PharMolix/UniProtQA huggingface dataset:
Protein: SYLC_CAEEL
Sequence: MSKINKERKKVAQLQEIEKSIQELWESKKAFEADARDDGKPKYLVTFPFPYMNGRLHLGHTFSASKCEFAAGFQRLQGKEVLFPFGFHCTGMPIKACADKLKREMQDFGYPPNFPEDVVEEVKEEVSAVDEIIKDKSKGKKSKLVAKTGNAKYQWQIMKSLGLCDEEIKEFSDPNHWLYYFPPHCIADLKKMGLKADWRRSFITTDVNPYFDSFVRWQFNLLRAAKKIDFGKRYTIYSPKDGQPCMDHDRASGEGVGPQEYTLIKLKVLDPKPQALSHIKEDIYLVAATLRPETMYGQTNCYLHPDIQYSVFYATENEKQVFVATARSARIMSYQGLTKENGKVNYVLGLEKIAGSKILGAPLSAPLAKYERVYALPMLTIKDDKGTGVVTSVPSDSPDDFAALSDLKKKKPLREKYGLTDEMVLPFEPVPIIKIEGLGDLAAVEMCSRLKIESQNEKDKLEEAKKEVYLKGFYDGVMLVGKYAGKKTADVKKVIQDDLTAEGLATKYVEPEKKVMSRSGDECVVALCDQWYLNYGEAEWKAAAKKVLEPLRTFNDETRRGLETTVDWLHEYACSRSYGLGTKLPWDTQYLIESLSDSTIYNAYYTVAHLLQQGAFDGSVVGPAGIKADQMTDASWSYVFLGEIYDSKTMPVEEEKLKSLRKEFMYWYPIDMRASGKDLIGNHLTYLLFNHAAIWPTDTSKWPKGIRANGHLLLNNEKMSKSTGNFMTLEEAIEKFSADGMRLSLADAGDGLEDANFVYAMADAAILRLFTMIEWIKEMIEQRDAGLLRKDAKKFADRVFANEMNSLIAATEQNYEATNFKDALKTGFFEYQAIRDTYRELCAGIDEPMSESLVFRFIETQMLILSPICPHIAEYIWQLLGKDGLIVNAPWPTVDPVDEKLAIGARFITESLAEFRARLKTYMTPKKKALKEIPEVPTEAVIYVAKEYPPWQKTILDILEKQAKANNGALPDNKAISQLIGKEESLKKFAKKAMPFVQMIKERFEQKGVSALASSSPVDQTSILNENIDFIMNALDLDRVTIRHTDEEGIDANIVETTVPLVPMLNFTPNRPTIKLVARNVQICNAMFDVDVPIVNGDSVSMVIRKMRRISKAIKPKFEVSLWRYKNAVWGDRQMISYRNPFEENIQLSDADIFNFEADNKISVTSGSEKFDLGRTIVYKANVPEN
What is the function of this protein?
