PharMolix/UniProtQA huggingface dataset:
Protein: EXU2_DROPS
Sequence: MVSAISEDSASATASGQCEVVKEELPAGNYILVAVEIDTTGRRLIDEIVQLAGYTSKGNFQQYIMPYMNLNQAARQRHQIRVISIGFYRMLKSMQTYKIIKSKSEVAALMDFLNWLETLLAKQPNKEGIVMLYHDDRKFIPYMILEALKKYSLIDRFNRSVKAFANTCPMAKTFLGKHGIKNCGLRKLSMLLAKSKDGNSTKEDEHENPEGNSSITDNSGHKNQKQGAFEGSANVRAKMVYEMALQLIESESTESPESFESPESSESSEAEVKLLNAVRPFSQLLSSTILELKDQNHSLGRQNSFRPVFLNYFRTTLNYRVRAVKYRIGLAEHGFTLKSLKAIWSDKRKPGLELVLTAIDSLKTEETAELLDLLDSYYDPSKTTIKPRCKRSGNGTRRRNRAKGAASSKNGAIGAGGDNSVPDSATKPGGRPRRKRNNIRNNILGPQNTEKGSPKAEMKTSTPKSMSIKPPSEFADI
What is the function of this protein?
Ensures the proper localization of the mRNA of the bicoid gene to the anterior regions of the oocyte thus playing a fundamental role in the establishment of the polarity of the oocyte.  May bind the bcd mRNA (By similarity).
What are the official names of this protein?
Maternal protein exuperantia-2.
Protein: ILVC_PROM0
Sequence: MTQLFYDTDADLSLLNNKTIAIIGYGSQGHAHALNLKDSGMDVIVGLYKGSKSESKAISDGLKVFSVSEACEKADWIMILLPDEFQKDVYLKEIEPNLKEGKILSFAHGFNIRFGLIKPPSFVDVVMIAPKGPGHTVRWEYQNGQGVPALFAVEQDSSGSARSLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKSGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLSQMRDSISNTAEYGDYVSGKRLINSDTKKEMQKILKDIQDGTFAKNFVEECDKDKPLMTKLREENSKHEIEKVGKSLRSMFSWLK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PETD_PROMM
Sequence: MHILKKPDFSDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTFACLVGLAVLDPAMLGDKADPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLVPLGLMLIPFIESVNKYQNPFRRPIAMAFFLFGTVITIYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL22_PSEE4
Sequence: MEVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSKKAAEIMKKVLESAVANAEHNEGADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: OTRF1_STAAW
Sequence: MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWNKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
What are the official names of this protein?
Putative O-acetyltransferase MW0856.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4KF_SINFN
Sequence: MFVHGVNNRKEDAGFDNDVARKKEFLKTLLAAPLGLDPAKVHISFPYWGGDGVKFLWNQVSLPGGGYETLALGAQKNEIDLWLHEVQQSFGAKSVILGKVSRDQSFADAVDLIWDAAAATANSPENIEKIAAAYQASQRYIEKYPAPAWALKAEPLSNEEFLDALLRGIAELPADEKKLETFGLSGWLASTKEALARLGSAPADATTAGLLALGRKSAHQKASRFLGDVFVYLKNRGTAAAPGPIVRAVLQAFRNADAARQEGDDKLIIVGHSLGGVITYDILSYFAPDLKVDYLATIGSQVGLFDEMALYSRPLPPGMPTDPKNDRIAANPNVGKWLNVFDTNDVFSFSAEGIYKSVKDFQYDTGYGGFGAHGGRNRHIDEHRFRIHGSESRSDRRRDACPLDRLRRVSEPCGCGIWKPAVSHVAADLRGRRR
What are the official names of this protein?
Uncharacterized protein y4kF.
