PharMolix/UniProtQA huggingface dataset:
Protein: ATG1_PODAS
Sequence: MADRQLSSASSSRRQKQPTDGAVGQFVIDKEIGKGSFAQVYSGRHKVTGALVAIKSVELSRLNKKLKENLYGEIKILKTLRHPHIVALHDCVESATHINLIMEYCELGDLSLFIKKREKLITHSATRDIARRYPIEHNQGLHEVITRHFLKQLASALKFLREGNFVHRDVKPQNLLLLPSPLFRETHHSAKQILSASYDSLMPAAGLPSLPMLKLADFGFARVLPSTSLAETLCGSPLYMAPEILRYERYDAKADLWSVGTVLYEMATGRPPFRAGNHVELLRKIEAAEDQVKFPRESVVSPELKSLVRALLKRNPVERISFADFFNHTVITGPIPNLHEDDLPKPEPQQVKETVRPEGSLSLSRRDSQRGKAATGVLSSPRPRPSSPLATPIEKPNPLEQVPGPRAGLSYSPAGDGLGITRRPAVQPSTSAPARPVMYVDRSRANSTASQRPPRESIVPDPSQTLASQPRPKSRPTKPLTEEEKAAQDVALERDYIFIDKKGVEVNALADQISMYPQSVPKSGQIVRRATQQGHPTSTTGAVSARNNHLRQGSYDKPLSSSPGSTTSAISKAIQDASLRLFGFNVAPHLLSKGQSPPQIYSPFPAYPTPSAPAGLISDGKHTTPVDEDSRVAQCIEDWATRSDVVYGFAEVKYKQLVPLAPSMDYGLGGVPADKMEEEDGLTLEATVSLSEEALVLYVKALSLLAKSMDIASLWWTRKSRSDNSNSIHSAARDSVNSQALALKINRVVQWIRSRFNEVLEKAEIVRLKLIEAQKQLPEDHPSHPSNHQTEVSSVTGAEGVILSPGISAEKLMYDRAVEMSRTAAINEIASEDLPGCEIFYSTAIRMLEAVLDSDDDHLPKRRISTSSRDEKAEAAVREDTSEMSSEDKQSIQKMIQMVKARLANLQKKMLAISRAQQQQQQDIISVRRRSGEMAPRSVPV
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes (PubMed:16278443).  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: LLDD_AGRVS
Sequence: MIISSSTDYREAARRRLPPFLFHYIDGGAYSEHTMRRNIDDLADLALRQRVLKSVGTVDISTTLFDEELAMPVVLAPVGLTGMYARRGEVQAARAAEKKGIPLTLSTVSVCPIEEVQAASNRPIWFQLYVLRDRGFMKNALERAWAAGIRKLVFTVDMPVPGARYRDAHSGMSGPNASLRRIIQAVMHPTWAIDVGLLGKPHDLGNVSAYRQQKTNLADYVGWLGENFDPSIGWKDLEWIRDFWKGPMIIKGILDPEDAKDAVRFGADGIIVSNHGGRQLDGVLSSARALPAIAAAVKGDLTILADSGIRSGLDVVRMIAQGADGVLIGRAFVYALAAAGQAGVENLLDLFAKEMRVAMTLTGARSIAEISPDSLVRGL
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C90B2_ORYSJ
Sequence: MAAMMASITSELLFFLPFILLALLTFYTTTVAKCHGGHWWRGGTTPAKRKRMNLPPGAAGWPLVGETFGYLRAHPATSVGRFMEQHIARYGKIYRSSLFGERTVVSADAGLNRYILQNEGRLFECSYPRSIGGILGKWSMLVLVGDPHREMRAISLNFLSSVRLRAVLLPEVERHTLLVLRAWPPSSTFSAQHQAKKFTFNLMAKNIMSMDPGEEETERLRREYITFMKGVVSAPLNLPGTPYWKALKSRAAILGVIERKMEERVEKLSKEDASVEQDDLLGWALKQSNLSKEQILDLLLSLLFAGHETSSMALALAIFFLEGCPKAVQELREEHLGIARRQRLRGECKLSWEDYKEMVFTQCVINETLRLGNVVRFLHRKVIKDVHYKGYDIPSGWKILPVLAAVHLDSSLYEDPQRFNPWRWKSSGSSGGLAQSSSFMPYGGGTRLCAGSELAKLEMAVFLHHLVLNFRWELAEPDQAFVFPFVDFPKGLPIRVHRIAQDDEQE
What is the function of this protein?
