PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_CLOP1
Sequence: MKLTPMMRQYFEIKENYKDCILFFRLGDFYEMFFEDAETAARELELVLTGRDCGLEKRAPMCGIPFHASNSYIGRLVAKGYKVAICEQVEDPKFAKGIVKRDVIKVITPGTYTDSSFVEETKNNYIMTIYADLERNRCSLAITDISTGDFLATEGELEKGVILDEISKFNPKEIILLDSLDQELIKDITLTTPALISRKPIEYFEENFEEVLNNQFGEKSNSLSLMVKKSSNALVKYILDTQKISLTNINDIEVYSLVDFMTIDLSSRRNLELTENLREKSKKGSLLWVLDKTETSMGSRMLRRWIEEPLVNKEKITLRLNAVEELFNDLSLNDSLKEALHDIYDIERILGKISNKNANAKDLIALKTSIGKIPNVKGIIENCTSSLLKNYHHNLDDLRDIYDLLEKSIKEDPSLTLKDGDLIKDGFNGEIDELRLAKTNGKDWISSLENREREFTGIKSLKVGFNKVFGYYIEISKANYSSIPEGRYIRKQTLANAERFITPELKEIEEKLLGASEKLCSLEYDIFLDIRNEVENHIDRLKTTAKIIAELDCISNLAFVALENDFIKPEINEDGETKIENGRHPVVEKVIPKGEFIPNDTIINKDDNQLLIITGPNMAGKSTYMRQVAIITLMCQIGSFVPASKANISVVDKIFTRIGASDDLAGGKSTFMVEMWEVSNILKNATENSLVLLDEVGRGTSTYDGLSIAWSVIEYICKNKNLRCKTLFATHYHELTKLEGEIHGVRNYSVAVKEVDNNIIFLRKIIEGGADQSYGIEVAKLAGIPDEVINRAKEILETLEMESSKDNLDLALKEVNASKEDIEEASITTSYEVKETLVEEDKIEIKEEVISKASEAKTHKKEDDQIQLDFSAIGKDNLIKELSEVDILSLNPMEAMNRLYALVKEAKNLI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RNI_ECOLI
Sequence: MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQTGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFGCATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACFGFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKLTCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY
What is the function of this protein?
One of the few RNases that cleaves the phosphodiester bond between any two nucleotide.  Shows a preference for cytidylic or guanylic acid.
What are the official names of this protein?
Ribonuclease I, RNase I, Enterobacter ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Periplasm. Cytoplasm. Note=RNase I (periplasmic) and RNase I* (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA.
Protein: ALR_LIMRD
Sequence: MVNGRLRDTSLIVDLDALRHNIQEQKKVLPENSKILAVVKANAYGNGLIPVAQTAMTSGASGLCVAILDEALELRDNGIEAMTLVLGITSVEDALIAAQAGVSLTVGSLDWLEQYHQLAQVAKPKKPLKVHLGIDSGMGRIGFTEVAAFKQAVKLLDSPEFEFEGMFTHFATADSPDENYFNQQVQRWHQFVASLAELPPYVHMANSATGLWHRETITANTIRMGISMYGQNPSGRDLKLTLDLQPVSSLVSSISFVKQLKAGRSVSYGATYTAEQDEWLATLPIGYADGYPRCMTGYKVLVDGQFCDIAGRVCMDQMMIRLPKYYPVGTPVVLMGKSGDQEITATDLAERAGTINYEILTNISNRVHRIYRQSK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ROSY1_ARATH
Sequence: MAISHTQLLLLLLVSLFFSPALCGPKFQTCDTGKEYPLKVSSVEISPDPVKRSGNGEITITGVTNKEISDGVTVNLKLAVGMFPVSTKSYSLCDITACPVAPGPIVLTLPNIFTPREKRTAIGYTIIISITDKPLKESMMCILFVVKLTGHASMINQVTE
What is the function of this protein?
Involved in the regulation of gravitropic response and basipetal auxin transport in roots.  Involved in salt stress tolerance.  May facilitate membrane trafficking and asymmetric cell elongation via SYT1.  Binds stigmasterol and dipalmitoyl phosphoethanolamine (DPPE) in vitro.
What are the official names of this protein?
