PharMolix/UniProtQA huggingface dataset:
Protein: RPIA_NEIG1
Sequence: MTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSGKKIKGAVSTSKKSGELLARYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADESKYVSRLGKFPLPVEAVESARSLVSRKLLAMGGQPELRIGYTTFYGNQIVDVHGLNIDQPLTMEDEINKITGVLENGIFARDAADVLILGTEEGAKVIYPCQG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MIC12_KLULA
Sequence: MSKLLKLTGFTTLSTLLGVSYYYYVIDRPLYQQTALHKTNVQVENIIDNKAQFQYEHMSRDSQAVVQRPFAETVKDIWNKEVRNTADWLYSWGK
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC12, Altered inheritance of mitochondria protein 5, mitochondrial, Found in mitochondrial proteome protein 51.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic12 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RLMN_ECOHS
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEVDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB45_SCHPO
Sequence: MAETAEKVILLTGSSKGIGLATAEALQKKAKVIAVSRSLTPELETLLIQNPDSFVHVKGDVTEVGKASIETAIKKFGKLDSVILNAGVLEPIAKIADADINEWRKLFDINFFSVVETVKYAIPHLRKTKGTIVIVSSGAAVRVFPAWAAYCCSKAAINMLVMNLGSEEPDIMSVAVRPGVVDTPMQVSIRNDSNKEAMGGDTHNFFKELKTSGQLVAPQDIAKALSFLALNNNPKLTGQFVEWKSFV
What are the official names of this protein?
Uncharacterized oxidoreductase C30D10.05c.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RLP40_ARATH
Sequence: MSELLFSLNFLLLLLLSCVSPSSFFTFNNPVVGLGACGPHQIQAFTQFKNEFDTRACNHSDPWNGVWCDDSTGAVTMLQLRACLSGTLKPNSSLFQFHHLRSLLLPHNNFTSSSISSKFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFARNLRKLRVLDVSYNHFSGILNPNSSLFELHHIIYLNLRYNNFTSSSLPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLPLVQNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEVPNSSSSSRLESLHLGENHFEGKILEPISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKASLTLDSYIPSTLEVLRLEHCDISDFPNVFKTLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLLTGFEGSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAIDNRFGGDIPLSICNRSSLDVLDLSYNNFTGPIPPCLSNLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSVDHNGIKDTFPFSLKALPKLQVLLLSSNKFYGPLSPPNEGPLGFPELRILEIAGNKLTGSLSSDFFVNWKASSHTMNEDLGLYMVYGKVIFGNYHLTYYETIDLRYKGLSMEQRNVLTSSATIDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQGTQITGQPKSSFEGNAGLCGFPLQESCFGTNTPPAQHPKEQEEEEEDEQVLNWKAVAIGYGIGVLLGLAIAQLISLYKPKWLASLVIKSRNC
What are the official names of this protein?
