PharMolix/UniProtQA huggingface dataset:
Protein: NUOB2_BURPS
Sequence: MANHPLTLEKDGFIVTTLDAAMAAAQKNSLWYMTFGLACCAVEMMHAAGARYDMDRFGMIPRASPRQCDLMIVAGTLTNKMAPAMRRVYDQMAEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGLMQLQRKVAERSTHSRPKLFARP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSLU_NATTJ
Sequence: MIISTEELTPQEIVERLDKYIIGQNKAKRSMAIAIRNRYRRQKLEEELKEEVIPKNILMIGPTGVGKTEIARRLAKLIKAPFIKIEVTKFTEVGYVGRNVESMVKDLVAESIQLVEEEKHEEVSKQARKQAENRIIDLLLSEKKSSSKGEQETDLRTRRREIKEQLFKGLLEDEYVTVKLEKEPAQDDNLMGEQFEEMGVNFKELFGKILPKESEHKKMTVKEARKVLTRQEADKLINKDQVNQEAIERAENYGIIFLDEFDKIAASSGKQSGGQDVSREGVQRDILPIVEGSTVNTRYGRVKTDHIMFIGAGAFHDSKPADLIPELQGRFPIRVELDSLTKDDFYRILTEPSNALLEQYKALLRTEEVKVNFTEDAIEELANMCEYVNENTEDIGARRLHTILETLLEELSFYAPEMKGQEVEINSNYVKDQLQDIVTEKDSSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y183_NEIMB
Sequence: MHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPFFTRKRGDTEWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPDTIAARAGFQSGDKIQSVNGTPVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAAGTPEAGKIAKNQGYIGLMPFKITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPIASWQEWANLTRQSPGKKITLNYERAGQTHTADIRPDTVEQSDHTLIGRVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHSWTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSYLEFLALVSISLGVLNLLPVPVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAVAFFNDVTRLLG
What are the official names of this protein?
Putative zinc metalloprotease NMB0183.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS7_BORT9
Sequence: MSRKSKKIKKKVFKDSKYDSQVIAKFVNRMMYDGKKSISEAIVYNSIDLLAEKTEEVDKVAAFSKALDNVKPLVEVRSRRVGGATYQVPVEVREERREALAMKWIIAAARKASGKSMQEKLGNELVNSYNSTGVAFKKREDTHRMAEANRAFTHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: S2538_SHEEP
Sequence: MIQKSRPALLQHQDVGDRVETLMLQPVIKAFLCGSISGTCSTVLFQPLDLLKTRLQTLQPSAHGSRRVGMLALLLTVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGAGSRSVAGVCMSPITVIKTRYESGRYGYQSIYAALRSICHSEGFRGLFSGLTATLLRDAPFSGIYLMFYSQTKNVVLHSTDQLDAVLVPVVNFSCGIFAGILASLVTQPADVIKTHMQLSPVKFRWIGQSVTLIFKDYGLRGFFQGSVPRALRRTLVAAMAWTVYEEMMAKMGLKS
What is the function of this protein?
Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MMR_MYCTU
Sequence: MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH
What is the function of this protein?
Multidrug efflux pump.  Confers resistance to tetraphenylphosphonium (TPP), erythromycin, ethidium bromide, acriflavine, safranin O, pyronin Y and methyl viologen.
What are the official names of this protein?
Multidrug resistance protein Mmr.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KITH_DICDI
Sequence: MIVTQIAGKIQVIFGPMFSGKTTELIRRIKRFNFANKKCLLIKYSKDTRYNDNIDKSFLVTHDKQNYQAFPCSILEDVKEQAQNYDVIGIDEGQFFPDVVQFSEDLANQGKTVIIAALDGTFQRKPFQSVIDLVSKAEYITKLTAVCMVCYNEAAFSKRIVESDDIELIGGIDKYISVCRGCYNSDQNEGNSTKPSKTARHSHSQSAPSVAPLAVNINPDDHLNNDY
What are the official names of this protein?
Thymidine kinase 1, TK1, Calmodulin-binding protein ThyB.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: Y237_VIBVU
Sequence: MKKMMILSALALFSSSLFAANLTLQKEITPQIVNGEGVTLQEVHNGNRIELKPGHNQIAVTIGQIVFEDGKRRKFDSQPLLLEFVAKPEQALTLKYGKFRTIDDAKKFENNPTVHLTDAQGNPVAFTMVQLYKGGLQGFRDYEREVADYNAQKAQKADSAPLVNHDPKAMDLKTAFKEMTRQEQQAFMQWAMQNLK
What are the official names of this protein?
