PharMolix/UniProtQA huggingface dataset:
Protein: NANC_ASPNN
Sequence: MLSPVEVDLEAYDISRVSGFLPDKCPLRKLPDPYYVPWERLTAHLEPLIRAKRLQHELDQMPVLGITRLTSQPMRRRAYVLLSFLAQAYLWGEDIPNTTLPQAIAKPLTEVSTLLEIKPFATFAAFCLWSFSVHFDDDIGGDCHKFLDNMSMTCSFTGTTDEAWFFNVSTAIEARGGRIIPSILNAISAVQNNDMLTVEGFLLDFTICLRDLCDLIDRMHENCRPSVFYHRIRPFLSGTSNNNPATENSKGVFYVQAEDGTGEWHRYSGGSNAQSSLIQLFDITLGINHDIGYKTRYLREMRSYMPAQHRRFLARMEEISNLRPYALSHGPGSSNMCSLYNSAVLGLKNLRDKHMALVFRYIIIPRAKEKAGNGLAIRQKDLVGTGGTDMIPFLRETRDDTMNAVHLPYS
What is the function of this protein?
Indoleamine 2,3-dioxygenase; part of the gene cluster that mediates the biosynthesis of the benzazepine alkaloid nanangelenin A which contains an unprecedented 3,4-dihydro-1-benzazepine-2,5-dione-N-prenyl-N-acetoxy-anthranilamide scaffold (PubMed:32182055).  The first step of nanangelenin biosynthesis is catalyzed by the indoleamine 2,3-dioxygenase nanC which produces N-formyl-kynurenine through the catabolism of tryptophan (PubMed:32182055).  The two-module NRPS nanA then utilizes anthranilate (Ant) and L-kynurenine (L-Kyn) to assemble the dipeptide product nanangelenin B (PubMed:32182055).  The first adenylation domain of nanA (A1) loads anthranilate onto the T1 domain, while A2 loads kynurenine, generated through spontaneous nonenzymatic deformylation of the nanC-supplied N-formyl-kynurenine (PubMed:32182055).  The peptide bond formation between the tethered amino acids is catalyzed by the first condensation domain (C1) between anthranilate's carbonyl carbon and kynurenine's aliphatic primary amine (PubMed:32182055).  The second C domain (C2) catalyzes the final cyclization event between the aromatic amine of kynurenine and the tethered carbonyl carbon, yielding nanangelenin B (PubMed:32182055).  The terminal T3 domain enhances the catalytic efficiency of C2, suggesting the T2-tethered Ant-L-Kyn is transferred to T3 prior to cyclization by C2 (PubMed:32182055).  Once released from nanA, nanangelenin B is then prenylated by the prenyltransferase nanD to form nanangelenin C (PubMed:32182055).  Nanangelenin C is then N-hydroxylated by the FAD-dependent monooxygenase nanF and further acetylated by the acetyltransferase nanB to yield nanangelenin F (PubMed:32182055).  Finally, the N-methyltransferase nanE methylates the amide nitrogen of 1-benzazepine to convert nanangelenin F into nanangelenin A (PubMed:32182055).  NanE is also able to methylate most of the intermediates of the pathway such as nanangelenin B and nanangelenin C to produce nanangelenin D and nanangelenin E, respectively (PubMed:32182055).
What are the official names of this protein?
Indoleamine 2,3-dioxygenase nanC, IDO nanC, Nanangelenin A biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the indoleamine 2,3-dioxygenase family.
