PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_GEOTH
Sequence: MTRGRVIQVMGPVVDVKFENGHLPAIYNALKIQHKARNENEVDIDLTLEVALHLGDDTVRTIAMASTDGLIRGMEVIDTGAPISVPVGEVTLGRVFNVLGEPIDLEGDIPADARRDPIHRPAPKFEELATEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTAKGSITSIQAIYVPADDYTDPAPATTFSHLDATTNLERKLAEMGIYPAVDPLASTSRALAPEIVGEEHYQVARKVQQTLQRYKELQDIIAILGMDELSDEDKLVVHRARRIQFFLSQNFHVAEQFTGQPGSYVPVKETVRGFKEILEGKYDHLPEDRFRLVGRIEDVVEKAKAMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCL4_BOVIN
Sequence: MKLCVTVLSLLVLMAAFCSPALSAPMGSDPPTACCFSYTLRKIPRNFVNDYFETSSLCSQPAVVFQTKKGRQVCANPSEPWVQEYVDDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RTX1B_ACTPL
Sequence: MDFYREEDYGLYALTILAQYHNIAVNPEELKHKFDLEGKGLDLTAWLLAAKSLELKAKQVKKAIDRLAFIALPALVWREDGKHFILTKIDNEAKKYLIFDLETHNPRILEQAEFESLYQGKLILVASRASIVGKLAKFDFTWFIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVVLFEIVLNGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDLMFSFIFFAVMWYYSPKLTLVILGSLPFYMGWSIFISPILRRRLDEKFARGADNQSFLVESVTAINTIKALAVTPQMTNTWDKQLASYVSAGFRVTTLATIGQQGVQFIQKVVMVITLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISVTRLGDVLNSPTESYQGKLALPEIKGDITFRNIRFRYKPDAPVILNDVNLSIQQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIRDNIALADPGMPMEKIVHAAKLAGAHEFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRNMHQICKGRTVIIIAHRLSTVKNADRIIVMEKGQIVEQGKHKELLADPNGLYHYLHQLQSE
What is the function of this protein?
Involved in the transport of the toxin RTX-I as well as that of RTX-II.
What are the official names of this protein?
Toxin RTX-I translocation ATP-binding protein, APX-IB, Cytolysin IB, CLY-IB, HLY-IB, RTX-I toxin determinant B.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPA_VIBVU
Sequence: MSKPIQMEKGVKYRDADKMALIPVKNMPTEQKEVLRKPDWMKIKLPADSQRIQDIKSAMRKNNLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLPPEAEEPTKLAKTIADMKLKYVVITSVDRDDLRDGGAKHFADCNREIRAQSPHIRIETLVPDFRGRMDVALEALKDNPPDVFNHNLETAPRLYRKVRPGANYQWSLDLLKKFKEQHPDVPTKSGLMMGLGETKEEIVEVLKDLRAHGVTMLTLGQYLAPSRHHLPVERYVPPAEFDELKEIALELGFTHAACGPFVRSSYHADMQAQGLEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB21_ARATH
Sequence: MNSEENTDSIPIDLILDILSRLPSKSIARCRCVSKLWESMIRQSYFTELFLTRSSSRPHLLIAVEQEGEWKFFSLPQPKNYLGKSSLVVAANLHLKFFEDKRPQHGCSYASSLIYFPNMTIRKKGDDHLGVICNPSTGQYGYVILPPLLDFKSVPYGKFLGFDPIDKQFKVLIPIFDFDKHQTDHHILTLGAETVGWRKIQSPLRYLPHSNGTICINGILYYLAKINYAMDKNVLVCFDVRSENFVFLRLNTYCSSTKLVNYKGKLGMINQEYVDDGGFPLKLSVWVLEDVGKEEWSTYVYTLRDDNKVDQVKYNLSVVGVTASGEIVLVKKTQTLKPFYVLYFNPDKNTLLTVEVKGLHRGLYAVHRIYAFVDHVEDLEFNIMKTTYAAKSKFSQEDRF
What are the official names of this protein?
