PharMolix/UniProtQA huggingface dataset:
Protein: ECPT2_ASPRC
Sequence: MQPYHTLSRVLPFPDANQKAWWDKLGPMLLKAMQSQGYDTEAQYAQLGMVYKCVLPYLGEFPTVENDATRWKSFLCPYGIPIEPSLNISQGILRYAFEPIGPDVGTEKDPQNMNIIQDCLKGLTQHDDRIDTTLHAEFSSRLLLTEEESRQFATTGQFNFGPGQGMHGFAVDLKGSRPMFKGYFCAGIKSVVTGIPTGKLMLDAVREVDTEGRITQPLDKLEEYSANGIGKLMLCFMSVDMVNPHDARIKMYGLQQEVSREGIVDLWTLGGRVNTPTNQEGLELLLELWDLLQIPAGPRSVAISHCSVGQPPEYMLPTLVNWTLLPGHSDPMPQVYLVPFGLPDSHISDCLVTFFERRGWTDLARDYKKNLASYFPDIDFTQSRHVQEAISFSFRKGKPYLSIYMSLF
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of echinulin family alkaloid (PubMed:29072465, PubMed:33381959).  The pathway begins with the biosynthesis of the cyclic dipeptide cyclo-L-Trp-L-Ala (cyclo-TA) by the NRPS echPS via condensation of L-alanine and L-tryptophan (By similarity).  The prenyltransferase echPT1 then catalyzes the first prenylation step, a reverse prenylation reaction at C2, to yield preechinulin (PubMed:29072465, PubMed:33381959).  Preechinulin is the substrate of the cytochrome P450 monooxygenase echP450 that catalyzes the formation of the double bond between C10 and C11 to produce neoechulin A (PubMed:33381959).  The unique prenyltransferase echPT2 functions as a competitive enzyme with echP450 for preechinulin metabolization and uses preechinulin for effective regiospecific prenylations.  Preechinulin is prenylated by echPT2 at C5 or C7.  C7-prenylation leads to accumulation of tardioxopiperazine B without further modification by echPT2.  In contrast, the C5-prenylated tardioxopiperazine A can be prenylated again by echPT2, predominantly at C7 to form echinulin or less frequently at C4 to give variecolorin L.  EchPT2 accepts also neoechilunin A to produce varlecolorin G (prenylation at C5) or isoechinulin A (prenylation at C7).  EchPT2 further converts isoechinulin A into dehydroechinulin.  Moreover, a yet unidentified enzyme can also convert neoechilunin A into neoechilunin B by introducing a double bond between positions C14 and C17 and thus provides a further substrate to echPT2 for C5 and C7 prenylation (PubMed:29072465, PubMed:33381959).
What are the official names of this protein?
Echinulin prenyltransferase 2, EchPT2, Echinulin biosynthesis cluster protein echPT2.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: FOLE_YEAS1
Sequence: MHKGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYIKFLFDLMIIKNPLRMVGKTYRDAVTALNSLQSNYANIMAIRQTGDRKNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPPFKQLENVKLGIAGEFQKSNASLAVMLASEILHTSNILEEKIKCSSNASIPEKFIIGLQNTKWEGRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDMVRLSKRKKILLFNQQSRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQESLVKNWNKIDDNRAKTHVTASIEEANELIETLYDEPADIFVTGSLHLVGGLLVVFDRIDVK
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Required for methionine synthesis and maintenance of intact mitochondrial DNA.  Involved in telomere maintenance (By similarity).
What are the official names of this protein?
Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix. Cytoplasm.
