PharMolix/UniProtQA huggingface dataset:
Protein: TRM5_DROME
Sequence: MFIVSRLKDLTIITNRLRHYFRNMDVKELQPPSSVRGMQELQREQFRKIVQVPRLRVPESQVQRVMPLVKKFLLKMEHLHPVRAVDQSREILLHPTPVKNWDSLPTEDLQRQKVNAENFSFADLELRYENWSANEILKSVLPTEEEGLTSYSRIGHIAHLNLRDHLLPYKQLIGQVLRDKLPNCRTVVNKASSIDNTYRNFQLELICGDPDYQVETKENGVPFEFDFSKVYWNPRLSTEHERIVKMLKSDDVLYDVFAGVGPFSIPAAKKRCHVLANDLNPESFRWLQHNAKRNKCLPNIKMSNKDGRQFIVEELREDLLKRLCTTDTTTYGIHITMNLPAMAVEFLDAFRGLYSADELAQLPTNVCYPTVHVYSFAKGENTKELVRQLVESNLGASLDENLLQGINFVRNVAPNKDMYRVSFKLSLNMLTTLKEVEVTRKRYAEEELEVATKVKCV
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: DER_HELAH
Sequence: MNTSPRTLKTIAILGQPNVGKSSLFNRLAKERIAITSDFVGTTRDINKRKITLNGHEVELLDTGGMAKDAFLSKEIKAFNLKAAQMSDLILYVVDGKSIPSDEDIKLFREIFKINPNCFLVINKIDNDKEKERSYAFSSFGMPKSFNISVSHNRGISALIDAILDALGLTKIIEQDLDIDILESLETPNNTEDGNNEEEIIQVGIIGRVNVGKSSLLNVLTQKERSIVSSVAGTTIDPIDETILVKNQKICFVDTAGIRHKGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWDIRYAPYEEIMATLKRKFRFLEYAPVITTSCLKTRHIEEIKHKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLVKVYYATQFATKPPQISLVMNRPKALHFSYKRYLINTLRKEFNFLGTPLIINAKDKKSVQQN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: COAE_DEHM1
Sequence: MKIVGITGGIGSGKTTVCRYLKELGVNIIDADEIGHRVLQNKGIRTRITDVFGNEVMNPDGSINRKILGELVFGYPERLEHLNKITHPLIEQAIASLLEEYRQKGIKAVAIEAPLLVEAGWLKLVNEVWLITAPKESIFKRLRNRMGLSREQVMARIQSQATDNERLKYASIVINNNCRFEDLKSCVQLLAKERLELA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y125_HAEIN
Sequence: MPTLEKTFELKQRGSTVRQEIIAGLTTFLAMVYSVIVVPNMLGAAGFPAESVFIATCLVAGLGSILIGLWANAPMAIGCAISLTAFTAFSLVIGQKVAIPVALGAVFLMGVVFTLISTTGIRAWILRNLPSNIAHGAGIGIGLFLLLIAANGVGLVVSNQAGLPVKLGDFTSFPVMMSLIGLALIIGLEKMKIKGGILWVIIAITIVGLIFDPNVKFGGEIFKMPTFGENSLFLQLDFMGALQPAILPVVFALVMTAVFDATGTIRAVAGQADLLDKDGQIINGGKALTSDSISSLFSGLFGTAPAAVYIESAAGTAAGGKTGITAIVVGVLFLLMLFFQPLAFLVPGYATAPALMYVGLLMLSNVSKLDFDDFVGAMSGLICAVFIVLTANIVTGIMLGFAALVIGRIVSGDIKRLNVGTVIIAIVLVAFYAGGWAI
What are the official names of this protein?
Putative permease HI_0125.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_CHLCV
Sequence: MDYYDVLGVSKTASPEEIKKSYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDPQKRESYDRYGKNGPFAGAGGFGGMGGMGNMEDALRTFMGAFGGEFGGGGSFFEGLFGGLGEAFGMRGDPAGARQGASKKVHITLTFEEAARGVEKELLVSGYKTCETCLGSGAASEQGIKCCDRCKGSGQIVQSRGFFSMASTCPECGGEGRVITDPCSNCRGQGRIKDKRNVHVQIPAGVDSGMRLKMEGYGDAGQNGAPSGDLYVFIDVEAHPVFERRGDDLILELPIGFVDAALGMKKEIPTLLKEGMCRLTVPEGIQSGTILKVKNQGFPNVHGRGRGDLLVRVSVETPQNLSEEQKELLRKFATTEKAENFPKKRGFLDKIKGFFSDFAV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADA_PSEPF
Sequence: MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNTKVDPAEVEDVIWGCVNQTLEQGWNIARMASLMTQIPHTSAGQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVSMMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGITREQQDAFGVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKTFDYDETIRPETTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAQDLGIQPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRAGLGINDIDFFELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGVATMCIGLGQGISTVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_CUPPJ
Sequence: MESSEVLQEIREVNLAYLLLAQRLVRENQVEAMFRLGVSKEIADILAKLTSAQLVKLAASNMVLCRFRFDDHALLSTLTHTAKNHDMQQMHAAILLARQPVESLN
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CAMJE
Sequence: MKKEIHPEYVECKVSCACGNTFTTKSNKAELRVDICSNCHPFFTGSEKIVDAAGRVEKFKKKYAMQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: G6PI_SALAR
Sequence: MKNINPTQTSAWQALQKHYDEMKDVTIAELFAKDSDRFAKFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDDKDVMPEVNAVLEKMKTFSEAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKTAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPAQLEHVVPFKVFEGNRPTNSILLREITPYSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTX2_PIG
Sequence: MSLVAEAFVSQIAAAEPWPENATLYQQLKGEQILLSDNAASLAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYFEDHSKGSSSVRLS
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-2, Mitochondrial outer membrane import complex protein 2.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion.
