PharMolix/UniProtQA huggingface dataset:
Protein: RIBA_BUCAP
Sequence: MQLIQIEKAILPTPWGDFLIFGFEEKKNGKNHIALVYGKIKKNIPILARIHSECLTGDAFFSLRCDCGIQLEMAMSRIASEGNGILIYHRQEGRNIGLLNKIKAYSLQDKGLDTVEANQKLGFSADERDFSLCADIFNILNIKKIRLLTNNPFKVDMLIASGIEIVERIPIIVEKNDKNAHYLKTKAEKMGHLLFK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: BUP1_ARATH
Sequence: MDHMISENGETSAEGSICGYDSLHQLLSANLKPELYQEVNRLLLGRNCGRSLEQIVLPESAKALSSKHDFDLQAASFSADKEQMRNPRVVRVGLIQNSIALPTTAPFSDQTRGIFDKLKPIIDAAGVAGVNILCLQEAWTMPFAFCTRERRWCEFAEPVDGESTKFLQELAKKYNMVIVSPILERDIDHGEVLWNTAVIIGNNGNIIGKHRKNHIPRVGDFNESTYYMEGDTGHPVFETVFGKIAVNICYGRHHPLNWLAFGLNGAEIVFNPSATVGELSEPMWPIEARNAAIANSYFVGSINRVGTEVFPNPFTSGDGKPQHNDFGHFYGSSHFSAPDASCTPSLSRYKDGLLISDMDLNLCRQYKDKWGFRMTARYEVYADLLAKYIKPDFKPQVVSDPLLHKNST
What is the function of this protein?
Catalyzes a late step in pyrimidine degradation.  Converts N-carbamoyl-beta-aminoisobutyrate and N-carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide.  Involved in the recycling of nitrogen from nucleobases to general nitrogen metabolism.
What are the official names of this protein?
Beta-ureidopropionase, N-carbamoyl-beta-alanine amidohydrolase, Protein PYRIMIDINE 3.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BUP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_ACIB3
Sequence: MAIKSDRWIREMSEKHGMIEPYAENQVRFDKNGEKLISYGVSSYGYDVRCAREFKVFTNVHSAIVDPKNFDEKSFIDIESDVCIIPPNSFALARTIEYFRIPRNVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPARIYAGEGVAQMLFFESDEVCETSYKDRGGKYQGQTGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: GLPK_CERSK
Sequence: MNHILAIDQGTTSSRAMVFDEALTLKSVAQEEFPQIYPRPGWVEHDPSDLWSSVAATARAAVERAEIDGSLAAIGITNQRETVVVWERASGHPIHNAIVWQDRRTADLCHALAEAGHEPTITERTGLLLDPYFSATKLKWLLDHVEGARARARRGELLFGTVDSYLIWKLTGGRAHVTDATNAARTMLFDIGRGIWDPEICGLLDIPMEMLPEVKDCAALFGMTRADLFGREIPILGVAGDQQAATCGQACFRPGMMKSTYGTGCFALLNTGEERVTSRARLLTTIAYQLGGKRTYALEGSIFIAGAVVQWLRDGLKIIREAGETQGLALSSDAAQDLVIVPAFTGLGAPWWKPESRGAVFGLTRNSGPAEFARAALESVGYQTRDLLEAMRADWAAGAEGVLRVDGGMAASDWSMQFLADIIGAPVDRPVVRETTALGVAWLAGMQAGLCPGPEEFAADWALERRFEPQMEASVREAKYDRWGRAVRAVMAV
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: VM1B2_BOTJR
Sequence: TELPKGAVQPKYEDAMQYEFKGNGEPVVLHLEKNKGLFSEDYSETHYSPDGRQIITYPPFEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWESYEPIKKASPSNLTPEQQKFSPRYIEVAVVADHRMFKKYNSNLNTIRKWVHEMVNSMNGVYRSMDVHLSLANLEVWSKKDLINVQKDSRETLKSFGEWRERDLLPRISHDNAQLLTAVVFDQQTIGRAYIAGMCDPRHSVGVVMDHSKENLQVAVTMAHELGHNLGMEHDENQCHCDAPSCVMASVLSVVLSYEFSDCSQNQYQTYLTKHNPQCILNEPLLTVSGNELLEAGE
What is the function of this protein?
This metalloproteinase displays proteolytic activity on fibrin, fibrinogen, collagen, casein and gelatin.  It inhibits ADP- and collagen-induced platelet aggregation and displays a very low edema inducing activity.
What are the official names of this protein?
