PharMolix/UniProtQA huggingface dataset:
Protein: CASP2_MOUSE
Sequence: MAAPSGRSQSSLHRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTLSDIQHVLPPLSCDYDTSLPFSVCESCPPHKQLRLSTDATEHSLDNGDGPPCLLVKPCTPEFYQAHYQLAYRLQSQPRGLALVLSNVHFTGEKDLEFRSGGDVDHTTLVTLFKLLGYNVHVLHDQTAQEMQEKLQNFAQLPAHRVTDSCVVALLSHGVEGGIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHTQSPGCEESDAGKEELMKMRLPTRSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCQQLYLFPGYPPT
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (PubMed:7958843).  Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (By similarity).
What are the official names of this protein?
Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: PDXH_ECOLC
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TR13C_HUMAN
Sequence: MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPGLLFGAPALLGLALVLALVLVGLVSWRRRQRRLRGASSAEAPDGDKDAPEPLDKVIILSPGISDATAPAWPPPGEDPGTTPPGHSVPVPATELGSTELVTTKTAGPEQQ
What is the function of this protein?
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS.  Promotes the survival of mature B-cells and the B-cell response.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: JIP3_DROPS
Sequence: MMDNDDALLNNGGPQSGAETVYGTEDNNMVMSEKNDQVVSIVQQLAGSIYQEFERMINRYDEDVVKNLMPLLVNVLECLDASYRINQEQDVELELLREDNEQLVTQYEREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEERETDLKKEYNKLHERYTELFKNHVDYMERTKMLMGSTHSQMSTASDRMEVSRARLNPVARSSGPVSYGFASLENSVMLDTETICSVGSQSDDSGPPSLQNELDMSLPSTAERGAATDSLQQQHQATSPQSPPDTSPVVPNVPPANVGRSTTKKEQRSDNNLYQELSFQDNEESEENEIVTGCWVHPGEYASSANDNYFGMGKEVENLIMENNELLATKNALNIVKDDLIVKVDELTGEVEIVREELSAMQQSRTKLRQRISELEEELKKTKEQVKQQNTEQEENDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDKKSKQSIWKYFSNLFTPSNRPTERIADGLGGGPMFRNTGGGSPAHSHGSPSRGSGDNRLTLAGSQPPMHPASAGLANALVMPKDYSEDGGSERISARRREQYRQLRAHVQKEDGRLHAYGWSLPINKANQEANPSRHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKDGQSLIPADSPYAPKSTLKITEITSPTAEQSVEALDRQIARASLETLEPETQLSSFVWICTSTHAASTVSVVDANQSATVLDAFPICSSHLLCIASVQGAMESDYALLEQSEVVKAGEMLQRPGEGTELLGKVEFVRVKPKSEDEQNSNSKPQQQQQDEEEAKEATEKSNEPLPPVNAEEPLVNVEAIKIRQALPGAPQRLSSGNSGSDGNQANNNNSSSTGSVLFATKSLNPILGTKEREDPPMTSVGPTMWMGAQDGWLYVHSGVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQLAVFRRQTDGQWDLNSYHLVTLGDRNHSIRCLCVAGERIWAAHRNKIFIVDPISLNIVHSLDAHPRKESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWIGTSNGVIISVPLAEVQQKTSSDPHGQMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNGGLTFVNKRPDMLVMCGGEGYIDFRINDNDMENSIQLEPNQTIENRGDKSYLIVWHVSQR
What is the function of this protein?
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module.  May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.  Syd is required for efficient kinesin-I mediated axonal transport (By similarity).
What are the official names of this protein?
JNK-interacting protein 3, Protein sunday driver.
What is the protein family that this protein belongs to?
