PharMolix/UniProtQA huggingface dataset:
Protein: EF1A_AERPE
Sequence: MAEKPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAWILDKMKEERERGITIDLTFMKFETKKYVFTIIDAPGHRDFVKNMITGASQADAAILVVSARKGEFEAGMSTEGQTREHLLLARTMGIEQIIVAVNKMDAPDVNYDQKRYEFVVSVLKKFMKGLGYQVDKIPFIPVSAWKGDNLIERSPNMPWYNGPTLVEALDQLQPPAKPVDKPLRIPVQNVYSIPGAGTVPVGRVETGVLRVGDKVVFMPPGVVGEVRSIEMHYQQLQQAEPGDNIGFAVRGVSKSDIKRGDVAGHLDKPPTVAEEFEARIFVIWHPSAITVGYTPVIHVHTASVSSRIIEIKAKLDPKTGQVVEQNPQFLKAGDAAIVRFKPVKPLVVEKFSEIPQLGRFAMRDMNRTVGIGIVTDVKPAKVDIKAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_SYNR3
Sequence: MSMAEMRCPFSGHGAATTPASATTNQHWWPEQINLGLLHQHNPAANPLGSNFDYRQAFNSLDLNAVKADLMALMTDSQSWWPADWGHYGGLFIRMAWHSAGTYRLADGRGGAGHGNQRFAPLNSWPDNTNLDKARRLLWPIKAKYGSNLSWADLIILAGNCALESMGLPTAGFAGGREDIWEPEDDIYWGSETSWLSDERHDNDGAIESPLAATEMGLIYVNPEGPHGEPDPVASGREVRDTFARMGMNNEETVALVAGGHTFGKAHGAAPSAHLGADPEGAALEQLGLGWQNTYASGCGADTITSGIEGAWKPNPTRWDQGYFEMLFGYEWELHQSPAGAWQWHPKDVKAEHMIPDAHVPGRSAPPMMTTADLSLRFDPVYEPIARRFLGDPQAFGNAFAQAWFKLTHRDLGPRSCYLGADVPEAVMSWQDPLPTTSHPTIDAPAVDALKQELLNTGLSHGELISTAWASAASFRQSDRRGGANGARLRLQPQCNWELNNPEQLKRVLSVLEAVQMRFNQQHQGGMQVSLADLIVLSGSAAVEQAMAATGQRCRVRFTPGRVDASAEQTDNASFNALKPIADGFRNYLRSDLPLKAEQLLVDRAQQLHLSAPEMTALIGGFRVLGLNWDGSDIGVFTSRPGQFSNDFFVNLLDMSTQWSPVEGHSNLYQGIDTETKQPRWRASRVDLVFGSHAQLRAIAEVYGQAGGSARLAADFSAAWSKVMELDRFDLL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MISP_HUMAN
Sequence: MDRVTRYPILGIPQAHRGTGLVLDGDTSYTYHLVCMGPEASGWGQDEPQTWPTDHRAQQGVQRQGVSYSVHAYTGQPSPRGLHSENREDEGWQVYRLGARDAHQGRPTWALRPEDGEDKEMKTYRLDAGDADPRRLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDPRTPGPPRSTPLEENVVDREQIDFLAARQQFLSLEQANKGAPHSSPARGTPAGTTPGASQAPKAFNKPHLANGHVVPIKPQVKGVVREENKVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSSSQASGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKEQWYAGINPSDGINSEVLEAIRVTRHKNAMAERWESRIYASEEDD
What is the function of this protein?
Plays a role in mitotic spindle orientation and mitotic progression.  Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning.  May link microtubules to the actin cytospkeleton and focal adhesions.  May be required for directed cell migration and centrosome orientation.  May also be necessary for proper stacking of the Golgi apparatus.
What are the official names of this protein?
Mitotic interactor and substrate of PLK1, Mitotic spindle positioning protein.
What is the protein family that this protein belongs to?
Belongs to the MISP family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Predominantly localizes to cortical actin structures during interphase and mitosis. Present in retraction fibers, which are formed at former adhesion sites during mitosis, and at spicular membrane protrusions in re-attaching cytokinetic cells. Partially colocalizes with cytoplasmic F-actin. Not detected at microtubules at interphase, nor at spindle during mitosis.
