PharMolix/UniProtQA huggingface dataset:
Protein: CD3D_MOUSE
Sequence: MEHSGILASLILIAVLPQGSPFKIQVTEYEDKVFVTCNTSVMHLDGTVEGWFAKNKTLNLGKGVLDPRGIYLCNGTEQLAKVVSSVQVHYRMCQNCVELDSGTMAGVIFIDLIATLLLALGVYCFAGHETGRPSGAAEVQALLKNEQLYQPLRDREDTQYSRLGGNWPRNKKS
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.  In addition of this role of signal transduction in T-cell activation, CD3D plays an essential role in thymocyte differentiation.  Indeed, participates in correct intracellular TCR-CD3 complex assembly and surface expression.  In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly (PubMed:10935641).  Interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ESR1_ANOCA
Sequence: YEVGMMKGGIRKDRRGGRMLKHKRQREENDSRNAGALTEARSTALWPSPLMIKHSKKNSPALSLTADQMVSALLEAEPPVVYSEYDPSRPFNEASVMTLLTNLADRELVHMINWAKRVPGFVDLALHDQVHLLECAWLEILMVGLVWRSMEHPGKLLFAPNLLLDRSHGKVVEGFVEIFDMLLAASSRFRMMNVRGEEFVCLKSIILLNPGIYTYLSSTLKSVEERDHIHRVLDKITDTLMHLMAKSGLSLQQQHRRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPAAKGSPPSEDDPLNQLAVPSPSMHSLLPCYVNKQEEGNEQEAI
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DJC15_PONAB
Sequence: MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQGLVRSLIAVGLGVAAFAFAGRYAFRIWKPLEQVITETAKKISTPSLSSYYKGGFEKKMSRREAGLILGVSPSAGKAKIRTAHRRVMILNHPDKGGSPYVAAKINEAKDLLETTTKH
What is the function of this protein?
Negative regulator of the mitochondrial respiratory chain.  Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP.  Acts as an import component of the TIM23 translocase complex.  Stimulates the ATPase activity of HSPA9 (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 15.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HORM1_RAT
Sequence: MATMQLRRTASMSALVFPNKISTEQQSLMFVKRLLAVSVSCITYLRGIFPERAYGTRYLDDLCVKILKEDKNCPGSSQLVKWMLGCYDALQKKYLRMIILAVYTNPEDPQTISECYQFKFKYTKNGPIMDFISKNQNNKSSTTSADTKKASILLIRKIYVLMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDGDCEGVIFDGDPTYLNVGEVPTPFHTFRLKVTTEKERMENIDSAILTPKDSKIPFQKILMDKDDVEDENHNNFDIKTKMNEQNENSGTSEIKEPNLDCKEEEIMQFKKNQSSSISQCQVEQLISKTSELDVSESKTRSGKIFQCKMVNGNQQGQISKENRKRSLRQSGKTVLHILESSSQESVLKRRRVSEPNEHT
What is the function of this protein?
Plays a key role in meiotic progression.  Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends.  Promotes synaptonemal-complex formation independently of its role in homology search.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
What are the official names of this protein?
HORMA domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser- 375 is restricted to unsynapsed chromosomal regions (By similarity).
Protein: RK6_SPIOL
Sequence: MSLPLPSHMKSVFLGMKVEISTSVPVTRIGFWRKSVDCKESRIGKQPITVPANVAIAMEGQDLKVKGPLGELSITYPREVLVEKQESGFLRVRKAVETRRANQMHGLFRTLTDNMVVGVSKGFEKKLQLVGVGYRATVEGKDLILSLGFSHPVRMAIPDELQVKVEENTKVTVSGRDKSVVGQFAATIRSWRPPEPYKGKGVRYVDEVVRRKEGKAGKKK
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L6, chloroplastic, Chloroplastic large ribosomal subunit protein uL6c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOC2A_DICDI
Sequence: MSNQFKILLFAKVKEVIGKDSIFIDLPLDESTSFNLIRKLKHIYPQISSTLEVSLLAVNQEYISRDQDIKINSNDEIAIIPPVSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by mocs3.  After interaction with mocs2l, the sulfur is then transferred to precursor Z to form molybdopterin (By similarity).
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARE1_MYCTO
Sequence: MSSRYLLSPAAQAHLEEIWDCTYDRWGVDQAEQYLRELQHAIDRAAANPRIGRACDEIRPGYRKLSAGSHTLFYRVTGEGTIDVVRVLHQRMDVDRNL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 (By similarity).
What are the official names of this protein?
Toxin ParE1.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: EIF3L_DROME
Sequence: MYGGDEYATNSDYYDDYAHTGDPQLDMEYERNYYAARMPDNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNINI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOL_HUMAN
Sequence: MASTPMGNEGEKKSSWPSQAAPSLRGGPASLSRSEEYLSQISAELMEEALCTACCHLNPVPIKKKQSQDQATQISKRAFFTKT
What are the official names of this protein?