Catalyzes the C22-alpha-hydroxylation step in brassinosteroid biosynthesis, which is the rate-limiting step in this biosynthetic pathway (PubMed:16369540).  Catalyzes the conversion of campesterol (CR) to (22S)-22-hydroxycampesterol (22-OHCR, 22-hydroxyCR) and of campestanol (CN) to 6-deoxycathasterone (6-deoxoCT) (PubMed:16369540).  Required for auxin responses involved in the regulation of epidermal cells length of the lamina joint (PubMed:19605414).
What are the official names of this protein?
Steroid (22S)-hydroxylase, (22S)-22-hydroxycampesterol synthase, 6-deoxycathasterone synthase, Cytochrome P450 90B2, OsCYP90B2, Protein DWARF4 homolog, OsDWARF4, Steroid 22-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: G3P_HYPBU
Sequence: MARVRVGVNGFGTIGKRVAEAIMLQPDMELVGVTKTKPDYTAKYAVSRGIPVYVPKESLEEFQAKGIEPAGTIEELLEKVDVIVDATPGGTGRKYKPLYEKAGVKMIFQGGEKADIAELSFSTLCNYEQALGKTSLRVVSCNTTGLLRAICSISRLAPVRRVRATIVRRAADPKEIKRGPVNAIKPDPVKTPSHHALDVKTVLPDLDIVTMAVVVPTTLMHVHIVYAELEKPVTREDVVATFESTPRILLADASYGLASTAELVEYARDLGRKRYDIPELIVWLDSIAVNGVEVMWMQAVHQEAIVVPENIDAIRAVAELAKTAEETIRITDERLGLLKGRIP
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_SACS2
Sequence: MFRTHLVSELNPKLDGSEVKVAGWVHNVRNLGGKIFILLRDKSGIGQIVVEKGNNAYDKVINIGLESTIVVNGVVKADARAPNGVEVHAKDIEILSYARSPLPLDVTGKVKADIDTRLRERLLDLRRLEMQAVLKIQSVAVKSFRETLYKHGFVEVFTPKIIASATEGGAQLFPVLYFGKEAFLAQSPQLYKELLAGAIERVFEIAPAWRAEESDTPYHLSEFISMDVEMAFADYNDIMALIEQIIYNMINDVKRECENELKILNYTPPNVRIPIKKVSYSDAIELLKSKGVNIKFGDDIGTPELRVLYNELKEDLYFVTDWPWLSRPFYTKQKKDNPQLSESFDLIFRWLEIVSGSSRNHVKEVLENSLKVRGLNPESFEFFLKWFDYGMPPHAGFGMGLARVMLMLTGLQSVKEVVPFPRDKKRLTP
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNF8_YEASV
Sequence: MVKKNFIPSVSLVRRDLPTLVTTTTSSTALSKPTSSVVSETSSKSLPSLTSSAFSTSSGATSSSSLIVASITPPSTAGNPFILNAADKPNGTVYIAVGAVIGAIFISILIWWLVSSYLSRRFTMTNSYANDSKNLYRGHHKHSSSLQSNPFDINDEKSYMQDDWDSMSQLESSQYEDAASPFNPIQDPFTDXRRSLFISPTLQVSQYEKSHSRHQSKDTNIFIDDPSLYVGTYLEEEEEEERKLNLNRPQRAASPERKEKKINSMEGYHKRNQSSLGLIPVASATSNTSSPKKAHKRQAPSMFLDDVLNGREII
What are the official names of this protein?
