PharMolix/UniProtQA huggingface dataset:
Protein: MNMC_LEPIN
Sequence: MLTWKNNLTPVSEQFDDIYFSPENGLEETKHVFIKGNDLYNRWRNWNIQNAFCILELGFGTGLNFLTTWKEYLEYKDRFRLHFISIEKFPLNREEISKALSIFSELVEIKKEFLSSYQDLIPGMNYFQFLGGKIHFSLFLGDVSSALCEISGKVDAIFLDGFAPSKNPEMWDKSVLENLKYVSKKGTTLSTFTVARMVRDSLSFSGFKLEKRPGFGRKREMLIGSYSDSFLESNPKEKPWCKRAYPELQIKTVAIVGAGIAGTTLAYSLSRRGIQVFLIDPSGIAKETSGIPMAISHPHLTKIPGPISLFTLRAFRYALSFLSSFADQNFFEKTGLFHSVTQEMDSERLQKGIENHKLSEEIVFWKPIASKFQNGDFLENEPGVFFRNGFWTRPESIAKKCAEQPGVEFIKGTASRIEQDGTSWKLLIQESGHEIVANSIIFCNSHSIGKLIASLFEGEEPFPIRKVRGQLISLKETEKSSRISNILCAEHYLTPSILGEHILGSTFDEFDLNPLPQKKDTDRLLEFVQNKYPSLNFDSSCVLIEKVGLRAQTPDRLPILGPVFDPREFRKIYKEIDLPKNRNKKFPNLKTIQGLYVFGGLGSRGILSSFLGSEIMASLILGEPVPVESSVLEHLHPARFLYRKVRK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAT_FMVD
Sequence: MSKDHLDFPHVYKKNKVLKLKPLDLSKNPRSYYFSSQNGSIQAIINHCNNINQITARNWLKLSKVLSYFGLEKDTSDSISKNKSPFNRFLKDISHIFREGEGSTKKASELGEILEKIKNLDLKIENLNKRIPDNLVTKALIKELVKDFDERLTEVRDDIKKVIG
What is the function of this protein?
This protein is involved in virus transmission.
What are the official names of this protein?
Aphid transmission protein, Atf, Protein 2.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae ORF II family.
Protein: SYFA_ECODH
Sequence: MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_BIFLD
Sequence: MSPEALSELISSIAHNLVAAGQAGALTDELIPPVDKLAVMRPKDRAHGDWASNIAMQLAKKAGMKPRDLAEPFAAALAEADGIAKVEVAGPGFINITLDSASAAAVVDTVLAAGAMTDTDKHLNKVNEYGRNAHLGGQTLNLEFVSANPTGPIHIGGTRWAAVGDAMARVLEANGAKVVREYYFNDHGEQINRFAKSLVAAWAEANNLGEAGYQTETPCDGYKGAYINEIAARVQAEAESDGVDLTALAHQDQGLNDDGEPLGEADTEVREEFRKRAVPMMFDEIQKSMKDFRVNFDVWFHENSLYADGKVDAAIEELKSRGDIFDKDGATWFESTKHGDDKDRVIIKSNGEFAYFAADIAYYWDKRHRAENPADVAIYMLGADHHGYIGRMMAMCAAFGDEPGKNMQILIGQLVNVMKDGKPVRMSKRAGNVVTIDDLVSVVGVDAARYSLARSDYNQNFDIDLALLASHTNDNPVYYVQYAHARSKNVDRNAAVAGISYEGADLALLDTEADGEVLAALAQFPSVLATAADDRQPHKVARYLEELAATYHKWYNVERVVPMALTDPETRGDDEARKALEIAKNPEPARAAARLKLNDAVQQVIANGLDLLGVTAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPHR_SALSA
Sequence: MSFLMDSVIMFTSQVLFFGFGWLFFMRQLFKDYEVRQYVVQVVFSITFAFSCTMFELIIFEILGALETSSRYFHWKFNLYVILLVLIFVVPFYIGYFVVSNIRLLQRQKLLFACVVWFTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTESDILALERRLLQTMDMIVSKKKRIAMTRRQMYQRGEDQNKQTGFWGMIKSVTSSPPGSENLSLIQQEVDALEELSRQLFLETVDLQATKERIEYSKTFQGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLVLAQIMGMYFVSSVLLMRMSMPLEYRSIVTEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMTP
What is the function of this protein?