Protein: RIR2_HELPJ
Sequence: MEVSRKKIYNPNSTESVNERKIFGGNPTSMFDLNKIKYQWADHLWKTMLANTWFAEEVSMNDDKRDYLKLSAEEKIGYDRALAQLIFMDSLQANNLIDNINPFITSPEINLCLVRQAYEEALHSHAYAVMVESISANTEEIYDMWRNDMQLKSKNDYIAQVYMELAKNPTEENILKALFANQILEGIYFYSGFSYFYTLARSGKMLGSAQMIRFIQRDEVTHLILFQNMINALRNERADLFTPQLINEVIEMFKKAVEIEASWGDYITQGKILGLTSSLIEQYIQFLADSRLSKVGIAKVYGVQHPIKWVESFSSFNEQRSNFFEARVSNYAKGSVSFDDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: TRIM5_MACMU
Sequence: MASGILLNVKEEVTCPICLELLTEPLSLHCGHSFCQACITANHKKSMLYKEGERSCPVCRISYQPENIQPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDYDKTNVSADFEQLREILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQYMRELISELEHRLQGSMMDLLQGVDGIIKRIENMTLKKPKTFHKNQRRVFRAPDLKGMLDMFRELTDARRYWVDVTLAPNNISHAVIAEDKRQVSSRNPQIMYQAPGTLFTFPSLTNFNYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQSDAMYNIEQNENYQPKYGYWVIGLQEGVKYSVFQDGSSHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Restricts infection by human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV-agm).  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2 (PubMed:25127057).  Also plays a role in autophagy by acting as a selective autophagy receptor which recognizes and targets HIV-1 capsid protein p24 for autophagic destruction (PubMed:25127057).
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies (PubMed:20357094, PubMed:22078707). Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27 (PubMed:17156811). In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1 (PubMed:20357094).
Protein: EF1A2_EUPCR
Sequence: MERKEKDHLNLVVIGHVDSGKSTTTGHLIYKLGGIDERTLAKLEEKALELNKASFKYAFVLDNLKAEQERGITINCALRQFDTPSRSYTIIDAPGHKDFIKNMITGTSQADAAVLIIAAKKGEFEDGFSREGSTKDHALLAYTMGIKQAIVAINKMDTIDYDEERFNEIVENVSDHLGKIGYKKENVKYIPISGFDGDNMLEQSENLPWYKGPTLTEALDEFKVPKRPIKKPLRVPIQDVYKIAGIGTVPVGRVETGVLKRGMEVQFTTGATSEVKSLEAHHNKLEEAEPGLNVGFNVRLEAKEIKAGHVCGDAKNDPPKNAESFIAQVIVMNHPGHIKAGYQPVLDIHTAHVATKFKTLLSKNEARTGKLIEEAPKFLKNGESGIVELVPTKPLCVEEFSKYAALGRFVIRDMKRTVAVGVIQEVIHKKETKKKASKR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 2, EF-1-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_AQUAE
Sequence: MSEYLKALFELKELRQKFIFTLLMFVIYRLGSHIPIPGINPEALRDFLKAFEGSVFALYDIFSGGNLGRLTVFALGVMPYISASIMMQLLTVAIPSLQRLAKEEGDYGRYKINEYTKYLTLFVATVQSLGIAFWIRGQVSPKGIPVVENPGISFILITVLTLVAGTMFLVWIADRITEKGIGNGASLIIFAGIVANFPNAVIQFYEKVKTGDIGPLTLLLIIALIIAIIVGIVYVQEAERRIPIQYPGRQVGRQLYAGRKTYLPIKINPAGVIPIIFAQALLLIPSTLLNFVQNPFIKVIADMFQPGAIFYNFLYVTFIVFFTYFYTAVLINPVELAENLHKAGAFIPGVRPGQDTVKYLERIINRLIFFGALFLSVIALIPILISVWFNIPFYFGGTTALIVVGVALDTFRQIETYLIQKKYKSYVRR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently (By similarity).
