PharMolix/UniProtQA huggingface dataset:
Protein: PSBA2_SYNR3
Sequence: MSTAVRSGRVSSWESFCQWVTNTDNRIYVGWFGVLMIPCLLAATICYIIAFIAAPPVDIDGIREPVAGSFLYGNNIISGAVIPSSNAIGLHFYPIWEAATLDEWLYNGGPYQLVVFHFLIGISAYMGRQWELSYRLGMRPWICVAYAAPLSAAMVVFLIYPFGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTESESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTSMGIATMAFNLNGFNFNQSILDAQGKVVPTWADVLNRANLGMEVMHERNAHNFPLDLATTESAPVALQAPAVG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 2, PSII D1 protein 2, Photosystem II Q(B) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: LPXH_PSEA8
Sequence: MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CREB_ASPTN
Sequence: MGSLFRSFRRDAGATAPSVGATPAKKEPPPPPMTPLEKMLQDMGAIREDGSDKFFGMENYGNTCYCNSILQCLYYSVPFREAVINYPTRTPIESLTAALAETLRYPNPNAHLEAEAQAEKQKAANAQRPGAPPNQPQKPEDKDSPEYKKKMALQTFPLLETKNNAPSYGMSESLFTSLKDLFESVVGSQSRIGIVRPQHFLDVLRREHEMFRTAMHQDAHEFLNLLLNEVVANVEAEALKQPSLERSLPPAESSESVEHSGSSGSKTPNTTRWVHELFEGTLTSETQCLTCEKVSQRDEVFLDLSVDLEQHSSVTSCLRKFSAEEMLCERNKFHCDNCGGLQEAEKRMKIKRLPRILALHLKRFKYTEDLQRLQKLFHRVVYPYHLRLFNTTDDAEDPDRLYELYAVVVHIGGGPYHGHYVAIIKTQDRGWLLFDDEMVEPVDKNYVRNFFGDKPGLACAYVLFYQETTLEAVLREQEQENMDPALATTETNDSLKQNGFAQSPALGLVHSASQIPSHDEPHRLNSLKRAPTAPSLPTHYEHTDTNSAPSIPKPAMAPPVPPIPETHSMPLSPKKSDLQSRKERAKEEKERKAAEKERERQRRKEQEATRKEQEARARENQRREDAELKAALEASRASKADEDRRNQEGQKDRDPGRSGHGLSRLKRGSKSFSHRLSKDKDTRVPSSSNPGVPDPNSPPLNNTVVTSEHQEQEQQPPSDQQPGASRLSKKHNLNDEERDANKDPKQDKPGHGKWRSFSLRKKSLGILS
What is the function of this protein?
Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Deubiquitinates the creA catabolic repressor and the quinate permease qutD.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase creB, Carbon catabolite repression protein B, Deubiquitinating enzyme creB, Ubiquitin thioesterase creB, Ubiquitin-hydrolyzing enzyme creB, Ubiquitin-specific-processing protease creB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: COAX_FRASN
Sequence: MLLTIDVGNTNTVLGVFDGDQLANSWRVRTDPRATADELGWLYRGLLGDHPIGGVSVCSTVPAALREIRRMVSRTFPAMPTVVVEPGTRTGVPILIDNPKEAGADRIMNTLAAHHLYGGPAIVVDFGTATNIDVVSARGEFLGGAFAPGIEVALDALASRAAQLRNVELTTPRSVIGKSTVEALQSGMIYGVVGQVDALVRRIRAELGTPATTIATGGLAPLVIKESETLDNHEPHLTLIGLRLVFEKNTEPR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S3_BOVIN
Sequence: MESQSRRRRPLRRPETLVQGEAAESDSDLSASSSEEEELYLGPSGPTRGRPTGLRVAGEAAETDSDPEPEPKAAPRDLPPLVVQRETAGEAWAEEEAPAPAPARSLLQLRLAESQARLDHDVAAAVSGVYRRAGRDVAALAGRLAAAQAAGLAAAHSVRLARGDLCALAERLDIVASCRLLPDIRGVPGTEPEQDPGPRA
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Plays a role in intracellular vesicle trafficking (By similarity).
