PharMolix/UniProtQA huggingface dataset:
Protein: MACB_SHIFL
Sequence: MTPLLELKDIRRSYPAGDEQVEVLKGISLNIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDIATLDADALAQLRREHFGFIFQRYHLLPHLTVEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTATGILFGWLPARNAARLDPVDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENDPH_ECOL6
Sequence: MSHDDMSNSSGFNEAAASFSWNGPKKAINPYLDPAEVAPESALSNLITLYAADNEQEQLRREALSEQVWERYFFNESRDPVQREMEQDKLISRAKLAHEQQRFNPDMVILADVNAQPSHISKPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLEHIRDSQLSTSFRFMASHEGLDGLLILPEMSQEQVKRLSTLVAAHMSMCLDAACGDLYATDDVKPEEIRKTWERVAAETLRLDVIPPAFEQLRRKRNRRKPVPYELIPGSLARMLCADWWYRKLWKMRCEWREEQLRAVCLVSKKASPYVSYEAVMHKREQRRKSLEFFRSHELVNEDGDTLDMEDVVNASSSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFHSTLNNGRPNPTWTNATVRQSSDYLVGMFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHWHLLCFMRKKDRRAITALLCKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNIDGRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQAARQQGDKKAGAPVLDNPRLDAILAAADAGCFATYIMKQGGVLVPRKYHLIRTAYEINEEPTAYGDHGIRIYGIWSPIAEGKICTHAVKWKMVRKAVDVQEAVADQGACAPWTRGNNCPLAENLNQQAKDKSADGDTRTDITRMDDKELHDYLHSMSKKERRELAARLRLVKPKRRKDYKQRITDHQRQQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDDKWRNLY
What is the function of this protein?
Possible endonuclease which induces a single-strand cut and initiates DNA replication.
What are the official names of this protein?
Probable replication endonuclease from prophage-like region.
What is the protein family that this protein belongs to?
Belongs to the phage GPA family.
Protein: ATL_STAA8
Sequence: MAKKFNYKLPSMVALTLVGSAVTAHQVQAAETTQDQTTNKNVLDSNKVKATTEQAKAEVKNPTQNISGTQVYQDPAIVQPKTANNKTGNAQVSQKVDTAQVNGDTRANQSATTNNTQPVAKSTSTTAPKTNTNVTNAGYSLVDDEDDNSENQINPELIKSAAKPAALETQYKTAAPKAATTSAPKAKTEATPKVTTFSASAQPRSVAATPKTSLPKYKPQVNSSINDYICKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIVVHDTANDRSTINGEISYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGVGAVGNPRFINVEIVHTHDYASFARSMNNYADYAATQLQYYGLKPDSAEYDGNGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLYDLINEKYLIKMGKVAPWGTQSTTTPTTPSKPTTPSKPSTGKLTVAANNGVAQIKPTNSGLYTTVYDKTGKATNEVQKTFAVSKTATLGNQKFYLVQDYNSGNKFGWVKEGDVVYNTAKSPVNVNQSYSIKPGTKLYTVPWGTSKQVAGSVSGSGNQTFKASKQQQIDKSIYLYGSVNGKSGWVSKAYLVDTAKPTPTPTPKPSTPTTNNKLTVSSLNGVAQINAKNNGLFTTVYDKTGKPTKEVQKTFAVTKEASLGGNKFYLVKDYNSPTLIGWVKQGDVIYNNAKSPVNVMQTYTVKPGTKLYSVPWGTYKQEAGAVSGTGNQTFKATKQQQIDKSIYLFGTVNGKSGWVSKAYLAVPAAPKKAVAQPKTAVKAYTVTKPQTTQTVSKIAQVKPNNTGIRASVYEKTAKNGAKYADRTFYVTKERAHGNETYVLLNNTSHNIPLGWFNVKDLNVQNLGKEVKTTQKYTVNKSNNGLSMVPWGTKNQVILTGNNIAQGTFNATKQVSVGKDVYLYGTINNRTGWVNAKDLTAPTAVKPTTSAAKDYNYTYVIKNGNGYYYVTPNSDTAKYSLKAFNEQPFAVVKEQVINGQTWYYGKLSNGKLAWIKSTDLAKELIKYNQTGMTLNQVAQIQAGLQYKPQVQRVPGKWTDAKFNDVKHAMDTKRLAQDPALKYQFLRLDQPQNISIDKINQFLKGKGVLENQGAAFNKAAQMYGINEVYLISHALLETGNGTSQLAKGADVVNNKVVTNSNTKYHNVFGIAAYDNDPLREGIKYAKQAGWDTVSKAIVGGAKFIGNSYVKAGQNTLYKMRWNPAHPGTHQYATDVDWANINAKIIKGYYDKIGEVGKYFDIPQYK
What is the function of this protein?
Endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure.  One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.  Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells.  Acts as an autolysin in penicillin-induced lysis (By similarity).
What are the official names of this protein?
Bifunctional autolysin.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted, and then anchored on the cell surface at the peripheral cell wall above the completed septum (septal region), for the next cell division cycle.
Protein: Y422_MYCGE
Sequence: MLKKISLFDNLEQWVDLSLLMIRTSFLDANYFGVAKLSLFKYGNYLIDNLNQAQWKTLSQVLQLNKQPYSGFLLVNNHQYLPLQKIKFNLCEEIDLRNKNKWLFPNSFSIFLKQDLSYKKDQNYFNLVNIPKQLKWFLGFNALNDLFRFSILKIENVNQKTSKVINQFFTSKFINSIYFEQVDFEYNNFLTLIEKNERELVDFNCMFFNQLFTFNNKVIKSFFERYYALNEQKNNLKNKLKIAAYEAKSRDNSYFEKLQIERAKQRLFDAKKTFSKQHKNALQLINSFTFSLIFSGWKIKWRSFFNFYRKRILEKKIVSKRIKTRILLLKEIKKMDLLSPKLLVETIDESINLVNKIFANIQNLYQEIISLKSGPNLNWKYQTINQELKIMSARFILTKKEVHEFLIKARLSFIKNFVKQSNNLYVHEKLVNELKENILLNQNHYRGKHNNSFSVLIQKTVFKQFIDTVQYAIGLISMRKSLETFNFAFQIKQYFYESLLANYQKINWQKYELNNLYFVLISLWNSLSKKFQQFFNKYEFLSCGSNDFIWNEGRSEPHFSLLKDKLKNDLNSPKWNFLVDKVINKYLDLNFETPVSFLLASRGFSSTTDTTNKETKNDLKQKLKKCKQKYKLLLKDINLVKWIFRDETNQKLQKIKFIMKRYCILNKTLHLRLKKTNKKIKRTFFIDSEECNINRLEASNKLYLNVLNSQLKTINFFLRSQKNLKKLNFINNINLLINQTKKNGISSWMLFSDLNKINKNESLKLYLLFKLLLNPKLLMINCCNDFTNHAYNFIRGLLISYQNKQGIALIFNDPNNKLVKNFSIKNIDFETGMKK
What are the official names of this protein?
Uncharacterized protein MG422.
Protein: AEGP_HUMAN
Sequence: MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVDNGSRELAWQALSSSAGIWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRDCSPTVTTERDREVSCNFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSALLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP
What is the function of this protein?
Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia.
What are the official names of this protein?
