PharMolix/UniProtQA huggingface dataset:
Protein: YX35_YEASX
Sequence: GNATSERLPTDPVYPXV
What is the function of this protein?
Putative component of the large subunit of mitochondrial ribosome.
What are the official names of this protein?
54S ribosomal protein YmL35, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YPUM_RHOCA
Sequence: MILSRRMIGSLAMTWLPFADAASETLPLRQLLRLSLFQVSVGMAQVLLLGTLNRVMILELGVPALVVAAMISIPVLVAPFRAILGHRSDTYRSALGWKRVPYLWFGSLWQMGGLALMPFSLILLSGDQTMGPAWAGEAFAGVAFLMAGVGMHMTQTAGLALAADRATEETRPQVVALLYVMFLIGMGISAVIVGWLLRDFDQITLIRVVQGCGAMTLVLNVIALWKQEVMRPMTKAEREAPRQSFREAWGLLAAETGALRLLATVMVGTLAFSMQDVLLEPYGGQVLGLKVGQTTWLTAGWAFGALVGFIWSARRLSQGAVAHRVAARGLLVGIVAFTAVLFSPLFGSKVLFFASAMGIGLGSGMFGIATLTVAMMVVVRGASGIALGAWGAAQATAAGLAVFIGGATRDLVAHAAAAGYLGSLHSPALGYTVVYVTEIGLLFITLAVLGPLVRPGSLFPKKPEAGEARIGLAEFPT
What are the official names of this protein?
Uncharacterized protein in puhA-bchM intergenic region, ORF477, Protein F1696.
What is the protein family that this protein belongs to?
Belongs to the PucC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GNA2_ORYSJ
Sequence: MASTSPEPSTAAAVAETGCSVQIRRLEATDHEKGFVALLSQLSACPDLTASEFAACFADLAALGDDHVILVAEDPAAPESRILATGCLFVERKFLRGGGKVGHVEDVVVDAAARGRGLGLRVVRRLVEIAKEAGCYKVILDCTPELRAYYAKCGFVEKGVQMAIYF
What is the function of this protein?
Acetyltransferase involved in UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis.  UDP-GlcNAc is an essential metabolite that serves as an initial sugar donor of N-glycan synthesis and thus plays an important role in protein and lipid glycosylation (By similarity).
What are the official names of this protein?
Probable glucosamine 6-phosphate N-acetyltransferase 2, Glucose-6-phosphate acetyltransferase 2, Phosphoglucosamine acetylase 2, Phosphoglucosamine transacetylase 2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNA1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: TUSD_ECODH
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGVYNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQQGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SACD2
Sequence: MQVSLETTTGLERKLTVGIPASVVDQEVAKRLKEAAKTVRINGFRKGKVPMSVVQQRYGAGVRQEVLGDAINRSFYDAVRKESLRPAGQPAIEPKQLEPGKDIEFVATFEVYPEIEVSGLESIEVTRYNAEVTDADVDTMIETLQKSQADWAPVKRKSKKGDRVVIDFKGTKDGEAFEGGTAEGQTLVLGSNSMIPGFEKGIIGMKAGETETIKVTFPDDYQEESLRGAEAEFEVTVQKVEGQKLPKLDDEFFAKFGVTEGGEEKFRADVRENMEREKQKALKGKLKEQVMNGLVAANTVDIPKSLVSGEIDALRNQMGNQMMQQYGSQAEGIDFKSILPDDMFKEQAERRVALGLIVSEIVKNEKISVDKELVKSLIEDVASTYEHPEEVVNYYYGNEQLLGGVEAAALEEQVVSLVLSKAKVSDETISYEEAVKPAAKQAEE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: QUEC_STAA8
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: WDR12_IXOSC
Sequence: MGETAQIQAKFFTKDERYSVPDTPFSIAGSTTPEQLSSLINALLKESSASPDQDEQPAFDFLINGELLRLTLEEHLETKEIPQETIVHLEYLEKCPPPSPVDSLIHDDWVSAVHASEAGILSGCYDNTLHIWDTATGTRRLTIPGHLGPIKSVKWVAVAEPPCTFVSTSHDETAMLWQWDRRTNAVESVQVCRGHARSVDCVDVSWNGAKFVTGSFDHMLKVWSADPDSTDTDHGQDGSEEGSRKKQKTVDGKAKTRVPVLTLAGHHEAVTGVQWTDEGEVATCSMDHTLRIWDVELGGMKSQLAGSKAFLGISYSRLNRQIVSASSDRHVRLWDPRTKDGTIVKCSYTSHAGWVSAVHWAPNSDHQFISGSYDTLMKLWDARSPKAPLYDMSGHEDKVLAVDWSLGKYMISGGADNQLKIFEHK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: HIS8_HAHCH
Sequence: MSVKDRILQWVRPEVQALSAYHVADASGLIKLDAMENPFDFPAALKAELGVDLRDAAINRYPDPDAGAIRTALRELYSLPASADMLFGNGSDEIIQILAMAVAGPGRTILSVEPSFVMYKMIATFIGAEYVGVPLNDDFQIDAQTTLDAIKRHQPALVFIAQPNNPTGNLFDDETLRQIVAASPGLVVIDEAYTAFTNADYMSWVSEYDNVVVMRTFSKVGLAGLRFGMLFGAQEWIEQLNKVRLPYNINCLTQNAVLTAIRHFPEFVKQTEALREQRSWLSAQLDGVAGVTVYPSEANFILVRVDLPAKSVFSEMKRRGVLIKLLDGGHPKLAGCLRLTVGSHEENEAMLKALSGALAAVRG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SOHB_HAEIN
Sequence: MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLLRDFNLSEEEQKQRTKAEKKAEKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASETTALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQLSRLKQKGIKLTVAVDKVAASGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLGENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTSDDLILEKMKEKQVLNVKYRLKKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY
What is the function of this protein?