Belongs to the JIP scaffold family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARBA_CELJU
Sequence: MPTHHPITRQHWHHSWLSALALLCASLACGAKQVDVHDPVMTREGDTWYLFSTGPGITIYSSKDRVNWRYSDRAFGTEPTWAKRVSPSFDGHLWAPDIYQHKGLFYLYYSVSAFGKNTSAIGVTVNKTLNPASPDYRWEDKGIVIESVPQRDLWNAIDPAIIADDHGQVWMSFGSFWGGLKLFKLNDDLTRPAEPQEWHSIAKLERSVLMDDSQAGSAQIEAPFILRKGDYYYLFASWGLCCRKGDSTYHLVVGRSKQVTGPYLDKTGRDMNQGGGSLLIKGNKRWVGLGHNSAYTWDGKDYLVLHAYEAADNYLQKLKILNLHWDGEGWPQVDEKELDSYISQRLK
What is the function of this protein?
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall.  Catalyzes the cleavage of the terminal alpha-(1->5)-arabinofuranosyl bonds of linear arabinan and carboxymethylarabinan to produce almost exclusively arabinotriose.
What are the official names of this protein?
Extracellular exo-alpha-(1->5)-L-arabinofuranosidase ArbA, ABF, Extracellular arabinan exo-alpha-(1->5)-L-arabinosidase ArbA, Arabinosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMH_ECO5E
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_FUSNN
Sequence: MKDKEIKEEVLKEEINKEVNEKKKCECEEGKEEAHEHKNDEHACCGKHNHKEEIEKLKAEIEEWKNSFLRKQADFQNFTKRKEKEVDELKKFASEKIITQFLGSLDNFERAIESSSESKDFDSLLQGVEMIVRNLKDIMSSEDVEEIPTEGAFNPEYHHAVGVETSEDKKEDEIVKVLQKGYMMKGKVIRPAMVIVCKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM144_CAEEL
Sequence: MSIAVGLSACALSSVLFGSMFVPVKKCHSGNGIFVQWIMSTAILLVGIVVYSTQGFPEFEPLAMLGGMFWALGNATAVPIMNTIGIGMGMLVWGTTNCVAGWAAGRFGLFGINSTVPEYPFLNYFGLVLVVFGGFLFSQIRPNEPQTASERSPLMVAPDDDLTDDVAPDDSDIVVPRGGAVPTRAHRNQKRLLAIITSLVAGVFYGFTFVPVIYIQDHPEIYPTAPKTGLGYVFSHYIGIFCTASALMIGYVIYSRNNPFASSRLVGPSMTAGSMWGIAQASWFVANDNLSQAVSFPIISMVPGVIAALWSVFYFRDISGSRNLRLLSIAVAITLIGAICVGVSK
What are the official names of this protein?
Transmembrane protein 144 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM144 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PCOTH_HUMAN
Sequence: MWILSNLMGTSEEGNLLSTVSPTVKALFGKTRVSPIFPFSPRSPFQPLIPRTPGSPWGPVGPASPLGPGFPIGPMGPGKPVGPKGPMLPLGPSGPVGPTSPLFPFCP
What is the function of this protein?
May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway.
What are the official names of this protein?
Prostate collagen triple helix protein, C1QTNF9B antisense RNA 1, C1QTNF9B antisense gene protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_PYRFU
Sequence: MREITPKRIMEMKGKEKITMITAYDYPSALLADKAGFDIVFVGDSLGMVVYGEQNTLNVTMDQMIFHTRAVAKAVKRALVLADMPFGSYEVSVEEGVKNAIKLIQAGADAVKIEGGYDHRKLVKKLVRMGIPVMGHTGLTPQRYLRLGGYRIMGENEEEVEEILRDAKALEKAGAFAVVLEFVLADVAKLVTEEVSIPTIGIGSGPYVDGQVLVWHDVLGLYESSPPFAKRYANLREEILRAISEFRKEVKEGKFPGKEHYWEYQDKETFNRIKENVMRKLRL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACL_ESCF3
Sequence: MDYEFLRDVTGVVKVRMSMGHEVIGHWFNEEVKENLALLDEVEDAARTLKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRDFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: RK20_DAUCA
Sequence: MTRIRRGNIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALVSSHRDRDKQKRNFRRLWITRINAVIREIGVSYSYSRLIHALYKKQVLLNRKILAQIAISNKNCLYMISNEIIKEVDWKESTGII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TI10A_XENLA
Sequence: MDPVKAQQLAAELEVEMMADMYNSLLRMTGACHKKCVPPHYKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSLQDEELMKKMQQGVTST
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10-A.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: MGN2_HUMAN
Sequence: MAVASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:29301961, PubMed:30705154).  Plays a redundant role with MAGOH in the exon junction complex and in the nonsense-mediated decay (NMD) pathway (PubMed:23917022).
