PharMolix/UniProtQA huggingface dataset:
Protein: MED18_YARLI
Sequence: MQQISLYAKISNSQLKICLHALASLTGMDPITILQHTMVWAPAQKYTPKILPGQGGQLDQYRIHVTNDNKNEDKEKIISYVQSKDSKEDIHNLANRQWHFQIMEMPEAGKQKTTSQSISSWSVKKGDSFQFLQSLAYKFQYEYWQKGFQFVYGNAVIQLTRIHILDQTTKNIKLLDPSKQWLVKVYIDVGHLTDIEALNKAVKELEKVKTELHGLMNLEIPDRNAFDTRIR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFP_HALED
Sequence: MAQHNAFYAQSGGVTAVINASACGVIEACRRHDDRIGKVYAGHNGIIGALTEDLIDVSQESDEAIAALRHTPAGAFGSCRYKLKDIETHRTQYERLIEVFRAHDIRYFFYNGGGDSADTCLKVSQLSEKMGYPLTAIHVPKTVDNDLPITDNSPGFGSVAKYIATSTLEASLDIASMCATSTKVFVLEVMGRHAGWIAAAGALAGQGEGDPPHLVIFPEIDFDRAAVMARVEESVKKCGYCVIVVSEGARYEDGTFLADSGNTDAFGHRQLGGVAPTLAGMIKQDLGYKYHWAVADYLQRAARHLASKTDVDQAYAVGEKAVELALDGQNAKMPAIKRISDEPYAWTVEAAPLADVANREKFMPRDFIREDGFGITEQCRRYLAPLIQGEDFPPFENGLPKVAKLAKHRVERKLPEFKL
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, 6-phosphofructokinase, pyrophosphate dependent, PPi-dependent phosphofructokinase, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSAB_ECO57
Sequence: MMMNSFFPAMALMVLVGCSTPSPVQKAQRVKVDPLRSLNMEALCKDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR
What are the official names of this protein?
Uncharacterized lipoprotein YsaB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PRT2_BUFJA
Sequence: MPPRRKRVSSAPRRRRRTYRRTTAHKHQERPVHRRRRRRH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-2, P2.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: IF2P_PYRAR
Sequence: MAGVRSPFVVVMGHVDVGKTLLLDKIRGTSVAYREPGMITQHIGMSFVPWQAVEKFSGPLVDRLRLRGRIWIPGFLFIDTPGHAAFSNLRKRGGSVADLAILVVDITSGLEDQGVESLKLIQSRGVPFVIAANKLDRIYGWKSVENRPFLFAVEDQEWHAVATLEERIGKLIEELSKFGIEADRYDRVRDFTKQVPIVPTSAVTGEGIADLLLVLAGVSQRFIPKEKLQVGEGPARGVVMEVKEERGLGVVADAIIYDGRLRKGDVVVTAGLEGPKEAKVRMLIMPKPLEEMRDPEDRFMAVEEVKAAAGVRIVADGLEGVVAGAPLLAVWSLQDLPNARRLVGEEISEIKIESDREGVIVRADTFGTLESTVLFLRQQGVPVRKADVGPPTHKDVVEAVLSRRKNPAFGVILAFNVKIPPDVEKEATSSGIKIIRGEILYRIFDEYLKWSQEVKTKTIEQILSQLTRPGKIQILPGFVFRRSDPVIVGVKVLAGTIKPGVTLVKDGREVGKIMQIQKQGKPVNEAAVGDEVAISIQGDVMVGRQIKEGDVLYVYVPDEQAREWLFKYKQYLRDDEKKALEEFLKTRKSAHQ
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: RL18_METMA
Sequence: MATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYSSAVSSELAKYGYTGATGNTTAAYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAALKGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPEQFEATKEKIFAEFS
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RS28_METMP
Sequence: MADDMVYQEAVAAEVIQVNGRTGVTGEIFQVRCKILGGKDTGRILTRNVKGPVKLGDLIMLRETEREAKQLGKRRK
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: MIAA_CAMJE
Sequence: MFFEIALIGTTASGKTYIANTLAREFNAVVLSLDSLCVYKEINIASAKPSQDDLASIKYFGVNLLSVNEHFNVELFIREYQKAKEFALARNLPLIIVGGTGFYLKTMIDGLSEKTLESKSSLNNDEIYALLLNIDPNYKIEKNDTYRLKKWLGIYEQTREIPSEFLKRTQKTGVLKDIEIYELAWDKEILKKRIKTRTKEMLDNGLLDEAKILFSKFDHKLKALNSIGLKECKEYLDGEISFKELENLITIHTTQLAKRQRTFNKKFQSKALEFDKALATLRMKFSIEK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: LPFD_ECO57
Sequence: MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLPDVLNWSNGQNVSLICECPDSYKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNIRISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSFAITKPFIGDSVIPLTLIAELYASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGATEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDSSSTTLLNLSSLDSKTHRNAAIRLLALPISTTGKAPKGGTFEGVTTIYLEME
What is the function of this protein?
