PharMolix/UniProtQA huggingface dataset:
Protein: CYB_BUGNE
Sequence: MKNQMMKHNPMGKMANSLIQLACPKNISALWSFGSLLGLCLITQILTGIFLAMFYIPNIYQAFDSAIYISRDVNFGWLIRSIHANSASMFFICIYTHTGRGIYYSSHQMKETWMVGVTLLLITILTAFLGYVLPWGQMSFWAATVITNLLSAIPYLGSTIVNWIWGGFSVSNATLTRFYALHFLFPFLISALSLMHIIFLHQSGSSNPLGLNSNNETMKFHIYFSAKDLIGVILLWIMLGSVVLLKPNLLIDPENFIPANPLVTPTHIQPEWYFLPMYAILRSIPNKLGGVLALIMSIAILYFLPMMNKPITKSASMNPKNKIAFWLLVTNFIVLMWIGSKPVESPFEEIGQIMTVTYFSIYMIMSKN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RAN_PONAB
Sequence: MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
What is the function of this protein?
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs.  Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis.  Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way.  Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport.  Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins.  RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.  Required for normal progress through mitosis.  The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.  Acts as a negative regulator of the kinase activity of VRK1 and VRK2.  Enhances AR-mediated transactivation.
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
Protein: GLMU_PSELT
Sequence: MRCIVLAAGMGVRMNSKYAKVTHTVCGKPMIRWILDTVLNLLDKVCVVVGHDADSVKKLLPENVEVVHQSQQLGTGHAVMSARNFIDPADNLLILYGDMPLITEGTIQKIINSHNLSNCDATVVSVEMNDPTGYGRIVRDKSGKFVKIVEESEASNREKAIVEVNTGVYIFNGRKLLEVLPMINCKNKKGEYYLTDVFAFLERVNIYKSERSCEFIGINNRIQLAQAEKFRRQWILEELMIKGVTIVDPETTYIDADVKIGRDSIIYPMSFIHGDTKIGEDCIIGPMTRIIDSYIGDRVTIVRSECKGARIMSDVSVGPFSRLREGTVLCNGVKIGNFVEIKNSEIDQNTKAQHLTYLGDAVVGKSVNIGAGTITCNFDGKRKNQTVIEDEVFIGSNTALVAPVKVEKGAFVAAGSTINRNVPAWSLAIARARQEIKLNWVIDKRKKEED
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_CAUVC
Sequence: MPAVVRGGPPKPRRPRAEAPASPSKGKPAPRKAQPAAKLHAARGVGLSPTVALSVAGAALGLGLVVMLATGHRAERLGASMVRGVDNTFASAGFRLKTVHIRGASATAQADILKASGLYLDQPTLGMDLADVRDRVQGVGWVKDAKVVRMLPDTVLIAVEERPALAVWQNHGRMKVIDSEGQVITEADPARFPQLPLVVGQGADQAAGLILPAVASRPRLRDRLEAMVRVDERRWDLRLKDGSLIQLPAIDEESALIQLDQLDQRQRILDMGFARIDLRDPEMVAVRPRDAVLPGQPAADGA
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: TAMO_DROME
Sequence: MSDFVPHDLIPDLWDEILRRHWMFLETEESIEKLEERKQLEGCLKEFLCVVQHDRKFFLPETGHVLRRSVLELPDFSAQNAIVAFETISQYANNLFTKPWRKEYRTLKTYSGCFQHDIQSRLLDAEQLFLAMGYRRAAEDTFVLEGPICPDQVTNVSRDAMAAYVECQIMKHIYAGVTAAGYVCTWKDILQFRERYVGGTSTTIKEMVRQLSEKRVRMEQPPMQENTYSNVVSAAPTACGMRSNNVAHHPSSSGTCALHPNGLNEAGKYLPPYPAPPPQQPHLPGPLMTHSRSLDHYQEPQAHLPHRHSFDQQLQQQCQLPHVYEAPYDCLDGLSMGSSASYAAVTGAYNAPGNRYPLPYNISSQLNAPYASPADFYGNGQHTNMYATLGKTGPAHSCDLHRRQPNTSAAAAAALAAMQHRQSTYPPDHHLIDFDERAHLTQHDFGTHDYDPQYAELRGQVQPSMRGNPVAMYATYGGYDLPTTLPQAPPPTGQDMYIYARPVPKSSRMRALAEAGGINSTDKHPRSAEKQSTMDNNRKMHKELKERNSRTAPAKRSGTERDIPTTISDLNSYDSASLDGFVALDSSSSPPLMPKVQEGVGSFESWNYVFKNLERSGYTKDLGDREDLLVQSLDLGSLSITNGGAAPPAEKRREATNPTNGEKARTLDKKSGTGRREAKVVQAPAPSPLPNSSSAGVKKVKSALKTAVVDNRGTGSRQRTGAVPKQPPNVSPQLIVTSPNEWSCSFCTFLNPDTKRICEMCCRSKDFNLEAASAASSSAAAAAASAASVSHASSTCV
What is the function of this protein?