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (By similarity).  Plays a role in lymphocyte development (By similarity).
What are the official names of this protein?
Golgi pH regulator, Protein gpr89.
What is the protein family that this protein belongs to?
Belongs to the Golgi pH regulator (TC 1.A.38) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RNC_ECOSE
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCOR_HUMAN
Sequence: MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTNGERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVPTDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKPSVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPFLEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
What is the function of this protein?
Transcriptional corepressor.  May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3.  This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.  Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions.  Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
What are the official names of this protein?
BCL-6 corepressor, BCoR.
What is the protein family that this protein belongs to?
Belongs to the BCOR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YACL_ECO5E
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: YNB2_SCHPO
Sequence: MSLNVDIGLGTYDFSKWGYIDVHKIKEVHIYDFDNTLFQTPLPNANIWSNQAIRILMAFNILANGGWFFDPHVLAATGDGVEVEEKRAWEGWWNEKIVSQARESIRRPDVLAVLLTGRNEGFRGIVEKIIASKGLDFQGVVFKLQAPDGFWPQTLNFKLWFFNEVYRHFLYINSTRIYEDRPSHIEAFSAWLTERKKKNKNADFEIIAVAEPPKYLKFKVEIALVRGMLTAHNLKAPSLKLPLYKFVKNVIATVVTVPVAELHHIRNAFFNIPIAEIMESVSANSSRRNSHDSNSTIICEPEYPPDTSFNSSPGRLWIVTAIGRYRDEYWTVRAEAAEGYDCEKIHEIDVADIPSLYGTILYVSMSTGIVKSEIGDIGAQQWKTLAPSERWILRTNIRKECTYDIRYKRPYVSSLKYSDDDLTAGRASPMTGPTKRK
What are the official names of this protein?
Uncharacterized protein C4.02c.
Protein: WHIA_EXISA
Sequence: MSFASDVKKELTQLEVTDAEAKAELSALVRMNGVISLALGRGMTLDVSTENASIARRIYSLMKRLYDHPLDLFVRKKMRLKKNNVYIVRVSQHAETMLRDLEILGENYEMIRTLNSDMTGDENLARAYLRGAFLAGGSINHPKTSSYHLEIYSLYENHNQALRDLANRFELNAKTLERKKGHILYMKESEKISDFLKLIGATRGMLEFEDARIIKDMRNSVNRLVNCETANLNKTVGAALRQVENIKFLERTVGLDVLPKKLREIAELRVTHQDVSLQELGEMLESGPISKSGINHRLRKIDQIAERVRSGDEIASS
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: YGFZ_ECO7I
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVRESQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANIFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_PARPJ
Sequence: MPPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFVDSTEKAYATLEKINEAIVQDGRRPIVFTTLVDSASNQIVKGSNALVLDMFQTFVEPLEQELELKSSHAMGRGHQNADTEEYKNRIEAINFSLAHDDGQSNRNLADADVILVGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPTPLLAHRQKMFGLSIDPQRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGIKWLSSTHKSIEEIATTILQEIKLDRPSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: HUTI_SOLUE
Sequence: MSDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAGDTEVIDAGWRVVLPGFIDAHTHPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTREAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDELRILKTIRLLNAERRLRYVPTFLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAAQSLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVYNLGSARYPAARDMIARGMAVVLATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTVNAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGREPANAVYLAGQCVYRRSA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y950_TREPA
Sequence: MWLPHAFLRVVSPSALRLMPANGCAVPAGCVQCSNRDVGFATGARVFLCCQTGVRIVGSLLLFGAAMEKPRAQSRTTAFKRGVSCTQKFSRSRF
What are the official names of this protein?
Uncharacterized protein TP_0950.
