PharMolix/UniProtQA huggingface dataset:
Protein: IRAP_SALHS
Sequence: MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_YERP3
Sequence: MNPIVINRLQRKLGYTFQQQELLLQALTHRSASSKHNERLEFLGDSILSFVIANELYRRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIHTIERLILEWYHSRLEEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLNEPVIGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_STRA1
Sequence: MTKEVVVESFELDHTIVKAPYVRLISEEVGPVGDIITNFDIRLIQPNENAIDTAGLHTIEHLLAKLIRQRINGLIDCSPFGCRTGFHMIMWGKQDATEIAKVIKSSLEAIAGGVTWEDVPGTTIESCGNYKDHSLHSAQEWAKLILSQGISDNAFERHIV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NFUA_PSEP1
Sequence: MSAITITDAAHDYLADLLSKQNTPGIGIRIFITQPGTQYAETCIAYCKPGEEKPDDTAVGLKSFTAYLDAVSVPFLEDALVDYATDRMGGQLTIKAPNAKVPMVNEDSPINERINYYLQTEINPGLASHGGQVSLVDVVDDGIAVLQFGGGCQGCGQADVTLKEGIERTLLERIPELKGVRDVTDHSQKENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: CAPSD_PCV87
Sequence: MSNIAEVSRGGGHYGVDPWRQHIIKNRINADWWIRLDHWETLLADLRGVSFEVNSSRSQVADFINRVPKDLPAGVSVRFPGPRGNLGSTNYTEVYFVRIKSELKQKLLSLIAAADQGKNRDVEIGRPNAPVVSTGAGGNQAIVAQRGVNTVRDQQPLRDGSLHYRYLVQDIELAGAEQFDRALFEETFSLNWTVVAPPAGGGGGGAP
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 25 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein, P23.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: PTH_SHIDS
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVVHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAVRCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP1_CAEEL
Sequence: MLRNGSLRQSLRTLDSFSLAPEDVLKTAIKTVEDYEGDNIDSNGEIKITRDAKEEVVNKVSIPQLYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGKVSQAFINEQIVINNNGSTFLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMWAAGQITVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLVTAQTFTDAVDSAAEGKFSRENSVARQTSEHEGLSRQASEMDDIMNRVRSSTIGSITNGPVIDEKEERIGKDALSRLKQELEENNAQKTNLFEILYHARPHALSLFIGMSTATIGGFIYPTYSVFFTSFMNVFAGNPADFLSQGHFWALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRMGLALIITDPPTMQPMRVLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKLTQKQMTEKK
What is the function of this protein?
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
What are the official names of this protein?
Multidrug resistance protein pgp-1, P-glycoprotein A, P-glycoprotein-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RAPA_YERPY
Sequence: MPFTLGQRWISDTESELGLGTVVAIDVRMITLLFPATGENRLYARNDSPITRVMFNPSDTITHHEGWQLKVEEVTQENGLITYIGTRLDTEETGVAMREVLLDSKLTFSKPQDRLFAGQIDRMDRFALRFRARKYQSEQFRLPWSGLRGIRASLIPHQLHIAYEVGQRHAPRVLLADEVGLGKTIEAGMIIHQQLLAGRAERVLIVVPESLQHQWLVEMLRRFNLRFSLFDDSRYSEALLDSSNPFDTEQMVICSLDFVRRNKQRLEQLADASWDLLVVDEAHHLAWSEEAPSREYQVIEQLAEHIPGVLLLTATPEQLGQQSHFARLRLLDPDRFHDYEEFVNEQQKYRPIADAVTLLLGGERLTDDKLNLLGELIDEQDIEPLLKAANSQSEDSEAARQELVTMLMDRHGTSRVLFRNTRNGVKGFPHRVLHQIKLPLPTQYQTAIKVSGIMGAKKTLDARAKDMLYPEQIYQEFEGENATWWNFDPRVEWLLNYLVANRGEKVLVICAQAATALQLEQVLREREAIRAAVFHEGLSLIERDRAAAYFASEEDGAQVLLCSEIGSEGRNFQFACQLVMFDLPFNPDLLEQRIGRLDRIGQNREIQIMVPYLEDTAQAILVRWYHEGLDAFEHTCPTGRTIYDSSYQELISYLATPSEQEGLDEFIHTCRQQHEGLKLQLEQGRDRLLEMHSNGGEHGQELAQSIAEQDNDINLVSFALNLFDIVGINQEDRSDNLIVLTPSDHMLVPDFPGLPPDGCTVTFDREQALSREDAQFVSWEHPIIRNGLDLILSGDTGSCAVSLLKNKALPVGTLLAELVYVVEAQAPKHLQLTRFLPPTPVRMLMDRNGTNLAAQVEFESFNRQLNAVNRHTSSKLVNAVQQEVHTMLQQAEALVEAQAQALIETAKREADDKLSTELARLEALKAVNPNIRDDEIEALEHNRKMVLENLNQAGWRLDAIRLVVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: APY2_ORYSJ
