PharMolix/UniProtQA huggingface dataset:
Protein: IF1C_ARATH
Sequence: MLQLCSTFRPQLLLPCQFRFTNGVLIPQINYVASNSVVNIRPMIRCQRASGGRGGANRSKPAKPQVKEGSNKTVIEGLVTESLPNGMFRVDLENGDNILGYICGKIRKNFIRILPGDKVKVEMSVYDSTKGRIIFRMSSRD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
Protein: RL21_COXBN
Sequence: MYAIIKTGGKQYRVTEGQMLKVEKLAQDVGQSVKFDDVLMVAAGDELHIGTPSVKDAAVTAEVVDQGRQAKIEIIKFKRRKHHMKRQGHRQDFTAVKVTEIALGKAKKEVKTDGA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CAST2_XENTR
Sequence: MELHILEHRLKVASIAKENIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSSSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILQVVNGETVAADNLGVTNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPYTLPTVTTLLMDVMFYSNGVKDSVVGSEEPGHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVINALQVSQAEKH
What is the function of this protein?
Functions as a negative regulator of the TORC1 signaling pathway.
What are the official names of this protein?
Cytosolic arginine sensor for mTORC1 subunit 2, GATS-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the GATS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TPR1_ORYSJ
Sequence: MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTPPNGARASPVSVPLAAVPKAGGTYPPLTAHTPFQPPPAGPSLAGWMANAAAATSSVPSAVVAASSLPVPPNQAVPIMKRPTITDYQSAESEQLMKRLRPSGHGVDEATYPAPIPQPLWSVEDLPRTVACTLSQGSSVTSMDFHPTRHTLLLVGSTNGEITLWEVGMRERLFSKPFKIWDIQACSPQFQSVAKESSISINRVTWSPDGDLIGVAFAKHLIHLHAYQQPNETRQVLEIDAHSGAVNDIAFSRPNKQLCVVTCGDDRLIKVWDMHGQKLFSFEGHEAPVYSICPHHKESIQFIFSTSLDGKIKAWLYDHMGSRVDYDAPGKWCTTMLYSADGTRLFSCGTSKDGDSYLVEWNESEGSIKRTYSGFRKKSAGVGVVQFDTAQNHILAAGEDNQIKFWDVDNTTMLSSTEADGGLPGLPRLRFNKEGNLLAVTTVDNGFKILANADGLRTLRAFGNRPFEAFRSQYEASSMKVSGAPVVAGISPNIGRMDHIDRNSPAKPSPIMNGGDPASRSIDIKPRISEERPDKAKPWELMEVLNAQQCRVATMPETPDQASKVVRLLYTNSGVGLLALGSNAIQRLWKWARNDQNPSGKATANVVPQHWQPNSGLVMQNDTADTNPEDAVPCIALSKNDSYVMSACGGKVSLFNMMTFKVMTTFMPPPPASTFLAFHPQDNNIIAIGMEDSTIHIYNVRVDEVKTRLKGHQRRITGLAFSNNLQILVSSGADAQLCVWATDTWEKKKSVAIQMPAGKTPSGDTWVQFNSDWSRLLVVHETQLAIYDASKMERIYQWIPQDALSAPISHASYSRNSQLVFAAFTDGNIGIFDVENLRLRCRIAPPAYLSSAAINSNPSVYPLVVAAHPQESNQFAVGLSDGSVKVIEPLESEGKWGTTPPTENGVPNGRTSTSSATSNPAADQIQR
What is the function of this protein?
Probable downstream regulator of strigolactones signaling.
What are the official names of this protein?
Protein TPR1, Aberrant spikelet and panicle1-related 2, Protein ASP1-RELATED 2, OsASPR2, Topless-related protein 1, Topless-related protein 2, OsTPR2.
