PharMolix/UniProtQA huggingface dataset:
Protein: COX3_GAZSP
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDVVRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL33_HERAR
Sequence: MAKSGRDKIKLESTAGTGHFYTTTKNKRTTPEKMSIIKFDPKVRKHVEYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: FABZ_PSYA2
Sequence: MPLTYHTLKHYLPHRYPFLLVDKIVACTPGECITGIKNVTINEEFFNGHFPDEPIMPGVLMVECMAQVSGVLGFISAGLTAEDGYLYLFAGVDKVRFKRRVIPGDQLIIRSKIVMQKQGIYKFDCTVHVEDELAVSAQIMIARQEQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPT1_BOVIN
Sequence: MAAAQEADGAGSAVVAAGGGSSGQVTSNGSVGRDPPAETQPQNPPPQPAPNAWQVIKGVLFRIFIIWAISSWFRRGPAPQDQAGPGGAPRVASRNLFPKDTLMNLHVYISEHEHFTDFNATSALFWEQQDLVYGDWTSGENSDGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQKALYRRLATVHMSRMINKYKRRRFQKTKNLLTGETEADPEMIKRAEDYGPVEVISHWHPNITINIVDDHTPWVKGSVPPPLDQYVKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQLYAAQSAKSPWNFLGDELYEQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKNDIQFWNSRQSLEGLSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRLDREHKVAGLLPRPTFQDKSTYVESSTKVYDDMAFRYLSWILFPLLGCYAVYSLLYLEHKGWYSWVLSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGCLRDDVVFFIYLYQRWIYRVDPTRVNEFGMSGEAPTAAAPVAEAPPAAGALSSAPSPTTTTEAAREEASTPPPSQAPQGPSSASEPQEAPPKPAEDKKRD
What is the function of this protein?
Involved in GABAergic but not glutamatergic transmission.  Binds and traps GABAA receptors in the endoplasmic reticulum (ER).  Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors.  Altered GABAergic signaling is one among many causes of cleft palate (By similarity).  Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one (By similarity).  Required for efficient glycosylphosphatidylinositol (GPI) inositol deacylation in the ER, which is a crucial step to switch GPI-anchored proteins (GPI-APs) from protein folding to transport states (By similarity).  May play a role in T-cell development (By similarity).
What are the official names of this protein?
Putative lipid scramblase CLPTM1, Cleft lip and palate transmembrane protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLPTM1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HRH3_CAVPO
Sequence: MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
What is the function of this protein?
The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system.  Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist).
What are the official names of this protein?
Histamine H3 receptor, H3R, HH3R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BGAL_FELCA
Sequence: MDFPGAARLLSLLLVPLLLGPARGLRNASQRTFKIDYGHNRFLKDGQPFRYISGSIHYFRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPQPGQYQFSGEHDVEYFLKLAHELGLLVILRPGPYICAEWDMGGLPAWLLLKESIILRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPIITVQVENEYGSYFTCDYDYLRFLQRRFRDHLGGDVLLFTTDGAHEKFLQCGALQGIYATVDFGPDANITAAFQIQRKSEPRGPLVNSEFYTGWLDHWGQPHSRVRTEVVASSLHDVLAHGANVNLYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTDKYFALRDVIRKFEKVPEGFIPPSTPKFAYGKVALQKLKTVEDALNVLCPAGPIKSLYPLTFIQVKQYFGFVLYRTTLPQDCSNPTPLSSPLNGVRDRAYVAVDGVPQGVLERSYVITLNITGQAGATLDLLVENMGRVNYGRYINDFKGLISNLTLGSSVLTDWMIFPLDTEDAVRSHLGGWHGRNHGRQDNKAFAHHSSNYTLPAFYAGNFSIPSGIPDLPQDTFIQFSGWTKGQVWINGFNLGRYWPGRGPQVTLFVPRHILVTSAPNTIMVLELERAPCDDNGPELCTVEFVDRPLISATPTSSHPLPDLSDRDSGWDRV
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Beta-galactosidase, Acid beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: NAGC_ECOL6
Sequence: MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQLAPASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITLFDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDPDSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFNPQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKRAMLNGILLQHLLEN
What is the function of this protein?
Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon.
What are the official names of this protein?
