PharMolix/UniProtQA huggingface dataset:
Protein: FECA_ECOLI
Sequence: MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLDKALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGFYTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYLNESTHEMRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQNNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQARYDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTFNLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF
What is the function of this protein?
FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.
What are the official names of this protein?
Fe(3+) dicitrate transport protein FecA, Iron(III) dicitrate transport protein FecA.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: IOLG_KLEP3
Sequence: MSLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHDVINASDVDAILVTSWDPTHEEYTLAAIAAGKPVFCEKPLAMSAEGCRRIVDAEMKAGRRLVQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSVGENYTTDMAITNTLIHELDVLRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCEVVGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPSAWDGYAASVAADACIKAQGTSEPVEVTLPECPAFYKR
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: BLH1_YEAS2
Sequence: MLPTSVSRSLYLKTFRSHLLRAPQIVLKRMSSSIDISKINSWNKEFQSDLTHQLATTVLKNYNADDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAATNQLRLNVLSELNLKEFELSQAYLFFYDKLEKANYFLDQIVSSADQDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPKDLYGDLPYSTTASRKWNSLLTTKLREFAETLRTALKERSADDSIIVTLREQMQREIFRLMSLFMDIPPVQPNEQFTWEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPRHPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKTTGVMDIELWNYPAIGYNLRQQKASRIRYHESLMTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDGLYVMTQKYFEEYCFQIVVDINELPKELASKFTSGKEEPIVLPIWDPMGALAK
What is the function of this protein?
The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells.  Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid.  Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin.  Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.  Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities (By similarity).
What are the official names of this protein?
Cysteine proteinase 1, mitochondrial, Bleomycin hydrolase, BLM hydrolase, Homocysteine-thiolactonase, HTLase, Hcy-thiolactonase, Leucine aminopeptidase 3, Y3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: ALDH_STAAW
Sequence: MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADNVYLEFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPKKIKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVIGKDKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSIAGYFK
What are the official names of this protein?
Putative aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NU3M_ONCGO
Sequence: MNLITTIITITITLSAVLATISFWLPQISPDAEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLNTPTLTLIWSTAVLALLTLGLIYEWTQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: THIC_ECOLI
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HSE1_MAGO7
Sequence: MFRAQATTPYDTAIAKATDENLTSEDWGAIMEVCDRVAGDDNGAKEAVQALIRRLAHRNANVQLYTLEVANALSQNCGKPMHRELASRAFTEALLKLANERNTHNQVKAKILEGTKEWSDMFKDDADLGIMYDAYYRLKQTNPQLQPPSAPQKNSLTDVDRQKEEEELQIALKLSLQEEERKKQQTPAGPSGAAGPSSSSAPDQAGTPSGQGADAGAGAAAVPLQPTGTGTTAATVSRVRALYDFVPSEDGELEFKKGDVIAVLESVYKDWWRGSLKGKTGIFPLNYVEKLADPTPDELQREAQMEAEVFSEIKNVEKLLTLLSTSSKDEDSEEIAKLYQQTSAIRPKLIKLIEKYSQKKDDFTQLNEKFIKARRDYEALLETSMSHPPQPSYHQYAVRPQGYGGSPTPYPTQGPPQQDPQRFYPPGPHPDQYPPSSPSPHLQRPGGTPGPGAQAPFYVAGAEVPSHGGPHPNQNFPPRDPGQRIPSAGKQPARLQTQQASSSPPPSAPYAAYSQPPAQQGSYGNPQELSTSAYDSPVASHPHPNPLGSNAPFAPATYPAEERYGTPSAAPAPLNPGGGQQQPYQYNSYQNQTPPQPANTQPPQGGMYSGQGYNDSSDAVGNVPPQPTSAAPPPPVPGSQRVHSPVYGGPPGAADSRFSLPSRMGPGAPSAPLGGPSSPGEQPQYKAYVPPGSSGPSAPSAPSVPADYYRQPGGTANY
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein HSE1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CASQ2_MOUSE
Sequence: MKRIYLLMVGVYLLSLSGAEEGLNFPTYDGKDRVVSLSEKNLKQMLKRYDLLCLYYHEPVSSDKVSQKQFQLKEIVLELVAQVLEHKNIGFVMVDSRKEAKLAKRLGFSEEGSLYVLKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIVNNKLEVQAFERIEDQTKLLGFFKNEDSEYYKAFQEAAEHFQPYIKFFATFDKAVAKKLSLKMNEVGFYEPFMDEPNVIPNKPYTEEELVEFVKEHQRPTLRRLRPEDMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFKPQIGVVNVTDADSIWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDNEDEDDDGDDNDDDDDDDDDNDNSDEDNEDSDDDDDDDE
What is the function of this protein?
