PharMolix/UniProtQA huggingface dataset:
Protein: GCA_DICDI
Sequence: MMFGNLPDVRKPKEGYKKYLEYFDLRFPRIQEEKHFQSYYYYTYLKQIRISIIFLTSVLFIGTMTAYISPLDISYLPYYDSKNIYYFNYVQPNVTTTSSSTTTTSSTTNSIDSTVENNNFTEADGHLTNYYFPYLANKARDTFILRMITIGLLLFYFIFTFTAKFKRLWKLFTTITLFLVSCIVLIFESDIRTIPGRMVLLFIIIAISSGMTFLPSMLASGGLCLFFFFYFMFYSQIAGKQMVLLSLVLLISWIILMIISRFKEQLFRDKFRTLENLKIQTIRSEKIINQMLPTVVVQRLRLQSSKDQSLETTLENDKELSIKKDEESNLTGKKQSKVVVSPPPPPTAAAPQQQDNEISTPQNSRKIVDPQSPSSLMPGQYSVTDLIVDSYDPVTVLFCEIVNFNALVEKMSSTQVINLLNEVYNSFDRLTDVYGVTKVEHIGNVYMVVGGCPELCPDHAQRVAHMSLGMLSVIRRFGIVQVRIGMHTGPVVGGIIGKKKLSWHLFGDTINTSSRMASHSSIGRIQVSHPVQQLLRPYFLFEDRGKIQVKGKGLMRTFYLVKTKQLDKRYTSIFSSLHREKPYIPPVDISEVSFENQNNTIGKGDDIASGSATGPTHPNIPNSMLSAIPSRVSIEMNPLGGSGSIQKRERKGSIFANVMPPKVLNFLQTGSLTSPQQQPLPQQSNSEETISNSPRLSSTPQSTSTLQHSSSTGALGSLINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLPVSLISPISQNTTPTGSLSLPVTEKKKQTVQFGSISRSSSISKGTVGRSPSPALFDGGIEMDDNGGGAGDDFNTMEPNLDLGKGIHGSNVISTNNSKLNKLEKDLTKHYTLDKFKLSFISRGNLVEKEYRNEYILKNWNRILASMLMIVALFGLSGLVDYFFLKLSSISSIVKVEPMPSSSSSSLSSSSSNSMTSSEEKFITLHTIRSEENLIYDIITGVRYGFVFFCLIVIYVVSKFKTFSIRKWIQEVVMVFFIVLAAVLIVLTSVPPLNKIPLDSVILSIEIMFITICYNFSGIKFWYSNIVCAFCIIFIEISKTWKQAYHSRDIYLSHNYYLITAVLINIITSYFEELFNRLNWVHGRLLDKDQRETESLVAEILPADIVKSMKSGRQLIVDEFKNVTIFLSDIVGFTEMAARMSPRQLVETLNQIYSTFDEIAQEFGVLKIATIGDAYFCVSGCPDKDQTDHAFRVANMAIKMLESIKSIRTVDNIPIRMRIGIHTGPVIAGVVGIKMIHYQLWGESVQITQQMESTSRADMIHVSEDTFNILKSKYLFEERPDGIIKKRKIKTYFLLRALTENDPQPEVKTRSVSVSKSNFGGSLQYNQITPTLNLPVSQLIIKDQNEIKNQNDHDNDDENGNENGNESSSSNINEEEEDDDNSNNNNNNEDDESSYEDDQEMNQYLNNSENNKNNNNNSNQINEEDGNWAKNYDGSSESS
What is the function of this protein?
Synthesizes cyclic GMP (cGMP) from GTP, after activation by heterotrimeric or monomeric G proteins (PubMed:11237875, PubMed:11522784, PubMed:11777934).  Involved in chemotaxis (PubMed:11777934).
What are the official names of this protein?
