PharMolix/UniProtQA huggingface dataset:
Protein: KAD2_HUMAN
Sequence: MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Adenylate kinase 2, mitochondrial, AK 2, ATP-AMP transphosphorylase 2, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: HTF_PSEFO
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, PseFo-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_NEIMF
Sequence: MNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAKQNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGNTVIRQNHVGDWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFVDISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFRKAGEWDADAPTVLTEPLEKQLAAELLKFENVLQSVADTAYPHYLAAYLYQIATLFSRFYEACPILKAEGASRNSRLQLAKLTGDTLKQGLDLLGIDVLDVM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2723_EXISA
Sequence: MSQMDRTMQFNFPEDDQRANTRETLITVYQALEEKGYQPINQIVGYLLSGDPAYIPRHNDARNLIRKIERDELLEELVKSYLNDRRED
What are the official names of this protein?
UPF0297 protein EAT1b_2723.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: PDXB_SHESR
Sequence: MKIVVDENMPYVEPLFGALGEIIPVNGRTLTPEQVQDADVLLVRSVTRVNAALLDANPKLKFVGSATIGTDHVDLAYLAGRGIPFSNAPGCNATAVGEFAFIAMLELAARFNSPLKGKVVGIVGAGNTGSATAKCLEAYGIKVLLNDPIKAAEGDPRHFVSLETLLLEADIISLHVPITRSGEHKTLHLFDEARLMSLKPNIWLVNCCRGDVIDNQALIKVKKQRDDLKLVLDVWEGEPHPMPELVPFAEFATPHIAGYSLEGKARGTFMLYQKLCELLAIPANKRLSELLPPFHFKAVELEQTPDEKALLQLARFVYDLRDDDAVFRNGFARSNGFDTMRKNHKHRREFSALALAYHGQSEVDWLSNLGFSGVGR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGC2_RAT
Sequence: MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQEASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVNKTTNSKVAQASFKARLE
What is the function of this protein?
Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic, 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: DAPL1_HUMAN
Sequence: MANEVQDLLSPRKGGHPPAVKAGGMRISKKQEIGTLERHTKKTGFEKTSAIANVAKIQTLDALNDALEKLNYKFPATVHMAHQKPTPALEKVVPLKRIYIIQQPRKC
What is the function of this protein?
May play a role in the early stages of epithelial differentiation or in apoptosis.
What are the official names of this protein?
Death-associated protein-like 1, Early epithelial differentiation-associated protein.
Protein: SBIR1_ARATH
Sequence: MAVPTGSANLFLRPLILAVLSFLLLSSFVSSVEWLDIDSSDLKALQVIETELGVNSQRSSASDVNPCGRRGVFCERRHSATTGEYVLRVTRLVYRSRSLTGTISPVIGMLSELKELTLSNNQLVNAVPVDILSCKQLEVLDLRKNRFSGQIPGNFSSLSRLRILDLSSNKLSGNLNFLKNLRNLENLSVANNLFSGKIPEQIVSFHNLRFFDFSGNRYLEGPAPVMSSIKLQTSPHQTRHILAETPTSSPTNKPNNSTTSKAPKGAPKPGKLKKKKKKSKKKKVAAWILGFVVGAIGGTISGFVFSVLFKLIIQAIRGSEKPPGPSIFSPLIKKAEDLAFLENEEALASLEIIGRGGCGEVFKAELPGSNGKIIAVKKVIQPPKDADELTDEDSKFLNKKMRQIRSEINTVGHIRHRNLLPLLAHVSRPECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRIIHRDLKPANVLLDDDMEARISDFGLAKAMPDAVTHITTSHVAGTVGYIAPEFYQTHKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNIITSENPSLAIDPKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIKH
What is the function of this protein?
Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates.  Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death (PubMed:19616764).  Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity (PubMed:27251392).  Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission (PubMed:20081191).
What are the official names of this protein?
Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1, Protein EVERSHED, Protein SUPPRESSOR OF BIR1-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL29_ALISL
Sequence: MKAQDLREKNVEELNEELLNLLREQFNLRMQAATGQLQQTHTLKAVRRDIARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UNG_FRASN
Sequence: MPAQPLRDILEPGWAKALEPMADRIAAMGDFLRAEIAAGRSYLPAGQHVLRAFQQPFDDVRVLIVGQDPYPTPGMAIGYSFAVAPEVRRLPGSLENIFQELCADLSVPRPTNGDLTPWTRQGVLLLNRVLTTAPRQPGAHRGKGWEEVTEQAIRALAARGTPLVAILWGADARSLRPFLSPAPTIESAHPSPRSADRGFFGSRPFSRANNHLLEQGAQPVDWHLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_YERPB
Sequence: MTNIIRQFLRQEAAGGLILIIAAAIALLMANSALQGVYQSFLDIPVSIKIASLDISKPLLLWINDGLMAVFFLMVGLEVKRELMEGSLAGRDKAVFPAIAALGGMLAPALIYLLFNGADEVTRQGWAIPAATDIAFALGVMALLGNRVPTGLKVFLLALAIIDDLGVIIIIALFYTQQVSLQSLGIAAAAIALLAYMNWRGVGKTSAYLLVGLVLWVCILKSGVHATLAGVIVGFMIPLHTQDQRSPSESLEHGLHPWVAYLILPLFAFANAGVSLQGVSLSGLTSLLPMGIATGLFIGKPLGIFTFSWLAVKLGIAKLPDAINFKQIFAVSVLCGIGFTMSIFIASLAFEGTDIALTTYSKLGILLGSTTAAVVGYSLLRLVLPARRKAVNVR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF4_AGRST
Sequence: MNWRSEHVWVELLKGSRKRGNFFWACILFLGSLGFLSVGASSYLGKNIISILPSQQILFFPQGVVMSFYGIAGLFISSYLWCTILWNVGSGYDRFDRKEGIVCIFRWGFPGIKRRVFLQFLMRDIQSIRIQVKEGLYPRRILYMEIRGQGVIPLTRTDEKFFTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MATP_PHOLL
Sequence: MKYQQLENLECGWKWTYLMKKHQEGELITKYIENSAAHAAVDKLIELESEPVRVLKWIEQHMNPDLSNRMKQTIRARRKRHFNAEHQHTRKKSIDLDFPVWHRLSALSQRRGNTLSETIIQLIEDAERKEKYANQMSSLKHDLEAILGKKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSS1_ARCFU
Sequence: MFKRETKDFINIDPLQTGGKLTEEARQALLEWGDGYSVCDFCTTGRLDEIKTPPIHDFIHNQLPKFLGCDVARVTNGAREAKFAVMHSLAKKDAWVVMDENCHYSSYVAAERAGLNIALVPKTDYPDYAITPENFAQTIEETKKRGEVVLALITYPDGNYGNLPDVKKIAKVCSEYDVPLLVNGAYAIGRMPVSLKEIGADFIVGSGHKSMAASGPIGVMGMKEEWAEIVLRRSEKYKNKEVELLGCTARGATIITLMASFPHVRERIKRWDEEVEKARRFAAEMEKLGIKQLGDNPHNHDLMFFHAEVLYEISKKAKGGRFFLYRELKSRKIHGIKPGLTRYFKLSTYGLSDEEVDYVLNAFKEIIEKYS
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase 1, Sep-tRNA:Cys-tRNA synthase 1, SepCysS 1.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: Y188_STRPJ
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SPN23F01880.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RPOC_LEPBL
Sequence: MRSHNDFESITIRLASPERIKEWSYGEVKKPETINYRTLKPEKDGLFCEKIFGTTKDWECYCGKFKSIRYKGVICDKCGVEVTHSKVRRERMGHIELAAPVSHIWYYRSVPSRMGLLLDMTVNQLKSVLYFEKYVIIDPADSGRSRGELIDEEEYHGYLDEYGDKFVAGIGADAIKELLARIDVDAEARMIRQKIQDKDKISDKRILKRLEVLEAFRDSGNRPEWMVLDIVPVIPPELRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLALKAPEIIVRNEKRMLQEAVDALFDNSRRKRAVKGKGNRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKYHEMGLPKKMALELFKPFIMKRLVDLDLAPNIKSAKKKVEAEDKEVFDVLEYVVKEHPVMLNRAPTLHRLGIQAFLPVLVEGKAIKLHPLVCHAFNADFDGDQMAIHVPLTPKAQLETWMLMLSPHNILNPANGHPICGPTQDIVLGIYYLTSELPSEPGAPLKSFSNLDEVHYAIDRGVVEFRTKISVYHQGKILETTPGRLIFNTILPEGYAYVNRPLSDKETNRIIADVYDKYGPAKTVLMLDDIKKLGYRYATLFVPTISIEDIRVSPGKVGLVGDANKEVEKADSEYRKGIITNEERRKKVIEIWTKTNDLITESMFKELEKDKGGFNPVFIMAASGARGSKQQIRQLAGMRGLMAKPSGEIIELAIRSNFREGLSVLEFFISTHGARKGLADTALKTADAGYLTRRLVDISQDVIISEDDCGTEESISLGIVKEGENVIVSLNDRVFGRYTAEDVIDPVTDKVVYPRNTLITREVGQKVENLGYDKIRVRSPLTCESKQGVCIRCYGMDMARLIPAEIGEAVGTIAAQSIGQPGTQLTMRTFHIGGAASAKVQEKEHKVSYTGIVNNINGRLITNEKSQSVFSRRGSIVIQRLIQQYKTEELSNLRVENGQKVDKGELVATSPSGENITSAMPGAVHIENGIFRILGEEAVIPVKTGTVVNVKVNDITQPNQPLAEFDPYNEVGISEIDGTVQWMDLEIGKNVRRDEDLRTSNILLKVIEQRREKLNPRIAVISGGSREEYSVPVDAIISVQDGDKVKAGDILFKIPTVAEKTRDITGGLPRVDELFEARRPKDATTLAETDGKIEISGEIVKEKRVLYIHPDNPDQEKVKVTIPIGKQIRVRNGDFVKRGDQIDDGNLDPHDILRVKGVTALQVYLVQEVQEVYRLQGVHINDKHIEVVVRQMLRKVLITDSGDTSFVNQQQIDRLMFNEENKRVIAEGGSPAESVPILLGLTKASLNTESFFSAASFQETTKVLTDAAIKGKTDNLMGLKENVIIGHMIPAGTGTKKYKDISVFKSAYGDLDRPLEEEEEEEIPQSIADDSDGDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: VF143_IIV3
