PharMolix/UniProtQA huggingface dataset:
Protein: IFRH_TOBAC
Sequence: MVVSEKSKILIIGGTGYIGKYLVETSAKSGHPTFALIRESTLKNPEKSKLIDTFKSYGVTLLFGDISNQESLLKAIKQVDVVISTVGGQQFTDQVNIIKAIKEAGNIKRFLPSEFGFDVDHARAIEPAASLFALKVRIRRMIEAEGIPYTYVICNWFADFFLPNLGQLEAKTPPRDKVVIFGDGNPKAIYVKEEDIATYTIEAVDDPRTLNKTLHMRPPANILSFNEIVSLWEDKIGKTLEKLYLSEEDILQIVQEGPLPLRTNLAICHSVFVNGDSANFEVQPPTGVEATELYPKVKYTTVDEFYNKFV
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:19002761, PubMed:31276744).  Probable NADPH-dependent oxidoreductase that binds NADPH in vitro.  Does not seem to be involved in the NADPH-dependent reduction of phenylcoumaran benzylic ethers (PubMed:12369619).  Reductase that may be involved in a late step of tobacco alkaloid biosynthesis.  Maybe involved in either the formation of a nicotinic acid-derived precursor or the final condensation reaction of tobacco alkaloids (PubMed:19002761).
What are the official names of this protein?
Isoflavone reductase homolog A622, NtA622.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBY_PROMP
Sequence: MLRAIVVFAPIIAALAWVVFNIQKPAREQFNRDFLGKD
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RLME_SERP5
Sequence: MANKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGSGRIIACDILPMDPIVGVDFLQGDFRDELVLKALLERVGESKVQVVMSDMAPNMSGTPAVDIPRSMYLVELALGMCRDVLAPGGSFLVKVFQGDGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_ACTPJ
Sequence: MSELSTVARPYAKAAFDFALEQGQLDKWQEMLQFSAFVAENEQVAEYINSSLASGQISETFIKICGDQLDQYGQNFIRVMAENKRLAVLPMVFDTFVSLRAEHEAVKDVTIFSANELSQAQEDKIAKAMEKRLGQKVRLTNQIDNSLIAGVIIKYDDVVIDGSSRGQLNRLASALSL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PURNU_STAEQ
Sequence: MKERFIKKTHYLDYQFDEHTDIKLGFTTRENGLSPYPNHSFNMARYISDSAHHITHHQDILANLIGYPRDEWVFPIQTHDNRIVEVTSEHKGTNIDKLTDDLHGIDGMYTFDSHILLTMCYADCVPVYFYSESHGYIGLAHAGWRGTYGQIVKEMLKKVDFDYEDLKIVIGPATSNSYEINDDIKNKFEELTIDSTLYIESRGKNKHGIDLKKANALLLEEAGVPSKNIYITEYSTSENLDLFFSYRVEKGQTGRMLAFIGRK
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase SERP0752, Adenosine deaminase SERP0752, S-methyl-5'-thioadenosine phosphorylase SERP0752.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: MYG_MELME
Sequence: MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKGSEDLKKHGNTVLTALGGILKKKGHQEAELKPLAQSHATKHKIPVKYLEFISDAIAQVLQSKHPGNFAAEAQGAMKKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ORN_PSEMY
Sequence: MQNPNNLIWIDLEMTGLEPERDVIIEMATIVTDSELNVLAEGPVIAIHQSDETLAGMDEWNTRTHGQSGLTQRVRESRIDTATAEAQTIAFLEQWVPKGKSPICGNSIGQDRRFLYKYMPALEAYFHYRYLDVSTLKILAGMWAPQVKDSFQKTATHQALDDIRESIAELKHYRQHFLKA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIG_METTF
Sequence: MDDATNKKRKVFVSTILTFWNTDRRDFPWRHTRDPYVILITEILLRRTTAGHVKKIYDKFFVKYKCFEDILKTPKSEIAKDIKEIGLSNQRAEQLKELARVVINDYGGRVPRNRKAILDLPGVGKYTCAAVMCLAFGKKAAMVDANFVRVINRYFGGSYENLNYNHKALWELAETLVPGGKCRDFNLGLMDFSAIICAPRKPKCEKCGMSKLCSYYEKCST
What is the function of this protein?
