PharMolix/UniProtQA huggingface dataset:
Protein: RL9_ERWT9
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEFFETRRAELEAKVADVLAAAHARAEKINALGTVTLASKSGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVDFQVHSEVFAKLTVNIVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PPAC_STAA2
Sequence: MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB2_RAT
Sequence: MAAALQRIEQLSSRVVRVLGCNPGPMTLQGTNTYLVGTGSRRILIDTGEPSVPEYISCLKQALAEFDTAIQEILVTHWHRDHSGGIVDICKNISNDATYCIKKLRRNPQKEEIIGSGEQQYVYIEDGDLIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTIFEDLSDYMNSLKDLLKVKANIIYPGHGPVIHNAEAKILEYISHRNNREEQIITVFRDNLEESFSVSELRKMIYKNVPENLHKMAEHNLLLHLRKLEKDGKIFSIASPAKKWRASL
What is the function of this protein?
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA.  The cleavage product contains a free 3' -OH group.  Has no activity with double-stranded RNA or DNA.  Required for normal mitochondrial function and cell viability.
What are the official names of this protein?
Endoribonuclease LACTB2, Beta-lactamase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CYB_PUSHI
Sequence: MTNIRKTHPLMKIINNSFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYMHVGRGLYYGSYTFTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTDLVQWIWGGFSVDKATLTRFFAFHFILPFVVLALAVVHLLFLHETGSNNPSGITSDSDKIPFHPYYTIKDILGALLLILVLTLLVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIMPLLHTSKQRGMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPYITIGQLASILYFMILLVLMPIASIIENNILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PHS_NOCFA
Sequence: MTTELLSDEQIATALQDLPDWTRSGDEISRTVQAESFPAAIALVDRVAEAAERAGHHPDIDIRWRTVTFTLSTHSAGGLTGRDIDLARQIDELAR
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PRMC_DEIRA
Sequence: MQLRDLLTQATARLTRAGVPSPEVDARLLLEHVLGLNRTAFLLRGGEEIGPDAEARAWDSIERRAARVPLQHLTGEVEWGGVRLTSDARALVPRPETEWLLHLALEELRRVEKPRVLDVGTGTGALALGLKAAIPQAEVTATDLSPEALSLARENAALSGLDVKFVEGSLLAGLSGPFNLIVSNPPYLPTADRATADPEVRHDPDLALYAGEDGLDVARPLVAEAAAALVPGGALLLELDPRNAPTLAAELRTAGWQAEVRPDLTGRERFVRARRAGG
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: MNMA3_BACTN
Sequence: MKERNKRVLVGMSGGIDSTATCLMLQEQGYEIVGVTMRVWGDEPQDARELAARMGIEHYVADERIPFKETIVKNFIDEYKQGRTPNPCVMCNPLFKFRVLAEWADKLDCAYIATGHYSRLEERSGHIYIVAGDDDKKDQSYFLWRLGQDILKRCIFPLGDYTKIKVREYLAEKGYEAKSKEGESMEVCFIQGDYRDFLREQCPELDTEIGPGWFVNSEGVKLGQHKGAPYYTIGQRKGLEIALGKPAYVLKINPQKNTVMLGDAEQLQTEYMLAEQDRIVDEQELFSCENLAVRIRYRSRPIPCRVKRLEDGRLLVRFRETASAVAPGQSAVFYDGRRVLGGAFIASQRGIGLVIIENKDKL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 3.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_ECO24
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: LEUD_CAUSK
Sequence: MQAFTRLDGRAAPLSLANIDTDQIIPKQFLKTVEREGLAKGLFYDFRYDGEGNEIADFVLNRPEYKGASVLIAGDNFGCGSSREHAPWALMDYGIMCVISTSFADIFNNNCFNNGLLPVVLKPEEVAVLMDEAKGGNHMVSIDLAEQTVISPSGKSFHFDIDPVRKDKMLKGLDFIGETLMHGGDIDVYESKRALDRPWLEA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RF1_LEPIN
