PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_ACTP2
Sequence: MIEADRIISASPKREEEVIDRAIRPKLLADYVGQPSVREQMEIFIKAAKLRDEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLTNLEPYDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRDRFGIVQRLEFYSVDDLTSIVKRSADCLNLNLSPDGAYEVARRSRGTPRIANRLLRRVRDYADVRNNGVITSDIAKQALAMLDVDSEGFDFMDIKLLQAIVERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIATSRTYAHLGIAKLD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IF6_HYPBU
Sequence: MIEYLNVHGNPNIGVYIYANNKIALVPPTLTEKDKKKIEETLGVEVIETKIADMIINGVMIAGNDNGLLLPRIVKPEELDYLREHIGDKVRLEILEVRQTALGNLIAANNRGALVSPLIDKAILDKIKSVLGVETIYQRHLANIPTVGSMIVVTNRGGVVHPGVSDDEIRILNSVFGVEFTTATVNFGLYFVKAGLVANDHGALVGDETTGPELMRIQQALRLRG
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: RUVC_CHLAD
Sequence: MRALGIDPGTATMGWGVVERDGGVLRLVDVGALTTPAGMPQPERLLQLYNGLRAIIERLQPDTAAVEELFFGKNVNTALTVGQARGVALLALAQAGIPVYEYKPTAVKQAVAGYGGADKRQMQEMVRLTLGLATVPRPDDAADALAIAICHAYTAPTLQRFGVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NUOC_BURP6
Sequence: MASKIETLKANLEAALGARAVSLVEAVGELTLVVKASDYLEVAKQLRDDRSLGFEQLIDLCGVDYQTYGDGAYDGPRFAAVLHLLSVANNWRLRVRVFASDDDLPIVPSVVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPQEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PNP_CHLTA
Sequence: MAFETFSVALDKDKTLIFETGKIARQASGAILVKMNETWVFSSACAASLSEAVDFLPFRVDYQEKFSSAGRTSGGFLKREGRPSEREILVSRLIDRSLRPSFPNRLMQDIQVLSYVWSYDGKTLPDPLAICGASAALAISEVPQNCIIAGVRVGLVGGKWVINPTRDELSASKLDLVMAGTASAVLMIEGHCDFLTEEQVLEAIAFGQTYIAKICDAIEAWQKATGKQKNFSAVLDMPEDVQNVVSDFIREKFEKALSFRDKEALEQASKELEESVIANLVQEENSDFSLLNVKAAFKTAKSNQMRALIQDLGIRVDGRTTTEIRPISIETPFLPRTHGSCLFTRGETQSMAVCTLGGENMAQRFEDLNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVLPETSRFPYIIRLESNITESNGSSSMASVCGGCLALMDAGVPIKAPVAGIAMGLILDRDQAIILSDISGIEDHLGDMDFKVAGTAKGITAFQMDIKIEGITHKIMEQALAQAKQGRSHILNLMTQVLASPKGTVSKYAPRIETMQINTSKIATVIGPGGKQIRQIIERSGAQVDINDDGVINIAASTQESINKAKELIEGLTGEVEVGKVYNGRVTSIATFGVFVEVLPGKEGLCHISELSKQKVDNISDFVKEGDKLAVKLLSINEKGQLKLSHKATLED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_BACC0
Sequence: MARSLKKGPFVDDHLMSKIAKLNETEQKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHDADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ACCA_PROM1
Sequence: MARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQKIQVARHPQRPSTLDYIQMFCDDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGRDTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFIDTPGAYAGLIAEEQGQGEAIAVNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAGKAPEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSPDELRNNRYSKFRKMGKYLESQSIESEISV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ECOL6
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDHDKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: ADAS_MOUSE
Sequence: MAEAAAGEAGASERDPDAGRARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAATPAAPESGTIPKKRQEVMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLVLPTLRDWIQNTLGVSLEHKTTSKTSINPSEAPPSIVNEDFLQELKEARISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLGLEYYVIGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEHTEAAAREEILANGGSLSHHHGVGKIRKQWLKESISDVGFGMLKSVKEYVDPSNIFGNRNLL
What is the function of this protein?
Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i. e.  alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.
What are the official names of this protein?
Alkyldihydroxyacetonephosphate synthase, peroxisomal, Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Peroxisome membrane. Peroxisome.
