PharMolix/UniProtQA huggingface dataset:
Protein: KI15B_XENLA
Sequence: MPPGTKGDPSNVTQPLPCLPSAEEDAIKVFVRIRPPVEGTLTGVDGEQGSCLTALSSTTIRLHSKPEPKMFTFDHVANVDTTQESVFSSVAKNIVESCMNGYNGTIFAYGQTGSGKTFTMLGPSESDNFTHNLRGVIPRSFEYLFFLINREKEKAGDGKSFLCKCSFIEIYNEQIFDLLDSASAGLFLREHIKKGVFVVGAVEQVVTSAAEAYQVLSMGWRNRRVASTSMNRESSRSHAVFTVTIESMEKTNDIVNIRSSQLNLVDLAGSERQKDTQTEGVRLKEAGSINRSLSCLGQVITALVDVANGRQRHICYRDSKLTFLLRDSLGGNAKTFIIANVHPGSKCFGETLSTLQFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKKLKEQLSQLLSGQMPGDISVARAPSVGDNMDYMNTFIEAMMLLERSDSEKKALLQKVIQLEDLCNKKEKFIQSNKMIVKFREDHIVRLEKAHREGQISLSNNEQDNFIAELKEEIRTLKEQVEHHPRVAKYALENHSLREENKRIGSLQSVKRAQEVSAQMMAELEKAFLEASVSEKDRQVAPMHSTPIQLDNSSLMSAARMRERMLQLESELATSKQEYEEFKELTKKKQVEQESELQSLMKSNQHLENILDAIKENKRHEVSQLNRMHAETIKNMTTPTKAYNLRSRLVPRLSLDGISNGLTDTPKSGDVMDDIINEPIPPEMSEQAYEAIAEELRIVQEQVTALQVKLDEEESKNIKLEQQVNKLELCSTQIQELFNSERSNWNKEQQAFIAQIKSLEKQQQDNKNQEDVLKSEVHDLRVVLQSADRELSAVKGEYSLFREKQEKELSQLSARHMAVQLQLDNFRLEHETLLEEKRSLQDAFDNLEEVMKFETDQLKQELSDSKHENETLRAELSNLLELLETEKERRQKLTSQLEEDKESKTKELLQVVDENMHLRKQCSELVTKCEHQVTELQRLEHSLTSSKEMIADLEKKNTADKEVVVDLMNQIQVHRTTIIHKTESIDLLTRELEDINSKYSIVLLAKEECKTVNEEQEKQIEELRESLERKQSADNIEKELLCDDLAHATEELGKLTEAFNKQETMLHACEKELVEKEQLISELTNKVKLMTDLEITKTEQEKIKPSHSNSNSPVVLAQTPRTPVGNPYESEFANLQNRNTNLAVLISELNEERTLKNEEIIKLKMQLCETENMHLEIQNLQGICKELKSQLENCKKGMKDGNEQKPSDMQDLKREIEKEVSERMEKGKATEHILKLQAELEETRNLLCAKDHSLNELNNEMERTRSLEAKAFTEKEQIRSVLEAKYEETEKLSQELDMLRKQVSFLAEENGKILGHQNPNQKIQYLVKLKKENDKLLEEAEKLRIENLFLKETKKCEHCD
What is the function of this protein?
Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.  Required for centrosome separation and maintenance of spindle bipolarity during mitosis (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF15-B, Kinesin-like protein 2-B, Xklp2-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KLP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes during metaphase on spindle microtubules, with a strong enrichment at spindle poles. Localizes to the minus ends of spindle pole and aster microtubules in a dynein- and dynactin-dependent manner. Detected diffusively in the cytoplasm. Localized at the centrosome during the interphase and throughout mitosis (By similarity).
Protein: LIN7A_RAT
Sequence: MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQPQQNHMS
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
What are the official names of this protein?
