PharMolix/UniProtQA huggingface dataset:
Protein: LLDD_ECO81
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTILLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUAC_YERPS
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: PUR5_ANAD2
Sequence: MSLTYRDAGVDIDEGDRLVDLIKPHARPTLRPEVLGGIGGFGGLFALDVKKYREPVLVSGTDGVGTKLKVAFAADRHDTVGIDLVAMCVNDIAVVGAEPLFFLDYYATGKLSAEQGAQVVKGIAEGCRQAGCALIGGETAELPGFYERGEYDLAGFAVGCVDRPRIVDGTRVARGDVVIGIASSGLHSNGFSLARKALLERYPLDHRFDALGGRTLADALLEPTRIYAKDVLALLEQVPVRAFAHITGGGLPGNVPRTLPDGTRAVLEEQRWPRPAIFDLVEREGQVPRDEMYRTFNMGLGLVAVVAPGDEAAAHAALRARGLEAWTVGAIEAGGPGEATCEVVR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGH_STAAN
Sequence: MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDEARFVIK
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPB_BIGNA
Sequence: MTTNTGKVTQIIGPVIDITFPIEAMSSVNIYDAVVIEDKTEKLSVTCEIQQLIGSQSVRTVSMSSTDRIKRGMDVVQTGTAIAVPVGKSTLRRIFNVLGQPIDNLGDVKNEETRPIHRSAPEFVDLDIRLEIFETGIKVIDLLAPYRRGGKVGLFGGAGVGKTVLIMELINNIAKAHGGVSVFAGVGERTREGNDLYAEMKESGVIVEDNLLESKVTLVYGQMNEPPGARMRVGLAALTMAEFFRDSSKQDVLLFIDNVFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGGLQERITSTKDGSITSIQAVYVPADDLTDPAAATTFAHLDATTVLSRGLASKGIYPAVDPLGSTSTMLQPWIVGDSHYECAQKVKQTLQRYKELQDIIAILGLEELSEEDRLTVDRARKIERFLSQPFFVAEIFTGLAGKYVGLNETIFGFNKILSGDLDSYNEQAFYLVGNLTDAEGKMKTISEN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y3328_SALAI
Sequence: MPSGSDLSDTDTTLVVVTGVSGGGRSTVARALENVGYYVVDNLPQALMLDMAELAMKAGGAARRTAMVLDVRSRAFSTDLVGAIRELKERGFAPWVVFVDADDEVLIRRFESVRRSHPLQGEGRLADGIAVERGLLEGARDQADVIVDTSHLNVNQLRRRIEELFGAEDARRLRVTVVSFGFKYGVPPDADFVCDARFLPNPYWVPELREHTGQTEAVSSYVLGQEGAEAFVATYTDLINATTAGFEREGKRYLTVAVGCTGGKHRSVAIAEELAARLGRTVIAANTQHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Sare_3328.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MTBR_BACIU
Sequence: MTLKIDIKGRGKYKPASDYSIDDVKNVLMEKIFEESSRIINSDDDLEIIEKVDFRTDKINVLSLFSGCGGLDLGFELAGLAAVIGEQAAMEAFKDKDRFNELRNKSIFHTIYTNDLFKEANQTYKTNFPGHVIQHEKDIRQVKYFPKCNLILGGFPCPGFSEAGPRLIDDDRNFLYLHFIRSLIQAQPEIFVAENVKGMMTLGKGEVLNQIIEDFASAGYRVQFKLLNARDYGVPQLRERVIIEGVRKDISFNYKYPSPTHGEETGLKPFKTLRDSIGDLVTDPGPYFTGSYSSIYMSRNRKKSWDEQSFTIQASGRQAPLHPGGLSMKKIGKDKWVFPDGEENHRRLSVKEIARVQTFPDWFQFSQGTNSQTSINNRLDKQYKQIGNAVPVLLAKAVASPIANWAINYLESSPNNKIKNRERKLSIRTFLRIKTS
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GGCC-3', methylates C-3 on both strands, and protects the DNA from cleavage by the BsuRI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BsuRI, M.BsuRI, Cytosine-specific methyltransferase BsuRI, Modification methylase BsuRI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: RS14Z_HELPY
Sequence: MAKKSMIAKAQRKPKFQVRAYTRCRICGRPHSVYRDFGLCRVCLRKMGSEGLIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: OXYR_ECOL6
Sequence: MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVGPYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPLFDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTHFRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGSPLRSRYEQLAEAIRARMDGHFDKVLKQAV
What is the function of this protein?
