PharMolix/UniProtQA huggingface dataset:
Protein: PA2H3_BOTPI
Sequence: DLWQFGQMILKETGKLPFPYYTYGGCYCGVGGRRGLGTKDDRCCYVHDCCYKKLTGCPKTDDRYSYSWLDLTIVCGEDDPCKELCECDKAIAVCFRENLGTYNKKYRYHLKPCKKADKPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity.  Shows high myotoxin activities (PubMed:10395455).  Also has anticoagulant activity (PubMed:10395455).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog piratoxin-3, svPLA2 homolog, MP-III 4R, Piratoxin-III, PrTX-III.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EZH2A_XENLA
Sequence: MGQTGKKSEKGPVCWRKRVKSEYMALRQLKKFRRADEVKSMFNTNRQKIMERTEILNQEWKQRRIQPVHIMTTVSSLRGTRECSVTSDLDFPKQVIPLKTLTAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALAQYSDYEDDEDGDDNQDDEQDDTAKDQDDNMEDKETQPLRKFPSDKIFEAISSMFPDKGTSEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRPCFKYDCFLHPFHATPNTYKRKNNEAANDGKPCGPHCYQLLEGAREFAAALTAERIKTPPKRPSGRRRGRLPNNTSRPSTPTVNVSEAKDTDSDREAGTETGGESNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASLFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIISPVIAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFINDTVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
What is the function of this protein?
Polycomb group (PcG) protein (By similarity).  Catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).  May repress transcription of the egr2 and en2 genes.  May regulate the circadian clock via histone methylation at the promoter of the circadian genes (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase EZH2, Enhancer of zeste homolog 2-A.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CRCB_CROS8
Sequence: MLKIMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLVTTGLCGGLTTFSTFSAEVVFLLQEGRIGWAGLNVALNLFGSFMMTALAFWLFSSLSVR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CODY_LACLM
Sequence: MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLGMKGTYLKVLNTGLFDKLAGRNF
What is the function of this protein?
Targets include genes involved in amino acid transport and metabolism, but also several genes belonging to other functional categories (PubMed:16040604).  Among others, they include major components of the L. lactis proteolytic system such as intracellular peptidases (PepO1, PepN and PepC), the dipeptide transport system (dpp), the oligopeptide transport system (Opp) and the ilv-ald operon for BCAA biosynthesis (PubMed:11401725, PubMed:16040604).  Binds to a 15-bp cis-sequence, the CodY-box (PubMed:16040604).  Multiple copies of the CodY-box are present in the intergenic regions of some transcriptional units (PubMed:16040604).
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODBB_THET8
Sequence: MALMTMVQALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAIVGAALGMAAHGLRPVAEIQFADYIFPGFDQLVSQVAKLRYRSGGQFTAPLVVRMPSGGGVRGGHHHSQSPEAHFVHTAGLKVVAVSTPYDAKGLLKAAIRDEDPVVFLEPKRLYRSVKEEVPEEDYTLPIGKAALRREGKDLTLIGYGTVMPEVLQAAAELAKAGVSAEVLDLRTLMPWDYEAVMNSVAKTGRVVLVSDAPRHASFVSEVAATIAEDLLDMLLAPPIRVTGFDTPYPYAQDKLYLPTVTRILNAAKRALDY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDH E1-beta.
Protein: MURI_PSEA7
Sequence: MAAESAPVGVFDSGVGGLSVLREIRARLPAESLLYVADNAHVPYGEKSAEYIRERCERIGDFLLERGAKALVLACNTATAAAAAELRERYPQVPLVAMEPAVKPAAAATRNGRVGVLATTGTLKSARFAALLDRFASDVQVFTQPCPGLVERIEAGDLHGARTRALLERLLGPILEQGCDTLILGCTHYPFVKPLLAELIPADIAVIDTGAAVARQLERVLSTRALLASGQAAAPRFWTSALPEEMERILPILWGSQESVGKLDV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: URE2_CHESB
Sequence: MIPGEVIPKAGEIELNAGAPQVVLEVSNTGDRPIQVGSHYHFYETNGALSFDREKARGMRLDIAAGTAVRFEPGQAREVRLVPLSGARKVFGFQQKIMGDL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_ARATH
Sequence: MRIVGLTGGIASGKSTVSNLFKASGIPVVDADVVARDVLKKGSGGWKRVVAAFGEEILLPSGEVDRPKLGQIVFSSDSKRQLLNKLMAPYISSGIFWEILKQWASGAKVIVVDIPLLFEVKMDKWTKPIVVVWVSQETQLKRLMERDGLSEEDARNRVMAQMPLDSKRSKADVVIDNNGSLDDLHQQFEKVLIEIRRPLTWIEFWRSRQGAFSVLGSVILGLSVCKQLKIGS
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, AtCoaE, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SHE2_YEAS7
Sequence: MSKDKDIKVTPGTCELIEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLSALDEEFDVVATKWHDKFGKLKN
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Recruits the MYO4-SHE3 complex to the ASH1 mRNA.  Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner. The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA.
