PharMolix/UniProtQA huggingface dataset:
Protein: SPK1_ARATH
Sequence: MENNNLGLRFRKLPRQPLALPKLDPLLDENLEQWPHLNQLVQCYGTEWVKDVNKYGHYENIRPDSFQTQIFEGPDTDTETEIRLASARSATIEEDVASISGRPFSDPGSSKHFGQPPLPAYEPAFDWENERAMIFGQRTPESPAASYSSGLKISVRVLSLAFQSGLVEPFFGSIALYNQERKEKLSEDFYFQIQPTEMQDAKLSSENRGVFYLDAPSASVCLLIQLEKTATEEGGVTSSVYSRKEPVHLTEREKQKLQVWSRIMPYRESFAWAVVPLFDNNLTTNTGESASPSSPLAPSMTASSSHDGVYEPIAKITSDGKQGYSGGSSVVVEISNLNKVKESYSEESIQDPKRKVHKPVKGVLRLEIEKHRNGHGDFEDLSENGSIINDSLDPTDRLSDLTLMKCPSSSSGGPRNGCSKWNSEDAKDVSRNLTSSCGTPDLNCYHAFDFCSTTRNEPFLHLFHCLYVYPVAVTLSRKRNPFIRVELRKDDTDIRKQPLEAIYPREPGVSLQKWVHTQVAVGARAASYHDEIKVSLPATWTPSHHLLFTFFHVDLQTKLEAPRPVVVGYASLPLSTYIHSRSDISLPVMRELVPHYLQESTKERLDYLEDGKNIFKLRLRLCSSLYPTNERVRDFCLEYDRHTLQTRPPWGSELLQAINSLKHVDSTALLQFLYPILNMLLHLIGNGGETLQVAAFRAMVDILTRVQQVSFDDADRNRFLVTYVDYSFDDFGGNQPPVYPGLATVWGSLARSKAKGYRVGPVYDDVLSMAWFFLELIVKSMALEQARLYDHNLPTGEDVPPMQLKESVFRCIMQLFDCLLTEVHERCKKGLSLAKRLNSSLAFFCYDLLYIIEPCQVYELVSLYMDKFSGVCQSVLHECKLTFLQIISDHDLFVEMPGRDPSDRNYLSSILIQELFLSLDHDELPLRAKGARILVILLCKHEFDARYQKAEDKLYIAQLYFPFVGQILDEMPVFYNLNATEKREVLIGVLQIVRNLDDTSLVKAWQQSIARTRLYFKLMEECLILFEHKKAADSILGGNNSRGPVSEGAGSPKYSERLSPAINNYLSEASRQEVRLEGTPDNGYLWQRVNSQLASPSQPYSLREALAQAQSSRIGASAQALRESLHPILRQKLELWEENVSATVSLQVLEITENFSSMAASHNIATDYGKLDCITTILTSFFSRNQSLAFWKAFFPIFNRIFDLHGATLMARENDRFLKQIAFHLLRLAVYRNDSVRKRAVIGLQILVKSSLYFMQTARLRALLTITLSELMSDVQVTHMKSDNTLEESGEARRLQQSLSEMADEAKSVNLLRECGLPDDTLLIIPEKFTENRWSWAEVKHLSDSLVLALDASLGHALLGSVMAMDRYAAAESFYKLGMAFAPVPDLHIMWLLHLCDAHQEMQSWAEAAQCAVAVAGVIMQALVARNDGVWSKDHVSALRKICPMVSGEFTTEASAAEVEGYGASKLTVDSAVKYLQLANKLFSQAELYHFCASILELVIPVYKSRKAYGQLAKCHTLLTNIYESILDQESNPIPFIDATYYRVGFYGEKFGKLDRKEYVYREPRDVRLGDIMEKLSHIYESRMDSNHILHIIPDSRQVKAEDLQAGVCYLQITAVDAVMEDEDLGSRRERIFSLSTGSVRARVFDRFLFDTPFTKNGKTQGGLEDQWKRRTVLQTEGSFPALVNRLLVTKSESLEFSPVENAIGMIETRTTALRNELEEPRSSDGDHLPRLQSLQRILQGSVAVQVNSGVLSVCTAFLSGEPATRLRSQELQQLIAALLEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTAELSHYIPAILSEL
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for Rho and Rac.  GEF proteins activate small GTPases by exchanging bound GDP for free GTP.  Controls actin polymerization via the two heteromeric complexes WAVE and actin-related protein (ARP) 2/3 (PubMed:18308939).  Involved in cytoskeletal reorganization required for cell shape (e. g.  trichome and cotyledon) control and tissue development (PubMed:11826302).  Promotes polarized growth and cell-cell adhesion in the leaf epidermis probably by promoting the formation of endoplasmic reticulum (ER) exit site (ERES) and/or trafficking between the ER and Golgi (PubMed:21109438).  Triggers ARAC3/ROP6 activation required for auxin-mediated inhibition of PIN2 internalization during gravitropic responses (, PubMed:22683260).