DNA glycosylase that excises thymine from T/G mismatches and uracil from U/G mismatches (PubMed:8895589, PubMed:11788726).  Acts as a repair enzyme able to counteract the mutagenic effect of spontaneous hydrolytic deamination of DNA 5-methylcytosine (5-meC) residues that leads to the formation of T/G mismatches (PubMed:8895589).  May also repair U/G mismatches arising from hydrolytic deamination of DNA cytosine residues (PubMed:8895589).  G/G, A/G, T/C and U/C are minor substrates (PubMed:8895589, PubMed:11788726).
What are the official names of this protein?
Thymine/uracil-DNA glycosylase, DNA mismatch glycosylase, MIG, G/T mismatches repair enzyme, Type II nicking enzyme V.MthTI, V.MthTI.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: RLMN_CLOB8
Sequence: MNNLLDFTLEELKAWMKENGESAFRGQQILSWIYKGVKEFDNMKNIPKPLVQKLKENFFVGLPKIIEVYKSNIDGTEKFLLGFKDGNLIESVLMRYKHGNSICISTQVGCAMGCKFCASTIEGKVRNLTTGEILSQIMVVQDYINERISNVVLMGSGEPLDNYNNVIKFLEIVSAEYALNIGQRHITLSTCGIVPKIYELADKELSITLALSLHAFSNDKRKEIMPIANRYSIEEILEACRYYINKTNRRITFEYALVKDVNDGREDAKALGKLLKGMLCHVNLIPVNEIKENTYKRSSKKAIEDFSEILKNHGIEVTTRREMGSDINAACGQLRRSYINTQEIEGEQNGRFS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_NEIG1
Sequence: MSEQTQQQNSEEAVENVEAVETVETVGNADGVQEQAAAEPAYEDLQARIAELEAQLKDEQLRALANEQNLRRRHQQEIADTHKFAGQKFAVEMLPVKDYLEMALLDQSGNFDALKMGVQMTLNELQKAFDATQIKEINPKAGDKLDPNIHQAMQAVASEQEPNTVVGVMKKGYTLSDRVLRPAMVTVARKEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_XYLFA
Sequence: MSDFDRVRDYLTALQDRICNVVETIDGQSHFHEDHWQRTEGGGGRTRLLRDGAVFEQAGIGFSDVCGTHLPPSASVRRPELAGANWRACGVSLVFHPKNPFVPTTHLNVRYFRAERDGKQVAAWFGGGFDLTPFYPFDEDVVHWHTVARDLCAPFGDERYAAHKRWCDEYFVLRHRNETRGVGGLFFDDLDKDFERDFAYQRAVGDGFLDAYFPIVTRRHDTPYGDRERAFQLYRRGRYVEFNLLFDRGTLFGLQSGGRAESILISLPPLVRWEYGYHPLPGSAEARLADYLLPRDWLNESRICE
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLI_CHLRE
Sequence: MALNMRVSSSKVAAKQQGRISAVPVVSSKVASSARVAPFQGAPVAAQRAALLVRAAAATEVKAAEGRTGKELGQARPIFPFTAIVGQDEMKLALILNVIDPKIGGVMIMGDRGTGKSTTIRALADLLPEMQVVANDPFNSDPTDPELMSEEVRNRVKAGEQLPVSSKKIPMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILVGSGNPEEGELRPQLLDRFGMHAQIGTVKDPRLRVQIVSQRSTFDENPAAFRKDYEAGQMALTQRIVDARKLLKQGEVNYDFRVKISQICSDLNVDGIRGDIVTNRAAKALAAFEGRTEVTPEDIYRVIPLCLRHRLRKDPLAEIDDGDRVREIFKQVFGME
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step (By similarity).
What are the official names of this protein?