Hydrogen peroxide sensor.  Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA.  OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence.  OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR.  Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto-aggregation ability (By similarity).
What are the official names of this protein?
Hydrogen peroxide-inducible genes activator, Morphology and auto-aggregation control protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: TX306_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVRTCQQPKHLKYMEKAADKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1u, Toxin-like structure LSTX-B6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IAA24_ORYSJ
Sequence: MASSSSLRSTSCLASAAETDADNLCLRLGPPGSSITTTTTTGGADPAAKRSLGAKRSLESTDSMASGTGTSAAGDEHDDDTAAPAKAQVVGWPPVRAYRRNTFHQAAAAAAATKKGGDEKQKQQQQGGGLYVKVSMDGAPYLRKVDLKMCKGYRELREALDLLFTKCFSATASDGCSDGQFAIAYEDKDGDLMLVGDVPWEMFISSCKKLRIMKGSEAR
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA24, Indoleacetic acid-induced protein 24.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHG26_XENLA
Sequence: MGLPPLEFSDCYLDSPQFRERLKSHETELDKTNKFIKELIKDGKSLVAAHKSLSFAKRKFAGSLNEFKFRCIGDAETDDEICIARSLQEFAAVLGNLEDERIRMIDNAGEVLITPLEKFRKEQISAAKEVKKKYDKETEKYCGMLEKHMNLSSKKKEVLLHEADVQLDQMRQHFYEVSLEYVLKVHEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFSDFKTQLSISIQNTRDRFEGTRSEVESLMKKMKENPHEHLALSPFTMEGYLYVQEKRHFGTSWVKHYCTYQRETKQMTMVPFDQKSGGKVGEEELVQLKSCIRRKTESIEKRFCFDVEGVDRPTVLTMQALSEEDRKLWMEAMDGREPVYNSNKDSQSEGTAQLDNIGFSIIRKCIQAIETRGINEQGLYRIVGVNSRVQKLLNILMDPKISPETETEIPSEWEIKTITSSLKTYLRMLPGPLMTYQFQRSFIKAAKQESQESRIKEIHCLIHRLPEKNRQMLHLLMTHLANVAAHHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVVEIIIENYEEMFSTVPEMPQTNSQLHLSRKRSTDSKPPSCSERPLTLFHTSHSSEKEEKRNSVNSSAESVSSSNANSSVNSTCTQRSNMNNLNASDPDLDVAKVSRPNSLLNPKNISGLLPSSLNPSPTSPPTCPMVSAPSSPMPTSSTSSDSSPVSVPRKAKALYACKAEHDSELSFSAGTVFENVCPSQEPGWLEGTLNGKTGLIPENYVEFL
What is the function of this protein?
GTPase-activating protein for rhoa and cdc42.
What are the official names of this protein?
Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=Colocalizes with actin stress fibers and cortical actin structures.
Protein: LMLN_CAEEL
Sequence: MKPRLIFIFFACYFLNFLPFSNQLPCSYQNPRIEDILLEVPIEHEHPHRHRRGLPSSDPTSPPVEKFAPLRIQLHYDKSIQNLTAEVQNFVNTTLLPEAVGYWENALRVRPMTTPIRLRRKCISSFYYYKQGMRNVACDKGCRERTTCGEADIPRDHLLDCLACNNTDDCKTTGELGEGVKDTDFILYVTAHDSKRCEGPETLSYAAHCQQEADFDRPIAGNVNLCPSALSVHNHDYEILTSTVKHEILHALGFSVGLYAFFRDSEGKPRTKRNRYGRPTSLNKQKGYYDWDSNTITTVLRENWWTGEGKVIHPIHMMVTPKVREEARRHFGCDKLEGAELENQGGEGTYLTHWEKRAYENEAMTGTHTQNPVYSRLTLAFLEDTGWYQPNYEVAEDLHWGKQLGCDFAMKSCGEWIHEKKILGEDAYPYCSDIKHDGSKSMAITRCTTQRDSLALCNLVPFQKELPSQYRNFMSLPGVNPDGAKYYGGSVEMADYCPFLQEFEWKLIDKTQHKDSRCELEGNGKEGEDILEVYGANSKCFEFPKPWTERKCGRIRVLSHYMAGCYEHQCTNGTLYVGSYNATDMYPCYAENQKIHIKKVVDGWLREGSLICPKCEDYCTNCGPPIVIPDYIGDPELDEPCSSNFKLSVLAFLCYLIFLHIRS
What is the function of this protein?
