PharMolix/UniProtQA huggingface dataset:
Protein: YQZC_BACSU
Sequence: MTKRGIQAFAGGIILATAVLAAVFYLTDEDQAAAVKDNKTVTEQDVNNYLDSKKLVSVNRDEYQKLLDSKEKSLNNDSGSDTKSDKVKTYKLTIKDGMSTADVSAILEKEGIISSAQDFNDYVIDAGYHKEIRAGEFKVKSDMSFKKIVKTLTR
What are the official names of this protein?
Uncharacterized protein YqzC.
Protein: I2B7_CONPO
Sequence: MMFRLTSVGCFLLVIVLLNVAVLTNASCRNEGAMCSFGFQCCKKECCMSHCTDFCRNPDKRAHGHGLLRFWGQR
What are the official names of this protein?
Conotoxin Vt11.7, Conotoxin Vi11.7.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RD2_PHYMI
Sequence: MRLSYVFVVFAASLLVTADTLSTNTGVQAANLVGPAQRLLRKHYTAAENDGDSEARALNPEKMKTMWKAGMTVDGYAAKLKLTDKIAAAANSAKAMEKLGETHKMKKLLRYLNYVAEHTAV
What is the function of this protein?
Secreted effector involved in P. mirabilis colonization of host plants (Probable).  May perturb the signaling of cell death associated with plant immunity, via interaction with a host MAP kinase (Probable).
What are the official names of this protein?
RxLR effector protein PexRD2.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: TAL2_SHISS
Sequence: MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQYAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHPN1_MOUSE
Sequence: MILEERPDGQGTGEESSRPQDDGSIRKGYGSFVQNQPGQLQSHRARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSTSVDVDQPEGEGITIPMIPLGLKETKELDWATPLKELISEHFGEDGTSFETEIQELEDLRQATRTPSRDEAGLDLLAAYYSQLCFLDARFFSPSRSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTNHAAEAFQRAAGAFRLLRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDQLQLAQEAAQVATEYGLVHRAMAQPPVRDYLPASWTNLAHVKAEHFCALAHYHAAMALCESHPAKGELARQEHVFQPSTPHEPLGPTLPQHPEDRRKLAKAHLKRAILGQEEALRLHTLCRVLRKVDLLQVVVTQALRRSLAKYSQLEREDDFFEATEAPDIQPKTHQTPEGPLSVFSTKNRWQLVGPVHMTRGEGSFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVVSLLPSPEPRGTGPRRAALLWNQRECGFETPMPTRTRPWPILGWSRKNKQGKTGSHPDPCTNRNCVTCP
What is the function of this protein?
Has no enzymatic activity.  May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.
What are the official names of this protein?
Rhophilin-1, GTP-Rho-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the RHPN family.
Protein: AROA_BACC1
Sequence: MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAFFLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAKGKTTIEDAEAVGVSYPTFFEELQKLAK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_MYCTA
Sequence: MAEPLLVVGLGNPGANYARTRHNLGFVVADLLAARLGAKFKAHKRSGAEVATGRSAGRSLVLAKPRCYMNESGRQIGPLAKFYSVAPANIIVIHDDLDLEFGRIRLKIGGGEGGHNGLRSVVAALGTKDFQRVRIGIGRPPGRKDPAAFVLENFTPAERAEVPTICEQAADATELLIEQGMEPAQNRVHAW
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNS2_MOUSE
Sequence: MKSLLLTVTLSSLVATLQTYDDLPFISEEDKLSGVWFIKATVSQRREVEGETLVAFPIKFTCPEEGTLELRHTLASKGECINVGIRLQRTEEPGQYSAFWGHTLFYIYDLPVKDHYIIYCESHPFQKISQFGYLIGKYPEENQDTLEVFKEFIQHKGFLQEKIGVPEQRDRCIPIHDSAHQDHKC
What is the function of this protein?
Transport of lipophilic molecules, possible pheromone-carrier.
What are the official names of this protein?
