PharMolix/UniProtQA huggingface dataset:
Protein: SLX1_RAT
Sequence: MGHAARPGRFFGVYLLYCQNPRHRGRVYVGFTVNPARRVRQHNAGRKKGGAWRTSGRGPWDMVLILHGFPSAVAALRFEWAWQHPQASRRLTHVGPRLRSEASFTFHLRVLAHMLRVPPWVRLPLTVRWLRPDFRHELCPAPPPHMPIAFGPPPPQPLVPKRPAASEADSERRLDLGAKASCTLCARMLQDEEGPLCCPHPGCPLRAHIICLAEEFLQEEPGQLLPLEGHCPSCKKSLLWGNLVGQCHEDTEEEEVDLELEEEHWTDLLET
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs).  Resolves HJs by generating two pairs of ligatable, nicked duplex products.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1, GIY-YIG domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPAB3_CAEBR
Sequence: MAGIIFDDMFSVKSVDPDGKKFDRVSRYFCDAESFKMELIIDINSQIYPLKQNDKFRLVLATTLREDGLADEGEYDPKAEYPRIKQYEYVMYGKVYRLEDDDSGTDGGQLAAYASFGGLLMRLKGEAINLHGFEVDMNLYLLMKKTDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerases I, II, and III subunit ABC3, RNA polymerase B subunit 8, RPB8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECX_SALPA
Sequence: MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWFHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGISRESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_NEIM0
Sequence: MTVSPVALRRKTECKPHPTARYWKKCDVEALFGLPFLELVHQAAEVHRQNFNPREIQLSTLLSIKTGGCPEDCAYCPQSAHHNTNLGKEQMMDVDEIVEKAKIAKSRGASRFCMGAAWRGPKPKDVETVSAIIKAVKGLGMETCGTFGMLEEGMAEDLKEAGLDYYNHNLDTDPDRYNDIIHTRRHEDRMDTLGKVRNAGLKVCCGGIVGMNETRAERAGLIASLANLDPQPESVPINRLVKVEGTPLDDAEDLDWTEFVRTIAVARITMPQSYVRLSAGRSNMPEAMQAMCFMAGANSIFYGDKLLTTGNPDEDGDRILMEKLNLYPLQFELEGEVAEVEKASGIKVDY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CH10_XANC5
Sequence: MSIKPLHDRVVVKPIEADEVSAGGIVIPDSAKEKSTKGEVVAIGAGKPLDNGSLRAPVVKVGDKVIYGQYAGSSYKSEGVEYKVLREDDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y976_HAEIN
Sequence: MLYQILALLIWSSSLIVGKLTYSMMDPVLVVQVRLIIAMIIVMPLFLRRWKKIDKPMRKQLWWLAFFNYTAVFLLQFIGLKYTSASSAVTMIGLEPLLVVFVGHFFFKTKQNGFTGYSVQWHLLAWQF
What are the official names of this protein?
Uncharacterized protein HI_0976.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAD_CLOB1
Sequence: MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKKHSNVEVQCFSGLLIDFMKEKKSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTNAKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHKKECI
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATNG_SHEEP
Sequence: ENEDPFYYDYETVRNGGLIFAALAFIVGLVIILSKRFRCGAKKKHRQIPEDGL
What is the function of this protein?
