PharMolix/UniProtQA huggingface dataset:
Protein: LIPL_PIG
Sequence: MESKALLLVALSVWLQSLIVSREGLATADRISGGRDFTDIESKFALRTPEDTVEDTCHLIPGVTESVANCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQQHYPISAGYTKLVGQDVATFIDWMAVEFSYPPNNVHLLGYSLGAHAAGIAGSLTKKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRAQMPYKVFHYQVKMRFSGTESDTHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWVSDSYFSWSNWWSSPGFAIEKIRVKAGETQKKVIFCSREKKSHLQKGKSSVVFVKCHDKSLNRKSG
What is the function of this protein?
Key enzyme in triglyceride metabolism (By similarity).  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (By similarity).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells. Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non- coated endocytic vesicles.
Protein: P5CR_PSEAE
Sequence: MSTPRIAFIGAGNMAASLIGGLRAQGVPAAQIRASDPGAEQRAKIAGEFAIDVVESNAEAVADADVVVLSVKPQAMKAVCQALAPALKPEQLIVSIAAGIPCASLEAWLGQPRPVVRCMPNTPALLRQGASGLYANAQVSAAQCEQAGQLLSAVGIALWLDDEAQIDAVTAVSGSGPAYFFLLMQAMTDAGEKLGLSRETASRLTLQTALGAAQMALSSEVEPAELRRRVTSPNGTTEAAIKSFQANGFEALVEQALNAASQRSAELAEQLGQ
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_MYCTU
Sequence: MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_CHRSD
Sequence: MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEAVFCYEGEGEVETLADGKIHPIKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVHREDGSYAPVD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: RS11_ONYPE
Sequence: MARKKTTKRKVKKNVPLGIAHIHTTFNNTIVTITDLNGNAVTWSSAGALGFKGSRKSTPFAAQLAAEAVAKAAMEHGMVKVETFITGPGPGREAAIRSLQAAGLEITAIKDVTAVPHNGCRPPKPPRG
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MSCL_STAA9
Sequence: MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVVEENVVLLTEIRDLLREKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISC1_VERDV
Sequence: MSSFRSMLGVPPSTASTQDSVLVIIDAQGEYAEGKLKISNIEASRPNISSLLEKYRAANAPIVHVVHETPAGAPLFTQGTKLAEIFDELTPKEGEAVVTKHHPGSFADTNLQEILEKSGKKKIVLVGYMAHVCVSTTARQGAQRGWDVIVAEDAVGDRDIPGVDAAQLVKVALAEIADVFGTLVSSKDIN
What is the function of this protein?
Secreted isochorismatase required for full virulence of V. dahliae (PubMed:25156390).  Suppresses salicylate-mediated innate immunity of the host by disrupting the plant salicylate metabolism pathway via hydrolysis of its isochorismate precursor (PubMed:25156390).
What are the official names of this protein?
Secreted isochorismatase effector Isc1.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Lacks a signal peptide and uses an unconventional secretion pathway for delivering effectors which plays an important role in host-pathogen interactions.
Protein: ATPA_STAAB
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYAGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y371_MYCPN
Sequence: MRIEAANLAGSLWICSVVNHGVQGVGVPSWVPDPELEGAVPKSSALSWTCWLLLEPRLIGALARLLVSSSIWPLSSESDFFFTATCNALTLVSPDEPHVGWIGQIQMWLKNQWPQRPGVFHCSSRCPPRRSSPSSQTLPRWWKYFDHSRFAAVVSPTPFATAHSTPRCAARVKRQTGRDWRGLAPPRRGPCFWPRFTVGVQPHSNQSRQRG
What are the official names of this protein?
Uncharacterized protein MPN_371.
Protein: FADR_ECO8A
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB1_MESAU
Sequence: MALRVTRNTKLNTENKAKVSMAGAKAVPVTLAAASKPGLRPRTALGDIGNKVSEQAQARLPLKKELKTSVTGKVSAKIPPPKPLEKVPPVSEPEVELAETHEPEPVMDEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDADDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLLGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRTSKIGEVDVEQHTLAKYLMELTLLDYDMVDFAPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNHGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVAKA
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: MOT13_MOUSE
Sequence: MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTEDAAVGGPGAQITSLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASSTLVVLAVAYGFTSGALTPVAFSVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCISVSTSRPQDLVIEASDTKIPLPKEEGLGEN
What is the function of this protein?
Proton-linked monocarboxylate transporter.  May catalyze the transport of monocarboxylates across the plasma membrane.
What are the official names of this protein?
