PharMolix/UniProtQA huggingface dataset:
Protein: NU2C_BRANA
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSFVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSTLVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPSHQWTPDVYQGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIILFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWRAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPHVRNYRISPLRSTNSIELSMIVCVIASTIPGISMNPIIAIAQDSPF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MNMA_BURP1
Sequence: MTKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAQTIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTRVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKTVGKHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAAKDIASNTLYVVQGHDHPWLRSRELVAGNVSWVAGEPPADGARCGAKTRYRQADAPCAFGRAAQAGDERFSLVFDEPQWAVTPGQSAVLYDGDVCLGGGIIESAATGRAGTAPAGRAPALVEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STAA2
Sequence: MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFAS_ECOL5
Sequence: MKLKAIILATGLINCIAFSAQAVDTTITVTGNVLQRTCNVPGNVDVSLGNLYVSDFPNAGSGSPWVNFDLSLTGCQNMNTVRATFSGTADGQTYYANTGNAGGIKIEIQDRDGSNASYHNGMFKTLNVQNNNATFNLKARAVSKGQVTPGNISSVITVTYTYA
What is the function of this protein?
A minor fimbrial subunit, this protein is necessary for full expression of S-specific binding.  S-fimbrial adhesins enable pathogenic E. coli causing urinary-tract infections or newborn meningitis to attach to glycoproteins terminating with alpha-sialic acid-(2-3)-beta-Gal.  This protein binds to the alpha-sialic acid-(2-3)-beta-Gal and is thus responsible for erythrocyte recognition and hemagglutination.
What are the official names of this protein?
S-fimbrial adhesin protein SfaS.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: EFTS_PELPD
Sequence: MAITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGMVAAFVSDDLKSGVLLEINSETDFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGDPSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYIHAGGKIGVMVQVESPAVTSANQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIVGQINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESDFAAEVAAAAGLK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTB_SHIFL
Sequence: MIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFVKMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYILLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPAMGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASRLLNKKVELE
What is the function of this protein?
Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.
What are the official names of this protein?
Spermidine/putrescine transport system permease protein PotB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRG_CAMJD
Sequence: MKQTKYIFVTGGVLSSLGKGIAAASIATLLKNSGLKASILKADPYINVDPGTMSPFEHGEVFVTDDGAETDLDLGHYERFLDESLSQDNNFTTGRVYQSVIEKERRGEYLGKTIQVIPHIVGEIKDRIKKAGEGKDILIVEIGGTVGDIEGLPFLEAIRALRLEVGKNNAMNIHLTLVPFIKAAGELKTKPTQHSVGELRRIGISPDMIICRSEKALDRDLKDKIAISCGVEKNCVIESVDAASIYQIPLNFLKQDILNPIAEILDLKNLKPNMENWDSLVKRVIAPSNEVKIAFVGKYVDLKESYKSLTEAIIHAGAALDTKVELKWVDSEKLENMESAEVFKDVSGILVAGGFGYRGVEGKIKAIQYARENKIPFLGICLGMQLALVEFARNVLKLKDANSSEFDEKCENPVVYLIDEFMDTNGEKQIRTAKTPLGGTMRLGAYKCDIKEKSLLAKVYNEAKSVKERHRHRYEANPKYRVDFEKHGLIVSGESKGLIEAVELNCHPFFLAVQFHPEFTSRLEHVNPVICGFIKAAINYEDN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NUDC_VIBC3
