PharMolix/UniProtQA huggingface dataset:
Protein: THYX_CORDI
Sequence: MAQQSLLDVQLVACSTFTTPSGVDWKVDSAATDSEALVEFAGRACYETFDKPNPRTAANDAYIRHIMEVGHMALLEHPTATVYIRGLSRSATHELVRHRHFSFSQLSQRFVHSDETHVVIPPLIDNDPQLRELFLSTVDEVRFAYSELMTALDNKLADEPNAILRRKQARQAARSILPNATESRIVVTGNFRAWRHFIGMRATEHADVEIRSLAVRCLEILKEKAPTVFSDFETSVLSDGSIMATSPYVTDY
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: THIC_ALIF1
Sequence: MSSSRKQARLDAKTNIESLSVQPYPNSNKVYIEGSRPDIRVPMREISLADSLVGGTKESPIFEPNEPIQVYDTSGVYTDPSYDIDVYKGLPKLRQEWIEERNDTELLDGVSSVYSQERLADETLDELRYGNLPTIRRAKQGQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHSFGANLPKEITPEFVRREVAEGRAIIPSNINHPEAEPMIIGRNFLIKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKTGLITYKLAAHAGDLAKGHPGAQIRDNALSKARFEFRWEDQFNLSLDPITAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDSEQVALDQAIEIKMIDDPLEGMRQKSEEFKASGSELYHPVVEAE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MRAZ_YERPE
Sequence: MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCLLLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQGLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MATK_ABIFI
Sequence: MDEFHRYGKEDSSWQQCFLYPLFFQEDLYAIYHDHYLDGSSSSESMEHLSSNDQFSFLTVKRLIGQIRQQNNSIVFFLNCDPNPLVDRNKSFYYESVLEGLTLVLEVPFSIRSKYSVEGMNEWKSFRSIHSIFPFLEDKFPHSNYILDTRIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYKYRNSPDNLQKSIIIDPRVNTRFLLFLWNHYVYGCESILVPLLKRSFHPRSLSHGSFPDQTHFDRKIKHIIRNYRRNSLKSIWSLKDPRIHYVRYAERSIIAIKGTHLLVKKCRYHLPIFRQFYFHLWSEPYRVCSHQLSKNCSSSLGYFLRVRMKPLLVRTKMLDELFITDLITDEFDPIVPIVPIIGLLAREKLCDISGRPISKLYWTSLTDDDILDRFDRIWKNIFHYYSGSLDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKYFSKEREFDFPAFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPS9_DICPU
Sequence: MSLSFKNIVFPEEWQVPPNDYIFIDDCYEEALQFNLFERGDEKSYTWMYHTISCCAYFWCKCSRSEMKLIGHLMLWTFLLDDILDSDKVNDAEAIEMIKRTEFIFIEGKLPENPTDLEKYTCYLRNEGLKIAGDREDMFNMFLTNSIQWILSIIPLNKSMEHKLPPHLQLHGYLRKLNVGVELCQGFTYLIFANNKVNPAIFNSPRYKKMLECTSMVVSHVNDMASYCKEVKNGGGFINSLLILQKRADPLSIEHSYQVIAEQTNAFIRDFIYQEKMLLESISDEQQNEVKVFLDHMKYLMKGNYLWSGTTARYASKSSPFVEMQKSLNVHLDNEIDASSL
What is the function of this protein?
Terpene synthase that converts its substrate farnesyl diphosphate (FPP) into the sesquiterpenes beta-elemene, germacrene D and a yet unidentified sesquiterpene.
What are the official names of this protein?
