PharMolix/UniProtQA huggingface dataset:
Protein: COX10_ASPFU
Sequence: MIYLRSSLLRSGLARDPARLCSQCFSRLSPSRRPVAVRSFFSSSRLRAGIADHESTPSTVQKTYFSANRTADGLLASLSAVNSSPRSIADNALSQGAASSESITSQSTSQELPHRRRKRLKEEAAKNNAAETELPPDASSQLSTLSSALPATSLRRKLAAFLALTKPRLSFLIVLTTTSAYGMYPISSLLTLDPSMTPLPTLSTSTLTFLYLTTGTFLSSCSANTLNMLLEPKYDALMSRTRNRPLVRGLLSRRAAVLFAIATAAAGLGLLYIGTNPTTTALSASNICLYAFVYTPLKRISVINTWVGAVVGGIPPLMGWTAAAGQTATTGHDSWRDMLFSKDSIGGWLLGGILFAWQFPHFNALSYMIREEYKAAGYRMLAWTNPAANARVALRYSLLMFPFSVGLWWVGVVGNGFLVGSTAANGWLVKEAYKFWRHQGANGSARRLFWASIWQLPILLVGGLVTKKGLWDGVWNNVFGQPVEDEDDYLWEDEDEVAEAERKMIPAKTSSS
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CSP_PLAKU
Sequence: MKNFILLAVSSILLVDLLPTHFEHNVDLSRAINVNGVSFNNVDTSSLGAAQVRQSASRGRGLGEKPKEGADKEKKKEKEKEKEEEPKKPNENKLKQPEQPAAGAGGEQPAAGAGGEQPAAGAGGEQPAAGARGEQPAAGAGGEQPAAGAGGEQPAAGAGGEQPAAGAGGEQPAAGAGGEQPAAGARGEQPAAGAGGEQPAAGAGGEQPAAGARGEQPAAGAGGEQPAPAPRREQPAPGAVAGDGARGGNAGAGKGQGQNNQGANVPNEKVVNDYLHKIRSSVTTEWTPCSVTCGNGVRIRRKGHAGNKKAEDLTMDDLEVEACVMDKCAGIFNVVSNSLGLVILLVLALFN
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: PYRH_METBU
Sequence: MLIVLSVGGSILAKNLDPKHFSAYASALKELARKHQIVVVTGGGVAARNYIDVARGVGANEVVCDFIGIDITRLNAQLLIAALGNTAHPEPPTTYKEAESALASGKIVVMGGVIPGQTTDAVAAILAEYLNADMMVIATSVDGVYSSDPREDPNAKKFDVMTAKELVGIVISTEMKAGSKSPVDPLASKIIERCNIDTIIMDGTDPQDVLEVVLQEAVKTDKVTGVRLGTRIIG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSD_STRCO
Sequence: MTQLPGLLDTEAIRKDFPILDRQVHDGHKLVYLDNAATSQKPRQVLDALSEYYERYNANVHRGVHVLAEEATALYEGARDKVAEFINAPSRDEVIFTKNASESLNLVANMLGWADDPYRVDHETEIVITEMEHHSNIVPWQLLAQRTGAKLRWFGLTDDGRLDLSNIDEVITEKTKVVSFVLVSNILGTQNPVEAIVRRAQEVGALVCIDASQAAPHMPLDVQALQADFVAFTGHKMCGPTGIGVLWGRQELLEDLPPFLGGGEMIETVSMHSSTYAPAPHKFEAGTPPVAQAVGLGAAIDYLNSIGMDKILAHEHALTEYAVKRLLEVPDLRIIGPTTAEERGAAISFTLGDIHPHDVGQVLDEQGIAVRVGHHCARPVCLRYGIPATTRASFYLYSTPAEIDALVDGLEHVRNFFG
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: YIF1A_DANRE
Sequence: MNFQQQGYRATKPRARASPPTGGPMLFDDTSSGPPPMNNQNYYSSGYNMAEMPAGGQEPGVGNIFADPMANAAMMYGSTLANQGKDIVNKEINRFMSVNKLKYFFAVDTKYVMKKLLLLMFPYTHQDWEVRYHRDTPLTPRHDVNAPDLYIPTMAFITYILLAGMALGIQKRFSPEVLGLCASTALVWMIIEVLVMLLSLYLLTVHTDLSTFDLVAYSGYKYVGMILTVFCGLLFGSDGYYVALAWSSCALMFFIVRSLKMKILSSISADSMGAGASAKPRFRLYITVASAAFQPFIIYWLTAHLVR
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Protein YIF1A, YIP1-interacting factor homolog A.