Protein: PPK1_PACBA
Sequence: DGYTPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-1, PK-1, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_BACFR
Sequence: MKSFLVDQDGYYGEFGGAYVPEILHKCVEELQNTYLDVIESEDFKKEFDQLLRDYVGRPSPLYPARRLSEKYGCKMYLKREDLNHTGAHKINNTIGQILLARRMGKKRIIAETGAGQHGVATATVCALMNMECIVYMGKTDVERQHINVEKMKMLGATVVPVTSGNMTLKDATNEAIRDWCCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLQEKEGRDYPDYLIACVGGGSNAAGTIYHYIDDERVRIVLAEAGGKGIETGMTAATIQLGKMGIIHGARTFVIQNEDGQIEEPYSISAGLDYPGIGPMHANLADKKRAMVLAVNDDEAIRAAYELTRLEGIIPALESAHALGALEKITFKPEDVVVLTVSGRGDKDIETYLG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PYRG_HERAR
Sequence: MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFITAKMRKVNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQDYIYRGAEGFDVALVEIGGTVGDIESLPFLEAARQLSLRAGRNAAAFVHLTLVPYLVSAGELKTKPTQHSVQKLREIGISPDALLCRADRPIPDDERAKISLFSNVPEDAVISVWDADTIYKIPQMLYDQGLDRIVCEKLALSPKPADLSVWTKLVHALENPKHSVTIGMVGKYVDLTESYKSLTEALRHAGIHTESRVNIEYLDSEEIEASGPQCLAKYDAILVPGGFGKRGVEGKIAAARFAREHAIPYFGICLGMQVALIEYARNVAGLTKANSTEFDPDTEQPVVALINEWQNHDGKVERRDLNSDLGGTMRLGSQTCAVKPGTLAAEIYGNEVTERHRHRYEANNHYLGRVEEAGLIVSARTPAESLCEIMELPRTGEHAHPWYVGVQYHPEFNSTPRDGHPLFISFIKAALAHKQAEESKKVT
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: FETP_BURMA
Sequence: MARMIHCAKLGKEAEGLDFPPLPGELGKRLYESVSKQAWQDWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGEGADQASGYVPPAQG
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: DSC3_BOVIN
Sequence: MAAPGSGAPCAELCRQLLLTLVVFSFACEACKKEIFNIPSKLEADKMIGRVNLKECLGSVDRIQSSDPDFRVLEDGSVYTAHAVVLSDEKRSFTIWLSDTEKRTQKEILVLLEYQKKVLKKRHTKETVLRRSKRRWAPIPCSMQENSLGPFPLFLQQVQSDAAQNYTIFYSISGRGVDKEPLNLFFIERDTGNLYCTQPVDREEYDVFDLIAYASTADGYSADFPLPLPIRVEDENDNHPIFTEAVYNFEVPESSRVGTTVGVVCATDRDEPDTMHTRLKYSILEQTPRSPGLFSVHPSTGVITTVSHYLDREVADKYSLIMKVQDMDGQFFGLMSTATCIITVKDSNDNLPTFRQNAYEASVEENTVNVEILRIPVEDKDLINTANWRANFTILKGNENGHFKITTDKATNEGVLSVVKPLDYEESHQVVLEIGVANEAPFTRDVALRMTTMNRAVVTVHVKDQDEGPECSPEVQYIRIKENSAVGSKISGYKAYDPETKSSSGLRYKILHDPKEWITVNEGSGSLETYKTLDREVITPKNDLYNITVLAIDQDGRSCTGTLAVSIEDVNDNPPEILQDYLVICKGNMDYVDISAIDHDSSINGAPFYFSLANTSPEINRLWTITRVNDTAARLAYQKNAQFQEYFIPVAVKDRAGLSATKTLRVNLCDCTNPVQCRAARRSADVILGKWAILAILLGIALLFSILLTLVCGIVSARNKKAFPDDLAQQNLIISNTEAPGDDKVCSANGFMTQTVNNANQGFCGTMGSGVKNGGQESIEMVKGGQQTLESCRGAGHHHTLDSCRGGTIEVENSRYTYSEWQNFTQPRLGEKLHLCNQDEEHMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEAKFAALAKTCTKR
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.  May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
What are the official names of this protein?
