PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_PVMR
Sequence: MAVTYRTPMEDIVNCFEPATQAVIANSAATLYKNFEEQHCQYFNYYLSPLAKRKLSMAGIYLSPYSAVVHSHPVCKTLENYILYSVLPSYINSSFYFVGIKERKLQLLKSKCKNLDSVQVVNRYVTSADRMRYTNDFVPYGSYEHECLVHKGVGLDNEALRGLVGPLRRHKAKNLFFHDELHYWSSKVLIDFLDVMRPDKLLGTVVYPPELLFKPTRSLNEWCYTYDIVGDTLMFFPDGVQSEGYQQPLKGGYLLGARSLKLPDGTVYMVDVLCSKFPHHLISITKGEAAAPTHRAFGPFEAVASEALKATLSPDYPCAFPVSYEVVNKIYRYLRTLKKPDEQSAIAKLSQIIAEPSGREIDFVECFARLVIHNSSMCATIMPEQLKEFMGNWLGKMPSVLARRFSSVRAVCVNKFIRGLKPYSFTLRLNEITWWNIWENSYAWFFDTDAEVDVPEKLDSLFMGEGAGLVAHITSRPYVGTVPLADREWNALLCMDSQKLLHAMRRMFMRGAWGAHMCVISREFLLKYVEARLKSSCLIAKARRRGQHKEKLEAWEVLGLKSSDALFRAMTYLCNARLEPMFSESGLRFFLTRGRNNLYGLTNYTEGKRAVTGVQNLWSNVVHEVSTKRHKGMIRLEKARVTEQPRSEFASCVLEPEVWRDVEAALDIELGEVACACNARFVQGVVLSNQAGLNVREQVAGASVGLYTKDRSNLKWGNSELLSNGWGRSLSVWMEINSVSQKFDVAVRLSYSKETQMNVLLPSLDGIERGAGATVVNLRKCGAFIVRCARGWRLALAWMDHICLEVMANVAYGHECYMRSWGTMDVVVFLKRATVSEQVTFESAQEVGPIEGKSDSGAPGVGVNLDLGGVVGSEYPANGAERYKRVSGPGDGCCCWHSFAYLVGMHHMELKRLCTSHVFENAALNVELEQCKASGAFVTHAAILATALRLRAEIRVHNAGTGRVHRFAPKQKNMALDLWLESEHYEPQVLRNGCVIESVAQALGTRNADILAVVEERCCEEVVESVQAGLGLNLHHVEIVLQCFDIVGHCNLGDKEITLNAGGKMPFCFDISDEHMSFCGRRKDPICKLVSGALHGKMFAESALLDLENCGLKIDFEPNWNRAGMLADSMYQGATGVLGSALFNNKRNMREKFVRNVSLSLHAIVGTFGSGKSTLFKNLLKYGAGKSLDFVSPRRALAEDFKRTVGMNERGGRAKAGQENWRVTTLETFLARVEFLTEGQVVILDEMQLYPPGYFDLVVSMLKVDVRLFLVGDPAQSDYDSEKDRLVLGAMEENMSVVLGAREYNYKVRSHRFLNCNFIGRLPCEINKDDCTIDEPHIMRMHLENLLDVAEEYKSVVLVSSFDEKMVVCAHLPEAKVLTFGESTGLTFMHGTIYISAVSERTNERRWITALRRFRFNLCFVNCSGMDYQQLAGRYKGRVRSKFLCKTAIPDDLNSMLPGQALFKSEYPRLIGKDEGVREEKLAGDPWLKTMINLYQAPEVEIAEEPEVVMQEEWFRTHLPRDELESVRAQWVHKILAKEYREVRMGDMVSEQFTHDHTKQLGAKQLTNAAERFETIYPRHRASDTVTFLMAVKKRLSFSNPGKEKGNLFHAASYGKALLSEFLKRVPLKPNHNVRFMEEALWNFEEKKLSKSAATIENHSGRSCRDWPTDVAQIFSKSQLCTKFDNRFRVAKAAQSIVCFQHAVLCRFAPYMRYIEMKVHEVLPKNYYIHSGKGLEELDAWVKKGKFDRICTESDYEAFDASQDEFIMAFELELMKYLRLPSDLIEDYKFIKTSLGSKLGNFAIMRFSGEASTFLFNTLANMLFTFMRYNIRGDEFICFAGDDMCASRRLQPTKKFAHFLDKLKLKAKVQFVQFVNKPTFCGWHLCPDGIYKKPQLVLERMCIAKEMNNLSNCIDNYAIEVAYAYKLGEKAVNRMDEEEVAAFYNCVRIIVRNKHLIRSDVKQVFEVL
What is the function of this protein?
