PharMolix/UniProtQA huggingface dataset:
Protein: LUXS_DEIRA
Sequence: MPDMANVESFDLDHTKVKAPYVRLAGVKTTPKGDQISKYDLRFLQPNQGAIDPAAIHTLEHLLAGYMRDHLEGVVDVSPMGCRTGMYMAVIGEPDEQGVMKAFEAALKDTAGHDQPIPGVSELECGNYRDHDLAAARQHARDVLDQGLKVQETILLER
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: PP2C2_YEAST
Sequence: MGQILSNPVIDKESHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTDVKLLQDPVMKEDHSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLKEGEDVAQWSDRMKSKAHRTSVRSFADKRRRVFSYYDFSKCNDEQVFAITTKKPQDKFTRDHEAAVASVTAADNDDPMDIDDTDADTDAENLDPSSQSKSKTSGPIDLASLEALLGATGGVKTDSNGNKVTYTLPQSALAQLLQTMGHDPASSHPENDSNTDHKAGRSHLQ
What is the function of this protein?
Responsible, together with PTC3, for the dephosphorylation of the cyclin-dependent protein kinase CDC28.
What are the official names of this protein?
Protein phosphatase 2C homolog 2, PP2C-2.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: DNAK_STRAG
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVEEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIQSNSGLTDEEIDKMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKKAQESGNLDDMKAKLEALNEKAQALAVKLYEQAAAAQQAAQGAEGAQSADSSSKGDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL34_MAGMM
Sequence: MKRTFQPSKIRRKRTHGFRARMATKNGRKVLAARRRKGRKALIP
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL20_ERWT9
Sequence: MARVKRGVVARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARTNGISYSRFINGLKKASIEIDRKILADIAVFDKAVFAALVEKAKTALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LSPA_PELTS
Sequence: MFLFIIIAVVLLVDQATKAAVQMLMCQGESIPVVPPAFYLTYIMNPGAAFGLLPHKKMLFVTVTVIIIAGVLVGYFKIRPRKPVLDYGLGLVAGGALGNLADRLRYGLVVDFLDFRIWPVFNLADTAIVTGAFLLAWALLNDSDKSSKKERK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCSP_MOUSE
Sequence: MSDPSKTNQCPPPCCPPKPCCPPKPCCPQKPPCCPKSPCCPPKSPCCPPKPCPCPPPCPCPCPATCPCPLKPPCCPQKCSCCPKKCTCCPQPPPCCAQPTCCSSENKTESDSDTSGQTLEKGSQSPQSPPGAQGNWNQKKSNK
What is the function of this protein?
Involved in sperm motility.  Its absence is associated with genetic background dependent male infertility.  Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida.
What are the official names of this protein?
Sperm mitochondrial-associated cysteine-rich protein.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Note=Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis.
Protein: YKV5_SCHPO
Sequence: MKLFLYHFTFIVYYFIISFSYAFSIKQEIIVSSHNASSILNTTAFWFVEFTESKYDKEEFSVIWNEVSMEFPDIRRAKVFCDLDLEFCAQQEIYDHPKVVVLKNGMWMRHVLEKNQITTKSARQFVKSHLGNCDLEQAENETDCFSDDGEYNSDSSSTDPAFELKEDQSWKHSSILRPLETLNFKRFLFGNEIMSKTRAFVMFVSLKHCEDCFHWEAVWSSITRNTDERLKMAQVNCDEEKEMCNHFHIKKFPTFRVFQGFDSIQYNGPLKYQQLLSYSNQVASYQAIKIEEGDIESIENSHPVFFLVLYDFATTSEDFSIIERLKLQLAGVAPLYICNSKALANKYGAQSQPSIIAVRNGMPIVYQAITPREFRDYKRITEWINIVSSPFITELTPTKCHSLLNRKLTVLTLLQPDSEQFFSSQEELLRLGKRWFRFQMQRQRNDIVWSRIKKYSAIAEAKKKGFARKVKRIKYSKISHPTYTESVSFLWLDSSLWLDWIVENLDHTVYVDSITPPVFVIDHSKGVIYVSDRNGNSLTLEEDSLFSTLRIILEHPNSSRLQKLRAPGLCPNGSPNYRNRYKLIVFNLLIALLILSILTIISASRLSRRRRQLLNKQPVFGFYHSLVIAKSD
What is the function of this protein?
