PharMolix/UniProtQA huggingface dataset:
Protein: DEGS1_PONAB
Sequence: MGNRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLAAFYIVKDLDWKWVIFGAYAFGSCINHSMTLGIHEIAHNAAFGNCKAMWNRWFGMFANLPIGIPYSVSFKSYHMDHHRYLGADGVDVDIPTDFEGWFFCTAFRKFIWVILQPLFYAFRPLFINPKPITYLEVINTVAQVTFDILIYYFLGIKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLVRKIAAEYYDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE
What is the function of this protein?
Has sphingolipid-delta-4-desaturase activity.  Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity).  Catalyzes the equilibrium isomerization of retinols (By similarity).
What are the official names of this protein?
Sphingolipid delta(4)-desaturase DES1, Degenerative spermatocyte homolog 1, Dihydroceramide desaturase-1, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Mitochondrion membrane. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSXE_ECOL6
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAVAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MAGT1_PONAB
Sequence: MAAGWWFWCVSVTVAVALLIVCDVPSVSAQRKKEMVLSEKVCQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS
What is the function of this protein?
May be involved in Mg(2+) transport in epithelial cells.
What are the official names of this protein?
Magnesium transporter protein 1, MagT1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1, Oligosaccharyl transferase subunit MAGT1, Implantation-associated protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the OST3/OST6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRHO_YERPS
Sequence: MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTLEDAKTFRDNLYSQFVKLGVFGRVYVAKEGINAQISVPANRYDEFKIALFASHPALDQVRLNVAHEDDGKSFWVLRLKVRERIVADGIDDDSFDPANIGHYLKADQVNQMIDDPDTLFVDMRNHYEYEVGHFENAIEVPSDTFREQLPMAVDMLQHDKEKNIVMYCTGGIRCEKASAYMLHNGFKNVYHVEGGIIEYARKAKEQGLPLKFIGKNFVFDERMGERISDDVIAHCHQCGTPCDAHTNCKNDGCHLLFIQCPVCAAKFEGCCSQICQEELKLPQEEQRSRRAGRENGIKIFNKSKGLLQATMHIPSPEKSADEK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ACPS_STRA3
Sequence: MIVGHGIDLQEIEAITKAYERNQRFAERVLTEQELLLFKGISNPKRQMSFLTGRWAAKEAYSKALGTGIGKVNFHDIEILSDDKGAPLITKEPFNGKSFVSISHSGNYAQASVILEEEK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_PSEF5
Sequence: MATVDRWLLPDGIEEVLPPEAARIEVARRQVLDLFQSWGYEFVVTPHIEYLESLLTGAGQDLDLRTFKVIDPQSGRQMGFRADITPQVARIDAHTLRREGPSRLCYAGSVLHAQPRALSSSRSPIQLGAELYGDASPSSDVEVISLMLAMLQLADVPDVHMDLGHVGIYRGLAQAAGLSGAVEQQLFDALQRKAIDEVISLTEGLPADLADMLRSLVDLCGSREVLGDARRRLAGAPTSVLLALDELLTIAERLSVRFPDLPLYFDLGELRGYHYHTGVVFAVFVPGVGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGRAEVELPSGGIWMPDNTDAALWQTVCRLRSEGQRVVQALPGQPLAAAREADCDRQLIQQNGLWQVLPLAS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_WIGBR
Sequence: MVNFEKNINELQEKLISVNRVSKTVKGGRIFSFTALTVVGDCQGKIGFGYGKSKEVPLAIQKAMDKARKNMIIIPIVCKTLQHEINGYHTGSRVFMKPASEGTGIIAGGAMRAVLEVAGVHNVLAKVYGSTNPINVVRATVNALKKMRFPMHIAEKRGKSIDDILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL16_MYCGI
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTSVSFGDYGIQAMGHAYITNRQIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPDEKIAREALTRAIHKLPIKARIVTREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: APL3_LOCMI
Sequence: MNTLLAVLMLAVAAQARPDAAGHVNIAEAVQQLNHTIVNAAHELHETLGLPTPDEALNLLTEQANAFKTKIAEVTTSLKQEAEKHQGSVAEQLNRFARNLNNSIHDAATSAQPADQLNSLQSALTNVGHQWQTSQPRPSVAQEAWAPVQSALQEAAEKTKEAAANLQNSIQSAVQKPAN
What is the function of this protein?
Assists in the loading of diacylglycerol, generated from triacylglycerol stores in the fat body through the action of adipokinetic hormone, into lipophorin, the hemolymph lipoprotein.  It increases the lipid carrying capacity of lipophorin by covering the expanding hydrophobic surface resulting from diacylglycerol uptake.  It thus plays a critical role in the transport of lipids during flight in several species of insects.