Protein lin-7 homolog A, Lin-7A, Mammalian lin-seven protein 1, MALS-1, Vertebrate lin-7 homolog 1, Veli-1.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: FLIA_PSEAE
Sequence: MTAASGVRMYSKAQAQNSQEQLIQRYAPLVKRIAYHLLGRLPASVQVEDLMQAGMIGLLEAAKKYDAGKGASFETYAGIRIRGAMLDEVRKGDWAPRSVHRNTRMVTDAIRAIEARTGRDAKDHEVAAELQLSLEDYYGILSDTQGSRLYSFDDLLQDGEHGLPEDTSLSHNEPIHGLLDERFQAALADAIAKLPERERLVLALYYDEELNLKEIGEVLGVSESRVSQLHSQCAARLRARLADWRSA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor controls the expression of flagella-related genes (By similarity).  Required for the flagellin gene (fliC) expression.
What are the official names of this protein?
RNA polymerase sigma factor FliA, RNA polymerase sigma factor for flagellar operon, Sigma F, Sigma-28.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. FliA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_CERDE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFILPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWKEEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDSITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLVAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PRTY1_CLUHA
Sequence: ARRRRSSSRPIRRRRPRRRTTRRRRAGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-YI, Clupeine-YI.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y319_MYCGE
Sequence: MRLFRFLFKLCFLLLVLVGFAYLFLAIFYFGSLNPFELAQPMDVFNRFFSKEALDNISSNNGATATAQTSSLLQLLEGSSNGLDNRFPTEKSAFYAIPGYVDFLKNAKLPGFVEQFTPYLTKYVIPLGMAFVSGLIGTLIVNFFLNKITRSIKRRKRNMKKQEQEEYYDDSRSRRKRN
What are the official names of this protein?
Uncharacterized protein MG319.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUT_BRUMB
Sequence: MTAASSSAPTLGIIRLEHAKGLDLPAYETAGSAGMDLRAAVAEDRQIVLLPGRRTLVPTGLILEIPQGYEVQIRPRSGLAFKNGITCLNTPGTIDSDYRGEVKVLLINLGDDDFRIERGMRIAQAVFAPVIQPKIEERAKISETARGAGGFGSTGTA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PB1F2_I68A4
Sequence: MEQEQDTPWTQSTEHINIQKRGNGQRTQRLEHPNSIRLMDHYLRIMSRVGMHKQIVYWKQWLSLKNPTQGSLKTRVLKRWKLFSKQEWIS
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: WEE2_CHICK
Sequence: MDDWENNDFIQRLDFSSCGEEGEDRSINEEDTLSSSPIKHCDFQKWNSPLPATPHRKLSEIFLSRTKSWVSPTLKSSPGVSRTHGNAETPLHITWKKLQLCDTPHTPKSLLSKTAFPSPGAKVPPKGFRHLRFTPGADLDDSTQASLVNINPFTPESYRQMLFLPNGKRKAREIKLVHLAQSFCEKAEVQRKDSAVRPADRCPLKDSNMVSRYQKEFLELERIGVGEFGSVYKCIKRLDGCVYAIKRSKRPLAGSSDEQLALREVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEHCNGGSLQDVLLENAKRGQYFPEAKLKEILLQVSMGLKYIHNSGLVHLDIKPSNIFICHKLVVEGQAGQEESDSDDEFSSGVMYKIGDLGHVTSIANPQVEEGDRRFLANEILQEQYFHLPKADIFALALTIALAAGAGPLPHNGAMWHHIRKGNIPSIPQKLPNGFIELLKLMIHPDPMERPSATALTKHPILRPSLGKAVQLQKQLNVEKCKTAMLERELKAARLAQTLMKDQPLGNANLQESETSPKKNNKRLVGGKNCRSFSFTVG
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis.  Required to maintain meiotic arrest in oocytes by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry (By similarity).
What are the official names of this protein?