Protein: CE152_XENLA
Sequence: MSIDFDSGALQTQQEDEEYDKEDYAREQELQQLLTDLPHDMLDDSLSSSPEPSYSDCSGHEISEKIPQWEHGANWGNDDLPNHQKPYKNGFTENQYCMGFVGKQDEHLRNQAGRDKMSNGWDVLHANEDDPMFNGKYRYSKDHAYNSESNGQAFHGGDHYDAPGHCSSSELYHLPDDFQPYTNCQQVEHFPDSKKEHFQGFAVPEETSKISTEPFQVKYNPYQIKVARMDEMNQDPERRDGNFDDLQREFLDTGENSTGNMQFVQLQVLYKARGRQLEEQNNKLEESERQIRYLNHQLAIVKDQKDGLTISLQESQSLLQNSREMEIQLKGQLTALEKTVESLTTNEEQLRKELNISKVAMESFQQQLLDLRRSESIQRAREQHETVVSMLKKKHEEQVLALQQKLDDVNAMLNEEKELCSRLETRLKLSERKEAESKLEKTDIINRLSKSLEESQKQCANLLQSGSIQEATQLRLQLQQVQSSKIINDGMNKALQEEVRELQEQITMYESAARLGAFVNSGEEQQLSDSYVELGIKNFNWQKSRLGRIVANNGVKNDLSSEEIILELKTELERCLNSNKTKRKQIVQLQAELKGHLLKNEELKKSMEIAERTARDSQIQAENLANKVNNSPFYSSSSDRFREEIQKLQSEKQILQQENEKHLLFIKEFTVNEEKLKASNQELCNEMRGMIQDFDQDKKEAIERCERTYEQHNEDIKAHLLNELYEKFESEKELLSQGYEEKITLLQAQMNEIHREMAAVQECYIAVCKEKDALEENMREHFKKELQKSEEEVTAKAIQDVEMEWAQKLNQALQDAKTKSLQSFETQTIQTDESSLAKSDLNSDCIDELKVKLQNAIQEKEKAVHQAQLELEERHHEETSKQVEVALTRAYGRWLQELTSLPEYKARLKLEQEKWEKTNERNVERQVSDALYAAEIKWKMRSDKVDFTVRQKEFEEKIASMKRELELKAEESQALLKAEIATSRAQWNKEKHDEIQRLREDNEKDYRVFLDEHRNKLTDTLSTAKVEFEKQKNELIAQKDREMAERLDESLKQWALDESRRMRALENEILSEVEQCMYEIHDQLLDKSIVKDRLPSMKSNLDVTFLEKLKACLQKSVKGILYKVLANARQDWKKKYDTESNQETGIRGGELEGSDDRKTAKMWYLDKDLGKTEKQPCCEHWVQQLEKSKKECYEIRSKLEKACRHLQQLVKEQKLKAEKYRKNHILTEELKKQNSELQKKLELTVAPSPACLEPVEGGSNGCMMCNGNALEEIRAQYIKAVDKIKNDMLRYIHESKGRAAELLKSEVLRERQETARKMRKYYLTCLQQLLKDDGNNEGAEKKIINAASKLATMAKVLETPVSQKYQSKSLNSDLPQNENFLSETTQDQRSLQKPAHSHQNNNPLNQNIDQQTIEELIKRHVREKSDGNKVTDAEGASAINENSSFPTLRKSLVDNGNSQFVPSAPFQKLKTFSCIDSSTEGVLVTHQNKQSALQSGTLYPNSEHPKKKPGLQRFDLQETPVRDENGSNDWSCISSKSLFQPHSAKGSLTQLKMGPQNADVEEHSSAVASCSLAEENHNTFSSGARNQHFFAQVAKRKDENSGRKYSNKIQEPSATGIHPESKLFSDVGQGNKLPSRKLLLDFTLSPQQDSGFDSPFPNLNNFN
What is the function of this protein?
Necessary for centrosome duplication; the function seems also to involve cep63, cdk5rap2 and wdr62 through a stepwise assembled complex at the centrosome that recruits cdk2 required for centriole duplication.  Acts as a molecular scaffold facilitating the interaction of plk4 and cenpj, 2 molecules involved in centriole formation (By similarity).  Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles (PubMed:24075808).  Overexpression of cep152 can drive amplification of centrioles (By similarity).
What are the official names of this protein?
Centrosomal protein of 152 kDa, Cep152.
What is the protein family that this protein belongs to?
Belongs to the CEP152 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Colocalizes with cdk5rap2, wdr62 and cep63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (By similarity). Localizes to the deuterosome (PubMed:24075808). Localizes to pericentriolar material (PCM) (By similarity).
Protein: PPNN_ECOL6
Sequence: MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNSGSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLRDILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSINENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPSIIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPANKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMPLVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAFSGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCYEICT
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond of diverse pyrimidine and purine nucleotide 5'-monophosphates, to form ribose 5-phosphate and the corresponding free base.  Can use AMP, GMP, IMP, CMP, dTMP and UMP as substrates.  Cannot catalyze the reverse reactions.  May contribute to nucleoside pool homeostasis by degrading excess nucleotides and feeding back the ribose moiety to catabolism.
What are the official names of this protein?
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, AMP nucleosidase, CMP nucleosidase, GMP nucleosidase, IMP nucleosidase, UMP nucleosidase, dTMP nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: ARSC2_CORGL
Sequence: MKSVLFVCVGNGGKSQMAAALAQKYASDSVEIHSAGTKPAQGLNQLSVESIAEVGADMSQGIPKAIDPELLRTVDRVVILGDDAQVDMPESAQGALERWSIEEPDAQGMERMRIVRDQIDNRVQALLAG
What is the function of this protein?
Involved in defense against toxic arsenate.  Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; facilitates adduct formation between arsenate and mycothiol.
What are the official names of this protein?
Arsenate-mycothiol transferase ArsC2, Mycothiol-dependent arsenate reductase ArsC2.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_AZOSB
Sequence: MSAIVDVIAREILDSRGNPTVEADVLLESGVMGRAAVPSGASTGSREAIELRDGDAARFLGKGVLRAVENVNTEISEAIIGLDAEEQAFIDRTLIDLDGTENKSRLGANATLAVSMAVARAAAEEAGLPLYRYFGGSGPMAMPVPMMNVINGGEHANNSLDIQECMIMPVSMGSFREALRCGAEIFHHLKKITDKKGYPTTVGDEGGFAPNVSGTEEALNLIQEAIAAAGYEPGRDVLLALDCAASEFYKDGKYELKGEGLSLTSEGFTDYLATLADKFPIVSIEDGMAEGDWAGWKHLTDRLGRKIQLVGDDLFVTNTKILEQGIDQGVANSILIKINQIGTLSETFAAVEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAMQIKTGSLSRSDRIAKYNQLLRIEEDLGNTVVYPGKRAFYNLRSR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GATC_MYCA9
Sequence: MSAISRDEVAHLARLARLALTDAELDGYAGQLDAILGHVSQISAVSTDELDEVDATSSPLDAVNVTRPDVIAECLTPEEALAAAPRVAEGRFAVPQILGEEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HRCA_PEDPA
Sequence: MLTDRELLILEEIVREYTENGQPIGSKTLMNNLPVKVSSATIRNDMAKLEEMGLIEKMHSSSGRIPSLMGYRYYVDHLLSPKKLNQSEAQQIQKGLGMHFREVDDIVRTSAEMLSNLTHYTALTLKPDQKDATLDGFRMVPLGGNQVMLILVSSNGDVTSQQFSIPRGMNSETVERVLRIMNDRLIGETLDQVYYHLKTDIPKIVEHYLHSNDGIIDIFENVVAQSSQDRYFIGGKLNILNFSKNVDVSSIRGLLTLFNENDQLDGLLGNNQSDLDVKIGDELSNALLKDFSLITATYDVGSRGKGLIAILGPTSMQYSKTLGLLDTFRDQLSNRMLEYYKHLDDS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YR571_MIMIV
