PharMolix/UniProtQA huggingface dataset:
Protein: PMM_SPIOL
Sequence: MAAKPAIIALFDVDGTLTAPRKEVTPEMLKFMKELRKVVPVGVVGGSDLTKISEQLGKTVINDYDYVFAENGLVAYKDGAEVAIMSLKKLLGEEKLKEFINFTLKYIAELDIPIKRGTFIEFRNGMINVSPIGRNCSQEERDEFEKYDKIQKVRSTMVSVLREKFGHFNLTFSIGGQISFDVFPRGWDKTYSLRYLEDFNEIHFFGDKTFEGGNDYEIFASERTVGHTVTSPEDTMKQCTEIFLTKKE
What is the function of this protein?
Catalyzes the interconversion of mannose-6-phosphate to mannose-1-phosphate, the precursor for the synthesis of GDP-mannose (PubMed:9003801).  GDP-mannose is an essential sugar nucleotide for the synthesis of D-mannose-containing cell wall polysaccharides (galactomannans and glucomannans), glycolipids, glycoproteins and the antioxidant L-ascorbate (Probable).
What are the official names of this protein?
Phosphomannomutase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPN2_BOVIN
Sequence: MALPGSSTVFLLALTIIASTQALTPTHYLTKHDVERLKASLDRPFTSLESAFYSIVGLSSLGAQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQALSGCEISISNETKDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASQEALGALTARLSKEETVLATVQALQTASYLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAALSENRYHVPVVVVPEGSPSYTQEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTLIGDVFELNFMNVKFSSGYYDFSVKVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDSKNVYKFELDTSERKLEFDSASGTYTLYLIIGDATLKNPILWNVADVVIRFPEDDVPSTVLSKNIFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIVFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAIKRTAH
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit, Ribophorin II, RPN-II, Ribophorin-2.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: RLPA_ECO57
Sequence: MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEISGADPRFEPLNATANQDYQRDGKSYKIVQDPSRFIQAGLAAIYDAEPGSNLTASGEAFDPTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSNNTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILPVSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPAMVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGPFANKAEASTLQQRLQTEAQLQSFITTAQ
What is the function of this protein?
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
What are the official names of this protein?
Endolytic peptidoglycan transglycosylase RlpA, Rare lipoprotein A.
What is the protein family that this protein belongs to?
Belongs to the RlpA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL34_RALSO
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRGGRAVLNARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NAM1_HORVV
Sequence: MGSPDSSSGSAQKPPRHQHQHQPPPPRRQGSAPELPPGFRFHPTDEELVVHYLKKKAAKAPLPVTIIAEVDLYKFDPWELPEKATFGEHEWYFFSPRDRKYANGARPNRAATSGYWKATGTDKPILASATGCGREKVGVKKALVFYRGKPPRGLKTNWIMHEYRLTGASAGSTTTSRPPPVTGGSRAPASLRLDDWVLCRIYKKTSKAAAAVGDEQRSMECEDSVEDAVTAYPPYATAGMAGAGAHGSNYVQLLHHHDSHEDNFQLDGLLTEHDVGLSAGAASLGHLAAAARATKQFLAPSSSTPFNWLEASTGGSILPQARNFPGFNRSRNVGSMSLSSTADDMAGAVDVSDGGNAVNAMYLPVQDGTYHQHVILGAPLAPEAIAGAATSGFQHHVQISGVNWNP
What is the function of this protein?
Transcription factor of the NAC family associated with the grain protein content (GPC).  Accelerates senescence and increases nutrient remobilization from leaves to developing grains.  Sequences of 11 European varieties of H. vulgare tested belongs to the same haplotype while the sequence found in H. spontaneum, an ancestor of the cultivated H. vulgare which has a higher GPC, belongs to an other haplotype.
What are the official names of this protein?
