PharMolix/UniProtQA huggingface dataset:
Protein: RNPH_SHISS
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ATPB_EUGGR
Sequence: MKSSLRLNTGIILQIIGPVMDISFPSGKMPNIYNSLLIEGKTESGDRLKVVCEVQQLLGDNVVRAIAMSATDGLQRGIKVIDTGAPLSVPVGVTTLGRIFNVLGESVDKMGLIDYSITLPIHRAAPSFVELDTQLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYQEMKESGVINDRNFKESKVALIYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGGLQERITSTKVGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRNLASKGIYPAVDPLDSTSTMLQPWIVGEEHYNTAQSVKKTLQRYKELQDIIAILGLDELSEEDRLVVSRARKVERFLSQPFFVAEVFTGSPGKYVTLAETIEGFKAILSGDLDEVPEQAFYLVGNIEEVISKAIELQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RR4_ORYNI
Sequence: MSRYRGPRFKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKSSTGQVLLQLLEMRLDNILFRLGMASTIPEARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNSIASSDPGKLPKHLTIDTLQYKGLVKKILDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCSK4_MOUSE
Sequence: MRPSQTELWLGLTLTLALLAVRWASAQAPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKDPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCAIRVVHTPTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTLYYYTLLLYGTAEDMTARPQAPQVTSRARACVQRDTEGLCQESHSPLSILAGLCLISSQQWWWLYSHPQQPVTEGQASCHPPVTPAAAA
What is the function of this protein?
Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.  In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida (PubMed:9192653, PubMed:16371590, PubMed:19342015, PubMed:21302280).  Also plays a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2 (By similarity).  May also participate in folliculogenesis in the ovaries (PubMed:11164898).
What are the official names of this protein?
Proprotein convertase subtilisin/kexin type 4, KEX2-like endoprotease 3, Neuroendocrine convertase 3, NEC 3, Prohormone convertase 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane.
Protein: GCKR_MOUSE
Sequence: MPSTKRYQHVIETPEPGEWELSGYEAAVPITEKSNPLTRNLDKADAEKIVQLLGQCDAEIFQEEGQIMPTYQRLYSESVLTTMLQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASRERTEDSALHGIEELKKVAAGKKRVVVIGISVGLSAPFVAGQMDYCMDNTAVFLPVLVGFNPVSMARNDPIEDWRSTFRQVAERMQKMQEKQEAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGVVSSQRCLLEILRTFERAHQVTYSQSSKIATLTKQVGISLEKKGHVHLVGWQTLGIIAIMDGVECIHTFGADFRDIRGFLIGDHNDMFNQKDELSNQGPQFTFSQDDFLTSVLPSLTEIDTVVFIFTLDDNLAEVQALAERVREKSWNIQALVHSTVGQSLPAPLKKLFPSLISITWPLLFFDYEGSYVQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRIANSKLFWRALAMLQRFSGQSKARCIESLLQVIHFPQPLSNDVRAAPISCHVQVAHEKEKVIPTALLSLLLRCSITEAKERLAAASSVCEVVRSALSGPGQKRSIQAFGDPVVP
What is the function of this protein?
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme (PubMed:10713097).  Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10713097).  The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity).
What are the official names of this protein?
Glucokinase regulatory protein, GKRP, Glucokinase regulator.
What is the protein family that this protein belongs to?
Belongs to the GCKR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Note=Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus.
Protein: ALLR_SALTI
Sequence: MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPASRLTEDRFISQGELVRDTAKDISTALGLKPPVA
What is the function of this protein?
Negative regulator of allantoin and glyoxylate utilization operons.  Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
What are the official names of this protein?
HTH-type transcriptional repressor AllR, Negative regulator of allantoin and glyoxylate utilization operons.
