PharMolix/UniProtQA huggingface dataset:
Protein: GLGA_YERPP
Sequence: MRVLHVCSELFPLLKTGGLADVIGALPAAQLAEGADVRIILPAFPDLRRGIPETVLVREIDTFAGRVALRYGHYRGIGIYLIDAPALYDRAGSPYHDASLYAYSDNYLRFALLGWMACELACGLDGYWRPEVVHAHDWHAGLTCAYLAARGRPARSVFTVHNLAYQGLFSADHLSELHLPAEFFQIYGLEFYGQISYLKAGLFFADHVTTVSPTYAKEITQPAFGYGMEGLLQALARQGRLTGILNGVDSDIWDPQSDTLLPTRYDAENLQAKAINKTHLQTAMGLQLAENKPIFAVVSRLTVQKGLDLVLEALPELLALGGQLVVLGSGDATLQEAFLAAAAEHSGQVGVQIGYHEAFSHRIIAGSDVILVPSRFEPCGLTQLYGLKYGTLPLVRHTGGLADTVVDCALENLADGSASGFVFNECEAQALVKAIRRAFVLWSRPKHWRHVQRHAMRLDFGWQLAAVDYLSLYRRL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: LDH_PSELT
Sequence: MKVSIFGAGRVGISIAYSLLHTKIADEMVIVDIDIKRAEGEVLDLYHSTPFLKRCNITAGNPHDILNSDFVIITAGASQSAGESRLSLTKRNVKIIRQIAAQIKKYSPDAIVINVSNPVDVLSYVLWKETKFNWRKVIGTGTILDTARFRALVAKQCGVSPMSVHAYIIGEHGDSELLVWSNATIGGVSIKRFCQFCTNKNCTPLESLFEQTKNAAYEIIEKKGATNLAIGTATAALVESIYRDEKRVWTVSVFQDNLYIGFPAILGKNGVEKLVPVKLNSVEKEAFERSKEVIKKYIKEGEKSEREESSSN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATD_SCHPO
Sequence: MASKQRENVFPTRMTLTTMKTRLKGAQTGHSLLKRKSEALKKRFREIVVNIEQAKQKMGRVMQIAAFSMAEVGFAMGNNINFEIQQSVKQPRLRVRSKQENISGVFLPTFEMNLDESIDDFQLTGLGKGGQQIQKARQVYEKAVETLVQLASYQSAFVLLGDVLQMTNRRVNSIEHIIIPRLENTIKYIESELEELEREDFTRLKKVQKTKENAEKADSVTKEEHQGGSNTLQQTKDVGGAIAPAAEVGKEVINEVENSKDDTYSLPSTSTDDEEENDSDEEVIF
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit D, V-ATPase subunit D, Vacuolar proton pump subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y473_LIGS1
Sequence: MINVYDTANQLEKDLRESQEYKDLQAVVAKVKADDATFAVYKKLREAQKTLQEQQMQGTLDEKVMKSLQEISQEASQYPLMMELMEKERAISVLIDDLNKIIFKPLSEVYDIEG
What are the official names of this protein?
UPF0342 protein LSL_0473.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: SNX4_CRYNJ
Sequence: MDQDGFHSIAWDDAPSSNPPLSAPSPSQSPFEEGFESISPSSAQPPASDQYEGYDNSKAGEAGDVGVTLDRRERLGGHEVDGSVWNGKWMDVQVREPAKEHEGSKDMYVSYAVKTETSLPTFRKPLTVVRRRFQDFVFLREHLVKNFPACVVPPIPDKHRLEYIKGDRFSPEFVERRRLDLQRFADRIARHPVLQRSQLVNDFLQSTEWSVAKHHHISHPPPESHASLIDSLSDTFINAFSRVRKPDARFVEMTEELERFEEGLTGVERVVGRGKSRVDDLAADYQDMAAAYQGLGYLESGITEPLNRFAEKMLDFSTLLKHMNNTTIEPFLSSSHSLLSYSATHRNVIKLRDQKQLDFEELSAYLSAIVSERDRLAALSSGHTAAPVGLGTYLRDQMDKLRGTDDIHTRRERMRKMDGKIKELQDAVTLAHETSNAFSEEVIKEHAYFELEKKQEMKDALQAYTDGQVEMLQQAMDDWDRIIPLLQRIRVDV
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells.  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures. Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures.
Protein: PHIPL_HUMAN
Sequence: MEVPRLDHALNSPTSPCEEVIKNLSLEAIQLCDRDGNKSQDSGIAEMEELPVPHNIKISNITCDSFKISWEMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAKAVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTADYSKVHLTQLLEKAEVIAGRMLKFSVFYRNQHKEYFDYVREHHGNAMQPSVKDNSGSHGSPISGKLEGIFFSCSTEFNTGKPPQDSPYGRYRFEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPVGSPGDEFCKQRLPQLNSKDNKFLTCTEEDGVLVYHHAQDVILEVIYTDPVDLSVGTVAEITGHQLMSLSTANAKKDPSCKTCNISVGR
What is the function of this protein?
