PharMolix/UniProtQA huggingface dataset:
Protein: PROA_HYDCU
Sequence: MDVKAYMQKLGQQAREASRQLMVATTRQKNTALLNIATALEEQAETLKTENAKDLEQGKANGLDAAMLDRLALTDKVINGMATGLRQIAALNDPIGEISDMNYLPSGIQVGKMRVPLGVVGIIYESRPNVTIDAAALCLKSGNAALLRGGSEAAYSNRALAKCIQSALHESGLLPTAVQVVETTDRAAVGEMIAMPEYVDVIIPRGGKGLIERISEGAKVPVIKHLDGICHVYIDDDADADKATRVAFNAKTHRYGVCNAMETLLIADSRAAEILPGLVELYEEKGVELRGCEQTRAICDMKAATEEDWATEYLAPILSIKVVDDVDEAIDHITQYSSGHTESIITENLTTSRQFLARVDSSSVMVNASTRFADGFEYGLGAEIGISTDKFHARGPVGLEGLTSQKYIVLGDGTIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_ARTS2
Sequence: MIPGEYVLGSTPVVINAGRDAIDVVVVNTGDRPVQVGSHYHFAEANAALAFDRAAAYGRRLDIPAGTAARFEPGDSKTVRLIELAGSREVYGLSNAVNGTLDAGNARQEAKTEAK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B_ONCMY
Sequence: MPEPAKSAPKKGSKKAVTKTAGKGGKKRKRSRKESYAIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGESSRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS4_CITBB
Sequence: MARYTGPSCRLCRREGSELFLKGERCYTDKCAIKRRSYPPGQHGQGRIKVSDYGVQLREKQKVRRIYGILENQFRGYFETADRMKGVTGENLLFILERRLDNVAYRLGFATSRDEARQLVRHGHFTLNGKKVNIPSLQVKAGDVLQLREKSRKVAAISESLEGVVRRGIPQWLELEKDAFKGTVKAMPVREDITMPIQEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CAS6_PYRFU
Sequence: MRFLIRLVPEDKDRAFKVPYNHQYYLQGLIYNAIKSSNPKLATYLHEVKGPKLFTYSLFMAEKREHPKGLPYFLGYKKGFFYFSTCVPEIAEALVNGLLMNPEVRLWDERFYLHEIKVLREPKKFNGSTFVTLSPIAVTVVRKGKSYDVPPMEKEFYSIIKDDLQDKYVMAYGDKPPSEFEMEVLIAKPKRFRIKPGIYQTAWHLVFRAYGNDDLLKVGYEVGFGEKNSLGFGMVKVEGNKTTKEAEEQEKITFNSREELKTGV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism.  This protein processes pre-crRNA into individual crRNA units, with an 8-nt 5'-repeat DNA tag that may help other proteins recognize the crRNA.  Further processing occurs at their 3' termini in this organism.  Generates a 5'-hydroxy and 2',3'-cyclic phosphodiester.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas6.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Protein: AROC_METM5
Sequence: MNTFGDNFRVTTWGESHGKALGAVIDGCPSNLPISEEDIQNELNRRRPGYSIFSTPRKEEDKLEILSGIFEGKTTGTPISGLVFNKGQKSKDYSKIKNTPRPGHADLNYFLKYGNYDYRGGGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGKINGDFDYYKNPEFFESNSNIEKLFEKIENNPLRCPSKNSDEMKDYVLDAMDKQDSVGGIIEIIIKGIPQGVGNPVFNKLEGKLGSAFIGINAVKGFEIGRGFESSELYGSEMNDSYYMNKDSIKGKTNNTGGIIGGISTGSPVVLRVSIKPTPSISKIQESVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVADLMISSGYIDPCRI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RMAR_NAUCC
Sequence: MKLNILKLLNNNNNKNMLLKNMLLKMNINNNNMNTNNNNMKYMNNKLQSINNMNNWSLQMYNYNKNNELNMMMMMNMMNKLLYKLMNMIMINNMTMNVNNKNNNNIIMMKPMYQYMMNKLNIKFYYYINNNNMNTNYYMNMLYKLMNTLNNNNNMYMNNMNNIMSMYINKNINIEMIKLNYVYNNKDIMNKYLSTMDIDTLNNNSTMNLLNNMMTKMNNNNIIMNYMNNMNNMRNNKYINNMSSNYIMNMLMYKYLTGWTILLKGRLNKNMTRTNKYILYNGSNKMNMYMKNNYKLNYISNNHFINNINNVNKNGKYNIKVKLSYI
What is the function of this protein?
Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
What are the official names of this protein?
Ribosomal protein VAR1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NOP12_EMENI
Sequence: MGKKSKSQKEAPATESAGSLPFLGGNVSVDPSLASLFEQSAGPVKVPEVPRLGAAPKTKITDVEKDEEESSSAGNDSASEDQFMEDAPESPDAAEEAVQAVPEPPSRKRKRAAGEDLEESYMRRLAKEEQKEQKKRRAERSSSLEEESEDGEKESPQSEDGESEDEGADIPKHEALAGAANDDDELSKSNRTVFLGNVSTKAITSKSAKKELMKHLSSFLSTLPESTGPHKIDSIRFRSTAFASGGKIPKRAAFAKQEIHDDTTPSTNAYAVYSTAQAAKKAPAALNGTVVLDRHLRVDNVAHPAKVDHKRCVFVGNLDFIDNETGTEEGEKKKKNRPPADVEEGLWRTFNAHTKASQSGPAGRGNVESVRVVRDRSTRVGKGFAYVQFYDQNCVEEALLLNDKRFPPLLPRKLRVVRAKKVAKKSVETTGAPKGSDRTLQGRAGKLLGRSSEARLKAAAKKSISQSSLVFEGNRATADGSSRIRVRTKSRGSKAKKDSRSKKRAAAYKAAGGKKAKIGK
What is the function of this protein?
Involved in pre-25S rRNA processing.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SNL6_ARATH
Sequence: MRDLLLGTTIPSYFSWLGLFPRFLVWFGFLKASFFCSSRNQSAGESGRRLKMKRAREDVHTDTQKRKPEVSSRGETNKLPRTIDALTYLKAVKDIFHDNKEKYESFLELMKEFKAQTIDTNGVIERIKVLFKGYRDLLLGFNTFLPKGYKITLLPEEEKPKIRVDFKDAIGFVTKIKTRFGDDEHAYKRFLDILNLYRKEKKSISEVYEEVTMLFKGHEDLLMEFVNFLPNCPESAPSTKNAVPRHKGTATTAMHSDKKRKQRCKLEDYSGHSDQREDGDENLVTCSADSPVGEGQPGYFRDYENREDTETDTADRTEKSAASGSQDIGNHKSTTKYVGTPINELDLSECTQCTPSYRLLPKDYAVEIPSYRNTLGKKTLNDHLVSVTSGSEDYSFSHMRKNQYEESLFRCEDDRYEMDMLLGSVSSAIKQVEILLEKMNNNTISVDSTICIEKHLSAMNLRCIERLYGDNGLDVMDLLKKNMHSALPVILTRLKQKQEEWARCHSDFQKVWAEVYAKNHHKSLDHRSFYFKQQDSKNLSTKCLVAEVKDISEKKHQEDLLQAIAVRVMPLFTPDLEFNYCDTQIHEDLYLLIKYYCEEICATEQSDKVMKLWITFLEPIFGILSRSQDNLALEDVSKLKNNRELQDACLAVKETASGSNRKHPISPKRLSKDNTKMQGSSSREDVSANIKVKTAQPDKLQDDAAMTNEVIQSSKFVSPKNDQIMEDEGNHMVNAASVEKHELEEGELSPTASREQSNFEVNGQNAFKPLQKVTDNVRSNKDKQSCDKKGAKNKTRAEDDKQENCHKLSENNKTASEMLVSGTKVSCHEENNRVMNCNGRGSVAGEMANGNQGEDGSFAFSERFLQTVKPVAKHLSWPLQASETCSQNDSQVFYGNDSYYVLFRLHQMLYERIQTAKKHSEKKWKAADNTTPDSYPRFMDALYNLLDGSIDNTKFEDECRAIFGAQSYVLFTLDKLVQKFVKHLHSVASDETDTKLLQLHAYENYRKPGKFFDLVYHENACALLHEANIYRIRYSSEGTRLSIQLMNSGNNQLEVMGVAMEPAFADYLQNKCLKSVNDEENHGLFLNRNKKKFTSLDESRGMPVAMERLNIINEMECRMACSSSKVKYVANTSDLLYRSKQGKPNSRVSEILKQRRISRFHIMLNCRLCALPL
What is the function of this protein?
