PharMolix/UniProtQA huggingface dataset:
Protein: XAC2_XYLAI
Sequence: GFVALLKKLPLILKHLP
What is the function of this protein?
Antimicrobial and mast cell degranulating peptide which probably acts by forming pores in membranes (PubMed:28546807).  Active against Gram-negative bacterium E. coli NBRC 14237 (MIC=3. 12 uM), against Gram-positive bacteria S. aureus NBRC 12732 (MIC=3. 12 uM) and M. luteus NBRC 12708 (MIC=6. 25 uM) as well as against yeast S. cerevisiae NBRC 10217 (MIC=25 uM) (PubMed:28546807).  Has hemolytic activity (at 100 uM) (PubMed:28546807).  In the context of inflammation and cancer tests, is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:36548715).  In addition, prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  Does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:36548715).
What are the official names of this protein?
Antimicrobial peptide Xac-2, Xac2, Xylopinin.
What is the protein family that this protein belongs to?
Belongs to the xylopin-like family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Assumes an amphipathic alpha- helical conformation in a lipid environment.
Protein: MICU3_HUMAN
Sequence: MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIPVAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR
What is the function of this protein?
May play a role in mitochondrial calcium uptake.
What are the official names of this protein?
Calcium uptake protein 3, mitochondrial, EF-hand domain-containing family member A2.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single-pass membrane protein.
Protein: GST_XANCP
Sequence: MKLYTKPGACSLADHIVLRWSCLPFELTVVDAATMKSPDYLRLNPAGAVPLLVVDQWALTQNAAILNYIADTAPLTGLGGDGTARSRAEINRWIAFVNADLHPTFKPLFGSTAYLQEDALIQRSHEDARTKLRTLYTRVDAHLQGRNWLAGDTHTGADAYLFVTLRWAHKAGVDLSGLSALDAFFQRMLADADVQAALQAEGLN
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase GST-4.5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APGM_THET8
Sequence: MDLFPVLKELAQKTPSKILLIVLDGVGGLPLEPGGPTELEAAKTPNLDRLAEESALGLLTPVYPGLAPGSGPGHLALFGYDPFRYVVGRGALSALGLGADFREGDVALRGNFATLDPEGKVVDRRAGRPPTEENQRVIAKLKEAIPRIEDVEVLFYTESEHRFLVILRGEGLEDKVTDTDPQKTGLPPLKAKALDEASERTARLVNLLSERIREVLKDEPRMNGALFRGASKKPSFPRMQEVYKLTPAAIASYPMYKGLASLVGMEVLPVEGEGDALEGKLKALKENWGRYDFFYFHVKKTDAMGEDGNFHGKVEKVELFDALLPEILALGPDVLAITGDHSTPALLKAHSWHPVPLLLKAPYLRADEARRFTEREAQRGSLGHLRGVELMPLLLAHAGKLLKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: B3GN7_RAT
Sequence: MSLWKKTLYKSVCLALALLVAVTVFQRSVTPGQFLQDPLPPTLGPPKTGSLVNPNSFWKSSKDVVAPTPTVPRGPQVWDVVTTNCSINVNLTHQPWFQNLEPHFRQFLAYQHCRYFPMLLNHPEKCAGDVYLLVVVKSVITQHDRREVIRQTWGHEWESAGPDRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWDFLDSFFNLTLKEIHFLKWLDIYCPNVPFIFKGDDDVFVNPTNLLEFLSDRQPQENLFVGDVLKHARPIRKKDNKYYIPAVMYSKATYPPYAGGGGFLMSGSLARQLHHACDTLELFPIDDVFLGMCLEVLGVKPTGHEGFKTFGISRVRGSRMNKEPCFYRSMLVVHKLLPAELLAMWDLVHSNLTCSLKFQVL
What is the function of this protein?
N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans.  Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer (By similarity).  Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (By similarity).  May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (By similarity).
What are the official names of this protein?
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, BGnT-7, Beta-1,3-Gn-T7, Beta-1,3-N-acetylglucosaminyltransferase 7, Beta3Gn-T7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: DEF4_TRIKH
Sequence: RDCTSQSHKFVGLCLSDRNCASVCLTEYFTGGKCDHRRCVCTKGC
What is the function of this protein?