Involved in protein synthesis (PubMed:23076791).  Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: HIS5_YERPS
Sequence: MDVVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQRELIELIKSCTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKMTDFGLPLPHMGWNQITAQAGNHLFRGIPDGTYFYFVHGYAMPICPNTIAQTNYGEPFTAAVEKDNFFGVQFHPERSGAAGAQLMKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_PECAS
Sequence: MATSLTWHDVLAQEKQQSYFINTLEFVGKERSAGKTIYPPQKDVFNAFRFTELHQVKVVILGQDPYHGPNQAHGLSFSVRPGVPAPPSLGNIYKELASDIPGFEIPRHGFLQSWAEQGVLLLNTVLTVEAGQAHSHANLGWETFTDRVIAALNEQREGLVFLLWGSHAQKKGNIIDPQRHHVLKSPHPSPLSAHRGFLGCKHFSQANQLLEQQGLSAIDWTPRLPEEA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_STRPZ
Sequence: MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDMIHFYSDLNNISFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTNSERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGTTVYIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLVLINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKITVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEADRNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQSLLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: MEND_PROM2
Sequence: MTSSIECKNFLRSLQLLNLLIKIGVQNLIVCPGSRSAPLAIAAGELNKLGLVNIFNSIDERSAGFHSLGISAASGNLSLVITTSGTAVSNLLPAAVEADRSCKGIIFLTADRPLRLKDCGSNQTVNQEDFLSSVCRRVLSTNLNGLHETQENEILNLVRIIEKQISTFPGPIHLNIPIDKPLGISFLNKKNVLEVFKRIYLKKKYIFQEFEIKSDKKKFLEISKSLNLDESGIILVGPYQGSVNDLTSFNKSLERLQEITGWPVFADPVSGVYSDLRGLVVNWELVLRKNKNSINCHQLLRLGPMSSSIDLEKFLINFEGIQILIKEKNYRKLDPIKKSFEYDFGLSNFTTLLIEELSINEKNKKSLIPMALDLIEEGEQIKEILKEKITQDNQITEYMLANRVPKLWPAENPIMLSASSPIRDWLTFSENGTLTRNCFSFRGASGIDGTLSLAVGIARIKNPLLLVTGDLAFIHDINGWLIENSVDMNLTILLIDNNGGNIFNRIYKENLKEDELRKLFLMPKEINWPKLAEGYQVNFKNVANFKKLREALDWSISIQKSVIIKVDIDPENEIFEKNALLEKIIGS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DNAJ_STRT1
Sequence: MNNTEYYDRLGLSKDASQDEIKRAYRKLSKKYHPDINKEPGAEEKYKEILEAYETLSDAQKRAAYDQYGPDGANGFGGQGSFGGFDGGAGFGGFEDIFSSFFGGGATRNPNAPRQGDDLQYRVNLSFEEAVFGAEKEIHYNREVTCKTCSGSGAKPGTSPVTCGRCHGHGVINVDTQTPLGMMRRQVTCDVCHGTGQEIKDPCQTCHGTGREKQSHTVSVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLFVVINVNPSDKFTRDGSTIYYTLNISFVQAALGDTVEVPTVHGNVEMVIPAGTQTGKTFRLKGKGAPRLRGGSQGDQLVTVKIVTPTKLNDAQKEALLAFAKASGDEKVAPQKKGFFNKVKDVLEDL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX21A_CTEON
Sequence: ACVPVYEECGTPKKRCCEERPCK
What is the function of this protein?
Antagonist of L-type calcium channels (Cav1/CACNA1).
What are the official names of this protein?
U3-ctenitoxin-Co1a, U3-CNTX-Co1a, Neurotoxin Oc F29-9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 01 (Tx3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1913_CARHZ
Sequence: MKKTKFLLVAVDILPEAIRKTAEVKELLSKRPELTVNEAVEKVGISRSAFYKYKDGVFPFYHKASGKIITLALNLEHRAGVLSKVLNFIAQYQGNVLTINQNLPLGGIANVTISIETEEMKVSIEELLEALSQMDGVSKVELVGQS
What are the official names of this protein?
