PharMolix/UniProtQA huggingface dataset:
Protein: SYL_PSEU2
Sequence: MHELYQPREIEAAAQTFWDEQKSFEVSEQPGKDTFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMLGKNVLQPLGWDAFGMPAENAAIDNNVAPAKWTYENIDYMKTQLKSLGLAVDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYADELLESLDELPGWPEQVKTMQRNWIGRSRGMEVQFPYDQASIGEAGALKVFTTRPDTLMGATYVAVAAEHPLATLAAQGNPALQAFIDECKGGSVAEADVATQEKKGQATSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATQYGLPIKPVVRTSAGDQTPAPWQPAYGEHGELINSGEFTGLTFQDAFDAIEAALVKKSLGQSRTQFRLRDWGISRQRYWGCPIPIVHCDTCGDVPVPEDQLPVVLPEDVVPDGAGSPLARMPEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVEPNAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVNAETYFRMETSGKKTWINPADVTLERDAKAKVISARLTSDGLPVEIGGTEKMSKSKKNGIDPQTMIDQYGADTCRLFMMFASPPDMSLEWSDSGVEGSHRFLRRVWRLAQAHVTQGPSTGLDVAALSDEQKAIRRAIHQAIRQASQDIGQNQKFNTAVAQVMTLMNVLEKAPQDTPQDRALMQEGVETVALLLAPITPHISHELWKQLGHNEPVIDAGWPAFDASALVQDSLQLVIQVNGKLRGHIEMPASASREEVEAAARVNENVLRFTDGLTIRKVIVVPGKLVNIVAS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRRA_STAAC
Sequence: MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPAK
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation (PubMed:24222487).  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate (PubMed:16859493, PubMed:24222487).  Functions as a transcription regulator by direct binding to promoter regions of target genes (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein SrrA, Staphylococcal respiratory response protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGO_YERPE
Sequence: MLAVYLHGFILSAAMILPLGPQNVFVMNQGIKRQHHLMSASLCALSDIILICAGIFGGSALLSRSPLLLALVTWGGVAFLMWYGWGALMAAWRGDGVASSATSVTQGRWRILVTLLAVTWLNPHVYLDTFVVLGSLGGQLLPDIRPWFALGAVTASIVWFFALALLAAWLSPWLNRPVAQRIINLFVGGVMGFIAFQLARQGFGL
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TMX2B_DANRE
Sequence: MALLTPLFAFLYHLPQVYKWLLKPYYIASLFMSIAFVMIRKMPGVCEHLSTQREDGNSCDFDWREVEILMFLSAIVMMKNRRAITIEQHVGNIILFCKVANVILFFRLDIRLGLLYLTLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELEKDHRVTWIVEFFANWSPECQSFASVYADLSLKYNCAGLKFGKVDIGRYGEVSKKYRVSTSPLSKQLPSLVLFQGGKEVMRRPQVDKKGRAVSWTFTEENIIREFNLNELYQKSKKLGKTKEKLERPSELVFSTVPEEEEPEAETISAMDTESKKDK
What is the function of this protein?
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 2-B, Thioredoxin domain-containing protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria.
Protein: Y1617_VIBPA
Sequence: MPSFDIVSEIDTVELRNAVDNANRELSTRFDFRNVNASFELVEENVKVSAEGDFQLKQMRDILRGHLAKRNVDANAMDAQNPEVTGKNWHQNILFRQGIDTPTAKKLVKLIKDAKLKVQASIQGDKVRVTGKKRDDLQATIAAIREAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein VP1617.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: PG122_MONPV
Sequence: MSFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMYRKKRLFLNYSNYLNKQERSILSSFFSLDPATADNDRINAIYPGGIPKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
mRNA-decapping protein OPG122.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: TATC_PEA
Sequence: MGLGTTTVPTNILPQFGLHRTHLNPIRVNNSTGFSYPLSLRKNKSFDRLVCFAVDDEIREKQQQQLSTSSTRLGSAVEERPENKDMIDGISEEALENFKEDGERSAIYDFLYPSKELLPDDKEMSIFDHLEELRERIFISVLGVGGSILGCFAFSKDLVKILEAPVKSEGVRFLQLAPGEFFFTTLKVSGYCGLLLGSPIILYEIIAFIIPGLTKEERKFLGPIVLGSSVLFYAGITFSYLVLVPAALNFFVNYAEGAVESLWSIDQYFEFVLVLMFSTGLSFQVPIIQLLLGQLGLVSGDKMLSVWRYVVVGAVVAAAVVTPSTDPLTQVLLAAPLLGLYLGGAWMVKLAGR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TATC, chloroplastic, Protein TWIN-ARGININE TRANSLOCATION C, cpTatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=The N-terminus is located in the stroma.
