PharMolix/UniProtQA huggingface dataset:
Protein: CA18_CONLE
Sequence: MGMRMMFTMFLLVVLTTTVVSFNSDRESNHENRRTSNQITRGVWDECCKDPQCRQNHMQHCPAR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (Lys-Xaa-Pro instead of the conserved Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Lp1.8, Alpha-conotoxin-like Lp1.7.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1697_CLOAB
Sequence: MDLPSHSINAMKSMEVIDINTGTKLGLIKDLKIDTEEYKVISIILPGSKVGGWFSKGNDIEIDWTDIQKIGVDVILVNGDNLFVNKD
What are the official names of this protein?
Uncharacterized protein CA_C1697.
What is the protein family that this protein belongs to?
Belongs to the YlmC/YmxH family.
Protein: FCTA_ECO24
Sequence: MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.
Protein: SETB2_DANRE
Sequence: METEADTAKTFWSEVDVDGVFDELMEVLRRLRHTLRHNTATDREYVQAMRIVQESKLIRTETEDVLLDEDILTVTVSEPQCSPESLQNGIEPEDPQHSTARLYSDVGVVCSHMSSSRPDPAAPLVFQPHVCSSACVPHLPAHTHHLLGHNPLRAPLLCHFQRVCDDAGVVYKAPCGRSLSCMQEVLHFLLQTQSVCVLQTDRFSFSTQVCVERQVCAAPLLERDLSRGLEPVPVALVNTVDGARPREFRYRRERWPHGCFLSAEPLYSVCCDCTDGCTDAHSCACVRRTAGAAYTHQRLTHTLRTGLFECGPWCGCERSRCENRVVQKGLRVRLQVFRTPEHMWAVRCRDDLDAGTFICIYAGVVLRLQQSSECPAERSGEPAVSDDEVQLVEEWRIPEETHTHTHTLDSSPPLHVPVIQRPAEHSLAQRRDQQQFSISSETEDNRCEQALRKKPRLMESNGLQDSRTHTLTHTHDGVYYLDASREGNVARFFTHSDDPNLFIQNVFTDTHDPQFPLIAFFTCRPVKAGTELTWSCTNTEQQKTEEKHCSV
What is the function of this protein?
Histone methyltransferase involved in left-right axis specification in early development and mitosis.  Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3).  H3K9me3 represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones.  Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats.  Plays a role in chromosome condensation and segregation during mitosis.  During early development, required to specify the left-right axis by repressing expression of FGF8, leading to negatively regulate the dorsal organizer formation.
What are the official names of this protein?
Histone-lysine N-methyltransferase SETDB2, SET domain bifurcated 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YQGF_BURL3
Sequence: MSGASARDATLLAFDYGEKRIGVAVGNALTRSARALVVIQNLNREHRFKAVGDLLAEWRPDALVVGLPMHPDGTPHDMTQQAKRFGNQLNGRFGLPVTWVDERYSSVEAEAGLRERNVRGRARAEMLDAEAARVILQQYLDQLSDHEHH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRP6_ARATH
Sequence: MSERKRELAEEASSTSFSPLKKTKLNDSSDSSPDSHDVIVFAVSSSSVASSAALASDECSVTIGGEESDQSSSISSGCFTSESKEIAKNSSSFGVDLEDHQIETETETSTFITSNFRKETSPVSEGLGETTTEMESSSATKRKQPGVRKTPTAAEIEDLFSELESQDDKKKQFIEKYNFDIVNDEPLEGRYKWDRL
What is the function of this protein?
Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity.  Regulates cell division which is crucial for plant growth, development and morphogenesis.  May inhibit CDK kinases specifically involved in the G1/S phase transition.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 6, Cyclin-dependent kinase inhibitor p22ack1, Inhibitor/interactor of CDK protein 4, KIP-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the CDI family. ICK/KRP subfamily.
