PharMolix/UniProtQA huggingface dataset:
Protein: LPXK_XANOM
Sequence: MSKRGARTPGFWYDNNTPIPLPARILVPVYGAAIALRRALYRRGWRKRHGVPVPVIVVGNVTAGGTGKTPLTIALVAKLQEAGWTPGVASRGYGRDEAGKARWVEADTPVALGGDEPVLIAWKTGARVRVDSDRLAAARALVEAGCDIVICDDGLQHYRLARDVEIEVVDGQRRYGNGRLLPAGPLREPVARARDCDFRVVNLGQASTTAAPQAPDDAGFGEWQMRLSIDSVQPMDGKRAQPLSMLAGQRVHAVAGIAYPERFFAMLRARGIGVVPHAFPDHHVYRAADFSFGSRLPVLMTEKDAVKCRPFADEWLYSVPLKAELPAAFWVSLLDRLNKLASRQGV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: AUGN_HUMAN
Sequence: MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHGASVNYDDY
What is the function of this protein?
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity).  ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).
What are the official names of this protein?
Augurin, Esophageal cancer-related gene 4 protein, ECRG4.
What is the protein family that this protein belongs to?
Belongs to the augurin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Apical cell membrane.
Protein: Y1128_XANC5
Sequence: MRGNIAQLMQQAQKMQENLQRAQEELAKLEVTGSAGGGMVSVTLTGAKECRKVRIDPSILSDQEMAEDLIAAAFNDASNKIDAESKDRMGSATAGMQLPPGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein XCV1128.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DPOL_HBVD5
Sequence: MPLSYQHFRKLLLLDNEAGPLEEELPRLADEDLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSSVPVFNPHWKTPSFPNIHLHQDIIKKCEQFVGPLTVNEKRRLKLIMPARFYPNFTKYLPLDKGIKPYYPEHLVNHYFHTRHYLHTLWKAGILYKRVSTHSASFCGSPYSWEQELQHGAESFHQQSSGILSRPSVGSSLQSKHQQSRLGLQSQQGHLARRQQGRSWSIRTRVHPTARRPSGVEPSGSGHNANLASKSASCLYQSTVRTAAYPAVSTSENHSSSGHAVELHNLPPNSARSQSERPVSPCWWLQFRNSKPCSDYCLSHIVNLLEDWGPCAEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGNYRVSWPKFAVPNLQSLTNLLSSNLCWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRIINHQHGTLQNLHDSCSRNLYVSLLLLYKTFGWKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGSLPQDHIRHKIKECFRKLPVHRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLNLYPVARQRPGLCQVFADATPTGWGLVMGHQRMRGTFSAPLPIHTAELLAACFARSRSGANILGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGPCRPLLHLPFRPTTGRTSLYADSPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: NLPI_SALTI
Sequence: MKPFLRWCFVATALTLAGCSNSAWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPYRSLWLYLVEQKLNEKQAKEALKARFEKSDKEQWGWNIVEFYLGDISEATLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
What is the function of this protein?
May be involved in cell division.  May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity).
What are the official names of this protein?
Lipoprotein NlpI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL18_SHIB3
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CANB2_DROME
Sequence: MGNETSLPMEMCSNFDADEIRRLGKRFRKLDLDNSGALSVDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIGFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV
What is the function of this protein?
Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium-dependent, calmodulin-stimulated protein phosphatase.
What are the official names of this protein?
Calcineurin subunit B type 2, Protein phosphatase 2B regulatory subunit 2, dCNB2.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: RPOZ_THESQ
Sequence: MEKIVKFDLKYDELLKKIPYKYAIPVVVAKRAEAIREYARPFVITDDENYVSIAFMELSLNYIRIKNEEILKALIPKVK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: UCRI_RICBR
Sequence: MSDTEDTNNDNKVEFEDRSKTSRRDFMVLTASSVAAVGAACTLWPLINSLNPSADVLALSSIEVDLSNIAVGQTVTVKWQGKPVFITNRTPDKIAEARAVKMSELIDPEEDQDRVKAGHDNWLVTIGICTHLGCVPLANQGDYDGWFCPCHGSQYDSSGRVRRGPAPLNLAVPPYTFISDKKIRIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRMD_LACH4
