PharMolix/UniProtQA huggingface dataset:
Protein: PHS_BRADU
Sequence: MAERLTTEARKQALGGIPDWTEVSGRDAIGKTFVFKDFNEAFGFMTRAALVAEKMDHHPEWRNVYKTVEVVLSTHDAGGVTALDIELARAMNAIAKLTPG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: ODAD3_HUMAN
Sequence: MTSPLCRAASANALPPQDQASTPSSRVKGREASGKPSHLRGKGTAQAWTPGRSKGGSFHRGAGKPSVHSQVAELHKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIREWKWEKPYLKNRTGQALEHLDHRLREKVKQQNALRHQVVLRQRRLEELQLQHSLRLLEMAEAQNRHTEVAKTMRNLENRLEKAQMKAQEAEHITSVYLQLKAYLMDESLNLENRLDSMEAEVVRTKHELEALHVVNQEALNARDIAKNQLQYLEETLVRERKKRERYISECKKRAEEKKLENERMERKTHREHLLLQSDDTIQDSLHAKEEELRQRWSMYQMEVIFGKVKDATGTDETHSLVRRFLAQGDTFAQLETLKSENEQTLVRLKQEKQQLQRELEDLKYSGEATLVSQQKLQAEAQERLKKEERRHAEAKDQLERALRAMQVAKDSLEHLASKLIHITVEDGRFAGKELDPQADNYVPNLLGLVEEKLLKLQAQLQGHDVQEMLCHIANREFLASLEGRLPEYNTRIALPLATSKDKFFDEESEEEDNEVVTRASLKIRSQKLIESHKKHRRSRRS
What is the function of this protein?
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (PubMed:25192045).  Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (PubMed:25192045).
What are the official names of this protein?
Outer dynein arm-docking complex subunit 3, Coiled-coil domain-containing protein 151.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SRP54_METMA
Sequence: MVMEKLGDSLQGALKKLIGAGRIDERTVNEVVKDIQRALLQADVNVKLVMGMSQRIKERAMKEDPPAGMNPREHVIRIVYQELMEIIGKGADIQLKPQTIMMVGLQGSGKTTSAAKLARYFQRKGLKAGVVAADTFRPGAYHQLKTLSEKLNVGFYGEEGNPDAVEITIHGLKALEKYDIKIVDTAGRHALEADLIEEMERIHAVAKPDHKFMVLDAGIGQQASQQAHAFNDSVGITGVIITKLDGTAKGGGALSAVSETKAPIAFIGVGETPEDFEKFEADRFISRLLGMGDLKSLMEKAEESLSEEDVNVEALMQGRFTLKDMYKQLEAMNKMGPLKQIMSMLPMGMGGLGGVKLSDEMFQATSDKMKNYKVIMDSMTEDEMADPKLIGGSRIKRISRGSGCSPEDVRELLKYHKTMQTALKGFRGGKFNIQKMMKKKMGM
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: TM14B_HUMAN
Sequence: MEKPLFPLVPLHWFGFGYTALVVSGGIVGYVKTGSVPSLAAGLLFGSLAGLGAYQLYQDPRNVWGFLAATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAAKVGVRMLMTSD
What is the function of this protein?
Primate-specific protein involved in cortical expansion and folding in the developing neocortex.  May drive neural progenitor proliferation through nuclear translocation of IQGAP1, which in turn promotes G1/S cell cycle transitions.
What are the official names of this protein?
