PharMolix/UniProtQA huggingface dataset:
Protein: SLMA_MARMS
Sequence: MSNKKNDRRTQILQALAQMLESSPGARITTAALAKQVGVSEAALYRHFPSKAKMFEGLIEFIEESLFTRINRIVQEESNVIARIEMIVTLVLGFAEQNPGMCRLLTADALAGETERLRVRITQVFDRIETQLKQVIREADLKQGLRPAMGVAPCANFLIAIIEGKIRHYVRSEFKVKPMEIWPEQWTVLAQNLMLNR
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HEMA_I77AB
Sequence: MKAKLLVLLCALSATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWILGNPECESLFSKKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKERSWPKHNVTRGVTASCSHKGKSSFYRNLLWLTEKNGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIEDQKTIYRKENAYVSVVSSNYNRRFTPEIAERPKVRGQAGRINYYWTLLEPGDTIIFEANGNLIAPWHAFALNRGFGSGIITSNASMDECDTKCQTPQGAINSSLPFQNIHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNKLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCNNECMESVKNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: GLYA_ACICJ
Sequence: MNQQSPIANISRFFNAPLAETDPDLAAAIGRELGRQQDGIELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRYYGGCAAVDIAEELAIARAKELFGCAFANVQPHSGAQANQAVFLALLNAGDTILGMSLAAGGHLTHGAAPNLSGKWFDAVQYGVKREDGTLDYEELERLARERKPKLIIAGGSAYPRFIDFARIRKVADEVGAYFMVDMAHFAGLVAAGIFPSPVPHAHVVTTTTHKTLRGPRGGMILSNDLDLGKKINSAVFPGLQGGPLMHVIAAKAVAFGEALRPEFRAYQKALAENAKVLAETLVEGGLDIVTGGTDCHLMLVDLRPKNVTGKAAEASLERAHMTANKNAIPFDPAKPAVTSGIRLGTPAATTRGFGPDEFRMVGRFIVEVLDGLSASNDGDNAAVEAAVGAKVLELCARFPIYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLH1_ORYSJ
Sequence: MAAANAPIAMREALTLTSLGIAPQFVTFTHVTMESEKYICVRETSPQNSVVIVDMAMPAQPLRRPITADSALMNPNTRILALKAQIPGTTQDHLQIFNIEAKTKIKSHQMPEQVVFWKWITPKLLGLVTQTSVYHWSIEGDSEPAKMFDRTANLANNQIINYRCDPSEKWLVLIGIAPGAPERPQLVKGNMQLFSVDQQRSQALEAHAASFASFKVVGNENPSTLICFASKTTNAGQITSKLHVIELGAQPGKPGFSKKQADLFFPPDFQDDFPVAMQISQKYGLIYVITKLGLLFVYDLETAAAVYRNRISPDPIFLTAESSASGGFYAINRRGQVLHATVNDATIVPFVSSQLNNLELAVNLAKRANLPGAENLVVQRFQELFAQTKYKEAAELAAESPQGLLRTPETVAKFQSVPVQAGQTPPLLQYFGTLLTRGKLNAYESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVDNDLALKIYIKARATPKVVAAFAERREFDKILIYSKQVGYTPDYLFLLQTILRTDPQGAVNFALMMSQMEGGCPVDYNTITDLFLQRNMIREATAFLLDVLKPNLPEHAFLQTKVLEINLVTYPNVADAILANGMFSHYDRPRVAQLCEKAGLYLRALQHYTELPDIKRVMVNTHAIEPQALVEFFGTLSREWALECMKDLLLVNLRGNLQIVVQAAKEYSEQLGVDACIKLFEQFKSYEGLYFFLGAYLSSSEDPDIHFKYIEAAARTGQIKEVERVTRESNFYDAEKTKNFLMEAKLPDARPLINVCDRFGFVPDLTHYLYTNNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFIKGLILSVRSLLPVEPLVDECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNNPEHFLTTNPFYDSRVVGKYCEKRDPTLAVVAYRRGQCDDELINVTNKNSLFKLQARYVVERMDGDLWDKVLQPENEYRRQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNLLILTAIKADPSRVMDYVNRLDNFDGPAVGEVAVEAQLFEEAFAIFKKFNLNVQAVNVLLDNIRSIERAEEFAFRVEEDAVWSQVAKAQLREGLVSEAIESFIRADDATHFLDVIRAAEEANVYDDLVKYLLMVRQKAREPKVDGELIFAYAKIDRLSDIEEFILMPNVANLQNVGDRLYDEELYEAAKIIYAFISNWAKLAVTLVKLKQFQGAVDAARKANSAKTWKEVCFACVDAEEFRLAQICGLNIIVQVDDLEEVSEYYQNRGCFNELISLMESGLGLERAHMGIFTELGVLYARYRPEKLMEHIKLFSTRLNIPKLIRACDEQQHWKELTYLYIQYDEFDNAATTIMNHSPDAWDHMQFKDVAVKVANVELYYKAVHFYLQEHPDLINDLLNVLALRLDHTRVVDIMRKAGQLHLVKPYMVAVQSNNVSAVNEALNELYVEEEDYERLRESVDMHDNFDQIGLAQKLEKHELLEMRRIAAYIYKKAGRWKQSIALSKKDNMYKDCMETCSQSGDRELSEDLLVYFIEQGKKECFASCLFICYDLIRADVALELAWMNNMVDFAFPYLLQFIREYTSKVDELVKDRIESQNEVRAKEKEEKDLVAQQNMYAQLLPLALPAPPGMGGPPPPMGMPGMPPMGGMGMPPMGPGPMPAYGMPPMGSY
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin heavy chain 1.
What is the protein family that this protein belongs to?
Belongs to the clathrin heavy chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: GCSH_XYLFT
Sequence: MSDIPGDLKFLKSHEWVRIEDNNRAIVGVSDHAQNLLGDLVYVELPNIGDHLDAGATAAVIESVKAASDIYSPVTGKVIEVNTTLSDKPETINEDPYGEGWIMVIEMQAPEEISNLLSPDDYTEVLESDEH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MNTH_STAS1
Sequence: MKNHVQTHNKSLDEINNTVSINTHGKFSQKLFSFLGPGLLVAVGYMDPGNWITSMQGGAQFGYILLFVILLSSLSAMLLQSMTIRLGISTGMDLAQATKHYLNKPVAFVFWIIAELAIIATDIAEVIGSAIALDLLFGIPLLVGALITVFDVFLLLFIMRFGFRKIEAIVGTLIFTVLVIFVFEVFIASPHVTEVLNGFVPSSTIITDNGALFIALGIIGATIMPHNLYLHSSIVQSRMYDRNSIQSKAHAIKYATMDSNIQLSIAFIVNCLLLVLGAALFFGVNTEQLGGFYDLYNALQNQPLLGASLGAIMSTLFAIALLASGQNSTITGTMAGQIVMEGFINLKIPNWLRRLITRLIAILPIIICLIVFNSNEAKMEQLLVFSQVFLSLALPFSLIPLQLSTNDKRLMGQFKNKLWVNIISWCLIIILSILNIYLIIQTFQEL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_PSESM
Sequence: MASLRIEVISLFPEMFSAISEYGITSRAVKQGLLQLTCWNPRDYTTDRHHTVDDRPFGGGPGMVMKIKPLEDALVQARQAAGDAAKVIYLSPQGRQLNQAAVRELAQEEAIILIAGRYEGIDERFIEAHVDEEWSIGDYVLSGGELPAMVLIDAVTRLLPGALGHVDSAEEDSFTDGLLDCPHYTRPEVYADQRVPDVLLSGNHAHIRRWRLQQSLGRTYERRADLLESRSLSGEEKKLLAEYIRERDDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RND3_MOUSE
Sequence: MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM
What is the function of this protein?
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
What are the official names of this protein?