Guanylyl cyclase, membrane, DdGCA, GCA, Guanylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECY_SYNE7
Sequence: MVVSRGKTPNAQETFLQMAQASGLRGRILITVGLLILCRLGIFIPVPGIDRVAFSNDLQGNANLGGVIGFLDIFSGGGLSALGVFALGILPYINASIILQLLTAAVPALEDLQKNEGEAGRRKIAQLTRYVSLGWALLQSIVIAVWVTRYAVTPGPLFTIQTALALVAGSMFVMWISELITERGIGNGASLLIFLNIVATLPRSLQQTLELAQSGDRSTVGGIVILLIVFLATIVGIVFVQEGTRRIPVVSARRQVGNRVYSERSSYLPLRLNQGGVMPIIFASAILVLPFSLANFTSNEVVLRIANYLSPNGPTPWIYALFYLVLIVAFSYFYSSLILNPVDLAQNLKKMGSSIPGVRPGRATSQYVQGVLNRLTILGAVFLGLVAIIPTAVEGATRIRTFQGFGATSLLILVGVAIDTAKQVQTYVISQRYEGMVKD
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FLIW2_HELPJ
Sequence: MIFDVKAPILGFETIHKMHLQKIDEIFLRLNSAEDNSVVSFTLVNPFALRKYEFEVPTPLKILLELEGAKSVLVANIMVVQTPIELSTVNYLAPLIFNLDKQLMGQVVLDSKKYPHYHLRENILSHTHE
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW 2.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDX5_PAPHA
Sequence: MGLAGVCVLRRSAGYILGGAAGQSVAATAAARRRSEGGWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVLACLSVNDAFVTGEWGRAHKVEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPSIISQL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin-5, mitochondrial, Peroxiredoxin V, Prx-V, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin 5.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic+peroxisomal]: Cytoplasm. Peroxisome matrix.
Protein: AACA_STAWA
Sequence: MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD
What is the function of this protein?
Involved in resistance to gentamicin, tobramycin, and kanamycin.  Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region.  The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides.
What are the official names of this protein?
Bifunctional AAC/APH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the aminoglycoside phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_ACAM1
Sequence: MTQSTVSSTIVEPYAEALMSVAQSNNLTNQIGEDVSFVLSLLQTSDDLKDFLVNPLTPADAQKAVLRQLAESRVQKQFFNFLLLLIDRRRIIFLEGICKYYQALLRKLNNTVLAEVTSTVELTDEQRHAITDKVKHMSQAAQVDLETSIDPDLIGGVIIKIGSQVLDASIRGQLRRMNSSITSLS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: DXR_ANASK
Sequence: MKRVAILGSTGSIGVQALDVVGRFPDRFEVVGLAAGRNAPRLLEQIRRFRPRVVSVCDEAAARAVRAEAPPGTEVLSGDAGAVAVASHPDAAFVLAAISGGAGLRSTAAAIEAGKPVGLANKESMVLAGELLMARAAAKGVPILPVDSEHSAIHQSLVGHNRGEVRRLILTASGGPLRCTPEAELATVTPERALKHPNWSMGDKITIDSATLMNKGLEVIEARWLFGVEQQRIDIVVHPESVVHSMVEYVDGSIVAQLGISDMRGPISYAMGHPERMPLDLPPLDLGRLGKLTFEPPDPARFPAYTLAYRALELGGTAPAVLSGADEAAVAAFLARRCSFTGIAEVCADVLEAHVVEPVRSVEQALAASEHGRREAEKRVGARAHAPAGR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RUVB_ECOBW
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CYOE_ERWT9
Sequence: MIKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYSLFLATLVGVSLVVASGCVYNNFIDRDIDKKMERTKNRVLVKGLISPKLSLVYATVLGIAGFALLYFGANPLAMWLAVMGFVVYVGVYSLYMKRNSVYGTLIGSLSGAAPPVIGYCAVSGQFDAGALILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITVYIIAFMVATLMLTLVGYAGYKYLVVASAVSVWWLGMALSGYKTQNDRVWARKLFVFSIVAITALSVMMSIDFMTPASKDLLTYIG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_STRPZ
