PharMolix/UniProtQA huggingface dataset:
Protein: VAB1_CAEEL
Sequence: MRLYNSRILNPHQSIFILVLQCLITIVTSHQEVLFDLSKVGSDLKWDQVSLRHDRDDVWMEETWRNPAATDEKHANQRAYVTCNYDMINPSNWLFSHFIEVKTARRIYIELLFNTRDCDAYLNPKSCKETFSVYLKQFKTSRPGSTKIEKERFSEDIDNWKNIGRLARSNSNMTTETLGMEIDSDTKTIRIAFEEQGICLSLLNVKIYYRICDEFTDQLVYFRPQVTGPKETDMVRMNGSCIPNASKKIPGVDLIGLCMSTGSGIKTSGECVCDSGYSQIADSNGARCESCPTNTYKPKGQSLCKSCPSNSISSEAASSCRCLNGYFRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPVSHLRVDASQSDGITIAWSVSDSDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFIGLNPETVYQFRVRIRDDLRWSQPISYQLGRGLMSSPSSNEVEESQFLNQTGSALLIIIALILIVIAVALCMIVVQKKSKNRKQMSDLDVLDTYKQDSMTPDYHTTSRHHHHQGNLPATLHEQLRSTTKLNAPLIPSFGSPISQPPPYYGGVHPNSGKYKTYVDPTTYEDPYQALIEFTFDISPNDVFITQVIGGGEFGDVCLGGLSKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITHRKFTPSSDVWSFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTFTQLLATFHKYILQPTLIEHDPGELPRRVQSQSALNTYGSVNVGVVPTPPSSAAPMPSLDDFLRQIGLNHVYGQLVSNNIHSVSDLANTSHLDLLAYGLMSAECSTVRDGLNGRISGSPPGSSGTIHATTRGTRTTRPPREEGFFV
What is the function of this protein?
Receptor for members of the ephrin family (By similarity).  Receptor for major sperm proteins (MSPs), that functions as sperm-sensing checkpoint which inhibits oocyte meiotic maturation and ovulation when sperm are not available for fertilization (PubMed:12533508).  Specifically, functions to negatively regulates oocyte maturation and MAPK activation in the absence of MSPs (PubMed:12533508, PubMed:19853560).  Required for the MSP-mediated increase in the basal sheath cell contraction rate in somatic cells (PubMed:12533508).  Phosphorylates phosphatase daf-18/PTEN which probably promotes daf-18 degradation (PubMed:19853560).  By inactivating daf-18, regulates positively insulin-like daf-2 signaling cascade (PubMed:9506518).  Involved in interactions between neuronal substrate cells and a migrating epithelial sheet in head epidermis morphogenesis (PubMed:9506518).  Also required for cell movements following gastrulation and during ventral closure of the epidermis (PubMed:9506518).  Might play a role in spermatheca morphogenesis (PubMed:25529479).  Involved in axon guidance of SDQL neurons during neurogenesis (PubMed:26903502).
What are the official names of this protein?
Ephrin receptor 1, Tyrosine-protein kinase Eph receptor, Variable abnormal protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PYRB_SULIM
Sequence: MRLRHVVSSLDLTRDDYFRIFELADKFSNVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQALIDLYTIYKVFGEIDGRTFGLLGDLKYARTVNSLLRALTRFKPKKIFLISPSQLKVRREILDGLNYPVIETENPYDVIQDIDVLYVTRIQKERFVDELEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRKVDKTTNAKYFYQASLAVPVRMALFYEVLGERKDD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: HDFR_SHIFL
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RS4_PHYAS
Sequence: MSRYTGSTWKISRRLNYSITETGKELRKRAYAPGQHGQRRAKISDYGLQLKEKQKLRFTYGMSEKQFRKTFERASKLKGIHGEMFLVLLESRLDNIVYRLGFAKTRAQARQLVNHGHVLVEGKKVDIASYSLKPGQTITLREKSKNLKIVEEVLKNKFVRADYVSLDKQLNGKYVRYPKRNEFLAEINEQLIVEFYNR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: LPXA_PSEAE
Sequence: MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQC_XANCP
Sequence: MTALLSPDQLEADLRAIGARLYHDQHPFHALLHHGKLNRGQVQAWALNRFEYQRCIPLKDAAILARMEDPALRRIWRQRILDHDGNSPSDGGIARWLHLTDALGLPRELVESGRALLPGTRFAVQAYLHFVREKSLLEAIASSLTELFAPNIIGQRVAGMLQHYDFVSPEALAYFEHRLTEAPRDSDFALDYVKQHADTIEKQQLVKAALHFKCSVLWAQLDALHVAYVSPGVVWPDAFVPERDSKRAAA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: GGAG_MLVAV
Sequence: LGDVSEASGARWVAQSVSPSPDRFGLFGAPPLSEGYVVLLGDERSKPSPPPSEFLLSVFRRNRAARLVCLSIVLSFVCSLLFWTASKNMGQTVTTPLSLTLEHWEDVQRIASNQSVDVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSPSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLSEDPPPYGGQGLSSSDGDGDREEATSTSEIPAPSPIVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVDAAFPLERPDWDYTTQRGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAERIFNKRETPEEREERVRRETEEKEERRRAEEEQKEKERDRRRHREMSKLLATVVSGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Plays a role in viral particle release.  Presumably acts by facilitating the fission of the virion bud at the cell surface (PubMed:17267509, PubMed:22828015).  May prevent the antiviral activity of murine APOBEC3 (PubMed:25505062, PubMed:23671100, PubMed:20702647).
