PharMolix/UniProtQA huggingface dataset:
Protein: FMT_CLAMS
Sequence: MRLVFAGTPLAAVPSLQRLAASGHEVALVVTRADAPLGRKRVLTPSPVAAEAERLGIPTLRVNRLDDDATARIAAVGAELGVIVAYGGLVREPLLSTPARGWINLHFSLLPRWRGAAPVQRSIMAGERVTGASVFQLERGMDTGPVFSMEERPTGDHETAGHVLDALAVQGADLLARTVDAIGAGTAVARPQEGEPTLAPKTTIDDGRVDWARSADEVLARIRGVTPEPGAHTSVDDVRLKIHRAAALRDAAPLEPGRIAALDGRVAIGTASHPVELIQVQPAGKSPMPAADWWRGVTTKDVIAR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PSTB_RALSO
Sequence: MTMTATSIDVRVQSPKIDVRDLNFYYGKFHALKNISLQIPEKQVTAFIGPSGCGKSTLLRTFNKMYALYPEQRAEGEINMDGENLLTSRMDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVKLFERLSRSEMDDRVEWALTKAALWGEVKDKLHQSGYGLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGKIEELIAELKDDYTVVIVTHNMQQAARCSDYTAYMYLGELIEFGETEKIFIKPRRKETEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MATRX_PHODV
Sequence: MTEVYDFDRSSWDTKGSLAPILPTTYPDGRLIPQVRVIDPGLGDRKDECFMYIFLLGIIEDNDDLGPPIGRSFGSLPLGVGRTAARPEELLKEATLLDIVVRRTASVKEQLVFYNNTPLHVLTPWRKVLTNGSVFSANQVCNAVNLIPLDTAQRFRVVYMSITRLSDDGCYRIPRGMFDFRCKNALAFNILVTIQVEGDFCSNRGNLSMFKDQQATFMVHIGNFSRKKNQAYSADYCKLKIEKMGLVFALGGIGGTSLHIRCTGKMSKTLNAQLGFKKILCYPLMEINEDLNRMLWRLECKIVRIQAVLQPSVPQEFRIYNDVIISDDQGLFKIL
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: S20A2_XENLA
Sequence: MVLDEYMWMVIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVNLYNNTVDLLMAGEVSAMVGSAVWQLIASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIKFFILNKEDPVPNGLKALPVFYAATIGINVFSILFTGAPLLGLQTFPVWATALLSVGIAIVFALVVWFFVCPWMKKKIASRLKKEGALSRISEESLDKIQDEDTSVFKELPGAKGNDESVLPLTSSSPDAAVSSESVSNGNTRVPYGRAASMTNGSIRSPFSNGTFNFDGHTVKSDAHVYHTVHKDSGLYKDLLHNIHLDRVKIDRSAPENNYRILRRNNSYTCYTAAICGVPVHSTFKSSDIAMPEDSEKLVGDTVSFSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLAAELADPNPPQDDSLEEDKEEKDKSQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLVALWLIYQQGGVMQEASTPVWLLLYGGVGICAGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVVASNIGLPISTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGLFSAGVMAILQYGILPYV
What is the function of this protein?
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis.
What are the official names of this protein?
Sodium-dependent phosphate transporter 2, Solute carrier family 20 member 2.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUTD_ECO1A
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: SKP1_NEUCR
Sequence: MAENDERALQKVSLQSNDGQIITVDRVVAERSLLIKNLIEDLGDEAVMNEAIPLPNVNEPVLRKVVEWCEHHRKDPPQTTEDENDSRKKSTEIDEWDQKFMQVDQEMLFEIILAANYMDIKPLLDVGCKTVANMIKGKSPEEIRKTFNITNDFTPEEEEQIRRENEWAEDR
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).
What are the official names of this protein?
