PharMolix/UniProtQA huggingface dataset:
Protein: PDK1_CRYNH
Sequence: MASSHFGPASPASSTPPPSSAYARLIAPTITRNSSSSSSRSTTTCSSTSSVQAVPMRPPPIETSTAATSRSQLPSNRHSENEAEHDTSYTSPGLSVGGRGGLARNGPRSNRLGTSPQARHVPPSIVALSPSPSPILNMASKRQSNTETVSGTSPSTPLGKSFLAQQDLSPNSSTIPLRVTISVDPNDRLSHDRESHSAERPRSSGNSPVRGRHGHLSTPSSPTNSYRALGGKPRTLSVDAGQNWGGSHRSRARDGDDRERRQSQVSSASSGALKKHSLDDWVLGEELGVGSYSTVYCVTPSANTHSPTSPQPARKYALKVINQAHLIQEKKVKYAMVERDALIRLSDPRPSKGHKRGVSSSSSSGYAQTGSAGKRRSTASIGGQSSMASVSGGTVSNSKKDTRDRLSIVTTSSAASSPVLTASSGSTQLSPTAVSGGGGNIKGRRPSRSAEPPTPVQEQTEMLIRGGEDGKDGQDGQETPSREWDRDRDWDNMTRSRPPSPVREESAEGGEKEKDEEERSGAEPVELGAAIHLTLPPPQIPSTPEPRGSPLLSTDGHRTSRETPRDRPHLTPKRRRQSLAPSERSVKSASTTGKMSAAAHPGVVRLYSTFNDSSSLYFVLSLASNGELASIIRKHGSLDITSARYYAAQLIDTLEFVHSRGVIHRDLKPENILLDEDMRIKITDFGSAKIIAKDEPIVDDSSRSRSFVGSADFVSPEVLRNEVATTASDIWAFGCVLYQFICGKPPFRGATDYLTFQKILKREVEFPKGIDEDAKSLIDTILDLEPNLRPSITFIKTHPFFQSIDFSTLWTIPAPPISSGLREPSKSTTLAQLEASDIWGVFEGSDVGEEDEDGFEYDADTVSPRPEGGAVGEGMMEPLFDRRAAASAVHNVDHPKFSRLRNQYINLGEDLDPPRPAYAGAGTGGRGKREKEVEKKKGEKARGLSHGSESSGGNRSALAGWLEAIKFGGAGGGGMSGSATSVAASDTVRTPGTGTGTGPGSRPGSRAGIPSFGLGPGSGSRSNRGSGASMRSDEARDLSMSLGGLRMNMSKASEFDKWTPLLLANESIIFTSPITLRTSSPALQLHLPAFLLPAPKKRQLVLTDFPRLLMIKDDNEADGDPAGSDSGAGLSSSSHVESGGGGVGGGGRGGGHGSLRIKGEAVFVPRPSTATGSSTTKGGGYSAVPNAVMDVQEKGSKGFTVQTPGMVYYCHVDSVELRAKWMAAIHRVGL
What is the function of this protein?
Serine/threonine-protein kinase that functions in the sphingolipid-mediated signaling pathway, regulating organization of the plasma membrane (By similarity).  May phosphorylate PKC1 to activate the cell integrity MAPK cascade during cell wall and membrane stress (PubMed:22339665, PubMed:23087368).  May regulate sphingolipid metabolism upstream of YPK1 (PubMed:22339665).
What are the official names of this protein?
