PharMolix/UniProtQA huggingface dataset:
Protein: AT2A3_CHICK
Sequence: MEAAHSVPVQDVLSRFGVAESCGLSPEQVRRNREKYGPNELPAEERKSLWELVLEQFEDLLVRILLMAAFLSFILAWFEEGEESTTAFVEPIVIIMILIANAVVGVWQERNAESAIEALKEYEPEMGKVIRADRSGVQRIRARDIVPGDIVEVAVGDKVPADIRIIEIRSTTLRVDQSILTGESMSVIKHADPIPDPRAVNQDKKNMLFSGTNIAAGKAVGIVIATGVYTEIGKIRNQMVETEPEKTPLQQKLDEFSQQLSKVIFLVCIAVWVINISHFSDPVHGGSWFRGAIYYFKTSVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIMEKVEGTQCSLHEFSITGSTYAPEGQILKDEKPVRCGQYDGLVELATICALCNDSSLDYNESKKVYEKVGEATETALTCLVEKMNVFDTDTSKLSKVERANACNSVIKHLMRKECTLEFSRDRKSMSVYCTPTGPGHNSAGSKMFVKGAPESVIERCTHVRVGTAKVPLTPPVREKILSQIRDWGMGTDTLRCLALATHDAPVQRETMQLHDSTTFTHYETNLTFVGCVGMLDPPRKEVTSSIEMCRKAGIRVIMITGDNKGTAVAICRRIGIFTESEDVAGKAYTGREFDELSPEAQRQACREARCFARVEPAHKSRIVEYLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFSTIVSAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDKLPRNPKEPLISGWLFFRYLAIGVYVGLATVGAATWWFLYDAEGPQVSFHQLRNFMRCTEDNPIFEGVNCEIFESRYPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNIWLLGAIVMSMALHFFILYVKPMPLIFQVTPLSWPQWVVVLKISLPVILLDEGLKYLSRNHLEGEEDKK
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.  Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen.  Contributes to calcium sequestration involved in muscular excitation/contraction.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, ChkSERCA3, SERCA3, SR Ca(2+)-ATPase 3, Calcium pump 3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIS1A_ARATH
Sequence: MSLLLPTNLQQYPSSSSFPSSTPILSPPPSTAFSVIVPRRRCLRLVTSCVSTVQSSVATNGSSPAPAPAAVVVERDQIRLGLPSKGRMAADAIDLLKDCQLFVKQVNPRQYVAQIPQLPNTEVWFQRPKDIVRKLLSGDLDLGIVGLDTLSEYGQENEDLIIVHEALNFGDCHLSIAIPNYGIFENINSLKELAQMPQWSEERPLRLATGFTYLGPKFMKENGIKHVVFSTADGALEAAPAMGIADAILDLVSSGITLKENNLKEIEGGVVLESQAALVASRRALNERKGALNTVHEILERLEAHLKADGQFTVVANMRGNSAQEVAERVLSQPSLSGLQGPTISPVYCTQNGKVSVDYYAIVICVPKKALYDSVKQLRAAGGSGVLVSPLTYIFDEDTPRWGQLLRNLGI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).
What are the official names of this protein?
ATP phosphoribosyltransferase 1, chloroplastic, ATP-PRTase 1, AtATP-PRT1.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_DEIGD
Sequence: MSQPLLALNWKMNKTPSEARAWAADLSSALTPGNAELAVLAPAIDLPVLAGALPAGVALGGQDVSRFAAGAYTGEISAAMLRDVGATYVIVGHSERRTYHAETDAVVAAKARQAQAAGLIPIVCVGESLDVRERGAQVDFTLDQLRGSTEGVGENLIVAYEPVWAIGTGKTATADDAEELAAAIREALAGLYTAEARSFRILYGGSVKPDNIASICAQPNVNGALVGGASLNVADVVAMSDALR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR6P1_HUMAN
Sequence: MRNLSGGHVEEFVLVGFPTTPPLQLLLFVLFFAIYLLTLLENALIVFTIWLAPSLHRPMYFFLGHLSFLELWYINVTIPRLLAAFLTQDGRVSYVGCMTQLYFFIALACTECVLLAVMAYDRYLAICGPLLYPSLMPSSLATRLAAASWGSGFFSSMMKLLFISQLSYCGPNIINHFFCDISPLLNLTCSDKEQAELVDFLLALVMILLPLLAVVSSYTAIIAAILRIPTSRGRHKAFSTCAAHLAVVVIYYSSTLFTYARPRAMYTFNHNKIISVLYTIIVPFFNPAIYCLRNKEVKEAFRKTVMGRCHYPRDVQD
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6P1, Olfactory receptor OR1-12.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PG193_VACCC
Sequence: MRYIIILAVLFINSIHAKITSYKFESVNFDSKIEWTGDGLYNISLKNYGIKTWQTMYTNVPEGTYDISAFPKNDFVSFWVKFEQGDYKVEEYCTGLCVEVKIGPPTVTLTEYDDHINLYIEHPYATRGSKKIPIYKRGDMCDIYLLYTANFTFGDSEEPVTYDIDDYDCTSTGCSIDFATTEKVCVTAQGATEGFLEKITPWSSEVCLTPKKNVYTCAIRSKEDVPNFKDKMARVIKRKFNKQSQSYLTKFLGSTSNDVTTFLSMLNLTKYS
What is the function of this protein?