Apical endosomal glycoprotein, MAM domain-containing protein 4.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PFKA_PECAS
Sequence: MIRRIGVLTSGGDAPGMNAAIRGVVRAALSEGLEIYGIYDGYQGLYEDRMEQLDRYSVSDVINRGGTFLGSARFPQFRDEAVRQVCVENMQRRGLDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDVAGTDYTIGYFTALETVLEAIDRLRDTSSSHQRISIVEVMGRHCGDLTLAAAIAGGCEFIVLPEVPFSPEDLVSEIKAGIEKGKKHAIVAITELVCDVDELAKYIEKETGRETRSTVLGHIQRGGSPVAYDRILASRMGAYSIELLQQGYGGRCVGIQNEKMVHHDIVDAIENMKRPFKGDWLETAKKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_RICPR
Sequence: MNNNIINLIAAVVLSLSIIFGWQYFFVKPEQKKQQQRIAMHKSENLNKQKLKALAEPASDIAVQEASQVQRIKIESESLTGSIALKGLRFDDLILKKYKQDLSQNSPAVRLFSPANTENAYFAEIGLVSNLNSVKLPNSNTVWNSDSEVLSPEKPVNLFWINEDGIKFLVTITVDKNYLFTIEQTIINNSDKELPVQSYGLINRKYISLEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSTKFALSKVDWIGITDKYWLSSLIPDKSSRYSSNFNYALKQGTERYQVDFISPVQVIKPGENLSIKSRIFAGAKKVDLLDEYEKSYDIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGISILIVTVIIKLLMFTLANKSYRSMKKMKNLQPEIDRIKNLYNNDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFFGWIKDLSSPDPTTIFNLFGLLPFAPPSFLMIGAWPILMAITMFLHQKMSPELADPIQAQVMKFMPLIFLFMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPC_TRIEI
Sequence: MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKINLMPPPLDFLTTLSTGKTQLAVIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLTDRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARLYGADAVLLIAAILSDQDLKYFIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKKELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: NIKB_STAAR
Sequence: MFIIKSILYRLIQMIVVLFVISTLAFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEPVTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKLSDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVILSQFILPVLTLSLGMCAYIIRLVRSNLLILLKSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIENLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKNKTNTPLISESSDRHA
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Nickel import system permease protein NikB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHLI_ORYSJ
Sequence: MASAFSPATAAPAASPALFSASTSRPLSLTAAAAAVSARIPSRRGFRRGRFTVCNVAAPSATQQEAKAAGAKESQRPVYPFAAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPDIRVVVGDPFNSDPDDPEVMGPEVRERVLEGEKLPVVTAKITMVDLPLGATEDRVCGTIDIEKALTDGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDAELRVKIVEERARFDRDPKAFRESYLEEQDKLQQQISSARSNLGAVQIDHDLRVKISKVCAELNVDGLRGDIVTNRAAKALAALKGRDTVTVEDIATVIPNCLRHRLRKDPLESIDSGLLVVEKFYEVFT
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step.
What are the official names of this protein?
Magnesium-chelatase subunit ChlI, chloroplastic, Mg-chelatase subunit I, Mg-protoporphyrin IX chelatase subunit ChlI, Protein CHLORINA 9.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DHPS_STAAM
Sequence: MTKTKIMGILNVTPDSFSDGGKFNNVETAINRVKAMIDEGADIIDVGGVSTRPGHEMVTLEEELNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDMINDQWAGLYDHRMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIPSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPVERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: DAPA_GEOMG
Sequence: MFKGSIVAIVTPFNNGQVDFEKLRELVEFQISNGTDAIVPCGTTGEASTLDYDEHMDVVKTVIEQVNKRVPVIAGTGSNSTAEAIELSQKAKEVGADGVLLVTPYYNKPTQEGLVRHYTAIADAVAIPQILYNVPGRTGVNMLPETVARLAPHKNIVAIKEATGSLQQASEILALCGDKIDVLCGDDFITFPMMACGAKGVISVLANIMPKTVAELTDAFYAGDMEKARQLHLQTLKIGNAMFIESNPIPVKTALGLMGKCSDEVRLPLCPMGAANKEKLAAIMKEYELI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_BURVG
Sequence: MTYLQESSRPAITVPKLQAMREAGEKIAMLTCYDASFAALLDRAGTDVLLIGDSLGNVLQGHTTTLPVSLDDIAYHTACVARVQPRALVVADLPFGTYGTPAEAFAHSVALMRAGAQMVKLEGGEWLADTIRFLVERSVPVCAHLGLTPQSVHAFGGFKVQGRTEAGAAQLLRDARAIEDAGAQLVVLEAVPTLVAAEVTHMLKIPTIGIGAGLDCSGQVLVLHDMLGIFPGKRPRFVKDFMQGQPSIQAAVEAYVSAVKECTFPGPEHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_TOLAT