What is the protein family that this protein belongs to?
Belongs to the YIF1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the endoplasmic reticulum-Golgi intermediate compartment.
Protein: BXL4_ARATH
Sequence: MGSSSPLTRRNRAPPSSVSSVYLIFLCFFLYFLNFSNAQSSPVFACDVAANPSLAAYGFCNTVLKIEYRVADLVARLTLQEKIGFLVSKANGVTRLGIPTYEWWSEALHGVSYIGPGTHFSSQVPGATSFPQVILTAASFNVSLFQAIGKVVSTEARAMYNVGLAGLTYWSPNVNIFRDPRWGRGQETPGEDPLLASKYASGYVKGLQETDGGDSNRLKVAACCKHYTAYDVDNWKGVERYSFNAVVTQQDMDDTYQPPFKSCVVDGNVASVMCSYNQVNGKPTCADPDLLSGVIRGEWKLNGYIVSDCDSVDVLYKNQHYTKTPAEAAAISILAGLDLNCGSFLGQHTEEAVKSGLVNEAAIDKAISNNFLTLMRLGFFDGNPKNQIYGGLGPTDVCTSANQELAADAARQGIVLLKNTGCLPLSPKSIKTLAVIGPNANVTKTMIGNYEGTPCKYTTPLQGLAGTVSTTYLPGCSNVACAVADVAGATKLAATADVSVLVIGADQSIEAESRDRVDLHLPGQQQELVIQVAKAAKGPVLLVIMSGGGFDITFAKNDPKIAGILWVGYPGEAGGIAIADIIFGRYNPSGKLPMTWYPQSYVEKVPMTIMNMRPDKASGYPGRTYRFYTGETVYAFGDGLSYTKFSHTLVKAPSLVSLGLEENHVCRSSECQSLDAIGPHCENAVSGGGSAFEVHIKVRNGGDREGIHTVFLFTTPPAIHGSPRKHLVGFEKIRLGKREEAVVRFKVEICKDLSVVDEIGKRKIGLGKHLLHVGDLKHSLSIRI
What is the function of this protein?
Beta-D-xylosidase showing an optimal efficiency with the natural substrate xylobiose.
What are the official names of this protein?
