PharMolix/UniProtQA huggingface dataset:
Protein: FLHD_YERP3
Sequence: MSTSELLKHIYDINLSYLLLAQRLINDEKASAMFRLGITDTMADALSQLTLPQMVKLAETNQLVCHFRFSDHNTIHHLTKESRVDDLQQIHTGILLSSHLLHELSLKDDSTPKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHC_NOCFA
Sequence: MQSWSDTALPTVPGAGPPLRLYDTADRQVRPVAPGATATMYVCGITPYDATHLGHAATYLTFDLVNRVLRDGGHDVHYVQNVTDVDDPLFERAARDGVDWRELGSREIELFRTDMAALRVLPPREYVGAVESVEEVVEFVQKLLANGAAYVVDDPDFPDIYFRTDATEQFGYESGYDRATMERLFAERGGDPDRPGKRDPLDALLWRAARPGEPSWPAPFGAGRPGWHIECSAIALNRLGPEFDIQGGGSDLIYPHHEYSAAHAESVVAGRRFARHYVHAGLIGLDGEKMSKSRGNLVLVSTLRKDGVDPAAIRLGLLDGHYRQDRMWTDAVLEAALARLARWRSATALSAGPAAHDTIARLRQHLADDLDSPKALAAVDNWVTEALDYGGSDSGAPAAIAEAVDALLGVRL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: ABEC2_HUMAN
Sequence: MAQKEEAAVATEAASQNGEDLENLDDPEKLKELIELPPFEIVTGERLPANFFKFQFRNVEYSSGRNKTFLCYVVEAQGKGGQVQASRGYLEDEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIIKTLSKTKNLRLLILVGRLFMWEEPEIQAALKKLKEAGCKLRIMKPQDFEYVWQNFVEQEEGESKAFQPWEDIQENFLYYEEKLADILK
What is the function of this protein?
Probable C to U editing enzyme whose physiological substrate is not yet known.  Does not display detectable apoB mRNA editing.  Has a low intrinsic cytidine deaminase activity.  May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
What are the official names of this protein?
C->U-editing enzyme APOBEC-2, mRNA(cytosine(6666)) deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: VPB49_MYCTU
Sequence: MQLGRKVTSHHDIDRFGVASTADESVYRPLPPRLRLAQVNLSRRRCRTQSDMYKSRFSECTVQSVDVSVTELRAHLSDWLDRARAGGEVVITERGIPIARLAALDSTDTLERLTAEGVIGKATAQRPVAAGRPRPRPQRPVSDRVSDQRR
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC49 (Potential).
What are the official names of this protein?
Putative antitoxin VapB49.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: PAND_BACCR
Sequence: MFRTMMRAKLHRATVTEANLNYVGSITIDEDLMDAVNIVENEKVQIVNNNNGARLETYVIKGERGSGVVCLNGAAARLVQPGDKVIIICYGLVTEEEIHTQEPKIAVLDDNNQIIEMLGAEKAGTIL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAE2_ANASK
Sequence: MSHAPRYAELRCKSCFSFLEGASHPEELVGRAAELGLSALALADVNGLYGIVRAHAEAKRQGLPLIVGAELVVAGLAPGRPARLVLLAQDREGYAGLCRLVTRAHCGEGWTGAPERRERDAVAVPFEAVAAGARGLFALYPGADGDAVARLKDAFGRRAALAVARHRVAGEEARVLAARSAGRRLGVPVAVTNDVHTHARARQVLQDVLTCVRHGTTVDRAGRRLFPNAERTLKGPEELARLWSDFPEGLAAAADIADQCRFRMEAIRGEHPLPPVVVERGALAGGVEVATSSPAQAAREGARTATPSLSLRASLPAERPAAPAIEGCAASGPGLPAAGAGGGAAAAAATDRDGALAGMSLLRELVREGARWRYGGEPPEDVARQLARELELVESLGYASYFLTVWDVVRFARSRGILCQGRGSAANSAVCYVLGITSIDPVRMGLLFERFISAERGEPPDIDVDFEHERREEVLQYVYQRYGRDRAGMVCEVITYRGKSALRDVGKALGLSLGQVDRLAKLIGTYEDLGQVGPELLAQAGLDAADSERVRMTLALARELQGFPRHLSIHVGGFVITRRPLCETVPIEPAAMPGRTIVQWDKDDLAELDLLKVDLLGLGMLTALSRALALLARHRPAPASPTAVPHPDALATIPAEDPEVYEMLGRADSIGVFQVESRAQMSLAPRLRPRNFYDLVISVAIIRPGPIQGGMIHPYLRRRDGKEQVRYPYAPLEPVLARTLGVPLFQEQAMRLAVIAAGFTPGEADELRRVMTHRRSHEKLAAMKARLVAGMAERGISGADAEEIFKQLLGFAGYGFPESHAASFALLVYASAWLKRYHPAAFACALLNSQPMGFYAPHTLVEDAKRHGVEVRGVDVGCSGWESSLEGAAPGRPAAPGETAVLRVGLHAVRGLPRAVGEAILEARAAGPFGSVAELVRRARLSRAWLVRLAEAGALGALAPDRRDAVWRSLAVEADGGDLFAGLAPPEPEVALPAASAADEVSADFATTGLSVRGHPMALVRPGLGGDRIRTARELGRLPDRAPVEVAGLVIVRQRPETARGIVFVSLEDETGIANLVVMPDVYERFRPVVRGAPFLLARGRVERSGKVVNVRVDSVAPLALAPATGARARDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCR_ECO5E
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: VF124_ASFM2
Sequence: MNLEYVHVVQKFNQVLLELTKKVCTVVGGSKPTYWYHHIRRVCSECPSMPMTMIGPYLNVYKTQILTKDKNFFMNFDPAHNEYTFIIQKLKEAARNMSEEELEQYWVKLLFLLKSYIKCKPFIN
What are the official names of this protein?
