PharMolix/UniProtQA huggingface dataset:
Protein: TBP_MESAU
Sequence: MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQREQQQQQQQQQQQQQQAVATAAASVQQSTSQQSTQGASGQTPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.  Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III.  Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription.  The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter.  SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_TOLAT
Sequence: MRIILLGAPGAGKGTQAQFLMEKYGIPQISTGDMLRAAIKAGTALGLQAKAVMDAGQLVSDELIINLVKERVTLEDCKNGFLLDGFPRTIPQADAMKEAGINVDFVLEFDVPDEEIVKRMSGRRVHAGSGRVYHVVFNPPKEEGKDDVTGEALSIRADDEETTVRKRLDIYHQQTEPLVGYYKKEAELGNTRYSKIDGTQQVAEISKQLAVLLG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y9099_DICDI
Sequence: MNNNNKKGVYILWVHDQQFSKEELVVNPEYFPKLKIMDVLKIYSPSNPSKRLCLRVKQLSPLKTKLQISISKYVAGVFDFALRKEVVVNIIPEKQAIIDFVELSFKDQYIGRSDMWRLKLNLQNECVYVLKKLAFAQIRAQVEEMVSNGQKVSSGLIDDSTKFVFRSRSAKFVLFIQMSKEMWDYSPDGELYFEKAVNGFLKNLFQRWKSLSVNHTITIILFSRTFHENDDILDEIPNIPRNPQGKLYQDFYKVVVNEETRPDWSSIIVNLKREFNDYHTSVNWDIYGRNSALGKNSTASQGNFLEAINLGMSYFDKHYIDRDFTRTGQMIVVISAGTGIFEVDPDINLITKQRMIDNGIGCDLICLNNHPLHVVPLFKFTISNQNKSQNTIQNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNKNNQNNGKAISNIGRNNNNSNSGSSGNSNNSSGGQLYNFPYWLAISFYDENNTTTTTTDVTTNDKRNGLFVPQFKIPEKVNSFYYEDDEKPVYDFYIPKDPRNLPAFATPKINHKYTSNSLGVNSYEDTIFNMPNGGGILDDSNALGGNNNNNYNNNNGNGNGHNHNNHNNNNNNNNNNDHGGHSDTEPSDFSDTEDNSSTTPNSQYSRVAIGLNDKKRATFQIGGTRSSSSFENQRTIINSTTSNNNNNNSNNVVNKRYTSTQHQPILRNGGTINNNNNNQQNHPISPSNSFDQKTIPYHNQLLSTIPPQLFGKKKKEINPFTYDSTPFHLTSNRRRWSHLWFSPNTYIFGKTNTNPNPFLPNWKSLCEPASLPITTDYFPSTKDLKAKYREYVHNLTLPDDNEYTNSFEALLKELISQRLAQGYQLIMITNSEIDPTTTTTTGGTTTPATTTPATTTPATTATSTTPTTIITPTTNPSTATSAIATPSMATPSSSTTTTTTTANLSTSPPNSSNTVPNSGGSGKGTKKSYQLSLGHDFHSITYDPSNLSIQVKRYQRYNGRNSSGSKKLRYHYFLNTIHLQGFLHNSIELQHTASSEYPWNSLDNLICGQLAMSGFGPRIKYWRVLYAIIPTVENNQHQQQLQLEQQEKEKEKARLAALEKKKPFPREDSFSTLILPTNSSSSSSSSSSLPSTVSTTNTNTNNNNNNNNNNNNNNINTTVPTNVPTTTTTDDSTVKNTSTTTATTATEDHGLNTAFNSSSIPIPSKLASPLQSPNLSPKASSVSTSMAALSSSTLVSSNANTTTTNNPVLTTTTTTTTTTAVLNSNGTPLVNSNSSSNSNFAQNSISMLNGSQQQQQLIGSQSAPTSPLTPHKNINTNNNNNNNTTTNTTNNNNSVMNGSAGIINSSSGLNGIKSPPLPILPSSNSLLSSNVSPSNNITPLNSITNSSELLPSSSGASSSSSNTLSSSNSGENNALPEHTEEERLIAFNKFKEFINSQINRNQLAANSNAQSSLLNSSTNNANSNNSSNSTNTSGTVIQQKLDIKTILFSSIETFDPSTIVSNEKSNNNTYTNNNNNNNSINSLNYNSVPSQEQIDLFKEKLYSSNLSGIFYRLNMPYPIGIKMTERKYGIRRTSYKKCFIGAECIDWMLQNIEITKREEALIICQKMMDQKLIKQVEKSTFVDGQFYYRLKEDDLFISSPIIKTINNTNNNFNNNNTNSNNNQQQQQQQQSIPSVTSSAVNSPNKDSNTPDHSPISSPKQIGNKLSSSSNNTPSTFLNSSTNNTNQSTNTTSSSSSTTNINTTLNTNNTLSSSTPPITSIQSSMSNSTKSVVPISSLSSLINNPSLRQSNTDYLTNKEKDKEKEIDEANGDNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNGENDSSSNSGQGSLNSTLSSIPPATTPNTNPLHFSGGISYGSSVQNSNQHQQQQPQQPQQQQQQQQQQQQQPNNLIDYYENPNKISEAKIEMDLSKTDRFEWILMKYDKTFCPTRYFHVEFNWIVSTGCVVDDFINSCVRKAKQFGLTLIQIPMEKNYSPFSLPTHVHLDQQLMSPQVLKHIFTKFGLIPDTIRKRASSLVTRQDLYIFNDSDVQYSEYVHRTGLLFVRVVEDGFLCYINNAPSNRPFLPAATMCLESFQNLCNQLNNSLSFIGNGSLNSNNNYNNNNNNNNNNNGGGNGNPNLLKPIDRQEANFLSLLALGYKQNSDTEEKNNESDSDNNHNQDTCDNSDNDTDHLSESHEGSHKNESDKEGRDKNEMWESQSEVVYYSVMSRSPLLGSFNE
What are the official names of this protein?
DEP domain-containing protein DDB_G0279099.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the IML1 family.
Protein: RL19_STREM
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFEGVVISRKGQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: YJDP_SHIDS
Sequence: MKPYSTLFLFTLLTLTTVPAQADIIDDTIGNIQQAINDAYNPDHGRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQHQLDQERRQLEDEERRMEDEYGQ
What are the official names of this protein?
Uncharacterized protein YjdP.
Protein: LLDD_VIBPA
Sequence: MIISASTDYRAAAKAKLPPFLFHYIDGGSYDERTLKRNTDDLGDVALRQRVLRDMTDLSLETEIFGEKLAMPIALAPVGLTGMYARRGEVQAAKAAEKKGIPFTMSTVSVCPIEEVAPAIERPMWFQLYVLKDRGFMKNVLERAKAAGVTTLVFTVDMPVPGARYRDMHSGMSGPNAAMRRVFQAMRHPSWALDVGLLGKPHDLGNISTYRGEPTKLEDYIGWLGANFDPSISWKDLEWIRDFWDGPMVIKGILDEEDAKDAVRFGADGIVVSNHGGRQLDGVLSTAKALPSIADAVKGDLKIFVDSGIRTGLDVVRMLALGADCTLLGRSFVYALAAQGGAGVENLLDLYDKEMRVAMTLTGAKTIADLSRDSLVKIP
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CHI2_ARTBC
Sequence: MKTPFTILAALTVATTLADVPDEWDIIELSFGEPTSVDSGEIKFAMCPKTECPNVESEEEFKAAIKAKRAKGKKVLLSIGGQNGQVQLKTTEARDKFVSSVGGIIDKYGLDGLDIDFEGHSLYLDQGDTDFKNPKTSVVVNLIAALKSLKEKYGKAFVLTMAPETFFVQLGYSSYGPSNGNDARAGSYLPVIHAMRDDLTVLQVQNYNSGPIIGLDDQYHNVGTPDFLIAMADMLKAGFPVAKTNNTFPPLREDQIAIGLPSTVSAGNGFVDEKGVQDALNCLMKGESCGTYKPRGGKSPSFRGLMAWSINWDKFSNWGFLNPHRKYLDSFP
What is the function of this protein?
Degrades chitin and chitotriose.
What are the official names of this protein?