Plant defense peptide.
What are the official names of this protein?
Defensin Tk-AMP-D4.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: TRMD_BORBR
Sequence: MRFDVVTLFPDMFGLVRDQGVTGRAHAQGLWALHAWNPRDFTQDVHRTVDDRPYGGGPGMVMMAAPLEAAVAAAQAARAAQGLQAAPVILLSPAGRRYDQAEATTLAAGTGAIFICGRYEGVDQRFIERCVTHELSLGDFVLSGGELAALAMMDAAVRLLPGVLNDGDSALQDSFNAALDGLLDSPHYTRPEVYEGVPVPQPLLSGHHANIARWRREQSLRLTASRRPELIERARGEGRLSKADERFLAGLAGERKS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SALAI
Sequence: MVIVPRVAIGVDTHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAADLGDLGANFGVGQPEWSGASGVALLTESASRVRAAGYAIGNVSVQVIGNRPKIGSRRAEAQRVLSGAVGAPVSISAATTDGLGFPGRGEGLTGIAVALVYEAPDA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ERCC2_CRIGR
Sequence: MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAFPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQDASLPHCRFYEEFDAHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQSEETLRRVEQIAQQL
What is the function of this protein?
ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATP-dependent helicase activity of XPD/ERCC2 is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.  XPD/ERCC2 acts by forming a bridge between CAK and the core-TFIIH complex.  Involved in the regulation of vitamin-D receptor activity.  As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation.  Might have a role in aging process and could play a causative role in the generation of skin cancers.
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPD, TFIIH subunit XPD, CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, Xeroderma pigmentosum group D-complementing protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: YEM8_SCHPO
Sequence: MTKEWECRREQIIELSKINGMTIRELQARMSKMYKFDASIRSYKRVLARWGIRVHRQRFVSPRTEEAAARTASGDVSKALDELVTQLFHARQSDKDSLAQIEANFGLKLSKRALHYRRKRLALKRPPPDSHDSPNNSIPLMANSCLLSADNSSSSTTSNPNVAPPISTLPDPVATISSSSSSHLDMGAIHPPHHSSLPPHMGVDPSTMADAHNAHSSLTPPQSGYSSMPSLPYLQQPFQIPSQRFSRQQQSHPFPAAQHAVNGQPQALYPFIYQSRNVPMGSTMFASSNQSAAHPDGNNALPMDNTHANISYMQSSQSMPVNSYSYDRYTPNQPSYLESKPGNHQPSYTSEQPMYSTASVPQQISNGPTAVNGLPMNSYTPHSNHLHSPSPNSNSGPTDSLSAPNSTSSPSMAHANGASFASQYPSLNKSIFPASYSSSAEDGQNMQAPAHAYMQSSIYGVNQEQKSEYPSNLSMQSSMSIKDPSQLQRIHLYPQHSQYDPNGMTMRDHYSERIEPEAKPSDETLTVRSSRDLSVHNVGTLPVLSAAAATQAAMPHTMGPSAHDSASAPSPHMQSQQALPYQYYNPLPAMADPAQNVPQQLPPPIHSHLSDDQHIQYSYPNTFVNRFPQNIHHPSANLLDASAALNPVQNPLLMPQQNHEHSPLVRSDAALHDHGPLLPVYPDVDSRFV
What are the official names of this protein?
