PharMolix/UniProtQA huggingface dataset:
Protein: CAS9_CAMJE
Sequence: MARILAFDIGISSIGWAFSENDELKDCGVRIFTKVENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNSDDKEKGAILKAIKQNEEKLANYQSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGEHNLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKKYGKVHKINIELAREVGKNHSQRAKIEKEQNENYKAKKDAELECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKISDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNQTPFEAFGNDSAKWQKIEVLAKNLPTKKQKRILDKNYKDKEQKNFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSAKDRNNHLHHAIDAVIIAYANNSIVKAFSDFKKEQESNSAELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein.  The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA.  Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA).  Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs.  PAM recognition is also required for catalytic activity (By similarity).  Cuts target DNA in Cas9:gRNAs mixing experiments with N. meningitidis strain Z2491 and P. multocoda strain Pm70.
What are the official names of this protein?
CRISPR-associated endonuclease Cas9.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas9 family. Subtype II-C subfamily.
Protein: TAL_BACCZ
Sequence: MKFFIDTANINEIKEANALGVLAGVTTNPSLVAKEGVDFHERIREICNVVEGPVSAEVISLEADKMIEEGKELAKIAPNVVVKVPMTTEGLKAVKAFSDLGIRTNVTLVFSAVQALLAARAGATYVSPFLGRLDDIGHNGMDLIRQIAEIFAIHGIETEIIAASVRHSVHVTDAALNGAHIATIPANVIASLVKHPLTDQGIEKFLADWEKTQEK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN_ALKA3
Sequence: MMLRKKTKQLISSILILVLLLSLFPTALAAEGNTREDNFKHLLGNDNVKRPSEAGALQLQEVDGQMTLVDQHGEKIQLRGMSTHGLQWFPEILNDNAYKALANDWESNMIRLAMYVGENGYASNPELIKSRVIKGIDLAIENDMYVIVDWHVHAPGDPRDPVYAGAEDFFRDIAALYPNNPHIIYELANEPSSNNNGGAGIPNNEEGWNAVKEYADPIVEMLRDSGNADDNIIIVGSPNWSQRPDLAADNPIDDHHTMYTVHFYTGSHAASTESYPPETPNSERGNVMSNTRYALENGVAVFATEWGTSQANGDGGPYFDEADVWIEFLNENNISWANWSLTNKNEVSGAFTPFELGKSNATSLDPGPDQVWVPEELSLSGEYVRARIKGVNYEPIDRTKYTKVLWDFNDGTKQGFGVNGDSPVEDVVIENEAGALKLSGLDASNDVSEGNYWANARLSADGWGKSVDILGAEKLTMDVIVDEPTTVSIAAIPQGPSANWVNPNRAIKVEPTNFVPLEDKFKAELTITSADSPSLEAIAMHAENNNINNIILFVGTEGADVIYLDNIKVIGTEVEIPVVHDPKGEAVLPSVFEDGTRQGWDWAGESGVKTALTIEEANGSNALSWEFGYPEVKPSDNWATAPRLDFWKSDLVRGENDYVTFDFYLDPVRATEGAMNINLVFQPPTNGYWVQAPKTYTINFDELEEPNQVNGLYHYEVKINVRDITNIQDDTLLRNMMIIFADVESDFAGRVFVDNVRFEGAATTEPVEPEPVDPGEETPPVDEKEAKTEQKEAEKEEKEE
What are the official names of this protein?
Endoglucanase, Alkaline cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: RLMG_SHIFL
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEILGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRSEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHYARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH13_DANRE
Sequence: MDWSEGDGSHSHGHMGDSCHGHGGGHSHGHGHSHGGSGFGGFMPAGFHGQLVPGPMDPTQQPRKSSHPEDSSSWDIIKATQFGALERCKELVEAGYDVRQPDKENVTLLHWAAINNRADIVKYYISKGAVIDQLGGDLNSTPLHWAIRQGHLSMVIQLMRYGADPSLADGEGYRGLHLAVLFQNMPIAAYLMAKGQEVDLPDLNGQTPLMLAAQKIIGPEPTNFLIKCNASVNAVDKVNRNSPLHCAVLAGNVDSVHILLEAGASVDMQNDNGHTAIDLAQQVHSPLLIHMLSVVKTERIKANSACLKLLNRYKVCLQSVFSVVVVGAFGAILDMRTESWLLKGILLACIMAVINLASRQLATVAVRSLIPSTGLIASVFWMVVTWVLWFLPDEPSAAVQMLFTVNITAVLYYYIRSCRTDPGHVKATEEEKKKNIVVLAEAGCLDPRIFCTSCMMRKPMRANHCFSCNACVAKQDHHSIWINGCIGARNHPFFVLFLVALNFLCIWMFYGSITYWSRHCPLHYSEEGIWGALTALMGCSPWLLYVFCFVFFHTTWASILLVLQLYQIAFLGLTTSERANLMHRQRKLPQAVSLRQNPFNHGVVKNLVNFFQWRFCGLCKPMVLDWTQQHPMGLGRDMFSSPDAV
What is the function of this protein?
Putative palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.
What are the official names of this protein?
Putative palmitoyltransferase ZDHHC13, DHHC domain-containing protein 13, DHHC-13, Zinc finger DHHC domain-containing protein 13.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: GLOD4_CAEEL
Sequence: MTARALHYVFKVANRAKTIDFFTNVLNMKVLRHEEFEKGCEATCNGPYNGRWSKTMIGYGSEDEHFVLEITYNYPIHKYELGNDYRAIVIDSDQLFEKVEKINHRKSGCGRLAVKDPDGHEFKIGKADQSPKVLRVQVNVGDLEKSKKYWNETLGMPIVEEKSSRIRMSYGDGQCELEIVKSQDKIDRKTGFGRIAFSYPEDKLESLQDKIKSANGTIINELTTLETPGKADVQVVILADPDEHEICFVGDEGFRALSKIDDKAESELKEQIKKDDSEKWI
What is the function of this protein?
Thought to act as a glyoxalase.  May remove methylglyoxal from mitochondrial proteins.  Has roles in reducing oxidative stress and increasing lifespan.
What are the official names of this protein?
Glyoxalase 1, CeGly, Glyoxalase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: MUTS_RHIL3
Sequence: MNARIDTGNEAFSAAELATAESRASATPMMEQYIEIKANNPDSLLFYRMGDFYELFFEDALEASRALGITLTKRGQHMGQDIPMCGVPVHAADDYLQKLISLGFRVAVCEQIEDPAEAKKRGAKSVVRRDVVRLVTPGTITEEKLLSPSESNYLMALTRIRGSGEALLALAWIDISTGVFRLAETEASRLLADILRIDPRELILPDTIFHDPELKPVFDVLGRTAVPQPSVLFDSASAEGRIARYFGVATLDGFGTFSRAELAAAAAAVAYVEKTQIAERPPLGKPERESAASTLFIDPATRANLELARTLSGDRNGSLLKAIDRTVTGGGARLLAERLMSPLTDPARINARLDSIGFLIDEPLLCGNLRDTLKHVPDMPRALSRLALDRGGPRDLSAIRQGLDAAGGVAVMLGKAVLPEELGQALSELQALPATLEKLLAETLAEELPLLKRDGGFLRDGANAELDEVRALRDQSRRVIAGLQLQYAEETGIRSLKIKHNNVLGYFIEVTAGNASPMTETADAKARFIHRQTMANAMRFTTTELADLESRIANAADQALTIELEAFDRMTAAVVAEAEAIKSGARALAVIDVAAGLALLAEEQAYCRPQVDGSKMFAIESGRHPVVEQALRRQAGGPFVANHCDLSPKTGDRDGAIWLLTGPNMGGKSTFLRQNALISILAQMGSFVPATSAHIGIVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQASDRSLVILDEIGRGTATFDGLSIAWAAVEHLHEANRCRGLFATHFHELTVLSEKLGRLSNATMRVKEWDGDVIFLHEVGPGAADRSYGIQVARLAGLPASVVARARDVLTRLEDADRKNPASQLIDDLPLFQVAVRREETARGASKVEEALKAMSLDDMTPREAMDALYDLKKKLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PROB_VIBCH
Sequence: MTTNQRSIKAPQTVVVKLGTSVLTGGTLALDRAHMVELARQCAELKKQGHSVVIVTSGAIAAGREHLGYPALPNAISSKQLLAAVGQSRLIQVWESLFAIYGIKIGQMLLTRADLDDRERFLNARDTINALVENGIVPVVNENDAVATNEIKVGDNDNLSALVGILCGADKLLLLTDQKGLFTADPRKDPNAQLIKEVTTIDDTLRKIAGGSGTTLGTGGMATKLQAADIARRAGIEVIIAAGRAPNVIFDSLSDEPQGTRFLALEEALENRKRWILAGPAASGDIVIDDGAVKAVQTKGSSLLAKGVVRVQGQFARGEVVRVLDKQSHLIARGIAAYSNDELAQIAGKHSKEIIDILGYDHGSEVIHRDDMVVIQE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T170B_RAT
Sequence: MRAEGADHSMINLSVQQVLSLWAHGTVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVLSIIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL
What are the official names of this protein?
Transmembrane protein 170B, Liver regeneration-related protein LRRG102.
What is the protein family that this protein belongs to?
Belongs to the TMEM170 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSPC3_RICFE
Sequence: MNTYLSEITNLIYYINLKEVCMLYNNIKSYLLSGITVILLTGHPVIAADNVSKPDNKSQTAYLQHPPDLRPFSIFDYYLDNMFEHKLSAYSSSAIRTKFITQDKQYILVLEVPGYDKSQIKVKVNSNKLFITGNVEQNNKSEASDDYTKRNFNYVVSLYEDVDQNNISSNLKNGILTITLPRIEVKEKDAKEIPIQ
What are the official names of this protein?
Small heat shock protein C3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: T2A1_ANAVA
Sequence: MPYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQMRDIRPTLLAASGVSDKAAGHLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGDTLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNSKTWLNQPDDDTDIELRLRGLSWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPAGADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLTQPDQVASLCAWFIQL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CYCGRG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme AvaI, R.AvaI, Endonuclease AvaI, Type-2 restriction enzyme AvaI.
Protein: FIC_SALTY
Sequence: MSDKFGEGRDPYLYPGLNVMRNRLGIHQAQRLAQAAYEMTALRAATIELGPLVRGLPHLCAIHRQLYQDIFDWAGQLREVDIYQGDTRFCHFAYIEKEGNALMQDLEEEGYLVGLAHEKFVERLAHYYCEINVLHPFRFGSGLAQRIFFEQLALHAGYALSWQGIAVETWKQANQSGAMGDLSALRAIFQKAISEARETE
What is the function of this protein?
Involved in cell filamentation induced by cyclic AMP.
What are the official names of this protein?
Probable protein adenylyltransferase Fic, Cell filamentation protein Fic.
What is the protein family that this protein belongs to?
Belongs to the fic family.
Protein: XYLA_PARXL
Sequence: MSYFEHIPEIRYEGPQSDNPLAYRHYDKSKKVLGKTLEEHLRIAVCYWHTFVWPGVDIFGQGTFRRPWQQAGDAMERARQKADSAFEFFSKLGTPYYTFHDTDVSPEGSSLKEYSENFLRITDYLARKQEDTGIKLLWGTANLFSHPRYAAGAATSPDPEVFAFAATQVRHALDATQRLGGDNYVLWGGREGYDTLLNTDLMRERDQLARFLHMVVDHAHKIGFKGSLLIEPKPQEPTKHQYDYDVATVHGFLLQHGLEKEIRVNIEANHATLAGHSFHHEIATAYALGIFGSVDANRGDPQNGWDTDQFPNSVEELTLAFYEILKHGGFTTGGMNFDSKVRRQSVDPEDLFYGHIGAIDNLALAVERAAVLIENDRLDQFKRQRYAGWDADFGRKILSGDYSLSTLATDALARGLNPQHASGHQELMENIVNQAIYSGR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L_EBOZ5
Sequence: MATQHTQYPDARLSSPIVLDQCDLVTRACGLYSSYSLNPQLRNCKLPKHIYRLKYDVTVTKFLSDVPVATLPIDFIVPILLKALSGNGFCPVEPRCQQFLDEIIKYTMQDALFLKYYLKNVGAQEDCVDDHFQEKILSSIQGNEFLHQMFFWYDLAILTRRGRLNRGNSRSTWFVHDDLIDILGYGDYVFWKIPISMLPLNTQGIPHAAMDWYQASVFKEAVQGHTHIVSVSTADVLIMCKDLITCRFNTTLISKIAEIEDPVCSDYPNFKIVSMLYQSGDYLLSILGSDGYKIIKFLEPLCLAKIQLCSKYTERKGRFLTQMHLAVNHTLEEITEMRALKPSQAQKIREFHRTLIRLEMTPQQLCELFSIQKHWGHPVLHSETAIQKVKKHATVLKALRPIVIFETYCVFKYSIAKHYFDSQGSWYSVTSDRNLTPGLNSYIKRNQFPPLPMIKELLWEFYHLDHPPLFSTKIISDLSIFIKDRATAVERTCWDAVFEPNVLGYNPPHKFSTKRVPEQFLEQENFSIENVLSYAQKLEYLLPQYRNFSFSLKEKELNVGRTFGKLPYPTRNVQTLCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGEHATVRGSSFVTDLEKYNLAFRYEFTAPFIEYCNRCYGVKNVFNWMHYTIPQCYMHVSDYYNPPHNLTLENRDNPPEGPSSYRGHMGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVMGDNQCITVLSVFPLETDADEQEQSAEDNAARVAASLAKVTSACGIFLKPDETFVHSGFIYFGKKQYLNGVQLPQSLKTATRMAPLSDAIFDDLQGTLASIGTAFERSISETRHIFPCRITAAFHTFFSVRILQYHHLGFNKGFDLGQLTLGKPLDFGTISLALAVPQVLGGLSFLNPEKCFYRNLGDPVTSGLFQLKTYLRMIEMDDLFLPLIAKNPGNCTAIDFVLNPSGLNVPGSQDLTSFLRQIVRRTITLSAKNKLINTLFHASADFEDEMVCKWLLSSTPVMSRFAADIFSRTPSGKRLQILGYLEGTRTLLASRIINNNTETPVLDRLRKITLQRWSLWFSYLDHCDNILAEALTQITCTVDLAQILREYSWAHILEGRPLIGATLPCMIEQFKVFWLKPYEQCPQCSNAKQPGGKPFVSVAVKKHIVSAWPNASRLSWTIGDGIPYIGSRTEDKIGQPAIKPKCPSAALREAIELASRLTWVTQGSSNSDLLIKPFLEARVNLSVQEILQMTPSHYSGNIVHRYNDQYSPHSFMANRMSNSATRLIVSTNTLGEFSGGGQSARDSNIIFQNVINYAVALFDIKFRNTEATDIQYNRAHLHLTKCCTREVPAQYLTYTSTLDLDLTRYRENELIYDNNPLKGGLNCNISFDNPFFQGKQLNIIEDDLIRLPHLSGWELAKTIMQSIISDSNNSSTDPISSGETRSFTTHFLTYPKIGLLYSFGAFVSYYLGNTILRTKKLTLDNFLYYLTTQIHNLPHRSLRILKPTFKHASVMSRLMSIDPHFSIYIGGAAGDRGLSDAARLFLRTSISSFLTFVKEWIINRGTIVPLWIVYPLEGQNPTPVNNFLYQIVELLVHDSSRQQALKTTISDHVHPHDNLVYTCKSTASNFFHASLAYWRSRHRNSNRKYLARDSSTRSSTNNSDGHIERSQEQTTRDPHDGTERNLVLQMSHEIKRTTIPQENTHQGPSFQSFLSYSACGTANPKLNFDRSRHNVKSQDHNSASKREGHQIISHRLVLPFFTLSQGTRQLTSSNESQTQDEISKYLRQLRSVIDTTVYCRFTGIVSSMHYKLDEVLWEIESFKSAVTLAEGEGAGALLLIQKYQVKTLFFNTLATESSIESEIVSGMTTPRMLLPVMSKFHNDQIEIILNNSASQITDITNPTWFKDQRARLPKQVEVITMDAETTENINRSKLYEAVYKLILHHIDPSVLKAVVLKVFLSDTEGMLWLNDNLAPFFATGYLIKPITSSARSSEWYLCLTNFLSTTRKMPHQNHLSCKQVILTALQLQIQRSPYWLSHLTQYADCDLHLSYIRLGFPSLEKVLYHRYNLVDSKRGPLVSITQHLAHLRAEIRELTNDYNQQRQSRTQTYHFIRTAKGRITKLVNDYLKFFLIVQALKHNGTWQAEFKKLPELISVCNRFYHIRDCNCEERFLVQTLYLHRMQDSEVKLIERLTGLLSLFPDGLYRFD
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: GG12H_HUMAN
Sequence: MSWRGRSTYYWPRPRRYVQPPEMIGPMRPEQFSDEVEPATPEEGEPATQCQDPAAAQKGEDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC
What are the official names of this protein?
G antigen 12H, GAGE-12H.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: KCNE3_MOUSE
Sequence: METSNGTETWYMSLHAVLKALNTTLHSHLLCRPGPGPGPDNQTEDRRASLPGRNDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.  Associated with KCNC4/Kv3. 4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells.  Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 3, MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Perikaryon. Cell projection, dendrite. Membrane raft. Note=Colocalizes with KCNB1 at high- density somatodendritic clusters on the surface of hippocampal neurons.
Protein: MAND_DICDI
Sequence: MESSKFVKIIWVFGIWILVFTFLIIYNNYDYKSTFGINKFEKRSLKTINQINNKENGDDKKLSVFLIPHSHCDGGWLQDYDGYYYNIVQYILSGVVNELNLDKEKKFNWVEIGFFSRWWNDQNEIQKEIVRNLINNKQLSFISGGWVQNDEATATIDDVITQMTQGHQWLKDTLNYTVEYAWQIDPFGYSSSTPTIFSSMGIKGLVINRVSNDVKSYMKSVKEMEFIWKGSESLGEQSQMLVSTLNIHYDYPKHIDPKKDFSLNDRIKGFTKYLNDLSKTRESNILMIPLGDDFRYSNAKTEFSVSKEWVKALQDNKEYYNIKEIKYATLDEYFIALEDSFLRNNKFGKSRKQNVYTETFSDGDDEVSALSLYNKDFFPYSTGNLEYWTGYYTTRPLLKRLIRESSLLQKSSDILYTLAIGENSNNQIDINNLQTLSNQLNENRNTIALVQHHDIVTGTSRSFVLNDNFQRLQKSRISNYNIISNSLEYLLNKSNNKTNNNNNNNNKNNNNNNNNNNNNNNNLKNTNSISTTGSSSSSGSGSSNNNNNTVNKSEPFNFENAIDLSNESNNQYSLVFHNTLGWEVNQHVSFRIKVNKNDNQLLESIQLVEAISNKTIQIQIIPIQDDSNCQSIENNYIVFAIINLPPLGLNTYYLSIANSEDSKSNFTYLSKPKLLKKGNEINFNNNRFKVEFESNGLISKITDKNSNEIKTIEQTFHQYSTKKSGPYIFNVKGGKKHGFLENPDKFIYHDGPLVSQLTMLYGVDDYCNVTSIVVQRIYKNNNEINNSNSKSLITENYIETGYSINGDMNRETTINYKVKDLENDDIFYTDNGLESRKRIYNHDRSVNQNYYPVLGYIKLKETSENNNHQYTVYVDRSVGATSPSDGEMEIMIHRTMDTDDWKGVNWPSKDIGRSDAKLYFNMDLVNNQLQNEKRISLHITNQPIMFVKKHNNQTGYLLKYSPLSNQLPSNIHLQSLLTLKNNTVGLRLFNIHEVDSNTQSTTDTDKSTLFNELEISNFIETGLSFLKLTKNNLIDKFSTRINKKFPIKCGESEYSFINEKPSSIIFSNNGTNNIIDGENKGENNKTIETIQIKPHEIKSFTFNFNFQLDQIIPNNNNNNNKYAINKELNNEYIEQSIENQRYEYDFSFFPIKPTFYDDRGKYNRPNHLALILSLSIGIPAGILIIVIALVVTYKKRKNRKTLTSSNSSSNLIQQEDQTDYSP
What are the official names of this protein?
Alpha-mannosidase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UNG_LACLS
Sequence: MKKTDWSQPLRNRLAEDYFPKMIEFINQTYQEGKIYPPENQIFRAIELTPLAQTKVIIVGQDPYPQPGKAQGLAFSYPATFKVNRPDSIVNIQKELREEGFSKEDSDLTAWAEQGVLLLNAVLTVPEFASNAHAGKIWEPLTDEIIKIASDDERPKVFILWGGFARKKAKLIDGSKHLILEAAHPSPLSASRGFFGSHPFSKTNDFLVQTGQSPIDWSK
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY1R_XENLA
Sequence: MNFSTYFENLSVPNNISGNITFPISEDCALPLPMIFTLALAYGAVIILGLSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLATIMCLPFTLIYTLMDHWIFGEVMCKLNEYIQCVSVTVSIFSLVLIAIERHQLIINPRGWRPNNRHACFGITVIWGFAMACSTPLMMYSVLTDEPFKNISLDSYIGKYVCLEDFPEDKFRLSYTTLLFILQYLGPLCFIFVCYTKIFLRLKRRNNMMDKIRDNKYRSSETKRINIMLLSIVVGFALCWLPFFIFNLVFDWNHEAVATCNHNLLFLICHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSREDDYETIAMSTMHTDVSKTSLKQASPIA
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Neuropeptide Y receptor type 1, NPY1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADS2_BOVIN
Sequence: MGKGGNQDEGATELEAPMPTFRWEEIQKHNLRTDKWLVIDRKVYNITKWSSRHPGGQRVIGHYAGEDATDAFLAFHRNLDFVRKFMKPLLIGELAPEEPSQDRGKNSQITEDFRALRKTAEDMNLFKSNQLFFLLHLAHIIAMESIAWFTLFYFGNGWIPTIITAFVLATSQAQAGWLQHDYGHLSVYKKSMWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPLYFQYQIIMTMIVRKYWADLAWAISYYTRFFITYIPFYGVLGSILFLNFIRFLESHWFVWVTQMNHIVMEIDREPYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVRSLCAKHGIEYQEKPLLRALQDIIGSLRKSGQLWLDAYLHK
What is the function of this protein?
Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain.  Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (By similarity).  Subsequently, in the biosynthetic pathway of HUFA n-3 series, it desaturates tetracosapentaenoate (24:5n-3) to tetracosahexaenoate (24:6n-3), which is then converted to docosahexaenoate (DHA)(22:6n-3), an important lipid for nervous system function (By similarity).  It can also desaturate (11E)-octadecenoate (trans-vaccenoate, a metabolite in the biohydrogenation pathway of LA and the predominant trans fatty acid in cow milk) at carbon 6 generating (6Z,11E)-octadecadienoate (By similarity).  In addition to Delta-6 activity, this enzyme exhibits Delta-8 activity with slight biases toward n-3 fatty acyl-CoA substrates (By similarity).
What are the official names of this protein?
Acyl-CoA 6-desaturase, Delta(6) fatty acid desaturase, D6D, Delta(6) desaturase, Delta-6 desaturase, Fatty acid desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS17_ECODH
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NHAB_ENT38
Sequence: MEISYGRALWRNFLGQSPDWYKLTLLAFLIINPLVFIFQPFMAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVVIGMTSAERVKDELATNLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKTVLSLSFCLAAAFLSAFLDALTVVAVVISVAIGFYGIYHRVASSSSDNDLQDDSQLDVNKRDVLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWNFTEFFLRVAPVSVPVFICGMLTCFLLERTKTFGYGVQLPGAVRDVLHEFDLKSRSQRTRQEKLALIAQGIIGAWLIFALAFHLAEVGLIGLSVIILATSFTGVTDEHAIGKAFTEALPFTALLAVFFAIVAVIIDQQLFTPIIHFVLQASPDSQLSLFYLFNGLLSSISDNVFVGSVYINEAKTALESGAIGINQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTVVLTLVGLLCVKFTLIPYTQWLMQIGILAAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_PSEF5
Sequence: MLTIRLALGGSKKRPFYHLTVTDSRNPRDGSHKEQVGFFNPIARGQEVRLSVNQERVAYWLSVGAQPSERVAQLLKESAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL13_HELPY
Sequence: MTKTAKVNDIVRDWVVLDAKDKVFGRLITEIAVLLRGKHRPFYTPNVDCGDFVVVINANKVKFSGMKLEDKEYFTHSGYFGSTKSKTLQEMLEKAPEKLYHLAVRGMLPKTKLGKAMIKKLKVYRDDKHPHTAQTSKKDAK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.