PharMolix/UniProtQA huggingface dataset:
Protein: NAGB_PSET1
Sequence: MQVLIFDDKKAVAENAATLLQKLILAKNNANIGLATGSTPIDLYKQLVSMYKNKHISFAQVNTFNLDEYYDIDENNSNSYRYFMNSQLFDHIDIDKNNTHLPTCNAKQDPRKQGEHFEQQIAALGGLDLQLLGIGGNGHIGFNEPSSSFASRTRIKSLTEQTVSDNSRMFSDDEQQPKMAMTMGIATIMDAKYVLLIATGKNKAQAVNDMVNGPLSASCPASILQMHKNAIVIIDNDAASLLANKDYFTWVSQQNHEINQAFGHFPDL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: HXD10_CHICK
Sequence: FLIEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D10, Chox-4D, Homeobox protein Hox-4.5, Chox-4.5.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APC5_MOUSE
Sequence: MMTNGVVHANLFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMDREDGEKQMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLNAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKDRFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAVLDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLSEAKNYFAQVDCRERIRDVAYFQARLYHALGKTQERNHCAMIFRQLHQELPAHGVPLINHL
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5.
What is the protein family that this protein belongs to?
Belongs to the APC5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: RS11_ECODH
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RAP1A_RAT
Sequence: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL
What is the function of this protein?
Induces morphological reversion of a cell line transformed by a Ras oncogene.  Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.  Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (By similarity).  Plays a role in nerve growth factor (NGF)-induced neurite outgrowth.  Plays a role in the regulation of embryonic blood vessel formation.  Involved in the establishment of basal endothelial barrier function.  May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
What are the official names of this protein?
Ras-related protein Rap-1A, Ras-related protein Krev-1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm, perinuclear region. Early endosome. Late endosome. Cytoplasm. Cell junction. Note=Localized with RAPGEF2 at cell-cell junctions. Colocalized with RAPGEF2 in the perinuclear region (By similarity). Recruited from early endosome to late endosome compartment after nerve growth factor (NGF) stimulation.
Protein: KAB3_OLDAF
Sequence: MAKFTKSLVLCLLLAAFVGAFGAELSEADKANVVNEIAANIQREILKGVKSSETTLTMFLKEMQLKGLPTCGETCFGGTCNTPGCSCSSWPICTRNGLPKRAGVKSSETTLTMFLKEMQLKGLPTCGETCFGGTCNTPGCTCDPWPICTRDGLPSAAA
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has hemolytic activity.
What are the official names of this protein?
Kalata-B3/B6.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: ALD1_STAES
Sequence: MRNFTKQYINGEWVDSASGETIDVINPATEEVMGKIAKGNEEDVNKAVDAADKVYLEFRHSSVEERRELLDKIVKEYQNRKNDLIEAITDELGAPLSVSENVHYQMGLNHFTAARDALDSFQFEEQRGDDLVVKEAIGVAGLVTPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFAAIILAEIFDKVGVPKGVFNLVNGDGSGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDVEEAANATTKKVVNNTGQVCTAGTRVLIPESIKEDYLTAVKEAFSKVKVGQPREEGTQVGPIISKKQFDQVQDYIDKGINEGAELFYGGPGKPEGLDKGYFARPTIFINVDNHMTIAQEEIFGPVMSVITYNNLDEAIEIANDTKYGLAGYVIGKDKDTLRHVARSIEAGTIEINEAGRKPDLPFGGYKESGLGREWGDYGIEEFLEVKSIAGYFK
What are the official names of this protein?
