PharMolix/UniProtQA huggingface dataset:
Protein: EIF3I_CANGA
Sequence: MRPIVLMGHERPLTQVKYNREGDLLFTCSKDISASVWYSNNGERLGTLDGHMGSIWSIDSDHTSLYCVTGSADYTIKVWTLMNGQCVQTWNCPVPVKRVEFSPCGKYILAILDNVMKKPGSIEIYEVKRNPETNEITEFVEEPIHSIVTHEGLDAASVAGWSGEGKYIIAGHKDGKISKYDTQDGYKLVESQQVHKDSVSDLQFSPDRTYFITCSRDSNAHIIDIETFKVLKTYETDSPLNSAAITPLKEFVILGGGQDASEVTTTSASEGKFEARIYHKVFEEEIGRVVGHFGPLNSIAVSPQGTSYTSGGEEGLVRLHHFEKSYFDFKYDVEKAADAKEHISHEA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_HYDCU
Sequence: MATINQLVRKPRKDKMKKSNVPALEACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTNGYEVSSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGSLDCAGVDGRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: COAD_BDEBA
Sequence: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPC_CHRVO
Sequence: MRVENHSPSLSKLNPPEAGSGDPTAIGRRLSGIRRAPLPHVSAGSDGEAAAAGKIGAFLRKAVAAQSYGLMFANGKLFEATGDALEKRGQYGFSALQRLDGLSRRNLAAVEARLGALDSAERGLKERIMTGAWHFRHQSNAALDDGKTAAIASNHLLARESRSSGGNTFAGDKALLSNHDFVFFGVEFSGRGKQDKPLNHKHSTMDFGANAYVVPDTLPACRHGYLTLTDHFFNRVPGGREAEHQDFVGSFPQMGAETGRWIHEGKYRQNAPIFNYRDMKAAVALHLIEFLRDSKDAAFKAYVFDQAMQSGQALDRVLNSVFQAEFHIPRLMATTDYAKHPLRPMLLKEAVDSVNLPALSGLVSSKGDAVTAMWHAIDKGKDAVAAHLLGNWRFEAGDFASAPPGFYHELNYALSEHGASVYILDQFLSRGWAAVNAPFEHVNSGETMLDNAVKYGNREMAAALIKHGADRNLLSEWNGGKLDALLA
What is the function of this protein?
ADP-riboxanase effector that inhibits host cell programmed cell death (PubMed:34671164, PubMed:35338844, PubMed:35446120, PubMed:36423631).  Acts by mediating arginine ADP-riboxanation of host caspases (CASP3, CASP7, CASP8 and CASP9), blocking their processing and activation (PubMed:35338844, PubMed:35446120, PubMed:36423631).  ADP-riboxanation of host apoptotic caspases (CASP3, CASP7, CASP8 and CASP9) prevents their activation, thereby inhibiting host cell apoptosis (PubMed:35338844, PubMed:35446120, PubMed:36423631).  ADP-riboxanation of host CASP8 also inhibits host cell necroptosis (PubMed:35338844, PubMed:35446120).  ADP-riboxanation of host CASP3 also abolishes pyroptosis by preventing its ability to cleave GSDME (PubMed:35338844).  May also able to inactivate CASP4/CASP11, blocking inhibiting LPS-induced pyroptosis; however this activity is unsure in vivo (PubMed:34671164).  ADP-riboxanation takes place in several steps: CopC first binds host caspases and NAD(+); NAD(+) is hydrolyzed to nicotinamide and ADP-D-ribose (PubMed:36423631).  CopC then transfers the ADP-D-ribose to the modified arginine of caspases and forms the ADP-D-ribose-deacylization on arginine, leading to deamination to remove one N-omega group on target arginine (PubMed:35338844, PubMed:36423631).
What are the official names of this protein?
Arginine ADP-riboxanase CopC.
What is the protein family that this protein belongs to?
Belongs to the OspC family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS).
Protein: SYFA_THEVO
Sequence: MSEISKNEALILKYLASKNQEIEESNIEIKGLSRQDIASATSWLQVKGLIDVKTREEVAYVLTDEGKRYAENGLPELRAYSILKRKGKLSLRDLQEAMPDEYKIVLAQLAKFGITPKNGVLEYSDGHIEAEISRRQRFLSDLNTDDQEMIEHFKRRKNVIEEKKRSVRIVSINSKGLEQLNNFDQFEAIGEIDSGIITSQAWKTAPFRKYDLDAPVSPTKSYAKHPLVYFINEIRRIFLDMGFTEMSGHYIESALWDMDALFIPQDHPARDMQDTFYVKDSNFTIEHPEIEKRIKRIHERGFDGYSGWGYRWSSDDGKKLILRTHTTVTTARYLYEHNTYPQAIFSVEKVFRHESVDWKHLAEFYQIEGAVYDKNVSVATLKWILRTFYGKLGFEKIRLVPSYYPYTEPSLDVVVEVDGKEMELGGSGIFRPEVGKILGLKAPVMAWGMGLERLAMLYYGLTDVRDLYNTDFSFLEGYKIKY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_YERPN
Sequence: MKAQELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLLKQVRRNVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CIAO1_ASHGO
Sequence: MPNLHLVRSLKLHGDRCWSVDISKGLLATGSADRKIKLVDVRNFKLVEELDDTAHKKAVRSVAWRPHCNVLAAGSFDTTVSIWGRDDDDYSGETELLAVIEGHENEVKSVAWSHDGAYLATCSRDKSVWIWEADELSEEFECNSVLQEHSQDVKHIVWHASRLLLASSSYDDTVRIWAEQDDDWECAAVLSGHGGTVWCSDFERAETGIRLCSGSDDTTVRIWRCLTDDADVFDKEWIQETVLPAVHTRAVYSVSWSADGLIASVGSDGVLAVYKEVQAGRWEVVARVDCAHTVYEINVVKWLALDGRVLLVTGGDDGCVNVWELREE
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: RL35_DECAR
Sequence: MPKMKTKSSAKKRFSIRAGGSIKRGQAFKRHILTKKTTKVKRHLRGATAVHERDAASVRAMMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NCAP_I73A4
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYVQMCTELKLNDHEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWMRELILHDKEEIRRIWRQANNGEDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVREGRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEKEGYSLVGIDPFKLLQNSQIFSLIRPKENPAHKSQLVWMACHSAAFEDLRVSNFIRGTKVIPRGQLATRGVQIASNENMETIDSSTLELRSRYWAIRTRSGGNTSQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMENARSEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFDS
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YCGL_ESCF3
Sequence: MLCVIYRSSKRDQTYLYVEKKDDFSRVPEELMQGFGKPQLAMILPLDGRKKLVNADIEKVKKALTEQGYYLQLPPPPEDLLKQHLSLTGHIRTESEQ
What are the official names of this protein?
Protein YcgL.
Protein: KRE28_KLULA
Sequence: MTHYHSEYYSEVEKFEYQVTHVTEQILQEQDRLRGSTLHEYNQTILQLVSDYEMFNSNGQCDPSEINLPLEKLESWTNSLKQIHLELESIDNFLRYAIPSDQTILNLSKFNESKYETLQAEVSELRDINVVQLQKEIESLQQQITTKSDENLLISEKIKESCLEASQDIDQCWKLLEQLEAYENANPSTEVITTTDPAFSTYNQWKWNQLAESELKHINQQLITLRATKEKLDKVFSKRSELETSPKSIETFTSYQLLSQLWRSKFIRQLLPDIANLEVYPQSGKLKFEVGIMQVIMQIESGIIKSVSLFSYELSYDRIETIKEDILGRIEHQKSLFKVLVVITDYIVNSL
What is the function of this protein?
Required for kinetochore binding by a discrete subset of kMAPs and motors.  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: RLME_BURP6
Sequence: MAKNRFNQSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYARNKLAQGKRRDAVREGGIDGTIIALDMLPMEPVADVHFIQGDFREESVLHQLEEVLAGRAVDLVISDMAPNLSGVAVADAARIEHVCDLALEFAQNHLKPDGALLVKCFHGSGYSQIVEKFKHQFKTVAPRKPKASRDKSSETFILGRHLKQPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_STRS2
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFELRFQAAAGQLEQTARLNEVKKQIARIKTVQSETK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PEP2_CROSI
Sequence: VPPHIY
What are the official names of this protein?
Peptide 2.
Protein: SSPK_HALH5
Sequence: MRNKAHGFPHRISFDGEPDRAKHASKRANGTINTKPQERMHQANPDQ
What are the official names of this protein?
Small, acid-soluble spore protein K, SASP K.
What is the protein family that this protein belongs to?
Belongs to the SspK family.
Protein: ATG16_GIBZE
Sequence: MPNWRDQYLSGIKDAELNNPVNMELVQTCSQMADRISALEAEKNGLETLVTTNGKTTARPTEPSTNDPAVAQLKQDLAEALRSKGVAEKRLRSSEEELLQLRSKHKTNTRSIRDLTADKNSLTTRLKDREYELREKRKFIEQVQDEMIALNLQMSMAEKERDKVKKENKELVDRWMKRMAQEAEAMNLANEPIFKKGR
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate (By similarity).  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS) (By similarity).  Recruits also ATG3 to the PAS (By similarity).  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Autophagy-related protein 16.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: DAPE_SALPB
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PAX_I59A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYRENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQEPCVGLPIKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: MRAY_CAUVN
Sequence: MLYLLYEWLARSQEHLPALNLLKYLTFRSGMAMLTAYIVAVAMGSRFIRWMKAKQGKGQPIRTDGIARHVTEKAGTPTMGGFMILAGLFVAALLWADLRNVHVWVVLLITGSYGLLGFMDDYAKVTKQTTAGLSSVQKLVAQFIVAIIATVILILFAPKSPMTPGMETSLVFPIFKALVINLGWFYVAFAAFTIAGFSNAVNLTDGLDGLAIVPVMFAASTFGLIAYLVGNYKFADYLNLHFAPGVGELAVLCGAIIGGGMGFLWYNAPPAKIFMGDTGSLALGGALGAIAVCAKHELVLGIVGGLFVAEALSVMIQVAYFKKTGKRVFLMAPIHHHFEKLGWPESTVVIRFWIVSMILAFIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HMGB4_HUMAN
Sequence: MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKYEALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRGKRVRQS
What are the official names of this protein?
High mobility group protein B4.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Interacts specifically with the sex chromosomes.
Protein: HMG2_DROME
Sequence: MEHFHQIQQTIQHYQQQLAAQQQQQVQQQQLQQHQVVVQQNQQQAHQNSSNTTAGVGTQQLFTYKMASSFPNPATTMAQVVATSNAAGTTGYDYRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQLEEQHDDDDGDGDDDENQ
What is the function of this protein?
Binds preferentially single-stranded DNA and unwinds double-stranded DNA.
What are the official names of this protein?
High mobility group protein DSP1, Protein dorsal switch 1.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RNG2B_XENLA
Sequence: MATPVTAQCSSKTWELSLYELHRTPQAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQDRVLAKLSRLHNQQALSSSIEEGLKMQAMHRAQRVRKHQHESDNTTFSGGEDNCDSRSHVSNPSVHSNQEAGPSRKRSRASEDSGAEPDLSHEGGVRSPDPPGGGENGSEIELVFRAHPLLVEKDGYSQTRYVKTTANATVDHLSKYLALRIALEEEALRGGAEGVTVGEVSEKQYTIYICTGAAGGQYTTLNGSLTLELVNEKYWKISKPLELYYAPTKEQK
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation.  H2AK119Ub gives a specific tag for epigenetic transcriptional repression.  Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.
What are the official names of this protein?
E3 ubiquitin-protein ligase RING2-B, RING finger protein 1B-B, RING1b-B, RING finger protein 2-B, RING-type E3 ubiquitin transferase RING2-B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome.
Protein: ADTRP_RAT
Sequence: MTKTTTCLYHFVVLNWYIFLNYYIPQIGKDEEKLKEFHDGGRSKYLTLLNLLLQAVFFGVACLDDVLKRVIGRKDIKFITYFRDLLFTTLAFPLSTFVFLVFWSLFHYDRSLVYPKGLDDFFPAWVNHAMHTSIFPFSLAETVLRPHNYPSKKLGLSLLGACNFAYIIRILWRYVQTGNWVYPVFASLSPLGIILFFSASYILSASLYLFGEKINHWKWGATVKPRMKKN
What is the function of this protein?
Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (By similarity).  Shows a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (By similarity).  Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) (By similarity).
What are the official names of this protein?
Androgen-dependent TFPI-regulating protein, Fatty acid esters of hydroxy fatty acids hydrolase ADTRP, FAHFA hydrolase ADTRP, Liver regeneration-related protein LRRG140.
What is the protein family that this protein belongs to?
Belongs to the AIG1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalized with TFPI and CAV1 in lipid rafts.
