PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_ACIB3
Sequence: MKISLSLQQDFRSPELELKRAQLKKIIETTLRHVGYKEDCEIGIACVDLEESHQLNLQYREKDKPTNVLSFPSDIPEEVLPMLDALPLGDLVICIPVVLQEALEQKKTAQNHFAHLLVHGVLHLLGYDHETSDEDAEEMEGLEIEILAKLNIANPYQE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ESCF3
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAAASGRLLAGSGANISIDKRLPMGGGLGGGSSNAATVLVALNNLWQCGLSMDELAELGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: IPYR_UREPA
Sequence: MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLVFADQAFQPGIKVPARVLGAMKMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLHWLAEVQDFFENYKNLQNKKVKILGFEDEIWAQKEYEECVLLMKEYGHLKKDEFVTKMMKERPEKYIK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8862_DICDI
Sequence: MDSLSNYSNSLSSSGEISNKFAKIGSSILYGYYDYLTATSRVLHGEDKIKNTK
What are the official names of this protein?
Uncharacterized protein DDB_G0272514.
Protein: CNPD3_RHOE4
Sequence: MSVRSAEYPRPKHFLVHLSDTHLVAQGELYDAVDASTRLREVLSGIVASGARPDALIFTGDLTDQGHPDAYAELKAIVEPVAAEIDAQVIWAMGNHDDRSTFRSLLLGEDATDHPVDNVYDLDGLRVITLDSSVPGHHYGEISDRQLDWLRSELAVPAPDGTILALHHPPVPCIQDLAVLVELRDQSRLADVLRGSDVRAILAGHLHYSTTATFAGIPVSVASSTCYTQDLNVEVGGQRGRDGAQGCNLVHVYDETIVHSVVPLGAHVTVGEPVDADEGARRLSAAGIRILESEKAGRSIV
What are the official names of this protein?
Probable cyclic nucleotide phosphodiesterase RER_40650.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: TRHO_PSEPF
Sequence: MTQPIVVAALYKFVTLEDYVNLREPLLQAMVDNGIKGTLLIAEEGINGTVSGSREGIDGLLAWLRNDPRMVDIDHKESYCDEQPFYRTKVKLKKEIVTLGVEGVDPNKKVGTYVEPKDWNALISDPEVLLIDTRNDYEVSIGTFEGAIDPKTTSFREFPDYIKEHFDPAVHKKVAMFCTGGIRCEKASSYMLGEGFEEVYHLKGGILKYLEEVPQEETKWQGDCFVFDNRVTVRHDLSEGDYDQCHACRTPVSVEDRASEHYVAGISCPHCWDTLSEKTRRSAIDRQKQIELAKARNMPHPIGYNYKQASTEA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: XY11B_CELJA
Sequence: MKIFQNTKNVIVSIAWAAALCTSAVSAQTLTSNSTGTNNGFYYTFWKDSGDASMTLLSGGRYQSSWNSSTNNWVGGKGWNPGSSSRVISYSGYYGVDSSQNSYLALYGWTRSPLIEYYVIESYGSYNPASCSGGTDYGSFQSDGATYNVRRCQRVNQPSIDGNQTFYQYFSVRNPKKGFGNISGTITFANHANFWATKGLNLGNHNYQVLATEGYQSRGSSDITVSQGGSSGGGNSSSSSSASGGGSKIIVVRARGTAGGESITLRVGNTNVATWTLTTTMTNYTATTSASGGSLVQYTNDSGNRDVQVDYISVNGSIRQSEDQTYNTGVYQNGSCGGGNGRSEWLHCNGAIGYGDI
What is the function of this protein?
Endo-acting xylanase which specifically cleaves internal linkages on the xylan backbone, releasing xylooligosaccharides.  Is able to hydrolyze glucuronoxylan and the arabinoxylan from wheat.
What are the official names of this protein?