Counteracts the antiviral effects of host IFN-gamma.  Acts as a soluble IFN-gamma receptor and thus inhibits the interaction between host IFN-gamma and its receptor.
What are the official names of this protein?
Soluble interferon gamma receptor OPG193, B8.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
Protein: NTRYL_RICTY
Sequence: MLSYLKQNLCFYLSSKILILALAISAIVSACTTFYVISLEAKNFSTIIGFLLIDLAIFLILGILLTQKFFSKNNDNDSSRLQNRIVIAFSLVAAIPTIIVSVFSVYFFNLSVKAWFDKKISTVLDQSVIVAETYIAEHKVQLKETALAVAEDLSDMYYDLIHNPALFTKTLNTEADMRSLDEAIVLNKSTNTIVANSYLSFSLSFATIPAHLIKKADLGEPVEVKSDPTKIRMLIKLKEYNDVYLLVGRLVDNKIIDHIDATNGAAAEYNSLKNEIDNIQIKFSIMFIFIALLLLFVAINFGVLFTAQIVKPIKKLVTATDKVKDGDLTVQVPENEVDKDEIGTLYVAFNRMIKQLSRQQRDLVIAQRAMAWSDVAKKVAHEIKNPLTPILLASERLLKKFSAEIKDKSEFESYLKMIIRHTNDIKNIVSEFVLFARLPAPKFTKSELVYLVKHIIEARKLLNDNIVYTCDSNVDQFDFMCDATQINQVMINVLKNAEESIEGQEFGRIDVILDIKDDFINVIVMDNGKGFPPELIGKATESYVTTSSKGMGVGLAIVKRIVEEHCGVLDIANREDKGAIIDIKFDLKELHLKVRRSCG
What is the function of this protein?
Member of the two-component regulatory system RT0603/RT0550.
What are the official names of this protein?
Putative sensor histidine kinase NtrY-like.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14Z_TREDE
Sequence: MATVAKINQANRKAKYPTRQYNRCKVCGRPRGYLRKFKMCRVCFRKLASEGQIPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL13_BURM9
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIVINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKCPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NAGB_CLOAB
Sequence: MKIVTVNDYDEMSKFAAKIIASQIILKENSVLGLATGGTPLGMYKELINLYNKENLNFSKVQTFNLDEYYGVSDDNPQSYHYYMKNNFFKFTNIKNENINILDGTTSDIENECKSYDNKILSSGGIDIQVLGIGENGHIGFNEPDINFEAKTHLVKLDEKTIEANSRFFNSKNEVPTSALSMGIKTIMQSKKILLLANGEKKAEAIFKMVNGKISPEVPASILQLHNDTTIIIDKAAAKML
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: QUEA_NITEU
Sequence: MLAIGIIRSMKTDDFDFHLPDELIAQFPLANRSDSRMLYVNGKHADLRDAAFRNLPDYLKRGDVIVLNNTRVVKARLSGVKSTGGKVEVMVERILDTHRARVLIRASHALVIGSTLLLENKITAQVEAREQDIYTLCFMHSLPLIELLDQFGHTPLPPYIGRNATVSDENRYQTVFAQESGAVAAPTAGLHFDETMLQTLRTLGVKIIYVTLHVGAGTFQPVRVQNIDQHVMHTEPYHIPTETVEAIQMCKSAGGSVLAVGTTSLRALESCMLTNDGTLVAGAGETNLFITPGFRFRIVDRLLTNFHLPRSTLLMLVSAFAGMETIRHAYRHAIDNHYRFFSYGDAMLIDSQP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_SHEFN
Sequence: MAIRIKLKPGRERSLERRHPWIFSNGIHNVNGGKPQAGDTVEVVAHDGHWLGRGAWSPESQIQVRIWTFDKEETIDADFFARRIKRAQAGRDDLIREQGLTGYRLIAAESDGLPGITIDRYANVLVCQLLSTGAEKWRDTIVEQLVLQYPDCAVYERSDVDSRKKEGLVPVVGLLHGELPAMPVIIEENGIKIAVDVVKGHKTGFYLDQRDNRAMAARFVKGKSVLNCFCYTGTFGLYAAKAGAASIENVDVSTLALQTARDNMAINNLNDDHVNYNEADVFKLLRQYRDEGKTFDVIVLDPPKFADNKSQLDGACRGYKDINMIAMQLLNPGGILLTFSCSGLMQSDLFQKVVADAALDAKREVQFIERMHQASDHPISSAFPEGYYLKGLVARVW
