PharMolix/UniProtQA huggingface dataset:
Protein: LSM6_MAGO7
Sequence: MENGTMTQGEGKDPTSFLGEIIGNMVTVKLNSGVIYKGELQSVDGYMNIALEKAEEWVAGQKKRSYGDAFVRGNNVMYIAASP
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VIP1L_ARATH
Sequence: MEMEEGASGVGEKIKIGVCVMEKKVFSAPMGEILDRLQSFGEFEILHFGDKVILEDPIESWPICDCLIAFHSSGYPLEKAQAYAALRKPFLVNELDPQYLLHDRRKVYEHLEMYGIPVPRYACVNRKVPNQDLHYFVEEEDFVEVHGERFWKPFVEKPVNGDDHSIMIYYPSSAGGGMKELFRKIGNRSSEFHPDVRRVRREGSYIYEEFMATGGTDVKVYTVGPEYAHAEARKSPVVDGVVMRNTDGKEVRYPVLLTPAEKQMAREVCIAFRQAVCGFDLLRSEGCSYVCDVNGWSFVKNSYKYYDDAACVLRKMCLDAKAPHLSSTLPPTLPWKVNEPVQSNEGLTRQGSGIIGTFGQSEELRCVIAVVRHGDRTPKQKVKLKVTEEKLLNLMLKYNGGKPRAETKLKSAVQLQDLLDATRMLVPRTRPGRESDSDAEDLEHAEKLRQVKAVLEEGGHFSGIYRKVQLKPLKWVKIPKSDGDGEEERPVEALMVLKYGGVLTHAGRKQAEELGRYFRNNMYPGEGTGLLRLHSTYRHDLKIYSSDEGRVQMSAAAFAKGLLDLEGQLTPILVSLVSKDSSMLDGLDNASIEMEAAKARLNEIVTSGTKMIDDDQVSSEDFPWMTDGAGLPPNAHELLRELVKLTKNVTEQVRLLAMDEDENLTEPYDIIPPYDQAKALGKTNIDSDRIASGLPCGSEGFLLMFARWIKLARDLYNERKDRFDITQIPDVYDSCKYDLLHNSHLDLKGLDELFKVAQLLADGVIPNEYGINPQQKLKIGSKIARRLMGKILIDLRNTREEALSVAELKESQEQVLSLSASQREDRNSQPKLFINSDELRRPGTGDKDEDDDKETKYRLDPKYANVKTPERHVRTRLYFTSESHIHSLMNVLRYCNLDESLLGEESLICQNALERLCKTKELDYMSYIVLRLFENTEVSLEDPKRFRIELTFSRGADLSPLRNNDDEAETLLREHTLPIMGPERLQEVGSCLSLETMEKMVRPFAMPAEDFPPASTPVGFSGYFSKSAAVLERLVNLFHNYKNSSSNGRS
What is the function of this protein?
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4.  PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis.  Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.  Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4 (PubMed:25231822).  Probably involved in vitamin E homeostasis via the regulation of gamma-tocopherol biosynthesis (PubMed:17077148).  Catalyzes the conversion of InsP7 to InsP8.  Regulates jasmonic acid (JA) perception and plant defenses against herbivorous insects (e. g.  P. rapae) and necrotrophic fungi (e. g.  M. brassicae, B. cinerea and A. brassicicola) by triggering the production of jasmonate-induced pools of InsP8 and subsequent activation of SCF(COI1) E3 ubiquitin ligase complexes with JAZ proteins (e. g.  TIFY10A/JAZ1) (PubMed:25901085).
What are the official names of this protein?