Uncharacterized protein H124R, pH124R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H124R family.
What are the subcellular locations of this protein?
Virion.
Protein: RR11_OSTTA
Sequence: MATKQRKVTQKKSRRKVQRGVVHILATFNNTLVTISDRSGLVIASSSAGACGFRGARKGTPFAAQTASEEAVRKALDYGLKYVDVMVKGPGAGREMAIRALQQLGLGVTLIRDVTPLPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS17_METEP
Sequence: MPKRVLQGVVVSDKTDKTIVVKVERRFTHPVMKKTVRRSKNYHAHDEANAAKIGQTVFIEESRPYSKTKTWKLVEDQAAAAEAAGTAA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SECY2_STAHJ
Sequence: MIKKHEYKILYKRILFTCFILIVYIFGSNISIVGSEGIYDNKDTFFKLAVSNVGGDLHTLNVFSLGLGPWLTSLVIIMLLNYRNLDQATKQTRSEKHYKERIITIVFAIFQSYFVISTYIHNNFIKDSNIILLMLILVAGTMLLVWLADQNITYGICGPMPIVLTSLIKSLFNNQHFFKLSVSVLLLILVIVTLVIALLILLFIELSEYRLNYKDIMNNSTNKTPTYLAWKLNPAGSISIMISLSVYVLLNNMINLIATLLGSNANFEFLSFANPIGIMFYIVLQIVLSYLLSRFLINTKKKADEFLKNGNYFDPIRPGRETERYLNSKARRVCWTGAILVALILAVPLYSTLLVPNLSTEIYFSMQLIILVYISINIGETIRTYLYFDRYKQILNKYW
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins.  The central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_GEOTN
Sequence: MQAKAVARTVRIAPRKARLVIDLIRGKKVGEAFAILRHTPKAASPIIEKVLKSAVANAEHNYDMDINNLVVSQAYVNEGPTLKRFRPRARGQASAINKRTSHITIVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RS21_LACLA
Sequence: MSKTLVRKNESLDDALRRFKRSVTKAGTLQELRKREHYEKPSVKRKRKSEAARKRKKY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: GATB_BURPS
Sequence: MTQWEVVIGLETHAQLSTVSKIFSGASTQFGAQPNTQACPVDLALPGVLPVLNRGAVERAIRFGLAIGATVAPRSVFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKQAYSKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKALHGLVMWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRAEIKNLNSFRFLEDAINYEVRRQIELIEDGGEVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIGADWIARVKGEMPELPAAMQQRFIEQYGVSAYDAGVLTSTKAMAEYFEALVAKAGAANAKLAANWLMGDVSSQLNRDGIDIDACPVSAAQLALVLQRIADGTISNKIAKEIFVTIWDEKAADEGAADRIIEAKGLKQISDTGALEAIIDEVLAANAKSVEEFRAGKDKAFNALVGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: NADA_NEIG1
Sequence: MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDHETAGRLKDEIKVLLKRKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVAVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKHALTGGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_FRASN
Sequence: MGEPVVVGRVGRPHGIRGDVTVDVRTDLPERRFAPGARLVRQVADGPASRPAADAAGAADAVGTAAGPGSAGDSGAARAAGPPVATVLSVVASRWHSGRLLVRFDGVTDRDAAEALRGSFLTIDSDECGPAVDPDDEDDDGELWWDRDLVGLHARTPAGDVLGEVVDVIHSPGGEILAIGRPEGGEYLVPFVREIVPTVDPAAGHIVVDPPPGLLDLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_SYNY3
Sequence: MVAVKEATNVGKITQVIGPVIDAQFPSGKLPRIYNALKVQGRNSAGNEVAVTCEVQQLLGDNQVRAVAMSSTDGLVRGMDVVDTGAPISVPVGTGTLGRIFNVLGEPVDNKGPVPAGETFPIHRPAPKLVDLETKPQVFETGIKVIDLLTPYRQGGKIGLFGGAGVGKTVIMMELINNIAIQHGGVSVFGGVGERTREGNDLYNEMIESNVINADKPEESKIALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGDLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDGTTVLSRGLAAKGIYPAVDPLDSTSTMLQPSIVGSEHYDTAREVQSTLQRYKELQDIIAILGLDELSEEDRLTVDRARKIERFLSQPFFVAEVFTGAPGKYVSLADTIKGFKAILAGELDDLPEQAFYLVGDIEEAKAKGAKLKEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: MSCL_CUPPJ
Sequence: MSMMSEFKTFAMRGNVIDLAVGVIIGAAFGKIVDSVVNDLIMPVIGRIVGKLDFSNMFVTLAEPPPGTPMTLDALKKAGVPVFAYGNFLTIVVNFVILAFIIFLMVRAFNKMRAEEPAPAEPPPPPEDIVLLREIRDSLKTRQP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_LACAC
