PharMolix/UniProtQA huggingface dataset:
Protein: SNA45_LYCMC
Sequence: MKLAILSLFLVFQIGVESKKNGFALDHYGKPWECNLFNVFGPYCNNQCTENKARKGYCCTFTCYCFDLPDDAKILEIGDSRKNYCDVSLTDVLG
What is the function of this protein?
Binds voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin LmNaTx45.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VATC2_RAT
Sequence: MSEFWLISAPGDKENLQALERMNSVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKVHENLLANGVDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKKSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSYVQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYQTSCVALKKGSATYRDHKVKVTPLGNPTRPTAGQNDRESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit C 2, V-ATPase subunit C 2, Vacuolar proton pump subunit C 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
Protein: GCNT3_BHV4
Sequence: MVGWKKKKLCRGHHLWVLGCYMLLAVVSLRLSLRFKCDVDSLDLESRDFQSQHCRDMLYNNLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRPPLTDTYYLNITRDCERFKAQRKFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVKAIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVSWKYLLNTCGTDFPIKTNAEMVLALKMLKGKNSMESEVPSESKKNRWKYHYEVTDTLYPTSKMKDPPPDNLPMFTGNAYFVASRAFVQHVLDNPKSQRLVEWVKDTYSPDEHLWATLQRAPWMPGSVPSHPKYHISDMTAVARLVKWQYHEGDVSMGAPYAPCSGIHRRAICIYGAGDLYWILQNHHLLANKFDPRVDDNVLQCLEEYLRHKAIYGTEL
What is the function of this protein?
Non-essential glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans.  Contributes to the post-translational modifications of structural proteins.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GnT-mucin type, C2GnT-M.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: CDD_SHIB3
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RIMP_PSYA2
Sequence: MKLSTKVTELTNIIAPAVAACDVALWGIEFAPQGNRSLLRIYIEALPEEQAQNKQVTIENCAAVNHQVSGILEVHDPIAGEFILEVSSPGFDRAFFSDEQMHAYVGQTVSLRLIQAIGEGDKKRRKATGTLNSIDGTSLKLTATDGEQFEIALSNIDKANLIYEDA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_AERPE
Sequence: MVSSTAGYRSSALGKLKAFISLTKPRQLALLMLTMYGAYFAGGGSLDPRMLALLTIMGFTSIGGVTAFNMYFDRDIDAIMGRTRRRPLPSGVLNPYEALAGSLALVIAGVLSAAAINTYVALTVIAGLYFDIIAYTQLTKRFTPLSIIFGSIAGSMPALGGWAAAAGSITTGGVLMALIVFLWQPMHVWFLGYYFKEEYSVARIPILPSNGNPRLVSSLIAVSLAGLIAVAWAFALYYGYGFLTAVITTVLAALAISRIGGFARTGERREALKLFKFASPIIAVVFIILPLERTLVYTLLLG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLX2_STAAU
Sequence: MATTKLGNTKSASRAINYAEKRAEEKSGLNCDVDYAKSAFKQTRALYGKEDGIQAHTVIQSFKPGEVTPEQCNQLGLELAEKIAPNHQVAVYTHTDKDHYHNHIVINSVDLETGKKYQSNKKQRDLVKKENDNICREHGLSVTERGIAKMRYTQAEKGIVFDRDEYSWKDELRDLIENAKTHTSNLETFSEHLEEKGVGVKLRGETISYKPENENKWVRGRTLGSEYEKGAIDHEHERHQKQQREPEYADEFKINWDAVEQHTEQLKQRRVERAQETKQAHSKISSRDTRESENQRERAKGNNIRIERGDEGLSR
What is the function of this protein?
This protein is probably required for relaxation complex formation and plasmid mobilization by conjugative plasmids.
What are the official names of this protein?
Protein rlx.
