PharMolix/UniProtQA huggingface dataset:
Protein: CADH5_HUMAN
Sequence: MQRLMMLLATSGACLGLLAVAAVAAAGANPAQRDTHSLLPTHRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNAKYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQKKPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTKKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFILNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQAVVAILLCILTITVITLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPPRPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYGSDPREELLY
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins (By similarity).  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (PubMed:21269602).  This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity).  It associates with alpha-catenin forming a link to the cytoskeleton (PubMed:10861224).  Acts in concert with KRIT1 and PALS1 to establish and maintain correct endothelial cell polarity and vascular lumen (By similarity).  These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (PubMed:20332120).  Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (PubMed:20332120).
What are the official names of this protein?
Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin.
What are the subcellular locations of this protein?
Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.
Protein: HIS7_BACCQ
Sequence: MRESSQIRETTETKIKLSLQLDDGKNVSVRTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALHSKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHAANITLHARILYGSNTHHKIEALFKAFGRALREAVERNANITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACL1_DICDI
Sequence: MDGVEIIAKSIKNSAIEKVFGIVGVPITPIAYELQAQGVGFFGFRNEQSCSYAASIVGYLTGLPGLCMTVSGPGVVHALAGVLNAQSNGWPMILLSSSIDQSLVGKGGFQECKQFESAELYCKKCYYLTEIDHFPEILKDAIETSLSNRPGPVYIQIPADLIKSKCKESPNIREAAGYGTIAIKSVVPDMKLIKDAVQLLSEAKRPLVIGGKGAAYCRSENELLEFIEATKIPFLPSPMGKGLLRDDHPLVVGAARSYALKNADVVLVLGARLNWMFNFGKAPTFSTDVKFIIVDVDENQASKTKNPNVVPEIAIVGDARLSIAEMRKLFIGETDEQPQPPQDSLIKSMKMEESWWSNLNQDIQVKTKSLATLMSEPQNNDQEYLTYHKVFNALRVGGLFQEDTIFVNEGANTMDIGRLCIPQTLPRSRLDAGTLATMGVGVGYSVAAQICFPDRSVVCIQGDSAFGFSAMEMEVAVRYKLPIVFIVLNNNGVYEGLESMSDPKYTSSTESASLHIPPTSLSVDTKYELIMQSFGGTGYSISTISNLLDICKQIKSKQISLPTLLNIKIKPTGTKPKIVH
What is the function of this protein?
Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner.  Involved in the degradation of 3-methyl-branched fatty acids and the shortening of 2-hydroxy long-chain fatty acids.
What are the official names of this protein?
2-hydroxyacyl-CoA lyase 1, 2-hydroxyphytanoyl-CoA lyase, 2-HPCL.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ACOT8_MOUSE
Sequence: MSAPEGLGDAHGDADRGDLSGDLRSVLVTSVLNLEPLDEDLYRGRHYWVPTSQRLFGGQIMGQALVAAAKSVSEDVHVHSLHCYFVRAGDPKVPVLYHVERIRTGASFSVRAVKAVQHGKAIFICQASFQQMQPSPLQHQFSMPSVPPPEDLLDHEALIDQYLRDPNLHKKYRVGLNRVAAQEVPIEIKVVNPPTLTQLQALEPKQMFWVRARGYIGEGDIKMHCCVAAYISDYAFLGTALLPHQSKYKVNFMASLDHSMWFHAPFRADHWMLYECESPWAGGSRGLVHGRLWRRDGVLAVTCAQEGVIRLKPQVSESKL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:11673457).  Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs (PubMed:11673457).  Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains (PubMed:11673457).  Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT) (PubMed:11673457).  Is also able to hydrolyze CoA esters of dicarboxylic acids (PubMed:16141203).  It is involved in the metabolic regulation of peroxisome proliferation (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 8, Acyl-CoA thioesterase 8, Choloyl-coenzyme A thioesterase, Peroxisomal acyl-CoA thioesterase 2, PTE-2, Peroxisomal acyl-coenzyme A thioester hydrolase 1, PTE-1, Peroxisomal long-chain acyl-CoA thioesterase 1.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Peroxisome matrix. Note=Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded.
