PharMolix/UniProtQA huggingface dataset:
Protein: NUDC_PECAS
Sequence: MEQTLKGDETGWWVVSDAVQIWMPQGELPRGTATEWSLQGKTARQIGEWQGQPAWLVCQGRDTDMASVRQLLDQDVGLFQLAGRGVQLAEFYRSHRFCGYCGHEMVRSKTELACLCHHCKERYYPQIAPCIIVAIRRGEEILLAQHNRHRGNMYTVLAGFVEVGETLEQTVVREVMEESQIQIKNLRYVSSQPWPFPHSLMMAFMADYAGGDIKHDPKELRDAGWFRYDQLPQLPPPGTVARRLIEDTVVLCRAYHENEG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: GLMU_STRPF
Sequence: MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAINPEKAVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILRDFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGGSRQVTKEGYAKRLAHHPSGSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_SYNY3
Sequence: MTATAVKTDYEAIIGLETHCQLNTASKIFCNCSTDFDSPPNTNVCPVCLGYPGVLPVLNEEVLAAAVKLGLAINGQIAPYSKFDRKQYFYPDLPKNYQISQFDLPIVEHGSLEIELVDKKTKEITRKTIGITRLHMEEDAGKLVHAGSDRLAGSTHSLVDFNRTGVPLLEIVSEPDLRTGQEAAEYAQSLRQLVRYLGISDGNMQEGSLRCDVNISVRPVGQKEFGTKVEIKNMNSFSAIQKAIEYEIERQIKAIADGEEIYQETRLWEEGSQRTISMRKKEGSSDYRYFPEPDLPPLEVSEQQKQTWFATLPELPSAKRARYEQKLGLSAYDARVLTEDRDVALYFEEAVNAGADPKAVANWVTQDIAAYLNNNRLTISGLALKPSALAELIDLITKGTISGKIAKDILPELLEKGGSPQKIIEARGLVQISDPDELTAIIQAVIADHPKELEKFRSGKGNMQGFFVGQVMKRTGGKADPKLTNQLIGKLLAQA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LAP4B_HUMAN
Sequence: MTSRTRVTWPSPPRPLPVPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRSRQQRRGGLQARRSTLLKTCARARATAPGAMKMVAPWTRFYSNSCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPDQYNFSSSELGGDFEFMDDANMCIAIAISLLMILICAMATYGAYKQRAAWIIPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNFPYRDDVMSVNPTCLVLIILLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATVNGAAKEPPPPYVSA
What is the function of this protein?
Required for optimal lysosomal function (PubMed:21224396).  Blocks EGF-stimulated EGFR intraluminal sorting and degradation.  Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation (PubMed:25588945).  Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stimulating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation (PubMed:25998567).  Plays a role as negative regulator of TGFB1 production in regulatory T cells (PubMed:26126825).  Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways (PubMed:26280656).
What are the official names of this protein?
Lysosomal-associated transmembrane protein 4B, Lysosome-associated transmembrane protein 4-beta.
What is the protein family that this protein belongs to?
Belongs to the LAPTM4/LAPTM5 transporter family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Late endosome membrane. Cell membrane. Cell projection. Lysosome membrane. Endosome membrane. Endosome, multivesicular body membrane. Endosome, multivesicular body lumen.
Protein: PYRH_GLUOX
Sequence: MMTENREQSPSYKRVLLKVSGEALMGDGPSGVDPVMVDMVAADIADVVASGVEVCLVVGGGNIFRGLAAAAKGMDRAQGDYAGMLATVINALMLQNALERRGMETRVMTAIQMAAIAEPYIRRRAVRHMEKGRVVIFAAGTGNPFFTTDTAAALRANEMECDALFKGTQVDGVYSADPRRNPDAERYDQLTYLEVLARDLNVMDAAAISLARENKLPIVVFNMHAPGSFGAVMRGEGLFTKIIEAD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_SALA4
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: GAR1A_MOUSE
Sequence: MSKIRGLPPAIRDPGPGVELGVVDGLLCQLIHSPEFNLFSDSVVFESTFIQVTKQGNWMDAYERSATMILGVTSSVPSLPLPNILLMANVTWPHGPFSTCSTLGAPVITLSRILPLKYVELQIYDRTQRILRVRTVTEKIYYLRLHEKHPQAVFQFWIRLVKILQKGLSITTKDPRIQFTHCLVPKMSNSSTETATESSLPASSQNSEAIMLLAAERNSSSLLELSNRHQTSRDRHTDTATETDNSGNCKSTPLVASSASMPMRAALTHSLWEQEDSNENFLQAPVASSLGENLLGP
What is the function of this protein?