Beta-D-xylosidase 4, AtBXL4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_FUSNN
Sequence: MNPVFLKIGPIELHYYGLMYAIAFFVGISLGKKIAKERNFDLDLVENYAFVAIISGLIGGRLYYILFNLPYYLQNPFEILAVWHGGMAIHGGILGGIAGTLIFAKIKKINPLILGDFAAGPFILGQAIGRIGNFMNGEVHGVPTFTPFSVIFNVKPKFYEWYTYYQSLSISDKANYPDLVPWGVVFPTSSPAGSEFPNLALHPAMLYELILNLIGFFIIWFILRKKENKASGYMWWWYIIIYSINRIIVSFFRVEDLMFFNFRAPHVISIILIAVSIFFLKKDNKKVF
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOA_PHAAN
Sequence: MVQEKLRFSTRTLQWKCVESRIESKRLYYGRFILSPLMKGQADTIGIAIRRILLGEIEGTCITRVKSEKIPHEYSTIIGIEESVHEIFMNLKEIVLKSNMYGTQDASISFKGPGYITAQDIILPPSVEIVDNRQHIANVTEPVNLCIELKIERNRGYRIKTLKNFQDGSYDIDARFMPVRNVNYSIHSYVNGNEKQEILFLEIWTNGSLTPKEALYEASQNLIDLFIPFLHAEEENFNLEKKKHKVTLPLFTFHDILVKDKLRKNKKEIALKSIFIDQLELPPRIYNCLKRSNIHTLLELLNNSQEXLLKIEHFRVEDGKSILDILKIQKYFT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DXS_HAEIG
Sequence: MTNNMNNYPLLSLINSPEDLRLLNKDQLPQLCQELRAYLLESVSQTSGHLASGLGTVELTVALHYVYKTPFDQLIWDVGHQAYPHKILTGRREQMSTIRQKGGIHPFPWREESEFDVLSVGHSSTSISAGLGIAVAAERENASRKTVCVIGDGSITAGMAFEALNHAGALHTDMLVILNDNEMSISENVGALNNHLARIFSGSLYSTLRDGSKKILDKVPPIKNFMKKTEEHMKGVMFSPESTLFEELGFNYIGPVDGHNIDELVATLTNMRNLKGPQFLHIKTKKGKGYAPAEKDPIGFHGVPKFDPISGELPKNNSKPTYSKIFGDWLCEMAEKDAKIIGITPAMREGSGMVEFSQRFPKQYFDVAIAEQHAVTFATGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRAGIVGADGATHQGAFDISFMRCIPNMIIMTPSDENECRQMLYTGYQCGKPAAVRYPRGNAVGVKLTPLEMLPIGKSRLIREGQKIAILNFGTLLPSALELSEKLNATVVDMRFVKPIDIEMINMLAQTHDYLVTLEENAIQGGAGSAVAEVLNSSGKSTALLQLGLPDYFIPQATQQEALADLGLDTKGIEEKILNFIAKQGNL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y792_STAEQ
Sequence: MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTITSGREEVENNLSQNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIEGEKEISVQQFAESFQAGVETAYKAVMKPVEGTILTVAKDAAKAAMDYVDQAEDCVDLMVHVIEAASESLDNTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKGLKGEKVEAQAPKLDTESFVNDDHDFHGVINTEDIVYGYCTEMMVRFGKNKKAFDEQEFRNDMSEFGDSLLVINDDEIVKVHVHTEHPGDVFNYGQKYGELIKLKVENMREQHREVIRKEQDGIQNKATNESKTVETAIVTISVGDGIAELFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNIMMASEQAASIVEAETVVIPTKSIPQGISALFQYDQESNLEDNKSHMNDALETVQSGSITFAVRDTKIDGIEIKKDEFMGLAEDKIVISDFNQFHAVKGLLSKLLNEDSEILTMISGEDADNSITNQIIDWIESEYPDVEVEQHEGGQPIYQYFFAVE
What are the official names of this protein?
Uncharacterized protein SERP0792.
Protein: YPE2_NPVLD
Sequence: MILQKYNSRIMTESALKADFTDYLLNVKAIVEFVKKYFKEDPTGEDYKRFTDSVLKLLGDLIDDYVDGKLFAADGEFLAD
What are the official names of this protein?
Uncharacterized 9.2 kDa protein in PE 5'region, ORF2.
