PharMolix/UniProtQA huggingface dataset:
Protein: HOME2_HUMAN
Sequence: MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
What is the function of this protein?
Postsynaptic density scaffolding protein.  Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3.  By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.  May also couple GRM1 to PI3 kinase through its interaction with AGAP2.  Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459).  Required for normal hearing (PubMed:25816005).  Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway.  Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (PubMed:18218901).
What are the official names of this protein?
Homer protein homolog 2, Homer-2, Cupidin.
What is the protein family that this protein belongs to?
Belongs to the Homer family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Postsynaptic density. Synapse. Cell projection, stereocilium. Note=Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Protein: PYRDA_STRP1
Sequence: MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVTKTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVVGLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTKPLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIKDEQVLIKPKNGFGGIGGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQEGPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC1_BIFLO
Sequence: MAAQIWYENDGDLSVLEGKKVAIIGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVDFAKEQGLEVKSVAEASAEADVIMILAPDQYQRTIWANDIEPNIKPGAAVAFAHGFNIHYGYIKPSEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPRGDGWALTLAYAKALGALRAGAIKTTFKEETETDLFGEQNVLMGGVNKLVEMGFEVLTDAGYQPEIAYFEVCHELKMLVDLMNEGGLNKARWSCSDTAQYGDYVNTVINEDCRKRMEYHLQRIQDGSFAKEFIDDQDAGAPHFKELQEKYSNERIETVGPKLRAMFSWNKDGVKDADEANSFTGKIARAQVQ
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)) 1, KARI 1, Acetohydroxy-acid isomeroreductase 1, AHIR 1, Alpha-keto-beta-hydroxylacyl reductoisomerase 1, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TYSY_AFIC5
Sequence: MHQYQDLLEHILSDGAEKHDRTGTGTLSVFGHQMRFDLAAGFPMLTTKKLPFKAIVHELLWFLAGDTNVRYLQNNGVSIWDEWADANGDLGPVYGKQWRSWQAPDGRSIDQITNLVQMIRTNPDSRRLIVTAWNPADVEQMALPPCHCLFQFYVANGRLSCQLYQRSADVFLGVPFNIASYALLMMMIAQVTDLAPGHFVHTFGDAHLYSNHLDQARLQLTRAPRALPTLRINPAVRDIFGFRYEDFKLENYDPHPHIKAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_STRAW
Sequence: MNTPVIGVLALQGDVREHLIALAAADAVAREVRRPEELAEVDGLVIPGGESTTISKLAHLFGMMEPLRARVRGGMPVYGTCAGMIMLADKILDPRSGQETIGGIDMIVRRNAFGRQNESFEATVDVKGVGGDPVEGVFIRAPWVESVGAEAEVLAEHGGHIVAVRQGNALATSFHPELTGDHRVHGLFVDMVRANRTPESL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RL2_CORA7
Sequence: MAIRKYKPTTPGRRASSVSEFEEITRSTPEKSLLRPLSKTGGRNNYGRITTRHIGGGHKRRYRLIDFRRTDKDGIPAKVAHIEYDPNRTANIALLHYADGEKRYIIAPKGLKQGTIVEAGPNADIKVGNNLPLRNIPTGTTIHAVELKPGAGAKLARSAGASIQLLGKEGKYAILRMPSSEIRRVDIRCRATVGEVGNADQMNIRWGKAGRMRWKGVRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGHKEGRTRNPNRYSNNMIVRRRRPNKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL5_DESAP
Sequence: MSGLKQKYIEEVIPAMMDKFKYRNVMEVPRLEKVVINIGMGEAVQNAKAIDAAMQDLRTITGQQPVVTRAKKSVAAFKIREGMRIGLKVTLRGSRMYDFVDRLINVALPRVRDFRGVSPKAFDGRGNYTLGLKEQLIFPEIDYDKIDKVRGMDITFVTSAKSDEEAREFLRLIGMPLKPH
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FOLD_MYCGA
Sequence: MFIKLDGTKLSQKLKEDLAKKVNNQKIKILIIISDPSEASRIYVRNKINYCDSLGIQTEVYDLSKIDDTNQFIVEMNQKISLSNPNGVLVQLPIKERLDTNKIIENIPIRLDVDAFLYHRFDQDQKEKVIPCVLNAVLELFKEYQLSFLDKKILLIGNGITSNQPIVNYLNEHQIKFDLITKENSQLLEEKTKVADLVISAVGKAKFLANYQFKRGVIFIDIGIDKYFDPEQSKYLICGDFDYDKLKEIASYGTPTPGGIGPLTIYSLVKNLINLSEIQKVNK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RTCB_METMP
Sequence: MKSTVTKIAEKTYQLPVSYKDCMRVPGNVYLDELLFENLQEDVFEQIANVACLPGIQKYSLAMPDCHYGYGFCIGGVAAFDEVTGVISPGGVGFDINCGVRLVKTNLTKNDVTPKLKELLSEIFKNVPSGLGSKGKIRITKDEIDSVLEEGVSWAVEEEYGWERDIKHIEEHGKMKEADPTLVSDNAKKRGLPQLGSLGSGNHFLEVQYVDEIFDEEAAKTFGVSPDQVVLMIHTGSRGLGHQICADYLRYMENAAKKYNIKLPDRQLACAPINSEEGQKYFKAMSCGANYAWANRQLITHWIRESFESVFKTSAEDLEMDIIYDVAHNIAKKEQHLVDGVLKNVVVHRKGATRAFGPGHAEIPSDYVNIGQPVIIPGDMGTASYLMHGTEKAMEQTFGSTAHGAGRALSRVKALKLYTGNEVQEALQKKGILVMADSKGVIAEECPEAYKDIENVADICHDSGISLKVAKMKPMGVVKG
What is the function of this protein?
