PharMolix/UniProtQA huggingface dataset:
Protein: ATG9_ASPFU
Sequence: MMTSNILSRFLPPNGSPSVYETIRNHDATSDSSDVEERAGLTLEDGPGEHYSDRELEDAMADAGRSRLLDRDDAFISRRSPRKASVAGPSKSNSRRRHFSRPRWAHDASPSHDFEDGDDDVPASLLVEGHHDDDELKSRLPPPPTSHITPDDRQPSRPGPSTRGVRGRGRAAKEQQPLHHADRRRAPAVRWSLGQPNLNTVDPKEKAMWMWANVENLDNFLKEVYTYFLGNGIWSILLNRVLSLLTFAFVVGFSTFLTNCIDYHKVRGSKSLNDILIKQCTTKMSLSSTFLLWLLTLFWIGKAFQCLLDIRRLKHMHDFYYYLLGVSDTDIQTISWQEIVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNKQLFSRTLEWNINLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASIVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGLVPEETTVFDPEYALLEVINYTHYAPSHWKGRLHSDEVRREFTELYQMKIVIFLEEILSMIFTPFILWFNLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVINQGDRRDPARQDLRADYFSTKDGKMLASYYGFLDNYGANHRGSHPATRRQFYPPPAFPTLGSPPAGEMGTIGDRLDQTQTRHGLAGPFMGQQSVFGPSRYGLTGLGDHASPAPSILLDPHHQPSTSGFRGTSRAAGVQRYRSSRAHPPISGTIADGDESPVATGRSDPSRPAANAAGASSAGGVGTSDSNLGDSWRMNLVEDGDDDNTEGGENVDAIAGGAGVLGLIQQFQRVNKDSRGRTAVGL
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CIAO1_MALGO
Sequence: MSQQNTVEGGFDLSSGVSDKKEWVFNLQEVIPTGHKRTVRSVAWSPNGEVLATASFDSTVGLWERIPENIRAEEGSDGPEWECFGTLEGHDSECKSVAFSYNGNLLASCGRDKSVWVWEAQPDADYECIGVLIEHSQDVKCVIWHPKEEILASASYDNTIKMYVDDPSCDWYCYTTLQAHSSTVWSLSFSPCGQFLASSSDDMTIWIWRRVSAAECVELGIQAHGNTPGRSGERWVPTYCIQGHFSGPIFSVNWAPGDSFDPRQALGKLVAAGADGKIIVFFLVRIYATLRGTYACAQSLEDNNPSRIFVHVGAQEENAHGSVDVNCVKWAPMNTDGSAPTMIASAGDDGEIRIWT
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: MODC_YERPA
Sequence: MLELNFSQQLGDLHLQVATDLPAQGITAIFGLSGAGKTSLINVIGGLTRPQQGRVILNGRVLVDAEKNIYLPPEKRRVGYVFQDARLFPHYRVRGNLQYGMAASMRGQFDAIVGLLGIEPLLNRFPFTLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAQDVNTPILYVSHSMDEILRLADQVVVMDAGKVRAVGGLEEVWASSALRPWLQREEPSSILRVSVIGHHDRYAMTALALGDQRLWVGKLDAAEGNSMRIRINAADVSLALQPPHSSSIRNILPVKVAECLDVDGQVDVKLAIGEQWLWARITPWARDELGLKPGQWVYAQIKSVSFNRQNGPVPD
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYP_STRE4
Sequence: MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRTNLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATSEYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVGNDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLANAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFKLGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTSG1_MOUSE