Protease: Thiol protease that cleaves the polyprotein.
What are the official names of this protein?
RNA replication polyprotein, ORF1 protein.
What is the protein family that this protein belongs to?
Belongs to the potexviruses/carlaviruses RNA replication protein family.
Protein: LEPA_METNO
Sequence: MTAKPIDTIRNFSIVAHIDHGKSTLADRLIQLTGALSAREMTEQVLDSMDIERERGITIKAQTVRLDYTAQDGRTYILNLMDTPGHVDFTYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQAIDANHEIVPVLNKIDLPAAEPDRVKQQIEEVIGIDASEAVPISAKTGLNIEAVLEAIVAKLPPPKGDRAAPLKALLVDSWYDVYLGVVVLVRIVDGVLKKGMTIRMMGADAVYGVDRIGVFRPKMQDVAELGPGEVGFLTASIKEVADTRVGDTITEDRRPTDSPLPGFKPVQPVVFCGLFPVDAAEFENLRAAMGKLRLNDASFSYEMETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLISTAPSVVYRLNMSDGTMRELHNPADMPDVMKIDTIEEPWIRATILTPDDYLGSVLKLCQDRRGTQIDLNYVGKRAMVVYDLPLNEVVFDFYDRLKSISKGYASFDYHISDYREGDLVKMSILVNSEPVDALSMLVHRTRAESRGRAMCEKLKDLIPRHLFQIPVQAAIGGKIIARETIRALSKDVTAKCYGGDISRKRKLLDKQKEGKKRMRQFGKVEIPQEAFIAALKMDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GMPP_MYCTU
Sequence: MATHQVDAVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEHVILGTSYKPAVFEAEFGDGSALGLQIEYVTEEHPLGTGGGIANVAGKLRNDTAMVFNGDVLSGADLAQLLDFHRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINAGCYVFERNVIDRIPQGREVSVEREVFPALLADGDCKIYGYVDASYWRDMGTPEDFVRGSADLVRGIAPSPALRGHRGEQLVHDGAAVSPGALLIGGTVVGRGAEIGPGTRLDGAVIFDGVRVEAGCVIERSIIGFGARIGPRALIRDGVIGDGADIGARCELLSGARVWPGVFLPDGGIRYSSDV
What is the function of this protein?
Catalyzes the formation of GDP-mannose from D-mannose-1-phosphate and GTP (PubMed:11302803, PubMed:34644596).  Plays an important role in the synthesis of different glycoconjugates which are responsible for cell wall structure, virulence and immunomodulatory activity of M. tuberculosis (PubMed:34644596).
What are the official names of this protein?
Mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, GMP, GMPP.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: PCNA_METS3
Sequence: MFKAELSDSSILKTSFDAISSIVDEVQIQTDSEGMRLDALDRSHITFVHLELKASLFDEYVCDVPEKINIDTGEFMSVLKRAKSQDRVIMSLDEGNFIITFEGDATRTFKIRLIDIEYDNPTPPELEHPASFKVHFGILKDAINDIDIFSDKIALQVDEDYFRASADGEFGDASVKYLHGENINTQEKSLFSLDKIREMLKADKFSEEAEIGLGTDMPLKLTLNMVTGDGKLSFLLAPRLESDE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: VM2MB_GLOBR
Sequence: MIQVLLVIICLAAFPYQGTSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLPKNKALPSKDYIETHYSPDGRKITTNPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGETYLIEPLKLSNSEAHAVYKYEDVEKEDEAPKMCGVTQNWESYEPIKYEDVEKEDEAPKMCGVTQNWESYEPIKKASQSNLTPAHQRYIELVIVADHGMFTKYNGDSDKIREWVRQMVNTVDEIYSYMYIDVALAGLQIWSNEDLINVQPAAPHTLDSFGKWRERDLLHRIHHDNAMLLTAIDFDGPTIGLAYVGTMSNPKGSTGVVQDHSTINFRVAVTMAHEIGHNLGIHHDTGSCSCGGYSCIMSPVISHEPSKYFSDCSYTQCWDFIMNQKPQCILNKPLRTDTVSTPVSGNELLEAGEECDCGSPGNPCCDAATCKLRQGAQCAEGLCCDQCRFMKEGTICRRGRGDDLDDYCNGISAGCPRNPFHA
What is the function of this protein?
Inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_SHEAM
Sequence: MATVNQLVRKPRAPKVDKTNVPALEACPQKRGVCTRVYTTAPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTIRGALDCAGVNARRQARSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: YIV5_YEAST
Sequence: MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANEERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKLALHGIPDGVNGQYLSYNDPALADFMP
What are the official names of this protein?
Uncharacterized oxidoreductase YIR035C.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RUVC_XANAC
Sequence: MTRILGIDPGSQRTGIGIIDIDEGGRSRHVHHAPLMLLGEGDFSQRLKRLLQGLGELIEIYRPDEVAIEKVFMGKSAASALKLGHARGAAICAVVMRDLPVHEYAAKEIKLALVGKGGADKVQVQHMVGIMLNLNGKLQPDAADALAVAITHAHVRATAQRLGVNTQQAWSRKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PSD_STRAW
Sequence: MPHSQTSAPRGRVRLARGASPWLLPTVATAALSLVRARRSGAAKAVAVPATALAAGMLWFFRDPEREITQGRVISPADGVVQSIMPWKDGRTRVAIFMSPLNVHVNRAPLSGTVTSVEHIPGGFVPAFNKESENNERVVWHFDTELGDIEMIQIAGAVARRIVPYVPQGTKVEQGDRIGLIRFGSRVDIYLPEGVDVDVEVGQKTVAGVTRIDRD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SECB_PSESM
Sequence: MTDQPNNGAVANEENGPQFSLQRIYVRDLSFEAPKSPAIFRQEWTPTVSLDLNTRQKPLEGDFYEVVLTLSVTVNNGEEVAFIVEVQQAGIFLIKGLDDAAMSHTLGAFCPNILFPYAREAIDNLVVRGSFPALMLAPVNFDALYAQELQRMQEAGETPMPTVQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEP8B_XENLA
Sequence: MAATDVERASNEEKRSLALSGHVGFDSLPDQLVGKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFETEEASHYENGVRLRPRTYELQESNVHLKLTIVDTVGFGDQINKDDSYRSVVDYIDTQFETYLQEELKIRRSLFNYHDSRIHVCLYFITPTGHSLKSLDLVAMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDDAVAEINSVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDNDPDTQPFSLQETYEAKRKEFLSELQKKEEEMRQMFVNKVKETESELKERERELQEKFMQLKRIHQEESKKVEDKRRDLEEEMNAFNRRKVAMETLQSQSFQATSQQPLKKDKDRKN
What are the official names of this protein?
Septin-8-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Protein: DNAA_BRADU
Sequence: MNTSEQDRWSRVKGRLRSSVGEDIYTSWFARMDLEDVQDESVRLSVPTRFLKSWIQAHYAERVLSCWQAEMPEVHRIDLTVRSAVRPVAPPKEAPAPVETRRAPAPELRSTATAPVSANHDALGGSPLDPRLTFASFVIGRSNTLAHAAARQVAEGRRGDPVMFNPLYIHAGVGLGKTHLLQAVTWAGNSGNERKVLYLTAEKFMYGFVAALKTQTALAFKEALRGIDVLVIDDLQFLQGKSTQAEFCHTLNALIDAGRQVVIAADRPPSDLESLDDRVRSRLAGGLVVEMGSLGEELRHGILKSRVAAARAHHATFDVPEEVLHYLARTITHNGRDLEGAINRLLAHSKLNNQPVTLEMAEREVRDLVRPQEPKRIKIEDIQRVVARQYNVSRSDLLSSRRTANVVRPRQVAMYLAKTLTLRSLPEIGRRFGGRDHTTVLHAVRKIEALVSKDTALSEEVESLKRQLQE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_HISS2