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit gamma, Na(+)/K(+) ATPase subunit gamma, FXYD domain-containing ion transport regulator 2, Sodium pump gamma chain.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: SYGA_STRT2
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEKLGINPLEHDVRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSDQDMLLENFEKFEKEAGRALELGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGYPLLDEATRKKLLAEEEE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_MYCA9
Sequence: MSVATRVIACLDVDDGRVVKGVNFENLRDAGDPVELAAAYDAEGVDELTFLDVTASSSGRATMLDVVRRTAEQVFIPLTVGGGVRSVDDVNVLLRAGADKVGVNTAAIARPELLAELAQRFGSQCIVLSVDARRVRDGDVPTSSGWEVTTHGGRRGTGIDAIEWTSRGAELGVGEILLNSMDADGTKAGFDLEMIAAARAAVDVPVIASGGAGAIGHFAPAVQAGADAVLAASVFHFRELTIGEVKAAMAAEGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_SINFN
Sequence: MKGSRSKQPEITPDMLLRAYSIGLFPMADSANDPELFWVEPEIRGVLPLDRFHVSHSLAKRIRKRPYEIRFDTAFEAVIEGCAKPAPGRPTTWINDKIRSLYAALHRMGYAHSVEAWEGDRLVGGLYGVSLGAAFFGESMFSLRTDASKICLVHLVERLRARHFQLLDTQFTTEHLKSFGAVDVPKAEYDLLLARAIASPNLEF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAR1_ORYSJ
Sequence: MRRLGLSLHHDTSPSFAALACNQRPPPNGTVHACSKSRPPQLEPGKVGKKPIKKTMRIARIPTSIPPHLRLPLDLSAVSPMGSASEHDVREHLLDVDGVGEEGAAAAAGPKIRVRGLTRRSEARGEEILRGVDLDVPRGVVVGVIGPSGSGKSTLLRALNRLWEPAPGAVLLDGVDICGIDVLALRRKVGMLFQLPAMFDGTVADNVRYGPQLQGKKLTDAEVQSLLSLADLDPALCSKPASELSVGQAQRVALARTLANDPEVLLLDEPTSALDPISTQNIEEAIVRLKKTRGLTTVMVSHSVKQIQRIADLVCLLVAGEVVEVLPPSELSEAKHPMARRFLELS
What is the function of this protein?
Associates with STAR2 to form a functional transmembrane ABC transporter required for detoxification of aluminum (Al) in roots.  Can specifically transport UDP-glucose.
What are the official names of this protein?
Protein STAR1, ABC transporter ABCI.12, OsABCI12, ABC transporter I family member 12, Protein ALUMINUM SENSITIVE 1, Protein SENSITIVE TO ALUMINUM RHIZOTOXICITY 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCI family.
What are the subcellular locations of this protein?
Membrane.
Protein: GCS21_MYCVP
Sequence: MSSLAADQRADGRIDFVGSVRPTVGVEWEFALVDATTRDLSNEAASVIAEIGENPRVHKELLRNTVEVVTGICANAGEAMEDLASTLRPVREVVRERGMDLFCAGTHPFADWSVQKLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGVSSAHKVMPIITALLHQYPHLLALSASSPYWDGEDTGYASNRAMMFQQLPTAGLPFHFQEWREFERFVSDQKKTGIIDHMNEIRWDIRPSPHLGTIEVRIFDGVSNLHELSALVALTHCLIVDLDRRLDAGESLPVMPPWHVQENKWRAARYGLDAIIILDADSNERLVTEDLDDLLERLQPVAKRLSCVEELSRVPDIYHNGASYQRQRRVAEEHDGDLRAVVDALVSELVL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: HSP1_LAGFA
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRYRGSRRSRSRRRGRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL22_CHICK
Sequence: MAPVKKPAAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEEED
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_THEMA
Sequence: MPRKRLTGIVVSDKMDKTVVVAVEKLVQHPLYKKYVKRTKKYHAHDERNECKIGDVVEIEETRPLSKTKRWRVVRIIQRFEPERVVKEKEDIQEEIEAVEGKGGVES
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PSBN_PROM4
Sequence: METSSLALQLAIIVLVVLLGLTGLGVYMAFGPAAKGLDDPWDEHDD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CYB_MUNMU
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDVDKIPFHPYYTIKDILGALLLILFLMLLVLFVPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALISSILILIFMPLLHTSKQRSMIFRPLSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NTAQ1_ARATH
Sequence: MSGVTSEPIAMDATRFQHTPYYCEENVYLLCKTLCENGVAEATCSDLFVVFISNEKKQVPLWHQKASTRADGVVLWDYHVICVQRKKESDSEPLVWDLDSTLPFPSPLASYVTETIQPSFQLFAEYQRFFRIVHAPLFFKHFASDRRHMKEPDGSWTAQPPPYEPIVAQDGILHNLSEYIAMSGADTLSSLDPETVTAAISQKLGVVVSHTQLQDLFTKLP
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation (PubMed:30117535).  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule (PubMed:30117535).  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position (PubMed:30117535).  Involved in immune response (PubMed:30117535).  Controls the expression of specific defense-response genes, activates the synthesis pathway for the phytoalexin camalexin, and influences basal resistance to the hemibiotroph pathogen Pseudomonas syringae pv tomato (Pst) (PubMed:30117535).