Part of the lpfABCC'DE fimbrial operon.  LP fimbriae may participate in the interaction with eukaryotic cells by assisting in microcolony formation.
What are the official names of this protein?
Probable minor fimbrial subunit LpfD.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: NEK8_RAT
Sequence: MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNIHTDVGSVRMRRAEKCLTPGTPMAPGSTGSRATSARCRGVPRGPVRPAIPPPLSSVYAWGGGLSIPLRLPMPNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGTGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSADGELFAWGRGDGGRLGLGTRESHNCPQQVPMVPGQEAQRVVCGIDCSMILTSPGRVLACGSNRFNKLGLDCLSLEEEPVPHQQVEEALSFTPLGSAPLDRETLLCVDLGTAHSAAVTASGACYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAIGAEGEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
What is the function of this protein?
Required for renal tubular integrity.  May regulate local cytoskeletal structure in kidney tubule epithelial cells.  May regulate ciliary biogenesis through targeting of proteins to the cilia.  Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Predominantly cytoplasmic. Localizes to the proximal region of the primary cilium and is not observed in dividing cells (By similarity).
Protein: RPOL_BPT7
Sequence: MNTINIAKNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARFRKMFERQLKAGEVADNAAAKPLITTLLPKMIARINDWFEEVKAKRGKRPTAFQFLQEIKPEAVAYITIKTTLACLTSADNTTVQAVASAIGRAIEDEARFGRIRDLEAKHFKKNVEEQLNKRVGHVYKKAFMQVVEADMLSKGLLGGEAWSSWHKEDSIHVGVRCIEMLIESTGMVSLHRQNAGVVGQDSETIELAPEYAEAIATRAGALAGISPMFQPCVVPPKPWTGITGGGYWANGRRPLALVRTHSKKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVITKWKHCPVEDIPAIEREELPMKPEDIDMNPEALTAWKRAAAAVYRKDKARKSRRISLEFMLEQANKFANHKAIWFPYNMDWRGRVYAVSMFNPQGNDMTKGLLTLAKGKPIGKEGYYWLKIHGANCAGVDKVPFPERIKFIEENHENIMACAKSPLENTWWAEQDSPFCFLAFCFEYAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDEVGGRAVNLLPSETVQDIYGIVAKKVNEILQADAINGTDNEVVTVTDENTGEISEKVKLGTKALAGQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQVLEDTIQPAIDSGKGLMFTQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKTGEILRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLMFLGQFRLQPTINTNKDSEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSFGTIPADAANLFKAVRETMVDTYESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLRDILESDFAFA
What is the function of this protein?
Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes.  Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short transcripts are synthesized and released before proceeding to the processive transcription of long RNA chains.  Unwinds the double-stranded DNA to expose the coding strand for templating.  Participates in the initiation of viral DNA replication presumably by making primers accessible to the DNA polymerase, thus facilitating the DNA opening.  Also plays a role in viral DNA packaging, probably by pausing the transcription at the right end of concatemer junction to allow packaging complex recruitment and beginning of the packaging process.
What are the official names of this protein?
T7 RNA polymerase, DNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
Protein: DHH_HUMAN
Sequence: MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPGGAVQPTGMHWYSRLLYRLAEELLG
What is the function of this protein?
The dually lipidated desert hedgehog protein N-product is essential for a variety of patterning events during development (By similarity).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (PubMed:11472839, PubMed:33063110).  Required for normal testis development and spermatogenesis, namely for the formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules (By similarity).  Activates primary cilia signaling on neighboring valve interstitial cells through a paracrine mechanism (By similarity).  May induce motor neurons in lateral neural tube and may have a polarizing activity (PubMed:11472839).  Prevents the desert hedgehog protein precursor binding to PTCH1 (PubMed:33063110).
What are the official names of this protein?
Desert hedgehog protein, DHH, HHG-3.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Desert hedgehog protein N-product]: Cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Desert hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Secreted. Cell membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane.
Protein: FA78B_HUMAN
Sequence: MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK
What are the official names of this protein?
Protein FAM78B.
What is the protein family that this protein belongs to?
Belongs to the FAM78 family.
