PharMolix/UniProtQA huggingface dataset:
Protein: PAPG1_ECOLX
Sequence: MKKWFPAFLFLSLSGGNDALAGWHNVMFYAFNDYLTTNAGNVKVIDQPQLYIPWNTGSATATYYSCSGPEFASGVYFQEYLAWMVVPKHVYTNEGFNIFLDVQSKYGWSMENENDKDFYFFVNGYEWDTWTNNGARICFYPGNMKQLNNKFNDLVFRVLLPVDLPKGHYNFPVRYIRGIQHHYYDLWQDHYKMPYDQIKQLPATNTLMLSFDNVGGCQPSTQVLNIDHGSIVIDRANGNIASQTLSIYCDVPVSVKISLLRNTPPIYNNNKFSVGLGNGWDSIISLDGVEQSEEILRWYTAGSKTVKIESRLYGEEGKRKPGELSGSMTMVLSFP
What is the function of this protein?
Tip adhesin component of type P pili that binds preferentially to host cell glycosphingolipids such as globotriaosylceramide.
What are the official names of this protein?
Fimbrial adhesin PapGI.
What is the protein family that this protein belongs to?
Belongs to the adhesin PapG family.
What are the subcellular locations of this protein?
Secreted. Fimbrium. Note=At the tip of P pili.
Protein: Y1806_PSEPF
Sequence: MMKGGMAGLMKQAQQMQEKMAKMQEELANAEVTGKAGGDLVTVVMTGRHDVKKVSIDPSVLPGLDEDDREVVEDLVAAAVNAAVRQIEANSQAKMGSMTAGMNLPAGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Pfl01_1806.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y2056_BACFR
Sequence: MNINTDIFKIQSNNVMPSRGKILISEPFLHDVTFGRSVVLLVDHTEEGSMGLIINKPLPLMLNDIIKEFKYIEDIPLHKGGPIGTDTLFYLHTLHEIPGTLPINNGLYLNGDFDAIKKYILQGNPIKGKIRFFLGYSGWECEQLIQEIKENTWIISKEENTYLMNEDIKGMWKEALGKLGSKYETWSRFPQVPSLN
What are the official names of this protein?
UPF0301 protein BF2056.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RLMKL_ALLVD
Sequence: MSDHIFFASAPKHLGSLLAEELTRLGMAGAAETRGGARFSGRIEDGYRACLWSRIANRILLPLAQVSLGGPDEIHDSALEIPWEDHLTPDRTFAIQFDGQLQGVTNPHFAILQVKDAIADRFNRLYGRRPSVDPDDPDLRIHLYGNRDSLSFSLDLSGESLHQRGYRDAGSAAPLKENLAAALLLRAGWPEIAAEGGALLDPMCGSGTLIIEGALIAADIAPGLLRERFGFHGWTQHDEPAWQRLLAEARLRRTAGLKRLGSLRGYDVNPNAIRTSLHHLERAGLAGLAHFERRELSDCHPGREDDEGLVIVNPPYGERLGADEDLTQLYARLGSVLKERFVGWRAAVFTSSPELGKSLGLRATRIHSLYNGPIECRLLSFQIEPRYFVSHLPRPLPPEERSPGAAMFANRLSKNLKALRKWRQRDGIDCLRIYDADLPEYALAIDLYEGERRWVHVQEYAAPPSVDPKRARQRLREALGLIPEVLEVPGEQVFLKVRRQQKGRAQYERLAETGRFHEVSEYGLRFLVNFEDYLDTGLFLDHRDVRRLIGSLSDGKRFLNLFAYTGTATVHAAKGGAASTTTVDLSRTYLEWAGRNLELNGIRGPNHQLIQADCLRWIDSMAGQRRFDLIFLDPPSFSTSKRMHGTLDIQRDHVDIIQATMRLLEPGGRLIFSNNLRRFRIDLEGLAPFEVSDISAQTLPRDFARNPRIHNCWVIQHPESASNRRNGSDDEDRHA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_RHOPB
Sequence: MNIHEYQAKAVLQPFGVSLSKGVAILKATDAEAAAKQLGGPIWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSIEEVKQYAAEMLGATLVTIQTGPAGKQVNRLYIEDGSDIEKEFYLSLLVDRVTSRISFVVSTEGGMNIEDVAHDTPEKIISFSVDPATGIMGHHGRTVAKALGLTGDLAKQAERLVAQLYAAFISKDMEMLEINPLVVTKQGELKCLDAKMSFDGNALYRHPDISALRDETEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVGGGANKEKVTAAFKIITADPNVKGILINIFGGIMKCDIIAEGVVAAVKDVGLKVPLVVRLEGTNVEAGKKIIQESGLNVLSADDLDDAAQKIVKAVKEAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RL22_CYTH3