Wee1-like protein kinase 2, Wee1-like protein kinase 1B, Wee1B kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_CYAPA
Sequence: MNLINSTKIFSSLMIASVENNTAIFSLNTDILETNLINLLVIFFLLIYQGRPFFTALLEERRKTVLDKIKKSENSYNEALEKLKEAKSKLAQAELAAKQIYEEAEAVAESIKKTGLAQLEKDIKRIEETTQASINTQQLSVITYLRQQVALLALRRVVSQLKNYLKPELHSQFIDRKILQLRKQK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, cyanelle, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: ATPF2_BOVIN
Sequence: MWRRCLRLRDVGRRLLNLPRSGLTASEGLGPKLPTPIRAYVPPAERKRFYQNVSISQGEGGFEINLDHRKLRTPQGKLFTVPSEALAIAVATEWDSQQDTIKMYTMHLTTLCNTSLDNPTQRDKDQLIRAAVKFLDTDTVCYRVEEPETLVELQRNEWDPVISWAEKRYGVEIGSSTSITGPSIPARTREVLVSHLASYNMWALQGIEFVVTQLKSLVLTLGLTDLRLTVEQAVLLSRLEEEYQIQKWGNIEWAHDYELQELRARTAAGTLFVHLCSESTAVKHKLLQG
What is the function of this protein?
May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).
What are the official names of this protein?
ATP synthase mitochondrial F1 complex assembly factor 2.
What is the protein family that this protein belongs to?
Belongs to the ATP12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TEX10_PONAB
Sequence: MTKKRKRQDDFQKVKLKVGKKKPKLQNATPTNFKTKTIHLPEQLKEDGTLPTNNRKLNIEDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDKDANVRLAAVQLLQFLAPKIRAEQMSPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEQYPALITGRSSILLKNFVELISHQQLSKGLINRDRSQSWILSVNPNRRLTSQQWRLKVLVRLSKFLQALADGSSRLRESEGLQEQKENPHATSNSIFINWKEHANDQQHIQVYENGGSQPNVSSQFRLRYLVGGLSGVDEGLSSTENLKGFIEIIIPLLIECWVEAVPPQLATPVGNGIEREPLQVMQQVLNIISLLWKLSKQQDETHKLESWLRKNYLIDFKHHFMSRFPYALKEITKHKRKEPNKSIKHCTVFSNNIDHLLLNLTLSDIMVSLANASTLQKDCSWIEMIRKFVTETLEDGSRLNSKQLNRLLGVSWRLMQIQPNREDTETLIKAVYTLYQQRGLILPVRTLLLKFFSKIYQTEELRSCRFRYRSKVLSRWLAGLPLQLAHLGSRNPELSTQLIDMIHTAAARANKELLKSLQATALRIYDPQEGAVVVLPADPQQRLVQLVYFLPSLPADLLSRLSRCCIMGRLSSSLAAMLIGILHMRSSFSGWKYSAKDWLMSDVDYFSFLFSTLTGFSKEELTRLQSLRGVPHVIQTQLSPVLLYLTDLDQFLHHWDVTEAVFHSLLVIPARSQNFDILQSAISKHLVGLTVIPDSTAGCVFGVICKLLDHTCIVSETLLPFLASCCYSLLYFLLTIEKGEAEHLRKRDKLWGVCVSILALLPRVLRLMLQSLRVNRVGPEELPVVGQLLRLLLQHAPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFNVYITGHPQGPSALATVY
What is the function of this protein?
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.  Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit.
What are the official names of this protein?
Testis-expressed protein 10.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.
Protein: ROP1A_HUMAN
Sequence: MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVALCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHVSRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE
What is the function of this protein?
Important for male fertility.  With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
What are the official names of this protein?
Ropporin-1A, Cancer/testis antigen 91, CT91, Rhophilin-associated protein 1A.
What is the protein family that this protein belongs to?
Belongs to the ropporin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.