Sequence: MVSRPAMSPVSPVWPRKPNLWAFWVLRLVLLLSLKSWAEDTLQHCTWLLVLNKFEKVGLHLSKDRFQDHEPIDTVAKVFQKLTDSPIDPSENYLSFPYYLQINFSCPGQNSEELARKGHLMGMKPMVRINYMYSVNFYRWEMENLQILMEAAPMRSTGYCPAEAMCILNWYTPMPFKNGSVVSSVDIYTNGIGPFIPKKRFYVNMNGFLKRDASGKSLFAIGYESLVLKSSHFRLSKSRPLWYTVNHAPVFILGGFYDEKAILFSDSNFQDYVLLELSIDSCWVGSFYCPILGFSATIHDAIATESTLFIRQNQLVYYFTGTYSTLFDKSHGSSRWVRVLPSECIKRLCPVYFSGNGSEYVLALTTGKNEGYIHIGTITDGLVSFEMVPDGWSVCEKLPGKNCSIDWATYITDERNLLLLVKIDSGQFYLVNFNTEFKTLNILYKIPEFIPEAKELDFLVLLDTVTYTNTPMTPKGLFFNTLNNMLYIWGNFILQSYNREEFIFLADFPKESTIKYMVNSFKGQMAVVTENEEIWYFLEGGYDVYQVVPSQGWRTYLKLQKMQKSPLYSTNESLVSLFYQDENLFQLVYLFDVGKERLVKRLLPVGTLMEYNLPKPFTVVNQGNYKMITFTNTCPFKAIHAVDVPKKQHASRTESYVALPPLVSESLGFHNNNTLAVYQGLVYYLLWLHSKYDKPYADPVHDPTWRWWQHKTKDKDYFFYLFSNRLAAEGIYINMNAYQKLYNMSGDYGIPDLFFLDKGNWFTFTVVLLSHQDTFTSSDSQGPTINVDKKLSLSLVLADPECLSVTATREFLLNRNTLLTKIKVIDKKRCSEQGMVGRNIKKTSMLIKVLGAPGNCIQRTYLGDHIQGIRLVPIFIGCPPGKRLAFDVSYTIKHSEEINKHYFDCVIKDAEMPCFLFRDLFQPFFLVQDLVTGDSGSFLGSYVLKVVGGGRTLNTIRDYTEEEIFRYNSPLDTTNSLIWKTKVERTTEDKKFYIMSHESPGVEWLCLENSPCYDIIPQSIYPPEFFFKLLVSNRGVDNSTYCDYKLTFIVHIHGLPLSSKRSSFIVMVSTSFFIALVVFYILFCLVWPHIVKAWVSFRWKIHNMMAPETYSSSSSSGGFTLHSHSSEGSFEGPSRPGTKEDNVQAKRAKVA
What are the official names of this protein?
Cation channel sperm-associated protein subunit gamma 1.
What is the protein family that this protein belongs to?
Belongs to the CATSPERG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: VP74_NPVCF
Sequence: MAVLTAVDLTNASRYAAHMHRLEFIGRWRERLPHILIDYTLRPASSEDDYYVPPKLRDRALAVKLAFSRRGCDSMSCYPFHETGVVSNQTEFAYTQTSETSVAYSQPACYHLDRAAAMREGAENEVQSAEFTYTPNNQCVLVDSTSKMYFNSPYLRTEEHTIMGVDDVPAFNVRPDPDPLFPERFKGEFNEAYCRRFGRDLMNGGCSFRWWESLIGFVLGDTIYVTFKMMANNIFSELRDFDYTAPSPLLPARPVADSNAVLAQWRAVRDRAVDWNFEKQFSEAPTLQQLGLLADNGGLMQLAYTAETGFAKTPIAYSARVTPRAVRDFGAPGRQLNDEELEAIIASFLEEYSLVFGIATDIGFDMLLTAFKTMLKKINTALIPALKRMLVSTSQRVTVRLLGETYKAAIVHSMNRIAIKTLTTAAKALTRIAIKASSVVGIVLILFTLADLVLALWDPFGYSNMFPREFPDDLSRTFLTAYFETLDANSSREIIEFLPEFFSDVVETDDDATFQSLFHLLDYVAALEVNSDGQMLHFTESNAIEDFDEATLVGQALASSSLYTRLEFMQYTFRQNTLLEMNKNNNRFNGAIASLFLTGTAVALAAFMLHKKLTFFVYFAIFLMLALYYLVKEPYEYFKTIDLLF
What is the function of this protein?
Essential for virulence of baculovirus occlusion bodies for insect larvae.
What are the official names of this protein?
Protein p74.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p74 family.