Probable class II chitinase ARB_00204.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPE_MYCS2
Sequence: MAVPASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVAGGMAGGSADAAGVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVVPAPSAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SYW_LISMF
Sequence: MKKVIFSGIQPSGQLTLGNYIGALKQFGQFQDEYECFYCIVDEHAITVPQDRLKLREQTRSLAALYLAVGLDPEKATLFIQSEVAAHAQAAWILQCNVYIGELERMTQFKDKSDGKAGVSAGLLTYPPLMAADILLYQTDLVPVGEDQKQHIELTRDLAERFNKKHADIFTMPEVFIPKQGARVMSLQDPTKKMSKSDANLKNAIFLLDPPATIRKKIKSAVTDSSGIIEYNKEEKPGVSNLLTIYSVITGETISTIEEKYVGKGYGDFKTDLAELVVAELEPIQERYYAYLKSEELDTILDAGAEKAARVANKTLKKMENGVGLGRKRRR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP2_CROAT
Sequence: MVLIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVAIFNSTEFFCSGTLINQEWVVTAAHCDSTNFKMKLGVHSKKVPNEDEQTRNPKEKFFCPNKKKDDVLDKDIMLIKLDSPVSNSEHIAPLSLPSSPPSVGSVCHIMGWGSITPIEKTLPDVPYCANIKLLDDAVCQPPYPELPATSRTLCAGIPEGGKDTCGGDSGGPLICNGQFQGIVFYGAHPCGQALKPGVYTKVFDYNDWIQSIIAGNTAATCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease catroxase-2, SVSP, Catroxase II, Kallikrein-like EI.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCPP_YERPS
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVIEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: YKT6_ASHGO
Sequence: MKIYSIAILRNSGNKALELCSAKDLSQFGFFERNGVSQFMTFFGETVAGRTGAGQRQSIEEGNYVGHVYSRSEGLCGVLITDKEYPVRPAYTLLNKVLDEYLVAHPPAEWRDIAQTSDQLKLRELEMYLAKYQDPSQADSIMRVQQELDETKIVLHKTIESVLQRGEKLDNLVDKSESLSASSRMFYKQAKKTNSCCLIM
What are the official names of this protein?
Synaptobrevin homolog YKT6.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PRP46_YARLI
Sequence: MPVAKDLFPEYGTLATGENEPSRNIRRAQKLREFQNLELPPYLAKQVAAKMAEKGLAVEATGGVAVQRIAGGSQSGQKALMGASSSALTKHTPSASQPTTHDSLTNLGANLTQSKPAWHAPWEIYRVITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTHHKKSVRGLTLHPEEFTFSTASANSSKQWKCPEGDLVLNYDDQNAIINTLSVNQDNVMFSGGDNGSIGFYDWKTGHMFQSTQSIPIPGSIESENGIFDSSFDKTGLRLITCEADKSIKMWREKPNATAESDPGLEWKPKIYQTY
What is the function of this protein?
Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
What are the official names of this protein?
Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 46.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1450_THEGJ
Sequence: MYRIKDEWGEFLVRLARKAIEEYVRNGRVIEPPEDTPPELWEKMGVFVTLNRYRAPPQMALRGCIGFPLPIYPLVEATIKAAIHAAVEDPRFPPVRPEELDELTVEVSVLTPPEPIEGPPEERPRKIKVGRDGLIVEKGFYSGLLLPQVPVEWGWDEEEFLAQTCWKAGLPPDCWLDPDTKVYRFTAEIFEEEYPRGPVRRKPLV
What are the official names of this protein?
Protein TGAM_1450.
Protein: LSPA_NOSP7
Sequence: MRLKNRLFWIAAFIAFFLDQITKYWVVQTFSLGQTLPLLTGIFHFTYVTNTGAAFSLLSGKVEWLRWLSLGVSLVLIALALFGPTLNLWDQLGYGLILGGAMGNGIDRFVLGHVVDFLDFRLISFPVFNVADSFISIGIVFLLIASFQKTPTSTGRLD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: L_EBORE
Sequence: MATQHTQYPDARLSSPIVLDQCDLVTRACGLYSSYSLNPQLRQCKLPKHIYRLKFDTIVSKFLSDTPVATLPIDYLVPILLRSLTGHGDRPLTPTCNQFLDGIINYTLHDAAFLDYYLKATGAQDHLTNITTREKLKNEILNNDYVHQLFFWHDLSILARRGRLNRGNNRSTWFVHDEFIDILGYGDYIFWKIPLSLLPVTIDGVPHAATDWYQPTLFKESILGHSQILSVSTAEILIMCKDIITCRFNTSLIASIAKLEDVDVSDYPDPSDILKIYNAGDYVISILGSEGYKIIKYLEPLCLAKIQLCSKFTERKGRFLTQMHLSVINDLRELISNRRLKDYQQEKIRDFHKILLQLQLSPQQFCELFSVQKHWGHPILHSEKAIQKVKRHATILKALRPNVIFETYCVFKYNIAKHYFDSQGTWYSVISDRNLTPGLNSFIKRNHFPSLPMIKDLLWEFYHLNHPPLFSTKVISDLSIFIKDRATAVEQTCWDAVFEPNVLGYNPPNKFSTKRVPEQFLEQEDFSIESVLNYAQELHYLLPQNRNFSFSLKEKELNIGRTFGKLPYLTRNVQTLCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGENATVRGSSFVTDLEKYNLAFRYEFTAPFIEYCNHCYGVRNVFNWMHYLIPQCYMHVSDYYNPPHNVNLSNREYPPEGPSSYRGHLGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVMGDNQCITVLSVFPLETDPEEQEQSAEDNAARVAASLAKVTSACGIFLKPEETFVHSGFIYFGKKQYLNGVQLPQSLKTAARMAPLSDAIFDDLQGTLASIGTAFERAISETRHILPCRIVAAFHTYFAVRILQYHHLGFNKGIDLGQLSLSKPLDYGTITLTLAVPQVLGGLSFLNPEKCFYRNFGDPVTSGLFQLRVYLEMVNMKDLFYPLISKNPGNCSAIDFVLNPSGLNVPGSQDLTSFLRQIVRRSITLTARNKLINTLFHASADLEDEMVCKWLLSSNPVMSRFAADIFSRTPSGKRLQILGYLEGTRTLLASKIINNNSETPVLDKLRKITLQRWNLWFSYLDHCDQLLADALQKISCTVDLAQILREYTWSHILEGRPLIGATLPCMVEQFKVKWLRQYEPCPECLNKKGSNAYVSVAVKDQVVSAWPNTSRISWTIGSGVPYIGSRTEDKIGQPAIKPRCPSSALKEAIELASRLTWVTQGSSNSEQLIRPFLEARVNLSVSEVLQMTPSHYSGNIVHRYNDQYSPHSFMANRMSNTATRLIVSTNTLGEFSGGGQAARDSNIIFQNVINLAVALYDIRFRNTNTSDIRHNRAHLHLTECCTKEVPAQYLTYTSALNLDLSRYRDNELIYDSNPLRGGLNCNLTMDSPLVKGPRLNMIEDDLLRFPHLSGWELAKTVVQSIISDNSNSSTDPISSGETRSFTTHFLTYPQIGLLYSFGAVLCFYLGNTILWTKKLDYEQFLYYLHNQLHNLPHRALRVFKPTFKHASVMSRLMEIDSNFSIYIGGTSGDRGLSDAARLFLRTAIASFLQFLKSWIIDRQKAIPLWIVYPLEGQQPESINEFLHKIFGLLKQGPKNIPKEVSIQNDGHLDLAENNYVYNSKSTASNFFHASLAYWRSRKSRKTQDHNDFSRGDGTLTEPVCKFSSNHQSDEKYYNVTCGKSPKPQERKDFSQYRLSNNGQTMSNHRKKGKFHKWNPCKVLMESQRGTVLKEGDYFQNNTPPTDDVSSPHRLILPFFKLGNHNHAHDQDAQELINQNIKQYLHQLRSMLDTTIYCRFTGIVSSMHYKLDEVLLEYNSFDSAITLAEGEGSGALLLLQKYSTRLLFLNTLATEHSIESEVVSGFSTPRMLLPIMQKVHEGQVTVILNNSASQITDITSSMWLSNQKYNLPCQVEIITMDAETTENLNRSQLYRAVYNLILDHIDPQYLKVVVLKVFLSDIEGILWINDYLAPLFGAGYLIKPITSSARSSEWYLCLSNLISTNRRSAHQTHKACLGVIRDALQAQVQRGVYWLSHIAQYATKNLHCEYICLGFPPLEKVLYHRYNLVDTGLGPLSSVIRHLTNLQAEIRDLVLDYTLMRESRTQTYHFIKTAKGRITKLVNDFLKFSLIVQALKNNSSWYTELKKLPEVINVCNRFYHTHSCECQEKFFVQTLYLQRLRDAEIKLIERLTGLMRFYPEGLIYSNHT
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: VXIS_BPL54
Sequence: MCVKFTDAEIAYIKESVENYSSEFDIYDDEQELKLKIYEQIMLKIKSEYKDTYLFRLIN
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.
What are the official names of this protein?
Excisionase.
Protein: RNY_STAEQ
Sequence: MNLLSLLLILLGIILGVVVGYIVARNLLHQKQVQARQTADDIVSYANKEADNIKKEKLLEAKEENQILKEQAENELRERRGELQRQETRLLQKEENLDRKSDLLDKKDEILEQKESKLEERQQQVDAKESSVQTLIMKHEQELERISGLTQEEAVKEQLQRVEEELSQDIAILVKEKEKEAKEKVDKTAKELLATTVQRLAAEHTTESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIRDAGEQATFEINVHNMHPDLVKILGRLNYRTSYGQNVLKHSIEVAHLSGMLAAELGEDVTLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYNENNIIINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVVVSPEEIDDLKSYRLARDIKNQIEEELQYPGHIKVTVVRETRAIEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NAPA_AGGAC
Sequence: MNLSRRDFMKANAAMAAATAAGLSIPVKNVEAAESEIKWDKAVCRFCGTGCAVLVGTKDGRVVASQGDPDAEVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGKYDKNGDFTPVSWDVAFKTMAEKFKAAVKELGPNGVGMFSSGQTTIFEGYAKSKLWKAGFRSNNIDPNARHCMASAAVAFMRTFGMDEPMGCYNDIEQAEAFVLWGSNMAEMHPILWSRITDRRLSNQDVKVAVLSTFEHRSFELADYSLIFKPHTDLVILNYIINYLIQNDAINRDFVNKHTKFKRGETDIGYGLRPENPLEQKAKNVKTAGKMYDSNFDELKALVAEYTLDKAHEMSGVPKDVLENLAKLYADPKKKVVSYWTMGFNQHTRGVWANHLIYNIHLLTGKISIPGCGPFSLTGQPSACGTAREVGTFIHRLPADLVVTNPKHREKAEQIWKLPAGVITDVLGFHAVAQSRALKDGKMRVLWQMCTNNMQGGPNINRETFPGWRNPDNFIVVSDPYPTVSCLAADLMLPTAMWVEKEGAYGNAERRTQFWRQQVKAPGEAKSDVWQLVEFSKYFTTDEMWPAEILDKNPEYKGKTLYDVLYRNGQVDKFPLSELAEGQLNDESYHFGFYLQKGLFEEYASFGRGHGHDLASFDTYHKARGLRWPVVDGKETLWRYREGYDPYVKEGEGVAFYGYPDKKAIILAVPYEPPAESPDEEYDLWLCTGRVLEHWHTGTMTRRVPELHRSFPNNLVWMHPTDAQKRGLRHGDKVKVASRRGEIISFLDTRGRNKVPEGLIYTTFFDAGQLANKLTLDATDPISKETDFKKCAVKVEKAA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: YJIJ_ECOLI
Sequence: MPSSTHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAEGSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWLPPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLAGLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAILYGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPCLTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLSNGTSALASATLCGAAALFIAALISTVQLFKLQVVTS
What are the official names of this protein?
Uncharacterized protein YjiJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASSY_DEHMC
Sequence: MSEKVVLAYSGGLDTSAAVKWLQEKYGMDVIAVTIDVGNEKDFTLIKEKALKVGAKKAYVRDVRKEFAEDYIWKAIKANSMYEGVYPLATALARPLIAKVMVDIALEEGATAIAHGCTGKGNDQVRFDVGINTLAPHLKIIAPARQWGMTREQTMEYAQKWGIPVPISVKNPFSIDENLWGRSIECGLLEDPWNEPIPEVFAWTRPVEETPDEPEYLEVEFEQGVPVAVNGEKLSPLALIQKVHDIASLHGVGRIDHVENRLVGIKSREIYEAPAAVVLIAAHQALEAMTLSKSQLRFKQMVEATYSDIIYNGLWFSALRQDLDAFIDSSQRFVSGTVRLKLSKGSFRVVGRKSPYSLYHKGMATYDKGDQFDPSSAVGFITLWGLQAKLQAQLQPILEEEKGNKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_GEOSM
Sequence: MIDFLGGWKRTSYCGELRGGHIGQEVTLMGWVSKRRDHGGLIFVDLRDRDGISQIVFDPERCAEAHAKAESVRNEYVLAIKGTVAARPEGTVNPKMKTGEIEVLVTECKLLNPSKALPFTLDGFVDVNENIRLKYRYLDLRTGTLQQNLILRSKVAQLTRSYLSDNGFIELETPFLTKSTPEGARDFLVPSRINKGEFYALPQSPQLFKQILMVSGFDRYFQIVRCFRDEDLRADRQPEFTQIDCEMSFIDREDIITVMEGLMARIFTEAKGVKVELPIERMTYQEAIRRFGVDNPDLRFGLELVELSDIVKNSGFKVFADVVNGGGIVKGMNVKGAGAMSRKEIDDLTEFAKIYGAKGLAYVKMTAEGWQSPIAKFFTPEEIATMDKAFDAKEGDLLLFVADKPKVVNDSLGKLRNHLAAKMGLTDPNVFRFVWITDFPLLEWDEEAKRWAAVHHPFTAPMDEDLQYVESDPGRCRAKAYDLVLNGNEIGGGSIRIHQEEVQSLMFKMLGLSEENARSKFGFLLDALEYGTPPHGGIAFGLDRLMMLITGSDSIRDVIAFPKTQKGACLMSDAPSGVDALQLRELGIRLAAK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPD1_RAT
Sequence: MPLFKLTGQGKQIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLREMQAHIFHMENLSMSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVAIESFYPVFTPPPKKGEDPFRREDLPANLGYHLKMKGGVIYIYPDEAAASRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYHIDADRVVYSTKEKNLTLKELFAQLNMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVDAKYQHAEPRLSIYGRSPDEWSKLSSWFVGNRIYCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFLPVFEATINPQTHPDLSVFLKHITGFDSVDDESKHSGHMFSSKSPKPEEWTMENNPSYTYYAYYMYANIMVLNCLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADNISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKAKFLGNNYLEEGPVGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKSTE
What is the function of this protein?
AMP deaminase plays a critical role in energy metabolism.
What are the official names of this protein?
AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: APT_MYCFP
Sequence: MDLKKYIRDIENFPKTGIMFKDISPLLANGKALNYTITEMAKLAQDVDVIVGPDARGFLFGTPTAAFLKKPFIMVRKPGKLPGDVISKSYDLEYGNNVLQIQKGFIKKGQTVAIIDDVLATGGTTKAIIKLLEEQGAIVKKVILLLELVDLNGRQLITKDNDIEIVSLVKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_ECOLC
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPPP_RHOBA
Sequence: MQELIRVVILAIVQGIAEFLPISSSGHLVILGSMLGELGESVTLEIILHAGTLGSILVVFWQRIWALLLKDRRVIGLLVIGTLPAVVIGLTIKTQFPEILRSPLLAGAMLIVTGVMLIVLGRLTPKSGTYDRLGLGAAFLVGCFQAFAILPGISRSGSTILGGRLMGLDRDDSVTFSFLLAIPAILGATVLAIKDLLEDGSSGETSIEVLSIGAAVAFAVGIVALKWLIRWSREDRLHWFAYWCIPAGLLVVLLNLR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL31_THEGJ
Sequence: MPIEPGQEVIFVVPIRKIKKRVPRWKRAPRAAKFVREWIARHAKAEEVKLEPAVNEKLWERGAEKPPNKLRVKVVVEVVDGKRVAKVSLA
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.