NAC transcription factor NAM-1, HvNAM-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACO1_SCHPO
Sequence: MTAPSATAFSSATTQPTTEGNASMRKRTIPVVPSVPERKWDPKAPKHIQEQPWTMQNWWRHLNWLHCMLIFGLPMIAIYGVFTTPLQTKTLIFAIIYYAYSGLGITAGYHRLWSHRAYKAKKPLEYFLAAGGAAAFEGSIRWWSRDHRAHHRYTDTDKDPYNVKKGFWYAHVGWMIILQNPRRIGRSDVSDLNSDPFVMFNHRHFLPIASFMAFIFPSLFCGLLWGDYRGGYFYAGVCRLVFVHHATFCVNSLAHLIGSQPFDDTNSARNHFITALVTLGEGNHNYHHAFPNDYRNGLRWYEYDPTKIFIYIASLFGLAYNLNTFPDNEIQKGIVQQKQKVLDRWRAKLNWGIPLEQLPVMEFEDFLEQSKTRPLVLINGVVHDMTGFEHPGGQGLLRSAFGKDATAAFNGGVYDHTNGAHNLLSTYRVAVVRGGMEVEVWKSGAGAQLPMKDTQGQKIVRVGEQITRIQPPIEAAAAN
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides.
What are the official names of this protein?
Probable acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: FABH_TRIV2
Sequence: MQNLGIAITGSGSAAPETSLHNEELSQLVETSDEWISTRTGIRQRRLALPTESLSSLAAAASRQAIASAGITASDIDLILLATSTPDDLFGTATKIQAELGATKAVAFDLTAACSGFVFGLVTAAQFIRTGVYQNVLLIGADILSRWVDWQDRRTCVLFGDGAGAIVLQSNQSDRLLGFALKSDGTQNHYLNLAYQGTAQEILPNIKITQGTYQPVTMNGKEVYRFAAQKVPEIIDKALFEANITVDQIDWLLLHQANQRILDTVAQRLNIPAHKVISNLANYGNTSAASIPLALDEAVREGKIKPNDIIATSGFGAGLTWGAAIFQWGR
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BBLC1_TOBAC
Sequence: MFPLIILISFSFTFLSASATSGAGEGVANLSTCLINHNVHNFSMYPTSRNYFNLLDFSLQNLRFAASNMPKPTVIILPNSKEELVSTILCCRQTSYEIRVRCGGHSYEGTSSVSFDGSPFVIIDLMKLDDVSVDLDSETAWAQGGATIGQIYYAIAKASDVHAFSAGSGPTVGSGGHISGGGFGLLSRKFGVAADSVVDALLIDADGRLLDRKAMGEDVFWAIRGGGGGNWGIIYAWKIRLVKVPKIVTTFKISKPGSKQYVAPLLYKWQIVAPNLADDFTLGVQMIPIDLPADMKYGNPTPIEICPQFNGLYLGPKTEAVSILNEAFPELNVKNDDAKEMTWIESALFFSDLDNIFGNSSDDISHLKERYLGVKICFKGKSDYVKTPFSMDGIMTALVEHEKNPNAFLVFDPYGGAMDKISAQAIAFPHRKGNLFAIQYYAQWNEEDDAKSNEHIEWIRGFYNKMAPFVSSSPRGAYVNYLDMDLGMNMDDDYLLRNASSRYSSSVDAVERARAWGEKYFLNNYDRLVKAKTKIDPLNVFRHEQSIPPTLGSTQEHNYSSE
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:21343426).  Catalyzes a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of alkaloids (PubMed:21343426).
What are the official names of this protein?
Berberine bridge enzyme-like C-1, NtBBLc.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NOSIP_DROME
Sequence: MTRHARNCTAGAVYTYNEKKRDAAESGYGTNAQRLGKDSVKSFDCCSLTLQPCRRPVITKDGYLFDKEAILQYIVTKKNEYSRRLKEYERLRRAEEDKLSQEANSKQQARMERFVNAEKPAMTPAHSSAAASEKPSTSSAAAAASSESSSASSISNMTNGHEKKLPSFWLPSECPNAGLAKAQKPDATIYCPVSQKPLRVKDLIDVKFTLLKDGDTKRSLIAKEARYMCPITHDVLSNAVPCAVLRPTGDVVTMECVERLIRKDMIHPLTDRKLKEKDIIPLQRGGTGYATTNDHLQAKEKRPMLQA
What is the function of this protein?
Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
What are the official names of this protein?
Nitric oxide synthase-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the NOSIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GRP3_PINMA
Sequence: MRYAVLLAVVLLLGAFTAEAFSPPPFHICKWKLWKCLKWCAPWDWKCRRKCFWKYWWCLKKFGGHYGGYGYGDDGYGGGGYGGGGYGGGYGGGYGGGYGGGYGDVGYGGGYSGGYSGGYSGGYGSYGHRRKY
What are the official names of this protein?
Glycine-rich protein 3, Lysine-rich matrix protein 7, KRMP7.
What are the subcellular locations of this protein?
Secreted.
Protein: PRX5_PENCI
Sequence: MSLKAGDSFPEGVTFSYIPWAEDASEITSCGIPINYNASKEFANKKVVLFALPGAFTPVCSANHVPEYIQKLPELRAKGVDQVAVLAYNDAYVMSAWGKANGVTGDDILFLSDPEAKFSKSIGWADEEGRTYRYVLVIDNGKIIYAAKEAAKNSLELSRADHVLKQL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin Pen c 3, Prx, Peroxisomal membrane protein, Thioredoxin peroxidase, TPx, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
Protein: SDHD_BACC3
Sequence: MKEIEKLKEEYPLLNKLIETEEVLWVNPNMEKYETAIKDSPLSEENVKDAKERLKRFASYIAKVFPETKETKGIIESPLLKIPSMKQALEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQHGMLTEEDDYSILDSDTCREFFAKYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGDYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVRVCKEDAYLQKQQLMEKMQKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: SYS_WOLPM
Sequence: MHDIEYIRKNPEGFEKAMKSRGIRESTAEEILEIDHEKRSLTTKLQDLNRQRNEITEEIKKLKMSKSPCEEQIELSKSITNEIEAISLKEQAEKDKLVNVLSNLPNIPAQDVPIGADENSNLEVRRYGGKRQFDFVPESHYELGEKLGLMDFEQAARISGSRFTILKGQLAKLGRALINCMLEMHVNEFGYTEVYHPALVKNEAMYNVGQLPKFSDDSYLTTDELRLIPTSEVFLTNLVADKIMEEKELPIRFTAYSECFRKEAGSAGRDTRGMIRQHQFGKVELVSITTEDQSNDELERMTSVAEEILKKLELPYRVMLLCSGDMGFAAQRTYDIEVWLPGQNKYREISSCSNCGAFQARRMNTKYSSETDKKMKKYIHTLNGSALAIGRTIIAIMENYQNSDGSIAIPNVLQKYMSNDTVISK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4LA_SINFN
Sequence: MERFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALAMAMDIADAQAVAALFETAERHFGGVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMATNLRGTLLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQYGHAQIRCNAVAPGLIMTERLLAKLDKCMQRHLSRHQLLPRVGHPEDVAALVAFLLSDDASFITGQVVCIDGGMLAHMPTYADGGNSCAGRTAGDTAETARC
What are the official names of this protein?
