PharMolix/UniProtQA huggingface dataset:
Protein: STYK1_MOUSE
Sequence: MGEKGHLSRVLLECSLSDKLCVVREKQYEVIIVPALLVGGFLILLAIILWLFIRGQRSQRQSPGPRGTASVPASRGRSQEAAGHGEKVLLPLKETSVEGFLRAATPRLAKLQVPREQLLEVLEQIHSGSCGTLYHATMTTKDHPKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQILLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRLEAASRSADDKAVLQVPELVVPELYADVAGIRAESISYSFSVL
What is the function of this protein?
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice.  When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs.  May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.
What are the official names of this protein?
Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, mNOK, Serine/threonine/tyrosine kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CIGR2_ORYSJ
Sequence: MADTPTSRMIHPFSNIPSQNLKQFQYSDNPQHPCHPYRAPSDTHVVPHHYGLKSHSPDAGYESQATPNKYTLDSSEGAGCMRHDSPSSQSFTTRSGSPLSQEDSHSDSTDGSPVGASCVTEDPNDLKQKLKDLEAVMLGPDSEIVNSLENSVANQLSLEPEKWVRMMGIPRGNLKELLIACARAVEEKNSFAIDMMIPELRKIVSVSGEPLERLGAYMVEGLVARLASSGISIYKALKCKEPKSSDLLSYMHFLYEACPYFKFGYMSANGAIAEAVKGEDRIHIIDFHISQGAQWISLLQALAARPGGPPTVRITGIDDSVSAYARGGGLELVGRRLSHIASLCKVPFEFHPLAISGSKVEAAHLGVIPGEALAVNFTLELHHIPDESVSTANHRDRLLRMVKSLSPKVLTLVEMESNTNTAPFPQRFAETLDYYTAIFESIDLTLPRDDRERINMEQHCLAREIVNLIACEGEERAERYEPFGKWKARLTMAGFRPSPLSSLVNATIRTLLQSYSDNYKLAERDGALYLGWKSRPLVVSSAWH
What is the function of this protein?
May play a regulatory role in the early step of oligosaccharide elicitor response, downstream of the membrane-associated high-affinity chitin-binding protein.
What are the official names of this protein?
Chitin-inducible gibberellin-responsive protein 2.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: STAC3_XENTR
Sequence: MFKKKAKEEKPSPVPDAQQNGELPNSGPIIYYIYESEEEEEEEEEEPPPEPPRPVNDKPHKFKDHYLKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHHHCQSYVEFQKCFGKIPPGFRRAYSSPLYSNQQNACVKELMPFSASNRTDPVFDTLRVGVIMANKERKKGQDDKKNPMLEEEPEELPPKPEEKQEGDVPDGDKKGEKGGQDAKNKKAQPGFMQSHYFVALYRFKALEKDDLDFQAGERITVIDDSNEEWWRGKVGEKAGYFPANFIIRVRAAERVYKVTRSFVGNREIGQITLKKDQIVVQKGDEVNGYIKVSTGRKVGLFPLDFLQEI
What is the function of this protein?
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization.  Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction.  Probably functions via its effects on muscle calcium channels.  Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane.  Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane.
What are the official names of this protein?
SH3 and cysteine-rich domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma, T-tubule.
Protein: RL15_YERP3
Sequence: MRLNTLSPAEGAKHAPKRVGRGIGSGLGKTAGRGHKGQNSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAMITAEVRLSELALVEGDVIDLNTLKAANVVGIQMEFVKVILSGEVNRAVTLRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GOBP1_EPIPO
Sequence: MATVSKWRMLVLTLCLTGVWQVESSADVMKKLTTGFATALEKCRDELNLPDAVMQDFFNFWREDYELVNRDMGCAIMCMATKFDLVTEEQKLHHGNAHEFAKSHGADDSMAKQLVTMLHECETQTASISDDCGRTLEIAKCFRTKIHGLKWAPSMETILEEVMTEV
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 1, GOBP 1.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: CH10_BLOFL
Sequence: MKIRPLHDRVIVKRKEVESKSSGGIVLTGSAAGKSTRGEVLAVGHGRVLENGGIKALDVRVGDTIIFNDGYGVKVEKIDNEEVLIMSENDILAIVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1283_BURCH
Sequence: MTELMRIAALFAATALAEIVGCYLPWLVLKAGRPAWLLVPAALSLALFAWLLTLHPSAAGRTYAAYGGVYIAVALIWLRVVDGVALTRWDVAGAVLALGGMAVIALQPRA
What are the official names of this protein?
