PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_PYRNV
Sequence: MKIRVATRGSKLSLIQTEELLAQIKAVEPDIRFEIVVVKTTGDLIQDKPLFQIGVKGVFEKEVNLAVLRGEADMAVHSLKDLPSDLTPGLALAGYSRRAPPNDALVSPRGYTLETLPRGAVVGTSSVRRAEFLKAARPDLEIKPLRGNVDTRVAKILSGQYDAAVMAAAGLQRLYGGAPPIPAVPLAVEDLPPPPGQGIVAAVAREEDTWLTDLLRRASDRKAAAEAAAERAFLAEVGAGCHVAVGGIARQTPAGIEFTAGYAQGGRKHLVKVYGEDPTEVGRRAARLVAQAMKKT
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RK22_NASOF
Sequence: MIKNRKKKSYTSVYALGQYISMSAHKARRVIDQIRGRSYEEALMILELMPYRGCYPIFKLVYSAAANASHNKGFKETNLVISKAEVNQGNTVKKLKPRARGRSYPIKRSTCHITIVLEDISFYQQYEEYLMYLKKPGCSNENRNLTCHDTYSSGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YB61_SCHPO
Sequence: MYNVTYRLLRLSLISSHSLRKSRSFDVKNFANIHFFIPLPNTPKKFYSVNAFSPLLKARRMTATIVSNHNVGCSCCYFRQYSTKQFRDLNTSEALSPCKAEPIPYKIMSSMSNFSDFKSRFSQYRESHLKLLNELQNVKDTNDLKDRIRLLHLNSSSKLNAFLHDLINAPNVSAEMKENCVRLIFFGRKYDPFLRSRMFTLTIRYFLLQKNRLRTSFYLLKHMELLALPASYELKTTLLEWFLRKRKFETAQKIFLSLCFSQHFPSEKLLMVLLLHGTETMQEYAMIQAINFVNTEQKLRFYDRLHSICSKLKFSSTG
What are the official names of this protein?
Uncharacterized protein C12C2.01c.
Protein: IF1_COXBU
Sequence: MAKEESIEMQGTVVDSLPNTTFRVKLENGHVVTAHISGRMRKHYIRILTGDAVTVELTPYDLTRGRIVYREAGKKPPTSKAEE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ALIF1
Sequence: MSKQDEVIVVGKFGASYGIRGWLKVVSFTDQPESIFDYKPWLIQVKGEWVEFSVESWKRHKGLVCKLKGLDVREEAQTYTNLEIAVKADALPELSEDEFYWRELFGMEVVTTKGYALGVVDDIFETGSNDVLVVKANLKDAFGKKERLIPFIDEQVIKLIDREAQRIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_SYNS3
Sequence: MTSTLPTANTPDPASLMPSVRPEAHGRYGRYGGQYVPETLMPALAELEQAAAEAWKDSAFTTELNRLLKSYVGRATPLYEAERLSAHYRRSDGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVVYMGAEDMRRQALNVFRMRLLGATVQAVTAGTATLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMLVRDFHAVIGNEAREQCKESFGRLPDVLLACVGGGSNAMGLFHPFVQDTSVRLIGVEAAGDGVATGRHAATITEGRVGVLHGAMSLLLQDQDGQVQEAHSISAGLDYPGVGPEHSYLRDIGRAEYGAVTDDEAITALRLVSELEGIIPALETAHAFAWLEMLCPTLPNGSEIVINCSGRGDKDVNTVAEKLGNQL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y4136_KLEP7
Sequence: MLKTVHQKLLHHTRPLLAWLKLLWRRIDEDHMTTLAGNLAYVSLLSLVPLIAVVFALFAAFPMFSEVSVQIRHFIFANFIPATGDVIQGYIEQFVANSSRMTAVGAFGLIVTSLLLMYSIDSALNTIWRSTRSRPKVYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLDGVIDNLLRLFPLILSWAAFWLLYSIVPTTQVRNRDAVIGALVAALLFEAGKKAFALYITTFPSYQLIYGVISVVPILFVWVYWTWCIVLLGAEITVTLGEYRKLKTEETEQP
What are the official names of this protein?
