PharMolix/UniProtQA huggingface dataset:
Protein: ODO1_BACC3
Sequence: MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFEIFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAANGQSLLERAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKEVYTQSLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNQKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEIETITQFTQEQLKSDYAQVPPADTSDATIHVKVPDVVAKGIQSIDTGVELDSLRAINEGLLSWPEGFNVYPKVKKILERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTNETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQALFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGTKPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEIHIVRIEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQELIVSHALDVKYNFRQDKLEIEVFSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: PANC_COXB2
Sequence: MTKVIEALSDWQSIRKTINDLSVGFVPTMGNLHAGHLSLLERSKCENTITVLSLFINPTQFNDKNDFKNYPRTLAQDIAMAEENGIDYVLAPTDDALYPDQYAYKITNSTINNQEAEFRPRHFDGVLTVVMKLLLLVKPTRAYFGEKDYQQLQLVKGLAEAFFLDTEIIGCKIVRNEFGLPLSSRNRRLTEDQYQLAQRFSEIFHSDLSCDEIKNALIQEGIIVDYIEDYNERRFAAVHVGDIRLIDNIPFAKDKKC
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_NOSS1
Sequence: MKQIFIWLIKGYRMFISPLYPPTCRFRPTCSMYAIEAIERFGVFRGGWMAIRRILRCHPFHPGGYDPVPELGEHCCHHDSGNKG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIPK3_HUMAN
Sequence: MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGSAFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISCSNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression.  Phosphorylates JUN and RUNX2.  Seems to negatively regulate apoptosis by promoting FADD phosphorylation.  Enhances androgen receptor-mediated transcription.  May act as a transcriptional corepressor for NK homeodomain transcription factors.  The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.  In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
What are the official names of this protein?
Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK, Fas-interacting serine/threonine-protein kinase, FIST, Homolog of protein kinase YAK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GGAG_MLVFF
Sequence: LGDVPGTSGAIFVARPESNHPDRFGLFGAPPLEEGYVVLVGDRGLKRFPPPSEFLLSVWNRSRAARLVCCSIVLCCLCLTVFLYLSENMGQAVTTPLSLTLDHWKDVERTAHNLSVEVRKRRWVTFCSAEWPTFNVGWPRDGTFNPDIITQVKIKVFSPGPHGHPDQVPYIVTWEAIAVDPPPWVRPFVHPKPPLSLPPSAPSLPPEPPLSTPPQSSLYPALTSPLNTKPRPQVLPDSGGPLIDLLTEDPPPYRDPGPPSPDGNGDSGEVAPTEGAPDPSPMVSRLRGRKEPPVADSTTSQAFPLRLGGNGQYQYWPFSSSDLYNWKNNNPSFSEDPAKLTALIESVLLTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGEDGRPTQLPNDINDAFPLERPDWDYNTQRGRNHLVHYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVAMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRRETEEKEERRRAEDVQREKERDRRRHREMSKLLATVVSGQRQDRQGGERRRPQLDHDQCAYCKEKGHWARDCPKKPRGPRGPRPQASLLTLDD
What is the function of this protein?
Plays a role in viral particle release.  Presumably acts by facilitating the fission of the virion bud at the cell surface.  May prevent the antiviral activity of murine APOBEC3.
What are the official names of this protein?
