PharMolix/UniProtQA huggingface dataset:
Protein: SEC13_PICST
Sequence: MVTIGNAHNDLIHDAVLDYYGKRLATCSSDKSINIFDIDGTESYKLVSTLTGHDGPVWQVSWAHPKFGSILASCSFDGKALIWKEQPETQQWSIIAEHSVHQASVNSVSWAPHELGAVLLCASSDGKVSVVDFNDDGTTSHVVFDAHAIGANSASWAPLSSTPSPNQKDAASLKQQRRFVTCGSDNLAKIWKYDAANNTYVEEARLEGHTDWVRDVAWSPSMLVRTYIATASQDRTVLIWTQDKAGKWQKQLLTEDKFPDVCWRCSWSLSGNILAVSGGDNKVSLWKENLQGKWESAGEVVQ
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: CSN3_HUMAN
Sequence: MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
What are the official names of this protein?
COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CSN3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2218_ACIAD
Sequence: MLALISPAKTLDYESTLPTDKHTLPRLLDQSQALIDYCRSLSASEIASLMSVSEKIAKLNAERFQDWTSELTLANARQAIFAFKGDVYTGLDAYHLQENDFEFAQKHLRMLSGLYGLLRPLDLMMPYRLEMGTKLHNSRGHNLYEFWDDRITRLINEDLEQTNSKILVNIASDEYYKSVKEQKINAQIVKPVFLDQKNGKYKVISFYAKKARGLMARFIIENKLENAEDLKAFNSEGYYFDLENSNQHELVFKRDEQA
What are the official names of this protein?
UPF0246 protein ACIAD2218.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL4_FLAPJ
Sequence: MEVKVLNINGKETGRKVQLSDSVFAIEPNKHAVYLDVKQYLANQRQGTHKAKERAEVAGSTRKIKKQKGTGTARAGSAKNPLFKGGGRVFGPRPRSYSFKLNKTVKRLARRSAFSIKAQEANIIVVEDFVFEAPNTKNFINVLKALGLEDKKSLFVLGDSNKNVYLSSRNLKATNVLTNSELSTYAILNANNLVLLEGSLEGIEENLSK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PQQA_GLUDA
Sequence: MAWTAPKITEVPLGAEINSYVCGQKK
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: Y2279_GEOSM
Sequence: MLKHRMTFILVAIAVIFPFIGYLLSFYTDWLFFAETGFSSVFMTTVYAQTGAGLIFGLLLFAFLQLNLHYANKGSFPLSGIYIVGGGDIRINRNEAGRLVRPVGILISLVLAFLAGNWGAMRWEDLLLFANRVTVGMADPVLGKDVGFYLFSLPFVELLKSFAGFMVLAASVLSAAAYYVKGGITLDDRGAGVDPRVRRHLAVLVGLFGLVVAAGFYLESFSLLLSNNGAFHGAGYVDVHGRLMTLRILTFLTPVAGVVLALGIWRGDWRLALGPPVVIVALYLVGVRVYPGLLQKFKVAPNELTLETPYLENHLKFTRYGYDLDKIETVPFDVDTKLSAADIANNDATIKNIRLWDHAPLLKTYSQLQQIRTYYKFFDVDNDRYMVNGQYSQVMLSPRELSYADLPSKNWINERLIFTHGNGITFGPVSRISKEGLPEFFVKDIPAVSLADIKVTRPEIYYGELSNEYVVVKTKVPEFSYPTATGNINTTYAGKGGVPIDSLLKKALFAAQFKTEKILLSSDITPESRIIYNRNIKERVRTIAPFLSFDVDPYMVVDDGGKLKWIVDAYTFSGRLPYSRPVQGGMNYLRNSVKVVVDAYDGTVSFYVSDAQDVMVKVYSRIFPGLFQPISAMPADLRKHVRYPNQYLQVQAAMFAAYHMTDPKVFYNKENLWQVPTLGEKPMEPYYTIMKLPGEKVEEYILLLPFTPSKRDNLAAWLTARCDGENYGKIRAYTFPRDRLIYGPKQIDARINQDSFISQQLTLWSQRGSEVIRGSLLVIPIEKSLLYVQPLFLAADKAGLPELKRVIVAFGDEVVMEENLELALQRLFGARKSIGTAAAAAAPPGAPAAAGQPASSLAKEAMSIYQRALNLQRQGDWSGYGEELRKLEQVLKRMAQ
What are the official names of this protein?