Sequence: MKINVLTLFPDMFTPLQVSMLGRGLEDGKWDLNLVNFRDFTTDVHHHVDDTPYGGGAGMVLQIMPIKKALDSLPSTGKVIITAPQGKTFNEQMAQDWAKEDELTFICGHYEGFDQRVYDLADETVSIGDYVLTGGELPTMSMIDATVRLLPGILGNAASPVEESFSHGLLEYPQYTRPADFEGQKVPEVLTSGNHQKIAEWRHKEALKATYLHRPDMLEDRQLTNEEKKMLEEIKSELD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_PSYA2
Sequence: MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGMGIKIQKQGDTVTCDTKSIDNFYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFSFDMVTVGGTENVIMAAALAKGTTVLGNCALEPEVVDLANMLVAMGAKISGIGTAIMTIEGVERLHGCEYAVVPDRIETGSYLAGALMTGGDVLTKNTSALLLTPVLEKFEDMGAIITSGDDWIRAQMKGRPKAVDIRTQPHPGFPTDMQAQVMAIACLADGTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVECFTAAPVMATDLRASMSLVMAAAAAEGESLIDRIYHIDRGYEHVEKKLRALGVNIERINSND
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPD_RAT
Sequence: MPENVASRSGPPAAGPGNRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDIEREDIEFICKTIGTKPVAHIDQFTPDMLGSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein: PRX2_POPTR
Sequence: MAPIAVGDVLPDGKLAYFDEQDQLQEVSVHSLVAGKKVILFGVPGAFTPTCSLKHVPGFIEKAGELKSKGVTEILCISVNDPFVMKAWAKSYPENKHVKFLADGSATYTHALGLELNLQEKGLGTRSRRFALLVDDLKVKAANIEGGGEFTVSSADDILKDL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin-2, Prx, 1-Cys D-peroxiredoxin, Glutaredoxin-dependent peroxiredoxin, Peroxiredoxin II, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
Protein: UBIG_VIBC1
Sequence: MTKAQNVDPSEIKKFEEMASRWWDLEGEFKPLHQINPLRLNYVLEKADGVFGKKVLDVGCGGGILAESMAKEGAVVTGLDMGKEPLEVARLHALEAGTKLTYIQSTIEDHAAENAGTYDVVTCMEMLEHVPDPLSVIRSCAALVKPSGHVFFSTLNRNMKSYLFAIVGAEKLLRIVPEGTHDHEKFIKPAEMMKMIDQTDLTEMGITGLHYNPLNDSYKLGRNVDVNYIVHTTKY
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: HGPRT_STRR6
Sequence: MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKGSIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDIIDTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDYKENYRNLPYIGVLKEEVYSN
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PORGI
Sequence: MDRQFKRTLITTALPYANGPVHIGHLAGVYVPADIYARYLRLRGRDCLLIGGSDEHGVPIALKAKAEGCTPQEVVDRYHELIKRSFEGLGISFDIYSRTTSDIHRRTASEFFKTLYEKGEFVEQTSEQYYDEEAKQFLADRYIIGTCPHCSNDRAYGDQCEACGTSLNATDLIDPRSTISGSAPVLRETKHWYLPLDKHEPFLKEWILDGHKEWKSNVYGQCKSWLDMGLQPRAVSRDLDWGIPVPVEGAEGKVLYVWFDAPIGYISNTKELCPDSWETWWKSEDTRLVHFIGKDNIVFHCIVFPAMLRAEGSFILPDNVPANEFLNLEGDKISTSRNWAVWLHEYLEEFPGKQDVLRYVLTANAPETKDNDFTWRDFQARNNNELVAIFGNFVNRALVLTHKYFDGAVPPKGELTDCDSRTIEEFAAVKQALEHQLDTFHFREALKEAMNLARIGNKYLADTEPWKLAKTDMNRVATILNLSLQITANLAIAFEPFLPFSSAKLMSMLSTDCPFGWDRLGSTDLLPEGHVLGNPELLFEKLEDSVIDAQIQKLQDTKLANEKAAHQAAPIAEDIAFEDFLKLDIRVGTVLECEKVPKADKLLRFRIDDGLSGRTIVSGIAKHYAPEELVGKQVCFIANLPPRKLKGIESEGMILSAEDADGSLRVIMPAAEVAAGSQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_GEOSL
Sequence: MQRIIPIDSPFFLNPDELGTPADWTAVFGNDNPLALEIGCGIGDFIARTALDHPTTNFIAIDYYNKGCLKTCSRLERHGITNVRVVRAEARQFIVERIQKGSLAAVYINCPDPWPKKRHRKRRLVNTQFVRFIRDYLAPGGDFYFATDFDDYGEDVAAFMPQMPGYANMLAPDIFRHELEGYHLSKYMQKFMAEGKRIYFIHYRTTMEG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TATA_RHOPA
Sequence: MGSLSIWHWIVVIAVVLLLFGRGKISDLMGDVAQGIKSFKKGLQDDEKTAEKSEPVKSIDHTSTPGATNRTDVGSKAV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DAF_PONPY
Sequence: VPNAQPALEGRTSFPEDTVVTYKCEESFMKIPGKKDSVICLKGSQWSDIEEFCNRSCEVPTRLNFASLKQPYITQNYFPVGTTVEYVCRPGYRRELSLSTKLTCLQNLTWSTAVEFCKKKSCPNPGEIRNGQIDVSNGILFGATISFSCNTGYKLFGPTSSLCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGKRDHYGYRQSITYACNKGYTMIGEHSIYCTVNDDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTSLLSGHKCFTLTGLLGTLVTMGLLT
What is the function of this protein?
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation.  Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.  Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.
What are the official names of this protein?
