PharMolix/UniProtQA huggingface dataset:
Protein: THI74_YEAST
Sequence: MNRVGIDVDHMIGVLLLAVVVVFWVGASCLTNELLETNAYNKPFFLTYLNISSFALYLTPDLWRIIQSRRKSLQERTERTLPIHTQESFSEFLPLLSSTPSTSSNLSSIADTKVKDTMRLSLLFCVLWFVANLAANAALSYTTVASSTILSSTSSFFTLFLATSLGIETFSTKKLLGLFVSLFGIILIVMQSSKQQDSVSASSFLVGNTLALLGSLGYSVYTTLLKYEISSKGLRLDIQMFLGYVGIFTFLLFWPILIILDITHMETFELPSNFHISFLVMLNCIIIFVSDYFWCKALILTSPLVVTVALTFTIPLAMFADFVWREAFFTPWYIIGVIFIFVSFFLVNHRGESAVEKDCAAVEKGPILDA
What is the function of this protein?
May be involved in thiaminediphosphate transport across the mitochondrial membrane.
What are the official names of this protein?
Thiamine-repressible mitochondrial transport protein THI74.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RS2_ECO55
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: BIOB_GEOTN
Sequence: MPNWLSLAEQVMEGYELADEEALAILDCPDDELLLLLQGAYRIRSVYYGNKVKLNMIMNAKSGLCPENCGYCSQSAVATAPVKTYKMLDKETLLRGAEEAYRLQIGTYCIVASGRGPSDKEVDIVVSAVKEIKERFGLKVCACLGLLKPEQAARLKEAGVDRYNHNINTSKQHHPNITTSHTYDDRVRTVETVKEAGLSPCSGVIIGMKETKQDIVDMARSLRELDADSIPVNFLHAIDGTPLAGTNELNPRYCLKVLALFRYMNPTKEIRIAGGREVNLRSLQPLGLYAANSIFVGDYLTTLGQEKSADYKMLEDLGFEIEFSPAPQIGVV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RNZ_PARD8
Sequence: MADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQVQMRRMRIKFSRLNHIFISHLHGDHCFGLPGLISTLGMLGRNGELVIHGPKEIESYMRPVLDIFCKGLPYEIRFNLIDPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAHIIREMTDFYQVPVRMMQEIKRGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHPSIIPIIEGVDLLYHEATFAECDAARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARYEDMAPLKKEADKIFPGTILGEEGMRLSV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: YL014_HUMAN
Sequence: MARVHIWPQHTAVNPRLLENQARAMIHHHLMAATPAVFLVSSGPDGSQAKAAAASYLAEPPGSPTPGPFSYTKASVVLFLPNPRPNIFKLHSKEQLAECHQYLQSNMRWDFSFAIKTRMLFLPCSDNV
What are the official names of this protein?
Putative uncharacterized protein FLJ43343.
Protein: SELO_ECO5E
Sequence: MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVEPGAMLMRVAPSHLRFGHFEHFYYRREPDKVRQLADFAIRHYWSHLEDDEDKYRLWFNDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLNDYEPGFICNHSDHQGRYSFDNQPAVALWILQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ATLA1_HUMAN
Sequence: MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM
What is the function of this protein?
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes.  Functions in endoplasmic reticulum tubular network biogenesis (PubMed:27619977).  May also regulate Golgi biogenesis.  May regulate axonal development.
What are the official names of this protein?
Atlastin-1, Brain-specific GTP-binding protein, GTP-binding protein 3, GBP-3, hGBP3, Guanine nucleotide-binding protein 3, Spastic paraplegia 3 protein A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon. Note=Localizes to endoplasmic reticulum tubular network (PubMed:27619977).
