PharMolix/UniProtQA huggingface dataset:
Protein: FUT10_XENTR
Sequence: MNRMWEKKFWISCFFIILFFILVTLQVMVELGRFEKRETKSFTVIDIKEQKKPLLKHIKEKSNSRLRHLKDNYPIMLWWSPLTGENGRLGQCGTDTCFFTINRTYLQDPMTKAILFYGTDFNMTSLPLPREISHEWALFHEESPKNNYKLFHEPAITLFNHTATFSRHSHLPLTSQYLEGLQALRSKEYLISIQKKNFLRKRLAPLAYVQSDCDPPSDRDSYVQELMKYIAVDSYGECLHNRDLPQQVNNPSSMDDSQFHHILAQYKFILAFENAVCEDYITEKLWRPLKLGAVPVYFGAPNVENWLPSNKSAIIVGRFSHPKELATYIKKLDKNDKLYMQFIEWKLHGNINNKHLLSTITERKWGVQDVTQDNYIDAFECMICKRVWENVRLKDRVSTTKLWNAESLHLNCPAPEAFSFLPGHLLKSSMREMWKPSFEQSKKEAKALRTLVDRNRNFTTVEFWNLVFKFQ
What is the function of this protein?
Probable fucosyltransferase.
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 10, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: MURC_BARQU
Sequence: MKMPFNIGLIHFVGVGGIGMSGIAEVFHNLGYKVQGSDHVDSANVERLRGKGINIQIGHHAENLGDAEVVVLSTAIKKTNPEYIAAKEKHLPIVRRAEMLAELMRFRRAIAVGGTHGKTTTTSMIAALLDAGRFDPMVINGGIINAYGTNARMGSGDWMVVEADESDGTFLKLPADIAVVTNIDREHLDHYGSFCAVREAFRQFVENVPFYGFAVLCLDHPEVQSLASRIDDRWVITYGTNPQADIRFLNLSMDGQKTHFDVFIRSRKTGKETELKNLVLPMSGQHNVSNATAAIAIAHELGISNESIKKGLAEFGGVKRRFTQTGSWRGIEIFDDYGHHPVEIKAVLYAARESAKGRVIAIVQPHRYSRLYHLFDDFAACFNDADTVLIAPIYGAGEAPIAGFGARELVEHIKMAGHRDVRLIHCLEDVVLIVSTFAKPGDYVVFLGAGNITQWAAALPHQLAVLDNNDEFSVD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEM2_SCHPO
Sequence: MDNWEDPNFELRNLRVIDLKKILHESGVSFPVNARKIEYIRMVDRIRKNKLSSGPQHLLSHLQKEENSNTSKASSSEDEIAPKYLYPSSPSKSTKKPHNETEPLLSPQFIDKPSNIETPVKIESPHVSQNNTFQSYSELSPNVETSLTMKTPPAHASTPKFRSHKSHRVAVPMSFMDSSALHTSPAFSERLKLLSSSNNFSPQLRSPKISHRLQTSATSSPLQHKRPFTNVPERVSRDIEFAPLDSARPSESSSPYSEVDSAEEDDELFQNYVLQQTRKESKLWSFIKKVFHDIKYANYRLLHNLRAFPGISAISSSYLVHIFMILLGVVAAIFLALLREKMFTAGFCDSGASGSSASILGISFPSLCRTCPPNAICPSPNYVECKPGYVLYEPWYSSLGFWPSKYCVSDTSREESVNIFREECLSVLRSWNAILHCSNNSSDLLERNMSYNAHPYVADNLNISSDHISFPSKPFALGLLHDTLLERKSPTLGLEMFEDLFKASLAVLSETNEVVMDSKLICYDSWAGIPLRCRLKQQLIKFVWRNKVFLFGILALSGVIFKLINFFRTRSIVAKYLPSASRFCVESLKRQKANYQMSRSQEPVIPLIEMHDILFHGNGPLEQIHMTKATARTLWEAIVERVEQVGSVRTRESEVDGEWTRVWEWVGTNTLDFQTDRSFINTTSPLRE
What is the function of this protein?
Nucleus inner membrane protein involved in meiosis (PubMed:20404563).  Plays a role in regulating nuclear envelope (NE) morphology and nuclear integrity, particularly during spindle pole body (SPB) extrusion or insertion through the NE, and perhaps during karyokinesis (PubMed:28242692).