Glyco-Gag protein, Gross cell surface antigen, glycosylated Pr80 gag, gPr80 Gag, gag-gPr80.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: FER6_ZYMTI
Sequence: MSKSLAYPPRKWYRRVPFLSDKSSLTLLDSNGNRKITPEASASLWNWFFFSWLNPLIAIGYSRPHIQSELYLLPPSSDVSVYAGKLDGHIEGLRERVPEGGGKRRRFNFHSPSWRLARALNASVLVWFWVGGAMKLFADVATITSPLLVRAIIRFLQTSEQNRKAGLPEPSIGQGFGMAIGLALLLASGVMANVHGFYRSYTSGILLRSALIDSLFRRTSAFSPLERAKHNLETSRIISMISTDVSRIDFACGYFHATWTSVIQILICLGLTIASLGPAALTGFGLMAILVPSQNYIVKYLFLLRKRSMPFTDARLSAISEALASIRLVKVYAWESALLSKISFLRRSELKLLRSRLLLRAVNVALSFSVPTLAAVVSFVTYAALGNELDAAEVFSALTLFMLLRTPLLLLPVAFGAAADGANAIQRLAGAFDAPMPDHGLPIDGDIEAAVEVKDATVSYRVQDHSDEKSEKQTSSFQLTNLTVHINRGELFMIVGPVGAGKSTFLGSLVGETRLETGHAVLGSRAAYAPQQAWLKSGSIRENIVFGRPWNPDRYNSVLSACCLTQDLSTFPSGDETMIGENGISLSGGQRQRVALARTIYEPSPLLLLDDVFSALDAHVQSEVVQKVVLERDPGTTLVLVTHSLHLLRHADRICCLNEGRVEEMGSFAELMGKEGGQMRRVVEEFASKSSAEEEEVEDGDLKDGVPSTDGGDASQTTSNKAMMQTEERFIGSVTARTYASYIRAGKPAFTLTFFILSMLIFQGGSILSPLWLQWWQEGRFPTLSSGTYMGVYAALGVSQAIGLLAMSSIFGFFIFYSACQIHADAIRSVLYAPISFFDTTPLGRITHRFSKDIDAIDNVIGEAFRMLLSTVAQVVGAVVLISIILPWFLLAVFVIVILYILTGMYYRPTARELRRLDALTRSPIYEHVSESLNGIMVIRSLGALQTTLDRNRENLNTENSPYWLSVACQRWLSVRLDLLGTCLVLLVGLIVVGSRSSISAAQGGVALSYIVTVQAVFGFMIRQSAEIENNMNAIERLLYYSHDVPQEPPHKREGDVGLVEKKWPGQGAIEMRDVVFTHREGLEPSLRGVNLVIPAGCRLALVGRTGSGKSTMLAALVGMGEITAGTIMVDGVDVSTIGLNLLRKRIAFMPQEAAVLSGTLRYNLDPFGEHDDADLWRVMHQVGLSSISAQSSAETLTSSDQEKSSPDDAAISPSSHSHSQHLTLDTPIHAERSDLSSGQRSLISLARALIKDASIFVLDEATASMDMELDHRLQRVLRENLRGKTTIVIAHRLDSVVGSSDLICVMDEGRVAQCGSPMDLFGEEGGHFRSLCSDAGLGELDLVEARRRFVSS
What is the function of this protein?
Multidrug resistance protein; part of the gene cluster 14 that mediates the biosynthesis of a ferrichrome A-like siderophors which may contribute to organismal virulence.
What are the official names of this protein?
ABC-type transporter MYCGRDRAFT_41235, ATP-binding cassette sub-family C member MYCGRDRAFT_41235, Ferrichrome A-like siderophore biosynthesis protein MYCGRDRAFT_41235.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_BACAN
Sequence: MARKTNTRKKRVKKNIEAGVAHIRSTFNNTIVTLTDTHGNALSWSSAGALGFRGSRKSTPFAAQMAAETAAKAAMEHGLKTLEVTVKGPGAGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: XPT_STAEQ
Sequence: MESLGRKVKEDGVVIDEKILKVDGFLNHQIDAKLMNDVGKTFYESFKDAGITKILTIEASGIAPAIMASFHFDVPCLFAKKAKPSTLKDGFYSTDIHSFTKNKTSTVIVSEEFLGADDKVLIIDDFLANGDASLGLNDIVKQANATTVGVGIVVEKSFQNGRQRLEDAGLYVSSLCKVASLKGNKVTLLGEA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ECOSE
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MURD_TROWT
Sequence: MSRVEGLTSWYSDWQGLSAAILGIGVSGFAAADSLRELGVDVTVYAPEKHTRYNKLLDAIGARYVCAYLDELCEVDVDFIVVSPGISPDNPVIKRLRDRQIPILSEIELAWRVRDKVNTCPWILITGTNGKTTTALLTGSMLAKDGARVAVCGNIGTPVLDAVRNPKGFDYLVVELSSFQLSLLPMHGNGAVKGFSSACVNLDEDHLEWHGAKELYYCAKSRVYHGTTGFCVYNLDDEETKKMVEQACVARNVRAIGFGLCVPDVGQVGIVDGILCDRAFLSARKDSALEITSVEKLEKNKLSMRHIISDVLCAVALARSVETNPLSISRALDEFCLSPHRTEVVAKEMGVMWVNDSKATNPHAVIASLSNFSRVILIFGGLMKGVDVSGIFDRFYETIKAVVVIGKNQSFVGNIKCKKIVCIPDSNDPMSEAVAAADLLATPGDTVLLSPGGSSFDQFESYEHRGNCFINAVKDLVKRK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBE_LACSA
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTENRQGIPLITGRFDSLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ALL5_BLOTA
Sequence: MKFAIVLIACFAASVLAQEHKPKKDDFRNEFDHLLIEQANHAIEKGEHQLLYLQHQLDELNENKSKELQEKIIRELDVVCAMIEGAQGALERELKRTDLNILERFNYEEAQTLSKILLKDLKETEQKVKDIQTQ
What are the official names of this protein?