UPF0761 membrane protein KPN78578_41360.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OMPX_ENTCL
Sequence: MKKIACLSALAAVLAVSAGTAVAATSTVTGGYAQSDMQGVMNKTNGFNLKYRYEQDNNPLGVIGSFTYTEKDRTENGSYNKGQYYGITAGPAYRLNDWASIYGVVGVGYGKFQQTENQGLNRTASNSDYGFSYGAGMQFNPIENVALDFSYEQSRIRNVDVGTWIAGVGYRF
What are the official names of this protein?
Outer membrane protein X.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CISY_RICPA
Sequence: DSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: RF2_ESCF3
Sequence: MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y024_BACC0
Sequence: MMRGGMGNMNNMMKQMQKMQKEMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKVKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCAH820_0024.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HOP2_DICDI
Sequence: MSKKITKKDEVEENILNLINKANRPYNYQMIEAAFPSMGKTQIVKTLKSLGEQGKLTFKEYNKAIIYWRIQDTGPKLDEQGYEIPQESIHDLNRKLDGINRQLEVEQDTLKSLISQSKQLNNQLSDEQIQKEVNQLSTENKELESKLLTFQTKEIMSDKDKQRLDDTIKKARSEWVKRKALFRDILDQVLERSNKKKKDLQEDIGWETDEDLKIQMIPDYSKPLSQQTLSSTNDESPFKKQKK
What is the function of this protein?
Required for proper homologous pairing and efficient cross-over and intragenic recombination during meiosis.
What are the official names of this protein?
Homologous-pairing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the HOP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CA216_XENTR
Sequence: MFTIQKPDTVSHLSHFHESKSLGSLPFPSDKERKQDTNFNILEETYDKNENWSQDKKGGEEGENKSKSEDEHSSLDNNRSQLKNRPIGQLKSTGSEGISLSSSEEEVRSPPEGAEIMQLEGDTPANDTANGFEKWAGSPLEDNGYASSSLSIDSPDSVSASTWQETTLPAPTTTPQENPETEDSDVESSSDSDSISVTLSEAFQSLQDKEKLKEREKEKHHAQLTMYRRLALLRWIRALQQKVRDQQNRLQESFDTILDNRKEMLRHMQHGYNKTPTKEAV
What are the official names of this protein?
UPF0500 protein C1orf216 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0500 family.
Protein: HEMW_MYCTU
Sequence: MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG
What is the function of this protein?
Probably acts as a heme chaperone, transferring heme to an unknown acceptor.  Binds one molecule of heme per monomer, possibly covalently (By similarity).  Binds 1 [4Fe-4S] cluster.  The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity).
What are the official names of this protein?