UPF0319 protein VV1_0237.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: RS16_XANOR
Sequence: MVKIRLTRGGAKKRPFYHIIVTDVRSARDGRNIERLGYYNPVAQGAEPRVVLDTARVDHWVGNGAQLTDKVRNLYREAKSQAAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TBCC_YEAST
Sequence: MDFTAKIKELERELSETSDYKTLQKKTISLRSELNTLSHSLTSYEKEHFSNDIENVLKSINAKLSESKGKKRLFSFKQKNSSSAVHKNVERTELANAPAYTTTLKKHYVLEKGDSAFENLEFCTVTSTTDYSGNSALSGSLCFRNITKCVINLQRIFFQTGSIFITDCTDSIIFLRSPSDKDFQIRLRDLKNCKILIEKLSPSIDCKQVVIIENCHKCIFNASTRDHLIIQDFSNPFQSEETEDNSAFAFEDFDICNKDTMQLFRAYL
What is the function of this protein?
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone C, Chromosome instability protein 2, Tubulin-folding cofactor C.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PANC_ACIC1
Sequence: MIATGHGGAERRTTAGDGTARPVVARTIGELRAARAALTGPVAFVPTMGALHDGHRSLLRIARHHGDHVVVSIFVNPLQFGPAEDFDRYPRTLDADLAMCAAEGVDLVFVPPAAEMYPSEPQVRVSAGPLGERFEGSVRPGHFDGVLTVVAKLFQLVQPDVAVFGRKDAQQLALVRRMVADLNLPVQIIAAPTFREPDGLAASSRNRYLTDADRAQARALPTALTTAAAVAAAGGPPSEMIEMARKVLADAAVTLDYVAVVDEATFDEIDDAEWSQRGEGLCIAAIRVGGTRLIDNMPMRKAD
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3GA_XENLA
Sequence: MPTGDYDSKPSWADQVEEEGIDAEPLSPQIRKPDPVSFVLDTPREVINGNIKTITEYKLNDDDKTVKIVRTFKIETVKASKVVAQRKNWKKFGNSEYDPPGPNVATTTVSDDVLMTFITNKEDLNNQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGDKEKAPGAEPEPAQAPVSKTGKYVPPSLRDGGSRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-A, eIF3g-A, Eukaryotic translation initiation factor 3 RNA-binding subunit A, eIF-3 RNA-binding subunit A, Eukaryotic translation initiation factor 3 subunit 4-A.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD1_PLAF7
Sequence: MSEEHSNDHIEDVVLCSQNCDETNSPKNEKDEKDFKNFSSESSDSYYKNKFRLKKNSIEIKKKSLLKSKLKNDDIQTIIKNDPILSKLNKTMTTDDEIFDLANKKENKTKFKLEKEKEKNEKKEKKEKKVTNDSTNNKNKNNSVPFLNENQENKNQHNHNNKIKYELNEQTYDINNISEEILKKENHHTNIEYNEKVQDQDNTLNINQKVNKIQLNSTKKQKQKEKTKKEIKLNEQNEIKKNNQNFNSSILNEIKKNKELSPLSLIKKHGRLINNIEEIYNSNCEQIQNVRDEFAELKNDLNKIMNLINIGQKAVASLK
What are the official names of this protein?
Coiled-coil domain-containing protein PF3D7_1144200.
Protein: Y518_MYCPN
Sequence: MAQTTINEQTLVNEQRLLAYDCFQNTNKVGLLSALEYLDFVNHLVKSNQIKYLLVPSASQTVYQHVFFDHFRFLSFDNNLLSGFGLAIRLHKEAETVFMLVEKTKQTETEIKKLLEAVKQFSGLKLVVLLVNSPFENKRTKLSYEIVKIIKKHGYQYKRYCRKNFEKKFFNTWNHQKRKQKTKNNLFFVELNSQFAFGTSMANSNSFDLSFTSFKERFNTENNLDIDVHFNVPHKYLLKNLESIKHHLQIDNNTIWKQAFINFAGQLLLYFENLQVFAQEASTLQVNAIVIKQDAYFIVEVMKGYNYDNNCICLLEANKDQNVGLTTASTNTLIGDIKQYEPCFFIEK
What are the official names of this protein?
Uncharacterized protein MG343 homolog.
