PharMolix/UniProtQA huggingface dataset:
Protein: LSRF_SALPB
Sequence: MADLDDIKDGKDFHTDKPQTNTLFALKGCGALDWGMQSRLARIFNPKTRKTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPPAINKPVVLRASGANSILTELSNEAVAVAMDDAVRLNSCAAAAQVYIGSEHEHQSIKNIIQLIDAGLRVGMPIMAVTGVGKDMARDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIAAGCPVPIVIAGGKKLLEREALEMCYQAIDQGASGVDMGRNIFQSEDPVAMIKAVHAVVHHNETAERAYELFLSEKG
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDUI_SALNS
Sequence: MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDRIIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFHMMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: TBX6L_CHICK
Sequence: MQVLPDIKAPCDALASPSLEPYPQSSITVTLEDMGLWMKFHQIGTEMIITKSGRRMFPQCKIKVSGLIPYAKYLMLVDFVPVDNFRYKWNKDQWEVAGKAEPQLPCRTYVHPDSPAPGSHWMKEPVSFQKLKLTNNTLDQHGHIILHSMHRYKPRFHIVQADDLFSVRWSIFQVFSFPETVFTSVTAYQNEQITKLKIDNNPFAKGFREHGKNTRREGRAKSQKPSPAKGQKRKLPEEKESGAEERDFEKDENVDVKEESNPIVVSSGYPFWISEQNSSHAFPAASPAPAEQREGPAREQQVPTPSYQTYRFHEAGDSQQLPSRDVAALNDFRGRCHPLDLATVPEHDSKQLPEGFTNLPP
What is the function of this protein?
May be involved in regulating somitogenesis.
What are the official names of this protein?
T-box-containing protein TBX6L.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSMD1_MOUSE
Sequence: MAGAGPTMLLREENGCCSRRQSSSSAGDSDGEQEDSPATRARQQLEALLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLSGGPYL
What is the function of this protein?
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
What are the official names of this protein?
N-alpha-acetyltransferase 38, NatC auxiliary subunit, LSM domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CXL10_RAT
Sequence: MNPSAAVVLCLVLLSLSGTQGIPLARTVRCTCIDFHEQPLRPRAIGKLEIIPASLSCPHVEIIATMKKNNEKRCLNPESEAIKSLLKAVSQRRSKRAP
What is the function of this protein?
Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity).  Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity).  Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization.  In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation (By similarity).  Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site.  This recruitment is an essential element for neuronal reorganization (By similarity) (PubMed:30257241, PubMed:30448292).
What are the official names of this protein?
C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Interferon-inducible protein 10, Protein Mob-1, Small-inducible cytokine B10.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PARC_STAAR
Sequence: MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDFSVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNSDLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERLSLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLFIPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKENDDLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKILQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DCL1_ASPTN