Sequence: MENARPIRRALLSVSDKTGIVEFARALQQRGVELLSTGGTARLLADAGLAVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRNTDDAIMTQHGIKPIDLVAVNLYPFAATVANPDCALEDAIENIDIGGPTMVRSAAKNHKDVTIVVNAKDYTRVLAEMDANANSLTYTTRFDLAIAAFEHTAAYDGMIANYFGTKVPTYGVQDEASADSKFPRTINFQFIKKQDMRYGENSHQAAAFYVEADVKEASVSTATQLQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVALGNDILEAYNRAYQTDPTSAFGGIIAFNRELDAATAEAIVSRQFVEVIIAPVVSEEAKAVVAKKANVRLLECGQWQGKANGFDVKRVNGGLLVQDRDQGMVTLTDLKVVTKRQPTEQELKDLLFCWKVGKFVKSNAIVYAKDSMTIGVGAGQMSRVYSAKIAGIKAADEGLEVKGSVMASDAFFPFRDGIDAAAEAGITCVIQPGGSMRDQEVIDAADEHGMAMVFTNMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PRMA_STRZT
Sequence: METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVDRFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTALTEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTGMENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_CLOPE
Sequence: MKDINLIEVEKLIGIEFENKGVLITALTHSSYANQFKDVKYNERLEFLGDSVLQLCVTKYLFNNYKDKSEGELTKIRALVVCENSLHKVSKNLSLGKYIRMSKGEELTGGRERTSIQADALEAVIAAVYLDKGIEVANDFILRNFKDVIDKAINEEIILDFKTRLQEVLQKNGEVNIVYNLVKHEGPPHRRKFFTDLLINNEIMGQGVGFSKKESEQNAAKAALQRLGEIKWEKDTI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_PARXL
Sequence: MAKRDYYEVLGVAKNASDDEIKKAYRKLAMKHHPDRNPGNKDAEGHFKEVKEAYEMLSDSQKRAAYDQYGHAGVDPNMGGAGAQGFGGFADAFGDIFGDIFGQAAGGAARGGGGRAGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEVCHGSGAKPGTKPETCPTCSGSGSVRMSQGFFSIQQTCPKCHGTGTYIPDPCGHCHGAGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPSGDLYVEIHIKQHSVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFTVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTEPQRDLLKQFEKALVEGGSRHSPQSKSWFDRVKSFFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFKI_BACSU
Sequence: MNNERLMLKGIFLGAAAGAALSLLHKPTRQACGMRWLTCKHKLSLYKSNPELLKNTVITKVDEAKKLARTLSKEVDFVNQQVKELKKTTPQVMELVQETKEHFSKK
What are the official names of this protein?
Uncharacterized protein YfkI.
Protein: SUFD_ECOLI
Sequence: MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTRKHENWKYTPLEGLINSQFVSIAGEISPQQRDALALTLDSVRLVFVDGRYVPALSDATEGSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQGVAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKLAFENPLSHHFAHNDLLLAEDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMPVKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNNLLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQIFYLRSRGINQQDAQQMIIYAFAAELTEALRDEGLKQQVLARIGQRLPGGAR
What is the function of this protein?
The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS.  The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress.  May facilitate iron uptake from extracellular iron chelators under iron limitation.  Required for the stability of the FhuF protein.
What are the official names of this protein?
FeS cluster assembly protein SufD.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: GEN_MOUSE
Sequence: MGVNDLWQILEPVKQHIHLQDLSGKTIAVDLSLWVCEAQTVKKMIGTVKKPHLRNLFFRISYLTQMNVKLVFVMEGEPPMLKADVISKRTQTRYGPSGKSRSQKTGRSHFKSVLRECLEMLECLGMPWVQAAGEAEAMCAYLNASGHVDGCLTNDGDAFLYGAQTVYRNFTMNTKDPHVDCYTISSIKSKLGLDRDALVGLAVLLGCDYLPKGVPGVGKEQALKLLQIFKGQSLLQRFNQWIEDPCYSVPQSAPKKVVHCSVCSHPGSPKDHERNGCILCKSDKYCEPHDYDYLCPCEWHQTDHNRHLSEIENNIKKKACSCEGFPFHEVIQEFLLNKNKMLKPITYQRPDLLLFQRFTVQKMEWPSHYACEKLLVLLTRYDMIERKHGRKTSNQLQPIRIVKPRVRNGVHCLEIEWEKPEHYVVEDGDPGKLSLLTMEEASLFEAAYPDAVAVYQKQLSETKGRKQKSMKNKPKGSHLPEADDVINSQSLMTLKPTSKAFPKQNPKINLENSPDPILAQESTSPSLNSFVSPENAPCLNLQEQLVPSPRTLAIKQSKDVSHFLVSECSQPSSSSHDISVITDLQLSTIDWAGTSFSNSPAVQRNTFSQDLASESESSAILPDFEQLSYESEQGTSDSEGSGRDLQQSNPEEQLLSGISALHLHDLPLKERIRIKSSCPQYNVGADAGLESLPLKLKGSCIAYSSSDGSSNFSKDLTGVYLHKESRNSKVLDSRLQENCGANTSLPYSFSDKAVKTSSLQVGLPTAAIPHNPRVAVKTTKNLVMKNSVCLERDSSDEDNAPGSWKSKYTAPEMKHSSQKHSLVHVRDSTHNKLRNPKVESKETKLCNESFKTAEDEENGFSDLGRSPQSFRPCHDKDENSTASWENPLPLRQRLKLRFQNTQSGFYNT
What is the function of this protein?
