PharMolix/UniProtQA huggingface dataset:
Protein: DXS_PROM5
Sequence: MLLSELSHPNQLHGLTVSQLEEIACQIRERHLQVVSTSGGHLGPGLGVVELTLALYQTLDLDFDKVVWDVGHQAYPHKLVTGRFNEFDSLRQQKGIAGYLKRSESIFDHFGAGHASTSISAALGMAIARDAKGENHKCVAVIGDGALTGGMALEAINHAGTLPETPFLVILNDNDMSISPPVGALSTYLNKVRLSPPLQFLSNSVQESVKNIPLIGKDLPEELKTIKGSVRRLAVPKVGAVFEELGFTYMGPIQGHDISNLINTFNAAHRLKKPVLVHVVTTKGKGYPYAEADQVGYHAQSSFNLTTGKSIPSSKPKPVSYSKIFGQTLLKICEQDSKVIGITAAMATGTGLDLLQKNIPEQYIDVGIAEQHAVTLAAGMSCDGLKPVVAIYSTFLQRAFDQLIHDVGIQNLPVSFVLDRAGIVGADGPTHQGQYDISYMRSIPNFVLMAPKDEAELQRMLITSINHKGPTALRIPRGSGRGVAVMDEGWEPLNIGEGEILEDGEDILIVAYGSMVSSAIETSKLLKDKNISPCVINARFVRPLDKDLILPLANKIKKVVTMEEGTLIGGFGSAIVELLNDNDINIPVFRIGIPDVLVDHASPDQSKTQLGLMPNQMSENIINRFNLIKNF
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: DAPE_BURM9
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWRSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PYRK_PYRAB
Sequence: MLRRVMIKETWEVAKNVRAFRFDEKLDFIPGQFIMLWLPGINEKPFSLADKDLIVVKKVGPFTSKLFKLEEGDYVWIRGPYGNGFKSVEGKVALVAGGIGIPPIYALAKYGNLEEKVLIYGARSKEELATLDIENYVDEVVITTDDGSAGIKGFPTDVLARRKVEFSQVYACGPEVMLAKVLEIMNYERTQISAERYMKCGIGICGSCALGPYLVCRDGPVFTGEQLKGTEIGKFSRLPDGRIKSLR
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: TAT_HV1C4
Sequence: MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAHQDSQNHQASLSKQPSSQTRGDPTGPKEPKKEVEREAETDPLD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: ATPB_SALHS
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CD48B_ARATH
Sequence: MLETESSVCDNIAGNEKWRAEAEIGGNERALQALRELIIFPFRYPLEARTLGLKWPRGLLLYGPPGTGKTSLVRAVVQECDAHLIVLSPHSVHRAHAGESEKVLREAFAEASSHAVSDKPSVIFIDEIDVLCPRRDARREQDVRIASQLFTLMDSNKPSSSAPRVVVVASTNRVDAIDPALRRAGRFDALVEVSTPNEEDRLKILQLYTKKVNLDPSVDLQAIAISCNGYVGADLEALCREATISASKRSSDSLILTSQDFKIAKSVVGPSINRGITVEIPKVTWDDVGGLKDLKKKLQQAVEWPIKHSAAFVKMGISPMRGILLHGPPGCSKTTLAKAAANAAQASFFSLSCAELFSMYVGEGEALLRNTFQRARLASPSIIFFDEADVVACKRGDESSSNSSTVGERLLSTLLTEMDGLEEAKGILVLAATNRPYAIDAALMRPGRFDLVLYVPPPDLEARFEILQVHTRNMTLGDDVDLRKIAEETDLFTGAELEGLCRESGTVSLRENIAATAVFNRHFQTAKSSLKPALTIEEVETYSSFRKAAKRSDSKPIPINKKKATSTVFGFSWQLGVLSLLLLATGNYYFNHTKHELLVASAT
What is the function of this protein?
Probably functions in cell division and growth processes.  Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity).
What are the official names of this protein?
Cell division control protein 48 homolog B, AtCDC48b.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, phragmoplast. Note=Primarily localized to the nucleus and, during cytokinesis, to the phragmoplast, a site where membrane vesicles are targeted in the deposition of new cell wall materials.