What are the official names of this protein?
Guanine nucleotide exchange factor SPIKE 1.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Note=Accumulates at, and promotes the formation of, a specialized domain of the endoplasmic reticulum termed the ER exit site (ERES).
Protein: ODP2_AZOVI
Sequence: MSEIIRVPDIGGDGEVIELLVKTGDLIEVEQGLVVLESAKASMEVPSPKAGVVKSVSVKLGDKLKEGDAIIELEPAAGAAAAPAEAAAVPAAPTQAVDEAEAPSPGASATPAPAAASQEVRVPDIGSAGKARVIEVLVKAGDQVQAEQSLIVLESDKASMEIPSPASGVVESVAIQLNAEVGTGDLILTLRTTGAQAQPTAPAAAAAASPAPAPLAPAAAGPQEVKVPDIGSAGKARVIEVLVKAGDQVQAEQSLIVLESDKASMEIPSPAAGVVESVAVQLNAEVGTGDQILTLRVAGAAPSGPRARGSPGQAAAAPGAAPAPAPVGAPSRNGAKVHAGPAVRQLAREFGVELAAINSTGPRGRILKEDVQAYVKAMMQKAKEAPAAGAASGAGIPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAEKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: RNPA_STRPJ
Sequence: MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGLSVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLHVLKLSKIYREGNGSEKETKVD
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CLPP_LISMF
Sequence: MNLIPTVIEQTSRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLDAQDPEKDIFLYINSPGGSISAGMAIYDTMNFVKADVQTIGMGMAASMGSFLLTAGANGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILKIKERMNTIMAEKTGQPYEVIARDTDRDNFMTAQEAKDYGLIDDIIINKSGLKG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D131B_HUMAN
Sequence: MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLKIIQIDGQKKW
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 131B, Defensin, beta 131.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCIU_ECOHS
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: RS14_METPP
Sequence: MAKLSIKQRELKREQLVAKFAKKYAELKAIINDAGKSDEERYTARLALQKLPRNAYPSRLRNRCELTGRPRGTFRTFGLARNKIRELAFKGDIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DMC1A_ORYSI
Sequence: MAPSKQYSEGGQLQLMDAERIEEEEECFESIDKLISQGINSGDVKKLQDAGIYTCNGLMMHTKKSLTGIKGLSEAKVDKICEAAEKLLSQGFITGSDLLIKRKSVVRITTGSQALDKLLGGGIETLCITEAFGEFRSGKTQLAHTLCVSTQLPIHMHGGNGKVAYIDTEGTFRPERIVPIAERFGMDANAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFSGRGELAERQQKLAQMLSRLTKIAEEFNVAVYITNQVIADPGGGMFITDLKKPAGGHVLAHAATIRLMLRKGKGEQRVCKIFDAPNLPEGEAVFQVTSGGIMDAKD
What is the function of this protein?
Recombinase that may participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (Probable).  Exhibits DNA-dependent ATPase activity when bound to single-stranded DNA (ssDNA).  Mediates renaturation of homologous complementary strands as well as assimilation of single strands into homologous supercoiled duplexes leading to D-loop formation (PubMed:15821864).  Binds circular single-stranded DNA (ssDNA) and circular double-stranded DNA (dsDNA) in vitro (PubMed:15821864, PubMed:26118128).  Catalyzes DNA homologous renaturation and DNA strand exchange.  The rates of these activities are dependent on the state of ATP hydrolysis (PubMed:16689935, PubMed:26118128).  Forms helical filaments along ssDNA and dsDNA, and promotes strand exchange between ssDNA and dsDNA with long DNA substrates of several thousand base pairs.  The presence of the replication protein A is not required for this activity (By similarity).  Seems to be required for homologous pairing and subsequent chromosome segregation during male meiosis (PubMed:17562186).  May be not directly required for homologous pairing during male meiosis.  Required for synaptonemal complex assembly and crossover formation.  Functions redundantly with DMC1B (By similarity).
What are the official names of this protein?
