PharMolix/UniProtQA huggingface dataset:
Protein: VP2_ROTRF
Sequence: MAYRKRGARREANINNNDRMQEKDDEKQDQNNRMQLSDKVLSKKEEVVTDSQEEIKIADEVKKSTKEESKQLLEVLKTKEEHQKEIQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKLFRIFEPRQLPIYRANGEKELRNRWYWKLKKDTLPDGDYDVREYFLNLYDQVLTEMPDYLLLKDMAVENKNSRDAGKVVDSETASICDAIFQDEETEGAVRRFIAEMRQRVQADRNVVNYPSILHPIDYAFNEYFLQHQLVEPLNNDIIFNYIPERIRNDVNYILNMDRNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKELVSTEAQIQKMSQDLQLEALTIQSETQFLTGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVVPNDMFIRESLVACQLAIVNTIIYPAFGMQRMHYRNGDPQRPFQIAEQQIQNFQVANWLHFVNNNQFRQVVIDGVLNQVLNDNIRNGHVINQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLAYNYETLMACVTMNMQHVQTLTTEKLQLTSVTSLCMLIGNATVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITGANRLNLYQKKMKAIVEDFLKRLHIFDVARVPDDQMYRLRDRLRLLPVEVRRLDIFNLILMNMDQIERASDKIAQGVIIAYRDMQLERDEMYGYVNIARNLDGFQQINLEELMRTGDYAQITNMLLNNQPVALVGALPFVTDSSVISLIANVDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWVPTSTTKVYKQVPQQFDFRNSMHMLTSNLTFTVYSDLLAFVSADTVEPINAVAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: SFSA_THEM4
Sequence: MMNIIKIDNTQSGIFLERINKYLAKIYLNENVVDVHVHDPGRLKELLFKNNKVLVKKVNSTNRKTKYDLIAAKKEKEYVLVHSMYHRYIAEKILRKKYTHLKAEVKYKNSRIDFLAEDKFWIEIKGCTLSDGNMARFPDAPTKRGTKHLEDLMELKKQGFDTFIYFLIFANANYFSPNYETDLSFSKKLEEAYSLGVKIVPLLFSLENNWIVFKREIQLIFDG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: FABZ_ALKOO
Sequence: MNLNSIEIQKIIPHRYPFLLVDKIIDMEVGKRAVGIKNVTINEPFFQGHFPDQPIMPGVLIVEAMAQVAAVICMGSEENEGKLGVFTGIDNCKFRKQVVPGDALHIEIEMTAFRRGIGKAEGKAYVDGQLACSASLTFALIDKA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_XYLFA
Sequence: MTTNDSWFTEHFQATGSAIGFRITGKLDEVQSPFQKIEIYNSTDWGKLMVIDGALMLTSRDNFLYHEMISHPALFTHTAPKCVVIIGGGDCGTLREVLKHPDIEQVTQCDIDEQVTRMAEKHFPELCTSNNDPRATLLFSDGVAYMTDCPTNSVDVIIVDSTDPVGPAKGLFNRTFYESCFRALKNDGLLVQQSESPLALLELIKEMRHEMSKAGFKAFKTLPFPQPCYPTGWWSVTLSSKQPNANFAFRQTDAQTKPFDTLYYNAHLHHGVLVPPPFIAHALGE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SYNSC
Sequence: MNKTSLPPIDSIDRQWYVVDAENQTLGRLATEVAAVLRGKTNPSFTPHLDTGDFVVVVNAEKIKVSGRKPQQKLYRRHSGRPGGMKVETFEALQERIPERIVEKAIKGMLPHNALGRQMFRKLKVYKGTEHPHAAQKPQPLQLNPSASAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GDO_TRIMO
Sequence: ARQLNPSDQELQSPQQLYPQQPYPQQPY
What are the official names of this protein?
Omega-gliadin.
