PharMolix/UniProtQA huggingface dataset:
Protein: OPGD_ECO27
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDLSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKNQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PRSW_HALH5
Sequence: MFSLLTAAIAPAMALLCFFYLKNEYGSQTLGFVVRTFLIGALLMFPVMVLQHAFLAEGFFANPLLKAFILYGFFEEFFKWFMLYFFAYKHVEFNRRYDGIIFGVSLSLGFASMENGLYLIANGVETALGRALLPVSSHAIYGVIMGYYLGRAKMEEKHRKKWLVLSLFLPVLLHSLYDAILLLWSKHFLFVMVPFMLVLWWVAIQKVKLANQLDR
What is the function of this protein?
Involved in the degradation of specific anti-sigma factors.  Responsible for Site-1 cleavage of the RsiW anti-sigma factor.  This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
Protease PrsW, Protease responsible for activating sigma-W.
What is the protein family that this protein belongs to?
Belongs to the protease PrsW family.
Protein: DAPB_LACLA
Sequence: MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIGFDADIWLDLTAPEAAYKNTRFALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTAVKTAELMSEERLAHHQGAVDEKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALGIRKVMTVSELKYGLEHFLDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_HELHP
Sequence: MVNDIIADSLTRIRNASMRRLEVTTLYYAKIVVSIVEVFKTKGFIKDYKVNDKDGKRSIMVQLAYDEQGKSAINEIKRISKPGRRVYKARSELKRFKNGYGTIVVSTSKGVVANDEAYKANVGGEALCSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DGTL1_BRUA4
Sequence: MSLEGIGFGYRERAPYACDPARSRGRLVPEPESPTRTPFQRDRDRIIHSTAFRRLKHKTQVFIAHEGDHYRTRLTHTIEVAQIARALARALRLDEDLAEAVALVHDFGHTPFGHTGEEALNDRMKAFGGFDHNAQSLRIVTKLEHRYADFDGLNLSWETLEGLVKHNGPLLGAHAAHPDAAVPLPILDFNERYDLELTRFASLEAQCAAIADDIAYNAHDIDDGLRAGLLSLDALDEVPLTKRLLDLVRTRYPDLDPVRTGHELVRRQITIMVEDVIEEAQRRLAAAKPQSVEDVHGQSHALVAFSDTMRTDEKVLKRFLFKNLYFHDSVVVRRHAADKILQDLFDTCFANPSIMPSEWQSGCETLDEAARARRVADYLAGMTDNYAVREHRRLFDHTPDLA
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: KGUA_MYCTU
Sequence: MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLLVGTAPGSP
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_STRT1
Sequence: MGQKVHPIGLRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFIQKELADASVSTIEIVRAVNKVIVSLHTAKPGMVIGKGGSNVDALRAQLNKLTGKQVHINIVEIKKPDLDAHLVGETIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TYSY_BPPHT
Sequence: MTQFDKQYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVMSKQMRFDNSEVPILTTKKVAWKTAIKELLWIWQLKSNDVTELNKMGVHIWDQWKQEDGTIGHAYGFQLGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDDLDAMALTPCVYETQWYVKQGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYNFTVDDFKLINYKHGDKLLFEVAV
What is the function of this protein?
Provides the sole de novo source of dTMP for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: SN25A_DANRE
Sequence: MAEDSDMRNELADMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKDAEKNLNDLGKFCGLCSCPCNKMKSGASKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTDDARENEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
What is the function of this protein?
May play an important role in the synaptic function of specific neuronal systems.  Associates with proteins involved in vesicle docking and membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 25-A, SNAP-25A, Synaptosome-associated protein 25.1, SNAP-25.1.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Synapse, synaptosome. Cell membrane. Note=Complexed with macromolecular elements of the nerve terminal.
Protein: COBA1_BOVIN
Sequence: YDYCEHYSPXCDSSAPEAAQAQEPPVDEYAPEDIMEYDYEYGEAEYKEAESVTETPTVTEETIAQTEANIVDDFQEYNYGTESYQTEAPRSVSGSNEPNPVEEVFTEEYLTGEDYDSQRKNSEDMLYENKQIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPTNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLIEGPPGPAGPAGLMGPPGLQGPTGPPGDPGERGPPGRPGLPGADGLPGPPGTMLVLPFRYGGDSSKGPTVSAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGEMGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGEDGIRGEDGEIGPRGLPGEAGPRGLLGPRGTPGPIGQPGIAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGSLGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQVGPRGEDGPEGPKGRAGPTGDPGPPGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGVSGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKE
What is the function of this protein?
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
What are the official names of this protein?
Collagen alpha-1(XI) chain.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TIG_CORDI
Sequence: MKSSVEKLSETRVKLNVEVPFEELKPEIDQAYKALAQQITIPGFRRGKAPRQLIDARIGRGAVLEQVINDMLPTRYQQVVEENELVVLGQPHIDITKLEDNEVVEFTAEVDVRPEITVPDFSAFAVEVPALKSNDEAIDAQIDKLRERFGELKDTKRKLKTDDFAIIDIEAAIDGEKLEEATTEGMSYQVGAGDLIDGLDTALRGLKAGESAEFTTTLKAGEHEGKEAAVTVTVQQTKERKLPELDEEFVQTASEFDTVEELRESIAEQVAEQAKAEQATAIRDEVLKAALAEATFELPEGVVEDQIHAQLHQLLNQVGGDEAALNAALEAQGTSREQFDADNRKNSEEAVRTQLFLDALAEQEQPEVSQQELTDHILFTAQSYGMDPNQFITQLQQSGQIGNLFSDVRRGKALAAAICRVSVKDDEGKAVDPSEYFGEEEESAEESE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PF4V_HUMAN
Sequence: MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
What is the function of this protein?
Inhibitor of angiogenesis.  Inhibitor of endothelial cell chemotaxis (in vitro).
What are the official names of this protein?
Platelet factor 4 variant, C-X-C motif chemokine 4 variant, CXCL4L1, PF4alt, PF4var1.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS2_STAEQ
Sequence: MRQKTLDVLEFEKIKSFVADETISDLGREKVQEMAPASNFDTVEFQMNETDEISQIYNKHRLPSLSGLAKVSPLVHRASIGGVLNVAELNRIKRLVQVQNQFKTFYNQMLEEDEEVKYPILHDKMNHLPILTDLFKEINETCDAHDLFDHASYTLQSIRSKISRTNQRIRQNLDRIVKNQGNQKKLSDAIVTVRNDRNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPNSVVEMNNQISRLRNDEAVERERILTELTGFVSAEADALLIAESVMGQIDFLIAKARYARTIKGTKPTFKEDRTIYLPNAFHPLLDKDTVVANTIEFIDDVETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSIFENVYCDIGDEQSIEQSLSTFSSHMKNIVEILQDADQNSLILFDELGAGTDPSEGAALAMSILDYVRRLGSLVMATTHYPELKAYSYNREGVMNASVEFDVETLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEQEINAMIESLEQNSKRVDQQRIELDRLVREAQQTHDALSKQYQQYQNYETSLMDEAKEKANQRVKSATKEADEILKELRNLRDHKGAEVKEHELIDKKKQLDDQYEVKSIKQHVQKKKYDTIHTGDEVKVLSYGQKGEVLELVGDEEAVVQMGIIKMKLPIEDLEKTKKKKEKPTKMVTRQNRQTIKTELDLRGYRYEEALNELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVRQFRGGMPSEGGFGVTVAELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: ATAS_ASPTN
Sequence: MAKQELMNLFLSKEFASGYKLAELVTGPFAQLLVDYSGVVQSTQRPLVILDNACGTGIISEALNRSLDSQTKGHWELTCGDISDSLVQYVNQRIQDEGWPRAKAQLVDAQDTKLPSSHFTHIFAAFECLRILQPGGTVAISNWQLPEWLVIAKSAVEAMPGDLPFPTVKEFLASLNEGWDSEEPTRVKLEQEGFDMVQVATVSQKLSLPKSTLVELIKPMLPVILGRFWTDEQRAKHEKHIPTALQQYLDDKYGASDDVPVEPRVIIATARKPC
What is the function of this protein?
