PharMolix/UniProtQA huggingface dataset:
Protein: HEMH_SALHS
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYDC3_PAPSO
Sequence: MGSLNTEDVLEHSSAFGATNPLDPEEFRRQGHMIIDFLADYYRDVEKYPVRSQVEPGYLRKRLPETAPYNPESIETILQDVTSEIIPGLTHWQSPNYYAYFPSSGSVAGFLGEMLSTGFNVVGFNWMSSPAATELEGIVMDWFGKMLNLPKSYLFSGTGGGVLQGTTCEAILCTLTAARDRKLNKIGREHIGRLVVYGSDQTHCALQKAAQIAGINPKNFRAVKTFKANSFGLAASTLREVILEDIEAGLIPLFVCPTVGTTSSTAVDPIGPICEVAKEYEMWVHIDAAYAGSACICPEFRHFIDGVEEADSFSLNAHKWFFTTLDCCCLWVKDPSSLVKALSTNPEYLRNKATESRQVVDYKDWQIALIRRFRSMKLWMVLRSYGVTNLRNFLRSHVRMAKTFEGLVGADRRFEITVPRTFAMVCFRLLPPTTVKVCGENGVHQNGNGVIAVLRNENEELVLANKLNQVYLRQVKATGSVYMTHAVVGGVYMIRFAVGSTLTEERHVIHAWEVLQEHADLILSKFDEANFSS
What is the function of this protein?
Marginally higher substrate specificity for L-DOPA over L-tyrosine.
What are the official names of this protein?
Tyrosine/DOPA decarboxylase 3.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: PMFBP_MOUSE
Sequence: MLKLKGELRTAKGLKNEAGERDRDVSNLNSKLLSLQLDIKNLHDVCKRQGKTLQENQLCVEEAMLKANHNKKQAQTLVFTDNQMDFRVNKQYHLRQLQQLKKKLLTLQQELEFRTQELQASYCSLLQYQSILEKQTSDLLVLHRHCKLKEDEVILYEEEMGNHSKSTGEKLHLAQEQLALAGDKILSLERSLNLYRDKYQTSLSNIELLECQVKMLEGELSGLIGQDPENKGDHPKVRIYTSPCVIQEHQETLKRLSEVWQKVSEQDDLIQELRNKLACSNSLVLEREEALIKLQAEFASYTATHRHPPTSSEDCEDITKILKHLQEQKDSQCLHVEEYQNLVKDLRMELEAVSEQKKKIMKDMMKLELDLHGLREETSCVIEKKDKETVFLQYRLQDLQQQYTESQKLSLKKDKLLQDKDERLHELEKNLMQVQNSLREKEAELEKLQCTTKELDTSLQEARQSTSKIDCEALRAEIQKLKDSLEEAREQLKVSDQNLTQSKEEAHLSASSLEDAHRKIENCLLQDKQKEEVIKDLQSQLHKLQKESSKIEEERKHNRQRLQELSSELSEGQRRLSNAEKEKSLLQKTLDEDEKKIDELFHSTQVSEQKQRELTNSIRKLEEELLEIKGLLEEKREQLKKSKEQEKALEEEIEALRQEAKRKEKMAKEHLRKLDEEKENLQAELTSRSSHLDSSLNKYNSSQKVIQELNAEIARQKDSIMILQTQLDSAIQKEKNCFQNMVSKEAYEELVRKSGNCQDDLTQALEKLTQATSETKSLNRSLQQTQERKAQLEDEIAAYEERMKKLNMELKKLQGFQQQSEQEVHNFDKKLEEMSNQVLQWQRQHQSDLKMLAAKESQLREFQEEMATLRESLLADEKEPYSPPAKLTPKETCRHHRENDQIMNNVEQWAKEQKIANEKLGNKLREQVKYIAKLTGEKDHLHNVMVHLQQENKKLKNEIEEKKLKAGNPRICVKAFPPNKLEPSQKGKLCCALGWRGIPQDLTPKTDHKYMGLPHSSGSSYC
What is the function of this protein?
Required for normal spermatogenesis (PubMed:30032984, PubMed:30298696).  It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, thus maintaining sperm head and tail integrity (PubMed:30032984).  May also be involved in the general organization of cellular cytoskeleton.
What are the official names of this protein?
