PharMolix/UniProtQA huggingface dataset:
Protein: NADA_BURTA
Sequence: MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHYYVDAELQELADETGGCVADSLEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVANLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPESPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNVLSNLADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQASGDLLRDQQLFANVGAA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_XANP2
Sequence: MNWISNVVRPKIRDFLARREVPENLWVKCPETGQMVFHKDLEANLYVIPASGYHMRMDAVKRLKATFDDGAYEEVALPEVATDPLKFRDERRYIDRLKDARTKTGYQDAVKVATGMLTELPVTIAVQDFGFMGGSLGMAAGEAVVKGLQTAAEKGTPFIMFAASGGARMQEGILSLMQMPRTTAAIQELRETRKPYIVVLTNPTTGGVTASYAMLGDIQIAEPGALIGFAGPRVIEQTIREKLPDGFQRAEYLHEHGMLDMVVHRHQMRDTLGRLCRMLMKAPALPPKGRLPRPEAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_NOSP7
Sequence: MPVIEKKRTRDLPQINERIRFPKIRVIDTDGAQLGIMPPQEALQLAEEKELDLVLISDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGELQQAPKKEGRNMMMLISPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD1_AROAE
Sequence: MSDPTRPARIDERSRNVTEGVMRAPNRSMYYAMGYRETDFGKPMVGVASAHSTITPCNSGLQPLADTVAAALKEAGANPQLFGTPTVSDGIGMGTEGMKYSLVSREVIADSIETCVNGLWQDGVVVIGGCDKNMPGGMMALVRTNVPGIYVYGGTIKPGHYKGRDLNIVSVFEAVGEFIAGQLDPVDFKEIEKRACPGSGSCGGMYTANTMSAAFEALGMSLPYSSTMANEDAEKLASAAESARVLVEAIKRGLRPRDIVTREAIENAVSVIMATGGSTNAVLHFLAIAHAAEVPWTIDDFERIRRRVPVIVDMKPSGRYLATDLHQAGGIPQVMKLLLDAGLLHGACVTITGQTIAEVLENVPAAPRADQGVIRTLSDPLYAEGHLAILRGNLSPEGCVAKISGLKNPAITGPARVFDSEDDAMAAIMARRIVEGDVVVIRYEGPKGGPGMREMLAPTSALVGQGLGESVGLITDGRFSGGTWGMVVGHVSPEAFVGGPIALVREGDSVTIDAHRQLVQLNVGDEELARRAADWTPPSPRYTRGVLAKFAKFASSASKGAVTDLDL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 1, DAD 1.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PAND_SALA4
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWRPKVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_BRADU
Sequence: MNEQPENLRNFTINFGPQHPAAHGVLRLVLELDGEIVARVDPHIGLLHRGTEKLIEQKTYLQAIPYFDRLDYVAPMNQEHAFCLAAEKLLGIEVPRRGQLIRVLYCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGSRMHAAFFRVGGVHQDLPQKLVDDIEAWCDPFLKVVDDLDRLLTANRIFKQRNVDIGVVPLKEAWEWGFSGVMVRGSGAAWDLRKSQPYECYAEMDFDIPIGKNGDCYDRYLIRMEEMRQSVRIMRQCIQKLNAPEGKGPVVVEDNKVAPPRRGEMKRSMEALIHHFKLYTEGVHVPAGEVYAAVEAPKGEFGVYLVADGTNKPYKCKIRAPGFAHLQAMDHICRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COAA1_HUMAN
Sequence: MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM
What is the function of this protein?
Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
What are the official names of this protein?
Collagen alpha-1(X) chain.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CCD63_MOUSE
Sequence: MKKVRRKGSSGLSELSEKAREQLAQAELRKLRQQFRKMVDSRKSFNFRHQRMIAGQYKEIETLKAEQAETTMLLSLVKSPKNLDINQKNFMELRFLLQTKGDYEALISSMKVLLGELDDKIVQMERKITNQRQLFLRTQEANNPKRLQRQIHVLESRLNLVTVHFDTMLTSNSQLRKEIEDLLFEKAAYDHVYQQLQRRLQTQKKTMNVAIEQSAQAYEQRVEAMARMAAMKDRQQKDISQYNLEIRELERLYDHETKLKSFLLAKLNDRSEFEDQAKKQEDVKSKKLGKKGKGESFASYEVAHLRLLKLAENGDLNQLTEDFLAKEEKNFARFTYVTELNNDMETMHKKTQRIQDDIINLRSQQQTSHEGTRSILKQMEEKLRKTTQEADIYETKYKEMSKTLEYLKNSVEKMFKKINCDATEILGKLGESGKVTDINLQQYFAIIEKKTNDLLLLESFRRLQEAEGPDVDVPQPFVNPFWGGSALLKPPEPIRVVLPVFGADSFSDKLEEVDSPLDHSTLQQMVLENFLQRERTKELQDTMSEKGDEIRLKKKVIG
What is the function of this protein?
