PharMolix/UniProtQA huggingface dataset:
Protein: DSBD_HAEIN
Sequence: MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHTQQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTALLSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVAAIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRLWAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAENPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGSRVTGFMDADAFSNWIEKLL
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, C-type cytochrome biogenesis protein CycZ, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSC_DROME
Sequence: MMTPESKAIQPAAATTKQTAEATATTTMAHTQQKSQLSTLAKTTTTTATNKAAKSVVSNANSSGNNSSKKLALSQSQKTTTTTTPPTTTTTTTAAAAAEATTNADKMQKQQQLKQQLFAACSIKVKSENTLATTANAALAAATTTTTTATPALATGKAAKTILENGIKKESTPPAVESVEASSSSSSSSSSSSSSSSSWPTTRRATSEDASSNGGASADEEKSEEDPTAAVAASSTATTTSDLATTSRPRPVLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKPNIKSDTTLQAIVYKLVPGLYERELMRKRAFYKDRPEEAALATPEQRGDDTEHLIFSPSDDMSLSLEYAELGELKTDSEPELVDTLRPRYLQCPAMCRVSHLKKFVYDKFEIDAQRFSIDIMYKVKTIVLLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQERENQEQQLAVEVASSKVEPVSLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNMLDKREKSHSPQMSSKSSSKSSPCTPVSSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLKPEKESRSKKKDKDGSPKSSSSSSSSSSGERKRKSPSPLTVPPLTIRTERIMSPSGVSTLSPRVTSGAFSEDPKSEFLKSFALKPIKVKVESPERTLNNRAITPPSPSVQQSASPKSKGNNLDDSILMKPPSCMPPKSIASSKRKSKEPVKAVSKKQKLSPPLPTVDFKIRLPVTNGNSSGTASPKIEKPLMPPPAKPPMLAPRKLQPSAQFAPPPSPIHHHAGVQMSAPGNRTPIAKRYQPILPKASRPNPFANIPNDVNRLLKDAGTEIKSIGGGSVENNSNAAQKPHLYGPKGESKMGPPALPATTPSQGNKNVGKQAGNLPMSAPPNKGNSSNNYLNLALFNSSKCKGKEAPPGCRTPMYTPNSPIYSPSSPQYVPSYNIPTMPTYKYTPKPTPNSGSGNGGSGSYLQNMLGGGNGGSLGGLFPSPPTKSDQNTNPAQGGGGSSSATQSGGNNGIVNNNIYMPNEDAPEKQQVKVKSLLNSCNINIPSSLSITISRDNGDSSSPNNGQHPKHKSPVNNYIEIVKLPDQPQDQVQAAKEAQKRQSPPAAVPGHLAAKLPPPPPSKAIPSPQHLVSRMTPPQLPKVATPPPPSSPRVITPPKTSPPANAAKVTPLKPVLTPTQVDKKTPSPEKRTAAQMGSHSPTASENKSPKGGPAGVANSTGGAQNGDPAAKKFRPILPRQNGMPELAPKLPTLAPFVGFNPLQNPAAGKKVPPSKKSPNAGAAAHQSGQQKLVNGGQSQPAQQKTSPPAQKNQQQVKKVSKNPTPPPPSLPAVGKMMPHPVMHSQNAPLSIASSASAAAVASGQLDLSNFLKENLRRVHAAQAAQAAQVAAAANQSNMMYNLAQMGHMTPAMYNYQQAYFREQLSRMQRVGNEVFNDYLQKLKTAAATGGGGPVEGELKPMLPTVTLPSPGATPPAASPKTSPLPAGKLTAAATAPQTKGNSSSGAANARQQTAATGNNGATVPAASLPPATKSK
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility.  Needed to maintain expression patterns of the homeotic selector genes of the Antennapedia (Antp-C) and Bithorax (BX-C) complexes, and hence for the maintenance of segmental determination.
What are the official names of this protein?
Polycomb group protein Psc, Protein posterior sex combs.