MD-2-related lipid-recognition protein ROSY1, Protein INTERACTOR OF SYNAPTOTAGMIN 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDKL3_RAT
Sequence: MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTTYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLHNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPAERISSTDLLHHDYFTRDGFIEKFIPELRAKLLQEAKVNSFIKPKENFKENEPVRDEKKPVFTNPLLYGNPTLYGKEVDRDKRAKELKVRVIKAKGGKGDVPDLKKTESEGEHRQQGTAEDTHPTSLDRKPSVSELTNPVHPSANSDTVKEDPHSGGCMIMPPINLTSSNLLAANPSSNLSHPNSRLTERTKKRRTSSQTIGQTLSNSRQEDTGPTQVQTEKGAFNERTGQNDQIASGNKRKLNFSKCDRKEFHFPELPFTIQAKEMKGMEVKQIKVLKRESKKTDSPKIPTLLSMDSNQEKQEVFNIFPGWCKRGNLNWPS
What are the official names of this protein?
Cyclin-dependent kinase-like 3, Serine/threonine protein kinase NKIATRE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
[Isoform 2]: Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm.
Protein: ATPB_DESDA
Sequence: MSKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRTIAMDATEGLVRGMDAVDTGQPIMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPAPAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGVGKTVILMEMINNIAKQHGGSSVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITSVQAVYVPADDLTDPAPATTFSHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEEHYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVARARRIQRFLSQPFHVAETFTGTPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BGLR_MOUSE
Sequence: MSLKWSACWVALGQLLCSCALALKGGMLFPKESPSRELKALDGLWHFRADLSNNRLQGFEQQWYRQPLRESGPVLDMPVPSSFNDITQEAALRDFIGWVWYEREAILPRRWTQDTDMRVVLRINSAHYYAVVWVNGIHVVEHEGGHLPFEADISKLVQSGPLTTCRITIAINNTLTPHTLPPGTIVYKTDTSMYPKGYFVQDTSFDFFNYAGLHRSVVLYTTPTTYIDDITVITNVEQDIGLVTYWISVQGSEHFQLEVQLLDEGGKVVAHGTGNQGQLQVPSANLWWPYLMHEHPAYMYSLEVKVTTTESVTDYYTLPIGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGKGFDWPLLVKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNESLRHHLEVMEELVRRDKNHPAVVMWSVANEPSSALKPAAYYFKTLITHTKALDLTRPVTFVSNAKYDADLGAPYVDVICVNSYFSWYHDYGHLEVIQPQLNSQFENWYKTHQKPIIQSEYGADAIPGIHEDPPRMFSEEYQKAVLENYHSVLDQKRKEYVVGELIWNFADFMTNQSPLRVIGNKKGIFTRQRQPKTSAFILRERYWRIANETGGHGSGPRTQCFGSRPFTF
What is the function of this protein?
Plays an important role in the degradation of dermatan and keratan sulfates.
What are the official names of this protein?
Beta-glucuronidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
What are the subcellular locations of this protein?
Lysosome. Endoplasmic reticulum. Note=A small proportion is found in the endoplasmic reticulum.
Protein: TLR1_MOUSE
Sequence: MTKPNSLIFYCIIVLGLTLMKIQLSEECELIIKRPNANLTRVPKDLPLQTTTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNELKVILCHPTVSLKHLDLSFNAFDALPICKEFGNMSQLQFLGLSGSRVQSSSVQLIAHLNISKVLLVLGDAYGEKEDPESLRHVSTETLHIVFPSKREFRFLLDVSVSTTIGLELSNIKCVLEDQGCSYFLRALSKLGKNLKLSNLTLNNVETTWNSFINILQIVWHTPVKYFSISNVKLQGQLAFRMFNYSDTSLKALSIHQVVTDVFSFPQSYIYSIFANMNIQNFTMSGTHMVHMLCPSQVSPFLHVDFTDNLLTDMVFKDCRNLVRLKTLSLQKNQLKNLENIILTSAKMTSLQKLDISQNSLRYSDGGIPCAWTQSLLVLNLSSNMLTGSVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRSLTAGNNPFQCTCELRDFVKNIGWVAREVVEGWPDSYRCDYPESSRGTALRDFHMSPLSCDTVLLTVTIGATMLVLAVTGAFLCLYFDLPWYVRMLCQWTQTRHRARHIPLEELQRNLQFHAFVSYSGHDSAWVKNELLPNLEKDDIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLAPIPQYSIPTNYHKLKTLMSRRTYLEWPTEKNKHGLFWANLRASINVKLVNQAEGTCYTQQ
What is the function of this protein?
