PharMolix/UniProtQA huggingface dataset:
Protein: DXS_ACIBY
Sequence: MPHMLYTEIPTQRPVTPLLDAIDHPQQLRQLEHSQLLQVADELRQYILYAAGQSGGHFGANLGVVELTVALHYCFNTPNDRLVWDVGHQAYPHKILTGRREQITTIRAKNGLAAFPAREESVFDTFGVGHSSTAISAGLGMSLARRYQKDPCEVVCIVGDGAMTAGMAFEAMNDAVAHDADLIVVLNDNDMSISCSTGGFAKHLAAIWEKGHLVNVNEHGEAYIQPHPKWTYNSRLHQSATDAADNLFKAIGFDYFGPFDGHDVTQLVQVFNALKKRKGPRLVHVYTKKGKGFAPAEADPITYHAIGKINAASGGKTPPKYSDVFGEWLCDEAAQDERLLAITPAMCEGSGMVKFAKQFPQRFFDVAIAEQHAVTLAAGMACEGLKPVVAIYSTFLQRGYDQLIHDVALQNLDVTFGIDRAGLVGEDGPTHAGAYDYAYMRTVPNMVIMAPKDENECRQMLHTAYAYNGPAAVRYPRGAGVGVEIQKEMTVLELGKAEIVAEIKANSDEQITVLAFGSRVMVALEAAEQFAQKHDVSVCIVNMRFVKPLDEQMIRDLAEHTHLFVTVEEHAIMGGAGSAVNEFMAQEQIVKPIINLGLPDSFLHQATHNQMLQDCGLDAKGILNSIERAWLKVNQVV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RSMH_ENTHR
Sequence: MTETFQHYTVMLKETVDGLNIKPDGIYVDCTLGGAGHSEYLLSQLNTNGHLYAFDQDQKAIDHAKVRLAPYIEKGMVTFIKANFRELEAKIKEHVPQVDGILYDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYDVVNEYSYNELVKIFFRYGEEKFSKQIAREIERVRKIHPIQTTGELVEIIKDVIPAPARRKGGHPAKRIFQAIRIAVNDELGAEEASLEQAIRLLKINGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVVPEEFQPELKLINRKPILPSEEELSENNRSRSAKLRIAEKIRVKEE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGR1_SOLLC
Sequence: MGTLTTSLVVPSKLNNEQQSSIFIHKTRRKCKKNQSIVPVARLFGPAIFEASKLKVLFLGVDEEKHPGKLPRTYTLTHSDITSKLTLAISQTINNSQLQGWYNRLQRDEVVAEWKKVKGKMSLHVHCHISGGHFMLDLFARLRNYIFCKELPVVLKAFVHGDENLLRNYPELQEALVWVYFHSNIQEFNKVECWGPLRDATSPSSSSGGVGGVKSTSFTSNSNKKWELPKPCEEACACCFPPVSVMPWLSSNLDGVGEENGTIQQGLQEQQS
What is the function of this protein?
Required to trigger chlorophyll degradation during leaf senescence and fruit ripening (PubMed:18359841, Ref. 3, PubMed:23406468).  Binds directly PSY1 to regulate the accumulation of lycopene and beta-carotene in the maturing fruits (PubMed:23406468).
What are the official names of this protein?
Protein STAY-GREEN 1, chloroplastic, LeSGR1, SlSGR1, Protein GREEN FLESH.
What is the protein family that this protein belongs to?
Belongs to the staygreen family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOC_XANOP
Sequence: MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSGEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPLVASVTDIWPGVNWFEREAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAAGEVGRSETAK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CRCB3_METAC
Sequence: MIGTGGFIGASLRYTISSRVPKIQNIPAGTLTVNLLGSIVLALLTFSSEPESVVYLVNIGMLGSFTTFSTFAYETFRLLEDGQNISFFLNIFLNVMLCLLGVSIAYLALML
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 3.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCOP_RHOCA
Sequence: MSKKPTTKKEVQTTGHQWDGIEELNTPLPRWWLWTFYATIIWGVAYSIAMPAWPIFSDKATPGLLGSSTRADVEKDIAKFAEMNKAVEEKLVATDLTAIAADPELVTYTRNAGAAVFRTWCAQCHGAGAGGNTGFPSLLDGDWLHGGAIETIYTNVKHGIRDPLDPDTLLVANMPAHLTDELLEPAQIDEVVQYVLQISGQPADEVKATAGQQIFAENCASCHGEDAKGLVEMGAPNLTDGIWLYGGDVATLTSTIQYGRGGVMPSWSWAADGAKPRLSEAQIRAVASYVHSLGGGQ
What is the function of this protein?
