PharMolix/UniProtQA huggingface dataset:
Protein: XPOT_DICDI
Sequence: MDEFEKAIIYCFDPNVSEDIKQKALAYTESIKVAPEAWLFCLERLGKTQIVLVKFFCLQVFQEIILHRYETLSKTDRLNLRTGLMNWFRLYLVNNQEESAIKNKYAQVMVLLFKQEYLENWLTFFDDFLSMLSPGNSSIDIFLRICKSIDEEVVSFDVHRSPAELAQNTFIKDTMRENAITKIVASWYEILVHHQSPPLINMTLQNIKTYVGWIDISLIVNDKFIPLFCKYLGVRVVRDEVCDCFKEIINKGMDPFAKLTLIQQLEIKNIINFAQLDDQEFNIRVGALINLTGMEILRSLESIQTLQQEGFDKKFQSGEILLEEMLQLLFRFFNNESNDVSYSVYGLASLYVQKLKNIKVLNEKQIQHITLLVQIVRNKMRYKTSRIEEDDDESDIKFADFRKDLSNLFRNIFRICPEMVGSFIATNIQRIVENKNNNNKNKNTTNSKNGTINNNINKTNNNNNNNTNNINNNTNNINNNTTNNNNNNTNKNNVKNANNIKNNNNEDEEDDDDMSFSDIEVSIYLLFQMGEGISATSEETLKSFEKFFGSMVVVLSQSSISITEHQVVSLIYFETIVRYAKYIPMDEQQYLSSVLKSFLDERGIHNKDALVRSKAGYLLNKLAKYLKVQMFPYINDIIDALKNHLIISYEIQKEVPFEEQLNFYESLGFLIGGANLPIEKEALYIEKILNNPIIKMEEIIAKQLYKGDTKENQFYYTVQLTQLINVIGTFSKGFSSFNATNGQLKPDAYCTYKVYFKRSLESIIQLPSLIPSNEDIKSRTFFYMHRMVDVLGKDLKPLLVKILPILLDHATTIDILLEFLVFYNQLISKYKEELFDVINPTLCPIVDRIYKSLNTTIPPVEHSDAERALNDLKKSYFQLIQALFTHNLASTLTSTLNLPLLFQQVFNTVIGGCQASGSHSESIQKVCFVILKKMIDDYSPGGPHAVNGFQSFIYDQVVPLCFQVPLSDQFNMSDFTSTQILLEIGKSLRAIAQKYGDEFLTYMNTILLPKLNVSQEVINQFIKLLQPSSPIKDFQELLKLFIRQKKGLPIKTSNSNINLNNNNNINNNNNNINNNGHTNGNGVNKNGH
What is the function of this protein?
Mediates the nuclear export of aminoacylated tRNAs.
What are the official names of this protein?
Exportin-T, Exportin(tRNA), tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: APT_BURM1
Sequence: MSHSSSGAPLDPVAFIHSQIRTVPDWPQPGVMFRDITTLLQSPKALRILVDLFVERYVDAKLDYVAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYKTRSESYELEYGSATVEIHEDACKPGDRVIIMDDLIATGGTMMAGRNLLERLGAVVVEGAAIIDLPDLGGSALLRNAGLPVYTVTEFAGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_MANSM
Sequence: MFALFIWSFMAIILGIDPGSRVTGYGIIRQTGRTLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFRPDMFAIEEVFLAKNPNSALKLGQARGTAIVAAVNQNLPVFEYAARLVKQTVTGSGSADKVQVQDMVTRILRLSDKPQADAADALAIAITHAHTIQHSLQVATSAKSTENHEKTTALLRTRYSRGRFRLKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RPOH_RHIRD
Sequence: MARNSLPTITAGEAGLNRYLDEIRKFPMLEPQEEYMLGKRYAEHGDRDAAHKLVTSHLRLVAKIAMGYRGYGLPIGEVVSEGNVGLMQAVKKFDPERGFRLATYAMWWIKASIQEYILRSWSLVKMGTTANQKRLFFNLRRLKGRIQAIDDGDLKPEHVKEIATKLQVSEEEVISMNRRLHGDASLNAPIKASEGESGQWQDWLVDDHESQEAVLIEQDELETRRRMLAKAMGVLNDRERRIFEARRLAEDPVTLEELSSEFDISRERVRQIEVRAFEKVQEAVQKEALEAARALRVVDA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of expression of heat shock genes.
