PharMolix/UniProtQA huggingface dataset:
Protein: LON_BACAH
Sequence: MYCNIKWLNRSLIYYGGAMSSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLADLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGDKEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPWTDATEDMIDLAHSEEILNKDHYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKTSLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAKSVNPVFLLDEIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLLDRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVRTLERQIAKVCRKAAKIIVTAERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAYTAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFSYIRSRAEELQIDPDFHEKNDIHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKTLSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SHEPC
Sequence: MGDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDSDKLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNSSPKDGVELGKSNILLIGPTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKDKATISETLSQVEPGDLVKYGLIPEFIGRLPVVATLTELDEEALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIAHKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVDESVVNGESAPILIYEHNETQAASGEQ
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL15_SYNPW
Sequence: MTLRLESLKSNKGARRRKLRKGRGIAAGQGASCGFGMRGQKSRSGRPTRPGFEGGQMPLYRRVPKLKHFPLVNPKQFTVVNVSALNDLKAGSTVSLDSLVKDGIVTSPKHPLKILGNGELKTKLTVQAAAFTASARTKIEAAGGTCELPE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RS10_CAMJE
Sequence: MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPIPMPTKIKRYTVLKSPHINKDSREQFEIRIHARMLDIVAATPDTVDSLTKLDLAPEVSVEVRAMGK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MATK_MEDTR
Sequence: MKEYQVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFLENVGSDSKYSLLIVKRLITRMYQQNHLIISANDSNKNPFWGYNKNIYSQIISEGFAIVVEIPFFLELSSSLEEAEIIKSYKNLRSIHSIFPFLEDKFTYFNYVSDIRIPYPIHLEILVQILRYWVKDAPFFHLLRLFLYNFSNWNSFITTKNSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFNVFFERIFFYAKREHLVEVFAKDFSYTLTFFKDPLIHYVRYQGKCILASKNSPFLMNKWKHYFIHLWQGFFYVWSQPRTMNINQLSEHSFQLLGYFLNVRVNRSVVRSQMLQNTFLIEIFNKKLDLIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIDRFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSSTLHRLNRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNAS1_CRIGR
Sequence: VQPSLGKESAAMKFERQHMDSTVATSSSPTYCNQMMKRRNMTQGQCKPVNTFVHESLADVHAVCSQENVKCKNGKSNCYKSHSALHITDCRLKGNAKYPNCDYQTSQHQKHIIVACEGNPFVPVHFDATV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_BACAH
Sequence: MTMSHLLTMSELSEVEISEILKDAEDFANGKESKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLDVLNFSADASSVQKGETLYDTIRTLESIGTKAVVIRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLQIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEDNTFGTYKPLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHEKHGLTVEREKRMKEGSIIMHPAPVNRDVEIASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELLV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CYC2_XENLA
Sequence: MGDVEKGKKVFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGIVWDEDTLMVYLENPKKYIPGTKMIFAGIKKKGERQDLIAYLKQSTSS
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c, testis-specific.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: BCHD_CHLP8
Sequence: MIAFTDIVGMDLAKQALMLLAVDPSLGGVVIPSTVGSGKSTLARAFADILPEGTPFVELPLNVTEDRLIGGVDLEATLASGQRVVQHGVLSKAHKGVLYVDSLSLLDSSAVSHIMDAMSRGAVIVEREGLSEVHPADFMLVGTYDPSDGEVRMGLLDRIGIIVPFTPVNDYRARKQIVSLVMGTRNEEDTQDELRMLRGIIGAAREQLHHVSITNEQIKGLIQTAISLGVEGNRVDIFAIRAALANAALGQRTEVDDEDLKLAVKLVLVPRATRMPEREPSEEEMQQEEPPPPEEQPEQEGEDENAPPDETDSDADEEQEETPDMIEELMMDAIETDLPENILNISLASKKKAKSGSRGEALNNKRGRFVRSQPGEIKSGKVALIPTLISAAPWQAARKAEKAKKGIKTGALVISTDDVKIKRFRDKSGTLFIFMVDASGSMALNRMRQAKGAVASLLQNAYVHRDQVSLISFRGKQAQVLLPPSQSVDRAKRELDVLPTGGGTPLASALLTGWETAKQARTKGITQIMFVMITDGRGNIPLAAAVDPAAAKAPKEELEKEVEALALSIQSDGIASIVVDTQMNYLSRGEAPKLAQKLGGRYFYLPNAKAEQIVEAALS
What is the function of this protein?
Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase 67 kDa subunit, Mg-chelatase subunit D, Mg-protoporphyrin IX chelatase.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
Protein: YBEY_SHEON
Sequence: MSLDLALDVQYATTSDYLPSEEQLALWVKTAIGNSMKQAELTIRIVDARESQMLNGTYRGKDKPTNVLSFPFEAPPEIELPLLGDLVICASVVENEAREQDKTLEAHWAHMVVHGCLHLLGYDHIEDEEAEEMESLETQLIESLGFTDPYKEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF312_ARATH
Sequence: MSCFSFLVYFLLFIVTKMSQSPLSQSSHEFTVVSPYLSCFGIEECLFYLYFKLYDLCVILLCTWFDLSE
What are the official names of this protein?
Putative defensin-like protein 312.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAA_ECO8A
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: COAD_LEPIN
Sequence: MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTKGMKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_SHEFN
Sequence: MSSNQELVVLGKLGSSHGIKGWLKITSYTDSVEGIFDYSPWLIKEQGVWREVKVAQWRFQGKAVVAELEGVATREHAQMLTNCEIAIMPEQMKDLDDSEFYHRDLIGCEVTNINGYNMGIVDQIVETGSNDVLLIKANAKDAFGKAERMIPFVPEQFIKQVDLQGKQILVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCH_PYRAB
Sequence: MKRWEHYEHTADIGIRGYGDSLEEAFEAVAIALFDVIVNVNKVEKKEVREVEVEGEDLESLLYNFLEELLVIHDIEGLVFRDFEVKIEKTEKGYKLKAKAYGEKLDPEKHEPKEEVKAITYHDMKIEKLPDGRWMAQLVPDI
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).  Chaperone or modulator of proteins involved in DNA or RNA processing.  Protects the tRNA (cytosine-5-)-methyltransferase PAB1947 against aggregation and increases its specificity.
What are the official names of this protein?
Protein archease, tRNA m5C methyltransferase chaperone.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: RS17_WOLSU
Sequence: MSNEQAHKRVIQGKVVTKAGDKSVTILVERRVTHPKYRKIVKRFKKYIVHDESNAVKVGDMIEAIECRPLSKRKSFSLHKVLSVGVEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ATG13_VANPO
Sequence: MAPHNCDRELIDLIHNFFLRSTLLICSSKLNKNQHLLEEIQKFDSDLNEKPDLPKTINEWFHDENERNLPPLVIETLLDLKKLSPNHFVTLRDDDGNVWNVCKGTKKSEIVLERWLIELDNTSAAFQSYRGTIDSTGEIRKQIVLLARYLVTLIQILPSNELEENLTKNSTNLILSLKRKVIDGSKPILSKGRIGLSKPIISTYSNVINERNIPPHLEQRKITPVYTPLGLLRISVSFRHDCRFEVNQSTDSSDNVASNTTNIHQHLEPLHNKNYTNTSLSISPHSHIALASSSERNSIGKKDLNSKPIHPFKTGSVGSCTINQSQAMIRTTSNPSVIATLRAQRSRNDSISCQSQLEDIQLESTSVGSGSKYSSSFGRIRRHSSVKSSENVEKPIRLVKQSNAPTDDLLDFVKMMDEKQELRITKCNISSNNADISNSILRFQKLKSSNEILSEDLSMSVSLEGVNASMHRRSSVSHSPIPSVSPPVQYPSIPSRLSKTNLQEQDTFKTAVVSRRNSVEKSKINISQPKTTGRIENELVDKPLFNEEHESKGEELLASGIIGPSFKRSTSPHSIESVSSLISKTKIAFQQPSYYSHPTTAAVPAYAKLHRPSVLSTDVLSEDQNKKVVQDLNNNKDEDDELLFFMSDMNLSKI
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: BLUB_RHIME
Sequence: MLPDPNGCLTAAGAFSSDERAAVYRAIETRRDVRDEFLPEPLSEELIARLLGAAHQAPSVGFMQPWNFVLVRQDETREKVWQAFQRANDEAAEMFSGERQAKYRSLKLEGIRKAPLSICVTCDRTRGGAVVLGRTHNPQMDLYSTVCAVQNLWLAARAEGVGVGWVSIFHESEIKAILGIPDHVEIVAWLCLGFVDRLYQEPELAAKGWRQRLPLEDLVFEEGWGVR
What is the function of this protein?
