PharMolix/UniProtQA huggingface dataset:
Protein: TXBJ7_LYCSI
Sequence: MKLIIFTGLVLFAIVSLIEAEEESGRACILLYGECTKATGSCCSNLIYDCYRKLKKGVQIARQCFCSEKDVIYKKDI
What are the official names of this protein?
U11-lycotoxin-Ls1c, Toxin-like structure LSTX-J7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 10 (U11-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TPS2_SORBI
Sequence: MALTPSVCSISDVQGLQKDRTFHPSLWGDFFLTYQPPTAPKHAYMAERAEVLKEEVRKMVKSANEIQNILDLILTLQRLGLDNHYENEINELLSFVHDSDYDDKDLNLVSLRFYLLRKHGYDVSSDVFKCFQDKEGNFVVKDTKSLLSLYNAAHLRIHGEEVLDEAIIFTRGKLESVLDSLETTLADEVTLALQTPLFRRVRILETRNYIPIYEKEVARNEVILEFAKLNFNLLQLLYCEELKMITLWWKQLNVETNLSFIRDRIVEMHFWMTGACSEKKYSLTRTITTKMTAYITILDDIMDTHSTTEEAMLLAEAIYRCEENAAELLPEYMKDFYLYLLKTFDSVKHELGPNRSFRVFYLKELLKILVRGYSQEIKWRDEHYVPETIDEHLEVSKATVGAFQVACSSFVGMGDIITKEILDWLLSYPKLLKSMTTFVRLSNDIASTKREQTGGHHASTVQCYMMQHGTTIHDACEKIKELTEDTWKDMMKLYLTPTEQPKVIIQTVLDFARTAEFMYKKTDAFTFSHTIKDTIALLFVEPTLV
What is the function of this protein?
Sesquiterpene synthase converting farnesyl diphosphate into beta-sesquiphellandrene and six minor products, zingiberene, 7-epi-sesquithujene, sesquisabinene A, (E)-alpha-bergamotene, (E)-beta-farnesene and beta-bisabolene.  Can also accept geranyl diphosphate as substrate, producing nine monoterpenes, with myrcene and limonene as the major products.
What are the official names of this protein?
Beta-sesquiphellandrene synthase, SbTPS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLCL2_MOUSE
Sequence: MAECGRGAAGGALPTSPSPALGAKGALKAGAGEGGGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARTSPGRGPLGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWISQMFSEIDVDGLGHITLCHAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEITKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNVGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVNQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNNPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMMQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENSEAQKPRRSLEAIPEKASDENGD
What is the function of this protein?
May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum.
What are the official names of this protein?
Inactive phospholipase C-like protein 2, PLC-L(2), PLC-L2, Phospholipase C-L2, Phospholipase C-epsilon-2, PLC-epsilon-2.
What are the subcellular locations of this protein?
Cytoplasm. Note=Predominantly localized to perinuclear areas in both myoblast and myotube C2C12 cells.
Protein: LEU3_SYNC1
Sequence: MKKEFKLAVLPGDGIGPEIMAEAMKVLDAVEQKFQVRFERQFANVGGAAIDRDGKALPDATVEICQASDAILFGSVGGPKWDTLPAEERPERGALLPLRRIFGLFCNLRPAIVFPALTSASSLKEEVIAGGFDILVVRELTGGIYFAQPKGVEGEGGERRGFDTMAYTDAEVERITRVAFDAARKRGKKLVSIDKANVLSTSVLWREVVERVSADYPDVVLSHMYVDNAAMQLVKAPKQFDVLLCPNMFGDILSDEAAMLTGSLGMLPSASLAEGSFGMYEPAGGSAPDIAGKNIANPVAQILSAAMLLRYSCGLADAADAVEKAVENCLAAGLRTGDIYQDADGEQLVSTSAMGDAVVAELIKS
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_GEOKA
Sequence: MALKYPSGKEYRGNKPNAARRPAADYANRGMTLEDDLNATNEYYRERGIAVIHKKPTPVQIVRVDYPKRSAAVITEAYFRQASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQIRHMEQVVAHGGICFAILRFSLLNETYLLDASHLIAWWNKQEAGGRKSIPKQEIERHGHSIPLGYQPRIDYISVVDNVYFTR
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P14_BPPH6
Sequence: MATLQDVHLRVNDRVTPVYFTARSFLLVSPKRAGQATFLAREEGTDNPVVTCHVSDFYKDGV
What is the function of this protein?