RAB2B effector protein required for accurate acrosome formation and normal male fertility.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 1A.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: SCRK7_ARATH
Sequence: MGEDAISGNLKNLTIDTRDSETLVVCFGEMLIDFVPTVGGVSLAEAPAFKKAPGGAPANVAVGVSRLGGSSAFIGKVGDDEFGRMLADILRLNNVDNSGMRFDHNARTALAFVTLRGDGEREFLFFRHPSADMLLLESELDKNLIQKAKIFHYGSISLIEEPCRSTQLVAMKIAKAAGSLLSYDPNLRLPLWPSEEAARKEIMSIWNLADVIKISEDEITFLTGGDDPYDDDVVLQKLFHPNLKLLVVSEGPNGCRYYTQEFKGRVGGVKVKPVDTTGAGDAFVSGLLNSLASDLTLLKDEKKLREALLFANACGAITVTERGAIPAMPSMDAVQDLLSSTRS
What is the function of this protein?
May play an important role in maintaining the flux of carbon towards starch formation.
What are the official names of this protein?
Probable fructokinase-7.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: Y2368_STAAM
Sequence: MKRLVTGLLALSLFLAACGQDSDQQKDSNKEKDDKAKTEQQDKKTNDSSKDKKDNKDDSKDVNKDNKDNSANDNQQQSNSNATNNDQNQTNNNQSSNNQKSSYVAPYYGQNAAPVARQIYPFNGNKTQALQQLPNFQTALNAANNEANKFGSNNKVYNDYSIEEHNGNYKYVFSFKDPNANGKYSIVTVDYTGQAMVTDPNYQQ
What are the official names of this protein?
Uncharacterized lipoprotein SAV2368.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CCD25_MOUSE
Sequence: MVFYFTSSSVNSSTYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKLEKFPDLAAEKEGRDREERNEKKAQIQEMKRKEKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM
What is the function of this protein?
Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility.  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Formation of NETs is also associated with cancer metastasis, NET-DNA acting as a chemotactic factor to attract cancer cells (By similarity).  Specifically binds NETs on its extracellular region, in particular the 8-OHdG-enriched DNA present in NETs, and recruits ILK, initiating the ILK-PARVB cascade to induce cytoskeleton rearrangement and directional migration of cells (By similarity).  In the context of cancer, promotes cancer metastasis by sensing NETs and promoting migration of tumor cells (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 25.
What is the protein family that this protein belongs to?
Belongs to the CCDC25 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system. Note=Localizes to cytoplasmic membrane in tumor cells.
Protein: CWP30_TOBAC
Sequence: NPQYPXGNVQ
What are the official names of this protein?
50 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PUR5_LACAC
Sequence: MNRYKEAGVDVTAGYDLVNRIKPLVAATKRKGVMGSIGSFGGMFDLEELGYKHPVLVSGTDGVGTKLMIAQKMHKNDTVGIDCVAMCVNDVLAQGAEPLFFLDYIACGHNDPERLADVVKGVAEGCKQSGSALIGGETAEMPDMYEPHEYDLAGFSTGIAEKEDLLSSSLAKAGDHLIALPSSGVHSNGFSLIRKILFKDHDVSLDDKPAELSGKTVGETLLTPTRIYIKAVLPLVKKHLIHGIAHITGGGFIENLPRIYDDNLQAVINKGSWPGLPIFDYLKKIGVLSDQDCYNTFNMGIGLVLAVSSENVDAVKEQLNTENEEFYEIGKLTARPAGKAKIVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA2_STAAS
Sequence: MKHKLDVTINELRLKSIRKIVKRINTWGDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNLYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: UBE2W_RAT
Sequence: MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGENIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWWYHDDTC
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  Specifically monoubiquitinates the N-terminus of various substrates, including ATXN3, MAPT/TAU, POLR2H/RPB8 and STUB1/CHIP, by recognizing backbone atoms of disordered N-termini.  Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3.  After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway.  In vitro catalyzes 'Lys-11'-linked polyubiquitination.  UBE2W-catalyzed ubiquitination occurs also in the presence of inactive RING/U-box type E3s, i. e.  lacking the active site cysteine residues to form thioester bonds with ubiquitin, or even in the absence of E3, albeit at a slower rate.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 W, E2 ubiquitin-conjugating enzyme W, N-terminal E2 ubiquitin-conjugating enzyme, N-terminus-conjugating E2, Ubiquitin carrier protein W, Ubiquitin-protein ligase W.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: AROC_SHISS
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWSLVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KGUA_PSEPF
Sequence: MTHSTGTLYIISAPSGAGKSSLVKALTDTNPDIRVSISHTTRAMRPGEVDGVNYHFVTREEFVKMGEHGDFLERAEVFGNFYGTSQSRLQQTLDEGHDLILEIDWQGAEQVRKLMPQARSIFILPPSLQALHQRLTNRGQDSDEIIDGRMREAVSEMSHYVEYDYLIINDDFAHALDDLKAIFRANQLQQKRQQVRFGKLLAELLG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_STAEQ
Sequence: MDNSLHATTIYAVRHNGEAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMNKDAILIVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHAAQLSASEMAYESLKVAADICVFTNDNIIVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6496_DICDI
Sequence: MSIFSSLSSLSTGSLKSSVSSIENGSSSGSFGSNETSGWGQHHWNSCRPCPPPRPICRPCPPPCHPKPRCHY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285443.