Protein: FABV_XANC5
Sequence: MIIHPKVRGFICTTTHPLGCERNVLEQIAATRARGVRTDGPRKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNLAAFDKHAKAAGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVVYSLASPVRKLPGSGEVKRSALKPIGQTYTATAIDTNKDTIIQASIEPASAQEIEDTVTVMGGQDWELWIDALEGAGVLADGARSVAFSYIGTEITWPIYWHGALGKAKVDLDHTAQRLNARLAKRGGGANVAVLKSVVTQASAAIPVMPLYISMVYKIMKEKGLHEGTIEQLDRLFRERLYREDGQPAQVDDANRLRLDDWELRDDVQGACKALWPQVTTENLFELTDYAGYKHEFLKLFGFERTDVDYDADVETDVKFDCIELA
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: HMPB_DROME
Sequence: MQEVCSSLDTTSMGTQIKSESPLNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENSTPSLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQLHPQQQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQNDHFYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGPVNGPSNFNNGAYYDNMSFQQQAQAHQHQTVVFQQQQPHQPAAINHQHMHHLGNGETYSALGLQMENCEGYNNFGAAGTGGGYYEAGQQPPIPATHGHGHHPHHVQVPAQAHAPIHAHHNSAAIPGGVGVGPPPSHIHGFAINGGPAVQGQAFGNNGSTAAGTAAISGLENSNSSDFNFLSNLANDFAPEYYQLS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Controls development of mouthparts, and labial and maxillary palps.
What are the official names of this protein?
Homeotic protein proboscipedia.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: WHIA_LEVBA
Sequence: MSYASEVKKELTTLEVHRENAKAELVALIRMNGALGLANRHFVLNVQTENPAIARRMYQLLKQFYDLESELLVRRKMKLKKNNLYIVRVKTGVTEVLSDLGIFDGMQLLESVPNEILDDDMRVRSYLRGAFLAGGSVNNPETSRYHLEIYSLYEEHNQVIADMMNRYELNARTIVRRSGYITYLKGAEKIADFLSLIGATTAMLRFEDVRIMRDMRNSVNRLVNCENANLDKVANASTRQIDNIEFIDATVGLGQLPTKLREVAEARLEHKEVSLKELGDLVPGGPISKSGINHRLRKINDYAKQLREEATA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RS16_THEYD
Sequence: MVRIRLMRLGAKKKPFYRVVVADAKARRNGPFIEIIGTYNPKTDPPEVNLNMERVNYWIDKGAQPSDTVKKLIERVSA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL34_ACTPJ
Sequence: MKRTFQPSVLKRARTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TPPP3_RAT
Sequence: MAASTDIAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKAVTGTDVDIVFSKVKAKSARVINYEEFKKALEELATKRFKGKTKEEAFDAICQLIAGKEPANIGVTKAKTGGAVDRLTDTSKYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKK
What is the function of this protein?
Regulator of microtubule dynamic that has microtubule bundling activity (By similarity).  Required for embryo implantation; possibly by regulating beta-catenin (By similarity).  Also required for decidualization via regulation of beta-catenin (By similarity).
What are the official names of this protein?
Tubulin polymerization-promoting protein family member 3.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: DAPAT_PROMP
Sequence: MVKVNENYLKLKAGYLFPEISKRVNNYTQANSSSKVIKLGIGDVTEPLPKACVKAMGEALNEMGTNNGFKGYGPEQGYGWLREKISVNDFISRGCQISSEEIFVSDGSKCDSSNILDILGSDNLIAVTDPVYPVYVDTNVMTGRTGETLQNGTYQGLVYLAINEENKFQPEIPKKKVDIVYLCFPNNPTGATITKQELKKWVDYAIENKSLILFDAAYEAFIQDKNIPHSIYEIEGAKNCAIEFRSFSKNAGFTGVRCAYTVIPKNLSGQNSKGDKIDLWSLWNRRQCTKFNGVSYIVQRGAEAVYSSQGKKEVNSLIDFYMKNAEIMQNKLRSAGFKVYGGDNAPYVWIKVPDRMTSWDFFDYLLEKADVVGTPGSGFGLAGEGYFRLSAFNSRMNVNNAMERIINI
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: VF183_ASFB7
Sequence: MSVVVGGVEYSLNNWARYEIKRRAAELESVNYYPHCEYIMPEDIVVSILGSKPNCPFLEALKRFHDFLKKRRIIFKGEYLVIPWMGAQDVADMIHHVENRINLDHLEDLAHMLKLITYHKSFDTCINQAFEHLYAFKFPDANIETHELKHIRQLEKKMYGYILRLEKLQTVLTFYIEFLLKQV
What are the official names of this protein?
