PharMolix/UniProtQA huggingface dataset:
Protein: URK_BACAA
Sequence: MGTNKPVVIGIAGGSGSGKTSVTKAIFDHFKGHSILILEQDYYYKDQSHLPMEERLKTNYDHPLAFDNDLLIEHLQQLLAYKQVDKPVYDYTLHTRSEEIIPVEPKDVIILEGILILEDPRLCELMDIKLFVDTDADLRILRRMQRDIKERGRTMDSVIDQYVNVVRPMHNQFIEPSKKFADIIIPEGGQNHVAIDSMVTKIATILEQKVNL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNC5D_RAT
Sequence: MGTGAADRSRGARWWLPWLGLCFWAAGAEAARGADSGEVLPDSIPSAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTALCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSHSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNPAMHPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSGTFPHGNNRGFSTIHPRNKTPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMLVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWSSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQQDGDLDSLACALEEIGRTHTKLSNITEPQLDDTDFNYSRQNGL
What is the function of this protein?
Receptor for the netrin NTN4 that promotes neuronal cell survival.  Plays a role in cell-cell adhesion and cell guidance.  Receptor for netrin involved in cell migration.  Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.  May play a role in apoptosis in response to DNA damage.  It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).  Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).
What are the official names of this protein?
Netrin receptor UNC5D, Protein unc-5 homolog D.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
Protein: Y15_BPT7
Sequence: MMYLMPLLIVIVGCLALHCSDDDMPDGHA
What are the official names of this protein?
Protein 1.5, Gene product 1.5, Gp1.5.
Protein: COBT_PSEMY
Sequence: MKLQWWQGPCQPLDHVARTKAESRQQQLTKPAGSLGRLEKLAIHLAALQGRERPSLDKLWIAIFAGDHGVVAEGVSAYPQAVTGQMLANFVSGGAAISVLARELDAALEVIDLGTAEPLPPLPGVRHLYVGAGTQNLAREPAMTLSQLLICLEAGRDSLLRARAVGCDLFVGGEMGIGNTTAAAALACWLLGCPASELAGPGTGLDGAGVAHKARVIDAALALHHAQIDGPLQALVHLGGFEIAALTGAYLAAAQQGIAVLVDGFICSVAALLAVRLNPGCRDWLLFAHHGAEPGHVRVLQALGAEPLLELGLRLGEGSGAALAVPLLRLACSLHGQMATFAEAAVAQRPQ
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: ANGL7_HUMAN
Sequence: MLKKPLSAVTWLCIFIVAFVSHPAWLQKLSKHKTPAQPQLKAANCCEEVKELKAQVANLSSLLSELNKKQERDWVSVVMQVMELESNSKRMESRLTDAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNEHIHRLSRQPTRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSTYSLKRVEMKIRPEDFKP
What is the function of this protein?
Has a role in the formation and organization of the extracellular matrix.  In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193).  Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).
What are the official names of this protein?
Angiopoietin-related protein 7, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein.
What are the subcellular locations of this protein?
Secreted.
Protein: HCAD_ECO5E
Sequence: MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDEQHLPYERPPLSKSMLLEDSPQLQSVLPAHWWQENNVHLHSGVTIKTLGRDTRELVLANGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKVELTLQSGETLQADVVIYGIGISANDQLAREANLDTTNGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNHAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRSIRKWIQSGKTFDAKQLTDENIALKSL
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: TETR4_ECOLX
Sequence: MARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLREALQIMDSDDGEQAFLHGLESLIRGFEVQLTALLQIVGGDKLIIPFC
What is the function of this protein?
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA.  Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
What are the official names of this protein?
Tetracycline repressor protein class D.
Protein: RSDA_MYCTU
Sequence: MREFGNPLGDRPPLDELARTDLLLDALAEREEVDFADPRDDALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRRRARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFNRSRVSDDQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVGNSWTPLAPVVEPPTPPTPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigD.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.  Neither S1P nor S2P proteases have been so far identified for this anti-sigma factor.
What are the official names of this protein?
Anti-sigma-D factor RsdA, Regulator of SigD, Sigma-D anti-sigma factor RsdA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: E1B55_ADECC
Sequence: MEQDSDLESGRATNQRPPRVRVRGAGVRGRGRVRRRALSEGQRRSPFRLDDLQLPDSLYVTRALQRDHALEMPRGQVDFSLIEAEERRAGPTDEWYFESVKTYRAKPGDDLQTLIKNYAKISLECGAVYEINSKIVVTGACYIIGNCAVLRANLPVGTAMFEVLNVDVIPSIGFMERIVFSNILFDCRSTTAVVCCISERNTLFHNCVFSGPHMLCLDIRAGAEVRGCHFVGAVCALRSKGLYSVRVRNSIFEKCAFGVVSGSKASISHSMFKDCACCIMFGGQGTIAHSHFMATTCTDTPMNLQLCTCEGNGSHVVPLGNIHFASNREAPWPTFNANVLVRVRLYMGRRRGVFHPKQSTFSMCVIAAPRGVVQRIYLFSVYDATCAILQLGEAGDAATERLCTRGMRHNTPSLRAAYVTDTRIDREINSQDTAEFFSSDEDNL
What is the function of this protein?
