PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_ZYMMO
Sequence: MATASSKKNIGRISQVIGPVVDVLFEEKLPPLLTALETKNQDATVVLEVAQHLGENVVRTISMDTTDGLVRGQEVVDTGSEIRVPVGPETLGRIMNVVGRPVDERGPIGSKQTMPIHADAPPFTEQSTDTAILTTGIKVIDLLAPYSKGGKVGLFGGAGVGKTVLIQELINNIAKGHGGFSVFAGVGERTREGNDLYHEFLEAGVIASDKDGNAISEGSKVALVYGQMNEPPGARARVALSGLTMAEYFRDQEGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGQLQERITSTKKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRAISEMGIYPAVDPLDSSSRNLEPRIVGDEHYQTARDVQEILQRYKNLQDIIAILGMDELSEDDRKVVGRARRIQRFLSQPFHVAEVFTGMPGKFVQVEDTVRSFREIIDGKYDDLPENAFYMVGSIDEAVAKAEKMAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GCH1_RICRO
Sequence: MSKPTREEAKEAVRTLLKFIGEDPSREGLLKTPDRVINSYAEIFSGYGKDVAEILNTKFYETCNFRDFILLNIKFTSFCEHHILPFNGTVDIAYVPDNCIVGISKLARIVNIFARRLQIQEKMTVQIAESVQENLKPLGVAVKISAVHSCMSMRGVMQDNSVMNTMHYTGIFAEQQKYRHEFLNLTAKR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RSMG_OCEIH
Sequence: MKPEQFVHALKEKGINLSEKQTEQFYIYFQELVEWNQKVNLTAITDQEEVYVKHFYDCVTAAFYHDFNQEISICDIGAGAGFPSIPLKIVFPQLKITIVDSLKKRITFLNHLATKLELSNVAFYHDRAENFGKNKTFRESFDIVTARAVARMSVLSELCLPLVKKNGVFIAMKGAQAKEELEVGKPAIELLGGEVEEIHTFSLPIEESERSIILISKKRQTPKKYPRKAGLPNKEPIE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTG1_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMWYFDGTACTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1g, U15-TRTX-Hhn1g, Kunitz-type serine protease inhibitor hainantoxin-XI-7, HNTX-XI-7.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RASF7_HUMAN
Sequence: MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQPQAL
What is the function of this protein?
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK.  Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway.  Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
What are the official names of this protein?
Ras association domain-containing protein 7, HRAS1-related cluster protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with gamma-tubulin.
Protein: Y1706_STAA2
Sequence: MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
What are the official names of this protein?
UPF0473 protein SaurJH1_1706.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: BAME1_ARATH
Sequence: MKLFLLLLFLLHISHTFTASRPISEFRALLSLKTSLTGAGDDKNSPLSSWKVSTSFCTWIGVTCDVSRRHVTSLDLSGLNLSGTLSPDVSHLRLLQNLSLAENLISGPIPPEISSLSGLRHLNLSNNVFNGSFPDEISSGLVNLRVLDVYNNNLTGDLPVSVTNLTQLRHLHLGGNYFAGKIPPSYGSWPVIEYLAVSGNELVGKIPPEIGNLTTLRELYIGYYNAFEDGLPPEIGNLSELVRFDGANCGLTGEIPPEIGKLQKLDTLFLQVNVFSGPLTWELGTLSSLKSMDLSNNMFTGEIPASFAELKNLTLLNLFRNKLHGEIPEFIGDLPELEVLQLWENNFTGSIPQKLGENGKLNLVDLSSNKLTGTLPPNMCSGNKLETLITLGNFLFGSIPDSLGKCESLTRIRMGENFLNGSIPKGLFGLPKLTQVELQDNYLSGELPVAGGVSVNLGQISLSNNQLSGPLPPAIGNFTGVQKLLLDGNKFQGPIPSEVGKLQQLSKIDFSHNLFSGRIAPEISRCKLLTFVDLSRNELSGEIPNEITAMKILNYLNLSRNHLVGSIPGSISSMQSLTSLDFSYNNLSGLVPGTGQFSYFNYTSFLGNPDLCGPYLGPCKDGVAKGGHQSHSKGPLSASMKLLLVLGLLVCSIAFAVVAIIKARSLKKASESRAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGVMPNGDLVAVKRLAAMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELVTGRKPVGEFGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVERPTMREVVQILTEIPKLPPSKDQPMTESAPESELSPKSGVQSPPDLLNL
What is the function of this protein?