Possible protease.
What are the official names of this protein?
Probable protease SohB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACDH1_PARP8
Sequence: MKRKLKVAIIGSGNIGTDLMIKILRHGEHIEMGAMVGIDAASDGLQRAARLGVVTTHEGVEGLSRMPVFADIDIVFDATSASAHTRNDAFLRAIKPGIRFVDLTPAAIGPYCIPVVNGERHLDAPNVNMVTCGGQATIPMVAAVSRVARVRYAEIVASISSRSAGPGTRANIDEFTETTSRAIEVVGGAAVGKAIIVLNPAEPPLIMRDTVYTLSEFVDERQIEESVTRMAEAVQTYVPGYRLKQRVQFDRIDADGPIRIPGISDRMVGLKTSIYLEIEGAAHYLPAYAGNLDIMTSAAKVTAEGVANRLLANKK
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y4IH_SINFN
Sequence: MKTMVAMLLAAVGVAVSASSTLAVNFCQSNKDRNCFTGSFGLVDIPGDASHKLLKADFGYVDLNGVGWQTNKETKTDGASIPPLLQPFVGSPWEDGYIRAAVIHDWYCDRHVRTWKETHRVFYDTMLASGLEKPKAKLLFYAVYAFGPRWGYLVPGEKCAAGKNCIQMTGKDAAFVQLPGELADQSSAGELKAIKATIDLKERSGDALTLDELMAIADEAHPKQTLRDQRPAGGDEITK
What are the official names of this protein?
Uncharacterized protein y4iH.
Protein: APD_BOMPA
Sequence: GNRPVYIPPPRPPHPRL
What is the function of this protein?
Antibacterial peptide active against Gram-negative bacteria.
What are the official names of this protein?
Apidaecin.
What is the protein family that this protein belongs to?
Belongs to the apidaecin family.
Protein: APAG_BRUSU
Sequence: MYSAVTRGIEVTVEPFYLEVQSEPEENRYVWGYRVTIVNNSSETVQLCSRYWQITDANGHVQEVRGSGVVGEQPVLDPGASYQYSSGCPLTTSSGVMVGRYQMKGEDGAQFEIEIPAFSLDVPEQRRTLN
What are the official names of this protein?
Protein ApaG.
Protein: NORR_ECO27
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYNFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEVAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: ENV_FSVGA
Sequence: MESPTHPKPSKDKTLSWNLVFLVGILFTIDIGMANPSPHQVYNVTWTITNLVTGTKANATSMLGTLTDAFPTMYFDLCDIIGNTWNPSDQEPFPGYGCDQPMRRWQQRNTPFYVCPGHANRKQCGGPQDGFCAVWGCETTGETYWRPTSSWDYITVKKGVTQGIYQCSGGGWCGPCYDKAVHSSTTGASEGGRCNPLILQFTQKGRQTSWDGPKSWGLRLYRSGYDPIALFSVSRQVMTITPPQAMGPNLVLPDQKPPSRQSQIESRVTPHHSQGNGGTPGITLVNASIAPLSTPVTPASPKRIGTGDRLINLVQGTYLALNATDPNRTKDCWLCLVSRPPYYEGIAILGNYSNQTNPPPSCLSIPQHKLTISEVSGQGLCIGTVPKTHQALCNETQQGHTGAHYLAAPNGTYWACNTGLTPCISMAVLNWTSDFCVLIELWPRVTYHQPEYVYTHFAKAARFRREPISLTVALMLGGLTVGGIAAGVGTGTKALIETAQFRQLQMAMHTDIQALEESISALEKSLTSLSEVVLQNRRGLDILFLQEGGLCAALKEECCFYADHTGLVRDNMAKLRERLKQRQQLFDSQQGWFEGWFNKSPWFTTLISSIMGPLLILLLILLFGPCILNRLVQFVKDRISVVQALILTQQYQQIKQYDPDRP
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: MTND_BOVIN
Sequence: MVEAWYMDEAADDPRLPHRAEPARPVGLEQLRRLGVLYWKLDADKYENDPELEKIRKERNYSWVDIITISKDKLPNYEEKIKMFFEEHLHLDEEIRYILDGSGYFDVRDQEDRWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGDPVWTPYNRPSDHLEARTQYLEFLAQSA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.  Also down-regulates cell migration mediated by MMP14.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
Protein: RL31_DICTD
Sequence: MKKGIHPELKKAKIVCACGAVYETLSTKEYMTVEICSKCHPFFTGQRKFVDTEGRVERFTKKYNWEIK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HDOX_LISIN
Sequence: MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3456_SHESM
Sequence: MKIVGDSEHFKQPYDSDEEYVSKTEDKRDCEAAQKVGMELVSLSKTQLDKIELDEHLYDSIQQAHKIKPKTEAYRRHMQYIGKLMRHVDVEPIKAALAVVLNKNSNETAKLQIFEKMRERLLSQGDSEIQTLVEHYPQLDRQKLRTLVRQATKELAKGPESKSSKELFKYLRSEIQD
What are the official names of this protein?
