PharMolix/UniProtQA huggingface dataset:
Protein: NGFV1_DEMVE
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHKALKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLENEDALNRNIRSKRENHPVNDHGEYSVCDSVSVWVNKTTATDIKGKPVTVMVDVNLNNHVYKQYFFETKCKNPNPVPSGCRGIDSRHWNSYCTTTQSFVKALTKEGNQASWRFIRIDTACVCVISRKTGNF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor 1, v-NGF-1, vNGF-1.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_CAMJJ
Sequence: MKNKLDLSLYLVASQGNKSEECFLNTLENAIKGGVSIIQLREKELNAREFYKLGLKVQKLCKAYKIPFLINDRVDIALALDADGVHLGQEDLEVKLARKLLGDEKIIGLSLKKLEQLEFIQGANYLGCGAIKATPTKESSLLSLELLSQICDKSPIGVVAIGGVDKAVLDELKGINLSGVAVVRAIMDAKDAFLAAKELKRKIYENLPLK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: GL_EHV1B
Sequence: MYQILIGCVWQKSPYINQCTEFQPPLSFVTPERMRRFMRCWARLELVYMLAWIVTTKLVKATRLDFTWGPGEPKRILEASCGSGPIMKGQLFTSPNIKNLLNRTTGIMVKAHCNPPEAILWVDTPPKPVWVNPFAVVQGLAEDVTNGNMPQDFKEKLLFALDDSLSQSQSSPDEILGPPPLGCFTGPFFLSPPKSKDIAEGLKDSCIPASYYANLQKT
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: HRD3_ORYSJ
Sequence: MQNRRRSRPVVPTPMARVRHRHLLLLVAAVAAAASALLPCASAVRPFVLVLSRDDFLKDTAGAHPSLPSADADSDEWDDFDDESPATDPLLSPSSWVPLLDPASASPSGDEPDSPSDALFVAGVRAMLSAASAGDDAAFATAAAQIEAAATGGHPGAQSALAFLSGAGMTRPASRSRAFLLHKFAADAGDLQSKMALAYSFFRQEMYEEAVTLYAELAEAALTSSLISKEPPVIEPVRLHSGTEENKEALRKSRGEDDEDFQITEYQAQRGNTVAMHKLGLLYYYGLRGVRRDYGKAYHWFSKAVEKGDTRAMELLGEIYARGAGVERNYTEAYKWLTLAAKQQQYSAYNGLGYLYVKGYGVEKKNLTKAKEFFEIAAEHKEHGGYYNLGVLYLKGIGVKRDVMTACNFFLRAVNAGQPKAIYQVAKLFQKGVGLKRNLQMAAVMYKSVAERGPWSSLSRWALESYLKGDIGKALLLYSRMADLGYEVAQSNAAWILDRYGDESICMGESGFCTDMERHLRAHALWWQASEQGNEHAALLIGDAYYYGRGVGRDYERAAEAYMHAQSQSNAQAMFNLGYMHEHGHGLPLDLHLAKRYYDQAVEVDPAAKLPVMLALTSLWIRKNYDGSFLVHFIDSLPEVYPVVEEWVEDVLMDEGNATIFTLFACLVTVLYLRERQRRQAAAANPQQPDGAPI
What is the function of this protein?
Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Functions as an ERAD substrate-recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex.
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase component HRD3, OsSel1.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MAND1_CAUSK
Sequence: MLKIIDAKVIVTCPGRNFVTLKITTSDGVTGVGDATLNGRELAVVSYLRDHMIPCLIGRDAHRIEDVWQFFYRGSYWRGGPVAMTALAAVDMALWDIKAKLAGMPLYQLLGGACREGVMVYGHANGETIEDTIAEARKYQALGYKAIRLQSGVPGLPSTYGVSGDKMFYEPADGNLPTENVWSTSKYLKHAPKLFEAAREALGDDVHLLHDVHHRLTPIEAGRLGKDLEPYRLFWLEDAVPAENQAGFRLIRQHTTTPLAVGEIFSHVWDCKQLIEEQLIDYLRATVLHAGGITNLRKIAAFADLHHVRTGCHGATDLSPITMAAALHFDLSVSNFGLQEYMRHTPETDAVFPHAYSYKDGMLHPGEAPGLGVDIDEALAGQYPYKRAYLPVNRLEDGTMYNW
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-mannonate dehydratase Caul1427, ManD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: EA22_LAMBD
Sequence: MSEINSQALREAAEQAMHDDWGFDADLFHELVTPSIVLELLDERERNQQYIKRRDQENEDIALTVGKLRVELETAKSKLNEQREYYEGVISDGSKRIAKLESNEVREDGNQFLVVRHPGKTPVIKHCTGDLEEFLRQLIEQDPLVTIDIITHRYYGVGGQWVQDAGEYLHMMSDAGIRIKGE
What are the official names of this protein?
