PharMolix/UniProtQA huggingface dataset:
Protein: CCL4_CANLF
Sequence: MKLCVTVLSLLVLVAAFCSPALSAPMGSDPPTACCFSYTLRKIPRNFVADYFETSSLCSQPAVVFQTRRGRQVCANPSEPWVQEYMDDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2137_ERWT9
Sequence: MDHRLLEIVACPVCHGKLYYNKEQQELICKPDGLAYPVQDGIPVLLEVEARALTLEESHP
What are the official names of this protein?
UPF0434 protein ETA_21370.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: 1FEH2_WHEAT
Sequence: MAQAWAFLLPVLVLGSYVTSLFFPSYISNPLCGGDGGRSLFLCAQAPKDQDPSPAVSTMYKTAFHFQPAKNWMNDPSGPMYFNGIYHEFYQYNLNGPIFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPIIIYTGGDIDQHQAQNIAFPKNRSDPYLREWIKAPNNPVLRPDEPGMNSIEFRDPTTGWIGPDGLWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPLYSHNGSNMWECPDFFAVLPGNNAGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLQRDAFVPDNVVDDRRLWLRIDYGTFYASKSFFDSNKNRRIIWGWSRETDSPSDDLEKGWAGLHTIPRTIWLAGDGKQLLQWPVEEIESLRTNEISHQGIELNKGDLFEIKEVDAFQADVEIDFELASIDDADPFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSQEKYMVLMCSDLRRSSLRPDLEKPAYGGFFEFDLEKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADVGRAHIYAFNNGSATVRVPQLSAWTMRKAQVNVEKGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans, but not beta-(2,1)-linkages in branched fructans.  Has low activity against beta-(2,6)-linked fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis.
What are the official names of this protein?
Fructan 1-exohydrolase w2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: RS17E_METM7
Sequence: MGRIRQTFIKRTGEELIEKFADKFTSDFEENKKAVEEVAMISTKTLRNRVAGYVTAKVKKMNA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: NHBA_NEIMB
Sequence: MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQGQGAPSAQGSQDMAAVSEENTGNGGAVTADNPKNEDEVAQNDMPQNAAGTDSSTPNHTPDPNMLAGNMENQATDAGESSQPANQPDMANAADGMQGDDPSAGGQNAGNTAAQGANQAGNNQAAGSSDPIPASNPAPANGGSNFGRVDLANGVLIDGPSQNITLTHCKGDSCSGNNFLDEEVQLKSEFEKLSDADKISNYKKDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGSYALRVQGEPAKGEMLAGAAVYNGEVLHFHTENGRPYPTRGRFAAKVDFGSKSVDGIIDSGDDLHMGTQKFKAAIDGNGFKGTWTENGSGDVSGKFYGPAGEEVAGKYSYRPTDAEKGGFGVFAGKKEQD
What is the function of this protein?
[C2 fragment] Localizes to host mitochondria when applied to the apical side of human endothelial cell layers, where it induces production of reactive oxygen species which lead to increased permeability of host endothelial cells.  The C1 fragment (which lacks the first 14 residues of C2) does not have this effect.  It is not known if this occurs during Neisseria infections.
What are the official names of this protein?
Neisserial heparin binding antigen, NHBA, Genome-derived Neisseria antigen 2132, GNA2132.
What is the protein family that this protein belongs to?
Belongs to the NHBA family.
Protein: CP51A_ASPFU
Sequence: MVPMLWLTAYMAVAVLTAILLNVVYQLFFRLWNRTEPPMVFHWVPYLGSTISYGIDPYKFFFACREKYGDIFTFILLGQKTTVYLGVQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVVYDCPNSKLMEQKKFIKYGLTQSALESHVPLIEKEVLDYLRDSPNFQGSSGRVDISAAMAEITIFTAARALQGQEVRSKLTAEFADLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMRSIYVDIITQRRLDGEKDSQKSDMIWNLMNCTYKNGQQVPDKEIAHMMITLLMAGQHSSSSISAWIMLRLASQPKVLEELYQEQLANLGPAGPDGSLPPLQYKDLDKLPFHQHVIRETLRIHSSIHSIMRKVKSPLPVPGTPYMIPPGRVLLASPGVTALSDEHFPNAGCWDPHRWENQATKEQENDKVVDYGYGAVSKGTSSPYLPFGAGRHRCIGEKFAYVNLGVILATIVRHLRLFNVDGKKGVPETDYSSLFSGPMKPSIIGWEKRSKNTSK
What is the function of this protein?
