PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_CAUSK
Sequence: MTDVVPDSNAPAYSVSELAFALKRTLETSYAFVRLRGELSKVTHHGNGHVYLTIKDDKSAIDGVVWKGNVRGLGIRPEHGLEVIVTGKITTYPAGSRYQIVIETMEAAGVGALLAQLERLKAKLNAEGLFAPDRKRPLPSMPAVVGVITSPTGAVIRDILHRIRDRWPCQVLVWPCVVQGDAAAGQVSAAIRGFNALTPGGPVPRPDILIVARGGGSVEDLWAFNDEGLARTVAEGTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLAELRALVSDYDRRLNNCGGRAVEERRTRLTSAARGLPRPADLLALAQQRLDLAVRGLPRLDDLTAPAERRFKEAAARLDTALQRNTDIHARDLLKVTARLSPDTLHRQRADAGRRVGDLGRRLDLAARRVPERVAQHARLPALQDRLNAVARRRLERETDRLAGLEKLRQSLNPTRPLELGFALVHKADGGIARSASELASGERVRLQFRQGDRDAVIDGESSGVLPPSAAPAPTRPTPRPKPASSSDQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAP1_DICDI
Sequence: MQRTLSKVILNSGKNNLLKSSNLLNSNLLKATTTNIIGIKTINNNNNVNSIIGFKSLNKRYFTSNTPKVEEEDDEIAPDEAIKAEEKIKETERVIGLSEKLSFQTETQKILHIVAESLYTEKEVFIRELISNASDAIEKVRHTQLTNASMIEDASIPFEIKISTDEDNKTLIIQDSGIGMTKDEMIKNLGKIGYSGSSDFIKKLGENPDKASIIGQFGVGFYSCFMVGHTIKIYTKSATPGSKGYLWESDGTGSYSITEAEGVSRGTKIIIHLKPSSYEYSKKSIVENIIKKYSNFVGFPIALNGTTVNTIKPLWTLNKNAISEEEHKEFYQFLSKSYDTPSYRVHFSTDTPLSIRSIFYIPSQHMEKYGMGKMEPGVSLFSRKVLIQQKANGILPEWMRFVRGVVDSEDIPLNVSREHLQDNGLIQRISSVLVKRILKHLNDEAKSDPEKFNVFMTEFGGFFKEGIITDFKWKDEISKLLRFESSNGSTASKTDAVSLEQYVSRMKPEQKNIYFLSVPNRAVGLSSPYYEPFQLKDIEVIFLYNAVDEFVLTNVGHFGDKKIVSVESKEAEEFLATNQDKKTETLSQDEIDKFLSWVSTVASDKVTQAKSTTRSISSPAIIIDHESANFRRMLKMVEPGKQHETPKQVVEFNMNHPIILKLVQQTESNPTIAKLVIDQVVDNAFVSAGLIEDNREMIPRINQLLDSLLTK
What is the function of this protein?
Chaperone that expresses an ATPase activity.
What are the official names of this protein?
TNF receptor-associated protein 1 homolog, mitochondrial, TNFR-associated protein 1 homolog, Trap1 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Mitochondrion. Spore, perispore. Nucleus, nucleolus. Note=Localizes to the cortical actin cytoskeleton. Translocates to the mitochondrion during the prestarvation response and in response to differentiation. In prespore cells, colocalizes with grp94 in the prespore-specific vacuole. Found in the outermost layer of spore cell wall.
Protein: ILDR1_PONAB
Sequence: MAWPKLPAPWLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDPIFDYYSASYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPARCCCPEEALARHRYMKQAQALGPQMMEKPLYWGADRSSQVSSYPMHPLLQRDLSLRSSLPQMPMTQTTNHPPIANGVLEYLEKELRNLNLAQPLPPDLKARFGHPCSMLSSLGSEVVERRFIHLPPLIRDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRRQHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSIEARWQPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWGAHRRRSHSPHWPEEKPPSYRSLDVTPGKNSRKKGSVERRSEKDSSHSGRSVVI
What is the function of this protein?
Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (tTJs).  Crucial for normal hearing by maintaining the structural and functional integrity of tTJs, which are critical for the survival of auditory neurosensory HCs.  Mediates fatty acids and lipoproteins-stimulated CCK/cholecystokinin secretion in the small intestine.  In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1.
What are the official names of this protein?
Immunoglobulin-like domain-containing receptor 1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. LISCH7 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Nucleus. Note=Localizes to tricellular tight junctions (tTJs) between epithelial cells.
