PharMolix/UniProtQA huggingface dataset:
Protein: HEM6_RICCN
Sequence: MNIENKEITSSWFTNLRDLLCKEFEKIEEEYAQTKGLKPAKFVRSSWQRNGGGGGVMSLMKGAVFEKVGVNISTVFGKISPEFRNEIPGAELDGKFFATGISLVAHLKSPLIPAMHFNTRYIETSKSWFGGGGDLTPFYPEKNETVKFHAAFKEACDKYDSSYYPKFKKQCDEYFYLKHRKEPRGVGGIFYDYLNNGNFEQDFAFTQDVGKALLSVYPEIVRSKLFLPWTAEQKEYQLIRRGRYVEFNLLYDRGTKFGLMTDGNVEAILMSLPPEVKFN
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF176_ARATH
Sequence: MAKATSSLVVPIIFLVIFALVEQNTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPDDKAIPDVKLFKNVKEQILS
What are the official names of this protein?
Defensin-like protein 176, Low-molecular-weight cysteine-rich protein 65, Protein LCR65.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPA_SALEP
Sequence: MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEIHSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEKSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: DNLI_MYCBP
Sequence: MLLHDVAITSMDVAATSSRLTKVARIAALLHRAAPDTQLVTIIVSWLSGELPQRHIGVGWAALRSLPPPAPQPALTVTGVDATLSKIGTLSGKGSQAQRAALVAELFSAATEAEQTFLLRLLGGELRQGAKGGIMADAVAQAAGLPAATVQRAAMLGGDLAAAAAAGLSGAALDTFTLRVGRPIGPMLAQTATSVHDALERHGGTTIFEAKLDGARVQIHRANDQVRIYTRSLDDVTARLPEVVEATLALPVRDLVADGEAIALCPDNRPQRFQVTASRFGRSVDVAAARATQPLSVFFFDILHRDGTDLLEAPTTERLAALDALVPARHRVDRLITSDPTDAANFLDATLAAGHEGVMAKAPAARYLAGRRGAGWLKVKPVHTLDLVVLAVEWGSGRRRGKLSNIHLGARDPATGGFVMVGKTFKGMTDAMLDWQTTRFHEIAVGPTDGYVVQLRPEQVVEVALDGVQRSSRYPGGLALRFARVVRYRADKDPAEADTIDAVRALY
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: TIG_BORBR
Sequence: MQPVVETLSGLERRVDLAVSVAEVEKEVQAQLKRVGRTAKVAGFRPGKAPLAMLERSHGPGIRYDVINSLVGRAFEQAVDGAKLRVAGSPTLTPKTEGVADDTLAFTATFEVYPEVTVPDLSALAVTRYDTPVTDAEVNQTLDVLRKQRAKFETREGRASQDGDRVVLDFAGTIDGVPFEGGKAEDFPFVLGQGRMLPEFEEAALGLKAGESKVFPLKFPDDYQGKEVAGKTAEFTITVKEVAEGVLPEVDAEFAKSLGQAEGDVEKLKADIRTNIEREVKARLQGRTKGSVMDALVEAGKFDVPKALVDSDVEGRIAAAREELKQRGVPNADSVPMPAEVFSTESERRVRLGLLVSELVKQAQLQAKPEQVRARIEEFAQNYEQPAQVVSYYLADRQRRAEIEAIVLEDNVVAHVLENAKVADEKVPFDQLMGMA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TRAP_STAA8
Sequence: MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
What is the function of this protein?
Signal transduction protein, which is a major regulator of staphylococcal pathogenesis.  Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors.  Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation.
What are the official names of this protein?
Signal transduction protein TRAP, Target of RNAIII-activating protein.
What is the protein family that this protein belongs to?
Belongs to the TRAP family.
What are the subcellular locations of this protein?
Membrane. Note=Membrane-associated.