Transmembrane protein 14B.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
Protein: ETR2_ORYSI
Sequence: MPPIPSLWIRVFFSWLLLSLPAAAAADFSHCGGCDDGDGGGGIWSTDNILQCQRVSDFLIAMAYFSIPLELLYFATCSDLFPLKWIVLQFGAFIVLCGLTHLITMFTYEPHSFHVVLALTVAKFLTALVSFATAITLLTLIPQLLRVKVRENFLRIKARELDREVGMMKRQEEASWHVRMLTHEIRKSLDRHTILYTTMVELSKTLELQNCAVWMPSESGSEMILTHQLRQMETEDSNSLSIAMDNPDVLEIKATKDAKVLAADSALGIASRGKLEAGPVAAIRMPMLKASNFKGGTPEVMETSYAILVLVLPEDGSLGWGEEELEIVEVVADQVAVALSHAAVLEESQLIREKLAAQHRDLLRAKHETTMATEARNSFQTAMYDGMRRPMHSILGLVSMMQQENMNPEQRLVMDAIVKTSSVASTLMNDVMQTSTVNREYLSLVRRAFNLHLLVKEAISVVRCLTGCKGIDFEFEVDNSLPERVVGDEKRVFHIVLHMVGTLIQRCNAGCLSLYVNTYNEKEERHNQDWMLRRANFSGSYVCVKFEIRIRESRGNLLSSSSSRRLQGPNSTSSEMGLSFNMCKKIVQMMNGNIWSVSDSKGLGETIMLALQFQLQHVTPVSGASSDLFRSAPIPNFNGLQVILVDSDDTNRAVTHKLLEKLGCLVLSVTSGIQCINSFASAESSFQLVVLDLTMRTMDGFDVALAIRKFRGNCWPPLIVALAASTDDTVRDRCQQAGINGLIQKPVTLAALGDELYRVLQNN
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as negative regulator of ethylene signaling.  May delay the transition from the vegetative stage to the floral stage by up-regulating GI (GIGANTEA) and RCN1 and cause starch accumulation in stems by down-regulating the alpha-amylase AMY3D.
What are the official names of this protein?
Ethylene receptor 2, OS-ETR2, OsETRL1, Protein ETYLENE RESPONSE 2-LIKE 1, Os-ERL1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SPNE_ANOGA
Sequence: MEDDDVADFFDFSKPFKRTVVSGGYINGAVKPQKLNIQTLPERAHQGTEYAEKFCREEEARLMEGWVDETLNKSTASRLEQVDDMSSVMEEDTQHLQRVRAKELMEPLFSRYNFTVTPNRLTIHQSKQDILKAIRENPVVVLQGMTGCGKTTQVPQYLLEDAYNRKEWCNIVVTQPRKIAASSIARRVAEERNCALGSLVGFKVGLKEMVSEDTRLTYVTTGVLLNKLITSKSISSYTHIILDEVHEREVDMDFLLIIVRRLLATMRNTKIILMSATIESSEFAQYFKIPGPNSLFAPQLAVSNVTQHDVSVYYLEDLEKLRVDFTIKYEQPDVHEKMYFLAAKVAVVCDRFIDEFESASTIDYKPSIIMFLPGINEIERMAEVLRNFLGDSNVNSQEQTKFTILKLHSMLPSEEQALVFTKPSPGYRKVILSTNIAESSITIPDVKFVIDFCLHRVLVADTLNNFTTLRTQWASRNNCIQRAGRCGRVMNGRVYRLVNKHFFEHGMAQSIEPEMVRCPLSNVVLKTKLLDMGPPHTILALAMSPPNLSDVSNTVLQLKELGALLRTAKGVYDLQDGDITYLGNIMSTLPLDIHLAKLVVLGYVFSVLEEAIVIAAGMNVKNIFCQLRTIEALRVKRHFANGSASDGIAILNAYNWWRSIREQGTGGDTTDWCNRYMLDRKSLIEMAELVQEITMRLKTANIRVVSGANNARWTDRERTVVLKVVMAGAFYPNYFIPTCVTDRELSDKMVYTEIGGRDPFSTVFFCGFDHSNYIGPLYRNEIRALLTERKPTSEKHQVKVEFERSTNKIFVQFQYPPDQQSGKSLYEERNSADRVHPGVYEAIKLRQLRHNQSELLVMHHNDAVAYATEHRLGVWRNHEWHPRSVEIPNAHLSVEPPIHWNRVTATVTHVEHPNKFYLRPHDEKNDNIYHDIMEKLNGCDAVLRAFPEGYAFKQRDIVAAPLPNMVTGKMARAKLLQQCLVRGVEHWTVFFMDFGLTAGVSVKSFRQLRGTPLDMFTKFPDRVFLASLAEVQPSAVRSPKDVWMEETIKHFRQLVHGQQFDVEVYSVVNRVTMVVLRHNPDDPIDLTVNRALINSHHAQLSEESYMSKMNHEKRKRVQFEMELDPMYKTQILNDISEQQRFLEDDDVDSLELPRDLLKVRLMLRGPYSPLEVKCSSTVFSGYRKPVIIEKESLNSVLLDTNPQNTHEKLLVAGCVNETSNSRLIARMTTMMPNIPGLPALMTLIFAPTCLVKKDPDETRVVGLLAGLGTDPRTGESMYPEHDMSLAVDIAIDDDDIADINALRYTMDSILHGGHNEQTPMFGEYSIESLMVKVKDYLIKILQRDRPIQDNRSMAHDFSWVKENPSTSTSSQKRLRSTAIDIYTKAIFPLYHNLNLRPMTADRMEFLRQHCKDLHLLTQSRVPLPKGGITCRLCNVTLESDHTLRIHFYSKLHCDLELKINYRR
