PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_SULIA
Sequence: MNIILKISGKFFDEDNVNNLIVLRESIRELTYNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRVYTDVKLIPHLTTQDLRKILEGSQSVQAGTYELLDPLAIKIVERSKIRVVVMNYRKLNRIINILKGEEVSSIIEPT
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMP23_PIG
Sequence: METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLKEIRGNFDITCNQLQSVRIIDLLWRVRRPQKPKFVTVWVR
What is the function of this protein?
Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar.  Its activity appears to be mediated by its ability to damage bacterial membranes.
What are the official names of this protein?
Antibacterial peptide PMAP-23, Myeloid antibacterial peptide 23.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_MARMS
Sequence: MSNKTKLIQQIEAEQMTKEVPAFGPGDTIVVQVKVKEGSRERLQAYEGIVISKRNRGLNSAFTVRKISSGIGVERAFQTYSPLVESIEVKRRGDVRQAKIYYLRERSGKSARIKEKLAKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PNP_CHLCV
Sequence: MTFETIFVTLEEGKTLVFETGKIARQANGAVLARMQETWVFSSVCAANLEEPVDFLPLRVDYQEKFSSIGKTLGGFIKREGRPTEREILTSRLIDRSMRPSLPNRLMQDVQVLSYVWSYDGVTLPDPIAICGVSAALAISDIPQISVVAGVRVGFVNNSWVVNPTKAEMDVSRMELVLAGTENAILMIEGHCDFLTEEQVIEAIEFGHKHIATICRAIKDLQQKVGKKKNSDAIVPLPEEVQSSVNTFVEGKFADLLKIKEKKAFEAASKQLEKEIVEKFLEENEIFTALNIKTAFKQAKSDYMRALIREQSVRSDGRAITTIRPISIDTSFLPRTHGSCLFTRGETQTVAVCTLGSEAMAQRYEDLNGEGLAKFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHTLPDPAKFPYTIRIESNITESNGSSSMASVCGGCLALMDAGVPIKTPIAGIAMGLILDNDHVTILSDISGLEDYLGDMDFKVAGNTEGITAFQMDIKVEGITPTIMQAALAQAKAGRQHILDIMKEALAAPKTDLSQYAPRIETMQIKPNKIATVIGPGGKQIRQIIEEAGVQIDINDSGLVSISASSPQAIEKAKSMIEGLVGEVEVGKIYEGRVTSIVPFGAFVEILPGKEGLCHISEFSKQRIENVGDFVKQGDILAVKLLSINEKGQYKLSHKATLSE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_THIDA
Sequence: MPKDFPRARRVADQIQRELPELIRQEVKDPRVGMLTITEVEVNRDMEFAKVYFTTMGGEAEHAACLQGLQRASGFLRSQLSHRMQLRVVPKLTFVYDRSVEHGMALSRLIETAVAEDAKHPKDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_TOLAT
Sequence: MATLDVLRFPDERLRKIATPIEKITSDLEHIIEDMFETMYLEEGIGLAATQVNIHKRLVVVDTSENRDQPMVFINPELIEKRGETGIEEGCLSVPECRAFVPRAEWIKVRALDRHGEPFEIEADGLLAICLQHEMDHLVGKLFVDYLSPLKRQRIRQKLEKLARNER
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FLIU_SALMU
Sequence: MKEITVTEPAFVTHFSCSGSACSDHCCKGWKITLDKTTVKKYLASKDATIRTIAQDNIILLKKNNSHWGEIKLPSALGNCPYLDEDRLCRVQKTLGAKALSHTCSSFPRAHHTYKNEVRNSLSLACPEVTSRILNDPDAMALGEKKSFSRHSILRRYFQRSKSYSICFA
What is the function of this protein?
Required for the secretion of flagellin and expression of motility.
What are the official names of this protein?
Flagellar biosynthetic protein FliU.
What is the protein family that this protein belongs to?
Belongs to the FliB family.