Complement decay-accelerating factor.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: UXAC_SALPA
Sequence: MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITSTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSINIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: MURB_SALTI
Sequence: MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRDSIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADIAMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNVWLEPEVRFIGQFGEVNAVESIA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SHEPA
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIIASKMIHLSKEQAEGFYAEHSERPFFGALVAFMTSGPIMVQTLEGENAVLAHREILGATNPAEAAEGTIRADFAESIDENAAHGSDSVASAEREVAYFFSAEELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_HPV03
Sequence: MAGIFIYGLSPSFCPDVVAVNVSHIFLQMALWRSSDNLVYLPPTPVSKVLSTDDYVTRTNIYYYAGSSRLLTVGHPYFAIPKSSNSKMDIPKVSAFQYRVFRVRLPDPNKFGLPDARIYNPDAERLVWACTGVEVGRGLPLGVGLSGHPLYNKLDDTENSNIAHGDIGKDSRDNISVDNKQTQLCIVGCTPPMGEHWGKGTPCKQNASPGDCPPLELITAPIQDGDMVDTGYGAMDFGNLQSNKSDVPLDICQTTCKYPDYLGMAAEPYGDSMFFYLRKEQLFARHFLNRAGMAGDTVPDALYIKGDSQSGGRDKIGSAVYCPTPSGSMVTSETQLFNKPYWLRRAQGHNNGICWANQLFVTVVDTTRSTNMTLCVSTETSATYDATKFKEYLRHGEEYDLQFIFQLCKVTLTPEIMAYLHTMNSTLLEDWNFGLTLPPSTSLEDTYRFLTSSAITCQKDAPPTEKQDPYAKLNFWDVDLKDRFSLDLSQFPLGRKFLMQLGVGTRSSISVRKRSATTTSRTAAAKRKRTKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: Y8002_DICDI
Sequence: MVNNDAKIGRREFYDRVESVRPKSPPRERPTYTYSNSRTVDGYSNRGPRADF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0288577.
Protein: EFG_ACIF2
Sequence: MARTTPIERYRNIGIMAHIDAGKTTTTERILFYTGVSHKIGEVHEGTAVMDWMAQEQERGITITSAATTCFWKGMDGQRAEHRINIIDTPGHVDFTIEVERSLRVLDGAMAVFCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRQGANFKRVVDQIATKLRGNPVPVQLPIGEEDHFSGVIDLMKMKSINWDDALQGTRFTEEDIPPALQADAEAARHFMVEAIADADEDVMMKYLEGEEISIAELQAALRKATISGAVVPVLCGSAFKNKGVQAALDAVLDYLPSPVDIKPVEGTNPDNGEEIVRFADDSEPFSALAFKIATDPFVGQLTFFRVYSGVLTAGSTVLNPGRNQKERIGRVLQMHANERHEIKEVLAGDIAAAVGLKTAYTGDTLCDLNKPIALEQMEFPEPVIHVAVEPKTKADQEKMGIALGKLAQEDPSFRVRTDQESGQTIISGMGELHLEIIVDRMKREFGVEATVGAPQVAYRETIRKTVESEGKFVRQSGGRGQYGHVWLRLEPLEPGSGFVFENGVVGGTVPKEFINPTEKGVEEALENGIIAGFPVVDVKVTIFDGSYHDVDSSEAAFKIAGSMGFKAGAAKANPVLLEPIFAVEVVTPEEYMGDIIGDINSRRGMMQGMEDEAGAKLIRCEVPLAEMFGYATTVRSLSQGRATYTMQFEKYMEVPGHVAEAIVKKSQR
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_CUPMC
Sequence: MRGKFITFEGIDGAGKSTHIEWVAERLRARANVVTTREPGGTPLGEDLRQLLLHRKMHLETEALLMFAARREHIAEVIEPALARGDWVISDRFTDATFAYQGGGRGLALDRLATLEQWVQSGLQPDLTLLFDVPLETASARLAGAREPDKFEAESRAFFERTRTEYLRRAAEAPQRFRVIDATRSIDEIRVALEEIIATL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: POC1A_XENTR
Sequence: MAGQPEDPSLERHFKGHRDTVTTVDFNPNTKQLASGSMDSCLMIWNMKPQMRAYRFVGHKDAILSVDFSPSGHLIASASRDKTVRLWVPSVKGESTVFKAHTGTVRSVSFSGDGQSLVTASDDKTIKVWTVHRQKFLFSLNQHINWVRCAKFSPDGRLIVSASDDKTIKLWDKTSRECIHSFCEHGGFVNFVDFHPSGTCIAAAATDNTVKVWDIRMNKLIQHYQVHSGVVNSLSFHPSGNYLITASNDSTLKVLDLLEGRLLYTLHGHQGPVTSVKFSREGEFFASGGSDEQVMVWKTNFDSASYADLLKYRQHDQFLNGGDYTSGVPAADRHRPERNAQTDQADDLEPRHIQMSAKDRSSPLSYTSRSIDQHHPQAEDGNLRTVASTLEHIVGQLDILTRTVGILEQRLSLTEDKLKECIDNQQATVSLSHSATKTPSF
What is the function of this protein?
May play an important role in centriole assembly and/or stability and ciliogenesis.
What are the official names of this protein?
POC1 centriolar protein homolog A, Pat-interacting protein 2, Pix2, xPix2, WD repeat-containing protein 51A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat POC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with mitochondria in cortical germ plasm islands. The mitochondrial localization may be microtubule-dependent (By similarity).