PharMolix/UniProtQA huggingface dataset:
Protein: OTC_HALWD
Sequence: MPKSSNFLDIDDLTTDELQTILDRATALKHGGDNAQFPGQTLGMLFEKPSTRTRISFETGMTQLGGHAIFLGPDDIQLGHGEPLSDTARVLSGYVDVVMARLFNHDDLLEIAAHADIPVINGLTDDAHPCQTLADLLTIKEEFGGFDDVTVVWIGDGNNVGQSFVIGAAMVGLDLTVVTPSGYGMDQSVLDQATALGHPPTIADTPGAAVSDADVVYTDVWISMGQEDQRNEKLTAFEGYQVNESLLANNSAQVMHCLPAHRGEEITDEVLTGTRTLVWDQAENRLHAQKGLLVELLSEN
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSSD1_ECOLX
Sequence: MMLAQKQNFMNQFYKKYHYSIQKYQITDLLFFLFLYPFSTSYGNEQFSFDSRFLPSGYNYSLNSNLPPEGEYLVDIYINKIKKESAIIPFYIKGNKLVPCLSKEKLSSLGININNNDNAECAETSKAGISNISFEFSSLRLFIAVPKNLLSEIDKISSKDIDNGIHALFFNYQVNTRLANNKNRYDYISVSPNINYFSWRLRNRFEFNQNNDKKTWERNYTYLEKSFYDKKLNLIVGESYTSSNVYNNYSFTGISVSTDTDMYTPSEIDYTPEIHGVADSDSQIIVRQGNTIIINESVPAGPFSFPITNLMYTGGQLNVEITDIYGNKKQYTVSNSSLPVMRKAGLMVYNFISGKLTKKNSEDGDFFAQGDINYGTHYNSTLFGGYQFSKNYFNLSTGIGTDLGFSGAWLLNVSRSNFKDKNGYNINLQQNTQLRPFNAGVNFDYIYRKKGYVELSGIGWHGNLYNQLKNSFSLSLSKSLDKYGNFSLDYNKIKYWDNAYDSNSMSIRYFFKFMRAMITTNYSLNKYQSYEKKDKRFSINISLPLTKDYGHISSNYSFSNANTGTATSSVGVNGSFFNDARLNWNIQQNRTTRNNGYTDNTSYIATSYASPYGVFTGSYSGSNKYSSQFYSALGGIVLHSDGVAFTQKAGDTSALVRIDNISDIKIGNTPGVYTGYNGFALIPHLQPFKKNTILINDKGIPDDIALANIKKQVIPSRGAIVKVKFDAKKGNNILFKLTTKDGKTPPLGAIAHEKNGKQINTGIVDDDGMLYMSGLSGAGIINVTWNGKVCSFPFSEKDISSKQLSVVNKQCNRPENSGD
What is the function of this protein?
Involved in the export and assembly of C6 fimbrial subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein CssD, CS6 fimbria usher protein.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y997_SODGM
Sequence: MDHRLLEIVACPVCNGKFYYNKERQELICKSDALAYPLCDGIPVLLESEARAIKLDETNS
What are the official names of this protein?
