PharMolix/UniProtQA huggingface dataset:
Protein: NU4LC_SOLTU
Sequence: MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDNRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NTPP_ACAM1
Sequence: MTIPFILASASPARRQLLKTVGIDPVVLPSHFDESQVTTTDPEALVTTLATGKAEVVAHQQQPPALVLGCDSVLELGGEIYGKPQGIEDAISRWKTMRGQTGRLLTGHTLIDLKQNHQLIRCQITEVDFAPLTDNQIRAYAETGEPLHCAGCFALDGRGGLFVEQIRGCHSNVIGLSLPLLRQMITELGYDVTDLWSNESP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KADA_METVO
Sequence: MKNKVVVVTGVPGVGSTTSSQLAMDNLRKEGVNYKMVSFGSVMFEVAKEENLVSDRDQMRKMDPETQKRIQKMAGRKIAEMAKESPVAVDTHSTVSTPKGYLPGLPSWVLNELNPDLIIVVETTGDEILMRRMSDETRVRDLDTASTIEQHQFMNRCAAMSYGVLTGATVKIVQNRNGLLDQAVEELTNVLR
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_BACP2
Sequence: MAKVYVFDHPLIQHKLTYIRDVHTGTKEFRELVDEVATLMAFEITRDLPLEEVDVETPVQVAKSNVISGKKLGVVPILRAGLGMVDGILKLIPAAKVGHVGLYRDPKTLKPVEYYVKLPSDVEEREFIVVDPMLATGGSAVEALNSLKKRGAKNIRFMCLIAAPEGVEEMQKHHPDVDIYIAALDEKLNEKGYIIPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: 4CL_PINTA
Sequence: MANGIKKVEHLYRSKLPDIEISDHLPLHSYCFERVAEFADRPCLIDGATDRTYCFSEVELISRKVAAGLAKLGLQQGQVVMLLLPNCIEFAFVFMGASVRGAIVTTANPFYKPGEIAKQAKAAGARIIVTLAAYVEKLADLQSHDVLVITIDDAPKEGCQHISVLTEADETQCPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVSSVAQQVDGENPNLYFHSDDVILCVLPLFHIYSLNSVLLCALRAGAATLIMQKFNLTTCLELIQKYKVTVAPIVPPIVLDITKSPIVSQYDVSSVRIIMSGAAPLGKELEDALRERFPKAIFGQGYGMTEAGPVLAMNLAFAKNPFPVKSGSCGTVVRNAQIKILDTETGESLPHNQAGEICIRGPEIMKGYINDPESTAATIDEEGWLHTGDVEYIDDDEEIFIVDRVKEIIKYKGFQVAPAELEALLVAHPSIADAAVVPQKHEEAGEVPVAFVVKSSEISEQEIKEFVAKQVIFYKKIHRVYFVDAIPKSPSGKILRKDLRSRLAAK
What is the function of this protein?
Carboxylate--CoA ligase that may use 4-coumarate as substrate.  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.
What are the official names of this protein?
4-coumarate--CoA ligase, 4CL, 4-coumaroyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ILVD_ECOLC
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDRIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CCME_RHOPS
Sequence: MTRKQRRLLMIGGAGVVLVVAVGLVLNAMRGSIVFFSTPKMVSEQQIGAGTRFRLGGVVEPGSLHRGDQLAVSFKVSDGAATVPVAFKGILPDLFREGQGVIAEGALDTAGVFKADTVLAKHDETYMPKEVADALKKQGHWKDDYEKKPPGAPGASADAAGPSR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: 2A5E_ARATH
Sequence: MFNKIIKLGQKKFNKSDQHHQDNNNNNNNTSTNTVVRGSRTTTPAPSSVSNGESQTTAQSPSQTPNHPMFTTTPILEVLPLLKDVSSSDRPLLFMKKAHMCSCHCDFSDTLIMPREKEIKRQTLLELVDFLHSSSGKVNETMQSELIRMVSANIFRCLPPAYHENTGAPPEGNDPEEEEPYLEPWWPHLQLVYELLLRYVVSSEIEPKTAKKFINHTFVSRLLDLFDSEDPREREYLKTVLHRIYGKFIFHRPFIRCSIYNIFYKFLYETERCIGIGELLEILGSVINGFTVPMREEHRLYLVKAILPLHKSKGISIYHQQLAYCVTQFVEKDYKLADTVIRGLLKFWPLTNCQKEVLFLGELEEVLDATEPSEFQQCVVPLFTQIGKCLNSAHFQVAERALFLWNNEHIVGLIAQNKDVIFPIIFEALERNMKGHWNQAVHGLSENVRRMFLEMDTELFEECEKQYLENEAKACELLEQRELTWKRLEEAASLAAN
What is the function of this protein?
