PharMolix/UniProtQA huggingface dataset:
Protein: KCNA2_ONCMY
Sequence: MTVATGDPSDEAAAHPGNPAEYDPDADHECCERVVINISGLRFETQLKTLSQFPDTLLGDPKKRMRYFDPLRNEYFFDRSRTSFDAILYFYQSGGRLRRPANVTLDIFSEEIRFYELGDEAIELFREDEGFVKEEERPLPDNEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRNDDDEPHSVFDTNTNTTIYFTSTYFTDPFFILETLCIIWFSFEFLVRLFACPSKSGFFGNVMNIIDVVAIIPYFITLATELAEKPEDGQAGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFESIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQCLGPVTKEDSNEELKKSRSGSTISKSDYMEIQEGVNNTIEDIPEENLKTQANCTTLANTNYVNITKMLTDV
What is the function of this protein?
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and central nervous system.  Prevents aberrant action potential firing and regulates neuronal output.  Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient.  The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity).  Can form functional homotetrameric channels and heterotetrameric channels with other family members; the channels characteristics depend critically on the types of channel-forming alpha subunits that are present (By similarity).  Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits (By similarity).  In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member.  Homotetrameric KCNA2 forms a delayed-rectifier potassium channel that opens in response to membrane depolarization, followed by slow spontaneous channel closure (By similarity).  Regulates neuronal excitability and plays a role as pacemaker in the regulation of neuronal action potentials (By similarity).  KCNA2-containing channels play a presynaptic role and prevent hyperexcitability and aberrant action potential firing (By similarity).  Response to toxins that are selective for KCNA2-containing potassium channels suggests that in Purkinje cells, dendritic subthreshold KCNA2-containing potassium channels prevent random spontaneous calcium spikes, suppressing dendritic hyperexcitability without hindering the generation of somatic action potentials, and thereby play an important role in motor coordination (By similarity).  Plays a role in the induction of long-term potentiation of neuron excitability in the CA3 layer of the hippocampus (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 2, Shaker-related potassium channel tsha1, Trout shaker 1, Voltage-gated potassium channel subunit Kv1.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDK3_CONCE
Sequence: MPKLAVVLLVLLILPLSYFDAAGGQAVQGDRRGNGLARYLQRGDREVQECQVDTPGSSWGKCCMTRMCGTMCCSRSVCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-D-conopeptides act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7 (IC(50)=0. 25 nM), alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=2. 8 nM), and alpha-4-beta-2/CHRNA4-CHRNB2 (IC(50)=28. 6 nM) subtypes.  Has no effect on alpha-3-beta-4/CHRNA3-CHRNB4, alpha-4-beta-4/CHRNA4-CHRNB4 and alpha-1-beta-1-epsilon-delta/CHRNA1-CHRNB1-CHRNE-CHRND subtypes of nAChRs.
What are the official names of this protein?
Alpha-conotoxin Cp20.3, Conopeptide alpha-D-Cp.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PETC_NITEU
Sequence: MRMIKFLLLAILLAPFVAHSSGQEVKLDKAPIDRADKESLQRGAKGFVEYCLTCHGANFMRFNRHHDIGMSEDDIRADLIHTGQKTGDLMEAAMRKKEAEGWFGVVPPDLSVIARARGADWLYTYLRTFYQDTSTYSGWNNLIFDKVAMPHVLHHLQGWQVLEPGTGNLVQTKPGTMTKEEYDRFVADLVNYMVYLGEPHAPYRRELGITVLLFLFGMLGLTYLLKKEYWRDIH
What is the function of this protein?
Part of the ammonia monooxygenase complex, which catalyzes the oxidation of ammonia to hydroxylamine, the first reaction in the process of ammonia oxidation to nitrite.
What are the official names of this protein?
Ammonia monooxygenase gamma subunit, AMO, Cytochrome c1, Heterotrimeric Cu-heme enzyme.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm. Note=Ammonia monooxygenase is active and distributed approximately equally in both subcellular fractions.
