PharMolix/UniProtQA huggingface dataset:
Protein: EF2K_RAT
Sequence: MADEDLIFRLEGVDGGGSSGAGRHGDSDTDSDDDEGYFICPITDDHMSNQNVNSKGQGYYNNLLKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLAPFDLSPREQDAVNQSTKLLQSAKTILRGTEEKCGSPRIRTLSGSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRPESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE
What is the function of this protein?
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation.  Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive.  In turn, the rate of protein synthesis is reduced (By similarity).
What are the official names of this protein?
Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
Protein: ISPD_MENPI
Sequence: MASVKKLAGKVAIVTGGASGIGEVTARLFAERGARAVVIADMQPEKGGTVAESIGGRRCSYVHCDITDEQQVRSVVDWTAATYGGVDVMFCNAGTASATAQTVLDLDLAQFDRVMRVNARGTAACVKQAARKMVELGRGGAIICTASATVHHAGPNLTDYIMSKCGVLGLVRSASLQLGVHGIRVNSVSPTALATPLTATIGLRTAADVESFYGQVTSLKGVAITAEHVAEAVAFLASDEAAFVTGHDLAVDGGLQCLPFVAVAK
What is the function of this protein?
Involved in the biosynthesis of menthol and related monoterpenes in leaves.  Can use (-)-trans-carveol and, with a lower relative velocity, (-)-trans-isopiperitenol, (+)-neomenthol, (+)-neoisomenthol and (-)-cis-isopiperitenol as substrates, but not (-)-cis-carvenol, (-)-menthol, (+)-isomenthol, 7-hydroxy-limonene, (-)-isopiperitenone or (-)-carvone.
What are the official names of this protein?
(-)-isopiperitenol/(-)-carveol dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL18_CHLTR
Sequence: MESSLYKKTSGKARRALRVRKALKGCSLKPRLSVVKTNKHVYVQLIDDVEGKTLASISTLAKVAKTSGLTRKNQDNAKALGIKIAELGKGLQVDRVVFDRGAHKYHGVVAMVADGAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: XRRA1_HUMAN
Sequence: MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRESLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLKSFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDEFCQEPTASDSQG
What is the function of this protein?
May be involved in the response of cells to X-ray radiation.
What are the official names of this protein?
X-ray radiation resistance-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDC80_ENCCU
Sequence: MTRRFTMTPNSRNPVKTPVSGMKVAPFPRHSIATEEVRRRDMRVVREKGYRQQCVDGILRFLVENGYDGQVSQKILHNPSSKDFQSIFKFLYGFVDDFTFSSRFEDEVVNVMKNLKYPYCGEITKSQLSAITPHTWPVILSMCSWLVDLISHGTSLLQQEEERSVESCFFEYVCDGYMRFMEGDEDDTALEEEFERRVTEIYTGIFKEIDRKKEELRRIEEMISEARKMSEGREELDRKKRELTDDLNMLIASEKQLEGKKRKYLGAISRLSEEIVKVEEEIESLRAQEDGLRAQITKQRINPEDVKEMNAEKIELFKELERMKPEKESLMKVVGEQEREAQERAEEVEKLFFDLKGLRDEISLRIVKDGKGVPRVANEVSGEVFSGMSGVIVRLEEELNSKSDVLVTAEMNKSILEEARGEKESITSELNSRLGYYSDKLVMAGKLYLEKKEISENEQRKSKTEMELLENELLKLNLESNTSLLMSEQKLQKARIVLDRTLNSINYEREEINKMIFGFYNAAMDIHASIQSQVGDLRALLNK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NDC80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: GCSH_ECOBW
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: LPPE2_ARATH
Sequence: MAASSSSLLLLHKPTYNFHFAASSVPTYINSARFRISSSIFPLDRRRRRRIWSVSGFKSMADLVKTNARRDGEDRFQALEQEAFISNSSSELQNELVSDAGDGIEAIANRLSKWIVAALFGSVLLLRHDGAALWAVIGSVSNSVLSVALKRILNQERPVATLRSDPGMPSSHAQSISFISVFSVFSVMEWLGTNVLSLFLSGFILALGSYFTWLRVSQKLHTTSQVVVGAIVGSVYSTLWYVTWNSLVLEAFTSTFSVQIALFLVAAASALGFAVYVLLNWFKDDR
What is the function of this protein?