Snake venom metalloproteinase BjussuMP-2, SVMP, BOJUMET I, BjussuMP-II, Nonhemorrhagic metalloprotease MP-II.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BR21_AMOMA
Sequence: MFTMKKSLLVLFFLGTISLSLCEEERNADEDDGEMTEEEKRGLLSTFKQVGISALQGAAQGLLNTLSCKIAKTC
What is the function of this protein?
Antimicrobial peptide.  Active against a variety of Gram-negative and Gram-positive bacterial strains.  Active against fungi.  Shows hemolytic activity against human erythrocytes.
What are the official names of this protein?
Brevinin-2MT1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: DAPH_STAA9
Sequence: MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: SF3B5_HUMAN
Sequence: MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLMEKMLQPCGPPADKPEEN
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:27720643, PubMed:28781166).  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).
What are the official names of this protein?
Splicing factor 3B subunit 5, SF3b5, Pre-mRNA-splicing factor SF3b 10 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SF3B5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDI1_ASHGO
Sequence: MNVTVSNEVTDELLGPFELSDDITLMDFMALIDFDENEQALWHNMRQLKSVDREKTLMQLGIVGESLVVVKAIKKKATEGSTTRASKASAKAAKAAAKAAAVARDTPAEQATTVSPVAQVPVAVSPAVTAAVPTQPTSPSGGPAAANDIITPEDEYIETFRKSLLNSPSLASNIPIPGVNQLIQDSQLFKQLIGPVLLHRRAQQQAANQMGTAQSEYVKLMSNPDDPSNQARISELINQQEIDEQLHKAMEYTPEVFASVNMLYINMEINGHPVKAFVDSGAQSTIMSTALAERTGLGRLVDKRFRGIARGVGKGEIIGRVHAAQVKIETQFIPCSFIVLDTNVDLLLGLDMLRRYQACVDLKENVLKIAGIVTPFLPEAEIPKHFDMDPSAEATNLPSTSPLGNQKAAPEARDAGVGSALLNRSTPATAERTHAEEDVRRLMDLGFSRAEVLKALDHSQGNAEYAAAFLFQ
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPCH_AERSO
Sequence: MNKPVTLLLATLLAPLSGQLCAQESVTMDGKQYSTIEVNGQTYLIPDNGSKKRVARSLDSKVPQQTLRRGDVLMQGAASPELTVSGTLLVEADDASAKALATRHGLNFKQSSGGIALLEAKPGTDLNAIATKLKSEGVNVQIELSGAEQQPK
What is the function of this protein?
Required for the production of the active form of the Aeromonas extracellular serine protease (ASP) (PubMed:11092244, PubMed:12446656, PubMed:25784551).  Acts as a chaperone that helps ASP form an active structure in the periplasm (PubMed:12446656, PubMed:25784551).  Formation of a complex with ASP in the periplasm also inactivates the protease activity and likely protects ASP from intrinsic proteases (PubMed:25784551).  Dissociation of the ASP-ORF2 complex after secretion in the extracellular space generates an active ASP (PubMed:25784551).
What are the official names of this protein?
ASP external chaperone, ORF2.
Protein: TDT_EULMA
Sequence: MDPLQTAHAGPRKKRPRQTGASMASTPQDVRFQDLVLFILEKKMGSTRRTFLTELARRKGFRVENEFSDSVTHIVAENNSGSDVLEWLQVQKIKASSQLEVLDVSWLIECMRTGKPVETTGKHQLVARSDCSASPNPGPQKTPPLAVQKISQYACQRRTTLNNCNHVFTDAFEILAENYEFKENEGCAVTFLRAASVLKSLPFTIITMRDTEGIPCLEDKVKCIIEEIIEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKIRSDKSLTFTRMQRAGFHYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKIGHDVDFLITSPGSTEEEEEQLLHKVMNLWEKKGLLLYCDLVESTFEKLKLPSRKVDALDHFQKCFLILKLHHQRVVDSQKSSQQDGKTWKAIRVDLVMCPYERRAFALLGWTGSRQFERDLRRYATHERRMMLDNHGLWDKTKRIFLKAESEEEIFAHLGLDYIEPSERNA
What is the function of this protein?
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.  One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
What are the official names of this protein?
