PharMolix/UniProtQA huggingface dataset:
Protein: CH605_PARXL
Sequence: MAAKEIIFSDVARSKLVEGVNILANAVKVTLGPKGRNVVLERSFGSPVVTKDGVSVAKEIELPDRVQNIGAQLVKEVASRTSDAAGDGTTTATVLAQAIVREGQKYVAAGLNPLDLKRGIDKAVVAAIDELKKISKPTTTSKEIAQVATISANGEESIGQRIAEAIDRVGKEGVITVEDGKSLDDELDVVEGLQFDRGYLSPYFINDQDKQVAVLDNPYVLLHDKKVSNIRDLLPVLEQVAKASRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKALLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVGKENTTVIDGAGEHKNIEARVKQIRAQIDEASSDYDREKLQERVAKLAGGVAVIKVGGATEIEVKEKKDRVDDALHATRAAVEEGIVPGGGVALIRVRNAISGLKGANADQDAGIKIVLRALEEPLRQIVTNAGEEASVVVAKVAEGSGNFGYNAQTGEYGDLVESGVLDPTKVTRTALQNAASVAALLLTTDATVYEAPKDPAPATSAAGPGAPGAGYDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 5, 60 kDa chaperonin 5, Chaperonin-60 5, Cpn60 5.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUO9_BLACR
Sequence: AVVPASTVKTALAYTYPIHPYHSVYAHPHSVVIY
What are the official names of this protein?
Cuticle protein 9, BcNCP3.8.
Protein: REX_CLOK5
Sequence: MDKKKDISMSVIKRLPKYHRYLGNLMRNDVDRISSKELSEKIGFTASQIRQDLNCFGDFGQQGYGYNVSELYSQMCNILGLTKVYRTVIIGAGNIGQAISNYIGFEKLGFELRAIFDINPKLIGISIRDIEIRDIDYLGDYLRENVIDIGIICVPSNNGQKVCNILVKNGVKGIWNFAPVDLIVPEDVKVENVHLSDSLLTLSCLLNDIE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F229B_HUMAN
Sequence: MPFQFGTQPRRFPVEGGDSSIELEPGLSSSAACNGKEMSPTRQLRRCPGSHCLTITDVPVTVYATTRKPPAQSSKEMHPK
What are the official names of this protein?
Protein FAM229B.
What is the protein family that this protein belongs to?
Belongs to the FAM229 family.
Protein: YOSQ_BACSU
Sequence: MIRKEVEEAPWWITETGVIISKKLKKPRKTFITPHGYEMIGYTHPKKGTQNYLVHRLVAKYFIYDIPKGMFVNHIDGNKLNNHVRNLEIVTPKENTLHAMKIGLMSGQPGESNSMSKLTNMEATNLIYDLIAGMNNVEAGEKYSLHPRYVSLIRHKRRWKTLWDRIERSTTIA
What is the function of this protein?
A possible homing endonuclease, it is entirely encoded within the YosP intron.
What are the official names of this protein?
SPbeta prophage-derived putative HNH homing endonuclease YosQ.
Protein: KCNKC_HUMAN
Sequence: MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR
What is the function of this protein?
Probable potassium channel subunit.  No channel activity observed in heterologous systems.  May need to associate with another protein to form a functional channel (By similarity).
What are the official names of this protein?
Potassium channel subfamily K member 12, Tandem pore domain halothane-inhibited potassium channel 2, THIK-2.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLD_CORUL
Sequence: MKKKVVLFLSIIMGILFPVGNAVATPVSHDAASTGNRPVYAIAHRVLTTQGVDDAVAIGANALEIDFTAWRGGWWADHDGIPTSAGATAEAIFKHIAEKRNQGANITFTWLDIKNPDYCTDPHSVCSINALRDLARKYLEPAGVRVLYGFYKTVGGPGWKTITSDLRDNEAVALSGPTRDVLNDFAKAGDKILTKQKIADYGYYDINQGFGDCYGDGNKTCDQLRKSSEARDQGKLGKTFGWTITTGQDDRVNDLLGKAHVDGMIFGFKVTHFYRHADTENSFKAIKTWVDKHSDTHHLATAADNPW
What is the function of this protein?
