PharMolix/UniProtQA huggingface dataset:
Protein: SRP68_DEBHA
Sequence: MSAYLSSSEDYHKQRKRLNKRLLKLRHELDLITPDTKDYKKKEKISKISSSDYDQDEKYGLLLLLTAERDSLYSSEIKSLLEISNDNASSYRNLMISRIKKSLSSSKKLLEITVNEKDEYKRIEYYTYAALIQGNLSVNKKQWSKALNAFSIAKCALDFLYSQEDSKMDIEEEQEESTQFKKTLISEITETLVDPSLALAISQDDTAYSTTTDLKTVSRQHCRDNKLSYLQPVIEIIARIDPEAVSEVSSSTELIKSVQWRDHEATLYNDELAYKIMKLTNDNETNWKNFNDANQFDVLLSGWSELLEIHTNDMDKNKDEDDLEKVQDRAIVLTYINFNLLFTRLKRDLLIIDQLSSQGDNVFALKKLEFNKDIIRLYGTIITTTQEIKDLPGVYNDEDLHESLDNLEKFFVAKKSAVLARSFALNNKFPEALKIFDHVDNTLSSSDNKFYKIDEFPYNVSSNVEFEKFKKELPSQVLQAQILAQFSVDLSKNLNQSNFVIENMNKYPVSNETLDNIANFNKNLSIAPVLSKPVLFDIGFNYINYGMGRSSSYNNSNSATSTTSDSTTDQNDPNKKKSGFFGIFGRS
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (By similarity).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity).  Binds the 7SL RNA, srp72 binds to this complex subsequently (By similarity).  The SRP complex possibly participates in the elongation arrest function (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP68, Signal recognition particle 68 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP68 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Endoplasmic reticulum.
Protein: ZACN_HUMAN
Sequence: MMALWSLLHLTFLGFSITLLLVHGQGFQGTAAIWPSLFNVNLSKKVQESIQIPNNGSAPLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQAHVVNEIVSVKREYVVYDLKTQVPPQQLVPCFQVTLRLKNTALKSIIALLVPAEALLLADVCGGLLPLRAIERIGYKVTLLLSYLVLHSSLVQALPSSSSCNPLLIYYFTILLLLLFLSTIETVLLAGLLARGNLGAKSGPSPAPRGEQREHGNPGPHPAEEPSRGVKGSQRSWPETADRIFFLVYVVGVLCTQFVFAGIWMWAACKSDAAPGEAAPHGRRPRL
What is the function of this protein?
Zinc-activated ligand-gated ion channel.
What are the official names of this protein?
Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYQ_BUCBP
Sequence: MKKQHSKISNFIQKIISEDIQNKKITHVKTRFPPEPNGYLHLGHAKSICLNFDLAQEFKGTCNLRFDDTNPKNEDTCYINSIIQDIKWLEYKWHNKIRYASLYFNKIYQYAIKLIKKGLAYVDQLSPEEIRTFRGTLTTSGIDSPYRTQSIEKNLNLFKKMKQGKMLEGTACLRAKIDMASNCITMRDPVLYRIIFSKHHQTNKKWCIYPTYDFTHCISDALEKITHSLCTLEFQDHRKLYEWILKKIDISCNTHQYEFSRLKLEYSVLSKRKLNLLVNNKVVNGWDDPRMPTLSGLRNRGYTPSSIKLFCKKIGITKQENTIQLSFLESCIRSDLNPIAPRYMAVIHPIKIQICNLSDNYEEILNIPNHPTKPNMGCHKSIFSNTLYIDQNDFYENKSELLKKLAIGKEIRLRYSYVIKAHKIKKDQNNNIKTIFCTYDKNTLGKNPKNRKILGVIHWISEKNVLPARFFLYDKLFTIQSPETVKNFLQYINTNSLVIKYGFVEKDILTNISTTAYQFEREGYFCINKNFSITKNLTFNRIVTLKDKIK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENCD_ASPFU
Sequence: MTKPQPPPILDFSVFYGHDSQAKAQLVQRVRECCLNNGFFQITGHKVSPELQRRTFDCAKRFFDLPLIEKKKIERSPDAFNRGYEAFQSHMSQPGSAPDRKEGLFLGPDLAEDHPYCVQKKLNCGPNRWPQGLDDLEEFKLVSMEYYAALFQLAKDVVAVLALTMDYEETFFDPLTEGAIATLRYLHYPPQPVGDAEAGLGTGAHRDYSCITLLLQDGTGGLQVLDEPTGQWLDVKPVPGAYIVNLANVFARMTNGHYKSALHRVVNKSGMERYSIPFFFTGNPDYVCECLSRFRKEGEPVRHPPATVHEVVAEAVRGTVERANRYNAERQGIHAAQ
What is the function of this protein?
