PharMolix/UniProtQA huggingface dataset:
Protein: RLUA_SALTY
Sequence: MGMENYNPPQEPWLVILYQDEHIMVVNKPSGLLSVPGRLEAHKDSIMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYNVVEFAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEALSLAPRLQLHAEMLTITHPAYGNSMTFKVPADF
What is the function of this protein?
Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
Dual-specificity RNA pseudouridine synthase RluA, 23S rRNA pseudouridine(746) synthase, Ribosomal large subunit pseudouridine synthase A, rRNA pseudouridylate synthase A, rRNA-uridine isomerase A, tRNA pseudouridine(32) synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: HIS7_BRUA2
Sequence: MTAESTRKASIERSTKETSIAVSVDLDGVGKFDITTGVGFFDHMLEQLSRHSLIDMRVMAKGDLHIDDHHTVEDTGIALGQAVAKALGERRGIVRYASLDLAMDDTLTGAAVDVSGRAFLVWNVNFTTAKIGTFDTELVREFFQAFAMNAGITLHINNHYGANNHHIAESTFKAVARVLRAALETDPRQKDAIPSTKGSLKG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXO5_ZYGRC
Sequence: MLRSRTKCANSLLQIRKKSHLRQVISFSSRELGLTEHELETIDKLPFFDQDRVNTRKRYPTTKRQAYLNEKLPAVKLLFGEDPQYPGFISHSLPSMMPIPFEATQGTDEETIANRLSVTKLLTKSWCELRHAYDVYAKIPMFEGKPIIKGKEEHQRLEDETHSLAEEQRAFEKDFEVVIPDDDFHKLAESWFASLVKMVNLFTDGEAREVLCHGYLNKKKARLVEGPIIGDDDDDVLVSGIIDHLILKLRDVPVSNNVLPLRLENAIVSKNCEDIAVVFDQLERAGPNLQNKFEIMVSDVKTRFMRKIPSQPSVLKASKLQVMYYRYFMEVLGQNPQETYNKLLINAQRRGFDVNRFIDPAKVLSMMATDDMIRMDMYRLKNGDAIGFEPFDDSELNVSESATYDMSDYHDIITDARVIQKYSDFFEPWAKPVTLKYFAARLAQMYHHLRPLLSNKLMIEYYYNGDNFHNIIFEFDPKLLRESSSDSAKFWFGQRDIEPISRNLKNFLTFCKYCDYESVCSWKRGGNDMCKELGTDLAKIQKS
What is the function of this protein?
Single strand DNA specific 5'exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DNAK_STAAS
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL18_STREM
Sequence: MKIVISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HTRA2_DROME
Sequence: MALRGSHRLEVIFKRCIASPVLHSHAANRRSSQLAIKEGDPNSNGNSGQYQQNGEQKEKGWRRLVRFFVPFSLGAVVSAAIIQREDLTPTIAASKMTGRRRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPEDP
What is the function of this protein?
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein.  Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism.  Can antagonize antiapoptotic activity of th by directly inducing the degradation of th.
What are the official names of this protein?
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, DmHtrA2, HtrA2, Omi stress-regulated endoprotease, dOmi.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Predominantly present in the intermembrane space (PubMed:17397804, PubMed:18259196). Released into the cytosol following apoptotic stimuli, such as UV treatment (PubMed:17397804). The extramitochondrial protein does not diffuse throughout the cytosol but stays near the mitochondria (PubMed:17397804).
