PharMolix/UniProtQA huggingface dataset:
Protein: ALMT8_ARATH
Sequence: MDLNAQEKKAGFFQRLQDFPSKLKDDVTKRVKNVQKFAKDDPRRIIHSMKVGVALTLVSLLYYVRPLYISFGVTGMWAILTVVVVFEFTVGGTLSKGLNRGFATLIAGALGVGAVHLARFFGHQGEPIVLGILVFSLGAAATFSRFFPRIKQRYDYGALIFILTFSFVAISGYRTDEILIMAYQRLSTILIGGTICILVSIFICPVWAGEDLHKMIANNINKLAKYLEGFEGEYFQPEKISKETSSCVREYKSILTSKSTEDSLANLARWEPGHGRFRLRHPWKKYLKIAGLVRQCAVHLEILNGYVLSNDKAPQEFESKIQEPITTMSREVGEALKAIAKSIKTMRNDSACVNAHIDNSKKAIKNLKIALKSSYPETYKDLLEIIPGVTMASILIEVVNCVEKIYEAVEEFSGLAHFKETLDSKLSAEIGQHQLLHRGCVKPVLDGDNEKEDNSSCHVLITVHDEGYLPTATAKNVLGAEKTRVDIV
What is the function of this protein?
Malate transporter.
What are the official names of this protein?
Aluminum-activated malate transporter 8, AtALMT8.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter (TC 2.A.85) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: T64_TERSU
Sequence: MRLLLILVLLTPVIVAFSVDEELNNADGANAASFTADQEVRHKRNLFPAIARRGLDVELKSDGCPKYCPPGISCCFGDNCATSATSGKMECLKNPRQFV
What are the official names of this protein?
Teretoxin Tsu6.4.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1910_ANADE
Sequence: MAGGAGGDGDGRQALGREGEALAAAWLAERGFRILDRNHRTRRGEVDLVCRDGEVLVFVEVRSRTSGAQGGPEETVGPLKGRRVVAAATDWALGHGGLEQAIRFDVVAVTFGDGEPRVEHFPAAFDGDGRPGHW
What are the official names of this protein?
UPF0102 protein Adeh_1910.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: LIPA_ECOBW
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRHL1_XENLA
Sequence: MTQDYDNKRPVLVLQNDGLYQQRRSYTNEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRLSAAKQEHDHADHEHSKRNGLPQINEQALLPDNRVQVLKTVPFNIVVPLANQVDKRGHLTTPDTTAAVSIAHPIKTESQSHCFSVGLQSVFHTEPTERIVAFDRAVPSDHFTSNNQPPNSQRRTPDSTFSETYKEDVPEVFFPPDLSLRMGSMNSEDYVFDSVAGNNFEYTLEASKSLRPKPGDSTMTYLNKGQFYPITLKEIGSNKGIHHPISKVRSVIMVVFADDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDLNDEGKVFISVNCLSTDFSSQKGVKGLPLNLQIDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVQDVKVGLLPTHKRTDITVFKPMMDLDTQPVLFIPDVHFANLQRTTHVLPISPEDMEGELNPGMKRLPFSPEEDFNTPPAKLPRVDEPKRVLLYVRRETEEVFDALMLKTPTLKGLMEAVSEKYEVPIEKIGKIFKKCKKGILVNMDDNIIKHYSNEDTFHLQIEESGGSYKLTLTEI
What is the function of this protein?
Transcription factor involved in epithelial development (PubMed:15705857).  Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' and modulates expression of epidermal-specific genes, including XK81A1 (PubMed:15705857).  Important regulator of DSG1 in the context of epidermal differentiation.  Regulates the maintenance of skin barrier.  No genetic interaction with GRHL3, nor functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity).  Functions downstream of BMP-signaling cascade modulating endogenous bmp4-responsive targets (PubMed:15705857).
What are the official names of this protein?
Grainyhead-like protein 1 homolog, Transcription factor CP2-like 2.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. Grainyhead subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: S41A1_HUMAN
Sequence: MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD
What is the function of this protein?
Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the plasma membrane (PubMed:22031603, PubMed:23661805, PubMed:18367447, PubMed:23976986).  Transporter activity is driven by the inwardly directed electrochemical gradient for Na(+) ions, thus directly depends on the extracellular Na(+) ion concentration set by Na(+)/K(+) pump (PubMed:22031603, PubMed:23661805).  Generates circadian cellular Mg(2+) fluxes that feed back to regulate clock-controlled gene expression and metabolism and facilitate higher energetic demands during the day (PubMed:27074515).  Has a role in regulating the activity of ATP-dependent enzymes, including those operating in Krebs cycle and the electron transport chain (By similarity).
