PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_CLOK1
Sequence: MEFKHIPVLLKETIDSLNIKQDGVYVDCTLGGGGHSLEILKRLSDKGKLIAIDQDISAINWSEERLKNFKNIIYVHDNFYNIQQILKELKIDKVDGIIMDLGVSSYQLDEGKRGFSYMKDAPLDMRMNRDSSLSAYEIVNQYNEEELCRIIRDYGEENFSRRISKFIVKAREESPISTTLQLVGIIKKAIPLKFQKEGHPAKRTFQAIRIEVNEELKILDKAVEDGVANLNTGGRIAIITFHSLEDRIIKSKFKMLENPCTCPADFPICICGKKPIVKIVNKKPIVPTEEEKSINPRSKSSKLRIAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_YERPE
Sequence: MTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTWAFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCVIMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGYELSS
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA2_MOUSE
Sequence: MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGGFRRIVRLVGIIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPAVAE
What is the function of this protein?
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger.  The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
What are the official names of this protein?
Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2, Cyclic nucleotide-gated channel alpha-2, CNG channel alpha-2, CNG-2, CNG2.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRD_STUS1
Sequence: MYNLARQLLFKLSPETSHELSLELIGAGGRLGLNAMLSKPPASLPVRVMGLDFPNPVGLAAGLDKNGEAIRGLSQLGFGFIEVGTVTPRPQPGNPKPRIFRLPEAEAIINRMGFNNHGVDALLARVEAARFKGVLGINIGKNFDTPVERADEDYLLCLDKVYHHASYVTVNVSSPNTPGLRSLQFGDSLKQLLDALRLRREDLEIMHGKRVPLAIKIAPDMTDEETALVGEAVFQAGMDAIIATNTTLGREGVAGLAHADEAGGLSGAPVRDKSTHTVKVLAQTLGGRLPIIAVGGITEGRHAAEKIEAGASLVQLYSGFIYKGPALIREAVDAIAALRSQAK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
Protein: YIIX_ECOLI
Sequence: MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATHTDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQKLAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSSPQVQAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW
What are the official names of this protein?
Uncharacterized protein YiiX.
What is the protein family that this protein belongs to?
To E.coli YebB.
Protein: PSAA_NICTO
Sequence: MIIRSPEPEVKILVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYADFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGATAPGATASTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSVSDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GL33_ARATH
Sequence: MKMIIQIFFIISLISTISFASVQDFCVADPKGPQSPSGYSCKNPDQVTENDFAFTGLGTAGNTSNIIKAAVTPAFAPAYAGINGLGVSLARLDLAGGGVIPLHTHPGASEVLVVIQGTICAGFISSANKVYLKTLNRGDSMVFPQGLLHFQLNSGKGPALAFVAFGSSSPGLQILPFALFANDLPSELVEATTFLSDAEVKKLKGVLGGTN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 3 member 3, AtGER3, AtGLP2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: YBEY_XANCP
Sequence: MTKGPVRLDVGVSYALPRTGLPSSVSFRKWVAAALKGRIREADLAVRVVDEKEGCSLNHHYRGKDYATNVLSFPAEMPQGLPKGVKMPLLGDLVICAPVVAREAAEQGKSLSAHYAHLTVHGTLHLLGWDHEDDKEADAMEQLEREILAELGIDDPYAGER
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC2_SULTO
Sequence: MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQEEKLYGILDENSKVIIANNRAEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEKKYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGSFAFIIGDKKRPNRIYIAQNFKPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKKVLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDTDLFKIIGHTTLLKGGGEIVKDRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIASGINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMPVGNLVKHEIVKLGVEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase 2, 7-cyano-7-carbaguanine synthase 2, Archaeosine biosynthesis protein QueC 2, PreQ(0) synthase 2.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MUTS_PSEA7
