PharMolix/UniProtQA huggingface dataset:
Protein: TRXH4_ARATH
Sequence: MAAEEGQVIGCHTNDVWTVQLDKAKESNKLIVIDFTASWCPPCRMIAPIFNDLAKKFMSSAIFFKVDVDELQSVAKEFGVEAMPTFVFIKAGEVVDKLVGANKEDLQAKIVKHTGVTTA
What is the function of this protein?
Thiol-disulfide oxidoreductase probably involved in the redox regulation of a number of cytosolic enzymes.  Possesses insulin disulfide bonds reducing activity.
What are the official names of this protein?
Thioredoxin H4, AtTrxh4, Thioredoxin 4, AtTRX4.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_PSYIN
Sequence: MKITLPEYDKAQVLVVGDVMLDRYWHGPTARISPEAPVPVVKVEQIEERPGGAANVALNVAALGGKVNLIGLVGDDEAANVLVKNLKSVHVNTDFVSVPNFPTITKLRVLSRHQQLLRLDFEEGFEGIDSTDILEKMHASLTRQPSVVILSDYNKGSLADVQKMIQLAKKFNSVVLVDPKGSEFEKYRGATLLTPNLAEFEAVVGKCHSEKELVERGLALIKELDLDALLVTRSEHGMTLLREGQEPLHLPTQAQEVYDVTGAGDTVISVLASSLAAGSSFEQACTLANAAAGVVVGKIGTSTVNTIELANAVYSQQEIGFGVLSEEQLKLAVKLAQHRGEKVVMTNGCFDILHAGHVSYLNTAREQGNRLIVAVNSDQSVRNLKGQGRPVNPVDRRMAVLAGLGAVDWVIEFTEETPQRLIAEILPDLLVKGGDYLPEDIAGGKEVIANGGEVRVLQFEEGCSTSEIIKTIRNNS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RLMI_CROS8
Sequence: MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKAAPGETIDIVDHQGKWLARAALSPASQIRARVWTFDPNETIDIAFFTRRLQQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGNFLVLQLLSAGAEYQRPALVSALQALYPECAIYDRSDVAVRKKEGMELAQGPVSGELPPDLLAIEEHGMKLLVDIKGGHKTGYYLDQRDSRFATRRYVEDKRVLNCFSYTGGFAVSALMGGCRQVISVDTSQDALDVAKQNVELNKLDLSKAEFVRDDVFKLLRKYRDQGETFDVIVMDPPKFVENKSQLQGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTTDLFQKIVADAATDAGRDVQFIEQFRQAADHPVIASYPEGLYLKGFACHVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC1_YEAST
Sequence: MFKEEDSLRKGQNVAAWKTLLAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNRYLTPFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSITREVRDIWKLEGLPGFFKGSIASMTTITLTASIMFGTYETIRIYCDENEKTTAAHKKWELATLNHSAGTIGGVIAKIITFPLETIRRRMQFMNSKHLEKFSRHSSVYGSYKGYGFARIGLQILKQEGVSSLYRGILVALSKTIPTTFVSFWGYETAIHYLRMY
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSAA_POPAL
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQLWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLVAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYAMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPRATAPGATASTSLTWGGDDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGTISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: 3MGH_RICTY
Sequence: MNKLIPLPREFFARDTNLVSTELIGKVLYFQGTTAIITETESYIGNDDPACHAARGRTKRTDVMFGPAGFSYVYLIYGMYHCLNFVTEDEGFPAATLIRGVYVISHNDLYTIYTAKVKSQITDEKTQSIIISEDRRSTKFDIPNLEESNLYLNGPGKLCKYLGINTTHNKCDLINNKDFFVSDIGLNLPYSTTKRIGITKGTDKLWRYIVTDNKNALLNINIL
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: TOTC_DROSI
Sequence: MNASISLLCFALLLISPFCLGYSDEERESDSLRVAEILQTSKDDESKINRTQELLDIFRRLAPSLSPEDRERIERSIKEHTDEILIDGVPSQGGRKTKYVGKILSPVAQGLAIGFFEELGGSLSRLFTG
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot C.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTAI_PESFW
