PharMolix/UniProtQA huggingface dataset:
Protein: VGP_MABVR
Sequence: MKTIYFLISLILIQSIKTLPVLEIASNSQPQDVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPSNIRDYPKCKTVHHIQGQNPHAQGIALHLWGAFFLYDRVASTTMYRGKVFTEGNIAAMIVNKTVHRMIFSRQGQGYRHMNLTSTNKYWTSSNETQRNDTGCFGILQEYNSTNNQTCPPSLKPPSLPTVTPSIHSTNTQINTAKSGTMNPSSDDEDLMISGSGSGEQGPHTTLNVVTEQKQSSTILSTPSLHPSTSQHEQNSTNPSRHAVTEHNGTDPTTQPATLLNNTNTTPTYNTLKYNLSTPSPPTRNITNNDTQRELAESEQTNAQLNTTLDPTENPTTGQDTNSTTNIIMTTSDITSKHPTNSSPDSSPTTRPPIYFRKKRSIFWKEGDIFPFLDGLINTEIDFDPIPNTETIFDESPSFNTSTNEEQHTPPNISLTFSYFPDKNGDTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAGLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDKIRKDEQKEETGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG
What is the function of this protein?
GP2 acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in GP2, releasing the fusion hydrophobic peptide (By similarity).
What are the official names of this protein?
Envelope glycoprotein, GP1,2, GP, Virion spike glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[GP2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site. SUBCELLULAR LOCATION: [GP1]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=GP1 is not anchored to the viral envelope, but forms a disulfid-linked complex with the extravirion surface GP2. In the cell, both GP1 and GP2 localize to the plasma membrane lipid rafts, which probably represent the assembly and budding site. GP1 can also be shed after proteolytic processing.
Protein: CRCB_RENSM
Sequence: MIVIFVGLAGVLGALMRFGLDSFFAQRGRFAHGQAHHFPLATLSVNVLGSFIIGLAGGFASHAELSPDWHSAISIGIAGGLTTFSSFAVATVSLWQLGNKFSAMVNIGLNLVLGLGAAWLGLSLAA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPA_CITK8
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDTNEPLKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPAIKIETLVPDFRGRMDRALEILNATPPDVFNHNLENVPRVYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFDEMKAEAMAMGFTHAACGPFVRSSYHADMQAKGLEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSM5_TRYBB
Sequence: MIHSNKVATVVLALISSWPADGTNNHGLKLQKAQAICKMSKELKATAMRAANDAKLKITEILELENVFAAMIPNATKGTEADGCTDYNAVFLEANNTAAETVSKIATLAESATKAAGAAGRAAGVLDEFIAALAQAQGATGLYCIQGSGTGAATHTELADCFNGDLKPRNMLSIRDPKVSAAATGSTDLTTLAKAMAASGTDTTFHGDQQSKGCGLMKGTSDGIMIGQALTGTFAWAQGLLRFGALGANGIASTGVTGYAHTATASGNGVHWASDPEKIPVIAEAIALVSNYNTLADSIGTRAKDAIEKVKKCMKATNKEIKREHIFLNVSHLNRELQKAVTELDKALNKQDAKAEAKQQPNCDDKKQIECGDTPGCGWHKAEGKCEAKDGEGQKNQATGEKDANKNRCTQHGTNKEACEKENTPGQSAVCGFRKGKDGETDEPDKEKCRNGSFLTSKQFAFSVVSAAFMALLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein MITAT 1.5, VSG 118.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: ROK1_MAGO7
