PharMolix/UniProtQA huggingface dataset:
Protein: BIOB_BACCQ
Sequence: MKQVQTKRDWKKLAYDVVEEKVITKEDAIAILEADDTEILEIMNAAYIIRHHHFGKKVKLNMIINTKSGLCPEDCGYCSQSIISEAPIDKYAWLTQEKIVEGAHEAIRRKAGTYCIVASGRRPTDKEVNHVIGAVKEIRETTDLKICCCLGFLNEDQAGRLAEAGVHRYNHNLNTHANNYESICSTHTYDDRVDTVQKAKQAGISPCSGAIFGMGETIEERAEIAFELQRIDADSIPCNFLVAVKGTPLEGQKELTPVECLKVLAMMRFVNPTKEIRISGGREINLRSVQPIGLFAANSIFVGDYLTTAGQEPTADWGMIEDLGFEIEECAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: UVRB_XYLF2
Sequence: MTGLFQLVSSYSPSGDQPAAVQKLVTNFHAGIAKQVLLGVTGSGKTYTIANVVEQIQKPTLVMAPNKTLAAQLYGEFKAFFPHNAVEYFVSYYDYYQPEAYVPASDTFIEKDSSINEYIEQMRLAATKALLSRSDVLVVATVSAIYGLGAPEDYLSLRLILSLGEHIEQRQLIRHLTELQYTRNELDLVRGSFRVRGEVVDVFPAESEMEALRIELFDGEIESLSLFDPLTGQTVRKLQRFSVYPKTHYATTRERTLSAVDTIKDELKEYLELLYGRNKLVEAQRLAQRTQFDLEMMAEVGYCNGIENYSRHLTGKAPGEPPPTLFDYLPPDALLVIDESHVTIPQIGAMFKGDRSRKETLVEFGFRLPSALDNRPLRFEEWEVRSPRSIYVSATPGSYEFRESAGEVIELLVRPTGLIDPEIEIRPVATQVDDLISQINACIKLGDRVLVTTLTKRMAENLTEYLSEQGIRIRYLHSEIDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSTSSLIQTIGRAARSVRGRAILYADKVTRSMRAAIDETERRRQKQKEYNAENGIVPKSVVRPISDILEGARDGVEVKSKGKGRRVDEVPADYGALNQAEIAAQMKVLEQKMYQHARDLEFEDAARIRDQIQRLREAGLG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GARL_ECO27
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: COW_DROME
Sequence: MKHSPLIASACLALVLMSSSLIGSTEARNKKKYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMADSKKRRQHSQKSKAHFPPACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAGAYAPDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTSDDEDEGADDEDSAEGSADQMLVF
What is the function of this protein?
Binds to the Wnt signaling protein wg, stabilizes it and promotes its extracellular distribution.  This is required for establishment of a wg gradient during development to allow for regulation of target genes at different levels.
What are the official names of this protein?
Proteoglycan Cow, Carrier of wingless, Carrier of wg.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN598_HUMAN
Sequence: MAAAGGAEGRRAALEAAAAAAPERGGGSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFATIPIHQLQHEKKYDIYFADGKVYALYRQLLQHECPRCPELPPFSLFGDLEQHMRRQHELFCCRLCLQHLQIFTYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCDERYLDNDELLKHLRRDHYFCHFCDSDGAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHRTACHSRSRAEARQNRHIDLQFSYAPRHSRRNEGVVGGEDYEEVDRYSRQGRVARAGTRGAQQSRRGSWRYKREEEDREVAAAVRASVAAQQQEEARRSEDQEEGGRPKKEEAAARGPEDPRGPRRSPRTQGEGPGPKETSTNGPVSQEAFSVTGPAAPGCVGVPGALPPPSPKLKDEDFPSLSASTSSSCSTAATPGPVGLALPYAIPARGRSAFQEEDFPALVSSVPKPGTAPTSLVSAWNSSSSSKKVAQPPLSAQATGSGQPTRKAGKGSRGGRKGGPPFTQEEEEDGGPALQELLSTRPTGSVSSTLGLASIQPSKVGKKKKVGSEKPGTTLPQPPPATCPPGALQAPEAPASRAEGPVAVVVNGHTEGPAPARSAPKEPPGLPRPLGSFPCPTPQEDFPALGGPCPPRMPPPPGFSAVVLLKGTPPPPPPGLVPPISKPPPGFSGLLPSPHPACVPSPATTTTTKAPRLLPAPRAYLVPENFRERNLQLIQSIRDFLQSDEARFSEFKSHSGEFRQGLISAAQYYKSCRDLLGENFQKVFNELLVLLPDTAKQQELLSAHTDFCNREKPLSTKSKKNKKSAWQATTQQAGLDCRVCPTCQQVLAHGDASSHQALHAARDDDFPSLQAIARIIT
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation (PubMed:28065601, PubMed:28132843).  Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3 (PubMed:28065601, PubMed:28132843).  Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843).  Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:22751931).