Endo-1,4-beta-xylanase Xyn11B, Xylanase 11B, 1,4-beta-D-xylan xylanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_RALSO
Sequence: MSHFPKLLSSQIAFDVARTMLDGFDKHYRLFREVSVRAKALFEAGDWQGLQQLQRDRIAYYDERVREASVILEDEYDAENIDDEIWRQIKLHFIGLLTNHHQPECAETFFNSVCTRILHRSYFNNDFIFLRPAISTEYIENEESPTKPTYRAYYPGSREGLGGCLERIVHNFQLDAPFEDLPRDIGYVVRAVGEHFGDFRIAPNFQIHVLSSLFFRNTAAYIIGRVINGDKTYPLAVPIMRGADGQLRLDTVLLRPEQLLILFSFTHSYFMVDMEIPSAYVTFLRDLMPRKPRAEIYTSLGLQKQGKNLFYRDFLHHLQHSSDKFIIAPGIKGLVMLVFTLPSYPYVFKVIKDYFPPPKETTRELIKSKYQLVKQHDRVGRMADTLEYSDVAFPLSRFDDALIKELEKHAPSMVEYQRGADGSDEIVIRHVYIERRMTPLNIWLHEGTDAQVEHGIIEYGNAIKELIAANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRDVPQPRNEEEEMSGEVWYSVGPHDIFPQTYGTFLLGDPRVREAFLRHHADFFDPAMWQAHKARLLSGQTHDFYAYDASERFVNRYGDSAPGNAATPLRRAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CYACA
Sequence: MKKNQFANKLIVIDLLSVQRESFYSFLTEGLAKELNNFSPIIDYTGKLELHLVTNQLVIKKPKFSFEEAKRRDCSYTISINIVTQLFNKNSGDVKEQEILLGEIPLMTQKGTFVINGAERVIVNQIVRSPGIYFNSEMDKNNLKTFNFLIIPNRGAWLKCEIDKNDLIWIRIDKNKKINLSIFFKALGIDHDDLRIKNAFRQPEFIYKNLNKDENYTQQEALEELHKKLFPGEPATSEASTKILYFKFFNPKKYDLGIVGRKKINKKLDLNSPENIRILTIQDILSGINYLINLKFGFGNIDDIDHLANRRLKSVGELLQSQISIGLIRLERLIKERMTICEQSSLVPSALINPKPIFAAIKEFFNSSQLSQFMDQVNPLAELTHKRRVSSLGPGGLSKERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLAIYARINPDGFIEAPFYKVNQGQVLKNKGIIYLDAEQEDEFKIAPGDIRINETNFIKEINVPVRYRQEFTQCPAEEIDFIAVSPIQVISAATSLIPFLEHNDANRALMGSNMQRQAVPLIFPERPLVGTGLEAQIAKDSGIMAISRSNGIVKFTSAEKIIVTDSSNNQITYNLQKYQKSNQETCINHRPIVWPGERIKKGQILADGSATDTGELALGRDVLVAYMPWEGYNYEDAFLISDRLVYEDLYTSIHIEKYEIEARQTKLGPEEITRNIPNVGENSLKQLDENGIVVVSSFVESGSILVGKVTPKGESDQPPESKLLQAIFGEKNKDVKDTSLRLPNGTRGRVVDVRIFSREKGDELAVGINYIVRIYVAQKRKIQIGDKMAGRHGNKGIISKILPRQDMPYLPNGTPVDIILNPLGVPSRMNVGQIFECILGISAFNLKKRFRILPFDEMYESDSSRILINQKLKEAQTLTNLDYLFNENHLGKVALFDGRSGEKFDNPVLVGKIYMMKLVHLVDDKIHSRSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWAFEAFGAAYALQELLTIKSDDIQGRNEALTAIVRGKTIPKPGTPESLKVLMREIQSLGLDIAAYRLPNLHHGEIKSIEIDLTHNKIVQKR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SVOP_BOVIN
Sequence: MEEDLFQLRQLPVVKFRRTGESARSEDDTASGEHEVQIEGVRAGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVVFSFCSLLLFICVGRNMLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGAHGTGVARSNSGSQE
What are the official names of this protein?
