PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_CAMJD
Sequence: MQKYLEKANVLIEALPYIRKFNSKIILIKYGGSAMENEELKHCVMQDIALLKLVGLKPIIVHGGGKDISAMCEKLGVKSEFKNGLRVSDKATTEVASMVLNHINKNLVHSLQNLGVKAIGLCGKDGALLECVKKDENLAFVGTIQKVNSKILEELLEKDFLPIIAPIGMDEDFNTYNINADDAACAIAKALRAEKLAFLTDTAGLYEDFNDKNSLISKISLEQAKILAPKIEGGMHVKLKSCIDACENGVKKVHILDGRVKHSLLLEFFTDEGIGTLVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2218_IDILO
Sequence: MNSLQNHLLIATPMLNDPMFKRTVTYICEHNEEGAMGLVINQPADLSVTSLLDKLEIVYPENNQHLQGSVYQGGPVGRERGFVIHPPQDNWRASQKMSDDIMVTTSRDILEALGSSAAPPQFLLTLGYAGWEAGQLEEELGENSWLAIPADPELLFNTPPSERWQKATEQLGFDVWQLGPDVGHA
What are the official names of this protein?
UPF0301 protein IL2218.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RPOZ_LARHH
Sequence: MARITVDDCLKRIPNRFDLTLAAAYRARQIANGAQLLIDSNAGSKDKPTVVALREIAAGQIGREVLERAIRS
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: GATC_PAEAT
Sequence: MAAINRDDVAHLARLAHIEMSAEELDRMAVELAVIVDSVKSVSEAAGEDVPATSHPIPLTNVFREDVVGHTFTAEQALSGAPDSYENRFKVPAILDED
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: GLYA1_CUPPJ
Sequence: MFERSRYTIDQIDPEVFAAIQKENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVYFAVLKPGDTIMGMSLAEGGHLTHGMALNMSGKWFNVVSYGLNAQEDIDYDALEKLAQEKKPKLIIAGASAFALRIDFERIGKVAKSIGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEHEKAINSSIFPGIQGGPLMHVIAGKAVAFKEALTPEFKAYQEQVVKNAAVLAETLIARGLRIVSGRTESHVMLVDLRAKNITGKEAERILGEAHLTVNKNAIPNDPEKPFVTSGIRVGSPAMTTRGFKEEEARIVGNLIADVLDNPHDAGNIASVREQVSALTKRFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_METM6
Sequence: MLMFQKPKGTRDFLPEEMKKRKNIEKKLRKVFDSYNFSEINTPTFESFELLSKKTGEEIRKQLFVFKDHGDREMGLRPELTSSVARFYINEFKNTPKPVKLYYFTNCFRYENPQAGRYREFWQMGSELIGSKKPIADAEVINLAIEGLKEINMDFEINIGHLGVLKGVFEKYDLSDDEGNEIRRLIDKEDMDGLKTALSRIESEKNIEISEKVFEVLELKGGREVISKLKEKLSEFESSVTALENLDSILEFVPHEYIINFGIARGLDYYTGMVFEIYGKREGARQVCGGGRYDNLIELFEGEPSPAVGFAYGFDRIMLNIDDFEVEEESIFVVPVKSSDMLLNECLKIAKTLRDAGKAVELDLMGRKLNKALNYANTKGIKKVLIVGENDILEGKVALKNMETGEQSLIELKDILTI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_FRATH
Sequence: MYISNLRLQNFRNIPAKSFDFKNSINFIVGKNGSGKTSILESIYFLSHSRSFRSSQLNRIINHNADEFIIYTKAYNPDEITISLSRKKNSNNISKLNLEIQKNHTEITRNLPIQLINPESFNIINSGAQQRCKVIDWGAFYLDKTFLKIWQQTKFLVKQRNSALKQNYPYSYILSIDKKLCEFAEILDYKRQAYFTKLKPKIYEILSHFNPNLQLDIDYFRGWNLHKSLAQVLEESFNYDNKYKVTNHGPHKADIVLSVSHKPIQDIFSRGQQKLLICALKLAQGEIHNSENDNKCIYLIDDITSELDSIHTLTLFNYLKQLKSQVFITTTEKNKINEFIDTNSYILEI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG056_CAMPM
Sequence: MLNRVQILMKTANNYETIEILRNYLRLYIILARNEEGHGILIYDDNIDSIMSMMNITRLEVIGLTTHCTKLRSSPPIPMSRLFMDEIDHESYYSPKTSDYPLIDIIRNRSHEQGDIALALERYGIDNTDSISEINEWLSSKGLACYRFVKFNDYRKQMYRKFSKCTIVDSMIIGHIGHHYIWIKNLETYTRPEIDVLPFDIKYISRDELWVRISSSLDQTHIKTIAVSVYGAITDNGPMPYMISTYPGNTFVNFNSVKDLILNFLDWIKDIMTSTRTIILVGYMSNLFDIPLLTVYWPNNCGWKIYNNILISSDGARVIWMDAYKFSCGLSLQDYCYHWGSKPESRPFDLIKKSDAKRNIKSWVKESMTSLKSLYEAFETQSGALEVLMSPCRMFSFSRIEDMFLTSVINRVSENTGMGMYYPTNDISSLFIESSICLDYIIVNNQESNKYRIKSVLDIISSKQYPAGRPNYVKNGTKGKLYIALCKVTVPTNDHIPVVYHDDDNTTTFITVLTSVDIETATRAGYSIVELGALQWDDNIPELKDCLLDSIKMIYDLNAATTNNLLEQLIENINFNNSSIILLFYTFAISYCRAFIYSIIETIDPVYISQFSYKELYISSSYKDINEVMSQMVKL
What is the function of this protein?
