PharMolix/UniProtQA huggingface dataset:
Protein: KAE1_THESM
Sequence: MIALGIEGTAHTLGIGIVTEDKVLANVFNTLTTEKGGIHPKEAAEHHAKLLRPLLKKALQEAKVNIKDVDVIAFSQGPGLGPALRVVATAARALALRYNKPIVGVNHCIAHVEVTKMFGIKDPVGLYVSGGNTQILALEGGRYRVFGETLDIGIGNAIDTFAREIGLGFPGGPKIEKLAQRGEKYIELPYTVKGMDLSFSGILTEAVRKYKTGKYKLEDIAYSFQETAFAALIEVTERAVAHTGKEEVVLVGGVAANNRLREMLKTMSEERSIKFFVPPYDLCRDNGAMIAYNGLRMFKAGIRFNIEETIVKQKFRTDEMEVTW
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_BUCA5
Sequence: MNINMKDNFKKWLDLQQKKTLLKFLTCGSVDDGKSTLIGRLLHDTKQIYDDQLFFLKSDSKRHGTQGNEIDLALVVDGLQSEREQGITIDVAYRYFSTNKRKFIIADTPGHEQYTRNMATGASTCDLSILLVDARKGLSEQTYRHSFISTLLGIKYLIVAINKMDLVNYKQEIFENIKKDFLIFSKKLANDLNIIFIPMSALLGENIVFKTKLMPWYQGVTLLSFLETIKIKNSISSEELRFPVQYINRPNADFRGYSGILLSGRMHVGQTIKILPENINSRVSRIVTFDKELKKAEIGESITVVLKDEIDINRGDFFVNIDSILQPSQEAIIDIVWMTDNILLAGESYNVKLSGKKIRVYIKEILFKLDVNTLKKVKSHSLVLNSIGRVKIYFSKPVIFDNYSENRMTGNMIFIDLLTNITVGAGMIVNSLDKKGKIPSNKQKDFESDFYDLITRHFPHWNIPKILMKKVYK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: HPRK_CUPTR
Sequence: MELTGVTSQSIFDDNAADLKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLDDETRKRQMGELILLEPPFLVIADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLVVQLVRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADAVSRGQGRLL
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: FBLN3_MOUSE
Sequence: MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
What is the function of this protein?
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways.  May play a role in cell adhesion and migration.  May function as a negative regulator of chondrocyte differentiation.  In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (By similarity).
What are the official names of this protein?
EGF-containing fibulin-like extracellular matrix protein 1, Fibulin-3, FIBL-3.
What is the protein family that this protein belongs to?
Belongs to the fibulin family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=Localizes to the lamina propria underneath the olfactory epithelium.
Protein: Y024_BORAP
Sequence: MSGHSKWSTIKRKKGALDAKRNKIFTKLIREITIAAKIGGGDIESNPRLRVAVSKAKVANMPKDNIEKAIKKGIGGNEGVEYFEITYEAYAPYGVALMIKCLTDNKNRTSSDVKSVLAKGGGSLGTPGSVSYMFYRKGLVVYNLEKYLEDEIMEFALEFGAEDILVSNNEAEVITNPDDFDKVLSLLRTKFKEEMAEIALIPENKISLNKEQAEKIILLIEKLEDFDDVQEVIHNLEIPEELS
What are the official names of this protein?
Probable transcriptional regulatory protein BAPKO_0024/BafPKo_0025.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ALIF1
Sequence: MNKPLPKAIFLMGPTASGKTNLAIELRKRFPVELISVDSALIYKGMDIGTAKPNAEELLQAPHRLIDILDPTESYSAADFRRDALKEMDDIVAQGKIPLLVGGTMLYYKALLEGLSPLPAADADIRAQIEQEAEQFGWEAMHDQLKTIDPVSAERIHPNDPQRLSRALEVFRISGKTLTELTQIKGDALPYEVHQFAIAPKERAEIHRRIELRFANMMEEGFEAEARALYERDDLHADLPSIRCVGYRQMWDYFDGEGTLDEAVFRGICATRQLAKRQITWLRSWKELTWLDSDDIDGALELISTQLEKK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PAC2_SCHPO
Sequence: MQTYTGIIKTPLDAIILFEACRIGLLPRVQRRLSDHERSLIRAGSVFVWDEREAGMRRWTDGKSWSASRVSGSFLTYREMEGKRKPYHHGLSTDGSLKRSPSADTTGNSSLNAYSNEDSGAASLSDEESVDDENLRGLHYKPNGLIKQSFSITTSLNHKLHLISYSSPIPDPSLVTPSSDVNLSRITIPYGLYPDAGPPLVQAPKFLAPYDILVEKVACSEDARVLDKLRQALWL
What is the function of this protein?
