PharMolix/UniProtQA huggingface dataset:
Protein: SC13_MESMA
Sequence: MNYLVMISFALLLMKGVESVRDAYIAKPENCVYHCAGNEGCNKLCTDNGAESGYCQWGGRYGNACWCIKLPDDVPIRVPGKCHR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin is active against mammals (By similarity).
What are the official names of this protein?
Toxin BmKaTx13, Alpha-neurotoxin Tx13, BmKalphaTx13.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMAP_MOUSE
Sequence: MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDEDDSPDAESPDDSDSDSESEKEESAEELHAAEHPDDTEDPKSKKDAKSNYKMMFVKSSGS
What are the official names of this protein?
Small acidic protein, Sid 2057.
What is the protein family that this protein belongs to?
Belongs to the SMAP family.
Protein: GPMA_ALTMD
Sequence: MYKLVLIRHGESQWNLENRFTGWHDVDLTDTGVAQAKTAGQLLKDAGFTFDQAYTSVLLRAIKTLNIALEEMGQHYLPVERHWRLNERHYGALTGLDKAETAAKHGEEQVKIWRRSFDIPPPAVEDDSEHFPGHDPRYNNVDADILPRGESLKLTIERVLPYWHDVIRPDIQAGKRVIIAAHGNSLRALVKYLDGMSDEEVLGLNIPTGVPLVYELDENLKPISKEYLGDADAIKAMMDAVAKQGQAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: 5DNU_SALPA
Sequence: MKQSHFFAHLSRMKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGQLNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMAPDELRDIFAPLIDENAWSEEEQAIVKQADALCAYLKCLEELSAGNNEFGLAKTRLEKTLELRRSQEMDYFMAVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_LEPIC
Sequence: MKVRTSVKKICSSCKVIRRKGVIRVICTNPKHKQRQA
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TATA_ANOFW
Sequence: MLSNIGVPGLILILVIALVIFGPKKLPEIGRAFGETLREFKKSTKGLRDEVLEELDENKK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL5_JANSC
Sequence: MLDTANYTPRLKAAFSETIKAAMKEEFGYKNDMQIPRLEKIVLNIGSGAESVRDTKKAKSAQEDLTAIAGQHAVVTKAKKSIAGFRLREEHPVGAKVTLRGDRMYDFLDRLTTIAMPRIRDFRGVKPSFDGRGNFAMGMKEHIVFPEINFDKIDVAWGMDIIIVTTANTDAEAKSLLAHFNMPFNA
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SODC_YARLI
Sequence: MVKAVAVLRGDSKVSGTVTFEQDSESGPVTVTYDIKGNDPNAERGFHVHEFGDNTNGCTSAGPHFNPFKKNHGGPTDSERHVGDLGNVKTDSEGVAKGVLKDSLLKLTGDNSIVGRTVVIHGGEDDLGKGGHADSLKTGNAGPRPACGVIGLTA
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYN_RAT
Sequence: MGCVQCKDKEAAKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance.  Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain.  Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.  Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin).  Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT.  Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage.  Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6.  Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein.  Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation.  Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation.  Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts.  CSK maintains LCK and FYN in an inactive form.  Promotes CD28-induced phosphorylation of VAV1.  In mast cells, phosphorylates CLNK after activation of immunoglobulin epsilon receptor signaling (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane. Note=Present and active in lipid rafts. Palmitoylation is crucial for proper trafficking (By similarity).
Protein: ADDB_STRP3
Sequence: MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQQDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKSLSKEVIEVCFPKRIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFDNKLKQAIYHTNQESFFQQIYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQEKNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQITPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNRYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: Y993_HAES1
Sequence: MSLQFNSIALLLVSLILLGVLGNNSSITISATILLLMQQTFLAKYIPFTEKYGVNIGIIILTIGVLSPIVSGKVQLPNWTALIHWKMFLAMAVGVLVAWFGGRGVNLMGTQPSLLTGLLVGTILGVAFLGGVPVGPLIAAGILSLFIGKTG
What are the official names of this protein?
UPF0756 membrane protein HS_0993.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TTDB_SHIFL
Sequence: MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELKRPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGKGGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEFGPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK
What are the official names of this protein?
L(+)-tartrate dehydratase subunit beta, L-TTD beta.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: MSRA_CLOPE
Sequence: MKKIILAGGCFWGVEEFLSRINGVVSTEVGYANGRTENPTYEDICTKNTYFAEVCLVNYDENIISLKELLAKFWTIIDPTSLNKQGNDVGSQYRTGIYYVDSSDLEDILNSKEELQKSYSKKIVTEVKPLENYYKAEEYHQKYLKKNPNGYCHIKLD
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CXB6_MOUSE
Sequence: MDWGTLHTVIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETARKFIRGEKRNEFKDLEDIKRQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTVFMISASVICMLLNVAELCYLLLKLCFRRSKRTQAQRNHPNHALKESKQNEMNELISDSGQNAITSFPS
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-6 protein, Connexin-30, Cx30.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: BASS_ECOLI
Sequence: MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI
What is the function of this protein?
Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation.
What are the official names of this protein?
Sensor protein BasS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL1_METLZ
Sequence: MVERTQIINAVTAAITQAPERKFQESIDITINLKHVDMAQPKNRIDETILLPQAIGVKKIAVLGKGDIVSQARNAGVDLIIGPDEIERLGGVPREARKMAGQYDFFLAETAVMPLVGRWLGQRLGPRGKMPQPIPPTQDITPIVERLRNSVKIRSKDRLNMSVKVGNTGMTVEEVSENIDAVVKRVVGRLESGELNIRSVYVKTTMGPAVKVM
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL19_PARUW
Sequence: MIMSRSAIIEKLQNEQMKKDITPFRIGDTVRVHIRIIEGDKERTQVFAGTVIARKGQGLSETFSVHRVAYGEGMERVFMLHSPRIAKIEVIKEGDVRRSKLYYLRGTSGKASKVKARLGARRSSNAVTKQIVSAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SYGB_HAMD5
Sequence: MTHQTFLVEIGTEELPPKSLRSLVESFAFYLTQELNKAHLDHGEVTWFATPRRLAVKVACLSTIQKDQKIEKRGPAIAQAYDVDGNPTKAATAWARSCGISLDQAKSLVTDKGEWLLYSWVLPGKSASSLLAEKVKIALSQLPISKLMSWGIHEAKFVRPVHTVTLLLGDELISGIIFGVNSNRKILGHRFMGEPSFIIEHADQYPQILLEKGKVMADFFLRKTQIKTDIEKAAEKIGAIADISDNLLEEVTSLVEWPVVHTAQFEKKFLEVPSEALVHTMKNDQKYFPVYNKSGQLMPYFIFVANILSQDPPQLIFGNEKVIRPRFADAQFFFETDLKQSLEERLPSLKTILFQKELGTLYEKVQRVQALSGWIASQIGANVEYSIKAGLLSKSDLMTNMVCEFPETQGIMGMHYARYHHEPDEVARAIYEQYQPRFSGDNLPSTLVACSVAIADKMDTLTGIFGINQLPKGDKDPFGLRRAALGVLRIIVEKNLPLDLQTLISEAVRLYGNKLKNSNLIDQIIEFMLGRFRSWYQEAGHGIDSIQAVLARRPTKPADFNARIQAVTYFRTMNEARALCASNKRVSNILSQSLDIPKNSIDTGLLKEPAEIELAQNILELEKKLAPFFVAGLYKDALLELVALREPLDIFFKQVMVMVPDQDLRLNRLALLNKLRALFLRVADISFLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS51_HUMAN
Sequence: MAAAAAAGPSPGSGPGDSPEGPEGEAPERRRKAHGMLKLYYGLSEGEAAGRPAGPDPLDPTDLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKFISATDTIRKMKNDFRKMEDEMDRLATNMAVITDFSARISATLQDRHERITKLAGVHALLRKLQFLFELPSRLTKCVELGAYGQAVRYQGRAQAVLQQYQHLPSFRAIQDDCQVITARLAQQLRQRFREGGSGAPEQAECVELLLALGEPAEELCEEFLAHARGRLEKELRNLEAELGPSPPAPDVLEFTDHGGSGFVGGLCQVAAAYQELFAAQGPAGAEKLAAFARQLGSRYFALVERRLAQEQGGGDNSLLVRALDRFHRRLRAPGALLAAAGLADAATEIVERVARERLGHHLQGLRAAFLGCLTDVRQALAAPRVAGKEGPGLAELLANVASSILSHIKASLAAVHLFTAKEVSFSNKPYFRGEFCSQGVREGLIVGFVHSMCQTAQSFCDSPGEKGGATPPALLLLLSRLCLDYETATISYILTLTDEQFLVQDQFPVTPVSTLCAEARETARRLLTHYVKVQGLVISQMLRKSVETRDWLSTLEPRNVRAVMKRVVEDTTAIDVQVGLLYEEGVRKAQSSDSSKRTFSVYSSSRQQGRYAPSYTPSAPMDTNLLSNIQKLFSERIDVFSPVEFNKVSVLTGIIKISLKTLLECVRLRTFGRFGLQQVQVDCHFLQLYLWRFVADEELVHLLLDEVVASAALRCPDPVPMEPSVVEVICERG
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy.  VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960).  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 51 homolog, Another new gene 2 protein, Protein fat-free homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS51 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex (PubMed:25799061).