Meiotic recombination protein DMC1 homolog A, OsDMC1A, OsDMC1, RiLIM15A.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP_VIBCM
Sequence: MSYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFRKEVVSLLSAFFASIFKGDRSKEAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATTTIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAIIPGTSRSGATITAALYLGFTREAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKLISRMGMTPFVIYRLVLGVGLFAFLLTQ
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURE_MYCTO
Sequence: MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQRLAGKLTRD
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: SCTC_YERPE
Sequence: MAFPLHSFFKRVLTGTLLLLSNYSWAQELDWLPIPYVYVAKGESLRDLLIDFSANYDATVVVSDKINDKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKLALQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQAKVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLIDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHHETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIDGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYLGALFRRKSELTRRTVRLFIIEPRIIDEGIAHHLALGNGRDLRTGILAVDEISNQSTTLNKLLGGFQCQPLNKAQEVQKWLSQNNKSSYLTQCKMDKSLGWRVVEGACTPAESWCVSAPKRGVL
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells.  Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
What are the official names of this protein?
Type 3 secretion system secretin, T3SS secretin, Type III secretion protein YscC.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. T3SS SctC subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: COPA2_ORYSJ
Sequence: MLTKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHHECPWIVSASDDQTIRIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDISALRKKSVSPADDILRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQTFRREHDRFWILSAHPEMNLLAAGHDSGMIVFKLERERPAFSVSGDTVFYVKDRFLRFFEFTTQKEVQLAPIRRPGSVSLNQSPKTLSYSPTENAVLICSDVDGGSYELYIVPKDSAGRADYLQDAKKGAGGSAVFVARNRFAVLEKSSNQVLVRNLKNEIVKKSPLPIATDAIYYAGTGSLLCKAEDRVTIFDLQQRLILGELQAPSVKYVVWSSDMESVALLSKHAVVIANKKLVHRCTLHETIRVKSGAWDENGVFIYTTLNHIKYCLPNGDSGIIKTLDVPIYITRVIGNNIFCLDRDGKNKLVTVDASEYIFKLALLRKRYDHVMSMIKNSQLCGQAVISYLQQKGFPEVALHFVKDEKTRFNLALESGNIQIAVASAKEIDDKDHWYRLGIEALRQGNVGIVEYAYQRTKNFERLAFLYLITGYMDKVGFMCKIAGQNNNLMGQFHNALYLGDAMKRVEILENAGQLPLAYITATTHGLTEIADRLAAELGENIPSLPEGKARSLLIPPAPLTASGDWPLLRVMRGIFEGGLDATGKAELEEDDEAAGADWGDEGLDIVDASEAMANGGDGFDAEEGEANEEDGEEGGWDLEDLELLPEAETPKNAGNARSAVFVAPPPGMPVSLIWTQKSSLAGEHAAAGNFDTAMRLLSRQLGIKNFAPLKPLFLDLHMGSHSYLHALATAPIIPVAVEKGWSESASPNVRGPPALVFTFPQMEDRLKAAYKATTDGKFPEALRQFLSILHTIPLIVVDSRREVDEVKELIEIVREYVLGLRMELKRKELRDDVNRQQELAAYFTNCKLQRVHMRLVLGSAMGLCYKQKNFATAEHFARMLLENNPNEAQARRARQVQQQCSGKKDSSELNYDYRNPFVVCGATYVPIYRGQKDVSCPYCGSRFVPSIEGQLCTICELAVVGADASGLVCSPTQLR
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit alpha-2, Alpha-coat protein 2, Alpha-COP 2.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: G6PI_PARMW
Sequence: MGKPGRSSIPSVGVHHQGPMSFPDFSASDAQIQWQRFCDLLWYHEDLGIWLDISRMHVNPSHLEQLQPGFDKAFAAMAELEAGAIANPDEQRQVGHYWLRTPQLAPNEAVRDQIATEIDQIDQFGRDVISGVIKAPGGQPFTDVLWIGIGGSGLGPLLMIRALQGHGSGLPFHFFDNVDPNGMSAVLAELDDRLATTLVVTVSKSGGTPEPHLGMEQARHRVESRGGRWADQAVAITMVDSKLDREAQQDGWLKSFSMFDWVGGRTSITSAVGLLPGALIGADIRDFLAGAAQMDDATRLADLRRNPAALMAASWFVAGDGKGRRDMVVLPYRDRLEVFSRYLQQLVMESLGKRLDRDGNEVNQGIAVYGNKGSTDQHAYVQQLRDGVDNFFATFIEVLEDVSDIPVIKDECPGDFLDGFLQGTRSALTEGGRQSLSISMRRFDARRLGALIALFERAVGFYGDLVNINAYHQPGVEAGKKAAAAILDLQSRVEAVLKDGAPRTVSEIRQAVGDGSDEAIFWIMRHLAGNDRGYRAEGDWANPASIRFSCS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2415_ARCFU
Sequence: MIGIVSYGSYVPKFRIRVEEIARVWGEDAKKIKDGLGVHEKSVPGMDEDAATIAVEAAREAIRRAGINPEEIGAVFVGSESHPYAVKPTATIVGEALGVGNDYFAADLEFACKAGTAGMQICYSMVKAGMIKYGLAIGADTSQARPGDALEYAAAAGGAAFIIGENPIAEVEATYSFTSDTPDFWRRDLQPYPSHGGRFTGLPAYFRHVISAAKGLMEKYGYKVEDFDYAVFHMPNAKFPVRAAKMLGFSMEHISQGLVVKAIGNTYSGSSLLGLAATLDVAEPDERILLVSFGSGAGSDAFAIRVTDAIENYPREPKVWEKIERKAYVDYAIYLKHRRKIKA
What are the official names of this protein?
