PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_ALKCK
Sequence: MSKRDYYEVLGVDRNASVEEVKKAYRKLARKYHPDVNKEEDAEAKFKEVKEAYDTLSDPQKKARYDQFGHADPNQGFGGAGASGDFGGFSDIFDMFFGGGGGRRNPNAPRQGDDLQYTMTLEFKEAVFGKETEIEIPREETCGTCHGSGAKPGTKPDTCSHCGGSGQLNVEQNTPFGRVVNRRVCNYCEGTGKIIKQKCATCSGKGKVRKRKKINIQVPAGIDNGQQLRVAGQGEAGANGGPPGDLYVVFQVKPHEFFERDGEDIYCEVPLTFPQVALGDEIEVPTLTGKVKLKIPAGTQTGTSFRLRGKGVPNVHGRGQGDQHVQVRVVTPKNLTENEKELMREFAGMSGGRPEEQNDGFFDKLRRAFKGD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_VIBCM
Sequence: MIGLIGRKVGMTRVFTEDGVSIPVTVVEVEANRVSQVKTLETDGYAAIQVTTGSKKANRVTKPEAGHFAKAGVEAGRGLWEFRLENGEEFAVGSELTVELFNEVKKVDVTGTSKGKGFQGAVKRWNFRTQDMTHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAERVTTQNLEIVRVDAERNLLLIKGAVPGATGGNVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL16_BORDL
Sequence: MLSPRKVKYRKKQRGRLSGEAQKGNKISFGEYGLVSLEADFITARQIEAARVAMTRRVKRGGKVWIRIFPDIPYTKKPAETRMGKGKGGVDHWNAPVKLGTVMFEMSGVPRELAESAMMLASSKLPVKTTFVVRRDLR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ILVD_STAES
Sequence: MRSDMIKKGDHQAPARSLLHATGALKQPTDMNKPFVAICNSYIDIVPGHVHLRELADIAKEAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPNCDKITPGMLLAAVRTNVPAIFCSGGPMKAGLSAQGKALTLSSMFEAVGAFKEGTISKEAFLDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNGTALAVSDQRREMIRQAAFRLVENIKNDIKPRDIITQDAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLERINEIAKKTPYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKDGTLHPDRLTVTGKTLRENNEGKNIKNFDVIHPLENPYDKQGGLSVLFGNLAPKGAVIKVGGVDPSIKVFTGKAICFNSHDEAVEAIDNHTVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAASGGPIGLIRDGDKITIDLINRTLNVNQSEEELYRRKNQLEPFRAKVKTGYLARYTSLVTSANTGGIMQVPENLI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SP5G_GEOKA
Sequence: MEVTDVRLRRVNTEGRMKAIASITLDNEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSATRGKIQEAILAEYHRLGKLEEELEEAGAS
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: PILIN_MYCBP
Sequence: MYRFACRTLMLAACILATGVAGLGVGAQSAAQTAPVPDYYWCPGQPFDPAWGPNWDPYTCHDDFHRDSDGPDHSRDYPGPILEGPVLDDPGAAPPPPAAGGGA
What is the function of this protein?
Structural subunit of pili, which are thin, flexible, coiled-coil, aggregative fibers.  Mediates adhesion to the extracellular matrix, an event that would facilitate direct interaction with the host epithelium during infection in the lung or other tissues (By similarity).
What are the official names of this protein?
Pilin, Pili structural subunit.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial pilin family.
What are the subcellular locations of this protein?
Fimbrium. Note=Part of the pili surface structure.
Protein: ESPB_MYCMM
Sequence: MSQPQTVTVDQQEILNRADEVEAPMATPPTDVPQAPSGLTAANNAAEQLAVSADNVRLYLQAGERERQRLATSLRNAAAAYGEVEDESATALDNDGNGEVDAQSAGGAGAGQTESLEETPKVAAAGESDFTDLKTAATKLESGDQGTSMVNFADGWNNFNLSLQRDIKRFRIFENWEGDAATACEASMDQQKEWILHMAKLSASLAKQANFMAQLQLWARRGHPTLADIVELERLAKDPDYQEQAIKLYAEYQETSEKVLSEYNTKADLEPVNPPKPPAAIKIDPPPPAQPQGLIPGFLMPPGDGSTGLASGMTPPMIPPTGGAGGTPDVNTAELTSAGREAASNLSKGLGVKPMSLGGGGGGLGGMPMGDAALAGGESVRPAAAGDIAGAGQGGGAAGRGMAGGGMGMPMGGAGQGQGGAKSKGAQQDEEALYTEDREWTEAVIGNRRRQDNK
What are the official names of this protein?