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNF598, Zinc finger protein 598.
What is the protein family that this protein belongs to?
Belongs to the ZNF598 family.
Protein: MRAZ_RALSO
Sequence: MFQGASALTLDAKGRMSIPTRHREALQLQAEGRVTVTKHPDGCLMLFPRPEWERFRERIAALPMEAHWWKRIFLGSAADVELDTAGRVLITPELRLAATLERDVMLLGMGSHFEIWDAATYTAKEQAAMAQGMPDALKNFSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ORF1_CHRSD
Sequence: MQQLSKRRLSALFVTAFLPVTAFASECSSVRFAEVGWTDITVTTALASEVLEALGYEPRVDTVSVPIAYAGIRNNDFDVFLGNWMPSMASISDPYIERGEVERLVANLEGAKYTLAVPQYVYDAGVTSVNDLAEHADQFEQRIHGIEAGNDGNEL
What are the official names of this protein?
Uncharacterized protein ORF1.
Protein: ALDH1_TANCI
Sequence: MSSGANGNSKSLAYDIKFTKLFINGEFVDSISGSTFETIDPATEEVLATVAEGREEDVDLAVKAAREAFDNGPWPRLSGEARRKILLKFADLIEENADEIATLEVIDTGKPFQIARYVENSWTSETFRYFAGAADKIRGATLKMSSDFQAYTLREPIGVVGHIIPWNAPAYLFAMKVAPALAAGCTVVIKPAENTPLVGLFMAYLSKLAGVPDGVINVVNGFGSTAGAAVSSHMDIDAVTFTGSTKVGRTIMQAAAASNLKPVSLELGGKSPFIVFDDADIEKAAEIAVLGVLSNKGELCVAGSRVFVHEGIYDAFVKKLEATVKNWATGDRFDAATRHGPQNNKQQYEKVLSYIELGKKEGATLVTGGKPFGNKGYYIEPTLFTNVTDEMTIAKEEIFGPVIMVLKFKTIEEVIRRANATTYGLAAGIMTKNIDIANTVTRSIRAGSVWVNCYLALDRDTPFGGYKMSGFGREQGLEALEHYLQVKTVTTPIYNSPWL
What is the function of this protein?
Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide (PubMed:30468448).  Mediates the conversion of trans-chrysanthemal into trans-chrysanthemic acid (PubMed:29122986).  Can also use octanal, hept-2-enal, dodecanal, citral, farnesal, citronellal and perillyl aldehyde as substrates (PubMed:29122986).
What are the official names of this protein?
Aldehyde dehydrogenase 1, TcALDH1, Trans-chrysanthemic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DBP9_VANPO
Sequence: MSSSEVLAPEAYIDDSISFESLQLDTRLLQAIKRNGFKNPTLIQSHAIPLALQEKRDIIAKAATGCGKTLAYLIPVIQTILDYKKTNTDKIDGTSNTLGIILVPTRELAQQVNDVLDKMILYCSNDIRSLNISSDMPSSVLTSLLLEKPEIIIATPGKLMTLLDTNVESVSLEELKFLVIDEVDLVLTFGYKEDLSKIAEYLPLKKNLQTFLMSATLNDDIQELKKEFCRAPAILKFNDDEISKDKNKLIQYYVKTSEFDKFLLCYVIFKLGLIKGKTLIFVNNIDRGYRLKLVLEQFGIKSCILNSELPANSRQHIVDQFNKNVYHLLIATDDTEYIKEEDEENDDEIETNSEEQDKVEDSNDTKDKKGKKASKIKKDKEFGVSRGVDFQNVACVLNFDLPTTAKSYVHRIGRTARAGKTGTAISFVVPLKEFGKHKPSMYQSTKRDEKILSRIIKQQSKLGLELQPYSFDTKQIEGFRYRMEDGFRAVTQVAIREARVKELKDELLASEKLKRHFEENPQELQSLRHDKELHPSRVQQHLKRVPDYLLPAEAREGKKKVGFVPFHSVKKSNRHKKNNKVFKKRSGSKSDPLKNFK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GRPE_GEOUR
Sequence: MEKKKHGTNSISEALKVKAAVEQETATPEPTPQSETESADKIKQLEEALAAKEAEAAANWDKVLRERADLENYRKRVQKEKEELLKYGNESLILEILPAIDNMERALEHACDESMSAIVEGIKMTLCMLQSTLKKFGVAPVDAGKGTTFDPAYHQAMNQVESSEHEPNTIVSEFQKGYLLNERLLRPALVSVATAPKEQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_SALPA
Sequence: MFEINPVNNRIQDLTERTNVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAIVDTLDQMTQGLDDVSGLLELAVEADDEETFNEAVAELNTLEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLLRMYLRWAEARGFKTEVIEESEGEVAGIKSATIKISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIDINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDTKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_STRPJ
Sequence: MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TORC_ECOLI
Sequence: MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
What is the function of this protein?
Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA.  Acts by transferring electrons from the membranous menaquinones to TorA.  This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal domain of TorC, then from the N-terminus to the C-terminus, and finally to TorA.  TorC apocytochrome negatively autoregulates the torCAD operon probably by inhibiting the TorS kinase activity.
What are the official names of this protein?
Cytochrome c-type protein TorC.
What is the protein family that this protein belongs to?
Belongs to the TorC/TorY family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: G3P_METTH
Sequence: MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKLFGEAGIPVSGTVEDMLEEADIVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSFNSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKKVRAVMVRRGADPVQVKKGPINAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKARLDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVHQESDAVPESVDAIRALLELEEDNMKSIMKTNRAMGIL
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_FRATT
Sequence: MIVSTKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVTAVDYLTYGQSDWQVGKVVSQTGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCKLKDAQIILVDSVSDLWPSANWAEREVYDMFGIYFNNHPDLRRVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROC_PSEU2
Sequence: MSGNTFGKLFTVTTAGESHGPALVAIVDGCPPGLELDLQDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGKTTGASIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLGPIQIPFKTWDSVEDNAFFCPDPDKVPELEAYMDQLRRDQDSVGAKITVVADGVMPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFDCVAQRGTEHRDEMTPQGFLSNHAGGILGGISSGQPIIAHLALKPTSSITTPGRSIDVDGNAADVITKGRHDPCVGIRATPIAEAMMAIVLLDHLLRHRGQNADVSVNTPVLGQV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CCS_DICDI
Sequence: MDDKNLEIKVELNVDISCQSCVDSISKELREKLENTKLVEHDIPEQRIVLQGTDLTQDILETIKNTGRNATICGLSSTTTTTSTSPSSSTCHKKQETVSGSAVCSLGLIENWQKGCGGSGGVGSKGVYGVIRLLRASTTKTLFEGRITGLKPGKHSLVVHEFGNLMNGCDDLGEPFISNVENNNNNNNNNNNNNNNNNNNNNNNNNNNKNINKCKEILNKIIGTSDVKQDGKAEFRVLSDKYDFWDLIGRSIVLHSQDSKYSPIEDLNNNNNNKNIVNSESDKILGERVACGIISRAASIGQNHKKVCPCDGTTAI
What is the function of this protein?
Delivers copper to copper zinc superoxide dismutases.
What are the official names of this protein?
Probable copper chaperone for superoxide dismutase, Superoxide dismutase copper chaperone.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS1_XYLBA
Sequence: DFLFARTMIGVFKNIEIMCNKGSSQTWGKEAWKKIVVCIVSDRRAKINPRTRAVLAGLGVYQDGIAKQQVNGKDVTAHIYEYTTQVGIDLKGTQVSLRPKGATPVQLLFCLKEKIRRKINSHRWFFQAFGRVLDPNICVLIDAGTKPGKDSIYHLWKAFDLEPMIGGACGEIKVMLEHGKKLYNPLVAT
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTL_FERNB
Sequence: MSVIKKLPQEVVSKIAAGEVVINPASVVKELVENSLDANATSIEVQIRNGGKSYIKVSDNGIGMSRDDMLIAIDRFTTSKISALEDIYNIHSYGFRGEALSSIAEVSRLIITSSDGNNAHRLEVIGGKIIKITETHRERGTTVEVYDLFFNIPARRKFLSSEKVETRMVTEIVEKFMLVQPSVSFVFKIEDEIVYNASKGSLEDRFSIIFPEVKEFSLIEPLQSEIMQISGIISSPQYTRRNRSGQIFFVNKRFVIDNLLNLSFERGYGEALAQGEHPYGVIFLDFLPDKIDVNIHPQKLQVKFSDPQNVYNEIARTIRTTLRKFSFFQMSISKNSEEEEKYSSEISNQNLKAENYQHTDSEWYPNQFKNLYQKETPQTYRPYEPLSSISQNLLLPQLNEKSLPKEFIVLKDRYIVFEDLDGLVIIDFHAAHERIIYEQLKENKFETVQLLIPLHIKLGKSFLQLSQQLTDEFKKYGFDFEIKTLEDGSGEVVIKQIPSILKVTDASNVFLEVLEEYRIPFEKPKGLTYVLASKACKSAVKTGDKLSHDEVQQIIKEIKSKNLLTCPHGRPIMMKLSFSQLDSFFERI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SELK_MOUSE
Sequence: MVYISNGQVLDSRNQSPWRVSFLTDFFWGIAEFVVFFFKTLLQQDVKKRRGYGSSSDSRYDDGRGPPGNPPRRMGRISHLRGPSPPPMAGGUGR
What is the function of this protein?
Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (PubMed:21220695).  Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity).  Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (PubMed:23444136).  Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed:25368151).  Plays a role in protection of cells from ER stress-induced apoptosis (By similarity).  Protects cells from oxidative stress when overexpressed in cardiomyocytes (By similarity).
What are the official names of this protein?
Selenoprotein K, SelK.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein K family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single- pass membrane protein. Note=Probably mainly localized in the ER.
Protein: ECM23_YEAST
Sequence: MLYNKEQGTSGASSSGRRTKFHFDRFVQMVLFIAANPNYCCSVASIPKSGVTPDLKRADILEQKIKSLNSALSPKLKEESRLGGPLHNPSILPAPSFSSLPISSNGKKSLAGYRPKSRKKQTILPNGQPKECATCGDTWTSQWRSGPNGNVELCSRCGIAYRKKMEKKIRSQQSSDDGTKNFIFKNK
What is the function of this protein?
Involved in morphogenesis.  May be involved in cell wall organization and biogenesis.
What are the official names of this protein?
Protein ECM23, Extracellular mutant protein 23, SRD1 homolog 2.
Protein: Y011_NPVOP
Sequence: MSLSSKLLVYAYYGSYNLPHDRYGESYHLYRIVHEHLTNTYVSNASCVRRDIATARCLNSGHLCFDVARQLLDVSEVAARLSAWFRCGDATGLCADMQRALADIDRHAPLARRVGRRANIFALDAIADIPSDVTNNLQGIIGRFMHFPRCSGLARVADVFDPDIRADGWWYHKFCVLTYMHLVACGAVPAGSATRLRDAVAKHIGPNDEGNCAPAIAAVYGRFCAIGREHFAHHKTACMHILFQFMRNDLTPADERHPCFGVIKDFGRQCKDTYTDLRTHADALYIHGTTDRQKNALFDLLCCVNASDIDADCYDCVVNKFYATQNKKYKM
What are the official names of this protein?
Uncharacterized 37.2 kDa protein, ORF11.
Protein: RL27_BACAC
Sequence: MLRLDLQFFASKKGVGSTKNGRDSQSKRLGAKRADGQTVSGGSILYRQRGTKIYPGVNVGRGGDDTLYAKVDGVVRFERLGRDRKQVSVYPVAQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: OTC_SULDN
Sequence: MGKLLRHFLTLRDFSKDEILEIINIGLEIKKSLKSAVCKHELKNQTLAMIFEKSSTRTRVSFETGMFQLGGHALFLSNRDIHLGRGEPVKDTARVISGMCDMIMIRTFEHSRIEEFASYSKVPVINGLTDSYHPVQLLADYMTLVEYGMEKNIIAAYVGDGNNMTHSWMMLAAKLGFELRVATPKGYEVDEKILQEALLIAKESGAVIKVTNDPSEAVKGATVVTTDTWTSMGQEEEKEARIRIFNGFMVDEKMMSQAASNAKFLHCLPAYRGLEVSEEVFEKHSEIIFNEAENRLHAQKGLMVWLDKQRNI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIF1L_PONAB
Sequence: MSGELSNRFQGGKAFGLLKARQERRLAEIDREFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKANESSPKPVGPPPERDIASLP
What is the function of this protein?
Actin-binding protein that promotes actin bundling.  May neither bind calcium nor depend on calcium for function (By similarity).
What are the official names of this protein?
Allograft inflammatory factor 1-like, Ionized calcium-binding adapter molecule 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with F- actin. Partially relocates to membrane ruffles in response to invading bacteria (By similarity).
Protein: CAIA_SALTI
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCTFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBID_MYCBT
Sequence: MSGTPDDGDIGLIIAVKRLAAAKTRLAPVFSAQTRENVVLAMLVDTLTAAAGVGSLRSITVITPDEAAAAAAAGLGADVLADPTPEDDPDPLNTAITAAERVVAEGASNIVVLQGDLPALQTQELAEAISAARHHRRSFVADRLGTGTAVLCAFGTALHPRFGPDSSARHRRSGAVELTGAWPGLRCDVDTPADLTAARQLGVGPATARAVAHR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.