PharMolix/UniProtQA huggingface dataset:
Protein: PALY1_PLEOS
Sequence: MTILSADTLSITRPYSNSLSTLKVIATPVTESPPSPVASSISPNATNLVEEFINAHKELQSYKSGRPVVLDGHTLSIAAVAAAARYDAGVELDDSPLVKDRLLQSRQVVADKVEQGTSIYGVTTGFGGSADTRTDQPILLGNALMQMQHSGILPSSSKPLDALPLQDPFGLAMPESWVRGAMLIRMNSLIRGHSGVRWELIEKMNDLLRANITPVVPLRGSISASGDLQPLSYVAGALYGNPSIRVFDGERTSALGPRKIVSSVEALEAHSISPISLACKEHLGILNGTAFSASVAALALHDAVHLTLLTQVLTAMGAEALAGTRGNFDPFIHAVARPHPGQIETADVIWNLLEGSKFATTEEEEMTIDEDKGHLRQDRYPLRTSPQFIGPQVEDLIASLATITLECNSTTDNPLVDGETGKVHNGGNFQAMAVTNAMEKTRLSLHHLGKLVFSQCAELINPTMNRGLPPSLAATDPSLNYHAKGIDIASAAYVAELGYLANPVSTHIQSAEMHNQAINSMALVSGRATITSLEVLSLLISSYLYAICQALDLRALQHELYEGLDAIVKEEIIAAFSPFLDDYEITRFTAISCHIVRDAMDSTSTMDAKDRMTSVAASLTTPLVDFLTGEAFSDVVSAGQALTTIPAFRARIAARGYELLDELRRAYLSGGRGLAPASRFLNKTRPVYEFVRLTLGIKMHGAENYNDFENGVGVDDVTTGQNVSLIHEAIRDGKLQPIIVDLF
What is the function of this protein?
Catalyzes the non-oxidative deamination of L-phenylalanine to form trans-cinnamic acid and a free ammonium ion (PubMed:31655558).  Facilitates the commitment step in phenylpropanoid pathways that produce secondary metabolites such as lignins, coumarins and flavonoids (By similarity).
What are the official names of this protein?
Phenylalanine ammonia-lyase 1, PoPAL1.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KC1G1_MACFA
Sequence: MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQFSSSTNQTSNLK
What is the function of this protein?
Serine/threonine-protein kinase.  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling.  Regulates fast synaptic transmission mediated by glutamate.  Phosphorylates CLSPN (By similarity).
What are the official names of this protein?
Casein kinase I isoform gamma-1, CKI-gamma 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1074_ARCFU
Sequence: MPKIIEAIYENGVFKPLQKVDLKEGERVRIKLEKVEEVVDEVFGILKGKDTLKALRELEEWGFC
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Putative antitoxin AF_1074.
What is the protein family that this protein belongs to?
Belongs to the UPF0165 family.
Protein: HEM1_CHRVO
Sequence: MHLLAFGLNHHTAPLSIREKLAFPAETLPRALESLLASQAAREAAIVSTCNRTEIYCSSPDPHAALDWLCQFHGLSRAELEPYLYRLEASQAARHAFRVASGLDSMVLGETQILGQLKDAVRSAEHAGALGTLLNGLFQRTFAVAKEVRSSTAVGASSVSMSAAAVKLAEQIFPSVAELNVLFVGAGEMIELVATHFAARNPSCITVANRTLERGQRLAEQFGGNAITLAELPESLARYDVVVTSTASQLPIIGKGMVERAIKARRHRPMFMLDLAVPRDVELEVGKLDDVFLYSVDDIAGIVEVGKEARQNAAEEAETIIQARVAEFTDWLKKRETVPLIRALRDEADRARRHALEGALKQLARGDAPEKVLEALSVQLTNKLMHPPTQALSSGSGAEHDAQVQAIARLYRLHPES
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CRGD_MOUSE
Sequence: MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFTGCQYFLRRGDYPDYQQWMGFSDSVRSCRLIPHAGSHRIRLYEREEYRGQMIEFTEDCPSLQDRFHFNEIYSLNVLEGCWVLYDMTNYRGRQYLLRPGEYRRYHDWGAMNARVGSLRRVMDFY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: IHFA_CROS8
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKEN
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TCPA_VIBCH
Sequence: MQLLKQLFKKKFVKEEHDKKTGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNITHVEKLCTGTAPFTVAFGNS
What is the function of this protein?