What are the official names of this protein?
Solute carrier family 41 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: SOHB_BUCBP
Sequence: MHFIYDCSLFLFKIVIVIFFIIFVSSIILKISRKKNKNFGILSVSSLNDHYELVKNSIIVQLMDKKTKKLWNKKNKMLKRSTLLTNNNKLIDKDHNIIVVRAQPTLYVIDFKGGIAAHEVKSLREEISSIISVAQKHDEVLLRLESSGGTIHGYGLAAVQLQRLRSRKIFLTISIDKIATSGGYMMACVANYIIATPFSIIGSIGVVAQFPNIHKFLKKNNIDVELHTAGVHKRTLTIFGENTPEDRKKFVEELNVAHDLFKKFVKTMRPSLNIEKLSNGECWFGSIALKKKLVDDINTSDDFIISRIRKFNILHVKFKYNESIIKALFYKKLKTINNLIYKYLNNKLF
What is the function of this protein?
Possible protease.
What are the official names of this protein?
Putative protease SohB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIK_SALNS
Sequence: MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTHRIVLRRHHDPDAPPAHFLRHHRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLANAYAACARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: RPOB_EUCGG
Sequence: MLGDGNEGMSTIPGFNQIQFEGFCRFIDQGLTEELIKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKTSRDMQEQTLFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRLELEIDRKARIWARVSRKQKISILVLSSAMGSNLREILENVCYPEIFLSFLNDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVKGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGQGGSLESPFYEISERSKSKKVRMLYLSPSRDEYYMIAAGNSLALNQRIQEEQVVPARYRQEFLTIAWEQVNLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVTAIAEHEGKIIYTNTDKIILLGNGDTLSIPLVMYQRSNKNTCMHQKPQVPRGKCIKKGQILADGAATVGGELALGKNVLVAYLPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEAHLLRNLDKNGIVMLGSWVEAGDVLVGKLTPQTAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKKGGSNYNPETICVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFSELYEASQQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPKPKDAPESFRLLVRELRSLSLELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_SOLM1
Sequence: MKIAVIGGGSWGTTLADLAAKKGLDARLWVREQAVMNEIRSSRENSWYLPGRKLSDQLEVSTDPAAVAEGVSHFVFAVPCQFIRAAYQRFIKYLPKNAVVICASKGIELDTLMTMSQVCQDALASIKPRFAMLSGPSFAYEVIREMPTAVTLACKDKKAAKDVQEALSTPYFRIYTTTDVRGVELGGAIKNIVAIAAGVADGLGFGGDARAALITRGLHEMSRLGKAMGGDRQTFMGLSGMGDLVLTCTGDLSRNRQVGLRLAKGQKLLDILADMKMVAEGVKTAEAVHALGQKLGVEMPITEQVYAILYKDKDPSKAVYELMTRDLKDE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLE1_YEAST
Sequence: MRFVFDEVFNSDTDSPEFEETCSTTSSTSSQCPTPEPSPAIKLPSFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAASSIIVPHSTNMPLPRASHSSLLDNAKNSNATAPLLEAIEESFQRKMQNLVLANQKEIQSIRENKRRVEEQRKRKEEEERKRKEAEEKAKREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQNEKERQLKKEHEAKLLQQKDKLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTEKGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTSHPFPIALSWHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQASKLLILIGEELTSRMAEKKYVGAARLRILLEAWQNNNMESFPEMSP
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  It is specifically involved in a terminal step of poly(A)+ mRNA transport through the NPC probably by binding the ATP-dependent RNA helicase DBP5 and GFD1 at the cytoplasmic side of the NPC.  These interactions are thought to be important for the dissociation of transport proteins such as the heterogeneous nuclear ribonucleoprotein (hnRNP) NAB2 from exported mRNA.
What are the official names of this protein?
mRNA export factor GLE1, Nuclear pore protein GLE1, Nucleoporin GLE1, RNA export factor GLE1.
What is the protein family that this protein belongs to?
Belongs to the GLE1 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Biased towards cytoplasmic side.