Heme chaperone HemW, Oxygen-independent coproporphyrinogen-III oxidase-like protein Rv2388c.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_HAEIN
Sequence: MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESLNLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRGVRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPSMVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRALLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMRDKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQTD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS2_ARCFU
Sequence: MARTGFQGRKLGEAFEIWTEMLREENITILMGLSGAMVPAGMRKIIAWLIRNRYIDVLVSTGANLFHDIHEAMGFRHFMGSEHVNDCKLFEEGIDRIHDVFAYEKEFNVIDYTLAEIISEMSGVMSSREFLEEIAGRLNVKDRNSIVIAAYESKVPIFSPAIADSSIGIAAALAKREVVIDTIRDVEELTEIVVNSEKTGVIYVGGGVPKNFIQQTEVVARLKGYDVRGHEYAIQITTDVPQFGGLSGCTFEEGVSWGKISGKAKKVQVNCDATIALPVLAHGLIGIRRQKYPIFNGL
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase 2, DHS 2.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: TAL_RHIEC
Sequence: MTSKLDQLREITTVVADTGDIEAVARLKPVDCTTNPSIVLKALGTPMFADAIKEAVAWGKKQGGNPDAVSSAVADRLAISVGAALVKLVPGRVSTEVDADLSFDTEASLAKARSIIAAYKDRGIDRDRILIKLASTWEGIRAAEVLQKEGIDCNLTLLFSKAQAIACADAKVFLISPFVGRILDWYKKSTGKDYTAEEDPGVISVREIYNYYKANDIKTIVMGASFRNAGEIEALAGCDRLTISPALLDELSKDDGKLERKLSPESRKPDAKVSVDEKTFRWMMNEDAMATEKLAEGIRAFAKDLTTLRTMVQKELQLAAA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_LIMRD
Sequence: MAKEKQEEQQKQTAPENEKAPKKDIKKEASDKKGDQTSKLKEEIADLKKQLADKDDKYLRAEAEIQNMTNRFNKERAQILKYDGQDLAKSILPVLDNLKRALAIEVVDDNGKQLKKGIQMVHDHLVKALNDHGITEIKADGETFDPTLHQAVQTVPVEEGQKPETVVNVLQAGYQLKDRVLRPAMVVVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL118_PLAVT
Sequence: MRGAYYVTIALLVVASSQISAEFGHQLQAYDHDVTAADDAVAETLAKRSLRGSRDVSNDVAIEERTKYSNVIEDGIEMLLRAAEALKEMPRAAVAVKDMPRAEEAVEKMAPIAEQDLLKNVIGADEASKRRRAPHGISTQRTLALPFKEWNTELKQMRGGSVLKKYRSKIKSVHQAFVDLCDKDLNPTVTETALLWGMFDWDVKSYSASAHKHNLIRLAKRYVHKDVVQIQSDDLAWNRWNEVSIPLRIGALNILLNLHYQRWVRMYNIFEQYQSALIGTPVSLELSLGGTTGTSSATALDKHLEVPMNKASTSKGKSSVFTRSSKRAFDSKTGTTSPSSKHSKMQRSSSPLTESTTSGDDPVFTKRSRHGVAVTSLSSISN
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 118.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: DDL_CORGL
Sequence: MSNSNSGKVRVAVVYGGRSSEHSVSCVSAGAIMAHLDPEKYDVIPVGITVDGAWVVGETDPQKLTLIDRTMPEVEHHEEVRPSLDPAHRGEFHFSDGSLYATADVIFPVLHGRFGEDGTVQGLFALSDIPVVGPGVLASAAGMDKEYTKKLMAAEGLPVGREVILRDRTELTEAEKNLLGLPVFVKPARGGSSIGISRVTAWEDFNKAVGLARAHDEKVIVESEIVGSEVECGVLQYPDGRIVASVPALLSGTESGAGGFYDFDTKYLDNVVTAEIPAPLDEKTTELIQSLAVESFQALACEGLARVDFFVTANGPVLNEINTMPGFTPISMYPQMFTASGVAYEELLDVLVQQALHRDN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_LEGPA
Sequence: MEENKQKALSAALSQIERQFGKGSVMRMGDSTVSRDIEAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLQVIAECQKMGGTAAFIDAEHALDPSYAQKLGVKVDELLVSQPDTGEQALEITDMLVRSAAVDVVIIDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTANIKRSNTLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKKGEEILGSETRVKVVKNKVAPPFKMTEFDILYNEGISRESEIINLGVQLNLIEKSGAWYSYKQEKIGQGKENVRLYLKENPQVAAELEQQIRTELLEKKLSVLASSSEDLFETIDD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_ECOLI
Sequence: MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD4_RAT
Sequence: MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDWRALMKRKRMKANMKLVGSGFPLPTSDLDDSLTEDIDEKIAFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRPTYDEPHLLMNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDLEHERLQLEKERLQIEREKWRLQLVSTEKPALENELGQGEKSMLQPQDIEAEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKERLRIQKEGHLP
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 4.