Sequence: MRRYSALPGGGARPDTLADRLHRYRGVLLVILAPLALVSLVLLLMPRSPASSSAAAGRRWGPLDANKYAVIFDAGSSGSRVHVFRFDANLDLLHIGDQIELFVQKKPGLSEYANNPQEAAKSLVSLLEDAKRVVPVELRGQTPVRVGATAGLRALGAEKSEEILQAVRDLLREKSSFKTQPDWVTVLDGPQEGAYEWVTINYLLGKLGKTYADTVGVVDLGGGSVQMAYAIAEKDAVKAPKPSEGEDSYVKKLFLKGTTYYLYVHSYLHYGLLAARAEILKAGNGKGYSYCTLEGHQGQYKYGNGKFEASASPSGASYSKCRDDVVKALKVDQACTHMKCSFGGIWNGGGGAGQKNLFVASFFFDRAAEAGFVNPKAPVAKVKPSDFEKAAKRACKLNLKDAEAAYPGVQKDNIPYICMDLVYQYTLLVDGFGVGSHQEMTLVKKVPYSNAFVEAAWPLGSAIEVAS
What is the function of this protein?
Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.
What are the official names of this protein?
Probable apyrase 2, OsAPY2, ATP-diphosphatase, ATP-diphosphohydrolase, Adenosine diphosphatase, ADPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL33_AZOSB
Sequence: MAKGIREKIKLESTAGTGHFYTTSKNKRTTPEKLEFNKYDPVARKHVPYKEVKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: AT11C_MOUSE
Sequence: MFRRTLNRLCAGEEKRVGTRTVFVGNHPISGTEPYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSAVYIIENAKRVRKESEKIKVGDVVEVQANETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDNLRATIECEQPQPDLYRFVGRISIYSNSIEAVARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKCSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSSPYNDEPWYNQKTQKERETFQVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGTTQEVDGLSQTDGPLAYFDKADKNREALFLRALCLCHTVEMKTNDDVDGPVEGAGFTYISSSPDEIALVKGAKRFGFTFLGNQNGYIRVENQRKEIEEYELLHTLNFDSVRRRMSVIVRTQKGDILLFCKGADSSIFPRVHSHQIELTKDHVERNAMDGYRTLCVAFKEIPPDDFERINAQLVEAKMALQDREEKLEKVFDEIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLVHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTADPRLYMKITGNAMLQLGPFLHWTFLAAFEGTVFFFGTYFLFQTSSLEDNGKIYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLCSVSTWLAIILLIFISLFPEILLIVVKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNIL
What is the function of this protein?
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane (PubMed:24904167, PubMed:26799398, PubMed:30018401, PubMed:24898253).  Major PS-flippase in immune cell subsets (PubMed:30018401).  In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface.  This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages (PubMed:24898253).  Required for B cell differentiation past the pro-B cell stage (PubMed:21423173).  Seems to mediate PS flipping in pro-B cells (PubMed:21423172, PubMed:26799398).  May be involved in the transport of cholestatic bile acids (PubMed:21518881).
What are the official names of this protein?
Phospholipid-transporting ATPase 11C, ATPase class VI type 11C, P4-ATPase flippase complex alpha subunit ATP11C.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A. Internalized via clathrin-dependent endocytosis in response to ca(2+) signaling induced by G-protein coupled serotonin and histamine receptors, HTR2A and HRH1 respectively.