UPF0182 protein GM21_2279.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBF_SYNJA
Sequence: MATKSVNKPDEPVFYPVFTVRWLAVHTLAIPTVFFLGAIAAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SUCC_YERE8
Sequence: MNLHEYQAKQLFARYGMPAPTGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKLVNSKEDIRAFAEQWLGKKLVTYQTDVHGQPVHQILVEAATDIDKELYLGAVIDRSSRRVVFMASTEGGVEIEKVAEETPELIHKVALDPLTGPQPYQGRELAFKLGLTGKQVAQFTKIFMGLATLFLERDLAMVEINPLVITKQGDLVCLDGKLGADGNALFRQPELREMRDKSQEDEREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVFVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAATSLTDAAQQVVAAVGAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: IWS1_CRYNB
Sequence: MSSPALDTIHDQTGEQDLHQEVQAQEHLPVEPTPEVQEEPESDHQDDDEQPEAQVLEQEQEQVAEQERLQDQEDQDQGAELVSQQPTAEEQEETRDELYNEVFGNQGSEASDLSDDEDVRMDEGEKYVPATATSAAKIPKFKKSKRDDEDEDEDEDEDEDDGGERRRKKKKRAERRRQRQEEEDEDEAPVLDEATQRRLALEERIDAIGKKPKAIRRKKKGDDDVDIVDSYHDDICARLRDRMIAAADKDEAANRIKMPGTAKLAMLDEVMGVLRNTTLWQSIVDNGVLEAVKRWLEPLPDKSLPSVGIQKAIFEVLPKMDLDTTTLKECRLGPIVLFYTKTKRVTPAINRQADALVQAWSRPIIKRPANYRSRYIESQNEVEQSQGGGGTGGGYSQSQRGPGERKFKRFDVKKALEENAHRKGARLQIVQDVQYTVAPEPKTHHHAEEMQHVSRIQQDNKKFNRFARQVKTKKH
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YPEA_ECO57
Sequence: MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY
What are the official names of this protein?
Acetyltransferase YpeA.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: Y1890_BURO1
Sequence: MLSPCPILPSAECRDTADTPADPPGRVIPINRRRRRPGDWRPERPRERLLERGPAALTDDELIALLLGTGKPGHDVFVTARALVDQFGTLHGLLEATADDFEAHPGIGPARSARLVAVTEIARRMLVEKAEERMQIDSPGAVEDCLRLKIGTRQYEVFIAVYLDARNRLIDMEEIARGSLTRMAVYPREIVRRAMKHNAAALIVAHNHPSGAVQPSAEDRRLTRVLKDALELVDVRLLDHVVVGVSDTFSFARAGWL
What are the official names of this protein?