Essential for the coordination of mitotic progression, and also plays a role in cell migration.
What are the official names of this protein?
Leishmanolysin-like peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M8 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in ring-like structures resembling invadopodia. In migrating cells it relocalizes from internal structures to the leading edge of cells (By similarity).
Protein: YG3W_YEAST
Sequence: MKHNRPNGTGKAVSGFKQIIRRLLLLLNKKRRKQLVIILKRITQVYGINLVFYVKKWKLKKLQGENIQINDIMPWLRESTILVLLNILYPTLMKFPFLKNHYIHWSSIVGISLMLTKGEVPSWIIAHFLVEAIASKLKIAKLTQWLKKKNFSQGTLIKFQQILVCLAIIVLFAKLDRSSLPFRVLFDHRPFLIDFFTINAIFTVLAVYHRTLKFFFTSGTKSNKNVGGHEVRNFSQYLGVKNHNDWPISSSNLKHVMDRLNEIHEVTIDDNYANINEKIINSYFTKGFFPSLKWTILRQCIEYLFVTKRRRLMGNKLRCIVMLLTFTFVDPTSKMKISPFFAKFFAKSLVNVYLKKYWHCNFGKYILFFLFQLSIM
What are the official names of this protein?
Uncharacterized protein YGR168C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RFCS_THEPD
Sequence: MSEELWVEKYRPRSLDEIVDQEEIVKRLKEFVKNKNMPHLLFAGPPGTGKTTAALALAHDLYGESWRDNTLELNASDERGIDVIRSRIKDYARTLPIGDVPFKLVILDEADNMTGDAQQALRRTMELFSRNTRFILIANYASKIIEPIQSRCAVFRFQPLPKGDAFQRLRWIAQQEGITVDDGALEAIWEESQGDLRKAINTLQAASAISRNVTEEVVYAALGRVKPKEVREMIESALKGNLLEARDKLRLLLYNYGLSGVDIIRFIHREVLSQKSVRLDDATLAELLVLVGETNYRIVEGSDDEIQLMALLSKLALVSKKAAKG
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: MNME_STAAN
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ACET2
Sequence: MRFTKMHGLGNDYIYVNCFEETVENPSEVAKKVSDRHFGIGSDGLVLIMPSERADFKMRMFNSDGSEAEMCGNAIRCVGKYVFDRGMTNKNVIRVETLAGIKVLELTVQDGKAKLVKVDMGEPILKPENIPVNSDKEIFRTEPVEIDGKEFKVTCVSMGNPHAVSYVKNVDIFPLEKIGPKMEHHPLFPKRINAEFVEVIDRTTLKMRVWERGAGETLACGTGACAVLVASVLNGVSERKATVKLLGGDLIIEWNENNNHVYMTGPAVKVFEGEVDLNEL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG30_PICPA
Sequence: MFSRKQVQKRNNELSSLHCSNSSNSLNRIHKNEETAKGTVGVNARGNNRSDNVASPGQLRPRTSSILTDNSEWILFSPENAEGEYVITSSDGIRRTNSNHYYYNYNEDDILSSSRRSSEDVYDAEQEYTEQPVNNHVQVEDEEDDDSIINDLTHVVDDYDYEEEDDKQDLTTRIDNWRKKQVSELLNELNHDDDLDPVLNRDKIDLIQSWGIENEKLNTKPRAKKRQRKSKRASFYGQDLLSKYSMEDLKIIKQIVAQLRDDLDKVKHDKPSSPLPNYHNTLKQAPSSNSQNPSFISYYSNYLTKNNSQQTPNSQSTSGSLLNNPNLEKYLPLFLKNLLYEDSNGSHQHPETSEKEHFWDNDLKSVNSSILTLSSNSKLKQEIL
What is the function of this protein?