Sequence: MENSTPKKISESQIKNLALSGGGFYGFAVVGALKEIFDNYIDPNNIKTISGVSVGSIIATMLAIGYSIDEITKIMFEIDMDTLIKDSYFSYYTLWEKFGMYNADKLEQEIERIIRDKTHIKNCTFSQIEKNLIIVTTNLNYQRTRIFSKLETPTMIISKAVRMSISYPFIMVPVLFEGDLYGDGGETLNYPITLFDDDLDKTIGITFANHNENDDGTLKTRLPINNFYDYIVSLGLTMNRSSYISQISSKYLDRSIVIKINEDISSMQFNLDLKQKEYLFECGIKSVKQQIIKLINH
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Uncharacterized protein R571.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CEMA_SORBI
Sequence: MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSETFLTDIQEKRILEGFIELEELFLLDEMIKEKPKTHVQKLPIGIHKEIIQLAKIDNEDHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSIKAFFILLVTDFFVGFHSTRGWELLIRWVYNNLGWAPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ARGB_CHLAA
Sequence: MTTISVIKVSGHELDDPTFLGGLTAALRGFQQPLVLVHGGGKEISAAVERAGLQIEFVDGLRVTSPAVMDIMQMVVCGTINKRIVTALVNAGVKAIGLSGLDLGLLRCEPYRPAGRDLGRVGEVTAVDGAALLHLLALGWMPVIAPVALGATDGLSYNVNADMVAEAVAGALAGAELVFVSNVPGVLVDGRVVPALTPAAVEELIANGVISGGMIPKVRAALAALQRGASSVRIVNLAGLHDGGTRFTHGELSE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_YERPE
Sequence: MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRA_STAAS
Sequence: MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVLSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
What is the function of this protein?
Essential helicase.
What are the official names of this protein?
ATP-dependent DNA helicase PcrA, DNA 3'-5' helicase PcrA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: Y2380_SHEDO
Sequence: MFGGKGGMGNLMKQAQMMQDKMAKMQEEIARMEITGEAGAGLVKVTMTGSHSVRKVEIDPSLMEDDKEMLEDLIAAACNDASRRIEENQKNKMAEVTGGMQLPPGMKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Sden_2380.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: UVRB_COXBR
Sequence: MSKAFKLTSKFKPSGDQPQAIEKLVAGLEDGLAYQTLLGVTGSGKTFTIANAIEKVQRPTLILEPNKTLAAQFYAEMREFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDASINDHIEQMRLSATKAITERHDTIIIATVSAIYGLGDPDSYLKMLLHLTRGDQIDQRKILQRLAELQYTRNDLELRRATYRVNGDIIDIYPADSEREAVRVELFDDEVENLSYFDPLTGEMLRRVPRITVYPKTHYVTPREKLLSTLDQIKIELKERLSQLEKANKLVERQRLEQRTKFDMEMILELGYCSGIENYSRYLSGRNEGEPPPTLIDYLPKDALLIIDESHVTIPQLGGMYRGDRARKETLVEYGFRLPSALDNRPLRFDEFEKLAPQTIFISATPGPYEEKQSDQVVELLVRPTGLIDPEIEVRPVATQVDDLLSEIKKRAAQNERVLVTTLTKRMAEDLTEYFTEHNVRVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTMGRAARNVHGKAILYADRITDSMKRAMEEAERRRIAQSAYNEKHHITPKSIQKAVTEIIEGARTYTERGRFVNQAQLIAEEEAKYIAMTPKQLAKELRKLEEQMYHHARNLEFEEAAAVRDKIQHIRKGLLEVKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEMI8_SCHPO
Sequence: MSSEITEGDLQKFHDEHFNAKAVNLWNVAFAQNDRGGNSESANVEYTQSVERYPDGTIRTLTDEQILWFRESEKRELMWKKEKEQLLKEKELRQKALDKERMVSSKPETNPKTPISLKELKDIEIYQNQFHYSAYEILEEEKILDNIFRKFTALPIKYWPATPIRG
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (Probable).  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity).  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate (By similarity).  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity).
What are the official names of this protein?
