PharMolix/UniProtQA huggingface dataset:
Protein: KDGD2_STRCO
Sequence: MTSAGPGSDPGTGRAAVVRRLREGMAASVLSFPLTSFHEDGSFDADGYRAYVAERLAAGPGALFPACGTGEFFSLDEDEYRQAVAIAVEETAGSVPVVAGTGYGWAQALRFARIAEDAGADALLVMPHYLTAAPQDGLVAQMERIAAGTRLPLIAYQRGQVAYTAESVRRLTRVPGVIGLKDGHSDLDRLQRAVLAAPDDFLFFNGAATAEVQARAYAAVGVPAYSSAVHAFAPEIANAFLAALRGGDTGTVDKLLRDFYVPLVELRDRVPGYAVSLVKAAARLRGCPVGPVRAPLTDPSPADLAALTTLLTTGLDLVGAAL
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase 2, 5-keto-4-deoxy-glucarate dehydratase 2, KDGDH 2.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: DRL25_ARATH
Sequence: MEKQDQTSREEILKKIMDSLGQDGVPSKTVLVGEAGIGKTWLAKEVSQRVTQEKYNVLWLHLNKKIEDEKSLYEILAAQLSIIYEFEEGEEPDELDYPLESLKEKIKEEMIKHKKDNLLLILDDEGSMTTEEDVMQELNLQDFLKEYSAVKILVTRRDEREEKESTTIKVGPLTEKESLDLLHDAEDLLTSFTSEDWPVLLKRLCDNKEIKEPTLMSCILSKSKGLPAAIVVLIKSLNSIKSMSAKQRKIFKELILSSKSLDEAAASKNAIDRSRYNPVLQLSYELLKPDETVKRPVIACFWHILDFYKYSGCAYYRDLIVHWMLEGYFDPVKSVDKAYQEGHSILMDFMNRGILKIQEDNMVVPEFSMSNLLDLQDCGFFGRSSLGFDRVYGGDKRKGLGKIILIDDMIQTIQSKKKNITTIIASGNRLRREVHGKFFEKPEMQDLEVVVLFEPTFHELVLSLSKLKKLRVLVIRDCDLIDNIDKLSGLQGLHVLEVSGASSLVNIPDDFFKNMTQLQSLNLSGLAIKSSPSTIEKLSMLRCFILRHCSELQDLPNFIVETRKLEVIDIHGARKLESYFDRVKDWKDYKGKNKNFAQLQLLEHLDFSETKIIRLPIFHLKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMLEVCLEEKKELRILDMSKTSLPELADTIADVVNLNKLLLRNCSLIEELPSIEKLTHLEVFDVSGCIKLKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKELIIRKCSKLKTLPNLEKLTNLEIFDVSGCTELETIEGSFENLSCLHKVNLSETNLGELPNKISELSNLKELILRNCSKLKALPNLEKLTHLVIFDVSGCTNLDKIEESFESMSYLCEVNLSGTNLKTFPELPKQSILCSSKRIVLADSSCIERDQWSQIKECLTSKSEGSSFSNVGEKTREKLLYHGNRYRVIDPEVPLNIDIVDIKRSTDLKTEYIAKAEYVSIAENGSKSVSSLFDELQMASVKGCWVERCKNMDVLFESDEQLEKEKSSSPSLQTLWISNLPLLTSLYSSKGGFIFKNLKKLSVDCCPSIKWLFPEIPDNLEILRVKFCDKLERLFEVKAGELSKLRKLHLLDLPVLSVLGANFPNLEKCTIEKCPKLKAREDEPRIGARITDEISEDQPHKNTIGPETQTPTQPTKATDTV
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Putative disease resistance protein At4g19050.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: RR7_ORYSI
Sequence: MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGGGGAIRKKEATHRMAEANRALAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DPO3X_BACSU
Sequence: MSYQALYRVFRPQRFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKIFAKAVNCEHAPVDEPCNECAACKGITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTYKVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPHKIPLTIISRCQRFDFKRITSQAIVGRMNKIVDAEQLQVEEGSLEIIASAADGGMRDALSLLDQAISFSGDILKVEDALLITGAVSQLYIGKLAKSLHDKNVSDALETLNELLQQGKDPAKLIEDMIFYFRDMLLYKTAPGLEGVLEKVKVDETFRELSEQIPAQALYEMIDILNKSHQEMKWTNHPRIFFEVAVVKICQTSHQSAADLPEVDMLMKKIQQLEQEVERLKTTGIKAAAESPKKEAPRVPKGGKSNYKAPVGRIHEILKEATRPDLDLLRNSWGKLLAHLKQQNKVSHAALLNDSEPVAAGSAAFVLKFKYEIHCKMVAEDNNGVRTNLEQILESMLGKRMDLIGVPEAQWGKIREEFLEDHQQENEGSNEPAEEDPLIAEAKKLVGADLIEIKD
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
What are the official names of this protein?