Protein: Y1517_VEREI
Sequence: MSFASASINLTHHFLIAMPGLEDAAFARSVVYLCEHSERGALGLIINKPTDITLKGLFDKVDLSLRREDLGREPVFQGGPVQTERGFVLHEPMPDEGRSATDGSAYASTMVIPGGLAMTTSKDVLEALSTGAGPRRVLITLGYSSWGGGQLESELAENAWLTVAADLSVIFDTPAPERYDRALSLLGLEVWMLSPSAGHA
What are the official names of this protein?
UPF0301 protein Veis_1517.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DF148_ARATH
Sequence: MIKSFQLSFTVLIVFTVLILGVVGNVEQKSQDWCWSIVNKDRCLQKECESLCSKKHPKGKFMCIPSTPGGPFQCHCRHPCR
What are the official names of this protein?
Putative defensin-like protein 148, Putative low-molecular-weight cysteine-rich protein 4, Protein LCR4.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFLD_NITOC
Sequence: MSNVWHNRTLALAGIIQALNSVQQIARQGNAPIDTVAASLASVFKMNPKSAEDVYGNIEGVSVGLQVLNQQLNRKSYRTDPELLRYLTNIMYLEQRLKKRPRILAQIADQIKHIEPQTEELSPADPLIIARLADTYVNTISTLTPRIQIRGEETHLRQPENIERVRALLLAAIRSAVLWRQMGGTRLHLLFQGRQLLYETHTLLKRIPRAGAA
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ZN750_XENTR
Sequence: MSLVKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITVVTDQDRIVKNPKVNSTDQKQPSNEPFAKSPVPAINGLTGLESKTQHSVAREEAKENFDLKNEAKPHVEKTTVTKEVTLPPTAIIGQINKPPSLDGVMRPSAFIPVGEHRLKGTENIKIPELSSVSTEPAKGVHSIKSAFHSLPTPWKSGLVSPDFSHKSSIPRYIRPMISEYPPQFYSETGLPAVFSPYLFPQAECENPMLSVYSAPEQRPFLPHPLQASGLPLPKPINAPFEHYRLLQQFQQNPQLHYGFYRPTEHPYFSYGLKVPPVPSLSKEHTSQSVDSPTFIYPSSHPSRLYPLEGFQKLAEIQKETSPVPAKNLDSKSDSESVKMSPRAGSAATGSPGRPSPTNFTQNSQGHEGIFDLSTKSTSDKAGKDFTSGKAVRKSTDCQTTISREHSPCFRNDEIQSHSDCYSDDAAPHDSVAPLNLSKRPEVEDRAVFDTMHNSDSNDESVGFMEIQDLPLNLSVKDSGNNQKALCADERLLLPRQVTSSPNYHFIHTVDKRVPATTGVHSLGIIENCDEQKQSAAVALCQLATSSPGVPARGTEDEFSEKETVAPEQVHPRAPAAQETEADIGARGQKRTNSKEPGKSQSSNKKHKSVDSGRMFTLRKRPRVS
What is the function of this protein?
Transcription factor involved in epidermis differentiation.
What are the official names of this protein?
Zinc finger protein 750.
What are the subcellular locations of this protein?
Nucleus.
Protein: DOK6_MOUSE
Sequence: MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDISLGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQPPLSRSSSYGFSYSSSLIQ
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK6 promotes Ret-mediated neurite growth.  May have a role in brain development and/or maintenance (By similarity).
What are the official names of this protein?
Docking protein 6, Downstream of tyrosine kinase 6.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type B subfamily.
Protein: PRMA_THESQ
Sequence: MRFKELIFPLRVEEEELVEKFYEEGFFNFAIEEDEKGKRVLKIYLREGEPLPDFLKDWEIVDEKITTPKDWIVELEPFEIVEGIFIDPTEKINRRDAIVIKLSPGVAFGTGLHPTTRMSVFFLKKYLKEGNTVLDVGCGTGILAIAAKKLGASQVVAVDVDEQAVEVAEENVRKNDVDVLVKWSDLLSDVEGTFDIVVSNILAEIHVKLLEDVNRVTHRDSMLILSGIVDKKEDMVKRKASEHGWNVLERKQEREWVTLVMKRS
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NETO1_HUMAN
Sequence: MIHGRSVLHIVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSSSKCIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHSYSQDAADACDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV
What is the function of this protein?
Involved in the development and/or maintenance of neuronal circuitry.  Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density.  Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity).
What are the official names of this protein?
Neuropilin and tolloid-like protein 1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1.
What are the subcellular locations of this protein?