Acts as a membrane-bound chaperone in endoplasmic reticulum quality control.  Probably facilitates presentation of substrate to membrane-bound components of the degradation machinery (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein C959.05c, Putative protein disulfide isomerase C959.05c.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: DYR_STAHA
Sequence: MWSFLKISLIVAMDKKRVIGKDNDIPWRISSDWEYVKNTTKGHAIILGRKNLQSIGRALPDRRNIILTRDKNFNFKDCEIAHSIEAAFKLCENEEEVFIFGGEQIYVMFLPYVEKMYVTKIHHEFEGDTFFPVVNFDDWKEVSVEKGIKDEKNPYDYYFHIYERIR
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: IAPP_CANLF
Sequence: MCLLKLPVVLIILSVALNHLKATPIKSHQMEKRKCNTATCATQRLANFLVRTSNNLGAILSPTNVGSNTYGKRNTIEILNRGPLNYLPL
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARC_GEOOG
Sequence: MGPGLGNGPDEFRARRERDVTALLSQISYLEEEIGLLRRKVAESPRQLRLLEERLAEAEGRAAFLSERNDKLAGTLRDARDQLVTLKEEVDRLGQPPSGYGVFLTRHDDGTVDVFTGGRKLRVSVSPAVEVDVLQHGQEVMLNEAMNVVEACGFERAGDVVMLKELLEPVEGEAPRALVIGHTDEERVVHLAESLTDQPLRSGDSLLLETRSGYVYERIPKSEVEELVLEEVPDIDYGDIGGLSRQIEQIRDAVELPFLHADLFREYELRPPKGILLYGPPGCGKTLIAKAVANSLAKKVSAVKGEGQAKSYFLNIKGPELLNKYVGETERHIRLVFQRAREKAGEGTPVIVFFDEMDSIFRTRGSGVSSDVESTIVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAARDIFSKYLTTTLPLHPDDLAEHGNSREATVGGMIQRTVERMYTESEENRFLEVTYANGDKEVLYFKDFNSGAMLQNIVDRAKKMAIKERLETGAGGLRVGHLMQACVDEFKENEDLPNTTNPDDWARISGKKGERIVYIRTLISGKGAESGRAIDTATNTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: CYB_HYDIN
Sequence: MTNMRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGVLLLILFLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILVLILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFLIILVLMPIISSIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UPP_HAES1
Sequence: MKIVEVKHPLVKHKLGLMRVADITTKDFRELATEVGSLLTYEATSDLETEKVIIDGWCGAVEIDRIKGKKVTVVPILRAGLGMMDGVLEHVPSARISVVGMYRDEETLEPVPYFQKLASDLDERLAIVVDPMLATGGSMIATINLLKAKGCQHIKVLVLVAAPEGIKALEAVHPDVELYTASIDSHLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PSBL_BARVE
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TILS_VIBC3
Sequence: MDDLYLHFVQQLARYPFRKILLALSGGVDSQVLLALLARGRDEFGWDVTAVHVHHGLSPNADQWAQHCQRCCREVGMACQIEYVQLDVASGESIEKLAREARYRVLAPHVNAQTLLLLGQHADDQLETFLLALKRGSGPKGLAAMAAYAPFAEGHLLRPLLTVSRQHIEAYAKQHKLTWVIDESNADIRYERNFLRHQVTPVLTERWPSIRQAVQRSAELCAEQEALLQEFLAEALKKAITAEGGLSIAVLAEGSEGMRRQLIRAWFAHHRLPMPSRQHTERIWCEVALASEDANPKLKLNHIEVRRFQHCLYLVPPEKDLSGWRSALVPEQRLPLPQGLGHLQLTSKAGGNIKLPDDPSQLWVSFEPQGLEACPVGRVGSRKLKKLFQEYGVPSWRRRQTPILMYQNRVVCVADLFVDRDWSGQDCELVWFKSHDSVPK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAT_BACVZ