What are the official names of this protein?
RNA polymerase sigma factor RpoH, RNA polymerase sigma-32 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_CUPMC
Sequence: MTRDMPDQLGRETPRDGTVLAFDYGEKKIGVALGNFITRQASALTILPNVTVEARFDAVGELIRQWTPVRLVVGMPVNPEAGPDDEEQPSMRLARRFGNQLNGRFNLPVEWVDERYSSRAAAMAGAKRGALDAEAARIILQQYFDELPL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_HAEDU
Sequence: MKQLMMSDVTPEEIFNQRRQIIKSMGLGIATLGLPNIAFAEENVSELKALTFKAASKSDLALTPENKIIGYNNFYEFGTDKAAPAKFAKDFKTDPWQLEISGEVENPFVLNHQQLFNTFPLEERIYRFRCVEAWSMVVPWIGFELARLVEMAKPSSKAKYVVFHTLYDPEQMPGQKNPLFGGSIDYPYVEALTIEEAMNSLTLLSVGLYGKMLPPQNGAPIRLVMPWKYGFKSIKSIVKISFSETRPKTTWESLAPTEYGFYANVNPNVDHPRWSQGSERVIGAGGLLSVKRQPTLMFNGYEDQVAHLYKDLDLKVNF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: ODPA_DICDI
Sequence: MLSNFLKVNSKALGHIRTFASKSGEIKHNFKKADTYLCDGPSDSTVTNKDELISFFTEMSRFRRLETVCDGLYKKKLIRGFCHLYTGQEAVCAGLESAITKDDHIITAYRDHTYMLSRGATPEEIFAELLMKETGCSKGKGGSMHMFTKNFYGGNGIVGAQCPLGAGIAFAQKYNKTGNVCLAMYGDGAANQGQLFEAFNMASLWKLPVIFICENNKYGMGTSQKRSTAGHDFYTRGHYVAGLKVDGMDVFAVKEAGKYAAEWCRAGNGPIILEMDTYRYVGHSMSDPGITYRTREEVNHVRQTRDPIENIRQIILDNKIATEDQLAAIEETVRDEMEKASEKAIAAPLPQARELFTNVYLQEVPVRGVEFVNSFKP
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SPE11_CAEEL
Sequence: MSDEEIDISTALNNKTTPKKKSLKRNSNSQEGYESPEEREIVYPSVFGAIGTPMAKSDNAKEWDEWKEKERKKDKAEWKRYLRSKWDMTQGHLPLVSDSEFLKGRKEHKEYNSKARMDILDGLDEVNEGFFNCGKGAAMNIRYNDKNVSKKGAKKFVATVETAMKKAGNPTMEQMMTDDLDEDEARAEAEWERQREQRKLASRAYDAAMDEREDDAKYVPWDEYCQEMEELGKELKIGEKHYKKWLEKKMDENKVTHKFNAYQLDLKCLDEDAFSNKKSLKSVVRNVQKFYRKMREPKK
What is the function of this protein?
Paternally sperm-supplied factor required for embryogenesis (PubMed:8565851, PubMed:20971008).  Plays a role in preventing polyspermy possibly by promoting the formation of a continuous and cohesive eggshell chitin layer (PubMed:20971008).
What are the official names of this protein?
Spermatocyte protein spe-11, Defective spermatogenesis protein 11.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Localized to the perinuclear region of sperm.