Protein: FLIE_RHIE6
Sequence: MISSVQNVSNLSMTRALGAVDTENSASSSAATMPGTAGAANGVSFASVMGNMASDAVNSLKGAESMSFAGIKGTATTREVVDSMLQAEQTLQTAIAIRDKVVSAFLEVTKMQM
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: GYLR_STRCO
Sequence: MARNIQSLERAAAMLRLLAGGERRLGLSDIASSLGLAKGTAHGILRTLQQEGFVEQDDASGRYQLGAELLRLGTTYLDVHELRARALVWTDDLARSSGESVHLGVLHQQGVLIVHHVFRPDDSRQVLEIGAMQPLHSTALGKVLSAYDPVAHSEALEADRKAFTDRTVCEPDSFEHVLDITRARGYAADVEETWEGIASIAAPIHDRRRMPVGAVGITGAVERLCREGELRPELVAAVRDCARAVSRDLGAGRF
What is the function of this protein?
May be an activator protein for the gylABX operon.
What are the official names of this protein?
Glycerol operon regulatory protein.
Protein: CAS1A_SACS2
Sequence: MVHKVSQREFSRCYKRNCDCICRKPKQRRNVYLNYSLELLITIFKEVIPNLPMDKKIAFVKDYGAYLKVEKGLITCKIKNQVKWSIAPTELHSIVVLTNSSISSEVVKVANEYGIEIVFFNKHEPYAKLIPAKYAGSFKVWLKQLTAWKRRKVEFAKAFIYGKVHNQWVTLRYYERKYGYNLTSQELDRLAREITFVNTAEEVMQKEAEAAKVYWRGVKSLLPKSLGFKGRMKRVSDNLDPFNRALNIGYGMLRKVVWGAVISVGLNPYIGFLHKFRSGRISLVFDLMEEFRSPFVDRKLIGLARESADKVTDLKTVYSLFSDVKEDEIYTQARRLVNAILNDEEYRPYLAK
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: TRPA_RHIEC
Sequence: MTARMDKRFAELKAEGRPALVTYFMGGDPDYDTSLGIMKALPEAGSDIIELGMPFSDPMADGPAIQLAGQRALKGGQTLKKTLQLAADFRKTNDLTPIVMMGYYNPIYIYGVEKFLDDALAAGIDGLIVVDLPPEMDDELCIPAIRKGINFIRLATPTTDEKRLPTVLKNTSGFVYYVSMNGITGSALPDPSLVSGAVQRIKQHTELPVCVGFGVKTAEHAKVIGGSADGVVVGTAIVNQVATSLTKDGKATPDTVQAVATLVRGLSSGARSARLVAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NP1L1_BOVIN
Sequence: MADIDNKEQSELDQDLDDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKVEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDDDSEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ
What is the function of this protein?
Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly.  Participates also in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair.  Stimulates also homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair (By similarity).  Plays a key role in the regulation of embryonic neurogenesis (By similarity).  Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development (By similarity).  Regulates neurogenesis via the modulation of RASSF10; regulates RASSF10 expression by promoting SETD1A-mediated H3K4 methylation at the RASSF10 promoter (By similarity).
What are the official names of this protein?
Nucleosome assembly protein 1-like 1.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Melanosome. Cytoplasm.
Protein: GLMS_STAAC
Sequence: MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STYC_STYCL
Sequence: MQMKATILIVLVALFMIQQSEAGWFGKAFRSVSNFYKKHKTYIHAGLSAATLLGDMTDEEFQEFMQDIEQAREEELLSRQ
What is the function of this protein?
Bactericidal against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Styelin-C.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_SULDN
Sequence: MQRLVEIERFDSEESVEVTLRPSAWNEYIGQEQIKKNLGVFIEASKKRAEALDHVLFYGPPGLGKTTLALIIANEMNANIKVTAAPMIEKSGDLAAILTNLEEGDVLFIDEIHRLSPAVEEILYSSMEDFRIDIIIGSGPAAQTLKIDLPRFTLIGATTRAGMLSNPLRDRFGMNFRMQFYSPEELSKIISQASNKLNKKIADEACSEIAKRSRGTPRIALRLLRRVRDFADVANEKDILHSRAQYALDELGINSYGFDEMDIKLLNLLVGANGRAMGLSTIAAALSEDEGTVEDVLEPYLIANGYLERTAKGRKATPSTYKILNVTMPALDDGGLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MTLD_ARTS2
Sequence: MKAVHFGAGNIGRGFVGLLLHQAGYELVFADVAEELISQLAAADSYDVHEVGDNPTVRTVDNFRALNSATQEADVVAEIATADVVTTAVGPHILKFVAPVIAKGIAARAAGLAPLQVMACENAINATDILRDEVAAQWDPAAGPLEAVAVFANTAVDRIVPNQEPGKGLDVTVETFYEWVIDRTPFGDNVPVIPGATFVDNLEPYIERKLFTVNTGHAAAAYFGFEAGLSKISEAMADQDVAADVRAVLDETKELLIHKHGFNREEQEAYVEKILGRFTNPHLPDTVNRVGRAPLRKLSRHERFIGPAAELAERGIVPEALLGAIAAALRFNDPADAEAAELAQIVASSTAAEATEKVTGLTPGHPLFAAVEALVEEVKAEVKA
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: HBB_CAVPO
Sequence: VHLTAAEKSAILDLWGKVNVGEIGAEALGRLLVVYPWTQRFFEKFGDLSSASAIMSNAHVKSHGAKVLASFSEGLKHLQDLKGTFAKLSELHCDKLHVDPENFRLLGNMIVIALAHHHPSEFTPCTQAAFQKVTAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS11_BURMS
Sequence: MAKASNTAAQRVRKKVKKNVAEGVVHVHASFNNTIITITDRQGNALAWATSGGQGFKGSRKSTPFAAQVAAESAGRVAMEYGVKNLEVRIKGPGPGRESAVRALHGLGIKITAISDVTPIPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: INCA_CHLT9
Sequence: MTTPTLIVTPPSPPAPSYSANRVPQPSLMDKIKKIAAIASLILIGTIGFLALLGHLVGFLIAPQITIVLLALFIISLAGNALYLQKTANLHLYQDLQREVGSLKEINFMLSVLQKEFLHLSKEFATTSKDLSAVSQDFYSCLQGFRDNYKGFESLLDEYKNSTEEMRKLFSQEIIADLKGSVASLREEIRFLTPLAEEVRRLAHNQQSLTVVIEELKTIRDSLRDEIGQLSQLSKTLTSQIALQRKESSDLCSQIRETLSSPRKSASPSTKSS
What is the function of this protein?
Chlamydia replicate within an intracellular vacuole, termed an inclusion.  IncA is probably involved in the homotypic fusion of inclusions.
What are the official names of this protein?
Inclusion membrane protein A.
What is the protein family that this protein belongs to?
Belongs to the IncA family.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (By similarity). Localized in inclusion membrane (By similarity). In the inclusion, the C-terminus faces the host cytosol (By similarity).
Protein: CCME_HAEIG
Sequence: MNPRRKSRFKLVIFVVLGIAIASGLMLYALRQNIDLFYTPSEVIQGKDNNPNQKPEVGQRIRVGGMVVEGTVVRDPKSLKVRFDLNDIGPAITVEYEGILPDLFREGQGIVAQGVLTQSAVLSATEVLAKHDENYVPPELGEKMQKVHKPMGIKAADLKGESERDRQEKEGAK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: MDCC_PSEAB
Sequence: METLTFEFPAGAPARGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQALEEAGHD
What is the function of this protein?
Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
What are the official names of this protein?
Malonate decarboxylase acyl carrier protein, Malonate decarboxylase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the MdcC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_ACIBY
Sequence: MPLIIGIDPGSRLTGYGIIEKDGSKLRFVDAGTIRTETQEMPERLKRIFAGVERIVKFHGPTEAAVEQVFMAQNPDSALKLGQARGAAIAALVNLDLQVAEYTARQIKQSVVGYGAADKEQVQMMVMRLLNLTIKPQADAADALAAAICHAHASGSMSKLTVLNALGGMARGRSRSSSRRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CLPP_SHEPA
Sequence: MHKAPESVLNALVPMVVEQTAKGERSYDIYSRLLKERVIFLVGQVEEHMANLIVAQLLFLESESPDKDIYLYINSPGGSVTAGMAIYDTMQFIKPNVSTVCIGQAASMGAFLLAGGAEGKRHCLPNSRVMIHQPLGGFQGQASDIAIHAQEILGIKNKLNTMLAEHTGQPLEVIERDTDRDNFMSATEAAEYGLVDSVIAKRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.