Acts as a transcriptional repressor.  Plays roles in regulating gene expression and genome stability (By similarity).
What are the official names of this protein?
Paired amphipathic helix protein Sin3-like 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: GBRP_RAT
Sequence: MSYSLYLAFVCLNLLAQRMCIQGNQFNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEGNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAVKDRGPAKDSEEVNITNIINSSISSFKRKISFASIEISGDNVNYSDLTMKASDKFKFVFREKIGRIIDYFTIQNPSNVDRYSKLLFPLIFMLANVFYWAYYMYF
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.  In the uterus, the function of the receptor appears to be related to tissue contractility.  The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit pi, GABA(A) receptor subunit pi.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: TARI2_STAA8
Sequence: MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: SPEE_YERPE
Sequence: MSQKELWYETLHANFGQYFSVENVLFREKTEHQDLVIFENPELGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQITMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPIGPGESLFTSVFYEGCARSLNEGGIFVAQNGVCFLQQDEAVNSHNKLSHYFSDVSFYQAAIPTYYGGIMTFAWATQNPALRQLDLATLQNRFAQAGLACRYYNPAIHVGSFALPQYLLDALTTIPKVIGVDSSE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_CYAP4
Sequence: MATSDTIGDMLTRIRNANLARHPTTEVPATRMTRSIAQVLKNEGFINDFEEIGDGVKLNLVISLKYRGKQRQPTITALKRISKPGLRVYSNRRELPRVLGGIGIAIISTSSGIMTDRDARRSGVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CAH1_CHIHA
Sequence: AHAWGYGPTDGPDKWVSNFPIADGPRQSPIDILPGGASYDSGLKPLSLKYDPSNCLEILNNGHSFQVTFADDSDSSTLKEGPISGVYRLKQFHFHWGASNDKGSEHTVAGTKYPAELHLVHWNTKYPSFGEAASKPDGLAVVGVFLKIGDANASLQKVLDAFNDIRAKGKQTSFADFDPSTLLPGCLDYWTYDGSLTTPPLLESVTWIVCKEPISVSCEQMAKFRSLLFSAEGEPECCMVDNYRPPQPLKGRHVRASFQ
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase I, CA-I, Ice-CA.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y015_CORGL
Sequence: MSTNLLESTPPFTQLRTGVLQKYTPGLLLCSIAVLIAMIVNHFFSGVSPLIVAIILGIILTNLIQLPASTSPGITLASKKLLRLGIVFLGLQLVFSDILSLGFPMLAVIVCIVAGGIFGTILMGHLLRMKPTQVLLIACGFSICGAAAVAGVEGVTDSEEEEVVTAVALVVIFGTLMIPFIPFATKVLGLSPEIGGMWAGGSIHEIAQVVAAGGVIGGGALGVAVVVKLARVLLLAPIAAILSFRQRRQGYTSPDGKRPPVVPLFILGFLAMVVLRSTVALPDEVIAAGGFLQTALLSAAMFGLGCGVKIQNLIHVGVKPFILAFGSTTLVTSIALAGTLLTHLG
What are the official names of this protein?