Uncharacterized protein C29B12.08.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_DEHMB
Sequence: MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRENGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTTRPLSVPVGRGTLGRIFNVLGEALDNRGDVKSEKTMPIHRLAPGMDELESSAQVLETGIKVIDLIAPFARGGKIGALGGAGVGKTVLIQELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVLLFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAMIALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYKVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRFLTQPMFVSEVFTGRPGQYVSLTETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYH_SHESM
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRASVAAYGYSEIRTPIVENTDLFKRSIGEVTDIVEKEMYTFEDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEVYGIGSADIDAEVLMLSARLWEKLGISEHVTLELNTLGDPAERAAYREALIAFLEQHKDKLDEDSQRRMYSNPLRVLDSKDPQVQSILGDAPALMDYLGEESSQHFAQLRELLDAVGIQYRVNPRLVRGLDYYNRTVFEWVTNSLGSQGTVLAGGRYDGLVAQLGGKDTPAVGFAMGLERIVLLLETLELTQDIPAAVDVYVAAMGDSCLVEAIKVAQELRSTLPTLRVMSHCGGGNFKKQIKRADKSGAQVALLIGEEELAEGVVTVKYLRNDNEQQRVARNALSAFLAELTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSL5_ORYSJ
Sequence: MPPPETSSAAAPSPPSPDPLPPWRDQLTLRGVAVAAVLGSLLCVVIHRLNLTVGVIPALNVASGLLAFFLATAWRGAAAVLGLGHHRGRPFTRQENTVIQTCAIACGSLAFSGCSSSYIFAMDRKTYELVGQDYPGNRMEDIRDPSLGWMIGFMFLIALIGPFSIVMLRKVMVIDYKLAFPGGTATALMINSLHGKTEADLAGRKVHCLVKYMSLSFGWSFFKWFFSGVGDSCGFDNFPSFGIEAFKNTFYFNFNPSYVGYGLISPHIVNCSVFLGSVISWGFLWPFIAKQAGDWYPDNLSNTDFRGLYGYKVFIAISVILGDGLYNLVKVFLIIAKEICNARSKEHDLPVQALLQDDDSSRQLLDEKRQTEIFLKDSIPTWLAVSGYIVLAAISTVAVPIIFPQLKWYLVLVCYFLAPAIAFCNSYGMGLTNLNLAPTYGKIALFVFASLVGSDGGVIAGLAACGVIMSIVCSTADLMQDFKSGYLTLSSPRSMFISQMIGVALGCIIAPLTLWLFWTAFDIGDPDGEYKAPFAIIFREMAIIGIEGFAALPRHCLEICCVFFLAALIINLMKDVVPNHVSRFIPIPMAMAVPFYIGAYFGVDMFIGTLILFAWQKIDRREADDYAVAVASGLICGDGVWSIPSAVLSILGVDPPICMSFRPSSASV
What is the function of this protein?
May be involved in the transport of nicotianamine-chelated metals.
What are the official names of this protein?
Probable metal-nicotianamine transporter YSL5, Protein YELLOW STRIPE LIKE 5, OsYSL5.
What is the protein family that this protein belongs to?
Belongs to the YSL (TC 2.A.67.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HBL_ZEAMP
Sequence: MALAEADDGAVVFGEEQEALVLKSWAVMKKDAANLGLRFFLKVFEIAPSAKQMFSFLRDSDVPLEKNPKLKTHAMSVFVMTCEAAAQLRKAGKVTVRETTLKRLGATHLRYGVADGHFEVTGFALLETIKEALPADMWSLEMKKAWAEAYSQLVAAIKREMKPDA
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.
What are the official names of this protein?
Non-symbiotic hemoglobin, Hbt, ZEAmp GLB1.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: XYLA_PSEPF
Sequence: MPYFPDIERIRYEGPASDSPLAFRHYDADKIILGKPMREHLRMAACYWHTFVWPGSDVFGAGTFKRPWQHAGDPMELAIGKAQAAFEFFSKLGIDYYCFHDTDVAPEGNSLKEYRNHFAQMIDHLERHQEESGIKLLWGTANCFSNPRFAAGAASNPDPEVFACAAAQVFSAMNATQRLKGANYVLWGGREGYETLLNTDLKREREQLGRFMRMVVEHKYKIGFKGDLLIEPKPQEPTKHQYDYDSATVFGFLQQFGLEKEIKVNIEANHATLAGHSFHHEVATAVSLGIFGSIDANRGDPQNGWDTDQFPNSVEEMTLVTYEILKAGGFGNGGFNFDSKVRRQSLDETDLFHGHVGAMDVLALSLERAAAMVQNDQLQRLKDQRYAGWQQPFGQSVLAGDFNLQSLAEHAFANELNPQAVSGRQEMLENVVNRFIYR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLD10_MOUSE
Sequence: MSAAQGWDRNRRRGGGAAGGASGVSGAGAAGGGRGTGQLNRFVQLSGRPHLPGKKKIRWDPVRRRFIQSCPIIRIPNRFLRGHRPPPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLVLHGNNLLVFGGTGIPFGESNGNDVHVCNVKYKRWALLSCRGKRPSRIYGQAMALINGSLYVFGGTTGYIYSTDLHKLDLNTMVWTQLKPNNLSCDLPEERYRHEIAHDGQRIYILGGGTSWTAYSLNKIHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPATMPEPVYFHCAAVTPAGCMYIHGGVVNIHENKRTGSLFKIWLVVPSLLELAWEKLLAAFPNLANLSRTQLLHLGLTQELIERLK
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (By similarity).  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms (By similarity).  The CRL2(KLHDC10) complex specifically recognizes proteins with a proline-glycine (Pro-Gly) at the C-terminus, leading to their ubiquitination and degradation (By similarity).  Participates in the oxidative stress-induced cell death through MAP3K5 activation (PubMed:23102700).  Inhibits PPP5C phosphatase activity on MAP3K5 (PubMed:23102700).  Acts as a regulator of necroptosis (PubMed:27631783).