Plays a role in intracellular enveloped virus (IEV) transport to the cell surface through microtubule transport.  Together with protein OPG064, forms a complex that interacts with host KLC2 (kinesin light chain isoform 2) to engage the kinesin-1 complex and thereby promote IEV trafficking.
What are the official names of this protein?
Protein OPG056, Protein F12 homolog.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG056 family.
Protein: ALLTR_PENRU
Sequence: GFKNVALSTARGF
What are the official names of this protein?
Allatotropin-related peptide, ATRP.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMD_SHEWM
Sequence: MAQFFKAKPNSSKQLSAKVSLQVTRLDHLGAGIAQHNGKVVFIPGVLPGEKAMVQLTEQKKRYSRAKLLNLETHSIDRVEPKCAHYHQCGGCDLQHLSLEKQRLHKESALVSLMAKLSHTEAEALVPAIIGEQWHYRRRARLATFYHQETKRTTLGFRAQSSKEVIDISSCPVLAKSLSELISPLSKLLNQLASRRALGHVELIDVDNGQFVVVRATKELSDKDKEKLLSFAQEHKVNLIVQGNEGELLVIKGPKELPFYTLNSDIKLSFTPGNFVQVNGEINRAMVDQAVQWLDVKADERVLDLFCGVGNFSLPLAKSGAEVIGVEGVPEMVAQARINAKQSDLSDVTFFHTDLSADLSKEPWLGKVDKLLLDPARAGAFESLQWLKKMKPKSIVYVSCDPSSLARDSEPLLKHGYKLKKLGLVDMFPQTHHIEAMALFELS
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: RS4_CARGR
Sequence: MARGPKKHLKRLNAPKAWMLDKLGGVYAPRPSTGPHKLRESLPLVIFLRNRLKYALTNSEVTKIVMQRLIKVDGKVRTDPNYPSGFMDVITIEKTGEFFRLIYDVKGRFTIHRITAEEAKYKLCKVKRVQTGPKGIPFLVTHDGRTIRYPDPIIKVNDTIQLEIANSKIMDSIKFDSGNLCMITGGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHTFANRLNNVFIIGKGSKAYVSLPRGKGVKLSIAEERDKRLAAKTH
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: SYM_XYLFM
Sequence: MRYSHPLVPLSFMTTALVTTALPYANGPLHLGHLVGYIQADIWVRARRLGGHNTWFVCADDTHGTPIMLAAEKAGMPPEAFIATTQASHERDFAAFNVAFDHYDSTHSPVNRHLTEQSYLTLKQAGHITCRSVAQFYDPAKGMFLPDRYVKGTCPNCGATDQYGDNCEACGATYDPTELKNPYSVISGATPELRDSEHFFFEVAHFDTFLRHWLSGDVALPSVKNKLKEWLDAKGGLRPWDISRDAPYFGFEIPDQPGKYFYVWLDAPIGYLCSFKTLCTRIGEDFDTHLRSGTTTELHHFIGKDIVNFHALFWPAVLHGTGRCAPTRLHVNGYLTVDGAKMSKSRGTFIMARTYLDAGLEPDALRYYFAAKSSGDVDDLDLNLSDFVARVNADLVGKLVNLASRCASFIGTRFNGQLADILPDRIQYDQFVAALTPIRDAYERNDTASAIRQTMQLADEANKYIDETKPWIIAKQHHADAQLHAVCTQGLNLFRVLITALKPILPHTSIQAETFLAAPVTTWQDVNQPLTGGHTIQPYSPLFTRIDKKIIEVMINASKDTLAPPPASAKQQNASMSNTAPPPTAEEPETTAPTIGIDDFAKLDLRIGKVLVCEYVEGSDKLLRFELDAGPLGKRQIFSGIRASYSNPETLIGRNVVFIANLAPRKMRFGISQGMILSAGFDSGTLALLDADSSAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_EPIVI
