PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_BURMS
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDAIVAAIRPERGERMVEIGPGLGALTGPVIARLATPGSPLHAVELDRDLIGRLEQRFGELLELHAGDALTFDFGSIARPGDEPSLRIIGNLPYNISSPLLFHLMSFAPVVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELPAVDPAVLGEVVTAAFSQRRKMLRNTLGGYRDLVDFDALGFDLARRAEDIGVDEYVRVAQAVASARASG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_LARHH
Sequence: MTKIERALISVSDKTGILEFARGLAAHGVEILSTGGTAKLLADNNVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLPEHVAKMAEHGIGNIDLVCVNLYPFEATIAKEGCALEDAIENIDIGGPTMVRSAAKNWAHVAIVTDAADYPALLEEMGANAGALSRATRFDLSRKAFTHTAAYDGAISNYLTAVQADQGLAGEPVRTLFPTRLNLQVVKVQDMRYGENPHQSAAFYRDLDPAPGTLAHYRQLQGKELSYNNIADSDAAWEAVKTFDDPACVIVKHANPCGVAVAADPLSAYRLAFATDTTSAFGGIIAFNREVDAATVEAVSAQFLEVLIAPAFTDDAKALIAAKKNVRVLEVPVEAGANRFELKRVGGGLLVQTPDIKNVTLDELKVVTKAQPTRQQLADLLFAWRVAKFVKSNAIVFAAGGQTAGIGAGQMSRVDSTRIAARKAQDAGLSLKNAVAASDAFFPFRDGVDVIAEQGISAIIQPGGSMRDEEVIKAADEHGIAMVFTGNRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DXS_ESCF3
Sequence: MSFDIAKYPTLALVDSPQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALITIEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GLPA_HORSE
Sequence: QTIATGSPPIAGTSDLSTITSAATPTFTTEQDGREQGDGLQLAHDFSQPVITVIILGVMAGIIGIILLLAYVSRRLRKRPPADVPPPASTVPSADAPPPVSEDDETSLTSVETDYPGDSQ
What is the function of this protein?
Glycophorin A is the major intrinsic membrane sialoglycoprotein of the erythrocyte.  Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1.  May be involved in translocation of SLC4A1 to the plasma membrane (By similarity).
What are the official names of this protein?
Glycophorin-A, Glycophorin-HA.
What is the protein family that this protein belongs to?
Belongs to the glycophorin-A family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: A43_LOXLA
Sequence: WIMGHMVNEIYQIDEFVDLGANSIETDITFDDDAIAEYTYHGVPCDCKRWCTKWENVNDFLHGLQRATTPGNSKYRPELVLVVFDLKTGDLSSSTAYKAGNMFAQKLFIHYWNAGNNGGRAYIVLSIPDIDHYAFISGFREAFKNSDHADLLDKVGYDFSGNDDLSATRNALNKGGVKDREHVWQSDGITNCIGRGLGRVRDAVANRDSSNGYINKVYVWTIEKYVSVRDAFDAGVDGIMTNEPDVIVDVLNESAYSSKFRMATYEDNPWETFKYK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LlSicTox-alphaIV3, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RDGC_XANOR
Sequence: MFFRNLTLFRFPTTLDFSQIDTLLPPVQLKPVGPLEMSSRGFISPFGRDEQGVLSHRLEDFLWLTVGGEDKILPGAVVNDLLERKVAEIEEKEGRRPSGKARKRLKDDLIHELLPRAFVKSSRTDAILDLQHGYIAVNSSSRKSGENVMSEIRGALGSFPALPLNAEVAPRAILTGWIAGEPLPEGLSLGEECEMKDPIEGGAVVKCQHQELRGDEIDKHLEAGKQVTKLALVLDDNLSFVLGDDLVIRKLKFLDGALDQLEHSEDDGARAELDARFTLMSAEIRRLFLLLETALKLSKAE
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: G6PI_MESHJ
Sequence: MSLKLEVKTEIKLDYQGFQNQINEFHNRINDKNSPDINFLGWNNFPEVAINPQEIARMRKIVENLHQNSINVLVVIGIGGSYLGAKAALDFILGLGPFENKPEVIFLGNSLSSTDLYQKIEYLKTKNFAINVISKSGSTIEPAITFQILYQFLIDQIGEKLAKTRTFVTTSIKSGELLEIAKSNELEIFEVIESIGGRFSVLSSVGFFPLLFAKINVDEIIQGAIEAHKRYSTSSISQNLAYKYALFRFLMYKNFNYKTEILISYEPFLIYFNEWWKQLFGESEGKNLKGLFPASAIFTTDLHSLGQFIQDGSKNFFQTIIYIKKPKFDLGIKKIVQFNTKINKLSGKTVSEINFQAFLATTLAHSSYGNNPNLVLEIADSSPKTFGHLVMFFEKACAMSAYLLGVNPFDQPGVESYKNELAKNLGWDR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_SHIF8
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: NEP_NATMA
