PharMolix/UniProtQA huggingface dataset:
Protein: Y2329_JANMA
Sequence: MMKNQLAGLMKQAQAMQDNMKKMQDQLASIEVEGQSGAGLVKVVMSCKNDVKRVSIDPSLLADDKDMLEDLVAAAFNDAVRKAEATSQEKMSGVTAGMPLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein mma_2329.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL10_PSEFS
Sequence: MAINLEDKKAIVAEVNEAAKAALSAVVADARGVTVSAMTGLRKEAREAGVYVRVVRNTLLKRAVADTEYSVLNDVFTGPTLIAFSTDHPGAAARLFKEFAKGQDKFEIKAAAFEGKFLAANQIDVLATLPTRNEAISQLMSVIQGATSKLARTLAAVREQKEAAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ACTL2_HYDVU
Sequence: MLSYLCFGCFLVSASLEIACGTPIKETSKADAGGGAGIAILGVLAKVGVEAALQQIDNIWKGDVVRYWKCAVENRSDKTLYAYGTTSESGSMGTVFADIPSGSTGIFVWEKSRGAATGASGVVHYRYGDKILNLMASIPYDWNLYQSWANARVSNEKESFYNLYNGLNGAKPATRGGNWGDVDGAKFFLTEKSHAEFKVIFSG
What is the function of this protein?
Pore-forming protein that forms hydrophilic pores and causes cytolysis (PubMed:31513812).  Compared to equinatoxin-2 (AC P61914), it reveals lower cytolysis activity (5-12-fold difference, tested on erythrocytes), a larger pore size (probably 2-3 nm) and different affinity to membrane lipids (100-fold lower affinity to sphingomyelin) (PubMed:31513812) (By similarity).  Binds to sulfatides (SFT) (PubMed:31513812).  Shows cytolytic activity on HeLa cells, with a different potency than its paralogs (from most potent to less potent: HALT-4>HALT-6~HALT-1>HALT-3>HALT-7>HALT-2) (PubMed:31513812).  Pore formation is a multi-step process that involves specific recognition of membrane lipid by a protein aromatic residues rich region, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  In vitro, binds to the folate receptor alpha (FOLR1), a GPI-anchored membrane protein that plays a major role in the uptake of folate/folic acid into cells via endocytosis, suggesting a possible involvement of this receptor in the mechanism of HALT-1-induced cell lysis (By similarity).  In vivo, does not cause visible paralysis in larvae of the blowfly Sarcophaga faculata, the most common arthropod prey of Hydra (By similarity).
What are the official names of this protein?
Hydra actinoporin-like toxin 2, HALT-2, Alpha-pore-forming toxin, alpha-PFT, DELTA-hydritoxin-Hma1b, DELTA-HYTX-Hma1b.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. HALT subfamily.
Protein: PG110_MONPV
Sequence: MAWSITNKADTSSFTKMAEIRAHLRNSAENKDKNEDIFPEDVIIPSTKPKTKRTTTPRKPAATKRSTKKDKEKEEVEEVVIEEYHQTTEENSPPPSSSPGVGDIVESVAAVELDDSDGDDEPMVQVEAGKVNHSARSDLSDLKVATDNIVKDLKKIITRISAVSTVLEDVQAAGISRQFTSMTKAITTLSDLVTEGKSKVVRKKVKTCKK
What is the function of this protein?
Involved in the co-transcriptional or post-transcriptional endoribonucleolytic cleavage that generates sequence-homogeneous 3' ends during late transcription.  Involved in postreplicative transcription elongation on intermediate and late genes.  Also involved in DNA replication and in multiple steps of virion morphogenesis.  Required both for inclusion of virosoplasm into crescents as well as for maturation of immature virions (IV) into mature virions (MV).
What are the official names of this protein?
Late transcription elongation factor OPG110.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG110 family.
Protein: HEMH_COXB2
Sequence: MAKQAIKRAKILAVKNNNKIGVLLINLGTPDEPSVPAVRRYLRQFLSDPKVIDVPSLVRWIIVHLCILPFRPKRSAKLYQKIWMPEGSPLLVYSEMLRERVGETLGDDFCVALGMRYGKPSIETALKKLQEAQCRQLIVLPLFPQYSTSTTASALEGVRAKNSFKEMTVIDRFFEEPHYIDSMTTLIHENLNEFQPDYFLFSYHGLPERHLVKSGCQLAICNRKNNCSPISSSNENCYRAQCFETSRLIAKKLNLTDQQYGVAFQSRLGRAKWIEPYTDKYLIELSKKGIKKLMVVCPSFPVDCLETLEEIGIRAQSQWQRLGGETLKLIPSLNAHPQWVNAIAKMAKKSLQLF
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2AG_MOUSE
Sequence: MAYQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFRGSLNTYRFCDNVWTFVLNDVEFREVTELIKVDKVKIVACDGKNTGSNTTE
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with TBP mediates transcriptional activity (By similarity).