Sequence: MIDRLEKIQEKYLRISEELNQAKDPSSLKNLYKERSRLTPLYLKVEEYLKIYKDRKDAEELIQSEKDEEMHSMLKEEIREANLKLETLEREFEILLLPPDPNSGKNILVEIRAGTGGEEAGLFVADLFRMYSKFADKQKIKTEIIDSSPTGIGGLKEIIFALEDDRAYDLFKFEGGTHRVQRIPSTESGGRIHTSAVTVAVLPEADEEEVQINESDLRIDVYRSSGAGGQHVNTTDSAVRITHIPTGVVVACQDEKSQHKNKAKALRILSARILEKQAEDKKQASDAIKKQMIGSGDRSERVRTYNFPQGRCTDHRIGFTSHNLSAIMEGDLDELIGALTEEDRVRKISETQTH
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIGC_TRAVE
Sequence: MAFKSLLSFVSVIGALQGANAALTRRVACPDGVNTATNAACCQLFAVREDLQQNLFHGGLCTAEAHESLRLTFHDAIAISPALEAQGIFGGGGADGSIAIFPEIETNFHPNIGLDEIIELQKPFIARHNISVADFIQFAGAIGASNCAGAPQLAAFVGRKDATQPAPDGLVPEPFHTPDQIFDRLADASQGEFDPILTVWLLTAHTVAAANDVDPTKSGLPFDSTPELWDTQFFLETQLRGTSFPGSGGNQGEVESPLAGEMRLQSDHTIARDSRTACEWQSFVDNQPKAQQMFQFVFHDLSIFGQDINTLVDCTEVVPIPADPQGHTHFPAGLSNADIEQACAETPFPTFPTDPGPKTAVAPVPKPPAARK
What is the function of this protein?
Depolymerization of lignin.  Catalyzes the C(alpha)-C(beta) cleavage of the propyl side chains of lignin.
What are the official names of this protein?
Ligninase C, Diarylpropane peroxidase, Lignin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ligninase subfamily.
Protein: UFSP1_MOUSE
Sequence: MTAALPSTLELLKDVHLGLPVPCHDPARLALLSGHYLYYHYGCDGLDDRGWGCGYRTLQTLCSWPGGQSSGVPGLPALQGALEAMGDKPPGFRGSRNWIGCVEASLCLEHFGGPQGRLCHLPRGVGLRGEEERLYSHFTTGGGPVMVGGDADAQSKALLGICEGPGSEVYVLILDPHYWGTPKNRCELQAAGWVGWQKVKSVFDSNSFYNLCFTRNL
What is the function of this protein?
Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins.  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
What are the official names of this protein?
Ufm1-specific protease 1, UfSP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
Protein: TDH_ECO81
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMTELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLE1_RHOPP
Sequence: MAPSNTERALPVLAIWAAIGLAYWIDSQKKKKHHLPPGPKKLPIIGNVMDLPAKIEWETYARWGKEYNSDIIQVSAVGTSIVILNSANAANDLLLKRSAIYSSRPHSTMHHELSGWGFTWALMPYGESWRAGRRSFTKHFNSSNPGINQPRELRYVKRFLKQLYEKPNDVLDHVRNLVGSTTLSMTYGLETEPYNDPYVELVEKAVLAASEIMTSGAFLVDIIPAMKHIPPWVPGTIFHQKAALMRGHAYYVREQPFKVAQEMIKTGDYEPSFVSDALRDLENSETPEEDLEHLKDVAGQVYIAGADTTASALGTFFLAMVCFPEVQKKAQQELDSVLNGRLPEHADFPSFPYLNAVIKEVYRWRPVTPMGVPHQTIADDVYRDYHIPKGSIVFANQWAMSNDENDYPQPGEFRPERYLTEDGKPNKAVRDPFDIAFGFGRRICAGRYLAHSTITLAAASVLSLFDLLKAVDENGKEIEPTREYHQAMISRPLEFPCRIKPRNKEAEEVIRACPLTFTKPTSA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pleuromutilin, a tricyclic diterpene showing antibacterial properties (PubMed:28924980).  The geranylgeranyl diphosphate (GGPP) synthase ple4 catalyzes the first step in pleuromutilin biosynthesis (PubMed:28924980).  GGPP is then substrate of the premutilin synthase (PS) ple3 to yield premutilin (PubMed:28924980).  Premutilin synthase is a bifunctional enzyme composed of the fusion of a class II diterpene cyclase (DTC) and a class I diterpene synthase (DTS), with the corresponding domains and active sites containing characteristic aspartate-rich motifs (By similarity).  GGPP is first converted to mutildienyl-diphosphate (MPP) at the class II DTC site (By similarity).  