Protein: RPGFL_PONPY
Sequence: MEGPEGLGRKQACLAMLLHFLDTYQGLLQEEEGAGHIIKDLYLLIMKDESLYQGLREDTLRLHQLVETVELKIPEENQPPSKQVKPLFRHFRRIDSCLQTRVAFRGSDEIFCRVYMPDHSYVTIRSRLSASVQDILGSVTEKLQYSEEPAGREDSLILVAVSSSGEKVLLQPTEDCVFTALGINSHLFACTRDSYEALVPLPEEIQVSPGDTEIHRVEPEDVANHLTAFHWELFRCVHELEFVDYVFHGERGRRETANLELLLQRCSEVTHWVATEVLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMGLDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNHKSYREVISKMKPPVIPFVPLILKDLTFLHEGSKTLVDGLVNIEKLHSVAEKVRTIRKYRSRPLYLDMEASPHHLQTKAYVRQFQVIDNQNLLFELSYKLEANSQ
What is the function of this protein?
Probable guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Rap guanine nucleotide exchange factor-like 1.
Protein: SPLA_STAA3
Sequence: MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: UREF1_BRUA2
Sequence: MTIITPITNDPTTALLRLMAWLSPVFPVGSFSYSHGLERAVHDGLVVDAAGLQDWLQWLVRRGSGWNDAVLCAESWRCAMKGEDLHEIAELAEALAGSRERHMETMLQGGAFFAAARSWPCEIFDRLPPDCAYPVAVGAVAGGHGVPLAQALAAFLQAFCINLLQASIRLSVTGQSGVTAIMAALEPVLGETAARAALSSMEDLGSATFIADIMAMKHETQHSRLFRS
What is the function of this protein?
Disruption of the ure1 gene cluster suggests that it protects brucellae during their passage through the stomach.  The major route of infection in human brucellosis is oral.
What are the official names of this protein?
Urease accessory protein UreF 1.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_RAT
Sequence: MALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCAFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: RS7_RICCK
Sequence: MSRRHAAGKRVILPDMKYNSILLSRFINNLMKEGKKALAEKIVYSAFNKIEKKHRVDPYQIFNNAMHNVKPHLEVTSVRVGGANYQVPTHVDESRGYALASRWIINAALKRSEKMMIDKLAEELFEASNNRGVAIKKKEDTHKMAEANKAFSHFSPKKMK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL35_METNO
Sequence: MPKLKTKSGAKKRFKITGTGKVLYAQAGKRHGMIKRTTKQIRNLRGTTTLFEGDAANVKKFFLPNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: O1614_CONAE
Sequence: MKLTCVLIIAVLFLTACQLTTGEQKDHALRSTDKNSKLTRQCTPVGGYCSRHHHCCSNHCIKSIGRCVAH
What are the official names of this protein?
Conotoxin ArMKLT2-0111.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SELO_ECOLI
Sequence: MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLWFSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation).  Cannot use GTP, CTP or UTP as cosubstrate.  AMPylates SucA at 'Thr-405' and GrxA on 'Tyr-13'.  Regulates protein S-glutathionylation levels probably by AMPylation of deglutathionylation enzymes such as GrxA.  Probably involved in redox homeostasis.
What are the official names of this protein?
Protein adenylyltransferase SelO, Selenoprotein O homolog, SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: UVRC_BARQU
Sequence: MKKNISYGKHKTFPSKLNGLEKQHSLSKNERDNFPFLSNIPWDNANQGSDKNQLKGAKLIQEFVKHLPHKPGVYRMFDENGNVLYIGKARNLKKRVSNYTCEQRHNNRITRMIRATYHMEFVVTHTETEALLLEANLIKRLHPRFNVLLRDDKSFPYIIITENHRAPALYKHRGARTRKAHYFGPFASSSAVTQTINVLQRAFLLRTCTDSVLENRTRPCLLYQIKRCSAPCTHEINENDYRELVRGAKAFLSGKSQSVKNDMIQAMHKAAEDLDFEQAAVYRDRLSALSHIQSHQGINPQTIEEADVFAIAQKGGITCIQVFFFRMRQNWGNRSYFPKADPSFSRSEILASFLAQFYDDKPLPKLILLSEEIEEKTLLAEAFSLKANRKIFLSLPKQGERKTLVNHAYINAYEALGHKLAETATHTKLLQGIAEVFQLPQTPHRIEVYDNSHLMGTNAVGAMIVADQMGFLKNQYRKFNIRSTDITPGDDFGMMKEVIKRRFSRLIKEHGLPHESNSIKGEDEDCFSIWPNLILIDGGEGQINSVHTILSELKLDDFITVVGIAKGADRGAGHERFFIKGKTPFTLPPHDPILYFLQRLRDEAHRFAIKTHRIKRKKATLKNPLDEIKNIGSTRKRALLHHFGSAKIVASASLEDLTKVTGISVTIAQKIHNHFNEK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.