PharMolix/UniProtQA huggingface dataset:
Protein: PPK1_ECOLI
Sequence: MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEMARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVEIIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVLREKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVVRYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQNSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGMCSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEVATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIKSLEQPE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).  Can form linear polymers of orthophosphate with chain lengths up to 1000 or more.  Can use GTP instead of ATP, but the efficiency of GTP is 5% that of ATP.  Also exhibits several other enzymatic activities, which include: ATP synthesis from polyP in the presence of excess ADP, general nucleoside-diphosphate kinase activity, linear guanosine 5'-tetraphosphate (ppppG) synthesis and autophosphorylation.
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Associated with the outer membrane in overproducing cells.
Protein: POLS_CHIKS
Sequence: MEFIPTQTFYNRRYQPRPWTPRPTIQVIRPRPRPQRQAGQLAQLISAVNKLTMRAVPQQKPRRNRKNKKQKQKQQAPQNNTNQKKQPPKKKPAQKKKKPGRRERMCMKIENDCIFEVKHEGKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKRSSKYDLECAQIPVHMKSDASKFTHEKPEGYYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTALSVVTWNKDIVTKITPEGAEEWSLAIPVMCLLANTTFPCSQPPCIPCCYEKEPEETLRMLEDNVMRPGYYQLLQASLTCSPHRQRRSTKDNFNVYKATRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIGTDDSHDWTKLRYMDNHIPADAGRAGLFVRTSAPCTITGTMGHFILARCPKGETLTVGFTDSRKISHSCTHPFHHDPPVIGREKFHSRPQHGKELPCSTYVQSNAATAEEIEVHMPPDTPDRTLLSQQSGNVKITVNGRTVRYKCNCGGSNEGLITTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKIHIPFPLANVTCMVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRSMGEEPNYQEEWVTHKKEVVLTVPTEGLEVTWGNNEPYKYWPQLSANGTAHGHPHEIILYYYELYPTMTVVVVSVASFILLSMVGMAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVLCNCLRLLPCCCKTLAFLAVMSIGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKNLPDYSCKVFTGVYPFMWGGAYCFCDAENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNITVTAYANGDHAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESKDVYANTQLVLQRPAAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNCAVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGVAIIKYAVSKKGKCAVHSMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDISATAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What is the protein family that this protein belongs to?
Belongs to the alphavirus structural polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: NADK_BURCM
Sequence: MKTGNQFNTVALVGRSNTPGIAEPLTTLAGCIAKLGFEVVFEVDTAREIGISGYPALTPAEIGARADVAVVLGGDGTMLGIGRQLAPYKTPLIGINHGRLGFITDIAAADMQARVPVILSGKFEREERSLLEARIVRDGEPIYHALAFNDVVVNRSGFSGMVELRASVDGRFMYNQRSDGLIVATPTGSTAYALSSAGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIVGGRDVNVNFDMQSFTALELNDTIEVRRSKHTVPFLHPVGYSYYATLRKKLHWNEHASNEDDTAS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_PORG3