Protein: TJB21_HUMAN
Sequence: SYNEQFFGPGTRLTVL
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta joining 2-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: DCD_NITSB
Sequence: MGLKADCWIRQKAVEDGMIEPFCEDQIGKGVVSYGLSSYGYDIRVSDEFKIFTNVNAEVVDPKHFDERNVVDFKGDVCIVPPNSFALARTVEYFRIPRNVLAICVGKSTYARCGIIVNVTPFEPEFEGHITIEISNTTPLPAKIYANEGIAQVLFFEGDEDCEVSYKDKRGKYQHQRGITLPKIL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: GLYA_CLAM3
Sequence: MPVDQSFNAPLSEVDPEIAAVLEQELGRQRGTLEMIASENFVPRAVLQSQGSVLTNKYAEGYPGRRYYGGCEFVDVAEQLAIDRAKSLFGAEFANVQPHSGATANAAVLAAIAQPGDMILGLELAHGGHLTHGMKLNFSGKLYDAAAYGVDPDTFLIDMDVVREKALAHRPQVIIAGWSAYPRHLDFAAFRSIADEVGAKLWVDMAHFAGLVAAGVHPSPVPYADVVSSTVHKTLAGPRSGVILSRDTALAKKLNSAVFPGQQGGPLMHVIAAKATAFKIAATEEFADRQRRTIQGAQILAERLVAADSTEAGVSVLTGGTDVHLVLADLRNSPIDGKQAEDALHEVGITVNRNSVPFDPRPPMVTSGVRIGTSALATRGFGETEFTEVADIIAETLKPDSDLAALRARVLTLTDGFPLYEGLTQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_BDEBA
Sequence: MASSKFEEVRDKVKEFPTQSGVYLMKNTADKIIYIGKAKNLRNRVRSYFNDSKDHSPKTRLLVSNICEVEYILTKTEVEAFLLEASLIKKHRPKYNIRLRDDKAYPYIRFSWGDQAPRLYLARKVKKDGSLYFGPYTSGLAVHGTIKFLNRTFKIRDCTDAVFKSRTRPCMTYQIGRCTAPCVKYITMEDYRNEVEGAKLFLKGQNKKVIKSMTEKMMGAADEEKFEVAARLRDSIEAIKAILQKQAVINDTSEKDQDALGYYGDERGCLIETVHIRAGRVIGTRPHYLPHFDPNDAVEDPREWLVDFLNQYYEDNFIPDEVLLPLDIGNDLTKLMEEVLKERSGSKTTVRFATDERGRNLVDMAHENAKSHFLKYVSKSEEKLRGLEEIKERFNLPERPRRIECYDISTFQGAETVASQVVFEDGVPAKEHYRRYKIKTVQGINDFASMYEVLSRRFKHTEYDDPQLIVIDGGKGQLSQAMKILEEIGRKDIPVVGLAKARTESDFQKQEVESTEERFFLPGRSNPVIFKHNAEALYILSGIRDEAHRFAITYHRKLREGTSLESELDYVVGLGEKRKKVLLTQFNSIDEIKMADPEEIAKLKGFNRVLAERILLQLNESEEEETEVEE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYADM_MOUSE
Sequence: MPVTVTRTTITTTTSSSTTVGSARALTQPLGLLRLLQLISTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIVELGGLQAHFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQFLAHGRTRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPLLYNQKPALEWCVAVYAICFILAGVTILLNLGDCTNVLPIPFPTFLSGLALLSVLFYATAIVLWPLYQFDQRYQGQPRRSMDPSCTRSISYIQPNTVCFWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV
What are the official names of this protein?
Myeloid-associated differentiation marker, Myeloid up-regulated protein.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CNRG_CAVPO
Sequence: MNLELPKAEIRSATRVVGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones (By similarity).
What are the official names of this protein?
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.
Protein: SYP_SALPC
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAAKDSKSTLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGEGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGKKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPRR_PSEAE
Sequence: MIKRNLNDLLSFVAVAREGTFTRAAAQLGVTQSALSQSISGLEARLQIRLLTRTTRSVSPTAAGERLLNAIGNRFDEIEAELDELSALRDKPSGTVRITCGDHIQRTLLLPRLTPLLLEYPDIKVEFDINYGFRDIVADRFDAGVRLGDTIDKDMIAVPIGPPVRMAVVAAPAYFAAHPKPRSPRDLVDHNCINMRMQSGGGLYAWDFQRKDRHVNVRVDGQLIFNTSPNIVDAALAGLGIAWLPEEEFAPHIEEGRLLRVLENWCPLFPGYYLYYPNRRQPSPAFSLVVDALRYTRPRGTTIGGG
What is the function of this protein?
May have a role in the regulation of oprD expression.
What are the official names of this protein?
Putative transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SERC_SHIDS
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLHVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3528_NOSP7
Sequence: MQKKVKVKPNSKQQKIEEQPDGSLTVYLKSPPVDGKANEELIKLLAKKFDVAKSDIRIKSGLSSRQKLIEIDRDV
What are the official names of this protein?
UPF0235 protein Npun_R3528.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: PA2HB_ATRNM
Sequence: NLYQLWKMILQETGKNAAPSYGFYGCNCGVGSRGKPKDATDRCCFVHKCCYKALTDCSPKTDSYSYSWKDKTIVCGKNNPCLKQECECDKAVAICLRDNLDTYNKNYKIYPKPLCKKADDC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity, but has myotoxic and cytolytic activities.
What are the official names of this protein?
Basic phospholipase A2 homolog, svPLA2 homolog, Myotoxin II.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CBPH_DICDI
Sequence: MSRIYEQIEKDVEKIIGQYDGDKNGEVTINEAIEFFKRMGSKYPEKCAIVLFKMYDLDNEGKISYDEIQEEIFKRYQDKVREDQIKQYFQDDIEAFLLRYDKNRDNRIDFKELEQCFESIGSDHPKENANHIFTEIDKNRDGYLTIAEIKNYCRNTIRSKPYYQS
What are the official names of this protein?
Calcium-binding protein H, Calcium-binding protein 8.