Protein: MUTS_SYNFM
Sequence: MNKITPMMQQYLEIKEKYPDALLLYRMGDFYEMFMDDAVTASGLLEIALTSRDRQSEVRIPMCGVPYHAAEGYIARLVSAGKKVAICDQVEDPRKAKGLVRREVTRVITPGLVLDAQNLAAKQPNYLAAVSNSTAGERFGLAFLDVSTAEFKMVEIESREALLEELIRVSPRELLLSDDDEHPWAEELPKLYGIALTPLGADRFDGKRAEEALVGHFRVHSLEGFGISGMDLGIRAAGAILAYMQANLLGSCDHITRLLPYSRGDFMIVDEAGVRNLEIFHSQSFQGRKGSLIDILDETKTAMGGRKLQQWLRYPLLDLARINNRREAIAELAANAPMRGETLGLLSRISDVERLNGRNSTGTSTPRDLVALKKSLQNLPALGAALAELTSPRLSELRARWDDLADVADIIERTLLDPPPPGLAAGGVISAGVSEELDHFVRLSRDAKGWMADYEVQQRRDTGISSLKVRYNKVFGYYIEISNANLNSVPEHYFRKQTLVNAERFITEELKTFETQVLQAEEKRLELEQQIFADLRARIAREAGRIQAAADRIADLDCVSALAEVACRYDYCRPVMDESDAIRIRDGRHPVIEHYLKDGTFVPNDLDMDQRDQQVLVITGPNMAGKSTILRQAALIVLMGHIGSFVPASEAHIGLVDRIFTRVGASDDLARGRSTFMVEMQETANILHHATPRSLIILDEIGRGTSTYDGLSIAWAVAEHLHDFQEKGIKTLFATHYHELTELARSRPRVRNFNVAIREWQQEILFFHKLVQGGASRSYGIQVARLAGLPEEVTGRAREILQQLESGHAPFAAAPSGAARRGRPAREKEPGIQMSLFQRSPEWLRDRILALDLDNMTPIAALQNLHALKEQIRGSAGEEPASCASRGKR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL20_NITSB
Sequence: MRVKTGTVRRRRHKKILKQAKGFYSGRRKHFRKAKEQLERSLVYAYRDRKQKKREFRKLWITRINAACRLNDISYSRFIHGLSKAGIELDRKILADMAMNEPEAFKAVVEKAKAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ORN_COLP3
Sequence: MAGNDSNLIWLDLEMTGLEPVEDVILEIAIIITDSELNILAQGPIFAISQTDDVLDNMNPWCIEHHGKSGLTQRCRDSEVSLAHATKESLAFVQEWVPQGKSPMCGNSIGQDRRFINKYMPDFEDHFHYRNLDVSTIKELAKRWKPEVLESVVKTGAHLALDDIKESIAELKVYRELFFKL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_SODGM
Sequence: MQVILLDKVANLGGLGEQVNVKAGYARNYLVPQGKAVPATKKNVEYFEERRAELEAKLAETQAAAEARAAKINELGIVTIPSKAGDEGKLFGSIGTRDIADAITAAGINVSKSEVRLPNGVLRTTGDHDVSIQVHSEVFASLNVVIVPEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RCRO_LAMBD
Sequence: MEQRITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTINADGSVYAEEVKPFPSNKKTTA
What is the function of this protein?
Plays an essential role in the switch from lysogenic to lytic state and in fine-tuning the lytic phase activation.  Mediates the de-repression of the lytic promoters from repression by cI at an early stage of prophage induction.  Turns down the expression of the transcriptional activator cII, a factor that initiates the expression of repressor cI, the major component promoting latency.  Additionally, cro is able to directly bind to the promoter region of cI thereby preventing the transcription of cI repressor.  These two mechanisms ultimately lead to a strong decrease in the amount of cI that will become unable to maintain the latent phase, allowing the transition to lytic growth.  Low level of Cro also stimulates the lytic promoters while cI repressor is still present (PubMed:29158090).  Cro-mediated up-regulation of pR and pL ultimately leads to its own increased expression and to a successful switch to lytic growth (PubMed:29158090).  The second function assigned to Cro is the fine-tuning of the lytic phase activation.  Indeed, cro initially diminishes the strength of activation by turning down the expression of lytic genes as well as its own expression.