UPF0735 ACT domain-containing protein CHY_1913.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: ZSC20_MOUSE
Sequence: MMAVASPPPEPEDLLIVKLEEDSWGSDSRPEKESHSPVPGPEVSRRCFRQFRYRDAAGPHEAFSQLWALCCRWLRPELRLKEQILELLVLEQFLSILPREVQTWVQARHPESGEEAVALVEDWHREAWAAGQQGLELCSEDSRSFEAVQEFQRFQLQPVTHGSEGQPRKQWVENARPDLSKMPPESLKESAVLTPQAPTVPKMASIGDWEVAGKSQETPSPSRQAKKEPCQDPAGGDRGDSACLGVPASKPSATSQQEQGPEIWGLSLINSGNGSAADDSLDSAQDKPVQAVAQADSRAWGEPCQWGAEDMKVSGVHWGYEETKTFLAILSESPFSEKLQTCHQNRQVYRAIAERLRARGFLRTLEQCRYRVKNLLRNYRKAKNSHPPGTCPFYEELEALVRARTAIRRTSGGPGEAVALPRLGDSDTEMDDQDEGSWEPEETVEDCSGSGLAAEESLQGPRIAGGPALLQSRIAGVHWGFEETKVFLAILSESPFAEKLRTCHQNSQIYRAIAERLRALGFLRTLEQCRYRFKNLLRSYRKAKSSCPPGTCPFYEEMDSLMRARTVIRAVEMVGEATGLPGSGQSSTEADDQEAWGEMEDEDAVRLLTPDSQPADAGFELKREEEDQISEQDVLGDLPGALSRYTTKAVCQPCDWGEDHVNGNEGEWRNTWEECSSEEDLEKLIDHQGLYLTEKPYGCDTRAKSFSRKVHFFAPQRTHSSEKPYKCLGSGKSFSDRANLSTHQRIHIGEKPYRCLECGKSFNDPSNLITHQRTHTGEKPYKCGLCWKSFNQSSNLLKHQRVHLGGPPNQRDEPGENFGQSLSYSAHWRRNSTQEGPKEPQNISMGADSPGACHPNSGEKLYSCPECGRCFSKSSALTSHQRIHSGEKPYECAVCGKSFSKSSSLANHRRTHTGEKPHKCADCGKCFSERSKLITHQRVHTGEKPYECPECGKFFRDRSNLITHQRIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTHAGGKAL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 20, Zinc finger protein 31.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_LACH4
Sequence: MKIKDTLNLGKTKFKMRGNLPVREAEWQKQWRENKLYEQRLKLNEGKPRFDLHDGPPFANGNIHMGHALNKISKDIIVRYKNMNGYYAPYVPGWDTHGLPVEQQLAKKGVDRKTMDRAKYRELCRQYAEEQVQKQMTDFKRLGVMADWDHPYITLQHDFEAQEIRVFGEMFKKGYIYKGKKPVYWSWSSESTLAEAEVEYKDVEANSIFVAFPVTDGKGIIDPKDTYFVIWTTTPWTIPANEAICVNPKFDYSVVQVGDKRYVVASGLLDKVAEEIGWDDYKVVQTVKGADMEYMKAKHPIYDKESLVIEGFHVTLDDGTGLVHTAPGFGEDDFNVGQRYNLPIFSPVDAHGCYTDEVPELKGMFYQDVDKLMVQKLKDAGALLKLKIFTHSYPHDWRTKKPVIFRATTQWFASIAPFRDQILDQIEKASFIPSWGKTRLYNMIKDRGDWVISRQRAWGVPLPIFYAEDGTPIVTPETIEHIAKIFEKEGSNAWYTHTAKELLPEGFTSEHSPNGEFTKEKDILDVWFDSGSSWSGVMEKRDGLHYPADLYLEGSDQYRGWFNSSLITSVAVTGQAPYKQVLSQGFVLDDKGHKMSKSLGNVISPNDVIKKMGAEIIRLWVAQADTTSDVAVSMGILQQSAESYRKIRNTFRYMLANTSDFDPKENRVAYDDLRSVDQYMEVKLNDLIKECLAAYDKFDFTTVFKKVFNFISNDLSAFYLDFAKDVLYIEVENSHARRSMQTVIYDAAVKLAKILTPILPHTMEEIWGFLKEDEDYVQLANMPEVENYANHDELLENWAKFMKLRDDVLKALEDARNKKLIGKSFEAAVTIYPDKETKAMLDELDADFREILIVSKLTISDDEAPVDAEQLANAAVVVKHAEGEVCPRCRMIRTDIGADPKLPMLCGRCAEIVEANYPEVVQEGLEK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_CRUWA
Sequence: MNSIKFPVLDRTTKNSVISTTLNDLSNWSELSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKIAREIYKDRIRPQQGNRCFTTNHKFFVVRSPHTGNYDQELLYPPSSTSEISTETFFKYKSPVSSHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CYDB_BACSU
Sequence: MASLHDLWFILVAVLFVGFFFLEGFDFGVGMATRFLGHNELERRVLINTIGPFWDANEVWLLTGAGAIFAAFPNWYATMLSGYYIPFVIVLLALMGRGVAFEFRGKVDHLKWVKVWDWVVFFGSLIPPFVLGVLFTTLFRGMPIDADMNIHAHVSDYINVYSILGGVTVTLLCFQHGLMFITLRTIGDLQNRARKMAQKIMGVVFVAVLAFAALSAYQTDMFTRRGEITIPLAVLIVICFMLAAVFIRKKKDGWTFGMTGAGLALTVGMIFISLFPRVMVSSLHSAYDLTVANASSGDYSLKVMSIAALTLLPFVIGSQIWSYYVFRKRVSHKEPMTY
What are the official names of this protein?
