PharMolix/UniProtQA huggingface dataset:
Protein: MARK2_HUMAN
Sequence: MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
What is the function of this protein?
Serine/threonine-protein kinase (PubMed:23666762).  Involved in cell polarity and microtubule dynamics regulation.  Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 and RAB11FIP2.  Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762).  Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly.  Regulates epithelial cell polarity by phosphorylating RAB11FIP2.  Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX.  Regulates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtubule-dependent accumulation of KIF13B.  Also required for neurite outgrowth and establishment of neuronal polarity.  Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.  Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).  Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery.  Essential for the asymmetric development of membrane domains of polarized epithelial cells.
What are the official names of this protein?
Serine/threonine-protein kinase MARK2, ELKL motif kinase 1, EMK-1, MAP/microtubule affinity-regulating kinase 2, PAR1 homolog, PAR1 homolog b, Par-1b, Par1b.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Lateral cell membrane. Cytoplasm, cytoskeleton. Cell projection, dendrite. Cytoplasm. Note=Phosphorylation at Thr-596 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm.
Protein: PITH1_DROME
Sequence: MPHGHSHDHGGCSHEASDVDHALEMGIEYSLYTKIDLDNVECLNEETDGQGKSVFKPYEKRQDLSKYVESDADEELLFNIPFTGNIKLKGIIISGANDDSHPNMVKIFKNRPRMTFDDARAKPDQEFQLTRDARGEIEYSPKVVTFSSVHHLSLYFPSNFGEDITRIYYIGLRGEFTEAHYHGVTICNYESRANAADHKEKAFDGVGRAIQ
What are the official names of this protein?
PITH domain-containing protein CG6153.
What is the protein family that this protein belongs to?
Belongs to the PITHD1 family.
Protein: CCHL_CAEEL
Sequence: MGSSQSTPKVQDANADAERIRKAQHSMAAAGGGSQCPLTPEQRAAASGENCGAGGACPVGADKASINPLNNELEHPNQKPAPDQPFALPTKREKSTIPKAGTETETWTYPSPQMFWNAMLKKGWRWQDDSLSKSDMENIISIHNANNEEAWREVLKWENLLHPECAEPKLKSFKGDAKNLSPRARFRNLFLGYDLPFDRHDWIVDRCGTKQVQYVIDYYDGGAVDPSSKLFTILDVRPAVNDIGNIWDRMVVAYWRFKFETLGFTPSLPIPPTEGHNVNH
What is the function of this protein?
Probable lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
What are the official names of this protein?
Probable holocytochrome-c-type synthase, Cytochrome c-type heme lyase, CCHL.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-type heme lyase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: TNPO1_ORYSJ
Sequence: MAAAAALWQPQEEGLREICTLLDAHISPNSDQARIWQQLQHYSQFPDFNNYLVFLLARGEGKSFEARQAAGLLLKNNLRATFSSMPPASQQYVKSELLPCIGATNKAIRSTVGTVISVLFQIVRVAGWIELFQALHQCLDSNDLDHMEGAMDAIYKICEDVPEELDVDVPGLPERPINVFMPRLLQFFQSTHAILRKLALGCINQYIVVMPAALYMSMDQYLQGLFNLAKDPSADVRKLVCSAWVQLIEVRPSILEPHLKNVTELMLQANKDSDDEVALEACEFWSAYCDVSMPPEGLREFLPRLIPTLLSNMSYSDDDESLADAEEDESFPDRDQDLKPRFHASRLHGSETGEDDDDDDAVNVWNLRKCSAAGLDVLSNVFGDDILPTLMPLIQQNLARTDDDAWKEREAAVLSIGAIAEGCITGLYPHLPQIVAFLIPLLDDKFPLIRSITCWTLSRYSKFIVQSLEHPNGREQFDKILLGLLRRVLDTNKRVQEAACSAFATLEEEAAEELVPHLGIILQHLMCAYGKYQRRNLRILYDALGTLADAVGAELNQAKYLDIFMPPLITKWQQLANSDKDLFPLLECFTSIAQALGPGFSQFAEPVFQRCINLIQSQHLAKVDPAAAGALYDKEFIVCALDLLSGLAEGLGAGIESLVSQSSLRDILLQCCMDEAADVRQSALALLGDLSRVCPIHLHPRLQEFLNVAAKQLNPQCVKEAVSVANNACWAIGELAIKIGKEISPVVITVVSCLVPILKSPEGLNKSLLENSAITLGRLCWVCPDIVAPHMDHFMQAWCNALCMIRDDFEKEDAFHGLCAMVAANPTGAVGSLTFICQACASWNEIKSEGLHNEVCQILNGYKQMLGSGGWEQCMSTLEPAVVQRLGRYGV
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for nuclear localization signals (NLS) in cargo substrates.  Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Transportin-1, OsTRN1, Importin beta-2, Karyopherin beta-2.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Shuttles continuously between the nucleus and the cytoplasm.