What are the official names of this protein?
Protein mago nashi homolog 2.
What is the protein family that this protein belongs to?
Belongs to the mago nashi family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1080_METJA
Sequence: MEGKIMNIKHKIPILLLVLYIALGVFIQYNGISEFKSLPSPIYGGDYYYQMGVIWHIRDGGNPLESSSMIGGMPGYLPLYAYLCAKFCDLLNLDTMKGILYFSVVLFIMTSVIWFYLFRVLFKDDWVALIEVVLA
What are the official names of this protein?
Uncharacterized protein MJ1080.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCPB_STRSV
Sequence: MSKLAEIEALLFVAGEDGLKVHQLAEILSLPPTGVIQSLEKLAEQYEVNPDSSLTLLETSKTYKLVTKPEFAEILRAYSRAPINQSLSRAALETLSIIAYKQPITRVEIDDIRGVNSSGALAKLLAFELVREDGKKEVIGRPNLYVTTDYFLDYMGINHLDELPIVEETELVAEESQLFIERTDIDENQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RECF_BEUC1
Sequence: MYVSDLALTDFRSYADLVIGLEPGITAFVGPNGQGKTNLVEAIGYLGTFSSHRVSGDAALVRWGAERAVVRAKVVRRARPTLVELEIVAGRANRARVDRSPVSRVREAAGIARSVIFAPEDLALVKGDPDGRRRFLDDLLVQLSPRLAGVRSEYERVLRQRTALLKSAGPARRRSGDGEPAALRTLDVWDGHLARAGAELVAARVRLVQDLRPHVGATYEQVSAAQSEARISYRASVEEARPDDAPTEVVESVETELTRADLVEARLLEAMARLRTREIERGVSLVGPHRDDLVLTLADMPAKGYASHGESWSYALALRLASYALLRDDGEAGGGGEPVLVLDDVFAELDARRRTRLASIVASAEQVLVTAAVAEDVPEELEGARMDVMGGEVLRVR
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAP9_ADE12
Sequence: MNGTTQNNAALFDGGVFSPYLTSRLPYWAGVRQNVVGSTVDGRPVAPANSSTLTYATIGPSPLDTAAAAAASAAASTARSMAADFSFYNHLASNAVTRTAVREDILTVMLAKLETLTAQLEELSQKVEELADATTHTPAQPVTQ
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: MDH_METS4
Sequence: MARKKIALIGAGQIGGTLAHLAGLKELGDVVLFDIADGVPQGKGLDIAESAPVDGFDAKYAGASDYAAIAGADVVIVTAGVPRKPGMSRDDLIGINLQVMEKVGAGIRTHAPNAFVICITNPLDAMVWALQKFSGLAPNKIVGMAGVLDSARFRHFLAEEFQVSVEDVTAFVLGGHGDDMVPLVRYSTVAGVPLPDLVKMGWTTQEKLDAMVERTRKGGGEIVNLLKTGSAFYAPAASAIAMAESYLKDKRRVLPCAAYLTGQYGIDGLFIGVPIVIGENGVERVVEVEFSAEEKAMFDKSVASVKGLVEACKGINAALA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: ATG12_YEAST
Sequence: MSRILESENETESDESSIISTNNGTAMERSRNNQELRSSPHTVQNRLELFSRRLSQLGLASDISVDQQVEDSSSGTYEQEETIKTNAQTSKQKSHKDEKNIQKIQIKFQPIGSIGQLKPSVCKISMSQSFAMVILFLKRRLKMDHVYCYINNSFAPSPQQNIGELWMQFKTNDELIVSYCASVAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes.  ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E2 activity.
