PharMolix/UniProtQA huggingface dataset:
Protein: IF1_BACFN
Sequence: MAKQSAIEQDGVIVEALSNAMFRVELENGHEITAHISGKMRMHYIKILPGDKVRVEMSPYDLSKGRIVFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_XANCP
Sequence: MNATLRILAWLIAVALVALPVVAVLNGWVGAERWPLARLRVSGDFKRVPAEELRAVVLPYARSGFFAVKLQDAQDAIARLPWVESAQVRKRWPDVLEVHVVEHKPFARWGTDRMLSEQGRLFRTPPLLKDFKLPQLGGPDAKTQEVVALYNESRALFAPTGLDVERLEMDARGSWSLGLSNGVQIVIGRDDARARLQRFARVLPQLTDPQRPIARADLRYTNGFTVERRMENGESGMDKKPKPVPPAAPHALVLNSLRLRTPLLTIPHSPFAIPGFKT
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: FUS_MUMPR
Sequence: MKAFSVTCLGFAVFSSSICVNINILQQIGYIKQQVRQLSYYSQSSSSYIVVKLLPNIQPTDNSCEFKSVTQYNKTLSNLLLPIAENINNIASPSPGSRRHKRFAGIAIGIAALGVATAAQVTAAVSLVQAQTNARAIAAMKNSIQATNRAIFEVKEGTQQLAIAVQAIQDHINTIMNTQLNNMSCQILDNQLATYLGLYLTELTTVFQPQLINPALSPISIQALRSLLGSMTPAVVQATLSTSISAAEILSAGLMEGQIVSVLLDEMQMIVKINIPTIVTQSNALVIDFYSISSFINNQESIIQLPDRILEIGNEQWSYPAKNCKLTRHHIFCQYNEAERLSLESKLCLAGNISACVFSPIAGSYMRRFVALDGTIVANCRSLTCLCKSPSYPIYQPDHHAVTTIDLTTCQTLSLDGLDFSIVSLSNITYAENLTISLSQTINTQPIDISTELSKVNASLQNAVKYIKESNHQLQSVSVNSKIGAIIVAALVLSILSIIISLLFCCWAYIATKEIRRINFKTNHINTISSSVDDLIRY
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: FES1_KLULA
Sequence: MEKLLHWSIANAQGDDEAKARAGQPDPKLLEQLFGGGPDEPTLMKHAMAVISNPEATLENKLVAFDNFEMLIENLDNANNIENMKLWEPLITVLDDPEPELRAFALSVTGTAVQNNDQSQNNFAKYDGALAKVIKLASGRAEDAQVRTKAFYTLSNLIRHNKLIYDQFNQLNGLQIIAPVLKDANASEKLKLRAMALLSTVLTVADMNADFFALLRAYNIIETTLEFLHPECNLYLIDRVLNFFSQLINVGFEFSATELEKLKVGVKNIEPVEAQLNEDDYKTVQYVSK
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_CLOAB
Sequence: MKGIIYLEDGTVFYGTGFGKEGNEFGEIVFNTSMTGYQEILTDPSYAGQIINMTYPLIGNYGVNESVNQSKCVYAKGFIVKNIDENPSNYTSEINIDQMLKNMGVVGVFGVDTRSITKKIRSYGTMKCIISNGELSIEELKKMMDASNIVDDYVNTVSTKEIIHIAGNGNKVAVMDFGIKNDIIENLKERQCDITIFPYDTDYNEILNINPDGIFLSNGPGDPKSIPEAIENVKKLIGKRPMFGICLGHQIIALASGGNTYKLKYGHRGGNHGIYDVQRDKAYITAQNHGYAVDEESVLENGMIITHRNLNDGTVEGMKHKSIPLFSVQFHPEGAPGPTDTTYLFDQFVNL