Protein: TNAA_HISS2
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYRDEAILKAGMNLFLLDSEDIFIDLLTDSGTGAVTQDMQAAMLRGDEAYSGSRSYYALANAVKEIFGYEYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRNKMVVFSNYFFDTTQGHSQLNGATVRNVYIKEAFDTDVDHDFKGNFDLEKLEQGILEVGANNVPYIVCTITCNSAGGQPVSLANMKAMYQIARKYDIPVIMDSARFAENAYFIQQREAEYKDWTIEQITYESYKYADALAMSAKKDAMVPIGGLLCFKDNSMEDVYNECRTLCVVQEGFPTYGGLEGGAMERLAVGLRDGMRQDWLAYRISQIEYLVQGLEKIGVVCQQPGGHAAFVDAGKLLPHIPAEQFPAQALACELYKVAGIRSVEIGSLLLGRDPKTGQQLPCPAELLRLTIPRATYTQTHMDFIIEAFKQVKENAKNIKGLDFTYEPKVLRHFTARLKEI
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RAPA_VIBCM
Sequence: MSFALGQRWISDTESDLGLGTVVALDARTVTLMFAASEENRVYARSDAPVTRVIFNVGDVVDSQQGWSLQVEQVVEDQGVYTYLGTRVDTEESGVALREIFLSNQIRFNKPQDKLFAGQIDRMDNFVLRYRALTNQYQQHKSPMRGLCGMRAGLIPHQLYIAHEVGRRHAPRVLLADEVGLGKTIEAGMIIHQQVLTGRAERILIVVPETLQHQWLVEMMRRFNLHFSIFDEERCVEAFSEADNPFETQQYVLCSLDFLRKSRQRFEQALEAEWDLLVVDEAHHLEWHPEKPSREYQVIEALAEQTPGVLLLTATPEQLGRESHFARLRLLDADRFYDYEAFVKEEEQYAPVADAVTALFSGEKLSDEAKNKITELLSEQDVEPLFKALESHASEDEIALARQELIDNLMDRHGTGRVLFRNTRAAIKGFPVRNVHLLPLEIPSQYTTSMRVAGMLGGKLTPEARAMKMLYPEEIFQEFEGEESSWWQFDSRVNWLLEKVKAKRSEKILVIASRASTALQLEQALREREGIRATVFHEGMSIIERDKAAAYFAQEEGGAQVLICSEIGSEGRNFQFANQLVMFDLPFNPDLLEQRIGRLDRIGQKRDIDVYVPYLTETSQAILARWFQEGLNAFAETCPTGRAVYDAFAERLIPILAAGGGEELEVIIEESAKLNKTLKSQLEVGRDRLLEMHSNGGEKAQQIAEQIAKTDGDTNLVTFALSLFDAIGLHQEDRGENALVVTPAEHMMVPSYPGLPYEGATITFDRDTALSREDMHFISWEHPMVQGGIDLLMSEGVGTCAVSLLKNKALPVGTILLELVYVVDAQAPKRSGISRFLPVSPIRILMDARGNDLSSQVEFESFNRQLSPVNRHLASKLVSSVQHDVHRLITASETAVEPRVSAIREQAQRDMQQSLNSELERLLALKAVNPNIRDEEIEVLDQQIKELTGYIAQAQYQLDSLRLIVVAHN
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: CCD17_MOUSE
Sequence: MADYSGESGLLSCESCDMVFRSWALLATHTKRFCIGRLTPEVTLKSQPSVAIKRGTKIMAQEKSRDQEASTSALKRLTEETAGSPGERLRVLQGTRARRMAETEAQSRALERRGEELKRRLHSVAGPKGGLPRPFDLERELRELKEEANRTRGALQTLGAHFQALQLQPRKLQDTHRAVEFCYLPLRFNPETLAAEIRILREAYVHGGGRDPEVLDKILQLQVEASALELQRSQNRKEKLSAASEEVLTVEAENRLLEAEILALQKQKVLSLSPWGSRDLPGHLSRCDNSLLPPLVAPPIPQLTSSTKAQNFHGTSKTILNGTMTRKMGLDLHFLLPASDVLGPAPYDPGAGLVIFYDFLRGLDTSWIWVQLMTSLARNGQDTGGTTALPPALCLPQPSAPGPMGNCAILASKQPVPRLPPSPLVSLICELQAWHGVTWAPQPKAWASLLLFDQDLRVLRGRWRLPLRVYPNTSLSLAQRNEIPQAGQAELFLRLVNARDTDAQTLAEINPANAHEYQYPPMVSSSSVESSFFTHSSAFADPPPPTEEAFVSVKDKNEHLSPHQF
What are the official names of this protein?
