PharMolix/UniProtQA huggingface dataset:
Protein: NUCS_BIFLS
Sequence: MRVIVADCSAEYSGRLNASLPLAKRVLLIKADSSLLIFSELGSYKPLNWMTAPCTIREIDPAAKSAQHSRESVAGGAVDGDSATHSPESVAAGEPEKVLRVSADKGSDILEVTLQHIYSDQTYDLGEDPGLIKDGVEDHLQRYLAEQIERIGKGAKLVRREYPTAIGPVDIMAVNAEGEHVAVEIKRHGGIDGVEQLTRYCELLNRDPLLAPVHGIFAAQTITPQAQVLAKDRGFTCLILDYDDMKGTEDDSLRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_CHLTA
Sequence: MKVRLGVDMMGGDHDPLVVWEALGEVLLSSIGEQPVEFTVFATSDVHHQLMNSPLSRSVRIVTAEDFVSMEDSLLAAVRKKRSSMALGLDALQQGDLDGFVSSGNTAALVTLARSKIPMIPAVPRPALLVSVPTLSGFAVILDVGATVSVNPDEMVGFARMGLAYRQSLSSNSNQPFTLGLLNIGSEERKGTDSHKQTFRMLRNIFGSAFLGNIESGDVFSGKVDIVVTDGFTGNVFLKTAEGLFDFLRRILGDRLEKSIKMQFDYTIYPGSIISGLSRLVIKCHGKSHGTALFGGISGAIDLARANVCSRIADRFGDNVV
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: H2B8_ORYSJ
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKAPAGKKPKAEKRLPAGKGEKGSGEGKKAGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGESAKLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.8.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PYRG_BRASB
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATKADNITTGRIYQDILTKERRGDYLGATIQVVPHVTNAIKDFVLSGNDEYDFVLVEIGGTVGDIEGLPFFEAIRQLKNELPRDHAIYIHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDREIPKEERRKLGLFCNVRESAVIEARDVDNIYAVPEAYHAAGLDDEVLAAFGIEPRVPPALASWHTINERVRNPEGDVTIAIVGKYTGMKDAYKSLIEALSHGGIANKVRVKLDWIESEVFENEDPAPFLEHVNGILVPGGFGQRGAEGKIRAAQFARERDVPYFGICFGMQMAVIEAARNLVGITEANSTEFGPTKEPLVGLMTEWLRGNELERRSQSGDLGGTMRLGAYPAMLKRGSRVSEVYGGATEISERHRHRYEVNTAYKDRLEQHGLKFSGLSPDGVLPEIVEYADHPWFIGVQFHPELKSRPFEPHPLFASFIQAAVVQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NAPA_DICDI
Sequence: MAHTNLPEKFQVVIENGENILQRVYNTYKLFQNNKVKPSFFNDEKISKILKNLIAKYPELPENNDKSITGFDLLTSRAKQHLEELEDHYYTITDAYDWKEASFILMQEISSNTVSINFNNNIQLCSKFLDVLVLYGKINYLVSLIPDKKIITAVYAKLFLYTRSASEPTFSKMGRWINDIEQPFKKIQEEFRVLNDAVGHALSSFELTYAKRRVITQLRKDGALNLILKPEDIARPVQDSYRIELAYAGRIQQWILFGYLFAPGTLSTPQSIELLRFTLSECFYLSVFKDISISIHNEFNTLFKNYKSKTINLQKQKKIIKDAAQASTQEAPRKHAERRVYIRQELEAMWNLFRDKPCLLAPKINVLLAALSMAKEEIFWYFRHTDVIPPEKVKKFYNKQNEVREKRISSLLSLVDHLVQLVHTHKKMIQNYYLEYISGADILGLQKVITPQLLQNAGSIVTQAVNTIVNELKSLNANGQDYSFEGFRANWMRLGYLLQSNSCPLKESESKQITSRLNLIYTHSKNVDCLDQLLDEYGNMTQLWSYKEPLFHSFDAAIVDMTCDQPSHSMIYLKLLSQFPNHVANQFYPEEKELIGKECVELANSCLTKITNRIVSIMANTIASTFLSDEQQLADVNAAFPLLQKKKDWKPPKDFVPPIEPASESQFRNRANLEQLRSEEKNAFQLCTALNEFLDITIYDHIFVPREFLREKLGSALKQYMRQSIQPPAPTSSSSQIDINITRLSTYESQLRVFIGVLILVENHVDIDIGDLIRETILTEFYAKALGKSGRVDWFPEGEIEMNELTLHSITSYYVDLVSKKLNTPGVVFSPVKLGFISKAGTPFRAEEHADLTEMRALCDLVGPYGIKVIEREILRFILTTTTSMKEILSLNAANLEEFASNYYKPKAMELLKKFKTTDLDLIVTKSIAIGNALHLRSMIRESMKDVITDNFPYINNAVANAFDQYNRNTFMFPDFLGVDTLALDSGLNVGIADQYLKVILRKVSSEADKRIWELLPVMFSLTFYGNIWKETQYKATIDAHSNNVHVLSKTIIDLLIAFGAINSTTGNEAELFQSFKRFLEISSVNILRMFKGKQGEKFVPNEIQSVIIFLDKFTQQCPLLSKDSLEQYIPYSLIRNMYKDLYEHKNLQKQQSETSEQNF
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Involved in cell adhesion.