Necessary for male gametophyte development, as well as ovule specification and function.  Involved in cell-cell communication process required during early anther development, and regulating cell division and differentiation to organize cell layers.  Required for the development of high-ordered vascular strands within the leaf and a correlated control of leaf shape, size and symmetry.  May regulate the CLV1-dependent CLV3-mediated signaling in meristems maintenance.
What are the official names of this protein?
Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1, Protein BARELY ANY MERISTEM 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RNFA_HAEIN
Sequence: MTHYILLIIGTALINNFVLVKFLGLCPFMGVSKKIETAVGMGLATMFVLTVASLCAYLVDHYILIPLNATFLRTLVFILVIAVVVQFTEMAINKTSPTLYRLLGIFLPLITTNCAVLGVALLNVNLAHNLTESVVYGFGASLGFSLVLVLFAALRERLVAADIPATFRGSSIALITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCC2A_MOUSE
Sequence: MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
What is the function of this protein?
Has no kinase activity.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
[Isoform Alpha KAP]: Cytoplasm. SUBCELLULAR LOCATION: Synapse. Postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Note=Postsynaptic lipid rafts.
Protein: MRAZ_STAA3
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: BLE_KLEPN
Sequence: MTDQATPNLPSRDFDSTAAFYERLGFGIVFRDAGWMILQRGDLMLEFFAHPGLDPLASWFSCCLRLDDLAEFYRQCKSVGIQETSSGYPRIHAPELQEWGGTMAALVDPDGTLLRLIQNELLAGIS
What is the function of this protein?
Binding protein with a strong affinity to the bleomycin family of antibiotics.  Binds to CL990; an antimitotic-antibiotic compound.
What are the official names of this protein?
Bleomycin resistance protein, BRP, CL990 resistance protein.
What is the protein family that this protein belongs to?
Belongs to the bleomycin resistance protein family.
Protein: RL11_AYWBP
Sequence: MAKKVVKTVKLQIPAGKANPAPPVGPALGQAQVNIPSFCSQFNETTKDQMGFVIPVIISVYEDRTFTFVTKTPPASDLLKKAAKIESGSANASQTKVATITHKQVEEIANLKLSDLNAYCVEKACKIIEGTARNMGILVKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RECA_STRPQ
Sequence: MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_MYCSK
Sequence: MTDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDLQAQIDKWHRQRAIGPHDADEYKQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSYNRVRGDKVIAYAREFLDGAAPLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLHIEILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGDLSEEVSKGDKTFTRVLNPDRTYTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNEVFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVKPKMHGPAEVAYTVDLFSRVEDVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMIRKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREEVDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATLRISSQLLANWLRHGVITEEDVKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRRRREYKASVAGA
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_METM5
Sequence: MNEDIKNNLNNSDESNGKIIVGLDEAGRGPVIGPMVIASVKINEKDLPRLDDLGLRDSKQLSKKKREELYTKISEICDVKKVVINPEKIDEQMEIINLNKIELGAFSKLANHFIKENENISIYIDACSSNEQSFSNQFKAKLINKNVEIIAEHKADENYKIVSAASIIAKVTRDNVIEEYKKTFGEIGSGYPSDPKTKKFLKNYVHENKGLPKIARKSWATSKNLLKEIEESKIFQWVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEI_SALAR
Sequence: MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKFPQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGKIKLKDFNITTDLGPASQEVELIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: YDHR_ECOLI
Sequence: MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
What is the function of this protein?
