PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_MASV1
Sequence: MASANQAAKAEAKKVIEKVAKEVIKETKNSAQRNQGPGKRWNSKKGRHMPKNNNNKGMKRTVDNEVKQKLKKEGLEGPRSRFSVRVSATIGKIGPNKEQGPELQIATFLHPSLMKEPNDGTNFGPLQAAAAQWGLWRLSSLEVKCTPLVGSSAVTGSIYRMSLNLTQSPGNASWGGLGARKHKDIPAGKSVSWKLQRGDLAGPRQTWWMTDTNEEGGQSCGPMLEIHGLGKTSSTYQSQDWTGDLFIVEVLGRWEFTNYNAKPALGTLDRKSEDYASDATGPGIMVGDDGVMKMTLPTASSLARFMSDASERSPVNEGSVGETIWHIVDEGAGLASSVAPTPFSWLIKGAWWFVKKLAGRSGANADEQYVVYASLADAQNNKPVMANRFDHTKKATTLTVTQVNSPNTGPGVTQAAYHTENPFPLVPATQPPPPRSIVVVNATARPFGYVKYNTGDSNVKSHGKFDGTQYHFTLKRGSTVSYASAAYILTDVSMLTYEGNRVTGCYDPGWMEPTGITVHYRNESSAFGRVLAYEIDQWGSTSDNHFTIGVWLVQTIKDLPAHDTTVWPYIPLPYVSAGNCTAPPVQVALDKACVPYLTKVGVTSHQQCTVRQPQVRSGTFMLVYSIGTNTPATTAGFTTGQPLGEATNASALPEGKISTSGFWERALSAVAPYQDFISVKFTLPQGPHADPRVDALLDLIQQRFNLKPVDASESEDEDEDSPSGSEEEPCGEEPTPPQPTPRLKLAKEMMYEALRDSDWTHVDAEALLAAISSKN
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes.  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: YHJO_BACSU
Sequence: MLTSFHSIKSRYTAPVRLRFFGELLTSLTGAMMGPFMVLYLHEQLNGSIMMPMLIISLQPFADIFLTLAAGRVTDRLGRRTAILTALLLQSAAMTGFVFAEHAYVFAILYVMNGIGRSLYIPASRAQIAESTPESRRSEVFAVINAIYSTGLTAGPLVGMLLYNHNPVWIFALDAAALFIYFLIAALKLPETKPLHPAVTPKMSASFTIYRPVLLLLLLSLPISMLYAQTETTYRLFSKNMFSDYLSMLTIYSAAKALFSCVLQVPLVKGTEKLSMKTILFITYICYSLAAAGFACSTSLTMLLVTAAVMTVGESIGLTHIQTFISKLAPPHLLGRFYAVYGLHWDISRSIGPLAGGLILTSFGGEVIFYALAVCLLTAGLSLTYTIEKLEHKVIRKVNRL
What are the official names of this protein?
Uncharacterized MFS-type transporter YhjO.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATN4_MOUSE
Sequence: MRGPCCWPLSLLLLFLQSWETQLQSAGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRTMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELVHGCQHLCVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEHLCVNSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLAGPQCRCREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK
What is the function of this protein?
Major component of the extracellular matrix of cartilage.
What are the official names of this protein?
Matrilin-4, MAT-4.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_PROMS
Sequence: MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISFGTKKMENDPKGLQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVHPTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PUMP5_ARATH
Sequence: MGLKGFAEGGIASIVAGCSTHPLDLIKVRMQLQGESAPIQTNLRPALAFQTSTTVNAPPLRVGVIGVGSRLIREEGMRALFSGVSATVLRQTLYSTTRMGLYDIIKGEWTDPETKTMPLMKKIGAGAIAGAIGAAVGNPADVAMVRMQADGRLPLTDRRNYKSVLDAITQMIRGEGVTSLWRGSSLTINRAMLVTSSQLASYDSVKETILEKGLLKDGLGTHVSASFAAGFVASVASNPVDVIKTRVMNMKVVAGVAPPYKGAVDCALKTVKAEGIMSLYKGFIPTVSRQAPFTVVLFVTLEQVKKLFKDYDF
What is the function of this protein?
