PharMolix/UniProtQA huggingface dataset:
Protein: TRPM4_HUMAN
Sequence: MVVPEKEQSWIPKIFKKKTCTTFIVDSTDPGGTLCQCGRPRTAHPAVAMEDAFGAAVVTVWDSDAHTTEKPTDAYGELDFTGAGRKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSAGTKAPALKGGAAELRPPDVGHVLRMLLGKMCAPRYPSGGAWDPHPGQGFGESMYLLSDKATSPLSLDAGLGQAPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRKSEEEPTREELEFDMDSVINGEGPVGTADPAEKTPLGVPRQSGRPGCCGGRCGGRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGGGGSLASGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRSPQPSSPALEHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVLEREVQQCSRVLGWVAEALSRSALLPPGGPPPPDLPGSKD
What is the function of this protein?
Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:29211723, PubMed:30528822).  While it is activated by increase in intracellular Ca(2+), it is impermeable to it (PubMed:12015988).  Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane.  It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc.  Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.  Involved in myogenic constriction of cerebral arteries.  Controls insulin secretion in pancreatic beta-cells.  May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload.  Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization.  Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.  Plays a role in keratinocyte differentiation (PubMed:30528822).
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 4, hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC-4, LTrpC4, Melastatin-4.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM4 sub-subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane. Endoplasmic reticulum. Golgi apparatus.
Protein: MLTF_HAES1
Sequence: MKGLFIRIVLAICLSLWAIDMVFPWQQIVRSKQNYHTTIQERQKLIVGTINNPVSYFIGTNGETGLEYELSKAFANYLNVDLEMFPLNSADALFQALAQGKIDIAAASLFYQQDRSEKFKLGPAYHAASWQLTYRKGERRPITLENLSGKLVIPANSALNNILLAKKEKYPSLTWETSELSQEELLFQVAEGKIDYTIATSTEVSVNQQIKPQIAIAFNVTDEFTVHWYLSDKGSSELQAALLDFMNSAIENGLIARIEEKYFNHLNQFDYVDTRSYLNAIETVLPKYAPLFEKYKGDLDWRLLAAISYQESHWNPEATSPTGVRGMMMLTKATADRMNITNRLDPEQSIKAGSEYLHLLLKQMPDTILKEDRIWFALAAYNMGLGHLLDVRRLTKQLGGNPDNWLEVKKNLPLLAQKRYFTHLKYGYARGYEAFQYVENIRRYMNSIMNYYRLQQNQQDRQDRYENENNDVISTQTQQEQR
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: AHPD_BRUAB
Sequence: MSIDDLKSKIPDFAKDVRLNLSSMASDETLTPQQKYGLFVACGIASRNADVRKALVAEAAGKVDASVIQAAKAAASIMGMNNVYYRFVHLASNKDYRTMPARLRMNVISNPGVDKIDFELWSLAVSAINGCGMCIDAHEDVLRKANVTAEAIQAAVRFASIIQSAAIALEAADTE
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: RL11B_BACCR
Sequence: MAKKVLKVVKIQLPAGKANPAPPVGTVLGPTGVNIMMVCKEYNALTQGQAGMIIPAEITIYEDRSFSMKIKTAPVAELLKREAGISKGSGEPNKSKIGSITEEKLREIAEYKFPDMNAASVEAAMRTIEGTARSMGITVQK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11-2/L11-3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CDC62_METAC
