PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_ALCBS
Sequence: MKEHRTRKRFGQHFLHDRNLVDRMIRTLGLQTGDTLVEIGPGRGALTYPLLEELPHLHVVELDRDLIALLRQENTPERLTIHESDALRFDFRTLKPADKPLRVIGNLPYNISTPLIFHLLAQADAISDMTFMLQKEVVERLTASPGTRDWGRLSIMVQYHCQADYLFFVPPEAFSPPPRVDSAVVRLIPHDSPPHPADDEDHLRKLVAQAFTQRRKAIRNGLKSWVSAEQFQAVGIDAGLRPDQLSVADYVALANISRPPADVEDANAPHTEQGKGDNSQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD13_DICDI
Sequence: MATYKPLEYLEHLKKIVPDLSDQINNIKDTYENKLWHQLTKQIEMIIISPQLLEKKELFNFYTNFIRDFENKLRPLSLVEICIAVARQFDTDESRKFIETISQKVKKDKSAYILTLSYIANMNLRSGVAEQLQDCKKTLELAKEELQGVTGLDTIVYSSFYRVSTDYHMAKSQASEFYKNALMYLSYCKLETISQEEQASLAYNLCIAALVGENVYGFGDLIANPILKALEGSQHNWLIAFLKAFNIGDIQQFEGLMSQHRDIISTQTAITNNMQKLRQKISILSLLELAFRTPSDKRSISFSKIAQATKLPLGEIEHLLMKSLSLNLIKGSIDQTVEIIHITWVTPRILDLNQINSMNNRIAEWTEKAKTSLRLVEDDTVDLVA
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit RPN9, 26S proteasome regulatory subunit S11.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S11 family.
Protein: PMGT1_BOVIN
Sequence: MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRIGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT
What is the function of this protein?
Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins.  Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties.  Is specific for alpha linked terminal mannose.
What are the official names of this protein?
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1, POMGnT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: QUEA_PSYCK
Sequence: MTDSEPQTLNNNSEITASHNDDILEYLSVDDYDYELPDQLIARYPLAQRSASKLLYLRANNANSQVEVEDKLFSELPELLNAGDLIVFNDTKVMKARLFGQKDTGGKIEVLIERLVALSDLNSADLDTITSNSDIIDMTVIAEKHIALCHVKASKALKLGQGLVLADGHMTGVMIGRQENLFILAFDTPILPDLELYGELPIPPYFERHADATDNTRYQTVFHDPAKLASVAAPTASLHFDDIVLEKLAAKGIQTAFVTLHVGAGTFAPVKTENLLNHTMHSEYAHLPQATADLINQTHANGKQVIAIGTTVTRVLETAYQQTAVDRQPLSGWAGDTEIFIYPGFEFGVVDKLLTNFHLPKSTLLMLVSAFATKKSIEEAYQHAIESEYRFFSYGDAMLLDKKVD
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR427_MIMIV
Sequence: MFLSKLSIMNDSNSRCDCILSQKPIIFNDFNESITNTEYSGTNPVLNVKSIRKDRNLYRKIAHMNYWLQMVDIKLPDNLDIIETIEFLDNALELKGINQDDLIYKIGDIIVGLKISKKIE
What are the official names of this protein?
Uncharacterized protein R427.
Protein: YIDC1_STRP8
Sequence: MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTFLWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DRS1_AGALE
Sequence: GLWSKIKEAAKAAGKAALNAVTGLVNQGDQPS
What is the function of this protein?
Antimicrobial peptide active against the Gram-negative bacterium E. coli (MIC=8 uM) but inactive against the Gram-positive bacterium S. aureus (PubMed:17561225).  Also inhibits growth of zoospores of the chytrid fungus B. dendrobatidis at high concentrations (above 25 uM) (PubMed:17561225).  Shows anticancer activities since it is cytolytic against HepG2 human hepatoma-derived cells (LC(50)=45 uM) (PubMed:17561225).  Is only weakly hemolytic on human erythrocytes (PubMed:17561225).
What are the official names of this protein?