Needed for optimal phage development.
What are the official names of this protein?
Protein P14.
Protein: STRP1_DANRE
Sequence: MDGVGLCANNKQKQNQMLPNKMRGEFTRNQRKDSEGLSEAPDLEFEYSDADKWTAELSELYSYTEGPEFLLNRKCFEEDFHTHLPDQKWTELDSVQRRAHAMRLLDGLEVIGRERRLKVARAILYMAQGTFGECSSELEVQHWMRYNVFLLLDVGAFTALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLMVETIQREEPTDSPEWRTIRETFKSELGSPLYNHEPVSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAALGLPPLPEDSIRVVRSMRAASPPASASDLIEQQQRRARREHKALIKQDNLDTFNEKDPYKADDSHEDEEENDDNDNSLEAEPFPLERDEVMPPPIPHPPTERMCFPKGLPWAPKVREKDIESFLESSRSKFIGYTLGNDTDTVVGLPRPIHESIKTLKQHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCATELLYQGILPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISALDFPHCVIHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNSRRYDKNQSNPEFLPVDNCLQSVLGQRIDLPEDFQMNYDLWLEREVFSKPISWEELLQ
What is the function of this protein?
May play a role in the regulation of cell morphology and cytoskeletal organization.  Required in the cortical actin filament dynamics and cell shape (By similarity).
What are the official names of this protein?
Striatin-interacting protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the STRIP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched on the plasma membrane.
Protein: PVK2_ENTSB
Sequence: GASGLISFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, Entsp-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF4EA_DANRE
Sequence: MATAEPETSTNPSNSEEKNEENEQQIVSLEDYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1A, eIF4E-1A, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SCPA_STRS7
Sequence: MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIETLQTMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKALSQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHTVIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVGIEQTSHFGQIVLRKEIQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: UBIE_PSEMY
Sequence: MSDPRKAQEQEPTTHFGFQDVPESQKAEKVAEVFHSVAAKYDLMNDVLSGGLHRLWKRFTIELSGVRPGNRVLDIAGGTGDLTRKFASIVGPTGEVVLADINDSMLKVGRDRLLDKGVAGNVQFVQADAEKLPFPDNHFDVVTIAFGLRNVTHKEDALRSMLRVLKPGGRLLVLEFSKPGNPLLAKVYDTYSFSFMPLAGKLITNDADSYRYLAESIRMHPDQETLKAMMVDAGFERVTYHNMTGGIVALHRGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PTK7_DROAN
Sequence: MAALRISVWILVQALMMALVSSNSSHFLQLPQSQSVVENESVDFECQASTDPSSELHYEWLHNGHRIAYDKRVYQIGSHLHIEAVQRAEDVGDYVCIATSLASGAREASPPAKLSVIYIDSASVQLLGSNRNELLLKCHVEAVSGSDDPLQIEWYRNSAKLSSWQNVQLDQHRLIIRQPSAADDGLYRCTASNAAGRVMSKQGYVYRSSLKCLPRLPRRKNQKLPESWSKEVFLCRGKRGGSGGVEALPSAPEDLRIVQGPASHAIIKEGDPAALTCLYELPAELQNQRIQLRWRKDGKLLRHVELGNSLPLPGISSDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEGYAPINSSPGTLEVIEQLKFVPQPTSKNLELDAPIAKVHCKAQGTPTPQVQWMRDDANTSLPDQVEVDANGTLIFRNVNADHRGNYTCLATNSQGQINATVAINVVVTPKFSVPPVGPIETAEQGNVVIHCQAIGDPKPTIQWDKDLTYLSENNTDRERFRFLENGTLEIRNVQAEDEGSYGCTIGNSAGLKREDVQLVVKTAGDGFPPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNELSTKEAGGDQPDGAANGKGSEQEPCLSKQRNGHGGQSRSKSNGDAQKSDDTACSQQSRASKKSAHIYEQLALPRSGLTELIQIGRGEFGDVFVGKLKASLVATGSPSDKDADTEKQHSNSENGSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQEQQQSDLDQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTASAAATSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHEELTNEQVIQKSQAGTLEWTVAESTPDSLREILLSCWVSNPKERPSFSQLGAALSKAMQSLEK
What is the function of this protein?
Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system.  Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage.  Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase-like otk, Tyrosine-protein kinase-like 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ALPHA_BSMV
Sequence: MASDEIVRNLISREEVMGNLISTASSSVRSPLHDVLCSHVRTIVDSVDKKAVSRKHEDVRRNISSEELQMLINAYPEYAVSSSACESGTHSMAACFRFLETEYLLDMVPMKETFVYDIGGNWFSHMKFRADREIHCCCPILSMRDSERLETRMMAMQKYMRGSKDKPLRLLSRYQNILREQAARTTAFMAGEVNAGVLDGDVFCENTFQDCVRRVPEGFLKTAIAVHSIYDIKVEEFASALKRKGITQAYGCFLFPPAVLIGQKEGILPSVDGHYLVENGRIKFFFANDPNAGYSHDLKDYLKYVEKTYVDIEDGVFAIELMQMRGDTMFFKITDVTAAMYHMKYRGMKRDETFKCIPLLKNSSVVVPLFSWDNRSLKITSGLLPRTLVEQGAAFIMKNKEKDLNVAVLKNYLSAVNNSYIFNGSQVRDGVKIAPDLISKLAVTLYLREKVYRQRENSIISYFEQEMLHDPNLKAMFGDFLWFVPNTLSSVWKNMRKSLMEWFGYAEFDLTTFDICDPVLYVEIVDRYKIIQKGRIPLGEFFDCHEECENYELREKEKNDLAVKMAQKVTGTVTECEKDLGPLVQPIKEILVQLVMPNLVRALCRPRSPTSPLDLKSIPGSTPSHSSSDSEHSMTEEASCTIAGSVPTWEIATRKDLTFQRIDEDMSRRTGMPPRPKVTSSYNMNARAEFLYYQLCSVICERAQILSVIEDFRQNLIFSDKVAVPLNARFYSFQSLRPGWVFKTPSHSEVGHSYAVHFDFKTIGTDLEESLAFCRMVPISWDKSGKYIATTPHFPERHGYYVICDNTKLCNNWLIYNKLVDVYALVADRPLRFELIDGVPGCGKSTMILNSCDIRREVVVGEGRNATDDLRERFKRKKNLNSKTANHRVRTLDSLLLAEGPCVPQADRFHFDEALKVHYGAIMFCADKLGASEILAQGDRAQLPMICRVEGIELQFQSPDYTKTIINPKLRSYRIPGDVAFYLSAKEFYKVKGIPQKVITSNSVKRSLYARGETTPERFVSLLDVPVRKDTHYLTFLQAEKESLMSHLIPKGVKKESISTIHEAQGGTYENVILVRLQRTPNEIYPGGPRSAPYIVVGTSRHTKTFTYCSVTDDKLLLDIADVGGIAHTPIRTFESHIV
What is the function of this protein?
Probably contains methyltransferase and helicase activities (PubMed:2209552).  Methyltransferase displays a cytoplasmic capping enzyme activity (Probable).  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus (Probable).  Helicase region probably exhibits NTPase and RNA unwinding activities (Probable).
What are the official names of this protein?
Replication protein alpha-A.
What are the subcellular locations of this protein?
Host chloroplast envelope. Note=The viral replication sites are located at the host chloroplast membrane.