Participates in the innate immune response to microbial agents.  Specifically recognizes diacylated and triacylated lipopeptides.  Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  Acts as a coreceptor for M. tuberculosis lipoproteins LprG, LpqH and PhoS1 (pstS1), in conjunction with TLR2 and for some but not all lipoproteins CD14 and/or CD36.  The lipoproteins act as agonists to modulate antigen presenting cell functions in response to the pathogen (PubMed:19362712).
What are the official names of this protein?
Toll-like receptor 1, Toll/interleukin-1 receptor-like protein, TIL.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Golgi apparatus. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to triacylated lipoproteins, TLR2:TLR1 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus.
Protein: MUTS2_BACC2
Sequence: MLERTLRVLEYNKVKEQLLEHTASSLGRDKVKHLVPSTDFEEIVEMQDTTDEAAKVIRLKGSAPLGGITDIRSNVKRAKIGSMLSPNELLDIANTMYGSRNMKRFIEDMVDNGVELPILETHVAQIVSLYDLEKKITNCIGDGGEVVDSASDKLRGIRTQIRTAESRIREKLENMTRSSNAQKMLSDSIVTIRNERYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEIERILLMLTEEVAVEADIVLSNVEVVANLDFIFAKAFYAKRIKATKPIVNNERYMDLRQARHPLIDPEIIVPNNIMLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVMDESEICVFKNIFADIGDEQSIEQSLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVCNRGARVVATTHYPELKAYGYNREQVINASVEFDVNTLSPTYKLLIGVPGRSNAFEISKRLGLSDRVIDQARNHISTDTNKIENMIAKLEESQKNAERDWNEAEALRKQSEKLHRELQRQIIEFNDERDEKLLKAQKEGEEKVEAAKKEAEGIIQELRQLRKAQLVNVKDHELIEAKSRLEGTAPELVKKQKVNVKNTAPKQQLRAGDEVKVLTFGQKGQLLEKVSDTEWSVQIGILKMKVKESNMEYINTPKQTEKKAVASVKGRDYHVSLELDLRGERYEDAMMRVEKYLDDAQLASYPRVSIIHGKGTGALRQGVQDYLKKHRGVKNYRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: SOHB_SHIFL
Sequence: MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRVNNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPRVWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQRLRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVATGEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESADRLLLRWWQRGQKPLM
What is the function of this protein?
Multicopy suppressor of the HtrA (DegP) null phenotype.  It is possibly a protease, not essential for bacterial viability (By similarity).
What are the official names of this protein?
Probable protease SohB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: LIP1_YARLI
Sequence: MSVTSTSLNGTFNGISEDGIEIFKGIKYANIPYRWAYAERIDDYDNGVFDCTQEGMACPQVLPFDYNIEKGPKEMPFDEFECSNLMITRPQGATNLPVFVWIHGGGNLAGNGYCSDHNPVPFVKHSIVAGRPVLHVMIEYRLSAFGYLAVPDTNGNWVGNWGARDQYTALQWISKHIVEFGGDPSQITIGGESAGSIGLHALMVHESMKPKEECIIHNVILSSGTMDRMGTGTISENAFKPIYDGIKTLVGDINTCSADELLEAQIKAGLDLGFYLQDDFFPPDWRNVRFKVSRVLLSDVIVDGTNFKNKINPAVRVTPENDFDHKVFKLYNISTEDTWEDYHYKMMLFKGDETFIRGNQQLELLFEQENIPVWRQLFDQIHPNDPSRLCHHAVDLYYMWDNWEMPEDKHAVARQYQDTLTKFVYGQDPWPVDKLHYVHDNQFEILDKSQFGDFRNVPALKFLLGFSAEELGELTKKYTGEGHYTL
What are the official names of this protein?