Protein: BDNF_ANISC
Sequence: GQGSLAYPGLRTQGNLETLGGPNDATRGLTSLADTFEHVIEELLDEQQVIQPSKENKDADLYSSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQXFYETKCSSKGYAKEGCRGIDKRYWNSQCRTTQSYVRALT
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2M_HALGR
Sequence: MKPPILIIIMSTVMSGTMIVLTSSHWLLIWIGFEMNMLAIIPILMKNHTPRATEASTKYFLTQATASMLLMMGIIINLMFSGEWSISKIPNPIASGLVTIALTMKLGMAPFHFWVPEVTQGISLSSGMILLTWQKIAPLSILYQISPSINPKLLITMAIASVLIGGWGGLNQTQLRKILAYSSIAHMGWMAVILTYNPTLMILNLTIYITMTLSTFMLFMHNSSTTTLSLSNTWNKLPLMTSLILVLMMSLGGLPPLSGFAPKWMIIQELTKNDMIILPTFMAITALLNLYFYMRLSYTTALTMFPSVNNMKMKWQFESAKKIILLPPLIIISTMLLPMTPMMSILE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KDSB_ALISL
Sequence: MSFTVIIPARYQSTRLPGKPLADICGKPMIQWVYEQASKAGADRVIIATDDSRIEAVVKGFGGDVCMTSPNHESGTERLAEVIDKCGIASNEIVVNVQGDEPLIPPSIIRQVAKNLADSIAPMATLAVTIDEEEDVFNPNAVKVVTDAEGYALYFSRAAIPWDRDAFAKGEALTANPLLRHIGIYAYRAGFINTYINWQPSVLEKIECLEQLRVLWYGEKIHVAVAKEAPAAGVDTQEDLDKVRAILAL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GERPE_BACSU
Sequence: MLKRISRIRLVKFNSLGIASVFQVGDTNEIDMSVKVFAVQRSLSTFYHNEGSFNKKEYQIFQQQAVKPLPETGVQSAFCHEVPAIYVRSIKIQGVSASSVLHAGSASLIRGDARLKHIRQIQSPRSQSPAKNI
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPE.
Protein: EFTU_PSECP
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISKVLYDKYPDLNEKRDFASIDSAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLARQVGVPYLLVALNKSDMVDDEELLDLVEMEVRELLSSQGFDGDEAPVVRVSGLKALEGDPVWVKSVEDLMAAVDESVPDPVRDRDKPFLMPIEDVFTITGRGTVVTGRAERGTLAINSEVEIVGIRPVQKTTVTGIEMFHKQLDEAWAGENCGLLLRGLKRDDVERGQVVVKPGSITPHTDFEANVYILSKDEGGRHNPFYSNYRPQFYFRTTDVTGVITLPEGTEMVMPGDNTEMTVALIQPIAMEEGLGFAIREGGRTVGSGRVTKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAB_AMYME
Sequence: MIPAQFTYRRVSSVDEALAAVAEHGD
What are the official names of this protein?
Aldehyde dehydrogenase beta chain, ALDH.
Protein: Y1121_PYRAB
Sequence: MGVIINESKSVKWEGKVEIADNFIKRAFGFMLRNPGHALIFILPFETRFNATIHGFFMLKSIDVIFLDSEKTVVDVTTLRPWRIYVPKKAAKYVIEGPVGLRKVLKVEVGDKVEWIT
What are the official names of this protein?
UPF0127 protein PYRAB11210.
What is the protein family that this protein belongs to?
Belongs to the UPF0127 family.
Protein: EFP_NEIMF
Sequence: MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKFDVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTEIQVMSYIENGDKIEIDTRTGEFRKRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_RALPJ
Sequence: MAEHQVPRPQKPPRRDVHGVLLLDKPIGWSSNDALIRAKRLLWAKKAGHTGTLDPLATGLLPLCFGEATKFSQDLLDADKTYETVVRLGIRTSTADAEGEVLSERPVSVTPEQLQAAIARFVGEIDQVPPMHSALKKDGKPLYEYARAGQTVERAARRVTIYAIDVLATDLQSAEPTVTLRVSCSKGTYIRTLGEDIGEALGCGGHLVALRRTQVGNLTLDGAVTLEALDAAAEDARGALLAPVDALLQTLPRVELDAQESRRFLHGQRLPLQLALPNADQVRVYGVRDAIAADATASLLGVAAWQGGVLRPERLVHL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: TORD_SHESM
Sequence: MSNVDINHARALVYQLLSSLFAREIDEQRLKQLTSEQAQQFWTQLGYAPEFSAPVASIQKVLNDLTSDEALLELAADYCGLFLVGTKYSASPYASLYLSPEEEPLLFGQQHQQMSEFLHQSKLQVQSHFPEPADHLAVILAYMGHLACHSEDAAQLSFLNTCIDSWLAKFVAKVIECDSQHSNGFYSALATLTLAWVQQDKQQLEQAIH
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_SYMTH
Sequence: MGFRIAVDAMGSDAAPAPEVSGTIQAAREWPDLRFVLLGDDSRIRAEAEKAGGLPGNVEVVHTTQVITPDEEPTKAVRSKKDAPLTVAARLVKEGQADALLSAGSTGALVVVGTLGIGRMKGIDRPALGTIMPTVKQPVFMLDVGATPDARPEWLVQFALMGDIYAREILGLSRPRVALLSNGTEAEKGNAVVKATYPLLQELPSIHFIGNIEARDVPFGGADVVVADGFPGNVLLKTYEGVAMALFQSLKEALTGSPLTAVGAALAKPGLKKMAKRFDYTEYGGALLLGLKAPVVKCHGSSNARAIYSGLRVMKLALEGRVIDRLAEAIAQLPAKNPKEEGDPPA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ASTE_SHEON
Sequence: MLQALLDSKDFLALTLANPQTLGDEFSFTLGEHTRVNVWDTGVIVFEPAQPQGKDVILSCGVHGNETAPIELCNTLIKQLLQQKIIAKQRTLFLIGNPLAINNGTRIIDENMNRLFSGEHSNPPGLVNPERLRAKKLETYVDRFFKAAAAGRQRIHYDLHTAMRASKHEKFAIYPYRPGRAYSAEQIMFLAASGVDTVLFHHEPTTTFSYFSSEQYGADAFTIELGKVYPMGQNDMTRFIAAQEMFTRLITDKPLQLESFSTDKVNLYQVCRVINKHFDDFEFTFATDVENFRAFPKGFVLAREGGQEIKVEQEVESIVFPNAKVPIGNRTVICLIPSVAPDVR
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: NGN3_MOUSE
Sequence: MAPHPLDALTIQVSPETQQPFPGASDHEVLSSNSTPPSPTLIPRDCSEAEVGDCRGTSRKLRARRGGRNRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSFYGPEPPVPCGELGSPGGGSNGDWGSIYSPVSQAGNLSPTASLEEFPGLQVPSSPSYLLPGALVFSDFL
What is the function of this protein?
Acts as a transcriptional regulator.  Together with NKX2-2, initiates transcriptional activation of NEUROD1.  Involved in neurogenesis.  Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
What are the official names of this protein?
Neurogenin-3, NGN-3, Helix-loop-helix protein mATH-4B, mATH4B, Protein atonal homolog 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVD_METMA
Sequence: MRSAIIKEGPERAANRSLLKATGVTDAEMKRPFIAVVNSWNDIIPGHIHLNKLAEAVKAGIRNAGGVPFEFHTIGVCDGIAMGHEGMKYSLPSREVIEDTIELMVRAHQFDGMVLIPTCDKIVPGHLMAAGRLDIPAIVVTGGPMLPGYVDDKYTDLISVFEGVGAFRAGKLSEAELERLENLSCAGAGSCAGMFTANTMACMTEALGLSLPGCATAHAVDAKKVRIAKESGERIVELVKQNITPRKIVTYKSFENAIMVDMAVGGSTNTTLHLPALAHEFGLELPLEAFDELSRKTPHLISLRPGGPNFMLHFDRAGGVEAVMQRLSSKLHLDQLTVNGKTIGENISELEIINPKLNEEIIKTLENPIHAEGGIAVLKGSLAPDGSVVKQAAVDPKMRVHTGPAKVYDCEEDAMKSILAGEVKPGDIVVIRYEGPKGGPGMREMLAATAAIAGMGLLESVALVTDGRFSGGTRGPCIGHVSPEASEGGPIGLVKDGDLIEINIPERILNLKVSEEELEKRRSVFNPPEKKVTGYLARYQRAVHSANTGGIVD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: COQ7_BORA1
Sequence: MNYASPRHAGPLDALLIEVDRALQVLSRSAVAGRAYPAHAAEAPLADTEKRHAAGLMRVNHVGEICAQALYRGQAVACRDAGTRELLREAAAEEVDHLVWCDRRLKELDSRPSLLNPLWYAGSFALGVAASVAGVPRNLGFMAETERQVEAHLDEHLRTLPAADERSREIVRQMKDDEAGHRESAERAGGIPLPAPVRGIMRAMSKVMTGTAYRL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1069_AGRVS
Sequence: MAFSTLKSDRERGFLDGHFLIAMPGMADGNFTRSVVYVCAHTTAGAMGFIINRTQPVKFADILLHLDLIDQNDAIMLPDHARNFPIQCGGPVETGRGFVLHSDDYLSDSSIPVSDDISLTATLDIVRAISDGRGPARATMLLGYAGWGPGQLEAEIANNGWLNCPASEDLIFDPVLDNKYDRALALIGISPATLSAEAGHA
What are the official names of this protein?
UPF0301 protein Avi_1069.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MIB_DROME
Sequence: MSCAATLSSAKDSTNANASGGGGGGGGGGAPTNSNTNTNTNTQSTAVGVVVSSAAGTGVGVGGGGGGGGSLPGGTTSSSSASAAGGVAAGGGGNSAAALVRRFSMEGVGARVIRGPDWKWNKQDGGEGHVGTVRNFESAEEVVVVWDNGTAANYRCAGAYDLRILDSAPTGVKHEGTMCDTCRQQPIFGIRWKCAECINYDLCSICYHGDKHHLRHRFYRITTPGGERTMLEPRRKSKKVLARGIFPGARVVRGVDWQWEDQDGGVGRRGKVNEIQDWSSASPRSAAYVIWDNGSKNLYRVGFEGMADLKVVNDAKGSNVYRDHLPLLGENGPGKGPHGFQIGDKVTVDLDLEIVQSLQHGHGGWTDGMFECLSNAGMVVGIDEDHDIVVAYNSGNRWTFNPAVLTKVSSPTTAPPEFQVGDIVKICSDVESIKILQRGHGEWADAMQLTLGKIGRVQQVYHDNDLKVEVGNTSWTYNPLAVCKVASSTASDGSCAPVIPSSERLSAILKKLFEPNVSGDATEEFVKAAANGFAARCEEYLAGAAQPSTSSASPSSGPDVNVNGVFAGHTALQAASQNGHIEVIQVLLRHAVDVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQDSEGDTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVEEKKDDGYTALHLAALNNHVEIAELLVHMGKANMDRQNVNLQTALHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPLHEALRHHTLSQLKQLQDVEGFGKLLMGLRNANNKKASASIACFLAANGADLTLKNRKQQTPLDLCPDPNLCKTLVKCYNERKTDDSELPGNVAGTSSSARARAASGSLNQSSSVNMPLSSLAASSTFPAASSSSIFALNGIANEMSQSLHEDPPKSSASLDECLVCSDAKRDTVFKPCGHVSCCETCAPRVKKCLICRETVSSREKIDECLVCSDRRAAVFFRPCGHMVACEHCSALMKKCVLCRTQIDEILSFSLCCGGSGRPEKVSVAAGAMATVGLPLPDDRFMEAAAAAACANASGHSVAMNNTVVTPVAGSSNQLNSQNNLLAAAAASSNVSNLSAAGNAMVAPSNVNNFQMDDVQKLKQQLQDIKEQTMCPVCFDRIKNMVFLCGHGTCQMCGDQIEGCPICRKTVEKRILLF
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta (Dl) and Serrate (Ser) receptors, which act as ligands of Notch proteins.  Positively regulates the Notch signaling by ubiquitinating the intracellular domain of Dl and Ser, leading to endocytosis of Dl and Ser receptors.  Regulates a subset of Notch signaling events, including wing margin specification, leg segmentation and vein determination, that are distinct from those events requiring neuralize (neur) activity.  Also modulates lateral inhibition, a neur- and Dl-dependent signaling event, suggesting a distinct but partially complementary function with neur.
What are the official names of this protein?
E3 ubiquitin-protein ligase mind-bomb, Mind bomb homolog, D-mib, RING-type E3 ubiquitin transferase mind-bomb.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes at the apical cortex of cells.
Protein: RLMN_DEIDV
Sequence: MEFLLDLHPDAYPLEGFRRRQLLEWVFVQGVGTFDAMTNLPAEARAELARSYHLNPFREIETVRSADGSVKYLFTLTDGRQMEAVYMPYLDRKTICVSTMVGCPARCAFCATGAMGFGRNLTPGEIVAQVLAVAGGEGIGPREIRNLVFMGMGEAMLNYENTMQAARILLHPQALGMSKRRVTLSTVGIAKGIRQLAAEDDLGIKLAISLHAPDEDTRQRIIPTGAANSIAEIMAAARDYQAVTGRRITLEYTMLRGINDHLWQAELLADVLQGLVSHVNLIPMNPWDGSGFESSTEDQIQAFYDTLEARGVDVSVRRSRGKDAGAACGQLALKRPGAVTGAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_PSEPW
Sequence: MTKSELIERIVTHQGLLSSKDVELAIKTMLEQMSQCLATGDRIEIRGFGSFSLHYRAPRVGRNPKTGQSVELEGKFVPHFKPGKELRDRVNEEEHEHP
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: BCLA3_HUMAN
Sequence: MARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKVKNVHTDGFQKPTHFIKSNFRKCIEKPYMNYTTQRKDIITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPNYKSGLVQKSLYIQAKYQRLRFTGPRGFITHKFRERLMRKKKEYTDVATGI
What are the official names of this protein?
BCLAF1 and THRAP3 family member 3.
What is the protein family that this protein belongs to?
Belongs to the BCLAF1/THRAP3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMM_SACD2
Sequence: MILICLCRQGFEKEVAAEITDCAAYAGIAGYVKTNADTGYVEFVLPDLDSATALFEAIRFDDLVFVRHWFVTPAIASDLPKEDRASPLMASAQALPPLAKLEPITLDTNDGKALVALTRGVTNHMRTVFKKAGAFNAKSDWVGQVLFFSGEQACIGYFPQSNGSLWVGGIPRLRAPKDAPSRATLKLEEAWHQFIPREQWDQRIAPSMRAVDLGAAPGGWTWQLVNKSMFVEAVDNGPMAENIMASGQVTHRMEDAFRFAPERAVHWLVSDIADKPARVAELITRWAENKWFKEAVFNLKLPMKKRYIELQLCSEIITLALDNAGIEYTLKFKQLYHDREEVTGHLVLF
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS1_BRANA
Sequence: MASSMLSSAAVVTSPAQATMVAPFTGLKSSSAFPVTRKANNDITSIVSNGGRVSCMKVWPPVGKKKFETLSYLPDLTEVELGKEVDYLLRNKWIPCVEFELEHGFVYREHGSTPGYYDGRYWTMWKLPLFGCTDSAQVLKEVQECKTEYPNAFIRIIGFDNNRQVQCISFIAYKPPSFTGA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGR_STRCO
Sequence: MSHAQEHEQPAGPALPQTRTARHRRIVDILNRQAVRSQSQLAKLLADDGLTVTQATLSRDLDELNAVKIRNTDGDLIYAVPSEGGFRTPRAPLGESAKEERMRRLSAELLISAEASANLVVLRTPPGAAQFLASAIDQAELHDILGTIAGDDTLMLISREPTGGQALADHLLRLAQNGG
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT_ORYLA
Sequence: MDPCDCSKTGKCNCGGSCTCTNCSCTSCKKSCCACCPSGCTKCASGCVCKGKTCDTTCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.