PharMolix/UniProtQA huggingface dataset:
Protein: SCX3_LEIQU
Sequence: VRDAYIAKNYNCVYECFRDSYCNDLCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVPGKCH
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This contractive toxin is highly toxic both to mammals and insects.
What are the official names of this protein?
Alpha-insect toxin Lqq3, Lqq III, LqqIII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1483_METJA
Sequence: MINMDKTLSVIVFLISLIIIFGIYFSSSNFSFKKVEINKSTINDFGDENILTFVPEVCDRFYYEKDGFDWERNINNIETVIIGSDAVVIEKGDFNETEILKELIENGYSVESCRGVYYYKNEKALSDRYIIVGNNLIIKANDISGIRWRYLQ
What are the official names of this protein?
Uncharacterized protein MJ1483.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PTLCB_LACCA
Sequence: MNKVFDKLKPVFEAIAANKYISAIRDGFIACMPIIIFSSIFMMVAYVPNAWGFYWPDNVTNTLMVAYNYSMGLLALFVAGTTAKNLTDSKNLELPKTNQINPVAVIVASEISFVILSILPLKTGVDLTYMGTQGLICAYIVGLIVPNIYYVCIKNNVTIKLPEQVPGNIAQSFKDLIPMGLSVTAFWLFGVGFKAATGTVLPRWIIQVLSPLFQASDSYLGLALIAGAMAFFWFCGVQGPSIVQPAVVPIMIANTAANLQQYQAGQHVSHVLAMNTMDYVMNFGGTGATLVVPFIMLFAARSAQLKAVGKAAFVPCTFGVNEPVLFGMPIIMNPMLFIPFLATPIVNVCLFKFFVSVLGMNSMMYTMPWTVPGPIGILISTGFAPLAFVFVLLTLVLDVAIYFPFIRVYDSTLLAEEKAKEEVIEDDGMAVLASDTVSPSIPTGLTVATATDDDATHVLPETAPSAHGEAYFKQNEVDVLVLCAGGGTSGILANALNKLSKERGLKLSAAARAYGQDMDLIKDMNMVILAPQMESMKGNLKKITDKYGVKLVTTTGRQYIELTNNGDMALDFVESNL
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIICB component, EIICB-Lac, EII-Lac.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_STRT1
Sequence: MANRLKEKYTNEVIPALTEQFNYSSVMAVPKVDKIVINMGVGEAVNNAKTLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDNVDKVRGMDIVIVTTANTDEEGRELLKGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CONOI_CONVL
Sequence: EPNSIWS
What is the function of this protein?
May act as a neurotoxin.
What are the official names of this protein?
Conophan vil-I'/vil-I'(O2P).
What is the protein family that this protein belongs to?
Belongs to the conophan family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRP_ECO57
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: ISPDF_CAMJ8
Sequence: MSEISLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSSNITYMKKFTKNYEFIEGGDTRAESLKKALELIDSEFVMVSDVARVLVSKNLFDRLIENLDKADCITPALKVADTTLFDNEALQREKIKLIQTPQISKTKLLKKALDQNLEFTDDSTAIAAMGGKIWFVEGEENARKLTFKEDLKKLDLPTPSFEIFTGNGFDVHEFGENRPLLLAGVQIHPTMGLKAHSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREVGFELINIDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVNLKYFDWTRL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: RNS1B_PYGNE
Sequence: MALDKSVIPLPLLVVVLLVLGWAQPSLGGESQAEKFQRQHMDSGSSPSSSSTYCNQMMKLRNMTQGWCKSVNTFVHEPLVDVQNVCFQEKVTCKNGQTNCFKSNSKMHITECRLTNGSKYPNCAYQTSPKERHIIVACEGSPYVPVHFDDSVEDST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Compared to RNASE1 it has lost activity towards dsRNA.
What are the official names of this protein?