Protein: RIBBA_BACCZ
Sequence: MFHRIEEALEDLKQGKVVIVCDDENRENEGDFIALAEYITPETINFMITHGRGLVCVPITEGYAERLQLEPMVSHNTDSHHTAFTVSIDHVSTTTGISAHERATTIQQLLNPASKGADFNRPGHIFPLIAKEGGVLRRAGHTEAAVDLAQLCGAEPAGVICEIINEDGAMARVPDLLQCAKQFDIKMITIEDLIAYRRHHETLVTREVEITLPTDFGTFQAIGYSNSLDTKEHIALVKGDISTGEPVLVRVHSECLTGDVFGSCRCDCGPQLHAALAQIEREGKGVLLYMRQEGRGIGLLNKLRAYKLQEEGFDTVEANEKLGFPADLRDYGIGAQILKDLGLQHLRLLTNNPRKIAGLQGYDLTVTERVPLQMPAKEENKTYLQTKVNKLGHLLNL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: CRCB_KORVE
Sequence: MAIREYLWVSLGGIVGACARYFLSRFTAKITGTSFPWGTLLINITGSFVLGLFLVYTTERVFVDPKWRLLIAIGFCGAYTTFSSYAYESMVYFQQGNWGLFAGNVLANNILCLAAVLGAGALVRSI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCH1_CHRVO
Sequence: MSFTDDHDHAACQRPLERVRPFDAAAFERAVADMLTASGIAIDPIHTGKTAQRVRELWQKRLLDGYDTVPAEALGSGFADERRDMVVIRSLAVHGMCPHHLLPFRGVAHVAYLPGGRLHGFGRIARMVDAISHRYTYQEWITHEIARTLVEHGEARGAACLIEAEQLCLLMGENRRGDERVITQCYAGDFETDAEARNQFLRAIER
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: EFG_BACSU
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVGTLRDRLQANAHAIQLPIGAEDNFEGIIDLVENVAYFYEDDLGTRSDAKEIPEEYKEQAEELRNSLIEAVCELDEELMDKYLEGEEITIDELKAGIRKGTLNVEFYPVLVGSAFKNKGVQLVLDAVLDYLPAPTDVAAIKGTRPDTNEEIERHSSDEEPFSALAFKVMTDPYVGKLTFFRVYSGTLDSGSYVKNSTKGKRERVGRILQMHANSREEISTVYAGDIAAAVGLKDTTTGDTLCDEKDLVILESMEFPEPVIDVAIEPKSKADQDKMGIALAKLAEEDPTFRTQTNPETGQTIISGMGELHLDIIVDRMKREFKVEANVGAPQVAYRETFRTGAKVEGKFVRQSGGRGQFGHVWIEFEPNEEGAGFEFENAIVGGVVPREYIPAVQAGLEDALENGVLAGFPLIDIKAKLFDGSYHDVDSNEMAFKVAASMALKNAVSKCNPVLLEPIMKVEVVIPEEYMGDIMGDITSRRGRVEGMEARGNAQVVRAMVPLAEMFGYATALRSNTQGRGTFTMHMDHYEEVPKSVAEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G, Vegetative protein 19, VEG19.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PABL_STRGR
Sequence: MVPVHAHDYVTDPPSTTGRTLDGLTLPRVFADAVHRGGDAVALVDGEYALTWSAWRTAVDALARGLQESGVVSGDVVALHLPNSWEYLTLHLAAASVGAVTMPVHQGNAPSDVRALLERVRPAAVVLTARTQEGGGPLTGPALREVLPELRAVLVTGDAAGEGTETVTEMLERWSGEDPLPVEVRPDSPFLLLPSSGTTSARPKICLHSHEGLLTNSRAATEDTADAYAGTLITACPLTHCFGLQSAYSALFRAGRQVLLSGWDVGRFLELARRERPSVVVAVPASCTTWSPGCARTRTAPASARPD
What is the function of this protein?
May be a p-aminobenzoic acid-CoA ligase that activates PabA to start the biosynthesis of candicidin.
What are the official names of this protein?
Protein Y, ORF-3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GPH_YERPS
Sequence: MVKFKAIRGVAFDLDGTLVDSAPGLARAIDMALAHQGLPAAGEALVSTWIGNGADVLVERALHWAGREHNAQLVAQTRELFDHYYAKTVEQGSQLFPQVKATLAQLAANGLPIGLITNKPTPFVAPLLTSLGIADYFSVIIGGDDVVVKKPHPAPLYLLLGKLGLHAREMLFVGDSRNDIMAAQAAGCPCIGLTYGYNYGEAIATSHPDCVLAHFADLLPAIGLPSLKDQEV
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: CHSS1_HUMAN
Sequence: MAARGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEGCRSGQAAASQAGGARGDARGAQLWPPGSDPDGGPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVQFFSSEGSDTSVPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHQAITLHPNKNPPYQYRLHSYMLSRKISELRHRTIQLHREIVLMSKYSNTEIHKEDLQLGIPPSFMRFQPRQREEILEWEFLTGKYLYSAVDGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEELDAQELAKRINQESGSLSFLSNSLKKLVPFQLPGSKSEHKEPKDKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTTEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTQQLAEMWLEKNDPSYSKSSNNNGSVRTA
What is the function of this protein?
