PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_PSEPF
Sequence: MNKAVSDLSSHTPMMQQYWRLKNQHPDQLMFYRMGDFYEIFYEDAKKAAKLLDITLTARGQSAGQAIPMCGIPYHAAEGYLAKLVKLGESVVICEQVGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLIAAVLGDERLFGLAVLDITSGNFTVLEIKGWENLLAELERVNPVELLIPDDWPKDLPAEKRRGVRRRAPWDFERDSALKSLCQQFSTQDLKGFGCETLTLAIGAAGCLLAYAKETQRTALPHLRSLRHERLDDTVVLDGASRRNLELDTNLAGGRDNTLQSVVDRCQTAMGSRLLTRWLNRPLRDLTVLLARQTSITCLLDRYRFENLQPQLKEIGDIERILARIGLRNARPRDLARLRDALGALPELQVAMTDLEAPHLQRLATTTSTYPELAALLEKAIIDNPPAVIRDGGVLKTGYDSELDELQSLSENAGQFLIDLEAREKARTGLANLKVGYNRIHGYFIELPSKQAESAPADYIRRQTLKGAERFITPELKEFEDKALSAKSRALAREKMLYEALLEDLISQLPPLQDTAGALAELDVLSNLAERALNLDLNCPTFVSEPCMRISQGRHPVVEQVLTTPFVANDLSLDDNTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAASCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATERSLVLMDEVGRGTSTFDGLSLAWAAAERLAQLRAYTLFATHYFELTVLPEAEPLVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPSEVIVRAREHLSRLEDTALPHEAPKPAAKGKPAAPQQSDMFASLPHPVLDELAKLDLDDVTPRRALEMLYALKNRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RNH3_LACLA
Sequence: MNIVLKLETKERQQLAEKYKSYEQVSKNPYITFFAKVGKTSISVYTSGKVVFQGNEAEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDRIPHVALVVEPAKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGHKPENIVIDAFTTEANYKKYVNKEQNHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESGFTLPSGAGNLSDKIAAQIIKSQGVDALNQLAKLHFANTQKAIKIAQL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_THEPX
Sequence: MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINLIHSAENNFDAIIINPAAYTHYSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKCKGVITGFGPYSYVLALNAVKLLEDSIGG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: COF2_MOUSE
Sequence: MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGSVVVSLEGKPL
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  It is the major component of intranuclear and cytoplasmic actin rods.  Required for muscle maintenance.  May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.
What are the official names of this protein?
Cofilin-2, Cofilin, muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Note=Colocalizes with CSPR3 in the Z line of sarcomeres.
Protein: RS7_BRAHW
Sequence: MARRRRAQTRKIDADPVYGSVVISKFINKLMYDGKKSKAENIFYKAMDLVKEKTGKDGLEAFNEAIENIKPRVEVKSRRVGGSTYQVPVDVRPDRQNSLAFTWLIDASRKRGGRSMIERLSNEIVDAIDGKGQAVAKRDTVHRMAEGNKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ZPR1_PAPAN
Sequence: MAASGAVEPGPPGAAVAPSPALAPPPAPDHLFRPISAEDEEQQPTEIESLCMNCYCNGMTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRVQDQGVRYTLTVRAPEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLITRAISGLEQDQPARRANKDATAERIDEFIVKLKELKQVASPFTLIIDDPSGNSFVENPHAPQKDDSLVITHYNRTQHQKEMLGLQEEAPAEKPEEEDLRNEVLQFNTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPCQKERLQEFSQKMDQIIEGNMKAHFIMDDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLASQR
What is the function of this protein?
Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus.  Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies.  Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons.  Plays a role in the splicing of cellular pre-mRNAs.  May be involved in H(2)O(2)-induced neuronal cell death (By similarity).
What are the official names of this protein?
Zinc finger protein ZPR1, Zinc finger protein 259.
What is the protein family that this protein belongs to?
Belongs to the ZPR1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleolus. Cytoplasm, perinuclear region. Nucleus, gem. Nucleus, Cajal body. Cell projection, axon. Cell projection, growth cone. Note=Localized predominantly in the cytoplasm in serum-starved cells growth arrested in G0 of the mitotic cell cycle. Localized both in the nucleus and cytoplasm at the G1 phase of the mitotic cell cycle. Accumulates in the subnuclear bodies during progression into the S phase of the mitotic cell cycle. Diffusely localized throughout the cell during mitosis. Colocalized with NPAT and SMN1 in nuclear bodies including gems (Gemini of coiled bodies) and Cajal bodies in a cell cycle-dependent manner. Colocalized with EGFR in the cytoplasm of quiescent cells. Translocates from the cytoplasm to the nucleus in a epidermal growth factor (EGF)-dependent manner. Translocates together with EEF1A1 from the cytoplasm to the nucleolus after treatment with mitogens. Colocalized with SMN1 in Gemini of coiled bodies (gems), Cajal bodies, axon and growth cones of neurons (By similarity).
