PharMolix/UniProtQA huggingface dataset:
Protein: BH140_ARATH
Sequence: MDDFNLRSENPNSSSTTSSSSSSFHRHKSETGNTKRSRSTSTLSTDPQSVAARDRRHRISDRFKILQSMVPGGAKMDTVSMLDEAISYVKFLKAQIWYHQNMLLFINDHETTSSCTYSPGAGEFGPKLFGYDDDYAPIMDTYSQGVPLTVADSKYTPWFGSVDDEQEHVTYFKYRRATRHALRGHCNCIIGETEEFADQREKMEVQIEESGKNQTSPESIEADKAKQIVVLLIGPPGSGKSTFCDTAMRSSHRPWSRICQDIVNNGKAGTKAQCLKMATDSLREGKSVFIDRCNLDREQRSEFIKLGGPEFEVHAVVLELPAQVCISRSVKRTGHEGNLQGGRAAAVVNKMLQSKELPKVNEGFSRIMFCYSDADVDNAVNMYNKLGPMDTLPSGCFGEKKLDTKSQPGIMKFFKKVSALPASSSNEATNTTRKADEMTANVRVSPVKLGSADIVPTLAFPSISTADFQFDLEKASDIIVEKAEEFLSKLGTARLVLVDLSRGSKILSLVKAKASQKNIDSAKFFTFVGDITKLRSEGGLHCNVIANATNWRLKPGGGGVNAAIFKAAGPDLETATRVRANTLLPGKAVVVPLPSTCPLHNAEGITHVIHVLGPNMNPNRPDNLNNDYTKGCKTLREAYTSLFEGFLSVVQDQSKLPKRSSQTAVSDSGEDIKEDSERNKKYKGSQDKAVTNNLESESLEDTRGSGKKMSKGWNTWALALHSIAMHPERHENVVLEYLDNIVVINDQYPKARKHVLVLARQESLDGLEDVRKENLQLLQEMHNVGLKWVDRFQNEDASLIFRLGYHSVPSMRQLHLHVISQDFNSDSLKNKKHWNSFTTSFFRDSVDVLEEVNSQGKANVASEDLLKGELRCNRCRSAHPNIPKLKSHVRSCHSQFPDHLLQNNRLVARAET
What are the official names of this protein?
Transcription factor bHLH140, Basic helix-loop-helix protein 140, AtbHLH140, bHLH 140, Transcription factor EN 122, bHLH transcription factor bHLH140.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_CHLCV
Sequence: MRSQLSLMGKKEGMIHVFDKDGNLVACSVISVGSNVVTQIKVDSTDGYNAIQMGANEINVPEKTLEKRMNKPELGHLKKSGSRVFGLLKEVRLSEDAINEVSLGNEFGLEVLEDISSVDISGVSKGKGFQGVMKRFGFRGGPKTHGSGFHRHAGSIGMRSTPGRCFPGSKRPSHMGTVNVTVKNLEVVKIDLEKKVLLVKGAIPGPRGSVVVIRRSSRAKG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PFDB_METTP
Sequence: MSGELPPQVQNQLAQLQQLQQQAQALVAQKSQIELLKKEAEAAIKELDKSPDDVVVYKNVGELMLRSDKATLMTELKERVDLLDLRLKTVAKQEERIQSRFNQLQDQLRQSLGQMPPRGG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPO15_SCHPO
Sequence: MSNQSSSGSNTSDLDEESASSLVSSAASPFIDSDLETPRPNISRASTGQLAEDGDTSSQHEDSSEELKRQEVRGMRRHSDLSIDAKLGSSEGSTASSALPLTPRSPSNASWLLVRGGLLDSPILDINSVTQKSNLLNELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQKKLTNMESNFSAKQSEAYDLSRQLLTVTEKLDKKEKDYEKIKEDVSSIKASLAEEQASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINEEDSKLLEELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLLESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLNVAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLEYHKSQVESELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLRSLEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSGKLKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQEQLIPRSSILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVLDSFKQQVAKLQFLAGAEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENLGKSIEALYFALNREISFRKSLALSKSAYHNLLVRDSPKFNPDSQITYSIPVTNTKQSLLRSAILCVISLQRLRLLGQRHSFCEEVIENLSCV
What is the function of this protein?