ESX-1 secretion-associated protein EspB.
What is the protein family that this protein belongs to?
Belongs to the EspB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS).
Protein: H1C_CHITE
Sequence: MSDPAVETAPVAVASPGKAKKEKKPKSDKPKKPKAPRTHPPVSEMVFNAVKTLKERGGSSLQAIKKFLIAQYKVDVDKLDTFIKKYLKSAVEKGQLLQTKGKGALGSFKLPAAAKKEKVVKKTEKKPKKAAAKPSKAGEKKVKKTIAKKPKAATATKIKKPVAKTTKKPAAAKPAAKKAAPKPKAAPKPKAAPKPKKAAAPKAKKPAAKPKAAKKPAAKKA
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1C.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NRX1A_MOUSE
Sequence: MGTALVQRGGCCLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission.  Function is isoform-specific.  Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission.  Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions.  They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland.  They may affect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery.  Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels.  Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2.  In vitro, triggers the de novo formation of presynaptic structures.  May be involved in specification of excitatory synapses.  Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom.
What are the official names of this protein?
Neurexin-1, Neurexin I-alpha, Neurexin-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Single-pass type I membrane protein.
Protein: ATPB_MYCVP
Sequence: MTATAEKTAGRVVRITGPVVDVEFPRGSVPELFNALHAEISYKDLSKTLTLEVAQHLGDNLVRTISMQPTDGLVRGVEVTDTGTSISVPVGDGVKGHVFNALGDCLDEPGYGKDFEHWSIHRKPPAFADLEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAEFFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGKSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPAVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELAEEDKQLVQRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGDFDHLPEQAFFLIGGLDDLAKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CTU2_CANGA
Sequence: MTAEQCQRCNKNAVEVISRKELFCAECFRVFVMQKQRKQMMSDDYYRDIFKVMYKDKIRSAEEAEQQNKNSTILIPLSFGSSSLMMLDIVHLTLLEQKMQHQKTGFNVDVLICYRESNDELLTNIQSNIKELSTVRYSENKDNIRFHTLCLDSMFEIDKELIDQVVLHNVEFTGRQVSINESEHANLSLQTVLTSCPNRSTKEDIIDFVTKHLVKKYAYQNGQKAILWGHSMTRLADEIISCVVKGRGAQISSKLNTTNLDVNYGSRFKNLYPLKDILLTEVDAYCALFDLSKYLIKYELQDSLLVNKLKKEKHIGNQRLAKNMTINELARKYFNDIEGEYSNVIATVLRTGDKLDEPLATLGEKHCRICKSTVHDDVSKWLRDITVNVGQPLESQLERDLHEKWATSHIGLETTAYYQLRDRVWEQGDDVDLCYGCIVTMQGVKNLNVPWPKNNEQELNEVLAEYSLE
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E2F5_MOUSE
Sequence: MAAAEPTSSAQPTPQAQAQPPPHGAPSSQPSAALAGGSSRHEKSLGLLTTKFVSLLQEAQDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRCLKAEIEDLELKERELDQQKLWLQQSIKNVMEDSINNRFSYVTHEDICNCFHGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSSTSVTPQKSTMAAQNLPEQHVSERSQTFQQTPAAEVSSGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
What is the function of this protein?
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation.  May mediate growth factor-initiated signal transduction.  It is likely involved in the early responses of resting cells to growth factor stimulation.  Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
What are the official names of this protein?
Transcription factor E2F5, E2F-5.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLI4_HUMAN
Sequence: MAALGDIQESPSVPSPVSLSSPGTPGTQHHEPQLHLHGHQHGSPGSSPKVLSQPSDLDLQDVEEVEIGRDTFWPDSEPKPEQAPRSPGSQAPDEGAGGALRSLLRSLPRRARCSAGFGPESSAERPAGQPPGAVPCAQPRGAWRVTLVQQAAAGPEGAPERAAELGVNFGRSRQGSARGAKPHRCEACGKSFKYNSLLLKHQRIHTGEKPYACHECGKRFRGWSGFIQHHRIHTGEKPYECGQCGRAFSHSSHFTQHLRIHNGEKPYKCGECGQAFSQSSNLVRHQRLHTGEKPYACSQCGKAFIWSSVLIEHQRIHTGEKPYECSDCGKAFRGRSHFFRHLRTHTGEKPFACGACGKAFGQSSQLIQHQRVHYRE
What are the official names of this protein?
Zinc finger protein GLI4, Krueppel-related zinc finger protein 4, Protein HKR4.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HH_DROHY
Sequence: MDNQAVSALWSCASATCLSLDAKRHSIEPNPDGQASPDVNNNNNNHNKSTTTVDAHSRKLRHIAHTPRGSCFMALLLLLLLALNFRHAHSCGPGRGLGRRRERNLFPLVLKQTVPNLSEYHNSASGPLEGAIQRDSPKFKNLVLNYNRDIEFRDEEGTGADRVMSKRCREKLNMLAYSVMNEWPGVRLRVTESWDEDRQHGQESLHYEGRAVTIATSDHDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSPSISHMHGCFTPESTALLESGAEKALGELAIGDRVLSMDVKGQPVYSEVILFMDRNLEQVENFVQLHTDGGAVLTVTPAHLISVWQPERQTLNFIFADRVEELDYVLVRDATGELQPQRVLRLGSVQSRGVVAPLTREGTIVVNSVAASCYAVISSQSLAHWGLAPMRLLSTLQSWMPAKGQLRTAQDKSTPKDATAQQQNGLHWYANALYKVKDYVLPKSWRHD
What is the function of this protein?
The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.  Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks.  Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc.  In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu).  Essential component of a signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection.  During photoreceptor differentiation, it up-regulates transcription of Ubr3, which in turn promotes the hh-signaling pathway by mediating the ubiquitination and degradation of cos.
What are the official names of this protein?
Protein hedgehog.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear up to embryonic stage 10 and then at stage 11 shifts to the cytoplasm. Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. SUBCELLULAR LOCATION: [Protein hedgehog N-product]: Cell membrane; Lipid-anchor. Note=The N-terminal peptide remains associated with the cell surface. Heparan sulfate proteoglycans of the extracellular matrix play an essential role in diffusion. Lipophorin is required for diffusion, probably by acting as vehicle for its movement, explaining how it can spread over long distances despite its lipidation.
Protein: MIAA_DESHD
Sequence: MKPLIIIVGPTAVGKTALGVALAQALQGEIISGDSVQVYRKLDIGSAKPTLAEQGNVPHYLLDALDPAEPFTVAQFQTLANQSIQNIQSRGKVPIVVGGTGLYIRSLIDPFQFAEHGSESIRSFWTAFLSEQGKEALHRELAKRDPLSAQRLHPNDTVRIIRALEMCQLTGKPFSEIRGNQDMNYPPLPPSLLYVGLTAPREIIYERINRRCEQMVAAGLIEETHNLIKEGYSPKLKPLQSIGYRHALLYLYGKVTLPEMMRIFQRDTRHFAKRQLTWFRRDPRVVWYDTYSGNLTNILESLIGTCSGMESRVE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL31_METPE
Sequence: MVEKMNEQIYIIPLRDVKRSPRWKRSNTAMKDIRAFLAKHMKSEDVKLDASINEKVWERGSEKPPRKIRVRAMKFDDGQVQAELAQE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: INA1_SHIDY
Sequence: MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGTHQKIIDMAMNGVGCRATARIMGVSLNTILRHLKNSGRSR
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element iso-IS1d protein InsA.
What is the protein family that this protein belongs to?
Belongs to the IS1 elements InsA family.
