PharMolix/UniProtQA huggingface dataset:
Protein: SYT_ECOLI
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
ThrS is also a translational repressor protein, it controls binds its own mRNA in the operator region upstream of the start codon (PubMed:3086882).  The mRNA region upstream of the start codon has a tRNA-like secondary structure; mRNA and tRNA compete for binding to ThrRS (PubMed:2254931).  ThrRS represses translation by preventing the ribosome from to mRNA, and tRNA(Thr) acts as an antirepressor allowing fine level control of enzyme synthesis (PubMed:2254931).  X-ray structures prove that operator mRNA and tRNA bind to overlapping sites in the protein (PubMed:10319817, PubMed:11953757).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SREA_AJECA
Sequence: MTGLLASRLRAEGARSPTKGTDIPMRQPSAEDLDAAHQLVSSARGGRDNVMNFRSDRQEMTGKALDNTQGDGSRNMDSQLQNGHKAPVEQRAGESPPESGANPIDHPTSSKKSPKAQSKEQAFTGHSCSNCGTKRTPLWRRSPTGATICNACGLYLKARNTDRPTHRSRSLLTPYGSSSAQTLDKSRSSTSPTNDGNDPRLTDTWSNYAVKECTPSGSCPGGGSCNGTGGAEGCDGCPAYNNRVYKSAARNAMALHTPRTSPQVSTQGGPGSTEGDAGSSNPETMTLHIACQNCQTTVTPLWRRDENGHPICNACGLYHKLHGAYRPPTMKKSIIKRRKRVVPAMREQSPPSATQSSNGSVSPEASPAALAHNHDSHRQYQNVEHGNGHPPPHTRPLYSHAYHAPPPADFTGYTSNVISLPHHPPSTSQQLRPYDNNHNNGETTNTHRAPMPALHNPKKRTISESSIEDSQRPQASQILTHIPQINPPTPPSSSSASFPNNNPGRFNSISSLLNHPGEAATVTAHDRDDSRVDPALSSAVAPRTQQPQQEHQHASAGSHSPPRFSPSLSPAPPSTTAVPVGGGSGSGAAAVAGVVDHRDAKAERRARLQREAQDMREALKAKERELALLE
What is the function of this protein?
GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence element 5'-(G/A)ATC(T/A)GATAA-3' of target promoters in an iron- and zinc-dependent manner (PubMed:18549241, PubMed:22117028).  Regulation occurs via direct binding of iron ions (PubMed:18549241).  Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity) (PubMed:22117028).  SRE1 targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis, presumed ferric reductase activity, iron-responsive transcriptional regulation, oxidative stress response, as well as genes encoding a number of putative oxidoreductases, metabolic and mitochondrial enzymes, superoxide dismutase, and genes previously identified as induced during nitrosative stress (PubMed:22117028).
What are the official names of this protein?
GATA-type transcription factor SRE1, Siderophore uptake regulator SRE1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRAC1_HUMAN
Sequence: MSLAAYCVICCRRIGTSTSPPKSGTHWRDIRNIIKFTGSLILGGSLFLTYEVLALKKAVTLDTQVVEREKMKSYIYVHTVSLDKGENHGIAWQARKELHKAVRKVLATSAKILRNPFADPFSTVDIEDHECAVWLLLRKSKSDDKTTRLEAVREMSETHHWHDYQYRIIAQACDPKTLIGLARSEESDLRFFLLPPPLPSLKEDSSTEEELRQLLASLPQTELDECIQYFTSLALSESSQSLAAQKGGLWCFGGNGLPYAESFGEVPSATVEMFCLEAIVKHSEISTHCDKIEANGGLQLLQRLYRLHKDCPKVQRNIMRVIGNMALNEHLHSSIVRSGWVSIMAEAMKSPHIMESSHAARILANLDRETVQEKYQDGVYVLHPQYRTSQPIKADVLFIHGLMGAAFKTWRQQDSEQAVIEKPMEDEDRYTTCWPKTWLAKDCPALRIISVEYDTSLSDWRARCPMERKSIAFRSNELLRKLRAAGVGDRPVVWISHSMGGLLVKKMLLEASTKPEMSTVINNTRGIIFYSVPHHGSRLAEYSVNIRYLLFPSLEVKELSKDSPALKTLQDDFLEFAKDKNFQVLNFVETLPTYIGSMIKLHVVPVESADLGIGDLIPVDVNHLNICKPKKKDAFLYQRTLQFIREALAKDLEN
What is the function of this protein?
Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking.  May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1.  May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway.
What are the official names of this protein?
Protein SERAC1, Serine active site-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SERAC1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Endoplasmic reticulum. Mitochondrion. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface.