Has an essential role during oogenesis and embryogenesis, perhaps in modulating the levels of nuclear import of additional proteins.  Modulates the nuclear import of dorsal (dl), Dif and male specific lethal 1 (msl-1).  Negatively regulates nuclear import of dl and controls the accumulation of dl in the nucleus after immune challenge.
What are the official names of this protein?
Protein tamozhennic.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG11_VANPO
Sequence: MSSNIINAITGELITIDITLFISLNEFKKFLINRWQIDFNNLLLLLPFGNKINDRIFIDLIGKKNDQSTIYVFDRRLFSLVNNPDNELSSDYLTNIKNLLKGINHPTNNLNQLVKPVNSPYEEVEINEKFLNYHTITSLITTNLGWLSALEIDMHYFQIQISDTLDYIKNIIESLKICQNYLELYCYDVENLYNSNVKFLNQLANNEILKNWLNYYDNILTKLSDINGNKLSSYLNKNELVSISSKIEELDQRVNSNLKKFKIVIDKNIDLRNNINKEISSLSEKITPSSEKYKLEETMLEKFTELVKNLRNDSKVILEKDENEFDKNYMQNLAKSLEKDKKVTVTNLLTISKALYSQANDISEIKSKLQVDSIKLFGQISFIQIETLNIKKLLLNELNKDLEKYQGFELKLAHVQDIPLVYGLYSIENYRRESWVLQINYKHLDFNKSLKTIVEKEKSTRNKWVDNFGSTAVYFTEDMDTLRDFNYLNNIAKGNQSMIKKLEELFKNISNESHNKNLVFIETYIKEVEDLDLDKDVIELFKRYLAVAQGFVIEQPSTKNIISDKETGELINGYQSRIKKLELLLHSARYSNVESWPTGLLNYSNVKLFRNNVATVNSKLSLQSDYMGNISYGSDQLRIKELENVNKQYKTDFKALTDENKLLKDKVTKFNTDISDIQIERNAYKETLTKLNEELSRLTSIEGDFEKHKGEKEIELKIKIDGLVDSNKTLLNQISDLKIESKELESSNRDLLAQLNQKREEHKVLEDSLKQRENEGLRYKDEYEAKLKELTEKFEADRRALEDEIKAAKEQNMKESMEQQTEQSANQSIDQSIEQSTEQSTEQSTEQSMEQSMEQSMEQSVEQSMEHSMEHSMEQSEKQNMGQNDATIDNQSIETPTSEDMHSLDEQSPESQLLKSNTTELQPIKSQELAEDSKAIELKNIQEMLVSKLYEIFSSNVFILENIGLLLTFDEHDNFQIRRVKGLKKNLNQSVLEETGLLNEIEMPVKSDVFSEVKTLFSNYKETFDSRSYISLLSKINQLYDCKLYETAVIKRFEDIELLAKKLAKENKAKKNLFEKYRCERITLKNFEVGDLALFLPTRENCITEDVSVASWNSSFSSVDLSTPPPFGEPITNQSHSGTAKDKNKHNLEKRPWAAFTAFEETARYFLKDPENIPNNREWFVGKIMHLQRFVVEDHISNPYKLPKGAVWFQVTATVVSHQ
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for the Cvt vesicles completion (By similarity).
