PharMolix/UniProtQA huggingface dataset:
Protein: PNP_PSET1
Sequence: MQAIIKEFQLGQHTVTLETGAIARQADGAVLASIGDTSVLVTVVGKREAQPGQDFFPLTVNYQERMYAAGRIPGGFLKREGRPNDGETLIARLIDRPIRPLFPSGFVNEVQVIATVVSVNPEIQPDMVALIGTSAALAISGIPFSGPIGATRVGYIDGEYVLNPTLKELEESKLDLVVAGTDNAVLMVESEADVLAEDIMLGAVVYGHEQAQAIITAIKEFKAEAGKPTWDWTAPAKNVSLEEKVASIAADKVGEAYRITDKVARKEALGVAKDEVVAVLTSELAEGESLDKQEIGKIFGSLEKKIVRGRIAAGEKRIDGREPDMIRALDVMTGVLPRTHGSAIFTRGETQALVTATLGTERDSQLIDDLTGTHKNHFMLNYNFPPFCVGETGFVGSPKRREIGHGNLAKRGIAAVMPTLTEFPYSIRVVSEITESNGSSSMASVCGTSLALMNAGVPIKASVAGIAMGLVKEDDKFVVLSDILGDEDHLGDMDFKVAGTAGGITALQMDIKIEGITQEIMQIALKQAKAARLHILEVMDKAISAPSEELSQFAPRIYTMKIPQKKIAEVIGKGGATIRQLTEETGTTIEIGDDGTIKIAATDGESAANAISRIEQLTAELEVGTIYEGKVVRIVDFGAFVNILPGKDGLVHISQISTERVNNVTDHLSEGQEVKVKVLEVDRQGRVRLSIKEAMESAAPAADAPTDA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4944_POLNA
Sequence: MELLRLAILFAVTALAEIVGCYLPWLVLKQGKSLLLLVPAAMSLGLFAWLLTLHPSAAGRTYAAYGGMYIAVALGWLRFVDGIALTRWDLSGAAIALVGMAVIVMQPSTT
What are the official names of this protein?
UPF0060 membrane protein Pnap_4944.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_BAUCH
Sequence: MIPIIALVGRPNVGKSTLFNKLTHTNDAIVADYSGLTRDRKYGHAKWKNYNFIVIDTGGIGISKKGLAIHIIKQSLLAIKEADVIFFVVDAITGLMIEDQSIAKYLRKLQKPTFIIINKIDGIDITQVKLQFYAINIGQIFPIAALQGRGINILLKAVFLSLIQNNIPLTNNSFTESTKYIDQLLMPIKLAIVGSSNVGKSTLANSFLGEERVVVFDMPGTTRDSTYIPMIRAEREYVLIDTAGLRKRSKITDIAEKLSTVKTLQSIEESNVVLLVLDAHKGISDQDLSLLSLIIDSGRAFVIVVNKWDNLSIERRNSIKDTLAYRLSFINFARIHFISALYGTNIDQIFQSVNEAYHCSTKRISTALLTKILHIAIKEHQPPIISGYRVKLKYAHYGGYNPPIVVIHGNKATELPVSYKRYLSNFFRHSLQIMGTPIRIQFNEPANPFIHHKSIPNKLRKLLLSKRNIKIK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GPMI_MESFL
Sequence: MNVKKPVILAILDGWGIEEAGVGNAVANADQKFVKEMMGMYPWVKAHASGEWVGLPEGQMGNSEVGHIHLGAGRINMESLAKLNHEVKVDGFLTNEVLVDTFKYVKEHNSALHLMGLFSDGGVHSHMNHMISMYKAAVKFGLTNIKFDLITDGRDTAPKVAEQYINQLLQVIKDNNNIGEIASISGRYFAMDRDKRFERSAAAYITMTERKVDQPKFTDPIEYVKAAYENGLDDEMIVPAYNASVVDSELKANDAMIFTNFRPDRAIQMASIMTNNNYPAWNDEAFKDVEFIGDKIRFVSTMKYADSVTSQFIAYPPTPLTNTLGEYISSLGLKQLRIAETEKIAHVTFFFDGGNDYFKNGLAKPEEISLPHASIDLISSPKVATYDLKPEMSAVEITDKLLEEVKKDEFDLIVLNFANCDMVGHTGNNDATVKGVKVLDEQLKRIHDEFVLKHNGVMVITADHGNAEIMIDETGGPNKKHTTSLVPIIVTDKTIELSDFDPAIAKVAPTILDIMGLEIPKEMTQPSMIIKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PVK1_EUBDI
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, EubDi-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBA_POGSC
Sequence: MSLSDKDKSAVKALWSKINKSADVIGNDAVSRMIVVYPQTKTYFAHWPDLTPGSTHIKAHGKKVMGGIALAVSKIDDLKAGLSNLSEQHAFKLRVDPANFKILNHCIMVVISSMFPKDFTPEAHVSLDKFLSAVALALAEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GERQA_BACCE
Sequence: MKPYGKIPDNSIKSLQDLMQLLKKSKDFITLEIASNNSSIVISYFRTLIDVNIFHEEVLTYIKEKSFNSLQDIHSVLPFENSKITNQIEDIQDSILNGYILIQYDTDKLNCLLVNVSKKEKRDITKAEIEYNIVGPQIAFVEDLDVNLNLVRRKLPTPYLQMKELKVGSLSNTTVAIVFIEGIVNDQNLQEIIKRVSQIKTDHVLDSTYLMQLIADNPNSIFPQFLNTERPDRVAAVLAEGKIALFVDGSPYAITLPTTLIDFFSTTEDYTMPWIIASFFRLLRLFAFIFSVLTTPLYVSILTYHYELIPKELLETLIISRSKVPFPPLIEALFLEITIELLREAGARLPTKVGLTVGIVGGIVIGQASVEASLTSNVLIIIVALSALSSFTAPIYRIGNTIRVIRFPFIISAHLLGLLGIVLTSSLLLARLLRTESLRRPYLFPFYPTRPTDWKDSIIRMPISAMFRRPIFSRSKQRFRFNPEEVEKNKILSRNDFDD
What is the function of this protein?
Required for the germination response to inosine.  Has no role in L-alanine germination.
What are the official names of this protein?
Spore germination protein GerQA.
What is the protein family that this protein belongs to?
Belongs to the GerABKA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YAIO_ECOLI
Sequence: MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAYAELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTPVFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTHYDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQRIQPLTEQLNLGLTAGKVWYDTPTDDFNGLQLAARLTWKF
What are the official names of this protein?
Outer membrane protein YaiO.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RF2_SHIFL
Sequence: MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIX7_YEAST
Sequence: MVKVKSKKNSLTSSLDNKIVDLIYRLLEEKTLDRKRSLRQESQGEEGENNEGEEDEDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKDVIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNEMNKRITSTWSKSGSVSESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPTTATDSSEDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYEDFLKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFRSALRKIKPSVSDKDRLKYDRLNKKMGLTEEMKDAEEMKQ
What is the function of this protein?
Involved in ribosome biogenesis.  Seems to be required for restructuring nucleoplasmic 60S pre-ribosomal particles to make them competent for nuclear export.
What are the official names of this protein?
Ribosome biogenesis ATPase RIX7.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: GLPK2_STRAW
Sequence: MPDNAQKYVAAIDQGTTSSRCIIFDHGGAIVAVDQREHRQIFPKPGWVEHDATEIWSKVQAVVAGAIAKAGLRADQLSALGITNQRETTVLWDRATGKPVHNAIVWQDTRTSALCHELGGSDGQDRFREQTGLPLASYFSGPKAAWLLDNVPGLRARAERGEIAFGTIDSWLIWNLTGGTDGGRHVTDVTNAGRTMLMNLETLQWDRSILSAMNVPEAVLPEIRSSSEVYGTAVGQLSGVPVASALGDQQAAVFGQACYDVGTAKNTYGTGSFLLLNTGNRPVPSKNGLLTTMGYKIGGEAPVYCLEGSIAITGALVQWFRDQLGIIRTADEIETLAASVDDNGGAYIVPAFSGLFAPYWRSDARGVVTGLTRYVTKAHLARAVLEATSWQTREVVDAMYQDSGVRITTLKVDGGMTKNNLLMQHQADVLGVPVIRPRVSETTCLGAAYAAGLATGVWNDLDELKSHWQKDVEWTPSMEASERDREYHNWRKAVEKSFGWHEEDGVN
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerokinase 2, GK 2.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TVP38_SCLS1
Sequence: MPADYSSTARALALPISPLESPPSSPIQHAERPPWSRRISSGVRRAYNSASPYSSQPTTSFKDQILRKADKLQRKCITAWQNLSTLQKCLAIVAAILNIVLVALFLVYQHQIFASLAPFAERWRDLPGGWMILWAMTFVAAFPPLIGYSSTITIAGFVYGVPKGWAIVATSTVAGSTCSFLASRTILSTYVHRLVGKDKRFEALALTLKHDGIKILCMIRLCPLPYSLSNAAVATFPTVHPLNYALATALVTPKLFIHVFIGSRLGSLAGNEGMDTSTKMINYASIVIGGGLGATVGYIIYQRTMARAKELEIEELEAANGDVAPGRRVAAEYSDANNDDAALMNDDDISLWDNTDEPARYTDFVDEDEANVFASGDLDEEADIGGRGKMTRT
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein tvp38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TES_RABIT
Sequence: MDLDSKMKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGRLFEDTKYTTLIAKLKTDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPYEMGGPSPDKLYIPAGDRSTPAALGPMESKPAECKGTQYFCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCSELLVDMIYFWKNGKLFCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNDFSWHASTQCFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: KANK2_MOUSE
Sequence: MAQVLHVPAPFPGTPGQASPAAFPSKEPDPPYSVETPYGYRLDLDFLKYVDDIEKGHTLRRVAVQRRPRLGSLPRGPGSWWTSTESLCSDASGDSRHSAYSYCGRGFYPQYGALETRIGSNPRVERTLLDARRRLEDQAAAPSSGGLGSLTPSAAGSTSSLAGVGLLPPTPRSSGLSTPVAPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSVLQEEKRQLTVQLKSQKFLGHPSGTRSRSELCLDLPEAPDDPAALETRSVGTWVRERDLGIPDGEAALVAKVAVLETQLKKALQELRAAQTQQVDLQPQAWPPPDTQVRVDTVRVVEGPREVEVAASTAAGALAQRAQSLEPYGTGLKALTTSGGPENTLVFRSHEVVETMCPLPTATTGNVHTAKKISITERSCTGAPRMTEPSSVNPRPAAASVVQPENPVPAAQDTTDKKPTRPAAASQDSQAADGAGRASLATKRKEDPADPEVNQRNLQFVGVNGGYESPSEDSSTAENSEHESTENEGPEPPARVLSPAECPQLRPPGAAVATTSLEGPQLSQESQRVPAPEVASGPDPEEEIRMDLSPDLISACLALEKYLENPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVRQLLDSGVCHVDKLNRAGYSPIMLTALATLKTQDDIETILQLFRLGNVNAKASQAGQTALMLAVSHGRVDVVRALLACEADVNIQDEDGSTALMCACEHGHKEITGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDYESPASSSAEE
What is the function of this protein?
Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (By similarity).  Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (By similarity).  Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (By similarity).  Involved in the negative control of vitamin D receptor signaling pathway (By similarity).  Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:25961457).  May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457).  Through the Rho signaling pathway may also regulate cell proliferation (PubMed:16024821).
What are the official names of this protein?
KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: Y959_METJA
Sequence: MKIDAVKKLLMIPGPTMVPPEVLNAMALPVIGHRTKDYSNLLEDTIEKLKKVFITENDTFLITGSGTAAMDMAISNIIKRGDKVLNIVTGNFGERFANIVKAYKGEAIRLDVEWGDMAEPEAVKEILDKYDDIKAVTVVHNETSTGARNPIKEIGEVVKDYDALYIVDTVSSLGGDYVNVDKFHIDICVTGSQKCLAAPPGLAAITVSEKAWEVIKKNDDKVGFYLDLLAYKKYYEEKKQTPYTPSVNLTYALNVALDLVLEEGIENRVKRHERLAKATRAGLEAMGIELFAKERARSVTVTSAKYPEGIEDSKFRGILSNKYNIVVAGGQKHLAGKIFRIGHMGICGEKEVLATLACVELALKELGFEVKESGVEVAKEVLLKE
What are the official names of this protein?
Uncharacterized aminotransferase MJ0959.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL1_HYDCU
Sequence: MGMAKLTKKQKMFAEKVDSLKSYDALEGFSLVSELATAKFSESIDVAIKLGIDPRKSDQVVRGATVMPNGTGKDVRVAVFTGDANAAAAKEAGAEFVGMDDLAAEVKGGMMDFDVVIASPDAMRVVGMLGQVLGPRGLMPNPKTGTVTPDVVTAIKNAKSGQVRFRADKAGIVHASIGKVDFAPEKLKENLNALIEDLNKAKPAAAKGTYMKKVSISSTMGPGIVLDQSSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HIS4_METBU
Sequence: MSFEVIPAVDMKGGKCVQLVQGVPGSEMISLDDPVEVALDWVSQGARTLHLIDLDGAIEGNRTNAPIIKKIVEKCKPQGIYIQVGGGIRSFEDAATLLDIGIDKVILSTAALKDPELIKKLSDEFGSEHINVALDSKNGKISIEGWTKESEHTAVEMGSQFEEKGAGSILFTNIDSEGLLNGVNPKPTEELVNAVTIPVIASGGVTTLEDIVTLKNTGAAGVVVGSALYKKRFTLTEAINIISDKN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUC1_MOUSE
Sequence: MAPSVVLRSFSRLLAPARLPSCSSTRSKFYVREPVNAKPNWLAVGLSVGASVFMWIYLIQTHNEDVLEYKRRNGLE
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial, Complex I-KFYI, CI-KFYI, NADH-ubiquinone oxidoreductase KFYI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: RL20_SHEPC
Sequence: MPRVKRGVTARARHKKVLKLAKGYYGARSRTYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAAARQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVVFATLVEKAKEALN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: YL137_MIMIV
Sequence: MHKIPCFVLIYEQFDIIKKCLTFLTKYAHRLHIVIIENYSVNTNQQIKPYVMDLLEKGIICKYYLFEENIANNAVHIVLEEAIAKYLDPTVFPYVFVTDGDLTIEDTNWIDEHVNIMDKHKNVFICGCSLDNSNLPTKTMPNAVHWIKPGIDQGDYIKGITGTTFTLHRTNELIEAIKFFNSKGWRYLDSNLHKFCFDAKRMIWARTKKAKCYHLTWDLYLDLTHPYTIMKLKNVNTMWKRSQSSKFQLYENSSDLRLDIYQELNDTKETIIVRKLKVISSGFDLGLDQSGIEYNGIFYPASRGFTVYTITDETVSVSNFDTHINSCTVNLARHIRESYRSGCHYIISVVHDDGFKKLSKNQLKEVGGLLSLDKIFYLYIRFSYYFVYDNIHKSLIDEDVSKVSFLSKEFSDLKFSKLISNNQITPSSTISNSNSQDLNIPDSTIIPLLSNNNGPITKQYHIVCLKWMLMFYREYIESFGSLLNIDYILLDNFNNYNYINSPEHVYIFCQLTDDSLLTKPFQKMILNTEQLTIAKYMDRTRKYINHGIQIIDYSIENIKLCNNPSTIYLPYQYSDSEIQILKKLYDSTPKKYDLVFCGSISQRRRYILDSLKSHGVSILELVTGHWGHPRDVEMASCKMLINIHYAHDYNIYESMRCDRWAFATMPVVSEDSIHYGLLDVKKHGLITFCEYDQLILKTLEALKNFKKTNENIINTVKKEREHQLIKVFTELK
What are the official names of this protein?
Uncharacterized protein L137.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L137 family.
Protein: FABZ_ECO27
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_NEIMF
Sequence: MFRIVKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWVPYNRISVNLKKALIASEDAHFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELPESDTD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FTSZ_CAUVC
Sequence: MAISLSAPRTTELKPRIVVFGVGGAGGNAVNNMIEAGLEGVEFVVANTDAQQLQFAKTDRRIQLGVQITQGLGAGAHPEVGMSAAEESFPEIGEHLDGAHMVFITAGMGGGTGTGAAPIIAKCARERGILTVGVVTKPFHFEGRHRMRLADSGIQELQRYVDTLIVIPNQNLFRVANERTTFAEAFGMADQVLHSGVRSITDLMVLPGLINLDFADVRTVMTEMGKAMMGTGEGTGEDRALMAAQNAIANPLLDEVSLKGAKAVLVNVTGGMDMTLLEVDEAANAISDQVDPEANIIFGAAFDPSLEGVIRVSVVATGMDGASIAQIEPKPVSRNISAAPLIAETSRPAPQPEPARPTARYEAARPAERPVAFAPEPAPEPEIVMSAPQPEPEAELYYDEPTVAEEPRVSAAPARSVNRIVDPLVDDVAEEPLFPENNYYEERRPQKQGGFFSMFGGGRQRYEQQASAPQAQARSAQSARPQLQPIETPQADDAEDLEIPSFLRRLAN
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: PSMG4_MOUSE
Sequence: MEESRAAADADVSLHNFSARLWEQLVHFHVMRLTDSLFLWVGATPHLRNLAVAMCSRYDPIPVCTSLFGDTSDTTSTGLAQRLARKTSKQVFVSYNLSNTDSNFTLLVENRIKEEMETFPEKF
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome.
What are the official names of this protein?
Proteasome assembly chaperone 4, PAC-4, mPAC4.
What is the protein family that this protein belongs to?
Belongs to the PSMG4 family.
Protein: LPTE_SHIDS
Sequence: MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGSDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ERA_BRUSU
Sequence: MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRGIFIEGPAQIVLVDTPGIFRPKRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALLESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDRTFMISALNGSGCKDLAKYLAESVPNGPWYYPEDQISDIPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVRIEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPERYREMGLDFPT
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: LL3_LASLA
Sequence: VNWKKILGKIIKVVK
What is the function of this protein?
Antimicrobial peptide which assumes an amphiphilic alpha-helix conformation upon contact with membranes (PubMed:19591185).  Insertion into membranes involves Trp-3 (By similarity).  Penetrates into cells once membrane has been permeated (PubMed:22100226).  Active against Gram-negative bacteria E. coli (MIC=1. 4 uM), P. aeruginosa (MIC=18. 7 uM) and Gram-positive bacteria S. aureus (MIC=3. 9 uM) and B. subtilis (MIC=0. 7 uM) (PubMed:19591185).  Has cytotoxic but no hemolytic activity (PubMed:19591185, PubMed:22100226).  Binds DNA in vitro (By similarity). In the context of inflammation and cancer tests, a 3-residues C-terminally truncated lasioglossin-3 is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:36548715).  In addition, this truncated peptide prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  This truncated peptide does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:36548715).
What are the official names of this protein?
Lasioglossin-3, LL-III.
What is the protein family that this protein belongs to?
Belongs to the lasioglossin-like family.
What are the subcellular locations of this protein?
Secreted.