PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_XYLFA
Sequence: MLVAIEGIDGAGKTTLARSLALKLRGVGLETVVSKEPTNGPWGMLLRQSAATGRFSPEEEVDVLLRDRRQHVEDLIVPMIGRGAVVILDRYFPSMVAYQGAAGLPVDALLEANAFAPRPDVLLLLDVPPAIGLQRIWERGSTPNHFETTENLSRCRDIFLALELPSKRVIDATANAETVLSAALALVMEVLRVRLGALGAVVLRRLAG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RS4_SHIFL
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVPGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PRS4_HUMAN
Sequence: MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 4, P26s4, 26S proteasome AAA-ATPase subunit RPT2, Proteasome 26S subunit ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Lipid-anchor.
Protein: RL13_BRUSU
Sequence: MATFSQKPAEVVKKWVLIDAEGLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVYAGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PSAB_CITSI
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVQDPLHVRPIAHAIWDPHFGQPAVEAFSRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGEYVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGSGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTDGPAFNAGRSIWLPGWLSAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWNHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: RNH_GRABC
Sequence: MDTMQGESNIVEIWTDGGCKPNPGPGGWAAILLYRGTEKELSGFDPETTNNRMELTAAAAALEALTRPCKVVLNTDSEYVRNGITRWKDGWVRRNWRNASGDPVANMDLWRRLLDAAARHEIDWRWVRGHAGNPMNERADQLATKARMEG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_BRUA4
Sequence: MLEFYGQKFESRLLLGTAQYPSPAILADAVRASQSDIVTVSLRRESGEARAGQDFWALIRELGVAVLPNTAGCHTPREAVTTAKMAREIFGTNWIKLEVIGDTDTLQPDPFGLVEAARALCDDGFEVFPYMNDDLVVAERLIEAGCKVLMPWGAPIGSGRGLNNPYALKTMRAHFPDIPLVVDAGIGVPSHAAAAMELGYDAVLINTAVAKAGDPVAMARGFALAVEAGRLAFEADAIEARDMAAPSTPLLGKAFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPEL_STRP4
Sequence: MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQIRTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLLFASQHQGRMHACGHDFHMTIALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLKVGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVVASYFVTQVQSVVSRNVNPIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFDMEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDGVMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: COX7C_THUOB
Sequence: SHYAEGPGKN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase polypeptide 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CYB6_AMBTC
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFHCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEVNFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPRDQIGYWAVKIVTGVPEAIPIIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RRF_ACIBT
Sequence: MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVEDSRTLIVQPFERTMVAAIDKAIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEAENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQKITDKYVAEVDKRLAAKEAELMKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_ECOLC
Sequence: MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RR19_SECCE
Sequence: MTRKKTNPFVAHHLLAKIEKVNMKEEKETIVTWSRASSILPTMVGHTIAIHNGKEHIPIYITNPMVGRKLGEFVPTRHFTSYENARKDTKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ZDS1_YEAST
Sequence: MSNRDNESMLRTTSSDKAIASQRDKRKSEVLIAAQSLDNEIRSVKNLKRLSIGSMDLLIDPELDIKFGGESSGRRSWSGTTSSSASMPSDTTTVNNTRYSDPTPLENLHGRGNSGIESSNKTKQGNYLGIKKGVHSPSRKLNANVLKKNLLWVPANQHPNVKPDNFLELVQDTLQNIQLSDNGEDNDGNSNENNDIEDNGEDKESQSYENKENNTINLNRGLSRHGNASLIRRPSTLRRSYTEFDDNEDDDNKGDSASETVNKVEERISKIKERPVSLRDITEELTKISNSAGLTDNDAITLARTLSMAGSYSDKKDQPQPEGHYDEGDIGFSTSQANTLDDGEFASNMPINNTMTWPERSSLRRSRFNTYRIRSQEQEKEVEQSVDEMKNDDEERLKLTKNTIKVEIDPHKSPFRQQDEDSENMSSPGSIGDFQDIYNHYRQSSGEWEQEMGIEKEAEEVPVKVRNDTVEQDLELREGTTDMVKPSATDDNKETKRHRRRNGWTWLNNKMSREDDNEENQGDDENEENVDSQRMELDNSKKHYISLFNGGEKTEVSNKEEMNNSSTSTATSQTRQKIEKTFANLFRRKPHHKHDASSSPSSSPSSSPSIPNNDAVHVRVRKSKKLGNKSGREPVEPIVLRNRPRPHRHHHSRHGSQKISVKTLKDSQPQQQIPLQPQLEGAIEIEKKEESDSESLPQLQPAVSVSSTKSNSRDREEEEAKKKNKKRSNTTEISNQQHSKHVQKENTDEQKAQLQAPAQEQVQTSVPVQASAPVQNSAPVQTSAPVEASAQTQAPAAPPLKHTSILPPRKLTFADVKKPDKPNSPVQFTDSAFGFPLPLLTVSTVIMFDHRLPINVERAIYRLSHLKLSNSKRGLREQVLLSNFMYAYLNLVNHTLYMEQVAHDKEQQQQQQQQP
What is the function of this protein?