Uncharacterized protein C16H5.15.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PRSA_LACLA
Sequence: MKFKKLGLVMTTVFAGAALVTLSGCSSSDSASKDIITMKGDTIRVSDLYKEAKQFPSQPTNTLLQNLTFDKIFTKDFGKEVTDKDVSKKVKSIKDQYGSQFSSALQQQGLTEASFTPYMRTQMLEQAAIDHEIKETQYTDANLKKAWESYHPDVTAYVVSETSKDAATKALDAAKKDDAGKASFEKTNAESKVTFNSTSTSVPTEVQTAAFKLKNGEFSDVIESTSSSTGATSYYIVEMVKTSEKGTDMNKYKKELQNVIKTEKEQDTTFVSGVIAKYLKKNNVTVKESAFASLFSQFTQTSSSSSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ATPD_HYDS0
Sequence: MKVNKELARKLSKKIVFSVPKDKESLSAVSDFLGLLGVLYKKEPKFRDFVLSPFVSNEQKKLFIKSLIQKGNIPKEIEFFVDELIDLNLLRIVGEIKRLFDYESEKILSIYKGKLIFAKEPVKELVDEIIQRVEKVLNRKIEPEISVNEALIGGFELRLSGLVLDTSVRSVLQNLSNKVKSL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KDSB_DESOH
Sequence: MKIAAIIPSRYGSTRFAGKPLAPIAGIPMIQRVYDQVKQAICVTDIAVATDDRRIVEAVTRFGGNALMTSAACRSGTDRAAEAAKQMGLAPEDIVVNIQGDQPLIAPQTIDETLAPLLSDPDLGMTTAAFAIMDKQEITNPKDVKMVFDADGFALYFSRSPIPFARDKDTRFDTFKHLGIYAYTRRFLDIFTQLPNGVLEEIEKLEQLRALEHSHRIKTVVTRYDSPEVDIPEDIPRIEAMMASMAAD
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_MAGSA
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTSLTAAITKILAETGGATFTAYDQIDKAPEEKARGITISTAHVEYETSNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFMNKCDMVDDPELLDLVELEVRELLSSYDFPGDDIPIVRGSALCALEDKQPEIGRDAILKLMAEVDAYIPQPERPKDKPFLMPIEDVFSISGRGTVVTGRVERGVVKVGEEVEIVGIKNTVKTTCTGVEMFRKLLDQGEAGDNIGALLRGTKREDVERGQVLAAPGSITPHTDFEAEAYILNKEEGGRHTPFFTNYRPQFYFRTTDVTGVVALPEGTEMVMPGDNVKMIVTLIAPIAMDQGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_VIGAC
Sequence: MSLLSDLINLNLSDTTEKIIAEYIWIGGSGLDLRSKARTLPGPVSDPSKLPKWNYDGSSTGQAPGEDSEVIIYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHNAAKIFSHPDVVAEEPWYGIEQEYTLLQKDVNWPLGWPVGGFPGPQGPYYCGAGADKAFGRDIVDAHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAGDELWVARYILERITEIAGVVLSFDPKPIKGDWNGAGAHTNYSTKTMRNDGGYEVIKSAIEKLGKRHKEHIAAYGEGNERRLTGRHETADINTFLWGVANRGASIRVGRDTEKAGKGYFEDRRPASNMDPYVVTSMIADTTILWKP
What are the official names of this protein?
Glutamine synthetase nodule isozyme, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_BACMK
Sequence: MQYNFKVEAFEGPLDLLLHLINRYEIDIYNIPVAKITEQYLSYVHTMKELQLDVASEYLVMAATLLQIKSKMLLPKQEEDVPDNGEDFIDDPRQELMERLIEYKKYKQVATELKEREQERAQLYTRPPIDFTSFQQEEETSLPLDVTLYDMLAAFQKLMRRKKAKTPVTTRITRQEIPIAQRMTDILQQLEVRGGRQSFYDLFADEEREIMVVTFLAVLELMKNQQIIIEQEHNFDEIFVSSSNKSV
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.