PharMolix/UniProtQA huggingface dataset:
Protein: NDHH_PARMW
Sequence: MTQLETRTEPMVVNFGPHHPSMHGVLRLVVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMFVPYVSRMDYAAGMFYEAVVVNAPEKMADIPVPKRASYIRVLMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGQRLINNNYFRIGGVAADLPWGWLEKCRDFCDWFGPKIDEYEKLITNNPIFRRRIEGLGTIEKQDAINWSLSGPMLRASGVPWDLRKVDHYECYDDFDWQVASEKEGDCYARYRVRIEEMRQSLKILRQACDMIPGGPTENLEAKRLNEGKGSDAAGFDFQYVAKKVAPTFKIPNGELYTRLESGKGEIGVFIQGNNDVTPWRFKIRAADSNNLQILPHILKGHKVADIMAILGSIDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RRP3_YEAS7
Sequence: MSKIVKRKEKKANDELTSLAEKIRAKALENQKKLIEAEKEGGSESDSEEDATAEKKKVLKSKSKSTVSTQNENTNEDESFESFSELNLVPELIQACKNLNYSKPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRLWHDQEPYYACILAPTRELAQQIKETFDSLGSLMGVRSTCIVGGMNMMDQARDLMRKPHIIIATPGRLMDHLENTKGFSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTTYLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTYLIYLLNEFIGKTMIIFTRTKANAERLSGLCNLLEFSATALHGDLNQNQRMGALDLFKAGKRSILVATDVAARGLDIPSVDIVVNYDIPVDSKSYIHRVGRTARAGRSGKSISLVSQYDLELILRIEEVLGKKLPKESVDKNIILTLRDSVDKANGEVVMEMNRRNKEKIARGKGRRGRMMTRENMDMGER
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3, Ribosomal RNA-processing protein 3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRD_MYCA9
Sequence: MLYQILLRLFFLVSPERVHTLVFAALRAIAAFTPTRWLLNRLCAPTDPILGTEVFGVHFPAPLGLAAGFDKDGEGLKVWGPLGFGYAEVGTVTAIAQPGNPKPRLFRLPADRGLLNRMGFNNHGAAALAPRLATRTSTVPIGANIGKSKIVEPAFASSDYRVSARQVGPAADFLVVNVSSPNTPGLRDLQAIGELRKILSAVLEETTAPVLVKIAPDLSDADIDEIADLAVELGLAGIVATNTTISRAALKTTGVEDLGAGGVSGPPVAARSLEVLRRLYRRVGDRLVLISVGGIEDADDAWARIIAGASLLQGYTGFIYRGGFYAKRIHDGIAQRLRAGGFASLQDAVGSAT
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEPA_CLAM3
Sequence: MSPLASKALRPAATDPASIRNFCIIAHIDHGKSTLADRMLQMTGVVDSRSMRAQYLDRMDIERERGITIKSQAVRMPWELDGQTYALNMIDTPGHVDFSYEVSRSLAACEGAILLVDAAQGIEAQTLANLYLALENDLTIIPVLNKIDLPAADPDKYAAELASLIGGDPSDVLRVSGKTGAGVEDLLDRVSRTIPAPVGDPDAAARAMIFDSVYDAYRGVVTYVRMIDGKLSPREKISMMSTRATHEILEIGVSSPEPTPSDGLGVGEVGYLITGVKDVRQSKVGDTVTTAARPATEALPGYTEPLPMVFSGLYPIDGSDYPDLRDALDKLKLSDAALVYEPETSVALGFGFRCGFLGLLHLEIITERLSREFGLDLITTAPSVIYEVTSEDKKTVTVTNPSEFPGGKIVSVSEPVVKAAILAPKDYVGTIMELCQSRRGILLGMEYLGEDRVEVRYTMPLGEIVFDFFDNLKSKTAGYASLDYEPAGSQDSDLVKVDILLQGEQVDAFSAIVHRDKAYAYGVLMTGRLRELIPRQQFEVPIQAAIGARIIARESIRAMRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGRVEVPQEAFIAALSGDTEKKAK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPA_MYCLB
Sequence: MAELTISADDIQNAIEEYVSSFTADTFREEVGTVVDVGDSIAHVEGLPSVMTQELLEFPGGILGVALNLDEHNVGAVILGDFENIKEGQKVKRTGDVLSVPVGEAFMGRVVNPLGQPIDGRGDIEAEARRALELQAPSVVQRQSVKEPLQTGIKAIDAMTPIGRGQRQLVIGDRKTGKTAVCVDTILNQRQNWESGDPKRQVRCVYVAIGQKGTTIASVRRALEEGGAMDYTTIVAALASDSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLADHLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDATSKAQLERGARLVELLKQPQYQPMPVEEQVISLFLGTGGHLDSVPVGDVRRFETELLDHIRVAQEEILTEIRESQKLTDEAADSLTEVIKSFKKGFAATGGASVVPNEHVAALDEEKLDKESVKVHQAIPAKTSEKSKNSTPR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SCX13_TITOB
Sequence: MKTLFLIITSFILLEVEGIKNGYPRDSKGCTFECGQDAKHGDDYCDKMCKTTLKGEGGDCDFEYAECWCDNIPDTVVTWKNKEPKCKQI
What is the function of this protein?