Protein: RL14_EHRRW
Sequence: MIQKNTLLDVADNSGARKVLCIGLLNGKKSASVGDVIVVSTKVVIPRGKVSKGKVYKAVIVRVKKAVRRLDGSVIKFSSNAVVLINDQGDPLGTRVFGPVKKLPFGLFSKVMSLAVEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CCA_BACC1
Sequence: MKRFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGEMVDLFAGQEAIQKREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKALKELVETKLFSHLPYLQMSEERLLKATQYNWDSFETDIEAWAFFLYCIGEEHPAVFLRQWKFSNKKIKDIVAVLLTVRKRKEKDWDTVLLYKTGIHIAEMAERVYEAMIESYDHTSVKRVQTLFQALPIKNRQEMNVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: URE1_CERS5
Sequence: MPASISRSTYAAMFGPTTGDRLRLGDTDLIIEVERDLTTYGEEVKFGGGKVIRDGMGQSQRTRADGAMDTVITNALILDWSGIYKADVGLRDGRIAKIGKAGNPDTQPGVDIVIGPGTEIIAGEGRILTAGGMDAHIHFICPQQIEDSLHSGITTMLGGGTGPAHGTLATTCTPGPWHIGRMLQAADAFPINLAFAGKGNASLPAGLEEQVRAGASCLKLHEDWGTTPAAIDCCLTVADAMDVQVMIHTDTLNESGFVENTLAAIGGRTIHAFHTEGAGGGHAPDIIKVVGAANVIPSSTNPTMPYTANTVEEHLDMLMVCHHLDRSIPEDVAFAESRIRKETIAAEDILHDMGAFSVISSDSQAMGRVGEVITRTWQTAHKMKVQRGRLAEETGANDNMRVRRYIAKYTINPAIAHGLSHHIGSVEEGKRADLVLWTPAFFGAKPDMVLLGGMIVCAQMGDPNGSIPAQPFYSRPMFGAFGGALHASAVTFVSQAAQADGVGERLRLQKGTLAVEGTRGIGKADMKLNAHRPAIEVNPETYEVRADGEILTCQPLAELPLAQRYFLY
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PC_STAAN
Sequence: MTQITEKELKKKYLDLLSQNFDTPEKLATEIINLESILELPKGTEHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKERLSTKELNDLTALVYYPEDKLKLIKSDFQSCGQLNVWYITTIEHLIELIKYCSSKYTRSKLRKALPKQYVYIIEELLYKSNEYQNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPIIKRRPNFEMEERLVLEKVNYDTNEITVYGNTYPLKDTCFQTINRNNPAELLPEEEEVMNKLLLSFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGHTYSGQELLDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHKEEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRVVDKELQRKKIRDTNIGKELQAQIDILKMLMHDRYLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: MURD_PORG3
Sequence: MDRLKYDIVVLGAGESGVGAALLAQAKGLHVFVSDYGKIAPKYKEELNRYAIPYEEGRHTEAIILEAKEIIKSPGIPDTAPVIRQAVAKEIGIVSEIEFAGRYTDAFMVCITGSNGKTTTTMWLYHTLCKAGLDVGLAGNVGFSLARQVAYDPHPYYVIELSSFQLDNMYDFRANVAILLNITPDHLDRYDHRFELYAEAKMRITRNQQPEDCFIYWEDDPFISRWVAEHPPVARLLPFAMEARTDNTTAWINEKNELVVMNLNSPFVMDEELLALSGMHNRHNAMATAIAAKAMDIKNEAIREALQDFKNVPHRLEKIARVKGVDYINDSKATNVNSTWYALESMKTRVILILGGTDKGNDYTDIENLVLSKVDGLIFLGIDNEKLHKFFDGKISRIADACSMHEAVSLAYKMASKGDTVLLSPACASFDLFQNYEDRGDQFRKEVLNL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ALCBS
