PharMolix/UniProtQA huggingface dataset:
Protein: EFP_AMOA5
Sequence: MATTSDFRNGLCIEFNNDLYTIVEFQHVKPGKGGAFVRTKLKSLTNGKVIDNTFNSGVKITTARIERKTYQFLYKDGAGYHLMDNNTFEQLDLDEKAIQNPLLIKEGQELDVLFHQETGNFIGCELPPFVELKVTYTEPGLKGDTATRALKPATLETGLQIQVPLFIDNDEIIKIDTRTIAYVERVKTDI
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLP24_YARLI
Sequence: MRVYNCHFCSSPVYPGKGIMFVRNDSKEFRFCRSKCHKNFKMKRNPRKLRWTKAFRKAAGKEMVVDSTLAFSARRDVPVRYNRDLVEKTLEAMEKVEEIRLKRERAFYKNRMRGNKAAQLEEDRKLVEAHPELLREREVELRRMQEAGEDDDDEDMSEMEVSEEEESEEEREKVEIALKSKSKRKMRA
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  Ensures the docking of YALI0_B00990g/NOG1 to pre-60S particles.  Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
What are the official names of this protein?
Ribosome biogenesis protein RLP24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: RUVC_THEM4
Sequence: MKIIGIDPGYGILGYGVLEKSGNKISHITHGVITTDKELSMYKRLQVIYEEFLRLLKEYSPDACAIESLFFYKNVKTAIRVGEARGVILLATSQMDLPLYEFTPYQVKNNITGYGHSDKKQVQKMVKMLLNLDKIPRPDDAADALAVAWCLAVETRF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RS12_RHILO
Sequence: MPTVNQLIRKPRIAPVKRNKVPAMQQNPQKRGVCTRVYTTTPKKPNSALRKVAKIRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NOL7_HUMAN
Sequence: MVQLRPRASRAPASAEAMVDEGQLASEEEEAEHGLLLGQPSSGAAAEPLEEDEEGDDEFDDEAPEELTFASAQAEAREEERRVRETVRRDKTLLKEKRKRREELFIEQKKRKLLPDTILEKLTTASQTNIKKSPGKVKEVNLQKKNEDCEKGNDSKKVKVQKVQSVSQNKSYLAVRLKDQDLRDSRQQAAQAFIHNSLYGPGTNRTTVNKFLSLANKRLPVKRAAVQFLNNAWGIQKKQNAKRFKRRWMVRKMKTKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 7, Nucleolar protein of 27 kDa.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UPPP_STRPZ
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIIIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPD_BARQU
Sequence: MTNLTQLEMIIEKAFDDRDSIKTTTKGEIRESVEHALNLLDKGEIRVAERQKNGQWHVHQWLKKAVLLFFRLNPMQIIAGGVNGTYWWDKVPSKFSNWQETDFKKANFRSVPGTIVRHSAYIAPNVILMPSFVNLGAFIDEGTMVDTWATVGSCAQIGKHVHLSGGVGLGGVLEPLQANPTIIEDHCFIGARSEVVEGCIIREGAVLGMGVFIGKSTKIIDRTTGEVFIGEVPAYSVVVPGSLPGKPLPNGEVGPNLYCAVIVKRVDQKTREKTSINDLLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y355_BACHK
Sequence: MKKYWHKLSFLQKNVLLTVLVILTLVGTMGALSFNMFQNSMMSIFERHSFETGDTVLHKLDEEIVRDVTKDPVAQREKREKLTEKLDEATEELNSVGQTYIVGAKKNEKGELLIVDLSTDLANVVEVRPGEYYKQPDLWMEAYDKVMSTKKANMTVVYEDLLGTWVTILEPIKDGEGNIVAIVAADVDASIVPSTKEKFIIQGLMFICISVLIATVIQFLIVRNALAPLRDLREGLRRVGEGDLNIKLEERSDDIGIINSYFNNTIEKFKGIIDKVKQTAEQVSSSSQELSVSTKENSMAVQEIVSSMVELRAGAQLQETSVPQYLGIVYEVEDKMEEITNAAKQMEKVSEGIEHHSVKGNGVTKQAINQMNIIQNAVQDLSSIIYSLEVRSKEISDIVTVITSISNQTNSLALHATIEASRAEETGEGFAVVADEVRKLAEQMEASAKDIANLIGETQAGTEEAVVSIRKASKEVESGMKLVEMNGAFFEEISKSAQSVTNQVRVVSSNSSDILQNSQNIVRVVNELSLIANTYTNSSSNVEESMKEQEMSVQDIAELASSLSWLSQELQELIGEFKS
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
What are the official names of this protein?