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_AETCR
Sequence: MTYFVLFLGLCFVLGSLAVASNPSPYYGVVGLVLASIAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWGVVGYGVGFVAVLMVGLIVGGFVGSLDFGVATVDSVGMFSVRLNFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: GLPB_SHIF8
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVADIHSGLESLRQQAPAHPYSLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRATWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLAPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: RNPA_LACLM
Sequence: MAIKKTYRVKRSKDFDQIFSAKHSFANKRFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNRIKRLLRHAVAEFKPYLVDEDFVIIARSGVETLSFEEVKKNLRHVLKLSKIYVDGEND
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: FZO1_YEAST
Sequence: MSEGKQQFKDSNKPHKDSTDQDDDAATIVPQTLTYSRNEGHFLGSNFHGVTDDRTTLFDGEEGRREDDLLPSLRSSNSKAHLISSQLSQWNYNNNRVLLKRSILKTQAFMDQLQEENNIRPIFIAANDEREKLHVLQLNIKLDGQYNTKEKNGFNIEKKALSKLFHSQIVSVTNHLNALKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQLPCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDLVPQNGKYALLKIYIKDDKRPASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEIDLVIFVVNAENQLTLSAKEFISLASREKKLMFFVVKKFDKIRDKQRCKELILKQIRDLSPETYKRAADFVHFVSKNGDELPHYHNENDNEDHGDRKPDDDPYSSSDPDPDFDSLEDSLRNFVLKKRSLSKLLPAKTYLSKLLSDIIMISKSNMKMYSEEEIKINEQLETLRPEILSARAKCNDLTTSVDQMAEQTITMTYNNTKEALLNALDVPLHEYPKYQGLGQIYDFIFSTEAFIANQIDESIGSSELFAKQKTDLLVKKIYEIGKNELGDDFMCERVFRSELMFRKRKHLIGKRLKVSLSITDLFAPTWKGFLSYLSWQKPVTAPLPDIEGQTNEGQIGLMKYLGLKNYPLTQYWSRPSLLFTSKIPTLTLYFLGSTKVVGNIILNGIKLSSWSSLKKLSVPVIVVGSLLGLTYLIHDLPRALPMNLSIKYKRKLQELDYIHLNAQRTSNEVRDVLRVPTREILRSCEIIMDKKQITKKELENKKESNLLSIKFFQSLYEGTVAQKLMVEEINLDID
What is the function of this protein?
Essential transmembrane GTPase, which mediates mitochondrial fusion (PubMed:9685359, PubMed:9786948, PubMed:10562274, PubMed:11266460, PubMed:15297626, PubMed:15760898, PubMed:16624808, PubMed:19812251, PubMed:21385840, PubMed:21502136, PubMed:23317502, PubMed:27253069).  Fusion proceeds through several steps; first mitochondria are tethered together, then brought into close contact, followed by the formation of a docking ring around contact areas, and finally membrane fusion (PubMed:27253069).  Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondrial morphology, which is balanced between fusion and fission, mediated by FZO1 and DNM1, respectively (PubMed:10562274).  Functions antagonistically with DNM1 (PubMed:10562274).  Probably acts by forming membrane contact sites that mediate mitochondrial membrane fusion (PubMed:27253069).  Mitochondrial docking and fusion requires GTP hydrolysis (PubMed:15297626, PubMed:19812251, PubMed:27253069).  Mitochondrial fusion promotes also increased lifespan.