Synaptic vesicle 2-related protein, SV2-related protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: RL23_NAUPA
Sequence: MADITDIKSIVYTEKALNLQEQGVLVVQTTPKVTKNQLKEIFKEYFGVTPLKVNSLRQKGKVKRFRGIEGKRPDYKKFYVKLPEDAKLESLSV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MCH2_ONCMY
Sequence: MRDSVLSVIFALALFLECYTPSMAIPMGKMEDTALEQDTLDSLLNEEVADKNPDSVRSGSSKIIVLADSGMWKNLNRGLPLYKLKAAAAGLDRALTLDRREADQDLSPSISIVRRDTMRCMVGRVYRPCWEV
What is the function of this protein?
Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha.  Induces melanin concentration within the melanophores.  May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.
What are the official names of this protein?
Pro-MCH 2.
What is the protein family that this protein belongs to?
Belongs to the melanin-concentrating hormone family.
Protein: Y3422_BRUAB
Sequence: MKRRTFLAMSLALTFLPSVALADNIPVRVGYIADYWGTSITAIASEKGLWEKHGLDADTRVFTNGPIQVQALGAGSLDFGYIGPGALWLPASGKAKIVAINSVGFSDRVIAQEGFKSMADLKGKKIGVPEGTSGDMLLRLALGKAGMKLDDVQVIKMDPSTVVSAFASKQIDAAGIWYPLIGTIKEHVPGMVELAANSDFFPDKTFPSAFIARNEIVAENPEAVKRMIAVIEEAEDFRTANPEQSVDITAKFLKVDKANLETEAKNGKSLTSEELVKLTRDGSVNGWLSGMADMFVTFGKLKSPLDPKDYYLADYFTAK
What is the function of this protein?
Probably part of an ABC transporter complex.
What are the official names of this protein?
Putative binding protein BruAb2_1122.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein SsuA/TauA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MFN2_MOUSE
Sequence: MSLLFSRCNSIVTVKKDKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESASFLEDTHRNTELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIRRLSVLVDEYQMDFHPSPVVLKVYKNELHRHIEEGLGRNLSDRCSTAIASSLQTMQQDMIDGLKPLLPVSMRNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMPPLPQSSLTQEELMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQELSGTFAHLCQQVDITRDNLEQEIAAMNKKVEALDSLQSRAKLLRNKAGWLDSELNMFTHQYLQPSR
What is the function of this protein?
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:23620051).  Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events.  Overexpression induces the formation of mitochondrial networks.  Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity).  Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes.  Plays an important role in the regulation of vascular smooth muscle cell proliferation (By similarity).  Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy).  Is required for PRKN recruitment to dysfunctional mitochondria (PubMed:23620051).  Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (PubMed:23921556).  Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (PubMed:23921556).
What are the official names of this protein?
Mitofusin-2, Hypertension-related protein 1, Mitochondrial assembly regulatory factor, HSG protein, Transmembrane GTPase MFN2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=Colocalizes with BAX during apoptosis.
Protein: CH60_TRYBB
Sequence: MFRCVVRFGAKDIRFGTEARQSMLKGVQRAVEAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKSIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASIFSEGIKSIATGTNPIDMKRGMDRAVEVILKNIESQSRTVTNTENVVQVATISANGDVELGKLIGEAMEKVGKDGVITTQDGKTLTTELEVVEGMSVDRGYISPYFVTDAKTQKAELEDAFVLVSAKKLNNIHTILPVLNHVVRSGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKAAMLQDIAIFSGACVVGEEGSGVELDAEKFEASILGSVKKATITKDDTVLLNGGGDVAMMKERVDLVRGLIERETSDYNREKLQERLAKLSGGVAVIRVGGASEVEVNEKKDRITDALCSTRAAVQEGIVPGGGPALLRASKALDGLLQDQSLTADQRTGVQIIRNAVRLPAHRIVANAGREGAVVVEKVLENTDAAVGYDAQLDRYVNMFEAGIIDPARVVRVALTDAASVASLMMTAEAAVVDLPKDDAPAAGGMGGMGGMGGMDGMY
What is the function of this protein?