Protein: SYL_ECOLC
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRIWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_SHIDS
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTAGILTLLPVALRESVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSRAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIGTIIPVLDELRAQGMKLSGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_DEIGD
Sequence: MKDFSKVRIAIASPAKIREWSFGEVEKPETINYRTLKPEREGLFDERIFGPIKDYECACGKYKRQRYEGKVCERCGVEVTSSKVRRYRMGHIDLATPAAHIWYVKDTPSKIGTLLDLSAAQLEKVLYFSSFLVTDPRNAQKDGRPLRRGELLSDDEYRELRFGRQETYTLPSGTEAAVRDGEYVTRGQVLGGNVVSKMDGLAQYRFPRRAEIAYAEEAEASLPLPSDVLVQQDSFRPGEILAELEGDVQITAPVDGTAFLLDMGEDSVLVELRDSAAEDAAQGEVLARVYIPHGMNVQVAEGEVVEAGSVLATAAAGDRLRVSRDSRLSNVNFPKKKGDVKVTAHWTRRVEYRIEPQMHVLVGDGSEVRKGQKVVGAIDKEEEVIAEADGVITLHAPASIIVSKARVYAYQDEPLVVNGDRVEPGDELADSGNLRSEISGRVEIDLVRKQVRVIESYDFEAKMGAEAVKELLDDLDLDQLEAELSEQMKDNSRHKRAKARKRLEVVRAFKRSGNHPSWMILETVPVMPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLIGQGAPDMIIRNEKRMLQEAVDALIDNGRRGSPVTNPGSDRSLRSLTDLLGGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGVPKRMALELFKPFLFKVLEEKGEVTNIKQARKMLERYRDTRDSVWDALEEVIEDKVVLLNRAPTLHRLGIQAFEPVLVEGQSIQLHPLVCEAFNADFDGDQMAIHVPLSAQAQAEARIQMLSAHNLLSPANGEPNVKPSRDIILGIFTLTQLRKDNLGAGSEFANEQDALKALDEGRVALNTPIRVNGVETSPGRLKYVFSSPDEAIMAVDRGEIDYQDHVRIRLNGTVYETSAGRVMFRRLVQEALGAQGHLVDTLVNLDTAYEKDSLKDMVMACYKELGIEATAGLLDALKDSGFKLSTISGITIGIDDIVLPPNKRELLAEADEKLAAIEQNYEFGFMTDEERYKQVVQLWNDTTDEVKNAVFENFSRNYPFNPLWIMSQSGARGNPQQIRQLAGMRGLMARPDGSTIEVPIRASFREGLTVLEYFISTHGARKGGADTALRTADSGYLTRKLVDVAHEVVVRDVDCGTTDYTVMPLGTTDERTGEWRTRKGSEIETAIYGRTLTADVELSDGRVIPAGQMLSLEDVKAITRDAKAIGEVFVRTPLNCRVRAGVCQKCYGYDLSQAKPVSLGEAVGVVAAESIGEPGTQLTMRTFHTGGVAGGGDITMGLPRVIELFEARKPKTQAVVADRDGVVRIEEEEERYLVRIEAEDEAFSSKTPMKISKSLRLIVRDGDHVEAGQPLTRGAINPHDLLLYKDTDAAQRYLVEEVQRVYRSQGVKVHDKHIEVIVRQMLRYVEITDGGDTDLLEGQTVERWEVDQANDALPEGKTPASWKPVLLGITKSSLTTKSWLSAASFQHTTHVLTEASMRGQVDELIGLKENVILGKLIPAGTGLTTVREMQVADERTLEKYGQTSVSTDAVTGSQRYDDTRPSSTSINPSYGD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: VP74_NPVOP
Sequence: MAVLTAVDLTNASRYAGHMHRLEFINRWRERLPHILIDYTLRPASSDDDYYVPPNLRNRALAVKLAFSRRGCDSMSCFPFHETGVVSSQTPFAYTQTSETSVAYAQPACYHLDRAAAMREGAENEVQSAEFTYTPNNQCVLVDSTSKMYFNSPYLRTEEHTIMGVDDVPAFNVRPDPDPLFPERFKGEFNEAYCRRFGRDLINGGCSFRWWESLIGFVLGDTIYVTFKMLANNIFSELRDFDYAAPSPLLPPRPAADSNAVLAQWRAVRDRAVDWDFEKQFSEAPTLQQLGMDANGVLMQLSYTAETGFTKTPIAYSARGAVRVARESRAADRAMSDDDLEAIVASFLEEYALVFGIATDIGFDMLLTAFKAMLKKINTALIPALKRMLVGTSQRVTVRLLGETYKAALVHSMNRIAIKTLTTAAKALTRVAIKASSVVGIVLILFTLADLVLALWDPFGYNNMFPREFPDDLSRTFLTAYFETLDSNTSREIIEFLPEFFADIVETDDDATFQSLFHLLDYVAALEVNSDGQMLALDESDEIKDFDEATLVGQALASSSLYTRLEFMQYTYRQNTLLAMNKNNNKLNGVIAGLFLTNTAVALAAFIAHKELTFFVYFAIFLMLAFYYLVKEPYEYFKTVDLLF
What is the function of this protein?
