PharMolix/UniProtQA huggingface dataset:
Protein: NUOK_ERWT9
Sequence: MIPLQHGLILAAILFVLGLTGVTIRRNLLFMLIGLEIMINAAALAFVVAGSYWGQADGQVMFILAISLAAAEASIGLALLLQLHRRSQNLNIDKVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAS20_CAEEL
Sequence: MKITVNFLLVALIGVPSVLSDRHITRDKRQAMRDYAKWENNKMSLFFYNLPLEMQAMFRDAINYLENHTCLKFEYNENAETAVRIRKGNGCYSLYGMHAGEVQDLTLDYNCASFGTAVHEIMHALGIAHGQARSDRDDYLIVDSTNSNDGIENTENLVPFDYGSVMLYARDPHSDKRIPIDPEYNFTMGSLRVAFYDMVLLNKFYGCNCDNHPRKLDCKNGGYQNPANCEECLCTDGFNGQLCDQHEGVYVLEAKKEWDASGVRNNYRKGIETNTMPEYTYFALTAPEGSTIEVRITKLSGFFCQHTCDYNGVELKYKTDRRIVSPLVCCDNDNLWNKTRSSTNNPFIIAKYGNNRTPHFEFEYRYIPGNATAAPEENN
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-20, Nematode astacin 20.
What are the subcellular locations of this protein?
Secreted.
Protein: PRVA_PELLE
Sequence: PMTDLLAAGDISKAVSAFAAPESFNHKKFFELCGLKSKSKEIMQKVFHVLDQDQSGFIEKEELCLILKGFTPEGRSLSDKETTALLAAGDKDGDGKIGVDEFVTLVSES
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin alpha, Parvalbumin pI 4.88.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: ZDH22_HUMAN
Sequence: MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGACQGASARKTPCPSPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESSKQQDK
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (PubMed:22399288).  Catalyzes the palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (PubMed:22399288).  Might also mediate palmitoylation of CNN3 (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC22, Zinc finger DHHC domain-containing protein 22, DHHC-22, zDHHC22.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: AROD_CLOD6
Sequence: MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLDIIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLNKEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLCRMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGEIFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.  The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsilon-amino group of Lys-170 at the active site.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: EFG_AGRRK
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTYWKGRDGKTRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRSVEMIKTRLGATAVVMQLPIGAETEFKGVIDLIEMNALIWRDESLGAQWDVVEIPEDMKAKAEEYREKLIETVVEIDEAATEAYLEGNLPDNDQIRALVRRGTIDVKFHPMFCGTAFKNKGVQPLLDAVVDYLPSPLDIPAIKGIDFKTDAEIERHADDSEPLSMLAFKIMNDPFVGSLTFARIYSGKLEKGASVMNTVKDKRERVGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDQESGQTIIAGMGELHLDIIVDRMRREFKVEATVGAPQVAYRETITRLTEKDYTHKKQSGGTGQFARVKIVFEPNPEGDDFKFESKIVGGSVPKEYIPGVQKGIESVLSSGPLAGFPMLGVKATLIDGAFHDVDSSVLAFEIASRACFREAAREAGAQLLEPMMKVEVVTPEDYVGDVIGDLNSRRGQIQGQEARGIAVVINANVPLANMFKYVDNLRSMSQGRAQYTMTFDHYAPVPSNVAQEIQAKYSGQK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_RHOBA
Sequence: MNNAIMDMVDKANQKENAPQFDIGDTVDVHSKILEGNKERIQVFTGVVIGRSGKGAQEMFTVRRIVAGEGVERKFPVHSPRIEKVEVKRSGVTRRAKLYFLRDRVGKAVRLKERRRV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MMM1_CLAL4
Sequence: MAGKADLGHTGISDNIVERQIFVPQPNNAWSFTQGLMCGQASVVVVLLVFIKFFVFSEAPPSSGAAKSKKKDISGVIVKREAKNTDDDDGVENGDSAKLATILEKTYYDVNNHNPESLDWFNVLIAQTISQLRCEALLSDNIYHSLNDFLETSDLPDFMDKITLTEIDIGDDFPIFSNCRIQHSADGTGRLEAKIDVDLSDTLTLGIETRLLLNHPRPLTAVLPVQLTVSMVRFSGCLTVSLVNTNDTDFVGTSKEENSSGGGTALMFSFSPDYRLEFSVKSLIGSRTKLQDVPKISDLVDSKLRNWFSDRCVEPKFQVVRLPSMWPRSKNTREPVGAGKTEKVNGNE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: YQGE_ECO57
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MGP_RABIT
Sequence: MRSLLLLTVLAALVVAILCYESHESMESYEINPFINRRNANTFMSPQQRWMAKAQERVREQRKPAYELNREACDDYKLCERYAMVYGYNAAYNRYFRQRRRAE
What is the function of this protein?