What are the official names of this protein?
Glyco-Gag protein, Gross cell surface antigen, glycosylated Pr80 gag, gPr80 Gag, gag-gPr80.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: SORR1_HYPJQ
Sequence: MGSSATATTTGESTRQQPGLACEECRRRKARCDRVRPKCGICADSGRNCVVLDKRSQRGPKKGQLKDLRSRLMLLEQRLVGQNDAPSLPQERDSLGCPTPSEKVSPEGDLVSSRASTDIGLDTCMGSTAGAFALFGSTSGSDKMPPLTPDLSTASTANSMAACICKGWQTEPAMFSTSPFPQIPLTPQSTTAPSRMPSISLAAADPIMPDVRVHPFAPMVHKRRYYAWASDPNASPARTALRSAMRTIASAMSPQFCDIGHVMYASTRRMLETQDACPETGLPWMTRLKPPHEQRKMHHERIQAWLLLAYYDVLRKSEHQAFITARRAFRLLRLSGLCEMDIDAYSGRQGDVATCTPPAETTWNMQMCSSENGADEAVLQQDWISVEERRRTVWSAFLLDRLSTMVNDQPTMLMEEAVTKPHACTFSWYFSADLPISNQFYTRLPMSEAEFQSGTQEPVSQMGFLIEATDGIKASNSIQPLPPFAHCVVVANLFARCMTHCKMAMQSPPMSAPEAHDFWIRHQWLASAAANACESTETRCDPMLVFTRILAYSASLSLCSTANATSWQTLDHHLMAMACKPAAHQAASEVVRIIKTAPRIAFFKMHPFFPNAIALVTSFLNADVPYLPSTRGGNAMDAIQERQDAVNELLAALRRSSQVNNLAAELLCKLELDIGQAASDGSIYG
What is the function of this protein?
Transcription factor that acts as the main regulator of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria (PubMed:29104566).
What are the official names of this protein?
Sorbicillinoid biosynthetic cluster transcription factor sor4, Sorbicillinoid biosynthetic cluster protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1_CLOB8
Sequence: MSKDDVIEMQGTVLESLPNAMFQVELESGHKILAHISGKLRMNFIRILPGDKVTVELSPYDLTRGRITWRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_TERTT
Sequence: MSDYLVAALYKFVSLPNYESLREPLIDFCQSREIKGTLLLAAEGINGTVAGTPEAIQALLEELRRQPGLDALEHKESVATEQPFYRLKIKLKKEIVTMGVEGIDPNLVVGTYVAPAEWNALISDPDVTVIDTRNDYEYEIGTFRGAVNPNTQSFRQLPQYVAENLDPNKHKKVAMFCTGGIRCEKSTALMKQMGFEEVYHLQGGILKYLEEVPEGNSLWDGECFVFDNRVSVKHGLEEGSYELCHGCRFPINETDKQSDKYIKGVACPRCYDEQTPEQRSRFLERQKQMELASRKGELHIGDRADIAKSRTTQGAPSADGE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LPXK_RICPR
Sequence: MIKLLYPQFWQERNIIAYLLLPISLIYQFLSYLRASLAYPVILPAQVICVGNCSVGGTGKTQIVIYLAKLLKAKNVPFVIITKAYGSHIKSTTIIQKGHTALEVGDEGIMLARYGTVIAAKYVKDILPLINELKPDVIIVDDFLQNPYLHKDFTIVSVDSQRLFGNRFLIPAGPLRQNPKQVLDAADLIFLVSSNQDQIPNELTPYIDKLINAQIVPSNNIDKNKNYFAFSGIGNPQRFFLTLENYRLNIVGYKIFPDHYNYLQADLENLYSLAKEHNAILITTRKDYVKFNYLNDEIICLDVELSINNPDLLNEKIFKKAKILN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GLPK_LACP7
Sequence: MEKYIMALDQGTTSSRCILFNQRGEVCSVAQKEFTQVYPRTGWVEHRPMDIWSSQISVAAEAMAAIGAKAEDIDSIGITNQRETTIVWDKNTGEPVYNAIVWQCHRTADMIEQLKKDGFDSVIRKKTGLIPDAYFSATKIKWILDNVDGVRERAEAGSLLFGTVDTWIIWNLTKGRVHVTDYTNASRTMLFDIHNLCWDDEILTYFKIPKSMLPKVQASSSIFGHTEEGLLGGEILISGAAGDQQAALFGQCCFEPGEVKNTYGTGCFLLMNTGDTAIESQNGLLTTIAAGDAGHIEYALEGSVFVAGAAIQWLRDEQRMIKKASQSEEYAKEVEDTNGVYVVPAFTGLGAPYWNPYARGTIVGITRGFSKEHMIRATLESLAYQTVNVLHAMEQDSNISLKSLRVDGGASANNFLMQFQADVLNTLVYRPQCIETTALGAAYLAGLATGYFKDRNEIKDNWTLGGTFSPQMDEQKRKELLKGWKRAVRCALAWAEDIE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GPN3_YEAST
Sequence: MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAEATKYEFTIDIRDLISLDDVMEEMDLGPNGALIYCFEYLLKNLDWLDEEIGDFNDEYLIFDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSAMILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQCIANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDVEE
What is the function of this protein?
Small GTPase required for proper nuclear localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import (PubMed:23267056).  Promotes sister chromatid separation during anaphase (PubMed:23324351).
What are the official names of this protein?
GPN-loop GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: HIS3_NEIMA
Sequence: MDKNLLEAVKFDEKGLVCAIAQDAETKRILMVAWMNAEALQKTVETGFAHYYSRSRQKQWMKGEESGHTQKVRELRLDCDGDAIVMLIAQNGGIACHTGRESCFYKVWRGGAWETADAVLKDEKEIYGSTH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_PROMH
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAAQMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: COR2A_MOUSE
Sequence: MSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLGIVLQEASYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVPLTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMSLRPGSELLDSQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQAPFSLLEEKLAKWTAEHHLGEKSCLTNGFDVFECSPPKTENELLQMFYRQQEEIRRLRELLIQREVQTKQLELEIKNLRMALGQL
What are the official names of this protein?
Coronin-2A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
Protein: SMRC1_HUMAN
Sequence: MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPVDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP
What is the function of this protein?
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).  Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.  May stimulate the ATPase activity of the catalytic subunit of the complex (PubMed:10078207, PubMed:29374058).  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex).  During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
What are the official names of this protein?
SWI/SNF complex subunit SMARCC1, BRG1-associated factor 155, BAF155, SWI/SNF complex 155 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1.
What is the protein family that this protein belongs to?
Belongs to the SMARCC family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CYOE_XANC8
Sequence: MAVSARDYWDLTKPKVVALIVFTALVGMFLAIPGMPTWLQVRTGALGFLGIWLAASAAAAINQLLDAKIDAQMARTSWRPLVVGKVRPAQVLAFASVLIVISMTILVVWVNVITAVLTFASLIGYAVIYTVYLKRATSQNIVIGGLAGATPPMLGWAAVTGLPTSADWINASLLVLIIFIWTPPHFWALAIFRRADYAKAAIPMLPVTHGVPHTRKQILVYTVLLAIVTLLPVAVGMSGVFYLGGAVVLNAVFLWYAWRMLDPPDELFSMKMFGYSVVYLMALFAFLMVDHLLLPWVR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_NITEC
Sequence: MYAVIKTGGKQYRVQIGNKLKVETLPVEVGSDIQLDQVLMVADGEIVSTGAPLLDQAKVSATVISHGRHDKIRIFKMRRRKHYRKQQGHRQNYTEIQITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GUAA_BRUSI
Sequence: MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALEGESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: YCF68_MAIZE
Sequence: MAYSSCLNRSLKPNKLLLRRIDGAIQVRSHVDRTFYSLVGSGRSGGGPPGLLSSRESIHPLSVYGELSLEHRLRFVLNGKMEHLTTHLHRPRTTRSPLSFWGDGGIVPFEPFFHAFPGGLEKAVINRTSLILPS
What are the official names of this protein?