Serine/threonine-protein kinase PDK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
Protein: LEUC_BACCZ
Sequence: MGKRLLDKLWEKHVVTTNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRKVRRPDLTFATMDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGAMEMEERMTLCNMAIEGGAKAGIIAPDEKTFAYVKGRKYAPRDYETFEKKWSELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRIDEKLPEKHDVNDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAAAVVKGRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAALYGHFVDTRKESYDGAISYS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PSAE_PROM2
Sequence: MAIARGDFVRIKRPESYWYNEIGKVASIDKTGIKYNCTVRFDKCNYAGISGTAEGATTNMFAESELEKA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: MTHFS_CAEEL
Sequence: MSAIKEVKSELRQFMKTLLGKISKEETQRQTEAVFEKIIESKWFQESKRLSVYVSTSGEIQTDSIIQKALEMGKEVFIPQFTKGSTAMDMVRVPDQTAFDNLPSTLWGIRQPEPKWKWQSYHETGPLDLILAPGVAFSPYGLRCGHGKGYYDRFFSTHHKHFPENSPKKIGLALREQIIGTIPISETDVELDEVIYEGETIIFDTI
What is the function of this protein?
Contributes to tetrahydrofolate metabolism.  Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.  Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10-methenyltetrahydrofolate (By similarity).
What are the official names of this protein?
Probable 5-formyltetrahydrofolate cyclo-ligase, 5,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase.
What is the protein family that this protein belongs to?
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_BURP0
Sequence: MATIKVDVVSAEEQIFSGQAKFVALPGEAGELGILPGHTPLITRIRPGAVRIESESGDEEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDIDLAKAQSELATAMAQLEAIQRLAKIRGKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MNTP_SHIF8
Sequence: MNITATVLLAFGMSMDAFAASIGKGAPLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPA_PROMS
Sequence: MAIPKDMRLKGHRTFNYIHKNSMTYHGKLMTFKVARSNPEILLTHKLTNTSNNFRVAIAISKKVSKKAVERNKLRRILQEWLLTNIQKINNHKPYWLLVNLKFGDFRNDKSKLLEEFQNLMFKSRLIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: M1_I33A0
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEVLMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMDIASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: WAXS9_ARATH
Sequence: MEEELKNFIIVWISAIISVSYCYYISANIKTGVLRLFSVLPICGLFFVLPLFFSSVHFSSSTAFYLSEMASLKLILFAFDQGPLFPVAPNLIQFVCFTCFPIKLQRNPKSQPSQNHFHKRAFAIKIMIFGVVLHVYNYSHFLPQTVLLSLCFLHLYVELEILLGPLKVLLSMALGCDLEPQFNKPYLATSLQDFWGRRWNLMVSSVLRSGIYNPVRCACQRPMNSGWARFMGYLVTFLVSGLFHELVYFYITRETPTWEVTLFFVLNGVCTGTEVAVKRTAFLQRWWPVRSSVSRLLTMGFVVVTGGLLFFPLFIRSGMMERRANETLFFLDFVKRKFSIF
What is the function of this protein?
Catalyzes the final step in the synthesis of long-chain linear esters (waxes).
What are the official names of this protein?
Probable long-chain-alcohol O-fatty-acyltransferase 9, Wax synthase 9.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AXP1_YARLI
Sequence: MQFSLATLTTLLAFVAAAPANKGFVHAPIKKQSLQAAQSKIPNFASSGPITAELYNELMAYQVQISLGGQTISASIDTGSEILWVWENDSIACQVDQQDCDTDGSYNPKKSSTSKDTGVPFNINYGKGHADGYLYTDNAVIGGASAPGFKFGVNSGDLSSGGFSMVFGIGVNSDASTSISAQLQKSGEISRNLYGMSFSDANLAGTSNDNSEITFGAINTGRYTGSLKTIPRVATQGGYQHFSVSASGKFGDVDLFDNDLVILDSGTTMTYLKSDYYNAFLGGLEDLDITLSDYSGGWHGYPCSENSKINFTYNFSGKEITVTGHDLAIPGNAVNSNVDSSVCFMGVDDGGNMNLFGDTFLRAIYSVYDLERDEVSIAQAAHGKPDNYVVITGDVPN
What are the official names of this protein?
Acid extracellular protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y7093_BURP0
Sequence: MLRYALIFFIIAIIAAVLGFGGIAAGAAEIAKILFYIFVVIFLVTLVLGVARR
What are the official names of this protein?