Essential for tRNA splicing and maturation.  Acts by directly joining spliced tRNA halves to mature-sized tRNAs.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: MATK_PHATN
Sequence: MAELQGYXRLKKDRFRQQNFLYPLLLQEYIYSLAHYHSFNSLIFYEPVEILGYDNKSSLVLVKRLITRMYQQKSLISSVNDSNQKENGFWGHKNSFSSHFSSQMVSEGFAVILEIPFSSRLVSSLEEKRIPKSQNLRSIHSIFPFLEDKLSHLNYVSDLLIPHPIHLEILVQILQCWIKDVPSLHFLRLLFHEYHNLNSILTSKKSIYVFSKRKKRLFWFLHNSYVYECEYLFLFIRKQSSYLRSISSGVFLERTHFYGKIEYLIVVCCNFFQSILWFLKDTFIHYVRYQGKAILASKGTFILMKKWKFHLVNFWESYFHFWFQPYRIHIKKLPNYSFSFLGYFSSVLKNPLVVRNQMLENSFLINTLTKKLDTIAPVISLIGSLSKAQFCTVLGHPISKPIWTDLSDSDILDRFCRIYRNLCRYHSGSSKKQVLYRIKYILRLSCARTLARKHKSTVRTFMRRLGSGFLEEFFLEEEQSLSLIFLQXIPFLLHGLHRERIWYLDIIRINDLVDHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HORM1_CANLF
Sequence: MATAQLQRTSMSALVFPNKISTEQQSLVLVKRLLAVSVSCITYLRGIFPECAYGTRYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECYQFKFKYASNGPVMDFISKNQSSESSMSSADTKKASILLIRKIYILMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDGDCEGVIFEGEPMYLNVGEVPTPFHTFKVKVTTEKERMENIDSAILSPKQLKTPLQKILMDKDDVADEQEHYISDDFDVETKMEEQKRNLGSSELGEPSLVCEEDEIMRSKESLDLSISHSQVEQLVSKTSELDVSESKTRSGKIFQNKMANGNQPVKSSKENRKRNQLESGKTVLYHFDSSSQESVPKRRKFSEPKEYV
What is the function of this protein?
Plays a key role in meiotic progression.  Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends.  Promotes synaptonemal-complex formation independently of its role in homology search.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
What are the official names of this protein?
HORMA domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser- 378 is restricted to unsynapsed chromosomal regions (By similarity).
Protein: PYRF_CAMJD
Sequence: MKLCVALDLSTKEECLQLTKELKNLDIWLKVGLRAYLRDGFKFIEELKKVDDFKIFLDLKIHDIPNTMADACEEISKLGIDMINIHASAGKIAMQEVMTRLSKFSKRPLVLAVSALTSFDEENFFSIYRQKIEEAVINFSKISYENGLDGMVCSVFESKIIKEHTQKNFLTLTPGIRPFGEKNDDQKRVANLTMARENLSDFIVVGRPIYKDNNPRKICEKILQEI
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: M2_I72A3
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: HTR9_HALSA
Sequence: MSKNKHELGSPFTVPLLLNTLDVPAFAVDADGAVVAWDDQIAALLETAPEDAIGVTDIGERLNDDGSRALANKVADTPIDAHHEYDGVGLADESYALLTGDYVYEDTTVAGNTDLWFIATPVYHTGEFRGVIEIVQDRSSSARYQSELQALFGELVDTLDAYDAGRFDATVDIAAEDTLLDDEYIQIGRNLTEFGDTLAAHITEVHNDVERLEAASQAVSESSAEIDELSTAQSTNVSTVATEVETLSATVQEIASTADEVVDTSATAERLADDGSAAASDAADMMADVATAADSVTSDVEALQNRIEDIDEVVDVITGIAEQTNMLALNASIEAARAGEEGEGFAVVAEEVKALAEDAQSNAGHIESLVSEIQRDTADTVTDLVTTTDRIEDAVAQVEDAMASFEEIVTAVEATAEGIEQVSDATNEQAASAEEIAAMVDETADLADDITTAVADIVSQTEAQSAMLHDLDESVSELHDQ
What is the function of this protein?