Protein: PANC_LEPBP
Sequence: MIVVSEIADLKTIISEWKQNQETIGFCPTMGTLHDGHMDLVKTSKGQCTKTIVSIFINPTQFNDPKDFDAYPKNTESDLKLCEEHGVDLVFLPSVEVIYPKSQTPIQMSIPSLQTTLCGRTRPGHFEGVLQIVSKLFHLTEPNYGFFGLKDYQQYRIISAMVEELNFPIKILGVPTKRESDGLAMSSRNLRLSPKDRETASLIPRMFQLAKKTLLGGEKNLIVWKEILTDFLLTGSNVKIDYLEIVDPITLQPLSNLNGELLLATAVFVGEVRLIDNEVLVSP
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAU12_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYSFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-12.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARNT_ECOHS
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWRGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPNFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAD_BACLD
Sequence: MASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQDIPNVQVESFQGLLIDYAKSKQANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMTNNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAKNERP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHB_MYCVP
Sequence: METARLLFVHAHPDDETLTTGATIAHYVARGAQVHVITCTLGEEGEVIGDEWAQLAVDRADQLGGYRIGELTAALAELGVDRPRFLGGAGRWRDSGMDGTPARQQQRFVDGDFAEQTATLAAAIDELRPHVVVTYDPNGGYGHPDHIHAHRVTTAAVAASTWQVPKLYWTVTSSSALAAALASMGAVPEEWIRVSADDLPLFGYSDEAIDAALDLTAHESARVAALRAHRTQVSVSPDGRSFALSNNVALPVDPTEYYVLAAGSAGARDERGWETDLLSGLSVG
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: Y572_CHLPN
Sequence: MAAPINQPSTTTQITQTGQTTTTTTVGSLGEHSVTTTGSGAAAQTSQTVTLIADHEMQEIASQDGSAVSFSAEHSFSTLPPETGSVGATAQSAQSAGLFSLSGRTQRRDSEISSSSDGSSISRTSSNASSGETSRAESSPDLGDLDSLSGSERAEGAEGPEGPGGLPESTIPHYDPTDKASILNFLKNPAVQQKMQTKGGHFVYVDEARSSFIFVRNGDWSTAESIKVSNAKTKENITKPADLEMCIAKFCVGYETIHSDWTGRVKPTMEERSGATGNYNHLMLSMKFKTAVVYGPWNAKESSSGYTPSAWRRGAKVETGPIWDDVGGLKGINWKTTPAPDFSFINETPGGGAHSTSHTGPGTPVGATVVPNVNVNLGGIKVDLGGINLGGITTNVTTEEGGGTNITSTKSTSTDDKVSITSTGSQSTIEEDTIQFDDPGQGEDDNAIPGTNTPPPPGPPPNLSSSRLLTISNASLNQVLQNVRQHLNTAYDSNGNSVSDLNQDLGQVVKNSENGVNFPTVILPKTTGDTDPSGQATGGVTEGGGHIRNIIQRNTQSTGQSEGATPTPQPTIAKIVTSLRKANVSSSSVLPQPQVATTITPQARTASTSTTSIGTGTESTSTTSTGTGTGSVSTQSTGVGTPTTTTRSTGTSATTTTSSASTQTPQAPLPSGTRHVATISLVRNAAGRSIVLQQGGRSQSFPIPPSGTGTQNMGAQLWAAASQVASTLGQVVNQAATAGSQPSSRRSSPTSPRRK
What are the official names of this protein?
Uncharacterized protein CPn_0572/CP_0177/CPj0572/CpB0594.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0572/CT_456/TC_0741 family.