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: NOT3_SCHPO
Sequence: MSARKLQVEIEKTFKKVTDGIAIFDEVYEKLSASNSVSQKEKLEGDLKTQIKKLQRLRDQIKTWASSNDIKDKKALLENRRLIEAKMEEFKAVEREMKIKAFSKEGLSIASKLDPKEKEKQDTIQWISNAVEELERQAELIEAEAESLKATFKRGKKDLSKLSHLSELESRIERHKWHQDKLELIMRRLENSQISPEAVNDIQEDIMYYVECSQSEDFAEDENLYDELNLDEASASYDAERSGRSSSSSHSPSPSASSSSSSENLLQDKAEAEEKVSADASVQDIAEKESLDADKELATNDQEDDEEENQAETQKDGAISNNENMQSEVQTTNPSASTSAVTNITKPTLIQNPSTPLSVSNSKVASPETPNATHTAPKVEMRYASAAAAAAAALAKESPSHHYIMQQVRPETPNSPRLNSTVIQSKWDSLGHTASPKMQTQPVRSVSQSSATTETNVKPTKEENADVPVSSPDYLKDLVNALNTSKEQHKGAIDKEKLTEALNISCVYVPDATDAAKPQYYIPKDPYPVPHYYPQQPLPLFDSSEMTELVDPDTLFYMFYYRPGTYQQYIAGQELKKQSWRFHKKYTTWFQRHEEPKMITDEFESGSYRYFDFEGDWVQRKKADFRFTYQYLEDDDDWTR
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery (By similarity).
What are the official names of this protein?
General negative regulator of transcription subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CNOT2/3/5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYE_RHOBA
Sequence: MIRTRFAPSPTGYLHIGGVRTALFNWLLAKQAGGQFILRIDDTDAGRNVDAALKPILDGFRWLGMDWDEGPDVGGPHGPYFQSERGDQYRAAAEKLLADGHAYRDFAKPEELQTLREEAQKGGEAFVYDRRWMAEDEATAAKFEAEGRQGVVRLKMPREGQCVIQDLIRGEVVVEWASEQDHVIARADGSPLYHLASVVDDHELKITHVVRAAEHLPNTARQVFIAQSLGYELPIYAHLPYVAEPGGSAKLSKRKLDKYKKNRDFAVLLAHGEKIAERCNMQVDADTFNPVLVDFYREIGFLPDALLNYLLLLGWSLDGETEKFTIAEMIEKFTLDRVNKAPASFDPAKLQSFQGDAFAELSDEKRTELVRPFAVAAGFVADGDADETLKAVLAAAGDRLKMAGDIVDFDYCFVDDYSVDEKAYEKRLAKADGAKELLAKLNETLKAATEFDAANVETTVKSFCESEGIKIGQIIHALRVATTGAASGFGMFDTLAVLGKDKVTARIEKTIAGLS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYX_RHOPA
Sequence: MAGENDLNDRVEALEVRLAYQDETIEALNQTVTAQWKQIDALTRQLAALSERLDQAESSAGAPANERPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: CAE21_RANCI
Sequence: QQDYTGAHMDF
What is the function of this protein?
Hypotensive neuropeptide.
What are the official names of this protein?