Controls the onset of sexual development, by inhibiting the expression of ste11, in a pathway that is independent of the cAMP cascade.
What are the official names of this protein?
cAMP-independent regulatory protein pac2.
What is the protein family that this protein belongs to?
To yeast YEL007w and to the N-terminal of S.pombe gti1.
Protein: YGFZ_ALIFM
Sequence: MMSTLFPTLNLNKDDQLPNFTVSELNDWALITMIGADKKSYLQGQVTCDVVSLAQDEITFGGHCDAKGKLWSIFQLFHHNDGYALFQRKSAIETELTEIKKYAVFSKVDISISDDILLGFTGDKALEWINQHTDSNANVRVSKFGTFAKVSDTQWLLVTTDDKKEELLSLLSEATLCDEAIWSLHHIKHALPQLDDQLCNEHIPQALNLQAINGISFKKGCYTGQETVARAKYRGINKRAMYLLSGISEAQPSAGDAIERSVGENWRKGGTIVSAYRFEDGYTLALAILPNDLDEDTQFKLQESIWEKVELPYTLNDE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMAND_VIBH1
Sequence: MNKNTISNIECVITKPDRHNLITVIVETESGVTGYGCATFQQRPLAVKTMVDEYLKPLLIGKDANNIEDLWQMMMVNAYWRNGPVINNAISGVDMALWDIKAKIANMPLHQLFGGKSRDAIQVYTHATSDTMEGLYEQVDKYLEQGYQHIRCQLGFYGGVPENIQTAQNPTQGSYYDQDQYIENTVEMFKNLREKYGKQFHILHDVHERLFPNQAIQFAKQIEQYNPFFIEDILPPSQTEWLDNIRNQSSVSLALGELFNNPEEWKALIINRRVDFIRCHVSQIGGITPALKLGHFCESFGVRIAWHCPPDMTPIGAAVNTHLNVHLHNAAIQEHVEYKANTQRVFPNAAEPINGYLYASEIAGIGVEMDREAAQDFPVEYRPHEWTQSRLPDGSIHTP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member VME_00770.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: TPIS_ANOFW
Sequence: MRKPIIAGNWKMHKTLKEALQFVEEVKHEVPSNEQVDAVVCAPALFLAHLVEATKGTNVKIGAQNMHFEDQGAFTGEISPVALKDLGVEYVIIGHSERREMFAETDETVNKKVLAAFKHGLVPIVCCGETLEERESNRTNEVVRVQVEKALEGLTEEQVKQVVIAYEPIWAIGTGKSSTAEDANNVCGYIRQVIANKFSQEAANAVRIQYGGSVKPENIAAFLAEEHIDGALVGGASLQPQSFLQLVEAGK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_UREU1
Sequence: MFKISRKNYSDLYGITTGDSVRLGDTNLWVKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNALILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGISTEVSAGEGKIYTAGGLDTHVHWLEPEIVPVALDGGITTVIAGGTGMNDGTKATTVSPGKFWVKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHEDWGATGNAIDLALTVAEKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPASTNPTIPYTVNTIAEHLDMLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVVTRSWQMAHKMKAQFGALKGDSEFNDNNRVKRYVAKYTINPAIAHGIDSYVGSIEVGKLADIVAWEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMRDQFGTYGRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMKWNSATPNLEVDPQTFDAAVDYNDLENWLEQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMD_STRAJ
Sequence: MLKGVENHSLPRTAAFFDLDKTVIAKSSTLTFSKSFYQGGLINRRAVLRTAYAQFVFLAGGADHDQMERMRAYLSALCRGWNVQQVKEIVAETLHDLIDPIIYDEAASLIEEHHTAGRDVVIVSTSGAEVVEPIGELLGADRVVATRMVVGDDGCFTGEVEYYAYGPTKAEAIRELAASEGYDLSRCYAYSDSATDVPMLESVGRPHAVNPDRALRREALARGWPILDFHRPVRLKQRIPGFSVPPRPALVAVAAIGAAAATAGLVWYANRRRANVA
What are the official names of this protein?
Inhibition of morphological differentiation protein.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: MALD1_MOUSE
Sequence: MLPPPPRQPPPQARTARGSLRLQRAFLRGPLGVLRLLQLLAGAAFWITIATSKYQGPVHFALFVSVLFWLLTLGLYFITLLGKQELVPVLGSRWLVVNVAHDLLAAALYGAATGIMIDQTQRHSYCNLKNYRLPCAYHAFLAASVCGGLCLGLYLLSALYGCCRRYQGKEEVV
What is the function of this protein?
Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration.
What are the official names of this protein?
MARVEL domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus. Cytoplasm, cytoskeleton. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization.
Protein: MIAA_RHOCS
Sequence: MPATRPVLLIGGPTAGGKSALALDLAGRLSGTVVNADSMQLYDGLRVLTARPSVAEEARVPHRLYGIVPPSERMSAARWRDLALAEIAAAHDAGRVPVVVGGTGLYLRALAEGLADIPPVPEPVRAEAQALHRALGTPALHARLAAEDPDGAARLHPGDTTRVLRAWEVLRATGRPLGYWQTAGRAAPPPGLRFLTLVCEPPRDRLYAACDARFLRMLEAGALEEVRRLAALGLDPGLPAMKALGVPELLAHLRGDLPLEAATATAQQATRNYAKRQLTWFRHQIAAARRFDPGDCVERNAVMKFCVDNVTQIS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PAXI_PONAB
Sequence: MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQWQPSGSRFIHQQPQSSSPVYGSSAKTSSVSNPQDGVGSPCSRVGEEEHVYSFPNKQKSAESSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSGPPLPGALSPHYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFRIQGLEQRADGERCWAADWPRDGGRSSPGGQDEGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC
What is the function of this protein?
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).  Recruits other proteins such as TRIM15 to focal adhesion.
What are the official names of this protein?
Paxillin.
What is the protein family that this protein belongs to?
Belongs to the paxillin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Note=Colocalizes with integrins at the cell periphery. Colocalizes with PXN to membrane ruffles and the leading edge of migrating cells (By similarity).
Protein: MATRX_MEASI
Sequence: MTEIHDFDKSEWDIKGSIAPIQPTTYSDGRLVPQVRVTDPGLGDRKDECFMYMFLLGVVEDSDPLGPPIGRAFGSLPLGVGRSTAKPEELLKEATELDIVVRRIAGLNEKLVFYNNPPLTLLTPWRKVLTTGSVFNANQVCNAVNLIPLDTPQRFRVVYMSITRLSDNGYYTVPRRMLEFKSVNAVAFKLLVTLRIHKAIGPGKIIDNAEQLPEATFMVHIGNFRRKKSEVYSADYCKMKIEKMGLVFALGGIGGTSLHIRSTGKMNKTLHAQLGFKKTLCYPLMDINEDPNRLLWRSRCKTIRIQAVLQPSVPQEFRIYDDVIINDDQGLFKVL
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: VF63R_ASFB7
Sequence: MPLKRQGRLLGKKKRVLQHILGLNIFKRELIPPCKDPDPYQIQILLKNYILKNVSTVFTYYCQ
What are the official names of this protein?
Uncharacterized protein DP63R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus DP63R family.
Protein: CNO10_CHICK
Sequence: MAADKAADQGAEKHDGAGTSGITDQEKELSSSALQAFLAGNYDACLQHLNTLQDINKDDYKITLNTAVAEFCKSNQTTTDNLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYLLTYQAEKALHLLAVLEKMISQGNNNSKNGKNESGNNTNKDSSNQKAESGALIEVAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSANIAEHPGFMKTGECLRCMFWNNLGCIHFAMGKHNLGIFYFKKALQENDNACAQLGTGSSDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHSNPRLWLRIAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNVVYNDGQSSAIPVASMEFAAICLRNALLLLPEDQQEPKQENGSKPNNQLGGNTENSESSEACSNKSHEGDKFIAAPPSSPLKKQELENLRCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKQTPQCYPSSVTSARTMMLFNLGSAYCLRSEYDKARKCLHQAASLIHPKEIPPEAILLAVYLELQNGNTQLALQIIKRNQLLPSVKTLSDMRKKPVFQPVHSLQPIQMPTFTAVQRK
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the CNOT10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPB_SYNJB
Sequence: MVTATATATNVGYITQVIGPVIDAEFPSGKLPEIYNALKVEGTTESGLKVNVTFEVQQLLGDNRVRAVAMSSTDGLVRGMPVVDTGAPITVPVGQPTLGRIFNVLGEPVDQGEPVQAQEFAPIHRSAPPLVDLTIKPEPFETGIKVIDLLAPFKKGGKVGLFGGAGVGKTVLIQELIHNIAEEHSGLSVFAGVGERTREGNDLYNEMKESGVLDKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGNLQERITSTKQGSITSVQAVYVPADDLTDPAPATTFAHLDSTVVLSRSLAAKGIYPAVDPLDSSSTILQADIVGEEHYNTARAVKQTLQRYKELQDIIAILGLDELSEEDKLVVARARRIERFLSQPFFVAEVFTGSPGKYVKLADTIKGFQRILSGELDNLPEQAFYLVGTIEEAIEKAEKLKSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PRMA_STRMU
Sequence: MDKWQELTITVNREAEEAASNILIECGSQGVVIDDSADYLGKVGKYGEVFPEVEQVEMVTITAYYPESADMTVITAQVNERLAELTDFGLQTGQVQLTTQELAEEDWAENWKKYYEPTRITHDLTIVPSWTDYEVQAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVIDVGTGSGVLSVASSLLGAKEIFAYDLDDVAVRVAQENIDLNVGTENIHVTAGDLLKGIAIEADVIVANILADILVNLTDDAYRLVKDEGYLIMSGIISEKLDMVLEAAHSAGFFLETHMIQGEWNALVFKKTDAISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNS2_DANRE
Sequence: MCVESDGCEIEGCSSSDEVHTLSGSMSPALKSRDLHHCRPGQKFHAALLRCRTPLVAAGILSFGNVLNYMDRYTVAGVLLDIQKQFKVGDSSAGLLQTVFICSFMVAAPIFGYLGDRFNRKIILSCGIFFWSAVTLLSSFITKEYYWLLVLSRCLVGIGESSYSSISPTIIGDLFTNNKRTVMLSVFYLAIPLGSGLGYILGSIAKDAGGHWYWALRVSPMLGLTAGTLILIFVSEPKRGSADQPGGRLKTRTSWVCDMKALAKNRSYVFSSLASAAVSFATGAFGIWIPQYLVRAQVVQKSAESCTYQPCSSRDSLIFGAITCVTGLLGVVIGAVTTRLCRQKTERADPLVCAVSMLGSAIFICLIFVVAKKSIVGAYICIFIGETLLFLNWAITADILMYVVIPTRRATAVAFQGFTSHLLGDAGSPYLIGLISDSLQESYATSEIWQFLSLGYALMLCPFVIVLGGMFFLATALFFLDDRDKAAKQVNQLARPPSTVKVTK
What is the function of this protein?
Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate, which play critical roles in regulating heart development (PubMed:19062281, PubMed:19074308).  Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration (PubMed:19062281, PubMed:19074308).
What are the official names of this protein?
Sphingosine-1-phosphate transporter SPNS2, Protein spinster homolog 2, Protein two of hearts.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Protein: TATB_ECOL5
Sequence: MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNETAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKTAAPSPSSSDKP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IOLB_LACCA
Sequence: MSLLYHKQNQELSSGVRLIQDVNASNSPMKYTAVKVLEFSADSSYEETLEAFEAGIVVLEGKVTITADDQTFEDVGQRTSIFDKIPTDSVYVSTGLAFGIRAKQAAKILIAYAPTNQTFPVRLIRGNIHQVEHRGKYNNKRLVQNILPDNLPFADKLLLVEVYTDSANWSSYPPHRHDHDDLPAESLLEEIYYHEMRPKQGFVFQRVYTDDLSLDETMAVQNQDVVVVPKGYHPVGVPDGYDSYYLNVMAGPTRVWHFHNAPEHAWIIDRQ
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.
Protein: RRF_LEPBJ
Sequence: MASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISVPEPRMLVISPYDKGIMKDIEKAIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKSKSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQKTTDSYIDKISALTAEKEKEITTI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD1_DANRE
Sequence: MCGSSMASEKQVKFVIVGGGIAGVTCAEQIASQFPSDEVCLLTASPLVKKVTNFRQVSKTLEEFDIEEQPSRVLEEKYPNLKVLQSAVRLLKAREHLLETEDGQRFFYRKLCLCSGGRPKLLSKDNPHVLGIRDTDSAQEFQKRLSTAKRIVVIGNGGIALELVYEVEGCEVIWAVKDKAIGNTFFDAGAAQFLIPSLEADRREASSVCKRARYTTDSSAAGHSGSSSELGSALGPDWHEGIELRGAKQSVRGVHIEYECEVEQIYTQQELLQSEHGTKTAELGVWPAYVQLTNGKIYGCDFIVSATGVVPNTDPFLPGNNFDVAADLGLLVDDHMRTSEADVFAAGDVCSAGWEPSSIWQQMRLWTQARQMGWYAARCMAADVLDEPIELDFCFELFSHITKFFNYKVVLLGKFNAQGLGQDHELLVRCTKGQEYVKVVLSGGRMVGAVLIGETDLEETFENLILNQMDLTRYGEELLNPNIDIEDYFD
What is the function of this protein?
Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response (By similarity).  Required for normal sarcomere structure and muscle fiber integrity (PubMed:27745833).
What are the official names of this protein?
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, myofibril, sarcomere.
Protein: RL34_PSEPK
Sequence: MKRTFQPSTIKRARTHGFRARMATKNGRAVLSRRRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PYRK_GEOTN
Sequence: MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQIDHKQGQCIIIYRQEGKGTALLTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGVPPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGETYIATDDGSYGMAGRVTDVIEQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAYKKVCSDGPVFRAGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.