What are the official names of this protein?
Nck-associated protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HEM-1/HEM-2 family.
Protein: ADA22_XENLA
Sequence: MHINGGPLASWICCVIGSIHLAHASTRPENGGTSGMQRKKENSVLGMEDTVPLRLIFSNEEDNQTTQGLLSTRVRAGSPQHQDQLTHVAQASFQIDAFGSSFILDVELNHDLLSSDYRERHVTQDGKTVEVKGGEHCYYQGQIRGKAKSFVALSTCNGLHGMFCDGNHTYLIEPGEKYNPNEDYQFHSVYKSKVLEFPLDELPSEFWALNDTSVRLSQQTRSQRKKRQTRRYPRNVEDETKYVELMIVNDHLMYKKHRLSVGHTNSYAKSVVNMADLIYKEQLNTRIVLVAMETWATDNKFSISENPLLTLKEFMKYRRDFIKDKSDAVHLFSGSQLRVAAVVLRILVEWCSLLKGGGVNEFGKPDVMAVTLAQSLAHNLGIFSDKKKLLSGECKCEDTWSGCIMGDIGYYLPSKFSVCNIEEYHEFLNNGGGACLFNKPLKLLDPPECGNGFVETGEECDCGTIAECAMEGEECCKKCTLTQDSECSDGLCCSNCKFNPKEMLCREAVNDCDIPETCTGNTSQCPANIHKLDGYSCESMQGLCFGGRCKTRDRQCKYIWGEKVSAADRYCYEKLNIEGTEKGNCGRNKETWIQCNKQDVLCGYLLCTNISNVPRLGELDGDVTSSSIVNQGKLYNCSGGHVKLDEDTDLGYVEDGTPCGTGMMCLEHRCLPIDSFNFSTCLGSTNKICSGHGVCSNEVRCICDRFWTGEDCSSYLHYDHIKPEGDNRDEGVISTNIIIGAIAGTILVLALVLGITAWGYKNYRRERQIPQGDYVKKPGDADSFYSDLPPGVSSNSASSSKKRSAILSHFQISACSIPHYSISQNISLFCRRSNGLSHSWSERIPDTKHVSDVCENGRPRSNSWQGNVTSSRKKLRGKRFRPRSNSTETLSPAKSPSSSTGSIASSRRYPYPMPPLPDEERKASKQSARLWETSI
What is the function of this protein?
Probable ligand for integrin in the brain.  This is a non catalytic metalloprotease-like protein (By similarity).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 22, ADAM 22, MDC11.2, Metalloprotease-disintegrin MDC11b.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KAD_CHLT3
Sequence: MKIILFGPPGVGKGTQAKILSEKHQLAHISTGDMLRSAIKQGTELGLKAKSFIDKGELVPDDVIIGMIEEYVSVQENREQGFILDGFPRTVPQAEALDRLLQKYEIPIDCVISLTADAEEIVARLSGRRIAPSTGKVYHVVYNPPKVEGKCDETGEDLIIREDDKEETIRKRLSIYDQTTAPVLDYYKKKGTAAEVDGTQSIDKVSKEIDEILTSATK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KR231_HUMAN
Sequence: MSYNCCCGNFSSHSCEGYLCYSGYSRGGSSYPSNLVYSTEPLISQHLPAGFLSLQGLSGDLLGNP
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 23-1.