May play a role in the development of the central system.
What are the official names of this protein?
Phytanoyl-CoA hydroxylase-interacting protein-like.
What is the protein family that this protein belongs to?
Belongs to the PHYHIP family.
Protein: DEOB_SHESR
Sequence: MKRTVIMMLDSFGVGAAGDAAKFGDLGSDTFGHIAKACAEGKADIGREGPLTLPNLARLGLAHAAMESTGAFAPGFADDVELIGAYGHAQELSSGKDTPSGHWEMAGVPVLFDWGYFSEHQNSFPKELTDKILARAGLDGFLGNCHASGTTILEELGEEHMRSGKPIFYTSADSVFQIACHEGTFGLENLYRLCEIAREELEPYNIGRVIARPFDGTGPNDFARTGNRKDYSLEPPAKTVLDKLKAAGGEVVSVGKIADIYAYCGITKKVKANGLEALFDATLAEVKSAGENTIVFTNFVDFDSHYGHRRDVAGYAKGLEYFDSRLPEMLSLLDEDDLLILTADHGCDPTWQGTDHTREYVPVLAYGAGLKAGSLGRRNSFADIGQSIASYFKLEPMEYGESFI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_HELAH
Sequence: MAYFLEQSDSEIFELIFEEFKRQNEHLEMIASENYTFASVMEAMGSILTNKYAEGYPNKRYYGGCEVVDKVESLAIERAKKLFNCQFANVQAHSGSQANNAVYHALLKPYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVGLDGYIDYGETLKIAQSVKPQIIVCGFSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVASEHAHPFPHCHVVSSTTHKTLRGPRGGLILTNDEEIAAKIDKAIFPGTQGGPLMHAIAAKAVGFKENLKPEFKTYAKLVKSNMQVLAKVLKEKNHKLVSDGTSNHLLLMDFLNKPYSGKDADIALGNAGITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGTKEFEIIGNKISDILNDINNVSLQLHVKEELKAMASQFPVYHQPIF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_RHOBA
Sequence: MASIEERVVDIVSEQLGVDKDKITRETSFVNDLGADSLDTVELVMELEEEFDISIPDDSAEKIQKVGEAIDFIEKEKGEDA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_PARMW
Sequence: MAKGGAKKAAAAAARAAANRMLADNRQARHQYEILETLETGIELVGTEVKSIRNGKANLRDGFCLIRNGELQLHNVHISPHSHAGAYFNHDPLRTRKLLAHRREIDKLRGQLDQKGLALIPLNIHLKGSWIKLTIGLGKGRKLHDKRAAEKEKQSKKEVKAAIARF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: EFTS_PARD8
Sequence: MAVTMADITKLRKMSGAGMMDCKKALTESDGDIEKAMEIIRKKGQAIAAKRSDREAAEGCVLAKKDGEFAAIIALKCETDFVAKNEDFVALTQAILDAAVANKCRTLDEVKALPMGKGTIQEAVTDRSGITGEKMELDGYCVVEGAYTTVYNHMGKNQLCTIAAFNKESEEAAHNIVMQIAAMNPIAIDEAGVPESVKEKEIQVAIEKTKAEQVQKAVEAALKKAGINPSHVDSEAHMESNMDKGWITAEDVAKAKEIIATVSAEKAANLPQQMIENIAKGRLGKFLKEVCLLNQEDIMDGKKTVRETMKEIDPELQILAFKRFTLRAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_ECOK1
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: RRF_EHRRG
Sequence: MINTIKQDAKNRMEKTLSVYLSDVDGIRTGRARASVLDGIVVETYGGRVKLNTISSISVSDNKTLLVKVWDINNVGAIKTAIINSNLGFGFSCEGAVIRLTVPDMTQDMRKNLVKLLGKISEDCRISIRNIRRDIMDKLKIMQDNKDISEDDLRIAGVEIQKITDEIIKKINDTFLAKEKELLHV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6874_DICDI
Sequence: MKTLRELRNKISFDKNIDSGSSSSNIGGSSSNSSGTTNKRSSGNFNGSSASSSPSSSTNIDYNIPTFSNIQNIDWKSISSVEKIDFGNSNIFLLITFNNNNNINNINNLNCNCVNNNNNNICNNNCINNNNNTNDENPSIINNYNESQILLKSSSTIAHDVYAYVLEGILKYPIPEMRLLDFSNLEYTEMSYNLLIHSKDDQSLNDFIKSELEKSFFLILEYRNNGKRFNELNHKEYFSGSKGGKKFKQLGKIIAFDIFCNNFCKLPSPPLNWNSSTFFSNILCYDSPDKNGWYFSLINSNISFLNTSPFTIGYRDHLNRLKLLLFSIFQNPSTESVQIKLMRDHLLKCQGIKLSGSSVSYLQKGIAKGIKSIVNCINFTVLENTKEKVKNIVKLDNNNIWKKSIDSIYCPFLLDVLNEIVIEFANYREKTYFIKA
What are the official names of this protein?