Sequence: MIRLQAIRRSRVEKSDGKNAYWCVVSGSDLWLVDGQIPYGSAEQWDLPQEKAILVDRYQNSPVYWLNAADIEQDRPLTSLRELLGVDEALFLAASKAVQYGHMSQTIRFCPQCGGRNYLNHQQLAMQCHDCRTLHYPRIFPCIIVAVRKQQQILLAQHPRHRNGMYTVIAGFVEVGETLEQCVAREVLEETGIVVTNIRYFGSQPWAFPSSMMMAFLADYDTGELKPDYSELSDANWFGIENLPPVAPRGTIARALIEQTLADIAQDQA
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: Y1931_ENT38
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRGASVFLLLPAGIALALFVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVKLSAYDWAGALVALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein Ent638_1931.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL30_ERWT9
Sequence: MAKTIKITQTRSSIGRLPKHKATLLGLGLRRINHTVEREDTPAVRGMVNAISYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DNLJ_BACAA
Sequence: MSKEIAKKRIEELRDLLNTFNYQYHVLDNPSVSDAEYDRNMQELIKLEAENPEFMSEDSPSIRVGGTVLDIFEKVTHKSPMLSLGNAFNEGDLRDFDRRVRQGIDDANVRYICELKIDGLAVSLHYEKGRFIQGATRGDGVTGEDITQNLKTIKAIPLRLNEEVTLEARGEAYMPKRSFVKLNEEKEQNGEDVFANPRNAAAGSIRQLDPKIAAKRNLSMFVYGLANVEEKTIPSHSESLDYLGELGFKTNPNRRTCETIEEVIAYVEEWQEKRPHLDYEIDGIVIKVDDVALQESLGTTAKSPRWAIAYKFPAEEVVTRLTGIELSVGRTGVVTPTAELEPVRVAGTIVRRASLHNEDLIREKDIRIGDYVVVKKAGDIIPEVVNVIFDKRTGGEEEYHMPTHCPACESELVRLEEEVALRCINPTCPAQIREGLIHFVSRNAMNIDGLGERVITQLFDADYIRTFADLYSLTKEQLLQLERFGEKSATNLVQAIENSKENSLERLLFGLGIRHVGAKAARTFAEHFETMDALVKATEEELKAINEIGEKMAQSVVAYFDNEDVLELLQQFKEYGVNMTYKGIKIADLQNVESYFAGKTVVLTGKLEVMGRSEAKKKIEALGGKVTGSVSKSTDLVVAGEAAGSKLAQAEKHNVEVWNEERFLQELNK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SSRP_SHEB5
Sequence: MVKKNSSKAAPATIARNKRATFEYRFEEKMEAGLSLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPLRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YDIL_ECOLI
Sequence: MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIPDRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQRVYPDGNFIDWKIYQSVAAELYAHDLERLC
What are the official names of this protein?
Uncharacterized protein YdiL.
Protein: LT_POVKI
Sequence: MDKTLSREEAKQLMQLLCLDMSCWGNLPLMRRQYLVKCKEYHPDKGGNEESMKLLNSLYLKLQDSVSSVHDLNEEEDNIWQSSQIPTYGTPDWDEWWSQFNTYWEEELRCNESMPSSPKRSAPEEEPSCSQATPPKKKHAFDASLEFPKELLEFVSHAVFSNKCITCFVVHTTREKGEVLYKKLLQKYQCSFISKHAFYNTVLIFFLTPHKHRVSAINNFCKGHCTVSFLFCKGVNNPYGLYSRMCRQPFNLCEENIPGGLKENEFNPEDLFGEPKEPSLSWNQIANFALEFDIDDVYYLLGSYIRFATKPEECEKCSKNDDATHKRVHVQNHENAVLLQESKSQKNACTQAIDRVIAERRYNCVTLTRKKLLTKRFKKLFNEMDKIVVGERKILLYMASIAWYTGLNKKIDELVVRFLKLIVDNKPKHRYWLFKGPINSGKTTLATALLNLCGGKALNINIPSEKLPFELGVALDQYMVVFEDVKGQIGIEKQLPSGNGVNNLDNLRDYLDGCVEVNLEKKHVNKRSQIFPPGIVTMNEYCIPETVAVRFEKTVMFTIKRNLRESLEKTPQLLSQRILHSGIAMLLLLIWYRPVSDFDEEIQSNVVYWKEVLDNYIGLTEFATMQMNVTNGKNILEKWFE
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PG197_VACCC
Sequence: MDTDTDTDTDTDTDTDTDTDVTNVEDIINEIDREKEEILKNVEIENNKNINKNHPSGYIREALVINTSSNSDSIDKEVIECISHDVGI
What are the official names of this protein?
Protein OPG197.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG197 family.
Protein: DAA10_CHLRE
Sequence: MDLQNKPQILEHLHKSLTVTLYDCRWIPGTAKFVTLGSYARNTGCLQVYELEGPDLKTVKETEKKHSFKCGTFGASSLAERRLATGNFGGEVQIWDLENTAQPVFTAQAHASIVNAIDGCGGQAKGYGAPELATCGRDGCVRVWDVRQQDAPVAAFEPADPNNVRDCWCVAFGNSFNDNERCLLAGYDNGDVKMFDLRMNKVRWETNVRNGVCGLQFDRKDISMNKFAVCCLEAQFHVFDARTQHPKKGFASVSEKITAGATVWGAQHLPQNREVFMVSAGDGNLYLYKYHYPDQRKVKDHDGQELGVAGSVEMLNYKNISTQPVAGFDWSPDKEGLFACVAFDQAVRVGIVTKLNKV
What is the function of this protein?
