PharMolix/UniProtQA huggingface dataset:
Protein: MOBA_ECO57
Sequence: MNLMTTITGVVLAGGKARRMGGVDKGLLDLNGKPLWQHVADALMTQLSHVVVNANRHQEIYQAGGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDTPYIPHDLAARLNHQRKDAPVVWVHDGERDHPTIAMVNRAIEPLLLEYLQAGERRVMAFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPA_BOVIN
Sequence: MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYISENLIINTDELGRDCLINAAKTSMSSKVIGINGDFFANLVVDAVLAIKYTDIRGQPRYPVNSINVLKAHGRSQMESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATVLSTLANLEGEETFEASMLGQAEEVVQERICDDELILIKNTKARTSASVILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLPVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGGYEDAVHSGALDA
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit alpha, TCP-1-alpha, CCT-alpha.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GPR55_HUMAN
Sequence: MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
What is the function of this protein?
May be involved in hyperalgesia associated with inflammatory and neuropathic pain (By similarity).  Receptor for L-alpha-lysophosphatidylinositol (LPI).  LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA.  Putative cannabinoid receptor.  May play a role in bone physiology by regulating osteoclast number and function.
What are the official names of this protein?
G-protein coupled receptor 55.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_CUPMC
Sequence: MSIGNIVQCIGAVVDIEFPRDAMPKVYDALVLEEGNDKSFAEKGLTFEVQQQLGDGVVRTIALGSSDGLRRGMSVMSTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIEADEKRAIHQKAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGTEHYEVARRVQQTLQRYKELRDIIAILGMDELSPEDKLAVSRARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: JHAMT_DROME
Sequence: MNQASLYQHANQVQRHDAKLILDEFASTMQWRSDGEDALLDVGSGSGNVLMDFVKPLLPIRGQLVGTDISSQMVHYASKHYQREERTRFQVLDIGCERLPEELSGRFDHVTSFYCLHWVQNLKGALGNIYNLLKPEGGDCLLAFLASNPVYEVYKILKTNDKWSTFMQDVENFISPLHYSLSPGEEFSQLLNDVGFVQHNVEIRNEVFVYEGVRTLKDNVKAICPFLERMPADLHEQFLDDFIDIVISMNLQQGENNEDQKFLSPYKLVVAYARKTPEFVNNVFLEPTHQNLVKGIN
What is the function of this protein?
O-methyltransferase that transfers a methyl group from S-adenosyl-L-methionine (SAM) to the carboxyl group of juvenile hormone acids to produce active juvenile hormones in the corpora allata, the last step during juvenile hormone biosynthesis (PubMed:18549957).  Also able to methylate farnesoate to methyl farnesoate (PubMed:18549957).
What are the official names of this protein?
Juvenile hormone acid O-methyltransferase, Juvenile hormone acid methyltransferase, DmJHAMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RL5_CORJK
Sequence: MSENYTPRLKTRYREEIREKLNGEFSYENVMQIPGVTKVVVNMGVGDAARDSKLINGAIEDLTKITGQKPQIRTAKKAIANFKLREGMPIGARVTLRGDRMWEFLDRLLTVALPRIRDFRGLNDKQFDGHGNYTFGLSEQSMFYEIDVDKIDRPRGMNITVVTTATNDDEGRALLRELGFPFKQKGSAE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: XPT_STRP1
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXL10_HUMAN
Sequence: MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
What is the function of this protein?
Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:7540647, PubMed:11157474, PubMed:22652417).  Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity).  Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization (PubMed:12750173, PubMed:19151743).  In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation (PubMed:12750173, PubMed:12663757).  Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site.  This recruitment is an essential element for neuronal reorganization (By similarity).
What are the official names of this protein?