Protein: TAUB_BURMA
Sequence: MAKLCAQQVSVVYASRRGALTALENVSMSVGSGEIVVALGASGCGKSTLLSLLAGFQPPTSGRVSVDGAPVAGPGADRGVVFQDDALMPWLNVIENVAFGLRMQGVGRDARHARARDVLRLVKLAGFEQHRIDEISGGMRQRVGLARALAADPSFLLMDEPLGALDALTREHMQTLLLDVWRATGKGVFLITHSVEEAVLLATELLILSPRPGRIVARHSLDFARRYAHGEPMRSIKSDPRFTEIHLALVEQLMRETEEV
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYY_STAA1
Sequence: MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYGLTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAKELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNYALAPEDKIDGEFTIIRRGKKKYFMVNYQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIA30_PANTR
Sequence: MALVHKLLRGTYFLRKFXKPTSALYPFLGIRFAEYSSSLQKPVASPGKASSQRKTEGDLQGDHQKEVALDITSSEEKPDVSFDKAIRDEAMYHFRHLKDEIVDHWRGPEGHPLHEVLLEQAKVVWQFRGKEDLDKWTVTSDKTIGGRSEVFLKMGKNNQSALLYGTLSSEAPQDGESTRSGYCAMISRIPRGAFERKMSYDWSQFNTLYLRVRGDGRPWMVNIKEDTDFFQRTNQMYSYFMFTRGGPYWQEVKIPFSKFFFSNRGRIRDVQHELPLDKISSIGFTLADKVDGPFFLEIDFIGVFTDPAHTEEFAYENSPELNPRLFK
What is the function of this protein?
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
What are the official names of this protein?
Complex I intermediate-associated protein 30, mitochondrial, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the CIA30 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix. Note=Periferally associated with the matrix face of the mitochondrial inner membrane.
Protein: GYRA_PECCA
Sequence: MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMSVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRMSKIAHELLADLEKETVDFVPNYDGTEQIPDVMPTRIPNLLVNGSSGIAVGMATNIPPHNLTEVVNGCLAYIDDENISLEGLMEHIKGPDFPTAAIINGRRGIEEAYRTGRGKIYIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRIEGISALRDESDKDGMRIVIEIKRDAVGEVVLNNLYSQTQLQTSFGINMVALHQGQPKIMPLKDILVAFVRHRREVVTRRTIFELRKARDRAHILEGLAIALANIDPIIELIRRAASPAEAKASLIAQAWELGSVATMLERAGDDAARPEWLEPEFGIRDGRYYLTEQQAQAILDLRLQKLTGMEHEKLLDEYKELLAEIAELLYILNSPERLMEVIREELEAFKTQYSDERRTEITANTADINIEDLINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREYEEGRHIFMATASGTVKKTALTEFSRHVSGIIAVNLNEGDELIGVDLTDGSDEAMLFSAEGKVVRFSEQAVRSMGRTATGVRGINLQGEDRVVSLIIPRGEGDILTVTQNGFGKRTAVSEYPTKSRATKGVISIKVSERNGKVVGAVQVDAADQIMMITDAGTLVRTRVSEVSIVGRNTQGVTLIRTAEDEHVVGLQRVAEPVEDEELDGVVKVEGEVAEDDDAIDDIDGDDDIAEDDE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STK_SOLTU
Sequence: MAPKTKSRLVDQPPSASSSEEQELVEESQEEEEQQSREEEGEEESGEETEEDEEPKTAHPVVKKPISQKLVQTPQKPQFSSESGSENGSGSDSEAESGNSLPSPSASDFTVKPNVAAKAATPSKPAAKRPQEAQKEKGKKKPKIAEEEEKKSPATPRSLWSDDDQLALLKGILEYKTVKGMEPSADMSAFHEFIRGKLQAEVSKSQISDKVRRLKKKFLTNVKDGEEPVFKKGQDFLIFEHSKRIWGAPGISNGGVKDNVNNTSNGKAKKTVEVKKSSEPKKSAKVSKPKDDEKQKEEEQQVAVKEVVKEDIVKGDQQDFQSKYPRLAASLETMSGLSTMYPNGSSLLKENMSLIATDKAKVLEEKWKKLEDDEAALMVKRLDFIAEHYRLVVDAMRGN
What is the function of this protein?
