PharMolix/UniProtQA huggingface dataset:
Protein: SYI_GEOSW
Sequence: MDYKETLLMPQTEFPMRGNLPKREPEIQKKWEEMDIYRKVQERTKGRPLFVLHDGPPYANGDIHMGHALNKILKDIIVRYKSMSGYCAPYVPGWDTHGLPIETALTKKGVDRKSMSVAEFRKLCEQYAYEQINNQREQFKRLGVRGDWENPYITLKPEYEAQQIKVFGEMAKKGLIYKGLKPVYWSPSSESALAEAEIEYKDKRSPSIYVAFPVKDGKGVLDGDEKIVIWTTTPWTIPANLAIAVHPDLDYQVVETNGAKYVVAAALLESVAKEIGWDEVTVVKTIKGKDLEYVVAKHPFYDRDSLVICGEHVTTDAGTGCVHTAPGHGEDDFIVGQKYGLDVLCPVDERGYMTSEAPGFEGLFYDEANKAITQKLEEVGALLKLSFITHSYPHDWRTKKPTIFRATTQWFASIDKIRGELLQAIKETKWIPEWGEIRIHNMIRDRGDWCISRQRAWGVPIPVFYGENGEPIITDETIEHVSNLFRQYGSNVWFEREAKDLLPEGFTHPSSPNGIFTKEIDIMDVWFDSGSSHQAVLVERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKAVLSHGFVLDGEGRKMSKSLGNVVVPAKVMEQLGADILRLWVASVDYQADVRISDSILKQVAEVYRKIRNTFRFMLGNLFDFNPETDAVPVNELREVDRYMIVKLNHLIENVKHAYETYDFASIYHDVNNFCTVDLSAFYLDFAKDILYIEAPNDRARRSIQTVLYETVVALTKLVAPILPHTAEEVWEHIPNRKEKEESVQLVDMPETINIDEEDAIVAKWDAFMNLRDDVLKALEVARNEKVIGKSLTASVTVYPTKEARQLLGSIEEDLKQLFIVSEFTIADDYEHAPEDAQKLANVAVIVKPAEGETCERCWVVTPEVGKDADHPTLCPRCAHIVKEHYSA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE067_HUMAN
Sequence: MKRIFYKHRKRRAPVFKEPEHGYQSLPELVLVPAQPLVCLGDYRTPDPGGLFPWSLRLMMPGAWTKLPGDGGSVPEKGKHGILGAQGQEHPGLNVSSPFSSPWTCYLSGHQPQNNNSPELQVKEILL
What are the official names of this protein?
Uncharacterized protein C5orf67.
Protein: FETP_SHEWM
Sequence: MARTVNCVYLKKEAEGLGFQLYPGPLGKRIFDNVSKEAWGLWQAKQTMLINEKKLNMMNVEDRGFLETQMVNFLFEGKDVEIEGYVPQKDDD
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: OSA15_ORYSJ
Sequence: MATRIPGTVAASGVYYNDQYRMPCKLKGIHCMALNCIPQKAKVRKCMNGYQSTFRFCVNEKNGQTTGQSNGSLIQQGQNFRCHSYGSHNSSETKECSLEDGTDSYRDFEEHSRGASQFSDNQVAAKKKSVKSSQGLAEACKFVYNDAKFVNERAQNDILLLSRGITRLNKRACQDVAVLGSGFLKLDARARKDTKKIDHSVKERAARLTHFARILKEQAQSDLKKAADQHWSDGALEADLRRADSVVRRRAMEDAFMALKFVRDIHDMMANRLQEQFAKDGSSSPANSRSFITLEKNGNTFELFPHEVSTDQITAIEQAYWSMASALSEADGIDYTDPEELELLVATLIDLDAMDGKKSVSLLAECSSSPDVNTRKALANALAAAPSMWILGNAGMGALQRLAQDSNYAVARAATRAINELTKQWELEEGDSLRFVLNQNMVSKETADDSAAADDTR
What is the function of this protein?
May be involved in the regulation of leaf senescence.
What are the official names of this protein?