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: CMOA_NITOC
Sequence: MKGVDDTDLVPDSAGEGSRVFHDQLFAESNSAIEDFRFDGATASVFDDMVHRSVPFYDEMQRMTEEITADFAVPGTNLFDLGCATGTTLLRLDAALDPRVHFIGVDNSLEMLEKGRQKFLARKSTRRCEFMAADLHRERIIEDASVVIMILTLQFIRPLHRTRMLQGLIEGMNEQGCLIIFEKVTLNDSLFNRLFIRYYYNMKKRQGYSDVEIARKREALENVLIPYRPEENYELLASVGFSHVEEFFRWYNFSGILAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: MCL1B_XENLA
Sequence: MDFSSCNNHYFYDVDMKEDFYRCIAPSEDIWKKFELVPGFPLSSGGCPGGGGTDWAAEMMDLGWESPVKLTGLSSVVLLRDCMWSGFSTRERLEKVIHERLSTGSPRVTNTQKPVADNETSEPGVDSIEQNATPLVVPTPIPEKVPNSSGSESTSDSEEDEIDVVTVEKRKSYGGRQPVTITVRADPTATKLFHISIHQQQHNYAARLPPEPNTMSPQHNFHSTVKEEPGEVTSPPELQPCSPQMPDSPLASGSSDSEDLAKRKNHNYLERKRRNDLRSRFLALREEVPSLSRSTKTPKVVVLSKATEFLKGLVIQEQQLTAEKLKLWSRHQQLLRRISQLKGR
What are the official names of this protein?
Protein L-Myc-1-B, Protein L-Myc 2, xL-Myc2.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLCDH_METAR
Sequence: MKAAAITPGKKDSLRVIDVDRPRPGAGEVLVRMLEAGVCGTDEELNLGIIGEAPAGSDYLIIGHENLGVVEEAGKDVRAFRKGDLVVATVRRSCPGMCFACRTGQPDMCDSDDYLERGIKGMHGYMAEYYTERPENLIPVPQSLRKVAVLLEPLSIVEKGIEQAFKIQERMIWRPRRALVAGAGPIGLLAALILRDVGLEVSTFATRSRESLKARIAEAAGIEYFNVKETPIEQIAELQGPLDMIVEATGSSEIAFKAIGLTDSNGIVCLTGLSPEQRTHSVCTDCVNQDLVMHNKAVFGTVSSNRVHFERGIDRLTSIERRWPGLLERMFSRRVRLENVKEGLKGDKEDVKVLVEIGA
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone.  Can utilize both NAD(+) and NADP(+) as electron acceptor.  Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
What are the official names of this protein?