Protein: HMUDK_BPW14
Sequence: MSNTLHEGFKFGDPGLINIRGTNGSGKSTIVKRYIPKGAVQKRFDDIGTTYYDCGTHFVVGRYETDCGGLDAVRGTYDPKTGQGIRPFEAGQIAIGRLAPLKTTFAEGVIYGTTFKGSKEVHDELAKTNTPYFWFSIDMPFQEVFDSVLLRRVKSGNADPLSTENIAKKFRPVLASLDKAVDAGLWTIYGHRDVIAQNVDDLVNNRPLTNADLIGRKPDLTKFNKEAQVWFDKGTVSPTQEMIDEHFPKPTTHGLGGFFKG
What is the function of this protein?
Phosphorylates 5-hydroxymethyluracil (5hmdU) into 5-phosphomethyl-2'-deoxyuridine (5- PmdU) on DNA as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-Nalpha-putrescinylthymidine (Nalpha-PutT) substitutes for about 50% of thymidines in the viral DNA (PubMed:34522950).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
5-hmdU DNA kinase, 5-hydroxymethyluracil DNA kinase, P-loop kinase, gp37.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family. 5-hmdU DNA kinase subfamily.
Protein: RHAM_ENTFA
Sequence: MIKKAFCMQVYPDQHAEYQRRHEKLWPEMRQMLKEHGAIKYQIFLNPETSTLFGYLEIEDEARWEQIALTPINQKWWNYMEDIMETNPDCSPMTAELKKVFEL
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMF1_BOVIN
Sequence: MAEASSVNVGSGCAEKGPEELSQEPARPGTNISRVKLFDTMVDTFLQKLVAAGSFQRFTDCYKRFYQLQPEMTQRIYDKFVTQLQTSIQEEISEIKAEGNLEAVLIALDAIVEESKDRKEQAWRPSGIPEKDLRSAMAPYLLQQRDALQRRVQRQEAENRQLADAVLAGRRQLEELQLQAQARQQAWQALHREQKELLAVLKEPE
What is the function of this protein?
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.  May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT (By similarity).
What are the official names of this protein?
Polyamine-modulated factor 1, PMF-1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Protein: COOS1_METMA
Sequence: MGCKMKQTAFEKSIDPASQKMLEKAENEGIETAWDRYEKQLPQCSFGQLGICCRNCNMGPCRIDPFGEGAEKGICGATADIIVARNLLRMIAAGAAAHSDHARDAVLTFKKMTEGEAGSYGIKDKTKLFSLASEYGISLEGKSHEEVAGELASALLAEFGKQEGPIQYTRRAPEARLRLWTSLGIEPRGVDREIVECMHRTHIGVDNDATHILLHGLRTSLSDGWGGSMIATEIQDVLFGTPEPKKSTVNLGVLSHDKVNVIIHGHEPILSEMIVQAAEDPELLELAKEKGAAGINVAGICCTGNETLMRHGTPIAGNFLQQELAVVTGAVEAMIVDVQCIMPALGNLTGCYHTKFISTSPKADFPGTVRMEFHEERAYDTAREIVRTAVENFPNRNIEKVNIPEEKQECMVGFSAEAILKALGGSPAPLIDAIAGGAVKGIGAVVGCNNVKVQHNYGHVNLVKELIKNNVLVVTTGCNAIACAEAGLLVPEAAAQAGDGLKGVCEALGIPPVLHMGSCVDISRILVLASAIAKSLGVDISDLPAAGAAPEWMSEKAVSIGAYVVSSGVFTVLGTVPPVLGSQAVTALLTKGLDNVIGASFAVEPDPFKAANLMLEHIEGKRKALGLN
What is the function of this protein?
CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
What are the official names of this protein?