Uncharacterized short-chain type dehydrogenase/reductase y4lA.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: YACG_SHESH
Sequence: MTTTVKCPTCQKEVIWNSESKFKPFCSDRCKLIDLGDWASEKHAIPVKSEFDPETLDGLGYDEADFFKDQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: SYFA_PSEE4
Sequence: MENLDALVAQALEAVQRAEDITTLEQIRVQFLGKKGELTQVMKTLGNLPAEERPKVGALINDAKERVTDVLNARKAGFEEAELNARLAAECIDVTLPGRGQTTGGLHPITRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESSQPPIRIVCPGRVYRCDSDITHSPMFHQVEGLLIDRGINFADLKGTIEEFLRVFFEKELAVRFRPSFFPFTEPSAEVDIQCVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLAQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX6_SCHPO
Sequence: MENRICTLAKPLPKLDESKQAWVSYLWLKKALPGFEEHSAYVYMTTNPTIAGRIFLPINNEDLEDGTVEISGYDNLLADALYISTIAPVKLDFVQLIVIDDNSQDQDAIIERIKGRNAILMESDFINQNILVQVCQPVRHGVVDSETKFVIERKDSFTFLASNEKNISSFKRGKTETDAELVIRPSKVHTEIQWCLQNCSLIHVPFELLFNVGKKNGCPISLRLSDGKNVYGIASIKSDTEHDSVQLSPSLHYFDEFNESVISEEGTEAFLVARGPSVGIASRISLRTIPTQSCFSEKLLKAANLCVVQQVKQKVFLQSKQIFCVPINSLMANSDSVDILELTRNTDAYIWYSVEEIDPLNTYNIYYTNEDTSIVLDTQLSHRLLPSLRKPLLNFVKVHPPSQKLLRFCRAFFDPQQVPGFNPFFLLHGNPFTGKTKAVEEVASLFSAPVFTISSYEFADATADHLEAKLDMFVQNVVKSPCAIIFVKDLDVLSISSDEGNIVPGSKSIQILLSKIDLVKSPQGRYIVIGTCHSIEKIPYEILSESFFELKFSELEMDERLELLKIYANNVIIDKRISLKDVALKTNSMSFGELECLPDHMTKAAVDRIKRTGYDNDSIILSGPIITEQDVDVSINRIRKEKSNTIFTVPKVNWDDIGGLEEAKTVLRDTLQLPLQFPELFSQGLKPRSGVLLYGPPGTGKTLLAKAVATELSLEFVSIKGPELLNMYVGESEANVRNVFEKARNSSPCVIFFDELDSIAPHRGNSSDSGNVMDRVVSQLLAELDSISKDNNKYVFVIGATNRPDLLDPSLLRPGRFDKLVYLGINKSEESKASMLRALTKTFKLDETIDLNEIAKNCHPNFTGADMYALCSDAVLSAIKRKTNEIDLLIQASGTDLSTEEFFKRNENQDSLELRITKEDFLTSLKKLRPSISEQELHRYEMVRHQFS
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase pex6, Peroxin-6, Peroxisome biosynthesis protein pex6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEPA_TOLAT
Sequence: MKNIRNFSIIAHIDHGKSTLSDRLIQMCGGLSEREMQAQVLDSMDLERERGITIKAQSVTLDYKANDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALEMNLEVVPVLNKIDLPQAEPERVAEEIEDIVGIDAMDAVRCSAKTGLGVDDVLEEIVKRIPAPEGDPDAPLQALIIDSWFDDYLGVVSLVRIKNGSLKKNDKIKVMSTGQTWGVDRLGISTPKQKDTLALNCGEVGWVVCGIKDIHGAPVGDTLTLAKNGAESALPGFKKVKPQVYAGLFPISSDDYESFRDALEKLSLNDASLFYEPENSTALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEIVQTDGTIIHIDSPSNLPAINNIQELREPIAECNILVPQDYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYGFKRFDAADMVRLDIMINGERVDALAIITHKDNAPFRGRQLVEKMRELIPRQMFDIAIQAAIGNHIIARSTVKAMRKDVLAKCYGGDVSRKKKLLNKQKEGKKRMKSVGRVDVPQEAFLAILHVGKDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PPK2_KARBO
Sequence: SPPFAPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-2, PK-2, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_OCEIH
Sequence: MPYITDVYAREVLDSRGNPTIEVEIFTESGAFGSAIVPSGASTGEYEAVELRDGDKDRYLGKGVQKAVENVNDLIAPELIGIDVTRQNIIDALMIDLDGTENKGKLGANAILGVSMAAAHAAANYLEVPLYNYLGGFNAKTLPTPMMNILNGGEHADNNVDIQEFMIMPVGAPTFKEALRTGAEIFHALKKVLTSKGYNTAVGDEGGFAPNLGSNEEALQTIVEAIEAAGYKPGEEVKLAMDVAASEIYSDGKYNLKGEGVVRSSEEMVDWYEEMISKYPIISIEDGLDENDWDGFKILTDRLGDKVQLVGDDLFVTNTNKLSKGIDQGIGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVISHRSGETEDVTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELAGMGEYGGLASFYNLANK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PYRB_DINSH