Protein: YEEX_ESCFE
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAELSKERRDISKKLKVMGEIKNGEAKSE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: NRDR_SHEPA
Sequence: MHCPFCSATDTKVIDSRLVADGHQVRRRRECVQCHERFTTFEGAELVMPRVVKQDGSRQPFDEEKLRGGMLRAVEKRPVSMDQIEQALTKIKSTLRATGEREVKSEMIGNLMMDQLVNLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NUOA1_GEOSL
Sequence: MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKFYIIAMLFILFDIEAVFMYPWSVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 1, NADH dehydrogenase I subunit A 1, NDH-1 subunit A 1, NUO1 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAC71_ARATH
Sequence: MGSSCLPPGFRFHPTDEELIGYYLSRKIEGLEIELEVIPVIDLYKFDPWELPGKSFLPNRDLEWFFFCPRDKKYANGSRTNRATKAGYWKATGKDRKITCKSSHVIAGYRKTLVFYEGRAPLGDRTNWFMHEYRLCDIDDHSQKSPNFKGAFALCRVVKKNELKKNSKSLKNKNEQDIGSCYSSLATSPCRDEASQIQSFKPSSTTNDSSSIWISPDFILDSSKDYPQIKEVASECFPNYHFPVTTANHHVEFPLQEMLVRS
What is the function of this protein?
Transcription factor involved in tissue reunion of wounded inflorescence stems.  Required for the division of pith cells in the reunion process, which is dependent on polar-transported auxin and the wound-inducible hormones ethylene and jasmonate (PubMed:21911380).  Binds to the promoters of XTH19 and XTH20 to induce their expression via auxin signaling.  XTH19 and XTH20 are involved in cell proliferation in the tissue reunion process of incised stems (PubMed:25182467).  Involved in hypocotyl graft union formation.  Required for the auxin- mediated promotion of vascular tissue proliferation during hypocotyl graft attachment (PubMed:27986917).
What are the official names of this protein?
NAC domain-containing protein 71, ANAC071.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB_MYXXD
Sequence: MEARELSLRYGPKTAIHKVSLAILDRRVTALIGPSGCGKSTFLRSLNRMNDLISGTTHSGTILLDGTDIHDRGVDVVDLRRRVGMVFQKSNPFPKSIFENVAYGLRVGGMKDKAELATRVEKSLRGAALWDEVKDRLDESALGLSGGQQQRLCIARAMAVEPEVLLMDEPASALDPIATAKIEELIHELKSTYTIAIVTHNMQQAARVSDRTAFFYMGELVECGPTEQIFTNPREKRTEDYVTGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TERM_BPPZA
Sequence: MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLSAEINIPDLESFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKINAMKDKEYYAGGKPQGTIEQRIAMTSPAHVTGINRPRDFDFSKVRTYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIKSVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF
What is the function of this protein?
Hydrolyzes host peptidoglycans during virus entry.
What are the official names of this protein?
DNA terminal protein, Gene product 3, gp3, Protein p3.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus DNA terminal protein family.
What are the subcellular locations of this protein?
Virion. Note=Associates with the host bacterial nucleoid through its N-terminal region.
Protein: CAPSD_BPE32
Sequence: MANPTLFVSYDQNGKKLSFANWISVLSPQDTPFVSMTGKESINQTIFSWQTDALASVDGNNAHVEGSRAEDGEMKPTVIKSNVTQILRKVVRVSDTANTTANYGRGRELMYQLEKKGKEIKRDLEKILLSGQARTDVLADQYLTNSATDPAVVGLNDTHAARKTGAFQFLCAHGGLAGGVVDKTKNGPADPDTGAVTVKVAQNASNPTTNIGFDEADIFDMTLQLYTAGSEADIIMINPAHAKIFAGLQENTQGSRKRIFENTKQFIYEVNSITDPLGQSYKIIVNRWMPTDAVYFFRSADWTQMVLRAPKRTELAKDGSYEKWMIEMEVGLRHRNPYASGVLFTAAGKVAA
What is the function of this protein?
Assembles to form a prolate capsid of about 145 nm x 44 nm.
What are the official names of this protein?
Major capsid protein, Gene product 11, gp11, Major head protein.
What are the subcellular locations of this protein?