Protein: MCES_CAEBR
Sequence: MSAAEVADHYNNVRQAGIQDRKESRIFFMRNMNNWIKSQLINDAMKLVNENGVKSPVVLDIACGKGGDLRKWDITGAKHVVMADVADVSIQQAEERYKTMHKYPHDIFGAQFIVADCTKENLDDKIEIKEPFDLVSCQFAMHYSFVDEDSARTFLKNAVGKLKLGGVFIGTLPDADRIVWAVRNGTEGKFANDVCKITYEKVDELSEGNVPLFGAKFHFSLDEQVNCPEFLAYFSLVKHLLEEHDMELLFVHNFAEAITNWLVPGRRLLESMKGLETFPNRNLSGKTDEEYLEAKAKIDSLGDNVPKFVGTLSKSEWEAICMYLVFGFRKKKTTEKNLESEAPEIKKVTPVPLNEDTDKTAEKNEERIEEKEENPSHC
What is the function of this protein?
mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.  Binds RNA containing 5'-terminal GpppC (By similarity).
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYOE_YERE8
Sequence: MMIKQYLQVTKPGIIFGNLISVVGGFLLASKGVIDYPLFLATLFGVSLVVASGCVFNNYIDRDIDRIMERTKNRVLVKGLIDPKVSLIYASILGIAGMLLLYVGANPLAMWLAVIGFVIYVGVYSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDMGALILLLIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVTKNHITLYILAFMVATLMLTLSGYAGYKYLVVAAAVSVWWLGMALRGYKATNDSVWARKLFVFSIIAITSLSVMMSVDFNVPSSAGLLTYVG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL9_STRP2
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAVGELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAEELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GAL1_SHIFL
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLNAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_SALNS
Sequence: MSEPTSSRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGISRESTEKTMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_SYNS3
Sequence: MSHPAHPRRFSALPQAFFCRPAEVVGPELIGCFLVKRQNDGSLLWGVIVETEAYSQDDPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRSDWANGVLLRAVAMPGEPERVAAGPGLLARRFGLNRTHDSQAVCGENEFWLASRPSVLNVPELVTTTRIGISQAQDLPWRWYLQDSRSVSRRARGDRMPALSQAFIPTLEWKR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: OV71_ONCVO
Sequence: KLIDELEEYKKRYDEALKAHQADREVIDDLLVKLSNLEAEINLLRRRVSNLEEEVSRIKKDNLYFVNELNKARANLDQETLNRIDFQNQVQTLLEEIDFMRRVHDQEISELQAMAARDTTSENREYFKNELSSAIRDIRAEYDQICNMNRTDMESWYKLKVQEIQTQSTRQNLEQGYAKEEVKRLRVQLSDLRGKLADLEGRNSLLEKQMQELNYQLEDDQRSYEAALNDRDAQIRKMREECQALMMELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLRQLVEQVVKTHGLSEIGETESIRVLKGETASRTSFQRSAKGNVSIQDASSDGKFILLENTHRSKEEPIGEWRLKRKIDGKREIVYTFPRDFILKPGKTVKIWARGQGVYSPPDQLVFDAEDSFGVGSNVQTILFNKEGEERASHIQRSSHTIS
What are the official names of this protein?
Muscle cell intermediate filament protein OV71.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: FBPC_VIBCH
Sequence: MEKQNFVVLKNICKRFGSNTVIGNLDLEIKKGSLVTLLGPSGCGKTTVLRLVAGLEKPTSGQIFIDGEDVTERSIQQRDICMVFQSYALFPHMSLYENVAYGLKMLKLPSEEVRQRVDEALKIVDLEGMGERYVDQISGGQQQRVALARALVLKPKVLLFDEPLSNLDANLRRSMRETIRELQQRFDITSLYVTHDQAEAFAVSDTVIVMKQGDIMQIGTPQELYKAPKSMFMANFMGEANMFQGHFDGQQIHINGYAIDADLEVTRDKPNGEYQIGVRPEAITLHTQGSESQACQILKSAYMGSMYEVTVKWHDQELLLQLNSAQFNHTLTQHAYVVFNPRGLFLLPYAE
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAZL_CALJA
Sequence: MSAANPETPNSTISREANTQSSSAATSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRGFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWSNPNTETYMHPPTTMNPVTQYVQAYPPYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSSVNYYCNEIDPGAEVVPNECSVCEATPPSGNGPQKKSVDRSIQTVVSCLFNPENSRLRNSVVTQDDYFRDKRVHHFRRSRAVLKSV
What is the function of this protein?