Putative aldehyde dehydrogenase SE_1720.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CLPX_SYNC1
Sequence: MSDHDGKSGYLTCSFCGKGQDDVKKLIAGPEVYICDECIELCKDIIAEEAKLEDDAESGPKRLPRPSEIKDALDEYVIGQEKAKKILSVAVYNHYKRVEMVQDGDDIEIQKSNILMLGPTGSGKTLLAQTLAKLLNVPFAIADATNLTEAGYVGEDVENIILSLLQAADYDLEKAQRGIIYIDEVDKIARKSDSPSITRDVSGEGVQQALLKIIEGTTASVPPKGGRKHPQQEFLKVDTTNILFICGGAFSGLESVIKQRSGTKALGFGAEIKEKKEEGVGEILARTEPMDLIRFGLIPEFVGRLPVVATLEELDEESLVRILKEPKNALVKQYQKLFEMEKVHLKFTDGALVAVAAEALKRKTGARGLRSIIENAMLDVMYDIPSQDRVKEVVINEDVIRQQGKPIIVYDCAESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RS8_METS5
Sequence: MTVINTLSNALSSLYNNEMRRNKQAIIMPSSKLIVNVLRVMQKEGYVGEFEYIDDGRWGKILVQLMGRINKCGAITPRYSLTYREMISLPDYIRRYLPSKEIGVIIVSTPKGVMTHKEAARQRTGGIVLGYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYY_XANP2
Sequence: MTTQTFRSDFLRTLHERGYIHQCSDLERLDAKAAEGPITAYIGFDATASSLHAGHLLSIMMLRTLQRTGHNPIALMGGGTTKIGDPSGKDEARKMLTDQQIEDNIASIRKVFARFLDFGAGAKMENNASWLDELKYIPLLREVGPHFTINRMLTFDSVKLRLEREQPLTFLEFNYMILQAYDFVELNARHGCILQMGGSDQWGNIVNGMELGRRMRGADLFALTTPLLTTSSGAKMGKTAGGAVWLDADLLSPYEYWQYWRNAGDADVERFLKLFTELPLDEIARLAALEGQEINHAKEVLATEATALLHGREAAEKAKETSRATFADGALAVDLPTVEVPRATLEAGLPVAKAFVDAGLVASTSEARRQIKGGGLKVNDVTVTDEKAVIDLGALTPEGVVKLSLGKKKHVLLKPV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_BRUAB
Sequence: MFRAIAIIRAHEVIDAVPASHIVLERDERHLRRKAITLENGEKILADFAEPVVLEHGDRLVLDDGREIEIRAASEELYEIRGRDPRHIAELAWHIGNRHLAAQIETDHIFILRDHVIRVMLEGLGATVTDVVAIFSPLRGAYSGGHQHHHGHDHDHGHHGHDHDHHHPDHE
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDS_TARER
Sequence: MATSSTSSTTSLCFPATSAAGARTSFRTTDTFLRYRRSRQLTRLKVRKAVVRSDLDRDVSDMRTNAPKGLFPPEPEHYRGPKLKVAIIGAGLAGMSTAVELLDQGHEVDIYESRTFIGGKVGSFVDKQGNHIEMGLHVFFGCYNNLFRLLKKVGAEKNLLVKDHTHTFVNRGGELGELDFRFPVGAPLHGINAFLTTNQLKTYDKARNAVALALSPVVRALVDPDGAMTQIRNLDNISFSEWFMSKGGTRTSIQRMWDPVAYALGFIDCDNISARCMLTIFSLFATKTEASLLRMLKGSPDVYLSGPIRDYIIEKGGRFHLRWGCREILYEKSANGETYVTGLAMSKATQKQIVKADVYIAACDVPGIKRLLPSNWREWEFFDNIYKLVGVPVVTVQLRYNGWVTELQDVERSRQLRQAAGLDNLLYTPDADFSCFADLALASPEDYYIEGQGSLLQCVLTPGDPYMPLPNEEIISRVSKQVLALFPSSQGLEVTWSSVVKIGQSLYREGPGKDPFRPDQKTPVKNFFLAGSYTKQDYIDSMEGATLSGRQASAFICDAGEELAALRKQLAAIQSIDSIGVDEMSLV
What is the function of this protein?
Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene.  It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' (By similarity).
What are the official names of this protein?
Zeta-carotene desaturase, chloroplastic/chromoplastic, 9,9'-di-cis-zeta-carotene desaturase, Carotene 7,8-desaturase.
What is the protein family that this protein belongs to?
Belongs to the zeta carotene desaturase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, chromoplast.
Protein: YPEB_ECOLI
Sequence: MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAGKLGELMQITLLIKTEGLTQLVQPLKRPL
What are the official names of this protein?
Uncharacterized protein YpeB.
Protein: RBFA_HALOH
Sequence: MKRQRARRLGELLKKEISDIILREVKDPRIGFISVTDVEVSNDLRHAKVFVSVYGDEKERKETMEGLEKATGYIRKLIGERVKVYYTPEILFRYDDSLEHGARINELLKKVKEEEESDREEG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESMD_DROME
Sequence: MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEIIDMAEEPVNLADQKRSKSPREEDIHHGEEVWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity).  May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes (PubMed:1528887).  Contributes to the neural-epidermal lineage decision during early neurogenesis (PubMed:1427040).  As part of the Notch signaling pathway, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm (PubMed:28899667).
What are the official names of this protein?
Enhancer of split mdelta protein, E(spl)mdelta, HLH-mdelta, Split locus enhancer protein mC.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y106_ENCCU
Sequence: MRSISVGLDREESGSDGLCLGLVVLATLAAGFVAGSDVLRCWGFGPATGDVCLWVEAGFWRCPLPGGGADGQGPGFWDAALREARMFCRSCVGLRMIGWRR
What are the official names of this protein?