Sequence: MTHQNTETASLATTKGALEPLPPDKTAGLSTGAGHEISSDESEGSEEETGLHKDPSQRQRQQNATFQAFLSHHAETIVNSPVKPNQAQSELSISSLIGRNASGTGILNPREYQIELFERAKVQNTIAVLDTGSGKTLIAVLLLKHVIQTELIDRANGNPPRISFFLVDSVTLVYQQASVLRNNLDQNVAHFFGAMGVDLWNKQTWAEHFEKNMVIVCTAEILNQCLLNAYITMQQINLLVFDEAHHTKKDHPYARIIRDSYLRVPPSSRPRIFGMTASPVDTKGDVLEAARNLEALLDSKIATTSKLTILRQVVNRPNEEVWIYDKLQPTFTSDLYKLMESRFGDISHLEPMFRFARHATSELGTWCADRVWVSALADDVLPKVEGSIGGKRQSTGLGQLPKDVHRDITRIKEASELVESHPPNDPGAPEALSSKVRVLWKEISQCFGQETNTKCIVFTEKRYTAKVLFDLFTVLNVPGLRPGVLIGVRSSDRIGMNVTFRQQILTMVRFRTGEINCLFATAVAEEGLDIPDCNLVVRFDLYKTLIQYVQSRGRARHADSTYASMIEKDNADHESILVQVNDAEKIMQSFCQLLPEDRILHGNDDDTDAVLDREEWEEPYTLPSTAARLTHHSAITVLARYASSLQYENDTSAQVTYVVLPVNDAYVCEVILPEKSPIRGATGMPAMKKSTAKRYAAFEACRLLRKHRLLDEYLNSVYHRRLPAMRNARLAITSHRTNEYKILPKSSLWNKQIGVIPGKLYGTVISLKPLTPLAREHGSMILFTRDRLPQFPTFPIFLGEDVETIVLTVPVNMELQPSADELDYMTTFTLRIFRDVFRKTYDKEPEKLPYWLLPAISFPCNQEADPRDVVNWEILSSVHERDDIEYQADMPPEMLVDRFVYDHWDGRYRYFTLAVDENLQPSSPPPSHVARRRHMDTIMNYSISLSKNSRAKFLSRCNWNQPVLHAELVRLRRNLLDRMTDKERKLETRSVICIEPLKISAIPAAIAATCLAFPAIISRLDAYLIGLEACKKLGLEISLEYALEALTKDSDNTHEHRSQQVHMQRGMGKNYERLEFLGDCFLKMATSISLFNQHPDDNEFDYHVNRMCLICNRNLFNSAVKKELYQFIRSRGFSRDTWYPEGLTLLQGRDHSKKIGSESKHALAEKTIADVCEALIGAALLTPGPQHRFDMGVRAVSAVVDSNEHNAASWRDYISLYSIPKYQEQAPDGSEIDLCRRVEEKLGYHFRYPRLLHSAFTHPSYPSAWARVPCYQSLEFLGDALLDMVCVEDLFRRFPDRDPQWLTEHKMAMVSNKFLGALAVKLGLHTHLSYFSSALQSQITHYAEEAQAAASQSDVAVDYWTLTQDPPKVCLPDMVEAYLGAVFVDSNFRFEEVEVFFQQHIKPYFHDMAIYDTFANRHPTTFLHNKLTNEYGCLNYCLKAGEIPGADGDASTVLAAVIVHDTILTTGVASSGRYAKVKASENALTELLHIDRNEFRKRYQCDCVQENGEHGERDVGTPI
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: Y1097_GRABC
Sequence: MAGHSQFKNIMHRKGAQDARRAREFAKVIREITVSARSGLPDPASNPRLRAAISWAREVNMPKDTVDRAIKKATGAGQGDDYAEVRYEGYGPAGVAVIVEALTDNRNRTAADVRSAFSKYGGALGETNSVSFMFSRVGVIRFPASAGSADDMLEAAIEAGADNVESTAETHEITTSVEDFFAVRDVLESRFGAPEAAKLDWRPGTTVTLDQDKASSVLKLLDVLEDNDDVQAVYANFDIPDDVMQALSA
What are the official names of this protein?
Probable transcriptional regulatory protein GbCGDNIH1_1097.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3601_SHEB8
Sequence: MPSMDIVSEVNEVELRNAVDNTKRELATRFDFRGKTADVEYKDHVVTLTAEDDFQCQQLVDILRMQLSKRNVDPSSMEVDEKAIHSGKTFSLKVKFKEGIETLIAKKLVKLIKDSKLKVQASIQGEKVRVTGKKRDDLQAVMALARESELGQPFQFDNFKD
What are the official names of this protein?
UPF0234 protein Shew185_3601.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RNZ_RHOCS
Sequence: MFQLTFLGTGATVPSARRGLSALLVEHETDRFLVDCGEGTLRQIRQGGVGVRRLDRILLTHGHLDHILGLASLVGTLDLWDQADRLTLYGSEEALHIARVLLDQVVWPDDHPGLDVIYATLKPGRFCETGGVAVTAFPVCHHETQSFGFRFEETEHRPLDGARLDALGVPEGRERHELAHAGAVTLADGRTVRREDALGPAERGTSLAVVGDCGDADALVESVRGVDLLVIEATYRTADEATARSRSHLTVADACRLAQAAGVGRLVLTHQSDRYDPAEVEAEARARFEPVMVAKDFDRVEVRPAVRS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: MDM10_CRYNJ
Sequence: MIGFSAFILRNYYAAIGWNEDNLYSSLTRTSSALLDFQLPQSLILQLANSPTPIFFTSYALDALPQLNGSISYITTSMPLDEIGSGRATAFKNVIERFRVFPPPKRPQPKDEVWLGGKRIEGRDYLLYSRLHLPSLHLSGLATTRLTPTLQAHLAFLSQPAHPTSTRPTPPQTPPSHTRQPSEPSTPAPSPTPGNVFISLQHDTGRYCGEYTYSVQDGMVGLRTLYNFGWHGDEESEVDKKERREREGKRIDEEEMMEGGLKGRFSAGGEVYFSAKQRSFGISTGLRFTTVPPTLPLPLNAPVPSPPTTLTLLYNPLIGFLSSAYSAQVSPTVALATRFGVNVYSYESDLSVGGEWWIGRRRGKRGLTTDAEPQLDAESRDPVVTGIEENRELTEKMAQRASLRQVTLRDEIGEDVHAEKELYSPIPVMTDVNAGELAQQISPRLQPQQDLDDERDGVLKARLSGNWQFALLYEARIRNCLVSAGVLADLTGRQHPIRSIGLEVQYFS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: COBQ_BRADU
Sequence: MARALMIQGAGSDVGKSLIVAGLARAFTRRGLRVLPFKPQNMSNNAAVTVDGGEIGRAQALQALAAGVEPHTDMNPVLLKPETDVGAQVVVHGKRIATARAREYAAMKPSLMGAVLESFERLKARADLVLVEGAGSPAEVNLRKADIANMGFARKADVPVVLIGDIDRGGVIAQLVGIKTVIDPDDAAMIQGFVINKFRGDPTLFDDGYKLIEAKTAWRGFGVLPWFARAGELPAEDALGLSDARKPGQCKIACLALSRIANFDDLDPLKLEAAVDLVMVRPGEAIPGDVRLVIIPGSKSTRGDLAFLRAQGWDIDLLAHYRRGGHVLGLCGGYQMLGRSVADPDGIEGPAGDTPGLGLLDVQTVMSPQKTLTRVTAVHAATNQPIQAYEIHIGRTDGPDRARPFAKLNGEPEGAISSDGRVQGSYLHGLFTSDDFRKAFLTKLDIPAGDEPYHSRVESALDALADHIEKHLDVEGLLSLAR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: YS74_CAEEL
Sequence: MYRFLSGIKVVEIAGLAPVPHCGMMLADFGADVTVIDKKNPAIEQRLNRGKTMKQLDLKNPEDIKKVRDLCQTSDVLLDPYRPGTLEKMGLDPSTLWNNNKGLIICKISGYGQTGRMSQETGHDINYVALSGMLPTFSGVNATRPWPPANMLADFAGGGLSAAFGILSAIYARSHNGGKGCLLDCSMTEGVAYLSSFVQHYYDQPNLFTDKYALFSGECPIYRTYKTKDDKFVAVGAVEPKFYQNLFKLLNVDGRDLFVNPGKITEDLESRFLQKTRDKWANIFKGQECCVTPVLDIHEVGSYGQHVDRNSFTKTSSNWIANPSPRVWTQDELAALSSKK
What are the official names of this protein?
CaiB/baiF CoA-transferase family protein ZK892.4.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: TDRD7_HUMAN
Sequence: MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVVRIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPKATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRHVTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASALPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
What is the function of this protein?
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation.  Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens.  Also required during spermatogenesis.
What are the official names of this protein?
Tudor domain-containing protein 7, PCTAIRE2-binding protein, Tudor repeat associator with PCTAIRE-2, Trap.
What is the protein family that this protein belongs to?
Belongs to the TDRD7 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity).
Protein: RL14_CLOB8
Sequence: MIQQQTLLKVADNSGAKEIMCIRVLGGSKRKFGNIGDVIVASVKSATPGGVVKKGDVVKAVVVRSVKGVRRADGSYIKFDENAAVIIKDDKQPRGTRIFGPVARELRDKEFTKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RTF2_DICDI
Sequence: MGLDGGTIPTRCELVKTKKKEVKVFDKDQVDFGKWFLCALAQDTLSEPIVLDDLGNLFNKDNIIEALLNGSLETSKNFSHIRSLRSIYTVNFSPNPAHEKDSTVSPWLCPITKIEVGSSNYKFKFLKTCGHVFSEKAFKELKNDDSNNNNNNNNNNKKEIDSSKDNLSCFLCSKEYITNDLITINPSGEEFEQMKVTLQEKLANSKKKSSKKSDKKPDNKKRSLESNLASESSFTSNTLAQTNEEISKKMKSEAFSSIFKSNSNNDTTKTPNK
What is the function of this protein?
Replication termination factor which is a component of the elongating replisome.  Interacts with nascent DNA.
What are the official names of this protein?
Replication termination factor 2, RTF2, Replication termination factor 2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the rtf2 family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes at the replication fork.
Protein: ATPE_BUCA5
Sequence: MNFYLDVVSLTKTIFSGFVEKIRVSGSEGELGIYPGHAQLLSILKPGMVYIFHKKDKKEECIYISGGILEVQPSVVSILADVAIHAIDLDRSRILKTKKNAEESIKSNNTKINKDAILLQISKEIAKLRVLEVMDKFK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCSPA_METS5
Sequence: MDNHPWLPNISRIKDMLREIGVDDVEQLFQDVPRDLILRRELKVGYDSPLPEEDIRWRLNQVAERNLKLRYPPFLGAGAYPHSIPSVIRFILSRSEFYTAYTPYQPEVNQGLLQGLFEYQSLMAELLEMDVVNSSHYDWGGSLAEAVLMGYRINGKRKVVIPESINPLHEEVLRTWVSGRELEVVKIPVGKDGKIDLDFLSSLNSDEISSIYIQQPNFFGVVETELEYVTDWARKNNVVSIMGVSPLSLGLIKTPGELGFDIAVGDGQELGIPLNFGGPYSGILATRMDMKLVRQMPGRIVGMTQDSQGRRGFTLILQTREQFARREKATSNITTNEALIALANAVYLSLLGKEGIRELATEIYKRSHYALKRMEDEELGKRKWESDFFEEFTFVFRSDYDRIHSELLRRGIHGGLRLGPREALFCVTEVHTKRAIDDLVNAMKEVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RL18_STRMU
Sequence: MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNIFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CDD_HAEIE
Sequence: MQELIKRTLPQDDALNQAIVNELRSQNWAGFLNYSQVQQLCHNFELTPLKLAMHLLPLAASYSHTAISHFNVGAIAIGEQGDFYFGANQEFANSAIQQTIHAEQSAISHAWLRNERRISDMVVNYTPCGHCRQFMNELHGAEKISIHLPHSQNNPLHSYLPDAFGPKDLDIAAHLLADENHDLIADHQDDLINQAILAANQSHCPYSNSPHGIAILFKNGDMVTGRYAENAAFNPSLPALQTALNFAYLNDKKLSDIERIVMAEKALKLSHKTMAETLLSTLTSVELEYYSL
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: PSBL_THEVB
Sequence: MEPNPNRQPVELNRTSLYLGLLLILVLALLFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.  This subunit may make specific contacts with lipid(s) (PubMed:16355230).
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: UPPP_VIBVU
Sequence: MSYFEAFVLALIQGLTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVIYFRKEVITLFAALFASIFKGERSKEAKLAWMIVIATIPACIFGLVMKDVIEVYLRSAYVIATTTIIFGLLLWWVDKNASLLDDEYQAGWKKALFIGIAQALAMIPGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLVTSGEPVHVGFLLTGIVTSFISAYLCIHLFLKMISRMGMTPFVIYRLILGVGLFAYLLMA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDK_PROM2
Sequence: MTKERTFIAIKPDGVQRGYVAEIIGRFEKKGFKLVGLKQLIPSKDLAQNHYGVHRERPFFGDLVDFISSGPVVAMVWEGEGVILSARKLIGATKPLEAEPGTIRGDLAIDIGRNIIHGSDGEDTAKFEIDLWFNEEELCEWETSDAKWRSEN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CED8_CAEBR
Sequence: MYLKKHESKLLLIPKNEDKEDAGIIAVLTDRVPSVLIVRWFDLFCFGFAMCSYVLDFFSDIGIAIFHFWAGRHLSGALVLTFALIPSVIINIISMVWMLDDEMHWKRRAHPRRTGTFELNQKRFISLGKMITLCIFQMGPLFWYYKALYYGWMFTKNKKDDTDKEKRKFFMKMVEAERDATLLRFFEAFLESAPQLIIQGSIAANYFQNYYISGKYPYWLYFQAASLTLSIISISWSVVVQNRSLRMTRDDKVNIWPHEAVLQFCWRFLTILARIITLVAFVLLFGIYVVFLIFGHLIVTLVHVIFLQALHIEACTHIEKLLLLINAMIHLFTPFNMAEGNTRYRYLVAYTVEFIEMMIIFLLLPTPLDAFPLIEKIRIGVPATFFIGIFIMLIYYKFFHPNRRQDLEAPNVERNEKLVVSELNGIPSAAIEKAEHIEEIEEHSVPTTSESLLEEDECHN
What is the function of this protein?
Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling.  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.  Regulates apoptosis kinetics during embryonic development.  Not required for engulfment of germ cell corpses.
What are the official names of this protein?
Cell death abnormality protein 8.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIG_YERP3
Sequence: MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKVLDVGCGGGILAESMAREGAQVTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTINRNTKSWLMAVVGAEYLLKMVPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRDSE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.