Virion.
Protein: TATB_PARXL
Sequence: MLDLGLTKMALIGVVALVVLGPERLPRVARTAGALFGRAQRYINDVKAEVTREIELDELRRMKSEFEAAATNVETSVQDNLRKHESELNDAWNSGTSVSPSIAGGALEDVGNAGNTSWPGSTPAAGAKRKNWRVRQTAMPTWYKRATTRRTRVQSGAARVARHTPATMRRPTRFF
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS3_METFK
Sequence: MGQKIHPFGFRLSVQKNWSSRWYANSNNFPAMLSSDIKVREFLKKKLAHAAVSKIVIERPAKNAKITIYSARPGIVIGKKGEDIESLRSGLQGLMGVPVHLNIEEVRKPEIDATLIAESIAQQLEKRVMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRADIDYGVAEAKTTYGIIGIKVWVFKGEVFGNKIEQAAQPAEPEKKVRKSGAKNAATS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: VP40_EBOSU
Sequence: MRRVTVPTAPPAYADIGYPMSMLPIKSSRAVSGIQQKQEVLPGMDTPSNSMRPVADDNIDHTSHTPNGVASAFILEATVNVISGPKVLMKQIPIWLPLGIADQKTYSFDSTTAAIMLASYTITHFGKANNPLVRVNRLGQGIPDHPLRLLRMGNQAFLQEFVLPPVQLPQYFTFDLTALKLVTQPLPAATWTDETPSNLSGALRPGLSFHPKLRPVLLPGKTGKKGHVSDLTAPDKIQTIVNLMQDFKIVPIDPAKSIIGIEVPELLVHKLTGKKMSQKNGQPIIPVLLPKYIGLDPISPGDLTMVITPDYDDCHSPASCSYLSEK
What is the function of this protein?
Plays an essential role virus particle assembly and budding.  Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101.  The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding.  May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
What are the official names of this protein?
Matrix protein VP40, Ebola VP40, eVP40, Membrane-associated protein VP40.
What is the protein family that this protein belongs to?
Belongs to the filoviridae matrix protein VP40 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and probably also in multivesicular bodies. These VP40-enriched membrane clusters are then redistributed to the plasma membrane where budding takes place.
Protein: GPMI_PSEF5
Sequence: MTTTPKPLVLMILDGFGHSESHESNAVYAAKKPVLDRLCASMPNGLISGSGMDVGLPDGQMGNSEVGHMNLGAGRVVYQDFTRVTKAIRDGEFFENPTICAAVDKAVDAGKAVHILGLLSDGGVHSHQDHLIAMAELAFKRGAEKIYLHAFLDGRDTPPKSAQSSIELLDETFKTLGKGRIASLIGRYFAMDRDNRWDRVAQAYNLIVDGQGQFNAATAQEGLQAAYAREESDEFVKATTIGEPVKVEDGDAVVFMNFRADRARELTRVFVEDDFKDFERPRQPKLAGFVMLTQYAASIPAPSAFAPGSLENVLGDYLAKNGKTQLRIAETEKYAHVTFFFSGGREEPFPGEERILIPSPKVATYDLQPEMSAPEVTDKIVDAIEHQRYDVIIVNYANGDMVGHSGVFEAAVKAVECLDLCVGRIVDALEKVGGEALITADHGNVEQMSDESTGQAHTAHTTEPVPFIYVGKRALKVREGGVLADVAPTMLKLLGLPKPAEMTGTSILVDPAH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: LEXA_PARXL
Sequence: MTKLTARQQQVFDLIRRAIERTGFPPTRAEIAAELGFSSANSAEEHLRALARKGVIELAAGASRGIRLLAGPEDSPHQFTLPHASIMQLSLPLIGRVAAGSPILAQEHISQHYACDPALFSSKPDYLLKVRGLSMRDAGIFDGDLLAVQKKSEAKDGQIVIARLGDDVTVKRLKRRPNGLELIAENPDYENIFVETGSAEFALEGIAVGLIRPGEF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PYRG_ECOK1
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.