PharMolix/UniProtQA huggingface dataset:
Protein: VM2J_PROJR
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVDDYEVVYPQKVTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYHHGRVHNDADSTASISACDGLKGHFKLQGEMYLIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRHIELAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLSLLDVWSEKDLITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTDINFTGDTIGWAYVGGMCNAKYSVGTVKDHSSNVFVVAVTMTHEIGHNLGMEHDDKDKCKCEACIMAPVISDKQSKLFSDCSKDYYQTFLTNKKPQCILNAPLRTDTVSTPISGNEFLEAGEECDCGSPSNPCCDVGTCKLSPGAQCADGLCCDQCRFKKKGKICRRARGDNPDDRCTGQSADCPRNGLYG
What is the function of this protein?
Inhibits platelet aggregation induced by ADP and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).  Has antitumor-growth activity.
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTA_METEA
Sequence: MNIGVFIPIGNNGWLLSENAPQYMPSFELNKQITLKAEQHGLDFVLSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIKLYATAPTLCLPPAIVARMASTIDSISNGRFGLNLVTGWQRPEYAQMGLWPGDEYFGRRYEYLSEYAQVLRELWETGRSDLKGEFFQMEDCRLSPRPQAEMKIICAGQSTAGMEFTATYADYNFCFGKGVNTPTAFAPTVERLEEAKAKTGRDVSSYVLFMVISDETDEAARAKWEHYKAGADAEAFAWLGLQGAADTKSGADTNIRQMADPTSAVNINMGTLVGSHATVAALLDEVVTVPGTGGVLLVFDDFLKGLDDFGTKIQPLMRSRRHVTGEMLAEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: TM107_RAT
Sequence: MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF
What is the function of this protein?
Plays a role in cilia formation and embryonic patterning.  Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity).  During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins (By similarity).
What are the official names of this protein?
Transmembrane protein 107.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: RIMP_LIMRJ
Sequence: MSSVVETVTDLVTPILQDHDFYLYDLEFVKEGKSWYLRVYINKDGGITLEDCALVSDELSEALDNVEPDPIPQAYFLEVSSPGAERPLKKEEDYQRAIDHYIHISLYQQINGQKVYEGTLTQLSDKEITLDYLDKTRHRQITIDRQKIAQARLAIKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_BURP0
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFTGLLKDFVRANDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMAQGPSA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG2_NEUCR
Sequence: MAAGVDEKDKKTIVFLHPDLGIGGAERLVVDAAVGLQNRGHKVVIFTSHCDPRHCFDEARDGTLDVRVRGNSIIPPSLLGRFSILCAILRQLHLILQITLLTSELRTLSPSAFFVDQLSAGLPLLKLLVPTSPIFFYCHFPDLLLVQGRQTWYKRLYRLPFDTWEEWSMGFADSIAVNSSFTKGIVSHTWPSLASKRSLEVVHPCIDVRSTSDSSQNPNDDDKDVLPWTKTGIILSINRFERKKDIALAIKAFASLSPEQRGKAKLIIAGGYDNRVHENVSYHMDLVDLAEGAPYHLKTATAKTVVSALNTSPDVEVLFLLSVPNTLKEILLRSAKLLVYTPSNEHFGIVPLEAMLRGVPVLAANNGGPTETVVEGETGWLRDPNDVGEWAKVMDKVLNGMGEEELKRMGKKGVERVKGRFADTQMAERLEEIIERMPKGDAAQSGMILLVVGAAVAAVAGVISAVYWKLW
What is the function of this protein?
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
What are the official names of this protein?
