPDLRFGMKFVELMDIMKGHGFSVFDNAAYVGGICAEGAATYTRKQLDALTEFVKKPQIGAKGMVYARVEADGTVKSSVDKFYTQEVLQQMKEAFGAKPGDLILILSGDDVMKTRKQLCELRLEMGSQLGLRDKNKFVCLWVIDFPMFEWSEEEGRLMAMHHPFTHPKEEDIPLLDTDPAAVRADAYDMVVNGVEVGGGSIRIHDAQLQARMFEILGFTPEKAQAQFGFLMNAFKYGAPPHGGLAYGLDRWVSLFAGLDSIRDCIAFPKNNSGRDVMLDAPSEIDQTQLDELNLIVDIKENK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_CHLPD
Sequence: MANPKAKMSKSRRDKRRAQFNARTKPVTTVNCPNCGEPTLPHRACRHCGHYRGRAVTGKTANG
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SFG1_YEAST
Sequence: MDEMHSSDTLLLRTPKSKKKIGLVIPSTPSKKCKYSSGFIAEDTTPSKRFRLYQAKFKTSSKNVKAQTLSVSIKKNQGEITNPFMTEGYNDYRNIVSPGLSFDNDCFSEHELVSPLSDISSINSTSPDVEKIDSLDPFGVDSFVWNCKPLVNKEALELHRMIHSSFPMSPLESNSDVPLLLPKLKKRLSPVNRSTFKPTRYEPSHRLLKPKKSILTVPAKSLNLIVSSSRGSLNDATIFATEINSTLSNEENKLPAISSIWEKLTIPVNSSIKEKYKKLKDQIYGQASNFGEDEDNEEDNEDDLPDAAVIRGYEFQSGRRDELTQCNELQSTKDYKKVQWAKVLEQ
What is the function of this protein?
Probable transcription factor required for superficial pseudohyphal development in response to nitrogen starvation.
What are the official names of this protein?
Superficial pseudohyphal growth protein 1.
Protein: HLDD_RHILO
Sequence: MIIVTGGAGMIGSNIVAALNAEGHDDILVVDDLTDGHKIANLADLSIADYLDKDDFLTRIEAGALGRIEAVFHQGACSTTTEWNGKFMMEVNFAYSKRLLHACQAPRVPFLYASSASVYGGGSEFREEPALERPLNVYAYSKKLFDDYVRRTVFDTDHSQVAGLRYFNVYGPREAHKGAMASVAFHLFNQVERGENPRLFGAYDGFGPGEQSRDFIHVGDVADVNLWLWKRGSSGIFNCGTGRAQPFRAIAETVIDTLGKGEIEFIPFPDHLKGSYQSFTQADMSRLRAAGYNGQFRTVETGVRDYVEWLKAQRSS
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RS3A_METAC
Sequence: MARKKVQRKLDGWKSKEWYNIEAPVYLNRAIVGNTMAGDPSLLVGRNVETTVGELTNDMTKNNTKVILRINNVVGDIATTDLMGHELTTDYIRSIVKRQTSRIDANVDVKTKDGYVIRVKPTCFTIKRARSSQMQAIREMMVEIVKKRAAESDFETFMQEAILGRLSAAIYRQAKFIYPLRRVEIRKTEVETIPAAAPAPAAA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: EX7L_RICAH
Sequence: MLENFIANQATKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIASSGHAYFNLKENTAILACTCWRPILAKIKFPLNDGIEVVISGKLSSYAGNSRYQLSVDNLQPAGLGAMLQILNDRKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDIIHRIRERFPTRIIIWPVSVQGENSSNEIAEAIEGFNNLAEVNKPSVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISAVGHEVDYTLIDLAADKRAPTPTAAAEFAVPVRSILNNTLHSYEKILLNNTSRLIKYHEHNIINYDKIHRYLSHYMDNRQQLLDETGFNLLDALLCFIELQETKIKSFSKERVNPAKILNYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYNNVLKRGFAIVKGETGNFLSSKIAAANEKIFNIKFSDGEIKVVRN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BORBR
