PharMolix/UniProtQA huggingface dataset:
Protein: RESF1_HUMAN
Sequence: MNWNEKPKSATLPPLYPKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPISQPLLNIQNYPQQISVSDMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWLNSPMRNPVHSHIGATVSHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLLNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDSSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYLEKRSRSLGSSPVK
What is the function of this protein?
Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1.  Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells.
What are the official names of this protein?
Retroelement silencing factor 1.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes around gamma-tubulin during M phase.
Protein: CH60_RHOMR
Sequence: MAAKQITFNADARMALKRGVDKLADAVKVTLGPKGRNVIIEKKFGAPTVTKDGVTVAKEIELEDKLENVGAQMVKEVASKTSDVAGDGTTTATVLAQAILTAGLKSVTAGANPMDLKRGIDKAVEVVVAELRKMSQEVQDKNRIAQVATISANGDKAIGQLIADAFEKVGKDGVITVEEAKGTETTLEVVEGMQFDRGYLSPYFVTNPDTMEAVLEDAYILIHDKKISAMKDLLPILEKVVQTGRPLLIIAEDVEGEALATLVVNKLRGVLKVAAVKAPGFGDRRKAMLEDIAILTGGTVISEEKGYRLENATLDYLGQAERIIVDKDNTTIVGGKGDPAQIKARANQIRQQIEETTSDYDREKLQERLAKLAGGVAVLKIGAATEPEMKEKKARVEDALHATRAAVEEGIVPGGGVAYIRAIAALDKVEVENEDQKIGVQIVQRALEEPLRQIAANAGWEGSIVVQRVKEGQGDFGFNAQTEEFGNLLEQGVIDPTKVARTALENAASVAGLLLTTEAVVAEKPEKEKAAAPSPGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF_HUMAN
Sequence: METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
What is the function of this protein?
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa.  The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis.  TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
What are the official names of this protein?
Tissue factor, TF, Coagulation factor III, Thromboplastin.
What is the protein family that this protein belongs to?
Belongs to the tissue factor family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: NU3C_LUPLU
Sequence: MFLLYEYDIFWAFLIISSLIPILAFLISGILAPISKGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFIEALIFVLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS15_BOVIN
Sequence: MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKDAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: COX2_BRECS
Sequence: MKEMMMSNMFNDVPTPWAMFFQDSATPNMEGMLELHNNVVFYLCMMLGFVTFMLYNMLTTYNKSVMPYKYLNQGQFMEMMWTTLPAVMLLMIAFPSFILLYMCDEVMAPAMTIKAMGLQWYWKYEYSDFMDEKGDTMEFESYMIPEDLLDEGQLRQLDVDAPIVCPVDTHIRFMVTAADVMHDFSVPSLGLKIDAVPGRLNQMSALMQREGVYYGQCSELCGVMHSSMPMKVEAVPTADFLAWIDEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: END3_BUCBP
Sequence: MEIKKLNHKNRYKILKMFSNIYINFKTGLVFTSNFELLISVMLSAQTTDRMVNKTTQRLFGIANTPSGFISIGLHAIRENIRKLGLYNKKSSNILRTCEILLKRYGGKVPNNREDLESLPGVGRKTANVILNVIFKKKTIAVDTHVFRLCNRIGFAKGTTVLTVEKKLLNIVPEKFKLNFHAWFIMHGRYICTSRVPKCSKCIISSLCEFKDKNI
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: RECX_STAAS
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OE64C_ARATH
Sequence: MASQAANLWVLLGLGLAGILMLTKKLKKTVREDFGAFIDKLMLLPPPQPAPPKAPHPLTGLTFAVSDVFDITGYVTGFGHPDWVRTHEAASSTSPVVSTLVEGGATCVGKTVVDEFAFSISGENKHYDSPTNPAAPTRIPGGACSGAAVAVATNAVDFALGIDTVGGVRVPAGYCGVLGFKSSYGAISNTGIIPVSSSLDSVGWFARDPNTLRRVGHVLLQLPFATQRNPRQIILADDCFQLLKIPVDRITQVVTKSAEKLFGRQLLKHQNLETYFETKVPSLKEFARTKAIANTKVSTSRLLANVMQLLQRHEFLQNHGDWINTVKPAIDPVILSQVCENPELTNEETENLNAIRNETRVAIGSLLKDDGILVIPTLPAVPPKLGSKEITSEDYQNRASSLLSIASISGCCQVTVPLGHHEKCPISVSFIGRHGGDRFLLDTVQTMYPSLQEYSSIVTDPKSSKKAITKEESAEIAKEKGNQAFKEKLWQKAIGLYSEAIKLSDNNATYYSNRAAAYLELGGFLQAEEDCTKAITLDKKNVKAYLRRGTAREMLGDCKGAIEDFRYALVLEPNNKRASLSAERLRKFQ
What is the function of this protein?
