PharMolix/UniProtQA huggingface dataset:
Protein: SYWM_DICDI
Sequence: MKIDEVNFKDKTKVTVFSGMQPTSSALHLGNYLGAMGNWLKIQDLVTKNNKEEEELLNLSESSSSSSSSQSTKINEKHKLIFSIVDLHSLTSTKSLSPKELQSNTISVAINYLACGIDPEKVILFNQSMVPAHSELTWILNCITSFSKLSNMIQFKEKTKSSNEASVSNGLLSYPVLMAADILLYKATHVPVGEDQTQHLEFTRDIAQAFHSNFKSKFFPYPSIITSEQSKRIMSLQDGRLKMSKSDPLEISRISLTDTDDQIKLKIKKSKTDTIIGITYDPINRPDISNLLSIASETSGIPITDLQSEFKDKSNAIFKEFLSNSIIKNISPIREKINYYQSNPKLVRDILLQGSEKANKIANKNLNIIKDIVGLYH
What are the official names of this protein?
Tryptophan--tRNA ligase, mitochondrial, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYP_HAEI8
Sequence: MRTSQYLFSTLKETPNDAQVVSHQLMLRAGMIRPMASGLYNWLPTGIRVLKKVEKVVREEMNKGGAIEVLMPVVQPAELWEESGRWDQYGPELLRFEDRGNRNFVLGPTHEEVITDLVRREVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFIMKDAYSFHTTQESLQATYDVMYQVYSNIFRRLGLDFRAVQADTGSIGGSASHEFQVLASSGEDDVVFSTESDFAANIELAEAIAIGERQAPTAEMCLVDTPNAKTIAELVEQFNLPIEKTVKTLIVKGADENQPLVALIIRGDHELNEIKAQKHPLVADPLEFADETEIKAKIGAGVGSLGAVNLNIPAIIDRTVALMSDFSCGANIDGKHYFNVNWVRDVAMPEVFDLRNVVEGDPSPDGKGTLQIKRGIEVGHIFQLGKKYSEAMKATVQGEDGKPLVMTMGCYGIGVTRVVASAIEQHHDDRGIIWPSDEIAPFTVAIVPMNMHKSEAVQKYAEELYRTLQSQGVDVIFDDRKERPGVMFADMELIGIPHMVVIGEKNLDNGEIEYKNRRTGEKEMISKDKLLSVLNEKLGNL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBG_DUGDU
Sequence: MVYFTAEEKAAITSLWGKVNVEEAGGKALGRLLIVYPWTQRFFDKFGNLSSASAIMGNPKIKAHGKKVLNSFGDAVENPDNLKGTFAKLSELHCDKLLVDPEDFRLLGNVIVIVLANHFGKEFTPQVQAAWQKMVTGVASALARKYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CKS1_MOUSE
Sequence: MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK
What is the function of this protein?
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
What are the official names of this protein?
Cyclin-dependent kinases regulatory subunit 1, CKS-1, Sid 1334.
What is the protein family that this protein belongs to?
Belongs to the CKS family.
Protein: PLCB2_RAT
Sequence: MSLLNPVLLPPKVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTHQSKEMEFLDVTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTFTVVSGPDMVGLTFHNFVSYKENVGKDWAEDVLALAKHPMTANASRSTFLDKILVKLKMQLSPEGKIPVKNFFQMFPADRKRVEAALSACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQALIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLAHDTLRIHQDMTQPLNHYFINSSHNTYLTAGQFSGPSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAVEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRTMFGETLLTEPLENFPLKPGMPLPSPEDLRGKILIKNKKNQFSGPASPNKKPDGVSEGGFPSSVPVEEDTGWTAEDRTEVEEGEEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYLVSSFTELKAYELLSKASMQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRQDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPTANSINPVWKEEPFIFEKILVPELASLRIAVMEEGGKFIGHRIIPINALHSGYHHLCLRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKYFSAHDKKSVKLKEVTGSLPEKLFSGIPVASQSNGAPVSAGNGSTAPGTKAKEEATKEVAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQDPAASCKLRPGKGSRKKRIVPCEETIVVPREVLEGPDPRVQDLKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREKQAAELKSFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEEKQTACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESMRACFKACFPTEAEEKPERPCEASEESCPQEPLVNKTDTQESRL
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  This protein may be involved in the transduction of bitter taste stimuli.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2.