Putative F-box protein At1g30920.
Protein: SODM1_BACCR
Sequence: MSLKWQYINWEEYNNGKTRIYQIYPYAYDALEPHFDKETMNIHHTKHHNTYITNLNAALEGHAELADKSVEELVANLNEVPEAIRTAVRNNGGGHANHTFFWTILSPNGGGQPVGELATAIEAKFGSFDAFKEEFAKAGATRFGSGWAWLVVNNGELEVTSTPNQDSPLTEGKTPVIGLDVWEHAYYLNYQNRRPDYIGAFWNVVDWNAAEKRYQEAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: G6PD_EMENI
Sequence: MSATIARAEEQQNGSTVELKDDTVIVVLGASGDLAKKKTFPALFGLFRNKFLPKGIKIVGYARTQMDHNEYLKRVRSYIKTPTKEIEEQLNSFCELCTYISGQYDQDDSFKNLAKHLEEIEKNQKEQNRVFYMALPPSVFITVSEQLKRNCYPKNGVARIIVEKPFGKDLQSSRDLQKALEPNWKEEEIFRIDHYLGKEMVKNILIMRFGNEFFNATWNRHHIDNVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPISFSAEDIRDEKVRVLRAMDPIQPKDVIIGQYGRSLDGSKPAYKEDDTVPQDSRCPTFCALVAHIKNERWDGVPFIMKAGKALNEQKTEIRIQFKDVTSGIFKDIPRNELVIRVQPNESVYIKMNSKLPGLSMQTVVTELDLTYRRRFSDLKIPEAYESLILDALKGDHSNFVRDDELDASWRMFTPLLHYLDDNKEIIPMEYPYGSRGPSVLDDFTASYGYKFSDAAGYQWPLTHTTPNRL
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: C8D11_ARATH
Sequence: MSSTKTIMETIYLILSLFFFFIFLSLKLLFGPRPRKLNLPPSPSRPFPIIGHLHLLKLPLHRRFLSLSESLNNAKIFSLSLGSRLVFVVSSHAVAEECFTKNDVVLANRPEFLVGKHIGYNSTTMVGAAYGDSWRNLRRIGTIEIFSSLRLNSFVSIRQDEIRRLIICLAKNSQHGFVKVEMKPLFMCLTINNIIRMVAGKRFYGDGTENDNEAKHVRQLIAEVVVSGGAGNAADYFPILRYVTNYEKHVKKLAGRVDEFLQSLVNEKRVEKVKGNTMIDHLLSLQETQPDYYTDVIIKGIILVMILAGTDTSAGTLEWAMSNLLNHPEVLRKAKTEIDDQIGVDRLVEEQDIVKLPYLQHIVSETLRLYPVAPMLLPHLASEDCIVDGYDVPRGTIILVNAWAIHRDPKLWEEPEKFKPERFEKKGEDKKLMPFGIGRRSCPGSGLAQRLVTLALGSLVQCFEWERVEEKYLDMRESEKGTTMRKATSLQAMCKARPIVHKVLDASCP
What is the function of this protein?
May play a role in cis-jasmone-activated defense response to aphids.
What are the official names of this protein?