What are the subcellular locations of this protein?
Nucleus.
Protein: ABITM_DICDI
Sequence: MRTLIERYYSQYYFIDTTITDPNLTEDQYVNQHTNELAVIGVAPSHPVLQQEISKIEFKENAINNEVSGVRKTGGFKLQSNTILCVITCSNGKEYFLRSCIKGKLLEINKELINNPSLLKTNHATSGFLAIVEPMIKDKFMENPGLIKFEEYHKLRNIPIQKGPVFLKDNTNDED
What is the function of this protein?
May regulate actin polymerization.
What are the official names of this protein?
Protein Abitram, Actin-binding transcription modulator.
What is the protein family that this protein belongs to?
Belongs to the ABITRAM family.
Protein: CPS2_ISORU
Sequence: MGIRLLKMHGYDVDPNALKHFKQEDGKFSCYGGQMIESASPIYNLYRASQLRFPGEEILEEATKFAYNFLQEKIANNQIQEKWVISEHLIDEIKLGLKMPWYATLPRVEAAYYLQYYAGTGDVWIGKTFYRMPEISNDTYKELAVLDFNRCQAQHQFEWIYMQEWYQSSSVKAFGISKKELLLAYFLAAATIFEPERTQERIMWAKTQIVSRMIKSFLSKENTLSLEQKTTLLIDFGHDINGLNKINSVEKGNGLAGTLLTTFQQLLEEFDRYTTHQLKNAWSQWFVKLQQGEGDGGADAELLANTLNICAGHIAFNEDILSHRDYTTLSSLTTKICQRLTQIQDKKILEIKDGSIKDKELEEEMQALVKLVLEENGGGIDRNIKQTFLSVFKTFYYCAYHHAETTDAHIFKVLFEPVV
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities (PubMed:28381502).  Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to (+)-copalyl diphosphate ((+)-CPP) (PubMed:28381502).
What are the official names of this protein?
Copalyl diphosphate synthase 2, chloroplastic, IrCPS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS17_PHOLL
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERKVKHPLYGKFIKRTTKLHVHDENNECGIGDVVEIRETRPLSKTKSWTLVRVVEKAIL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PLSX_CAMJD
Sequence: MINIAIDAMGGDFGEKPIIEGVLKALEAKPFNAILVGNSKILKPLIPKKLEQYIQYEEANEIFSMNENATDALKNKETTIYKAINLLKEKKVDAVVSAGHSGASMSLATLRLGRLKGISRPAIATLMPNIVSKTLLLDVGANTDCKAENLFQFAIMGEVYAREIMQIQKPRLALLSNGEEECKGNELTKESHQLMKKIPNFIGNAEGRDIFNGEIDVLVCDGFDGNVILKACEGVATAIFQLLKNEVKRSFISKIGALLIKPSFKKLKKHTDWQEYGGAPLLGVNGCVIISHGKSDSRAIKNAIFQAVNFSQSHINELIENELGKYNA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TCPA_SCHMA
Sequence: MLTLGGERTSGESVRKQNVLAACSFANFVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLDVEHPAAKILVQLAQLQDEEVGDGTTSVVILAAALLKNADELISRFVHPTTVINGYRLACREACKYIQEHMAYDVNKLGKAGLINVARTAMSSKLINLDADMFSQMAVDALMAVEVSGGPKGPVYPIKAVNILKAHGRSMSESMLIDGYALNCTAASQQMPRIIKKAKIAFLDFSLQKVKMKLGVQVVVKDPAQLEAIRQREADITKERIQKILNAGANVILTTGGIDDLCMKYFVEVNAMAVRRCKKVDLKNMAKATGGQLIVSLADMEGDEVFDPTKLGNAEEVSQERICDDELIILRGPKVHPSASIILRGANDFYVDEMERSLHDALLVVKRVLESKRIVPGAGACETAVSIYLENYALTLSSREQLAIAEFARAMLSIPKQLAVNAGVDSTELVARLRSCHNSSQSKPDQAHNKWWGLDLNNQYVADCKEIGVFEPLVSKIKSLKFATEAAITILRIDDLIKLKEEKQPDHDGDECGY
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit alpha, TCP-1-alpha, CCT-alpha.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_STAAW
Sequence: MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: KLC_DROME
Sequence: MTQMSQDEIITNTKTVLQGLEALRVEHVSIMNGIAEVQKDNEKSDMLRKNIENIELGLSEAQVMMALTSHLQNIEAEKHKLKTQVRRLHQENAWLRDELANTQQKFQASEQLVAQLEEEKKHLEFMASVKKYDENQEQDDACDKSRTDPVVELFPDEENEDRHNMSPTPPSQFANQTSGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQVLTRAHEREFGAIDSKNKPIWQVAEEREEHKFDNRENTPYGEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMRSKKEAYDLAKQTKLSQLLTSNEKRRSKAIKEDLDFSEEKNAKP
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
What are the official names of this protein?