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_BARQU
Sequence: MTQNTFFPIFPHQHLLGIKDLNVQDLIVLLDRANANIPFSKKIDKKQSPLHGCTQINLFFEASTRTQSSFELAGKRLGADVMSMPIGNSSVKKGETLIDTATTLNAMKPDILVIRHSCAGAAALLAQKVDCCIINAGDGAHEHPTQALLDALTIKRAKGRIEGLTVVICGDILHSRVARSNILSLNALGARVRAVAPSTLLPAGIADMGVEVYNTMKEGLKGADVIMMLRLQRERMTDSFIPSIREYFHYFGLHKENLSYAKSDCIILHPGPINRGIEIASDIADGPQSMIHTQVEMGIAVRMAVMEALLDSRLKASGEKK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ILVD_NOCSJ
Sequence: MTEPTSRPDIKPRSRDVTDGLEKAAARGMLRAVGMGDEDFAKPQIGVGSSWNEITPCNLSLDRLAKAVKNGVHAAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMMAERLDGSVLLAGCDKSLPGMMMAAARLDLASVFLYAGSTMPGQVDGNDVTIIDAFEAVGACLAGKISRDEVDRIERAICPGEGACGGMYTANTMASIAEAIGMSLPGSAAPPAVDRRRDGFAHRSGEAVVNLLRQGITARQIMTRAAFENAITVAMALGGSTNAVLHLLAMAREADVDLTIDDFNRIGDKVPHLGDLKPFGKYVMNDVDKIGGIPVVMKALLDAGLMHGDALTVTGKTLAENLAELAPPELDDEVIRKLDRPIHKTGGLTILKGSLAPEGAVVKTAGFDDSVFTGTARVFDGERAAMDALEAGQIQPRDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLITDGRFSGGTTGLCVGHIAPEAVDGGPIAFVRDGDQITLDVANRLLEVEVVGPDAEAEWERRKVGWEPNPPKYTRGVLGKYAKIVQSAAHGAITG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS5_ECO57
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y1710_HAEIN
Sequence: MKGQLNLRSETTALSLKQGEVAFITAGAAYEVEGLIEGYAVVAKLP
What are the official names of this protein?
Uncharacterized protein HI_1710.
Protein: ISPF_XANCP
Sequence: MSFNFRIGQGYDVHAFGPGDHLMLGGVRMAHSHGVLAHSDGDVVLHALCDAMLGGLALGDIGVHFPPSDARWKGADSAQFVQHCDQLLRDRGWRVGNADITVICERPKVGPHALAMRERIAGLLAIELDAVSVKATTSEKLGFTGRSEGIAAQAAVLLGKIAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TATA_BART1
Sequence: MGNIFSPTHLIIILLLILLLFGRGRVAELMGDVAKGIKAFKKNMKEEEESIEDKVEMADTSQVINEESQQSQPLSVKRAAIRRKASSDSKGGKASIAKKQRVK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SELP_SV40
Sequence: MQRPRPPRPLSYSRSSEEAFLEA
What is the function of this protein?
May play a role in the lytic cycle.
What are the official names of this protein?
SV40 early leader protein, SELP.
What is the protein family that this protein belongs to?
Belongs to the polyomavirus early leader protein family.
Protein: PNCB_ACIAD
Sequence: MLSMSPIIHSLLDTDLYKFTMLQVVLHQFPQTHSVYHFRCRNLDETQYPLTDILDDLNEQLDHLCTLKFKDDELQYLRSFRFIKSDFVDYLELFQLKRRFITAGIDEEGRLDIWVEGPMVQAMMFEIFVLAIVNELYFRRIRSDAVLEEGERRLQAKLALLEQYQTQHQSDEPPFLVSDFGTRRRYSFEWQKHVIAAFHHHFPNIFRGTSNVLLAKELNITPIGTMAHEFLQAFQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLEKAWELHQYFKGRFKVSFGIGTNLTNDMGQTPLNIVLKLVECNGQSVAKISDSPGKTMTDNDTFLAYLRQVFQIAEEEPVA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (PubMed:20926389).  Functions in the deamidating salvage pathway for production of NAD from nicotinamide (PubMed:20926389).  Displays a strict preference for nicotinate over nicotinamide substrate (PubMed:20926389).
