PharMolix/UniProtQA huggingface dataset:
Protein: Y2648_METMA
Sequence: MPEPARKPVKEPEEPAGTPIKEHFQLKETIVTIAACDRKYIEAAKDAIRTHRAVLETYILSDPYFQITLEPYECPENAPEVVRRMIKAGNTIGIGPMSAVAGTISALAVEAMVKAGAKYAIVDNGGDIALINDRPVVVGIYSGQSPIRNLGLVFEPRDSITGVCTSAGTVGPSISFGMADAAAVFSDDVSLADAAATALGNEVGTGKEAVEISFRAIRGIPGIKGALVIQGEYIGMWGDLPEITRADVRYEYITKA
What are the official names of this protein?
UPF0280 protein MM_2648.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: FKB11_MOUSE
Sequence: MTLSPLLLPLQLLLLLLFSGAVCRAEAGPETESPVRTLQVETLVQPPESCTESAAIGDTLHIHYTGSLVDGRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAVIPSHLAYGKRGYPPSIPADAVVQYDVELIALIRANYWQKLLKSILPLVGIAMVPALLGLIGYHLYRKASRPKVSKKKLKEEKRNKSKKK
What is the function of this protein?
PPIases accelerate the folding of proteins during protein synthesis.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase FKBP11, 19 kDa FK506-binding protein, 19 kDa FKBP, FKBP-19, FK506-binding protein 11, FKBP-11, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KEFB_SALEP
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVELCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y802_STAEQ
Sequence: MGQNDLVKTLRMNYLFDFYQSLLTNKQKNYLELFYLQDYSLSEIADTFEVSRQAVYDNIRRTGDLVEDYESKLRLYQRFEKRRELYNLMKQSLNQPELLKQYITQLEELE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SERP0802.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: YIDC_RALSO
Sequence: MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAAPAAAGSQAAPATGAVSQTPASEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVLFDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGGEVSLTLTADKGGAKLAKTYVFKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHKITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQALGTVAPGASVSATARLFAGPQEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLLGNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMTAIRERHKGDPQKMNQEMMTLYRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILMAVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSINRMLGTNKKAAAAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_OENOB
Sequence: MANTQYAGTGRRKVSVARVRLTPGSGKITINNRSFEEYIPAANLRAVVIQPFAVTSTDGTYDVNVNVVGGGFAGQAGATRHGIARALLQVDPDFRPALKSAGLLTRDSRMVERKKPGLKKARRASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SUCD_METTH
Sequence: MRGSIMILLDEDTRCLVQGITGKQGSFHTRQMLEYGTRIVAGVTPGKGGQEFLGVDVYNSVEEVTEEMDVNASIIFVPAPFAKDAAFESIKHLDLVVIITEHIPVHDSMQIMEYASRMGKTVIGPNTPGIITPGIGKLGIMPTHIFTEGTIGIVSRSGTLTYEFAAQLTEAGFGQSTCVGIGGDPVTGLGFVDVLERFEDDPGTDAVVLIGEIGGDAEERAASYIEQMSKPVFAFISGATAPPGKRMGHAGAIIEGGTGTASSKREALEAAGAVVVDRPSAIVDEIRAQLGVR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
Protein: NM111_VANPO
Sequence: MSVTNSNRKRSLSEVSEGSDPEAPAKTRNSYTTDEIVMVEEVDSEIPVNISSYGDAETYLKWQNTIAKVVKSVVSIHFSQVAPFDSDNAVVSQATGFVVDASLGIILTNRHVVGPGPFVGYAVFDNHEECDVTPIYRDPVHDFGFLKFDPTKIKYMNIQALELKPSLAKVGSEIRVVGNDAGEKLSILSGFISRLDRNAPDYGELTYNDFNTEYIQAAAAASGGSSGSPVVNSDGYAVALQAGGSTEASTDFFLPLDRILRALKCLQSNKPITRGTIQLQWLLKPFDECRRLGLTADRESQARAQFPDKIGLLVAETILREGPSDIKIKEGDTLISINGELISSFIQVDDILDESIGKEIEIIIQRGGIEHTVKCEVGDLHSITPDRYVEVCGATFHELSYQMARFYGMPVRGVFISSASGSFNIDANERVGWIVDSIDNKETPNLDTFIEVMKTIPDRQRVTLRYHHLTDQHTIHVTSIYIDRHWCSEFRLYKRNDVTGIWDYENVAEPIKAEELKPHAAKFIDIPIDIPEIATLSHSLCMVSTVSAIPLDSLPVENVKTSGLVIDAEQGYIIVSRRAVPHDCLDVFVTFADSVMIPASIVFLHPTKNYAIIKYDINLVNANIITPKLSNTPMKRGDRTRFIGFTHNNRLVTSETSVTDISSISIPSNIIPRYRATNLEAISIDCNVSTKCNSGILTDNDGTIRALWLSFLGERQDNKDKIYLMSLDITDCKEVIELLKEGKKPKVSIIDAGFGAISILTARIRGVPEEWIKKMELQSENRLQFISVSRVSFTEEPVKLQTGDVILAVNDKLVTEMSQLDGVVSTADDEESQTLRFKVVREGKIIDLNIKTIYVKETSQIAVFSGSILQPPHHAVWQSMMNIPSGVYCTFRGESSPALQFGISATNFITHVNETETPDLDTFLKVIKQIPDNTYCKMRLMTFDNVPFAISLKTNYHYFPTTELKKNIESGKWIENELNKTEEKKIIKSD
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease NMA111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANC_BURP1
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSIRRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHC_MOUSE
Sequence: MSTVKEQLIQNLVPEDKLSRCKITVVGVGNVGMACAISILLKGLADELALVDADTNKLRGEALDLLHGSLFLSTPKIVFGKDYNVSANSKLVIITAGARMVSGETRLDLLQRNVAIMKAIVPGIVQNSPDCKIIIVTNPVDILTYVVWKISGFPVGRVIGSGCNLDSARFRYLIGEKLGVNPTSCHGWVLGEHGDSSVPIWSGVNVAGVTLKSLNPAIGTDSDKEHWKNVHKQVVEGGYEVLNMKGYTSWAIGLSVTDLARSILKNLKRVHPVTTLVKGFHGIKEEVFLSIPCVLGQSGITDFVKVNMTAEEEGLLKKSADTLWNMQKDLQL
What is the function of this protein?
Possible role in sperm motility.
What are the official names of this protein?
L-lactate dehydrogenase C chain, LDH-C, LDH testis subunit, LDH-X.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBX2_HUMAN
Sequence: MLPSAVAAHAGAYWDVVASSALLNLPAAPGFGNLGKSFLIENLLRVGGAPTPRLQPPAPHDPATALATAGAQLRPLPASPVPLKLCPAAEQVSPAGAPYGTRWAFQVLSPSADSARLPGRAPGDRDCTFQPSAPAPSKPFLLSTPPFYSACCGGSCRRPASSTAFPREESMLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCIQEVGLQEDPLSRSALGFPSPCPSIWDVPQQHSSPRWRENSPEPSERLIQESSGAPPPEANSLQGALYLCSEEEAGSKGVLTGAV
What are the official names of this protein?
Homeobox protein DBX2, Developing brain homeobox protein 2.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROFA_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEDHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLVEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PSBF_SYNJB
Sequence: MATKSDEPVFYPVFTVRWLAVHTLAIPTVFFLGAIAAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS5_RICBR
Sequence: MSKVRKNEEALSEVLVDVNRVTKVVKGGRRFAFSAYVVVGDKAGRVGAGHGKAKEVNEAREKAKQAAKKKMMKVSLYQNRTIHHDVIGRSGAAKVVLRRAKAGTGVIAGGSMRAIFDSLGVHDIVAKSIGSTNVYTMIAATFDALKKLSSPKSIAARRDKKMNEIFIKSSDIQVNE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GL_EBVB9
Sequence: MRAVGVFLAICLVTIFVLPTWGNWAYPCCHVTQLRAQHLLALENISDIYLVSNQTCDGFSLASLNSPKNGSNQLVISRCANGLNVVSFFISILKRSSSALTGHLRELLTTLETLYGSFSVEDLFGANLNRYAWHRGG
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.  Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL.  The heterodimer gH/gL targets also host EPHA2 to promote viral entry.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: RFBA2_KLEPN
Sequence: MSLKMKYNLGYLFDLLVVITNKDLKVRYKSSVFGYLWSIANPLLFAMIYYFIFKLVMRVQIPNYTLFLITGLFPWQWFASSATNSLFSFIANAQIIKKTVFPRSVIPLSNVMMEGLHFLCTIPVIIAFLFVYGMRPSLSWLWGIPIIAIGQVIFTFGISIIFSTLNLFFRDLERFVSLGIMLMFYCTPILYASDMIPEKFSWIITYNPLASMILSWRELFMNGVLNYEYISILYITGFILTIVGLAIFNKLKYRFAEIL
What is the function of this protein?
May form an ATP-driven O-antigen export apparatus, in association with RfbB.