E3 ubiquitin ligase complex SCF subunit scon-3, Sulfur control protein 3, Sulfur metabolite repression control scon-3.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: COX10_GIBZE
Sequence: MRPPRCLFPAAEILLKAPPSRRCMSSAAAFQPPKIVAAIPWKGSSFFLSNRLFDRSTCLDFVVLRRANGIRSTSASASTTHDSTLSSSPTANHSTSAHKDHKIAPHRKRQAQRREKAAAEAAAAAARGEKPLPPDASSLLAAHAASQTSPLRRHLSACLSLAKPRLTMLVVLTAMATYALYPVPEMLSPSTTETPSLSPLTLLFLTIGTTFCSASANALNMLYEPSTDAKMTRTRNRPLVRNLISKRAAVLFAILSGFVGTGALYFGVNPTVSGLGFANIVIYAGMYTPLKAVTAFNTWIGAVVGGIPPLMGWAAAAGETATKDGSWRELLFASDGSSIGGWVMAGLLFAWQFPHFMALSWPIREEYKKAGLRMLAWTNPARNGRVALRYSFVFIPLCLSLCAAGVTEWSFAVTSFPINAWLIRESVRFWRYEGNKGSARGLFWASVWHLPGVMILALLHKKGMWTRVWRSVFGEDEGEWEEEELDEMMSVAVANTNSHMQNQKTVR
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RGYR_PYRAB
Sequence: MKAIYRGMCPNCGGAITDERLAEKNPCEGCLSEPIKAEDYEKLVFAVRNALKLRGTLKDWEDLYRLNKEVSEVEDLFKRATGFRFWSAQRTWVKRILRGKSFSIIAPTGMGKSTFGAFISIYFAIKGKRSYIVVPTTPLVVQTVKKIQDMMERAGVNVRLVYYHGNLKKKEKEEALKRIKDGDFDILVTSSQFLATRFDELLRDKRFDLIFVDDVDAFLKASKNIDRSLLLLGFTQEVINRAWEVIKLKKQLAKLLQAQGKEKEVEELNKEIEKIEREIERYRRENNIGILIVASATGSARGDRIKLYRELLGFEVGSGRSVLRNIVDTYIIPERSIEEEVENLLRKLGKGGLIFVPIDKGIEFAEELTNYLKSKGFKVELVSAKNKRGLELFERGEVDYLVGVATYYGTIVRGLDLPHLIRFAVFAGVPKFRFSMDLEQPTIYRVLGLMSEILEFLPQEKREEGEKLYARLRRLIRNIPQYELMKIEEALAEGIELEGFHNHVLDVFKQAVEFLREVLRDEEVIRRISENPFLSLKEVEGKLYIEIPDVRTYIQASGRTSRLFAGGITKGLSVIIVDDQKVFNGLIRQMRWRFVEFEIKKFEEINLESVLREIDEDRKKVRLVIEGKISEQVKDLVKSALMIVESPNKARTIASFFGQPSKRRIGELVAYEVSIGDKMLTILASGGHMFDLVTTEGYHGVLILKDDGKPYYVPVYDTIKRCRDCGHQFVDWEQKGVCPKCGSRNVHDALENVKAMRELALEVDEILIGTDPDTEGEKIAWDIRNVLSPYTPNIKRIEFHEVTRPAILKAIKEARDINEDRVKAQLVRRIEDRWIGFELSQKLWEVFENRNLSAGRVQTPVLGWIVQRYKEFTESETDFLGLTLENGISITIENAKGEVKEVEVKDVVIEEREINPLPPYTTDAMLQDASRFLGFSATKTMQLAQDLFELGLCTYHRTDSIHVSNTGIEIAKEYISEEIGEEYFAPRKWGEEGAHEAIRPTRPIDTGRLIQLIRDGIITLPRNLTKDHFRLYDLIFRRFIASQMKPARVLYEKAIISTPFGDVEVEGYIEILYDGWSRVKPLPLKQIPKLEKGQKLKVTEIKQWRAPKVSLYTQGDVIALMKERGIGRPSTYAKIVQTLLQRGYVIETKGRKKLVPTEKGIKVYQYLVSKYKDLVSEERTRQLEKIMDEIEEAKADYQEVLRELHEEIKRYIRS
What is the function of this protein?
Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process.  It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue.  May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
What are the official names of this protein?