Sequence: MTRDTNSNVGRRSVLKAASALGAFLGLGGVASATPGREPGPKKDEIIVGVSERVSSTEATVESKIPTNAEIVHTNETLGYVAVKFPSNAAEQARENFKRNVLQEDDIEYAEDNATYETLEVPNDPMYGQQYAPQQVNCEGAWAETYGDDDVVISVVDQGIQYDHENLAENMDGSVSDYGYDFVDDDGDPYPVSAGENHGTHVGGIAAGGTNNDTGHAGISNCSMLSARALGDGGGGSLSDIADAIQWSADQGADIINMSLGGGGFSETLDNACQYAYDEGTLLVAAAGNDHGGSVSYPAAYDSVMAVSSLDEGETLSSFSNVGPEIELAAPGGNVLSAVNWDDYDSLSGTSMASPVAAGVAGLALSAHPGLSNDELRDHLHDTAVDIGLSDDEQGYGRVDAELAVTTDPDNGDDDDDDDDDEDDPGDGECGDETNTATADGELSGGWGGNPSDTYSYELSTDNPCHATVTLDGPSSGATFDLFLTLDGRTPTTSDYDRRSYNWGADEEIEVDLDGDEELGILVDRYDGSGSYTLTIEELGS
What is the function of this protein?
Serine protease that hydrolyzes large proteins such as casein and gelatin.  Cleaves preferentially at the carboxyl terminus of Phe, Tyr or Leu (PubMed:10879563).  Is also able to catalyze peptide synthesis under different salt concentrations in the presence of dimethyl sulfoxide (DMSO) (PubMed:21039670).
What are the official names of this protein?
Halolysin-like extracellular serine protease Nep, Subtilisin-like protease Nep.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: P48_NPVAC
Sequence: MCAYRLQYSLRFNIYDRFENVCFEAQLLQDEIDSLCFLFSKYFNQSLIVDSKGLTFFTEFNKCIVSIKSSFENQANNTDNIHNVKNIFSIFLRDEFIKQVPHFRTIMQYLQKYYNPTPAPDVDAIMCQSCKPANKIQCFECKCKYLASSLSTLDAGLQNGWDIFLRPMFGMPLMLYVLLRTDYKNESDIINENNLITQIFVQFFYNLICDKAYSLYTKRDMCVPFVKECKKATVGLRQEDHERVLSILSAQCNGCSTVANGDRLLLPFKNFMIEMGRNTKMKKVNKIASTVLIGFYLRHYLESLPNKAYPVAELELRNVCRFIMSKYSDENINLLIHKLKLIKIDICNVLMTEMIVPETFIRHIITKYQLDNEISLLIELNHDCFNK
What is the function of this protein?
Plays an essential role in the production of budded virions (BVs) as well as in the envelopment of occluded derived virions (ODVs).
What are the official names of this protein?
p48 protein, p45 protein.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p48 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: ANP7_ELEGR
Sequence: AATAATPATAATPATAARA
What is the function of this protein?
Antifreeze proteins lower the blood freezing point.
What are the official names of this protein?
Ice-structuring glycoprotein 7R, ISGP 7R, Antifreeze glycoprotein 7R.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXJ_SYNR3
Sequence: MASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLRQTVRTRLNLEMAATAEMVAIALTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQLQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEASWSQQPLELARLIEGTTEARQLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQEPLFGAGLAAES
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_BRUAB
Sequence: MEHPVFERDPSEKSETERREVPPLLKLALELGPLLVFFFANARGEMLIERFPILGSIGAPIFLATALFMAATVIALAISWSMTRTLPIMPLVSGIVVLVFGALTLWLHNDTFIKMKPTIVNTLFGGILLGGLFFGKSLLGYVFDSAFRLDAEGWRKLTLRWGLFFIFLAIVNEIVWRNFSTDTWVSFKVWGIMPITIVFTLLQMPLIQKHSLTDEENTAS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_PSESM
Sequence: MTLILGIDPGSRITGYGVVRDTGRGCVYVASGCIRTGTGSGELHERLQIVYRGVREVIKTYGPVTMGIEKVFMARNADSALKLGQARGAAIVAGAEEALEIAEYTATQVKQAVAGTGGANKEQVMMMVMHLLKLTQKPQIDASDALAIALCHAHTRSSLIPHGLGTARSRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GLK_NOSS1
Sequence: MTLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHPEKACFAIAGPVVNNTAKLTNLVWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDLLTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPSEGGHADFAPRNELEFQLLKYLLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDPGAAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIENSNFLLNFSQKGRMRPLLAEIPVHIILNQQVGLIGAALCAARL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB2_BRUAB
Sequence: MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSITIVTIAIIWSGYKMAFRHARFMDVVPVLGGALVVGAAAEIASYLLR
What are the official names of this protein?