2-oxoglutarate-Fe(II) type oxidoreductase; part of the gene cluster that mediates the biosynthesis of endocrocin, a simple anthraquinone interesting for many biotechnological applications (PubMed:22492455).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) encA (PubMed:22492455).  The atrochrysone carboxyl ACP thioesterase encB then breaks the thioester bond and releases the atrochrysone carboxylic acid from encA (PubMed:22492455).  The atrochrysone carboxylic acid is then converted to endocrocin anthrone which is further oxidized into endocrocin by encC (PubMed:22492455).  The exact function of encD has not been identified yet, but it negatively regulates endocrocin production, likely through the modification of endocrocin itself (PubMed:22492455).
What are the official names of this protein?
2-oxoglutarate-Fe(II) type oxidoreductase, Endocrocin synthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: SYG_TREDE
Sequence: MEDHKISMEKIVSLCKRRGFVFQSSEIYGGQNGAWDYGPLGIELKNNVSRAWWKEMTQLHDNIVGLDAAILMHPRTWEASGHVENFTDPLVDCKKCKSRFRADHLPPENLEKRVCPDCGGELTDTRKFNLMFKTHIGPTDDNSSVIYLRPETAQGIYVNYKNIIQSNRMKIPFGIAQIGKAFRNEIVTKNFIFRTCEFEQMEMQFFVKPGTDDEWFDYWKKQRWAFYEKYGVRTNKLQWHQHGKDELAHYAKDAYDIEYEFPMGFKELEGVHNRTNYDLTRHTEYSGKDMQYIDQDNGNEKYIPYIIETSAGLTRNVLMFICDAYDEEKVADKGNDDDWRTVLRFHPNIAPITVAVLPLMKKDGLAELAEEIRNELKEEFKTDYDQSGAIGKRYRRQDEVGTPFCVTVDYDSKEDNTVTLRFRDSMEQVRIPRTELISRIKTEIKNYKRAH
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_SHEB2
Sequence: MSQSAVSFQISPVSKTQDPLIQQKIDLKTKPPGALGQLESLALQIARVQATDSQQTDQPQNTVLKIVHPTMLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFTLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQAGCNLVAFGEMGIGNTSAAAAIMAAIMQLDVIDCVGRGTGINSETLERKLMLIELALLLHQSALTGPKSVLACLGGFEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVQIAPNVRDYLIFAHQSDEQGHQRMLEFLQAKPLLSLGLRLGEGTGAALALPLIQASVNFYNQMASFSDAGIEAVV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: NU2C1_IPOPU
Sequence: MSWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKERPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDFITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGAFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVFIGLLTSVVSIYYYLKIIKLLMTGRNQAITPHVRNYRRSPSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YQGF_COXBN
Sequence: MPNQNLIALGFDFGMKRIGVAVGQTVTHSANAIAILKAQDGVPDWEKIKMLIETWHANVLVVGIPYNMDGSEQTLTFAARKFARKLQTRFGLPVSMVDERLTTIEAKRQWYEQGLTKRPQHLDNYAAKLILEQWLQEQKNE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STRPC
Sequence: MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYACDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIRNYDYKVLMQFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_BUCAT
Sequence: MNFPCIYHVYSIRKIMFLVIVACLPGIFAKYYFFGIGTLIQIFFSIFISLVLEIIILKIRSKNIKNYLQDTSLVLTSVLFGVSIPPLLPWWMTSIGLFFAIVVAKHLYGGIGQNIFNPAMVGYAVLLISFPVYMNNWNERDFSLSFFNDFKKSAYIIFFKNDITTVSSSYLNIIPDAFTTATPLNNFKIKSHLKDDFFLKENIIKNKEVSIQTSWKCINISFFLGGIFLLFTKIICWRIPISFLSSLGMLSIITYFYSKELFMSPQVHFFSGGTMICAFFIATDPVTAACNNVGKIVFGIIIGFLVWIIRNYSDYPDAIAFSVLFANMTVPLVDYYTKSSGYGRNNI
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_DYMPI
Sequence: MTNLRKTHPLMKIINNSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFVIAALAGVHLLFLHETGSNNPSGLTSDSDKIPFHPYYTIKDILGALILILVLTSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLALMPLLHTSKQRSMMFRPISQCLFWLLVADLFTLTWIGGQPVEHPFIIIGQLASILYFMLILVLMPIASLAENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y473_GEOTN
Sequence: MPAYPREGKIIQIHSYKHNGTIHRIWQETVVLKGTSAYVIGGNDKTLVMEADGRTWVTREPAICFFHAKHWFNIIAMIREDGVYYYCNLSSPFVWDDEALKYIDYDLDIKVFPDMTYMLLDEDEYERHRREMNYPDVIDRILKNNVQKLIGWIQERKGPFAPEFIDKWYGVFQAYQK
What are the official names of this protein?