Desmocollin-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: T23O_BACMK
Sequence: MKENEKVIMEKGIHTDFKENMTYGEYLQLDSLLSSQQRLSDHHDEMLFIVIHQASELWMKLILHELNAAIESIKQDKLPPAFKMLARVSKIQSQIIQSWDILATLTPSEYIEFRDSLGQASGFQSYQYRMIEYALGYKTPHALKIYEKDPELHARLHKALHTPSLYDVAIQALVKEGFPIHKDVLNRDITQPYEEDATVEAAWIEVYADVQKYWDLYQLAEKLIDIEDWLQQWRFRHMKTVERIIGHKMGTGGSSGVSYLKRVLDQCFFPELWNVRTKL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: ZN248_HUMAN
Sequence: MNKSQEQVSFKDVCVDFTQEEWYLLDPAQKILYRDVILENYSNLVSVGYCITKPEVIFKIEQGEEPWILEKGFPSQCHPERKWKVDDVLESSQENEDDHFWELLFHNNKTVSVENGDRGSKTFNLGTDPVSLRNYPYKICDSCEMNLKNISGLIISKKNCSRKKPDEFNVCEKLLLDIRHEKIPIGEKSYKYDQKRNAINYHQDLSQPSFGQSFEYSKNGQGFHDEAAFFTNKRSQIGETVCKYNECGRTFIESLKLNISQRPHLEMEPYGCSICGKSFCMNLRFGHQRALTKDNPYEYNEYGEIFCDNSAFIIHQGAYTRKILREYKVSDKTWEKSALLKHQIVHMGGKSYDYNENGSNFSKKSHLTQLRRAHTGEKTFECGECGKTFWEKSNLTQHQRTHTGEKPYECTECGKAFCQKPHLTNHQRTHTGEKPYECKQCGKTFCVKSNLTEHQRTHTGEKPYECNACGKSFCHRSALTVHQRTHTGEKPFICNECGKSFCVKSNLIVHQRTHTGEKPYKCNECGKTFCEKSALTKHQRTHTGEKPYECNACGKTFSQRSVLTKHQRIHTRVKALSTS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 248.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOC_MYCTA
Sequence: MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LITO_RANAE
Sequence: QQWAVGHFM
What are the official names of this protein?
Litorin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUE_ECOUT
Sequence: MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGKNSETKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTLELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
What is the function of this protein?
Exporter of leucine.
What are the official names of this protein?
Leucine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DTD_CITK8
Sequence: MIALIQRVTRASVTVEGEVTGEIGQGLLVLLGVERDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPGFSRGAAPDRAEALYEYFVERCCQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX2_PICPA
Sequence: MPNRLIPLANPANRVLQLDAKLLDNEISDMLYRQLSGAFNSNRLPSWLGRIHSNYASELKLLLELLIFKVTVWNKHSSYGLTLQNLVMYDGGVHNKKFRSKQQSELRVTKKILLLSSVLLGYFVKKIQSYVYSFEDYDLETDGEDLSTLERIRLKTIKLLKSQISTLEKAHSVLSLVNFVTFLVSGSFPDLTTRILNIRFKPLVTTQVAFASNPETISYEFQNRQLVWNTLTEFIVFILPALSVPKFTKSLVSSITGTSPKSSQVTDEDLKVFSSLPERVCAICFQNSQNSDSGAQNDISLNDTLVTNPYETTCGHIYCYVCILSKLQIFKEEGKNLPKSDPNKYWHCLRCNEPASWCRVYTGDVEDALRQKAVEEVTEDEDASSEDEEKRDQDSEGAKTVSQSFHHVNGSDYQTASFIEQAELNENEYTDGSEVEIYDAEDEYTDEEVDDDSPGFFVGAL
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 or PEX20 receptors from peroxisomes to the cytosol, thereby promoting PEX5 and PEX20 recycling (PubMed:23344950).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 and PEX20 through the peroxisomal membrane (By similarity).  PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase (By similarity).  PEX2 ubiquitinates PEX5 or PEX20 during their passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 and/or PEX20 at 'Cys-6' and 'Cys-8', respectively, a modification that acts as a signal for PEX5 or PEX20 extraction into the cytosol (By similarity).