UPF0219 protein AF_2415.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: SIGNS_REOVD
Sequence: MASSLRAAISKIKRDDVGQQVCPNYVMLRSSVTTKVVRNVVEYQIRTGGFFSCLAMLRPLQYAKRERLLGQRNLERISTRDILQTRDLHSLCMPTPDAPMSNHQASTMRELICSYFKVDHADGLKYIPMDERYSPSSLARLFTMGMAGLHITTEPSYKRVPIMHLAADLDCMTLALPYMITLDGDTVVPVAPTLSAEQLLDDGLKGLACMDISYGCEVDANSRPAGDQSMDSSRCINELYCEETAEAICVLKTCLVLNCMQFKLEMDDLAHNAAELDKIQMMIPFSERVFRMASSFATIDAQCFRFCVMMKDKNLKIDMRETTRLWTRSASDDSVATSSLSISLDRGRWVAADASDARLLVFPIRV
What is the function of this protein?
Protein that binds to ssRNA and may be involved in genome packaging.
What are the official names of this protein?
Protein sigma-NS, SigmaNS.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus sigma-NS protein family.
Protein: GHRB_ECO57
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRC9_BOVIN
Sequence: MEEGLEASNLPPEAWPSEVTVSVTGEPPNTSVEEKEETAKEAVIETSPEIMKPLSILDVLRISAVLEDTTDQLSILNYIMPVQYEKRQSISMKDNKEMHLEGRSSEKVPLASNPSKISSPLVHKEEPKLPEIRQGGQFNKVQDLIFKKPTRQTIMNTETLKKIQIDRQFLSDVITETLEELQEEGTFTNLLKALGKERESKMHFYDTIAREENGRKKIKSLQKQLLNVKKERQAEVQNRNEYIAHLKDQLQEMKAKTNMENRYMKRNTELQISQTQKKCSKTEELLLEEIEKLRLKTEEENRIHAEIELFLRKEQQKLEEKLEFWMEKFDKDTEMKQNELNALKSAKASDLAHLQELAKTIREYEQVIIEDRIEKEKTRKKREQDDLEMRSIIKLQAWWRGTVVRREIGGFKMPKDKDDSKDVKGKGKEKDKRRGKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades.  Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
What are the official names of this protein?
Dynein regulatory complex protein 9, IQ domain-containing protein G.
What is the protein family that this protein belongs to?
Belongs to the DRC9 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum. Cell projection, cilium. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme. Note=First detected in the cytoplasm of pachytene spermatocytes. Colocalizes with alpha- tubulin at the manchette in developing spermatids. Detected in the flagellum of mature testicular spermatozoa, and in the flagellum and post-acrosomal region of the head of epididymal spermatozoa. Detected in cilia in trachea and oviduct.
Protein: SUT32_ARATH
Sequence: MSSKRASQYHQVEIPPPQPFLKSLKNTLNEILFADDPFRRIRNESKTSKKIELGLRHVFPILEWARGYSLEYLKSDVISGITIASLAIPQGISYAQLANLPPILGLYSSLVPPLVYAIMGSSRDLAVGTVAVASLLTAAMLGKEVNAVVNPKLYLHLAFTATFFAGLMQTCLGLLRLGFVVEILSHAAIVGFMGGAATVVCLQQLKGLLGLHHFTHSTDIVTVLRSIFSQSHMWRWESGVLGCCFLIFLLTTKYISKKRPKLFWISAMSPLVSVIFGTIFLYFLHDQFHGIQFIGELKKGINPPSITHLVFTPPYVMLALKVGIITGVIALAEGIAVGRSFAMYKNYNIDGNKEMIAFGMMNILGSFSSCYLTTGPFSRSAVNYNAGCKTALSNVVMAVAVAVTLLFLTPLFFYTPLVVLSSIIIAAMLGLVDYEAAIHLWKLDKFDFFVCLSAYLGVVFGTIEIGLILSVGISVMRLVLFVGRPKIYVMGNIQNSEIYRNIEHYPQAITRSSLLILHIDGPIYFANSTYLRDRIGRWIDEEEDKLRTSGDISLQYIVLDMSAVGNIDTSGISMLEELNKILGRRELKLVIANPGAEVMKKLSKSTFIESIGKERIYLTVAEAVAACDFMLHTAKPDSPVPEFNNV
What is the function of this protein?