UPF0434 protein SG0997.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NDK_RICAE
Sequence: MTIQYTFSMIKPDAIKRNKIGQVNTYLENAGLKIVAQKMKFLTKYEAACFYDEHRARPFFNSLVEYITSGAVVLQVLKGEDAITLNRTVMGATNPAEAEAGTIRKDLGESIEANSIHGSDSENSAKREIEFFFNKSEIIE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_AEDAE
Sequence: MSKMMMNGSGTNGTAAVANNHKEMHQRCLNPYRSKVTVVLGAQWGDEGKGKVVDMLATEADVVCRCQGGNNAGHTVVVNGKDFDFHLLPSGIINDKCTSIIGNGVVIHLPGLFDELAKNEAKGLTNWESRLVISNRAHLVFDLHQQVDGLQEAEKGGKSLGTTKKGIGPCYSSKATRNGIRVSDLLGDFKVFSEKFESLVNMYKRLFPNFEVDVASELVRYRDYAERLRPLVRDTVSLVHASLKEGKSVLVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVVGVVKAYTTRVGDGPFPTELHDEIGSLLQKRGGEIGVTTKRVRRCGWLDLALLRYTGMVNGYTSICLTKLDILDTLKEIKVAVSYTLRGEKIDYFPGSITDLAQVEVNYITMPGWLKSTENVRDFNELPPEAQDYIRMIENDLGVPVKWIGVGKGRESIINVKE
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_PSYWF
Sequence: MTKFIFVTGGVVSSLGKGITAASLAAVLEARGLKVTMTKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRHSKMSKTNNFTSGRIYQTVLNKERRGDYLGGTVQVIPHITDEIKHRIHASGEGHDIAIIEIGGTVGDIESLPFMEAVRQMQVELGRNRAMLMHLTLVPYISSAGETKTKPTQHSVKELRSIGLQPDVLICRSEHAIGEENRRKIALFTNVEERAVITCEDADTIYQIPRTLYEQDLDDIICERFGIDAPEADLSDWDKVVDGLLNAQGKVTVAIVGKYVELPDAYKSINEALLHAGITHKTQVEIDYVDAEALETDDSLLARLEQADSILVPGGFGERGKLGKMRAIKFARENKMPYLGICLGMQLAVIEYATNVLGLEADSTEFNRKAAEPIIGLITEWLDEKGELQVRTDDSDLGGTMRLGSQKAELVEGSKLHQIYGAKLITERHRHRYEMNNRYIEPLEQAGMSISGYSAKQHLVESVEIADHPWFIGVQFHPEFTSSPREGHPLFASFVKAAIDHQNI
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DEOC_HALS3
Sequence: MDRETLAARIDHTVLGPTTTRADVLSVVDDAEAHGMNVCIPPCYVADARDHASADRTIATVIGFPHGTQATSVKVAAAEHAHADGADELDLVIPIGRLKGGDHEAVTAEIAAVNDATPLPVKVIIETPVLTDAEKHAACEAAADADAAMVKTATGFTDGGATVPDVSLMSEYLPVKASGGVGTYADAAAMFDAGAVRIGASSGVDIVASFAE
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_VIBVU
Sequence: MSLNFLEFEKPIAELEAKIEALRDVSRHGGDSAIDLDKEIEQLEKKSLELKKKIFSDLGAWETAQLARHPQRPYTLDYVKHVFEEFDELAGDRAYADDKAIVAGIARLEGRPVMIIGHQKGRETREKVKRNFGMPKPEGYRKALRLMKMAERFQMPIITFIDTAGAYPGVGAEERGQSEAIATNLKEMAGLTVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSDKAPQAAEAMGLVASRLKELELIDEIIEEPLGGAHRNHVQMAANMKATLLRQLAELEQFPQDVLLERRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_STAAT
Sequence: MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVERIIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHDVHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGVEGLSPKTRRKYDEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_VIBC1
Sequence: MYMSTDEVRNAFLKFFESKGHQIVESSSLVPHNDPTLLFTNAGMNQFKDCFLGLEKRAYTRATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPADRLLVTVYETDDEAFDIWNKKVGVPADRIIRIGDKKGGKPFESDNFWQMGDTGPCGPCTEIFYDHGEHIWGGRPGTPEEDGDRFIEIWNNVFMQFNRQADGTMEPLPKPSVDTGMGIERISAIMQGVHSNYEIDVFQALIKAAAEVIGYEDLSNQSLRVIADHIRSCSFLIVDGVMPSNEGRGYVLRRIIRRAVRHGNKLGAQGAFFHKLVGVLAEIMGTAGEELKRQQAVVEKVLRIEEENFGRTLERGMAILNEALDNISSQGTDGKVLDGETVFKLYDTYGFPADLTNDVAREREFAIDEEGFEKAMEEQRQRAREAGNFGTDYNAAIKVDTQTEFCGYTGTKGSSSVAAMFVEGNEVESLSAGDKAIIVLGETPFYAESGGQCGDAGEIRTESGVFRVEDTQKLGNAIAHHGVMAEGVLAKGDEVATIVDAERRAAISLNHSATHLLHAALRQLLGEHVTQKGSLVKADGLRFDFSHLEAVTAAELKEVERLVNAQIRRNHVIETNVMDIESAKKKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASSTGDIGLFKITSEGGIAAGIRRIEAVTGEGALDAIEAQAAKYEEKLAESAQKAKSLEKEIQKLKDKMAAAESANIMGKVQDINGTKVLIAALEGADNKNLRTMVDDIKNQVGSGVILLANVNDDKIGLIAGVTKDLIGKVKAGDLVKMVAEQVGGKGGGRPDMAQAGGTDVAALPAAIQTVQPWLEERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTB6_CERNC
Sequence: MADSLVLLTGATGFIGFRILVELLRQGYSVRAVIRSAAKGQWLESRLTAVMKGSDYKDRFQTTIVADFVTDGAFDQAAENTSYIIHVASPIVSSDNPDDWEHDFKRVAVKGSIGVLEAAKRSGTVRRVVITSSMVGLFSPKALFAEPSEVPLNAESRIPEMEPPYAHKMLAYQAGKIASINSAEAWIKHEKPAFDLIHMHPSFVTGRDDLATTREDLRKFSSNWHSMQIVLGHKNPIGKPILTCHNDDVARCHVSALDPKVAGNQSFLISCSPEDGSEWDNVKKIVQREFPEAVAQGVLPNDGHMPTVNKGVRFDVRKTEETFGFKHIPYEAQVLDVVKQYLELPEKDEGVEISTTA
What is the function of this protein?
Ketoreductase; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin (PubMed:17074519, PubMed:15915645, PubMed:26938470).  The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules (PubMed:11701851).  These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids (PubMed:11701851).  The first step of cercosporin biosynthesis is performed by the polyketide synthase CTB1 which catalyzes the formation of nor-toralactone (PubMed:23108075, PubMed:26938470).  The starter unit acyltransferase (SAT) domain of CTB1 initiates polyketide extension by the selective utilization of acetyl-CoA, which is elongated to the heptaketide in the beta-ketoacyl synthase (KS) domain by successive condensations with six malonyl units introduced by the malonyl acyltransferase (MAT) domain.  The product template (PT) domain catalyzes C4-C9 and C2-C11 aldol cyclizations and dehydrations to a trihydroxynaphthalene, which is thought to be delivered to the thioesterase (TE) domain for product release (PubMed:23108075).  The bifunctional enzyme CTB3 then methylates nor-toralactone to toralactone before conducting an unusual oxidative aromatic ring opening (PubMed:17074519, PubMed:26938470).  The O-methyltransferase CTB2 further methylates the nascent OH-6 of the CBT3 product, blocking further oxidation at this site before the reductase CTB6 reduces the 2-oxopropyl ketone at position C7, giving naphthalene (PubMed:17660442, PubMed:26938470).  The FAD-dependent monooxygenase CTB5 in concert with the multicopper oxidase CTB12 are responsible for homodimerization of naphthalene with CTB7 installing the dioxepine moiety, finally producing cercosporin (PubMed:17660442, PubMed:30809363, PubMed:26938470).  The fasciclin domain-containing protein CTB11 might act with CTB5 and CTB12 whereas the roles of CTB9 and CTB10 have still to be elucidated (By similarity).
What are the official names of this protein?
Ketoreductase CTB6, Cercosporin toxin biosynthesis cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: ACYP_DEHMC
Sequence: MHCLRAIVKGKVQGVYFRDFTRTQATRLGLCGYAKNLANGAEVEVVAEGDKDALLEFLDLLRSGPPRAEVKDVETSWETATANYSDFRIKH
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: Y1587_LACP3
Sequence: MATKTYYFYVLLCADGSFYGGFTDDVKARVATHNAGKGAKYTAQRLPVRLLYHQAFADKHDALSAEWHFKHQTRHRKEVFLEDHQVEWR
What are the official names of this protein?
UPF0213 protein LSEI_1587.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: ROT41_LITRO
Sequence: AEILFGDVRPPWMPPPIFPEMP
What is the function of this protein?
Lacks antimicrobial activity.  Does not inhibit the formation of NO by neuronal nitric oxide.
What are the official names of this protein?
Rothein 4.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Rothein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_LEPIC
Sequence: MKSLFLSEKIYVLILAGGTGSRMGSKIPKQFLELNGEPILIHSLKRFQNWGKQKRIVLVSHFESIPKIESICASYLENEDRIVQGGENRHSSMLCGLSVLDFKDEDIILVHDAARPFVLADELDSLCEKVRSDGIATLASRTSETVLEELNGKTVSFLDREHVWFMKTPQGIRGDVLKELLTFSVDSIPTDLCSWALTFGKTSSIVESNPLNLKITRKEDLDLAEVFSSLFQKISSDI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: ACOX_DEBHA
Sequence: MVSATNTVNSGVPPNPAASIQAERAASKFDPKEMHYFLEGGEERAEKFKQMMQQMERDPILSANFQYYDLTKDQQRELTALRIDRLTRYIENESFDDFNKRMSLMGVFDPQLSTRLGINLGLFVSCLKGNGTAEQVKYWAMDKSAVYMRGIYGCFGMTELAHGSNVAGLETTATFDDENDEFIINTPHIGATKWWIGGAAHSATHCSVYARLIVGGQDYGVKTFVVPLRDSNHDTMPGVTVGDIGAKMGRDGIDNGWIQFSNVRIPRYFMLQKFCKVSSEGDVQLPPLEQLSYSALLGGRVMMVLDSFRVSARFSTVALRYAIGRRQFKAGSASDDKNALECQLLDYPLHQRRLLPYLALSYIISASAVKIETTIESTLENLDKAVEADDMGAIMKSIDSMKSLFVDSGSLKSTCTWLAAEVIDQCRQACGGHGYSAYSGFGKAYNDWVVMCTWEGDNNVLAMSVGKQIIKHILGVLDGKKVKGSADFLNNTEQYLNEEPVLRSVDDLKDLKKVLLAIEVAIIRVAYQASQTLKENKGDFDTVGAEMVTLSKLNAHHFMLSEFLDRMDSFESKQLVPYLESVAKLYSATIVLEKFAGDFLAQGVFPPKLNGELNSKHIPELCKEIRPNVIALTDSFQQSDMMINSAIGSYDGNIYENYFGVVKANNPPSKTKAPYSGALEAMLNRPSKEERERFEKSTETAKILSK
What are the official names of this protein?