Polyamine-modulated factor 1-binding protein 1, PMF-1-binding protein, Sperm tail-associated protein.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Localized at the sperm head-tail connecting piece (PubMed:30032984, PubMed:30298696). During spermatogenesis, it is first observed in the cytoplasm of round spermatids, it later appears in the implantation fossa region of the sperm nucleus during sperm head elongation and differentiation, and finally it localizes to the head-tail connecting piece (PubMed:30032984).
Protein: NSCC_NEOFI
Sequence: MAPPLPILIIGAGISGLTTARLLTNSGIPNIVFEASSPDRRQGFAISLREWGYATLLSALGDLPLRSLTRGVAPDREIGGSGWIDQAVWDNGTAKKLFVPDANSSTKEQIVRANRNALRRWIADCGEEELDVRYGHRLKRVEGSLGDVQVEFENGAFYRGLMVVAADGVNSTVRSQVLADVQPEIVPAVLYHGEFQLPRADFDRLFRPHTGESNILAGVGDGFNTPFAVCNMTKTHVHMDWSYSRPAWGSGENDPLYRPNLASEEAKRIPPALVEELASRDLAEPWSLFLNGEAIQHHRVFHWAVRCVSVTQEDMQRAVGRGIAFVGDSWHAMPIFGGEGGNHALADGVELAAAVAAGVAGDLGVAIGNYYDRAWKRSQDAVRRSKQRFYALHRPMAQWRELSQKKPV
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of neosartoricin, a prenylated anthracenone that exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576, PubMed:23368997).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (PubMed:23368997).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (PubMed:23368997).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (PubMed:23368997).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (PubMed:23368997).  There is no gene encoding O-acetyltransferase in the nsc gene cluster; thus, the last step of 2-O-acetylation leading to neosartoricin may be catalyzed by an unidentified O-acetyltransferase (PubMed:23368997).
What are the official names of this protein?
FAD-dependent monooxygenase nscC, Neosartoricin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: ICP0_EHV1V
Sequence: MATVAERCPICLEDPSNYSMALPCLHAFCYVCITRWIRQNPTCPLCKVPVESVVHTIESDSEFKETKVSVDFDYDSEEDEDSFEGQFLAVDSGDAPANISAWNGPMAFVPLNANGTAGAPRLQPLVDWLVERLDQLFETPELALVMRNIVMDTLCEHGCNEEELTRQFWPMFHEDTVPFVTDLIVQAELCVASRPILPIARGRGVEYIDSSSSSSSSEEETDSDIEVDPNNLTDPEDTSDETSTDNSSAQAPRQEDSRPARARPGPPTRGRRRGRRPAAPGPASRRSARLRRRQPRTNSRTNGGDNGEIIDLTLDSDGDTEPADVSGSLNTTDQPVLIPDEEEAAPASPHTSSNSAIICLVSELTPESEEPPRDQPVAPSGSSAGERPMRPRCSLREFARRFMALAPRDSSTSEAAGPSRLGAGPRATEPFSVAVVLVDRSSEGAGLFGGRFAQHVRRRTEDESARRRGNVLLRPRRQSVPPVPYPDIASTSPLIRQGGQRVRDLQRAFQTQPAEPEEMRCPHNCQRYRRNQ
What is the function of this protein?
Evades nuclear antiviral defenses triggered by dsDNA viruses.  Acts during the initial stages of lytic infection and the reactivation of latent viral genome.  Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100.
What are the official names of this protein?
E3 ubiquitin-protein ligase ICP0, Infected cell protein 0, RING-type E3 ubiquitin transferase ICP0.
Protein: NADD_BACAC
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYKLRTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: G3P_BPM13
Sequence: MKKLLFAIPLVVPFYSHSAETVESCLAKPHTENSFTNVWKDDKTLDRYANYEGCLWNATGVVVCTGDETQCYGTWVPIGLAIPENEGGGSEGGGSEGGGSEGGGTKPPEYGDTPIPGYTYINPLDGTYPPGTEQNPANPNPSLEESQPLNTFMFQNNRFRNRQGALTVYTGTVTQGTDPVKTYYQYTPVSSKAMYDAYWNGKFRDCAFHSGFNEDPFVCEYQGQSSDLPQPPVNAGGGSGGGSGGGSEGGGSEGGGSEGGGSEGGGSGGGSGSGDFDYEKMANANKGAMTENADENALQSDAKGKLDSVATDYGAAIDGFIGDVSGLANGNGATGDFAGSNSQMAQVGDGDNSPLMNNFRQYLPSLPQSVECRPFVFSAGKPYEFSIDCDKINLFRGVFAFLLYVATFMYVFSTFANILRNKES
What is the function of this protein?