UPF0758 protein Bcen_1890.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RS7_PSE14
Sequence: MPRRRVAAKREVLDDPKYGSQILAKFMNHVMESGKKAVAERIVYGALEKVKERKNSDPLEIFEKALDAIAPLVEVKSRRVGGATYQVPVEVRPSRRNALAMRWLVDFARKRGEKSMALRLAGELLDAAEGKGAAVKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RF3_STAAS
Sequence: MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSAFEQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQTKEEVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTR_LISW6
Sequence: MPTPSMEDYIEKIYSLIETKGYARVSDIADELFVHPSSVTKMVQKLDKDEYLIYEKYRGLILTPKGTQMGKRLLERHALLESFLSIIGVDSSHIYHDVEGIEHHLSWNSIDRIGNVVQFFENHPDALEALKAMETTKPETNE
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_CORU7
Sequence: MALSKDEKAATLKEFGLHETDTGSPEAQVALLSARINQLTEHLKDHKHDHHSRRGLLLLVGRRKGLLKYLASTDIERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DAPA_BIFLD
Sequence: MSEHDMHLLDSAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGESPVTHMDEKVELVRAVKEVVDVPVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRPSQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVGTYDRLAELEHVKAVKDATGDLAAAVEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRLANQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_GEOTN
Sequence: MAKTLPIMFQGTHSDAGKSVIATAFCRMFAQDGWKTAPFKSQNMSLNSYVTPDGNEIGRAQGIQAEAAGVAARAEMNPILIKPSREHESQIVVLGKPYGNMQAFAYRNEFFHQGLAVIRQSLETLMNEYDRIVIEGAGSPAEVNLNDRELVNMRVARLANAPVVLIGDIERGGVFASLVGTLALLEPEDRKRVVGVIINKFRGDAALLKPGLDWFEQYTGVPVLGVVPHLPDLAIDAEDSLALERFAASSDDKGAIDIAVIRCPKIANFTDIDPLLTEPDCRVRLVTHAGELGEPDVIVLPGSKNTIEDLMYMKKRGLASRIVSLVNEGKTTVVGLCGGYQMLGDVIRDPHGVETPFPEVKGLGLLPVATTLERTKTTVRSEGMLTWAGERFSVRGYEIHMGRSTPLPGYVPLIEIGGRGEGAKREDGRVLGTYMHDLFHNDAFRTAFFNVIRREKGLASSAVRPFHSLKEAAFDRLAAHVRQHVAVERIEQMMRQFQQR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: METAA_AGRVS
Sequence: MPIKIPDTLPAFDALVHEGVRVMTETAAIRQDIRPLQIALLNLMPNKIKTEVQFARLIGASPLQVELTLVRIGGHKAKNTPEEHLLSFYQTWEEVKHRKFDGLIITGAPVETLPFEDVTYWSEMQQIFDWTQTNVHTTMNVCWGAMAAIYHFHKVPKHGLKEKAFGVFRHRNLAPSSIYLNGFSDDFQVPVSRWTEVRRADIEKVPDLNILMESDEMGVCLVQEDKGNRLYMFNHVEYDSTSLADEYFRDVSAGIPIRLPYDYFPHNDDTLTPLNRWRSHAHLLFGNWINEMYQTTSYDLNDIGKGRGI
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_CAMC1
Sequence: MGSFSIGHWLIVLAIIVLLFGAKKIPELAKGLGKGIKTFKAEMEDTTPEKSEKVEHKEESATSQKIEETTKNA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: C550B_CYACA
Sequence: MFVKMIGWLVLFLFAHQTWAIEVAKDTNGGILNIAPEQLKRGKRLFNSHCSSCHVGGITKTNPNIGLDLESLSLATPPRNNLDALVDYMKNPTTYDGSESIAQIHPSIASSDIFPKMRDLSEDDLYAIAAHILTQPQIQAEKWGGGKIYYTKRSM
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (PSII).  Unlike Synechococcus vulcanus it does not bind by itself to PSII, but requires all extrinsic members of the OEC.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: MNME_LEGPC
Sequence: MSIDTIVAIATPPGRGGVGIVRISGPNAYAIALCLNGNKALQPRLATFCSLYKGNNEVLDQGLVLYFKGPHSFTGEDVIEIQAHGSPVVLDLLIKESIAAGARLARPGEFSERAFLNDKIDLIQAEAIADLIQASSDTAARMALKSLQGDFSKKINQLNEELIYLRMYVEAAIDFPEEEIDFLNDGNVSQLLQRIIGRLEEIRSQANQGVLLREGLSLVIAGRPNAGKSTLINNLAGRDVAIVTEIAGTTRDIMREHILLDDIPLHIIDTAGLRDSDDLVEKEGIKRAWQELKRADCVLLVVDINNPDQQNSLLNELRLTLPNKIPIITVYNKIDTTKLTAKCDEHTVYLSAKTGEGLDELKKVIKQVVGYQPTEGQFLARRRHLQALDEAKALLLTGQSQLTNHKAGELLAEDLRLAHQTLCEITGEFTSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REE1_YEAST
Sequence: MVESKNTELSQGTWLNKPKSVFQEAGKVTLETDEKTDFWRETFYGFTRDSGHFLGVETGSAFTAQVRVQGSYESLYDQAGIMVRIDDGHWLKAGIEISDGHAMLSSVLTNGKSDWSTAVYGGNARDFWLRVTVEKGVLRIQVSSDKKTWPLVRLAPFPTSDHYLVGPMACTPERGGLKVTFSEWSLTAPLGKALHDLS
What is the function of this protein?
