PharMolix/UniProtQA huggingface dataset:
Protein: NADD_STAAM
Sequence: MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RF1_YERPA
Sequence: MKSSIVAKLEALQERHEEVLAYLGDASVIADQDRFRALSREYAQLTDVTRCFKEWRSAQDDIEAAEMMLDDLEMREMAQEELKIAKARSEELEQQLQVLLLPKDPDDERDCFLEIRAGTGGDEAAIFAGDMFRMYSRYAETRRWKVEIMSASEGEHGGYKEIIAKISGDGVFGQLKFESGGHRVQRVPETESQGRIHTSACTVAVMPAIPEAELPEINAGDLRIDTFRSSGAGGQHVNTTDSAIRITHIPTGIVVECQDERSQHKNKAKAMSVLGARIRAAEMQKRQLAEASERRNLLGTGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIQPIVQEYQADQLSALSEQD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_GEODF
Sequence: MNDDILQAVYRVILERKANPSEQSYTASLMAKGIDKILKKLGEEATEVVIAGKGGAREEIIYETADLFFHTLVLLGYCDINPDEIYDELRRRFGMSGIAEKESRDR
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AABA_DICNO
Sequence: MPFLKTLFRGALCSIACGASLFCAADVYRIIRNYPELMPVSYMDEKGSPTGFETELIRKIAEQAQLDLKEEFVANFGDTLTALENGKADLAMATISVTPARQQIFDFTTPYFRVNPFAFITKDDSIKTIQDLANKKVSVWTGSNHEQKIKEIQKEGTGSVIPAKSIFLAVKAVIQGEADVAVGDDAYMLNFADRYKQHNLKAVIDRSTEPESYAIAVRKGDQALKKKIDDALLQLKRDGTIDALTKKWYPNRT
What are the official names of this protein?
Amino-acid-binding protein AabA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AGTRA_MOUSE
Sequence: MALNSSTEDGIKRIQDDCPRAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSAAKKPASCSEVE
What is the function of this protein?
Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney.  The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
What are the official names of this protein?
Type-1 angiotensin II receptor A, Angiotensin II type-1 receptor A, AT1 receptor A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRB_STRPD
Sequence: MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDHQKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALGTDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELDVLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADSLVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RMLB1_ECOLX
Sequence: MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLAEISDSERYSFENADICDAEGDGLYFGQHQLDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSGLDDEKKKNFRFHHISTDEVYGDLPHPDEVNSNETLQLFTETTAYAPSSPYSASKASSDHLVRAWKRTYGLPTIVSNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVFTICDLLDEIVPKEKSYREQITYVADRPGHDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANTNWVENVKSGAYQSWIEQNYEGRQ
What is the function of this protein?
Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
What are the official names of this protein?
dTDP-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: Y1366_MYCTU
Sequence: MVVALVGSAIVDLHSRPPWSNNAVRRLGVALRDGVDPPVDCPSYAEVMLWHADLAAEVQDRIEGRSWSASELLVTSRAKSQDTLLAKLRRRPYLQLNTIQDIAGVRIDADLLLGEQTRLAREIADHFGADQPAIHDLRDHPHAGYRAVHVWLRLPAGRVEIQIRTILQSLWANFYELLADAYGRGIRYDERPEQLAAGVVPAQLQELVGVMQDASADLAMHEAEWQHCAEIEYPGQRAMALGEASKNKATVLATTKFRLERAINEAESAGGGG
What are the official names of this protein?
Uncharacterized protein Rv1366.
Protein: YQIK_ECOLI
Sequence: MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVRTGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFFVRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENFVQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEAERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKSIAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETKAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGAAGDANTGNVGGGNLAEQALSAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVEEKAE
What is the function of this protein?
Found in membrane microdomains that may be equivalent to eukaryotic membrane rafts (PubMed:20713508).  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity (By similarity).
What are the official names of this protein?
Flotillin family inner membrane protein YqiK.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions, approximately 6 foci per cell.