What are the official names of this protein?
Lap-Emerin-Man domain protein 2, LEM domain protein 2.
Protein: MSCL_SHESA
Sequence: MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIVLQAAQGDAPAVVIAYGKFIQTIIDFTIIAFAIFMGLKAINSLKRKQEEAPKAPPAPTKDQELLSEIRDLLKAQQEK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_FRATO
Sequence: MITTRFAPSPTGFLHVGGVRTALFSWLYAKNNNGKFILRIEDTDLERSTQEAVDAILDGMSWLGLKNDGEIYYQTKRFDRYKEVIQELIADGKAYYCSCSKERLEELREYQQANNLKTGYDGKCRDANYIPQQGESYVVRFKNPQDGVVSWDDAVKGRISISNHELDDMIIQRADGSPTYNFCVVVDDIDMAITHIIRGDDHVNNTPKQINIYKALNANVPVFAHVPMILGPDGAKLSKRHGAVNVMQYREDGYLPQAILNYLVRLGWSHGDQEIFSIEEMIKAFNLEHINASPSRFDFEKLKWLNKHYIKESKFDDIQTEVEYHFAKIGLDISNGPDLKELVAVMAEKVDTLVELAEKSSYFYSDDISYDENAVKKHIKASTGEIFVKLLENFEALDAQQWQDPDVLYNIVSTTAEQCQVGMGKVGMPLRVAITSSGQSPDIGITLKLLGKNKVVARLTKALEELCK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFAT_MIMIV
Sequence: MCGISACLNHTNNSAMTSVVNALTKLQNRGYDSAGICTTSNGKFNFVKSVSDDTNNAIHYIKNNPLANHHCSIAIGHTRWATHGEKTIENAHPHFDASGRFSLIHNGIIENYDQIKSMLVESQNYQFYGQTDTEVAVAYLSYLLSENKTWFDFNESLKGSWAIIALDKFNPEKLYFMRNGSPLIIGFNETNTKAMIVSELSGFDSDISQYCIVGDNDYGYITNNNDKYIIKSQQHYQMISMGKIVMDLTPSPYKHWTQREIYDQPNAIHSLITERIVDSQLFFPEFNTINFTLVEHIVLLGCGTSYHAAQIGRRYIREFRPNITVDVIDGADFEETDIPKSRNTLLILLSQSGETKDLYRALVIGKQHSLKTIGIINVENSLIAREVDTVLYLRAGRENAVASTKSFTNQVLMLFMLALKINLSLDNSQLDYYTMSLNNFPIEFKKIIDQSVNEIPKLLEFFDNQTSCFILGKFGLEWIAKEGSLKIKEISYVHSEGYSSAALKHGPFALLHQNIPVVLLANDDSYFSKIENANSEIRSRKAKVIFITNKLIDNHCTDYLIHINTKSPLFHLLCIVPLQLLAYHLALSKGINPDYPRNLAKVVTVE
What is the function of this protein?
Controls the flux of glucose into the hexosamine pathway.  Most likely involved in regulating the availability of precursors for glycosylation of proteins (Potential).
What are the official names of this protein?
Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing], GFAT, D-fructose-6-phosphate amidotransferase, Hexosephosphate aminotransferase.
Protein: RS4_SYNP2
Sequence: MARYRGARLRITRRLGELPGLTRKSARREYPPGQHGQGRRKRSEYAIRLEEKQKLRFNYGVSEKQLIRYVRKARRTTGSTGQTILQLLEMRLDNTVFRLGMAGTIPGARQLVNHGHILVNGRVVDIPSYQCRPGDVITVRDRDRSRKLIEANMEFPGLANIPSHLEFDKPTLTGKVNGIIEREWVALQINELLVVEYYSRMA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TM234_ANOGA
Sequence: MDSPENTVPASVDIYAVLSILLVAIMWGATNPFIKRGSIGYNELKADSKLGQLWLEVRFLITRWQYLLPLVINQLGSIVYVLTLQRTELSLTVPMANSLTFVFTAITARLLGERQSGWKIYCGMTLVILGTVICGLDKML
What are the official names of this protein?