Protein: FRDC_ESCF3
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPL7_ARATH
Sequence: MSSLSQSPPPPEMDIQPPALVNDDPSTYSSALWDWGDLLDFAADERLLVDQIHFPPVLSPPLPPLIPTQTPAESELDPSPEESGSGSDRVRKRDPRLICSNFIEGMLPCSCPELDQKLEDAELPKKKRVRGGSGVARCQVPDCEADISELKGYHKRHRVCLRCATASFVVLDGENKRYCQQCGKFHLLPDFDEGKRSCRRKLERHNNRRKRKPVDKGGVAAEQQQVLSQNDNSVIDVEDGKDITCSSDQRAEEEPSLIFEDRHITTQGSVPFTRSINADNFVSVTGSGEAQPDEGMNDTKFERSPSNGDNKSAYSTVCPTGRISFKLYDWNPAEFPRRLRHQIFQWLANMPVELEGYIRPGCTILTVFIAMPEIMWAKLSKDPVAYLDEFILKPGKMLFGRGSMTVYLNNMIFRLIKGGTTLKRVDVKLESPKLQFVYPTCFEAGKPIELVVCGQNLLQPKCRFLVSFSGKYLPHNYSVVPAPDQDGKRSCNNKFYKINIVNSDPSLFGPAFVEVENESGLSNFIPLIIGDAAVCSEMKLIEQKFNATLFPEGQEVTACSSLTCCCRDFGERQSTFSGLLLDIAWSVKVPSAERTEQPVNRCQIKRYNRVLNYLIQNNSASILGNVLHNLETLVKKMEPDSLVHCTCDCDVRLLHENMDLASDIHRKHQSPIESKVNPPSSGCCCVSSQKDIPSRILNFNKDPEAGLDCKERIQADCSPDSGGKETDPLLNKEVVMNVNDIGDWPRKSCIKTHSALAFRSRQTMFLIATFAVCFAVCAVLYHPNKVTQLAVAIRMRLVHKI
What is the function of this protein?
Transcription factor that participates in reprogramming global gene expression during copper deficiency in order to improve the metal uptake and prioritize its distribution to copper proteins of major importance (Probable).  Binds directly to 5'-GTAC-3' motifs in the microRNA (miRNA) promoter of the stress-responsive miRNAs miR398b and miR398c to activate their transcription.  During copper deficiency, activates the copper transporters COPT1 and COPT2, and the copper chaperone CCH, directly or indirectly via miRNAs.  Required for the expression of the miRNAs miR397, miR408 and miR857 (PubMed:19122104).  Acts coordinately with HY5 to regulate miR408 and its target genes in response to changes in light and copper conditions (PubMed:25516599).  Activates miR857 and its target genes in response to low copper conditions (PubMed:26511915).  Involved in cadmium stress response by regulating miR397a, miR398b, miR398c and miR857 (PubMed:27352843).  Required for iron homeostasis during copper deficiency (PubMed:22374396).
What are the official names of this protein?
Squamosa promoter-binding-like protein 7.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Nuclear localization with a speckled distribution pattern.
Protein: PYRE_RUTMC
Sequence: MKQYQKDFVDFMLGSGALKFGEFTLKSGRVSPYFFNTGAFNTGQHLSQLGKFYATAIENSILDFDVLFGLAYKGIPLVTATTIALNDGFSKNVPYSFNRKEVKIHGEGGDIVGHQLEGNILIIDDVITVGTAIIEAMSIIKANGATAKGVIVAVDRQEKGKGEQSTIQEVEQNFGLSVLSIINLSHLVDYLKQGNDHALIERIEVYRDCYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: WNT4_DROME
Sequence: MPSPTGVFVLMILTHLSFGLGQVRNEDQLLMVGQNGDLDSSNPAIHHQQHQQHQQHQQHQQHQSNHNLNNGNMNSTILNTLMGNNAGQVVNSSPGGGGSMINQLGSSTSSVPSVIGGGVGSVGNPWHSAVGLGVPGNGMGLPSSHGLGGNMGSHPHGHALAGLAKLGIIVPGGQGLPGNLGYGGTMLNGGGVGGAAGMGLGIGSNTNNMDMQQGLYNEHFISEHTVMAVFTSQGQVGGPCRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAVTKDRQCLHPDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK
What is the function of this protein?
Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus.  Acts downstream of homeotic complex genes in the visceral mesoderm and is required for embryonic segmentation.  Also required for cell movement and FAK regulation during ovarian morphogenesis.
What are the official names of this protein?
