PharMolix/UniProtQA huggingface dataset:
Protein: PLPL_EMENI
Sequence: MEKSAAGDNIDKYSPSSIPDYDTEFLNPDDLRAFEKALTDQDADPLVALNDWRPVYQRVVRRGRGRRKSAAAAPRRTKDETREGVLYTVLKWPFLLFVLGWITFLSVGYALTRIYIFLYEQWVTWRGKRESLRRELYKHENYDDWLHAAQALDEYLGNQRWKKIDEYAYYDHLTIRKLGRQLRTVRMQVEEEMKRGESGSTVVVEELCNLLEACVKANFAGVENPRLYSEAYSGTKDLVQDYIDEVHACVKVITDSRQARNEEKYSHFKHLDTNFGRTALCLSGGATFAYYHFGVVRALLDNEVLPSIITGTSGGALVAALVGTRTDDELKQLLVPALAHKIKACSEGFTTWARRWWRTGARFDTMDWARQCSWFCRGSTTFREAYERTGRILNVSCVPSDPHSPTILANYLTSPNCVIWSAVLASAAVPGILNPVVLMTKKRDGTLAPYSFGHKWKDGSLRTDIPIKALNLHFNVNFTIVSQVNPHINLFFFSSRGAVGRPVTHRKGRGWRGGFLGSAIEQYIKLDLNKWLKVLRHLELLPRPLGQDWSEIWLQKFSGTVTIWPKTVPSDFYHILSDPSPERLARMLRTGQQSTFPKIQFIKNRLKIEYAILEGLHRFSADGESVGATSIQPFPFDNGAAGADQKSNDPREERLNRNFPERSSEYSYDYVKSFSDFSDDPIVSAENSSVDDNYIVPSRQRDAGAEAGVGTGTAERRGSFSSLFNLEEMRRQSAVFFDDPDLYRDGGDL
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein AN0408.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HBB2_TORMA
Sequence: VSLTDEEKHLIQHIWSNVNVVEITAKALERVFYVYPWTTRLFTSFNHNFKASDKGVHDHAVNVSKALSAAIGDLHNVNKNFSALSTKHQKKLGVDTSNFMLLGQAFLVELAAFEKDKFTPQYHKAALKLFEVVTEALSCQYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL22_CERSK
Sequence: MGKEKNPRRVGENEAFAKVKMLRTSPQKLNLVAALIRGKKVDKAIADLTFSKKRISQDVLKCLQSAIANAENNHGLDVDELVVSEAFCGKNLVMKRGRPRARGRFGKIMKPFSELTIKVKQVGETA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SEM2_CAEEL
Sequence: MDLQKPPNFMLDCGMAPHMMPPINWAAAAIAVASSTSGATNATSSNSVATSQQLQHHPYGTAAGGYKHAQQAIPKSVTPYSDATNCKKSSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAERLRVCHMQEYPDYKYKPRKKPKKNPDGTLQQPAQPQAPQQQQAPPRGASPQARQRKRPNTDQQSETQQFQNFKSVKVEQDWMGNAHMSHAQKMPFHPSYPSPSEFGHAPLTPESGFYDDYFTQQHHQQHFASQHHNSAGSPLRMTNLGMDMGMPPQMMGHNSGFGAGNHPFYLHTSPPSVDQDDMRSLSSGSSGYADCSASEQSTSSPNSAGVVTMATAATTTTHLDDLEQICPTVTTGELVNYPWSDALGIDINFS
What is the function of this protein?
Probable transcription factor required for embryogenesis, vulval development and cell fate specification of the postembryonic mesoderm (also known as the M lineage) (PubMed:21307099).  Specifically, required for the specification of sex myoblast cells and their development into the muscles that are necessary for egg-laying (PubMed:21307099).  In addition, may be involved in RME GABAergic motor neuron progenitor cell fate specification (PubMed:26153233).
What are the official names of this protein?