Transmembrane protein 234 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM234 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAPSD_PAMV
Sequence: MVDSKKTETPQVVDASKKAENSKTSQAGRIQFLSAPKQFSASDVRSSPSLADLDEIAYEVRTTSIASPAEIEAVCQLWIRNTEIPADKVALIAIDMARAYADVGASRKAVLLDAPTLAPTVARSRLAQLKAGAGISPRQFCSYYAKIVWNLMLHKNEPPANWAKIGFKEDYKFAAFDFFDAVDSPAALEPSQWVRHPTDKERAAHGVVKWASLSRERLQEGTSITTVAELNKGHLGGYNNLPALMAPPS
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA.
What are the official names of this protein?
Coat protein, Capsid protein, CP.
What is the protein family that this protein belongs to?
Belongs to the potexvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: KRA48_HUMAN
Sequence: MVNSCCGSVCSDQGCGQDLCQETCCCPSCCQTTCCRTTCYRPSYSVSCCCRPQCCQSVCCQPTCCRPSCCVSSCCKPQCCQSVCCQPTCCHPSCCISSCCRPSCCVSSCCKPQCCQSVCCQPNCCRPSCSISSCCRPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPACVISTCPRPVCCASSCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 4-8, Keratin-associated protein 4.8, Ultrahigh sulfur keratin-associated protein 4.8.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 4 family.
Protein: TRPB_BLOPB
Sequence: MIKLKSYFGEFGGMYVPQILIPALTQLEEAFISAQDDAIFQKELKYLLNNYAGRPTPLTLCRNLTKGTRAKLYLKREDLLHGGSHKTNQVLGQALLAKRMSKTEIIAETGAGQHGVAVSIAASLLGLKCRIYMGSKDIKRQKLNVLRMQLMGTQVIPVHRGSETLKDACNEAMREWSKTYEYTHYMLGTAAGPHPFPTIVREFQRIIGKETYKQIQKYEQCLPDAIIACVGGGSNAIGIFSDFVDIPSVQLLGVEAGGLGINTEYHGAALQHGSIGIYFGMKTSILQSSEGQVKNSYSVSAGLDFPSVGPEHVYLKNTGRVQYVSINDIEAITAFKKLSIHEGIIPALESAHALAHALKIIQKQPDKAQILVVNLSGRGDKDISTVHNALQKERDK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ATPB_SODGM
Sequence: MATGNVIQVIGAVVDVEFPQDAVPKVYNALEVENGAAKLVLEVEQQLGGGVVRCIAMGSSDGLRRGLKVTDLERAIEVPVGKATLGRIMNVLGEPVDMKGDIGEEERWSIHRPAPSYEELASSQDLLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKYVALKDTIRGFKGIMDGEYDHLPEQAFYMVGSIDEAVEKGKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FUMC_CHRVO
Sequence: MTKTVRSETDTFGPIDVPAAALWGAQTQRSLAHFRISSEKMPPELILALARVKRACAEANRGLGKLDDAKAAAIAGAADEVLAGRHDGEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGRRGPGRLVHPNDDVNLGQSSNDIFPTAMHVAAATQVKERLLPSLDLLRHALESKAEAFADVVKIGRTHLQDATPLTLGQEISGWAAQLALSEQAVRAALPMLCQLAVGGTAVGTGLNTDPSFGAAVAARLAEQSGLPFESAGNKFAALAGHEPLVFAHGALKTLAAALMKIANDIRWLASGPRSGLGELSLPENEPGSSIMPGKVNPTQCEAMTMLCCQVLGNDAALAIGAASGNFELNVFKPLIAHNFLQSARLLADGMDSLREHCVDGMEANRARIAELMARSLMLVTALNPHIGYDKAAAIAKHAHRHGTTLREAALALGHLSAEQFDAWVRPEDMV
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MICLC
Sequence: MSGSINKDPRDVIIAPVVSEKSYGLIDEGKYTFLVDPRSNKSEIKQAVERIFNVDVASVNTLNRSGKRRRTRFGWGQRKSTKRAIVTLKDGTIDIFGGPLA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HSSR_STAES
Sequence: MINCLIVDDDKKLLQYVSSHLERESIQTHTFTSGEASLDFLENKNVDIAIVDIMMSGMDGFELCQTLKDDYHIPVIMLTARDALSDKERAFLSGTDDYVTKPFEVKELLFRIKAVLRRYQINADNELQLGNLILNQSYMEITVGSKTMNLPNKEFQLLFLLASNPKHIFTRDDIIGKIWGFDYEGDDRTVDVHIKRLRQRLSKLKSSVSIQTVRGQGYRVDQNV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQB4_CAEEL
Sequence: MCRVFTYIHTSAVRLSALGASRESTFFKSRTALIHTVNVANFHVSRQNCRRCLDASRHCFSTRSRTEERLLLQLSIPFLHQISPKPACPPSSLNSHSFECCSLTFSYSYMMVSCKLLLYYGTFSSIISIVLSCVATSPTGTVTTTVAPTTTTAATGCTSCTASQVTFAQSGGGVQIDTAGIPGTAAGCLTLTLTCTAGTGNYAFMQFNNNQGGPAENQDMGMTINALANCVDGNWVYTSGGVSRIVTQVSCNQAPNAG
What are the official names of this protein?