Sequence: MSLAPHGGTLINRVNEQYDLTSVQKEIELDLISFADLELIGIGGYSPIEGFFTEKDYVSVVENMRLASGVVWSLPITLPVDSEKAAELAVGDTVKLTYGGETYGVVDIEDIYTPDKQKEAVHVYKTDDAAHPGVKKLFSRGDTYVGGPITLVKKASKQFPEFTFEPADTRRSFEQKGWKTIVGFQTRNPVHRAHEYIQKTALETVDGLFLNPLVGETKSDDIPADVRMESYQVLLDHYYPKDRVFLGVFLAAMRYAGPREAIFHALVRKNYGCTHFIVGRDHAGVGDYYGTYEAQELFDQFTADELGITPMKFEHSFFCQKCGNMGTAKTCPHDKEDHVILSGTKVREMLRSGVMPPAEFSRPEVVEVLIKGLKTKEEAGVS
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: ZAPB_SALEP
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSAQHQREELERENNSLKEQQSGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: TAF4_CAEEL
Sequence: MSLPRFRLVQGKAIGERSTPGVSTPEPAPPQIKQEVDYQDAHQMAPEPVEAPQAQNHQMQPPRQPIQQQMQHFQSPSPMAPQGPPGTPQNSAAAAAAASDDKNVTKCVRFLKTLINLSNNDDPEMPDKAARVKELIRGVIYLETTAEEFTRNLQQVLKSQAQPHLLPFLQNTLPALRNAVRNGTASVEGVNPPPGYVFNNGRTPGPPQPPPPQQQSQQQPPLEMRQIPNPNQIPPQMVQGGPHMVSVGARPMIRPMGPGGPSPMGLQGPVRGPMGHQMVQMHPPPPPQQIQQQHPAPPVEMEVEENLQPTAAATATRQYPEGSLKSSILKPDEVLNRITKRMMSSCSVEEEALVAISDAVESHLRELITLMAGVAEHRVESLRIPENYVAIDDVKRQLRFLEDLDRQEEELRESREKESLIRMSKNKNSGKETIEKAKEMQRQDAEAKRNRDANAAAIAALSSNKTVKNKWENTGAATTAPRPRTVRVTTRDLHLLVNQDSRFTGTFIREKMSYGGPAVDTTI
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity).  TFIID recognizes and binds promoters via its subunit tbp-1, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity).  The TFIID complex consists of tbp-1 and TBP-associated factors (TAFs), including taf-4 (By similarity).  Essential for early embryonic development, probably acting via activating transcription initiation by RNA polymerase II, as part of the TFIID complex (PubMed:18854162, PubMed:11566890).  In early embryos, but not oocytes, remains, presumably inactive, in the cytoplasm as a result of binding to oma-1 (PubMed:18854162).  Upon degradation of oma-1, taf-4 is released and bound by taf-12, and the taf-4/12 heterodimer translocates to the nucleus and transcriptional repression is relieved (PubMed:18854162).  Involved in lifespan extension in a manner dependent upon mitochondrial function (PubMed:24107417).  Plays a role in modulating polyribosome formation (PubMed:30198021).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 4, TBP-associated transcription factor family member taf-4.
What is the protein family that this protein belongs to?
Belongs to the TAF4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localization is ubiquitous in one- cell and early two-cell embryos, then enriched in nucleus in all subsequent embryo stages (PubMed:18854162). Localization to the nucleus is prevented by interaction with oma-1 and is sequestered in the cytoplasm, following fertilization, and thus allows for transcriptional suppression in early embryos, but not in oocytes (PubMed:18854162). Localized to the nucleus in a taf-12-dependent manner (PubMed:18854162).