Cytochrome bd ubiquinol oxidase subunit 2, Cytochrome d ubiquinol oxidase subunit II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_PASMU
Sequence: MQPNRPIRQALLSVSDKTGIVEFAQALVQRGVKLLSTGGTAKLLADHGLAVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGTDDEVMSQQGIEGIDMVVVNLYPFAATVAKPNCSLEEAVENIDIGGPTMVRSAAKNHQDVAIVVNNSDFNAILAEMDQHQNSLTLETRFDLAIKAFEHTAQYDAMIANYFGQLVKPYFVAEEEDAEAKCGQFPRTLNLNFIRKQTMRYGENGHQKAAFYVEQDVKEASVSTAKQLQGKALSYNNIADTDAALECVKSFDEPACVIVKHANPCGVALGADILAAYNRAYQTDPTSAFGGIIAFNRELDAKTAQTIIDRQFVEVIIAPTVAEEAKALLKAKKNVRVLECGEWSGTQQRLDVKRVNGGLLVQEADLGMVDLADLKVVSKRQPTEQELKDLLFCWKVAKFVKSNAIVYAKDNQTIGIGAGQMSRVYSAKIAGIKAQDEGLDVAGCVMASDAFFPFRDGIDAAAKVGIQCVIHPGGSMRDQEVIDAADEHNMVMVLTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GBRAL_DROME
Sequence: MCTMPATRDASGSGDASTDLIAARSLSSHQGQRSNLRIFKLLISCCLLMLCIYPNAWPWSIGPGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSRILANTPDAST
What is the function of this protein?
GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel.  May combine with the ligand-gated ion channel subunit Lcch3 to form cation-selective GABA-gated ion channels.
What are the official names of this protein?
Gamma-aminobutyric acid receptor alpha-like, GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila, GRD.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: LSPA_CHLTA
Sequence: MPTRSLPTFLTLLLLASIDWVSKLVVLLKSCQLSPHSSAFLYSYVWGHFSFLIIPSFNEGAAFGLFTQYKIPLLIFRVCVILGLALFLRIKYKSLHRRTRVALTLILAGALGNVGDILLYGKVVDFLSLSYYSWRFPSFNLADAFISIGTLLLIGHLYFTKESKKYF
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPE65_CHLAE
Sequence: MSIQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFRGVEVTDNALVNVYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFGKNFSIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYLNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLITLPNTTATAILCSEETIWLEPEVLFSGPRQAFEFPQINYQKYCGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS
What is the function of this protein?
Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins.  Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore.  Essential for the production of 11-cis retinal for both rod and cone photoreceptors.  Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid.  The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.  The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.  The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT.
What are the official names of this protein?
Retinoid isomerohydrolase, All-trans-retinyl-palmitate hydrolase, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Microsome membrane. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated. Undergoes light-dependent intracellular transport to become more concentrated in the central region of the retina pigment epithelium cells (By similarity).