Reverse gyrase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
Protein: CAPSD_AMVYS
Sequence: MSSSQKKAGGKAGKPTKRSQNYAALRKARLPKPPALKVPVAKPTNTILPQTGCVWQSLGTPLSLSSFNGLGVRFLYSFLKDFAGPRILEEDLIYRMVFSITPSHAGTFCLTDDVTTEDGRAVAHGNPMQEFPHGAFHANEKFGFELVFTAPTHAGMQNQNFKHSYAVALCLDFDAQPEGSKNPSYRFNEVWVERKAFPRAGPLRSLITVGLLDEADDLDRH
What is the function of this protein?
Capsid protein.  Binds to the to the 3' end of the nonpolyadenylated viral RNA and is involved in viral RNA translation initiation.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the alphamovirus/ilarvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: METK_LIMF3
Sequence: MKERHLFTSESVSEGHPDKIADQISDAILDALLEKDPDARVAVETSVTTGLALVFGEISTSAYVDIQHVVRETIKEIGYTDGKYGFDGDNCAVIVALDEQSKDIAQGVDDSLEIREGQVDPLDQIGAGDQGLMFGFATDETPEYMPLPLILSHKLMRRIAILRKDKVIKYLRPDAKAEVTVEYDADGKPVRVDTVVLSTQHDPDVSLEQIQADVKEQVIKAVIPAEYLDDQTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGAAHHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGYAKKLEIQVAYAIGVAKPVSISIDNFGTGTKSEEEMIAAVRQVFDLRPAGIIKMLDLQRPIYKQTAAYGHFGRTDIDLPWEKLDKVAELKKILG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BRUC2
Sequence: MFNTHKVEIEWGGRPLTLETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAKEHFFPEGVEETEMSAEQFATIFKHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SG2A1_RAT
Sequence: MKLVFLFLLVTIPICCYASGSGCSILDEVIRGTINSTVTLHDYMKLVKPYVHDHFTANAVKQFKQCFLDQTNKTVENVGVMTEAIFNSESCQQPS
What is the function of this protein?
Part of prostatein which is the major secretory glycoprotein of ventral prostate gland.  Steroid-binding protein; can bind non-polar steroids, cholesterol and a group of small proline-rich peptides (By similarity).
What are the official names of this protein?
Secretoglobin family 2A member 1, Prostatic steroid-binding protein C3.2.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3E_CHAGB
Sequence: MASAPNANGDAAVSDYDLMLKLAQNLDRHMIFPLLEFSAGQLVDEESGVVRDEAKAREITQAKYSLLKNSNMTDYVANLYCELAGVEEPPAEFADKKQKVFSQLQNLEQQTSKIIELLEREDVVNNLRSDKVANLEFLKREHQVTMDMVNALFDLGNLQYSCGNYGDASEMLYRFRVLSTDNDKVAFATWGRLACEILTMNWESAMEELVKVRETIDTKLSQNPLAQLQHRTALTHWALFPLFNFEKAREPILELFFNAGYINTIQANCPWILRYLAVAVITNRGRAKNPGIHQKQMKDVVRIVKQEAYEYQDPITRFVHALAIDFDFEEAQRQLVLAEEVLRSDFFLLAHADDFVDSARHLIFESYCKIHARISLKDLSARLGLNADAAEKWIVNLIRDTRLDAKIDYKEGTVVMNHPPSSVYQQVIEKTKGGFFRTQVLTAAIAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_PARPJ
Sequence: MSTWLLPENIADVLPSEARKIEELRRHLLDRFRSYGYEMVMPPLLEYIESLLTGGGHDLNLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGNVAHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALRLAGLAKVRLDLCHAGVLAALIEAEPAAAELGQSLYDALAGKDVPRLVELTANLTPVIRDALRALPTLYGDASVLDEARARLPNAPAIARALDDLAFLASQVEGAEVMIDLADLRGYAYHSGVMFSAYVDGVPNAVARGGRYDHVGQAYGRARAATGFSLDLREVARISPVEARSSAILAPWQHDEALRVSVAALRDAGEVVIQALPGHEHDLDEFAFDRVLVERNGNWVVEARA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1336_YERE8
Sequence: MDMTNAQRLILSNQYKMMTMLDPENAERYRRQQTIVERGFGLQMRELDRDFGEMSEDTCRTIINIMEMHHALQVSWDNLKDKQDLDERRIAFLGFDAATESRYLSYVRFMVNTEGRYTHFDSGTHGFNSQTPMWDKYQRMLAIWQSCPRQYHLSAVEISQIINA
What are the official names of this protein?