Inhibits voltage-gated sodium channels (Nav).
What are the official names of this protein?
Sodium channel toxin To13, T NaTx8.1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_YERPS
Sequence: MKTTTMSQLRQWKQEKRKFATLTAYDASFAQLFAEQGIQVLLVGDSLGMTLQGFDSTLPVTVADVAYHTRAVRRGAPHCLLLADMPFMSYATPELAFTHAAELMRAGANMVKLEGGSWLCDTIRMLAERAVPVCGHLGLTPQSVNIFGGYKVQGREEVAANQLLQDAIALEQAGAQLLVLECVPVELAQRVTEELTIPVIGIGAGNVTDGQILVMHDALGITGGHTPKFSKNFLAHSAGDIRAAIKLYIEEVEGGIYPAEEHTFQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_OLEA2
Sequence: MAVKLRLTRMGNKKRAFYRIIAINSEARREGRPLDYIGYYNPMVDPAEVKIDTEKVQKWLERGAEPTDTVRALLKKNAQ
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NS1_I80A6
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETDENLKIAIASSPAPRYITDMSIEEISREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTEDGAIVAEISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDEDGGPPLPPKQKRYMARRVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: HERC3_HUMAN
Sequence: MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSLA
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase HERC3, HECT domain and RCC1-like domain-containing protein 3, HECT-type E3 ubiquitin transferase HERC3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
Protein: FMT_GEOMG
Sequence: MAGLSIIFMGTPDFACPTLTRLIERGEDVIAVVTQPDRPKGRGQKLVPPPVKVIAEEHGIPVLQPQKVRAPEVVAQIRELNPDLIVVVAFGQILPQSLLEIPRHGCINIHASLLPRYRGAAPINWCLINGETETGITTMQMDAGLDTGDMLVKRSISIGPDEDAQSLHDRLSLLGAETIDETLDRLQVGTLTREKQDDALTCYAPMLKKEDGLIDWKQEPQQIKNLVRGFTPWPGAYTTLDGKTLKLYKVSVATECGKPGDIMAVGKDGIIVGCGSGSLRIEELQLEGRKRLSAQDFLAGCRLEPGIRLGH
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RRF_BURMA
Sequence: MSVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKTMVAKVEKAIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQAKDAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB2_DICDI
Sequence: MSDYMMNDDSQDNPHADISQEDVWTVISAYFQEKGLVRQQLDSFDEFIQNTMQEIIDESPPITLRPESQHHPGQAVVSNNVSTFSVKFGQIYLSKPTAEIDGVSQQVTPNQARIRNLTYSAPLFVDITKTVMTGSKSKGDERRTDEVLKRIFIGKVPIMLRSQYCMLNEADDRDLTTMGECSFDQGGYFIINGSEKVLIAQEKMNNNHVYVFKKSPPSKYSYVAEIRSCQETGSRPTSTMYLKMLHNTNKGPVGIKATVPYIKQDVPVIIVFRALGFVADKDILEHICYDFKDAQMMDLMRPSLEESFVIQSQEVALDYLGKRGSTMGTREQRIKFAREVLQKEMLPHVSVAEFYETKKAFYFGYITHRLLLASLERRPLDDRDHFANKRLDLAGPLLGTLFRQLFKKLTKDVRLYLQRCIDKDKEFIASSAVKSKTITSGLKYSLATGNWGSSKSGGTKSGVAQVLNRLTFASTLSHLRRLNTPIGREGKLAKPRQLHNTHWGIVCPSETPEGQACGLVKNLAMMSYISVGSASQPILEFLEEWTTENLEEISDLSSIFSATKIFVNGMWVGIHHQPDKLLSTLRLLRRCGDVSVEVSVVRDIREKELRLYTDPGRCCRPLFVVQDNKVQIKKQHINKLINNDEYKWQDLLSEGIVEYIDAEEEETVLIAMTPEDLVPMPNEQIVHTYTHCEIHPSMILGICCSIIPFPDHNQSPRNTYQAAMGKQAMGVYITNYQLRMDTMAHVLFYPQKPLVTTRSMEYLHFRELPAGQNVCVAIACYSGYNQEDSVILNQSAIDRGLFRSMFYRAYKDEQKKQTSLMEEVFEKPERDTCAGMRHGSYEKIDDDGLVAPGVRVAGDDIIIGKTTPLPPSDDDLGPKTRRHTKRDSSTALRSSETGIVDQVILTTSGEGFKFCKVRVRSMRVPQIGDKFSSRHGQKGTCGMAYRQEDLPFTVEGIVPDIIVNPHAIPSRMTIGQLIECLLGKVSASTGDEGDATPFTDVTVEAISQALHKIGYQMTGHEVMYNGHTGRRMDAQIFIGPTYYQRLKHMVDDKIHSRSRGPVQILTRQPVEGRSRDGGLRFGEMERDCMISHGAAQFLKERLFDQSDSYRVHICDICGLIAIANLKKNSFECRRCKNKTQISQIRMPYAAKLLFQELMSMSIAPRMFTQT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  rpb2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit rpb2, RNA polymerase II subunit 2, RNA polymerase II subunit B2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THII_LISMF
Sequence: MEFDRMLIRYGELSTKGKNRKQFVTKLAQNVKRAMTDLPEVRIHGERDRMYIILNGADYQLVEERLKPIFGIQSFSPAVRVNLDVEEVKAAALALVQDAHEENGTFKVAARRSHREFPLDSNEINQEIGAYVLQNMEDLTVNVKNPDVKLTIDVRKEGVFLSCRTILGAAGLPVGSSGRAMLMLSGGIDSPVAGYLAQKRGVEIEAVHFHSPPYTSEQAKQKAVDLAAKLAKYSGQVQMHIVPFTEIQEVIKQQIPESVIMTVTRRMMLRITDELRRRRNGLAIVNGESLGQVASQTLESMLAINAVTATPIIRPVVSMDKNEIIQIAQKIDTYNLSVQPFEDCCTIFTPPSPKTKPKLDKIEHYESFTDFEALIAKALDNIETISVNVAETAQVKDEFADLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_RICCN
Sequence: MSDTEDNKNKQTTRRDFMVLTASSVAAIGAVCTLWPLVDSLNPSADVLALSSIEVDLSNIAVGQTVTVKWQGKPVFITNRTPDKIAEARAVKMSELIDPEADQARVKAGHDNWLVTIGICTHLGCVPLANQGEYDGWFCPCHGSQYDSSGRVRRGPAPLNLAVPPYTFISDKKIRIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RNH_PECAS
Sequence: MRKQVEIFTDGSCLGNPGPGGYGAVLRYKQHEKALSAGYRLTTNNRMELMAAIAALETLTTDCDIVLSTDSQYVRQGITSWIHNWKKRSWKTADKKPVKNVDLWKRLDTAIQRHSVRWEWVKGHAGHPENERCDELARAAASAPTLDDTGYQAE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSBP1_BOVIN
Sequence: MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDSENKIPATQKS
What is the function of this protein?
Negative regulator of the heat shock response.  Negatively affects HSF1 DNA-binding activity.  May have a role in the suppression of the activation of the stress response during the aging process (By similarity).
What are the official names of this protein?