Protein: GSA1_BACMK
Sequence: MNFTKSEALHKEALEHIVGGVNSPSRSFKAVGGGSPVAMERGKGAYFWDVDGNKYIDYLAAYGPIITGHAHPHITKAITTAAENGVLYGTPTALEVKFAKMLKEAMPALDKVRFVNSGTESVMTTIRVARAYTGRTKIMKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPQSIAQEVITVPFNNVETLKEALDKWGHEVAAILVEPIVGNFGIVEPKPGFLEKVNELVHEAGALVIYDEVITAFRFMYGGAQDLLGVTPDLTALGKVIGGGLPIGAYGGKKEIMEQVAPLGPAYQAGTMAGNPASMASGIACLEVLQQKGVYEKLDELGAMLEKGILEQATKHNIDITVNRLKGALTVYFTTNTIEDYDAAKNTDGEMFGRFFKLMLQEGINLAPSKYEAWFLTTEHTKEDIEYTIEAVGRAFAALADNK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM5B_HUMAN
Sequence: MPCGFSPSPVAHHLVPGPPDTPAQQLRCGWTVGGWLLSLVRGLLPCLPPGARTAEGPIMVLAGPLAVSLLLPSLTLLVSHLSSSQDVSSEPSSEQQLCALSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVAGRKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCSTLEDSSNMSLWTQNITACPVRNVTRDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIFWASWGSWSKCSSNCGGGMQSRRRACENGNSCLGCGVEFKTCNPEGCPEVRRNTPWTPWLPVNVTQGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPADGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACPEGWSPWSEWSKCTDDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYSEIPVILPASSMEEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYKGGGTPKNEKYTPMEFKTLNKNNLIPDDRANFYPLQQTNVYTTTYYPSPLNKHSFRPEASPGQRCFPNS
What is the function of this protein?
May act as positive axonal guidance cues.
What are the official names of this protein?
Semaphorin-5B.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: RS8_RICRS
Sequence: MSMTDNVADMLTRIRNAYKSKLISVSFPSSKIKTSILDVLQKEGYIKDYITTQKNNISYTEVALKYSVNGDASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYILSTPYGVMSDREAHIKNVGGEVICKVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CA11_CONPL
Sequence: MGMRMMFTVFLLVVLATTVVSFTSDRTSDGRNAAFNAFDLIALTARQNCCNVPGCWAKYKHLCGRKR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Pu1.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CO1A1_MYLDA
Sequence: SAGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGASGPAGARGNDGAAGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGEPGAPGSKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGSNGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVSPPGPPGPTGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPVGPPGLAGPPGESGREGSPGAEGSPGRDGSPGPKGDRGESGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: PETL_HORVU
Sequence: MLTLTSYFGFLLAALTITPALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EFR3_ASPOR
Sequence: MEGVRQKCRPKHQVLVLKCYPQYQKGVQVVKPNSSELSYLLYYVSTRRSKLTKVGAFLEKRAARDVWRRKIGNVQVTLQILSALIEKVPRDLPIYARSVMTVLETVVRSQDISMVEDSIETFETFCRHQDMAALSAEQDFATQYREVVRSYAGFAEGDPSTQSKLAAGPPLTVRWKTAGLRAIKGVVSSEAGLAADGGDSIRVILPVILENLYSPEDNLVGSLELKLLEADKNESETAHRRRVSTATVETVDAVEGDASLAAQNTADMDRKAEMDMRLLALRCLEQIVVNGSSRGQIRVTTQVVLDFILRKSRVTGNGLGHNHKDSWATSLIELIAKWCPVQVRFIILVAAMDILHDIPPTEESLDESFAITYLIDRLLKSPVNMIGLSVIDVLLGLLRHMSFLISPSRAGKSTPDEKQNGHSNALELSVKRTEVLSLLQDCIGNLTTHIYYGEQVVDMVRTILTRFRPSRGNEQAITSSPTQSDVLGGASAMISSGEDGLIAFSLPNAKITALRAIKNILLVANTKRPGFTVTTESRHQVGLYVWEGTQWLLSEPDRDVRYAYVDAFLTWLNLETSTDDLKVKERTGRPASQPAKNDLSDPTERPGKRTASMSGNQREKVILIAQSNFLRLLHLTIFDLATDHPTSVSEITLLHLLLVSLVKHLGVNAVRFGLPMVLKLQDNMTTGDGQSFPALVNIGSLVYGYLWALSEKFDLDTSRIGNGIQSEVQKRQQLGVWLETIRLPPVNLDKIIHNSNVQASGRGAQDVSLLIPFDGGEELIQRIEASYGSFITLLTHSPPSSPGSVGSPPRSITAPVLPHVSASAATPKANVLPPAVREQMLSPWSREACLAAAENERAEAKSLSRSRTGTLVMRNHVHQNGTSSPSASSNASVPQSAYASAAGLQNAQRTSVPNSSGSQLISTSRESPVHVNELRRVLSVNEEGKARRMSPLRGRLDGSNRSVISSSSDSMVSGYSLSEFDDGASVKPQSTRGGRISLDGEETPKASALSFMADTNDIPPVPPIPPSISIQGGLTDGRQRSVSASRPSTAPGPRRPSVTNGKAGTPSTSPGRSLSRDKSRSSTGLAAAATDGVEPNAEKIDSARLDVQKLLDGFLSPADAETRGSRRKARSNTGRRGVSGGLGRPPY
What are the official names of this protein?