Acyl-coenzyme A oxidase, Acyl-CoA oxidase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RSMG_STRT2
Sequence: MTPEDFYMALKELGFDLSQKQKDQFQRYFELLVEWNEKINLTAITDKDEVFLKHFYDSLAPVLQGHIKNQSIQLLDIGAGAGFPSLPIKILCPNLDVTIIDSLNKRITFLNFLSDELGLSGVHFYHGRAEDFGQDKAFRAQFDIVTARAVARMQVLSELTIPFLKVGGQLIALKAAAADQELVDARNALNVLFAKPILNENYKLPNGDGRNITIIDKKKETPNKYPRRAGIPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPDF_AZOC5
Sequence: MACAVLIVAAGRGTRAGGAVPKQYHRLGGESVLRRTLLRFAECAAIDVIQVVTHPDDAPLYEQAVAGLTKVLPQVAGGATRQQSVRAGLEALAAYGPERVLVQDGARPFTPPEVIARAIAALDGNTAAIPVLPVTDTIKHVDAAGHVTGTVDRAMLRAVQTPQAFRFAELLAAHRAAADARVADLTDDASVMEWAGHTVATFAGDSENVKLTSAEDLARAARMLADLPDVRTGTGFDVHAFGPGDHVMLGGVAIPFDRGLDGHSDADVGLHALTDAVLGALADGDIGAHFPPSDPQWKGATSDRFLAFAIERVRERGGIVAHLDLTLICEAPKVGPHRDAIRAEIARICDLPLGRVSVKATTTEKLGFTGRREGIAAMASATIRLPLEIGA
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: KAD_HAEIG
Sequence: MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKAGTELGKQAKALMDEGKLVPDELTVALVKDRIAQADCTNGFLLDGFPRTIPQADALKDSGVKIDFVLEFDVPDEVIVERMSGRRVHQASGRSYHIVYNPPKVEGKDDVTGEDLIIRADDKPETVLDRLAVYHKQTSPLIDYYQAEAKAGNTQYFRLDGTQKVEEVSQELDKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBFB_BACSU
Sequence: MKRLHYAWIIVSVTFLILLAVQGVRLSFGAFVEPWERQFSIDRSTISLISTVSFIVYGISQPVIGRLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVAASVLVVNWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPAALLMLRNNPSEKNTEPIGGLAASEKETAPKTTALSVAGMFRMRQFWFLIFPFLICGFTTVGLMDTHLIPFSHDHGFSTTVTSAAVSLLAGFNIAGILLSGIVADRWSSRKILCILYAVRALSIVILIYSHEPYLLLAFAILFGLVDFATVAPTQMLATQYFQNYSIGLMIGWLSLAHQIGSALGAYVPGVIYTVTGEYTLAFYLSIGMLVLASVMNVMLREPAAVTRDSAAVVDK
What are the official names of this protein?
Uncharacterized MFS-type transporter YbfB.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RG1BB_DANRE
Sequence: MPQTTPYSSKFNPSAYSSSHSHRQPVEENYGGLHYRDNKLVSGSLEALIQLLVPTVDYYPDRSYIFTFLLSSRLFLNPFELMSRVCYLGVDHHRVGDPQMDKKRIRDIAPKIVQLLTEWTETFPYDFRDERMMRSLKEMTHRLAFGDELSRRAMQRLIQRLLRKLTTLGQYEESLATTSAAAAIDRPVALKSKQQLVRRDDCVLNLCDDPFIFAQQLTHIEMERLSYIGPEEFVRAFAQKRPSDNHKSFFSKRKASNLEAYVEWFNRLSYLTATEICMPVKKKHRARVLEFFIDVAQECFNIGNFNSLMAIITGMNMNPVSRLKKTWGKVNTDKFDILVHQMDPSSNFYSYRTALRGATQRSSTAHTSQEMIVIPFFSLFIKDIYFLNEGCANRLSNGHINFEKFWELAKQVSEFLSWRQVICPFERDRKTLQYLISAPVFSEDELQLASYESEGPENNLERDTRRSLRSSLSRM
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for Ras family proteins.
What are the official names of this protein?
Ras-GEF domain-containing family member 1B-B.