What are the official names of this protein?
Kelch domain-containing protein 10.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: TUSC_SALCH
Sequence: MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUX6_HUMIN
Sequence: MAKFFLTAAFAAAALAAPVVEERQNCAPTWGQCGGIGFNGPTCCQSGSTCVKQNDWYSQCLPGSQVTTTSTTSTSSSSTTSRATSTTRTGGVTSITTAPTRTVTIPGGATTTASYNGNPFEGVQLWANNYYRSEVHTLAIPQITDPALRAAASAVAEVPSFQWLDRNVTVDTLLVETLSEIRAANQAGANPPYAAQIVVYDLPDRDCAAAASNGEWAIANNGANNYKGYINRIREILISFSDVRTILVIEPDSLANMVTNMNVAKCSGAASTYRELTIYALKQLDLPHVAMYMDAGHAGWLGWPANIQPAAELFAKIYEDAGKPRAVRGLATNVANYNAWSISSPPPYTSPNPNYDEKHYIEAFRPLLEARGFPAQFIVDQGRSGKQPTGQKEWGHWCNAIGTGFGMRPTANTGHQYVDAFVWVKPGGECDGTSDTTAARYDYHCGLEDALKPAPEAGQWFQAYFEQLLRNANPPF
What is the function of this protein?
Plays a central role in the recycling of plant biomass.  The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Exoglucanase-6A, 1,4-beta-cellobiohydrolase 6A, Avicelase 2, Beta-glucancellobiohydrolase 6A, Exocellobiohydrolase 6A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase A) family.
Protein: RS4_PROM9
Sequence: MSRYRGPRLRVTRRLGELPGLTRKASKKSNPPGQHGQARRKRSEYAIRLEEKQKLRFNYGVSEKQLVRYVKKARAQEGSTGTNLLRLLENRLDNVCFRLGFGGTIPGSRQLVNHGHVTVNGKVLDIAGYQCKSGDVIGIKENKASKKLVEGNIEFPGLANVPPHLDLDKPKLTGKITGKCDREWVALEINELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y4OR_SINFN
Sequence: MAISSNTSRTTRKLLWTLFWCVLAFVYLFPYTWMVLTGFRHGVDTISMPPRFIFEPTLAGFKHLFEVTGFQKYIINSAVVTIVSVVLVIAVSAPAAYALAHVTKRGGTLLVAILVARIIPGIAIGVPVYLLATRLHQLDTYQALIIINVAVNIPFAIWLMRSFFMEVHPTLREAAISDGCSEWQVFTKIMMPLVLGGMLATAVFVFIAVWNEFLFALILTTSVSPTAPLAMLGFRTQYGVQWDAVGAAAFLVSTPVIAFAFIMQRYLVQGLTMGSVK
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4oPQRS.  This system probably transports a sugar-like molecule.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein y4oR.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2489_GEOSW
Sequence: MSSFDQTMQFHFSEEPAETNIREVLLTVYDALQEKGYNPINQIVGYLLSGDPAYIPRHKDARTLIRKVERDELIEELVKFYLQGQRKD
What are the official names of this protein?