RNA-binding protein, which is essential for gametogenesis in both males and females.  Plays a central role during spermatogenesis.  Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).
What are the official names of this protein?
Deleted in azoospermia-like, DAZ-like autosomal, Deleted in azoospermia-like 1.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.
Protein: NTPP_MYCTA
Sequence: MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAR3_BOVIN
Sequence: MRAAIFAAIGALLLSPASCQSGMEYDADNLAKPTLSIKTFRGAPQNSFEEFPLSAIEGWTGTTKTVKIKCPEELDSNLHVNNATMGYLSSPLSTKLIPAIYILVFAVGMPANAVTLWMLFRTRTIRMTIFYTNLAIADFLFCVTLPFRIAYHLNGNNWVFGEVMCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKRTYALLTCGLVWTTVFLYMLPFFILKQEYYLVQQDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFLVIIYCYTAIIWTLNAKDRRWLWYIKASLLTFVIFTICFAPSNIILIIHHANYYYSNTDALYFVYLIALCLGSLNSCLDPFLYFLMSKITDHSTAYLTMVKLS
What is the function of this protein?
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
What are the official names of this protein?
Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUON_SALPA
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLANANHLATLFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGPGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBAY_ECOLI
Sequence: MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPAIQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFVLSFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPVQASGGATTTVPSTSPTQVNPSSAVPAPTQY
What are the official names of this protein?
Uncharacterized lipoprotein YbaY.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HEM3_CANGA
Sequence: MTRESINIGGRRSKLAVVQSNHVRDLVQAKFPQYDCTVFTLQTLGDQIQFKPLYSFGGKALWTKELEDYLYCEDQEKRLDLIVHSLKDMPTLLPDGFELGCVTKRVDPTDCIVMPRGSPHRCLADLPEGAVVGTSSVRRSAQLKRKFPHLKYQSVRGNIHTRLEKLDDPEGPFQCLVLASAGLVRMGLEDRITQRLHSDIMYHAVGQGALGIEIRQGDKKILQILDEIADLESTVCCLAERSLMRTLEGGCSVPIGVESSYDHKTKKLLLKGIVVNVEGTMAIEDQQEVVVNDIREDSIKCGVLLAHKMIKDGAKKILDEINLERVIQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: LSPA_CHLTB
Sequence: MPTRSLPTFLTLLLLASIDWVSKLVVLLKSCQLSPHSSAFLYSYVWGHFSFLIIPSFNEGAAFGLFAQYKIPLLIFRVCVILGLALFLRIKYKSLHRRTRIALTLILAGALGNVGDILLHGKVVDFLFLSYYSWRFPSFNLADAFISIGTLLLIGHLYFNKESKKCF
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MENE_STAAT
Sequence: MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMKSIDVQLIFCTLPLELRGFQIVSLDDIEFAGRDITTNSLLDNTMGIQYETSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQKILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNVYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: Y481_MYCTU
Sequence: MPRSFDMSADYEGSVEEVHRAFYEADYWKARLAETPVDVATLESIRVGGDSGDDGTIEVVTLQMVRSHNLPGLVTQLHRGDLSVRREETWGPVKEGIATASIAGSIVDAPVNLWGTAVLSPIPESGGSRMTLQVTIQVRIPFIGGKLERLIGTQLSQLVTIEQRFTTLWITNNV
What are the official names of this protein?
Uncharacterized protein Rv0481c.