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process.  During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host F-pilus.  Subsequent interaction with the host entry receptor tolA induces penetration of the viral DNA into the host cytoplasm.  In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal domain.
What are the official names of this protein?
Attachment protein G3P, Gene 3 protein, G3P, Minor coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G3P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass type I membrane protein. Note=Prior to assembly, G3P is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the head side of the filamentous virion.
Protein: PALY_USTMA
Sequence: MAPTADVLPPVEASTRPGLLVQPSDTKLRKASSFRTEQVVIDGYNLKIQGLVASARYGHVPVLDPSAETRKRIDDSVQSLIAKLDRGESIYGINTGFGGSADSRTANTRALQLALLQMQQCGVLPVPSTFPTGEPSSAPFALPLTDTESSLIMPEAWVRGAIVVRLSSLMRGHSGVRWEVLDKMQKLFLQNNVTPVVPVRSSISASGDLSPLSYVAGALAGQRGIYCFVTDGRGQRVKVTADEACRMHKITPVQYEPKEALGLLNGTAFSASVAGLATYEAENLASLTQLTTAMAVEALKGTDASFAPFIHEIARPHPGQIKSAKFIRALLSGSRLAEHLENEKHVLFSEDNGTLRQDRYTLRTASQWVGPGLEDIENAKRSVDIEINSTTDNPMIDPYDGDGRIHHGGNFQAMAMTNAVEKIRLALCAMGKMTFQQMTELVNPAMNRGLPANLASTPDLSLNFHAKGIDIALASVTSELMFLGNPVSTHVQSAEMANQAINSLALISGRQTLQAIECLSMIQAWSLYLLCQALDIRALQYKVAEQLPTLILASLHSHFGEWMDETKQQEIAAQVLKSMSKRLDETSSKDLRDRLVETYQDASSVLVRYFSELPSGGGADPLRNIVKWRATGVADTEKIYRQVTIEFLDNPYACHASHLLGKTKRAYEFVRKTLGVPMHGKENLNEFKGEFEQWNTTGGYVSVIYASIRDGELYNMLSELERDL
What is the function of this protein?
Catalyzes the non-oxidative deamination of L-phenylalanine to form trans-cinnamic acid and a free ammonium ion (By similarity).  Facilitates the commitment step in phenylpropanoid pathways that produce secondary metabolites such as lignins, coumarins and flavonoids (By similarity).
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 385L_IIV6
Sequence: MNISKTKSVSLVYEDLNKIVNEIVSKQFRSRHPDGDSDIDLQHLFSIINLKNPENDNDATNKQFVLTSIRDDTIHVNRKGDIMHGNLDMGGNFFVTNVNDKEMNPPDTHAATVGYVNRKIASYIPKANLNIICSQGFKGKKGITSRTDDIYKFFPAGVVLPTDAIIEKISLTTTNDTVENSKHKLTIKISDPLNSGDVQTETVFEKLGSQLYFSQQFRKPVGNKKISFQLDSFVDSAPVAIFAGESTLTLEISV
What are the official names of this protein?
Uncharacterized protein 385L.