What are the official names of this protein?
Peroxisomal biogenesis factor 2, Peroxin-2, Peroxisomal protein PER6.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: GUAA_RUTMC
Sequence: MMNNIHLDKILILDFGSQYTQLIARRVREIGVYCELFPYDVDSEFIKKLNPKGIILSGGPDTVTLDNAAKAPSIIFDLNIPILGICYGMQTMAIQLGGRATSANKHEYGFAKVRVRNHSPLLSDISDEGHGLLDVWMSHGIEVEQLPNGFKLIASTDNCNIAGFANVEKHYYGLQFHPEVTHTKQGERILERFISGICQCEKNWTTDNIIAKLVQNLKDQIGNANILLGLSGGVDSLVVAVLLQQAVGKQLTCVFVDNGLLRFNEGNEVMQIFAQNMDMKVIRANAHKKFYDALLNENEPEAKRKIIGRAFIEVFEEEAKKLDNIQFLAQGTIYPDVIESADAKYGKAKLIKSHHNVGGLPNDLQFKLVEPLKELFKDEVRKISVKLSIPPHIIYRHPFPGPGLGVRILGQVKQEYANILRQADAIFMDELHKNNLYDTVNQAFAVFLPIKSVGITGDERRYDYVIALRAVETIDFMTARWARLPYDFLDLVSNRIMNEISRISRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PDXT_ARTS2
Sequence: MTNPPSTDYSRAGAGLRIGVLALQGDFREHLRAAEATGATGIGIRRPSELDGIDGLIIPGGESTAIDKLARAFELADPLRKLIAEGLPVYGSCAGMILLADEIADPATDLAGNPQQTFGGLDITVRRNAFGRQRESFEIDLEFKGLGFSDTGSGVAPVHAVFIRGPWVERVGPGVEVLAQVEPADPAHASHAAALQGTARIVAVRSGHLLATSFHPEVTGEKRVHELFIRMIRGEA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: MPTN_METMP
Sequence: MRMGIISEERDWVTDELKSKMEKNDIDPVIIQPSKIISYIESEVKFEQNNRSILDLKCAFVRNIGEGVEMFHRFDMLKYLENYVPIINPMDGIENAGNKFRTSFLMEVHKIPHPKTIVAEDVNKALIAADKFEDVVLKPLFGNQGKGLVRVKGRSTVAKLKALNTFKSTHGVIYMQEFVNNPNNVYRDIRAFVVGDKVISAMYRTSDNWITNIHQNGVPEKCEITEELSKIVLAAKDAVGLVYAGVDILESSDGLKVIEVNACPSWEGLSRISEVDIAQNLIDEALNYAKEY
What is the function of this protein?
Catalyzes the ATP or GTP-dependent addition of one L-glutamate molecule to tetrahydromethanopterin, producing tetrahydrosarcinapterin.
What are the official names of this protein?
Tetrahydromethanopterin:alpha-L-glutamate ligase, H(4)MPT:alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family. MptN subfamily.