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: YSL16_ORYSJ
Sequence: MDRHALGGGGALEIEKTPEAAEDMESEPALAAAREAERVPPWREQVTARGMVAALLIGVVYTVIVMKLSLTTGLIPTLNVSAALLAFLALRGWTHALDRLGIASRPFTRQENTVIQTCAVACYTIGYGGGFGSFLLGLNKKTYELSGASTPGNVPGSYKEPGIGWMTGFLLSTSFVGLLTLLPLRKVLVIDYKLTYPSGTATAVLINGFHTPQGDKNAKKQVRGFLRYFGISFLWSFFQWFYTGGDVCGFLQFPTFGLKAWKHTFFFDFSLTYVGAGMICSHLVNLSLLFGAILSWGIMWPLIGKQKGNWYSAKASESSMSGLFGYKSFICIALLVGDGFYNFVKVIVVTLKSVRERSRRRGLNNRVADADTMAIDDMQRNEVFNRDNIPTWMAYTGYTLLSVIAVVLIPVMFRQVKWYYVIIAYLLAPALGFCNAYGTGLTDMNMGYNYGKIALFIFAAWAGKDDGVVAGLVGCGLVKQLVLISADLMHDFKTGHLTLTSPRSMLVGQVVGTLMGCVVAPLTFFLFYKAFDVGDPNGYWKAPYALIYRNMAIIGVEGFSALPRHCLQLCAGFFAFAVLANLARDFLPRRYGRYMPLPMAMAVPFLVGASFAIDMCAGSLVVFLWHRFDGKRAALLVPAVASGLICGDGIWTFPSSLLALAKVKPPICMKFIPGN
What is the function of this protein?
May be involved in the transport of nicotianamine-chelated metals.
What are the official names of this protein?
Probable metal-nicotianamine transporter YSL16, Protein YELLOW STRIPE LIKE 16, OsYSL16.
What is the protein family that this protein belongs to?
Belongs to the YSL (TC 2.A.67.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTLB_BORBR
Sequence: MRDPLFKGCTRPAMLMGVPATPLAVCSGTIALLGIWFSIAFLALFPVALLAMRIMIRRDDQQFRLIWLYLRMRWLSRDRTHAFWQSTVYAPLRYAERRQRLRKP
What are the official names of this protein?
Type IV secretion system protein PtlB homolog.
What is the protein family that this protein belongs to?
Belongs to the virB3 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CRVP_TRIBI
Sequence: MIVFILLSLAAVLEQSFGNVDFNSESPRRPEKQKEIVDRHNSFRRSVRPTASNMLKMEWYSEAASNAERWAYRCNLGHSPDSSRILDGIKCGENIYMSSNPRAWTEILQLWYDEYKNFVYGVGANPPGSVTGHFSQMVWYKSYRIGCAAAYCPSSGYSYFYVCQYCPIGNIEGSTATPYKSGPTCGDCPSACDNGLCTNPCLREDKFTNCKSLVQQNSCQHDWTRKNCPATCFCHN
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein TRI1, CRVP, Cysteine-rich secretory protein TRI1, CRISP-TRI1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_YERPY
Sequence: MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM21_DICDI
Sequence: MIRNIGSNLMKSSSSILLRNQQQQTNKLLFRNFTSIPEAVAVTSEESYNSKNQFTPIGKDSFAVVHISGKQYKVIEGDIIMTDKIQVDVGEHIVLDKVLLVGTKNETIIGKPIISNFKVHAYIEEQAKTEHVTIFKHKPRKNYKRTTGFQGLATYIRIGGIIKGQETTTTTN
What are the official names of this protein?