UPF0324 membrane protein Cgl0015/cg0018.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXK_KLEP7
Sequence: MIARIWSGESPLWRLLLPLSWLYGLVSGVIRLSYQLGWQKAWRAPVPVVVVGNLTAGGNGKTPVVIWLVEQLQQRGIRVGVVSRGYGGKAERYPLVLDDRTSTALAGDEPVLIHQRTGAPVAVAPLRSDAVKALLSAHDLQMIVTDDGLQHYKLARDREIVVIDGVRRFGNGWWLPAGPMRERASRLQSVDAVIVNGGVARPGEIPMRLRPGMAVNLLTGERRDVSTFTNVVAMAGIGHPPRFFATLESCGVQPVKTVALADHQALSQADVAALVTADQTLLMTEKDAVKCRDFAAANWWYLPVDAIMADERAQRLLADLATLAQR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL14_SYNP2
Sequence: MIQQQTYLNVADNSGARKLMCLRVLSTGNCRYGGIGDQIIAVVKEAIPNMGVKKSDVVRAVIVRTRQPLRRASGMSIRFDDNAAVIINAEGNPKGTRVFGPVARELRDKNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RS21_STAHJ
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS13_PSECP
Sequence: MARLAGVDIPREKRLEIALTYIYGVGKTRAHETLAATGISADVRVKDLTDAQLVELRDYIEGNYKVEGDLRREVAADIRRKVEIGSYEGLRHRKGLPVRGQRTKTNARTRKGPKRTVAGKKKAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NIC3_ARATH
Sequence: MASSSTRKYETRKRDPNSKIAALLVIDMQNHFSSMAKPILNNVLTTIDICRRASVPVFFTRHNHKSPTDHGMLGEWCNGDVILDGTTDSEIIQEIQGQVTGPDEMVEKNTYSAFNKTRLQENLEKIGVKEVIVIGVMTNLCCETTAREAFIKGFRVFFSTDATATFNEELHEATLMNLAFGFAYLVDCDKLRRSLLGN
What is the function of this protein?
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway.  Prevents the accumulation of intracellular nicotinamide, a known inhibitor of poly(ADP-ribose) polymerases (PARP enzymes).
What are the official names of this protein?
Nicotinamidase 3, AtNIC3, Nicotinamide deamidase 3.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: DER_CELJU
Sequence: MIPVIALVGRPNVGKSTLFNRLTNSRDALVADYPGLTRDRKYGEARLENRRFIVIDTGGISGEEEGIDSAMAGQSLLAIQEADIVLFIVDSRVGLNPADELIARHLRVHNKKTYVVANKIDGMDPDIALAPFYELGMGEVHPTTATHGRGVRSLMEDVLAEYPEIPEEEQQGEATGIKIAIVGRPNVGKSTLVNRLLGEDRVVVYDQPGTTRDSIYINYTRFDKPYTLIDTAGVRRRKNIDLAVEKFSIVKTMQAIADANVVILVMDASEGIVEQDLHLMGTAIEAGRALVIALNKWDGLDESHKYYVKNELERRLRFVDFANIHFISALHGTGVGNLYKSIEQAYQSATDRFSTNYLTRILQDAVREHQPPMINGRRIKLRYAHPGGHNPPVIIVHGNQTDDVPGHYVKYLEKTYRRVLDLHGTPIRIEFRTTDNPYEARKKSMTRQQFIQKRRKEERDRNNPRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL11_STRU0
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVITVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTRAQVQEIAETKMPDLNAANLESAMRMIEGTARSMGFTITD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: INSM1_MOUSE
Sequence: MPRGFLVKRSKKSTPVSYRVRGGEDSDRALLLSPGCGGARAEPPVPSPGPLPPPPPPALAERAHAALAAALACAPGPPPPPPPGPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFPTPAALLAGGGSGANGAGGGGGGTCGGDALLFAPAELKMGTAFSAGAEAARGPGTGPPLSPAAALRPPGKRPAPPAAVATEPPAKAAKAPSAKKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGATRPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPVPAAARAPEPEAATRAEAREAAGGGSSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPPPPPPPPAEDILAFYAGPDEKAPQEASGDGEAAGVLGLSATAQCHLCPVCGETFPSKGAQERHLRLLHAAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC
What is the function of this protein?
Sequence-specific DNA-binding transcriptional regulator that plays a key role in neurogenesis and neuroendocrine cell differentiation during embryonic and/or fetal development.  Binds to the consensus sequence 5'-[TG][TC][TC][TT][GA]GGG[CG]A-3' in target promoters.  Acts as a transcriptional repressor of NEUROD1 and INS expression via its interaction with cyclin CCND1 in a cell cycle-independent manner.  Negatively regulates skeletal muscle-specific gene expression in endocrine cells of the pituitary by inhibiting the Notch signaling pathway.  Represses target gene transcription by recruiting chromatin-modifying factors, such as HDAC1, HDAC2, HDAC3, KDM1A and RCOR1 histone deacetylases.  Binds to its own promoter, suggesting autoregulation as a self-control feedback mechanism.  Competes with histone H3 for the same binding site on the histone demethylase complex formed by KDM1A and RCOR1, and thereby inhibits demethylation of histone H3 at 'Lys-4' (By similarity).  Promotes the generation and expansion of neuronal basal progenitor cells in the developing neocortex.  Involved in the differentiation of endocrine cells of the developing anterior pituitary gland, of the pancreas and intestine, and of sympatho-adrenal cells in the peripheral nervous system.  Promotes cell cycle signaling arrest and inhibition of cellular proliferation.
What are the official names of this protein?
Insulinoma-associated protein 1, Zinc finger protein IA-1.
What is the protein family that this protein belongs to?
Belongs to the INSM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDHK2_SYNY3
Sequence: MSTSTHALTLQNPIQAPQVTKELSENVILTCLDDIYNWARLSTLYPMMFGTACCFMEFMAAFGPRFDLERFGSIPRATPRQADLMITAGTITMKYAPALVQLYEQIPEPKYVIAMGACTITAGMFSADSPTAVRGVDKLIPVDVYIPGCPPRPEAVIDGIIKLRKKVAGESRQDYTEDLQTHRFHAVRHRMKPVSPILTGQYLRHHEDLTPHHDPLLIK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K 2, NAD(P)H dehydrogenase I subunit K 2, NDH-1 subunit K 2, NDH-K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS20_DESOH
Sequence: MANHKSSLKRAKQDIVRNTRNKSRKTALKTITKKVDALVADGAAEDAKTTLLAAQKLFDQTAAKGTIHKKTASRKISRLTRRVNAAAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS10_HYPBU
Sequence: MVQKAEIKLWSTNVESLNQVVEQIKAIAKKTGVRMRGPIPLPTRRLIVPTLKLPHGEGSKKWDKWELRIHKRLVILDADERVIRQIMRVRVPEDVYIEIRLR
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ATPH_LIRTU
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RBFA_RICBR
Sequence: MKKLTSENSHRQQKVASIINEALIEILHRGKMLDPRLYDCPLTITKIIVTADLKIANCYFLPFNTKLTPQEITESLNNSKNAIRNFVTGKINMKYSPDIRFHYDHGFDNALKVEQLLKDTNNI
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND1_FRACC
Sequence: MIYREMLKSKIHRAVVRQADLHYVGSITIDATLMAAAGLWPGEKVDVLDITNGARLSTYVIEGEADSGTIGINGAAAHLISPGDLVIIVGYALMAEEDARSYQPNVVFVNGDNQLVRMGTDPAEAYDGVGLVRGDTNSPQPSLSEQAGDPRRAQ
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase 1, Aspartate alpha-decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_MYCSS
Sequence: MSIRERHLSHGAPSRIRTTVLAYLALTKPRVIELLLVTAIPAMLLADRGSVDPLLILNTLIGGMLAAAGANTLNCVADADIDKKMKRTARRPLARDTVPTRNALIFGLVLSVGSFFWLWGTSNLLSGLLAVATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLALALATGWLYASVAVLAGTWFLVMAHQLYNGVKRGEPVKPLRLFLQSNNYLAVVFAALAVDSVLALPTLLGS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.