PharMolix/UniProtQA huggingface dataset:
Protein: CD70_HUMAN
Sequence: MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP
What is the function of this protein?
Cytokine which is the ligand for CD27.  The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses.  Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
What are the official names of this protein?
CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein.
Protein: SYV_LEGPA
Sequence: MDKTYSPEAIEKALYKKWESHHYFQPRGEGKRFCIMLPPPNVTGSLHMGHGFQHTIMDALTRYHRMLGDKTLWQPGTDHAGISTQLVVERQLEAQGVSRKDLTREQFLDKVWQWKEESGNTITQQMRRLGASVDWSRERFTMDEGLSAAVQKVFVQLYEEGLIYRGTRLVNWDPKLGTAVSDLEVLSEEEDGFLWHIRYPVVDSEEFLIVATTRPETLLGDCAVAIHPDDSRFRHLIGKQVHLPLCDRTIPVIADDYVDKEFGSGCVKITPAHDFNDHEVGKRHQLPQINILTKKGTINKNAPLKYQGMDRFVAREQIIKDLEKEGLLAKTEPHKLKVPRGEKSNVIIEPLLTDQWYVKTKPLAEPAIAAVKKGDIRFIPETWDKTYFQWMDNIEDWCISRQLWWGHRIPAWYDNHGNIYVGYSENDVRFKHKIDQSTPLKQDEDVLDTWFSSALWPFSTLGWPERTPELEQFYPTSVLVTGFDIIFFWVARMIMMGLKFTGKIPFKEVFITGLIRDSEGHKMSKSKGNVLDPLDIVDGIDLDSLIAKRTSNLMLNSVRDRITKATRKEFPEGISAYGTDALRFTYCSLASTGRNVRFDLGRVEGYRNFCNKLWNAARYVLLNTDEEQIDFGDGAFQYSPADQWILSRLQNTVSKVHHYFETYRFDLLANTLYEFVWHEYCDWYLELSKPILQDDQALSAMKRGTRRTLIHVLDQILKLLHPLMPFITEEIWQKTTKFTSENGISIMLSTYPKVNEEFINPAIEEELDWLKSAIQSLRTIRSEMSISPAKLIPLYIRNITPELKERIAKYEKILKTLSKIDKINYLAPDEKVPVSATAVLGEIELLIPMADLIDKEAELSRLNKELAKLNKDIELAQGKLNNPKFTDKAPEEIIAKEKDKLAQAQVAKDKLLQHKNRIESL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMB_ECO7I
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAVAIKRPQLKGLINGVLRQFQRQQDELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVQLETPAPVHALPGFEEGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_HAEIE
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGTRAQKTRAEVSGSGKKPWRQKGTGRARAGDIKSPIWRSGGTTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFELDAPKTKVLVQKLKDLAVEDALIITASLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVIVTVDAVKQIEEILA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PHNX_SALPC
Sequence: MMNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPAVDARWQAKFSRSMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIAALRAEGIKIGSCSGYPRAVMERLVPAAAGHGYCPDHWVATDDLAAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPEVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: CYT3_WISFL
Sequence: YGNTGGYTPVPDIDDIHVVEIANYAVTEYNKKSGVVAGVNYRFVLK
What is the function of this protein?
Inhibitor of papain.
What are the official names of this protein?
Cystatin WCPI-3.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
Protein: RIBV_MESFL
Sequence: MDKKYKLWNYKYDFSEINLKNWKEVLKDTFKLNTRKIALLSMLFAIEILMTIISKVIMGLAIPMIVGVYTIEISFFVILIIYLCSNYIYASILSITAIWFRLLLGSEPVGLLSMMISDTAFLTIFAVLFFILKKFIFLKFKFKNQIKILIALICFAGLISMIGSGFISMLCNDKFIFEMYYLSDDGSGYWKMLLWVGFGVTLAKYSINILLFASTLKVLLILIKQSRV
What is the function of this protein?
Probably transports riboflavin.
What are the official names of this protein?
Putative riboflavin transporter RibV.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR4_TUPAK
Sequence: MSKYRGPRLRLVRKLGKLPGLTSKISKKTNTPGEHGQPQNKLLKNRSPYGLRLLEKQKLRFNYNITERQLLRYVKQAKNLTGSTGEILLAILEMRLDNIVYRLGMAPTIVAARQLVSHGHILVNKQKVNIPSYPCQLKEVISVKDKKASRDLVKKFVQESAVNPVPSHLSFNKENLVGIVNNVATREWIGLQINELLVIEYYSRN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARFN_ARATH
Sequence: MESGNVVNTQPELSGIIDGSKSYMYEQLWKLCAGPLCDIPKLGEKVYYFPQGHIELVEASTREELNELQPICDFPSKLQCRVIAIQLKVENNSDETYAEITLMPDTTQVVIPTQNQNQFRPLVNSFTKVLTASDTSVHGGFSVPKKHAIECLPPLDMSQPLPTQEILAIDLHGNQWRFRHIYRGTAQRHLLTIGWNAFTTSKKLVEGDVIVFVRGETGELRVGIRRAGHQQGNIPSSIVSIESMRHGIIASAKHAFDNQCMFIVVYKPRSSQFIVSYDKFLDVVNNKFNVGSRFTMRFEGDDFSERRSFGTIIGVSDFSPHWKCSEWRSLEVQWDEFASFPRPNQVSPWDIEHLTPWSNVSRSSFLKNKRSREVNEIGSSSSHLLPPTLTQGQEIGQQSMATPMNISLRYRDITEDAMTPSRLLMSYPVQPMAKLNYNNVVTPIEENITTNAVASFRLFGVSLATPSVIKDPVEQIGLEISRLTQEKKFGQSQILRSPTEIQSKQFSSTRTCTKVQMQGVTIGRAVDLSVLNGYDQLILELEKLFDLKGQLQARNQWEIAFTNNEEDKMLVGEDPWPEFCNMVKKIFIYSKEEVKNLKSRKSLSS
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Could act as transcriptional activator or repressor.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Putative auxin response factor 14.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T4G1C_AGEOR
Sequence: MRTIISLLLLSAMVFAVIEAISLEEGLQLFEGERGCVGENQQCADWAGPHCCSGYYCTCRYFPKCICRKDSGK
What is the function of this protein?
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with both the activation and inactivation processes being affected.  The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action).  Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV.
What are the official names of this protein?
U3-agatoxin-Ao1c, U3-AGTX-Ao1c, Beta/delta-agatoxin-3, Mu-2Aga_04.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 03 (aga-4) subfamily. Aga sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IL10_LAMGL
Sequence: MPRSALLCCLILLAGVAASRDQGTQSENSCAHFPASLPHMLRELRAAFGRVKTFFQMKDQLDNMLLTRSLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHGPDIKEHVNSLGEKLKTLRLRLRRCHRFLPCENKSKAVEQVRGVFSKLQEKGVYKAMSEFDIFINYIEAYMTMKMKN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_METM7
Sequence: MQKSEGFRSKTRYKLQKHPRQKGMAPLTRALKCYTEGDRVHVVLDPSVQKGMPHPKFHGKTGVVVAQRGRSFLVRVKDGGKYKDIIARPQHLRESKL
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: ZCH12_MOUSE
Sequence: MASILSRLGSSRGQNSPLPPWAHSMLRSLGRSLGPLMASMAERNMRLFSGRAEPAQGEETFENWLSQVTGVLPDWHMPEEEKVRRLMRTLRGPAREVMRLLQAANPGLDVEDFLRAMKLVFGESESSVTAHSKFVNTVQEHGEKPSLYVIRLEVQLQNAIQAGVFAEREANQARLHQLLVGAEMSTDLRFRLKNLLRVYANEPERLPNFLELIRMIREEEEWEETFINPKRPRRAESVMERALSPMAFQSSPPIMISSIDCNVIEIDDSPDDSDEDVILVEPEDPPLPSSSASSFLGRAVSEDQVLVIESPNIFEIQAPSTSSGAGRKNNRGFGELRRARKRKHTIHCSHCGEEGHSKETCDNESDKGQVFENLIITLQELTHAEERARGAPGEPIGLSEPQ
What is the function of this protein?
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway.  It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex.  It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZCCHC12 family.
Protein: SC6A7_RAT
Sequence: MKKLQEAHLRKPVTPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTERCLEHRGPKDGNGALPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVIYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAIDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM
What is the function of this protein?
Brain specific sodium (and chloride)-dependent proline transporter (PubMed:10414958).  Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals (Probable).
What are the official names of this protein?
Sodium-dependent proline transporter, Solute carrier family 6 member 7.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A7 subfamily.
What are the subcellular locations of this protein?
Synaptic cell membrane; Multi-pass membrane protein.
Protein: VE8E2_HPV28
Sequence: MAKHSTREIPAAGPLCTGDTTKASTETSVGATEGPQQKRQRLETLNWEQQQRQYPQTPSTQTTERASQPLDVTRTSDCDTTCPYTVGHPSDPDCAPVVHLKGDPNCLKCFRYRLHKGKRKLYCKTSSTWRWSCESENQAAFVTIWYTSYSQRNEFLSTVKVPPGIQVILGHMSMFV
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RS10_FRAP2
Sequence: MAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKEKFTILISPHVNKKARDQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NUC2_NEUCR
Sequence: MKFGKQIQKRQLEVPEYAASFVNYKALKKLIKKLSATPILPPQTDLRRAPGEPLDTQSALQANKATFFFQIDRELDKVNACYVQKEAELKIRLKTLLDKKKALRSRSGGTSRRSTKFTTLQEGFQQFVNDLNKLQQFVEINGTAFSKILKKWDKTAKSKTKELYLSRVVEKRPAFNPTVISELSDQATTSLQELGAWADGDNVSFETRPDHDHVVSTQHLLGTDEGDADTLLLDTVLSGNIDSLKDMLDRMKATAAPDGSADVSLAERVTRTFLASINEGSLEALKVLLDTGLVDIQSWDDINERNCLHQAAIYGNSFVLEYGLSKGVDAERTDAYGRVPLHYASMHGRLDMIDALLNASPKTINLIDHDNFTPLVHSIVRNHLECVGRLLERSARIDPVSDTDHVPLNLACQHGSVAIVELLLKHGAKILADAEGLYPQHLVARSGQTPEILVLLKQYGADLDQIDKLYGWTPLVHAASEGNVPCLQALLETGADPNILDEKDLPAMYYAAWEGHLECMKLLTPAKKEKAASELPPIHIGGALPPMASSTAPMPMSLDAIDPIPALELPPPIIPLRRYGHNFLDTKTVVQISFEEDSEQPLLFFQDGKYPAARLTISSKSSDLIPKNIILPFQEDTRVASFQIDNLESFTLDFEVFPTYGAKVIAKTVALPNIFRALLSSSGKCCLPLFDPRLRAIGQISFHVQIIKPFSGTPLEITDFETYWKATSQFDTNTSTFVTGSSLSGDFVQIYVQHTKDGVPVLWPRWTINCGGIDVPVSTLTLAQFQTVTAAARNRINLSELSTYTLDQIADVHRILANIGITLHEALFLLPKGMHVNIQVLYPTADEKAEAKSSTAADDVNEFADAILSVVFDHARAQRAERPDSVRSVVFSSYNPTLCTALNWKQPNFPVFLCNDMGREDRKQQQQGSCSKGDGDEDMGGTTAASRREAADERTLQSDGRRTSSIKDVVRTATSNNLMGLICCSRLLDMVPALVDAIKSHGLALVVDKSGEPEAANSKDSGDKQLGISGALGGLAGSDPFPKLPKGVDGLLKSNGVLRFNEYIDV
What is the function of this protein?
Controls phosphorus acquisition.
What are the official names of this protein?
Ankyrin repeat protein nuc-2, Nuclease 2.
Protein: PTNAB_ECOLI
Sequence: MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAETLIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETLMARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPNDYMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTAHVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQVNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK
What is the function of this protein?
Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA.
What are the official names of this protein?
PTS system mannose-specific EIIAB component, EIIAB-Man, EIII-Man.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: TATCD_BACSU
Sequence: MDKKETHLIGHLEELRRRIIVTLAAFFLFLITAFLFVQDIYDWLIRDLDGKLAVLGPSEILWVYMMLSGICAIAASIPVAAYQLWRFVAPALTKTERKVTLMYIPGLFALFLAGISFGYFVLFPIVLSFLTHLSSGHFETMFTADRYFRFMVNLSLPFGFLFEMPLVVMFLTRLGILNPYRLAKARKLSYFLLIVVSILITPPDFISDFLVMIPLLVLFEVSVTLSAFVYKKRMREETAAAA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Required for PhoD secretion.  TatCd promotes membrane localization of TatAd via domain specific interactions.  TatCd is required for stabile production of TatAd as well as for its maintenance.
What are the official names of this protein?
Sec-independent protein translocase protein TatCd.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCF4_NASOF
Sequence: MSWRSESIWIEFITGSRKTSNFCWAFILFLGSLGFLLVGTSSYLGRNVISLFPSQQIIFFPQGIVMSFYGIAGLFISCYLWCTILWNVGSGYDLFDRKEGIVRIFRWGFPGKSRRIFLRFLMKDIQSIRIEVKEGVSARRVLYMEIRGQGAIPLIRTDENFTTREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYM_SHEON
Sequence: MATSQRKILVTSALPYANGPIHLGHMLEYIQTDIWSRYQKLRGHECHYICADDAHGTPIMLKAQQLGMAPEEMIAQVNKEHQQDFADFNIAFDNYHSTHSEENRVLASDIYLKLRANGYIKSKSISQLFDPEQSMFLPDRFVKGTCPKCKSPDQYGDNCDACGATYSPTELINPKSAVSGATPVMKDTEHFFFDLPAFEDMLKEWTRSGALQTEMANKLDEWFEQGLQQWDITRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCDKRPELSFDEFWAKDSKAEVYHFIGKDIVYFHSLFWPAMLYGSGYRQPNSVYAHGYVTVNGAKMSKSKGTFIKARTYLDHLDPEYLRYYYAAKLSSRIDDLDLNLEDFAQRVNSDLVGKLVNLASRTAGFITKRFDGKLAKITDTTLTEVFLAKQEQIAEFYETREYGKAMREIMALADIANGFVADAAPWQMVKHDDQQEAAHQVCSNALNLFRILVTYLKPVLPRLAQDVEAFFQQTLTWDGLGQDMAGHEIAPFKAMMQRVELDKVNAMVADSKENLQATTEPEAPKGPLATDPISDTINYEDFAKIDLRIARIVKAEHVAEADKLLKLQLDIGGETRQVFAGIKSAYSPEDLEGKLTVMVANLAPRKMRFGMSEGMVLAAGPGGSDLWILEPHEGAQPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_STRTD
Sequence: MHVIAVDAMGGDNAPQAIVEGVNQALAEFKDIEIQLYGDEAKIKNYLTANERVSIVHTDEKINSDDEPVKAIRKKKKASMVLGAQAVKEKAADAVISAGNTGALLAAGLFVVGRIKGVERPGLMSTMPSFTGQPFDMLDLGANAENTANHLHQYAILGSFYAKNVRGIATPRVGLLNNGTEKTKGDSLRKEAFELLSKEASINFIGNVEAREIMSGAADVVVADGFTGNAVLKAIEGTGLGTMKTLKSAIMNGGLKAKLGAFLLKDRLKGMKETMDYSSAGGAVLFGLKAPVVKCHGSSDAKAVYYTIKQVRKMLDTKVVEQLVDAFDPKEEVN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ODH_YERPE
Sequence: MHNTLPTLILGAGPAAIQLAVDISATGDARLGLYNRPSTKGERLKQYLALTPTLYLQGTGKAQATQKESSVTIDCYIDQLAQAVGDWQRLILAVPADHYYAVLQQIPWAALPQLKSVILLSSSMGSGLMVQNLLNAAGKRDVEVISLSSYYADTKYIRAETQDISANTQDINAGTQDIGAIQPYRAYTKAFKQRIYLANQWGNAGSAEMSWLTAVLARHHIDTLPCSNLLAAERFSITNYVHPPLALADTTLQALFYPEQRSQYLYKTQPEGPVCPAVIADLAGLADDYKRLLNRLGVEEINLLRFLNDDNYPVPASMVSRRWIDEFPQLPPLEQQYALFVRYTALLVDPYSTPDEQGRFYDFSAVKVATVYQDANALWHLPRVPLEDVHKLRTLLLLAGALDVVMPTAQRLLQRFQQALKAFIDRVGEEHCHPSLLGDDCDRQAAIIEQQWRSQT
What is the function of this protein?