Protein: UVRB_STRPS
Sequence: MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IZUM4_MOUSE
Sequence: MFGQGRLGQAMALLLFLGMTAALARGCLQCDPNFAEKFSFYRHHVNLKSWWVGDIPVSGMLLSDWIQNTMKELHLAIPAEITRKKLYQVAEAVYQRMDQLYQGKMYFPGYFPNELRAIFREQVRLIQNAIIESRIDCQRHCGIYQYETISCSNCTDSHVICFGYYCKSSAQWESAVQGLLKYINTWHKQDEKMRTTPAFLSQNIKCLEPQHLVNLTLEKVSECLTQH
What are the official names of this protein?
Izumo sperm-egg fusion protein 4.
What is the protein family that this protein belongs to?
Belongs to the Izumo family.
What are the subcellular locations of this protein?
Secreted.
Protein: FETP_LEGPA
Sequence: MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSEKPSGYKEIK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: 5HT1F_CAVPO
Sequence: MDFLNSSDQNLTSEELLHRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPKQAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYKAAKTLYHKRQASRIAKEELNGQVLLESGEKSIKMVSTTYVPEKSLSDPSTDFDKIHNTVKSPRCKLRHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCEKCKISEEMANFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCQY
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
5-hydroxytryptamine receptor 1F, 5-HT-1F, 5-HT1F, Serotonin receptor 1F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCCT2_VIBPA
Sequence: MSTDNNGGIKRPDGKVNAIDTDYQIGQDNVALKVGPFGLDIHNRVFAISGMAIVLFVVATLTFRQQVEPFFAGLRAWLVSNLDWFFLASGNVFVIVCLVLIVTPLGRVRIGGTEATPDYSYAGWLAMLFAAGMGIGLVFFGVSEPMSHFSSALGGVNIENGVRTDWAPLGGAVGDTDAASALGMAATIYHWALHPWSIYALLALGLAIFSFNKGLPLTMRSIFYPLFGERVWGWVGHIIDILAVVATVFGLATSLGYGASQAATGLNFLFGVPMTDTTQVVLIVVITALALISVVAGLDSGVKRLSEINMILAAMLLFFVIIVGPTMAILTGFFDNIASYITNIPALSMPFEREDVNYSQGWTAFYWAWWISWSPFVGMFIARVSRGRSVREFIICVILIPSTVCVLWMTAFGGTAISQYVNDGYEAVFNAELPLKLFAMLDVMPFAEITSVVGIILVVVFFITSSDSGSLVIDTIAAGGKVDAPTPQRVFWCTFEGLVAIALMLGGGLAAAQAMAVTTGLPFTIVLLVATVSLIKGLMDEPRLSTKAVKKDK
What is the function of this protein?
Involved in the uptake of osmoprotectants.  Can transport glycine betaine, proline and choline.
What are the official names of this protein?
Glycine betaine/proline/choline transporter VP1723.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_YERPG
Sequence: MVAITAALVKELRERTAAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRIAAEGIILAKVSADGKYGVILELNCETDFVAKDAGFKAFGEEVINAALAEKIADIDVLKAKFEEQRANLVAKIGENINIRRVAVLEGDILGTYLHGARIGVMVAATGADEELVKHIAMHIAASKPEYVKPDDVPAEVVAREHQIQLDIAIESGKPREIAEKMVEGRMRKFTGEVSLTGQNFVMDPSKTVGDLLKENNADVVNFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BACCZ
Sequence: MGQKVNPIGLRVGVIRDWESRWFAEKDYATLLHEDIKIREYINVRLKDSAVAKVEIERAANRVNVTIHTAKPGMVIGKGGTEVEALRKALNQLTGKRVHINILEVKRADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRAGAKGIKTQVSGRLGGADIARAESYSEGTVPLHTLRADIDYAAVEADTTYGKLGVKVWIYRGEVLPTKKKASEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RIMP_PROMS