Virulence factor affecting bacterial dissemination and survival within the host.  Has magnesium-dependent catalytic activity toward sphingomyelin (SM) and acyl- and alkyl-lysophosphatidylcholine (LPC), but not toward sphingosylphosphorylcholine (SPC) and phosphatidylcholine (PC).  Lysophosphatidic acid (LPA), assumed to result from LPC hydrolysis, evokes pathophysiological responses after LPA receptor internalization.  Shows hemolytic activity.
What are the official names of this protein?
Phospholipase D, PLD, Choline phosphatase, Sphingomyelinase D, SMaseD.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelinase D/phospholipase D family.
Protein: RSMH_CUPMC
Sequence: MSPTESPGTTTLRHRTVLLDEAVDALVWRPDGAYVDGTFGRGGHSRAVLARLGPAGTLVAFDKDPAAIAEAGTIKDARFSIEHASFAEMGDRLAGRGPVAGVLLDLGISSPQIDEAARGFSFRFEGPLDMRMDTTRGITAAEWLAQADEQDIARVIRDYGEERFALQIAKAIVARRRESGDGGALATTSDLAALVAKAVKTREKGQDPATRTFQALRIYINQELEDLERGLKAAYELLQVGGRLVVISFHSLEDRIVKRFMQAHARPERDADPALRRAPLRAADLPQPTMKLLGRFKPGAEEVAGNPRARSAVMRVAEKLGEQSA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_BACC0
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT5_YARLI
Sequence: MSDREESGSPEPRSKIEEDLESDEEVKTIKSEEVDKTQDNVEDEDDEEEEEEEEEEEEEDDDEEDVRQRKKPRRERRNQFLDVEAEVDEDEEDLEEDEDGLIGEDGFVAEPDADEPDASDDRFHREMDRRREAIAEEDAERLADEYREKYGRSTANKYRGDSGVIPQHLLLPSVNEPSIWGIRCKPGKEKELVRQCLRKKLSLQKSRNPLEIMSVFQRDTFTGYIYMEARNQQAVTVALKGLVNVYPQNMILVPIKEYVDLLRATKSAETELVPGAYVRLKRGKYGGDLAIVENLSENGLEVRLKLVPRLDYGRNAEAGIDGKRKRVARIPPPRLFSEQEASQYDPRNLQKRGPNAYVYAGDEYIGGFLYKDFKITLVNAENVAPKLEELTRFNSEETDGIDLASLAQSLRKSAAAVQFQGGDVVEVSEGEQTGVQGTVISTHGDIVTVEATTAPLVGKRIDLPSRSLRKKFAIGDHVRVISGNFLDDTGLIVGLEDDSVTLLSDLNKKEVTVFAKDLKKVSDIGGSHQVGDYELHDFVQLDALHVGCIVKVERDSLKVLDQEGTVRSVTPSSITMKLTRNMEGLATDSNGSEIKIGDTVRETVGEGRQGAVLHIYKNTLFLSSRSLGVFVAKAFKVNTIVAKGARTQSNSQATGPDLTKMNPAVYNARPGQMAPPVMPKQGGFDRLKGKHVAIGPGSQHKGCKGIVKETTDDIARVELHAPCKVVNVLKHQLRIYDDYKKTYLSYMEFATPRGMRSGGGRPGGPPGPGGPGSGGQTPSWGGGGKTPSWGAGGKTPSWGSKTPSWGGAKTSSWGSRTPAANAGGAQTPAWGAMGNKTPSWGASESRTPAWGGAKTPAWGAAGAGSKTPAFGVARTPSWKSSSAGTYGGSSSRNKGWEDLGSGNSAPTPGYAAATPGEMMGAPTPGAAHHPWEDSAPTPAAYNDARTPGVYDPRGSGPAQAETPAAWSTDDAPRYDDSPTP
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT5, Chromatin elongation factor SPT5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y987_METTH
Sequence: MHPQAVRPSETLKAFGDKLSMIGVTRITEITHLDRIGIPVFSAIRPTAEDGAVSIYAGKGATRTQARASAMMEAFERYSAERKPEDETFTAHPEDCDGLDPESLILPGSTDLKSELEWINAENLTGDEEVPVPANAVFHPYNPPEGCMSLFRSNTNGLASGNAREEAIFHGLMEVIERDAWSLFEARRGPKVEVDCSGTDNDIISGLLEKFHAAGVEVTLVDLTADTGVATVAAVADDTVLRDPALLTMGVGTHLDPEIAVIRALTEVAQSRATQIHGTREDTVRAEFMRRAGYERMKRLNRHWFSEPEDTITLDEMEDLSTRSFRGDLEITLRKLRESGLEDVFYVDLTRDVGVPVVRVIVPGLEVFSVDPERVGRRIRSSI
What are the official names of this protein?