Kinesin light chain, KLC.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MIAA_SALTI
Sequence: MNDVSKVSLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSALIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCSTRQLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PLH35_FORAG
Sequence: MESRINWGIIGCGNVAEVKSGPAFYKTENSTLVAVMRRNEDKVIDFANRHGVANWTTNAEALIQNDLINAVYIATPPSSHLQYALRAINVGKNVYLEKPMVLNNHEANILVEAVKRSNVKVTVAHYRRELPVYLKIKELLDSNVIGNVISAEIQIKQTRNTNLIAKTEVNWRTIPEISGGGYFHDIAPHQIDLMCHYFGEVENIKKGSCKENQVSHQDVSGEVLFKNGVQFSGTWNFNALEDKDECTIKGERGSISFSFYTSTITVSKNGLIESYHYENPEHVQQPMIEKTVGYFLAHNSNPCSVEEAAMVTHIMDVFCGT
What is the function of this protein?
Oxidoreductase that may be involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
What are the official names of this protein?
Oxidoreductase P35, P35_oxidoreductase, Polysaccharide utilization locus H protein P35, PUL H protein P35.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Cell surface.
Protein: FCHO2_MOUSE
Sequence: MVMAHFVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGFSIKPEANQNDTKENHFYSSSDSDSEDEEPKRYRIEIKPAHPNNLHHTMASLDELKVSIGNITLSPAVSRHSPVQMNRNSSNEELTKSKPSSLPTEKGTNDLLAWDPLFGSSLESSSAPLTSSSSARPTTPLSLGTLVPPPRPASRPKLASGKLSGINEIPRPFSPPVTSNTSPPPTAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAIALTESVNAYFKGADPTKCIVKITGDVTISFPSGIIKVFTSNPSPAVLCFRVKNISRLEQILPNSQLVFSDPSQCDSNTKDFWMNMQAVTIYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYLADC
What is the function of this protein?
Functions in an early step of clathrin-mediated endocytosis.  Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits.  Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane.  Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles.  Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
What are the official names of this protein?
F-BAR domain only protein 2.
What is the protein family that this protein belongs to?
Belongs to the FCHO family.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2.
Protein: Y361_HAEIN
Sequence: MDSFSTSIWVNDVTVRYNNGHTAIHNMTFSLNSGTICALVGVNGSGKSTLFKSIMGLVKPQQGEIKLCDLPISQALKRNLVAYVPQSEEVDWQFPVSVYDVVMMGRYGYMNFLRIPKAIDKQKVQEAMQRVNIEHLAHRQIGELSGGQKKRVFLARALAQQSPIILLDEPFTGVDVKTENAIVDLLQQLREEGHLILVSTHNLGSVPDFCDQVVMINRTVIAAGKTEDTFNQHNLEIVFGGVLRHIKLLGENLHNDEDKRSVTVLTDDEKAVVFYGETKQDPPAPTTQNCHFEDCPYKSAVKNKRD
What is the function of this protein?
Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable iron transport system ATP-binding protein HI_0361.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FDP_ARATH
Sequence: MLSSAKHNKINNHSAFSISSSSSSLSTSSSLGHNKSQVTMEEVWKEINLGSLHYHRQLNIGHEPMLKNQNPNNSIFQDFLNMPLNQPPPPPPPPSSSTIVTALYGSLPLPPPATVLSLNSGVGFEFLDTTENLLASNPRSFEESAKFGCLGKKRGQDSDDTRGDRRYKRMIKNRESAARSRARKQAYTNELELEIAHLQTENARLKIQQEQLKIAEATQNQVKKTLQRSSTAPF
What is the function of this protein?
Transcription factor required for the transition to flowering promoted by FT.
What are the official names of this protein?
bZIP transcription factor 27, AtbZIP27, Protein FD PARALOG.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP6_RICAE
Sequence: MTHSPLAQFDIKKLIDIKMFGFDVSFTNSSIYMLLASILALTYFYLAFYNRKLVPSRLQVSAEIVYNLVADMLNQNIGVKGRKFIPLIFSLFIFILFCNLLGMTPYSFTTTSHIIVTFTLAILVFLMVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIAGFTVSLMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYLNDVINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3F_CHAGB
Sequence: MAVEQEHFVHLARPLAPTSMGFTGSAPLTVHIQPQAVFSVIDHAVRRDTRDTQSTRVIGALVGTRSEDGSEVEVRSTFAIPHTENEDQVEVDVEYQKNMLALTLKASPRETLLGWYTTSHELNSFSALIQNFFASPETGTFPHPAVHLTISTEPGAPIATKAYISAPVAVSPERAAESCLFIEVPHKLLFSDAERAALGTATAAAETEARSAPVISDIETLAQSLESVSDLLERVSGFVGEVLDEERDGSHALGQYLMNALSLAPKVSATQIEADFNNHVQDVLMVSYLANTIRTQIDLAQRLATAPLVGGDKEGGEKGKDGEDGGRGGRGGKRGGGGRGGHRGEPREPREPREPAE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC72_HUMAN
Sequence: MSWDPNPVPRTLRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKAHIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRSVMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
What are the official names of this protein?
Leucine-rich repeat-containing protein 72.
Protein: GP6_BPMU
Sequence: MCIKAEKYIEWVKHCQCHGVPLTTYKCPGCGEQIMTQCSPEKEIRDSLTCCPWCSAVFFKQVKGAKVKASAVIQNQ
What are the official names of this protein?
Uncharacterized protein gp6, E5, Gene product 6, gp6.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: ATP8L_ASHGO
Sequence: MTPQIIPFFFMHQFTYGFLVILLTLLLLSYAFLSMILRLYLSRIYLSK
What are the official names of this protein?
Putative ATP synthase protein 8-like protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RM05_ACACA
Sequence: MRFYNRYNSSLKNYLLCSINSFNTNTLKIPLKPTLSAVFNTFRGERSLKFIKLYLMILYISNQKPFIKKVKFSYIKKKILKRFFISVSLNKKNSFNFFMYMLNFYNYFFHIYYQKCLKYNRFENSLILYIDNIQFFFKNYNKQNQKTQIKCQLNLRNSQASILFKYLNNMFLIKVKN
What are the official names of this protein?