C-type cytochrome.  Part of the cbb3-type cytochrome c oxidase complex.  CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit.  From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place.  The complex also functions as a proton pump.
What are the official names of this protein?
Cbb3-type cytochrome c oxidase subunit CcoP, Cbb3-Cox subunit CcoP, C-type cytochrome CcoP, Cyt c(P), Cytochrome c oxidase subunit III.
What is the protein family that this protein belongs to?
Belongs to the CcoP / FixP family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ISPF_SHEFN
Sequence: MNIRIGHGFDVHKFGGDSPLVLGGVTVPYDSGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDANFAGADSRVLLKHCYQLALQKQFVLGNLDVTIIAQAPKMAPHIEAIRQCLSADLQTDIDNINVKATTTENLGFTGRKEGIAVEAVVLMKSQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PGK_XYLFA
Sequence: MSIVRMTDLALSGKRVLIRQDLNVPIDQGRITSEQRIIASLPTIRVALERGAAVMVTSHLGRPKEGVWSEEDSLAPVAKRLSQLLGIEVPLRRDWVDGVQVAPGQLVLLENCRMNVGEAENDEALARKYAALCDVFVMDAFGTAHRAQASTHGVICCAAIAAGGPLLMAELDALSRGLEHPVKPLLAIVGGSKVSTKLELLSNLVNNVEQLITGGGIANTFLAAAGYSIGKSLYEGDLIETAREIITAAKARGAEIPLPTDVVVAKQFLPGVTATVKTVDAIVADDLILDIGPQTARHYAALIETAATVVWNGPVGVFEFDAFSKGTEVLARAVAASSAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLEFLEGKTLPAVAALQARSG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_BORT9
Sequence: MQFEVKDLINKIKKDGLEEAEKLANEIILNAKRDAEAIVLKAESDAKDLKMQAEAEANEYKRYSLEASRQAVRDLIIGTEKNIKSLFKTALKDSVSRVYDDNFLRDLIIKVVDIWSKNDKIDIMLNESDFSNLLSVLRAKIGNRLDDAIEIKPFKGISKGFTIQQRDGNLYYDFTSETVADILFEYLNPRFKEVIKLI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: LEAD_ADE05
Sequence: MRADREELDLPPPIGGVAIDVVKVEVPATGRTLVLAFVKTCAVLAAVHGLYILHEVDLTTAHKEAEWEFEPLAWRVWLVVFYFGCLSLTVWLLEGSYGGSDHHAARAQSPDVRARRSELDDNIAQMGAVHGLELPRRQVLRRRGT
What are the official names of this protein?
I-leader protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae leader protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Might be loosely associated with the nuclear membrane.
Protein: ATPE_BACCA
Sequence: MKTIHVSVVTPDGPVYEDDVEMVSVKAKSGELGILPGHIRLVAPLEISAARLKKGGKTQYIAVSGGFLEVRPDKVTILAQAAERAEDIDVLRAKARKSGRTPLQSQQDDIDFKRAELALKRAMNRLSVAEMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCL8_PIG
Sequence: MQVSAALLCLLLTTAAFSTQVLAQPDSVSIPITCCFGLVNGKIPFKKLESYTRITNSQCPQEAVIFKTKADKEVCADPQQKWVQNSMKLLDQKSQTPKP
What is the function of this protein?
Chemotactic factor that attracts monocytes.  This protein can bind heparin.
What are the official names of this protein?
C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: REGQ_BPP22
Sequence: MRLESVAKFHSPKSPMMSDSPRATASDSLSGTDVMAAMGMAQSQAGFGMAAFCGKHELSQNDKQKAINYLMQFAHKVSGKYPGVAKLEGNTKAKVLQVLATFAYADYCRSAATPGARCRDCHGTGRAVDIAKTEQWGRVVEKVCGRCKGVGYSKVPASAAYRAITMLIPNLTQPTWSRTVKPLYDALVVQCHKEESIADNILNAVTR
What is the function of this protein?