Protein efr3.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
Protein: NHAP2_SHESA
Sequence: MDADSINSFFLIGALLAAVSVLLSPVSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGVMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVDAELSVSFMLISFIKQFGLGIFLGLGGGWLLWKLVNLSKLAEGLYSILVLSGGLMIYAASNKLGGSGILSIYLVGLFLGNKPTRGRHSILNVLDGMTWVSQIGMFLVLGLLLTPSDLLDIWLPGLALAFGMILFARPLAVWLSLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPISRSGVEIYPSSEWEVFVYHLSENKWCIGEPLKRLSMPDGTRIAAVFRHNTLLHPSGSTCLEAGDILCVLGQEKSLEALSNLFSQAPETKEVPRFFGDFFIDTEVKLLDLAPIYGLELDEATGDMTVADLVAAELGSHPVLGDQFLWQSLHWVVAGLNEGKVTNVGIRLPAEA
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRTB_ACIGU
Sequence: ARRRRRSSRPQRRRRRRRHGRRRRGRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-B, Sturine-B.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMM_BACCR
Sequence: MGKYFGTDGVRGVANKELTPELAFKIGRFGGYVLTKDTDRPKVIIGRDTRVSGHMLEGALVAGLLSTGAEVMRLGVISTPGVAYLTKALDAQAGVMISASHNPVQDNGIKFFGSDGFKLTDEQEAEIEALLDKEVDELPRPTGTNLGQVSDYFEGGQKYLQYIKQTVEEDFSGLHIALDCAHGATSSLAPYLFADLEADISTMGTSPNGMNINEGVGSTHPEGLAELVKEKGADIGLAFDGDGDRLIAVDEKGNIVDGDQIMFICAKYMKETGQLKHNTVVSTVMSNLGFYKALEANNITSDKTAVGDRYVMEEMKRGGYNLGGEQSGHIILLDYITTGDGMLSALQLVNIMKMTKKPLSELAGEMTKFPQLLVNVRVTDKKLALENEKIKEIIRVVEEEMNGDGRILVRPSGTEPLIRVMAEAPTQEVCDAYVHRIVEVVKAEVGAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ADH1_ORYSJ
Sequence: MATAGKVIKCKAAVAWEAAKPLVIEEVEVAPPQAMEVRVKILFTSLCHTDVYFWEAKGQTPVFPRIFGHEAGGIVESVGEGVTDLAPGDHVLPVFTGECKECAHCKSAESNMCDLLRINTDRGVMIGDGKSRFSINGKPIYHFVGTSTFSEYTVMHVGCVAKINPAAPLDKVCVLSCGISTGLGATINVAKPPKGSTVAIFGLGAVGLAAAEGARIAGASRIIGIDLNANRFEEARKFGCTEFVNPKDHDKPVQQVLAEMTNGGVDRSVECTGNINAMIQAFECVHDGWGVAVLVGVPHKDAEFKTHPMNFLNERTLKGTFFGNYKPRTDLPNVVELYMKKELEVEKFITHSVPFSEINTAFDLMHKGEGIRCIIRMEN
What are the official names of this protein?