Sequence: MITIKKGLDLPIAGKPEQVIHNGNAVKEVALLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGIVFTAPASGTVTAINRGAKRVLQSVVIKVEGNEQITFTQYNEDELKKLTSEQVRQNLQSSGLWTALRTRPFSKVPASDAVPSSIFVNAMDTNPLSANPEIVLKEHWQDFTDGLTVLSRLHEGKLHLCKAGDSNIPTIDLPNLAVHDFSGPHPAGLSGTHIHFIDPVSATKSVWYLNYQDVIAIGKLFTTGEIYTDRVVSLAGPQVKNPRLIRTQLGANLSHLTENELSAGENRVISGSVLSGNTAIGPYNYLGRYALQVSVIAEGREKEFLGWIMPGKNKFSITRTVLGHFSSKLFNFTSAVNGGHRAMVPIGAYERVVPLDIIPTLLLRDLASGDTDSAQALGCLELDEEDLALCTFVCPGKNEYGPMLRAALDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: DCTA_ECO24
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCRB1_CRIGR
Sequence: MGGSARARWVAVGLGVVGLLCAVLGVVMILVMPSLIKQQVLKNVRIDPSSLSFAMWKEIPVPFYLSVYFFEVVNPSEILKGEKPVVRERGPYVYREFRHKANITFNDNDTVSFVEHRSLHFQPDRSHGSESDYIILPNILVLGGAVMMESKSAGLKLMMTLGLATLGQRAFMNRTVGEILWGYEDPFVNFINKYLPDMFPIKGKFGLFVEMNNSDSGLFTVFTGVQNFSKIHLVDRWNGLSKVNYWHSEQCNMINGTSGQMWAPFMTPQSSLEFFSPEACRSMKLTYHDSGVFEGIPTYRFTAPKTLFANGSVYPPNEGFCPCLESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPDPREHSLFLDIHPVTGIPMNCSVKLQISLYIKAVKGIGQTGKIEPVVLPLLWFEQSGAMGGEPLNTFYTQLVLMPQVLQYVQYVLLGLGGLLLLVPVIYQLRSQEKCFLFWSGSKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL
What is the function of this protein?
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells.  Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux.  Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL.  May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.
What are the official names of this protein?
Scavenger receptor class B member 1, SRB1, HaSR-BI, SR-BI.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
Protein: MIAA_RHOPS
Sequence: MFGLQMSVATSDMNGSDPGQPGQRPAAVLIAGPTASGKSALALRLAQARDGVVINTDSMQMYRDLRIITARPTAEEEALAAHRLYGSVDAAVNFSAGAYVEAAAGALAEARAAGRLPIFVGGTGLYFKALTRGLSAVPPVAAEVRDAVRLRLDRDGVLALHAELARHDPAGAARLAPADRSRIARALEVVLATGRPLADWHNQASPPLLPPEGFVAMFLAPEREALYGRIDARFAAMLQAGALEEVAALAARNLDPLLPAMKAHGVPALIRHFRGELSLEEAAAIGAADTRHYAKRQFTWFRHQLPEFRWVTPEQAESGLLGT
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYI_HAEI8
Sequence: MTVDYKNTLNLPETSFPMRGDLAKREPDMLKNWYEKNLYQKIRKASKGKKSFILHDGPPYANGNIHIGHAVNKILKDIIIKSKTALGFDSPYIPGWDCHGLPIELKVEGLVGKPNEKISAAEFRQKCREYASEQVEGQKKDFIRLGVLGDWDNPYLTMNFDTEANIIRTLGKVIENGHLYKGSKPVHWCLDCGSSLAEAEVEYEDKVSPSIYVRFPAESAVEIEAKFSAQGRGQGKLSAIIWTTTPWTMPSNRAIAVNADLEYNLVQLGDERVILAAELVESVAKAVGVEQVEILGSVKGADLELSRFHHPFYDFTVPVILGDHVTTDGGTGLVHTAPDHGLDDFIVGKQYDLPMAGLVSNDGKFISTTEFFAGKGVFEANPLVIEKLQEVGNLLKVEKIKHSYPHCWRHKTPIIFRATPQWFIGMETQGLRQQALGEIKQVRWIPDWGQARIEKMVENRPDWCISRQRTWGVPMTLFVHKETEELHPRTLELLEEVAKRVERAGIQAWWDLDEKELLGADAETYRKVPDTLDVWFDSGSTYSSVVANRLEFNGQDIDMYLEGSDQHRGWFMSSLMLSTATNSKAPYKQVLTHGFTVDGQGRKMSKSIGNIVTPQEVMDKFGGDILRLWVASTDYTGEMTVSDEILKRAADSYRRIRNTARFLLANLNGFDPKRDLVKPEEMISLDRWAVACALDAQNEIKDAYDNYQFHTVVQRLMRFCSVEMGSFYLDIIKDRQYTTKADSLARRSCQTALWHIAEALVRWMAPILSFTADEIWQHLPQTESARAEFVFTEEFYQGLFGLGEDEKLDDAYWQQLIKVRSEVNRVLEISRNNKEIGGGLEAEVTVYANDEYRALLAQLGNELRFVLITSKVDVKSLSEKPADLADSELEGIAVSVTRSNAEKCPRCWHYSDEIGVSPGHPTLCARCVENVVGNGEVRYFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCH34_STACH
