PharMolix/UniProtQA huggingface dataset:
Protein: PIMT_PSEPK
Sequence: MTSQRTRERLIQRLCEEGVSNTKVLDVIRRTPRHLFVDEALAHRAYEDTALPIGHNQTISQPFMVAHMSELLLEAGPLDKVLEIGTGSGYQTAILAQLVERVFSVERIKVLQDRAKERLVELNLRNVVFRWGDGCEGWPALAPYNGIIVTAVAPEVPQALLDQLAPGGRMVIPVGPAGEAQQLMLIVREEHGFSRRVLGAVRFVPLLNGPLA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_THAPS
Sequence: MSNIQTGYLNAQDAAALDVELMSTPGFSLEQLMELAGLSVAEAVYEVAFGGDGEKASNDGGRKKRVLLVCGPGNNGGDGLVAARHLAHFGLESTIVYPKQSSKQHFVNLVKQCEDMGIPILQEIPSTNDSSKVEETKYDVIVDAIFGFSFHGTAPREPYATAISQMVQLQKEQSVLLSVDVPSGWDVDGGDLTGTNFHPDVLISLTAPKLSAKKFEGRHFVGGRFLPPSIAEKYGIQKPPYPGVSQVMEL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: CAIC_SALNS
Sequence: MDIVGGQNLRQMWDDLAGVYGDKTALIFESCEGIVRQFSYASINEEINRTANLFYSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFSQLQARQSATLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: THII_VIBVU
Sequence: MKFIVKPHPEIFVKSESVRKRFTKILESNIRIIIQNRTESVAVFNRRDHIEVSANSHQYYQQVLEILTTTPGIQQVLEVKQSGFKDLHDIYEQVLELSRERIENKTFVVRAKRRGKHDFTSIELERYVGGGLNQSVESASVKLHNPDITIKIEVVDDKLNQILAHHKGLGGFPLGTQEDLLSLISGGFDSGVSSYLHIKRGSKVHYCFFNLGGPAHEIGVKQVAHFLWNKYGSSAKVRFISVDFEPVVAEILEKVEDGQMGVVLKRMFMRAAGMVAEKFDIQALVTGEALGQVSSQTLTNLRHIDVVTDRLILRPLINWDKDEIIKVARDIGTEDFAKTMPEYCGVISKKPTVKAVKEKLEAEEANFNFDILEQVVRNARQMDIRDIAKESAQAAPEVEQVQAIEEHAVVLDIRSPDEEDDSPLEIDGVEVKHIPFYKLSTQFGDLDQSKTYLLYCARGVMSRLQALYLQEQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_YEAST
Sequence: MGLLALGTPLQWFESRTYNEHIRDEGIEQLLYIFQAAGKRDNDPLFWGDELEYMVVDFDDKERNSMLDVCHDKILTELNMEDSSLCEANDVSFHPEYGRYMLEATPASPYLNYVGSYVEVNMQKRRAIAEYKLSEYARQDSKNNLHVGSRSVPLTLTVFPRMGCPDFINIKDPWNHKNAASRSLFLPDEVINRHVRFPNLTASIRTRRGEKVCMNVPMYKDIATPETDDSIYDRDWFLPEDKEAKLASKPGFIYMDSMGFGMGCSCLQVTFQAPNINKARYLYDALVNFAPIMLAFSAAAPAFKGWLADQDVRWNVISGAVDDRTPKERGVAPLLPKYNKNGFGGIAKDVQDKVLEIPKSRYSSVDLFLGGSKFFNRTYNDTNVPINEKVLGRLLENDKAPLDYDLAKHFAHLYIRDPVSTFEELLNQDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHRDAILFEKFHWKKSFRNDTDVETEDYSISEIFHNPENGIFPQFVTPILCQKGFVTKDWKELKHSSKHERLYYYLKLISDRASGELPTTAKFFRNFVLQHPDYKHDSKISKSINYDLLSTCDRLTHLDDSKGELTSFLGAEIAEYVKKNKPSIESKC
What is the function of this protein?
Catalyzes the ATP-dependent condensation of cysteine and glutamate to form the dipeptide gamma-glutamylcysteine (gamma-GC), the first and rate-limiting step in the production of glutathione (GSH).
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 3 family.