Protein: NUOB2_NITMU
Sequence: MSTNGVMEKGFVTTSLDSVINWGRTGSMWPMTFGLACCAVEMMQAGASRYDLDRFGIVFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGIIQLQNKIHRTNTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BCHB_RHOP5
Sequence: MQLTVWTYEGPPHVGAMRVATGMEGLHYVLHAPQGDTYADLLFTMIERRDRRPPVTYTTFAARDLGKDTAELFKTAAQNAYDRFKPQAMIVGASCTGSLIQDDPGGLAKALALPIPVVAIDLPAYQRKENWGAAETFYQLVRAIAGPKAPPPGSKRPERPAGKRPSCNLLGPTALGFRHRDDIIELTTLLGKLGIDVNVTAPMGATPADLARLGEADFNVVMYPETASQAASWLHRMFHQPFTKIVPIGVSATREFIEEVAKLADVDPTAVLKSYSSRLPWYSHSVDSTYLTGKRVFIFGDATHVVAAARMASDEMGFKVVGLGTYSREFGREIREAAKLYDVEPLITDDYLEVEAKVAELHPELVLGTQMERHIAKRLGVPCAVISAPVHVQDFPARYAPQMGFEGANVIFDTWVHPLMMGLEEHLLTMFRDDFEFKDGATPSHLGVGHAPAPAPAVADSAAVEVLDATTATTTETTTAVWAADAEKELRKIPFFVRGKARRNTERFANENGVATITVETLYDAKAHFSR
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: FLOT4_MEDTR
Sequence: MYKVAKASQYLVITGIGIKDIKLAKKAWILPGQSYSVFDLSPVNYTFEVQAMSAEKLPFVLPAVFTIGPRVDDKESLLKYAKLISPHDKLSNHVKELVQGIIEGETRVLAASMTMEEVFRGTKEFKQEVFGKVQLELNQFGLLIYNANVKQLVDVPGHEYFSYLGQKTQMEAANQARVDVSEAKMKGEIGSKLREGQTLQNAAKIDAETKIIAMQRAGEGDKEGIKVRTEVKVFENQREAEVAEANSELAKKKAAWTKAAQVAEVEAAKAVALRDAELQGEVERMNALTTTEKLKAEFLSKASVQYETKVQEANWELYKKQKEAEAILYEKKAEAEAQKALADATFYARTQAAEAELYAKKKEAEGIVTLGNAQGVYLSALLNALGNNYTAVRDFLMINGGMFQEIAKINAEAVRGLEPKISIWTNGGDNSGGEGAMKEVAGVYKMLPPLFKTVHEQTGMLPPAWMGVLPDKNLN
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles (By similarity).  Required for normal infection threads initiation and elongation and nodulation.  Probably involved in polar growth of the infection thread.
What are the official names of this protein?
Flotillin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Membrane, caveola. Cell membrane. Note=In puncta evenly distributed in the cell membrane of root hair and epidermal cells. Accumulates in the tips of elongating root hairs and localizes to the infection thread membranes upon inoculation with bacteria.
Protein: YUAO_ECOLI
Sequence: MCFFLGSRLAYAENIDGSSTISNRDISGSLNIGINKDANIDINGTVNIKDYFSVATCNGQSSTCPEGGLNASAKIDKSASVGASVTIVGDSSKGELNIDGGSTLYTQQLWVSGNDNDKTSNVSDDSNGSLSINNGSNVFVVSSQDDTPFKTNSVKWNQNIISQGNNITDGTVSSGDLVLGKTGNGIIDIDNNSKLDVKNDVVVSTGVDGIPNEKPSEINIKNESNFSVHGDMKGGISAAGKLNLNMDNSSNLHVDKNIAVGIGRESNITVSASRESSIFSDGNFTVATGNNSNANLKLDASNLSVNGVSTIGSGDGSITKFDIKNGSVVTSSSDMTLAKGKGTQANINISSSELNTGSLSVGEGDNADVKMTGSGASVSSKKTFTVAKGNNASATLNYTGSKIDIGSGYIGEGESAKTQLELNNSALTASGKVFIGQGNTTQTNLTLNDKSSVNVSGEMSVAQGSSASVDVTATNAVLSADSLSLGGGEAAKVTMTGSGATVSSKNTFTVAKGNNASATLDYTDSKIDIGSGYIGEGEAAKTQLELNNSALTASGKVFIGQGNTTQTNLTLNDKSSVNVSDEMSVAQGSSASVDVTITNAVLSADSLSLGGGEAAKVTMTGNRATISSGNTFTVAKGNNASATLDYSDSKINIGNGYIGGGEKAQTVLTLKDSALAATGDVIMGQGQETQTDLTLSPQSSIKVSGNMSIAQGNAASAKVIVDNADLSANSMSIGEGDTAAVTMTGNGATISSGNTFTVARGNNASATLDYSDSKINIGNGYIGGGEKAQTVLTLKDSALAATGDVIMGQGQETQTDLTLSPQSSIKVSGNMSIAQGNAASAKVIVDNADLSANSMSIGEGDTAAVTMTGNGATISSGNTFTVARGNNASATLDYSDSKINIGNGYIGVGEKSHTLLKLDNSTFHAAGNIDIGKGSSTIANVSVGAGSNMSIKGNASIGVGDQAKAKFSVKDSVLNIGSSLVLGQGNSTEAEMSVEHSQLYSGGLLLGTANNAVVSMSANNSEISVVGDYTVAKGDGSEATLIYKNSDINLGNGILGAGSGVKTDLSLDNSKFVASDGIIIGKGDNAITNLSISDHSVFKGERINIGNGSYSKNSISITGNSIFDFGSSQESTIGEGDYSQSLVTINDASVYGDGSLTLAKGNNSFAVLNLQDNAVTNANNISLATGLGSKAIVNVSNMNSGQFNPVSMGAGDGYAEVNFDGVNGYTLSTNFICMDSGSCADTVINVNRGTVSLSGTNDWKGQINVYDGTRLDARGNDAVDGILNVSKEAQVDFNGYSQHMTGIDNKGMIYLSDGSASSDVYLDKDYVAHDGSGVQFGIFGQKEADVMHVKGDTSGSSGIVVTTNSKNKIKKGGDILLVEVNGDSSGSFYLNSLIKNGKEYKVTGDYIDVGAWEYALNKKRKNWYLSVDMRPEPGAFINNSKSMLDMFALQRYDIPGQHRYPTLFENLYNNGMWIQFNNNSGSNSEVYDNLKTSYSLNTMMIGGDIYNWTDGYNYSHIGIMGGMGSAANKTTSTNNKRATGNVDGYTLGLYHVFQQNISDGLNESERQGLWTYSSIQYMDYDNSVSSTNNFKANYGVNGFRLTGEVGYLKNIGGIQPSDFYVEPKLYLSHTELSGGVVEDLQGGKITYPNSLTIIEPGVFFSYRKTHESTSNDEAMFKDYIKQSVVDAWFGGGYSFKTGNYSRTNFDSDMVEYNTSDNFALKSGVEFEFLKDARLLLTSSYSINNDRNLSFILGGNYYF
What are the official names of this protein?
Uncharacterized protein YuaO.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: COBQ_CHLAD
Sequence: MPAPVVMVIGTASSVGKSTLVAALCRLAARRGLRVAPFKAQNMSNNAAVTADGGEIARSTAVQAAAAGIAPTVAMNPILIKPEGQRRSQIIVEGRPWQTLAAGDFWRRKTLLWEVVTRNLDALRATYDLVIAEGAGSPVELNLKAGDIVNMRVAVYAQARTLLVGDIDRGGIFAQLLGTLMLLDPTERQLIQGLIVNRFRGDPALFVDGVRILEERSGIPVLGVVPWIEDLGLAEEDAVAIEQSTPVMAQGITIAVIRLPTIANFDDFDPLAREPGVTVRYIDRPGELAGVAAVIIPGVKHTIAARRWLRERGFDEALRRFPGAIVGICGGYQLLGERISDPLAVEGNGGDEVGLGLLPVETIFVTTKQTTQTVAHARVPWGGQAPLHGYEIHMGRTHRIGAASALLTIIQRGAQAVLEEDGCISPDGRVWGCYLHGLFTNDEFRHGWLRQLGWQPTTSVSGSVDPINRLADHVARALGETVLDRLFRLTE
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PRLD1_MOUSE
Sequence: MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTNRMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMKGFEYILAKLQGEAPSKTLVETAKEAKEKAKETALAATEKAKDLANKAATKQQQRQLV
What is the function of this protein?