Mediates the switch from middle to viral late gene expression by associating with host RNA polymerase (RNAP) so that the latter can read without pausing and through transcription terminators preceding late genes.  Competes with host factor sigma 70 for binding to RPOB, the beta-subunit of host RNAP.  To join the elongation complex, binds a specific DNA Q-binding element (QBE) and interacts with RNAP that is paused during early elongation.  Participates in the lysis-lysogeny decision by activating the expression of the late lytic genes.
What are the official names of this protein?
Antitermination protein Q.
What is the protein family that this protein belongs to?
Belongs to the phage antitermination Q type 2 family.
Protein: RF1_XANAC
Sequence: MTPTLRRKLQALAERREELQHLLSDPDVVGNNDTFRTLSRELSQLEPVAVALEEEARAKADLATAEALRNDPEMRELAEEEIAAAQARLEQLDAQLASLLVPRDPRDDGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDSPGEHGGYKEVVARVVGRGAYSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADDVEEITINPADLKVDTFRSSGAGGQHVNKTESAIRITHVPSGVVVECQTERSQHANRDKAMKRLKAQLLDTERSKAAAAEAQTRKLQVGSGDRSQRIRTYSFPQGRITDHRVEGLTLYDLPNIIEGDLDALIGRLLHEHQADELARLSDSP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_XYLFM
Sequence: MGVESVRCPLHFTKMQGAGNDFVVLDLRDGTPPPDAALVAWLADRHFGIGCDQVIAIEPPRGVGVVAAYRIWNADGSAAQQCGNGARCVAAWLVRDGSLADEHFLIDSPVQAHSVRCIGKDEYAVEMGLPVFEPERIPLSGFPNACAEYVLSLQGEVLRCGAVSMGNPHAVVEVDLIDVAPVERIGPLLQQHVAFPESVNVGFVQVIDPGLVRLRVYERGAGETLACGSGACAAAVVLMQRGRVGRDVRVVLPGGTLRVQWPVSGGPVTLSGPARCVFDGVWYG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_STRT1
Sequence: MSDYLSVTSLTKYLKMKFDRDPYLERVYLTGQVSNYRRRPSHQYFSLKDEGAVIQATIWAGVFKKIGFDLEEGMKINVVGRVQIYEPSGSYSLIIEKAEPDGIGALALQFEQLRKKLTAEGYFDDRHKQPLPNFVKKIGVITSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGDGAAQEIVENIQKANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQSIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPISKADTLAWIRERQNRAYQACLRRIQYNQERLAKLSQSVVFRQPERLYDGYLQKLDHLTTRLETFMSQDFERKQKSAEFLRQRLHGLNLSTRVKNYQDRRESLQRLLVTTTKNTINGNRVRLEKAQDALLSLDTSRIVARGYAIVNKNDKPLTTIKDITEGEQLTIQMRDGQLEVEVKNVNEKNI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KN8A_ORYSJ
Sequence: MPVSTRASAAGGQPWSSAAPAPASAPGRGGARREILTNHHHHGLKEKMRALTLFYEQHKQQLASSQGGGARGRRSIQYAVGEVGGDENGRNAEEEDDVGRKRHDAVPAAVLRENMAPPEERAPPPPPAPPPKSSHVVVFSRQADPTEKENVSHGGIATMSCPIKKAAPALPAPAARKLSLGGGMAARLKTAGEAGAGNGDAAGSRIMVFVRLRPMSRKEKDAGSRSCVKIVNKKDVYLTEFASETDYLRLKRVRGRHFCFDSSFPDTTTQAEVYSTTTSDLVEGVLQGRNGTVFCYGATGAGKTYTMLGTMESPGVMVLAIKDLFTKVRQRSHDGNHSIQLSYLEVYNETVRDLLSPGRPLLLREDKQGTVAAGLTHYRAYSTDEVMKLLQQGNQNRTTEPTRVNETSSRSHAILQVIVEYRSIDGGSIVTRVGKLSLIDLAGSERALATDQRTQRSIEGANINRSLLALSSCINALVEGKKHIPYRNSKLTQLLKDSLGGSCNTVMIANISPSNLSFGETQNTLHWADRAKEIKTKALTTANEEVLRVTDSETDQAKLVLELQKENSELRQQLARQQQKLLTVQAQTLASNASPQQSPAPSAQISTPCSTQRKVKRSILAGNCFNTPDSKRPAAENAQVRDLQRKVKAMEAEIEKMKKEHLLQLKQKDEFIRDLINRKTSNVPEAATCERRVATRASVRKAQKDAAAAGELRSPSHRFTSPVPTAKKRTFWDIGGNSPSTLAVNGRKTRSHVAAETPKGTSMLLQPGFARQRAIH
What are the official names of this protein?