When associated with DBP5, GFD1 and nucleoporins at the cytosolic fibrils of the nuclear pore complex, is required for mRNA export form the nucleus.
What are the official names of this protein?
Protein ZDS1, Protein NRC1, RT2GS1.
What is the protein family that this protein belongs to?
To yeast ZDS2/MCS1.
Protein: PGSA_MYCGE
Sequence: MDWKTSEMLFPFPVYMAPLTSKFAAYKKKIANWLTVYRIFIALPTIIFIALDNQLGVLANFSVGAISISLQISLLIGGFLFLTAVISDYLDGYLARKWLAVSNFGKLWDPIADKVIINGVLIALAINGYFHFSLLIVFIVRDLVLDGMRIYAYEKKVVIAANWLGKWKTIMQMVGIVFSCFVWSFKQSEIASLNSGLFFWLLTQLPYYLAAVFSIWSFIVYNIQIYQQLKAYNSKL
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADR_ECO55
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN11_RAT
Sequence: MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDSKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDECALKEYGVMRVRNVRESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR
What is the function of this protein?
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus (By similarity).  Positively regulates MAPK signal transduction pathway (By similarity).  Dephosphorylates GAB1, ARHGAP35 and EGFR (By similarity).  Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity (By similarity).  Dephosphorylates CDC73 (By similarity).  Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification (By similarity).  Dephosphorylates tyrosine-phosphorylated NEDD9/CAS-L (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase SYP, SH-PTP2, SHP-2, Shp2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCN_MOUSE
Sequence: MPSCTASTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRAFPEHSPEPSNWATEMLLPEADLWGNPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVNEKLQHGHGPPGVSSACSAPGVGASSPGGRALGGSSSASHTGATLPTDLSHPAAECVDPAVVFPFPVNKRESASVPAAPTSAPATSAAVTSVSVPATAPVAAPARAGGRPASSGEAKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNNKAVTTFTITVRPKTSALGLGRAQPGELILKRCVPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVVPAKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHALQANEHQLLLEKEKLQARQQQLLKKIEHARTC
What is the function of this protein?
Positively regulates the transcription of MYCNOS in neuroblastoma cells.
What are the official names of this protein?