Protein: DPOG1_DROME
Sequence: MQFHLIRKYASKVSREHYASSSVKIFRRVKPPQKVNKPKKPENVENGPTEYAENLVKVQMISRNLHAQLFPQAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLSVEKLEPLDVDTDSERPHYTTDELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQRAMLKSKKEPAAEDLGWLEQSSLNSLVEVHRLYCGGDTLSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSNWERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQNLWLWDEDWSVQELKLKQPPKRKPLPTVELKDSGNTPEERRLQAKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVPFRSDSEGVDRLPMEQLLAHCPVPEFARLSASKAESDMAFDMLPGQVEQHLGKREHYKKLSQKQQRLETQYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVVWLDSQQLPNEFTGEKCQPIAYGAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLREEFHDELEDRAYSSYEASRLAIQRNRTLAEVFHRPNWQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGSHVRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGGNDVSQWDWIKKS
What is the function of this protein?
As the catalytic component of the DNA polymerase gamma complex is involved in the replication of mitochondrial DNA (mtDNA) (PubMed:3095323, PubMed:7499423, PubMed:8798543, PubMed:11917141, PubMed:19924234, PubMed:15537632, PubMed:28430993).  Has both 5'-3' DNA polymerase and a highly mispair-specific 3'-5' exonuclease activity (PubMed:2671990, PubMed:7499423, PubMed:8798543, PubMed:28430993, PubMed:26554610, PubMed:15537632).  At the end of mtDNA replication DNA ends are ligated to produce a closed circular mtDNA molecule, its exonuclease activity is required for formation of these ligatable ends by preventing DNA synthesis from continuing past the 5'-end of downstream DNA into duplex DNA regions (PubMed:28430993).  Does not possess DNA primase activity, does not catalyze strand displacement synthesis and does not contain a 5'-3' exonuclease activity to catalyze nick translation (PubMed:3095323).  Important for promoting the elimination of paternal mitochondrial DNA during spermatogenesis, however its exact role in this function has not yet been identified and appears to be independent of its 3'-5'-exonuclease activity and only partially dependent on its DNA polymerase activity (PubMed:28318978).
What are the official names of this protein?
DNA polymerase subunit gamma-1, mitochondrial, 3'-5' exodeoxyribonuclease, DNA polymerase gamma subunit 1, Mitochondrial DNA polymerase catalytic subunit, Protein tamas.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Mitochondrion. Note=In sperm, detected in puncta that associate with mitochondrial nucleoids at developmental stages when the nucleoids are being eliminated.
Protein: Y041_NPVOP
Sequence: METLAISDKEQFQTRLAYVADIAAMMQRTLQFMAVHGACTRADAATLCLADDTAAWVCGRGAAPAFASFRVRIAGFQHPCRALAHFMFEESLAQRCSKPLPRYTYMNYAFFRGVLAIKLSVYVGDLHADGLPYFVDFARGRALVRTRAPLQFPLPPFERRVEEAVAQSAAK
What are the official names of this protein?
Uncharacterized 19.0 kDa protein.
Protein: MURE_HAEDU
Sequence: MKRLLPFLTDLEAWVEQLIPLKQMTLDSRQVTEGDLFIALKGHQCDGRQFIQNAIEQGAAIILAEAESDQDEIELDSQFARYNLDRRACKVITVPRLAERLSAIADSFYASPSAKLKLIGITGTNGKTTTAQLLAQWHNLLGGHSAVMGTIGNGLYGQEQEAINTTGSAIEVQQNLARFVEQGADFCAMEVSSHGLAQYRVEALQYDLAIFTNLSRDHLDYHHSIAAYEAAKFRLFNALQTKAQVLNADDQVAQNWLSMLPNAVLVSCDPNFTSEHQFVKATKVNFSLQGAYIEFESSWGNGQFHSQLSGAFNVTNILLALAGLLTLGYDLAKLVATASQLRSVTGRMQKVSAITDKNRPLVLVDYAHTPDALQKALQAARLHTKGKLFCVFGCGGDRDCGKRPLMATIAEELADGVIVTNDNPRTEDQHKIVAEIMQGFAKPDNILVIYDREQAIQHAIKHASSADLILIAGKGHENYQIIGTIKHHFSDQEIASKYLSQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPL11_CAEEL
Sequence: MPFGNDPPDYVHLRSNESQMQLITISENSDIPTPSGSPCFNAPARDEAPSVIFIPGKKFQGTFRWWKSRTTMEKLLLPVLLLFCLLTAVLLAVIINTDKRIEAMKTDHATQTEHAGFGDPTENPTKTAEDPRVPPIVPEAPTSPEPEVTTSTEKPKEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVTESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW
What is the function of this protein?