Sequence: MDILKVLSRGTKQAPKKPGVPAATLAQANIPSAGVETNPQLYHDNVGPPPKGKKRKRKSRTQDHDQADDAVDDDVELSDFDFFAPKTRRDSDGAGSKTKAADVKKAKKDADEADKARPIELDECKRILRSHRLKYTLLPVQKAAPAKVEKSSAKKKKKKDKGDKVDGAAQAAQGKSDKLPVFPQPLVSFSQLRSAYRISPRLADNLAKGSYKVPTEVQLGALPLLLQPGFALSHEGDGVDDDGKGGDGEALAMLQGASAGVDFLAIAPTGSGKTLSFLLPAINGVLKRRAEKGETGGDSSNDTKHALEAIVVAPTRELASQIANEGRKLAMGTGVRVVLMRKGMRVAAEEDSTEKKSEDQEEDVFESEDEDSLSEDDEEREKSEKPSKKPNKAPITKADILVTTPMLLLNFLSKGTSTTKKRLPRVRSLILDEADVLLDQLFREQTMGIWSACRNPNLRVSFWSATMASNIETHILDNLRAQADDAPAPPLIRLVVGLKDTAVPNISHRLVYTATESGKLLALRQLLHPASFSTTTSSTTTPEDETPLRPPFLVFVQTIERATALHEELKYDIPAAAGGASRVAVLHSSMPESARAAVIRRFRAADVWVLITTDVLARGVDFAGVNGVVNYDVPGSAAAYVHRAGRTGRAGRKGGIAVTFYTKEDIPFVKNVANVIALSERQAGAGESATQKWLLDALPDVSKKDKKELREKGVESRRSVAASKGKARITSKSAWERRKENNRKGAIEGSKRRKIAARDQGDGSDDGGEWGGIDD
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase ROK1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EX7L_CLAM3
Sequence: MSETRSVSMPAADAPTVDAPWPVSVLSGKIKGWIDRLGTAWVEGEITQWGGSGGNVYGKLKDLDVDATISFTVWSSVRAKIPADLGQGARVVALVKPNYWVKGGTLTMQVLEMRHVGLGDLLERLERLRQTLRAEGLFDADRKRRLPFLPGCIGLITGKDSDAEKDVLRNAQLRWPSVRFRVVHTAVQGDRAAGEVTRAIGVLDEDPEVDVIVIARGGGDFQNLLVFSDEKLVRTAAACRTPLVSAIGHEADRPLLDDVADLRASTPTDAAKRVVPDVSEELSRVQQARARIGMRLTSQVRGEIDRIEQLRSRPVLSSTAWIVDSRAEELGRYIARSAELAGRVVERGMQQTSELSRQLRTLSPQHVLDRGYAIVQTADGSALRAPADAPDGTGLALRLAAGALGATSTGPTDDIPSSAARLPSSPAPDARPASGAES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMOD3_DANRE
Sequence: MSERTEQESYTDKIDEDEILAGLSAEELKQLQSEMDDIAPDERVPVGLRQKDASHEMTVRDCTEPESEEEIDEDEILAGLSAEELKQLQSEMEEIAPDERVPVGMRQRDQTDKPPTGSFDHRSLVEYLYWEKESKRMLEEERVPTTLLPSQKTNEEHEAKNEDKVEELELVYEEIVEEVEGGQGDAVVDEVIEEVIMEVEEEDKVCDKPVKTDLDATDPTVTSEDGLQRPSESADANVEAKTDQSGLDTETKVNEEKKEDSTEPAPSSYENWVPEKEERVISKLKIPKLALGGNTFVKKTARPSGNETNLESTLDKIRNNNPSVTDVNLNNIENIPKEMLLDYVNSLKKNRHVKTFSIANTGADENVAFTLANMLKENRSITTLNIESNFITGKGIVAIIRCLQFNETLTELRFHNQRHMLGHHAEMEVSRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNLDRQRQQRMEEQKLQQMKEQRKVMEMYEDSLNLPPGMLEMLGGYIPLSLLQNCQNGAEDIPEDSPEPSPQPSPPHQLCKTQHLAPQQHPPNLSTGNLFEEVQLKKTPKRRDPLLEWNQCDERKDGRPNVHLRSVPKKRSIAREGPVDERANLKDMIKTLKPVPRRREPPKVDLTPRDHLLSEIRQSNVAYLKAVPLPKILESQETSLF
What is the function of this protein?
Essential for the organization of sarcomeric thin filaments in skeletal muscle.
What are the official names of this protein?
Leiomodin-3.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton.