Exhibits phosphatidate phosphatase (PAP) activity in vitro.  May play a secondary role as PAP in plastids.
What are the official names of this protein?
Lipid phosphate phosphatase epsilon 2, chloroplastic, AtLPPE2, Phosphatidic acid phosphatase epsilon 2, Plastidic phosphatidic acid phosphatase epsilon 2.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: YEGS_PECAS
Sequence: MEKNPITLLILNGKSAGNDELREAIGELRKDGYTLHVRVTWEYGDAKRYVEEAIQLKADNVIAAGGDGTVNEVAAALAVQPEAVRPCLGIVPLGTANDFATSCQIPMEMHNALTLAIKGRATAIDIAKVNDGHYFINMATGGFATRITTETPAKMKAALGSASYVLHALFRMDMLQAERCEIHGPDFHWSGDTLVIAVGNGRQAGGGQQLCPEALINDGLLELSVLSATELLPNMLQAWFTGSENQNMISATLPWLEISAPDDMTFNLDGEPLTAKRFRIEVLPAAIHCRLPPQCSLLE
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_AERHH
Sequence: MAKTPTRARKRVKKQVSDGIAHVHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGEIAKEYGVKNLEVMVKGPGPGRESSIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FLGH_GLUOX
Sequence: MRHAFRHSVRTLGLLGLLPVLSACNSLAQMSEIGRPPRMTSITDPTLANSYRPVTMPMPPLQAPPDEAASLWRSGSKAFFKDQRASQVGDLVTIIVDITDNAAFNNGTTADRTADEKFGIPNLFGIKGKVISAITGADSLSTASSSDSGATGKITRNETVTLRLAGTITQVLPNGNFVVMGKQEVRVNSELRELGVSGIVRPQDITADNTVTHDRMAEARISYGGRGTLTQLQTPRYGQQVMDAILPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RT25_CANAL
Sequence: MKIQTDAANVLQRASAQLKSGLLKEKPLWYDIIAKYPPTSTNDLIKKSHVYEGKSDPRNNSIIYKYPNSNNKNNNVLFKTRPSNKELKSKNHNIHKLPKLKFIEDSLRKIFYQQHPWELSRPKNLIDNGNGNNNEKCDWSHMLQLHKPLDGESVVQRTLWLLKNNTTKGLTMVEAYDKARFEFYKLRMSEEMESHVAKEESTMYGSVFTSTTVNWNLSKEQEYINDWTIIAKERTQVIEANMNKSSAPIGSVVEEEKSQSSLFEDLLSNDNLQSEPEVEQSGQQQQQEQPKQETN
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL36_OENOB
Sequence: MKVRPSVKPMCDQCRVIKRNGRVMVICSANPKHKQRQGK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: P4R3B_XENLA
Sequence: MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVDRLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDVTQDPIDESEEERFEEMPETSNLIDLPTCELGKLEEIADLVTSVLSSPIRREKLALVLENEGYIKKLLQLFQTCENLDNTEGLHHLYEIIRGILFLNKAALFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDVILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLANLGILPALEIVMGMDDLQVRAAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDSDPELGGAVQLMGLLRTLIDPENMLATANKTEKSEFLNFFYNHCMHVLTAPLLANTAEDKLEKDAVLGSIKTSTVCPDNFQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLILMNSKHTFLALCALRFMRRIIGLKDEFYNRYIIKGNLFEPVIHALLDNGTRYNLLNSAIIELFEFIRVEDIKSLTSHIVENFYKALESIEYVQTFKGLKTRYEQEKDRQSQKLSSVPSILRSNRFRRDARALEDDEELWFNEDDEEEGEAVVPPVEKTKPEDDFPEGYEKFLETKKAKELEDKENLPKRTSVGGFKFTFSHSVSAANGANSTNSKSVAAHTPPATSNGSSSKNTSLTTTVASTKGSLIGLVDYPDDEDEEEEEDTSPRKRPRLGS
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 3-B, SMEK homolog 2-B.