Protein: DEGPL_BRUME
Sequence: MSRARISNYRKGVAAVALSAALAGAFVVTGPLGALNEARAEAVHVTPPQQAGFADLVEKVRPAVVSVRVKKDVQETSNRGPQFFGPPGFDQLPDGHPLKRFFRDFGMEPRGDSRSDNRRGKANKPRPGHERPVAQGSGFVISEDGYVVTNNHVVSDGDAYTVVLDDGTELDAKLIGADPRTDLAVLKINAPKRKFVYVAFGDDNKVRVGDWVVAVGNPFGLGGTVTSGIVSARGRDIGAGPYDDFIQIDAAVNKGNSGGPAFDLSGEVIGINTAIFSPSGGSVGIAFAIPSSTAKQVVDQLIKKGSVERGWIGVQIQPVTKDIAASLGLAEEKGAIVASPQDDGPAAKAGIKAGDVITAVNGETVQDPRDLARKVANIAPGEKAALTVWRKNKAEEINVTIAAMPNDKGKSGSQSNDNDGGQGETLDSYGLTVVPSEDGKGVVVTDVDPDSDAADRGIRSGDVIVSVNNQTVKTAGDINKAITAAEKSGRKAVLLQLQSNDQSRFVALPINQE
What is the function of this protein?
Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
What are the official names of this protein?
Probable periplasmic serine endoprotease DegP-like, Protease Do.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ARLY_CLOK5
Sequence: MKLWGGRFKKSESKLMEDFNSSLSFDRQLYKEDIEGSMVHVKMLAKCNILSSEESKAILSGLESILKDIEEGKLEVEGDYEDIHSFVEINLIERIGQVAKKLHTARSRNDQVALDFRLYAKRKALEVVENIEYLQDVIENLGDKNNVIMPGYTHLQRAQVVTFKHHIMAYYHMFKRDRERILNAICIMDESPLGCCALAGTTYNIDRNFTAQELGFKKPVDNFLDGVSDRDYVIELISDFSIIMMHLSRLSEELILWSSKEFDFIRIDDEFSTGSSIMPQKKNPDAAELIRGKTGRVYGSLVSLLTTMKGIPLAYNKDMQEDKEQLFNSLDTVLSCLKIMSGMLSTLKVNEKNTFNAVKKGFLNATEAADYLVNKGMAFRDAHKVIGEIVLYCEDKNRAIEDISLDELKKFSSLFEEDVYDFIDYENTINRGIKRNLK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_VIBCH
Sequence: MSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSHLSMEERVKTNYDHPSALDHDLLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQERGRTMESVLKQYQETVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_PSYA2
Sequence: MQYPKNYDVVVIGGGHAGTEAALAAARMGAQTLLLTHNIETLGQMSCNPAIGGIGKSHLVREIDALGGAMALATDKSGIQFRVLNSRKGAAVRATRAQADRILYKAAIRHTLENQPNLDIFQQAADDILVENGRATAVVTATGIIFNTQTVVLTSGTFLGGVIHIGLESSKGGRAGDQPSIKLADRLRELKLPVGRLKTGTPARIDARSVDFSVMAVQPGDTPLPVMSYMGDVSMHPEQVNCYITHTNARTHDIIRENLDRSPMFSGKIEGVGPRYCPSIEDKIHRFADKDSHQIFIEPEGLTTHELYPNGISTSLPFDVQLEFIHSMKGLENAHITRPGYAIEYDYFDPQNLKPTLETKSIDRLYFAGQINGTTGYEEAGVQGLLAGTNAALVTCENSEFDVWTPRRDEAYLGVLVDDLITHGTTEPYRMFTSRAEYRLLLREDNADQRLTETGRKLGLVDDVRWQAYEEKMEAIASETSRLKDIWATPINALGAQVTAQTGEVLSKESTAYDLLKRPQIHFNDIAAITGSEVDSQVGEQIEISVKYAGYIDRQQEDIDQMKRLENTALPMDFDYSVVSGLSNEIVQKLAQVRPSTLAQAGRISGVTPAAIQLLAMTVKKQKKVQAALNAS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMUR_BACSU
Sequence: MNKYEIIANEMRNRIKNNVYPIDQPIPDEVSLAKEFNSSRMTMKRALDNLVAEGLLFRKRGHGTFIIQSAIQDDHVHVVSNEILGLTNLLKDKKIKSKVIQFEVQFPTEEVAAHLSIDQKTPVYYVVRLRIVEGEPYVLEKTYMPTHLIPGINDDVLHDSIYNHITNVLQLKIAGTHRKIRACKSDHIDQQHLGCKQDDPILEVEHVGFLDTGIPFEYSFSRHRHDKFVVTSVNIRR
What is the function of this protein?
Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan.
What are the official names of this protein?
HTH-type transcriptional regulator GmuR, Glucomannan utilization operon repressor, Glucomannan utilization protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDNC_BACSU
Sequence: MKWGLVVLAAVFEVVWVIGLKHADSALTWSGTAIGIIFSFYLLMKATHSLPVGTVYAVFTGLGTAGTVLSEIVLFHEPVGWPKLLLIGVLLIGVIGLKLVTQDETEEKGGEA
What is the function of this protein?
Probably involved in guanidinium transport (PubMed:27989440).  In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials (PubMed:10735877).
What are the official names of this protein?
Probable guanidinium efflux system subunit GdnC.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. YkkC/YkkD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRC_PSYA2
Sequence: MVNVSVLSPVDDKKARLKHLIQRLPNLPGVYKMLGKNGDILYVGKAKSLKSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALLLEQNLIKEYRPPYNVLLRDDKSYLYVFISADQPYPRLAYGRGKVNHQKGCFFGPFPSAHAAKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSAEEYSEDVNNTIRFLKGDSSDIHSALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIASQVGMTCVNVLTVRGGRVLGGKNYFPDVDSSQPLADNLSAFITSFYFQVTDDLPAEIMLSHELPDQVAVSEALASHFGSKVVIKTNVREHRAEWLDLAKLNTNNALKTKLGDYLELHARFGALKDVLADITDRTIDRIECFDISHTMGEATIGGCVVFDQSGSRRRDYRQYAIHDIVGGDDYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGMLGDTLLIGVAKGEGRKAGLEVLHFIDHEPLDLPMDSKALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLGEKRRRDLLNHFGGLQQLLGASQQELAGVQGIGPILAKTVYKVLHE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_PHOLL
Sequence: MTTINHTLGFPRIGLKRELKKAQENYWAGKISQQELLETGRELRARHWEQQKQAGVDLVPVGDFAWYDHVLTTSLLLGNVPPRHQNPDGTIDLDTLFRIARGRAPTGEPAAAAEMTKWFNTNYHYIVPEFQQGQEFKLSWTQLLEEVDEALSLGHQVKPVLLGPITYLWLGKVKGQVFDRLSLLQDILPVYQQVLAELAKRGIEWVQIDEPALVLELPAEWLTAYPIAYQALQGQVKLLLTTYFDSIGHNLETIKSLPVQGLHVDLVAGQDDIAQLHESLPKEWVLSLGVINGRNVWRADLTAKHQLIKPLVGSRTLWIGSSCSLLHSPIDLSDETALDAEVKSWFAFALQKCEELALLTAALNQPDGSKQAELDAYSAPIRARRESKRVNNQAVTERLAAINPQDSERNQPYLQRAEIQRQRYNLPLWPTTTIGSFPQTTEIRGLRLDFKKGRVDGTSYRTNICEHIKQAINEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDVSRPEAITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVDDLQEAGIGIIQIDEPALREGLPLRREEWQSYLDWAVEAFKLNAAIAKDDTQIHTHMCYCEFNDIMPSIAALDADVITIETSRSDMELLDSFENFSYPNEIGPGVYDIHSPNVPSVEWIEALLRKAADRIPVERLWVNPDCGLKTRGWTETRQSLANMVQAAKRLRESVK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: 3HAO_DANRE