Probable cell surface protease.
What are the official names of this protein?
Neprilysin-11.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: TX11_ANDCR
Sequence: MMKLVLFSIIVILFSLIGSIHGADVPGNYPLDSSGNKYPCTVLGDNQSCIDVCKKHGVKYGYCYSFKCWCEFLEDKNVSI
What is the function of this protein?
Probable neurotoxin that inhibits ion channels (By similarity).  Is toxic to mice.  Is about 2. 8% of the total protein in the venom.
What are the official names of this protein?
Toxin Acra1, Acra I-1.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium/Potassium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: XGEA_ASPTN
Sequence: MKLSVLSLASLASAAALNAKVLTGKSLTRRADFCDQWGQVTTGNFILYNNLWGQGNADSGSQCTGLDSSSGNDSIAWHTSWSWSGGAGQVKSYANAAYVFTPKQLSALGSIPTSWSWKYTGSDIIANVAYDLFTSSTADGDNEYEIMIWLAALGGAGPISSTGSPVASPTVAGHSWDLYSGMNGQMQVYSFVASSQTESFSADLQEFIMYLQSNQGLPTSQYLVDVQAGTEPFSGSDATLTTSAYSVSVA
What is the function of this protein?
Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues.  Specific for xyloglucan and does not hydrolyze other cell wall components (By similarity).
What are the official names of this protein?
Probable xyloglucan-specific endo-beta-1,4-glucanase A, Xyloglucanase A, Xyloglucanendohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 12 (cellulase H) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RTPT_YEAST
Sequence: MGKGAAKYGFKSGVFPTTRSILKSPTTKQTDIINKVKSPKPKGVLGIGYAKGVKHPKGSHRLSPKVNFIDVDNLIAKTVAEPQSIKSSNGSAQKVRLQKAELRRKFLIEAFRKEEARLLHKHEYLQKRTKELEKAKELELEKLNKEKSSDLTIMTLDKMMSQPLLRNRSPEESELLKLKRNYNRSLLNFQAHKKKLNELLNLYHVANEFIVTESQLLKKIDKVFNDETEEFTDAYDVTSNFTQFGNRKLLLSGNTTLQTQINNAIMGSLSNEKFFDISLVDSYLNKDLKNISNKIDSKLNPTSNGAGNNGNNNNTTNL
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein PET123, mitochondrial, Mitochondrial small ribosomal subunit protein mS26.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS26 family.
Protein: FFSI_ASPFV
Sequence: MAEAITSVPAKSSLSAFWWASKHPPADPTTSFAGKTILITGPNAGLGYEAALKFAALGASQLIFGVRSLARGKEAKASIEAKTKCAPSVIHLLQLDMASYASIESFAREVNSKFPVVHAAVLNAGVAPPAYKRSPEGWEMALQVNVISTAYLAILLLPKLRATGIAAGEPTHLEFVTSVGHGDVAVETVRDARSILGKVNEEANFKFTAQYSITKLLEMWVMRHVAAAARSSEVIVNGACPSLCKSSLGRDFSIMLRAPDSLMKAIIGRTAEQGSRILVSAVTTGQKAHGGFWSHDRIAVPGVLVTSDEGKKLSEQFWKEILDELSKQNPDVEKLLSESS
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the cytotoxic leucine-containing cytochalasans, including aspochalasin C, aspochalasin E, TMC-169, flavichalasine F, aspergillin PZ, aspochalasin M and flavichalasine G (PubMed:32913332).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS ffsA that utilizes 8 units of malonyl-CoA to iteratively assemble the octaketide chain before addition of L-leucine by the C-terminal NRPS modules (PubMed:32913332).  Because ffsA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase fssC (Probable).  The methyltransferase (MT) domain of ffsA catalyzes the alpha-methylation at C10 and C14 using S-adenosyl-L-methionine as the methyl-donating cosubstrate (Probable).  Reduction by the hydrolyase ffsE, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ffsF then yield the required isoindolone-fused macrocycle (By similarity).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase ffsD, the FAD-linked oxidoreductase ffsJ and the short-chain dehydrogenase/reductase ffsI, are further required to afford the final products (Probable).