Carbon monoxide dehydrogenase 1, CODH 1.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: AROA_METM6
Sequence: MLVVKKTPKINGILNAPPSKSYTHRAVICASLANGLSNLKNPLNGADCLSSAHACEMFGAEIELSDEQWVIRGSELKTPDNIVDIGNSGTTLRILTGISSQISNGYTILTGDDSIRKRPMQPLLDALKQLGIESFSTKNNGTAPIVVKSGKISNNVVEIRGDMSSQFITSLMMTLPFSENDSKIVLTTPLKSEPYLNITIDVLDKFGVKIEKNEEKNKLGYKIKGNQRYSPCEYIIEGDYSSASYLVAAGVLLNSDIVIKNVFKNSKQGDREIIEIVKKMGADVEINEDNVKITGPYNLKGIEIDVTDIPDLVPTIAVLGCFAEGKTVVYNGEHVRIKECDRLAACTLELSKMGAEIEEKKDGLIITGVHKLNGAKLKTYHDHRLVMAFTIAGMLADGETIIEGEDSVKISFPDFVDKMKSIGSNIEVI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOM_CLAPU
Sequence: MLILLLQYNVSNPCLTNLLENKTGTGVGLNFPLKPARLTLAQQRKRSELKKARLALRGMGIGDFNRELRFYSTSAYTKTHWNNKDRINKWMQYDIFVDRDFESFLSHLFSDNRILFEYTYALLVKVRKGNKFYTIGDRQIGVLFVDIHDPFLLEVFDTIIDRLAILFEEYPTELEYTCDALLLEFHPVRPEKIKISNLKDAKEKLAPKTFATGMSVFNLIGGFDLRKVSTPINLNKKRYYSTQVDRLNGFITDNPRLLEFKQKFNEQLFMASPKKKLKYEFCDTSVVFILVKRGREYIVIEDVKDGEFHKRIFNKTASLLLHLIDKSNGDGTWTRINGNFNTLYNLENEIIMSTKAIGLRAIPKFLYNKKNEEEMSVLANPNLGTIDLETTTGAQPKCYAIGFYTNLDSKPIKFYIDKNLDSCQLVHTCIQEMMRYKYRNVLFYAHNLGKFDAVFLLKELLRFNLTTEGLNNPYEFPAPLTRNSDILKLTIKRTVDGKTRKVTIMDSFALLPRSLRDLCKDYNIDNPKSYFPYLFSVDSHLFYTGATPNINYYLDIPKAEYLKLVKDDWDFKDETLEYLNLDLISLHQVLVKVNKAINFLFDIEFTSCATVSSLANKIFLSKFYDDKNKAIPLVKDIDLFNDIHEAYYGGRVEVFNPIIMADSTKSYYYYDVNSLYPFASINDIPGLKCTFYEVVKANVNIHELFGFFYCKIKSPDNLYLGLLPKRTETSLIFPGGAWEGWYFSEELKFAVAHGYEVEIIKGYNFDRVSNVFNEFVQEVYKVKCNPNNVTEKNIAKLILNSLIGRFGMNINKIKTSLVPSEKHNELLTTRVVKSTTDLGSGMFMDIYVPGIDKNICEDFNLDYIEVLNSTNTDEKGTMPDNNVSITTAAAVLSYARIHMAQIMLFILENNGTLYYTDTDSIVTDLKLPEEMVHQTEIGKLKLEHTITQGYFIADKTYAIVNTEGEIIKRAKGVKSSKLTLEDYEKMYNKEVVEATKTSSKRNYKDGFVTISDSTVKLNPTSYTKRSRVISKDKWIGTEIIRLDKLNSKLSTHTPKSLSGDKTK
What are the official names of this protein?
Probable DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL35_VIBC1
Sequence: MPKMKTNKGAAKRFKKTAGGIKYKHATKRHILTKRTTKNKRQLRPNALLPRCEVAAVVRMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GATA_SYNSC
Sequence: MDRRDMTISAWRQQLQSGEVSSRELVDQHLKRLESSEPSLNAFVEVTADQARAEASRIDEARAAGEALGPLAGLPLAIKDNLCTKGVRTTCSSRMLEQFVPPYESTVTERLWQAGGVLVGKTNLDEFAMGGSTETSAFGATQNPWNTAHVPGGSSGGSAAAVAAGSCVASLGSDTGGSIRQPASFCGVVGLKPTYGRVSRWGLVAFASSLDQVGPFAGSVADVAELLQVIAGPDPRDSTCLDAAVPVFSDGLSQSIKGLKVGLIKECFDAEGLDPEVKASVQASAAQLEALGAELVEVSCPRFNDGIATYYVIAPSEASANLARYDGVKYGFRAEDAESLAAMTARSRAEAFGAEVQRRILIGTYALSAGYVDAYYKKAQQVRTLIRRDFDAAFKSVDVLLTPTAPSTAFKAGAHADDPLAMYLADLLTIPVNLAGLPAISVPCGFSAAGLPIGMQLIGNVLDEPRLLQVAHQYEQAAQVFASRPEAALVP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.