Magnesium-chelatase subunit ChlI, chloroplastic, Mg-chelatase subunit I-1, Mg-protoporphyrin IX chelatase subunit ChlI.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR3_PHAVU
Sequence: MGQKINPLGFRLGTTQSHDSIWFAQPTKYSENIQEDKKIRDWIKNYIQKNIRISSGVEGIGEIKIQKRIDLIQVIIYMGFPKLLIEGKPHKIEEFQTNMHKKLNCVNKKLNIAIVKITNAYKHPNILAEFIAGQLKNRVSFRKAMKKAIELTEQAGTKGVQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIEYCCYTVRTIYGILGIKVWIFSK
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IHFA_XYLFM
Sequence: MALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQRPGRNPKTGEEIPISARTVVTFRSGQKLKERVDAYVGSRQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RS4A_CLONN
Sequence: MARYIGATCRLCRREGMKLFLKGDRCYTDKCAFARRSYAPGQHGQGRKKLSNYGVQLREKQKARRIYGILEAQFRKYYEKAETMRGITGENLLKLLEMRLDNVVYKLGFGSSRAEARQLVTHGHFLVNGKKVDIISYQVSAGDVISVREKSRGTEKFKTFAENPKTLPAWLEGNIENFEGKVIAEPTRADIDVPVNETLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: OLF4_CANLF
Sequence: MELENDTRIPEFLLLGFSEEPKLQPFLFGLFLSMYLVTILGNLLLILAVSSDSHLHTPMYFFLANLSFVDICFTCTTIPKMLVNIQTQRKVITYESCIIQMYFFELFAGIDNFLLTVMAYDRYMAICYPLHYMVIMNPQLCSLLLLVSWIMSALHSLLQTLMVLRLSFCTHFQIPHFFCELNQMIQLACSDTFLNNMMLYFAAILLGVAPLVGVLYSYFKIVSSIRGISSAHSKYKAFSTCASHLSVVSLFYCTSLGVYLSSAAPQSTHTSSVASVMYTVVTPMLNPFIYSLRNKDIKGALNVFFRGKP
What is the function of this protein?
Putative odorant or sperm cell receptor.
What are the official names of this protein?
Olfactory receptor-like protein OLF4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y977_STAAB
Sequence: MAKQTTMKNAALKQLTKDADEILHLIKVQLDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVKLGLVDREDGKQIMLRLEKELSKLHEAFTLV
What are the official names of this protein?
UPF0358 protein SAB0977.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: TUS_SALPB
Sequence: MSRYDLVERLNGTFRQIEQHLAALTDNLQQHSLLIARVFSLPQVTKEAEHAPLDTIEVTQHLGKEAETLALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDNATQLDLENQIQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLTLINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQDIAALPQQARLKIKRPVKVQPIARIWYKGQQKQVQHACPTPIIALINTDNGAGVPDIGGLENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_DESDA
Sequence: MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHEDVAAHACKAGTPTMGGLLMLFSLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLRHHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIPFFKEVTFDLGWFYLPFGVFVMVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFCAALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLSVIVQVGYFRWTGGKRFFRMAPLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_CORDI
Sequence: MTSITHTISEIQKLTRQAISDARPVVLIPTMGALHEGHLSLVDTAYSLELDNPFVIMSIFVNPLQFAAGEDLDSYPRTLDADAAKLATHNHQVHAIFAPSPAEMYPLGPRTTITPGAAALRFEGATRPTHFAGVLTVVNKLFQITQCQHAIFGEKDFQQLALIRQMVADFNLPVHVHGSPLMRDHDGVALSSRNAYLSDTERVEARRISAALRQAAMFHVKHDIIAAAINAMAGMDIDYIDVVAPDFSEPTAGNELYGDARIITAVKVGSTRLLDNMAVNVEKPNA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_IDILO
Sequence: MLRIADRDFHSRLFIGSGKYSSADIMQKSLAASGSELVTLALKRVELERPTDDIVTPIQNLGLQLLPNTSGAKTAQDAIFAARLAREALGTHWLKLEIHPDPNYLLPDPIETLKAAETLVKEGFTVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLLTRDFLRIIIEQASLPVIVDAGIGAPSHAVEAMEMGADAVLVNTAIATANDPVAMSKTFRDAVIVGRQAFEAGLSQNASLKASASSPLTEFLESL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_LISMH
Sequence: MAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRAVHKYKDSREQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GLMU_STRPM
Sequence: MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAISPEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVTIFRANKEKVGAYILRDFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAKRLAHHPSRSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_PARP8
Sequence: MSGIDPKSFGKVAVLLGGASAEREVSLNSGRLVLQGLRDAGVDAYAFDPAERPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQLGIPTPPFEAVLRGDDYAARAQGIVAKLGLPLFVKPASEGSSVAVIKVKTADALVPALEEAVKFDKIVVVEKSIEGGGEYTACIAGDLDLPIIRIVPAGEFYDYHAKYIANDTQYMIPCGIAAEEEARLKKLARQAFDVLGCTDWGRADFMLDGEGNAYFLEVNTAPGMTDHSLPPKAARAVGISYQELVVKVLALTLKD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUT_RHIMB
Sequence: QAIVSKARRPYIL
What is the function of this protein?
