PharMolix/UniProtQA huggingface dataset:
Protein: PEPB_VIBCH
Sequence: MSTQMSVFLSTQAAQPQWGEKALISFAEQGATIHLQQTQDFSAIQRAARKLDNQGIRTAFLAGEGWDLESIWAFYQGYRDAKKRNTVEWKALAAAEQVELEARIKATDWTRDIINKSAEEVAPRQLATMAAEFIKSLAPDHVSYRIVKDKDLLTEGWEGIYAVGRGSERTSAMLQLDYNPTGDENAPVFACLVGKGITFDSGGYSLKPSNMMSAMKADMGGSGMITGALGLAIMRGFNKRVKLILCCAENMVSGRALKLGDIITYKNGKTVEIMNTDAEGRLVLADGLIYASEQKPQLIIDCATLTGAAKNALGNDYHALLSYDESLSQQALAAAKEENEALWALPLAEFHREMLPSNFADLSNISNGDYTPGASTAAAFLSYFVEGYQKGWLHFDCSATYRKSASDKWAAGATGMGVKMLARILMQQA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCYD1_ARATH
Sequence: MEAGERRNGDSMSHNHRAPKKPRLAGLLTESDIDSEFAHHQTGVARINNGSFGCCPGSVLEAQREWQLRYLRQPDEFYFNGLRRGLLASRTVISDLINADDVDEVSLVDNATTAAAIVLQKVGRCFSEGKYKKEDTVVMFHCAFQSVKKSIQAYVSRVGGSTVEVRLPFPVNSNEEIISKFREGLEKGRANGRTVRLAIIDHITSMPCVLMPVRELVKICREEGVEQVFVDAAHAIGSVKVDVKEIGADYYVSNLHKWFFCPPSIAFFYCKKRGSESDVHHPVVSHEFGNGLPIESAWIGTRDYSSQLVVPSVMEFVNRFEGGMEGIMMKNHDEAVRMGLMLADAWGTNLGSPPEMCVGMVMIGLPSKLCVGSDEDAIKLRSYLRVHYSVEVPVFYLGLRDGEEGVKDKDSGLITAYVRISHQVYNKTEDYERLRDAITELVKDQMTCQNLPAL
What is the function of this protein?
Catalyzes the production of hydrogen sulfide (H2S) from cysteine.  Is mainly responsible for the degradation of cysteine to generate H2S, a regulator of stomatal movement and closure.
What are the official names of this protein?
L-cysteine desulfhydrase, AtL-CDes1, L-CDes1, AtLCD.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL7_ACIBT
Sequence: MALTNEEILNAVAEKTVLELVELISAFEEKFNVSAAAVAVAAPAGGAAAAAEEQSEFNVELTSFGANKVAVIKAVREATGLGLKEAKDLVEGAPQVLKEGVSKEEGEELKKKLEEAGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MURC_TRIV2
Sequence: MNNSVDFGGRPFHFIGIGGIGMSALAYVLAKRQLPVSGSDLRPNHITRKLESIGAHIFSRQEASNLEFFGSKVSSTEIELNTQEMFPLGKSTLPQVVCSTAINSNNLEYQAAIELGCPILHRSDVLAALINDYHSVAVAGTHGKTTTSSMIGYMLLEAGLDPTIIVGGEVNAWEGNARLGQSPYLVAEADESDGSLVKHAPEIGIITNIELDHPDHYDTLEEVVDIFQTFAKGCKTLIGSVDCATVRELLRTAASDRQQPTITYSLHQDTEADYTVTNIDCRADGTTALVWEKGKALGVLKLKLLSRHNLSNALAAVAVGRLVGLEFGEIAKGIAGFEGARRRFEFRGEVDGITFIDDYAHHPSEIRATLAAARLQARPGQRVVAIFQPHRYSRTLTFLEEFSESFSHADLVVLTDIYSAGEPNLGLISGEQLAEKIAQEHPQVVYQPTLSTVCEYLLKNLRPGDLALFLGAGNLNQAIPEIITTLCEPATATL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC2_STRP3
Sequence: MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYTKGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACSA_AGRRK
