PharMolix/UniProtQA huggingface dataset:
Protein: F16PA_SHESM
Sequence: MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKVDGTVRGLASEEEDHVVEVSANGKYLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTETSFLQSGRNQLAAGYVLYGPSTMLALTTGQGVQLFTLHPETNEFLLTNAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHRVLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQRVAVILGSANEVDACLSYHGIDYSEEPTLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SYNR3
Sequence: MSDALPLLLRAARGEQVERPPVWMMRQAGRYMKIYRDLRDKYPSFRERSENPDLSYEISMQPYNAFQPDGVILFSDILTPLPGMGIDFDIIESKGPQINDPIRNLAQVEALRPLVPAETMPFVGEVLGRLRSSVGNNATVLGFVGAPWTLAAYVVEGKSSKNYAVIKAMAFREPEMLHKLLNHFAESIATYLRYQIDSGAQVVQMFDSWAGELSPADYDTFAAPYQRKVVELVKQTHPDTPMILYISGSAGVLERMGRTGVDFISLDWTVDMADGCARLPHHLGVQGNVDPGLLFGTPEAIRVRIDDTVRKARGRRHILNLGHGILPGTPEENGAAFFEAGKTVMDRIGARV
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_LIMRJ
Sequence: MAKEKQEEQQKQTAPENEKAPKKDIKKEASDKKGDQTSKLKEEIADLKKQLADKDDKYLRAEAEIQNMTNRFNKERAQILKYDGQDLAKSILPVLDNLKRALAIEVVDDNGKQLKKGIQMVHDHLVKALNDHGITEIKADGETFDPTLHQAVQTVPVEEGQKPETVVNVLQAGYQLKDRVLRPAMVVVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_STAAE
Sequence: MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MINY4_BOVIN
Sequence: MDTLFVEEVAASLIREFLSRKGLKKTYVTMDQERPRSDLSINSRNDLRKVLHLEFLYKENKAKENPLKTNLELITRYFLDHFGNIGNNVTQETRIPELSVPKKSNKLPLRSSETTLVNIYHLADEDETWRTSLSEISKARHDSLDGDVLGHFVSSKRSSHKSRPIKTVAGESPTVASAWEKTDKLPMSEPSLDTKRMGEKVRPKSGLIVRGMMAGPIASSPQDSLRKRSLRRSPALSSATQPHKEGSPQEPELSTHTSTCPTPLEGPASSTASTSRSPQGPLSELTWEKQRTSPGSPPHLPGKGLLPRGSGRWRDLSEDSPAVDSGSEAIRTPPKFSLSSGNVPKTQERPERAFERQGSQPASLRKNQLSVSNKLEGDLDVLQLEDVEDELVREEIILSPVSSVLKLQVVSKPIDLSVAKDIKTILFGSSFCCFSDEWKLQSFSFNDSVSLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDSSADCARLQPSNARRTHCLALAIADIVWRAGGCERAVVTLASGTQHFSPTGKYKADGVLETLILHSLTCYEELVTFLQQSIHQFEAGPYGCVLLTLSAILSRSTELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGKAVSNVFNDVVELDSGNGDVTLLKGISTRSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSVLFSQQLELLRDWRAERLFDLYYYDGLANQQEQIRLTVDTTQTVPEDRDNGLVPPLELCNRTKWKGASVNWNGSEPIL
What is the function of this protein?
Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4, Probable deubiquitinating enzyme MINDY-4.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
Protein: SRBS1_HUMAN
Sequence: MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMDLTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDHLALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGVHTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGPGGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
What is the function of this protein?
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor.  Required for insulin-stimulated glucose transport.  Involved in formation of actin stress fibers and focal adhesions (By similarity).
What are the official names of this protein?
Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Nucleus matrix. Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
Protein: POT11_ARATH
Sequence: MAARVEAATMGGEIDEEESDERGSMWDLDQKLDQSMDEEAGRLRNMYREKKFSALLLLQLSFQSLGVVYGDLGTSPLYVFYNTFPHGIKDPEDIIGALSLIIYSLTLIPLLKYVFVVCKANDNGQGGTFALYSLLCRHAKVKTIQNQHRTDEELTTYSRTTFHEHSFAAKTKRWLEKRTSRKTALLILVLVGTCMVIGDGILTPAISVLSAAGGLRVNLPHISNGVVVFVAVVILVSLFSVQHYGTDRVGWLFAPIVFLWFLSIASIGMYNIWKHDTSVLKAFSPVYIYRYFKRGGRDRWTSLGGIMLSITGIEALFADLSHFPVSAVQIAFTVIVFPCLLLAYSGQAAYIRRYPDHVADAFYRSIPGSVYWPMFIIATAAAIVASQATISATFSLVKQALAHGCFPRVKVVHTSRKFLGQIYVPDINWILMILCIAVTAGFKNQSQIGNAYGTAVVIVMLVTTLLMTLIMILVWRCHWVLVLIFTVLSLVVECTYFSAMLFKIDQGGWVPLVIAAAFLLIMWVWHYGTLKRYEFEMHCRVSMAWILGLGPSLGLVRVPGVGLVYTELASGVPHIFSHFITNLPAIHSVVVFVCVKNLPVYTVPEEERFLVKRIGPKNFHMFRCVARYGYRDLHKKDDDFEKRLFESLFLYVRLESMMEGGCSDSDDYSICGSQQQLKDTLGNGNENENLATFDTFDSIESITPVKRVSNTVTASSQMSGVDELEFINGCRDAGVVHIMGNTVVRARREARFYKKIAIDYVYAFLRKICREHSVIYNVPQESLLNVGQIFYV
What is the function of this protein?
Probable potassium transporter.
What are the official names of this protein?
Potassium transporter 11, AtPOT11.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MLTC_ECO81
Sequence: MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGMRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: USPB_SHIDS
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 6PGL_SALCH
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGVLTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEVQPRGFNIDNSGKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: PIGB_DANRE
Sequence: MEKIRERFKQSKSSNESVRLRKRSSILYSTDDRKLQTLKIFGINITVFIVLVRLLNCVLVQTSFVPDEFWQSLEISHRMVFGYGYETWEWKEGIRGYSYPLLFALMYKLLQLISYDTVYLLVFVPRVFQALLAAYADVKLYKLILQWETPDVAKWTCFCQLCSWFAWFCCSRTLTNTTETALTTLALCFYPLPGSKTHSSWKYLTLVSLAVVIRPTALIVWFPLIFYHFCTDQDKLKLITHRYFPIGVLALGVSTLIDSFFYGKWIFVQWNFLKFNVLHNVGEFYGSHPWHWYWTQGLPVVIGPHLPLVLHGCLLSTRKHTILLLTIIWTTAVYSLLAHKEFRFIYPVLPFCMIFCGLSLAKLQAWRKAAAGALLLFNLCPALYTGLVHQRGALDVMHVLQPLCVSSQSPNPPELLFLMPCHSTPLYSHLHCPLKLRFLECPPDLTGRQDYMDEADVFFSDPLHWLNTSFPLRSTLPSHLVLFDSLQKEISSFLEENSFAKQAEIFHTHFPEGRVGKNILIYSRRSEMKINEGFIL
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Phosphatidylinositol-glycan biosynthesis class B protein, PIG-B.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UNC13_CAEEL