Monocarboxylate transporter 13, MCT 13, Solute carrier family 16 member 13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PDUK_SALTY
Sequence: MANKEHRVKQSLGLLEVCGLALAISCADIMAKSASITLLALEKTNGSGWMVIKITGDVASVQAAITTGAHFAEQWNGLVAHKVIARPGEGILLAETPSPSVIEPEPEASEIADVVSEAPAEEAPQESELVSCNLCLDPKCPRQKGEPRTLCIHSGKRGEA
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Bacterial microcompartment shell protein PduK, Propanediol utilization protein PduK.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: BSC5_YEAST
Sequence: MQESKEPQNKFEGCQRISSSSSTLFGGTSFEEPRCGTSQGKEEDAFACNNGDHCSSITNVQEDDFVLPELLPSFEMYENLLSNIPQSSFDTYFPENPPFYEVASRNQSIPSEGESGNDMRILTGDIVGPDNHEVTVDGRRFASGPAESQIRNYDDTKGIPVENIYALPRIKTPIATELYVTKTAPKFGQLPKHESMLREYTSGDIIHGYFTVENKSTKPIKFDMFYLTLEGTTSSKTQSPFGIQKTTERILRMVDMAASWSYNHEDVNTGEDLCGFFDSIDKTSFGLPNSRILNPGDKRKKFFTFKIPNQLLDVTCKHGHFSHSLLPPTLGFDRPSSSHPELSTLKFSESLGYGRLSERGSSLWLNDSSSGSLINYSINAMIVGKDVASGRVCLMSEKKYSIRIVPFGFQNNPISREKCLKDLEDFDIEIANRLGMIEKVFSKIERAIPIHKEDIQEANRSDQLSPLRGKYEWNAVAGNTENGTLKKKH
What is the function of this protein?
May be a component of the ubiquitination pathway.
What are the official names of this protein?
Bypass of stop codon protein 5.
What is the protein family that this protein belongs to?
Belongs to the BUL1 family.
Protein: PQQA_ROSDO
Sequence: MAWTKPIIREIECGMEINMYGPENEDRHDDRDDLF
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: A32_LOXLA
Sequence: ADNRRPIWNLGHMVNAVKQIPTFLNDGANAIEADITFKGAVPTYSYHGTPCDFGRDCIRWEYFDVFLRTLREYTTPGNSKYREKFILFVLDLKTGSLNNHEVRKAGENVAKGLLENYWNNGNNGGRAYVVLSLPDIAHYEFIRTFKEVLKTAGHENLLDKVGYDLSGPYWPSLPSLDSVHEAFKKAGVDGHVWLSDGLTNWAKLGDMARLKEIIKSRDSENGFISKVYYWSVDKYSTTRTALDVGVDGIMTNYPYVIIDVLNENGYKDKYRLATYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (228. 2 U/mg) (PubMed:16759681).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).  Is lethal to mice (PubMed:16759681).
What are the official names of this protein?
Dermonecrotic toxin LlSicTox-alphaIII2, Ll2, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 2, SMD 2, SMase D 2, Sphingomyelinase D 2.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AAP_AAV2S
Sequence: METQTQYLTPSLSDSHQQPPLVWELIRWLQAVAHQWQTITRAPTEWVIPREIGIAIPHGWATESSPPAPEPGPCPPTTTTSTNKFPANQEPRTTITTLATAPLGGILTSTDSTATFHHVTGKDSSTTTGDSDPRDSTSSSLTFKSKRSRRMTVRRRLPITLPARFRCLLTRSTSSRTSSARRIKDASRRSQQTSSWCHSMDTSP
What is the function of this protein?
Plays a role in capsid assembly.  Promotes the transport of unassembled capsid proteins into the host nucleolus for capsid assembly.
What are the official names of this protein?