Sequence: MTGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALRPSLRGMRPLNCLLVGPPGTGKTSAVMKVFREVEVHAPGVVAVKVNCQIDSTRFAVISRIYRQLFGISPPNSGIAFRKLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSLLRAHEQYPGAKIGVIGIVNDASDLYCLDSRVNSVFLPEEISFLRYGEAEILDILKDRVKYGFYPKVISDDVLELVVSYVEKTGDLRVGIDLLRRSGFNAERRGSRTISSGDVEKAYEASKLLHLCRGISLLSDSEKQLLELIAKADDVKAGELYKSFHELTQLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKAKYEAEDILNCLKKG
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 2.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: MIAA_ORITB
Sequence: MNDVFIIAGPTASGKSELAMLLAQKFNGVIINADSMQIYKEIPIITASPSISEKKQVDHYLYNYVSIFHSDINELNSFDNISQSKVNANYNNINLQQSITKHLTDRRYSVAQYVQEACKIIRSVIHALKLPIVVGGSGMYIKALVYGIHHIPEITCEIRMQVQDLYKKLTKQEFYQKLIDLDPISKNYIHSSDAQRMIRAYEVALQTNKSIFSYHNSKLVSPLECYNVKKIILLPDRQLLYQNCNQRFAKLATNGELVDEITKIKPYYDHISISAKKALGINEIISYLNQELTIEEAITIAQQKIRQYAKRQLTWFRNQTINGYTLHYQSMSELYKAQVNDVFFN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: LCFCS_THET8
Sequence: MEGERMNAFPSTMMDEELNLWDFLERAAALFGRKEVVSRLHTGEVHRTTYAEVYQRARRLMGGLRALGVGVGDRVATLGFNHFRHLEAYFAVPGMGAVLHTANPRLSPKEIAYILNHAEDKVLLFDPNLLPLVEAIRGELKTVQHFVVMDEKAPEGYLAYEEALGEEADPVRVPERAACGMAYTTGTTGLPKGVVYSHRALVLHSLAASLVDGTALSEKDVVLPVVPMFHVNAWCLPYAATLVGAKQVLPGPRLDPASLVELFDGEGVTFTAGVPTVWLALADYLESTGHRLKTLRRLVVGGSAAPRSLIARFERMGVEVRQGYGLTETSPVVVQNFVKSHLESLSEEEKLTLKAKTGLPIPLVRLRVADEEGRPVPKDGKALGEVQLKGPWITGGYYGNEEATRSALTPDGFFRTGDIAVWDEEGYVEIKDRLKDLIKSGGEWISSVDLENALMGHPKVKEAAVVAIPHPKWQERPLAVVVPRGEKPTPEELNEHLLKAGFAKWQLPDAYVFAEEIPRTSAGKFLKRALREQYKNYYGGA
What is the function of this protein?
Catalyzes the esterification of a number of long chain fatty acids with CoA, resulting in the formation of long-chain fatty acyl-CoA.  Myristate (C14) is the most efficiently processed fatty acid, followed by palmitate (C16).  Also catalyzes the esterification of stearate (C18) and laurate (C12), but at lower efficiency.  Does not catalyze the esterification of the unsaturated fatty acids mysteroleic and palmitoleic acids in vitro.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase, Long-chain fatty acyl-CoA synthetase, LC-FACS.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CMAH_MOUSE
Sequence: MMDRKQTAETLLTLSPAEVANLKEGINFFRNKTTGKEYILYKEKDHLKACKNLCKHQGGLFMKDIEDLDGRSVKCTKHNWKLDVSTMKYINPPGSFCQDELVIEMDENNGLSLVELNPPNPWDSDPRSPEELAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCKADLIYISHMHSDHLSYPTLKQLSQRRPDIPIYVGDTERPVFWNLDQSGVGLTNINVVPFGIWQQVDKSLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPEKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKAERRKLLNYKAQLVKDLQPRIYCPFAGYFVESHPSDKYIKETNTKNDPNQLNNLIRKNSDVVTWTPRPGAVLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFGPYLEILNSAVRDEIFCHSSWIKEYFTWAGFKNYNLVVRMIETDEDFSPFPGGYDYLVDFLDLSFPKERPSREHPYEEIHSRVDVIRYVVKNGLLWDDLYIGFQTRLLRDPDIYHHLFWNHFQIKLPLTPPNWKSFLMHCD
What is the function of this protein?
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions.  Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
What are the official names of this protein?
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminate monooxygenase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the CMP-Neu5Ac hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum.