May function as monooxygenase and play a role in the metabolism of aromatic compounds.
What are the official names of this protein?
Putative monooxygenase YdhR.
Protein: RS7_MYCPU
Sequence: MSRKHKAPIRTVLADPVFNMVVVTKLVNTIMLDGKKSIAQNIVYSAFDIIKEKTGREPYEVFQEALNNITPLLEIRTRRIGGSNYQVPTEVSKRRQQTLSLRWLTNYARLRNEKTMDLRLANEIIDASNKTGGAIKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: IFRH1_PSEMZ
Sequence: GVYVIEEDVATYTIK
What are the official names of this protein?
Isoflavone reductase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2082_MYCTU
Sequence: MAGDLPPGRWSALLVGAWWPARPDAPMAGVTYWRKAAQLKRNEANDLRNERSLLAVNQGRTADDLLERYWRGEQRLATIAHQCEVKSDQSEQVADAVNYLRDRLTEIAQSGNQQINQILAGKGPIEAKVAAVNAVIEQSNAMADHVGATAMSNIIDATQRVFDETIGGDAHTWLRDHGVSLDTPARPRPVTAEDMTSMTANSPAGSPFGAAPSAPSHSTTTSGPPTAPTPTSPFGTAPMVLSSSSTSSGPPTAPTPTSPFGTAPMPPGPPPPGTVSPPLPPSAPAVGVGGPSVPAAGMPPAAAAATAPLSPQSLGQSFTTGMTTGTPAAAGAQALSAGALHAATEPLPPPAPPPTTPTVTTPTVATATTAGIPHIPDSAPTPSPAPIAPPTTDNASAMTPIAPMVANGPPASPAPPAAAPAGPLPAYGADLRPPVTTPPATPPTPTGPISGAAVTPSSPAAGGSLMSPVVNKSTAPATTQAQPSNPTPPLASATAAATTGAAAGDTSRRAAEQQRLRRILDTVARQEPGLSWAAGLRDNGQTTLLVTDLASGWIPPHIRLPAHITLLEPAPRRRHATVTDLLGTTTVAAAHHPHGYLSQPDPDTPALTGDRTARIAPTIDELGPTLVETVRRHDTLPPIAQAVVVAATRNYGVPDNETDLLHHKTTEIHQAVLTTYPNHDIATVVDWMLLAAINALIAGDQSGANYHLAWAIAAISTRRSR
What are the official names of this protein?
Uncharacterized protein Rv2082.
Protein: LEF1_RAT
Sequence: MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVVGQTQSSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNSDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSEVNPKQGMSRHPPAPEMPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQAYPSSLSGDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPEHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI
What is the function of this protein?
Transcription factor that binds DNA in a sequence-specific manner (By similarity).  Participates in the Wnt signaling pathway (By similarity).  Activates transcription of target genes in the presence of CTNNB1 and EP300 (By similarity).  PIASG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).  TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity).  Regulates T-cell receptor alpha enhancer function (By similarity).  Required for IL17A expressing gamma-delta T-cell maturation and development, via binding to regulator loci of BLK to modulate expression (By similarity).  May play a role in hair cell differentiation and follicle morphogenesis (By similarity).
What are the official names of this protein?
Lymphoid enhancer-binding factor 1, LEF-1.
What is the protein family that this protein belongs to?
Belongs to the TCF/LEF family.
What are the subcellular locations of this protein?
Nucleus. Note=Found in nuclear bodies upon PIASG binding.
Protein: TM2D2_PONAB
Sequence: MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSQNATAEPELTSAGAAQPEGPGAAASWEYSDPHSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALAGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
What are the official names of this protein?
TM2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSLO_SHIFL
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNTQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADP
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP22_HHV11
Sequence: MTSRRSVKSGPREVPRDEYEDLYYTPSSGMASPDSPPDTSRRGALQTRSRQRGEVRFVQYDESDYALYGGSSSEDDEHPEVPRTRRPVSGAVLSGPGPARAPPPPAGSGGAGRTPTTAPRAPRTQRVATKAPAAPAAETTRGRKSAQPESAALPDAPASTAPTRSKTPAQGLARKLHFSTAPPNPDAPWTPRVAGFNKRVFCAAVGRLAAMHARMAAVQLWDMSRPRTDEDLNELLGITTIRVTVCEGKNLLQRANELVNPDVVQDVDAATATRGRSAASRPTERPRAPARSASRPRRPVE
What is the function of this protein?
Tegument protein that plays different roles during the time course of infection (PubMed:22993164, PubMed:24131716, PubMed:9658087, PubMed:11967313).  Participates in both the accumulation of viral mRNAs and viral protein translation at late time of infection (PubMed:22993164, PubMed:24131716, PubMed:9658087, PubMed:11967313).  Modulates the RNase activity of the virion host shutoff protein UL41 probably to ensure necessary levels of key cellular mRNAs and proteins (PubMed:22951838).  Plays a role in microtubule reorganization that occurs after viral infection by stabilizing microtubule network (PubMed:9658087, PubMed:11967313).  Finally, may prevent nucleosomal deposition onto the viral genome by interacting with and inhibiting host SET (PubMed:12917472).  Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA (PubMed:29793952, PubMed:34015248).  Acts by mediating disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity (PubMed:34015248).
What are the official names of this protein?
Tegument protein VP22.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae VP22 tegument protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus. Note=One of the most abundant tegument protein (about 2000 copies per virion). Localizes in the cytoplasm at 8 hours postinfection and in the nucleus at 16 hours postinfection. During virion morphogenesis, this protein probably accumulates at the trans-Golgi where secondary envelopment occurs.
Protein: CUER_YERPE
Sequence: MNISDVAKKTGLTSKAIRFYEEKKLVTPPVRTDNGYRSYTAKHIEELTLLRQARQVGFTLDECRELLALFHNPARHSADVKAATLLKVAEIEQHINDLNQMRMRLLALAEECPGDEGADCPIINSLAGCCHSSSSLPLK
What is the function of this protein?
Regulates the transcription of the copA and cueO genes.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CueR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_FRATM
Sequence: MKKLNIIFAGTPDISAQVLKDLYKSQYNIQAVLTQPDRAKGRGKKVQFSPVKEVALANHTPVFQPLSFKKNPEVLEQIKQLKPDVIVVIAYGIIVPQEFLDIPRYGCLNIHVSLLPKWRGAAPIQRAIQAGDTKTGVCIMQMDAGLDTGDILNTLEIEIQETDTSQTLHDKFAKLSIKPLLETLEKIEIIKPEPQQGEPTYAHKITKQEGLIDFTKSAWQISCHIRAFTPWPGAYFILDDEAIKVGEFEILYQNTDNRKAGTIIDIYRSGFDIATSDKIIRFRQLQFPNKKMLNIVDILNGKDLDKYIGYKLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HPRK_LEPBA
Sequence: MPVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQILGKGEWAYLNSLSEEKLGEITDKFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIATHRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRSGVGKSETALELIERGHRLVADDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEWEEQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAKEFSNKLNTYIQQSSIETNPIKD
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: TLP_BACAN
Sequence: MPNPDNRSDNAEKLQEMVQNTIDNFNEAKETAELSNEKDRSAIEAKNQRRLESIDSLKSEIKDES
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: SC23A_HUMAN
Sequence: MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPLTQATRGPQVQQPPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGRGAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.  Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane (By similarity).
What are the official names of this protein?
Protein transport protein Sec23A, hSec23A, SEC23-related protein A.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Note=Enriched at endoplasmic reticulum exit sites, also known as transitional endoplasmic reticulum (tER).