Sequence: METTVKIKKSVLKRQKIAAAKEAAAKGAVKAHLNNVPTSTRKMRLVADLVRGQRVTLALGILKYQAKQGARKLEKLVLGSVADWQAKNSEARVEDADLYIREIFVDGGRVLKRLRTAPQGRAYRVRKRSNHITIVIDSLKELPAAPVAVVEEKEVVATAAAKPKATAKKATGEKSKAKTKAN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HSCA_BURCJ
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSVPEVLPDEAGRVLLPSVVRYLEKGGRRIGHEAKEQAATDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTIDGVKSPVEVSAEILATLRYRAEDTLGDELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNAAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHALFDHVLAQAGIDAKTLAPEDVRLLLDRVRVLKEALSSAPEAALDVTLSSGAHLAPTISHDTFASLVEPLVQRTLTPTRKALRDAQVTPADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRGTGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPIARAQEFTTFKDGQTAMAIHVVQGERELVADCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQQSGVEASVVVKPSYGLADDDIAKMLEDSFKTAEIDMRARALREAQVEAQRMLEATQAALAADGELLDADERAQVDALADALRAVAQGDDTNAIEAATKALADGTDEFAARRMDKSIKRALSGRRLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y6053_DICDI
Sequence: MEIKVLAKRKVSAKRANEILGKFILERKANEENRLFLSGNATPTEDLFQIVSNSLNKFQNHLNESINPELALTENNNNNNTTNGDSSDEALIPMSDDQPNPLKDSSNTLQIDDGDVSERYSDSVSSSTTTTIITNNKKINNNNNNKSKDIDSSNSTESENEKSVQKSKKEKESPKKLTKSKKSKKQESSDESSSESSSSSSSSSSSESSSSESESSSSSEDEKKKKKKKSSSTSSKKSSSKKRKVESSDDSDSSSSEEEKKKKKKKK
What are the official names of this protein?
Uncharacterized protein DDB_G0280579.
Protein: YJZK_BACSU
Sequence: MNEFEKWIEGRYEPHEQKQKEHEDTMGSIRKDLDAFDKAGLEFEDEIEELAEKTEALLKKHQAQYDQS
What are the official names of this protein?
Uncharacterized protein YjzK.
Protein: HISX_METKA
Sequence: MRLLVRPEEEELERVLRRSEMDVTEVLPDVERIFEDVVERGDEALLEYTERFDGVKLEAEDLRVSEDDFEVARELVDERTVEALEEAAHRIEEFHRKTLPRVDRITFDVEGTECGLTLRPIPRVGCYVPGGRAAYPSTALMTVIPARVAGCREVVVCTPPADNDVRASPEVLVAVEIAGADAVYRVGGAQAIAALAAGTETVLRVDKIVGPGNVYVTAAKLLAYSRGLTDVDMPAGPSEVFVIADDSANPDWLARDLIAQAEHDPHAAAVLATDSEEIARAVKERVEELLDAGIEREEIVLKALDRNGWIVVLDSLEECVRLANRYAPEHLQLCVENPEELLQDVENAGAVFVGHLTAVPFGDYATGPNHVLPTGGFARARGALGTWDFVKIIPIQRLREGDVERLAPIVEELAEREGLPNHAEAVRARRS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TATB_HELPJ
Sequence: MFGMGFFEILVVLIVAIIFLGPEKFPQAVVDIVKFFRAVKKTLNDAKDTLDKEINIEEIKKETLEYQKLFENKVESLKGVKIEELEDAKVTAENEIKSIQDLMQDYKRSLETNTIPNHLNEEVSNEEALNKEVSSDESPKEVQLTTDNNAKEHDKEKEHV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PRAF1_HUMAN
Sequence: MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEELQMEPV
What is the function of this protein?