Ribonuclease 1B pancreatic, RNase 1B.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMA3_BACFR
Sequence: MKESKKRVLVGMSGGIDSTATCLMLQEQGYEIVGVTMRVWGDEPQDARELAARMGIEHYVADERVPFKDTIVKNFIDEYRQGRTPNPCVMCNPLFKFRMLIEWADKLGCDWIATGHYSRLEERNGHIYIVAGDDDKKDQSYFLWRLGQDVLRRCIFPLGNYTKQTVRDYLHEKGYEAKSKEGESMEVCFIKGDYRDFLREQCPELDAEVGPGWFVSSEGVKLGQHKGFPYYTIGQRKGLEIALGKPAYVLKINPQKNTVMLGDAGQLKAEYMVAEQDNIVDEDELFACPDLAVRIRYRSRPIPCRVKRLEDGHLLVRFLAEASAIAPGQSAVFYEGRRVLGGAFIASQRGIGLVIEQNKDWK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 3.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC10_DROME
Sequence: MAASMDEDITANPPPSSEEDPLAEERLGFVREVGAQAVWSLSSCKPGFGVERLRDNIMDTYWQSDGQLPHLVNIQFHKRTNISQIYIYTDYKLDESYTPSRISIRSGTNFNDLQELQVMDLTEPTGWVQIPIKDGNVKSIRTFMLQIAVISNHQNGRDTHMRQIRIHAPVEGKHYPLELFGKFGTVDFQKFATIR
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 10, APC10, Cyclosome subunit 10.
What is the protein family that this protein belongs to?
Belongs to the APC10 family.
Protein: ATG1_KLUMD
Sequence: MSSESHGKAVAKAIRLPTENYTVEKEIGKGSFAIVYKGVSLRDGRNIAIKAVSRSKLKNKKLLENLEVEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFFIKKRRSLVMKHPLIKTVFDLYPPPSAEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLQDYSDPKTFHEMGFIGIYNLPVLKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEVTVPSNCYIEPKIFKLIKGLLTFDPEARMGFNEFFNNEVVTEDLSRYEASYEPDLESKSKDVAESNMFVSEYLVRPAAQEKANGGLRTDEGSAMPGAEHTYNKEREHYRERQDLQGQQQQQQQHPDSPPRGSTQGYQSSAGQTRMKSSYNDLILEKEYVVVEKKTVEVNSLADDFANNGPTTNNQGAQIIKPLRYRTSSSSDGHGGRRASLVERRLSISSLSPSNALSKALGLASVRLFGYQQPNTQTTSTSTHPTLLNPQIFHELTENAVLRADHHLNLFNEQISDSNITPFVESLSAKAFVMYSFAEMKFSQILPSPPSSTDYYSQSDKRLSNGSCAIDDDDDLDSGNPSSNQTLTPGANKVSAANVDNLIPAPELKKLCMESLLLYLKSLTILASSMKLTSKWWYENESKNCTLKLNILVQWIRDRFNECLDKAEFLRLKLHTLNQSEDPQVLDDEPTIFVEKLIYDRALDISRNAARLEMEGGNYNTCELAYATSLWMLEILLDEHLSSNEVYDDGYSSNITSLDESDKEMIRKYVSSIANRLKALKSKMS
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes (By similarity).  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates (By similarity).  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: CWC22_SCHPO
Sequence: MEKEDKSFGIGMLDYNRENPESSGHSRVAVIRKQKTEQENNNLSWEDRHYIPDLHKSNKIKTPTSLADEKKSHNELDPKAQIKKLMETRSGGTYIPPAKLKALQAQLTDVNTPEYQRMQWEALKKSINGLINKVNKSNIRDIIPELFQENIIRGRALYCRSIMKAQAASLPFTPIYAAMTAVINTKFPQIGELLLTRLIVQFRKSFQRNDKSMCISSSSFIAHLINQKIAHEIVGLQILAVLLERPTNDSIEIAVMLLREIGAYLAEVSTRAYNGVFERFRTILHEGQLERRTQFIIEVLFQTRKDKFKNNPTIPQELDLVEEEDQITHYISLDDNLDVQESLGIFHYDPDYEENEKKYDAIKHEILGEEDDDENEEDEEDSEETSESEEDESVNDEKPQVIDQTNASLVNLRKSIYLTIMSSVDFEECCHKLLKIDLPEGQEIELCNMVIECNSQERTYAKFYGLIGERFCKLSRTWRSTYEQCFKNYYETIHRYETNRLRNIALFFANLLSTDSIGWEVYDCVRLTEDDTTASSRIFLKIMFQEIVEALGLKSLVERLHDPNLVPYLHGLFPVDEARNVRFSINYFTSIGLGALTEEMREYLLTMPKSEPKEQDSEGYSSGSETGSTYSSSYSSTYSRGRSYSRSTRSYSKSRSYSRSRSVTPINNINHKKYIRKDRELSPRGRERSSNRNSYSDLSRSSSLSRGRSRSYTPEGRLIESEDKGYRSRSSSPASRKYRSRQRYRRSYAGSTSRGRSFSRSPSYRRRLSMSCSVSYSRSPSPAARPISRSPARNKRSYDSLSYNRQYSPKVSRKRSNESRSPSPYTLRKQKTYHLNKRNEDFVVKMDKKGSESPVILAPWLREVDDGELYKDRNSESDSVRKQPRAD