Protein: RTC5_BLAGS
Sequence: MGGALSTEAQRASSVEELSQRLAHRFATKCFTPLELTHLKDNFFSRALEQRGIRYWNEEILSDFLGIPDGAGSAATATSDGSLDAGPVIFRMVSYLGAFPFQNTMAPTVLTFEAMIKVVVLLTERYGKVLKRGKKDRIKLLFGSLADVGRRDIITQLKEAAEDSLESIGVADPNGGSTFAHNGGFLIDQPINDGEDEDDDDDLALAALESLDAIEVFKQDQRIDKTVFESKISLTTFRRLLTLLIVTAPLRPLGTVSKYTTGLSKSSLDTVHEQVDSILAALGSEVAEDGIGYKSFSELISTSLPYLFDPLTPLFEHLLFSKNLNLSRKSETSNGQADKPAPTPPSTPPRSPPLSPVILTGGFDSCILNPVILSHLSFFISTSPHIPNIFRNRTHLHPVFSSTEHGESLTSFSHHVMTWQAPTILLIRGAVTSENNEEQITTIGAYIPQPWKQSSSYSSRRSSESVHPSTLPCLFEIFPVHTVLQGSPSFSSLKSNMPVSHFSTKTGIAIGCIIPPSSRKSLGSDLHPKPAGGGSLLIDSALENATFVVSDGLNGEGVFLPPGVSPSGTTTTGTTSTKTPSSTSPTASAASVSTSNHNTTKSISIYNLEVWGIIPSQSLATQSDGTGSPIEKQDAIALQRAQWNFEAREAERRQAINMKVGGGESEAQTGRALLEMAGIIGDSQYSAHPHH
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN_EBVB9
Sequence: MADVDELEDPMEEMTSYTFARFLRSPETEAFVRNLDRPPQMPAMRFVYLYCLCKQIQEFSGETGFCDFVSSLVQENDSKDGPSLKSIYWGLQEATDEQRTVLCSYVESMTRGQSENLMWDILRNGIISSSKLLSTIKNGPTKVFEPAPISTNHYFGGPVAFGLRCEDTVKDIVCKLICGDASANRQFGFMISPTDGIFGVSLDLCVNVESQGDFILFTDRSCIYEIKCRFKYLFSKSEFDPIYPSYTALYKRPCKRSFIRFINSIARPTVEYVPDGRLPSEGDYLLTQDEAWNLKDVRKRKLGPGHDLVADSLAANRGVESMLYVMTDPSENAGRIGIKDRVPVNIFINPRHNYFYQVLLQYKIVGDYVRHSGGGKPGRDCSPRVNIVTAFFRKRSPLDPATCTLGSDLLLDASVEIPVAVLVTPVVLPDSVIRKTLSTAAGSWKAYADNTFDTAPWVPSGLFADDESTP
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.  Also acts as a cytoplasmic RNA endonuclease that induces degradation of the majority of the cellular messenger RNAs during early lytic infection.  The resulting inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and evasion from host immune response.  Internally cleaves host mRNAs which are then degraded by the cellular exonuclease XRN1.  Bypasses therefore the regulatory steps of deadenylation and decapping normally required for XRN1 activation.
What are the official names of this protein?
Shutoff alkaline exonuclease, SOX.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: NEU1_SHEEP
Sequence: MAGSSLACCLLGLLALTSACYIQNCPLGGKRAVLDLDVRTCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCREENYLPSPCQSGQKPCGSGGRCAAAGICCSPDGCHADPACDPEAAFSQH
What is the function of this protein?
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  Acts by binding to oxytocin receptor (OXTR) (By similarity).
What are the official names of this protein?
Oxytocin-neurophysin 1, OT-NPI.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
Protein: GLPE_YERPY