Key assembly factor specifically required for the stability of axonemal dynein heavy chains in cytoplasm.
What are the official names of this protein?
Dynein axonemal assembly factor 10, WD repeat-containing protein 92.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: RPIA_XANC8
Sequence: MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGTLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHNLHITDPVALERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYS_DESVV
Sequence: MLDLKLLQKNPEVVAKALAMRHSDIDIATFTTLDTRRRALLTEVESLKSERNKASAEVAKAKRAGEDASALIERLGGVSERIKALDLEAEAVKSEQNDWMLTIPNIPHESVPEGRDENDNVEVLRWGTPRAFSFTPREHWDIGVALGGLDFERAGKLAGSRFTVYWKWAARLERALANYFLDTHISANGYTEVLPPFMVNRKTMTGTGQLPKFEEDLFRLESWDYFLIPTAEVPLTNLHADEILEEGDLPLGYTAQTPCFRSEAGSYGKDTRGLIRQHQFTKVEMVRFAHPERSFEELERMRGHAEALLQNLGLPYRVITLCSGDMGFSATKTYDLEVWLPGQDKYREISSCSNCGDFQARRANIRFRPAGGGKPEFVHTLNGSGLAVGRTLVAVLENYQQEDGSVIVPEVLRPYMGGLERITA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_XANOR
Sequence: MSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPEAIAVAEQTFGGDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLEVAGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADVLWTYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALKPGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDAELNVNPRARSAVLRVAEKLELRIGDSLLERRSGRIPNPQSPIPASQGDAR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGOD_ECOHS
Sequence: MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIGGIKTLREIGFDTFKLNGCEELGLIDNSRAVDAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAEAYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFSMVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: PUR7_STRT1
Sequence: MSNQLIYTGKAKDIYSTEDENVIKSVYKDQATMLNGARKETIKGKGVLNNQISSLIFEKLNAAGVATHFIERISDTEQLNKKVTIIPLEVVLRNVTAGSFSKRFGVEEGLDLKTPIVEFYYKNDDLDDPFINDEHVKFLDIANDEQIAYIKEETRRINELLKDWFEQIGLRLIDFKLEFGFDKDGKIILADEFSPDNCRLWDAEGHHMDKDVFRRDLGSLTDVYEVVLEKLQGLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: LEPA_ALTMD
Sequence: MQQSHIRNFSIIAHIDHGKSTLSDRLIQHCGGLTDREMAEQVLDSMDLEKERGITIKAQSVTLNYEARDGETYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDMEVVPVLNKIDLPQAEPDRVAEEIEDIVGIDALDAVRCSAKTGIGIEDVLEVIVNKIPPPEGDREAPLKALIIDSWFDNYQGVVSLVRIVEGQLNKKDKIQIMSNGQTHQVDKIGVFTPKPLDTGILRAGEVGFIIAGIKDIQGAPVGDTITLAREPADAMLPGFKKVKPQVYAGIFPISSDDYEDFRDALAKLSLNDASLFYEPESSAALGFGFRIGFLGMLHMEIIQERLEREYDLGLITTAPTVIYEVETTKGETLTVDSPAKLPPVNDIAEIREPMVEANILVPQEYLGNVITLCVEKRGMQTNMTYHGKQVAVTYELPMAEVVLDFFDRLKSTSRGFASLDYNFKRFQTSDMVRVDILINGERVDALAVITHRENSQGRGRELVEKLRELIPRQMFDIAIQAAIGNHVVARSTVKQLRKNVIAKCYGGDVSRKKKLLQKQKEGKKRMKQVGNVELPQDAFLAVLKVGK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HPPD_COCIM
Sequence: MAPAADSPTLQPAQPSDLNQYRGYDHVHWYVGNAKQAATYYVTRMGFERVAYRGLETGSKAVASHVVRNGNITFILTSPLRSVEQASRFPEDEALLKEIHAHLERHGDGVKDVAFEVDCVESVFSAAVRNGAEVVSDVRTVEDEDGQIKMATIRTYGETTHTLIERSGYRGGFMPGYRMESNVDATSKFLPKVVLERIDHCVGNQDWDEMERVCDYYEKILGFHRFWSVDDKDICTEFSALKSIVMASPNDIVKMPINEPAKGKKQSQIEEYVDFYNGAGVQHIALRTNNIIDAITNLKARGTEFIKVPETYYEDMKIRLKRQGLVLDEDFETLKSLDILIDFDENGYLLQLFTKHLMDRPTVFIEIIQRNNFSGFGAGNFRALFEAIEREQALRGTLI
