PharMolix/UniProtQA huggingface dataset:
Protein: PXPA_VIBCH
Sequence: MSKRTIQLNCDMGESFGVWTMGADEEVMPWIDMANIACGFHASDPHVMSRTIDLALEHEVMIGAHPSYPDLQGFGRRSLAMNEQEVSEIILYQVGALKALCESKNGQLSYVKPHGALYNDMMSDPSIFRAVVDAVSCFNLPLMVLASANNQDYLDIADRFDVPLLFEAFADRTYLANGKLTPRSQPNAVLSSEEAILNQVRQIARYGKVTSSDGFVIPIEADTLCVHGDNPNAVSLIARIRAALDE
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL20_THEM4
Sequence: MRVKNAVNAKKKRKKIMKAVKGYRGALSRRYRLAKQAYIKAKKHAYVGRKLKKRDYRKLWITRINIAARNEGLKYNELIHGLKISGININRKMLAELAVNDPESFKEYVNIAKQAIGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CARB_BIFLO
Sequence: MPKRTDIKSVMVIGSGPIVIGQAAEFDYSGTQACRVLREEGIRVILVNSNPATIMTDPEMADATYIEPIATPILEQIIAKERPDALLPTLGGQTALNAAMALGEAGVLKKYNVELIGASLEAIDRGEDRELFKKVVDEAGAESARSDIAHSIEEVDKIAEKFGYPLVVRPSFTMGGLGSGIAHNEEELHRIAGAGIHYSPTDEVLIEEGIEGWKEFELELMRDRNDNVVVVCPIENVDPVGVHTGDSITVAPCFTLTDREYQKLRDIGIAIIRGVGVDTGGCNIQFAVHPDTGRIIVIEMNPRVSRSSALASKATGFPIAKIATKLALGYTLDEIRNDITQSTPASFEPTIDYVVTKVPRFAFEKFPGADPTLTTSMKSVGEAMALAGNFQESLGKAMRSIDKRHMGFNWDGEKPSAEEVAELLEAIHTPTEHRYLQLMRAIWGGATLEQVFAATKIDPWFLKQIFLINETAMTVREAETLTPRLLKKAKLAGLSDVQVAHLRGLGDEGENTIRELRWTYGLRPVYKTVDTCAAEFDAATPYYYSCYADETELRPREREAVIILGSGPNRIGQGIEFDYTCVHAVQELGKDYDTIMVNCNPETVSTDYDMSDRLYFEPLTFEDVLEIYEAEKKMGPVKGVIVQLGGQTPLSLAARLKAAGVPILGTTPESIDLAENRELFGEVLKKAEMNAPRYGTALSLEEAKEAAHRIGYPVLVRPSYVLGGRGMEIVYDDKQLNKYVDRALAEAKADTVVSGRLPSPLLIDKFLQDAIEIDVDALFDGEELYIGGIMEHVEEAGVHSGDAACTLPPSTLSDDQIRRLREGTYAIAKGCHVQGLINVQYAFMANTLYVIEANPRASRTVPFASKATGVALAKAAARIMAGETIADQRANGLLLPKGDGGDIHPGQQVAVKESVLPFKRFRTPVGKTVDILLGPEMRSTGEVMGFDRDFPHAFAKSQLAAYDGGLPTHGNVFISVNDTDKRQLPLIAVRLEELGFKLWATEGTASVLRRYGIESNIVDKISTRVDTDPEAPVEVHHAAGSVGKNVVQLIEEGKIDMILNTPNSRGSRSDGYSIRAAAIAADLPQFTTITEFQAALLAIEAVKHNDYQIMSIQEHSKQLFELERREF
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: Y1986_DEIRA
Sequence: MSIAIVTDSTSDLTPEHLAALGVTGVPLYVLFEGQLYQDGVQLSARQLVEGVRAGKAIPSTSQPSPAEFAQAYAQALEHADEVLSLHISGQLSGTVGSARLAAQEFGGRVTVVDTHTVTLGLGLQVLRAAELVRAGQSVPQIVQTLERVYPQADLRFTVDTLDFLRLNGRIGGASALLGGLLNIKPLLVVRGGRVDAGGRVRGQKKALADLAEHVRRYVSQHGGARVAFLATVGGEEDRAAVRAQLSDLHFQDMGDHEIGAVVTVHAGPGAVGVALEPLSA
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein DR_1986.