Dermaseptin-L1, DRS-L1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG3_BACAH
Sequence: MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGKLRRYFDLKNIKDPFLVMKGVMDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLHESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTGSPVREEVLKGNREKALAFLGFSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFEYVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQGYASVLYEEDVTVNSLIKHVEELSHNNEAYNTALKKYNGKEAIQTIIHHISEA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1554_METJA
Sequence: MKIKAVAIFLSLLMIISLFSGCVENEKPIKEGSNDFKLIPVNSKSNFEEFKNTVENSIGNYIYVGHSYASREVQITSTVKSSNVETSTEPERFSKTNVQVKGVDEADILKTNGNIIAFSQNKIYLIKPLPPKYAKIIKNISECGYLYLTNNTLIVISWNKITSYNVSNPEMPKIIWQMDLNGSYVDSRLYNGTLYLVVRKNSIDCPIVWNNYKIGYDKYYIPELPPIYSMDFDTTYIISRINIKSGKVENSIAIVGNYKTTLYMSKNNLYFAYNLKINEKKLMLNFLNESADKYFPTEVADKIKRVIENEDFGDNAKFVEITETIERYLSSLPSEKRHNLMKKLQNDFENYLEEHWEEFEYTGIAKINLDSFEVKSGKVSGHLLNNFAMDEYNGYLRVATTIGDWRFRDKMTNNIYILDSDLNVVGKLTGLEKGERIYAVRFMGDKAYIVTYKETDPLLVIDLKNPKNPKVLGELKIPGYSTYLHPIGNNLFIGIGKDDDGKLKISLFNISDLNNPKEVDKYKLNVWWSPAFRDYHAFLWDEKYKIFFLPAYNHAYVFKVEDNKIEMVKDDEHKTNVLRALFINNYLYTFSLSEMHILDENNWQLVKKIEFENYLPYGYGFK
What are the official names of this protein?
Uncharacterized protein MJ1554.
Protein: TRPA_CHLPD
Sequence: MPENRIARLLKKNKKLLIAYYMPEFPVPGATLPVLEALQKNGADLIELGIAYSDPIGDGPVIQDAAHTAIRNGMSVKKLLDLVRQARKGEGCRKITAPILLMGYCNPLIAYGGDCFLQDAASAGVDGLLLPDLPPEEADDFLERAKGFGLTVVFLVSPVTPPERIEYIDSLSTDFSYCLAVNATTGTAKLSDAGSEAAIDEYLRRVRRHTRKKFVVGFGIKDKARVGHMWELADGAVVGTALLQHIAGAGTPEETARLAGEFWQTLQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PROB_DESHY
Sequence: MSDLRRIVIKVGSSSLNHPEGGLDDQAIQRIAGVIAGIRQLGVECVLVSSGAVAAGVGKLGLKTKPKDMAGKQAVAAVGQGVLIEKYALALEARGLVCAQVLLSRLDLAEASRYRNAQNTLEQLLRYQVIPIINENDTVAVEELCFGDNDRLSALVAGLVHGDLLVILTDVDGLYSANPKLNPQAELIEEVEDLTQVMHIAGGAGSSMGTGGMVTKLKAAEITTRFGMGMFLLHSKRMEEIIELIQGERPLGTYFFPAAHRIMGKKRWIAYGGLSEGSIFIDEGAVKALLKGKSLLASGITGIDGVWERKELVRINNPDGIEVARGLVELSSEELEKVRGKHSEEMLATIPNLEGEEVVHRDNMTLMIE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_PROMH