Vomeronasal secretory protein 2, Lipocalin-4, Vomeronasal secretory protein II, VNSP II.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_GEOSL
Sequence: MRNENTPIAVEGYPFIAIAGVLTLILAAVSWHAPVVWAGTAFFLTVTLFVAFFFRNPERITPGNENAVVAPADGVVIYLGPAREEHLGVETTKISIFMSVFNVHINRAPVSGTVLDTFYVKGKFLDVRDDRATFENEQAGLVIETARGLRLAVVQVAGLIARRIVCYAGKGDRLTRGGRYGLIRFGSRLDIYLPTTTEVKVALGEKTVAGETVLGILP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: INP1_YEAS7
Sequence: MVLSRGETKKNSVRLTAKQEKKPQSTFQTLKQSLKLSNNKKLKQDSTQHSNDTNKSVKAKKNGTSSKKTGTQRKRISTQRFSLFTYGNVQVMNSFVPIHNDIPNSSCIRRNSQVSANNVTESSGVFFNDTQSQDSQNTIKLKPTSLMAKGPIEIYQICTGFDKLKENIAPFQKSSKASSHDGHVVNYLSIGRHGDIVHPVLPKLQITRLNGAGFKYFISFYNPERYWEIEFLPLISQSQSELENSVKAFENVISKICQFSHINEGATIGNNESLSDKFKLPPTSDIEPPNTEIINNDDDDDDDDDNYDDDDLNYLLDEEYEQGCTDNSFSVISNTCSNLNASFLYPSDPTDAVSISINEAFKNAIRRTAPVLNIPIAAPSIHSKQQNKRYSSYPFIDSPPYLQDRHRRFQRRSISGLGDL
What is the function of this protein?
Required for peroxisome inheritance.
What are the official names of this protein?
Inheritance of peroxisomes protein 1.
What is the protein family that this protein belongs to?
Belongs to the INP1 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein.
Protein: TCTP_PANTR
Sequence: MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization (By similarity).  Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (By similarity).
What are the official names of this protein?
Translationally-controlled tumor protein, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
Protein: MC4R_DANRE
Sequence: MNTSHHHGLHHSFRNHSQGALPVGKPSHGDRGSASGCYEQLLISTEIFLTLGLVSLLENILVIAAIVKNKNLHSPMYFFICSLAVADLLVSVSNASETVVMALITGGNLTNRESIIKNMDNVFDSMICSSLLASIWSLLAIAVDRYITIFYALRYHNIMTQRRAGTIITCIWTFCTVSGVLFIVYSESTTVLICLISMFFTMLALMASLYVHMFLLARLHMKRIAALPGNGPIWQAANMKGAITITILLGVFVVCWAPFFLHLILMISCPRNPYCVCFMSHFNMYLILIMCNSVIDPLIYAFRSQEMRKTFKEICCCWYGLASLCV
What is the function of this protein?
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH.  Plays a central role in energy homeostasis and somatic growth.  This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
What are the official names of this protein?
Melanocortin receptor 4, MC4-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AHLLM_RHIL3
Sequence: MTDIRLYMLQSGTLKCKVHNIKMNQGNGADYEIPVPFYLITHPDGHTIIDGGNAIEVATDPRGHWGGICDVYWPVLDKDKGCVDQVKALGFDPAEVRYVVQSHLHLDHTGAIGRFPNATHIVQRAEYEYAFTPDWFAGGGYIRKDFDRPGLKWQFLNGTQDDFYDVYGDGTLTTIFSPGHAMGHQSFLVRLPSSEPLLLTIDAAYTLDHWEEKALPGFLASTVDTVRSVQKLRTIAERTGANVVTGHDPAAWSTFKKAPEYYS
What are the official names of this protein?