Sequence: MTDLSQHTPMMQQYFKLKHQHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSGGKAIPMAGIPFHSAEGYLAKLVKLGESVAICEQIGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLLAAILGDERLFGLAVLDITSGRFSVQEIKGWETLLAELERLNPAELLIPDDWPQGLPAEKRRGVRRRAPWDFDRDSAHKSLCQQFGTQDLKGFGCQNLTLAIGAAGCLLAYAKETQRTALPHLRSLRHDRLDDTVILDGASRRNLELDINLSGGRENTLQSVVDRCQTAMASRLMSRWLNRPLRDRAVLEARQESIACLLERYRFENLQPQLKEIGDLERILARIGLRNARPRDLARLRDALAALPDLQNAMTELEAPHLQALATTIGTYPELAELLAKAIIDNPPAVIRDGGVIKTGYDAELDELQALSENAGQFLMDLEAREKARTGLPNLKVGYNRIHGYFIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAQSRALAREKALYEELLERLIGHLAPLQDSASALAELDVLANLAERALNLDLNRPRFVEHTCLHIEQGRHPVVEQVLETPFVANDLALDADTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAARCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATDKSLVLMDEVGRGTSTFDGLSLAWAAAEDLARTRAFTLFATHYFELTVLPESQPAVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPSPVIQRAREHLKRLETTSLPHEVPSQQSGKPASPMQSDLFASLPHPVIDELSRINPDDISPRQALDLLYAWKMRV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GAG_SCVLA
Sequence: MLRFVTKNSQDKSSDLFSICSDRGTFVAHNRVRTDFKFDNLVFNRVYGVSQKFTLVGNPTVCFNEGSSYLEGIAKKYLTLDGGLAIDNVLNELRSTCGIPGNAVASHAYNITSWRWYDNHVALLMNMLRAYHLQVLTEQGQYSAGDIPMYHDGHVKIKLPVTIDDTAGPTQFAWPSDRSTDSYPDWAQFSESFPSIDVPYLDVRPLTVTEVNFVLMMMSKWHRRTNLAIDYEAPQLADKFAYRHALTVQDADEWIEGDRTDDQFRPPSSKVMLSALRKYVNHNRLYNQFYTAAQLLAQIMMKPVPNCAEGYAWLMHDALVNIPKFGSIRGRYPFLLSGDAALIQATALEDWSAIMAKPELVFTYAMQVSVALNTGLYLRRVKKTGFGTTIDDSYEDGAFLQPETFVQAALACCTGQDAPLNGMSDVYVTYPDLLEFDAVTQVPITVIEPAGYNIVDDHLVVVGVPVACSPYMIFPVAAFDTANPYCGNFVIKAANKYLRKGAVYDKLEAWKLAWALRVAGYDTHFKVYGDTHGLTKFYADNGDTWTHIPEFVTDGDVMEVFVTAIERRARHFVELPRLNSPAFFRSVEVSTTIYDTHVQAGAHAVYHASRINLDYVKPVSTGIQVINAGELKNYWGSVRRTQQGLGVVGLTMPAVMPTGEPTAGAAHEELIEQADNVLVE
What is the function of this protein?
Binds and removes 5' cap structures from cellular mRNA.  Forms a covalent bond with m7GMP through His-154 of the capsid protein while releasing the mRNA body.
What are the official names of this protein?
Major capsid protein, Gag protein, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the totivirus major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: GALK1_BOVIN
Sequence: MAASEQPQAGELLAKARRAFLEEFGAEPELAVSAPGRVNLIGEHTDYNRGLVLPMALELVTVLVGSPRVDGLVSLLTTSEDADEPRRLQFPLPTSQRPLEPGTPHWANYVKGVIQHYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQRAEHSFAGVPCGIMDQLIALLGQRGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLGSSEYPLRRRQCEEVARALGKESLREVQLEELEAGRDLMSTEAFRRARHVVGEIQRTAQAAAALRRGDYRAFGRLMVESHHSLRDDYEVSCPELDQLVEAALSAPGVYGSRMTGGGFGGCTVTLLEASAAPRVMQHIQEQYHGTATFYLSQAADGAKVLHF
What is the function of this protein?
Catalyzes the transfer of a phosphate from ATP to alpha-D-galactose and participates in the first committed step in the catabolism of galactose.
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: WP1_PEROL
Sequence: MEDEGAGG
What is the function of this protein?
Is a major protein component of the cell wall.  May play a key role in the organization of the cell wall and in promoting the survival of this parasite.
What are the official names of this protein?
Wall protein 1, PWP-1.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Disulfide-linked to other cell wall components.