Catalyzes the NADPH-dependent reductive condensation of pyruvate to the intermediate formed by the adjacently encoded enzyme y2836, namely (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate, leading to the production of yersinopine.  This is the last step in the biosynthesis of the metallophore yersinopine, which is involved in metal acquisition and thus enables bacterial growth inside the host, where metal access is limited.  Therefore, this enzyme probably contributes to Yersinia virulence.  Cannot use alpha-ketoglutarate in place of pyruvate, and displays only poor efficiency with oxaloacetate and glyoxylate.
What are the official names of this protein?
Yersinopine synthase, Opine dehydrogenase, ODH, Yersinopine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the staphylopine dehydrogenase family.
Protein: Y3519_METJA
Sequence: MESKEFDDDKIKIISMTPKSEKSDKIVMQIVEEFINSFPDDRYKFRVLLKVAELICKNGLCNEAFLILDKIPDSYYKSSALYKMADILYRNKEHDRLIQIAEKIPDDYKKSEVLLKVVELLCESGKYDEAINIAEKIPDNYYKSEALFKIAETLSNKGYYDKAVEIAEKIPDNF
What are the official names of this protein?
Uncharacterized protein MJECL19.
Protein: Y1466_AQUAE
Sequence: MGLNMARKENLVHVLVALILSLSIWFVVNFGERLPLDIVRFVEIQGKREGYVYRVEPQTVDITLIVSRRFLESKLLERVRAIIYVFELKEGTHRVRVDVVSPLPYFIQPVAVNPYYVNVTVIKEKR
What are the official names of this protein?
Uncharacterized protein aq_1466.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GNO_GLUOX
Sequence: MSHPDLFSLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFDVTDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFVGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQINGLAPGYFATEMTERLVADEEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRASSFVNGQVLMVDGGITVSL
What is the function of this protein?
Catalyzes the reversible NADP-dependent oxidation of gluconate to 5-ketogluconate.  Is involved in the non-phosphorylative, ketogenic oxidation of glucose.  Is almost inactive with NAD as cosubstrate.  Displays high substrate specificity since D-Glucose, D-sorbitol, and D-mannitol are not oxidized by the enzyme, and 2-ketogluconate and L-sorbose are not reduced.  Can accept D-fructose as a substrate, with a rate that is only 10% of the rate of 5-ketogluconate reduction.
What are the official names of this protein?
Gluconate 5-dehydrogenase, D-gluconate 5-dehydrogenase (NADP), Gluconate:NADP 5-oxidoreductase, GNO.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_METS4
Sequence: MQVLVRDNNVDQALRVLKKKMQREGIFREMKQRKAYEKPSVRKAREKAEAVRRARKQARKTAIREGLIAAPKPKPRAVAPRRPAAAPAPASSPTTTA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PON1_MOUSE
Sequence: MAKLLALTLVGLVLALYKNHRSSYQTRLNAFREVTPVELPNCNLVKGIETGAEDLEILPNGLTFFSTGLKYPGIKSFDPSKPGKILLMDLNKKEPAVSELEIIGNTLDISSFNPHGISTFTDEDNTVYLLVVNHPDSSSTVEVFKFQEEERSLLHLKTITHELLPSINDIAAIGPESFYATNDHYFADPYLRSWEMYLGLSWSNVVYYSPDKVQVVAEGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLKVLNFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDAENPPGSEVLRIQNILSEDPKITVVYAENGTVLQGTTVASVYKGKLLIGTVFHKALYCDL
What is the function of this protein?
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides.  Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters.  Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
What are the official names of this protein?
Serum paraoxonase/arylesterase 1, PON 1, Aromatic esterase 1, A-esterase 1, Serum aryldialkylphosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the paraoxonase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.