Sequence: MPSPTNPAKVETPFTTAALGNGVDFWKAYVENRPHPSDSFFELISEYHHSHGDSAAQSAIAHDVGTGPGNIAEKLLRHFDHVVGSDVNEQALAAAPALLPADSIKRMTFVKSSAEDLASANIPESVGKGQTDLILVSECIPLLDISKAFAAFRALLRPGGTLAIYFYSRPIFTGDNEAELNQLYDRIATRVCQFLLPFKGTPGFPIHYRAAEAMSSGLDSIPFDPEAWQDVVRYKWNADVPLTFNSKEGYDFEVEPVDRRDHSTEITKEITDRDFWAEEWDIGRVASFLDSVFPNYRNKAGDKFEEVQSLFTELETALGGPKATRKVSFPVVLLLATRK
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulouchrin and chloroisosulochrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Methyltransferase ptaI, Pestheic acid biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: SPXM3_ARATH
Sequence: MVAFGKKLKERSIQEWQGYYINYKLMKKKVKQYSRQLEGGNLERRHVLKDFSRMLDNQIEKIALFMLEQQGLLASRLQTLRGSHDALQEQPDISHMSYLKEEYRAVGQDLLKLLFFVEMNAIGIRKILKKFDKRFGYRFTNYYVKTRANHPYSELQQVFRHVGLGAVVGAVSRNLHELQNNQGSYLSIYDQPVLPLQDPVVDSIRAAVDRLTRSTNFLHFMAQHALIMQEELPSPQDEEGEEEDGRYHFMSLLLNLVNTFLYMVNTYIIVPTADDYSMSLGAAATVCGVVIGAMAVAQLFSSVYFSAWSNRSYFKPLIFSSIVLFIGNLLYALAFDFNSIAVLLIGRLFCGLGSARAVNRRYISDCVPLKIRMQASAGFVSASALGMACGPALAGLLQIRFKIYKLTFNQDTLPGWVMAVAWLIYLVWLAISFREPAREPEEIPKTSEESNHSAVQDVNLEKGMKQPLLLTSEEIEEQGEDECDGSEEASEDSRTPANSILAAYRLLTPSVKVQLLIYFMLKYAMEILLSESSVITTYYFGWSTSSVAIFLFCLGLTVLPVNLVVGSYISNMFEDRQILLVSEIMVCVGILLSFHVVVPYTVPQYVCSGLIMFVSAEVLEGVNLSLLSRVMSSRLSRGTYNGGLLSTEAGTIARVIADATITVAGFFGRNMLLNVTLLPSLVICVLSIVATCFTYNSLY
What are the official names of this protein?
SPX domain-containing membrane protein At4g22990.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACHA5_BOVIN
Sequence: MAAPGWGRWVLGLGPLLLQVFLPFQLVAGRWGPEGAGGGVRRGLAEPSVVAKHEDSLFKDLFQDYERWVRPVEHLNDRIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKLIRVPSDSLWTPDIVLFDNADGRFEGASTKTVVRYDGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHDAMAPWVRKIFLHKLPKLLCMRSHVDRYFSQKEEARSSRGPRSSRNALEAALDSVRYITRHVMKETDVREVVEDWKFIAQVLDRMFLWTFLLVSVVGSLGLFVPVIYKWANIIVPIHIGNENK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CHLB_PINTH
Sequence: MKLAHWMYAGPAHIGTLRVASSFKNVHAIMHAPLGDDYFNVMRSMLERERNFTPATASIVDRHVLARGSRKRVVDHIIRKDKEEGPDLIILTPTCTSSILQEDLKNFVDRASIISDCNVIFADVDHYQVNEIQAADRTLEQVVRYYLEKSHTLDQFVTDAPSVNIIGILTLGFHNRHDCRELRRLLKDLDIRINQIIPEGGSVEDPKNLPKARFNLIPYREVGLMTAMYLNKEFGMPYVSTTPMGAVDMAECIRQIKKSLETLAAPILSSKRVDYESYIDGQTRFVSQAAWFSRSIDCQNFTGKETVVFGDATHAASITKILAREMGIRVSCTGTYCKHDAEWFKEQIKDFCDEIIITDDHAEVGDIISRVEPSAIFGTQMERHIGKRLEIPCGVISAPAHIQNFSLGYRPFLGYEGTNQIADLVYNSFALGMEDHLLDIFCGHDTKEIMTKSLSTDISPIWDPESRQELGKIPRFVRDEVKRNTEKFARRKGILNVTVEVMHAAKEALS
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRAM_I78A0
Sequence: MNPNQKIITIGSVSLGLVCLDILLHIISITITVLGLHKNGKQRRCNETVIREDNETVRIEKVTQWHNTNVIEYIEKLEGDHFMNNTEPLCHAKGFALFSKDN
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane (By similarity).
Protein: Y1001_ARCFU
Sequence: MRKFVAFFVIVALAALLAGCGGQGEQEQKPSEQKTTTTVAESKGIETLSDLYNSKKMVHGTAKVTLQGETTTVEFWYYFDMPNKETLLRYEGEQGGMGKMTAIIKNKYSGTTLTQTMYMKSEKMEAQGCDWIVITQTSTISQSESNIGDEPVEDAFKSTFASQGNVWEYEVETVDYNPSLFQPDGKVCQFSYGS
What are the official names of this protein?