Protein: MSHB_MYCS2
Sequence: MSSHESPRLLFVHAHPDDETLTTGGTIAHYVARSAEVHVVTCTLGEEGEVIGERYAQLAVDHADQLGGYRIAELTAALQSLGLRGPRYLGGAGHWRDSGMAGTPSRGRQRWVDADLDEAVGALVAVIGEVRPHVVVTYDPNGGYGHPDHIQTHVVTTRAVAAAPEAVGWTVPKFYWTVTAISAMTAGLQALGDVPSEWIRVNAEDIPFGFGDDQIDAVVDVTAELPAKVGAMRAHATQITVAPDGRAFALSNNIALPVLGEEHYVLVSGEAGPRDSRGWETDLLAGLDLE
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: GALS_ECOLI
Sequence: MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELDYRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAEKERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDNLSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGAGTPDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIPIARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQNAAAITNSTNQAM
What is the function of this protein?
Repressor of the mgl operon.  Binds galactose and D-fucose as inducers.  GalS binds to an operator DNA sequence within its own coding sequence (corresponding to residues 15 to 20).
What are the official names of this protein?
HTH-type transcriptional regulator GalS, Mgl repressor and galactose ultrainduction factor.
Protein: FOLD_CHRSD
Sequence: MTAQLIDGKAIAANVREQVSRQVQARRQEGKRAPGLAVVLVGEDPASEVYVRNKHRACDKAGVHSVQHKLPADTTQADLEALIDSLNADCSIDGILVQLPLPDHLDARPILERIRPDKDVDGFHPYNLGRLAQRLPVLRPCTPKGIMTLLQESGIHARGLDAVIVGASNIVGRPMALELMLAGSTTTVCHRFTRDLESHVRRADLLVVAVGRPGLVKGEWVKEGAVVIDVGINRQDDGKLAGDVEFAPAAARASYITPVPGGVGPMTVASLLENTLFAAELHDGMHA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SKN7_YEAST
Sequence: MSFSTINSNVNKTTGDSNNNTTENSSTADLLGMDLLQSGPRLMNTMQPNNSSDMLHINNKTNNVQQPAGNTNISSANAGAKAPANEFVRKLFRILENNEYPDIVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFVRQLNKYDFHKVKRSPEERQRCKYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKALLHFNSEGTNPNNPSGSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVELQKLNSKYNTVIESLITFKTINENLLNNFNTLCSTLANNGIEVPIFGDNGNRNPTGNTNPATTTAIQSNNNTNNASPATSTVSLQLPNLPDQNSLTPNAQNNTVTLRKGFHVLLVEDDAVSIQLCSKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLDGATATSIVRSFDNETPIIAMTGNIMNQDLITYLQHGMNDILAKPFTRDDLHSILIRYLKDRIPLCEQQLPPRNSSPQTHSNTNTANSNPNTINEQSLAMLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQHQIFHAQQQQQHHNAIANARSDVAIPNLEHEINTVPHSSMGSTPQLPQSTLQENQLS
What is the function of this protein?
Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment.  Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1.  Also activated in response to oxidative stress, independent on the two-component regulatory system.  Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.
What are the official names of this protein?
Transcription factor SKN7, Peroxide sensitivity protein 9.
What is the protein family that this protein belongs to?