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor cwf22, Complexed with cdc5 protein 22.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSBA_PORPU
Sequence: MTATLQRRESASLWERFCSWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFVAAPPVDIDGIREPVAGSLLYGNNIISGAVIPSSAAIGIHFYPIWEAASLDEWLYNGGPYQLVVLHFLTGVACYIGREWELSYRLGMRPWISVAFTAPVAAAAAVFLVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGSLFSAMHGSLVTSSLIRETSENESANYAYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGLWPVVGIWLTALSVSTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASGESLPVALTAPAVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LGT_BORPE
Sequence: MLQYPQIDPVALRIGPLAIHWYGLMYLIGFALVYAFGRRRITSGHTTSMTVRDLEDLIFYSVLGVVLGGRLGYVLFYKPAHYLANPLEIFYLWEGGMSFHGGLIGVIVVMLLFAHKKRLGFFTVSDFIAPLIPLGLAAGRLGNFINGELWGRPTDVPWAMIFPQSGDGLPRHPSQLYELGLEGIVLFALLWWYSSKPRAAGQVSAMFLMGYGAFRFLVEFTREPDNFLGLLAAGLSMGQWLSIPMVLAGAGLYLFTARPPSR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_SHIBS
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PSB2_SULIN
Sequence: MVIMGNKLQLENKILKGTTTVGIKVNDGVVLAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNNITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKV
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_CLOD6
Sequence: MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACETTVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGDIAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRLTEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHVIKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSEEKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRKDALGE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB27G_ARATH
Sequence: MGTSSSSSGLVKAKSETLAEALKSSSLDFSNGDGSSHGSKQHVRARTLSSPSYSSNSKNRWNTHIRKAKSAHPALDLAGLTGGAALSRASSASLGLSFSFTGFTVPHEEIIASERCSNDDILEDIEAATSSVVKFQAEPTFPIYLKFIDITYKVTTKGMTSSSEKSILNGISGSAYPGELLALMGPSGSGKTTLLNALGGRFNQQNIGGSVSYNDKPYSKHLKTRIGFVTQDDVLFPHLTVKETLTYTALLRLPKTLTEQEKEQRAASVIQELGLERCQDTMIGGSFVRGVSGGERKRVCIGNEIMTNPSLLLLDEPTSSLDSTTALKIVQMLHCIAKAGKTIVTTIHQPSSRLFHRFDKLVVLSRGSLLYFGKASEAMSYFSSIGCSPLLAMNPAEFLLDLVNGNMNDISVPSALKEKMKIIRLELYVRNVKCDVETQYLEEAYKTQIAVMEKMKLMAPVPLDEEVKLMITCPKREWGLSWWEQYCLLSLRGIKERRHDYFSWLRVTQVLSTAIILGLLWWQSDITSQRPTRSGLLFFIAVFWGFFPVFTAIFTFPQERAMLSKERESNMYRLSAYFVARTTSDLPLDLILPVLFLVVVYFMAGLRLRAESFFLSVLTVFLCIVAAQGLGLAIGASLMDLKKATTLASVTVMTFMLAGGYFVKKVPFFIAWIRFMSFNYHTYKLLVKVQYEEIMESVNGEEIESGLKEVSALVAMIIGYRLVAYFSLRRMKLHSST
What are the official names of this protein?