Protein Wnt-4, dWnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: YIDD_METFK
Sequence: MLARLLVGLIKLYQWTLSPLLGQRCRFYPTCSQYAVEAIQKHGAWRGAFFTICRLSKCHPWHDGGHDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS3A_ARCFU
Sequence: MARKRRAARVKDKWTLKKWFTLIAPEYFGMAELGETPADDASKVVGRTVETTLAELTNDYSNQNTYKKLIFKVYRVAGDNAYTKFWRFELTREYLNSLTRRRTSKIEDIVDVTTADGYKLRVKSVVFTVRRCKTSQKRAIRAIMRQIVVEKASSLNFVQFLQECVLGKVPAEIYKNAKKIYPIRRVEIRKIELLAEPAEAETQPAVAEAVA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: Y179_THEAC
Sequence: MIVVTGMPGAGKDEFVKVARSLGFIDLHMGNTVREFAKNAGIPEIDHEIGNFATSERKKYGMDIWAVRTAQKITDDGRTVIDGLRNYEELQYFSKFSENPYVVAIFASRKDRFSRILKRDRPDDIRTMEELIERDTRELSWGIGNVIALADYMIVNDDTLETFHARCRKLLTEKFSISNKI
What are the official names of this protein?
UPF0200 protein Ta0179.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: TUSA_PSEP1
Sequence: MTDFTPDAILDATGLNCPEPVMMLHQHVRNLAAGGLLKVIATDPSTRRDIPKFCNFLGHELLQQQEDAGTFLYWIRKKAD
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SOFH_NAJAT
Sequence: DCCHNTQLPFIYKTCPEGCNL
What is the function of this protein?
Has hemolytic activity under low-lecithin conditions (PubMed:17277458).  Has low cytotoxic activity (By similarity).  Inhibits the expression of VEGF and bFGF in human non-small-cell lung cancer cell line NCI-H1299 in a dose-dependent manner (PubMed:17277458).
What are the official names of this protein?
Cardiotoxin-like basic polypeptide ah, CLBPah.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: DNAK_LAWIP
Sequence: MGKIIGIDLGTTNSCVYVMEGKEPKCITNPNGGRTTPSVVAFTDKDRLVGDAAKRQAITNSARTIFAVKRLMGRRADSPEVVHWKEHAPYKIVAASNGDAAVEIDGREYSPQEISAIILSKLKADAEAYLGESVSEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAASLAYGFDKKANEKIAVFDLGGGTFDVSILEVGDSVVEVLATNGDTFLGGEDFDQRIINYLVEEFKKEQGIDLSKDNMALQRLKDSAENAKKELSTAMETEINLPFITADQSGPKHLLIKLTRAKLEQLVMDLVGRTIEPCSKALEDAGLQTSNIDEVILVGGMTRMPLVQKKVAEFFGKEPNRSVNPDEVVAMGAAIQGGILAGDVKDVLLLDVTPLSLGIETMGGVFTKLIDRNTTIPTRKSQTFTTAADNQPSVSIHVLQGERPMASDNMTLARFDLTGIPPAPRGVPQIEVAFNIDANGIVNVSAKDLGTGKEQSIQITASSGLSEADIEKLIREAESHASEDKKKQEIIEVRNHADGLIYSTEKSIKDLEGKIDAELQADITSKIEALKKVMEGEDSAAIKKATDELASASHKLAEQLYKQTQETSGASGDPTDTSASSSKSGDDVVDADFTEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ARL13_CHLRE
Sequence: MFGLLVNFYRFCRKKTERKITIALLGLDNAGKTTLLNSIQGEVDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEARKKKEREERLRKQREERLRQQKEEEERAREVEKENELHDGKAPSLLAAGGGVVGAAAAGVNGVMVDEQQELRPPGQHQEAPEALGLHNGLALGLPHTIESPGKFPPPPRRPLEAHPASDLRLVAPDQGVSSASGGPGLGAMPSGSHGGGGVPPQPASLPHVRAALPPLPPSAPQPSDAGVGSSGSASRHPGAHSSSAAAPPNVASGAAAEDGPEPDAAGTAAGEAGSGSVFAPRPASAGGGGPGSRGSGSGMTPDARELGSGGVESGEGTPARLRAGAQQASDGGHGNSKGSFSLVHTSNKVVPVAPDLRAGIPGAPNDA
What is the function of this protein?
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure.  May act by maintaining the association between IFT subcomplexes A and B (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 13B, CrArl13B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane.