PharMolix/UniProtQA huggingface dataset:
Protein: RTAI1_ARTBC
Sequence: MASVTSVPKTGRSVNQDVPATTLTLQTRPTPAPNFDEGEHLIRVHATALCAGELYWHTYVTFTKEETVPGPDVAGTVVLAPPSSPFKPGDDVYCRIPYSRAGGARDHTIALTSELARKPKNLTWEEAATVPLSALTAWQALFDQSGLWEGPEDERVKGKRVAVTAASGAVGMWILQFARIAGFDAVIGTCGDGNEDFVKSMGATDAVNYKTTSLTAWAAEKQGRKADLVIDCFGGKSLADAWGCVKDGGVLISMVGYPEQEKPAGLEVKDVKSHFFIMEPRGDQLQKVTELVEQGKCSFLMDSVYPLEQFQEATDKVESRRVRGKVVLKVL
What are the official names of this protein?
Probable zinc-binding oxidoreductase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLME_MARN8
Sequence: MARSKSSNRWLEEHVNDPFVKQAQQDGYRSRASYKLLEINNKDRLIKPTDLVVDLGSAPGGWSQVAAKLVGHKGRVVASDILPMDPIAGVEFIQGDFTEQEVFDQIMAILDGARADVVISDMAPNISGVNAADQAASMYLVELALDMACQVLKPKGSFVAKVFHGEGYDEYVKTVRESFDKVVIRKPDSSRARSREVYLVAKGFRVA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_CLOBB
Sequence: MADTFLLKIVTPDKDIFNGNIKRIFLKNSVGRLEILANHANMVTSTISSIVEFTDADGKDRKLFISKGIASIFNNEMTIFSESAEFSDNIDLNRAEKAKERAEKRLLEGNKYDKERAELALLRSIERINLKKMN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KTHY_METBU
Sequence: MKGKLITLEGIDGSGKSTITRFLNSHPAFANAVFTKEPTTSWIGDAVYKAIQSDTDELAELMLFTADHADHISTLIRPAIEEGKIVISDRYSDSRYAYQGVTLKERMEEPMEWIQMIHRGWTIIPDLTLLFDIDPAVAVQRCGKRGEQTKFEKTDLLKGVRENYLKLAEKEPERFVVIDTDRDLKEIEKDVLQAITSIIES
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RENT1_NEUCR
Sequence: MANMEVSFTHLGNHLVSDSAAAIKAGGSDELSNIDPDENLLYGVYGGRGPRGNGRRRHDDDDNETEVLDDDDDESLASVPVDGMKSLKLDAPVEEKELPPHACAYCGIHSPSSVVKCLTCNKWFCSAKGSAFSSHIVNHLVRARHKEVQLHPESSLGDTVLECYNCGTKNVFILGFIPAKSDTVVVLLCRQPCGASTSTKDMSWDISRWQPLIEDRAFLNWLVTPPTDAEQLRARHLTPPMIAKLEEMWKEAPNATVADLEKTAGVDDDPHPVLLKYDDPYHYQNIFGPLVKMESDYDKKLKEAQSEDGLQVRWHLGLNSKHVASFILPKIESGDVKLAVGDEMRLKYKGELRPPWEGVGYVIKIPNNQSDEVEVELRKSANDKSVPTECTHNFSADYVWKATSYDRMQLAMKTFAVDEMSVSGYIFHKLLGHEVQVAPTKITMPKKFHVPGLPELNASQIAAIKQVLSNPLSLIQGPPGTGKTVTSATIIYHLAKMSNSQVLVCAPSNVAVDQLCERIHRTGLKVVRLTAKSREDVESSVSFLALHEQVRMNTTNKELDGLVKLKTETGELSSQDEKRFKQLTRQAEREILQNADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPECMIPLVLGCKQVVLVGDHKQLGPVIMNKKAAKAGLNQSLFERLVKLQFTPIRLKVQYRMHPCLSEFPSNMFYEGSLQNGVTAAERLRKDVDFPWPVPETPMMFWSNLGNEEISASGTSYLNRTEAANVEKIVTRFFKAGVKPADIGVITPYEGQRSYIVNTMQNTGTFKKESYREVEVASVDAFQGREKDFIVLSCVRSNENQGIGFLSDPRRLNVALTRAKYGLVIIGNPKVLCKHELWHHLLVHFKDKKCLVEGPLTNLQPSLLQFGRPRQAYRPQRSHTQHVASGPSNGRFAAPLTAGSVRDYETGSMVSYIPDDVSSIHSSALGGAALSSGYPAMFSNFHPEAWAGLPCAGPNGRPGAKGRGRATESIAGESVANSEFTDATSSVIGGKGIGQGGASLGAGLSEAIGSARPTSYSQSDRLKQYVESNGRMGVGNGYRRYDDDEKSVSTAFASQIGTGFD
What is the function of this protein?
RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs (By similarity).  Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA (By similarity).
What are the official names of this protein?
Regulator of nonsense transcripts 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with polysomes.
Protein: CYSH_SALHS
Sequence: MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_CENSY
Sequence: MSHPQSRPGGRDGRPRRRREPREEAPWVPKTALGKRVNAGEITSLEEIQEAGARIQESGIIKKLLPDLKTEVVDVGIIQKMTSNGQSTRFKAIVAAGNENGYLGIGQGKAKQMRIAIEKANNQALLNVGPIKLGCGSWECRCDQKHSVPFKVRGKGGSVVIEILPAPRGLGLVAGGKIRRLLELAGLKDAYTTAKGSTPTTNSTSKAVLECLRQTFSQG
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MURG_STAAM
Sequence: MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HPPA_CHLTE
Sequence: MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVAAIIVAYFGGLNHLAPDKVVFILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPFPTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPCFIGFAIGESLGASVLRIAGGIFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALISFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLITLVWLTSIVSIVLTYIASYMLIAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECAFVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLMGAAFGFSTLGLDVMMLAPSVFAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFENAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILWPPFLLGLLMGGAVIYWFTGASMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEICTRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALFGLYQAIFMANAGGAWDNAKKVVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTISVSLAVVFFLLSLVFVHRSFFSMRIAVDKD
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force.
What are the official names of this protein?
K(+)-insensitive pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YPHF_ECOLI
Sequence: MPTKMRTTRNLLLMATLLGSALFARAAEKEMTIGAIYLDTQGYYAGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSSRTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKIDQPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIISTPDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDISGKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YphDEF.
What are the official names of this protein?
ABC transporter periplasmic-binding protein YphF.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CDX1_RAT
Sequence: KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQQQQQQPMPPTQLPLPLDGTPTPSGHPGSLCPTNAGLLGTPSPVPVKEEFLP
What is the function of this protein?
Plays a role in transcriptional regulation.  Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells.  Binds to the PRKD1 promoter in colorectal cancer (CRC) cells.  Could play a role in the terminal differentiation of the intestine.  Binds preferentially to methylated DNA.
What are the official names of this protein?
Homeobox protein CDX-1, Caudal-type homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI_ECOLI
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_PARPJ