Protein: FIBER_BPE15
Sequence: MTVSTEVDHNDYTGNGVTTSFPYTFRIFKKSDLVVQVVDLNENITELILDTDYTVTGAGGYTCGDVVLSSPLANGYQISISRELPVTQETDLRNQGKFFAEVHENAFDKLTMLIQQVRSWLSLALRKPSFVANYYDALGNYIRNLRDPSRPQDAATKNYVDNLSEGNNSYADNLFSRTLRVPEKINTLPSSLDRANKIPAFDSNGNAIVIIPQSGSASDVLIELAKPSGSGLVGFSHSNNYNPGMVGEKLQNVVYPTDAPFYAPTDGTSDATTALQSAITHCEGKNAVLCINKSFSVSDSLSISSPLCVFAMNEQCGIVSSAPAGHAAVIFNGDNICWNGGFIRGLNQPSSSTIRQDGVLLNGNDCVLDNVSINGFFAKGLHTSNADGSGVGIRDYGTRNTISKCRVEYNKFGISLEGKDGWVLGNYVSNHYRMSSEAKPWDDTSNYWDGIVGGGEWLGVATGYLIDGNEFEDNGQSGIYAGGNGGIFAKNRITNNHIHGNWNRGIDFGVVQRLANSDVYENIITDNIVHNNRAANIWLAGVRDSIINNNNSWFTDDYRSMFAGNFDACVCLTLADGGEKAAPTGNQVNGNRCKTLESDDQISGFTLNITDTARGNQVRDNVLSPIGEAYIPNPELYAVNNIDIPTEFAFTPQLIGGSGVTLGNSSGKLTANGNVFSLSLSISAQSVSSPSGSLTIGYIPGLSGTSVRHHNVRTEFYNNLNTTMQRAQPYVNIGDSADQLRVYRLADGLSKDDLLEYFMSNSDLRMVGDIEIEPYNFSRSVTVVGHSFCTSDVMSTELNRLLGTDIYNFARGGASDVEVAMSQEAITRQYAPVGGSIPASGSVALTPTEVGIFWNGATGKCIFGGIDGTFSTTLVNAGTGETQLVFTRDSAGSAVSVSTTATFAMRPYTRFNTNTIPAGRKHSLHRDDIYIVWGGRNSTDYTRYVSELHTMVANMHTQRFVICPEFPYDTETTGTTGATNLAALNNNLKADFPDNYCQISGVDLLQNFKSKYNPAYAGDVTDIANGITPRSLREDNLHPSETLQPNGLYIGAKVNADFIAQFIKSKGWGG
What is the function of this protein?
Structural component of the short non-contractile tail (PubMed:16452981).  The tail comprises six spikes that mediate primary attachment to the host cell lipopolysaccharides (LPS) and display endorhamnosidase enzymatic activity, hydrolyzing the linkage between rhamnose and galactose of the O-antigen polysaccharide.  Digestion of the LPS brings the capsid near the cell outer membrane (PubMed:20709082, PubMed:4633001).
What are the official names of this protein?
Tail spike protein, TSP, Endorhamnosidase, Gene product 20, gp20.
What are the subcellular locations of this protein?
Virion.
Protein: CCME_SHELP
Sequence: MNARRKKRLALATALIGGVAAIASLLLYALNSNLNLFYTPTEIVHGKKDTGVKPEIGQRIRVGGMVTVGSLVRDPESLHVEFAVHDAAGGEVMVTYDDLLPDLFREGQGIVAQGVLIEGGKLEATEVLAKHDENYMPPEVAEAMGQTHEKLEYDSTQKTGY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ACEK_SALPC
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWETLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKND_CHLT2
Sequence: MQRYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRKRFLREAKIAADLIHPGIVPVYSICSDGEAVYYTMPYIEGFSLKSLLKSVWQKEVLSKELEEKTSVKSFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGLFGEVVIVDWGAAIFKHAKELKLEQDDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTLAFPYRRKKGRKLSYRDVVLPPIEMSPYREIPPSLSQIAMKAIAINPADRFSSIQELRQALQPYLQGDPEWTVKATLMAKEKSCWKYYDPILLSRYFPVLASSPAQWYNFMLSEVEISASTRVEYTVTKSAVHEGMGILFLPSKEAERGEFYCGYGLWFSVQNHELTVSLIKNGIEIQKKSQEMISQQYRFAILIEKSDNRIAVFVEQALFILHIDYLPSLGNRLGVIIQDLQGMSNIAISESIGALRVSCLAVPDAFLSEKLYDQAAIFYRKIRDSFPGRKESYEAQFRLGVTLLTQIEEQGGDLTQALSSFDYLHGGAGAPLEYLGKALVYQRNGSFVEEIRCLLFALKRYSQHPEIPRLEDHLCFRLYDSLHKHRSEALVFMLLILWIAPEKISVREEKRFLRIIYHKQQATLFCQVDKAPLQFRSSKMELFLSFWTGFSLFLPELFRRAGELRDYQALADIFYVAGVSGNREAFMQFSTALANVSDEITFPESLHNQKVAELMFFVKGVEALRNKDYQKAKKLLWKTPFTLQLYALDIFHIQAFLDEEIESFIDLLQAIYDPASEEERDHILVYIIQTHLWNRDLERAYKLLNDRFPLDEELAEYSEAFILWGCYLALTGDRVAVKAHFSRCRYKYGKSALIGKCVDGDIFDYLDNLVWWEKKMTLFQSYFLLRCLNESPRRYEKYRQAYLSMENNFFD
What is the function of this protein?
Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth (Probable).  Autophosphorylates and also phosphorylates Pkn1 (PubMed:14500499).
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: LEP_MYCLE
Sequence: MTETTDSVPEPPSDADQLQPKVSICGLDMPAEVSETAAEAAIGVSEPKKRSALWEFAILAVIAIGLYYVMLTFVARPYLIPSESMEPTLHGCSGCVGDRIMVDKITYRFSSPQPGDVIVFKGPPSWNTMYKSIRSNNIVLRSVQNALSFVGFVPPDENDLVKRVIAVGGQTVQCRSDTGLTVNGKPLKEPYLRPVTMNADLSFSPCLGSEFGPVTVPQGRLWVMGDNRIHSADSRYHCNSTDVVNGLSCTGDPNSGTVPVSNVIGKARVVVWPPSRWGGVGSVNSQQGQ
What are the official names of this protein?
Probable signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: TRM5_AJECG
Sequence: MEEAATLQSLSISSSSPFPNNSSPVVTAANTISTSESDMFRAPVNRMMRTLDRSFFKKTVPLSAATIFDKQSIGSIKSELLQSQDLLLANRIIPVRAAREGPLENVTDHWYGRKDGKQDGRKCLLLREGIKADDVTTWSPTIQKLVEAKSVEVRPFNLLLDYDYFTYTHFNLREQYLPYKYLLGEILRDKHPQARTVINKTDDVGSHSEFRTFSYEVLAGEDDMLVTVHEQDCEYSFDYSKVYWNTRLATEHERMVSRFKKGEAVCDVMAGVGPFSIPAGKKQVFVWANDLNPYGYECLERGAAKNKVREFVKAHNMNGRDFIRFATERLYQGNPRTVVHRTKVPKAERENSPIRQRKPKAFDTEYLTCPRTFDHFVMNLPATAIEFLDAFRGLYAGMQELFEPYTDRKLPLIHVYCFSTNSEDEALERKDICERISERLGFKITPEDEGRELEIRSVRLVSPTKKMFCASFRLPAEVAFKKA
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: AMPA_RHIL3
Sequence: MSIKLEISFSKSAKLNGGLAILLKTAEADSAAGAETVDPAGVIVKAARIARYSAKSMNGLDIVVPEGAPVDRIVVIGLGKAAELTAHDWLKAGGAAASRIKNTDKAAVFIDVPGLTTSPRAAADFALGMLLRAYSFDTYKTKKGDEEEKPAKSVKVTIVTADPAGAKKAFSDSEAIAGGVNLARDLVNEPPNVLGPVEFAAKAKELEKLGVEVEILTEREMRRLGMGALLGVAQGSVRPPRLAVMQWKGGKGKDRPVAFIGKGVVFDTGGISIKPAAGMEDMKGDMGGAAAVTGLMHVLASRKAAVNAVGIIGLVENMPDGNAQRPGDIVTSMSGQTIEVINTDAEGRLVLCDALWYCNDRFKPQFMINLATLTGAIIVALGNVHAGLFSNDDQLSAQLTAAGLSSNEKLWRMPLGRDYDKLIDSKFADMKNTGGRQAGSITAAHFLKRFVQDTPWAHLDIAGTAMGSPQDEINQSWGSGFGVRLLDELVRAHYES
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_BACC1
Sequence: MGKLYVFDHPLIQHKITYIRDKNTGTKDFRELVDEVASLMAFEITRDLPLKDIEIETPVSKATTKVIAGKKLGLIPILRAGLGMVDGILKLIPAAKVGHVGLYRDPKTLQPVEYYVKLPTDVEERDFIVLDPMLATGGSAAEAINSLKKRGAKQIKLMCIVAAPEGVKVVQEEHPDVDIYVAALDEKLNDHGYVVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NODS_RHIFR
Sequence: MRSSRSDIRRCFGCRFPKVLSPTHSKSGARPAIHGKLAPYCKRLTVIDVVPRAIARTRQRMKESSHINWIVADVRQFSTQQLFDLIVVAEVLYYLEDVAAIRTAVHNLVSMLAPSGHMVFGSAIDANCRRWGHVAGTETVIAMLNETLIEVEQLYCRGASVNEDCLLSRFQKSTT
What is the function of this protein?