Implicated in mitochondrial protein import and macromolecular assembly.  May facilitate the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
What are the official names of this protein?
Chaperonin HSP60, mitochondrial, Protein Cpn60, Heat shock protein 60, groEL protein.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y1390_ARATH
Sequence: MSFEEEEEEETFEHTLLVVREVSVYKIPPRTTSGGYKCGEWLQSDKIWSGRLRVVSCKDRCEIRLEDSNSGDLFAACFVDPGRRENSVEPSLDSSRYFVLRIDDGRGKYAFIGLGFAERNEAFDFNVALSDHEKYVRREKEKETGETSESDNHIDIHPAVNHRLKEGETIRINVKPKPTTNGTGMLSAALSGTGKPKPLALAPPPKAAGVTRSPLPPPPNDPVASRIASDGCKESRRNEPLSDLSQLKKNLPSTAGSGSSKSTGAASGWAAF
What are the official names of this protein?
Uncharacterized protein At1g03900.
Protein: FLIW_CLOBJ
Sequence: MKLNTKYHGCIEYEEKDVIYFQKGIPGFEELNKFIIFPVEDNEVFLVFHSIENEDIGIIVTSPFNIENNYEIQLEEEQITNLKLQDEKDALVLNTVTLDSDIDKITVNLRAPIIINIKEKIGEQIIINSDKYKVKHSLFKEEA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_ENT38
Sequence: MQILLANPRGFCAGVDRAISIVENALEIYGAPIYVRHEVVHNRYVVESLRERGAIFIEQISEVPDGTILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPEDVLTLNVKNDAKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVLVVGSKNSSNSNRLAELAQRMGKTAFLIDDATDIQEAWVKDVNCVGVTAGASAPDILVQNVIARLQELGGGDAIPLEGREENIVFEVPKELRIDAREVE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL24B_SCHPO
Sequence: MKVEVCSFSGSKVYPGAGRLFVRGDNKVFRFVNKKSESLFLQRKNPRRLSWTVLYRRMHKKGISEEHAKKRTRRTVKHQRGIVGANLDVIKEKRNQRPEVRAAARAAALKQRKDKRAASESEKKAIKAKSAASSARGQAIKNAKVAARR
What are the official names of this protein?
60S ribosomal protein L24-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: DBP10_YEAS7
Sequence: MAGVQKRKRDLEDQDDNGSEEDDIAFDIANEIALNDSESDANDSDSEVEADYGPNDVQDVIEYSSDEEEGVNNKKKAENKDIKKKKNSKKEIAAFPMLEMSDDENNASGKTQTGDDEDDVNEYFSTNNLEKTKHKKGSFPSFGLSKIVLNNIKRKGFRQPTPIQRKTIPLILQSRDIVGMARTGSGKTAAFILPMVEKLKSHSGKIGARAVILSPSRELAMQTFNVFKDFARGTELRSVLLTGGDSLEEQFGMMMTNPDVIIATPGRFLHLKVEMNLDLKSVEYVVFDEADRLFEMGFQEQLNELLASLPTTRQTLLFSATLPNSLVDFVKAGLVNPVLVRLDAETKVSENLEMLFLSSKNADREANLLYILQEIIKIPLATSEQLQKLQNSNNEADSDSDDENDRQKKRRNFKKEKFRKQKMPAANELPSEKATILFVPTRHHVEYISQLLRDCGYLISYIYGTLDQHARKRQLYNFRAGLTSILVVTDVAARGVDIPMLANVINYTLPGSSKIFVHRVGRTARAGNKGWAYSIVAENELPYLLDLELFLGEKILLTPMYDSLVDVMKKRWIDEGKPEYQFQPPKLSYTKRLVLGSCPRLDVEGLGDLYKNLMSSNFDLQLAKKTAMKAEKLYYRTRTSASPESLKRSKEIISSGWDAQNAFFGKNEEKEKLDFLAKLQNRRNKETVFEFTRNPDDEMAVFMKRRRKQLAPIQRKATERRELLEKERMAGLSHSIEDEILKGDDGETGYTVSEDALKEFEDADQLLEAQENENKKKKKPKSFKDPTFFLSHYAPAGEIQDKQLQITNGFANDAAQAAYDLNSDDKVQVHKQTATVKWDKKRKKYVNTQGIDNKKYIIGESGQKIAASFRSGRFDDWSKARNLKPLKVGSRETSIPSNLLEDPSQGPAANGRTVRGKFKHKQMKAPKMPDKHRDNYYSQKKKVEKALQSGISVKGYNNAPGLRSELKSTEQIRKDRIIAEKKRAKNARPSKKRKF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10, DEAD box protein 10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HGL2_ARATH