Mite allergen Blo t 5.
What is the protein family that this protein belongs to?
Belongs to the mite group 5 allergen family.
Protein: TEG6_HHV1E
Sequence: MTATPLTNLFLRAPDITHVAPPYCLNATWQAETAMHTSKTDSACVAVRSYLVRASCETSGTIHCFFFAVYKDTHHTPPLITKLRNFADLVNHPPVLRELEDKRGVRLRCARPFSVGTIKDVSGSGASSAGEYTINGIVYHCHCRYPFSKTCWMGASAALQHLRSISSSGMAARAAEHRRVKIKIKA
What are the official names of this protein?
Tegument protein UL55.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL55 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus matrix.
Protein: RS6_XYLF2
Sequence: MGRHYEIVLLVHPDQSEQVQAMLERYKALIENGHGKIHRLEDWGRRQLAYPIQKLVKAHYLMMNIEVEQSVLNELVDLFRFNDAILRHLAIKRSGPDTEQSFIMKSKDDKGDKPERRRRDDDENGDVGVSNDSDNDGGNAEAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MEAK7_CHICK
Sequence: MGNAESNAYRNHLSRFLPEEQSDVDGLFDTLSGSSSSAAAKNGKAMKKTMTLEALKAYMREPLPEQMTVRLYNGMRSIDLTGKSSALSDHVAKEQFVIFMSNLLKGNADEKITIIMRMISTTEGPVKGKEIQEFTEDLIKSVVHVLSYRKELKGWTLENTRDSAGGIKALSSQLLSELKLADGTKAVSPQLMEMSFDRSVIEDWVYRVPQISAFLSVVLRQGLHVLHSLPDQTKDIVNLVPGCKGIKGRIVSLFDIPSIIYINSHLPAELQHKWRLLFSSKLHGESFSQLCAHIVNKGPCVVILKDTDGFIFGGFASHSWEVKPQFQGDNRCFLFSVFPSLAVYTYTGYNDHYMYLNHGQQTMPNGLGMGGQHDYFGLWVDSDYGKGHSKAKPRCTTYNSPQLSAKENFTLDALEVWAVGDMPESAETKGKKSILDVDPEAQALLEMTGKSRHSEGLREPIEDEDDDN
What is the function of this protein?
Activates an alternative mTOR signaling to regulate cell proliferation and migration.
What are the official names of this protein?
MTOR-associated protein MEAK7, MEAK7, TBC/LysM-associated domain-containing protein 1, TLD domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane. Cytoplasm. Lysosome.
Protein: AMPP3_MAGO7
Sequence: MASKNYDDVLKGKYPAKEHARRVVEVIRSSQPDVSGVLYLEGQKTKMIEDNDSEEHFRQRRYFYYLTGCELPDCYLTYDIATSRSTLYIPPVDPESVIWSGLPMSALEALQKYDVDEVRYTHEVNAALTSLAEAAPSSTVYAIPNQVSDSITFLGFGAKNFDVLKPAIERARVVKSDYEIALIAKANDISGAAHLAVLKRVRHVSNERELYATFLAECISRGAPHMAYHSIVAAGRAAATLHYVKNDEPTAGKLNLLLDAACELNCYASDITRTFPISGSFTPESRAIYDTVLRMQLETLAMLKEGVRWDDVHIHAHRVAIEGLLAAGIFKKGFSVDEILESRTSVAFFPHGLGHYLGMDTHDTGGNANYQDKDSMFRYLRVRGTLPAGSVITVEPGIYFCNFIIEPYLKDEKHSKYIDAAVLDKYWDVGGVRIEDNVVITKDGYDNLTTAVKDAKEMEKIISSS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase PEPP, Aminoacylproline aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: NDUA4_GORGO
Sequence: MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDKSKPEPWNKLGPNDQYKFYSVNVDYSKLKKERPDF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.  NDUFA4 is required for complex IV maintenance.
What are the official names of this protein?
Cytochrome c oxidase subunit NDUFA4.
What is the protein family that this protein belongs to?
Belongs to the complex IV NDUFA4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GAR1B_RAT
Sequence: MMTSVPPRKTWWKSKKTVKVRRSYSTFPSLNAWEKFRGLLPVDGETNPGVGLGVEEGLLCQMVHSPEFNLFPNSVVFESNFVQVRRSRDWKEIYKASNTMALGVTSSVPCLPLPNILLMARVIWHQGQSQTWNRPSTVPSINLKSILPLKFVELQIWDHHERILRLRTVTEKIYFLKLHPDHPETVFRFWIRLVQILHKGLSITTKDPTILVTHCLVPKSLCSPGGKSELVQKNSKGLQPSESLTHLMAQGESEALSQIFSDLHQQKQYSSSRSEKVQINKTSSEKATPCEDSIPCTCDLNWRDAFMFGEWERENPSGPQPHSLLSTLAASSRPRLSLIGGNSI
What is the function of this protein?
RAB2B effector protein required for accurate acrosome formation and normal male fertility.  In complex with RAB2A/RAB2B, seems to suppress excessive vesicle trafficking during acrosome formation.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 1B.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: CHK1_DROME
Sequence: MAATLTEAGTGPAATREFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRLVRRMTRFFVTTRWDDTIKRLVGTIERLGGYTCKFGDDGVVTVSTVDRNKLRLVFKAHIIEMDGKILVDCRLSKGCGLEFKRRFIKIKNALEDIVLKGPTTWPIAIATNSVP
What is the function of this protein?
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA.  May also negatively regulate cell cycle progression during unperturbed cell cycles.  May phosphorylate the CDC25 phosphatase stg, which promotes its degradation.  This results in increased inhibitory tyrosine phosphorylation of Cdk1-cyclin complexes and consequent inhibition of cell cycle progression.
What are the official names of this protein?
Serine/threonine-protein kinase grp, Chk1 homolog, Protein grapes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
Protein: CDPAS_METMJ
Sequence: MIPAYVPNSAAALFGGGTPIDLGRTFSDGRRVFGDGKTYRGFFGGVVSGVLVGLIEIWAATAFSLSALPQQTFLSVTLLATGALLGDLAKSFLKRRLGKDRGESWFLADQYDLVVGSFLLILIFDPQWLFGTITLPIAVWIVVMTPLLHRVVNIIGYYIGVKEVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEOB_ACTSZ
Sequence: MKRVLIMMLDSFGIGGAEDADKFGDKGANTLGHIASHQPSLNLPHLESLGLGLAAKESCGELPKHFQNQPHLIGGYAFAREISSGKDTTSGHWEIAGVPVLFDWGLFPDKQNSFPKPLLDRIVAKAGIKGYLGNCHSSGTVILDQLGEEHMKTGLPIFYTSADSVFQIAAHEETFGLNNLYELCEIVRTELEGYNIGRVIARPFIGNKAGAFKRTGNRRDYSVEPPAKTVLQKFIEEKEGMVVSVGKIADIYAHTGISKKVKATGLEELFDKTLEEVKSAGDNTIVFTNFVNFDADFGHRRDVTGYAKGLEYFDRRLPELLRLMKDDDLLIITADHGCDPTWQGSDHTREHIPVLMYGAQVPARFLGARETFADIGQTVAKYLGVSPMEYGTAII
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBL37_ARATH
Sequence: MKRRRKDLKQAAESEQEECQSIAQVVSLGDSDQIQPPPNKKEEEDICEYLLQNFDLDHVMEILMRFPLTSLTRFKCVSKQWSSLISSRYFCNLLYTTVTRQQPRLYMCLKDDGGHRVLLSISSPSRGNTSFVVVEQDLSIPGMGGFFLNVVRGLMCFSRRKKARIYNPSTKQLLTLPAIKSDIVAQQGQTKHHPRYYIGHDPVSDQYKLVCTVAISSLLPRLGNLKSEHWVFALEAGGSWKKVVPLENYRHHAPSTEGRSTSGSVVRYMAWPDNYNCVVVSFDIRSEQLTIIPVPREIHLDEVVPAVTMMADLIEYGGKIAIFYHTNLKDEGSADLWVLEDTGKSEWSKKTLVLQPCQRHLVEDIELIVKGTTQDGKVILAPVEMHSRFYILYYNLQSNDLRKVEIKGVPDSWFDKECYFDLNSMDKSESFIYLET
What are the official names of this protein?
F-box/LRR-repeat protein At2g40920.
Protein: Y334_ACTP2
Sequence: MELIIISGRSGSGKSVALRALEDVGYYCVDNLPLPLIPELAGFLSNSGRSAVVSLDIRNIPENPESIEALLEQLSKLTIQTKIIFLDCERNTLIRRYSDTRRLHPLSNKDLSLESAIDLENTLLEPLYQQANYIIDTTNISSHELAENLRGILRGSTDKALKIVFESFGFKYGLPADADYVFDVRFLPNPHWNPELRPMTGLEQPVIDFLERQTEVHNFIYQTRNYLEMWLPMLEKNNRSYLTIAIGCTGGKHRSVFIAEQLAKYFQSRDKDVQIRHRSLEKHHKK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein APL_0334.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RS181_MYCUA
Sequence: MAKSNKRRPAPEKPVKTRKCVFCAKKDQAIDYKDTALLRTYISERGKIRARRVTGNCVQHQRDIALAVKNAREVALLPFTSSAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EFG_SYNJA
Sequence: MARTVPLERVRNIGIAAHIDAGKTTTTERILFYSGLVHKLGEVHEGTTVTDWMAQERERGITITAAAITTRWTKRDPKNPSQPLAGAPEYTINIIDTPGHVDFTIEVERSMRVLDGVIAVFDSVGGVQPQSETVWRQANRYNVPRIAFVNKMDRMGANFLKVYNQIRERLKANAVPIQLPIGAEDEFRGIVDLVRLQANIYMDEIGKDIRPAPIPEEMKDLVAEYRAKLVEAVAETDEALMEKYFAEEDLSEADLMAGLRKGTISGQIVPMLCGSAFKNKGVQMLLDAVVDYLPSPIDIPAIKGVLPDGSEVSRKASDDEPFSALAFKLMSDKYGDLTFIRVYSGVLTKGTYVLNSTKNKKERISRLVVLKADERLDVDELRAGDLGAVLGLKDTTTGDTLCDENAPVILESLYIPEPVISVAVEPKTKADIDKLSKALQALAKEDPTFRVSVDPETNQTIISGMGELHLEILVDRMLREFNVEANVGNPQVAYRETIRKPVSRVEGKFIRQTGGRGQYGHVVIDLEPAEPGTGFEFVSKIVGGVIPKEYIPPAEQGIREACESGVLAGYPLIDIRVTLVDGSYHEVDSSEMAFKIAGSMALKEAARRANPVLLEPMMKVEVEVPEAFVGDVIGDINARRGQMEGMSTEGGISKVNAKVPLAEMFGYATDIRSKTQGRGIFTMEFSHYEEVPRSIAEAIIAKSKGSGVTN
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFTPA_MOUSE
Sequence: MSLGSLAFTLFLTVVAGIKCNGTEVCAGSPGIPGTPGNHGLPGRDGRDGIKGDPGPPGPMGPPGGMPGLPGRDGLPGAPGAPGEHGDKGEPGERGLPGFPAYLDEELQTASYEIKHQILQTMGVLSLQGSMLSVGDKVFSTNGQSVNFDTIREMCTRAGGHIAAPRNPEENEAIASITKKYNTYPYLGVIEGQTPGDFHYLDGASVNYTNWYPGEPRGRGKEKCVEMYTDGKWNDKGCLQYRLAICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (PubMed:25965346).
What are the official names of this protein?
Pulmonary surfactant-associated protein A, PSAP, PSP-A, SP-A.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.