Protein: FAAA_MOUSE
Sequence: MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVEQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: CY550_PROMM
Sequence: MASLFASLGRSLIKLLIVLPVIIGLSISSPAMAAQWDAETLTVPAGSGGQQVTFTESEIKSASKLFKSNCATCHNQGVTKTNQNVGLDLEALSLASPARDNVDGLVEFLKNPMSYDGEYSIADTHPGISSSDVYVQMRTLNDEDLRLIAGYILTAEKVQGDQWGGGKIYF
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: CBY2_MOUSE
Sequence: MSPLECSECFGDQLLHKTYTWHLTLHSRPNFTRKRDTRSESLEIPVNVILPQRGTEPFLRLHNLYSTPRCSRQAALPRMSRRVASQHSYPLNRFSSMPFDPMERPTSQADLELDYNPPRVQLSDEMFVFQDGRWVNESCRLQPPYFSPPSSFHHKLHHRRLAKEYQLQEENKSLRDENRALRDENKALRKENKILQVFWEEHKVTLGHEESQTSSLLHKDTTSQEVVKRDNTTLPAQRSKESTLQLIREENRALQQLLEQRQAYWAQAEENAASTEEGKSTSSPKEESHNSGLLPDQSTNHSSPFEDPKVPPTTQEDSKTLRALREMVNNLSGASGEEDGKVGPNLPDSAQPLQLLREMNQALQALQEENRLLQEENRALHILREEHRVFQEENKALWENNKLKLQQRLVIDTVTEVTARMEMLIEELYAFMPAKNNKDPKKPSRV
What are the official names of this protein?
Protein chibby homolog 2, Protein nurit, Spermatid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the chibby family. SPERT subfamily.
Protein: CS13A_LACNK
Sequence: MKISKVREENRGAKLTVNAKTAVVSENRSQEGILYNDPSRYGKSRKNDEDRDRYIESRLKSSGKLYRIFNEDKNKRETDELQWFLSEIVKKINRRNGLVLSDMLSVDDRAFEKAFEKYAELSYTNRRNKVSGSPAFETCGVDAATAERLKGIISETNFINRIKNNIDNKVSEDIIDRIIAKYLKKSLCRERVKRGLKKLLMNAFDLPYSDPDIDVQRDFIDYVLEDFYHVRAKSQVSRSIKNMNMPVQPEGDGKFAITVSKGGTESGNKRSAEKEAFKKFLSDYASLDERVRDDMLRRMRRLVVLYFYGSDDSKLSDVNEKFDVWEDHAARRVDNREFIKLPLENKLANGKTDKDAERIRKNTVKELYRNQNIGCYRQAVKAVEEDNNGRYFDDKMLNMFFIHRIEYGVEKIYANLKQVTEFKARTGYLSEKIWKDLINYISIKYIAMGKAVYNYAMDELNASDKKEIELGKISEEYLSGISSFDYELIKAEEMLQRETAVYVAFAARHLSSQTVELDSENSDFLLLKPKGTMDKNDKNKLASNNILNFLKDKETLRDTILQYFGGHSLWTDFPFDKYLAGGKDDVDFLTDLKDVIYSMRNDSFHYATENHNNGKWNKELISAMFEHETERMTVVMKDKFYSNNLPMFYKNDDLKKLLIDLYKDNVERASQVPSFNKVFVRKNFPALVRDKDNLGIELDLKADADKGENELKFYNALYYMFKEIYYNAFLNDKNVRERFITKATKVADNYDRNKERNLKDRIKSAGSDEKKKLREQLQNYIAENDFGQRIKNIVQVNPDYTLAQICQLIMTEYNQQNNGCMQKKSAARKDINKDSYQHYKMLLLVNLRKAFLEFIKENYAFVLKPYKHDLCDKADFVPDFAKYVKPYAGLISRVAGSSELQKWYIVSRFLSPAQANHMLGFLHSYKQYVWDIYRRASETGTEINHSIAEDKIAGVDITDVDAVIDLSVKLCGTISSEISDYFKDDEVYAEYISSYLDFEYDGGNYKDSLNRFCNSDAVNDQKVALYYDGEHPKLNRNIILSKLYGERRFLEKITDRVSRSDIVEYYKLKKETSQYQTKGIFDSEDEQKNIKKFQEMKNIVEFRDLMDYSEIADELQGQLINWIYLRERDLMNFQLGYHYACLNNDSNKQATYVTLDYQGKKNRKINGAILYQICAMYINGLPLYYVDKDSSEWTVSDGKESTGAKIGEFYRYAKSFENTSDCYASGLEIFENISEHDNITELRNYIEHFRYYSSFDRSFLGIYSEVFDRFFTYDLKYRKNVPTILYNILLQHFVNVRFEFVSGKKMIGIDKKDRKIAKEKECARITIREKNGVYSEQFTYKLKNGTVYVDARDKRYLQSIIRLLFYPEKVNMDEMIEVKEKKKPSDNNTGKGYSKRDRQQDRKEYDKYKEKKKKEGNFLSGMGGNINWDEINAQLKN
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  Unlike many single-component effectors, this CRISPR-Cas system targets RNA (PubMed:28475872).  CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:28475872).  Cleaves linear target ssRNA in a pre-crRNA-dependent fashion, preferentially around A residues (PubMed:28475872).  Binding a viable target RNA target activates this protein for non-specific RNA degradation in vitro (called collateral RNA degradation), but it is not very sensitive as it requires nanomolar levels of viable target RNA (PubMed:28475872).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas13a, EndoRNase, LbaCas13a.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas13a family.
