PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_ALKOO
Sequence: MAKAIMVQGTMSNAGKSIITAGLCRIFAQDGYKVAPFKSQNMALNSYITKDGLEMGRAQVVQAEASYKEPDVRMNPILLKPTSNRTSQVIVNGEILGNMPAGDYFKYKTKLIPDIMKAYNSLAEENDIIVIEGAGSPAEINLKQEDIVNMGMAKLAKAPVLIAGDIDQGGVFASLYGTYMLQSEEEKQYIKGTIINKFRGDLKILEPGLKMLEDLIHIPTLGVVPYMDIDIDDEDSLSDRFSNKNSGGDVDIVVIRLPRISNFTDFNVFEYMEGVSVRYITKPSQLKNPDLVILPGTKNTLGDLKWLRESGLEASILKYAAEGKPVFGICGGYQMLGKTLKDPWHVEEGGEISGLGLINAETVFEREKTRSRVKGQFHHLSGIFEGLNHKIFEGYEIHMGITTPLGGEAFTSSLEAMDGGVKSDGLCSNNIYGTYVHGIFDEGQVAETIIRTLMEKKGLVYEPNKNFNMVEYKNKEYDKLADALRKALDMEAIYRILNEGI
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SLX11_TRYCC
Sequence: MDTRFHCVYLLTSLDPQCAGEYYIGYTVDPIRRLRQHNGEIVSGAWRTKRRGRPWELLCCVSGFGEDRIALKFEWCWQHPTKSTRLKTQMTQLRGVHRLPYAVGVLHLLLRADLFARLQLTLHIFEPERVGRVVAELQGRVPSISPLVATSLLRIEEITKERFMSLYLDGVSGDGTAGDGCVYFVTAPLSSQPDVDAPSRRVRSCRYLSEEDVFRQHARVKELLEANQCPCALCSLPLRSPYFVRCYRTPFCALRAHLACLAMWFTYETMQKRDVTMGQSTRNERSGEYSNKIKDDSNDGTMDAHASGRQLHSLSVNNADFSSSRDAGSILDSSGHISAFEESRCASSPSLTLLPCQPCPCPLCDEPLQWGALVHDLKRRAVLEKRWMERQRREKIEAALAERLQRLQNSSLTERKSRRKATPALGQKRNRGEYCGDTVGDGGKEAVTNWRARAMDGCDSWNDTNDFSHSVSLPPSRDEGYACDSSRRGVGGSKHTTRMTDEGKNDSITDICDCVLQLTEFNLDEWLDA
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FEOB_SALTY
Sequence: MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFATTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQQVRIDVDALSTRLGCPVVPLVSTRGRGIEALKLAIDRHNANDNVELVHYAQPLLREADFLADAMAQEMPLQQRRWLGLQMLEGDIYSRAYAGEAAQNLDTSLARLKDEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTRAVDKIILNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDAGSVAIFIHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVLGIVMAVLTGLMLKHTIMRGEASPFVMELPVYHVPHIKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEAFNPADFHLGDELLGAVDDTWQSLKDTFSLSVLANPIEASKGDGEMATGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVTSFSQHPTYSLICILAVIVFNVVVLSLLRRARSRVDIELLATRKNVSSCCSGTAGNCH
What is the function of this protein?
Probable transporter for a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP18_NPVOP
Sequence: MAVKEVRLYLCPVPPSVALSVGDADADEPMIYFENITECLTDASCDKLACFAELKQEQALFMKKLYKHMVLKSDGAYNKHHVLFDLMVMYKTYVQLADESAFGSNVLHYCEQFITGAFEVFGLGSRVAVLVPPGWENDNLSVLLKHLHGLHLIAIDIVQ
What are the official names of this protein?
P18 protein.
Protein: COAA_PASMU
Sequence: MDLTNSTFLSNQLTPFLSFSREQWAELRKSVPLTLTEQDLKPLLGINEELSLDEVRTIYLPLVRLINYYIEERIQRQQVMNRFLGVNPDKVPYIISIAGSVAVGKSTSARILQSLLSQWPERRKVDLITTDGFLYPLAKLQQDNLLHKKGFPVSYDTARLVRFLADIKSGKPKVSAPVYSHLIYDIVPDQFDVVDQPDILILEGLNVLQTGDRSSQTFVSDFVDFSIYVDADEDLLKAWYISRFLKFRQSAFSDPNSYFKHYATLSEPEAISTAGRIWDEINGLNLRENILPTRERANLILTKGTDHAVELVKLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI023_YEAST
Sequence: MCYYLYYRGVSLVLIVTFLSSFIFIVWLPVALVSWFEFGLSSLSSVDDSSLAVLSLPAVFSSAASPDSCLVSLIEVKGEAFICVLELTFVLELTLGEDVLEGGCLLI
What are the official names of this protein?
Putative uncharacterized membrane protein YIR023C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRUA2_BACAN
Sequence: MNNYKLTIQYDGARFKGWQRLGNNDNTIQGKIESVISEMVGKETEIIGCSRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHDRFHARYNSKAKTYLYKIWNEEHTNPFMRKYSMHVNKKLNVKSMKEAAKHLVGSHDFTAFSNAKSKKKSMVREVYSLEVMEEAGFVQIRVSGNGFLHNMVRKIVGALIEVGLGQLAAEAIPQILEAKQRNQINCLAEASGLYLENVEF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 2, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 2, tRNA-uridine isomerase I 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ATP6_LEMCA
Sequence: MNENLFASFITPTIVGIPIVILIIMTPYIIFPSPTRLINNRLTSLQQWLVQLILKQLMSIHNTKGRTWSLMLISLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAATVIKGFRHKTKASLAHFLPQGTPIPLIPMLVIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLTSISPATASITFIILTLLTILEFAVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FLOA_LISIN
Sequence: MTMIGPIIIAVLIIIFLIVFFTLVPVGLWISALSARVPVGLGTLIGMRLRRVVPSRVVKPLIKAVKAGLDLEVNQLESHYLAGGDVDNTVDALIAAHRANIELDFSRAAAIDLAGRDVLEAVQTSVTPKVIRTPEFTGVAQNGVEVKVITQITVQSNIERIVGGAGEDTVIARVGEAVVSTVGETREHTDVLENPNSISKKVQEQGLGDGTAYTILSIDIAEMRIGDNIKAKLDIEKANADMEVAQAAASKRKAEAIALEQENRAAVVAAEAEVPRALSRALEEGNLGVMDYYKMENVQSDTAMRESIAHEDEK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: EI3D2_DROER
Sequence: MSNYAPFIKPYVEYNEHGWGPCEVPELDVPYQPFCKGDRLGKICDWTVSLPEKKFPSKYASTFGNSSQYAYFYEDDDSTFHLVDTTGSKAFKPYQRGRYRPNVRNNVRARGRTGRGSQAVGGPGGPAAGGSTANSTKYGKGRNTRNTQNVGRRFGRSAPTRLRESSVMVQSDWVSIEEIDFARLLKLALPNIKEGKDIATCGSLEYYDKLYDRVNLRNEKPLLKMDRVVHTVTTTDDPVIRRLSKTMGNVFATDEILATIMCCTRSNYSWDVVIEKLGTKVFLDKRDNDQFDLLTVNETSLEPPMDEEGSINSAHSLAMEATLINHNFSQQVLRIGDQEPRFKFEEPNPFEEQGVDLASMGYRYRQWDLGNEVVLIARCKHNGVIQGPNGEMQFLSIKALNEWDSKGSNSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVLAGSDQLKLGYVSRVNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGVLRCLIDIVMKQPDGKYLIMKDPNKSMIRLYDIPENAFDSDCNDDTESSETFVHSNDN
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-2, eIF3d-2, Eukaryotic translation initiation factor 3 subunit 7-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_DICCI
Sequence: MKKEINMENLLYIIIEGGLKSLIVIIGLLIGVAFATLLERKVMAAMQKRRGPNVVGFVGLLQPLADGLKLVLKETIIPIVADKIIYAIAPILTFTISIVLWSVIAVGVQSVFASINSGVIFILAISSIGVYGIILAGWASNSKYAFLGGLRSAAQMVSYEVALGLIILSIITYAGTVNIQEIMENQEKVWFIVPLLPGFLLAFISALAETNRPPFDLPEAEAELVSGYNVEYSSTGFALFFLGEYANIILMSVLLSVFFLGGIVSNKISGAMKGVGMLCSFIWVRATLPRYRYDQLMYLGWKSLLPFALLIYIGVISMVLIIK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NCAP_PUUMB
Sequence: LQARQQTVSALEDKIADYKRRMADAVSRKKMDTKPTDPTGIEPDDHLKERSSLRYGNVLDVNAIDIEEPSGQTADWYTIGVYVIGFTLPIILKALYMLSTRGRQTVKENKGTRIRFKDDTSFEDINGIRRPKHLYVSMPTAQSTMKAEELTPGRFRTIVCGLFPTQIQVRNIMSPVMGVIGFSFFVKDWADRIREFMEKECPFIKPEVKPGTPAQEAEFLKRNKVYFMQRQDVLDKNHVADIDKLIDYAASGDPTSPDNIESPNAPWVFACAPDRCPPTCIYVAGMAELGAFFSILQDMRNTIMASKTVGTAEEKLKKKSSFYQSYLRRTQSMGIQLDQRIILLYMLEWGKEMVDH
What is the function of this protein?