Protein: DER_CHESB
Sequence: MPFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGLEEAAAPTLAGRMRAQTETAIDEADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANKTDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIAEFAGQAEEEERVTEEETVLIGEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVDWHWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQIADLIVREGRAPVIAFNKWDLIENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLDQLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSGRRLKVKYMTQVKTRPPGFVLSCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: HIS1_BACCZ
Sequence: MRNIQIALTKGRLEKHVIPLFEQIGIDCSELKNKGRKLVFQSKNTDISFILVKAVDVATYVEHGVADIGVVGKDILMENEKDIYEMLDLGVGVCKFCVASIPTYNPKSYRKKCIATKYPHITSNYFHNKGEDVEIIKIEGSVEIAPILGLADAIVDIVETGKTLQENGLIVFEEMYSISARMIVNKAALKTKKDEIFSIINMMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_KLEP3
Sequence: MNDVTEASLPKAIFLMGPTASGKTALAIALRKVLPVELISVDSALIYRGMDIGTAKPDAAELSAAPHRLLDILDPAEAYSAADFRRDALAAMADIVAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWNALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDMPSIRCVGYRQMWSYLNGEIPYDEMVYRGVCATRQLAKRQVTWLRGWEGVHWLDSEQPEQALNKVLQVVGASQN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: FMT_ROSCS
Sequence: MSLRIVFLGSPTFAVLPLERLVADSRYQVVGVVTQPDRPAGRGKMPVATPVKQAALRLGLPVLTPETLRDPAAVADLADLRPDVGVVAAYGEILRRDVLAIPPLGYVNIHPSLLPLYRGPSPVAGAILNGDAETGVTIMVIEAKMDAGPILAQRVVPLPPDARTGSLTRELFAIGADMLLETLDAYATGAITPHPQDHARATFTKLLSREDGIIDWSQPALRIERMTRAYDPWPGATTTWRGAPLKIIAARVRSDRHSDAPPGTLLDTAEGLAVATGDGLLVLETVQPAGKRPLPAADWRRGVRLTGGERLGG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LSPA_RHOPT
Sequence: MTPVRLGILTAVIALALDQATKLWLLYGFELARKGVVPVTSFFDLVLAWNTGISYGWFAGQGPTGQILMLAFKAVAIVALAIWMARSTTKLATIGLGLIIGGAIGNAIDRLAYGAVVDFALFHVEIAGKTYNWYVFNIADVAIVVGVVALLYDSLIGAPAVKAP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RYBP_MOUSE
Sequence: MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:22325148, PubMed:28596365).  Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females (PubMed:28596365).  May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites (PubMed:22325148, PubMed:28596365).  Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes (By similarity).  May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis (PubMed:17874297).  May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1 (By similarity).  May bind to DNA (PubMed:19170609).  May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3 (PubMed:27748911).
What are the official names of this protein?
RING1 and YY1-binding protein, Death effector domain-associated factor, DED-associated factor.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies.
Protein: YFHE_SCHPO
Sequence: MTHTPSFDLSDIKSTLSTNVLHADDAYALENDVAPPIHISTTYTYPGTPDTLQPFTKLAEEDFPYYARISGNNVDRAEASLSSVLGAPSVVYSSGLAAIYGLLSYLNPKHIAVHKPGFGGYSGTIQIIARINRLTGLETSFIDGKCDAIGEGDVIWLETPLNPLGIAFDIPFYKELAKKKGAILVVDSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRSKILDLKADRAYLGTILHPQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNKLATDEQFATSLGIDSSLILEVYHNSLQTKEFVAKNLTGGHASCFSVLLKSDTVAKHLCCELKYFHHATSLGSVESLIEWRRMTDSKIDPRLVRLSIGIEDAADLIADLNRVFASLS
What are the official names of this protein?
Uncharacterized trans-sulfuration enzyme C23A1.14c.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: NU205_HUMAN
Sequence: MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540).  May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC (PubMed:15229283).
What are the official names of this protein?
Nuclear pore complex protein Nup205, 205 kDa nucleoporin, Nucleoporin Nup205.
What is the protein family that this protein belongs to?
Belongs to the NUP186/NUP192/NUP205 family.
Protein: RL3_ECOSM
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TMM65_DANRE
Sequence: MIRSVLLRALAARPPSAPVPGHLHRCLLGTHRRKIKPEQLELPNQTREFVYSLSPETRSRLLKELQTFESKTEDSGEASRLTAAQLRYILLHNAIPFIGFGFLDNAIMIAAGTQIELSIGLTLGISTMAAAALGNLVSDLAGLGLAGYVEALAVRLGMQIPDLSPRQVDMWQTRVSSHMGKAIGVAIGCILGMFPLLFLSDEEDKKPKKDSN
What is the function of this protein?