Protein: SECD_BORBU
Sequence: MKKGSKLILILLVTFFACLLIFPTLKWYFLMSVEDKKISSYSQEALRDYSKKKALNDLVKLKELYNKDPNSSIPASLSYLIPIAKNNYRSSMKIPPNIFTAKTLREGFLTDSDMGEVSLEIYRYYENIKKGKSRIIHLGLDLSGGMSVTISLDYSSVEKKLGRSLTFAEREDAIYRIMQILKDRVBRFGLTEPKIVREAGGNKIFLDIPGEKDESRVSTLLSGKGNLTFYVVDDESTSLLHRKILEAGSLFSIPEIQASMNLPDSKQIFPWYVKDSYGVDDESSVRYYVVDASPENSFDGAHIKDAGVSNDPRTGRDTVAFSLDVDGSEKFFKFTQKNVGKSLAVVMEGKIKSVAGIGYAITGGNVSIQGDSFDKKEAQDLALVFKTAAFPVDIKIDDLRIIGPTLGARTIDLGIKASALALCLVFLFICVYYGLSGVVAGFSLVIYNVFLILAILSAFNFTLTLTSIAGLILTMGMAVDINIVIYERIKEEIREGRRFENAFEAGFKKAFLSIMDANITTFIAVLFLTLLGTGVIQGFAWSLSVGIVASLFSSLIFSRFILEFIISVRKSKFISISWSSKYAKSN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_BORPA
Sequence: MTTAENRARLVLGNWKMHGNLAENAALLAELRAADAAAHCEMGVCVPFPYLAQTAAALQGSAIGWGAQDVSAHAKGAYTGEVAAPMLAEFGCRWVLVGHSERRTLHAESDQLVADKARAALEAGLTPVVCVGESLQEREGGNTLGVIERQLEPVLALGRDALVRMVLAYEPVWAIGTGRTASPEQAQEVHSAIRVALDGLQASQVRVLYGGSVKGANAASLFAMPDIDGGLVGGASLVAEEFLRIAAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2072_AROAE
Sequence: MAGHSKWANIQHRKGRQDAKRGKVFTKLIKEITVAARMGGGDPNFNPRLRLAVDKAKAENMPSENIDRAIKRGTGELDGVSYEEARYEGYGIGGAAVMVDCLTDNKTRTVADVRHAFSKNGGNMGTDGCVAFQFKHCGQLMFAPGTSEDALMEAALEAGAEDVVTNDDGSIEVITAPYEYSNVKDALEKASFRAEFGEVTMKPQNETELSGGDAERMQKLLDALESLDDVQEVYTSAVMDE
What are the official names of this protein?
Probable transcriptional regulatory protein AZOSEA20720.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQO1_PARDE
Sequence: MLNDQDRIFTNLYGMGDRSLAGAKKRGHWDGTAAIIQRGRDKIIDEMKASGLRGRGGAGFPTGMKWSFMPKESDGRPSYLVINADESEPATCKDREIMRHDPHTLIEGALIASFAMGAHAAYIYIRGEFIREREALQAAIDECYDAGLLGRNAAGSGWDFDLYLHHGAGAYICGEETALLESLEGKKGMPRMKPPFPAGAGLYGCPTTVNNVESIAVVPTILRRGAEWFASFGRPNNAGVKLFGLTGHVNTPCVVEEAMSIPMRELIEKHGGGIRGGWKNLKAVIPGGASCPVLTAEQCENAIMDYDGMRDVRSSFGTACMIVMDQSTDVVKAIWRLSKFFKHESCGQCTPCREGTGWMMRVMERLVRGDAEVEEIDMLFDVTKQVEGHTICALGDAAAWPIQGLIRNFREEIEDRIKAKRTGRMGAMAAE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase chain 1, NADH dehydrogenase I, chain 1, NDH-1, chain 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS30_PIG
Sequence: KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS
What are the official names of this protein?
40S ribosomal protein S30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS30 family.