Protein: FABV_BURP6
Sequence: MIIKPRVRGFICVTTHPAGCAASVREQIAYVARRGPIERGPKKVLVIGASTGYGLAARIAAAFGAGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAARGLQATSINGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPRRTHPKTGVTHQSTLKPIGHAVRLRGIDTDNEAIKETLLQPATPDEIADTVAVMGGEDWRMWIDALDAAGVLADGAKTTAFTYLGEQVTHDIYWNGSIGEAKKDLDRTVLALRGKLAARGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKARGTHEGCIEQVDGLLRDSLYGAQPHVDAEGRLRADRLELDPAVQTRVLELWDQVTDDNLYTLTDFAGYKAEFLRLFGFGIDGVDYDAPVEPNVRIPNLIE
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: IQCN_MOUSE
Sequence: MAAMQPAAQLQFQNLMSPSGPSLPQPTPIHQEKVAKLCPQLQHDFYPSEELAVLPSQEVPRLRAVVESQAFRNILVDEMDMMVSRAATVIQASWKGYRLRQKLISQMTAAKAIQEAWRRFSTRRLMHSNRLTVKKAKREDEEDIPYHQPQQVRFHAPEDQPPVMVTKETQFPSFDNLVPSQATAGPCASRVPGGGLHPQYVINRLTVPKYQPCMLTKTFRSSCLMRHLEGDSLKIRHVASKTIKVGALEAAATGRYGQAMHGSLKTQTQAHTESDVPKAPLRIYPVNKTHTKVCPMAAAVPESSATMSTAPRSAPQARPTSPATVMKMQATTSPTSPVIRLPAPVGPNSSLSNTTPQMQVRYMMPGARIQPPGSAVASTIKALPHFGAPVMKVPLQTGPGFTMTKTSLQMRPMTRSQAQTYTVSTSSKTSPSSPTVKPSPQTRLAAMLTKTPAQLRSVAAVFRTLCGGTTEAVASSPRCSPQSPVVAGNTPSQVHLNSTRTKVTVSTKQATTVVKVNSQSYLGRCGSQGNLDTIVPKPPATYPLEVEKMKSCPARSPKKEAALKTNTTIAARALSWTKMMEDRSKALTQIKQRAEIIKVHFRVYMPEEIPVTLTQAQLAVPLTKSSSQIQPPPCHARTQPTSPFCKAVSQSCMPSGLAHGTPEGQRPPVGLSASLSSSPLAAHLMSLTAQLQPACEQARSVSRDHLTRSCPASASLQARSSGTIVPPEVYPNTYSPTSAPQHHMASLLAKSSSQLHPPAEHAKTMNTKTTKAACQVCPSTKLSKAPSLAQLITCLAKVPSQAQLATETAKCLLAAHPTTDHRSKTQSQTFLSSSKASVQLWQHLGTLSTGSRAKPDDRSVAQPQLHSHAPNKTMQNPRSVVTDSQGMLIPLMTPSGHPVCNAESWGDSGRAQTPPPSPVPNQAVPCHDDLAASVASLCADLVAMLGSPEDLRTLLVKTLSQGEVRTALSQALSREVLGPSVVKALPQGMLGMALMKALSWGELGISLSRALSRGELRPELNKATQGKLAEVLCKALTEEERATLSQALCQGELGAVFTQSLAQMAQRTGTFLPKATSKTVGSRMTTAPAPVEVTCSGSLSVAWGPAMGPVGARCSKGPVDAGLASGQSWNSKVPNVSVRATAHAGAPQGVWYPSRGHKPWDPIGAEAELDRKPSAELLMSVQGMEKVVVQAVVTIQACARGYLVRRTVKVWHQWATIIQATWRGYRVRRNLERLFRATTIIQAAWRGYCIRRARARQVLLPIAWPEHSGRTKGTLDNRNSSEHRCFLSCQPDVCSVCQSLGPPVESPPSVVMLVGSQPRTCHVCGHTLSTRVVQGFGQGISGQPVSRWASASQQNTLLSQQHRACTIIQAAWKGYRTRRQLSQKQSAAKMVQAVWRGHYTRSCLTTDALLGTGGPWSISRDTSRHSSRAYSLHWPGV
What is the function of this protein?