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: Y715_MYCCT
Sequence: MIKKSSIKKYFKTIKDSSIKDISVDQQYPFDFKFYKPKVEGMIILFSLVILPLITVIFLNVFKTQLNITDERLGLIFQLSSILFTLVGAIIFWSRNPMSFWKSGVGILFGFPIFLQLFGLAFGLLANLVGVFNNNNNNAWSDIYNLLVQSVAEILVIIFAFSKINNLKSKVKKTFKENKKLLIPIAIAFAIVAFFVGNTLYSLIITELKLNLGESKNQEGLVSPFKVQGITKYIYMVLFIILTVFIAPLCEEIVARQALFTGVSNKVLSIIVSSLYFGILHISSGDVYNIFPYVIGGFFFSLAFSFSKGNLSYCWLSHSFYNLISVVLIIASLYIK
What are the official names of this protein?
Uncharacterized protein MCAP_0715, ORF1.
Protein: LIN29_CAEEL
Sequence: MDQTVLDSAFNSPVDSGIAGTTTGSGSTTHFGVGTNFKVSVRSSSRSTDGTDSTDGANSDNVTGSTGSTPAHHSITNLNMALSQHSIDSATAASSTNPFPHFNQADLLNFHQNSLLPHHMFSQFGRYPQFEQKPDVGVLQQQMQMREAKPYKCTQCVKAFANSSYLSQHMRIHLGIKPFGPCNYCGKKFTQLSHLQQHIRTHTGEKPYKCKFTGCDKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFTDEQSLLDHIPKHKESKHLKIHICPFCGKSYTQQTYLQKHMTKHADRSKASNFGNDVVPADPFDPSLLSWNPMQGMGDNAHDSSSFNISSLTDQFAANTMIGSQSTNYNPAFQNSAFSQLFNIRNNRYLSEYPTSTKNGERAPGFNMITPLENIQRYNGSSSSATAVVTATGSAVVSSTPSSTSSSSAGSSSSQGGVFNPQSLINNMKNHSY
What is the function of this protein?
Required for seam cell fusion.
What are the official names of this protein?
Zinc finger transcription factor lin-29, abnormal cell lineage 29.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in nuclei of hypodermal cells in a temporally restricted fashion, beginning during the larval L4 stage.
Protein: DNLI4_PONAB
Sequence: MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDAFHKNQKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHGDAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHSDAVELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKTDIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMIKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHKKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRGKASGKLASKHFYVGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFEDVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSKNIRVKNIILSNKHDVVKPAWLLECFKTKSFVPWQPHFMIHMCPSTKEHFAREYDCYGDSYFVDTDLNQLKEVFSGIKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDLYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVIIGEDHSRIADFKAFRRTFKRKFKILKESWITDSIDKCELQEENQYLI
What is the function of this protein?
DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination.  Catalyzes the NHEJ ligation step of the broken DNA during DSB repair by resealing the DNA breaks after the gap filling is completed.  Joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction.  LIG4 is mechanistically flexible: it can ligate nicks as well as compatible DNA overhangs alone, while in the presence of XRCC4, it can ligate ends with 2-nucleotides (nt) microhomology and 1-nt gaps.  Forms a subcomplex with XRCC4; the LIG4-XRCC4 subcomplex is responsible for the NHEJ ligation step and XRCC4 enhances the joining activity of LIG4.  Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.  LIG4 regulates nuclear localization of XRCC4.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TP8L2_SALSA