Cytochrome P450 81D11.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS4_CHICK
Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: FLGI1_PHOPR
Sequence: MVPNLMVIKKHLIGLLLILCPLSLQAQPLFSVVDIQGIRENQLVGYGLVVGLSGTGDKSQTKFTSQSVKNMLSQFGVQLPANVNPKLKNVAAVAVNATLPALASKGQSLDITVSSIGDAKSLRGGTLLLTPLKGADGQIYAIAQGNLVVGGVVAQGNSGSGITINIPTAGLIPNGGIIEREVTSSFLTASTVVLNLKKPGFNTARNIEKEINELFGPDVALAQSHARIHVRAPHDPSQRVTFLAMLENLDIETGPRPARVVFNARTGTIVVGKNVKVHTAAVSHGNLTVSVMESFNVSQPNAFGRGNTAVTPETDVSIDQERGKVFIWPDSDEGTSLQTIVDAVNSLGATPNDLMAILIALDEAGALDGELVVL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein 1, Basal body P-ring protein 1.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: SLYX_PSEF5
Sequence: MSLQERVTDLESRLAFQDDTIQALNDVLVAQQRAVERLQLQMAALLKRQEEMVGQFESFEEEAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: NHP2_HUMAN
Sequence: MTKIKADPDGPEAQAEACSGERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNLPYVYIPSKTDLGAAAGSKRPTCVIMVKPHEEYQEAYDECLEEVQSLPLPL
What is the function of this protein?
Required for ribosome biogenesis and telomere maintenance.  Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs.  May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Protein: ZN844_HUMAN
Sequence: MDLVAFEDVAVNFTQEEWSLLDPSQKNLYREVMQETLRNLASIGEKWKDQNIEDQYKNPRNNLRSLLGERVDENTEENHCGETSSQIPDDTLNKKTSPGVKSCESSVCGEVFVGHSSLNRHIRADTAHKPSEYQEYGQEPYKCQQRKKAFRCHPSFQMQEKAHTGEKLYDCKECGKTFISHSSIQRHMIMHNGDGTYKCKFCGKACPCLSIYLIHERVHTGEKPYKCKQCGKAFSYSTSLQIHERTHTGEKPYECKECGKAFGSPNSLYEHRRTHTGEKPYECKQCGKAFRWFHSFQIHERTHSEEKAYECTKCGKAFKCPSYLCRHEVTHSGKKPCECKQCGKALSYLNFQRHMKMHTRMRPYKCKTVEKPLILPVRFEDMKELTLERNLMNASTVVKPSIVPVPFTIMKGLTLERNPMNVSSVVKPSFLPLPFDIMKGLTLERNRMSVSNVGKPSDLPHTFKCMEGLTLKRNPMNVSSVVKPSFFPLPFDIMKGLTLERNPMSVSNVGKPSHLPHTFKCMKGLTLESNCMNLNNVKKPLDLSETFKFMKRHTLERNPIRNMEKHSTISLPFKYMQQCTEDRMPMNVKSVTKHSYLPRSFEYMQEHTLERNPMNVRNAEKRSIIFLLCVYTKGCTLERNHINVRIVGKHSVCLVPFVDIKGLTLE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 844.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IL9R_MOUSE
Sequence: MALGRCIAEGWTLERVAVKQVSWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFTCLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPFDNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPLITSLSYELAFKRQEEAWEARHKDRIVGVTWLILEAVELNPGSIYEARLRVQMTLESYEDKTEGEYYKSHWSEWSQPVSFPSPQRRQGLLVPRWQWSASILVVVPIFLLLTGFVHLLFKLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQSWTGARRAGPQARQNGVSTSSAGSESSIWEAVATLTYSPACPVQFACLKWEATAPGFPGLPGSEHVLPAGCLELEGQPSAYLPQEDWAPLGSARPPPPDSDSGSSDYCMLDCCEECHLSAFPGHTESPELTLAQPVALPVSSRA
What is the function of this protein?
Plays an important role in the immune response against parasites by acting as a receptor of IL9.
What are the official names of this protein?
Interleukin-9 receptor, IL-9 receptor, IL-9R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: Y1722_RUMCH
Sequence: MLGPFEVLETIDMIQKENLDIRTITMGISLRDCCHPDIDISCKKIYDKITRYAEKLVVTGENIEREFGIPIINKRISVTPIALIAESSESDEYVKFAEAMDKAAQTVGVDFIGGFSSLVHKGYTVGDKRLIQSIPEALSRTKLVCSSVNVASTKAGINMDAVAEMGRIIKKCAELTADSGALACAKLVVFANAVEDNPFMAGAFHGIGEPECVINVGVSGPGVVKCALEKVKGADFGTVSETIKKTAFKITRMGQLVAQEASRRLNVPFGIVDLSLAPTPAIGDSVAYILEEMGLEKCGTHGTTAALALLNDAVKKGGVMASSYVGGLSGAFIPVSEDAGMIEAAMSGALSLEKLEAMTCVCSVGLDMIVVPGDTSAETISAIIADEAAIGVVNTKTTAVRIIPAPGKKVGDKVEFGGLLGSGPVMKVNPFSSSEFIKRGGRIPAPMHSLKN
What are the official names of this protein?
UPF0210 protein Ccel_1722.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: ISPG_NITEC
Sequence: MSSNNVPAPRRKCVGVKVGSVMIGGGAPIVVQSMTNTDTADELATVQQVEQLARAGSELVRITVNSMEAARTVPAIRARLDDMDCHVPLVGDFHFNGHKLLTAYPECAKALAKYRINPGNVGHGKKRDEQFSILIEMACKYDKPVRIGVNWGSLDPEMLARIMDENARSPDPLGASQVMHKALITSALESAARAEELGLGRDHIVLSCKVSGVQDLIAVYGELAAQCDYALHLGLTEAGMGSKGIVASTAALAVLLFKGIGDTIRISLTPEPGGDRAREVIVAQEILQTMGLRAFVPLVASCPGCGRTTSTYFQELAESIQIYVREQMIIWREQYEGVENMSLAVMGCVVNGPGESKHANIGISLPGSGETPVAPVFVDGQKTVTLKGDNIAGEFRVIVDEYVRTKYRKKVANA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: IGF2_NEOVI
Sequence: MGVPMGKSLLAPLTFLALASCCFAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSAQRLRR
What is the function of this protein?
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion.  Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_NITOC
Sequence: MVAPAPAKERIQALKELINNYDYAYYVVNNPLVPDSEYDRLIRELQALEENYPELITLDSPTQRVGAKPVKSLGEIKHEIPMLSLNNAFHEGELADFHRRVKTRLGIERVDYAAEPKLDGLAVSLLYQDGVLVQGATRGDGITGEDITHNIRTIPTVSLRLRGEKIPSLLEVRGEVYMPRQGFEQFNREQIAKGEKPFVNPRNAAAGSLRQLDPRITANRPLALFCYGVGQVEGGILPDRHSEILFQLKQWGLRILPYSEVVEELAGCEKYYQHLLDLRDKLPYEIDGVVFKVDYLDQQQILGSLARAPRWALAYKFPAQEELTQILDIEVQVGRTGALTPVARLQPVFVGGVTVSKATLHNEGEIQRKDIRIGDTVYVRRAGDVIPEIVKVIMERRLPDSRPFQMPRQCPVCGSEIVKEEGGAVARCSGGLYCPAQRKEAIKHFAGRRAMDINGLGDKLVEQLTKQGLLKDVADLYGLTKEQLAGLERMGQKSATNLINAIQQSKHTTLPRFLYALGIREVGEATAQVLAKEFGSLEALASVSEERLQQVTDIGPIVAAHIAAFFRQPHNRQIIQGLQKAGVCWPEVEDKVQIVQPLLGRTFVLTGTLESMTREQAKERLQALGGKVNGSVSPHTDYLIIGANPGSKLVKARNLGITILDETYFRNFLDDTSFP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GUAA_ALIFM
Sequence: MTTNIHDQRILILDFGSQYTQLVARRIREIGVYCELWSWDVEESDIRDFNPDGIILSGGPESVTEENSPRAPQYVFDSGVPVFGVCYGMQTMAEQLGGKVATSTEREFGYAAVQVTGESALFKDLEATQDVWMSHGDKVVEIPSDFVKIAETETCPYAVMANEEKKYYGVQFHPEVTHTKNGMKMLENFVLNVCGCEGLWTSASIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLAHRAIGDKLTCVFVDNGLLRLNEADQVMEMFGNKFGLNIIHVNAEQRFLDALEGESDPEVKRKIIGHVFVDIFDEESKKLKNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEIKKEYCDLLRRADAIFIEELHNADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGKVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: HERA_PYRFU
Sequence: MEEFVGIVRGEASFTSYEFSINPSANVSFGEFVVTKNRDGDLVLGTVRHVKNVNWLLSSVKSNFNSLALDIEEYGESLGENEEVVATVRILGKIEGNELVPNRVPIRNGEYVYKASDDLLQMIYGNDGIEIGTLLLRPNVRIKLDVNELVSRHFAVLAVTGAGKSNAVAVIIKGIVEDVGGTVVVLDPHGDYVNLRLPETGIDLVNIIDGKIRIEDLDPEELADLIGISSSAQIQRHFLSLAWETVKHKNQSLGGESLLEALLDLLNEWISRKTIKYWSEKEGRMKSEDLKSERIETIRGIIFRIRRFLRNYGNIVTSENLVAAIKPGMVNVIDLSPLDENQMKVVVGKFLEAVFEKRVEYEMARKRFEKETSKKKRDEYEEIMTEIESKYPALAYPILVIVEEAHIFAPQGEENDAMRIMGRIAREGRKFGVGLGVVSQRPSKLNEDILSQMNTKIILRIVNPRDQDYVLKASEQLSKDLMDDIAGLGKGEAVIVGQAIKLPALVRIYNFKELRGKAGTGQYGGEDIGILDRWNKMKRNMVNSLDIDIDF
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair (PubMed:18957200).  Acts probably with NurA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (PubMed:18957200).  Exhibits DNA-dependent ATPase activity and DNA helicase activity (By similarity) (PubMed:18957200).
What are the official names of this protein?
DNA double-strand break repair helicase HerA.
What is the protein family that this protein belongs to?
Belongs to the HerA family.
Protein: G3P_BOVIN
Sequence: MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFNGTVKAENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYNNTLKIVSNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDEIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Modulates the organization and assembly of the cytoskeleton.  Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks.
Protein: MURC_ACIF5
Sequence: MRNWVRQIHMVGIGGSGMRGIAEVLLNLGYAVSGSDLRPGNSTLRLTDLGARIFSGHEAANVRGADVVVISSAIPESNPEVQAARELRIPVIRRAEMLAELMRFKQGIAIAGTHGKTTTTSLVASILGAGGLDPTFVIGGRLKSAGTHAALGSGEYLVAEADESDASFLYLSPVMAVVTNIDADHMETYGGSLDNLRGAFLQFLQRLPFYGLAVLCTDEAVVAGLIPELRTPVLRYGFGADADLQARDVTVQGIGSRFAVWRRVDSDYVHWLDVELGIPGRHNVLNALAAIGIASKVGIPESTIATALADFRGVGRRFELVGTFDGITVVDDYGHHPREIAATIAAARSVWPERPLVVAFQPHRYSRTQALFADFVSSLAAADRVILTDIYSAGEKALPGVTGRALAEAMAAQGMSVRFLPDLLTAPQQIRAELPAGAVLLTLGAGSIASLAAQWPQVFGEDPS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_CHLAA
Sequence: MPEHILVAVAWPYANGPRHIGHVAGFGVPADIFARYHRLRGNHVLMISGTDEHGTPITLVADKEGTTPQAIADRYNKIIGDDLYNLGLSYDIFTRTTTANHYAVTQDIFRTLYERGYIIRQETLGAFSATTGRTLPDRYIEGTCPICGYDEARGDQCDNCGSQLDPTDLINPRSKVDGQPPVFKPTEHFFLDLPAFAEQLHAWIDRQTHWRPNVRNFSLNFLKELKPRAITRDLEWGVPIPLPEYVHRDDKKIYVWFDAVIGYLSASIEWARNSGQPDAWRTWWQNPAARHFYFMGKDNIVFHTVIWPAMLLGYGAGGDFGTDPSGTYQGVPLQLPYNVVSSEFLTMEGKKFSSSRGIVIYVNDFLSRYDADALRYFLTIAGPENQDTDFTWAEFVRRNNDELVATWGNLVNRTLTNVYKNFGSVPQPGPLTATDEQLIQEVNGGLETVGDLLATARFKAALSEAMRLAAQVNIYLSEQEPWKVIKSDRERAATIWYVALRCVDTLKIIFTPFLPFSSQRLHEYLGYDGYIAGPLSFRDVTEADGRVHRVLTGNYAEWVGRWQPSALPVGQALRQPQPLFKKLDEKVVDEELARMQSRAS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_PSEA8
Sequence: MSRLQTRFAQLKQENRAALVTFVTAGDPDYASSLEILKGLPAAGADVIELGMPFTDPMADGPAIQLANIRALDGGQTLARTLQMVREFRSGESETPLVLMGYFNPIHHYGVERFIAEAKEVGVDGLIVVDLPPEHNEDLCHPAQAAGLDFIRLTTPTTGDQRLPTVLEGSSGFVYYVSVAGVTGANAATLEHVEEAVARLRRHTDLPIGIGFGIRSAEHAAAVARLADGVVVGSALIDRIAKARDNAQAVKDVLALCGELAEGVRNAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ESPR_MYCTO
Sequence: MSTTFAARLNRLFDTVYPPGRGPHTSAEVIAALKAEGITMSAPYLSQLRSGNRTNPSGATMAALANFFRIKAAYFTDDEYYEKLDKELQWLCTMRDDGVRRIAQRAHGLPSAAQQKVLDRIDELRRAEGIDA
What is the function of this protein?
Virulence regulator that has both architectural and regulatory roles.  Impacts cell wall functions and pathogenesis through regulation of multiple genes.
What are the official names of this protein?
Nucleoid-associated protein EspR.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: G6PI_GEOUR
Sequence: MDKLHLWERYKSHLNVNPAIGLMLDISRMDFPDGFFNDIEQRMQKAFNDMAELEGGAIANQDERRMVGHYWLREPNLAPTGGLAAEIAFTLRGIKEFAAGVHDGTVTAPTGKRFMRMLVVGIGGSALGPQFVADALGSAADRLRPYFFDNTDPDGMDRVLAEIGASLRETMTIVISKSGGTKETRNGMLEAKRAYHAMGLEFAEHAVAVTGKDSELDKTAVREGWLARFPMWDWVGGRTSVTSAVGLLPAALQGIDIAALLEGARLCDEITRGRETRANPAALLALMWHHATAGRGAKDMVILPYKDRLLLFSRYLQQLIMESIGKERDLDGNIVNQGIAVYGNKGSTDQHAYVQQLREGVNNFFVTFIEVLQDREGKSMEVEAGVTSGDYLNGFFQGTRQALYENGRESLTITVDRLDARTIGALIALYERAVGYYASLVNINAYHQPGVEAGKKAAGVVLNLQGEVLSYLHRAQGMEFTAEEMAAAIGAEKEVETVFKILLHASANPGHGIAREAGETVFDWRFRSVR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_SULDN
Sequence: MLFDTPCIIFAGGKSSRMGEDKALLPFGSYDTLVEFQLYHLSKIFKTVYISCKEKSKFNFEAAFIEDIKTLPLYAPTAGFISVYNHLKSDNFFAISVDTPFITRSIIEKLLHVDKNTHDATIAKVNGLIQPMCGVYHRSLSEKFSQMLQNNSHKLGYLLKNSNTFYVEFEDEKSFFNLNHPHEYQEALALLNS
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.