Acts as the peroxisome receptor for pexophagy.  Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways.  Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole.
What are the official names of this protein?
Autophagy-related protein 30.
What are the subcellular locations of this protein?
Vacuole lumen. Preautophagosomal structure. Peroxisome membrane; Peripheral membrane protein. Note=Surrounds the peroxisome cluster, but a small amount is also inside the vacuole in methanol-grown cells. Upon induction of micropexophagy, localizes inside the vacuolar lumen. Also localizes near peroxisomes during early stages of micropexophagy.
Protein: WHIA_HALOH
Sequence: MSFTDQVKHEVSRLESNNKMCQLAELSALIMMNGSIQIINKNLAVKVRLYHGDLARKVYKLIKERFELNIEIMVRRRNHFSTYQNIYDLFLPPQPGIEVFLKKVGVLDEDHNLLFRIKKELVTSKSCQKSYVRGAFLGGGSVNNPRGEYHLEFRCEHESFAEDLLMLLKRFGLEGHLTEHRKKYVVYFKSFSEVATILNIIGAHKALLKLEDNKVLKEVKNGVNRRVNCETANLDKTVKAAMLQLEDIELIEKTRGLETLSNSLQEIAIIRKKYPYASLKELGKLLDPPLSKSGVNHRLRRIKSIANEIRGER
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RNAS1_ALCAA
Sequence: KESAAAKFERQHMDPSASSISSSNYCNQMMQSRNLTQDRCKPVNTFVHESLADVQAVCFQKNVACKNGQSNCYQSNSAMHITDCRESGNSDYPNCVYKTTQAEKHIIVACEGNPYVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_PARDP
Sequence: MATKSDPNYKIIAENRRARFDYFIESDLEVGIVLTGSEVKSLRTGQSNIAESYASVENGELWLINAYIAAYKQAGVFGHEERRRRKLLVSRKELARLWQAIGREGMTLVPLVMYFNDRGKVKLKIGVAKGKKVADKRETAAKRDWNRQKQRLLKQG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FRMD3_MOUSE
Sequence: MFASCHCAPRGRRTMKMIHFRSSSIKSLNQEMKCTIRLLDDSEVSCHIQRETKGQFLIEYICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAEFGDYYPDEHPENYISEFEIFPKQSQKLERKIMEIHNNELRGQSPAIAEFNLLLKAHTLETYGVDPHPCKDSRGATAFLGFTAAGFVVFQGNKRIHLRKWSDVCKLKFEGKTFYVIGSQKEKNAVLAFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTVSSSKIFFKGSRFRYSGKVAKEVVEASSKIQRDPPEVHRVNITQSRSFHSLNKQLIINMEPLQPLLPSPTEQEEEVPVGEGVPLPKMDVSEPLIASSPVKGAQCADPPDEEEDRVKEDPLTISELAYNPSASLLPTPVDDDEINMLFDCPSRLELEREDTDSFEELEADENAFLIAEEEELKEARQALSWSYSILTGHIWVNPLVKSFSRLLVVGLGLLLFVFPLLLLLLESGIDLSFLCEIRQTPEFEQFHYEYYCPLKEWVAGKVNIVLYMLGCS
What is the function of this protein?
Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.
What are the official names of this protein?
FERM domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FLS_CITUN
Sequence: MEVERVQAIASLSHSNGTIPAEFIRPEKEQPASTTYHGPAPEIPTIDLDDPVQDRLVRSIAEASREWGIFQVTNHGIPSDLICKLQAVGKEFFELPQEEKEVYSRPADAKDVQGYGTKLQKEVEGKKSWVDHLFHRVWPPSSINYRFWPKNPPSYRAVNEEYAKYMREVVDKLFTYLSLGLGVEGGVLKEAAGGDDIEYMLKINYYPPCPRPDLALGVVAHTDLSALTVLVPNEVPGLQVFKDDRWIDAKYIPNALVIHIGDQIEILSNGKYKAVLHRTTVNKDKTRMSWPVFLEPPADTVVGPLPQLVDDENPPKYKAKKFKDYSYCKLNKLPQ
What is the function of this protein?