C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIP_SALTY
Sequence: MRRLLFLSLAGLWLFSPAAAAQLPGLISQPLAGGGQSWSLSVQTLVFITSLTFLPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEQKISMQEALDKGAQPLRAFMLRQTREADLALFARLANSGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLMGSLAQSFYS
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: CATA_IPOBA
Sequence: MDPSKYRPSSSFNTPFCTTNSGAPVWNNTCALTVGSRGPILLEDYHLVEKIQNFTRERIPERVVHARGASAKGFFEVTHDITHLTCADFLRAPGVQTPLIVRFSTVIHERGSPETIRDPRGFAVKMYTRGGNWDLVGNNFPVFFIRDGTQFPDVIHAFKPNPKSHIQENWRILDYLSHLPESLNTFAWFYDDVGIPTDYRHMEGFGVHTFTMINKEGKANYVKFHWKPTCGVKCLLEEEAIRIGGENHSHATQDLYESIAAGNYPEWKLYIQVMDPDHEDRFDFDPLDTTKIWPEELIPLQPVGRMVLNKNIDNFFAENEMLAMDPAHIVPGIYFSDDKMLQARVFAYADTHRHRLGPNYMLLPVNAPKCAHHNNSYDGYMNFVHRDEEVDYFPSKFDNTRNAERFPTPLRIVTGQRDKCVIEKENNFKQPGDRYRSWAPDRQDRFINRWVKALSEPRVTHEIRSTWISYLTQADRSLGQKVASRLNIRPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MIAB_RICRS
Sequence: MSKKLYIKTYGCQMNVYDSIKMQDLLYPFGYEPTENIEEADVIILNTCHIREKAAEKTYSELGRIKKLQDTRTKQGLSSAIIVVAGCVAQAEGEEIFTRTPYVDIVVGPQSYYNLPELISKVVRHEKHLIDLDFVEEAKFDQLPEQLYPQGTSAFISVQEGCDKFCTFCVVPYTRGAEFSRNVEQVYREALKVVSSGAKEIMLLGQNVNAYHGKGPADKIFSLADLLKHLAQIPNLERLRYTTSHPIDMNNDLIKLYGTEPKLMPFLHLPVQSGSNKILKAMNRKHDREYYFDIINRLREARPDIVLSSDFIVGFPGETDEDFEDTLDLVRRVKYGQCYSFKYSPRPGTPGATRTDQIPEHIKSERLTILQQELMAQQLAFNTSCVGSTMKVLFDRNGKFDDQIIGKTPYMQSVYIQNPNKSLLGKIIDVKITKASLNSLTGEIL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYL6_PONAB
Sequence: MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium (By similarity).
What are the official names of this protein?
Myosin light polypeptide 6.
Protein: ASTE_BURPS
Sequence: MTSSADSGRDAAWLDDFLALTLAGDAPPAEAGECAARAVRWRWLGDGLLRLEPADAAQRMQSVLVSAGVHGDETAPIELLSTLVRDIARGALPLRCRLLVALGNPGAMRAGERYLDDDLNRLFGGRHAQLAASREAPRAAQLEAAAALFFSTAGRARGARWHIDMHTAIRASVFEQFALLPHTGEPPTRTMFEWLGEAQIAAVLLHTTKGSTFSHFTAQACGALACTLELGKVMPFGANDLSRFAPADAAVRRLVSGRRDAPRGALPRAFTVVDQITKQSDALELFVANDVPNFTPFARGTLLARDGDYRYAVRHEQERIVFPNPSVKPGLRAGLLVIETTRDTHAALA
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: TRMD_CUPTR
Sequence: MQFDVITLFPEMFRALTDWGITSRAAKQQRYALRSWNPRDFTVDNYRTIDDRPYGGGPGMVMLAKPLDDAIDAAVAAQAQAGVAKPHVVLMSPQGKTLTHAKVMELARRPGLVLLCGRYEAIDQRLIDRRVDEEISLGDFVLSGGELPAMALIDAVVRHLPGVLGDAQSAVQDSFVNGLLDCPHYTRPEEYEGVRVPDILLGGHHAEIEKWRRQQALANTASKRPDLIEAAREQGLLTRADEKFLSEWAAKAGRGETPAR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_YERPS
Sequence: MFEINPVKNRIQDLSDRTAVLRGYLFDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSTLEEIVTTIDQLEQGLEDVSGLLELAVEADDEETFNETIAELEVLDGKLGQLEFRRMFSGEYDRANCYLDLQAGSGGTEAQDWASMLLRMYLRWAESRGFKTEIIEESDGDVAGLKSATVKIIGEYAFGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNKTESAVRITHIPTNIVTQCQNDRSQHKNKDQAMKQLKAKLYEFEMQKKNADKQVLEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGDLDKFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_CLOK5
Sequence: MIKDILNKADEKMNKTVDVLVKELASMKAGRANPAILDKIEVEYYGAMTPISQLAGISIPEARILAIQPWDKSALKSIEKAILKSDLGINPSNDGEIIRLIIPELTEETRKNIVKNIKKTGEDSKVAIRGIRRECNDKFKALKKKNDISEDEIKKGEEQIQKKTDIFIKNIDAILEKKEKEIMSL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_GRABC