Protein: LGT_HELP2
Sequence: MNAWNTIYDQFNPIAFSLGSIEVHWYGLAYACAIVVAFYMALRMIQKDPKRFPIERKEFESYFLWAELGIVLGARVGYILIYEPNSSYYLTHFWQIFNPFDSHGNFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKDSHLGQIIGIMVDHQLRYPSQLIEAFLEGVIVFLMVMWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLFMVIVSLGILLYATKNSKKIKENQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAC20_ORYSJ
Sequence: MGEQQQQVERQPDLPPGFRFHPTDEEIITFYLAPKVVDSRGFCVAAIGEVDLNKCEPWDLPGKAKMNGEKEWYFYCQKDRKYPTGMRTNRATEAGYWKATGKDKEIFRDHHMLIGMKKTLVFYKGRAPKGDKTNWVMHEYRLADASPPPPPSSAEPPRQDDWAVCRIFHKSSGIKKPVPVAPHQVPAAANYQQQQQMAMASAGIIQVPMQMQMPSMSDQLQMLDDFSTTASLSLMAPPSYSTLPAGFPLQINSGAHPQQFVGNPSMYYHQQQQMDMAGGGFVVSEPSSLVVSPQDAADQNNNAADISSMACNMDAAIWKY
What is the function of this protein?
Transcription factor that acts redundantly with NAC26 to regulate the expression of genes involved in the biosynthesis of starch and storage proteins in grain (PubMed:32989010).  Directly binds to the promoters of starch synthase 1 (SS1), pullulanase (PUL), glutelin A1 (GLUA1), glutelins B4 and B5 (GLUB4 and GLUB5), alpha-globulin and 16 kDa prolamin, and activates their expression (PubMed:32989010).
What are the official names of this protein?
NAC domain-containing protein 20, ONAC020, OsNAC20.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: RAD24_SCHPO
Sequence: MSTTSREDAVYLAKLAEQAERYEGMVENMKSVASTDQELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKGNTAQVELIKEYRQKIEQELDTICQDILTVLEKHLIPNAASAESKVFYYKMKGDYYRYLAEFAVGEKRQHSADQSLEGYKAASEIATAELAPTHPIRLGLALNFSVFYYEILNSPDRACYLAKQAFDEAISELDSLSEESYKDSTLIMQLLRDNLTLWTSDAEYSAAAAGGNTEGAQENAPSNAPEGEAEPKADA
What is the function of this protein?
Acts in cell cycle and stress checkpoint signaling by sequestering signal transducers regulated by the checkpoints (PubMed:11818066, PubMed:8036497, PubMed:15629716).  Required for the DNA damage checkpoint that ensures that DNA damage is repaired before mitosis is attempted (PubMed:8036497).  During environmental stress, sequesters srk1-phosphorylated cdc25 in the cytoplasm to delay the G2/M transition (PubMed:15629716).  Sequesters byr2 in the cytoplasm to prevent its translocation to the plasma membrane (PubMed:12242289).  Sequesters ran1/pat1-phosphorylated mei2 from its non-coding RNA activators (including meiRNA), to prevent meiotic induction in vegetative cells and to regulate meiosis I (PubMed:11818066).
What are the official names of this protein?
Checkpoint signal transducer rad24.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_NEOSM
Sequence: MSYVALGVDPGLLRTGWAVVEYDGLCNVRYIDSGIVKTASQGSLSARLEKIHRGISDVIEKVNPSVAVLEKVFVNNNPYSSLNLAYCRGALILTLALKGLFIVEFAPSVLKKRITGNGRATKAQVKYMVEQLLGLDPCLSKYSDLYDALALAASVTRYDIMEAKGT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: VDAC5_ORYSJ
Sequence: MAMKGPGLFSDIGKRAKDLLTKDYTYDQKLTVSTVSSSGVGLTSTAVKKGGLYTLDVSSVYKYKSTLVDVKVDTESNISTTLTVFDVLPSTKLVTSVKLPDYNSGKVEMQYFHENASFATAVGMKPSPVVEFSGTAGAQGLAFGAEAGFDTATGKFTKYSAAIGVTKPDYHAAIVLADKGDTVKVSGVYHLDDKQKSSVVAELTRRLSTNENTLTVGGLYKVDPETAVKARLNNTGKLAALLQHEVKPKSVLTISGEFDTKALDRPPKFGLALALRP
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
What are the official names of this protein?
Mitochondrial outer membrane protein porin 5, Voltage-dependent anion-selective channel protein 5, OsVDAC5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: PPNP_GEODF
Sequence: MSEFSNVTVVKEANIFFDGGVTSRTIIFSSGSKKTLGIMMPGEYVFNTAGAELMEILSGDLEVQIAGIDSWKPVKGGESFEVPASSSFRMKVKTVTDYCCSFLA
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: Y084_STAAC
Sequence: MQRDYLIRVETESMSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRFQLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNELSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEYVGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFARTFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYKEIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKLNAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSHRKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVFDANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFITNGEYFRGGIIIEQLLKLSSKVEGIGYWLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVYFTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLNINALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDITDTLALNIKMITNGIHLIEVKRYPSS
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator SACOL0084.