Protein: RL32_BACC4
Sequence: MAVPFRRTSKTVKRKRRTHFKLSVPGMVECPSCGEAKLAHRVCKACGTYKGKEVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ISPDF_WOLSU
Sequence: MSQVSLVVMGAGESSRFRQGLSIKKQWLRLGETPLWKHVALHLSKQACFDQVIITASPKEVKYMQKQVDFEVIEGGGTRQESLQNALASVKTPWVLVSDVARFDVPSEVISRVIGRLGEAECVAPAIGVSDTVSYQGEYLSRSEVKLIQTPQLSHVESLLLAFRQGDFTDESSAIAKSGGRVLLVEGSERLKKLTHPHELTLLQGFEPPFGGCYGGSGFDVHAFMEGEGLRLAGVNIPAPVTFKAHSDGDVAIHALIDALLGAAGAGDIGEWFPDSDLAYKGVDSTLLLQEVIKFIRGIGFELINADLTIMAQAPKLSPYKEAMERRLGEVMEVSRQRISVKATTTESLGFVGRKEGVAVSAQVVLKLLDWTKHACFNR
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: SURE_WOLSU
Sequence: MLKRILITNDDGFDSPGLLALKEALCDVAHLTVVAPANEKSACGHGLTLTSPLRFIKLDDDVYKLRDGTPTDCIYLALNALYEEHSKPDLIISGINLGSNMGEDITYSGTASGAMEGVIHGIPSVAFSQLLHDKNTFGFDFALAKKVVRELTLKILSGGFPLGDRKFLNVNIPYVGIEEFKGYKVTEMGYRLYGNDAHLHRNPRGEEHYWLGLHPLAWNERNNARESDFKVATEGYVSITPIKLDLTSYEDIKELEAWI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5EAS2_NICAT
Sequence: MASAAVANYEEEIVRPVADFSPSLWGDQFLSFSIDNQIAEKYAQEIEALKEQTRSMLLATARKLADTLNLIDTIERLGIAYHFEKEIDEILDQIYNQNSTFDDLCTSALQFRLLRQHGFNISPQIFSKFQDENGKFKESLASDVLGLLNLYEASHVRTHTDNILEDALAFSTVHLESAAPYMNSPLREQVTHALEQCLHKGVPRVETRFFISSIYEKEESKNDMLLRFAKLDFNLLQMLHKQELAEVSRWWKDLNFVTTLPYARDRVVECYFWALGVYFEPQYSQARVMLVKTISMISIVDDTFDAYGTVKELEAYTDAIQRWDINEIDRLPDYMKISYKAILDLYKDYEKELSSAGRSHIVCHAIERMKEVVRNYNVESTWFIEGYKPPVSEYLSNALATTTYYYLATTSYLGMKSVAEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGVSTKEAMDKFQKMAETAWKDLNEGLLRPTPISAEFLTPILNLARIVEVTYIHNLDGYTHPEKVLKPHIIDLLVESIQI
What is the function of this protein?
Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol.  Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
What are the official names of this protein?
5-epi-aristolochene synthase 2, NaEAS37.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIF5_ORYSI
Sequence: MAEERRRDDGGDVEVELSLRLRTGDDSTSADPAPATVAAEARRNLTIFYNGRMCAVNVTELQARTIISMASQGNFGKQQQQQIQGRDDHHYHQGESSSGGGVSTAAARHCDVAGSSSSHSGSGSGSATPPRPALVSPRAGLQAAAAAAPTMNQPPAASGLSMKRSLQRFLEKRKTRAAAPLYARR
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 5.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CA109_MOUSE
Sequence: MAHDQPLLVVQEALRKCFPVVEEQQNLWQSTLQDCSPLLSSLSNLAEQLQAAQSLRFEDVPALRPFPDLQERLRRKQLEAGDVVLDKLAERLATLLKVRNTINSHVEQVFQAYEQHAAVLDIDTVLRPSVVSPSVADMLEWLQDIDRHYGSSYLKRKYLLSSIHWGDLASIQALPKAWDQISENECQTLVSDVLVSVSFFLEEPGGCAASGDLEHHS
What is the function of this protein?
Involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles.  Acts together with SPATA5, SPATA5L1 and CINP.
What are the official names of this protein?
Ribosome biogenesis protein C1orf109 homolog.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.