What is the protein family that this protein belongs to?
Belongs to the SMEK family.
Protein: Y3544_CROS8
Sequence: MDALDAISKWLAKQHVVTYCVGNGEALWCANAFYLYDRERVAFYLLSDTESRHGKMAGKLAPVAGTVNGQTKTVALIRGVQFSGELRLVEEPESEALRERYNRRFPVARVMSSPLWEIRLDEIKFTDNTLGFGKKLVWLRAEQA
What are the official names of this protein?
UPF0306 protein ESA_03544.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: POTA_LACPL
Sequence: MAVNTQPIIRLTNVTKSYGEHQVLKNINLDLEAGKFYTLLGPSGCGKTTILRTIAGFTDATSGQVYFDGQVINTLPANQRQVNTVFQDYALFPHMNVAENVAFGLKLHKVPKDEIETRVQKALAMVQLADLGEREISEISGGQQQRVAIARALVMQPKVLLLDEPLSALDAKLRKDMQYELRDLQQRLGITFLFVTHDQEEALAMSDEIFVMNAGEILQGGSPVDIYDEPINHFVANFIGESNIIPGKMLKDFEVEFVGKQFECADAGMQPNEAVEVVLRPEDLDIVAANQGKLVVTVDSQLFRGNYFEIVAYDTDHNEWLVHSTNPAAEGEPIGLTFDPQDIHVMRLNESEAAFDARLEQYEDD
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPDA_STRZT
Sequence: MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_SHMV
Sequence: MSEVSKISTLLAPEKFVKLSVSDKFKWKAPSRVCSIVQSDTISMTANGRSLFTFDVLKDVLKHAEEYTYVDVLGVVLSGQWLLPKGTPGSAEIILLDSRLKGKASVLAVFNCRAATQEFQFLISPGYSLTCADALKKPFEISCNVIDLPVKDGFTPLSVEIACLVQFSNCVITRSLTMKLKENPATRTFSAEEVDELLGSMTTLRSIEGLRKKKEPNDVVQGHLSAEYDVKRSVKRTKSENTPGKRRVNVDSVSLGLGKGKSVSAKNEDTESVFDDGILDSDS
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma.
Protein: ATPB_BARJA
Sequence: MRINPTTSGSAVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVICEVQQLLGNNRVRAVAMSATDGLTRGMEVLDTGAALSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEGEKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SCX1_TITMA
Sequence: KKEGYLVGNDGCKYGCFTRPAQYCESECSLRKGTGGYCYAWLACYCYNMPDWVPTWNSAKNRCGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (PubMed:31402191).  This toxin acts on human Nav1. 4/SCN4A and Nav1. 6/SCN8A voltage-gated sodium channels (PubMed:31402191).
What are the official names of this protein?
