PharMolix/UniProtQA huggingface dataset:
Protein: TRNP1_MOUSE
Sequence: MPGCRISACGPGAQEGTAEPGSPPPPPREPLPSLQPPSPSPTSTPTPTKSPPLPEAAETPVEGQELQRWRQGASGGSGGAGPAGIAGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGARRGRRGRPPALLASALGLGSCVPWGAGRLRRGQGPEPDSPFRRSPPRGPASPQR
What is the function of this protein?
DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex.  Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification.  May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points.
What are the official names of this protein?
TMF-regulated nuclear protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LENG9_MOUSE
Sequence: MEASADSSEAPAVCRFFLEGRCRFGARCRQPHPGAPAPSPVVTQPEAGSKKPALRTAADVIRRIRWDPRLDPADFSVGYTDRFLGVQEEPFCAFCWDEPLAALGPGVLAVPQHRIRYFRFRGRLVWDRASRTDLIFGSGSVAGRGPTILDALDGGDEHWTEVTAEIPDTEKTGVGLEGLDTQDALAEAGGNPTGTGLDSGLETHEEGGAIKETRTGLDSSLETPEVDGPTKETGLNGTTELEMPDPSMNFSGVKISSVEEPRATLLPQWQAQGMETKGLSAEEMGNVWDPGVWPDDRRAPRQPRPTHFVALMVTESGLRAEVVKAQEHLVRIAPSCAEFLVPAQALHLTVVLLRLTGPGEEAAAARALRRAILKPGLQAPSQLQFRDLVLLGHHVLCATPSPTLTGMAQTLNQRLEAEGLRVVLLPELQPHLTLAKVPHGTQVCLPKPEYTLNQELGRQPLSKLWLCRMGRAGHSYLPLVEISLK
What are the official names of this protein?
Leukocyte receptor cluster member 9.
Protein: ATPA_STAAW
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y2287_THEVB
Sequence: MADISYWTLLVPPLAGGVIGYFTNDLAITMLFRPYKPIYIGGKQVPFTPGLIPRNQERLARRIADAILGSLLTPEELQNLARRLLQVQRVKAVIHWLLQTSLSQIQAQSEQRSAQVLANILRDFFGSALPRLMKVWSRREDFLEPQLNQLFDQVLVELQLSDEQAEKLADWLLSVMLPPDRLRLAIIDFLTDRTINVLDQELRQNTSGTYWVVANLVGVRNTLIRLREYCLNEREACNRRLGDLITALALRQRLVEALQNLTLQSLPLGTVRELRQLFRQTVRSYIQEQGASVIETVSQTVEWETISLSILRRLRDSASLGASLEVVSDELALVLDRYLERDMELIVERAIPILDLDRVIVDRVKATSPENLELAIQGIVRSELQAIVRLGGILGFLIGVVQAGVLYWQSLQVP
What are the official names of this protein?
UPF0754 membrane protein tlr2287.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VE2_HPV54
Sequence: METLATRLDVCQERLLDLYEKDSNKLEDQIEHWKCIRLECALQYKAREMGYKVLQHQALPALAVSKGKGHKAIELQLALETLQKTVYSTEPWTLQDTCLERWNAPPTGCLKRRGQTVDVIFDGHQDNTMQYVMWGDIYYQNCDGEGWTKVCSNIDAMGIYYMDAEHKVYYVDFKKEASKYGEYGQWEVRMGSSIIFSPASVSSTEEALSISSTGTAEHTRPANSTPRTDNSTKAIPCTPPPRKRARVYSTDQQPHSTSDPVGCDNDRHISDDNNKNQGRHTSSGDTTPIVHFKGEPNTLKCFRQRIQKYKHLFEQASSTWHWACVPGTTKNRGIVTLTYSSVEQRQQFLVTVRIPPSISMSLGVMSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FENR_COLP3
Sequence: MKTLTTDVAIIGAGPVGLFQIFELGLQGLSTVVIDSLPEIGGQCSELYPDKPIYDIPALPNAKASEVIDNLWQQAAIFDPTFLLAERVEHIEKVSEHSFIVTTHKQTQIHCRAVVIAAGNGAFSPVKLKLPLIDKFEDTQLFYRISNIEHFRDKNVVVLGGGDSALDWSLTLQKTAKSVLLIHRSSNFKAAKSSVNKMYELCEQLKMQFLCGQVSSFQEKENKLTGLTITSKDGVNRRVELDELVVLFGMSPKLGPIDNWQLEMHQHQIKVDTQSFQTSVTGIYAVGDINYYPGKRKLILSGFHEAALAAFSIAETVLEKDRIPTLYTTTSPVVHQRLGVEHSLEAMLS
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: Y1709_XYLFM
Sequence: MLLHIPTILSRTQATSMQERLAAANWTDGRETVGPQGAQVKHNLQLPETSPLRQELGHEILDALARSPLYFAATLPLRTLPPRFNRYQENHQYGFHVDGAVMSLPVAPDHTPASLRSDISCTLFLNDPDEYEGGELIIADTYGEHEIKLPAGDLIIYPSTSLHRVAPVTRGMRIASFFWVQSLVRQATHRHQLLELDTAIQSLTASNTDHNTILRLTNIYHNLLREWSET
What are the official names of this protein?