Protein: RL28_SHESA
Sequence: MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEEEKRFVQLRVSTKGIRLIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: YCFC_SCHPO
Sequence: MNRRVTLGALAAAVGVGYYMTRHNRQASSRLEQKNAEIVRAVENEGQRFDKAVGETTEKAKSYLQSGKERVVDELDKPRENVKNVLSEAQAKGTEQAEALKKGTSKWF
What are the official names of this protein?
Uncharacterized protein C1393.12.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB19_BOVIN
Sequence: MQFSSSARTVDENFDYLFKIILIGDSNVGKTCVVQHFKSGVYMEAQQNTIGVDFTVRALEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKCDLWEKRHVLFEDACILAEKYGLLAVLETSAKESKNIDEVFVLMARELMARHSLPLYGEGAPGSLPLESTPVLMAPAPREKNQCTC
What are the official names of this protein?
Ras-related protein Rab-19.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: BLCAP_PONAB
Sequence: MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT
What is the function of this protein?
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.
What are the official names of this protein?
Bladder cancer-associated protein.
What is the protein family that this protein belongs to?
Belongs to the BLCAP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BUD16_YEAST
Sequence: MPRLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETDLKELLSGLFDNFSQDYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDEGQLYVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQTIPVIIVTSCDCKMFDDKDFIYCVASMEGKTPIVYRVPFIDSYFTGVGDLFSALLLDRVYKILSNPTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYETINIHQTDYIYARL
What is the function of this protein?
Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (By similarity).  Important for bud site selection.
What are the official names of this protein?
Putative pyridoxal kinase BUD16, Bud site selection protein 16.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KGUA_PARXL
Sequence: MTDHHTRETPRNPYAGAYPGNLFMVVAPSGAGKSTLVNALLAGDDAIRLSISYTTRPPRPKELDGEHYHFTTVDDFMKRHDAGEFLESAEVHGNYYGTSRVWIEDQMKSGHDVLLEIDWQGAQQVKKQFHNAVEIFILPPSLEALEERLKKRGQDEPNVITRRLLAAGSEMAHAAEAEYVVINENFDRALSELQCLVAATRSRFASQYARHTQLFVQLGIHLPHA
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR_MYCLE
Sequence: MTVVGLIWAQSTTGVIGRDGGMPWRVPEDLTRFKQLTMGHPVVMGRRTWDSLPVGVRPLPGRRNIVLSRQIDFMAEGAEVFGSLEETISNLETEPEMWVIGGEQIYRLALPLATRCGVTEVDTYLLHEDDDVLAPVLDDTWVGVTGEWLVSCSGLRYRLHSYHRS
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: THIQ_RHILO
Sequence: MRGKGVPVRLDKVSFSYGEAPLTFDVAFAAAEITAIMGPSGSGKSTLLNLVAGFETPQSGGVLIGGVDVGAAPPAARPVSMVFQENNLFAHLSVEQNVGLGRSPSLRLTEVDREAIDGALARTGLGGKEKRLPRELSGGERQRVALARVLVRDRPVLLLDEPFASLGPALRDDMLDLVAGVHAERGMTVLFVTHQPQDARRIGRNVVFLDNGTVAATGSADDFFAGAGPEAFRRYIGASAGNAVSQDIARKRT
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ERO1_YEAST
Sequence: MRLRTAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDRNDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLPEYWQPEILGSFNNDTMKEADDSDDECKFLDQLCQTSKKPVDIEDTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIGETGESLAKDAFYRLVSGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGNFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFCDLVNKEIKNKMDNVISQLDTKIFNEDLVFANDLSLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEINDADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSIRYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNVLEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ
What is the function of this protein?
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.  Acts by oxidizing directly PDI1 isomerase through a direct disulfide exchange.  Does not act as a direct oxidant of folding substrate, but relies on PDI1 to transfer oxidizing equivalent.  Also able to oxidize directly the PDI related protein MPD2.  Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI1 and related proteins.  Reoxidation of ERO1 probably involves electron transfer to molecular oxygen via FAD.  Acts independently of glutathione.  May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress.
What are the official names of this protein?
Endoplasmic oxidoreductin-1, Endoplasmic reticulum oxidoreductase protein 1.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: AL1A2_TAEGU
Sequence: MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKYTKIFINNEWQNSESGRIFPVYNPATGEQICDIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGHLLDKLADLVERDRAILATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRKSVKRAKRKIVGSPFDPTTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGSKSGNGREMGECGLREYSEVKTVTIKIPQENS
What is the function of this protein?
Converts retinaldehyde to retinoic acid (PubMed:10985355).  Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal (By similarity).  Has only very low activity with benzaldehyde and acetaldehyde.  Displays complete lack of activity with citral (PubMed:10985355).  It is responsible for the ability of brain sites to synthesize retinoic acid.  Its activity in the high vocal center (HVC) is required for the song of juvenile zebra finches to become stereotyped (PubMed:10985355).
What are the official names of this protein?
Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II), zRalDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_LEPBA
Sequence: MRNFRRFTIALLVLFLGPIGAADTKETPGMDRQNTSNQFWWPERLDLAPLRQHGSESNPLGRQFHYAKEFKELDIQTLKEEIKTVMKTSQDWWPADYGHYGPFFIRMAWHSAGTYRISDGRGGAGGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGKKISWADLMVLTGNVALESMGFKTYGFAGGRTDDWEADLVYWGPEKKFLEDQRYKGNRELKNPLAAVQMGLIYVNPEGPNGNPDPLAAAKDIRETFGRMAMNDEETVALIAGGHTFGKAHGKSDPSKHVGKEPAAAGLEEQGFGWKNNYKKGNAEDTITSGLEGAWTANPTKWTTQYLNNLFGFEWVQTKSPAGAIQWVPKDGAGANMVPDAHDKSLRHAPIMFTTDLALKFDPSYKVIAKRFQENPKEFELAFAKAWFKLTHRDMGPLTRYIGKDLPKEPLIWQDPVPAVNHKLVGPKEIESLKGKILKSGLSVPQLVRTAWASAASFRSTDMRGGANGARIRLSPQKNWPVNDPDELSKVLKKLEQIQEEFNKSGNKISLADLIVLAGNAAIEEAAKKAGVKVTVPFTPGRTDATIEQTDEYSFSVLEPKADAFRNYYGPGNLMSPTEMLVDRANMLSLSIPEMTVLLGGMRSLDANAGKSKHGILTTKPGVLSNDFFVNLLDMSTKWQKSEQTEGLYEGLDRKTGSKRWTATSVDLIFGSHSELRAVAEVYASDDAKEKFVKDFVSAWNKVMMLDRFDVK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL11_RICB8
Sequence: MAQKIEGHINLNVNAGEATAAPPIGSTLGQRKVNIMEFCKAFNAATQSIEKGTPLPTVITIYVDKSFTFIVKTPPASYLIKKYAKVKKGSGATKKEAVVGKITMDDCREIAKLKMPDLNTKDIKAATKIICGSAASMGIEVVGN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TRPA_RHIWR
Sequence: MTRLAETFARTRAEGRAALVTFVTGGDPTPGDMGPILDALVAGGADVIELGMPFTDPMADGPAIQRANLRALGAGTTTADLLAIAAAFRQRHPSVPLVLMGYANPMVRRGPEWFAAEAAKAGVDGVICVDIPPEQDGALGPALRAAGVAPIRLATPTTDAARLPAVLEGASGFLYYVSVAGITGMQQAGQASIEAAVARFKAATDLPVAVGFGVRGPEQAEAIGRVADGVVVGSAIVDLIGEHGAAAAGPVRDFTATLSAALRRAAQEKAA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RS18_LACLA
Sequence: MAQQRRGGFKRRKKVDFIAANKIEVVDYKDTELLKRFISERGKILPRRVTGTSAKNQRKVVNAIKRARVMALLPFVAEDQN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TRXB_BACSU
Sequence: MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYAYGDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIGVPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEGVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIGMLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQSVQHYVEELQETLKTLK
What are the official names of this protein?
Thioredoxin reductase, TRXR, General stress protein 35, GSP35.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBB_BRUA4
Sequence: MKGFMIAAPASGSGKTTVTLGLLRALKRRGEALAPVKAGPDYIDPAYHKAASGVDCFNLDPWAMRPELISALSSRMTESGARLLVAEGMMGLFDGAMDGKGSSADLARLLDLPVVLVVDCARQSHSIAALVWGFSQFRKDVLIAGIILNRVGSSRHEAMLRGALEPLRIPVLGALPRDTALSLPERHLGLVQAGEHSDLESFLEHAADTMETHIDLDALQTIWSRPKRFDAMANVPRLKPLGNHIAVARDDAFAFAYAHLFEGWRRRGVEISFFSPLGDESPRQDADAIYLPGGYPELHAGRLAQAGRFQAGIREAAARGVTVYGECGGYMVLGESLQDAEGVAHPMLGLLQLETSFAKRKLHLGYRVLEPLEGSPWTEPLKAHEFHYASIVREGKADRLFRVRDAVGDDVGEAGLRVGSVSGSFMHVIDFCGEKA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Hydrogenobyrinate a,c-diamide synthase, Hydrogenobyrinic acid a,c-diamide synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: GLYC_MOBVC
Sequence: MGQIVTFFQEVPHIIEEVMNIVLITLSLLAILKGIYNVMTCGLIGLLTFLFLCGKSCSTIYKDNYRLMQLNLDMSGLNATMPLSCSKNNSHHYIQVFNTTGLELTLTNDSLIGHKWCNLSDAHKKDTYDHTLMSIISTFHLSIPNFNHYEAMACDFNGGKISIQYNLSHSSETDAMNHCGTVANGVLEVFRRMTWCTHCDTPLGASIAGFNCVRTSYKYLIIQNTTWEDHCTMSRPSPMGYLSLLSQRAREIYISRRLMGTFTWTLSDSEGNDLPGGYCLQRWMLIEAEMKCFGNTAVAKCNQQHDEEFCDMLRLFDFNKEAIHRLRVEAEKSISLINKAVNSLINDQLIMRNHLRDIMGIPYCNYSRFWYLNDTRSGRTSLPKCWMVSNGSYLNETHFSSDIEQEANNMITEMLRKEYERRQGTTPLGLVDLFVFSTSFYLISVFLHLIKIPTHRHLVGKPCPKPHRLNHMGVCSCGLYKQPGLPTKWKR
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: RR7_CRYJA
Sequence: MSRQSTVEKKIEKFDPIYHNRLVNMVVNRILKHGKKSLAYRIFYQSLKKIQQKTEKNPLIVLRQAIQKLTPKLIVKSRRVSGSTYQVPIEIKKKEGKILAIRWLLESSRKRSGRNMHFKLSYEIMDAAREKGNAIRKKEEIHKMAESNKAFAHYH
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CM3J_CONRE
Sequence: GCCSPWNCIQLRACGCC
What are the official names of this protein?
Conotoxin reg3j.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BYST_RAT
Sequence: MPKLKVTRGARNQERHAPLAEQILAGDAVRAGTREKRRRHGVEEEEEYVGPRLSRRILQQARQQQEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDEEWPTLEKAAKMTVVNHQAEVVVDPEDERAIEMFMNKNPPVRRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLCKYRSGILPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLHSSAAMLKIAEMEYSGASSIFLRLLLDKKYALPYRVLDALVFHFLAFRTEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVVVTME
What is the function of this protein?
Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.
What are the official names of this protein?
Bystin.
What is the protein family that this protein belongs to?
Belongs to the bystin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Associated with 40S ribosomal subunits.
Protein: MTRC_NEIGO
Sequence: MAFYASKAMRAAALAAAVALALSSCGKGGDAAQGGQPAGREAPAPVVGVVTVHPQTVALTVELPGRLESLRTADVRAQVGGIIQKRLFQEGSYVRAGQPLYQIDSSTYEAGLESARAQLATAQATLAKADADLARYKPLVSADAISKQEYDAAVTAKRSAEASVKAAQAAIKSAGINLNRSRITAPISGFIGQSKVSEGTLLNAGDTTVLATIRQTNPMYVNVTQSASEVMKLRRQIAEGKLLAADGAIAVGIKFDDGTVYPEKGRLLFADPTVDESTGQITLRAAVSNDQNILMPGLYVRVLMDQVAADNAFIVPQQAVTRGAKDTVMIVNAQGGMEPREVTVAQQQGTNWIVTSGLKDGDKVVVEGISIAGMTGAKKVTPKEWAPSENQAAAPQAGVQTASEAKPASEAK
What is the function of this protein?
Cell membrane lipoprotein, involved in cell membrane permeability to hydrophobic compounds such as antibiotics, dyes and detergents.
What are the official names of this protein?
Membrane fusion protein MtrC.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: PH2_PRUSE
Sequence: AGTYPPVVXATLXRTH
What are the official names of this protein?
Prunasin beta-glucosidase 2A, Prunasin hydrolase isozyme IIA, PH IIA.
Protein: A21_LOXVA
Sequence: WIMGHMVNGIDQIDEFLRLGSNSPEFDINFDKDAKPVYTYHGVPCDCFRSCLRWEYIGDYLTALREVTTPGNPKFRENLSLFVFDLKTNSLYDSQAGKAGENLADDIFKYYWNEGNNGGRAYMIISIPDIEHYDLMTSFKHYFISNGHEELLDFVGFDFSANDNIPDVEKVFEKVRVPGVPDRVWQSDGITNCIMRGLNRVKEAVKVRDAGGIINKVYVWTVDKVPSIKAALDAGVDGVMTNHPDVVVGVLREDGYKDKFRYASYNDNPWETFKAE
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LvSicTox-alphaII1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.