Protein: RL3_AMOA5
Sequence: MLGIIGKKLGMTTLYDEAGRSVPCTVITGGPCVVTQIKNIEKDGYTAVQLGYDDKKEKNTVKPLMGHFQKAQTTPKRKLVEFKEFGKELGKEIQLGQTIQLHDIFVEGEYVDAIGLSKGKGFQGVVKRHGFSGVGGKSHGQHNRERAPGAIGACSTPSRVFKGMRMAGRTGGQRVKITNLRIMKLVPEKNILVISGSVPGAKNGYIILEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CYNS_CHRVO
Sequence: MQSQCQPAPRQALTDAVIAAKARKRLSFEDINQGTGLSLAYTTAALLGQHALPEAAARLVAERLELDEDAIALLQAIPLRGSIPGGVPTDPTIYRFYEMVQIYGTTLKALVHEQFGDGIISAINFKLDIRKVEDPDGGHRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: CALM_DICDI
Sequence: MASQESLTEEQIAEFKEAFSLFDKDGDGSITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGNIDFPEFLTMMARKMQDTDTEEEIREAFKVFDKDGNGYISAAELRHVMTSLGEKLTNEEVDEMIREADLDGDGQVNYDEFVKMMIVRN
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Contractile vacuole.
Protein: DMW_XENLA
Sequence: MQNNEEPYNTGQYPSGPHGKKSPRLHKCARCRNHGYATPLKGHKRFCIWRDCQCQKCSLITERQRVIAAQVALQRQQAQEEELGIYHPIPLPIAAVIKREHGGSSSQLMLESSSTQTTSTPTSAEWIKEEEVAKPAAGLFAPPPSSEEMGMTLAAVGAADAATQTDQPGHLFNMMSAMIQQLMDMSWELQQGWI
What is the function of this protein?
Transcription factor that plays a key role in female sex determination and primary ovary development.  Acts as a sex-determining protein by antagonizing the transcriptional activity of male-determination protein dmrt1-a, acting as a dominant-negative type protein.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor DM-W, W-linked doublesex- and mab-3-related transcription factor, xDM-W.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AP1M1_SCHPO
Sequence: MASAIFVLNLKGKVIISRDYRADIPMSVVEKFLPLKSEVEEEQGFSTPCLTHEGINYIYIHHNDVYLLALSKMNSDAMEMLVFLRKMADVFIDYFKELQEESIRDNFVLVYELLDEIMDFGFPQTTETKILQEYITQTSNTVKKHAPPPIAMTNAISWRSEGIHYRKNEVFLDVIESVNLIAAADGTVIQSEILGKVRLKCYLSGMPELRLGLNDKVLFEAAGRTIKGNTVEMEDVKFHQCVRLARFENDRTISFIPPDGEFDLMSYRMSSNVRPLIWVECESIVHSGSRIEFMVKAKAQFKKRCIANNVQIIIPVPEDADSPRFQTSNGHVQYAPEQAAMVWNIKKFAGGKEFFMRAEMGLPSVKNEDIQVQKKRPVQLKFAIPYFTTSGIQVRYLKITEPKLNYHAMPWVRYVTQNGTEYSIRQ
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).
What are the official names of this protein?
AP-1 complex subunit mu-1, Clathrin assembly protein complex 1 mu-1 medium chain, Mu-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side.
Protein: TBB6_MAIZE
Sequence: MREILHIQGGQCGNQIGAKFWEVVCDEHGIDPTGRYTGNSDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPRGLSMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEEYEDEEEVQADDM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-6 chain, Beta-6-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TX72A_SCOMU
Sequence: MLVFYALLFVTVFSNTVMGATIDKPIPKPILREAIEEIEVNKRAQNHYCKEHNCPPGKHCPKVPIACVYGPCCF
What is the function of this protein?
Toxin that inhibits voltage-gated potassium channel currents in DRG neurons (IC(50)=about 570 nM).  In vivo, induces neurotoxicity shown by twitching, paralysis, and body contraction.  In vivo, insects injected with this toxin showed signs of neurotoxicity including twitching, paralysis, and body contraction.
