PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_CHLCV
Sequence: MLQTYLQSIMNQSHLTYDEVESVTNLMLNGADPHQIAAFLAVLKYRGETPTEVAGMISALQKQATPVNLPFPALDIVGTGGDLANTVNISTGSAILAAACGIPIAKHGNRSVSSQSGSADVLEALGIEIEMSPEELLSCVQEVGIGFMFAPIYHPSLKKLAPIRKGMKFPSVFNILGPLLNPANTEYALIGVSNEPILELMSEVCLKFKNTKRTFLFHGSGLDELTTLGKVVGYDIQQGKKTRLEIDPTSLGFNSCKIEDLKGGNSKLNACILKKAFMGQQSAIADALIFNAGAAMWVFGNAATLEEGIHSARKTLMEGEALRVLAQWAAFSQQLKLKRGSCN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: Y462_BACHK
Sequence: MGEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFKELELPNLKRKEMDENRIEHVEFNDIRKTGLWGNIDKKRTMISAYKRNAMRGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVPEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFREESGEKMA
What are the official names of this protein?
UPF0229 protein BT9727_0462.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: GRPE_PROMA
Sequence: MKEEVSTSNQEDLVADQEVIASEESDLSPKEEKVSESTIDDDDSLNDAELQSNKQTLDNEARLEQLEKEHETLRSQYVRIAADFDNFRKRQSRDQDDLKLQLTCNTLSEILPVVDNFERARQQINPEGEEALTIHRNYQNLYKQLVDVLKKLGVAPMRVVGQSFDPTLHEALLREPSELMVEDMILEELVRGYHLNGRVLRHAQVKVSMGPGPKVDEEDKQIDEDSQADKRDEATTASNELD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRL_SALDC
Sequence: MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNVKPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTAVPINETEVVERLEYTLREFHEKLRDLLISMELALEPSDDFNDEPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_HAES1
Sequence: MYNLQEITEKARKAIDALQDNSIESLEAIRVEYFGKKGHFTQLMQGLRDVSAEERPAVGAKINEAKQKVQAILNAKKVEWEEIALNERLAQERIDVSLPGRKMELGGLHPVSITINRVVQFFSKLGFTVEIGPEIETDYYNFDALNIPKHHPARADHDTFWFDAERLLRTQTSGVQIRTMEKMCPPIRIMAPGKVYRNDYDQTHTPMFHQIELLYVDKKANFTELKGLLHDFLRAFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPNEYSGFAVGMGVERLTMLRYNVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX4_LEIHE
Sequence: GVRDAYIADDKNCVYTCGANSYCNTECTKNGAESGYCQWFGKYGNACWCIKLPDKVPIRIPGKCR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (By similarity).  Intracerebroventricular injection into mice induces immediate convulsions and urination followed by death.  Is toxic to insects and mice.
What are the official names of this protein?
Toxin Lqh4, Lqh IV, LqhIV, Toxin IV.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ERFC3_SOLLC
Sequence: MDYSSRDDLLFHYNSLPFNVNDTQDMLLYNLVAEGSSQETVNSSSSYGIKEEEVTSYEEERKDKNYRGVRKRPWGKYAAEIRDSTRNGVRVWLGTFDNAEEAALAYDQAAFAMRGSMAILNFPVEIVKESLNEMKCRFDGNCSPVIELKKRYSMRRKSVSRKNRARKDVVVFEDLGAEYLEELLISSESITNW
What is the function of this protein?
Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995).  Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419).  With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419).
What are the official names of this protein?