Protein: MATK_CALOL
Sequence: MEEFKKYFERDSYWQQHFLYPLLFQEYIYALAHIHNHGLNGSIFYESGEVLGYDNKSSLILVKRLILRMYQQNFLIHSSNESHQNGFVGHKNPFFSQMISGGFAVIVEIPFSLPSLIEKKKKEITKSQNLRSIHSIFPFLVDQFSHLNYVSDILIPYPIHLEILIQIIQSWIQDVPSLHLLRFFLYEYHNWNSFITRKKSLSTFGKENPRFFWFLYNSYVSEYESVFCFLRKHSSYLLSTSYRNLIERTHFYGKIEHLPVVCSNDFHKNLQLFKDPCMHYVRYQGKAILASKGTSLLMKKWKWYLVNFWECNFSFWFQPYRIHINQLSNSSFLFWGYFSIVLINPLPVRSQMLGYSCLIDNTLTKKLETLVPIIPLIGSLSKAKFCNVSGHPASKPIWTDLSDSDIIDRFVRICRTLSHYHSGSSKKQSLYRMKYILRLSCARTLARKHKTTVRAFFQRLGSGFLEEFFTEEQKFLSLVLPRTSLASGSDRVYKERIWYLDIIRINDLVNYSRLAMELCTGNITKRIEKRSKIAFLFSTDMLKCSCSGS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YCF4_NOSS1
Sequence: MTASTTINKGDSPNGDSSASSVLHQKVLGSRRFSNYWWASIVTLGASGFFLAGISSYLRVNLLIVTDPTQLIFVPQGLVMGLYGTAGLLLASYLWLVILWDLGGGYNDFNRETGNIKIFRWGFPGKNRKIEIGSRIQDIQSVRVDIKEGLNPRRALYLRVKGRRDIPLTRVGQPLSLAELETQGAQLARFLGVPLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NRDR_BRUMB
Sequence: MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDSERVERAISGIVRQLESAGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVSETGDNLET
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: VINT_BPPH8
Sequence: MCTHSMITDTKLRKALGKKRDDIEIISDSHGLNARISQAGKISFFYRYRWAGKAVKLNVGDYPAMSITQARERRQQFRNWLTEGLDPREQVKLDKQTRQEAMSVAEAFNYWIERHCIANGLVKVDYYRQVFEKHIAEPMKNVKVDNTAKMHWINVFDSIESRVMAHYMLSLCKRAFRFCVNRSVIASNPLEGLLPSDVGQKPKKRTRRMDDDDLRKIYQWLKSHMSIESVFLVKFIMLTGCRTAEIRLSERSWFRLDDNEWVVPAGSYKTRVHIRRGLSDAAVNLVRNHLKKINTNHLVTSQRKIDGGIKDSPVHSPVASNYARSIWNGTGMAEWSLHDMRRTIATNLSELGCPPHVIEKLLGHQMVGVMAHYNLHDYIDDQKHWLRVWQSHLEEIIGEPFS
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: EI3F2_DROSI
Sequence: MSRNLSMRAKVFLKPLVLFQIIDAYDRRPKGDNQVMGTLLGRNKEDHIEITNCFTVPHKEHSENKRIDLDMTYASEVLELNMFAYPNERVLGWFCTGKSVSRSASLIHDYYVRECGERQPLHLLVDASLKNQRLSTRLYCAVEMGVPGGTKGLMFSLVPLEISSENSDLLAMRCIEKQSQQQASKQMERFAPELVQVVDATRDIQQRLDLLLRYINDVLARKKKPDNVVGRSLQAALTAVPLLDSEKFRLMFNTNLRDMLMAITLSTMIKTQLEISEKLSCMQDQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-2, eIF3f-2, Eukaryotic translation initiation factor 3 subunit 5-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POB3_YEAST
Sequence: MSTDFDRIYLNQSKFSGRFRIADSGLGWKISTSGGSAANQARKPFLLPATELSTVQWSRGCRGYDLKINTKNQGVIQLDGFSQDDYNLIKNDFHRRFNIQVEQREHSLRGWNWGKTDLARNEMVFALNGKPTFEIPYARINNTNLTSKNEVGIEFNIQDEEYQPAGDELVEMRFYIPGVIQTNVDENMTKKEESSNEVVPKKEDGAEGEDVQMAVEEKSMAEAFYEELKEKADIGEVAGDAIVSFQDVFFTTPRGRYDIDIYKNSIRLRGKTYEYKLQHRQIQRIVSLPKADDIHHLLVLAIEPPLRQGQTTYPFLVLQFQKDEETEVQLNLEDEDYEENYKDKLKKQYDAKTHIVLSHVLKGLTDRRVIVPGEYKSKYDQCAVSCSFKANEGYLYPLDNAFFFLTKPTLYIPFSDVSMVNISRAGQTSTSSRTFDLEVVLRSNRGSTTFANISKEEQQLLEQFLKSKNLRVKNEDREVQERLQTALGSDSDEEDINMGSAGEDDESVDEDFQVSSDNDADEVAEEFDSDAALSDAEGGSDEERPSKKPKVE
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  Transcription elongation is promoted by the repression of transcription initiation from cryptic sites.  Also acts in establishing transcription initiation complexes and promotes SPT15/TBP-binding to a TATA box.  Together with replication factor-A protein (RPA), FACT may play a role in nucleosome deposition during DNA replication.