Sequence: MPAIASSPQSRSTDMAVRHDWKRSEIDALFALPFNDLLFQAAALHRAHFDPNAVQVSTLLSIKTGACPEDCKYCSQSGHYNTELEKEKLLEVSRVVEEARAARQNGASRFCMGAAWRSPRDKDMPYVLDMIRQVKDLGMETCMTLGMLNEGQAGALAEAGLDYYNHNLDTSPEYYGQVITTRTYNDRLSTLANVRDAGMKVCCGGIVGMGEERNDRVGLLQQLANLPHHPESVPINMLVKIEGTPLADVDDLDPFEFVRTVAVARILMPQSYVRLSAGRQEMNDEAQALCFMAGANSIFYGERLLTTDNPEANHDQRLFKRLGIHPLDPRHEASDEAHEEAIQAQVSEQQAEEAGLFYNAMDSKRTAKHVLDKDTGRPTATEH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NDHH1_GLOVI
Sequence: MSMLETRAERMVINLGPHHPSMHGVLRLIVTLDGENVVDCVPVLGYLHRSMEKIAESRTIIQYLPYVTRWDYLATMFTEAITVNAPEQLAGVQVPRRARYIRVIMLELSRIASHLLWLGPFMADIGATSPFFYIFREREMIYDLFEAATGMRMMHNYFRVGGVAVDLPYGWVDKARDFCNYLPPKIDEYERLITNNPIFRGRVEGLGYIGREDAINWGLSGPMLRASGVNWDLRKVDHYEIYDELDWNVAWDTGGDTLARYVVRIQEMRESVKMIRQALDQLPGGPYENLEAQRLSGGPKSEWNGFDYQFIGKKSSPTFKMPRGEHYVRVEAPKGELGVYLIGDDSTFPWRWKIRPPGFINLAVLPKLVQGTKLADLMAILGSVDIIMGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H 1, NAD(P)H dehydrogenase subunit H 1, NADH-plastoquinone oxidoreductase subunit H 1, NDH-1 subunit H 1, NDH-H 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GET2_VANPO
Sequence: MSSELSETEKRKLIRERRQKKFSNGGASARLNRITGQAENSQLDTESPLDSKSSRETTPTVTKVDSNTEEMDELLENIATSPSNKVEKSQKKKEQATSPQETIDPELEIFKQLAENQQNDVSTPDLFSMLRSMKDNMAKSAATDTNPPLEPVDQQLLDYNNYLINNLKVWSIIFKWCFFLIPYLFALTRSEPISFLPEQFSNPSNFFMIFLSFEIVATSIYFQKLQNIEKSNKINGFQSNNKIVNLVSLIPEGVLPVPDIKGKVIMALQYWDVFSMFLTDICFVLVMMGLFKLI
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: G6PI_SODGM
Sequence: MKDINPSHTAAWKALQQHFATMKDVQISDLFAQEPERFSSFSATFNDQMLVDYSKNRITAETLTRLLALAEECGVKEAIAAMFSGEKINRTEDRAVLHVALRNRSNTPINVDDKDVMPDVNAVLVKMKQFCDRVIGGEWKGYTGRIITDIVNIGIGGSDLGPYMVTEALRPYKNHLNMHYVSNVDGTHIAETIKDLDPATTLFLVASKTFTTQETMTNAHSARDWFLKTAGDEQHVARHFAALSTNAKAVAEFGIDTENMFEFWDWVGGRYSLWSAIGLSIALSLGFDNFEKLLSGAHAMDHHFVSTPLDKNLPVLLALIGIWYNNFFGMETEAILPYDQYMHRFAAYFQQGNMESNGKYVDREGHPVSYQTGPIIWGEPGTNGQHSFYQLIHQGTKIVPCDFIAPAISHNPLTDHHAKLLSNFFAQTEALAFGKSREAVEQEFSAAGKSPDQVQHVAPFKVFEGNRPTNSILLREITPYSLGALIALYEHKIFTQGAILNIYTFDQWGVELGKQLANRILPELAQDNPIDAHDSSTNGLINRYKSWRH
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_MARMS
Sequence: MIIGVGTDLVEIARIAQSIERLGERFIDRILTAAEKERWSEISNLEKANSFVAKRFAAKEAAVKALGTGIGLGVSFQHFNVSNLPSGQPVLTVDESIIARYDFPVSWHLSLTDEKAYAQAFVILESK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R9BP_BOVIN
Sequence: MAKEECKALLDALNKATACYHHLVLTIGGSADSQNLREELQKTRQKAQELAVAIRLRLTAPLRDRSLGAEERAEFERLWVAFSGCLDLLEADMRRALALSTEFPLQEPRRPLVRTGVEGGATGVAARALSVRSLRHEAHRDFDVEDLHQLEREILQVGEMIQDMEMKVNVPRWTVQARQAAGAELLSSASAGVSSVGGVSVEQRTGPCDLSKAKAATIFSAVLLAAVALAVCVAKLS
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction.  Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform.  Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place.  Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale.  It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 9-binding protein, RGS9-anchoring protein.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: H2B3_TIGCA
Sequence: MPPKVSGKAAKKAGKAQKNISKGDKKKNRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MCH_METOR
Sequence: MSASQSYPSINALSGPLVERLVADAPTLRLSVSQAAGGARMVDAGAQARGSIEAGRRIAEICLGGLGTVTIAPSGPIASWPYSVTVHSADPVLACLGSQYAGWSLADETGDSGFFALGSGPGRAVAAVEDLYQELGFRDSATKTALVLEAAGGPPESVVAKVAEASGLKPEDLTFIYAPTQSLAGSTQVVARVLEVALHKAHTVGFDLHAIVDGIGSAPLSPPHPDFIKAMGRTNDAIIYGGRVQLFVDADDADAKQLAEQLPSTTSSDHGAPFAEIFARVNGDFYKIDGALFSPAEAIVTSVRSGATYRGGRLEPTLVDASFA
What is the function of this protein?
Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_ACTP7
Sequence: MKYELKTTSGNARRGRLTFSRPKGEYVVETPAFMPVGTYGTVKGMTPEEVAATGAQILLGNTFHLWLRPGQEVMKSHGDLHGFMQWHGPILTDSGGFQVFSLGKLRKIKEEGVTFQNPISGEKIFLSPEKSMEIQYDLGSDIVMIFDECTPYPATFDYAKNSMEMSLRWAKRSRDRFDELQNPRALFGIVQGGTYEELRKISVEGLVNIGFDGYAVGGLAVGEPKEEMHRILEFTTPLLPQDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVSNGIVKIRNAKYKTDTTPLDPECDCYTCKNYTKAYLYHLDKCGEILGARLNTIHNLRYYQRLMAQIRQAIEEDRFDDFVVEFYAKIGKEVPPLQSEVNK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: VF602_ASFK5
Sequence: MAEFNIDELLKNVLEDPSTEISEETLKQLYQKTNPYKQFKNDSRVAFCSFTNLREQYIRRLIMTSFIGYVFKALQEWMPSYSKPTHTTKTLLSELITLVDTLKQETNDVPSESVVNTLLSIADNCKTQTQKSTEAKTTIDSFLREHFVFDPNLHAQSAYTCASTCASTCASTCASTCADTNVDTCTDTCASTCADTNVDTCASTCADTCASTEYTDLMDPERIPLHIMQKTLNVPNELQADIDAITQTRQGYRAAAHILQNIELHQSIKHMLENPKAFKPILFNTKITRYLSQHIPPQDTFYKWNYYIEDNYEELRAATESIYPEKPDLEFAFIIYDVVDSSSNQQKIDEFYYKYKDQIFSEVSSIQLGNWTLLGSFKANRERYNYFNQNNEIIKRILDRHEEDLKIGKEILRNTIYHKKAKNIQETGPDAPGLSIYNSTFHTDSGIKGLLSFKELKNLEKASGNIKKAREYDFIDDCEEKIKQLLSKENLTPDEKSQLEKTKKQLENALEMLNVPDDTIRVDMWVNNNNKLEKEILYTKAEL
What is the function of this protein?
Plays an essential role in the assembly of the icosahedral capsid of the virus (By similarity).  Allows the assembly of 3 molecules of hexon protein p72 and formation of a thermostable trimer (By similarity).
What are the official names of this protein?
Protein B602L, pB602L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B602L family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: FMDA_METME
Sequence: MKTIVKLDLDKKPWEQDGQIHNRWHPDLPMIAMVKPGDEFRVECMDWTGGQIGNNDSANDVRDVDLTQVHYLSGPIGVEGAEPGDLMVVDILDVGTFDDSQWGFNGLFAKENGGGFLTDHFPEASKTIWDFHGVYTTSRHVPKVRYAGIMHPGLIGCLPSKELLDTWNKREGDLIATDPDRVPPLACPPTSQSAVMGRLSGDAAKKAAAEGARTVPPRDHGGNCDIKNLTKGSRVYFPVYVKDGGLSMGDLHFSQGDGEITFCGAIEMAGYLDIKVGLIKDGVKKYGIKNPVFQPSPITPTYRDYMIFEGISVDEAGKQHYLDVHIAYRQACLNAIEYLKKFGYSGEQAVSILGTAPVEGHISGIVDIPNACATLWIPTEIFEFDIRPNADGPKIMVPPGVDVSFTS
What is the function of this protein?
Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth.  Also acts, more slowly, on acetamide, propanamide and butanamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acetamidase/formamidase family.
Protein: TNAA_ECO45
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: SYL_PROM2
Sequence: MISPDKQYESFTNLYNPSEIEKKWQLIWTENNLYKTDELTENSDKFYALSMFPYPSGNLHMGHVRNYVITDLIARFHRFKGKSVLHPMGWDAFGLPAENAAIERGISPSVWTKQNISHMRSQLKLLGLSVDWDREFATCDENYYIWTQYLFLELYKAGLVYQKESEVNWDPVDNTVLANEQVDSEGKSWRSGAVVEKKLLKQWFLRITNYADELLKDLEKLDNWPERVKIMQDNWIGKSIGTNINFNLNTNPEEKITVFTTRPDTLFGVTYLAISVNHSLIKYISDQETIQDIENLKQYLKNNKNNELEKIGIKTSLIAINPINSEPIPIWVASYVLDEYGTGAVMGVPAHDQRDFEFAKKNNIDIKQVIINDKSEKTNELDKAYVENGYLMNSDQYNFMENTIAKLKISEEGVDNGWAENKIQYRLRDWLISRQRYWGCPIPIVNCKKCGSVPLKQSELPVALPKDIDISANKINALGDNNHWINTTCPKCGIAAKKETDTMDTFMCSSWYFLRYPSSKCSNKPFEKIEINKWLPVDQYVGGVEHAILHLLYARFFTKALRDNELFEIDEPFKKLLTQGMVQAAAYKNNKTGKYVSPSDINDLSNPTDPIDNTKLEVLFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDLEWGDTDVEGQFRFLNRIWKLYINCAKDINSKSNSYPDREKSLIKSMNIAIKEISNDILNNQFNTAISELMKFYNSLANSINDVNNTLKIEALKTFCILLAPFAPHIAEEIWHLIGFKKSVHLEYWPSFNAEALKEDSYELVIQVNGKVRDKVKINNDMSEDQIKELTLKRPNILKWTQDKEIRKIIIVKGKIINIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_YERPG
Sequence: MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETASI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: SNE_ARATH
Sequence: MSSEKRVGMVEKSNNKRQRVNQVPVFSINDHHDVLVEILRRLDGSSLCSAACVCRLWSAVARNDSIWEELCFRQVSPRPSLSLRSVVSALGGYRCLYFLCIRPVLARLPKLLWTRDQLQLSLSLYCVHYYERLYVGAWLGDAPPSSLIFLRKPVNVV
What is the function of this protein?
Essential component of a SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway.  Upon gibberellin treatment, such complex probably mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to activate the pathway.  Can partially complement the absence of GID2/SLY1.
What are the official names of this protein?
F-box protein SNE, Protein SNEEZY, Sleepy protein 2.
What are the subcellular locations of this protein?
Nucleus.