Alpha-1,3/1,6-mannosyltransferase alg-2, Asparagine-linked glycosylation protein 2, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RS10_SALTY
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LYSC2_PIG
Sequence: MKTLLVLALLLLSVSVQAKVYDRCEFARILKKSGMDGYRGVSLANWVCLAKWESDFNTKAINHNVGSTDYGIFQINSRYWCNDGKTPKAVNACHISCKVLLDDDLSQDIECAKRVVRDPLGVKAWVAWRAHCQNKDVSQYIRGCKL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C-2, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTND_PROMM
Sequence: MSRLSIHPEGSTNATSPAEPLLESDDPAVIKVELAKRGIAFQRWPAKVKLDQNSSESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLDEHTHAEDEVRFFVEGCGLFCLHIGAEVLQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIANFTGDAIAERFAKLP
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: ASTD_SHIFL
Sequence: MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVEQACRAARAAFPRWARLSLAERQVVVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLASLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQAGTSLLTPGIIEMTGVGGVPDEEVFGPFLRVWRYDTFDEAIRMANNTRFGLFCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: TIGIT_HUMAN
Sequence: MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFFTETG
What is the function of this protein?
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
What are the official names of this protein?
T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL10_METEP
Sequence: MDRTAKADLVSTLNGVFNANAVVVVAHYKGLTVADMQKLRSQMKQAGATVKVAKNRLASIALDGTDVASIKPLLKGPTLLAYSSDPVAAAKVAVDFAKTNDKLVILGGAMGTTALNPDGVKALASLPSLDELRAKLVGLIQAPATKVAQVVNAPAAKLARVFGAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RLMH2_THEPX
Sequence: MKIHIIAVGKIKENYINNGINFYLKKLRPYCEIEIREVEEEKAPQNLSEKEKEEILRKEGERILSKIKKGSFVVSLAIEGKEIDSYKFSQFIKATFQSGYREMTFVIGGSLGLWENIKKQSHLNLSFSKMTFPHQLMRLILLEQLYLAFDGKNHL
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H 2, 23S rRNA (pseudouridine1915-N3)-methyltransferase 2, 23S rRNA m3Psi1915 methyltransferase 2, rRNA (pseudouridine-N3-)-methyltransferase RlmH 2.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRP7
Sequence: MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIVLNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEFIDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKYDDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDIDKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADTLEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQEETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTVALKQLEELSLQVEEDETNKTN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIP_THIPF
Sequence: EDLPHVDAATNPIAQSLHYIEDANASERNPVTKTELPGSEQFCHNCSFIQADSGAWRPCTLYPGYTVSEDGWCLSWAHKTA
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein, HiPIP.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
Protein: RLMN_RHIME
Sequence: MAATEILNRADIVKAPQVRLAPQPEKPSLIGLLRDDIAKLLAEKGVPERQVKMRVSQLWHWLYVRGVSDFDEMSNVSKDMREMLKEHFTIARPDIVEEQVSGDGTRKWLLRFPPRGAGRPVEIETVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTAEEILSQLLLARDRLGDFPERDTPQGAIVPAEGRKITNIVMMGMGEPLYNFENVKTALLIASDGDGLSLSKRRITLSTSGIVPEIYRTGEEIGVMLAISLHAVRDDLRDMLVPINKKYPLKQLMEACRAYPGLSNARRITFEYVMLKDVNDSLEDAKELVKLLKGIPAKINLIPFNPWPGTNYQCSDWEQIEKFADFINQAGYASPIRTPRGRDILAACGQLKSESERMRKVDRLAFEAMMIANHGED
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O261_CONMR
Sequence: MQKLTILLLVAAVLLSTQALNQEKRPKEMINVLSKGKTNAERRKRQCEDVWMPCTSNWECCSLDCEMYCTQIG
What are the official names of this protein?