Sequence: MTLRARHLLGIEHLAPDEIVTLLDLADRYADLNRRPDKHGDALDGLTQINMFFENSTRTQASFEIAGKRLGADVMNMEVRASSIKKGETLIDTAMTLNAMHPDLLVVRHPHSGAVNLLAEKVNCAVLNAGDGRHEHPTQALLDALTIRRAKGKLHRLNVAICGDIAHSRVARSNILLLGKMENRIRLVGPRTLMPAEIAELGVEVYEDMKAGLDGVDVVMMLRLQKERMDGGFIPSEREYYHRYGLDAEKLAYAKPDAIVMHPGPMNRGVEIDGTLADDINRSVIQEQVEMGVAVRMAAMDLLARNLRAAREGVRA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CTU2_DROSI
Sequence: MCSIGEDDFGDDGAAHAMAVESLPLGIVLSPGNCSKCDVNSDELYKLNFRTAECRECFLAYARHKFRAALGAAKILPRNAEVLLVLDGSAESLVLLDMLHFAQTQNTFKRLHCNARVVYVEEQQVQGRDPVHLEALQNLSTQYAPFDFYVIELGALPSSMQRIKDYSPSLNANNELIHKLQKLRSLTARQDYLQQQRKNLICSVAQCLRCTHVFESNISVDLATQLLTAIALGRGGSAALDVALLDDRLSGDVKLLRPLKDLNEQEIQFYIHAQRLKPLFQKGSRYGREHGQTASLQNLTSAFVANLQQNYASTVSTVFRTGDKIAANSNPEQSSCVHCRSTLDTELSDTLLAIEYSRSVSEAGVSLYKSGQDLEDLAKKRLENKDGLCHACRAIQAELDSGNLL
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG17_RAT
Sequence: MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLAFELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGNALAPAGPELPSQSSRADSNSVGGPVPSSSGILEQGLSPGDSSPPKPKDSVSAAAPVAGRNSNQITTVPNQAQTGGNSHQLSVGTAHSAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTGTSPKPSTRSPSPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPNHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPPAKQNSSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPNPPGTHMGDGGLTPSVPTASRIVTDTNSRVSESLRNIFPEIHSDLASKEVPGHILLDIDNDTESTAL
What is the function of this protein?
Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells.  Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state.  The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere (By similarity).  Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments.  Acts as a GTPase activator in vitro for RAC1.
What are the official names of this protein?
Rho GTPase-activating protein 17, Neuron-associated developmentally-regulated protein, Nadrin, Rho-type GTPase-activating protein 17.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Cell junction, tight junction. Note=Associates with membranes and concentrates at sites of cell-cell contact.
Protein: CBPM_ECO55
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: AMIN_BACSU
Sequence: MLDVHKDIKKIFHEEQVLAEAAARYGFSKDQVRFLADAENYVYECMKDNQPYILKITHTIRRSSDYMMGEMEWLRHLAIGGISVAKPLPSLNGKDVEAVPDGNGGSFLLRVYEKAPGQKVDESDWNETLFYELGRYTGSMHSLTKSYKLSNPAFKRQEWDEEEQLKLRKYVPEDQIKVFQQADSLMNELRRLPKSQDNYGLVHADLHHGNFNWDHGKITAFDFDDIGYNWFVNDISILLYNVLWYPVVPYDDKAAFTEEFMTHFMKGYWEENELDPAWLMIIPDFLRLRHMLIYGLLHQMFDLNTIGEEEKEMLAGFRRDIENGTPITAFDFSALV
What is the function of this protein?
Phosphorylates the antibiotic amicoumacin A (Ami), leading to its inactivation.  Mediates natural B. subtilis resistance to the drug.
What are the official names of this protein?
Amicoumacin kinase, Kinase AmiN.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: CTXN2_DANRE
Sequence: MCSVHYNHSLAAMSGSDIMAYSLSLEQKTAFAFVGMLLVFLGLLIVRCFRILLDPYSSMPSSSWGDGLEGLEKGTFEYALT
What are the official names of this protein?
Cortexin-2.
What is the protein family that this protein belongs to?
Belongs to the cortexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.