Endonuclease which resolves Holliday junctions (HJs) by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated.  Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.  Cleaves HJs by a nick and counter-nick mechanism involving dual coordinated incisions that lead to the formation of ligatable nicked duplex products.  Cleavage of the first strand is rate limiting, while second strand cleavage is rapid.  Largely monomeric, dimerizes on the HJ and the first nick occurs upon dimerization at the junction.  Efficiently cleaves both single and double HJs contained within large recombination intermediates.  Exhibits a weak sequence preference for incision between two G residues that reside in a T-rich region of DNA.  Has also endonuclease activity on 5'-flap and replication fork (RF) DNA substrates.
What are the official names of this protein?
Flap endonuclease GEN homolog 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TO20L_HUMAN
Sequence: MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQLWDPTKNKKLQELFLQEVRMGELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPPKVFEMLLHKIPLICQQFEADMNEQDCLEDDPD
What are the official names of this protein?
TOMM20-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: E411_ADE12
Sequence: MKYCLRMAVEGALTELFNIHGLNLQNQCVQIIQQWKNENYLGMVQSGSLMIEEFHDNAFALLLFIEIRAVALLEAVVEHLENRLQFDLAVIFHQHSGGDRCHLRDLRIQILADRLD
What are the official names of this protein?
Probable early E4 11 kDa protein.
Protein: KDGK2_HALVD
Sequence: MTAELVTFGETMIRLSPPEGERIETARSLEFRTAGAESNVAVAASRLGCSAAWLSKLPDSPLGRRVTTELRTHGVEPYVRWDDDARQGAYYIEQGRAPRPTNVIYDRADAAVTTARPDELAVDIVEDAAAFYTSGITPALSETLRETTGELLQTATEAGTTTAFDLNYRSKLWSPSDARDACESLFPKVDVLVAAERDIRAVLELDGDAPTLASELAGDFDFETVVVTRGEDGALARHGGTVYEQPVFETDTVDAIGTGDAFVGAFLSRLIAGEPVETALAYGAATAALKRTVHGDLAVVTPDEVERVLRGGDAGIDR
What is the function of this protein?
Involved in galactose catabolism.  Catalyzes the phosphorylation of 2-keto-3-deoxygalactonate (KDGal) to produce 2-keto-3-deoxy-6-phosphogalactonate (KDPGal).  Can also phosphorylate 2-keto-3-deoxygluconate (KDG) to 2-keto-3-deoxy-6-phosphogluconate (KDPG), but the catalytic efficiency for KDGal is 50-fold higher than for KDG.
What are the official names of this protein?
2-dehydro-3-deoxygalactonokinase, 2-keto-3-deoxygalactonate kinase, KDGal kinase, KDGK-2.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RBBP7_XENLA
Sequence: MANKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTVQWLPDVTRPEGKDYALHWLVLGTHTSDEQNHLVVARVQVPNDDAQFDASHYDSEKGEFGGFGSVSGKIETEIKINHEGEVNRARYMPQNPCIIATKTPSADVLVFDYTKHPSKPDPSGECSPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDISAGPKEGKVVDAKAVFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEEPDIPASELEAQGS
What is the function of this protein?
Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.
What are the official names of this protein?
Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, RBBP-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.