Lipase 1.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: PAN1_CANAL
Sequence: MYNPYQQQQQGMGYNPQQQTGYGYNNYQMPQQPQFNQQPMYPQATGFVPQQPNLYGSNFQTSGGSGMAPQQTGFSQQQTMQPQQTGYIQTQPTGFGGTAPIVTENSELKIPSIRLSFISAEDQKKFEHLFRTAVPKGEQSISGDSASGILLRSGLSAVTLAEIWNLSDIDKTGSLLFPEFALSLHLCSMAKRGEPLPGILPEKWLNEVRSFVDQINFTVPDDPSKILANTPFANFAPKKESDWLAPQSTGYLQNQSAPPMTSFQPQVTGFGGQGLVSQATGGVPMPSTTFGNAAGLTAQRTGGGTLIPLQPQQTAGLIPAQKTGPLNPQTTGFNQQSLQQQRTGGLPQQLTGYQGPPQGQGQQLQQQRTGGFPQVQSQPTGGFVPQTSFQQPQLVSQRTGPMQAQPTGSLQAQPTGRPGEWGFVSMPTGGIPGLNAMQQHFLPNNQLPTSNLHSAMDNKLKENVTWAITKQEKQIYDGLFQAWDNQKKGYVDSNVALNVFTKSGLSRSDLESIWTLVDTDDTGKLNKNQFAVAMHLIYRRLNGYDIPLRLPPELIPPADRTLKDTMDSLKNSLKGGVNNKPTKPPKPQSKPDGTRFKNDDNNFGYVSNVRHRRKSTSDESHKSSVKSSSDYDLSIEDMKKLIHEKRILLDALDTEDQANNYSRSSSSMHEKQIIENLKKEIMAVQTKLDERGNDGPSSDERNKLLATLDHLTRDVVPRLISDIHKVNQEISRKKAEVFKLELLKKNPSWNPEDDESQIQGTGPNGEVTDYDRIKYQSRQKLKQRMAALTGKSTGGNSDLDLELKQATEKAQDEASRQSEMIQDIAAGIKTMEDECAAKLSSSVTEDVGHEKWEQGKGISSEVAKFVKELEAFSKEQRRNIAKSQKQEQTREPLAKQQTNASLVSDSGAAKSAYATPEERAAYIKQQAEKRMNERLAKLGITRKSKSTEQKPPVESKSVSNHSPVPDSEVKSVTRNANEVEVQKPKPDSQPVSKNREPAEQPNSKADTNSVGSQNVVSNTNDDTSGDDDDEEYKAILKQKQEMEARERERKLRKQKAKEERLAKIKKEMEEMKKREMEESQDEEEEEAKQVTSVHVSRAQSSNANSNVIPQQETATENVNTVSQPTSTDTAKQSYHPHESNPFSKMNNNTSQNSTVTNTGTNPFFKSTSQETKIDPHKAEAQRASQRGVASSGGWSDSEEEESEEESPNRAGAAKLASLLFGGMPQPPTTSSSSLNNDAEKVSEQEHENAKQVASTPLSNDDNGKTDSGPSGFAGENESSFSQAPPIPVDAPPAPNSIPPPPPPPPQFSNEAPPVPDSIPPPPPPPSVPSTVPALPDSMPPPPPPPPPPAAPNNTSSSQQASGAPNIGALLGQITGGASLRKVETKVSSGATVGRVL
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein PAN1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Localizes at sites of polarized growth like the hyphal tip.