UPF0060 membrane protein Bcen2424_1283.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PD2_SCHPO
Sequence: MLSIIVFGASGDLATKMTFPALFALYVRKIIPEDFQIIGYARSKLSQEAANKIVTAHIPIDDTVGASQKALNTFVEHYKYVPGTYDKPESFEMLNSIIAEKETAPASECTRIFYLVLPPHLFAPVSELIKSKAHPNGMVTRLIVEKPIGFDYKSADAILSDLSKHWSAKDTFKVDHFLGEDMIDGFTAIRFANSMFEPIWNREHIESVRVDFREDFGCEGRGGYFEGAGILRDVVQNHLLQLLTLLCIEEPKSQDAEDIIKCKVDFLKSLHPVSKEDIVYGQYTKSANGKVPGYRELDGVADDSEVSTFCALQLRSEAPRWKGIPIIISAGKGLDRDYFEARITFKRREGGMFPTVDSSNVLVLRVYPKEFIALKGHIKQPGFSRQIVPVTLDVKYPEAFPDTWIHKAYEVVIADAINGKHTHFISDDEVRTSWKIFDDVLDTTGDLSPLPYAFGSHHGPDATLEFFKKRNLEWD
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase gcd1, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: GLGX_CITK8
Sequence: MTQLATGKATPHGATYDGHGVNFTLFSAHAERVELCVFDALGNEQRYDLPGRSGDVWHGYLADARPGLRYGYRVHGPWQPAQGHRFNPAKLLIDPCARRVEGELKDNPLLHGGYDEPDHRDNAAVALKCVVTADRYDWEDDAAPRTPWGNTVIYEAHVKGLTYLHPAIPSEIRGTWKALGHPVMIAYFKQLGITALELLPVAHFASEPRLQRLGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIKEDGDYHNWTGCGNTLNLSHPGVVEFACECLRYWVETCHVDGFRFDLASVMGRTPAFRQDAPLFTAINNCPVLSSVKLIAEPWDIGEGGYQVGNFPPPFAEWNDHFRDAARRFWLQRNLPLGEFAGRFAGSSDVFKRHDRLPNASVNLITAHDGFTLRDCVCFNQKHNEANGEENRDGTNNNYSDNHGKEGLGGTLDLIERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANSGLTTFTAALIHLRQQIPALVGNRWWEENDGNVRWLNKNAEPLSAGEWENGPKQMQILLSDRFLIAINATLEVTDIVLPEGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: FMC1_RAT
Sequence: MAALGSPARTLRGLLRELRYLNAATGRPYRDTAAYRYLVKAFRAHRVTSEKLCRAQHELHFQAATYLCLLRSIRQHVALHQEFHGKGERSVEESAGLVGLQLPHQPGGKGWEP
What is the function of this protein?
Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
What are the official names of this protein?
Protein FMC1 homolog, Formation of mitochondrial complex V assembly factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the FMC1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNFG_RHOCA
Sequence: MTDTPPPEKPKLPWFKASPLAHGIMLAMFALVTAVLLAVANDSTSAPIAARGAEDLAASLEQVIPHDLHDNDLAAAMRPVSDAEEGTIKVYVATKAGAVTGLAYELSGPGYSGQIRVLLGIAPDGTLLGVRVLSHTETPGLGDKIEVAKDDWILGFAGKSLADPEPGHWKVKRDGGVFDQFSGATITPRAVVKTIYRGLMFFDRNKAALTAPLPPKS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).  Required for nitrogen fixation.  Involved in electron transfer to nitrogenase (PubMed:8264535).