PKHD-type hydroxylase Xfasm12_1709.
Protein: RPOA_EMIHU
Sequence: MFQVQCLESAQKAATENVAKFCIEPLSKGQGITIGNALRRTLLSNIPGTAIVGTRISGVDHEFSVIPGVKEDALEILLNLKQLVFKGNLNEPIITRLNIQGPCIVTAGDIDIPTDLELIDPQQYIATITDFSHLEMEFILEQGESYVLSEKTASNNPRGFLAVDAVFTPIKKVNFFVETSSSKERLEKERLIIEIETNGSILPLEALNLAAERLSSLFKLVNSADLTAEFPTEVENIVQVSQTDVTGVLIEELELSVRAYNCLKRAQIHTLGELLKYSKENLLEFKNFGQKSANEVCENLHERFNLTLN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAA_SHEB2
Sequence: MNKELQPKVIFLMGPTASGKTALALELAEKHNCEIISVDSALIYRGMDIGSAKPSADELARGPHRLIDIRDPRESYSAADFRADAIAEIELIVSMGKTPVLVGGTMMYFKALLEGLSPLPSADEAIRAEIQAEADEKGWEALHDQLREIDPVSAERIHPNDPQRLSRALEVYRISGKSMTELTQTKSAPLPYEVVQFAIAPRERKVLHDLIAQRFAIMLKQGFLEEVTELKARGDLHLDLPSMRCVGYRQCWQYLDGEFDYDTMVEKAVAATRQLAKRQLTWLRSWPELNWLESGAEGNLVTLMRQCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: 2ABA_CANTR
Sequence: MNLDFSQCFGDKGDIENITEADIISTVEFDHTGDFLATGDKGGRVVLFERNQSKKKQSCEYKFFTEFQSHDAEFDYLKSLEIEEKINKIKWLKSANDSLCLLSTNDKTIKLWKIQERQIKLVSENNLNGLNHLPSSNIGIESLKLPQLQLHDKLISAQPKKIYANAHAYHINSISVNSDQETYLSADDLRINLWNLGIADQSFNIVDIKPANMEELTEVITSAEFHPLQCNLFMYSSSKGTIKLSDMRSNSLCDSHAKIFEEYLDPSSHNFFTEITSSISDVKFSHDGRYIASRDYMTVKIWDLAMENKPIKTIDVHEHLRERLCDTYENDAIFDKFEVQFGGDNKSVMTGSYNNQFVIYPNAVNTGNDDKPKFKSAFKNSSKRSKKNGFSTRTTDDDDDDDDDDDDEEADDEFDEEVPATKNSPGSQLEDDDEQEEIILQADKSAFKSKKSGQHPMRRRMTSGVGSNLGREFDDVDFKKSILHLSWHPRENSVAIAATNNLYIFSTL
What is the function of this protein?
Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase.  The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates (By similarity).
What are the official names of this protein?