Protein: GLGB_MYCUA
Sequence: MSRTDQLAGTHLAPEPNDLALLVAGSHHNPHGVLGAHEYGDHIVIRAFRPHAAEVIAIVGDDRFPMQHIESGLFAVALPFVDLIDYRLQVSYENSEPFTVADAYRFLPTLGEVDLHLFAEGRHERLWEALGAHPRSFTTADGVVHGVSFAVWAPNAEGVSLIGDFNGWSGSEAPMRVLGSSGVWELFWPDFPADGLYKFRVHGADGVVSERADPFAFGTEVPPQTASRVTVSDYSWGDGDWMTERAQRNPVFEPMSTYEVHLGSWRPGLSYRQLATELTDYVVAHKFTHVELLPVAEHPFAGSWGYQVTSYYAPTSRFGTPDDFRALVDALHQAGIGVIVDWVPAHFPKDAWALGRFDGTPLYEHSDPKRGEQLDWGTYVFDFGRPEVRNFLVANALYWIEQFHIDGLRVDAVASMLYLDYSRPQDGWTPNIYEGRENLEAVQFLQEMNATAHKAAPGIVTIAEESTSWPGVTRPTSIGGLGFSMKWNMGWMHDTLDYVSRDPIYRSYHHHEMTFSMLYAFSENYVLPLSHDEVVHGKGTLWGRMPGSNHTKAAGLRSLLAYQWAHPGKQLLFMGQEFGQRAEWSEQRGLDWFQLDENGFSNGVLRLVRDINEIYCDHCALWSQDTTPEGYSWIDANDSANNVLSFLRHGSDGSVMACIFNFAGSEHSDYRLGLPIAGRWREVLNTDATIYNGSGVGNFGGVDATAEPWHGRPASAVLVLPPSSALWLEPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: GCY12_CAEEL
Sequence: MWPTSVEALRFYHTFAFSPGRRRRLFGLSIVFVIAALCVTSCDADAVPAPSPEAEPSLGAGANPYLLDSLVKRLPKKGDKKEILISYLAAVPTLMGEIDQYLLNLSASNSAQNSSKDRESFSKKLNQIVHCLTTDAYVSVVSGALVAAIVEINQDKDLIPAYQLKYVFGNTCGNDSHSTRLFMEHWQAGARVFIGPEKNCKTEAAMAASQNLPIISYRCNDQDISRDDYHYRTFARTVPPAGEIFKAFMSLMKQYNWRKFSVVYDVKKGQVKNELFETLKRMVETENKFEEHKFEIMNVSKLEFSKMDISSQQDIQSIENAIKSTMQTTRIYLTFDNVRLFRTMLSIMGEMGLTQQDYMLIYVDTNYDWLNVYHSMNNHFLRNTMTYLHHSWDANNSSDRKMLDYARSALSIIPTPVKLNSQRFYNFWKKAGDYMHHFGVQKADNLKGNRIACYLYDAVYLYAKAIHELVEEYGNDDSYDPTADGKAIIDRIVNKKYRSIQGFDMRIDERGNSKGNFSLLSWQKVAPIMNKSDPSYYPLDHALDLTAIFVEAPDKDRLPNLQFKSSRIQWLKGEPPPDEPVCGFHGENCRKKGIFSYLTVVVMILIAVFSLVLTGFTLNYIRSRRFEKELSMIWKIDPYEVRRVVGGVNNESTASLMQSDVMQFAKTKTPWWSKAPVQGTGMRGLASYKGTLVGLKDLMYGRKPKDLTREAKKELRAMRQLAHPNVNNFLGIIVCQYSVTVVREYCSKGSLHDILRNENLKLDHMYVASFVDDLVKGMVYIHDSELKMHGNLKSTNCLITSRWTLQIADFGLRELREGIMYDSSYNIWENFLWTAPEAMTINGSLAISNPPTPKADAYSFGIIFHEIFTREGPYKIYVQRGDVNGEAAPKKDSVECRALVEKTVRRVYSDPYFRPDTSDLEVQNYVKEVMAACWHHDPYQRPEFKTIKNKLKPLFHQIYKQNIMDHMVLMMEKYQTQLEDLVDERTIELKDEQRRSQHLLQRMLPSSVAEQLLAGQDVIPEAFPPVTIYFSDIVGFTTISGESTPMEVVTFLNKLYTLFDSIIRRYDVYKVETIGDAYMVVSGVPQYKTMEYHAEQIAMMAIHILSAVRSFSIPHRSCEPLMIRIGMHTGPCVAGVVGKTMPRYTLFGDTVNTASRMESNGEALRIHCSSSTQKVLTSIDQGFLLEERGSLAIKGKGQMTTYWLNGRAGYEFTETIEDKMVVPDIFPRPNLKNRGSSWGVNRESSLSLATEKSSQIMKRQSAAMNRNNQDVIYYNQPLNSGGFTSRGTSNREMPKLYEEDRESLLNQSASLLGSRTSGRKKSTASKYNGFSASRMFSSTISNASSSRPSRPSTFDHDTLALRKRSTSLPDGEKLNLEFIETTNLANNSVPAIPNNISSLEPVFRKASIIDGYSSQSESPSQSQYPSYRDLTTGPHQRKRGIATVFPVRKRSLSCGDAVPLKINENGASGSITTAVSPRSSCRALDPTMKLAARASSPDEIIFQEDDEDALIDNDSLLTSNGNSKSEDVLRTCPQPRRKNKHSFLRDPSPLAKRFRDASPFGKKKPFWNSNKSNEHTSSPADSISRLFRRFRGGSVNEYADLNHYCDDEDESGRANGYEMQEMGKMTGRQREQRNGSRTNRSVSCSPDECGTLTDSSDPHLTIPSSSIGDSSASTSLSCS
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (PubMed:9096403).  Acts upstream of cGMP-dependent protein kinase egl-4, most likely by providing cGMP to the kinase in chemosensory neurons to regulate body size (PubMed:21124861, PubMed:26434723).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-12.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Perikaryon. Cell projection, dendrite. Note=Localization in cilium of sensory neurons is regulated by daf-25 (PubMed:21124861). Cilia localization may be important for regulating body size (PubMed:21124861). Localizes to small puncta around the nucleus in the perikaryon (PubMed:26434723). Enriched at the proximal segment of the cilia or at the distal dendrite tip close to the cilia (PubMed:26434723).