Kinesin-like protein KIN-8A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-8 subfamily.
Protein: CLPP1_THEVB
Sequence: MLQSRYDHPLSAILRSPALNLPPTHANIVPMVVEQSGRGERAFDIYSRLLRERIIFLGGGAGDRRGIDDAVADSIVAQLLFLDAEDPEKDIYLYINSPGGSVTAGMAIYDTMKHIRPDVCTLCFGLAASMGAFLLSGGTPGKRMALPNARIMIHQPLGGAQGQAVDIEIQAREILYHKRKLNELLSQHTGQPIERIEADTERDFFMSAEEAKAYGLIDQVVTRQTLLSP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_PIG
Sequence: MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDMNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAARDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
What is the function of this protein?
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in PAF inactivation.  Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner (By similarity).  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome.  Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate.  Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates.  During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules.  Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors.  May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.  Required for dynein recruitment to microtubule plus ends and BICD2-bound cargos.  May modulate the Reelin pathway through interaction of the PAF-AH (I) catalytic dimer with VLDLR (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha, Lissencephaly-1 protein, LIS-1, PAF acetylhydrolase 45 kDa subunit, PAF-AH 45 kDa subunit, PAF-AH alpha, PAFAH alpha.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus membrane. Note=Localizes to the plus end of microtubules and to the centrosome. May localize to the nuclear membrane. Redistributes to axons during neuronal development. Also localizes to the microtubules of the manchette in elongating spermatids and to the meiotic spindle in spermatocytes.
Protein: CP4V2_PONAB
Sequence: MAGLWLGLVWQKLLLWGAASAVSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKRDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSRQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHVNQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSQMIFQRIKMPWLWLDLWYLMFKEGWEHEKGLKILHTFTNNVIAERANEMNADEDCRGVGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGCNPEVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRDADEP
What is the function of this protein?
A cytochrome P450 monooxygenase involved in fatty acid metabolism in the eye.  Catalyzes the omega-hydroxylation of polyunsaturated fatty acids (PUFAs) docosahexaenoate (DHA) and its precursor eicosapentaenoate (EPA), and may contribute to the homeostasis of these retinal PUFAs.  Omega hydroxylates saturated fatty acids such as laurate, myristate and palmitate, the catalytic efficiency decreasing in the following order: myristate > laurate > palmitate (C14>C12>C16).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Cytochrome P450 4V2, Docosahexaenoic acid omega-hydroxylase CYP4V2, Long-chain fatty acid omega-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NBL1_XENLA
Sequence: MTIWFLIGFLLPVAIFAAPPPINRLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPIDSVWDVVTLECPGNEEFPRVDKLVEKILQCSCQACGKELSQEGAMFNVYLNTAEDSPAESLGHHQHRPPAREDDSPAQSHREGESEE
What is the function of this protein?
May act as a tumor suppressor (By similarity).  Cytokine that has an axial patterning activity.  Acts like bone morpho-genetic protein (BMP) antagonist in embryonic explants.  Blocks the bmp2 activity.
What are the official names of this protein?
Neuroblastoma suppressor of tumorigenicity 1.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
Protein: O162_CONBU
Sequence: MKLTCVLIIAVLFLTAITADDSRDKQVYRAVGLIDKMRRIRASEGCRKKGDRCGTHLCCPGLRCGSGRAGGACRPPYN
What are the official names of this protein?
Conotoxin Bu2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_BRYMA
Sequence: MAPKTETKAGAGFKAGVKDYRLTYYTPDYQVKDTDILAAFRMTPQPGVPPEECGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDLEPVKGEENQYIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRISVAYAKTFQGPPHGIEVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKSQAETGEIKGHYLNATAATCEAMLQRAQCAKELGVPIIMHDYLTGGWTANTSLAHYCRDHGLLLHIHRAMHAVIDRQKNHGMHFRVLAKSLRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDDFIEKDRARGIYFTQDWVLLPGVMPVASGGIHVWHMPALVEIFGDDACLQFGGGTLGHPWGNAPGAAANRIACEACVQARNEGRHLAREGGDVIRAACKWSPELAAACEVWKEIKFEFETIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCC_BURP6
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.