PharMolix/UniProtQA huggingface dataset:
Protein: FEX2_YEAST
Sequence: MIFNPVISNHKLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLNAYTWMKDHQVLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTKLPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENAGDVDTQEMEKNILEFKFKTPAPFFKKFFDVVDKLAYALAFPLIILFVVLCAYYENYSRGKWTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTDIPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIGISYCLLVITLGSYAWTRGLTNPIC
What is the function of this protein?
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
What are the official names of this protein?
Fluoride export protein 2.
What is the protein family that this protein belongs to?
Belongs to the fluoride exporter Fluc/FEX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIBC_ECOLX
Sequence: MSKKFTMTLLSSSLAGLLVMSGGVSAQEEKYTVPYAIGEGKWGNTYEVVKTGGNGNFRYEVKEKNGKKRSLFTFDSKGDVIINGSGITYTIHDGALNDFAQTAEKKKNGQSQSHRMTDSVVRDVYNKVYSLQRTKITGFSVEDGENGKVSLGSDAKASGEFSVAVGTGARADKKFATAVGSWAAADGKQSTALGVGAYAYANASTAAGTAAYVDGSAIYGTAIGNYAKVDENATEGTALGAKATVTNKNSVALGANSVTTRDNEVYIGYKTGTESDKTYGTRVLGGLSDGTRNSDAATVGQLNRKVGGVYDDVKARITVESEKQKKYTDQKTSEVNEKVEARTTVGVDSDGKLTRAEGATKTIAVNDGLVALSGRTDRIDYAVGAIDGRVTRNTQSIEKNSKAIAANTRTLQQHSARLDSQQRQINENHKEMKRAAAQSAALTGLFQPYSVGKFNATAAVGGYSDQQALAVGVGYRFNEQTAAKAGVAFSDGDASWNVGVNFEF
What is the function of this protein?
Binds (in a non-immune fashion) to the Fc portion of human IgG and less well to IgA; binding occurs on the cell surface.  Confers the ability to survive exposure to human serum exposure (PubMed:10722621).  Binds to the Fc portion of human IgG and IgA and to whole mouse antibodies also via Fc (PubMed:19303642).
What are the official names of this protein?
Immunoglobulin-binding protein EibC, Trimeric autotransporter adhesin EibC, TAA EibC, Type 5 secretion system autotransporter EibC.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family. Eib subfamily.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane; Multi-pass membrane protein. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: NU4LM_SQUAC
Sequence: MSPVYFSFSSAFILGLMGLAFNRSHLLSALLCLEGMMLSLFIAIALWSMTLNSTSCSITPMILLTFSACEASAGLALLVAATRTHGSDHLQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SAC31_MOUSE
Sequence: MGRFKGENRSQARWIMGGVSKGRGSGKSRKPRQAAFGQTGARVCPSSPQQDAVPRFRWPGDAECASSTHTPTMSGCKLPMGLCPDMCPAAERARRERERRLHRLEVEPGGRGNAPRADPKRTVKEYSRPAAGKPRPPPSLLRPPPVLLATVRYLAGEVAGRGDVSCAEVASFVADRLRAVRLDLSLQGVDDADAATVLEAALATLLAVVARVRPEETRGAADPVLLQTQVQEGFGSLRRCYARGKGPYPRQAAFQGLFLLYNLGSVEALQEVLQLPAALRACPPLQAALAVDAAFREDNHARLFRLLRTLPYLQSCAVQEHIGYARRKALARLSRALSTPKGQTLPLDFIEHFLALDGLQEARDLCQAHGLTLDKDRVVFLRGQYSEEGLPPPGAYHILVGNKLQGHTLEDVVMAEEGDIHRPGSAA
What is the function of this protein?
Involved in centrosome duplication and mitotic progression.
What are the official names of this protein?
SAC3 domain-containing protein 1, SAC3 homology domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SAC3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes on centrosomes in interphase cells and at spindles in mitosis.