Potentially involved in chemo- or phototactic signal transduction.
What are the official names of this protein?
Halobacterial transducer protein 9, HTP III.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACLA2_ORYSJ
Sequence: MARKKIREYDSKRLLKEHLKRLAGIDLQILSAQVTQSTDFTELVNQQPWLSTMKLVVKPDMLFGKRGKSGLVALNLDIAQVKEFVKERLGVEVEMGGCKAPITTFIVEPFVPHDQEYYLSIVSERLGSTISFSECGGIEIEENWDKVKTIFLPTEKPMTPDACAPLIATLPLEARGKIGDFIKGVFAVFQDLDFSFLEMNPFTIVNGEPYPLDMRGELDDTAAFKNFKKWGNIEFPLPFGRVLSSTEGFIHDLDEKTSASLKFTVLNPKGRIWTMVAGGGASVIYADTVGDLGYASELGNYAEYSGAPNEEEVLQYARVVLDCATADPDGRKRALLIGGGIANFTDVGATFSGIIRALREKESKLKAARMHIYVRRGGPNYQTGLAKMRKLGAELGVPIEVYGPEATMTGICKQAIECVMAAA
What is the function of this protein?
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives.  May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids.  In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains (By similarity).
What are the official names of this protein?
ATP-citrate synthase alpha chain protein 2, ATP-citrate synthase A-2, ATP-citrate lyase A-2, Citrate cleavage enzyme A-2.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: XYLA_THEMA
Sequence: MAEFFPEIPKIQFEGKESTNPLAFRFYDPNEVIDGKPLKDHLKFSVAFWHTFVNEGRDPFGDPTAERPWNRFSDPMDKAFARVDALFEFCEKLNIEYFCFHDRDIAPEGKTLRETNKILDKVVERIKERMKDSNVKLLWGTANLFSHPRYMHGAATTCSADVFAYAAAQVKKALEITKELGGEGYVFWGGREGYETLLNTDLGLELENLARFLRMAVEYAKKIGFTGQFLIEPKPKEPTKHQYDFDVATAYAFLKNHGLDEYFKFNIEANHATLAGHTFQHELRMARILGKLGSIDANQGDLLLGWDTDQFPTNIYDTTLAMYEVIKAGGFTKGGLNFDAKVRRASYKVEDLFIGHIAGMDTFALGFKIAYKLAKDGVFDKFIEEKYRSFKEGIGKEIVEGKTDFEKLEEYIIDKEDIELPSGKQEYLESLLNSYIVKTIAELR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ACTP2
Sequence: MSNQNSKKHLGHTARKRFGQNFLHDMNVIHNIVSAINPKNGQFLLEIGPGLGALTEPVAEQVDKLTVVELDRDLAERLRHHPFLNHKLTIIEQDALRFNFREYFESLELREGEGVRVFGNLPYNISTPLMFHLFKFHDLIQDMHFMLQKEVVKRLCAAPNSKAYGRLTIMAQYYCQVMPVLEVPPTAFKPAPKVDSAVVRLMPHKVLPHPVKDVYWLNRVTTQAFNQRRKTLRNALSTLFSPEQLEALNIDLNARAENLSIADYARLANWLYDNPPAVDNQEEIIDEDI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_BACAC
Sequence: MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_CYAP4
Sequence: MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: POR_PEA
Sequence: MALQTASMLPASFSIPKEGKIGASLKDSTLFGVSSLSDSLKGDFTSSALRCKELRQKVGAVRAETAAPATPAVNKSSSEGKKTLRKGNVVITGASSGLGLATAKALAESGKWHVIMACRDYLKAARAAKSAGLAKENYTIMHLDLASLDSVRQFVDNFRRSEMPLDVLINNAAVYFPTAKEPSFTADGFEISVGTNHLGHFLLSRLLLEDLKKSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAGGLTGLNSSAMIDGGDFDGAKAYKDSKVCNMLTMQEFHRRYHEETGITFASLYPGCIATTGLFREHIPLFRTLFPPFQKYITKGYVSEEESGKRLAQVVSDPSLTKSGVYWSWNNASASFENQLSQEASDAEKARKVWEVSEKLVGLA
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase, chloroplastic, PCR, NADPH-protochlorophyllide oxidoreductase, POR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYRM_YEAST