Sequence: MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLVVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLKGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DAPF_SYNP2
Sequence: MVLEFTKYQGLGNDFILLDNRQQTTPLVTPEQAIQLCDRHFGIGADGVIFALPGQAGADYTMRIFNSDGSEPEMCGNGIRCLARFIDHLEGGNAPGKTYSIHTLAGMIRPRLETDALVRVDMGEPILTATDIPTTLKDSNGQAVNQPLEVAGKTWMVTCVSMGNPHCITFVEDVAAIALEVIGKDFEHHPAFPQRINTEFIEVVRPDYIKMRVWERGAGITLACGTGACASVVAGVLTGHCDRLCTVELPGGCLQIEWSAADNHIYMTGPAAISFQGQVTL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF1_PONAB
Sequence: MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFGEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.  Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCH8_ARATH
Sequence: MDSTATVASDRLSQLNSFEETMTGVKGLVDSGIKEVPAMFREPPAILASRKPPLALQFTIPTIDLNGGVVYYKNQDSVTRRSMVEKIGDAAEKWGFFQVVNHGIPLDVLEKVKEGIRAFHEQDAELKKRFYSRDHTRKMVYYSNLDLFTAMKASWRDTMCAYMAPDPPTSEDLPEVCGEIMMEYAKEIMNLGELIFELLSEALGLNNSNHLKDMDCSKSLVLFGQYYPPCPQPDHTLGLSKHTDFSFLTIVLQGNLGGLQVLHDKQYWIDIPPVPGALVVNLGDLLQLISNGKFISVEHRVIANRAAEPRISVPCFFSTVMRESHRVYGPIKELLSEQNPPKYRDTTISEFASMYASKEINTSALLRLEI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 8.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PYRF_THEVO
Sequence: MDKRIIVALDVKEKKKAIDIAESLSDIVFAFKINWPLVLYSSPEVIGEISQYGKVICDFKVADIPYTNSLITERVRDLGAWGIISHSFLGEESLKSVVNAAKGMHVFSVVAMSHPGSDMINSNAMQLMKLSIECGVYGFVAPANKIDDLRMIRSATDRVIISPGIGAQGGDPYTAVLNGSDYLIVGRSVYESDKPELEVSKLQQTAERAIEDRERLKNS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CARB_BACHK
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQELNEPTPPSEIIHNLDEAYGFVKEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQTAKEMGFSDHYIAAAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFESATPYYYSTYADENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFEDQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: GLGB_METFK
Sequence: MLTKSKQDPHLNHILNARHHDPFSYLGLHQDGTQYILRLFQPFAARAWLQTASGWVPLQRSHEAGLFEWKGNTPPPVPCRIRLEENGHSWETYDAYTFWTTLSPEELYLFGEGRLKQAYRTFGAHLCEQQGVAGVRFVVWAPNAERVSVIGNFNHWDGRMHQMRVHGSSGVWEIFIPGLTSSDLYKFEIRNRQTGQILVKTDPYGFSFEQRPGTAARVTAHGHYAWQDAEWLEDRARADWLHAPFNCYEVHLGSWRRDAHGEFLGYRELAHQLVPYMQEMGYTHIELLPVSEHPLNESWGYQTTGYFAPTNRFGSPDDLRYFVDQCHQAGIGVILDWVPGHFPKDDWALARFDGSALFEHEDPRLGEHQDWGTYIFNYGRNEVRNFLLASAHYWLEEFHMDGLRVDAVASMLYLDYSRKEGEWLPNRHGGRENLEAIDFLKQLNVMVHEDFPGALTIAEESTSWPMVSRPVYLGGLGFSMKWNMGWMNDTLSYMQHDPIHRRFHHDKLTFGQIYAYSENFVLPFSHDEVVHGKRSLLDKMPGDTWQKFANLRLLATYQMTASGKKLNFMGNELAQGREWNVNSSLDWHLLDLHWHQGIQRLHRDLSHLYRQVPALHELDFDAHGFEWIDCSDSDQSIINYLRRARDGSFVLVLLNFTPVLRSGYRVGTPLAGHYREIFNSDAGYYGGSNQGNGNGLQTEAYPWMGHSHSLVVTIPPLGGVIIQPG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: ST65G_MOUSE
Sequence: MLRYWGEIPIPSGQTNRSSFDLLPREFRLVEVHDPPLHQPSANKPKPPTMLDIPSEPCSLTIHTIQLIQHNRRLRSLIATAQTQSQQQTEGVKAEESEPLPSCPGSPPLPDDLQPLDCKNPNAPFQIRHSDPESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHTGFECANESVLETLTDVAHEYCLKFTKLLRFAVDREALLGQTPFPDVMEQVFHEVGIGSVLSLQKFWQHRIKDYHTYMLQISKQLSEEYERIVNPEKATEDTKPVKIKEEPVSDITFPVSEELEADLASGDQSLPIGVLGAQSERFPSNLEVEASPQAPSAEVNASPLWNLAHVKMEPQESEEGNVSAHGVLGSDVFEEPMSGMSEAGLPQSPDDSDSSYGSHSTDSLMGSSPVFNQRCRKRMRKI
What are the official names of this protein?