UPF0374 protein GTNG_0473.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: PURA_ECOL6
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3605_BACCZ
Sequence: MLEKTTRMNYLFDFYQSLLTQKQRSYMSLYYLDDLSLGEIAEEFDVSRQAVYDNIKRTEAMLEEYEEKLVLLQKFQERQRLVAKLKQLISEEEHVNEEMKQVVEAIEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BCE33L3605.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: ARNB_ECOLU
Sequence: MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARLLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIALQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVNEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTMSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: PSAI_MAIZE
Sequence: MTDFNLPSIFVPLVGLVFPAIAMTSLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PCKG_MYCBO
Sequence: MTSATIPGLDTAPTNHQGLLSWVEEVAELTQPDRVVFTDGSEEEFQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNWMDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMTRMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCTPMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTAAAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDGRFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALAVDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIAA_SHIBS
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: ACPS_SALPB
Sequence: MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWDIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALILAEKLGVAHMHVTLADERHYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ACIAC
Sequence: MTHPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPIDFSGVRGKGLATLALLPLRLLRAFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPLVVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNPLRTAFTRQADPQARFAGRGGPLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATLTPFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAGGGWLVQQRDLSAEALAQLLQNTEREALLERALKAKTMQKIHATREVANACEELTA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EHF_PANTR
Sequence: MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIVNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
What is the function of this protein?
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation.  May act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades.  Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.  Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter (By similarity).
What are the official names of this protein?
ETS homologous factor, ETS domain-containing transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSGA_CLOK5
Sequence: MRGTIMKGIGGFYYVNTDRGIIECRARGKFRYNGLFPMVGDKVEIKLERDQGIIDEICPRISQLKRPAVANVTQALVVFAFNHPEINEDLLNKFLISCEFNNLKPIVCFNKLDLADKEKKLDVIDMIRNTGYEVIFLKAKEGYGIDKVREKLKDNITVLCGPSGVGKSTILNAIYGKELMETGQISHKLNRGKHTTRHSEIIELEDGFMVDTPGFSSLDIGHITKDKLQYCFPEFIEFIGICKFTGCVHHKEPDCAVKSALYDDKINKRRYDFYVKTLNEISSKKKY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRX2_BOVIN
Sequence: MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISSTEFLQVIEIHNHQPCSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVIHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNRRYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGADFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQRKNEKEQERRLQQAMVSRQMPSESVDPTFSPRMPYPGFTAEGRSTLGDTEASDPPPPYSDLHPNNQESTLSHSRMESSVFMPRPQAVGSSSYASTSAGLKYPGSGADAPPSHRAAGDSAEESDDSDYENLIDPTEPPNSEYSRSRDSRPMTHPDGGSQI
What is the function of this protein?
Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates.  May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (By similarity).  Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (By similarity).  Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression.  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.  Required for normal induction of p53/TP53 in response to DNA damage.  Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (By similarity).
What are the official names of this protein?
BRISC complex subunit Abraxas 2, Abraxas brother protein 1, Protein FAM175B.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abro1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=A minor proportion is detected in the nucleus. Translocates into the nucleus in response to DNA damage. Directly binds to microtubules and is detected at the minus end of K- fibers. Co-localizes with NUMA1 at mitotic spindle poles.
Protein: SYH_CHLPB
Sequence: MSEYRAVKGTKDIFPDEITSWKYIEGVIHRVVGLYGFQEIRTPVFEYTDLFQRSIGSTTDIVGKEMFSFRPEPDGRSVTLRPEMTAGVMRAFLQANLSSASPVHKLYYIAELFRKERPQAGRQRQFSQFGAEMLGASSPEAVAEVIDMMMQVFTSLGVSGLRLRINTLGDLDDRVRYRDALRAYLEPHSGLLDAPSRERLEKNPLRILDSKNPDIQSVIADAPKLHDFLNPSARAEFDQVLLYLDQKSIEYVIDPLLVRGLDYYCHTAFEVVSPELGAQDAIGGGGRYDGLARELGSKSDIPAVGFAVGMERLLITMEKQGLLRHIVPSGPRVYIVLQNEELKTHALSACDLLRRSGIRTEMDLCGRSMKAQMREANRQHADYALFVGKSEVESQAYGLKNLRTSEQDFLSIREMIARLASSTKHVEVPDGGPD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.