PharMolix/UniProtQA huggingface dataset:
Protein: LKTB_PASSP
Sequence: MEVNHQSNDLGLVALKMLAQYHNIPLNPEEIKHKFDIEGKGLTLTSWLLAAKSLELKAKHIKKEISRLHLVNLPALVWQDNGKHFLLVKIDTDKKRYLTYNLEQDAPKILSQEEFESCYQGKIILVTSRASIVGQLAKFDFTWFIPAVIKYRKIFLETLLVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNIITVALAIVIIFEIVLSGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLDDKFARGADNQAFLVESVTAINMIKAMAVSPQMTDTWDKQLASYVSSSFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFTQVGISVTRLGDVLNSPTEQYQGKLSLPEIQGDIAFKNIRFRYKPDAPTILNNVNLEIKKGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRENIALSEPGMSMERVIYAAKLAGAHDFISDVREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHNELLQNNNGLYSYLHQLQLN
What is the function of this protein?
Part of the ABC transporter complex LktBD involved in leukotoxin export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).
What are the official names of this protein?
Leukotoxin translocation ATP-binding protein LktB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SERC1_PONAB
Sequence: MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD
What is the function of this protein?
Enhances the incorporation of serine into phosphatidylserine and sphingolipids.
What are the official names of this protein?
Serine incorporator 1, Tumor differentially expressed protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYB_DELLE
Sequence: MTNIRKTHPLMKILNNAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWIIRYLHANGASMFFICLYTHIGRSLYYGSHTSQETWNIGVLLLLMVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFTFHFILPFIITALVAVHLLFLHETGSNNPTGIPSNMDTIPFHPYYTIKDILGALLLILTLLTVTLFTPDLLGDPDNYTPANPLNTPAHIKPEWYFLFAYTILRSIPNKLGGVLALLLSILILLFIPMLQTSKQRSMMFRPLSQLLFWTLIADFLILTWIGGQPVEHPYITVGQLASILYFLLILVLMPVASLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPOL_RSIV
Sequence: MDSVYIYQWLYANYEVRGYGIALNNTVVCVRVPNFKQVVYVECTDPQHDPRSTFTQHGFRVYETPRACSLYGAKGVGTYFAARVPNYNAMRDVQETQGPFKIHESRVSKTMEFTARAGLPTVGWIQVSQRCVVTRTVTMAAKEYMVPNWRTDVRPAPDIEGVPPAKIVYFDIEVKSDHENVFPSDRDDEVIFQIGLVLCSGTTVLRTDLLSLPGRDYDASVYQYATEGELLHAFIAYIREHEVVAVCGYNIMGFDIPYIIKRCARTSMLGTFKRIGWDSHRLAIEKTAGVGHAKMTYIQWEGVLTIDLMPIIMMDHKLDSYSLDYVANHFVKAGKDPIRPRDIFHAYNTGLMARVGRYCVKDTQLCKQLVDYLNTWVALCEMAGVCNTSIMQLFTQGQQVRVFAQIYRDCTPMDVVDKVYVIPDGGCDSDVVSPSSYTGAYVYEPVPGVYKNVIPMDFQSLYPSIIISKNICYSTLVDQGGEEYAWQEHEGCEHDPQYAKQHALGVEIGVLQCNMAALPRRATQERARMRERISEMKIQYASMTPSVVKCNVFSFRFTHAHEGVLPRVLRNLLESRARVRARIKTTDDPDIRAVLDKKQLAYKISANSVYGTMGTQRGYLPFMAGAMTTTYCGRKLIEKAAHLLKTVVGATIVYGDTDSCYIQLGHDRASLDELWQMAVNASDTVSAFFERPVRLEFEQCIYTKFIIFTKKRYVYRAFTRDGKQRTGSKGVMLSRRDSAMCARNTYAAIMSAILEGSADVPFIAVRMMHDMMIPGALQDDDFVLTKSVQDIGNGDDNNHGSYKVRNPQKAQAAATQRVAPDDAEGYAIALRQEMVKQMPAQAQLAERMRLQGRAVVSGARIEYVVLKHQYGVPEGALGARLLDFERWRDMKVAYPLDRLYYMKSVVNACDQLLVTAGYGPVCSKVYAAHLQLAYVHKQLMRRMMPTV
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: YOSB_BACSU
Sequence: MNMFVIAAKSEGKYLYGYHPHIYSNLKQAENALKTMRKNGKLTERDKVYGLDGLMLVDL
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YosB.