What are the official names of this protein?
Mitofusin FZO1, Transmembrane GTPase FZO1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=Detected at the periphery of mitochondrial contact sites that form before mitochondrial fusion.
Protein: PRM10_ZYGRC
Sequence: MGKSDHLKLFGKKSGGKDARSPETRSRNSRSSTDNRSSIGNNGSDNPLARLSDLDLEEGVDDDADFDWDTLPLPPSDAQSLDNPFNSGEALPSFRRRGGPTSNDAIERDAVDTIRDTSGAYEEPDSASDGEDVGMNDEYQRKRERLVDVNDSASEVSSPRRESREGKNVRFHTETDDINPEDPIAAPAANTEAGTGTNENGEASSSGMKSSINVDDEEGSETSSSNNENKLDHFKKFFRRGSVQNKPDGGEDGAEKGMKSMKDDDNDDEKEGGGGFFSKVIQNIKDANNGLAPGLRNVNLHPEADPEKNSVQEAEVDGDDIQLVDFNSVAKGLVKNYSSLPQSAHHQKEPAILEGDTMYSPSTPSSSPGPESFVAAPMDDYDFDQVDSDGEDSDLDPFVGAQTYVPPPQRVRGGVLGSLLKMYQNEDVSDSFSTASSIGEEPAKPSKPLLDPHFSKGKIPTAGSLLHVPSSAASHLKKNAQQLAGGAHNLATKHYPGRKNEEASGSNSELPSFKNTRPKKNKKHLPKFKKKMAAEAKITVHIADLLQRHRFILRMCKGLMMYGAPTHRLEEYMIMTSRVLEIDGQFLYLPGCMIVSFGDATTRTSEVQLVRCAQGLNLWKLHQVHSIYKQVVHDTMSASEGNILMDKVLQDRNLVPSWVCVLLYGFCSAMVTPYAFGGDWVNLAVSFFIGTCVGALQFIVSARSNMYSNVFEISASIVVSFVGRAFGSIGGSKICFGAVTQGSLALILPGYIILCGALELQSRNLVAGSVRMFYAIIYSLFLSFGITLGAALFGWMYKNATNETNCPYPISPWYRFLFVPAFTIGISLINQAHWIQLPVMVTISCTGYVVTYYSGKHFKNSTEFTASLAAFVIGIMGNLYSRVWKGLAVSAMLPAIFVQVPSGVASQSSLLSGLQSANELIKTNSTKGGDAMPGASDLSGSLSFGITMIQVSIGITVGLFGSSLIVYPFGKKSTGLFSL
What are the official names of this protein?
Pheromone-regulated membrane protein 10.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SIDA2_COCH4
Sequence: MSPHVDMSSGSPDGAAPAVQKAFNGFLTENIDESQFPALENRSHLRYTPQDELHDMICVGFGPASLAIGVALHDALDGTDGSLADVQGLQSRPPKVAFLEKQPQFAWHAGMLLPGAKMQITFMKDMATMRNPRSEFTFLNYLHQKDRLVEFANLNTFLPARVEYEDYMKWCASWFEEVVAYSQEVVKVMPEKSASGEITSFNVMSHNHLTGRTESRRAKHVVIAAGGRPNIPAPFPTNHPRVIHSSQFSYMSKQLLKDHDAPYNIAVVGNGQSAAEIFDFLHANYPNSRTRLLIKGGALRPSDDSPFVNEIFNPSRTDCTYNRAPKLRATTLVEDKGTNYGVVRLGLLEHIYETLYMQRIRYGNSPAEEAHWPHRILPYRRVMDVTESPVCQGGVRLHVQDSSALYFSEQAGGQERKETLDVDAVFVATGYLRDLHETLLKDARHLMPGGELEGAKWQVQRDYRVNFTEKSVGEDAGVWLQGCCESTHGLSDTLLSVLATRGGEMVRSLFEKPAKWDNGHVLGGYEVRE
What is the function of this protein?