Protein: SKPL_PSEAE
Sequence: MRKFTQFVLITAAIMAAPSAFAEMKIAVLNYQMALLESDAAKQYAVDAEKKFGPQLNKLKNLERDAKALQDKLVSNGSKMSQGDREKAELDFKQKARDFQFQSKELNESKAAADRDMLKKLKPKLDQAVEETIKKGGYDMVIERGAVVDVKPQYDITRQVIERMNQLR
What are the official names of this protein?
Skp-like protein.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
Protein: SYM_STAAC
Sequence: MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGHEVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRTSFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYYLMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHELDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQKDMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLNESIMVTGQPKPIFPRLDSEAEIAYIKESMQPPATKEEKEEIPSKPQIDIKDFDKVEIKAATIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLMGQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBAB_ECO55
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL16_EHRCR
Sequence: MFIPKKTKYKKDFKGRISGNAKGGYTLSFGSHGLKALEPSRLTSKQIESARRSISRTLKRVGKVWIRAFCHTSVSKKPMDVRMGKGKGSVEMWVCKVKPGKILFEIGGVPLNLAREALNKAQAKLPMKCKFVSDEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DEOB_ELUMP
Sequence: MKRVIILMMDSFGIGGAADAAKFGDEGANTLASVAKLNNGLKIPNLISLGLVKAAEASAGVKIETGPQPPAQVNIPSKYGFMREQSHGKDTLSGHWEMAGVPVLFDWGYFKPGYPSFPKELIEQICKEAGIDKILGNKAASGTEILEELGEEHIKTGKPICYTSADSVFQIAAHEKHFGLERLYTICEIAFKYLKPYKIARVIARPFEGERKGEFKRTKNRHDYAVKPPAPTVLDFLKENGGNVISIGKINDIYAKQGITKAVKASGLEELWNTTIEETKNASGNSIIFTNFVDFDMVWGHRRDFKGYAGGLEYFDSRLPELANILQEGDLVFITADHGCDPSYKGTDHTRENVPAIMFGKNVKNGFIGGRETYSDLGQTVAEYLGITKLNNGTSFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURO_META3
Sequence: MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAYNCIKIVGNTVIATNGTHTDIIADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNENTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEHQNIVVDGENPEEICKFVMDYEKFEKPVCCATATIDGDIELGTL
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: HLDE_SHESH
Sequence: MKVSLPAFEKAKVLVVGDVMLDRYWTGPTGRISPEAPVPVVKISQIEDRPGGAANVALNVATLGGQVSLAGIVGKDEAADALTTGIQALGVEPKWHCVEGKPTITKLRVMSRNQQLIRLDFEEAYPEDESKALLTLSESALDNVAVVVLSDYAKGAITQPQEFIQKAIAKGVKVLVDPKGSDFSRYRGASLITPNMGEFEEVVGSVSSEAELVEKAQALLSEFDIEAILVTRSEKGMTLITADAPELHIPTVAREVYDVTGAGDTVISALATSLAAGSDLPQACAIANTAAGIVVAKLGTSTVSRIELIRALSVNHGESGFGAVSEDQLAYALEQARLRGERVVMTNGCFDILHAGHVSYLKQARELGDRLIVAVNDDDSVKRLKGEGRPVNQSDRRMAVLAGLASVDWVVPFTEDTPQRIISRLLPDLLVKGGDYKIEDIAGGKEVIAAGGSVKVLGFEDGVSTTSIIENIMANQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: GLAH_ECOHS
Sequence: MNALTAVHNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: YJQA_BACSU
Sequence: MGFIDGLLGNASTLSTAAVQEELAHILLEGEKVEAAFKLVRDLIVFTDKRLILVDKQGITGKKTEFQSIPYKSISRFSVETAGRFDLDSELKIWISGAELPAVSKQFKKDESIYDIQKVLAAVCM
What are the official names of this protein?
Uncharacterized protein YjqA.
Protein: CAPSD_BPS13
Sequence: MSNVQTGAERMPHDLSHLGFLAGQIGRLITISTTPVIAGDSFEMDAVGALRLSPLRRGLAIDSTVDIFTFYVPHRHVYGERWIKFMKDGVNATPLPTVNTTSYIDHAAFLGTINPDTNKIPKHLFQGYLNIYNNYFKAPWMPDRTEANPNELNEDDARYGFRCCHLKNIWTAPLPPETELSRRMTTSTTSIDIMGLQAAYANLHTDQERDYFMQRYRDVISSFGGKTSYDADNRPLLVMRSNFWASGYDVDGTDQTSLGQFSGRVQQTYKHSVPRFFVPEHGTMFTLALVRFPPTATKEIQYLNAKGALTYTDIAGDPALYGNLPPREISMKDVFRSGDSSKKFKIAEGQWYRYAPSYVSPVYHLLEGFPFIQEPPSGDLQERVLIRHHDYDHCFQSVQLLQWNSQVKFNVTVYRNLPTTRDSIMTS
What is the function of this protein?
Assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins F.  Upon virus binding to host cell, one of the spikes dissociates from the capsid and the virus interacts with LPS through the exposed EF loops on the F proteins.  After the genome had been ejected, the channel formed by the F proteins at the unique fivefold axis remains open.
What are the official names of this protein?
Capsid protein F, F protein, GPF.
What is the protein family that this protein belongs to?
Belongs to the microviridae F protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DSBD_PSEF5
Sequence: MRRLFLLLFMLFTTLAHAGNNPFEVKPDFLPVGKAFVFTSERLPSGETQLFWQIADGYYLYQKRLKFDGVAPELQPTLPAGEDHSDEFFGQQTVYRQGLEVKLPAAASGKVKLGWQGCADAGLCYPPQTLEVDLGGAPAVAASNVATTSNGSAQDQLLANDLQHKSWGLGLLAFFGFGLLLAFAPCSLPMLPILAGMVVGSGASPRRGLALASSYVLCMALVYAGMGVIAALLGSNLQAWLQQPWVLGSFAALFVLLSLPMFGFFELQMPALLRDRLEGASRQRQGGSLIGCGILGALSALLVGPCMTAPLAGGLLYIAQTGNALFGGLALFALGLGIGLPLLLLVTLGNRFLPKPGPWMNLLKGVFGILFLGTAIYMLRPVLNPGLWMGLWGALALVVAYCAWQQRAIAGRLLHLFGAGALLFAAWGGMLLVGAAGGGDDLWRPLKVYRGGPVANSVTAHDAFTTVKSPAELQGALDSARAQGQWVLLDYYADWCVSCKIMEKTVFGQPQVLEALKDVRLLRLDVTLDNADGRELLSRYKVPGPPSMLWIGPDGSERRSQRITGEVDANAFLQRWTQTREAR
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAB_CYACA
Sequence: MATKFPKFSQSLSSDPTTRRIWYGIATSHDFEAHDNVTEENLYQKIFASHFGHLAIIFLWTSGNLFHVAWQGNFEAWIANPLKVKPVAHAIWDPHFGQAALKAFSRGGVNYPVDISYSGVYHWWYTIGMRTSSDLYAGALFLLVLAALCMFAGRLHLQPKFKPSISWFKNNESRLNHHLSGLFGLSSLAWCGHLIHVAIPASRGQHIGWNNFLTTPPHPAGLKPFFTGNWSDYSLNPDDPSHIFGTSSNSGKAILTFLGGFHPQTQSLWLTDIAHHHLAIAVIFIIAGHMYRTNFGIGHNIKDILEAHKPPSGKMGLGHKGLFNTISNSLHFQLGLALACLGVLSSLTAQHLYSIPPYAFISRDFVTQAALYTHHQYIAGFLMVGAFAHGAIFFVRDYDPKQNKDNVLYRMLEHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGNPEKQILIEPIFAQWIQATSGKTLYGFNVLLASSSSSATQAAQSLWLPNWLEAINNNNNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLGVFWMLNTIGWTTFYWHWKHITIWQGNASQFNESSTYLMGWFRDYLWLNSSPIINGYNPYGMNNLSVWAWMFLFAHLVWATGFMFLISWRGYWQELIESLVWAHERTPLANLITWKDKPVALSIVQARLVGLVHFSVGYVLTYAAFVIASTAGKFN
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MDTI_SALTY
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUX2_HUMAN
Sequence: MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGGGGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQRGSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSVAPLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRGRSVPPSPPERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIGDAGYFDHHWASDRGLLSRPYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAAGAEDEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTPEQYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSDQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLESSKENQQPEGRSSSSLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTGSDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF
What is the function of this protein?
Transcription factor involved in the control of neuronal proliferation and differentiation in the brain.  Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III.  Binds to DNA in a sequence-specific manner.
What are the official names of this protein?
Homeobox protein cut-like 2, Homeobox protein cux-2.
What is the protein family that this protein belongs to?
Belongs to the CUT homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LARP4_HUMAN
Sequence: MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSIYSHPIQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPPRSPK
What is the function of this protein?
RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120).  Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120).  Plays a role in the regulation of mRNA translation (PubMed:21098120).  Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744).
What are the official names of this protein?