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' epsilon isoform, AtB' epsilon, PP2A, B' subunit, epsilon isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAG51_CAEEL
Sequence: MDSAESELLEEEELPEIKYIDSAEFQNFDNNADQREIQFRWMEAFETKEPRWFRLLDEFITPLSGKRGYCSRIVEKYARVLLHQGFELSQTDGPLRVAAIAASRDVGQAGNLPSVLNNLSEVTRHLNLAQYASTSLATVGQRKFANEVVQKTVNQERLGCFHLFLIGYREGLENLLSNHRHLRNFRYSAKKRHDLLTEHIKNIFQERDSFIQAPEASSFALQTVLENWTFPLQNEQIVQLAHANTLQMRALHVKGDGFYFLNEALNVAIAFNWSSSQEEMEEFYSIFTPQATNPRGKRIFQFWKMISKYDRSNGNAQGFLVTAQRLEEESKSDDIGAGCVTAVELACKIRNQCDQHEDLSKTIMDTITRHPSLGPRMMQLAERCGVGYENEEIIHQICDRFSLHPSEPTWLDYVENLVQTVGRFGSVKETMQKSLKIMFEFLDFDSNRFNERAWSLFEKVLSLTDPSFVVPEWRTRFDWWPKYQRLRAKDGRKMSNMATKTRNDVLEALEELVL
What are the official names of this protein?
Uncharacterized protein tag-51.
Protein: COX1_SEPOF
Sequence: IGTLYFIFGIWSGLLGTSLSLMIRTELGKPGSLLNDDQLYNVVVTAHGFVMIFFLVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSLTLLLASSAVESGAGTGWTVYPPLSSNISHAGPSVDLAIFSLHLAGVSSILGAINFITTIMNMRWEGLQMERLPLFVWSVFITAILLLLSLPVLAGAITMLLTDRNFNTTFFDPSGGGDPILYQHLFWF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPE_THET8
Sequence: MERIRPYRKTFLADLETPVTAYLKLAEKAPVSFLLESVERGRQSRFSIVGVGARRTFRLKDGVFTVNGERVETRDPLRALYERVYAPLERHPDLPPFFGGVVGYAAYDLVRYYERLPSLKPDDLGLPDLLFVEPEVVAVFDHLKNLLHLVAPGRDPEEAEARLFWAERRLKGPLPGVPGERAGGRARFQADFSREAYLEAVRRALDYIRAGDIFQVVLSLRLSSPLTVHPFALYRALRSVNPSPYMGYLDLGEVVLVSASPESLLRSDGRRVVTRPIAGTRPRGKDEEEDKRLAEELLRDEKEVAEHVMLLDLSRNDIGRVAAFGTVRVLEPLHVEHYSHVMHLVSTVEGILAEGKTPLDALASVLPMGTVSGAPKIRAMEIIEELEPHRRGPYGGSFGYLAYDGAMDMALTLRTFVVAKGWMHVQAGAGIVADSVPEREYEECWNKARALLKAVEMAEAGL
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: VF385_ASFP4
Sequence: MDEIINKYQAVEKLFKEIQEGLAMYDQYKTLINELLHYNNHIKQEYFNFLMIISPYLIRAHSGETLRNKVNNEIKRLILVENINTKISKTLVSVNFLLQKKLSTDGVKTKNMWCTNNPMLQVKTAHNLFKQLCDTQSKTQWVQTLKYKECKYCHTDMVFNTTQFGLQCPNCGCIQELMGTIFDETHFYNHDGQKAKSGIFNPNRHYRFWIEHILGRNSEQELGTKQDPCGTKVLQQLKKIIKRDNKCIALLTVENIRKMLKEINRTDLNNCVSLILRKLTGVGPPQISESILLRGEYIFTEAIKIREKVCKKGRINRNYYPYYIYKIFDAILPPNDTTNRRILQYIHLQGNDTLANNDSEWESICMELPEIKWKPTDRTHCVHFF
What are the official names of this protein?
Zinc finger protein B385R, pB385R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B385R family.
Protein: RL22_CAMJJ
Sequence: MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAAAVLKRFRPRARGSASRIRKPTSHILVEVAKAEVKAEEKKTVAKKAPAAKKTTTTKAPAKKTTSTKKATAKKES
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RS15_METTH
Sequence: MMSLKPDWVEYSNEEIEDLIVKLYREGNSTSKIGIILRDQHGIPSVKAVTGLKITQILEKHEMKPEYPEDLMNLIRKAVNIRDHLKEHPKDLHTRRGLQIVESKIRRLVRYYVREGVLPEGWRYDPQKAALLVK
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MYT2_MYTCA
Sequence: MFKQSYQLCLVFLLFVCFYQSVKGNYGKRSKYQKHKGTIPYYSNRYHHARRQTALSRTGKSDSSPFQIILRAINRRPGPQINGRGKKSVTRTLGMLQSVLSQRRGLYNHRSQKSQNVFGVLQNLLKNVRMFKRNIGRLYVSDIVRRRIPTVNAQATARVNVQATAGVNSLTTAVNTDSQTRTLNTLRATGWFKEVSENRLIMQQVLRASLNGVIAGWIETLARRDLMEEFIDYPQAFAIITNTVLSSSQKQLILDLGGNDQLQELLENVPAFTLILNYVQTQDRVQMIVTISETGNMDKLISNLGVLNRFLSNAITPGQTAAIRNLAENGQLEQFIDNQRG
What are the official names of this protein?
Mytilin-2, Mytilus uncharacterized protein 2, MUSP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: ZCH12_RAT
Sequence: MASILSRMGNSRGQNSPLPPWAHSMLRSLGRSLGPLMASMAERNMKLFSGRAEPAQGEETFENWLSQVTAVLPDWHMPEEEKVRRLMRTLRGPAREVMRLLQAANPCLDVEDFLRAMKLVFGESESSVTAHSKFVNTVQEPGEKPSLYVIRLEVQLQNAIQAGVFAEREANQARLHQLLVGAEMSTDLRFRLKSLLRVYANEPERLPNFLELIRMIREEEEWEEAFIHPKRPRRSQSVERALSPTFQSSPPVMISSIDCNVIEIDDSPDDSDEDVILVEPDDPPLPSSSAGPSFLGRAVSEDQVLVIESPNIFEIQAPSTSSGAGRKNNNNFGELRRARKRKHTVHCSHCGEEGHSKETCDNESDRGQVFENLIITLQELTHTEERAREIFGEAIGLSELH
What is the function of this protein?
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway.  It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex.  It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 12.
What is the protein family that this protein belongs to?
Belongs to the ZCCHC12 family.
Protein: MAC1_CANAL
Sequence: MILIDDIKYACMECVRGHRSSSCKHHERPLLQVRSKGRPGVYANGNPNHRVAIFAEEIAKSDKPSTNGTKRCKSEPIIVLKASSKQVIDCSSGVIIGPYDETKTKPSTVEKRTPSPPIISDESFINTSACCTPKISKGKSCGCCNNKRKAVNKSKILQNYIKNKLNQKINNNETLVFMNKSHTTNNEQKEDHQLYGMVPVPSCSIPGTCCCDDACSCQGCVVHGNSKYQIPLPTSKQQVTDTTNPFENEEKFIFNSMPQTDKSDLFFNTISTSSNVPPADSSSECSCPPNACDCTNCETHGILNGFRLDDYFKDQSKLMNVLDFNFSELLGTIPEQPIPTEFMQPPSENTLLTSLSSENSFIPNQTKELSTQPPILPLDAQNVCNELDQLEPLVPSLQPCDKKATKWVNNRDTLEDVSDNRVKSCCSKKTK
What is the function of this protein?
Copper ion-sensing transcription factor which activates transcription of the CTR1 copper transporter under low-copper conditions.  Promotes filamentous and invasive growth.
What are the official names of this protein?
Metal-binding activator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROC_METTP
Sequence: MMSGSTFGTLFRVTTWGESHGRAIGVVVDGCPAGIELSEMDVQRELDRRRPGQSTATTERHEADSVEILSGIFEGITTGTPISMLVWNRDARSSHYDSIRHTPRPGHADYTYHVKYGIRDHRGGGRASARETVGRVAAGAVARKLLSEFGVEIAGYVSELGGISASLPRWTSRGSIEREELLDIRERAESSPIRCPDAAASSRMLSLLDSVRSDGDSIGGVVEVIAIGVPPGLGEPVFDKLDADLAKALMSIGAVKAVEIGAGFESARLRGSEMNDPLFYENGRISFERNNAGGILGGISTGAPILCRMAVKPTPSIARSQRTVDMVSGESVDISVRGRHDPSIPPRIVPVAEAMVALVLADHILRQRSARLR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SYA_HELPJ
Sequence: MDIRNEFLQFFQNKGHEIYPSMPLVPNDATLLFTNAGMVQFKDIFTGIVPRPSIPRAASSQLCMRAGGKHNDLENVGYTARHHTLFEMLGNFSFGDYFKEEAILFAWEFVTKNLGFKPKDLYISVHEKDDEAVKLWEKFVPVDRIKKMGDKDNFWQMGDSGPCGPCSEIYIDQGEKHFKGSEDYFGGEGDRFLEIWNLVFMQYERSNDGVLSPLPKPSIDTGMGLERVQALLEHKLNNFDSSLFAPLMEEISELTGLDYASEFQPSFRVVADHARAVAFLLAQEVHFNKEGRGYVLRRILRRALRHGYLMGLKEAFLYKVVGVVCEQFSNVHAYLKESKEMVMKECFEEEERFLETLESGMELFNLSLTHLNENKIFDGKIAFKLYDTFGFPLDLTNDMLRSHGACVDMQGFENCMQEQVKRSKASWKGKQNNADFSAILNAYAPNEFVGYETTECLANALGFFDSDFKEITEANPNQEVWVLLEKTPFYAEGGGAIGDRGTLFKDNEEAALVLDTKNFFGLNFSLLEIKKALKKGDQVIAQVSDERLEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALNDEELEKVEDLVNAQIFKHLTSQVEHMPLNQAKDKGALALFSEKYAENVRVVSFKEASIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLTKEENKELKNAKTLLKNNDVIAGINKLKESVKNSQKAPVSMDLPVEKIHGVNLVVGVVEQGDIKEMIDRLKSKHEKLLAIVFKKENERITLACGVKNVPIKANAWANEVAQILGGKGGGRDDFASAGGKDIENLQAALNLAKNTALKALEG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_HYAHY
Sequence: MTNIRKSHPLIKIVNESFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHAGRGMYYGSYTFSETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAIIHLLFLHETGSNNPSGMTSDTDKIPFHPYYTIKDILGLLLLILMLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAVVPLLHTSKQRGMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASIMYFSIILILMPISGIIENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PA2HB_AGKPC
Sequence: SVLELGKMILQETGKNAITSYGSYGCNCGWGHRGQPKDATDRCCFVHKCCYKKLTDCNHKTDRYSYSWKNKAIICEEKNPCLKEMCECDKAVAICLRENLDTYNKKYKAYFKLKCKKPDTC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity (PubMed:28633930).  Is myotoxic and displays edema-inducing activities (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog APC-K49, svPLA2 homolog, ApcP2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAE_HAEDU
Sequence: MQQSVIEVQQAPFDQHAIYQWLSEPHSVGATTIFVGKVREMNLGDNVSGLYLEHYPAMTKKALQEIVNQARQRWELQRIAVIHRIGQLHTGDEIVLVGVSSAHRGDAYLANEFIMDYLKTKAPFWKRETTAEGERWIESRESDEQQLEKWR
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: MURG_GEOSW
Sequence: MNKKIILTGGGTAGHVMVNLALIPKLKEQGWDIAYIGSHQGIERELISKVEGVPYFPISTGKLRRYFDWNNFKDPFKVLKGTFQAYRIIKKEKPSIVFSKGGFVSVPVIIGAWLNGVPSIIHESDITPGLANKIAMPFATKICVTFPETLRHVKEEKGIYIGAVVREELKRGNADKGRTLCQFEKGKPVLLVMGGSLGSKRINDALRANLQTLLDDFQIVHICGKGNVDPQWTNKKGYKQFEYVHEELPHLMAMADIVLSRAGANSIFEFLALRKPMLLIPLSKEASRGDQILNARSFEKSGYAEVLMEENLTNESLRNAIYHLYQNKDRYRQNMDRSDAGDALQKLLTLIEEARKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROE_THEAC
Sequence: MNGNSIIGLIGHPVSHSIGQILYNRIFQDMGIDAFYLAMDVHMNVLPAFLKNSFFLKAFNVTIPHKVSIIPFLDDLDEIASQTRSVNLVIREQSRMKGYNTDYYGLDYALSFNQVEIEEKRIVIAGSGGIARTVIRYMLDHGAHRVDVLTRNAQNARRNLDIPGIGLHENIDEDYDIYVNCTPLGTLGDGDPFSTVDFRSGRTGIDLVYNPPDTPFLKRMRNAGGRTVSGLDVFIGQGLRTLELVFGIRPDSIFREYAVEALNEIRKG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GOSR2_CAEBR
Sequence: MEAQYQSTNFLLQKVQHDLGRLEGTQNEQDAQVVVQSIYGDISTLKDNLQALDNYVSREQPARRQAARMRVDQLRMDVQRVDMAVSAVHTRMTQRWRSASEREELLSARYRPNDTALSIGDHELQLNDRLHSSHNRLDELISQGSAVLDNLKSQHFSLRGVSRKMHDIGQALGLSNSTLQVIDRRVREDWIFVIGCIVCCIFMYAFYRFWRG
What is the function of this protein?
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
What are the official names of this protein?
Golgi SNAP receptor complex member 2 homolog memb-1.
What is the protein family that this protein belongs to?
Belongs to the GOSR2 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein. Golgi apparatus membrane. Endoplasmic reticulum membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus.
Protein: DCD_YERPB
Sequence: MRLCDRDIEAWLDSGKLGIEPRPPVERINGATVDVRLGNQFRVFRGHTAAFIDLSGPKDEVSAALERVMSDEINLPEGEAFFLHPGELALAVTLESVTIPDDLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGRIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNSRQDAKYRGQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.