PharMolix/UniProtQA huggingface dataset:
Protein: SODF_ECOL6
Sequence: MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: ATPD_STRAW
Sequence: MTAHGASREATAAARERLDALTDSTSVDVVQLADELAAVTALLDREVSLRRVLTDPAQAAEAKAELAGRLFGSQIGGPATDLVTGMVRSRWSQSRDLVDAVEELADIADLTAAQRAGVLDDVEDELFRFGRIVSSNPALRAALTDRTADKAARSELVHSLLGGRATATTERLVTRLVTTPRGRSLEAGLESLSKLAAERRDRLVAVVTTAVPLSDTQKQRLGAALATLYGRQMHLNIDVDPEVLGGMRVQVGDEVINGSIADRLEDARRRMAS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOZ_RHIEC
Sequence: MARVTVEDCIDKVENRFELVLLASHRARLISQGASITIDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEPDPASMIAAGGAAAADSEEQDDLPETITFDQMSEEELLAGIEGLVPPEKSDDY
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL25_SALPA
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: DCE1_HUMAN
Sequence: MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Enzymatically inactive as glutamate decarboxylase.
What are the official names of this protein?
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: AHR_MUSMM
Sequence: MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSTSLPFMFATGEAVLYEISSPFSPIMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSPAPLDSHFLMGSVSKCGSWQDSFAAAGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNNDLYNIMRNLGIDFEDIRSMQNEEFFRTDSTAAGEVDFKDIDITDEILTYVQDSLNNSTLMNSACQQQPVTQHLSCMLQERLQLEQQQQLQQPPPQALEPQQQLCQMVCPQQDLGPKHTQINGTFASWNPTPPVSFNCPQQELKHYQLFSSLQGTAQEFPYKPEVDSVPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLDFVSCLQVPENQSHGINSQSAMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYSSEIPGSQAFLSKVQSRGVFNETYSSDLSSIDHAVQTTGHLHHLAEARPLPDISHLVGSCSSHARMKFIQEQDTGTVRVGHQYTFSKTDFDSCI
What is the function of this protein?
Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer.  Upon ligand binding, translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE).  Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation.  Xenobiotics can act as ligands: upon xenobiotic-binding, activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene).  Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons.  Next to xenobiotics, natural ligands derived from plants, microbiota, and endogenous metabolism are potent AHR agonists.  Tryptophan (Trp) derivatives constitute an important class of endogenous AHR ligands.  Acts as a negative regulator of anti-tumor immunity: indoles and kynurenic acid generated by Trp catabolism act as ligand and activate AHR, thereby promoting AHR-driven cancer cell motility and suppressing adaptive immunity.  Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1.  Inhibits PER1 by repressing the CLOCK-BMAL1 heterodimer mediated transcriptional activation of PER1.  The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.
What are the official names of this protein?
Aryl hydrocarbon receptor, Ah receptor, AhR.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Protein: ALG8_ASHGO
Sequence: MAKRSEKTEGANKSGRRRGPGSDAEGAEDSGTRRYSLWNFWVASTALKLLLMPGYYSTDFEVHRNWLAVTHRLPLREWYVDATSQWTLDYPPLFAWFEWALSQVVPGAVRRDGCLELVAEGRYGWPTVVFQRLTVIASEVLLYVVLQVYVNRSAAQERTVNFVVATSVALSPAFLLVDHIHFQYNGFLFAVLVASIVAARERRYVLCGALFTVALCLKHIFLYLAPAYFVFLLRAYVLDLGEFRFRSYRDLVFAVRWGNLCRLGGVVLAIMAVTFAPFAGVMPQLMARLFPFSRGLTHAYWAPNFWAIYSFVDKVLTFLMLRVPYVYKLATSLVQPPLIPASIDEIRARMAAGNHGTRGLVQDVSFVILPQIQPKLTFLLTLFYQVLAVLPVLFDPSFKRFIGSLSLCGFSAFLFGWHVHEKAIMLVIVPFSFLVSFDQRLLTPFRLLTASGYVSLFPLLYSSSSFVIKVLYTLIWCIVYHSALKRTVPASASVQRRVFFFDRLAAVYVMLLLPMVLGVKYLELLEGKFEALEKYQFLGLMCYSIYCAIGVCTSWMGLSWLYNFDEPLWV
What is the function of this protein?