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase VIP1, Probable protein QUANTITATIVE VITAMIN E-7, Protein VIP HOMOLOG 2, VIP1 homolog protein 1, Arabidopsis homolog protein of yeast VIP1 1, AtVIP1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FTHS_ACTP2
Sequence: MKSDVEIAQAATMQPIHKIAEKLGLNADQIEQYGKYKAKINPTDAFKLPAKNGKLILVTAINPTPAGEGKTTVTIGLTDALNQLGKNAVVAAREPSLGPVFGVKGGAAGGGYAQVLPMEDINLHFTGDFHAITSANNLLAALLDNHIYQGNALNIDTKRVLWRRVIDMNDRQLRNVLGGLGNPTDGVIRPDGFDITVASEVMAIFCLAKDLADLKTRLGNILVAYTKDKQPVYAKDLNAHGAMAALLKDAIKPNLVQTIEGSPAFIHGGPFANIAHGCNSVTATRLALHLGDYAVTEAGFGADLGAEKFCDIKCRLADLKPDVAVVVATVKALKYNGGVEKANLAEENLTALQQGLPNLLKHISNLKNVFGLPVVVALNRFVSDTDAELALIQTACAKQGVEVSLTEVWGKGGAGGVDLAQKVLKAIDEQENRFNFVYDVNESVQNKIKAIAQKIYGADDVNFSAEALAEIKNLEKLGLDKLPICMAKTQYSLSDNAKLLGCPSGFTVTVRSISVSAGAGFIVAICGSIMRMPGLPKVPAANRIDVDENGLITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: KDSB_COLP3
Sequence: MTASDPSVLSKPATGDTSFVVVIPARYQSSRLPGKVLADIDGKPMIQWVVEKAQLSGARQVIVATDNDEVAAVVNSFGAEVCKTRADHQSGTERLAEVMEKYQFSDDEIIVNVQGDEPFIPPDNIAQVANNLANQQQSSHVARMSTLAINIDSVDEAFNPNAVKVILDKDGYALYFSRATIPYDRERFLNSDATTEENIRAIGDFYLRHVGIYAYRAGFIKDYVNWPTSELEQVEALEQLRVLYQGERIHVAVANSHVPVEGVDTPEDLAKARAYATSLV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_HALMA
Sequence: MSNQERQERPEKDPDLRSTEVTEGYEKAPHRAMFRAMGYDDEDLSSPMIGVANPAADITPCNVHLDDVADAAYDGIDDTEGMPIEFGTITISDAISMGTEGMKASLISREIIADSVELVTFGERMDGIVTIGGCDKNMPGMMMAAIRTDLPSVFLYGGSIMPGEHDGREVTIQNVFEGVGAVADGEMSEGELDEMERHACPGAGSCGGMFTANTMASISEALGFAPLGSASPPAEHESRYEEARRAGELAVEVVQERRSPSDFLTRESFENAIALQVAVGGSTNAVLHLLALAAEAGIDLDIETFNEISARTPKIADLQPGGERVMNDLHEVGGVPVVLRALNDAGLLHGDALTVTGNTIAEELEQIDPPTVEDLDVDYLNTVEDPIHERGAIRILSGNLAPDGAVIKITGEDHLHHEGPVRVFEQEEGAMEYVQEGHVESGDVICIRNEGPQGGPGMREMLGVTSAVAGQGHAEDVALFTDGRFSGATRGFSIGHVAPEAFVGGPIAALEDGDTITIDIDDHELSVDLTEDEMQQRLEGHDPEPTYDSGVLAKYHNDFGSAANGAVTNPGAKWD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL3_PYRCJ
Sequence: MGLKINRPRRGSMGVYPRKRAADIVPRVRTWPEVNLGKPTLLGFAAYKAGMLHAVVVDDRPTSPLYGKEVVKAVTVLDAPPLYVAAVRLYTLDPTNGYKVAVGEAWVSEPPADLRRVLTLPEKFDTEKQLKALEEYRDVAVDVRVLVATQPRLSGIGKKTPEVLEIPVGGVPSIDERINFAISLLGKTVSPKDVFTPGQLVDVIAVTKGKGYQGVVKRFGVTILPRWHKHRKGHRRTGTIGPQAPALMFTQPRPGQMGFHQRTEYNKRILKIGDNGAEITPKSGFPHYGVIKGPYILLQGSVPGARKRLVVLRYPVRPPKKAPPAAEPQVVWVSSQSI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PSAJ_CERDE
Sequence: MRDIKTYLSVAPVISTLWFGSLAGLLIEINRLFPDALVFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ERA_THEP3