Putative actin-fragmin kinase DDB_G0268748.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AFK Ser/Thr protein kinase family.
Protein: RNFH_PSEA8
Sequence: MAEIAVEVVYALPERQALLRLSVPAGTSAREAVLLSGIAEAFPGLDVQGCPLGIFGKLLARPEERVLEAGERVEIYRPLIADPKEVRKQRAARARSEREGG
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: TRPA_FRATM
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEILDTLVSSGADALELGIPFSDPLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISELGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AZOR_DESVH
Sequence: MATILYIKASPRGERSHSVTVADAFVKAYSEANPGDVVRVLDVFEADLPAFGTDAVVARYLSGQGDPLSPAQEAAWAAVKRQVEDFKTADKYVIALPMWNFSIPWRLKQFFDIIIQPGLTFSYDEQGYHGLVTGRPVLVSYARGGAYPAGTPAEGWDFQKRYLEHILGFIGFTDIRSVVVEPTLAGGPDTAQAKRAEAVEQARRMALEF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CYAY_ECOLC
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ISCA_SALA4
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTAEDTVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFSNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CDK4_XENLA
Sequence: MSKEMKGQYEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRLEHFDHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPGLPLETIKDLMKQFLSGLEFLHLNCIVHRDLKPENILVTSGGQVKLADFGLARIYSCQMALTPVVVTLWYRAPEVLLQSTYATPVDVWSAGCIFAEMFKRKPLFCGNSEADQLCKIFDIIGLPSEEEWPVDVTLPRSAFSPRTQQPVDKFVPEIDAMGADLLLAMLTFSPQKRISASDALLHPFFADDPQACSKQEHFTHICTATDEVK
What is the function of this protein?
Probably involved in the control of the cell cycle.
What are the official names of this protein?
Cyclin-dependent kinase 4, Cell division protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_CAMJ8
Sequence: MKHIEIYTDGSCLNNPGFGGWAYILRYKEYQKEGFGAEANTTNNRMELMAIIESLKALKEPCEISLFTDSNLMVQSINEWLEGWIKKDFKGKKNIDLWKEYIKVAKSHKIKAFWVKAHNGHLENERCDTLAREAALKIARENDEKH
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_CLOBB
Sequence: MDFTNYKAHELKNLISKKEASVEEVTKAHLENVKNIDEKVNAFLYIAEEEALNDAKALDEKLSKGEDIGLLGGAPLGIKDNISVKNMQNTCASKILEGYISPYDATVSESVKSQGGVILGKLNMDEFAMGSSTENSAYKITRNPWDLDRVPGGSSGGSAAAVASKEVPLALGTDTGGSVRQPASFCGIVGLKPTYGRVSRSGVVAYGSTLDQVGTLGRDVKDCALLTQVISGVDHRDFTTANINVPNYENSLSENIKGKKIALPKEFFKDGLDPKVQKAIYDALEVFKANGAEITEVSLPLADYAISAYYLLACAEASSNLARFDGVRYGHRSESVEDAVDVYFKSRSEAFGKEVKKRIMLGTYALSAGYYDAYYKKALKVRNLIKGEFENIFKDFDAIISPTAPTPAYKIGEKTENALEMYLGDIYTVPVNIAGIPAISLPCGVADGLPVGLQIMGNYFKEDTLFNLAYSYEQSTKWHEMHPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: VTA1_DICDI
Sequence: MDLASLPPALKPIIPYLKQSQQLEKHDLLMAYYCRVHAIQMAMDIKQKMGASGSFLSIPIVKILDQGDADKAKLGSRLDEEDEAKYVEAFAMKAFSFADTQDRAGKANKATSTTFYSAFLFFNVLEHMGEVSEEVKLKKKYASWRSVDINTAIKNGVAPSPPPSIDQNEEGGASGETEEDAQLKQLEMELNLAKATLQQDNNNNNNMSSSTIITTNSVSEGMSSSLSFPSFPSIPNNNNNNNNTTPSFPSFPSFPSPTNSDNNSNNNKPAFPSFPSFPSPPTTTNSDSAPSFPKFPSTPSPTNSSSNNSQQPSFPSFPSFTSPTNSNNNNNNSQQPSFPTFPNSTNQKRQVFESDEEEEQEEVEDYSEKQQQKSTSSSFPKFPSNSHNNEYNQPPPPAYEFKQSPPQQHKQSPPQQHHNSHDNEALIKYQQQVAQQNLTIQKQKHQNQMLQDEVEQKQQQIQLQQQQLQQQQQQIQLLQKQIQQQQKQLMSGGGGGGNMSMNLNHTPSDTDKASAEKYSKWVISSLQFDDVPSAVKNAKLSLKYLTGEDS
What is the function of this protein?