[Isoform 2]: Cell membrane; Single- pass type I membrane protein. Postsynaptic density membrane. Note=Component of the postsynaptic density (PSD) of excitatory synapses. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 1]: Secreted.
Protein: RS19_ONYPE
Sequence: MPRSVKKGPIVASHLLAKIEKQKNLKNKKVIQTWSRSSTITPIFVGHKIAVYNGREHIPVYITENMVGHKLGEFSPTRTYRGHNKKDKKIQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: 4OMT2_PAPSO
Sequence: MGSLDAKPAAATQEVSIKDQAQLWNIIYGFADSLVLRCAVEIGIADIIKNNDGAITLAQLAAKLPITNVSSDYLYRMVRYLVHLNIIEQETCNGGVEKVYSLKPVGTLLLRDAERSMVPMILGMTQKDFMVSWHFMKEGLGNGSTTAFEKGMGMDIWKYLEGNPDQSQLFNEGMAGETRLLTKTLIEDCRDTFQGLDSLVDIGGGNGTTIKAIYEAFPHIKCTLYDLPHVVANSHDLPNIEKVPGDMFKSVPSAQAILLKLILHDWTDEECVNILKKCKEAIPKETGKVIIVDVALEEESNHELTKTRLILDIDMLVNTGGRERTADDWENLLKRAGFRSHKIRPIRAIQSVIEAFP
What is the function of this protein?
Involved in the biosynthesis of benzylisoquinoline alkaloids (PubMed:16034588, PubMed:22725256, PubMed:23738019).  Catalyzes the transfer of the methyl group to the 4'-hydroxyl group of 3'-hydroxy-N-methylcoclaurine to form reticuline (PubMed:16034588).  Can also use laudanosoline and, with a lower activity, 6-O-methylnorlaudanosoline and norlaudanosoline as substrates (PubMed:16034588).  Also involved in the papaverine biosynthesis (PubMed:22725256, PubMed:23738019).
What are the official names of this protein?
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase 2, 4'-OMT2, Ps4'OMT2, S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: MRAZ_DESPS
Sequence: MRKVRFRSRTEHTLDTKGRLNFPRRFSDVLESFESQDLIIAPFKTHLRIYPLAEWEELETKMHNHGGEQNLSGWVRYVVGGVVEAALDKQGRLLIPQTLRLDAGLEKNVVLNGMLSWIEIWDATAWASEQQAVRDGFEDFSEGLRNMGIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DESM_RAT
Sequence: MSQAYSSSQRVSSYRRTFGGAPGFSLGSPLSSPVFPRAGFGTKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRAPSYGAGELLDFSLADAVNQEFLATRTNEKVELQELNDRFANYFEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEEMRELRRQVEVLTNQRARVDVERDNLIDDLQRLKAKLQEEIQLREEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTFSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
What is the function of this protein?
Muscle-specific type III intermediate filament essential for proper muscular structure and function.  Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.  In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.  May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.  Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult.  Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin.
What are the official names of this protein?
Desmin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Nucleus. Note=Localizes in the intercalated disks which occur at the Z line of cardiomyocytes. Localizes in the nucleus exclusively in differentiating cardiac progenitor cells and premature cardiomyocytes. Interacts with ASB2; the interaction targets DES for proteasomal degradation (By similarity).
Protein: RS17_CARHZ
Sequence: MEKKKVQKIKIGRVVSDKMDKTVVVAVEELVSHPLYKKTIRRTKKFKAHDEHNACRTGDIVKIAETRPLSKEKRWRVVEIIERGKVLGEEENLETIEG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ZN606_HUMAN
Sequence: MAAINPWASWGALTDQSWGMTAVDPWASWALCPQYPAWHVEGSLEEGRRATGLPAAQVQEPVTFKDVAVDFTQEEWGQLDLVQRTLYRDVMLETYGHLLSVGNQIAKPEVISLLEQGEEPWSVEQACPQRTCPEWVRNLESKALIPAQSIFEEEQSHGMKLERYIWDDPWFSRLEVLGCKDQLEMYHMNQSTAMRQMVFMQKQVLSQRSSEFCGLGAEFSQNLNFVPSQRVSQIEHFYKPDTHAQSWRCDSAIMYADKVTCENNDYDKTVYQSIQPIYPARIQTGDNLFKCTDAVKSFNHIIHFGDHKGIHTGEKLYEYKECHQIFNQSPSFNEHPRLHVGENQYNYKEYENIFYFSSFMEHQKIGTVEKAYKYNEWEKVFGYDSFLTQHTSTYTAEKPYDYNECGTSFIWSSYLIQHKKTHTGEKPYECDKCGKVFRNRSALTKHERTHTGIKPYECNKCGKAFSWNSHLIVHKRIHTGEKPYVCNECGKSFNWNSHLIGHQRTHTGEKPFECTECGKSFSWSSHLIAHMRMHTGEKPFKCDECEKAFRDYSALSKHERTHSGAKPYKCTECGKSFSWSSHLIAHQRTHTGEKPYNCQECGKAFRERSALTKHEIIHSGIKPYECNKCGKSCSQMAHLVRHQRTHTGEKPYECNKCGKSFSQSCHLVAHRRIHTGEKPYKCNQCERSFNCSSHLIAHRRTHTGEKPYRCNECGKAFNESSSLIVHLRNHTGEKPYKCNHCEKAFCKNSSLIIHQRMHSGEKRFICSECGKAFSGHSALLQHQRNHSEEKLN
What is the function of this protein?