Sequence: MESFSSKDMAMKAQKKILSHMASKSMVQMLIDDTSSEILDELYRISKEHSGNRTEAQKVVKDLVKVVVKVGVLFRHNRFSKEELSLAQDFKKKLHQGVMTAISFQEVEFTFDKAVMTELLTDCRDILLKLVEKHLTLKSFGRIRHVFNHYSDPDLLTNLYTPGGPLWPNLTKICNGLNKLVEEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits jun/ap1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: VPS10_KOMPG
Sequence: MWIERNLIASILLFSTSAYAAFKPRIVKKEFDDLLNPIYFNDSSTVLGLVDQTLLISNDDGKSWTNLQEVITPGEIDPLTIVNIEFNPSASKAFVFTASKHYLTLDKGSTWKEFQIPLEKYGNRIAYDVEFNFVNEEHAIIRTRSCKRRFDCKDEYFYSLDDLQSVDKITISDEIVNCQFSQSSTSSDSRKNDAITCVTRKLDSNRHFLESNVLTTLNFFKDVTSLPASDPLTKMLIKDIRVVQNYIVLFVSSDRYNKYSPTLLFISKDGNTFKEASLPDSEGTSPSVHFLKSPNPNLIRAIRLGKKNSLDGGGFYSEVLQSDSTGLHFHVLLDHLEANLLSYYQIENLANLEGIWIANQIDTSSKFGSKSVITFDAGLTWSPVTVDEDEDKSLHIIAFAGENSLYESKFPVSTPGIALRIGLIGDSSDALDIGSYRTFLTRDAGLTWSQVFDNVSVCGFGNYGNIILCCSYDPLLRSEPLKFRYSLDQGLNWESIDLGFNGVAVGVLNNIDNSSPQFLVMTIATDGKSSKAQHFLYSVDFSDAYEKKICDVTKDELFEEWTGRIDPVTKLPICVNGHKEKFRRRKADAECFSGELFQDLTPIEEPCDCDPDIDYECSLGFEFDAESNRCEPNLSILSSHYCVGKNLKRKVKVDRKSKVAGTKCKKDVKLKDNSFTLDCSKTSEPDLSEQRIVSTTISFEGSPVQYIYLKQGTNTTLLDETVILRTSLRTVYVSHNGGTTFDRVSIEDDVSFIDIYTNHYFPDNVYLITDTDELYVSDNRAISFQKVDMPSRAGLELGVRALTFHKSDPNKFIWFGEKDCNSIFDRSCQTQAYITEDNGLSFKPLLENVRSCYFVGTTFDSKLYDFDPNLIFCEQRVPNQRFLKLVASKDYFYDDKEELYPKIIGIATTMSFVIVATINEDNRSLKAFITADGSTFAEQLFPADLDFGREVAYTVIDNWESKTPNFFFHLTTSEDKDLEFGALLKSNYNGTTYTLAANNVNRNDRGYVDYEIVLNLNGIALINTVINSKELESEQSLETAKKLKTQITYNDGSEWVYLKPPTIDSEKNKFSCVKDKLSLEKCSLNLKGATDRPDSRDSISSGSAVGLLFGVGNVGEYLNQDSSGLALYFSKDAGISWKEIAKGDYMWEFGDQGTILVIVEFKKKVDTLKYSLDEGETWFDYKFANEKTYVLDLATVPSDTSRKFIILANRGEEGDHETVVHTIDFSKVHQRQCLLNLQDSNAGDDFEYWSPKNPSAVDGCMLGHEESYLKRIASHSDCFIGNAPLSEKYKVIKNCACTRRDYECDYNFALANDGTCKLVEGESPLDYSEVCRRDPTSIEYFLPTGYRKVGLSTCEGGLELDNWNPVPCPGKTREFNRKYGTGATGYKIVVIVAVPLLVLLSATWFLYEKGIKRNGGFARFGVIRLGEDDDDDLQMIEENNTDKVVNVVVKGLIHAFRAVFVSYLFFRKRAAKMFGGSSFSHRHILPQDEDAQAFLASDLESESGELFRYASDDDDAREIDSVIEGGIDVEDDDEENINFDSR
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: MLECA_XENLA
Sequence: MLSIRTVLGPLATILLTVLGPFGAHGSGLADKVIWAVNAGGESHVDVHGIHYRKDPLEGRVGRASDYGMKLPILRSNPEDQVLYQTERYNEDSFGYDIPIKEEGEYVLVLKFAEVYFAQSQQKVFDVRVNGHTVVKDLDIFDRVGHSTAHDEIIPISIKKGKLSVQGEVSTFTGKLSVEFVKGYYDNPKVCALFIMKGTADDVPMLQPHPGLEKKEEEEEEEEEEGSTSKKQINKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL
What is the function of this protein?
Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan.  May play a role in the early steps of protein N-glycosylation.  Can bind di- or higher oligomers but not monomers of glucose, including maltose, maltotriose, maltotetraose, maltoheptaose, nigerose, kojibose, cellobiose and isomaltose, although based on their subcellular locations, these are unlikely to all be physiological ligands.
What are the official names of this protein?
Malectin-A.
What is the protein family that this protein belongs to?
Belongs to the malectin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: Y2435_LISMH
Sequence: MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
What are the official names of this protein?