Sequence: MSMAVDMSSKQPTKDFFSSPALSLSLAGIFRNASSGSTNPEEDFLGRRVVDDEDRTVEMSSENSGPTRSRSEEDLEGEDHDDEEEEEEDGAAGNKGTNKRKRKKYHRHTTDQIRHMEALFKETPHPDEKQRQQLSKQLGLAPRQVKFWFQNRRTQIKAIQERHENSLLKAELEKLREENKAMRESFSKANSSCPNCGGGPDDLHLENSKLKAELDKLRAALGRTPYPLQASCSDDQEHRLGSLDFYTGVFALEKSRIAEISNRATLELQKMATSGEPMWLRSVETGREILNYDEYLKEFPQAQASSFPGRKTIEASRDAGIVFMDAHKLAQSFMDVGQWKETFACLISKAATVDVIRQGEGPSRIDGAIQLMFGEMQLLTPVVPTREVYFVRSCRQLSPEKWAIVDVSVSVEDSNTEKEASLLKCRKLPSGCIIEDTSNGHSKVTWVEHLDVSASTVQPLFRSLVNTGLAFGARHWVATLQLHCERLVFFMATNVPTKDSLGVTTLAGRKSVLKMAQRMTQSFYRAIAASSYHQWTKITTKTGQDMRVSSRKNLHDPGEPTGVIVCASSSLWLPVSPALLFDFFRDEARRHEWDALSNGAHVQSIANLSKGQDRGNSVAIQTVKSREKSIWVLQDSSTNSYESVVVYAPVDINTTQLVLAGHDPSNIQILPSGFSIIPDGVESRPLVITSTQDDRNSQGGSLLTLALQTLINPSPAAKLNMESVESVTNLVSVTLHNIKRSLQIEDC
What is the function of this protein?
Transcription factor involved in the determination of epidermal cell identity (Probable).  Required for correct morphological development and maturation of trichomes (PubMed:7926739).  Regulates the frequency of trichome initiation and determines trichome spacing (PubMed:11844112).  Acts as a negative factor for root hair development (PubMed:8620852, PubMed:8811855, PubMed:26486447).  Required for ectopic repression of root hair development in a subset of epidermal cells (PubMed:8811855).  May suppress hair formation in root epidermis by promoting differentiation into hairless epidermal cells (PubMed:8620852).  Directly suppresses the bHLH transcription factor genes, RHD6, RSL1, RSL2, LRL1, and LRL2, which have diverse functions in root hair development (PubMed:26486447).  Required for normal development of seed coat mucilage (PubMed:7926739, PubMed:21883555).  Involved in the control of seed oil accumulation (PubMed:16514561, PubMed:21883555).  Acts as a negative regulator of anthocyanin biosynthesis (PubMed:26017690).  May directly repress the expression of some component genes from the MYB-bHLH-WD40 (MBW) transcriptional activator complex (PubMed:26017690).  The MBW complex activates the transcription of late biosynthesis genes in the flavonoid pathway, leading to the production of anthocyanins (Probable).
What are the official names of this protein?