Rho-related GTP-binding protein RhoE, Rho family GTPase 3, Rnd3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
Protein: SYDND_THENN
Sequence: MLRTHTCGELRVEDEGKKVKLCGWVDRIRDLGGVRFIDLRDRYGETQIVCDVNSKAYETVDELTRESVVLVEGTVRRRPEGTENPNIATGEIEVVAERIEILSKAEPLPFYPNETPKEEMRLRYRYIDLRSKRMRDNIILRYNITRVIRRYFDELGFLEIETPFLTKSTPEGARDFLVPSRLRPGKFYALPQSPQLFKQLLMISGFDRYFQIVRCFRDEDLRADRQPEFTQVDVEMSFVDVEDVLSVSEGMIARVFREAIGMDLKTPFDRITYSEAMEKYGTDKPDRRYGMELRDLGYAFEGTTFRVIRSVLEEGGSVKGFVVPEFASEMTRKKGDELMERAKELGLGGLIWFKVEEKIVSPHLKHLEREFKTIVEKENLKEGDVCLIAAHKDRNLLNEALGTLRLEIGKEYFSHLAKGFDILWVVDFPYFEWSEEEERFVARHHPFTMPVEETLGDDHTKVKAKAYDIVINGYEVGGGSIRIHKREIQEKIFKLLGMREEEAREKFGFFLEAFKYGVPPHGGIAFGLDRLVAIIAGENSIREVIPFPKTGNGVCLLTGAPSSVDEKQLRELRIRVEEG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SHEPA
Sequence: MSEKKINLLDLDRKALRALFTEMGEKPFRADQLMKWIYHFGVSDFEEMTNINKVLRAKLAAKCEIVAPEISSYQKSVDGTIKFAINVGDGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVAEIVGQIWRVADFIGFVKDTGERPITNVVMMGMGEPLLNLKNVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDKLGDVLDVALAVSIHAPNDELRDVLVPVNKKYPLEEFLGGIRRYIAKSNANRGRVTVEYVMLDHINDSTDQAHELAKLMKDTPCKVNLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKQMQQNQISVTIN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNCH_NOSP7
Sequence: MSFTYNRTVRFQDTDAAGVVYFANVLGICHEAYEESLEASSINLKDFFTNPSVAFPIVHASVDFLRPMFVGDKLLISLIPQKIGVEKFEITYEVTVAEVVVAKAITRHVCIDASSRSKQELPDEIVQWLETNRRDAEGAERRRSREIM
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: CA16_CONEB
Sequence: MGMRMMFTVFLLVVLATTVVSFTSDRAPDGRNAAAKAFGLITPTVRKGCCSNPACMLKNPNLC
What is the function of this protein?
This amidated peptide potently and teversibly inhibits Cav2. 2/CACNA1B.  Steady-state inactivation is enhanced at hyperpolarized membrane potentials.  Also shows a weak interaction at alpha-3-beta-4/ CHRNA3-CHRNB4 and alpha-7/CHRNA7 nAChRs subtypes.  In vivo, exhibits a potent analgesic activity in rat partial sciatic nerve injury and chronic constriction injury models.
What are the official names of this protein?
Omega-conotoxin Eu1.6, Alpha-conopeptide Eu1.6, Alpha-conotoxin Eb1.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APOA2_LEPWE
Sequence: MKLLALAVLLLAVCSLEGAFVRRQAEEPNLQSLVAQYFQTMTDYGKDLLEKAKGPELQAQAKAYFEKTQEQLTPLVKKAGTDLINFLSNFMDLRTQPATQ
What is the function of this protein?
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
What are the official names of this protein?
Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPC_NEIMB
Sequence: MTDILNKILATKAQEVAAQKAAVNAEHIRTLAAEAAPVRSFIDSIRGKHRLNLPAVIAEIKKASPSKGLIRPDFRPAEIARAYENAGAACLSVLTDEPYFQGSPEYLKQAREAVSLPVLRKDFIIDEYQVYQARAWGADAVLLIAAALEQEQLERFEAVAHELGMTVLLELHDETELEKCRNLTTPLWGVNNRNLRTFEVSLDQTLSLLPALEGKTVVTESGITGKADVEFMQSRGVHTFLIGETFMRADDIEAEVGKLF
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: VL1_HPV45
Sequence: MAHNIIYGHGIIIFLKNVNVFPIFLQMALWRPSDSTVYLPPPSVARVVSTDDYVSRTSIFYHAGSSRLLTVGNPYFRVVPNGAGNKQAVPKVSAYQYRVFRVALPDPNKFGLPDSTIYNPETQRLVWACVGMEIGRGQPLGIGLSGHPFYNKLDDTESAHAATAVITQDVRDNVSVDYKQTQLCILGCVPAIGEHWAKGTLCKPAQLQPGDCPPLELKNTIIEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGVMGDTVPTDLYIKGTSANMRETPGSCVYSPSPSGSIITSDSQLFNKPYWLHKAQGHNNGICWHNQLFVTVVDTTRSTNLTLCASTQNPVPSTYDPTKFKQYSRHVEEYDLQFIFQLCTITLTAEVMSYIHSMNSSILENWNFGVPPPPTTSLVDTYRFVQSVAVTCQKDTTPPEKQDPYDKLKFWTVDLKEKFSSDLDQYPLGRKFLVQAGLRRRPTIGPRKRPAASTSTASTASRPAKRVRIRSKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NADK_POLSJ