Acetylaranotin bis-thiomethyltransferase involved in the biosynthesis of acetylaranotin derivatives, members of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide-bridged cyclic dipeptide (PubMed:30096370).  The first step of acetylaranotin biosynthesis is performed by the NRPS ataP which produces diketopiperazine cyclo-L-Phe-L-Phe via the condensation of 2 phenylalanines (L-Phe) (PubMed:23586797).  The ataC domain of ataTC then catalyzes the formation of bishydroxylation of cyclo-L-Phe-L-Phe (PubMed:23586797).  The glutathione S-transferase domain ataG in ataIMG further catalyzes the conjugation of two glutathiones to the bishydroxylated intermediate (PubMed:23586797).  Next, the dipeptidase ataJ removes the Glu residues (PubMed:23586797).  The following step is performed by the carbon sulfur lyase domain ataI of ataIMG which may convert the bis-cysteinyl adduct to yield an epidithiol intermediate (PubMed:23586797).  The ataT domain from ataTC then catalyzes the oxidation of the free dithiols, followed by a cyclization step catalyzed by the cytochrome P450 ataF (PubMed:23586797).  AtaF probably acts as an epoxidase to promote a dual epoxidation formation at C8 and C9 along with C8' and C9', followed by the spontaneous nucleophilic attack of the amide nitrogens N10 and N10' to yield an intermediate with the pyrrolidine partial structure (PubMed:23586797).  The final steps of acetylaranotin biosynthesis involve the acetylation and ring rearrangement of an epitetrathiodiketopiperazine intermediate to produce acetylaranotin (PubMed:23586797).  AtaH probably catalyzes the acetylation of epitetrathiodiketopiperazine to produce a diacetate and ataY is responsible for the formation of the dihydrooxepin moiety that converts the diacetate intermediate to acetylaranotin via acetylapoaranotin (PubMed:23586797).  Both enzymes could function independently in the absence of the other (PubMed:23586797).  The acetylaranotin bis-thiomethyltransferase ataS located outside of acetylaranotin gene cluster is the main thiomethyltransferase responsible for converting acetylaranotin and its related intermediates to their methylated forms (PubMed:30096370).
What are the official names of this protein?
Acetylaranotin bis-thiomethyltransferase, Acetylaranotin biosynthesis protein S.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: ARS_PSEVC
Sequence: MQKISIIFNLFLSLGCLAFTFNGSASETKNEWITLGTMAGPIPNAKHSQPANAMLVNGNTYVVDAGDGTAGQLAKVGLDIKNVDAVFLSHLHFDHTGGLPAILSLRWQTSARNELVVYGPPGTQQTVDGIFEYMTYGTLGHYGVPGQVPAPANTNIKVVEVEDGTQLKLPDFTVDVIRNSHYSWPKGSEEWKKFQALSFKFSLQDYTVVYTGDTGPSSAVEKLSSGVDLLVSEMMDIDHTVNMIKETNPQMPKGKFIGIHKHLSKHHLSPKQVGELAKAANVGSLVITHMAPGLDTQAEIDFYTKQVASEYKGPISVAQDLNRYELKR
What is the function of this protein?
May function as a glycosulphohydrolase involved with desulfation of sulfated polysaccharides.
What are the official names of this protein?