Major component of the toxin co-regulated pilus (tcp) which is a type IV pilus essential for bacterial aggregation and subsequent colonization in the host small intestine.
What are the official names of this protein?
Toxin coregulated pilin, Pilus colonization factor.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: PHOSP_RABVB
Sequence: MSKIFVNPSAIRAGLADLEMAEETVDLIARNIEDNQAHLQGEPIEVDSLPEDMRRLQLDDTKPSGPGEIAATGESKCQEDFQMDEAEDPALLFQSYLDNVGIQIVRQMKSGERFLKIWSQTVEEIISYVTVNFPSLPGKSTEDKATQTASRELKKETVSAPSQRDSQSSKTKVAAQTASGPPALEWSTANEEDDPSVEAEIAHQIAESFSKKYKFPSRSSGIFLYNFEQLKMNLDDIVKESKNVPSVTRLAHDGSKLPLRCVLGWVALAKSKKFQLLVEPDKLNKIMQDDLNRYAFP
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA.  Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.  Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (By similarity).  Inhibits interferon induction pathways by interacting with host TBK1 and preventing the formation of dynamic cytoplasmic condensates that have liquid properties and that are essential for interferon production (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus protein P family.
What are the subcellular locations of this protein?
[Phosphoprotein]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P2]: Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P3]: Host nucleus. SUBCELLULAR LOCATION: [Isoform P5]: Host nucleus.
Protein: RR12_PELHO
Sequence: MPTSNQLLRNSRQPVRKTKKTPALRGCPQRRGRCSKVYIINPKKPNSGNRKVARVRLTSGFEITAYIPGVGHNVQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAAGVKDRKQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1740_DESRM
Sequence: MKLTFLGHSAFLLENQEVSLVIDPFLTGNPMAPHDIPVKPNYILVSHGHGDHLGDAIRLAKETSATIVSVFELANYCARQGVLTHPMHIGGSHNFGPMKVKLTQALHGNSTGSDRGPAEYLGNPCGFLIYLGNKTIYHAGDTGLFGDMQLIGDLNSIDVALLPIGDNFTMGPTDALEAVKMLKPQRVIPMHYNTWPLISQDPTAFKKAVEQATTTQVDILQPGEFLKI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Dred_1740.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PAN_METM6
Sequence: MSYPDDYSTDVEKNKMDLKEFKEKTQIAELESKVLRLELKNKDISRENVQIKKENEILKRELDKLRIPPLILGTILDRVNERKAVVKSSTGPNFLVNLSQFVDPEDIVPGARVCLNQQTLAIVEVLPKEKDYRAMAMEIEEKPDISFEDIGGLNNQIRDIKEVVELPLKNPELFEKVGIVPPKGVLLYGPPGTGKTLLAKAVAYETNASFVRVVGSELVKKFIGEGAKLVRDVFKLAKEKSPCIIFIDEIDAVASKRTESLTGGDREVQRTLMQLLAEMDGFDSRGDVKIIAATNRPDILDPAILRPGRFDRIIEISMPDEDGRLDILKIHTEKMNLKGVDLREVAKLAENMVGADLKAVCTEAGMFAIREEREFIKMDDFKEAISKITGKKEKCSYDMPQLTVMYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG9_GIBZE
Sequence: MASNIFSRIKSPSGGSQSFYQQLRSGEDPEYDPGLDEENLGHRFDDFQAEGMDIGDSSMTVESVAPGSKGKGKATFRPTAHARSSGITSPRWQQDDDGDNEVPASLLMEPKDLDPPASPPNKRATNPGSSRTPASVGPSSARTRAQWEAATAQQQLHQDHPYTTPMGPQPIPVARGTMSNNPREKALWRWVNTSNLDSFMRDVYDYFEGGGLWCILCANALWLFQCIDYSRVPDSRSLHEVIVPQCTRKMSGLWNFAIWLYTFFFIWKCVQYFVEIRRLTYIRDFYIYLLDIPEQDMQTISWQDVVARIMALREENPKTATNISPRLRQFMGSQSKERLDALDIANRLMRKENYLIAMINKDILDLSLPVPFLRGRQMFSKTMEWYLQYCILDMAFNELGQVQQDFLRPDRRRLLSQKLRQRFLFAGFLNLLFAPVVLAYVVIVYFFTYYYEYQKDPKQAAARKYTSLAEWKFRQFNELPHIFYERLHMSYPFATRYIDQFPKRITEAVARTIAFMSGAITAILAIGSVLDSELFLNFEITKDRPVIFYLGVFAAIWATTRGMVSEETLVFNPEYALRNVIEYTRYVPDHWKNKLHSSEVKQEFSELYKMKVVIFLEEMMGIVTTPMLLLFSLPRCSDQIVDFFREFTIHVDGLGYVCSFAVFDFQKGPGNTGPQGPRPDVREDYYSTKHGKMAASYYGFLDNYAANPKTGIPGHLPPGPKPSFHPPPSFPGIGSPTLAADMQGSHIGRTGTETGRARSRAPGGRGPRIGVMPQPSPMASMLLDQHHQPPGGNMVARSLHASRYPRGYRGESQIIEETEASSIRRNGEDDELYEPGGALGESVWETSPARGVTRENSAANTEDPEAGVLGLIYQLQQTQRPRRGGGMV
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236, PubMed:30044782).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).  Required for aerial hyphae development and lipid droplet degradation in response to starvation (PubMed:30044782).
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AZO1_STAAM
Sequence: MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPLNQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDYFKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLNDSEFQLRARLFVDQIVSFVNNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: NU3C_ADICA
Sequence: MFLSHQYDSFWIFLLVCISIPLLAFSITRFAAPPREGPEKSTSYESGIEPKGDTWIRFQIRYYMFALVFTVFDVETVFLYPWATSFEELGLFAFVEVIVFIFILIVGLVYAWRKGALEWC
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARGJ_ORYSI
Sequence: MPPPSLLLLHPRTPLPHHHRSSFRTSSPRPSRMVCAAAEGFISAAPILLPDGPWKQVEGGVTAAKGFKAAGIYGGLRAKGEKPDLALVACDVDATVAGAFTTNVVAAAPVLYCKRVLNSSKTARAVLINAGQANAATGDAGYQDTVDSADAVAKLLNVSTNDILIQSTGVIGQRIKKEALVNSLHRLVGSLSSSIEGANSAAVAITTTDLVSKSIAVQTEIGGVPIKIGGMAKGSGMIHPNMATMLGVLTTDAQVSSDVWREMVRTSVSRSFNQITVDGDTSTNDCVIALASGLSGLSSILTHDSTEAQQFQACLDAVMQGLAKSIAWDGEGATCLIEVTVAGANNEAEAAKIARSVASSSLVKAAVFGRDPNWGRIACSVGYSGIQFDADQLDISLGAIPLMKNGQPLPFDRSAASKYLKDAGDIHGTVNIDVSVGRGGGSGKAWGCDLSYKYVEINAEYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DEF_SALRD
Sequence: MILPIYVYGHEALRNETDPVQENTEALQELIDNMIETMHNAAGIGLAAPQVGRTERLFVVDLTPMADEIAEAGEPLPPQPMVFINPEIVEESEDTAEMEEGCLSIPEVREAVARPERIRMRYRDREFEEQELEAGGMLSRVLQHERDHLDGVLFTDYLSSFRKRLLRRPLREMVNGEVEADYPLVTKDDETVPSR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PFD6_HUMAN
Sequence: MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
What are the official names of this protein?
Prefoldin subunit 6, Protein Ke2.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: NCPP_SALPK
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVGNARRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSQYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: BMRR_BACSU
Sequence: MKESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKYIGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPALGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTSIDEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIAE
What is the function of this protein?
Activates transcription of the bmr gene in response to structurally dissimilar drugs.  Binds rhodamine as an inducer.
What are the official names of this protein?
Multidrug-efflux transporter 1 regulator.
Protein: LEPA_BRUA1
Sequence: MSTPLDHIRNFSIVAHIDHGKSTLADRLIQLTGGLDTREMKDQVLDSMDIERERGITIKAQTVRLSYKAKNGEDYVLNLIDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQAIDNNHEIVVVLNKIDLPAAEPERVKQQIEEVIGIDASDAVEISAKTGLGIEDVLEAIVNKLPAPKEGDRNAPLKAMLVDSWYDSYLGVIVLVRVIDGVLKKGQTIRMMGTGAKYPVERTGVFTPKMVQVDDLGPGELGFITASIKEVADTRVGDTITEDRRPTENILSGFKPAQPVVFCGLFPVDAADFEDLRGAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLITTAPSVVYRLNMTDGTHKELHNPADMPDVVKIASIEEPWIKATIMTPDDYLGAIMKLCQERRGIQIDLTYVGPRAMITYDLPLNEVVFDFYDRLKSISKGYASFDYNLSDYREGDLVKMSILVNEEPVDALSMLVHRSAAEKRGRALCEKLKELIPQHMFKIPIQAAIGGRIVARETISALRKDVTAKCYGGDVTRKRKLLEKQKESKKRMRQFGKVEIPQEAFIQALKMGDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL14_ALISL
Sequence: MIQMQSTLDAADNSGARKVMCIKVLGGSHRRYAHIGDVIKVTVKEAIPRGKVKKGDVLKAVVVRTRKGVRRPDGSIIRFDRNACVLLNDTTEQPVGTRIFGPVTRELRNAKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y574_MYCA1
Sequence: MAGNSRRRGAVRKAGTKKGPTVGSGGQRRRGLEGRGPTPPAHLRPNHPAAKRAQSPPRRPAKRTEETETVLGRNPVLECLRAGVPATALYVALGTEADERLTESVSRAADSGISILEVPRADLDRMTGNHLHQGIALQVPPYIYAHPDDLLEAAAGSPPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRTLQDWADRGLRVIGLDAGGDTTLDDLDGSDPLVVVVGSEGKGLSRLVRQNCDEVVSIPMAGSAESLNASVAAGVVLAEISRQRRG
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase MAV_0574.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: TWHH_PSEPR
Sequence: NSLAISVMNQWPGVKLRVTEGWDEDGHHSKESLHYEGRAVDITTSDRDKSKYG
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes (By similarity).
What are the official names of this protein?
Tiggy-winkle hedgehog protein.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Tiggy-winkle hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. The N- terminal peptide remains associated with the cell surface. Tiggy-winkle hedgehog protein C-product: Secreted, extracellular space. The C- terminal peptide diffuses from the cell.
Protein: RUVA_SHISS
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARTDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: BETA_ACIAD
Sequence: MTTQTFDYIIIGAGSAGNVLAARLTEDADVSVLLLEAGGPDYRLDFRTQMPAALAYPLQGRRYNWAYLTEPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDLEGWSKLKGLENWTYADCLPYYKKAETRDIGGNDYHGDHGPVSVATPKDNNNVLFHAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTKNGRRSSTARGYLDMAKERPNLTIITHAMTNKILFNGKQAIGVEYIQGADKRDLKKVMANKEVLLCAGAIASPQILQRSGVGESTFLKSMDIDVVHDLPGVGENLQDHLEMYLQYKCKQPVSLYPALKWYNQPAIGAEWLFLGKGIGASNQFEAGGFIRSSDEFEWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRSPSRGHIKLKSKDPFEHPSILFNYMSTEQDWQEFRAAIRITREIMHQPALDPYRGEEISPGKQLSTDTQLDDFVRNHAETAYHPSCSCKMGEDDMAVVDHQGRVHGLQGLRVVDASIMPLIITGNLNATTIMMAEKIADQIRERAPLPRSDAPFYVASA
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: Y1398_CORDI
Sequence: MTKDQQNIERGSVINVEILNAAHGGQGIAKYDGRVIFVKGAFPGDRLSANITHVKKKFARATIASIEMPSPLRMQQRCLAAANGAGCCDFGEFDPEIEGRYKADLVLEQLERLGKVSQPPTCEVVSFGSPTQWRTRMRLGVDAQGRAGGFASQSREVVSGVPCSQGVMGLLDGIVGAEQNVLRFTPGSQVVVVCDDLGQRTVVETQPAPRGKRTESMVKVVEGTGKVSQVVDGVTFELPATGFWQSHKDAAQAYADTIREWFGSLIIRNTDSSLVAWDLYGGCGSFASAILSAVDNHGVVHCVESAPAAVSAGKRALSQLVEDQKIVFHTETVERAMNQLPAPTLVVLDPPRVGAGAETVRAIAQSGPQAAIHIGCDPATFARDIAEWSRNGFILEKLRVFDAFPGTHHCETIGLLTKKN
What are the official names of this protein?
Uncharacterized RNA methyltransferase DIP1398.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.