PUMPS are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation.  This leads to a decrease in the efficiency of oxidative phosphorylation and an increase in heat production.  May be involved in protecting plant cells against oxidative stress damage.  Recombinant PUMP5, reconstituted into liposomes, transports a wide range of dicarboxylic acids including malate, oxaloacetate and succinate as well as phosphate, sulfate and thiosulfate.  However, it is unknown if these transports are of any biological significance in vivo.
What are the official names of this protein?
Mitochondrial uncoupling protein 5, AtPUMP5, Mitochondrial dicarboxylate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: H4_PLADU
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS11_SALSV
Sequence: MAKAPVRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GABD_SINFN
Sequence: MTLTSALTRHLKCPELFRNLANEPHPSVAGQRQRFSVFNPSTGELLAEVPDMGAADAHAAIERADAAQEPWSGLTARARSDILWKWHRFILEHSDDLAAILTAEMGKPLGEAKSEVQHAAAYLQWYAEEANRIYGETISAPSTDRRMLVIKQPIGVVGAITPWNFPASMVARKISPALAAGCTVVLKPAEQTPLVAGAMFALAKLAGFPDGVLNLVYASEGDAIGRELCTNPKVRKISFTGSTEVGRLLMRQCSDQIKRISFELGGNAPFIVFDDADIDAAVDGAIQAKFRNAGQTCVSANRIYVQSGVYAEFAEKFTERVRTLKVGDGFDPNVAIGPLINQEALKKIELHISDAVQKGARVRSGGRRTGSSGTFFEPTVVTDVSKTMRLAEEETFGPLAPLLRFDDADHVVREANDTIYGLAAYFYASNLKRVWRVAEALEYGMVGINTGRMSSEAAPFGGVKQSGIGREGSRHGLEDYLDMKYLCVGGL
What is the function of this protein?
Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.
What are the official names of this protein?
Probable succinate-semialdehyde dehydrogenase [NADP(+)], SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PYRG_NEIMB
Sequence: MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKERRGDYLGGTVQVIPHITDEIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMRSQLGRNNTLFAHLSYVPYIAAAGEIKTKPTQHTVKEMLSIGLQPDILICRMDRTMPADERRKIALFCNVEERAIVGSYDVDSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWKKIVHAIQNPKHTVKIAMVGKYVDLTESYKSLIEALKHAGIHTETDVQITFVDSENIEKNKGDVSMLKDMDAILVPGGFGSRGVEGKIAAVRYARENNVPYLGICLGMQIALIEYARDVAGLKGANSTEFDLKCAAPVVALIDEWQTADGSVETRDESTDLGGTMRLGAQEVELKAGSLAAKIYGSGHIRERHRHRYEVNNNYVPTLEQAGLVIGGVSAGRERLVETIELPNHPWFFACQFHPEFTSNPRKGHPLFTAFVKAALNNKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ILVI_ECOLI
Sequence: MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVTSDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEMWLSKTERT
What are the official names of this protein?
Acetolactate synthase isozyme 3 large subunit, AHAS-III, ALS-III, Acetohydroxy-acid synthase III large subunit.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: MCR_TUPBE
Sequence: METKGYHSRPEGLDMERRWGQVSQPVDRPSLGPAERTEENNYMEIVNVSCVSGAIPNNSTQGSSKEKQELLPCLQQDNTQSGILTSEIKTELEPKELSATVAESMGLYMDSVREADYAFEQHAQQGSLSPAKIYQNVEQLMKFYKENGHRSSTLSNVSRPSRSFLPDPGSAVNGGVMRAMVKSPILCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTVRFGSFPVHSPITQGTPLTCSPTVDNRGSRSHSPAHASNVGSPLSSPLSSMKSPISSPPSHCSVKSPVSSPNNVTLRSCVSSPANINNSRCSVSSPSKANNRSTLSSPAASTVGSICSPNAFSYPASGASVGSSATRDVIPSPDTHEKGAHEVPFPKTEEVENAISNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKIHSDSPFSSVPIKQESTKHSCSGASFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGFEGNCEGTGFPMGIKQEPDYGIYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHGDLSARKIDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDGASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGLHEEQPQQPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSSISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSRMCLSSFALSWRSYKHTNSQFFYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQFTFEEYTFMEVLLLLSTIPKDGLKSQAAFEEMRANYIKELRKMVTKCPNNSGQSWQGFYQLTKFLDSMHDLVSDLLEFCFYTFRELQALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
What is the function of this protein?