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: TPGD2_POGCB
Sequence: MELKNQSVAIISSNASRPLAHYHPDVWGDRFLLYKPNPSSEAGQKPVIEELKQQVRSELKEASNDYMRQLKMVDAIQRLGIESLFEEDIDNALKNLSENFDDYCKDKHDLYAIALSFRLLRQHGYRISCDVFDKLKDGEDGFKVPPSDEALAVVELLEATHLRIHGEVVLDRAFVFARIHLESIEANLNNPVAKQVHNALYGYSNRRGMQQVEARKYIPIYEQYASHHQGLLKLATLNFNLQQTMHKRELSELSRWYRDLEVPTMLPFARQRLVETYFWDAGVVFEPENDVARMILVKVQCLISFLDDTFDAYGSFEELQLFTDAINTWDVSCLDQLPDYMKIIYKALLGVFEVIEKLMIKQGTLYRLNYAKEAMKIVVGGYFVEAKWREEKSKPTTQEYMQVATKSAGYMTLIITSFLGMEANIATKEAFDWVLSEPDVMKAAITLARLTNDIVGIELEKERKHIATAVEVYEDEHKLSMQEAMVEIKNQIESGWKTINEAFLRPTKFPTPILYRILNYCRVLEVIYDKSDRYTHVDPALQDIIKQLYIHPIP
What is the function of this protein?
Sesquiterpene synthase involved in germacrene D biosynthesis.
What are the official names of this protein?
Germacrene D synthase 2, PatTpsBF2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RLMH_PARDP
Sequence: MRMVIAAVGRLRQGPEAKLIADYLDRHAKAGRALGLPPVTLAEVEDKRGGGMVAEAALLARAIPQGAALVVLDERGQMLSSPEFAARIAGWRDQARDVAFVIGGADGIDPGLRDGADLAISFGRMVWPHMLVRVMLAEQIYRATTILAGNPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPI1_ASHGO
Sequence: MSSNNQESLANRSHTVTVSETSQILQLRANQTEQVPKLAKKEQKSKVRWDENVVDNEHMNKKKTKICCIFHPQQNFDDEDGGECEHASSSASSSSSSESENDTSMDFEARRQARIARRRQKLERKRSSSPNAYEYQPDYSQYRQKYLHGDK
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYLC_PSEPU
Sequence: MRETKEQPIWYGKVFSSNWVEARGGVANVVDPSNGDILGITGVANGEDVDAAVNAAKRAQKEWAAIPFSERAAIVRKAAEKLKEREYEFADWNVRECGAIRPKGLWEAGIAYEQMHQAAGLASLPNGTLFPSAVPGRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALIAEIFSDAGMPDGVLHVLPGGADVGESMVANSGINMISFTGSTQVGRLIGEKCGRMLKKVALELGGNNVHIVLPDADLEGAVSCAAWGTFLHQGQVCMAAGRHLVHRDVAQQYAEKLALRAKNLVVGDPNSDQVHLGPLINEKQVVRVHALVESAQRAGAQVLAGGTYQDRYYQATVIMDVKPEMEVFKSEIFGPVAPITVFDSIEEAIELANCSEYGLAASIHTRALATGLDIAKRLNTGMVHINDQPINCEPHVPFGGMGASGSGGRFGGPASIEEFTQSQWISMVEKPANYPF
What are the official names of this protein?
Benzaldehyde dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: MOAC_XANAC
Sequence: MPANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHELIPFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRDIGAAQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: UCRI_RAT
Sequence: MLSVAARSGPFAPVLSATSRGVAGALRPLLQSAVPATSEPPVLDVKRPFLCRESLSGQAATRPLVATVGLNVPASVRYSHTDIKVPDFSDYRRAEVLDSTKSSKESSEARKGFSYLVTATTTVGVAYAAKNAVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDPQHDLERVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPTYEFTSGDVVVVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS) (By similarity).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Liver regeneration-related protein LRRGT00195, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLNB2_METMI
Sequence: MKEIIAIIRPSKMAQTKTVLEGLGFPAMTANRVLGRGKQKAIVGELGFEVDNKELLNQPGDMRYIPKTMLTLIVPDEDASLVVEAIMKVNKSGQYGDGKIFVCPIEDIITVRTSERGEAAI
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen fixation nifHD region glnB-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: LRK16_ARATH