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NIT_ASPOR
Sequence: MTTPQPSQVRVAVTQAEPVWLDLKATVDKTCSLIAEAASKGAQLVSFPECWIPGYPAWIWTRPVDQELHSRYIQNSLTVSSPEMTQICKSANENNVIVVLGFSENIHNSLYISQAIISNTGSILTTRKKIKATHMERTIFGDAFADCLDSVVETAVGRVGALSCWEHIQPLLKYHTCAQREAIHVAAWPPLFEWGGPEDESLFSMSRDGTIALARTYAIESSSFVLHTTAVISQEGVEKMRTATGAIMNMPGGGSSAIFGPDGRLLSKPLLPTEEGIIYADLEMHDIYKTKAFVDVLGHYSRPDLLWLGVGSCDRRHVKEDAEERREDRVEVL
What is the function of this protein?
Nitrilase that hydrolyzes preferentially phenylacetonitrile, (R,S)-mandelonitrile, and 3-indolylacetonitrile.
What are the official names of this protein?
Arylacetonitrilase, NitAo.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: DNLJ_BACTN
Sequence: MDIKEKIEELRAELHRHNYNYYVLNAPEISDKEFDDKMRELQDLELAHPEYKDENSPTMRVGSDINKNFTQVAHKYPMLSLANTYSEGEVTDFYERVRKALNEDFEICCEMKYDGTSISLTYEDGKLVRAVTRGDGEKGDDVTDNVKTIRSIPLVLHGDNYPSSFEIRGEILMPWEVFEELNREKEAREEPLFANPRNAASGTLKLQNSSIVASRKLDAYLYYLLGDNLPCDGHYENLQEAAKWGFKISDLTRKCQTLEEVFEFINYWDVERKNLPVATDGIVLKVNSLRQQKNLGFTAKSPRWAIAYKFQAERALTRLNMVTYQVGRTGAVTPVANLDAVQLSGTVVKRASLHNADIIEGLDLHIGDMVYVEKGGEIIPKITGVDKDARSFMLGEKVRFITNCPECGSKLIRYEGEAAHYCPNETACPPQIKGKIEHFISRKAMNIDGLGPETVDMFYRLGLIHNTADLYELKADDIKGLDRMGEKSAENIITGIEQSKTVPFERVIFALGIRFVGETVAKKIAKSFGDIDELRQADLEKLISIDEIGEKIARSILLYFSNESNRELVGRLKEAGLQLYRTEEDMSGYTDKLAGQSIVISGVFTHHSRDEYKDLIEKNGGKNVGSISAKTSFILAGDNMGPAKLEKAKKLGVTILSEDEFLKLIS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL29_PSYA2
Sequence: MKISELRDKSLEELTQLLDEKQLDAFRIRMAKATGQLGNTHEVRVNRRAIAQLQTLINEKQRGDS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: XPT_HELMI
Sequence: MQELKDRILAEGEVIGTHILKVDTFLNHQIDPAFILRMGKELADRFAGAGITRVLTVEASGIAVASAVALSLNVPVVFAKKKQASTQSDVYTSQIYSFTRQESVNITVSKKFLPADDVVLIVDDFLAHGEALKGLVDIVRQSGAGLAGAGIVIEKLFQRGGAALRAEGMRIETLAAIERMEPGKIVFA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_ECOHS
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STAHJ
Sequence: MSLKEEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCRMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIDTYPMNWPIGMGQNFFGIIDRDSKSIEPFRDEENVLHLNDDYELQEEHAIRNDSAFAQAIEEFMLVKEAGEEFDNDALLNGELTPVFFGSALANFGVQNFLNAYVDHAPMPNARQTNEEVEVSPFDDEFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTSKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQKYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDDIQDKMNTSRSILVKDRYDNFVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHSG_THELN
Sequence: METVVNQIKSKLPENLEGLLDLAYNYWWSWNRRATKLWEKIDPEHWWEYKNPVKLLLDTPEERLKELSKDDDFINLYELVIDQFRHYMNPESTWFSTNYPKWEEPVIYLCMEYGISKSLPIYSGGLGILAGDHIKTASDLGIPLIAIGLLYKHGYFKQEIDKDGKQIEVFPEYNPEEMPIKPLTTEKGKPLLIEVPIEDRIVYARAFEVNVGRVKLYLLDTDVPQNSPDDRTICDYLYNAEIDKRIKQEILLGIGGMRLLRMLGIDPAVIHLNEGHPAFANFQRIAWYMEEGLNFLEALTVVRGTTIFTTHTPVPAGHDKFPIAEVEKRLAKFLEGLPKDEFLNLGREGDQFNMTLLSIRTSSYVNAVSKLHSKVTKEMWRHLWNGVPLDEIPVEGITNGVHTKTWLHNEIKKLVDRYIGRVWRDYAELEGLWYGVERIPDEELWEAHLKAKREFIELIKRKIKERNERLGIEEPLPEIDENALIIGFARRFATYKRATLILTDLERLKKIVNNPERPVYIIFGGKAHPRDEAGKEFLRKVYEVSQMPEFKNKIMVFENYDMGSARAMVAGVDVWLNNPRRPLEASGTSGMKAGLNGVLNLSVYDGWWVEGYNGKNGWVIGDESLEPETEKDNIRDAQSLYNLLENEVIPTYYENRARWIYMMKESIKSIAPRFSTHRMVKEYVDKFYSKALANAILLQRDSFKATREIASWKAKIFNSWDKVEIERIITHDATGVEVIVNLDGLSPEDVKVEIYYGVKAEGYAIEKPYVIELKHPQSLGGNRWLYRYEGNALKNLGHPCWHYAVRVYPYHDKLPHKFLLGLIKWKGFFEL