Receptor-like protein 40, AtRLP40.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DPOE_SCHPO
Sequence: MPLKTARGASKYQFRKFNGNYNGKSKSNGRTFAKSTEEVGFNDPMKIVYKKNEIDRMMGFDSYEGGQPREAWLLNVHPTVIESTKGNSTLSAVDFYFIQDDGDTFRCTIPYSPYFYIAAREGKEALVDDYLKKKFVGLIKSTTRIFKEDLQLKNHIVGYQKLYIKLVFDNLNDLQAVRKSLMSAVKANSSQQDAVDAYTNLSSENLNGIIENAFEDPLNHVLDIREYDVPYHSRTLIDLNIRVGQWYTVSYHEGHVQISLLASRIERAEPTIMAFDIETTKLPLKFPDSSFDKIMMISYMIDGQGFLITNREIISQNIEDFHYTPREEFEGPFIIFNEPDEVGLLHRFFKHIRSAKPSVIVTYNGDFFDWPFVDARAAFHGLNLTEETGFFRDAEDEYKSSYCSHMDAFRWVKRDSYLPQGSQGLKAVTVSKLGYNPIELDPELMTPYASEKPQVLAQYSVSDAVATYFLYMKYVHPFIFSLCNIIPLNPDEVLRKGTGTLCETLLTVEACTKNIILPNKHVDASQKFFDGHLLASETYVGGHVESLESGVFRSDLPTNFNMDPKVYEELILQLDKALDFSLTVENNVNVDEIENYEEVRDSILKKLSDLRDRPKRSEKPRIYHLDVASMYPNIMITNRLQPDSVKDESFCATCDLNVPNKTCDRRMVWAWRGEYYPAKKGEYHMIYSALQSERFPGPTPFSPFRSFQELSPSEQAAMVQKRIADYSRKVYHRLYDNTVIERETIICQKENSFYIDTVKSFRDRRYDFKGLQKKWVKQLAAIKEKGGLAEIEEAKKMVVLYDSLQLAHKVILNSFYGYVMRKGSRWYSIEMAGITCLTGATIIQMARQIVERAGRPLELDTDGIWCILPESFPENFEFKKKSGGKVFISYPCVMLNHLVHEKFTNHQYSALKDPEKLVYETTSENSIFFEVDGPYRAMILPASTEEGKNLKKRYAVFNFDGSLAELKGFEVKRRGELKLIKDFQSQIFKVFLKGDSLEECYQEVAYVADTWLEILFTKGSNLTDDELIELISENRSMSKALSEYGSQKSTSITTARRLADFLGDQMTKDKGLACRFIISASPKGRPVAERAVPVAIFFAEESVKRHFLRLWLKDNGLYDVDIRDIIDWDYYLKRLGSVVQKLISIPAALQRISNPVTRFPLPDWLQKRVAVLNSKYQQKKIDSIFSLAPTNPSTINNTKVTDIEDLGSVTHKDKRIVARVTKRKLLQQSGNSEAPVSFEVKPVSFMDGYSNWLKYAKKKWKYQKQVKLRRRHLIGFQSRQFTNVLQSSAEVMFENLWHILQIRETDVPGILHAWVIIRNRLTSIRFIVNRKFFVCFKDETLPNVEIEGCLIEKSNAILPHGSTSDKLFLLEIPEKSYLTEKVSISMIFAHPSVSGIYETRIEPIERLILEMGSRKRFNNSVPGALGKGFEFGFESKMFTDPSDNDVSYLDGVEMNYLYAFHFSISNRFVFSLFMPHLKKVEAIIYDKLPGSDMSFPSISKIYEELRSKFDNLIKESSIEYPDTLSCNVIFSGNERKAYKLIDEKLLQYFSTKTKNSLLIIESSLPHILKANVKQIEELPYIMIPRLESNIQSLSWKQHIATKMIQHFLAIGSWLFHRIQLSRFSDIPLCNFESDDIQYSIDVVYSRKLKEHNIILWWNKGPTPDLGGIEKDSILQIASPKDPLEVNNPGAYSNACVDISLSNLALCSILNSALINDIEGIGDMAALNDNYMTAINDDLEEKLGIHDNIGLTHSLPVLKALVKTWWNEAASGNNLADLIIQHLARWISSSKSYLYSPLLSSHVEVIMRKTFLQLLSEIKRLGAHIIHASANKILIKTSKLIVQNAVTYSNYLLKSIKTLPLFHFLDLNVTEYWDYLLWMDSVNYGGKMVAANFSATNEEPQTVVSWHIKSHLPPIIQPEFQSWIVEFIEEVYKQKLEKSNTKVGFVRVKNNNADEDSEIVGSGILKSKLIHPLKRKVAQVRRCFQELQLDENTREDLKFPKLPGSFLNYTDGALELVKSICAVFELSHDLNLEVRFLKKSLLSLLQIQEFSTQAVFRYPSRRLSLDQIPCKQCGVHQDFDLCLHEHLWPTRDDMGTLVFSDGWSCSSCNLVYDRWVFEETLVDNLYHQLTLYQLQDLICSKCKTVKQWSLKERCSCSGEWVLQLSPTKFREMLNVYQSVADFYEFSILQNSVQSILSVLN
What is the function of this protein?
DNA polymerase II participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISCA_ECOSE
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TLD_DROME
Sequence: MKGMRLMPMKMKAKLVVLSVGALWMMMFFLVDYAEGRRLSQLPESECDFDFKEQPEDFFGILDSSLVPPKEPKDDIYQLKTTRQHSGRRRKQSHKSQNKAALRLPPPFLWTDDAVDVLQHSHSPTLNGQPIQRRRRAVTVRKERTWDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKNGNGRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKCASCGRTYQQNSGHIVSPHFIYSGNGVLSEFEGSGDAGEDPSAESEFDASLTNCEWRITATNGEKVILHLQQLHLMSSDDCTQDYLEIRDGYWHKSPLVRRICGNVSGEVITTQTSRMLLNYVNRNAAKGYRGFKARFEVVCGGDLKLTKDQSIDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDFVEIRDGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHGCQHLCINTLGSYQCGCRAGYELQANGKTCEDACGGVVDATKSNGSLYSPSYPDVYPNSKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTFGSYQCSCRNGYTLAENGHNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVSECGGYLRATNHSQTFYSHPRYGSRPYKRNMYCDWRIQADPESSVKIRFLHFEIEYSERCDYDYLEITEEGYSMNTIHGRFCGKHKPPIIISNSDTLLLRFQTDESNSLRGFAISFMAVDPPEDSVGEDFDAVTPFPGYLKSMYSSETGSDHLLPPSRLI
What is the function of this protein?
Metalloprotease which cleaves TGF-beta family ligands daw, Actbeta and myo in vitro (PubMed:17119021).  Cleavage of daw enhances its signaling activity (PubMed:17119021).  Cleaves dorsal-ventral patterning protein sog (PubMed:15872004).  Processes sog more efficiently than metalloprotease tld which also cleaves sog (PubMed:15872004).  Required for normal dorsal development.  TLD may interact physically with DPP-C protein.
What are the official names of this protein?
Dorsal-ventral patterning protein tolloid.
Protein: XPA_XENLA
Sequence: MEPEPEPEQEANKEEEKILSAAVRAKIERNRQRALMLRQARLACRPYPTGEGISTVKAPPKVIDSGGGFFIEEEEAEEQHVENVVRQPGPVLECDYLICEECGKDFMDSYLSNHFDLAVCDSCRDAEEKHKLITRTEAKQEYLLKDCDIDKREPVLKFILKKNPHNTHWGDMKLYLKAQVIKRSLEVWGSEEALEEAKEVRKDNRDKMKQKKFDKKVKELRRTVRSSLWKKEASGHQHEYGPEEHVEEDSYKKTCITCGYEMNYEKM
What is the function of this protein?
Involved in DNA excision repair.  Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region (By similarity).
What are the official names of this protein?
DNA repair protein complementing XP-A cells homolog, Xeroderma pigmentosum group A-complementing protein homolog.
What is the protein family that this protein belongs to?
Belongs to the XPA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URK_BORRA
Sequence: MVKIIGISGGSGSGKTTIVNKISEVISEFVLISQDNYYKSVGDYEYEFLDVNFDHPDAFDNNLFYKQLKKLKENQSINMPLYDFINHKRRDETIKIVPTPIIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLESVIEQYLRTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLKTLVKDSSKFF
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_BTV10
Sequence: MEEFVIPVFSERDIPYSLLNHYPLAIQIDVKVDDEGGKHNLIKIPESDMIDVPRLSIIEALNYRPKRNDGVVVPRLLDITLRAYDNRKSAKNAKGVEFMTDTKWMKWAIDDKMDIQPLKVTLDNHCSVNHQLFNCIVKARSANADTIYYDYYPLENGAKRCNHTNLDLLRSLTTTEMFHILQGAAYALKTTYELVAHSERENMSESYQVGTQRWIQLRKGTKIGYRGQPYERFISSLVQVIIKGKIPDEIRTEIAELNRIKDEWKNAAYDRTEIRALELCKILSAIGRKMLDVQEEPKDEMALSTRFQFKLDEKFIRTDQEHVNIFKVGGSATDDGRFYALIAIAGTDTQQGRVWRTNPYPCLRGALIAAECELGDVYFTLRQTYKWSLRPEYGQRERPLEDNKYVFARLNLFDTNLAVGDEIIHWRYEVYQPKETTHDDGYICVSQKGDDELLCEVDEDRYKEMFDRMIQGGWDQERFKLHNILTEPNLLTIDFEKDAYLGARSELVFPPYYDKWINSPMFNARLKIARGEIATWKADDPWSNRAVHGYIKTSAESLEYALGPYYDLRLQLFGDTLSLGQRQSAVFEHMAQQDDFSTLTDYTKGRTVCPHSGGTFYTFRKVALIILSNYERLDPSLHEGREHETYMHPAVNDVFRRHVLEMKDFSQLICFVFDYIFEKHVQLRNAKEARRIIYLIQNTSGAYRLDVLREAFPNFLKHVMNLRDVKRICDLNVINFFPLLFLVQDNISYWHRQWSIPMILFDQVIRLIPVEVGAYANRFGLKSFFNFIRFHPGDSKKRQDADDTHKEFGSICFEYYTTTKISQGEIDVPVVTSKLDTLKLHVASLCAGLADSLVYTLPVAHPKKSIVLIIVGDDKLEPQIRSEQIVNKYYYSRRHISGVVSICVNQGGQLKVHSMGITRHRICDKSILKYKCKVVLVRMPGHVFGNDELMTKLLNV
What is the function of this protein?
The VP2 protein is one of the two proteins (with VP5) which constitute the virus particle outer capsid.  It is the major target of the host immunogenic response.  Responsible for viral attachment to target host cell, probably by binding to sialic acid.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Outer capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP2 family.
What are the subcellular locations of this protein?
Virion.
Protein: ASPG_ELIMR
Sequence: MRIIYKQQTMNNNRRDFIKKLGIATAAIAINPLEAKNLLDTSEPKTTNKPIVLSTWNFGLHANVEAWKVLSKGGKALDAVEKGVRLVEDDPTERSVGYGGRPDRDGRVTLDACIMDENYNIGSVACMEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKEWLKTSQYKPIVNIENHDTIGMIALDAQGNLSGACTTSGMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELMNQGRTPQQACKEAVERIVKIVNRRGKNLKDIQVGFIALNKKGEYGAYCIQDGFNFAVHDQKGNRLETPGFALK
What is the function of this protein?
Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.  Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus.
What are the official names of this protein?
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, Aspartylglucosaminidase, AGA, Glycosylasparaginase, N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PK1_STRTO
Sequence: MDTTLQDPLVGQVLDGRYRVDARIAVGGMATVYRAVDTRLDRVLALKVMHPSLAADASFVERFIREAKSVARLAHPNVVQVFDQGTDGAYVYLAMEYIAGCTLRDVLRERGALQPRAALDILEPVLAALGAAHRAGFVHRDMKPENVLIGDDGRVKVADFGLVRAVDSVTNTTGTVLGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEKPHDGDSPAIVLYKHLHDDVPPPSAAVPGMAYELDELVASATARGPEVRPHDAVALLARARDARARLGDEQLDAVPPQALASEHDNADDRTSVIPRALTVRRPLPVNEEDEGADAAHRTSRFRSPPPLPPRGRTALRRGPMAIVIGVLLVLGLGAGVWYINSGQFTKVPPLLAKTEKEARDRLADAGLDAGQVSEAYSDTVERGSVATDPEAGARIRTNDSVSLTLSKGPRTVRVPDLDGYPQDKARSLLEDEGLKPGMSTREFSDSVPAGSVISTEPGKGTEVRAGSAVALTVSKGAPVDVPDVAGDDLEDARAELEEAGLEVKVATERVTSEYDAGRVARQDPGPGGRVAEGDTVTLTLSKGPEMAEVPDVVGDSVGEAREKLEGAGFRVDEDRGLLGLFGDTVKGQSVDGGDSAPKGSTITIEIR
What are the official names of this protein?
Serine/threonine-protein kinase PK-1, stoPK-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RLMM_ECO27
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSSNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_CLOTE
Sequence: MFKDVVEEFKKFAIKGNAIDLAVGVVIGGAFGKIVTSLVQDIIMPAVGLLLGKVNFKTLSLTVTSIDGSEIVLKYGQFIQSVVDFIIISFSIFLFVKLINSFKKKEEEKPKVEEPSKEEKLLAEIRDILKESK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_PHEZH
Sequence: MAEITAALVKELREKTDAGMMDCKKALQENNGDLEAAADWLRTKGLSKAAKKSDRAAAEGLVAGLVSADGKSGVLIELNAETDFVAKNEKFQDAARRIAATALVHEALETLHEAKTAEGEVVNDLVTGLIATIGENMRLRRSERLRVENGAVALYLHNVQGEGVARLGVLVALEGAGDQAVLKDVGRKIAMHVAGTPTPPLALNSSDLDPEAVAKEREIQTQTAMESGKPREIAEKMVEGRIRKWQEEVVLLKQPFVMNPDQTIEELIAETAKQAGGPVSVKGFVRFALGEGVEKKQDDFAAEVASMTSAS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG16_KLULA
Sequence: MELPLLDKLKVRDLVDKRFSHLFETVSLLSGDNEEDNEDQLRLKNSIKNLREHLTEKEEEIRQLHDVISVKNRDAERLNDELISINIENNLLQERLTHIQAEYDTLIERWLLKAQREADIMNTRLK
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy.  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS).  Recruits also ATG3 to the PAS.  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).
What are the official names of this protein?
Autophagy protein 16.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: AG10B_HUMAN
Sequence: MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKKEDRLPPIKGPFAEFRKILQFLLAYSMSFKNLSMLFCLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYAILKYLLVPAYIFAGWSIADSLKSKPIFWNLMFFICLFIVIVPQKLLEFRYFILPYVIYRLNITLPPTSRLVCELSCYAIVNFITFYIFLNKTFQWPNSQDIQRFMW
What is the function of this protein?
Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity).  When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 (PubMed:14525949).  Has a role in maintenance of cochlear outer hair cell function (By similarity).
What are the official names of this protein?
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-B, Asparagine-linked glycosylation protein 10 homolog B, Potassium channel regulator 1.
What is the protein family that this protein belongs to?
Belongs to the ALG10 glucosyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_ACTP2
Sequence: MGPTASGKTDLAIALRQTLPVEVISVDSALIYKGMDIGTAKPSKAELELAPHRLIDILDPSESYSAMNFREDALREMAEITASGRIPLLAGGTMLYYKALLEGLSPLPSADPEIRAEIEAKAEQIGWSGLHRELLAIDPIAGKRINPNDSQRINRALEVFYITGKTMTELTAQQGDSLPYNVLQFAIAPQDRAVLHQRIEQRFYKMMELGFQQEVEKLRARSDLHKDLPSIRCVGYRQMWEYLDGDISLDEAIYKGICATRQLAKRQITWLRGWNSEITWLDSLDPTSSKLKMIEKIAQNSIKL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRMD_ECOL6
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_YERE8
Sequence: MFTGSIVALITPMDDKGNVDRASLKKLIDYHVASGTAAIVSVGTTGESATLNHDEHVDVVLQTLELADGRIPVIAGTGANATSEAISLTQRFNDTGVVGCLTVTPYYNRPMQEGLYQHFKAIAESTDLPQILYNVPSRTGCDMLPPTIARLAKIKNIVAVKEATGNLSRVSQIQVLVDDEDFILLSGDDASGLDFMQLGGQGVISVTANIAAREMVELCALAAQGNFAEARRLNQRLMPLHQHLFVEANPIPVKWAAKKLGLMANDTLRLPMTPLTDPAKRVVEDALKSAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_NOCFA
Sequence: MKLAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREHDAILLGAIGDPSVPSGVLERGLLLRTRFELDHHVNLRPSRLFTGVRSPLAGAPDIDFVVVREGTEGPYTGTGGAIRVRTPHEVATEVSTNTRFGIERVVRYAFAKAQARRKHLTLVHKTNVLTFAGSLWQRTVDEVGAEFPEVTVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLAAAVSGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQSKADPTAAILSVSLLLNHLGDTEAAARIDAAVAKDLAARSGTASTVEIGDRIAAAV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_RHIE6
Sequence: MIPGEIIAASGDIELNAGAPTVTLEVSNTGDRPVQVGSHYHFAETNAGLSFDRAAAHGKRLDIPSGTAVRFEPGQTRSVTLIPLAGKREVYGFRQLVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDC1_XENLA
Sequence: MTMLGERLVLRWRVAASFAWSVILMPVCCALFIVLSRIQILHPIQWLTDSISDLTSSYTIFCLLLICAILGLQCTFLMEYYTVVPSIPCSRLALIGNLLLPHRILHSLAHVAMGVLASWCYAVLSKGKYQLLVVSCTLQSEDEADKPSHCLNESHLFQLLCGAFFGYSYSLQYFVHNMNYLSFPSIQQYKYLQFRRFLPLIIKQSVFQSLYFIRSYAILYFCLGNIPRTWIQTALNLHMDRQQPSLDTLRGFLNLSLFYQIWLSGTFLLATWYMVWILFRIYTTEARIFPVQTSFAEEAEKCLPFILNSNTLPLVKYLAMQDLVLLSQYSPSRRQEVFSLSQPGGHPHNWTSISKECLNLMSSLTSRLIAHQEAAANNGRMRVPSSPKQIRKSSSSSGTSLIEDSAEQTQNLSTIPRIGIPSLLKTASLKSSLDIGSPFATPGVKQMSESLDPNTPCHGSVQSPQVTRRGAKLWTSDSDVQKNGSEVSPVMHRPVCNGAKQGILHTWFQHKLVQIKNVLSKRGLIMYLFSKHPEASSQDVFADAQIHIWALEALSHLVAASFSEDRMGVVQTSLSSVLAILLTLQEAVEKHFKLPHASSKPARNPGSLLDSSCKTLRFSLRAALKTAIYRITTTFGEHLHAVPVSSEHKKKLQQFLDFKE
What is the function of this protein?
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope.  Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
What are the official names of this protein?
Nucleoporin NDC1, xNDC1, Transmembrane protein 48.
What is the protein family that this protein belongs to?
Belongs to the NDC1 family.
Protein: RL3_ACIBC
Sequence: MHMAIGLVGRKCGMTRIFTDAGVSVPVTVIEVDPNRITQIKTLETDGYQAVQVTTGERRESRVTNAQKGHFAKAGVAAGRLVKEFRVTEAELEGREVGGTIGVDLFTVGQIVDVTGQSKGKGFQGGVKRWNFRTQDATHGNSVSHRVLGSTGQNQTPGRVFKGKKMAGHLGDERVTVQGLEIVSVDTERSVLVVKGAIPGATGGDVIVRPTIKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.