Protein phosphatase PP2A regulatory subunit B, Cell division control protein 55, PR55.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
Protein: PEPQ_LACDL
Sequence: MNLDKLQNWLQENGMDVAYVSSPTTINYFTGFITDPEERIFKLFAFKDAEPFLFCPALNYEEAKASAWDGDVVGYLDSEDPWSKIAEEIKKRTKDYQNWAVEKNGLTVAHYQALHAQFPDSDFSKDLSDFIAHIRLFKTESELVKLRKAGEEADFAFQIGFEALRNGVTERAVVSQIEYQLKLQKGVMQTSFDTIVQAGKNAANPHQGPSMNTVQPNELVLFDLGTMHEGYASDSSRTVAYGEPTDKMREIYEVNRTAQQAAIDAAKPGMTASELDGVARKIITDAGYGEYFIHRLGHGIGMEVHEFPSIANGNDVVLEEGMCFSIEPGIYIPGFAGVRIEDCGVLTKDGFKPFTHTSKELKVLPVKE
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U669_NEMVE
Sequence: MQGRYSAPLFLLLWLFFLHGTLCEQVLQTFTGEIGAGNYTYFTLNREGEITLILESTEGDADLYISQNVAKPDYENYDLQSSTCGQDVVTIPVEFKRPIGIGVLGHANSPLSKYTMTVVVDYGTGMAEDKNRWYSASEEGGEPQEESLIWMIFVGILKIIFEILL
What are the official names of this protein?
UPF0669 protein v1g209471.
What is the protein family that this protein belongs to?
Belongs to the UPF0669 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YA035_YEAST
Sequence: MRLNYSRCYYSSQRRRQSLPKRFPLI
What are the official names of this protein?
Uncharacterized protein YAR035C-A.
Protein: TGT_YERPB
Sequence: MKYELQKTDGRARRGRLVFERGVVETPAFMPVGTYGTVKGMTPEEVKETGAQILLGNTFHLWLRPGQEIMKLHGDLHDFMQWHGPILTDSGGFQVFSLGAMRKIKEEGVHFKNPINGDSVFLSPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAARSRQRFDELNNKNALFGIIQGGVYEDLRDVSVKGLVDIGFDGYAVGGLAVGEPKEDMHRILEHVCPQIPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKDDTATLDEHCDCYTCRHYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRQAIEEGKLEHFVEDFYGRIGKPVPPLNV
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: UBID_JANMA
Sequence: MKYSDLRDFISQLQQMGELKRINVPVSPYLEMTEICDRTLRAAGPALLFEQPTGQKIPVLGNLFGTPHRVALGMGATDVSELRKIGHVLAMLKEPEPPKGFKDIMGLGSLVKSIWDMAPKELRGAPCHDIVWEGNDVDLARLPIQHCWPGDIAPLITWGLVITKGPHKKRQNLGIYRQQVIGRNKVIMRWLAQRGGALDFREHSIVNRGQPYPIAVALGADPATILGAVTPVPDSLSEYQFAGLLRGSRTELVKALGSELRVPASAEIVLEGHIYPDESHPSGYEHALEGPYGDHTGYYNEQDSFPVFTIDRITMRRDPIYHSTYTGKPPDEPAVLGVALNEVFIPLLQKQFSEILDFYLPPEGCSYRMAVVQMKKAYPGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVNIRDWKEVIWAITTRVDPIRDTTLVDNTPIDYLDFASPVSGLGSKMGIDATNKWPGETDREWGRTITMTDEVKKRVDQIWQELGI
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YBEY_SULNB
Sequence: MHTIIELDNQTTLNVDIEALEKIAQSLTNREIELIITDNENIQELNREYRDRDNPTDVLSFPLETPFTEQSVFDIPLGTIVISADFVRERAKTYGHTEQDELKLLFIHGLLHLLGYDHETDEGEMRQKEREIIEEFGLPSSLIIRND
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHEB9
