PharMolix/UniProtQA huggingface dataset:
Protein: LOLD2_EPIUN
Sequence: MTTVVREAFENHVKLVESRNSPGHVLASSEASFFVADLNDVVRKWAAWKEALPDVTPFFAVKSSYDRRLIQTLATCGAGFDCASTEEIELILSLGIGAERIIFTHPCKPVSSLGLCRKLGITLITFDNECELRKLHHHYPEAQTVLRVFADDPTNADPLGTKFGAARDDFDGLVRLVKELNMQLAGASFHAAPSVAVDAAAYVRGIRDTAEVFARARQVGLNPTVLDIGGGYTDSTFQQIAGAVRPAIAECFKSEVGEGRLRILAEPGTLFSCSPFYLAVKVVARRVNATAFGHEPATRLYINDGIYSNFMMRFIVNMTFSPAAVIREGVWHDQADHTMRGEACSLWGRSCDSNDCINRDCRLGPEVRVGDWLVFKDMGAYTTVCNTTFNGFTSSNHTIYLEPGTHPSRRSPVDL
What is the function of this protein?
Amino acid decarboxylase; part of the gene cluster that mediates the biosynthesis of loline alkaloids, potent insecticidal agents composed of a pyrrolizidine ring system and an uncommon ether bridge linking carbons 2 and 7 (PubMed:15654104).  Lolines are structurally differentiated by the various modifications of the L-amino group and include norloline, loline, N-methylloline, N-acetylloline, N-acetylnorloline, and N-formylloline (PubMed:15861432, PubMed:25531527).  The first committed step is the condensation of O-acetyl-L-homoserine (derived from L-aspartic acid) and L-proline, probably catalyzed by the gamma-type pyridoxal 5'-phosphate(PLP)-dependent enzyme lolC, to give the diamino diacid, NACPP (PubMed:15861432, PubMed:16755627).  Ensuing cyclization, decarboxylation, and acetylation steps yield 1-exo-acetamidopyrrolizidine (AcAP)(PubMed:24374065).  LolO is required for installation of the ether bridge upon the pathway intermediate, 1-exo-acetamidopyrrolizidine (AcAP) (PubMed:29537853).  In sequential 2-oxoglutarate- and O(2)-consuming steps, lolO removes hydrogens from C2 and C7 of AcAP to form both carbon-oxygen bonds in N-acetylnorloline (NANL), the precursor to all other lolines (PubMed:24374065, PubMed:29537853).  The enzymes lolD, lolE, lolF and lolT have also been proposed to be involved in the ether-bridge installation (PubMed:15654104).  Further processing of the exocyclic moiety of NANL by fungal N-acetamidase (LolN), methyltransferase (LolM), and cytochrome P450 (LolP) enzymes, with occasional involvement of a plant acetyltransferase, generates the other known lolines (PubMed:25531527, PubMed:18655839).  LolN transforms NANL to norlonine which is monomethylated and dimethylated to respectively lonine and N-methyllonine (NML) by lolM (PubMed:25531527).  LolP catalyzes hydroxylation of the methyl group in N-methylloline (NML) and further oxygenation to N-formylloline (NFL) (PubMed:18655839).  A plant acetyltransferase is responsible for the acetylation of loline to form N-acetylloline (NAL) (PubMed:25531527).  LolA might interact with aspartate kinase to prevent feedback inhibition of its activity by these end products and thereby promote production of L-homoserine from L-aspartate (PubMed:15654104).
What are the official names of this protein?
Amino acid decarboxylase lolD2, Loline biosynthesis cluster 2 protein D.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: XYLB_ACTM4
Sequence: MALVAGIDSSTQSCKVVIRDAETGALVRQGRASHPDGTEVHPDAWWSALQSAIEEAGGLDDVAAASVAGQQHGMVALDENGEVVRPALLWNDTRSAGAAADLIAELGGGEKWAEAVGIVPVASFTLTKLRWLARNEPANAAKVAAVCLPHDWLTWKLSGSTDIADIKTDRSDASGTLYWSAKTNEYRRDLLELGFGRDLVLPEVLGPTGIAGHLPNGAPLGPGAGDNAAAALGTGALPGDVIVSIGTSGTVFVSSDVAPVDGRGTVAGFADTTGRFLPIVVTLNAARVLDAAAKLLGVDHDELSRLALSAPAGADGMVLVPYLEGERTPNRPDATGAIHGLTLKTSDPAHLARAAVEGMLCALADGLDALVAHGAEANRIVLVGGGARSEAVRRIAPALFGKPVLVPPPGEYVADGAARQAAWVARGGDTPPAWSAASPEVYEDDPVPLIREQYAAAQNAVIDRTR
What is the function of this protein?
Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.
What are the official names of this protein?
Xylulose kinase, Xylulokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: CAZA2_CARPS
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDVGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTAQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVETAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: SPR28_YEAST
Sequence: MFPMKDHSALEQHTLSRDELRRRKGYKKGLQLSILLLGEKGSGKSTFLNNLCGQDISLSDGDYDDDDDKVTNNVTPENGNAIEDIDPGYKTAHLSPGLKLVTRRVYLNDELGVPITLDIILFPGCGDNVDNSQSSVVIKNYLDQQFANVLKEEVRIKRNTKETDGRPHVCLYFLKSTPRGVKKFDIELMKTICDKVNLIPIIPKADGLTETELNLHKDIVRQEISQNNIRVFDFKSDTLGETLALYDMDIDSSSAKSKYDNDTKIKEISPFAIVCSKTFNKNSENRVEHIRTYEWGSLVVEDQNTSDFIYLKAILLGSHLQELKDVTNNVLYENYRAKVLTEKKNNYDIPNYSYIDETSRGSVSNVSTRRNSASRTLGNPDTNDENAYQIHKEIDEKNRIIEDYQRKIDLLEKMLAAPHQNKV
What is the function of this protein?
Septins are GTPases involved in cytokinesis that assemble into filaments and form a ring at the cleavage site.  May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage.  Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).
What are the official names of this protein?
Sporulation-regulated protein 28.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Bud neck. Note=Present at the bud neck during cell division. Probably interacts with phosphoinosides such as phosphatidylinositol 4-phosphate or phosphatidylinositol 5-phosphate (By similarity). Localizes to ring-like structures around each of the four nuclear lobes at the onset and during meiosis II. Concentrated initially at the leading edge of the developing prospore wall.
Protein: ISPD_SYNJA
Sequence: MHLLIPAAGSGKRMGAAVNKLLLPLLGQPILAWTLQAADRASSIEWIGILSQPGDWPAIEQILAAMDLSTPVQLLQGGATRQESVYRGVEYLYNLGTVERVLIHDGARCLATPKLFDRCSAALQQVDGLIAGIPVKDTIKVTETGPKGIQIQSTPERSRLWAAQTPQGFRLSLLWQAHREALAQGWQVTDDAALFEKLGWPVYIVEGEESNLKLTTPWDLVLAEQILQQRLELAR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: ATPA_RICPR
Sequence: MKLNPIEVAEILQKEIANINFLSELEEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVKGLILNLENDSVGAVIMGDYSKVKQGDNVKRTKDVLKVLVGKALLGRTVDALGNPIDGKGDIVSKEYRHIEMKAPGIIERMSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVLATASEAASLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSKEKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESDLFYKGIRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRERESFSQFGSDLDPATKAQIEHGKRLVEILKQDQYHPCPVEEQIVSIYVGTKKYLNDIPIQKVKEFEEAMLAEIRLNKKDILESIKTEQCITEEIEQKLKAFLENFIQAYCVML
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RHAG_RAT
Sequence: MRFKFSLIALSLEVVMIVSFALFVEYETSQNGSQKSASQQNASQQNAAAQQNASQQGNASSPAKEDQFFQLYPLFQHVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIVQGLLHSHGLKFPFRIKNMINADFSTATVLISFGAVLGKTSPIQMIIMTILEIAVFAGNEHLVTEIFKASDTGASMTIHAFGAYFGLAVAGVLYRSGLKHGHPNEESVYHSDLFAMIGTLFLWMFWPSFNSAIAQPENNQYRAIVNTYMSLAACVITAYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYFAMTIGSIAGIISVLGYKFLSPLLAHKLMIHDTCGVHNLHGLPGVFGGLASIVAISWGKSTVSTMAMQATALGSSIGSAIVGGLVTGLILKLPVWNQPPDEYCFDDSVSWKVPKYRELDNYFFQHVTHNHVEHEV
What is the function of this protein?