Protein: PURA_EHRRG
Sequence: MTNIVVVGLQWGDEGKGKVVDWLSNNADAVVRFQGGNNAGHTIVIQEKTYKLNLLPSSILHNNKLSIIGNGVVLDPYALMSEIDNLRINGININTQNLVISESCPLVLNIHKEADTLFEQLRQNTIGTTNKGIGPCYADKISRRALRVCDLFDKKDILYNKVNNLLNYHNLLRQNFNILPIEASKLVDELLDIAPKILPFVKPVWKVIHDLTQQNKTIIFEGAQGTFLDIDHGTYPFVTSSNTIAPQAFVGGGINLSHSSCILGVIKAYTTRVGNGPFFTEQKNEIGKSMFERGNEIGTVSNRERRCGWFDAVLAKQAIILSGVSGLVLTKLDVLDQFSEIKICTQYKYDGVIYDYIPASSYVQNNLEPIYETVPGWKENTFGSVTYEDLPKNAISYIKKIEEILKVPVYLISTGPERNAMIIINDKFLK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_THEMA
Sequence: MGNTVAMILAGGQGTRLGVLTERIAKPAVPFGGKYRLIDFTLSNCVNSGIYRVGVLTQYRPHVLSKHIGIGRPWDLDRKDGGVEILPPYVGRHESDWYKGTANAVYQNLEFLEENDAELVLILSGDHVYAMNYNDLIDYHLLKEADGTIACMEVPIEEASRFGIMITDVDGRIVDFEEKPAKPRSNLASLGIYVFNYEFLKKVLIEDENDPNSSHDFGKDVIPRILRENLGSLYAFRFDGYWRDVGTLRSYWEANLELVLPVPPFNLYDPNWRFFTHTEEMPPAYVAPGSKVSTSLVSEGAEVYGNVFNSVIFQGVKIGRGTVVKNSVIMTRTEIGENCYLENVIIAENVKIGSNVRMGVGEDAESKLDPKVYSGLLTVVGMNSVIPDDMVIGKNCVIGIGVRPEDFKSKTLESGDYVIVREE
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: RS6_STRU0
Sequence: MAKYEILYIIRPNIEEEAKNALVSRFDSILTDNGATIVESKDWEKRRLAYEINDFREGLYHIVNVESEDAVALNEFDRLAKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ATPL_HELPY
Sequence: MKFLALFFLALVGVAFAHDGGMGGMDMIKSYSILGAMIGLGIAAFGGAIGMGNAAAATITGTARNPGVGGKLLTTMFVAMAMIEAQVIYTLVFAIIAIYSNPFLS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLNA_CRYNJ
Sequence: MSQLIATKRVDLLAPYLALDQGSRVQAEYIWIDAEGGIRSKTMTLDKAPSSVADLKEWNFDGSSTNQAPADNSDVFLRPVAIFKDPFRGGANILVLCECYDNDGTPNKSNYRAHCKKVMDAAKDTEPWFGLEQEYTLFDADGQVFGWPKNGFPGPQGPYYCGVGAGKVFARDFIEAHYRACLYAGIKISGINAEVMPSQWEFQVGPCTGIEMGDHLWMARFLLLRIGEEWGITPSLHPKPLKGDWNGAGCHSNYSTKDMRTPGKGMAAIEDAIKKLEKKHLEHIAVYGEDNDLRLTGKHETASMTTFSAGVANRGASIRIPRHVGAQGYGYLEDRRPASNVDPYRVTAILVETTVLNN
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STIP2_ARATH
Sequence: MGDEGKKEKRRQTKEDAVYGFVFESDSNSDDSGGSRRKKRRKTKPVKFSSAGNIDQVLKQNRGNCKIDENDDTILPIALGKKIADKAHVREKNNKKENFEKFSGGIGMKLLEKMGYKGRGLGKNQQGIVAPIEVQLRPKNMGMGYNDFKEKNAPLFPCLNKVEEKKKSVVVTVSENHGDGRRDLWKKKNVRKEVYITAEEFLGKKQEEGFGCDQLIIDKRGPQDRVVNSLRNLYAEEKATDANVQQPELQHNLRFIVKSLEHGILKTDKDLRNEKGLALSLQQEKEKFKMGVKKQKTLFDNLGYVAEEIDRIEVEIASGNLTLDSLANRFKDLRSSYPDDYKCCNLSCIASSLALPLFIRMFQGWDPLSDAEHGIEAISSWKMLLEVEDNQSISTPYSQLVSEVILPAVRVSGINTWEPRDPEPMLRLLETWEKMLPSLIFETILTTVVLPKLSIAIESWEPRLETVPIHFWVHPWLPVLGQKLESAYQIIRMKFGNLLDAWHPSDVSVHTILSPWKTVFDAASWEQLMRRYIVPKLQVALQEFQINPADQNLDEFNLVMGWVSSVPIHLMTDLMERFFFPKWLDVLYHWLCSEPKFDEIMKWFLGWKGTFPQELSANRRIEIQFKRGLDMAREAVERMEMSQPGARENISYHKAQEQRQSEGRAKVQAQVDDPEELSFKEAVELFAQEKELLLKPKPHRMHNGLQIYRFGNVSVLLDSANSKLLAQEEGRWFPVDLDSLLKMHYSAVTGKQ
What is the function of this protein?