Uncharacterized protein ycf68, ORF 134.
What is the protein family that this protein belongs to?
Belongs to the ycf68 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SURE_AQUAE
Sequence: MPTFLLVNDDGYFSPGINALREALKSLGRVVVVAPDRNLSGVGHSLTFTEPLKMRKIDTDFYTVIDGTPADCVHLGYRVILEEKKPDLVLSGINEGPNLGEDITYSGTVSGAMEGRILGIPSIAFSAFGRENIMFEEIAKVCVDIVKKVLNEGIPEDTYLNVNIPNLRYEEIKGIKVTRQGKRAYKERVFKYIDPYGKPFYWIAAEEFGWHAEEGTDYWAVLNGYVSVTPLHLDLTNYKVMKSIKYLEDSP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRA_XANCP
Sequence: MAMDFIRIRGARTHNLKNIDLDLPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLSVMEKPDLDHIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARVGQPRCPDHGFPLEAQTVSQMVDHMLTLDPEQRYMLLAPVIRDRKGEHAQVFEQLRAQGFVRVRVDGELYEIDAVPPLALRQKHTIEAVIDRFRPREDIKQRLAESFETALKLGEGMVAVQSLDDATAAPHLFSSKYSCPVCDYSLPELEPRLFSFNAPVGACPSCDGLGVAEFFDPDRVVVHPELSLSAGAVRGWDRRNAYYFQLIASLAKHYKFDVDAVWNTLPAKVRQAVLFGSGDEVISFTYFTDAGGRTTRKHRFEGILPNLERRYRETESPAVREELTKYVSQQPCPACNGTRLNRAARNVFVADRPLPELVVLPVNEALNFFRGLSLPGWRGEIASKIVKEIGERLGFLVDVGLDYLTLERKADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLTRLRDLGNTVIVVEHDEDAIRLADHVLDIGPGAGVHGGEICAQGTLQDILESPRSLTGQYLSGKRRIEIPKQRHKPNPKMMLHLRGATGNNLKNVDLEIPAGLLTCITGVSGSGKSTLINDTLFTLAANEINGASHTVAPHREVENLDLFDKVVDIDQSPIGRTPRSNPATYTGMFTPLRELFAQVPESRARGYSPGRFSFNVRGGRCEACQGDGMIKVEMHFLPDVYVPCDVCHGKRYNRETLEIRYKGFNISDVLQMTVEDALRLFEPVPSIARKLETLVDVGLSYIKLGQSATTLSGGEAQRVKLSKELSRRDTGRTLYILDEPTTGLHFHDIEALLGVLHKLRDEGNTVVVIEHNLDVIKTADWIVDLGPEGGHRGGTILVSGTPEDVAAHKASYTGQFLAKMLPSVKARETRPAAMANKPDARPPRKVKPEKVAKATKTATKKTAKKKAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET3_NEUCR
Sequence: MSNPPHGGVLKDLIARDLPRHAELEAEAETLPALLLSERQLCDLELILNGGFSPLEGFMNQEDYNDVVKENRLASGLLFSMPITLDVSEETISELGLKAGARITLRDFRDDRNLAILTVDDVYKPDKALEAKEVFGGDEEHPAVKFLYETAKEYYVGGKLEAVNKLQHYDFVDLRYSPAEIRTHFDKLGWSRVVAFQTRNPMHRAHRELTVRAARSHHANVLIHPVVGLTKPGDIDHFTRVRVYKALLPRYPNGMAVLGLLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGVDFYGPYDAQYAVEKYRDELGIEVVPFQMMTYLPDSDEYAPVDQIPKGVRTLNISGTELRARLRSGREIPEWFSYPEVVKVLRESHPPRSQQGFTVLFTGYPNSGKDQIARALQVTLNQQGGRSVSLFLGENIRHELSSELGYNREDRDKNIARIAFVASELTRSGAAVIAAPIAPFEKARQNARELVEKYGDFYLVHVATPLEYCEKTDKRGIYAKARAGEIENFTGVNDPYETPAKPDLVVDCEKQSVRSIVHQIILLLESQGLLDRF
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_ECOSE
Sequence: MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.