Sequence: AGPIASRQIVPNYPASSTSKGFHLVVNVTDPSADFTPSINNFYVNSIHVGAALNYVGVTAVPGRIFYQNGTAEEIRYAQSTVISDGATPPVPFGLSLRPDEGSDVVSTARLDAGPGTTGVRVSRFPEPYRFLQPETFLACNESLAYYQGDYFTVIKQADVTVGDDGSIDYNVPDNCISVRLIPECTELNELPEDAYASHEFAADTQCYDDVSALNWSEYGP
What are the official names of this protein?
Antigenic protein SchS34, 34 kDa secretory protein, SchS34.
What are the subcellular locations of this protein?
Secreted. Spore. Spore wall. Cytoplasm. Note=Localizes primarily in the outer and inner layers of the spore wall and on the external wall surfaces. In the mouse lung spreaded with spores, located in spore walls along the outside surface of the outer wall and in the intercellular space surrounding spores, slowly diffusing to the surrounding tissues of mouse granuloma.
Protein: HIS9_HALH5
Sequence: MGKHDGHVHTPFCPHGTKDSFDAYCERAISLGFTSLSFTEHAPLPKGFTDPTPAQDSSIGWNELDDYIHTLSSIKKAYRDQLTIYIGLEVDFIEGFEEEICTFLNEYGPLLDDSLLSVHFLKHSDRYFCIDYSPDVFAVAIRTFGSIQAVYDTYYRTLERSITSELGPYKPKRIGHMTLVNKFQKKFPAPSTEHQKKSQLEILQLVKKHGYSLDYNGAGFIKPLCGESYPPESIAKEAVALGIPLIYGSDAHQAKALATGWEQMTPTLKNQDE
What are the official names of this protein?
Histidinol-phosphatase, HolPase.
What is the protein family that this protein belongs to?
Belongs to the PHP hydrolase family. HisK subfamily.
Protein: TOM40_BOVIN
Sequence: MGNVLAASSPPAGPPPPPAPPLVGLPPPPPSPPGFTLPPLGGGLGAGAGTGRGSERTPGTAAASAGGTADDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGAVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG
What is the function of this protein?
Channel-forming protein essential for import of protein precursors into mitochondria.  Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM40 homolog, Translocase of outer membrane 40 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom40 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=Associates with the mitochondria-associated ER membrane via interaction with BCAP31.
Protein: TSAD_STRSY
Sequence: MMKDRLILAIETSCDETSVAVLRNDAELLSNVIASQIASHQRFGGVVPEVASRHHVEVITACIEEALLEAEVTAEDLTAVAVTYGPGLVGALLVGISAAKAFAWANGLPLIPVNHMAGHLMAARAVKELEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLPYPAGRVIDELAHEGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLYHNAQQKGETLSNADLSASFQACVMDILMAKTKKALEQYPVKTLVVAGGVAANQGLRERLAAEITDVEVIIPPLRLCGDNAGMIALAAVSEYNKENLAGWDLNAKPSLAFENL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SYNS9
Sequence: MNPSRCRILAVGKVRRDWIQKGIELYLKRLPGLTVTELRDSSPEKEADSIRAALRPDETLIALMEQGECLGSIPFARRLKQFENERLVFVIGGADGLTAELKLQAQWQLSLSPLTFPHELARLMLVEQLFRAQSIVQGRPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.