As a target of azole drugs, plays a crucial role in azole susceptibility.
What are the official names of this protein?
Sterol 14-alpha demethylase cyp51A, Cytochrome P450 monooxygenase 51A, Ergosterol biosynthesis protein 11A.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MURQ_ECO55
Sequence: MQLEKMITEGSNTASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: QUEA_BUCAI
Sequence: MQLSDFSFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFNIIDEINSGDLIILNNTQVIPARFFGKKESGGKVEVLVEKILGINNILASIKNSKNINIGSKIFFGYKDKIKGSVVDCKNSFFEIFFHDNIDSAIDIINNIGEIPLPPYIKRFRNKLDVDLYQTVYKKKTGSIAAPTAGLHFDLPLLEALHNKGVDIDYITLHIGSGTFQPIRRVQIEEHIMHSESVEVSSSVIQKIKSCKKKGGRIIAVGTSTLRALESAYHSSEWSDSQDFISDTNIFIYPGYKHNIVDALITNFHFPESTLIMLVCSFLGYKNTMNAYNTAIVNKYSFFSYGDAMYITHNKLAPYENFII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROP2_GALME
Sequence: EIRLPEPFRFPSPTVPKPIDIDPILPHPWSPRQTYPIIARRS
What is the function of this protein?
Antimicrobial protein.  Has antibacterial activity against the Gram-positive bacterium M. luteus (MIC=8. 6 uM).  Lacks antibacterial activity against the Gram-positive bacteria B. circulans, L. monocytogenes, S. aureus, and S. lutea, and the Gram-negative bacteria E. coli D31, E. coli ATCC 25922, and S. typhimurium.  Lacks antifungal activity against S. cerevisiae, P. pastoris, Z. marxianus, C. albicans, C. fructus, C. wickerhamii, A. niger, F. oxysporum, and T. harizianum.
What are the official names of this protein?
Proline-rich antimicrobial peptide 2.
What are the subcellular locations of this protein?
Secreted.
Protein: CI131_MOUSE
Sequence: MGLLQGQLTHALACRHCSSITCLHSPGNLAILVLFMVWQIRRWWQLRGWQQLQPWCSGDKMTQGKGLQLLYHLAFFDCLWKQKSEEEEKEEKECLSLNPLKPYHLSKDTPIGNGFSTAPPHPSCRSEGRPRATETQEQVLIQSPSPSRSFPTFQTLTNLPVRSKRASGSSPQQTKLQLFSGLPSLYNESLKTIFLSSDGPSPLKLSICPSVFLNKVPFPPAYNLLLPCYHSSTYYPTPEAHILEDLEEIAPGSQLVQSPPSPPIPLVSSNLKPLLKGYKRIIPDTEVHTQWFTQNKEVPSVSENQGLYPQPELQKFRSSTFLYSSEVWRKRPGDLRLHQHNPELPFAFLLYPFNPQEVLDRFEMPWRNMKQNEHPKASETAMPTASPLPISLTECQRVNPTGDLSQVKTLCQTTVQKENLQIYELPISAPCQLTVPVTEGTGPPGTPPGYEAQWGILAYKGIPQASDPLMPASCHPSGSLSKVKNVNPKERLSAPKDVRENLGYREHPHVSKSPVSAPSPPLDTLSDYQRENPPEDGSGFKPQWECKETSGSPWASETPTLDFHVGFYEATPMCVPLGSEAQLKGTPSTENLCVYADIVSSPSLPSVSLPDFAIMGPQRILLESKALWETKEQKKHLWTSDSSCPHKTPLAPFIGPKRINTVDDVPRSEATGKNTDNTKKCSSSEPPFLNLNPSPALVQQPLRVSPIENPLKSKAWCGHIQRKNNFLASELPAQSLSQHLLEPSPEGVLSDVEPAGGFMKNKNHCVSASPVWECSPSPNSVLKFHISEPSGDQCNCTPKESVAEWTKDSWANELPGSSFFSALSQEPHSETELVCRNVLEREASQGPNPPAVNPPQPTAWPIQPGLSEAKAEAPSSQGEAVSEVSDHPVIHAWQWSRQLKLRLNKLQQSPTFKSPGSHHSFSSSPVLNLTLESWGPSSCSQQMHPLSLHPCSSSSHPPKVQRAEALPVQAPHCLHSSSQPQAQASGRAEQRSQKSKRLKRKAMVQIPSPGLGHVKADENCSGMGEPSDTGLLVSGKRQDKTLVLLSTQKRGSSRKSKAEKCGRTARLGSPTNTRENNPAQACRPAEASMPRFSRKFEHKAQSSPHSALAQQLLPNAAGPQDRPRTGLVAGETQNPCPFKCCPWIPTKQQLSSLSQEAPPTRGFQKLIDKFLGVHRPLPTKSSP
What are the official names of this protein?