Protein: CBID_KLEP7
Sequence: MSDQTFDAPVWHHGKALRKGYTTGSCATAAAKVAALMVMRQHLIHQVSIVTPSGVTLCLNVESPHVEGQQAVAAIRKDGGDDVDATHGMLIFARVTLNDSGEISLQGGEGIGTVTRKGIGLPTGSPAINRTPRHTIETAVREAIGPTRGAQVEIFAPEGVLRAQKTYNARLGILGGISIIGTTGIVTPMSEESWKRSLSLELEIKRAAGLERVVLVPGNHGERFVREQMGIDPQMVVTMSNFVGYMIEEAVRLGFRQIVLIGHPGKLIKIAAGIFHTHSHIADARMETLVAHLALLGAPLPLLTLVSECDTTEAAMEHIDAWGYQRLYNHLAERICQRVLEMLRFTQQPPTCDAVLFSFDNQVLGSSRPLAAIARELTC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PPAX_OCEIH
Sequence: MSIRTILFDLDGTLIDTNTLIKASFEHTFKEYNLNFSNEEILKFNGPPLVDTFNKIDETKADRMITTFREHNIREHDNFVTAFPHVYDTLEELQNRNISLGIVSTKMRHTVHMGLELTGISKFFSTIITYDDVTHAKPHPEPVQMAMQKLGAHPEHTLMVGDNHHDIVSGQRANVQTAAVAWSLKDTNYLKSFHPDYIIEDIKDIITIVGDSFA
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: MURQ_DEIGD
Sequence: MTTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVEAALPRLERGGRLVYVGAGTSGRLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGAEDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRAARALGALTIGLANNPGTPLLAAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAKLETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARVALGEG
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: Y1720_SODGM
Sequence: MGWLADYWWVVLLVLAGMLIGGVKALRRVDATSYLKNRPELPPHRDNNAQWDEEDDWPKKP
What are the official names of this protein?
UPF0370 protein SG1720.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PVK2_KARBO
Sequence: SGLQFAVLDGQGFIPFSRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-2, CAPA-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEGU_BREBE
Sequence: MNEQVNENKIQIVIIDDHQLFREGVKRILAMEPEFEVVADGEDGENAVELVEKYNPDVILMDINMPKVNGVEATRDLIQRYPDVKVLVLSIHDDESYVTHVLKTGASGYLLKEMDADALIEAVKVVAQGGAYIHPKVTHNLIKEYRRLVNEDEQESSEIGFKEVEYRKPLHILTRRECEVLQLMTDGYSNRMIGEALYISEKTVKNHVSNILQKMNVNDRTQAVVESIKNGWVKVR
What is the function of this protein?
Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.
What are the official names of this protein?
Transcriptional regulatory protein DegU.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_MYMVV
Sequence: MPKRNYDTAFSTPMSNVRRRLTFDTPLSLPATAGSVPASAKRRRWTNRPMWRKPRYYRLYRSPDVPRGCEGPCKVQSFEAKHDISHVGKVICVTDVTRGMGITHRVGKRFCVKSIWVTGKIWMDENIKTKNHTNTVMFKLVRDRRPFGTPQDFGQVFNMYDNEPSTATVKNDLRDRYQVVRKFQATVTGGQYASKEQAIVSKFYRVNNYVVYNHQEAAKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSISN
What is the function of this protein?
Encapsidates the viral DNA into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  The CP of bipartite geminiviruses is not required for cell-to-cell or systemic movement.
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell-to-cell movement and spread (By similarity).
Protein: PRS6A_CAEEL
Sequence: MSQTPPPKDGKNPEAMEVEDAIDEEILKMSTEDLKSRTHLLDNEIRIMRSEVQRINHSATTLKERIKENTERIKVNKTLPYLVSNVVELLDLEDNTEEEGANVDLDAQKTKCAVIKTSTRATYFLPVVGLVDPDELKPGDLVGVNKDSYLILEKLPAEYDSRVKAMEVDERPTEQYSDIGGCDKQIQELIEAVVLPMTHKDRFVNLGIHPPKGVLMYGPPGTGKTMMARAVAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNDDIKVIAATNRIDVLDPALLRSGRLDRKIELPHPNEDARARIMQIHSRKMNVNKDVNFEELARCTDDFNGAQCKAVCVEAGMIALRRDATEILHEDFMDAILEVQAKKKASLNYYA
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins (PubMed:27528192).  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required (By similarity).  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair (By similarity).  Belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides (By similarity).
What are the official names of this protein?
26S protease regulatory subunit 6A, Proteasome regulatory particle ATPase-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: U390_DANRE
Sequence: MAQGKQKFKAQRPGGAKKHQNKPKGLKKGGRIIAPKKAQVVQQQKLKKGLEVAIRNKIEHEVTQKASTSLHKKLSVLKTPAQKSGTAGAPKPAAGPSK
What are the official names of this protein?
UPF0390 protein zgc136864.
What is the protein family that this protein belongs to?
Belongs to the UPF0390 family.