PharMolix/UniProtQA huggingface dataset:
Protein: RPIA_DINSH
Sequence: MSGEMSPIDRAKYVAAKRAVGFVEDGMRVGLGTGSTAAWMVRHLAETVDQEGMDITCVATSTRTAELARDLKLHVTTLDEVKWLDLTIDGADEFDPTLNLIKGGGGALLQEKIVATASDRMIVITDASKAVATLGAFPLPVEVIRFGWETTRTLIEETLVNVDVGGREAILRMENGMPYVTDEGNFIVDLHLERIGNPRQVSLVLNQLPGVVENGLFLDICDVVVIGKSDGSVELRDINEGSVHQEQVEVTATGNVFSDL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYG_BACAN
Sequence: MYSMEQVVNLAKHRGFVFPGSEIYGGLANTWDYGPLGIELKNNVKKAWWKKFIQESPYNVGLDAAILMNPKTWIASGHVGNFNDPMIDCKKCKARHRADKLIEDALDAKGIEMVVDGLTFDQMADLMKEHEVKCPDCGSEEFTEIRQFNLMFKTFQGVTESSTNEIFLRPETAQGIFVNFKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPGEDLEWFAFWRETCKNWLLSLGMTEESMRLRDHGEEELSHYSNATTDIEFKFPFGWGELWGVASRTDFDLKRHMEHSNEDFNYIDPQTNERYVPYCIEPSLGADRVTLAFLCDAYEEEQLENDSRTVLRFHPALAPYKAAILPLSKKLSEGATEVFAELAKDFMVDFDETGSIGKRYRRQDEIGTPFCITYDFDSVEDKAVTVRDRDTMEQVRMPISELKGFLEKKIQF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I81A2
Sequence: MKTTIILILLTHWVYSQNPTSGNNTATLCLGHHAVANGTLVKTITDDQIEVTNATELVQSTSIGKICNNPYRVLDGRNCTLIDAMLGDPHCDVFQYENWDLFIERSSAFSNCYPYDIPDYASLRSIVASSGTLEFTAEGFTWTGVTQNGGSGACRRGSADSFFSRLNWLTKSGNSYPTLNVTMPNNNNFDKLYIWGIHHPSTNNEQTKLYIQESGRVTVSTKRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDILMINSNGNLVAPRGYFKMRTGKSSVMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKVTYGKCPKYIKQNTLKLATGMRNVPEKQIRGIFGAIAGFIENGWEGMVDGWYGFRYQNSEGTGQAADLKSTQAAIDQINGKLNRVIERTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDAEMNKLFEKTRRQLRENAEDMGGGCFKIYHKCDNACIGSIRNGTYDHYIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLICVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: IRF5_HUMAN
Sequence: MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
What is the function of this protein?
Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:11303025, PubMed:15695821, PubMed:22412986, PubMed:25326418, PubMed:32433612).  Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters (By similarity).  Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway (By similarity).  Key transcription factor regulating the IFN response during SARS-CoV-2 infection (PubMed:33440148).
What are the official names of this protein?
Interferon regulatory factor 5, IRF-5.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm: upon activation by the TLR adapter MYD88 and subsequent phosphorylation, translocates to the nucleus.
Protein: RL9_CALS8
Sequence: MKVVLLQDVKGLGKKDSIVEVNDGYARNYLIPRKLAAPLTEGLEKHIKEKKEAEQKKKEKELMLAKDLADKLEKSQVIIKAKAGENGKLFGSITNKEIADEIKRQLGIDMDKKKIELEDPIKQIGSYEVSIRLYQGIVAKLKVHVTSS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS5_NATTJ
Sequence: MRRKDFDPNKLDLSEKVVEINRVTKVVKGGRRFSFSALVVVGDENGYVGAGNGKAVEVPEAIRKGIEDAKKNLIKVPMVGTTIPHEIVGRDGGGQVLLKPAYEGTGVIAGGPVRAVLEQAGIRDILTKSLGSNNAKSMVNATIAGLNQLKTAEQVARLRGISVKDLQG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MYH10_BOVIN
Sequence: MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKIQVAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKSHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQAQLTDTKKKVDDDLGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLDHQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALEAREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHIEGASLELSDDDTESKTSDINETQPPQSE
What is the function of this protein?