What are the official names of this protein?
Kappa-scoloptoxin(07)-Ssm2a, Kappa-SLPTX(07)-Ssm2a, Kappa-scoloptoxin-Ssm2a, Kappa-SLPTX-Ssm2a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-07 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_PHOLR
Sequence: MTNIRKTHPLMKIINNSFIDLPTPSNISAWWNFGSLLGICLILHILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYMHVGRGLYYGSYTFTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFVVLALAAVHLLFLHETGSNNPSGIMSDSDKIPFHPYYTIKDILGALLLILVLTLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPLLHTSKQRGMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPYITIGQLASILYFTILLVLMPIASIVENNILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: USPB_VIBVU
Sequence: MINGDIILFALMVVTGVNLARYLTALRSLIYIMREAHPLLYQQVDGNGFFTTHGNVTKQVRLYHYLKSKEYHHHHDEVFTGKCDRVRELFVLSVSLTGVTLLAAFLL
What are the official names of this protein?
Universal stress protein B homolog.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WHIA_CLOAB
Sequence: MSFSSKVKSEVCRYDDYSKGEAIAVLSAVMKASGTLALEGNRKISFKIITENPAIARLIFKLLKKYFDIHTEIMMKKSNSLKKNNVYVVSITEDMGVRELLKTVGVMKNEDGIVTLSYDIPEFVVKDDESRKMYIRGAFLGGGSVSNPEKMYHLEFVTHNEDYASNLRDLINTYGLNSKVIQRKNSYVVYIKEGEQVVDLLNIIGAHSSLLELENIRIIKEMRNNINRLVNCETANLSKTVNASVRQIESIKLIEKQIGLSRLPENLREVAKLRLNYPDESLKELGKMLEPPVGKSGVNHRLRKIEKIAEELRKEGR
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: MSHA_CORDI
Sequence: MMTMRIAMISIHTSPLQQPGSGDAGGMNVYIISIARELARRGVDVDIYTRATRPSQGDVVEVESGLRVINIVAGPYEGLSKEELPTQLAAFAGGVVQFAKCHHMRYDVIHSHYWLSGQVGWLLRDLWNIPLVHTAHTLAAVKNAHRSAGDTEESEARRICEQQLVDNADILVVNTPEETNDLVRHYDANPDSVAVIAPGANVELFTPGTQRNTEQSRRCLGIPLHTKVMAFVGRLQQFKGPEVLLRAVAEMLERDPDRDMRVIMCGGPSGAAATVEHYIELTRSLGIAHRVRFLDPRPPEELVSVYQAADVVAVPSYNESFGLVAMEAQASGTPVVAARVGGLPIAVVDGETGVLVDGHDPIMWADALEQLLDDDPTRQQMGVAAVEHAANFTWAAAAEKLESVYGDAAMLDVAQCHDRYAAGSDRA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: IL8_MACMU
Sequence: MTSKLAVALLAAFLLSAALCEGAVLPRSAKELRCECIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKEPWVQRVVEKFVKRAENQNP
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNF26_MOUSE
Sequence: MEAVYLVVNGVGLVLDLLTLMLDLNFLLVSSLLATLAWLLAFIYNLPHTVLTSLLHLGRGFLLSLLALVEAVVRFTFGGLQALGTLLYSCYSGLESLKLLGHLASHGALRSREFLNRGILNMVSNGHALLRQACDICAIAMSLVAYVINSLVNICLISTQNFFSLVLALWDAVTGPLWRMTDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASCVVFHLTGLVLLACVLAVILIVLHPEQTLRLATQALSQLHARPSYHRLWEDIVRLTRLPLGLEAWRRVWSRSLQLASWPNRGGAPGAPQGGPRRVFSARIQPQDTPPEAEEEVIRTAPARGREQLNEDEPAAGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRSILQTLNVYL
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud.  Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the ubiquitin conjugating enzyme UBE2J1.  Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport.  Also acts as a regulator of type I interferon production in response to viral infection by mediating the formation of 'Lys-11'-linked polyubiquitin chains on TMEM173/STING, leading to stabilize TMEM173/STING.  Also required to limit type I interferon response by promoting autophagic degradation of IRF3.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF26, RING finger protein 26.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PLY2_AMBAR
Sequence: MGIKQCCYILYFTLALVALLQPVRSAEGVGEILPSVNETRSLQACEALNIIDKCWRGKADWENNRQALADCAQGFAKGTYGGKWGDVYTVTSNLDDDVANPKEGTLRFAAAQNRPLWIIFKNDMVINLNQELVVNSDKTIDGRGVKVEIINGGLTLMNVKNIIIHNINIHDVKVLPGGMIKSNDGPPILRQASDGDTINVAGSSQIWIDHCSLSKSFDGLVDVTLGSTHVTISNCKFTQQSKAILLGADDTHVQDKGMLATVAFNMFTDNVDQRMPRCRFGFFQVVNNNYDRWGTYAIGGSSAPTILCQGNRFLAPDDQIKKNVLARTGTGAAESMAWNWRSDKDLLENGAIFVTSGSDPVLTPVQSAGMIPAEPGEAAIKLTSSAGVFSCHPGAPC
What is the function of this protein?