Ethylene-response factor C3, Sl.ERF.C.3, Ethylene-responsive element-binding factor C3, Ethylene-responsive transcription factor C3.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTNC_ENT38
Sequence: MIRAIVTDIEGTTSDIRFVHNVLFPYARERLAAFVTAQQYAEPVKSILDNLRDEIAAPHATIGELVDALFTFMDEDRKSTALKALQGIIWQDGYVNGDFTGQLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFGYSDEGDITHLFSGYFDTRVGAKRDVQSYQNIAAQIGVSPSQILFLSDIHEELDAAEQAGFRTLQLIRGDDDGASHHHQVHQFDEINPEQIPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: CCD1_ARATH
Sequence: MAEKLSDGSSIISVHPRPSKGFSSKLLDLLERLVVKLMHDASLPLHYLSGNFAPIRDETPPVKDLPVHGFLPECLNGEFVRVGPNPKFDAVAGYHWFDGDGMIHGVRIKDGKATYVSRYVKTSRLKQEEFFGAAKFMKIGDLKGFFGLLMVNVQQLRTKLKILDNTYGNGTANTALVYHHGKLLALQEADKPYVIKVLEDGDLQTLGIIDYDKRLTHSFTAHPKVDPVTGEMFTFGYSHTPPYLTYRVISKDGIMHDPVPITISEPIMMHDFAITETYAIFMDLPMHFRPKEMVKEKKMIYSFDPTKKARFGVLPRYAKDELMIRWFELPNCFIFHNANAWEEEDEVVLITCRLENPDLDMVSGKVKEKLENFGNELYEMRFNMKTGSASQKKLSASAVDFPRINECYTGKKQRYVYGTILDSIAKVTGIIKFDLHAEAETGKRMLEVGGNIKGIYDLGEGRYGSEAIYVPRETAEEDDGYLIFFVHDENTGKSCVTVIDAKTMSAEPVAVVELPHRVPYGFHALFVTEEQLQEQTLI
What is the function of this protein?
Cleaves a variety of carotenoids symmetrically at both the 9-10 and 9'-10' double bonds.  Active on beta,beta-carotene, lutein, zeaxanthin, all-trans-violaxanthin, 9-cis-violaxanthin and 9'-cis-neoxanthin.  With most substrates, the carotenoid is symmetrically cleaved.  Probably not involved in abscisic acid biosynthesis.
What are the official names of this protein?
Carotenoid 9,10(9',10')-cleavage dioxygenase 1, AtCCD1, Neoxanthin cleavage enzyme NC1, AtNCED1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=On the exterior surface of the plastids.
Protein: Y2330_MYCLB
Sequence: MQPGGDMSALLAQAQQMQQKLLETQQQLANAQVHGQGGGGLVEVVVKGSGEVVSVAIDPKVVDPGDIETLQDLIVGAMADASKQVTKLAQERLGALTSAMRPTAPPPTPPTYMAGT
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein MLBr02330.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TRUA_HALS3
Sequence: MPRRAFRVAYDGRPYHGFQRQPDVSTVAGELFGALRRLDVFDGAKPPGYAAAGRTDAGVSARAQTVAFDAPAWLTPDAFTGALPDPIQVWAHADAPPEFHATHDAVARTYVYYWYAPDSRATDDRAAGALDRLTGTHDFHNLTPNTTNTVRELDATLDRDGAFRVITVRAGGFCRELVRRVVSLVQLVTETGDTDRIDTVLGDEPVAGPDGVPPADPHPLVLHAVAYDGLSFTVDEDAAERARTTFRAARADHHERARVAGHLASI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: KDSA_HELPY
Sequence: MKTSKTKTPKSVLIAGPCVIESLENLRSIATKLQPLANNERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQTIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKTRDKSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLKIMREFAPVIFDATHSVQMPGGANGKSSGDSSFAPILARAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELEQLVTDMLKIQNLF
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MARN8
Sequence: MSDYNIFTSESVSEGHPDKLADQISDAVLDAILTDDPHARVACETMVKTGVAIVGGEITTSAWVDLEDLVRGVIKDIDYTSSEVGYDGDTCGVINIIGKQSVDIAQGVDRQKPEDQGAGDQGLMFGYASNETDVLMPAPITFSHRLVQRQAEARKSGLLPWLRPDAKSQVTCRYENGKVVGIDAVVLSTQHDPDVTQADLKEAVMELIVKHTLPAELLHKDTQFHINPTGKFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAEKCEIQVSYAIGVAQPTSISLNTFGTGKISDDKIIDLVRAHFDLRPYAITNMLDLLHPMYRATAAYGHFGRDPYEMTVGGKTFTAFPWEKTDRAAALKDAAGI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_PSEMY
Sequence: MQKIRRDDEIIVIAGKDKGKRGKVLKVLADDRLVVGGINLVKRHTKPNPMSGVQGGIVEKEAPLHASNVAIFNSETNKADRVGFKIEDGKKIRVFKSTQKPVGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PYM1_ARATH
Sequence: MGSRSGEQGKRMAELSKNLKEGERILEPTRRPDGTLRKPIRIRPGYTPEDEVVKYQSKGSLMKKEMASQGPPGYEPDPAPKPKTKAAKRNERKKEKRLQATAEKANSSEDGSASNGSQSVNVLASEMEALDVSSNNDVCGGAPNPGTTGEDVEKRIRALKKKIRLTEAQQQKTASRDLNPEQLEKFSKLEEWRQELKALEDKAA
What is the function of this protein?
