PharMolix/UniProtQA huggingface dataset:
Protein: K1C25_SHEEP
Sequence: MSLRLPSGSRRAGPRPTTGSLRLSGAGASFGAGNACSMPGIGSSFSCAFGSSSSGGNALGGNPCAGFTMNEGGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYLPIIEDLKNQIIASTTSNANAVLQIDNARLTADVFRLKYENELALHQSVESDVNGLRRVLDVITLCRTDLEIQYETLSEELTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQITEDVGATTSARNELTEMKRNLQTLEIELQSLLATKHSLECSLTETEGNYCAQLAQVQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYAAGNMGNQMKDPIRAIVVKKVLEEVDQRSKVLTTRLHSLEEKSQSN
What is the function of this protein?
Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity).  Plays a role in the cytoskeleton organization (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 25, Cytokeratin-25, CK-25, Keratin-25, K25, Type I inner root sheath-specific keratin-K25irs1, Type I keratin intermediate filament IRSa1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM_RENRE
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGDGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: DNJC2_MACFA
Sequence: MLLLPSPADGRGTAITHALTSASTLCRVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFAMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDLQKKAIKKERQKLRNSCKTWNHFSDNEAERVKMMEEVEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEAHMRQASKNTEKSAGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNAAPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRAKK
What is the function of this protein?
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus.  When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.  In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain.  When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
What are the official names of this protein?
DnaJ homolog subfamily C member 2, Zuotin-related factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: MAP2_PYRHO
Sequence: MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIESRIVELGGKPAFPANLSLNEVAAHYTPYKGDQTVLKEGDYLKIDLGVHIDGYIADTAVTVRVGMDFDELMEAAKEALESAISVARAGVEVKELGKAIENEIRKRGFNPIVNLSGHKIERYKLHAGVSIPNIYRPHDNYVLQEGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMAQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRSLERSGALYGYPVLREIRGGMVTQFEHTIIVEKDSVTVTTE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
Protein: ISPE_CHLTR
Sequence: MHFLSPAKLNLFLQILGRREDDFHEIVTRYQAIAFGDQLSLSISSRDSLQVINACHLETPSNSIWKSVALFRRYTGITTPVSWRVVKQIPVGAGLAGGSSNAATALFALNQIFKTGLSDEEMRSLAEQLGVDTPFFFSTGAALGVARGEKIIALEESVSDRYVLYFSSEGVLTSRAFAAVQPSDCSSRKNLEYTQNDLEKPVFRLRLDLKEKKHWLENLWAELPVHIGLTGSGATLFVRYPEILEEDLSYAAQIQRAVTLSGGLLTSPIRRDPTAWYSIYSESALAAT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CUTA_THEMA
Sequence: MILVYSTFPNEEKALEIGRKLLEKRLIACFNAFEIRSGYWWKGEIVQDKEWAAIFKTTEEKEKELYEELRKLHPYETPAIFTLKVENVLTEYMNWLRESVL
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_VIBCM
Sequence: MRIIGIETSCDETGIAIYDDEKGLLSHKLYSQVKLHADYGGVVPELASRDHVKKTIPLIKAAMAEANVTPQDLDGVAFTAGPGLVGALLVGATIGRSLAYAWDVPAVPVHHMEGHLLAPMLEENPPPFPFVALLVSGGHTMLVEVKNIGEYRILGESIDDAAGEAFDKTAKLMGLDYPGGPLLAKLAEKGTPGRFKFPRPMTDRPGLDMSFSGLKTFTANTIAANGDDEQTRADIAYAFQEAVCDTLVIKCKRALEETGLKRVVIAGGVSANKQLRADLEKLAKKIGGEVYYPRTEFCTDNGAMIAYAGMQRLKNGDVCELGLQARPRWPIDQLTSIQK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR16_CHICK
Sequence: MAGFVPLLLLLLPAGPTWGSKEKCLTKMYTTSGECCKACNLGEGVVQPCGVNQTVCEPCLDSVTYSDTVSATEPCKPCTQCVGLHSMSAPCVESDDAVCRCAYGYFQDELSGSCKECSICEVGFGLMFPCRDSQDTVCEECPEGTFSDEANFVDPCLPCTICEENEVMVKECTATSDAECRDLHPRWTTHTPSLAGSDSPEPITRDPFNTEGMATTLADIVTTVMGSSQPVVSRGTADNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANNRPVNQTPSPEGEKLHSDSGISVDSQSLHDQQPPNQSTQGPAPKGDGSLYASLPPSKQEEVEKLLSSSAEETWRQLAGELGYKEDLIDCFTREESPARALLADWSAKETATLDALLVALRKIQRGDIAESLYSESTATSPV
What is the function of this protein?
Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4.  Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (By similarity).  Plays an important role in differentiation and survival of specific neuronal populations during development (By similarity).  Can mediate cell survival as well as cell death of neural cells.  Plays a role in the inactivation of RHOA (By similarity).  Necessary for the circadian oscillation of clock genes in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, dendritic spine.
Protein: EFTU_CORK4
Sequence: MAKAKFDRSKPHVNIGTIGHVDHGKTTTTAAITKVLSEKYPEENQAFAFDAIDKAPEEKERGITINIAHVEYSTPKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKCDMVDDEDLIELVEMEVRELLAEQDFDEDAPIVHISALKALEGDEKWEQSILDLMDACDESIPDPVRETDKPFLMPIEDIFTITGRGTVVTGRVERGKLNINDDVEILGIKEKSQNTTVTGIEMFRKQLDYAEAGDNCGLLLRGTKREDVERGQIVAKPGAYTPHTEFEGSVYVLSKDEGGRHTPFFDNYRPQFYFRTTDVTGVVKLPEGTEMVMPGDNVDMSVTLIQPVAMDEGLRFAIREGGRTVGAGRVTKINK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_SHEFN
Sequence: MNALTEMKCEACQADAPKVTDAELAELVGMIPDWGVEIRDGIMQLERVYKFKNFKLAMAFTNKLADLAEAEFHHPGILTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PP405_ARATH
Sequence: MSEVLRRANNALSSVKQYQSLLNHFAATQSISKTKALHCHVITGGRVSGHILSTLSVTYALCGHITYARKLFEEMPQSSLLSYNIVIRMYVREGLYHDAISVFIRMVSEGVKCVPDGYTYPFVAKAAGELKSMKLGLVVHGRILRSWFGRDKYVQNALLAMYMNFGKVEMARDVFDVMKNRDVISWNTMISGYYRNGYMNDALMMFDWMVNESVDLDHATIVSMLPVCGHLKDLEMGRNVHKLVEEKRLGDKIEVKNALVNMYLKCGRMDEARFVFDRMERRDVITWTCMINGYTEDGDVENALELCRLMQFEGVRPNAVTIASLVSVCGDALKVNDGKCLHGWAVRQQVYSDIIIETSLISMYAKCKRVDLCFRVFSGASKYHTGPWSAIIAGCVQNELVSDALGLFKRMRREDVEPNIATLNSLLPAYAALADLRQAMNIHCYLTKTGFMSSLDAATGLVHVYSKCGTLESAHKIFNGIQEKHKSKDVVLWGALISGYGMHGDGHNALQVFMEMVRSGVTPNEITFTSALNACSHSGLVEEGLTLFRFMLEHYKTLARSNHYTCIVDLLGRAGRLDEAYNLITTIPFEPTSTVWGALLAACVTHENVQLGEMAANKLFELEPENTGNYVLLANIYAALGRWKDMEKVRSMMENVGLRKKPGHSTIEIRSNSVDTR
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g39350.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: GPMA_MYCBT
Sequence: MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVKHLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAAVAGQGRG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RECO_RHIEC
Sequence: MQWQDQAIILGVKRHGETSVIAEVMTRGRGRHLGLVRSGRSRAMRPVLQPGNAVEVVWRARLDEHLGEFRVEPVTLRAARLMDTATAVYGVQAMGALLRLLPERDPHPHLFDALEVILDHLHNPADAGELFVRFELAVLNDLGFGLDLAECAATGARSDLAYVSPKSGRAVSRSAGAPWADKMLLLPPFLGVEGNHAADVDSLAAAFRLTGFFLHRHVYEPRGIEAVAARDGFVQAALKALNPASQTLSSPNGVSA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: IL10_FELCA
Sequence: MHSSALLCFLVFLAGVGASRHQSTLSEDNCTHFSVSLPHMLRELRAAFGKVKTFFQTKDELHSILLTRSLLEDFKGYLGCQALSEMIQFYLEEVMPQAENEDPDIKQHVNSLGEKLKTLRLRLRRCHRFLPCENKSKVVEQVKSTFSKLQEKGVYKAMGEFDIFINYIEAYMTMKMKI
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: F187A_HUMAN
Sequence: MHLALTTVLLWAWGLQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFELPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDMLTRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATFQDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDLSPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIREGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGVLVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRCCCYLFHCCPSFSP
What are the official names of this protein?
Ig-like V-type domain-containing protein FAM187A.
What is the protein family that this protein belongs to?
Belongs to the FAM187 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YY06_CAEEL
Sequence: MLETEHANTEVHELCRQMIARIEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCEHGLIVDLIWSDPNRKDDTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNKGYDRSKLDKRTLHDFEKNFQPLDENPRKNISCQFNVPPNGQKMSPFLGEYSMFAHETQFCKKDNETPVKKPYSSNQDEDHSVLDMIRKTQKGYGVEVSLKDKVMSLESIRKKLGMTTSTTPPPPRTPSPDAPLAQSPPIPRSPPSSTENA
What are the official names of this protein?
Putative serine/threonine-protein phosphatase C27B7.6.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: PSAC_PROMA
Sequence: MSHSVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSVRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SDHF3_BOVIN
Sequence: MSALHVSRVRALYRRILLLHRVLPPDLKDLGDRYVKDEFRRHKTAGSKEAERFLQEWEAYAAVLWQQANESRQNSTEKACFGISLPEEKLNDFRDEQIGQLQELMQEATKPNRQFNITESRKPKL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ITPK2_ORYSI
Sequence: MRLHGEVSFDEDEEEVVMVPAAALSSSPLNGGAVPVTRLVVGYALTKKKVKSFLQPNLLLLARKKGINLVAIDDTRPLAEQGPFDVILHKITSKEWQQVLEDYHEEHPEVTVLDPPNAINHLNNRQSMLAEVSDLNLSSFYGEVCTPRQLVIMRDPSSIPTAVAMAGLTLPLVAKPLVVDGTSKSHELSLAYDEASLSMLDPPLVLQEFVNHGGILFKVYIIGETIQVVRRFSLPDVNTYDLLNNVGVYRFPRVSCAAASADHADLDPHISELPPRPLLEKLGKELRGRLGLRLFNIDMIRELGTKDRYYIIDINYFPGFGKMPGYEHIFTDFLLNLAQSKYKKCLSGG
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and participates in phytic acid biosynthesis in developing seeds.  Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase 2, Inositol 1,3,4-trisphosphate 5/6-kinase 2, Inositol-triphosphate 5/6-kinase 2, Ins(1,3,4)P(3) 5/6-kinase 2, OsITP5/6K-2, OsITPK2.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
Protein: FABA_RHOP5
Sequence: MQDRRSSYDYEDLLACGRGEMFGPGNAQLPLPPMLMFNRITEINDNGGEYGKGLIRAELDVTSDLWFFGCHFKGDPVMPGCLGLDAMWQMVGFFLGWTGGEGRGRALGLGELKFTGQVLPDIRKVVYNIDVKRVMRSKLVLGIADGWLSADDTIIYRAKELKVGLFKQDAAVPAGG
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SULNB
Sequence: MANLKEIKRKISSVKNTQKTTNAMKLVSSAKLKRTEELAKRSRVYAAKLTELIEEIAQKMQHASAEGLDNIFFQENNNPKKVDIIFITADKGLCGGFNSQTIKRTSQMIAEYQSKGAKVRLRAIGRKGIDYFKFNNVELDDAIVGLSAAPDYKQSSEFISEVVTSYVNGDTDRIVLVHNGYVNMITQEIREDQILPVDASQLELSTVSTSEMEVEPDDDDTLLDALVKRYVEYSIYYALIDSLAAEHSARMQAMDAATKNAKEMVKDLNVKYNKARQEAITTELIEIISGMESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARGR_YERPP
Sequence: MRNPAKQEDLIKAFKALLKEEKFSSQGEIVLALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDVDYNDSVVVINTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKQLHEAILRLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5507_BACC4
Sequence: MGNEFRVCDDCQATNVKTLVPKLKKVDSCATIEVGCQSYCGPGRKKSFAFVNNRPVAAPTEDELIVKIEAKLNK
What are the official names of this protein?
UPF0741 protein BCB4264_A5507.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: SP152_IXOPE
Sequence: MKVVCIIVLFVIVAVNESATSEANTSNAAKDTKKKNVTLQFPSYIQNPKQLALELLKICKNNKSSHNSLTSRSSYNYYAINDKYVDFKNCTFLCKHDKDINVTLNMPPNTPCGPNGQTCADKSQCVGHIPGC
What is the function of this protein?
Salivary tick protein that downregulates host immune system by binding to both dendritic cells, and CD4(+) T cells.  Specifically binds to the CD4 coreceptor on T cells.  This interaction prevents the activation of the Src kinase, Lck, and its downstreamsubstrate Zap-70, and results in deficient activation of PLCgamma1, the repression of calcium fluxes triggered by T-cell antigen receptor (TCR) ligation, and a subsequent reduction in interleukin-2 production.  This salivary protein also binds to DC-SIGN (CD209) on dendritic cells (DC) and activates the Raf-1 kinase/MEK signaling pathway that results in down-regulating expression of pro-inflammatory cytokines.  Furthermore, it inhibits T cell proliferation induced by DCs (By similarity).  It also inhibits in vitro keratinocyte inflammation induced by Borrelia burgdorferi or by the major outer surface protein (OspC) of Borrelia.  In addition, it downregulates chemokines and monocyte chemoattractant protein 1, as well as several antimicrobial peptides such as defensins, cathelicidin, psoriasin, and RNase 7 (By similarity).  Apart from its immunomodulatory activities, it is also associated with protection of Borrelia spirochetes from antibody-mediated killing through its binding to OspC.  In vivo, tests on different immune disease animal models show promising therapeutic results, e. g. , in inhibiting HIV infection, experimental autoimmune encephalomyelitis, transplantation rejection, and asthma (By similarity).
What are the official names of this protein?
Salivary protein 15 Iper-2, Salp15 Iper-2, Salp15-like.
What is the protein family that this protein belongs to?
Belongs to the salp15 family.
Protein: Y1339_METJA
Sequence: MKKDEVKVVVIGSSDVGKTTLMENLIDKIGKVEYKGITTAIDYGSLTIKDKKIHFFGTPGQKRFEFMRELALKGTNFALVVLDASKGITKEDEEIIKLLESKKIPYGIFINKTDVGDIDTSEVYNFCNPKFIVKGCAVKKDGLDELINKIMSHT
What are the official names of this protein?
Uncharacterized protein MJ1339.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH765.
Protein: MGSA_CITK8
Sequence: MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEKHELYATGTTGNLIQRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNASTADFIVQSPHFNDAVDILIPDYQRYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: MP_SSVN
Sequence: MDSFGRAPPLWPQSALPRVPGAAPSSSGLPWSRVGEIAIFTFVAVLALYLLWSWVGRDLLLVLKARRGGTTEELTFGPRERHSLPAVAVARVENPPCPSGSVEARPFTG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y1249_PROA2
Sequence: MENNRAGRPKSCRRVKEMPKVRCFKPQGIPGIKLEEMVLSVDEMESLRLADLEGLYQSEAARRMDVSRQTFGRIIDSAHRKVADAIIHGKSIVIEGGVVMKREEQVHNAKPGCVCQHCGHEESHRSGLPCRDMICPECGHHMIRKGGCGTGQEDI
What are the official names of this protein?
UPF0251 protein Paes_1249.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.