PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_ALKOO
Sequence: MNFDTLKIADPEIYEVIQKETKRQRGNIELIASENFVTEAVMEAMGSQLTNKYAEGYPGKRYYGGCEEVDVAEDLARDRLKKLFNAEHANVQPHSGANANIGVYFAILKPGDTVLGMNLSHGGHLTHGSPVNISGTYYNFVDYGVDKETHLINYEEVRRIANEIKPKLIVAGASAFPRKIDFKKFREIADEVGAYLMVDMAHIAGLVAAGLHENPCDYADFVTTTTHKTLRGPRGGAILCKEKYAKMIDKAIFPGLQGGPLMHVIAAKAVSFKEALSPEFKAYQEQVIKNAAKLGEELKSRGFNLVSGGTDNHLLLLDLRNKNITGKDAEKLLDEVGVTVNKNTIPYDPESPFVTSGIRIGTPAVTTRGMKEDDMVTIAEIIGTIIDHPERIDEVSSMVKNLCEKFKLYE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTG_SALSV
Sequence: MSPSDVPINWKRNLTVTWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMAIVMLLMGMAQNIWQFLILRALLGLLGGFIPNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAGGLLADHYGLRPVFFITASVLFICFLLTFFFIRENFLPVSKKEMLHVREVVASLKNPRLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNIAFISGMIASVPGVAALLSAPRLGKLGDKIGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLLVYNSTNQIAGRIFSYNQSFRDIGNVTGPLMGAAISASYGFRAVFCVTAGVVLFNAIYSWNSLRRRRLAIE
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGB4_PEA
Sequence: MGFTEKQEALVNSSWELFKQNPSYSVLFYTIILKKAPAAKGMFSFLKDSAEVVDSPKLQAHAEKVFGMVHDSAIQLRASGEVVLGDVTLGAIHIQKGVIDPHFVVVKEALLDTIKEASGEKWSEELSTAWEIAYEGLASAIKKAMN
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin Lb120-8.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: RL29_WOLPP
Sequence: MDIVKFESESSQGLHELLVNLRKEFVNLAFQKKLGQCNNFSRFSLIRKSIARSLTVLNRRKREGKNA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GLSA_VIBVY
Sequence: MKPTKELLNEILHEVRPLIGRGKVANYIPALARVPAHKLAIAVYTNQGEVIKAGDADEAFSIQSISKALSLTLAMGLYQPDEIWRRVGKEPSGQAFNSLIQLEMEQGIPRNPFINAGAIVVADLLASRLSAPRQRLLEFVRQLSGETHICYDKVVAASEMMHSDRNAAIAYLMRSFGNFENEVIPVLNNYFHACALKMSCVDLAKTFSYLANKGVSVHTDQRVISPVQTKQLNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSERIGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: EYA4_CHICK
Sequence: RKLAFRYRRVKELYNTYKNNIGGLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNIT
What is the function of this protein?
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph).  'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.  Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1.  Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis.  May be involved in development of the eye (By similarity).
What are the official names of this protein?
Eyes absent homolog 4.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NFI_CLOAB
Sequence: MKTVNVHGFEASSKEEFQVIQSSLVKRIKLISDFKEEDIKLCAGVDLAYWTKGEKQYGVCCIIVIDYNTGEIIEKAYDYGEIEVPYMPGFLAFRELPLVIKTVKKLKNEPDIFMFDGNGYLHYNHMGIATHASFFLNKPTIGVAKSYLKVAGVDFEMPESFEGAFKDIVINEEVYGRVLRTKKDVKPIFVSCGNYIDLETCTKICSKLINNDSRLPITVRLADLETHKRRSELS
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_RUEST
Sequence: MAITAAMVKELRESTGAGMMDAKKALVENDGDMEAAVDWLRTKGLAKAAKKSGRTAAEGLVAVVVDGGKGVAVEVNSETDFVAKNGEFQTMVAGIAKAALSVNTVEELAEADLGGKTVATTLTDKIATIGENMTLRRMAKLEGETVVSYVHNAATDGMGKIGVLVALSGGDEAIGKQVAMHIAAVNPAALSEADLDPAIVEKERQVQIDIARESGKPEQVIEKMIEGRMKKFVAESTLLNQQFVVNPDLTVEAAAKEAGATVTGFIRVEVGEGIEVEKEDFAAEVAKAAQG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPI2_MONPV
Sequence: MDIFREIASSMKGKNVFISPASISSVLTILYYGANGSTAEQLSKYVEKEENMDKVSAQNISFKSMNKVYGRYSAVFKDSFLGKIGDKFQTVDFTDCRTIDAINKCVDIFTEGKINPLLDEPLSPDTCLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSIYGEPFNHASVKESFGNFSIIELPYVGDTSMMVILPNKIDGLESIEQNLTDTNFKKWCNSLKATFIDVHIPKFKVIGSYNLVDTLIKLGLTDVFYSTGDYINMCNSDVSVDAMIHKTYIDVNEEYTEAAAATSVLVADCASTVTNEFCADHPFIYVIRHVDGKILFVGRYCSPTTN
What is the function of this protein?
Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes.  Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3.  Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes.  Can also block apoptosis through host tumor necrosis factor (TNF) receptor (By similarity).  The inhibition of host ICE is an example of a 'cross-class' interaction, in which a serpin inhibits a non-serine proteinase.  Also inhibits granzyme B (By similarity).
What are the official names of this protein?
Serine proteinase inhibitor 2, Serp-2, Serpin-2.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
Protein: NRDR_RHILO
Sequence: MRCPYCQSEDTQVKDSRPAEDGAAIRRRRVCPDCGGRFTTFERVQLRDLVVVKKSGRKVPFDRDKLLRSVEIAVRKRNVDPERIDRAVTGIVRQLESSGETEVASGEVGRLVMEALKSLDDVAYVRFASVYRNFREAKDFHELLGELKGDEDKSEEDAG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EFPL_MARMS
Sequence: MPKASEIKKNIAISYDNKTYIVKDIERSVPQGRAGGSLYRMRMYDVVTGRKLDETFKDSDMIDLADLVRRQVMFSYSDGDEFVFMDNEDYTPYSLNKSAIEEEILFVNEETVGIQVVLVNEVPVVIELPTNVELEVIETDPSIKGASATSRNKPAKLSTGAVIQVPEHISTGDRIKVNVEERKFAGRAEK
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SYK_STAEQ
Sequence: MSEEMNDQMQVRRQKLQELIDLGIDPFGHRFNRSSTSSELKEQWDQFSKEELHEKEDESHVSIAGRLMTKRGKGKAGFAHIQDLKGQIQIYVRKDQVGDDQFNIWKMADLGDIIGVEGVMFKTNTGEISVKAKSFTLLSKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTQTFINRSKIIQEMRNYLNKQGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTENMVRHIAQEVFGSAKVQYNDEEIDLESSWKRLHIVDAVKEVTGVDFYNVNSDEEAIRLAKEHDIEITENMKYGHILNEFFEQKVEETLIQPTFIYGHPIEISPLAKKNPNDERFTDRFELFIVGREHANAFTELNDPIDQRQRFEAQLVEKEQGNDEAHDMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLK_HUMAN
Sequence: MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE
What is the function of this protein?
Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination.  Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2.  Negative regulator of the canonical Wnt/beta-catenin signaling pathway.  Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1.  Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes.  Negative regulator of the Notch signaling pathway.  Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1.  Negative regulator of the MYB family of transcription factors.  Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP.  Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself.  Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1.  Upon IL1B stimulus, cooperates with ATF5 to activate the transactivation activity of C/EBP subfamily members.  Phosphorylates ATF5 but also stabilizes ATF5 protein levels in a kinase-independent manner (PubMed:25512613).
What are the official names of this protein?
Serine/threonine-protein kinase NLK, Nemo-like kinase, Protein LAK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear. A smaller fraction is cytoplasmic (By similarity).
Protein: EFTU_LACCB
Sequence: MAEKEHYERTKPHVNIGTIGHVDHGKTTLTAAITKVLSEKGLAKAQDYASIDAAPEEKERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVDYIVVFLNKTDLVDDPELIDLVEMEVRELLSEYDYPGDDIPVIRGSALKALEGDPEQEKVIMELMDTIDEYIPTPVRETDKPFLMPVEDVFTITGRGTVASGRIDRGTVKIGDEVEIIGLKPDVIKSTVTGLEMFRKTLDLGEAGDNVGVLLRGVNREQVERGQVLAKPGSIQLHNKFKGEVYILTKEEGGRHTPFFSNYRPQFYFHTTDVTGVIELPDGVEMVMPGDNVTFEVDLIAPVAIEKGTKFTVREGGRTVGAGVVSEILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDHA_RHIME
Sequence: MTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDAAQITGTHVSMDGGWTAQ
What are the official names of this protein?
D-beta-hydroxybutyrate dehydrogenase, BDH, 3-hydroxybutyrate dehydrogenase, 3-HBDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: EGGR_APLCA
Sequence: ISIVSLFKAITDMLLTEQIYANYFSTPRLRFYPI
What are the official names of this protein?
Egg-releasing peptide.
Protein: PAFA_MYCSS
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDNLIQLVTHDRAGERVLEDLLIDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMCESTTMLKVGTASLVLEMIEAGVPFRDFSLDNPIRAIREVSHDLTGRRPVRLAGGRQASALDIQREYYSRAVDYLQTREPNSQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYNMELSDPKISQLDLAYHDIKRGRGVFDLLQRKGLAARITTDEEIDAAVDTPPQTTRAKLRGEFISAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVKRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: YBEY_BORA1
Sequence: MKAGEPGLALAVQYAVAEPRLPRWRLRRWAGYALAGAAADGLIDFQAAELNVRLVGQAEGRRLNADFRGRDYATNVLTFEYGVDPLGTARGDIVICAPVLAREAREQKKSFVDHATHLTIHGVLHALGYDHIKVREAKRMEALETRILARMGIADPYLLAD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC30_MYCTU
Sequence: MVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKGRHRAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB30.
What are the official names of this protein?
Ribonuclease VapC30, RNase VapC30, Toxin VapC30.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: DNAA_BORT9
Sequence: MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDESIKISAPNSFHKNQVEKRFSKRIKEILTEKGHNTINVEFINPPKEPKTHSMELKNTSLKDISIQQDSPEKRTILNTHTKNIIEHTKHYVIKEDIHTKYRNPFLKKKYTFENFIIGPNNKLAYNASLSIAKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRHLDMLLIDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAEEDGIKVPKNILNLVAKKVTTNIRDLEAAVTKLKAHIDLEDIEIDTSIVDKIIKEIIAYENDKTNTNNTINIESIKKVILRELKLTNKDIEGNSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNKINKN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_THETH
Sequence: MPKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSKRGGKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: YIDD_BART1
Sequence: MLKSQFQQKKMTRNYTGAWQKTPGRLLGIFLIRFYQITLSSLIGNQCRHAPTCSEYIYEAIARHGLWAGAWMGLFRIMRCGPFGTDGFDPVPPSLGHSCCFYKPWRYWKISDKHNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL24_MYXXD
Sequence: MQKLKVGDTIQVMAGAEASEKNPATKRGKVLKIDREAERVTVEGLRLVKRHMKKTPQSPEGGIVEKPGTIALANVQVVCAKCDKPTRVGIRTEGEEGKKKRFCKNCDALID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: DCUP_YERPG
Sequence: MNELKNDRYLRALLRQPVDMTPVWMMRQAGRYLPEYKATRAIAGDFMSLCKNAELACEVTMQPLRRYPLDAAILFSDILTIPDAMGLGLYFETGEGPRFQSPITCRADVEKLPIPDPEQELGYVMNAVRTIRRELAGSVPLIGFSGSPWTLATYMVEGGSSKAFTKLKKMMYAEPQTLHLLLDKLADSVILYLNAQIKAGAQSVMIFDTWGGVLTGRDYHEFSLNYMHKIVDGLIRENEGRRVPVTLFTKGGGPWLEAMAATGCDALGLDWTTDIADARRRVGDKVALQGNMDPSVLYAPPARIEQEVSTILASFGQGEGHVFNLGHGIHQDVPPAHAGAFVNAVHALSRPYHQK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_PROM5