Protein: RECR_PROMS
Sequence: MITYTKPLSKLIGHFEKFPGIGPRTAQRLALFILKQPESTIRDFSKALLEAHNNVGRCKKCFNLTSEDECEICRNTERNQKLICVVSETKDLLALERAREFKGVYHVIGGLISPMDSVGPELLEIRSLVERVSKSEIDEIILALTPSVEGDTTSLYIGKLLSPFTKVTRIAYGLPMGSELEYVDEVTLARALEGRTKLN
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ASSY_PROMS
Sequence: MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASKSIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPVEIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGMVEKKWGQLVYQGFWFGPLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNSKTKD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLK6_ARATH
Sequence: MEYHPQAIRLCALIFISFYALLHLVEAQDQKGFISLDCGSLPNEPPYNDPSTGLTYSTDDGFVQSGKTGRIQKAFESIFSKPSLKLRYFPDGFRNCYTLNVTQDTNYLIKAVFVYGNYDGLNNPPSFDLYLGPNLWVTVDMNGRTNGTIQEIIHKTISKSLQVCLVKTGTSSPMINTLELRPLKNNTYNTQSGSLKYFFRYYFSGSGQNIRYPDDVNDRKWYPFFDAKEWTELTTNLNINSSNGYAPPEVVMASASTPISTFGTWNFSWLLPSSTTQFYVYMHFAEIQTLRSLDTREFKVTLNGKLAYERYSPKTLATETIFYSTPQQCEDGTCLLELTKTPKSTLPPLMNALEVFTVIDFPQMETNPDDVAAIKSIQSTYGLSKISWQGDPCVPKQFLWEGLNCNNLDNSTPPIVTSLNLSSSHLTGIIAQGIQNLTHLQELDLSNNNLTGGIPEFLADIKSLLVINLSGNNFNGSIPQILLQKKGLKLILEGNANLICPDGLCVNKAGNGGAKKMNVVIPIVASVAFVVVLGSALAFFFIFKKKKTSNSQDLGPSSYTQVSEVRTIRSSESAIMTKNRRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNTEQVAVKMLSHSSSQGYKEFKAEVELLLRVHHKNLVGLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHVSTVVAGTPGYLDPEYYRTNWLNEKSDVYSFGIVLLEIITNQLVINQSREKPHIAEWVGLMLTKGDIQNIMDPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQVVIELNECLSYENARGGTSQNMNSESSIEVSMNFDIGATPDAR
What is the function of this protein?
Probable receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates.
What are the official names of this protein?
Receptor-like protein kinase At3g21340, Leucine-rich repeat receptor-like protein kinase At3g21340.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CATR_ATRNU
Sequence: MSSARTVRKDKPRGRHHGLTQQKRQEIKEAFELFDTDGSGTIDAKELNVAMRALGFEMTEEQINQMIADVDKDGSGAIDFDEFCHMMTAKIGERDTKEELMKAFRIIDQDNNGKISPEDIQRIAKELGENFTVKDIQDMIEEADRDRDGEVNVEEFLRMMKRTSYAY
What is the function of this protein?
Plays a fundamental role in microtubule-organizing center structure and function.
What are the official names of this protein?
Caltractin, Centrin.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center.
Protein: QUEA_FRAT1
Sequence: MFMKTDDFDYKLPEELIASYPLENRDASRLLKLNKQTGEIADYKFTDFIDFINPGDLLVFNNSKVMLARLYGSKTTGAKLEYLIERIKTPKLFETHIKANRSPAIGSEIYVEDTLAKVLDKDGGMYLLEIQGDKDIYQLMEEFGHIPLPPYMKRDDEEFDAERYQTVYAQDLGSVAAPTAGLHFSKELMQQIKDKGVDIAYITLHVGSGTFKPVQVDDVESHKMHAEVISVPVEVCQKIRQTKENGGRVIAIGTTSVRSLETAGQNGQIEPYQGETDIFLYPGKKFNVVDAMITNFHLPKSTLIMLVSAFADKEKIIKAYEHAIAERYRFFSYGDAMFIF
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JADE1_BOVIN
Sequence: MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRPEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEYVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKAEEGLGEGTAQENGAPECSPRDPLEPFAGLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVMTDTDTL
What is the function of this protein?
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity.  Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation.  May also promote acetylation of nucleosomal histone H4 by KAT5.  Promotes apoptosis.  May act as a renal tumor suppressor.  Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.
What are the official names of this protein?
Protein Jade-1, Jade family PHD finger protein 1, PHD finger protein 17.
What is the protein family that this protein belongs to?
Belongs to the JADE family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to the ciliary transition zone.