Beta-mammal toxin Tma1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_STAEQ
Sequence: MSERNDRKVYVGRVVSDKMDKTVTVLVETYKTHKLYGKRVKYSKKYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL17_BORBU
Sequence: MKTKLGFNRLSRKSSHRRALLKNMVISFFKHEKISSTKTKLFEVKRFAERLITRAKVDTVHNRRELSKFIHDKHILNKLFTKISPVFRQRSGGYTRMIKLGKRYGDAAEMAILELVEKPLKVE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYE_THEVO
Sequence: MYEEEIKKIALLNAYQHNGKAELKSVIGKVMAEIADLRKNPKLVSELAKAAVDSVNSMSKDDIVNIVEKQFPEALKKDKKPEEHRLPDLQGVNGHVVMRLAPSPSGPLHIGHTRMAILNDEYVKRYGGDLILRIEDTNPTNIDPEAYAMIPEDLEWLGVNVTKTVIQSERFDLYYSVAKKLIENGHLYICTCDREEFKRKKLASIPCKDRDNPPETNLYLFEKMLDGEIKAGAAVAVMKTDLNHPNPSVRDWIAFRIIDAKHPRTGDKYRVFPMMSFSVAVDDHYLGLTHVLRGKDQLTNTEKQRYVFEYNGWNKPYYYHYGMIRFPGTRLKTSLMKKGIQAGQYDGWSDVRLGTVRAMARRGYQPETFRRYWINSGLREIDAVFSWEIFNSLNREFVDPKAYRFSFTKDPVEIKMEGSNGLTARLPYHPSHPEYGVRKYEIGDTVYISKGDADKIADGERFRLKDLCYVVRKGDRFLFDGTEMKEKTKIINWCPPNSREFQVLKPDGSIDKGLIEPASKGYRGISQLERYGYVNFYDSDEKAYFTHD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_SHESR
Sequence: MAKLHDKYQETVVAELTKKFGYTSVMQVPRIEKITLNMGVGEAVADKKVMEHAVRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTSANTDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: STHA_MYCTU
Sequence: MREYDIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTLREAVLYLTGMNQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLAVTFRFGEEVTAVDVGSAGTVTTLASGKQIPAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDRFQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYVGATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATEMVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAALDVMNKMRALNQFRR
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Probable soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRBP1_MOUSE
Sequence: MDELAFGEAALEQTLAEMCELDTAVLNDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASLASSLEAFLGGPKVTPAPLSPPPSAPAALKMYPSVSPFSPGPGIKEEPVPLTILQPAAPQPSPGTLLPPSFPAPPVQLSPAPVLGYSSLPSGFSGTLPGNTQQPPSSLPLAPAPGVLPTPALHTQVQSLASQQPLPASAAPRTNTVTSQVQQVPVVLQPHFIKADSLLLTAVKTDAGATVKTAGISTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLTLRSAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSPSQSSPLSFGSRASSSGGSDSEPDSPAFEDSQVKAQRLPSHSRGMLDRSRLALCVLAFLCLTCNPLASLFGWGILTPSDATGTHRSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFPQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGQAGGLLRDRGLRKDARASARDAAVVYHKLHQLHAMGKYTGGHLAASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPPESLYSVAGNPVDPLAQVTRLFREHLLERALNCIAQPSPGAADGDREFSDALGYLQLLNSCSDAAGAPACSFSVSSSMAATTGPDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQDTERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTPTGSSIDKAMQLLLCDLLLVARTSLWQRQQSPASVQVAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTTAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS
What is the function of this protein?
Predominant isoform expressed in most tissues, which has weaker transcriptional activity compared to isoform SREBP-1A (PubMed:12855691, PubMed:21531336).  Primarily controls expression of lipogenic gene (PubMed:8833906, PubMed:9062341).  Strongly activates global lipid synthesis in rapidly growing cells (PubMed:8833906, PubMed:9062341).
What are the official names of this protein?
Sterol regulatory element-binding protein 1, SREBP-1, Sterol regulatory element-binding transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the SREBP family.
What are the subcellular locations of this protein?
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum (PubMed:21459323). Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed (PubMed:21459323). SUBCELLULAR LOCATION: [Processed sterol regulatory element-binding protein 1]: Nucleus.
Protein: TRPB_SALHS
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ACP_POLSJ
Sequence: MSDIEARVKKIIAEQLGVEEGQVTSEKAFVADLGADSLDTVELVMALEDEFGIEIPDEDAEKITTVQNAIDYANTHQKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_PARP8
Sequence: MVPWLGPDDPFPPVERALSAASGAPGLLAASADLLPSRLIDAYRRGIFPWYSDGQPVLWWTPDPRMILRPREFKISPSLKKTLRRVLRDDTWEIRVDADFPAVMRACALAPRHGQRGTWITSDVIDAYSTLHRRGEAHSIETWHAGKRVGGLYGVSFGKMFFGESMYAEVTDASKIALSALVFHLRRHEIEMIDCQQNTSHLASLGGREIARKAFVAHVRAAVDSAPIPWSFDKSVLRDLLAPAQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.