PharMolix/UniProtQA huggingface dataset:
Protein: MYO7B_HUMAN
Sequence: MSGFRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEPEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLDQQEKMLLELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLKERSIFAMALQDRKATDDTTLLAFKKGDLLVLTKKQGLLASENWTLGQNDRTGKTGLVPMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLSAMNKQRGSKAPALAST
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.  As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length.  May link the complex to the actin core bundle of microvilli (Probable).
What are the official names of this protein?
Unconventional myosin-VIIb.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Enriched in the microvilli of the intestinal brush border.
Protein: SNXAA_DANRE
Sequence: MDNTSFEKREFISVWVRDPQVHKEDFWHTYISYEICLHTNSMCFRKKTSCVRRRYSEFVWLRHKLQDNALLIELPKLPPWNPFFNLNNEFHITQRMQGLQQFLEAVLQTPLLLSDSRLHLFLQSQLSIAKMDACAQGHTHYTVAQAIQRCGGEARFPVEEQHQEDSKTCCDSDCDSTTSSGLGCSIEPATLVEQDLSHNERFAHEFQATNPEAELCSSLSSSPHGHSVI
What is the function of this protein?
Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes.  May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.
What are the official names of this protein?
Sorting nexin-10A.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SSUB_PSEE4
Sequence: MTVLKEQPPRLLRGIPLAANDLRRTFGQREVLRGVDLHIPAGQFVAIVGRSGCGKSTLLRLLAGLDQPSGGELLAGAAPLAEAREDTRLMFQDARLLPWKKVIDNVGLGLSGNWRPRALEALDAVGLAERAHEWPAALSGGQKQRVALARALIHQPRLLLLDEPLGALDALTRIEMQQLIERLWRQHGFTVLLVTHDVSEAVAVADRVILIEDGAVGLDLVVDLPRPRVRGSHRLAALESEVLNRVLSVPGTPPEPEPVAPLPTHLRWAH
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VPU_HV1Z2
Sequence: MQPSQIIAIAALVVAAIIAIVVWTIVFIEYRRIKRQRKIDCIIDRIRERAEDSGNESEGDREELSKLVEMGHHAPWDIDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: CSPLJ_ARALL
Sequence: MKMKRTVSSNSEAYSYNESPHSPLRFHSPLSDAGDLPESRYVSPEGSPFKIENPKSIVAGNKLTQFSPLPSPIPPPPPQIPPPRRQRNARVPMNSSLDKSPSSMVVQNSWVREDGQQNTTRKAGAPMNGEESATTAVNRARRDDLVSVTALGFRITEVILCVISFSIMAADKTQGWSGDSYDRYKEYRYCLAVNVIAFVYSAFEACDAACYMAKESYMMNCGFHDLFVFSMDQLLAYLLMSASSCAATRVDDWVSNWGKDEFTQMATASIAVSFLAFGAFAVSALISSYRLFTHASS
What are the official names of this protein?
CASP-like protein 4A2, AlCASPL4A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGSY_MYCTO
Sequence: MRILMVSWEYPPVVIGGLGRHVHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRTGPAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR
What is the function of this protein?
Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans.  Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen.  May also use ADP-glucose as substrate (By similarity).
What are the official names of this protein?
Glycogen synthase, Alpha-1,4-glucosyltransferase MT3116, UDP-glucose--glycogen glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
Protein: RL3_DESVM
Sequence: MAEKLGILGRKVGMTRIFASDGSAVAVTVIQAGPCPVIQVRNGETDGYDAVQIAFEEAKEKHVTKPARGHFAKAGKGLFRNLREIRLEAPAEFEVGQELTVSLFAAGEKVKVTGTSIGKGYQGVMRRWNFAGSKDTHGCEKVHRSGGSIGNNTFPGHVFKGKKMAGHWGDERVTVKNLEIVDIRAEDNVILVKGAVPGPKNGLVLVRKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: B2MG_GORGO
Sequence: MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
Protein: SWM_DROME
Sequence: MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFVERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNVIKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDHKTKDSHNQQSASNYQHHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFNPTAVTTPLQRQLIPIPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPINSRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPTPNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQRAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQRNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR
What is the function of this protein?
Negatively regulates Hedgehog (hh) protein signal in wing development (PubMed:18245841).  Regulates neural-specific glycosylation by binding to FucTA mRNA and facilitating its nuclear export in neural cells (PubMed:21203496).
What are the official names of this protein?