Sequence: MVYVISIEGIIGSGKSSLMDQLKRHYTCHQEPLHDWSLLQPFYDDMERYASPFQFQVLFSFHKLYSTIKNVNDVVILERCPWSSRNIFTKMLVQDGFISPQEYELYMSFYDRLAFTTNLHIYLKVDPTVAFDRILKRNREAEKTLQYDYLVRLNHQYEAEISKCDNVYVVDANKPMELVGNTVLRLLSRLCRR
What are the official names of this protein?
Putative kinase protein 029R.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
Protein: COAX_GLOVI
Sequence: MWLAVNIGNSRQHWGWFTGTKLVRTLDFPLTHWDAQAPDAAEQIVVASVTTTHLERWRTLPHARILNLADVPLSGTYPTLGIDRALNLIAAADAYGCPALVTDFGTAITLSAVDEFGRFCGGAILPGLGTQLRALEHFTAALPAVDLPEPWPPLLARTTQAAIQSGVVRVTLAGLAQFLESWKRQYPGGISVATGGDSERVHRWLPDLFDVQDTHLTLWGICVAARGAD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_BRUME
Sequence: MGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTGIGTLGVAITDDPLPVFAKAHGVLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKIRAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDIEILEMHHRHKVDAPSGTALLLGEAAARGRDIALADNSVRVRDGYTGPRETGTIGFATLRGGSVIGDHSVILADTGERVVLSHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSC6_ALTBR
Sequence: MAVQETDLDKQLLQLSIQVADLAARTDSRGSQKIQDFLIKTQQSLESPWETLMRYYDLDFQHVAIRIGCDMQVFTTLTTADKPMKLQDIANVNGASERLLGRVLRYLASINTIEEVGKDTFEANHITRTLSKPGIEGGIRLSSACQRPTNSALPDLLVERGFQDITSATETAFNKAWASREPFFTWVRSQPKIFEYLRLALDVQFREDWLNAFPLESHLGDFASRADPEKVLFVDVGGNLGIQCRGLKAKFPHLSGRIILEDLQETIDVALALEGVETLAQDYLTEQKVKGAKFYYYRNIFHDNPDDRCRLILDALKPAMEESSLLLIDDKVLLNQGSHRHVTMLDLAMMAQVASHERTRAQWQALLEGAGWKIEDIFQYSHEYDSIIVVKPAAQNA
What is the function of this protein?
16-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C (PubMed:19097780).  In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) that is further converted into fusicocca-2,10(14)-diene, the first precursor for brassicicene C (PubMed:19097780).  Fusicocca-2,10(14)-diene is then substrate of cytochrome P450 monooxygenase bsc1 for hydroxylation at the C-8 position (PubMed:19700326).  Oxidation at C-16 position to aldehyde is then catalyzed by the cytochrome P450 monooyxygenase bsc7, yielding fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:19700326).  Follows the isomerization of the double bond and reduction of aldehyde to alcohol catalyzed by the short-chain dehydrogenase/reductase bsc3 to yield the diol compound fusicocca-1,10(14)-diene-8 beta,16-diol (Probable).  The next step is the oxidation at the C-3 position of fusicocca-2,10(14)-diene-8-beta,16-diol catalyzed by the alpha-ketoglutarate dependent dioxygenase bsc9, to produce a triol compound (PubMed:21299202).  Methylation of the hydroxy group at position 16 is performed by the methyltransferase bsc6 (PubMed:19097780).  16-O-methylation is followed by oxidation at the C-13 position to ketone and an alkyl shift of the methyl group leads to brassicicene C (Probable).  Although the probable acetyltransferase bsc4 is included in the gene cluster, no acetylation reactions are necessary for brassicicene C biosynthesis.  However, the fact that brassicicene E, which is a structurally related compound having an acetoxy group at position 12, was previously isolated from another strain of A. brassicicola suggests that the ATCC 96836 strain might also produce a small amount of brassicicene E (Probable).