What are the official names of this protein?
Apolipophorin-3b, Apolipophorin-IIIb, ApoLp-IIIb.
What is the protein family that this protein belongs to?
Belongs to the insect apolipophorin-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VITH3_ORYSJ
Sequence: MAMQMNSVVHVSTSPSPSPATSPPPEGKQEHGEVAAVHVVGVGDDEAVMVVKDEEAFGGGGVDYSGRAQWLRAAVLGANDGLVSVASLMIGVGAVSESGRAMLVSGVAGLVAGACSMAIGEFVSVYAQYDIEVAAARRRRRQRRRRCDGDGEEEGSGRLPSPFKAAAASALAFTVGALLPLLAGGFVRPWAPRVAAVCAATSAALAGFGALGAALGGASPARSAARVLLGGWAAMAACYGVLRLFANLY
What is the function of this protein?
Probable vacuolar iron transporter that may be involved in the regulation of iron distribution throughout the plant.
What are the official names of this protein?
Vacuolar iron transporter homolog 3, Protein NODULIN-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the CCC1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RUVA_CLOB1
Sequence: MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGVYGFLTKDELSMFKLLLTINGVGAKAALSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKTAQRIILELKDKIEIDILEEDDEQIINKVADDKKVLEAVAALVTLGYSEKEANKVINSCDKNNSLEQIIKEALKYLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ALL4_ASPFU
Sequence: MQLKNSMLLLTALAAGSSVARLHGHERRHLHHAGEKREVGDTVYATINGVLVSWINEWSGEAKTSDAPVSQATPVSNAVAAAAAASTPEPSSSHSDSSSSSGVSADWTNTPAEGEYCTDGFGGRTEPSGSGIFYKGNVGKPWGSNIIEVSPENAKKYKHVAQFVGSDTDPWTVVFWNKIGPDGGLTGWYGNSALTLHLEAGETKYVAFDENSQGAWGAAKGDELPKDQFGGYSCTWGEFDFDSKINQGWSGWDVSAIQAENAHHEVQGMKICNHAGELCSIISHGLSKVIDAYTADLAGVDGIGGKVVPGPTRLVVNLDYKE
What are the official names of this protein?
Allergen Asp f 4.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_PEDPA
Sequence: MAKLTVSDLDVKNKKVLMRVDFNVPVKNGVIGDDNRVVAALPTIKYIIENGGKAILFSHLGRIKTEEDKKELTLRPVAQRLSDLLGKPVTFVPVTRGAQLEDAVNGMNDGDVLLFENTRFEDLDGKKESKNDPELGKYWASLGDMFVNDAFGTAHRAHASNVGVAEAMKADGKQVAAGFLMEKEIKFLGEAVDEPKHPFVAILGGAKVSDKIGVIDHLLNKADKVIIGGGMTYTFYAAKGMSIGNSLVEADKIDVAKEILAKGGDKIVLPSDSIVAEKFDNDVPNKVVEGDIPDGYMALDIGPKSVAEFKDVLKDAKTVVWNGPMGVFEMSNYANGTLEVGKFLGTLSDATTIVGGGDSTAAVKQLGVGDQLTHISTGGGASLEYLEGKELPGIAAISNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC2_ARCFU
Sequence: MGKTIAEKILSEKSKSDAYAGDIVVAEIDQIALQDGTAPLAIRQLMELGTEVRAADRTHFFVDHAAPSPRRELSNDQKFIYEFAKKVGADFNPPGEGIIHQIMVERYVKPGDLAVGADSHTCTYGGIGAFSTGMGSTDVAVAIALGKNWFRVPESFRVQLDGSLPKGVFAKDVILKLIGDLGVDGATYKALEFHGECAENMTVEERLTIANMAVECGAKAGIFESDENTRKFLAELGREGDFREVKADEDAEYEKEIYMDVSSLVPVVSKPHNVDNVAEISEVEGTEVNQVYIGTCTNGRLSDLEVAARILKGRKVKEGVRLIVVPASRRVYLQALDKGLIRVFVEAGGMVLNPGCGPCVGIHQGILADGEVCISTQNRNFKGRMGNPNAEIFLASPATAAASAVKGYIADPREFL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RK21_SPIOL
Sequence: MASATLAFSCSSLCATLKLPQNLNPLLLNVPPLSKPFSGVVSPPSLSRLSLLPVAAKRRRFQEIPEELKAEFEEFQRPPNQKPQLSDVLPDDFQAPEPGTPEYNDIINQFLPKKGPPPPREEIFAVVVIGSRQYIVIPGRWIYTQRLKGATVNDKIVLNKVLLVGTKASTYIGTPIVTNAAVHAVVEEQLLDDKVIVFKYKKKKNYRRNIGHRQPITRIKITGITGYEDYPASTLEAEVEAKEEAEAEAEAEAVPV