Zinc finger protein swm, Protein second mitotic wave missing.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS2_BIFLO
Sequence: MKTFESLFAELSEKAQTRPEGSLTVDELDKGTHFIGKKIIEEAGETWMAAEYEGADRTAEEMSQLLYHVQVMMIKHGLTLEDVYKHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_THISH
Sequence: MSIHQVMRYLPHRYPFLLVDRVTDFKPGEYLEAIKNVSINEPYFQGHFPIRPVMPGVLIMEALAQATGLLAFKTEEARNENQDKQQLYLFVGIDEARFRRQVEPGDQLHLRVELLRVVRGIWRFKAEARVNGDLVASATLMCAGKEIES
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WBP1L_RAT
Sequence: MPFLWGLRQDKEACVGTNNQSYICDTGHCCGQAQCCSHYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQGGPAGGSPPGADQPQGSQGAQSSPLSGPSRSSTRPPSVADPQSLEVPTERAATKALGMESSSSVASHGELDPGAFLDRDSECKEELLKDSSSEHGGAPPDSKDKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPVDEEEGLCLSSEGQAREHGHPHLPRPPACLLLNTINEQDSPNSQRSSSPS
What are the official names of this protein?
WW domain binding protein 1-like, Outcome predictor in acute leukemia 1 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YCLC_BACSU
Sequence: MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGASARAASNLGDKSPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVKREETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGIYRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQSEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWALSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPLTTKEWEQKLMDLMNK
What is the function of this protein?
Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:15979273, PubMed:18388975).  Phenolic acid decarboxylase that catalyzes the reversible decarboxylation of 4-hydroxybenzoate and vanillate (PubMed:15979273, PubMed:18388975).  Could also catalyze the decarboxylation of salicylate (Probable).  Is not active on di- and tri-hydroxybenzoate derivatives (PubMed:18388975).
What are the official names of this protein?
Phenolic acid decarboxylase, PAD, 4-hydroxybenzoate decarboxylase, 4-hydroxybenzoate DC, Phenolic acid decarboxylase subunit C, Vanillate decarboxylase, Vanillate DC.
What is the protein family that this protein belongs to?
Belongs to the UbiD family. YclC subfamily.
Protein: BT2_ARATH
Sequence: MEAVLVAMSVPATTEDDGFSLITDKLSYNLTPTSDVEIVTSDNRRIPAHSGVLASASPVLMNIMKKPMRRYRGCGSKRVIKILGVPCDAVSVFIKFLYSSSLTEDEMERYGIHLLALSHVYMVTQLKQRCSKGVVQRLTTENVVDVLQLARLCDAPDVCLRSMRLIHSQFKTVEQTEGWKFIQEHDPFLELDILQFIDDAESRKKRRRRHRKEQDLYMQLSEAMECIEHICTQGCTLVGPSNVVDNNKKSMTAEKSEPCKAFSTCYGLQLLIRHFAVCKRRNNDKGCLRCKRMLQLFRLHSLICDQPDSCRVPLCRQFRKRGEQDKKMGEDTKWKLLVTRVVSAKAMTSLCQSKKNKCEQAQGV
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Plays a key role as a component of the TAC1-mediated telomerase activation pathway certainly by targeting a telomerase repressor to degradation.  Seems to occupy an integral position in a complex signaling network that perceives, integrates, and responds to multiple, and sometimes competing, signals.  Enhances responses to auxin in postgermination and vegetative development.  Also negatively regulates ABA- and sugar-mediated inhibition of the germination.  Essential for female and male gametophyte development.
What are the official names of this protein?
BTB/POZ and TAZ domain-containing protein 2, BTB and TAZ domain protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y1240_STAAC
Sequence: MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
What are the official names of this protein?
Uncharacterized protein SACOL1240.
Protein: NLPC_ECOLI
Sequence: MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI
What are the official names of this protein?
Probable endopeptidase NlpC, ORF-17, Probable lipoprotein NlpC.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MNS1_YEAST
Sequence: MKNSVGISIATIVAIIAAIYYVPWYEHFERKSPGAGEMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMPRGNQPLGWIIVDSVDTLMLMYNSSTLYKSEFEAEIQRSEHWINDVLDFDIDAEVNVFETTIRMLGGLLSAYHLSDVLEVGNKTVYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQAVKNHADGGASSTAEFTTLQMEFKYLAYLTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSRGDSFYEYLLKQYLLTHETLYYDLYRKSMEGMKKHLLAQSKPSSLWYIGEREQGLHGQLSPKMDHLVCFMGGLLASGSTEGLSIHEARRRPFFSLSLERKSDWDLAKGITDTCYQMYKQSSSGLAPEIVVFNDGNIKQDGWWRSSVGDFFVKPLDRHNLQRPETVESIMFMYHLSHDHKYREWGAEIATSFFENTCVDCNDPKLRRFTSLSDCITLPTKKSNNMESFWLAETLKYLYILFLDEFDLTKVVFNTEAHPFPVLDEEILKSQSLTTGWSL
What is the function of this protein?
Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation.  It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations it further trims the carbohydrates to Man(5)GlcNAc(2).
What are the official names of this protein?
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ER alpha-1,2-mannosidase, Man(9)-alpha-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: CLRD_IDEDE
Sequence: MNTLIDNPKAMASGYLAMAQMFSYPDADAWRRLTENGLVDPALGRETLEAEYLGLFEMGGGTSTMSLYEGQNRPERGRDGILQELLRFYEFFDVHLNQDEREYPDHLVTELEFLAWLCLQEHAALRDGRDAEPFQNAARDFLVRHLAAWLPDFRQRLEATETTYAQYGPTLGELVETHRSRLGDQPQKSREMQ
What is the function of this protein?
May function as a system-specific chaperone protein essential for the assembly of an active chlorate reductase ClrABC.
What are the official names of this protein?
Chlorate reductase assembly chaperone protein.
What is the protein family that this protein belongs to?
Belongs to the type II DMSO reductase enzyme chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPOA_KLEP7
Sequence: MVPSTFLRSKPARCLPVLLATLIFAGCGTHTQDQSAAFMQGTSQANSSFYLQQMQQSTNDSKTNWQLLAIRALLQEGKKQQAIDLFNQLPANLNSTQAREQSLLAVEVKLAQNDYQAARNLLAKIDPTNLEQPQQARYWQAQIDASQGKPSLTLLRALIAQQPLLSDAKQRQKNIDATWQALTSMPQDQANALVINADENILQGWLDLQRMWFDNRNDPTLLKAGVKDWQTRYPQNPGAKMLPTALVNMQNYKPASINKIALFLPLNGQASIFGRTIQQGFEAAKNGAPSVTGSAVPAQVAQAANVSGNDDVVSPSQAEISDLTATGSRADPVQAPTQDQAAPAAEPAAQAPATSTTPQTTASPATQPVTAPAAQPQPVVATAANPSAELKIYDTTTQPISQLLAQAQQDGATLVVGPLLKENVEEVIKSNTPLNVLALNQPEKVESRANLCYFALSPEDEARDAARHIHQQGKQTPLLLVPRGALGDRVVSAFADEWLKLGGASVLQQRFGSTAELRAGVNGGGGIALSGTPVSTLPSAQNSILGSADEMPVSSGGSVDAAYILATPEQIAYIKPMIAMRNGSQSNVTLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGSNPSLMQQALSAVRNDYSLARLYAMGADAWSLANHFTQMRQTPGFELNGNTGDLTANQDCVINRKLSWLKYQQGKIVPAS
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: GRPE_BACCR
Sequence: MEERNEQVVEEVKEAQVEEAVTPENSEETVEEKSEAALLQEKVDELQAKLTETEGRTLRLQADFENYKRRVQMDKQAAEKYRAQSLVSDILPALDNFERAMQVEATDEQTKSLLQGMEMVHRQLLEALTKEGVEVIEAVGKQFDPNEHQAIMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_MYCS2
Sequence: MPDVTGDLAPLTPGARVLVTGAGITGRAVLGALAPLEVAATLCDDNADALAALAAKGVAVIAPGDAIASIGDYALVVTSPGFAPSAPVLAAAAAAGVPIWGDVELAWRLDAAGRYGPPRRWLVVTGTNGKTTTTSMLHDMLVAGGRRSVLCGNIGDPVLAVLDQPAELLAVELSSFQLHWAPSLRPEAGVVLNVAEDHLDWHGSMAAYARDKARVLDGRVAVVGLDDPVAAGLLPTAAATVRVGFRLGDPAAGELGVRDGKLIDRAFDDGVELADCADIGVAGPIGVLDALGAAALARAVGVAPGAIGAALASFQVGRHRAEVVGTVDGVVFIDDSKATNPHAAQASITAYDRVVWVAGGLLKGASVDELVRQVANRLAGAVLIGRDRQMVADALSRHAPDVPVVELVAGEDSGVLGTNESIESVGDHVTRVIEVGGRPVSDAVMSAVVSAARDLASPGDTVLLAPAGASFDQFSGYGQRGDAFAAAVRAAVG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTPA_ECOLI
Sequence: MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINYRNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSPILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDPLMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides as well as structurally related peptidomimetics such as aminocephalosporins into the cell.  Has a clear preference for dipeptides and tripeptides composed of L-amino acids, and discriminates dipeptides on the basis of the position of charges within the substrate.
What are the official names of this protein?
Dipeptide and tripeptide permease A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BRD2_CANLF
Sequence: MLQNVTPHSKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPQLLAVSAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEAKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLAKSSSESSSEESSSESSSEEDEEEDEEEEEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGVDEDDKGSRAPRPSQPKKSKKASGSGGGSAATLGPPGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKASEKTESSSTQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
What is the function of this protein?
Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling.  Regulates transcription of the CCND1 gene.  Plays a role in nucleosome assembly (By similarity).  May play a role in spermatogenesis or folliculogenesis (By similarity).
What are the official names of this protein?
Bromodomain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin and nucleosomes.
Protein: RR7_CEDDE
Sequence: MSRRSTAEKKTAKSDPIYHNRLVNMVVNRILKNGKKSLAYRILYRAIKNIQQKTEKNPLSVLRQAIRRVTPNVTVKARRVGGSTYRVPVEIRSTQGKVLAIRWLLGASRKRPGRNMDFKLSHELMDAARGNGNAIRKKEETHRMAXANXAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.