What are the official names of this protein?
16-O-methyltransferase bsc6, Brassicicene C biosynthetic gene cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: RS7_CLOBJ
Sequence: MPRKGHIAKRDVLPDPLYNSKVVTKLINSIMLDGKRGVAQKICYDAFEIIAEKSGKDAMEVFETAMNNIMPLLEVKARRIGGATYQVPIEVRPERRQTLGIRWMLIAARKRGERSMRERLAGELLDASNNTGAAVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: H32_CHICK
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2, Histone H3 class I.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HMBX1_HUMAN
Sequence: MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD
What is the function of this protein?
Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (PubMed:23813958, PubMed:23685356).  Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation (PubMed:23685356).  Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (By similarity).  Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) (PubMed:23813958).  Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination (PubMed:23813958).  Might also be involved in the DNA damage response at telomeres (PubMed:23813958).
What are the official names of this protein?
Homeobox-containing protein 1, Homeobox telomere-binding protein 1, Telomere-associated homeobox-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome, telomere. Nucleus, Cajal body. Nucleus, PML body. Note=Predominantly detected in cytoplasm (PubMed:16825764, PubMed:19728927). Localizes in a dynamic manner to actively processed telomeres (PubMed:23685356). Localizes to the periphery of Cajal bodies (PubMed:23685356). Associates with PML nuclear bodies in telomerase-negative cells (PubMed:23813958). SUBCELLULAR LOCATION: [Isoform 5]: Nucleus. Cytoplasm.
Protein: DCUP_MAGSA
Sequence: MSSSSKPFLRALAGETLTPPPFWLMRQAGRYLPEYRATRAEAGSFLDLCYNSDLACEVTLQPLRRYGFDAAILFSDILVVPDALRQHVAFKEGEGPVLTPIRSAEDLSGLDLSGLHDHLAPVYETVKKLSAAIPKTTALIGFAGAPWTVATYMIEGSGSKDFAKAKGMMFGQPELFARLMALLVQATGDYLIRQIDNGAEAIQIFDTWAGALPEDMFERWVIGTTRTLVERIRTERPGVPVIGFPRGAGYLYKRYVAETKVSGVSLDPSVPLHWAAAELQPKCTVQGNLDPLLLVAGGEALDAGIDRVLKALSKGPFIFNLGHGITPPTPPDNVARLAERVKGWKG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANPRC_HUMAN
Sequence: MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
What is the function of this protein?
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.  May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects.  May regulate diuresis, blood pressure and skeletal development.  Does not have guanylate cyclase activity.
What are the official names of this protein?
Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor type C, ANP-C, ANPR-C, NPR-C.
What is the protein family that this protein belongs to?
Belongs to the ANF receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: THIL_SYNY3
Sequence: MRDVFIVAAKRTPLGRFGGSLTNFSAADLGAHVMKSVLAQAGVGGDQLDLYIMGNVLRAGHGQLIPRQAALKAEIPDTVDGYAVDMVCSSAMMSVINAALTIRAGEGDLILAGGTESMSQTGFYLSHRARWGYKFLMGAPENLTDLLLHDGLTDSTNGEGMGEQTEKLAAEHGFSRIELDEVACLSQQRAAHATESGYFDSEIAPIEITSRKGTQVLASDEGIRSDTTVESLGKLRSAFAKDGVLTAGNCSQITDGAAALLLASGEAVEKYQLKPLAKILGGSWAAGTPSRFPELPITASQKLLAKLDKTLADFDLFENNEAFSVSNLLFERRLGVDRDKLNVNGGAIALGHPIGASGARIMVTLLYALQQRDKTLGLAALCHGTGGGTAIALERV
What is the function of this protein?
When expressed in E. coli with Synechocystis PhaB, PhaC and PhaE confers the ability to synthesize up to 12% (w/w) poly(3-hydroxybutyrate) (PHB) depending on the carbon source.
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Beta-ketothiolase PhaA.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.