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 3, BLOC-1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_SORC5
Sequence: MLLGRPLSLADLEEIARRGRPVAICAEARERAAASRRAIDAIAAAGDAAPAVYGINTGFGALAETRIADHDIRALQRNLVRSHACGVGPELGEAEVRAMIVLRAQVIALGHSGVRTEVLDLLAALLERRVSPRIPAQGSVGASGDLAPLAHLALTLIGEGEARFEGQLLPSAVALAKAGLAPIELAAKEGLALINGTQYMTALGALALRDAAALCTVADIAGAVSLEALMGSKRPFDERLMRVRPHPGQAGTAGNLRALLGGSEIMQSHADCPRVQDAYSLRCMPQVHGATRDAVAWAAEVLTREVNSVTDNPTVFLGDGADGGAELISGGNFHGQPVALALDLAAMAAAELANISERRVEQLVNPALSTGLTPFLAPHSGLHSGFMIAQVASASLVSENKVLCHPASVDSIPSSAGREDHVSMGSISARKLAQVIENVRSSLAIELITAAQGVDQRLPLRPSAGVAAAHAAIRRVVPGLTEDRPLYRDIAAAAELIQSGALIAAVEEAVGPLN
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPI_GEOSW
Sequence: MDLNLRHAVIQNIANNTKEQLEDTIVDAIQRGEEKYLPGLGVLFEEIWKHSSEQQKEEMLTTLEQAVKQHA
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: TOXR_VIBCH
Sequence: MFGLGHNSKEISMSHIGTKFILAEKFTFDPLSNTLIDKEDSEEIIRLGSNESRILWLLAQRPNEVISRNDLHDFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPQYVKTVPKRGYQLIARVETVEEEMARESEAAHDISQPESVNEYAESSSVPSSATVVNTPQPANVVTNKSAPNLGNRLLILIAVLLPLAVLLLTNPSQTSFKPLTVVDGVAVNMPNNHPDLSNWLPSIELCVKKYNEKHTGGLKPIEVIATGGQNNQLTLNYIHSPEVSGENITLRIVANPNDAIKVCE
What is the function of this protein?
This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V. cholerae.  It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region.  ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity.  It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.
What are the official names of this protein?
Cholera toxin transcriptional activator.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL34_ACIB3
Sequence: MKRTFQPSELKRKRVHGFRARMATKAGRQVLARRRAKGRHSLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DXS_THERP
Sequence: MYLERIDSPQDLKRLSVPELEKLAEEIREAIIEVVLGKTGGHFAPNLGTVELTLALHYVFDSPRDKIVWDVGHQAYPHKLVTGRRDRFHTIRQEGGLSGFLQREESPHDHFGAGHASTSISAALGMAVAAKLRGDRYHTIAVIGDGALTGGMAYEALNHAGALQVPLIVVLNDNEMSIAPNVGALARYLTRVRTDTRYRQAKVEIERLLRRLPQGERLVELSHRFLDGLKEVVYRTMIWEELGFTYIGPIDGHNLRELIETFQLVKTFDSPVFVHVLTVKGKGYQPAEDDPFKHHSAAVKVPGAPPTPPRYQDVFGQTLVELAAKNDRIVAITAAMPDGTGLLPFAAAYPDRFFDVGIAEQHAVTFAAGLATQGLRPVCAIYSTFLQRAYDQVIHDVCIQKLPVVFAMDRAGLVGEDGRTHHGVFDVAYLRCLPNMVLMAPKDEDELRHMLATALAYEEGPIALRYPRGSGVGVPMLGEPRVLPIGRAELLREGSDVAIVALGATVLPAERAADILAERGIRATVINARFVKPLDRSLILDAARECGCLVTVEEAQLAGGFGSAVLETLADAGLLIPVLRLGLADRFFDHASQASLRRQAGIDAESIASRTLAFLATHGRIETGAISDR
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: F182B_HUMAN
Sequence: MQEMVRELWMWNVEEEEHEVGICTWGGQHCGCPAKSLPGPHPGGVSAPQSASQLMVKLLVWQKSVHKLRKVSATSSIAVYPCPGQSSGGAESPAPGPGLAGWSHLCGAALAEVQAAPVSQAAVSDASLGPEWSQEGCRPGLTSGQHGGRDGR
What are the official names of this protein?