Protein: PUR7_RHOCS
Sequence: MTRRRRIYEGKAKILFEGPEPGTLVQYFKDDATAFNAQKKGVITGKGVLNNRISEYLMMKLGEIGIPTHFVRRLNMREQLIREVEIIPIEVVVRNVAAGSLTKRFGIPEGTQLPRSIVEYYFKNDELGDPMVSEEHITAFGWAAPQDLDDMLALALRVNDYLSGLFLGIGLRLVDFKVEFGRLWENEEMRIILADEISPDNCRLWDVKTNEKLDKDRFRQDLGNVAEAYQEVAKRLGIMPEAGPGDMKAPKLVQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: KIF2B_BOVIN
Sequence: MASQLFRPLTPRLSSLTPVKPHFGHLQAGISVAIQRTDGRIHLAVVTEVRRDNAWVTVEWAEKGVKKGKKVALETIFLLNPALALAGPAAQGRASRSVSLAPPSVIGDQRTAARWAGKIPQRNETPSGDSLAVRVPSSPCLMTQRKSACLREIEKLQKQRERRRRLHREIRAQRARDADTGNAHYEIRRLIEECRRRLRGGRISGPEPRDGRRICVCVRKRPLNRQEATREDLDIVTIPSDNVVMVHESKQKVDLTRYLENQTFCFDHAFDDTASNELVYQFTDQPLVESIFRHGMATCFAYGQTGSGKTHTMGGGFSGRDQDCSKGIYAMVAQDVFLLLKTSAYEKLNLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGSQQIQVVGLQEQEVCCVEDMLNLVELGNSCRTSGQTSVNAHSSRSHAVFQIILKSRGKLHGKFSLVDLAGNERGADTAKANRKRQLEGAEINKSLLALKECIRALGQNKSHTPFRASKLTQVLRDSFIGQNSSTCMIATISPGMASCENTLNTLRYANRVKEITLNLRPRHRCLYPAEREMPRVLENHIRNSEMSLQGDEFIRIPCLQSEEEKETEGIKVLSSPLVDTTISWKEASQWPDNKIQDTSDEVNCNVDFCIAQLLSILEKKIDILTEIRRKLKLLQADIQKENRHGEVNGERSDLK
What is the function of this protein?
Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement during mitosis.  Has microtubule depolymerization activity.  Plays a role in chromosome congression.
What are the official names of this protein?
Kinesin-like protein KIF2B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.
Protein: CHM1B_CHICK
Sequence: MSNMEKHLFNLKFAAKELNRNSKRCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKSMNLEKISALMDKFEHQFETLDVQTQQMENTMSNTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGTSVASAEQDELSQRLARLRDQV
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.
What are the official names of this protein?
Charged multivesicular body protein 1b, Chromatin-modifying protein 1b, CHMP1b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Late endosome membrane; Peripheral membrane protein.
Protein: VKTB2_DABSI
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPTFCNLAPESGRCRGHLRRIYYNLESNKCNVFFYGGCGGNDNNFETRDECRQTCGGK
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin.
What are the official names of this protein?
Kunitz-type serine protease inhibitor B2, BPTI-2, Trypsin inhibitor 2, Trypsin inhibitor B2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: TCYN_ECOLI
Sequence: MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGAAKALFADPEQPRTRQFLEKFLLQ
What is the function of this protein?