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4HPPD, HPD, HPPDase, T-cell reactive protein.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
Protein: QUEA_LEGPL
Sequence: MNKQDFYFDLPSELIAQYPLANRSDSRLLIYNRQTEEYGHYQFREIADFLQPGDLLVMNDSKVIPARLYGHKATGGKVELLVERITGDFTFLAHIKASKSLKSNDLIYLDAGKRLEVLQRQDDLFLCKASENILDLLNDLGHIPLPPYIDREDESLDKERYQTVYAKCAGSVAAPTAGLHFDEAVLSSIRARGVNIAYITLHVGAGTFRPVRCERIQDHKMHSEWFTVSPDLCTAVKAAKSMGNRVIAVGTTALRSLESAAMGGELIPCSRDTDIFIYPGYQFKVCDGLITNFHLPESTLVMLVSAFIGHQECMALYQEAIDKRYRFFSYGDASLLL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8687_DICDI
Sequence: MTPYLKIIKSSYTLLSFFYFIANTIIRTIQNVPTSHKIILVSLYYLVFSLFITRIFYGSPLKIISTYIYGKF
What are the official names of this protein?
Putative transmembrane protein DDB_G0272126.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIAB_PSEAB
Sequence: MAKKLFIETHGCQMNEYDSSRMADLLGEHQALEVTENAAEADVILLNTCSIREKAQEKVFSKLGMWRELKQQNPDLVIGVGGCVASQEGAAIRERAPYVDVVFGPQTLHRLPEMIDAARSTRKPQVDVSFPEIEKFDRLPEPRVDGPTAFVSVMEGCSKYCSFCVVPYTRGEEVSRPFDDVIAEVIHLAENGVREVTLLGQNVNGFRGLTHDGRLADFAELLRVVAAVDGIERIRYTTSHPLEFSDALIQAHAEVPELVKFIHLPVQSGSDRVLAAMKRNHTVLEYKSRIRKLKAAVPDICISSDFIVGFPGETEKDFEQTMKLVEDVGFDFSFSFIYSARPGTPAADLADDLPEEVKKQRLQILQSRIHQQGYEISRRMVGSTQRILVTDFSKKDPGMLQGRTENNRIVNFRCDNPRLIGQFAQVHIDDALPHSLRGTLIDSTLH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTR_SHIFL
Sequence: MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFHSNFLTQIERLKPVHVIVFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPEANVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRHQHIDYLV
What is the function of this protein?
May act as a transcriptional regulator of dctA.
What are the official names of this protein?
HTH-type transcriptional regulator DctR.
Protein: FSD1_MOUSE
Sequence: MEDQREALRKIITTLAMKNEETQTFIYSLKQMLLNVEANSAKVQEDLEAEFQSLTSVLEELKESMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQASDSEDFSQAAKEIKDGITMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPTIDLAESLVSDNCVTLVWHMPDEDSKIDHYVLEYRKTNFEGPPRLKEDHPWMVVEGIRQTEHTLTGLKFDMKYMNIRVKACNKAVAGEFSEPVTLETPAFMFRLDGSTSHQNLRVEDLSAEWDAMGGKVQDIKAREKEGKGRTASPVNSPARGTPSPKRMSSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRFEPDSKAFGLGVAYRSLGRFEQLGKTAASWCLHANNWLQASFTAKHANKVKVLDSPVPDCLGVHCDFHQGLLSFYNARTKQLLHTFKAKFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT
What is the function of this protein?
May be involved in microtubule organization and stabilization.
What are the official names of this protein?
Fibronectin type III and SPRY domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle (By similarity).
Protein: PUR7_SALSV
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLVKRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSLGGLIEAYEAVAHRLGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.