Sequence: MEQFEAISVEQAYLRWKEGKTALVDIRDPQSYEAGHAPGAFHLTNSSLHTFMQQTDFDQPVMVMCYHGNSSKGAAQYLLQQGFDVVYSIDGGFEAWARSYPQDITSESR
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_METKA
Sequence: MAERPEERQWKEWEEAGLFEADPDDRESVYITVAYPYPSGSMHVGHARTYLVPDIYARFKRMQGYNVLFPMAFHVTGTPVVGIAERIKEGDEDTIRLYRDLYGVPEEELEKFTEPEAIVEYFAREYEENMKRMGYSIDWRRKFTTVDPEYRSFITWQYLRLREKGLVDKGEHPVRYCPHCENPVGDHDLLEGEDATIEELTLVKFPVEGDDLILVAATFRPETLYGATNVWVKPDEEYLVVEVDGERWVVSEEAYRNLRHQKDGVEKVDTVRGEELIGESVVNPVTGEALPVLPAEFIDPKFGTGVVYSVPAHAPADAAALEDLKKDPSVLEEYGVDPSVVEELEPVQVIEVEGYGEFPAYDALEEHGIESQTDPELEKATQEVYRAELHKGVMVVDEFEGTPVREAREEIKSRLIESGDADVMYDFSEKPVICRCGTECVVRILKDQWFLRYSDGEWKERAEELLGRMEIVPEEVRANFEDTIEWLDDWACARRVGLGTPLPWDPDWIVEPLSDSTVYMAYYTIAHRLKGKGELPPEVFDYVFLGEGDPEEIAEKAGLDVEELEAMREEFEYWYPLNWRLSAKDLVTNHLTFFIFHHAALFPEDKWPKGIVVFGMGLLEGQKMSSSKGNVVLLSEALDEYGPDVVRLFLATSAEPWQDFDWRDEYVRGVQRHLERFETLIRDHADESVEDKDAVDRWFLHEFREVVEETTEALEGFQIRRAYNRAFYGVMKLLREYEAMKGHVKILGEIAEDWLKLLHPVIPFATDRLWREVLGEDSFLLEEEWPDPSEYPEEPELSVAKEVLDRLIEDVRDVEKVIGAEPGYTLHVYLAPEWQWRALELILKDKEFGEVMSELMKDEGLREKGDEVAKIVQELTKEDLPEDVDVDALREALTEFLEAAGRALTDKTGASEVVIHTDPEEAPGPEDRKAGARPLRPGIWLEE
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_STRPB
Sequence: MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDLSLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYGNKIDQLLRELDNKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_LISMF
Sequence: MTIYHFVGIKGSGMSALAQILHDKGFQVQGSDVDKYFFTQKALEEKQIPIMTFSADNIQEGLTIIAGNAFPDTHEEIERALELGLPVIRYHKFLGQLIDGYTSIAITGSHGKTSTTGLLSHVVGAIRPTSYLIGDGTGSGTKGAEYFALEACEYQRHFLAYKPTYAIMTNIDWDHPDYFKSVDDVFNAFETLGKQVKKAVFALGDDAELRKLTLDIPIIYFGFGEENEFQAKNVIKETTGTKFDVYHRGEFLGSFEIPAYGDHNVLNALSVIALCDYEGLPVEDVKKELKTFEGVKRRFSITEKANQVLVDDYAHHPSEIRATVNAARQKYPDKKVVAVFQPHTFTRTRTFLQGFADSLNLADEVYLCDIFGSAREKTGNLTIADLAHKTKGNHIIKEEHTEELLKYPEAVILFMGAGDVQKFQAAYEKVLDHEVLTEADLKKSAIN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITRA_ALBJU
Sequence: KELLDADGDILLNGGXYYIV
What is the function of this protein?
Inhibits trypsin and alpha-chymotrypsin.
What are the official names of this protein?
Trypsin inhibitor A chain.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: POLR_KYMVJ