DNA polymerase III subunit gamma/tau.
What is the protein family that this protein belongs to?
Belongs to the DnaX/STICHEL family.
Protein: DUT_ZYMMO
Sequence: MKIKLEIKRLPHGANLPFPSYASEGAAGMDVVSAEDVILQPMQRYPVKTGFAVAIPNGYEIQVRARSGLALKHGIACPNAPGTIDSDYRGEVKILLINLGSEAFEIKRGDRIAQLILASVTQAVFCEVTDLDDTQRGHNGFGSTGI
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL7_ACIC5
Sequence: MADLQQLEDQIVSLSLLDAAALVKKLEERLGVSAAAAAPVVVAGGAAGAGAAEAAAEQTEFTVILKDAGANKINTIKAVREVTALGLKEAKDLVDGAPKPLKENISKEDAEAIKKKFDGVATIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GLGX_YERE8
Sequence: MTTLTSGSPTPMGAHFDGVGINFTLFSAHAEQVELCLFDDNNQELRIPLPARSGDIWHGYLPGGKPGQRYGYRVSGPFNPQQGHRFNPHKLLIDPYARALDRKVGDDPSLQGGVSQPDYRDSAAVAPKCIVVHEEYDWQGDRRPTIPWGNTVIYEAHVRGLTQLHPDIPADLRGTYAGLAHPAMIQYLQKLGITTLELLPVQFHIDEPRLQKMGLSNYWGYNVLAPYAVDPDYASGREGISPLRELRDAVKALHQAGIEVILDVVFNHSAELDVFGPTLCQRGIDNASYYWLTSEGEYDNMTGCGNTLRLSQPYVMQWVLDCLRYWVDSCHIDGFRFDLGTVLGRSPAFDQHAPLFAALAADKQLCNCKMIAEPWDIGLGGYQLGNFPTGFSEWNDQYRDAMRRFWLRGDLPLGQFAQHFAASSNLFKHRERLPSASINQITAHDGFTLQDLLCFNQKHNQINGEENRDGSDNNLSNNFGSEGLVADDAIWQRRKACQRALLTTLLLSQGTPMLLAGDEHGHSQQGNNNAYCQNNILTWLDWGSADRELTAFTAELIRLRQQIPALIQDSWWEDGDGNVQWLDSQGEALSDGAWEQGCQKQLQIRLSQRWLVVINATDQACEMHLPVGEWVVIPPFEPSEHTEPLTVWNGSAHTVCVLTQKF
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: NMD5_YEAST
Sequence: MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAGARQGSNELLDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIRVLKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFQDGKYMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQEVLAISDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEEFLTQFLQVVFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDFWDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTLQSAVGDYNNIMLDNALQIESCLRIFSSIIDRLITKDSPFASEMEKFILTYVLPFFKSQYGFLQSRVCDICSKLGSMDFKDPVITSTIYEGVMNCLNNSSNSLPVELTAALALQTFISDDQFNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSNLDPDSFTNVDSIPDESDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIEDFYRECCEFVENSTFLLRDITPISWKILELIGECNRKPDSMVSYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQYRERLLADVVGSILTQKNELKTNVVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDYIPNYKRCYDIKLSVLALLKIILKLESNDYSVLNLENLVPQLGSIVTQLASRLPTALRQLANQRKEFSSSGFEEDTKWDENFLDVGDDDENDDEGDLTEKYLELIKNRADSLDFVDGYDAKETFDDLEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRYQGILRHLTPADQELFMGIMNA
What is the function of this protein?