Sequence: MIIEELHIVNFKSIAAADCRFSPKVNCLVGNNGMGKTNLLDALHFLSFCRSHLSVPDNMVVRHGEEMALLQGLYRDESGDGIELLLSIRPGKHKVLRRNKKEYERLSDHIGHFPLVIVSPQDYQLILGGSDERRRFMDQQLCQQDPRYLSALIQYNRHLQQRNTMLKQDRHDDALMDVLELQMGSYAAEIYNKRSRFIEDFLPVFNDLYSDISGSAEKVSLSYRSHLADGIPLEELLRRSRPKDYLLGFSSCGVHKDELEMLLGGVLIRKIGSEGQNKTFLISMKLAQFRHQQLHGDETPILLLDDIFDKLDATRVERIIRLVGGNGFGQIFITDTNRKNLDEIIASWSEDYRLFEIENGQIFQ
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_PSE14
Sequence: MTMLKDPSKKYRAFPTIDLPDRTWPSKTIDAAPIWCSSDLRDGNQSLIEPMDAAKKLRFWKTLVSVGVKEIEASFPSASQTDFDFVRTLIEDGHIPDDTTIQVLTQAREDLIARTFESLRGAKKAIVHLYNATSPSFRRIVFNQDKAGVKEIAVNAAKLFVKYAAQQPETQWTFEYSPETFSATELEFAKEVCDAVIEVWNPTPENKVILNLPATVEVATPNIYADQIEWFGRNITRRDSVLISLHTHNDRGTGVAATELGLMAGADRVEGCLFGNGERTGNVDLVTVALNLYTQGIDPELDFSDIDGVRKVVEECNQIPVHPRHPYVGDLVHTAFSGSHQDAIRKGFTQQKDGELWEVPYLPIDPADIGRSYEAVIRVNSQSGKGGITYLLEQEYGISLPRRMQIEFSQVVQGETDRLGLEMSAQQIHSLLRREYLQANTPYALISHKLQEENGNSAVDAEVHVDGETQHWRGKGKGALEALVAGLPVAVEIMDYNEHAIGSGTTAKAAAYIELRVNGERAVHGVGIDENITTASFRALFSALNRSLSQTQAKAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: AROE_PSEA7
Sequence: MDRYCVFGNPIGHSKSPLIHRLFAEQTGQALAYEAQLAPLDDFAGFARRFFEQGKGANVTVPFKEEAYRLVDELSERATRAGAVNTLVRLDGGRLRGDNTDGAGLLRDLTVNAGVQLRDRRVLLLGAGGAVRGVLAPFLGERPAQLLVANRTAEKAVALAGEFADLGAVRGCGFADVEGPFDLIVNGTSASLAGDVPPLAESVIERGRTVCYDMMYAKEATAFNRWAAERGAARTLDGLGMLVEQAAEAFFLWRGVRPASAPVLETLRRQLATG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NAR1_CHAGB
Sequence: MSAILSADDLNDFISPGVACIKPIETLPTQPGPEQSQQPQSLEFEVILDGQQPTTGSSSNGTTPPAQISLTDCLACSGCVTSAEAVLVSLQSHNEVLTLLDAAPALRVIQDSDGKPVVSGLENPEAKLFVASVSPQTRASLAAACGGAVTEQQAGWMIEQLLMGPAGLAGGGKHGNGFTWVVDTNTAREACLMLGSDEVLGGGSWGGSDKPTSPILTSSCPGWVCYAEKTHPYVLPHLSRVKSPQALMGTLLKTTLSRVLGIAPDRVWHLAVMPCFDKKLEASREELTDTAWGSGGVPGRGVRDVDCVITSKEILMLAASKGVDFFGLAKSAPVKQPMFPDSDIHRFLFPAQRRKQLRDGGTSGGNLHYIIQDVLSKHAGSQIQMTRGRNADVVEFAVLSSSGETIFKAARYYGFRNIQNLVRKLKPAKASRMPGGKPFGSARRPAGKSATLEHSYVEVMACPGGCTNGGGQIKVDDQVVIDRKNFGEKPGPDEQKAWQAEVDEAYFSGDESDPAQGAGDDQSMELIAGISPSYIRDTLAHWADITGIQLDKLVYTSYREVVSDVGKPISDTERVVQLAGKIGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: SCAM4_ARATH
Sequence: MNRHHDPNPFDEDEEIVNPFSKGGGRVPAASRPVEYGQSLDATVDIPLDNMNDSSQKQRKLADWEAELRKKEMDIKRREEAIAKFGVQIDDKNWPPFFPIIHHDIAKEIPVHAQKLQYLAFASWLGIVLCLVFNVIATMVCWIKGGGVKIFFLATIYALIGCPLSYVLWYRPLYRAMRTDSALKFGWFFFTYLIHIGFCIVAAIAPPIFFHGKSLTGVLAAIDVISDSLLAGIFYFIGFGLFCLESLLSLWVLQKIYLYFRGNK
What is the function of this protein?
Probably involved in membrane trafficking.
What are the official names of this protein?
Secretory carrier-associated membrane protein 4, Secretory carrier membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Protein: MMPS1_MYCTU
Sequence: MFGVAKRFWIPMVIVIVVAVAAVTVSRLHSVFGSHQHAPDTGNLDPIIAFYPKHVLYEVFGPPGTVASINYLDADAQPHEVVNAAVPWSFTIVTTLTAVVANVVARGDGASLGCRITVNEVIREERIVNAYHAHTSCLVKSA
What are the official names of this protein?