Essential for virulence of baculovirus occlusion bodies for insect larvae.
What are the official names of this protein?
Protein p74.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p74 family.
Protein: Y616_AQUAE
Sequence: MRLKKLPIRRKMPMELAYIEKLFREEVGLDIKEHKDKAEQISETVVEIYEELLRKGIENANYNGRDYVSYYDLPITEDLERYMNRFIQDRGEEVLKAFVDYLAKLEEELLKAEEALPPLDEELHQKKADILGGIMLMFASVAKQINGDRKLYAESIPVTREVLRTMI
What are the official names of this protein?
Uncharacterized protein aq_616.
What is the protein family that this protein belongs to?
To A.aeolicus aq_328.
Protein: CHM1A_MOUSE
Sequence: MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALQQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSAMDLQKVSAVMDRFEQQVQNLDVHTSVMEDSVSSATTLTTPQEQVDSLIVQIAEENGLEVLDQLSQLPEGASAVGESSVRSQEDQLSRRLAALRN
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  Involved in cytokinesis.  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.  May also be involved in chromosome condensation.  Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin.  May play a role in stable cell cycle progression and in PcG gene silencing (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, CHMP1a.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Nucleus matrix. Note=The cytoplasmic form is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with the chromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized by nuclease-resistant condensed chromatin.
Protein: PLTA_PSEF5
Sequence: MSDHDYDVVIIGGGPAGSTMASYLAKAGVKCAVFEKELFEREHVGESLVPATTPVLLEIGVMEKIEKANFPKKFGAAWTSADSGPEDKMGFQGLDHDFRSAEILFNERKQEGVDRDFTFHVDRGKFDRILLEHAGSLGAKVFQGVEIADVEFLSPGNVIVNAKLGKRSVEIKAKMVVDASGRNVLLGRRLGLREKDPVFNQFAIHSWFDNFDRKSATQSPDKVDYIFIHFLPMTNTWVWQIPITETITSVGVVTQKQNYTNSDLTYEEFFWEAVKTRENLHDALKASEQVRPFKKEADYSYGMKEVCGDSFVLIGDAARFVDPIFSSGVSVALNSARIASGDIIEAVKNNDFSKSSFTHYEGMIRNGIKNWYEFITLYYRLNILFTAFVQDPRYRLDILQLLQGDVYSGKRLEVLDKMREIIAAVESDPEHLWHKYLGDMQVPTAKPAF
What is the function of this protein?
Involved in the biosynthesis of the antibiotic pyoluteorin (PubMed:16162666).  Catalyzes the dichlorination of the pyrrole ring of pyrrolyl-S-PltL, generating the 5-chloropyrrolyl-S-PltL intermediate and then the 4,5-dichloropyrrolyl-S-PltL product (PubMed:16162666).
What are the official names of this protein?
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase, FADH2-dependent halogenase PltA.
What is the protein family that this protein belongs to?
Belongs to the flavin-dependent halogenase family.
Protein: H4_MORAP
Sequence: MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRSVLKVFLENVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ADIPO_HUMAN
Sequence: MLLLGAVLLLLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHDTN
What is the function of this protein?
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities.  Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion.  Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects.  Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway.  May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
What are the official names of this protein?
Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: GKN1_MOUSE
Sequence: MKLTMFVVGLLGLLAAPGFAYTVNINGNDGNVDGSGQQSVSINGVHNVANIDNNNGWDSWNSLWDYENSFAATRLFSKKSCIVHRMNKDAMPSLQDLDTMVKEQKGKGPGGAPPKDLMYSVNPTRVEDLNTFGPKIAGMCRGIPTYVAEEIPGPNQPLYSKKCYTADILWILRMSFCGTSVETY
What is the function of this protein?
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
What are the official names of this protein?
Gastrokine-1, 18 kDa antrum mucosa protein, AMP-18, Protein CA11 homolog.