Plays a role in spermiogenesis (PubMed:26501274).  Involved in the elongation of flagella and the formation of sperm heads (PubMed:26501274).
What are the official names of this protein?
Coiled-coil domain-containing protein 63.
Protein: GROA_CRIGR
Sequence: MAPATRSLLRAPLLLLLLLLATSRLATGAPVANELRCQCLQTMTGVHLKNIQSLKVTPPGPHCTQTEVIATLKNGQEACLNPEAPMVQKIVQKMLKSGIRK
What is the function of this protein?
Has chemotactic activity for neutrophils.
What are the official names of this protein?
Growth-regulated alpha protein, C-X-C motif chemokine 1.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAP1B_ORYSI
Sequence: MSDGKDSLDLSGLGAAVPNAKELSAEDKANLVESIKNTLQGLAARHTDVLESLEPKVRKRVEVLREIQSQHDDLEAKFFEERAALEAKYQKMYEPLYSKRYEIVNGVVEVDGVTKEAADETPAEQKEEKGVPEFWLNAMKNHEILSEEIQERDEEALKYLKDIKWYRISEPKGFKLEFYFDTNPFFKNSVLTKTYHMIDEDEPILEKAIGTEIEWFPGKCLTQKVLKKKPKKGSKNTKPITKTENCESFFNFFSPPQVPDDDEEIDEDTAEQLQNQMEQDYDIGSTIRDKIIPHAVSWFTGEAAQDEDFEGIMDDEDDDDEDDDDDEDEDDEDDDEDDEDEKKGGRVPSGEGQQGERPAECKQQ
What is the function of this protein?
May modulate chromatin structure by regulation of nucleosome assembly/disassembly.
What are the official names of this protein?
Nucleosome assembly protein 1;2, OsNAP1;2, Nucleosome assembly protein 1-like 2, OsNAP1_L2.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RIMP_RHOPT
Sequence: MTEPTPAVPETDDLAEPRLVIEPGVAARFCAVAEPVLMAMGYRLVRIKVSGDAGCTVQIMAERPDGTMLIDDCEAASRALSPVLDVADPIDRAYRLEISSPGIDRPLVRRSDFARYAGHLVKIEMAVPHQGRKRYRGLLDGVEGDAVRVQREGATKDEDPLVLLPMHDIGDARLVLTDELIAESMRRGKQAERDLKQSLGLAPEPPPHAKRSDPKKSHAPKRGPKAAKAPTKPKPQNTKQHRLAADKARRGEIDTSEGD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_FRATH
Sequence: MKNKNSEQNTHYTIGEQDIHYFHEGKHIYAYEFMGAHKACEEGIEGIRFTTWAPNAKSICVIGDFNYWQVEDKNYMEPITDAGLWSVFIPNAKNGDKYKFVVTNKDTSHYVYKSDPYAFFSELRPNTASIITTETQYTWSDDKWLEKRAKTNYYDNPMNVYELHLASWKTKNGKFLTYDELSETLPQYIKEMGYTHVEFMPLHEHPLDASWGYQPTGFYSVNSRHGDIIGLKRLVDKLHNNDIGVILDWVPGHFCKDQHGLIYFDGSPCYEYQEPTKAINKGWETHNFDLGRNEVKCFLISNAMYWINEFHIDGLRVDAVSNILYLNYDREDGQWIPNIYGGHENLEGIAFLKELNGVLKHTCKGVITIAEESSSWPDISTPVEKGGLGFDFKWNMGWMNDTLRYISLDPVYRKYHHNLITFSMVYHYSEKFILSISHDEVVHGKKSLINKMWGDLWNKYAGLRLYMSYMIGHPGKKLIFMGSEFVQFVEWREYEQLQWQVVDQYESHKQTLHFFKKLNDFYHNETALWQCDYDHHGFRWIDANNSQQSILSFIRSSKDNKQKLIFICNFTPVTYYDYHLGVPDAGSYKEVFNSDNLEFGGSGQVMATEIFSSPQSSHGFEQRIIIKIPPMATLVLKLIK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: FRIH_CRIGR
Sequence: MTTTALTTASPSQVRQNYHQDSEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHSES
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin heavy chain, Ferritin H subunit.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: COBT_RUEST
Sequence: MLPDLTTLSDFRNALAQAPGADADARAACEDRNGQLTKPPGALGQLEEIAIWYGSWRGTARPEVRAPQVIVFAGNHGVTARGVSAFPAEVTVQMVANFKAGGAAINQLAQLADARMDVHALELDRPTADFTQGPAMSEEDLLAALRTGWNAVDPASDVLVVGEMGIGNTTSAAAICHALYGGEPGDWTGRGTGVDDEGLALKTAVIAEAVALHGSRDGLEVLRCLGGREIAAMAGAIAAARVLRIPVILDGFICCAAAASLARLHDQALDHAVAGHQSAEGGHQALLARLGKAPLLSLGLRLGEGSGAALAIQVLKGALACHSGMATFAEAGVSDG
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: Y1103_BACVZ
Sequence: MAKESSFDIVSKVEFPEVQNAIQMTLKEIGTRYDFKGSKSDVTLEKEELVLISDDEFKLNQLKDVLSGKLIKRDVPTKNIEYGKIENASGGTVRQRAKLVQGIDKDNAKKINAVIKNSGLKVKSQIQDDQVRVTGKNKDDLQQIIAAVRGADLPIDVQFINFR
What are the official names of this protein?