N-myc proto-oncogene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_MESFL
Sequence: MAYKIKKVNRGVERRDYRKVSGNLELPNLIEIQTKTFEWFKTKGIDEVLNEFFAMSSNDASASLFLEGWEIKEAKISPSKAKEQSKIYDAPIYVDLQLMFTKTEDISKEFEEIVEKDVKKVLSNWIAEKTDSKNVSLVKNTDNIYFFDVKLKGTEKNDLFQITILEEKEDIIVAEVSVRKWGQVFFGDFPLMTDAGTFVINGSQKVIVSQLVRSPGSYFKTEINNKTGESLYNGDIIPSRGTWLEFETDTKKTAETTNSLFVKIDKSRKTTATSFLKILGLDRDTILNIYDKDKVIVETLKNDNDTGDTYADWAQHVQEIYKKIRQGETATSDGASKYINGLLFDRRKYDLTKAGRFKLQQKLAVKNRLMGRILAEDIVDASGKILVAKNTEISKANIKEVSDALSQDGVMVSSIEYREDIPGSRQIQKVKVYQDNNSKDETFTIVGITPNSKEEHITVVDIVATVSYLLGLEYNIGEYDDIDNLANRRVRTVGELLQNQFRMGLTRIDKNVKEKLSTSDLYKVKVSTIINAKPLTAVIGEFFNLSQLSQFMDQINPLAELTNKRRLTALGPGGLSRDRASLEVRDVHPSHYGRICPIETPEGPNIGLINNLSTYAIVDELGFIRTPYLKVIDGVIQNEHEYLSADEEKEYIISQSNVTKDENGKILDETVVSHYKGDDYIAKVSEVQFIDVSPKQIVSVATSAIPFLENDDANRALMGANMQRQAVPTIVPESPFVGTGIEFEAARDSGVCIVATENGIVKYVDAKQITVESKAGIKTYTLANFERSNNGSSIVQKPIVKVGDSIEAGQIIADGPSVDNGELALGQNVVVAFTTYNGYNFEDAIVMSERVIMEDKFTSVHIDEYVLEVRNTKQGAEEITSEIPNISDNAKKYLDNEGIVAIGTEVKTGDILVGKVTPKGQTQLSPEDKLLHAIFGEKSRSVKDNSLKVPNGGEGIVQSVKRFKAKSAANPDGIDLPADVLEVIKVYIVQKRKIQEGDKMSGRHGNKGIISKVLPVEDMPHLEDGTPVDILLNPQGIPSRMNIGQILEIHLGMAAKKLGVKIATPVFEGVNSNDLDEIMAEAGMENYGKVKLIDGQTGEAIDKPISVGVMYMLKLSHMVDDKLHARSVGPYSLITQQPLGGKAQNGGQRFGEMEVWALEAYGAAHTLREILTIKSDDLKGRTKTYEAIVRSKNIPTPGTPESFNVLSKEIMGLGFDIYLLDNKGNKSQINAYDDDNDLINDESMKHASIDKLTFEDSISLVEIEDLDSFEEVDESEINLSFEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: LPXB_PSEA8
Sequence: MADGLRVALVAGEASGDILGSGLMQALRARHPDIEFIGVGGPRMEAEGLSSYFPMERLSVMGLVEVLGRLPELLRRRKRLIRTLIEARPDVMIGIDAPDFTLGVEHKLRQAGLRTVHYVSPSVWAWRQKRVLKIREACDLMLALFPFEARFYEEHGVPVRFVGHPLANTIPLQADRAAARARLGLPADGQVLALMPGSRGGEVGKLGALFLDTAQRLLVERPGLRFVLPCASAARREQIEQMLQGREPLPLTLLDGASHEALAACDAVLIASGTATLEALLYKRPMVVAYRVAGLTYRILKRLVKSPYISLPNLLAGRLLVPELIQDAATPQALAATLSPLLDDGSQQVEFFDAIHRALRQDASAQAAEAVLQLVERR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: IF1_WOLSU
Sequence: MAKDDVIEVDGKVIEALPNATFRVELDNKHVILCHIAGRMRMHYIKILPGDRVKIELTPYSLDKGRITFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_DESVM
Sequence: MKIIRARTAGFCMGVSLALRKLDREVTENNAPIATLGPIIHNPQVMAHYEERGVRCLRDTAQVVPGQRVVIRAHGIPVAEETALKATGASVVDATCPKVKRAQLGIAEERGRGGTLLLFGEADHPEVRGLLSYAGEGAMVFGSLDELKGLPLRDDVAYFLAAQTTQDRAGFEDVVSWLRQRLGHDIPVLQTICDATRKRQQEAVDIARRVQAMVVVGGFDSGNTRRLADVARAQGVFTVHVETVDQLPVDELRKKSVIGLTAGASTPKSLIDAVQRFLESL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RBL2_CERS1