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.  Involved in ammonia transport across the erythrocyte membrane.  Seems to act in monovalent cation transport.
What are the official names of this protein?
Ammonium transporter Rh type A, Erythrocyte membrane glycoprotein Rh50, Rhesus blood group family type A glycoprotein, Rh family type A glycoprotein, Rh type A glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: GATB_HALH5
Sequence: MNFETVIGLEVHVELKTESKIFSASPNHFGAEPNANTSVIDLGYPGVLPVLNKAAVEFAMKAAMALNCEVATDTKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGTKKKIGITRLHLEEDAGKLTHSGNGYSLVDFNRQGTPLIEIVSEPDIRTPQEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEEFGTKTELKNLNSFNFVRKGLEYEEKRQAQVLLSGGEILQETRRYDEAANKTVLMRVKEGSDDYRYFPEPDLVALHIDDEWKARIRSEIPELPDARKKRYVEELGLPAYDAMVLTLTKEMSDFFEETIAKGADPKLASNWLMGEVSGYLNAEQKELDEVALTPDGLAKMIQLIEKGTISSKIAKKVFKDLIEKGGDPEEIVKAKGLVQISDEGELRKYVVEVLDNNQQSIDDFKNGKDRAIGFLVGQIMKATKGKANPPMVNKLLLEEINKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PYNF_ASPNC
Sequence: MSHDQRSPSEEVSRTALSKPASESTIVGDGHHPLPAKDTSTRAWLVVVGGLLIYFPTFGFLNAFGTFQTFYVQDLLAGTSSSKIAWIGSLQIFLLFIGGLVVGPLYDKVGATKLLVPGSVVYVVALMLTSVCKKYYQLILAQGILFGCANALLFYPTIAAINQWFDRRRGIALGLAVSGSSLGGIFWTEIIQLMLDHIGFGWTVRACGFISLAFLVPSCVLIITRPPEPGESKDMQLDFKAIFTDTKYLLFSVGMLLVLWGMFIPFFYLPSYGETYGMSVTGANNLLAYMNAGSFVGRVLTGLMADRLGRFNVISLAALSCGILLFCLHKITTSGAIIAFSTLYGICSGGLISLQSACIGQITPDHSIIGVKIGLMMGFCSVGGLTGSPIAGALLSADHQKWYGFIDFCGSILMGGAVVTILSRYVAAPREWKF
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of pyranonigrins, a family of antioxidative compounds (PubMed:24106156, PubMed:26414728).  May be involved in the secretion of pyranonigrins (Probable).
What are the official names of this protein?
MFS-type transporter pynF, Pyranonigrins biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH1_MYCUA
Sequence: MTQLDSRTEATTTRAFDQPRAEAAVRELLLAIGEDPDRGGLRDTPARVARAYREIFAGLYTDPDAVLNTMFDEDHDELVLIKEIPLYSTCEHHLVSFHGVAHVGYIPGRDGRVTGLSKIARLVDLYAKRPQVQERLTSQIADALVKRLGPRGVLVVVEAEHLCMAMRGVRKPGAVTTTSAVRGQFKTDAASRAEALDLILRK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ECP_MACFA
Sequence: MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTKAQWFAIQHINVNPPRCTIAMRVINNYQRRCKNQNTFLRTTFAYTANVCRNERIRCPRNRTLHNCHRSRYRVPLLHCDLINPGAQNISTCRYADRPGRRFYVVACESRDPRDSPRYPVVPVHLDTTI
What is the function of this protein?
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity.  Possesses a wide variety of biological activities.  Exhibits antibacterial activity (By similarity).
What are the official names of this protein?
Eosinophil cationic protein, ECP, Ribonuclease 3, RNase 3.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Protein: KCC4_RAT
Sequence: MLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY
What is the function of this protein?
Heat-stable, acidic, calmodulin-binding protein.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type IV, CaMK IV, CaM kinase-GR, Calspermin.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized in hippocampal neuron nuclei. In spermatids, associated with chromatin and nuclear matrix.