MPP is subsequently further cyclized at the class I DTS site, followed by a 1,5-hydride shift and addition of water prior to terminating deprotonation, to yield premutilin (By similarity).  The cytochrome P450 monooxygenases ple5 and ple6 hydroxylate premutilin at C-11 and C-3, respectively, producing 11-hydroxypremutilin and 3-hydroxypremutilin (PubMed:28924980).  The combination of the actions of both ple5 and ple6 leads to the production of 3,11-dihydroxypremutilin (PubMed:28924980).  The short chain dehydrogenase ple7 further converts 3,11-dihydroxypremutilin into mutilin (PubMed:28924980).  The acetyltransferase ple2 then acetylates mutilin to produce 14-O-acetylmutilin (PubMed:28924980).  Finally, the cytochrome P450 monooxygenase ple1 catalyzes hydroxylation on the alpha position of the acetyl side chain of 14-O-acetylmutilin to yield pleuromutilin (PubMed:28924980).
What are the official names of this protein?
Cytochrome P450 monooxygenase ple1, Pleuromutilin biosynthesis cluster protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL19_STRMU
Sequence: MNPLIQSLTESQLRTDIPNFRPGDTVRVHAKVVEGNRERVQIFEGVVISRKGQGISEMYTVRKISSGVGVERTFPTHTPRVEKIEVTRHGKVRRAKLYYLRALQGKAARIKEVRQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: KPRS1_LISIN
Sequence: MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEDSPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, RPPK 1, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 1, Phosphoribosyl diphosphate synthase 1, Phosphoribosyl pyrophosphate synthase 1, P-Rib-PP synthase 1, PRPP synthase 1, PRPPase 1.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ACTSZ
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGSVKEAGGQIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRYNDAVLRNVIIRTKHAVTEASPMAKAKDERKVAVAEVETNNFEDAEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PYRH_SALTY
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDNYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPSATMYDQLTYSEVLDKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_METVS
Sequence: MDLGTTKYIIYTELIADGYVEKHDVIGAIFGQTEGLLSTELDLRDLQKSGRIGRIDVELENVNGKSFAKITLPSSLDKVETSILAATLETIDRVGPCFATVKIANVEDIRVSKRQYITNRARHILRQLMDEMVDTYEITEEIKESLRTEEIMEYGPENLPCGPNILHSDSIIIVEGRADVLTLLRCGIKNAIAVEGTSVPKTIMEISKKKTTTAFTDGDRGGELILKELLQTCDIDYVSRAPYGKEVEGTSKKEIMKCLRAKVPVEQIIGEKYKNIVESNPVLNEELVEKITPKYIEEVTHSSKEKNELEKTFKPEIEKETVVIEKIKSFEKKTIDADEKTILQENSNLEKKYNGVKEILEGIKNTGLVKFVVDGKEKTNSFKEFLTNIQEIKNMDFFAADMPITQKIVDLLHDKTPIIVGTEIKVTKKPVNLRLFSFDEIME
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: RCOR1_MOUSE
Sequence: MPAMVEKGPEVSGKRRGRNTAASAASAAASAASAAASAAASAGTASASAAAAASAAAAPNNGQNKSLAAAAPNGNSGSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAAVPDFDPAKLARRSQERDNLGMLVWSPNQSLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQKREREESEDELEETNGSNPVDIEIDPNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSIKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKDETNGPANQKPVKSPESSIKIPEEEDEAASVLDVRYASAS
What is the function of this protein?