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
What are the official names of this protein?
Septin and tuftelin-interacting protein 1 homolog 2, Protein SPLICEOSOMAL TIMEKEEPER LOCUS 2.
What is the protein family that this protein belongs to?
Belongs to the TFP11/STIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VEMP_CVPR8
Sequence: MTFPRALTVIDDNGMVISIIFWFLLIIILILLSIALLNIIKLCMVCCNLGRTVIIVPVQHAYDAYKNFMRIKAYNPDGALLV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: RS16_PSYWF
Sequence: MVVIRLARGGAKKRPFYQVVVADQRRSRDGRYIENLGFYNPLAKGQEVELRLDMDAYNAWIEKGAQPSDRVKALAKGYKPTTEEATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y568_ENT38
Sequence: MLILISPAKTLDYQSPLATERYTQPELLDHSQQLIREARKLSAPQIGKLMSISDKLADLNATRFHDWQPDFTPKNARQAILAFKGDVYTGLQAEEFSEADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENAKGKDLYQFWGDIITEKLNDALKAQGDNIVINLASDEYYRSVKPKKLNAEIIKPVFLDEKKGKFKVISFYAKKARGLMSRYIIENRLTKPEQLTAFNSEGYFFDGDASEKGELVFKRHEQ
What are the official names of this protein?
UPF0246 protein Ent638_0568.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RPIA_SYNPW
Sequence: MSDLQNQMKQAVADAAVQQFRDGMVVGLGSGSTAALMIKGLGERLAAGQLSDIVGVTTSFQGEVLAAELGIPLRSLNAVDRIDLAIDGADEVDPAFQLIKGGGACHVQEKLVAARADRFIVVVDSTKLVERLNLGFLLPVEVLPGAWVQISQQLKAMGGDAELRMATRKAGPVVTDQGNLVLDVRFEGGIADPASLEKEINNIPGVLENGLFVNLADEVLVGQIDGGVASARSLEKAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PSBE_PARMW
Sequence: MAAGSTGERPFFEIITSIRYWVIHFVTLPSIFLAGFLFVSTGLAYDAFGTPRPDAYFQASESKAPVVSQRYEGKSELDVRLK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DNLJ_SODGM
Sequence: MEQIEQHILRLRKQLRHWEYLYYVEAAPEVPDSEYDRFMAELRTLEAERPDLLTADSPSQRVGGQAQSSFGQVRHEVPMLSLDNVFEEPGFLAFDKRVRDRLKRDDDMTYCCELKLDGLAVSLLYENGELVRAATRGDGATGEDITANVRTIRTIPLRLQDHDNLPRLLEIRGEVFMSEAGFLRLNETAKREGSKVFANPRNAAAGSLRQLDPSITARRPLTFYCYGVGLLEDGELPESHWERLQQFKAWGVPVSDRVRRCTGSAAVLDFYRQVHEARLSLGFDIDGVVIKVDSLALQQRLGFVARAPRWAIAYKFPAQEQLTRVRDVEFQVGRTGAITPVARLEPVLVSGAMVSNATLHNADEVERLGLMIGDTVIVRRAGDVIPQIVGVVTSERPAEVRPVAFPTQCPVCSSDVERVEGEAVLRCTAGLVCAAQRKEALKHFVSRRAMDIDGMGDKIIDQLVERELVKTPADLFRLNKEILTRLDRMGSKSAQNLLEALEKARQTTFARFLYALGIREVGEATAVNLAAAYGTLDALIAADIDSLTGVQDIGNIVATHVRHFFEETHNIEVIQDLLSPAIGIRWPEPVAAPVAASDNPFAGKTIVLTGSLSSLSRDEAKDHLVALGARVSGSVSAKTDLLIAGEAAGSKLSKAQQLNIPVMDEAEMMRLLGESSDA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL23_ENDTX
Sequence: MDIRNIIKRPIVTEKAVLMKEKSNKYTFVVDKSANKFQIKYAVETLFNVKVKSVHTSNCVGKSLKVGRYAAGYRSDWKKAIVKLGKGQEIQLADKV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EFTS_BARQU
Sequence: MSITAAQVKELRELSGAGMMDCKAALADTNGDMEAAVDWLRKKGIAKADKKAGRTAAEGLIGIVSKDTSAVLVEINSETDFVARNDLFQDIVRNVATAALDTQGNVESVSASFYPGSEKTVEATIKDAISTIGENMTFRRSAKLSVKDGVVATYIHSKVAEGLGKLGVLVAVETTGNKEAAAVFGRQVAMHIAATNPLALTAEDVDSGAVEREKAIFSDQARQSGKPENIIEKMVEGRLRKFFEEVVLLSQAFVMNPDITVEAALKDAEKSIGAPARITGFIRFALGEGVEKKESNFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STRPB