Caerulein-2.1/2.1Y4.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_CHRSD
Sequence: MSDYKHTLNLPETDFPMRGMLPKREPGRVSQWQDMNLYQRLRDARAGREVFVLHDGPPYANGSIHIGHAVNKILKDIVVKSKSLAGYDAPYVPGWDCHGLPIEHKVETTHGKHLEADEARGLCREYAGAQIEGQKTDFVRLGVVGDWENPYRTMDFANEAGEIRALAKMVEGGYVFKGLKPVNWCFDCGSALAEAEVEYADKKSDAIDVAFAAAEPEALASAFGLASLDKPAAIVIWTTTPWTIPANQALNVHPDFTYALVDTGELLLVLAEELVESCLTRYGLEGDVVATAAGASLEFITFRHPFYERVAPVYLADYVTVEEGSTGIVHSAPSYGLDDFMTCREHGMSFDDMLNPVQGNGVYRDDLPLFGGQMIWKANPHIVDTLREVNALMAHTPITHSYMHCWRHKTPVIYRATAQWFVGMDREDDQGRTLRQRALDGVEATQFIPAWGKARLHSMIANRPDWCISRQRNWGVPIPFFMHKQTGEWHPRTVELMEDVARRVEAEGIDAWFRLDARELLGDEADQYDKVTDTLDVWFDSGTTHRHVMRGSHPMGHDQGPRADLYLEGSDQHRGWFHSSLLTGCAIDGHAPYKALLTHGFTVDEKGRKMSKSMGNVIAPQQVMDKLGADILRLWVASTDYSGEMAVSDEILKRTADVYRRIRNTSRFLLANLNGFAPERDAVAFEDMLALDQWVVDRAAQLQARIQGAYAEYRFRDVYQQVHDFCAHELGGFYLDVIKDRQYTTQADSRSRRSCQTALYHVVEALVRWVAPILSFTAEEIYEVIPGTRGDSVLLEEYYPHLATLEANAAMGREFWSRVLTVKQAVNKCLEDARNAKVVRNSLAAEVTLYADDSLRETLTQLGEELRFVLLTSEVHLASLEDAGSAQAEASELEGLKVAVVSSPHAKCERCWHHRADVGTHAADPNLCGRCLSNLPEGPGETRRYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC187_HUMAN
Sequence: MPTLVVGTPPTCLGDTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAALRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSCSSGGHDVCVSWKERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSASRLHKASTLMLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGPPPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAYSDQQVSGNTPSLASFDQPATIQTAMAILQDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGCCRDPNAQSSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLEASGSLESPVLEWSKVTSGMVLGGQEAPGSFCLCLNRAWNHAETLDPPGMGGPQDGRDAPVLLSASPSLGSLELQDLTTRYLPRGMCIYLDPKEAEHLGTSSSLHLRHKQAQLQALETTAKVLKQRVDSLTAKLQGAEALDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWGRGAPGEWVSMQPQPLLPPTYFLDGETLSWGPSWEQQQSVSPRAHCESKPRGFPEEGHVDVKPDKRLQRGVAPFQALSPSAGSSYAGPATLHPIWGSLGLEETPSVGGADSVAPCTPRSCGKGDPADRPWAGWSGGRGIHREHLPLPSTRAWPYGVEKSFSTWRASTPRY
What are the official names of this protein?
Coiled-coil domain-containing protein 187.
Protein: DJC10_RAT
Sequence: MGVWLNRDEFIRDVKRISLCLLVLYVVIVVGTDQNFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWSYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWREFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAAVKYNGDRSKESLVSFAMQHVRTTVTELSTGNFVNAIETAFAAGIGWLITFCFKGEDCLTPQTRLRLSGMLDGLVNVGWVDCDTQDSLCKSLDATASTTAYFPPGATLNNKEKSSVLFLNSLDAKEIYMEIIHNLPDFELLSANKLEDRLAHHRWLVFFHFGKNENANDPELKKLKTLLKNEHIQVGRFDCSSAPGICSDLYVFQSCLAVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPASDKEPWLVDFFAPWCPPCRALLPELRKASTLLYGQLKVGTLDCTIHEGLCNMYNIQAYPTTVVFNQSSVHEYEGHHSAEQILEFIEDLRNPSVVSLTPTTFNELVKQRKHDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSVDCQQYHSFCTQENVQRYPEIRFYPQKSSRAYQYHSYNGWNRDAYSLRSWGLGFLPQASIDLTPQTFNEKVLQGKTHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYPQTCQKAGIRAYPSVKLYLYERAKKSIWEEQINSRDAKTIAALIYGKLETFQSQVKRNKDEL
What is the function of this protein?
