PharMolix/UniProtQA huggingface dataset:
Protein: FSCB_MOUSE
Sequence: MEECEEPEEPISLGRQEYRRRRRPSQPMVDKSQQTEITEKRKAMASVQPPAPKATHSIGNIPGSKDNYSRKEYESLRLSSQLQKTLMKRKHVQDMTDKSLQTEPIVEEKVEVIFIDKTLKLEENTAGVGEIAPELPQSIPEVEIPTSRPTSHLIDRSQQTSCTGDWSLIYICPKEKVDKEQQTYFSELEIIIRSIPGSSMTKSKEETIPIAQEDPLVEINGSLEIEVLSPEELPDVMMSFTEGEISGELQALSNGEATVKGELFLTEEIPIQAPSPAEETSAAETATTTAKDVVDIQAPPADKLSSVEAPADISPTLVQGALSDKPSDQQYPQGTEMAPSELPVEDLDPFSEEVLEKVQALTTDSMLEDLGIAESTIAEETSGKVQHPLSEETSKEVPAEVHFPIAADFEESAILINEKFATDEVFEEYKPPIIEEVSADKATAEVQPPSAEDASEEVASSEVLPPSTEQGTVEDLTAEVLSTPTEEGPTEVPPQPTEEGPAEVPPPLSEEGPAEVPPAPAEEAPAEVLPPPAEEAPAEVPPPLTEEGPAEVPPPLTEEGPAEVPLAPAEEVPAEFLPPPAEEVPAEVPPPLTEEGPAEVPPPLTEEGPEEVPPLPAEEAPTKVPPSPAEKGSAEVSPPQTEEGPAEVPPPPAEEFPTEVPSSSAEEGSSEVPLPPTAERPEEAPPPATEEAPVEVLPPATEEAPVEVLPPATEEAPVEVQSPAAEEGLAEVPPPPTEESPTHDVPTEVQVPQAKESPGQVLPLSGESTAEEASAQVQPPSFEKAPLESLPLEEVEKIHLDNLPFEVQPLPTEDIAIGVPAESQALPADENPAREDTVETQPSSFEGAPIAENPIEAPLPASEADTGREDSAVHPSSLGPTDEAPAEIQILQTDDIPTEMSPVENQPLPAEEGFPEVVSEEEATAAEVRFPLSEGAPAQEATVEAQLTSVEESPKRASVDVQPLSPETPVEESPGVDLPLKTNEVTMQEFRVEKMPAEDSLPPSEQTPADQVLLKEHRLSQVADISEKELESTTLTSDKMSEGIDSVPEDVSGTKDDQISTFKIEGTIKIELKN
What is the function of this protein?
May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation.  Inhibits ROPN1 and ROPN1L SUMOylation.  Binds calcium.
What are the official names of this protein?
Fibrous sheath CABYR-binding protein, PKA-phosphorylated calcium and CABYR-binding protein.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Localizes to cortex of the fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.
Protein: FOLM_ECOLI
Sequence: MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLADVLACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.