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKDGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLKPVVDYLKEKLSAPVSLAKDYLNGVDVNAGELVVLENVRFNKGEKKDDETLSKQYAALCDVFVMDAFGTAHRAQASTHGVAKFADIACAGPLLSAELEALGKALDKPERPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAEGHSVGRSLYEADLVDDAKKLMEKCDIPVPTDVRVATEFSETAPAVLKSANDIKDDEQVLDIGDVTAERLAEILKNAKTILWNGPVGVFEFPNFRKGTEVIAKAIADSDAFSIAGGGDTLAAIDLFDIADKISYISTGGGAFLEFVEGKKLPAVAMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MZRA_RAHSY
Sequence: MNRRLLKRSFIWPLLLMLLAAATMIGLAVSRLPAPTSALQIRPARAGVALPDGFYVYQRLSQRGIHIKSITPLNDALVVQLDTASQRKLAETVLQDILPAGFVIQYYEPQHATAWGAKLDRERLKFG
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARLY_DINSH
Sequence: MSDTKSNAMWGGRFAAGPDAIMEAINASIGFDRRLARQDIDGSRAHAAMLAQQGILSSKDAEAIREGLLTVLSEIETGQFAFSAALEDIHMNVEARLKELIGEPAGRLHTGRSRNDQVATDFKLWVRDQLDAADAGLLALLRALLAQAEAGADWVMPGFTHLQTAQPVTWGHHMMAYVEMFARDRGRMQDARARMNECPLGAAALAGTSFPLDRDATAQALGFDRPAANSLDAVSDRDFALEFLAAASICAMHLSRMAEELVIWSSAQFRFVTLSDRFSTGSSIMPQKKNPDAAELIRAKIGRIVGANVALLTVMKGLPLAYSKDMQEDKEQVFDAADTLMLALAAMEGMVRDMTANRASLEDAAASGFSTATDLADWLVRELNLPFRDAHHVTGTLVAMAEAKGCDLPDLSLAEMQSVHGAIRADVFEVLGVHNSVASRTSYGGTAPSQVRAQVARWKERLG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDP1L_ARATH
Sequence: MDISNEAGVDAFSIIGPTTIIGRTIAVRILFCNSVSIFRHKVFRILKFFLRGGRVLLSPFVSLLHPRNPQGILVMVTTMAFLLNRYTSLKAKAEMAYRRKFWRNMMRAALTYEEWSHAAKMLDKETPKVNETDLFDVELVSNKLDELKHRRHEGSLRDIIFCMRADLVRNLGNMCNPELHKGRLHVPRLIKEYIDEVSTQLRMVCDMDTEELSLEEKLSFMHETRHAYGRTALLLSGGASLGAFHLGVVKTLVEHKLLPRIIAGSSVGSVMCAVVGTRSWPELQSFFEGSWHALQFFDQMGGIFTTVKRVMTQGAVHEIRHLQWKLRNLTNNLTFQEAYDITGRILGITVCSLRKHEPPRCLNYLTSPHVVIWSAVTASCAFPGLFEAQELMAKDRTGEIVPYHPPFNLDPEEGSASVRRWRDGSLEMDLPMIQLKELFNVNHFIVSQANPHIAPFLRMKEFVRACGGRFAAKLAQLAEMEVKHRCNQVLELGLPLREVASLFAQEWEGDVTIVMPATFSQYLKIIQNPSNVEIQKAANQGRRCTWEKLAVIKANFGIELALDECVTVLNHMRRLKRSAERAAAFSAISSSPPSKHLLAGTNRFNASKRIPSWNCIARQNSSGSVDDDVLAEASRLYQHIVVGSGRNSNRTSNLSHTYDAGSECDSPEAEDWTRSGGPLMRTNSAQMFTDYVQNLDAVDPEQIRASENDSIVAASSSSHSITVTEGDYLQTGRTHNGFVLNLVRGENLRMNSEPEDSQNESEIPETPESVQLDSPEKDIIDGESSASEDGDAQANLIHDHE
What is the function of this protein?
May be involved in the release of fatty acids from the oil body in germinating seedlings.  Can hydrolyze triacylglycerols in vitro.
What are the official names of this protein?
Triacylglycerol lipase SDP1L, Protein SDP1-LIKE.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Associates with the oil body membrane.