Sequence: MYKLVLMRHGESQWNLENRFTGWTDVDLTETGREQARKAGELLKREGYAFDLAYTSVLKRAIRTLWIALDAMDAMYTPVGINWRLNERHYGQLQGLNKAETAAKYGDEQVLIWRRAYAIAPEPLDLEDPRHPRFDGRYAKIPADQLPATECLKDTVARVLPFWNESIAPAIRAGRRVLVAAHGNSLRALIKHLDNVSDDDIVGVNIPTGQPLVYELDEDLKPIRHYYLGDAAEIEAAMAAVAAQGKAKKD
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MURC_RICPU
Sequence: MLLLELKKTNQTLETIHFIGIGGVGMSGIAEILYNLGYKVQGSDLVENYNTKRLESYGIKIFLGHAEQNITNVSYVVISSAINPKNPEIKEALERKIPIIRRADMLAELMRLKCSVAVSGSHGKTTTTSLVACLFEAAGLCPTVINGGIINNKLTNAYLGSSNYLIAEADESDATFIHIPSTIAIITNIDPEHLDYYRDFETLIGAFRSFITNLPFYGFAVCCIDHKIVRKLVDEITERKIVTYGIDSEDAHIIAFNINTDIASSTFDVKISLPNVLGTTIIEKITIPTPGRHNILNSLAAIAVGIELDFGIKAIKNGFNNFKGVKRRFTKVAEYNNASIIDDYAHHPEEIKATLATAKNIANKQNGKVIAIFQPHRYSRMQYLFDDFMLCFADADILYITDIYAAGENPIEGITGRSLVDKITKRKHHDKANFLAELDDAVGVIIDNAASGDMIIMMGAGNISSFANELDGRLSSSGFSCHTVV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFJL_BACSU
Sequence: MKKLVFGLLAIVLFGCGLYIYHVWFGDPFSKNAAEQKLVSYVKQTYPKKEIKITNGVYNAKTSEYVFEATSQSHRYPMCTKGFLHPKVTCDGIEEAYTESVAKHVNEEATKAIEADLKKAVPRFIKADAALSIENGQFTLDTKWNKKLAEKAPMSMTIQLDASGLSKTDAAKMAETVRKTLNEKGYTYSNGTIDCMQKDGDGGIGYVKYSIDFLSKAAIQSNDAEELGS
What are the official names of this protein?
Uncharacterized protein YfjL, PSPB19'.
Protein: ATPD_PROMS
Sequence: MPLLNSVTTPYAEALLQVVNENSQTEEMVSEVKQLLELVNDSPELEKALSSPILETDAKKKIIIEIFSNKVNSSLLNFLKLLADRQRIGILTSILDRFLEIYRENSNIALATVTSAVELTDEQKGLITKKIINIAGTEKLELVTKIDPSLIGGFVASVGSKVIDASLASQIRKLGLTLSK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: SKP2_MOUSE
Sequence: MHRKHLQEIPDQSGNVTTSFTWGWDSSKTSELLSGMGVSALEKEEVDSENIPHGLLSNLGHPQSPPRKRVKGKGSDKDFVIIRRPKLSRENFPGVSWDSLPDELLLGIFSCLCLPELLRVSGVCKRWYRLSLDESLWQSLDLAGKNLHPDVTVRLLSRGVVAFRCPRSFMEQPLGESFSSFRVQHMDLSNSVINVSNLHKILSECSKLQNLSLEGLQLSDPIVKTLAQNENLVRLNLCGCSGFSESAVATLLSSCSRLDELNLSWCFDFTEKHVQAAVAHLPNTITQLNLSGYRKNLQKTDLCTIIKRCPNLIRLDLSDSIMLKNDCFPEFFQLNYLQHLSLSRCYDIIPDTLLELGEIPTLKTLQVFGIVPEGTLQLLREALPRLQINCAYFTTIARPTMDSKKNLEIWGIKCRLTLQKPSCL
What is the function of this protein?