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Nitrogen fixation protein RnfG, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Single-pass membrane protein.
Protein: RSMA_CLOBM
Sequence: MNTKEIVNKYEFKFNKNLGQNFLVDESVLEDIIKGAEISKEDTVIEIGPGVGTLTKELLERAKEVYSIELDGDLIPILQEELKEYNNFTLIHKDALKIDFNGLMENKDSIKLVANLPYYVTTPIISRLLKEKCDFKSLTIMIQKEVAERIDAEPNCKEYGSLTVLVQYYCNTEIIRKVSPNCFIPRPKVDSIVIKLDRLSEPRVRVKSEKLFFNVVRSSFNMRRKTLWNSLKSLNIDKESMENAFERAGIDPKRRGETLSIEEFGKLSDCIYDIL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_BORBU
Sequence: MDRYFFLQDATTVAKLLLGNLLIRKIDKEEIVTRIVETEAYMGITDSACHSYGGKITNRTSAMYRIGGYSYVYIIYGMHYMFNVVTADKNNPQAVLIRSVEPISPLLGEKSILTNGPGKLTKFLNIDLTFNKVDLIGNNELFLQRGLNLDFNIVCSKRININYAQESDINKLWRFYIKDNKFVSRR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: Y1972_METMJ
Sequence: MVDDELAELRRRRMEQMQRQAMDQQGMEEEAARQQQIDAQVRAALMEILEPEARERLNTIKLTRPEFAKAVEQQLVMLAQSGRVRQRITDEQLKALLAQLTPSKKEFRITRK
What are the official names of this protein?
DNA-binding protein Memar_1972.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: Y493_HAEIN
Sequence: MRGRTRIGKFTTCGERNPKKVARTQPTKKDLKTQNPILHSDQGWLYQMVGYQAILRENSIQQNMSRKGNYLDNNAMENFFGRLKTECYYDKRFETFKQLKKQLMSIFIITTMITFRGN
What are the official names of this protein?
Uncharacterized transposase-like protein HI_0493.
What is the protein family that this protein belongs to?
Belongs to the transposase IS3/IS150/IS904 family.
Protein: THII_ECO8A
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEVNNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNRTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PARMW
Sequence: MHIAVVGLSHRTAPVEIRERLSIPEQTMETSLQSLRGHEQVLEASILSTCNRLEIYTLVRHPDLGVSAVSEFLSGHSGLATGELTPHLFNYHHEDAVDHLMRVAAGLDSLVLGEGQILSQVKKMMRLGQEHKSLGPILNRLLTQAVSTGKRVRSETNLGTGAVSISSAAVELAQLKLGQSRGLDQLVTLESEQIAVVGAGRMSRLLLQHLQAKGASGVVLLNRTVQRAELLAADFPDLPVQCRPLTDLDQCLSTCSLVFTSTAADDPIIDAARLEPLNRRSKLRLIDIGVPRNIAADAAAVDGVESHDVDDLQEVVARNQEARQAMAREAEQLLQQEAQQFLEWWDSLEAVPTINRLRSSMETIRVEELQKALSRMGPDFSARERKVVEALSKGIINKILHTPVTSLRAPQGRQERQQALRTVERLFSLGDD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GTR3_CHICK
Sequence: MADKKKITASLIYAVSVAAIGSLQFGYNTGVINAPEKIIQAFYNRTLSQRSGETISPELLTSLWSLSVAIFSVGGMIGSFSVSLFFNRFGRRNSMLLVNVLAFAGGALMALSKIAKAVEMLIIGRFIIGLFCGLCTGFVPMYISEVSPTSLRGAFGTLNQLGIVVGILVAQIFGLEGIMGTEALWPLLLGFTIVPAVLQCVALLFCPESPRFLLINKMEEEKAQTVLQKLRGTQDVSQDISEMKEESAKMSQEKKATVLELFRSPNYRQPIIISITLQLSQQLSGINAVFYYSTGIFERAGITQPVYATIGAGVVNTVFTVVSLFLVERAGRRTLHLVGLGGMAVCAAVMTIALALKEKWIRYISIVATFGFVALFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMLFPYAEKLCGPYVFLIFLVFLLIFFIFTYFKVPETKGRTFEDISRGFEEQVETSSPSSPPIEKNPMVEMNSIEPDKEVA
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, CEF-GT3, Glucose transporter type 3, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: E2F3_HUMAN
Sequence: MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
What is the function of this protein?
