PharMolix/UniProtQA huggingface dataset:
Protein: RNPH_BACC3
Sequence: MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEALGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVSKIPVKDYLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELLDAAEQGIFQLIDIQKEALGDIVSHIE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: HEM2_MYCLE
Sequence: MSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRAAVAAVDAGVGGLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTSIRRAGADIVFTYWAADVACWLS
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: TATB_CAUSK
Sequence: MLPDIGGTELLVIAAVALIVVGPKDLPVLLRKLGQFIGKIRGMANEFRASFDEMARQSELDELRKEVQAMRDGQYTAPMRDAAAQAGDASHVDQVFADIDASLNSGAVKVSPFEAYQAPALEAPEPTVEIVSKPARKPPAKKAAAKPAAKAELVSKPKASAKASKGDLSVPTKPARKRAAKASTNSDITS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLGL3_ARATH
Sequence: MDSCCNFSLGTKTVLAKDSFKNVENKFLGEKIKGSVLKPFSSDLSSKKFRNRKLRPGVAYAIATSKNAKEALKNQPSMFERRRADPKNVAAIILGGGDGAKLFPLTKRAATPAVPVGGCYRMIDIPMSNCINSCINKIFVLTQFNSASLNRHLARTYFGNGINFGDGFVEVLAATQTPGEAGKKWFQGTADAVRKFLWVFEDAKNRNIENIIILSGDHLYRMNYMDFVQHHVDSKADITLSCAPVDESRASEYGLVNIDRSGRVVHFSEKPTGIDLKSMQTDTTMHGLSHQEAAKSPYIASMGVYCFKTEALLKLLTWRYPSSNDFGSEIIPAAIKDHNVQGYIYRDYWEDIGTIKSFYEANIALVEEHPKFEFYDQNTPFYTSPRFLPPTKTEKCRIVNSVISHGCFLGECSIQRSIIGERSRLDYGVELQDTLMLGADSYQTESEIASLLAEGNVPIGIGRDTKIRKCIIDKNAKIGKNVVIMNKDDVKEADRPEEGFYIRSGITVVVEKATIKDGTVI
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase S, Alpha-D-glucose-1-phosphate adenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLGX_ECO45
Sequence: MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNASIAPKCVVVVDHYDWEDDAPPRMPWGCTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQRGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALMENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: NAA10_HUMAN
Sequence: MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
What is the function of this protein?
Catalytic subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase activity (PubMed:15496142, PubMed:19826488, PubMed:19420222, PubMed:20145209, PubMed:27708256, PubMed:25489052, PubMed:29754825, PubMed:20154145, PubMed:32042062).  Acetylates amino termini that are devoid of initiator methionine (PubMed:19420222).  The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development.  Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182).  Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (PubMed:19826488).  Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (PubMed:20145209).  Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (PubMed:27708256).  Acetylates HIST1H4A (PubMed:29754825).  Acts as a negative regulator of sister chromatid cohesion during mitosis (PubMed:27422821).
What are the official names of this protein?
N-alpha-acetyltransferase 10, N-terminal acetyltransferase complex ARD1 subunit homolog A, hARD1, NatA catalytic subunit Naa10.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
Protein: BSDD_BACSU
Sequence: MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESITNPEKYNPAFKIDPKETETAIEVPAVPERKA
What is the function of this protein?
Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise biochemical function of BsdD in metabolism of phenolic acid is unknown.
What are the official names of this protein?
Protein BsdD, Phenolic acid decarboxylase subunit D, PAD.
Protein: GUAC_YERPN
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: FA87A_HUMAN
Sequence: MTGTLERENWISGGKSLVLRKQHPGPLRPWRKRAAQLGGGCGWRTAVAPAKFCLWYVVPSWLWEPPGYLHSSLFLSILFQVTLLETALQSRPNLSLPLVRCGWACTQAMSTRSNCGSRSFLWAQTQADAASGLPRSRLGFLGLGGCGLIVKHGMTLRNWASFFVVFQAWSLMILQVLGDMLNIYYAYIQATLTLKVDVAPRLFFPEGGALKEHFSSMDSFQLREAGGTRIPRPALIYGRAVVTRTVTKAQSLKSALAWAALGCKHPVLSTLCEESQQGAWSEFRRF
What are the official names of this protein?
Protein FAM87A.
What is the protein family that this protein belongs to?
Belongs to the FAM87 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS6_METSB
Sequence: MALYEHIYLARQDVSAQQVETLTEQFRGIIESLGGKIEKVEYWGVKTLAYRIKKNRKAHFTLLNIDAPAAAITEMERQSSLNEDVLRLLTIRVEALEAGQSAMMRKRDDDDRGDRPDRGDRGRGPRPDRPPRRPRDDAAASDEGGF
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SUCC_SALPC
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y2648_BRADU
Sequence: MVERLRIDHVGHRGDGVALGAGEAIYVPYALGGETVEVDHVAGNHPDRRKLLAVDVASPERVAPFCPHFGICGGCAIQHWAAEPYHAWKRSIVVETLAQAGIDCEVAPLVDAHGVGRRRVTLHGRFGTHDILKVGFSAASSHDVIPIHRCPILDPALDGALDAAWALAEPLTSKMPVTKPLDIQVTATTNGLDVDVRGSGPLPTPLVTALSRVAEQHRLARLTRHGELVLQRLPPTVKMGRTEVTLPPGSFLQATVAGEETLASLVAERVGKAKEVLDLFCGVGPFALRLAEKARVTAYDSDAGAVAALAKAARTPGLKPIRCEPRDLFRRPLVPQELRDFDAVVFDPPRQGAQAQALKLAASTVPVIVAVSCNVATFARDARLLIDGGYRIDGVVPVDQFRHTPHVELVARFAR
What are the official names of this protein?
Uncharacterized RNA methyltransferase bll2648.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: TATA_XANOP
Sequence: MGGFSIWHWLIVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDDKPAGKLGDDSRTAEQAREAQAERDRDAR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HASP_HUMAN
Sequence: MAASLPGPGSRLFRTYGAADGRRQRRPGREAAQWFPPQDRRRFFNSSGSSDASIGDPSQSDDPDDPDDPDFPGSPVRRRRRRPGGRVPKDRPSLTVTPKRWKLRARPSLTVTPRRLGLRARPPQKCSTPCGPLRLPPFPSRDSGRLSPDLSVCGQPRDGDELGISASLFSSLASPCPGSPTPRDSVISIGTSACLVAASAVPSGLHLPEVSLDRASLPCSQEEATGGAKDTRMVHQTRASLRSVLFGLMNSGTPEDSEFRADGKNMRESCCKRKLVVGNGPEGPGLSSTGKRRATGQDSCQERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQEATETSLLHSHRFKKGQKLGKDSFPTQDLTPLQNVCFWTKTRASFSFHKKKIVTDVSEVCSIYTTATSLSGSLLSECSNRPVMNRTSGAPSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQKGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK
What is the function of this protein?
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis.  May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
What are the official names of this protein?
Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Protein: PYCC_STAAU
Sequence: MVNHIRIFDNLFQSNISKFQNLTSKSYIIRNDNEKNSYLPMVQEIRELFGKEGEIFSKSIGTHPDFFGIENTNEYQYICSLFVDISGSTKLALKYSLDKVKLYKNAIISSAIEIFRAFDGHIHRIQGDAVLVYFGHKELEKSDAIINAINAASLMQYFNATTLKKFFESENLEPLKIRIGIDFGDDSSVLWSKYGIDGINEITSTSIHTDLASKFQNKAPSNKIMIGENINKYLDIPKKFRSIKIEKNNGVDVEKRYILNTNNLGRYSMEVFEWEKYLNSFSMLPPFSTENEQFYSPRDLKIRCWIIDEKNQDKYEYIERGSALKKEMNLLFKLEIYNQCLEFKNIKWRVVNYGEEAKKDKELEFEMNQYEGYQYCNQKTAYTGLHFMECYLYDINDKIICHDSFGLFINDNNREVRKLGIED
What is the function of this protein?
The pyrimidine cyclase gene of a two-gene Pycsar system, weakly generates cyclic CMP (cCMP) from CTP, has little to no activity on ATP, GTP or UTP (PubMed:34644530).  Expression of this and adjacent effector SaPycTM (AC P0DV39) probably confers resistance to bacteriophage.  The genes are probably only expressed in response to bacteriophage infection (Probable).
What are the official names of this protein?
Cytidylate cyclase, Cyclic CMP synthase, cCMP synthase, SaPycC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Pyrimidine cyclase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CARHZ
Sequence: MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQILTGVRGGFATGAPITIKVKNRDYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHKDLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVLRIGSVEVEYPGGLPEEELKKADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRLAGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPLIAKVSLKPIPTQVKPLKSVDIVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLEKFGGDRIEETKRNYQNYLQSIANY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DNAA_RHOPS
Sequence: MSNMEHDRWSRVKGRLRSSVGEDVYSSWFARMDLEAVQQESVHLSVPTRFLKSWIQTHYSEKVLTCWQAEMPEVCRIDLTVRSPMRAAVTKEAPAPAEHRRDEHRPAADARSHAAAPAPSNHDALGGSPLDPRLTFASFVVGRSNTLAHAAAKQVAEGRRGDPVMFNPLYIHSGVGLGKTHLLQAVTWAGNSGTERKVLYLTAEKFMYGFVASLKTQTSLAFKEALRGIDVLVIDDLQFLQGKTTQAEFCHTLNALIDAGRQVVVAADRPPADLESLDERVRSRLAGGLVVEMAPLGEELRLGILKSRVVAARTHHASFDVPQSVLEYLARAITHNGRDLEGAINRLLAHSKLNAQPVTLEMAEHEVRDLIRPQEPKRIKIEDIQRVVARQYNVSRSDLLSSRRTANVVRPRQVAMYLAKTLTLRSLPEIGRRFGGRDHTTVLHAVRKIEGLVSKDVTLSDEVESLKRQLQE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BORBU
Sequence: MSSKVQQEIADLKKLIRKWDKEYYVDSLPSVEDFVYDKHILRLQELESKYPEYKTLDSPTLKFGSDLLNDFKEVEHSAPILSLDKVYDLDLLKSWIDKIDFNNSFNISVEPKIDGCSIVLYYKDGVLEKALTRGNGKFGNDVTINVRTIRYIPLFLDEKVDLVLRGEVYITKENFLKINKFLEKPYTNSRNLASGILRRVDSREVANFPLNIFIYDFLNAGLEFKTNDLATARLKKLGFKVNPLIRFFDLKNSIGEVLNYIADITKKRDSFEYEIDGVVLKVSDFALRERLGYTAHHPKWAMAYKFEALSGFSRVNSIVVQVGRSGKITPVANIDKVFVSGAFITSATLHNQDYIRSIGLNVGDVVKVSRRGDVIPAVEMVINKFSTGFFKVPDNCPACKTAVVKEGAHFFCPNNNCPSVAVERIKYFCSKNCMDIEGFSDKIISFLFEKKFIFSEIDLYTFDFYKLLEFKGFKDRKINNLINSIEASKKKPFSKLLLSMGIKDLGENTIRLLFLNNLNSFSKLFKLCQDRYFAFSTLLKIKGIGEKIALNIIEAFNDSVMLNKFKFFENLEFKMEEVVAIDGENKLLAGKKFCITGTFNGYSRSIIIDKLKNKGAIFNTCVTGSLDFLIVGEKAGSKLKKALSLNIKIMSFEDIKSYLD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CYB_EQUGR
Sequence: MTNIRKSHPLIKIINHSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGIILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPSGIPSDMDKIPFHPYYTIKDILGLLLLILLLLTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALIPTLHTSKQRSMMFRPLSQCVFWLLVADLLTLTWIGGQPVEHPYMIIGQLASILYFSLILIFMPLASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURI_RALSO
Sequence: MTTRAQAPVGVFDSGLGGLSVLRAIRAELPAESLLYLADSRHAPYGEKPPEFIAGRTLRVCEWLVGQGCKALVIACNTATAQAVHLLREQLAVPVIGVEPGLKPAVATSRSRVVGVLATESTLRSDKFARLLGNVSGDCRVLCQPGYGLVPLIERGDTHSPAVLELLRAYLLPMLEAGADTLVLGCTHYPFLQDAIREIAGDRLTLIDTGHAVARHLGRTLAAAHLQATGAAASPRFLSTADVLPLQAMVAALLGEAPMAQRIDIGDTAVPPLASHQ
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CQ10B_RAT
Sequence: MAARTSQRTLARVASGCRPKSTTVTEARVRGSARNVRYLAPCGILMNRTLAPWASVLPKEICARTFFRITTPLVNKRKEYSERRIIGYSMQEMYDVVSGMEDYKHFVPWCKKSDILSRRSGYCKTRLEIGFPPVLERYTSIVTLVKPHLVKASCTDGKLFNHLETVWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFERRACKLYGPETNIPRELMLHEIHHT
What is the function of this protein?
Required for the function of coenzyme Q in the respiratory chain.  May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).
What are the official names of this protein?
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ASSY_CALS4
Sequence: MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAVCVDVGQREDLRYIKDKALASGASKVYIEDVKEEFVKDYIFPTLKAGAIYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGATGKGNDQVRFEVSIRALDPSIKIIAPWRIWELKSREDEIEYAKKKGIPIPVTKEKIYSVDSNLWHVSHEGGDLEDPWNEPKSDIYDIVTPPEKVSDKPEYVYIEFEKGIPVKVNGKTLSPVKLIEELNEIGGRNGVGIVDLVENRLVGMKSRGVYETPAGTLLYIAHRELEYLVLDKETMRFKELVAQKYADLVYNGLWFSPLKTALDAFIDETQKNVTGVVRLKLYKGNVINAGAKSPYSLYNEEFATFGKDEVYNQKDAEGFINLFGLSLKIRALMEMGRKDMDEAVGR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIC_SHIF8
Sequence: MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGNKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESEWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYMTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQAQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPSDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCDKIWRNLKCPLIWRSEKICHVIARGK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL4_PROM2
Sequence: MTTLETLKWDGKKSGKVTLDLTVAKETSSADLIHRAVLRQLANKRQGTASTLTRSEVRGGGRKPYKQKGTGRARQGSIRTPLRPGGGIIFGPKPRSYNLDMNRKERRLALRTALMSRVSDMKAVEDFGSTLKQPKTSDIINGLARLGIQKNEKVLVILDSPSDVIKKSINNIEKVKLIAADQLNVFDILNANKLLIGQSAIDKIQEVYAS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS26_ORYSJ
Sequence: MTFKRRNGGRNKHGRGHVKYIRCSNCAKCCPKDKAIKRFQVRNIVEQAAIRDVQEACVHDGYVLPKLYAKVHHCVSCAIHAHIVRVRSRENRRDRRPPERFRRREDRPQGPRPGGGAPAPGGAAAPAPNVART
What are the official names of this protein?
40S ribosomal protein S26, S31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS26 family.
Protein: RS8_STRS7
Sequence: MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREGFIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLGIAIISTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL4_EXISA
Sequence: MPKVALLNQTGSQVGEIELAEAIFGIEPNESVLYDAIVMQQASRRQGTHDTKGRSEVRGGGRKPWKQKGTGRARQGSIRSPQWVGGGTVFGPTPRSYSYKLPKKVRRLALLSALSSKVQNNEIIVLEGLAFDAPKTKDMAAVLNSLSVERKALVVTADYNETIALAARNIPGVTVIDAAGVNVLDLVANDKVIFTKDAVAKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.