Protein: ACSA_PHYB8
Sequence: MLDKTTIDGQEDIVTHPVPKRLLNSAECPTPHVNSLEQYKSMWKESVEQPEKFFGNLGRELLSWSKPFETVQYGSFEAGDVAWFLEGELNASYNCVDRHAFKNPDKIAIIHEGDEPDQVRRITYGELLREVCRMANVLKGLGVRKGDPVAIYMPMIPETIVAILACARIGAIHSVVFAGFSAEILRDRVVDCATRVVLTSDEGRRGGKNIATKCIVDEALRDYENHSVEHVLVFRRTGSPVPWVQGRDVWWHEEMAKARTFCSPEPMSAEDPLFLLYTSGSTGTPKGILHTTGGYLLGVAATVKYIFDYQENDIYACMADIGWVTGHSYIVYGPLTLGATTVLFESTPTYPNPSRFWQLIEKHKITQFYTAPTAIRALQRLGDQWLDNIDMSSLRVLGSVGEPINREAWDWYNEKVGKGRCAVVDTYWQTETGSIIVSPLPGATPTKPGSATLPFFGIDPVLLDPTTGKELTATGQTGVLAIRKPRPSMARSVYNNHSRFVETYLKPYPGYYFTGDGALRDDDGYIWIRGRVDDVINVSGHRLSTSEIESALVNHEAVAESAVVGAHDDLTGQCIHAFVSLKPHIQIADGLEKVLTLQVRKTIGPFAAPRRIYIVSDHPKTRSGKIMRRILRKIVNGEHDQLGDISTLADPSIVAVLINKVQRLNTEANIYI
What are the official names of this protein?
Acetyl-coenzyme A synthetase, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ENO_CLAMS
Sequence: MAAIEAVNAREILDSRGNPTVEVEVLLEDGTFTRAAVPSGASTGAFEAYELRDGDAGRYLGKGVQKAVAAVVDEIGPAIQDLDAADQRIIDATMIELDGTENKSRLGANALLGVSLAVAKAAADSAELPLYRYLGGPNAHTLPVPMLNVINGGSHADTNVDIQEFMLLPVGASTFSEGLRWGVETYHALKSLLKKKGLSTGLGDEGGFAPNLDSNRAALDLLMEAIDAAGFTAGKQIALGLDVASSEFYSDGAYTFEGQKVDAAHLTAYFADLVASYPLITIEDPLDEDDWAGYDHFTAELGSKVQIVGDDLFVTNPKRLADGITRGVANSILVKVNQIGTLTETLDAVSLAQRSGYTTVLSHRSGETEDTTIADLAVAVEAGQIKTGAPARSERVAKYNQLLRIEQDLGAAAVYAGRSAFPRFQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FOSL_DROAN
Sequence: MTLDNYNIFNDEYLFGMPLSPLPKVLGTFDGIQLAPTLTTPTLTPTTTRSLQEAFFELTNDPGTPYQATFKPPPLGLMPGGNNGNGVTNVPTTTATATVVGVVNPMISQLPYEVNSALQGTDSDNSNASWADAQNNEDQDTTDTSSAHTDSTSYQNGHMAGSSVNGGGANNFTNVLAGINAGRGSTQGSNTNTSNSATPARRGGGRRPNRNTNMSPEEEEKRRIRRERNKQAAARCRKRRVDQTNELTYEVEQLEKKRDGLKKEMETLTDVKNQLEFFLRAHHSSCQKIRTDLLSVTTCNGLIAPVGLPSAGSCDSGSSSHHNNNSNDSSNGTITGLDASLNSTGRSNSPLDLKPQIKDEPLDGGLDSSCLLDQDGPPPSKRFPLPPMSTLMTPTGVSSGSLQTPIASTAPGGFGSAYPITTTKGSMNSPTLNELNKPKERPNTLAVQRPFVPQMHLNLTSNHNKMPGSGPTHIQGVPIQTPTTGFNFDSLMDGGTGLTPVSGPLVPSQNKHPLELPTPTAEPSKLVSL
What is the function of this protein?
Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'.  May play a role in the function or determination of a particular subset of cells in the developing embryo.  Is able to carry out its function either independently of or in conjunction with Jra (By similarity).
What are the official names of this protein?