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication.  The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase.  E2F3 binds specifically to RB1 in a cell-cycle dependent manner.  Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).
What are the official names of this protein?
Transcription factor E2F3, E2F-3.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDI_BRUAB
Sequence: MSLIVYFSSRSGNTHRFVERLGVRSSRIPLEASGALQVREPFVLVTPTYGGGSTKGAVPNPVIRFLNDADNRALIRGVIAAGNSNFGEAFCIAGNIISAKCGVPYLYRFELLGTAEDVGNVRNGMEQFWTRQTQA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: ZN776_HUMAN
Sequence: MAAAALRPPAQGTVTFEDVAVNFSQEEWSLLSEAQRCLYHDVMLENLTLISSLGCWYGAKDETPSKQTLSIQQESPLRTHWTGVCTKKVHLWGMCGPLLGDILHQGTQHNQKLNGFGAYEKKLDDDANHHQDQKQHIGEKSYRSNAKGTSFVKNCKFHMSHEPFIFHEVGKDFLSSLRLLQQEDIHTSGKSNFETKHGIPLQGGKTHYICGESTIPFSNKHSLVLHQRLLPREGPYVCSDSGKFTSKSNSFNNHQGVRTGKRPYQCGQCDESFWYKAHLTEHQRVHTGERPYECGECDKSFSHKHSLVDHQRVHTGERPYECDECGKSFSHKRSLVHHQRVHTGERPYQCGECGKSFNHKCNLIQHQRVHTGERPFECTACGKLFRSNSHLKEHQRVHTGERPYECKECRKSFRYKSHLTEHQRVHTGERPYECRECGKCFHQKGSLIQHQQIHSGERPHECGECGKCFHQKGSLIRHQQIHSGERPHECGECGKCFRQKGNLIKHQRVHTGERHHEC
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 776.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KO1_ARATH
Sequence: MAFFSMISILLGFVISSFIFIFFFKKLLSFSRKNMSEVSTLPSVPVVPGFPVIGNLLQLKEKKPHKTFTRWSEIYGPIYSIKMGSSSLIVLNSTETAKEAMVTRFSSISTRKLSNALTVLTCDKSMVATSDYDDFHKLVKRCLLNGLLGANAQKRKRHYRDALIENVSSKLHAHARDHPQEPVNFRAIFEHELFGVALKQAFGKDVESIYVKELGVTLSKDEIFKVLVHDMMEGAIDVDWRDFFPYLKWIPNKSFEARIQQKHKRRLAVMNALIQDRLKQNGSESDDDCYLNFLMSEAKTLTKEQIAILVWETIIETADTTLVTTEWAIYELAKHPSVQDRLCKEIQNVCGGEKFKEEQLSQVPYLNGVFHETLRKYSPAPLVPIRYAHEDTQIGGYHVPAGSEIAINIYGCNMDKKRWERPEDWWPERFLDDGKYETSDLHKTMAFGAGKRVCAGALQASLMAGIAIGRLVQEFEWKLRDGEEENVDTYGLTSQKLYPLMAIINPRRS
What is the function of this protein?
Catalyzes three successive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid, a key step in gibberellins (GAs) biosynthesis.  GAs, which are involved many processes, including stem elongation, play a central role in plant development.
What are the official names of this protein?
