PharMolix/UniProtQA huggingface dataset:
Protein: GLMM_CAMHC
Sequence: MKLFGTDGVRGKAGNFLTAELALRLAMAAGVYFRKNSLTNMILVGKDTRRSGYMIETAIVAGLTSVGFNVRQIGPMPTPAVAFLTEDMRCDAGIMISASHNPYYDNGIKFFDRTGFKLDEKEEAEIEKIYFSDKIINEARKQMMEIGTAKRVDDVIGRYIVHIKNSFPRSETLHNLRVVIDTANGASYKVAPTIFKELGAETIVLANEPNGKNINENCGALFPQNLANEVRRLRADVGFAFDGDADRLVVVDENGEIIHGDILLGILASYLKESGELANDKIVATVMSNKALDDFLAKIGISVIRTNVGDKFVLEKMREIGSNFGGEQSGHVIFGSFAKTGDGIVSALQFSACMIKMHKKSSEISKMIKPYPQILRNLKIKNKKPLDKIKGLDEFEKNIQKDGIRTLFRYSGTENLIRLLLEGKNEKLLNKKMDEAEEFFSKALND
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GLMM_BURA4
Sequence: MGRRYFGTDGIRGTVGEAPITPDFVLRLGYAAGKVLAGTADVAAGARPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYQDNGIKFFSADGNKLPDETEAAIEAWLDKPLECASSDRLGKARRLEDAAGRYIEFCKSTFPAAYDLRGLKLVIDCAHGAAYQIAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALVRAVRANHADLGIALDGDADRLQVVDSTGRLYNGDELLYVLVKDRIATAGKVDGAVGTLMTNLAVEVALQREGVPFVRAAVGDRYVLEQLRERGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSDRTLAQMLDGVTLFPQKLINVRMKPGADWKGSASIRAAIDAAEGALAGSGRVLIRASGTEPVLRVMVEAQQAADATRHAEAIADAVRIATS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SSN8_YEAST
Sequence: MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEARTLWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.  The SSN3/SRB10 and SSN8/SRB11 kinase-cyclin pair may also positively and negatively regulate numerous transcriptional activators in response to changes in nutritional and physiological conditions.
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit, Suppressor of RNA polymerase B 11.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
Protein: RL36_ANOFW
Sequence: MKVRPSVKPICEKCKVIRRRGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: FLGI_ESCF3
Sequence: MIKFLSTFMLLLVTTVVQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPAGTNMQLKNVAAVMVTASLPPFARQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAIIERELPSQFGAGNTLNLQLNDEDFAMAQQIADTINRARGYGSATALDSRTIQVNVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: BAR1_CAEEL
Sequence: MDLDPNLVINHDDTNLSEASFTMEQHTSSYSDIHMGSTPCTGHRKVDMWRNHNFDSGFQTMNHSEAPSIISSLHPSSHLSGMSSMADYEPIPTLSDQQKQKFDGITQNQADGQYNTVRAIPELTMLMKDQDNEVVHKAVILMQNIAKMECDPMRRQNEARIVDPRVIFTLRDLLRDKVEFPNIIRCTLGTFFHICNRQEGIDLVTRAIAEQPDIIPNLIRHIGTYPSSIYKYAILTMHSILSDKQRGGQSVIIARQQDAITHVTPWLEAEKSEKLLPVIVDLIRVLCEKNTEQKIKFVKMGGPQKLLMLLQHRVYENLLWRTTQLLKTFSNFDAPNLVAFGGRQILANLLSHGSPRLVQSTLETLRNISDVPSKIKEDLLLKSLLELVNSRNTTIRLYSAQIMSNLVANNRHNKEFMCGNNGVVILVRALTIATKEMGDLRDKEAQQMEDYIESLICTLRHLCVGHPMSDKVQAFVFRDPALFLHKLLTMRPVLLKHTLSLLLKVVSQHALLAPFRSCRIGDKGFVEQLIHILRVACTQLNVQESIEGVRVKDIIHLCIQILRWITRDQDILNEVVFFLQTPENSRMGDGHTLPIFVLQKANVEENTKSSALALIYNLMHHEQMANVLDRDDVLVKMLQNVQMQSQTHPELASLANNILKMMYEKREKTRNTLPRYNSYLESQFGHMSMTTPRSEALNSSGEVCEGAGEQWSTPLTDDTMMDSYCNSSGRDSSKPYNSPMYHSPPAMYPEYSIGPPETYLDPHATASCYPRPTPPQYNSYDRSPPVYNDLPSNPGPSSHSSDYYPSRNSRF
What is the function of this protein?
Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development (PubMed:10952315).  Functions as a transcriptional activator but is dependent on the interaction with pop-1 (PubMed:10952315).  Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses (PubMed:15820693).  Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling (PubMed:9834184, PubMed:15905404).  Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectodermal cell P12 specification, movement, body length, male tail development and dauer induction (PubMed:9716532, PubMed:9834184, PubMed:11063687, PubMed:11560894, PubMed:12441291, PubMed:15905404).  Functionally redundant to wrm-1 and hmp-2 (PubMed:11560894).  In the intestine, plays a role in probiotic-mediated protection against infections by pathogens such as S. enterica (PubMed:35263319).
What are the official names of this protein?
Beta-catenin/armadillo-related protein 1, Protruding vulva protein 1, Suppressor of polyray 1.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cell junction. Note=Mostly cytoplasmic.
Protein: RL18_METM6
Sequence: MAKNAKFRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVIAQLMAYDEKGDVVLVSAHSRELVKMGYKGHCGNLPAAYLTGLLLGKKAVKEGAEEAILDKGLHRATKGAAIFAVLKGALDAGMDIPHGDEIIADEERLNGTHVKNYAESLKEDADAYKKQFSKYLEKGLNPEDLPEHVEELKEKILNL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IRX3_XENTR
Sequence: MSFPQLGYQYIRPLYPSDRQNVGGTRSGTELSPAGTLSNVLSSVYGTPYAAAAAAQAYGAFLPYSAELPIFPQLGSQYEMKDSPGVQHAAFSHPHAAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSDHEEDKHEDDEEIDLENIDTEDIESKEDLDDPDTDIHSDSKTDARSDSEASDGFEDLNAPEDRLLKSVVGQRQVLNEEPQDKCALSSDAKASQPACEQIKLDRIPSSPPLENNIPAAHKPKIWSLAETATTPDNPRRSPNTGGSVNTQNLIAQHRLIASPGSRFQGWTGRAFSAQQLSLLNSAHFLQGLSVSHTALGSGTASFPKAAEPKHSTDSLTDRSSTVDIEKKIPVLNTAFQPVQRRSQNQLDAAMILSALSSS
What is the function of this protein?
Acts partially redundantly with other irx members in neural patterning.  Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord.  Both up-regulates and down-regulates gene expression during neural development.  Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state.  Also up-regulates repressors that prevent neuronal differentiation.  Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling.  Subsequently required for proper formation of the intermediate tubule segment of the pronephros.
What are the official names of this protein?
Iroquois-class homeodomain protein irx-3, Iroquois homeobox protein 3.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KCNN1_RAT
Sequence: MSSRSHNGSVGRPLGSGPGFLGWEPVDPEAGRPRQPTQGPGLQMMAKGQPAGLSPSGPRGHSQAQEEEEEEEDEDRPGSGKPPTVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELAVCAIHPVPGHYRFTWTARLAFSLVPSAAEADVDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSISSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQSRVRKHQRKFLQAIHQAQKLRTVKIEQGKVNDQANTLADLAKAQSIAYEVVSELQAQQEELEARLAALESRLDVLGASLQALPSLIAQAICPLPPPWPGPSHLTTAAQSPQSHWLPTTASDCG
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:8781233).  Activation is followed by membrane hyperpolarization (By similarity).  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity).