Transcription factor kayak.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPIP2_CAEEL
Sequence: MNRPSQISQDVAQPLSNQHETAMMSSDEDSMSRDSGICELMDENTPVCFSSMSTESTTVQVEECMEIDEDENLQPGPVSRRQKKVTFRREKSSCQVRLFDESPTSHKMFMRPQAPLSVRSENQQLLQQRKRKFEKSEQSSDHFHLEPMSVEAMDDDEIVMMDQNTTKWEPGFRAPNHKKGRLTRSATAFPSLETFEEEEHEEQHHLNVKYHLKTVAKESSKGFRRITAETLRDIFFRLSEKEFDDKYILIDCRYPYEYNRGHIKNAINHFDRVTVSKIFYDENGRKRCNKIPIFYCEFSQARGPKMAYALRQVDRELNVNHYPKCDYEEMYVLDLGYRNFFFAANEANITNLCQPHAYCEMHDKEHTMELKKYNFHNKGQSVLRTVSMSRSFKSLPTGSAFNFVASSASFTSAPSTSTENIDTNDDCQKSRTPAVPRIASRRNLFSDPSHSPTNFAQFPLTCSRETPSPHKHPLTCPRFS
What is the function of this protein?
Required for intestinal cell division following the 16E cell stage of embryogenesis (PubMed:27104746).  Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1. 3 and by activating the cdk-1/cyb-1 complex (PubMed:27104746).  Plays a role in male tail development, via regulation of the cell divisions of the ray precursor cell lineages, perhaps acting together with cell cycle regulators cyl-1, cdk-1, cyb-3, and cyd-1 (PubMed:27923661).
What are the official names of this protein?
M-phase inducer phosphatase cdc-25.2, Cell division cycle-related protein 25.2.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
Protein: PYRG_FRATT
Sequence: MNSNTKIIFVTGGVVSSLGKGVTAASLATLLESRGLNVTMMKLDPYINVDPGTMSPLQHGEVFVTEDGAETDLDLGHYERFIRNKMTQANNFTTGKVYQSVLRRERKGDYLGATIQVIPHITDEIKRRICSGIADDVDVAIVEIGGTVGDIESQPFLEAIRQLRIELGRNRTLFVHLTLLPYIKVAGEIKTKPTQHSVKELRGIGIQADVLVCRCEKKFDDSEKRKIALFTNVDQDCIFTAEDVDTIYEVPLKYNQQGFDAKLVELLNLNAKEADLSEWQNVVNTIRDVKGEVTIAMVGKYVSLTEAYKSLNEALYNAGYKKGVKVKIKFVDSEDVNENNVESYFKDVAAILVPGGFGSRGVEGKIISIKYARENQIPFLGICLGMQLAVIEYARNILGIKDAHSSELEPTTANPVIGLITEWQAEDGTVHQRTHSSDLGGTMRLGGYKCVLKQGSRAREIYQADEVVERHRHRYEVNSNYVERLEEAGLIFSGRSEDNKLMELIEIPQHKWFIACQAHPEFTSTPRYGHKLFESYIQAAIENSNN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: BSHC_CHLL2
Sequence: MNTFLLDYHAILTPKKGFPALFKDYTSEGEARNRLISGCFHLDYLNESDYYRQLRQLESRPFDRELLATILRRQNTRYGCTELHLREIEKLRSPRCMTIVTGQQPGLFTGPLYTIYKALTAVVFAERQKTLFPEYDFVPLFWLEGEDHDYEESAHTAVFSAGGIMHFRPEPFRRMPDQMVAATCFGEDIRRIVADFLDQLQETGNKPLIASMLGDCCFPGNTLEMSFAQLMMHLFKNQPIVLLSSQDPDFKKLSRPVFLRELSTCPASSYNIIAQSSTLENLGYSAQSKPRAVNLFHINHHGQRQKIEYPEDNRFVITPDNIHLSRHQILELCQDHPERFSPNVALRPIVQDTLLPSFACIAGPGEISYLAQFRRNYEQFGLTMPFVIPRGSFTLVEPKFSRFMDKMLRISGKSGFSRKQIYHAFFSDLQTLKRNAERVGENPELDSLFFSIRDRIEKALKDLGPVLAKIDPTLEPMLAASTLQAMKTVDTIEQKARKAGRRKNEELIEQILKTETAFFPEGVPQERLINVFYYLNKYGMELIDTLKNLLAGHSTEAHLIVEL