Protein: ORN_STRAW
Sequence: MNDRMVWIDCEMTGLSLSDDALIEVAALVTDSELNVLGEGVDIVIRPPDAALETMPEVVRTMHTASGLLDELAAGTTLADAEAQVLAYVREHVKEPGKAPLCGNSVGTDRGFLARDMSALETYLHYRIVDVSSVKELARRWYPRAYFNSPEKSGNHRALADIRESIAELRYYREAIFVPQPGPDSETARTIAAKHVLPAQ
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_PSET1
Sequence: MDLKGKKVTLHDMSLRDGMHAKQHQISLDEMVSIATGLDQAGIPLIEVTHGDGLGGSSLNYGFPAHTDEEYLSAVVPKMTQAKVSALLIPGIGTVDHLKMAYDHGVSTIRVATHCTEADVSEQHISAARKMGLDTVGFLMMAHMISPEELLAQAKLMESYGANCIYCTDSAGYMLPDDVSTRIALLRSELNSETEIGFHGHHNLGMSIPNSLAAIEMGANRIDGSVAGLGAGAGNTPLEVFTAVLDRMAVNHGIDLYKIMDVAEDLVMPMMDQPIRIDRNSLTLGYAGVYSSFLLFAERAEKKYGVPARDILLELGRLKTVGGQEDMIDDTAMTMAKALKAAKA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RIMM_ECOSM
Sequence: MMSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHBG_YERP3
Sequence: MEKLLIVNADDFGLCKGQNYGIIDAFRNGVVSSTTAMMNSVDINHAAELSAQYPALPVGMHFVLTFGRPLTAMPSLTDANGELGKWLWQRAGAGTLDLNEIAQELECQFERFSAVFGRPPTHIDSHHHVHMLPQIYPLVAAFAREKSLPLRIDRHEVQQHGLTLDNPRSSEWFNAGFYGENLSEPSFLQLLEHADQQGVNSLEIMCHPAFIDQTLMTSGYCYPRLTELAILTSPTLKPAIAQRGYRLGSFLDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_MARN8
Sequence: MQVASVLSRGLPYIQRFTGKTVVIKYGGNAMENEDLKSSFARDVVLMKLVGINPIVVHGGGPQIGELLERLNIQSRFVNGMRVTDAETMDVVEMVLGGQVNKEIVSLINAHGGTAVGLTGKDANLIRARKLEVVNRSPELERPEIIDIGHVGEVASVNVDVIDMLTRSNVIPVIAPIGVGPDGASYNINADLVAGKVAEAMKAEKLILLTNVSGLKSKEDKVLTGLTAQQVNDLIEDGTIHGGMLPKIRCALSAVENGVRTSHIIDGRVAHACLLEIFTDEGVGTLISRN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICLN_DROME
Sequence: MVLIMRVSPPEHGLLYTANNIKLKLGDKVVGEGTVYIAQNTLSWQPTELAEGISIEWKQVSLHGISSNPRKCIYFMLDHKVEWNGVYGDPPQQAVNGRNGGGSEAEVDEGNGSDEHDEDDNFEDAVDEQFGEVTECWLMPEDIHTVDTMYSAMTTCQALHPDSANSDSEDSDPMQDAGGLEDEAMEEDDALTLGRNGVQNLSLDDDEERFEDADE
What is the function of this protein?
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins.  Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus (By similarity).
What are the official names of this protein?
Methylosome subunit pICln.
What is the protein family that this protein belongs to?
Belongs to the pICln (TC 1.A.47) family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton.