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.  Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR.  Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1.  Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate.  Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 10.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: HSCA_PSEFS
Sequence: MALLQIAEPGQSPQPHQRRLAVGIDLGTTNSLVAALRSGLSEPLPDADGQVILPSAVRYHADRTEVGESAKLAASADPLNTVLSVKRLMGRGLSDVKQLGDQLPYRFVGGESHMPFIDTVQGPKSPVEVSADILKVLRQRAETTLGGELVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAVAYGLDQHAEGLVAIYDLGGGTFDISILRLTGGVFEVLATGGDSALGGDDFDHTVAGWIISSAGLSADLDPGAQRNLLQTACAAKEALTDAATVEVSYGTWSAQLTREAFDALIEPMVARSLKACRRAVRDSGVELEDVGAVVMVGGSTRVPRVRDAVAEAFGRQPLTEIDPDQVVAIGAAIQADTLAGNKRDGGELLLLDVIPLSLGLETMGGLMEKVIPRNTTIPVARAQDFTTYKDGQTAMMIHVLQGERELISDCRSLARFELRGIPAMVAGAAKIRVTYQVDADGLLSVAARELASGVEASIQVKPSYGLTDGEIAKMLKDSFQYAGDDKVARVLREQQVDAQRLLEAVQGALDVDGERLLDAEERMVIDLQMQELAELIKGTDGYAIEQQTKRLSQVTDAFAARRMDQSVKAALAGRNLNELEE
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RBM48_PONAB
Sequence: MASSGGELGSLFDHHVQRAVCDTRAKYREGRRPRAVKVYTINLESQYLLIQGVPAVGVMKELVERFALYGTIEQYNALDEYPAEDFTEVYLIKFMNLQSARAAKRKMDEQSFFGGLLHVCYAPEFETVEETRKKLQVRKAYVVKTTENKDHYVTKKKLVTEHKDTEDFRQDFHSEMSGFCKAALNTSAGNSNPYLPYSCELPLCYFSSKCMCSSRGPVDRASDSSKDGRNHHKTMGHYNHNGSLQKTQINSFKNSVACPGAQKAVTSSEAVDRFMPRTTQLQERKRRREDDRKLGTFLQTNPSGNEVMIGPLLPDISKVDMHDDSLNTTANLIRHKLKEVISSVPKPPEDKPEDVNTSHPLKQRRRI
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
RNA-binding protein 48.
What is the protein family that this protein belongs to?
Belongs to the RBM48 family.
Protein: ABC3G_GORGO
Sequence: MTPQFRNTVERMYRDTFSYNFNNRPILSRRNTVWLCYEVKTKDPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRNVATFLAEDPKVTLTIFVARLYYFWDQDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYMLLHIMLGEILRHSMDPPTFTSNFNNEHWVRGRHETYLCYEVERLHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLHQDYRVTCFTSWSPCFSCAQEMAKFISNKKHVSLCIFAARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVYHQGCPFQPWDGLEEHSQALSGRLQAILQNQGN
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility.  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA (By similarity).
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3G, Deoxycytidine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Mainly cytoplasmic, small amount are found in the nucleus.
Protein: IF1_PHOPR
Sequence: MAKEDVIEMQGTVQDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_AFIC5
Sequence: MTTPFVLAVPSKGRLQENADAFFGRAGLTLAKPRGARDYRGTITGLDNVEIAYLSASEIAAQLARGQVHLGITGEDLVRETIADADKRVMLIEGLGFGYANVVVAVPQAWIDVRTMADLDDVATSFRVKHNRRMRVATKYINLTRHFFALHGIVDYRIVESAGATEGAPASGAAELIVDITTTGATLAANGLKMLDDGMMLRSQANLVASRAADWTPEARETARVILDHIASRARAAKYKEVRTCLPGCDAALLSEIEQHFGALAPFGTPPAGGILTLHCPPAQLYPLGTLLRARGAETVSIGSLDYVMARDNPLFSRLEAFLGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGA_CAEEL
Sequence: MLPRKLKIDSTELAEITNELVQFLNCLVLRSGGLKKEHIWVRNGRILDERTVFFEEKTMADVQIDCEGLILSPGFIDLQLNGGFGIDFSTYNSDDKEYQEGLALVAKQLLAHGVTSFSPTVITSSPETYHKILPLLKPSNASSEGAGNLGAHLEGPFISADKRGCHPEQLVITSLSPNPVEIIEHVYGSTENIAIVTMAPELEGAQEAIEYFVSTGTTVSVGHSSAKLGPGEMAVLSGAKMITHLFNAMQSYHHRDPGLIGLLTSSKLTPDHPLYYGIISDGIHTHDSALRIAYHTNSAGLVLVTDAIAALGMSDGVHKLGTQTIHVKGLEAKLDGTNTTAGSVASMPYCIRHLMKATGCPIEFALQSATHKPATLLGVSDEKGTLDVGRLADFVLIDKNVTVKATFCSGKRVFLAQD
What are the official names of this protein?