Sequence: MDQSNRYARLDLKEADLIAGGRHVLCAYVMKPKAGYGYLETAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEIDPEKEIMKIAYPVELFDRNIIDGRAMLCSFLTLTIGNNQGMGDVEYAKMHDFYVPPCYLRLFDGPSMNIADMWRVLGRDVRNGGMVVGTIIKPKLGLRPKPFADACHEFWLGGDFIKNDEPQGNQTFAPLKETIRLVADAMKRAQDETGEAKLFSANITADDHYEMVARGEYILETFGENADHVAFLVDGYVTGPAAITTARRQFPRQFLHYHRAGHGAVTSPQSMRGYTAFVLSKMARLQGASGIHTGTMGYGKMEGEAADKIMAYMLTDEAAEGPFYRQDWLGLKATTPIISGGMNALRLPGFFDNLGHSNVIQTSGGGAFGHLDGGTAGAKSLRQSHEAWMAGVDLVTYAREHRELARAFESFPADADKFYPGWRDRLQRAA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: SYA_PEDPA
Sequence: MERKSSSEIRRMYLDFFKSKGHIIEPSASLVPQDDPTLLWINSGVATMKKYFDGSVVPEVPRLTSSQKSIRTNDIENVGHTARHHTLFEMLGNFSVGDYFKEEAIHWAWELLTSKEWYGMDPEKLYVTVYPKDEEAKKIWLETPIDPSHIVKVEDNFWDIGEGPSGPDSEIFYDRGEAFNNLEDDDPENYPGGENERWLEIWNIVFSQFNHKPDGTYEPLPHKNIDTGMGLERVVSVFQDAPTNFETDLFLPIIHEVEKLSGKKYGENKESDISFKVIADHARAITFAIGDGAIPSNEGRGYVIRRLLRRAVMHGKQLGVNETFLYKMVPVVGEIMKDYYPEVLADQDYIAKVIKSEEDRFSETLTDGLELLNTIIDETKTKGSDTISGFDAFRLFDTYGFPLELAKEYASDKGLKVDEAGFEDEMQKQKERARSARSTEKSMGVQSDLLTDLKTESKYVGYDTLRVDNAILENVIQDGKLTDIVEPGEARVLFNITPFYAEMGGQVADQGEIRDANGEIVAEVIDVQHAPNGQNLHTIKALKKMHSGAAYTLEVNRAFHLKVEKNHTATHLLDQALRDILGDHTQQAGSLVEPGYLRFDFTHFGQVTNEDLDRVEKIINEKIYDEIPVTTVETDLETGKKMGAIALFNDKYGKKVRVVGIGDYSKEFCGGTHVKNTNEIGLFKIVSESGVGAGVRRIEAVTSQAALEFLNTEENLLKQTAGLLKSAQLKDVPTKTEQLQSNVKALTQKISQLEAKIAKSQAANIGDEMVEINGVRLIAADVQVSGMDQLRQMADDWKNKDQSDVLVLAAKIGEKANLIAAVKDDFVKKGLKAGDLIKAIAPKVNGGGGGRPNMAQAGGSNPDNIKAALQAAREWLESQNG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1310_DESAP
Sequence: MPVTSELILAALLLVGVLAKSHLIAAAACILLFIKLARFDLAFNFLEQKGLELGLLILLLTIMVPLANGKISERDIIYNLTSIPGLLAILGGALATHLNSQGLQMMQADPAIIFGLIIGSIFGILFLGGMPVGPLMAAGIAALFMEFFKYTK
What are the official names of this protein?
UPF0756 membrane protein Daud_1310.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNDA_MACFA
Sequence: MANEYKKILLLKGLELMDEYHFIIIKSLLAYDLGLTTKMQEEYNRIKISDLMEKKFQGVACVDKLIELAKDMPPLKNLVNNLRKERSKVARKMKAQGVVLMKKINQEEVGLVAPAPTARNTLTSEVGERIPVAQKRKTLSKGKTEAKRIKVPQEQSEPPHPSGASTSAATDHPPLPHTSSSTPSNTSFAQNQQTQAQCQVDTRRNVPQKDPVTVMVLKATAPFKYESPEHGKSTMFHATVASKTQYFHVKVFDISLKEKFIRKKVITISDYSECKGVMEIKEASSVSDFDQNFEVPNRIIEIANKTPKISQLYKQASGTMVYGLFMVQKKSIHKKNTIYEIKDNTGSMDVVGNGKWHNIKCEKGDKLRLFCFQLRTVNRKLKLVCGSHSFIKVIKAKKNKEGSMNVN
What is the function of this protein?
May act as a transcriptional activator/repressor in the myeloid lineage.  Plays a role in the granulocyte/monocyte cell-specific response to interferon.  Stimulates the DNA binding of the transcriptional repressor protein YY1 (By similarity).
What are the official names of this protein?
Myeloid cell nuclear differentiation antigen.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin (By similarity).