Sequence: MTAVAVVGSQWGDEGKGKITDFLSKDAAMAVRSNGGNNAGHTIDIDGKTFKMRLIPSGIFAAKDNTVIGNGVVINPEVMFSELENLEKNGIDTSGLRISNRAHIIMPYDIKQDEYQEEAKGKNKIGTTKNGIGPTYMDKASRIGIRVCDLLEKDTFEEKLRTNLEIKNELFTKVYGKPALKFEDIFDKYYEYGQRMKKYVTDTSVLVNDALDQNKKVLFEGAQGIMLDIDEGTYPFVTSSNTISGGIASGIGIGANRLDTVIGVCKAYTTRVGAGPFPTELLDETGDRIREIAHEYGTVTGRPRRVGWFDSVALRHSKRVAGINGLSLNLLDVFSGFDKIKICTAYELDGEKIDYYPASLKELYRCKPVYEELPAWEEDITQVKTWDELPENAKKFLNRISELVGVPLVTVSVGPDREQTIVLKNPWEM
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_LEGPA
Sequence: MSSNQNIKIRLKSFDHRLIDLSTREIVDTAKRTGAQIRGPIPLPIRKEKFTVLTSPHVNKDARDQYELRTHKRLVVIVHPTEKTVDALMKLDLAAGVDVQISLDD
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FA5V_PSETE
Sequence: MGRYSVSPVPKCLLLMFLGWSGLKYYQVNAAQLREYHIAAQLEDWDYNPQPEELSRLSESDLTFKKIVYREYELDFKQEEPRDALSGLLGPTLRGEVGDSLIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANGSQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTADMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGNPDTLTRKLSFRELMKIKNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDGNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAIYPSDPKENITHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPLLVCKHKALSVKGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSAVKKDDPKFYKSNVMYTLNGYASDRTEVLRFHQSEVVQWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFIPSEVVKKKEEVPVNFVPDPESDALAKELGLIDDEGNPIIQPRREQTEDDEEQLMKASMLGLRSFKGSVAEEELKHTALALEEDAHASDPRIDSNSARNPDDIAGRYLRTINRGNKRRYYIAAEEVLWDYSPIGKSQVRSRAAKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEIQFKNLASRPYSLHAHGLLYEKSSEGRSYDDKSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPKSDKSTCEEKLIGVQSLHTFPAINGIPYQLQGLTMYKDENVHWHLLNMGGPKDIHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVGYWEPKLARLNNTGKYNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLQHSYTVEYFVTYSEDGQNWITFKGRHSETQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNRPTFRIELLGCEVEGCSVPLGMESGAIKNSEITASSYKKTWWSSWEPSLARLNLEGGTNAWQPEVNNKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIELFGCEVF
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This non-catalytic subunit is functionally similar to blood coagulation factor V (PubMed:12362232, PubMed:23869089).  It serves as a critical cofactor for the prothrombinase activity of the catalytic subunit, which is similar to the blood coagulation factor X (PubMed:12362232, PubMed:23869089).  The complex converts prothrombin to thrombin by sequential cleavage at two positions, Arg-320 followed by Arg-271 (PubMed:23869089).  Cleavage at Arg-320 produces an active intermediate known as meizothrombin (PubMed:23869089).  Meizothrombin is the 'second' substrate for prothrombinase, and it docks in an altered manner to present the second cleavage site (271) (PubMed:23869089).  Cleavage at Arg-271 releases active thrombin from its pro-fragment (PubMed:23869089).  This order of events is reversed if the protease component of prothrombinase is used on its own, suggesting that the 271 site is inherently more accessible to proteolysis (PubMed:23869089).  The complex converts prothrombin to thrombin in presence but also in the absence of membrane (PubMed:23869089).