Glucose 1-dehydrogenase, GDH, GlcDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
Protein: MUTS_NOSP7
Sequence: MTASHSETPSTKPDASTFISDHLQVDRSKLSQMYLHYVETKDKYPHAVLLYRVGDFFECYFQDAVKLAQELELVLTSKQAGEQGRVAMSGVPHHAWERYATLLVEKGYAVVICDQVEDASEAAGRLVRREVTRILTPGTLLEEGMLKSSRNNYLAAVVIAANHWGLAYADISTGEFLTTQGSDLEHLTQELMRLQPSEVLVPTNAPDLGSLLRPGETSPHLPECLPPSFCYSLRSQVPFSQGEARPRLLQKFKVRSLEGLGCDRFPLAVRAAGGLLEYLEDTQKENPVPLQRLRTYTVTDYLIVDSQTRRNLEITQTVRDGTFHGSLLWSLDRTSTAMGGRALRRWLLQPLLDIKGIRARQDTIQELMENTPLRQDLRQLLRQIYDLERLTGRAGSGTANARDLVALADSLSRLPELSHLVTESHSPFLKALQKVPSVLEELAQKLHAHLVESPPILIKEGGLIRPSVNPLLDERKATVEADQQWIANLEVDERAKTGISTLKVGFNKTFGYYISISRTKADQVPANYIRKQTLTNEERYITPDLKEREARILSARDDLNQLEYEIFTALREEVAQEAEVIRNLSRAVAAADVLCGLAELAVHQGYCRPEMLSGREINIVDGRHPVVEQSLPAGFFVPNSTQLGQESLVSSHLSLADNQEQITNTSLREAAPTTTLSTSDQGQMTNDNPDLIILTGPNASGKSCYLRQVGLIQLMAQIGSFVPARLAKLGICDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATSRSLVLLDEIGRGTATFDGLSIAWAVAEYIAVDIRARTIFATHYHELNELASIVPNVANYQVTVKELPDQIIFLHQVQPGGADKSYGIEAGRLAGLPAVVIQRAKQVMGQIEKHSKIAMGLQNLD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MDH_CAUVC
Sequence: MARAKIALIGAGMIGGTLAHIAAREELGDVILFDIAEGTPQGKALDIAEASAVFGKDVALKGANDYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKAVGEGIKAHAPNAFVICITNPLDAMVWALQQFSGLPKEKVIGMAGVLDSARFAYFLAEATGVSVEDIHAWTLGGHGDDMVPMVRHSTVGGLPLPELVKQGWLSQDKLDAIVERTRKGGGEIVALLKTGSAFYAPAESAIAMATSYLKDKKRVLPCATYLTGQYGLNDLYVGVPVVIGAGGAEKIVEFETNDDEKAMFAKSVESVKGLMEACKAIDSSLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: RT18B_MOUSE
Sequence: MAAPLRHTLLKLVPTLLRSSYVAQVPLQTLCTRGPPEEDAPSSLPVSPYESEPWKYLDSEEYHNRYGSRPVWADYRRNHKGGVPPQRTRKTCIRNNKVAGNPCPICRDHKLHVDFRNVKLLEQFVCAHTGIIFHAPYTGVCMKQHKKLTQAIQKARECGLLSYYVPQVEPRDADFGTVHGAVSVTPPAPTLLSGEPWYPWYSWQQPPERELSRLRRLYQGNLLEESGPPPESMPEMPTTPPAESSIEQPGSQSA
What are the official names of this protein?
28S ribosomal protein S18b, mitochondrial, MRP-S18-b, Mrps18-b, S18mt-b, 28S ribosomal protein S18-2, mitochondrial, MRP-S18-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYAH_ALBVE
Sequence: MSSSEVKANGWTAVPVSAKAIVDSLGKLGDVSSYSVEDIAFPAADKLVAEAQAFVKARLSPETYNHSMRVFYWGTVIARRLLPEQAKDLSPSTWALTCLLHDVGTAEAYFTSTRMSFDIYGGIKAMEVLKVLGSSTDQAEAVAEAIIRHEDVGVDGNITFLGQLIQLATLYDNVGAYDGIDDFGSWVDDTTRNSINTAFPRHGWCSWFACTVRKEESNKPWCHTTHIPQFDKQMEANTLMKPWE
What is the function of this protein?
Cyanamide hydratase involved in the detoxification and/or utilization of cyanamide, a toxic nitrile compound distributed widely in the environment.
What are the official names of this protein?
Cyanamide hydratase, Urea hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanamide dehydrase family.
Protein: PIWL1_HUMAN
Sequence: MTGRARARARGRARGQETAQLVGSTASQQPGYIQPRPQPPPAEGELFGRGRQRGTAGGTAKSQGLQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKAIMIEVDDRTEAYLRVLQQKVTADTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL
What is the function of this protein?
May be a negative developmental regulator (PubMed:12037681, PubMed:16287078).
What are the official names of this protein?
Piwi-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis. Also present in chromatoid body.