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 1, SK1, SKCa 1, SKCa1, KCa2.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.1/KCNN1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UFOG_GENTR
Sequence: MSPVSHVAVLAFPFGTHAAPLLTLVNRLAASAPDIIFSFFSTSSSITTIFSPTNLISIGSNIKPYAVWDGSPEGFVFSGNPREPIEYFLNAAPDNFDKAMKKAVEDTGVNISCLLTDAFLWFAADFSEKIGVPWIPVWTAASCSLCLHVYTDEIRSRFAEFDIAEKAEKTIDFIPGLSAISFSDLPEELIMEDSQSIFALTLHNMGLKLHKATAVAVNSFEEIDPIITNHLRSTNQLNILNIGPLQTLSSSIPPEDNECLKWLQTQKESSVVYLSFGTVINPPPNEMAALASTLESRKIPFLWSLRDEARKHLPENFIDRTSTFGKIVSWAPQLHVLENPAIGVFVTHCGWNSTLESIFCRVPVIGRPFFGDQKVNARMVEDVWKIGVGVKGGVFTEDETTRVLELVLFSDKGKEMRQNVGRLKEKAKDAVKANGSSTRNFESLLAAFNKLDS
What is the function of this protein?
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments (PubMed:8819318).  Anthocyanidins are the preferred substrates, while flavonols are only a minor substrate in vitro (PubMed:8819318).
What are the official names of this protein?
Anthocyanidin 3-O-glucosyltransferase, Flavonol 3-O-glucosyltransferase, UDP-glucose flavonoid 3-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MURQ_SALSV
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: PQSH_PSEAE
Sequence: MTVLIQGAGIAGLALAREFTKAGIDWLLVERASEIRPIGTGITLASNALTALSSTLDLDRLFRRGMPLAGINVYAHDGSMLMSMPSSLGGNSRGGLALQRHELHAALLEGLDESRIRVGVSIVQILDGLDHERVTLSDGTVHDCSLVVGADGIRSSVRRYVWPEATLRHSGETCWRLVVPHRLEDAELAGEVWGHGKRLGFIQISPREMYVYATLKVRREEPEDEEGFVTPQRLAAHYADFDGIGASIARLIPSATTLVHNDLEELAGASWCRGRVVLIGDAAHAMTPNLGQGAAMALEDAFLLARLWCLAPRAETLILFQQQREARIEFIRKQSWIVGRLGQWESPWSVWLRNTLVRLVPNASRRRLHQRLFTGVGEMAAQ
What is the function of this protein?
Involved in the terminal step of the biosynthesis of quinolone which in addition to serve as a potent signal for quorum sensing, chelates iron and promotes the formation of membrane vesicles (MVs).  Catalyzes the hydroxylation of 2-heptyl-4-quinolone (C7-HHQ) to yield 2-heptyl-3-hydroxy-4-quinolone (PQS).
What are the official names of this protein?
2-heptyl-3-hydroxy-4(1H)-quinolone synthase, 2-heptyl-3,4-dihydroxyquinoline synthase.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxybenzoate 6-hydroxylase family.