What is the protein family that this protein belongs to?
Belongs to the gastrokine family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Golgi apparatus. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus.
Protein: LEXA_ENTFA
Sequence: MRVLAKRTETRQLEVLKYIYEQVELKGYPPTVREIGKAVDLSSTSTVHGHLARLEKKGLILRDPTKPRAIELTPEGLEKIGIQPTTIPMLGVVTAGEPILAVEEASDFFPLPPDLRTEENALFMLTIRGESMINAGILDGDQVIVRKQSNANNGDIVIAMTDEDEATCKRFFREVDHIRLQPENDALAPILLDNVTILGKVVGLYRNHI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: FABZ_YERPA
Sequence: MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVKPDVVKPDVVNPVVKES
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIA_MECPA
Sequence: MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
What is the function of this protein?
Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time.  It only minimally suppresses the amidolytic activity of thrombin.
What are the official names of this protein?
Triabin, Thrombin inhibitor.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Triabin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROC_CAMFF
Sequence: MNTFGSKLRLTTFGESHGKAIGGVLDGFPAGVAIDEEFLQSEMDKRKPGGKYATSRKEADEVEILSGIFEGFSTGTPIGFIIKNSNQHSKDYDSIKDLFRPGHADFTYFSKFGVRDHRGGGRSSARETAVRVAAGAFGAMMLKEFDIDIKSGVFSIGKLKSNKIDFEFASKSEIFMLDSDIEEDAKNLILDVKNSNDSVGAATLTIINGVPAGLGEVLYDKLDARLAAAMMGINGVKGVEIGLGSQASFILGSQNNDFMDKNGFMSNNAGGILGGISNGEPIMIKTYFKPTPSIFKDQPTINLNGDEVTCALRGRHDPCIGIRGSVVANAMARLVISDMLLLNASSKLSNLKKIYS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UVRC_BORPA
Sequence: MPDDFNLKSFLADLPHLPGVYRHLDAAGEVMYVGKARDLKKRVSSYFQKNLASPRIAQMVAKVASVDVTVTRSEAEALLLENNLIKSLRPRYNILFRDDKSYPYLLITGHAWPRIAYYRGATSKRGQYFGPYPNSWAVRETIQILQKVFRLRTCEDTVFANRSRPCLLHQIGRCSAPCVGVIEAGDYAHDVQRAVRFLNGEAREVMDEIEARMLQASTELRFEEAAVLRDQMGSLSKVLHQQTMENVGGDDTDVIAVASAGGKICVNLAMVRGGRHLGDKPFFPTHAEGEQPAQVLEAFVAQHYADGAMPPVLVCSHALPDSGLVGLLAEQGGTRAARVLTRPQGVRRSWLEQAQKNAEMALARALTESGARAGRTLALAEALDLDTDEESLDALRIECFDISHTAGEATQASCVVFLHHDMQPSLYRRYNIVGITPGDDYAAMRQVLTRRFGKVADGEAPMPGLVLIDGGKGQVEVARQVFVELGLDIQSLVGVAKGEGRKVGLETLVFADGRPPVALGKESAALMLIAQVRDEAHRFAITGMRARRAKTRNVSRLEEIEGIGARRRQRLLARFGGLSGVSSASIEDLASVEGISQELAVRIYDALHG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_SALTI
Sequence: MGQSKKLNKQPRSLSPLVLLSGISKSFDGKEVISQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDAGHIMLDNQDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEIAPRVTDALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRNGVIEQDGTPREIYEEPKNLFVAGFIGEINRFDATVIERLDEQRVRASVEGRECNIYVNFAVELGQKLNVLLRPEDLRVEEINDDNHIEGLIGYVRERNYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAISWVESWEVVLADEEHK
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMH_ECO24
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SALPA
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y1331_METJA
Sequence: MVASMATTYELRIYGNVECAEFIDKVESLGKLLDVNGVVYVYKDSVRILANFPNEKKRQLFKEIIKDLEDDGGLIKVERIEERDLNTYIEFPNGLNKISTNELKEINKKLDKTISYLENIFNALEKQIKVSEEIRDILKDTFEV
What are the official names of this protein?
Acylphosphatase-like protein MJ1331.