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAAAEAGALTTAAIKWFIKQYKIDMSEAAQSEPEAYKSFNAFFTRALKPGIRPLDMDADIMVHPVDGAVSQLGPIKNGRIFQAKGHHYSSLTLLGDQAEDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARNVPGLFARNERVVAIFETELGPLAMVLVGATIVASIETVWAGTVTPPTGKQVFTWEYPTQGPDAITLDKGEEMGRFKLGSTVVMLFAKDAIATFAEGVEAEAVTRMGQAFANLKDVKHAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LAC1_CRYNB
Sequence: MRGLAKLFFLSCSFVSLVSSEKTDESPTAVSDNYMPKATATIDPSVFALSNDFEITDVPTTREYTFDIAKAFASPDGYEREVYVVNNMFPGPVIEANTGDTIIVHVNNHLDEGQSLHWHGLRQLGTAFMDGVPGITQCPIPPGGSFTYNFTVSHQSGTYWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVFITDWMHDNSEIIIAALATPEGYKGNIAPPQGDAILINGRGQTNCTATGSSSCFYPPPPEIQVPVNCRVRLRFISATAHPMYRISIDNHPMEVVEADGTAVYGPTVHEISVAPGERYSAIINTNEGKEGDAFWLRTSVALSCMFGAVSQEGLAVVRYTGNGMVSTEEPQTSAWSDLAGVTVPCTGLDQTYTLSPRDSLSAPREPLQSHFFNSERGAFVNVLGNTFQGYGFNNISYQNQIFNPLLSIVQRGGSCENTLVSSRTFPDFGPGNIIINNLDTVIDHPYHLHGNEFQVIGRGTGALSIDNLTNIDFTLDNPVRKDTLWIQGGSWAVLRITADNPGVWALHCHIGWHLTEGKLAVIVVQPSAIGHMESPESWTNLCANTDPNAFGPAKRSSSPSIQSSKTSSFQYLREVKGKVVKRRGAREA
What is the function of this protein?
Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (PubMed:1100669, PubMed:6807845, PubMed:6804444, PubMed:8760791).  Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (PubMed:8300520).  Plays an important role in virulence (PubMed:8760791).  Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (PubMed:14977977).
What are the official names of this protein?
Laccase-1, Diphenol oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: VAB2_VANPO
Sequence: MRNKLNFQNIEHSYAFKELSKLPSIVSSKQLRTNSIFEAVKPELKNVQNDIQMFYSVIEREINSEISQIDLVETELKKSLKNVNKSYAKIMKRRTILSSNGKNKNLAIVDDFNKEVDGLESLITGLKETVHDMIDDLVTADSQLKSNNKSVTKEEINSQHYPLLFEILQKDYNHIFKESNNLSVQDADRKSIELDIEDRTEVKSSDDKDSMNKNINIMPIEDNSITHLSFEGEPIYTKVSHENSNQVTDKGINQLDENTLNQEIKNDNLICQRSLPPKNLSNENVVNDNYADSNCLKEEKKNEVDTSKSKMGTINSTPSSTTMGNGFILPNLTKVVKPTISTTFETVVNREF
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit VAB2, BLOC-1 subunit VAB2.
What is the protein family that this protein belongs to?
Belongs to the VAB2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Vacuole. Cytoplasm.
Protein: ISPD_XANC5
Sequence: MTGSIWAIVPAAGRGTRFGGPLPKQYLPAGGQPLMAYTLAALAAHPALAGIMVAIAPGDADWPGWTAVQSTPVLTCLGGASRAASVLAGLLALPESVRADDFVLVHDAARPNLALADLDRLLEIGRGDPVGAILAAPVRDTLKRAGDDGGIDGTEPRERLWRALTPQLFRRHQLIRGLTEAAAAGVEVTDEAMAMERMGLRPLLVEGAEDNFKVTTPADLARFEFELVNRGLGARDPESAHPQSSVLASAFSGPGSRVSGPEEI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: FE45_BRADU
Sequence: MRVMVDQDLCGTSGQCVLTLPGTFRQREPDGVAEVCVATVPHALHAAVRLAASQCPVAAIRVIESDAGDGERASADPAPSPAEAERHAAKDQHNLG
What is the function of this protein?
Electron transport protein for the cytochrome systems.
What are the official names of this protein?
Uncharacterized P450-system 3Fe-4S ferredoxin blr2145.1.