What are the official names of this protein?
FACT complex subunit POB3, Facilitates chromatin transcription complex subunit POB3.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin (PubMed:10413469, PubMed:14585989, PubMed:14739930). Recruited to actively transcribed loci (PubMed:14585989). Associates with the coding region of HTA1 (PubMed:19683497).
Protein: CPNE7_MOUSE
Sequence: MSGDSERAVAPGVVPAPCASKVELRLSCRHLLDRDPLTKSDPSVVLLQQAQGQWLQVDRTEVVKSSLHPVFSKVFTVDYYFEGVQKLRFEVYDTHGPSGLTCQDDDFLGGMECTLGQIVAQKKMTRPLLLRFGRNAGKSTITVIAEDISGNNGYVELSFQARKLDDKDLFSKSDPFLELYRVNDDGSEQLVYRTEVVKNNLNPVWEPFKVSLNSLCSCEETRPLKCLVWDYDSRGKHDFIGDFTTTFAEMQKAFEEEQQAQWDCVNAKYKQKKRNYKNSGVVILADLKLHRVHSFLDYIMGGCQIHCTVAIDFTASNGDPRNSCSLHHINPYQPNEYLRALVAVGEVCQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPKVQLYGPTNVAPIISKVARMAAAEESTGEASQYYILLILTDGVVTDMSDTREAIVRASHLPMSVIIVGVGNADFTDMQILDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHKELPPRSLGAQTGEAAASSAP
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
What are the official names of this protein?
Copine-7, Copine VII.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Translocates to the cell membrane in a calcium-dependent manner.
Protein: SECA_STRE4
Sequence: MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRTGEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAAQNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: LV1A_MESMA
Sequence: MMKFVLFGMIVILFSLMGSIRGDDDPGNYPTNAYGNKYYCTILGENEYCRKICKLHGVTYGYCYNSRCWCEKLEDKDVTIWNAVKNHCTNTILYPNGK
What is the function of this protein?
The edited BmKBTx, similar to beta-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv) (Probable).  Seems to be a rare component in the venom.
What are the official names of this protein?
Lipolysis-activating peptide 1-alpha chain, BmLVP1-alpha, LVP1-alpha.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSDE_CAEEL
Sequence: MERFLRLGGLGGNLGTFGANPQDSNQVDTSETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRTINPQSMALNQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSIPIAYRTHDLEQKMLLNLNKLSWMDAVSVENYSKCGEQNKEHLKAMLKLAKNYKKALEDEKNMTDQELAIKNVGKMDPKRHIADEVSKMLNDNIVQSLAGMMATTSLQ
What is the function of this protein?
Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 14, 26S proteasome regulatory subunit rpn11.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. PSMD14 subfamily.
Protein: INT13_XENTR
Sequence: MKTFSESHKTVFVVDHCPYMSESCRQHVEFDMLTKNRTQGIIPLAPISKSLWTCAIEASMEYCRIMYDIFPFRKLVNFIVSDSGSRTLNSWNQEDQNLQELMAALAVIGPPNPRADPECCSILHGLVEAVESLCKITDYQHESRTELMENADRVANRGRIICITNAKSDSHVQMLEDCVNETIHEHNKLAAGSDHLMQIQKCHLVLIHTYPVGEDSLVSDRPKKELSNVLISEVHSVKAGRHLSTKLNQLVQLHFDLASTTITNIPMKEEQHANTSANYDVELLHHKEAHVEFNKSAGEGYNGSSSRENCLKETVTLKWCTPRTNSVELHYCTGAFRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLMPFAEPRYCMDGGPEVPLERAKEQLERHTRYWPMIISQTTIFNMQAVVPLASVIVKESLSEEDVLNCQKTIYNLVDMERKNDPLPISTAGTRGKGPKRDEQYRIMWNELETLVRAHVRGSDRHQRVMDCLMACRSKPPEEEERKKRGRKREDKEEKAEKPPKENEHEKKWQESERVKSVLDREKEDLAEAEVIKDSPDSPEPPNKKPHIMVEDTGPAEKSKGPMSLLSLWSSRINTANSRKHQEFVGRLNSVNNKAELYQHLKEENGAEGVENGKGSRQ
What is the function of this protein?