UPF0297 protein GWCH70_2489.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: NUP59_YEAST
Sequence: MFGIRSGNNNGGFTNLTSQAPQTTQMFQSQSQLQPQPQPQPQQQQQHLQFNGSSDASSLRFGNSLSNTVNANNYSSNIGNNSINNNNIKNGTNNISQHGQGNNPSWVNNPKKRFTPHTVIRRKTTKQNSSSDINQNDDSSSMNATMRNFSKQNQDSKHNERNKSAANNDINSLLSNFNDIPPSVTLQDWQREDEFGSIPSLTTQFVTDKYTAKKTNRSAYDSKNTPNVFDKDSYVRIANIEQNHLDNNYNTAETNNKVHETSSKSSSLSAIIVFGYPESISNELIEHFSHFGHIMEDFQVLRLGRGINPNTFRIFHNHDTGCDENDSTVNKSITLKGRNNESNNKKYPIFTGESWVKLTYNSPSSALRALQENGTIFRGSLIGCIPYSKNAVEQLAGCKIDNVDDIGEFNVSMYQNSSTSSTSNTPSPPNVIITDGTLLREDDNTPAGHAGNPTNISSPIVANSPNKRLDVIDGKLPFMQNAGPNSNIPNLLRNLESKMRQQEAKYRNNEPAGFTHKLSNWLFGWNDL
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  May have a mitosis control function (By similarity).
What are the official names of this protein?
Nucleoporin ASM4, Nuclear pore protein NUP59.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: Y181_BUCAI
Sequence: MTDEEKNLIENLFHRLKKTELNSPERDDAADELIQRLAKKQPTSSYYMAQTILIQETAIKKMSIELEELRKKIKILNREETNKKPSFLSNFFKKKSPSEIISNDNNILKKKENILPSNYSSSPISPTTQTSPVINNTRSSSFLGNALQTATGVAGGMILGNMLMNVFSHTKPEEDIFDTVKQSSSDEYTENNFLNNNTDNDLINYSYNESDINFRESSEESINNNVDDTDDIDNDNFI
What are the official names of this protein?
Uncharacterized protein BU181, yba2.
Protein: PPAC_LISMC
Sequence: MTKTLVFGHKNPDTDTICSAISYAELKKAQGADIEAVRLGELNSETAFVLDYFQVTAPRLVQTVANEVSEVALVDHNERQQSVDDIDDVTVTAVVDHHRIANFETSDPLYYRAEPVGCTTTILLKMFRENEVEVSKTVAGLMLSAIISDTLLFQSPTCTEEDKVAAQKLAQIADVDIQSYGMEMLKAGADVSKKTVAELLLDAKEFNMNDNKVEIAQINVVDVNDVLSRRAEVEALMTQNIVDKGLDLYLFVITNILTNDSVGIAIGSKTAVVEEAYGVKFVENQAPLKGVVSRKKQVVPILTDTFAK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXXS2_ARATH
Sequence: MGNHCTRIPCCKKVCSCICCCNRRNKTQARSQKGSYFIKGKVHPVSRMEKWEEKITEANSHGKILVVNFKASWCLPSKTILPIYQELASTYTSMIFVTIDVEELAEFSHEWNVDATPTVVFLKDGRQMDKLVGGDAAELQKKTAAAANLLLRQS
What is the function of this protein?
Possesses low disulfide reductase activity, but efficient protein disulfide isomerase activity.  Does not possess deglutathionylation activity.
What are the official names of this protein?
Thioredoxin-like protein CXXS2, AtCXXS2, Mono-cysteine thioredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R14_PONPY
Sequence: MGGVIKNISTFVLIVEFIIGNLGNSFIALVNCIDWVKRRKISLVDQLLTALAISRISLVWLIFGSWCVSAFFPALFATEKMFRMLTNIWAVTNHFSVWLATGLGTFYFLKIANFSNSIFIYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYGGNKTCSSDSNDFTRFSSLIALTSSVFIFIPFILSLAIFLLLTFSLWKHCKKMQHTVKASGDASTKAHRGVMQTVIAFLLLYPIFSLSFFIAVWTSGWLEENLIILSQVMGMAYPSCHSCILILGNKKLRQASLSVLWWLKYRFKDGEPSGHKGFRESS
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 14, T2R14.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.