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.  Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits.  Can bind around 60 Ca(2+) ions.  Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction.  Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
What are the official names of this protein?
Calsequestrin-2, Calsequestrin, cardiac muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the calsequestrin family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum lumen. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
Protein: 4HYPE_ROSAD
Sequence: MRVIDSHTAGEPTRLVVEGGPDLGPGSLIEKAACLEAEHMDFCASVVLEPRGHDAIIGALLLPPSQPDCAAAVIYFNNLQNLGMCGHATIGLAVTLAHMGRIDPGRHKFETPVGIVEVDLQDANTVSVVNVESYRLHKDVTVEVPGHGKVTGDVAWGGNWFFLVKESPFDLTLENVPALTAYTKTIRQALENAGVTGTDCAWIDHIELFGPPKDPFAQSRNFVLCPGGAYDRSPCGTGCSAKLACLAEDGVLAPGEDWIQESVIGSTYRISYQPGTTKGVIPTITGQAFVTSDAHLIFNPADPYRFGIRPQNWTTSWITRTLSVEHG
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: RBFA_CHLT2
Sequence: MAENRRMKKVNAMLREAIAKVILKDVKHPKISNRWITITRVSLSRDLQSACVYVSIMPHENSQEETLAALKASAGFIAFQASKDLVLKYFPDLNFYVEDIFSPQDHIESLLLKIAEQDKKTNP
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX4_MYCPA
Sequence: MHIEARLFEFIAGFFFLTALLYGVLTALFATGGEEWAGTTALALTGGLALIVATFFRFVARRIDTRPEDYEGAEISDGAGELGFFSPHSWWPILIALSGSVAAVGIALWLPWLIVAGVMFILSSVAGLVFEYYLGPEKH
What is the function of this protein?
Part of cytochrome c oxidase, its function is unknown.
What are the official names of this protein?
Probable cytochrome c oxidase polypeptide 4, Cytochrome aa3 subunit 4, Cytochrome c oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVC_DINSH
Sequence: MRVYYDRDCDVNLIKDKKVAILGYGSQGHAHALNLRDSGAKNLVVALREGSASAKKAEAEGLQVMGIAEAAAWCDLIMFTMPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPKAGVDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDTDATGRALEIGLSYCSAIGGGRSGIIETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQTGKFVRDFMQENTVGQPFFKGTRRLNDEHQIEAVGKELRGMMPWISAGKLVDQEKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RIR2_MESAU
Sequence: MFSVRVPLATITDQQQLQVSPLKALSLADKENTPPSLSATPVLASKVARRILQDVAEPESKVSTNPSVEDEPLLRENPRRFVVFPIEYHDIWKMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEQRVQEIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFKVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSFTLDADF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).  Inhibits Wnt signaling (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized to the cytoplasm in S phase cells. May localize to the nucleus in G2 phase cells.
Protein: Y2347_METMJ
Sequence: MSQDRLPQMVISIMLLANFDVSERCNIRPRSFDLIAKKGDNLVIIKVASHIDSVSADITWDLNLIARYLEATPLIVGERARDTDLERGVVYIRYGLFALNPETLYDYFVEGLSPMVYASPGGLYVRIKGDLLREVRERFRMSLGDLASHLGVSRRTISKYESGMGTTLDVAIKLEEIFNAPLVETIELLGYRTPEPEKHLESTPGDVLADLERMGMEIHAMRQAPFQALALFDRHTILTAYGTSQKIVKRASLIGNISQITKTFAMCVVTDYKKQKKIGKTLLIGEEHLHTLEDGSELIDMINE
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein Memar_2347.