Sequence: MKKHLLFLGPPGAGKGTQAAYLSEANSYLHLSTGELLRKEIDLDTYLGKQVKDIMNKGELVSDQLVLEIVNKNLSKDNKGWILDGYPRNLSQVNSLNEVLMNINQPLEIVFYLDVPDEVLIKRLLLRGRKDDNEETIKTRLKIYKETTEPLIEYYKNLSLLEYINADGDLKTISNDIKQKMA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_PAEAT
Sequence: MNRASLEKRPDEVATMFDDVAPKYDVVNDVLSMGQTRRWRRIVVDAMDVKVGQKVLDLAAGTGTSSEPYADAGVDVVACDFSLGMLKVGKRRRPDIDFIAGDATNLPFADNSFDASTISFGLRNVVEPRKALEEMLRVTKPGGRLVIAEFSHPVVPLWRNLYTEYLMRALPAIATKVSSNPDAYVYLAESIRAWPDQDHLAQWLSDAGWTDITYRNLSGGIVAVHRAQKPDEHRESVPVAKLRRQIKPRHQAG
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: IAA16_ARATH
Sequence: MINFEATELRLGLPGGNHGGEMAGKNNGKRGFSETVDLKLNLSSTAMDSVSKVDLENMKEKVVKPPAKAQVVGWPPVRSFRKNVMSGQKPTTGDATEGNDKTSGSSGATSSASACATVAYVKVSMDGAPYLRKIDLKLYKTYQDLSNALSKMFSSFTIGNYGPQGMKDFMNESKLIDLLNGSDYVPTYEDKDGDWMLVGDVPWEMFVDSCKRIRIMKGSEAIGLAPRALEKCKNRS
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA16, Indoleacetic acid-induced protein 16.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4Y1_PANTR
Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQRFIKIDGKVRVDVTYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITVEEAKYKLCKVRKITVGVKGIPHLVTHDARTIRYPDPVIKVNDTVQIDLGTGKIINFIKFDTGNLCMVIGGANLGRVGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGNGNKPWISLPRGKGIRLTVAAERDKRLATKQSSG
What are the official names of this protein?
40S ribosomal protein S4, Y isoform 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: FTSW_NITEU
Sequence: MMSPSTSAPHNQPIQPELDVLLVSTVLLLLGLGLVMVYSASIAIAEAKFGEGSSYYFLARQASYILAGIAVGIGCFRIPLRWWQAYSHYLLGLGILLLLVVLIPGISHEINGSRRWIPLGITSFQPSELMKLIILIFTADYVVRKAAFKDHFFKGFLPILALLTIVSLLLLMEPDLGATVVIAAIVLSIMFMNGMSLKMFFGLICLVPVLLALLIIIEPYRMDRINAIFDPWNDPFDKGYQLTHALIAFGLGEWWGVGLGSSVEKLNYLPEAHTDFMFAVLAEELGFAGVVTVISLFFFLLVRIFKVGRTAARLGDQFGSLVAQGIGVWLGLQAFINMGVNMGLLPTKGLTLPFMSYGGSSIVINSIAIAILLRIDWENRLKRRGLNA
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: FTSH_CLOP1
Sequence: MFKDKKMLKYIVIYSIIAFGILLTFNMVKDEMLYEKVDYSTFMQMLDKKEVKSVNFSGNQIEITPSDSSNLKGKILYTTNPAVAGITQPELIKDLTVAGVEFNVTKPENYQLLGLLMSWVFPLILIFFVGRMMFSKMNNKMGGGVMSFGKNNAKLYAENETGITFKDVAGQDEAKESLVEIVDFLHDTRKYVEIGAKLPKGALLVGPPGTGKTLLAKAVAGEAKVPFFSMSGSDFVEMFVGMGAARVRDLFKQAEEKAPCIVFIDEIDAIGKSRDGAIQGNDEREQTLNQLLTEMDGFDSSKGVVILAATNRPEVLDKALLRPGRFDRRIIVDRPDLIGREEILKVHSRDVKLSDDVSLEEIAKSTPGAVGADLANIVNEAALRAVKHGRKFVIQEDLDEAVEVIIAGQEKRDRILSPKEKKIVAYHEVGHALVAALLNNTDPVHKITIVPRTMGALGYTMQLPEEEKYLVSKEEMIDQISVMLGGRAAEEVVFNSITTGASNDIERATQSARNMITIYGMSERFDMMALEAMSNRYLDGRPVRNCSETTAAIADEEVLQVIKKAHEKSIKILIENRELLDEITGVLLDKETIMGDEFMEIVYGKYPEKREADEKAKKEIQSLREQALAKRKEKEEAIKKAREEALRLEEEQRKQDELKAMIEAQEEAAKLARANNEANNDALDSSKENEEVKSNVNDGATEEKKDDSSTNNKVDGE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: DADA_SALSV
Sequence: MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTFRFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMVVRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYRSDFTPTRPQRLHSAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.