Through the ubiquitin-mediated proteasomal degradation of viral proteins may have an antiviral activity.
What are the official names of this protein?
S-phase kinase-associated protein 2, Cyclin-A/CDK2-associated protein p45, F-box protein Skp2, F-box/WD-40 protein 1, FWD1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YOW7_CAEEL
Sequence: MHANPTEETNILYFKFFSGRSIQVGNNRKSCKKLPDFEYISKGGIRCCIIHFFKIYFTPEMFFHLNDFPKLDNSGNETFILSRSLWVRFFLLVQLLVLCKNLNGKLKSK
What are the official names of this protein?
Uncharacterized protein ZK643.7.
Protein: ISLR2_MOUSE
Sequence: MGPFGALCLAWALLGVVRACPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQGVPVHRLPALPCAPPSVRLSAEPPPEAPGTPLRAGLAFMLHCVAEGHPTPRLQWQLQIPGGTVVLVPPVLSKEEDGGDKVEDGEGDGDEDLPTQTEAPTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDAQVPTSERKATTKGRSNSVLPFKPEGKTKGQGLARVSVLGEIEAELEETDEGEQMEGQIPADPMGEKHCGHGDPSRYVSNHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAARWGPGPDGASGARRPGRRPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPEEGLDEDVEQGDPSGDLQREESLAGCSLVESQSKANQEEFEAGSEYSDRLPLGAEAVNIAQEINGNYRQTAG
What is the function of this protein?
Required for axon extension during neural development.
What are the official names of this protein?
Immunoglobulin superfamily containing leucine-rich repeat protein 2, Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AROE_ECOL6
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNTFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIHALGMDELEGHEFDLIINATSSGISGDIPAIPPSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRTADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: DUT_METAC
Sequence: MTLLSSNELRKLIQATPHLLENAVDIETQIQPNGLELTLKEIKTIEGVGAVDFDNSERKVPDAKPLEFEDDDWIHLPKGIYKVIFNEIVNIPMNLAAIAKPRSSLIRCGATLETAVWDAGYRGRSESMLVVYNSAGFRLKKNARIMQLLFYTLNSEVEEGYSGVYQNENTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Probable deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family. Archaeal dUTPase subfamily.
Protein: ASSY_SYNP2
Sequence: MGRAEKVVLAYSGGVDTSVCIPYLMHEWGVKEVITLAADLGQGEELGPIKQKALNSGAVVSLVEDGREEFITDYAFPAIKANALYENRYPLATALARPLIAKMLVRAAEKYGADAVAHGCTAKGNDQVRFDLGILAQNPEIKVLAPAREWGMSREEAITYGEQYGLTFPVKKSSPFSIDKNLLGRSIEAGPLEDPMCEPPEEVFEMVKAISDTPDEPEYLEIGFEKGVPVMVNGEALGPVALISKLNEIVGNHGIGRIDMIENRVVGIKSREIYESPAMCVLVDAHRDLESLTLTADVTQYKRGMEQTYSELIYRGLWFSPLKQAVDAFIEQTQERVTGVVRLKLHKGTARIVGRRSEKSIYTPDLATYGADDKFNHESAEGFIYIWGLPTRVWAQANK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A2M_HOMAM
Sequence: SYIITTPRMWVAGSPAQVRTYVMPYGCGEQNMVNFAPN
What is the function of this protein?
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism.  This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases.  When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase.  The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced).  Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
What are the official names of this protein?