Uncharacterized protein MTH_987.
Protein: RIHB_ECO8A
Sequence: MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRKQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: SYY_RUEPO
Sequence: MTYHPKSDFIAVMMERGFLADCTDYQGLDEALMKGCQPGYIGFDATAKSLHVGSLIQIMMLRWLQKTGHKPITLMGGGTTKVGDPSFRADERPLLTPAQIDDNIAGIRKVFAAYIDYDSGAENAALMLNNEEWLDDLNYLDFLRDIGRHFSVNRMLSFESVKSRLDREQSLSFLEFNYMILQAYDFMELNRRYGCILQMGGSDQWGNIVNGIDLTRRVIDHEVYGLTSPLLTTSDGKKMGKSQDGAVWLNPDMRSPYEFWQFWRNTTDADVGRFLKLYTELPVGECDRLGALAGSEINAAKVILANEVTALCHGAEAAATAEATAREVFEKGGIGDDLPTLTLGAADLPASIVQLIVKTGLAKSGKEAKRLIAEDGARLNDAPLTDAGMMIEAGDLAAPIKLSAGKKRHALVQLG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TWS1B_DANRE
Sequence: MGSSSSSSVVLLLLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQDKQCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY
What is the function of this protein?
Involved in dorsal-ventral patterning.  Appears to function predominantly as a ventralizing factor, through its actions as a BMP signaling agonist, acting through both chd-dependent and chd-independent mechanisms.  May also antagonize BMP signaling, probably via formation of ternary complexes with chd and BMPs, resulting in dorsalization.
What are the official names of this protein?
Twisted gastrulation protein homolog 1-B.
What is the protein family that this protein belongs to?
Belongs to the twisted gastrulation protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSPO2_MOUSE
Sequence: MQLQGPVFVGVPLLGPILICMLIHQPSSRCEDERKLPWCPPHKVILLVWVTIYSVMGYASYLVWKELGGGFRWPLALPLGLYSFQLALSWTFLVLFLAADSPGLALLDLLLLYGLVASLVFIWQPINKLAALLLLPYLAWLTVTTAITYRLWRDSLCPTYQP
What is the function of this protein?
Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum (PubMed:19729679, PubMed:32358067).  Required to meet cholesterol demands during erythropoietic differentiation (PubMed:19729679, PubMed:32358067).  May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid (By similarity).
What are the official names of this protein?
Translocator protein 2, Peripheral-type benzodiazepine receptor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
Protein: HBA_BRATR
Sequence: VLSAADKAHVKAFWTKIGGHAGEYGGEALERTFLSFPTTKTYFPHFDLSPGSAQVKAHGKKVGDALTLAVGHLDDLPGALSDLSDLHAHKLRVDPVNFKLLGHCVLVTLALHHPDAFTPAVHASLDKFITTVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MUTL_PARD8