Vacuolar membrane protein VIN13_4115.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: CCME_POLAQ
Sequence: MKPRHKRALMIVAALAVIGIAALLILNALNSNIALYVTPSDVVAGKAPQGQAFRIGGLVKEGSLKRDGLTVHFVITDLVKDIPVSYTGILPDLFKEGKGAVIQGNLNPQGEFIASEVLAKHDENYMPPEAKHALEQAQKNGSAK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CAP2_ARATH
Sequence: MAPSIRKAIGAVKDQTSIGIAKVASNMAPDLEVAIVKATSHDDDPASEKYIREILNLTSLSRGYILACVTSVSRRLSKTRDWVVALKALMLVHRLLNEGDPIFQEEILYSTRRGTRMLNMSDFRDEAHSSSWDHSAFVRTYAGYLDQRLELALFERKSGVSVNSGGNSSHHSNNDDRYGRGRDDFRSPPPRSYDYENGGGGGSDFRGDNNGYGGVPKRSRSYGDMTEMGGGGGGGGRDEKKVVTPLREMTPERIFGKMGHLQRLLDRFLSLRPTGLAKNSRMILIALYPVVRESFKLYADICEVLAVLLDKFFDMEYSDCVKAFDAYASAAKQIDELIAFYNWCKETGVARSSEYPEVQRITSKLLETLEEFVRDRAKRGKSPERKEIEAPPPVVEEEEPEPDMNEIKALPPPENYTPPPPPEPEPQPEKPQFTEDLVNLREDEVTADDQGNKFALALFAGPPGNNGKWEAFSSNGVTSAWQNPAAEPGKADWELALVETTSNLEKQTAALGGGFDNLLLNGMYDQGMVRQHVSTSQLTGGSASSVALPLPGKTNNQVLALPAPDGTVEKVNQDPFAASLTIPPPSYVQMAEMEKKQYLLSQEQQLWQQYQRDGMRGQASLAKMNTGPVPAYGMPPVNGMGPPPTGYYYNNPY
What are the official names of this protein?
Putative clathrin assembly protein At2g25430.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: HIS4_BURM1
Sequence: MLLIPAIDLKDGQCVRLKQGDMDQATIFSEDPAAMARKWVDLGARRLHLVDLNGAFAGKPKNLDAIEAILDEVGDEIPVQLGGGIRSLETIEKYLDAGLSYVIIGTAAVKDPGFLRDACTAFQGNIIVGLDAKDGKVATDGWSKLTGHEVIDLAQKFEDYGVESIVYTDIGRDGMLQGINIDATVKLAQAVGIPVIASGGLSNLEDIDKLCEVEEEGVEGVICGRAIYSGDLDFAAAQRRADELNGELDDA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM33_CONLT
Sequence: MLKIGVVLFTLLVLFPLATLQLDADQPVERYAENKQDLNPNERMKMIMSALGQRRCCISPACHEECYCC
What are the official names of this protein?
Conotoxin Lt3.3, Lt3c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VF152_ASFB7
Sequence: MYSILIACLVLLLCLVIYVGHRADHARKYLEGMWHGDPVFLKQSGLQSFYLYIQPGHTCFFSIVNKNGEKLMETKIPCTITNKIYMFFKPIFEFHVVMEDIHRYLPKQFNFLLDSAEGKLILENNHVIYAVLYKDNFATALGKTVEKYITQN
What are the official names of this protein?
Uncharacterized protein EP152R, pEP152R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus EP152R family.
What are the subcellular locations of this protein?
Virion.
Protein: SHOC2_DANRE
Sequence: MSSTLGKDKDSKEREPKAEGKSKTKGKDAKDGKKDTSGASPAVAFTLDSTIKRPNPPPSTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
What is the function of this protein?
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation.  Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of raf1 kinase and stimulate raf1 activity at specialized signaling complexes (By similarity).
What are the official names of this protein?
Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein sur-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SELO_PECCP
Sequence: MQQTPLFKNHYFHQLPEFYTALQPKPLHGARLLYHSEGLAAELGLSSDWFTPEQDAVWSGERLLPGMEPLAQVYSGHQFGMWAGQLGDGRGILLGEQQLADGRSMDWHLKGAGLTPYSRMGDGRAVLRSVIREFLASEAMHHLGIPTTRALTIVTSTHPVQREQEEKGAMLMRVAESHVRFGHFEHFYYRREPEKVRQLVEYVIARHWPQWENDERRYELWFGDVVERTARLITHWQAVGFSHGVMNTDNMSILGLTIDYGPYGFLDAYQPNFICNHSDHRGRYAFDNQPAVGLWNLHRLAQALSGLMDTDTLERALARYEPALMQHYGTLMRAKLGLFTASAEDNDVLVGLLRLMQQEGSDYTHTFRLLADSEKQASRAPLRDEFIDRAAFDSWFATYRQRLMQEEQGDEERRRLMNTTNPKFILRNYLAQMAIERAENDDISVLARLHQALCQPFDEQPDKNDLAALPPEWGKHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PNK1_SCHPO
Sequence: MSSKKRKSPPQESLTSYFEKSSKSSKKYGSQNKDSDSSSTCLQQKIEIQWSITDSLYIAKYGKLKKTKKFIAFDLDGTLIKTKSGRVFSKDAADWTWWHPSVVPKLKALYQDNYSLVIFSNQNGIPRKPSAGHTFQMKIRAIFESLDLPIVLYAAILKDKFRKPLTGMWNSFLKDVNRSIDLSFIKYVGDAAGRPGDHNSTDLKFAENIGIKFETPEQFFLGHSFVPPNFESFHPKNYLVRNSSSHPYHFKKSEHQEIVVLVGFPSSGKSTLAESQIVTQGYERVNQDILKTKSKCIKAAIEALKKEKSVVIDNTNPTIESRKMWIDIAQEFEIPIRCIHLQSSEELARHNNVFRYIHHNQKQLPEIAFNSFKSRFQMPTVEEGFTNVEEVPFKCLKDYEDTWNYWYE
What is the function of this protein?
Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini.  Has a role in the repair of breaks in single-stranded DNA.
What are the official names of this protein?
Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the DNA 3' phosphatase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XKDF_BACSU
Sequence: MARELRNAKISFVSYVDKAANQTEFFFTKSAEPPSFEKKVRLFTKSEQDEQKLVYGIVYEPDVPDAHGDFMTAEEIEKAAHGFLAEAREIDINHSFEGGTGVVVESYVAPDDFMIGSKRITKGSWVLVTRASDEVWEQIKAGIITGYSMAGTADVYEEEPVEKAGFFSVFKQMLADKTGKETEEMRKEDMKESFEHALYPLLKRLERIEKNTDTEEKPEQTGDDERLKKLVEDMLAPLIERIEALEKARGASKQTADDTGGNTEQVKKSIWSGLL
What are the official names of this protein?
Phage-like element PBSX protein XkdF.
What is the protein family that this protein belongs to?
To B.subtilis YqbD.
Protein: LDOC1_PANPA
Sequence: MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDDEEEDDY
What is the function of this protein?
May have an important role in the development and/or progression of some cancers.
What are the official names of this protein?
Protein LDOC1.
What is the protein family that this protein belongs to?
Belongs to the LDOC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APSD_AGRRK
Sequence: MNMTELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes oxidation of D-apiose to D-apionolactone.
What are the official names of this protein?
D-apiose dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: ERPA_BURCM
Sequence: MNAVTESAATTAEMPVPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVMNKNGVQLLIDSMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RS15_SORC5
Sequence: MLHSVQKTDIIQKYAIHDGDTGSPEVQIALLSERINQLQEHFRTHQKDHHSRRGLLKLVSQRRRQLDYLKRVDIERYRSLINRLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: METK_PASMU