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes.  In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane.  Regulates the mitochondrial apoptotic pathway in primary Th cells.  Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number.  May be important for the development of vital and immunocompetent organs (By similarity).
What are the official names of this protein?
PRELI domain-containing protein 1, mitochondrial, Px19-like protein.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: SECA2_STAAW
Sequence: MKHKLDVTINELRLKSIRKIVKRINTWGDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNLYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PGL2_ARATH
Sequence: MNNIEATLFLCFFCIFSSSNVHFAGAKQTAGNITPSENPFTPKASLIRYWNNHINGDSPKPSFFLSKASPLTAVDSTRFASLASNHALNTHHSDFCSAAKLFCFPELAAHSLEKHGDDVNFAAYSGKNFTNYGSDRLSGADSFKNYSGGDNIAVDSFRRYSRNSAGHDDGFTNYAGEVNVADQSFTTYATGTTGGSGEFTNYNTDANEPNGRFTSYSDKANGRSQTFTTYSENGNTGYQSFTSYSKNGNGAPNEFSGYGTGSNVVNTGFTKYGESANGANDSFTSYGENGNVPVNEFKGYGDGGNGAVYGFKNYRDQSNIGVDSFSSYAKNSNNEKVNFVNYGKSFNLGSDNFTGYGQDNVGGNVSFKTYGQGQSFKVYTKDGVVFARYSNNVSSNGKTVNKWVEEGKFFREAMLKEGTLMQMPDIKDKMPKRTFLPRNIVKNLPFSSSTIGEIWRVFGAGENSSMAGIISSAVSECERPASHGETKRCVGSAEDMIDFATSVLGRGVVVRTTENVVGSKKKVVIGKVNGINGGDVTRAVSCHQSLYPYLLYYCHSVPRVRVYETDLLDPKSLEKINHGVAICHIDTSAWSPSHGAFLALGSGPGQIEVCHWIFENDMTWNIID
What is the function of this protein?
Involved in cell size determination.
What are the official names of this protein?
Polygalacturonase 1 beta-like protein 2, AtPGL2, Aromatic-rich glycoprotein At1g60390, PG1beta-like protein 2, Polygalacturonase 1, Probable polygalacturonase non-catalytic subunit At1g60390.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall.
Protein: LEXA_AROAE
Sequence: MISRADPLTARQAEILDFIRHTVESEGRPPTRAEICTAFGFRSPNAAETHLRTLAAKGAIVLEEGRARGIRLVEALGLPLVGHVAAGRPMLAVEHIEARYQIDSALFSPRADYLLRVRGMSMRDAGIIDSDLLAVHRTPQVRAGQVVVARLEDEVTVKTFTREGPIVRLLPANPDFEPIVVDTRHQALDIEGIAVGLVRNGSR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y805_METJA
Sequence: MMYSRKFQILKENIGLYHGDFMDFEVYDTEYMSIIFVKDRLDYTGKEIEPLWAFKTFDIQKDSIVVFRGRMEVTTENMKDLKDIKREKDIKTPIKSEDAINFVVEHFDVIDLKTIYLRQRLLVFIAKEVIESYNIKLKRDGDDLYFEDKKLSVCIACKGTVSAKIHLGINVKSKGAEHVKIIGLEDLGIKDIDKVMREIAINYAKEIDKIERDLRKTLPLI
What are the official names of this protein?
Uncharacterized protein MJ0805.