Conotoxin MaI51.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOB_XANOR
Sequence: MGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGASRLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQKKIWRTQTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAA_LACLA
Sequence: MASLNENQKFWARVTELAQQSIGKQAYDFFIEPAQLMSVEQDTANILLDSGMKKDYWKKQSDLITTAGFEVFGRMIDYELYANDELTELELHRLNNQSSIEEQPRSTAKPASPLVSGLNEKYNFENFVQGPGNRWTLAAAIAVADKPGDTYNPLFIYGGAGLGKTHLMHAIGNQILTDNPTARIKYVSSENFVNDYVNATRKNQMENFENTYRNLDLLLLDDVQFFSDKEGTKNEFFNTFNALYDKGSQIVLTSDRIPQELNNLEDRLVSRFSWGLTTDITAPDYETRMAILLIKSESSRLEFPSETLSYIAGQIDSNVRELEGALNRVEFVARANGIAVVDIETASQALRSLKNATQQSLSNLTIKKIQDEVANYYHISFSDLVGPKRPKEIAFPRQIAMYLVRELLGTSLPAIGTAFGGRDHTTVMYAYKQISDKMKNDMDVQKDIDSIKRKF
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUF3_ARATH
Sequence: MELQTMKITKDCVVEVSSEEEGFEGAWFRAVLEENPGNSSRRKLRVRYSTLLDMDGSSPLIEHIEQRFIRPVPPEENQQKDVVLEEGLLVDADHKDGWWTGVVVKKMEDDNYLVYFDLPPDIIQFERKQLRTHLIWTGGTWIQPEIEESNKSMFSPGTMVEVFSAKEAVWSPAMVVKETDVDDKKKFIVKDCNRYLSCNGDEARPTNIVNSRRVRPIPPPSSVDKYALLESVETFSGLGWHKGQVRKILSENRYTVRLEATQQESTIRHSDLRPFMVWEDGVWYNDLKQKPIKETPPTILKRKPMRSCSAAKSMTPTSATKHLRSFLNSKEISETPTKAKFVSATRELGKNKADAVMNDKTHLLITPQETSIAPVITVTPLKQQDAETEGKKSPKKTPEPVKHQNGLENSSTQHEMPEEENSNEKSRKRKREQNQNSNLNETDETCNVSKAGVNGTSDTIRVDDVDDQPLSSWINIPTVLSSDQSSNVVDNSAADVEETQAKGALTIEPFTKNLPFWKTYEMEKGYKTVPQNPHFSPLLEFKEDIREWSAVGMMVSFYGLLEEVKKLQLDVSSSKLGSLSTCFAELEKHGFDIATPQSRINKVLSLQVGRAKKVEERKCLEKRIEAEEIEMQKFEHEMVEVERKMLELKRRAEVAKEKKEAADKMIVEMKSSAETIDQEIANVELEFITSVLAPW
What is the function of this protein?
May be involved in the polar growth of plant cells via transportation of RNAs.
What are the official names of this protein?
DUF724 domain-containing protein 3, AtDUF3.
Protein: OBG_SHEON
Sequence: MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLEADENFNTLIEYRFERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAIDHDTEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSYVIADIPGLIEGAAEGAGLGIRFLKHLERCRILLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKAERVVKELGWEGEVYTISAYGRDGTKELAAKLWDFIQSLPPEDKDANPEDEVEFKWDNYHQANIDAINEDYDDDFDDDFDDDDYDVEVIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILL2_ARATH
Sequence: MALNKLLSLTFQLLLFLLSVSSESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELELIGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNASVNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHFSLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL
What is the function of this protein?
Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Ala, IAA-Leu, IAA-Met, IAA-Phe, IAA-Ser, IAA-Thr, IAA-Tyr and IAA-Val (PubMed:11923288).  Is the most efficient enzyme of the ILL family for IAA-Ala (PubMed:11923288).  Not important for IAA-Leu hydrolysis in roots (PubMed:15155875).  May act with ILR1 to provide free IAA to germinating seedlings (PubMed:15155875).
What are the official names of this protein?