What are the official names of this protein?
Transcription initiation factor IIA subunit 2, General transcription factor IIA subunit 2, Transcription initiation factor IIA gamma chain, TFIIA-gamma.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMU_HELP2
Sequence: MLSVIILAAGKGTRMHSSLPKTLHTICGEPMLFYILETAFSISDDVHLILHHQQERIKEAVLKRFKGVIFHTQIVEKYSGTGGAIMQEDKTPIPTKHERVLILNADMPLITKDALTPLLESKNNAIGLLHLADPKGYGRVVLENHQVKKIVEEKDANDEEKEIKSVNAGVYGFERKFLERYLPKLHDQNAQKEYYLTDLIALGINENETIDAIFLEEEYFLGVNSQTERAKAEEIMLERLRKNAMDLGVVMQLPDSIYLEKGVSFKGECVLEQGVRLIGNCLIENACIKAYSVIEESQIVNSSVGPFAHARPKSVICNSHVGNFVETKNAKLQGAKAGHLSYLGDCEIGKNTNVGAGVITCNYDGKKKHQTIIGENVFIGSDSQLVAPINIGSNVLIGSGTTITKDIPSGSLSLSRAPQTNIENGYFKFFKKP
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFS11_MOUSE
Sequence: MSPESKKLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSLAIIYGVFSASNLITPSVVAIVGPQISMFVSGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISEHDRRTVFIALTVISLVGTVLFFLIRKPDPENVLGEEESCDDQDMEATESAQNNVTKAVDAFKKSLRLCVTREMLLLSVTTAYTGLELTFFSGVYGTCIGAVNKFGTEEKSLIGLSGIFIGIGEILGGSLFGLLSKNSRFGRNPVVLLGTLVHFVAFYLIFLNMPGDAPIAPVEGTNSIAYIRPSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEWDAAAIVARGSDYRSI
What are the official names of this protein?
UNC93-like protein MFSD11, Major facilitator superfamily domain-containing protein 11, Protein ET.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HISZ_LYSSC
Sequence: MFEKPLGMRDTFPQIFEKVEAVRQTGRDFLTKRGYEFIKTPAVEYFDTVGKASAIADTHLFKLVDSQGNTLVLRPDMTTPIARVATSKLLKEMIPQRLAYFASVFRAQEAEGGRPAEFDQMGIELIGDQSVFADAEVIVTAMELLKHLKLEAFKVTIGHAGILNCILQDYTESIEQQTTLRTLLVHRNYVGFEEAVDSFNLPKAKADALLQFIEEAMDVKDIRDIEKYVRKNDALVYMQQLAQLLEMADLAAYVTFDFTLSSHMSYYTGMLFEVFALGSGFPLGNGGRYDGLLEVFGSKAGATGFSIRVDRLLETLHGQSEMQQEATVVLFDEEQFEAALIKVNTLRAAGKLATLQLRSSLVDEEAFLAHFTEVVVVGQEEIGSE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_LACE2
Sequence: MRIIGLDVGTKTVGVALSDPLGITAQPFETITRKENNKLRRTYARIEQIISEYDVTEIVVGYPKNMDDTIGERAKACEEFAAALERRTGLPVTLWDERLTTVEADEVLEECGMRRENRKTVIDQLAAVFILRGYMESKQK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PHOPR
Sequence: MMVMDAKIFEIADKLYAQQALTQDESHVLFDAIIKGDVDPILLSAVLTALKIKGETPAEIAGAASALLANANAFPSPEYDFADIVGTGGDGANTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLDKFGINLAMTPENARGALDELGVCFLFAPEYHSGVRHAMPVRQTLKTRTIFNVLGPLINPARPKIELMGVYDQSLVRPIAETMVAMGMKRAAVVHGSGLDEVAIHGETLVAEIINGEIKEYTLTPADFGLETYPLEAIKGGEPEENRAIITDILTGKGTDAQQGAVAVNVALLLRLFGQEDLKANTQQAIAAMQSGKAYELVNKLAARG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TRPC6_BOVIN
Sequence: MNQSPAAFGPRRGGSPAVVAGAGARRNESQDYLLMDSELGDDAQPPLPAYGYYPCLRGTDSRLTHRRQTVLREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECLSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCSECNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVEIHHSGGDHYRPNLSRLKLAIKYDVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAVGLPFLALVYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKILPNETSTDHAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLRLKKWISELFQGHKKGFQEDAEMNKRNEGKKFGILGSHEDLSKLSLDRKQFAHSKQSSIRSSEDFQLNSFTNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEKTQNSEDLAELIRKLGEKLSMEPNQEESNR
What is the function of this protein?