La-related protein 4, La ribonucleoprotein domain family member 4.
What are the subcellular locations of this protein?
Cytoplasm, Stress granule. Cytoplasm, cytosol. Note=Localized throughout the cytosol. Partially localized in stress granules in response to arsenite treatment.
Protein: PUR5_GEOSM
Sequence: MKETKITYKDAGVDIDAGNTFVQMIKPLVKATSRPEVLADIGGFGGLFSLNMGKYKHPVLVSGTDGVGTKLKLAFLADRHDTIGIDLVAMCVNDIIVQGAEPLFFLDYLATAKLDPVKAASIIKGVSEGCVQAGCALIGGETAEMPGFYTGDEYDMAGFAVGVVEREKIIDGSSITVGNRLIGLASSGLHSNGYSLARKVILEHMGLGIDDELPGLGKTVAEELLTPTRIYVRSVMNLLRDFNISGLAHITGGGLLENIPRVLPNGCKAVIKKESWEVPEIFRIMQKAGNIEENEMFRTFNCGIGMVLVVPEKEAEEIMIRLSGLNETAFVIGEVAKCDAGKECVELV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PHOLL
Sequence: MSGITAALVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGIILAEVAADGKFGALVELNCETDFVAKDAGFIAFGKEVMATVLADKISDIETLKAKFEEQRTALVAKIGENINIRRVSVLEGEQLGTYLHGARIGVLVAAEGANEELIKHVAMHIAASKPEYVNPSDVPADVVDREHQIQLDIAMQSGKPREIAEKMVSGRMNKFTGEISLTGQNFVMDPSKTVGDLLKENNATVTSFIRYEVGEGIEKVETDFAAEVAAMSK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMHA1_HUMAN
Sequence: MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
What is the function of this protein?
Precursor of the histocompatibility antigen HA-1.  More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells.  The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing.  The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor.  GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants.  Specifically, mismatching for mHag HA-1 which is recognized as immunodominant, is shown to be associated with the development of severe GVHD after HLA-identical BMT.  HA-1 is presented to the cell surface by MHC class I HLA-A*0201, but also by other HLA-A alleles.  This complex specifically elicits donor-cytotoxic T-lymphocyte (CTL) reactivity against hematologic malignancies after treatment by HLA-identical allogenic BMT.  It induces cell recognition and lysis by CTL.
What are the official names of this protein?
Rho GTPase-activating protein 45.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, ruffle membrane.
Protein: SAHH_BURP1
Sequence: MNAAVIDSHSAQDYVVADIALAGWGRKELNIAETEMPGLVQIRDEYKAQQPLKGARIAGSLHMTIQTGVLIETLKALGADVRWASCNIFSTQDHAAAAIVEAGTPVFAFKGESLDEYWEFSHRIFEWPNGEFANMILDDGGDATLLLILGSKAEKDRSVIARPTNEEEVALFKSIERHLEIDGSWYSKRLAHIKGVTEETTTGVHRLYQMEKDGRLPFPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTATGNYHVINHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWENIKPQVDHIIFPDGKRVILLAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELFTRGGEYANKVYVLPKHLDEKVARLHLARIGAQLSELSDDQAAYIGVSKAGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_SHEAM
Sequence: MSELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTALTLTRNLSPNPKVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSGSYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIGMFADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYSISAGLDFPSVGPQHAYLNATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RL1_HELAH
Sequence: MAKKVFKRLEKLFSKIQNDKVYGVEQGVGAVKSLASAKFDETVEVALRLGVDPRHADQMVRGAVVLPHGTGKKVRVAVFAKDIKQDEAKNAGADVVGGDDLAEEIKNGRIDFDMVIATPDMMAVVGKVGRILGPKGLMPNPKTGTVTMDIAKAVTNAKSGQVNFKVDKKGNIHAPIGKVSFPEEKIKENMLELVKTINRLKPNSAKGKYIRNAALSLTMSPSVSLDAQELMDIK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RPIB_MYCTU
Sequence: MSGMRVYLGADHAGYELKQRIIEHLKQTGHEPIDCGALRYDADDDYPAFCIAAATRTVADPGSLGIVLGGSGNGEQIAANKVPGARCALAWSVQTAALAREHNNAQLIGIGGRMHTVAEALAIVDAFVTTPWSKAQRHQRRIDILAEYERTHEAPPVPGAPA
What is the function of this protein?
Catalyzes the interconversion of ribulose-5-P and ribose-5-P.  It has not isomerase activity towards D-allose 6-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase B, Phosphoriboisomerase B.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.