Protein: FTSY_AGRFC
Sequence: MALGFIKKVFSFGKDKAETEERPQEDAALERGNENASFEAALSDAEAHDAVDKDPVSELEMETAGGPAADEAVDVAPAEDDEEEDAPLLPGAELSGDMGLVPLSLLQAEAAAEEQGEPLPEPLDAGLDADAMDALLNEAEAASAVESPAIPPVLPKGFSSAREREEPVPVAPQVKLTWFQRLRAGLARTSSQLTTQISALFTKRKLDEDTLDELEDLLIQSDLGVETAMRITGALSSERYGKDVSGEDVARIMAGEITKVLKPVAKPLELDLSHKPHVILVVGVNGTGKTTTIGKLAAKLSGSGLKVMLAAGDTFRAAAIEQLKIWADRTGSEFIGTKLGADAAGLAYDAYEQARAQKSDVLIIDTAGRLQNKTELMAELEKIVRVLGKLDPDAPHTVLQTLDATTGQNAMNQVEIFRNVAGVSGLIMTKLDGTARGGILVAIAAKHKLPVYFIGVGEGVEDLEPFEAEDFAKAIAGV
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).  Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: RS6_TREDE
Sequence: MRNYELMTVFPVEEDLYKPGIDALHSILADFGVQIKSEEPFGDRDLAYEIKKKTKGRYVLFNIEADPAKMIELDKRFKLITQMLTYLFVRLED
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NORM_BURPS
Sequence: MSPTGFTRAAAAPPPTLSRHAADTARLAAPLAIAQLSQMAMSVTDTVLLGSLGPDALAAGGLGANLSFVVVTLLQGVLTSVSVSVAHARGAMAEDRVPHIYWTGFALSLLLAVPAFALLSFAQPLLLAFGEPAALARNVGEYAAVLRFAAPGSLIGVGLMRSFLPAIGAAKRLLWVSLAGVGVNAFLNYGLIHGAFGLPRLGFLGSATATTITIWLTAITLVALLHGRSTFRHFVAATRPRLPLMGELFGIGWPVAITYGVESTLFLATGLTVGVLGESSLAAHQIALNVASVAFMVPLAIGQAANVRVGYWAGAGAPVAARHAGFVALGLGVAFMSLSGLVLIVAPHAIVGLYLKLDDPANARTVVLATSLLGIAAVFQIVDGMQTVGSGCLRGLKDTRVPMLAAMLGYWGIGFPTGYWFAFHAGLGARGLWWGLAAGLASVAMLMTWRFHRKSAALGVRADARGQA
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPAN_STRPU
Sequence: MKLVLLLAGFAALAKCSLAAPAGVQKDIPMETSAPEKPSEATTLGLLKTPKPEPKDEEPSPGAFQGDMMLTDDQLRKVEEAIDDQKAGRKKRKATIYESQRWSYKIIPYVIESSSSGQSSLIRSAMDHWEQNTCLRFEPLTSSHSSRLGHTSYISFFRGNGCWSHVGRSFTNQQQISIGPQCGYFGTIVHEIGHAIGFHHEQSRPDRDEYINVHFENVQSGREHNFAKYTWGSVTSSNVEYDVGSIMHYGGYGFSSNGRPTITTIDPRLNSRLGQRTALSAADIELANRIYECDDVEDCSNADECLNGGYHDADCDCVCPSSYSGDLCQDGGPTVRPADCSYRFTEMTGEITSPNYPSNYEDNTACVYEIEGPYGSTIELTFLDMEIETETLCRYDAVEVRKDDINSIGEKFCGNTLPPVQISSSNQMMVSFTSDPSITRRGFKATYVIIIQTTTVFSTTTLQTTPPSTTTLQTTNPSTTTLQTTNPSTTTLQTTDTPVIGSCGGTFVGVEGRVASPNYPNDYDNSLQCDYVIEVDDGRRVELIFEDFGLEDETTCRWDSLMINLGNGIKVGMKMCGREYPAASLVSIGNRMELKLKTDGSVNDRGFVASYRAIDL
What are the official names of this protein?
Protein SpAN.
Protein: PKSB_ARATH
Sequence: MGSIDAAVLGSEKKSNPGKATILALGKAFPHQLVMQEYLVDGYFKTTKCDDPELKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGGSTVTQRLDICNDAVTEMAVEASRACIKNWGRSISDITHVVYVSSSEARLPGGDLYLAKGLGLSPDTHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSVDRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPETEKTIDGRLTEQGINFKLSRELPQIIEDNVENFCKKLIGKAGLAHKNYNQMFWAVHPGGPAILNRIEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESKKVRNMNEEENEWGLILAFGPGVTFEGIIARNLDV
What is the function of this protein?
Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones.  Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors (PubMed:19043200, PubMed:21193570).  Favorite substrates for are midchain- and v-hydroxylated fatty acyl-CoAs (e. g.  12-hydroxyoctadecanoyl-CoA and 16-hydroxyhexadecanoyl-CoA).  Required for pollen development and sporopollenin biosynthesis, the major constituent of exine in the outer pollen wall (PubMed:21193570, PubMed:20442277).  In vitro, can use 4-coumaroyl-coenzyme A as substrate to produce bis-noryangonin and fatty acyl-coenzyme A as substrate to produce medium-chain alkyl pyrones.  May play a role in both the synthesis of pollen fatty acids and phenolics found in exine (PubMed:20442277).
What are the official names of this protein?
Type III polyketide synthase B, PKS-B, Hydroxyalkyl alpha-pyrone synthase PKS-B, Protein LESS ADHESIVE POLLEN 5.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: ISPF_SHESW
Sequence: MKIRIGHGFDVHKFGEVRPLILCGVEVPYETGLVAHSDGDVVLHAVSDAILGAMALGDIGKHFPDTDTAYKGADSRVLLRHCYDLAKQRGFELGNVDVTIIAQAPKIAPHIEAMRQVLATDLMAELDDINVKATTTEKLGFTGRKEGIAVEAVVLMSRKQD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PLPR2_RAT
Sequence: MAGGRPHLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPHSGRRLSPWEDLSQAPTMDSPLEKNPRPAGRIRHRHGSPHPSRRTVPAVAT
What are the official names of this protein?
Phospholipid phosphatase-related protein type 2, Inactive phospholipid phosphatase PLPPR2, Lipid phosphate phosphatase-related protein type 2, Plasticity-related gene 4 protein, PRG-4.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 6PGL_SALA4
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEAQPRGFNIDNSGKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: NPM_MOUSE
Sequence: MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDEDDDEDDEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKPSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
What is the function of this protein?
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF.  Binds ribosome presumably to drive ribosome nuclear export.  Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids.  Acts as a chaperonin for the core histones H3, H2B and H4.  Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA.  May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules.  In concert with BRCA2, regulates centrosome duplication.  Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication.  Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.  Antagonizes the inhibitory effect of ATF5 on cell proliferation and relieves ATF5-induced G2/M blockade.  In complex with MYC enhances the transcription of MYC target genes.  May act as chaperonin or cotransporter in the nucleolar localization of transcription termination factor TTF1 (PubMed:20513429).
What are the official names of this protein?
Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Colocalizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. NEK2 is required for its localization to the centrosome during mitosis (By similarity).
Protein: PUR7_STAAC
Sequence: MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKGRLNNQITSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITKRLGFENGEVFREPLVEFFYKNDALNDPLITDDHVKLLNIASDEDIEILKSKALKINNVLKQLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGSLIETYQIFLNKLEDLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y156_LATSS
Sequence: MSLQSKHFIQALKNGVVPATGCTEPIAVAFGAATCMAQLTNREIQAIEVHVSPNVMKNALAVMVPGTGEPGLLVAAAAGAIAGDATVGLSVIEGLRATDLPTILDLAHSGKVTAKTALVPDDLYVEVTIKDLENTVTVAIAGSHTNIFSLKKDDQILIDHPRPAAHASSESKQFLQTMNFKAVWDFAMNEPLEHLRFMKEAHTLNLALAQDGFTHDYGLQLGQSINGAKRNHFGSGTENDLGNRMIAYAAAASDARMGGAQLPAMSNSGSGNQGITATIPVSVAADAVQATEEQLIRAQALSHLTALYIHSFLPVLSAFCATDSAAMGAAAGVVYLYDGTYEDACHAIQNMAGDAAGMICDGAGCACAMKVATAVSSMYRGVNLALQGIVIPNSNGIVCPTIDETIHGIGRLGTEGLRETDPVILDIMLNK
What are the official names of this protein?
UPF0597 protein LCA_0156.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.