Terpene synthase 9.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: EFG_LEPBL
Sequence: MSTAVAEFKPSEKLLKTRNIGISAHIDSGKTTLTERILFYTNRIHAIHEVRGKDGVGAKMDSMDLERERGITIQSAATYCQWKNHTINIIDTPGHVDFTVEVERSLRVLDSAILVLCGVAGVQSQSITVDRQMRRYNVPRVAFINKLDRTGANPFRVIEQLKEKLKHNAVPVQIPIGLENDLKGVVDLVTMKAYYFEGKDGMDIQEKEIPDDLKELANKKHEELLDAASMFSDELTEALLEGTPTEEMIKKAIRTGTIELKITPVFMGSAFKNKGVQKLLDGVLDYLASPVDVKNKALDQNNNEEMIVLESNYEKPLVCLAFKLEDGRYGQLTYVRVYQGKLSKGMTIYNMSNNKKHNVGRLCRMHSDEMEDIDSAEAGDIIALFGIDCASGDTFTDGKLKVSMESMFVPAPVISLTIEAKESKHLNNLAKALNRFTKEDPTFQTHVDPESGQTIIKGMGELHLEVYIERMKREYGVELITGAPQVAYRETITSKADFDYTHKKQTGGQGQFGRVAGYMEPIPLEETLDYDFVNKVVGGAIPREYIQSVDKGFKSCLERGSLIGFPIIGVRCVINDGAYHDVDSSDMAFQIAGRYAFRQGFNKANPQILEPIMKVEVDGPSEFQGAILGSLNQRRGMILNTTEEDAYCKTEAEVPLADMFGYSTVLRSSTQGKAEFSMEFSRYAPVPRNVAEELMKKYKVNNKDED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORR8_ORYSJ
Sequence: MSSPHVLVVDDTHVDRHVVSMALMRHNVRVTAVESVMQALMFLDSEHDVDMIVSDYCMPDMTGYNLLMEVKKSPKLAHLPVVIASSDNIPERIRKCLDGGAKDYILKPVKIVDVPRIMKYI
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR8, OsRR8, OsRRA13.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
Protein: APAH_SALNS
Sequence: MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: TRP5_PYRAP
Sequence: APVMGFQGMR
What are the official names of this protein?
Tachykinin-related peptide 5, TKRP-5.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEG_ENTFA
Sequence: MPTLKEKIIQESQRLGIDKIGFTHAEPFIELEDSLHEQRERGYNSGFEHQNVEERIYPEKTFEHPKSIISIALAYPTKAQEKMPRDEKRGQFARASWGIDYHHILQDRLQKLIAFIEEQAATEAEKEHWRFRPQVDTGEYVDTAVAQRAGLGFIGKNGLLITEEFGSFVYLGEVTTNIQFEPDEPVPNGCGDCTRCITGCPTGALLGDGRMNAQKCLSYQTQTKGMMPEDYRKKMRNVIYGCDICQLVCPYNKGKDFHFHEEMEPKIEEVYPKLAPLLTISNKEFKQQFGHLAGSWRGKKPLQRNALIALANLGGREAIPQIILCLNDQRPVIRGTAAWSLGQLAKREPEQSLEALNYLLSVETEEEVIEEAQKAIHLLTSKKGSRSTE
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASB3_HUMAN
Sequence: MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKEWLPHLLVAGFDPLILLCNSWIDSVSIDTLIFTLEFTNWKTLAPAVERMLSARASNAWILQQHIATVPSLTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYEDVLRMYEVPELAAIQDG
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes TNFRSF1B.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 3, ASB-3.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: MIC12_YEAS8
Sequence: MSKLGPLARSVKWTLSVGVIGSVFYLYRYSNNGYFYDHDATWLKQDHQVQDLVDRKEVVPGETRNRKLVVTDDGTAWSRTMGESIKDIWNEQIRNSVDWIYSWGKN
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC12, Altered inheritance of mitochondria protein 5, mitochondrial, Found in mitochondrial proteome protein 51.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic12 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLNA3_MAIZE
Sequence: MACLTDLVNLNLSDTTEKIIAEYIWIGGSGMDLRSKARTLSGPVTDPSKLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDCYTPAGEPIPTNKRYNAAKIFSSPEVAAEEPWYGIEQEYTLLQKDTNWPLGWPIGGFPGPQGPYYCGIGAEKSFGRDIVDAHYKACLYAGINISGINGEVMPGQWEFQVGPSVGISSGDQVWVARYILERITEIAGVVVTFDPKPIPGDWNGAGAHTNYSTESMRKEGGYEVIKAAIEKLKLRHREHIAAYGEGNDGRLTGRHETADINTFSWGVANRGASVRVGRETEQNGKGYFEDRRPASNMDPYVVTSMIAETTIIWKP
What is the function of this protein?