What are the official names of this protein?
Regulatory protein cro.
Protein: CODY_CLOK5
Sequence: MSTLLDKTRKLNKILQKSGVEPVVFDDICKILSEVLGCNVYVISRKGKVLGYNFPDGFECSTVKNKIISEMRFPEQYNNKLLNAHETLPNLSNHGICVFEDGTPCDLEDKVTTIVPIIGNRERLGTLLLASFGEKFTDEDLVLGEYSATIVGLEILKSKNDEIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGKEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTHIKILNDKLLDELKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_SHIB3
Sequence: MKRMIALDGAQGEGGGQILRAALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGAVRGGEYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGLA_VIBVU
Sequence: MVNQTHEFLLEMTGVSKEFPGVKALDKVNLNVRPHSIHALMGENGAGKSTLLKCLFGIYEKNEGNILFLGKEVNFTSSKEALESGVSMVHQELNQVKQCSVMDNIWLGRYPKKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSVSQMQMVEIAKAFSYDAKIVIMDEPTSSLTEKEVSHLFTIINKLKEKGCGVVYISHKMEEIFAICDEITILRDGQWVDTRPLKGLDMDQIIAMMVGRELTHRFPEKTNTPKDVILEVENLTALNQPSIQDVSFELKAGEILGVAGLVGSRRTDIVETIFGVRERSEGHIRLHGREMKNRDAHEAINNGFALVTEERRSTGIYGNLDITFNALVANVDEYKTQMGLLSDKKMKSDTQWVIDSMRVKTPSHQTHISSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLILELAKKNKGIIIISSEMPELLGITDRILVMSNGRAAGIVNTKETSQNEILELASRYL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RRF_XANOR
Sequence: MLTQIKQDAQTRMTKSIDALRHSLTTVRTGRASPALLDGIKVKAYGTDTPLNQVASISVSEGRSLVISLFDKGMIKDVEKAIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARGAEDDIQKLTDKAIKDVDEVVKAKEQELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCGRX_HUMAN
Sequence: MGCCGCGGCGGRCSGGCGGGCGGGCGGGCGGGCGGCGGGCGSYTTCR
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Small cysteine and glycine repeat-containing protein 10, Keratin-associated protein 28 family pseudogene 2.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 28 family.
Protein: PLYF_ASPTN
Sequence: MRSTAAVLSILLPGALACLGYEGGVPKPTAHYSNSKVIEIAAGQVFDAGWAKYDRGSGACSGDSEGSWQDAVFYLHSGATLKNVIIGKDQAEGVHCDGPCNLEFVWFEDVCEDAITIKNDKAGQETWIVGGGAYHASDKIVQHNGCGTVNIINFYAEDYGKVYRSCGNCSSQCKRNVYVEGVTARDGGEVVGINSNYGDTATLKNVCTDASHPCVLYKGCAGGCEPSKVGYCSG
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase F.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_PARUW
Sequence: MSLDKGTKEEITKKFQLHEKDTGSADVQIAILTERITELTEHLKRAPKDHGSRLALLKLVGQRRRLLDYLNSTDTKRYQTLINKLKLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PLPP3_RAT
Sequence: MQSYKYDKAIVPESKNGGSPALNNNPRKGGSKRVLLICLDLFCLFMAALPFLIIETSTIKPYRRGFYCNDESIKYPLKVSETINDAVLCAVGIVIAILRIITGEFYRIYYLKEKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQNYRCRGEDSKVQEARKSFFSGHASFSMFTMLYLVLYLQARFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSLPAPAIRREILSPVDIMDRSNHHNMV
What is the function of this protein?