UPF0234 protein RBAM_011030.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ADAS_DROME
Sequence: MAAKRNAVTTEAPESSAPGEGTALALDSRLSKRVESVIPKKRHEALKWFGWGYNDSQFYGKDGIICFRGEKYPLGGCELPSFTKWVEKKFDLRVDTTKQYPQLPRTYPRPVENAPFLHELKGTTQVDYSAEGIDRLVRCHGQTLNDIYSLWHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQNESRMICALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLGGWVATRASGMKKNVYGNIEDLVVRVRMVTPSGTLERECSAPRVSCGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVARRRCQPASVRLMDNEQFMFGQALKPEKSWWASVVDAMKQRYVTSWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQGFPAGGQNGERGYILTFVIAYIRDFGLHQGIVAESFETSVPWDRCSLLCRSVKQRVVSECSKRSINYYTISCRVTQTYDAGACIYFYFGFRSTDVADPVELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNIFALGNLLPLEEAQASPPPPTSSTPPKAKL
What is the function of this protein?
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
What are the official names of this protein?
Alkyldihydroxyacetonephosphate synthase, Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PPP5_CAEEL
Sequence: MAATITDDIVATVLESIEEKSYEDEKEKAGMIKDEANQFFKDQVYDVAADLYSVAIEIHPTAVLYGNRAQAYLKKELYGSALEDADNAIAIDPSYVKGFYRRATANMALGRFKKALTDYQAVVKVCPNDKDARAKFDECSKIVRRQKFEAAISTDHDKKTVAETLDINAMAIEDSYDGPRLEDKITKEFVLQLIKTFKNQQKLHKKYAFKMLLEFYNYVKSLPTMVEITVPTGKKFTICGDVHGQFYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTMIGFKLLYPNHFFMSRGNHESDVMNKMYGFEGEVKAKYTQQMCDMFTETFCWLPLCHLINEKIFVCHGGLFKEDGVTLEDIRKTDRNRQPPDEGIMCDLLWSDPQPINGRSPSKRGVGCQFGPDVTSKWCETNGIEYVVRSHEVKPEGYEMHHNGQCFTVFSAPNYCDQMNNKGAFITITGDNLTPRFTPFDAVPHPKLPPMAYANSLFGFN
What is the function of this protein?
Serine/threonine-protein phosphatase (PubMed:23569206, PubMed:26593036).  Dephosphorylates cdc-37 (PubMed:23569206).  Probably by dephosphorylating separase sep-1, may be involved in sep-1-mediated exocytosis of cortical granules during meiotic anaphase and mitotic cytokinesis (PubMed:21878498).
What are the official names of this protein?
Serine/threonine-protein phosphatase 5.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic localization during interphase, enriched at the mitotic spindle matrix during metaphase and released from the spindle during anaphase.