Protein ea22.
Protein: PKS2_RUBID
Sequence: MVTVDEVRKAQRAEGPATILAIGTATPPNCVDQSTYPDYYFRITKSEHRTELKEKFQRMCDKSRIKKRYMYLTEEILKENPSMCEYMAPSLDARQDMVVVEIPKLGKEAATKAIKEWGQLKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLAVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGSDPLPDIERPLFELVSAAQTILPDSDGAIDGHLHEVGLTFHLLKDVPGLISKNIEKSLNEAFKPLDITDWNSLFWIAHPGGPAILDQVEAKLGLKPEKLEATRNILSEYGNMSSACVLLILDEVRRKSVANGHKTTGEGLEWGVLFGFGPGLTVETVVLHSVAAST
What are the official names of this protein?
Inactive polyketide synthase 2, RiPKS2, Inactive naringenin-chalcone synthase PKS2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: EF2_METTP
Sequence: MGKRKKIAERVVALMDKPERIRNIGIVAHIDHGKTTLSDNLLAGAGMISMELAGKQLFMDFDPLEQARGITIDAANVSMVHEYEGKEYLINMIDTPGHVDFGGDVTRAMRAVDGAVVVVDAVEGAMPQTETVLRQALREGVRPVLFVNKVDRMINELKVEKKEMAIRLGRVIDNINKLIRSMDEEHYKAGWRLDAANGSVAFGSALYNWAISVPQMKRTGIGFDQVYDYCRSDRMKELSQKCPLYVAVNDMIIRFLPSPLEAQKNRIRVIWKGDWNSPVGKAMTACDPNGPVAFMVTKIKVDPHAGEVATGRLFSGTLVRGMELHISGVPHTNRIQQTGIMMGAERIEVERIPAGNIAAVTGLRDAIVGSTVSSDPNMTPFEIIKHVSEPVMTVAVEAKNMRDLPKLIEVLRQTAKEDPTLQITINEETGEHLMAGMGELHLEIVATRIQRDKGVEIKTSPPIVVYRESVTGKSGPVEGKSPNHHNRFYIEIEPLEPGVIEVLKDGKIDMKMEEVERRKILIEAGMDKEEARNMVNFVGTNMFLNMTKGIQYLRETMELILEGFEEAITAGPICREPVQGIKAKLVDVKLHEDAVHRGPAQVIPAVRQAVQAGILMANPTLLEPMQYVFIQVPQDQMGGAMSEIQGRRGVILSMETEGDMITIKAKMPVAEMFGFAGAIRSATEGRALWSTEFAGFEPIPANMMLDTVRQIRTRKGLKPEMPTPSDYLKA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_YERPG
Sequence: MLKKILPVLITLAIVHNTPTAWAAEAPKTDSFYLPKSLDLSPLRLHNIESNPYGKDFNYAQQFKTLDLEAVKKDIKTVLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRIYDGRGGADGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGAKISWGDLMVLTGNVALESMGFKTLGFAGGREDDWQSDLVYWGAGNKMLSDNRDKNGKLPKPLAATQMGLIYVNPEGPNGKPDPVAAAKDIREAFARMAMNDEETVALIAGGHTFGKAHGAASPEKCLGAAPGEAGLEQQGLGWANKCGSGNGKDTITSGLEGAWTTDPTHFTMQYLSNLYKHEWVLTKSPAGAWQWKPKNAANVVPDATDPTKFHPLMMFTTDIALKVDPEYKKITTRFLENPEEFKMAFARAWFKLTHRDMGPAARYLGDEVPKETFIWQDPLPAANYKMIDSADISELKDKILKTGLSDTKLIKTAWASASTFRGTDFRGGDNGARIRLAPQKDWPVNDPAELHSVLAALMEVQNNFNKDRSDGKKVSLSDLIVLGGNAAIEDAAKKAGYSISIPFTPGRTDASQEETDVSSFAVLEPTADGFRNYYDAKRNTLSPIASLIDRANKLELTVPEMTVLIGGLRVLDVNSGGSKAGVLTNTPGQLNNNFFVNLLDMSTKWTKSPKAEGYFDGYDRKTGKLKWTASSVDLVFGSNPELRAVAEVYASDDAKEKFVHDFTKVWEKVMNLDRFDIKNN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ETF2_VACCA