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.  Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs (By similarity).  Can increase in vitro the expression from reporter constructs that contain leader introns required for the expression of different genes.  In association with MAGO and PYM, participates in intron-mediated enhancement of gene expression (PubMed:21676911).
What are the official names of this protein?
Partner of Y14 and mago, AtPYM.
What is the protein family that this protein belongs to?
Belongs to the pym family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Can shuttle between the nucleus and the cytoplasm, but is mainly cytoplasmic.
Protein: C3H49_ORYSJ
Sequence: MAHRLLRDAQADGWERSDFPIICESCLGDNPYVRMLRAEYDKECKICARPFTVFRWRPGRDARYKKTEICQTCCKLKNVCQVCLLDLEYGLPVQVRDTALSTNSNDAIPRSDVNREYFAEEHDRRARAGIDYDSSNGKARANDTILKLQRTAPYYKRNRAHVCSFYVRGECTRGAECPYRHEMPETGELSQQNIKDRYYGVNDPVALKLLSKAGEMPSLTPPDDESIRTLYIGGLDSRVTEQDLRDQFYAHGEIETIRMVLQRACAFVTYTTREGAEKAAEELANKLVIKGVRLKLMWGKPQAPKPEEDEAGRQGHVAHGGMLPRAVISQQQSGDQPQPPGMEGQQQPASASYYFNIPAPPAAERTLYPSMDPQRMGALVESQEGDGKPGPQQAGQGQASSSSGQSYPEPPPPYYHGGQYPPYYPPYGGYMPPPRMPYQQPPQYPAYQPMLAPPAQSQASSLQQPAPATQQLGQGPQQQTTQNGMT
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 49, OsC3H49.
Protein: LEUC_BUCRP
Sequence: MKKTLYEKIYDAHIVHEEKNNASILYIDLHLLHEVTSPQAFDSLRIKNRVVRQPKKTFATMDHNVSTESKDINASGSMAKIQMQQLIRNCNQFNISLYDLNNPKQGIVHVIGPEQGMTLPGMTIVCGDSHTSTHGAFGALSFGIGTSEVEHVLVTQTLKQQRLKNMKIQIKGKIKNFVTAKDIILFIIGKLGTSGGSGYVIEFCGDVIKKMNMEERMTVCNMAIEMGAKSALIAPDETTFLYLKGRRYSPQGKFWEEAVKYWKTLITRSKAFFDKEFTFDVSNLSPQITWGTSPDQVLSINEKIPDFNFFKDSVKKNLARSACDYMNLKPGSYLTDIKIDKVFIGSCTNSRIEDLRSAAKILKNKKISKNIKAILLPGSGTGTVKKPAEKEGLDKIFIDAGFEWRLPGCSMCLGMNNDKLSDGERCASTSNRNFEGRQGRGGRTHLVSPIMAAAAIYGRFIDVRNLDSETN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SULF1_CAEEL
Sequence: MISNLRISNYFIIFYVLFLIIPIKVTSIHFVDSQHNVILILTDDQDIELGSMDFMPKTSQIMKERGTEFTSGYVTTPICCPSRSTILTGLYVHNHHVHTNNQNCTGVEWRKVHEKKSIGVYLQEAGYRTAYLGKYLNEYDGSYIPPGWDEWHAIVKNSKFYNYTMNSNGEREKFGSEYEKDYFTDLVTNRSLKFIDKHIKIRAWQPFALIISYPAPHGPEDPAPQFAHMFENEISHRTGSWNFAPNPDKQWLLQRTGKMNDVHISFTDLLHRRRLQTLQSVDEGIERLFNLLRELNQLWNTYAIYTSDHGYHLGQFGLLKGKNMPYEFDIRVPFFMRGPGIPRNVTFNEIVTNVDIAPTMLHIAGVPKPARMNGRSLLELVALKKKKKKHMTALKPWRDTILIERGKMPKLKKIRDRYIKQKKKFNKENRLSKECKRRKWQRDCVHGQLWKCYYTVEDRWRIYKCRDNWSDQCSCRKKREISNYDDDDIDEFLTYADRENFSEGHEWYQGEFEDSGEVGEELDGHRSKRGILSKCSCSRNVSHPIKLLEQKMSKKHYLKYKKKPQNGSLKPKDCSLPQMNCFTHTASHWKTPPLWPEELGEFCFCQNCNNNTYWCLRTKNETHNFLYCEFVTEFISFYDFNTDPDQLINAVYSLDIGVLEQLSEQLRNLRKCKNRQCEIWSTSQMLRSPKLVDLRVNEKSFLTYQPEKT
What are the official names of this protein?