Coiled-coil domain-containing protein 17.
Protein: LIPB_MANSM
Sequence: MEQKLIIRQLGIRDYQKTWHEMQEFTDNRTDKSADEIWLVQHPSVFTQGQAGKAEHLLRSTAIPVVQSDRGGQITYHGIGQQIMYVLIDIKRLKTQGRDISVRQLVSALEQSVINTLADYGIESYAKADAPGVYIDGKKICSLGLRIRRGCSFHGLALNINMDLEPFHSINPCGYAGLEMAQLADFVSPQEADCGKVSPKLVEHFVTILGYNKQQIFNIKE
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUTJ_BACSU
Sequence: MKKLVLIGGGYGNMRVLHRLLPNQLPDDVSITLIDRNPYHCLKTEYYALAAGTISDHHIRVSFPEHPRLDVQYGDITSIDIVQKQVLFQDREPISYDDAIIGLGCEDKYHNVPGAPEFTYSIQTIDQSRETYQKLNNLSANATVAIVGAGLSGVELASELRESRDDLNIILFDRGNLILSSFPERLSKYVQKWFEEHGVRIINRANITKVEEGVVYNHDDPISADAIVWTAGIQPNKVVRDLDVEKDAQGRIVLTPHHNLPGDEHLYVVGDCASLPHAPSAQLAEAQAEQIVQILQKRWNGEALPESMPQFKLKGVLGSLGKKAGFGLVADRPLIGRVPRMLKSGLLWMYKHHNG
What are the official names of this protein?
NADH dehydrogenase-like protein YutJ.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: MSH3_BOTFB
Sequence: MGKPNSTPAKTQKSISSFFAPKSSQKPQDSSSPPASKAPGNLDDADSNEGTNEDAKITGNRLKRVLEEDENGGNTGAKERPSKRAKSVEVEEEDNESYALPAADSRKTSSSLTRGKSKPSLRTNKYMFSGSSQRATESLIEEEPEDELEKARKVELHKKFVKKLGHPDSLRRIIHEDDAALEVGDEEGEEDEEAPAPVKTKKKGAKTGKLTPMELQVIDIKRKHMDTLLIVEVGYKFKFFGEDARTAAKVLSIVCIPGKFRFDEHPSESHLNYFASASIPVHRLPVHAKRLVAAGYKIGIVRQTETAALKKAGDNRNAPFVRKLTNVYTKGTYIDDIDGLDTTDAPSGGAPATGYLLCITETKAKGWGTDEKVEVGILAVQPATGDVIYDNFEDGFMRGELETRLLHIAPCELLIVGELTKATDKLVQHLSGSSTNVFGDRIRVERVGKSKTMAAESYSRVAQFYADKLKAHQSSNNAREQELLEKVLKLTEPVTICLSAMITHMTEYGLEHVFDLTKYFQSFSARSHMLLNGNTLTSLEIYTNQTDYTQKGSLFWTLDKTQTKFGQRLLRKWVGRPLLDKQRLEERVAAVEELKDNANTPKVDKLNATLREVRSDLERSLLRIYYGKCTRPELLTVLQTMQRIANEFAHVKTPSDAGFESIALNEAVASLPAIGEIVISFLDKINAQAARNDDKYAFFLEHYETEAIGDHKCGIGAVEQDLEAHRMVAATKLSKKTPVTYVTIAGIEYLIEVPNTDLKNVPASWAKISGTKKMSRFHTPEVIKFLRERDQHKESLSSACDAAFSTFLSEISTHYALIRDTISHLATLDCLLSLATVASLPGYCKPTFTSSTEISVIGGRHPMVEQLLPSAYIPNDTSLSTSPDHTRALLLTGPNMGGKSSYVRQVALISILAQIGSYVPAESARLGLLDGIYTRMGAYDSLFTAQSTFMVELSETASILKSAGPRSLVILDELGRGTSTHDGVAIAEAVLDWVVRETKCLCLFITHYQTLASVARGFEKGKELRNVHMKFTAERNGRRVSNADADKDNEDFDEEITFLYEVGEGVAHRSYGLNVARLARVPKSVLDTAASKSRELETQVKQKKLLGLSNMISNVLENGTDQLDQLIIGMEQL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  Msh3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein msh3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATL37_ARATH