Sequence: MFGIVYLKNRSLLCKNPFSSYPRYGFMPSFDTQFSNQFRKLEINIGRKRYSSKTLNTKYTDQPEGPIYPLDVLRLDISKALHDISGIDHSLILNALESTNSMDRGDLLLPLPKIKVADPVAVANRWAIELSTHGCIGKVCAKGPFLQFFLDQRYLIQSTVPNILLQKGKYGQKKSRHQKKVVVEFSSPNIAKPFHAGHLRSTIIGGFLSNLYEAMGWSVTRMNYLGDWGRQFGLLAVGFKRYGDEKTLQKQPIQHLFDVYVKINMDLAKEEINGNSKCGISGEARSFFKNLENGDENAIKIWNRFRSLSIHHYIQTYSRLNINFDIFSGESQVSKESMNEALDIFRKNNLVKEIDGALVIDLTQWSKRLGRVVVQKSDGTTLYLTRDVGAAIERKKNLHFDKMVYVISSQQDLYMSQFFMILKKMNFEWAKDLQHINFGMVQGMSTRKGNVVFLDTILDEARDKALQIMENNKMKISQVDNPQRVADLIGVSAIIIQDMKSKRINNYEFNWNRMLSFEGDTGPYLQYTHSRLRSLERTSSDFTTDMLIHADFSNLNEPQLVELVRLLAQYPDVLRRAFETQEPATIVTYLFKVCHQVSSCYKKIWVSGKPADIAIPRLAVYSASRQVLHNAMSLLGLVPVDRM
What are the official names of this protein?
Arginine--tRNA ligase, mitochondrial, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IBP1_SHEFN
Sequence: MNHSIKKTYLVFTMLLGFILLAGCNGDNNNDNSNNDNNGVLLTSIAVTPATPSMPLGLKQQFTAMGTYSDGTSSDITNSATWSSDDSTVATINGSGLAMGVIPGSVAITASLIDSSSNEQSATTTLTITDATLTALAITPVNPSLAKGLTKQFMATGTYSDGTSPDVTTSVTWSSANTLVATVNASGLASGVAIGSSIITASLGSDETTTELNITDAILSSIALTPVEPSIAKGITQQFTAIGTYSDGISVDITASSNWSSADTLVATMNTSGAAKGVSIGSSIITADFQAQSATSLLTVTDASLTSIMLTPANPHIPKGNTLQLTATGIYSDGISVDITSSAIWSSADTLIATVNADGVVSGITSGSAIITATSAALSATTTVTVTDTTLTSIAVTPGNQTIVKGSNKQLTATGTYSDGSLANITASVTWSSADTLVATVNNSGLASGIETGSSLISASSGALSGSTNLTITGAALNSIVVSPTNLSLVKGMNKQFAATATYSDGSVADISTSVTWSSADTLVATIDVNGLANGKAAGSSLITATSGAQSNSTNLTVTDATLNSIDVTPINPSIIKNSSQNFVATGHYSDGSTTNITSTVMWSSADTLVATLNPNEQLNSGRATAIEVGSSVIQASLSGVFADTTLNVTAALPNNPLAPELGEVARFAMLASQAITTTSGSAIVDGDLGILDQARSYYAGFTPGVNAGEFDELTNGLSYAGDDSTPPYVVPVPYASMVAFINQSRTDLGIAYNFLAADPNPNAATQVCPIELGNLTLTRGVYKTAADVTLQTGTLTLDGEGDPDSVFIFTIGGNLTSGAPGGDIVLINGAQAKNIYWRTAGKTVIGTNTNFSGNVFAWSEVNVRTGANVTGRLFAVTDQVTLDANAVTKAN
What is the function of this protein?
Ice-binding adhesion protein that adsorbs this bacterium onto ice to maintain a favorable position in its aquatic habitat.  Inhibits growth of the ice crystals.  Has high thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point.  The TH activity of this protein is approximately 1. 4 degrees Celsius at 25 uM and little below 2 degrees Celsius at 80 uM.
What are the official names of this protein?
Ice-binding protein 1, Antifreeze protein 1, AFP 1, Ice adhesin 1.
What is the protein family that this protein belongs to?
Belongs to the ice-binding protein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Extracellular side.
Protein: LSRF_SALTY
Sequence: MADLDDIKDGKDFHTDKPQTNTLFALKGCGALDWGMQSRLARIFNPKTRKTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPPAINKPVVLRASGANSILTELSNEAVAVAMDDAVRLNSCAAAAQVYIGSEHEHQSIKNIIQLIDAGLRVGMPIMAVTGVGKDMARDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIAAGCPVPIVIAGGKKLPEREALEMCYQAIDQGASGVDMGRNIFQSEDPVAMIKAVHAVVHHNETAERAYELFLSEKS
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.