Protein: BIP3_MAIZE
Sequence: MDRVRGSAFLLGVLLAGSLFAFSVAKEETKKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAAVNPERTIFDVKRLIGRKFQDKEVQRDMKLVPYKIINKDGKPYIQVKIKDGENKVFSPEEISAMILGKMKDTAEAYLGKKINDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLIKKKYSKDISKDNRALGKLRREAERAKRALSNQHQVRVEIESLFDGTDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKSQIHEIVLVGGSTRIPKVQQLLKDYFNGKEPNKGVNPDEAVAFGAAVQGSILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSMTKDCRLLGKFDLNGIPSAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNEKGRLSQEEIDRMVREAEEFAEEDKKVKERIDARNQLETYVYNMKNTVGDKDKLADKLEAEEKEKVEEALKEALEWLDDNQSAEKEDYEEKLKEVEAVCNPIVSAVYQRSGGAPGGDADGGVDDDHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein 3, BiP3.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ATPG_BURM1
Sequence: MAGMKEIRGKIKSVQNTRKITKAMEMVAASKMRRAQERMRAARPYADKVRAIAAHMSRANPEYRHPFMVANEGAKTAGIILVTTDKGLCGGLNTNVLRASVQKFKELEEKGQKVEATAIGGKGLGFLNRFGAKVLSQVVHLGDTPHLDKLIGAVKTQLDLYSEGKLSAVYLAYTRFINTMKQEAVIEQLLPLSSEHFEADDGTPATSWDYIYEPDAQAVVDELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKTVISELQLVYNKSRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPFC_STAEQ
Sequence: MTKTIGLLVMAYGTPYKESDIEPYYTDIRRGKKPTEEELQDLKDRYEFIGGLSPLAGTTDRQAEALLEALNKEQDDVNFKLYLGLKHISPYIEEAVEQMHNDGIKEAVTVVLAPHYSSFSVGSYDQRAQEKADEYGIQLTHIKHYYQQPKFIKYWTEKINETLEQIPNQEHDETVLVVSAHSLPKGLIERNNDPYPHELHETAEILKQESNIIHVAEGWQSEGNTGTPWLGPDVQDLTRDLYKEHQFKHFIYTPVGFVCEHLEVLYDNDYECKVVCDDIGVNYYRPEMPNTHPLFIGAIVDEIQSHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_SYNE7
Sequence: MTSAITEQLLKAKKAKGITFTELEQLLGRDEVWIASVFYRQSTASPEEAEKLLTALGLDLALADELTTPPVKGCLEPVIPTDPLIYRFYEIMQVYGLPLKDVIQEKFGDGIMSAIDFTLDVDKVEDPKGDRVKVTMCGKFLAYKKW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: RL5_SYNWW
Sequence: MARLYETYKKDIVPKMMEKFQYDNIMQVPKVERVVVNIGVGEAIQNPKALDGAVNDLSIISGQKPVITRARKSIAGFKLREGMAIGCKVTLRGERMYDFLDRLINLALPRVRDFRGVSPQAFDGRGNYSLGIKEQTIFPEIDYDKIDKIRGLEVVVVTTAKTDEEARELLKSMGMPFR
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DXS_SPHAL
Sequence: MTDRPHTPLLDTVDVPADLRKLKPEDLRQFADELRAEMISAVGTTGGHLGSGLGVVELTTAIHYVFDTPRDKLVWDVGHQCYPHKIITGRRDRIRTLRQGGGLSGFTKRSESEYDPFGAAHSSTSISAALGFAIANKLKDEPGRAIAVIGDGSMSAGMAYEAMNNAKQAGNRLIVILNDNDMSIAPPVGGLSAYLAKLVSSRPFLELREIARRFARKLPEPLHKAAKKTDEYARGMAMGGTLFEELGFYYVGPIDGHNLDHLIPILENVRDSDHGPVLIHAVTKKGKGYAPAEAAADKYHGVQKFDVITGEQAKAPPGPPAYQNVFGETLAKLAETDKRIVAITAAMPSGTGVDKFAKVHPDRSFDVGIAEQHAVTFAAGLAAQGMRPFAAIYSTFLQRAYDQVVHDVAIQNLPVRFAIDRAGLVGADGSTHAGSFDITYLATLPNMVVMAAADEAELVHMTYTAAEHDAGPIAFRYPRGNGTGVALPAVPQKLEIGKGRVVREGKTVAILSLGTRLAEALKAADTLEARGLSTSVIDLRFAKPLDEELIRRTLAAHEVCVTVEEGSIGGLGAHVLTLASDEGLIDAGLKLRTLRLPDMFQDQDKPELQYDAAGLNAPQIVDTVLKALRHNSAGVEEAGVRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CLC4A_HUMAN
Sequence: MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL
What is the function of this protein?
(Microbial infection) Involved in the interaction between HIV-1 virus and dendritic cells.  Enhances HIV-1 binding/entry and virus infection.  Requires ITIM motif-associated signal transduction pathway involving phosphatases PTPN6 and PTPN11, SYK, Src kinases and MAP kinases.
What are the official names of this protein?
C-type lectin domain family 4 member A, C-type lectin DDB27, C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor.