Sequence: MGHKAGFVALVGRTNVGKSTLLNAILQEKIAITSPKPQTTRNTIRGILTTDEYQVIFVDTPGIHKPKSKLSEFMIEVAKRTLKEVDLILYMIEPDTEVGPGDRYIIEHLKEVDTPVILVVNKIDLVPEKRVEETIKIFKEQYEFKDVVAISAIENKNIDLLKEKIVSLLPEGPKYYLDDYITDQPEKLIVAEIIREKMLHFLEEEVPHGVYVEVESIKEREDKDIIDIEAYIYCEKESHKGIIIGKNGQMLKKIGQSARLDLEEFYGKQVFLDLWVKTRKGWRDNTTLLKKLGYAIDKKTYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: ALKB8_MACFA
Sequence: MDSSHQSNYKLSKTEKKFLRKQIKARHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQLLPVLEKCGLVDALLMPPNKPYSFARYKTTEESKRAYVTLNGKEVVDDLGQKIILYLNFVEKAQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDKDKPLPGGLPDICDSFLEKWLREGYIKHKPDQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGTAVPVMLPRRSLLVMTGESRYLWTHGITCRKFDTVQASENHKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSFPESDEEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKYLGVNKELYMVGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLKGNRNSQGKKEEMNSDTSVQRSLVEQMPDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPIHVNRTSFYSQDMLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEALCRTVSDVRILQSYYDQGNWCVILQKA
What is the function of this protein?
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain.  Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA.  Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys).  Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly).  Required for normal survival after DNA damage.  May inhibit apoptosis and promote cell survival and angiogenesis (By similarity).
What are the official names of this protein?
Alkylated DNA repair protein alkB homolog 8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: FBPC_PASMU
Sequence: MSNNDFLVLKNVTKAFGKAVVIDNLDLSIKRGTMVTLLGPSGCGKTTVLRLVAGLESPTSGQIFIDGEDVTKSSIQNRDICIVFQSYALFPHMSIGDNVGYGLKMQGVSKEERAKRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALVLKPKVLLFDEPLSNLDANLRRSMREKIRELQQRLGITSLYVTHDQTEAFAVSDEVIVMHKGKIMQKAPAKELYLRPNSLFLANFMGESSIFQGTLQQDQVTVNGYQFKLNNAAQFGLTDGACLVGIRPEAISFKETGEAAQRCSIKSAVYMGNHWEIVANWGGQDLLVNTNPEQFNPELKEAYVHLAEHGVFLLKPE
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOC_THEFY
Sequence: MLDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMVTWVDTEARERDLPSLEAQISVERQHLEQRRDSAIEERHRKLEADLAELEEQGAKADARRKVREAAEREIRQIRDRAQREIDRLEEVWNRFKNLKVQDLEGDEQLYREMRDRFGKYFRGGMGAQAIKERLANFDLEAEAEKLREIIRTGKGQKKARALKRLKVVSAFLNTRNSPMGMVLDCVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKQMALELFKPFVMKRLVDLNHAQNIKSAKRMVERARPVVWDVLEEVISEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARILMLATNNILKPSDGKPVTMPTQDMVIGLYYLTTMKEGAKGEGRAFSNIGEAIMAYDLGELDLQAKIKLRVEGDTVPPVNWEPPEDYQPGQPYILETTLGRYLFNETTPEDYPFVNQQMGKKQLSALVTELAEKYSKVQVATTLDALKDAGYYWATRSGLTISISDVIPPPNKQQILDKYEQQAQKIQRQYERGLISDDERRQELIHIWTKATDEVAKDMEENSPPDNPVWMMVNSGSRGNPLQVRQIAAIRGLVSNTKGETIPRPIKSSYREGLTVLEYFISTHGQRKGLADTALRTADSGYLTRRLVDVAQDVIVREVDCGTDRFLWQEIGERRPDGTIVRKHNVENTGFGRTLAEDVVVDGKVIATKLSDTTEALIDKLLAAGVTRIRIRSALVCESKIGVCATCYGRSLATGKPVDVGEAVGIIAAQSIGEPGTQLTMRTFHMGGTAGQDITHGLPRVQELFEARVPKGVAPISEVEGRVRIEETDKSRKIIVVPDDGSDEVSYQVPMRAPLLVQDGQRVEVGQQLVQGTVNPHEILRILGPRAVQQHLVSEVQEVYKSQGVSIHDKHIEIIVRQMLKRVNVLESGDTKLLPGEMIERPKFEEINRRVVAEGGQPASARPVLLGITKASLATESWLSAASFQETTRVLTENAIHGKSDPLLGLKENVIIGKLIPAGTGMPQYRNIRVEPTEEAKASMYSVSSYEEPSEYTFGQGSGEAVPLEDYDFGSYNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RPIA_SALPK
Sequence: MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKGLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQNVVTDNGNVILDVYGMEILDPIALENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SERC_LARHH
Sequence: MTIYNFSAGPALLPQDVLREAQRELTDWHGSGMSVMEMSHRGREFMSIHARAEADLRELLQIPDNYRVLFLQGGAHSQFSMVPMNLLRGKTTADYVITGHWGKVAIKEARCYGDMRIAATGEASGFNGIPPQSEWQPNPDAAYLHYVSNETIGGVQFPFIPESGVPLVCDMSSDFLSRPVDVSRFGLIFAGAQKNIGPAGLTLVIVREDLLGQTLPGTPTMFDYKIHADADSMYNTPPTYAIYMAGLVFQWLKDNGGVRGIQMRNEEKAGLLYHTIDSSDGFYRCPVDVECRSRMNVPFRLRTEVLEKRFVDEADMAGLLQLKGHRSVGGVRASIYNAMPFEGVKALVAFMAEFARRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16A_CONMR
Sequence: MKLTCMMIVAVLFLTAWTLVMADDSNNGLANHFSKSRDEMEDPEASKLEKRACRKKWEYCIVPIIGFIYCCPGLICGPFVCV
What is the function of this protein?
MuO-conotoxins are gating-modifier toxins that inhibit sodium current by trapping the domain II voltage sensor in the closed position to prevent opening of the sodium channel.  This toxin inhibits rNav1. 2/SCN2A (IC(50)=532 nM), rNav1. 4/SCN4A (IC(50)=438 nM) and rNav1. 7/SCN9A (IC(50)=345 nM) (PubMed:10627583).  It blocks Nav channels by interacting mainly with the C-terminal part of the pore loop of domain-3 (PubMed:16458302).  It does not bind on site 1 (PubMed:8890263).  At small concentration, this toxin also acts as a calcium current agonist, whereas at higher doses it blocks fast-inactivating calcium current (PubMed:7727394).
What are the official names of this protein?
Mu-conotoxin MrVIA, Conotoxin Mr6.5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: INTR_SACER
Sequence: MEQKRTRNPNGRSTIYLGNDGYWHGRVTMGIGDDGKPDRRHVKRKDKDEVVEEVGKLERERDSGNVRKKGQPWTVERWLTHWVESIAPLTCRYKTMRGYQTAVYKHLIPGLGAHRLDRIQNHPEYFEKFYLRMIESGLKPATAHQVHRTARTAFGEAYKRGRIQRNPVSIAKAPRVEEEEVEPLEVEDMQLVIKAALERRNGVRYVIALALGTRQGESLALKWPRLNRQKRTLRITKALQRQTWKHGCSDPHRCGATYHKTEPCKAACKRHTRACPPPCPPACTEHARWCPQRTGGGLVEVDVKSRAGRRTVTLPDQLFDLILKHEKLQGAERELAGTEWHDGEWMFTQPNGKPIDPRQDLDEWKAILVEAGVREARLHDARHTAATVLLVLGVPDRVVMELMGWSSVTMKQRYMHVIDSVRNDVADRLNTYFWGTN
What is the function of this protein?