Protein: OBL1_ARATH
Sequence: MHKDNDSGSGSNPGQVSNYLIVRPHRGGYIDLFRYGVRDDQTSKAKFLEMPDNREWSTITIDEEAEDHRWVIVVSILVRKIIRLLRTPMEFTGFVVDFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLYKEWNFVEHLEGIDSVDSGRVKIELGSRGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDADDWGTDFDYSWYEVPNVGKLHMGFLEAMGLGNRDDTTTFHYNLFEQTSSEEENSKKNLLDMVERSAYYAVRVILKRLLSEHENARFVVTGHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIVPRLPYDDKTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRLMGLVIPGLSDHCMTDYVNSVRLGPDNELQMSSL
What is the function of this protein?
Acid lipase that can hydrolyze a range of triacylglycerols without a clear preference for acyl-chains (PubMed:29178188).  Can also cleave 1,2-diacylglycerol, 1,3-diacylglycerol and 1-monoacylglycerol, but not phospatidylcholine, phosphatidylethanolamine, or sterol esters (PubMed:29178188).  Required for pollen tube growth (PubMed:29178188).  Triacylglycerol hydrolysis by OBL1 may provide acyl groups for the synthesis of membrane lipids in growing pollen tubes (Probable).
What are the official names of this protein?
Triacylglycerol lipase OBL1, Oil body lipase 1, AtOBL1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Single-pass membrane protein. Note=Associates with the oil body membrane.
Protein: DUS3_AJECN
Sequence: MDSDNDVTLSQTKTAGSSGTEVYKQNGHVRAEEFEESLAKRIKLDGQPVSGLQTAANGGVGRRKGVAPVKKEYLIEVSQSTGQASPRAIADDDAAEAAKHHEKDGGGAKQKGRREKKGGQNIKRTFGRSQDEKQLCQTVAYYPEFSPNPCAFGKSCKFEHDIRKYLKNYKRADLDTFGGVCPVWEAKGRCPSGWKCRFVGSHMAERETEDGRKELVLVEDASRMRHPTSTNGIEVDGVVNVVTTEAKLALAKKRYQTPKADSYTTWIDTVSREVERNLHGRNQDEAASVPGNADGQGTSDSKDRKEDNRAQYTEPPFLPSEKRRLYFGPETPVLAPLTTQGNLPFRRLCVDLGAQLTYSEMAMSMSLVQGSKSEWALMKAHESETLPPAVNPKQTIVKDYDNSRDLKFGAQITGNKPWVALRATEAMTALCPQLRVIDMNCGCPIDMVFREGSGSALLDHASKLEKMLRGMNAVSGEIPITAKIRMGTKDSNPTATKLIERLIMGGVESHEIGRGPAGVAAITLHGRSRQQRYSRQADWEYISQCAALVKRLNEQTDIGTDTIKEPDARDQPSAGKVFFLGNGDCYSHEDYFNGIQKSGVDTVMVARGALVKPWIFEEIEKGQYLDKSASERLALVEKFARYGLEAWGSDEYGVGNTRRFLLEYLSFTHRYIPVGILEYLPPSIQDRPPAWKGRNELETLLGSDNYKDWIKISEMFLGPAHKDFKFEPKHKSNSYEIVAEG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARNA_PHOLL
Sequence: MKAIVFAYHDIGCVGINALTKAGFDIQAVFTHTDDPNENHFFSSVARLSADLALPVFAPENVNHPLWIERIRELKPDVIFSFYYRDMLSEDILSLASTGAFNLHGSLLPKYRGRAPINWAILNGEVETGVTLHKMVLKPDAGDIIAQYKVAIAETDTALTLHGKIREAAEKLFDQVLPQIKAGIYPAIPQDESQATYFGRRTAVDGEIDWHKSATEINNLVRAVTEPYPGAFTFLGERKITIWRACPLNETHDKQPGTVLSVDPLIIACGKGTLEIINGQSESGLYVQGHRLAVDMSMVTDVRVGPKATTQINHRKRVLILGVNGFIGNHLTERLLRDGNYDIYGMDIGSSAIERFISNPRFHFIEGDINIHTEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKIVRYCVKYNKRIIFPSTSEVYGMCDDKEFDEDDSRLIVGPINKQRWIYSVSKQLLDRVIWAYGEKEGLKFTLFRPFNWMGPRLDNLNSARIGSSRAITQLILNLVEGSPIKLVDGGEQKRCFTDINDGIEALFRIIENREGLCDGQIINIGNPTNEASIRQLAEILLDSFEDHELRDHFPPFAGFKKVESGSYYGKGYQDVEHRKPSIKNAERLLDWKPTIDMKQTINETLDFFLRGAVEELGKN
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: AFP4_GADMO
Sequence: MKYTLIAAIVVLALAQGTLAVEQSPELEKMAQFFEGMKTELMATVQKVSESLQSQTIIEDGRTQLEPIMTQIQEHLAPLATSVQEKVTPLAEDMQQKLKPYVDEFQSELESVLRKLLDQAKAITQ
What is the function of this protein?