Protein: RBFA_RALPJ
Sequence: MPKKSGSAAGRNVRIADQIQRDLAELIQREIKNPAMGLVTLQSVTLTPDYAHAKIYFTVLGAEPEVAGAILNEKAGYLHSLLFKRLHIHTVPTLHFHFDGSVERGIEMSRLIDEANATRAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_STRZT
Sequence: MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAEVTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFDKFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKRLGYPLLDEETRVKLLAEDAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_DESAL
Sequence: MKAKEIREMGADEIRRKIDDSTQEMFNLRFQHATGQLENTARLNKTKKEVARLKTILKEVEQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ARSC_BACLD
Sequence: MSKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDISEQTSDIIDPDILHNADLVITLCGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFFQRVRDEIGERIKRFAETGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_GUIAB
Sequence: MEVLMAERPTQVFHNKVIDGTAMKRLISRFIDHYGIGYTSHILDQVKTLGFRQATAASISLGIDDLLTIPSKRWLVQDAEQQSFILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMTPNFRMTDPFNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAIRTSDAGYLTRRLVEVVQHIVVRRTDCGTVRGISVSPRNGMMADRIFIQTLIGRVLADDIYIGSRCIATRNQDIGVGLVNRFITFRAQPISIRTPFTCRSTSWICQLCYGRSPAHDDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIKFNEDLVHPTRTRHGHPAFLCSRDLYVTIESEDIIHNVCIPPKSFLLVQNDQYVESEQVIAEIRARTSTLNLKEKVRKHIYSDSEGEMHWNTDVYHAPEFTYGNIHLLPKTSHLWILLGEPWRSSLGPCSIHKDQDQMNAYSLSVKRRYISNPSVTNNQVRHKFFSSYFSGKNQKGDRIPDYSELNRMTCTGRCNLRYPGILDGNSDLLAKRRRNRVIIPLDSIQEGENQLIPSSGISIEIPRNGILRRNSILAYFDDPRYIRKSSGLTKYETRELNSIVNEEDLIEYRGVKVFWPKYQKEVNPFFFIPVEIHILAESSSIMVRHNSIIGVDTQITLNRRSRVGGLVRVKKKAEKIKLIIFSGDIHFPEKTNKAFRLIPPGGGKKNSKEYKKLKNWLYIQRMKLSRYEKKYFVLVQPVVPYKKTDGINLGRLFPADLLQESDNLQLRVVNYILYYDPILEIWDTSIQLVRTCLVLNWDQDKKIEKACASFVEIRTNGLIRDFLRIDLAKSPISYTGKRNDLPGSGLIYENGSDRANVNPFSSIYSSSKARIQESLNPNQGTIHTLLNRNKESQSLIILSSSNCSRIGPFNDVKSPNVIKESIKKDPLIPIRNSLGPLGTGFPISNFDLFSHLITHNKILVTNYLQLDNLKHIFQILKYYLLDENGKIYNPYSCSNIILNPFNLNWYFLHYNYCEETSTIVSLGQFLCENVCIAKKGPHLKSGQVLILQVDSVVIRSAKPYLATPGATVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRIEGWNKCITRILGIPWAFFIGAELTIVQSRISLVNKVQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDEMSNVFSPGELIGLLRAERMGRALEEAICYQAVLLGITRASMNTQSFISEASFQETARVLAKAALLGRIDWLKGLKENVVLGGMIPVGSGFKTPSSEPNNIPNNIAFELKKENLLEGEMKDILFYHRKFFDSCLSKNFHDTQEQSFF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOZ_PARP8
Sequence: MARITVEDCLKQIPNRFELALAATYRARQLAQGHTPKIESRDKPTVVALREIAAGQVGVEMLKKVPV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: OBG_METC4
Sequence: MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYRYRQHFKAKKGEHGMGSNCHGAKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKGGNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIADAGLVGLPNAGKSTFLATVTAAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVLLHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAAGGKPLVLSAASGQGVQEALRAIQAQLDTQGAEEAEAQPAEPWQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.