Protein: XERC_HAEI8
Sequence: MLTALNRYWDYLRIERQMSPHTITNYQHQLDATIKILAQQDIHSWTQVTPSVVRFILAESKKQGLKEKSLALRLSALRRFLSFLVQQGELKVNPATGISAPKQGWHLPKNMDGEQIQQLLANDSKEPIDIRDRAILELMYSSGLRLSELQGLDLNSINTRVREVRVIGKGNKERVVPFGRYASHAIQEWLKVRALFNPKDEALFVSQLGNRISHRAIQKRLETWGIRQGLNSHLNPHKLRHSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDQAHPRAKRKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_XANC5
Sequence: MSTTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTEHLMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTPDSSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQRLADISVD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FOLD_CUPTR
Sequence: MPAQLIDGNALAKQIRSEAAQRAARLTERGHQPGLAVVLVGEDPASQVYVRNKVKACEDNGFHSSLDRYPADLSEADLLARIDELNRDPRIHGILVQLPLPKHIDSHKVLEAIAPEKDVDGFHVANAGALMTGAPLFRPCTPYGCMKMLESIQYPLRGARAVVVGASNIVGKPMAMLLLQGGATVTICNSKTRDIGAHTRDADVVVAAVGKRNLITADMVKPGAVVIDVGMNRDDHGKLCGDVDFAGVREVAGYITPVPGGVGPMTITMLLINTLEAAERAAG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MURE_ALKMQ
Sequence: MKLMDLLEEIDTIEIKGEERINIENIYYDSRKVTPNSLFICIEGFQTDGHHFIDQAIKKGAIAIVAQKDMTGLDGVTWVQVKDTRQVMAQLGSTFYGRPSQHLELIGVTGTNGKTSTTYMIKKILENHERKVGLIGTIANWIGNTEVEAQRTTPESIDLQQIFKEMADEKVTECVMEVSSHALALERVAESEFKVGVFTNLTPEHLDFHENIDNYREAKKKLFYLTTVANVINIDDPHGAMIAEEVKKLKPSLITFGIKKQATVMAKNIATTLKDVTFDLVTPVGEARVTVKIPGIFSAYNALASIATSIAIGVPFDVIVQGIQSIPGVPGRFESVLGIKDFSVIVDYAHTPDAIENVIQAAKNVTEHRVITVFGCGGDRDRTKRSVMGEISGSLSDLSVITSDNPRTEDPYKILMMIEAGIKKTKGLYTIIEDRREAIRYAMKEAKKGDIVLIAGKGHEATQQIGSNVIIFDDCGVAREIAKEEGLDDSDIHS
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLIZ_ASPFU
Sequence: MATAMQDVSPSFTSSPTSTMTTISTTTAATAAAAPKPDKPRKLRSACDACHRSKTRCSGGNPCTRCHEYMSPCTYSYSSRCGKPKGARSRKTLEREQRVAAAAESARIAGNPSALASLPATSTCTSTATTAAAAAAATTTTTIATTTAPSQGPAVDSAAAAAAATTSTVASPRADDCLGLFDDDEESNPFFSSGSENTGGTSFSPDWIPPLPSISDSDLSFPLLESCLGPDHDCNDSLFWSTTAEPDCQPTSKEPLDPRSKLLRSCKCLQTLSSLTARDIRRFDATFVFVRNYARAFSAFYHCSHCPKDAGSISMAVTALQLATTALEKTATAGTDAAGFKSGCSGMTAADLDEDLLTPGAEFFLPANGRGASNPAFQLGSYQIAPLPGEPDLEEHSEILNILIRSAVRRLLAVCWQIWDLLRGPASRDGRGHVFEPYDPSSSSSSSSSSFSSGPEIHQLCDLSCSAEAAQFRSTLVQIPARLCNLLAL
What is the function of this protein?
Transcription factor that regulates gliotoxin production and contributes to virulence (PubMed:15979823, PubMed:17030582, PubMed:20548963, PubMed:21612254).
What are the official names of this protein?
C6 finger domain transcription factor gliZ, Gliotoxin production protein Z.
What are the subcellular locations of this protein?
Nucleus.
Protein: YH66_SCHPO
Sequence: MQIGAATEGVEADLSVNAEPDVKPIAKMLSACVGSVITTLTVTPLDVVKTRLQSESISQYSSTQPISSAKILGKGRPAPKPLGGPVSGLYQIARHEGVRSLWRGLVPSLTMLLPANTVQFLGYEQLLPLYSDWGFPAAAAIAGASARTISATIVSPIELFRTRVQAVGGHYPPGHAREIANEVFDGLKLMIHQKGILNLWSGVSVTLWRDVPFSAFYWWSYERIRLFLLGHPSLQAFSSSQSTKDLYINFVSGGISGTLATLLTQPFDVSKTAKQVHGHTLTRGQFMLTLWKRGGPKALWKGTLPRCVKVAPSCAIMISSYHLTKKYFSESVDAY
What are the official names of this protein?
Uncharacterized mitochondrial carrier P23A10.06.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.