Part of the ABC transporter complex TcyJLN involved in L-cystine import (PubMed:25139244, PubMed:20351115, PubMed:25837721, PubMed:26350134).  This high affinity cystine transporter is involved in resistance to oxidative stress by forming a L-cysteine/L-cystine shuttle system with the EamA transporter, which exports L-cysteine as reducing equivalents to the periplasm to prevent the cells from oxidative stress.  Exported L-cysteine can reduce the periplasmic hydrogen peroxide to water, and then generated L-cystine is imported back into the cytoplasm via the TcyJLN complex (PubMed:20351115, PubMed:25837721).  Functions at low cystine concentrations (PubMed:26350134).  The system can also transport L-cysteine, diaminopimelic acid (DAP), djenkolate, lanthionine, D-cystine, homocystine, and it mediates accumulation of the toxic compounds L-selenaproline (SCA) and L-selenocystine (SeCys) (PubMed:25139244, PubMed:26350134).  Could also facilitate threonine efflux (PubMed:28911185).  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
L-cystine transport system ATP-binding protein TcyN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PPR32_BOVIN
Sequence: MMGKLPLGVVSPYVKMSSGGCTDPLKFYATSYCTAYGREDFKPRVGSHRGTGYKSNYRPVVFYQPHLDALDNTATGEQGCNNFQTVTSQSYRPLEVPDGTHPLPWNLHQTNSGYSREKASAVTPIKEVRKVHFDTQDYGPQAITGLEPKDAPLLHQQQNKGSLEWENAGHGPRFMTSEYNSKYLKEPSHQPDLLQKNSVGAKEETGFTEESNKNPIVFQPPSQALPGDPVLLPGRSVTKSDFLPISHPHGDEFLPVLARGSERETGFSRVNERTLNPRVPPPCPEPSSMNHWQFQSPQRMQQTNVALLGRETVGNKEPSGFSLNNPSYVRSPYDPDMDNRYLTTYNQGYFENIPKGLDREGWTRGGLQPQKPGGYALNQPVTRLEATPTPTESLRRLHPHLGRTLISVDPFYRTAPPSGHVSRFTAPN
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 32.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm. Note=Localized to the cilia of polarized ependymal cells during development and at the adult stage. Preferentially locates between the peripheral microtubules of the axoneme and the ciliary membrane.
Protein: RL10_STRU0
Sequence: MSEAIIAKKAEQVDLVAEKMKAAASIVVVDSRGLTVGQDTELRRSLRESGVEFKVIKNSILSRAAEQAGLGDMKDLFVGPSAVAFSNEDVVAPAKIINDFAKTADALEIKGGAIEGAASSKEDIQALASLPNREGMLSMLLSVLQAPVRNVAYAVKAVAESKEDVA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: FABH_PERMH
Sequence: MGDIKAEIKGIGINIPERILTNFDLEKFLDTSDEWITTRTGIKERRIAEEWEKASDIALPAAKEAIENAGLTPKDIDAVIVATSTPDMTFPSTACFLADKLGSSKPMAFDISAACSGFIYGLTLANSFIKSGQFENILVVGAEVFSQIIDWNDRSTAVIFGDGAGAVVVSKSDGESDILSAVMKSDGSHWGSLYCPVGEKLRMRGRETFKLAIKSMETASKKALQKAGLTLEDIKLVIPHQANIRIINALAERMELPEERVYSNIHRYGNTSAASIPIAFYEAWKEGKIDKGDHILLTAFGGGLTWGAIVLKF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_BURPS
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVIAVDRYPNAPGHQVAHRAHVIDMTDPDALRALVDAERPHLVVPEIEAIATDALAAIEAAGVCEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFAQSFDEFAAAVARIGFPCVVKPVMSSSGKGQSVVRSEADIEPAWRYAMAGGRVNHGRVIVEGFIRFDYEITQLTVRAIDPASGQTRTSFCAPIGHLQVAGDYVESWQPQPMSAKALERSRDIAHRVTSALGGRGIFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVEPALATPAASAVIYGGLDEAGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALATGANVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: EXP12_ORYSJ
Sequence: MARSAFFFHCVAAVAACIAATAAALSGTATFYGGSDASGTMGGACGYGNLYSTGYGTNTAALSSALFNDGAACGECYQITCDQSNSKWCKAGTSVTITATNLCPPDYSKPSNDGGWCNPPRQHFDMAQPAWEQIGVYRGGIVPVNFQRVSCTRKGGVRFTINGNSYFELVLITNVGGPGSIKSVQIKGTKTGWVTMSRNWGANWQANNYLNNQAISFSVTSTAGKTLVFEDVAPSNWQFGQTFTSGVQFY
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A12, Alpha-expansin-12, OsEXP12, OsEXPA12, OsaEXPa1.15.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: PAT15_SOLTU
Sequence: MATTKSFLILFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYFEHGPHIFNYSGSIFGPRYDGKYLLQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPIYFPPHHFVTHTSNGATYEFNLVDGGVATVGDPALLSLSVATRLAQEDPAFSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAEEAAKWGPLRWMLAIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLVQVGETLLKKPVSKDSPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin-15.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.