Thought to form a receptor-activated non-selective calcium permeant cation channel.  Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.  Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C.  Seems not to be activated by intracellular calcium store depletion.
What are the official names of this protein?
Short transient receptor potential channel 6, TrpC6.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YGP9_YEAST
Sequence: MNNSIITDDEVREFYLNCSSQTIIESLLSLHESLRLYSQNHEILLNRMFKKLDETNADSNISHIFMPVVSKDFSGIKILVNNNNKNFQGVINVIEPETGKLIGCFEAKQITAIRTALASCIGLYKQLSCSHDKLFRFENGTCYLTCFGTGLQAFWHIYIAIKLIMSGIVGESLKLVEINILYHNNMMSLDRLKSLKNLFGSNIKIELNQYQINDISSEGNGAVSNSDIIFGCLPTLEPNLFLRQLLNSKASVEQKHTYISLIGSYKPVMHECDKELIDKFKSDNESACILVDSREHTLLESGELIDSNIAPHNLIEIGELDTLKNTVLNLNEKGCKRTITLCKIVGLAVMDVALAKEFLSLRTKNTENKE
What are the official names of this protein?
Uncharacterized protein YGL159W.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: GALD1_HUMAN
Sequence: MASERLPNRPACLLVASGAAEGVSAQSFLHCFTMASTAFNLQVATPGGKAMEFVDVTESNARWVQDFRLKAYASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCATNEDRSWVFDSYSLTGPSVCELVRAPGFARLPLVVEDFVKDSGACFSASEPDAVHVVLDRHLVTGQNASSTVPAVQNLLFLCGSRK
What are the official names of this protein?
Glutamine amidotransferase-like class 1 domain-containing protein 1, Parkinson disease 7 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: F16PA_ECOLC
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC6A_BOVIN
Sequence: MADPALFEFLHTEMVAELWAQDPDPGPGGQKTSLLVLEGMGFRVGQALGERLPRETLTFREELDILKFLCKDLWVAVFHKQMDSLRTNHQGTYVLQDNSFPLLVRMASGLQYLEEAPKFLAFTCGLLRGTLSTLGVKSLVTASVAALPACKFQVVIQKL
What is the function of this protein?
May play a role in vesicular transport during the biogenesis of melanosomes.
What are the official names of this protein?
Trafficking protein particle complex subunit 6A, TRAPP complex subunit 6A.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: COAX_NOVAD
Sequence: MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQILISTVVPRALHNLSVLAQKYFGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHAKYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLDALVNAAAKLPRIAIEAPTRTKSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDHVDTDLTLDGLAILAERVTVQ
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ANAD2
Sequence: MRLVVVAGPTASGKTALAIALARRLGGEIVNADSQQVYRGLDVGTAKPTAEERGAAPHHLLDLVEPGEGMDAARFAALADAAIAGIAARGRVPIVAGGTGLYVRALLHGVVEAPGRDPALRAALEEEAARLGRPAVHARLAAVDPAAAERIRPNDLVRVVRALEIAAGGRTPSELYQAHAFREDRYDAALLALDPPRAELHARIDARVRAMFAGGLLDEARALEARFVGALPARLPIGYAEAAAHLRGELDLEEAIRRVQVAHRRYARRQVIWLRRERGVAWIAPPHDVEALSRRVLEPRPPAIR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL11_PROM2
Sequence: MAKKIVAVIKLALQAGKANPAPPVGPALGQHGVNIMAFCKEYNARTQDKAGFVIPVEISVFEDRSFTFITKTPPASVLITKAAGIEKGSGESAKGSVGNISKAQLEEIAKTKLPDLNCSSVESAMKVIEGTARNMGVSITD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: AROD_STRPS
Sequence: MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: HRCA_BORPA
Sequence: MDDRARALLKALIERYIADGQPVGSRTLSKVFDLSPATIRNVMADLEELGLIHSPHTSAGRVPTPRGYRMFVDSLLAVRAYQFEPAHIGELLPVSEPSRAVNAAAALLSNLTQFAGVVLTPKRTQIFRQIEFIRLSDKRVLLIIVTPEGDVQNRILSAQRDYTEAELLEAGNFFNVHFSGKSFDAVRRTLSTELAQLRDDISRLMQAAVEAGAEAADDGEAVVISGERKLLDVTDIASDMDRLRKMFSLFEKKTDLLQLLDVSSRAQGVQIYIGGDSQLVPMEEVSVITAPYGVDGKVIGTLGVIGPTRMAYERVIPIVDITARLLSNALSHNQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL18_BURCJ
Sequence: MDKTQSRLRRARQTRIKIAELQVARLAVHRTNTHIYAQVFSPCGTKVLASASTLEAEVRAELADKSGKGGNVNAATLIGKRIAEKAKAAGIESVAFDRSGFRYHGRVKALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SELO_SALPK
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDELAQQLAIPASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYALWFEEVAARTGRLIAEWQTVGFAHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNVLLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDRYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHEVLRQPFTDRDDDYASRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: DHB13_HUMAN
Sequence: MNIILEILLLLITIIYSYLESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK
What is the function of this protein?