N-acetylglucosamine repressor.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: PGLRX_ASPNC
Sequence: MRLTHVLSHTLGLLALGATAEAFSRSREAACSPKKPFRPLPTSSSRDKTCHVRSHGDGSDDSDYILSALHQCNHGGKVVFDEDKEYIIGTALNMTFLKNIDLEVLGTILFTNDTDYWQANSFKQGFQNATTFFQLGGEDVNMYGGGTINGNGQVWYDLYAEDDLILRPILMGIIGLNGGTIGPLKLRYSPQYYHFVANSSNVLFDGIDISGYSKSDNEAKNTDGWDTYRSNNIVIQNSVINNGDDCVSFKPNSTNILVQNLHCNGSHGISVGSLGQYKDEVDIVENVYVYNISMFNASDMARIKVWPGTPSALSADLQGGGGSGSVKNITYDTALIDNVDWAIEITQCYGQKNTTLCNEYPSSLTISDVHIKNFRGTTSGSEDPYVGTIVCSSPDTCSDIYTSNINVTSPDGTNDFVCDNVDESLLSVNCTATSD
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase X, ExoPG, Galacturan 1,4-alpha-galacturonidase, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_STAS1
Sequence: MDNLLSTEYLNTTEIYDLIQRASAFKNGNAQPGCFEDKFVANLFFENSTRTKSSFLVAEQKLGLKLIDFETSTSSVQKGESLYDTCKTLEQIGANVLVIRHSQTTYYDELKHLNIPIINAGDGSGQHPTQSLLDLMTIYEEYKTFEGLNVLICGDVKNSRVAKSNYQSLTALGAHVMFSSPDEWKDETLEAPYVDIDEVIDRIDIVMLLRVQHERHEDSEVTSFEVSQYHENFGLTQSRYDLLKDRAIIMHPAPVNRGVEIEDTLVEAPKSRIFKQMENGMYIRMAVIDHILQTEGATAK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MURA_PROM0
Sequence: MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLTDIEKMANILRNLGVKIVEKNNRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEAKVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANIKGDKSRLIGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGCSHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINCNKIKGVDIETAPFPGFPTDLQAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIKLNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGTSTISGLEHLDRGYENFESKLKILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAP1_PLRVW
Sequence: MTPMRITVWRKRLQQMRPQRKLLKQTQQRRLLHQLQQRKLLQQTSL
What is the function of this protein?
Seems to play a role in virus replication.
What are the official names of this protein?
Replication-associated protein, Rap1.
Protein: FLPA_NANEQ
Sequence: MHMPKNIKVKPHKLEGVYIGNNKFLLTKNLVKGQKVYTERIFKSKGEEYREWIPFRSKLASAIKKGLKTWPFKKGTIVLYLGIASGTTASHISDIIGEEGIIFGVEFAPRVLRELMFVAKKRKNIVPILADANQPETYQHIVVQSDVIYQDVAQPHQVEIFLKNLRFFAKPNAIGFLAVKARSIDVTKDPKVIFREVERKLREAKLQLLESIRLDPYHKDHMMFVVKVPKAW
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: GSIB_SALPA
Sequence: MTQFITHKWLAALGLASSIAAFPALAAKDVVVAVGSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKDMKVKNVLAEGYTVSDDGLTYTITLRQGVKFQDGADFDAAAVKANLDRASNPDNHLKRYNLYKNIAKTEVVDPVTVKITLKQPFSAFINILAHPATAMISPQALEKYGKDIGFHPVGTGPYQLETWNQTDFVKVKKFSGYWQQGLPKLDSITWRPVTDNNTRAAMLQTGEAQFAFPIPYEQAALLAKNKNLELVASPSIMQRYISMNVTQKPFDNPKVREALNYAINRQALVKVAFAGYATPATGVVPPSIAYAQSYQPWPYDPAKARELLKEAGYPDGFSTTLWSSHNHSTAQKVLQFTQQQLAQIGIKARITAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTQFNTALYSNKQVDSDLAAALKTNDPQEKTRLYKEAQDIIWKESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFDDADLK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Binds glutathione.
What are the official names of this protein?
Glutathione-binding protein GsiB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BGAL_GEOSY
Sequence: MNVLSSICYGGDYNPEQWPEEIWYEDAKLMQKAGVNLVSLGIFSWSKIEPSDGVFDFEWLDKVIDILYDHGVYINLGTATATTPAWFVKKYPDSLPIDESGVIFSFGSRQHYCPNHPQLITHIKRLVRAIAERYKNHPALKMWHVNNEYACHVSKCFCENCAVAFRKWLKERYKTIDELNERWGTNFWGQRYNHWDEINPPRKAPTFINPSQELDYYRFMNDSILKLFLTEKEILRGVTPDIPVSTNFMGSFKPLNYFQWAQHVDIVTWDSYPDPREGLPIQHAMMNDLMRSLRKGQPFILMEQVTSHVNWRDINVPKPPGVMRLWSYATIARGADGIMFFQWRQSRAGAEKFHGAMVPHFLNENNRIYREVTQLGQELKKLDCLVGSRIKAEVAIIFDWENWWAVELSSKPHNKLRYIPIVEAYYRELYKRNIAVDFVRPSDDLTKYKVVIAPMLYMVKEGEDENLRQFVANGGTLIVSFFSGIVDENDRVHLGGYPGPLRDILGIFVEEFVPYPETKVNKIYSNDGEYDCTTWADIIRLEGAEPLATFKGDWYAGLPAVTRNCYGKGEGIYVGTYPDSNYLGRLLEQVFAKHHINPILEVAENVEVQQRETDEWKYLIIINHNDYEVTLSLPEDKIYQNMIDGKCFRGGELRIQGVDVAVLREHDEAGKV
What are the official names of this protein?
Beta-galactosidase BgaB, Beta-gal, Beta-galactosidase I, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: GLP1R_HUMAN
Sequence: MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
What is the function of this protein?
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449).  Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449).  Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).
What are the official names of this protein?
Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA2_MYCUA
Sequence: MRPLTIIGPTGTGKSDSAIEIADRLSSKIAVEIVNADAYQLYRGMDIGTGKVPLAQRRGIPHHQLDVLDVTETATVAGYQRSAAADIEAIASRGALPLLVGGSMLYVQSLLDDWAFPAKDPAIRARWERRLAQVGPARLHADLVRRDPAAAAVIPLNDARRTVRALEVVEITGRPYAASAPRIGSPRWDSAIIGLDCETKVLDERLAARTKAMFDRGLIEEVISLLPCGLARGVTASRALGYAQVMEALKAGADTQALDRARQQTCLATRRYVRRQRSWFRRDRRVRWLDATVSTAAHRTAIIEAVLGAWRRAS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: D104A_PANTR
Sequence: MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Beta-defensin 104A, Beta-defensin 4, BD-4, DEFB-4, cBD-4, Defensin, beta 104, Defensin, beta 104A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFAS1_CANGA
Sequence: MVALKYVLVPVALVAAKNIVEMITFRDENGKLHRRLAPEEYRGGVLDGEESRLLQKRDLEMHPPVDLGVYFSNRPIHRTIDVPDIYLDSQISVLTELDIFASYSRNDEKSYDMFRDPESDLIVIAPTNAAITALAKKPWQFPMDIDTMEQAGSSERDIDNAIHNNIVNFVRSHVVAYQKDTKTSKDGTVLLQSKQYSMQHSNGKGGDVLLKREGEKYCVASVVDEVFHDVQNIYSTKNGVILVIDATLSRPGA
What are the official names of this protein?
FAS1 domain-containing protein CAGL0M08734g.
What are the subcellular locations of this protein?
Vacuole.
Protein: IKA1A_XENLA
Sequence: MRKLHLDSLTLQLRSDLQCIKASSSSLCDQMDCMLRVLQDLKRSSPPPSPDIEKTCAVPQRRVPRRDNRISHRTSDLSEADSACCMDLPSDVSPGSCGQRGLEWDSGYSEVSGSSLRGEEDDIVEEESETRAPAVVLRRLPTPSCQRLSSGGFLNSRQGRIRPKSTSDVCLEQWRGIGLGSDSQDWTGCLLSQSRSRQPLILGDNSFADLVKQWMDLPENGDEEGRRVRDGGRWLHKPHGFLISLSGNVKRRLGNMSRLRHSDQEAVKRMSCPQLGCRPLSPYYHQSLSDIAEASTNLLNCRSRRPIICNEGAGFL
What is the function of this protein?
Inhibitor of the serine/threonine-protein kinase pak4/pak5 (By similarity).  Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity (By similarity).  Required for the proper migration of neural crest cells during embryonic development, probably by inhibiting pak4/pak5 (PubMed:17314132).
What are the official names of this protein?
PAK4-inhibitor inka1, Induced in neural crest by AP2-alpha protein A, IncaA.
What is the protein family that this protein belongs to?