Protein: RL9_PARP8
Sequence: MQIILLEKVLNVGNLGDIVKVKDGYARNFLIPNKKARRATKEAIAEFEVRRAELEKVAAEKLSAAQAQGEKLSGMTVQIAQKAGVDGRLFGSVTNADIAAALGKQGFEVEKAQVRLPEGPLKMVGDHPVHVSLHTDVTVDVTVSVLGEHV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: KTHY_PSE14
Sequence: MTGLFITLEGPEGAGKSTNREYLAAQLRAQGVQVLLTREPGGTPLAERIRELLLAPSDEAMSADTELLLVFAARAQHLAEVIRPALARGEVVLCDRFTDATYAYQGGGRGLSQQRIAVLEEFVQGDLRPDLTLVFDLPVEIGLSRAAARGRLDRFEQEGRAFFDAVRSTYLQRAKADPARYRLVDAAQPLADVQASLDTLLPQLLELRRG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NKX26_HUMAN
Sequence: MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW
What is the function of this protein?
Acts as a transcriptional activator (PubMed:15649947).  In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.
What are the official names of this protein?
Homeobox protein Nkx-2.6, Homeobox protein NK-2 homolog F.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAP20_MOUSE
Sequence: MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEGSKSEPWAALLRSTVSGTADWTPNRQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEPEGSLGSPTPSLKGCPALNSGRTPSAQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW
What is the function of this protein?
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair.  Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex.  Promotes translesion synthesis via interaction with REV1 (By similarity).
What are the official names of this protein?
Fanconi anemia core complex-associated protein 20, FANCA-associated protein of 20 kDa, Fanconi anemia-associated protein of 20 kDa.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8.
Protein: MDR2_TRIIM
Sequence: MVEVSEKPNTQDDGVSKQENRNPASSSSSTSDKEKVAKKGNSDATKSSTPEDLDAQLAHLPEHEREILKQQLFIPDAKATYGTLFRYATRNDMIFLAIVSLASIAAGAALPLFTVLFGSLAGTFRDIALHRITYDEFNSILTRNSLYFVYLGIAQFILLYVSTVGFIYVGEHITQKIRAKYLHAILRQNIGFFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTALSTFFSAFIIGYVRYWKLALICSSTIVAMILVMGGISRFVVKSGRMTLVSYGEGGTVAEEVISSIRNATAFGTQEKLARQYEVHLKEARKWGRRLQMMLGIMFGSMMAIMYSNYGLGFWMGSRFLVGGETDLSAIVNILLAIVIGSFSIGNVAPNTQAFASAISAGAKIFSTIDRVSAIDPGSDEGDTIENVEGTIEFRGIKHIYPSRPEVVVMEDINLVVPKGKTTALVGPSGSGKSTVVGLLERFYNPVSGSVLLDGRDIKTLNLRWLRQQISLVSQEPTLFGTTIFENIRLGLIGSPMENESEEQIKERIVSAAKEANAHDFIMGLPDGYATDVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTKSEGVVQAALDAASRGRTTIVIAHRLSTIKSADNIVVIVGGRIAEQGTHDELVDKKGTYLQLVEAQKINEERGEESEDEAVLEKEKEISRQISVPAKSVNSGKYPDEDVEANLGRIDTKKSLSSVILSQKRSQEKETEYSLGTLIRFIAGFNKPERLIMLCGFFFAVLSGAGQPVQSVFFAKGITTLSLPPSLYGKLREDANFWSLMFLMLGLVQLVTQSAQGVIFAICSESLIYRARSKSFRAMLRQDIAFFDLPENSTGALTSFLSTETKHLSGVSGATLGTILMVSTTLIVALTVALAFGWKLALVCISTVPVLLLCGFYRFWILAQFQTRAKKAYESSASYACEATSSIRTVASLTREQGVMEIYEGQLNDQAKKSLRSVAKSSLLYAASQSFSFFCLALGFWYGGGLLGKGEYNAFQFFLCISCVIFGSQSAGIVFSFSPDMGKAKSAAADFKRLFDRVPTIDIESPDGEKLETVEGTIEFRDVHFRYPTRPEQPVLRGLNLTVKPGQYIALVGPSGCGKSTTIALVERFYDTLSGGVYIDGKDISRLNVNSYRSHLALVSQEPTLYQGTIRDNVLLGVDRDDVPDEQVFAACKAANIYDFIMSLPDGFGTVVGSKGSMLSGGQKQRIAIARALIRDPKVLLLDEATSALDSESEKVVQAALDAAAKGRTTIAVAHRLSTIQKADIIYVFDQGRIVESGTHHELLQNKGRYYELVHMQSLEKTQ
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds, including terbinafine, 4-nitroquinoline N-oxide, and ethidium bromide (PubMed:16849730).  May play a role in pathogenicity (PubMed:19141731).