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_THEP3
Sequence: MDYNKTLNLPRTDFPMKANLPTREPEILKRWEEMDIYHKTLEKNKGKEKYILHDGPPYANGDIHIGTAMNKVLKDIIVKYKTMRGYDAPYVPGWDTHGLPIEQQAIKTLGIKRHEVSPTEFRKVCRDFAFSQIEKQKAQFKRLGVRGDWDNPYLTLNPEYEAKQIEVFGEMAKKGYIYKGLKPVYWCPSCETALAEAEIEYFDETSDSIYVKFRVKDDLGKFKGIVENLNNVYFVIWTTTTWTIPANLAIALNPEFDYALAKFGDEVYIMAKDMLDTVKKEANLSDYEIVAVFKGKDLEGMKATHPLYDRDSLIILGEHVTLEAGTGCVHTAPGHGEEDFLVGQEYGLEVLNPIDDKGYFTDKAPGYAGLYYEEANKVIKEDLKKANALVAETRITHSYPHCWRCKSPIIFRATEQWFASVEGFREEALKAIKEVNWYPSWGEERITNMVRDRRDWCISRQRVWGVPIPIFYCEKCGKPLINDDTINAVKKIFRQKGSDAWFEMSAEEILPKGITCECGSTKFRKETDIMDVWFDSGSSHAAVLQTHPDLKWPAELYLEGSDQHRGWFQSSLLTSVATRGKAPYRNVLTHGFVVDGEGRKMSKSLGNGIDPADVIKEYGADILRLWTVSADFTSDMRISQEILKQMTEAYRKIRNTSKFLLSNLYDFDPDKDMLPYEELLEIDKWALFRLNRVVEELTEAFDKYEYYDFLHLVHTFCVVDMSSLYLDILKDRLYTYPATSKERRAAQTTLYIILDTLVRLIAPVLTFTSEEIWSYMKHDSQNNFESVQLADWPQVQEKYNNPYIIEKWEKLFDIRKDISKALEIARTDKKIGHSLEAQVDIYPSQELYDFFKGFNDLEYVFIVSKVVLHQPEEPAPQNAYESDDYNLKIVVTHAPGEKCERCWMYSETVGTIKEHPTICARCASHIEQQTQV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_ENT38
Sequence: MTDRDTLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNVHHQGCKIIAVDNSPAMVERCRRHLDAYKAPTPVDVIEGDIRTIEIKNASMVVLNFTLQFLEPDNRQLLLDKIYQGLNPGGALVLSEKFSFEDASVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVEAHKARLHKAGFEHSELWFQCFNFGSLVALKGGQA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RL3_LEPCP
Sequence: MTTPNPGQRLGLLGRKVGMMRIFTDDGDAVPVTVLDVSNNRVAQIKTVETDGYSAVQVAFGARKASRVTKPEAGHLAKAGVESGELLQEFRVSAEVAAECKPGSQLPIAMFQAGQQVDVQGTTIGKGFAGTIKRHHFGSQRASHGNSRSHNVPGSISMAQDPGRVFPGKKMSGHLGDDTVTTQNLDVVRVDEARQLLLVKGAVPGAKGGFVTVRPAVKVKLKKGAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ANXB9_DROME
Sequence: MSSAEYYPFKCTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKEDAETDIGYVLVTLTAW
What are the official names of this protein?
Annexin B9, Annexin IX, Annexin-9.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: YE15_CAEEL
Sequence: MTKIKRQINNFDFRRIKILLKKWNVVIYFVLILICFYFIIPIYFPNNDKMNLWLSSIKYYLTYPIYNESLTKTDAYIINTYYYPKSSSLGENAIGMILLMNRNTQRDMTKYRMKLIASNSSHQSVIVTPKFLEESYSSCPYINMVAMVNTLPNLNKLEIFDGERKMEIPFQMGKTTAPASVIICISPQFVAEQWQLFVAHAHVARKFGGHLHMYVTSIIDTFFDLVQEYERLGYVTIDYWMRLKLANSSVDSVEPNLHSELRNQAGAQSDCLYQYKEAAAFITFFDLDDIFIPRGYDSYFDEFSALYELHPNILTFQYTKRETMVYNKAKIEDINFEELFGHTWFVNEEDYGKVMTKPGNLNSMWIHESWNIPTNRHHVSKSNYIIHMQKPVDPDGTDPVSYRMSNFEMLESMQLNASTLIPIQDDLERVLKSSNISMTAEDLPNKTYYFPIIYRCYYEKFYKKPKKDSCPNGEGCLIPQRTGTNCIHSDADFKSGPEMWPITYHYHVNSKWSRTKGCHA
What are the official names of this protein?