Protein: A1OB2_LOXVA
Sequence: WIMGHMVNNIKQIDEFVNLGSNAIETDVSFDKKANPEYTYHGTPCDCGRDCLRWEYFNDFVKALRTATTPGNSKYDKLFLVVFDLKTSSLYDYRASEAGTKLAKNLLQHYWNNGNNGGRAYIILSIPNLKHYKLITGFQQTLKDEGHAELLDKVGYDFSGNDDIGDVQKTYEKAGVTGHVWQSDGITNCLLRGFTRINAAVANRDSANGIINKVYYWTVDKRQATRDTLDANVDGIMTNYPDITVEILNEDAYKTKFRIATYEDNPWETFKE
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LvSicTox-alphaIC1bii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGB_RICPU
Sequence: MSELLLELFSEEIPAFMQKNAEEGYLNIFTKIFEENEIFAKVQVFAGPRRITLHATHLPKITLPKEEEIKGPSIEAPETAINGFCKAHNVSKLELPTKLISNQLYYFFVKKTEEREIKEILPEIIIEAINKYSWAKSMFWGDYKIKWIRPLRNILCIFNGEILPMQFGHLTANNITYGHRLTDNKKLEVTDFEDYRNKLLENHVILERAKREAIIKTGLLELANSHELIIKEDNRLVEEVVGLSEFPIVLLGKIPQKFLELPKEVLISSMRTHQKYFCLFDKTGNFTPYFLFVSNGRFTNAELVIQGNEKVLSARLSDALYFCKQDIAKTLESRLGQLEAVTFHAKLGNLREKIERITDICNYIAPNNKDLITAARLCKSDLVSEMVWEFPDLQGIMGYYYAKHEGLNAEIAAAIKDHYKPQGLSDNVPSGNAALLALADKLDSLVGLMIAGETPTGSGDPYALRRQALGIIRIILENKLELNFNDLINFSINLYKDSSDENKNLIISFFEERAKFYFKNDYDIALINAVLDLNLIDTNFKLDELKEFLIEDAGKQLLNAYKRASNIIGDQKITGLVDASLFSTQPEKELFEVIQKISPEIIDSIADKDYKKALNLLSSLLTPITSFFDNILVNDSDPKIAQNRLSLLQNICELFDKVAKFNRL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y444_BORPA
Sequence: MSGYFVLKASGTQYMFNLHAGNHEIILTSERYTSKASAQDGIASVQKNAPDDARYQRLTAKDGSPYFSLTATNGQSIGRSEMYKTTQARDNGIASVKSNAPGAPTKDQTQA
What are the official names of this protein?
UPF0339 protein BPP0444.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family. Duplicated subfamily.
Protein: RL17_RICPR
Sequence: MRHRIKGRRLNVTSSHRQSMLANMAVSLVIHEQIKTTLPKAKELRPYIEALITKAKKPDLAVRRSVLSKIKDKRAVEKIINILGVRYKDRPGGYTRIVKSGFRYGDLAPIAYIEFVDRDINAKGNVHQDANEEIKN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ATL56_ARATH
Sequence: MPPTNNYRISGEPPSTTPSHPPPKPKTRILSLFLVGVIMFSIFFLFLVLIGIASVLILPLLLSSLHRHHRRRRRNRRQESSDGLSSRFVKKLPQFKFSEPSTYTRYESDCVVCFDGFRQGQWCRNLPGCGHVFHRKCVDTWLLKASTCPICRARVRLWEEDPQEGELWRCFGHRRSSLLDL
What are the official names of this protein?
RING-H2 finger protein ATL56, RING-type E3 ubiquitin transferase ATL56.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CST1_CAEEL
Sequence: MPPSTDSSRRNSEEGSSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLMIQDAQEKAILGQAPMAASSGNDATLLSEGMSTMIDGGESTLVQHKDNYVTAQSLRSQMESLRIGGEIPKSAYIPGSSKNGNSPRVQPPGHTASASDPSKNQPFAQDGTGPNFQLGTSESSYKDASYNMMNTEAEYENRFQRAVVDGDFEFLRNITLDELIRRKESLDSEMEEEIRELQRRYKTKRQPILDVIEIKKRLQ
What is the function of this protein?
Serine/threonine-protein kinase which extends lifespan and delays tissue aging, probably by activating daf-16.
What are the official names of this protein?