Independently of this phosphatase activity may also function in the Wnt signaling pathway and the stabilization of beta-catenin/CTNNB1, thereby regulating cell proliferation, migration and differentiation in angiogenesis or yet in tumor growth.  Also plays a role in integrin-mediated cell-cell adhesion in angiogenesis.
What are the official names of this protein?
Phospholipid phosphatase 3, Differentially expressed in rat intestine 42, Dri42, Lipid phosphate phosphohydrolase 3, PAP2-beta, Phosphatidate phosphohydrolase type 2b, Phosphatidic acid phosphatase 2b, PAP-2b, PAP2b.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: ISPH_RALSO
Sequence: MSTTENAAIEPVTGADAEVLLAQPRGFCAGVDRAIEIVERALQRFGAPIYVRHEIVHNAYVVSDLRSKGAVFVQELDDVPVGGTVIFSAHGVSRAVRQAAEARGLRVFDATCPLVTKVHVEVSKMRTQGFEIIMIGHKGHPEVEGTMGQADDGMLLVESVDDVARLAVKDPARLAYVTQTTLSVDETQEIVAAIKARFPAVHEPKKQDICYATQNRQDAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKLGVPAYMVDTPEQVRPEWLAGKRRVGLTAGASAPEELAQSIVDRLRALGARSVRPLDGIQENMSFPLPRGLQIN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FB111_ARATH
Sequence: MGDWSKLPEELLGLIALRLYSVIELIRFRSICKSWRSSASGVNKNHSLSSPLIYFKPLQIILARAQANGQILSKYHGTVLSRATFFRVTLASSPDQGWLIKSDTDLKYRNFHLLNCLSRKALGRSRKLISLSEFIVSEIQESYAVVGRRTRETASEFKRVFLVRVQGGDHRVLVIGIDGKIRFWKGGIWNGIKKQVAQFSDFVLDEGLTYAVDTKGIMWWISSAYDIIRYGTKLHENITNGSCGEKRFVRCRGELYIVDRLIDENLLKRKADSYDDNAIVHFRNADYTNADLWEDGNGNDDFFAAQAHRFIHVLHDNLGNVSCKPFERDPPKTIGFKVYKNDEELLKWVEVKSLGDKAIVIATDACFSVSAHEFYGCLPNSIYFTDKKEEEVKVFKLDDGSITTMSESEQSCFQMFVPSFL
What is the function of this protein?
Involved in heat stress response.  Contributes to recovery from heat stress.
What are the official names of this protein?
F-box protein At2g17690, Protein SUPPRESSOR OF DRM1 DRM2 CMT3.
Protein: RS17_SINMW
Sequence: MPKRILQGTVVSDKNDKTVVVRVERRFAHPILQKTVRRSKKYKAHDESNQFKVGDLVSIEECAPISKDKRWTVVSAQS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RED_RAT
Sequence: MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEPMDVDKGPGSAKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKRPKY
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome.  Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species.  Required for normal mitotic cell cycle progression.  Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint.  Required for normal accumulation of SMU1.
What are the official names of this protein?
Protein Red, Cytokine IK, IK factor.
What is the protein family that this protein belongs to?
Belongs to the RED family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Predominantly present throughout the nucleoplasm during prometaphase, metaphase and anaphase. Is also detected in nuclear foci that are not identical with Cajal bodies. Starts to accumulate at chromosomes during telophase, and is nearly exclusively associated with chromosomes in newly divided cells. Colocalizes with MAD1L1 at mitotic spindle poles during metaphase and anaphase.
Protein: RL11_COLP3
Sequence: MAKKVQALIKLQVAAGAANPSPPVGPALGQHGVNIMEFCKAFNAKTDSLEKGAPVPVVITVYSDRSFTFETKTPPASFLLKKAAGIKSGSGRPNTDKVGTVTTAQLEEIVKTKEPDLTAGSLEAAVRTIAGSARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.