Protein: PURA_CAMFF
Sequence: MTKADLIVGIQWGDEGKGKIVDMLSQNYDVVCRSGGGHNAGHTIWVDGMRYALHLVPSGILHKNIINIIGNGVVVNPEVLISEMAQFDHLEGRFFISDRAHLNLAHHSLIDQAKERLKGDKAIGTTGKGIGPAYSDKISRSGHRVGELLDPKALCESLMKDFESNKPYFDALSIEIPPKDKILADLVRFKDVLAPFITNTTELLWRAMDDNKKVLLEGAQGTLLDIDHGTYPYVTSSNTVSAGACTGLGLSPKSIGKVIGIIKAYSTRVGNGAFPTEDLGSDGENLCEIGKEFGTTTGRKRRCGWLDVVGIKYSSRLNGVDTYALMKLDVLDGFKNVKICKAYEYKGEVIDYFPSDLQNATPIYEELEGWDSINGIKKYEDLPLNARKYIERIEELTGVKIGFISTSPERNDTIVR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SF3B1_MOUSE
Sequence: MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGELKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAKGSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYDLDYIL
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex.  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.  Together with other U2 snRNP complex components may also play a role in the selective processing of microRNAs (miRNAs) from the long primary miRNA transcript, pri-miR-17-92 (PubMed:26255770).  May also be involved in the assembly of the 'E' complex.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Splicing factor 3B subunit 1, Pre-mRNA-splicing factor SF3b 155 kDa subunit, SF3b155, Spliceosome-associated protein 155, SAP 155.
What is the protein family that this protein belongs to?
Belongs to the SF3B1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm.
Protein: NECK2_BPT4
Sequence: MATYDKNLFAKLENRTGYSQTNETEILNPYVNFNHYKNSQILADVLVAESIQMRGVECYYVPREYVSPDLIFGEDLKNKFTKAWKFAAYLNSFEGYEGAKSFFSNFGMQVQDEVTLSINPNLFKHQVNGKEPKEGDLIYFPMDNSLFEINWVEPYDPFYQLGQNAIRKITAGKFIYSGEEINPVLQKNEGINIPEFSELELNAVRNLNGIHDINIDQYAEVDQINSEAKEYVEPYVVVNNRGKSFESSPFDNDFMD
What is the function of this protein?
Plays a role in the association of the virion head and tail after packaging of viral DNA within the head.  Together with gp14, forms a neck at the portal vertex of the head to be ready for the tail attachment.
What are the official names of this protein?
Neck protein gp14, Gene product 14, gp14.
What are the subcellular locations of this protein?
Virion.
Protein: METE_BACP2
Sequence: MTIVKTSNLGFPRIGLNREWKKALESYWKGQTDRETLLSTLDEQFLTAIKTQIDQQIDVVPSGDFTFYDHVLDTAVMFNWIPERFRSLKDPLDTYFAIARGTKDAVSSEMTKWFNTNYHYIVPEYEKSTEFKLTHNKPLEAYEKVKKAFGVETKPVVLGLYTFVSLSKGYEPNEVKEIQQRLIPLYTQLLKELEEAGVKWVQIDEPALVTASYEDVKAVKEIYQTITEAVPALNILLQTYFDSVDAYEELVTYPVEAIGLDFVHDQGRNLDQVKKHGFPKDKILAAGVIDGRNIWRSDLGERLTFVSEVIAGAQPKEVWLQPSSSLLHVPVAKHPSEQLEEKLLNGLSYATEKLAELTTLKEGLTKGAAAIEAAINEAEQALLTLKEFAKGTNADFTAERNNLSSKDFKRPVAFEERLRIQNESLELPLLPTTTIGSFPQSAEVRSARQKWRKNEWTNAEYDEFIKKETKRWIDIQEEIGLDVLVHGEFERTDMVEYFGEKLAGFAFTKFAWVQSYGSRCVKPPIIYGDVEFTAPMTVKETVYAQSLTEKKVKGMLTGPVTILNWSFPRTDISRKDIAFQIAFALRKEVEALEEAGIQVIQVDEPALREGLPLKESDWADYLNWAAESFRLSTSSVQNETQIHTHMCYSNFEDIVDTIEDLDADVITIEHSRSHGGFLDYLEKHPYLKGLGLGVYDIHSPRVPSVEEMSQIIDDALNVCPTDRFWVNPDCGLKTRQEPETIAALKNMVTAAEVARKKLAQHA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: HRCA_MESH7