Uncharacterized protein ECU01_0060/ECU01_1550/ECU02_1580/ECU04_0070/ ECU08_2110.
Protein: YGEA_ECOLI
Sequence: MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVDFHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFLHIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQIIFEELCLGQFTEASRAYCAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAAIHAEDAVAFMLS
What is the function of this protein?
Amino-acid racemase able to utilize a broad range of substrates.  Highest activity is observed with L-homoserine and D-homoserine.  Has tenfold lower activity against L-methionine, L-leucine, L-valine and L-histidine.  Has low activity with L-norvaline, L-asparagine, D-methionine, L-aminobutyric acid, L-isoleucine, L-serine, L-norleucine, L-alanine, L-glutamine, LL-diaminopimelic acid and L-phenylalanine.  Has no activity against ten L-amino acids (Thr, Glu, Asp, Arg, Lys, Tyr, Trp, Orn, Cit and Aad) (PubMed:28894939).  D-amino acids might be used as components of peptidoglycan and/or be involved in peptidoglycan metabolism and remodeling (PubMed:28894939).
What are the official names of this protein?
Broad specificity amino-acid racemase YgeA.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y3527_KLEP7
Sequence: MAQVPAGKNRSGQLSKQTGDAWENQARRWLEGQGLRFIAANARERGGEIDLIMRDGTVTVFIEVRYRRSARYGDAAASVTPQKQQRLLKAARLWLCRQNGSFETVDCRFDVVAFTGNDIQWLKNAFGE
What are the official names of this protein?
UPF0102 protein KPN78578_35270.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: IF4A3_ARATH
Sequence: MAGMASDGTQYDPRQFDTKMNAILGEEGEETFYTNYDEVCDSFDAMELQPDLLRGIYAYGFEKPSAIQQRGIIPFCKGLDVIQQAQSGTGKTATFCSGVLQQLDISLVQCQALVLAPTRELAQQIEKVMRALGDYLGVKAQACVGGTSVREDQRVLQSGVHVVVGTPGRVFDLLRRQSLRADAIKMFVLDEADEMLSRGFKDQIYDIFQLLPSKVQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRSGRFGRKGVAINFMTSEDERMMADIQRFYNVVVEELPSNVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-3, eIF-4A-3, ATP-dependent RNA helicase eIF4A-3, DEAD-box ATP-dependent RNA helicase 23.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_SALTY
Sequence: MSNVCIIAWVYGRVQGVGFRYTTQHEAQRLGLTGYAKNMDDGSVEVVACGDAAQVEKLIKWLKEGGPRSARVDKILTEPHSPRETLTGFSIRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: DGOD_SALPB
Sequence: MKITHITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHEFADYLIGKDPARINDLWQVMYRAGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIEKLRGIGFDTFKLNGCEEMGVIDNSRAVDAAVNTVAQIREAFGSEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSRFEFKRVLDAGGLAILQPDLSHAGGITECYKIAGMAEAYDVALAPHCPLGPIALAACLHIDFVSRNAVFQEQSMGIHYNKGAELLDFVKNKEDFSMDGGFFKPLTKPGLGVDIDEARVIELSKSAPDWRNPLWRHADGSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: RUTD_ECOL5
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSRHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: TRMD_SALTI
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQAEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_RICRO
Sequence: MLKFLSEIGPVIAFFAGFFYGGGIQHATLYMLITSVICITLCYVIDKKVSKLSIISTTVLLVSGSITLISGDSMYIKIKPTILYVIFGIIFLMSGIRKNPFIKYALESIVRLKEESWITLSYRTAAFFFFMAVVNEVVWRNCSDETWVKFKVFGVIPITFIFILLQLPLLLKNKLPDSKI
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YGFZ_VIBCM
Sequence: MDWQNRFSVLNLSSHDPLPELMLTHLTGWGAITLVGADKKAYLQGQVTCNVVSLQEQQVTFGAHCDAKGKVWSVFRLFHHHDGYAMFQPQSAMEVELRELKKYAIFSKVTIAESSDIALGVMGSQADAWIDTVSETTGDVRRIAGGTAVRMSPQRWLLLVNAEQAEQYVNAWQGLHVEQSLWTRMDIEEAVPVVTQTAQNEHIPQALNVQAVDGISFTKGCYTGQETVARAKYRGINKRAMYIVKGNLSAPLSQDEPVVLERAVGENWRSAGALLTHYRFTDSIAIGLIVLPNDLEHDVKLRLAAQPDTRWHIQPLPYSLSDE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITA5_BOVIN
Sequence: CGEENICVPDLQLEVFGEQNHVYLGDKNSLNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDIKKTIQFDFQILSKNLNNVQSDVVSFRLSVEAQAQVSLNGVSKPEAVLFPMSDWHPQDQPQEEGDVGPAVHHVYELINLGPSSISQGVLELSCPHALDGQQLLYVTRVTGLSNCTTSHPPNPEGLELDPEGSQHHRLQRRMFLGRSPASSGPQILKCPEAECFKLRCELGPLHRQESRSLQLHFRVWAKAFLQREHQPFSLQCEAVYEALKMPYKILPRQLPQKALQVATAVQWIKAEGSHGVPLWIIILAILIGLLLLGLLIYILYNLFFFK
What is the function of this protein?