Protein: RLMH_ALKEH
Sequence: MRIRLISVGGRMPGWAAEGYREYAQRLGGGISLELVEIPLGRRGKGADPRRALDEEGRRMLKALGDEQVVALDVRGKAWDTPALARELDGWLHDGRDLALLVGGPDGLHPDCLARAERRWSLSPLTFPHMLVRVLLAEQLYRAWSLLQGHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_ROSCS
Sequence: MIASVRGTLIAVAADHVVIETGGIGWMIYAPRQVLAAPGDIGAEMRLFTCLIVREDALTLYGFKTVEQRQLFETLLSVTGVGPQAALNLLSSGTTDELRLAIATGDVARLARTPRIGKKLAERLVLELKGKLDIKGLPVAPGVSPAVAAVNAELSEMLVSLGFSSAEASTAIAALPPDAPLDLEERLRLALRYFGAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Y4808_BURM9
Sequence: MPSFDVVSEANMIEVKNAVEQSNKEISTRFDFKGSDARVEQKERELTLYADDDFKLGQVKDVLIGKMAKRNVDVRFLDYGKIEKIGGDKVKQVVTIKKGVSGDLAKKVVRIVKDSKIKVQASIQGDAVRVSGAKRDDLQSTIALLRKEVTDTPLDFNNFRD
What are the official names of this protein?
UPF0234 protein BMA10229_A2508.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: URK_ANOFW
Sequence: MRKKPVVIGVAGGSGSGKTTVTKAIYEHFQGHSILMLEQDFYYKDQSHLPFEERLKTNYDHPLAFDNDLLIEHIHKLLNYEPIDKPVYDYTLHTRSNEVIRVEPKDVIILEGILVLEDERLRNLMDIKVYVDTDADIRIIRRLLRDIKERGRTLESVIEQYVNVVRPMHNQFIEPTKRYADIIIPEGGHNHVAIDLMVTKIQTILEQNSIL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_SOLM1
Sequence: MVMTAEDKAQVIGEHKKHDGDTGSPEVQVALLTSRIVYLTGHFKSHPKDFHSRTGLLKLVGQRRKLLNYLKKTDVQRYRDLIAKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: VGE_BPG4
Sequence: MEHWTLSGILAFLLLLSLFLPSLLITFIPLTSKPPVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPETKILSVTLKQTSVNSYALKVSCKDL
What is the function of this protein?
E protein is responsible for host cell lysis.
What are the official names of this protein?
Lysis protein, E protein, GPE.
Protein: TGT_BLOFL
Sequence: MVFRVLQTDGDARVGKLTCHHGIIETPAFIPVGTYGVVKSVTSQEVAESGAQIILSNTFHLWLRPGLEIIKIHQNLHKFMNWMGPIITDSGGFQVFSLNKLRKITESGVYFKDPVNGSTIFLTPEKSMDIQYHLGSDIVLVFDECVSYPSTWEYIKNSVEISLNWAERSRLHFDKLHNSNMLFAIIQGGMYEELRNRSAQELINIKFDGYAIGGLSVGETPQERFRIVSYVCKIIPFDKPRYLMGVGKPQDLIEAVCLGVDMFDCVIPTRNARNGYLFTNNGVVRIRNAKYESDLDPIEEDCDCYTCQRYYSRSYLHYLDRCNESLGIRLNTIHNLRYYQRLMEEIRQSIRMKKLRKFVEAFNYKFNSVSTNNYLSNI
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: HVD34_HUMAN
Sequence: MKHLWFFLLLVAAPRWVLSQVQLQESGPGLVKPSQTLSLTCTVSGGSISSGDYYWSWIRQPPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 4-30-4.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: UBIB_YERPP
Sequence: MTPGELRRLYLIIRVFLSYGLDELIPNIRLTLPLRVGRHLFFWLSNRHKDKSLGERLRLALQELGPVWIKFGQMMSTRRDLFPPNIADQLALLQDRVASFDGALARKHIEIAMGGALETWFDDFDSQALASASIAQVHTARLKENGKEVVLKVIRPDILPIIKADVRLMYRLAGWVPKLLPDGRRLRPREVVREYEKTLLDELNLLREAANAIQLRRNFEDSPMLYIPEVYSDYCRESVLVMERIYGIPVSDIAALEDQGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPHDPLYIGIDCGIVGSLNKADKRYLAENFIAFFNRDYRRVAELHVDSGWVPRDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWTTAKPFLESWLRDQVGLPAVIRALKEKAPFWAEKFPELPELVYDSLQQHKLLQQSVEKLTIQIQGQQQRQGQSRYLFGVGATLLVSGTILFLADATEVSTGFIVAGALAWFIGWRRTC
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SCX27_TITSE
Sequence: MYNMVSLFIVAVLLLTYANVEGSDVTGGFPVNSNNCIYPCYSTQDEIQCEEFCEKLNGRLGYCRRDACYCEHLPESVKQITNSKTFDCSNGPWDLSTV
What is the function of this protein?
Putative sodium channel toxin.
What are the official names of this protein?
Putative sodium channel toxin Ts27, Putative NaTx, Tityustoxin-27.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_SALPA
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLNERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.