PharMolix/UniProtQA huggingface dataset:
Protein: HUGA_POLPI
Sequence: GETISIYYDPGKFPALMPLKNGNYEERNGGVPQRGNITIHLQQFNEDLDKMTPDKNFGGIGVIDFERWKPIFRQNWGNTEIHKKYSIELVRYEHPKWSESMIEAEATKKFEKYARLFMEETLKLAKKTRKRAKWGYYGFPYCYNYTPNNPGPDCDAKAMIENDRLSWMYNNQEILFPSVYVRHELTPDQRVYLVQGRIKEAVRISNNLKHSPKVLSYWWYVYQDKMDIFLSETDVKKTFQEIVTNGGDGIIIWGSSSDVNSLSKCKRLREYLLNTLGPFAVNVTETVN
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase, Hya, Hyaluronoglucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SAT_BACC4
Sequence: MSIVNGLVNRIDETYDVSQIEKEIKLDNIALSDLELLATGGYSPLTGFLGEEDYDSVVETLRLANGSVWSIPITLPVTEKVAESLKAGEEVKLVNNGNIYGVIQIEDIFVPDKEKEALLVYKTTDEAHPGVKKLYERPNVYVGGTIILTKRFENNQFPSYHLDPIETREAFKKRGWKTVVGFQTRNPVHRAHEYIQKSALEIVDGLFLNPLVGETKSDDIPADVRMESYEVLLQNYYPKNRVFLSVFPAAMRYAGPREAIFHALVRKNFGCTHFIVGRDHAGVGDYYGTYEAQEIFTNFTIEELGITPLFFEHSFYCTKCEAMASTKTCPHGKEDHVILSGTKVRELLRNGEIPPSTFSRKEVVEVLIKGLKKEVVTE
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: CO9A3_CHICK
Sequence: MTVFPTLGLLFLCQLLATTSAQRVGPQGPPGPRGPPGPSGKDGIDGEPGPSGLPGPPGPKGAPGKPGAAGEAGLPGLPGVDGLTGTDGPPGPNGPPGDRGALGPAGPPGPAGKGLPGPPGPPGPSGLPGGNGFRGPPGPSGLPGFPGPPGPPGPPGLAGIIPEGGGDLQCPALCPPGPPGPPGMPGFKGHTGHKGGPGEIGKEGEKGSPGPPGPPGIPGSVGLQGPRGLRGLPGPMGPAGDRGDIGFRGPPGIPGPPGRAGDQGNKGPQGFRGPKGDTGRPGPKGNPGARGLIGEPGIPGKDGRDGAPGLDGEKGDAARMGVPGEKGPNGLPGLPGRAGIKGSKGEPGSPGEMGEAGPSGEPGIPGDVGIPGDRGLPGPRGATGPVGLPGPIGAPGVRGFQGPKGSSGEPGLPGPTGIRGESGDRGPAGVIGAKGSQGIAGADGLPGDKGELGPFGPPGQKGEPGKRGELGPKGAQGPNGTAGAPGIPGHPGPMGHQGEQGVPGITGKPGPPGKEASEQHIRELCGEMINDQIAQLAANLRKPLSPGMTGRPGPAGPPGPPGATGSVGHPGARGPPGYRGPTGELGDPGPRGDTGEKGDKGPAGQGIDGPDGDQGPQGLPGVPGISKNGRDGAQGEPGLPGDPGTPGAVGAQGTPGICDTSACMGAVGASTSKKS
What is the function of this protein?
Collagen type IX is a minor cartilage non-fibrillar collagen.  It is associated with type II collagen fibrils.
What are the official names of this protein?
Collagen alpha-3(IX) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CCND3_MOUSE
Sequence: MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLGACSMSADELTELLAGITGTEVDCLRACQEQIEAALRESLREAAQTAPSPVPKAPRGSSSQGPSQTSTPTDVTAIHL
What is the function of this protein?
Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.  Shows transcriptional coactivator activity with ATF5 independently of CDK4.
What are the official names of this protein?