Active in protein import into the nucleus.  Its major import substrate is transcription elongation factor TFIIS.
What are the official names of this protein?
Nonsense-mediated mRNA decay protein 5, Karyopherin-119.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS2_DEIRA
Sequence: MSYISMKQLLEAGVHFGHETKRWNPKFKKFIFAERNGIFIIDLQKTLKQVDRSFDYIKDLAERGGVILFVGTKKQAQEIVELEARRTGMPYVTSRWLGGMLTNFKTMRTRIDRLNELDDLFESERINDRPKAERIQLASERERLLRFVGGIRKMNRLPDAIFVVDPTKEVIAVQEANKLGIPVIALADTDSDPDVIDYIVPGNDDAIRSIQLITHRVGDLLVEARGGHEDVSAGPVEEQSDEAQAAEQGTEGDTAQLTSSQGRS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NAGB_CORGB
Sequence: MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCKAFLLDEYVGLTRDDENSYFKTIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAAESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVEDNARFFNTIEEVPTHALTQGLGTLSRAQNIVLVATGEGKADAIRGTVEGPVTASCPGSILQMHNNATIIVDEAAASKLENADHYRLMEQLKLR
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RNZ_SULIM
Sequence: MIQIFFLGTGAGSPSKKRKLPAFLVRREGLNILLDCGEGTQYTLMNNKLGINSIKIIGITHMHGDHVFGLLGVIASMGLLDRKETLYILGPRDLKDFLYTSFEYSKFNPSFKIEFIDNYNDQNITIATFKTCHTVESQGYLISERDRVKIDEEKLEKEKIKDWRVMRKLKEGKTVEYNGKFLKPEDYLVIKRGLKVAYTGDTIPCQSVIESVKGVDLLIHDSTFLNEPSACTYGHSNVADAAKVALEASVKLLALTHISPRYEDVTEHLKVARRIFPKSILPDDLSYITLK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: KAXU0_TITST
Sequence: KRKCGLCKYRCCSGG
What is the function of this protein?
May block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Peptide 2900, Potassium channel toxin alpha-KTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family.
Protein: RSGA_PHYAS
Sequence: MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVLYGMCYDKYLIYAILPRKNELKRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLDVILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQIGIGVLKNIFEQKITVLAGQTGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGGFSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEIKKEKKIYVKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECCB2_MYCTO
Sequence: MPLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDSAIIGDRDSGALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADKPVVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEPLRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVTSTSGVITAESRESLFWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPTLGQVAIVTTTAKAGA
What is the function of this protein?
An ATPase (By similarity).
What are the official names of this protein?
ESX-2 secretion system ATPase EccB2, ESX conserved component B2, Type VII secretion system protein EccB2, T7SS protein EccB2.
What is the protein family that this protein belongs to?
Belongs to the EccB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ERA_HALOH
Sequence: MSYKSGFVSVIGRPNVGKSTLINNLIGQKVVITSPRPQTTRNSVRGIYTRPEGQIVFVDTPGIHKARNKLDNYMLEKAYESLEDIDVIIFMVDGNYSFGKGDEFIYNQIKGVRVPVIVAMNKIDRINKEIVMERQKNYEERTGFPVIPISASRGTNLDTLVEEIFTFLPEGPQYYPEDMVTDQIEQFVVAELIREKVFILTREEVPYGVAVKIEEMKERDNSTMYIRANIYAEKKSHKKIIIGHKGKMIKKIGRLAREEIEKLLQTKVYLDLWVKIEKDWREKEGLVKRMGYKG
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: P2RY6_MOUSE
Sequence: MEQDNGTIQAPGLPPTTCVYREDFKRLLLTPVYSVVLVVGLPLNICVIAQICASRRTLTRSAVYTLNLALADLMYACSLPLLIYNYARGDHWPFGDLACRFVRFLFYANLHGSILFLTCISFQRYLGICHPLASWHKRGGRRAAWVVCGVVWLAVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFIALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFAISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASVNSVLDPILFYFTQQKFRRQPHDLLQRLTAKWQRQRV
What is the function of this protein?