SAM-utilizing methyltransferase involved in nod factor synthesis.
What are the official names of this protein?
Nodulation protein S.
What is the protein family that this protein belongs to?
Belongs to the NodS family.
Protein: LIFR_MOUSE
Sequence: MAAYSWWRQPSWMVDNKRSRMTPNLPWLLSALTLLHLTMHANGLKRGVQDLKCTTNNMRVWDCTWPAPLGVSPGTVKDICIKDRFHSCHPLETTNVKIPALSPGDHEVTINYLNGFQSKFTLNEKDVSLIPETPEILDLSADFFTSSLLLKWNDRGSALPHPSNATWEIKVLQNPRTEPVALVLLNTMLSGKDTVQHWNWTSDLPLQCATHSVSIRWHIDSPHFSGYKEWSDWSPLKNISWIRNTETNVFPQDKVVLAGSNMTICCMSPTKVLSGQIGNTLRPLIHLYGQTVAIHILNIPVSENSGTNIIFITDDDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSWNPGRITGLVGPRNTEYTLFESISGKSAVFHRIEGLTNETYRLGVQMHPGQEIHNFTLTGRNPLGQAQSAVVINVTERVAPHDPTSLKVKDINSTVVTFSWYLPGNFTKINLLCQIEICKANSKKEVRNATIRGAEDSTYHVAVDKLNPYTAYTFRVRCSSKTFWKWSRWSDEKRHLTTEATPSKGPDTWREWSSDGKNLIVYWKPLPINEANGKILSYNVSCSLNEETQSVLEIFDPQHRAEIQLSKNDYIISVVARNSAGSSPPSKIASMEIPNDDITVEQAVGLGNRIFLTWRHDPNMTCDYVIKWCNSSRSEPCLLDWRKVPSNSTETVIESDQFQPGVRYNFYLYGCTNQGYQLLRSIIGYVEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGFLRGYLFYFQKGERDTPKTRSLEPHHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTHGGLGPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSNALKTLEMNPCTPNNVEVLESRSIVPKIEDTEIISPVAERPGERSEVDPENHVVVSYCPPIIEEEITNPAADEVGGASQVVYIDVQSMYQPQAKAEEEQDVDPVVVAGYKPQMRLPISPAVEDTAAEDEEGKTAGYRPQANVNTWNLVSPDSPRSTDSNNEVVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND
What is the function of this protein?
Signal-transducing molecule.  May have a common pathway with IL6ST.  The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
What are the official names of this protein?