Type IV secretion system protein virB2.
What is the protein family that this protein belongs to?
Belongs to the PtlA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPP1_NOSS1
Sequence: MTIPIVIEQSGRGERAFDIYSRLLRERIVFLGQQVDSNLANLIVAQLLFLDAEDPEKDIYLYINSPGGSVTAGMGIFDTMKHIRPDVCTICTGLAASMGAFLLSAGAKGKRMSLPHSRIMIHQPLGGAQGQATDIEIQAREILYHKRRLNDYLAEHTGQPIERIAEDTERDFFMSPDEAKDYGLIDQVIDRHAAGSRPVAMVGQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_NITEU
Sequence: MKFSGNWLRKLVDLQYSDEELAHKLTMAGLEVESVAPVAPFFDKVVVAQVVSVQKHANADRLNVCKVDVGTQSDGFLQIVCGAQNVKEGMKTVCALVGARLPELDIRQGKIRGVESLGMLCSAKELGLASDADGLLELPGDTPVGVDFRKYYSLDDCIFTLKLTPNRADCLGMFGIAREVAAITASELDLPEIVFVNPVIEDVLQIRVEEPESCPLYCGRVIKGVATDTAIPLWMSQRLERAGLRMINPVVDIINYAMLETGQPMHAFDLNQINQEICVRFAGENEHLLLLNGERLTLQKDMLVIADSSKPLALAGIMGGSESGVTNTTIDVFLESAFFSPVVISGKSFKLGFTSDSAHRFERGVDFSMTRSVLERATALILEICGGKAGPVTEIGNDLPRREAVRVRQKRIAKILGVDFSVELISEYFQRLQFSYTIAGEMFYVVPPAARFDLVIEEDFIEEIARVHGYDLIPARLPKAPVHMLAEPETGVSPVKRLRQILTAKDYQEVINYTFVDTQWEADFSGNDIPIRLKNPIASHMDVMRSSLFGGLIDNLQFNLNRKQSRVRIFELGSCFSKEGDEEKEVENLAALCSGSAYPEQWGVPDRDIDFYDVKMDIESLFWPRSVYFELALHPALHPGKSARILIDKKPVGWIGELHPRWQSKYHLSQSAILFELRTEALAAELLPAMYPLSKFPPVRRDIAVVVESDVSVASLLETMHLEKDRSISEISLFDLYSGEKLVQGKKSLAFRILLQDSEKTLTDQEIDRAVSQLVGILERKFGATLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPR_NITEU
Sequence: MIKRTLTVSLLSLSLGAMFASAGVMAANEPIQPIKAVTPENADMAELGKMLFFDPRLSKSGFISCNSCHNLSMGGTDNITTSIGHKWQQGPINAPTVLNSSMNLAQFWDGRAKDLKEQAAGPIANPKEMASTHEIAEKVVASMPQYRERFKKVFGSDEVTIDRITTAIAQFEETLVTPGSKFDKWLEGDKNALNQDELEGYNLFKGSGCVQCHNGPAVGGSSYQKMGVFKPYETKNPAAGRMDVTGNEADRNVFKVPTLRNIELTYPYFHDGGAATLEQAVETMGRIQLNREFNKDEVSKIVAFLKTLTGDQPDFKLPILPPSNNDTPRSQPYE
What are the official names of this protein?
Cytochrome c551 peroxidase, Cytochrome c peroxidase.
What are the subcellular locations of this protein?
Periplasm.
Protein: CRCB2_PROMP
Sequence: MELDGFIYILVGSTFGLIVRMFIKYISGKKKIFYSNNILIVNVLASLFLGIFEGLNITNKNLILFIFVGFLGCFSTFSSFIYQLFNLIREKKYLILLIYYAEVILLSFLFFCLGYFITLTFIN
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LCF2_YEAST
Sequence: MAAPDYALTDLIESDPRFESLKTRLAGYTKGSDEYIEELYSQLPLTSYPRYKTFLKKQAVAISNPDNEAGFSSIYRSSLSSENLVSCVDKNLRTAYDHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEANDFVVAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPDMKFVNTLVCMDELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGLPKGVEMSHRNIASGIAFAFSTFRIPPDKRNQQLYDMCFLPLAHIFERMVIAYDLAIGFGIGFLHKPDPTVLVEDLKILKPYAVALVPRILTRFEAGIKNALDKSTVQRNVANTILDSKSARFTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAGVCLSEPFEKDVGSCGAIGISAECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKEVLVENLNRNKKLRKEFLNKINKCTDGLQGFEKLHNIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLYAEGSLVKTEKL
What is the function of this protein?