What are the official names of this protein?
O-antigen export system permease protein RfbA.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK_RHIL3
Sequence: MVIGLSHYLTVSAILFTLGVFGIFLNRKNVIVILMSIELILLAVNINMVAFSSFLNDIVGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL32_DESAL
Sequence: MALPKHKKSKSKRDKRRTHQKLTAPNVVSCPQCGDPKLPHHICPSCGTYKGRTLIETD
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLYA_PROM1
Sequence: MKCDPSIAKLINNELSRQETHLELIASENFASKAVMEAQGSVLTNKYAEGLPNKRYYGGCEYIDGIEQLAIDRAKNLFGANWANVQPHSGAQANFAVFLSLLKPGDTIMGMDLSHGGHLTHGSPVNVSGKWFKTCHYEVDKKTEMLDMDAIRKKAIENQPKLIICGFSAYPRKIDFKAFRSIADEVNAYLLADIAHIAGLVASGLHPSPIPYCDVVTTTTHKTLRGPRGGLILSKDEEIGKKLDKAVFPGTQGGPLEHVIAAKAVAFQEASAPEFKIYSQKVISNAQVLSNQLQKRGISIVSKGTDNHIVLLDLRSIGMTGKVADQLVSDIKITANKNTVPFDPESPFVTSGLRLGSAALTTRGFNEQAFEDVGNIIADRLLNPNDEDIKENSINKVSELCNKFPLYSENI
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPK5_PLAF7
Sequence: MKETEVEDMDTNRKDGKIKKKEKIVNMKNEEVKSTTKSTLADSDEDYSIITLCTKCLSKKLEDNKNRIILDSKAFKDNRLKGRCSVSSNEDPLDNKLNLSPYFDRSQIIQEIILMNNDELSDVYEIDRYKLGKGSYGNVVKAVSKRTGQQRAIKIIEKKKIHNIERLKREILIMKQMDHPNIIKLYEVYEDNEKLYLVLELCDGGELFDKIVKYGSFSEYEAYKIMKQIFSALYYCHSKNIMHRDLKPENILYVDNTEDSPIQIIDWGFASKCMNNHNLKSVVGTPYYIAPEILRGKYDKRCDIWSSGVIMYILLCGYPPFNGKNNDEILKKVEKGEFVFDSNYWARVSDDAKDLICQCLNYNYKERIDVEQVLKHRWFKKFKSNNLIINKTLNKTLIEKFKEFHKLCKIKKLAVTCIAYQLNEKDIGKLKKTFEAFDHNGDGVLTISEIFQCLKVNDNEFDRELYFLLKQLDTDGNGLIDYTEFLAACLDHSIFQQDVICRNAFNVFDLDGDGVITKDELFKILSFSAVQVSFSKEIIENLIKEVDSNNDGFIDYDEFYKMMTGVKE
What is the function of this protein?
Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:20466936, PubMed:31915223).  Plays a central role in host erythrocytes and hepatocytes infection cycles (PubMed:20466936, PubMed:29487234).  During the liver stage, involved in sporozoite motility and thus in sporozoite invasion of host hepatocytes, probably together with CDPK1 and CDPK4 (By similarity).  Involved in merosome egress from host hepatocytes, probably together with CDPK4 (By similarity).  Required for the release of hepatic merozoites from merosomes in the host blood stream (By similarity).  During the asexual blood stage, required for merozoite egress from host erythrocytes by triggering microneme secretion (PubMed:20466936, PubMed:29487234).  Phosphorylates transporter NPT1 at late schizont stage (PubMed:31915223).
What are the official names of this protein?
Calcium-dependent protein kinase 5, PfCDPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, microneme membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=During the late stages of schizogony, localizes to the cytoplasm in immature daughter merozoites, co-localizes with AMA1 to a subset of micronemes and to the apical region in maturing daughter merozoites, and near the plasma membrane in mature daughter and free merozoites.
Protein: Y4JK_SINFN
Sequence: MIVLDTNVISELWKAEPDRAVLAWIDAQMIETLYLSAITVAELRFGLAAMPAGKRRTIFQNRLEGEVLPALAGRVLPFDLDASRSYADLMAQAKTSGKVIGKADGYIAATAVAHGFMVATRDTSPFEAAGLDIINPWEPA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Involved in plasmid stability (Probable).
What are the official names of this protein?