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen.  It recognizes the sequence R-G-D in its ligands.  ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.  ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.  ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling.  ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (By similarity).
What are the official names of this protein?
Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.
Protein: RLMC_YERPY
Sequence: MHCAQYAAGRCRSCQWLDKPYPQQLADKQHHLESLLAGHAVTQWLALVFGRESAFRNKAKMVVSGSVERPLLGMLHRDGTPVDLCACPLYPPSFEPVFTVLKTFIARAGLTPYNVARKRGELKFLLLTESTYNGELMLRFVLRSETKLAQLTAALPWLQQQLPQLAVISANIQPVHMAILEGEREIPLTEQQALPERFNQVPLYIRPQSFFQTNPPVAASLYATARQWVQEHEVHSMWDLFCGVGGFGLHCAGPETQLTGIEISAEAIACARQSAEQLGLKNVSFAALDSTRFATAEAQIPELVLVNPPRRGIGRELCDYLSQMAPKFILYSSCNAETMAKDISLLAGYHIERVQLFDMFPHTSHYEVLTLLALRR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: NIFZ_AZOVI
Sequence: MLPQFEYGDEVRLIRNVRNDGTYPGMNTGALLMRRGAVGCVYDVGTYLQDQLIYRVHFLDEGRTIGCREEELILASAPWIPNLFEFRDDVIATRSLAVRGQVLVKRGQLGSIMKVLRDEPELGIQYHVHFGDGLVLQVPEQSLAMADSTAAIEEVLDGI
What are the official names of this protein?
Protein NifZ.
What is the protein family that this protein belongs to?
Belongs to the NifZ family.
Protein: RR14C_SCHPO
Sequence: METTEGKNDLRAKLAEKIQTFRSQRKATEKVDRALLLQRRKEKAKARAEAKKLAKKESKAKQESKVAAYDTGNSSDNIADEENDNHKSTITYGTLIVGDDKFSNGKLKVAGKKRGPTDVFGALKHLEAKKRRIESMDEEKRRKIEESDKWHRVLLQAEGKKLKDNEQLLKKSIRRKEKEKKKSSDAWKERKDNEKKAMLMRQQRREENLKKRRESKKSKKGKAPKKKKPSKKK
What is the function of this protein?
Involved in ribosome biogenesis and cell polarity.  Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis (By similarity).
What are the official names of this protein?
Ribosomal RNA-processing protein 14-C, Ribosome biogenesis protein rrp14-C.
What is the protein family that this protein belongs to?
Belongs to the SURF6 family.
Protein: LPXD_GEODF
Sequence: MGKTLKEVAEYLGGRVIGDENAVVGGLGTLDDAGEGQITFLANPKYAQKVATTRATAVILPPGAPGHGRNVIEVSNPYLAFAKLLTLFYVAPPKALGVMDGAVIGQGVAMGKDISIYPGAHVADGVKMGDRVTLYPGVVLYPGVELGSDVTLHANVVVRERCRIGNRVTVHSGTVIGTDGFGYAPDGKDWYKIPQIGIVILEDDVEIGSNAVIDRAALEATIIGRGTKIDNLVQIAHNCVIGENCMIVSQVGISGSTKVGNHVTMGGQVGVAGHIQIGDNVMVGAKSGVPGNIPANQIVSGIPAFAHRDWLKASSVFPRLPEHRKTLASLEKRVQELEEKLKADEKVK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y1051_SHESR
Sequence: MLNTKFDELMEFPCAFPFKVVGDAHEALTDRVVAVVQRHAPGDYSPTVKASSKGSYYSVTIRVTVTSKDHIETLYTELAGIEGVRRVL
What are the official names of this protein?
UPF0250 protein Shewmr7_1051.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.