UPF0304 protein YE1336.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: VAP14_ARATH
Sequence: MSTDELLTFDHVDIRFPIELNKQGSCSLNLTNKTDNYVAFKAQTTKPKMYCVKPSVGVVLPRSSCEVLVVMQALKEAPADRQCKDKLLFQCKVVEPGTMDKEVTSEMFSKEAGHRVEETIFKIIYVAPPQPQSPVQEGLEDGSSPSASVSDKGNASEVFVGPSVGIVDLIRMSDELLIIDPVDVQFPIELNKKVSCSLNLTNKTENYVAFKAKTTNAKKYYVRPNVGVVLPRSSCEVLVIMQALKEAPADMQCRDKLLFQCKVVEPETTAKDVTSEMFSKEAGHPAEETRLKVMYVTPPQPPSPVQEGTEEGSSPRASVSDNGNASEAFVDMLRSLLVPLFSNAASSTDDHGITLPQYQVFINFRGDELRNSFVGFLVKAMRLEKINVFTDEVELRGTNLNYLFRRIEESRVAVAIFSERYTESCWCLDELVKMKEQMEQGKLVVVPVFYRLNATACKRFMGAFGDNLRNLEWEYRSEPERIQKWKEALSSVFSNIGLTSDIRRYNLINKNMDHTSEFLYIVLILNFFSEISDMTGLTTSYQFLLMMKSNLISYDIYIYPTKFCVNVFIGV
What is the function of this protein?
May play a role in vesicle trafficking.
What are the official names of this protein?
Vesicle-associated protein 1-4, Plant VAP homolog 14, AtPVA14, VAMP-associated protein 1-4.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
Protein: EXG2_SCHPO
Sequence: MSNLLEAESSCDSKSLGVDDFTSKRCREIDKKALLITILLTFFVSLCVFLSIILPLIFLVIIPHAQSDRKIKDTNMETTNLGVNIIDEIFNSTQVPEWAKNSLLDTNTWLDTSDFNTSFTNETFAGLYTMGIFDKYDDSVQANPNVPPLNEPFPYGRLPIRGVNLGGWLSMEPFITPSFFQVKNETAYLVKDELSLHAYLGENATSVIENHYNTFVTKQTFYEIREAGLDHVRITFPYWILYSNEITNVSGIGWRYLLRSIEWAREQGLRVNLDLHAAPGNQNSWNHGGYLNQMEWLDGTVKGEENSQFTLKIHERLASFFSQKRYRNVVTIYGALNEPNFFVLDEHKITDWHKQAYAVIRQSNFTGLISLSDGFRGPGNWEDHFDPFHFPNILIDVHRYIIFNDFLIGLRPKDKLNVICKSWNEEMKLKAKLPTIIGEWSLADTDCAKFLNNVGEGARWDGTFTPNGGVASCSEKVGCRCDFANQDPENYEDSYRKFLYALATSQIETFDKTWGWFYWNWDTENATQWSYKKSWLAGLLPRLAYSTTKDFNCSMLDSKSFMEFDEQSEF
What are the official names of this protein?
Glucan 1,3-beta-glucosidase 2, Exo-1,3-beta-glucanase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DHSDA_DANRE
Sequence: MASLIRLSSVWQRGMRPVLLCHTQLSRGSACPRIGDVDYTEPAGRIHTASSSTGISASQHWTGERVMTLVLLGMAPAAYLCPGPVVDYSIAAALTMHGHWGIGQVLTDYVHGEVKIKLAKVGIFLLSTATFFGLCYFNYNDVGLCKAVVMLWQK
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial, CybS-A, Succinate dehydrogenase complex subunit D-A, Succinate-ubiquinone oxidoreductase cytochrome b small subunit A, Succinate-ubiquinone reductase membrane anchor subunit A.