May act as a transcriptional regulator.  Binds specifically to the B-box motif, a promoter element that is required for the tuber-specific and sucrose inducible expression of the patatin gene.
What are the official names of this protein?
STOREKEEPER protein.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATC_NITOC
Sequence: MTLKTADVEYIAHLARLAIDSEAIPHYKHDLSRILEFVGQMNKVDTTNIEPMAHPLDAIQRLRPDEVTESDQWRTFQSIAPQVEAGVYLIPKVID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: SGRR_SHISS
Sequence: MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
What is the function of this protein?
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ.  Represses its own transcription under both stress and non-stress conditions.  Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
What are the official names of this protein?
HTH-type transcriptional regulator SgrR.
Protein: SYV_LARHH
Sequence: MELAKSFEPGNIENRWYDRWEAAGYFKPSMDTDRPSFCIQLPPPNVTGTLHMGHAFNQTIMDGLTRYYRMKGDNTLWVPGADHAGIATQIVVERQLAEQGVSRHDLGRDTFIGKVWEWKEKSGGTITSQMRRVGCSVDWDKEYFTMDDKMSTAVTEVFVRLYEQGLIYRGKRLVNWDPKLGTAVSDLEVISEEEDGKMWHIRYPVVGSDDVVVVATTRPETLLGDVAVAVNPDDERYRHLVGKQLELPLTGRTIPVIADDYVDAAFGTGFVKITPAHDFNDYQVGKRHNTALINVMSLDATMLAKAQVFGFDGSAQGSIDLPAAYAGLSTADARKAMLADLDAAGLLVDTKPHKLMVPRGDRTGSVIEPLLTDQWFVAMTKVGEGDATGKSITQKAIDAVESGEVRFVPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDEDGKAYVGRTLEEVQAKAPGKTLRRDEDVLDTWFSSALVPFSSLGWPNETPELKAFVPSQVLVTGYEIIFFWVARMIMMTTHFLGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIALPELITKRTTGLRRPEKAPQIVKATEKLFPEGIPAYGTDALRFTMASYASLGRSVNFDFKRAEGYRNFCNKLWNATRFVMMNVEGKDCGQDESLPLEYSFVDKWIISRLQELEAAVTEALDTYRFDMASQLIYEFVWNEYCDWYVELAKVQLANGNEAQQRATRRTLVRVLEVALRLTHPLMPFITEELWQTVAPLANAKKTDSIMVAAWPVADMSKVDAEACGRMTVFKELVNAIRNLRGEMNLGPSVKAPLFVEGPAAYADFLPYARLLGRLSDAAVVEKLPDADAPVAIAGEARLMLKVEIDKAAETARLTKEIGKAESDVEKLTAKLEKPGYVDKAPAQLVERDRAQLADLTDKLAKLKAQLLKLA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC221_ARATH
Sequence: MVKMTLIARVTDGLPLAEGLDDGRDLPDSDMYKQQVKALFKNLSRGQNDASRMSVETGPYVFHYIIEGRVCYLTMCDRSYPKKLAFQYLEDLKNEFERVNGPNIETAARPYAFIKFDTFIQKTKKLYQDTRTQRNIAKLNDELYEVHQIMTRNVQEVLGVGEKLDQVSEMSSRLTSESRIYADKAKDLNRQALIRKWAPVAIVFGVVFLLFWVKNKLW
What is the function of this protein?
V-SNARE involved in vesicle trafficking from the ER to the Golgi complex and required for early secretion (PubMed:21205036).  Involved in endoplasmic reticulum (ER) biogenesis and functions as well as for Golgi-stack integrity (PubMed:21205036).  Essential for gametophytes development (PubMed:21205036).  Involved in cesium Cs(+) accumulation, a non-essential cation (PubMed:23817436).