Sequence: MSEKIHPVTKPVKARALIDQAKYQKWYRQSVEDPDKFWGKHGQRIDWFKPYTKVKNTSFTGKVSIKWFEDGLTNVSYNCIDRHLKKHGDRVAFIWEGDNPYIDKKVTYNELYEHVCRLANVLKKHGVKKGDRVTIYMPMIPEAAYAMLACARIGAVHSVVFGGFSPEALGGRIVDCQSTFVITCDEGLRGGKPIPLKENTDTAIHIAAKQFVTVEKVLVVRRTGGKTGWAPGRDLWYHEETAKVKADCPPVKMKAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAAMTHEYTFDYHPGDIYWCTADVGWVTGHSYIVYGPLANAATSLMFEGVPNYPDQGRFWDIIDKHKVNIFYTAPTAIRSLMGAGDHFVKRSSRSSLRLLGTVGEPINPEAWEWYYKVVGDSRSPIVDTWWQTETGGHMITPLPGATDLKPGSATLPFFGVQPELVDSEGKVLEGAADGNLVIADSWPGQMRTVYGDHERFIQTYFSTYKGKYFTGDGCRRDEDGYYWITGRVDDVLNVSGHRLGTAEVESALVSHKHVSEAAVVGYPHSIKGQGIYCYVTLMVGQEGSDALRQELVKHVRAEIGPIASPDKIQFTPGLPKTRSGKIMRRILRKIAEDDFGALGDTSTLADPAVVDDLIANRQNKADAA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DPOL_HHV11
Sequence: MFSGGGGPLSPGGKSAARAASGFFAPAGPRGASRGPPPCLRQNFYNPYLAPVGTQQKPTGPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGGDERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHAYGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNKEEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFEAEVVERTDVYYYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPGFVTFGWYRLKPGRNNTLAQPAAPMAFGTSSDVEFNCTADNLAIEGGMSDLPAYKLMCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHVLLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSKIKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYYAAGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIYDGQQIRVFTCLLRLADQKGFILPDTQGRFRGAGGEAPKRPAAAREDEERPEEEGEDEDEREEGGGEREPEGARETAGRHVGYQGARVLDPTSGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEIEVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDKQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHARWAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAVGDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGVDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPEGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLAALRELDAAAPGDEPAPPAALPSPAKRPRETPSPADPPGGASKPRKLLVSELAEDPAYAIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWHPPDDVAARLRTAGFGAVGAGATAEETRRMLHRAFDTLA
What is the function of this protein?
Replicates viral genomic DNA.  The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein.  Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction.  Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus. Note=The protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Protein: Y3351_ARATH
Sequence: MLIVCRNSKSQDLDLYVKGVHFHLNKTLAKRSAKVTTLLESNKLHELRWIIRDMDINPSIFHLVTRFCYGYKIELSADNIVSVLCIAYYLEMSDDHSSNNLLNKAVTFLEQRVLMSWSETVKALCICSDKILDKLANVGLIEVFLDSLIEKALNDTRLLQDLITLPLRLYEPLILEVSKHNVSLENLVASVCNYANRWVFEKDSGDGSVSRNKREGIEAVERLLPHQRGTISSGFLFKSLKESIFLGACSDCRKGFEVRISNQLDMARAKDLQILSPTEDGSYDIELLKTILKSFYSNDSVPDLSRFVSVARMLEEFLLEAAASDAGLRVGTFKELAEIAVAASCDVLSYSDGIYRAIDVYLERHRDLIESEKMEACRFLHCKKLSPEACEHASKNEKLPLRIVMQVLFVSQMQIRDKVAREMKGVVERTENQVDEVESMSKKLLKLEIEPDYMKKRKIENLECVVHCEKKKTSVWREVKRKFGCMTSSTMDACSCHIKKRKTYHSYK