UPF0391 membrane protein BURPS1106A_A2993.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KIFC3_HUMAN
Sequence: MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV
What is the function of this protein?
Minus-end microtubule-dependent motor protein.  Involved in apically targeted transport (By similarity).  Required for zonula adherens maintenance.
What are the official names of this protein?
Kinesin-like protein KIFC3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell-cell contacts.
Protein: Y1044_ARATH
Sequence: MACMKLGSKSDAFQRQGQAWFCTTGLPSDIVVEVGEMSFHLHKFPLLSRSGVMERRIAEASKEGDDKCLIEISDLPGGDKTFELVAKFCYGVKLELTASNVVYLRCAAEHLEMTEEHGEGNLISQTETFFNQVVLKSWKDSIKALHSCDEVLEYADELNITKKCIESLAMRASTDPNLFGWPVVEHGGPMQSPGGSVLWNGISTGARPKHTSSDWWYEDASMLSFPLFKRLITVMESRGIREDIIAGSLTYYTRKHLPGLKRRRGGPESSGRFSTPLGSGNVLSEEEQKNLLEEIQELLRMQKGLVPTKFFVDMLRIAKILKASPDCIANLEKRIGMQLDQAALEDLVMPSFSHTMETLYDVDSVQRILDHFLGTDQIMPGGVGSPCSSVDDGNLIGSPQSITPMTAVAKLIDGYLAEVAPDVNLKLPKFQALAASIPEYARLLDDGLYRAIDIYLKHHPWLAETERENLCRLLDCQKLSLEACTHAAQNERLPLRIIVQVLFFEQLQLRTSVAGCFLVSDNLDGGSRQLRSGGYVGGPNEGGGGGGGWATAVRENQVLKVGMDSMRMRVCELEKECSNMRQEIEKLGKTTKGGGSASNGVGSKTWENVSKKLGFGFKLKSHQMCSAQEGSVSKSNNENVKIEKLKDVKERRGKHKKASSISSER
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At1g30440.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: S2538_ASHGO
Sequence: MSEKAGGVPAHLVSGFFGGLASVCALQPLDLLKTRLQQAQASSLRSVLREVRTTRELWRGTLPSALRTSIGSALYLSLLNYSRSALARGSEARTRSSLLPRLQSYQNLLTGALSRAAVGLVTMPITVIKVRYESTLYAYNGLAEATRHIWRSEGARGFFKGAAATTLRDAPYAGLYVLLYEQAKEMLPRALPATLLGADESGKLTAPASAMVNGVSAFLSASLATTLTAPFDTIKTRMQLQSHPVGFVQTLRHIVCEERARTLFDGLSLRLCRKAMSACIAWGIYEELLKLLH
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AMY1_SCHOC
Sequence: MRFSTEGFTSKVVAAILAFSRLVSAQPIIFDMRDVSSSADKWKDQSIYQIVTDRFARSDGSTTADCLVSDRKYCGGSYKGIIDKLDYIQGMGFTAIWISPVVEQIPDNTAYGYAYHGYWMKNIDELNTNFGTADELKQLASELHSRSMLLMVDVVYNHYAWNGDGSSVDYSSFTPFNQQSYFHDYCLITNYNDQTNVEDCWEGDTEVSLPDLSTEDNEVIGVFQTWVSDFVQNYSIDGLRIDSAKHVDTASLTKFEDASGVYNLGEVYQGDPTYTCPYQNYMKGVTNYPLYYPVYRFFSDTSATSSELTSMISTLQSSCSDVSLLGNFIENHDQVRFPSVTSDTSLIKNDMAFIILGDGIPIIYYGQEQGLNGGSDPANREALWLSGYNTDSEYYELISKLNQIRNQAIKKDSAYSTYKSSVVSSSDHYIATRKGSDANQLISIFNNLGSNGSQDITVSNTGYSSGDKVIDIISCNSVLAGDSGSLSVSISGGMPQVYAPSSVLSGSGICNQ
What are the official names of this protein?