Protein: RL30_PROMH
Sequence: MAKTIKITQTRSLIGRLPKHKATMAGLGLRRIGHTVEREDTPAVRGMINLVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL18_MYCPA
Sequence: MAQTQADTAARKPVGQSVSATRRVSRLRRHARLRKKIAGTPERPRLVVNRSARHIHVQLVNDENGTTVAAASSIEDDVRSLQGDKKARSVRVGQLIAERAKAAGIDSVVFDRGGYTYGGRIAALADAARENGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PUS7_ARATH
Sequence: MKRKQQEDDNDDGVEKAVSPVLATTSNTMSTDLLLQSSSKLSQKQDYIFHGGRRHVRPYYFEFISHVNKRWTGKTIVDLFADEFKGRPRDYYVGAVKSGRIKVDGEIVPVSYIVKSSQKITHFLHRHEPPVMIDDVVILHQEPDVVTVCKPASVPVHPCGQYRKNTIVGILDAEHDLGTLFPIHRLDRLVSGLLIIARTAAKADFFRQQIEGGMVKKRYIAKVIGVFPEDEMIVDANINYNGSEGRSTAEDANSSGDDKKVKGKPACTKFTRIDTNGTHSLVSCEPVTGRTHQIRVHLQYTGHPIANDPLYLNQHIDNLETYIAKRIDAGERKIVSPDDYVYSSEDFSIDPMCTNCPKLIPQGYEEHDEALWLHCVQYCGTGWEYECPYPSWASL
What are the official names of this protein?
RNA pseudouridine synthase 7, RNA pseudouridylate synthase 7, RNA-uridine isomerase 7.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: METN_RALSO
Sequence: MIELKGISQHFRGAGGTDVHALRDVDLSIDKGEIFGIIGRSGAGKSTLVRVINLLNRPTSGTVTVAGQSLTALNADGLRQARRKIGMIFQHFNLLSSRTVYDNVALPLELAGTPRERIREIVLPLLELVGLDAHKDRYPAQISGGQKQRVGIARALASQPDVLLSDEATSALDPETTRSILDLLRKINRELGLTIVLITHQMEVIKQVCDRVAVLDAGRVVELGRVIDVFLKPRHDVTRALIGEVISQELPPSVLARVESRLVAARERGGRDHLFRLAFTGAGVDQPVLAQAIRNYGLDFNILHGHIDEIQGQAFGSLAILASGESADIDNAMHFLREQGVVVEEINHVV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLN1A_MYCTU
Sequence: MDRQKEFVLRTLEERDIRFVRLWFTDVLGFLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQVLPWATSSGHHHSARMFCDITMPDGSPSWADPRHVLRRQLTKAGELGFSCYVHPEIEFFLLKPGPEDGSVPVPVDNAGYFDQAVHDSALNFRRHAIDALEFMGISVEFSHHEGAPGQQEIDLRFADALSMADNVMTFRYVIKEVALEEGARASFMPKPFGQHPGSAMHTHMSLFEGDVNAFHSADDPLQLSEVGKSFIAGILEHACEISAVTNQWVNSYKRLVQGGEAPTAASWGAANRSALVRVPMYTPHKTSSRRVEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLGPQAEDNVWDLTPEERRAMGYRELPSSLDSALRAMEASELVAEALGEHVFDFFLRNKRTEWANYRSHVTPYELRTYLSL
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYBU_HUMAN
Sequence: MGPLRESKKEHRVQHHDKEISRSRIPRLILRPHMPQQQHKVSPASESPFSEEESREFNPSSSGRSARTVSSNSFCSDDTGCPSSQSVSPVKTPSDAGNSPIGFCPGSDEGFTRKKCTIGMVGEGSIQSSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSHKPGSSPSSPREKDLLSMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSLEEQVTGEGADRELLVGDSIANSTDLFDEIVTATTTESGDLELVHSTPGANVLELLPIVMGQEEGSVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLSPVETPYANVDAEVHANRLMRELDFAACVEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
What is the function of this protein?
Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.
What are the official names of this protein?
Syntabulin, Golgi-localized syntaphilin-related protein, Syntaxin-1-binding protein.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=Colocalizes with syntaxin vesicles along microtubules in neuronal processes. SUBCELLULAR LOCATION: [Isoform 3]: Golgi apparatus membrane; Single- pass membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Golgi apparatus membrane; Single- pass membrane protein. SUBCELLULAR LOCATION: [Isoform 5]: Golgi apparatus membrane; Single- pass membrane protein.