ABC transporter G family member 27, ABC transporter ABCG.27, AtABCG27, Probable white-brown complex homolog protein 28, AtWBC28.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM0_CHICK
Sequence: MAAFLRCPLLARHPPLARAFATGARCPFMGFAHRAAPELQEDVERPQIPAVEVLEELLRDGGAALNRTVRDCMDEDAFPYEEQFQAQLGALRRTHTYRVVTAVGRRADAPPLGTRGTAPHTSVELWCSSDYLGLSRHPAVLRAARAALDAHGLGAGGTRNIGGTSPLHGALERALALLHRQPRAALFSSCFAANDTALDTLARILPGCQVYSDAGNHASMIQGIRRRGVPKFIFRHNDPHHLEQLLGRSPPGVPKIVAFESLHSMDGSIAPLEELCDVAHAYGALTFVDEVHAVGLYGARGAGIAERDGVQHKVDVVSGTLGKALGAVGGYIAGSEALVDAVRSLGPGFIFTTALPPQRGGGALAALQVVGSAEGAALRRAHQRHAKHLRVLLRDRGLPALPSHIVPVRWDAEANTRLSRALLEEHGLYVQAINHPTVPRGQELLLRIAPTPHHSPPMLENLADKLSECWGAVGLPREDPPGPSCSSCHRPLHLSLLSPLERDQFGVRGAAAG
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (By similarity).  Contributes significantly to heme formation during erythropoiesis (By similarity).
What are the official names of this protein?
5-aminolevulinate synthase, erythroid-specific, mitochondrial, ALAS-E, 5-aminolevulinic acid synthase 2, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: DDI1_ARATH
Sequence: MRITVMTAGEQIITLDVDSQETVENVKALLEVESNVPIQQQQLLYNGNEMGNSDKLSALGVKDDDLLMMMVSNASSGSATSAAGNDLGMNPDGSALNPAAFQQHIRGDSNLMGQLFQNDPELAQVISGSDLNKLQDVLRARHRQRSVLQRQKEEELALLYADPFDVEAQRKIEAAIRQKGIDENWEAALEHNPEGFARVIMLYVDMEVNGVPLKAFVDSGAQSTIISKSCAERCGLLRLMDQRYKGIAHGVGQTEILGRIHVAPIKIGNNFYPCSFVVLDSPNMEFLFGLDMLRKHQCTIDLKENVMTVGGGEVSVPFLQEKDIPSRFLDEERVPNDASSSGATVPSGFTEKKNNTVANPTSQQPKRQNTSEGPEFEAKIAKLVELGFSRDSVIQALKLFEGNEEQAAGFLFGG
What is the function of this protein?
Receptor of ubiquitinated protein targeted to ubiquitin/proteasome-mediated proteolysis (UPP).  Relatively weak affinity for both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains with a slight preference for 'Lys-48-'linked chains of three or more ubiquitin units.
What are the official names of this protein?