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.  Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.  During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9 (By similarity).
What are the official names of this protein?
Myosin-10, Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, Non-muscle myosin heavy chain B, NMMHC-B, Non-muscle myosin heavy chain IIb, NMMHC II-b, NMMHC-IIB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Note=Colocalizes with MCC at the leading edge of migrating cells.
Protein: IMPA1_DICDI
Sequence: MENITLDQYLQSAVDVVKEIGPMILKNYNSRSKQIEYKGAIDLVTDTDKAVEEHIIKTLTTKYPHTKILGEESTKDGIYNWGNEPTWVIDPIDGTTNFVHRFPLFCVSIALSINKEIVVACLYAPVLDELFTATKGGGAFLNGESISVSSVEHLSQSIISTNVGYDRSDKGIEFMLTNFKNILKDNVQALRFSGTAAWEMASVSCGRVDSFYEWGIHPWDIAAASLLITEAGGVVVDPSGGKCDMESRKVLCGNPNIVNKLSKLLIEKPTSN
What is the function of this protein?
Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides.  Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
What are the official names of this protein?
Inositol monophosphatase, IMP, IMPase, D-galactose 1-phosphate phosphatase, Inositol-1(or 4)-monophosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APBC_RICTY
Sequence: MANLHQQQIIDKIQNITFKDGTFLNEVISDIIIKGNNIGFSIDISGKNKLEAEEIRLKAINELNNIKDVNNITIVFTQKKTIDKKAQKPKHFVENVKKIILVASGKGGVGKSTISALIAQQLSLENYQVGIVDADIYGPSIPHIFGINEIPKTVEGRIIPILAQNIQIISIGFFVKAHSAIIYRGPMASKIIYQLLSNTRWNNLDYLIIDMPPGTGDIHLSMLENYHLDGVIVVTTPQKISEIDVIRSIDLYRKLGLPILGIIENMIYMLESDRCGHLSKKYNIPLIAKIPIIPQIANACDKSLPLTNLLTLPLEKYL
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: YGFZ_SALSV
Sequence: MAFISFPPRHPSSSARLPLTLIALDDWALSSITGVDSEKYIQGQVTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVREAQLTELKKYAVFSKVVIAPDDERVLLGVAGFQARAALANVFSELPNSENQVVRDGASTLLWFEHPAERFLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRTGAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_BORPE
Sequence: MIFTGTANTRLAVDVVNHLDMSLGKMTVGRYSDGEVMVEINENVRGKDVFVLQPTCAPTNDNLMEIMVMVDALRRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLQVAGVDRVLTMDLHADQIQGFFDIPVDNIYAGPILLGDIWRRNFSNLVVVSPDIGGVVRARALAKQLEADLAIIDKRRPRANVSEVMNIIGEVDGRTCIIMDDMVDTAGTLCKAAQALKDRGAGAVYAYCTHPVLSGGAIERIETSSLDELVVTDTIPLSEQAQACGKIRQLSCAALLGETILRISNAESVSSLFAD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1R8_HUMAN
Sequence: MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
What is the function of this protein?
Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions.  It generates 5'-phosphate termini at the site of cleavage.  This isoform does not inhibit PP-1.  May be implicated in mRNA splicing.
What are the official names of this protein?
Nuclear inhibitor of protein phosphatase 1, NIPP-1, Protein phosphatase 1 regulatory inhibitor subunit 8.
Protein: SYV_BACFR
Sequence: MELASKYNPADVEGKWYQYWLDHKLFSSKPDGREPYTIVIPPPNVTGVLHMGHMLNNTIQDILVRRARMEGKNACWVPGTDHASIATEAKVVNKLAAQGIKKTDLSRDEFLKHAWAWTDEHGGIILKQLRKLGASCDWDRTAFTMDEKRSESVLKVFVDLYNKGLIYRGVRMVNWDPKALTALSDEEVIYKEEHGKLFYLRYKIEGEDGYAVVATTRPETIMGDTAMCINPNDPKNQHLKGKKVIVPLVGRVIPVIEDDYVDIEFGTGCLKVTPAHDVNDYMLGEKYNLPSIDIFNDNGTISEAAGMYIGMDRFDVRKQIEKDLEAAGLLEKTEAYTNKVGYSERTNVVIEPKLSMQWFLKMEHLAQIALEPVMKDDIKFYPAKYKNTYRHWMENIKDWCISRQLWWGHRIPAYFLPEGGYVVAVTDEEALKLAREKTGNPNLKMTDLRQDEDCLDTWFSSWLWPISLFDGINNPGNEEINYYYPTSDLVTGPDIIFFWVARMIMAGYEYEGKMPFKNVYFTGIVRDKLGRKMSKSLGNSPDPLELIEKYGADGVRMGMMLSAPAGNDILFDDALCEQGRNFCNKIWNAFRLVKGWENGMGTIDIPADAHLAVQWFDQRLDAAAVEVADLFSKYRLSEALMLIYKLFWDEFSSWLLEIVKPAYGQPVNGFIYSMTLSAFERLLAMLHPFMPFITEELWQQLREREPGASLMVQPLGEPGEVNEEFLQQFETAKEIISSVRTIRLQKNIALKEPLELQVVGANPVEKMNPVIRKMCNLSAIEVVDAKADGASSFMIGTTEFAVPLGNMIDVDAEIARMEAELKHKEGFLQGVLKKLSNEKFVNNAPAAVIEMERKKQADAESIIQSLKESIASLKNV
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF24_ANTSP
Sequence: SATFSHGSFCYIPPDTHCPLELSTYFRINNKESGQFERTLIIADKNSYVSYLEGCTAPQFDNNQLHAAVVELVALENATIKYSTVQNWYAGNEKGQGGIYNFVTKRGICIGNNSKILWTQVETGSAITWKYPSCILAGHNSIGEFSSIALTNNYQQADTGSKMIHIGKNTKSRILSKGISAGYSANSYRGLVKIGPKAHYSRNYSQCDSLLLSNTSKANTFPYIQAQNPYTKIEHEASTSKIGEEQIFYFLQRGINLENAISLMISGFCKEVLNELPMEFAVEADRLLNLKLEGTVG
What are the official names of this protein?
UPF0051 protein in atpA 3'region, ORF 3.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECA_STAAS
Sequence: MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSVTLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVEETEDAPKSLFDEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T1M2_METJA
Sequence: MKLRNVEPRFLKAYNILMDKFGLFPFTYDMAEKVLKDNYENVNEVLSKLADAGLLEKTAKKEDKRKKIYKIKPLTTEKIEKVSKDKLIGLLKQGADLIRTQVDYKVLLLFLFFKAISDKYLLKVEELKKEFEDLDEEDIYVLANEEILELYDVEGKKLYVWHEVANNPEDFINALNKIVEMNKEKLSGLDELIKRTGLPTLFENENRHIVQHLINLFSRADFSEASYDILGDAYEWTLNYFAPTKAKEGEVYTPIEVSKLIAHLVEPKDDEVILDPACGSGSMLIEQYRFAGSNPNIVLVGQERNDVTAVLAKLNFILHGINLKDAKVFIGDSLLNPKFESFIXEVKGTGKADKVVANPPWNQDGYDENTLKVNEKYKDIYMYGFPNKNSADWAWVQLINYYTEKKAGIVLDSGALFRGGKEKTIRKRFVDDDLIEAVVLLPEKLFYNCPAPGIILILNKNKPEERKGKILFINASNEYIKHPEVKKLNKLSDENIEKIAKAYKEFKDVDGFCKVVDIEEIRKNDYNLNVSLYISPIEEDEDVDLGEVYEELNKLHNEYLEKFEVVKGYLEEINGLIK
What is the function of this protein?
The subtype gamma methyltransferase (M) subunit of a type I restriction enzyme.  The M and S subunits together form a methyltransferase (MTase) that methylates A-2 on the top and A-3 on the bottom strand of the sequence 5'-GAYN(5)GTAA-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Type I restriction enzyme MjaVIII methylase subunit, M protein, Type I methyltransferase M.MjaVIII, M.MjaVIII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RL21_YERP3
Sequence: MYAVFQSGGKQHRVSEGQTIRLEKLDIATGETIEFDQVLMIANGEEINIGAPLVDGGKIKAEIIAHGRGEKIKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YPQQ_PSEPH
Sequence: MSYEPATAATVAGLSVSGVKTMRVALYQCPPRPLDVAGNLQRLHQVAMEATDADLLVLPEMFLSGYNIGLEAVGALAEAQDGPSAQRIAAIAQAAGTAILYGYPERSVDGQIYNAVQLIDAQGQRLCNYRKTHLFGDLDHSMFSAGEDDFPLVELDGWKLGFLICYDIEFPENARRLALAGAELILVPTANMIPYDFVADVTIRARAFENQCYVAYANYCGHEEQIRYCGQSSIAAPDGSRIALAGLDEALIIGTLDRQLMGESRALNRYLSDRRPELYDDLSKR
What are the official names of this protein?
Hydrolase in pqqF 5'region, ORF2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: CWP13_PHAVU
Sequence: NYDKNFYEDTLP
What are the official names of this protein?
33 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: GLHA_MESAU
Sequence: MDYYRKYAAVILVVLSMFLHILHSLPDGDFMIQGCPECKLKENKYFSKLGAPIYQCMGCCFSSAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTEC_BACSU
Sequence: MFEKISQFLVPIAGRLNNNRYLQVLRDAFMLAFPLTIFGSIFVVLTNLPFLNKIMNASMLTSFQSHFGIASTATMGIMSVFVVFGIGYYLSKSYQVEAVFGGAIALVSFLLLTPFIIQPETGDAITGVIPVDRLGAKGMFLGMITAFLSGEIYRRIVQKNLTIKMPAGVPPAVAKSFAALIPAFITLTVFLLINVMVTLFFKTNMHDVIYHAIQAPLVGLGSGIIPTLIAVFFIQILWFFGLHGQIIINSVMDPIWNTLQVENLSAYTAGKEIPHIISKPFMEIYTVGMGGTGMTLAIVFTILIFMKSRQMKQVSKLGLAPGIFNVNEPIIFGLPIVMNPIIIVPWVLAPMVVTLVTYLAMSAGLVPPPTGVTVPWTVPLFINGIMATNSIMGGVMQLINLLIVFVIWFPFLKAMDKLNLAKEKEQAVQETAAQQNDNSIKM
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II GmuABC PTS system is involved in the transport of oligo-glucomannans such as cellobiose or mannobiose.
What are the official names of this protein?
PTS system oligo-beta-mannoside-specific EIIC component, Glucomannan utilization protein C, Oligo-beta-mannoside permease IIC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDEB_BORBU
Sequence: MQNSESIIKNIKNSSYLIDKEFLVWPENAFIGDKNIELIEKWNLKSYIKERKNFFSDDSVKKEYEEIHKKFNEEAISSYHVIISNLEEIYENCKRNKKIYYQDIMPTVKKVIEFYKKQKKIFIKYFRIPKLSANYHIIHSVNTAILTVALGNEMGLNNYKTVELCSIALLHKIGFLFIPSKISEKKEALTEEELEIIKKYPIISYKIASTSNLSRSICLTLLTHKENLDGTGYPKGLTSENISIESNIIGAASAYSAIILDKAYKKSFNSGASIIELIKDADKKFDKRVLKLIINAISSCPLDFIVELNDNSIAKIVDIDESNPNLPYINYIIKNGKVIDKNEQSSVQSIPNTNTGIKKILNQNEIELIKNKYSLIDII
What is the function of this protein?
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP.
What are the official names of this protein?
Cyclic di-GMP phosphodiesterase PdeB.
Protein: PSBM_ORYSJ
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HIS2_THEVB
Sequence: MPATALSLPLDEIRYDERGLVPAIVQDYLDGTVLMLAWMNRESLQKTLETGRTWFWSRSRQELWPKGETSGHVQWVKSIRYDCDSDALLLTVEQVGHIACHTGERSCFHRHGAKGESIEPPPADTLSQVYNIVCQRRDFPQLQSYTSSLFTAGDNKILKKLGEETAEVVMACKDDDPEAIASEVADLFYHTLVALAYHRVSLRQVYEQLQLRRR
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.