Probable transport accessory protein MmpS1.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INVS_DANRE
Sequence: MAMLLPQNPSQVHAAAVNGDKNTLHKLITESALRDSEDQFGRTPLMYCVLADRLDCAEVLLKAGAGINKTDHSQRTALHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLKHMAPGEVDTQDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGIPDSEGKIPLHWAAHNKHPNATRTVRCILEAAPTESLLNWQDYEGRTPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLERNKSGMIPSDSQGATPLHYGAQSNFADTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDLKKDIDINMTDKYGGTALHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQHDADPNIQDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQELTQFLLEHGALSIAAIQDIAASSIQALYKGYKVRRAFRERKKLLMRHEQLRKDAAKKREEERRREAEQQLSFAEAGQKQRVLLAAVGVEKLSLDEAEQRVKDSVAAKGHKHKKSSSAHNSQSRREKPSRAERRTREPETSDAPSIRSLPPVTPMSTKKCPVTREEVCVRETFGPDTGISLNCGSANERRSPAGSSRPGSAKPVHTGTHVAPGHMETTPTPKPRPSTTGAHSKNASQDTPQHNETQTTSKGNKPISEHKPTGSQPSNNTSVTRQKEKRQEKETHREKDKRSRTEGDKQTVREKQKGTGIERAKERLMGRTRKKLAEKEKEKKKDGTCSKNQAAVVIQRAWRRSCVRGRIRKVLCRSLKGVESAEATALLIQLLWEWPVLHDHTHRKPSDVQAPPTRIAGKKSSVLQNIYGAAPSKRGTSLRAAALKTQSQSQSQVLLDLSLRTHKQLSAVECVNLVDSVSQAKQFSYHLRPSSGASQSSQN
What is the function of this protein?
Required for normal renal development and establishment of left-right axis.  Probably acts as a molecular switch between different Wnt signaling pathways.  Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome.  This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling.
What are the official names of this protein?
Inversin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the cytoskeleton.
Protein: SYT_FRATM
Sequence: MINIRFPDGSIREFEAGVNSLDVAKSISPSLAKATMAAYIDDQLKDAKDAINSNCELRLITVKDPEGLEILRHSCAHLLAHAVKELYPNTEVTIGPVVDNGFYYDFSFKESIGEADLPTIEKKMKELAKKSAPVSYRVVPKAEAIEFFKAQGENYKVEIIDSIADEQMKIYTQDNFSDLCRGPHIPNTSVLKAFKLTKLAGAYWRGNSDNEMLTRIYGTCWATKEDLEQYLNMLEEAEKRDHRKIGKVLDLFHFQEDSPGIAFWHDNGVRIWRQVEDYMRASNNKYGCSEIRTPLIADFSLWQKSGHASKYAENMFATKSENRDFAIRPMNCPTCVQVYNTKLHSYRDLPIRMAEFGIVHRNEPSGSLHGLLRVRSFTQDDGHIFCTPEQVEEEVILMVQQCFEVYKDFGFNDFAVKIALRPENRIGDDETWDKSEQMLKNALDANNVSYELLPGEGAFYGPKIEFHLKDAIGRSWQCGTIQLDFSMPQRLGATYIDKNGEKQVPVMLHRAIVGSLERFIGMLIEHYAGNLPLWLAPVQVAVMGISNNQDDYCKEVFIMLEKNGIRAKLDLRNEKIGFKIREHTLLRVPYLVILGKNEQEQKIITIRKHSGEDLGQMSVDDFCAFLDKQIQAKE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_RHOPS
Sequence: MSAVPLKNDGAAHAGVRTISVLGATGSIGDSTMDLLRAAPEKYRVESLTGNANVAGLAKLAKEFSAKFVAVADPARLGELRAALADTEIACGAGESAVIEAASRPADWVMAAISGAAGLKPALAAVDRGATVALANKECLVCAGDFFMSRAVAAGARILPADSEHNALFQALASGNRHELTRVIITASGGPFRTWAAADIEQATLAQALKHPNWSMGQKITIDSASMMNKGLEVIEASYLFALSPDEIDVLVHPQSIVHGLVEFADHSVVAQLGAPDMRIPIAHCLGWPDRIAGRAARLDLAKIGQLTFEAPDFVRFPGLRLAYDALRTGNGATTVYNAANEIAVAAFIAQKIRFGAIARLVEDTLNGWVRAGNLAPLSSADDAIAVDHNARKMAATLLPQIAAKAS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: Y373_NITEC
Sequence: MLLTIDNVLTEEELAAASSLLAESAWVSGLVTAGAQAAKVKNNQQLPEDSPQMAALRGLVLGALNRNALFFTATLPKKIMPPFFNRYSGKTNHYGFHVDNAMRMLPDGVGYVRADVSATLFLSNPQTYDGGELVINDTFGQQSVKLQAGSMVIYPSSSVHQVTPVTHGERIACFMFIQSMVRDPNQRRLLYEMDMALLQLRQNIGETEAVVSLTGTYHNLLRQWAES
What are the official names of this protein?