Alcohol dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAPR_EXIS2
Sequence: MRVPKKERQTELQHTIEQNPFITDEALATHFNVSIQTIRLDRMEMKIPELRERIKHVATERLDDVRTLTENEVIGDMIDLKLDTSAISILEILPEHAFSRNAIARGHILFAQANSLAIALIDDELALTTKANVQFTRSVHVGERVVAKAFVSSHRQDGRSDINVESFVGDECVFIGEFTVYRSSKEESK
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: CHIS_NIACI
Sequence: MHMSNARPSKSRTKFLLAFLCFTLMASLFGATALFGPSKAAAASPDDNFSPETLQFLRNNTGLDGEQWNNIMKLINKPEQDDLNWIKYYGYCEDIEDERGYTIGLFGATTGGSRDTHPDGPDLFKAYDAAKGASNPSADGALKRLGINGKMKGSILEIKDSEKVFCGKIKKLQNDAAWRKAMWETFYNVYIRYSVEQARQRGFTSAVTIGSFVDTALNQGATGGSDTLQGLLARSGSSSNEKTFMKNFHAKRTLVVDTNKYNKPPNGKNRVKQWDTLVDMGKMNLKNVDSEIAQVTDWEMK
What is the function of this protein?
Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
What are the official names of this protein?
Chitosanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 46 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1650_HAEIN
Sequence: MPNERNIQNYHSTYNNIRDWLGYQKAGEEKAKSTIN
What are the official names of this protein?
Uncharacterized protein HI_1650.
Protein: BGAM_LACHE
Sequence: MDYTNNQLHIIYGDATLGVNGKDFQYIFSYERGGLESLKVHGKEWLYRVPTPTFWRATTDNDRGSGFNLKAAQWLGADMFTKCTDIHLKVDRHDFAELPIAPFNNKFSNHEYAKSAEISFTYQTLTTPATNAKIIYNIDDVGHIKVTMRYYGKKGLPPLPVIGIRLIMPTAATGFDYEGLSGETYPDRMAGAKEGKFHIDGLPVTEYLVPQENGMHMQTKKLTINRETTQNNVDRTNEKFSLSIQQAEKPFNFSCLPYTAEELENATHIEELPLVRRTVLVIAGAVRGVGGIDSWGTDVESAYHINPELDHEFSFILN
What are the official names of this protein?
Beta-galactosidase small subunit, Beta-gal small subunit, Lactase small subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial beta-galactosidase small subunit family.
Protein: SYY_CITK8
Sequence: MEILMASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEDTVQEWVDKIRKQVAPFLDFDCGDNSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVTLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIAEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITESLFNGNLSDLSEADFEQLAQDGVPMIEMEKGADLMQALVDSELQPSRGQARKTIASNAVTINGEKQSDPEYFFQDSDILFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC1_STAEQ
Sequence: MHKRLFITLLGFIILLAGCDYSKEENQTGIFYNVFVKSMDGFLHFLGRVFQDNYGFAIISIVLIVRFILLPFMLIQVKNMHMMREKTKVVQPELDAIRDKMKHATSQEERNAANQLLMKKYQSYGINPLKNMLGCLPVLIQMPILMGLYMSLKYPSSHGITEYPHFLWFDLTQPDLIMTIIAAIMYFVQPLVNSIHYPKDQRKTYYFMMVFSPIFITYASLHSAAALGLYWSISAAFLIVQMHFAHSHYKKVALHEAKKLKQKLEQNKDNSELLTEES
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_STRSY
Sequence: MRIDILTLFPEMFAPLEHSIVGKARDKGLLEINYHNFRENAEKARHVDDEPYGGGQGMLLLAQPIFDTMDSIEQTKPRVILLDPAGRTFNQAYAEELAQEEQLIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKEVSHTDDSFSSGLLEYPQYTRPYEYRGMVVPDVLMSGHHENIRKWRLEESLRKTYQRRPDLLENYNFTAEELTIFEKIKAEDTVD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NP03_GAHVM
Sequence: MYKRPGHKHLSISIIMDTNTPSVLTVLASWGWNCASSSPATQCLERSTQGCLREGPSAQGCDYCEPVNVENGPPTTFVKNQDHAKNQEYTHFDTLFMVSSIDELGRRQLTDTIRRDLRHSLAKFTIACTKTSSFSSSYATRKGRKKKGPRTQPSNKSLQMFILCRRAHAKHIRAQLQAVIQARKPRKYYTRAIDGSTHPVVPVFVYEFAAIDTVSLHRDNVIVDSSGS
What are the official names of this protein?
Nuclear phosphoprotein UL3 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL3 family.
What are the subcellular locations of this protein?
Host nucleus.