Receptor for extracellular UTP > ADP = 2-methylthio-ATP > ADP-beta-S > ATP = ATP-gamma-S.  The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.  Functionally coupled to phospholipase C (By similarity).
What are the official names of this protein?
P2Y purinoceptor 6, P2Y6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EDF1_RAT
Sequence: MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK
What is the function of this protein?
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities.  Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1.  Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm.  Might function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism (By similarity).
What are the official names of this protein?
Endothelial differentiation-related factor 1, EDF-1, Calmodulin-associated peptide 19, CAP-19, Multiprotein-bridging factor 1, MBF1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin (By similarity). Localized mainly in soma and dendritic processes of neurons.
Protein: CYB_CEREN
Sequence: MINTRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGILLLVLFLMLLVLFAPDLLGDPDNYTPGNPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALISSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFFIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRD_HELPJ
Sequence: MLYSLVKKYLFSLDAEIAHEKVCQILRTLSSSPFLCRLIHSQWGYKNPKLENEILGLNFPNPLGLAAGFDKNASMLRALIAFGFGYLEAGTLTNIAQSGNEKPRLFRHIEEESLQNAMGFNNYGAILGVRAFNRFAPYKTPIGINLGKNKHIEQAHALEDYQAVLNQCLNIGDYYTFNLSSPNTPNLRDLQNKVFVNELFCMAKEMTHKPLFLKIAPDLEIDSMLEVVNSAIEAGANGIIATNTTIDKSLVFAPKEMGGLSGKCLTKKSREIFKELAKAFFNKSVLVSVGGISDAKEAYERIKMGASLLQIYSAFIYKGPNLCQNILKDLVKLLQKDGFLSVKEAIGADLR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: POXB_STRPN
Sequence: MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKDIRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAILGSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVVEIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGVKAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLFLGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPVESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTTQTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPDVITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFTVDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKEKYEAEELVPFRLFLEEEGLQSRAIK
What is the function of this protein?
Important for the aerobic growth.  Decarboxylates pyruvate in four steps.  The energy released is partially stored in acetyl phosphate (By similarity).
What are the official names of this protein?
Pyruvate oxidase, Pyruvic oxidase, POX.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: PYRB_ANAPZ
Sequence: MKKLNKLLRIQSLSDVDIENIVALAHRYLQDSSANNVLQGRVIANLFFENSTRTLLAFEIAEKSLGAVSVTLNVETSSMKKGESVSDTLSTLSAMGVDLVVVRSGFSGFIDEVVERVGDCCVINAGDGNHEHPTQALTDYATIRYLKGKYIEGLNVTICGDIFHSRVARSNMRLLSRYGANINVVTPPCWSASVPSSNVTKITHSLEEGIKDADVIMLLRIQKERMSGASFISANEYSRHYMLDNAKLSIAKDDVIIMHPGPMNRGIEISDEVADASSSILLQVKMGVAVRKAILHYMLG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SH3R2_HUMAN
Sequence: MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRVFKAHKELRCPECRTPVFSNIEALPANLLLVRLLDGVRSGQSSGRGGSFRRPGTMTLQDGRKSRTNPRRLQASPFRLVPNVRIHMDGVPRAKALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLPQPPPLCRALYNFDLRGKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDKVGIFPILFVEPNLTARHLLEKNKGRQSSRTKNLSLVSSSSRGNTSTLRRGPGSRRKVPGQFSITTALNTLNRMVHSPSGRHMVEISTPVLISSSNPSVITQPMEKADVPSSCVGQVSTYHPAPVSPGHSTAVVSLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWLRGVSLVTGRVGIFPNNYVIPIFRKTSSFPDSRSPGLYTTWTLSTSSVSSQGSISEGDPRQSRPFKSVFVPTAIVNPVRSTAGPGTLGQGSLRKGRSSMRKNGSLQRPLQSGIPTLVVGSLRRSPTMVLRPQQFQFYQPQGIPSSPSAVVVEMGSKPALTGEPALTCISRGSEAWIHSAASSLIMEDKEIPIKSEPLPKPPASAPPSILVKPENSRNGIEKQVKTVRFQNYSPPPTKHYTSHPTSGKPEQPATLKASQPEAASLGPEMTVLFAHRSGCHSGQQTDLRRKSALGKATTLVSTASGTQTVFPSK
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity (PubMed:24130170).  Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169).  Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170).  Inhibits PPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623).