PKHD-type hydroxylase Neut_0373.
Protein: FABH_MYCA1
Sequence: MKQISATSGPTNIGLLSVGSYRPQRAVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDESTASMATEAGREAIAKAGLEASDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISAGCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTDRSNCFIFADGAAGVVVGETPTQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQAMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGYGAGLSYAAQVVRLPPG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL823_MIMIV
Sequence: MGSYYSTESTKSNESNETTNNVEGIVDTIGGTVESINSDGIITTSENIVEIVLKENNQPTIFETQESNILEIVTTKIDVLKKILRLIGEVTSECQFSFQNVNEGGRIIVTELHDNKTILLKLVLKGTGFDFYKCSKSKITARLYLPDIDEALGLIGVDDTNTNPIIISMKKDKETSIFITRIDNSGFTEQVELPCRESVGLNIPLPKTTFQGKIVINAEKFRKICERICSVSDLIKISLTDKEVSFSARYYNLDFRYKHSVESKVLGQTIENYFFIDGMLKFIKYFQSSDEISIYIKKDFPLVIHGPFDNFGSIYVFTSPIEE
What are the official names of this protein?
Uncharacterized protein L823.
Protein: HIS3_STUS1
Sequence: MNWLDEINWNADGLVPAIAQDHKTGRVLMMAWMNREALQLTAQENRAIYWSRSRGKLWRKGEESGHVQQLHELRLDCDADVIILMVEQIGGIACHTGRESCFYRVFENGAWKVVEPVLKDPHAIYAEHKHE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
Protein: ISPF_SYNY3
Sequence: MTALRIGNGYDIHRLVGDRPLILGGVTIAHHLGLDGHSDADVLTHALMDALLGALSLGDIGHYFPPSDARWQGADSLKLLAQVHQLILERGWRINNLDNVIVAEQPKLKPHIQAMKENLAKVLTIDPDLIGIKATTNERLGPTGREEGIAAYSVALLIKEG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: YKN4_SCHPO
Sequence: MIAAVEKDAVPRKRRVISQVSQACIRCRQKKIKCSGEKPSCQACSNNKVECIWPDRPNMRGKKPSSAARTLSPLTGIVQPYLGSHPFSPTILSPSSPNMDFTYSINSFGDYQKQLRLPTSRKLLQLWDIFLKTSYTELFGIFNKAQITSQIASDTAPPVLVLCICAHAARFSQEEVNRFKSSTAASDYYANQAFSLLPCRFQDISLTNITCLLLLCLIELGSCRGAKAWLLLGMALRMVDSLDLGNEINDNPLTMGSNTVSWTEAEQKRRVYWACFFVERLLSTGYMAPSKLRSLSLSLQKTSIQLPCPEPNFLFNQPILTELFDGSLPENTQSDTTSMAPYQRSLQLEFMTGSLIRLSNLWSEISRWALCGGYTKDITPPWLNQSQFHRSFELLKAWHENLPPRAVWSYTNYSAYSSPGESAGACYTFMHLLYHTTLTYLLRNVLDLFPEKSRQKSKLFSSVSQRFGQQPPTVWMDMILDQVITSADFITKLSKDPLNYIMSPFVGFSILTAATIHMLLKFCVVNIDQNYISSSRLVHVDHQILQDRSKYWKINQAMLVTLQRLYNFYRFQYLEEQSLYNFKIPGFPLCILEYGIVEDQSMKSNPDLNSFSKELFSRGTNELLNNGDDTQSGNSTPAMGVSEIRTDTILDEEVPVDPLITSILDDGRWWEEMFGSERKAGFKETVFEDMNGRSIRL
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein PB1A11.04c.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: MTNN_ACTPJ
Sequence: MRLKIGIIGAMAQEVEILRNLMVEAKVIKMAGCKIYDGKINNTKVALLQSGIGKVSAAIGTTLLLELTKPDMVINTGSAGGLDANLNVGDIVISTEVRHHDADVTAFGYEKGQLPANPAAFLPNEQLVSVALKETQTAGFNAVSGLICSGDVFVNGAEKIAQIRQDFPNVAAVEMEAAAIAQVCHAFNVPFVVVRAISDVADKESHLSFDEFLPLAAKNSSEIVVAMLNNFA
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: YN146_YEAST
Sequence: MISVCFVFPHSLALDFKSRCKKNRTKLCSAYYVSQVLRICKEMPYRDLILFSTVRKGVYMRLYY
What are the official names of this protein?