Uncharacterized protein C30G12.4.
Protein: KATG_BURM1
Sequence: MSTEPKCPFHHTAGSGTSNKDWWPNQINLNILHRHSSLSDPMDKDFNYAEAFKQLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRIADGRGGAGGGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRNISWADLLILTGNVALESMGFKTFGYAGGRPDTWEPDDVYWGSEKIWLELSGGPNSRYSGNRELENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASSVGPEPEAAALEQQGLGWQSTFGTGKGKDAITSGLEVTWTSTPTKWSNDFFKHLFSYEWELTKSPAGAHQWVAKDAEAVIPDAFDPSKKHRPTMLTTDLALRFDPEYEKISRRFYEHPDQFADAFARAWFKLTHRDMGPRSRYLGPDVPAEELLWQDPVPAVDHPLIDEADIAALKAKVLASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEVNRPAELAAVLETLEGVRKAFNDAQTGGKRVSLADLIVLAGAAGVEQAAKNAGVAVTVPFAPGRTDASQEQTDVHAMAVLEPVADGFRNYLKRKFKTPAEALLVDKAQLLTLTAPEMTVLVGGMRVLGTNVGDPKHGVFTERPGTLTNDFFVNLLDMRTEWKPASADNDVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQQKFVHDFVAAWNKVMNLDRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NU4C2_TRIV2
Sequence: MMADGFPWLTAIILLPLVASAFIPLLPDKEGKLVRWYALGVGIADFVLMCYTFWHHYDASSATFQLVEKYDWVPQIGFSWAVSVDGISMPLVLLAGFVTTLSMLAAWQVNLKPRLFYFLMLVLYSAQIGVFVAQDLLLFFIMWELELVPVYLLVSIWGGQKRRYAATKFLLYTAAASIFILIAGLAMALHGDNTTFDIVELGAKNYPLALELLLYAGLLIAFGVKLAIFPLHTWLPDAHGEASAPVSMILAGVLLKMGGYGLIRLNLELLPDAHIYFAPVLATLGVINIIYGGLNSFAQTHMKRRLAYSSVSHMGFVLLGIASFTDVGVSGAMLQMLSHGLIAAVLFFLAGVTYDRTHTMAMDNLGGIGQAMPKVFALFTAGTMASLALPGMSGFVSELKVFIGVTTSDIYSPTFCTVMVFLAAVGVILTPIYLLSMLRQVFYGTGAELSCNINNGAYENQEDEGTACFGTDCLLPGEAVYRDASIREVFIAASFLVLIIGVGVYPKIATQLYDVKTVAVNTQVRQSYTQIAQSNPQIYAKGFFAPKIVEPEVMAVSGMIK
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4 2, NAD(P)H dehydrogenase I, chain 4 2, NDH-1, chain 4 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: Y1910_MESM1
Sequence: MAGHSKWANIKHRKGAQDAARSKIFMKLSKEIFVAASGPGGADPETNPSLRLAVSKAKAQSMPKANIEKALSKASGNSKNASEFKELIYSGSLPGGAIILVICLTDNLNRAISNIKAAFSKIGGQLGKSGSIPYIFERKGVLDILKEEYENSDQLMLEALDAGAEDVQTFEDFSRIITNPSNFQEVKDKIDKALSLENYATAEIQYLPNTTVSFEKEKLEKLETWIETLEDNEDVQEIYHNIDF
What are the official names of this protein?