Uncharacterized protein C9orf131 homolog.
Protein: HIS7_METPE
Sequence: MRESIVERRTSETDIVLKIGLDRTEPHQITISTGIPFFDHMVQAMSRHGGFDLNITAKGDLEVDSHHTIEDIGIVLGTALQQALGDGRGIKRFGYAIIPMDEALAEAVLDCGGRGYLVFKGTFGNSTVGGIDTSLFEHFFYSLCIHAGITAHIRFSGQNDHHTAEAIFKAFGIALGQAVTIIPESNQIPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_ACET2
Sequence: MTLSKSKLLFERAKKVIPGGVNSPVRAFGAVGGYPPFIKKAKGARIYDADGNEYIDYVGSWGPMILGHSHPRVLEAVSKTMVDGLSFGAATELEVQMAELITELVPSVEMVRMVNSGTEAVMSAIRVARGYTKREKIIKFAGCYHGHADSMLVKVGSGAMTNGIPNSGGVTAGAAKDTLIARYNDIDSVKLLFEQNKGNIAAVIVEPVAANMGVVPPKDNFLEELRKLCDKEEALLIFDEVITGFRLAIGGAQQYFGVNADLVTYGKIIGGGMPVGAYGGRREIMECVAPVGDVYQAGTLSGNPIAMSAGIATLRELYENPGIFENINRLGQRLSEGLGKITKYTVKAVGSLVCVFMTEEEVNDYDSAVKSDTGLFGRYFNHLLNNGIYIAPSQFEAMFVSNAHTDKDIDETLEKVSLFFARKSPPA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_BRASB
Sequence: MTVHFPFQNSYAALPDNFFARVAPTPVAAPRLIKLNRPLAAELGLNPAELETAEGAEILAGKTVPEGAEPIAMAYAGHQFGHFVPQLGDGRAVLLGEVVDKNGVRRDIQLKGSGPTPFSRRGDGRAALGPVLREYIVSEAMAALGIPTTRSLAAVVTGEQVYRGIALPGAVLTRVATSHIRVGTFQYFAARQDVEAVRRLADHVISRHYPDLAGTERPYHALLDAVIARQAKLIADWLLVGFIHGVMNTDNTSVSGETIDYGPCAFMDGYDPKQVFSSIDEFGRYAFANQPRIALWNLTRLAECLLPLFGDDKDQAIKEAEAALDGFAAQFTDAHQAGLRRKLGLFTQVEGDQPLAQALFDAMAAVKADFTLTFRRLSDAAGSGDDAPVRALFEDPTGLDEWLPRWRQRLADEPQTAAERAAAMRQVNPAFIPRNHRIEAVITAAVENDDYAPFEELHAVLARPYDDQPAFSAYAEPPQPDERVLQTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL11_METJA
Sequence: MAKEVVEVLVTGGRATAGPPLGPAIGPLGVNVMQVVKEINEKTKDYEGMQVPVKVIVDTETRKFEIEVGIPPTTALIKKELGIETAAHEPRHEVVGNLTLEQVIKIAKMKKDAMLSYTLKNAVKEVLGTCGSMGVTVEGKDPKEVQKEIDAGVYDEYFKEE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DMSA_HALSA
Sequence: MSDTDLNATRRDVLKSGAVAAVGLSGGGLLSTLQEADDSDTAGDAVTSFLGEDQVVKTACSPNCRGKCPLDVFVRDGQIKKVEQQVPAAKTFKRGCTLGMTHLQRVYNADRLKYPMKRTSWSPDDPQPDQRGADAQFERIAWDDALDLVADGIQRAKREYGPRSLLWHSGSGDGGITGYRRLKELVGGLQDDFTYGIDTNVGQGFNRVTGEGGVFMPPTNTADDWVNAETIIIWGSDIFASQFQMDAEWILDAKRNGAKLVVVDPVYTNTAEKADLWLPIKPGKDTHLALAMMQYIFEHDHYDEAFLRSRTNAPALVRADDGTLLDPASVTATPPEDGIVVFNTETGSPEVVPAETNGPFALFGEWTIDGTTVHTGLTALREQASSYPPQAVADTAGLAAADIETAADWLATRGPGGIMPSYGVGRYLYGHVFGQTYATLLALTGDYGRHGNIHAQHPSYDGSYLETGDWNDPDGAAGVDTYGYNRVLDLLANGDPVQTKFMYGMNSNMLGNQFPERDRWLDAMSNLDTVVWADIYHTPTTRQADIILPAAHWFETEDLLTTYTHPNLSYRTKAHDPLWEARDDYYIMAGLAQRLGHGDKFPDDKHDVLDRFVKNDDRLSWDALRETGTVATDETPTVAYTDEFGTESGRITVYDDDAPVEEGPALPDDGVSLEVPKPLEARTADDWAHADEYPLLFMQKHSKWRIHSQWANVPWLREINTEPQLDIHPKDATRRGIDDGEYVRVHNDRGSVVVRAKYNDGIQPGLVNTDQGWWARDFVDGHLQDLISAETAKVGRTFAFYDCRVEVTRAADEHQSNEYTQHNPRGSSGTATDGDSS
What is the function of this protein?
Dimethyl sulfoxide (DMSO) reductase catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) during anaerobic respiration; it can also use trimethylamine N-oxide (TMAO) as terminal electron acceptor.  Required for anaerobic respiration on DMSO and TMAO; subunit A is proposed to be catalytically active.
What are the official names of this protein?
Putative dimethyl sulfoxide reductase catalytic subunit A, DMSO reductase subunit A.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RBFA_BURM1
Sequence: MSRKRTSPNRNVQIADQIQRDLSELIMREVKDPRIGIVTIQSVELTPDYAHAKVYFTTLTGDPAATQQALNHASGHLHNLLFKRLHIHTVPTLHFHYDQTIEKAVAMSRLIDEANATRAKDDDEADAPAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_SALNS
Sequence: MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQADLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAANAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFPLYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: IVD_SOLTU
Sequence: MHKLFVARSVKSALFRIKNHQKPQFAAFSTSLLFDDTQKQFKESVAQFAQENIAPHAEKIDRTNYFPQDVNLWKLMGNFNLLGITVPEEYGGLGLGYLYHCIAMEEISRASGSVGLSYGAHTNLCINQLVRNGTHEQKQKYLPKLISGEHVGALAMSEPNAGSDVVSMKCKADRVEGGYVLNGNKMWCTNGPTAQTLVVYAKTDVTAGSKGITAFIIEKGMTGFSTAQKLDKLGMRGSDTCELVFENCFVPEENVLGQVGRGVYVLMSGLDLERLVLASGPVGIMQACLDVVLPYVKQREQFGRPIGEFQFVQGKVADMYTSMQSSRSYLYSVARECDSGTINTKDCAGVILSAAERATQVALQAIQCLGGNGYVNEYPTGRFLRDAKLYEIGAGTSEIRRMIIGRELFKEQ
What is the function of this protein?
Involved in the catabolism of amino acids.  Uses isovaleryl-CoA as substrate.  Minor activity detected with 2-methylpalmitoyl-CoA or 2-methylbutanoyl-CoA, but no activity with short- and medium-straight chain acyl-CoA esters or with 2-methylhexanoyl-CoA.