Homeobox-leucine zipper protein GLABRA 2, Protein GLABRA2, HD-ZIP protein ATHB-10, Homeobox-leucine zipper protein ATHB-10.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR2_PINKO
Sequence: MSKRYWNIDLEEMMEARVHLGHKTRKWNPKMAPYIFTERKDTHIINLAKTARSLSEACDLVFDIAGRGKQFLIVGTKYQATDLVASAATEARCHYVNRKWLGGMLTNWSTTETRLQKFKDLKKEQDTGRFNQLPKKEAAMLKRQLDQLQKYLGGIRYMRSLPDIAIITNQREESIALGECRTLGIPTICLVDTDCDPDLVDIPIPANDDGIASIQLILNRLTSAICEGRALRSL
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_FRASN
Sequence: MAASRSASRISFAKIIEPLEVPDLLALQTQSFDWLIGNDIWAERVQEAIDADRNDVPITSGLEEVFEEISPIEDFSGSMSLSFRDHRFEPPKYSVEECKDKDMTYSAPLFVTAEFTNNTTGEIKSQTVFMGDFPLMTPKGTFVINGTERVVVSQLVRSPGVYFEKAIDKASDKDLFSCKVIPSRGAWLEFEIDKRDTVGVRIDRKRRQSVTVLLKALGWDEARILERFGDFPSMRVTLEKDHTSSQDDALLDIYRKLRPGEPPTRESAQTLLENLFFNPKRYDLAKVGRYKVNKKLTLEVAHDVGVLTEDDVVRTIEYIVKLHAGQDPDNYEVDDIDHFGNRRLRTVGELIQNQVRLGLARMERVVRERMTTQDVEAITPQTLINIRPVVASIKEFFGTSQLSQFMDQTNPLAGLTHKRRLSALGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSTFARVNPFGFVETPYRKVENGRVTGQIDYLTADEEDRHVKAQANTPLNADGTFAEDRVLVRRKGGEVEFIPPDEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGSNMQRQSVPLLRSEAPLVGTGMEARAAKDAGDVVVCAQSGVVEDLSADYITVMHDDGTRRTYRLAKFRRSNQGTCINQKPIVFEGDRVEAGQVIADGPCTDNGEMALGKNLLVAFMPWEGHNYEDAIILSQRLVQDDVLSSIHIEEHEVDARDTKLGPEEITRDIPNVAEEVLADLDERGIIRIGAEVSPGDVLVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGVRVFSREDGDELPPGVNELVRVYVAQKRKITDGDKLAGRHGNKGVIAKILPVEDMPFLPDGTAVDVVLNPHGVPRRMNIGQILETHLGWVAKTGWQVDSGAEGWKERLRGIGADAAPPGTNVATPVFDGAREEEITGLLDATLPNRDGQQMIGSSGKAELYDGRTGEPYPYPVAVGYIYILKLLHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYALQELLTIKSDDVVGRVKVYEAIVKGENIPEPGIPESFKVLIKEMQSLCLNVEVLSSDGVSIEMRDTDEDVFRAAEELGIDLSRREPSSVEEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CDC6_DESA1
Sequence: MADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNVLIYGLTGTGKTVVVKYVVSKLKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRVPHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREGDDLIYKLVRANEELSKAKIVLIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVISYCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLPLHQKLVLKKIVELVEAKESTTTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLIISEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: AZIN1_HUMAN
Sequence: MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHTLTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKNCRHLLECAKELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIGFTMNMLDIGGGFTGTEFQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEKTGSDEPAFMYYMNDGVYGSFASKLSEDLNTIPEVHKKYKEDEPLFTSSLWGPSCDELDQIVESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQEDSFSAEA
What is the function of this protein?
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake.  AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948).  Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).
What are the official names of this protein?
Antizyme inhibitor 1, AZI, AZI1, Ornithine decarboxylase antizyme inhibitor.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC antizyme inhibitor subfamily.
What are the subcellular locations of this protein?
Nucleus.