Does not have retinol/retinal dehydrogenase activity in vitro.
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, Hepatic retinol/retinal dehydrogenase, Short chain dehydrogenase/reductase family 16C member 3, Short-chain dehydrogenase/reductase 9.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation.
Protein: PAN_SULTO
Sequence: MSDELDSYRAKHYNSDDPIVRLLEEKIESLTKELEKLRQDLNWYKGELEKLLAPPYIEAIVLDILPDGKVIVRSSSGPNLIVNVSSNIDIKKLKPGSLVALTQRGSTIVEVLPEREDAYVKSFEVIEKPNVHYSDIGGLNEQINEIREVIELPLKNPELFKEIGIDPPKGVLLYGPPGTGKTLLAKAVATESNATFIQVVASEFAQKFVGEGARIVREVFELARRKAPSIVFIDEIDAIGAKRVDMGTSGEREIQRTLMQLLAEIDGFKPLDNVKIIAATNRLDILDPALLRPGRFDRLIEVPLPNFEGRKEIFRIYLQKMKTDGNIRYDILASMTEGFSGAEIKNVCTEAGYIAIRNGRKYVNMTDLITAIEKIKAKNNKAKNTDRTEKYV
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF233_ASFB7
Sequence: MILIASPFSLAHLEYLHTWHVTIKNIAQQHGLDIKVAIVVSTSHLNNFLPISGALNIECITFPSCGIKEIDLLWARIKLFQHYCAIGARLLWLVSADIRPPVSAWPAIADSLKKGADAVVIPYPSRWNNLIPTVIKEIVVHQKKCLVAVDARHLDTDTQIVGAGMGCIVLTLKALMVRLSIGKQPVKILWPDLHGTAEGIPLEGVEVGWFLNAYAHKLNIRCLGADHIAQHLT
What are the official names of this protein?
Uncharacterized protein H233R, pH233R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H233R family.
Protein: PHYT_BACSU
Sequence: MKVPKTMLLSTAAGLLLSLTATSVSAHYVNEEHHFKVTAHTETDPVASGDDAADDPAIWVHEKHPEKSKLITTNKKSGLVVYDLDGKQLHSYEFGKLNNVDLRYDFPLNGEKIDIAAASNRSEGKNTIEVYAIDGDKGKLKSITDPNHPISTNISEVYGFSLYHSQKTGAFYALVTGKQGEFEQYEIVDGGKGYVTGKKVREFKLNSQTEGLVADDEYGNLYIAEEDEAIWKFNAEPGGGSKGQVVDRATGDHLTADIEGLTIYYAPNGKGYLMASSQGNNSYAMYERQGKNRYVANFEITDGEKIDGTSDTDGIDVLGFGLGPKYPYGIFVAQDGENIDNGQAVNQNFKIVSWEQIAQHLGEMPDLHKQVNPRKLKDRSDG
What are the official names of this protein?
3-phytase, Myo-inositol-hexaphosphate 3-phosphohydrolase, Phytate 3-phosphatase.
What are the subcellular locations of this protein?
Secreted.
Protein: SCOA_HELPJ
Sequence: MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKTTTRSAK
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit A, Succinyl-CoA:3-oxoacid CoA-transferase, OXCT A.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: EFTS_HYDCU
Sequence: MAVTASMVKELREATGAGMMDCKKALAETDGNMEEAIEFLRKKGMAGADKKAGRTAAEGVIAIAVSDDKKKAAIVEVNCETDFVAKGDDFKAFADEIAAIVLATGTVDVDALMNEKMANGQTIDEKRREMIGKIGENMAVRRVELVESNGTIGKYQHGEKIGVVVAMNGGDDALVRDVAMHVAAANPSAISADDVDQEMLEKERKFQIEQAQDSGKPAEIIEKMIDGRMRKYLQEITLLGQAFVKDPDQTVEKLLKASDASVSNFVRLEVGEGIEIEETNFADEVAAAAAAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.