PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_STRP1
Sequence: MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSYPKTRDLIENGFVETIKAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RL4_BIFLS
Sequence: MANVTLNVTDAKGQATGTVEAPEALFGVSAEDVQAHIPLIHQVVTAQLAAARQGTHATKTRGMVSGGGKKPWKQKGTGRARQGSIRAPQWYHGGTVFGPQPRDYSQRTPKKMKAAALRYALSDRANAGRVAVVEFGITEPSTKAAVAALAPITADKFTTVVFTRDNINEWLSVRNIPTVHPIFVDQLNTYDVITSQYVVFTKEAFEAFVAAKTEPKEA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FIXJ_RHIME
Sequence: MTDYTVHIVDDEEPVRKSLAFMLTMNGFAVKMHQSAEAFLAFAPDVRNGVLVTDLRMPDMSGVELLRNLGDLKINIPSIVITGHGDVPMAVEAMKAGAVDFIEKPFEDTVIIEAIERASEHLVAAEADVDDANDIRARLQTLSERERQVLSAVVAGLPNKSIAYDLDISPRTVEVHRANVMAKMKAKSLPHLVRMALAGGFGPS
What is the function of this protein?
FixJ, when activated by FixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for FixN activation.
What are the official names of this protein?
Transcriptional regulatory protein FixJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_DHBV3
Sequence: MDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWRSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAEALRAVIPPTTTPVPQGYLIQHDEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPERYRGRDAPTIEAITRPIQVAQGGRKTTSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPTPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsid appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsid are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stucked in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions (By similarity).
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus core antigen family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: RL6_LACDA
Sequence: MSRIGLKVINVPESVTVTKNGNEITVKGPKGELTREFDPRIKFEQEDGVIRFSRSNENDKAIHGTMRANLANMIEGVVNGYKKELKLIGVGYRAVAKNNVLTLNVGYSHPVEMKAPEGVTVTTSSATDVTIEGISKQVVGQFAAEIRAVRSPEPYKGKGIRYADEVVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ZFPL1_DROER
Sequence: MGLCKCPKRLVTNQFCFEHRVNVCEHCMVQSHPKCIVQSYLQWLRDSDYISNCTLCGTTLEQGDCVRLVCYHVFHWDCLNARQAALPANTAPRGHQCPACTVEIFPNANLVSPVADALKSFLSQVNWGRNGLGLALLSEEQNSLKAIKPKVASQSAVSNMTKVHHIHSGGERERTKPNGHDAVSPHSVLLMDAFNPPSAGDYASSRRPLLPRQSPIGGTDRDDNKYQRRTPAELFSRWTRRFYAPSSRPPWRRTWFLVTAGILAFVLFVYLMAWLGRGGSDAVDEGWNNPNPQPNHYE
What are the official names of this protein?
Zinc finger protein-like 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFPL1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL2_SHESA
Sequence: MAVIKCKPTSPGRRHVVKVVNSDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRLIDFKRDKDGIPAKIERLEYDPNRTAHIALVLYADGERRYILAAKGMQAGDKIQSGVEAEIKTGNAMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVARDGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MAUN_PARDP
Sequence: MIRWLTLSSRHRAAARRGWLSAHKWWLLRRCCQIAALAAFMSGPLAGYWIMRGNFASSEMLGVLGLSDPYILLQSAFAGWPVAAPALVGALLIGLFYLLVGGRVYCSFVCPVNIVTDTAHWLREKTGLTRDRKLDRRTRLWLLLGTLLAAALTGTIAWEYVNPVSMMQRGLIFGAGLGWSIVLLVFLLDLFVSRRAWCSHLCPVGAFYGLVGRFSLVRVSARNRDACDNCGACFSTCPEPHVIVPALKGEGSPLILSGDCINCGGCIDSCPNRVFAMASRLRP
What is the function of this protein?
Involved in electron transfer.
What are the official names of this protein?
Methylamine utilization ferredoxin-type protein MauN.
Protein: TADBP_CAEEL
Sequence: MADETPKVKTEPAAEVKSPLDEVKEIRKEAELTQTGSDEKKTTDPEFITVQDPNGDEPIELPTVDGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPADGWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPVDLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKRKSDGNSKGFGFVRMSSVGEQNKVLAIPQHMIDGRRCDVKVPDGRSLQDKQGRPSISRIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQSVGPDYGLPAGYRNRRERDRPDRRPIQNEAPLPMPFVRPPQDYSYRQQNSPLERRYWAPGDSRGPGW
What is the function of this protein?