Probable methyl-accepting chemotaxis protein BT9727_0355.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXC_BORPE
Sequence: MFRQRSIQNLVRTIGVGVHSGRRVELTLRPAEANTGIVFHRVDLPQVVDLPASAIGVGDTRMASVLQQGNVRVSTVEHLMSALAGLGIDNLHVDLTAEEVPIMDGSAATFVYLLRSAGIVEQNAPKRFIRVLKPIEVREGEGRNEKWARLEPHEGFALAFSIDFRHPAIDSTANFAEIDFATHSYVREIARARTFGFVNEVEALRSMGLARGGSLDNAIVMDEFRVLNSDGLRYDDEFVKHKILDAIGDLYLLGKPLVARYVAYKSGHALNNQLARALLEQQDAWELVTYESQAEAPQAFRHEWKLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: HFLD_HAEI8
Sequence: MKNYHDIVLALAGVCQSAKLVHQLATESRADSDTFLTALNSLFITQPQRIEDVFGGEVRHLKLGLETLIHQLNAQGDQNLTRYWLSLLALEGKLSKNSDAKQTLGNRISRLKEQEIHYARDSETMLSIMANIYSDIISPLGKKIHILGSPDYLRQELVQNKIRAVLLAGIRSAVLWKQMGGTKWQILFFRRKLLATAKQIYSSIY
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMKL_PSEF5
Sequence: MSDRYELFLTCPKGLEGLLIEEAVGLGLEQAREHTSAVRGMADMETAYRLCLWSRLANRVLLVLKRFPMKDAEDLYHGVLDVDWQDHMLADGTLAVEFSGHGSGIDNTHFGALKVKDAIVDKLRTPTGERPSVDKLNPDLRIHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAILIRSGWPRIAAEGGALADPMCGVGTFLVEAAMIAADIAPNLKREQWGFTAWLGHVPALWRKLHDEALARAQAGLAKPPLWIRGYEADPRLIQPGRNNVERAGLSEWIKIYQGEVGTFEPRPDQNQKGLVICNPPYGERLGDEASLLYLYQNLGGRLRQACLNWEAAVFTGAPDLGKRMGIRSHKQYSFWNGALPCKLLLIKVLPDQFVTGERRTAEQRQVEREQAQAAADEAPVRQYNKNGNPIKPAPAPAPVVEQARLSEGGQMFANRLQKNLKQLGKWAKREGIECYRVYDADMPEYSLAIDLYQDWVHVQEYAAPKSVDPEKAQARLFDALAAIPQALNVDKSRVVIKRRERQSGTKQYERQSAQGQFTEVREGGIKLLVNLTDYLDTGLFLDHRPMRMRIQQEAAGKRFLNLFCYTATASVHAAKGGARSTTSVDLSKTYLDWARRNFSLNGFSDKNRLEQGDVMAWLDSCRDEFDLIFIDPPTFSNSKRMEGVFDVQRDQVQLLDLAMARLAPGGVLYFSNNFRKFQLDENLAARYQIEEITAKTIDPDFARNGKIHRAWKVTAR
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOW_HYDTT
Sequence: MRSVRMRAELDGMHVSGAERVIPHYELEKVVMELLKRPKRYDKIVITIERVENLETIPKSLPIKSHDFADVEQAHEFVIKKLKEIGIEESITQKALKLLTEGPNPKGGNMRGAVLMDPVSGERLEPDQERGIRTTRIDWRNRTAIKEALRERGIKKFYLERLIDALAIATKNIHCGVIAEICWSDDPEYTTGYIASKEFGYIRIKPMKEEHTPTGGRVYFVKRESLQELIECLERKVMLIEQLL