Is a recombinase (or integrase), catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Integrase, Recombinase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: GPMA_GLAP5
Sequence: MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKAAGKKLLDAGYEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYAHLPKDVVPNAENLKITLERVLPFWEDQIAPALLSGKRVLVTAHGNSLRALAKHIIGISDEEIMDFEIPTGQPLVLKLDDKLNFVEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RECF_ANADE
Sequence: MKLLSLHVQDFRNLAAVELAPSPRATVLLGENGQGKTNLLEAIYFLTTLKPLRAVRLAELVRFGAADAAVAGDFEGPGGVRRVAVQVAAGGRTASLDGKALGSGARLDDYFEGLASVCFSPDDLLLVKAGPDGRRRFLDRAAFNRWPAVLGEAREYVRALRARNAALRSGTAEVEASFREPLVRAGARLLVRRRDLVAELAPRLRAAFAEISGPAAPEADLAYRAAGGVEVGHPEAEVAARLARALETRLERDREKGFTSAGPHMDDLVLALGGKGARLYGSQGQQRALVLALKIAEIENLRAALGRPPLLLLDDVSSELDPAKNRFLLGYLAALPAQAFLTTTDRRLIEPAAGPDTAFYEVRSGVVSPLVS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG8L_DICDI
Sequence: MALLSKSFKQEYSLEKRKLISSKIRNRYKDRLPIIVERAANSDVPDINKKKFLAPSNMVITNFIMEIRKHLDDSDHNEQKAIFLFVNKNNLPPSSQLLSSIYDAHKDEDGFLYICYSGENTFGSDI
What are the official names of this protein?
Autophagy-related protein 8-like protein DDB_G0290491.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: CALX2_ARATH
Sequence: MRERIITFVSLLLVALLSFPSVSYCDDQTILYESFDEPFDGRWVVSEKAEYQGVWKHEKSEGHDDYGLLVSEKAKKYGIVKELDVDEPLNLNEGTVVLQYEARFQEGLECGGAYLKYLRPQEAGWVPQGFDNDSPYSIMFGPDKCGATNKVHFILKHKNPKSGEFVEHHLKFPPSVPFDMLSHVYTAVLKSDNEVRILVDGEEKKKGNLLSAEDFEPPLIPSKTIPDPEDKKPEDWDERAKIPDPNAVKPDDWDEDAPMEIEDEEAEKPEGWLDDEPVEVEDPEASKPEDWDDEEDGEWEAPKVSNTKCEAAPGCGEWKRPMKRNPAYKGKWSSPLIDNPAYKGIWKPRDIPNPDYFELERPNLEPIAAIGIEIWTMQDGILFDNILISKDEKVAETYRQSTWKPKFDVEKEKQKAEDEAAGEADGLKSYQKKVFDLLYKVADISFLSAYKSKIMELIEKAETQPNLTIGVLISIVIVFLSLFFKLIFGGAKAKVEKKKPETAAETSTSEAKTEEKAEAVAAPRKRQTRRES
What is the function of this protein?
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity).
What are the official names of this protein?