Chaperone receptor mediating Hsp90-dependent protein targeting to chloroplasts.  Bi-functional preprotein receptor acting on both sides of the membrane.  Not essential for an efficient import of pre-proteins into plastids.
What are the official names of this protein?
Outer envelope protein 64, chloroplastic, Translocon at the outer membrane of chloroplasts 64-III.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Multi-pass membrane protein.
Protein: 3HIDH_RABIT
Sequence: ASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVF
What are the official names of this protein?
3-hydroxyisobutyrate dehydrogenase, HIBADH.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IKZF5_CHICK
Sequence: MGEKKPEPLDFVKDFQEYLTQQTHHVNMISGSVSGDKEAETLQGAGTEGDQNGLDHPSVEVSLDENSGMLVDGFERTFDGKLKCRYCNYASKGTARLIEHIRIHTGEKPHRCHLCPFASAYERHLEAHMRSHTGEKPYKCELCSFRCSDRSNLSHHRRRKHKMVPIKGTRSSLSSKKMWGVLQKKTSNLGYSRRALINLSPPSMVVHKPDYLNDFTHEIPNIQTEAYESMTKSSQTSGLPRDPQDLMVDNPLNQLSTLAGQLSSLPPENQNERGCSPDVVTCQDEKPFMMQQPATPAVVSSVSASIAQSSSPTSPDPRPAHNQRNYSPVAGPSSDRSAHTSTPSISNSQPSTPAPTLPVQDPQLLHHCQHCDMYFADNILYTIHMGCHGFENPFQCNICGCKCKNKYDFACHFARGQHSQH
What is the function of this protein?
Transcriptional repressor that binds the core 5'GNNTGTNG-3' DNA consensus sequence.
What are the official names of this protein?
Zinc finger protein Pegasus, Ikaros family zinc finger protein 5.
What is the protein family that this protein belongs to?
Belongs to the Ikaros C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIE_MYCLB
Sequence: MQEPHRQPAICLSTRLAKARLYLCTDARRERGDLAQFVNAALAGGVDIVQLRDKGSVGEQQFGPLEARDALAACEIFTDATGRHDALFAVNDRADIARAAGADVLHLGQGDLPPGVARQIVCRQMLIGLSTHDRHQVAAAVAALDAGLVDYFCVGPCWPTPTKPDRPAPGLELVRAAAELAGDKPWFAIGGIDAQRLPDVLHAGARRIVVVRAITAAADPRAAAEQLISTLTATS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: GLYG3_SOYBN
Sequence: MAKLVLSLCFLLFSGCCFAFSFREQPQQNECQIQRLNALKPDNRIESEGGFIETWNPNNKPFQCAGVALSRCTLNRNALRRPSYTNAPQEIYIQQGSGIFGMIFPGCPSTFEEPQQKGQSSRPQDRHQKIYHFREGDLIAVPTGFAYWMYNNEDTPVVAVSLIDTNSFQNQLDQMPRRFYLAGNQEQEFLQYQPQKQQGGTQSQKGKRQQEEENEGGSILSGFAPEFLEHAFVVDRQIVRKLQGENEEEEKGAIVTVKGGLSVISPPTEEQQQRPEEEEKPDCDEKDKHCQSQSRNGIDETICTMRLRHNIGQTSSPDIFNPQAGSITTATSLDFPALSWLKLSAQFGSLRKNAMFVPHYNLNANSIIYALNGRALVQVVNCNGERVFDGELQEGQVLIVPQNFAVAARSQSDNFEYVSFKTNDRPSIGNLAGANSLLNALPEEVIQQTFNLRRQQARQVKNNNPFSFLVPPKESQRRVVA
What is the function of this protein?