Protein: M233_CONTS
Sequence: MMSKLGVLLTICLLLFPLTAVQLDGDQPADLPALRTQDISTDHSPWFDPVKRCCSRYCYICIPCCPN
What are the official names of this protein?
Conotoxin TsMMSK-011, Conotoxin TsMMSK-B012.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTB3_ANEAE
Sequence: MELTIEEMLIKQKETGAHYTPTDLGDIIAKRLINELKKSGISGTKKIRGLDPSCGDGELLLSLNRMGKFNNIDNIELIGIDEDKEAIKEADFRLNEMGINDAKLSGGDFLDMVDLEGNLSLFDDDLSKIEPVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITSNKYLANTTGESIRQFLAENYDIIEIMDLGDTKLFSGAVLQAIFFGTKKLNKGIRQTAPANFYKIYEETDPSKTEVSIKFETLFGLLESSNTGVFNVDEKFYSVSCGKLIVPDSFKEPWVMATDEEYNWITNINNNSYCTIQDLCDLKVGIKTTADKVFIKSTWEELPDEIKPEVEVLKLLISTDHASKWRPLERIGNQKILYTHENLNGKKKAIHFTQYPHALAYLETHRETLEGRKYVIKAKRNWYQIWLPQNPDHWALPKILFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNNDILFLILGISNTKYMTNYHDIAFNNKLYPGRTRYLTQYVSNYPLPNPEANYSQEIIDVLRELLFQNPNDERKIEIENQIENLTALAFGVERL
What is the function of this protein?
A gamma subtype methylase, recognizes the double-stranded sequence 5'-ATCGAT-3', methylates A-5 on both strands, and protects the DNA from cleavage by the BanIII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BanIII, M.BanIII, Adenine-specific methyltransferase BanIII, Modification methylase BanIII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: VG27_BPML5
Sequence: MITDTIVELEGVNGERFNLTTGDQGVYLATDVEGCFYDPPVKVVVEEPGNYPGARYLSHRALKRDIVFGVVILNDAKQGPRSWLSRDSEWRKAWAFNRTCKLYVTTPDSGTRYLKLALFESPTVKMDTDPRGKPLEVTVMSCIAYDPFWYEDDKVFSAKTKTDTRFDPSFWTPPWPWEELPKETLRIKVGREQGGLNPTDQYIFPKWTVPGSTEKVPNFPWPFPPNVPIPWETAPFTQFVIPDYSFEDEEFRNRRLKTPGLIYGENCVIDTDRREEQIASESGSPVWARMNGVRFRNSIPPYTEEAEFVIDASGCAPGQVVTLRLTRPWSRCWGLE
What are the official names of this protein?
Minor tail protein Gp27.
Protein: YQAG_BACSU
Sequence: MENNPYNMRNLPQIMRSARKAAGLSQYQIGKLIGGKDQRYVSDVENGLAKLTPELCIKWFEKCAAYEHIDLVHYLFKLHPTAAAPIDPALNECASNAVINMVHQLEEALQATKHLARWLTDNRPGKTEELPMADIKQIFDLIAANKTLIYSLVRTHGLKMQELADRWTRKALVDQVAMAKQEGRQAVSV
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YqaG.
Protein: RL31_MYXXD
Sequence: MKPEIHPVYPPSRVTCMCGNVVETKSTRGSFSVEICSNCHPFFTGKYKLVDTAGRIDRFRKKYGASPTSAKKA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: UBIG_SHIDS
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: ACCA_BURP6
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLTPWQVSQIARHPQRPYTLDYVSELFTDFHELHGDRAFADDQSIVGGLARFNGHACMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRVAEKFGLPIFTFVDTPGAYPGVGAEERGQSEAIGHNLYVMAELKTPIIATVIGEGGSGGALAIAVADTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIVNEPLGGAHRDPKGMAALLRRALGDSLRQFQGMSVDALRERRFERLMAYGKFKETTPRA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_YERPA
Sequence: MILIEHILGNVKKDPVWREKLKDATFDLLILDQREAQKSRCRKSSTQGLDLGISLDRNVVLADGDVLAWDEETNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKHNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLTNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHIHGIHSHEEGHSHGDHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_ECO57
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_YERPA
Sequence: MALNLQGKQAIVAEVKEVAKGALSAVVADSRGVTVDKMTELRRAGREAGVHMQVVRNTLLRRIVEGTPFECLKDTFVGPTLIAFSAEHPGAAARLFKAFAKDNAKFEVKAAAFEGELIPAAQIDRLATLPTYEEAIARLMGTMKEAAAGKLVRTLAALRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TBX37_CAEEL
Sequence: MYSCTSPSGIEVSLNKPEIWEKFYPKTEMIVTRKRGRVIFPHLDYNVKGLDPDSLYSIYIHLERVDGIKYKFDAGEWKEAGKGDPILPIQYKEHPRGKRTGTEWMSEPVSFAHLKITNDPENKDQKLILAQSLHKYIPVLHIKQLDPYKGTFQMDFHGVEFRLEATQFIVVTAYQNEELTKLKVHHNKFASGFRSNGKRRLSSESENSENSPPKRSASAISSLTPPAISPPMDYTQQNPYFFNQNFFSTPQSHQPQFAAHSANAQNYNNFGAQNGAQFDWNVYYQRQWYWQQQMMMSGGIGQPQMLNNGFPNL
What is the function of this protein?
Transcription factor (By similarity).  Required for mesodermal induction, acting redundantly with transcription factor tbx-38 (PubMed:15056620).  Together with tbx-38, acts by inducing cell fates in the AB lineage, thereby playing a role in development of the anterior pharynx (PubMed:15056620).
What are the official names of this protein?
T-box protein 37.
What are the subcellular locations of this protein?
Nucleus.
Protein: VOA1_YEAST
Sequence: MVFGQLYALFIFTLSCCISKTVQADSSKESSSFISFDKESNWDTISTISSTADVISSVDSAIAVFEFDNFSLLDNLMIDEEYPFFNRFFANDVSLTVHDDSPLNISQSLSPIMEQFTVDELPESASDLLYEYSLDDKSIVLFKFTSDAYDLKKLDEFIDSCLSFLEDKSGDNLTVVINSLGWAFEDEDGDDEYATEETLSHHDNNKGKEGDDDILSSIWTEGLLMCLIVSALLLFILIVALSWISNLDITYGALEKSTNPIKKNN
What is the function of this protein?
Accessory component of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:29526695).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:29526695).  Functions with VMA21 in assembly of the V0 complex (PubMed:18799613).
What are the official names of this protein?
V0 assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the VOA1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein.
Protein: MURG_LEUCK
Sequence: MRVILSGGGTGGHIYPALALAEVIKQHEPDAEFLYVGSERGVEANIVPKTGMAFKQLAVQGFSRSLSLHNIKTVQLFLKAVKVSKKIIKEFKPDVVIGTGGYVAGAVVYAAQRMNIPTVIHEQNSVAGVTNKFLARGATKIGVAFEVAKQQFPSEKVVLVGNPRAQQVAQLKSTFSWQTIGLRDDKATVLIFGGSQGAPAINLAVIDAIPEFNERSYQVVIVTGPKRYDNVLDLLRERNIEAADNIRILPYIDNMPNVLKQTDAIVSRAGATSIAEITALGIPSILIPSLHVTGDHQTKNAQSLVDVGAAINITESDLNGQSLIAAVDTLLLDENVSDKMAAQATKVGMPDAGERLYQLILQAMANKKD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.