Activates endogenous medium-chain (MCFA) and long-chain fatty acids (LCFA) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids (PubMed:8206942).  Preferentially acts on C9:0-C13:0 fatty acids although C7:0-C17:0 fatty acids are tolerated (PubMed:8206942).  Is the main if not exclusive MCFA (octanoate, decanoate and laureate) acyl-CoA ligase.  Required for efficient MCFA beta-oxidation inside peroxisomes.  Facilitates the transport of MCFAs into peroxisomes by passive diffusion, by decreasing the intraorganellar MCFA concentration (PubMed:8670886).  Also esterifies LCFAs in the peroxisome matrix.  The LCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane (PubMed:22493507).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 2, Fatty acid activator 2, Long-chain acyl-CoA synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Matrix side. Note=Imported via the peroxisome targeting signal type 1 (PTS1)-dependent protein import pathway.
Protein: DER_PSEU2
Sequence: MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIEEADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKIDNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALREFPRDEDEPEEGVEVEEVAEGQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFERNEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIALNKWDGMTPGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQSVQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKLRYAHLGGANPPLIVIHGNQVEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHKKADKKRRDKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: EI2BL_PYRFU
Sequence: MLPEKVVKILEEMKNEKIRGASWMAKKGAEAFILLSEELDETSLEEGIIELKREILEINPSMASLYNLAMFIPITNDREVVKLRAEEFIKRAEEAKKEIASIGAQLIDSGDVIITHSYSSAVFEILKTAKRRGKQFKVILTESAPDYEGLYLAKALQDESIEVEIITDAQLGLFAKDATLAIVGADTVTKDGYVVNKAGTYLLAISCYESEVPFYVAAETYKFHQKITSKEVELVERPLYREGSRVRNVLFDITPWKFIRGIITELGIILPPRDMI
What is the function of this protein?
Catalyzes the exchange of initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Putative translation initiation factor eIF-2B subunit 2-like, eIF-2B GDP-GTP exchange factor.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: MNME_ALKEH
Sequence: MARTTICALATPPGRGGVAVIRVSGPAVPAIARALAGRLPEPRRAVLARFCDAGGDTLDEGLMLYFPAPRSFTGEDVLELQGHGGEVVVDRLLRRLHALGAHPARPGEFSERAFLNGRMDLTQAEAIADLIAADSEASAQAALRSLEGAFGDAVRELVARVTRLRVQVEAAIDFSDEEIDFLADEAVAGQIGALIDQLQALRDKAGQGRVLRDGMQVVLAGPPNAGKSSLLNALTEDDSAIVTEVPGTTRDLLREHLHIDGMPLHVIDTAGLRDDPDRIEAEGIRRARAAMAEADRVLLIQDIREPPIDPAALALPGDIPLTRVYNKVDLSDEAPGPRRAGDEVAIAVSALTGVGLPALRDHLKSVMGYGEAGSHFSARRRHLDALARAADHLALARRALVEEMAGEIAAEELRLVQHNLGEITGEFTSEDLLGEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG71_SHV21
Sequence: MDLKTTVLHITDSFTDEEMYCLLFLINGCIPRSCNAVNISDLIIETLSKSTQWDICLMQCLYVLRKIGLLLNLFQVTKEAVKQSFFTQPQLETHVLTLVNVNNNLTAKDEKRLCFILDQFFPRNVAAPSVILCVFSNMLCEMHVLECLCQLKKCLKQIGRSDLAKTV
What are the official names of this protein?
Uncharacterized gene 71 protein.
Protein: TRMB_STAAS
Sequence: MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMSLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSNKGSRIYRMEAKFHSQK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PSIE_LISMO
Sequence: MKRLEKISSIVPILLRITLNLALIMVGFTLVAFLIREAFTIFNNIFFLDTDVSYYYMTQDILTFFLYFEFIALIVKYFESHFHFPLRYFIYIGITAIIRFIIVDHSSATSTLILSGAILLLVAALFLANTKMLKREG
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IR75A_DROME
Sequence: MQLVQLANFVLDNLVQSRIGFIVLFHCWQSDESLKFAQQFMKPIHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVGNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTLSDDELIRFLSQENDTHIDSLARFGFHLTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLTATPSLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYTHLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAWKRFFTRHLTFHP
What is the function of this protein?
Odorant receptor for acetic and propionic acid.  Functions as part of an olfactory receptor complex including the ionotropic receptor coreceptor Ir8a.
What are the official names of this protein?
Ionotropic receptor 75a.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: CEC5_MANSE
Sequence: MNFSRVLFFVFACLSAFAMASAAPWNPFKELERAGQRVRDAVISAAAVATVGQAAAIARGG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Bactericidin B-5P, Cecropin-like peptide B-5.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.