Protein: HEXA2_DICDI
Sequence: MINKFLTIFLIFSIVIIKVLSQSSNEQPLNVVPYPQEVTMIGCNIPLSVGSISIKSNIESTILSISISRYQSLFFPFVSNNVLKDSSSNIELSLIIASDDETLELGIDESYFLLVNQDTYQIKANTIYGAMRGLETFKQMVVYDVVENSYSLTCAEVVDYPTYQWRGLLVDNARHFLPKNMVLHIIDSMGYNKFNTMHWHLIDTVAFPVESKTYPKLTEALLGPGAIITHDDILEVVAYAKTYGIRVIPEFDVPGHSASWGVGYPELLSNCPGYPQSSIPLDCSNPYTYSFLENFFSEIAPLFQDSYFHTGGDELVIDCWANDTSIQKWMKTNNYNTSDAFQYFEDQLDVILKSINRTKIAWNDVLQHGVKFDKETTLVQTWTNINDLRDVLAAGYKTITSFFFYLDRQSPTGNHYHYEWQDTWEDFYASDPRLNITSNAENILGGEATMFGEQVSTVNWDARVWPRAIGISERLWSATEINNITLALPRIGQFSCDMSRRGISSGPLFPDFCSLPDDLSFSFKPVYQLSKDEIKLILKKK
What is the function of this protein?
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines.
What are the official names of this protein?
Beta-hexosaminidase subunit A2, Beta-N-acetylhexosaminidase subunit A2, N-acetyl-beta-glucosaminidase subunit A2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: MDTQ_SHIFL
Sequence: MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTALPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQDGPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNRAEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIATDRQLYQNGITSSVDGVETDINASKTRQQLNDVAGKMKIIEARLNALTNHQTKSLKLKPVALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAVNDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRERANGLLLQGQWLDASIRLTGALGGGYKR
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Putative multidrug resistance outer membrane protein MdtQ.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ESXP_MYCTU
Sequence: MATRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMAQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxP.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: MATK_PRIVE
Sequence: MEEFKRYLELDKSKSQQHDFLYPLLFQEYIYGLAHHNQSLTRSSSLELEKTGFDNNFSLLIVKRLITQMGRQNHLSFFTNDSNQNPFLGHNTTLYSKILLDGFVVVLEIPFSIRVISSLECKEIVKSHNLRSIHSIFPFLEDKFTHLNYVLDFLIPHFIHLEILVQTLRYWVKDASSLHLLRALIHKYHNWNNIITLKKSSFSFSKRNKRFLFFLYNFHVYEYESIFTFLRNQSSHLKSNSYRPFLDRIYFYEKRDHFLEIFTNYFQAILCSFKDPFMHYVRYQGKALLASKGVFLLINKWNSYLVNFWQCYFYTWSQPGRIQINKLSNHSLDLLGYLSSVRLTSSMVRNQMLENVFLIANASKKLNTIVPIIPLIGSLSKAKFCNPLGHPISKPVWADLSDSDIIDRFGRIYRNISHYYSGSSKKMSLYRIKYIIRLSCARTLARKHKSTVRAFLKRTGSELLEEFFMEEERIFSLTFPKISSTSTSGGLYRNPIWYLDIFCINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GDU3_ARATH
Sequence: MEGRQYYPPRENVEGNRTTMGGGPHSPWHSPVPYLFGGLAAMLGLIAFALLILACSYWRLSGYLDGEENQSRERDLEVGDVKPDKTAVKPVALPEKFLVIMAGNVKPTYLATPSVKTCTCDDDDDEDDDVEGSDQVVPRSSESNGETH
What is the function of this protein?
Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism.  Stimulates amino acid export by activating nonselective amino acid facilitators.  Acts upstream genes involved in the salicylic acid (SA) pathway and in the geminivirus-host interaction.
What are the official names of this protein?
Protein GLUTAMINE DUMPER 3, Protein LESS SUSCEPTIBLE TO BSCTV 1, Protein LBS1.
What is the protein family that this protein belongs to?
Belongs to the GLUTAMINE DUMPER 1 (TC 9.B.60) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SRRM4_HUMAN
Sequence: MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR
What is the function of this protein?
Splicing factor specifically required for neural cell differentiation.  Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation.  Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2.  Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity).  Promotes alternative splicing of REST transcripts to produce REST isoform 3 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:30684677).  Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system.  Regulates alternative splicing events in genes with important neuronal functions (By similarity).
What are the official names of this protein?
Serine/arginine repetitive matrix protein 4, Medulloblastoma antigen MU-MB-2.76, Neural-specific serine/arginine repetitive splicing factor of 100 kDa, Neural-specific SR-related protein of 100 kDa, nSR100.
What is the protein family that this protein belongs to?
Belongs to the nSR100 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CALC_ANGJA
Sequence: CSNLSTCVLGKLSQELHKLQTYPRTDVGAGTP
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HPRT_PANTR
Sequence: MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDTKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_BORA1
Sequence: MTASPISVIASANRLVAKVGSSLVTNEGRGLDRAAVAHWAAQIAALHKQGRQVVLVSSGAIAEGMARLGWRKRPSVMHELQAAAAVGQMGLCQAYEAAFAEHGLRTAQILLTHEDLADRHRYLNARSTLFALLRMGVVPIVNENDTVVTDEIRLGDNDTLGALVTNLIEADSLIILTDQRGLYEADPRKNPDARFISHAQAGDTALEAMAGGAGSGVGTGGMLTKILAAKRAAHSGAHTVIASGRERNVLTRLAQGECIGTELQATLPVWSARKQWMADHLRLRGRLVLDEGAVQALLNEGKSLLPIGVTEVQGDFERGDVVACVDASGRECARGLVNYASADARRIMRHPSSEITQILGSMTAPELMHRDNLVITE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y802_COREF
Sequence: MATGLTPPPQPIKRPPKAVTWIIGIIALLVLVTPLTVGFYTDWLWFGEVDYRGVFSTVIVTRIILFIVFALLAGFVTWLAGYFTIRLRPDDLTAFDAESPVFQYRQMIENSLRRILIIVPIFVGLLGGLVGQRSWQTVQLFLNREPFGVEDQQFGMDYGFYAFTLPMLRLITSSLSTLLVVAFIIALVGHYLLGGIRPGNQMTGQKAFISRGARAQLAVTAGLWMLVRVATYWLERYDLLTRENATFTGAGYTDINAHLPAKIILMVISIIVAVAFFSAIFLRDLRIPGLAVVLLVLSSVVVGAVWPLMLERFSVQPNRAEKESEYISRNIESTRFAYGITDDEVTYIENWGAGGATNAEVAADEATISNIRLLDPQILSPTFTQQQQLRNFYGFPEQLAMDRYEVDGELRDFVVAARELDPNSLQQNQQDWINRHTVYTHGNGFIAAQANQVDEVARDVGSTRGGYPVYTVSDLQTNARAAESEDAEELGIMVEQPRIYYGPLIASAADGKDYAIVGDTGDGPVEYDTDSTSYTYDGEGGVGIGNLFNRAAFALRYQEMNMILSDRVGSESKILFERDPRTRVEKVAPWLTTDSKSYPAVIDGSIKWIVDGYTTLSSLPYATRTSLTEATLDSVVVDNFQQPLLTEEVGYIRNSVKAVVDAYDGTVELYEFDSEDPVLKAWRGVFPDVVQPESEISNELRDHLRYPEDMFKVQREMLSRYHVEDAGTFFTNDAFWSVPNDPTAPEGRQEMKQPPYYVVAADPDTGESSFQLITPFRGLQREFLSAHMTASSDPDNFGKITVRVLPTGAVTQGPKQAQDAMMSSDQVAQDQTLWRGSNDLFNGNLLTLPVGGGEILYVEPIYSQRRDQESAFPKLLRMLVFYKGQVGYAPTIAEALSQVGIDPAAAQDIEVVEEDGTVTVPDVNATEDADATTDGEDETPAAPAAPAGSEAEGIEAINEALRNLEAARDGSFEEYGRALDALDRAVESYQGAGTAE
What are the official names of this protein?
UPF0182 protein CE0802.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIE_ECOL6
Sequence: MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDQRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLSTIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ARGR_KLEP7
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVQALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKDLHDAILVLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.