Sequence: MKSQFRHVALIGKYHAQGSRSALEDIAHFLGTQGCDVAIEQDTASNTGLTQFPTLDAAGIGAQCDLALVVGGDGTMLGIGRLLAQFGIPLVGINQGRLGFITDIAFEDYQDTLKPMLRGEFEEDRRWMMQAKVVRDGRCVFSATAMNDVVVNRGATAGMVELRVEVDGRFVANQRADGLIIASPTGSTAYALSAGGPLLHPSIPGWVLVPIAPHTLSNRPIVLSDAGEITVEIVAGRDASANFDMQSLATLLHGDRITVRRSEHQMRFLHPKGWSYFDTLRKKLHWNEGVA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_FRATO
Sequence: MQINISNLDVKNHLDKFIEDRLEYEFCKQDKYLYLENDNLKLHYNNKELFIDFNDSEILNRINPKTKKCSVVQAIEGRSKAKLTILDTTAGLGRDTFTLAARGHTLLTLEKDSYLYLLLKDALQRAQQINYLKEIANRITLINIDSNEYILTTDKSFDCVYVDPMFPPRKKSAKVKQGMQILHQVGFNDEVSNSNLLDNIIQTQISPKAVVKRPINAEFLSNKKPSSQLKGKTNRFDIYSL
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_FRATT
Sequence: MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAKSFGAKVVLTRDDHQSGTDRIAEAVTKLGFADEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLKVLYNGYKIAIEQSAKSTPAGVDTLQDLEKVRKLFNV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I82A8
Sequence: MDSNTITSFQDILQRMSKMQLESSSADLNGMITQFERLKIYRDSLGESVMRMGDLHSLQNRNATWRDELSQKFEEIRWLIAECRNILTRTENSFEQITFLQALQLLLEVESEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GGR_META3
Sequence: MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFGINPDPSFIRSKIDGGILVAPNGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIKSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESSIAEMAGIKCKKKVTEICSCAEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEHPLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGSIAGKVAGEAIKSNNCSEDYLVEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAMDERLEEIDVAKIAFRAVKRAPSLLKYFKDII
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: COAD_ALISL
Sequence: MTKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQDLPNVSVEGFSGLMVDFARQKQANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTPSEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKSPV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_CUPNH
Sequence: MSKLKELPLSALQFYATAPYACSYLDGRMARSQVATPAHLINADVYSRLVRAGFRRSGIFTYRPYCDECHACTPCRVVVDQFVPDRSQRRAWSRHQHLQALVAPLTYVEEHYSLYLLYQSMRHAGGGMDQDSRDQYEQFLLQSRVNSRLVEFREPPGSPEAGRLRMVSMIDVLDDGLSSVYTFYDPLERNASYGTYNILWQIRQTRELGLPHLYLGYWIADSRKMAYKARFRPLQVLTGNHWHAFEDEAGDAASPAPASNRD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_STRPB
Sequence: MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MTNA_DESVM
Sequence: MEHHIRYDAAQRALILLDQRLLPTRQEDFVCRTTEDIVTALQVMVVRGAPAIGVTAAWGCVLAAYEAAEAGDHWHPVLDGLLERIAKARPTAVNLRWAVDRMRKVWKTAGHAPFATLISLWESEARRIHRDDIEINRAMGRHGAALIDEGDTVMTHCNAGALATAGYGTALGVIRGAVDAGKKISVIANETRPFLQGARLTAYELHEDHIPVTVACDNACGHLMRKGMVQKVVVGADRIAANGDAANKIGTYSVALLAREHGVPFYVAAPLSTIDRNTPDGDHIPIEDRTPREVTHVGDTQITPDGVPVYNFAFDVTPAALIAGIVTEVGVLRPPYTESIAEAFRKAGLE
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PSBD_CYCTA
Sequence: MTVALGKSSKEEKNLFDIADDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVAFHGGFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.