Smooth muscle-contracting peptide.  Peptide action is not affected by tetrodotoxin, but is slightly mediated through the release of acetylcholine.
What are the official names of this protein?
Neurotensin, NT.
What is the protein family that this protein belongs to?
Belongs to the neurotensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_METPE
Sequence: MVLTKRIIPCLDLKDGRVVKGTHFVDLRDAGDPVELAERYNEQGADEVVFLDITASKEQRGAILSVISRAADQLFLPLTVGGGIRTIDDIQQLLRAGADKVSINTSAIKDPSLISDGAVRFGNQCIVVAVDVRRSTAANPDATVIHLPDGTTCWYEVVIYGGSTPTGIDAVRWVQDAEERGAGEILLTSMETDGTKNGFDLAITAAVSDAVSIPVIASGGVGTLADFYDGVTAGKADACLAASVFHYGEFTVRDVKTYLAGRGVPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3506_CAUVN
Sequence: MASLIDDDDGEFLIGRLLVAMPGIEDPRFERTVLYLCAHDEDAAMGLAVNRPVEGLTVFELLNRLGVRSEIQAPSDLVLLGGPLERERGFVLHTDDFSSPDSTLPVADGVALTATRDALDAMASAIKRPRKSLLALGYAGWGPGQLEQELRDNVWLICDADEGLLFDEDHEHKWTRALAKLGITADHLSATAGRA
What are the official names of this protein?
UPF0301 protein CCNA_03506.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: S23A1_RAT
Sequence: MKAQEDPGSSKQHECPDSAGTSTRDQQAPLPAEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQHMISQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSMPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSETLASLKSYDFPFGMGMVKRTTFFRYIPICPVFRGFSKTENQPAVLEDAPDNTETGSVCTKV
What is the function of this protein?
Sodium/ascorbate cotransporter (PubMed:10331392).  Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (By similarity).
What are the official names of this protein?
Solute carrier family 23 member 1, Na(+)/L-ascorbic acid transporter 1, Sodium-dependent vitamin C transporter 1.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WRKY8_ARATH
Sequence: MSHEIKDLNNYHYTSSYNHYNINNQNMINLPYVSGPSAYNANMISSSQVGFDLPSKNLSPQGAFELGFELSPSSSDFFNPSLDQENGLYNAYNYNSSQKSHEVVGDGCATIKSEVRVSASPSSSEADHHPGEDSGKIRKKREVRDGGEDDQRSQKVVKTKKKEEKKKEPRVSFMTKTEVDHLEDGYRWRKYGQKAVKNSPYPRSYYRCTTQKCNVKKRVERSYQDPTVVITTYESQHNHPIPTNRRTAMFSGTTASDYNPSSSPIFSDLIINTPRSFSNDDLFRVPYASVNVNPSYHQQQHGFHQQESEFELLKEMFPSVFFKQEP
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring stress-responsive cis-acting element.  Functions as positive regulator of salt stress response.  Binds the W box of LTI78/RD29A stress-response gene and directly regulates its transcription under salt stress.  Functions antagonistically with VQ9 to regulate sodium and potassium homeostasis under salt stress by regulating the expression of downstream SOS (SALT OVERLY SENSITIVE) stress-responsive genes.  The DNA-binding activity of WRKY8 is decreased by VQ9 (PubMed:23451802).  Functions as negative regulator of basal resistance to the bacterial pathogen P. syringae and as positive regulator of resistance to the fungal pathogen to B. cinerea (PubMed:20367464).  Functions as positive regulator of defense response againt tobamovirus (TMV) by regulating both the abscisic acid and ethylene signaling pathways.  Positively regulates ABI4 expression and negatively modulates ACS6 and ERF104 expression by directly binding to the W box consensus motifs within their promoters (PubMed:23650359).
What are the official names of this protein?
WRKY transcription factor 8, WRKY DNA-binding protein 8.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-c family.
What are the subcellular locations of this protein?
Nucleus.