Putative extracellular sulfatase Sulf-1 homolog, CeSulf-1.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus, Golgi stack. Cell surface. Note=Also localized on the cell surface.
Protein: Y1382_ENT38
Sequence: MQFSTTPTLEGQPIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFKELGEQAKALGADAVVGIDIDYETVGKDASMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein Ent638_1382.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RECF_STAS1
Sequence: MKLKTLQLQNYRNYESISLNCHPDVNILIGENAQGKTNLLESIYTLALAKSHRTSNDKELIRFDSDYAKIEGDLSYRYGEMPLTMYITKKGKQVKINHLEQSRLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLSQYQRILKQKNNYLKQLQYGQKTDSTMLEVLNQQFAEYALKITLRREHFINELESLAKPIHSGITNERETLSLNYLPSIKLENKDKSETERLEEVLTILNDNMEREKDRGVCLYGPHRDDLGFNVNGMDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQSHLLSTIQHKVQTFVTTTSVDGIEHEIMKNAKLYRINQGEIIK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_RHIE6
Sequence: MTHPPKTPLLDQVIYPADLRKLEDRDLPQLAREVRDEMIDAVSRTGGHLGAGLGVVELTIAIHSVFDTPDDRLIFDVGHQCYPHKILTGRRDRIRTLRQENGLSGFTRRAESEYDPFGAAHSSTSISAGLGMAIAADLDKNDRRVIAVIGDGAMSAGMAYEALNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLASGRTYMGFRDFGKKLTAYLGKNIDRAITRAVEHARGYVTGGTMFEEMGFYHIGPIDGHSFDHLLPVLRNVRDNARGPVLIHVVTQKGKGYPPAEAAADKYHGVNKFDVITGAQARVKPNAPSYTSVFAEALVQEAALDDKIVGITAAMPNGTGLDKLAEAFPSRCFDVGIAEQHAVTFAAGLAAEGYKPFAALYSTFLQRAYDQVVHDVAIQGLPVRFPIDRAGFVGADGPTHAGSFDTAFLATLPGFVVMAAADEAELKHMVRTAVAYDAGPISFRYPRGEGVGVDMPARGEILQIGKGRIVKEGTKVALLSFGTRLADCLLAAEDLEAAGLSTTVADARFAKPLDHDLIRQLARHHEMLITVEEGSVGGFGSQVMQYLSSEGLLDNGLKIRSLVMPDIWMEQAKPEAMNAHAGLDRAGIVSTVFRALGRGVAVGVAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: QUEA_BURCH
Sequence: MFTLSDFDFNLPPELIAQTALPDRTASRLLEVDGSVAPARLVDRHFAELPSCIAPGDLLVFNDTKVLKARFFGQKASGGKIEVLIERVTGTHTALAQIRASKSPGAGTTLRLADAFDVTVGERVEPFFTLHFPAPCLDLIEQHGRLPLPPYIEHDADATDETRYQTVYASNPGAVAAPTAGLHFDQPLLDKLDAMGVERATLTLHVGAGTFQPVRVENIAEHKMHSEWYDLPQSLVDKIAATRARGGNVIAVGTTSMRALEAAARSADEAGRPLAATQAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGVETIRAAYRHAIEERYRFFSYGDAMLLTRRDTPEAPGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADSSP_HUMAN
Sequence: MAAANKGNKPRVRSIRFAAGHDAEGSHSHVHFDEKLHDSVVMVTQESDSSFLVKVGFLKILHRYEITFTLPPVHRLSKDVREAPVPSLHLKLLSVVPVPEGYSVKCEYSAHKEGVLKEEILLACEGGTGTCVRVTVQARVMDRHHGTPMLLDGVKCVGAELEYDSEHSDWHGFD
What is the function of this protein?