VapC ribonuclease Y4jK, RNase Y4jK, Putative plasmid stability protein Y4jK, Toxin Y4jK.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: RAPA_ERWT9
Sequence: MPFTLGQRWISDTESELGLGTVVAVDTRMVTLLFPATGENRLYARNDSPITRVVFNPGDTITSHEGWQLDVDEITTANGVVSYIGTRLDTSETGVVLREVMLDSKLVFGKPQDRLFAGQLDRMDRFALRFRARKYQSEQYRLATSGLRGMRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMIIHQQLQAGRAERVLIVVPETLQHQWLVEMLRRFNLRFALFDDDRYAQAQLDSDNPFDTEQMIICSLDFVRRNKQRLEKLADAEWDLMVVDEAHHLVWSEDAPSREYQVIEQLAEQVPGILLLTATPEQLGMESHFARLRLLDPDRFHDFAQFVEEQKHFSPIADAVTLLLADQKIGNDELNLLNDLMGEQDIEPLLQTANSDREGKLAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHQIRLPLPTQYQTAIKVSGIMSARKTADERAQDMLYPEQIYQEFEGDSGTWWNFDPRVEWLMGYLTSNRDKKVLVICAKAATALQLEQVLREREGIRAAVFHEGLSIIERDRAAAWFASEEDGAQVLLCSEIGSEGRNFQFASQMVMFDLPFNPDLLEQRIGRLDRIGQVHDIQIHVPYLEKTAQAVLVQWYHEGLDAFEHTCPTGRAVYDSVYTQLIAYLAAPENSEGLEAFIQHCRKQHDTLKAQLEQGRDRLLELNSNGGEKGQALADMIAEQDNNIELVNFALNLFDIVGINQEDRSDNLIVLTPGDHMLVPDFPGLPEDGCTITFDRNQALSREDAQYVSWEHPIIRNGLDLILSGDTGSCAISLLKNKALPVGTLLVELIYVVEAQAPKHLQLTRFLPPTPIRMMVDRKGNNLAAKVEFESFNRQLNAVNRHTGSKLVNAVQSDVHEIITLSEDQAAAEARKVIDAARQEADEKLSAELSRLQALSAVNPNIRQDEIDALESNRQQVLSNLDEAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: DPO3E_BUCAI
Sequence: MNRKRTIILDTETTGINQTSLPHINHRIIEIGAVEIIDRCFTGNNFHVYIQPGRSIESGALKVHGITNKFLLDKPIFKDIADSFLNYIKNSILVIHNASFDVGFINQELEILNKKIKINTFCSIIDTLKIARELFPGKKNTLDALCTRYKINKSHRNLHSAIVDSYLLGKLYLLMTGGQDSLFSDNTINYKENFKKLKKNIQLKNNTLRILHPTLKENDLHEKYLQYMKDKSTCLWN
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).
What are the official names of this protein?
DNA polymerase III subunit epsilon.
Protein: IBBA7_HYAOR
Sequence: QTWPPVEDRPHCKRCVACTLMWPPEANRCVCGDLVPKCHKGCSQCEKADTRSGRPLYKCLSFEYYNCAAD
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Strongly inhibits trypsin (Ki = 7. 1 nM) and almost completely inhibits elastase (PubMed:33666645).  Also inhibits chymotrypsin (Ki = 19 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor A7, HOSPI-A7.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: RSMA_ARTS2
Sequence: MTKPIPAASGTAPAALFGASDVRRLAEEIGVRPTKTLGQNFVIDGNTIRRIVAAADIHADETVLEVGPGLGSLTLGLLDAAKSVVAVEIDPVLAAKLPGTVQQWRPGAAKDFHLVLADAMKVTELPVEPTALVANLPYNVAVPVVLHLLQHFPSLRHGLVMVQDEVADRLAAGPGSKTYGVPSVKAAWYSSMRKAGVIGMNVFWPAPKIHSGLVAFTRREPPVTSATREQVFAVIDAAFAQRRKTLRAALAGWAGSAAEAEQCLLAAGVDPTARGEVIDIAAFARIAEARQDRQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_NOSS1
Sequence: MATTERKPLLLDFEKPLAELANRIDQIRQLAEENGVDVSGEIRKLETRAMQLREEIFSTLSPSQRLQVARHPRRPSTLDYIQAISDEWMELHGDRCGGDDPALIGGVARLGGKPVVILGHQKGRDTKDNIARNFGMATPGGYRKAMRLMEHANKFSMPILTFIDTPGALPTVVAERQGAGEAIAYNLREMFSLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSVYTVATPEACAAILWKDASKSPQAAVALKIVSHDLKNLGIIDQILPEPTGGAHSDPLTAATTLKQALLDNLDELDRLTSQERRQLRYDKFRKIGVFTEVAH
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.