Protein: TRI5_FUSPO
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPYAAMMNYFNDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTLDFFEGCWIEQYNFGGFPGSHDYPQFLRRMNGLGHCVGASLWPKEQFDERSLFLEITSAIAQMENWMVWVNDLMSFYKEFDDERDQISLVKNYVVSDEISLHEALEKLTQDTLHSSKQMVAVFSDKDPQVMVTIECFMHGYVTWHLCDHRYRLNEISEKVKEQKTEDAQKFCKFYEQAANVGAVSPSEWAYPPVAQLANVRSKDVKNVKQIEKPLLSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: RHG20_HUMAN
Sequence: MEAMSPQQETLGGQPGRSSSLTGVSRLAGGSCTKKKMKTLAERRRSAPSLILDKALQKRPTTRDSPSASVDTCTFLSSLVCSNRTLLIDGRAELKRGLQRQERHLFLFNDLFVVAKIKYNNNFKIKNKIKLTDMWTASCVDEVGEGNTNAMKSFVLGWPTVNFVATFSSPEQKDKWLSLLQRYINLEKEKDYPKSIPLKIFAKDIGNCAYSKTITVMNSDTANEVINMSLPMLGITGSERDYQLWVNSGKEEAPYPLIGHEYPYGIKMSHLRDSALLTPGSKDSTTPFNLQEPFLMEQLPREMQCQFILKPSRLAAAQQLSDSGHKTFKRRRSIINWAFWRGSSTHLDNLPSSPTSPMPGQLFGISLPNICENDNLPKPVLDMLFFLNQKGPLTKGIFRQSANVKSCRELKEKLNSGVEVHLDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLLDQLPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPASSSPELENEFTKKVSLLIQFLIENCLRIFGEEITSLFREVSVRCDTRENASDISCFQLNDSSYDSLENELNEDVDAPCSDLVKKLGQGSRSMDSVLTLSDYDLDQPEVEGLLTLSDFDLAHSKDEDVQMKRPLESKPVNILVYTKIPLRDHARAPSAMCTPSYLSTAAANAAKSLRRHRRCSEPSIDYLDSKLSYLREFYQKKLRKSSCDAILSQKDEDYLKQNQPLQEEGKTCFKQSLVTGTDVSKKNATTQNTKKKSLSGSEGNHVKLFPKSKPVAISVASYSPMSSQDHSKNQPFDVNTSGYSPPHTADALKGPRTHRRCSEPNIEDQNRKLTYLRGIYSKKQHKTSCEAGLLHGEEDYLKRHKSLQMEGQKLINQSLVMGIEVGKSSATNQNTEKVLPPRLNLCPRTSYSSLSSPGTSPSGSSVSSQDSAFSQISEHSVFTPTETSSPIDCTFQAQRKREDLSPDFSNASHVSGMPGPSSGQACSRPAYTKKDTMEWHSQMHSVTLHPSTWLRNGVASLKNWSLKKKAKAARPEEEKIASPKGPLEPPPHASGVPEANSLQEEQKDLPLRAAEGLSPVQSAQRCSSSPFQDSERHCSSPFSLVESRLKLCMKSHEEIEPGSQSSSGSLPWERASASSWTLEDATSPDSGPTVVCDIEDRYLTKDI
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 20, Rho-type GTPase-activating protein 20.
Protein: PO6F1_MOUSE
Sequence: MPGISSQILTNAQGQVIGALPWVVNSASVATPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPQPVAVRKPNTPESPAKSEVQPIQPTQAVPQPAVILTSPTPALKPSAATPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLMEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP
What is the function of this protein?
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
What are the official names of this protein?
POU domain, class 6, transcription factor 1, Octamer-binding transcription factor EMB, Transcription regulatory protein MCP-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1_LACGA
Sequence: MAKEDVIEVEGKVVDTLPNAMFKVELENGATILAHVSGKIRMHYIRILPGDRVTVELSPYDLTKGRITYRFIK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLMN_SHEEP
Sequence: APQAPSVENPPEADCMLGIGKGYRGKKATTVAGVPCQEWAAQEPHRHGIFTPETNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLFDYCDIPQCESSFDCGKPKVEPKKCPARVVGGCVATPHSWPWQVSLRRRSREHFCGGTLISPEWVLTAAHCLDSILGPSFYTVILGAHYEMAREASVQEIPVSRLFLEPSRADIALLKLSSPAVITDEVIPACLPSPNYVVADKTVCYITGWGETQGTFGVGRLKEARLPVIENKVCNRYEYLNGRVKSTELCAGDLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSTYVPWIEETMRRY
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation.  In ovulation, weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.  Also cleaves fibrin, thrombospondin and von Willebrand factor.  Its role in tissue remodeling and tumor invasion may be modulated by CSPG4.  Binds to cells (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).