Protein: MNMA_BURMA
Sequence: MTKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAQTIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTRVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKTVGEHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAVKDIASNTLYVVQGHDHPWLRSRELVAGNVSWVAGEPPADGARCGAKTRYRQADAPCAFGRAAQAGDERFSLVFDEPQWAVTPGQSAVLYDGDVCLGGGIIESAATGRAGTAPAGRAPALVEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_ACIAD
Sequence: MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSLTGDEYSDVIKTAVDACKGSVPIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQEGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESCPNLIGFKDSSGQIDMMTEVVQTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQRLIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATLGPQ
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: RS3_CLOB8
Sequence: MGQKVNPHGLRVGVIKGWDAKWYANKKNFADNLIEDNKIRKFVKKELFSAGISKIEIERAAKRVKLNIYTAKPGVIIGKGGSGIEALKNKLTQFVENKNVLINIVEVKSAEADAQLMAENIAAQLEKRISFRRAMKQTMQRAMKHGIKGVKTACSGRLGGAEIARTEHYHEGTIPLQTLRADIDYGFAEADTTYGKIGVKVWVYNGEVLPTKKVEKEEANA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PYRE_PSEAE
Sequence: MQAYQRDFIRFAIERGVLRFGEFTLKSGRTSPYFFNAGLFDSGLALARLGRFYAEAVIDSGIDFDVLFGPAYKGIPLAATTAVALAEQHQRDLPWCFNRKEAKDHGEGGTLVGAPLSGRVLIIDDVITAGTAIREVMQIIDAQGARAAGVLIALNRQERGKGELSAIQEVERDFGMPVVSIVSLEQVLEYLAEDAELKKHLPAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LEUD_SULIA
Sequence: MIIEGPVIKFGDKIDTDIIIPARYLKYTDPQYLAQHAMEPLDPEFYKKASKGVIIVAGKVFGMGSSREQAAIALKAAGVKAVVAESFARIFYRNAINNGLPVITLPNSTKEIDESSYVKIDVETGEILVGNKVLKGKGITGMALEILQAGGIMEYLKKMQTVNRN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: VATA_CHLTR
Sequence: MVATSKQTTQGYVVEAYGNLLRVHVDGHVRQGEVAYVSVDDTWLKAEIIEVVGDEVKIQVFEETQGISRGALVTFSGHLLEAELGPGLLQGIFDGLQNRLEILADTSLFLRRGEYVNAICRETVWAYTQKASVGSVLSRGDVLGTVKEGRFDHKIMVPFSCFEEVTITWVISSGNYTVDTVVAKGRTSTGEELEFTMVQKWPIKQAFLEGEKVPSHEIMDVGLRVLDTQIPVLKGGTFCTPGPFGAGKTVLQHHLSKYAAVDIVVLCACGERAGEVVEILQEFPHLTDPHTGQSLMHRTCIICNTSSMPVAARESSIYLGITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVKMKDGSEGSLTICGAVSPAGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDSVAEILEKKVPGWGESVKQASRFLEEGAEIGKRIEVVGEEGISMEDMEIFLKSELYDFCYLQQNAFDAEDCYCPFDRQIELFSLMNHIFNSRFCFDCPDNARSFFLELQSKIKTLNGQKFLSEEYQKGLEVIYKLLESKMVQTV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: LGT_RHOP5
Sequence: MSFALAFPVFDPVAFAIGPIVIRWYALAYIGGIVIGWFYARALIKNRRLWGGAAPIPLIAWDDFILWVTLGIILGGRTGYVLFYNLDFFIAHPIEIIELWKGGMSFHGGFLGCVIAVLAFGWNRKLPVATLGDLTCAVGPIGLFLGRLANFINSELWGRPADPSLPWAMVFPTGGPLPRHPSQLYEAALEGVVLFVILALMIRAGALRRPGLILGSFIGLYGVARIIGELFREPDPQLGFLWGGLTMGMLLSVPMVIVGAIVAARAWRRAPLTASASAGHT
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEXM_MOUSE
Sequence: MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP
What are the official names of this protein?
Lymphocyte expansion molecule.