Glycosyltransferase family 92 protein C35A5.5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSD_BURPS
Sequence: MNYPHPIIAREGWPFIAIAAVVALLIHAVGGFGLAWPFWLLLVFVVQFFRDPPRAIPTQANAVLCPADGRIVAVETAHDPYADREALKISVFMNVFNVHSQRSPVDGAVQKVEYFPGAFLNAALDKASAENERNAVVIQTGAGHTVTAVQIAGLVARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPKGSRARVSIGEKVSASSTILAELPEQP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1406_HAEIN
Sequence: MKRNWDLIRSILLKLESQSEARGSLLPDGFTGFDSETVSYHFKLLQSAGLIEAIDYSSLNEMSLIARLLTWQGHELLDKIRNDTVWNSLKTTIKSKSLDLSLDAIKQVAQTIISQMLA
What are the official names of this protein?
Uncharacterized protein HI_1406.
Protein: DHAA_MYCTO
Sequence: MTAFGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDALDLGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGRIRDYVRSWPNQTEITVPGVHFVQEDSPEEIGAAIAQFVRRLRSAAGV
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase 3.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: Y1236_ARCFU
Sequence: MAVEAEQCLFLGLDSVVDLHVSHVKNRLARFVGHSSVLCPSCHRHGYVSSCKGNSSLYWNGDPILLAVGDYCNMNFERVNLCIAILLRGCGLHVVNCSNNLSTSCLDLRSLILSSDLLHDLTYWNWLNRCREDVNLPISVVPGVAGLEVVEEVPLAVIATFRVRNRELPPLLLG
What are the official names of this protein?
Uncharacterized protein AF_1236.
Protein: DNLI_SACS2
Sequence: MEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKTIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKTIGDLGEVARRLKSKQQSTGILGFLGTTSKESLTVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIIERAYNLRADLGNIAKIIVEKGIEALKTLKPQVGIPIRPMLAERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQYPDVVDYVSKYIEGKEFIIEGEIVAIDPESGEMRPFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRDYQSEMADTVDLVVVGGFYGKGKRGGKISSLLMAAYNPKTDSFESVCKVASGFSDEQLDELQKKLMEIKRDVKHPRVNSKMEPDIWVEPVYVAEIIGSEITISPLHTCCQDVVEKDAGLSIRFPRFIRWRDDKSPEDATTTDEILEMYNKQPKKKIESPAVDESV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Interaction with PCNA enhances ligase activity.  DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: FTSK_AGRFC
Sequence: MGRMHSPTFDGRHTRFVLTAFFVRQIMALAGFALLATIALGIAALATWNVADPSLSYATGNQPTNLLGYSGAIFADIVMQFLGLSAIIAFLPIIAWAIALIAGRKFNRIPARLVAWVAGAIVCAASLGCFPAPVTWPLPNGIGGVIGDMILRFPALFIGAYPTGTIATILGVIFAAPAAWLMLFAAGIVGGLDDELEREEAVPVATSKARAAREAEEDDEDDGEGFFANMLAFGAIAHYWYITQARLRRLFGLKSKSLHTEFEHPYDFNEYEFGTLNEPSRLKTAINRLDQRSEPSFEERAASRRQMSPPSIALDHDNNADDEPPFDADGRRLPNGILSDDESDDKFTPRQAPGRGQPRITAPSARPKPSERVAREAQASFIAADGFQLPTVHLLAEPKNVVRDNTLSEEVLEQNARLLEGVLEDFGVKGEIIHVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVVPGRNAIGIELPNQTRETVFLRELVGSRDFENSKAKLAMALGKTIGGEPVIADLAKMPHLLVAGTTGSGKSVAINTMILSLIYRMSPEQCRLIMIDPKMLELSIYDGIPHLLSPVVTDPKKAVVALKWTVREMEERYKKMSKIGVRNIDGFNSRVQQALDKGEILTRTVQTGFDRQTGEAMYETEEFDLKPLPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDNEVEEIVAYLKTQGSPEYLEAITEEEDEDGAGSGPAGAGNFSDSEDPYDQAVAVVLRDGKASTSYVQRRLGIGYNRAASLIERMEQEGIIGPANHAGKREILVPTEADIIER
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: PSMG2_XENTR
Sequence: MFVPIGSEQDFPSDYTLLLPAISVGNVGQLAIDLIISTLKIPKVGYFYTDCLVPMVGSNPYETDEENAKELCTNAEVYALPSQKLAVLQLRSLVIKKKSKSFRQALVSWIKRCAFARVILLSSCHAYHRDDTQLFGTPFRYLVTPALQKSVADVLKELEWKEMEKVSSYPGLNDNEKRVFIPGGGFTKRFYDDCCLEDLQMAVVLKFCSEGDNVPDAFSLLNQVNEWLHLVASTNGDVLAKWKAPGSWQLLFGSGLPAAIF
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg1.