Involved in the endosomal multivesicular bodies (MVB) pathway.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins.  Thought to be a cofactor of VPS4, which catalyzes the disassembly of membrane-associated ESCRT-III (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein VTA1 homolog.
What is the protein family that this protein belongs to?
Belongs to the VTA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: REEP5_DANRE
Sequence: MAAALKQRFDNALHEKNMVTDLLAKIEAKTGVNRSYIAYAVIAFIAIYLVIGYGASLLCNLIGFVYPAYISIKAIESPAKDDDTKWLTYWVVYGVFSVVEFFADIFLSWFPFYFLAKCAFLVWCMAPTPSNGSIMLYTRIIRPFFLKNEAKIDNVMKDLTDKAAGAADKIKDEAKKATANIMFEEKKHY
What is the function of this protein?
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
What are the official names of this protein?
Receptor expression-enhancing protein 5.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RPOZ_SYNS9
Sequence: MIECSWLVISAGVDSSDLAKRGESLIRQSSNRYLTTVRIAFRAKQRRFDDFDGLLEESSVKPVQRAIVELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: KDSB_WIGBR
Sequence: MEFIVIIPARFFSKRFPKKPLININGKPMIIHTIENAKKSGASRVIVVTDNNEIYSLVNKNGIEVLLTKKEYNSGTERLIEAIEKFKIKDNQIIVNLQVDEPFLNSDNIFNVAKKLKEKNLIVSTLAIPILNKKEIFDKNIVKVVIDINGYALYFSRSVIPWCENYNSYYIKNNFLKHVGIYAYYAKFVRLYSNYNSSKLEKMENLEQLRILWYGKRIYVSVENIKNCFSINTPSDMLNIKSF
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MXIK_SHIFL
Sequence: MIRMDGIYKKYLSIIFDPAFYINRNRLNLPSELLENGVIRSEINNLIINKYDLNCDIEPLSGVTAMFVANWNLLPAVAYFIGSQESRLINHSEMVISYYGGKISKQGEAAIRSGFWHLIAWKENISVGIYERINLLFNPIALEGNYTPVERNLSRLNEGMQYAKRHFTGIQTSCL
What is the function of this protein?
Necessary for the secretion of IPA invasins.
What are the official names of this protein?
Protein MxiK.
Protein: CT5H_CONTE
Sequence: NCCPIDEESCCS
What are the official names of this protein?
Conotoxin tx5h, Conotoxin Tx5.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RK20_CARPA
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQRIRALVSAHRDRGRKKRDFRRLWITRINAVIRGDGVSYSYNRFIHNLYKKQLLLNRKILAQIAISNRSCLYTISNEIRK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPF_ENDTX
Sequence: MEIIQKFGLEAKLFLFQLINFLIIVFILKKFLFAPLKKILDERKRKIEQSLQDAENAKIALENASEKKKNILAKAKSSADTLMATVKVSIKETKEKAVIEAKQRSEQIIDEAKQKAATEFESMNKKIGKISVDISGKVMSKVLSDLFTETEKQKLMSRALEKIDENIKN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RNB_ECO24
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_OEDCA
Sequence: MNLLTIFNILPLGEGFGFNDNILETNIINLAAVVGIVVFFVGKNFSILLENRQQTILNNLREANQRASEALERYNQAKKQLELAEKKAKDIRQEGTLKARQEKENCFNQYKLDLVRLEEYKQETLQFYQQKAFQQIYVSIVSRALGEVKQKFNKPLSEQFHATINNFVIARLTEYNP
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: WNTG_MANSE
Sequence: GMSGSCTVKTCWMRLPSFRSVGDALKDRFDGASRVMVSNTDLEAPTQRNDAAPHRAPRRERYKLKLQPHNPDHKSPGSKDLVYLEPSPGFCEKNPRLGIPGTHGRACNDTSIGVDGCDLMCCGRGYRTETMFVVERCNCTF
What is the function of this protein?
Segment polarity protein.  Binds to the frizzled seven-transmembrane receptors.  This protein is probably a growth factor (By similarity).
What are the official names of this protein?
Protein wingless.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.