Arylsulfatase, AS, Aryl-sulfate sulphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AtsA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS5_ALIB4
Sequence: MAVNREDFQEAIVKIGRVTKVVKGGRRFRFTALVVVGDKNGTVGFGTGKAKEVPDAIKKALDDAFKSLVTVSIKGTTIAHDIEHKYNASKILLRPASEGTGLIAGGAARPVLELSGVKDIIAKSLGSNNPNNLVQATVEALAKIKG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GAL7_SALTY
Sequence: MTPFNPIDHPHRRYNPLTGQWVLVSPHRAKRPWQGAQETPSQQMLPAHDPDCFLCAGNTRVTGDKNPDYKGTYVFTNDFAALMADTPDAPDSHDPLMRCQSARGTSRVICFSPDHSKTLPELSLPALTEIVRTWQTQTAELGKTYPWVQVFENKGAAMGCSNPHPHGQVWANSFLPNEAEREDRLQKAYFAEQRSPMLVDYVQRELADGSRTVVETEHWLAVVPYWAAWPFETLLLPKTHVLRITDLSDEQRDSLALALKKLTSRYDNLFQCSFPYSMGWHGAPFNGEENAHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAERLRAVSDIHFRESGV
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: SAE2_ARATH
Sequence: MATQQQQSAIKGAKVLMVGAGGIGCELLKTLALSGFEDIHIIDMDTIEVSNLNRQFLFRRSHVGQSKAKVARDAVLRFRPNINIRSYHANVKNPEFDVDFFKQFDVVLNGLDNLDARRHVNRLCLAADVPLVESGTTGFLGQVTVHIKGKTECYECQTKPAPKTYPVCTITSTPTKFVHCIVWAKDLLFAKLFGDKNQDNDLNVRSNNSASSSKETEDVFERSEDEDIEQYGRKIYDHVFGSNIEAALSNEETWKNRRRPRPIYSKDVLPESLTQQNGSTQNCSVTDGDLMVSAMPSLGLKNPQELWGLTQNSLVFIEALKLFFAKRKKEIGHLTFDKDDQLAVEFVTAAANIRAESFGIPLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLKKDVDKFRMTYCLEHPSKKLLLMPIEPYEPNPACYVCSETPLVLEINTRKSKLRDLVDKIVKTKLGMNLPLIMHGNSLLYEVGDDLDDIMVANYNANLEKYLSELPSPILNGSILTVEDLQQELSCKINVKHRFFSEILNPVLNSVWFLIILPSTFPKLFHFTESRNQDGLSLDIILGFSNVTIRRVLTMFETGRRLTHPLLILFCHREEFDEEKEPEGMVLSGWTPSPATNGESASTSNNENPVDVTESSSGSEPASKKRRLSETEASNHKKETENVESEDDDIMEVENPMMVSKKKIRVE
What is the function of this protein?
The dimeric enzyme acts as an E1 ligase for SUMO1 and SUMO2.  It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.
What are the official names of this protein?
SUMO-activating enzyme subunit 2, Protein EMBRYO DEFECTIVE 2764, Ubiquitin-like 1-activating enzyme E1B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_LACLS
Sequence: MNLQEMNARKEKIRNFSIIAHIDHGKSTLADRILEQTETVSKREMQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPEMVRQEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPQGEVDAPLKALIFDSVYDAYRGVILQIRVIDGSVKVGDRIQLMSNGKEFDVTEVGIFTPKAVARDFLMAGDVGYVAAAIKTVADTRVGDTVTLASNPATEALEGYKEMNPMVFAGIYPIESNKFNDLREALEKLQLNDASLRFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFGIDLIMTAPSVVYHINTTDGETLEVANPSEFPDPTRIENIEEPFVKAQIMVPNDFVGPVMELAQRKRGIFLTMDYLDANRVNIIYHIPLSEIVFDFFDKLKSSTKGYASFDYEISDYRPSNLVKMDILLNAEKVDALSFIVHKDFAFERGKVIVEKLKKLIPRQQFEVPIQATIGNKIVARSDIKALRKNVLAKCYGGDISRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FTSZ_CAUVN