Uncharacterized protein YNL146C-A.
Protein: LPXB_DESPS
Sequence: MDKQKRETGSEIMVVTGEASGDIHGANLVRALKEKDSSLSFSGMGGPELASLGVEILYDAKKISVVGLVEVFSHLPSIFAAKKILQRRLKNKPPALLIIIDLPDFNLMLAKKAKALGIPVFYYITPQVWAWRSGRIKTIGERTDQLGVILPFEEEFFRQRGQAASYVGHPLLDNVSIKLSREEFLTKHRIGPAAKYVGLLPGSREKEISALLPDFLRAAKRLQDECSEKISFLLPIAATIDREQLLENGLAEYQDLLDIHVISEDRYELMACCDAVVAASGTVTLELAILEVPMLVVYRTSPISYWVGRKLVKIEFFSLVNLIAGREVVTELLQDEVTPERISIEIKELLYGAKGVAVGKGLREVHGLLGEAGASAKAADLALSMI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ATPG_LACAC
Sequence: MPASLLELKRKIASVKQTGKITEAMRMVSASKLNQTENRDKDYTVYNDHVRKTISHLISSQVVDSLRERDISIDKNNISKIDYTDVFGLGITADMIQPRKNIKTTGFLVVTGDRGLVGSYNSSVIKNMMSIFDDERAQGREVKVLAVGSVGAQFFKKNNVNVVYEKDGVSDVPTFDEVLPIVSTAIKMFLNGVYDQLYVCYTHHVNSLSSAFRVEKMLPIVDLDIGVKEAEAHKELEYDIEPDVNSVLMKLLPQYARSTIYGAILDAKTAEHASSMTAMQSATDNANDLVSNLTTKLNRARQAQITTEITEIISGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSAE_PROMM
Sequence: MAISKGDKVRIRREESYWHNEVGTVASVDTTGKYGVLVRFEKTNYFGMQGTDNGNLTNSFAESELDRA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: YR514_MIMIV
Sequence: MNKVNINFSLKSLPTDLLNHMNYYDNGSTNVKCTLQSFKNTLEHNLLLINKLIEESENITNVLCHPNNILLEFNSNNVMNKLINDGTVKIINDNYDGTDDDLIPLVDLSEEETNQDRLNRIINMTNRDNSGGLFGASDDDEEEISDDDLLLHDLLGNQNDTSSIFNKYTNLIGNVIDNSDNSSDSDDSDSLDGSDDLNDSDNVDNLFVG
What are the official names of this protein?
Uncharacterized protein R514.
Protein: KCNS1_COLGU
Sequence: MLMLLVRGTRYESLRSKVVLPTPLGGRGTEVLVSESPSPDTGIRWRQSDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAASEEQARRLCDDYDAAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENVLAACCRARYLERRLTQPRAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGTGGKELGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSVDEVSEASLETSREISQEGRSADLETQAPSEPPHPQMY
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 1, Delayed-rectifier K(+) channel alpha subunit 1, Voltage-gated potassium channel subunit Kv9.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.