PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_CLOBA
Sequence: MPNYRGGRINEEFKREISNIIQNEIKDPRLTAMISVTDVKVTKDLRYAKVYVSIFSTKEEEKKDNFTALKSASGFIRKILGQRINVRHNPEILFELDDSINYAMHIDELIQKVKDK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_ALKMQ
Sequence: MKEIVLAGGCFWGVEAYMERIDGVVETKVGYANGHVENPSYEEVCSSQTGHAEVCYIKFDETKISLEILLNGFWKIIDPTVENRQGPDIGSQYRTGIYYGHEEDLDTIIKSKEMQQKKYDANIVTEIEPLKAFYDAEEYHQKYLKKNPGGYCHINLEI
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: MSRQ_KLEP7
Sequence: MRFTVKQIVWLKVLLHLAGFLPLVWLFWAGHQGYFSADPAKDIQHFTGRMALKFLLATLLVSPLARYAKQPLLIRVRRLLGLWCFAWATLHLTSYTLLELGINNLALLGSEIITRPYLTLGMISWAILLALAVTSTQAMQRKLGRRWQLLHNFVYLVAILAPIHYLWSVKIVSPQPVVYALLAAGLLTWRYKKFRQWWRAIR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IQD16_ARATH
Sequence: MAKKNGTSWFTAVKKILWSPSKDSDKKTHHHKETDIKRKEKKGWIFRKTKLETTNSVLQHTVRTVEAEEKEKPPVIVSSVEEGVTEIVKLTATPGFIRRHWAAIIIQTAFRGYLSRRALRALKGIVKLQALVRGNNVRNQAKLTLRCIKALVRVQDQVLNHHQQQRSRVLLSPPSRNYNIEARRNSMFAESNGFWDTKTYLQDIRSRRSLSRDMNRCNNEFYSEETELILQKKLEIAIKREKAQALALSNQIRSRSSRNQSAGDDRELLERTQWLDRWMATKQWDDTITNSTNVRDPIKTLEAVTTHHHQRSYPATPPSCRASRSVMVRSASPRIPCSPSSMQPNYMSATESAKAKARTQSTPRRRPMTAKKRLCYAEEESLRSPSFKSCLWGDHESDYSCCYGDGFAGKISPCSTTELRWLK
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (PubMed:28115582).  Regulates cell shape and elongation in aerial organs (i. e.  cotyledons, leaves, and hypocotyls) probably by regulating cortical microtubules (MT) arrays orientation (PubMed:28115582).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 16, AtIQD16.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane. Note=Recruits calmodulin (CaM2) to microtubules.
Protein: ASSY_PSEPG
Sequence: MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANATGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEEMWRWSVSPENAPDQATYIELTYRNGDIVAINGVEKSPATVLADLNRIGGANGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVTVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRSLL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_STREM
Sequence: MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQGGLSQVSEAFILGSVSLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWLIIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLFGLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKDSGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKITYPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYLIKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTVIVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKRPKRAQVYWFVNVRVTDEPYTATYKVDMLGTDYIVCVELYLGFRMPQTVPRYLRTIVQDLMESGRLPKQVQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVTASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_LACGA
Sequence: MSSVIFLGTPNFGSVVLQGLIDQGYDVKAVVTQPDKRVGRKQVVHQSAVKQTALKHNLPVYQPAKLSGSDELAELMKIEPDFIVTAAYGQFLPTKFLKSAKIAPVNVHGSLLPKYRGGAPIQYSVLNGDKETGVTIMEMVKKMDAGDIFSQKALPIEDDDTSGTLFDKLSILGRDLLLETLPKFIDGTVTRTPQNEDKVVFSPNISKEQEQIKLTMTAEQANNLIRALNPDPGAYVMLDGKRFKIWKAKPLAEKTSFPAGTLVTNKKKFVISMAGGSELELLEVQPTGKKKMNIKDYLNGQGSHFTSGEKIIDE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: COAD_OENOB
Sequence: MVKAVFPGSFDPLTFGHLDVISRSALLFDQVIVAVGINTSKTAMFTTEEKITLISNNTKNLKNVSVLPMPDLTFKFVSSVGADVIVRGIRNVRDYEYERDIAEINHRLGNVDTVLLPSKAVYQDISSSNLKEVAKFGADISHFVPENVIKLIKLKTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEE_KORVE
Sequence: MQITEIYRSLQGESSYTGIPCIFVRLTACNLRCAWCDSEYTFKGGRKMSEDEIFAEVQKLAPGGLVEITGGEPLLQERELVPFMERLVASGYKVLIETSGERPLANVPQDVVKIVDVKCPASGEGGSFRIENLDALTPHDEIKFVISDRADYEFAREFTRQHGLENKVSSVIFSPAFRKDARGTRDASHCLVDPQDLANWVLEDQLDVRLGLQTHKFIWTPETKGV
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: RS15_SALDC
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: OTSA_MYCGI
Sequence: MTDQSGNGVRSGSASEAPPSAKADFVVVANRLPIDQVNLPDGSTEWKRSPGGLVTALEPLLRRRHGAWIGWPGVPEDADDPDASTEPIEQDGMTLVPVRLSAADVAKYYEGFSNATLWPLYHDVIVKPTYHREWWERYVEVNRRFAEAAARTAAEGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFLQMPWRTEIIEGLLGADLVGFHLPGGAQNFLILARRLLGAVTSRGNVGVRSRFGEVQFGFRKVKVGAFPISIDSAELDQHARTRATRQRAKEIRAELGNPRKVLLGVDRLDYTKGIDVRLRAFSELLEEGRIDPEDTVLVQLATPSRERVQSYIEMREDIERQVGHVNGEFGKVGHPVLHYLHRPIPREDLVAFFVAADVMLVTPLRDGMNLVAKEYVACRHDLGGALVLSEFTGAAAELRQAYLTNPHHLEGVKDAIEAALNQSPEEGRRRMRALRRQVLAHDVDRWARSFLDALASREPINEESH
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: PTND_ECO57
Sequence: MSEMVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACGLLGL
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ManXYZ PTS system is involved in mannose transport.
What are the official names of this protein?
PTS system mannose-specific EIID component, EII-M-Man, EIID-Man, Mannose permease IID component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_DESHY
Sequence: MARNFLTIALPKGKLLTDSLEALTKIGIECQEVSEESRKLVFPLEKAQAQIIICRPTDIPTFVEYGAADIGFVGKDTLLEENKDVVELLDLGFGYCRFVVAMPEEKVPPRLPDGRFDLSGLNHQRVATKFPRVAEDFFREQGMQVLPIKLHGNIELAPRVGLAEMIVDIVSTGTTLRQNKLVEIAPILEATTRLIANRVAYRMKHERINELTEKLRQLLGKAP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_ANAMM
Sequence: MSSAGGSSGPGYVLNDFDAVPRLSYAKSIDIRDSLTDLIRIQRDSYDAFIGIDRDGSSGIQSIFEAMFPIRDLLGRAVLEFVGYNIGEPQYDEYECIKRGITFSVPIRITLRFVVWKVQEVSFKEVKYVVDEDTSERSVKYMKEQEVSIGDLPMMTSYGTFIINGIERVIVSQMHRSPGVFFDSDKGKTYSSGKLIYSARVIPYRGSWLDFEFDIKDIIYFRIDKKRKLPVSYLLKALGMSNNDILDAFYDKVIYTRCDKGWRVPFIVDRFKGVRLSYDLMDVDGSVLVKANTRITLRIAKKLYADGLREYMVPFSGITGMFVAADLVDPSSGAVIVSAGETITSEHIVKLELFDISEIAFLNIDFLTVGPYVLNTLFLDKNMTQEDALFEIYRVLRSGESPNLDAVKSFFKGLFFESERYDLSVVGRIKLNSHLGLDVDENTTVLTKEDIVQVVKKLVLLRDGEGVVDDIDHLGNRRVRSVGEFIENQFRIGILRLERMIMDYMSSVNFDNAMPCDFVNPKVLATVLKDFFSSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGQNIGLISSLAIYAKINKYGFIESPYRKVENRVVTDKVEYLLAMQEGDYYIADAGAAIDENNRFVDDMLYCRHGGNFVMVKSEDVDYVDVSPKQIVSVAASLIPFLENNDANRALMGSNMQRQAVPLLKSEAPLVGTGMEFVVAAGSGAVVLAKRDGIVHRVDGSYIVIRAFDANKDECLGVDIYRLRKFQRSNHNTCINQRPVVKLGDYVKANDVIADGSAIDRGELALGKNVLVAFMSWQGYNFEDSIVISSDVVKRDVFTSIHIEEFECVVRDTPLGPEKIMRSVPDVNEESLSHLDDVGIVNIGAEVSASSILVGKVTPRPPVSLPPETKLLVTIFGEKVFDCVDSSLYLPPDVEGTVIDVHVFVRRGVEENDRSLLIKQSEISSFVKERDYEIDVVSEYFHDELRKLLRNAGVKVKGYSDLDSFFAEASDDTLWSTGLADAKVAAKVKDMRERFDSIVGEAHRKFEQKVDKLNYGYDLPQGVLTIVKVFVAVKHNLQPGDKMAGRHGNKGVISRIVPAEDMPHLEDGTPVDIILNSLGVPSRMNIGQILETHLGWAAVNLGKKIGRILDKGGPSMIADLRDFLDKIYDGQKLKSDIASMSSEALLVFANRLRKGVPMAAPVFEGPKDAQISKLLELAEVDPSGQVYLYDGRLGKKFDRKITVGYIYMLKLHHLVDDKIHARSVGPYGLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDIVGRVKIYESIIKGDSNFECGIPESFNVMIKELRSLCLNVVLKQDKEFTSGEVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: OXLA_GLOBL
Sequence: MNVFFMFSLLFLAALGSCADDRNPLEECFRETDYEEFLEIARNGLKATSNPKHVVIVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEGWYANLGPMRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKDPGVLKYPVKPSEEGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDMIGDLMNEDSGYYVSFPESLRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCTTSRATRRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGITTFTPYQFQHFSEPLTASVDRIYFAGEHTAEAHGWIDSTIKSGLRAARDVNRASEQ
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:11341935).  Shows activity on L-Leu (PubMed:11341935).  Exhibits diverse biological activities, such as apoptosis, and inhibition of agonist- and shear stress-induced platelet aggregation (SIPA).  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation.  These different effects are probably due to different experimental conditions.  This protein may also induce hemorrhage, hemolysis, edema, antibacterial and antiparasitic activities.
What are the official names of this protein?
L-amino-acid oxidase, LAAO, M-LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2665_MYCBO
Sequence: MTDSEHVGKTCQIDVLIEEHDERTRAKARLSWAGRQMVGVGLARLDPADEPVAQIGDELAIARALSDLANQLFALTSSDIEASTHQPVTGLHH
What are the official names of this protein?
Uncharacterized protein Mb2665c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1738.
Protein: RS17_RHOPS
Sequence: MPKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYKKTIRRSKNYHAHDENDQFHPGDMVWIEESKPISKLKRWTVVRGEPKKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NNR_LEIBR
Sequence: MLSRISERCTAVTGLEQVLCRHVWSAAWLRDAEPAAAASQSIDLSCLMERAGLAAYDVFASLYASQRHWLILVGSGNNGGDGYVIARHAREAGRKVTVLSMPHSKPLPTEATNAQHAWQAVGGTETMINPGTSLHLPTDVDLVVDGLLGTGISGPPREHYEEVIRHINALPVPRVAIDIPSGLNAETGEAAGACVKADHTATFICLKPGLLTGQARDYVGQLHYRSLGLEEWMIAAERMDAALCRRVALGDVYGYFSTRRSAVAHKGSCGKVVLIGGDHGFGGAILMSAEACLTIGAGLTRVLTRPEYVAPLLTRCPEVMVTAVETETSGQLEQQMVEAFEWASTLAVGPGLGTGAYGQAALSAALQQAEMHQDKTLVLDADALNLLAERLHSKEMGAAVGAGKYLPVLPNSIITPHPGEAARLLACRVADVEKDRLAAARRLAAILGGTCLLKGPGTVVHCQSSGKTAIVDAGNAGMASGGMGDVLTGLLAGLAAQRMMHDTFDTTCAAALVHGVAADMVAAEDGRGTRGIRATELIPRIPFIVNASVPSSATQQRPSGL
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: DSBE_SHIFL
Sequence: MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKPVPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVGMNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHAGDLNPRVWEEEIKPLWEKYSKEAAQ
What is the function of this protein?
Involved in disulfide bond formation.  Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbE, Cytochrome c biogenesis protein CcmG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: FES1_CHAGB
Sequence: MERNLNSLLKWSIENSVPSSAPAANGTNGTNGTTAVTTHSSDSNNTSTTPADAPSQTNGTSAAAANSKLNPEILSALFGGPSEAELMKAAMEVLTDKSATLDNQLIAFDNFEQLIESLDNANNLEPLKLWAPLLGLLAHDEAEMRRMAAWCVGTAVQNNARTQERLLAEGGLPILVGLATKEGEDVAVRRKAIYALSSAVRNCQPAMDAATAELSAHGKGDKVDAGDMDAVDGVIEWLRGEGERCVNGVKTFYDVGIGYQRRREERG
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_YERPP
Sequence: MNLISIPAFQDNYIWLLANRQKHCVIVDPGESAPVLATLAQGQYVPQAILLTHHHNDHVGGVADLRHHFPDIPVYGPQETAKKGATVIVNDGDSLTIAGQNYTIIAVPGHTLGHIAYYSSPYLFCGDTLFSAGCGRLLEGTPEQMYASIQRLAQLPDETLICCAHEYTLSNLKFAHAILPADQDIATYQQQIEQLRSKNLPSLPVKLQFERKINVFLRCNDIDLQRKIETTSPPDSLVSVFCELRSRKDSF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: SLTM_XENLA
Sequence: MASSDTTTERKKLADLRVIDLKTELKRRSLDVNGVKNVLMSRLKQAIEEEGGDPDNIELTVNSDTPKKNSKNKGRKVEADESGCEASVEEDSGKDNELESQDVSDQDGNDELKDSEENEEESATFVNVLSTEEENETKQTSHFDNPERGSDIQAEEAEEDEKKDVTGSGDVTQEISKPLHSGDNESELRIKEEMETSTSLKEAEDDNVSVTIQAEDAITLDCDGDDLLETGKNVKIADSETSKPKDEQEASYPKDGLEDQKDLTSENQKDDKEESGKGDAVKKDGREASKKTESGDKDKDSQKKGASSTGASGQAKSSSKDAKESKSASKEDKGSTSSTSGSSTRNLWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSADVARCISHLHRTELHGQQISVEKVKNDPSKRDIKKDGDEKLGSGRTSGERKSSGGDKNSKTQSSVKKDDRRSSDKAEKKDGKELKKDSKEKSESATTVPSPESSKKNEERKKPGGKSPGPMVVIDQTKGDQVYGRPPIRRGRFDKMRNREPFFQNKMKFREFRDRKDILTFEKMKQQRIREKVERMERIQRFRRAVEMRRSREMAERECRERERIRIMREREELDRLQRERERLEIERQKLERERMERERLERERIRIEQERRREAERIAREREELRRQQEQLRFEQEKRNSLKRPRDVDHRRDEPFWNENKKMAVDTDSRFSHGSDFNRQQNRFNDFDHRDRNRYSEGSNVSSFERRDRFVSPGEGKKGRPTMENFNKNFTDSRRNEPAQPRNDPRDTDRREVRDQDDRRPVGIERTGGNRNDGASHDRGRLGNPEIQHGRQRDSGNNQARSGTWKGEGGISADKREARGERTDRPTRESTGQPSRGGHASRGGKPGYTSRDGDRSVIVGERGSSGQHFNEGRQVVERHGRDAGGPRKDWHAPSSQGSGYNARRMSDGRSGGMMSSNPAINRVVQMPGGSMQRGSGSGFKSYKGAPQRRY
What is the function of this protein?
May act as a general inhibitor of transcription.
What are the official names of this protein?
SAFB-like transcription modulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: THOC7_MOUSE
Sequence: MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDDKLSEVDEAQESTMEADPKP
What is the function of this protein?
Required for efficient export of polyadenylated RNA.  Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.
What are the official names of this protein?
THO complex subunit 7 homolog, Ngg1-interacting factor 3-like protein 1-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Interaction with THOC5 is required for nuclear localization.
Protein: OTCC_HAEIN
Sequence: MAFNMKNRHLLSLVHHTEREIKYLLDLSRDLKRAKYAGTEQQKLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSSQIGHKESMKDTARVLGRMYDGIEYRGFKQSIVQELADYAGVPVFNGLTDEFHPTQMLADVLTMIEHCDKPLSEISYVYIGDARNNMGNSLLLIGAKLGMDVRICGPKALLPEANLVEMCEKFAKESGARITVTEDIDKAVKGVDFIHTDVWVSMGEPLETWGERIKLLLPYQVTPELMKRTGNPKVKFMHCLPAFHNSETKVGRQIAEKYPELANGIEVTEEVFESPMNIAFEQAENRMHTIKAVMVASLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTB_ECOSE
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPS_LEGPH
Sequence: MSKQNLEEIIQTGIADTELSTEISTAIKRPRKYKVLLLNDDYTPMDFVVEVLKHFFHLNEEVAIQVMLQVHFQGKGVCGVFTRDIAETKVALVNEYARMNQHPLLSSMEPE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.