Protein: TROC_TREPA
Sequence: MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLLTGTKSTEILLLGAALSGLVGTVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKSPQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLLFWKELKLSTFDRDFSAVQGFSPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGVSGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG
What is the function of this protein?
Part of an ATP-driven transport system TroABCD for zinc.
What are the official names of this protein?
Zinc transport system membrane protein TroC.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YLAT1_RAT
Sequence: MVASTKYEVAAQNEADEADGSAQGDGAGPAAEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSASFGLSLVIWAVGGIFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAVIAITFANYMVQPLFPSCGAPYAAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIIAGIVRLGQGATTNFEDSFEGSSFAMGDIALALYSALFSYSGWDTLNYVTEEIRNPERNLPLSIGISMPIVTIIYLLTNVAYYSVLDIKDILASDAVAVTFADQIFGIFNWTIPLAVALSCFGGLNASIVAASRLLFVGSREGHLPDAICMIHVERFTPVPSLLFNGILALVYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSLFFPIVFCLCTIFLVAVPLYSDTINSLIGIGIALSGLPFYFLIIRVPEHKRPLCLRRIVASTTRYLQIICMSVAAEMDLEDGELPKQGPKSK
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux routeby exporting cationic amino acids from inside the cells in exchange with neutral amino acids plus sodium ions and may participate in nitric oxide synthesis via the transport of L-arginine (PubMed:10777485).  Also mediates L-arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells (By similarity).  The transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (PubMed:10777485).  In vitro, Na(+) and Li(+), but also H(+), are cotransported with the neutral amino acids (PubMed:10777485).
What are the official names of this protein?
Y+L amino acid transporter 1, Solute carrier family 7 member 7, y(+)L-type amino acid transporter 1, Y+LAT1, y+LAT-1.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein.
Protein: GLNA2_DROME
Sequence: MSARILEDSPNARINKTILDRYLSLPLQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSCYQAEGSNSDTYLYPVAIYKDPFRRGNNILVMCDTYKFDGTPTDTNKRKTCLEVANKCAAEEPWFGIEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAEVMPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAMREDGGIRDIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIPRGVNDDGKGYFEDRRPSSNCDPYSVVEAILRTICLDE
What are the official names of this protein?
Glutamine synthetase 2 cytoplasmic, Glutamate--ammonia ligase 2.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_XANOP
Sequence: MTDCSRCAGTNASGPNYWSERIRDIVDFPKPGIVFKDITPLLSDGPDFASALDEMAQPWRTTPLDAVLGIEALGFILGAALARELRTGFVPVRKPGKLPGRTLIREYALEYGTDRIEMHEGALPRGARVLIVDDVLATGGTLRAALGLAAQLELEIVGAAVLVELLALQGRQKWADDVPLLATLSF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP_PSEPO
Sequence: MIAFIVLLSLAAVLQQSSGTVDFASESSNKKNYQKEIVDKHNALRRSVKPTARNMLQMKWNSHAAQNAKRWADRCTFAHSPPNTRTVGKLRCGENIFMSSQPFPWSGVVQAWYDEIKNFVYGIGAKPPGSVIGHYTQVVWYKSHLIGCASAKCSSSKYLYVCQYCPAGNIRGSIATPYKSGPPCADCPSACVNRLCTNPCNYNNDFSNCKSLAKKSKCQTEWIKKKCPASCFCHNKII
What is the function of this protein?
Blocks olfactory (CNGA2) and retinal (CNGA1) CNG channel currents.  Is really less potent that Pseudechetoxin.  Does not affect neither depolarization- nor caffeine-induced contraction of smooth muscle.
What are the official names of this protein?