General Rab protein regulator required for vesicle formation from the Golgi complex.  May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes.  In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
What are the official names of this protein?
Prenylated Rab acceptor protein 1, PRA1 family protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Protein: CML41_ARATH
Sequence: MATQKEKPSSNSFKWFSTKTLKLNLSFQNRRRSPKSNSSSTLNSPRSNSDDNNNIKSHQASKEELRQVFSHFDSDGDGKISAFELRHYFGSVGEYISHEAAQEAINEVDTDADGSLGFEDFVGLMTRRDLYGDGEVDGDGELKTAFEMFEVEKGSGCITPKGLQKMLVKLGESRTYGECEAMIKFYDIDGNGILDFHEFRQMMTV
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML41, Calmodulin-like protein 41.
Protein: HTPX_SHIBS
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_BLOFL
Sequence: MAGNSIGQYFKVTTFGESHGPAIGGIIDGVPPGLSLNAQDIQFDLNRRRPGTSRYTSPRSEPDIVEILSGVFNEKTTGTSIGLIIKNIDQRSQDYEEIKNLYRPGHADYTYEKKYGLRDYRGGGRSSARETAIRVAAGAIAKKYLYKINKINIRAYLKQIGHIHCDFKDWIYVNNNPFFCPNPEQITELDLFIRNLKKLGNSVGAKVTIIAENLPIGLGEPVFDRLDADLAHALMSINAVKGIEIGDGFSAITKLGSEYRDEITSQGFQSNHSGGILGGISTGQPIIMHIAIKPTSSIKIPGKTVTNHNQETQIITTGRHDPCIGIRIIPIAEAMVAIILMDHILRFRAQCGDRKII
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ASTB_PHOLL
Sequence: MAGFEANFDGLVGMTHHYAGLSVGNKASINNKDSVSNPRKAALQGLMKMKALADEGFIQGVLPPQQRPHIPALRNLGFVGSDEQILHKAAKYSPVLLSKLSSASSMWTANAATVSPSADSADQRVHFTVANLNNKLHRSLEIATTTAALKATFADQNYFVHHQALPQHEDFGDEGAANHNRLGGDYDSPGVQVFVYGRSVFRGGPVPKRYPARQTLEASEAIARLHRLNPAQTVFVQQNPVAIDSGVFHNDVIAVSNRNVLFHHQYAYLNQSQVLTEIRQKMAVLGQNFVSIEVPAEQISIKDAVDSYLFNSQLLSKIDGKMVLVVPEECRQHSAVWDYLQSLSAQTSAPINEVRVFDLRESMRNGGGPACLRLRVVLNDAEFRAVNPATLMNTQLYQRLTKWIEHHYRDELCASDLADPQLLCEVYTALDELTQILNLGSIYEFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: TRPD_BRUO2
Sequence: MADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAVASMRSRMIPVIAPDDAMDIVGTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSGAADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAMRHVGPSRVELGTRTIFNLLGPLSNPASVKRQLVGIFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALENGQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVVAGKAENLKDGIAQAVQSIDSGAALAVLQKVIAVSNDKPA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TD1_SOLLC