Uncharacterized protein S183L, pS183L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus S183L family.
Protein: XGPT_SODGM
Sequence: MSEKYVVTWDMLQIHARTMAKLLLPAEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCIASYDHDNQRDLNVLKRAEADGEGFIVVDDLVDTGVTAKAIREMYPKAHFVTIFAKPAGRPLVDDYIIDIPQNTWIEQPWDMGVVFVSPLAGK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMN_ECOK1
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_NOTNE
Sequence: MSTKEKLISHVMKEEPVGSRNKVTVVGVGMVGMASAVSILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVGDKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGVSLQGLNPQMGTEGDGENWKAIHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESIIKNMHKVHPVSTLVQGMHGVKDEVFLSVPCVLGNSGLTDVIHMTLKAEEEKQVQKSAETLWGVQKELIL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_DEHMB
Sequence: MNVKIKKLHNWDMTPTEAILLQRELAQKVSACGTLSSISLVAGADVWHSRTSGMGRAAVVVLSYPDMNLVEVSRSEGDCHIPYIPGLLSFREMPLLLSAFEGLESMPDLILMDGQGLAHPRRLGIASHLGLFLNKPVIGCAKSRLVGEYTPLADEAGSYSDLYHNSQLVGRVLRTRRGVNPLFISVGHKICLEEACSRVADCCRGYRLPEPLRHAHLAAAELI
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_CERSK
Sequence: MTVLERLAATVEARKGVDPDSSWTAKLLARGPEKCAEKFGEEAVEAIIEAVRGDRDRLASEAADVLYHLIVMLAARDVTLAEVMAVLEAREGTSGIAEKAGRG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CHLMU
Sequence: MGLKRVVVIGLGLSGKSIARFLARKGVYVLGVDSSIQALQHCPYIHEKLLETDEFPTQVDYVVRSPGISKDHPWVKAARAAQISVVTDIQLAFQTKEFIEQKSFGITGTVGKTTTILFLEYLLRKAGIPAFAMGNVGVPILDGMQNSGVRLVEMSSFQLADQETSYPVLSGGMILNISDNHLDYHGSFLEYCQSKQNLSLCMRNPEDLWVGDQRFCGRSYWEEVQKYMRLLDKESALKPLYLHDKYNYCCAYLLAQAEFPIAKSLFIEAVATFKKPSHRMEYLGEKCGVHYINDSKATTVRATEKALLSIGSRAIVILGGRNKGYSFVSLLPSLRRFAKSVVAMGECAQEIAQDLDGFPVTVVRNLHEALLCAEEQAIPGDVVLLSPACASFDQFRSYEERGAIFKQLVGMEEVLL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRNL1_HUMAN
Sequence: MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCALDALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPDEDVDESES
What is the function of this protein?
Involved in pre-mRNA splicing process (PubMed:11991638, PubMed:12084575, PubMed:28076346, PubMed:28502770).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).
What are the official names of this protein?
Crooked neck-like protein 1, Crooked neck homolog, hCrn.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with core spliceosomal snRNP proteins (PubMed:12084575).
Protein: PRIL_PYRFU
Sequence: MLDPFSEKAKELLKEFGSMNEFLQAIPSLVDIEEVMNRLKFAKESEISEDILNIEDIRDLASFYAQIGALAYSPYGLELELVKKANLRIYTERIRRRRKIRSDEIGIEVKIAVEFPENDIKTLEKVYGGLPEYIVSLREFLDLVPDEKLSSYYVYDGNVYLRKDDLLKVWSKAFERNVEKAVNIIYEIRDELPEFYRRLAGEIRSFAEKEFSDKFREVQAGELKHHLFPPCVKNALRGVPQGMRNYAITVLLTSFLSYARICPNPPRRNVKIRDCIKDMRVITEEILPIIIEAGNRCSPPLFEDQPNEIKNIWYHLGFGYTANPTLEDSGNSTWYFPPNCDKIKANAPQLCTPDKHCRYIRNPLTYYLRRLYLEEKRRAKHADEGSDKGGKERILQ
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL, DNA primase 46 kDa subunit, p46.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: ACT2_BACDO
Sequence: MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESSGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-2, muscle-specific.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.