Probable transcriptional regulatory protein MMOB1910.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
Protein: GCR_SAISC
Sequence: MDSKESLTPGKEENPSSVLTQERGNVMDFCKILRGGATLKVSVSSTSLAAASQSDSKQQRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLQLLEESIANLNRSTSVPENPKSSASSSVSAAPKEKEFPKTHSDVSSEQQNLKGQTGTNGGNVKLYTADQSTFDILQDLEFSSGSPGKETNQSPWKSDLLIDENCLLSPLAGEEDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSSSNVTLPQVKTEKEDFIELCTPGVIKQEKLSTVYCQASFPGANIIGNKMSAISIHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIIKGIQQATTGVSQETSENPANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSTVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASSNLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQLPKYSNGNIKKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC) (PubMed:10775802, PubMed:11703081).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors (PubMed:10775802, PubMed:11703081, PubMed:15857751).  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling (By similarity).  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (By similarity).  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth (By similarity).  Mediates glucocorticoid-induced apoptosis (By similarity).  Promotes accurate chromosome segregation during mitosis (By similarity).  May act as a tumor suppressor (By similarity).  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression (By similarity).
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (PubMed:15857751). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: Y1288_STRPN
Sequence: MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SP_1288.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RS5_GLUOX
Sequence: MAREPREGGRGGREREQGDDLVDKLVTINRVAKVVKGGRRFAFAALVVVGDQKGRVGYGAGKAREVPEAIRKATERAKRTMIRVPMKEGRTLHHDTFGHYGAGKVVVRAAEAGTGIIAGGPMRAVFESLGVNDVVAKSLGTRNPHNMIKATFAALEKASSPRHVASRRGKKAAELFGKREQGQTEAEVTNG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RNH1_MOUSE
Sequence: MRWLLPLSRTVTLAVVRLRRGICGLGMFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHEQKSQAKTSKRPREPLGEGEELPEPGPKHTRQDTEPAAVVSKDTFSYMGESVIVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIMQAKAQNISKLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVINKEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSED
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.  Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II.
What are the official names of this protein?
Ribonuclease H1, RNase H1.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3AR_HUMAN
Sequence: MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
What is the function of this protein?
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a.  This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
What are the official names of this protein?
C3a anaphylatoxin chemotactic receptor, C3AR, C3a-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1742_COXBU
Sequence: MFSLTQKIGFNAEKTACRYLQKQGLSFITKNFRYKQGEIDLIMSDQSMLVFIEVRYRRFSDFIHPVATVTPLKQRRLIKTALHYLQKHRPLDKISCRFDIVGITADRQITWIKNAIEVEY
What are the official names of this protein?
UPF0102 protein CBU_1742.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RL9_HELAH
Sequence: MKVLLLEDVKNLGKAGEVCEVKDGYGNNFLIANKKAKLATNEVINKYKAEVKKKAETEALEKAQKLQMAETLQTVTLTIHKKVGANGSLFGAITKEEITERLKEHHANLNLDKKDIELKHPIKSTGIYEIEVKLGSGIVGVFKIDVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ASI4B_DANRE
Sequence: MPIEFVCKIKFAEGEEAKGASTEGGGTGMLDEGLRRQKEGMADLASFASSSSLHGLARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSEDFSVVYTRYGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACRLHCESTQVQRECNCRMVHMPGDADICAPSKIKCVDKALASLQKSTGDSCPCETPCNLTRYGKELSMVKIPSRGSARYLSRKYQKSEEYIRDNFLILDIFFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYIYEVAKNKIKQLLKPKKSQKQTNQRNLIQEQIQRTKNLREQNLKAQLTAGAIATVRFEEVKVKAANDVAQPHSAHPTSVLPNHHNAQQAVQQDFAC
What is the function of this protein?
Probable cation channel with high affinity for sodium.
What are the official names of this protein?
Acid-sensing ion channel 4-B, ASIC4-B, Acid-sensing ion channel 4.2, Amiloride-sensitive cation channel 4-B, ZASIC4.2.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATB_HERAR
Sequence: MIDIAFSKLAIIGVAALVFIGPEKLPTVARMAGTLFGRAQRYINDVKSEVSREMELDELRKMHKDVQDAATDVERSIAQNISAADSSLHSAWDESDTDTNPLMEPPTLDQSSDKSKNFRKKKLAATSAVPSWYKRQSGQKSRVISGAARMAKFRPASARKSTPFFH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FER_METTL
Sequence: SVTIDYDKCKGPECAECVNACPMEVFEIQGDKVVVAKEDDCTFCMVCVDVCPTDAITVKE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons probably in the CO-dehydrogenase complex.
What are the official names of this protein?
Ferredoxin.