Protein: GCH1_CAMJR
Sequence: MQKKFEDCVKTILEIIGENPNREGLIKTPNRVFKAYEFLASGYTQNVKDILNDALFESSNNEMVLVRDIEFYSLCEHHLLPFFGRAHVAYIPNKKVVGLSKIPRLVEVFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHMCVEMRGIQKANSTTTTSALRGIFLKNEKTREEFFSLINSAKQVRF
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: SECE_THEKO
Sequence: MAEFTEKVKSFLAESKRVLLVTKKPGMKEFKLAAKITGIGMILIGTIGMIIRIIGYLVTGS
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COXX_GEOTN
Sequence: MADLKAVQEADVRQRPQASIKLFWKELSAVVKIGIVNSNLITTFAGMWLAFYFTGERFLENLHIVFFTLFGAALVIAGSCSINNFIDRDIDQHMERTKTRPTVTGTMEPRRVLWLGVTLVAIGTMSLLMTTVTAAIVGLIGVVTYVFLYTLWTKRNYTLNTVVGSISGAVPPVIGWTAVDSDFHIVPLILFLIMFLWQPPHFLALAMKRCEEYRAAGIPMLPVVHGFEMTKRQIIVWVACLLPLPFYLFSLGIPFLIVATVLNVGWLLLGLWGLKMKDDIKWAKLMFVYSLNYLTILFVAMVIATIW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATC_AKKM8
Sequence: MLLRMALCLTVSTILCAGFASNLMDILRRPVNQVWDMFEESHLPAGIGLDAWSKAKEMATAMTSLGASQRALFLRQVSPSQADLTEAALVLRGAQPLPEDRKQVFIREGSPSTAVRDLAEALYSKGAVLADGTGRGALKMMSAFQPGEAFMLTIKLSLYAGVVISFPLLLYFLLQFIIPGLLEHERKLLYKCMAVGFGLFLAGTLFCYFIVLPRVLTFFYTYSLEFGISNEWRIGYYLSFATQMILMFGLAFELPVVVMPFVKLGVLTYDMMKSTRRYAIVAIAVLAAVITPTPDVATMMLMAVPMYALYEICIILAWMHERKEAARTREEIARFEEDFNNNNSPYNQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_PSYCK
Sequence: MTMFNTIKREFQYGNQQVVIETGRIARQANSILVHMGGVTVLVAAVVKSDAKEGQNFFPLTVNYQEKMYAAGKIPGAYGKREGRASESETLTSRLIDRPIRPLFPEGYVNEIQITATVVSSDKTQSADIAALIGASAALAISDAPFNGPVAAARVGFINGEYVLNPTLEELKESDLDLVVAGTKSAVLMVESEAAELSEDQMLGAVLYGHQQQQIVIDNIASMAAEIGTAKQQYTAPVRNQTLETGMKEQFGTQVSDAYTITDKQARYSKLDEIKDAALAALAGDAESESYADTVSELKEIYNDLKYRTVRDNILSGKPRIDGRDLETVRALDVQVGVLPFTHGSALFTRGETQALVTTTLGNTRDVNMIDSLAGTIRDHFMLHYNFPHFSVGETGREGIPKRREIGHGRLARRGVQAMLPDSDRFPYVIRVVSEITESNGSSSMASVCGASLALMDAGVPIKAPVAGIAMGLVKEGERFAVLSDILGDEDHLGDMDFKVAGSKDGITALQMDIKIEGITPDIMEQALKQAHAGRIHILDAMNKVLPESRTEINAHAPNYAVIEINPDKIRDVIGKGGATIRQLTEETGAVIDIDDAGTIRIFGENKAATKAAIAKIEAITAEVEVGKTYEGTVARIVDFGAFINVLPNTDGLVHISQIADERVENVSDYLKEGQIVKVLVQDVDNRGRIKLTMKGIEQS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_ROSCS
Sequence: MYVTHLSLRDFRNYERLDLNLEPGVTLLYGPNAAGKTTVLEAIYFLATTRSPRAGADRELVRFEAQGDLGVPPFARLVCDVVRADGYVRLEVVVQRRAEEESAIGATPTIKTVRIDRKAVRALDLVGNLRVVLFTPADIALVTGAPAERRRYLDVTLSQIDGRYVRTLAHYQKVVQQRNSLLRAWREGRRPLRYADDELAFWDRELAMAGAYLLRERLHAVVDLNALAGPLYCRMSGGDTPLTLAYQSSVAGIDSVTDSRAIEQAFLAHLTRLRDDEIGRGQTLIGPHRDDLLIAVGGVPIGAYGSRGQQRSATLSLKLGEAKLMRIRTGDAPVLLLDDLLSELDAERRSHVQDILERPDQQTIVTATGTDDFDLKFLTRARRWRVESGHLYPA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST1_CAEBR
Sequence: MRVLLASLLIFGACWAGPVVNTNYGKVEGFEYGAAEVFLAIPFAKPPVDNLRFEKPEAPEPWEDVYQATQFRNDCTPHYRLVAQFSSYSGEDCLTLNVIKPKTIEKKLPVLFWVHGGGYEIGSGSQHGYEFFADRYTSQGVIVVTIQYRLGFMGFFSEGTSDAPGNYGLFDQAAALRFVKENIGNFGGDPDDITIWGYSAGAASVSQLTMSPYTHDLYSKAIIMSASSFVGWATGPNVIDTSKQLAEILGCPWPGAKECMKKKTLHEIFDAVETQGWTTGTIDILRWSPVIDGDYLPKNPENLINDAPIKPTLIGMSNKEGSYFATMNMGRVIADFGLSPEEIPKVDEDFISEIIDRKLLYNNRYGENRQKVWDQILDYYTKQGKPERDLNGFYVDRYAELLSDITFNVPILREITARVERKTPVWTYRFDHYNEQIWKKYIPEQAKGSPHANEYHYLFNMPVMAQIDFKKEPESWLQRDLIDMVVSFAKTGVPHIQDVEWRPVSDPDDVNFLNFQSSGVSVKHGLFQEPLDFWNNLREREGFDLVDPAYSKTTSNSEKDEL
What are the official names of this protein?