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity.  Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer.  Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
What are the official names of this protein?
Chondroitin sulfate synthase 1, Chondroitin glucuronyltransferase 1, Chondroitin synthase 1, ChSy-1, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1, N-acetylgalactosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
Protein: HSLU_PASMU
Sequence: MSEMTPREIVSELDQHIIGQADAKRAVAIALRNRWRRMQLQEPLRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAMKLVRQTEIEKNRFRAEEAAEDRILDALLPPAKNQWGQVETTDSNNTTRQVFRKKLREGQLDDKEIDIDVAAPSMGVEIMAPPGMEEMTNQLQSMFQNLSSGQTKKRKMKIKDALKTLIDDEAAKLINPEDLKQKAIDAVEQNGIVFIDEIDKICKKGEYSGADVSREGVQRDLLPLVEGTTVSTKHGMVKTDHILFIASGAFQVARPSDLIPELQGRLPIRVELSALSAVDFERILTEPNASLTEQYKALMATEGVNIEFTGESIKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFNASDMQGQVVRIDEAYVMDALGDVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STRPN
Sequence: MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: APOC4_CERSS
Sequence: MSLPGRRPWALPSFCFYVLVLAWVVACQQEVPTGSPSPPPGRASGLWGLVRGKVKEFMEPLVTKTRERWRWFWGPSAFRDFMQTYYDDHLRDLRPRAQAWLRSSKESLLNKAYNMCPQLLCGDRDQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DREB_CHICK
Sequence: MAGVGFAAHRLELLASYQDVIGEDSPTDWALYTYEDGSDDLKLAASGGGGLLELSGHFEIQKVMYGFCSVKEPQAVLPKYVLVNWVGEDVPDARKCACASHVAKIAEFFQGVDVIVNASSVEDIDPGAIGQRLSNGLARVSSPVLHRLRLREDENAEPVGTTYQKTDATVEMKRLNREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERLEQEERERRYREREEQIEEHRRKQQSMEAEEARQRLKEQSIFGEQQEEDDRQQLRKSESEVEEAAAIIAQRPDNPREFFKQQERVASGSGDAISPGSHRTGRLHCPFIKTADSGPPSSSSSSSSPPRTPFPYITCHRTPNLSSFFPCSQSDYRKVSAAGCSPCESSPASTPLGEQRTRAPAEETPATPKDSPSPSTQVAEPAATEQHWPFPGPEDKAAEPPGDEPDPDPRPAWTAGADVLGDLVTLEPSEPSPAPAASEPQPVETPGVAEPLIELWQSDGAAPAATSTWPLPDTPAGPPVPPEEGTLLGLDELPEPPATFCDAEQHEEVEEEEEEEEATAGEPHPTGLGYQEGYQEGPEVPPITNGEMGPKDGTAGRGEQASEGYFSQSQEEEAPPPEEPSAKAPQPVFYNKPPEIDITCWDTDPLPEEEESFGGGL
What is the function of this protein?
Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity).  Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity).  Involved in synaptic plasticity (By similarity).
What are the official names of this protein?
Drebrin, Developmentally-regulated brain protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection. Cell projection, growth cone.