Protein DNA-DAMAGE INDUCIBLE 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RECA_ECOBW
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CAUSK
Sequence: MKFLDQCKIYVRSGNGGGGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRGRHGAAGDDVLLKVPVGTQVLEEDKETLIADLDTAGMTLRLAKGGNGGWGNLHFKGPVNQAPKYANPGQDGEELWVWLRLKLIADVGLVGLPNAGKSTFLAAATAARPKIADYPFTTLTPNLGVVDLSTSERFVLADIPGLIEGASEGAGLGTRFLGHVERSAVLIHLVDATQDDIAGAWTTIRGELEAYGDELADKSEILALNKVDALDPETRKAKAAELQAVSGIKPMLVSGVSGEGVTELLRAAFTQVRIRRGETPAEAAIDEAPEEETPGGWQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_PARD8
Sequence: MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGDSEYRFGIESVSKVHTAILVLRQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVNAGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDELYKSESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITSMISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAIKYVMNKLGLNVFNGHRVTIVD
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: MUTB_PORGI
Sequence: MKPNYKDIDIKSAGFVAKDATRWAEEKGIVADWRTPEQIMVKPLYTKDDLEGMEHLDYVSGLPPFLRGPYSGMYPMRPWTIRQYAGFSTAEESNAFYRRNLASGQKGLSVAFDLATHRGYDADHSRVVGDVGKAGVSICSLEDMKVLFDGIPLSKMSVSMTMNGAVLPILAFYINAGLEQGAKLEEMAGTIQNDILKEFMVRNTYIYPPEFSMRIIADIFEYTSQNMPKFNSISISGYHMQEAGATADIEMAYTLADGMQYLKAGIDAGIDVDAFAPRLSFFWAIGVNHFMEIAKMRAARLLWAKIVKSFGAKNPKSLALRTHSQTSGWSLTEQDPFNNVGRTCIEAMAAALGHTQSLHTNALDEAIALPTDFSARIARNTQIYIQEETLVCKEIDPWGGSYYVESLTNELVHKAWTLIKEVQEMGGMAKAIETGLPKLRIEEAAARTQARIDSHQQVIVGVNKYRLPKEDPIDILEIDNTAVRKQQIERLNDLRSHRDEKAVQEALEAITKCVETKEGNLLDLAVKAAGLRASLGEISDACEKVVGRYKAVIRTISGVYSSESGEDKDFAHAKELAEKFAKKEGRQPRIMIAKMGQDGHDRGAKVVATGYADCGFDVDMGPLFQTPEEAARQAVENDVHVMGVSSLAAGHKTLIPQVIAELEKLGRPDILVTAGGVIPAQDYDFLYQAGVAAIFGPGTPVAYSAAKVLEILLEE
What is the function of this protein?
Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
What are the official names of this protein?
Methylmalonyl-CoA mutase large subunit, MCM-alpha.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
Protein: NEUR_DROME
Sequence: MGLSDIPANYMQGSHPHLTLHPQQQHHQNQQHLQHLQQMQQLHNAMPTPAQQAAQVLAMESNELLMSTKDKLSSKKKMHLLKKIKKRFGLVRRSPSSCPGPNNLPPLQFHSVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEISNNWNGGIRFGFTSNDPVTLEGTLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDVIYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPSLQSLHLAGNGGSVASVEQAAIAHDLANGLPPLRYNANGRLIPVPFHNTKGRNVRLSQDRFVASRTESDFCQGYVFTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVSKDIAAAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLPNMVAYPSQPQVNVNASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLASAGGVNGSRMISMPSNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACSSGTLISTTSSQYIEQPIANSTNNAANKWKDSLSDQQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVGGGQCPLCRAVIRDVIRTYTT
What is the function of this protein?
Involved in neurogenesis.  Interacts with other neurogenic proteins in the specification of the neuroblast versus epidermoblast cell fate.
What are the official names of this protein?
Protein neuralized.
What are the subcellular locations of this protein?
Nucleus.