STAGA complex 65 subunit gamma, SPTF-associated factor 65 gamma, STAF65gamma, Suppressor of Ty 7-like.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAD26_SCHPO
Sequence: MMADESFDLESLGSDEIFEGVNLDELEQQAQTQVQAQSSQVVVPSEKQKQNLNLPNSYTNSSQKVRESTVNSQASLSSNDLRTELLIKSGENAILRANLLKQSEANNAALESLNNSIKQKQDEYQRKLEELKKEIEYAKTKSLFHEREAQDAIETMKKMKRDVKNSPIMKKSHEEDGDNKLLSSSDQLAKSTKHAAKNSPSKKKRKTSVATAEDASTDSVSSSIAISDASLSLSLMKDLLSLQKREDLYFSSRTLAYVFGGCMHSLETIEGEEEGECLFNNLKALIYSPDLSMDSSNYVQSVVQTSSSILNYSMKKLLYNASFAITSLFNALLILDPKSSTFIFQENVVSLISGFLLKEYEKSNFLDSKFYVLIDFLYLYLSIARESADDFANITKAVDPSLFESCIRVQNAPSLIKCGVCLIISSTTPSFCASVNLLNADDKSQESLMQLFTTMAHILVVTTRERINFPELNEWITLHRFVISFFTVFIQMSGNIGKEILKVCNPLIVCIGLAITWYHQQLLSSMYPQNECVEILVSLVRLLYILSSEDLSSKFMLAENALQPRFVYAIACCAFGDTEQKAFGNLGEEMYFLTTELLEVCVSPEELEQLYTNF
What is the function of this protein?
Involved in cell cycle arrest when DNA synthesis is inhibited by hydroxyurea, and in mitosis arrest after treatment with DNA-damaging agents.  This protein is S phase-specific.
What are the official names of this protein?
DNA repair protein rad26.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_AQUPY
Sequence: MSATETKYVPRLYKKYKEEVVPKLIQKFQYKNPMQVPRLVKIVVNMGVGEAVQDIKQLERAVEDLRAITGQQPMITRARKSKAGFKLRKGMPIGCKVTLRNHTMWDFLDKVISVALPRVKDFKGLNPRSFDGRGNYAFGIAEQIVFPEIDYDKVDRIRGMDIIINTTAVSDQESLLATLTLGLPIRAM
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYL_LACDA
Sequence: MYNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMARMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDREIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVIDGKTERGGYPVYRRKMRQWMLKITAYADRLLDDLDDLDWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSFAVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKTGVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVMAVPAHDERDYAFATKFDLPIKEVVEGGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRKGKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYARFWHKVLYDLGVVPTKEPFQKLYNQGLILKNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDRVWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNACQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVFGHDESVQFAAWPTYDASKLVESTVEMAVTVNGKKRGNFQIAKDASREEAQAAATALTHVKEFLEGKEIKKVIVVPNKIVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANGL3_HUMAN
Sequence: MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE
What is the function of this protein?
Involved in angiogenesis.  Binds to endothelial cells via integrin alpha-V/beta-3 (ITGAV:ITGB3), activates FAK, MAPK and Akt signaling pathways and induces cell adhesion and cell migration (PubMed:11877390).  Secreted from podocytes, may modulate properties of glomerular endothelial cells involving integrin alpha-V/beta-3 and Akt signaling (PubMed:18535744).  May increase the motility of podocytes.  May induce actin filament rearrangements in podocytes implicating integrin alpha-V/beta-3 and Rac1 activation.  Binds to hematopoietic stem cells (HSC) and is involved in the regulation of HSC activity probably implicating down-regulation of IKZF1/IKAROS (By similarity).
What are the official names of this protein?
Angiopoietin-related protein 3, Angiopoietin-5, ANG-5, Angiopoietin-like protein 3.
What are the subcellular locations of this protein?
Secreted. Cell projection, lamellipodium. Note=Colocalized with HSPG2 and activated ITGB3 on podocytes.
Protein: ISCR_ECOSM
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: TAFA3_MOUSE
Sequence: MERPTSNWSAGSWVLALCLAWLWTCPASASLQPPTSAVLVKQGTCEVIAAHRCCNRNRIEERSQTVKCSCLSGQVAGTTRAKPSCVDASIVLQKWWCQMEPCLLGEECKVLPDLSGWSCSSGHKVKTTKVTR
What is the function of this protein?
Plays a role in the regulation of microglia polarization.
What are the official names of this protein?
Chemokine-like protein TAFA-3.
What is the protein family that this protein belongs to?
Belongs to the TAFA family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBX2A_HUMAN
Sequence: MKDVDNLKSIKEEWVCETGSDNQPLGNNQQSNCEYFVDSLFEEAQKVSSKCVSPAEQKKQVDVNIKLWKNGFTVNDDFRSYSDGASQQFLNSIKKGELPSELQGIFDKEEVDVKVEDKKNEICLSTKPVFQPFSGQGHRLGSATPKIVSKAKNIEVENKNNLSAVPLNNLEPITNIQIWLANGKRIVQKFNITHRVSHIKDFIEKYQGSQRSPPFSLATALPVLRLLDETLTLEEADLQNAVIIQRLQKTASFRELSEH
What are the official names of this protein?
UBX domain-containing protein 2A, UBX domain-containing protein 4.