Sequence: MEVLRFTAVKSLNSCVRPEFTAMSSVIVPISTVKVSGTRKSKKKALICAKATEILSSPATVTEPLKAEPAEAPVPLLRVSPSSLQCEPGYLLPNSPVLGTGGVTGYEYLTNILSSKVYDVAYETPLQKAPKLSERLGVNVWLKREDLQPVFSFKIRGAYNMMAKLPKEQLEKGVICSSAGNHAQGVALSAQRLGCDAVIVMPVTTPDIKWKSVKRLGATVVLVGDSYDEAQAYAKKRAESEGRTFIPPFDHPDVIVGQGTVGMEINRQLKDNIHAIFVPVGGGGLIAGIAAYLKRVAPDIKIIGVEPLDANALALSLHHGQRVMLDQVGGFADGVAVKVVGEETYRLCEELIDGVVLVGRDAICASIKDMFEEKRSILEPAGALALAGAEAYCKYYGLKGENVVAITSGANMNFDRLRLVTELADVGRQREAVLATFMPEDPGSFKKFAEMVGPMNITEFKYRYNSDKERALVLYSVGLHTILELEGMVERMESADLQTINLTDNDLVKDHLRHLMGGRTNVHNELLCRFTFPEKPGALMKFLDAFSPRWNISLFHYRAQGDTGANVLVGIQVPPDEVVEFEGRADSLGYEYAMESLNEAYQLIMH
What is the function of this protein?
Has a housekeeping role in isoleucine biosynthesis (Probable).
What are the official names of this protein?
Threonine dehydratase 1 biosynthetic, chloroplastic, SlTD1, Threonine deaminase 1.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS14Z_BACHK
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RIMO_SHEAM
Sequence: MNKTVETFDPKQTTTLETPAKTLAAEAKASDGTIQGNRIGFVSLGCPKNLVDSERILTQLRIDGYEVTNSYDNADLVIVNTCGFIDAAVEESLDAVREALEENGKVIVTGCLGAKENQIREVHPDVLEITGPHSYEAVLNHVHKYVPKPEHNPFTSLIPQTGVKLTPKHYAYLKISEGCDNRCTFCIIPALRGDLDSRGVGSVLDEAKRLVESGVQEILVVSQDTSAYGKDKDGRTDFWNGMPVKQDITSLARQLGKMGAWVRLHYVYPYPWVDDLIPLMAEGLILPYLDLPLQHASPRVLKMMKRPGRVDRQLDAIKKWREICPDLVIRSTFIVGFPGETEEDFEMLLDFLREARLDRVGCFKYSEVDGAVANTLAELISEEVKEDRYERFMEVQAEISAERLARLVGRELDILIDDVDEEGAIGRSYADAPEIDGMVFINGETELTPGDMVRARIVASDEHDLWAELVALED
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_HYDS0
Sequence: MSRIGKKPIAIPNNVKVSLDGNVLTIEGPKGKLSMPVHEIVNVKIDNNQITVSKNQESPFAQAMHGTTAALIKNTIEGVSKGYSVTLEVVGLGYKAAMKGQELELNLGYSHPIYYKPPAGIKLEVKENKITVSGIDKQLVGQVAAEIIKFRKPDPYKGKGIRYEGQVLKLKPGKSAGKGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: JTX11_CHIFL
Sequence: MVKMLFFAFLPLLFMTGIAAESTISSGLNSLKTKIDAKMPSGKQLFDKVVEMQKQIDAKFSNDDERAKVMGAIGSLSTAVGKFQSGDPAKIASGCLDILVGISSVLKDFAKFSPIFSILSLVVGLFSGTKAEESVGSVVKKAVQEQSDQELQEALYGVKREYAVSKAFLDGVRNETSDLSPTEVSALAANVPIYQGVRFIAMVVQRIKYIKPKTESEIKRMLTMLELFTDLCSLRDLILLDLYQLVATPGHSPNIASGIKEVSNLGREEYKKVFEDLLKNDDKETYLFLSYLYPREKNEQSRKIFNFFDLMKVKYDDRLKQDLTGVKIFSNVHWPNYFMCSSNDYLALICTKPYGSLKLDKLNDGYYSIKTTQHDPKICHRYGNYILFTHKRNDDLEKFNFVPVKLEKREIYLLSSKESPNKFAYVPQNADGALFFVDGIPSKVGYGNQGYFTLVE
What is the function of this protein?