Protein: UVRC_RHOPS
Sequence: MNQDPAETRDTAAPPPADTTSPSPVSPELEPRSAPGAQDIDAASASLTVDEDDEARLPEIDDDSAEVADGPLAVGRAAIEQAVRLAPTSPGVYRMLNAADDVLYVGKAKNVKKRLSSYARPTGHVVRIARMIAATVTVEIISTATETEALLLEANLIKQLRPRFNVLLRDDKSFPYILITGDHWAPQILKHRGAQSRPGRYFGPFASVGAVNRTITALQRAFLVRSCTDSFFESRTRPCLLYQIRRCAGPCTGEVDFPGYTELVREATDFLSGRSRAVKQELAVEMEKASNELEFETAALYRDRLAALSAIQSQQGINPRTVEEADVFAIHQEGGYSCVEVFFFRTGQNWGNRAYFPRAEKSFTPEEVLASFLAQFYDDKPPPKLILLSHDIEECELLANALCIKAGRKVEVAAPKRGEKKELVAHALTNAREALGRKLADTATQTRLMQGLATTLGLPRPPQRIEVYDNSHIQGTNAVGAMIVAGPDGFIKNQYRKFNIRSEGLTPGDDYAMMREVLQRRFKRLAAAKAEGDAAKPKEDDTPLWPDLVIIDGGRGQLNAARGVLTELGLGAEVTLLGVAKGPDRDAGRETLFMPEREAIKLEPRDPVLYFIQRLRDEAHRFVIGSHRKLRKKDIREAGLQEIPGIGPTRKRALLHHFGTLKEIERASIGDLGKVPGISAESARRIFDFFHPGPG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_BACCZ
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRAB_STRP3
Sequence: MIYLAEGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: NADK_FRATN
Sequence: MAFKYHKVAIIGKHYKKEVSQMVETLYAYLQQQGLEIIIENDTAVDTSLVNVAIASLKEIALRCDVAIVVGGDGNFLKASRLLALYSNIPVIGINKGKLGFLTTLAADDNALKNDLYAILKGDSSVTKMSMLKCRVDNNLRAPLEASIALNEIAITASRGLMFGLKVFIDGRYAFDQRGDGLIVSTPTGSTAHAMSAGGPILNPNQNSVVLVPICSHSLNSRPLVISDESVIDIYITDYNDPEPVLSIDGRHDTILKAHQKVTIQKARKKVTVLHTKDYNYYDTLREKLGWSKVLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCTP_HYDVU
Sequence: MYIYNCIFTGKEVFSDAYPHKLEDEGFVWVVDGKYEELADQKFDDSLFGGNKSAEGEDDEGEASTEYKPVVNTLLRAFRLEEPVTITSLNDFKKALKKYTVNLMAKLNESNQSRVAVLKSKLPKYAKQWAEDFDKIRVYVTEGDGFEVEGTLVVITQDVPFGEEKPNDKCKMTVLADSLIKEKF
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_BORDL
Sequence: MFGLIGKKVGMTQVFQSNGIVVPVTVIEFEPNYVIGKKTMERDGYDALIMGSVDLKGSKVSRPIKGQYKKLENIEPKRYVIEFKGLKGYDAGDEVGLDAFREIKYVDITGTTKGKGFQGAMKRHNFSGGPSSHGSKFHRHLGGTGQATTPARTFKGTKMAGRMGGEQQTIQNLEIVFIDEEKRAILVKGAVPGVKGSFVIVKKAKKVGI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: 2NPD_CYBMR
Sequence: MRSQIQSFLKTFEVRYPIIQAPMAGASTLELAATVTRLGGIGSIPMGSLSEKCDAIETQLENFDELVGDSGRIVNLNFFAHKEPRSGRADVNEEWLKKYDKIYGKAGIEFDKKELKLLYPSFRSIVDPQHPTVRLLKNLKPKIVSFHFGLPHEAVIESLQASDIKIFVTVTNLQEFQQAYESKLDGVVLQGWEAGGHRGNFKANDVEDGQLKTLDLVSTIVDYIDSASISNPPFIIAAGGIHDDESIKELLQFNIAAVQLGTVWLPSSQATISPEHLKMFQSPKSDTMMTAAISGRNLRTISTPFLRDLHQSSPLASIPDYPLPYDSFKSLANDAKQSGKGPQYSAFLAGSNYHKSWKDTRSTEEIFSILVQDL
What is the function of this protein?
Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.
What are the official names of this protein?
Nitronate monooxygenase, 2-nitropropane dioxygenase, 2-NPD, Nitroalkane oxidase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: PGCA_STAA8
Sequence: MKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLQSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGFEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
What is the function of this protein?
Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable).  This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i. e.  the predominant glycolipid found in the S. aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Phosphoglucomutase, PGM, Alpha-phosphoglucomutase, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: STP2_PANPA
Sequence: MDTKTHSLPITHTQLHSNSQPQSCTCTHHRQTFSQSCRQSHRGSRSRSSSQSPASHRNPTGAHSSSGHQSQSPNTSPPPKRHKKTMNSHHSPMRPTLHCSCPKNRKNLEGKLKTKKMAKRIQQVYKTKTRSSG
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Nuclear transition protein 2, TP-2, TP2.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity).