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF2, Heart protein phosphatase 1-binding protein, HEPP1, POSH-eliminating RING protein, Protein phosphatase 1 regulatory subunit 39, RING finger protein 158, RING-type E3 ubiquitin transferase SH3RF2, SH3 domain-containing RING finger protein 2.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_RHIL3
Sequence: MADDTTDTKSSNQMWGGRFASGPDAIMEEINASIGFDKKLFAQDIRGSIAHATMLAHQEIISAEDKDKIVHGLNTILSEIESGNFEFSRQLEDIHMNVEARLATLIGPAAGRLHTARSRNDQVALDFRLWVKEELQKTEQMLTGLIAAFLDRAEEHAESVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDRSRVRHAIEHLDESPIGAAALAGTGYPIDRHMTAKALGFREPTRNSIDTVSDRDFAIEFLSIAAIAGMHLSRLAEEIVIWSTPQFGFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAESLELAIAAMTGMVRDMTVNTARMKAAAGSGYSTATDLADWLVREAGLPFRDAHHVTGRAVALAESKGCDLAELPLSDLQAIHADITDKVYDVLTVEASVASRKSFGGTAPSEVRRQIAFWRARN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSMT1_PETHY
Sequence: MEVVEVLHMNGGNGDSSYANNSLVQQKVILMTKPITEQAMIDLYSSLFPETLCIADLGCSLGANTFLVVSQLVKIVEKERKKHGFKSPEFYFHFNDLPGNDFNTLFQSLGAFQEDLRKHIGESFGPCFFSGVPGSFYTRLFPSKSLHFVYSSYSLMWLSQVPNGIENNKGNIYMARTSPLSVIKAYYKQYEIDFSNFLKYRSEELMKGGKMVLTLLGRESEDPTSKECCYIWELLAMALNKLVEEGLIKEEKVDAFNIPQYTPSPAEVKYIVEKEGSFTINRLETSRVHWNASNNEKNGGYNVSRCMRAVAEPLLVSHFDKELMDLVFHKYEEIVSDCMSKENTEFINVIISLTKIN
What is the function of this protein?
Converts benzoic acid into the volatile ester methyl benzoates (PubMed:14630969).  This scent, mostly produced in a rhythmical, diurnal manner, attracts the pollinators (PubMed:14630969).
What are the official names of this protein?
S-adenosyl-L-methionine:benzoic acid/salicylic acid carboxyl methyltransferase 1, PhBSMT1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: CALC_HORSE
Sequence: MGFWKFSPFLPLSILVLYQVGIIQAAPFRSALESLPDPAVLPEEESRLLLAALVKDYVQMKVRALEQEQETGGASLDSPRAKRCSNLSTCVLGTYTQDLNKFHTFPQTAIGVGAPGKKRVMARGLERDHGPHIGTSQDAY
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUBP2_TRIAD
Sequence: MAEEGAQKATGKIKSVVLILSGKGGVGKSTVASQIALELANGGNKVGILDVDLCGPSIPRVLGLEDKDVHQCADGWIPVYADKNEKLAVMSIGFLLRNSKDAVVWRGPKKNAMIKQFLSDVVWGDLDYLIIDTPPGTSDEHITVAENVRGLNLTGAVMVTTPQAVALGDVRREITFCKKVGIPIVGIVENMSGYTCPNCSECTNIFSKGGGEALAQLTQVPFLGCLPLDPKLTMSIEDGKSFTELYSESPTALAIREIIRPLITS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_VIBPA
Sequence: MINEIKKDAQERMDKSVEALKNNLSKVRTGRAHPSLLSGISVEYYGAATPLNQVANVVAEDARTLAITVFDKELTQKVEKAIMMSDLGLNPMSAGTIIRVPLPPLTEERRKDLVKIVRGEAEGGRVAVRNIRRDANNDLKALLKDKEISEDEDRKAQEEIQKLTDVAVKKIDEVLAAKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.