Protein: SYI_BARQU
Sequence: MTVKNETIDYSKTLYLPQTNFPMRGRLPQKELELIARWDNMGLYAQLRQQAKDRPLYILHDGPPYANGHIHIGHALNKVLKDVIIRSFQMRGFNANYVPGWDCHGLPIEWKIEEKYRAQGKNKDDVPLNEFRQECREFAKYWITVQSEEFKRLGVVGDFNSPYTTMAFHAEARIASELMKFAMSGQIYRGSKPVMWSVVERTALAEAEIEYHDYESEVIWVKFPVLQADSSDLCGAYVVIWTTTPWTIPGNRAVSYSSQISYGVYEVASTQNDFGPQVGERLLFADALAMSCAEKAKLVLKRLRIISADELKTLFLFHPLKGFAGSYNDKIAMLDGAHVTENAGTGFVHTAPSHGREDFEIWNAYKPLLEQFGIDSSIPFPVDDAGFYTKDAPGFGPNREGGAVRVIDDNGKMGDANKEVINALIKADRLFARGRLKHSYPHSWRSKKPVIFRNTPQWFISMDKDLGDGSTLRSRALEAVSMTRFVPSSGQSRLASMIADRPDWVLSRQRAWGVPICIFANEDGVILKDERVNERILRAFEAEGADAWFAEGARERFLGERAHESWVQVLDILDVWFDSGASHSFVLEDRDDLKWPADVYFEGSDQHRGWFQSSLLESCGTRACSPYKAVITHGFTLDENGKKMSKSLGNTVVPQEIIKTSGADIFRLWVMTTDYWEDQRLGKQILQTNMDLYRKLRNAIRWMLGILAHDEGEKISYCALPDLEKFILHQLFELDQLINRAYDEFDFKKIMRALLDFSITELSAFYFDIRKDSLYCDAPSSKKRKASLQVIREIFERMVIWLAPMLPFTMEEAWLEHSPKSHSVHLEQFRSVPGEWQNGFLAERWRKVRQVRKVVTGALEFERAAKRIGSSLEAAPIVFISNPVLLEALENLDMAEICITSALTITQDVPPSDAFILSDVEGVGVYPGKALGTKCARSWRYTQDVGSDPAYPDVSARDAAALRELQMLGKI
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYA_PAEAM
Sequence: MKKMLTLLLSAGLVASIFGVMPAAAAPTVVNSTIVVPKGTTYDGQGKTFVANPSTLGDGSQAENQKPVFRLEAGATLKNVIIGAPAADGVHCYGNCNISNVVWQDVGEDALTLKSSGTVNITGGAAYKAYDKVFQINAAGTINIKNFRADDIGKLVRQNGGTTFTVNMTLDNSNISNVKDAIMRTDSSSSQGRITNTRYSKVPTLFKGFASGKTSQSGNTQY
What is the function of this protein?
Catalyzes the depolymerization of both polygalacturonate and pectins with low (20-34%) and high (90%) levels of methyl esterification, with an endo mode of action.  In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.  Does not show xylanase and cellulase activity.
What are the official names of this protein?
Pectate lyase A, Pectin lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_ECO55
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAW1_RAT
Sequence: MKLKSLLLRYYPPGIMLEYEKGGELKTKSIDLLELSPSTDVNTLVGEIQKVEPLITASRTKQVRLLVQRLQEKLRQHCDHNFYLFKVLRAHILPLTNVALNKAGSCFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHTAEIVCLSFNPQSTVVATGSMDTTAKLWDIQSGEEVVTLTGHLAEIISLSFDTSGDRIITGSFDHTVVVWDASTGRKVHTLIGHCAEISSALFSWDCSLILTGSMDKTCMLWDATSGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARVYNATTRKCITKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDVQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNSCRIWR
What is the function of this protein?
May play a role in axonemal outer row dynein assembly.
What are the official names of this protein?
Dynein assembly factor with WDR repeat domains 1, Outer row dynein assembly protein 16 homolog, WD repeat-containing protein 69.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR69 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: PURA_STRGG