Assembly activating protein AAP.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: CLPS_ECO55
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: SYR_STACT
Sequence: MNIIDQVKQTLIEEITASVKAAGLAEEVPEVKVEIPKDPKNGDYSTNIAMVLTKIAKRNPHEIAQAIVDHLDKSKANVEKIEIAGPGFINFYLNNQYLTAVIPEALEKDKDFGRNEDPKHQKVLVEYVSANPTGDLHIGHARNAAVGDTLSNILDAAGYDVTREYYINDAGNQITNLAHSIEARYDQAMGKETELPADGYYGKDIINIGKDLAEKRPELKDLPEDERLKVFRQLGVDYEMEKLKKDLADFNTHFDGWFSETTLYDKGEIKKVLELMKENGYTYEADGATWLRTTDFNDDKDRVIIKKDGSYTYFLPDVAYHYDKFHRDGGQDILINLFGADHHGYINRLKASVETYGIDADRLEIQIMQMVRLMQDGEEVKMSKRTGNAITLREIMDEVGIDAARYFLTMRSPDTHFDFDMELAKENSAENPVYYAQYAHARISSILKQAGERGITPSENADFSVITNDKAIDLLKKVAEFEPMIESAAEHRAPHRVTNYIQELASAFHKFYNADKVLTDDEKKTQAYVSMIAAVQITLRNALALVGVSAPHNM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_SYNAS
Sequence: MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNADNAQFIFVDTPGIHSASTPLNRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLKESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPISALTGEGIPLLLDELWKYLPEGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISATINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLREFGYNE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: PYRE_YERPS
Sequence: MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLGRFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVIRYLEDKPEMAEHLVAVRQYREQYGVTL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MUTS_LEVBA
Sequence: MTKTSTTPMMEQYQKIKDQYPDAFLFYRLGDFYEMFNEDAVKGSQLLELTLTTRSHSAKNPIPMCGVPHKAVQSYIDILVDQGYKVAICEQMEDPKLAKGMVKREVIQLVTPGTQTDTGAAGAKRNNYLTALTLADSGEYGLAYTDLSTGELKAAAITGEDAVLNELMSLQTKEVVVDTTVAEGLRQRMKQLGMMISTQDAIQTSSEISYVEQDLTTDLLRQVVGVLVTYVTVTQKRSLAHLQRAVVYQPTAFLKMDHASQTNLELTQNLRTKKKSGTLLWLLDETKTAMGGRLLKQWLDRPLIDRQQIENRQARVAALLDHYFERNSLQEELVKVYDLERLAGRVAFGSVNGRDLIQLQTSLEQVPQIQHTIEELDEPVFDTTLAGLDPVSDVADAIRAAIVPEPPLSVADGGVIRDGFNAQLDEYRDAMRNGKTWLAELEAHEREVTGINNLKIGYNHVFGYYIEVTKVNLSKLPADRYERKQTLTNAERFSTPELKEKERLILEAEEKSVALEYKLFVELREQVKAAITRLQKLAAVIASLDVLQSFAVVSEDYHFVQPKLVSGHQLKITQGRHPVVEKVLGRQSYVPNDVTMDDQTNILLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAEAAEMPIFDQIFTRIGAADDLISGQSTFMVEMQEANRALSHATANSLILFDEIGRGTATYDGMALAQAIIEYVHNRVHAKTLFSTHYHELTALDESLKQLKNVHVGAVERDGDLVFLHQMQPGPADKSYGIHVAKLAGMPTKLLQRAEVILTDLEQSAANQPAAAASQSSSAPAESAQAPVSDSVVAQDVAASAPEPQEKATAISETDQQLSLFSDAPELSPAQAKVLEQISQLNLMGMTPMAIMNQVYQWQQKLTK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YCF24_PORPU
Sequence: MVNTQNQISQTSDLDYIVNQPYKYGFTTSVESEQFPRGISREVVKLISKKKNEPEYLLNFRLKAYEKWTKMKNPKWAHLKHPNIDFNSIIYYAVPKLKKELNSLDEVDPEILDTFNKLGISLNEQKRLSNVAVDAVFDSVSIATTFKKELAEAGVIFCSISEAIRNYPDLIQKYLGTVVPSGDNYFAALNSAVFSDGSFCYIPPDTVCPLELSTYFRINNEESGQFERTLIVADRGSKVSYLEGCTAPQYDTNQLHAAIVELIALDDAEIKYSTVQNWYAGNKDGKGGIYNFVTKRGLCSGKNSKISWTQVETGSAITWKYPGCILAGDNSQGEFYSVALTNNYQEADTGTKMIHIGNNTKSKIISKGISAGKSKNSYRGLVKIGPQSFNSRNYSQCDSLLIGQSSQANTFPYIQVQNPTAKVEHEASTSKISEDQIFYFLQRGINLEESVSLMISGFCKDVFNELPMEFAVEADRLLSLKLEGTVG
What are the official names of this protein?