Sequence: MDDVGDYNDDQLSDGMSMRLLCITIKKARLQGAVDEFNSYVTVKLQTVKSTTVAVRGNLPCWEQEFIFETNRPDDGMVLELWAKGVLWDKLIGVHYMPLSEIRYSNAAGSGQWLQMDHELETRNGQTVGTRGPTGHNLLTDVRFELPFDVQGHDEDIQSRLLALNGLIEHDQLGPNNHHRAPFNHSGLSEDSDYTSDVSVPVNHHQLHPNSSAHQYESHLHPHRTRQLLHTREGAASYEDEEDAYHARHQPESDDYNHQDTYDQHSSYYNDEYAPSGSSSQYQRQGYQDQDQQHQNIYEDTVTPVREFGESAVPPAASSSRRQFDQVYGYASSSEERYDTPMSSGRLPRDEPILEHSEPEYVYDQNGYPEEDNYGINPTYSEDHFEGQTNDYSTTHQEPNDFRNDYNSSYQREYWNESEPLSYNSRPPNGHIRTGANTWREPSTSSRPTSSQAWNYQDDTHQYDEVDRGSRVSFTRTPSVDRTDRPSESGGGFYDEMSESGRPGRPDSHHNWRYDSIQEEDNEKDNWKQHVEGYEEGQEEKQKDNQKPNDHSAASPQDHYHRSDSTAQQDFGNNIVRQTIQEEEEKRNYQELWHNAYKRVCADLGIKSSQASLVATTGGTLLQNLFLYRPKLAPAGHGATASQFQSPAGATRFYANHNNNNNNVSKNELDSTTETPPDPSRTPSTSSMNPVPSLAVPMSPGPYLNSDPPSPVSPNPQIKRSIYRIKESYEDRNGGRERIYTTNLVSVYLEKMKPPDELEEGSSGSMRETQNEIKNGTQLHNAESNIFFPQDSVPKSISYNAGNLKNTSITTSKTSSAITNHSSLPPQPPSKPASRDSDPMKQLLTFSKSFKKVRRVRSAMPRRRKRKRVKIKKSRSCPILWKTEKTPHPMKSKSMTCIRIPKKTVIAPLRKEIKIVRMKPPAARCESDSKAHKKKNLLDVYKDMGKSTVLDGNGSSAANAFYKSIDAAPNMNVARTKTSIPLVSELVLKTMATKRAQAGLANAARTTFSDTELKTHVYKKTLQALIYPISATTPHNFATTTFQTPTFCYECEGLLWGLARQGLRCTQCQVKVHDKCRELLSADCLQRAAEKSTKHGEADRTQSLVNVIRDRMKIQEQNKPEVFQMIRTVFDVDENIQKETLKTVKASILEGSSKWSAKITLTVLCAQGLIAKDKTGKSDPYVTAQVGKTKRRTRTIHQELNPVWNEKFHFECHNSTDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTVIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLHINVEIKGEEKLAPYHVQYTCLHEHLFAAHCVDEEVKLPKVRGEDSWKVCFQETGQEIAEEFAMRYGIESIYQAMTHFACLCTRYMCAGVPAVLSTLLANINAYYAHTTATSAVSAPDRFAASNFGKERFVKLLDQLHNSLRIDLSAYRNHFPSSSPAKLQDLKSTVDLLTSITFFRMKVLELASPPRASTVVRECAKACMQQTYQLMFESCAEQFPILDTSVQFWYEFIDYIMRVIEEDQKNYTPALNQFPQELNVGNLSAETLWSMYKNDLKMALEEHAQKKRCKTPEYMNLYFKVKGFYFKYVADLSTYKSSIPEFPAWFIPFVMDWLNENDEHSMDILRNAYNVDKADNFPQTSEHTKFSNSVVDVFTQLNAALKLLKQMDCPNPEVAADMMKRFSKTLNKVLLAYADMVQKDFPKFAHDEKLACILMNNVQQLRVQLEKIYETMGGAELDEHIGQVLTVLQKKLNSVLDRLSAEFVTTLEPHIHEQTIKLGMLLVKIKGPQLQKTQVQPEADAVLEPLMDLLEGSLRRYADQCEKTVLKYILKELWKITIVNMEKRVVLPPLSDKALLKQLPNAKIGDVTKLMSTNIQSIKGMNSVKDMMDMARESEKSLTPRQCTVLDCALDAIKDSFHASGKGLKKSFFEKSPELQSLKYALSLYTQTTEQLIKTFITSQRQQDLPSQEQPVGEVSVQVDLFSHPGTGEQKVTVKILAANDLRWQTSSAFKPFVEVHLVGPHLSDKKRKWSTKTKAGNWAPKFNETFHFFLGNEGEPEHYELMFQVKDYCFARDDRVVGVGVLQLSSVVDQAGSCAMWVQLGTRLHIDETGLILLRILSQRQTDEVAKDFVRLKTECRYETETVMAASASSQNINRT
What is the function of this protein?