Sequence: MYKQNLFIISSNDSKYNFLLRNKKLYYEIILEGLTFILEFFFFIRLISYLEGKKNKIEKLNNLRSILSIFPFLEDNFSNLKFILDILIPRKVHAEILVQTLRYWIKDATYLHLLRFWLNNNWNSIINQNKDGYFYPQKNKILLLLYNSYVCKYESIFVFLRNQSYHFRSTPFIMLLERIYFYFKIERLVNPFLKVKDFKANLWLIKEPCLHYFRYRRQYILASKGTSLFLNKWKCYVITFWQWYFSLWFFSRSIYIKKLLNNSFEILTYHSSLNINPSFVLSQILETPFISNNTIKKVNILVPIILSISDKEKFFNVLGHPTSNLFRVDLSDYNIIGRLECIYRNLYHYLSGSSKKNSLYLIKYILLLSCVRTLARKHKSTVRTFAFQKKRLCLELLEGFFISEEDILFLKFQKVYSSLGGVYISQFWYLNIYSINYLA
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Its retention as a freestanding gene in this organism suggests it acts in trans to assist in splicing chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: PPR40_ARATH
Sequence: MHQTLGAVRLAYRSRIANLVKSGMIDNAVQVFDEMRHSSYRVFSFDYNRFIGVLVRESRFELAEAIYWDMKPMGFSLIPFTYSRFISGLCKVKKFDLIDALLSDMETLGFIPDIWAFNVYLDLLCRENKVGFAVQTFFCMVQRGREPDVVSYTILINGLFRAGKVTDAVEIWNAMIRSGVSPDNKACAALVVGLCHARKVDLAYEMVAEEIKSARVKLSTVVYNALISGFCKAGRIEKAEALKSYMSKIGCEPDLVTYNVLLNYYYDNNMLKRAEGVMAEMVRSGIQLDAYSYNQLLKRHCRVSHPDKCYNFMVKEMEPRGFCDVVSYSTLIETFCRASNTRKAYRLFEEMRQKGMVMNVVTYTSLIKAFLREGNSSVAKKLLDQMTELGLSPDRIFYTTILDHLCKSGNVDKAYGVFNDMIEHEITPDAISYNSLISGLCRSGRVTEAIKLFEDMKGKECCPDELTFKFIIGGLIRGKKLSAAYKVWDQMMDKGFTLDRDVSDTLIKASCSMSADA
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g13040, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GATA_CLOBH
Sequence: MDLTKLTAHELKDMLSNKEVKAEEITKAFLDRINLVDNKLGAYLYVSEEEAIKKAKEIDGKIEKNEELKALSGIPVGIKDNINVKGMQNTCASKILEGYTSPYDAHVTEKIKQEEGIILGKLNMDEFAMGSSTENSAFKLAKNPWDLERVPGGSSGGSAVAVAGSEATLSLGTDTGGSVRQPASFCGVVGLKPTYGRISRSGVVAFGSTLDQVGPMGKDVEDCALLTSVIAGLDKKDFTTVDKEVPDYKKSLTKDIKGKRIGIPKEFFGDGLDKNVRKSVEEAIKVLEANGAEVKPCSLPLMDYALSAYYIISSAEASSNLARFDGIRYGYRSKNFKDAKDIYLKSRSEGFGDEVKRRIMLGTYVLSAGYYDAYYKKALKVRKLIKDDFQRVFKEFDAIVSPTSPTTAFKVGEKKDDVMSMYLSDIYTVPISVAGVPAISLPCGMIDGLPVGLQIISDYFKEDVLFNLAYNYEQSVDFHKMRADF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: COAX_HELPH
Sequence: MPARQSFTDLKNLVLCDIGNTHIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKALLNCYPNAKNIAGFFHLETDYIGLGIDRQMACLAVNNGVVVDAGSAITIDLVKEGKHLGGCILPGLAQYIHAYKKSAKILEQPFKTLDSLEILPKNTRDAVNYGMILSVISCIQHLAKNQKIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGILECK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PROMM
Sequence: MSISNPSAASEHLVSVSAPAKINLHLEVLGLRSDGFHELAMVMQSIELADQLHFRNTADGSISLRCDDSSLSTAGDNLIVRAAHLLRERSGFSDLGAAIELQKRIPIGAGLAGGSSDGAATLVGLNGLWNLNFSQGQLEGFAAELGSDMPFCLAGGSQLCFGRGERLESLQAMKASMAVVLVKDPSVSVSTPWAYGRCKELFSSRYLSKESDFEQRRQQLRESSWLNPLRADDPPPLRNDLQEVVAPEVSAVQTTLKLLTDLPGSLAVSMSGSGPSCFALFADVASAQAALQLQQPAFAAAGLSSWCCAFRCEGIKLEA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: THRB_SALSA
Sequence: SFGSGELVXGEXPXFEKIIVKGIDAEVASAPMQVML
What is the function of this protein?