Sequence: MAQGLHLIWVIFCLHLICISSQQETEFIFNGFGQADLYTDGVAKILPNGLLQLTDGSGQKMGHAFFKKPFEFKSPRSFSFSTHFVCALVPKPGFIGGHGIAFVLSASMDLTQADATQFLGLFNISTQGSPSSHLVAVELDTALSAEFDDIDANHVGIDVNSLMSIASTPAAYFSEIDGENKSIKLLSGDPIQVWVDYGGNVLNVTLAPLKIQKPSRPLLSRSINLSETFPDRKFFLGFSGATGTLISYQYILGWSLSRNKVSLQTLDVTKLPRVPRHRAKNKGPSVVLIVLLILLAIIVFLALGAAYVYRRRKYAEIREEWEKEYGPHRFSYKDLYIATNGFNKDGLLGKGGFGKVYKGTLPSKGQIAVKRVSHDAEEGMKQFVAEIVSMGNLKHKNMVPLLGYCRRKGELLLVSEYMPNGSLDQYLFNDEKPPFSWRRRLLIIKDIATALNYMHTGAPQVVLHRDIKASNVMLDTEFNGRLGDFGMARFHDHGKDPATTAAVGTIGYMAPELATVGACTATDVYGFGAFLLEVTCGRRPVEPGLSAERWYIVKWVCECWKMASLLGARDPRMRGEISAEEVEMVLKLGLLCTNGVPDLRPSMEDIVQYLNGSLELPDISPNSPGIGSFTPLIIGSNPPVSPSTKTFYTSSSANDSTFVTHSIIHGDGR
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase I.6, LecRK-I.6.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PYRB_ACIAD
Sequence: MHLAALHTPSQIQLNQQGNLKHFLTIEGLSKETLTKILDTAQSFINDQNQLITTPLLEGRTVMNLFFENSTRTRTTFEAAAKRLSANVLNIDIARSSTSKGETLRDTLWNLEAMAADIFVVRHSSSGAAHFIAKDVCPHVAIINAGDGRHAHPTQAMLDMLTIRRETKKPFEELSVAIIGDIKHSRVARSNIAALQTLGCNDIRVIAPNTLLPVGFKEYGDHVRLFNKMDDGVKDCDVIIALRIQNERIDSPALSSQAEFYRMYGLNQERLALAKPDCIVMHPGPMNRGVEIDSSIADGPQSVILHQVTNGIAVRMAVLALSMQGQLQEQGLIEAIAV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: LEUC_BRUMB
Sequence: MSAPRTLYDKIWDDHVVDQQEDGTCLLYIDRHLVHEVTSPQAFEGLHMAGRPVRHPEKTLAVVDHNVPTSPDRINGIQNEESRIQVEALARNAADFGVEYYSERDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGKLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAPDETTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGSSPEDVVSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRIEDLRAAAKVVEGKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIEAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIRAWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: BGBP_HYPCU
Sequence: RCARVCAVLFLFIQISYGQYQVPQVTVQALKPRGFKASIPDSPSVSLFVFQGNINRAISKSDIGTISGEILKAKDGRWTFEDPNVELKVGDVVNYYVVVVSNRGGYIKDNLSFTVSALEDPSSTGTGTDPVPTPTTCRPTATKLRSGVACAGQTIFEENFNTFREDVWQIEQYIPVYSTEFPFVSYQHLSQDPTVAVTGGNLRITPKLQQRMPGFTDSSIYSGSLNIFSGCTAPAEACMKDAWGASILPPVVSGRITSKAFAFTYGTVFVKAKLPQGDWIYPEILLEPFLKKYGSTHYSSGVIKIASARGNRELTSGYTDYSNKMLFGGPVMNLQCYDTLLESKASSNGRQWGDDFHEYVLRWAPERITLSVDGVEWARVEPTASGLSGRFPQTCSKLPRTFLAAGTKMAPFDDHFYLTLGVAAGSITEFPDGVQTSGSRPKPWTNTGSKAMLHFWEDMDSWFATWNQPQLLVDYVKVVAL
What is the function of this protein?
Involved in the recognition of invading microorganisms.  Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity).
What are the official names of this protein?
Beta-1,3-glucan-binding protein, BGBP, Beta-1,3-glucan recognition protein, BetaGRP, Gram negative bacteria-binding protein.
What is the protein family that this protein belongs to?
Belongs to the insect beta-1,3-glucan binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_ORITI
Sequence: MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVSISNTGIKKLYAYIRILAACITGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEHEVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.