Protein: SLYX_SALTI
Sequence: MQDITMEARLAELESRLAFQEITIEELNLTVTAHEMEMAKLRNHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: MFD_BORBU
Sequence: MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYEGFFKAFLIKKIKEYSKTGKIILIVKDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIYITVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVKGEIIDIYPFGEQNPIRIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIKSVEYKKILEELDFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNFEKEIEKIHQEYEKLYKEAEEAGKNIIDPKRILLNYKTFNLKSDVLFSKIKSLKSKETIEFKIESERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLIIEKEKIAIILESNIFNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKRIKTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANAKKRIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDETPDQIRAIKEIKEDMMSFKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPTTILAEQHFNTFKKRFKNFPIKIEVLSRFIKNNAESRILKELKSGKIDIIIGTHKILSKKFTCKNLGLIIIDEEQRFGVKEKEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQNRVKIEAYLESFSELLIKHAIESELSRDGQVFLVNHNIEELYYLKTLIERLTPYARIAIIHGKLTGEEIENIMHNFIKKAYQILLATTIIENGIDIPNANTIIINNANKFGLAQLYQLKGRVGRGSQKAYAYFLYQDSEKLNERSIERLRAITEFSELGAGFKIAMKDMEIRGVGNLLGREQHGEIESIGLDYYLTMLNKAIEKKMGKISSDEEEVDIKINYSGFIPENYAKNEQDKILIYKKIFKIQTEEESKKIRSELHNDFGPIPEEINSLLMLAELKILAKDLNITKLKEKNRALEIEYKNIESIPMEKIIEILQKHPNLLILNPSYQKSIFLSFKNIEKSEKINYIYKNINLLKTST
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM147_XENLA
Sequence: MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWRCVQAGATYLCVQLCKMLFLATFFPTWEGAAGAYDFIGEFMKATVDLADLLGLHLVMSRNAGKGEYKIMVAAMGWATAELVMSRCLPLWVGARGIEFDWKYIQMSIDSNISLVHYMAVAALVWMWTRYDLPTHYRLPVTVLLGLSMYKAFLMDCFVHMFIMGSWTALLLKAVITGVLSLSCLTLFVSLVHGN
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions.
What are the official names of this protein?
BOS complex subunit TMEM147, Transmembrane protein 147.
What is the protein family that this protein belongs to?
Belongs to the TMEM147 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ACCD_HISS2
Sequence: MSWIDRIFSKNTTSNSKKSNVPEGVWTKCTSCEQVLYRDELKRHLEVCPKCGHHMRIDARERLVALLDKDSIVEIAADLEPKDILKFRDLKKYKDRLSAAQKETGEKDALITVSATLYGMPIVVAALNFSFMGGSMGSVVGSKFVQAAEKAIELHCPLVCFSASGGARMQEALFSLMQMAKTSAVLAKMKEKGVPFISVLTDPTLGGVSASFAMLGDINIAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEHGAIDMIVKRSEMRETLANLLSKLMNMPSPFVEPELIQEKSDDV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMC6_SCHPO
Sequence: MRRCGIYVYPHRERDILCVKIWTIHLGSWGNPMPNRACVQKVLPVTKQISSDGSVQIDTVRAVLPEFQFPSHPQIGDCLSWIETFFSRSLVGFYDQGYTPGEESCTNSTIKGMSGKPTSIISNIYTTTGPAKVSNDYAVRDPGVAVDHFDQYGPLKEGRSLNSAKISTQWSGSATLKSSNRSIFNIGLGYINTFLGVSNVRGFSTGSGRSKNVLNKLDDLSKRSKNYPNLVIDRNLYKDFLLNRDMFLIAYNKLKSNPGMMTHGLKPDTLDGMSIDVIDKIIQSLKSEEFNFTPGRRILIDKASGGKRPLTIGSPRDKLVQEILRIVLEAIYEPLFNTASHGFRPGRSCHSALRSIFTNFKGCTWWIEGDIKACFDSIPHDKLIALLSSKIKDQRFIQLIRKALNAGYLTENRYKYDIVGTPQGSIVSPILANIYLHQLDEFIENLKSEFDYKGPIARKRTSESRHLHYLMAKAKRENADSKTIRKIAIEMRNVPNKIHGIQSNKLMYVRYADDWIVAVNGSYTQTKEILAKITCFCSSIGLTVSPTKTKITNSYTDKILFLGTNISHSKNVTFSRHFGILQRNSGFILLSAPMDRIAKKLRETGLMLNHKGRSVIRWLPLDVRQIIGLANSIIRGYDNYYSFVHNRGRFATYVYFIIKDCVLRTLAHKLSLGTRMKVIKKFGPDLSIYDYNSRDENNKPKLITQLFKPSWKVNVWGFKSDKVKLNIRTLYASHLSMANLENLQCAACQSTYKVEMHHVRQMKNLKPIKGTLDYLMAKANRKQIPLCRSCHMKLHANKLTLNEDKKV
What are the official names of this protein?