Glycinin is the major seed storage protein of soybean (PubMed:2485233).  Glycinin basic peptides (GBPs), and, to a lower extent, glycinin exhibit antibacterial activity against Gram-negative and Gram-positive bacteria (e. g.  L. monocytogenes, B. subtilis, E. coli and S. enteritidis) by forming pores and aggregating in transmembranes, leading to membrane permeability and, eventually, cell death (PubMed:22236762, Ref. 12, PubMed:28590128).
What are the official names of this protein?
Glycinin G3, Glycinin 11S G3, Glycinin A1bB2.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Protein storage vacuole. Note=Hexamers are assembled in the endoplasmic reticulum and later sorted to the protein storage vacuoles.
Protein: YCAM_ECOLI
Sequence: MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWVFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLAQKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVAGIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQYYAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCRTNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLALNVATPFVLVGLGLIFPLLARKANSK
What are the official names of this protein?
Inner membrane transporter YcaM.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_METMJ
Sequence: MEEDTGALPRKENFSEWYNDILWRAEIMDVRYPVKGLYVWYPHGFGIRKRAYGVLRDLMDRDHAETMFPLLIPKTEFMKEAEHIKGFEDEVYWVTHGGRNELDVPLALRPTSETAIYPMYALWIRSHTDLPLRLYQVVNTFRYETKHTRPLIRLREITSFKEAHTVHATREEAAAQVETAIALYREFYDTLRVPVILSRRPAWDKFPGADYTIAADTIMPDGKTLQIGTVHMLGDHFSRTYAITYEDANGEQQYAYQTCYGISERSIAAVVSVHGDDKGLVLPPEVAPLEVVIVPIIVGKRRDEVLASAAALEAELRGAGFAVKLDARDMRPGAKYYHWEMRGVPLRVEVGPRDIDANTVVAVARTGKKTTLDRRGVVEGITSVLAEFGEDLSQAARQAMAARITAAETLEETAEAVKSGVAVVHWCGSQECAEKIEAAVDASIIGSDIRSDLIAVSDGPCVACGGEGTSALVARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEP4_AERHY
Sequence: MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYLTNFL
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRXH2_BRANA
Sequence: MAAEEGQVIGCHEIDVWAVQLDTAKQSNKLIVIDFTASWCPPCRMIAPVFADLAKKFMSSAIFFKVDVDELQNVAQEFGVEAMPTFVLIKDGNVVDKVVGARKEDLHATIAKHTGVATA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes (By similarity).
What are the official names of this protein?
Thioredoxin H-type 2, Trx-H-2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_EXIS2
Sequence: MEYKDTLLMMKTEFLMRGNLPKREPDMQARWNEMNLYEAVQEKNAGKPTFILHDGPPYANGDIHMGHGLNKVLKDIVVRYKSMNGFRSPYVPGWDTHGLPIETALQKAGVDRKSMSVAEFRELCAKYALEQVDHQREQFKRLGVLGDYDNPYITLQPEFEAAQIRLFGDMANKGYIYKGKKPVYWSPSSESALAEAEIEYQDKRSAAIYVAFQVMDGKNILEPTDHFVIWTTTPWTIPANLGISVSGELTYARIEHEGKGYIVAETLVPEVIEALGWEGATIGRVFDGADFEYIKAKHPLYDRESLVMLGDHVTAEATGVVHTAPGHGEDDFRIGQAYGLDVLCPVDDKGVMTAEAPGFEGLFYEDANKEIGVALEEAGALLKLSFIKHSYPHDWRTKKPVIFRATPQWFASIKDFRAEILDEIKEVQWVPEWGETRLHNMFKDRGDWVISRQRAWGVPLPIFYAEDGTEIVTPETIDHIANLFAAHGSNVWYEREAVDLLPEGFTHPASPNGIFKKETDIMDVWFDSGSSHAGVLATRPELERPADLYLEGSDQYRGWFNSSLSTSVATTGKAPYKAVVSHGFVLDGQGRKMSKSIGNTIAPIQIMQQFGAEILRLWVASVDYQSDVRASMDNFKQVSESYRKIRNTVRFLLGNLDQFDHTTHRVAFKDLPESDRFMRTKLDQLVGKVKAAYDAYDFMAVYQLLHNFCVLDLSSFYLDYTKDILYIEKEDAPARRAVQTVMYDTVVTLLQLMAPVLPHTADEAWEFVPGVETASIFLTDLPEAPEMTEEGLALIAKWNSFLVFRDDVLKALEEARAEKLVGKTLEAKLLLAPNDETKALLATIDHLEQLLQVSQIEFVASAEKSYGTTGITVLKADGEKCERCWTYSTELGQDPAHPTLCPRCTEVVNSL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH6_RAT
Sequence: MGTQGKVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTDIKHLDTQELSKFCPMIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNICTEIRLSKTHLASEGTSRITCKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFATGYGAAINSAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVDPRDFEKPIEEVLSDMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRSHLFFSGRILKGSILGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIRCVLLL
What are the official names of this protein?