Sequence: MAFQLALDALASTSHKDPSLHPVLESVHDSLTDSLQTYPWMVPQDLQPFLLKSGIPINSFGSSPHPHPAHKTLETHLLFTHWMHLCTQPSSVLFMKPQKFMKLQRKNKFFQHLHNYRLTPTDSVRFPSTSPHLPNTPFVFMHDALMYYQPEQILHLFHQVPQLTNLFCSLVTPPESHFTHLSLMPDLYTFTLKGQTLHYTPEGHSAGSYNQPITALSWLKINSILSPNLNLSITILESWGPLHSILIQRGLPLPDPKLLVRSLPPFSRSPDPETDLVSFQVPKSVELPQATFLSQPLRHRLVPESVYNALFTYTRAVRTLRVSDPAGFVRTQSNKPEHKWVTPSAWDNLQTFALLNCPLRPNVVYHVLLNPLQKMKLYFSQHWRRLGVIAAPGLFCLSLLLRSQKWSLPLPKAKSISVFRRNLLLPPKPHRPPLLPHPEQMLQEFKLPWHRPPPKGKRNPFLTLLINLLHIPREICAGIRRYPSYYQSIQPKPLNPIQQFRNQLLAQLHTLPLPKKFLSILPRARKDIPLLPRMSFTTVNLPLQPPMWLAIGASLVPELAFLLSWLSGDVDLQTQHDIYHHHLHPENFTLSWTRTPYLALAPSPFLPYAHSPLPPLPVNSSPLFPPPPPLPPSQPPLSQGPATQAPSAQPTPGEPLLAPPTTELKPESSNPNNPNPSSSAGSNPPPKSSSSDNPPAPNKPTPTSSSTTPPSPNLPLQFGSIHSPFLSDGQLNYSALPPPQDPTNTTLSLLPEPKPPTEVQSPLMADPTCVGPAVSFSSLYPRDFFPNTASFLTRLRLSPPTPLPMPKNNCLLTAVAPSLHINPHRLWTSLQEVLPDSLLSNSEIDSVGMSTDLLTALSHLFNFQAVVHSERGDILFGLQSAKTVIHIYHTNGPPAHYSPPPKIIGSNSPPSSQQHPLEQAALRFKYQGSHLPFSSFHSFTTSVQHAKNLISNMKNGFDGVMSTIEPSIRHQPGHSPREKFIALDAMIDLARPKTVSMFHLAGFAGCGKTKPLQSLLSTRPFHSFRVSTPTTELRNEWKKDMNLPASQAFRFCTWESSLLKQTKILVIDEIYKLPRGYLDLCILADPCLELVIILGDPLQGEYHSTSPHSSNHQLQSETTRLLPFIDHYCWWTYRVPSHIADLFSVPSFNRSEGHYQMAVRTADSYTPGHFNLVNSVATANAVIQLGFPATTISASQGVTHHNRVTILLDKHSRLLSPSNTLVALTRSTVGVEFLGDIGSLSGTNNSSDMFSRAIYRQPINLSSSFPRIFHLLPLLNKPISRRSTRLIGSHSPIFHNPRLTNIHLPPHIPTSYSQDFVVSNPIFQGQADPRLDTHFLPPTRLPLQSELLPAQLSQTTKPTDSFTNNTPFTPVYPGENFENLAAFFLPAHDPELKEVTRRDQTSAQFPWFDRPFSLSCQPSSLIAAKHSPSQDPTLLPFSIPKRLRFRKSDNPHVLSAIDVLLGNQLFFNLCKAYRRNPTHVGPFNPALFAECIALNDYAQLSSKTQATLVANHSRSDPDWRHTAVKIFAKSQHKVNDASIFGNWKACQTLALMHDFVILSLGPVKKYQRIFDALDRPPHLYTHCGKSPADLSAWCQTHLTGQIKLTNDYTAFDQSQHGESVILEALKMKRLSIPSHLIQLHVHLKTNVATQFGPLTCMRLTGEPGTYDDNSDYNLAVIHSQFDMKDIPVMVSGDDSLIDRQPPLAQSWEATKRLLHLRFKTEKTTHPLFCGYYTGSAGAIRNPLALFSKLMIAIDDEAIHDRRLSYLTEFSTGHQLGDALWTLLPESTQIYQSACFDYFCRHSPPHEKALLSSFELPDSVISKISSSTKWLSKNAFYALPSKIRKAVIASRHSSSFPENPDVSQLEFELLQSFQF
What are the official names of this protein?
RNA replicase polyprotein.
What is the protein family that this protein belongs to?
Belongs to the tymovirus NS35 RNA replicase polyprotein family.
Protein: MNTH_MYCLE
Sequence: MFVNLTCLSEGNGSRGKALAESTQAELKTSWYLLGPAFVAAIAYVDPGNVAANVSSGAQFGYLQLWVVVVANVLAGLVQYLSAKLGLVTGQSLPQAISKQMSHPFRLGFWLQAELVAMATDVAEIVGGAIAFHILFRVSLLLGGVITGTVSLLLLMVKDRRGQLLFERVITGLLFVIVVGFTSSFFVATPSPEDMVNGLLPRFQGTESVLLAAAIIGATVMPHAVYLHSGLALDRHGHPHAGRSRRRLLRVTRLDVILAMTIAGIVNTAMLLVAAINLQHHQVTAYIEGTYTAIQDTLGATIAMLFAIGLLASSLASASVGAYAGALIMQGLLQRSIPMLIRRLITLCPAIAILALGFDPTRALVLSQIVLSFGIPFAVLPLVKLTNNRGLMGNDTNHPATTVLGWAVAILVSLLNVVLIYLTVTS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROK_LEPBP
Sequence: MMNIILIGARGAGKSKVSRSLSKQSEIPVVSTDSVAVYETGGIPIPKFVENNGWKAFRELEYSILQKLQNANGIILDCGGGILFDLDESGNEVLSERKLDLLRKIGRIVYLERGIEELVEKVKGDKTRPDLSKITTYRSILEKRLPVYQEAAHFKLNLTKLSKEEAAEKILDWIGIKSKSI