What are the official names of this protein?
25.3 kDa vesicle transport protein SEC22-1, AtSEC22.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
Protein: KPYK2_SALTY
Sequence: MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCDQNAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSAADGVVAAHEAVNLLRDKGYLVSGDLVIVTQGDVMSTVGSTNTTRILTVE
What is the function of this protein?
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions.  The reaction is critical for the control of metabolic flux in the second part of glycolysis.
What are the official names of this protein?
Pyruvate kinase II, PK-2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: CUER_ECOLI
Sequence: MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCCHHRAG
What is the function of this protein?
Regulates the transcription of the copA and cueO genes.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations.
What are the official names of this protein?
HTH-type transcriptional regulator CueR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRPD
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HIUH2_CAEEL
Sequence: MIKFLLFLAIAAATVISNAELAVPTASISAHVLDISGGSPAGGIQILAFILLNNGWTNIGSQFTQDNGRVDWVSPDFTLIPGTYRLVYITEPYYTAKNVESFYPYVEVVFNIRNATQHYHVPLTLSPWGYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
Probable 5-hydroxyisourate hydrolase ZK697.8, HIU hydrolase, HIUHase, Transthyretin-like protein ZK697.8.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: GUF1_DICDI
Sequence: MFSRLLNRGNGGVNKNITSGLLLRRTTTTTTRLSYINNSPTLSIRSFCSKSTTITSDEKLDLSGYTTDRIRNFSIIAHIDHGKTTLSTKLLSLTGTLPKSIYGSGEDSLVQKEKSEERREQYLDKLQVEKERGITVKAQTCTMKYRNKEDGKDYLLNLIDTPGHVDFSYEVSRSLMACQGALLVVDAVQGVQAQTMANYYLALDSGLEVIPVINKIDLPTADVERVKQELKDAFGFHPDDAVLVSAKTGVGITDILPAVIDRIPPPQEPTKSPKVPFKALLFDSWFDRFRGVICLIKVVDGKVKKGDSIVSAGNKQTYEVFDVGIMHPEQRPAPSLFTGQVGYITPGMKTSKEARVGDTFYMKDFPVEPLPGFQPAKQMVFAGIYPVDSLDYTQLRESFEKLMLTDSSISMTNETSVALGMGFRCGFLGLLHMDVVLQRLEQEYGQVVIATPPTVPYRCLLTDGKEILISNPAGYPSAEHLSKTFEPMVTGHVTLPTEYFGAVVKLCMDSRGILTNQETLEGNRTRITFNFPLGEIVTDFYDNLKRISSGYASLDYEDNGYQESDVAKVRVLLNGEEVDSLSAIVHKSNAQRYSRSLVKRLRKVIDRQMFQVNIQAMVGSDVQARETISAMRKDVTAKCYGGDITRRRKLLDKQKEGKKRMKQMGCVELSQEGFLKLMKSTNDDD
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS5_SYNP6
Sequence: MAEEKDKKQSSRRRNNRRTEKESEWQERVVQIRRVTKVVKGGKKLSFRAIVIVGNERGQVGVGVGKASDVIGAVRKGVADGKKHLVNVPLTRDQSIPHPSTGEGGAAQVLIRPAAPGTGVIAGGAVRTVLELAGVKNVLAKRLGSKSPLNNARAALEALSSLRTFQEVAQSRDIPVEQLY
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HRCA_MYCTA
Sequence: MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: FUT2_PONPY
Sequence: MLVVQMPFSFPVAHFILFVFTVSTIFHIQQRLAKIQAMWELPEQIPVLASTSKALGPSQLRGIWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSTTASRIPWQNYHLNDWMEEKYRHIPGEYVRLTGYPCSWTFYHHLRHEILQEFTLHDHVREEAQKFLRGLQVNGSQPSTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSPIFVVTSNGMAWCQENIDTSHSDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLAGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation.  Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs.  Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition.  Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 2, Alpha(1,2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: ISPF_BURCJ
Sequence: MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.