UPF0145 protein LMHCC_2435.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL13_ACIF5
Sequence: MKTYSAKSHEVQGDWFVVDATDKVLGRLSVELAKRLRGKHKPEYTPHADTGDYIVVINADKIAVTGNKAKDKIYYHHTGYVGNLKSASFEKMKETHPERIIELAVKGMLPKNPLGRAMFKKLKVYTGSEHPHSAQQPQPLNV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TTCA_ALCBS
Sequence: MSDNADTKKRTRLNKLQKKLRRETGRAIADFNMISEGDKVMVCLSGGKDSYTMLEILRNLQHSAPVNFELVAVNMDQKQPGFPEHILPEYLEKEGVAYHILEKDTYSIVKEKVPEGKTTCGLCSRLRRGSLYGFAEEIGANKIALGHHRDDIVETLFLNMFYGGKMKAMPPKLRSDDSRNVVIRPLAYCREKDIIEFSALKEYPIIPCNLCGSQKNLQRQVIKEMLQQWDKQQPGRIENIFAAVQNIAPSQLADTRLFDFENLEQGQQQGGDQAHRLDVVNLFG
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1656_PASMU
Sequence: MPSFDIVSEITLHEVRNAVENANRDLTNRWDFRNVQAAIELNEKNESIKVSSESDFQVEQLVDILRNACIKRGIDSGSLDIPTEYEHSGKTYSKEIKLKQGIASEMAKKITKLIKDSKLKVQTQIQGEQVRVTGKSRDDLQAVIQLVKGAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein PM1656.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: AQP9_MILTA
Sequence: MGAFVNTKVYIENKNIRDWLSEALSMFMYMSLLLGSAATGHFSGREDDALFGVIFQGFSITFGIYIGGAMSGAIINPALTLAVALLGKISWRKCIVLQSAQYIGSFIASAVVYLIYNDSLDAFGAGANFTATEPGVFRKDVAGIWSTFPKTYLKERGAIFNQIFCSMLLTFGFLAISDYKNFRPSKGLFPIAVGLLVMTVFLAFSYSTGAAMNPARDFSPRLWSLIIGYGIEVFSYNQYEWFWIPWLMPYVGAMLGALIYQLLIGAQWSKGQKGESKHKDP
What is the function of this protein?
Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis (PubMed:23761966).
What are the official names of this protein?
Aquaporin-9, AQP-9.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUBCD_GEOMG
Sequence: MEETEIPQNIVLTRLDDLINWGRANSLWPMFFGLSCCFVEMMTSFTSRYDISRFGAEVLRGTPREADLMVIAGTVFKKMAPSILRLYEQMAEPKWVISMGSCANSGGMYDVYSVVQGVNQIIPVDVHVPGCPPRPEAFLQGVMLLQEKIRREERPARKVLHMAGGTEGTTRPVLVDGVTKSRDTRGPGMEGIAIRGTPVQHPRFWMSRSDEMWRPPAPRHDYPDFGLAGELETIFGGRVAVEQAATDMLTYRCPPELVPEVLRHLKSRSSAPFRRLEDVVCVDESCRRERERFPDFTVNYHLLNFDIPGHLRIKTELMGETPELPSATGVFPAADWYEREAFDMYGIRFAGHPNLRRILMPPDWEGHPLRKEHPFRATEMPPYTTDDARRHQALPASDFFDRIDEETLIINLGPQHPGTHGIIRFILKLDGEEIVDMDTDIGYHHRGAEKIGERQHWNQFIPYTDRIDYLAGVQNNLAYVNSVERLCGITVPDRAITIRVMLAELFRIASHLVWLGTFAADVGAMTPVFYTFTDREKIFDIIEMVTGGRMHPSWFRIGGVTEDLPEGWDGAVKEFLDWMPGRLKEYEDLLKENPIFKARLKGVGVITKDEAMEWGITGPNLRACGMAWDLRKKIPYNGYQHFHFEIPTEEGGDCWARYRIRVEEIRQSLHIVAQCRKEMPAGRWITDDYRYVLPKKRDTLHDIESLIHHFINATRGMAPPRGENYSAIEAPKGENGYFVVSDGLNVPYRVRIKTPSFPHIQALPLMSRGWLVADFLAIIGSIDFVLADLDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B/C/D, NADH dehydrogenase I subunit B/C/D, NDH-1 subunit B/C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLPDH_CALMK