Alpha-amylase 1, 1,4-alpha-D-glucan glucanohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: CPXP_SINFN
Sequence: MPEQPLPTLPMWRVDHIEPSPTMLALRANGPIHNVRFPRGHEGWWVTGYDEAKAVLSDAAFRPAGMPPAAFTPDCVILGSPGWLVSHEGGEHARLRTIVAPAFSDRRVKLLAQQVEAIAAQLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAFFAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMRDKRQDPGDNLLTDLLAAVDRGEATEEEAIGLAAGMLVAGHESTVAQIEFGLLAMLRHPQQRERLVGNPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGVHIPAESKVLVGLPATSFDPRHFEDPEIFDIGRDAKPHLAFSYGPHYCIGMALARLELKVVFGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 BJ-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SYGA_HELMI
Sequence: MNFQEIILALNQFWGEQGCIIQQPYDVEKGAGTMNPATFLRALGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQYQVILKPSPDDVLEMYLDSLRRLGIDPLKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQCGGIDCRPVCAEITYGIERIAMFIQQKDSVYDIEWVEGITYGDVHHQGEVDYSHYNFEVADTAALFTFFDMYEKEALRVIEKGLVQPAYDYVLKCSHTFNLLDARGAISVTERTSFITRVRHLARVCAQAYVKQRERLRYPLIKDPAQRQRLGLDRENTGE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y238_AFV2P
Sequence: MTRVITFVGNVTLLSKVIVKNKLTDVYVDQSYLYKVSDNGVKLPSTNEKAIFFKQDDINIQNLVSEGDGEITKGVGEKVRFHFVDTGIPPFKTSPSLMYSDGSDNEIVEMINRRVRIAKLISLIVNEIDDDLMFIDSDITVNNIDALLYSMSNRTKIGTLCIPAIAKPYNFVIMFCASTNFYLPREMRNDLLNVIQRYIASAKYVNTPVDIFINRELGSTPITWFGVCHHKYDKEWCI
What are the official names of this protein?
Uncharacterized protein ORF238.
Protein: MUTL_SHEHH
Sequence: MAIEKLPPQLANQIAAGEVVERPASVIKELVENSLDAGATRVDIEIEKGGSKLIRIRDNGSGIPKADLCLALSRHATSKLKSLDDLEAILSFGFRGEALASISSVSRLILTSRTAEQAEAWQAHAEGTEMAVKVLPAAHPVGSTVEAVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALARRDIHFTLKHNGKTVRNYRPANTESQYIQRLALVCGKAFAETCLRIECQHNDLSLSGYLQSPSSANGYSETQYFYVNGRLVKDRLVNHAVRQAFAQYAEGVSPGYVLMLDLDPHQVDVNVHPAKHEVRFHQSRYVHDFILQALQSAISQSMELALNNEPEIQQSPDRQVSPTRGAVTAPLYSESIERKPSVSYDVRDSHSVTNQRDYSSGSSSYRSPLKPSARNGDVSLPSQSSIRAYGELLSTQSSSTHSDRVLSTQQNNYAVRSPAGNQNGLAASNSHAASMPAVIAGEFWVLVRDDKISLLSISMVARAVLKAEIAAKFSQGLVGQPLLMPVAVAVDDDWLAIIENREQLLRKLGIELSIRLGQLIIKKVPPYLRNSQLAVLIPELLQWIQLELPSDAAVVKWLAEQGANRFTSAGEAWFGLNALPDDVQRELYNLSQDLPWEQWMKENQSDR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: NIFU_FRAAL
Sequence: MAQVRHLLGSTPGHRGLRLRIGVDPGGCSGYTYKLALVPGAETGDVVLPQDGFDVVVHTTGVDLLRGMRVDYTETLTSSGFTFANPNAKSSCGCGSSFGSSDDPERTAADAKLPRTQVEEIMEEIRPMLRGDGGTPRSSPSSRGRSAGSAEVHLRLTGACGGCSSANATLTGVIEARLRQQLPEIGRVALVA
What is the function of this protein?