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: RECF_CHLPM
Sequence: MRLRSIQFENFRNHRSFSFEPEDGINLIYGQNGSGKTSILEGIHYCALTKGFVSAADGECLSFSAGYFLLTALFESSSGIETAVRLSYTKESGKKLQIDGNELKPFSLHIGSIPCISFSPPEIVIVSGPPGERRRFLDNAVCQSDRRYLDNLLIYRRLLQQRNALLQQLSQSPGKDRSMLQLWSENLASSAASVTAGRVRFLAEFHPFVELLHRDLSGGQMPSIEYRSTIGRLLEPVPESELRERFLQRFQENEQQEILRGQTLSGPHRDELIFLSDGRESKRYSSQGQQRTFLISLKLALFQYFNEKIGETPICLLDDIFSELDGKRTAAVLDILEGCGQTLISSADLKNHPGSAVHHLQTTPSTRNSEV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_ONYPE
Sequence: MKGDYWRTHCIMDCSLLVFALICGSIIGYFLYSFFNQKKLEEKKQAFDDKLKEKEKDLQQREQEMMRNAKIEITSLRQKLELDLEQRTNTIVDLESKNNRREELFNNRTESLNKREEHLDSEQQIISHTKKNLEQQIKEQETILNTQKQQLEKIASLTQDQARQIIMKETRDQTTYEMMSYIKQEEEKAKSEASKKAKTLLVLAMQKYAGDITGEKNISVVNIPNEDMKGRIIGRQGRNIKSLEVLTGVDLIIDESPCTIILSSFDPIRREIAKKTLEFLVSDGRIHPSRIEKALETSTIEVDNFIKEMGEEAAFITKIGEVHPDLIKILGKLHFRISYSQNVLKHSLEVAFLAGKLASEIGENEILARRAGLFHDIGKALDHEMEGSHVEIGVFIASKYKEKKEVIDAIASHHEDQEPQSIIAVLVAIADTLSSARPGARKESVENYIQRLTKLETIANATEGVAKSYAIQAGREIRVIVEPDKIADNFIFQTARTIKEQIEKDISYNGVIKVTVIRETRAVEMAKL
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COBQ_MYCTA
Sequence: MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: VLMC_LECSP
Sequence: MIFTQPSFVPALPSPLPLGETIGDFCMSERLAKVGNDAVEEQPIPFIDAAIDKSWTTDEINTRVAQLTRALATEWNIAPGEKWHKQVAVLASNCVSIFMDTLILTWAIHRLGGGCLMLQPTSSVEEMAAHIDHVPPFAMFVTLDLVTLGQETIQKSSQSADLPFYKFSKVYGPPAKNAPDTSNVKSLDALLEKSKDQAPIEKLLLAEGEGSKRVAYYCTTSGTGGFQRIVAITHENIIASILQAGLFTGITKEKSEIALVFTPFNHIYGLLTAHTLMWLGHSTVIHRGFNMLEVLMSIPKRRITTLYLVPPIINAMSRNASLLDRFDLSSVSSVIAGGGPLNKEDYAKMQTVRPNWKLLSGWGQTESCAVGSLAYPKDTVAGSSGVVLPGVRLRMRNDDGNLVQGLEEMGEIEMSSPSVLYEYIDNATEALITPHTEEYWRPTGDVGLIRECPSGIQHLFIVDRIRDMIKVKGHQVAPGEIEVHLMKHDAVGETAVVGIADAVAGERPLAFVIREPSYSPETSDAELRKILQDHNDSALPEIYRLQNRIIIVESIPKSANGKILKRELRKQVVGWTPPKE
What is the function of this protein?