Has pectate lyase activity.
What are the official names of this protein?
Pectate lyase 2, Antigen Amb a I, Antigen E, AgE, Pollen allergen Amb a 1.3.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. Amb a subfamily.
Protein: METK_FUSNN
Sequence: MKKFTYFTSEFVSPGHPDKISDQISDAILDACLKDDPNSRVACEVFCTTGLVVVGGEITTSTYIDVQDIVRKKIDEIGYRPGMGFDSNCGTLSCIHAQSPDIAMGVDIGGAGDQGIMFGGAVRETEELMPLALVLSREILVKLTNMMKSNEIEWARPDQKSQVTLAYDENGKVDHVDSIVVSVQHDEDTTHDEIEKIVIEKVVKPVLEKYNLSSDNIKYYINPTGRFVIGGPHGDTGVTGRKIIVDTYGGYFKHGGGAFSGKDPSKVDRSAAYAARWVAKNIVAAELADKCEIQLSYAIGVPKPVSVKVDTFGTSKVDEDKISEAVSKVFDLSPRGIEKALELREGNFKYQDLAAFGHIGRTDIDTPWERLNKVDELKKAIEL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBOX3_RAT
Sequence: MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGAQLQVHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE
What is the function of this protein?
Binds to the GM-CSF promoter.  Seems to act as a repressor.  Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'.  May have a role in translation repression (By similarity).
What are the official names of this protein?
Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Muscle Y-box protein YB2, RYB-A, Y-box-binding protein A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ANIS1_ANISI
Sequence: MASMQHFSLAALLLAASICLGDADRTECQLPLDKGTPCTQEGGVKPSVAWWHDDKSGICLSFKYTGCGGNANRFTTIKNCEQHCKMPDRGACALGKKPAEDSNGEQLVCAGMREDKCPNGYQCKMMAFMGLCCPTKEEELFAREYEGVCKSGKPVKMDRGSGWMMTILGKSCDDQFCPEDAKCERGKLFANCCK
What are the official names of this protein?
Major allergen Ani s 1, 21 kDa allergen, Excretory gland allergen Ans1.
What are the subcellular locations of this protein?
Secreted.
Protein: RHOAC_DANRE
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRINAFGYLECSAKTKDGVREVFEMATRAALQARKRGKKSGCLLL
What is the function of this protein?
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
What are the official names of this protein?
Rho-related GTP-binding protein RhoA-C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MYHV1_BOMMX
Sequence: MNFKYIVAVSFLIASGYARSEENDVQSLSQREVLEEESLREIRGIGGALLSAGKSALKGLAKGFAEHFGKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLSLVGSALGGLIKKIG
What is the function of this protein?
Maximin-Hv shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins y/Hv type 1.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLUC_LAMFL
Sequence: HSQGSFTSDYSKYLDSKQAKDFVIWLMNT
What is the function of this protein?
Glucagon plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_CATGU
Sequence: MALNLRKNHPLLKTINDALIDLPTPSNISTWWNFGSLLGICLVTQIVTGLLLAMHYTADTSLAFNSVAHMCRNVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKETWNIGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPADCDKIPFHPYYSTKDILGFALMLILLISLALFSPNMLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLFPLLHKSKQRSMTFRPLSQILFWTLVANLLVLTWVGSQPVEHPFIIIGQLASISYFTIILVLFPLAAVLENKMLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: U729_DROSI
Sequence: MVCVPCFIIPLLLYIWHKFVQPIILRYWNPWEKKDAQGNVIKKGPDFPFECKGGVCPFVPGAKKPEKASVGPAEESQNPPLNAIAAETEVDESKKEI
What are the official names of this protein?
UPF0729 protein GD16342.
What is the protein family that this protein belongs to?
Belongs to the UPF0729 family.