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At3g03510.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: CASP3_POPTR
Sequence: MSARVDIPADTSAAAKGTAPLIAASTHVKGGYKKGLAIFDLVLRLGAVVTALAAAATMGTTDQTLPFFTQFFQFQASYDDLPTFQFFVIAMAIVSGYLVLSLPFSIVAIIRPHATGPRLLLIILDTVALTLNTAAAAAAVAIVDLAQNGNSSANWLGICQQFGDFCQKASGAVVASFIAAGVLLFLIVISALALRKR
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 3, PtCASP3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: AROC_ECOLU
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL32_MARSD
Sequence: MAQPKKKTSKSRRNMRRSHDHVATPNVVYCECGEPIIPHRACSSCGSYKGRQVINSEDA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: HTPX_VIBC3
Sequence: MKRILLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLLMSKSMALRSVGGVVIDTPRNEMEHWLLETVRRQANQAGIGMPTVAIYDAPDMNAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANIVASRDSEEGEGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADAGAAQLVGKHKMIAALERLKMGQESHLEGSMMAFGITGKRSLSELMMTHPPLEKRIAALRNM
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL5_ENTFA
Sequence: MNRLKEKYIKEVTPSLVEKFNYSSVMQTPKVDKIVINMGVGDAVSNAKNLDKAVEELALITGQKPLITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTANTDEESRELLAQLGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MEND_HALHL
Sequence: MRTEDLNATWAGSLLDRLRGHGVHDVCIAPGSRSAPLALAAARRADRGDDLTLHTHFDERGLAFYALGLIRASRRPVAVITTSGTAAPNLHPAVAEARQSSLPLVVITADRPPELHHCGANQAMPQEDLFAPLVRAALALPPPEATLCGHWLNRRLDATLAEATGAGATGPIHLNVPLREPLYGGTEHPPVAPPLPPRRAPRAAAPPLGPAEPPQLFVAGGLNPEEAEAVLETAAAGNIPILADPSSQLRLRAHPCILGGAEHLLATAAGRAALGQARQVVQFGGRLTGRRLPAWLTEHAPQRWLITGDDHDLDPDWQATTVQADIATAARALRPAAPQPPLPGLTEALTRVAETRSAALANEPFAEPAATERLSRTLPPGMALFAGNSLPIRAVDLFAVAKHGNPCVTQRGVSGIDGLIATAAGFAHHHPDGVTLVIGDLSALHDLNSLALLDQARHTCVVVVLNNDGGGIFDLLPARSEGDDAHRRLFRMPHGYGFSQAAAQFRLPYWQCTDGDSLEAAHREACTRPGGSVIEVACPPGAGSEQMANLFRTLEAL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: AB4C_MAIZE
Sequence: MPPSFPSLPLPEAVAATAHAALLALAALLLLLRAARALASRCASCLKAPRRRGGPAVVVGDGAGGALAAATAGAWHRAVLASCAYALLSQVAVLSYEVAVAGSRVSARALLLPAVQAVSWAALLALALQARAVGWARFPALVRLWWVVSFALCVVIAYDDSRRLIGQGARAVDYAHMVANFASVPALGFLCLVGVMGSTGLELEFTEDGNGLHEPLLLGRQRREAEEELGCLRVTPYADAGILSLATLSWLSPLLSVGAQRPLELADIPLLAHKDRAKSCYKAMSAHYERQRLEYPGREPSLTWAILKSFWREAAVNGTFAAVNTIVSYVGPYLISYFVDYLSGNIAFPHEGYILASIFFVAKLLETLTARQWYLGVDIMGIHVKSGLTAMVYRKGLRLSNASRQSHTSGEIVNYMAVDVQRVGDYAWYFHDIWMLPLQIILALAILYKNVGIAMVSTLVATVLSIAASVPVAKLQEHYQDKLMASKDERMRKTSECLKNMRILKLQAWEDRYRLQLEEMRNVECRWLRWALYSQAAVTFVFWSSPIFVAVITFGTCILLGGQLTAGGVLSALATFRILQEPLRNFPDLISMMAQTRVSLDRLSHFLQQEELPDDATINVPQSSTDKAVDIKDGAFSWNPYTLTPTLSDIHLSVVRGMRVAVCGVIGSGKSSLLSSILGEIPKLCGHVRISGTAAYVPQTAWIQSGNIEENILFGSQMDRQRYKRVIAACCLKKDLELLQYGDQTVIGDRGINLSGGQKQRVQLARALYQDADIYLLDDPFSAVDAHTGSELFKEYILTALATKTVIYVTHQVEFLPAADLILVLKDGHITQAGKYDDLLQAGTDFNALVSAHKEAIETMDIFEDSDSDTVSSIPNKRLTPSISNIDNLKNKMCENGQPSNTRGIKEKKKKEERKKKRTVQEEERERGKVSSKVYLSYMGEAYKGTLIPLIILAQTMFQVLQIASNWWMAWANPQTEGDAPKTDSVVLLVVYMSLAFGSSLFVFMRSLLVATFGLAAAQKLFIKMLRCVFRAPMSFFDTTPSGRILNRVSVDQSVVDLDIAFRLGGFASTTIQLLGIVAVMSKVTWQVLILIVPMAVACMWMQRYYIASSRELTRILSVQKSPVIHLFSESIAGAATIRGFGQEKRFMKRNLYLLDCFARPLFSSLAAIEWLCLRMELLSTFVFAFCMAILVSFPPGTIEPSMAGLAVTYGLNLNARMSRWILSFCKLENRIISVERIYQYCRLPSEAPLIIENCRPPSSWPQNGNIELIDLKVRYKDDLPLVLHGVSCMFPGGKKIGIVGRTGSGKSTLIQALFRLIEPTGGKIIIDNIDISAIGLHDLRSRLSIIPQDPTLFEGTIRMNLDPLEECTDQEIWEALEKCQLGEVIRSKEEKLDSPVLENGDNWSVGQRQLIALGRALLKQAKILVLDEATASVDTATDNLIQKIIRSEFKDCTVCTIAHRIPTVIDSDLVLVLSDGKIAEFDTPQRLLEDKSSMFIQLVSEYSTRSSCI
What is the function of this protein?
ABC transporter that may affect phytic acid transport and compartmentalization.  May function directly or indirectly in removing phytic acid from the cytosol or in vesicle trafficking.  Required for phytic acid accumulation in developing seeds.  Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
What are the official names of this protein?
ABC transporter C family MRP4, Multidrug resistance-associated protein 4, ZmMRP4, Protein LOW PHYTIC ACID 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FBD3_ARATH
Sequence: MARTEVSGKDRLSDLPCHLLCRILSNLSTKESVRTSVLSPRWSNLWSLVSVLDLDFQDFKGEHDMGEFIDSFMEYHEELGLKLKSFNMFYDANEHLHEPFVRRLNKVVRRGVCDLNIQNMVDVDVALVRMPPSLYSCATLVNLILYCVVFDHPRSKSVSLPSVKKMYFEGVKFDGDSVLETLISHSPVLEELTVIPHPEDYLEVICVRSQSLESFRLESKRFECDNPKVEIDSPSLEFMSICDKKPESLKIHRIGPFAEVTVDVEFDVEDDDPLEISKIRKFLVGLSTFHELTISARTLESIHDYSKVGPLPPFSNLFGLDASLVESSWEVLPAFLSCCMNLDSLVIELDCVPEMEEIKLSPVPQCVLSSLDFLQLKAPSTPSKMKLATYFRKKCTRLTKMLLSGQ
What are the official names of this protein?
FBD-associated F-box protein At1g60410.
Protein: LMF2_HUMAN
Sequence: MAGSRLPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWETPTLLWEAPRLGLDTAQGLELLSLLGALVALGALLLSPLRHPVIYLLLWAAYLSACQVGQVFLYFQWDSLLLETGFLAVLVAPLRPASHRKEAPQGRQAGALPHEDLPFWLVRWLLFRLMFASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVPPLFFAPIRRLRLAAFYSQVLLQVLIIITGNYNFFNLMTLVLTTALLDDQHLAAEPGHGSRKKTATSWPKALLATLSLLLELAVYGLLAYGTVHYFGLEVDWQQRTIHSRTTFTFHQFSQWLKTLTLPTVWLGVASLVWELLSALWRWTQVRGWLRKLSAVVQLSLVGTATVALFLISLVPYSYVEPGTHGRLWTGAHRLFGAVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHHWTEIEFMYKPGNLSRPPPVVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLVQSQVARYPFHKQPPTYVRAQRYKYWFSQPGEQGQWWRRQWVEEFFPSVSLGDPTLETLLRQFGLQEKSPPRTRSANSTLAQALHWTRSQLSPLEAPALLWGLLMAVGAVRFVQALLAPCSLRSSPLAPVSGEKRRPASQKDSGAASEQATAAPNPCSSSSRTTRRKK
What is the function of this protein?