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L21, chloroplastic, CL21, CS-L7, Chloroplastic large ribosomal subunit protein bL21c.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: XERD_RALSO
Sequence: MTQAAPETLPLPPSSTEAIQRFCDALWLEDGLARNTLDAYRRDLTLYAQWLAGRGKALDQTEDVDLSDYFAARHEDSLASTANRRRTVFKRFFQWALREHLVSADPTRLLSTAKQPPRVPKTLSEAQVEALIAAPDVDAPLGLRDRAMIELMYASGLRVSEIVALKTVEVGLNEGVVRVIGGKGGKDRLVPFGAEAGDWLRRYLRDGRTALLGERTADALFVTARGDGMTRQAFWYLIKRYAQRADIHAPLSPHTLRHAFATHLLNHGADLRVVQMLLGHADISTTQIYTHVARERLRTLHAQHHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF97_ARATH
Sequence: MGSLRVSTFAVAVVVCLSILLMSPTDGRRVCDSAAGLCSMLFSCNTQCNSLGRNFTGGECSDARFPGLSVCYCCHNVESSAEMESM
What are the official names of this protein?
Defensin-like protein 97, Low-molecular-weight cysteine-rich protein 85, Protein LCR85.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOBA_METJA
Sequence: MVTIIAGIILSGGKGERIGGKKPFRVFNGKYLINYPSDILKSLNIPFVTVFAKNSIDLEMEKEYLTKYKCLISFDLIEGKGPLMGILCGMRVLNAKWFVVLPCDCPYINKEALKKLISNISIAEKNNNLCIIPKHENGYIEPLFALYKRDALSILNKIIMEDKNLSIRYFISYLNPLYIKAEELDESKRIFKNINTIEELMDNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DX39B_RAT
Sequence: MAENDVDNELLDYEDDEVETAAGADGTEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
What is the function of this protein?
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint.  Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity.  Even with the stimulation of RNA, the ATPase activity is weak.  Can only hydrolyze ATP but not other NTPs.  The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA.  However, ssRNA stimulates the ATPase activity much more strongly than dsRNA.  Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro.  The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly with [] reporting a stimulatory effect.
What are the official names of this protein?
Spliceosome RNA helicase Ddx39b, 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, DEAD box protein Uap56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: TAP26_BOVIN
Sequence: MAPVWPAARGRTGGLGTRGRVSPVEFRNKNVKRKTWRPNHLQAFAGSVREGQGFAFRRKLKIQQTYKKLLRREKKSQTPSESPFTDWYPDHLKHLYLAEEERLKKQLRKADQPLSEEQVDQPLPEDQGSSDQALSEERCSIEQPQPAEPCSIRINSINIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRLYKKKKMEVFKILSKKTKKGQPNLNLQMEYLLKKIQENN
What is the function of this protein?
Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC).  Enhances homeobox protein Nkx-2. 1-activated SFTPB and SFTPC promoter activities (By similarity).
What are the official names of this protein?
Thyroid transcription factor 1-associated protein 26, TTF-1-associated protein 26, Coiled-coil domain-containing protein 59.
What is the protein family that this protein belongs to?