Protein: GRCA_ECOHS
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: SHO1_AJECN
Sequence: MARMDFNNIVGDPFALIAWLLSFATCVISDIQGAFPNFAWWAVGYMLCAIIGISLVLASQTSHVYGVAIVGYLAAGLTFTTLAVNSLIYDDQASKQAGAAGFILQSMVTIVWIFYFGSSSQTSSRPYLDSMGAGKEHPSYRNSKPLSTNYGARPETVVSGNQPPQMYTSAQLNGFETSSPVSGYPPTAANGAENGTQNRFVGPAIGSQSNLGGGSTLGADHPSTPNEVSQPTVYPYRAKAIYSYEANPDDANEISFSKHEILDVSDVSGRWWQAKKASGETGIAPSNYLILI
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAC_RIEPU
Sequence: MKNSELLKIIWALKNGEIIAYPAESVFSLGCDPDNDKTIQKLLTLKNRSWEKGFILVSDNYDKLTKYIDDKKLTKFQKRIISFHDTFFPRTWVVPAKKCVSKLITGQFKSIAIRISRFEYIKNICLNYGKPIISTSANISNDAPCRTKNEVAKKFNQCVRTMNGKTLGNFQHSIVQDLLNGYLYRKR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_RICTY
Sequence: MTNIITRFAPSPTGFLHIGSARTALFNYLFARHNNGKFFLRIEDTDKKRSTKEAIAAIFSGLKWLGINWDGEVIFQSKRNSLYKEAALKLLKEGKAYYCFTKQEEIARQRQQALKDKKHFIFNSEWRDKGPSTYPADIKPVIRLKVPREGSITIHDTLQGDIVIENSHIDDMILIRADGTATYMLAVIVDDHDMGITHIIRGDDHLTNAARQIAIYHAFGYEVPNMTHIPLIHGADGTKLSKRHGALGVEAYKDMGYLPESLCNYLLRLGWSHGDDEIISMNQAIEWFNLDSLGKSPSKLDFAKMNSINSHYLRMLDNDSLTSKTVAILKQNYKISEKEVSYIKQAMPSLIVRSATLIDLAQLAYIYLVDSPMIYNQDAKEVIKNCDKDLIKQIIANLNKLEQFDKECIQNKFKEIAIYNGLKLNDIMRPVRALITGMTASPSIFEIAETLGKENILKRLNIIYYNLNF
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_THEYD
Sequence: MTAYLLHDELIFPHPEYADPDGLLAIGGDLSPDRLILAYKSGIFPWYNHKPILWWSPSKRPLIFPRLFKMSRSLYQTLKKDIYRVSFDKDFVTVIKGCATAPRKDSTGTWITEEMIEAYTLLHKLGFAHSVEVWFNDKIVGGLYGISIGRAFFGESMFTLMKDASKVAISCLVEHLILNNFYFIDCQITNKHLIRLGAYEIPRSVFLILLKEAVQKETLTNKWDRDFEFTSKTAKFLKEKLIPR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_SHEB5
Sequence: MSEQKLALNEYLKTDSDYLRGTIKEGLDSAVTGSFSDGDQQLIKFHGFYQQDDRDLRNERKEQKLEPLYSFMLRARVPGGICSPQQWLGVDKIASTLTSSNSIRLTTRQTFQYHGIPKRNLKTIIQDLDREALDSIAACGDVNRNVMCNPNPVESKLHEQAYAVAKQLSDHLLPHTRAYAEIWLDEEKLLSTEDETVEPVYGKTYLPRKFKMAVAVPPDNDVDVYTNDLGFIAVAENGELVGFNLTAGGGMGSTHGEVETFPRLADDFGFIKTEDVMKFAEAVMTVQRDWGNRVNRKRSRLKYTIVDHGYEKFKAEVELRAGVKFEPKRDVVIGDRGDRYGWVEGVDGKWHLTLFIESGRIKDLPGQTLQTGLREIAKIHKGDFRMTSNQNMIIAGVAAEDKATIEGLARKHGLLGQVLTQTRGHSIACVALPTCPLAMAEAERYFPEFIDHIDALQAKHGISEQAIVVRMTGCPNGCARPFAAEIGLVGKAPGRYNLYLGASFEGTRLNKMHRENIQEAEILAELDTLFGRYAVERDAGETFGNFTVRVGVVKAVIDAAKDFHG
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: SYT_BRUC2