Sequence: MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFLSFDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKKITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLILDKEISRAKLVDLLYIIEKKSIWEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIKLLEDFLSNKSKIRKG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: EXO84_NEUCR
Sequence: MSEERSKISLRSGGKRKNRPTISAPRQISAPIPQDNGMPQPPPEATMADEPRMTRPRPPPPGGKTSDLVKKRYSTRFGNMPTDFDPSSNPMPALPDLEKYMQAQVGSPPSRGGDAGGLGPMGREPPRVDIRTLRDPNFAPEQYVAEVLGEATEDEIRDYEDALKQLKARAAADLQQNVYQNRTQFIKISKEAEKLKGEMRTLRNLMLELKTNTTALRASSNSADSSGSLGPEFSTGLSKRDRRSSITDRTALWSAQMQALYKSVEGSQKFLPNSQGRHVVQNAGPWIELDNATYKSRRSMQIFLLNDHLLIASRKKRKIDGPGADARGPMTKLVADRCWHLLDVEVVDMAGTGDSSNGRNKLADAIMVRGGGQNESFIYRTEKPEDPEKTTLILNIRKTVEELRRNLQSERDATNKAKETINYFASRDPGLLQKTELLETLSDIKDMLIEVDGKQQNLRWVESQMDELDINIALQQIEPAVARIEMLKNLASGLKNNMIAQDFISFKVDERCARLATLVVRELVNSHNDQKKTKRNVTWLVRLGFEDRAREAYLEARSEVIQKRSRQCIFQGDLHLYIWEISFVYFMVIRNTVICFQSCFPPPMMSACVKWAKEEVDAFNVILARQLSSAEEGGEVWTECVNRAKEHASMLSDVGLDFRNLVGRNVGTSTTVPGGASAGLGLS
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis.  Also involved in assembly of the spliceosome (By similarity).
What are the official names of this protein?
Exocyst complex component exo84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of exo84 requires actin cables (By similarity).
Protein: RS12_STRTD
Sequence: MPTINQLVRKPRQSKVVKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQSRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL29_MARSD
Sequence: MKAKELRELDNAALNEKLAEARQELFNLRFQHATAQLENTQRLSDVKKDIAKILTVQREKELGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PLINH_HALLA
Sequence: ECTIGDSCVVHRHCRECRCPRGRAMCDREHHKPPHCSCHIH
What is the function of this protein?
Binds to calcite crystals in the shell and inhibits further shell growth at the binding site.
What are the official names of this protein?
Perlinhibin.
Protein: ORF1_TOTV
Sequence: MSFISRLNTSLEEEAFHKQVADSQWVCSVDTGSGIINSDPTLDFKICPKTGGAISVLSVSWQNNSPQLVPGHYLLRSGTWPITGVKLSGLLVHRSIRLETTRKLLEAQRISVSQQASSSSAAGAAGKQPQVTLTQLQEELDEAKTRLALKEKELLEALSEISKLRLQLSNQLSNDDVFSGWTEEGPK
What are the official names of this protein?
Uncharacterized protein ORF1.
Protein: SPY1_CEREL
Sequence: MDPQNQHGSGSSLVVIQQPALDNRQRLDYEREIQPAAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKHERTHEIIPINVNNNYEHRPTSHLGHTGLSNNTRGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPIPGHRSERAIRTQPKQLIVDDLKGSLKEDLTQHKFICEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQSQCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCKGCYDWIHRPGCRCENSNTVYCKLESCSSRGLGKPS
What is the function of this protein?
Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity).
What are the official names of this protein?
Protein sprouty homolog 1, Spry-1.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Protein: RL28_STAA9
Sequence: MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GCSH_DEIGD
Sequence: MQTPPELKYAPSHEWLAPDGTVGISDFAQDQLGDVVYVELPEVGRVVTAGETVAVVESVKTASDIYAPASGTIVAVNEQLSGSPELVNQSPYTDGWLFRLDVTEESGELMDAEAYAAANG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.