RNA-binding protein which regulates transcription, splicing and RNA-editing (PubMed:25391662).  Limits the accumulation of double-stranded RNA by maintaining the abundance of the mature RNA transcripts that are formed from double-stranded precursor RNAs (PubMed:25391662).  Stress response protein that acts downstream of daf-16 in the insulin/IGF pathway to regulate longevity and the cellular stress response to osmotic, oxidative, proteotoxic and endoplasmic reticulum stress (PubMed:22232551, PubMed:22792076).  Involved in the regulation of physiological processes including aging, fertility, growth and locomotion (PubMed:22232551, PubMed:29760282).  Plays a role in maintaining localization of chromobox protein homolog hpl-2 to gene bodies, perhaps acting via binding to nascent RNA transcripts (PubMed:29760282).
What are the official names of this protein?
Tar DNA-binding protein homolog 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles from the nucleus to the cytoplasm under stress conditions.
Protein: ICK35_TRILK
Sequence: MKTIIVFLSLLVLATKFGDANEGVNQEQMKEVIQNEFREDFLNEMAAMSLLQQLEAIESTLLEKEADRNSRQKRCLGENVPCGDFPCCGKLVCQKTFGYGWLYKSPYCVKPSNG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U17-barytoxin-Tl1a, U17-BATX-Tl1a, Toxin ICK-35.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 03 (ICK-30-40) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: E4PD_PHOPR
Sequence: MTLKVAINGFGRIGRSVLRALYESGKHHHINVVAVNELAEPEAMAHLLQYDSSHGRFFKPVSHDQEHLFIAHENGERDDIRILHQSDITLLPWHDLDVDIVLDCTGVYGSREDGLAHIKAGAKKVLFSHPAANDIDNTIIYGVNHKTLTSEHRIVSNGSCTTNCIVPVIKIIDDAFGIESGTITTIHSAMNDQQVIDGYHSDLRRTRAASQSIIPVDTKLHLGIGRIFPKFVDKFEAISVRVPTINVTAMDLSVTVKTNVKVNDVNQALSEVSRCTLEGIVDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNKHLIKLLVWCDNEWGFANRMLDTALAMHASDAAQHSNKELRSKIAIKNS
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APRIO_BOVIN
Sequence: MEHWGEPIPRTGQSWRQPLSTSGRGWLGSAPWRWLGPASWRWLGPASWRWLGSAPWWWLGTATWWWRLGSRWYPRSMEQTQ
What are the official names of this protein?
Alternative prion protein, AltPrP.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: SP16H_HUMAN
Sequence: MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II).
What are the official names of this protein?
FACT complex subunit SPT16, Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACTp140, Facilitates chromatin transcription complex subunit SPT16, hSPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: OR2LD_HUMAN
Sequence: MEKWNHTSNDFILLGLLPPNQTGIFLLCLIILIFFLASVGNSAMIHLIHVDPRLHTPMYFLLSQLSLMDLMYISTTVPKMAYNFLSGQKGISFLGCGVQSFFFLTMACSEGLLLTSMAYDRYLAICHSLYYPIRMSKMMCVKMIGGSWTLGSINSLAHTVFALHIPYCRSRAIDHFFCDVPAMLLLACTDTWVYEYMVFVSTSLFLLFPFIGITSSCGRVLFAVYHMHSKEGRKKAFTTISTHLTVVIFYYAPFVYTYLRPRNLRSPAEDKILAVFYTILTPMLNPIIYSLRNKEVLGAMRRVFGIFSFLKE
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2L13, Olfactory receptor 2L14.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSN3_XENTR
Sequence: MASALEQFVNSVRQLSSQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSIPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGICVLRQAIDKMQMNANQLTSIHADLCQLSLLAKCFKPALAYLDVDMMDICKENGAYDAKPFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLEAYKKYILVSLILHGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPAELRNLVSKHNETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGAQEAEKYVLYMIEDGEIFASINQKDGMVCFHDNPEKYNNPAMLHNIDQEMLRCIDLDDRLKAMDQEITVNPQFVQKSMGSQDDDSGSKPSSYS
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity).  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 3, Signalosome subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CSN3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL28_RICCK
Sequence: MSRKCDLTGVGVLYGNNVSHSQRKTRRRFEPNLRSVKFKSDITSGAYRLLVNARCISSVEKAGGFDAYILKADDNVLSSAARAIKKKIIQTKTAKSL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DUS_HELPJ
Sequence: MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPLEDHFMAQISGSKESVVKEAVEKINALDHVSGIDFNCGCPAPKVANHGNGSGLLKDLNHLVEILKVIRENTNKKITSVKVRLGFEKKIPKEIAHALNDAPVDYVVVHGRTRSDRYQKDKIDYESIALMKKILKKPVIANGEIDSVKKAFEVLQITQADGLMIGRATLRAPWIFWQIRNNTTELPAVVKKDLVLEHFDKMVEFYGDRGVIMFRKNLHAYAKGEMQASAFRNCVNTLTEIKSMRESIEEFFNQEMLQSEVPLWVELNQKSV
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: EZRA_BACCZ
Sequence: MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVSTTIPKADKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHGHNDMVRQGYVLDYLEVPKEVRDMTKQLQTCLIDIQELHITEAAEKVENLKTRLDGFYDQLEQEVHARHYVEQKTLSVYEDLEEIRTETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILTKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSLEEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIAEYVDNEQTLS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: AMP1_PINHA
Sequence: FSGSVNQACSGFGWK
What are the official names of this protein?