Uncharacterized 91 kDa protein in cob intron.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMN_PSEPW
Sequence: MTTSTGKINLLGLTQPEMEQFFDSIGEKRFRAGQVMKWIHHFGVDDFAAMTNVGKALREKLEAVAEIRPPEVVSEDISADGTRKWVIRVASGSCVETVYIPTDDRGTLCVSSQAGCALDCSFCSTGKQGFNSNLTAAEVIGQVWLANKSFGTVPAKIDRAITNVVMMGMGEPLLNFDNVIAAMKIMMDDLGYGISKRRVTLSTSGVVPMIDELAKHIDVSLALSLHAPNDELRNQLVPINKKYPLKMLLESCMGYMATLGGKRVLTVEYTLLKDVNDQPEHAAQMIELLRDVPCKINLIPFNPFPHSGYERPSNNAIRRFQDLLHHGGFNVTTRTTRGDDIDAACGQLVGQVNDRTRRSERYIAVRQLSADAELQDSAVRH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_ORYSA
Sequence: MLFATLEHILTHISFSTISIVITIHLITLLVRELGGLRDSSEKGMIATFFCITGFLVSRWASSGHFPLSNLYESLIFLSWALYILHMIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAALLMIRFRKNLDFFSKKKKNVLSKTFFFNEIEYFYAKRSALKSTFFPLFPNYYKYQLIERLDSWSYRVISLGFTLLTIGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNPNWKGTKSAFVASIGFLIIWICYFGINLLGIGLHSYGSFTLPI
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PDAD1_ARCFU
Sequence: MLPRKVFFTKGVGRHTDPLVSFELALRDAGIEKFNLVTVSSIYPPYCEIVEAEKGLSELFPGQIVFCVMSRMTSNEQGKRIFASVGAAIPPDPSLNGYLTEYHGYCNGEDAGRHAEESAAYMLKTAFEIEPARTFNITVEADVEDCTTVVAAAVFVI
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase 1, PvlArgDC 1.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: SECY_STAES
Sequence: MFQTFVRFFTTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPEAFNHPQGSQGATELLNTFGGGALKRFSIFAMGIMPYITASIVMQLLQMDIVPKFTEWAKQGEMGRRKINNVTRYFAIILAFIQSIGMAFQFNNYLKGQLIIEKSVMSYLLIAVVLTAGTAFLIWLGDQITQFGVGNGISLIIFAGILSTLPSSLEQFAQSVFVGQDDTSLAWLKILGLIVALILLTVGAIFVLEAKRKIPIQYAKKQSAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFFPKAEWAQNIADTANPSSNIGMIIYVVLIIAFAYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAAIAILPIIATKFMGLPQSIQIGGTSLLIVIGVAIETMKTLEAQVTQKEYKGFGGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP4B_RABIT
Sequence: MAALQEKKSCSQRMEEFRHYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGEKGLEIHYNISDNRTWTSLTHTLRSFLAGYSPAAQVDNINCTSKTYFFQESFGAPNHTKFSCKFTADMLENCSGLTDPSFGFKEGKPCFIIKMNRIVRFLPSNSTPPRVDCTFLDMPHQALTPLQVEYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNVPTNTEVVVLCKILADHVTFDNPHDPYEGKVEFKLKIQK
What is the function of this protein?
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells (PubMed:7485470, PubMed:10722662, PubMed:11909858).  Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (PubMed:7485470, PubMed:10722662, PubMed:11909858).  Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2) (By similarity).  Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (By similarity).
What are the official names of this protein?
Potassium-transporting ATPase subunit beta, Gastric H(+)/K(+) ATPase subunit beta, Proton pump beta chain.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Note=Localized in the apical canalicular membrane of parietal cells.
Protein: YJJY_ECOLI
Sequence: MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILTAT
What are the official names of this protein?
Uncharacterized protein YjjY.
Protein: RS6_BRUC2
Sequence: MALYEHVLLARQDISQQQVDALVEQFKGVLEANGGKFGKVENWGLRPLTYRIKKNRKAYYTLVNIDAPAAAVAEMERQMRINEDVLRFLTVRVEEHEEGQSAMLTRRDDRRERDGDDRPRRREGGFDRGDRGDRGPRRPRDTEAGEGA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PTOCB_ECOLI
Sequence: MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGFIGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in maltose transport.  MalX can also recognize and transport glucose even though this sugar may not represent the natural substrate of the system.
What are the official names of this protein?