Antifreeze proteins lower the blood freezing point.
What are the official names of this protein?
Type-4 ice-structuring protein, Antifreeze protein type IV.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPR1B_MOUSE
Sequence: MSSHQQKQPCTAPPQLHEQQVKQPCQPPPPEPCVSQVKTPCDTKVPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKVPEPCLPKAPEPCQPIVPEPCPSTVTPILAQQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane.
What are the official names of this protein?
Cornifin-B, Small proline-rich protein 1B, SPR1 B, SPR1B.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNXMA_SCOMU
Sequence: MTVSCSKVLLSLCLFLILLEATHESNQQRTNYREFSEIQLAQETREINEKNNQLLNQQLPRLNRRKRLWRDEDRRTFCTTLCPCEDRRKRAAVTPPTRKVPCCCP
What are the official names of this protein?
Putative neurotoxin 10.
What is the protein family that this protein belongs to?
Belongs to the scolopendra neurotoxin 10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFE_YERPE
Sequence: MSEAKNLLAQGLWKNNSALVQLLGLCPLLAVSSTATNALGLGLATTLVLVCTNTAVSALRRWVPSEIRIPIYVMIIASVVSTVQMLINAYAFGLYQSLGIFIPLIVTNCIVIGRAEAYAAKNPVGLSALDGFAMGMGATCALFVLGALREILGNGTLFDGADMLLGSWATVLRIDILHLDTPFLLAMLPPGAFIGLGLLLAGKYVIDEKMKARKANTRVSVPQLQDGDAEKAL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_SPIKU
Sequence: MKKFTVLTLFPEMFNNFMTTSIIKKALYEKLIAIKIINIRDYSIGKHYQVDDYQYGGGEGMVLMIEPLVAAIKAQQTRDSVTILLTPQGKQYVQEQVQQFAANDNDLILVCGHYEGFDERILYYIDYELSIGDYILTGGELASMVVIDSVTRLCENVINTQSHLNDSFSKNLLDYPVYTKPVEYGGHYVPEVLLSGHHQKIAQWREYEALKKTWLKRPYLLEKKILTTEQQIFLEKIKNEKSFNDRRKEKNSYEDEFNRRNYKRSTS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_ECO45
Sequence: MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXYD6_PONAB
Sequence: MELVLVFLCSLLAPTVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
What are the official names of this protein?
FXYD domain-containing ion transport regulator 6, Phosphohippolin.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DCTA_SALAR
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDIIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQLGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDRQKLDDVLNNRAPDGKTHEISS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_SPHAL
Sequence: MAKAKFERTKPHCNIGTIGHVDHGKTSLTAAITKVLAENVAGNAAVDFANIDKAPEERERGITISTAHVEYETESRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTKEHILLAKQVGVPTMVVFLNKVDQLDDPELLELVELEIREELSKRDFDGDNIPIIAGSALAALEGRDDNIGKDAILKLMAAVDEWIPQPERPLDKPFLMPIEDVFSISGRGTVVTGRVETGVVKVGEEVEIVGIKDTKKTVVTGVEMFRKLLDQGQAGDNIGALIRGVGREEVERGQVLAKPGSITPHTEFTSEVYVLSKDEGGRHTPFFANYRPQFYFRTTDVTGEVILPEGTEMVMPGDNVQLSVKLIAPIAMDPGLRFAIREGGRTVGAGVVATVTK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_BORBU
Sequence: MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEHEFSKVNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVLVVPTPVVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLRRDISKRGRTVESVIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSKEGLDFT
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.