What are the official names of this protein?
Short-chain dehydrogenase/reductase ffsI, Cytochalasans biosynthesis cluster protein ffsI.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TRHO_CORU7
Sequence: MAVSATDLKESRILLYYCFTPIADPTAIMLWQKQLCESLGLTGRILISEHGINGTVGGSLHACKQYARRTREYPGFKGMEFKWSQGGAEDFPRLSVKVRDEIVSFGAPGELKVDENGVIGGGTHLKPEEVNKLVEERGDDVVFFDGRNAMEAEIGRFKNAVVPDVETTHDFIKELESGKYDWMKDKPVVSYCTGGIRCEVLSALMKNRGFEEVYQIDGGIVRYGEKYGDKGLWEGSLYVFDKRMHMEFSEEAKQLGFCKNCGAATNTFHNCENSECREQILLCEDCAADPAVTCGEC
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ACCD_NOSP7
Sequence: MANNEESRGLKSLFDWFANRRKSGSTSLERQEREIADGLWHKCSKCGVLAYTKDLKANQMVCIECGHHNRVDSDERIRQLIDNNTWKPLDEHLRPTDPLEFRDRKLYSDRLRETQDKIGLIDAVRTGLGQINGLPIALGVMDFRFMGGSMGSVVGEKLTRMIEQATQRRYPVVIICTSGGARMQEGMLSLMQMAKISAALQRHKDARLLYIPVLTNPTTGGVTASFAMLGDIILAEPKATIGFAGRRVIEQTLREKLPENFQTAEDLLQHGFVDDIVPRTQLKNTLAQLIALHQPVLTPPHMVLWETMSLTSTAAE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_CALS8
Sequence: MKLNVCYLEMVEYEDALHLQERLHKLRVANELEDTLLLLQHPPVITIGRRGKWENILISKEKLLQMGVKVFEVTRGGDVTYHGPGQIVGYPIFDLGTVGKDIKRFVWLLEEVFINLLKDEYGIEAYRDEKQYTGVWVGGEKIVAIGIAVKKWITMHGFAFNVNTNLEHFSWIIPCGLKDRGVTSLEKLLGHKVEFDDVVYKVAKYFGKVFGAKFRFISKEDLEEIIKIKVEDSER
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMS_MOUSE
Sequence: MKHPLPHYSPILFIYCFCMLQIPSSGASPPLADSPDGLDIVDPERLAYFLKQREIHSNQPKENQDVYKRFLFHYSRTRKPTHPVSAEFAPVHPLMRLAAKLASRRMKRLPRLLRLDSRMATVDFPKKDPTTSLGRPFFLFRPRNGRYTDNNFQ
What is the function of this protein?
Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.
What are the official names of this protein?
Neuromedin-S.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_ERYLH
Sequence: MTAFKQGDPTTLNRLYGRSIGKPLRTHQQHLVDNLLPQISPPAEGPVTAERLFGEDCPLHFEIGFGGGEHLVYRADLLPNHGFIGAEPFLNGVASCLSQVEEQRLANIRIHNGDALEVLDRVPDGALTMLYLLHPDPWPKNKHAKRRMMNDGPVKMFADKLKPGGEFRFGTDHPVYLRHALMVMRRHTDAFEWVVEGPSDWQNRPSGWPETRYEHKARTKFGHEVWYFRFRRR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SC23A_CHICK
Sequence: MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLRERPDLPPVQYEPVLCSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYAGISEVNQPAELMPQFSTIEYIVQRGPQTPLIFLYVVDTCLEEEDLQALKESLQMSLSLLPADALVGLITFGRMIQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLSRPAVPIQQGRPLQAPEQPVISSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYETLANRTATNGHCIDIYACALDQTGLLEMKCCANLTGGHMVMGDSFNTSLFKQTFQRVFNKGLNGEFRMAFGANLEVKTSRELKIAGAIGPCVSLNVKGPCVSENELGIGGTSQWKICGLDPCTTLAIYFEVVNQHNAPIPQGGRGAVQFVTQYQHSSTQKRIRVTTIARNWADAQSQLQHIEAAFDQEAAAVLMARLGVYRAESEEGPDVLRWLDRQLIRLCQKFGQYNKDDPNSFRLSESFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYAYSFHGPPEPVLLDSSSILPDRILLMDTFFQIVIYLGETIAQWQKAGYQDMPEYENFKHLLQAPLDDAQEILQTRFPMPRYVHTEHGGSQARFLLSKVNPSQTHNNLYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.
What are the official names of this protein?
Protein transport protein Sec23A, SEC23-related protein A.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Note=Enriched at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).
Protein: ERA_LISMO
Sequence: MSEPFKSGFVAIVGRPNVGKSTLLNHIIGQKIAIMSDKAQTTRNKVQGVYTTDESQIIFIDTPGIHKPKHKLGDFMVKIALNTFQEVDLIYFVIDASTGFGRGDEFIIEKLKNVQTPVFLLINKIDLIAPEDLFKLIEQYRDLMDFDEIIPISALQGNNVPNLLEQTNANLEIGPMYYPKDQITDHPERFIISELIREQVLQLTREEVPHSVAVVIEGIEKNPKTEKLTINATIIVERSTQKGIIIGKQGQMLKQIGMRARKEIERLLGSKVFLEIWVKVQKNWRDKEHYLQDYGFDREEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: GRK4_MOUSE
Sequence: MELENFVANNLLLKARLGFNKQTGRSKKWRELLKFPPVSMCTELRWSIEKDFSSLCDKQPIGRLLFRQFCDTKPDLKRCIEFLDAVAEYEVTIEEEQREFGLAIFSRFFKEKSEVPLPEIPPDIVKECKWNLKQNSPSQNVFEECAGIVCKYLSETPFEEYQESTYFNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLEDLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEMVRGRVGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEYSERFSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDPQAIYCRNILDIGQFSVVKGVNLDTNDEIFYAEFATGSVTIPWQNEMIESGCFKDLNENEDDLSSLEKYKMCSSILRPKRNFFRRLFRRTGCLNIALSEEREPTEH
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors.
What are the official names of this protein?
G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex.
Protein: NPR3_ARATH
Sequence: MATLTEPSSSLSFTSSHFSYGSIGSNHFSSSSASNPEVVSLTKLSSNLEQLLSNSDCDYSDAEIIVDGVPVGVHRCILAARSKFFQDLFKKEKKISKTEKPKYQLREMLPYGAVAHEAFLYFLSYIYTGRLKPFPLEVSTCVDPVCSHDCCRPAIDFVVQLMYASSVLQVPELVSSFQRRLCNFVEKTLVENVLPILMVAFNCKLTQLLDQCIERVARSDLYRFCIEKEVPPEVAEKIKQLRLISPQDEETSPKISEKLLERIGKILKALDSDDVELVKLLLTESDITLDQANGLHYSVVYSDPKVVAEILALDMGDVNYRNSRGYTVLHFAAMRREPSIIISLIDKGANASEFTSDGRSAVNILRRLTNPKDYHTKTAKGRESSKARLCIDILEREIRKNPMVLDTPMCSISMPEDLQMRLLYLEKRVGLAQLFFPTEAKVAMDIGNVEGTSEFTGLSPPSSGLTGNLSQVDLNETPHMQTQRLLTRMVALMKTVETGRRFFPYGSEVLDKYMAEYIDDDILDDFHFEKGSTHERRLKRMRYRELKDDVQKAYSKDKESKIARSCLSASSSPSSSSIRDDLHNTT
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Involved in the regulation of basal defense responses against pathogens.
What are the official names of this protein?
Regulatory protein NPR3, BTB/POZ domain-containing protein NPR3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_PECCP
Sequence: MSSIKLIVGLANPGAEYAATRHNAGAWFVDRLADAYRQPLKEESKFFGYTSRLNLAGQDVRLLVPTTFMNLSGKAVAAMATFYRIQPDEILVAHDELDLLPGIAKLKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKSKVTGFVLGKPPTSEQTLIDDAIDEAVRCTEILMKEDMIKAMNRLHAFKPA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.