PTS system maltose-specific EIICB component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y445_BACCZ
Sequence: MSIKYSNKINKIRTFALSLVFIGLFIAYLGVFFRENIIIMTTFMMVGFLAVIASTVVYFWIGMLSTKTVQIICPSCDKPTKMLGRVDACMHCNQPLTMDRNLEGKEFDEKYNKKSYKA
What are the official names of this protein?
UPF0295 protein BCE33L0445.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSJ_ECO57
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGVVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQEEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: VE6_HPV47
Sequence: MAQKALEQTTVKEEKLELPTTIRGLAQLLDIPLVDCLLPCNFCGRFLDYLEVCEFDYKKLTLIWKDYSVYACCRLCCSATATYEFNVFYQQTVLGRDIELATGLSIFEIDIRCHTCLSFLDIIEKLDSCGRGLPFHKVRNAWKGVCRQCKHFYNDW
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: PUR5_YERPE
Sequence: MTNKTSLSYKDAGVDIDAGNDLVDRIKGVVKQTRRPEVMGGLGGFGALCALPQKYREPILVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYFATGKLDVDTAASVITGIAEGCKQSGCALVGGETAEMPGMYHGDDYDVAGFCVGVVEKSEIIDGSKVTPGDVLVALGASGPHSNGYSLVRKILDVSNTNPEQTSLEGKSLADHLLEPTKIYVKSILSLIEQLDIHAIAHLTGGGFWENIPRVLPQGMQAVIDEASWQWPAVFSWLQQAGNVSRHEMYRTFNCGVGMVVALPAELADKAVELLTASGEKAWKIGVIAAATEGAEQVIINP
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURG_MOUSE
Sequence: MERARRRGGGGSGGGRGRGGKNVGGPGLSKSRLYPQAQHSHYPHYSASATPNQSGGTSEIQELASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRGRQDNIRKSKLTLSLSVAAELKDCLGDFIEHYAHLGLKGHRQEHGQSKEQVSRRRQKHSAPSPPVSVGSEEHPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRGTGMIGYFGHSLGQDQTIVLPAQGMIEFRDALVQLIEDYGEGDIEERRCGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRPPYRNTITVPFKAWTRFGENFIKYEEEMRKICNSHKEKRMDGRRASGEEQECLD
What are the official names of this protein?
Purine-rich element-binding protein gamma.
What is the protein family that this protein belongs to?
Belongs to the PUR DNA-binding protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK_CORGB
Sequence: MTERTLILIKPDGVTNGHVGEIIARIERKGLKLAALDLRVADRETAEKHYEEHADKPFFGELVEFITSAPLIAGIVEGERAIDAWRQLAGGTDPVAKATPGTIRGDFALTVGENVVHGSDSPESAEREISIWFPNL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP_LACSA
Sequence: MARMAMMILCVVLTCMVVATPYTEAAISCGQVTANLAGCLNYLRNGGAVPPACCNGVRSLNSAAKSTPDRKTACNCLKNASKSVSGIKAANAAGLPGKCGVNIPYQISPNTDCSKVQ
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein Lac s 1, nsLTP Lac s 1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: NQRE_SACD2
Sequence: MEALLSIFVESVFVKNMALAYFLGMCTFLAISKKIDAAIGLGIAVVVVLTITVPVNNLMFNYLLADGALAWAGLEGVDLSFLGLICYIGVIAAIVQIMEMVLDKYFPALYGALGVFLPLITVNCAILGAALLMVQREYTFSESVVFGVGSGVGWAFAIVALAGIREKLKYSDVPEGLRGLGITFITVGLMSLGFMSFGGIAL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ANG1_EMENI
Sequence: MQLLALTLALCASIAALPTQQTPLPLEDPIKSPFPIHHSCNATEQRQLATALQETVTLAEHAKDHILRWGNESAIYRKYFGDRPSLTAIGAYDIIVNGNPDNILFRCDNPDGNCALEGWGGHWRGENASDETVICELSYTTRRSLSTMCSQGYTISEWETNTFWAGDLLHRLYHMPAIGQGLVEHYADGYEGVLELAEGNRTEAVHDSETLQYFALEVYAYDVAVPGIGCVGGEEENDGQGEEQTEEPAQDDQQDEAAEEEIPENCHTHEGGELHCT
What are the official names of this protein?
Antigen 1, ASPND1.
What is the protein family that this protein belongs to?
Belongs to the ZPS1 family.
Protein: NMO_STAA2
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKIIEEQQFKCHIDTIIKKQVPVCCFTFGIPNESIIERLKEANIKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: CLPP1_BACHK
Sequence: MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDTMNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQPIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.