What are the official names of this protein?
Proteasome assembly chaperone 2.
What is the protein family that this protein belongs to?
Belongs to the PSMG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_FRATH
Sequence: MANSKQAKKRIIQAERNRQHNVARRSMMRTFLKKTAYAIEKGDVEAAKENFTKVVPILDKYASKGLIHKNKAARHKSRLSAKIKALATAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: GLPK2_MACFA
Sequence: MADPKTAAVGPLVGAVVQGTDSTRFLVFSSKTAELLSHHKVELTQEFPKEGWVEQDPKEILQSVYECIARTCEKLDEMNIDISNIKAVGISNQRETTVIWDKLTGEPLYNAVVWLDLRTQTTVEDLSKKIPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNVRHVQKAVEEGRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLLPNVFSSSEIYGLIKTGALEGVPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTIAYKLGKEKPAYYALEGSVAIAGAVIRWLRDNLGIIETSGDIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDCGIPLRHLQVDGGMTNNKVLMQLQADILHIPVIKPFMPETTALGAAMAAGAAEGVSVWSLEPQALSVLRMERFEPQIQATESEIRYATWKKAVMKSMGWVTSQSPESGDPSIFSSMPLGFFIVSSMVMLIGARYISGMP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Essential for male fertility and sperm mitochondrial sheath formation (By similarity).  Required for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during spermatogenesis (By similarity).  Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria (By similarity).
What are the official names of this protein?
Glycerol kinase 2, GK 2, Glycerokinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerol kinase, testis specific 2.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein. Cytoplasm. Note=In sperm the majority of the enzyme is bound to mitochondria.
Protein: VPB45_MYCTO
Sequence: MQLGRKVTSHHDIDRFGVASTADESVYRPLPPRLRLAQVNLSRRRCRTQSDMYKSRFSECTVQSVDVSVTELRAHLSDWLDRARAGGEVVITERGIPIARLAALDSTDTLERLTAEGVIGKATAQRPVAAGRPRPRPQRPVSDRVSDQRR
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC45 (Potential).
What are the official names of this protein?
Putative antitoxin VapB45.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: IF2_TERTT
Sequence: MAEVTVSELAKSVGASVDRILAQMKQAGLSHQTPDDTVSDEEKQTLLSFLKSSHGESAAAPKKITLKRKTTTTLKTGSGSGRKTVNVEVRKKRTYVKRELTAEDATETAADEVLIPEQEQLESTSVAEIPESVSSDTAVEEIVADTVVEAEVEAASPEPEPEVEATPEPEVEDVVAEEAEPAAAEPAPAPVVEQRSSFVDDAEILRQRAAVRKKAEEEAEVARRKADAEKAEAAAKQKAEQAAVQKGSVEKPAAGDKDESKHHKKPKPKSETEEFDEEAKAKHNKKAGKAVKKVAGPKKVASALDYVEDKEEIDEVIHSAPKSKKGGQNNNSSNSGSRPLIKVANRHGFKKPTGKITYKVEIPEEIVVSELAQRMNVKAGEVVKHLFKLGTMVTINQAIDQETAQLVVEEMGHEAVLVSGDAVEQKLREQVVEVDDAELVARAPVVTVMGHVDHGKTSLLDYIRKTRVASGEAGGITQHIGAYRVNTSHGELAFLDTPGHAAFTAMRARGAQCTDVVILVVAADDGVMPQTEEAVQHARAAGVPLVVAVNKIDKEAADPDRVKNELSAKDVIPEDWGGDTQFINVSAQTGEGIEELLEAVALQAELLELSAPVNVPARGVVIESRMDKGRGVVATVLVQGGELKRGDIMLAGQSFGRVRAMVNEYGDNIDSAPPSTPVEILGLDTPPEAGDEFLVVPDERKAREVSEFRAEKERTERMQRQQAAKLENMFAGMGSDEKKILPIVLKTDVRGSLEAIQAALLDVGNDEVQVNFVGGGVGGITENDVNLALTSGAVIVGFNVRADNSARKLAESESAEIRYYSIIYQLIDEVKSALAGMLDPERVEEIVGIAEVRDVFRSPKFGQVAGCMVVEGNVYRNKPIRVLRDNVVIFEGELESLRRFKDDVNEVRNGMECGIGVKNYDVKVGDQIEVFDVKEVAREL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.