Sequence: MRYIVSPQLVLQVGKGQEVERALYLTPYDYIDEKSPIYYFLRSHLNIQQPEIVKRHILLTLRMTQLKGYLGNLLDIKDDIIIYSHKNNLEYSYVDNTIFNPFVYTQKKTLLKNDSFLYNVYPGACDFLVIWVARACDTSIPEFGSYEDVDNNIIKFETMLMEVFPQLDLDITVESKFNNIFRTNLKLTGLKKIIQRVQDLDINYKSLLSRYDEHFINMTGNHFILNDEQLNLSIWDLDGTLALSSDGDTVMINNVKLFTDLVSDIDTQMERIKGDITYKVHLATPINSRIKLDIETSFIFIETATNNILLSSDKKISIILAKNHISIKVKNHIPNIEKYFTFLVIAINAMFNSVQKSADFTKVETVYWSRICQNTKNKNRKPIIINYLDPGMKKISNNFYRSDEKEVFINDNGIMFTCMDPLGKYNKVGFLNIFHDMWKYCIPCCFLHDQSHRSTFSSCVHQIDVEKKIVSPYILNFGKVVTESKMSFLPIIFDAFLNDGMTANMEQDNKRLKETSGYHIVRCCAGDDIVRLRTTSDIIQFVNEDKNILIVNDMVYFPMNASDIGKKIHILIQEIVHEVMIVKKKESSDKIDFFPPNYKLLKDLFPKQTIQTPIQSDAGMVLTTDGFYIDGKLFNEDLSSKYVTFTKNVIASDAVAKYFSPLFKYVISEAKDRFIKTWMINIMIHMNVDPNNIIPTLEKYYPNSGRAQIN
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa RAP94/OPG109 to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters.
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit, VETF A7 subunit, Vaccinia virus early transcription factor large subunit, VETF large subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
Protein: ERPA_XANCP
Sequence: MSTLVSLPTAAPAPDYQSIDRPLNFSNAAAAKVRELIQEEGNAELALRVYIQGGGCSGFQYGFEFDENRAEDDLAVATDGVTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NEK11_HUMAN
Sequence: MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL
What is the function of this protein?
Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage.  Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
What are the official names of this protein?
Serine/threonine-protein kinase Nek11, Never in mitosis A-related kinase 11, NimA-related protein kinase 11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase (PubMed:12154088). Accumulates in the nucleolus in G1/S-arrested cells (PubMed:15161910).
Protein: RPOZ_DESVM
Sequence: MARITVEDCQERVDNRFLLVQMAIKRVHQYREGYEALVDSRNKEVVTALREIAAGKVLPDEEARYVETEEDFRAE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL3_TROWT
Sequence: MARALLGTKVGMTQIWSGRRVVPVTAVAVTTNVVSQVKAPEKDGYSRLQIATGAIDPRRVNRPRKGHFAKAGLTPRRFIREVDSEGSLGDEFGPEIFQEGQLVDVVGKSKGKGFSGTMKRHNFQGVSATHGSHRNHRKPGSVGASSTPSRVFKGTRMAGRLGSSRVTVHNLRLVKIDSENGLLLVEGAVPGSSGSPVIIRDAVKGVPIVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SWC7_ASHGO
Sequence: MEYKYNVTLLLLQVVLHRQQELAHQDKTLSQISLLREPVVDTAVLERFSAHRVVRLYAPELCGLRLEELQAVVREVFARGLAGSAEDTPVTLITLANHYYRLRVQELELQELPKLKELMESAAGLRT
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
SWR1-complex protein 7.
What is the protein family that this protein belongs to?