Sequence: MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: UBIX_SACS2
Sequence: MVKEAGTKNRREKTKRIIIGISGASGTIYGIRTVQFLNELGYEIHIIISKSAEKVAQKELGINLINELKKYSSYIYNQSQIEASPSSSSFSITSKGMIIIPCSIKTLAEIANGIGSNLLSRTALNFIRTNKRLVLVIRETPLGAIELENALKLARLGVYIMPASPAFYILPKNIDDMINFIVGKALDLLGIKHDIYKRWKG
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: ZN425_HUMAN
Sequence: MAEPASVTVTFDDVALYFSEQEWEILEKWQKQMYKQEMKTNYETLDSLGYAFSKPDLITWMEQGRMLLISEQGCLDKTRRTTSPPTDEQLNMKNTGKLLCFDDEGTPRTKEEDCRLNGPQKQDLCAALRGKERKILLAQTATFQSPSLRETEILNKKVSITAYDPDKKDLRHKPRETPGRLEIPTGPRCYSCYVCRKVFQVRRDLLKHKRSHSKSQLCRYPKYKNSSRGKSELRRTQRLLCQKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKEKPSSL
What is the function of this protein?
Acts as a transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 425.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly expressed in the nucleus.
Protein: RS17_NITWN
Sequence: MPKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYKKTIRRSKNYHAHDENNEFKPGDMVWIEESKPISKLKRWTVVRGEQRKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: UREE_HALH5
Sequence: MYVHSVIGNIEAKTPTKTIEWIELDWDELNKRILRKTTDHGREVAIVMEEQGLTFGDILYEGEDVAIAVRTKLEPAFVIRPKTMKEMGKTAFELGNRHTPCLVENDEIYVRYDSTLAALFNEIGVNYEQTEKRFKQPFKYKGHHHHHD
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
Protein: LEXA_MARMM
Sequence: MLTRKQNELLLFIHNRIKETGVSPSFDEMKGALQLASKSGVHRLITALEERGFIRRLAHRARALEVLKLPESAAAHETPAIPKGDLGANVVRGNFAKPEPDARENTVDIPMLGRIAAGVPISAIQHETDRFPVPADMVMGGEHFGLEVKGDSMIEAGIMDGDTVLIRRCQSAETGDIVVALIDDEEATLKRLRKKGGSVALEAANPEYETRIFPPDRVKVQGRLVGLIRRYH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL9_SYNPW
Sequence: MAKRVQVVLNEDVLSLGRDGDMVEVAPGYARNFLLPYGKAVPVTPAVMKQVEHRRAKEAERQAALKQEALAFRTALDTIGRFTVKKQTGDDDVLFGTVTNGDVAEVIEEATKKEVDRRDITVPDIHRTGNYKVSVKLHSEVTAEINLEVVSY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SCPB_MESM1
Sequence: MNNKIIEALIYIQGEEGLSSEQLQKVLKSESISSARALLKVFKEKWNNEQHGIKVEEFNDVYKFATIKDVKDYVSELVTIIKKQRLSNAAIEVAGIVAYKQPISKSQINKIRGVASEIVVNTLLIKGIIEEVGIAQTPGNPILYGVTAKFYDYFKIKSLHELPNLKEFDDTGEYESIEDFDLYSSQREDQDE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
Protein: P4R3B_MOUSE
Sequence: MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPACELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDVLLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNTTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDDEEGKAVITPVEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRASSGGFKFTFSHSPSATNGTNSTNSKSVVSQTTPASSNVASSKTTSLATSVTATKGNLVGLVDYPDDEEEDEEEESSPRKRPRLGS
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).  May regulate the activity of PPP4C at centrosomal microtubule organizing centers (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 3B, SMEK homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SMEK family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.