Serine/threonine-protein kinase cst-1, STE20-like kinase 1, STE20-like kinase MST, cMST.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: HFQ_CHRVO
Sequence: MSSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAISTVVPARPVNIPHEHPAQKQEQAQDA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RECR_SODGM
Sequence: MQTSPLLEALTEALRCLPGVGPKSAQRMVFHLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQPVCTICANPRRQQSGQICVVESPADIHAIEQTGQFAGSYFVLMGHLSPLDGIGPDDIGLGRLQERLENESIEEVILATNPTVEGEATANYIAEMCAHYGVMASRIAHGVPVGGELEMVDGTTLSHSLAGRHPIKF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: Y1615_PYRAB
Sequence: MKLKGKGVGKNIVEGEVIVSKKPLSFLGGVDPETGIIIDPDSDIKGESIEGKILVFPKGRGSTVGSYVIYALSRNGKAPKAIIVEEAEPIVTVGAIISGIPLIAGVDISKLRTGMKVRINPRTGEVEIIG
What are the official names of this protein?
UPF0107 protein PYRAB16150.
What is the protein family that this protein belongs to?
Belongs to the UPF0107 family.
Protein: PYRR_PELTS
Sequence: MAREKAQILDKDGIRRSLTRIAHEIIERNKGTGNLVLVGIRRRGVPLAERLAGRIKDIEGRTVPVGILDITLYRDDLTTLAHQPVVRSTEVPFSVSGKIVVLVDDVIYTGRTVRAALDAIMDLGRPKLIQLAVLIDRGHRELPIRADYVGKNVPTSSREEVSVRLQEIDGEERVVILETAE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: OPSD_MESBI
Sequence: MNGTEGLNFYVPFSNHTGVVRSPFEYPQYYLAEPWQFSVLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVANLFMVLGGFTTTLYTSMHAYFIFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWIMALACAAPPLVGWSRYIPEGMQCSCGVDYYTPSPEVNNESFVVYMFVVHFSIPMVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVVIMVVAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPSFFAKSSAIYNPVIYIMMNKQFRNCMLTTLCCGRNPLGDDEVSTTASKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: RL5_SALHS
Sequence: MAKLHDYYKDEVVNKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TILS_PSELT
Sequence: MPLDEFEFSVLKTIQTHHLIFPGHKVLVALSGGMDSMSLLNILLKLRQKLNCEIFAAHLNHMIRENAIRDEQFVYSYCKKAGVKIFVERFDVPKFCADRKIGIEEGARAARYTFLNRIAHENGIDLIALAHNLNDLVETILYRIVRGTGLSGIVCMKLKDENKIRPLLYFKREQIEAYIKRNNIPYVQDETNFNLKYSRNYIRHRIVPALKLLNSDLENAFSQVHFSGMMLENHVKRLIKKYSERIFRCGKRIIFDSKDMDEFEIIELVKYCAGQMNVDLNYRQIQLVVSKLNENSWSIDLSEDIAIKKGFDFFSIEKKCKFMNILKVGKPGVYKFNDWTFELSSEVKSNEYVFIHDQGGVCIRKRKAGEKIAGVKMKDMMIDSKIPAFLRDEMPVVCTIDRIIWVPYVYVDRCFKERKEDSLVLNLLQNPYSCILELRKDERRKMV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_SYNJA
Sequence: MPAWLLAVAEPVTEATEGSAEKGILDAILESNLINIAIILSLLYILGRRVVGEALAKRREGILEELRQAEQRKQEAIERLAEEQQKLAQAQQEAERIRKQAEANAEARRQELLQQAEREIERLRANAERDLSAEQEQILQELRRQIVRQALSKVEQELPQHLNEQVHQRLIERGIQMIAR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: BIOH_PECCP
Sequence: MATLYWQTEGAGNTDLVLLHGWGLNAQVWQSIIARLAPHFRLHVVDLPGYGRSQGFGAMSLSDMANIVLAQAPERAIWLGWSLGGLVASQIALSAPERVDKLITVASSPCFSAQDGWPGIKPDVLQGFQQQLSEDFQRTVERFLALQTLGTESARQDARLLKSVVLEQPMPSVEVLNGGLDILREADLRQPLADLAVPFLRLYGALDGLVPRKVAGLLDEQWLNSTSVVIPKAAHAPFISHPDAFTEQVIAFAQA
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCNA6_TITDI
Sequence: MKGMIMLISCLMLIEVVVGGKEGYLLDRSNGCKRSCFFGSTSWCNTECKSKSADKGYCAWPSCYCYGFTDDSKMWHLKTNKC
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  Is toxic to arthropods (By similarity).
What are the official names of this protein?
Toxin TdNa6, PT-Arthr*-beta* NaTx1.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.