What are the official names of this protein?
Isovaleryl-CoA dehydrogenase, mitochondrial, IVD, Isovaleryl-CoA dehydrogenase 2, St-IVD2.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LIPI_HUMAN
Sequence: MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT
What is the function of this protein?
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid.  Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
What are the official names of this protein?
Lipase member I, LIPI, Cancer/testis antigen 17, CT17, LPD lipase, Membrane-associated phosphatidic acid-selective phospholipase A1-beta, mPA-PLA1 beta.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane. Secreted. Note=May associate with lipid draft. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane. Secreted. Note=May associate with lipid draft.
Protein: NGBR_HUMAN
Sequence: MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK
What is the function of this protein?
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Both subunits contribute to enzymatic activity, i. e.  condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490, PubMed:32817466).  Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length (PubMed:32817466).  Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.  Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit NUS1, Cis-prenyltransferase subunit NgBR, Nogo-B receptor, NgBR, Nuclear undecaprenyl pyrophosphate synthase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.
Protein: PME_PRUPE
Sequence: MPYLLMASHNPLPAGKQLLLLVLLCAFFSSSFIPFASCSITDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYKENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV
What is the function of this protein?
May have roles in the deposition of pectin in developing tissues and in the wall loosening and cell separation that occurs in cell expansion, fruit ripening and abscission.
What are the official names of this protein?
Pectinesterase/pectinesterase inhibitor PPE8B.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: K2C73_HUMAN
Sequence: MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR
What is the function of this protein?
Has a role in hair formation.  Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).
What are the official names of this protein?
Keratin, type II cytoskeletal 73, Cytokeratin-73, CK-73, Keratin-73, K73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RL111_PLAVT
Sequence: MRGTLATALLLVASCRIAAESNQINPQQASHHVGTTLNKLFTKSSPRRFLRDNREQRVALALTAANESRTIENAVTSAVHGITDASTTTAATRDAARDILNQHAFPKEGIRPQFDLNLPPSETSALLTGASNIPQRNHAFSSITSGIAVSSSRTSNQRTAKTQANLDMSHQGTVRKTLSKTQFKNPAASKSTKRRKKARIIPPFVVNKVDTLYREHLTAKSLEFDPTIKETEAMLKLYVESTVDPLPVSTVHFNHFRYFKDQDLTLLKEKLGTTLESALSTLAALNLPPGMLKAIERPFVWYASLARWRAMYCDFFEFLNANSNKIATSLPNVEFFGGETSSTVRDQLLATLKEEMKTRTKTRRNGKIMNDLKVVLAKYNVEEEIKAAIRGLGEQFLKRDHEIIPLQRHSRRSPASQSRSNNQRTGLTPYGLQIPGPERDSFRHIESNKHA
What is the function of this protein?
Secreted effector that acts as an elicitor that induces cell death in host plant cells.
What are the official names of this protein?
Secreted RxLR effector protein 111.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Localizes to speckle-like structures within the nucleus.
Protein: PRS54_MOUSE
Sequence: MAEMRGMLLMLLYISHSSSAICGIQKATIADKLKENLVSSTEFPWVVSIQDKQYTHLAFGCILSEFWILSTASALQHRPEVIAVVGISNMDPRKTDHREYSVNTIIPHENFDNVSMGNNIALLKTESAMHFNDLVQAICFLGKKLHKPPALKNCWVAGWNPTSATGNHMTMSILRRISVKDIEVCPLRRHQKTECASHTKEPNNVCLGEPGSPMMCQAKKLDLWILRGLLAYGGDSCPGLFLYTSVADYSDWITAKTRKAGPSLSSLHLWEKLVFELPFHESNIALTTNSFSIHTYAEWPHSYSQGQRMSTKSNKQKDAGQNFRVNRQPETSGPSKVAIQPMYYDYYGGEAGEGGAVAGQNRLHWSQERILMSFVLVFLGSGV
What are the official names of this protein?
Inactive serine protease 54, Plasma kallikrein-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADK_SHIB3
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.