G1/S-specific cyclin-D3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MYG_BALBO
Sequence: MVLSDAEWQLVLNIWAKVEADVAGHGQDILIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSRHPGDFGADAQAAMNKALELFRKDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL3_BORPE
Sequence: MEKTMSNSTPTPAAHRLGLVGRKVGMTRIFTEDGESIPVTVLDVSNNRVTQVKSLESDGYAAIQVTYGTRRATRVVKPQAGHYAKAGAEAGSILKEFRLDPARAAEFAAGAVIAVESVFEAGQQVDVTGTSIGKGFAGTIKRHNFGSQRASHGNSRSHRVPGSIGQAQDPGRIFPGKRMSGHMGDVTRTVQNLDVVRVDAERGLLMVKGAVPGHAGGDVIVRPAVKAPAKKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YPCB_ECOLX
Sequence: IQNDTGLPEESICSFRFLWRSTSVDDAVQIHWANGNIQVIRPVRGISINGEAQGGIRPPYWVILAFCRSADGRIICSEGYAHALYQLTCPVPVDSKLERNTLTALLNVASWLKRKPGTPELSLERPLFDTEVYVNGEKKYVLPDFIVTARAPDGKTARVVIETMGYEDSDYCARKSRQHTGMKQIGELHTDPPKWLDNDHPPFKKHMYGVFMHLRY
What are the official names of this protein?
Uncharacterized protein in cib 5'region.
What is the protein family that this protein belongs to?
Belongs to the channel forming colicin family.
Protein: RS6_APLCA
Sequence: MKLNISYPATGCQKLIEVDDEKKLRPFYDKRISAELSADCLGDEWKGYVVRISGGNDKQGFPMKQGVLTATRVRLLLDKNHSCYRPRRTGERKRKSVRGCIVDSNLSVLSLVIIKKGEQDIPGLTDKTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPERDGKKAKSKAPKIQRLVTPVVLQRKRARMALKKKRVTKKREDHAEYTKLLAQRMKEAKERKMERKRSNSRSKGDSIRESTSKK
What is the function of this protein?
Component of the 40S small ribosomal subunit (By similarity).  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity).
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: PHO12_ORYSJ
Sequence: MVKFSREYEASIIPEWKAAFVDYKRLKKLIKRIKVTRRDDSFAAANAAAAADHLLPPPPAEKEAGGYGFSILDPVRAIAARFSAGQQPSASEDEECPDRGELVRSTDKHEREFMERADEELEKVNAFYTGQEAELLARGDALLEQLRILADVKRILADHAAARRARGLARSRSMPPPPPSSSPPSSVHGSSGRYLLSGLSSPQSMSDGSLELQQAQVSEGAAVADEVMAALERNGVSFVGLAGKKDGKTKDGSGKGRGGGGGGGGGVLQLPATVRIDIPATSPGRAALKVWEELVNVLRKDGADPAAAFVHRKKIQHAEKNIRDAFMALYRGLELLKKFSSLNVKAFTKILKKFVKVSEQQRATDLFSEKVKRSPFSSSDKVLQLADEVECIFMKHFTGNDRKVAMKYLKPQQPRNTHMITFLVGLFTGTFVSLFIIYAILAHVSGIFTSTGNSAYMEIVYHVFSMFALISLHIFLYGCNLFMWKNTRINHNFIFDFSSNTALTHRDAFLMSASIMCTVVAALVINLFLKNAGVAYANALPGALLLLSTGVLFCPFDIFYRSTRYCFMRVMRNIIFSPFYKVLMADFFMADQLTSQIPLLRHMEFTACYFMAGSFRTHPYETCTSGQQYKHLAYVISFLPYFWRALQCLRRYLEEGHDINQLANAGKYVSAMVAAAVRFKYAATPTPFWVWMVIISSSGATIYQLYWDFVKDWGFLNPKSKNRWLRNELILKNKSIYYVSMMLNLALRLAWTESVMKIHIGKVESRLLDFSLASLEIIRRGHWNFYRLENEHLNNVGKFRAVKTVPLPFRELETD
What is the function of this protein?
Involved in the transfer of inorganic phosphate (Pi) from roots to shoots.
What are the official names of this protein?
Phosphate transporter PHO1-2, Protein PHO1-2, OsPHO1;2.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPH4_CANGA
Sequence: MTVKSKSRISHYEVLGVPVDASTDEIKLTYRKMLLTLHPDKSKTVPIDSTIKIRSGVSINQIQEAYRVLSNDQLRAAYNRALNDSNKLAGFNNFGDGLDEFNLDEFEFNEEKLEYVMTCPRCQSGGGFVLSEDMLEECIEDGLTESEEQGYQVLTQCTACSLWLKVNFFINDEEE
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue.  Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).
What are the official names of this protein?
Diphthamide biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the DPH4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PHAR3_HUMAN
Sequence: MAASEDGSGCLVSRGRSQSDPSVLTDSSATSSADAGENPDEMDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
What are the official names of this protein?
Phosphatase and actin regulator 3, Scaffold-associated PP1-inhibiting protein, Scapinin.
What is the protein family that this protein belongs to?
Belongs to the phosphatase and actin regulator family.
What are the subcellular locations of this protein?
Nucleus matrix. Note=Localized to the nuclear matrix-intermediate filament scaffold. Isoform 2 is also found in some cytoplasmic extensions.
Protein: O16A_CONSC
Sequence: CAGIGSFCGLPGLVDCCSDRCFIVCLP
What is the function of this protein?
This toxin activates voltage-gated sodium channels (Nav1. 3/SCN3A (EC(50)=3. 98 nM), Nav1. 4/SCN4A (EC(50)=4. 99 nM), Nav1. 6/SCN8A (EC(50)=1. 27 nM) and Nav1. 7/SCN9A (EC(50)=2. 42 nM)).  It shifts the voltage-dependence of activation to more hyperpolarized potentials but has only little effect on channel inactivation.  In vivo, it induces nocifensive or pain-like behaviors in mice when injected intraplantarly.  This is coherent with the specific defensive role deduced from its proximal position in the venom gland.
What are the official names of this protein?
Delta-conotoxin SuVIA, Delta-SuVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCA_BAUCH
Sequence: MKKYLVGGAVRDRLLQIPVKERDWVVIGTTLQDMLKAGYQQVGKDFPVFLHPKSHEEYALARIEKKSATGGYTGFTYKASSEITLEEDLKRRDLTINAIACDENGSLIDPYNGQRDLNQRWLRHVSEAFCEDPLRVLRVARFAAQLAYLNFRIVPETRLMMQHMISELPLLSPERIWKETEKALATRDPQIYFQVLRDCGALKTLFPEIDALFGVPAPAKWHPEIDTGIHTMMTVAMAARLSDSIAVRFASLCHDIGKGLTPRDHWPSHHGHGPAGIPLVQSLCQRLRVPNSIRNLAIIVTEYHDLLHYAVKLKPKTLIKLFYAIDVWRRPERLEQIIIISEADARGRAGYENHFYKPGQFIREAYRIASSIMPCQVISHNLTGNKIGEKLRQYRQQAIATWKQQNYESKQQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MCM3_YEAST
Sequence: MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSGSPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQLGLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTISTGRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNNLMVADDKVWRV
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity.  Necessary for cell growth.
What are the official names of this protein?
DNA replication licensing factor MCM3, Minichromosome maintenance protein 3.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCXT2_MESMA
Sequence: VRDAYIAKPENCVYHCAGNEGCNNLCTCNGAT
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin dose-dependently delays inactivation of voltage-gated sodium channels (Nav) (EC(50)=0. 91 uM), and shifts the steady-state activation and inactivation to hyperpolarized direction.  In addition, it dose-dependently alters calcium dynamics and increases phosphorylation of MAP kinases 1/3 (MAPK1/MAPK3) and cAMP-response element binding (CREB) proteins in neocortical neurons.  This effect is eliminated by tetrodotoxin, a Nav blocker.
What are the official names of this protein?
Sodium channel neurotoxin BmK NT2, Alpha-scorpion toxin.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_CASEQ
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGVTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYFEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECO_PSE14
Sequence: MSAPTGQPAYVLHSRAYRENSALVDFLTPQGRLRAVLRSAKGKAGSLARPFVPLEVEFRGRGELKNVGRMESAGVATWMTGEALFSGMYLNELLIRLLPAEDPHPAVFEHYAATLLALALGRPLEPLLRSFEWRLLDDLGYGFAMDADINGEPLAIDGMYRLQVDAGLERVYLLQPGLFQGAELLAMSEADWSVPGALSAAKRLMRQALAVHLGGRPLVSRELFRKP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RPOB_PHEZH
Sequence: MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSVFPIKDFNERAVLEYVSYEFEEPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSVKDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPGVFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKGDGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEALTGRYLAKDLVNFETGEIYAEAGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLRVDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDSERYDLSSVGRVKMNMRLELDCPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYRRIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDLVPGRINGEPSLLPKADVDLMDVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSGAVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVGDKINAGDVIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEIDRLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIALDDEKAMGELEALRKQFDDARKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLGVPSRMNVGQIFETHLGWAAAGLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPVFDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: 3BHS5_RAT
Sequence: MPGWSCLVTGAGGFLGQRIVQMLVQEKELQEVRVLYRTFSPKHKEELSKLQTKAKVTVLRGDIVDAQFLRRACQGMSVIIHTAAALDIAGFLPRQTILDVNVKGTQLLLDACVEASVPAFIYSSSTGVAGPNSYKETILNDREEEHRESTWSNPYPYSKRMAEKAVLAANGSILKNGGTFHTCALRLPFIYGEESQIISTMVNRALKNNSIIKRHATFSIANPVYVGNAAWAHILAARGLRDPEKSQSIQGQFYYISDDTPHQSYDDLNYTLSKEWGFCLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFNRFMVTILNSVFTISYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
What is the function of this protein?
Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids.  Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR.  Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone.  Does not function as an isomerase.
What are the official names of this protein?
NADPH-dependent 3-keto-steroid reductase Hsd3b5, 3 beta-hydroxysteroid dehydrogenase type 3, 3 beta-hydroxysteroid dehydrogenase type III, 3 beta-HSD III, Dihydrotestosterone 3-ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: LPXD_PSEE4
Sequence: MTVTMTLGQLAEALGATLKGPEALQITGLATLQEAGSGQLSFLANKQYRKFLESSQASAVLLKAEDAEGFAGNALIVADPYLAYARISHLFDPKPKAVAGIHPSAVVAEDAQVDTSASIGPFAVIESGARIGADVTIGAHCFIGARCVVGEGGWLAPRVTLYHDVIIGKRVVIQSGAVIGGEGFGFANEKGIWRKIAQIGGVTLGDDVEIGVNTAVDRGALSDTRIGDGVKLDNQIQIAHNVQVGDHTAMAACVGISGSTRIGKHCMIAGGVGMVGHIDVCDNVFVSGMTMVTRSITEPGGYSSGTAMQPLAEWRKSAARIRQLDEMSKRLQQLEKRVDTVTSGGQPTSEG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DAPE_AGRVS
Sequence: MSKHPANSSATDPVDNLQTLIRCPSVTPAEGGALSALAAMLEPLGFTVERMVAREEGTPDVENLYARLGTEGPHLMFAGHTDVVPVGNEADWTYPPFSAEIAGGELYGRGAVDMKGGIACFVAAIARHIESQGAPKGSISFLITGDEEGPSINGTTKLLEWAAAKGERWDACLVGEPTNPDQLGDMIKIGRRGSLSGEIIVKGVQGHAAYPHLADNPVRGMIKLAEALMHPAFDAGTENFQPSNLEVTTIDVGNAATNVIPARASAKFNIRFNDTWTAETLRTEIIARLDTASADPLLRPGRPPIAYELVWADRPSQVFLTRNNALISSLSAAIEKMTGKTPALSTTGGTSDARFIKDYCPVVEFGLVGQTMHMVDERVAVSDLEALTGIYGAFISSWFTHAGA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RPOB_ACIB3
Sequence: MAYSYTEKKRIRKNFGKLPQVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSVFPIESYSGNAALEFVEYSLGKPEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVREQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYSARIIPYRGSWLDFEFDAKDLVYVRIDRRRKLLATVVLRALGYNNEQILNLFYEKVPVYLDMGSYQIDLVPERLRGEMAQFDITDNEGKVIVEQGKRINARHVRQMEAAGLTKLSVPDEYLYERITAEDITLRDGEVIAANTLLSHEVMVKLAEGGVKQFNILFTNDIDRGSFVADTLRADLTRDREEALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSPVGRMKFNRRLGRPYEVGTDQKSREVEGILSHEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRVERAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHQTHYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPYRKVVDGRVTDDVEYLSAIEEVGTVIAQADSAVDKDGNLTEEFVSVRHQGEFVRMPPEKVTHMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMEANVARDSGVCVIANRGGVIEYVDASRIVIRVNEDEMVAGEAGVDIYNLIKYTRSNQNTCINQNVIVNLGDKVARGDILADGPSTDMGELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVYIGAEVTAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKAQLDSYRKDLKEEYKIFEEAARERVIRLLKGQESNGGGSTKRGDKLSEDLLSGLELVDLLEIQPADEAIAERLTQIQVFLKEKSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRRIQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDIVLNPLGVPSRMNVGQILETHLGMAAKGLGDKIEKMLKEQRTVLELREFLDKIYNKVGGEQEDLDSLTDEEILALAGNLRAGVPLATPVFDGAEESQIKDLLELADISRTGQTVLFDGRTGEQFDRPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGRTRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKNGD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.