Sequence: MEWTAPCIVLSAQPYGEADCLAAVFSEDQGLYRGLVRGGTSRQRGGIWQPGNLVMARWTARLADQLGSLTAELIHPAAALAMDDPLNLAVLRSLCTVAEGALPDREAHPAAFIPLPGLLTRLSLGGGQVVEDAIRWEAILLRELGYGLDLQRCAVTGQVSGLHYVSPRTGRAVSSDAAEPWLDRLLPLPAFLLHQAETDSDPVAWRDGLRLTGYFLSRDVFGTRHRPLPPARMSLYDRIAALTETEREHA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: VF345_ASFM2
Sequence: METFVRLFKDSPQQRSNAWHATRRTQVGGSDLASILGLNPYKSYYITLAEKANLFKKNLNHAACSWGTLFERVSKDLLELFCQTTVIGDNIHIDGTYLGYPGHSNSPDGFCHLTLGYTQQSWEIKTIFNDVCYETTKRIPVLVEIKSPFNRKIKNSVPSYYMPQIQSGLALSPPISMGIYVEAMFRVCSIHQLGWNHETNTDIHPPESMLPLAWGIITICSTQEHTEAPQDFGTLNAEAFHQLLETLYQKNQYTIHYSMPYETACPEMSNVVGYFGWKVFIFQIIPVMKHPQFLKDKYPIIQQFLHDLHTLKTSPSPMEAYEKICCSKESLLSTEDIDDFTNMLT
What is the function of this protein?
Plays a role in the negative regulation of host NF-kappa-B signaling pathway.  Mechanistically, recruits IKKA/CHUK and IKBKB to suppress their kinase activity towards NFKBIA.
What are the official names of this protein?
Protein D345L, pD345L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus D345L family.
Protein: TRUB_SALPA
Sequence: MSRPRRRGRDIHGVLLLDKPQGMSSNDVLQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVQERPVTFSAEQLASALETFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEVHCSKGTYIRTIIDDLGEKLGCGAHVTYLRRLTVSKYPVDRMVTLEHLQTLVAQAEQQGVPAAQWLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTTGAPLKGLVRVTEGEDDKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: QUEF_LEPIC
Sequence: MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVILVSYIPNKRCIELKSFKEYILSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARGGIKTIVTREYKKP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COTV_BACSU
Sequence: MSFEEKVESLHPAIFEQLSSEFEQQIEVIDCENITIDTSHITAALSIQAFVTTMIIVATQLVIADEDLADAVASEILILDSSQIKKRTIIKIINSRNIKITLSADEIITFVQILLQVLNSILSELDVL
What are the official names of this protein?
Spore coat protein V.
Protein: PIKS2_ORYSJ
Sequence: MELVVGASEATMKSLLGKLGNLLAQEYALISGIRGDIQYINDELASMQAFLRDLSNVPEGHSHGHRMKDWMKQIRDIAYDVEDCIDDFAHRLPQDSISDAKWSFLLTKIYELWTWWPRRVIASNIAQLKVRAQQIADRRSRYGVNNPEHLDSSSSARTRAVNYEIAEYQVTSPQIIGIKEPVGMKTVMEELEVWLTNPQAENGQAVLSIVGFGGVGKTTIATALYRKVSEKFQCRASVAVSQNYDQGKVLNSILSQVSNQEQGSSTTISEKKNLTSGAKSMLKTALSLLRGNCICQPENDGNPDNTPIRLQETTDDDQNPRKLEQLLAEKSYILLIDDIWSAETWESIRSILPKNNKGGRIIVTTRFQAVGSTCSPLETDRLHTVDFLTDDESQNLFNTSICESKIRKDSNKVDEQVPEEIWKICGGLPLAIVSMAGLVACNPRKACCDWSKLCKSLFPEQETPLTLDGVTRILDCCYNDLPADLKTCLLYLSIFPKGWKISRKRLSRRWIAEGFANEKQGLTQERVAEAYFNQLTRRNLVRPMEHGSNGKVKTFQVHDMVLEYIMSKSIEENFITVVGGHWQMTAPSNKVRRLSMQSSGSNRGSSTKGLNLAQVRSLTVFGNLNHVPFHSFNYGIIQVLDLEDWKGLKERHMTEICQMLLLKYLSIRRTEISKIPSKIQKLEYLETLDIRETYVRDLPKSIVQLKRIISILGGNKNTRKGLRLPQEKSKKPIKNPSPQGKTKEPAKKGFLSQEKGKGAMKALRVLSGIEIVEESSEVAAGLHQLTGLRKLAIYKLNITKGGDTFKQLQSSIEYLGSCGLQTLAINDENSEFINSLGDMPAPPRYLVALELSGKLEKLPKWITSITTLNKLTISVTVLRTETLEILHILPSLFSLTFAFSLSAAKQDQDIIKDILENNKLDSDGEIVIPAEGFKSLKLLRFFAPLVPKLSFLDKNAMPALEIIEMRFKDFEGLFGIEILENLREVHLKVSDGAEAITKFLVNDLKVNTEKPKVFVDGIVTA
What is the function of this protein?