Crucial regulator of the mitotic cell cycle and development.  At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling.  At G2/M phase, may be required for proper spindle formation and execution of cytokinesis.  Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (By similarity).  Plays a role in gastrulation and early embryogenesis (By similarity).
What are the official names of this protein?
Integrator complex subunit 13, Cell cycle regulator Mat89Bb homolog, Germ cell tumor 1, Protein asunder homolog, Sarcoma antigen NY-SAR-95.
What is the protein family that this protein belongs to?
Belongs to the asunder family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Protein: SYR_MARMM
Sequence: MPSIADQLSAVLGDAFASLELPRELGRVSPSKQKPEVFPFQCNGAMPAAKQAKTNPRELAAKLIEALHGIPQIGAAEIAGPGFINLRPAEHLYGERAAEIAGDDRAGAPLAAAPRTVMIDFGGPNVAKPMHVGHLRSSVLGDSLQRLFRFRGDTVVSDIHLGDWGLQMGHLITELHEEQPDLVYFDAAITDGYPSEPPVTIEDLARLYPQASVKAKAGPERLEISRSATAELQAGRPGYRALLRHFIDVSVAALKRDFGALGVHFDLWKGESDVDPLIPGLVEDFKARGVAEESEGALIVRVARDGDKKELAPLILVSKTGAALYGTTDLATILDRKQSVDPDLTLYVVDLAQGDHFEQVFRAAEKAGLAEEGALEHVKFGTVNGTDGKRLRTRDGGTFRLADLIASAIERADERLKEAGLAADVSAEEHARVARMVGLAAIKFADLQNYRTTNYVFDLDRFTSFEGKTGPYLLYAAVRVKSLMRRAAEAGVTPGEILVDAQEERDLVLCLDAFGAALDNAADNRAPNALCDHAFTLAQAFSKFYSACPVLVAEDDAVKASRLALAEATLKQLELCLGLLGLEAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3JA_MOUSE
Sequence: MAAAAAAAAAAGDSDSWDADTFSMEDPVRKVAGGGTAGGDRWEGEDEDEDVKDNWDDDDDENKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEESKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNTVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEALVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYEGGYVQDYEDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.  This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site.  It may regulate the interaction between the 43S PIC and mRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J-A, eIF3j-A, Eukaryotic translation initiation factor 3 subunit 1-A, eIF-3-alpha-A, eIF3 p35.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_LARHH
Sequence: MAISTELKAEIVKDYQRAEGDTGSPEVQVALLTARINDLTPHFKANTKDHHSRRGLLKMVSRRRKLLDYLKRTDAEAYRALITRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACP_PSEFS
Sequence: MSTIEERVKKIVAEQLGVKEEEVVNTASFVEDLGADSLDTVELVMALEEEFETEIPDEEAEKITTVQAAIDYVTSHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL51_ORYSJ
Sequence: MAMVGRSLLLLLLLVTLAAGHGVVVVVAFDPNPLQDFCVADPTSKVRVNGLPCKDPAAVTADDFFFSGVGEPAAGGGRGATASRRYGFTARSVDIPGLNTLGASAARVDVAPGGVFPPHYHPRASETAVVLAGAVYFGFVTSYPDSRVVAKVLRRGDVFAVPQGLVHFLHNNGSEPAALYASLSSQNPGLVLVADALLAAPLPVDLVAKTLLTDEATVDKIRANFIVHRS
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 5-1.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: FTHS1_STRPQ
Sequence: MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 1, Formyltetrahydrofolate synthetase 1, FHS 1, FTHFS 1.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: H2A5_WHEAT
Sequence: MAGRKGGDRKKAVTRSVKAGLQFPVGRIGRYLKKGRYAQRVGSGAPVYLAAVLEYLAAEVLELAGNAAKDNKKTRIIPRHLLLAVRNDQELGRLLAGVTIAHGGVIPNINSVLLPKKSPAAAEKEAKSQKAAAKSPKKKTAATKE
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Protein H2A.5, wcH2A-2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.