Probable 39S ribosomal protein L21, mitochondrial, L21mt, MRP-L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPA1_GLUOX
Sequence: MDIRPAEISDILKQQIASFDQVETVSETGTVLSIGDGIARVYGLTNVMAGEMVEFEGTGLKGMALNLEADNVGVVLFGDGDSIREGDTVLRTKSVVEVPVGKGLLGRVVDGLGNPIDGRGPLTDVEYRRAEVKAPGIMPRQSVSEPMQTGIKAIDALVPIGRGQRELIIGDRQTGKTAILIDTIVAQKPVNAEGDPKKSLYCIYVAVGQKRSTVANLVRTLIEHGAMEYSIVVAATASDAAPMQYLAPYTACAMGEYFRDNGMHALVCYDDLSKQAVAYRQMSLLLRRPPAREAFPGDVFYLHSRLLERAAKMSDANGGGSLTALPVIETQAGDTAAYIPTNVISITDGQIFLETDLFYRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQYREMAAFSQFASDLDAATRKQLDRGARLVELLKQPETSPLPVEEQVVVLYAGTRGYVDPIAVDKVVAYEAALLSELRGAGSDILTAIRNDRQIKPETEGKLKELLEAFGKRFSA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STKLK_ARATH
Sequence: MMRLRRLLERMLRRCCFRDCSVRLTKSLCFKKLIEFDATKNQIVTKLQRLKKKFNNAVKNARKKGQTEDEVEYAKESEKKRFDLSIMIWGSNGVLVAGKSSKKKVAPKEMKPEETDAKVVNEGLSIGREMVPFGSSCGLDESKLTTGWENVEDGAEKREVEEKWKKFKDKLFELLYERSVLMNKTEAMMFKAES
What are the official names of this protein?
Probable transcription factor At4g00130, Storekeeper-like protein At4g00130.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: DDAH_STRCO
Sequence: MPSKKALVRRPSPRLAEGLVTHVEREKVDHGLALEQWDAYVEALGAHGWETLEVDPADDCPDSVFVEDAVVVFRNVALITRPGAESRRAETAGVEEAVARLGCSVNWVWEPGTLDGGDVLKIGDTIYVGRGGRTNAAGVQQLRAAFEPLGARVVAVPVSKVLHLKSAVTALPDGTVIGHIPLTDVPSLFPRFLPVPEESGAHVVLLGGSRLLMAASAPKTAELLADLGHEPVLVDIGEFEKLEGCVTCLSVRLRELYD
What is the function of this protein?
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA).
What are the official names of this protein?
N(G),N(G)-dimethylarginine dimethylaminohydrolase, DDAH, Dimethylarginine dimethylaminohydrolase, Dimethylargininase.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
Protein: PURT_VIBCM
Sequence: MSMFGTATRDNATRVLLLGSGELGKEVAIECQRLGLEVIACDRYADAPAMQVAHRSHVFDMLDADALQQVIDLEKPHFVVPEIEAIATSKLVELEAQGLNVVPTANATRLTMNREGIRRLAAEELGLPTSAYQFADSYESFAAAVETIGLPCVCKPVMSSSGKGQSVIRTPEQIEAAWQYAQQGGRSGAGRVIVEGFVDFDYEITLLTVRAVDGVHFCAPIGHRQEDGDYRESWQPQVMSENAIKAAEYVAEQVVNALGGYGLFGVELFVKGDKVIFNEVSPRPHDTGMVTLISQELSEFALHVRAFTGLPIGQIVQYGPSASAAILGQGQSQNIQFNGLDDALSIPHTQVRLFGKPDIAGRRRLGVALSRGKTTQEATDRAIECAKAVKIHY
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: STTC_ASPTE
Sequence: MYFFRALLSPVVLWPALVSGKSNSNTANYTVEELWDLEVTFWDNFLYPANVKQVEAINSTLFTTEVQGRVDITRVFNGSELNTEYIFGLFSDPNHLSLVGVPIAYSITQFIAERNIASATTVVTFNATSFGNLLLPVTIDTWIMWDANGRIMQYDATFRWFGFLLDTLVEALATSINGTASQATAALTQLLATTVCDTHDKYCTGENQQYDNSTACYDFLTTAIPLGKDYELGRDTLLCREVHEHMVQYDPKMHCPHIGPTGGDYCVNDQTYEQKVLQKYFNVSWIVGVPWTGNIWLGD
What is the function of this protein?