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE128_MOUSE
Sequence: MAESSSDSDHVRYRDGLSRWATRSFQRGVGSHSTVDVTAKVNTITNTLQDTTRNLRHVDQMLGRYREYSTGQAGAVGQLKEDLEQSINQLRSQRLRRSSGGRSVSVTSLSASDLDGGAVTENLRFAPTSPLKDYDLQGIKRNRFRTGVRFVSETDDMVQLHTFHQSLRDLSSEQVRLGDDLNRELFRRSRSDAETKRVLEELTGKLNEVQKPDVVSDRVERRLQEIEREMRLERELVERRHDQLGLVSLKLQEALKKQEAKADENEDVIKRKLRQSETEKSQLEQELEISRRLLSQSESNRETLLHQVEELRTQLIKAEGDQRGLQHQVPCISKQPLSHQDDQGDDRRFRRGVEREKLSLEKQMADLRVQLNFNSMASELEEVKRCMERKDQEKATLAAQIENLTRDLENREKQQLQMLDQLTEIQNHFETCEANRKRTDLQLSELSQHAEEATKQAEHYLSEFQRSETLREEAEKRREDLKAKAQESIRQWKLKHKKLERSMEKQAETLVQLTEKNNQFIKERDELKSQLCAALQQIENLRKELNDVLSKRALQEEELHCKEKKLNDIESHQAELELEVKNSLDTIHRLENELKRQSKSQSQIKAEKIHLEEEITELKKSQSQDKVKLLEMQESIKDLSAIRADLANKLAEEEKAKKAVFRDLSELTAQVKSKEEETATAITQLKLERDVHQRELEDLSSSLESVKLKHEQNIQELMKHFKKEKSEAESHIRMLKAESLEDKNMAKAHLGQLEKLKSQCEKLTEELTHTENENKKLKLKYQSLKEELDKKEKYISTEEEHLRRMEESRLHLKDQLLCLETEQESILGVIGKEIDEACKTFSRDSLEKLKVLTSGPQLHYDPHRWLAESKTKLQWLCEELKERESRERSMRQQLAACRQELRELTEHKESELLCLFEHIERQEQLLEEFHQEKRGLLEETQRKDEEVETLQDRVNALQMSTRVALDHLESVPEKLSLLEDFKDFRGASSLSEKTDGRYSKYSLHGDSVQQRRDDTKPRIKSFRDDRPLSAGSHAHGLDHSSSCQDHSRFLSSPQFSHSLPVFTKRTIATDPASIEGDTTSLPANGTSPQSKKEEHEIKKYKK
What are the official names of this protein?
Centrosomal protein of 128 kDa, Cep128.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with the mother centriole.
Protein: NUOA_TRIL1
Sequence: MLGTYLPIMLLILVALAFGLGSVVFSSLIGQKKFSKVKMAPYECGCEPIGTARERFPIKFYLIAMLFILFDIEAVFLYPWAVLYKKLGLFGLVEMGLFVVILFVGYIYVWKKGALEWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YVDA_BACSU
Sequence: MNQMVSLTSILEHNQRFVSEKKYEPYKTTKFPSKKLVIVTCMDTRLTELLPQAMGLKNGDAKIVKNAGAIVSHPFGSVMRSILVAIYELQAEEVCIVGHHECGMSGLNASSILEKAKERGVEDSCLNLLTSAGLDLKTWLTGFHSVEESVSHSVNMIKNHPLLPKKVPVHGLVIHPETGKLDVVINGYETELINNHS
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Putative carbonic anhydrase YvdA, Carbonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: RL3_METTH
Sequence: MARHHQPRKGSVAFSPRKRAARETPRVKSWPQVDEPGLLALAGYKAGMTHVMMVDNQKNSPTEGMEVSTPVTILEVPPLTVMAVRTYEKTSRGLKTLGEVLATETKDDLRRKLTPPADDYDQEAAIEKIRSNMEYVADVRVIVHTNPRLASVPKKKPEVFECGLGGKTPEEKFEYALEILGKDVRASEIFSEGAFVDAIAVTKGKGFQGPVKRWGIRIQYGKAARSSKGRHIGSLGPWTPSRTMWTVPQAGQMGYHRRTEYNKQILKIGDASEADLVNPDGGFVRYGLVRNDYVMIKGSVPGPTKRLVVLRKAIRAAGKQEEAPQINYISTASKQGV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.