Essential for spermiogenesis and fertilization.  May be required for manchette assembly in elongating spermatids.
What are the official names of this protein?
IQ domain-containing protein N.
Protein: RUVB_SHEB9
Sequence: MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDDTRAQLKVFIQAAKNRNEALDHMLIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIPLRLEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDGAVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIATVRAYQHFELIKPE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL34_STAAN
Sequence: MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TDIB_EMENI
Sequence: MATEYWSRHLRSVLAPLFAAAGTYSPEDQESHLAFIDEHIAPNLGPLPWEPHGPYSTPSSLVGSPFDPSINIVSSGKAKVRFDFDVISPPDRTGPDPFAEGSAREILHRLADLVGADTQWMGYLMDALYLTPAEAEVAKTKLPPGVAIPPSSVGFDFDGPERTLKFYIPSVRKALATGQDVSELMLKTLRGLQPLGSELVPAMDLIASYLSTRTNDAMLPLVGIDCLDPRTHKNARVKCYLHTSSNSFAVVRDVLTLGGRLSDDTSLKRVETLKSVWPLLINELEGPQSDAATMDESWSKPERLNRTGYSGIQYTIEITPGQAIPDTKIYVPLFQYTDSSEVAERNFESALKKLGNEWGLSGKYRSVMQEIFKDVENYGQTYASFSYTEGKGVYTTSYVAMPIKDEGGGSLAGDFGFRN
What is the function of this protein?
Indole prenyltransferase; part of the gene cluster that mediates the biosynthesis of terrequinone A, an antitumor agent (PubMed:17704773, PubMed:16426969, PubMed:17291795, PubMed:22083274).  The first step in the biosynthetic pathway for terrequinone A is formation of indole pyruvic acid (IPA) from L-tryptophan by the aminotransferase tdiD (PubMed:17704773).  The nonribosomal peptide synthase tdiA then immediately converts unstable IPA to didemethylasterriquinone D (DDAQ D), via condensation of 2 IPA molecules (PubMed:17704773).  The symmetric connectivity of the 2 IPA molecules is thought to arise by head-to-tail dual Claisen condensations facilitated by the TE domain (PubMed:17704773).  TdiB then catalyzes reverse prenylation by transferring dimethylallyl diphosphate to carbon atom 2' of DDAQ D, to yield asterriquinone C-1 (PubMed:18029206).  Finally, tdiC and tdiE enzymes robustly convert asterriquinone C-1 to terrequinone A via a transformation involving regular prenylation at carbon atom 5, which requires elimination of the hydroxy group on C-5 (PubMed:17704773, PubMed:18029206).
What are the official names of this protein?
Indole prenyltransferase tdiB, Terrequinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: GANA_ASPTU
Sequence: MIYPLLLSALPLLSSAALTYRGADISSLLIEEDAGISYKNLNGETQALEDILVNNGVNSIRQRVWVDPSDGSYDLDYNLKLAKRVQAAGMSIYLDLHLSDTWADPSDQTTPTGWSTTDIDTLTWQLYNYTLEVCNTFAENDIDVEIVSIGNEISSGLLWPLGKTSNYDNIAKLLHSGAWGVKDSDLTTTPKIMIHLDNGWDWDEQEYFYKTVLATGSLLSTDFDLMGVSYYPFYSSEATLSSLKTSLTNMQSNYDKPVVVVETNWPVSCPDPEYSFPSDLTSIPFSAAGQEEFLEKLAEVVEGVTDGLGIYYWEPAWIDNAGLGSSCADNLMVDVNTDEVLESVTVFEDL
What is the function of this protein?
Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.
What are the official names of this protein?
Probable arabinogalactan endo-beta-1,4-galactanase A, Endo-1,4-beta-galactanase A, Galactanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
What are the subcellular locations of this protein?
Secreted.