Disease resistance (R) protein.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
What are the official names of this protein?
Disease resistance protein Piks-2, NBS-LRR class disease resistance protein Piks-2.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: TY1AB_YEASX
Sequence: MESQQLSQHSPNSHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIEKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
What are the official names of this protein?
Transposon TyH3 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1-H3 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLMM_PSEA6
Sequence: MAGLALYCRTGFEKDLANEVVEKCAELNVYGYPELKTNSGLVLFQCYQAEDADKLAKTLPLTTLIFARQLFAFSERCEQLDTSDRIGPILNGCIEFPECGELRVEHADSTQGREISKFCRKISVPLRQALRGKRILTPLERSNLPVCHVYFEDSTTAIVGYSYPANNSSYPLGILRLKFPNEAPSRSTLKLDEAFQLFIPKKEQAKRLSGGLHAVDLGACPGGWTYQLVKRGMFVEAVDNGAMDEALMATGQVRYCPEDGFKFQPRKNNVYWLVCDMIEQPQRVAKLMATWIATKRCQETVFNLKLPMKKRYESVKEALQIIDQCIDQHRAGPYDLKVKHLYHDREEVTVHMRLNT
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBA2_SACS2
Sequence: MTEKLNEIVVRKTKNVEDHVLDVIVLFNQGIDEVILKGTGREISKAVDVYNSLKDRLGDGVQLVNVQTGSEVRDRRRISYILLRLKRVY
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
What are the official names of this protein?
DNA/RNA-binding protein Alba 2.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: NOL11_XENLA
Sequence: MAALSEHFTLCGLLTGTDDGKSEILGVEPAGEPDRVLVTDSVQAVTLYKVSDQKPQGAWAVKQGQSITCPAVLNPESGEFIVVHDDKVLRIWKEDNVNLDIAFKATLSADVCRIHTLPNTDPLVLFKGGAVHFLDSLLTDPQQKIGTVLSDGERIVWSEIFADDGQPLIVYLTQQFSNYFVYIHKFSPVCVCKYHLKPNTEDSTILDCSGSVKSKIFTLLTLYSSGQVCQTPFPVSLINKETERVVSASPLLQLSGPIEVGALNFLDESHVAVLISSSSEQKECLSIWNTTFQTLQAARNFQQRTSAQLWCYDNKLFVPHGKTLVVVPYVCEASCLASVLGKSRNIQTSVLENVPFVNWDKLVGKDPETKPSNAGAQKKTRERKTNANAGNGTESILYPFDVQNISQTQTEAFVQQLLLGKEDTDFQITVGKITQGLVKRCMADPKFYPQSSFVQLVQTNTLSYSLCPDLLSLFLEKRDVPLLQLCLHSFPDVPEVILCSCLKAFLSISEKLVNAAQINTELASLYIDVGDKDKEHKYTEHPEEPSVLQNGFSPTALEEDSCDELIAESLPQTTQKATCPISIKRAVLVNSILISPYNESFLLPHLKDMSGDQVMFFLRYLLYLYLKFNENITINHPGKQMPTVSQIVDWMSMLLDAHFATVVMLSDAKALLNKIQKTVKSQLKFYSEMNKIEGCLAELKELKCPARVSARYSIEVLQLY
What is the function of this protein?
Ribosome biogenesis factor.  May be required for both optimal rDNA transcription and pre-rRNA processing (By similarity).
What are the official names of this protein?
Nucleolar protein 11.
What are the subcellular locations of this protein?
Nucleus, nucleolus.