Protein: PYRD_BURMA
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRMLGAAGRTGLACALSPRVPDAPRTVMGLSFRNPVGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRMFRLPEADAIINRMGFNNSGVDQFVKNVQAARYRGVLGLNIGKNADTPIERAADDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQRRLADLHGKLVPLALKIAPDLDDEQVKEIAATLLRHDIEGVIATNTTLSREAVKGLPHADEAGGLSGRPVFDASNAVIRKLRAELGDAVPIIGVGGIFSGEDARAKLAAGAALVQLYTGFIYRGPALVAECVKAIARGEAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: JERKY_HUMAN
Sequence: MASKPAAGKSRGEKRKRVVLTLKEKIDICTRLEKGESRKALMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNKALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTEPCVFSGGWLWRFKARHGIKKLDASSEKQSADHQAAEQFCAFFRSLAAEHGLSAEQVYNADETGLFWRCLPNPTPEGGAVPGPKQGKDRLTVLMCANATGSHRLKPLAIGKCSGPRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLPEDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNFINPPVPLQGPHARYNMNDAIFSVACAWNAVPSHVFRRAWRKLWPSVAFAEGSSSEEELEAECFPVKPHNKSFAHILELVKEGSSCPGQLRQRQAASWGVAGREAEGGRPPAATSPAEVVWSSEKTPKADQDGRGDPGEGEEVAWEQAAVAFDAVLRFAERQPCFSAQEVGQLRALRAVFRSQQQETVGLEDVVVTSPEELAIPKCCLEASTET
What is the function of this protein?
May bind DNA.
What are the official names of this protein?
Jerky protein homolog.
What is the protein family that this protein belongs to?
Belongs to the tigger transposable element derived protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATG13_PONAB
Sequence: METDLNSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAGEDTGVIYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAALGVGSADLAYPVVFAAGLNATHLHQLMVPGKEGGVPLAPNQPVHGTQADQERLATCTPSDGTHCAATPSSSEDTETVSNSSEGRASPHDVLETIFVRKVGAFVNKPINQVTLTSLDIPFAMFAPKNLELEDTDPMVNPPDSPETESPLQGSLHSDGSSGGSSGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ
What is the function of this protein?
Autophagy factor required for autophagosome formation and mitophagy.  Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.  Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Metazoan subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
Protein: ALR_CAMC1
Sequence: MSEIHLNKAAYIHNLTKICDKAGGKENVIVVLKDNAYGHGARLIASEAKKFGIKNCAVKSECEANEIADIFENILILSHVPTGDESAKFTYAINDIDALLKIKENTKINLAIDTGMHRNGLDISELDYAFEILARRNLELLGAYTHFRASDELNADYFVQRENFSAAKAKILALCDEFGIKKPIFHSHNSAALERASEIKDEMVRVGIAQYGYAQFNGSLNLKPVLSLWAKRVSRRVLKSGQSVGYGAKFIAKDDINVATYDLGYGDGLLRYNGLGELRLANGELILGKISMDSFSCKDSGEWVCVFEDANVWAEFFGTINYDILVKLSPNITRKFI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: THIC_ALBFT
Sequence: MNAPDKFSQLMSLTREPLPASRKIYVPGTQADIQVPMREIMQSNGEAVVVYDTSGPYTDPNANIDVRQGLPSVRSPWIESRGDTESYTGRTPFALDDGLKNGDSESLASLRVQAAGLQRTPRRAKAGANVSQMHYARSGIITPEMEYVAIRENQKLAWMEQYLGNAEREARLAGNSFGANIPKIMTPEFVRDEVARGRAIIPANINHPEVEPMVIGRNFLVKINANIGNSAVTSSIEEEVEKLVWSMRWGADTVMDLSTGRNIHTTRDWILRNSPVPIGTVPIYQALEKVGGVAEDLTWAIFRDTLIEQAEQGVDYFTVHAGVRLAFIHLTANRMTGIVSRGGSIMAKWCIAHHKENFIYSHFDEMTEILKAYDVSYSLGDGLRPGSGADANDEAQFAELRTLGELTQQAWQQDVQVMIEGPGHVPMHMVQANMTEQLKACHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKVGIITYKIAAHVADVAKGHPGVRARDDALSKARFEFRWMDQFNLSLDPDTARNFHDETLPKDSSKVAHFCSMCGPKFCSMKISQEVRDYAKTRGVSEEQALQSGMQTKSEEFRLAGGEMYIPISPA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.