Protein: COAX_BACSU
Sequence: MLLVIDVGNTNTVLGVYHDGKLEYHWRIETSRHKTEDEFGMILRSLFDHSGLMFEQIDGIIISSVVPPIMFALERMCTKYFHIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHLYGNPLIVVDFGTATTYCYIDENKQYMGGAIAPGITISTEALYSRAAKLPRIEITRPDNIIGKNTVSAMQSGILFGYVGQVEGIVKRMKWQAKQEPKVIATGGLAPLIANESDCIDIVDPFLTLKGLELIYERNRVGSV
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.  Cannot utilize a phosphoryl donor other than ATP.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1_CROXC
Sequence: MSFTVTKTAPALITPSEPTPSGHILPLSFFDRLPFLRVFLVDMIMVYGRGDQPAKVIKEAVAKALVHYYPLAGRLTTDTDDGELSVACTGEGVWFVEATADCRMEDVNYLQVEPLMIPKEQMLPSHPEGVDPYTLPLMIQVTQFRCGGFAFATRANHAVFDGIGAGQIKVAIGEMARGLKHPTVKPVWCRDVIRKPIPSQISATEPHDTDLSPVSDIKFTNNQTNIECCSFDLSLDHINHLKDRFAKEVGKICSVFDVITAKLWQSRTRAIGLQPQTEVSLTFLLNIRQVVLHNELPPDGGYYGNCLVPLVNKAPSGQIANAPLFEIVRLIKEAKDDLLRKDSASLIGGMPPYKKPSYADLSIVDWRRLGLYEADFGWGGPMFLVPLNEHTVTSCSTYLFKSPVASKKDVCLVTYCIVKEHLEAFRAEMNDFT
What is the function of this protein?
Caffeoyltransferase involved in montbretin A (MbA) biosynthesis (PubMed:29967287).  Catalyzes the caffeoylation of myricetin 3-O-beta-D-glucosyl 1,2-alpha-L-rhamnoside (MRG) to produce myricetin 3-O-(6'-O-caffeoyl)-beta-D-glucosyl 1,2-alpha-L-rhamnoside (mini-MbA), a precursor of MbA (PubMed:29967287).  Mini-MbA and MbA are potent inhibitors of human pancreatic alpha-amylase and are being developed as drug candidates to treat type-2 diabetes (PubMed:29967287).  In vitro, is able to catalyze the caffeoylation of quercetin 3-O-sophoroside (QGG), although QGG may not be a physiological substrate in vivo (PubMed:29967287).  In vitro, can use coumaryl-CoA, feruloyl-CoA and acetyl-CoA, although these three acyl donors may not be physiological in vivo (PubMed:29967287).
What are the official names of this protein?
Myricetin 3-O-glucosyl 1,2-rhamnoside 6'-O-caffeoyltransferase AT1, Acyltransferase 1, CcAT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: NKD2L_DANRE
Sequence: MGKLHSKHACKRRENPEGDSFVVNGFIAKRAAEEDERYGNNLKDYKNEELKDGRLTLLHCPLQVVLPPEKAEGCESFLQYLSPDDGERDAQKVKKRISLQDLECNVSLAEDNRQEWVFTLYDFDNSGKVTKEDMSSLMHTIYDVVDASVKHSCNTKRRSLRVKLSVTPEPAARRRDATHTERETSHLSQVEPVRSEEHRSADRRQSTHIRGQTEAHEGNHYCVDENTERRNHYLDLAGIENYTSRFDSSSPDADQDPPSRSSHSQSRPHSQEPETHVYQRRSQLIEPCVAPDPRLRTGPQLIRSRSPKGSSRFPGVIPNVTKTSKCHGHHQPIPTGQDVYHLTQQNHTHAHTPSGLQHSHSRRIRSRAREQQALTPVKNTNATALVQRHEHHHHHEHHHHHHYHHYHQT
What is the function of this protein?
Cell autonomous antagonist of both the canonical and non-canonical Wnt signaling pathways.
What are the official names of this protein?
Protein naked cuticle homolog 2-like, Naked-2-like, Protein naked cuticle homolog 2-B, Naked-2B.
What is the protein family that this protein belongs to?
Belongs to the NKD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.