Plays a role in the flow of nitrogen into nitrogenous organic compounds.
What are the official names of this protein?
Glutamine synthetase root isozyme 3, GS112, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_OROMI
Sequence: MFILRLFVYNVVIFFVFLFIFGFLPNDSGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: ILVD_SALSV
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNRNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLNEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PSBF_CYAPA
Sequence: MNNPNQPVSYPIFTVRWLAIHAIGIPAVFFIGSITAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: IMA2_YEAST
Sequence: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
What is the function of this protein?
Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose.
What are the official names of this protein?
Oligo-1,6-glucosidase IMA2, Alpha-glucosidase, Isomaltase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SPF27_MOUSE
Sequence: MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.  The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
What are the official names of this protein?
Pre-mRNA-splicing factor SPF27, Breast carcinoma-amplified sequence 2 homolog, DNA amplified in mammary carcinoma 1 protein.
What is the protein family that this protein belongs to?
Belongs to the SPF27 family.
Protein: SYT_NOVAD
Sequence: MSELLKITLPDGSVREVAPGSTPADIAAAIGPGLAKAALAAKVDGELVDLTRPFTADAQLALVTAKDEAEALDLARHDYAHVLAEAVQALFPGTQITFGPSTDDGFYYDFAPKDRPFTDEDLPAIEAEMRKIIAANKPLRREVWSREQLISRWKQQGESFKAEWAAELPENEELTVYWSGDDWLDMCRGPHLPSTGKLDPNAFKLTRVSGAYWRGDQKNAMLSRVYGTGWLNKKQLDAHLTRLEEAAKRDHRKLGNEMDLFHLQQEAHGSVFWHPKGYLIWRELEAYMRRAIDGAGYREVKTPQVMDARQWEQSGHWGKYRENMFVIPDEVPNVDDEGPIVSNDADWMALKPMNCPAHVLIFRQGIKSYRELPLRLYENGCCHRNEPHGALHGLMRVRQFTQDDAHIFCREDQIVSEVQAFCELADRIYKHFGFTYSIKLALRPEKRFGTEEMWDKAERELRDAVVRAGLATEEYGWEELPGEGAFYAPKLEWHLTDAIGRTWQVGTIQSDRVLPERLDASYIGEDGEKHRPVMLHRAIFGSYERFIGILIEHFAGRLPVWLAPVQAVVATIVSDADDYARDALAKLKAAGIRADTDLRNEKINYKVREHSLQKVPYLLVVGKREAEEGTVAIRILGEQHQKVMPLDEAIALLKGEATAPDLRA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCRM_TORMA
Sequence: MPFGNTHNKWKLNYSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEECYEVFKDLFDPVIEDRHGGYKPTDKHKTDLNQDNLKGGDDLDPNYVLSSRVRTGRSIKGIALPPHCSRGERRLVEKLCIEGLATLTGEFQGKYYPLSTMSDAEQQQLIDDHFLFDKPISPLLLASGMARDWPDGRGIWHNNDKSFLVWVNEEDHLRVISMQKGGNMKEVFRRFCVGLKKIEEIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVLKRTRLQKRGTGGVDTEAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKSIDDLIPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
What are the official names of this protein?