Sequence: MSNTVSLQFPDGSVREYDASMTGAALAESISKSLAKKAVAYAVDGTVRDLSDPLGASGKVEIITREDPRALELIRHDTAHVLAEAVQELFPGTQVTIGPVIENGFYYDFARNEPFTLDDLPVIEKKMREIIQRNKPFTKEVWSREKAKQVFSDKGESYKVELVDAIPAGQDLKIYYQGDWFDLCRGPHMASTGQIGNSFKLMKVAGAYWRGDANNPMLTRIYGTAFANDNDLQAYLHMLEEAEKRDHRRLGREMDLFHFQEEGPGVVFWHAKGWKMFQNLVSYMRRRLDSHGYQEVNAPQVLDKSLWETSGHWGWYRDNMFKVTVAGDDTDDDRVFALKPMNCPGHVQIFKHGLKSYRDLPIKLAEFGNVHRYEPSGALHGLMRVRGFTQDDAHIFCTEEQMAAECLRINDLILSVYKDFGFEEITIKLSTRPEKRVGSDELWDRAESVMMTVLEQIRQQSNNIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIGADSEKKQPVMIHRAICGSMERFLGILIENFAGHMPLWFAPVQVVVATITSDADEYAKEAAAKLKAAGLQVVTDLRNEKINYKVREHSLQKVPVILVCGKREAEEKTVNMRRLGSRDQESMTLDEAIARLCEEATPPDLLRLKNAG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH5FP_CHAOB
Sequence: MTSAGVAPTALRLLTALLLLLVAAPSHSLPLLTRGRWIVDEATGLRVKLACVNWVGHLEPGLPEGLNRLPVATVAHTISSLGFNCVRLTYSIHMLTRTSYTNATVAQTFARLNLTEAASGIEHNNPELLDLGHVAAYHHVVAALSEAGVMVILDNHVSKPKWCCAVDDGNGFFGDRYFNPNTWVEGLGLMATYFNNTPNVVAMSLRNELRGNRSTPISWSRHMQWGAATVHKANPKVLVILSGLQFDTDLSFLPVLPVTLPFKEKIVYEGHWYSFGVPWRTGLPNDVCKNETGRFKSNVGFVTSSANATAAPLFMSEFGIDQRYVNDNDNRYLNCILAYLAEEDLDWALWTMGGSYYYRSDKQPVKDFEETYGFFNHDWSRIRNPDFISRLKEIQQPIQDPYLAPGPYYQIIYHPASGLCVESGIGNTVHLGSCQSVRSRWNYDASVKGPIGLMGSSSCISTQGNGLPAIMTENCSAPNNTLWSTVSSAQLQLGTRVLGKDGKEKWMCLDGSKSPLISTNECICITDSHCYPKLNPEKQWFKVITTNKQLLHQLQL
What is the function of this protein?
May have glycosyl hydrolase activity.
What are the official names of this protein?
Glycosyl hydrolase 5 family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: LPXC_ECO7I
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL35_BURCJ
Sequence: MPKMKTKKSAAKRFVVRPGGTVKRGQAFKRHILTKKTTKNKRHLRGATAVHDSDLNSVRAMLPFA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PIR32_CANAL
Sequence: MIHYLIFPILLIFFQIIKSSGYYVPANGDDWTILKPPSCKNKLPGQYIDSLPFTFGIVVNPYILNEDGDYEKPIVSKIKPSLTTTTFVTSIITTSTATAPGSKPTKTKDIIVQIHDGQVQKMKHKHDYSSGGGDDDDDDEDCFDEKNIDMAAKRDYQDMNTQEQANEDSGQVLAESDSHQQVVDQNQQINEEEEETQEQQMQEENNNTNEIEDNKVQEFETIEEIYDDIDNNESRPNNSKKYHKKRPHNNYENKHGHKDYHEDHHHNHRYKDHENGHEEDDHKWNKPKPMPEQEEQEQEQEQKPKHEKSEGYESEFVSPVYSVACYTNSTLKMTLTDGILRDSDDRIGCIVSGHQFQFDGPTPQHGAIYAAGWSVTKQGQLALGDSTKFYQCASGDFYNLYDEPIAFQCHPVTLDVVELIEC
What is the function of this protein?
Probable structural component of the cell wall involved in cell wall integrity and virulence.
What are the official names of this protein?
Probable cell wall mannoprotein PIR32.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall.