PharMolix/UniProtQA huggingface dataset:
Protein: VATC_DESSY
Sequence: MEAVTGILNTTIAVVFTWVGYKTARIIWKYTPYSYPNARIKAMEAKLLTEQKFNELAESRTLQNFVVNLEDTDYKDYLADVSSYTVEEVEKALERALAGTYELMFKILPKRSKGFFELLLEGWDVRNIANVVKAKLANEPASDYVVELGTMLPKVKAMAEAKTLEEILVILEGTPYEEVYQKLLLGEIDVTRFETELYRMHYGKLLSYALSRKDDERIILEEFVRLSIDRVNILTALRAKKAGLSAEEIKPMLIPGGTVKLDPLLHVDSFDMALAELDSTKYGQVIRDVREEIEKDLSVLEKALNDHIIERISELERFYPLSIATPLSYVLRREREIRKLRAIAKLIENGVEPERIKELAGEVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: PANB_SULIN
Sequence: MKKVTIRDFIKKKSTKEKITMLTAYDYPTAKIISNTGLDSILVGDSLGMVVLGYPNTLNVTMRDMISHTRAVARANPPQLIVADMPFLSYEIDTKSAVKNAGLLVKAGSDAIKLEGGEEMKDTVKAIVKAGIPVMGHIGLTPQRFLRLGGFRTIGKTKQEEDQLIKDSLELEDAGVFSLVIENTYVDIAKRITEKLNIPTICIGAGPYCDGQVLVINDLLGLSEFTPYFAKSYVNLKEIISNAINQYIIDVKNNKFPEKQHYKERES
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD2_PYRAE
Sequence: MNVADLLASSRHCVVFTGAGISAESGVPTFRGPGGLWERYKPEELATPEAFARDPALVWRWYKWRQEVIYNARPSPGHYAIAELEAMGVVRGVITQNVDGLHQRAGSRLVVELHGSIWRARCVKCGSVYILDKPVEEVPPLCRKCGGLLRPDVVWFGEPLPQEAWRAAVELASVSDVLLVVGTSGVVYPAAYIPRIAKEAGARVVEINVEPSAITPIADVFIQGRAGEVLPRLVEEVKRRLRTRQALTP
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.  Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
What are the official names of this protein?
NAD-dependent protein deacylase 2, Regulatory protein SIR2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_ECOHS
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAIAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: C71D7_SOLCH
Sequence: MQLVSIFLFISFLFLLRKWKKYLNNSQTKKLPPGPWKLPFIGGMHHLAGGLPHRVLRDLAEKYGPLMHLQLGEVSAVVVTSPEMAKQVLKTHDIAFASRPKLLAMDIICYNRRDIAFSPYGDYWRQMRKICIMEVLSAKSVRSFSSIRHDEVVRLIDSIQPCFTSGELVNFTERIIWFTSSMTCRSAFGQVLKEQEVFIKLIREVISLAEGFDVADIFPSYKFLHGFGGAKQKLLNAHRKVDSIVEDVIKEHKKNLATRKSDDAIGGEDLVDALVRLMNDKSLQFPINNDNIKAVIIDLFAAGTETSSTTTVWAMAEMLKNPSVFAKAQAKVREAFRDKVTFDENDVEELKYLKLVIKETMRLHAPVPLLVPRECREETEINGYTIPVKTKVMVNVWALGRDPKYWDDAESFKPERFEQCSIDFIGNNFEYLPFGGGRRICPGISFGLANVYLPLAQLLYHFDWKLPTGMEPKDLDLTESAGITAARKGDLYLIATPHQP
What are the official names of this protein?
Cytochrome P450 71D7.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS17_GRABC
Sequence: MPRRVLTGRVTSDKMDKTVTVLVDRRIIHPLYKKFIRKSKKYAAHDEANECREGDIVRIVECPPISKRKTWEVVWRNGHVLSTAHKEAIDAAATQIAHAEASGEAAAAAAEHQGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: EX7S_SYNFM
Sequence: MAKKKSDQFEEALKKLQDIVEKLERGDMPLEEAMEAFSEGIRLARVCHGKLEEAERKVRILLKEQEGDWTTSPFEPASGEPPGG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_BDEBA
Sequence: MLSPKRVKWRKQFVGRATGFAVRGANLDFGDYGLQAVEEGRLTARQLEAGRIAISRSVKRGGKIWCRVFPNIPVTKKPAETRMGSGKGNPELWVARVLPGKVLFEMNGVTREQAKEAFERAAHKLPFKTRFLVRE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RYH1_SCHPO
Sequence: MSENYSFSLRKFKLVFLGEQSVGKTSLITRFMYDQFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIIVYDITNHNSFVNTEKWIEDVRAERGDDVIIVLVGNKTDLADKRQVTQEEGEKKAKELKIMHMETSAKAGHNVKLLFRKIAQMLPGMENVETQSTQMIDVSIQPNENESSCNC
What is the function of this protein?
Has a role in retrograde traffricking of proteins from the endosome to the Golgi.  Involved in protein transport to the plasma membrane.  Involved in the secretory pathway where it has a role in acid phosphatase secretion.  Required also in normal glycosylation trafficking pathways.
What are the official names of this protein?
GTP-binding protein ryh1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Nucleus. Cytoplasm, cytosol.
Protein: ORN_SODGM
Sequence: MPVNDNNLIWIDLEMTGLDPERDRIIEIATLVTDANLAILAEGPVLAIYQSDAQLALMNDWNVRTHTASGLVDRVRQSALDEEAAVAQTLAFLADWVPAGKSPICGNSIGQDRRFLFRYMPALEAYFHYRYLDVSTLKELARRWKPEILSGLKKNNTHQALDDIRESVAELAYYREHFIRL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBD40_ARATH
Sequence: MDRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSESEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPEDIRMWVVVAVSRYIRELKIYSSHYGEKQNILPSSLYTCKSLVILKLDGGVLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKLTVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSITSVKRLAISSEVGYGEGFIFNHLEELTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTCELNFS
What are the official names of this protein?
FBD-associated F-box protein At4g10400.
Protein: RHAA_SHIBS
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWGEWAKANQLGLDFNPSCFSHPLSADGFTLSHPDDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISKKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDCDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKEILSQRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_ECOLI
Sequence: MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKENAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEEQTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: FTSH1_PETMO
Sequence: MPENKNDKENKNDKENKNTKEEKKKVKFSNIIWVYIIFAVFFIGALISLNWENNPIISYSEMLSLINDGQVESMKINQNGNVEILSKDGTTYESFSPALVIDKQYVNSLIQKGIKVEYVESVGTKWWFGLLINIIPIVVMVLFFFWLYRSASAGARSSMNFGKSGAKKYEPIGEKVTFKDVAGIDEVLDEIEDIVKFLKNPQEFQELGARMPKGTLLVGPPGTGKTLTARAIAGEADVPFYYASGSDFVELFVGVGASRVRDLFKTAKENAPAIIFIDELDAVGRQRGAGLGGGNDEREQTLNALLVELDGFDTSTGVVVMAATNRPDVLDKALLRPGRFDKKIMVGPPDVKGREEILKIHTRKKKIAPDVDLKLLAKRTPGFVGADLENLVNEAALIASRKKKNQVEMSDFEEAIDRVLTGPSKKYRIISDKEKKILSYHELGHAVLAYLLPNTDPVYKITIIPRGAGSLGSTLQIPEKDKYLIKKSEILDRIVVALGGRASEKLVFNFATTGAKDDLRKATDYAKSMIYRLGMSKRMGPVYWEGEEEEIFLGSELTKQRNYSEETAKELDVEVKKIINSMYDKALELLKQNRERLDLLASYIFKNETIYGEEFKKLMSKDLEELKEYIGGEKEINEFLKIDVVNHVNYQPV
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: MACB_BURCH
Sequence: MRQPLLKLAAVTRRFPAGDKDVVVLNNVNLSIGAGEIVAIVGASGSGKSTLMNILGCLDHPSEGTYTVGGRDTHMLDSDELAQLRREHFGFVFQRYHLLPHVDAVANLEMPAIYAGTPRADRHARARELLARLGLADRAHHRPGQLSGGQQQRVSIARALMNGGQVILADEPTGALDTKSGQDVIRILHELNALGHTIVIVTHDKAVARHARRIIEISDGEIVADRPNRHYAEAFAEVGVGAAATTETAADTRSAPASGDAPPPANNDTAADPAPRARRFAAGTGRFAEACRMAWIALVSHRLRTLLTMLGIIIGITSVVSIVAVGEGAKRYMLEEIGSIGTNTISLYPGSDWGDSRADTIQTLVPADVAALAEQPYVDSATPETSRTLLLRYRNVDVHALVSGVGDSYFQTRGMRFALGVPFDDDAVRRQAQVAVIDQNTRRKLFGATRNPVGEAILVDNVPCVVIGVTADKKSAFGSVKSLNVWVPYTTASGRLFGQRYLDSITVRVRDGQPSAAAEKSLEKLMIQRHGRKDFFTYNMDSVVKTVEKTGQSLTLLLSLIAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARQSDILQQFLVEAVLVCLLGGTIGIALSFGLGALFSVFVAQWKMVFSAGAIVTAFVCSTLTGVIFGFMPARNASRLDPIDALARD
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URED_RHILO
Sequence: MDTIEYTEFSPPLAQRAAGLAQLGCASADGRTRLRRLYQDGSAKIRLPAVLADPLEAVLINTAGGLTGGDRIGWDVDVGTEASASITTQACEKVYRAASDQAEVRVKLTVGENGRIAWLPQETIVFDRAAFARTLDVELAAGAEALVLEATVFGRLAMGERASQGTFRDRWRVRQDGFLIHAEDFRIGPDITGALARPAAAGGVIAVATLLLVSPRAEALLDPVREIVGHQGGASVWSVKASGKLLARLYAGDGYQLRQRLVPLVGLLNGRAGLPKLWSL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TE2IP_HUMAN
Sequence: MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPGAVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK
What is the function of this protein?
Acts both as a regulator of telomere function and as a transcription regulator.  Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome).  In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair.  Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.  Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2.  Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression.  When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes.
What are the official names of this protein?
Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric protein 1, Dopamine receptor-interacting protein 5, Repressor/activator protein 1 homolog, RAP1 homolog, hRap1.
What is the protein family that this protein belongs to?
Belongs to the RAP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Chromosome, telomere. Note=Associates with chromosomes, both at telomeres and in extratelomeric sites. Also exists as a cytoplasmic form, where it associates with the IKK complex.
Protein: DIOXL_SCHPO
Sequence: MASSRLLDWMSRMRSVPQLERLIPALYLAHGSPFLMLPQSSDDEVFSNDSKLGGLHYQFLEQLGPFLLEKFRPKGIIVFSAHYESRGSVEVYSRDDENPLFYDYYGFPDYLYQIKFHSKGSKRIADQIISALKEYQIPAKTVSGDRGLDHGVFVPFKIMFPDGLNIPLIEVSMHTLDPMQLYKVGQALQSLRKEYLIVSGGLNIHTFEDLSAFNEDTAADGYKEFQLDILKAIETDKQNDRLNKLLGLQLHPYFRKAHPREEHFVPLYVAAGLGSSGKSKVVCDLYGAVSAFFGIDE
What is the function of this protein?
May be involved in the metabolism of aromatic compounds.
What are the official names of this protein?
4,5-DOPA dioxygenase extradiol-like protein.
What is the protein family that this protein belongs to?
Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YCHE_ECOLI
Sequence: MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALFALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN
What are the official names of this protein?
UPF0056 membrane protein YhcE.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VSP1_MACLB
Sequence: MVLIRVLANLLVLHLSYAQKSSELVIGGDECNINEHPFLALMYNSTSMKFHCSGTLLNEEWVLTAAHCDMENMQIYLGVHDKKNPNKDQQTRVPKEMFFCLSNKSYTPWDKDIMLIRLNSPVTYSTHIAPFSLPSSPPTVGSVCRIMGWGAITSPNETYPDVPHCANIEIYDYSVCRKAYGGLPEKSRTLCAGVLQGGIDTCLADSGGPLICNGQFQGIVAWGRHPCAQPQLPAFYTKVFDYSDWIQSIIAGNTAATCPS
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Serine protease VLSP-1, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CTRB_ASPFU
Sequence: MHQLSTSICLCFVISSPYVYLVSIACVLWTSIPFTSGMMDHSAMHHSGMDMDHGHGDMDMGGQCNMNMLFTWSTKDLCIVFSQWHITGPFSLLMSLIVIVLLTAGYEGVRQATRKYEAAQAQRLNVFSTTTATIARLKPSLTNGVQGNEFADESATTNVPSSQTPNESSPLVAGRDNRRAVEQRGKIILAALYAVQVFYSFFIMLLFMTYNGFVMLAVAVGAFAGYLVFGDNQSAAKTVACH
What is the function of this protein?
Transporter that is probably involved in the transport of copper, even if it does not act as a major copper transporter.
What are the official names of this protein?
Copper transport protein B.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
Protein: EFTU_ALCBS
Sequence: MAKEKFERNKPHVNVGTIGHVDHGKTTLTAALTRVCAEVWGGNAVAFDGIDNAPEERERGITIATSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIVVFLNKADMVDDEELLELVEMEVRELLSDYDFPGDDTPIIKGSALKALEGDTSDIGMPAVQKLVETLDEYIPEPERAVDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGIHDTTKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDEVERGQVLAKPGSINPHTKFVAEVYVLSKDEGGRHTPFFNGYRPQFYFRTTDVTGACTLPEGTEMVMPGDNVQMDVELIAPIAMEDGLRFAIREGGRTVGAGVVAKITE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QPCT_GLOBL
Sequence: MARERRDSKAATFFCLAWALCLALPGFPQHVSGREDRVDWTQEKYSHRPTILNATCILQVTSQTNVNRMWQNDLHPILIERYPGSPGSYAVRQHIKHRLQGLQAGWLVEEDTFQSHTPYGYRTFSNIISTLNPLAKRHLVIACHYDSKYFPPQLDGKVFVGATDSAVPCAMMLELARSLDRQLSFLKQSSLPPKADLSLKLIFFDGEEAFVRWSPSDSLYGSRSLAQKMASTPHPPGARNTYQIQGIDLFVLLDLIGARNPVFPVYFLNTARWFGRLEAIEQNLYDLGLLNNYSSERQYFRSNLRRHPVEDDHIPFLRRGVPILHLIPSPFPRVWHTMEDNEENLDKPTIDNLSKILQVFVLEYLNLG
What is the function of this protein?
Responsible for the biosynthesis of pyroglutamyl peptides.  Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue.  Also catalyzes N-terminal pyroglutamate formation (By similarity).
What are the official names of this protein?
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, Glutaminyl-tRNA cyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the glutaminyl-peptide cyclotransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSH_STAS1
Sequence: MSETKITYDDFNPHAFETLDITDETKGAREVIRWAYDVYGDSIIYSCSFGAEGMILIDLISSVKKDAEIVFLDTNLHFQETYDLIDRVKARYPELNIKLKQPSLTLEEQADQVAPALWKQDPNQCCYIRKIKPLEEVLSGATAWVSGLRREQSPSRQATNFINKDERFKSVKVCPLIHWTWDDVWDYIKAHDLHYNELHDFNFPSIGCIPCTEAVSGNGDSRAGRWTNSTKTECGLHTTNKP
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POB3_GIBZE
Sequence: MTAIESFDNIYLDLSKESGKCRFAETGFGWKPVGGGDTFTLDHNNIASAQWSRAAKGYEIKIVQRSKSGIIQLDGFQQEDYDRLAKVFKNWYSTVLESKEHALRGWNWGKAEFSKSELTFSVQNRPAFELPYSEIGNTNLAGRNEVAVEMALPESGANAQLGGARSKGSKAAAGRDQLVEMRFYIPGVTTRKEAEGEDAGSDAGNDEQEKNAATLFYETLIDKAEIGETAGDTIATFLDVLHLTPRGRFDIDMYEASFRLRGKTYDYKIQYEAIKKFMVLPKPDEVHYMLVMGLDPPLRQGQTRYPFVVMQFKKDEEVTIDLNLNEEELKSKYQDKLEPHYEEPLHQVVAKIFRGLGNRKISSPAKDFITHRNQYGIKCSIKASEGFLYCLEKAFMFVPKPATYIAYEQTQSVTFSRVSGAVSALSTFDITVLLKNGAGSSQFSNISREDLKALESFFKLKGLRVKNEIDEDANLLAAAMNQQMDDSEDEVAAKADRGSADEDEESVDEDFRTDSESDVAEEYDSAHESDGSGSDESNVDDDEQDDDDDDDDDDGEDEDERPKKKKKTG
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit POB3, Facilitates chromatin transcription complex subunit POB3.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: SFSA_DINSH
Sequence: MRFQTPLVPARLVRRYNRFLSDAVLEDTGEEVRAHCPNPGAMLGLKDAGQRIWLEPNDDPKKKLRYGWRLVELADGHMAGIDTSVPNKVVGEALAARAITELAAYGTIRAEVKYGTNSRVDFLATEPGLPDTYVEVKNVHLRRAEDWAEFPDSVTTRGAKHLAELARMVEAGHRAVMLYLVQRTDCTRLRLAPDLDPSYARAFDAARATGVEMLCYGTLIDTGGVTLGRALPVDPAAQAPQNED
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: AROA_MYCBT
Sequence: MKTWPAPTAPTPVRATVTVPGSKSQTNRALVLAALAAAQGRGASTISGALRSRDTELMLDALQTLGLRVDGVGSELTVSGRIEPGPGARVDCGLAGTVLRFVPPLAALGSVPVTFDGDQQARGRPIAPLLDALRELGVAVDGTGLPFRVRGNGSLAGGTVAIDASASSQFVSGLLLSAASFTDGLTVQHTGSSLPSAPHIAMTAAMLRQAGVDIDDSTPNRWQVRPGPVAARRWDIEPDLTNAVAFLSAAVVSGGTVRITGWPRVSVQPADHILAILRQLNAVVIHADSSLEVRGPTGYDGFDVDLRAVGELTPSVAALAALASPGSVSRLSGIAHLRGHETDRLAALSTEINRLGGTCRETPDGLVITATPLRPGIWRAYADHRMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWGYPQPRSGQRARRATGQGSGG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD1_DICDI
Sequence: MSTTASTSSNNLTFTSIVKSFFESYSKTPQKLKIIDLFLIYTFITGVIVFTYCCLVGTYPFNSFLAAFISTVGCFVLTVCLRIQINPINNFGKTISIERAFTDYLLCNLILHLVVFNFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Oligosaccharyl transferase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.