Creatine kinase M-type, Creatine kinase M chain, M-CK, NU-2 protein.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SHEPW
Sequence: MYNESPIIRRKSSRIYVGDVPIGDGAPIAVQSMTNTRTTDVAATVAQIKALENVGADIVRVSVPTMDAAEAFKLIKQQTNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKELMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIVQPLHLGITEAGGARAGSVKSAVGLGMLLADGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELEQRLEDVVTPMDVSIIGCVVNGPGEALISDIGLTGGNRMSGYYKDGVRQKERFDNNNIVDQLEAKIRAKVAMSESRIPAQDVTK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MTH3_HAEAE
Sequence: MNLISLFSGAGGLDLGFQKAGFRIICANEYDKSIWKTYESNHSAKLIKGDISKISSDEFPKCDGIIGGPPCQSWSEGGSLRGIDDPRGKLFYEYIRILKQKKPIFFLAENVKGMMAQRHNKAVQEFIQEFDNAGYDVHIILLNANDYGVAQDRKRVFYIGFRKELNINYLPPIPHLIKPTFKDVIWDLKDNPIPALDKNKTNGNKCIYPNHEYFIGSYSTIFMSRNRVRQWNEPAFTVQASGRQCQLHPQAPVMLKVSKNLNKFVEGKEHLYRRLTVRECARVQGFPDDFIFHYESLNDGYKMIGNAVPVNLAYEIAKTIKSALEICKGN
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GGCC-3', methylates C-3 on both strands, and protects the DNA from cleavage by the HaeIII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HaeIII, M.HaeIII, Cytosine-specific methyltransferase HaeIII, Modification methylase HaeIII.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: COAD_MYCTU
Sequence: MTGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMFDLDERIAMVKESTTHLPNLRVQVGHGLVVDFVRSCGMTAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLRDRLNTERT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMA1_MOUSE
Sequence: MHLLTLHLLLLLLGSSTKAGEIIGGTECIPHSRPYMAYLEIVTSENYLSACSGFLIRRNFVLTAAHCAGRSITVLLGAHNKTSKEDTWQKLEVEKQFLHPKYDENLVVHDIMLLKLKEKAKLTLGVGTLPLSANFNFIPPGRMCRAVGWGRTNVNEPASDTLQEVKMRLQEPQACKHFTSFRHNSQLCVGNPKKMQNVYKGDSGGPLLCAGIAQGIASYVHRNAKPPAVFTRISHYRPWINKILREN
What is the function of this protein?
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
What are the official names of this protein?
Chymase, Alpha-chymase, Mast cell chymase 1, Mast cell protease 5, mMCP-5, Mast cell protease I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Secretory granules.
Protein: LCE1A_HUMAN
Sequence: MSCQQSQQQCQPPPKCTPKCPPKCPTPKCPPKCPPKCPPVSSCCSVSSGGCCGSSSGGGCSSGGGGCCLSHHRRHRSHRHRLQSSGCCSQPSGGSSCCGGDSGQHSGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 1A, Late envelope protein 1.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: SYM_YERPA
Sequence: MAQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRFQRMRGNQVHFICADDAHGTPIMLKAQQMGIEPEQMIAEMSQEHQQDFAGFAISYDNYHSTHSDENRELSSLIYGRLKANGYIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKAPEQYGDNCEVCGATYSPTELIDPKSAVSGATPVMRESEHFFFDLPAFSDMLQAWTRSGALQEQVANKMQEWFDSGLQQWDITRDAPYFGFEVPDAPGKYFYVWLDAPIGYMGAFKNLCDKRGDLDFDEFWGKDAKTDLYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKAGTYLKYLDADCLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGQLADQLADPVLYKTFTDAATSIADAYNNRESGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLHAICSMGINLFRVLMTYLKPVLPSLTERTEAFLNTELTWDSIEQPLLGHSITAFKALFNRIDLDKVNEMVASSKEDMAPATRVTGPLADDPIQETISFDDFAKVDMRIALIQQAEFVEGSDKLLKLTLELGGETRQVFSGIRSAYPDPKALEGRMTVMVANLAPRKMRFGVSEGMVMAAGPGGSDIFLLSPDSGAQPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZMY19_MOUSE
Sequence: MTDFKLGIVRLGRVAGKTKYTLIDEQDIPLVESYSFEARMEVDADGNGAKIFAYAFDKNRGRGSGRLLHELLWERHRGGVAPGFQVVHLNAVTVDNRLDNLQLVPWGWRPKAEETSSKQREQSLYWLAIQQLPTDPIEEQFPVLNVTRYYNANGDVVEEEENSCTYYECHYPPCTVIEKQLREFNICGRCQVARYCGSQCQQKDWPAHKKHCRERKRPFQHELEPER
What is the function of this protein?
May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.
What are the official names of this protein?
Zinc finger MYND domain-containing protein 19, Melanin-concentrating hormone receptor 1-interacting zinc finger protein, MCH-R1-interacting zinc finger protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.