Sequence: MSRYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRQVICDIGYKHSDMGFDGHSCAVLNAIGKQSSDINQGVDRENPLDQGAGDQGIMFGYATNETEVLMPAAITYAHRLMERQAKVRKEGTLPWLRPDAKSQVTLKYEDHKIVGVDAVVLSTQHCDSISQHDLHEAVMEEIIKPVLPAEWLSKETKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVADPTSIMVETFGTGKVANELLVALVREFFDLRPYGLIKMLDLIQPIYRETAAYGHFGREQFPWEKVDRAEELRAAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMP_PSEPK
Sequence: MLNAEQRAIIKATVPLLESGGEALTTHFYKMMLSEYPEVRPLFNQAHQASGDQPRALANGVLMYARHIDQLEQLGGLVGQIINKHVALQILPEHYPIVGSCLLRAIEEVLGKDIATPAVIDAWGAAYGQLADILIGAEENLYKEKEEAEGGWRGTREFRLVRREQESSEIVSFYFAPVDGMPVLKAEPGQYIGLKLDIDGAEQRRNYSLSALCDGKEYRISVKREAGGKVSNYLHDELKVGDTLQLFPPAGDFTLAASDKPLVLISGGVGITPTLAMLQAALQTRREVHFIHCARNGAVHAFRDWIDGLAARHPQLKRFYCYAEPEGGAAADAVGLLSEDLLAEWLPQERDVDAYFLGPKGFMAAVKRQLKGLGVPEQQSRYEFFGPAAALE
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: RPOB_DEHM1
Sequence: MVSMLPKADAATGITRKSYAQLPEVVNVPNLIEMQLQSFVWFQEEGLRELIEEISPIKDFVGNRLELEFIGYEFREPRLSEYECTQRDQTYSVPLYVKARLIVKTTGEIKEPFDLFFGDIPLMTALGTFITSGTERVVVSQLLRSPGVYFTISDDPATGRPLCHTNLIPSRGAWLEFETSNRDVISVKIDGRRKIPVSTLLRAIGYSDDLDILNLFEVIDNDPERHYIQSSIDRDPLIKDEISALIDIYSRLRPGDPPNADNARKLINEMFFDPQHYDLGKVGRYKVNRRLELPDREVGDNRALTREDIVAIIKRIIMVNNGQDTPDDIDHLGNRRIRTVGELVQNQFRIGLVRLERVARERMSIVNLEVVTPSALVNIRPVVSAVKEFFGGSQLSQFMDQTNPLAEITNKRRLSAMGPGGLSRERAGFDVRDVHYSHYGRICPIETPEGPNIGLIGSLATYSRINRYGFVETPYRKVYSKLKNNDKKLVGLKLAAAVSDKDKVLASAGSVVSEENFKLISKLPECDIQVMPFVSAEVKYMPADEEDRYIIAQANTRLDENGYFLDERIEARLAERYVIEPPEKIDYMDVSPKQIFSVAASLIPFLEHDDANRALMGANMQRQAVPLLRAEAPMVATGMEREAARYSGQVIFAKRAGVAASVTSEKIIIRTAEGQDDEYLLKKFVRTNQGTCINQHAVINKGQKIEAGQVLADSSATENGELALGQNCVVAFMSWQGFNYEDAIILSERLVREDAFTSIHITKHELEAHDTKLGGEEITRDIPNVGEESLRELDEDGIIRIGAEVGPDDILVGKITPKGETELSAEEKLLRAIFGEKAREVKDTSLRMPHGEWGKVINVRVFSRENGDDLPARVNKWVQVWVAQKRKVSVGDKLAGRHGNKGVISIIAPVEDMPYLPDGTPVDVVLNPIGVPSRMNLGQILETHLGWAGHLLGFRVATPVFDGADDTAIEDALARSWLSAKAGATDMSPENKRPSTDTAKAVEWIKQQGFDGKKVFDERHPGLAKEVSLKLWLKDMGVDASSLSGAELEKKAYEVSSQSRLPSPIVGKSVLRDGRTGETFDQPVTVGNMYILKLIHLVEDKVHARATGPYSLISQQPLGGKAQFGGQRFGEMEVWAMYAYGTAHNLQEMLTIKSDDIAGRAKAYESIVKGEDVIQPGVPESFKVLVKELQSLGLAVEVINEEVKIAPSEKVAALTEANLPGSEDVSAEILPETLYAGAEDIEDSMMSVIDTDDQDLAMSSNDEEVSENDERS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DAD1_HUMAN
Sequence: MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:22467853, PubMed:31831667).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes.  Loss of the DAD1 protein triggers apoptosis (PubMed:22467853).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMG_SYNJB
Sequence: MKKADAPSSEPPELKALWESWLADLGWQPSEQQQQQLQQLYPLVMAGNRTQNLTRITDPIDFWEKHLWDSLRGLRLLGSWEAIQAQPWRGIDIGTGAGFPGIPAQIALPQTRFTLLDSTQRKIAFVQDILQRLSLTQARAVAQRAEIWGQDPQERGSYDIALARALASAEICAEYCLPLLKVGGRAILYRGHWTEAEAQTLEQALELLGGKLIHVEAFTTPRSRGVRHCLLLEKVAPTPPPYPRSPGTPKRQPLGQSNRP
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.