Belongs to the INKA family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: BGALC_TALMQ
Sequence: MFFFRFLTTVLLLFNAKLLVAQSSNTSSPVHWDKYSLSINGERLFVFAGEFHYIRLPVPELWLDVFQKLKANGFNAISVYFYWNHHSASEGVYDFETGGHNVQRLFDYAKQAGVYIIARPGPYANGELSAGGYALWAANGRLGGERTRDSQYYDLWSPWMTKIGKIIAANQITEGGPVILVQHENELQETTHRANNTLVLYMEQITQILDAAGIVVPSTHNEKGMRSMSWSMDYEDVGGAVNIYGLDSYPGGLSCTNPNAGFNLIRTYYQWFQNYSYTQPEYLAEFQGGYFTPWGGVFYDDCASMLQPEYADVFYKNNIGNRVTLQSLYMAYGGTNWGHIAAPVVYTSYDYSAPLRETREIRDKLKQTKLLGLFTRVSPDLLQTEMEGNGTSYTTGANIFTWALRNPETNAGFYVVAQDDSSSTTDVVFDLEVETSAGSVNITNIGLDGRQSKIITTDYKVGDTTLLYCSADILTYATLDVDVLALYLNKGQTGTFVLANAASHLKYTVYGNSTVTSSNSSQGTIYTYTQGQGISAIKFSNRFLVYLLDKYTAWDFFAPPLQLSDPNVKPNEHIFVIGPYLVREATIKGRTLELTGDNQNTTSIEIYHGNPFITSITWNGKHLSTKRTAYGSLTATIPGAEAITITLPKLTSWKSHDMIPEIDPEYDDSNWVVCNKTTSFNAIAPLSLPVLYSGDYGYHAGPKIYRGRFGSTNATGVTVTAQNGNAAGWSAWLNGIYIGGVTGDPSIEATSAVLKFNSSTTLKQEGSENVLTVLVDYTGHDEDNVKPARAQNPRGLLGVIFEGSTSTNFTSWKLQGNAGGEKNIDALRGPMNEGGFYGERLGWHLPGFEPSTKSGWDTRAPSDGVDGGSHRFYITEFTLDLGPNSHALDVPIGIHLNASSTSGPAVAYVWLNGYKFAHYLPHIGPQTVFPFQPGVLNIQGSEGHKRKNTLAVSLWALTDQPAALDVVELVAYGKYTSSFDFARDWSYLQPRWVDRSKYA
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Probable beta-galactosidase C, Lactase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND1_GLOVI
Sequence: MLRTVLLSKIHRATVTGACLEYMGSISLDAQLLAAAHILAFEQVHVVNLNNGARLITYAIEATAGSGAVVLNGAAARLAAPGDRVIVLAYGQGTTEELENHQPRVVHVDTGNRIVACV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase 1, Aspartate alpha-decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIGZ_MOUSE
Sequence: MMVAAQVIWGSFSLLRVLWCLLPQTGYIHPDEFFQSPEVMAEDILGVQATRPWEFYPSSSCRTVVFPLLTSGSTFWLLRLWEELGLWPGLVSGYMLLVGPRFLLTALSFALDWAVYDLAPLWGADRWNALCLLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSPGVVRSPTSKKPTPGPRWHRYLLGVILAAGFFNRPTFLAFALAPLSLWGIHRASELGGIRALIQEALVLLPGAALAAVLCVATDSWYFSSLSRSTGVFLTPANFLYYNLDPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLHACLRASPQTGLSRVRGARGLLSSSKSYLLLFYFTPLLLLSAFSHQEARFLIPLLVPLVLLCSPQTQPIPWKGTLVLFNILGALIFGCLHQGGLVPGLKYLEQIVHTPDLSGTTTHYTLLFTHTYMPPQHLLHLSGLGSPVEVVDMGGAEDRVLCQALNNFSRQPACQLAGEPWPCRLFVVTPGTNRHALEKCRFPLKNETLLFPHLTLEDPPALSSLLSGAWRKHLSLHVIELETPVVTKQPKAQP
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV, Phosphatidylinositol-glycan biosynthesis class Z protein, PIG-Z.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EIF3B_BOVIN
Sequence: MQDAENVAAPEAAEQRAEPGPEQAAAEPSPGAEVARPGVQEAAGGEDAEAGPGPEGPAEPAADGEGKADATPGATPPPPEESSAQLAGEAPAEQAQDAAAEAGSEGAGGDPDGAAEDGGADEPSFSDPEDFVDDVSEEELLADVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGRTKGYIFLEYASPAHALDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGQKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNSKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNARLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 subunit 9, eIF-3-eta.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_RICTY
Sequence: MTKVITRFAPSPTGMLHVGNIRVALLNWLYAKKHNGKFILRFDDTDLERSKQKYKNDIERDLKFLNINCDQIFNQLSRVSRYNEIKNLLINKKRLYACYETTEELELKRKFRLSKGLPPIYDRASLNLTEKQIQKYIEQGRKPHYRFFLNDEPISWYDMIKGDIKYNGKALSDPIVIRADGSMTYMLCSVIDDIDYDITHIIRGEDHVSNTAIQIQMFEALNKIPPVFAHLSLIINKEEKISKRVGGFEIAYLKNEVGLEAMTITSFFSLLGSSLHIFPYKSIEKLVAQFEISSFSKSPTIYQQYDLERLNHKLLISLDYHEVKERLKEINADYIDENFWLSVRANLQKLSDIKDWWDICYQTPKIGNLNLDKEYLKQASELLPLGKITKDSWSIWTKEITNATGRKGKELFLPIRLALTGRKSGPEIAGILPLLKREEIIKRLVAIT
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.