May act as a transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 606, Zinc finger protein 328.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IFEA_HELPO
Sequence: TSKISTTYEEEGRQSKIQPRAFVITRSGPTSRSSSYSARQSYGSRSSITPGVYQQLSSSGITDFRGTREKEKREMQNLNERLAGYIEKVHFLDAQVKKLEAENXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDYAEFWKSELSKCVRDIQSAYDEKIDIIXXXXXXXXXXXXXXXXXXXXXXXMQLQHVQEEVKKLRTQAGEKNAAYAEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMELEIACYRKLLEGEESRVGLRSLVEQAIGVQGRGTASLKDTIQQSTASGSMTVQRSSKGPIAFNSVDQSGSNIVIENTTSGARAKTQSLKGWRVDKTVAGRVAASIELKNYDLPPNTKYTIWAKGAKDRATADNEQIADMFSLGVG
What is the function of this protein?
Epithelial intermediate filament protein.
What are the official names of this protein?
Non-neuronal cytoplasmic intermediate filament protein A, IFA.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGA_CLOP1
Sequence: MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSKWSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTLEDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKENAEVTGSVSLEALEEVQVGENLEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIEDGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKAEGSNLSVTNSSVGDGEGLVHEIAGTEKTVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR
What is the function of this protein?
Binds carbohydrates (PubMed:16990278).  Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.  Can bind and deglycosylate O-glycosylated peptides from mammals.
What are the official names of this protein?
O-GlcNAcase NagJ, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, GH84C, Hexosaminidase B, N-acetyl-beta-D-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 84 family.
Protein: RBSD_BACAN
Sequence: MKKHGVLNSEIAAVLASLGHTDTIVIADCGLPIPDGVKRIDLAVEIGKPSFLDVLQVVADDMAIEKVTLAEEVINNNAEVNKEIELKLIEPAFEYVCHEQFKEHTKKAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA0D2_XENTR
Sequence: MANTEFYFNVDSGYLEGLVRGFKGGILRSTDYLNLAQCETLEDLKLHLQSTDYGSFLANETRQLTVSIIDQRLKDKLMAEFHYFRNHAFEPLATFLDFITYSYMIDNIILLITGTLHQRPISELVPKCHPLGSFEQMEAVNIAQTPAELFNAIIVDTPLADFFQDCLSENDMDEMNIEIMRNKLYKSYLEAFYKFCKKLGGTTEEIMCPILEFEADRRAFVITINSFGTELNKEEREKLYPTCGRLFPEGLRMLGNADDQDQVKTTAEYYAEYKALFEGVGIGTGEKTLEDKFFEHEVKMNVLAFNNQFHFGVFYAYVKLKEQECRNIVWIAECISQRHRTKINNYIPIL
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  Regulator of osteoclast fusion and bone formation (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 2, V-ATPase subunit d 2, Vacuolar proton pump subunit d 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: DDL_FUSNN
Sequence: MRIAVFMGGTSSEKEISLKSGEAVLESLQKQGYDAYGVILDERNQVSAFVDNDYDLAYLVLHGGNGENGKIQAVLDILGKKYTGSGVLASAITMDKDKTKQIAQSVGIKTPKSYRPVEEIERFPVIIKPVDEGSSKGLFLCNNKEEAEEAVKKLAKPIIEDYIIGEELTVGVLNGEALGVLKIIPQADVLYDYDSKYAKGGSVHEFPAKIENKSYKEAMKIAEKIHSEFGMKGISRSDFILSEGELYFLEVNSSPGMTKTSLIPDLATLKGYSFDDVVRITVETFLE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1036_METJA
Sequence: MSNMVEVPIFIAILSFIVMCIGELLAYYSVSLKYKYEFEAISFGFIFGVATLILIPKSYSNMFVLYVILGMITVYLIEKYLAYCPLSKKYCVECDNLEENRIKFIYPISFFIHTFIDGLIIAVSYISEIGLPLYLAILMHKLPAGFVLISPLKGVYKNPLYPGVFVSFGTVLGTIVGLVTLKDVSTKILLAFSGGVFLGAFLMLAPHIYEHKEEKTFLYILLGYILVGIIALH
What are the official names of this protein?