Plays a major role to prevent cellular inhibition of viral genome replication.  Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E4orf6.  This viral RING-type ligase ubiquitinates cellular substrates and targets them to proteasomal degradation: TP53/p53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.  Degradation of host TP53/p53 activity is essential for preventing E1A-induced TP53 accumulation that would otherwise lead to cell apoptosis and growth arrest.  E1B-55K also inactivates TP53 transcription-factor activity by binding its transactivation domain.  E1B-55K also functions as a SUMO1 E3 ligase for TP53 which causes the latter to be sequestered in promyelocytic leukemia (PML) nuclear bodies thereby contributing to maximal inhibition of TP53 function.
What are the official names of this protein?
E1B 55 kDa protein, E1B-55K, E1B protein, large T-antigen, E1B-495R.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 55 kDa protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Colocalizes with host TP53 to host PML nuclear bodies. PML localization of E1B-55K is necessary for E1B-55K-dependent SUMOylation of TP53.
Protein: CALC2_ONCGO
Sequence: CSNLSTCVLGKLSQDLHKLQTFPRTNTGAGVP
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin-2.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNTP_CAMJD
Sequence: MDFYSLIFLSCALGMDAFAVSLCKSFSVKKLHLKHYLIVGIYFGGFQALMPTIGYFIGITFASFIASIDHWIAFILLSLIGLKMIKESLENENCNSNAKQFGFKTMLALAIATSIDALAVGVSFAFLNVNLLLAIFLIGIITFILCIIALKIGNKFGIYLKNKAELLGGLVLIILGVKILIEHLFFD
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KHSE_NEIMA
Sequence: MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAAPVARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLSQDDAALLRAEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWARTADNKLDEALKKAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNLLLSLG
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RBFA_CORU7
Sequence: MADNARAARMAKRIQQIVAVAIEREIKDPRLEYVTITDTRMTGDLHDASVFYTVRGASIDEEPDVPLAAAALESAKGQLRKIVGDQLSVRFTPTLSFVHDTVPEASAHMEKLLAEARAKDEAVRAQAAQAKPAGEANPYKERN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTLL1_HUMAN
Sequence: MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK
What is the function of this protein?
Catalytic subunit of a polyglutamylase complex which modifies tubulin, generating side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin (PubMed:34782749).  Probably involved in the side-chain elongation step of the polyglutamylation reaction rather than the initiation step.  Modifies both alpha- and beta-tubulins with a preference for the alpha-tail.  Unlike most polyglutamylases of the tubulin--tyrosine ligase family, only displays a catalytic activity when in complex with other proteins as it is most likely lacking domains important for autonomous activity.  Part of the neuronal tubulin polyglutamylase complex.  Mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility.  Involved in respiratory motile cilia function through the regulation of beating asymmetry.  Essential for sperm flagella biogenesis, motility and male fertility.  Involved in KLF4 glutamylation which impedes its ubiquitination, thereby leading to somatic cell reprogramming, pluripotency maintenance and embryogenesis.
What are the official names of this protein?
Polyglutamylase complex subunit TTLL1, Tubulin polyglutamylase TTLL1, Tubulin polyglutamylase complex subunit 3, PGs3, Tubulin--tyrosine ligase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the tubulin polyglutamylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
Protein: CYAY_NEIG1
Sequence: MMTESEFIRASEALFEHIEDQIDENGWDFDCRFAGNVLTIEAGDGTQIIVNRHTPNQELWIAAKSGGYHFAEQNGKWLATRDSRDFYDVLNEALSAASGEAVEIAEL
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ASPA_PSEFL
Sequence: MISVMSSAASFRTEKDLLGVLEVPAQAYYGIQTLRAVNNFRLSGVPISHYPKLVVGLAMVKQAAADANRELGQLSERKHAAISEACARLIRGDFHEEFVVDMIQGGAGTSTNMNANEVIANIALEAMGHQKGEYQYLHPNNDVNMAQSTNDAYPTAIRLGLLLGHDALLASLDSLIQAFAAKGAEFSHVLKMGRTQLQDAVPMTLGQEFRAFATTLGEDLARLKTLAPELLTEVNLGGTAIGTGINADPRYQALAVQRLATISGQPLVPAADLIEATSDMGAFVLFSGMLKRTAVKLSKICNDLRLLSSGPRTGINEINLPARQPGSSIMPGKVNPVIPEAVNQVAFQVIGNDLALTMAAEGGQLQLNVMEPLIAFKIFDSIRLLQRAMDMLREHCIVGITANEARCRELVEHSIGLVTALNPYIGYENATRIARIALESGRGVLELVREEGLLDDAMLDDILRPENMIAPRLVPLKA
What are the official names of this protein?