IAA-amino acid hydrolase ILR1-like 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NS1_I78A4
Sequence: MDSNTVSSFQVDCFLWHVRKQFADQELGDAPVRDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKRAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEGGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: GFT1_ARATH
Sequence: MSSSRFDSNKQLTTSSLVIGYALCSSLLAVINKLAITYFNYPGLLTALQYLTCTVAVYLLGKSGLINHDPFTWDTAKKFLPAAIVFYLAIFTNTNLLRHANVDTFIVFRSLTPLLVAIADTVFRSQPLPSRLTFLSLVVILAGAVGYVATDSSFTLTAYSWALAYLVTITTEMVYIKHMVSNIKLNIWGLVLYNNLLSLMIAPVFWFLTGEFTEVFAALSENRGNLFEPYAFSSVAASCVFGFLISYFGFAARNAISATAFTVTGVVNKFLTVVINVLIWDKHATPVGLVCLLFTICGGVGYQQSVKLDKPIEKVSEKDSEKGEEDEELTQLVPGKLASVV
What is the function of this protein?
Acts as the major nucleotide-sugar transporter for the import of GDP-Fucose into the Golgi lumen.  Transports GDP-Fucose in a strict counter-exchange mode.  Is required for proper plant growth and development (PubMed:27381418).  Acts also as a GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen (PubMed:15480787).
What are the official names of this protein?
GDP-fucose transporter 1, GDP-mannose transporter GONST4, Protein GOLGI NUCLEOTIDE SUGAR TRANSPORTER 4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. GDP-Mannose:GMP antiporter (GMA) (TC 2.A.7.13) subfamily.
Protein: O1312_DANRE
Sequence: MNSTSNSSLGNTFISKTLKEKSLTVQVLVGILLYVNGLMIFTFLKKETFRDTRYILFAQTLFVDSALMLFADLTLVGSAYELFIHIISCYIFCTVMALLSICSPVTLVAMCLERYVAICLPLRHASISSPKNTINGLLIIWGVSSVIPLFIFIVSFTYTPPNAMNSYVVCSNDVMFQVKWLAEMRALSQQLLFVIMLCIVGSTYIKIMVAAKSASAENKKSTYKGLRTVILHGLQLILGMMQLITPYIDILTLKVDIMLFINVKFSNFMLFWIFPRCLSPLVYGLRDKKFYNALKYYAFCGIYVCKKHKIKDSKTIRGAVSIAIY
What is the function of this protein?
Probable olfactory receptor.
What are the official names of this protein?
Odorant receptor 131-2, Odorant receptor family H, subfamily 131, member 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Mainly found at the plasma membrane. Also shows punctate cytoplasmic expression.
Protein: ILEU_BOVIN
Sequence: MEQLSAANTRFAVDLFLTLTEHNPAGNIFISPFSISSALAMVFLGARGDTAAQMSKALHFEGVEIHSGFQSLNADINKCGAPYTLKLANRLFGEKSYDFLPEFLASTQEMYSAELASVDFLRAPEDARKTINAWVKEQTGGKIPELLASGMVDSLTKLVLVNAIYFKGKWQEKFMVEATKDAPFRLNKKETKTVKMMYQKKKFPFGYIKDLKCRVLELPYEGKDLSMVILLPDDIQDEATGLKKIEQQLTLEKLREWTRPESLDLLEVRVQLPRFKLEESYDLQEPLARLGVRDLFSSKADLSGMSGAKDLFISKVVHKSVVDVNEEGTEAAAATGAIAEFAMLVPEEEFVADHPFIFFIRHKPSSNILFLGRLSSP
What is the function of this protein?
Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis.  Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection.  These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality.  Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3.  Acts also as a potent intracellular inhibitor of GZMH by directly blocking its proteolytic activity.  During inflammation, limits the activity of inflammatory caspases CASP1, CASP4 and CASP5 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation.  When secreted, promotes the proliferation of beta-cells via its protease inhibitory function.
What are the official names of this protein?
Leukocyte elastase inhibitor, LEI, Serpin B1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytolytic granule. Early endosome.