Alpha-2-macroglobulin homolog, Alpha-2-M.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACDA2_METTE
Sequence: MAKLTTGSFSIEDLESVQITINNIVGAAKEAAEKAEEELGPMGPTPFPTAATVRDWSFTLFDRYEPVYTPMCDQCCYCTFGPCNLEGNRRGACGLDMKGQAAREFFLRCITGCACHSAHGRHLLDHIISIFGEDMPINMGASNVIAPNIQLITGRQPKTLGDLKPIMEYVEEELGQLLATVHAGQEGAAIDYDNKAMLAGILDHVGMEVSDIAQVTALGFPKSDPEAPLVEVGMGTLDASKPVIIAIGHNVAGVTYIMDYMEDNNLTDKMEIGGLCCTAFDMTRYKREDRKPPYAKIVGTISKELKVVRSGIPDVIVIDEQCVRADLVEEGKKLKIPVIASNEKVMYGLPDRTNDDVDAIIEDIKTGKIPGCVMLDYEKLGELVPRLAMEMAPLREGISAIPSDEEMASLVAKCVACGECALACPEELDIPDAIQAAKEGDFTALDFLHDLCVGCRRCEQVCNKEIPILSVIDKAAQKAIAEEKGLVRAGRGQVSDAEIRAEGLNLVMGTTPGVIAIIGCANYPAGSKDVYRIAEEFLNRNYIVAVSGCSAMDIGMYKDADGKTLYERFPGRFERGNILNTGSCVSNSHISGTCHKVAAIFAGRNLSGNLAEIADYTLNRVGAVGLAWGAYSQKAAAIGTGCNMYGIPAVLGPHSGKYRRALIAKTYDENKWKVYDSRNGSELDIPPSPEFLITTAETWQEACVLLAKNCIRPSDNNMGRSIKLTHWIELSEKYLGVLPEDWWKFVRHEADLPLSRREELLKKLETEHGWEIDWKKKKIISGPKIKFDVSSQPTNLKRLCKEA
What is the function of this protein?
Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit alpha 2, ACDS complex subunit alpha 2, ACDS complex carbon monoxide dehydrogenase subunit alpha 2, ACDS CODH subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: RL7_PELUB
Sequence: MPDLNKIIEDLSSLTVVEAAELSKQLEEKWGVTAMAAAAPAAAAGGAAEEAKDDFTIMLISAGDKKINVIKEVRAATSLGLKEAKDLVEGAPKEVKSGVNKKDAEEIKAKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ZMIZ2_HUMAN
Sequence: MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTTVWGVGNATQSQVLGNPMGPAGSPSGSSMMPGVAGGSSALTSPQCLGQQAFAEGGANKGYVQQGVYSRGGYPGAPGFTTGYAGGPGGLGLPSHAARPSTDFTQAAAAAAVAAAAATATATATATVAALQEKQSQELSQYGAMGAGQSFNSQFLQHGGPRGPSVPAGMNPTGIGGVMGPSGLSPLAMNPTRAAGMTPLYAGQRLPQHGYPGPPQAQPLPRQGVKRTYSEVYPGQQYLQGGQYAPSTAQFAPSPGQPPAPSPSYPGHRLPLQQGMTQSLSVPGPTGLHYKPTEQFNGQGASFNGGSVSYSQPGLSGPTRSIPGYPSSPLPGNPTPPMTPSSSVPYMSPNQEVKSPFLPDLKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLRDSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSGTIPGTPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVKPDMHIKEEPDGPALKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSSFLGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTACLPSQMAPAGHLDPTHNPGTPGLHTSNLGAPPGPQLHHSNPPPASRQSLGQASLGPTGELAFSPATGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYLGPPDLPTNNNDDLLSLFENN
What is the function of this protein?
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
What are the official names of this protein?
Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7.
Protein: FER2_DESVM
Sequence: MAKYLYLDQDECMACESCVELCPEAFRMSSAGEYAEVIDPNTTAECVEDAISTCPVECIEWREE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-2, Ferredoxin II, FdII.
Protein: PDXS_STAA2
Sequence: MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.