Belongs to the SWC7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_SYNC1
Sequence: MTQQTVLDKIRSLVLPVLEEKGRELVDVEYRREGQGWILRLYIDQPGGVTLDACAEVSREVGVLLEVEDPIDTAYNLEVSSPGLDRPLTKLEDYERFAGRLAKVKSRVSIDVDGKGRGRKTFVGVLAGLSEGKVVLELKDKNGFRMEIPFEDIEKANLEIEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_PHLSQ
Sequence: KIAVERDPVKTSFEKWAQPGHFSRTLAKGPSTTTWIWNLHADAHDFDSHTNDLEDISRKVFSAHFGQLAIIFIWLSGMYFHGARFSNYEAWLSDPTHVKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQIWRASGITSELQLYSTAIGGLIFAALMLFAGWFHYHKAAPKLTWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQLLDAGVDAKEIPLPHEFILNRDLMTQLYPSFAKGLTPFFTLNWSEYSDFSTFRGGLNPVTGGLWLTDTVHHHLAIAVLFLIAGHMYRTNWGIGHSLKEILEAHKGPFTGEGHKGLYEIFTTSWHAQLALNLAMLGSLTIIVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLVVGAAAHAAIFMVRDYDPTTQYNNLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWVQNTHAVAPFSTAPNAAASTSLTWGGIDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSVSDQKIVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIVQGRAE
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYR_MICLC
Sequence: MKPEDLSALLSAVLTDAVDAGDLPAALREGITPARVKVERPRSREHGDWATNVALQLGKKAGMAPRDLAGLVAERLTGKPGIAAVDVAGPGFLNVTLDAASAGALAREIVEAGPEYGRNDTLAGHTVNMEFVSANPTGPLHIGHTRWAALGDAIARLLRASGADVTAEYYVNDAGNQMNVFADSVLARLHGRDVPAGGYPGAYVQELADAVALEHPDVRELTDEAARPVVREAAYRLQMQDIKDTLAAFDVHFDVFTSEQTLHDSGAIDQAVQRLREQGHIEDREGAVWLKTTDFGDDKDRVLIRANGEPTYFAADAAYYLHKRDRGFEEKVYLLGADHHGYVNRLKAIAAAAGDDPATNIEILIGQLISVNGAKLSKRAGNIIELKDLVEWLGRDALRYDLARYPADSPLTIDPELLRSATNDNPVYYVQYAHARASGAARTAQAHGVDRSEFDAALLTHATESELLAQLAEFPAVVAAAARLREPHRVTRHLEVIAGAYHSWYAACRIVPMPTDDGTPRPVETLNRTRLWLNDATAQVLANGLGLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCE_ACESD
Sequence: MEKLIITAAICGAEVTKEHNPNVPYTVEEIVREAKSAYDAGASVIHLHVREDDGTPTQSKERFKMCVDAIKEACPDAIIQPSTGGAVGMTDEERLQPVFLKPEMASLDCGTCNFGGDEIFVNTENMIINFSKYMIKNGVKPECEVFDKSMIDMAIRLAKKGHIQTPMHFNFVMGVNGGISATPRDLVFLIGSIPSESSFTVSAMGRNQFPMAAMAIITGGHVRVGFEDNVYIEKGVPAKSNGELVEKVVRLAKEFGRPVATPSEAREILGISK
What is the function of this protein?
Involved in the anaerobic fermentation of lysine.  Catalyzes the reversible reaction between 3-keto-5-aminohexanoate (KAH) and acetyl-CoA to form 3-aminobutyryl-CoA and acetoacetate.  The reaction involves the deprotonation of KAH, the nucleophilic addition onto acetyl-CoA and the intramolecular transfer of the CoA moiety.
What are the official names of this protein?
3-keto-5-aminohexanoate cleavage enzyme.
What is the protein family that this protein belongs to?
Belongs to the KCE family.