AMP-dependent ligase; part of the gene cluster that mediates the biosynthesis of verlamelin, a lipopeptide that exhibits antifungal activity against plant pathogenic fungi (PubMed:24848421).  Verlamelin is a cyclic hexadepsipeptide and is bridged by ester bonding between a 5-hydroxytetradecanoic acid moiety and a carboxyl group on the terminal Val of amide-bonded tetradecanoyl-hexapeptide D-allo-Thr-D-Ala-L-Pro-L-Gln-D-Tyr-L-Val (PubMed:24848421).  VlmA and vlmB are altogether regarded as essential components in the biosynthesis of 5-hydroxytetradecanoic acid (PubMed:24848421).  VlmA catalyzes the hydroxylation at position C5 of tetradecanoic acid produced in primary metabolism, while the precise function of vlmB still remains to be solved (PubMed:24848421).  To be loaded onto the waiting NRPS, 5-hydroxytetradecanoic acid is activated in the form of acyladenylate by the AMP-dependent ligase vlmC (PubMed:24848421).  VlmS seems to accept the fatty-acyl intermediate onto the initial module to further elongate amino acid residues by the downstream modules (PubMed:24848421).  In addition, in the last module at its C-terminus, vlmS contains a surplus condensation (C) domain that may be involved in cyclization, the last step to form verlamelin (PubMed:24848421).
What are the official names of this protein?
AMP-dependent ligase vlmC, Verlamelin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RR7_MAIZE
Sequence: MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGSGGAIRKKEATHRMAEANRALAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FACR1_XENLA
Sequence: MLSIPEFYQGKNVLITGATGFMGKVLLEKLLRSCPNTKAVYVLVRHKAGQKPRERVAEMMSCKLFDKLRDEQPDCAQKVIAISSELTQPELDMSKEDQDTLIDCIDIVFHCAATVRFNESLRDAMQLNVIATRQLLYLAQKMKKLEVFIHVSTAYANCNRKQIEEVVYPPPVDPKKLIESLEWMDDSLVNDITPKLIGDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRPKNMLVYNCTTGGTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPALLYDVYLRITGRSPRMMKTITRLHRAMMLLEYFTSNSWVWNNENTNMLMSQLSPEDKKVFNFDVRQLHWAEYMENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVVLIWRVFIARSQMARNIWYFVVSMCFKFLSYFRASSTMRY
What is the function of this protein?
Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols.  It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols.  In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
What are the official names of this protein?
Fatty acyl-CoA reductase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: BPT_GRABC
Sequence: MNDSKPLYRPQFFYTTGASPCPYLDGRMERKVVTEITGPDAETLHNRLSRAGFRRSHNIAYAPVCQGCNACVPIRIAVNDFRLTRTRRRINRTNAGVEMFDVPAQATHEQFMLFQRYQKSRHGDGDMAAMGFTDYRAMVEDTPIQTSILEFRDQDDVLLCACLTDRLNDGLSAVYSFYDPDLPQRSLGSYAILSMVAQTKAEGLPYLYLGYWVANSRKMAYKSAYQPAEILSRGAWRPLTQADIEEQEEQTRPLFRPSATGFSTGQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_STRPI
Sequence: MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNTFRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKGGKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFGFILSNYDSLFITIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CK068_HUMAN
Sequence: MAAAAAAAVAGVGRGGGGAEPRQERSRARGWAGVERSEGRRMEPGEELEEEGSPGGREDGFTAEHLAAEAMAADMDPWLVFDARTTPATELDAWLAKYPPSQVTRYGDPGSPNSEPVGWIAVYGQGYSPNSGDVQGLQAAWEALQTSGRPITPGTLRQLAITHHVLSGKWLMHLAPGFKLDHAWAGIARAVVEGQLQVAKVSPRAKEGGRQVICVYTDDFTDRLGVLEADSAIRAAGIKCLLTYKPDVYTYLGIYRANRWHLCPTLYESRFQLGGSARGSRVLDRANNVELT
What are the official names of this protein?