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol.  Binds to mineralocorticoid response elements (MRE) and transactivates target genes.  The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity).
What are the official names of this protein?
Mineralocorticoid receptor, MR, Nuclear receptor subfamily 3 group C member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic and nuclear in the absence of ligand, nuclear after ligand-binding.
Protein: PXPA_CAMJJ
Sequence: MFKVDLNSDLGESFGAYKMGMDEEILKFVSSVNVACGFHAGDPCVMDETLNLAKQNGVCIGAHPSYPDLLGFGRRNMQISFEEAKNYALYQLGALFGFAKAKGMKIQHFKAHGALYNMAAIDENLALALCEAVASFDENIIFLGLSNSAMNEAAKKKGLRYANEVFADRAYNDDGTLVSRKLEGALIHDENLAIKRVIKMIKESKVTSINGKEIDLKADSICVHGDNAKALEFVKKIKENLKKEQIQICALENFI
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: HPM1_YEAST
Sequence: MSFSFGFTSNDFDDDELVAQPETFVESSKENENTTAYINPLDSDFLSQAGVVQPNVEDLGTILESLKDVRLTFEEFQSPIYRKPLIKRELFDVKHQLMLETDAQSNNNSTELDILLGDTSEDLRKNIYEGGLKSWECSYDLVDLLSENVDRISNDIDAVVEIGCGTALPSEFLFRSALLRNDRSKGLKFVLTDYNASVLRLVTIPNLVITWAKTVLTKEQWYALQKDECEDIPINNEELLLTSKLLAAFYDDVQSRNISVTLISGSWGRKFSNLIHEVLSGSQKVLSLSSETIYQPDNLPVIAETILDIHNLPQTDVKTYVAAKDIYFGVGGSITEFEAYLDDKINSEHLPIHSERFKVNSGLKRSIICIETNKAIR
What is the function of this protein?
Protein-histidine N-methyltransferase that mediates methylation of RPL3 at 'His-243' (PubMed:20864530, PubMed:24865971).  Methylates ribosome-associated RPL3, but not free RPL3, thereby regulating 60S subunit assembly (PubMed:24865971, PubMed:26826131).  In addition to RPL3, mediates His methylation of other proteins (PubMed:26826131).
What are the official names of this protein?
Histidine protein methyltransferase 1, Mitotic exit network interactor 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y8252_DICDI
Sequence: MIPQSVINFKIECCFFVKIEDESLNKLLNLTKLSFINAPVIPLLTINTLPPNLEILELTLGKHKVLIIVFQKV
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289089.
Protein: VM2H1_BOTLA
Sequence: MIQVLLVTICLAALPYQGSSIILESGNVNDYEVVYPRKVTALPKGAGQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSETHYSSDGRKITTNPPVEDHCYYHGRIENDADSTGSISACNGLKGHFKLQGEMYLIEPLKLSDSEAHAIYKYENVEKEDEAPKMCGVTETNWESYEPIKKASQSNLTPEQQRFNPFKYVELVIVADHRMFTKYNGDLEKIRIKIYEIVNILNEMFRYLYIRIALVDLEIWSNRDLINVTSVAGDTLDSFGNWRETDLLKRKSHDNAQLLTGIDFNGTTIGIAYIASMCNPYLSVGIVQDHSEINFLIAVTMAHEMGHNLGMRHDTDYCTCGGYSCIMCAVLSDQPSKFFSNCSYIQYGKFIMNQNSQCILNEPLGTDIVSPPVCGNEILEVGEECDCGCPTNCQDPCCNAATCKQYSWVQCESGECCEQCRFRAAGTVCRRATDNDMDNRCTGQSADCPSNG
What is the function of this protein?
Snake venom zinc metalloprotease-disintegrin that hydrolyzes azocasein, gelatin and fibrinogen (Aalpha and Bbeta chains and partially gamma-chain), and exerts a potent local and systemic hemorrhagic activity in mice.  It inhibits ADP- and collagen-induced human platelet aggregation (IC(50) = 0. 3 uM and 0. 7 uM for ADP and collagen, respectively).  This inhibition is dependent of protease activity, and probably occurs through the degradation of an unknown platelet receptor.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin BlatH1, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APT_RHIL3
Sequence: MNNTISELAASIRSIPDYPKPGIIFRDITTLLGNPRAFRRAVDELVQPYAGTKIDKIAGMEARGFILGGAVAHQLSSGFVPIRKKGKLPHETVRIAYSLEYGVDEMEMHRDAVQPGEKVILVDDLIATGGTAVGATRLLRQIGAEVVGACFVIDLPDLGGRRKLEELGVVVHTLVEFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METF_SALTY
Sequence: MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFEGLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
What is the function of this protein?
Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.  Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate.
What are the official names of this protein?
5,10-methylenetetrahydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the methylenetetrahydrofolate reductase family.
Protein: NMT_SCHPO
Sequence: MDNENNKNTKNSQQDSSFSEGGIRELLDRLALRSLIEKEEAAAPPKTYEDFKFWKTQPVPKFDDECTQEGPIDPNTDINQVPREPYRLLKEFEWATIDVTNDNELSEVHELLTENYVEDATAMLRFAYISEFLRWALMPPGYVKEWHVGVRVKSSRKLVAFISAVPLSIRVRDKIIKKCAEVNFLCIHKKLRSKRLTPLLIKEVTRRCHLENVWQAVYTAGVLLPSPVSLSRYMHRSLNWKKLYDIGFAPFPLGSTEKKETAKYHLPPNTQTPGLRPMELKDVPAVQSLLSQYMERFELAHLFSEEEVRHWFLYTDKVSSGPVVWSYVVENPESKKITDFFSFYSLPSTVIGNPKYKDIQAAYLYYYASDSCPKDLSSESQLAFVERCKLIVNDALILAKKFHFDVFNAVTVLDNNLFLKDLKFGEGDGFLNYYIYNYNCPKIPGGIDASKSVDYSRPSGMGFVMI
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRA_HUMAN
Sequence: MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK
What is the function of this protein?
Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
What are the official names of this protein?
Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling, STARS.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines.
Protein: PNP_STRA3
Sequence: MSKQVFEMIFAGKKLVVETGQVAKQANGSVVVRYGDSTVLTAAVMSKKMSTGDFFPLQVNYEEKMYAAGKFPGGFNKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSFDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVAYVDGNFIINPTAQEQEASALELTVAGTKEAINMVESGAKELSEEIMLEALLKGHEAVCELIAFQEEIVTAIGKEKAEVELLQVDPELQAEIIATHNIALQAAVQVEEKKAREAATEAVKEVVIGEYEARYAEHEEYDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLDAVIDFLPQVHGSGLFTRGQTQALSVLTLAPMGEAQIIDGLTPEYKKRFMHHYNFPQYSVGETGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIEGITPQILEEALAQAKKARFEILDVLHGAIAEPRPQLAPTAPKIDMIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIFSSDQAAIDRTKDIIASLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTANVADVLEIGEEVDVKVIKIDDKGRVDASMKALLPRPPKADNPKKES
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTB_SHISS
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFTNMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDQGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTEITPGLAALDTIRLTSSDGGVVPLSSIAKVEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQEIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_LACPL
Sequence: MALDLKKYVASIPDYPEPGIIFRDISPLMADGEAYREATDQIVQFARDKHVDMIVGPEARGFIVGCPVAYELGVGFAPARKKGKLPRETVKATYDLEYGQSALYLHKDAIKPGQNVLVTDDLLATGGTISATIQMVEELGGNVVGTAFLVELKELHGRDKIKDYDMLSLMQF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOC1_MOUSE
Sequence: MRLFIALPVLIVVVAMTLEGPAPAQAAPDLSGTLESIPDKLKEFGNTLEDKARAAIEHIKQKEILTKTRAWFSEAFGKVKEKLKTTFS
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein (By similarity).  Binds free fatty acids and reduces their intracellular esterification.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_CHLFF
Sequence: MKLLTASVTPFLPNYDIDFLSVEKLLHSQEKEGNGVVLLGSTGESLALTVQEKEKLVAYACSLDLKIPIIVGVPGTSLHEASAWVSLCQSYPVDGFLITSPIYTKPGIQGQILWFESILNITNKPAILYNIPSRAGSPIYLETVRALSGHPFFYGIKDSGGSIDRCREYTQVCPNLIIYCGDDGLWPQMHQCGARGLISVLSNSWPKEAHNYVEDPFNKNNSLLWCELVSWINQTTNPISIKAMLAYKQDIAYDILRLPLSIKDLQNKKVLPVLVEKMSQWSQICECVFT
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.