Associates with the organic matrix of bone and cartilage.  Thought to act as an inhibitor of bone formation.
What are the official names of this protein?
Matrix Gla protein, MGP.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: YHEU_ECOLI
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: KPRS1_STRMU
Sequence: MSYSNLKLFALSSNKELAEKVAKTIGISLGKSTVRQFSDGEIQVNIEESIRGNHVFILQSTSSPVNDNLMEILIMVDALKRASAETVSVVMPYYGYARQDRKARSREPITSKLVANMLAVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFVRRGMCGSDYVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRNVNKMNTSEVMNIIGNVSGKTCILIDDMIDTAGTIAHAADALAEAGATAVYASCTHPVLSGSALDNIQNSAIEKLVVLDTIDLPEEKLIDKIEQISITDLISEAIIRIHEKRPLSPLFEFTTFN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, RPPK 1, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 1, Phosphoribosyl diphosphate synthase 1, Phosphoribosyl pyrophosphate synthase 1, P-Rib-PP synthase 1, PRPP synthase 1, PRPPase 1.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_ACIAC
Sequence: MTIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSLIDARTISVQPWEKGMGAKIEKAIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARNEGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEADIQKVTDKHIAEVDALVAAKEQEIMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDHK_ECOLI
Sequence: MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLDEPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSAWLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGILCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQILTMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREILEQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRLQSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLAAISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLATMQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFAILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARRWLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATLEELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS
What are the official names of this protein?
Uncharacterized transporter YdhK.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_STRPD
Sequence: MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRDDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLTQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQFPDSFVIN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_ALISL
Sequence: MSSFSESAILVRDALVARGLETPMKENGISREEKKERIEEHMREILSLLTLDLSDDSLEETPHRIAKMYVDEIFSGLDYANFPKITVIENKMNCDEMVRVNDITLTSTCEHHLVTIDGKATVAYIPREKIIGLSKINRIVRFFAQRPQVQERMTQQILVALQTLLGSDDVAITMEATHYCVKSRGVMDATSSTTTTALGGIFKRNPATRHEFLSGIR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: END3_ECOLI
Sequence: MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: CBID_SULIL
Sequence: MIINSLKRFGITTGAAASAAAKAAVIGLLNREKRNTVVIPTPIGLRLEIPVEKVEIDSGIACAEVKKFSGDNPDILDGLVIRCCAKLNESNEIVIVGGKGVGKVTRSGLKATMGETAISPTVRDMVINAIREVTDKGIQITIEVPNGDIIAENTLNKMVGIVGGISILGTTGIETPVSDDDYLEHIKCELNVIRQSYDFVVIAPGNSAAKYASKLFDSNSIIKVGDRIGDSIKLASSVFRKVILAGLPAKLLKVYAGIFNTHYSQGDARLESLTHASVLAGLPYDVLTKITNALSVEEAFTYMTKEQRRKVMKIVAEKILSRIKSFNGDINFCVIIFDYDSESLSRVGC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: RS3_ORITB
Sequence: MGQKVNPCIFRTGPNLPRNWESVLYAKNNYSDFLLKILKIRKIINTEYSFAQITKILIEWPSSKNIVVNIYAKKIGVIIGKSGGDIEKLKQNIAKITSADVSINIREVKKPELEEAFIAQTIAQQLERRQSFKKVMKKAIHASMKQGAKGIKIICSGRLGGVEIARSESYKEGRVPLQTIRADIRYAFAEAITTYGVIGVKVWVYRCDVNQSRINEVK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CAJ1_YEAST
Sequence: MVKETEYYDILGIKPEATPTEIKKAYRRKAMETHPDKHPDDPDAQAKFQAVGEAYQVLSDPGLRSKYDQFGKEDAVPQQGFEDASEYFTAIFGGDGFKDWIGEFSLFKELNEATEMFGKEDEEGTAATETEKADESTDGGMVKHDTNKAESLKKDKLSKEQREKLMEMEKKRREDMMKQVDELAEKLNEKISRYLIAVKSNNLEEFTRKLDQEIEDLKLESFGLELLYLLARVYKTKANNFIMSKKTYGISKIFTGTRDNARSVKSAYNLLSTGLEAQKAMEKMSEVNTDELDQYERAKFESTMAGKALGVMWAMSKFELERKLKDVCNKILNDKKVPSKERIAKAKAMLFIAHKFASARRSPEEAEEARVFEELILGEQEKEHKKHTVAR
What are the official names of this protein?
Protein CAJ1.
Protein: SYH_LACLA
Sequence: MKLQKPKGTADLLPAETAKWQYIEEIARGVFNDYNFKEIRTPMFESYELFSRATGETSDIVTKEMYDFEDKGGRHIALRPEGTASAVRAYIENKLYAPEVVKPVKLWYDAPMFRYERPQSGRLRQFHQFGVECLGVKNPAVDVEIIAMADTLFRQLGITGLKLALNTLGDMESRMAYRQALIDYLTPFENQLSEDSRRRLNENPLRVLDSKEAEDIAIVKNAPAILDYLNEASKAYFEEVKALLEALHIEYTIDPNMVRGLDYYNDTIFEFIVDFDGKDLTVCGGGRYDGLVEYFDGPATPAFGFGLGIERLLMIAQKQEINFIPEETLDVYIAVMGEKANLEATKLAESLREQAFKVERDFSNRKLGAQFKTAEKLGAELIITLGEDEIRTGQIKVKHNQTRKQVETTLKAVHESFAPIFEEIYADEEL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSW_ECOLI
Sequence: MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQAFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRLENQEKRAQQEEHHEH
What is the function of this protein?
Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Sulfate transport system permease protein CysW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6045_SACEN
Sequence: MSRTAIFGTLSDDDTKGRRHALGVEGERLAARFLEEHGITVLERNWRCDRGELDIVATDGETVIFCEVKARSGVDYGAPLNAVSPHKVRHLRALARTWLSERNLTGCTARFDVVSVLWPPGRPARIEHLEGAF
What are the official names of this protein?
UPF0102 protein SACE_6045.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TRPA_BURMS
Sequence: MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALAKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLKGVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLEQAVPERAAAELAGFVAELRAAIDGAAKPAA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: 5HT2A_RAT
Sequence: MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores.  Affects neural activity, perception, cognition and mood.  Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.  Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
What are the official names of this protein?
5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Cell projection, dendrite. Presynapse.
Protein: GREA_META1
Sequence: MPNKEEKIYLTADSFKQYQERLQYLQEVLRPQVIEEIKEARNQGDLSENAEYDAARDKQATIENEITEIQHILDNYEIIKTQTNRQVSVVRIGSNVSVVSLKDDTVINFQIVGALDTDPFNGKISNTSPLAKAVIGRKAGEVVEVEAPNKYQVKIVHVG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: BURP6_ORYSJ
Sequence: MPGAIRDLINPVSSAASASKEDTVNNVFFLEKDLFPGSKMTLHFTRATAGAALLPRGRADSVPFASEKLPEILSQLSVPAGSPAADAMRSTLAECEAAPQAGEAKRCATSLESMVEFAASSLGTRDVHAVSTEVDRAGPTPRQAYRVEAVRPVPVSGGDMVACHGMAYAYAVFGCHTTTAAAYTVTLAGADGTKAEALAACHTDAAPRVAEAYKRLGVAPGSVPVCHFLPQDDMLWVRN
What are the official names of this protein?
BURP domain-containing protein 6, OsBURP06.
Protein: NO12_MEDTR
Sequence: MASFSLSILVFFFSALVLVPQGFAEYYLYPAYRPPQTKPPVNKPSHKEPPVNKPPHKEPPVHKPPHKDPPVNKPPQKESPVHKPPRKESPTHRHPPAEDNIHF
What is the function of this protein?
Involved in the infection process during the plant-rhizobium interaction.
What are the official names of this protein?
Early nodulin-12, N-12.
What is the protein family that this protein belongs to?
Belongs to the plant proline-rich protein superfamily. ENOD12 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: DMAC1_HUMAN
Sequence: MGSRLSQPFESYITAPPGTAAAPAKPAPPATPGAPTSPAEHRLLKTCWSCRVLSGLGLMGAGGYVYWVARKPMKMGYPPSPWTITQMVIGLSENQGIATWGIVVMADPKGKAYRVV
What is the function of this protein?
Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Involved in the assembly of the distal region of complex I.
What are the official names of this protein?
Distal membrane-arm assembly complex protein 1, Transmembrane protein 261.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL2_XYLF2
Sequence: MPLIKFKPTSPGRRSAARVVTPNIHKGSPHAALLESQSKTGGRNHHGRITVRHIGGGCKQRYRVIDFKRDKEAIPARVERIEYDPNRTAHIALLCYIDGERCYIIAPKGLKEGDKIISGPNVPIKLGNSLPLRNIPVGTTVHAVELKPRKGAQMARSAGSSVQLVAREGVYATLRLRSGEMRRVLAECRATIGEVGNEEHNLRKLGKAGAKRWLGVRPTVRGAAMNPVDHPHGGGEAKSGQGNPHPVTPWGVPTKGYKTRKNKRTQQFIIRGRRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KCY_METJA
Sequence: MIITIGGLPGTGTTTIAKMIAEKYNLRHVCAGFIFREMAKEMGMDLQEFSKYAEQHKEIDEEIDRRQVEIAKQGNVVLEGRLAAWMLLKNGIKPDLTIWFKAPLEVRAERISKRENIDKDVALKKMIEREASEKKRYKEIYNIDLDDLSIYDLVIDTSKWDVEGVFNIVSSAIDNLKK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.