Sequence: MPALVLLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGDQKYALHLLPSGILSPGCTPVIGNGVVVDPAVLLSELSGLNERGVDTSKLLISGNAHLITPYNVTLDKVTERFLGKRKIGTTGRGIGPTYADKINRVGIRVQDLYDESILEQKVEAALEQKNQLLAKVFNRRAIEAGKVVEDMLQYAEQIKPFVADTTLILNDAIDEGKVVLFEGGQGTLLDVDHGTYPFVTSSNPTAGGACTGAGVGPTKISRVIGILKAYTTRVGAGPFPTELHDEDGEALRRIGGERGVTTGRDRRCGWFDAPIARYATRVNGLTDFFLTKLDVLTGWERIPVCVAYEIDGKRVEELPYNQTDFHHAKPIYENLPGWSEDITKAKTFSDLPKNAQAYVKALEEMSGAPISAIGVGPGRTETIEINSFL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_MYCLE
Sequence: MLLAIDVRNTHTVVGLLSGSKEHAKVVQQWRIRTESEVTADELALIIDGLIGDDSERLAGAAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHKFGQAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGVVFGFAGLVDGLVGRMRQDVEEFSGDLGNRVAVVATGHTAPLLLPELHTVDHYDRHLTLHGLRLVFERNREAQRGRLKTAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_OLEA2
Sequence: MTINPDDLCRRIMADPEACATEDEALRLLELPAEQTLPLIACAQRIRTAHAGPAFTCAIVNARSGRCPENCSFCAQSAHYATGAPEHPMLNTAALVEHALKLADAGADRFGIVTSGTRPAPRELETVCEAVVRIRARTHLSPCASLGQLSPQAAAMLRQAGLERYHHNLETARSFFASVCTTHDYDEDIYTVKLAREAGLAVCCGGILGLGESRAQRAELSGQIKRCRADSVPVNLLTPVAGTPLERMDPLPPFEALRTIAVFRFMHPQADILVAGGREHVLGEYRSWTFISGANGLMVGNYLTTAGRSTADDYTMLRHMGVLR
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TRPA_STRT2
Sequence: MTKTLTKHLQAIKDSKRGIFVPYIMAGDHAKGLDGLFETITLLENSGVSAIEVGIPWSDPVADGPIIELAGQRSLAKDVTLTAIIKKLQEKKTQVPLVIMTYINPVYQYGIEAFVKDLAETSVKGLIIPDLPNEHADFITPYLRDSDIALVPLVSLTTGIDRQKQLIDGAEGFIYAVAINGVTGKTGNYRDDLDKHLSNLTAYADIPVLTGFGVSTEEDIKRFNAVSDGVIVGSKIVRDLHDGKEEEVAEFVTFGSHFEK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TLP_PRUAV
Sequence: MMKTLVVVLSLSLTILSFGGAHAATISFKNNCPYMVWPGTLTSDQKPQLSTTGFELASQASFQLDTPVPWNGRFWARTGCSTDASGKFVCATADCASGQVMCNGNGAIPPATLAEFNIPAGGGQDFYDVSLVDGFNLPMSVTPQGGTGDCKTASCPANVNAVCPSELQKKGSDGSVVACLSACVKFGTPQYCCTPPQNTPETCPPTNYSEIFHNACPDAYSYAYDDKRGTFTCNGGPNYAITFCP
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Allergen Pru a 2, Beta-1,3-endoglucanase, Thaumatin-like protein, TLP.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KLHDB_DROSE
Sequence: MGDLPGSGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: ARI1_BOVIN
Sequence: MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED
What is the function of this protein?
E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3.  Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets.  The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2.  E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes.  Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear.  According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest.  According to another report EIF4E2 ubiquitination leads to its subsequent degradation.  Acts as the ligase involved in ISGylation of EIF4E2.  In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, may act in nuclear subcellular localization and nuclear morphology.
What are the official names of this protein?
E3 ubiquitin-protein ligase ARIH1, Protein ariadne-1 homolog, ARI-1, RING-type E3 ubiquitin transferase ARIH1.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Mainly cytoplasmic. Present in Lewy body.