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.  Functions in blood homeostasis, inflammation and wound healing (By similarity).
What are the official names of this protein?
Thrombin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCF3_MESVI
Sequence: MPRSQKNDNFIDKTFTVVADIILKVLPTTVREKAAFSYYRDGMSAQAEGEYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHGKALEYYYQAIERNPSLPQALNNIAVIYHYRGEQAIEEGNIATSEILFNQAASYWKQAIRLAPNSYIEAQNWLKITGRIEDNINL
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GRC3_ASPOR
Sequence: MKRKAEKQQAAAPAPMSAVAARKARQQQMQAAIAVVKPSQAESVQEPPSKKARRSPEQAAPTPPASGEPQGRTTRSSKRKAESLKVDKLIEKKEKTLSAEYTEQLPVRSSPQEQEDQSSSDEESEEQNPIVGENDAGIAPLRGDVDGYESPADTSGPIQEFPLSKTRLNKSNIIYSDEHTLCVRIKEKMSLVLLGHYDLWVKRGVVSVMGAKLHPSPRLYRVYAPSTHSLPVIKCVSGVDGAAEIEVKSCHSGIYRLRDLSPLYRRIWNGKNTSADKLTLRTSPSSAKRTFSVLYTSADDSFKRHLRPLHLEKQWSSAIKSLSQRGGRLKALICGPKASGKSTFSRYLLNHLLSPAPQTETNYCNTDGVAFLDLDPGQPEFSPMGQVYLAHLRSPVFGPPFSHPSLDSSQEGTIIRAHHIGATSPKEDPDHYVLAAMDLMDRYRALLASYPQCPLIINYPGWIFGLGLEVATWLVRSLGLSDVVYMSEKGPTEVVMPLGQAAQEAMAPLTILPSQPTDFVSRSSAQLRSMQMQSYFHMTRPTEISNPLWLEKPISRTRPFHVHYAGPKQGIKGVMVMGSQIDPDLLQEVLDGSIVAVVAVESPQAILGQNDGPGLTINHPAQPIDADVTMDDSTDTPMEGVPLQDPINPFIDANIVRTPTENLPYLFVGSGSSNPLDPKASRCLGLALVRSIDVSSQRLELVTPIAGSAIRDALEQSHGIVLVRGQLDNPNWAISEDYYAARAEERRYRESLEKLKKNEATTDKEDSIIEPEQQARVSAILRDRIRRASNVPWMTVIEDNSGHQREAAQREKSLWKLRKKAYPGSDSEGDW
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase grc3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DRD2_MOUSE
Sequence: MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity).  Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (PubMed:30936473).
What are the official names of this protein?
D(2) dopamine receptor, Dopamine D2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CEP43_BOVIN
Sequence: MAATAAAVVAEEDTELRYLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTFQGLEGRENLARDLGIIEAEGTVGGPLLLEVIRRCQQKEKALTSGEGALDLSDVHSPPKSPEGKTGAHTPPSKIPRYKGQGNKKTSGQQPGAKKASNDASHSDTSISSSEPKSRSGLHLLAHETKIGSLLSNNSLDVNAKAGPGPEEDDLEGDSFFDDPIPKPEAAYGWRSEPSKQAGSLASLSDAPPLKSGLSSLAGAPSLKESESKRGNTVLKDLKLVNDKIGSLGLGTGEEDDYVDDFNSTSHRSEKSELSIGEEIEEDLSVEMDDVNTSDKLDDLTQDLTVSQLSDVADYLEDVA
What is the function of this protein?
Required for anchoring microtubules to the centrosomes.  Required for ciliation.
What are the official names of this protein?
Centrosomal protein 43, FGFR1 oncogene partner.
What is the protein family that this protein belongs to?
Belongs to the CEP43 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associated with gamma- tubulin. Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole. Localizes to the distal end of the centriole partly to the subdistal appendage region.
Protein: T4S5_HUMAN
Sequence: MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH
What is the function of this protein?