UPF0051 protein ycf24, ORF487.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TYW3_AERPE
Sequence: MGSIEEVLLEERLIGYLDPGAEKVLARINRPSKIVSTSSCTGRITLIEGEAHWLRNGARVAYKTHHPISRSEVERVLRRGFTNLWLKVTGPILHLRVEGWQCAKSLLEAARRNGFKHSGVISIAEDSRLVIEIMSSQSMSVPLVMEGARIVGDDALDMLIEKANTILVESRIGLDTFSREVEELVECF
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase, tRNA wyosine derivatives biosynthesis protein Taw3.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: BSK5_ARATH
Sequence: MGPRCSKLSLCWWPTHLKSTHNEASDLDNGTDDLPSFTEFSFDQLRAATCGFSTDSIVSEHGVKAPNVVYKGRLEDDRWIAVKRFNRSAWPDTRQFLEEAKAVGQLRNERLANLIGFCCEGDERLLVAEFMPFETLSKHLFHWDSQPMKWSMRLRVALYLAQALEYCSSKGRALYHDLNAYRILFDQDGNPRLSCFGLMKNSRDGKSYSTNLAFTPPEYLRTGRVIPESVVYSFGTLLLDLLSGKHIPPSHALDLIRGKNFLMLMDSCLDGHFSNDDGTDLVRLASRCLQYEARERPNVKSLVSSLAPLQKETDIPSHVLMGIPHGAASPKETTSLTPLGDACSRHDLTAIHEILEKVGYKDDEGVANELSFQVWTDQIQETLNSKKQGDAAFKGKDFVTAVECYTQFIEDGTMVSPTVFARRCLCYLMSNMPQEALGDAMQAQVVSPEWPTAFYLQAAALFSLGMDKDACETLKDGTSLEAKKHNNRN
What is the function of this protein?
Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1 (PubMed:18653891).  Involved in abiotic stress tolerance.  Required for salt stress and abscisic acid-mediated drought stress tolerance (PubMed:22982312).
What are the official names of this protein?
Serine/threonine-protein kinase BSK5, Brassinosteroid-signaling kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYS_RICCN
Sequence: MLNIKWIRENKELFDEKLSQRFIEPMSSKIAMLDGEKRKITSLIQEFQHARKVKSKILGNMASKSGEEFEGLQRDVKHINEKLEALEQDLNNNNELNELLNMFPNIPDDEVPYGMDESMNKLVRTYGETNPNALNKQHFELGIKLNLMDFEQTAKISGTRFVTLKGDLAKLERALINFMIDVHTKEWDFFEISPPVLVRDNAMYNAGQLPKFAEESFATTNGYRLIPTAEVSLVNMVADTIIPREKLPIRYVAYTPCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESTNEHEYITNASETILQKLNLPYRVMLLCTGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNEDGSITIPDVLINYMGGLQKIIAYSE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRY7_HUMAN
Sequence: MATSVLCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIF
What are the official names of this protein?
SPRY domain-containing protein 7, Chronic lymphocytic leukemia deletion region gene 6 protein, CLL deletion region gene 6 protein.
Protein: Y4241_BACCQ
Sequence: MNGIRDVVKEEQPRERLLLEGAGSLSNRELLAVLLRTGSKDETVLKLSDKILHHFDGLRMLKDATLEELVSIHGVGVAKASQLIAAFELGRRMVRLEYQNRYSIRSPEDCARYMMEEMRFLQQEHFVCLYLNTKNQVIHRQTIFIGSLNSSIVHPREVFKEAFRRAAASIICLHNHPSGDPAPSREDIEVTKRLVECGRIIGIEVLDHIIIGDHKFVSLKEKGHI
What are the official names of this protein?
UPF0758 protein BCQ_4241.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: Y1573_METJA
Sequence: MVMLFPDYIRDVNQMKSSLSFLDKIEEDDLAISIYRDRKLSRKELFPIYLGATTHLHKECY
What are the official names of this protein?
Uncharacterized protein MJ1573.
Protein: CTAA_PELUB
Sequence: MFVNSDNYIKYLKLWLITLFSLIVLMVAVGGLTRLTDSGLSITAWELFTGILPPMNINEWNFYFTEYKKIPEYKNINYGMSLDEFKVIFYWEYAHRLLARFVGLFTLVPLLFFTLYFKKTLHYSNKYYWIFFLVCLQGFIGWYMVSSGLIENNDVSHFRLSIHLSLALFILCLIFWYILDIHKIKKFENKIPNLFLLFILKLIVLQIVLGAFLSGLDGGLIYNSWPDMNGSFFPNDVSYGDLITTQLFNNPSIIQFLHRSTAYLLLFFIIILNFIYFKKQYDFKYVLFFDVAILFQIFLGIITLISGVEITYASLHQLGSILVLSSYFLILYKNSN
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.