Sesterterpenoid synthase; part of the gene cluster that mediates the biosynthesis of an ophiobolin family sesterterpenoid.
What are the official names of this protein?
Ophiobolin family sesterterpenoid biosynthesis cluster acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the bfoA family.
Protein: LEXA_BACVZ
Sequence: MTKLSKRQLDILRFIKEEVKTKGYPPSVREIGEAVGLASSSTVHGHLARLETKGLIRRDPTKPRAIEVLDEEEVQIPKSQVVNVPVIGKVTAGIPITAVENIDEYFPLPDRMVPPGEHVFMLEIMGESMIDAGIFDKDYVIVKQQNTANNGEIVVAMTEDDEATVKRFYKEDNYVRLQPENPTMEPIILQNVSILGKVIGVFRTVH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ZN835_HUMAN
Sequence: MEGLLSVALQGAELEGNWKHEGQVEDLQENQESCPEPEAVACKGDPAGDSMQERDEFSRIPRTISSPAATQASVPDDSSSRRCSAPGESPKERHPDSRQRERGGGPKKPWKCGDCGKAFSYCSAFILHQRIHTGEKPFACPECGKAFSQSVHLTLHQRTHTGEKPYACHECGKAFSQGSYLASHWRTHTGEKPHRCADCGKAFTRVTHLTQHRRVHTGERPYACAQCAKAFRNRSSLIEHQRIHTGEKPYECSACAKAFRFSSALIRHQRIHTEEKPYRCGQCAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSASLAEHRRIHTGEKPYACGQCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRLVHTGERPYRCLQCGAAFSHVSSLIEHQKIHTGERPYKCGECGKAFSQGSSLALHQRTHTGERPYTCPECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKAFSFSSALIRHQRTHADSSGRLCPAPTPDSTPGLSQGGETCQQGCPGRNPRGPAED
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 835.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DBP10_NEUCR
Sequence: MPRRAASPTPSENEVDIAGALFNNDSDFEDNSSKHHTKKGAVTNSGLDLDFNDLLGNGDDGLPSFNGEGDDDEAFIASLTRSSQRKSSNIQGKSVKKGGGFQAMGLNAHLLRAITRKGFSVPTPIQRKAIPLILERKDVVGMARTGSGKTAAFVIPMIERLKGHSPRVGSRALIMSPSRELALQTLKVVKELGRGTDLKTVLLVGGDSLEEQFGMMASNPDIIIATPGRFLHLKVEMNLSLASIKYVVFDEADRLFEMGFATELTEILHALPPSRQTLLFSATLPSSLVEFARAGLQEPSLVRLDAETKVSPDLESAFFAVKGGEKEGALLHLLHDVIKVPLGPPEGTKEESDELQARKRKREYRPNPKEKPTEYSTIIFTATKHHVEYIANLLKLAGFAVSYVYGSLDQTARLIQVDNFRRGRTHILVVTDVAARGIDMPALANVINYDFPSQPKIFVHRVGRTARAGQRGWAYGLVRQSDVPYLLDLQLFLGRKLIIGHDQKNPSFAADVVVGTLKRDGVDVNIEWVEKALKESADLKALKGVAAKAEKLYMKTRNSASSQSAKRAREVTQSRGWTQLHPLFGEEAAEAQAARDDLLSRINRFKPQETIFELGPKGKSSRNKAAEVVRNMRSRFKERKTTNDEDDEDVDMEDAEGKPDGEETNAFEDFEDEEEEGEAEEAEEAEAKEDPYADDSDSEMEVTVSSSMHTKKKGGPVNFQDPEIFMSYTPRTTSLAEEKAYGVHSGGYSGNSFVEAARDATMDLTNDESAKNFGLPTKSKMRWDKRHSKYVAVANDEDGSKGAKMIRGESGVKIAASFKSGRFDRWRKDNRLGKLPTIGETEKSQLIRNFGAQPGQPRYKHKMEKAPKDADKFRDDYHVRKKRVAEAKEKRIGKYKDGEGSKRELKTATDIRKARAVAEKKREKNARPAKRQKR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp-10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NTPPA_THEKO
Sequence: MLVLASASPRRREILSRFIREFQIIPSSASEECSIADPREHALELARRKAREVYERLGKKATVIGADTVVSIGGKILGKPGNEEEAFRMLKTLSGRMHLVTTGYCIIHRGEEHCGAVVTEVKFRELDEDLIWAYIRTGEPMDKAGAYGIQGKGGLFVEWIRGDYYNVVGFPIEIIWKLKELGFDVLSR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH8_HUMAN
Sequence: MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ
What is the function of this protein?