May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
What are the official names of this protein?
Nitrogen fixation protein NifU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: PGAM5_DROPE
Sequence: MRKFTAFACGTGAGLLTFYLTKLNEPKAAVHNSWTRSEKPVDPCALWDHNWDLRDPKSLVKPVKNDLSQEQNRYNTELEKVVPKHARHIILIRHGEYLDVGDTDETHHLTERGREQAKYTGKRLCELGIKWDKVIASTMVRAQETADIILNEIDYEKTKVKNCAFLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFYRAYPDQTKDSYTLLVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPVNHLTNRIPRAAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: GARL3_HUMAN
Sequence: MVVDFCRRFVARSLCIILMKHFCSSSVSEDLGCRRGDFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENATALPGTWRRTDVHLENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPYSPTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGLDTKNDTTGIHSVYTVYQGHEIMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRYNQQNDNYRLKIFSEESVPLFGPPLPTPPVFTDHQEFRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLHQDLMPDLHKNMLNRRSFSDVLPESPKSARKKEEARQAEFVRIGQALKLKSIVRGDAPSSLAASGICKKEPWEPQCFCSNFPHEAVCADPWGQALLVSTDAGVLLVDDDLPSVPVFDRTLPVKQMHVLETLDLLVLRADKGKDARLFVFRLSALQKGLEGKQAGKSRSDCRENKLEKTKGCHLYAINTHHSRELRIVVAIRNKLLLITRKHNKPSGVTSTSLLSPLSESPVEEFQYIREICLSDSPMVMTLVDGPAEESDNLICVAYRHQFDVVNESTGEAFRLHHVEANRVNFVAAIDVYEDGEAGLLLCYNYSCIYKKVCPFNGGSFLVQPSASDFQFCWNQAPYAIVCAFPYLLAFTTDSMEIRLVVNGNLVHTAVVPQLQLVASRSDIYFTATAAVNEVSSGGSSKGASARNSPQTPPGRDTPVFPSSLGEGEIQSKNLYKIPLRNLVGRSIERPLKSPLVSKVITPPTPISVGLAAIPVTHSLSLSRMEIKEIASRTRRELLGLSDEGGPKSEGAPKAKSKPRKRLEESQGGPKPGAVRSSSSDRIPSGSLESASTSEANPEGHSASSDQDPVADREGSPVSGSSPFQLTAFSDEDIIDLK
What are the official names of this protein?
GTPase-activating Rap/Ran-GAP domain-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the GARNL3 family.