Encapsidates the genome protecting it from nucleases (Probable).  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (Probable).  The nucleocapsid has a left-handed helical structure (By similarity).  As a trimer, specifically binds and acts as a chaperone to unwind the panhandle structure formed by the viral RNA (vRNA) termini (By similarity).  Involved in the transcription and replication initiation of vRNA by mediating primer annealing (By similarity).  Plays a role in cap snatching by sequestering capped RNAs in P bodies for use by the viral RdRp during transcription initiation (By similarity).  Substitutes for the cellular cap-binding complex (eIF4F) to preferentially facilitate the translation of capped mRNAs (By similarity).  Initiates the translation by specifically binding to the cap and 40S ribosomal subunit (By similarity).  Prevents the viral glycoprotein N (Gn) from autophagy-dependent breakdown maybe by blocking autophagosome formation (By similarity).  Inhibits host EIF2AK2/PKR dimerization to prevent PKR-induced translational shutdown in cells and thus the activation of the antiviral state (By similarity).  Also displays sequence-unspecific DNA endonuclease activity (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the hantavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host Golgi apparatus, host cis-Golgi network. Note=Internal protein of virus particle.
Protein: ATF1_MOUSE
Sequence: MEDSHKSNTTETASQPGSTVAGPHVSQIVHQVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGEGENPSISAITSMSVPAPIYQTSSGQYIAIAPNGALQLASPSTDGVQALQTLTMTNSSSTQQGTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLASQTTKTDDPQLRREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV
What is the function of this protein?
Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters.  Binds to the Tax-responsive element (TRE) of HTLV-I.  Mediates PKA-induced stimulation of CRE-reporter genes.  Represses the expression of FTH1 and other antioxidant detoxification genes.  Triggers cell proliferation and transformation (By similarity).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, TCR-ATF1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_ECO27
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYA_ECO24
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPS2_KLULA
Sequence: MTKQISKSTQYKPSKSTLVSAKLFSMNRTESTRLLDRAWSVLESGSDGYVYAKDIPEIISFIDRELPSKLTTQSNDKVIESWVNNDPMKTLSKEQFLEAFSMLVGTSFDTAVQIAMQSDILTPTRRGASLFGSYRRSSNDLEQVLPAEQIKALKRELQEWKDKYTFLEHEFQFFLSQEKKNPEVIDNTKHEFIISELNRKLREQDEAIEDLKSQLDYGLVPELKDKTNWIKALQRKAYNYLLPKILICLLLLLLYYCLAAKILFTKSSSTDDVPSFIRQQSWWERNKILSRIQWYFKDRIENNVVRNSSEVIQNYNSVFGIH
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
What are the official names of this protein?
Monopolar spindle protein 2.
What is the protein family that this protein belongs to?