N-acetylglucosamine-6-phosphate deacetylase, GlcNAc 6-P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Protein: ERPA_PSEMY
Sequence: MSVETFTPAPLHFTQGAASKVKTLVDEEGNPRLKLRVFVTGGGCSGFQYGFTFDEDVAEDDTIVEREGVSLVVDAMSFQYLVGSEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NIGR2_PELNI
Sequence: GLLSKVLGVGKKVLCGVSGLC
What is the function of this protein?
Thanks to its single linear amphipathic alpha-helix, may integrate into membrane phospholipids, leading to lysis of the membrane.  Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans.  Has no hemolytic activity.
What are the official names of this protein?
Nigrocin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: DUT_LEPIN
Sequence: MKIFVQKLRPNAELPLLQTKQAAGYDIHACLDSKLVLEPGNVGLVPTGLSFAIPQEFHFEIRPRSGFSTKNRILIPNSPGTIDSDYRGELMIPLLNLGDSSFIIEHGMRIAQLLIRKTWYADWELVSEFADRTERGANGFGSTGH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RNY_GEOUR
Sequence: MKIDMMTMILAVIAAAIGFLIGNLLRKKSSDAIVASAEELAAKMVEESKRQAETITKEASLQAKDVVYQAKADFERETKDKRRDLQALEKRLQQKEENLDKKMNLFDQRDAEFLKREQGLAAKEQVLGQKDEKLNQLISEERTRLENISGMTAAEAKKILMETMENEAKLDAAKRIKAIEEEARETADKKSKEIMALAIQRYAGEYVAERTVSVVALPSDEMKGRIIGREGRNIRALEAATGIDLIIDDTPEAVILSGFNPVRREVAKLSLEKLIADGRIHPGRIEEVVAKAEEEVELAMKEAGEQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMAAELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELAKKYGESPKIVHAIMAHHEDEKPATVLAILVQAADALSGARPGARREMMETYVKRLDDLERIACSFSGVTNSFAIQAGREIRVMVSSEEISDERTLILAKDIAKKIETEMTYPGQIKINVIRETRATEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COAD_NEIM0
Sequence: MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYEKILAEHQHEN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_RHOP2
Sequence: MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPALPRTVVASEDAKFCSHSGIDWDSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVVRKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAEAGAAYAFGRSAAQLTPQEAALMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ASSY_CAMFF
Sequence: MQKKDVKKVVLAYSGGLDTSIILKWLQDEYKCEVVTFTADIGQGEEVEPARKKAISLGIKPENIFIEDLREEFVKDFVFPMFRANAIYEGEYLLGTSIARPLIAKRLVEIAAATKADCVSHGATGKGNDQVRFEIGAYALNPNIKVIAPWREWDLNSREKLLAYAEKNGIDISKKKGKSPYSMDANLLHISYEGLVLEDPNHAPEEDMWRWSVSPKNAPDESDIIEIEYKNGDPVAINAKSMKPHEILTELNRLGAKHGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITMDREAAHLKDELMPKYASLVYNGYWFSPERKMLQAAIDESQKNVNGTVRVELYKGNVMVIGRDSKTDNLFNEAYCTFEEDSVYDQKDANGFIKLNALRFIIAGKNGRKF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.