What are the official names of this protein?
Venom prothrombin activator pseutarin-C non-catalytic subunit, PCNS, vPA, Venom coagulation factor Va-like protein.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGB3_ICRSV
Sequence: MHYIDWVILLTFAAALIVCLTPKPEPCIITVSGASATVSNCPNPELLTDLVKALKPAKPV
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: TMTC1_CAEEL
Sequence: MKKHLHHKVSGSCDPGDRSPKEKGRSQGIRNLLILISLSIIPYLSCLGGDFVFDDAESIVNNPIVNGKDPLLQIFSRDFWGRSISSSNSHKSYRPVTTFTFWLNYKLHETSTLGYHVVNIICHTVATLVFYKLGKQLEHIFDFFNIAFSASILFAVHPVHTEAVANITGRAELLMTIFSLAALILHVKNREINCKFVLLVILSTLSKEQGLMTIPIAICIDFLAHRSCRSNFVRMICLLVAIGFLRMMVNGFEAAKFTKLDNPTAFLNSKFYRMINYTYIWLYHAYLLVIPVNLCFDYSMGCISSITTMWDLRALSPVLIFTIVIIGVKFQNECRAFTLSSLMGIISFLPASNIFFTVGFSIAERVLYLPSAGFCLLCAIIFKKLSVHFKNADVLSITLILLLISKTYRRSGEWKTELSLYSSGLSVCPTNAKIHYNLGKVLGDNGLTKDAEKNYWNAIKLDPSYEQALNNLGNLLEKSGDSKTAESLLARAVTLRPSFAVAWMNLGISQMNLKKYYEAEKSLKNSLLIRPNSAHCLFNLGVLYQRTNRDEMAMSAWKNATRIDPSHSQSWTNLFVVLDHLSQCSQVIDLSYQALSSVPNESRVHMQIGSCHAKHSNFTAAENHIKSAIDLNPTSVLFHANLGILYQRMSRHKEAESQYRIVLALDSKNIVAKQNLQKLEEHNCYNSTLP
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
What are the official names of this protein?
Protein O-mannosyl-transferase TMTC1, Transmembrane and TPR repeat-containing protein F38B6.6.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: SENP8_DICDI
Sequence: MSDPLIVSYNDSAIYQSDINILKSNQWLNDSIISFYLEWLKDGGEDNKNKIPNQVLLLSPSVVFCCSFVESEQEIQLMFEQPLSLKTKEVIFFPLTNNRDPNVIGGGTHWSLLIFIKSLNKFIYYDSINSFNSSDAIFIISKFKFLLSSPPPKTNLKEFLINQKTPQQQNGYDCGLYVLSIIEELLKLIIKENENNKGEENKISYKDLLLSEFTNELLFKEITPNYIKDKRVEILNTILKLKK
What is the function of this protein?
Protease that catalyzes two essential functions in the nedd8 pathway: processing of full-length nedd8 to its mature form and deconjugation of nedd8 from targeted proteins.
What are the official names of this protein?
Probable sentrin-specific protease 8, Deneddylase, Sentrin/sumo-specific protease senp8.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
Protein: TE61_HASHE
Sequence: GMGIGINLPPCIKNGEYCNPWTGSIILGGACCGTCTDYECH
What are the official names of this protein?
Augerpeptide hhe6.1.
What are the subcellular locations of this protein?
Secreted.
Protein: CM3CH_CONRE
Sequence: RCCPMPGCFAGPFCPCC
What are the official names of this protein?
Conotoxin Reg12h.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_ECO27
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RF1_PSEU2
Sequence: MKASLLNKLDVLSDRFEELTALLGDAEVISDQTRFRAYSREYAEVEPVVALYAQLLRVQGDLEGAQALLKDSDPDMREMAVEEVRETKQQLVELEAQLQRMLLPKDPNDGRNVFLEIRAGTGGDEAAIFSGDLFRMYSRYAERRGWRVEILSENEGEHGGYKEVIARVEGDSVYGKLKFESGAHRVQRVPETESQGRIHTSACTVAVLPEPDEQQAIEINPADLRVDTYRSSGAGGQHVNKTDSAIRITHLPSGIVVECQEERSQHKNRARAMSWLSAKLNDQQTSAAANAIASERKLLVGSGDRSERIRTYNFPQGRVTDHRVNLTLYSLDEVLAGGVDAVIEPLLAEYQADQLAALGE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F262_HUMAN
Sequence: MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, 6PF-2-K/Fru-2,6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2,6-P2ase heart-type isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: TBB1_LUPAL
Sequence: MREILHIQGGQCGNQIGAKFWEVVCAEHGIDSTGRYGGDNELQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSTVCDIPPTGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEDGYEYEDEEEIGEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.