Aspartate ammonia-lyase, Aspartase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
Protein: YPEL5_PONAB
Sequence: MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity).  Required for normal cell proliferation (By similarity).
What are the official names of this protein?
Protein yippee-like 5.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Deteted in nucleus and at the centrosome during interphase. During mitosis, detected on the mitotic spindle, at spindle poles and at the midbody.
Protein: RL3_METLZ
Sequence: MRTVRPRAGSLAYYPRKRAKGIVPKYQSWPEYNGQPMLQGFAGYKAGMTHVIMIDDHKKSPTEGKEVMVPVTVIEIPAMTVAAIRVYVKDTYGKHPLTEVWAENLEALSGRITKAKTNNAAKATEKINAAIGDVVEVMVLMYTKPTELTGVPKKVPDLMEIRVAGGSAQERFDYALSILGTDVDMKSLLSEGQFADITGITKGKGFQGAVKRFGITLRKRKHARTKKERHIGTLGPWTPHHVRWQVPMPGQMGFQQRTEFNKRIIKIGENADEINPAGGFLHYGLVRNNYVLIKGSIPGPAKRLVRIRSATRMGEQKIQAPVVEYVSLQSKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ACP_CHLAB
Sequence: MSLEDDVKSIIVEQLGVDPSEVTENSSFIEDLNADSLDLTELIMTLEEKFNFEISEQDAEKLRTVGDVLAYIKTRQGQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC16_MOUSE
Sequence: MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Anaphase-promoting complex subunit 16, APC16, Cyclosome subunit 16.
What is the protein family that this protein belongs to?
Belongs to the APC16 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore.
Protein: CBG_PINCO
Sequence: MEVSVLMWVLLFYSLLGFQVTTARLDRNNFPSDFMFGTASSAYQYEGAVREDGKGPSTWDALTHMPGRIKDSSNGDVAVDQYHRYMEDIELMASLGLDAYRFSISWSRILPEGRGEINMAGIEYYNNLIDALLQNGIQPFVTLFHFDLPKALEDSYGGWLSPQIINDFEAYAEICFRAFGDRVKYWATVNEPNLFVPLGYTVGIFPPTRCAAPHANPLCMTGNCSSAEPYLAAHHVLLAHASAVEKYREKYQKIQGGSIGLVISAPWYEPLENSPEERSAVDRILSFNLRWFLDPIVFGDYPQEMRERLGSRLPSISSELSAKLRGSFDYMGINHYTTLYATSTPPLSPDHTQYLYPDSRVYLTGERHGVSIGERTGMDGLFVVPHGIQKIVEYVKEFYDNPTIIIAENGYPESEESSSTLQENLNDVRRIRFHGDCLSYLSAAIKNGSDVRGYFVWSLLDNFEWAFGYTIRFGLYHVDFISDQKRYPKLSAQWFRQFLQHDDQGSIRSSSSI
What is the function of this protein?
Involved in the release of monolignols for lignin biosynthesis.  Unable to hydrolyze 4-nitrophenyl beta-cellobioside or alpha-linked methylumbelliferyl glucoside.
What are the official names of this protein?
Coniferin beta-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: VOSA_PENRW
Sequence: MLNNTSSDFDLIIRQQPNRARVAGGKEKEERPVPVAPSTALAGTLVSSLHRLKDVDNSDGGFFVFGDLSVKIEGEFRLKFTLFEMRKDRVSYLKTVISERFTVSPPKSFPGMMESTHLSRSFADQGVKLRIRKEPRTMLKRSTRPDEFHQPVPTRSPERQSVQIPPSSSYGGYPPAARDYGYYGQQPPVKRHRTSIDYGRQQGLYDVDGRMARQMDPYGQPTAAMYAGQPAAYQTPAAMQTYNTGQVVPDYTAMYPGMQASAGMQASAPMSQIPDPTGQSRSSQQQQAAVGQLMAMNQPGTPTPDSTGAMMAQGYARSGYPPSSTILPPLQRSRDYPQGTNGSARAYFDQTPQANTPILPSQMVNEGDRFSSVTGPTTFNHPDSPNGTPQ
What is the function of this protein?
Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (PubMed:23264641).  The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).
What are the official names of this protein?
Spore development regulator vosA.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VosA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIKD_STAA3
Sequence: MSLIDIQNLTIKNTSEKSLIKGIDLKIFSQQINALIGESGAGKSLIAKALLEYLPFDLSCTYDSYQFDGENVSRLSQYYGHTIGYISQNYAESFNDHTKLGKQLTAIYRKHYKGSKEEALSKVDKALSWVNLQSKDILNKYSFQLSGGQLERVYIASVLMLEPKLIIADEPVASLDALNGNQVMDLLQHIVLEHGQTLFIITHNLSHVLKYCQYIYVLKEGQIIERGNINHFKYEHLHPYTERLIKYRTQLKRDYYD
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import system ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEF_XANC8
Sequence: MNTPEDSSLGREVAYPSGYDPSLLFPIPRAAGRAAIGLRGALPFVGRDRWHAYELSWLDAHGKPCVATATLHVPCESPALIESKSLKLYLNSLNATRFNSAEAVRARIATDLSTRAGADVSVEFGLPPIDAVGEGESIDALDIAIDDYGPPKADYLATHAGTVVEEVLASALLKSNCPVTGQPDWASVTLRYRGAPIDREGLLRYLVSFRDHADFHEQCVERIFQDLLVRCAPQWLVVEARYTRRGGLDINPVRTSPQMPTPLSIFRDLRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2672_CLOBL
Sequence: MDMKKLIERINFLYKKSKEEGLTEEEKVEQQKLRREYIDIIKGNVKVQLEGVEKIPTANRKN
What are the official names of this protein?
UPF0291 protein CLI_2672.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAF1_CAEEL
Sequence: MPQESSDAKRIEPPRKVDFMLKPRFTNTVPDVPFDAKFMTCPFVPLGRFVEFQPAAIYRDYKHAVICDDDMGLNVDLIDLKKYDEDPIETEIDEKDNILLEDDGAAKLIAKRSQQHSKLVPWMRKTEYISTEFNRFGVTADRQETKLGYNLKKNQQVEDMYRDKQSQIDAINKTFEDVRKPVKEHYSKKGVKAVEESFVFPDFDHWKHLFAHVQFDGDTITTEFEEEDERQQARESSVIKAMEFEDQKFAAVFVPTIGCLTSFMDDLELERPFDEDMKYEFLLSREYTFKMEHLPPRDRDVFIMYHRNNVFQYNEVDCNVKMTRKPKMALSRKSKLTLTYRNPSELEQKDMNKREAELYEQPKTRKQEILEKIQEKKEEGGDSSDQSSDSDDDKPQKSRSDSSSDVSSDDDSPRKKEPTVDSDSD
What is the function of this protein?
Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
What are the official names of this protein?
RNA polymerase II-associated factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PAF1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear localization depends on PAF1 complex components ctr-9, leo-1 and cdc-73.
Protein: DNLJ_ERWT9
Sequence: MESLQDKITHLRTLLRHYEYQYHVLDAPAVPDAEYDRLMGELRELEAAHPELLTTDSPTQRVGAAPLSAFEQVRHEVPMLSLDNAFDEESYRAFNKRVQDRLKSSDDLTFCCELKLDGLAVSLLYEQGELVRAATRGDGTTGENITANVRTIRAIPLRLSGDNIPERLEVRGEVFMPLAGFEKMNEQARRGGQKIFANPRNAAAGSLRQLDPRITAKRPLTFFCYGLGLLEGGEMPRSHMARLQQFKAWGLPVSDRVRLCHSPSDVLDFYHQVEADRPALGFDIDGVVIKVDSLEQQEQLGFVARAPRWAVAFKFPAQEQITTVRDVEFQVGRTGAITPVARLEPVLVAGVMVSNATLHNADEIERLGLRIGDRVVIRRAGDVIPQVMSVVESAEGARDVIFPTHCPVCGSDVERVEGEVVARCTGGLICGAQRKGALKHFVSRRALDIDGMGEKIIDQLVDKEYVKNPAELFELTAGKLTGLDRMGPKSAQNVVDALAKAKQTTFARFLYALGISEVGEATAANLAAHFGTLEALMAADIDTLITVPDVGKVVASHVRNFLDEESNREIIRLLVEKAGVNWPDVVVVKAEEIDSPFAGKTVVLTGSLSILSRDDAKERLQALGAKVSGSVSKKTDLVIAGEAAGSKLAKAQELGIDVIDEQEMMRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.