Has a role in the initiation of spore membrane formation.
What are the official names of this protein?
Sporulation-specific protein 15.
What is the protein family that this protein belongs to?
Belongs to the MPC70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: DDX10_DICDI
Sequence: MNKDKSKQKPQKKENNNNNNKNNNNNNNKTENNKTNKDFTKNKFDKDAKIDKVDNKKIFHNRSSQKRIAKLKKIELQKKPLTLKLNEIKSIEQRLIDEAPQRGTNPLANISSTTATTTTTTATKNDKEKEKEYKIDYPSATDFKDLPISQLTLKALTESKFLKLTDIQRASLPHTLCGRDILGAAKTGSGKTLSFILPILETLWRNRWGRDDGIGAIVLSPTRELAIQIFDVLKAVGKYHTFSAGLIIGGRNVQQEKDKINAMNILIATPGRLLQHMDETYGFDCSNLKILVLDEADRILDLGFSKCLNSIVENLPRERQTLLFSATQTKSIRDLARLSLQEPEYISVYEKDITTTPQNLTQTLCVIPLEMKLNMLFSFIKTHLTSKIIVFFASCKQVRFAHETFKLLNPGTTLFPLHGKMKQWTRLEVFEDFCKKKAGTLFATDIAARGLDFPAVEWVIQVDCPDDIETYIHRVGRTARNDAPGQSITILLPSEKDGMVNLMEKQKMKFEILEPNPEKLVSIDSKLSSFLSEKTDLKYLAQKSFVSYLRSVYRQSNKEIFKIQELNINEFSKSLGLLGTPNIQFGKASADSKNKSFVVSNIQKQLKDKKSKGEKDIDSSDDDDDDEERNKIGNSDDEDSEDDSDFQDDSDDDNKKVTKQQPKTNIEKLFDRKNANVMSETYQKLRTKEEDEEDDSMFVVKRRDHDLDNLDIVKRLSRKENKEKNFINDPTKLKFQESTSVPKDGKLPTSYIEKVKSEVEKGDVQDKILLKERLKRKKLKLQSKELRKQSGGGATGDDEEESVAYFVPPGEKDPYENGENDSDDESNDDDVWGQEYNSDDDDDDEESESEEQPKPITKKRTLEDHEESALKFLKKNRI
What is the function of this protein?
Probable ATP-dependent RNA helicase which may be involved in ribosome biogenesis.
What are the official names of this protein?
Probable ATP-dependent RNA helicase ddx10, DEAD box protein 10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EF2_PYRHO
Sequence: MGRREEMIAKIKELMLQPERIRNIGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFDEQEQARGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAVEGVMPQTETVVRQALREYVKPVLFINKVDRLIRELKLTPQQMMERFSKIIMDVNRLIQRYAPEEYKKKWMVKVEDGSVAFGSAYYNWALSVPFMKRTGVKFNEIIDLTLKGDNRTLRQKAPLHVVVLDMVVRHLPSPIEAQKYRIPHLWEGDISSDIGQAMLNCDPKGKMVMVVTKIIIDKHAGEVATGRVWSGTVKSGQEVYLINTKRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETVAEEQIEPFEALHYVSEPVVTVAIEAKNVKDLPRLIEALRQLAKEDPTLHVKIDEETGQHLLSGMGELHLEVKLYKLKKDWGIDIEVSEPIVVYRESITKSSPMVEGKSPNRHNRFYIVVEPMPDEIYNAIKEGIIPEGRVKNPKEVAKKLAELGMDYEIARGIVDIYNGNMFIDNTKGVQYLNEVMDLLIDGFHQAMDEGPLAREPVMKVIVRLLDAQVHEDNVHRGPAQIYPAIRTAIHCAMMKSNPVLYEPYQKVIINIPYEYMGAVSREITQRRGQLVDMKQEGEVMTIIAEAPVAEMFGFAGSIRSATSGRALWSTEHAGFKRVPNELAQQIIRQIRQRKGLDPNPPTEKDVCPLF
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_PORPU
Sequence: MYQNNLIDFNPYSCLSAVEVGKHLYWKIGSLQLHGQVFIVSWLVIAALLTISFLGTRNLQRIPEKFQNFMEFILEFLQDIAKNQIGEHEYRPWVPYIATLFLFILGCNWAGALIPWKLIHLPEGELAAPTNDINTTVALSLLTSLAYFYAGLSKKGLGYFARYVQPTPVLLPINILEDFTKPLSLSFRLFGNVLADELVVSVFTLLIPILIPLPVMILGLFASSIQALIFSTLSAAYIGEAMEGHGEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MSTN1_BOVIN
Sequence: MSQAGAQEAPIKKKRPPVKEEDLKGARGNLTKNQEIKSKTYQVMRECEQAGSTAPSVFSRARTGAETVFEKPKAGPAKSVFG
What is the function of this protein?
May be involved in the development and regeneration of the musculoskeletal system.
What are the official names of this protein?
Musculoskeletal embryonic nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the MUSTANG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NS2A_CVBEN
Sequence: MAVAYADKPNHFINFPLTQFQGFVLNYKGLQFQLLDEGVDCKIQTAPHISLAMLDIQPEDYRSVDVAIQEVIDDMHWGEGFQIKFENPHILGRCIVLDVKGVEELHDDLVNYIRDKGCVADQSRKWIGHCTIAQLTDAALSIKENVDFINNMQFNYKITINPSSPARLEIVKLGAERKDGFYETIASHWMGIRFEYNPPTDKLAMIMGYCCLEVVRKELEEGDLPENDDDAWFKLSYHYENNSWFFRHVYRKSSYFRKSCQNLDCNCLGFYESSVEED
What are the official names of this protein?
Non-structural protein 2a, ns2a, 32 kDa accessory protein, 32 kDa non-structural protein, ns2.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns2a protein family.
Protein: FERON_ARATH
Sequence: MKITEGRFRLSLLLLLLLISAATLISAADYSPTEKILLNCGGGASNLTDTDNRIWISDVKSKFLSSSSEDSKTSPALTQDPSVPEVPYMTARVFRSPFTYTFPVASGRKFVRLYFYPNSYDGLNATNSLFSVSFGPYTLLKNFSASQTAEALTYAFIIKEFVVNVEGGTLNMTFTPESAPSNAYAFVNGIEVTSMPDMYSSTDGTLTMVGSSGSVTIDNSTALENVYRLNVGGNDISPSADTGLYRSWYDDQPYIFGAGLGIPETADPNMTIKYPTGTPTYVAPVDVYSTARSMGPTAQINLNYNLTWIFSIDSGFTYLVRLHFCEVSSNITKINQRVFTIYLNNQTAEPEADVIAWTSSNGVPFHKDYVVNPPEGNGQQDLWLALHPNPVNKPEYYDSLLNGVEIFKMNTSDGNLAGTNPIPGPQVTADPSKVLRPTTRKSKSNTAIIAGAASGAVVLALIIGFCVFGAYRRRKRGDYQPASDATSGWLPLSLYGNSHSAGSAKTNTTGSYASSLPSNLCRHFSFAEIKAATKNFDESRVLGVGGFGKVYRGEIDGGTTKVAIKRGNPMSEQGVHEFQTEIEMLSKLRHRHLVSLIGYCEENCEMILVYDYMAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYLHTGAKHTIIHRDVKTTNILLDEKWVAKVSDFGLSKTGPTLDHTHVSTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEALCARPALNPTLAKEQVSLAEWAPYCYKKGMLDQIVDPYLKGKITPECFKKFAETAMKCVLDQGIERPSMGDVLWNLEFALQLQESAEENGKGVCGDMDMDEIKYDDGNCKGKNDKSSDVYEGNVTDSRSSGIDMSIGGRSLASEDSDGLTPSAVFSQIMNPKGR
What is the function of this protein?
Receptor-like protein kinase that mediates the female control of male gamete delivery during fertilization, including growth cessation of compatible pollen tubes ensuring a reproductive isolation barriers, by regulating MLO7 subcellular polarization upon pollen tube perception in the female gametophyte synergids.  Required for cell elongation during vegetative growth, mostly in a brassinosteroids- (BR-) independent manner.  Acts as an upstream regulator for the Rac/Rop-signaling pathway that controls ROS-mediated root hair development.  Seems to regulate a cross-talk between brassinosteroids and ethylene signaling pathways during hypocotyl elongation.  Negative regulator of brassinosteroid response in light-grown hypocotyls, but required for brassinosteroid response in etiolated seedlings.  Mediates sensitivity to powdery mildew (e. g.  Golovinomyces orontii).  Positive regulator of auxin-promoted growth that represses the abscisic acid (ABA) signaling via the activation of ABI2 phosphatase.  Required for RALF1-mediated extracellular alkalinization in a signaling pathway preventing cell expansion.
What are the official names of this protein?
Receptor-like protein kinase FERONIA, Protein SIRENE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Accumulates asymmetrically in the female gametophyte synergid membrane at the filiform apparatus.
Protein: SYFB_PSESM
Sequence: MKFSEQWLRGWVSPQVSRDELVARLSMAGLEVDSVTLAAGIFTGVVVGEVLSTEQHPDADKLRVCQVSNGRETFQVVCGAPNVRPGLKIPFAMIGSELPGDFKIKKAKLRGVESNGMLCSAAELQAGEGNDGLMELAADAPVGQDIRVYLGLDDASIEVDLTPNRGDCLSVAGLAREVGALYAADVTRPQIAAVSAVHDEVRPVEVLAPAACPRYLGRVIRNVDLSRPTPLWMVERLRRSDVRSIDAAVDITNYVMLELGQPLHAFDLAEINGGIRVRMAEEGEKLVLLDGQEVSLRADTLVIADHQRALAIAGVMGGEHSGVTAGTRDIFLESAFFDTISVAGKARSYGLHTDASHRYERGVDWQLAREAMERATGLLLDITGGEAGPVIEVVSEQHLPSIAPVTLRASRVEQMLGLVIENAEIERLLTGLGLTVSAEADGQWRVDVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPQANAEAKGDLPELRRLLVARGYQEAITYSFIDPKWFELFSPGVKPLLLANPISNDMAAMRASLWPGLVKALQHNLNRQQDRVRMFESGLRFVGQLDGLKQEPMLAGVVCGSRLPEGWAQGRDAVDFFDVKADVEAVLGFAGALGEFTFTPGQHPALHPGQTARILRDGREVGFLGAIHPELSKNLGLDRPVFVFELVLAEVATGRLPKFHELSRFPEVRRDLALLADRDVSASAVLDVIRENAGEWLTDLRLFDVYQGKGIDPHRKSLAVGLTWQHPSRTLNDDEVNATTLAILTSLEERLNATLRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYNB_MYTGA
Sequence: MKATMLLAVVVAVFVAGTEAHPHVCTSYYCSKFCGTAGCTRYGCRNLHRGKLCFCLHCSRVKFPFGATQDAKSMNELEYTPIMKSMENLDNGMDML
What is the function of this protein?
Bacteriolytic activity against Gram-positive bacteria M. luteus, B. megaterium and A. viridans and Gram-negative bacteria E. coli D31.  Possesses antifungal activity against F. oxysporum.