What is the protein family that this protein belongs to?
Belongs to the CybS family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SCIN_HUMAN
Sequence: MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW
What is the function of this protein?
Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane (PubMed:8547642, PubMed:26365202).  Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity).  In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+).  Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (PubMed:11568009).  Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (By similarity).  Regulates chondrocyte proliferation and differentiation (By similarity).  Inhibits cell proliferation and tumorigenesis.  Signaling is mediated by MAPK, p38 and JNK pathways (PubMed:11568009).
What are the official names of this protein?
Scinderin, Adseverin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, podosome.
Protein: AROD_LACPL
Sequence: MQPAIKLRNIELGSCRPKLAVPITGTTINDILAATTPILAAQPDVVEWRIDFFKDVTNPEQLKSAGQQLRQALGDIALLTTFRTKGEGGELALSDTEYFKLCETVLDGGFTDALDVERYHDEQAVKQIVAAAHEHQVVVIMSNHDFDKTPAVAEIVKRLTSMVDYGADVAKMAVMPQSVEDVLTLLTATNIARQTLPQPVITMSMGDLGKVSRLAGEVFGSCLSFATVGAASAPGQIALENLRPELEDLKLN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ACT2_SOLLC
Sequence: AGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYDGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDNLMKILTERGYMFTTTAEREIVRDMKEKLAYVALDYEQEIETARSSSSIEKNYELPDGQVITIGAERFGCPEVLFQPSMIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQ
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-51.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SRS2_SCHPO
Sequence: METKSSYLKFLNEEQRISVQSPHKYTQILAGPGSGKTRVLTARVAYLLQKNHIAAEDLIIATFTNKAANEIKLRIEAILGNSEASKLISGTFHSIAYKYLVKYGKHIGLSSNWLIADRNDTQAIMKRLLDSLKKAKNPIASGIRGQELTPQNALNRITKLKSNGLLVKPGMDQLSLINGLEEPPKELQSHQSVELYRLYQTSLWKNNLADFDDLLLNFILLLQKQPDCVRNIKHILIDEFQDTSKIQYFLVKLLALQNSDITIVGDPDQSIYGFRSAEIRNLNQMSEDFEGTQVLHLERNYRSAKPILELALSIISQDKSRPKKGLKSNHISSLKPHYRLFETNNKESYWIAREIKRIVGSCPELIFYNDIAILVRSSSLTRSLEHALSELGVPYRMVGVNKFFDREEIRDLIAYLRVLANKDSTSLIRVINVPPRNIGKTKIDRIIFESERRGLTFWQTLNEVKNENILLSQRNDKSFLKSLKSFLCSISKLENRYLSNGHSATLSDLLLGILSEIKYYEYLVRKNKETVEEKWENVMELVQQSDNISCIFYELDYKISTIVLLQNFLTQIALVNEEQKEGESQKVTISTLHAAKGLEWPVVFLPCLCENIIPHSRSDDLDEERRLLYVGATRAQALLYLSSFKSVTGMFADMQNSDNVQDVSPFLKGEEMKRWVMESEIVFNEKIASEIGTILGRKSYGKITNLSGIGSNANHNGTKFENLGFQCCRVLAEAELKKRERVKSVNDYNKDETNFRKHNAKRSKTDIRSWFEKKQPIDSDVEISEPSRSASIMVANKDLNDRSFETVNRIVSTRASTTNASFMSSVRQNLGRGPSTKDQVINRTLREGHQDVVQHTDLNQSNTKVASARPAGSRKRLGVRLRVSRML
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions.  Also aids the recombinational repair of camptothecin-induced collapsed replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase srs2, DNA 3'-5' helicase srs2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR19_NANDO
Sequence: MTRSLKKNPFVANHLLGKIEKLNMRAEKEIIVTWSRASTIIPIMIGHTIAIHNGKEHLPIYITESMVGHKLGEFAPTLTFRGHARNDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KDPA_ECO55
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.