May form part of a signal transduction pathway, transducing the signal from diacylglycerol to effector functions (PubMed:2062851).  One such function could be the release of neurotransmitter from neurons (PubMed:2062851).  Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt, (PubMed:17891142).
What are the official names of this protein?
Phorbol ester/diacylglycerol-binding protein unc-13, Uncoordinated protein 13.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
Protein: IBPB_SHIF8
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_RANMC
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RAPA_ACTP7
Sequence: MFVVGQRWISESENNLGLGIVTASDNRTVTIQFPAAEEERIYALSVAPLTRVQFQKGDRINSVEGWQLDVEEVVENQGFIIYLGKRADSGEEAVLPEMQLDHKVSFSKPQDRLFSAQIDRSDRFALRYRALQHQQAQFQSPLRGMRGIRASLIPHQLHIAKEVGQRVAPRVLLADEVGLGKTIEAGMILQQQLFSGRVERVLVLVPESLQHQWLVEMLRRFNLKFSLFDEERCSDFDKADEDGNDVSENPFDSEALVIASIDWLESSPNRAKQVLASHWDMLIVDEAHHLAWSEDEPSVGYQFVERLSKQTPAVLLLTATPEQLGQESHFARLALLDADRFYDYHSFIAEQKDYKPVADAVATLLNDKPLSHDEQNSIAELLSEKDTEPMFKVINSEKSKENDRLQVRQELIRELIDRHGTSRVLFRNTRQGVKGFPHRVYHQITLEMPSQYTNALKVMGMMGGVTKDDQLYPERLFQRMNPAAKWADFDPRIEWLITFLKNHRDEKILVICKQADTAIALEQILREREAIRSAVFHEKMSIVERDRASAYFAQMEEGAQVLISSSIGSEGRNFQFASNLVLFNLPDNPDLLEQSIGRLDRIGQKNDIQIHVPCFENSMQMVLATWYHQGLNAFEETCPMGAALFREFGEELEGFLKNPQAVGFDEFLVRTFKRQQQLKAELEQGRDRLLELNSNGGEVAQALAEAIAKEDNNPHLVNFALSLFDVIGLEQEDLGEQSIVISPTGHMLVPDFPGIAEDGTTVTFDRQLALMREDVEFLTWDHPMIRNGIDLITSGYIGKSAISLLINKNLPAGTLLLEAIYMVETQAPKGLNLTRFLPPTPVRILLDNKGNDMAAQVSFAGLEKQLKPLNKQMANKIAKMAQADIKKLIGISEQKIAAKLPELIEKASQDADSTLSAELHRLTSLQAVNKNIRSDEIEALEQQRIESLKQIALANWRLDSLRVIVSNKE
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: THIC_SALSV
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARNGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAWHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: IOVO_AQUAU
Sequence: IAIVDCSDYPKPVCSLEYMPLCGSDSKTYSNKCDFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_AGRFC
Sequence: MGSFSVWHWLIVLVIVLVLFGRGKIPELMGDVAKGIKSFKKGMADEDQTPPPADANANAKTVDHKADEIK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UPPP_MARN8