Sequence: MFDVAIIGAGVIGCSIARELSKYNLNVALIEKENDVGNVTTKANSAIIHAGYDAKPGTLKGKLNAKGNLMFDELCRELEVPFKRVGSLVLAFDDDEMKTLGKLYEQGIQNGVPELYILSKEKVLEMDPNISDNIKGALYAKTGGIIGPWEFTIALAENAVENGVNIFLSNEVVDIEKKDFGYRIITNKDTYDTKYVVNCAGLYADKINNMVSNNKMEIIPRRGQYYLLDKTVGNLVKYVIFQCPSKLGKGVLVTPTVHGNLLIGPDAEDLIDKTALNTTSEGLNFIVEVARRSVKTLPLNMAITNFAGLRARTERDDFIIEEAVDAKGFINVAGIESPGLSSAPAISLYVIDILKNIAKKIEKKENFNPYRRAIPKFIELSEDEKNELVKKDKRFGKIICRCESITEGEIVSAIHRNVGARTVDAVKRRVRAGMGRCQGGFCSPRVIEILARELGVEMTEIEKDHEGSYILTGPTKSEVQ
What is the function of this protein?
Catalyzes the dehydrogenation of glycerol 3-phosphate to dihydroxyacetone phosphate (PubMed:34555022).  Is probably involved in anaerobic glycerol metabolism (Probable).  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCPIP), but not with NAD or NADP.  Also displays a very low oxidase activity in vitro on glycerol 3-phosphate with O2 as the electron acceptor, but this activity is most likely not physiological (PubMed:34555022).
What are the official names of this protein?
Glycerol 3-phosphate dehydrogenase.
Protein: CH60_LACLS
Sequence: MSKEIKFSSDARTAMMRGIDILADTVKTTLGPKGRNVVLEKSYGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPVGIRRGIELAAETAVASIKEMAIPVHDKSAIAQVATVSSRSEKVGEYISDAMERVGSDGVITIEESKGMQTELDVVEGMQFDRGYLSQYMVSNTEKMVAELDNPYILITDKKISNIQEILPLLEQILKTNRPLLIVADDVDGEALPTLVLNKIKGVFNVVAVKAPGFGDRRKAQLEDLAILTGGTVITEELGLDLKDATLEALGQAAKATVDKDHTTIVEGAGSVDAISDRVAIIKAQIEKTTSDFDREKLQERLAKLAGGVAVVKVGAATETELKAMKLLIEDALNATRAAVEEGIVSGGGTALVNAIAALDKLSEEGDIQTGINIVRRALEEPVRQIAANAGYEGSVIIDKLRSEKVGTGFNAATGQWVNMIEEGIVDPAKVTRSALQNAASVAGLILTTEAVVANKPEPAAPAMPPMDPSMGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPR_GEOTN
Sequence: MKSTEQHYSIKEAMLFSQRIAQLSKALWKSIEKDWQQWIKPFNLNINEHHILWIAYHFKGASISEIAKFGVMHVSTAFNFSKKLEEKGLLSFSKKQDDKRNTYIELTEKGEEVLMKLMETYDPTRNAVFNGALPLRELYGKFPEILEMMCIVRNIYGDDFMEIFERAFENIKEDFVEQDGKLVKRAPKAEEHEKELASPG
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: EFTU_LIMRD
Sequence: MAEKEHYERTKPHVNIGTIGHVDHGKTTLTAAITKVLAAKGLAKAEDYADIDAAPEEKERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVQYIVVFLNKTDLVDDDELVDLVEMEVRDLLSEYDFPGDDVPVVRGSALKALEGDPEQEKVILHLMDVIDDYIPTPKRPTDKPFMMPVEDVFTITGRGTVASGRIDRGTVKVGDEVEIVGLTEDVLKSTVTGLEMFHKTLDLGEAGDNVGVLLRGISHDQIQRGQVLAEPGSIQTHKNFKGEVYVMTKEEGGRHTPFFSNYRPQFYFHTTDVTGTIELPDGVEMVMPGDNVTFTVNLQKPVALEKGLKFTIREGGHTVGAGVVSDILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.