Leukemia inhibitory factor receptor, LIF receptor, LIF-R, D-factor/LIF receptor.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: ASSY_ALIF1
Sequence: MSKKVEVNKVVVAYSGGLDTSVIIPWLKENYNCEVIAFVADVGQGEEELEGIEAKAIASGATECYVVDLKEEMVSEYIFPTLKTGALYEGKYLLGTSMARPIIAKAQVEVARNVGADALCHGCTGKGNDQIRFEGAFAALAPDLHVIAPWREWDLVSREECLDYLAERNIPCTASLTKIYSRDANAWHISTEGGVLEETWNAPNDDCWAWTVDPEQAPNESETISLKVEKGAVVAVDGKAMTPYEVVVYLNEKGAKHGVGRIDIVENRLVGMKSRGCYETPGGTIINEALRAVEQLVLDKTSFEFREELGIKASHLVYDGRWFTPLCKSILAASEELAKDVNGEVVIKLYKGHATVIQKRSDNSLYSEEFATFGADEVYDQSHAEGFIRLYSLSSRIRALNSK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP4Z1_HUMAN
Sequence: MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKVC
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the in-chain oxidation of fatty acids (PubMed:19090726, PubMed:29018033).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Hydroxylates lauric and myristic acids predominantly at the omega-4 and omega-2 positions, respectively (PubMed:19090726, PubMed:29018033).  Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA).  Displays an absolute stereoselectivity in the epoxidation of arachidonic acid producing the 14(S),15(R)-epoxyeicosatrienoic acid (EET) enantiomer (PubMed:29018033).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:19090726, PubMed:29018033).
What are the official names of this protein?
Cytochrome P450 4Z1, CYPIVZ1, Laurate 7-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Protein: SYN_SALTY
Sequence: MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFNAVLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAILERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y970_MYCTU
Sequence: MIHDLMLRWVVTGLFVLTAAECGLAIIAKRRPWTLIVNHGLHFAMAVAMAVMAWPWGARVPTTGPAVFFLLAAVWFGATAVVAVRGTATRGLYGYHGLMMLATAWMYAAMNPRLLPVRSCTEYATEPDGSMPAMDMTAMNMPPNSGSPIWFSAVNWIGTVGFAVAAVFWACRFVMERRQEATQSRLPGSIGQAMMAAGMAMLFFAMLFPV
What are the official names of this protein?
Uncharacterized protein Rv0970.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROB_MYCGI
Sequence: MTEPVTVDVRTDPPYPVIIGRGLLGDLGRVLDGRHKVAILHQPTLTQTAEAIRTHLSEKGIDAHRIEIPDAEGGKELPVVGFIWQVLGRIGVGRKDAIVSLGGGAATDVAGFAAATWLRGIDIVHVPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPAAVLIDLATLESLPRNEIVAGMAEIVKAGFIADPVILDMIEADPEAALDPSGAVLPELIRRAVVVKAEVVAADEKESQLREILNYGHTLAHAIERRERYQWRHGAAVSVGLVFAAELGRLAGRLDDDTTERHRAILTSLGLPVTYDADALPQLMESMLGDKKTRAGVLRFVVLDGLAKPGRLEGPDPSLLAAAYAEVARD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_BORDL
Sequence: MYKDIDSHQRDSRTDGHQDGFKKNPNFRFFKKKTCKFCDMDRVPDYKEFDFLKKFITEQGKILPRRITGTSAKHQRRLALEIKKARYMALLPFVKK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYRH_CUTAK
Sequence: MPERYNRVLLKLSGEVFGGGGIGVDADVVSAKAREIAEIANSGVQVAVVVGGGNFFRGAELQQHGMQRDRADYMGMLGTVMNCLALQDFCEKAGVDTRVQTAITMGQVAEPYIPRKAERHMEKGRVVIFGAGSGMPYFSTDTVAAQRALEIGADALLMGKQGVDGVYDSDPKTNPNAHKFDELTYDEFLSRDLKVADATAVAMARDNDLTMVFFNLEMPGNISRVINGEDIGTTVHR
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PEDPA
Sequence: MASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEGLADVEMHDNTAAIVEVNSETDFVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGTLNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGGKIAALVLLEGADEETAKDVAMHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLDDQEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP19_BRUME
Sequence: MGISKASLLSLAAAGIVLAGCQSSRLGNLDNVSPPPPPAPVNAVPAGTVQKGNLDSPTQFPNAPSTDMSAQSGTQVASLPPASAPDLTPGAVAGVWNASLGGQSCKIATPQTKYGQGYRAGPLRCPGELANLASWAVNGKQLVLYDANGGTVASLYSSGQGRFDGQTTGGQAVTLSR
What are the official names of this protein?
Outer membrane lipoprotein omp19, 18 kDa immunoreactive antigen, 19 kDa OMP, Minor outer membrane protein omp19.
What is the protein family that this protein belongs to?
Belongs to the rhizobiaceae omp19 lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.