Protein: DCP5L_ARATH
Sequence: MASESSQSSSPSSSQPPSSVPSPSPGNNVGDTFIGSFISLISKYEIRYEGILYHLNVQDSTLGLKNVRSCGTEGRKKDGPQIPPCDKVYDYILFRGSDIKDLQVNPSPSAQSRQEIQSEQDVNQSPHSRPAMTMSSPISGYDSGYGLGRGSQWINTPALSSKPVPVTQHSSVPLSFQPPSANAGSLTESPVSLIDSTQSNAGSSMPIPSFVQGNKFASSGVPLGMMQKPVSSSSTIPNGPQIIDYFSSPIMGLVDDSSQVVTRSPDVSSNQSYSSNPSPLGQTQLHTPPGLASVSSNLSPPSEAQLSAPNIQKIYPSAPQAIGKVVYDPQSNHPHRSIPHELPAVASNSAPVIPGPLSKSPESFFDMDPSLQSRQQMVYRGQEMFAATNPASANVPSQSFAPRNHAPLLPLPVSAHQSRIPSSSIEYTEEFDFEAMNEKFKKSELWGYLGRNNQRNQNDYGEETAIEPNAEGKPAYNKDDFFDTISCNQLDRVARSGQQHNQFPEHMRQVPEAFGNNFQRPPPLQPGQGAYLAAQTNYRGGYHNNNNNNYYSNSGYGYYSGGRGRGRNTHF
What is the function of this protein?
As a component of the decapping complex, involved in the degradation of mRNAs.  Promotes P-body formation.  Translational repressor (By similarity).
What are the official names of this protein?
Decapping 5-like protein.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: NEB2_RAT
Sequence: MMKTEPRGPGGPLRSASPHRSAYEAGIQALKPPDAPGPDEAPKAAHHKKYGSNVHRIKSMFLQMGTTTGPPGEAGGASGMAEAPRASDRGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSVPAASGGDKEAVARRLLRQERASLQDRKLDVVVRFNGSTEALDKLDADAVSPTVSQLSAVFEKADSRTGLHRAPGPPRAAGAPQVNSKLVTKRSRVFQPPPPPPAPSGDAATEKDRGPGGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTTATTASPAPEEPKAEAVPEEEASSSVATLERGVDNGRAPDMAPEEVDESKKEDFSEADLVDVSAYSGLGEDSGGSALEEDDEEDEEDGEPPYEPESGCVEIPGLSEEEDPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQERWQREMMEQRYAQYGEDDEETGEYATDEDEELSPTFPGGEMAIEVFELAENEDALSPVEMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST
What is the function of this protein?
Seems to act as a scaffold protein in multiple signaling pathways.  Modulates excitatory synaptic transmission and dendritic spine morphology.  Binds to actin filaments (F-actin) and shows cross-linking activity.  Binds along the sides of the F-actin.  May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction.  Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors.  Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors.  May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton.  Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling.  May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins.  Probably regulates p70 S6 kinase activity by forming a complex with TIAM1.  Required for hepatocyte growth factor (HGF)-induced cell migration (By similarity).
What are the official names of this protein?
Neurabin-2, Neurabin-II, Neural tissue-specific F-actin-binding protein II, PP1bp134, Protein phosphatase 1 regulatory subunit 9B, Spinophilin, p130.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Postsynaptic density. Cell junction, adherens junction. Cell projection, dendritic spine. Cytoplasm. Cell membrane. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, ruffle membrane. Note=Enriched at synapse and cadherin-based cell-cell adhesion sites. In neurons, both cytosolic and membrane-associated, and highly enriched in the postsynaptic density apposed to exitatory synapses (PubMed:15514983). Colocalizes with PPP1R2 at actin-rich adherens junctions in epithelial cells and in dendritic spines. Accumulates in the lamellipodium, filopodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment (By similarity).
Protein: POTA_VIBCH
Sequence: MGEIQTLNEQHSVGKPVIRLSGISKSFDGKEIIGNLNLDVNHGEFLTILGPSGCGKTTVLRMIAGFETADQGQILLDDQDVTQVPAEQRHVNTVFQSYALFPHMTVFENVAFGLRMQKVPQSEIEPRVMEALRMVRLAEMAQRKPHQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQSELKQLQRQLGITFIFVTHDQEEALSMSDRIIVMRSGKIEQDGSPREIYEDPKNLFVARFIGEINVFQATTIDRIDEKRIRVDIEGIESIVYYEDEVKAGDKLQVLLRPEDLRIEEIKESEEKGIVGHVTDRTYKGMTLESVVELESGMCVMVSEFFNEDDPDVDHSIGQKVAVTWVESWEVVLNDEQKA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.