Alcohol dehydrogenase 6.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_BDEBA
Sequence: MKLSKAKQDLDHHVWKLIKLHSLQDKKILVALSGGTDSVALLRSLTKVHKKNLLGACYFHHGEDSNQEYRKEAQEFCEKLCKKLEIEFYPLRASQLAKSEAEYRELRYEALDRLKKEQGFELVATGHHRDDLLETRLIRLIRGTGAQGFAAMHVLRDGLFRPLLEISKKELKKYLREERLRSFEDPTNKALDPLRNWLREEWLKSLERRARGSTAALARSLETIAQEIENRPWGDLLGQNEAYKTQGLRRSFYLTLSPFEQKRLLAQYLFSLGKRDFSQSHLEEIQKRLDKSQKVITFKVAGCQWEVNAEQIKVQS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_BEUC1
Sequence: MPVALRVVPCLDVDGGRVVKGVNFLDLRDAGDPVELARRYDADGADEITFLDVSASTQGRATTLEMVSATAEQVFVPLTVGGGVRAVADVEALLRAGADKVGVNTAAIARPELLTEIAQHYGNQVLVLSVDARRCPDGVVTDSGFEVTTHGGRTGTGIDAVEWAAEATSRGAGEVLLNSIDADGTTAGFDVEMIEAVRAVVDTPLVASGGAGTVEDFVAAARAGADAVLAASVFHYGTLTISEVKAALRDAGFEVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_AGRFC
Sequence: MSRRHSAEKREINPDPKFGDLVVTKFMNAIMLHGKKSVAESIVYGAFDVVQGKTKQEPLGVFHSALDNVAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLITAARKRNETTMVDRLSGELMDAANNRGSAVKKREDTHKMADANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL6_ALIF1
Sequence: MSRVAKAPVVIPAGVEVKLNGQEITIKGGKGELTRVLNDAVVISQEDNTIVFGPREGVTNAWAQAGTARALVNNMVIGVNEGFTKKLILKGVGYRAAMKGNAVGLTLGFSHPVEHALPEGIKAECPTQTEIVVTGCDKQLVGQVAADLRSYRQPEPYKGKGVRYADEIVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PDXB_ACIBT
Sequence: MKIVADENLAFTDYFFSEFGDIQHKAGRTLTHTDVQDAEALLVRSVTAVNESLIQNTALKYVGSATIGTDHLDIQALEKQGITWANAAGCNAQAVAEYVITALLHLDASLLEQQEKFTLGIVGLGNVGKRLAYMAQLLGWKVIGFDPFVQLDSIENVSFQTLLQQANAVSIHVPLTKKGEHATYHLFDEKAFAALQPNTILINSARGPVVKEAALIEDIQRTQRKVVLDVFEHEPVISEELLNMLALATPHIAGYSLEGKARGTQMIYEAFCQKFGYDINKRFETQLPACEDYFSRHDLKAVLKQKISQIYDIAQDDANIRACVKEGKVEQKAFDLLRKNYPLRREWAAHGGPQA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_THIRO
Sequence: DKIVGPGNIYVATAKRAVFGQVGIDMVAGPSEILVVCDGATDPDWIAMDLFSQAEHDEDAQSILLSWDADFLDRVAASIERLLPSMERETIIATALRGRGAMILARDLDDAIAVANRIAPEHLELSVEDPQAIVGRIRHAGAIFMGRYTAEAIGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSLIMASAAGAAQLAKTASVLARGEGLTAHARSAEYRGAVEPAAEPGLS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.