Antimicrobial peptide 1.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: FZD7_HUMAN
Sequence: MRDPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV
What is the function of this protein?
(Microbial infection) Acts as a receptor for C. difficile toxin TcdB in the colonic epithelium.
What are the official names of this protein?
Frizzled-7, Fz-7, hFz7, FzE3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2). Localized in recycling endosomes in other conditions.
Protein: CE034_BOVIN
Sequence: MAAEVQMVLYEDDSVQVQYIDGSRLQLSPCGSEFLFEKAPPVSAHPLQQPERIRQRTHFVISAYREQLQRALDFRNSFATCPFLSESIIPSEMKTRILIDVSEVRWPSLDTGDGMTYMQSGTVRISSLDGHAYLCLPKSQHEFTVHFLCKVSQKPDSSIEVSEKNNKGKKDKQVEKAGKICTRGSLSGQRLKNKENELYHQIMKSEEPSEKSCVNGAKGREVLSSPHPKDTCIYTWVKQCWSVASCPEEWKYPLSLALHFHDKISSMSGIDADITQKRMLTSDVSEERGKEVSVLPRALLLSCPAPHLHRWNFSDSLSQKQFGEEEYSYHELVKVVWYKGVTYRLTHKHMNSIEIYPGDGSVFKSEGAYLGNYFTYYSIREESEEREEKTYAVNNLPPDRPGSPFSVCSLIKQATRILQHCAKMRLSLSHNYRVCCWKMVPGINDSSVLPLLLRESFVPGVGRFLAYSDDKVHAIFLDGITLTLNWNFGSFIEKRQVNRGLTLGWCKLTFPDGQNQLIQIQHPRPYERYVTTVISWCRRLTQISQQEIPIHPSSSVPEESWSVASELEKIQKFNLLLESSGVLNQTSNKKNKQSLDRCKPKSSETLLKEVNEKSVSVALKKTSEILQDIDNLLSNSKW
What are the official names of this protein?
Uncharacterized protein C5orf34 homolog.