Cysteine-rich venom protein pseudecin, CRVP Pdc.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAC_CHRVO
Sequence: MKSGSGPLPRLPGSRLQQRARKQLRDGGVIAYSTESCYGLGCRPLDARAIRRVLAIKARPNHKGLIVIAADFEQIRHLVKPLSAAQRAELARYWPGPYTFLLPASRRVPPALRGRHHKIAVRVTAHGEAAALCRRLGTALVSTSANRAGQQSLKTARACRMAFKDKVLTLPGRIGKRRKPSTIIDLESGRVLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_NITEU
Sequence: MTIDYKKTLNLLDTSFPMRGDLARREPAMLKAWQERNLYRKIRAISQGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIKSKTLSGFDAPYVPGWDCHGLPIEHQIEKKYGKHLPADQVRKLCRAFAQEQIDRQKADFMRLGVLGDWEHPYLTMNYAIEAGIIRALGKIFRNGHLYQGQKPVNWCIDCGSALAEAEVEYENKRSPAIDVGFEIIGRKDVCHPLAGVMAAEIPAGTRIFAVIWTTTPWTLPANQAVCVHPEFDYSLVSTSRGWLLLASELTNACLARYQLEGRVVATCKGLALEGLSLQHPFADRIVKVICGRHVTLEAGTGLVHTAPAHGLDDYFIGQQYGLPSDSPVKGDGKFSEQISLVGGMFVWKANDVVIDTLRSSGHLLHAEEIEHSYPHCWRHKTPIIFRATPQWFIGMQRQTAESQSFGESLRDLALRAVELTRFYPAWGRARLEAMIGNRPDWCISRQRNWGVPMTFFIHKEAHTLHPRTPELLEKVAGLVEQQGIEAWFSLDATELLGEEAQHYQKLTDTLDVWFDSGTTHETVLKQNIQLRHPADLYLEGSDQHRGWFQSSLLTGCAIDGCAPYTALLTHGFVVDGQGYKMSKSKGNVIAPQKIADTLGADILRLWVASTDYSGELSISDEILKRTVETYRRIRNTLRFLLANLADFNLAADALPPAEWVEIDRYMLAYTAALQNDLLGFYERYEFHQAVARLHHFCSEDLGGFYLDILKDRLYTSMANGIPRRSAQNALYHIVHSLVRLFAPVLSFTAEEVWQELGESAEDSVFLHTWHCFPDQSEILSDAQILIPRWQRLRELRARVLKQLEDARIQGEIGSSLAAIVEIHAAGEDFALLDSLGDDLRFVLITSEVHLQRVDDAAGEVIRVTASPHMKCERCWHYRQDVGSVPEHSSLCSRCVSNLAGSGEYRRFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_HUMAN
Sequence: MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKVCALRVTSRARSRILRAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25957688, PubMed:25901680, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:25957688, PubMed:25901680, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L18, Large ribosomal subunit protein eL18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: CDA8_ARATH
Sequence: MAQPMRFMLNHIETESYGAFTPQNLSPLINRAIPHTRAQISGSPVVAVGRGSSGRTFFGVNVELPGLPLDHSIHAEQFLLANLALHFEQKLECIAISTNGYYFQEPCGHCCQLLHKIRDMSDTKILLTNPTGQKGTYMNLSTFLPQGLISQANVPRLLERNFNCIELINHSLYMDICSYSEHCNHLNCRALKAATISYAPDSKCPSGVALIDHRGKVYSGGYMESVAHNTSLGPVQAALVDFVANGDGQEFKNIVEAVLVEKKCGVLSQEATARMILEKIADPDCIFRVLHCK
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase 8.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: GRPE_SALPK
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEVEAVEPNDSAEQVDPRDEKIANLEVQLAEAQTRERDTVLRIKAEMENLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDMAAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESEEVPAGNVLGIMQKGYTLNGRTIRAAMVTVAKAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSA_BORBR
Sequence: MSIEVRGLSKRFGAFRALDEVSLHIETGELVALLGPSGCGKTTLLRIIAGLESADAGSVLFAGEDATDVDVRQRQVGFVFQHYALFKHMTVFENVAFGLRVRHRSQRPSEARIRAKVLDLLGLVQLDWLADRYPAQLSGGQRQRIALARALAVEPRVLLLDEPFGALDAKVRKELRRWLRRLHDELHVASVFVTHDQEEALEVADRVVLMNAGRIEQVGSPREVWERPATPFVYGFLGDVNQLHGHATRGVWRLGEVALPAPDLPEADNQRAIAYVRPHDIDLARAGTAAPGIPVRLNHVYLAGPSAYLELARQDDQAIIEAQVPEPLFRSLGLKEGEALLAQPRRARVFAVQP
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLMS_TROWT