Protein: RSMJ_COXBN
Sequence: MNDTLAITYSTPARLSEAEKLARQMKLPLVSLNSTDYSFLLVFTPAHLELRSTGTKAPGPLYVDFLKGATAHRRLFGGGRSQLIVRAVGLKSHPHPTILDLTAGLGRDAFVLANFGCDVLMIERNPVIALLLRDGLERAQSVEWFKSLKLELIEIDAQIYLSTLKKQFDVIYMDPMYPIRKKSALVKKEMRILRRLVGADDDAPQLLALALKKAKHRVVIKRPLLSNPLPGPAPDVVYEGKSSRFDVYLLKPSS
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRA_LACLS
Sequence: MSSTVIILIVVLLVILVAFYAFAILMRKKTEDRILALEERKESLFDLPVQEEIDSVKKMHLVGQSQTIFREWNQKWLDLSSNSFADLEEHIFEAEQLNDSFHFFRARESVADSEAQIEMMEGDVEGIRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNADLYGTVITELEKHLANIETEFSQFVTLNSTGDPIEAAEVLETAEEHTIALRAITEQIPSFIKTIEKDVPKRLEELQEASDKFIAEDYILPENVNLKERMDDLQHHLEESSSLLEQFELDRVEAELDLIQERVEELYSIFEREYSARRNVEKRSSVLKEYIEHIRVNNKNLLLEIDHVTQAYILSGNEKGYVRGYQEHLESLDADVDEIIANIEAKAIPYSSLSRRVNSVVNSLEDIEKNQIKISETLSGLRDEERAAQEIAERFDSELRTIKRYVEKCNLPGLPKDYLDLFFMTGDRVQNLFKELGRVRINIDTINHLVDVSTEDMHVLKEATTNLTDHAVLAEQLIQYANRYKASNEQVAQGISRALQLFENSRDYDGSFDEISKTLEIVEPGAASRISGVYFKNKPTPDYL
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: COX1_WHEAT
Sequence: MTNMVRWLFSTNHKDIGTLYFIFGAIAGVMGTCFSVLIRMELARPGDQILGGNHQLYNVLITAHAFLMIFFMVMPAMIGGFGNWFVPILIGAPDMAFPRLNNISFWLLPPSLLLLLSSALVEVGSGTGWTVYPPLSGITSHSGGAVDLAIFSLHLSGISSILGSINFITTIFNMRGPGMTMHRLPLFVWSVLVTAFLLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVSTFSRKPVFGYLGMVYAMISIGVLGFLVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGIKIFSWIATMWGGSIQYKTPMLFAVGFIFLFTIGGLTGIVLANSGLDIALHDTYYVVAHFHYVLSMGAVFALFAGFYYWVGKIFGRTYPETLGQIHFWITFFGVNLTFFPMHFLGLSGMPRRIPDYPDAYAGWNALSSFGSYISVVGIRRFFVVVAITSSSGKNQKCAESPWAVEQNPTTLEWLVQSPPAFHTFGELPAVKETKS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DXR_ACIF2
Sequence: MEMTRGICILGATGSIGKSTLDVVSRHPDQFRIVALTGNHRVAEMQLLCQQHHPELVVMAAPEAAQQLRVGLGDAGLKKIQVESGPEALAEAARMSGVDEVMAAIVGAAGLLPTLAAVEAGKKVYLANKECLVMAGNLFMERVRQHQVTLLPIDSEHNAVFQCFADGKGVRRILLTASGGPFRTWPAEHLAVVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFDLPASRIDVMIHPQSIIHSMVEYVDGSVLAQLGNPDMRTPIAHALAFPERMESGVSSLDLAHGPDLQFEAPDLQRFPCLALAFDALQAGGAAATVLNAANEIAVQAFLEGHLPFLRIAAVVEDTLGELQPAAPDHLDDVLAIDQLAREVALRHLARHGSGMQ
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MATP_VIBA3
Sequence: MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISDNMSPELDNKLKQAIRAKRKRHFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTNLKEDLSKLLSDDK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_ACIBY
Sequence: MTQSVCILGVTGSIGRSTLKILGQHPDKYSVFAVSAHSRISELVEICKQFRPKVVVVPEQKIAELKTLFAQQNISDIDVLAGQEGLVDIASHTDVDIVMAAIVGAAGLLPTLAAVKAGKRVLLANKEALVMSGEIMMQAARDHQALLLPVDSEHNAIFQSLPHNYLQADRTGQPQLGVSKILLTASGGPFLNHSLEQLVHVTPQQACKHPNWSMGQKISVDSATLMNKGLELIEACHLFSISEHFVTVVVHPQSIIHSMVQYVDGSTLAQMGNPDMCTPIAHALAWPERLQTNVPALDLFEYSQLNFQAPDTQKFPALNLARQAMRAGGLAPTILNAANEIAVEAFLMERIGFTSIPQVVEHTLEKLENAAAESIECILDKDKVARSVAQQYISSIGG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: UBC84_DROME
Sequence: MAATRRLTRELSDLVEAKMSTLRNIESSDESLLMWTGLLVPEKAPYNKGAFRIEINFPPQYPFMPPKILFKTKIYHPNVDEKGEVCLPIISTDNWKPTTRTEQVLQALVAIVHNPEPEHPLRSDLAEEFVREHKKFMKTAEEFTKKNAEKRPE
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-18 kDa, E2 ubiquitin-conjugating enzyme 84D, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: ACYP2_HORSE
Sequence: MSTARPLKSVDYEVFGRVQGVCFRMYAEDEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSNFSVRY
What is the function of this protein?