Protein: IF1_PELUB
Sequence: MSKQEMLSFSGIVEDLLPNAMFRVKLENGHIVTAHAAGKLRKNRIRVLQGDKVQVEMTPYDLTKGRITFRG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_STAEQ
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYEEISEGDEVKRTGRIMEVPVGEEMIGRVVNPLGQPIDGQGPINATKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAIDSILNQKDQDTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVSASAADPAPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTAKKLARGERTVEVLKQGQNNPLPVEHQVLIIFALTKGYLDDIPVQDINRFEEEFNHWAESNATELLNEIRETGALPDADKFDSAITEFKKGFNKSEE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NIP31_MAIZE
Sequence: MEPGSTPPNGSAPATPGTPAPLFSSGGPRVDSLSYERKSMPRCKCLPLPAVEGWGVATHTCVVEIPAPDVSLTRKLGAEFVGTFILIFFATAAPIVNQKYGGAISPFGNAACAGLAVATVILSTGHISGAHLNPSLTIAFAALRHFPWLQVPAYVAVQALASVCAAFALKGVFHPFLSGGVTVPDATVSTAQAFFTEFIISFNLLFVVTAVATDTRAVGELAGIAVGAAVTLNILVAGPTTGGSMNPVRTLGPAVAAGNYRQLWIYLLAPTLGALAGASVYKAVKLRDENGETPRTQRSFRR
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin NIP3-1, NOD26-like intrinsic protein 3-1, ZmNIP3-1, ZmNIP3;1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL11_SYNWW
Sequence: MARKVLGKISLQIAAGKATPAPPVGPALGQYGVNIMGFCKEYNARTANQAGYIVPVEITVFEDRSFTFVIKSPPASDLLKKAANIDKGSGEPNKKKIGKVPRAKLLEIAETKKEDLNASDIEAAVKMIEGTARSMGLEIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL34_SINMW
Sequence: MKRTYQPSKLVRKRRHGFRARMSTKGGRKVLTARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ACCD_RHIE6
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLESNKWVIPASGYHMKMPAKARLADLFDNGEYESLPQPKVAQDPLKFRDSKKYIDRLRDSRVKTEQEDTILAGLGKVRGLKLVAVVHEFNFIGGSLGIAAGEAIVKAFERATLEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDLLKESGQPYVVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGKRVIEQTLREKLPEGFQTSEYLLEHGMVDMVVKRHDIPETLARLLKILTKKPVSAANDMNGGAIALAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_SPOFR
Sequence: MAIRPVYRPTIVKKRTKRFIRHQSDRYDKLKRNWRKPRGIDNRVRRRFKGQYLMPNIGYGSNKKTRHMLPNGFRKVLVHNVRELEILMMQNRKYCAEIAHGVSSKKRKTIVERAQQLSIRVTNSAARLRSQENE
What are the official names of this protein?
60S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: MSRA2_STAAM
Sequence: MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYEQVCTNKTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYHDEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQRGSGRKAFIESHWGNQNA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA 2, Protein-methionine-S-oxide reductase 2, Peptide-methionine (S)-S-oxide reductase 2, Peptide Met(O) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.