What are the official names of this protein?
ABC multidrug transporter MDR2, Multidrug resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CARA_THEAC
Sequence: MKRYLITSDGTVIAGYGYGSPVTGYGELVFTTSMTGYLESMTDPSYVGQILVFASPTIANYELRKGVMESDRVKVSGIVTRDAHINMPAGTLGLDFDRFLRDEGIPAIDGVDTRLLVRKIRQGGVLRAYIADDPQGHSDFPDPMSENLVARAVDARGVKNIRGKGERRILFIDLGSKKTLRDMMLEHFSLIMASADSDLDAIDKYDAIFVSNGPGDPDHPSLRPVVNFLKRNIGVKPIFGICFGLQIIALAYGSKTYKMKFGHRGSNHAVTDGNRIYVTTHNHGYAVDPDTVRDFHVRERDINDGTIEMIEDGMMMAVQYHPEASPGPHDTRWFFSEMRRRTEDAAKG
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: MCSB_STAAB
Sequence: MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYATENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDESLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLTLGKSELEIIETLTEVVNQIIHEEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITMEEASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHIK
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: MYO1_ASPCL
Sequence: MGHSRRPVGGEKKSRGFGRSKAAADVGDGRQAGKPQVKKAVFESTKKKEIGVSDLTLLSKISNEAINDNLKLRFEHDEIYTYIGHVLVSVNPFRDLGIYTDNVLESYRGKNRLEVPPHVFAVAESAYYNMKSYKDNQCVIISGESGAGKTEAAKRIMQYIASVSGGTDSSIQQIKEMVLATNPLLESFGNAKTLRNNNSSRFGKYLELEFNTNGEPVGANITNYLLEKSRVVGQITNERNFHIFYQFTKAAPQKYRDMFGIQQPQSYLYTSRSKCYDVPGIDDSAEFRDTVNAMNVIGMTESEQDNVFRMLAAILWIGNVQFAEDDSGNAAITDQSVVDFIAYLLEVDAAQVNKAFTIRVMETARGGRRGSIYEVPLNTVQALAVRDALAKAIYFNLFDWIVQRVNSSLAARGEIANSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKAEQDEYAREQIQWTPIKYFDNKVVCSLIEDKRPPGVFAALNDACATAHADSGAADNTFVGRLNFLSQNPNFENRQGQFIVKHYAGDVSYAVTGMTDKNKDQLLKDLLNLVGSSGNQFVHTLFPEQVNQDDKRRPPTASDKIKASANDLVATLMKAQPSYIRTIKPNDNKAPREYNVGNVLHQIKYLGLQENVRIRRAGFAYRQTFDKFVERFYLLSPKTSYAGDYTWTGSAESGARQILKDTSIPAEEYQMGITKVFVKTPETLFALEAMRDRYWHNMAIRIQRAWRNYLRYRIECATRIQRFWRRTTGGLEFIKLRDQGHQLLNGRKERRRMSLLGSRRFLGDYIGVGNKGGPGEMVRNGAGISGSEDILFSCRGEVLVSKFGRSSKPAPRILVLTNRHIYIIAQNILNNQLVISSERTIPIGAIKAISASNLKDDWFSIVVGSAQEPDPLLSCVFKTELFTHLNNALRGQLNLKIADHIEYSKKPGKMATVKVVKDPAVTGDDTYKSSTIHTGAGEPASSVSKPTPRPKPVSARPVTKGKLLRPGGPGGGPSKLASRPTPAAQPLPRATPQPAAAQPAAPQPAARVVPQPVAAVAASHARTGSTASVRAPPPPPPAAAPAPKKPTAKALYDFNSQQPNELSIKAGEIVQIVSKEGNGWWLCMNMATSSQGWTPEAYLEEQVAPAPKPTPPPPPPAAPRSTPTPVNGAAAAAKAKPAPPAPPAKRPNMAGRKAVPAPPPAPRDSAVSMNSHDSSGGSGRGTPNSASNASLAGGLAEALRARQHAMQGKNDDDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex.  Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Localizes to cortical patch-like structures. Enriched at sites of polarized growth, like the growing hyphal tips and sites of septum formation (By similarity).
Protein: RL16_SHIBS
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.