What are the official names of this protein?
Myticin-B.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_NITSB
Sequence: MKVYLCAISNISSGVCAEDCKFCTQSTKYRADIPRYKYKSIETIVEEAKKAKAAKAIGFCLVTAGKGIDDKILDFVTQAARAVKKEVPDISLIGCNGTAEVWQLKELKHAGIDNYNHNLETAKSFYEQICSTHSWEERYQTCLNAKEAGLNLCTGGIFGLGESKEQREEMMDQIASLEPMSVPINFYHPNEALPLPQTTIDPSDALSIIQDMRKRVPNAMIMVAGGRELVFGEQWPKILDAGANAIVIGDYLTTKGERPDKDIQTLQKLGVEIATSCHE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ILVD_PHOLL
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPAIFVSGGPMEAGKTKLSDQIIKLDLIDAMIQGANPKVSDEDSNQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKALFLNAGKRIVELTKRYYEQNDDSALPRSIATKAAFENAMMLDIAMGGSTNTVLHLLAAAQEGEVDFTMADIDRLSRQIPHLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRQVKNVLGLDLLQTLNQYDVMQTVDESVKEMYSAGPAGIRTTQAFSQDCRWPSLDTDRVEGCIRDIEHAYSRDGGLAVLFGNLAIDGCIVKTAGVDEGSLTFRGPAKVYESQEDAVDAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSVGLGKSCALITDGRFSGGTSGLSIGHVSPEAANGGLIGLVQDGDIIDIDIPLRKIRLDVDERILATRKEVEFARGDKSWTPKARERQVSLALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PSD_ECOSE
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBIE_PSEPW
Sequence: MNDQRKGEHAEPTTHFGYQDVPESQKAKKVAEVFHSVAAKYDLMNDVLSGGMHRLWKRFTIELSGVRSGNRVLDIAGGTGDLAAKFSRLVGPTGQVVLADINDSMLKVGRDRLLDRGVAGNIEFVQADAEKLPFPDNHFDCVTIAFGLRNVTHKDEAIRSMLRVLKPGGRLLILEFSKPTNKLMSKAYDAYSFAFMPLAGKLITNDSESYRYLAESIRMHPDQETLKAMMVDAGFDRVTYHNMTSGIVAVHRGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RHG20_MOUSE
Sequence: MEAMSPQQDALGAQPGRSSSLTGMSRIAGGPGTKKKMKTLAERRRSAPSLILDKALQKRPSTRDSHSASIDTCAFLSSFMCSSRTLLIDGPVELKRGLQRQERHLFLFNDLFVSAKIKYNNNFKIKNKIRLTDMWTASCVEEVGEGNMNAQKSFVLGWPTVNFVATFSSPEQKDKWLSLLQRYIALEKEKDYPKSIPLKIFAKDIGNCAYFKTITVMNSDTASEVINMSLQMLGITGSERDYQLWVNSGKEAAPYPLIGHEYPYGIKMSHLRDTALLTQGSRDSASPSQLQEPFLMEQLPREMQCQFILKPTRLATAQQLSDSSQKTFKRRRSIINWAFWRGSSTHLDNLPMSPTSPMPGQLFGVSLPDLCENDNLPKPILDMLSFLNQKGPLTKGIFRQSANMKSCRELKEKLNSGIEVHLDCESIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINIIQRLLDQLPRANVVFLRYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSILWPPASSSPELENEFTKKVSLLIQFLIENCCRVFGEEIASLLGELSERSDREHTPDITCFQMNDSSYDSLENELNEEADAPCSDLVKKLGQGSRSMDSVLTLSDYDLEQPEVEGLLTLSNFDLDQSKEEHIPIKPPLEPKPVNVFVGYRKVSLGEHARAPAGPGTLSCLPVAAADAPKVLRRHRRSSEPSIDYLDTKLSYLREFYQKKLRKSSCDAVLSRKDEDYLKQTQPQKKGDKVCLKQSSVTGTDVSKRNTANENIKKKSLSGHEGTQVTLFTKSKPVPISVASYSHGSSQDHPRKQAFDADPCRFSPPHLTDAQKSSRVQHRRCSEPSIDDQNYKLSYLRGIYSMKQNKASCEAGLLHGEDDYLRRHKSLQIEGQKLINQSLVMGIEVGKSSSSHQSTEKVLPPRLNLCPRASYSSLSSPGSSPSGSSVSSQDSAFSQISEHSVFTPTETSSPIDCTFQTQRKQEELSSDFDSPSRLSGMPGPSMGQASSHLAYLRKGTTEQPSQMHSVTLHPSAWLRSGLVTLKNWSLKKKTKAARPEDRKVCSLKEPLELPSCASGTPEADSLQESQDDLQGDEGPGQTACGFSSYACQDSEQHAGSPFHLAESRLKPCMKLYKGEESGGQYPCDNPWEGASSSLETTEDTANPGAEPTTFAMTGTDI
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 20, RA and RhoGAP domain-containing protein, RARhoGAP, Rho-type GTPase-activating protein 20.
Protein: ZNUC_VIBVU
Sequence: MSALISLKALSVTFDDKKVLDSISLDLHKGKITTLIGPNGAGKSTLVKIIIGLLKPTSGQVQRQAKLTIGYVPQKLKLNDTLPLNVIRFLNLSGKYSQQETMEALRLVGAEHLYKSNMHKLSGGETQRVLLARALLQRPDLLVLDEPAQGVDIQGQIDLYDLIESIRHRFDCAVFMVSHDLHLVMAKTDEVICLQHHVCCSGAPEDITQHPSYIALFGSAARDSLAIYHHQHDHHHHDLAGQPVSGDATQCNHHHHGHHHD
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: M1_I80AC
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: MNMG_ACIF2
Sequence: MQNSFDVIVVGGGHAGTEAAAAAARLGVRTLLLTQNLDTIGQMSCNPAIGGIGKGHLVKEVDALGGIMALAIDQAGIQFRTLNASKGPAVRATRAQADRSLYKRAVRRLLEDIPALQLFQGMVGDLLMEGDRLGGVILETGLVLRAAQVVLTTGTFLGGRVHMGDQNYPAGRAGDPPSNALAQRLREMAFPVARLKTGTPPRIDGRSIDYGVLEAQPGDAPPPAFSFMTRRIGVPQLACHITHTNARTHEIIQTNLHQSAMYGGHIQSVGPRYCPSIEDKVVRFADKASHQVFLEPEGLDTHEVYPNGISTSLPFGVQIELVRSMRGLENAVLLRPGYAIEYDYLDPRELHPSLESRRLPGLFCAGQINGTTGYEEAAAQGLLAGLNAARRARELAAWTPGRHEAYLGVMVDDLVTRGLDEPYRMFTSRAEYRLQLREDNADLRLTPHGRALGLVDDQRWTAFSAKQDAVQAERNRLEGLRIHPGSAIAGRIAAKTDQPLSRDVTALELLRRPDWDYASLLQVLDLVPCSDAQACEQLEIECKYAGYVARQHDEITRAARWEGTDIPADMDYAAVRGLSTEVMQRLARQRPQTIGLASRIPGVTPAAVSLLLIHVKRRGLRQAG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA2_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN
What is the function of this protein?
Basic protein that binds to cell membrane and depolarizes cardiomyocytes.  It also shows lytic activities, but 2-fold less important than that of CTX-A4.  It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity.  It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes.  It may also target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
What are the official names of this protein?
Cytotoxin 2, Cardiotoxin 1A, Cardiotoxin 2, CTX-2, Cardiotoxin A2, CTX A2, Cardiotoxin II, Cardiotoxin analog II.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.