Does not have a carbonic anhydrase catalytic activity.
What are the official names of this protein?
Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
Protein: LEXA_POLNA
Sequence: MRTFNDFSGLPADRPKLTARQAQILELIRNAIAQTGAPPTRAEIAAELGFRSPNAAEEHLKALAKKGVIELVSGTSRGIRLRTDSLQALNESRISQFSPPVQRLEQLTLPLVGRVAAGSPILAQEHIERTYFFESRLFEQQPDYLLKVRGMSMRDIGIMDGDLLAVKQAREAKNGQIVVARLGDEVTVKRFHRNQHLIELLSENPDFKPIVVQPGEPFELEGLAVGLIRGSLAM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ARP4_KLULA
Sequence: MSNPALQVYGGDEINAIVIDPGSFVTNIGYSGTDCPQSIMPSSYGNVETDGDTKRIFNEQPLLFPRAGMEIKPIVENSTIVDWDRAQEQWEYALNTDLKFESNKGTPVLLTEPIWNSEASRKKSLEILLESMEFEACYLAANSSAVSFAMGRPTCLVVDIGHDVSTVSPVIDGMTLSKSSTRNYVAGKYLNHLIAKNLKPREIVPIFQVLKKKPDFVKRTLSFDVNESVINFANERQFFQEFKETLLHIAPKSLSSFKDELATQTKRSLEAPWGEELIFDADTRYSFAEQLFRPVKEDFPEGWPASTDGIVKTWHNDYVPLKRTKPGTSTNTKEKENTAESTPVPASTEQEAVDSPSQEPNENGKRPVENKEDSSNNEQNSNEIKNEDANSNESSAKATVPSNGIQAKGEDEVAGIVDLINKSMMEADVDLRATLAHNVVLTGGTSKIPGLSDRIMHELNKSLPALKFRMLSSGHLRERQYQGWLGGSILASLGTFHQLWVGREEYEEVGPERLLKDRFR
What is the function of this protein?
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Is required for NuA4 complex integrity.  Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
What are the official names of this protein?
Actin-related protein 4, Actin-like protein ARP4, Actin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FETP_ACIBT
Sequence: MSRQVFCRKYQKEMEGLDFAPFPGAKGQEFFENVSKQAWQEWLQHQTTLINEKRLNVFEPEAKKFLEEQREKFFNNDESVEKAEGWKPE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PSB28_TRIV2
Sequence: MAKIQFSRGLDEEVIPEVRLTRSRTGDTGTATFIFTNPKILDQGTTEDITGMYLIDEEGEIITREVKGKFVNGRPEGVEAVYVMKSAQEWERFIRFMERYAQENDLGFSKS
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: S30LA_XENLA
Sequence: MNGFSTEEDSRDGPPAQAAPFFGQTCCLIDGGERCPRPAGNASFSKRVQKSISQKKLKLDIDKNVRHLYICDFHKNYIQSVRNKRKRKTSDDGGDSPEHETDIPEVDLFQLQVNTLRRYKRYYKLQTRPGLNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKSESSKQLEA
What is the function of this protein?
Functions as transcription repressor, probably via its interaction with histone deacetylase complexes.  Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus.  Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA.  Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import.
What are the official names of this protein?
Histone deacetylase complex subunit SAP30L-A, Sin3 corepressor complex subunit SAP30L-A, Sin3-associated protein p30-like A.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.