Protein: 1B01_SAGOE
Sequence: MTVMAPRTLLLLLSGALVLTETWAGSHSMRYFSTAVSRPGREEPRYIEVGYVDDTQFVRFDSDAASPRMEPRAQWVEKEGREYWEEETQRAKAFAQTFRVNLQTALGYYNQSEAGSHTIQMMSGCDLGPDGRLLRGYDQHAYDGKDYISLNEDLRSWTAADVAAQITQRKWEAANEAERTRAYLEGTCVEWLHRYLENGKETLQRAEPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDMELVETRPTGNGTFQKWAAVVVLSGEEHRYTCHVQHEGLPEPLTLRWEPPSQPTIPIMGIVAILAILGAVVTGAVVTAVMWRKKSSDKKGGSYSQAARSDSAQGSDVSLTACKV
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Class I histocompatibility antigen, B alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MNMG_HELPG
Sequence: MVKESDILVVGGGHAGIEASLVAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKEVDVLGGAMGIITDNSGLQYRVLNASKGPAVRGTRAQIDMDTYRIFARNLVLSTPNLSVSQEMTESLIIKNDEVVGVTTNINNTYKAKKVIITTGTFLKGVVHIGEHQNQNGRFGENASNSLALNLRELGFKVDRLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCFITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIHKSEYYINGLSTSLPLDVQEKVIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQAPFILKRNEAYIGVLIDDLITKGTNEPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEQDFYKELEKDKQAIQENLKRLKECVLTPSKEVLKRLNELDENPINDKMDGVSLLARDSFNIEKMRSFFSFLAPLNERVLEQIKIECKYNIYIEKQHENIAKMDSMLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEISGITPANLDVLHLYIHLRKNS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_ECO27
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVSGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_LISMF
Sequence: MVKQIMIQGTASDAGKSVLVAGLCRLFKNKGKRVVPFKSQNMSLNSFITATGDEMGRAQVFQAEAAGVFPDVRMNPVLLKPTNDRQSQVIFMGAILDNMDAVTYHDFKQTLIPKIQAVYQSLADENDIIVLEGAGSPAEINLNDRDIVNMGMAKMVDAPVVLVADIDKGGVFASIYGTIMLLNEEERARIKGVIINKFRGDVALLQPGIDMIEELTNVPVIGVIPYANLQLEEEDSVSLSGKNYVPDSNALLDIAIICLPRISNFTDFHSLEIQPEISLRYIRNLADFGKPDLVIIPGSKNTLEDMAFLEESGLKKAIQNFAENAGKVIGICGGYQMLGKKMLDPNQVESKQLEIAGLGLLDTETIFLDQKRTTQITGVTHSGEAVEGYEIHMGETKRGESTSPFCEIKAVNGNEETHQDGAISVNKNIIGTYIHGIFDNDVFLGNLFDELLTRKNKSVYPHEIINLKEHKEQEYDKLAALLEANIQMDQLEKIMKGEKICVSTQKPAIKE
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: HLDD_CUPMC
Sequence: MTIIVTGAAGFIGSNIVKGLNERGETNIIAVDNLTRAEKFNNLVDCEIADYLDKTDFVARFARGDFGNVRAVFHEGACSDTMETDGRYMMENNYRYTLALLEACLEQGAQFLYASSAATYGASTMFREDRDYEKPLNVYGYSKFLFDQVVRRRLPSAHSQIVGFRYFNVYGPREFHKGRMASVAFHHFNQFRAEGTVKLFGEYNGYAPGTQSRDFVSVEDVVKVNLYFLDHPEKSGIFNLGTGRSQPFNDIAVSVVNALRESEGKPALSLDEMVQEGLVEYVKFPDALRGKYQCFTQSDVSRLRGAGYSDQFLTVQEGVSRYCKWLLERSA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: NOG2_MOUSE
Sequence: MVKPKYKGRSTINRSAASTNPDRVQGAGGQNMRDRGTIRRLNMYRQKERRNSRGKVIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQASLQKFQEEMDKVMKDPYKVVMKQSKLPMSLLHDRIQPHNAKVHILDTESFESTFGPKSQRKRPNLFASDMQSLLENAEMSTESYDQGKDRDLVMEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKAPQDHIGAVLERAKPEYISKTYKIESWENAEDFLEKLALRTGKLLKGGEPDMLTVSKMVLNDWQRGRIPFFVKPPNAELPTDSQLPPSSPLEVPTETTQNNPEEETTETEVERSDSITEKEPEGDCSQDRNSEMQQILARVRQNFGKINVGPQFSADDLVPVEMSDLEDLESSGEEEEQEQEQPGEDAEEERSPDTQEEPVGNDTKAVLRALDEKIAKYQRFLNKAKAKKFSAVRISKDLSEKVFAKYKEEKKTSAEDSDAAPTKKARKWDAQMEEEPSNKTQRMLTCKERRRAARQQQSKKVGVRYYETHNVKNRNRNKKKTSDSEGQKHRRNKFRQKQ
What is the function of this protein?
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.  May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
What are the official names of this protein?
Nucleolar GTP-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KCNN3_PIG
Sequence: MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQPPPPPPPPAPPAAPQQPPGPPLQPQPLQLQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSALMEARGVSVAVGTTHTPLSDSPIGVSSTSFPTPYTSSSSC
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:11877319).  Activation is followed by membrane hyperpolarization (PubMed:11877319).  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (PubMed:11877319).
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.