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells.  The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.  In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.  Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates.  It also protects KDM1A from the proteasome.  Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
What are the official names of this protein?
REST corepressor 1, Protein CoREST.
What is the protein family that this protein belongs to?
Belongs to the CoREST family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_BACFN
Sequence: MNTEILGVAVQIVLMVVLAYPLGRYIARVYKGEKTWSDFMAPIERVIYKICGINPQEEMNWKQFLKALLILNAFWFVWGMVLLVSQGWLPLNPDGNGAQTPDQAFNTCISFMVNCNLQHYSGESGLTYFTQLFVIMLFQFITAATGMAAMAGVMKSMAAKSTQTIGNFWHFLVISCTRILLPLSLVVGFILILQGTPMGFDGRMQLTTLEGQEQMVSQGPTAAIVPIKQLGTNGGGYFGVNSSHPLENPTYLTNMVECWSILIIPMAMVLALGFYTNRRKLGYSIFGVMLFAYLAGVFINVGQEMGGNPRISEMGIAQDHGAMEGKEVRLGAGATALWSVTTTVTSNGSVNGMHDSTMPLSGMVEMLNMQINTWFGGVGVGWLNYYTFIIMAVFISGLMVGRTPEFLGKKVEAREMKIATFVALLHPFVILVFTAISSYVYTHHPDFVESEGGWLNNLGFHGLSEQLYEYTSSAANNGSGFEGLGDNTYFWNWTCGIVLILSRFIPIVGQVAIAGLLAQKKFIPESAGTLKTDTVTFAVMTFAVIFIVAALSFFPVHALSTIAEHLSL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_MYCPA
Sequence: MADDPGSSFTTVWNAVVSELNGEPVADGGAANRTTLVTPLTPQQRAWLNLVRPLTIVEGFALLSVPSSFVQNEIERHLRAPITDALSRRLGQQIQLGVRIAPPPDDVEDAPIPPAEPFPDTDAALSADDGADGEPVENGEPVTDTQPGWPNYFTERPHAIDPAVAAGTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDKSLAEIVLRDLIADASTMQISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BACC2
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVTAAIEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGIGNTEQIAARIGQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLESGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROC1_NICPL
Sequence: MASSASSLHFLSLTPQTLLLPKPTSQTTSLSFFSLPPSSLNLSLSSPSSCFSSRFVRKVTLPDFDQIEDVEDGDEGVEEERNFSPDLKIFVGNLLFSADSAALAELFERAGNVEMVEVIYDKLTGRSRGFGFVTMSSKEEVEAACQQFNGYELDGRALRVNSGPPPEKRENSSFRENSSFRGGSRGGGSFDSSNRVYVGNLAWGVDQDALETLFSEQGKVVDAKVVYDRDSGRSRGFGFVTYSSAEEVNNAIESLDGVDLNGRAIRVSPAEARPPRRQF
What is the function of this protein?
Could be involved in splicing and/or processing of chloroplast RNA's.
What are the official names of this protein?
30 kDa ribonucleoprotein, chloroplastic, CP-RBP30.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1309_HAEIN
Sequence: MKIHLIRHNTTLEFNNETSLLDHLEKNNIHHEYQCRSGYCGSCRVKIKKGKVSYKEMPLAFIQPDEILLCCCHVESDIEIDL
What are the official names of this protein?
Uncharacterized ferredoxin-like protein HI_1309.
Protein: OAZ1_BOVIN
Sequence: MVKSSLQRILNSHCFAREKEGDKPSATVHATRTMPLLSLHSRGGRSSESSRVSINCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNVTEELTSNNKTRIFNVQSRLTEAKHINWRAVLSNSCLYVEIPGGALPEGSKDSFAVLLEFAEEQLHVDHVFICFHKNRDDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEE
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.  Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC.  Stabilizes AZIN2 by interfering with its ubiquitination.  Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter.  SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.  Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
What are the official names of this protein?
Ornithine decarboxylase antizyme 1, ODC-Az.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.