Protein: TARI_STRA1
Sequence: MNIGVIFAGGVGRRMNTKGKPKQFLEVHGKPIIVHTIDIFQNTEAIDAVVVVCVSDWLDYMNNLVERFNLTKVKAVVAGGETGQMSIFKGLEAAEQLATDDAVVLIHDGVRPLINEEVINANIQSVKETGSAVTSVRAKETVVLVNDSSKISEVVDRTRSFIAKAPQSFYLSDILSIERDAISKGITDAIDSSTLMGMYNRELTIVEGPYENIKITTPDDFYMFKALYDARENEQIYGM
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: CID4_ARATH
Sequence: MSIPQSKSSSNGFPLKRGETEEVLHKTNTSNTVFNGEAGSLKRLSLDRLVYFTTCKIGHHVEVHLRNGSVYTGIFHAANVEKDFGIILKMACLIKDGTLRGHKSRSEFVRKPPSKTFIIPADELVQVIAKDLSVSSNNMSNAVQGEKPSELLTDSSISQSYHVDRERQLQRWVPDETIPHGADLENVFDNPWNRKWNQFEVNKSLFGVKSTFDEDLYTTRLERGPQTKQLEEHAQKIAREIEAETTRDIHVAEERGLQLNENFDFDEEARYSSVRPVTGFGDSGFDLEDNALLDTCNDLTFGGSSTSDGQKPASSGKGCEELRVSGDSQSSRKNKNVDQSCSTSKQQSKDFPAAGSNISESQLDEQRRKNNEEVSHNNRSAEESTSGHGDIKEGAKSGGGASSVSKAVTEREREASQVSSKTKSESSFGQSASRSSESRPGPSTSSRPGLSPSSSIGSMASSEKSTLNPNAKEFKLNPKAKSFKPLQSAAAPPQSPIADASFYYPGPSHVPVQQMPGMPPVNYGLPPYPGNQPQMMYHPQAYYHPNGQPQYPQQQMIPGQQQQQMIPGQQHPRPVYYMHPPPYPQDMPYHNKGRE
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 4, PABP-interacting protein 4, Poly(A)-binding protein-interacting protein 4, PAM2-containing protein CID4, Protein CTC-INTERACTING DOMAIN 4.
Protein: QUEA_SHIF8
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PHEZH
Sequence: MALSPRDTTKRRAQRVRTRLRKVANGRPRLSVFRSAKNIYAQVIDDERGVTLAAASSLEGEKKDKGSDKDAAARVGALVAQRAIEKGVKDVVFDRGGYLYHGRVKALADAAREAGLNF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: XERD_SALTY
Sequence: MEQDLARIEQFLDALWLERNLAENTLSAYRRDLSMVVAWLHHRGKTLATAQADDLQTLLAERVEGGYKATSSARLLSAMRRFFQHLYREKYREDDPSAQLASPKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDISLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQMTRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerD specifically exchanges the bottom DNA strands (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_CHLT2
Sequence: MSRLKKLYTEEIRKTLQDKFQYENVMQIPVLKKIVISMGLAEAAKDKNLFQAHLEELAVISGQKPLVTRAKNSIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSCKGDGRGCYSLGLDDQQIFPEVDLDRVKRSQGMNITWVTTAQTDAECLTLLECMGLRFKKAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TAUB_CHRVO
Sequence: MAALTADRVSVRYPGQAQPALDGVSLNVGPGELAVALGPSGCGKTTLLNLFAGFQFPDSGSVRFGGVPVAGPGAERAVVFQQHALLPWLSALDNVAFGLRLRGVPRAERRELAGRALAQVDLAEAGARYPWQLSGGQKQRVGIARALAGRAGALLMDEPFGALDAFTREQMQELLLKVWAESGSSVFLITHDIEEALFLATELVLMSPGPGRIVKTLRPPFSRRWRAGDSARAIKSDPEFIALREQLLADVFAQRKQEAWA
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECX_STAAE
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBG_RABIT
Sequence: ADPPGGDISTRSPPRGLAPANVDFAFSLYRQLVSSAPDRNICISPVSVSMALAMLSLGASGHTRTQLLQGLGFNLTEMPEAEIHQGFQYLHHLLGESDTSLEMTMGNALFLDHSLELLESFSADIRRYYESEALATDFQDWPRACRQINEYIENKTQGKIADLFLGLENPAILILVNYIFFKGTWAHPFDPQSTEEKSFYVDDTTTVMVPMMFQSSTVKYLHDPVLPCRLVQLDYVGNGTAFFILPDKGKVDTVIAALSRDTIQRWSKSLTYRLVHLYIPKASISGAYELRGALAAMGIADLFTNQANFSSISQEGPLKVSKVLHKAVLQLDEHGGVEVAATGGPLQLVSEPLTLNFNRPFLILIFDDFTWSSLFLGKVVIPA
What is the function of this protein?
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
What are the official names of this protein?
Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: H16M1_CYRHA
Sequence: MNTVRGTFLLVFGLAASLGQADKNENRREMQKKTEQGKSYLNFAENLLLQKLEELEAKLLEKHSKKSKNSRQKRCIGKDVPCDENDPRCCSGLICLTPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1m, U11-TRTX-Hhn1m, Hainantoxin-XVI-13, HNTX-XVI-13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_MESM1
Sequence: MSAIMRIHAREVLDSRGNPTIQIEVESEYGYGSAMVPSGASTGEKEAKELRDKGTKYEKNWYGGKGVQTAVDNVNNIIAPKIEGYDVLDQRAIDYEMIKLDGTEFKEKLGANAILGVSLAVAKAAADELNIPLYRYVGGTNGFKLPVPMLNVINGGEHASNTVDFQEFLIMPIGAKTFKEAMQVANKVFHNLKDLLASQGHSTAVGDEGGFAPDLKSHEEVLDFIVSAIKKAGYEPSKKGDKAVAIAIDAASSELFDKKSKTYTFKKLKKAILTKQPGFENLGKVKVEYSSDELVEYFKDLFKKYPIISLEDGFSEHDWDAFTKLNNSVGATHQIMGDDLVTTNPKFIKKAIETKAINSVLIKLNQIGTLSETMDAIEMAHKAGMTCVVSHRSGETEDTTIADLAVALNTGQIKTGSISRTDRVAKYNRLLVIEEELGIVASYEGIQVFHNLKVK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: LCPS_GIBFU
Sequence: MGWEYAQVHLKYTIPFGVVLAAVYRPLMSRLDVFKLVFLITVSFFWVVKGLEANSCRLLLFLPCMLILRGVLLRLTNADSPWDSYLIKNRIWTYPPGVVVGLTAWDIPAEELFFFVIQTFNTSLLYMILSKPTFHPIYLSKKTGWGKIAGQILFASAIIFGLVSVSSGGEGMYMGLILIWACPFLLFLWSISYQFIVNLPWTNTALPIALPTLYLWVVDTFALRRGTWSITSGTKYGVVLWDGLEIEEAVFFLLTNTLIVFGLIACDNNLAILDTFPEHFPRTKGVPSLLTIIRTLILPKEKYDEERIQGLVSAVALLRKKSRSFYLASGTFEGRLRIDLIRLYAFCRAADDLVDEAPSVDDSRASIEKLRKFLDLAYEENQEEPSQRLREYVTSSIPEMFHMALLQLPTYYLPKQPLDDLLKGFDTDLLFDRKSGAFPIETTEDLDIYGSRVAGTVAELCNHLILYHTPEAVPEDIQREVVASGQEMGIALQYVNIARDIKTDAEIDRVYLPLSWLKEAQLTPEDVIQQPHGPTIEALRHKLLDRAFEKYNMAKGAIDKLPSEGKGPIRVAVESYMEIGRVLREKGPTMKKGRATVPKMRRIRVAWSALNK
What is the function of this protein?
Bifunctional enzyme; part of the car gene cluster that mediates the biosynthesis of neurosporaxanthin, a carboxylic apocarotenoid acting as an essential protective pigments and leading to orange pigmentation (PubMed:12172798).  CarAR catalyzes the first step of the pathway by converting geranylgeranyl diphosphate to phytoene, as well as the later cyclization step that transforms the carB product lycopene into gamma-carotene (PubMed:12172798).  CarAR also converts part of gamma-carotene into beta-carotene (PubMed:12172798).  Neurosporaxanthin is synthesized from geranyl-geranyl pyrophosphate (GGPP) through several enzymatic activities.  Phytoene synthase activity performed by the bifunctional enzyme carAR first produces phytoene from geranyl-geranyl pyrophosphate (GGPP).  The phytoene dehydrogenase carB then introduces 4 desaturations to lead to lycopene which is substrate of the carotene cyclase activity of carAR that leads to the production of gamma-carotene.  CarB then performs a 5th desaturation reaction to yield torulene.  Torulene is the substrate of the dioxidase carT that breaks the molecule, removing five carbon atoms to yield beta-apo-4'-carotenal, whereas the aldehyde dehydrogenase carD mediates the last step by converting beta-apo-4'-carotenal into neurosporaxanthin (Probable).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.