L-ornithine N(5)-monooxygenase; part of the gene cluster that mediates the biosynthesis of hydroxamate-containing siderophores that play a critical role in virulence (PubMed:23980626).  Cochliobolus heterostrophus produces extracellular coprogen-type siderophores including coprogen, neocoprogen I and neocoprogen II, as well as the intracellular siderophore ferricrocin (PubMed:17056706).  The role of extracellular siderophores is to supply iron to their producers in planta and the intracellular ferricrocin is required for intracellular iron distribution and storage with a crucial role in ascus and ascospore development (PubMed:17056706, PubMed:17601875).  SIDA2 catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores (PubMed:23980626).  The assembly of extracellular coprogen-type siderophores is then performed by the nonribosomal peptide synthetase (NRPS) NPS6 whereas the intracellular siderophore ferricrocin is assembled by NPS2 (PubMed:17056706, PubMed:17601875).
What are the official names of this protein?
L-ornithine N(5)-monooxygenase, OMO, L-ornithine N(5)-oxygenase, Siderophore biosynthesis cluster protein A2.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: GANR_BACSU
Sequence: MATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIAFLYWLTDKEELEDVYFKTMRLEVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFSDEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKTVNILTEKGHKSIGFIGGTYKNPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTAFMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAVQLLLEQVQDKRRTVKTLYVGAELIVRKSMN
What is the function of this protein?
Negatively regulates the expression of the ganSPQAB operon (PubMed:2104611, PubMed:9287030, PubMed:27501980).  Inhibits transcription of the operon by binding to an operator in the promoter region (PubMed:27501980).  In the presence of galactobiose, GanR dissociates from the promoter, resulting in the expression of the gan operon (PubMed:27501980).
What are the official names of this protein?
HTH-type transcriptional regulator GanR.
Protein: ENOD8_MEDTR
Sequence: MKFMAKIELSRHIPLVTLIVLVLCITPPIFATKNCDFPAIFSFGASNVDTGGLAAAFRAPPSPYGETYFHRSTGRFSDGRIILDFIARSFRLPYLSPYLNSLGSNFTHGANFASGGSTINIPKSILPNGKLSPFSLQIQYIQFKEFISKTKLIRDQGGVFATLIPKEDYFSKALYIFDIGQNDLTIGFFGNKTIQQVNATVPDIVNNYIENIKNIYNLGARSFWIHGTGPKGCAPVILANFPSAIKDSYGCAKQYNEVSQYFNFKLKEALAELRSNLSSAAITYVDIYTPKYSLFTNPEKYGFELPFVACCGYGGEYNIGVGCGASININGTKIVAGSCKNPSTRIIWDGVHYTEAANEIVFSQILTGVFNDPPISLDRACYRK
What is the function of this protein?
Has lipase and esterase activities (By similarity).  Probably involved in root nodule physiology (Probable).
What are the official names of this protein?
GDSL esterase/lipase ENOD8, Early nodule-specific protein 8.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
Protein: CLPS_DESAL
Sequence: MSPDPHEDLGDVLTEPTQKTERPRMFKVLLHNDDYTTMEFVVGVLQRVFNKSVPEATRIMLNVHNRGVGVAGVYTAEVAETKIETVHSMAQADGFPLKCSMEPE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: CDC45_MOUSE
Sequence: MFVTDFRKEFYETVHNQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAYLEHKEQFSYFILINCGANVDLLDILQPDEDSIFFVCDTHRPVNVVNVYNDTQIKLLIKQEDDLEVPAYDDIFRDEAEDEDLSDSDGDGSEPSEKRTRLEEEIVERNRKRRQRREWEARRKDILFDYEQYEYYGTSSAMVMFDLAWMMSKDLNDMLWWAIVGLTDQWVHDKITQMKYVTDVGILQRHVSRHNHRNEAEENMLSVDCTRISFEYDLCLVLYQHWSLHESLYNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQSMDVSLKGNLREMIEESANKFGMKDMRVQTFSIQFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYLGLELAKKHLQATQQTIASCLCTNLVTSQGPFLYCSLMEGTPDVTLFSKPASLSLLSRHLLKSFVYSTKNRRCKLLPLVMAAPLSVEQGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRTLHNYFDLSVIELKAEDRSKFLDALVSLLS
What is the function of this protein?