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: TRPA_PSEPG
Sequence: MSRLEQRFAELKAEGRSALVTFVTAGDPGYDASLQILKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALEAGQTLAKTLQMVREFRVDNQTTPIVLMGYYNPIHRFGVEPFVAEAKAAGVDGLIIVDLPPEHDAELATPAQAAGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTDLPISVGFGIRTPEQAANIARLADGVVVGSALVDKIAQAKSADQAVNDVLSLCSALAEGVRGARR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: IXTPA_GLUOX
Sequence: MMRKLSPGSKIVLASHNAGKLREFSTLLAESGITVISAAELDLPEPEETEETFTGNAAIKALAAARASGLPALADDSGFCVSALDNRPGVYSARWGGPTKDMQVAMERVHREMGDNPDQRAFFVAALCLAWPDGETRTVQGECHGTVVWPPRGDHGHGYDPMFVPEGESRTFAEMSEAEKNAVSHRGRALTAFLNTCLDTSTQKTERK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: Y3037_MYCTO
Sequence: MRARFGDRAPWLVETTLLRRRAAGKLGELCPNVGVSQWLFTDEALQQATAAPVARHRARRLAGRVVHDATCSIGTELAALRELAVRAVGSDIDPVRLAMARHNLAALGMEADLCRADVLHPVTRDAVVVIDPARRSNGRRRFHLADYQPGLGPLLDRYRGRDVVVKCAPGIDFEEVGRLGFEGEIEVISYRGGVREACLWSAGLAGSGIRRRASILDSGEQIGDDEPDDCGVRPAGKWIVDPDGAVVRAGLVRNYGARHGLWQLDPQIAYLSGDRLPPALRGFEVLEQLAFDERRLRQVLSALDCGAAEILVRGVAIDPDALRRRLRLRGSRPLAVVITRIGAGSLSHVTAYVCRPSR
What are the official names of this protein?
Uncharacterized S-adenosylmethionine-dependent methyltransferase MT3122.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: FBPC1_RHOJR
Sequence: MTYALEVDGVDKSFGGATILRGVAFAVESGSTTAIVGPSGCGKTTLLRLIAGFEKPDAGTIALAGRVVAGGGWAPAHRRSVGYVAQDGALFPHATVGANVGFGLPRRARTPARIAELLEMVSLDPSYAARRPDQLSGGQQQRVALARALAREPELMLLDEPFSALDAGLRANTRRIVADVLAKAAITTILVTHDQPEALSFADRVAVMRAGRLAQIGTPREIYSTPIDVPTAEFIGDAVVLSAHVDGSRARCALGDVAVAANGVHGNARVMVRPEQIELTPDGAGVSGTVVDVEYLGSEMLLGIRLNTADGMVPERVTVRRFGATTLTPGDRVGIRVLGKAVAYPA
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TREH_THEVO
Sequence: MKKIPHELTHMAFHGLVKYSDITVEGYPKIQYHGFIGNNRTAMLVAMNGYIDWGCLPNFNSNAVFSSILDKNKGGYFAIFPSDTTDVYVDQYYKEMTNVLVTEFVKNGKIILRLTDFMPDSEYGKISFPEVHRFVESFSEPIDITIDFKPTFNYGQDKPIIEKDQHGFIFTTDKESIGISSEFPLRKNSDRIFGNVKMEPRSSSWIIALYGIHHLFRTTDYKSYLRLQETTDYWRKWASSSSYAGAYHSMVMRSALALKVLFYEPTGLMVAAPTASLPEAIGGERNWDYRFTWIRDTAYVIEALSSIGYKYEATEFLYDMMDMITRDNRIRTIYSIDDSNDLEERIIDYEGYRGSRPVRIGNKAVDQLQIDQYGSIVRAIHSMAKAGGIVNSYLWDFVEQVMAKIEYLWKYPDSSIWEFRTEPKQYVYSKVMSWAAFDSAISMAKDLGLSAPIKQWKSIQDEIKKEVLEKGFDTDTNSFVQYYGSKNIDAALLRLPILGFIPANDEKFLGTLSRIEKELMVDGYLFKRYREDDGLKGDEGSFLMLTFWYIEDLILMKRLKKAREVLESVLEKANHLGLYSEEIDEKSGDFLGNFPQALSHLGVIRVAPKLEEALLKRTSKINS
What is the function of this protein?
Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose.
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.