60S ribosomal protein L5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: F16PA_SHELP
Sequence: MQTLAQHLSSQGIQAPLAQLLTTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDVITNDMLKEALTADSTVRGLASEEEDHIVEVGQSGDFLVCFDPLDGSSNIDINSLVGTIFSVLPAPSGELSEQSFLQPGRQQVAAGYVLYGPSTMLALTTGQGVQLFTLNPETNEYLLTNEAMSISKDTSEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHRVLSRGGLFTYPTDNKNPEKPYKLRLMYEANPMSFLVEQAGGKASTGYETIMDILPSEIHQRVAVILGSANEVDACLEYHGQDYSEEPSL
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REXO3_EMENI
Sequence: MFAPLGLFRDIPCPQREECSLIACLFSHRDLNSAPAAQDQVLEQKEPAKLPPKRLKLEPRPEAKETPKDDLRHVSDSGRSTPVKKTTAPATNAENISPVSRQPNIPKNTATAPIKRELNANTGSSIPPRRAPKEALNPRMIQKSPATYNVRMAILKKLHGTLCSLNDQLAKDKALEDKCLILTPDELITMALDEEEKVAKESPTVYSNVVKLRIVKLSRMSKEDWAKELKDYLNKKYYKIKAEPVQKEPKPFKTDLSVEEEIAVASQLITPLQGLEDFGYVTRVPTAEEIEIAKRGVAEAKGWEKCERCNARFQVFPGRREDGTLTSGGTCTYHPGKSFYPPRKKTDHITGTMREGYFTCCNQKLGESSGCTTGATHVYKVSETKRLASILQFEKTPENPDLHNPTPICFDCEMGYTTLGMELIRLTAVSWPEGKKVLDVLVRPLGEVLDLNSRFSGVFPEHYTNALPYSTAPTKSSAPSSSSPSQLQLVSSPAAARTLLFNLLTPSTPLIGHAIDNDLNACRIIHPTVIDTAILYPHPGGGLPYRMSLRTLAKKHLDREIQTGGASGKQGHDSVEDALATGDLVRVKAGLVWGRLKEKGWIVEEGRLVAPDSSSNTVSMQTKLGEGAGAKRAREGTS
What is the function of this protein?
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
What are the official names of this protein?
RNA exonuclease 3.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIBA_ECOLI
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: YR403_MIMIV
Sequence: MNKGQNQVVPPMSQFGGQNPPQLSSIPPIVNPVVVQNRTSPGTPFITNKAKEIYNRRQQEEISSDSEEEESPIEPAKSKYSRDSRDSRDTRDSRKPKKDSRNMLGSLQKTGTEIAYEPAVKFEMILPKVVKPTRPETPLGIYEQYTPILPPVNNNRFNPAAFQHLFAPSSALLYGQSVKMPMQNVYNINLPGPTGGHVAMDKIYENILPGKNVKCGFSTLGERIQMLDYIRQILVSSCDGENISIDSSGGNSLLSYIKLMELNPNFYSTITNNPYKGLPYGLLIYRSCFPIRFEPTNQSVVCAKNSIGLNIRLYALSYAEYYSYKLNNNIYLEYDVWRELMYYEYVKNRIIKSKQSPNFPILYAYFFCPNRNINFFQLKTNCLTRKELLSEEYKKFRQIHEAISNTGTNKIIRPMSMSGQNDKCQLPDEVDPLFRLYSGTTLILITEAPHHNLYQWASRTYETDGIVQRMTSSGFYDEKIWYDILFQIISALYVMQIHGIYIRNMTIEDNVYIKDLKISGKSCGYWKWIIDGIPYYVPNYGYLVMIDSNFKDTRSESSLLDRDCCEREYKIYANNIYSQKYDSNVLNENIFENYRRIINTNAFTKEHTKNNVMRPPESIMRLIELMSNDPEKNLGTVLHKYFRKYLNNRIGTLLRRDTEIPNVRDVTRQFNNGEMAVEVIGDQMYKWCMVSKTNSDGTVEIITRSDSNLDDYIIKDVRIETLKQYSPYENIDQNLDQEVKLDDNPLETYTISSN
What are the official names of this protein?
Uncharacterized protein R403.
What are the subcellular locations of this protein?
Virion.
Protein: TVA5_HUMAN
Sequence: MKTFAGFSFLFLWLQLDCMSRGEDVEQSLFLSVREGDSSVINCTYTDSSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLTVLLNKKDKHLSLRIADTQTGDSAIYFCAES
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 5.
What are the subcellular locations of this protein?
Cell membrane.