Calnexin homolog 2.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL22_SACS2
Sequence: MASWKYPQLDVDELKIAKAVIRDVPESIRDLYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKSNISAKWKIKAGRYPKKAIRQVLKVLENAEANATNKGLDVDKLIIRHIAAHKGITLQRYMPRAFGRATAKYRRTSNIEVILEEVE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CARB_PELTS
Sequence: MPRRKDIRKVLVIGSGPIIIGQAAEFDYAGTQACKALREEGVSVVLVNSNPATIMTDLDIADQVYIEPLAWDSVAEIIARERPDGLLPTLGGQTGLNIAVELSEKGVLQDYGVELLGTPLESIKKAENRELFKNLMLEIGEPVPRSTIAGSVEECLAFAGEIGYPVIVRPAYTLGGTGGGIACREQELVEIAGRGLKMSMIGQVLLEQSVAGWKEIEYEVMRDGADNCITVCNMENVDPVGIHTGDSIVVAPSQTLSDKEYQLLRSAALRIIRALKVEGGCNVQFALDLNSMAYYVIEVNPRVSRSSALASKATGYPIAKVAAKIAVGLTLDEIKNPVTGKTYACFEPALDYVVVKIPRWPFDKFGSADRTLGTQMKATGEVMAIDRTFEGALMKAVRSLEIGVDGLHLPGSAGWSEMELEEKLSYPNDLRLFAIAEAFNRSWGMREVAQLTTIDYFYLSKIRGIVELERELQAAGPRPPRELLRRAKSCGLPDSLIGRLTGLPAREVHALRKEYGILPAFKIVDTCAAEFEAVTPYYYSTYDDEDEVAVSGRPKVLVLGSGPIRIGQGIEFDYCSVHSVWGLQQEGIEAVIINNNPETVSTDFDTADKLYFEPLTLEDVLNVIEKEKPLGVIVQFGGQTAINLTAGLAALGVNILGTPVEGIDAAEDRDKFEKLLTGLGIPQSEGRSAVNVEEAQAVAEKLGYPVLVRPSYVLGGRAMEIISSKTELVKYMTEAVQVSPRHPVLVDKYIRGKEVEVDAIGDGNDLFIPGIMEHIERAGVHSGDSIAVYPPQTLSREEIDKIVEYTLKIGRALKINGLINIQYVVDNGGVYVLEVNPRASRTVPVLSKVTGVPMVQAATRAMLGRSLAELGYRPGLGPVGGFIAVKAPVFSFEKLGLVEISLGPEMKSTGEVMGIDRSFPGALYKAMRAAGLKVASGGRVVFSVADRDKAEAVSIAGEYAALGYTLHATPGTARALEKAGLEVEVVEITDPVPLIRSGTVGLIINTPTRGKVPGRPGFLLRRTAAEYRVPCLTSLDTARALAMVLRSVRWGGEPAPVSMAELFEKEGTANCCLRKKDSKAAIF
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: DTD_TERTT
Sequence: MKVLIQRVTQAAVDVDSITIGQIDAGILALVGVEKQDNRETLGRMAQKLLKYRIFPDSEGKMNLSLTDTGGGLLVVSQFTLAADTRKGLRPSFSSSAPPDLARSLFDEFVAALRAQHPNVETGRFGADMKVRLINDGPVTFMLES
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASG7_YEAST
Sequence: MTTLASSIEHKTKHLAAPFENDENPWMKKYCCQCKSCKMSVPVQPWLPRFFVFGILCPVFWLVNLLAWWFLQYWQPHELEFHDLQEDEYPGFYEYEAITKRTVIPIKEEVLQEIRVMQNFSDSNSEEYYESKDGMPSSFLNVNTEQVEDENDTLKKYRYAFLKKVAHDVLESHDLLRKTFRDWNLRSLLGLLIDSILIIFVVLLCKKSR
What is the function of this protein?
Required for receptor inhibition of inappropriately expressed a-factor receptor (STE3) in MAT a cells.  Inhibits signaling by relocalizing the G protein beta-gamma (STE4-STE18) subunit to intracellular membranes.  May also be a mechanism for the down-regulation of the mating pheromone response after the zygotic fusion event, promoting the transition of the new diploid cell to vegetative growth.
What are the official names of this protein?
Protein ASG7, A-specific gene 7 protein.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein.