PharMolix/UniProtQA huggingface dataset:
Protein: TIG_ACIBY
Sequence: MQVTTEAVSGVARRLNVSVPTSRINEQFEARLKRTAKTVKINGFRPGKVPANVVRREYGASIYQEVVNDIIRDSVFEAIQQEKINAVGMPNIEKVEHKEDALVFEATVEVYPEVEVKAFDGLEVERKTAEIKDADVDTMIENLQKQRQTWAVTKGMAKKDMQVTFDFEGSIDGEKFEGGSAEDFKLVLGSGRMIPGFEDGIIGMKAGEEKVIDVTFPEDYQAENLAGKAAQFKITVKQVEKPKLPEIDAEFLKIFGVSEEEGIEKLKADVRKNMEREVRNGLRNQVKQAAFDALVAANEIEVPAAMVAQEIDRQRQQMVQQFTQQFGGAGAQSFDKSMLPDELFKEQAERSVKLGVLVSKVLADAKLEVDQARVDAYIDDMASSYEDPTEVIEYFKNDAQQRAQIEAVVLEDQVVDHILASAKVTDKAVSYEDLLKEQQARRMG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HUNK_XENTR
Sequence: MPAAAGDGLGESPSRFLAGEKPPVQLAESFLPACVSSVSRETLRTFQHTKRVGSYLIGRKLGEGSFAKVREGLHVGTGEKVAIKVIDKKKAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCTGGNLMHKIYERKRIEEHEARKYIRQLILAVEHLHRAGVVHRDLKIENLLLDENNNIKLIDFGLSNCAGILGYTDPFSTQCGSPAYAAPELLARKKYGPKVDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKDMNPLPTHLSPAAISFLRSLLEPDPLKRPNIQQALANRWLNDNYHGKGLHTYPNRIHLEDLSQSVVLHMSEKLGYKHSDVINVILSNRACHTLAVYFLLNRKLENYLLNMRKPDINDNVCHKNQFHQLEKYKMNKNSYEERRSKDLEKRGEQQQQQQRAMQRKLEKCSPSHRQSNCLTPQGHISKGPVKERRSSKSERESFGGLSPFHEVRITKPGCMTSCSLEYLEMQSPDPRTPKIMRRQDSHSQETVNVNMGSRIRETHLNVVRSFESVNREDQIESLSPNHQYRVLGSPVSFSPRHSSERILSPIFQFDNTSPIKGHSNQASFTYDDKSSPSSPESMSPTSPHSPHSPSCNNNISGNLGSPNCVRSRGRFPMMGIGQMLRKRNQVVSPKAEKPLETRMPALHQMSPGYASFNSSDMNGFC
What are the official names of this protein?
Hormonally up-regulated neu tumor-associated kinase homolog, Serine/threonine-protein kinase MAK-V.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: ISPH_PECCP
Sequence: MQILLANPRGFCAGVDRAISIVERALELFGTPIYVRHEVVHNRYVVNGLRERGAIFIEQIEDVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASKKGIEAILIGHAGHPEVEGTMGQYSNADGGMYLVESPEDVWQLQVKDESNLCFMTQTTLSVDDTYAVIDALRERFPQIVGPRKDDICYATTNRQEAVRHLSDKADVVFVVGSKNSSNSNRLAELAQRAGKAAYLIDSAEDIQESWVEGASHVGVTAGASAPDILVQQVIQRLKALGGKVAVEMQGREENIVFEVPKELRVEVKQVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SECB_METPP
Sequence: MAEQDSNPVFQIQRVYLKDVSLEQPNSPQILLEQSQPQVDISLAVNAETVADGIYEVSVTATVTTKVADKTLFLCEAKQAGIFEIRNLPDGQTQPVLGIACPGIVYPYLRATVADIITRAGFPPVHLAEVNFQAMYEAQQQAAAQQQGAVSNGNGGSPIITNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVT1E_ARATH
Sequence: MKQNETFDQEREDLYHTFDEEDEESQTESSVPSTPLSRNRSEDVPVPWPRSYRQSMDLLTGVTPPTSTSFVSSFRQRRQSSVFGSFTSSPSKQQLLIDKDEIQSSVVSSIKSFLASHLQLSVPGDLLTPQENRSCTFSQSVLNGINVLCGVALLTMPYAVKEGGWLGLFILFSFGIITFYTGILLKRCLENSPGIHTYPDIGQAAFGTTGRILVSILLYVELYASCVEYIIMMSDNLSRMFPNTSLYINGFSLDSTQVFAITTTLIVLPTVWLKDLSLLSYLSAGGVISSILLALCLFWAGSVDGVGFHISGQALDITNIPVAIGIYGFGFGSHSVFPNIYSSMKEPSKFPTVLLISFAFCTLFYIAVAVCGFTMFGDAIQSQFTLNMPPHFTSSKIAVWTAVVTPMTKYALTITPVMLSLEELIPSSSRKMRSKGVSMLFRTILVLSTLVVALTVPFFATVAALIGSFIAMLIALIFPCLCYISIMKGRLTNFQIGICILIVIIGIVSGCCGTYSAIARLIGEMT
What are the official names of this protein?
Amino acid transporter AVT1E, AtAvt1E.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.5) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FMT_BORPA
Sequence: MRLVFAGTPEFARIALDALLAAGHDVPLVLTQPDRPAGRGLKLTPSPVKQAALAAGIGVAQPRSLRLDGRYPDEAAAARAQLERVAPDVMVVAAYGLILPQWTLDLPRLGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVTIMQMDAGLDTGDMLLERAVPIGAQQTAAQLHDELALAGGQAIVDALAALGQGGLAPRRQPDAGVTYAAKLDKAEAALDCSLPAAVLARRVRAFNPVPGATIRLPGLDDPVKVWRAQALEQAAGGPPGAVLRADAQGIDIATGQGVLRLLELQKAGGKRQPVDVFVRGWQP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GLUQ_PROM3
Sequence: MATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAWLLRVDDLDQPRNRVGAVESLQQDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYACRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLPSWRLRVSKEFSHTSGDVILRRADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDDQGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVLKSVLKP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: Y4701_DICDI
Sequence: MTKMLKFLFKNKINVELSIKQYKLNLRNPFGTAHSVTTTRTNALIEIKVEDIRGFGECGLPPKKPLCYLADYNDIETYFNSWIKEIDEKQKQQQQQQEESYHYDAFNKISQKEYFKELRKEMNGDYQQSVYQFLFECLDNCKENSKDYSYASRCAIEMALLDGWGKFLKQPIYKLINIPESESLKPFYYTISMCPTMEEIMDSTDFGSKYTGFLKIKLDADVEKGMNIIDSVQKRLLNNNSTRTISKISVDANSSWTPSVARKYLEKLSPMADLISMVEQPFPIETLKTVNKDQKIDIQHLNEWVSIKKEYQDKGLLIFADESICTEKDLDGLVQLVHGVNIKLEKTGGIRPGLSTLLKAKELGLKTWIGSMVASSLNVSAAAHLLCSLSDFGGDLDGGLLIDDATQLFENDAFQLLDNGLIKMNSNNYGVGVTLKK
What are the official names of this protein?
Enolase superfamily member DDB_G0284701.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: NUSB_BORGP
Sequence: MHEVRVLAFQKIYSIDINQSAMDDIFDIFSIEDKGLDIENESIKSFYSSLVNGTFNNLEYIDSLIKDISWNWSLDRMDKVDLAILRMGVYSLKFQNFENSKRALIDEAILIAKKYGSKNSDKFINGILDALLKNMENCIEKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NQRA_MARMS
Sequence: MYKITKGLDLPISGAPNQVIETAAAAKTVAVIGPDFHGMKPTMLVKEGDKVKKGQIIFTDKKTEGVNYTAPASGTVIEINRGERRVFQSLVIRVEGDESETFTSYSGSELKSLERSKVVDNLVNSGLWTSFRTRPFSKVPEIASVPNSIFVTAIDTNPLAASPEVVLADQAEAFADGLTVLTRLTEGKVFLCKASGAKIPTTSDVTVEEFSGVHPAGLAGTHIHFLDPVNDKKTVWSINYQDVVAIGKLFVTGELSVERVISVAGPQVKKPRLVRTQVGVSLNDLLAGELSEGDNRVISGSVLSGRKAFGPFAYLGRYHNQVSVLLEGRERQMMHYLRAGVEKHSIMNVFLSKLTGKKSFDMTTTTNGSDRTMLPLGNFERVMPLDILPTQLLRALVVNDTEQAQKLGALELDDEDLALCTYSCSGKFEYGPILRDCLTLIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: RL7_MICLC
Sequence: MAKLTTEELLAAFEELTLIELSEFIKAFEEKFDVTAAAPVAVAAAGGAAGGAEAAAAEEKDEFDVILEAAGDKKIGVIKEVRALTSLGLKEAKDLVDGAPKPILEGVNKETAEKAKEQLEGAGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NUOK_HELP2
Sequence: MIGLNHYLIVSGLLFCIGLAGMLKRKNILLLFFSTEIMLNAINIGFVAISKYTHNLDGQMFALFIIAIAASEVAIGLGLVILWFKKYKSLDIDSLNAMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_STAAC
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQISGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RUVC_FRATT
Sequence: MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RL17_LIGS1
Sequence: MAYRKLGRTSAHRKAMLRNLTTDLIVNEKIVTTETRAKEVRKFVEKMITLGKKGDLASRRRAAAFVMNVVADVKEENDDVVVQSALQKLFDDLAPRFAERNGGYTRILKMSERRGDAAKMVVLELVD
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL40_HALLT
Sequence: MASFDAAERRNLDRHICMRCNARNSPDADRCRKCGYTNLRPKAKERRAA
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: RS16_LEUMM
Sequence: MAVKIRLKRMGAKKRPFYRVVIADSRSPRDGRFIETVGTYNPISQPAEIKLDEEKILSWLGNGAQPSDTVRNLLSNAGILAKYNESKSGKKPAKKATTKEASAKKPTDKNTVAEIKAYLDAQGTAYTSSAKKADLLALV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HIS8_MYCSJ
Sequence: MTVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAAAELHRYPDRDAVALRSDLADYLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAIGFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREIAARRPDLVFVTSPNNPSGQSVPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGRLGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANSLSQLGFRVVPSDANFILFGEFADAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLTASARLVETELAATLGAS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RHG24_MOUSE
Sequence: MEERCESTESPQGQGRKNTKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFDVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEPQSKPQDGPNSNNNDGHKKATMGQLQNKENNNTKESPVRRCSWDKPESPQRSSVDNGSPTALSGSKTNSPRNSIHKLDISRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGVEKPQTTPNGSLQARRTSSLKSSGTKMGTHSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLRDNKQKEPAGESGQHNRLSTYDNVHQQFSSMSLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFYVGNFEDPVLDGPPQDDLSHPGDYENKSDRRSVGGRSSRATSSSDNSETFVGNTSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMLSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGDLTVEPRRSERGNTIWIQ
What is the function of this protein?
Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization.  Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state.  Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity.  Able to suppress RAC1 and CDC42 activity in vitro.  Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia.  Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 24, Rho-type GTPase-activating protein 24.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection. Note=Localizes to actin stress fibers. In migrating cells, localizes to membrane lamellae and protusions (By similarity).
Protein: RL22_BURVG
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SCX4_CENLI
Sequence: MNSLLMITACLALIGTVWAKEGYIVNYHDGCKYECYKLGDNDYCLRECKLRYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKRCNGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cll4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_GEOSW
Sequence: MKPFTVHKGKVAGIDRANIDTDQIIPKQFLKRIERTGFGKFLFYDWRYIDGEKPNPDFELNRPENEGATILVANENFGCGSSREHAPWALQDYGFQAIIAPSFADIFYNNCLKNGLLPIRLAKQDVEYLLRESTKADYELTISLEDQRVYDDSGFERTFDIDPYRKQLLLKGWDEIDLTFVYEPYIAEYEKKHCPMS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: HIS1_CORA7
Sequence: MIKIAVPNKGSLSEAALEILKEAGYKGRGHNKSLNVVDEENGVEFFFLRPKDIAIYVAQGVLDLGITGRDLALDSRAKFNEVLALNFGGSTFRYAAPAGEEWDVAKLQGKRIATSYPNVVRDHLAANGIDAEVIRLDGAVEISIHLGVADVIADVVSTGTTLRQQGLEPFGEPIVTSEAVVIKREGEDVTADENVVLSRIRGILNARHYVMLDYNVAEEKLPNVEAVTPGLTGPTISPLAREGWVAVRVMVPRKLANQVMDSLEELGAEAILASDLRIARF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARU_STAAC
Sequence: MDYQTFEKVNKFINVKAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
What is the function of this protein?
Positive regulator of RNAII and RNAIII in a cell density-dependent manner.  It can contribute to the expression of virulence genes controlled by agr.  May also regulate target genes via an agr-independent pathway (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarU, Staphylococcal accessory regulator U.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOT17_ARATH
Sequence: MESKTINDVVVSESNHELASSSPSEFEKNQKHYQEIIATLPHKDGWRPKDPFVEYGGHWWLQPLLEGLLHAQKFFKARPNDFFVCSYPKTGTTWLKALTFAIANRSKFDVSTNPLLKRNPHEFVPYIEIDFPFFPSVDVLKDEGNTLFSTHIPYDLLPESVVKSGCKIVYIWRDPKDTFVSMWTFAHKERSQQGPVVSIEEAFDKYCQGLSAYGPYLDHVLGYWKAYQANPDQILFLKYETMRADPLPYVKRLAEFMGYGFTKEEEEGNVVEKVVKLCSFETLKNLEANKGEKDREDRPAVYANSAYFRKGKVGDWQNYLTPEMVARIDGLMEEKFKGTGFLSSKS
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure.  Substrate preference is desulfo-benzyl glucosinolate > desulfo-6-methylthiohexyl glucosinolate.  Increased specific activity with increasing chain length of desulfo-glucosinolate derived from methionine.  Preferred substrate is desulfo-8-methylthiooctyl glucosinolate.
What are the official names of this protein?
Cytosolic sulfotransferase 17, AtSOT17, Desulfoglucosinolate sulfotransferase C, AtST5c.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT221_BOTFB
Sequence: MEDGGSGLRAPRYPAEDTSPTTDRELRGFFCYGLAAEVFAVCAVGSFLPVTLEQLAREQGVLFTDKITPCTAKNATAIANATVNALMSRAEGPDTHQCIVNVFGTELTTASFAMYTFSASVFMQALALVSVSSVADHGTWRKKLLAGFGFTGSVSAMLFLLVVPQIFVVGSLLTVICVVCLGCSFVILNSYLPLLVLNHPVVQSDEDHSIGSSSVPLRPISPGQSNRKPRDTLHQGADKEVNVGSKADSSDLQLSTQISSKGVGIGYMAAVSVQVVCILILYFMNKMGVSSTLPLRTVLFFVGSWWLTFTIPSVMWLRDRPGPPLPTALYEGRAFVRTCMSYTIFAWKSLWKTVKVAVKLRQVLIFLVAWFLLSDAVATISATAILFARTELQMGTVAVAVLSIVATSSGIVGATVWPIISKRFSLRTNHIIVCCLLLLELVPLYGLLGFIPFVQAWGVGGLQKWYEIYPLGIIHGMVMGGLSSYCRSFYGLLIPPGSEAAFYALFAITDKGSSAVGPAIVGKIVDATGQIRPAFGFLAVLIALPIPLIWMVDVEKGQEDAIRMAGLMKTTDDGHEDFDSIEGSSDGHEAEGLMRDHD
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: NTPPA_DEHMC
Sequence: MPDNPTGTLPEIILASASPRRRQILSEMGFVFSVCPSQAELYPDGSVAPAEFAVLNAQIKAKDIASKYSNGLIIAADTIVVDDFGILGKPSSKKVALNYLSRLGGKPHTVISSVCLLNAENGQIRSATCQSTLTMRPYTQAEAQRYVDSGLPMDKAGAYGIQDKEFNPAENIQGCYLNVVGLPACTLVRLINEMGFNPKLARNWKPEGDCTLCRIYRTEISRLR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CLOBJ
Sequence: MAGYRKLGRPTDQRKAMLRNLVTSFLKHGKIETTETRAKETRSIAEKMITLAKRGDLHARRQVLSFVTEETVVQRLFEEIAPKYAERNGGYTRIYKVGPRRGDGAEVVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MCA1A_ASPTN
Sequence: MQHHHHSSYGGGGGGYPGQAYRQQQPYYGQPSPQPYAQPPPPNYQRPSGYGPPPSGGHMYQQGPPAPYQQHNSYQGGHGRPAPPPTDPVAFGHGAPQGYNFQYSRCTGKRKALLIGINYFGQKGQLRGCINDVKNMSTYLNQNFGYAREDMVLLTDDQQNPMSQPTKANILRAMHWLVKDAQPNDSLFFHYSGHGGQTPDLDGDEDDGYDEVIYPVDFRVAGHIVDDEMHRIMVNPLKPGTRLTAIFDSCHSGSALDLPYIYSTQGILKEPNLAKEAGQGLLGVVSAYARGDMGSMVSTAVGFLKKAAKGDEAYERTKQTKTSPADVIMWSGSKDSQTSSDAQIQGQATGAMSWAFISALRKNPQQSYVQLLNSIRDELATKYSQKPQLSCSHPLDVNLLYVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: TRMFO_LACDA
Sequence: MTEKVTVIGAGLAGSEAAWQLAKRGIKVDLYEMRPKKMTPAHESGNFAELVCTNSMRSNQLSNAVGLLKEEMRQMDSLIMQAADACQVPAGGALAVDRELFSKYVTDKLTSLPEVIIHDEEITDLPSEGITVIATGPLTSDSLAEKIQDFEGAESLHFFDAAAPIIAADSIDMDIVYKKSRYDRGEAAYLNCPMTKEEYDRFANALVHAETAEIHGFENSEVFEGCMPIEVMAARGAKTLLFGPLKPVGLENPKDGKTPYAVVQLRQDNAAASMYNIVGFQTHLKYGEQKRVFQMIPGLENARFVRYGKMHRNTYMASPEVLKASYEAKKRPGLFFAGQMTGVEGYVESAGSGLVAGINAAREALGQETVEFPVTTALGSMAHYITTTDAKHFQPMNASFALIPGLEGKKIRNKRERHEKISERGLADLAAFKAEKLDD
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.