PharMolix/UniProtQA huggingface dataset:
Protein: DGAT2_XENLA
Sequence: MKTIIAAYSGVLRGTGSSLLSAVHDLPSIPWLSKSSVVRHLQIISVLQWVLSFLILGVACTAVLVYIFCTDLWLIAALYFTWMVLDWNTPYKGGRRSSWVRNWAVWRYFRDYFPVKLVKTHNLLPSRNYIFGYHPHGIMCLGAFCNFGTEATGVSKKFPGIKCHLATLAGNFRMPVLREYLMSGGICPVNRDTINYILSKNGTGNAVVIAVGGAAESLNCRPGKNTVTLLHRKGFVKVALQHGADLVPIYSFGENETYKQVVFEEGSWGRWIQQKFQKYVGFAPCLFHGCSFFSSNSWGLVPYANPITTVVGEPITVPKIEQPTQKDVELYHSMYLSSLHRLFDKYKTKLGLPDSETLEFI
What is the function of this protein?
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Required for synthesis and storage of intracellular triglycerides.  Probably plays a central role in cytosolic lipid accumulation (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Cytoplasm, perinuclear region.
Protein: ILVC_DICT6
Sequence: MAKIYHDLEVSLEVLSDKVITIIGYGSQGRAHALNLKDSGMKVIVAVRPNGESWKRALEEGMTVEKIEDAVQKSDIIMFLIPDTEQPAIYKEKVLPYLRPNQALGFAHGFNIHFSQIVPPPFVDVFMVAPKGPGPLVRDLYVEGKGVPALFAVYQDYTQKCRDIALAYAKGIGATRAGVLETTFKEETETDLFGEQVVLCGGVTALIKAGFETLVEAGYQPEVAYYECLHEMKLIVDLINQGGISFMRKAISDTAKYGDVTRGPRIVNEETKKEMKKILNEIQNGQFAKEWILENQVGRPVFNALLKKDEDHLIEKVGKVIREMMPWLKPKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PR1F4_ARATH
Sequence: MANNDEITTSSHASPAVNHESISRAKQRIKDGLATRRSWRVMFDLHSTGLPHGVSDVFSRIKTNLAYFRSNYAIVILNVIFFSLIWHPTSLIVFTGLVFLWIFLYFLRDVPLKVFRFQIDDRAVLIGLSVITIVLLLLTNATFNIVAALMAGAVLVLIHAVIRKTDDLFLDEEAATTETSGLTSHPSS
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein F4, AtPRA1.F4.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: EFP_STRZT
Sequence: MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_RICAE
Sequence: MPELKIKTEKVEKQLTKEPLVLKTPKEKIDNLGKFYATGKRKNAIARVWLKVGKGKIVVNKKTIAQYFPSETYVKTILKPFVLTKTIDQYDIICTVRGGGISGQKGAILHGISKALDKSAPDFHAILRKGGLLTRDSRVVERKKYGQRKARKKTQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: EX7L_OCEIH
Sequence: MKDKYLTVTALTKYVKRKMDSDPHLRDIWLRGEISNFKHHSRGHMYLTIKDDSARIQAVMFASSNRKLLFHPENGMNVLIRGEISVFEAYGQYQLYIHEMEPDGIGSLYQAFEQLKERLHKQGYFADEYKKPIPRYPKNIAVITSPTGAAIRDILTTMKRRYPSVKITVFPVLVQGNQAKASIARSIQQADSLSYDVIIVGRGGGSIEELWSFNEEEVARAIFESKTPIISAVGHETDTTISDFVADLRAPTPTAAGELAVPSQVELLDKIEIQKRQLARLLKQYISQHETILHQLRQTYAFKYPHQLVKQKEQELDSTMDNLQRRMKSKVSDDKLTHNHLIKRLSSQHPQRELRLAIDKLRQLHSLQNKMMNNYLEQQSQRLYSQIDKLSLVNPLEIMKRGYALPYNEDGALIKSVKHLHINDTIQLRIADGEVTGKVTAIKEANENGNEGSNV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO5_THEON
Sequence: MAAKKEFDIFTHELVPEHRILSEEEKEELLRKYRIKISQLPQIKASDPAVVALGAKPGDVLEIKRKSPTAGYYYYYRLVVED
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCO2_MOUSE
Sequence: MLLALGPKAWPKLSQFKPLLRISGGETLHRNSRHWAGQGQRQGPGLRTRLLITALFGAGLGWAWLAARAEKEQWRQQQRTEALRQAAVGQGDFSLLDHKGQPRCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRKLEAEPDLPLVQPVFITVDPERDDVAAMARYVQEFHPRLLGLTGSTEQVAHASRNYRVYYSAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQIVESIRRHIAAFHSVLP
What is the function of this protein?
Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2).  Involved in transporting copper to the Cu(A) site on MT-CO2/COX2.  Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
What are the official names of this protein?
Protein SCO2 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: UBIG_XANOP
Sequence: MNSNTQPASGNFHQSELDKFAALANRWWDADGPQKPLHALNPVRLDYVSARLDLAGARVLDVGCGGGLLSESMARLGAQVTAIDLAPELVKVARLHGLESSVQVDYRVQSVEDLAAEQTGSFDAVTCMEMLEHVPDPTAIIRACARLLKPGGKLFLSTLNRTPAAFALAVVGAEYIARLLPRGTHHYKDFIKPAELAAWLRNAELQLEDVSGMLYEPWRNRARLSSRTEVNYLAYAVKP
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: NDHK_MARPO
Sequence: MVLNFKFFTCENSLEDNSTTMLKNSIESSFINKTLTNSIILTTFNDFSNWARLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYTTVRGVDKLIPVDIYLPGCPPKPEAIIDAIIKLRKKIAQEIYEEKKILKKGTRFFTLNHQFNFFSNLDNPKLTSSNQFFQSKKTSKVLLETSLTFKEKENL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PPK1_MYCLE
Sequence: MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDLDQAERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTSAGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYHSFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVYGIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVRSILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQKGQQVRDHQESLMERHRSR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: FBRL_DEBHA
Sequence: MAFGAPRGRGGDRGGFGGRGGSRGGFGGARGGRGGSRGGFGGDRGGRGGSRGGFGGDRGGRGGRGGPRGGARGGRGGARGGARGGAKVVIEPHRHAGVFIARGKEDLLVTRNIAPGESVYGEKRISIEEPSKEEGAAPTKIEYRVWNPFRSKLAAGIMGGIDELGIAPGKKVLYLGAASGTSVSHVADVVGPEGMVYAVEFSHRPGRELIGMAKKRPNVIPIIDDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHLFLKDQGTVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYVRSGLKK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: MYG2_STEAT
Sequence: MGLSDGEWQLVLNVWGKVEADLAGHGQDVLIRLFKGHPETLEKFDKFKHLKTEADMKASEDLKKHGNTVLTALGAILKKKGHHDAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPAEFGADAQAAMNKALELFRKDIATKYKELGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin-2.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: B2MG_AOTLE
Sequence: MARFVVVALLVLLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTLSTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_LEVBA
Sequence: MAIKKYKPTSNGRRNMTSLVYKDVITKTTPEKSLLDSQSHSAGRNNAGKMTVRHRGGGNKRQYRIIDFKRIKDDVPATVKAIEYDPNRTANIALLVYADGVKSYIIAPKGLKVGDKVQSGPEADIKTGNALPLKNIPFGTVIHNIELKPGKGGQLVRSAGTSAQLLGKANDEKYVLVRLSSGEVRMVLSVNRATIGAVGNEEHELVNVGKAGRTRWAGQRPHVRGSVMNPNDHPHGGGEGKAPVGLPSPLSPWGKKTVGKKTRSKKNKTEKFIVRHRKGSKM
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PNPA_PSEWB
Sequence: METLDGVVVVGGGPVGLLTALKLGKAGIKVVVLEAEPGVSPSPRAVAYMPPTAAALDRFGLLQDIRKRAVMCPDFAYRHGNGELIAKMDWSVLSQDTQYPYMLLLGQNHVSNVIFQHLRELPNVEIRWNHRVEEVDQDDAYVTIETSSPGGTSRLRARWLAATDGARSTVRQKIGLTFDGITWDERLVATNVFYDFSLHGYSRANFVHDPVDWAVVVQLDKTGLWRVCYGEDASLSDAEVRRRLPERFKRLLPGAPTPDQYRVDHLNPYRVHQRCAAEFRRGRVVLAGDAAHATNPMGGLGLSGGVLDAEHLAEALIAVIKNGASTKTLDEYSIDRRKVFLEFTSPTATANFTWMKESDPAQRIRDDAMFKEAGTDRAVMRQFLLDLEKLNGRRVIEKKLKAA
What is the function of this protein?
Involved in the degradation of para-nitrophenol (4-NP).  Catalyzes oxidation of 4-nitrophenol (4-NP) at position 4 with concomitant removal of the nitro group as nitrite and production of para-benzoquinone.
What are the official names of this protein?
Para-nitrophenol 4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: HBOH_BURP0
Sequence: MTAIRGGSRRAPGLALALLGGVLLGACHGDENAQVNALPGFVSGSVRKTAYDGASDDLLTAGLGKTGLGSDTRPGFANPAQPSAAELRRLAIYSNYRALVDITPNGGYGRFWGPNVDLAGNDTLGEGKIAGTEYLAYSDDGSGRKNVTLLVQVPASFDPANPCIVTATASGSRGVYGAIAAAGEWGLKRGCAVAYNDKGGGNGAHEIGTGVVTLIDGTLATASSAGSSSLFTASESSSTLAAFNSAFPNRYAYKHAHSQQNPEQDWGRVTLQAVEFAYWALNEQFGPVVDGTRHGIRYRPGDITTIAASVSNGGGSALAAAEQDTRGWITAVVVGEPQINVRMTPGVTVEQGGAPVPSFGRPLADYATLANLLQPCAAAAVAATGAPYLSALPMGVTQSIRTQRCATLAAAGLVSGADTASQASDALAQLHAAGYLADSDLLQAPMWDSQAMPAIAVTYANAYTRSRVTDNLCNFSFATTNPVTGAVAAPAVSPMTNLFGAGNGVPPTNGINLVFNGASGGVDHRLATPDASFAGAFCLRQLWAANQLGIGTNVDAVRVAANLQHKPAIIVHGRSDALVPVNHASRAYVAQNSATEGRASQLSFYEVTNGQHFDAFLSVPGFDTRFVPVHYYDEQALNLMWNHLKSGAPLPPSQVIRTVPRGGVPGAAPALSTANLPPIVQSPGANAIAVNAGVIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: HYPA_DEHMC
Sequence: MHELSITEELLKTIVAKAEEAKARNVSRINLVIGEYAGVVEDSVKMCFEILSQDTIANGAVLEFSRIPAKFRCRLCGHTFPSGQNLLVCPECQGWNAEVIAGNEFFIESIEVDDESQSS
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: VIUB_VIBCH
Sequence: MSNEVERVYPRLLDFVRKKYVSKNLLRVTLTGEDLIGFPEDQNGSHIKVFFPNQASGILQLPIREGDKVIWPEHKPVPRAYTVRQYRAQSNELDIDFVVHGEGTPGGGWALKAQTGSQLGLIGPGGPDPLIEPADWHIMAGDLSAVPAISAILEKMPSQAKGYVFLEVDDIEDKHDISHPEQMVIKWLVRDPNQAQPVLAMAIEQLPVPQGAESLSAFVAGENESVIACRKILRNEYRIARDKIYAIPYWKRGKNEEAYHEERHVVMDEEF
What is the function of this protein?
Involved in intracellular removal of iron from iron-vibriobactin complex.  Vibriobactin is an iron-chelating compound involved in the transport of iron from the bacterial environment into the cell cytoplasm (By similarity).
What are the official names of this protein?
Vibriobactin utilization protein ViuB.
What is the protein family that this protein belongs to?
Belongs to the SIP oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ROSS1
Sequence: MASKKGNRIIIKLRSTESAHTYTTTKNRKNDPNRLELRRYDPTLRRHVIYRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CXL16_RAT
Sequence: MRRGFGPLALTLFLFFFALLTLPGDGNQGSVAGSCYCDRTIPSGTQIPPATLNHMRKYLKTFHRCQFFIRFQLQSKSVCGGSQDQWVRELVNCFEHKQCGIGHGQSFHHQKHVPQASTRIPEATEGKPPDTSTAVQFQSTQQSTFPSGAPSLNKELTRHWETTILPSGYGLEARPVAEANEKQHKQQKEPGAGAGTQALVPVLSLLAIVFFLVAAMVCVLCNRRVTRQSSSGLQLCYTPVEPRPQGL
What is the function of this protein?
Induces a strong chemotactic response.  Induces calcium mobilization.  Binds to CXCR6/Bonzo.  Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity).
What are the official names of this protein?
C-X-C motif chemokine 16, Small-inducible cytokine B16, Transmembrane chemokine CXCL16.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BXB9_BOMMO
Sequence: MMKTAVMFILVVVISLTYSSEEQEVARTYCGRHLANILAYVCFGVEKRGGAQYAPYWQETYLRSRKEPGVVDECCFRPCKLEVLKSYCGV
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin B-9, BBX-B9, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LETM1_RAT
Sequence: MASILLRSCRGRGPARLASPRAASPRGSLRDRACLSCTRTVGLTSHESVLSRCCTPANPVYLYFKSEPLSCWTQRPECQGTVARAAWTPASARLVVTGPQYLPVRGWHSSSPLGEDSMIEKSLKSLKDKNKKLEEGGPVYSPPAQVVVKKSLGQKILDELKHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATKDFSAFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEHLEELKRAAETAKDIQPEVAEATVPGRPGAELQPKMVDVIPPSEILKDTAPVLEGLKGEEITKEEIDILSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYIEESTASKRLSKRVQQMIGQIDGLITQLETTQQNGKLDPAAASSPTGESVISVDELISAMKQIKHIPEHKLISLTSALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKVEEKEKAKEKAEKEAAEVKN
What is the function of this protein?
Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (By similarity).  Mediates proton-dependent calcium efflux from mitochondrion (By similarity).  Functions also as an electroneutral mitochondrial proton/potassium exchanger (By similarity).  Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (By similarity).  Required for the maintenance of the tubular shape and cristae organization (By similarity).  Essential for early embryonic development (By similarity).
What are the official names of this protein?
Mitochondrial proton/calcium exchanger protein, Electroneutral mitochondrial K(+)/H(+)exchanger, KHE, Leucine zipper-EF-hand-containing transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the LETM1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ABND_EMENI
Sequence: MVHITLPGLLLCLCLYLSVAPANPLNAHARVSDTTAFPLPNEGHVVAHDPSIVRHHEHFYLFKGGIHIPVFRASNLSGPWERLGTVLNGPSLVQKQNQRRPWAPMVTQWKNRFYCFYSISQNGKRNSAIGVASSDSVEPGGWTDHGPLINTGHGPGSGVYPFNVSNAIDPAFFADPITGQPYLQYGSYWKGIFQVPLAEDLLSVENATHPNTDHLVFLPKKKPKPNEGVFMSYRAPYYYAWFSHGQCCHFKTQGFPKEGNEYSIRVGRSTSVHGPFVDRDNKDLLNGGGSVVYGSNHGKVYAPGGLGVLPGANGEPDVLYYHYHNASIGFAQGDARLGWNYLDYVDGWPVPRAPSNPGNSLQPPSSVSLQIVAFLCLVILFTL
What is the function of this protein?
Endo-1,5-alpha-L-arabinanase involved in degradation of pectin.  Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
What are the official names of this protein?
Probable arabinan endo-1,5-alpha-L-arabinosidase D, Endo-1,5-alpha-L-arabinanase D, ABN D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MTAP_PYRHO
Sequence: MPKIGIIGGSGVYGVFEPKEVVKVHTPYGRPSAPIEIGEIEGVEVAFIPRHGKYHEFPPHQVPYRANIWALHELGVERVIAINAVGSLKEEYKPGDIVIIDQFIDFTKKREYTFYNGPKVAHVSMADPFCPELRKIFIETAKELNLPVHERGTYVCIEGPRFSTRAESRMFRQFADVIGMTLVPEVNLARELGMCYVNISTVTDYDVWAEKPVDAQEVLRVMKENEEKVQKLLKRAIPKIPEERKCGCADVLKTMFV
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: VE5_BPV2
Sequence: MPNLWFLLFLGLVAAMQLLLLLFLLLFFLVYWDHFECSCTGLPF
What is the function of this protein?
E5 can induce cellular DNA synthesis.  It seems to interact with a 16 kDa cellular protein.  E5 seems to activate the PDGF receptor (By similarity).
What are the official names of this protein?
Protein E5.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E5 protein family.
What are the subcellular locations of this protein?
Host membrane; Peripheral membrane protein.
Protein: PYRR_BACC0
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEIEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.