Uncharacterized protein AF_1001.
Protein: SYR_HISS2
Sequence: MNIQSILSNKIKQAMRQAGADEQCDALVKPSSKPQFGDYQANGIMATAKKLGLNPRDFAQKVLDLIDLKNIAEKMEIAGPGFINIFLDKNWLAENIQVTLQDKKLGVTVEEIQTIVVDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMENEHASAMELADLEAFYRAAKEHYDNDETFAEKARNYVVKLQNGDAYCRTMWKKLVDITMQQNQRNYDRLNVTLTQNDVMGESLYNPMLPEIVADLKAQGLAVEDEGAQVVYLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYHTLKADRALVFSDTRQSQHMQQAWLITRKAGYVPDSFQLEHKNFGMMLGKDGKPFKTRSGGTVKLTDLLDEAIERADKLISEKSTALSSKEKAAVIEAVGIGSVKYADLSKNRTTDYVFDWDIMLSFEGNTAPYMQYAYTRIRSIFNKTDISEEQLHPAKIQLTDEKERLLAIKLLQFEETVQIVGKEGTPHILCAYLYELAGLFSSFYEHCPILNNDNENVKLSRLKLALLTEKTLKQGLDLLGIKTVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHSA5_PONAB
Sequence: MGFGATLAVGLTIFVLSVVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL
What is the function of this protein?
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
What are the official names of this protein?
Protein shisa-5, Scotin.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.
Protein: CEMA_STIHE
Sequence: MTELEKIGLIPRSIVRMLDRFYYQIYLGTAEPLVKQFRFSKYLLLTSVKSLFVVLFIPFFINIFTKIYVFRPLVEYFWDRKQTEIFLNYELQEKAFSEIRNFEEKMYFDYLIKTENFFPEKPKYFLPEAPLPGELPMQKKELFGVNLQEYKFKSNHSCLKFYSTEANSSVFGFENGNSLKLSHVSLFASKYPIKFTVIKNDLFKIKNQEGKSGAFPASEEEKKLKKGEKALLFPLLPTFSFSPRKNSSFFLGEKENMGISPGSKEEKKLKFFFFPHSGGTFSHCSLGIEDSEGKFSPGRREISPLLPGEHCGKLGKNAIFLLEEEKNGSGETRASFATSGSKAPALEELKNQSIDFLIPLEKSSPQRTFFSQHLASDFCSFDLTAQTKFHFVSFPNSIDTVPYNFNKNTESIFRQKTRELANHYNNESISAITNLLADFMGLFILLFLLVNMKMSLMNTTAFLSESFFSLKDSKKAFLMLLFTDLLVGFHSPRGWEVIFHFLFEHFGLPENHNIIFLLVGTFPVLLDALFKYWIFRHLNRHSPATVATFQAMVE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: TNNC1_COTJA
Sequence: MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDQFLVMMVRCMKDDSKGKTEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGNKNNDGRIDYDEFLQFMKGVE
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, slow skeletal and cardiac muscles, TN-C.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: EIPR1_DANRE
Sequence: MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGNHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL
What is the function of this protein?
May act as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network.
What are the official names of this protein?
EARP-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIPR1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network.
Protein: BGB_DROME
Sequence: MMNEAALANMIPYDTIGLYEQPKPRFIFKMPRVVPDQKSKFESDELFRRLSRESEVRYTGYRERSIEERQVRFMNGCREGHTEASFVASGTNLQLVFNANQNPYLHDKECDFDKEHGKVHIKSYFIMNGVCVRFRGWIDLERLDGVGCLEYDERRAMHEDAILRDQIDRYNQRLREFEDTKRAYRDNRQDEMEAVRRGVASGGIGVGASMWRR
What is the function of this protein?
Regulates the DNA-binding properties of Runt.
What are the official names of this protein?
Protein big brother.
What is the protein family that this protein belongs to?
Belongs to the CBF-beta family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAB4B_HUMAN
Sequence: MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (By similarity).  Protein transport.  Probably involved in vesicular traffic (By similarity).  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).
What are the official names of this protein?