Protein: YBEY_PHOV8
Sequence: MISYQTEGVKMPDIKKKETTGWIKEVAACYGKRVGEIAYIFCSDDKILEVNRQYLQHDYYTDIITFDYCEGDRISGDLFISLDTVRSNAEQFEQPYDRELHRVIIHGILHLCGINDKGPGEREIMEAAENKALALISL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BRAHW
Sequence: MINIALPKGRLVNKVYTLFEKIGYENKELLEDNRKLVFENKDKNVRYLIVKPSDVGIYVEKGVADIGIVGKDILLENNHDVYELLDLKFGKCRVCMASVNGYKEDIERRLRVATKYVNISKNYFNSINRDVEIIKLNGSIELAPILNLSDVIVDIVETGSTLRENNLTVIKEIIDYISARLIVNKVSYKFKNDLIKTIIKNIEEVL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_LIMRD
Sequence: MAFNLRNRSFLTLADFNTREMEYMLDLAEDLKKAKYAGYEGKNLKGKNIALIFEKSSTRTRCSFEVGAKDEGAHVTYLGPSGSHIGHKESVKDTARVLGGMFDGIEYRGFSQRNVEILAKYSGVPVWNGLTDEDHPTQVLADFLTAHEVLKKPYKDIKFAFVGDGQDNVSNALMLGAAVMGMEYHVVTPKELEPTKETLDKANEIAAKTGAKIVVTNDIKEGVKGMDVIYADVWVSMGESDDMWEKRINLLKPYQVTMDVMKATENPNVLFEHCLPAFHNLDTEVGKEIEKKFGLKEMEVTDEVFESEHSVVFREAENRMHTIKAVMVATLGEQN
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CHAGL
Sequence: MADQTISNVLNQPQWRCLESKIEKSTLHYGRFIISPLWKGQANTIGLALRRTLLSEVEGTCITSVKIKNAIHEYSSLSGVQESVHDILINLKKIILSSSFSGIFEGFLSVVGPKTVLASDLNLPSFIKIVNPDQYIATVNKPINFNLQIYIQKGKGYSLKNPISIKQGFFLVDPVFIPIRSVNYSIHSFEDEKATKEFLIVEVWTNGSIEPKEAIKEASYNLVNLFTPLVSQEYQQLKNQLFKEDEKNKELNFIETNSNAISDNENSYNLYNQIFLDQLELSSRAYNSLKKNNINTISDLLKYSYEDLLKIKNFGKKSADQVIEQLKKRFKIQL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMOL1_HUMAN
Sequence: MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
What is the function of this protein?
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
What are the official names of this protein?
Angiomotin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the angiomotin family.
What are the subcellular locations of this protein?
Cell junction, tight junction.
Protein: SEC16_KLULA
Sequence: MGPDAKKRKNQKKKLKLKQKRLHASNGSADESAIVPQTTDVHLESSAEAIGSVRSVNAQVSPQSEASQADTPQLVHTEAIPDAVPEHNDLSDLFQQENNDTIANEAAVFDSIVKEQAPDVPVVAAAFTNDANVGNVGTLNNAQHVSNEITASEKAPDSVIGSMPVEAQPSVINDPVEELFGNDDTVQTEGLPWQDQIIAEELPSISAEVGRELPQQESINDYDQQEQFPPLLHDEKNTVQLDQSEREVATIENFNEPLSQVNDGRKAPNMVTLDALLDDDNDYLTSDNDTQGMEHEATPTELVSGENSSPVQPVNDAIEKATGDEDTDLFNSEGDDGAKEGLSWLNDQSNTQEIPSPSEEATKFSFLENDDDLLDDDESLLDSDEEVIVPQPQTAQAPKKSYLPSASSPVPQSVKHSYHPQSNPYSPQASSFSNSVSGQPPSFPQNPSSYTYPVASTVPASVAPGIVKPKLINNSNSSQSSVSDVNELHKKLDEAKHRTDAYDFPLDLVKQEIKRGKPMHITSPLPSIRQPSFSSVASEKPLIQPPVRPQPNNTKAPQKPFYAELPIPELKPTRAAPIRIASQNSFSGSSALPSQPIAAQSRRTSIDPPVNPYAPKKNVAVVNPTIAPNSVAYGINNVPSKGQNLQANILSAPPRNTIVSPVGTIAHNPYTPSLKSTASSSIKETPYQPAQPRRNRVLTNASADSAGSFNPGHIPPIPGVPSTESNIYSFPPQHLSTAAPTATDHLQTTFDSHNVPPVLSPTLSTTANNKKTHARSNSSIYAPAHHAHSSKYAPTVHPQFQQQQQQQHQQQHQQQQQLQQLQLLQQQQQQQQQQQQLNGIPVGFPRSQVDSNYGYASQQNTNQPIASTFPIMDQSRNPSIQANGSYIVSRQFPIFHWGKSAKVVVGIPNTQDYISAVEPKLDSINVISNDSILTLDKTLEQFPGPLIKGKSKSKDIAKWLDTYIEEKKLKGANDTCILLELLKLRLDPSYSLKAVTNIIYDSSILLPYLSQPFIPKVAAPNAHKLDANSLIRVLTLLQTGAHDDALNLSLALKDYAMALLLGSILGKEKWSSVVDQYLTQEFEQSNERDISSINLLATIFQVFIGNSKKVIDSFKQDPTKLEWSLNNWKLLIACILNNCEEVPANGKLSPIVVEFLLQFGELLVSRGLVIAGSIAFIVADIPMSEEPLIPFSSTTFEYICCPNSFESLILSEIYEFTYGQKDPSFSGFTSLIPQKIIHAAGLSDYGLNSSSTKYMDMAQSMLKSLPKNSETTLKTLRYIEDLSNQLSSSNVGWLGKPKLSSVWGQLDKSFNKFIGGDTDIDESETAAIEDKVFEKFTPTSSRNPSMADLSQAASYLTPALNRSHINQLQSNNSSLIKSTTKILPASSLPSRETHSKYGPPPLRDMKPQSKIGELYGSHSNIEPLNSTASARNTVHPSHFEEPDNYVNPSGATSLGQKELPNSNSTPEPVLPPLAQVYPGYQIHHDLSDGNSSVSSGHRLYSKMGVPNQNTASFCVPSPIVSPQSTKHQSSTSNKALPLENLFDDTVTSGLTTESTQTGSNAPPRFHENEQHSVVDDIVEEIGNEIDAELDELQHSEFSDDNNFESTEQNSISGVEGSVSQLNVTNQLPVAENLQEEDKNQVTDINVPVTQAQPLNSFSPASSISSKPSSLKNMSVDKAEPANPYAPKNSFGVAPRTARKSYNPYSPSSITESHSMASLPQTSTSPYNNDNNSAPVNETGGPEDLAMYAYGSYKLSGEDAKPQTIDSPNGQKQEIENKTSSPPLNSFVPSNIGLGENLISVKSIGLPAHLQNDSQTLPSSKIKDPVIRPVQTSNFVPFIVSDTNTEEYYDDLVEDTEDEDEDEPISVKREISERNSENQNQKVKNDEDEDEVKTVSEDEAGKPDKKQKNESSGGWLGWFKKDSNEKKPIKAKLGHANNFYYDENLKRWVNKDATEEEKLKVATPPPPPPVVKRKMSKTPEIKPRQGSVVGGPALRTAHAVMPTNPLTGKPLDPVKDFSDDAETKSESPVSSKPPVSNTNVNLSGSKANGLDDLMALTGGVSSASSTRRKKKSTRGYVNVMENL
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACSF4_HUMAN
Sequence: MTLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIREIGLYCQPGIDLPSWILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIEKLVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDVTFRKSCATKRKLSDINQEEASGTSLHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVSQTNIQNLKGLNSPVLIGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDASPLVVIPTFDKSSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFSSPCLNLIPHHLYFATLGGLLLAVNPATGNVIWKHSCGKPLFSSPQCCSQYICIGCVDGNLLCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIYCCNMKGHLQWKFETTSRVYATPFAFHNYNGSNEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLIIGCRDNYVYCLDLLGGNQK
What is the function of this protein?
Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor.  May be required for a post-translational protein modification or for post-transcriptional modification of an RNA.
What are the official names of this protein?
Beta-alanine-activating enzyme, Acyl-CoA synthetase family member 4, Protein NRPS998.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CSPLA_SOYBN
Sequence: MMEKGSVVEAAVTRSPMQMKMGDHELEGNTTSALRTAETFLRLFPVGLCVSALVLMLKSSQQNEYGSVDYSDLGAFRYLVHANGICAGYSLFSAVIAAMPCPSTIPRAWTFFLLDQVLTYIILAAGAVSTEVLYLAENGDAATTWSSACGSFGRFCHKVTASVAITFVAVFCYVLLSLVSSYKLFTKYDAPASRPTEAIEVAAFPG
What are the official names of this protein?
CASP-like protein 2A2, GmCASPL2A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAAR5_HUMAN
Sequence: MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
What is the function of this protein?
Olfactory receptor specific for trimethylamine, a trace amine.  Also activated at lower level by dimethylethylamine.  Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food.  This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
What are the official names of this protein?
Trace amine-associated receptor 5, TaR-5, Trace amine receptor 5, hTaar5, Putative neurotransmitter receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PXPA_ALBFT
Sequence: MKMDLNSDLGESLGAWRMGDDAAMLGIVSSANVACGFHAGDPAGVLRTLRRARDNGVVVGAHVAYRDLIGFGRRNMDVESADLIADVIYQIGALKGLAAAAGTSVRYVKPHGALYNTIAHDARQAHDVITAIREVDPRLTLVALAGSPLLGWAQDQGLRVVAEAFADRAYTPAGTLVSRREKGAVLHDAKLIAERMLRLVSDGVIEAIDGSLVAIAADSICVHGDNPDAVAVAAQVRTRLTQAGVSIQSFEVAAP
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: LEPA_PELUB
Sequence: MTKIDHIRNFAIIAHIDHGKSTIADRIIHSCGGLTEREMKAQVLDSMDIERERGITIKAQTVKLNYKAKDGKDYILNIIDTPGHVDFSYEVSRSLYACEGSILIVDSTQGVEAQTLANVYQALDTKHEIVPVLNKVDLPASDLEKTKKQIEEVIGIDTENAIPCSGKTGEGIEDILEQIIVSLPAPEGEKDADLKCLLVDSWYDTYLGVVILVRVINGKISKNMKIKMMSTDQEYIIEKVGVFTPKATDVNELNAGEIGFITTGIKILSETKVGDTICDATKPPQEALPGFKPSKPVVFCGLFPVDSSEYQKLKDGLGKLQLNDASFSYEAESSSALGLGFRCGFLGLLHLEIITERLEREFDINLLTTTPGVVYKVHMNKGDIIELQNPSSLPEPTLIKFIEEPWIKATIITPDQYLGAIIKVCQDKRGVQTNLSYSGNRAVLNYEIPLNEVVFDFNDRLKSMTSGYASFDYEIIGHREGDLVKLGILVNAEPVDALSMMVHKDFAQTVGREVCEKLKDLIPRHNFMIPVQAAIGGKIIARETIKGFKKDVLTKIHGGGARDRKRKLLDKQKKGKARGKQFGKVEIPQEAFIGVLKINKDQ
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPB4_PHANO
Sequence: MAPQTKIDRSFSALTPALSEWIIDAVDAMGFVKTTPVQHAAIPMFMKNSDVVVEAVTGSGKTLAFLIPIVERLLREDAPTKKHHVGAIIISPTRELATQIHTVLSSLLKFHAPSAAMLEPDDEDTDMEDADTPPKPTFPPGTLKAVPQLLLGGSVTPAQDLSAFLKKSPNILIGTPGRLLELLRSPHVHCPQSSFDALVMDEADRLLDLGFKEDLQKIISRLPKQRRTGLFSASMSEAVDQLIRVGLRNPVRIAVKVKARATGEDGKIEDKRTPASLQMSYLVTPPSHKIPAMKKILSSLQPQPQKSILYLSTCFSVDYFQHVLPEVLQGYDIVPLHGKHPDKVRRKNFNKFVDSVTPSILLTTDVAARGLDIPSVDLVFQLDPPSDPKTFIHRCGRAGRAGRRGLAVTFLNPGREEDYIEFLQVRQTPISPLTTPEITVTDEDAKAVTSKIRKKVREDRALFDKAQRGFVSWVRAYSKHTASSIFRIDDLDWTELGNAWGLLTLPGMPELKKWQGDKRLGIELDLATYAYKDKAREKLRLEELERDKEEGTKKKQHKKEDREKSAWTEQKESKATKEVRREKKKSKREHERLAKMTDEERKEEDRVQAMIEQMRKKVAKQEAEDADFEGFSD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YCM2_SCHPO
Sequence: MHFTLFLYFDAIRHANQRRWCHECTIKIFRRSFDIARHTVHLCVRKIFSLHPLTETDFLPNELRSEEDQTLIGIFWFLPPIIEGEDERSRFPRRSMSENHLIITKKSLHNVASKDYIRGSHVPCFQPYEDVYELNIEE
What are the official names of this protein?
Uncharacterized protein C13B11.02c.
Protein: RS9_BRUME
Sequence: MAESINSLEELGTVAKTEAAAPVDVQKLDAQGRAYATGKRKDAVARVWVKPGTGKITVNDKEFEKYFARPVLQMILQQPIVASNRAGQFDIVATVAGGGLSGQAGAVRHGISKALTYYEPGLRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PETN_SKECO
Sequence: MDIISLGWAGVMTMFTFSLALVVWGRNGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TBATA_HUMAN
Sequence: MATDVQLADYPLMSPKAELKLEKKSGRKPRSPRDSGPQKELVIPGIVDFERIRRALRTPKPQTPGTYCFGRLSHHSFFSRHHPHPQHVTHIQDLTGKPVCVVRDFPAPLPESTVFSGCQMGIPTISVPIGDPQSNRNPQLSSEAWKKELKELASRVAFLTKEDELKKKEKEQKEEPLREQGAKYSAETGRLIPASTRAVGRRRSHQGQQSQSSSRHEGVQAFLLQDQELLVLELLCRILETDLLSAIQFWLLYAPPKEKDLALGLLQTAVAQLLPQPLVSIPTEKLLSQLPEVHEPPQEKQEPPCSQSPKKTKISPFTKSEKPEYIGEAQVLQMHSSQNTEKKTSKPRAES
What is the function of this protein?
May play a role in spermatid differentiation.  Modulates thymic stromal cell proliferation and thymus function.
What are the official names of this protein?
Protein TBATA, Protein SPATIAL, Stromal protein associated with thymii and lymph node homolog, Thymus, brain and testes-associated protein.
What is the protein family that this protein belongs to?
Belongs to the TBATA family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: AMYP_PIG
Sequence: MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL
What are the official names of this protein?
Pancreatic alpha-amylase, PA, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: FDHE_SALHS
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLDH2_PSEPU
Sequence: MTQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDSSWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLAADSGVTIDERGYIFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHKAQMNYDLIPSVIYTHPEIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGGAIHVANRKKR
What is the function of this protein?
Also acts in the glycine cleavage system.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of 2-oxoglutarate dehydrogenase complex, Glycine oxidation system L-factor, LPD-GLC.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA2_LACLA
Sequence: MEKTLAVNAGSSSLKWQLYEMPEETVIAKGIFERIGLSGSISTTKFNNEEHFRKQEIVDHRQAVLLLMDELIHFKLIHEFREITGIGHRVVAGGEFFKTSTVISPEVLAEIKNLSTLAPLHNPANVLGIEAFQRLLPDALAVAVFDTAFHSTLPEKAYRYPIPTKYYEDYSIRKYGAHGTSHMYVAQEAEKVLGKPLEDLKLITAHIGNGASITAIEAGKSVDTSMGFTPLAGVMMGTRAGEMDASVIPYMLESDPSLRNAQDVIDILNKDSGVLGVSELSSDMRDLSEAVAKGNPKAILAYEMYVDRLKKFIAQYFGVLNGADALIFTAGVGENDTAVRTDVVNGLSWFGMEIDESKNVRGAFGIISKPESKVKVLVVPTNEELVIARDVEAAK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 2, Acetokinase 2.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_DESVV
Sequence: MARPKRTVKKREKKNVPVGLAHIQATFNNTIVTFTDTRGNTISWASAGQSGFKGSRKSTPFAAQMAAEQAAKKAQENGMRTVGIYVKGPGSGREAAMRAINAAGFKVAFIRDITPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.