Gut esterase 1, Non-specific carboxylesterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: YA965_ERYLH
Sequence: MAQHRISHISLDENTILWRNADIEQERRVAIYDLIEENTFKPVRSNAAGHTGPYRLHLSVQDGRLAMDIRDRDDEELEMLILGLARFRRPIREYFAICDSYYQAIRKATPSEIETIDMARRGVHNHAAELLIERLEGKVETDFPTARRLFTLICVLHIKG
What are the official names of this protein?
UPF0262 protein ELI_10965.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: SUCC_BURPS
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SECA_CHLT3
Sequence: MLKFIEKIFGSKHDRDIKRLWPIVDEINEHFESYKSLSDEALRGKTQELKEQIKEHISDIEQSIITEKKQLENLELTIEEAESIQEKIEGIEKELHDATEEALNEVLPEAFAIVKETARRLVGKEYPVMGSTNIWNMVPYDVQLIGGIVLHQGKISEMATGEGKTLVAVLPTFLNALTGKGVHIVTVNDYLAQRDKEWMTPIFEFHGLTVGAILGNMPPYQRKEQYACDITYGTNNEFGFDYLRDNMAGDPEDVVQREFNYAIIDEVDSVLIDEARTPLIISGPVPNADVNKYNEIKPRVERLVRAQQNLVAKILTETEKAIKTPNKADKDAEFNIGLGLLRAKRGQPKNNKFIKLIGEPNAARFMQTVENEFLKDNARRMHEVDEELYFSIDEKNHTIELTEKGREFMTDTHEDPDFFVLPDVGTEISKIDSDATLSEQDKVQKKDELYRLFSVRSERIHNVSQLLRAFSLYTRDDEYVVQDGKVLIVDEFTGRILPGRRYSDGLHQALEAKEGVKIEGETQTMATITLQNFFRLYKKLAGMTGTAETEASEFFEIYKLDVVVIPTNKPIVRKDQEDLIFKTKREKYNAVINKIQELQEKGQPVLVGTTSVDVSETLSRMLKMKHIEHNVLNAKQHAREADVVANAGHKRAVTIATNMAGRGTDIKLGEGITEVGGLFILGTERHESRRIDRQLRGRAGRQGDPGTSVFYVSLEDDLMRLFGSDRVISVMDKLGHQEGDVIEHSMVTKSIERAQRRVEEQNFAIRKRLLEYDNVMNQQREVIYTRRRKALEKRRLRIEIFDLLRDYADKHAEKFYQALDKDGLEEQVLRELSVDIKLTVDAFEKLGEDGIADKIYNTAVDFYKRKEELLGNDIMAQIEKYSVLGVIDQKWREHLRDIDDLKEGINLRAYGQKDPLLEYKQEAFKLFVDLLEEISTETLSFAFKLFPQQAAERATFIPERSRVRQERLVAQHEVAQSAYATAAPAAETTTTAKAADAARQQPPAAENEEQKRQPVHVEKTPGRNDPCPCGSGKKYKHCHGRNA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ATPK_PICAN
Sequence: LTTLIPPKVASASNLGSNPAAKRMQHIVSFYSKLPRGEASFPKAKSPLGLYREKYFDTGSGAPLLHASLFFLAVGYGLEYYFHLSHHKEH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(0) domain (PubMed:27791192).  Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27791192).