UPF0696 protein C11orf68, Basophilic leukemia-expressed protein Bles03, Protein p5326.
What is the protein family that this protein belongs to?
Belongs to the UPF0696 family.
Protein: EUPF_PHOSX
Sequence: MRYHLSALVLVFTAFRETLTAPTPGNNTIPLPNRLLHQWPNGTWVENISVRPNGNLLVTTSTPDGSVWQVKEPWKENPEVERVFNFDEWVDRLIGIGETQDDKYVVVGSRFYSTDAQSSHVARTFCAMELDFSGNTTEPSARLIAWMPESYLLQGVAALPWDRDTVLISDQYVLRPRAVQIDWTPSPGQIWVLDTRTGEYGLVMTDYAELNTTYAKGPDVGIDGIKIRDHDLFWVNQDDSGIYRVKIDDAGVPVAPVKPQLVASYNTMWDDMAFDPFNENVIWATGLNAVFAATLDGQIVPVDGVGTSDNLTLPGPTACAFGRTEKDKSILYVTGNLLTVPESLLDVKLGGW
What is the function of this protein?
Putative hetero-Diels-Alderase; part of the gene cluster that mediates the biosynthesis of eupenifeldin, a bistropolone meroterpenoid that acts as an antitumor agent (PubMed:30980906).  The first step of eupenifeldin biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase eupA (PubMed:30980906).  Oxidative dearomatization of 3-methylorcinaldehyde likely catalyzed by the FAD-dependent monooxygenase eupB is followed by oxidative ring expansion by the 2-oxoglutarate-dependent dioxygenase eupC to provide the first tropolone metabolite, tropolone stipitaldehyde (Probable).  In parallel, generation of sesquiterpene alpha-humulene from farnesylpyrophosphate (FPP) is catalyzed by the terpene cyclase eupE (PubMed:30980906).  The cytochrome P450 monooxygenase eupD then hydroxylates humulene to humulenol (PubMed:30980906).  The putative Diels-Alderase eupF probably catalyzes the formation of the tropolone-humulene skeleton by linking humulenol and the polyketide moiety (Probable).  The short-chain dehydrogenase/reductase eupG and the flavin-dependent monooxygenase eupH are also essential for eupenifeldin biosynthesis and are likely the additional decorating enzymes of the tropolone-humulene skeleton to produce final eupenifeldin or derivatives (Probable).
What are the official names of this protein?
Putative hetero-Diels-Alderase, Eupenifeldin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the eupF Diels-Alderase family.
Protein: OBG_SHIF8
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK24_GUITH
Sequence: MTIKQGDKVQVIAGSYKGEITEVLKVIRKSNSLILKNINIKNKHVKPKKEGEVGQIKQFEAPIHRSNVMLYDEESQIRSRSKFIISQDGKKVRVLKKLVKN
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PANB_SYNS3
Sequence: MRPAELIRFKQSGRAITMLTAWDALSAALVEEAGADVVLVGDSLAMVVLGHATTLPVTLEHMLHHTQAVCRGMSKPLAQQPLVVCDLPFLSYQCGLDRAVAAAGTILKESDAAAIKLEGGEPEIVAVVDRLVRMGIPVMGHLGLTPQAVHRLGYRRQGIDPRSQDKLHRQAQALQDAGCFSLVVEHVPSELAGRLRRTLSIPVIGIGAGPDCDGQVSVTADLLGLTPSQPPFTPARMQGRELSINALKSWLKEQRDQRATPTTPPPPPAPDC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.