H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation.
What are the official names of this protein?
Sulfate transporter 3.2, AST77.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARLY_PASMU
Sequence: MALWGGRFTQAADKRFKDFNDSLRFDYRLAEQDIEGSIGWSKALVSVGVLTVQEQQQLESALNTLLIEVRSNPQAILQDDAEDIHSWVESKLIDKVGNLGKKLHTGRSRNDQVALDIKMWCKQRVIELQSSLHALQCKLVETAENNQHAVMPGYTHLQRAQPITFAHWCMAYVEMLDRDYSRLTDAYQRMNSCPLGSGALAGTAYAIDREQLALDLGFDVATRNSLDSVSDRDHIVELLSTASLSMAHLSRFAEDMIIFNSGESNFVELSDRVTSGSSLMPQKKNPDACELIRGKAGRVMGALTGMLMTLKGLPLAYNKDMQEDKEGIFDALDTWQDCIDMAALVLDGIQVNVERTKEAALKGYSNATELADYLVAKGVPFRDSHHIVGETVVYAIQQHKALEALSVAEFKQFSDVVEEDVYQILSLQSCLDKRCAKGGVSPLRVAEAIAEAKARLS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_THESA
Sequence: MNKYFENVSKIKYEGPKSNNPYSFKFYNPEEVIDGKTMEEHLRFSIAYWHTFTADGTDQFGKATMQRPWNHYTDPMDIAKRRVEAAFEFFDKINAPFFCFHDRDIAPEGDTLRETNKNLDTIVAMIKDYLKTSKTKVLWGTANLFSNPRFVHGASTSCNADVFAYSAAQVKKALEITKELGRENYVFWGGREGYETLLNTDMELELDNFARFLHMAVDYAKEIGFEGQFLIEPKPKEPTKHQYDFDVANVLAFLRKYDLDKYFKVNIEANHATLAFHDFQHELRYARINGVLGSIDANTGDMLLGWDTDQFPTDIRMTTLAMYEVIKMGGFDKGGLNFDAKVRRASFEPEDLFLGHIAGMDAFAKGFKVAYKLVKDGVFDKFIEERYASYKEGIGADIVSGKADFKSLEKYALEHSQIVNKSGRQELLESILNQYLFAE
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCHS_LENBU
Sequence: MSEFDKKLNTLGVDRISVSPYKKWSRGYMEPGNIGNGYVSGLKVDAGVVDKTDDMVLDGIGSYDRAETKNAYIGQINMTTASSFSGVGGTVISYDILRNPEVDKAKPLFTEKQWD
What are the official names of this protein?
Histidine decarboxylase proenzyme, HDC, Pi chain.
Protein: RL27_COXBR
Sequence: MAHKKAGGSTRNGRDSNPKMLGVKRFGGERVLAGNIIVRQRGTHYRPGENMGMGRDHTLYALIEGKVKFTRKGPKKRNFVSIEPLEESQP
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RIMM_PSEA6
Sequence: MSHASDTLVMGKIGAPYGVKGWVKITSYTDELDGIFSYTPWLVGQEGNTKEIVVDQWRTHNKGLVAKLVGVETRDDAESIKNLDISIKAQQLPQLDGDEFYWRELVGMQVVTEQGYNLGVVKELFETGANDVMLIKANLKDAFGQKERMVPYLIDQVVKKVDREAKTIQVDWDPSF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_DEIRA
Sequence: MLAKRIVPCLDVQNGRVVKNVRFFEDHRDAGDPLVLAQAYEAQQADELVFYDITATHEGRSLMLDVAARVAEQVMMPLTVGGGVGALSDFRQLLLAGADKISVNSGAVKRPELIREASDHYGAQCVMLSIDAKRRPGGQGWTVHIGGGRVDTGLDLLAWARRGQELGAGELCLNVMDADGTRAGFDLEATRAVAREVDLPVIASGGAGKVQDFYDVLTAGEADAALAASVFHFGELTVPQVKTSLAAQGVPVRPEWRGATE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.