Uncharacterized protein MJ1036.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS3_BORPE
Sequence: MGQKIHPTGFRLAVTRNWTSRWFADDKAFGTMLAEDIRVREYLKKKLKSASVGRVIIERPAKNARITVYSARPGVVIGKRGEDIENLKADLQRLMGVPVHVNIEEIRKPETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLKANIDYGTSEAHTTYGVIGIKVWVYKGDMLANGELPPEAATPREEERRPRRAPRGDRPDGARTGRPGGRGRGPRKADAAPAPEGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RT25_PHANO
Sequence: MGRYDFRPLRVRQTAKALFDSKRNPNLPQWYEVVGNIPPGETLARPILRAPKVRHARKASKLFKPLPITYAEDKLRSDFFGDHPWELARPRLIVEDSGNDAKKYDWSKIVQPGKQLDGESVVQRQMWLMKHRNLSKASAYDAARQEFYAHRHRNEIRARIAKEEAQYVGAYFGKGPLEIGMELEDKSWEAWKRWANVQIEDEQAMRAQMFSGQSDEAPEGEGSDMSAGEYDMAVEELAGQGSIPNTPQSTVVPEGTSAPAHA
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DBNL_DROME
Sequence: MAVSFEKNRAQIVAAWKDVLDDKSDTNWSLFGYEGQTNELKVVATGDGGVDELNEDLNSGKIMYAFVRIEDPKTGLNKYLLINWQGEGAPVLRKGTCANHIRDVSNLLSGAHLTINARNEDDIDLDRLLKKLSTVSSAYSFKEPRGAMEEQKAPVGTNYTRVIPTKELNASVMQDFWKKEEAEEKLRQEAEKESKRLELQKLEQEQRSREEKEHKEREKLVISTTKLQPAHVPIKTSPQPLSPEKTAPGFANNLTDAERMRQARNQEARELIGSRVGAAKAMFTKHTSEGQLQSKLNTQPPAKPARNSIAQRINVFNQNQPQDAPVPSPPRAASPAKPLPVEAPEPVVPAPAIAPAAPVAAEVVSTIAEVEESQPVDDLPLAHESEQFSTIKRSPHSKSNSLQSQSPDETTSSNETDTAVSQEQEEEVRTKVSVTVQQSQSVKSSGMSTLERNALTDLVNEDDFICQETLGDLGQRARALYDYQAADETEITFDPGDVITHIDQIDEGWWQGLGPDGTYGLFPANYVEIIN
What is the function of this protein?
Actin-binding adapter protein.  Binds to F-actin but is not involved in actin polymerization, capping or bundling.  Does not bind G-actin (By similarity).  Does not seem to be involved in actin-based lamella protrusion during cell migration.
What are the official names of this protein?
Drebrin-like protein, Actin binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LNP_YEAST
Sequence: MFSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQSILSQWQSNLTFYGIALTVLALSYTYWEYHGYRPYLVVTALLCIGSLILFKWALTKLYAFYNNNRLRKLAKLRAIHQKKLEKLKEETHYNATSSIIQRFSSGEDQNDDAMVLLDDELNAKYQELNNLKTELEKFKKESHVKGLKKEDSDAWFDKIISVLAGGNELDSTSSLSPFKKIICPQCHWKSNCYRLASKPIIFICPHCNHKIDEVKEREDAIEAKQPAQPSQSEKEKTK
What is the function of this protein?
Plays a role in tubular endoplasmic reticulum network formation and maintenance.  Works in conjunction with the ER shaping proteins (reticulons RTN1 and RTN2, YOP1), and in antagonism to SEY1 to maintain the network in a dynamic equilibrium.  May counterbalance SEY1-directed polygon formation by promoting polygon loss through ring closure.
What are the official names of this protein?
Endoplasmic reticulum junction formation protein lunapark, ER junction formation factor lunapark.
What is the protein family that this protein belongs to?
Belongs to the lunapark family.