Sequence: MTNQSLHVNIDKWIAENETSFLPPVCNKLMFFYQLNIMYVGGPNVRKDYHIEEGEELFYQVRGDMVLKVIENGKHKDVHIREGEMFLLPARIPHSPQRQANTVGLVIERRRLSKETDGLRYFVANSTEVLFERWFYCENLGTQLVPIIKEFMDSKENETGKPDPANPIKPAPYPLNTMNVMTPFSFREWVEKQKPVLASGCPVDMFGEQFETETLLFGSGTSANKRRTDGWIWQLEGLSNVFMNGKEYSLTAGDCLLIFGETEYKWQRSQDCVALYVAQDPDRKRPY
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: LIPB_YEAST
Sequence: MSRCIRQSVCTNFNVCRRQCFSTYASALKEMTHPIKPSAQTLRHLQFTQRIPFQKGLEIQETLVRANLDIKDIQSKIERKLIQLDEEYKGTATINDNEKRILDKVMAMKPNPIILTFEFEPTYTGGKRIKKTMTPDQIAAYESFIPETQKDNPRPKFVQVERGGQVTFHGPGQIVIYIILDLKTFQSFPAKCLVSCIEQATIRTLKNTKMCDDTDKPLNLDAMTTKDTGVWVENGKKKVASVGIHVRRSITSHGVAINVNTDLSYMNSFEMCGLKNTLTTSIMEQRPDAVVNVQSVAISFVKEMTKLLGIKTLERMQIDDVNILKKNP
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
What are the official names of this protein?
Octanoyltransferase, mitochondrial, Lipoate biosynthesis protein, Lipoate-protein ligase, Lipoyl ligase, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NADE_ACIAD
Sequence: MKSFKIALAQFSPHIGNIDSNAQRMVEQANEAKKQNADLIIFPELSVIGYPAEDLLLRPNLNKRMQKAFQQLKEVKDIVMVFGFVHQTEEGHRYNSAAVMKDGVVLGVYNKHNLPNYSVFDEKRYFSPGHQHLVFEYLGHKFGVLICEDIWSINTVKQLSKLNVETVLVLNASPYEVGKPQHRVQTLTELSKQLNVHLVYLNQVGGQDDLIFDGSSFIINHDGEVAFQAPSFKEELYYSEFDIEQKRYKKIDPAPALDTIAEIYQSLVMATRDYVQRSGFSGVILGLSGGIDSALTLAIAADAIGADKVQAVMMPYTYTSQISVEDATEQARRMGVTFGIAEIHPIVNSFMQTLYPFFGNAPADATEENLQARARGTLLMGLSNKFGNLVLSTGNKSELAVGYCTLYGDMVGGFAVLKDVYKTIVFELAKYRNTLSETPVIPERVITRPPSAELRPDQKDQDSLPAYDILDAILYAYIEEDQSQSDIIAKGFDKEVVEKVIRLVDRNEYKRRQGAIGPRISSRAFSRERRYPIVNGWRPDD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses L-glutamine as a nitrogen source (PubMed:20926389).  In vitro, can also use ammonia as donor with comparable specific activity, but cannot use nicotinate mononucleotide (NaMN) as substrate (PubMed:20926389).
What are the official names of this protein?
Glutamine-dependent NAD(+) synthetase, NAD synthetase, NAD(+) synthase [glutamine-hydrolyzing].
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD synthetase family.
Protein: GMHA_VIBCH
Sequence: MYQDLIRSELTEAADVLQKFLSDDHNIAQIEAAAKLIADSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPGIAISDPSHLSCVSNDFGYDYVFSRYVEAVGAKGDVLFGLSTSGNSGNILKAIEAAKAKGMKTIALTGKDGGKMAGLADVEIRVPHFGYADRIQEVHIKIIHIIIQLIEKEMA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJC_BRUSU
Sequence: MFVTPAFAQASGSVVGPDMLMSILPFILIFVIMYFLIIRPQRTQMKKRQEMLNSVRRGDTVVTGGGIVGKVLKVVDDNELELEIADGVRIRVVRATLMDVRVKGEPVADNKNK
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC, Immunogenic membrane protein YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.