May cause profound effects on the cardiovascular system of anesthetized rats (at 25 ug/kg), since the fraction containing this toxin and CfTX-2 produces an initial increase in mean arterial pressure, followed by cardiovascular collapse in all animals within 1 minute of injection (PubMed:24403082).  To note, the same fraction does not induce significant change in heart rate (PubMed:24403082).  Has weak hemolytic activity (PubMed:24403082).  Is lethal to crayfish (By similarity).  Causes cutaneous inflammation in humans (By similarity).  May act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells (By similarity).
What are the official names of this protein?
Toxin CfTX-1, Toxin 1.
What is the protein family that this protein belongs to?
Belongs to the jellyfish toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: FAR2_SARBU
Sequence: TPSQDFMRF
What are the official names of this protein?
FMRFamide-2, SabFMRFamide-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_STRP7
Sequence: MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLEDLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLANTDIALIPLVSLTTGIERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SYV_CHLTA
Sequence: MNEDQFPKAYDPKSSETGVYSFWERSGIFVANASSEKPAYSIVMPPPNVTGILHMGHALVNTLQDTLIRYKRMQGFEVCWVPGTDHAGIATQTVVERHLKASLGKQRTDFSREEFLKHVWDWKEKSQNVILSQLRQLGCSCDWSRQRFTMDPGANRAVKKAFKILFDKGVIYRGYYLVNWDPILQTALADDEVEYEERDGWLYYIRYQVVNSEEFITVATTRPETLLGDTAIAVSPEDLRYSHLIGAKVVVPFVNREIPIIGDFSVDASFGTGAVKITPAHDKDDYKTGMNHQLPMINILTPTGEINENGGIFTGLSREVARENIITSLEALGLFVKKEAYSSRVGVSYRSGAIIEPYLSKQWFVSVDSFRDSLRGFVNSEEIRIFPPEFVRNYLTWVNNLKDWCISRQLWWGHRIPVWHNKHDENVICFDGEGGPEEVMRDPESWYQDPDVLDTWFSSGLWPLTCFGWPDENSLDLKKFYPTAVLVTGHDILFFWVTRMVLMCSAMVDTEPFSDVFLHGLIFGKSYREYDEKGEWFYVSGERKRDYDKGKALPKNVVAKWEKLSKSKGNVIDPIEMIEAYGADAVRLTLCSCANRGEQIDLDYHLFEEYKNFINKLWNGARFIFGHISELTSRDLEEGVNQDLLGLEDFYILDRFNELLDLIDGHYNCYSFDKIASLAYDFFKNDLCSTYLEIIKPTLFGKQDSDQQRATKRKLLATLLINILGVLHPIVPYITETLFQKLKATLGTVENGKGDSVTGHAVSMLRSEACMVAEYPKPIHVAFPQGLRESFGIAERLVYTIRNIRGEMQLDPREPLQAFVISSEKKELVDVCIPIMCALGGVKTVEQLAEAPKDSIFSLGVVEGIQVGVILPPEHLAKERVRLEKEKTRLEKSIDSVSKLLASEDFRTRANPSLVQAKKDSLRNSQRELQSILDKLASL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4844_ARATH
Sequence: MATTGTAAVATGTSTVKRKPVFVKVEQLKPGTTGHTLTVKVIEANIVVPVTRKTRPASSLSRPSQPSRIVECLIGDETGCILFTARNDQVDLMKPGATVILRNSRIDMFKGTMRLGVDKWGRIEATGAASFTVKEDNNLSLVEYELINVGGDQ
What are the official names of this protein?
Uncharacterized protein At4g28440.
Protein: GLGB_PARMW
Sequence: MGGAAVLDWMVQDGERLANCRHDHPLAILGPQPSDAGWTVRVWMPEAHSVTLLEGGREALMTAPNHPWVFETTLSHDPGSNYKVRVERGGITHEQHDPWAFRDEWMGDMDRHLFAQGNHHHIWQRMGAHLTQRDGISGVMFCLWAPHALSVSILGDLNSWDGRHHPMQQRLGGIWELFIPGLAEGSLYKYEIRTQDGHCYQKADPYGFQHEVRPDNSSVVARLDGFQWSDGSWMQRRDSSNPLEQPISVYEMHLGSWIHASAEEPWIQPDGSPRAPVPAADMKPGARLLTYAELAARLIPYVKERGFTHIELMPITEHPFDGSWGYQVTGWYAPTSRYGTPDEFRAFVDRCHAEGIGVIIDWVPGHFPKDAHGLAFFDGTHLYEHGDPRIGEHKEWGTLIFNYSRNEVRNFLVANLVFWFEQFHIDGIRVDAVASMLYRDYLRPDGEWLANEHGGRENTEAVQFLQQANHVLFQHFPGALSIAEESTTWPMVTQPTEIGGLGFNLKWNMGWMHDMLDYFELDPWFRQFHQNNITFSIWYTYTENFMLALSHDEVVHGKSHLLHKMPGDDWQKYANTRALLAYMWTHPGKKTIFMGMEFGQRAEWNVWGDLQWDLLNYEPHKGIQLLVDDLNTLYKAEPALWRDDFDQFGFQWIDCNDNRHSVISFMRRESSSGTWLVVVANFTPQSHSHYRVGVPLAGFYEEIFNTDAARYGGSNLGNMGGKPTDEWSIHGYENSLDLCLPPLSLLVFRHDPKRSLQAASASACDKADDETADTN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: CYSG_CITK8
Sequence: MDHLPIFCQLRDRDCLLVGGGDVAERKARLLLEAGARLTVNALAFIPQFTVWANEGMLTLVEGAFEESLLDGCWLAIAATDDDAVNQQVSEAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVAHYAGQLRARVKKQFATMGERRRFWEKLFINDRLAQSLANADAKAVSEITEQMLSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGRRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGVPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTAVKQRVVSGVLAQLGELAKQVESPALIIVGRVVALRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: TSHR_MOUSE
Sequence: MRPGSLLLLVLLLALSRSLRGKECASPPCECHQEDDFRVTCKELHRIPSLPPSTQTLKLIETHLKTIPSLAFSSLPNISRIYLSIDATLQRLEPHSFYNLSKMTHIEIRNTRSLTYIDPDALTELPLLKFLGIFNTGLRIFPDLTKIYSTDIFFILEITDNPYMTSVPENAFQGLCNETLTLKLYNNGFTSVQGHAFNGTKLDAVYLNKNKYLTAIDNDAFGGVYSGPTLLDVSSTSVTALPSKGLEHLKELIAKDTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSIRNLRQRKSVNILRGPIYQEYEEDPGDNSVGYKQNSKFQESPSNSHYYVFFEEQEDEVVGFGQELKNPQEETLQAFESHYDYTVCGDNEDMVCTPKSDEFNPCEDIMGYRFLRIVVWFVSLLALLGNIFVLLILLTSHYKLTVPRFLMCNLAFADFCMGVYLLLIASVDLYTHSEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHAYTIMAGGWVSCFLLALLPMVGISSYAKVSICLPMDTDTPLALAYIVLVLLLNVVAFVVVCSCYVKIYITVRNPQYNPRDKDTKIAKRMAVLIFTDFMCMAPISFYALSALMNKPLITVTNSKILLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGICKRQAQAYQGQRVCPNNSTGIQIQKIPQDTRQSLPNMQDTYELLGNSQLAPKLQGQISEEYKQTAL
What is the function of this protein?
Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin.  Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Plays a central role in controlling thyroid cell metabolism.
What are the official names of this protein?
Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.