Sequence: MNAAVIDSKNSQDFVVADMSLADWGRKELNIAETEMPGLVQTREEYKAQQPLKGARIAGSLHMTIQTGVLIETLTALGADVRWASCNIFSTQDHAAAAIAKAGTPVFAFKGESLDEYWEFSHRIFEWPNGEFANMILDDGGDATLLLILGSKAEKDRSVISKPTNEEEVALYKSIASHLDADPTWYSTRLAHIQGVTEETTTGVHRLYQMEKEGRLPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTATGNYHVIGHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWDNIKPQVDHIIFPDGKRVILLAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELFTQGEKYENKVYVLPKHLDEKVARLHLARIGANLTVLSDDQAGYIGVDKNGPFKPNHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_VIBCM
Sequence: MNKQVEIFTDGSCLGNPGPGGYGIVMRYKQVEKTLARGYRLTTNNRMEMLAAVMALQALKEPCRVILTTDSQYVRQGITQWIHNWKLRGWKTADKKPVKNADLWQALDKETARHQVEWRWVKGHAGHRENEMCDELARQAAENPTEDDIGYQPEPQ
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_ALIFM
Sequence: MITIKKGLDLPIAGVPTQVINDGKSITKVALLGEEYVGMRPTMHVRVEDVVKKGQVLFADKKNPGVVFTAPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANELVSLDRETIKTQLVDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAADAEVIINQQEEAFVAGLDLLSVLTGDKVYVCKKGGSLPRSSQKNVEEHVFDGPHPAGLAGTHMHYLYPVDTNHVAWSIGYQDVIAFGQLFLTGEIYSERIVSLAGPAVNNPRLVRTITGASLVDLTDSEVMPGEVRVISGSVLNGTQAAGPHAYLGRYHQQVSVLREGREKELFGWAVPGKNKFSVTRSFLSHLFSGQLFNMTTTTNGSDRAMVPIGNYERVLPLDMEATMLLRDLCAGDVDSAQRLGALELDEEDLGLCTYVCPGKYEYGPMLREILDTIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: CNPD1_MOUSE
Sequence: MDLTGLLLDEEGAFSLTGFQDFMVLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSSSDLFLISMMVASKYLYDEGEEEEVFNDEWGAAGGVAVATLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSSSPSPGPPELTLVSKSLVQPCVPAPVSQCLTNVSSCLEGSVDLPSLWGSLLAPLTPPLRPPPDPPAPPTPLHKCPLCQKFQRLPPNCRACHTNQTVSIGPSRPLYHARGLAPPWLWSPVAPPFLQPQQCSLFSVMELAHLKSVISPG
What are the official names of this protein?
Protein CNPPD1.
What is the protein family that this protein belongs to?
Belongs to the CNPPD1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MAP4_MOUSE
Sequence: MADLSLVDALTEPPPEIEGEIKRDFMAALEAEPYDDIVGETVEKTEFIPLLDGDEKTGNSESKKKPCLDTSQVEGIPSSKPTLLANGDHGMEGNNTAGSPTDFLEERVDYPDYQSSQNWPEDASFCFQPQQVLDTDQAEPFNEHRDDGLADLLFVSSGPTNASAFTERDNPSEDSYGMLPCDSFASTAVVSQEWSVGAPNSPCSESCVSPEVTIETLQPATELSKAAEVESVKEQLPAKALETMAEQTTDVVHSPSTDTTPGPDTEAALAKDIEEITKPDVILANVTQPSTESDMFLAQDMELLTGTEAAHANNIILPTEPDESSTKDVAPPMEEEIVPGNDTTSPKETETTLPIKMDLAPPEDVLLTKETELAPAKGMVSLSEIEEALAKNDESSAEIPVAQETVVSETEVVLATEVVLPSDPITTLTKDVTLPLEAERPLVTDMTPSLETEMTLGKETAPPTETNLGMAKDMSPLPESEVTLGKDVVILPETKVAEFNNVTPLSEEEVTSVKDMSPSAETEAPLAKNADLHSGTELIVDNSMAPASDLALPLETKVATVPIKDKGTVQTEEKPREDSQLASMQHKGQSTVPPCTASPEPVKAAEQMSTLPIDAPSPLENLEQKETPGSQPSEPCSGVSRQEEAKAAVGVTGNDITTPPNKEPPPSPEKKAKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTSGGLNKKPMSLASGSVPAAPHKRPAAATATARPSTLPARDVKPKPITEAKVAEKRTSPSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADLSRSKTTSASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSKVGSTENIKHQPGGGRAKVEKKTEAATTAGKPEPNAVTKAAGSIASAQKPPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEALPCPGPPAGEEPVIPEAAPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI
What is the function of this protein?
Non-neuronal microtubule-associated protein.  Promotes microtubule assembly.
What are the official names of this protein?
Microtubule-associated protein 4, MAP-4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Recruitment to microtubule is inhibited by microtubules polyglutamylation.
Protein: TPMT_NITMU
Sequence: MKKEYWLERWRQEEIGFHQREINPYLSRYWPELQVAPGKRVFVPLCGKSRDMIWLREQNLSVLGVELSPLAVEAFFKENGYSPRHIIGEKFDQWDADGIHLLCGDFFDLKKDHLAQVDAVYDRASLVALPPETRHAYTDHLLCILPPAIRILLITFDYPQAEMSGPPFAVSTAEVEALYGKRTDIRLLAKFDVLTENPRFQQRGISRLQESIFLLMTRTA
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN860_HUMAN
Sequence: MLREEAAQKRKEKEPGMALPQGHLTFRDVAIEFSLEEWKCLDPTQRALYRAMMLENYRNLHSVDISSKCMMKKFSSTAQGNTEVDTGTLERHESHHIGDFCFQKIGKDIHDFEFQWQEDKRNSHEATMTQIKKLTGSTDRYDRRHPGNKPIKDQLGLSFHSHLPELHIFQTKGKVGNQVEKSINDASSVLTSQRISSRPKIHISNNYENNFFHSSLLTLKQEVHIREKSFQCNESGKAFNCSSLLRKHQIIYLGGKQYKCDVCGKVFNQKRYLACHHRCHTGEKPYKCNECGKVFNQQSNLASHHRLHTGEKPYKCEECDKVFSRKSNLERHRRIHTGEKPYKCKVCEKAFRRDSHLTQHTRIHTGEKPYKCNECGKAFSGQSTLIHHQAIHGIGKLYKCNDCHKVFSNATTIANHWRIHNEERSYKCNKCGKFFRRRSYLVVHWRTHTGEKPYKCNECGKTFHHNSALVIHKAIHTGEKPYKCNECGKTFRHNSALVIHKAIHTGEKPYKCNECGKVFNQQATLARHHRLHTGEKPYKCEECDTVFSRKSHHETHKRIHTGEKPYKCDDFDEAFSQASSYAKQRRIHMGEKHHKCDDCGKAFTSHSHRIRHQRIHTGQKSYKCHKRGKVFS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 860.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURC_HISS2
Sequence: MQAFRQRIRQTVPEMRRVKQIHFVGIGGAGMGGIAEVLLNEGYQVTGSDIAENAVTSRLISLGAKISFSHHAANIEGASVVVVSSAIKGDNIEVITAHEKRIPVIQRAQMLAEIMRFRHGIAIAGTHGKTTTTAMVAMIYAQAGLDPTFVNGGLVKSAGTNAYLGCSRYLIAEADESDASFLHLQPMVSVVTNIEPEHMETYHGDFEEMKQTYVNFLRNLPFYGLSVMCADDPVLMELSSQVGRQVVTYGFSDEADYRIEDYQQTGFQGHYTVVAPNGERIDVLLNVPGKHNALNATAALTVAKEEGIENEAILTALAEFQGAGRRFDQLGQFIRPNGKVMLVDDYGHHPTEVNVTIQAARQGWENKRIVMIFQPHRYSRTRDLFDDFVQVLSQVDVLIMLDVYAAGEQAIAGADSRSLCRSIRNLGKVDPILVSDHKQLAEIVDQVIQDGDLILAQGAGNVSKLSRELALAWGKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK3_PICSI
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLTQDPDSKVACETCTKTNMVMVFGEITTKADVDYEQIVRKTCREIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEIGAGYQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNGTCAWLRPDGKTQVTIEYRNDGGAMVPERVHTVLISTQHDETVTNDQIAADLKQHVIKPVIPEKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVAAGLARRCLVQVSYAIGVPEPLSVFVDSYGTGTIPDKVILELIKKNFDFRPGMITINLDLKRGGNGRFQKTAAYGHFGRDDPDFTWEIVKPLKQEKALPA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 3, AdoMet synthase 3, Methionine adenosyltransferase 3, MAT 3.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_HELPH
Sequence: MDRAKFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVTSDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIENERKGEYLGKTIQIVPHVTDEIKRRIKSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTTNELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKNKIALSCDVEQDSVIVATDTKSIYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVKIGFVGKYLSLKESYKSLIEALIHAGAHLDAQVNIEWLDSENFNEKTDLEGVDAILVPGGFGERGIEGKICAIQRARLEKLPFLGICLGMQLAIVEFCRNVLGLKGANSTEFNQRCEYPVVYLIGDFMDQNHQKQVRTYNSPLGGTMRLGEYECEIMPNSLLEKAYKKPSIKERHRHRYEINPKYRQEWESKGLKVVGFGANHLIEAIELEDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSALSKS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CCKA_BRUA2
Sequence: MRPKWCKTTVLASFPRGSACTARQLKHSANRIYLDARASVPARRAGILNEDRIELPDDAIGASAERRSTRDLRKPSRAGIQHERAVGLMSRQTDNTYPKPLVMPKRGPSAALRLLIVGILLMGAAFIYFLFRDQLGDGFALVLMGVLSMVGVFYLFGAATGLIQFSQRSDHQDLAHSFMDTQPEGTVISDPRGQIVYANQAYARMTGATDADGIRPLDQVLASEPAASDAIYRLTNAVRDGLSAQEEVRISGGLSRGANGSLAPVWYRIKARALEGGAEFKGPLVAWQVADISEERAEQERFFQELQEAINHLDHAPAGFFSANPAGRIIYLNATLAEWLGVDLTQFTPGSLTLNDIVAGSGMALIKAVKAEPGTSRNTVIDLDLIKRNGQSLAVRFYHRVQTARDGMPGTTRTIVLDRAEGDDSSVAQRSAEVRFTRFFNSAPMAIAAVDAEGHTLRTNARFLDIFSGVVDRDAIDRRVKLENVVHERDRETFNKALAAAFAGQASISPVDTVLPGNEERHIRFYMSPVTDLGGEAAEEAAVISAVETTEQKALENQMAQSQKMQAVGQLAGGIAHDFNNVLTAIIMSSDLLLTNHRASDPSFPDIMNIKQNANRAASLVRQLLAFSRRQTLRPEVLDLTDVLADLRMLLARLVGKDIELKIDHGRDLWPVKADLGQFEQVAVNLAVNARDAMPEGGQITLRTRNIPAADAAKLHYRDLPEADYVVFEVEDTGTGIPADVLEKIFEPFFTTKEVGKGTGLGLSMVYGIIKQTGGFIYCDSEVGKGTTFKIFLPRLIEEKRADDAPVAAKEKKVEKATDLSGSATVLLVEDEDAVRMGGVRALQSRGYTVHEAASGVEALEIMEELGGEVDIVVSDVVMPEMDGPTLLRELRKTHPDIKFIFVSGYAEDAFARNLPADAKFGFLPKPFSLKQLATTVKEMLEKQD
What is the function of this protein?
Component of a regulatory phosphorelay system that controls B. abortus cell growth, division, and intracellular survival inside mammalian host cells.  This signaling pathway is composed of CckA, ChpT, CtrA and CpdR.  CckA autophosphorylates in the presence of ATP on a conserved His residue and transfers a phosphoryl group to a conserved Asp residue on its C-terminal receiver domain.  CckA-P transfers phosphoryl groups to the ChpT phosphotransferase.
What are the official names of this protein?
Sensor kinase CckA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: F86C2_HUMAN
Sequence: MAPEENAGTELLLQSLERRFLAARALRSFPWQSLEAKLRDSSDSELLRDILQKHEAVHTEPLDELYEVLAETLMAKESTQGHRSYLLTCCIAQKPSCRWSGSCGGWLPAGSTSGLLKSMWPLPSATQRRASCSPLSYAGLGSDGKWNLVMTRNCFPTKSTWRWQC
What are the official names of this protein?
Putative protein FAM86C2P.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.
Protein: TSAD_PROM5
Sequence: MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIPFVLEEALEESKISIEEIDAIASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGRSYDDAAGEAFDKVGRLLGLSYPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDEIPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIKVHLAPLNLCTDNAAMIGAAALFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC2_STAAB
Sequence: MKEKIVIALGGNAIQTKEATAEAQQTAIRRAMQNLKPLFDSPARIVISHGNGPQIGSLLIQQAKSNSDTTPAMPLDTCGAMSQGMIGYWLETEINRILTEMNSDRTVGTIVTRVEVDKNDPRFDNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYRKVVASPLPQSILEHQLIRTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASEKLATLIEADTLMILTNVENVFINFNEPNQQQIDDIDVATLKKYVAQGKFAEGSMLPKIEAAIRFVESGENKKVIITNLEQAYEALIGNKGTHIHM
What are the official names of this protein?
Carbamate kinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.