Involved in the maturation of specific proteins in the endoplasmic reticulum.  May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity).
What are the official names of this protein?
Lipase maturation factor 2, Transmembrane protein 112B, Transmembrane protein 153.
What is the protein family that this protein belongs to?
Belongs to the lipase maturation factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EST1A_MOUSE
Sequence: MAEGLERVRISASELRGILATLAPQAGSRENMKELKEPRQRKDNRRPDLEIYKPGLSRLRNRPKTKEASGNEEFKDEIVNDRDSSAVGNDTQLIQVCKELDSQQQNGPIDAENSQAQETFPKTVGLEDRSLKIIKRSKKPDLQIYQPGRRLQTITKESAGRADEEEILNQVEQLRIEEDECKGEAIKEEVNNKPDKTEIEKHQSNDRVRTAKGEKGKKIEKGEGSKKVADDSVPGKPGSVKRYSRSDKRRNRYRTCSTSSAGSNNSAEGAGLTDNGCRRRRQDRAKERPRLKKQVSLSSTDSLDEDRVDEPDVLGSRRSSERKKHLERNWSGCGEGEQKSNGKENRSALRVTFDAETMSKDSPVVRSVKDNVDRMKSDKGPSSGGKGSEKQELRHPRQELRDRGRGILILPAHTALSVSSSGSPESTPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKSQTPQLHFLDTDDEISPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYAGYSPLQYPVGPTNGMYPGAYYPGYPAPSGQYVCSPLPASTMSPEEIEQHVRNMQQQELHRLLRVADNQELQLSNLLSRDRISTEGMEKMAQLRTELLQLYERCILLDIEFSDSQNVDQILWKNAFYQVIEKFRQLLKDPNSENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYALISAQRSMICQGDISRYREQANDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDMSPDKWRKGKKSTFRHVGDDTTRLEIWIHPSHSRSAQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAASLGLAMFSLLVQRCTCLLKDSAKAQLSSPEDQEDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPLQVAVDVWSTLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGKQLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDQSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLERRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDYMPTSKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
What is the function of this protein?
Plays a role in nonsense-mediated mRNA decay.  Is thought to provide a link to the mRNA degradation machinery as it has endonuclease activity required to initiate NMD, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.  Degrades single-stranded RNA (ssRNA), but not ssDNA or dsRNA.
What are the official names of this protein?
Telomerase-binding protein EST1A, Ever shorter telomeres 1A, Nonsense mediated mRNA decay factor SMG6, Smg-6 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, telomere. Cytoplasm, cytosol. Note=Particularly enriched in the nucleolus.
Protein: REP75_PYRAB
Sequence: MVIYTSKFKNSLLDGLGVGHLSYDDQPILCNEVHPTLTLDTFISGGSSGSRPRPRWVYLDISTTNEGISEEFSSNTESKSPLLKVCGVSSKSSEGDGSSFIWFDKYRSVISRLEHSGFVEVERTVLKLRKISKELRSINKQLSRLFLDDRERAKLLSRKRKYLDFARALIGSISKSLTLYADRFFVEVPQDYAKLIQKLGFSSDTLLLHLFVNSGVLEVFLDDNSSHKFRIAYISKVHAGKYHPVKGISKGSQEAKRVLRDLLVLSELLEGSLVSYRSGGVETIHHLIPVRHFVLTAPKELSFSIWASLKKGDSSLFRAFKDAGAKAIKEFLSYLASKEHISGNLLFGFTINVHVTGDKNPFEPHFHIDAIVTFICYDKSSTKWFRLNPLLSESDLKKLRDIWKNVLLSYFGELLSEDTKSKDFDVWAGDNYYSLPLDVPQVFFELKYASRKLFVNFVNYFEQSNFDESSVSDWDFVRFVFEYSNRTERYGFLTNIKRYLSMSCSHLVEKRVQELEEFISRIEFDLSVNGNKMSDSLKRALLERLEYLKDELSELKERGFEYLFERALEKAEELLSNDNLTLERVIHILETLFTALGKSIVNYNFYVELEDVSFREFVDYLYDNHLSDVLVFSDRHRSITIIRLIPPPDGGVPV
What is the function of this protein?