Functions in the galactose metabolic pathway via the GAL83 protein and that it may control the level of ENO1.
What are the official names of this protein?
Regulation of enolase protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_ECOLU
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: METAS_VIBPA
Sequence: MPIRIPDQLPASDVLRTENIFVMSETRAASQEIRPLRVLILNLMPKKIETETQFLRLLSNSPLQVNVELLRIDNRPSKNTPTEHLDTFYRQFEMVKGKNFDGLIITGAPLGLVQFEDVIYWDHLKTIMEWAKDHVTSTLYVCWAAQAGLKLLYDLPKKTRKEKLSGVYHHQIHNPFHPILRGFDDTFLAPHSRYADFSPHFLEEHTDLDILATSDVAGVYLATTKDKRNVFVTGHPEYDSHTLHNEYIRDLGEGMEPAIPVNYYPNNNPDNPPIASWRSHGHLLFLNWLNYCVYQQTPYDLDHFSEDAFTKDD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP2_PSET1
Sequence: MDIFNAIILGIIEGITEFLPISSTGHIIVAAQWLGIEATATNQAFGVIIQLAAILAVLANYKDKFTPKHLNLWIKVAIAFIPLGIIAFIFSDVIKALFNVPVVGVMFIVGGVIFLLLERNYKEQNCTTTDVTQVTYKQAIWIGIAQVFALIPGTSRAGSSIVGAMLCGLNRKASAEFSFLLGLPVLAAASGYDLLKHYDLFTFDDLTALAVGFVTSFIVAYFTIKLFIRFLENFTFVSFGIYRIVFGVILLTIAYV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GGGPS_PYRAR
Sequence: MNLYEYLSQGIKHFTLIDPDKSVDYLRIARYALEAGTDGILVGGSLGITASQMEKVVKDIKSVANVPVVLFPGSLSQLTDAADGVLFLSVLNSLDPYFIIGAQVHGAVLIAKHYPRLEVISTAYVIVGDGGAAGFVSMSKPIPYTRPDIATAYALAAGYIGFKALYLEAGSGAPQPVPPDMVRAVRKAFPRVLIVGGGIRSSEVARSIAREGPNVIVTGTLAEESPEKLGEIVRAIKQR
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP54_METKA
Sequence: MIGFADRLAEITKKIKGASIIDEDFVKEVVRDVQRALLEADVDVKLVLELSKRIEKRALEEEPPAGVPKRDYLLRIVYEELVELLGGEKTEGLDIDLSRDVNVIMLVGLYGMGKTTTAAKLARYLQRKGYRVGLVGADPYRPAAGEQLRQLAEEVDVPVHVEDVDDAVEMAVKGVEALKDECDVVIVDTAGRDRLSEDLIDELREMAERIEPHEVLLVLDATVGQKAGDHAEAFHEAVQLTGVVITKLDTAAKGGGALSAVARTGAPIKFVGTGERVDDLEEFNPRSFVARLLGIGDIDELLRRTEEMLEEEEKAEDVLEGEFTLKDLYEQLEALSKMGPVDKLLQYVPGMGGGRNVRKISQITEERLKKYKVIMDSMTEKELENPEILNKSRIRRIAIGSGTSERDVIELLNHYRMMKDVIEDIQSGRIPRIGGELGRVIRNVLRG
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: DED1_BOTFB