Sequence: MCGIIGYSGPRPAAEVLLKGLERLEYRGYDSAGIAVVTDKAYIESVKKSGKLNVLKTCLERRTTPIVGSTGIGHTRWATHGEPSDRNAHPHMDTEQSLAIVHNGIIENSDVLKRELLASGKSFTSETDTEVVAHLLSDAFKKTQDLVQAFVEVTQRLEGAFAVVAIHKDQPNTIVAAKNNSPLLLGFGQGENFLASDIAAFAEYTQRVANIDQERIVALSGDSVYITDFAGHPVDYEVHTVSWHPASVDSSGWSSFMLKEIFEEPQAVENTLKGRTEDGTVILPECDHIRDDLLAIDRVVLVGCGTAAYAAMTASYSIEAWAGLPVSVELSHEFRYREPVLNSKTLAVFISQSGETMDSLMAVRYARQAGVKTISVCNVMDSSIPKESHAVIYTKAGPEVAVASTKSFVCQIVVLYLLALYLGQLRGFRSIFPRQKAVCELNRLPVKLKQVLEIYESVRQLAHWMSDSRSILFLGRHAGYPIALEAALKLKELAYIHAEGFAAGELKHGPIALIEPGQPVFVIVPSPVGSPILHAKVISNIREIKSRGARIIAIAAEGDSAVLPHTDSVLRIPLTRYSFEPLLSIVPLQIFALELAADKGFDVDRPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_DEHMC
Sequence: MKAVVQRVSRASVRVSGETVGEIGPGLAVLLGVAEGDTEEDAEYLASKIINLRIFSDAEGKFNLSLKDLCREMLVVSQFTLIADTRKGRRPSFIEAAQPQEADGLYNVFIRLCREEGTQVATGQFGAMMMLEIYNDGPVTIILDSRDRLNPRL
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ACIBT
Sequence: MSQTLQAAYAAKRKARRFAVQGIYEWQMSHNPVHEIEARTRAENAMHKVDLNYYHELLTQVIAQHEDLDALLIPVLDREIDALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLSSTLRSAEKQQAK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: IL25_MOUSE
Sequence: MYQAVAFLAMIVGTHTVSLRIQEGCSHLPSCCPSKEQEPPEEWLKWSSASVSPPEPLSHTHHAESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPLGNSVPLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPRVMA
What is the function of this protein?
Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production (PubMed:35615348, PubMed:11754819).  Promotes and augments T-helper type 2 responses locally or systemically (PubMed:35615348).  Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction (PubMed:18768888).  In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13.  Induces also the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways.  Inhibits the differentiation of T-helper (Th17) cells via the production of IL4, IL5 and IL13.
What are the official names of this protein?
Interleukin-25, IL-25, Interleukin-17E, IL-17E.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
Protein: NSA2_LODEL
Sequence: MPQNEYIEQHIKQHGRRLDHEERKRKKEAREGHRVAKDAQTLKGWRAKQFAKKRYSEKVSMRKKIKAHQESKVKGPSTPKQDEGEALPTYLLDRQTNNTAKALSSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKSKTKSWKRMITKHTFVGEGFTRRPVKMERIIRPAALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ERPA_ACTP2
Sequence: MSNIQIPLIFTDAAAKKVKSLIEGEDNPNLRLRVYITGGGCSGFQYGFTFDDQINEGDLTIENQNVGLVVDPMSLQYLIGGTVDYTEGLDGSRFVVQNPNASSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: UPPP_SALDC
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQREGESKGRLTLIHILLGMIPAVVLGLVFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRASGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDLYKSWSFLTAADIPMFAVGFVTAFVVALIAIKTFLQLIKRISFIPFAIYRFVVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU1M_TAMTE
Sequence: MFMINIACLIVPILLAMAFLTLVERKTLGYMQLRKGPNIVGPHGLLQPFADAVKLFTKEPLRPLTSSKLLFMVAPTLALTLALTMWAPLPMPYSLISLNLGLLFILAISSLAVYSILWSGWASNSKYALIGAIRAVAQTVSYEVTLAIILLSILLMSGSFTLTNLITTQEQMWLIIPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIMMMNALTTLLFLGAHHTPLVPEAYTANFVLKTLMLTATFLWIRASYPRFRYDQLMHLLWKNFLPITLAMLMWHVSLPMSLASIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.