Sequence: MAISLSAPRTTELKPRIVVFGVGGAGGNAVNNMIEAGLEGVEFVVANTDAQQLQFAKTDRRIQLGVQITQGLGAGAHPEVGMSAAEESFPEIGEHLDGAHMVFITAGMGGGTGTGAAPIIAKCARERGILTVGVVTKPFHFEGRHRMRLADSGIQELQRYVDTLIVIPNQNLFRVANERTTFAEAFGMADQVLHSGVRSITDLMVLPGLINLDFADVRTVMTEMGKAMMGTGEGTGEDRALMAAQNAIANPLLDEVSLKGAKAVLVNVTGGMDMTLLEVDEAANAISDQVDPEANIIFGAAFDPSLEGVIRVSVVATGMDGASIAQIEPKPVSRNISAAPLIAETSRPAPQPEPARPTARYEAARPAERPVAFAPEPAPEPEIVMSAPQPEPEAELYYDEPTVAEEPRVSAAPARSVNRIVDPLVDDVAEEPLFPENNYYEERRPQKQGGFFSMFGGGRQRYEQQASAPQAQARSAQSARPQLQPIETPQADDAEDLEIPSFLRRLAN
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: RP41L_ARATH
Sequence: MAAKPGAATPTYSPKIVGRSRLPIFKDSDLDWSRPDGRGFHQCRPALLQTGAVSSASGSAYAEFGNTKVIVSVFGPRESKKAMVYSDVGRLNCNVSYTNFASPTLGQGTDHKEYSSMLHKALEGVIMMETFPKTTVDVFALVLESGGSDLSVLISCASLALADAGIMMYDLITAVSVSCIGKSLMIDPVTEEEGCEDGSFMMTCMPSRYEITQLTITGEWTTPNINEAMQLCLDASSKLGEIMRDCLKQSASASDE
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events.  In vitro, is a processive phosphorolytic exonuclease and requires a single-stranded poly(A) tail on the substrate RNA for its activity (By similarity).  Plays an important role in seed germination and early seedling growth by mediating specific cytoplasmic mRNA decay of transcripts coding for the abscisic acid (ABA) biosynthetic enzymes NCED5 and NCED6, and the ABA signaling transcription factors ABI3 and ABI4 (PubMed:23132787).
What are the official names of this protein?
Exosome complex component RRP41-like, Protein SLOWER GROWTH, Ribosomal RNA-processing protein 41-like.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DXR_HELPJ
Sequence: MVVLGSTGSIGKNALKIAKKFGVKIEALSCGKNIALINEQIKVFKPKKVAILDPNDLNNLEPLGAEVFVGLDGIDAMIEECVSNLVINAIVGVAGLKASFKSLQRNKKLALANKESLVSAGHLLDISQITPVDSEHFGLWALLQNKTLKPKSLIISASGGAFRDTPLDLIAIQNAQNALKHPNWSMGDKITIDSASMVNKLFEILETYWLFGASLKIDALIERSSIVHALVEFEDNSVIAHLASADMQLPISYAINPKLASLSASIKPLDLYALSAIKFEPISVERYTLWRYKDLLLENPKLGVVLNASNEVAMKKFLNQEIAFGGFIQIISQALELYAKKSFKLSSLDEVLALDKEVRERFGSVARV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: FPG_COREF
Sequence: MPELPEVEVVRRGLEEHMVGRTIVSAAVVHPRTARNQAGGGAEIEANLTGLRVGATNRRGKFLWLELDDVAQQAPSGLGLLVHLGMSGQMLVKSPDATLNPHLRARAELDDGNEVWFVDQRTFGYWWLGELVDGVPGRVSHIARDLLDDALDIPALAAVLKTKNTEIKRLLLNQEIVSGIGNIYADEMLWEAGIHPRQKASRISLTRLVALLEAGREVMTRALDQGGTSFDALYVNVNGASGYFSLSLNAYGQAGKPCARCGTPIARETFMNRGSHFCNRCQKVR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL10_AROAE
Sequence: MGLNLDDKKAVVAEVSAQVANAQTIAVAEYRGIAVGDLTGLRAKARESGVYLRVLKNTLVRRAIAETPFAGLSDQLVGPLIYGISEDPVAAAKVLNDFAKGNDKLVLKAGSYAGNTLDKAGVQALASIPSREELLARLLGVMQAPVTGFACTLAALAKKREEEVAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.