Its physiological role is not yet clear.
What are the official names of this protein?
Acylphosphatase-2, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: IFT57_XENTR
Sequence: MSEDSRRVEDDDRGPGAAYQAFLMMEDLLDKLKLLSYEDEVLRKQNMKPLSRHYFALPTNPGEQFYMFCTLAAWLISKAGHHFDQPQEYDDPNATISNILSELRSFGYSVDFPPSRLKAGYGEQVCYVLDCFAEEVLKHIHFSWKRPTYPTEEQDEENVIEDDAELTLNKIEDEIAEEDSDNDQEHFIDLNALSAQTQKLNTKESSKPEEILESNTDAAEWILEVERVLPQLKVTIRTDNKDWRVHVDQMHQHRDGIDTSLKETKGYLDKLHNEVAKALEKVSSREKYINNQLEQLVQEYRSVQAQLSEAKERYQQASGGVTERTRILAEITEELEKVKQEMEEKGSSMTDGAPLVKIKQALTKLKHEIVQMDIRTGVVEHTLLQSTLKEKSNMTRDMHALNIPESSIGAY
What is the function of this protein?
Required for the formation of cilia.  May also have pro-apoptotic function (By similarity).
What are the official names of this protein?
Intraflagellar transport protein 57 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT57 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: PSF3_SCHPO
Sequence: MDYYDIDSILSENQKVPCTSTVSIPGLGHEGRMVPTGSKVELPFWLAEVLAINSFVSIHMPAPFSSVVRNALKANPNSVSIRDITTHYYHFAEKMLHLISDDSLVQISLNTLRSRAMLIADASLNPQGALQQNSQFIEGLDDFEKHILRVSHNAHRSLINWQNSTS
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein psf3.
What is the protein family that this protein belongs to?
Belongs to the GINS3/PSF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MALE_KLEAE
Sequence: MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVSVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGAYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPVAVEALSLIYNKDLVPNPPKTWEEIPALDKALKAKGKSALMFNLQEPYFTWPLIAADGGYAFKFENGKYDVKNVGVDSAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTFKGKPSKPFVGVLSAGINAASPNKELAKEFLENYLMTDPGLEAVNNDKPLGAVAVKSFQEKLEKDPRIAATMANAQKGEIMPNIPQMSAFWYAVRTAVINAASARQTVDAALKDAQGRITK
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Binds maltose and higher maltodextrins.
What are the official names of this protein?
Maltose/maltodextrin-binding periplasmic protein, MMBP, Maltodextrin-binding protein, Maltose-binding protein, MBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MAP1A_ARATH
Sequence: MASESDASSIATLSCARCEKPAHLQCPKCIDLKLPREQASFCTQECFKAAWSSHKSVHVKAQLSSIGDQNSDLISQGWLYCVKKGQARTPKLPHFDWTGPLKQYPISTKRVVPAEIEKPDWAIDGTPKVEPNSDLQHVVEIKTPEQIQRMRETCKIAREVLDAAARVIHPGVTTDEIDRVVHEATIAAGGYPSPLNYYFFPKSCCTSVNEVICHGIPDARKLEDGDIVNVDVTVCYKGCHGDLNETYFVGNVDEASRQLVKCTYECLEKAIAIVKPGVRFREIGEIVNRHATMSGLSVVRSYCGHGIGDLFHCAPNIPHYARNKAVGVMKAGQTFTIEPMINAGGWRDRTWPDGWTAVTADGKRSAQFEHTLLVTETGVEVLTARLPSSPDVYPWLTK
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 1A, MAP 1A, MetAP 1A, Peptidase M 1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_SALDC
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWENITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MRAY_VIBPA
Sequence: MIIWLAELLQPYLSFFRLFEYLSFRAILSVLTALGLSLWMGPIMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGIMILAAISITILLWTDLSNPYVWAVLTVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSLIAFVVAFALYAYGKDTAATQLVVPFFKDVMPQLGLMYIILTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSEYLHIPYLPHASELVVVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.