Senescence-associated protein OSA15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ATA15/OSA15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYGA_STRP2
Sequence: MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAEVTYGLERLASYIQEVDSIYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFDKFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKRLGYPLLDEETRVKLLAEDAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_CHESB
Sequence: MFSASIERAQNEAPFPIRQGVFVAVAGPSGGGKDSVMAYARERLGNLAGEIVFARRIITRPFAPGGEEHDTRDVPTFEREEAAGAFALSWRANGLCYALPAALDEEMRSGGVVVANVSRAIIPALGERYAHIFPVIVTAPRGVLAERLSRRGRETRDEVLSRLARSEAGELDVPGALVIDNSGPLEQAGERFLEALRKAAAWSDVCDMV
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: CYB_RHIFE
Sequence: MTNIRKSHPLFKIINDSFVDLPAPSSISSWWNFGSLLGICLAIQILTGLFLAMHYTSDTATAFHSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGIYYGSYTFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWVWGGFSVDKATLTRFFALHFLLPFIIAAMVMVHLLFLHETGSNNPTGIPSDADMIPFHPYYTIKDILGLVLMLMALLSLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILILAAIPLLHTSKQRSMAFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPLASIAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GCSP_XANCP
Sequence: MSQTPSSLRDLEHHSAFVERHIGPNDAEIAQMLGVVGHDSLDAMTDAIVPSNIKSPAALALPDAITEEEALARIRAIASKNQVQRTFIGQGYYGTHTPKVILRNILENPAWYTAYTPYQAEISQGRMEALINFQTMCADLTGMQIANASLLDEATAAAEAMTLAKRSAKSKSDTFFVHDAVHPQTQELLRTRAEPLGIVLRVGTPDEAMQAECFGVLLQYPDSFGHIGDHAALADAVHAQGGLVAVATDLLALTLIAAPGEWGADIVVGNSQRFGVPFGFGGPHAAFMACRDAYKRSMPGRLIGVSIDAAGNPAYRLTLQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPEGLTRIARRTHRLAAILAAALRSAGVTVGEHFFDTLHVKAIDADAIHAKAHAAGINLRAIDSEAVGISLDETSTRADVVALAQLFGAQADIDALDAATADALPQGMRRTSAFLQHPVFNTHHSEHELLRYMRSLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWPEFGAIHPLAPPEQSAGYAQLIEELEAMLVECTGYDAVSLQPNSGAQGEYAGLLAIRAYHRSRNEAHRDICLIPESAHGTNPASAQMCGMTVVVTKCDANGNVDVDDIRAKAEKYSDRLAALMITYPSTHGVFEEDVVAICEAVHAHGGQVYTDGANMNALVGVAKPGKWGSDVSHLNLHKTFCIPHGGGGPGVGPCAVKSHLAPFLPKTLPNAGIRAGENQKAAIHGSGSNFGEGEVGMVSAASYGSASILPISWMYVTMMGSAGLRKATQVALLNANYIAKRLSAHYKTLYTGRNGLVAHECILDVRPLEKTSGIGAEDIAKRLIDFGFHAPTLSFPVAGTLMVEPTESESQHELDRFIDAMIQIREEIRAIEDGRLDREDNPLKHAPHTATQVSASEWTHAYPRELAAFPLPSLKQQKYWPPVGRVDNVYGDKNVMCACIPVDAYKDDVVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MTNB_BACCN
Sequence: MKQLFRKWHTLSELKKELTNRNWFPATSGNISIKVSHEPLTFLISASGKDKTKTTPDDFLLVDHQGNPVLETELRPSAETILHTHIYNHTNAGCVLHVHTTDNNVITNLYEKEVMIRNQEIIKALNIWEEGATIHIPIIENYAHIPLLGEAFKKHIQSDCGAVLIRNHGITVWGKDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSSGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: MALF_MALAU
Sequence: MKYTATFALLILAIGIQTQRRSTICRCRQEDACWPTTAEWSSLNQSIDGKLRHLRPVGLPCQQSAYHKEKCDEVLAMTHNSSWRVDHPESLQLVSWESWPEKNQSCQIVREAVDGCAQGRIPLYSAAVESTKQVQQAVSFAKHRNLRLVVRNTGHDMAGRSSAPGSLQILTSGLKGINYTENFVPFITQGSAEPMGPAVTIGAGILTGELYATGSEKGFVVLGGACSTVGIAGGFIQSGGMGILSPSKGLGSDHVLQVEIVTADGSHIIANQYQNEDLFWAVRGGGGGTFGVITSVTLRAFADLPATVTGIQINTPSADAIFWAGVKTVLSILPELTDAGNSARMIVLPASSTGGASASFEGYTFNKKGAVSLLALQRALDDFGIPFKLSHDFQGNLSRFLAAPKGVDLAGISVIPGSVFLSYDLVASKDGPAKVTSALSDLRLGPGSSFSVDAFGGGQVVNNKNRINSAVHPDWRSALLSLTVGRGVPPGYTLETLKSIESELENDQLPRLRSLEGGRKGAYLAVAYPNEVYFQDSFWGKNYDRLLKVKRAWDPEDLFITRVGVGSERWDDEGMCTRADSGLWHALARF
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of malbrancheamide, a dichlorinated fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core (PubMed:23213353, PubMed:31548667, PubMed:28777910).  The first step of malbrancheamide biosynthesis involves coupling of L-proline and L-tryptophan by malG, a bimodular NRPS, to produce L-Pro-L-Trp aldehyde through reductive offloading (PubMed:23213353, PubMed:31548667).  This compound undergoes spontaneous cyclization and dehydration to give a dienamine which is reverse prenylated at C-2 by malE (PubMed:31548667).  The other prenyltransferase present in the cluster, malB, displays modest activity, suggesting that may be a redundant gene in the pathway (PubMed:31548667).  Subsequently, a [4+2] Diels-Alder cyclo-addition catalyzed by the bifunctional enzyme malC forms the characteristic bicyclo[2. 2. 2]diazaoctane ring of premalbrancheamid (PubMed:31548667).  Finally, the flavin-dependent halogenase malA catalyzes the iterative dichlorination of the indole ring of premalbrancheamide to yield C-9 monochlorinated malbrancheamide B, C-8 monochlorinated isomalbrancheamide B, and dichlorinated malbrancheamide (PubMed:31548667, PubMed:28777910).  MalA is also able to brominate premalbrancheamide at C-9 to yield malbrancheamide C, and, to a lesser extend, at C-8 to yield isomalbrancheamide C (PubMed:28777910).  Finally, malA can brominate C-9 monochlorinated malbrancheamide B at C-8 to yield malbrancheamide D, or C-8 monochlorinated isomalbrancheamide B at C-9 to produce isomalbrancheamide D (PubMed:28777910).
What are the official names of this protein?
FAD-linked oxidoreductase malF, Malbrancheamide biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: DDI1_CRYNJ
Sequence: MRLTIIAPDSVHEHEVSPSLLIQDIINIVEATADLPPAVIVLTSDAGTPLTDPTRTLESYGLNGETATIFLTPTGPPVASSSSIPFPDADADIERMRLQALGNPSLMNDLRERDPETFAAIQGGTQSFKKALQLAQSRQRDAEFEKQRQIEALNADPYDIEAQKKIEEAIRMEAVLENMQHAMEYSPESFGNVTMLYINVEVNGHPVKAFVDSGAQTTIISPECAEQCGIMRLLDTRFAGMAEGVGTARILGRIHSAQIKLGSLYLPCAFSVLEGRSVDLLFGLDMLKRHQCCIDLSTNTLRINNTEVPFLSEHELPDKARRRGEAQVAGEMGDAAGQGVKAGVASPKIGKKTFPGEGHALGAGSSTGPGTATGSASATGARTGGTASVPSPSNRWKEDDIQTLVNLGAPRAQAIQLLEASGGNVDVAASMLFG
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFU1_DROPS
Sequence: MSKLLSYTARIILRNSRTTVRQLGQEGVRGFAGFVSGQRNAPQPAYGRPVPGLLRQKMVSSIGKRSMFIQTQDTPNPDSLKFLPGVEVLGKGNTYDFPSGTAAHCSPLAKLLFRVEGVRAVFFGSDFITISKEESAEWSLIKPEVFAVIMDFFASGLPILHEARPNADTEILDDDDETVMMIKELLDTRIRPTVQEDGGDIVFISYENGVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDDVDRMADKEFERFEKNLKQKEPAGAPVGIGGGPN
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.
What are the official names of this protein?
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ABP1_PHYPO
Sequence: LXAINDMDVAXNLMKVLNAVMRDPSLYRMXSLEAAMLNSFYATSYKPTFIDDXIMEQMMAFIDDDPLEQMRAERVVMYXTQPFIDAVVMYHNQLFIDAKSXLDSTRSYXXGG
What are the official names of this protein?
87 kDa annexin-binding protein.
Protein: ARLY_EHRCR
Sequence: MKNPLWGGRFTVSPSDIMKKINESISFDKILYEEDISGSIAHCKMLVNQKIISKYEGQLIIHGLEVIQNQISSGTFEFSTDLEDIHMNIEHHLKKMIGNIAGKLHTARSRNDQVATDFKLWIRKSIVKLETLLHELQQTILNIAEANYDTIMPGFTHLQIAQPVTLGHHLMAYFEMLKRDCSRWQDLHKRMNQCPAGSAALAGTSFPIDRHFIAQELKFDSPTENSIDAVSDRDYVIEFLSNASICIMHLSRLAEEIILWCSYNFKFITLSDNITTGSSIMPQKKNPDAAELIRGKTGRIFASLNQILVVMKGLPLAYSKDMQEDKEPVFDAANNLMLCIEAMNSMLNNITINKSNMLKAAEHDYSTATDLADWLVKNLNLSFRESHETTGQIVKLAEQNHCKLHELTLEQMKTIIPSITEDVFSILSVKNSVDSRTSYGGTAPANVIEAIKRGKLYLSNITTLHSENNM
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHL1_CANGA
Sequence: MDNATKFHHPYSPYDIQLDLMQCVYDTLANPVKKVAIVESPTGTGKTLSLICSTLTWLRDNKADILSSVDTLHSNEDDSHDSEPEWVKDTYKESILKDKLELLDEYEKYLEELHLKENKIIKFGTSIEDKSKVKRRKVTSSSKAKIEVSIEDEDEFVAKPYESDGEETTDLEKKEALSKEVQELLAKFDSSKKNTDNVELGRFASASQNQVRIFFSSRTHSQLNQFAEQLKLTNFPSSFPDKVAHERVKYMPLGSKKQLCINPDVKKWKTLEGINDACSEVRRSKEGCPFYQNTPKWHNSKETNHFRDQVFSDIHDIEDIAKVGESLAVCPYYAARDFIPSSEIVTLPYQYLLSESTRSQLRLDLKGSIVVIDEAHNLVDTINSIHSAEISLSELKQSYNSIILYMKKFKSRLNPGNRVNLLKLSKLITVLINFITTHYKKPGLEVDAFSILESNNTDMLNVHRVLKYIKTSHIAYKLDTYIQKLQEKESPSNQKPSSQPLLYKISKFLECLNNTSSEGSFFFERGPSLRYMLLEPSRIFQDIIDSARCVILAGGTMEPVSQLLQYLVPKLDDSSITKFSCNHVIPDSHLRTYIVNEPQFEFTFEKRNSVNLVQNHLFNFYLELSTTIPKTGGIIGFFPSYKYLDEIIVSWRKAGLFEKLDKERKVFYEMKDGPDPLPDYTSAVANSEGAILFAIVGGKLSEGINFGGNLCRAIVMTGLPYPNVFSGELIISRKHLEEKVLNGGGSKTDANMAAKEFFENICMKAVNQSVGRSIRSINDYSLIYLLDKRYANANIQSKLSQWVRSRIQSVSTVRDVMASSKEFFDQIADT
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COG2_HUMAN
Sequence: MEKSRMNLPKGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDKALNQLSVPLGQLREEVLSLRSSVSEGIRAVDERMSKQEDIRKKKMCVLRLIQVIRSVEKIEKILNSQSSKETSALEASSPLLTGQILERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSDVDIIRHCLRTYATIDKTRDAEALVGQVLVKPYIDEVIIEQFVESHPNGLQVMYNKLLEFVPHHCRLLREVTGGAISSEKGNTVPGYDFLVNSVWPQIVQGLEEKLPSLFNPGNPDAFHEKYTISMDFVRRLERQCGSQASVKRLRAHPAYHSFNKKWNLPVYFQIRFREIAGSLEAALTDVLEDAPAESPYCLLASHRTWSSLRRCWSDEMFLPLLVHRLWRLTLQILARYSVFVNELSLRPISNESPKEIKKPLVTGSKEPSITQGNTEDQGSGPSETKPVVSISRTQLVYVVADLDKLQEQLPELLEIIKPKLEMIGFKNFSSISAALEDSQSSFSACVPSLSSKIIQDLSDSCFGFLKSALEVPRLYRRTNKEVPTTASSYVDSALKPLFQLQSGHKDKLKQAIIQQWLEGTLSESTHKYYETVSDVLNSVKKMEESLKRLKQARKTTPANPVGPSGGMSDDDKIRLQLALDVEYLGEQIQKLGLQASDIKSFSALAELVAAAKDQATAEQP
What is the function of this protein?
Required for normal Golgi morphology and function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein.
What is the protein family that this protein belongs to?
Belongs to the COG2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS19_ACAM1
Sequence: MSRSLKKGPFVADHLLTKVENLNEKGEKQVIKTWSRASTIIPQMIGHTIAVHNGRQHVPVYVSEQMVGHKLGEFAPTRTFKSHSKGDKKARM
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NEAP3_ARATH
Sequence: MPTSVSLREDDPLLKDLSEKKQSFRRNVVSLATELKEARTRLAEQERSCSKEAMSRQEAETRVKRMEDEMHELAKELNEKVEQIRASDVATEKFVKELADIKSQLAATHATAEASALSAESAHSHCRVLSKQLHERTGSLKEHEDQVTRLGEQLENLRKELRVRESSQKQLRDELLKVEGDIMRAVSVVKTKENSEVRNMLNEDTPKNSERINKLLTAKDDEIARLRDELKIISAHWRFKTKELEDQVENQRRIDQELKKKVLKLEFCLRETRIQTRKLQKMGERNDVAIQELKEQLAAKKQHEADHSSNQNLWDKSGFKIVVSMSMLILVAFSRR
What are the official names of this protein?
Nuclear envelope-associated protein 3, AtNEAP3.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein. Nucleus, nucleoplasm.
Protein: SRXN1_HUMAN
Sequence: MGLRAGGTLGRAGAGRGAPEGPGPSGGAQGGSIHSGRIAAVHNVPLSVLIRPLPSVLDPAKVQSLVDTIREDPDSVPPIDVLWIKGAQGGDYFYSFGGCHRYAAYQQLQRETIPAKLVQSTLSDLRVYLGASTPDLQ
What is the function of this protein?
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 (PubMed:15448164, PubMed:15590625).  Does not act on PRDX5 or PRDX6 (PubMed:15448164, PubMed:15590625).  May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (PubMed:15448164, PubMed:15590625).
What are the official names of this protein?
Sulfiredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the sulfiredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET3_PICGU
Sequence: MDFELEPTLESIVEHDSLKWIFVGGKGGVGKTTTSSSIAVQLALSKPNDQFLLISTDPAHNLSDAFCQKFGKDARPVEGLPNLSCMEIDPEAAMSDLQQQASQYNNDPSDPMKNIMNDMTGSIPGIDEALSFMEVLKHIKNQKASDGDSDEKTVAYKTIIFDTAPTGHTLRFLQLPATLEKLLGKFKQLSGKLGPMLNMLGGGQQQDIFEKMNEIQKNVSEVNEQFTNPDLTTFVCVCISEFLSLYETERMIQELVSYNMDVNSIVVNQLLFADNDGSCKRCASRWKMQQKYLDQMAELYEDYHVVKMPLLGTEVRGIDNLKKFSKFLLSPYDPEKDGSLVFDMEEK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: GPMB_ECOLC
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: YEAL_SALA4
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFPWIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATY_ECOSM
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAASMHAPVIIAGTPGTFTHAGTENLMALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPVQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKFAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: LIVM_METJA
Sequence: MSIDLISMILLWFGLYYIVSLSLNMEFGYAGIPNFGKALSVLVGAIAVGGILDRLLMLYFGIGGDFITGTTYATSAINNLIASNPIVGIGILILAIILASILGFVVGAIFILPSAKLKEDYLGITLLAISEAVLLICTYNLNIIGGYYGISTPDILAFVSGEYRGWVFAWIVLFIAFLVYLFFERLLNTPFGRVLRAMRENENTVKAFGRDIMKLRIKTMAIGSAIGAIAGVLYSLYTVNIIANAFTRVDWTFFPFLMVLLGGKGNNKGVALGVLCYVIVKVLLDIYKYNIKYALGIPFEPVWLSYMLFGVLMLLILYYKPSGLIPEKPIITPPMKKKIMEISGK
What is the function of this protein?
Part of the binding-protein-dependent transport system for branched-chain amino acids.  Probably responsible for the translocation of the substrates across the membrane (By similarity).
What are the official names of this protein?
Probable branched-chain amino acid transport permease protein LivM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSD3B_ARATH
Sequence: MTQDVEMKDNQTPTQSVVSAPTSTLQNLKEIAALIDTGSYTKEVRRIARAVRLTVGLRRKLTGSVISSFLDFALVPGSEAHTRLSSFVPKSDEHDMEVDTASSNSQAPPKHLPAELEIYCYFIVLLFLIDQKKYNEAKVCSTASIARLKSVNRRTVDVIASKLYFYYSLSYELTNDLAEIRSTLLALHHSATLRHDELGQETLLNLLLRNYLHYNLYDQAEKLRSKAPRFEAHSNQQFCRYLFYLGKIRTIQLEYTDAKESLLQAARKAPVASLGFRIQCNKWAIIVRLLLGEIPERSIFTQKGMEKTLRPYFELTNAVRIGDLELFGKIQEKFAKTFAEDRTHNLIVRLRHNVIRTGLRNISISYSRISLQDVAQKLRLNSANPVADAESIVAKAIRDGAIDATIDHKNGCMVSKETGDIYSTNEPQTAFNSRIAFCLNMHNEAVRALRFPPNTHREKESEEKRREMKQQEEELAKYMAEEDDDDF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 3 homolog B, 26S proteasome regulatory subunit RPN3b, AtRPN3b, 26S proteasome regulatory subunit S3 homolog B.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.