Protein: CLU_ASHGO
Sequence: MSKELDTVEVSIRVPFGKSKRLSTTASRRARVQSIMYFLAFNAASKYYTNYELLHNGVEVDEQQLISELAGNEQTVHLQLRLKPYNTGEVIRHFVTFREYIGFVGDSDDDITSLALSNVAKFRELPLTDIAAASGKTEVADDRQKEEFQVSDAEKAVFTKELDSILELRPSAQDVLKGGSALSKPCLRSLIISGYNPVPAFFRTKGHLLYLQAVTLEGETLHITATVSGFYVNKSSAIKFDPTLKTDAAVCLTLYELLTKHSKKFASHLSQLEAALKAHESVNYVKPISVFLHKTWFPSSLPSNSIDFTEYQLEALNFQTERNFNDEFQAVKETSSEDIVARLEKEKLLNRVIHDFNVAASKGSMEIFYGNMVAMNPDAPRQEHIFLKNNIFYSFVSDLDGHYQDKGGDAAAHAASNQDLHIIKTLLQSNMRSVRHLLTAVVEFGGVRILAQSPVPGILDTAGMKFIKNEKGEEEAIQAKNDITVCYGFDEASNKVIADAEFGSSLDDFAKVFHLKKHEVDGVELKVASTSKGVVGFDKRNYILDLADNNPLDVGFALENFDAVTDEKARYPHRQTLLRRELVEKWWFSKVDGTGSEMEAAYEEGKFSYNPDAYKIEGIEDETVVELSDYLRKEVVPTLVKEVAEGSITAPFNGEHLVDIMHKNGINIRYLGRVIELAEQELEAQRALREAHLQQVEADNKEFTEWEANYLKHIESLIKERQVTIQKLLAEGKEVPAELKEELKLDDKEIRKPHEKEGVAVNNDQLSVLLTLAQIEIISRSIKHVFRKHCHELPAVIIPTFIAFALNLLFGYCYNKAPIAEFPTDGSDIDFAFTKLTREQLLSEISEQAVLRFRYTLPDGWESRYEHTPFALLRPICNKFGIQLLNKEYFFTREQYQNWRQAQDKKIRSKLVEPVSTFSINDLSVRPIIKVATLTTGVSDDCWAQGAYMINEEEKQATALALFSQSIAFREETSGYVHPTVAESYLALSTIHSKLEKKSEAVALCRKACAIYERVCGFDSFEMIRSLNNLAMLEMANDSPYNAALCLKTIMSILSVVIPVNHPATINSYSMLHSMCSSLQNSSAMIKVLNKLGDIIVEIDGHKSLPYAVNESRLANLYASVGEYKRSLACIESCYELFSKELGVNHKTTVECNSWITGVENLIESTSQSKALAASKAAAAAKQGEKKPAQKQQQSAELRDKSIDELMNFINGGSAPAKKSKKKKNAKK
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPK1_ENTH1
Sequence: MTTKQTVSLFIWLPESKQKTLFISTKNHTQFELNNIIFDVTLSTELPDKEPNAIITKRTHPVGKMADEMRKYEKDHPKVLFLESSAIHDMMSSREEINALLIKNNIPIPNSFSVKSKEEVIQLLQSKQLILPFIVKPENAQGTFNAHQMKIVLEQEGIDDIHFPCLCQHYINHNNKIVKVFCIGNTLKWQTRTSLPNVHRCGIKSVDFNNQHLEDILSWPEGVIDKQDIIENSANRFGSKILEDPILLNLTSEAEMRDLAYKVRCALGVQLCGIDFIKENEQGNPLVVDVNVFPSYGGKVDFDWFVEKVALCYTEVAKI
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.  Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5.  This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not.  Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.  May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium.
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase, Inositol 1,3,4-trisphosphate 5/6-kinase, Inositol-triphosphate 5/6-kinase, Ins(1,3,4)P(3) 5/6-kinase.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
Protein: RL361_ECOSM
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SEM3D_MOUSE
Sequence: MNVTKDENPRSRSQDLHLFHAWMMLIMTVLFLPVTETSKQNIPRLKLTYKDLLLSNTCIPFLGSSEGLDFQTLLLDEERGILLLGAKDHVFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANAECANFIRVLQPYNKTHVYVCGTGAFHPLCGYIDLGANKEELIFKLDTHNLESGRLKCPFDPQQPFASVMTDEHLYSGTASDFLGKDTAFTRSLGLMQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQEGSTSDRSILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQVFKHPTAILNMELSLKQQQLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQASVEWYIQRSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTLNVIENEQMENTQRAEYQEGQVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWYKEKRRQRNKGSPKWKHMQEMKKKRNRRHHRDLDELQRSVAT
What is the function of this protein?
Induces the collapse and paralysis of neuronal growth cones.  Could potentially act as repulsive cues toward specific neuronal populations.  Binds to neuropilin (By similarity).
What are the official names of this protein?
Semaphorin-3D.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.