UPF0307 protein Shewmr4_3456.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: DNAA_STRP4
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_SACHY
Sequence: MPRSRINGNFIDKTFSIVANILLQIIPTTSGEKRAFTYYRDGMLAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: APC5_HUMAN
Sequence: MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5.
What is the protein family that this protein belongs to?
Belongs to the APC5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: DNAJ_HAES1
Sequence: MAKRDYYEILGVQKGADDKEIKRAYKRLAMKYHPDRTKGDKESEEKFKEINEAYEVLADKEKRAMYDQYGHAAFEQGGGAGGFGGFSGADFGDIFGDMFGDIFGGGRSRQRVVRGEDLRYDIEISLEEAVKGCKKDIQINTLVHCGTCHGSGAEAGSKIESCPTCHGAGRVRRQQSFFVTEQTCPHCHGTGKKIEKPCHTCHGEGRVHKTQNLTVTIPMGVDTGNQLRLAGKGAAGENGAPAGDLYVVIHVKKHHIFERDGNNLYCEVPISFTMAALGGEVEIPTLDGRLKVKIPAETQTGKLLRLRGKGITSRGYAGDLICEIVIETPIKLNEEQKELLRKLEESLEGKTLQRPKSSGFLDGVKKFFDNLGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SHIDS
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDCKGMVNNKFNYFIMNKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: YAAI_ECO27
Sequence: MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSTDHGDLQLSGASVYFKATRSASQTLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: RR3_BUXMI
Sequence: MGQKINPLGFRLGTTQGHHSLWFAQPKSYSEGLQEDQKIRDCIKNYVQKNMRISSGAEGIARIEIQKRIDLIQVIIYMGFPKLLIEGRPRGVEELQINVQKEFNSVNRKLNIAITRIAKPYGQPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQIQIAGRIDGKEIARVEWIREGRVPLQTIRAKIYYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IF2_MYCTU
Sequence: MAAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEAPVARRLRESFGGSKPAPAKGTAKSPGKGPDKSLDKALDAAIDMAAGNGKATAAPAKAADSGGAAIVSPTTPAAPEPPTAVPPSPQAPHPGMAPGARPGPVPKPGIRTPRVGNNPFSSAQPADRPIPRPPAPRPGTARPGVPRPGASPGSMPPRPGGAVGGARPPRPGAPRPGGRPGAPGAGRSDAGGGNYRGGGVGAAPGTGFRGRPGGGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFADKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFDLSYGEDEGGEEDLQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVAVDLDGSQRLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVPEEFGGDTMFVDISAKQGTNIEALEEAVLLTADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLVQRGTLRVGDSVVAGDAYGRVRRMVDEHGEDVEVALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVVLRVIDRGVGGITETNVNLASASDAVIIGFNVRAEGKATELASREGVEIRYYSVIYQAIDEIEQALRGLLKPIYEENQLGRAEIRALFRSSKVGLIAGCLVTSGVMRRNAKARLLRDNIVVAENLSIASLRREKDDVTEVRDGFECGLTLGYADIKEGDVIESYELVQKERA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_STRZP
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNRDTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGGFKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKLDEVVDALVLYDQTQKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SHEDO
Sequence: MAKTSMKAREAKRAQLVTKYAEKRLALKAIISAPATSEEDRWDAVLKLQALPRDSSLSRKRNRCSQTGRPHGFLRKFGLSRIKLREATMRGEVPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: AF1Q_MOUSE
Sequence: MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTPTYESKDSSSVGKMNGQASGTEQKNPEGDPLLEYSTFNFWRAPIASIHSVDLDLL
What is the function of this protein?
Cofactor for the transcription factor TCF7.  Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T-cell fate.
What are the official names of this protein?
Protein AF1q.
What is the protein family that this protein belongs to?
Belongs to the MLLT11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Continuous nuclear export is followed by degradation.