Sequence: MTIFTRDFSHRILACVLLPLFLFQCLPYVTCQQGSESAGRNGKSKESSIIGIVLLSLFLLLLVVYCLNYGCCIEENETGGHEVLHSRVRRGIDKDVIESFPAFLYSEVKAFKIGNGGVECAICLCEFEDEEPLRWMPPCSHTFHANCIDEWLSSRSTCPVCRANLSLKSGDSFPHPSMDVETGNAQRGVQESPDERSLTGSSVTCNNNANYTTPRSRSTGLLSSWHVPELFLPRSHSTGHSLVQPCQNIDRFTLQLPEEVQRQLVSLNLIKRSHIALPRARSSRQGYRSGSVGNERTGFSQGRQTLRRAISTSLSFSFQPAPVRSTLDRDNLMRETSQANDKDFGERSFQRLMPEKN
What are the official names of this protein?
Putative RING-H2 finger protein ATL37, RING-type E3 ubiquitin transferase ATL37.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOH_SALDC
Sequence: MSWITPDLIEILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLSFAIVPVSPNWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTVSYEVFLGLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUB2_ARATH
Sequence: MAEVKDQLEIKFRLNDGSDIGPKLFPDATTVATLKETVVAQWPRDKENGPKTVKDVKLISAGRILENNKTVGDCRSPVGNFSGAVTTMHVIIQHQVTEKEKKKKKPKGDLKQNKCVCLCFGARC
What is the function of this protein?
May serve as docking site to facilitate the association of other proteins to the plasma membrane.
What are the official names of this protein?
Membrane-anchored ubiquitin-fold protein 2, AtMUB2, Membrane-anchored ub-fold protein 2, NTGP5.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL19_METFK
Sequence: MADIIKQLEQEEIARLGKTIPSFAPGDTVVVGVNVVEGTRKRVQAYEGVVIAIRNRGLNSSFIVRKISSGEGVERTFQTYSPLIASIEVKRRGDVRRSKLYYLRERSGKSARIKEKLQLRAPKETSSAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DPYS_HUMAN
Sequence: MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP
What is the function of this protein?
Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines.  Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
What are the official names of this protein?
Dihydropyrimidinase, DHP, DHPase, Dihydropyrimidine amidohydrolase, Hydantoinase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: COBD_PHOLL
Sequence: MTLAAWFAAFLLDSWLGDPPHWPHPVRWIGKLISLVQRAVRRCCHSERALKVGGAGLWIVVVGLTWLVSWGCLWLMNAIHPWVGWLVEVWMIYTLLAGRCLSDTALEVHGVLQQGLLDESRQQLSWIVGRDTSQLDAPQITRAVVETVAENSVDGVIAPLFFLMIGGAPLAMAYKAINTLDSMVGYKTQEYHAIGYVSARMDDLANWLPARLSWLLLSAAAWFIRLDFRQALRIGWRDRYQHTSPNCGWSEATVAGALGIRLGGPSCYFGERVEKPWMGDERRKIALTDIPLSIYLMMIASQLALLLFALLRLLLVGMA
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSIX_STRAW
Sequence: MTKTTMAVPGALLAAIALLSAAPAQAAAHRVTPGNWLYVTVTTGDARSSHISRLLTCDPPHGHAHAARACEELAAADGDITRIPPKRTFCPMIYAPVTADAHGEWNGRHVEYRHAFGNACGLEGETGAVFALSEQASDGPTPGLRS
What are the official names of this protein?