Belongs to the TAP26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRO_ADEF1
Sequence: MGTSGADLENIVLSLGLHSGFLGIFDKHFPGFLNVNKPSFAIVNTGDIIQGGLHWIAFAFDNVTSTFFMFDPFGWSDMELYRKYEFQYHRILKSTALTKPSRCIKLVKSKEAVQCTCSAACGLFCCLFLASFYHYPTFPMRGNPIIDLVDGIPPTKLHSSYGIYLTHCNQKKLIAWLLSNSAYFRKNAMLMIHNTRLYYLYTHL
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: HSPQ_ECODH
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_HERAR
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERVLFYTGVNHKLGETHEGSATTDWMEQEQERGITITSAAVTCFWKGMANNLPAHHINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYEQMRARLKANPVPIQVPIGAEDQFFGVVDLIKMKSIIWDEASQGMKFEYGEIPANLLAEAQKWRENMVEAAAEASEELMNKYLEEGDLSEAEIKAALRTRTIANEIVPMMCGTAFKNKGVQAMLDAVIDYLPSPIDIPPVPGLNESDEPIVRKAEDGEKFSALAFKIATDPFVGQLCFIRCYSGTLNSGDTVLNSVKEKKERIGRIVQMQANQREEIKEMRAGDIAAVVGLKDTTTGDTLCDDKAFVVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAAEDPSFRVRTDEESGQTIIAGMGELHLDIIVDRMKREFNVEATVGKPQVAYRETIRKTCEEIEGKFVKQSGGRGQYGHVVLKIEPQEPGKGFEFVDAIKGGTVPREYIPAVEKGVRETLTSGVLAGYPVVDVKVTLFFGSYHDVDSNENAFRMAASMAFKDGCRKASPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMDEIAGGGGKIIKAEVPLSEMFGYATSLRSATQGRATYSMEFKHYSEAPKNVIDAIVTSKAPK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_SALPB
Sequence: MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DRP35_STAEQ
Sequence: MANQKLPTLKYTGKSESAVPIVSESELQTVTAEPWVKISDKGLQLEGLNFNREGQLFLLDVFEGNIFKVNPATKEVTTKFQSVKDNPAAIKVHKDGRLFICYLGDFKTTGGIFATTEKGEQIEEIISDLNTEYCIDDMVFDSKGGFYFTDFRGYSTQPLGGVYYVDPDFKTVTPIIQNISVANGIALSTDEKVLWVTETTTNRLHRIALEDDGVTIAPFGATIPYYFTGHEGPDSCCIDSNDNLYVAMYGQGRVLVFNKRGYPIGQILMPGRDDGKMLRTTHPQFIPGTNQLIICTNDIENHSEGGSMLYTVNGFAKGYESYQFQ
What is the function of this protein?
Exhibits lactonase activity.  Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis (By similarity).
What are the official names of this protein?
Lactonase drp35.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLD10_HUMAN
Sequence: MSAAQGWDRNRRRGGGAAGAGGGGSGAGGGSGGSGGRGTGQLNRFVQLSGRPHLPGKKKIRWDPVRRRFIQSCPIIRIPNRFLRGHRPPPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLVLHGNNLLVFGGTGIPFGESNGNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPEERYRHEIAHDGQRIYILGGGTSWTAYSLNKIHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPATMPEPVYFHCAAVTPAGCMYIHGGVVNIHENKRTGSLFKIWLVVPSLLELAWEKLLAAFPNLANLSRTQLLHLGLTQGLIERLK
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948).  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms (PubMed:29779948).  The CRL2(KLHDC10) complex specifically recognizes proteins with a proline-glycine (Pro-Gly) at the C-terminus, leading to their ubiquitination and degradation (PubMed:29779948).  Participates in the oxidative stress-induced cell death through MAP3K5 activation (PubMed:23102700).  Inhibits PPP5C phosphatase activity on MAP3K5 (PubMed:23102700).  Acts as a regulator of necroptosis (By similarity).
What are the official names of this protein?
Kelch domain-containing protein 10.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EDL15_ARATH
Sequence: MAEEGLLLPASSTSSSSSLLSEISNACTRPFVLAFIVGSCGAFAFGCIIGYSAPTQTSIMKDLNLSIADYSLFGSILTVGLILGALICGKLTDLVGRVKTIWITNILFVIGWFAIAFAKGVWLLDLGRLLQGISIGISVYLGPVYITEIAPRNLRGAASSFAQLFAGVGISVFYALGTIVAWRNLAILGCIPSLMVLPLLFFIPESPRWLAKVGREMEVEAVLLSLRGEKSDVSDEAAEILEYTEHVKQQQDIDDRGFFKLFQRKYAFSLTIGVVLIALPQLGGLNGYSFYTDSIFISTGVSSDFGFISTSVVQMFGGILGTVLVDVSGRRTLLLVSQAGMFLGCLTTAISFFLKENHCWETGTPVLALFSVMVYFGSYGSGMGSIPWIIASEIYPVDVKGAAGTMCNLVSSISAWLVAYSFSYLLQWSSTGTFLMFATVAGLGFVFIAKLVPETKGKSLEEIQSLFTDSPPQDSTIF
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Sugar transporter ERD6-like 15.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL9_ALIF1
Sequence: MQVILLDKIGNLGSLGDQVNVKAGYARNFLIPQGKAVMATKANVEMFETRRAELEANVAKQLAAAEARAEKVNALEVTIASKSGDEGKLFGSIGTRDIAEAATAAGVEIAKSEVRLPEGALRTTGSFEVSIQLHSEVFATLKLEVVAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.