Sequence: MNKENKSKLEALLEKVANERDLEICGLNIQTNQNPVVIEITIRKTNGDDISLDDCALFNTPASDEIEKSNLLNCSYVLEISSQGVSDELTSERDFKTFKGFPVNVELNQKNSKIKILNGLLYEKSKDYLAINIKGKIKKIPFDEVLKISLCTLKD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHN_HALHL
Sequence: MTESASCHGGGVCGGLAQEEGQRQVFCGLTSIVWLHRKMRDAFFLVVGSRTCAHLLQSAAGVMIFAEPRFATAVLGERDLAGMADCNEELDRVVHELLARRPEIRTLFLVGSCPSEVIKLDLGKAAERLTAAHEGRVRVLPYSGSGLETTFTQGEDQFLTTLAHELPASPEGAPSLIVLGTLADVVEDQFRRLFDQLGIGPVHFLPPRTGADLPPVGPGTRVLQAQPFTGEATRALIRRGAERLDAPYPLGVEGTRSWLQAATRSFGVPDEQLEAVIEAPIARAQAALERQRGVLSGKRITFLPDSQLELPLARFLSEECGMQPVEVATPYFDREFHGRERDALGEEVRLVEGQDVDAQLDRLRADRPDLTVCGLGLANPLEAEGLRTKWSIELVFSPIQGFEQAGDLAELFARPLVRHETLKV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: PROA_SULSY
Sequence: MDSRQYAENIAKKAKNTVRKLSSLTTKTKNDALLRTAELLLERKSQIIEENKKDLELAEKKGYSKALLDRLALDDKRINQMVQVLKDVAALPDPVGEIINMWTRPNGLKVGQMRVPLGVILIIYEARPNVTIEAASLCMKSSNAVILKGGSETINSNRILVDIIKQACRETCFPEEAVQFVDTTDREVVNHLLKLEGLIDVAIPRGGESLIRAVAENSKIPVIKHYKGVCNLYVDDEADMEKALNIAYNAKVQRPSVCNAIENLVVHKKIADKFLPEIAYYFGKAGVEMRCDEYSYNLLINHPKAKDTEIVPAKEEDYYEEFLDLIIAVKVVDSLDEAIDFIEKYGSHHSDAIVTENYTKGMKFIQDVDSAAVYINASTRFTDGNEFGLGAEMGISTDKIHARGPMALKELTIPKFIVFGNGQLRENVGIPKDESEIKIDTNACSL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_ROSDO
Sequence: MSTSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPIMPGVTIVEAMAQTAAVMVGVTLEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRGKPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71AS_ARATH
Sequence: MILISLCFTTFLAFLFLNPLLKRTTTTKPNQPPSPWRLPVIGYLHQLSLHPHRSFRSLSLRLWSAHAPSLRSCPYPRFSKYISSSDVAHDVMKTHDLKFANRPKTKAVDIIINGGRDVAFSSYGEYWRQMKSLCTVHLLGRQMVRSFEKVREEEITSVIWKLEKQSSSSLPVNLSDLLLNMSNDVICRIAVGRKYSREENTSDFENQLRKVMELLGAFPVGDYIPGLAWIDKVRGLDRKMEEVSKTFVEFLERVVQEHVDEGENKETFDFVDILLIQLEKTNEFELERSDIRLIILEFFLGGTTTTFTAIDWAMTLVVRHPESMKKLQEEIQTYSRNKLYVPEEEVENMKYLKAVIKEVFRLHPPGPLSIPRQLSEDVKLKDMIIPAGTMIIVFINAWAIHRDTEKWGPYAEEFKPERHLDLPLNFQGQDFNFIPFGSGRRLCPDIDFATMLIEVGLANFVYRFNWRVETRPLGDDDGLKQTGMEVCHKFPLIAFPSLASFTI
What are the official names of this protein?
Putative cytochrome P450 71A28.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1549_MYCTU
Sequence: MVAAPCFRVLRLWTYAHRCDLGHTDPLSRRTEMTTTERPTTMCEAFQRTAVMDPDAVALRTPGGNQTMTWRDYAAQVRRVAAGLAGLGVRRGDTVSLMMANRIEFYPLDVGAQHVGATSFSVYNTLPAEQLTYVFDNAGTKVVICEQQYVDRVRASGVPIEHIVCVDGAPPARSR
What are the official names of this protein?
Uncharacterized protein Rv1549.
Protein: MNMA_CERSK
Sequence: MLDHPLNSLGFAKPPAATRVVVAMSGGVDSSVVAAELAAEGYDVVGVTLQLYDHGAALAKKGACCAGRDIHDARRVAETMGFPHYVLDYENTFREAVIDEFADAYLAGATPVPCIRCNERVKFKDLLQTAKDLDADCMATGHYIQRKMGPAGPELHCAADPARDQSYFLFSTTPEQLAFLRFPLGHLASKAETRALAARHGLPVADKPDSQDICFVPNGNYAEVIQKLRPGAADPGEIVDLSGRVLGEHRGVIHYTIGQRRGLGIGGLGDPLYVVRLDPERRQVIVGPKEALSTRIVPVREINWLGDAPLTSRSEWQVMAKVRSTRASREAVIRPLSDTEAEVELIAPEDGVSPGQACVFYAPGDSRILGGGWIWRGAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.