Putative protein T-ENOL, CDIP transferase opposite strand, pseudogene, CDIPT antisense RNA 1.
Protein: RUVB_LISMF
Sequence: MDERIISSETVDAEEVSFETSLRPQNLSQYIGQDKVKNNLTVFIEAATLRNEALDHVLLYGPPGLGKTTLAMVIAAEMGSQIKTTSGPAIERPGDLATILTSLEPGDVLFIDEIHRLSRAIEEILYPAMEDYCLDIVIGTGPTARSVRLDLPPFTLIGATTRAGLLSAPLRDRFGVIDHLEFYTEEQLTEIVLRTSNILDTKIDDLGAREIARRSRGTPRIANRLLKRVRDFAQVRGNGTVTEKLAKEALTLLQVDPRGLDTIDQKLLHTIIQSFRGGPVGLDTIAASIGEERETIEDMQEPYLLQIGFLQRTPRGRIATETAYNHLGISYEKEV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CAS6L_PYRFU
Sequence: MRIEIKLLPLQDNPVIPFNYNYELYSQIVEKAGAIEPRIVKLLESPHGYWTFSRIIIRKREIIPEKGIKILSDDISLYISSSNKEIIKGIVEGIEKSPEFKIGDVGFLVADIKALKSKEIKNVNIFSTLSPIVVRTVKFEGDKLKHWDLYPHDELFLDRLRKVMLLRYHEVMGDLPEDKDFRIELIKFKPTRLIVKDSYIRGSLMVFRYYGSKEIAKFGYENGFGEKTNLGFGMVKIIEEQ
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism (Potential).
What are the official names of this protein?
Putative CRISPR-associated endoribonuclease-like protein Cas6.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Protein: YIDD_MYCBO
Sequence: MSLSRQSCGRVVRVTGRASARGLIFVIQVYRHMLSPLRPASCRFVPTCSQYAVDALTEYGLLRGSWLTMIRLAKCGPWHRGGWDPIPEGLTTGRSCQTDVDGANDDWNPASKRGERESFV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TFCP2_CHICK
Sequence: MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPENENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKIGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPSKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITYVNNAPSPGFNSSHSSFSIGEGNGSPNHQPEPPPPIADNLLPTSTPQEAQQWLHRNRFSTFSRLFRNFSGADLLKLTREDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESQQLQELQQKHEDGDAVTSTFFVYHAIYLEELTAVELTEKLAQLFSISSQQISQIYKQGPTGIHVLISDEMIQNFQDESCFVLDTMKAETNDSYHIILK
What is the function of this protein?
Binds the B-response element 5'-CAAGTCCAGGCAAGT-3' of the ENS1/ERNI promoter.  May be the major transcription activator thus being essential for its expression.
What are the official names of this protein?
Transcription factor CP2.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. CP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_CROS5
Sequence: MQFIDRAEIEVEGGKGGDGIVAFRREKYVPAGGPAGGNGGKGGSVVLKAEENLQTLLDFRYARRFKADDGKRGGPNNCTGAMGKDTIVEVPCGTVVYDLETEEILGDLVKNGQTLCVAQGGKGGLGNKHFLSNQNRAPEYALPGLEGEHRNLRLELKLLAEVGIIGLPNAGKSTLIASLSAARPKIADYPFTTLVPNLGVVRKPTGDGTVFADIPGLIAGAHEGIGLGHEFLRHIERTRLLLHLVDVTSADPIADYEVIQQELTAYGRGLSDRPQIIALNKVDACDQDTLDLIAEELQQLSQSEIFTISAVTKTGVEELLQAIWHRLDQATSNHQDSSLPLV
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENLYS_BPT7
Sequence: MARVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDEMAVGSHAKGYNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGAVLRAHHEVAPKACPSFDLKRWWEKNELVTSDRG
What is the function of this protein?