Adipocyte-secreted protein (adipokine) that acts as a key regulator for white adipose tissue (WAT) thermogenesis and glucose homeostasis at least in part through activation of protein kinase A (PKA).
What are the official names of this protein?
Adipose-secreted signaling protein.
What is the protein family that this protein belongs to?
Belongs to the ADISSP family.
Protein: RNPH_ACIBS
Sequence: MRIDQRALDQLREVKITRNYTRYAEGSVLVEFGHTKVLCTASIDNSVPRFLKGQGQGWVTAEYGMLPRSTHSRCDREAARGKQTGRTQEIQRLIGRSLRAMVDLKKLGENTITIDCDVIQADGGTRTASITGAAVALVDAMNVLLAQKKIKQDPLKGLVAAISVGMYQDEVLLDLCYEEDSNCQTDLNVVMTQAGEFIEIQGTAEDKPFTRAQSNAMLEMAEKGIAELIKKQQEALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: FBX28_HUMAN
Sequence: MAAAAEERMAEEGGGGQGDGGSSLASGSTQRQPPPPAPQHPQPGSQALPAPALAPDQLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGNSSGSGQNEESPRKRKKATEAIDSLRKSKRLRNRK
What is the function of this protein?
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
What are the official names of this protein?
F-box only protein 28.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: Y191_CLOAB
Sequence: MYGSLIRIKEIINDLNPSERKIAEYILNNSKAISDLSIKELAGKSGSSKSAVVRLCKILNYKGYKEFRIAIAKDTVNVDKEENRYTDINPKDDLHTIIKNISYNNKKSIDNTMEVLSEELVEKASEAISKAYRVDFYGIGASYIVAMDAFQKFMRINKNVRATPDTHLQVEFASNLKKGDVAVAISYTGETKDTFESIKAAKEAGATTISVTKFGSNSISDLCDINLFVLSPEITFRSGAMSSRIAQLNVIDILFTSVAGRMFEEVKEFLENTRKSTRVKRIK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator CA_C0191.
Protein: MTNA_CRYNB
Sequence: MVAAAPSNKEPLPDMMTSIRLDQSGRVEIIDQLLLPHSVVWMPVSTPEEAFDAIKTMRIRGAPAIASLAALTLRSYLSSSSSPVSSSSSSSDVISWVGQTIDYLQSSRPTAVNLGEAMDRIRAALKDSEAQNQTAGDIIQRVKKICGDVHDEDLERNMKMGRLGAEWLWKKRGGGKKGLKVMTVCNTGSLATSGYGTAIGVITALFQEDHLDTAYYAQTTPYHQGSRLTSLELTTLQIPACMICDTMLGSLFQHEDIDGVIVGADRVVKNGDTANKIGTYQAAVLAQRHNVPFMVVAPVTTIDLSLPTGAEIHIEHRPAAEATQVRGLDTETGKLSVVRITPEGVGEGDKPWQRVYNPSFDVTPAELISAVVTEKGVAERKEGEKSIDVASIC
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRUB_CLOPS
Sequence: MNGVINIYKNTGMTSFDVVAMVRRVAKMKKVGHTGTLDPEASGVLPVCLGKATKIIDYIMENKKVYRVNLKLGMVTDTYDLEGEVLREEDASHITKDEILNCINSFVGTIDQVPPMYSALKQNGVRLYELARQGIEVHREARKITIYSIENIKIESNDNIQMDVCCSKGTYIRSLCYDIGEKLNVGATMTALERIQNGPFIKEEAINIEDLTEELLEKHIISIEKALDSFEKITVNEKFGKLLRNGVKVFDNRMYSEEVEFNKLYRVYEDNGVFLGLGKRDEKGFKLEKLLIEE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: KAD_RHOE4
Sequence: MRLVLLGPPGAGKGTQAAILSEKFGVPHISTGDLFRANIGQATALGVEAKKYIDAGELVPSSITNDMVKARVAEPDAANGFLLDGFPRSVEQAQALEGILKDLDTRLDGVLSFVVDEDIVVERMLARGRADDTEDVIRNRLRVYRDETSPLFDYYKDSIVSVDAIGEVEEVNARALAALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PD1_MYCBO
Sequence: MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLYAGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSPWLPRGTDA
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase 1, G6PD 1.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.