Transcription factor sem-2, Sex muscle abnormal protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL33_CAMHC
Sequence: MAKNANRVKIGLKCSECGDINYTTYKNNKNTANKIELKKYCPRLKKHTVHKEIKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: OTC_PSYWF
Sequence: MSVRHFLTLLDLSPAELEALIKRASELRKMQHAGEVYQPFVGRTLGMIFEKSSTRTRISFETGMGQFGGHAIFLSPKDTQLGRGEPIEDSARVISSMVDIIMIRTFEHEKVEKFAQYSSVPIINALTDDFHPCQLLADMQTFYEHRGSIKDKIVTWVGDGNNMCSSFMAAANQFGFELRVAAPYGFEPNPELMEKFKHCVSLVDDVQDAAKDAHLIVTDVWASMGQESEQNTRARRFAPYQVTPSMLDKADPEVLFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLKDKIKLN
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_LACPL
Sequence: MAAKWEKKEGNQGELTFEIGADKISEGIDKAFQRTKKNLNVPGFRKGKVPRQIFNQMYGEEALYQDALNIVLPEAYEEAIKETEIEPVDQPQIDVDSMEKGKPWVLKAVVTVKPEVKLGQYKELSVTRQNTRVYAKDVDAELESRREKQAELVLKEDQPAAKGDTVVIDFKGFVDGEPFEGGESENYSLELGSNSFIPGFEDQLVGVKAGDETEVKVTFPKDYQAEDLQDKEATFKVTVHEVKTKELPELDDEFAKDVDEDVDTLEELKAKIKDELKEQKESAAHDAIEDEALNQAVDNAEIQAIPDAMKEDDIHRQMDQYLANMQQQGIDPKTYYKLTGTTEDDLHKQFAADAERRVKTNLVLEAVVEAENIKPSQDEIAAEVKDLASQYNMEESAVRGALTDDMLSHDIAIRQAVDLIADSAKQNAKAEDKKDDSDKN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NHAB_SHESM
Sequence: MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKMITKVRSKILVSLMFCLASAFLSAFLDALTVIAVIITVAVGFYSIYHKVASGKDFSADHDHTSEGKNEDGENQLNEEELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEFAIRMSPVTVPVLFAGILTCFLVEKLRWFGYGAQLPEAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGLALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYIANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLSIVGVMAIESGFLEQMTQYFYDSHAIIHHSVKEALAPAAAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMD_RALSO
Sequence: MPVAGPLEIVSLDNEARGVGRLSNEDGTPGKVVFVEGALPGERVTYRSHRAKPSYEQATLVDILRQSASRVTPQCRFFGTCGGCSMQHLDSRAQIAIKQRVLEDDLWHLAKLRPDVVFRPIAGPDWGYRYRARLTVRHVAAKGGVLVGFHERKSSYVADMTSCEVLPPHVSALLVPLRELVGRLSIVQRMPQIEVAVGQDVTALVLRILEPLTSADEAELRAFADRHAVQFWLQPKGPDTVYPFYPLDRALTYTLPEFGITMPFKPTDFTQVNHQINRVLMSRALKLLDARPGDRLLDLFCGIGNFTLPMATRGCEVMGIEGSEALTTRALANAQHNGLDGKTTFACRNLFEVSADDIAALGRFDRWLVDPPREGALAVSKAVAELSQRGGEAAALLPGRIVYVSCNPATLARDAGLLVHEAGYRLAGAGVVNMFPHTSHVESIAVFERA
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: NUOH_EDWI9
Sequence: MSVITPDTVEILLTVLKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPSRVGWGGSLQLVADMIKMFFKEDWVPPFTDRLIFTLAPMIAFCSLLLSFAIVPVAPGWMGADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMQVIVDSQTHLWNIIPQFFGFLTFIIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALIVTLFFGGWHGPWLPPFIWFAIKTAFFMVMFILVRASLPRPRYDQVMAFGWRICLPLTLINLLVTAAVILYHAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL36_PORG3
Sequence: MKVRASVKKRTPECKIVRRKGRLYVINKKNPKYKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DXR_CLOP1
Sequence: MKRISILGVTGSIGTQTLDVLRFHKEDFELVGITANRNIELTMDIIKEFSPKYVAINHEESYKKLVDLVKSQGLKCEVIYGMEGLVKVATLDEIDIVVTSVVGMIGLKPTVEAIRKGKDIALANKETLVVAGELVMREAKENGVKILPVDSEHSAIFQSLQGNAHNKIDKILLTASGGPFRGFTIEDLKSVTPERALKHPKWNMGQKISIDSSTLMNKGLEVIEAHWLFDCPYKDIEVVVHPQSIIHSMVQYTDGAVIAQLGVPDMKLPIQYALNYPNRQGNISEKLDLFKIRELTFEKPDLDTFKCLKLAYEAGEKGKLMPTILNGANEVCVELFLNKKITYLQIPEIIEECMNTFDYNKEVTLHNVINLDKEVRQYIYEKYN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CUTC_YERPB
Sequence: MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGLTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAMKSLLVMGSPLAKHT
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_MYCUA
Sequence: MASQKPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHDYDAQVAELAERGADVDATIRTVTTDDVRNACDVLAPRWEASGGVDGRVSIEVDPRLAHETDKTIQQAVELWKIVDRPNLLIKIPATKAGLPAIAAVLAEGISVNVTLIFSVDRHRGVMDAYLTGMEKAAQAGHDLSKIHSVASFFVSRVDTEIDNRLEQIGSAEALALRGQAGVANARLAYAAYQEVFEGDARYQALKERGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTLDAVADHGVVKGDSITGTSGDAQQVFDKLEAIGIDLSDVFDVLESEGVEKFEASWKELLDATQAQLDALAK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_RAT
Sequence: MSSCGACTCGAAAARLLTTSLTSAQRGISCGRIHVPVLGRLGTLDTQILRRAPLRTFSETPAYFASKDGTNKDGSGDGNKKSVTEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEVEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQGSQQMPQEKRGGEVLDSPHDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSGESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPSKESSEEDYDSGVEEDGWPRQADAANS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease complex.  Hydrolyzes ATP.  Targets specific substrates for degradation by the Clp complex.  Can perform chaperone functions in the absence of CLPP.  Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure.  ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis.  Important for efficient erythropoiesis through up-regulation of heme biosynthesis.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: UBA2B_ARATH
Sequence: MTKKRKLESESNETSEPTEKQQQQCEKEDPEIRNVDNQRDDDEQVVEQDTLKEMHEEEAKGEDNIEAETSSGSGNQGNEDDDEEEPIEDLLEPFSKDQLLILLKEAAERHRDVANRIRIVADEDLVHRKIFVHGLGWDTKADSLIDAFKQYGEIEDCKCVVDKVSGQSKGYGFILFKSRSGARNALKQPQKKIGTRMTACQLASIGPVQGNPVVAPAQHFNPENVQRKIYVSNVSADIDPQKLLEFFSRFGEIEEGPLGLDKATGRPKGFALFVYRSLESAKKALEEPHKTFEGHVLHCHKANDGPKQVKQHQHNHNSHNQNSRYQRNDNNGYGAPGGHGHFIAGNNQAVQAFNPAIGQALTALLASQGAGLGLNQAFGQALLGTLGTASPGAVGGMPSGYGTQANISPGVYPGYGAQAGYQGGYQTQQPGQGGAGRGQHGAGYGGPYMGR
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus.  Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs.  May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity).
What are the official names of this protein?
UBP1-associated protein 2B.
Protein: MEU23_SCHPO
Sequence: MPNTESELNEEFSNEFNIPPPTESSSKEGNRFLNDFRVEFEKRRIEARNRILESEGRALENKTHLNEEEIRTNERVKRFQRRVDEWTALEIERESQVQPPLWYQRDREEQNRTLNFLMSGMADLQRTINTMQGTMNTMQGTMNTMQENMINFTNKVNTLDMRSVRAENRDLRKGAYVISPVPFINGNNPDPDLPPITSVQDVDRLSRSQCSRYLQGYGVTFHVNETIGMKKKLASAVGLSAEYDREYPFSGFPN
What are the official names of this protein?
Meiotic expression up-regulated protein 23.
What is the protein family that this protein belongs to?
Belongs to the UPF0612 family.
Protein: RM34_YEAST
Sequence: MPLFARLCQPQSRRMFSSISSFSALSVLRPQTGMLLNSSPLKTPSFTPLGFGLIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWFLSH
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L34, mitochondrial, L34mt, Mitochondrial large ribosomal subunit protein bL34m.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: PSBC_CHLRE
Sequence: METLFNGTLTVGGRDQETTGFAWWSGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVSHFVPEKPMYEQGLILLPHIATLGYGVGPGGEIIDTFPYFVSGVLHLISSAVLGFGGVYHSLIGPETLEESYPFFGYVWKDKNKMTNILGYHLIMLGLGAWLLVWKAMYFGGVYDTWAPGGGDVRVITNPTTNAAVIFGYLVKSPFGGDGWICSVDNMEDIIGGHIWIGTLEILGGIWHIYTTPWPWARRAFVWSGEAYLSYSLGAIGVMGFIACCMSWFNNTAYPSEFYGPTGPEASQSQAFTFLVRDQRLGANVASAQGPTGLGKYLMRSPTGEIIFGGETMRFWDFRGPWLEPLRGPNGLDLNKLKNDIQPWQERRAAEYMTHAPLGSLNSVGGVATEINAVNFVSPRSWLACSHFCLGFFFFIGHLWHAGRARAAAAGFEKGIDRFDEPVLSMRPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43, Protein P6.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: IHFB_GRABC
Sequence: MTKSELIASLKADNPHLTERDVETIVSTIFDEISNALARGARVELRGFGAFTIKRRDARVGRNPRTGETVSVDEKVVPFFKAGKELRERVNNGTRKNGGSADAASGG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RPOC_EHRCR
Sequence: MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYRGVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVISESAYNQAKDNYGEDSFLALTGAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILTVIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQEAVDALFDSTRRSYVSNKAGSVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANKMIQNEKPEVWDILDEVIHEHPILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLEARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALHNKDVHLCSQIKYRMTYCNYDTSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQVLTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQSGISFGCKDMIIPDTKTMHVDNASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYMMAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVAAVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRSPLTCEAKKGICALCYGRDLAIGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSNIVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYTMPIITEKTGIIKYMDLIDGVSINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDNDNIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPRDSIKTRDITGGLPRVIELFEARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFVHKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKVEIFEPGDTMYLVGENIDMEEVIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAASFQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFLMNKIKKLSLLNKEDYSMYYNNEYQDSALLQNDNNAFNQELHKDTGNIVDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ENGB_ANAPZ
Sequence: MLGCRFVAGVQDRKSFPDFGVPEVAFAGRSNVGKSSLINAITNNKKNAKTSSNPGSTRQINFYLNKGIVALVDLPGYGYSKASKEATRGYLDVMEHYLMSREALQRLVLLIDSRIGLKEIDRDFLCWLEEHGIYYSIVLTKADKLSEQALGSMVSFVQNQAQGGNFLLQPIMWVSSKSGRGIRELAHEISRCI
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ARGC_RHIME
Sequence: MKPKIFIDGEHGTTGLQIRVRMAGRTDLELLSIPEAERRNAAMREDLLNSADIAILCLPDDASREAVAMVAGNNRVRIIDTSTAHRVAPDWAYGFAEMDKAQPQRIRDARHVANPGCYPTGAIALIRPLRQAGILPDGYPVTVNAVSGYTGGGKQMIAQMEDDQNPDHIGAPHFLYGLTLKHKHVPEMKMHGLLERAPVFSPSVGKFAQGMIVQVPLYLEDLAAGATLETIHRALVDHYAGQSIVEVVPLDESAKLARIDATELAGSDAMKLFVFGTKGGAHVNLVALLDNLGKGASGAAVQNMDLMLSA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_YERPP
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPQLASTLADRNISAAVSIDVRNMPESPEVFEHAMTQLPDSFSPQLLFLDADRNTLIRRYSDTRRLHPLSAKNLSLESAIDEESDLLEPLRSRADLIIDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVISFLDRHTEVHNFIYQTRSYLEQWLPMLETNNRSYLTVAIGCTGGKHRSVYVAEQLADYFRARGKNVQSRHRTLEKRKQ
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: IMQH_ASPFN
Sequence: MPAPKSIIIVGSGVFGLSTAHAMSQNNEFASSKITLIDSWNFEPSGPSASAPNPSAANFDTSRIIRSDYSHRTYATLAREAQQKWKADWGADGRYRNQSIVMIGEGHSMKQPMKALESINYVKHAYAQSYERAGRNSDIVHILDSESAVWEALGLGTPDEASKAGPNASELRGYRNHNCGWAESGATMAWLRQKTIHSDRIDIHIGQVVGLRVCSDSPSESHVNAEPRVCGVILDDGSQLTADLTVLAAGAMTPRLLGSPTLCDVYSETVAYVQLTEMERRELVRREFPLIVNVARKIFAIGPDNQGFLKLARFSWSGYRDVQKFAGVDVGPRSQAAPQEEDGYGACGDLDQTKLSPDVESTLQDYRGFLRELFRSGDGGDLGGLRNIATRPFAQVRRCWYADTVSTDFIVDYHPAYGKSLFIATGGSDHAFKFLPVLGERICELILQSDNGKAGPSESIQELQRLWKFPGGDSHAKL
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of imizoquins A to D, tripeptide-derived alkaloids that serve a protective role against oxidative stress that are essential for normal germination (PubMed:29182847).  ImqB is a canonical three-module NRPS that assembles the tripeptide backbone of the imizoquins via condensation of Trp, Tyr, and Leu-derived precursors (PubMed:29182847).  N-methylation by imqF and phenol oxidation by imqC, followed by cyclization via the FAD-dependent oxidase imqH carry out the three-step transformation of L-tyrosine into tetrahydroisoquinoline (PubMed:29182847).  Importantly, this sequence requires the presence of a free amine in the tyrosine moiety, indicating that isoquinoline formation occurs prior to peptide bond formation (PubMed:29182847).  The imidazolidin-4-one ring of imizoquins could form following additional oxidation of the methyl-derived bridgehead carbon by imqH (PubMed:29182847).  Lastly, O-methylation by imqG and leucine hydroxylation by imqE complete biosynthesis of the imizoquins (PubMed:29182847).
What are the official names of this protein?
Amino acid oxidase imqH, Imizoquin biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family.
Protein: PNO1_DANRE
Sequence: MESVSDSTAEVSATMDCDGNTEAFEKVKSKKREKCKRAAAEMDTQTEESSSSAPVKRPHFPALSGDQLGGGVDEMRKVPVPSHRYTPLKENWLKIFTPIVENLQLQVRFNLKTRQVEIKTCKETQDIGALTRAADFVKAFVLGFQVEDALALIRLDELFLETFDVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTKTRIVLADTKIHILGSFQNIKMARTAICNLILGSPPSKVYGNLRAVATRSAERF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.