Belongs to the MPS2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: RFTRM_RICTY
Sequence: MQYSIKQILNNANDKLNKIGINLPELEARILLQHVTNKPIEHLLIKLNEQLSEAEIEAFEKLLERRLEHEPIAYITGIKEFYSREFIVNKHVLIPRIDTEILIDVVIGLVVSRNDLNTCSKLKSLDSVKTIQHYNILELGTGSGCIAISLLCELPNTSVIATDISVDAIKVAKSNTIKHNVTDRIQIIHSNWFEKLNKQKFDLIVSNPPYISHSEKLEMAIETINYEPHIALFAEEDGLEAYSIIAKNAKQFLKPNGKIILEIGFSQAEKVCQIFLNYGYNIDHIYQDLQSHNRVIEISPINLNRSYARRIGKSLSKMQQKLLDNELPKYLFSKEKFASEKRKIFLEIGFGMGEHFINQAKINPDTLFIGVEVYLNGVANVLKHAAQHNIMNFLLFPNNLDLILNDLPNNSLDGIYILFPDPWIKNKKKKKRILNKERLNILQNKLKNNGNLVFASDIENYFYETITLIRQNGNFEIIHNDDYLKPHDNYIITKYHQKAINENRTAKFMILQHALTGH
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
Bifunctional methyltransferase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: FUR_LEGPN
Sequence: MEESQQLKDAGLKITLPRIKVLQILEQSRNHHLSAEAVYKALLESGEDVGLATVYRVLTQFEAAGLVSRHNFEGGHSVFELSQGEHHDHLVCVKCGRVEEFVDEIIEQRQKAIAERAHFKMTDHALNIYGICPQCQ
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB2_ANEPH
Sequence: TGTYRGDSETQLERVNVYYNEASCGRYVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMXTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLVTPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMRDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPVGLKMACTFIGNSTSIQEMFRRVRDQFTAMFRXKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEPEGXYEEDYDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CCA_ALKEH
Sequence: MKVYLVGGAVRDQLLGREVRERDWVVVGARPEDLKQRGYRPVGQDFPVFLHPETHEEYALARTERKTGRGYHGFAFHASPEVTLEQDLARRDLTINAMARADDGTLIDPYDGRRDLEQRLLRHVSPAFAEDPVRILRLARFAARFQPLGFRVAPETLALCRKMVADGEVDALVPERVWQELSRALLEDTPVPFFRVLRECGALARVLPELDRLFGIPEPEAYHPEGDTGEHTLLALAQSARLGGDLPVRWAVLLHDLGKATTPSQVWPRHPAHEHRGVPLVEALCERLRAPRECRDLARLVCRYHLQAHRAFELRASTLLKLLEGLDLFRRQARLEPFLLACEADARGRLGLEDQPYPQARFLREAYRVAAAVTARPFVQAGFKGRQIAEAVTRERIRALAALQRDYPRPEAH
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: FIS_YERPP
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: UXUA_ECO55
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAVRFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: M3_CONTE
Sequence: MSKLGALLIICLLLFPLTAVPMDGDQPADRPAERMQDDISFEQHPMFDATRRCCNAGFCRFGCTPCCY
What are the official names of this protein?
TxMMSK-03, Conotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNC_SHISS
Sequence: MQTIIRVEKLAKTFNQHQALHAVALNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLSVLENVLIGALGSTPFWRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRIEENAKAA
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GNA1_DICDI
Sequence: MSSIVDDGISFRPLDIDDFDKGYSECLQQLTEAKFTKEQFIERFNQIKKQSDTYFLIVAVDVKLNKIIACGSLFVEKKFIRNCGKCGHIEDIVVNNNYRGKNLGLRIIEQLKCIGSQAGCYKIILDCSEANVKFYEKCKFERKGVQMSIYLPTPPKL
What are the official names of this protein?
Glucosamine 6-phosphate N-acetyltransferase 1, GNPNAT1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNA1 subfamily.
Protein: RL5_CLOP1
Sequence: MNRLQERYEKEVVPAMMEKFGYKNIMQVPKIEKVVINMGVGEAKDNPKVLESAVSDLQIIAGQKPVLTRAKKSVANFKIRENMALGCKVTLRKTNMYEFVDKLVSIALPRVRDFRGVSAKAFDGRGNYSLGIKEQLIFPEIEYDKVDKVRGMDIIFVTSANTDEEARELLRFLGMPFAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL3_RICRS
Sequence: MRTGIIAQKIGMTSVFNDKGERISLTLVKVDDCQVVGHKTLEKHGYNALVIGVKDKKISRVTKPMRQVFANAKISPKTKLKEFRISEENFIDIAASLEVDHFTAGQFVDITATTIGKGFAGSMKRHNFRGLEASHGVSISHRSHGSTGQRQDPGKVFKGKKMAGHMGCNQVTIQNLKIFAVDKERKLIMIQGSIPGHKNSYLSVKDAIKKISITV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.