Protein: ARGC_CLOK1
Sequence: MVQVGVIGGTGYVGAELIRLLSNHNKIKISGISSTSYEGKSINSLYPGFYDLKELVCEKDDEVIKRSDLIFLALPSGVSEPIVEKAVAKDKICIDMGADFRFKNESSYKKWYGKNFITPKLHESSVYGLPELNREYIKKSRVIGNPGCYATSVQIGVLPLISKGLIEEKGIIADCKSGLTGAGKTLSESSHFVNCNESFSAYKVANHRHTPEIEENLNSVSKEGVKLTFIPHLIPINRGILSTIYTTPKDPIDIEKIHQKYCEFYKEEPFVRILPLGKVSKINNVRLSNYCCISIHYDSENNKLIIISCLDNMIKGAAGQAIQNMNIVLGFDEKEGLTALPAVF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_CERS4
Sequence: MKFTLSWLKDHLETEAPLDEIVTALTDLGHEVEGVEDPVKVLGAFRICRVIEAQPHPNADRLRLCRVATWPNGPDAPSEEVQVVCGAPNARTGLVGVFAPVGTHVPGTGVDLKPGVIRGVESNGMLCSERELMLSDDHDGIIDLPEDAPMGMRFIDYKGVNDPTIEVKITPNRPDGLGVRGLARDLAARGLGRLKPLPVEPVPGLFPSPVSVTIEAALKEKGCPLFAGRTIRGVKNGPSPDWLQARLRSVGLRPISALVDITNYFTIGLNRPLHVFDVAKITGGLRIHAAEGGEELLALDGKTYKLRPGQMLISDDAQPESLAGIMGGELSGCTEETTDVFLESAYWDPITIAATGRALKIVSDARYRFERGVDPAFTLPGLELATRMILDLCGGEASEVVMDGAVPDTSRAYRFDPKRVVSLVGMEIPEAEQRTTLEALGFTLEGELAAPPSWRPDVQGEADLVEEIARVASLTKLQGKPLPRAQAGVPKPILTPLQVREQAARRTLAALGYNECVTYSFIDEAAAKLFGGGSEAVRVENPISSEMTHLRPDLLPGLLRAAARNQARGFADMALCEIGPVFAGGEPGEQQLQATGLLVGASAPRDPFGSRRPVDVYDAKADAEAVLAAVGAPAKMQISRKVPGWWHPGRSGAVGLGPNLLATFGEVHPKILREMDVKGPAVAFTILVANVPLPKVKTPTRPALKLSDLQAVERDFAFVVDASVEALTLVNAAQGADKALIESVRVFDQFSGDKAEAQMGAGKKSLALTVRLQPTDRTLTDKDIEAVSAKIVEKVAKATGATLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHI2_RABIT
Sequence: MERWPWPSGGAWLLVAARALIQLLRADLRLGRPLLAALALLAALDWLCQSLLPPSAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDAMGFTVLATVLEMNGPGALELRACCSPRLKLLQMDLTKPADISRALEFTKAHTTSTGLWGLVNNAGHNDVVADVELSPVATFRNCMEVNFFGALELTKGLLPLLHHSRGRIVTLGSPAGEMPYPCLAAYGTSKAAMALLMDAFSCELLPWGVKVSVIQPGCFKTESVSNVSHWEQRKQLLLANLPGELRQAYGEDYIEHLHREFLHSLRLALPDLSPVVDAITDALLAARPRPRYYPGRGLGLMYFIHYYLPEGLRRRFLQSFFIIPCLPRALRPGQPGATPAPDTAQDNPNPNPDPSLVGAR
What is the function of this protein?
Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as corticosterone, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as 11-dehydrocorticosterone, in the presence of NAD(+) (PubMed:7750480).  Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids (By similarity).  Plays an important role in maintaining glucocorticoids balance during preimplantation and protects the fetus from excessive maternal corticosterone exposure (By similarity).  Catalyzes the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), a major bioactive androgen.  Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone.  Converts 7-beta-25-dihydroxycholesterol to 7-oxo-25-hydroxycholesterol in vitro.  7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).  May protect ovulating oocytes and fertilizing spermatozoa from the adverse effects of cortisol (By similarity).
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, 11beta-OHSD type 2, Corticosteroid 11-beta-dehydrogenase isozyme 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: FMT_CHLTB
Sequence: MSLRVVYLGTPQFAATVLKTLLDAHTHIVGVVTRADKPQKRSSKLISSPVKQLALSKNIPLLQPIKTTDPAFLAQLREWQADVFIVVAYGVILKQELLDIPTYGCYNLHAGLLPAYRGAAPIQRCIMDGGVLSGNTVIRMDAGMDTGDIANVNYVAIGEDMTAGGLAEALAASGGELLLKTLQEIEAGTVRHVPQNEAMATLAPKLTKEEGGIHWDAPASQVYAHIRGVSPAPGAWTRYLSQGKEARRLGVLSARMESFSGNYGDPGEVLGVSGEDLLIACRQGALRLRMVQPEGKASMKAKDFFNGQSRLVSKLF
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.