Sequence: MADQLNMNGLNLNGGEPRSYIPPHMRGKMGGPAPAGPPANLNGSAWAPQGNGYANGPRPAGGDSWANAPDFTPRGNGAPRGGNNWNPSGPPSFNKNAYGNPAAGAGGPGGAGGAGGAGGGAGQARGGGDGQWRDGKHIAGPANARVERELFGIADDPTKQQTGINFEKYDDIPVEASGQDVPEPVLKFTNPPLDDHLIKNIELAHYKVPTPVQKYSIPIVMGGRDLMACAQTGSGKTGGFLFPILSQAFQTGPSPVPANAAGSFGRTRKAYPTSLILAPTRELVSQIYDESRKFAYRSWVRPCVVYGGADIGSQLRQMERGCDLLVATPGRLVDLIERGRISLQNIKYLVLDEADRMLDMGFEPQIRRIVEGEDMPGVQNRQTLMFSATFPRDIQMLARDFLKDYVFLSVGRVGSTSENITQKVEYVEDIDKRSVLLDILHTHGAGLTLIFVETKRMADSLSDFLINQNFPATSIHGDRTQRERERALEMFRNGRCPILVATAVAARGLDIPNVKHVVNYDLPTDIDDYVHRIGRTGRAGNTGISTAFFNRGNRGVCRDLIELLKEANQEIPSFLENIAREGGGFGGGRGGRSGGRGRGGGANRDFRKFGGGGGGGFNGGGGFGGPPASGGYGGGGGGFGGPPAPSSYGPPPGQYGGGGGGYGGGNGGGYGNPSAGGGGQSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase ded1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTUD1_HUMAN
Sequence: MQLYSSVCTHYPAGAPGPTAAAPAPPAAATPFKVSLQPPGAAGAAPEPETGECQPAAAAEHREAAAVPAAKMPAFSSCFEVVSGAAAPASAAAGPPGASCKPPLPPHYTSTAQITVRALGADRLLLHGPDPVPGAAGSAAAPRGRCLLLAPAPAAPVPPRRGSSAWLLEELLRPDCPEPAGLDATREGPDRNFRLSEHRQALAAAKHRGPAATPGSPDPGPGPWGEEHLAERGPRGWERGGDRCDAPGGDAARRPDPEAEAPPAGSIEAAPSSAAEPVIVSRSDPRDEKLALYLAEVEKQDKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDNWCKQTQVQRKRDEELAKSMAISLSKMYIEQNACS
What is the function of this protein?
Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin.
What are the official names of this protein?
OTU domain-containing protein 1, DUBA-7.
Protein: T2H1_HAEPA
Sequence: MKYEEINFKVPVESPYYPNYSQCVIERIYSILRNQKDMGDDRIIINTNLKKGLPLENINKIAGPMIEAWAEEVFSGIRDNRDNQYNLINVEAQERLGISDIILQFQVNNNVITGNVDVKATSNDIPDSGKSPNITSFSRIRTAYVKDPNFIFIILSIKHSVYVKRNEYTNLMDGIMQIIDFNVYDLKYISDSDISYNPALGTGQIQIKDIHYVSSQKRTTWQMCQLLDLKYLRSKKRTIEQFYNEAKRNKWIKD
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GTTAAC-3' and cleaves after T-3.
What are the official names of this protein?
Type II restriction enzyme HpaI, R.HpaI, Endonuclease HpaI, Type-2 restriction enzyme HpaI.