Protein: GPDA_SHEB5
Sequence: MKNSADITVLGAGSYGTALAISLASNGHKTLLWGHDPVHMQTLAQDKCNQAFLPGIAFPDCLQIEADLAKALAASNNVLVVVPSHVFGTVLEQAKPLLRSDARIVWATKGLEPETGRLLQDVARDVLGEQYPLAVLSGPTFAKELAMGLPTAISVAGTCPTFTNYLVELLHSPKRLRVYANDDFTGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELTRLGEALGANAATFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVMTAQAEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYQVLYQGKSPVDAAKELLSREKKSETPAQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORTL_BPMU
Sequence: MGRILDISGQPFDFDDEMQSRSDELAMVMKRTQEHPSSGVTPNRAAQMLRDAERGDLTAQADLAFDMEEKDTHLFSELSKRRLAIQALEWRIAPARDASAQEKKDADMLNEYLHDAAWFEDALFDAGDAILKGYSMQEIEWGWLGKMRVPVALHHRDPALFCANPDNLNELRLRDASYHGLELQPFGWFMHRAKSRTGYVGTNGLVRTLIWPFIFKNYSVRDFAEFLEIYGLPMRVGKYPTGSTNREKATLMQAVMDIGRRAGGIIPMGMTLDFQSAADGQSDPFMAMIGWAEKAISKAILGGTLTTEAGDKGARSLGEVHDEVRREIRNADVGQLARSINRDLIYPLLALNSDSTIDINRLPGIVFDTSEAGDITALSDAIPKLAAGMRIPVSWIQEKLHIPQPVGDEAVFTIQPVVPDNGSQKEAALSAEDIPQEDDIDRMGVSPEDWQRSVDPLLKPVIFSVLKDGPEAAMNKAASLYPQMDDAELIDMLTRAIFVADIWGRLDAAADH
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.  Acts as a linker between the capsid and tail.  Required for attachment of the neck proteins to the capsid.
What are the official names of this protein?
Portal protein, Gene product 29, gp29, Gene product H, gpH, Head-tail connector.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located at a unique 5-fold vertex of the icosahedral capsid.
Protein: PDLI2_MACFA
Sequence: MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQAASPGQTNGDSSLEVLATRFQGSVRTHTESHSSLRSSYSSPTSLSPRAGSPFSPPPFSSPLAGEAAISRSFQSLACSPGLPAADRLSYSGRPGSQQAGLGRAGDSAVLVLPPSPGPRSSRPSVDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGDELYCEKHARQRYSAPATLSSRA
What is the function of this protein?
Probable adapter protein located at the actin cytoskeleton that promotes cell attachment.  Necessary for the migratory capacity of epithelial cells.  Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth.  May contribute to tumor cell migratory capacity (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes at the cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN) (By similarity).
Protein: PLAC4_HUMAN
Sequence: MKELLRLKHCKHLLTTHVHSPWTPSLTLTPSLLTLDTLTHPRHRHSSPWTPHSAPWTPSLTLDTFTHPDTLTHPGHPHSPWIPSLLTLDTLTHPGYPHSSPWTLSLTLTPSILTLDSLTPHPGLPHSSPWTPSLLILDTLTQPGHPHSSP
What are the official names of this protein?
Placenta-specific protein 4.
Protein: ATG5_ORYSJ
Sequence: MAAQRDDEAGWSAEAARRVWGGAVPLQVHLHDADVTTLPPPPPFLTLGPRIGYLPLLVPIIKAHFSSTLPPGIDTVWFEYKGLPLKWYIPIGVLYDLLCADPERPWNLTVHFRGYPSEILTLCDGEDSVKWSYMNSLKEAAFIITGNSKNVMNMSQADQGALWQSVMKGNLDGYMNISTRLKLGPFEEDCLVRTSSVEGQQGSDEPESPGSGKPCRVPVRLYVRSVQEDLYDLEDALPVGDWESISYINRPFEVRREEGRSYITLEHALKTLLPEFFSSKASRIPDDSETAPQAPDSAPNDDSDVTPRSCEKLESSASSSPQEANVANKGKIVKLVRVQGIEVDMDIPFLWVANNLKNPECYLHICVYVGTRKREPKDGR
What is the function of this protein?
Required for autophagy.  Conjugation to ATG12 is essential for plant nutrient recycling (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNF_SHIFL
Sequence: MCLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CARA_OCEIH
Sequence: MKKRKLILEDGTVFNGTAFGSDAESSGEIVFNTGMTGYQEVITDPSYCGQFVTLTYPLIGNYGINRDDFETVTPFIHGLVVKEYSEFPSNFRNEETLDEFLQAHNIPGIANIDTRKLTRIIRKHGTMRAVMVDEQKNEQHVIEQLRLAEMPRDQVKRTSTIKPYVVPGRGLRVVMVDFGAKHGILRELTRRDCHITVVPHNYSAEAILRLKPDGIMLTNGPGDPKDVPEAIEMIKQLLGQIPIFGICLGHQLLALACGADTEKMKFGHRGANHPVKDLLAGKTYLTSQNHSYAVNVSSLVNTDLELTQIALNDDTVEGIRHTAFPAFSVQYHPEASPGPEDTNFLFDEFLNLIKASKVKQGGEVYA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: TRET_RUBXD
Sequence: MLQRVNPGHKALADYRSIIRRELYGELQELAGRLRGARVLHINATSFGGGVAEILYTLVPLARDAGLEVEWAIMFGAEPFFNVTKRFHNALQGADYELTIEDRAIYEEYNRRTAQALAESGEEWDIVFVHDPQPALVREFSGGLGEGTRWIWRCHIDTSTPNRQVLDYLWPYIADYDAQVYTMREYTPPGVEMPGLTLIPPAIDPLSPKNMALSRDDASYIVSQFGVDVERPFLLQVSRFDPWKDPLGVIDVYRMVKEEVGEVQLVLVGSMAHDDPEGWDYWYKTVNYAGGDPDIFLFSNLTNVGAIEVNAFQSLADVVIQKSIREGFGLVVSEALWKARPVVASRVGGIPMQITAGGGILIDTIPEAAAACAKLLSDPEFAREMGRRGKEHVRANFLTPRLLRDDLRLFAKLLGV
What is the function of this protein?
Synthesizes trehalose from ADP-glucose and glucose.  The reaction is reversible, the equilibrium strongly favors trehalose synthesis.
What are the official names of this protein?
Trehalose synthase, Trehalose glycosyltransferring synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: STTB_ASPTN
Sequence: MSISNMTSTVWPDLQVPAIEHNHLPILTVALLTGIASAVYINVSSVQDPCKVGSIPTVKRPRLLDAYRSGVWWRIFVPRLVPYIEEGYHKYNKNDQPFRIWLGGFQAYAYVLPERYLDKIKNMPESEASFAAMANKYFHTGLPTGEVNNLVLQVASKLVNGNLATIKTLMQGEVQKALAREIGSPRQWTKINAWQVARKTTEAPGLRVVFGEELANDKTFVTGVSEFVSNITVYAFTLRYINLGPLRDFILYLVHWRHRRSLPAVLTPLNNVITERKKVRSNRHISDDEESFDCIQWALDQPVSDDCKTAEAIARRLVVISLGTIDTVAGVLVKQLTHLASHPECHEEIRAEIRECLAEDDNGWTLKSTGRMKKLESFIQESLRMSSGAISLSGMRIVTGSGFRLDDNTVLPRDSFIAIPTRNILYDPEVFPEPEKFDPFRFYKIKEDEKNAGSRSNRRDIRASWLAFGYGRQACPGRFYAINAMKTILGEILLKYDIRLAEKQAPRIDIDLDPMLAPVRSTDLEFRVRA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspterpenacids (PubMed:28604695, PubMed:34085529).  Performs the C22-oxidative modification of the terpene synthase sttA product preaspterpenacid I to produce preaspterpenacid II (PubMed:34085529).  It has still to be determined how preaspterpenacid II is further modified to produce aspterpenacids (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase sttB, Aspterpenacid biosynthesis cluster protein sttB, Ophiobolin family sesterterpenoid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MNME_MYCMS
Sequence: MLINDTVVAPATNISTQAIALIRVSGSEAFLIVNKLIKDKKLEEKRGLFLRKLYFEDELIDEVVLSCFVAPNSFTGENVVEIACHGGILNTNKIINILIQSGARMALRGEFSQRSFLNGKIDLIQAEGINNLIHAKNELALKIGVANMSGSNNKAIIELKDNLLDIISRIQVSIDYPDYDDVEGSSIEDLTNLLEIINDQINKLLMRSKMAFKNSEGIKTAIIGQTNVGKSSILNALINEDKAIVTDIPGTTRDIVEGQINLENVSLNLIDTAGIRKTSDVVENLGILKSKNLINEADLVLFVVNKENINDLDNQEIFELLKNKTYILIVNKAEKLSKTEKQNLEKKYQNIVFTSAINHDIDQLVLRINQMYLNEEINKNDELILIGLNQITLVEQIKNKLSTALSIIKSGMPIDIVNVDLYDAWNLLNELIGVEYEDEIIDNIFRKYCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1971_YERPP
Sequence: MDMTNAQRLILSNQYKMMTMLDPENAERYRRQQTIVERGFGLQMRELDRDFGEMSEDTCRTIINIMEMHHALQVSWGNLKEKQDLDERRISFLGFDAATESRYLSYVRFMVNTEGRYTHFDSGTHGFNSQTPMWDKYQRMLAIWQSCPRQYHLSAVEISQIINA
What are the official names of this protein?
UPF0304 protein YPDSF_1971.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: DAPB_PROMT
Sequence: MSSANQSIPVLVAGAMGRMGSEVVKAINSSKDFQLVGAIDNQKDKEGQDIGSLLGLGELDVFLSSDFEGSLCAASQNVPKDGSNNGAVLVDFTHPKFAYKHTRTSIAYGVHPVIGTTGITADQLDDLSKFADKASLGSAIIPNFSVGMVLLQQAAAAAARFYEFAELTEMHHNKKADAPSGTCIKTAELIEEQRSNFNRSFVEEEESIKGSRGGSRASGLRLHSVRLPGLVAHQQVMFGSNGETYELSHNTIDRSAYMPGVLLVIKKIRSFNKLVYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PSEU2
Sequence: MAEQTASGYIQHHLQNLTFGHLPNGEWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFVLIFRMAAKKATSGQPGALQNFVEVLVEFVDGSVKDSFHGRSAVIAPLALTIFVWVFLMNAVDLVPVDWIPQLAMMISGDSHIPFRAVSTTDPNATLGMALSVFALIIFYSIKVKGIGGFIGELTLHPFGSKNLFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATD_AERPE
Sequence: MEVRRGDGSVFRGVLMPKHETSHPDTVVIKLGNGYNIGVLVGEGDDIVVKGSLRPGTPGALVPLLEEPLQPAEERVYIIGAGGTIASRVDYETGAVKPYLDASELATTIPELQRYASIEAEQLFSILSEDMKPSMWEAIVDRAARVLEAGYDGVVVAHGTDTMAFTASALSFAFHKGLPSPVILTGSQRSSDRPSSDAAFNLTASVLAASRAPFAEVAVVMHGETGDTYALAHRGVRVKKMHSSRRDAFQSVNDKPLARIYPFEGRVEMLRDDYRRRGESGLEVDNGFEERVALVKHFPGLISEVIDALLDRGFKGIVVEGTGFGHVSSDAIKSIERARDQGVPIVITTQTVFGRVNLNVYSTGRKMLAAGAIPAGDMTSEAAYAKLSWILARTRELEVVRKMFQRNLAGEVSERHILRLYRHIGGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: PTH_BIFLS
Sequence: MASDFWLIAGLGNPGKKYEDTRHNMGFMTADVLAERWTVNFADHKGLAMLGKSVMNLDGRTVKFFLAKPLTYMNDSGNAVASISAYYQIEPDHIVVIHDDMDLEFGRIKVKAGGSAGGHNGIKSIDRSLGTPKYARVRMGVGHSKRGANAHDNTVNWVLGGFGPDQRKQLPEFLADGADAAEDIIFHGLAKTQEKFNGR
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNS1_MACFA
Sequence: MASKRRNMSCSERHQKLVDENYCKKLHVQALKNINSQIRNRMVQNENDNRVERKQFLRLLQNEQFELDMEEAIQKAEENKRLKELLLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNKVKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDRLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVQQELYQEEQAEIYKRKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADKQQELEEWQLQQRRQGFINAIIEEERLKLLKEHATNLLGYLPKGVFKKEDDIDLLGEEFRKVYQQRSEICEDK
What is the function of this protein?
May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity).  Required for sperm flagella assembly (By similarity).  May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC).  ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity).
What are the official names of this protein?
Meiosis-specific nuclear structural protein 1.
What is the protein family that this protein belongs to?
Belongs to the MNS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: RL9_HAEIG
Sequence: MQVILLDKIVHLGQVGDQVNVKSGFARNFLIPQGKAVMATKANIEHFEARRAELEATAAANLAAAQARAAEVTALGSVTIASKAGDEGRLFGAITTRDVAEAVTAAGVKIAKSEVRLPNGPIRTLGDHDVRFQLHGEVFATLDVIVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.