Heat shock factor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the HSBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAIC_PARMW
Sequence: MQFPPASGSTQMQVQKLPTGIEGFDDVCQGGLPIGRSTLISGTSGTGKTVFSLHFLHNGIKHFDEPGIFVTFEESPLDILRNAASFGWNLQEMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIRKYKAKRVAIDSITAVFQQYDAVFVVRREIFRLIARLKEIGVTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEFPFTMGTHGISIFPLGAMRLTQRSSNVRVSSGVPRLDEMCGGGFFKDSIILATGATGTGKTLLVSKFIEDACRNKERAILFAYEESRAQLLRNGTSWGIDFEQMEQDGLLKIICAYPESTGLEDHLQIIKTDIGQFKPSRMAIDSLSALARGVSHNAFRQFVIGVTGYAKQEEIAGFFTNTSEEFMGSHSITDSHISTITDTILMLQYVEIRGEMARALNVFKMRGSWHDKGIREFVITGNGPQIKDSFSNFERIISGVPHRVTTDERSELSRIARGVSSED
What is the function of this protein?
Has a weak, temperature-independent ATPase activity; ATPase activity defines the circadian period.  The phosphorylation state of KaiC modulates its ATPase activity and effects KaiB binding.
What are the official names of this protein?
Circadian clock oscillator protein KaiC.
What is the protein family that this protein belongs to?
Belongs to the KaiC family.
Protein: ACPS_RUEST
Sequence: MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACSKALGTGLRMGIAWKDMSVSNLSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPWAQAVVMIEARPILPDVQTAQTT
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX3_GAZSA
Sequence: MTHQTHACHMVNPSPWPLTGALSGLLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDVIRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LGT_MYCLE
Sequence: MTRMLPGYFPSPPRGVWHLGPLPIRAYALLIILGIVAALVVGGRCWEARGGERDVTYDIALWAVPFGLVGGRLYHLATDWRTYFGQNGAGLGAALRIWDGGLGIWGAVALGCVGAWLGCRRHRIPLPAFGDALAPGIILAQAIGRLGNYFNQELYGRETTMPWGLEVFYRRDPAGYMDPHSLDGVSTGQLAFVVQPTFLYELIWNVLVFFALIYVDRWFTLGHGRLFATYVAAYCIGRFCVELLRDDAATHIAGIRINSFTSTFVFIGAVVYIILAPKGREEPENLCRAEYVAREIPEPESATERATVASTYATTTAVPVSADEEFAETN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1330_BURP0
Sequence: MIIVLSPAKSLDYETPPHVSHHTQPQFADDAAALIDELRRLSPQQIATLMSISDPLARLNFQRYADWSRASTPANAKQAVLAFNGDVYEGLDARSLSPDDLDYAQRHVRVLSGLYGLLRPLDLLQPYRLEMGTRFSNARGKDLYAFWGERITHALNAELKTRVGASRVLVNCASAEYFKSVKPKLLDARVVTPVFEDWKDGRYKIISFHAKRARGLMARYVVEGRIDSPDALKDFASEGYAFDASASNDDTYVFRRRAGA
What are the official names of this protein?
UPF0246 protein BURPS1106A_1330.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: WECA_MYCTO
Sequence: MQYGLEVSSDVAGVAGGLLALSYRGAGVPLRELALVGLTAAIITYFATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQLPALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASVLVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLDGLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLPHNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPFLLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLIIYLWVGIVAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGDDYYDPDLD
What is the function of this protein?
Involved in the biosynthesis of the disaccharide D-N-acetylglucosamine-L-rhamnose which plays an important role in the mycobacterial cell wall as a linker connecting arabinogalactan and peptidoglycan via a phosphodiester linkage.  Catalyzes the transfer of the N-acetylglucosamine-1-phosphate (GlcNAc-1P) moiety from UDP-GlcNAc onto the carrier lipid decaprenyl phosphate (C50-P), yielding GlcNAc-pyrophosphoryl-decaprenyl (GlcNAc-PP-C50) (By similarity).
What are the official names of this protein?
Decaprenyl-phosphate N-acetylglucosaminephosphotransferase, Decaprenyl-phosphate GlcNAc-1-phosphate transferase, Decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase, UDP-GlcNAc:decaprenyl-phosphate GlcNAc-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. WecA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.