Ras-related protein Rab-4B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RLME_SHEPC
Sequence: MSGKKRTASSNRWMLEHFDDHYVKLAQKRGLRSRAAFKLEELQQKDQLIRPGMTVVDLGAAPGGWSQVAVKLVGDRGKVIACDILPMDPIVGVDFLQGDFREEKVLEALLTRVGADKVDVVLSDMAPNMSGSDGVDQPRAMYLVELALDMCHQVLAPNGSFAVKVFQGEGFDEYMKAVKEAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1191_ROSDO
Sequence: MTQMPQTNARVHAGRMAYHAGLSAEASVIREYESHGYVFEAQRWRGQVGEIDLVLRKSGLVVFVEVKKSKSFERAALRISPTQKRRIFATGEEFVAQEPQGLLTDMRFDVALVDAAGAVQILENALSEG
What are the official names of this protein?
UPF0102 protein RD1_1191.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: YHCG_BACSU
Sequence: MEIKLEHVSKKYGRHTAVNDVSITLSSGRIYGLIGPNGSGKSTTLKMMAGLLFPTSGFVKVDEEQVTREMVRQTAYLTELDMFYPHFTVKDMVNFYQSQFPDFHTEQVYKLLNEMQLNPEKKIKKLSKGNRGRLKIVLALARRADVILLDEPFSGLDPMVRDSIVNSLVSYIDFEQQIVVIATHEIDEIETLLDEVIILANGEKVAQREVEDIREQEGMSVLQWFKSKMEVC
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YhcG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: G6PI_BAUCH
Sequence: MKNINPINTNAWNSLQQHFNNIKEVKIRDLFLLDSQRFDNFSAIFDNQILLDYSKNRITTETLYLLFALAKECDLPNAIAAMFSGQKINRTEDRAVLHIALRNRSNKIIAIDSQDIMPEVNAVLSKMRQFCNQIISGQWKGYTGKPITNIVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHITEKFKYLDPETTLFLIASKTFTTQETMTNAHSARNWFLKTAVNEQYIAQHFVAISTNANDVVKFGININNMFQFWDWVGGRYSLWSAIGLSIALSLGFENFELLLEGAHAMDCHFTETQLEHNLPVILALINIWYNNFFGFETEAIIPYDQYMHRFAAYLQQCHMESNGKSIDRNGNIINYQTGSIIWGEPGTNSQHSFYQLLHQGTKIVPCDFIVPAISHNPLGDHHLKLLANCFAQTEALAFGKSCQFIEEKFIMGTTSEQKLSIIPFKVCGGNRPTNSILVKQITPYNLGALISLYEHKIFTQSVILNIYAFDQWGVELGKTQANSVLSELATDNIVTCHNSSTNGLINYYKSWRYKTDDK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_ENT38
Sequence: MRLVQLSRHNIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAILEPSQFHLSRSMKRFHAKSPYRVTLNYAFGQVIEGCAADRDEGTWITHDIINAYLRLHELGYAHSIEVWDNDTLVGGMYGVAQGTLFCGESMFSRAVNASKTALLVFCQEFSLRGGQLMDCQVLNEHTASLGAVEITRRHYLDELGNLRQQKLPQNFWVPRTLFMPQV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA3_STAAB
Sequence: MEFVAKLFKFFKDLLGKFLGNN
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 3 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: OPA3_SCHPO
Sequence: MSSLALKIGSLLVRTLSKPIANTIKAQAKEHKAFRKACIEFAQWMHRAEFRITGINRAKSGGANVRLRPLNDAKAVDAGATFLSETFIFTVAGGAILFETWRARRKEKNRRDEVAEAILGLQHEIVRINEIMEKQFVLQKKKNELQSSTEEIDSTEKDFDELHKVILKVERELHTLRQNTPSQNEQAEATPSKEIPRETVSEKADHPPSSNTKSVSTG
What are the official names of this protein?
OPA3-like protein.
What is the protein family that this protein belongs to?
Belongs to the OPA3 family.
Protein: KNG_SALSA
Sequence: MKLGVRLCVLVVFSLQLWGPGQGQELEPEQVLAFCDDKDVEAAVDLALVKYNQKLPYGNQLALYQILESSKAQNDSCTQYFVEFNSRVTDCPAGGDKVWRDCDYLPTGNKVPRPCKATVHMSETDKKVLAVFCDPVEAPVVAERTTCLGCPREIDVESEDLKDPLTYSITRFNADSDSSHHFILNSVGFATRQVVAGFRYRLMFDMRKSNCSKADHKELNDECHPDPDVELAHCNSTVDVAPWRHETAEANVECAPGPLDNFDVFRRRPPGWSPLRNFNNFAEVKTTQASTASAKEESSEESQERSPSAVTMANPEPALPSVAPTTAAESPFHCPSKPWKQFVPPTTLRPAQEKSPTPLPVVEEGLSDLDLLGKK
What is the function of this protein?
Inhibits papain and ficin (cysteine proteinases) but not trypsin (a serine proteinase).
What are the official names of this protein?
Kininogen.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole.