PharMolix/UniProtQA huggingface dataset:
Protein: MAF_RAT
Sequence: MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPASGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGGAPHYHHHHHHATGHHHHPTAGAPGAAGSASASASGAGGAGGGGPASAGGGGGGGGGGTAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENCSSSDNPSSPEFFM
What is the function of this protein?
Acts as a transcriptional activator or repressor.  When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription.  Involved either as an oncogene or as a tumor suppressor, depending on the cell context.  Binds to the ARE sites of detoxifying enzyme gene promoters.  Involved in embryonic lens fiber cell development.  Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation.  Activates the expression of IL4 in T-helper 2 (Th2) cells.  Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression.  Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.  Activates transcription of the CD13 proximal promoter in endothelial cells.  Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction.  Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development.  Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter.  Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters.  Binds element G1 on the glucagon promoter.  Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells.  It may interact with additional basic-zipper proteins that determine a subtype of Maf-responsive element binding (By similarity).
What are the official names of this protein?
Transcription factor Maf, Proto-oncogene c-Maf, Transcription factor Maf-2, V-maf musculoaponeurotic fibrosarcoma oncogene homolog.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HDRC1_METJA
Sequence: MVIYAQKDISNDFIKEIIKTGEILGEGHVSSFKACYQCGTCTGSCPSGRITAFRTRKLIRYAQFGMKSAIIDSEDLWMCTTCYECYERCPRTVKITDIIKVLRNIAAREGKMAEAHKKTALYVFKTGHAVPINDQIKKARKEIGLTEIPPTTHKYPDALEVVRGIMKDLRFCDMVGICTETMQLKPVEWKDMSE
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
What are the official names of this protein?
CoB--CoM heterodisulfide reductase iron-sulfur subunit C 1.
What is the protein family that this protein belongs to?
Belongs to the HdrC family.
Protein: EFCB5_MOUSE
Sequence: MLMQVEKKKLLSQADIPTKFDPINYLGEYLMRHNTHYIKDPGVSGYQRVMKEITEELKTHVPDTINNRISKMKEKVKEKREQREYISTVKVKVAGMRKQALEEQFNEWVLNPKGMIPIVVYISSYITDLKSEVFEEFLKHLCHSAEEFREIILTDMRRQMFAELFLQCDSGKVMALDRQRTLALLEAFYDQCSSTTRSLLRNPRQWPFVEFEEIELIEFWGDMDIKKHIYEDFDALLLKMNMLVAEKLAGKLAENKDLPQQQRDQELSSDSTTEPETATQLTSQQRSRRVSLTGQGQGKGPRKTSASKQGASRGSVAEQGSRRSSGVNQTQQRGSVAEQGSRRSSAVEQTQQRGSVAEQGSRRSSTVEQTRQRGSVAEQGSRRSSTVEQTQRRGSVAEQGSRRSSGVNQTQQRGSVAEQGSRRSSAVEQTQQRGSVAEQGSRRSSAMEQEPQTAQDPNSDSLPEQESHRGSITEGSHRGSISEPGQRRASVTGQRRKSSVDDSGSAGSRRGSGTDQGQHRGSVGQRKGSGERKMSASEYGPHQESITEEPLTASEPGPQIDTIQELDEDSTPQLEDDSALKESKTSELTKIETQEEKPLLLINEEQVPRDSKQPEVPTSSKKERPSGSPKKGRLSGTSKRDSQKDKACEPKPQHVEGKKWSGEFLICDWKIKHVKSEEEEQAKLICDDTRFTDLHATIRNFQTYKGIKGRSAFNGVSLDLLQFVQLLETFVGEDTSFSLSKDLASFFQKNYSETKQEKIKALEQARQNSSRIRRRILLQAIFEKWDNDGSGFLDLNEVDDLLYTYKEGMERESMKKAKLHINFPEPSPGHEVKLSSKQFQRYIELVVSELRGNEDEVLESVVEFLMGSLERSHVEGLRNCARRKWLHQIQYAAETSGVSLEPVYTETFRVLTQDAEAHGNKKISAHISLLEENVFLPERGHVLLRNVACTLDDAPFVLNKVLYRDMKGISFTVVDEGKPIHVPQVQHHGNIFFWNSFRSKNEYNGSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIKFYQGVANAFSTAYHHVHSREHVLHSVMTGIRWLFSVTSGITTITTCFIEPSSEQEDYVLRNMMVTDCLGLAEIHTDPPTITRNACIFRDFLFKCTDTSEVILASSGGETHIAIPLRQRTKEAMGILDVNIGRSRMLLYQEYKDLQKMVKMIQNVSYEILGEFSGEIEKTMVIEMESAGEVKRAGILFFRTMLQELQECLCLLDSMDFVSLLLYEHKYHVDSILQDITLQEVEANVALVHDVLKGVILFSQREKDSLSDLEEWEKWKFHINKYLVEEICVLDPTASNVEVNVELVTSYIQAHSRTEVWNFRNIVIELLYHWINICLTLIELNMRQDVSIIPPLPKKSATSIYAISSERSIREKL
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 5.
Protein: YQHL_BACSU
Sequence: MSNMIVLIIFAAFIIYMIASYVYQQRIMKTLTEEEFRAGYRKAQLIDVREPNEFEGGHILGARNIPLSQLKQRKNEIRTDKPVYLYCQNSVRSGRAAQTLRKNGCTEIYNLKGGFKKWGGKIKAKK
What are the official names of this protein?
Uncharacterized protein YqhL.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COAE_LISIN
Sequence: MGKTIGLTGSVATGKSTVSNLIQQAGIPLVDADIAARKVVEKGTDGLAEIVAYFGKDILLEDGTLNRAKLGEIIFQDKEKREKLNEITHPRVKDYMLNERERFFEAGEKVVFFDIPLLFESHLESLVDQIIVVWTTPETELKRLMERNNLTKEEALARINSQMGIDEKAKKADFVIDNNESLEKTQKQVLTFIERFVNNK
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL5AP_SHEEP
Sequence: MDQETVGNIVLLAIVTLISVVQNGFFAHKVEHESKTHNGRSFQRTGPLAFERVYTANQNCVDAYPTFLVMLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFAMSLAGILNYFLIAFFGSDFENYIKTVTTT
What is the function of this protein?
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase).  Anchors ALOX5 to the membrane.  Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5.  Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).
What are the official names of this protein?
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CALM_HALOK
Sequence: MTDALSEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKETDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVAMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: HOX3_ORYSJ
Sequence: MMGATSPSGLELTMAVPGLSSSGSEGAGCNNNNAGGGCNMRDLDINQPASGGEEEEFPMGSVEEDEEERGVGGPHRPKKLRLSKEQSRLLEESFRLNHTLTPKQKEALAIKLKLRPRQVEVWFQNRRARTKLKQTEMECEYLKRCFGSLTEENRRLQREVEELRAMRVAPPTVLSPHTRQPLPASALTMCPRCERITAATGPPAVRPPPSSAAAAAPSPFHPRRPSAAF
What is the function of this protein?
Probable transcription repressor that binds to the DNA sequence 5'-CAAT[GC]ATTG-3'.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX3, HD-ZIP protein HOX3, Homeodomain transcription factor HOX3, OsHox3.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_OENOB
Sequence: MDLSTLKPVAGSRKSSTRKARGFSAGKGKTAGRGQKGQKAREGKKLRLSFEGGQMPLMRRMPKRGFNNISRKEYAIVNLDQLNKFDDGTTVSASSLKEAGIIKKELSGVKVLASGKLNKKITIHAAKASQAAQDSIKEAGSKIILTTETADSEN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: P2C69_ARATH
Sequence: MGYLDLALSYSNQPQTVEAPASGGGLSQNGKFSYGYASSAGKRSSMEDFFETRIDGINGEIVGLFGVFDGHGGARAAEYVKRHLFSNLITHPKFISDTKSAITDAYNHTDSELLKSENSHNRDAGSTASTAILVGDRLVVANVGDSRAVISRGGKAIAVSRDHKPDQSDERERIENAGGFVMWAGTWRVGGVLAVSRAFGDRLLKQYVVADPEIQEEKIDDTLEFLILASDGLWDVFSNEAAVAMVKEVEDPEDSAKKLVGEAIKRGSADNITCVVVRFLEKKSASSSHISSSSSKEAKEMPPLGDLAISSNEAKQVQIGSGNKPENVTNRKPDTASRSTDTLTLERNSVTDKV
What are the official names of this protein?
Probable protein phosphatase 2C 69, AtPP2C69.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: SYS_ACAM1
Sequence: MIDLKQLRENPEAFAECLSRRGDYDLQAILDLDQKQRELETERSQLQARSNQIGKTIGERMKGGANPKDPEIQNLRQEGSTVKATLSDLEPKERDLKAEIGELLLTIPNLPSDDTPVGKDETANVEVSRWGDEYIPKNAKLAHWEIGENLGILNFERSVKVAQSRFATLVGAGAALERALIQFMLDQQVEAGYVEVLPPVLVNSDSLTATGQLPKFAEESFKCAEDDLWLSPTAEVPVTNLYRDEIINADDLPIFHCAYTPCFRREAGSYGRDTRGLIRLHQFNKVELVKLVHPSTSAAEHEALVKNAAAILEALKLPYRVLQLCTGDLGFSAAKCYDLEVWLPSADCYREISSCSNFLDFQARRGNIRFKESGQKGTQFVHTLNGSGLAVGRTMAAVLENYQQPDGSVQVPDVLQPYLKRKVL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIN1_SCHPO
Sequence: MSNTGLPKPWIVKISRSRNRPYFFNTETHESLWEPPAATDMAALKKFIANELQESVTPTEASNSPKIRASHLLVKHRESRRPSSWKEEHITRSKEEARKLAEHYEQLLKSGSVSMHDLAMKESDCSSARRGGELGEFGRDEMQKPFEDAAFALKPGEISGVVETSSGFHIIQRHA
What is the function of this protein?
Has a role in the G1/S stage transition of mitosis where it is involved in the dephosphorylation of cdc25 and wee1.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase pin1, PPIase pin1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPH_SYNS3
Sequence: MDTHAFKRSLHHSDRYNRRGFGRADEVAGSLEQAYQSSLIGSIRDNGYSLTHGRLKVRLAEAFGFCWGVERAVAMAYETRRHYPQERIWITNEIIHNPSVNDHLREMDVLFISVEGGVKDFSGVATGDVVILPAFGATVQEMQLLNERGCHIVDTTCPWVSKVWTTVEKHKKQSFTSIIHGKVKHEETLATSSFAGTYLVVLDLEEARLVADYILGKGNRESFMERFSKACSPGFDPDRDLEHLGVANQTTMLKSETEEIGRLFERTMLSKYGPTDLNEHFLAFNTICDATQERQDAMFSLVDETVDLMVVIGGYNSSNTTHLQEIAVSRGIRSFHIDTPERIHTDNSIEHKPLGEELTVEELFLPSGPVTVGITSGASTPDRVVEHVIQRLIALSEN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ADCY1_BOVIN
Sequence: MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGIFVRILAERAQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERERKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPVLPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGAGAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPFGRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA
What is the function of this protein?
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:2472670, PubMed:2022671, PubMed:19029295).  Mediates responses to increased cellular Ca(2+)/calmodulin levels (PubMed:2022671, PubMed:19029295).  May be involved in regulatory processes in the central nervous system.  May play a role in memory and learning.  Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).
What are the official names of this protein?
Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, AC1, Ca(2+)/calmodulin-activated adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft. Note=Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia.
Protein: ALX_SHIFL
Sequence: MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAWSLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFSYFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMALAHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVIFAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRG
What is the function of this protein?
Has been proposed to be a redox modulator.
What are the official names of this protein?
Putative membrane-bound redox modulator Alx.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATR_ECOLI
Sequence: MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTDPTHVIWTQA
What is the function of this protein?
Repressor of the gat operon for galacticol transport and metabolism.  In K12 strains the operon is constitutively expressed because this gene is inactive (PubMed:7772602).
What are the official names of this protein?
Putative galactitol utilization operon repressor.
Protein: D103A_HUMAN
Sequence: MRIHYLLFALLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
What is the function of this protein?
Exhibits antimicrobial activity against Gram-positive bacteria S. aureus and S. pyogenes, Gram-negative bacteria P. aeruginosa and E. coli and the yeast C. albicans.  Kills multiresistant S. aureus and vancomycin-resistant E. faecium.  No significant hemolytic activity was observed.
What are the official names of this protein?
Beta-defensin 103, Beta-defensin 3, BD-3, DEFB-3, HBD3, hBD-3, Defensin, beta 103, Defensin-like protein.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBB_ORYSJ
Sequence: MASVAELKEKHAAATASVNSLRERLRQRRQMLLDTDVERYSRTQGRTPVSFNPTDLVCCRTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNGQSVACGGLDSACSIFNLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLSINSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTGHQLQVYSREPDRNDNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHEGRISCLGLSSDGSALCTGSWDKNLKIWAFSGHRKIV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta, WD40 repeat-containing protein 80, OsWD40-80.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: FABZ_CLOB1
Sequence: MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NREB_STAES
Sequence: MLEQTDLSLEQLLKNYYETTNEKIVFVNRQGKIIAMNDAAKDILTEEDNYNAMTNAICHRCEGYSNEYDVQSCKDCFLETTQLQHSNFQVFMKTKDNEIKPFTAMYQNIDEQRGISAFTLQNVAPQIERQEKMYQQKMLHRSIQAQENERKRISRELHDSVIQDMLNIDVELRLLKYKHRDKVLAETSQRIEGLLSQLIDDIRNMSVELRPSSLDDLGIEAAFKSYFKQFEENYGMHIKYDSNIKGMRFDNEIETVVYRVVQEGVFNALKYAEVNEIEVSTHSDGKQLVAEVVDRGKGFSLDHHPKGSGLGLYGMRERAELVNGHVNIETHINRGTIITLDIPI
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC.  NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity).
What are the official names of this protein?
Oxygen sensor histidine kinase NreB, Nitrogen regulation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_BURPS
Sequence: MNTTKPSPATAAELLRASPLDALDARILLAHALGWSRTQLITRADEPLDAAARARYLALQARRAAGEPIAQLTGAREFFGLEFDITPDVLIPRPETELLVETALDAIDGIASPCVLDLGTGSGAIAVSIASERPDARVWALERSVAALDVARRNARKLLDPARAGGPLRFLESDWYAALDPGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDENDGLAAIRTIVAGAHAFVAPGGALWLEHGYDQAAAVRTLLDAAGFADVESRADLASIERASGGRLPG
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: HIS1_CYAP4
Sequence: MLTVALPKGALLKESIRLFQAIGLDFSGFLDPANRQLQIVAPTGNAQALLVRTQDVPVYVEYGQAQLGIVGYDVLREKNPQVAHLLDLQFGRCRLSVAVKQASPYRCSLDLPPHSRVASKFVHCARAYFEQMDLPVEVVPLYGSVELGPLTGMSEAIVDLVSTGRTLKENGLVELEVLFESTARLIAHPLSYRLNRFGLHQPIEQIQALLSSPVP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_HAES1
Sequence: MAREFKRSDRVAQEIQKEVAVILQREVKDPRIGMVTVSDVEISSDLAYAKIFVTFLFDQDENVIEQGMKGLEKASPYIRSLLGKVMRLRIVPELRFIYDQSLVDGMRMSNLVTNVVREDEKRHVEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_PSYIN
Sequence: MTLLISNDDGVYAPGLNALYHALKDLADVKVVAPDRNHSGASNALTLENPLRLQYLDNGFIAVSGTPTDCVHLALNKICITVPKLVVSGINHGANMGDDVLYSGTVAAAMEGRFLGLPAIAISLAGQTHFESAAFYAKQLVGKLLASPLSTDQVLNVNVPDLPLAQIKGIKITRLGKRHKAEMIEKSVDPRGKEIFWVGPPGKIAEAGDGTDFHAIENGYVSITPLKIDLTATEQLSDLTKWLDK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN_BACPU
Sequence: MKKISSVFTMFALIAAILFSGFIPQQAYAETTLTPTATNKTASIQLTSDVHTLAVINTFDGVADYLIRYKRLPDNYITKSQASALGWVASKGNLAEVAPGKSIGGDVFSNREGRLPSASGRTWREADINYVSGFRNADRLVYSSDWLIYKTTDHYATFTRIR
What is the function of this protein?
This is a purine-specific ribonuclease.
What are the official names of this protein?
Ribonuclease, RNase Bp.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPGP_MYCTU
Sequence: MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWGGADEPDRPVVLVAHGGLIAALSAALLKLPVANWPALGGMGNASWTQLSGHWAPGSDFESIRWRLDVWNASAQVSSDVL
What is the function of this protein?
Involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharides (MGLPs).  Catalyzes the dephosphorylation of glucosyl-3-phosphoglycerate (GPG) to glucosylglycerate (GG).  GPG is the preferred substrate, but GpgP also exhibits low dephosphorylation activity on mannosyl-3-phosphoglycerate (MPG) and mannosylglucosyl-3-phosphoglycerate (MGPG) in vitro.  Shows only trace of phosphoglycerate mutase (PGM) activity.
What are the official names of this protein?
Glucosyl-3-phosphoglycerate phosphatase, Mannosyl-3-phosphoglycerate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: PROA_PROM5
Sequence: MTDIFEVPSPDNNLLDKAEQLRLASIKTSQTNNNERIRALNLMADSLEKNSKEIIDSNFEDYKKAEIKGISKALLSRLKLSKEKLNLGIEGIRKVGDLSDPLGQIQIKKELSKGLILERKTVPIGVLGVIFESRPDAVMQISSLAIRAGNGVMLKGGSEANFTNQAIVSALKKGLQKSNIDDNAICLLTSRKDSMAMLNLEKFINLIIPRGSNELVKFIQENTGIPVLGHADGICHLYIDDEVNLDIALKVALDSKIQYPAACNAIETLLIHKSIAPAFLKKAIPIFNSNNVKLIGDKKAVKLGVAFEANYEDWQTEYLDLILSIKIVDDLEEGIAHIQKFSSKHTDGIITENISNANKFMSEIDSAGVFHNCSTRFADGFRYGFGAEVGISTQTLPPRGPVGLEGLVTYKYFLRGEGHSVDDFSSGKSIYTHKDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.