Protein: SPEE2_CALS4
Sequence: MILKLEVGVGLKNLNGKWGLDSSKEFYWEPDVEGGYRVYKVKSVIIEHQSLYQKIDIVELETWGKSLFLDGSLQSTESDEFIYHELLVHPAMRVHPSPKRVLICGVGEGKSVREVLKYPTVKEVIGVDIDKEVVALCQKHLGKTPIDDKRVRLVYQDVAEFIKNYRGEPFDVAIVDVTDDLDGPARSVHQLDFYKRLYEILGEKATVVVQGTSAFSKVKNVGFCHIYEILKEVFPFVIPYADYIPSFSDLWTFFVALKGIKDLTPRHEIPRDLKYYDEYTNERIFTLAKPLREKLGV
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase 2, Putrescine aminopropyltransferase 2, PAPT 2, Spermidine synthase 2, SPDS 2, SPDSY 2.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ACICJ
Sequence: MARIAGVNIPSNKRVLISLRYIYGIGPAKAREICQSLEIGEDKRVNQLSEDEIMKIRELIDRDYRVEGDLRREVAMNIKRLVDLGCYRGLRHRKGLPVRGQRTHTNARTRKGKAVAIAGKKKATR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: HDHD3_DANRE
Sequence: MRVPVRWVLWDVKDTLLKVRRSVGEQYCREAQQAGLQLSPAQVETAFRLAYKQKSQLLPNYGRAQGMDSQVWWTGLVRDTFGQCGVHDPALLDKLANNLYHNFCGPENWEVFSDSNSTLKSCTALGLKQGVVSNFDRRLEGILRGCGLLTHFSFIVTSEDARVAKPDPAIFSQALERCGVPASSVVHVGDHYVKDYLTSRSLGIRGYLLNRKDGQKTHLDIPPEHILQSLDELPARLQHNTD
What are the official names of this protein?
Haloacid dehalogenase-like hydrolase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: DHOM_MYCTU
Sequence: MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVVQGVSSVIRLEGTGL
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: SYS_HISS2
Sequence: MIDPTLLRNNLSEIAEKLKVRRGFILDVDKFSQLEEQRKTLQIKTETLQAERNSRSKTIGAAKARGEDISTLLAEVDHMGAELNTVKEELANVLTEIEQLALTIPNIPADEVPLGKDDSDNKEVFRWGTPKKFDFEVKDHVALGEILGGLDFAAGVKLSGARFAVIKGQIARMHRALAQFMLDLHTEQHGYTEAYVPYLVNHTTLYGTGQLPKFGEELFHIKPLENEQTYALIPTAEVPVTNLVRDEIIDEADLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVEPEKSMEALEELTNQAEKVLQLLNLPYRKVLLCTGDMGFGATKTYDLEVWIPAQNTYREISSCSNMWDFQARRMQARCRAKGDKKTRLVHTLNGSGLAVGRTLVAILENYQNADGSITVPEVLRPYMNGIEIIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVC7
Sequence: MAARLCCQLDPARDVLCLRPVGAESRGRPFSGPLGTLPSPSSSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTFARRMETTVNAHQVLPKVLHKRTLGLSAMSTTDLEAYFKDCVFKDWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: Y1463_STAA3
Sequence: MDMNFDLYMNGVVEQARNEIESAGYEQLTTAEDVDKVLKQDGTTLVMINSVCGCAGGIARPAASHALHYDVLPDRLVTVFAGQDKEATQRAREYFEGYAPSSPSFALVKDGKITEMIERHQIEGHDVMNVINQLQTLFNKYCEER
What are the official names of this protein?
UPF0403 protein SAUSA300_1463.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: A1IB6_LOXHI
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAIGDVAKAYKKAGVSGHVWQSDGITNCLLRGLSRVKDAVANRDSGKGYINKVYYWTVDKRATTRDALDAGVDGVMTDYPDVIADVMNEAAYKNKVRLATYEDSPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2bvi, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_CHLCV
Sequence: MKKNTHPEYNKVLFVDSSTGYKFVCGSTYQSDKTEVYEGQEYPVCYVSVSSSSHPFFTGSKRLVDAEGRVDKFLKRYSNAKPAQPVQAPAEEGPVVKGKKKAPAKKKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ATP6_PSEF5
Sequence: MSAETTASGYIQHHLQNLTFGQLPNGSWGFAHSAAEAKEMGFWAFHVDTLGWSVALGVIFILLFRMAAKKATSGVPGALQNFVEVMVGFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNAIDLVPVDWIPQLAMLISGDQHIPFRAVSTTDPNATLGMALSVFALIIFYSIKVKGIGGFIGELTLHPFGSKNILVQALLIPVNFLLEFVTLVAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGMGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_SULTO
Sequence: MKDIISVYDFSKSDFDELFELADKLRNMSTYPKILKEKTVALAFFEPSTRTYLSFNKAAINLGASTIGFSGEEGTSIAKGENLADTIRMLNNYADMIVIRHKFDGAAKFASEISEIPVINAGDGKHEHPTQTVIDFYTIYRNFKNIDGLTFGLMGDLRYARVVNSFLRALTRFKPKKVYLISPPQLSARKEILEELNYPYREVIDYNEVIEEIDVLYVTRIQKERFPDESEYEKVKESYVVDMNLVSKMKKDAIILHALPRVNEISREVDKTPQAKYFEQASYAVPVRMAIFHKIVGE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.