Sequence: MDIFQALFLGLLQGLTEFLPISSSAHLILTPAFFGWEDQGVGFDLSVHVGTLLAVVLYFRRDVFGIARDGLISMGQRKIVGQGALAWYLVIGTIPAGLAGLALLDMIDNELRGASVIFFTTLVFGILLGIADWLPKRQRTMDSLNWKDAVIVGIAQAMALVPGTSRSGVTITAGLFLGMTRETASRFSFLLAIPIIVLASAVKLLEVATSDVIVDWNGFLIGGVTSFLMAITAIHFFLKWLNKVGMWPYVIYRIILAGVIYAVLM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_BACAN
Sequence: MQAKAVARTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SPIKE_ADEP3
Sequence: MGPKKQKRELPEDFDPVYPYDVPQLQINPPFVSGDGFNQSVDGVLSLHIAPPLVFDNTRALTLAFGGGLQLSGKQLVVATEGSGLTTNPDGKLVLKVKSPITLTAEGISLSLGPGLSNSETGLSLQVTAPLQFQGNALTLPLAAGLQNTDGGMGVKLGSGLTTDNSQAVTVQVGNGLQLNGEGQLTVPATAPLVSGSAGISFNYSSNDFVLDNDSLSLRPKAISVTPPLQSTEDTISLNYSNDFSVDNGALTLAPTFKPYTLWTGASPTANVILTNTTTPNGTFFLCLTRVGGLVLGSFALKSSIDLTSMTKKVNFIFDGAGRLQSDSTYKGRFGFRSNDSVIEPTAAGLSPAWLMPSTFIYPRNTSGSSLTSFVYINQTYVHVDIKVNTLSTNGYSLEFNFQNMSFSAPFSTSYGTFCYVPRRTTHRPRHGPFSLRERRHLFQLLQQ
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: GCST_CANLF
Sequence: MQRAMTVVPHLGLRLQALPLALGRPLSRAQDVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHVDSHLHTRRHCSLFDVSHMLQTKILGCDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGIEDDLIVTSTSEGYLYVVSNAGCWDKDLALMQGKVRELQNMGSDVSLEVVDNALLALQGPTATQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPAAAAVRLAAALLENPEVKLAGLAARDSLRLEAGLCLYGSDIDEHTTPVEGSLSWTLGKRRRAAMDFPGASVIIAQLKGKVQRRRVGLTCEGAPVRAHSPILNMEGTVIGTVTSGCPSPCLKKNVAMGYVPSEYSRPGTPLLVEVRRKQQMAVVSKMPFVTTNYYTLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTN_STAAM
Sequence: MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAS5_YEAST
Sequence: MLLRSLTSAFVLSAGLAQAASSSNSSTPSIEIKGNAFFNSESGERFYIRGVDYQPGGSSNLTDPLADASVCDRDVPVLKDLGINTVRVYTVDNSQDHSHCMKLLQENGIYLILDVNTPTSAISRYDPACSYNADYLQNVFATIDTFADYDNVLGFFAGNEVINSVNTTNTATYVKAVVRDMKKYIKARKYRQIPVGYSAADIVANRQLAAEYFNCGDEADARIDMFGVNDYSWCGESSFVVSGYSTKMKLYQDYSVPVFLSEFGCNQVKSSRPFTEIEAIYSTQMSSVFSGGLVYEYSNETNNYGLVQIDGDKVTKLTDFENLKNEYSKVSNPEGNGGYSTSNNYSTCPDYEKGVWEANNTLPAMPSAASAYFTSGAGSPMGTGIATQQSCDAKDDDDEEDDDTSSSSSSSSSSSSSASSSSESSSSTSKASSSSPSASETSLLKSAASATSSSQSSSKSKGAAGIIEIPLIFRALAELYNLVL
What is the function of this protein?
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.  Involved in cell wall biosynthesis and morphogenesis.
What are the official names of this protein?
1,3-beta-glucanosyltransferase GAS5, Glycolipid-anchored surface protein 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 72 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).