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Catalyzes the phospholytic cleavage of maltodextrins with a minimal chain length of five glucose residues to yield glucose-1-phosphate.  Low activity with tetraose and no activity with triose and maltose.  Long maltodextrins (8 to 15 glucose units), amylose and starch are not as good substrates as maltoheptaose.
What are the official names of this protein?
Maltodextrin phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: TI17B_MOUSE
Sequence: MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRFRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSISSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLTPKEGSPAPGYPNYQQYH
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim17-B.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CCG2_HUMAN
Sequence: MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKENKDSLHSNTANRRTTPV
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization.  Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.  Thought to stabilize the calcium channel in an inactivated (closed) state.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Transmembrane AMPAR regulatory protein gamma-2, TARP gamma-2.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: METXS_ACIB5
Sequence: MSFPADSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADKSNAILICHALSGHHHAAGYHHEDDKKAGWWDSCIGPGKAIDTNKFFVVALNNIGGCSGSTGPTSPNPENDNRPYGPDFPLVTVRDWVKTQAMLSDRLGISVWYAVVGGSLGGMQALQWSVDYPDRLQKCVVIASAPKLSAQNIAFNEVARQSILSDPDFHHGRYLEKDSYPKRGLILARMVGHITYLSEEAMKQKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYGHSLTEAMSKTKCQFLIVSFTTDWRFAPSRSQEIVDALITNQKPVSYLDIDAEQGHDSFLFPIPLYVKTLRAFLGGEEHLKSTSLEAS
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_CROS8
Sequence: MKVTLPDFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVETIEERPGGAANVAMNIASLGASSRLVGLTGIDDAARALSQSLAQVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFDGVDPEPLHERINQALGQIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKTEQDIVERGMKIIADFDLSALLVTRSEQGMTLLQPGKAPFHLPTQAQEVYDVTGAGDTVIGVLAATLASGNSLEEACFFANAAAGVVVGKLGTSTVSPVELENAVRGRAETGFGVMSEAALKEAVLAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTRRLKGDTRPVNPQEQRMIVLAALEAVDWVVPFEEDTPQRLISEILPDLLVKGGDYKPEDIAGSKEVWANGGDVMVLNFEDGCSTTNIIKKIQKNS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: PANC_SALTO
Sequence: MTELVHTRADLAAARDGLTGTVGVVMTMGALHSGHETLLRAAREQADNVVVTIFVNPLQFGPDEDFDRYPRPLDEDLEICRRAGAAVVFAPAVPELYPQGQPRVWVNPGQLGEELEGQSRPGFFHGVLTVVLKLLQLTRPDRAFFGEKDYQQLTLVRRMVRDLEVPVEIVGVPTVREPDGLALSSRNRYLSPDGRTAALSLSGALQAGVAAAAGGADAGAVLAAAHAALDAGPPGVQLDYLVLTDPELEPGPVTGPARLLAAAWVGTTRLIDNVSVQLAPRY
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC42_HUMAN
Sequence: MSYYLSSENHLDPGPIYMRENGQLHMVNLALDGVRSSLQKPRPFRLFPKGFSVELCMNREDDTARKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVISEKLEEIKSFRELTCLDLSCCKLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGVRKMTAPVRVMKRGLENLTLLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKTVKHKLQTHIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVTAEAVKPRETSEPRAAAQRFYGKRSRAEAPLKCPLADTHMNSSEKLQFYKEKAPDCHGPVLKHEAISSQESKKSKKRPFEESETEQNNSSQPSKQKYVCLAVEDWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.
Protein: YRA2_ZYGRC
Sequence: MSVDNVLDKLVDEKKYRRRDLRNSLASRIGIEDRPSSTPREPPKKRLRFTNVPLDVSDFTLEDMVKEFAEPIYCNFYDLKDSRTAVFEFEDPSVMERVVEKYNETPLNGGTVTVEIFEQERRPDRRRRTQRDNRRGNGRGSRGSHYKRQDRPAMEDELNAELEDYMKSS
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YGFZ_YERPS
Sequence: MAYHTPFAAQPPVASSGLPLTLISLDDWALVTLTGADRVKYLQGQVTADIDALSADQHVLCAHCDAKGKMWSNLRLFYRGEGLAFIERRSLLDNQLSELKKYAVFSKVVIAPQPDAVLIGVAGSQAKTALAEIFTELPSAEHPVTQMGNSTLLHFSLPAERFLLVTDTEQAQQLVEKLAGRAQFNDSKQWLALDIEAGFPIIDAANSAQFIPQATNIQALNGISFTKGCYTGQEMVARAKYRGANKRALYWLAGNASRVPAAGEDLEWQLGENWRRTGTVLSAIQLNDGTVWVQAVLNNDLAADSVLRVRDDALGTLAIQPLPYSLAEDK
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYOX_CHICK
Sequence: MRCAPPGLLLAQLHACIFWSGLWPAGCQSPPAAWRQRIQWENNGQVYSLLSQGAQYQPPRRRQGAEPASSPVLLLRGNGSVPRAAAAAAARPQPEPQPQAQPQPRPRSSRRQPLGRRHWFQAGYRAPSGSARPAPRRRPRGRRSRRRERAERRRAAAPSGLRPGREDVMVGDDPYSPYKYTDDNPYYNYYDTYERPRQGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCLASSAYRADVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISPY
What is the function of this protein?
In addition to cross linking of extracellular matrix proteins, it may have a direct role in tumor suppression.
What are the official names of this protein?
Protein-lysine 6-oxidase, Lysyl oxidase.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: INS_CHIMO
Sequence: VPTQRLCGSHLVDALYFVCGERGFFYSPKPIRELEPLLGIVEQCCHNTCSLANLEGYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YKKA_CAEEL
Sequence: MSTYIQVNIYNQTLEVLKMRGLDLQSILKTIGCPDSWVTEVPIHPPAQKIQKPATPPTSCAPQLVSSPKCLESISAQSQNVLKKPFKSISAELGFAQPLNLVDTLGLKPRDSDAMSRGKRPASVLKGLFDDWDPTANLDIPGTSSDIPSDPSSALKVPKKEVLDESEEILDQTSGSSSFSLNDSEQANEQERNIIEDLLRQQMFTESKIKNEEASLLKGLKKGLGEELESSHANYVITCNFPGCGLKYNWRVKYGKLRLLDHALTHSNRKIPCKLCGFECTNVRRMRSHYAKAHPNERVEGYGMKALVSGDSSRIGDGVDGDIDQQVSDDELKELWNNCFSESIHLVGQASGFVEGEKYRRMTKRRKLDREAMNSMNFMF
What are the official names of this protein?
Putative zinc finger protein C02F5.12.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNB_ECO7I
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.