Endolysin with amidase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and breaking down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, N-acetylmuramoyl-L-alanine amidase, T7 endolysin.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: POXI_PENO1
Sequence: MSTVYYPSVILKKSPLPLKLTPARASGNFGTPITAALQRASFNITIITRTESSSTFPAGLPIIRTSYTLENLTTALAGQDAAICVVGPGGIGAQVLMIEAAEAAGVKRFIVDDFGWGPGFRNLPEFRAIHAHRRAGWELAKAKAQANPNFTFTGITSGNPIDWAMKRFPLMGFDIARCSAIIYDSGTEKFTATTLAGIGQSVVGVLQHPDETANRFVKVLSIITNQNELLEAFQRVTGRQWPVQRASAQTLIESGQQKFQAGMGGWVLELVVAQMYDEGEARCVMAPSWEASDSPLLGVKKESADEVVAKVLQL
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Oxidoreductase poxI, Oxaleimides biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: DESC_ASPDE
Sequence: MGALSEIFTAGYVALAGITGFFLVFLGFLVVISDYIDGWRSRRALGDIPIVDEGSNLSPILRWNSQPYDAEAEFTRAYYKYSKNGKPFAARIQHGGYAIVLPPSACRKVRSIGHEQLSFLDALAEFADLSLHMDVTSRRVIEATHACNNETTIKNFQERLALECGKHLAPVFDPPQEQESTELKTLKSVFAAISAVATALILGPDCPEALVSEVTAGATAYNEVMIQCRILRAQYPKILKPLVWRFSRTARELRAILSRLKARLVPEIKRRIAYLEAHSTSENQAESAGSFSLLDILIQTSFKNRHLPSTPVENDKWADLLCQQALLYHFKLSRAPGTSVTFMLYRVMNHPEYATMLRDEMIAALKPSGGNWTADILQRAPKLESFNKETFRMHDISNFVGLRVAMRPVDLRSVSPPLHLKPGTMIMTPSRTVHYDAEHYVDPLTFNGLRFYDATSNTCTPRVFTTSPTYLPFSHGTGSCPARNFATQIARMLFIRLLMGYEFELANEEMPAYGLMDGTAYFPNPEVRMRVRVRGK
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin desertorin (PubMed:26389790).  The non-reducing polyketide synthase desS first catalyzes the formation of the pentaketidic 4,7-dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules (PubMed:26389790).  Further O-methylation by desB leads to the formation of 7-demethylsiderin (PubMed:26389790).  Then, an oxidative phenol coupling catalyzed by the cytochrome P450 monooxygenase desC forms the 6,8'-dimer M-desertorin A via dimerization the monomeric precursor, 7-demethylsiderin (PubMed:26389790).  M-desertorin A is further converted to M-desertorin C (PubMed:26389790).
What are the official names of this protein?
Bicoumarin synthase desC, Cytochrome P450 monooxygenase desC, Desertorin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: 5NT3A_MOUSE
Sequence: MDRAAVARVGAVASASVCAVVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYNGKRCPTCHNIIDNCKLVTDECRRKLLQLKEQYYAIEVDPVLTVEEKFPYMVEWYTKSHGLLIEQGIPKAKLKEIVADSDVMLKEGYENFFGKLQQHGIPVFIFSAGIGDVLEEVIRQAGVYHSNVKVVSNFMDFDENGVLKGFKGELIHVFNKHDGALKNTDYFSQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVKEESLEVVNSILQKTL
What is the function of this protein?
Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP).  CMP seems to be the preferred substrate.
What are the official names of this protein?
Cytosolic 5'-nucleotidase 3A, 7-methylguanosine phosphate-specific 5'-nucleotidase, 7-methylguanosine nucleotidase, Cytosolic 5'-nucleotidase 3, Cytosolic 5'-nucleotidase III, cN-III, Lupin, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I.
What is the protein family that this protein belongs to?
Belongs to the pyrimidine 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_OSTTA
Sequence: MAVPKRRQSNAQSGMRAATWKRKALDAARNALSLGKSLTTRKSTGFYYPPAPVSENWDDEAKGFGKDLDAAE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCH4_STAA9
Sequence: MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RS8_BACCR
Sequence: MVMTDPIADMLTRIRNANMVRHEKLEVPASKIKKEIAELLKREGFIRDVEYIEDNKQGILRIFLKYGANNERVITGLKRISKPGLRVYAKADEVPRVLNGLGIALVSTSKGVMTDKDARQLQTGGEVVAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS15_STAS1
Sequence: MAISQERKNELIKEYRTHEADTGSPEVQIAVLTAEITALNEHLREHKKDHHSRRGLLKMVGRRRHLLNYLRDKDVQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TILS_LEGPL
Sequence: MTRPLLSPEWVARLKQFKKLIVGFSGGLDSTVLLHVLASTPPLYNQLLAVHINHGISGNSLNWQRHCEQLCLDLGIAFIAKAIEFDRSANVEEAARNARYDFFSSLLEDNDCLVLGHHLDDQAETVLLQLFRGAGVDGLAAMQECSNLGAGQLARPFLTCPRVELEHYARIHELKWIEDESNQDTKYSRNYLRHRVMPLLLEKWPGVAGNISRAATHCQQAKANLEVLAIKDCPDLLNATDHLLIEPLKGLEFERITNVLKFWLKKNRVQLPSSKTFQRIIHEIIFAKLDAMPTVSWNQIQVRRFQQHLYLLKADQINLPKAIKWQQFPASLTYPDANIELSAVKAQKGLMIPKDAQIEIRFRKGGEEIYWHDQTKHLKKLFQEWQIPPWLRERVPLVYINDQLACVVGYAVSDLFFTTNPLEAWSIVNNS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.