Catalyzes the formation of flavonols from dihydroflavonols.  It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin (By similarity).
What are the official names of this protein?
Flavonol synthase/flavanone 3-hydroxylase, CitFLS, FLS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_MAGSA
Sequence: MIFSSIAFVAAETEAAKAALARLEQRYPHVDPGEADVIIALGGDGFMLETLHRFVDRRVPIYGMNRGSVGFLMNVYREHGLIERLSKAEEVILHPLRMKARTASGEEVEALAINEVSLLRETRQAAKLRIRIDGKIRMDELICDGILLSTPAGSTAYNLSAHGPIIPLGAGIAALTPISAFRPRRWRGALLPHTAKVVFEILEAGKRPVSAVADYTEARDVVEVEVREDRTCDLVMLFDPEHNLEERIITEQFLP
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PABP2_DROPS
Sequence: MADEDISLNEDQLLESMEETNGEQETEIVTETEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTGLAAVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNRFARGSFRGRGARASRACCHSTFRGARRAIRGYRGRANYYAPY
What is the function of this protein?
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product.  Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length.  Increases the affinity of poly(A) polymerase for RNA.  Binds to poly(A) and to poly(G) with high affinity.  May protect the poly(A) tail from degradation (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus.
Protein: RL35_DEHMB
Sequence: MPKMKTRKTAAKRFHVTGTGKIMRSKGMKSHLRRNKSARVLRQFDEMSQVAGVDRARIQKLIPYGVS
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CR11_RANSP
Sequence: GLLSVLGSVAKHVLPHVVPVIAEHL
What is the function of this protein?
Is inactive.
What are the official names of this protein?
Caerin-1.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZC21C_RAT
Sequence: MAGLQLAPHLPVGVMFPHNKTEAHGLHSAKHDPYEQSDSPQRSSMGHLRTSFQQKLWSNTELEQEDVISTHPKRNICTKARRHSCPHSAGISQQGSGNNAQGQGKGLFYLSSPTPRYPKANDQDFIPFRKKRVGVDRAYPLKPMVHRKSHSTSETGIDGDQNGYPRLPDSSEFSDSSFGLRSWVNPSLLASPQAEKVMAQLHRTEWTQIQRLEAAGESLQKEIRRKEILLREKLKKTEEGLRRIQREKKQAIFQEDRELQRMVLPRRRVRDGDLDTTHNSCLSPELRSEVFSRNRGEDQTCEQAQENSSPLQLSDYEIQRLKRERLMVSNNKIRDRDSGPSAGTFSQPAEDLGDELQASSLSGTPGSSGSSSSTEEQELGKCSHCGRSFLSLRLQRHSTVCGKMQGSKRKVFDSSRARAKGTELEQYLNWRGPATDKAEPPPRKSTWRQKHESFIRTLRHARQVQQVIARGGNPSDLPSILPAENPDYVQCPHCSRHFAPKVAERHIPKCKTIKNRPPPPRRHDS
What are the official names of this protein?
Zinc finger C2HC domain-containing protein 1C.
What is the protein family that this protein belongs to?
Belongs to the ZC2HC1 family.
Protein: ZAPD_PARP8
Sequence: MILYEYPFNERIRTLLRLEDLFERFTFFLTQEDAREHHVALTTLFEIAEVAGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEMEQTLAGLTQMQGKTGQHLADNEWLASIRSRAIIPGGTCKFDLPSYYAWQQTHPDQRRQDIAKWIMPLLPLRDAAAIVLRLARESGQASKVMAMQGSYQQMLSGRTYQLMQVRVAPELRVIPEASANKYMLWVRFTVQDGDLRPRAVDVDVPFQLTLCSL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RS20_BACC1
Sequence: MANIKSAIKRAKLSEERRAHNASIKSDMRSAVKTVEALVTNNDLENAKEAFKTASKKLDKAARKGLIHQNAAARQKSRLAKQVNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.