Involved in the biosynthesis of cobalamin (vitamin B12).  Catalyzes the oxidative fragmentation and contraction of the isoalloxazine heterocycle and the cleavage of the ribityl tail of FMN(2) to form 5,6-dimethylbenzimidazole (DMB) and D-erythrose 4-phosphate (E4P).  NAD(P)H is only required initially to reduce FMN and oxygen drives the oxidative fragmentation.
What are the official names of this protein?
5,6-dimethylbenzimidazole synthase, DMB synthase.
What is the protein family that this protein belongs to?
Belongs to the BluB family.
Protein: PHF5A_RAT
Sequence: MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR
What is the function of this protein?
Involved with the PAF1 complex (PAF1C) in transcriptional elongation by RNA polymerase II, and in regulation of development and maintenance of embryonic stem cell (ESC) pluripotency.  Required for maintenance of ESCs self-renewal and cellular reprogramming of stem cells.  Maintains pluripotency by recruiting and stabilizing PAF1C on pluripotency genes loci, and by regulating the expression of the pluripotency genes.  Regulates the deposition of elongation-associated histone modifications, including dimethylated histone H3 'Lys-79' (H3K79me2) and trimethylated histone H3 'Lys-36' (H3K36me3), on PAF1C targets, self-renewal and pluripotency genes.  Regulates RNA polymerase II promoter-proximal pause release of the PAF1C targets and self-renewal genes, and the levels of elongating ('Ser-2' phosphorylated) RNA polymerase II in their gene bodies.  Regulates muscle specification in adult stem cells by stabilizing PAF1C in chromatin to promote myogenic differentiation (By similarity).  Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex.  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (By similarity).  Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha (PubMed:12810571).
What are the official names of this protein?
PHD finger-like domain-containing protein 5A, PHD finger-like domain protein 5A, Splicing factor 3B-associated 14 kDa protein, SF3b14b.
What is the protein family that this protein belongs to?
Belongs to the PHF5 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: FEN1_OSMMO
Sequence: MGIHGLAKLIADQAPGAIKEQEMKNFFGRKIAIDASMCIYQFLIAVRQDGNVLQNEDGETTSHLMGMFYRTIRMLENGIKPVYVFDGKPPQLKSGELEKRGERRAEAEKLLAQAQEAGEQENIDKFSKRLVKVTRQHNDECKKLLTLMGVPYVEAPCEAEASCAALVKAGKVFATATEDMDGLTFGTGVLLRHLTASEAKKLPIQEFHFSRILQDIGLSHEQFIDLCILLGCDYCGTIKGIGPKRAMDLIRQHGSIEEILDNIDLSKHPVPEDWLYKEARGLFLTPDVVDCSCLELKWSEPDEEGLVQFMCAEKQFSEDRMRNGCKKILKSRQGSTQGRLDSFFSVTGSLSSKRKEPEMKGSTKKKLKTGATAGKFKKGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: Y3721_PSEAB
Sequence: MPEPTFHELAQLPPPVLRQLIRRGDYAGHTSGLGQRHLQANLVILQKSWADEFLRFCALNPRACPLLDVSEPGSPHFARLGADIDVRSDLPRYRVHRRGQEPVEVNDIGAFWEADFVAFAIGCSFSFEQALLDAGIGLRHLELGRNVAMYRTAIATRPSGRLAGPTVVSMRPLKAAEAIRAIQITSRFPMTHGAPLHLGDPALIGIRDLARPDYGDPVPLAADEIPLFWACGVTPQAVLAEAQPELYISHAPGHMLVSDRLYDEL
What are the official names of this protein?
Putative hydro-lyase PA14_37210.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: FYV6_CANGA
Sequence: MSEEKKLQFVTEGQADVEKQSEREEAIQGAIETERKKRVRKTLRDQLRANAIKKQKKSNRESAEVKKLNQLSKEETRYFKELEKNREQEIQRLTQFHKDKDYEYEKKRQQLLSRSPDKQSGKPDTLSSNQNNGSTERVILKVKNKNRPRLVVKK
What is the function of this protein?
Involved in telomere length regulation and promotes fully efficient non-homologous end-joining (NHEJ) by a mechanism activated in postdiauxic/stationary phase.
What are the official names of this protein?
Protein FYV6.
What is the protein family that this protein belongs to?
Belongs to the FYV6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: Y186_STRPJ
Sequence: MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVGYVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL
What are the official names of this protein?
UPF0297 protein SPN23F01860.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: SSRP_SYNE7
Sequence: MADSGGIKVLSENRQARFQYEILETFETGIELLGTEVKSIRAGKVNLRDGFALVRNGEVWLHNIHISPHQQASAYYNHDPLRTRKLLMHREEIRKLIGKVEQKGLTLVPLKMYLKQGWVKVTLGLGRGKKLHDKRETERRRQDQRDIQRAIKRA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NOSIP_DANRE
Sequence: MTRHGKNCTAGAVYTYHEKRKDTAASGYGTQSVRLGKDAIKDFDCCSLSLQPCRDPVLTEDGYLYEKEAILQYILHQKTEIAKKMKAYEKQKQALKSEGQLESKSEERERAEKFKQRENNIVSKPINPFTSGKSKDEGNQNGSTSSSSTDTSSGESSSSSALPSFWIPSLTPEAKPTLLKKPSKTVSCPMSGRPLKMSDLITVRFTPLDPSLDRVALLTRQDRYVCAVTKDTLGNSVPCAVLRPSGVVVTMECVEKLIKKDMVDPITGDKLKEKDIIPIQRGGTGFAGSGVDLKAKEARPVMQA
What is the function of this protein?
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face (By similarity).  Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity (By similarity).
What are the official names of this protein?
Nitric oxide synthase-interacting protein, E3 ubiquitin-protein ligase NOSIP, RING-type E3 ubiquitin transferase NOSIP.
What is the protein family that this protein belongs to?
Belongs to the NOSIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.
Protein: APHA_MARMS
Sequence: MNHTLRSITLVLACVASLSANADPKTPGTHKGYSTIDMTTAGMPADVKMISVADIQKELQGKAPFAVGFDIDDTTLFSTPVFYRGQQEFSPNGYSYLTNQDFWDKANCGWDAFSMPKNIAKELIAMHQERGDSIYFITGRTGSDCNFTTEYLKKTFDIKDMHDVIFAGSSRTEYTKTKYIKNNDIKIYYGDADGDIISARDAGAEGIRVMRAANSSYTPIPKNGIYGERVLKDSQY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters.  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DHAS1_VIBCH
Sequence: MRVGLVGWRGMVGSVLMQRMVEERDFDLIEPVFFSTSQIGVPAPNFGKDAGMLHDAFDIESLKQLDAVITCQGGSYTEKVYPALRQAGWKGYWIDAASTLRMDKEAIITLDPVNLKQILHGIHHGTKTFVGGNCTVSLMLMALGGLYERGLVEWMSAMTYQAASGAGAQNMRELISQMGVINDAVSSELANPASSILDIDKKVAETMRSGSFPTDNFGVPLAGSLIPWIDVKRDNGQSKEEWKAGVEANKILGLQDSPVPIDGTCVRIGAMRCHSQALTIKLKQNIPLDEIEEMIATHNDWVKVIPNERDITARELTPAKVTGTLSVPVGRLRKMAMGDDFLNAFTVGDQLLWGAAEPLRRTLRIILAEK
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase 1, ASA dehydrogenase 1, ASADH 1, Aspartate-beta-semialdehyde dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: DEF_MYCSJ
Sequence: MAVVPIRIVGDPVLRTETTPIPVGDDGSLPAEVADLIRDLYETMDAANGVGLAANQIGVSQRVFVYDCPDSRGRAGRRRGVVINPVLETSDIPETMPDPDDDEEGCLSVPGEQFPTGRADWARVTGLDADGSPITVEGTGLFARMLQHETGHLDGFLYLDRLIGRHARAAKRAVKHNGWGVPGLSWTPGEDPDPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.