Protein FAM182B.
Protein: RL17_CUTAK
Sequence: MPKPTKGPRLGGSPAHERIILRNLASQLFEHGHVVTTVTKAKRVRPLAEKLINRAKTDTVANRRFVNRTITDRGIVHILFTEIGPRMEGRDGGYTRVTRIGNRKGDNAPMAVIEVISDKVAPKAPASAADAKAQINTATEAKEAEPEAPAEDAAAQAPVADEQKAAEVDEKAEEKPEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: H4_LOLTE
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GPDA_KLEP7
Sequence: MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFPDTLHLESDLATALAASRDILVVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATDPQFAEDLQRLLHCGKSFRVYINPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRLGVEMPITEEIYQVLYCGKIAREAALTLLGRARKDERSSN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_NOTPE
Sequence: VTVDCSGYPKPACTLEYFPLCGSDNQTYANKCTFCNAVVEKNVTLNHLGEC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: LIP1_KLULA
Sequence: MATQQNKNRVYILLQYVLAALVLIAAVEYFKYKTRISYEWFHCTVQSEELFDHPEGSPLKLWAIGGPSCDKRGELKTIMKRITMDFDPNVEPVKFCIVEDTKVKSIHYPIEDGNKGDPGYISFVGYERDSDVVEQACASYAATVFNL
What is the function of this protein?
Component of the ceramide synthase complex required for synthesis of ceramides.
What are the official names of this protein?
Ceramide synthase subunit LIP1.
What is the protein family that this protein belongs to?
Belongs to the LIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: HEMA_INBHM
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALARPMCVGTTPSAKASILHEVRPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTQNVINAERAPGGPYRLGTSGSCPNVTSRDGFFATMAWAVPRDNKTATNPLTVEVPYICTKGEDQITVWGFHSDSKTQMKNLYGDSNPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RS21_LISMF
Sequence: MSKTVVRKNESLEDALRRFKRTVSKSGTLQESRKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CISY_CAEBR
Sequence: MPITGTVLRRFITKGVIPMCQVAPLSTSAEGSTNLKEVLSKKIPAHNAKVKSFRAEHGNTVVQSVNIDMIYGGMRSMKGMVTETSVLDPEEGIRFRGYSIPECQKLLPKAKGGEEPLPEAIWWLLCTGDVPSEAQTAAITKEWNARADLPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEYAYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGYDDPLFAELMRLYLVIHSDHEGGNVSAHTSHLVGSALSDPYLAFSAAMAGLAGPLHGLANQEVLVFLNKIVGEIGFNYTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLFKLVSTLYKITPGILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRALGCLSQLIWARGMGLPLERPKSHSTEGLIKLAMAAKK
What are the official names of this protein?