What are the official names of this protein?
ATP synthase subunit f, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase F chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: SYS_RICPU
Sequence: MLNIKWIRENKELFDEKLSQRFIEPMSSKIAMLDREKRKITSLIQEFQHARKVKSKILGNMASKSGEEFEGLQRDVKHINEKLEALEHDLNNNNELNELLNMFPNIPDEEVPYGMDESMNKLVRTYGETNPNALNKQHFELGIKLNLMDFEQTAKISGTRFVTLKGDLAKLERALINFMIDVHTKEWDFFEISPPVLVRDNAMYNAGQLPKFAEESFATTNGYRLIPTAEVSLVNMVADTIIPREKLPIRYVAYTPCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESTNEHEYITNASETILQKLNLPYRVMLLCTGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNEDGSITIPDVLINYMGGLQKIIAYSE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_METAC
Sequence: MSYLIIVRHGESGWNVDGRFGGWVDVPLTGKGIKEALLCAAELEGIDLDVTFTSKLIRAQETLFLILSKQKKIGVFVHEEAGTGEDRTEREDGSRKDRKEKRYAYPPNTEKNLIPIHSNEALNERYYGILQGKKKDKMKAKYGEEQILHWCRSFDEGPPEGESLKDIYRRAVPYFEKEIFPILQDGKNVIVCAHQNSLRALIKHIEGISNEDIRKIRLANARPVIYTFSGGRLVRENAETDPSVKRNL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RL16_POLSJ
Sequence: MLQPARRKYRKEQKGRNTGVATRGNSVAFGDFGLKCTDRGRLTARQIEAARRAISRHVKRGGRIWIRVFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKIVFEIVGVPEELAREAFRLASAKLPLRTTFVSRMIGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: C90D2_BRADI
Sequence: MEALSMVGSGGVYSWPAALLVAAIVVSASVRWWGIKRQPTTTESKARLPRGSLGWPVVGETLAFISAAYSAQPESFVDKRRLLYGKVFKSHLWGSKAVVSSDAEVSRAVLQADASAFVPWYPSSLMQLMGESSILVLGGGLQRRVHGLAGAFFKSPQLKARLTVDMQRRVADAMDAWQCHGVVRVQDEAKSIVFEILVKALIGLEPGQEMHYLKQQFREFIAGLISLPIKLPGTQLYRSIQAKKRMAKLIQKIVQEKREKRMGGNNNATCKAPRDMIDVLMSNGSEELTDELISDNMIDFMIPAEDSVPVLITLAVKYLSECPLALEQLEEENMELKKRKSAVGGTLEWTDYMSLAFTQHVITETLRIGNIINGIMRKAVKDVEVKGQLLIPQGWCVFLYFRSVHLDGHIYDDPYAFNPWRWKERDMMAASSGFTPFGGGQRLCPGVDLARLEASIFLHHLVTTFRWEAEDDTVVTFPTVRLKRGMPIRVSQNIETSGTATFRSTESASV
What is the function of this protein?
Involved in reduction steps of the biosynthesis of plant campesterol-derivative steroids, ending to castasterone (CS) but missing brassinolide (BL) (PubMed:32146811).  Catalyzes the conversion of (22S,24R)-22-hydroxy-5alpha-ergostan-3-one (22-hydroxy-campesta-3-one, 22-OH-3-one) to 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo-3-DHT), 3-epi-6-deoxocathasterone (3-epi-6-deoxoCT) to 6-deoxotyphasterol (6-deoxoTY) and of 6-deoxocathasterone (6-deoxoCT) to 6-deoxoteasterone (6-deoxoTE) (PubMed:32146811).
What are the official names of this protein?
Cytochrome P450 90D2, BdCYP90D2, 3-dehydro-6-deoxoteasterone synthase, 6-deoxotyphasterol synthase, 6-deoxoteasterone synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IXTPA_THISH
Sequence: MKIVLATGNAGKVRELSELLAGTGITILPQSDFGVPEAEENGLSFVENAILKARNAAAHTGLPAIADDSGIEVDALNGSPGIYSARYAGPGGDAEANNRKLLKALEHVESSQRTARFRCVMVYLRHADDPSPVIAEGSWEGRIASEARGPGGHGYDPIFEIPELELTAAEISPAEKNRRSHRGQALRILLERLQGR
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ARGB_BURA4
Sequence: MSEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDQALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVTLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_SHISS
Sequence: MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ATP8_SQUAC
Sequence: MPQLNPHPWFAILVFSWIFFLVILPKKVMTHLFNNNPTAKSAEKPKPEPWNWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: TDA2_YEAS2
Sequence: MSMQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNNNECYLITILWLHK
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: POTA_ECOLI
Sequence: MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.