Putative serine protease inhibitor SAV_2156.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSA_CAUVC
Sequence: MDQPKAVAPNAVVEIKTPTGAPVRIGNGEKLSIIAGPCQMESRQHALETAHALKEMADRLGVGLIYKTSYDKANRTSANAQRGIGLKDSLAIFQEIREVTGLPTLTDVHETSHCSIVAEAVDVIQIPAFLCRQTDLLVAAASTGRAINIKKGQFLAPWDMKNVIAKVTGAGNPNVMACERGASFGYNTLVSDMRALPIMKEIGCPVVFDATHSVQQPGGQGTSSGGQREFVPTLARAAVAVGVACVFIETHPDPDNAPSDGPNMVPVKEFEALVANLLRYDALTKAA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_FRAT1
Sequence: MANDRVPMTPAGEQALRAELDKLKKIERPAIIEAIAEARDHGDLKENAEYHAARERQGIIEGRIKDIESKLSNAQVIDVTKIQANGMVIFGATVTIMNVDTEEETTYKIVGEDEADIDNQKISVVAPLARALIKKEEGDEITLDTPKGKVTYEIVAVEYK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: POT12_ARATH
Sequence: MEEIEEGSSNNSIRRVGTGSSDRRWVDGSEVDSETPLFSEIRDRDYSFGNLRRRLMKKPKRADSLDVEAMEIAGSHGHNLKDLSLLTTLGIAFQTLGVVYGDMGTSPLYVFSDVFSKVPIRSEVDVLGALSLVIYTIAVIPLAKYVFVVLKANDNGEGGTFALYSLICRYAKVNKLPNQQPADEQISSFRLKLPTPELERALGIKEALETKGYLKTLLLLLVLMGTSMIIGDGILTPAMSVMSAMSGLQGEVKGFGTNALVMSSIVILVALFSIQRFGTGKVGFLFAPVLALWFFSLGAIGIYNLLKYDFTVIRALNPFYIVLFFNKNSKQAWSALGGCVLCITGAEAMFADLGHFSVRSIQMAFTCVVFPCLLLAYMGQAAYLTKHPEASARIFYDSVPKSLFWPVFVIATLAAMIASQAMISATFSCVKQAMALGCFPRLKIIHTSKKRIGQIYIPVINWFLMIMCILVVSIFRSTTHIANAYGIAEVGVMMVSTVLVTLVMLLIWQTNIFLALCFPLIFGSVETIYLLAVLTKILEGGWVPLVFATFFLTVMYIWNYGSVLKYQSEVRERISMDFMRELGSTLGTIRIPGIGLLYNELVQGIPSIFGQFLLTLPAIHSTIIFVCIKYVPVPVVPQEERFLFRRVCPKDYHMFRCIARYGYKDVRKEDSRVFEQLLIESLEKFLRCEALEDALESTLNDFDPDRVSVASDTYTDDLMAPLIHRAKRSEPEQELDSEVLPSSSVGSSMEEDPALEYELAALREATDSGLTYLLAHGDVRAKKNSIFVKKLVINYFYAFLRRNCRAGAANLTVPHMNILQAGMTYMV
What is the function of this protein?
Putative potassium transporter.
What are the official names of this protein?
Putative potassium transporter 12, AtPOT12.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VP26A_DANRE
Sequence: MSFLGGLFGPVCEIDVILNDAESRKTAELKTEEGKLEKHYLFYDGESVSGKVNINVKQTSKRLEHQGIRIEFVGQIELFSDKSNTHEFVNLVKELALPGELTQNRSYDFEFMQVEKPYESYVGANVRLRYFLKVTIVRRLSDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEMTGIGPSTTTETETVAKYEIMDGAPVKGESIPIRLFLAGYDLTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIVLWRKAPEKMRKRNFHQRYESPEPRPSLSAEQPEM
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26A, Vesicle protein sorting 26A.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome. Note=Localizes to tubular profiles adjacent to endosomes.