Protein: Y533_FUSNN
Sequence: MNNKLYGIILCFLLALPAWKLGKFFPLVGGPVFGIIIGIVIAILLKNRAKFDSGINFASKKVLQYAVILLGFGLNLQTIISVGSSSLPIIVSTISTSLIIAYILAKLINIPTKIVILIGVGSSICGGSAIAATAPVINAHDDEIAQAISVIFLFNVIAALIFPTLGDILNFSNKGFALFAGTAVNDTSSVTATASAWDSIHNTGTQVLDSATIVKLTRTLAIIPITLFLAVYNSKRSSNVNNFSLKKIFPMFIVYFILASIITTVCNYFIEVGVITENISITINNVFSFFKHLSKFFIIMAMVAIGLNTNIKKLILSGAKPLTLGFCCWFAISLVSIGLQKILGIF
What are the official names of this protein?
UPF0324 membrane protein FN0533.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRG_HUMAN
Sequence: MKALIAALLLITLQYSCAVSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDRVENTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLRVIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASFRVDRIERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVINCEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMFFTHTFPK
What is the function of this protein?
Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions.  Binds heparin and heparin/glycosaminoglycans in a zinc-dependent manner.  Binds heparan sulfate on the surface of liver, lung, kidney and heart endothelial cells.  Binds to N-sulfated polysaccharide chains on the surface of liver endothelial cells.  Inhibits rosette formation.  Acts as an adapter protein and is implicated in regulating many processes such as immune complex and pathogen clearance, cell chemotaxis, cell adhesion, angiogenesis, coagulation and fibrinolysis.  Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway.  This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions.  Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes.  Tethers plasminogen to the cell surface.  Binds T-cells and alters the cell morphology.  Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2.  Acts as a regulator of the vascular endothelial growth factor (VEGF) signaling pathway; inhibits endothelial cell motility by reducing VEGF-induced complex formation between PXN/paxillin and ILK/integrin-linked protein kinase and by promoting inhibition of VEGF-induced tyrosine phosphorylation of focal adhesion kinases and alpha-actinins in endothelial cells.  Also plays a role in the regulation of tumor angiogenesis and tumor immune surveillance.  Normalizes tumor vessels and promotes antitumor immunity by polarizing tumor-associated macrophages, leading to decreased tumor growth and metastasis.
What are the official names of this protein?
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDZ_MYCTO
Sequence: MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDRSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPCFDRLARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNLPATATVDDVRAIYVAAWKAKVKGITVYRYGSREGQVLSSAAPKPLLAQADTEFSGGCAGRSCEF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Vitamin B12-dependent ribonucleoside-diphosphate reductase, B12-dependent RNR, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase class-2 family.
Protein: BTB7_MYCBO
Sequence: MAEDVRAEIVASVLEVVVNEGDQIDKGDVVVLLESMKMEIPVLAEAAGTVSKVAVSVGDVIQAGDLIAVIS
What are the official names of this protein?
Biotinylated protein TB7.3.
Protein: CYB_MICFE
Sequence: MTVIRKTHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLAIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMIETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTVKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALLPLLHTSKQRALTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFTIILILMPIAGMIENNILNLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPISB_DANRE
Sequence: MSGRKFFVGGNWKMNGDKKSIEELANTLNSAKLNPDTEVVCGAPTIYLDYARSKLDPNIDVAAQNCYKVAKGAFTGEISPAMIKDCGVKWVILGHSERRHVFGESDELIGQKVAHALENGLGVIACIGEKLDEREAGITEKVVFAQTKFIADNVKDWSKVVLAYEPVWAIGTGKTASPQQAQEVHDKLRQWLKTNVSEAVANSVRIIYGGSVTGGTCKELASQKDLDGFLVGGASLKPEFIDIINAKA
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase B, TIM-B, Methylglyoxal synthase B, Triose-phosphate isomerase B.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX72B_SCOMU
Sequence: MLVFYALLFVSVFSSTVMGATIDKPILREAIEEIDVNKRAKNPYCKEENCPPGKHCPKVPIACVYGPCCF
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Kappa-scoloptoxin(07)-Ssm2b, Kappa-SLPTX(07)-Ssm2b, Kappa-scoloptoxin-Ssm2b, Kappa-SLPTX-Ssm2b.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-07 family.
What are the subcellular locations of this protein?
Secreted.