Belongs to the SKN7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_ACISJ
Sequence: MIKLFVGLGNPGPEYEATRHNAGFWWIDALARELKVTLVPERSYHGLVARASVAGHSVWLLQPQTFMNLSGKSVAALARFFKIPPEEILVAHDELDIPPGQAKLKRGGSHAGHNGLRDIHAQLGTSDYWRLRIGIGHPGVKAEVVNWVLKKPAPDQRTLIEDSILHSLKAYPALLAGDMDKATLLVHTTKPPRPKTARPAQAQAAPQAGAD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ECO55
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQSALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: ATPG_IDILO
Sequence: MASGKEIKTQISSIGNTQKITSAMEMVAASKMKKAQERMEASRPYADTIRKVIGHVARGNLEYRHPFMEERQVKRVGYIIVSTDRGLCGGLNGNEFKKVVKHANEWKEQDVEADFAAIGSKGTSFFKRFGKLKAQVSGMGDKPELKEITGSIQVMLDAFEEGKIDRLYVVFNKFVNTMTQEPTIHQLLPLPQAGSEEDVQTGSWDYLYEPNPESILDTLIRRFVEMQVYQGVVDNFASEQAARMIAMKAATDNAEDIIDQLQLRYNKARQAAITQEISEIVSGAEAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ABI3_MOUSE
Sequence: MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHMEKVARREIGTLATVVRLPSNQKVIPPESLPSLTPYHRKPLNFACLDDIGHGVKDLSTQLSRTGTLSRKSIKAPATPVSATLGRPPRIPEPVQLPAVPDGKLSAASSASSLASAGSAEGASGIPQSKGQVAPATPPPPPVAPVTPPPPPLSAEVFLPPPPLEVSQPPLEAELPLPPPPALEGDELGLLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
What is the function of this protein?
Inhibits ectopic tumor cell metastasis of SRD cells.  In vitro, reduces cell motility.
What are the official names of this protein?
ABI gene family member 3, New molecule including SH3, Nesh.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPY30_CAEEL
Sequence: MADQTASAEVATEKMDTAEAPAAAPAASAAAPAEAESNENTTVPSNVLSANGGQQTGNQSAPRNTSTVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNAENQNPAGQQ
What is the function of this protein?
Essential for dosage compensation (PubMed:7588066).  Required for the sex-specific association of the dosage compensation complex proteins dpy-27 and dpy-26 with the hermaphrodite X chromosomes (PubMed:7588066, PubMed:8939869).  Plays a role in developmental rate and body fat regulation downstream of the TOR complex 2 (PubMed:23884442).  Required for the robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development (PubMed:25124442).
What are the official names of this protein?
Dosage compensation protein dpy-30, Protein dumpy-30.
What is the protein family that this protein belongs to?
Belongs to the dpy-30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAA_STAEQ
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKRMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKATINAKSDELFFGLPSEQTVWMSHSDKVIEIPEGFEVIADSPSTNYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLRNFVRRVCNCTGEWTMENFIEIEIEKIRQQVGNRKVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFDMNIIRVNAQERFMSKLKGVSDPERKRKIIGNEFVYVFDDEAAKLTDVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREVIREEGLERDIWQYFTVLPGIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GP1_BPPH2
Sequence: MGKIFDQEKRLEGTWKNSKWGNQGIIAPVDGDLKMIDLELEKKMTKLEHENKLMKNALYELSRMENNDYATWVIKVLFGGAPHGAK
What is the function of this protein?
Protein that assembles into highly ordered structures and provides a specific site for viral DNA replication.  Probably anchors the viral DNA replisome to the host membrane.
What are the official names of this protein?
DNA replication protein 1, Gene product 1, gp1.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus DNA replication protein 1 family.
What are the subcellular locations of this protein?
Host membrane; Peripheral membrane protein.
Protein: 3L22_OPHHA
Sequence: TKCYVTPDATSQTCPDGQDICYTKTWCDGFCSSRGKRIDLGCAATCPKVKPGVDIKCCSTDNCNPFPTWKRKH
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 2, Neurotoxin B.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RHAB_LISIN
Sequence: MKHYVAVDIGASSGRLILGKLVNEKLQLEEIHRFKNGFTYRDGHERWEIDQLMQEIFIGLEKVKQLGISECVLGIDTWGVDYVLIGASGEKLADPISYRDKRTLNAVQNLTSEYPREYIYKKTGIQFMELNTLYQLYVEERNLLERAEKILLIPDYIGYVLTGVKVAETTNSSTTQMLNLREQLFDKDLLSHLNIDVEKFAPLTDAGTYLGKVKAEWLEEYDIPNCDVVTVATHDTASAVVGTPAEGENWAFLSSGTWSLIGMELIAPINNEAAFKENYTNEWGAYGTYRFLKNIMGLWIVQEIARMDDYKHSFAEMAEEASNYPYFKQIINVNDARFNNPENMVDEIKLYCQETGQTVPETIGELTNCVYGSLALYYALELEKMTEITGKKIEKLYIVGGGSNVAMLNQLTAKLAGIEVFAGPSEATAIGNLVVQMINQGEIESMRAGRKIIRNSFEIGEFSCGDVRFEEIKERFTKVLEFN
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: SSPA_STAA8
Sequence: MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPDAA
What is the function of this protein?
Preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate.  Along with other extracellular proteases it is involved in colonization and infection of human tissues.  Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB.  It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells.  May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM.  May be involved in the stability of secreted lipases.
What are the official names of this protein?
Glutamyl endopeptidase, Endoproteinase Glu-C, Staphylococcal serine proteinase, V8 protease, V8 proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: UGGG1_RAT
Sequence: MCSRGDANAAGAAAARRVTGLCYNMGLLIALALLCLFSLAEANSKAITTSLTTKWFSAPLLLEASEFLAEDSQEKFWSFVEASQNIGSSDQHDTDRSYYDAILEAAFRFLSPLQQNLLKFCLSLRSYSASIQAFQQIAVDEPPPEGCKSFLSVHGKQTCDLGTLESLLLTAPDRPKPLLFKGDHRYPSSNPESPVVIFYSEIGHEEFSNIHHQLISKSNEGKINYVFRHYISNPRKEPVHLSGYGVELAIKSTEYKAKDDTQVKGTEVNTTVIGENDPIDEVQGFLFGKLRELYPSLEGQLKEFRKHLVESTNEMAPLKVWQLQDLSFQTAARILAAPVELALVVMKDISQNFPTKARAITKTAVSAQLRAEVEENQKYFKGTIGLQPGDSALFINGLHIDLDTQDIFSLFDTLRNEARVMEGLHRLGIEGLSLHNILKLNIQPSETDYAVDIRSPAISWVNNLEVDSRYNSWPSSLQELLRPTFPGVIRQIRKNLHNMVFIVDPVHETTAELVSIAEMFLSNHIPLRIGFIFVVNDSEDVDGMQDAGVAVLRAYNYVGQEVDGYHAFQTLTQIYNKVRTGEKVKVEHVVSVLEKKYPYVEVNSILGIDSAYDQNRKEARGYYEQTGVGPLPVVLFNGMPFEKEQLDPDELETITMHKILETTTFFQRAVYLGELSHDQDVVEYIMNQPNVVPRINSRILTAKREYLDLTASNNFYVDDFARFSALDSRGKTAAIANSMNYLTKKGMSSKEIYDDSFIRPVTFWIVGDFDSPSGRQLLYDAIKHQKTSNNVRISMINNPSREISDSSTPVSRAIWAALQTQTSNSAKNFITKMVKEETAEALAAGVDIGEFSVGGMDVSLFKEVFESSRMDFILSHALYCRDVLKLKKGQRVVISNGRIIGPLEDSELFNQDDFHLLENIILKTSGQKIKSHIQQLRVEEDVASDLVMKVDALLSAQPKGEARIEYQFFEDKHSAIKLKPKEGETYYDVVAVVDPVTREAQRLAPLLLVLAQLINMSLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTADNSFAKGPIAKFLDMPQSPLFTLNLNTPESWMVESVRTPYDLDNIYLEEVDSIVAAEYELEYLLLEGHCYDITTGQPPRGLQFTLGTSANPTTVDTIVMANLGYFQLKANPGAWILRLRKGRSDDIYRIYSHDGTDSPPDANDVVVILNNFKSKIIKVKVQKKADMANEDLLSDGTNENESGFWDSFKWGFSGQKTEEVKQDKDDIINIFSVASGHLYERFLRIMMLSVLKNTKTPVKFWFLKNYLSPTFKEFIPYMAKKYNFQYELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLVVDKFLFVDADQIVRTDLKELRDFNLDGAPYGYTPFCDSRREMDGYRFWKSGYWASHLAGRKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTIDLCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQLQTLFQEEKELGTLHEEETQEGSQKHEEL
What is the function of this protein?
Recognizes glycoproteins with minor folding defects.  Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum.  Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
What are the official names of this protein?
UDP-glucose:glycoprotein glucosyltransferase 1, UGT1, rUGT1, UDP--Glc:glycoprotein glucosyltransferase, UDP-glucose ceramide glucosyltransferase-like 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Endoplasmic reticulum- Golgi intermediate compartment.
Protein: RL15_GLOVI
Sequence: MKSLRLEDAVPQSGSRHRKLRVGRGHSAGQGKTSGRGMRGQKCRSGGGVRPGFEGGQIPLYMRLPKLKGFELVNPSSYTIVNLKQLRDLPADSEVNIETLLDAGILTATSGPLRVLGDGEAHVALQITAAYFTASAREKIEAAGGTCTVEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y1639_YERPN
Sequence: MSELCPCGSILNYHECCGPYILGTQVAAKPAILMRSRYCAYVEKNVDYLIATWHPDCHAQEWRESIIQGFTKTVWHGLTVIAETPGRHPDEAFVEFIARFTDADNAQITAMHERSRFLRIKEHWYYIDGIRPSLGRNDTCLCGSGKKHKKCCGR
What are the official names of this protein?
UPF0225 protein YPN_1639.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.