Protein: RL39_HALWD
Sequence: MGKKSKAKKKRLGKLEKQNSRVPAWVMLKTNMEVTRNPKRRNWRRSDTDE
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: SYI_CHLAB
Sequence: MHTEGEGSKESLASREERILNFWKTQEIFQKSLKNREGRTLYSFYDGPPFATGLPHYGHLLAGTIKDVVGRFATMDGYYVPRRFGWDCHGVPVEYEVEKSLNLTTPGAIEDFGVAKFNEECRKIVFRYVDEWEHYIYRVGRWVDFSATWKTMDASFMESVWWVFRSLYDQGLVYEGVKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVIKFALHGDPGSLLVWTTTPWTLVSNMAVAVGPEITYVRVADKVSGEQWILGQGCLSRWFSDPDTYEVIESFPGTALIGKSYEPPFNFFEQKRAEGAYTILPGSFVEESEGTGVVHMAPAFGEADFFVCKEHHVPMVCPVDNHGCFTEEIPEYQGQYIKSCDKGIIKSLKNQGKVFYHGTVVHRYPFCWRTDTPLIYKTVNSWFISVEKIKDKMLQANKKIHWVPEHIKEGRFGKWLEGARDWAISRNRYWGTPIPVWKSKDGDILVIGSVEELEKLTGEKVSDLHCHFVDQLKIEKDGKSFHRVPYVFDCWFDSGAMPYAQNHYPFENQKETESGFPADFIAEGLDQTRGWFYTLTVISAALFDQPVFKNAIVNGIVLAEDGNKMSKRLNNYPSPMSIMNTYGADALRLYLLDSVVVKAEDLRFSDKGVESVLKQVLLPLTNVLSFFKTYTDLYGFDANNYDKEEISYSEIDRWILSNLYTVVGKVRESMSSYNLNTAVNPFVTFIDDLTNWYIRRCRRRFWESADTPDRRAAFATLYEVLTVFCRVIAPFIPFISEDIYQQIKTENSLESVHLCDFPYIDLAKVFPDLEQRMGDAREIVGLGHSLRKEHKLKVRQPLANFYVVGPKDRLDQLDSFKQLISEELNVKNIVFYKEAPSFVKTTVKPNFRSLGRRVGEKIKDIQKALASLSQAQIQQLLTQEYLSLNLGSEEIVLHMEDVLISWETDPGYVARSSSLFTVVLDCQLTEELVVEAISRELVNKINTMRRNQKLHVSDRIVLRMQTSEEVRKAFLHYADYICEETLTTQSEFADVLEGEEWDINGHPTVIAIEVAARPH
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_BORT9
Sequence: MGNNPSALKRARQNLKRNLRNVSVKSELKTIEKRCMNLIREGKKEEALEFFKFVSKKLDTAARKRIIHRNKAARKKSNLSILLLR
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MURB_CERS5
Sequence: MMPPVRGTLTEGRPLADLTWLRVGGPADWLFQPADEEDLAGFLAAHDPAVPVFPMGVGSNLIVRDGGLRAVVIRLGRGFNGIRVEGERVIAGAAALDAHVARRAAEAGRDLTFLRTIPGTIGGAVRMNAGCYGSYVADHLIEVRAITREGRAVTLPAADLGLAYRQSRLPEGWVLVEAAFRADAGDPAALARRMDEQIARRDSSQPTRDRSAGSTFRNPAGFSSTGRADDTHELKAWKLIDEAGMRGARRGGAQMSEMHSNFLINTGGATAADLEGLGEEVIKRVFQSSGIELQWEIMRVGEEPVNKQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_BACAN
Sequence: MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSGLVMAGVCCLNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILLLGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNTVVGSISGAVPPLIGWAAIDPSLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVCLLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VCIP1_HUMAN
Sequence: MSQPPPPPPPLPPPPPPPEAPQTPSSLASAAASGGLLKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGKDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRTDKNYSFPLNNLVCSYDSVKDVLVPDYGMSNLTACNWCHGTSVRKVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDSSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHTVKQEDIAVTGKLSSKELQEQAEKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYSIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARETSVVRKHNTGTDFSNSSTKTEPSVFTASSSNSELIRIAPGVVTMRDGRQLDPDLVEAQRKKLQEMVSSIQASMDRHLRDQSTEQSPSDLPQRKTEVVSSSAKSGSLQTGLPESFPLTGGTENLNTETTDGCVADALGAAFATRSKAQRGNSVEELEEMDSQDAEMTNTTEPMDHS
What is the function of this protein?
(Microbial infection) Regulates the duration of C. botulinum neurotoxin type A (BoNT/A) intoxication by catalyzing deubiquitination of Botulinum neurotoxin A light chain (LC), thereby preventing LC degradation by the proteasome, and accelerating botulinum neurotoxin intoxication in patients.
What are the official names of this protein?
Deubiquitinating protein VCPIP1, Valosin-containing protein p97/p47 complex-interacting protein 1, Valosin-containing protein p97/p47 complex-interacting protein p135, VCP/p47 complex-interacting 135-kDa protein.
Protein: S36A3_RAT
Sequence: MGKTPLLREDGRCQRNTFGGSKASSKGSSSSSSNNTVSSKKKPRRKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEYLIQIPHHSHLPLVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFPAVLYLGMSFVIFLYICLGTLGYMKFGADTQASITLNLPNCWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRASENWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIATFYSENISCTTIAKDIMISILGLLGCVLGTYQALYEMTQQSRFPMLNSTNVHT
What are the official names of this protein?
Proton-coupled amino acid transporter 3, Proton/amino acid transporter 3, Solute carrier family 36 member 3, Tramdorin-2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.