May play an important role in cardiac development and function.  May regulate cardiac conduction and the function of the gap junction protein GJA1.  May contribute to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (PubMed:26403541).  Regulates mitochondrial respiration and mitochondrial DNA copy number maintenance (By similarity).
What are the official names of this protein?
Transmembrane protein 65.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein. Note=Localizes at the intercalated disk in ventricular tissue and cardiomyocytes.
Protein: PTHR_HORSE
Sequence: HQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPAPNTKNHPVRFGSDDEGRYLTQETNKLEPYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLNSEVAESGLDGDHLSDFSTTSPELYLRRH
What is the function of this protein?
Osteostatin is a potent inhibitor of osteoclastic bone resorption.
What are the official names of this protein?
Parathyroid hormone-related protein, PTH-rP, PTHrP.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted.
Protein: ENVE_SALTY
Sequence: MTLLSGKTTLVLCLSSILCGCTTNGLPTPYSINLSFPVITQNQINSGGYYINDAEQIRTTDGLCLDAGPDQQNRLTLRECKHVQSQLFSFHRDRITQGEKCLDAAGQGTKEGTPIILYSCTGNDNQRWLTDDNKIKGKQSRKCLGTNSIIVRKGDPVVLADCDFSRALEFTIR
What are the official names of this protein?
Probable lipoprotein EnvE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: FOLD1_RHIEC
Sequence: MATVIDGKNVAASVIQTVKSATAALEKASGVTTGLAVIIVGDDPASHAYVGSKSRMAKECGFKSVQHTLPAETTQEELAGLVATLNADPSIHGILVQLPLPKPLDSEPIIQSILPEKDVDGLSVVNAGKLATGDLKTGLVSCTPAGAMVFVRRTHGEDLSGLNAVVIGRSNLFGKPMAQLLLNANATVTIAHSRTKNLAEVCRNADILVAAVGRPEMVKADWVKPGATVIDVGINRVPAPEKGEGKTRLVGDVAFREVSEIASTITPVPGGVGPMTIAMLMANTVIAAHRAAGQTPPQF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DIM1_CANGA
Sequence: MAKADKKKYSGATTNKQVAAEKHLTSVFKFNTDLGQHILKNPLVAQGIVDKAQIKPSDIVLEVGPGTGNLTVRILEQARKVVAVEMDPRMAAELTKRVHGTPAEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHIMKVGRNNFRPPPQVESSVVRIEIKNPRPQIDFNEWDGLLRIVFVRKNRTISAGFKSTTVLEILEKNYKTFLAINNQSIDETENLQSLIKQKIETVLKETGLAEKRAGKCDQTDFLKLLYAFHQVGIHFS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
What are the official names of this protein?
Dimethyladenosine transferase, 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, 18S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: SYE_MICAN
Sequence: MTVRVRIAPSPTGNLHIGTARTAVFNWLFARHHRGKFILRVEDTDLERSRPEYTENIQAGLQWLGLNWDEGPFFQTQRLNYYRQAIQTLLDRGLAYRCYCTPEELEKMREEQKARNLAPRYDNRHRYLTPEQQAQFEQAGRKAVIRFIIDDDQEIIWQDLIREKVIWKGSDLGGDMVIARTSENGEENFGQPLYNLAVVVDDIDMEITHVIRGEDHIANTAKQILLYEALGAKVPEFAHSPLILNQEGRKLSKRDGVTSIDDFRKLGFLPQALVNYMTLLGWTPPDSTEEIFTLEAAAEVFSLERVNKAGAKFDWTKLDWINSQYLHRLTGEELVPLLLPYWQEAGYNFAAETDRAWLIGLATLIGPSLTRLSDAVAESRLLLTPLANYNQEALSQLQLEGVKDIIKDILAAITPDLTGEVAKGIVETTTKAHRVKKGLVMKSLRAALMGELHGPDLMQSWLLLNQKGWDISRLQQAVNS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.