Protein: G6PI_SHEB5
Sequence: MTLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDLLFALASNSQLEAKIKAMFAGEIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTSKAITDIVSIGIGGSFLGPKIVSQALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVTSNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALSATEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGALIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLARIGASQDCDALDASSNALINLYRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_MAIZE
Sequence: MGISRDSMHKRRATGGKQKAWRKKRKYELGRQPANTKLSSNKTVRRVRVRGGNVKWRALRLDTGNYSWGSEAVTRKTRILDVVYNASNNELVRTQTLVKSAIVQVDAAPFKQWYLTHYGVDIGRKKKTPAAKKDNAEGQEVEAAAEETKKSNHVTRKLEKRKEGRTLDPHIEEQFGSGRLLACISSRPGQCGRADGYILEGKELEFYMKKLQRKKGKSAVA
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: RL16_MYCTO
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTTVNFGDYGIQALEHAYVTNRQIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPNEGVARAALTRAIHKLPIKARIITREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL21_ACIB5
Sequence: MYAVIQSGGKQHRVVEGETLKVELLKAESGATITFDDVLMVVNGDNIQIGAPVVAGAKVTAEVIGHGRHDKIRIIKMRRRKHYRKQQGHRQWFTELKITGISG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: LIGI_COMTE
Sequence: MSQFEKTPGWLDWYANPSKPQFKLPAGAVDAHCHVFGPGNEFPFAPERKYTPCDASKAQLYALRDHLGFARNVVVQATCHGADNRAMVDACKSSGGKARGVATVKRSISDAELQQLHDAGVRGVRFNFVKRLVDFTPKDELMEIAGRIAKLGWHVVIYFEAVDLPELWDFFTALPTTVVVDHMGRPDVTKGVDSEEFALFLKFMREHQNVWSKVSCPERLSVTGPKALNGEQNAYRDVVPFARRVVEEFPDRVLWGTDWPHPNLKDHMPDDGLLVDFIPHIAPTAELQQKLLVDNPMRLYWPEEV
What is the function of this protein?
Involved in the degradation of aromatic compounds via the protocatechuate 4,5-cleavage pathway (PubMed:11495993).  Catalyzes the hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to oxalomesaconate (OMA) (PubMed:7142106).  Also catalyzes the reverse reaction (PubMed:7142106).
What are the official names of this protein?
2-pyrone-4,6-dicarbaxylate hydrolase, PDC hydrolase, 2-pyrone-4,6-dicarboxylate lactonase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. PDC hydrolase family.
Protein: DTD_BIFAA
Sequence: MRIVLQKVSEGSVDVVDETSGEVDTTFEPQHIGIGYVLLVGVEDTDGAKQIDWLAHKIANLRVFEDENGKMNRSIHDVDGSVLSISQFTLYADVRKGNRPSFVKAGAPDHAEQVWHAFNDALRAQGLDVKEGRFGAHMRVSLTNDGPVTIIFDTDELGI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRP5_RHOPR
Sequence: APACVGFQGMR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 5, Rhopr-TRP-5.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_USTMA
Sequence: MAPKTLYEKIFDSHLVHEEADGTCLIYIDRHLVHEVTSPQAFEGLRNANRKVRRTDCTLATVDHNIPTASRKSYRDTKSFVEQVDSRTQCMTLEENVKAFGLTFFGLSDNRQGIVHIIGPEQGFTLPGATIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLQKRAKNMLIQVDGELSQGVTSKDIILHIIGLIGTAGGTGHVIEYAGSTIRSLSMEARMSICNMSIEAGARAGLIAPDEITYEYIKGRPLAPKQGEAWDQALAYWKTLPSDEGAQYDTVIKIDAKDIPPTVTWGTSPQDVVAITGTVPDPKNASNEAEAKAWTRALEYMGLEAGTPMEKIKIDKVFIGSCTNARIEDLRAAARVLHGRKVADGLYCMLVPGSGLVKKQAEAEGLDKIFQAAGFDWREAGCSMCLGMNPDQLAPGERCASTSNRNFEGRQGAGGRTHLMSPAMAAACAVTGYLTDVRKVVGHSSAKVGSDAAKPAFEIEVSDAKSYLVDATPAPAPTNVAAAGAGALTDEDALRDVPASHISSSGGGMEKFTTLTGIAAPLERSNVDTDLIIPKQFLKTIKRTGLGSALFWPLRYDAKTGEPDPAFVLNQKPYDQSKILVVTGPNFGCGSSREHAAWSLLDFGIRAVIAESFGDIFRNNLTKNGQLPVVLSRAQIQRLTQDAKAGKQITVDLVDQLVITADGKEKFSFETPEFTRHCLINGLDDIALTLQRDAQIGAFERNRSTHTPWLDGFGYHANSNSSSLLDSAKPLVNNVTATDW
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: APC15_XENTR
Sequence: MSTLFPSLFPQVTDSLWFNLDRPCVDENELQQQEQQHQAWLQSIAEKDNGLVPIGKPASEPYDEEEEEDDEDDEDSEEDSEDDEDMQDMDEMNDYNESPDDGEIEADMEGAEQDQDQWMI
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 15, APC15.
What is the protein family that this protein belongs to?
Belongs to the APC15 family.