N-acyl homoserine lactonase AttM, AHL-lactonase AttM.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: AGLQ_HALVD
Sequence: MTSLSDILASSAEAGLSLQRSDGSMPAGHNGPYHDPETPVRNTSHWLVTFLKAHELTDENRFRQAASDAVSYLLSEEARPHGHTFEHRQNDTKDRCNGLMGQAWSLEALALAARALDNERAAAVAADVFLSHPFCDKLKLWQRVDTDGTILGFDRTFNHQLWFAASGGLVAHTAPQEVSQRVRDFLDSLPSTIDLYENGLIRHPLRPSMDLSELAESVTHDVHRSMVRNHLLHYLRPPRSKRRLRNKAEGYHSFNLYALAILAREFPSHSVWSTDLLSDILEYTLSEEFREATTDNKFSHPYNPPGFEVPAAMETFSVGSYKEREMWVNEQIQHSFDPNTSLLTRGTDDKQTHAARLYEATRLDDYEIYLD
What is the function of this protein?
Putative isomerase involved in the N-glycosylation pathway.  Required for the appearance of the methyl ester of hexuronic acid found at position four of the pentasaccharide N-linked to the S-layer glycoprotein.  Either involved in preparing the third sugar for attachment of the fourth pentasaccharide subunit or processing the fourth sugar prior to its addition to the lipid-linked trisaccharide.
What are the official names of this protein?
Archaeal glycosylation protein Q.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_BACC0
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MSBA_XYLFA
Sequence: MNVLSGAMRYATPWRTYRRLLSYAREYRWLLVVAACGALLEAVAGSTFLALMKPITNETFIERNREVALWLPLGIVGLFLLRGIAGYITDMAMGRAARSIARDFRVCVLTKYFRLPGSRFDGEPVASMLVRLGSDSEQVAHAVIDAMKVMVQQTLQVIGALVVMLWYSWTVTLAILLVAPLLAWVMQRVAKRYRRISHHIQESNAQLMQAADQALSNYQDVKVYAAQESELERYARLANINLGLAIKVESTRSLSSAAVQLLGAVGLAMLLLIAGHEALAGRLSPGDFVSLMTSMIAVIPALKQLTNVQNMLQSGIASAQRLFSVLDSPDELDTGRRPLGRARGFIEFRGITARYPGRSAPVLDSVSFVAAPGTVTAIVGRSGSGKSSLIKLIPRFYEPESGQILLDGHPLQDYLLADLRRQIALVGQQVMLFDGSIAENIAYGEMRQVVSEEIERVVVDANAQDFVNQLPEGLQFQVGVKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLVQDALQRLMPERTTLVIAHRLSTIKHADQVLVMDQGRIIESGTHVDLLARDGLYAYLYSMQFRERPT
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTNA_DICDI
Sequence: MNKLFSLILALFLVNSAVVSSLDSCSICVDFVGNSLNDLLNIILNSGVIGTCGDLCSAVPGGQIVDTVCDLLCDYVGVDEFIKLISDVDPDPIYICEKISVCKTNDNAAASLDLVQINPQNGTVGGTFTLSIAYTVTNTIATGQLAFNIIDPTGNAFGDAVLLVQQSPEQYTQQFQFQATPSEQESFPNGLYTVQALVCEGSCGSPHPNTYTLANGTTTFTISGADSSSMSGAGSFSGSSQSTQTGAASGSGSGFALF
What is the function of this protein?
Cell-counting factor that limits the maximum size of the multicellular structure.  May down-regulate the expression of gp24, which mediates cell adhesion.
What are the official names of this protein?
Countin-1.
What is the protein family that this protein belongs to?
Belongs to the countin family.
Protein: RECA_MYCGS
Sequence: RDKIGVMFGCGSWYTNVTLADGSTEKLGKIVNQKMDVEVLSYDFESGQIVPRRVTNWFNNGKAEEFLHFKVDRAGSGTGRGHASLAMTRNHLIRTPVGWREAEDINVGDRVMLAQPRLLSDQQWEIVLGSLMGDGCLSPPVRQDSESARLRIGHGAQQSAYFDWKVSLLANIPHSRTVNGKGAAFVDFSPLAELHELRSAVYLGDGKKFLSEEYLKGLTPLSLAIWYMDDGSFSLRSKGLQQRTQGGSGRIEICVEAMSEGSQVRLRDYLHDTHGLDVRLRKAGAAAKAVLVFSTAATAKFQQLVAPYMAPCMAYKLLPRFHGRSMVTPQFVEPIMELMPARVTEIESKTDYPIMSRFDIEVEGSHNYFADGVMVHNSPETTTGGKALKFYASVRMDVQRIETLKDGTNTVDNRTRVKI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2HB_MICTN
Sequence: MDKMNPAHLLVLAAVCVSLLGASSIPPQALNLNQFRLMIKCTNDRVWADFVDYGCYCVARDSNTPVDDLDRCCQAQKQCYDEAVKVHGCKPLVMFYSFECRYLASDLDCSGNNTKCRNFVCNCDRTATLCILTATYNRNNHKIDPSRCQ
What is the function of this protein?