Probable citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: EF1B_NATPD
Sequence: MGKVAAKMKVMPQSPEVDLDELQDRLENSLPEGAKISRVDREDVAFGLIALFPTVIIPDEAGGTDTVEDAFSGVDGVESVDVDEVGRI
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: LEUC_PSEPK
Sequence: MAGKTLYDKLWEAHEVKRRDDGSSLIYIDRHIIHEVTSPQAFEGLRLANRKPWRIDANIATPDHNVPTTPERKGGIEAIVDQVSRLQVQTLDENCDEYGIVEFKMNDERQGIVHVISPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVRVEGQLPAGVTAKDIVLAVIGKIGTAGGNGHAMEFAGSAIRELSMEGRMTICNMSIEAGARVGLVATDATTVAYVEGRPYAPKGEQWKQAVESWKDLVSDDDAVFDTVVELDASQIKPQVSWGTSPEMVLAVDQRVPDPAAETDLVKRGSIERALKYMGLTANQAITDIKLDRVFIGSCTNSRIEDLRAAAEIAKGRKVAASVKQAIVVPGSGLVKAQAEREGLDKIFLEAGFEWREPGCSMCLAMNPDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVAGHFIDVRELIQGSAA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CDMH_TALVE
Sequence: MAVLKQPQHHHGKHGGRSFYQLIAYLMLTSRLDNYGMLFTSFGGAGIYKSQDYTSTTSQASILRLAGLCTAHCVLLGAAGNTWNDWMDRDIDSKVARTKDRPLASGKISSGEAFTWMAFLYSTSVGMLKAMLGDRNVWPFMVPLTAIILVYPLGKRPIARKLRIYPQYLLGIAVGYPTMYGWAAVYGPCMPISEILHRCVPLWIFLFFWSFYANTSYSYQDVEDDRKMKVNSAYNLAGKRIRALLAILASIALSTIPFVLRPFSSAWLWLSWVGAWVPGIIQQLLSFDPSKPESGGVLHLSTVKLGLWTVFACTLELYLSNRAVI
What is the function of this protein?
6-hydroxymellein 5-farnesyltransferase; part of the gene cluster that mediates the biosynthesis of chrodrimanin B, a meroterpenoid that acts as a potent blocker of insect GABA-gated chloride channels (PubMed:30417647).  The first step of the pathway is the biosynthesis of 6-hydroxymellein by the polyketide synthase cdmE (PubMed:30417647).  The prenyltransferase cdmH acts as a 6-hydroxymellein 5-farnesyltransferase and produces the hydrophobic metabolite verruculide C (PubMed:30417647).  The FAD-dependent monooxygenase cdmI further converts verruculide C into verruculide B (PubMed:30417647).  The terpene cyclase cdmG then produced the pentacyclic molecule 3-hydroxypentacecilide A, the backbone structure of chrodrimanin B, via folding the farnesyl moiety of the substrate into the chair-boat conformation (PubMed:30417647).  The short-chain dehydrogenase/reductase cdmF functions as the 3-OH dehydrogenase that oxidizes the C-3 hydroxyl group of 3-hydroxypentacecilide A and produces chrodrimanin C, the dehydrogenated product of 3-hydroxypentacecilide A (PubMed:30417647).  The cytochrome P450 monooxygenase cdmJ then accepts both 3-hydroxypentacecilide A and chrodrimanin C and functions as a C-7-beta-hydroxylase to produce respectively chrodrimanin H and chrodrimanin F (PubMed:30417647).  The dioxygenase cdmA accepts chrodrimanin H to afford chrodrimanin E, which is further transformed to chrodrimanin A by the dioxygenase cdmD (PubMed:30417647).  CdmA can also accept chrodrimanin C as substrate to convert it into verruculide A, which is further converted into chrodrimanin T by cdmD (PubMed:30417647).  The last step of the biosynthesis is proposed to be performed by the acetyltransferase cdmC which acetylates chrodrimanin A to yield chrodrimanin B (Probable).  The pathway may also lead to the production of additional shunt products, including chrodrimanins T and U (PubMed:30417647).
What are the official names of this protein?
6-hydroxymellein 5-farnesyltransferase cdmH, Polyprenyl transferase cdmH, chrodrimanin B biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEOC_ECO24
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEP_MELGA
Sequence: VPCQIFQDDTKTLIKTIVTRINDISHTSVSAKQSVTGLDFIPGLHPILSLSKMDQTLAVYQQVLTSLPSQNVLQIANDLENLRDLLHLLAFSKSCSLPQTSGLHKPESLDGVLEALLYSTEVVALSRLQGSLQDILQQLDISPEC
What is the function of this protein?