Sequence: MSDIIHLLPDHIANQIAAGEVIQRPASVVKELVENAVDAGASNIQVNIKDAGKTLIQVIDDGKGMSETDARMAFERHATSKISTAEDLFSLHTMGFRGEALASIAAVAHIELRTRARGTELGTCLSIAGSNLESIEPEACNEGSIFSVKNLFFNVPARRKFLKSNETEFRNIINEFERIALVNPQVGMSLYHNDAEIFNLPESGLRQRIINIYGKSLNQKLLSLDAQSSMVTISGFVGRPDSAKKRGALQFFFVNGRYMKHPYFHKAIMQAYEQLIPAGDMPNYFVYFTLDPSSIDVNIHPTKTEIKFENEQPIWQILMAATREALAKSSAIPTIDFDVEDAIDIPVYNPVKKSEPSTYKAPKVQVDSSYNPFDTTSYKKPEFDWSKLYQGFENDRVAVQRESETFEDAPIEELPAEASDPEKLFTEVSNPCYQYKGRYIVTSLKSGLAIIDQHRAHVRILFDQYLSNIRQQQGVSQQVLFPEIVEFTAAEAAVLPSLLEDLCFVGFDLSNLGNDNYAINGLPAGIENLDPVNLVKDIVDRAIETGCAVHEKICEAIALSLAKAAAIRPGKSLSLEEMDHLIASLFSCSDSNLTPDGKTIISMLTDEELERRFKC
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GCS2_BRADU
Sequence: MLRLDSSDDKQHLVIRSAGGRGKAAEYSFGIEEEYFLADRRSLDVAIQTPNELFESANWSTGGQAMREMLQSQLEVATNVHVDVNDAREELRFLRREVANVAAQYGFVIMACGTHPTAVWRMSQPSPKPRYEEMIEDLRSIGHRNMMCGMHVHVQLPDPEKRMAVMRAMLPHLPLFIALSASSPFWNSHKTGLKGYRLAAYSELPRTGLPELFESRHDYDEYVGALQRSGVIPDESHIWWAMRPSMKHPTLELRAPDTCTFVDDAVAIASLYRCLTRHLYRRPHLSKTVTVVERAIAVENKWRAQRYGTDCIFASKDGPITISELLSRLIDDIVEDADALNCAAEVEHCRTIVERGSSAEFQLRAYRENGNDIAAVSRWIAASTISGRALRSDAPRLRRHSARASFGNDNGIPEFAVSRAVSWRKA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: NRIP3_HUMAN
Sequence: MFYSGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNILQRRLMETNLSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVKALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRLDCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFVETVSLNEDNTSEA
What are the official names of this protein?
Nuclear receptor-interacting protein 3, Sarcoma antigen NY-SAR-105.
Protein: STS1_YARLI
Sequence: MMGSVVPLSSPAWDLNLSAGQNLLGHGSPTPSHSRKRRLSVTPEAGDSHMEHESPSKPRQQSPFVHKRARVTRQLQSRPLPMSRLLSSLDQKTLVSLLEGICAQDDRVARQVMEVTPKPTVSSAMDVLSRALDQAFALFPYKGDHQNDYAFFRVRPALEEFLAELSDYLSHFLPPNETQVSNSFAFLDQATSLVHRMPQWSSPANNRLKEETYEHIDVAWTLVCEEAAKRQRGSLAMSGVGNWLIRLEKHNELSGDRLKTSLHLLRDMLDDQGYRPPNPFASFNGAQQLFTV
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL5_COREF
Sequence: MAENYTPRLKSRYQDEIRPNLQTQFEFSNVMQIPGVTKVVVNMGVGDAARDSKMINGALEDLTAITGQKPQLRRAKKSIANFKLREGMPIGAKVTLRGDRMWEFLDRLLTVALPRIRDFRGLSDQQFDGHGNYTFGLTEQTMFYEIDVDKIDRPRGMDITVVTTAVTDDEGRALLRELGFPFKGEDGKKQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL6_PYRAB
Sequence: MPVDAWVREEIEIPEGVEVSVQGNTVKVKGPKGEVERELFWPGVKIFVEGGKVVIYKDFPRRKDVAIVRTFKAHINNMIKGVTEGFTYKLKVVYSHFPITVKVQGDEVIIENFLGEKAPRRAKILPGVTVKVKGQEIIVEGIDKEAVGQTAANIEQATRITKWDRRVFQDGIYIVEKAGKPITF
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YQ58_CAEEL
Sequence: MVFFSCNNCGEACKKNQVERHLFQCRNTTFSCIDCQLVYTRETYKDHVKCITENQKYGGKNYVEKENKGEAKQNAWVDQVNRAIEFVTDSQVKELLKSVAGFANIPRKEAKFINFLTNSCRLRDKNLALRAWQAIAAEADKMREEAIRKQEETQKMEKAQKEAAAAAKKETTVATTAAEVTDAPESTFKWKKVIKRKLKENGGEMKIKKLKKAIIEELSAAGAASDDVDSIFDEKLQKCAAVTVDGKKVSLVV
What are the official names of this protein?
Uncharacterized protein C16C10.8.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDL_NEIMA
Sequence: MQNFGKVAVLMGGFSSEREISLDSGTAILNALKSKGIDAYAFDPKETPLSELKAQGFQTAFNILHGTYGEDGAVQGALELLGIPYTGSGVAASAIGMDKYRCKLIWQALGLPVPEFAVLHDDTDFDAVEEKLGLPMFVKPAAEGSSVGVVKVKGKGRLKSVYEELKHFQGEIIAERFIGGGEYSCPVLNGKGLPGIHIIPATEFYDYEAKYNRNDTIYQCPSEDLTEAEESLMRELAVRGAQAIGAEGCVRVDFLKDTDGKLYLLEINTLPGMTGHSLVPKSAAVMGVGFADLCIEILKTAHVG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_CITBB
Sequence: MKNSSIVLASASPRRSELLESAGIQFRVVPADINEEPFPGEEPVDHVQRLAEGKARAAAELAEGRFFLGADTIVLCDGEIMGKPKDAADAKRMLNKLSGVPHEVVTGFAIYDRERKGAVVEAIRTKVFFKKLRDEEILDYIATGCPFDKAGAYAIQGGAAHMVQKIEGSYTNVVGLPLCEVVDALRVIGALGN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_BORHD
Sequence: MLGLIGKKVGMTQVFQGNGVVVPVTVIEFEPNYIIGKKTVERDGYDALIMGSVDLKSSKISKPIKGQYKNLENVEPKKYVIEFKGLKGYDAGDEVGLDAFKEIKYVDITGTTKGKGFQGAMKRHNFSGGPSSHGSKFHRHLGSTGQAATPSRTFKGTKMAGRMGGEQQTIQNLEVVFIDEEKRAILVKGAVPGVKGSFVIVKKAKKVGV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CASK_BOVIN
Sequence: MMKSFFLVVTILALTLPFLGAQEQNQEQPIRCEKDERFFSDKIAKYIPIQYVLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLSNTVPAKSCQAQPTTMARHPHPHLSFMAIPPKKNQDKTEIPTINTIASGEPTSTPTTEAVESTVATLEDSPEVIESPPEINTVQVTSTAV
What is the function of this protein?
Casoplatelin inhibits platelet aggregation.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_SHEVD
Sequence: MSKSKEKYSQLRSFIPEMRRVKHIYFVGIGGAGMGGIAEVLVNEGYRLSGSDIAENAVTERLKSLGVQIHIGHHADQVHGTDVVVVSTAIDAENPELVAAKELRIPVVQRAEMLAELMRYRHGVAVAGTHGKTTTTSLIASIYAQADRDPTFVIGGLLNSAGTNARLGNSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYGGDFEKLKSTFIDFLHNLPFYGVAVMCIDDPVVRELLPKVGRKIVTYGFSEDADIQALNFVQQGYSSHFTLRRDGVEDIAVMVNLPGEHNVLNALASIAVATEDEIEDEAIVLALAQFEGIGRRFQQLGTFATSKGEVMLVDDYGHHPSEVAATIKAARLGWPDKRLVMIYQPHRYSRTRDLYDDFVEVLSQVDCLILLDVYSAGEAPVPGADSRALCRSIRQRGQLDPIFVAGTEQLLSLLPDVLQDGDLLLTQGAGNIGTLSKLIAQTNLGFEVVS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_NEOSM
Sequence: MDVVTRFAPSPTGNLHIGGLRTAIFNFLYARRHGGKFLLRIEDTDLARSNTAYLESILQALKWLSLSYDELVYQSVNVNRHREVALELLNRGKAYHDNGAVRLKVNHDETVKFSDLILGEISADGDSINDVVILRSDGSPTYMLAVVVDDHDMGITHIIRGSDHITNTFAQKLIYEGMGWSLPDFAHIPLIHNTHGAKLSKRDGAVDVIDYRTAGILPEAMFNYLLRLGWSHGDKEIFSIQEAIDLFDITAVGKSPARFDREKLYSLNSYYISGLPLERIASEVRSLVEEKIIVSYSAFIAFVELFRKKCSSIVELKDNLQFCWCTDSCLEVDRLLLQEVLKLLENTDWGPSLQQILKEYISLSGFSAKEVYTNLRMALIGQEHSPSVVEIMQIFGKDVVLKKLRNSLK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUMO2_MOUSE
Sequence: MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY
What is the function of this protein?
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer.  Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.  This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.  Plays a role in the regulation of sumoylation status of SETX (By similarity).
What are the official names of this protein?
Small ubiquitin-related modifier 2, SUMO-2, SMT3 homolog 2, Ubiquitin-like protein SMT3B, Smt3B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.