Monomer: does not have phospholipase A2 activity but may maintain some lipid-binding character from its PLA2 lineage, which could aid in effecting neuronal depolarization.
What are the official names of this protein?
Basic phospholipase A2 homolog MitTx-beta, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_BIFAA
Sequence: MISLIIGIMVSLVVTIVGTPLLIKLVHKLNYGQYIRQDGPKSHLVKRGTPTLGGVVINLAVVLGWCSSALYRFLTRGEVPSWSAVLVLFAMLSMGFLGFIDDFAKVRKKQSEGLTVKGKFIGQFILATIYAVLALILPTKSGFPSAQAGMSFIEKPFFSFEFAGRVVAIVLFVIWVNFLMTAWTNAINLTDGLDGLAAGSSMIAFIGYAIIAFWEFYHLKGSDHPGFTYAVSDPLDLTIIAACAAVACFGFLWYNSNPASIFMGDTGSLALGGLFAAMSIATHTEFLAIILGGLFVIETMSDIIQVGYFKMTHKRVFKMAPIHHHFELKGWPEVKVVVRFWMIEMLFVLIALVLFYGDWVARSGL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUC2L_RAT
Sequence: VNCSVDCQLQVFNWSCPSTPSTPPPSTPTTPTSSQTTTPSTPSTTSSKSTPSTPQSTSSKSTPSTPPKTTLPGCLDFDPPRQVNETWWLCNCTMAICKYDNVVEIVELECNPPPMPTCSNGLKPVRVPDPDGCCWHWECDCYCTGWGDPHFVTFDGLYYSYQGNCTYVLVEEITPTVDNFGVYIDNYHCDANDKVSCPRTLIVHHETQEVLIKTVHMMPIEVEVQVNKQLVALPYKKYGLEVYQSGINFVVDIPRLGAQVSYNGLSFSIRLPYHLFGNNTKGQCGTCTNNTADDCILPSGEIISNCEVAADEWLVNDPSKPHCPHKGLTTKRPAITTPGPFPENCTVSPVCQLIMDSLFSQCHPFVPPKHYYEACLFDSCFVAGSGMECASVQAYAALCAQEGVCIDWRNHTQGACAVTCPAHRQYQACGPSEEPTCQSSSPKNSTLLVEGCFCPEGTTKFAPGYDVCVKICGCVGPDNVPREFGEHFEFDCKDCVCLEGGSGIVCQPKKCARGNLTTCEEDGTYLVVEADPDDKCCNTTSCKCDPKRCKAERPSCLLGFEVKSEHVPGKCCPVYSCVPKGVCVHENAEYQPGSPVYSNKCQDCVCTDSMDNSTQLNVISCTHVPCNISCSSGFELVEVPGECCKKCQQTHCIIKRPEQQYIILKPGEIQKNPNDRCTFFSCMKINNQLISSVSNITCPDFDPSDCVPGSITYMPNGCCKTCIHNPNNTVPCSAIPVMKEISYNGCAKNISMNFCAGSCGTFAMYSAQAQDLDHGCSCCREERTSVRMVSLDCPDGSKLSHSYTHIESCLCQGTVCELPQAQQSRTRRSSPRLLGRK
What are the official names of this protein?
Intestinal mucin-like protein, MLP.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_SPHAL
Sequence: MADKKIKIRQIGSPIRRPKDQRKILTGLGLGKMHREVELVDTPEVRGMIRKLPHMVEVID
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CCN1_RAT
Sequence: MSSSTIKTLAVAVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVSGQCCEEWVCDEDSIKDSLDDQDDLLGFDASEVELTRNNELIAIGKGSSLKRLPVFGTEPRVLYNPLHAHGQKCIVQTTSWSQCSKSCGTGISTRVTNDNSECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCSSVKKYRPKYCGSCVDGRCCTPLQTRTVKMRFRCEDGEMFSKNVMMIQSCKCNYNCPHPNEASFRLYSLFNDIHKFRD
What is the function of this protein?
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion.  Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity).  CCN1-mediated gene regulation is dependent on heparin-binding (By similarity).  Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity).  Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity).
What are the official names of this protein?
CCN family member 1, Cellular communication network factor 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein CYR61.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_KLEP3
Sequence: MAEKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDDKGQQPNPDFVLNFPQYKGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVTLSDEQVDELFKLVQANPGMTFEVDLEAQVVKAGDKTYSFKIDDFRRHCMLNGLDSIGLTLQHGEAISDYERKLPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: UGND_PSEAE
Sequence: MIDVNTVVEKFKSRQALIGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHIPQAKIAKARASGFEATTDFSRVSECDALILCVPTPLNKYREPDMSFVINTTDALKPYLRVGQVVSLESTTYPGTTEEELLPRVQEGGLVVGRDIYLVYSPEREDPGNPNFETRTIPKVIGGHTPQCLEVGIALYEQAIDRVVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVADRMGIDIFEVVDAAATKPFGFTPYYPGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSGEVNQAMPEYVLGKLMDGLNEAGRALKGSRVLVLGIAYKKNVDDMRESPSVEIMELIEAKGGMVAYSDPHVPVFPKMREHHFELSSEPLTAENLARFDAVVLATDHDKFDYELIKAEAKLVVDSRGKYRSPAAHIIKA
What is the function of this protein?
Plays a role in the biosynthesis of B-band O antigen for serotype O5.  Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA).
What are the official names of this protein?
UDP-N-acetyl-D-glucosamine 6-dehydrogenase, UDP-D-GlcNAc 6-dehydrogenase, UDP-N-acetylglucosamine 6-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SRC_DANRE
Sequence: MGGVKSKPKELGQRSRSLDDGTGGHHHHTPNPTSFTPNRSPPVEGSRRGTQPNIINAEQALFGGVNSTTNSITSPNRIGILGGVTTFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPGENL
What is the function of this protein?
Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors.  Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation.  Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each src kinase is very difficult.  Src appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families.  Receptor clustering or dimerization leads to recruitment of src to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains.  Plays an important role in the regulation of cytoskeletal organization through phosphorylation of specific substrates involved in this process (Probable).  When cells adhere via focal adhesions to the extracellular matrix, signals are transmitted by integrins into the cell resulting in tyrosine phosphorylation of a number of focal adhesion proteins, including ptk2/fak1 and paxillin (pxn) (By similarity).  Also active at the sites of cell-cell contact adherens junctions and at gap junctions.  Implicated in the regulation of pre-mRNA-processing (Probable).  Might be involved not only in mediating the transduction of mitogenic signals at the level of the plasma membrane but also in controlling progression through the cell cycle via interaction with regulatory proteins in the nucleus.  Involved in anchorage-independent cell growth (By similarity).
What are the official names of this protein?
Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Mitochondrion inner membrane. Nucleus. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, perinuclear region. Note=Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and the SH3 domain.
Protein: RUVA_LARHH
Sequence: MIGRLSGTLLEKHPPQILVDAGGVGYEVDVPMSTFCRLPGLNEPVVLWTHMAVREDAHLLFGFAGRAERELFRQLIRISGVGGKLALALLSSLEPDELARAVAQEDIKTLSRVPGIGKKTAERLILELRGKLGSLPSADLLSPAPAAGAALLVENDERADISQALQALGYSAREAEAALKSVPDGTDVATGIRLALKALARP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.