Key player in the regulation of energy balance and body weight control.  Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
What are the official names of this protein?
Leptin, Obesity factor.
What is the protein family that this protein belongs to?
Belongs to the leptin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MINE_VARPS
Sequence: MSFFSFLLGEKKKTASVAKERLQIILAHERSSLSGKKRPDYLPDLQRELMAVISKYVKINADDIKVHLEKQDDLEVLDIKIELPDPAPSPAR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: KAD_PYRHO
Sequence: MNILIFGPPGSGKSTQARRITERYGLTYISSGDIIRAEISSRTPLGLEMEKYLSRGDLIPDTIVNTLIISKLRRVRENFIMDGYPRTPEQVIALENYLYDHGIKIDVAIDIFITKEESVRRISGRRICSKCGAVYHIEFNPPKIPGKCDICGGDLIQRPDDRPEIVEKRYDIYMRNMEPIIKFYQKQGIYVKIDGHGSINEVWERIRPLLDYIYNTRSRR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAMKA_DICDI
Sequence: MDTSAVSYLSSIVLNNNYKEWNNEKIIKWLSDTKKIQKVIVFKIYEITGRDLEFLSDKILFKMGVGIRDLLSFKSEFEILKNNYDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNSNSNSTNINNNCSNNNSNNNHINFNSNSNITNIKNNDSKIKNKKEENKVPIIDLNQYEYVESISLGVFSVVGKYKRKGQENEFIAIKKIDILSLNEEKIIKEINKLYSINHPNIIKIIGYCKDQKNYYIASKYYPKGSIKKNTKQSPYSEMNAKRISVKILSGIDYLHSLNPPIIHRDIKCDNILLDENDDPILIDFGLSYKTIDDSTNLKTLCKKPFWASPDVNNQEIQIFSEKTDIYSFGCTIFEMIVGWESYSKKENNQPNLQKLPDNLTISCRLALGDIIGLEQNFKPDSKDLQKLSWFNESLPPIFQSQELTKSTTNTTTTTTTTTTPPPPPSPSSSSPSMNENKKIVTSDCLINSFKESGCLIFLNGELMYDNPFDKDCYQYNIVIPFGTPHLREVIHKDKNKSKHLDKIELFIDDHLAKGLVIKLGNFKLDLSKEFKKTPTFIDSIIEYLLDLLQKDNDDDDDDDVPESIILNIAVGFYKYISNFITYQYVLNQPSHFC
What are the official names of this protein?
Probable serine/threonine-protein kinase samkA, SAM domain-containing protein kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NUOB1_CERSK
Sequence: MTGLNTAGSDRDYDTQSLNRELQDKGFLLTTTEDLINWARTGSLHWMTFGLACCAVEMMHTSMPRYDVERFGVAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIRRTGTITR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BTN1_ASHGO
Sequence: MDRRKLIFGKFWLFGLLNNVLYVVILAAAVDIVGPTLPKSLILLADILPSFLVKLVAPFFIDRVEYHYRIWSLIALSGFGMLLVASGRLGVCIVGIVLASISSGVGEITFLQLTHYFSHVALNGWSSGTGGAGLAGSFLYMLLTSILKIPVSRSLLLFSILPIGFLLYFTLQVERTAYEPLASGHFMEAEDNSGSVISLEAPRTTVDNARDCASRPRLAALRERIEVTMRRLKVLVVPYMIPLSTVYLFEYLINQGVSPTLMFPIHEGYGTSQLFHKYRDIYVAYGTLYQLGVFISRSSGSWVRIRGLYLLSVLQFLNLVILLIQSWYYVIHSVWVIMAIVLYEGLLGGASYVNSFLNISEDVPLAEREFSLGAVSISDSSGTLVAAFIGILLEPVLCSHQVKTGRPWCQLE
What is the function of this protein?
Involved in vacuolar transport and vacuole pH homeostasis.  Also required for cytokinesis (By similarity).
What are the official names of this protein?
Protein BTN1.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.