Ent-kaurene oxidase, chloroplastic, AtKO1, Cytochrome P450 701A3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein.
Protein: Y1158_CITK8
Sequence: MTVTDLVLVLFIVALLAYAIYDQFIMPRRNGPTLLAVPLLRRGRVDSVIFVGLVAILIYNNVTSHGAQITTWLLCALALMGFYIFWVRAPRIIFKQKGFFFANVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVRNIDDLERIYKLLVSSQ
What are the official names of this protein?
UPF0266 membrane protein CKO_01158.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMG_THENN
Sequence: MDFLRDVLQEYGVRFEESQIEKTFRYLNELLNSPHNLTALRSLDSAVHKNVAEILIPLKHENLRGSLLDVGSGNGVPGLILAIFFPELKVTLLDSKEKAVQFLEHVVRKLNLENAAVVKERAENFSREHREEYDYATARAVARLNTLVEICAPAVRIGGKLLFYKGPSFEEELKEARKALDELKVELEEVRRYTLKTGEQRCLLVLRKTDRSPEKYPRRVGIPFKRPLL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHRS7_MOUSE
Sequence: MSWELLLWLLALCALILPLVQLLRFLRADADLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNLKEKDILVLPLDLTDTSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYIGTVSLTKCVLPHMIERKQGKIVTVNSIAGIASVSLSSGYCASKHALRGFFNALHSELGQYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMRNNIDQSYKMPTSRCVRLMLISMANDLKEVWISDHPVLLGAYIWQYMPTWAAWLNCKLGKERIQNFKNNLDPDLPYKFLKAKKD
What is the function of this protein?
NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including steroids, retinoids and xenobiotics.  Catalyzes the reduction/inactivation of 5alpha-dihydrotestosterone to 3alpha-androstanediol, with a possible role in the modulation of androgen receptor function.  Involved in the reduction of all-trans-retinal to all-trans-retinol.  Converts cortisone to 20beta-dihydrocortisone in vitro, although the physiological relevance of this activity is questionable.  Reduces exogenous compounds such as quinones (1,2-naphtoquinone, 9,10-phenantrenequinone and benzoquinone) and other xenobiotics (alpha-diketones) in vitro, suggesting a role in the biotransformation of xenobiotics with carbonyl group.  A dehydrogenase activity has not been detected so far.  May play a role as tumor suppressor.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 7, Retinal short-chain dehydrogenase/reductase 4, retSDR4, Short chain dehydrogenase/reductase family 34C member 1, Protein SDR34C1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Note=Bound to the endoplasmic reticulum membrane, possibly through a N-terminus anchor. The main bulk of the polypeptide chain was first reported to be facing toward the lumen of the endoplasmic reticulum. However, it was later shown to be facing the cytosol.
Protein: SRRM3_HUMAN
Sequence: MSSTVNNGAASMQSTPDAANGFPQPSSSSGTWPRAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSAASVLFHTTGPAPLPPPAA
What is the function of this protein?
May play a role in regulating breast cancer cell invasiveness (PubMed:26053433).  May be involved in RYBP-mediated breast cancer progression (PubMed:27748911).
What are the official names of this protein?
Serine/arginine repetitive matrix protein 3.
What is the protein family that this protein belongs to?
Belongs to the CWC21 family.
Protein: APAH_YERE8
Sequence: MSTYLIGDVHGCLDELLALLAQVDFDPQHDTLWLTGDLVARGPASLDVLRYVRSLGPAVRMVLGNHDLHLLAVYAGISRNKPKDRITPLLEAPDADELINWLRRQPVLQVDDELKLIMAHAGITPQWDIETAQMCAREVESVLSSDSYPLFLDAMYGDMPNNWSPELTGLARLRFSTNALTRMRFCFPNGQLDMICKDTPENAPAPLKPWFELPRLVSPEYSIIFGHWASLEGKGVPEGIYGLDTGCCWGGNLTLLRWEDKRYFTQPAFKVEAEITNADEIAAAAKDPFSYL
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.