Protein: SYR_CLOK5
Sequence: MDFKKLAAEEIKKNIDLELNFIEGLIEVPPKPEMGDYAFPCFQLAKVLKKAPNIISKELKDKLHSKYFEKIENLGPYVNFFVDKKIFTEYTLKEILLKGDSYGSSDMGEGKNVVVEYSSPNIAKPFHVGHLFSTSIGNALYKMINFQGYNCTRINHLGDWGTQFGKLIAAYNRWCNAEELNRDPIKELLRIYVKFHEEAEKDPSLNEEGRMYFKKLEDGSEEEIKLWKKFKDLSLREFKKVYDLLKVDFDSYAGESFYTDKMDAVVEEIDKKGLLVESNGAKVVLLDEYNIPPCIVKKSDGTTIYATRDLAAAIYRKKTYDFYKSIYVVGLDQSLHFKQVFTTLKLMGKDWADSCKHVGFGLVRFANKKLSTRKGDVIFLEELLNKSVERTLEIINEKNPKLENKEEAAKKIGIGAVIFTYLKNNREKDIVFDWNEMLSFEGETGPYVQYSYARGKSILRKSEEASYDENQIDYSKLGSKEEFELVKILENFNKSIINAINRLEPFIVTRYVIDVAKAFNKFYNAHSIMNAADENIKKARLYLVKCTCQVLKNGLNLMGIEVVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_BARHE
Sequence: MKDEHIAVLMGGFSSERSVSLSSGTACADVLEAQGYRVSRVDVDGHIASVLEQLQPDIAFNALHGPFGEDGRIQGVLEYLKIPYTHSGVMASALAMDKGRAKIVVASVGVSIAPSCVMSRFAVGKEHPMEPPYVIKPVCEGSSLGVIIVKENESVPSLNVVGSEWVYADTVIVEKYIPGRELTCAVMGNKALDVCEILPEKHFQFYDYDSKYKSGGSLHVCPAQLSSNIYQNVQRMSLAAHQAIGCRGVSRSDFRFDEETGELVWLEINTQPGMTPTSLFPDIAKASGRTYGDIVQWMVEDASCMR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK2C_ARATH
Sequence: MYRERGMVGSKSEVVDRKRINEIHDNRPSHSMSQPVNGKGKVTSTSVLMGKQQLHDKESSRSGSISKTNISDAVDISDTDSEESEVSGSDGEDTSWISWFCNLRGNEFFCEVDDDYIQDDFNLCGLSHQVPYYDYALDLILDVESSHGEMFTEEQNELIESAAEMLYGMIHARFILTSKGLASMLDKYKNYDFGRCPRVYCCGQPCLPVGQSDIPRASTVKIYCPKCEDVYYPRSKYQGNIDGAYFGTTFPHLFLMTYGHLKPQKASQSYTQRVFGFKLHKP
What is the function of this protein?
Plays a complex role in regulating the basal catalytic activity of the alpha subunit.  The tetrameric holoenzyme CK2, composed of two alpha and two beta subunits, phosphorylates the transcription factor PIF1 after an exposure to light, resulting in a proteasome-dependent degradation of PIF1 and promotion of photomorphogenesis (PubMed:21330376).  CK2 phosphorylates translation initiation factors.  May participate in the regulation of the initiation of translation (PubMed:19509278).
What are the official names of this protein?
Casein kinase II subunit beta-2, CK II beta-2.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: TORD_SHIB3
Sequence: MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFAARCHQYDSFGFYAALSQLLLVLVECDHQNK
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.