Required for rolling circle plasmid replication, has a site-specific endonuclease/ligase activity (nicking and closing).  In vitro (no in vivo system yet exists) cleaves the double-stranded origin of replication (dso) site, on an ssDNA template, remaining covalently linked to the 5' end.  Religates the appropriate substrates.  Has nucleotidyltransferase activity, adding ATP or dATP to the 3' end of the nicked ssDNA site.  Both activities require a G nucleotide at the 3' end of the nicking site.  Also has topoisomerase activity, nicking and relaxing negatively supercoiled plasmids in a narrow concentration range (25-50 molar ratio of protein:DNA).  Topoisomerase is not dependent on a dso sequence.  Has no topoisomerase activity on slightly positively supercoiled plasmid.
What are the official names of this protein?
Replication initiator protein, Rep75 protein, ORF1.
What is the protein family that this protein belongs to?
Belongs to the Gram-positive plasmids replication protein type 1 family.
Protein: IF2_CORDI
Sequence: MPGKLRVHELAKQLGVTSKELLATLKDQGEFVKTASSTIEPPVVKKMKKHYESLGVTTEAPAASQEPKAKKPAAPKPAAPKPAATPQQAAKPAAPKPAAPKPAAEKKPAPKPAAKPVPKPGFSAAKAESSAPKPAAPKPAAPKPAAQSSTTATPGSMPRPQAKPAPKPGGRAPRVANNPFSSGPRPAPRPGGGNRSGNAPRPGGGPRPGGNRPQGGQGGPAERAPRPGGRGGQPRPQGGSRSQQSGGQERQGGGRRPSPAMMPTHPNPGQMPSRSNGSRNGRGGAGGQGGRPGFGGGRPGGGGSAGGRGGRRGGTAGAFGRPGGAPRKGRKSKRQKRNEYEAMQAPNVIGGVRLPDGGGATIRLARGASLSDFAEKINADAAALVQALFNLGEMVTATASVNEETLQLLGEEMNYKVEVVSPEDEDRELLESFDLQFGEDEGTEEDLAKRPPVVTVMGHVDHGKTRLLDTIRKTNVGSDEAGGITQGIGAYQVTVNIDDLSRKITFLDTPGHEAFTAMRARGAKSTDIAVLVVAADDGVMPQTVEAINHAKAADVPIVVAVNKIDKPGASPDKIRGQLTEYGLVPEEYGGDTMFVDISAKQNINIDGLLEAVLLTADASLDLRANPDMDAQGVAIEAHLDRGRGPVATVIVQRGTLRVGDSVVAGDAYGRVRRMVDEYGNDVEEAGPSRPVQMQGLNGVPGAGDNLLVVEDDRVARQIANQRNARKRNALAAKTRKRVSLEDLDSVLKETSTLNLILKGDNAGSVEALEDALLKIEVDDEVQLNIIDRGVGAVTQTNVSLAAASDAVIIAFNVRAEGKATEEANAEGVDIRYYTVIYRALEEVEQALKGMLKPIYEEREIGRAEIRAIFKASAVGLIAGCMVESGKVRRNASIRLLRDGTVVADNAKIESLRREKDDATEVAAGYECGMVLSYPDIQVGDIIEVFEQVEVPRT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_AZOSB
Sequence: MTTTLTAPTPAAAEAPRKKWTVAEVQALFDLPFLDLVFQAQQVHRAHFAANEVQRSTLLSIKTGGCSEDCGYCSQSARYDTGLERERLLPLDEVLEHARAAKAKGSSRFCMGAAWRGPKDKDMAPVLEMVREVKKLGLETCVTLGMLKEGQAEQLAEAGLDYYNHNIDTAPEFYGQIVTTHTLQDRLDTLDKVRDAGINVCCGGIVGMGETQTSRAGLIAQLANMTPPPDSVPINNLVAIPGTPLADGGTIDGFDFVRTIAAARITMPTSYVRLSAGRQQMSDEMQALCFMAGANSIFYGERLLTTDNPESDRDDVLFARLGLRSV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.