Acts as a lysosomal membrane arginine sensor (PubMed:30956113).  Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (PubMed:30956113).  Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (PubMed:20399237).  CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (PubMed:20399237).
What are the official names of this protein?
Transmembrane 4 L6 family member 5, Tetraspan transmembrane protein L6H.
What is the protein family that this protein belongs to?
Belongs to the L6 tetraspanin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Localization to cell membrane increases during conditions of arginine depletion and translocation to lysosome membrane seen upon arginine repletion.
Protein: TPIS_PSEP1
Sequence: MRRPMVAGNWKMHGTRASVAELTKGLSNLALPSGVEVAVFPPALFINQVIDGLAGKEITVGAQNSAVQPEQGALTGEVAPEQLVEAGCKLVLIGHSERRQIIGETDEVLNRKFAAAQAKGLKPVLCIGETLEEREAGKTLEVVGRQLSSIIEAFGVKAFADAVIAYEPVWAIGTGLTATPQQAQDVHAAIRGQLAAEDAEVAAKVQLLYGGSVKAANAAELFGMPDIDGGLIGGASLNADEFGAICRAAGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_PSEPW
Sequence: MQIYKVGGAVRDRLLGRPVSDIDWLVVGASVEEMHAKGFRPVGADFPVFLHPKTGEEYALARTERKSGRGYGGFTFHASPEVTLEEDLIRRDLTINAMAEDDQGNVLDPFHGRADLEQRLLRHVSPAFAEDPLRVLRVARFAARYAPLGFRVADETLELMKQIAASGELQALTAERSWKEIERALMEDEPQVFINVLSDCAALKQLMPELEGDAAALAALTQAAEHHQPLHIRWACLLHNLKPASIKALNQRFKAPRECQELAMLVGECASNGHRALQLEPEDMLALLQKFDVYRRPQRFEDFISVCQMVARGSGQAYPQADYLRAAAAAARAVEAKPLVEAGLTGQALGEALRHQRLEALKAYKANAEN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: DHN2_PEA
Sequence: MSQYQNQYGAQTRKTDEYGNPMNQVDQYGNPISGGGGLTGEAGRQHYGTTGGATDHGHGQQHRGVDQTTGYGTHTGGVGGYGTKPEYGSTNTGSGYGTGTGYGGSGTTEYVREEHHGDKKGVMDKIKEKIPGTEQSRTHTDGTGYGSTGYGASGGGIGNTGQEYVREELTVHPGDKKHGSAGQEYVKEERRGIGNTGQEYVREEHRVDHGEKKGIMDKIKEKLPGTGGCTGH
What are the official names of this protein?
Dehydrin DHN2.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: RS13_POLSJ
Sequence: MARIAGINIPPQQHAEIGLTAIFGIGRTRARKICEACDIAYSKKIKDLTDGDLEKIRDQIALFTIEGDLRRETTMNIKRLMDIGCYRGFRHRRGLPMRGQRTRTNARTRKGPRKAAAALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYC_CHLCH
Sequence: MALAIYNSLSRTKEIFEPLHSGVVSIYVCGPTVYGHAHLGHAKSYISFDVVVRWFRQSGYKVKYIQNITDVGHLTDDADEGEDKIMKQARLEKTDPMEIAQFYTRSFYEDMDRLGVERPNIAPTATAHIPEQIALVETLLRKGYAYEVNGNVYFSVNSFAGYGKLSGRTDQEALQSGSRVGIRSEKRDASDFALWKKAEEGHIMKWQSPWSVGYPGWHLECSAMAMKYLGETIDIHGGGMENKFPHHECEIAQSEAATGKPYVRYWMHNNMVTVNGTKMGKSLKNFVNLKELLQTRNPLALRFFILQSHYRSPLDYSEAALDAAAQGLEKLHETLRRFRHQAAGSGSLDVTPYAERFSEAMNDDFNTPIAIAVLFDLSKAINSALDSKGIVEADRAAIEAFLTIAATNTLGIASNNLADEQSNGNSMQRLDKVMQIMLELRHNARKQKDFATSDKIRDMLLAAGIEIKDTKEGAVWSVKG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BARHE
Sequence: MATFSQKPTEVVKKWVIIDAENLVLGRLAAFVANRLRGKHKATFTPHVDDGDNVIVINADKISLTGKKYTDKKYYWHTGYIGGIKKRTARQILEGRFPERVVEKAVERMIPRGPLGRRQLKNLRVYAGSQHPHAAQQPEALDVGALNRKNKRIA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL19_BURTA
Sequence: MNLIAKLEQEEIERALAGKTIPEFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAKRNRGLNSSFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRAAAAQQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.