Protein: RDR1_ARATH
Sequence: MGKTIQVFGFPNGVSAEEVKKFLERLTGSGTVYAIKVRQPKKGGPRVYAIVQFTSERHTRLIITAAAERLYYGRSYLKAFEVEQDIVPKPRASLHTISGLKMFFGCQVSTKKFLTLWSAQDVCVSFGIGMRKLHFSFSWYQKDYRLELSYENIWQIDLHSPQGRSSKFLVIQVIGAPKIFEKEDQPINLLFGIMDFYSDGSDEQWIRTTDFTSSSCIGQSTAFCLELPVHLNVPDFRENFANYAEHRASSFLIESGSSYSSNANTLVPVVDPPPGFSLPFEILFKLNTLVQNACLSGPALDLDFYRLLNQKKYDRALIDHCLEKLFHLGECCYEPAHWLRDEYKKWISKGKLPLSPTISLDDGLVYMYRVQVTPARVYFSGPEVNVSNRVLRHYSKYINNFLRVSFVDEDLEKVRSMDLSPRSSTQRRTKLYDRIYSVLRDGIVIGDKKFEFLAFSSSQLRENSAWMFAPIDRITAAHIRAWMGDFDHIRNVAKYAARLGQSFSSSRETLNVRSDEIEVIPDVEIISLGTRYVFSDGIGKISAEFARKVARKCGLTEFSPSAFQIRYGGYKGVVAVDPNSSKKLSLRKSMSKFESENTKLDVLAWSKYQPCYMNRQLITLLSTLGVTDSVFEKKQREVVDRLDAILTHPLEAHEALGLMAPGENTNILKALILCGYKPDAEPFLSMMLQNFRASKLLELRTKTRIFISGGRSMMGCLDETRTLEYGQVVVQYSDPMRPGRRFIITGPVVVAKNPCLHPGDVRVLQAVNVPALNHMVDCVVFPQKGLRPHPNECSGSDLDGDIYFVCWDQELVPPRTSEPMDYTPEPTQILDHDVTIEEVEEYFANYIVNDSLGIIANAHTAFADKEPLKAFSDPCIELAKKFSTAVDFPKTGVAAVIPQHLYVKEYPDFMEKPDKPTYESKNVIGKLFREVKERAPPLISIKSFTLDVASKSYDKDMEVDGFEEYVDEAFYQKANYDFKLGNLMDYYGIKTEAEILSGGIMRMSKSFTKRRDAESIGRAVRALRKETLSLFNASEEEENESAKASAWYHVTYHSSYWGLYNEGLNRDHFLSFAWCVYDKLVRIKKTNLGRRQRQETLERLDHVLRFG
What is the function of this protein?
RNA-dependent direct polymerase involved in antiviral silencing.  Required for the production of some small RNAs (mainly 21 and some 22 nucleotides) derived from the crucifer-infecting tobamovirus (TMV-cg).  Required for turnip mosaic virus (TuMV) silencing and accumulation of viral siRNAs.  Involved in cucumber mosaic virus (CMV) silencing.  Required for the biogenesis of viral secondary siRNAs, process that follows the production of primary siRNAs derived from viral RNA replication.  Specifically targets the positive-strand of the 3 RNA genomes of CMV and preferentially amplifies the 5'-terminal siRNAs of each viral genomic RNA.  Not involved in the production of siRNAs derived from a single-stranded 336-nucleotide satellite RNA of CMV.
What are the official names of this protein?
RNA-dependent RNA polymerase 1, AtRDRP1, RNA-directed RNA polymerase 1.
What is the protein family that this protein belongs to?
Belongs to the RdRP family.