Protein: DNLJ_RHOPS
Sequence: MISKSKTAAPDIDKLTKPKAKVELMRLRLAIEGHDKAYYQDDAPKIPDADYDALRRRLEAIEAKFPELLSASSPSQTVGAAPARGFSKVQHAVPMLSLGNAFSDDEVGEFVERVQRFLKLEDIPAIVAEPKIDGLSLSLRYENGTLVRAATRGDGFTGEDVTANVRTIADIPTTLKAKTIPAACELRGEVYMLKHDFLALNKRQEEAGDTVFANPRNSAAGSLRQKDVAITASRPLKFFAYAWGEMSDYPMESPTQHAMLAWLGDAGFTVNPEITLCHSVDDALAFYRRIGEQRAALPYDIDGVVYKVDRLDYQARLGFVSRSPRWAIAHKFAAEQAVTVLEKIDIQVGRTGALTPVARLQPVTVGGVVVQNATLHNEDYIKGVGSDGSPLRDGVDIREGDTVVVQRAGDVIPQIVTVVLDKRPADLPAYKFPHKCPVCGSHAAREEGEAVWRCTGALICPAQAVERLKHFVSRLAFDIDGLGEKQIVLFHERGWVREPADIFTLKARNAELKLEDLEGYGETSVRNLFAAIDARRNIELNRLIFALGIRHVGEGNAKLLARHYGSIDVFLAAMRAAAEGQTPEGNTSEAYQDLDNIAGIGDVVAEAVVEFFAEPRNVGALDALLREIEVLPVEQAKQDTAVAGKTVVFTGALTKFTRDEAKAAAERLGAKVAGSVSKKTDYVVAGEDAGSKLTKARDLGVAVLTEDEWLALIG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PDXT_DESHY
Sequence: MRVGVLAVQGAFIEHEKILQNLGVECLELRNGKDARQDVEGLILPGGESTTQGKLLRELDMFEPLREKIVAGLPVLATCAGLILLAEELANDSARYFATLPVRVKRNAYGRQLGSFYTEEQFGDLGKVPMTFIRAPYIESVGEGVEILAKVKGDIVGVRYKNQIGLSFHPELNGDRRIHQMFLDSISDGKSAPCKQKAV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: CRCB_NEIMF
Sequence: MLSNIIPLSIGAALGATARWLLNLAVPAAMSPATGNLFANWTGALLIGIFAETINHPQWKLLLITGFLGSLTTLSGFSLETVTLLQSNRPASALANIFLHTAGSLLLTWLGLKIGAAVK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_RICTY
Sequence: MTFIEEFIYKGYLHQCTDLDQLTAITQEVKIAAYIGFDCTATSLHIGSLMQIMILRLLQKHGHTPIVIIGGGTSKIGDPSGKEVTRKALTQEDIKRNTAGIKKSLSKFIKFGKDQGDAIILDNAEWLDSLNYLDFLRDFGRHFSVNRMLTMDSVKLRLERSHHLSFLELNYMLLQAYDFYYLSKHYNCILQLGGSDQWGNIVIGADLIRRISGKEVFGMTTPLLTTASGAKMGKTAAGAVWLNEDLLSPYDYYQYWRNCEDADVIRFAKLYSELDIIELNKFEHLVSEDINAAKKQLAYELTKLCHGERLAKLALETAVRIFEQGDIDENLHTFILAPEILQAGISAYKLFYNVNLARSKSEARKIIRGKGAKINDQLVEDENMTIDTNFLLDKKVIKLSVGKKRHILVKV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_AJEDR
Sequence: MKSTQSFSAVAGFVRLPKSSLGQVRYYSILKDMSIPASKQKFIPSSGTYPKGFLVAGAHAGVKESNTRFPDVALICSETPCSAAAVFTANKFQAAPVQVSKQVLETRQGTGIRGVVVNSGCANAVTGKGGLEDAKMMSAKVDECTGTPSADPQNTSTLVMSTGVIGQRLPIKKILDTIPTAHSNLASNHSAWLTAARAICTTDTFPKLLSRTFTLPSSPNRAYHLAGMTKGAGMIHPNMATLLGILCTDVPISPSVLNPLLTHAVSRSFNSISIDGDTSTNDTVALLANGAAGGETITTTSSPDYTAMQTILTNFAQSLAQLVVRDGEGATKFVTVRVRNSPSHADAKVIASTIARSPLVKTALYGKDANWGRILCAIGYSQGIAEGTVVPERTSVSFKPVDGSEELKLLVNGEPEAVDEERAARILQDEDLEIVVDLGGGEKGDKGLGGEEGVYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RSBV_STAAN
Sequence: MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRDIYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVNEGTEVE
What is the function of this protein?
Positive regulator of sigma-B activity.  Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B.  When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).
What are the official names of this protein?
Anti-sigma-B factor antagonist, Anti-anti-sigma-B factor.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: Y3180_DESHY
Sequence: MDYRRLKDLPEELLPRERLFQYGADALSNREILAILLRTGVKGENVLDFSERLLTETGGLSGLARLTVHELTRYRGMGTAKAAELKAALELGRRSVSSDPLVRPVINSPQDIAHLVMEEMRYLDREHFRVVSLSTKNHVLGISSISVGSLNSSLVHPRECFKEAIRRNSNAIILLHNHPSGDPTPSSEDIDVTRRLSDGGQILGIEVLDHVIIGDNRYISLKERGIL
What are the official names of this protein?
UPF0758 protein DSY3180.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: AROE_STRP8
Sequence: MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAFEVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGKGHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNRQATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENLSLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLITGQDMPVDAIKPLLGDK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.