Required for initiation of chromosomal DNA replication.
What are the official names of this protein?
Cell division control protein 45 homolog, PORC-PI-1.
What is the protein family that this protein belongs to?
Belongs to the CDC45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCTA_XANCP
Sequence: MHISKPAGPLPAPVPFYRQLYFQVVVAIVLGALLGHFEPAFAESLKPLGDAFIKLVKMIIAPVIFLTIVTGIAGMTHLKTVGRVFAKSMTYFLFFSTLALIVGMVVAHVVQPGAGMNINPAELDQSAVNTYVQKSHELSLVGFLMDIIPATLISAFVDGNILQVLFVAVLFGIALALVGERGRPVLSFLEALTAPVFRLVHMLMKAAPIGAFGAIAFTIGKYGVESLVNLAWLVGSFYLTSLFFVLVILGIVCRLCGFSVLKLIRYLKAELLLVLGTSSSESALPSLMEKMEKAGCEKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNVDLTLGQQITLLAVAMLSSKGAAGVTGAGFITLAATLSVVPDVPVAGMALILGVDRFMSECRSLTNFIGNAVATVVVSRWENALDRDQLSLALDGRAPPLQAPVPPPDAVAPVSAR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_SYNY3
Sequence: MALSFSKYHGLGNDFILVDNRQSTEPCLTPDQAQQLCDRHFGIGADGVIFALPGQGGTDYTMRIFNSDGSEPEMCGNGIRCLAKFLADLEGVEEKTYRIHTLAGVITPQLLADGQVKVDMGEPQLLAELIPTTLAPAGEKVVDLPLAVAGQTWAVTCVSMGNPHCLTFVDDVDSLNLTEIGPLFEHHPQFSQRTNTEFIQVLGSDRLKMRVWERGAGITLACGTGACATVVAAVLTGRGDRRCTVELPGGNLEIEWSAQDNRLYMTGPAQRVFSGQAEI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHYK1_ARATH
Sequence: MAATLPLSPINHQLCRFGNNSLTTHRFCSPGFLISSPCFIGLTGMGSATQLRARRSLISSAVATNSLLHDVGATVAVLGGAYALVLSFESLTKRNVIQQSLSRKLVHILSGLLFVLAWPIFSGSTEARYFAAFVPLVNGLRLVINGLSISPNSMLIKSVTREGRAEELLKGPLFYVLALLFSAVFFWRESPIGMISLAMMCGGDGIADIMGRKFGSTKIPYNPRKSWAGSISMFIFGFFISIALLYYYSSLGYLHMNWETTLQRVAMVSMVATVVESLPITDQLDDNISVPLATILAAYLSFGY
What is the function of this protein?
Kinase involved in the activation and reutilization of phytol from chlorophyll degradation in plant metabolism, including tocopherol biosynthesis.  Catalyzes the conversion of phytol to phytol monophosphate (PMP) in the presence of CTP or UTP.  No activity with ATP or GTP as phosphoryl donor.
What are the official names of this protein?
Phytol kinase 1, chloroplastic, Vitamin E pathway gene 5 protein.
What is the protein family that this protein belongs to?
Belongs to the polyprenol kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: ATP11_YEAST
Sequence: MWRLTRKIGTRIHISNQLSPIFNKAIGTVPVFRFYSSSPEQKYRKKLLEEAQKQGFNSIEELKNHLKETIESKKREFNKIDPLKELEDYQQKTQMENNNSKHLMTKSRSPLDPSAPKVPFKTLDSFLDVGKLKDLSKQEVEFLWRARWAQKDNTLCAVIPVSVYDKMMANARNNPIFVLPLPRQVQSEDAKPNEEQGMELHYIQWQFVGPQTTHCMMTSLAEYKLHQEFARPHTTLQFHSDLVKDKGIVFMNGHVEPDTNVNVQDAQLLLLNVQRFYGAMGEETPVAKQRVQLLRDFSKASPGFTVEKLISLSQSMEN
What is the function of this protein?
Essential for the assembly of the mitochondrial F1-F0 complex.  May interact with the alpha and/or beta subunits of F1-ATPase.
What are the official names of this protein?
Protein ATP11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP11 family.
What are the subcellular locations of this protein?
Mitochondrion.