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Note=Localizes to the isolation membrane (IM), a membrane sac which is generated from the pre-autophagosomal structure (PAS). Ultimately, the IM expands to become a mature autophagosome. Localizes also to a dot at the junction between the IM and the vacuolar membrane, termed the vacuole-IM contact site (VICS).
Protein: KTHY_PSEF5
Sequence: MTGLFITLEGPEGAGKSTNREYLAERLRAAGIEVLLTREPGGTPLAERIRDVLLTPVEEVMNADTELLLVFAARAQHLATVIRPALERGAVVLCDRFTDSTYAYQGAGRGLSLARIAALEDFVQGELRPDLTLVFDLPVDVGLARASARGRLDRFEQEGQAFFQKVREAFLARAAAAPQRYVLVDAAQPLAQVQQSLDSLLPQLLERARG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: APT_CITBB
Sequence: MEDLKSIIRNIPDFPKKGILFKDITTLLGDAKSFQRMVDLLSHRYVGQKIDKVVGVEARGFIIGAALAYKLGAGIVLVRKPGKLPSKTRSKTYDLEYGTDTLEIHTDAFNKGDRVLIADDLLATGGTMAAVVDLISSMDVELVECCFMAELEFLEGGKKLPEGKVFSLLKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_ERWT9
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTQQAIDAIMDGMNWLNLDWDEGPYYQTKRFDRYNTVIDQMLEAGSAYKCYCSKERLETLRENQMANGEKPRYDGRCRDGHEHHAENEPCVVRFRNPQEGSVIFDDQIRGPIEFSNQELDDLIIRRTDGAPTYNFCVVIDDWDMEITHVIRGEDHINNTPRQINILKAIGAQVPVYAHVSMILGDDGKKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSIDEMKKLFELDVVSKSASAFNTEKLQWLNHHYINSLAPEYVATHLQWHIEQENIDTRTGPQLAQLVKLLGERCKTLKEMAASCRYFYEEFDEFDADAAKKHLRPVARQPLEVVRDKLAAMSDWTAEGVHQAIQAAADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGQARSVARIEKALAYIATREA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEDA_ECOBW
Sequence: MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.
Protein: Y402_SHEB2
Sequence: MGIKDWPEGEGPRDKLLQKGAGQLSDAELLAVLLRNGLAGLNAVDLARSLISEFGGLRNLLCAPRNQVCRLPGVGPVKYAQLQAAAELARRVAQENLQRGQVLTNPDLTRDYLMRQLADRSYEVFAVLLLDSQHRVIQFVELFRGTIDSASVYPREVVSLVLEKKAAAVIVCHNHPSGIAEPSQADRRITERLKNALATIDVSLLDHMVVGDREIVSFAERGWIN
What are the official names of this protein?
UPF0758 protein Sbal223_0402.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: F16PA_METC4
Sequence: MTKPYGSSLDDHLDAEVAREPSLADTAATIRALAAAAIDVSETVGRGSLAGDLAAQGEHNSDGDVQKALDVIAHKRFMQALEEAPVAQVASEEAEDVVTLKAGAPLAVAIDPLDGSSNIGVGMVVGTIFGIRPVTPGEDPNASFLTPGTTQTAAGFVVYGPATTFVVTLGNGTRIFTLDRTDNVFRLTHDAMKIVPSASEYAINASNVRHWDGPVKSYIEDCLRGSEGPRDRDFNMRWTAALVADAQRVLIRGGVFLYPGDNRKGYAQGRLRLLYETAPIAFLIEQAGGGATDGQGRILERVATKIHERSPLVFGSTEEVECVAKYYDGRQPSAGRSPLFGQRGLMRS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORAI3_MOUSE
Sequence: MKGGEGDTGEQAPLNPEVDSPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLENDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPMGKPAPVVPMSQVPPVTVSLSLASNLTPSSASITTSQQPSKACPPRQVCDSAHGPGWQAAMASTAIMVPVGLVFMAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV
What is the function of this protein?
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
What are the official names of this protein?
Protein orai-3, Transmembrane protein 142C.
What is the protein family that this protein belongs to?
Belongs to the Orai family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMFO_STRPS
Sequence: MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGFSQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAHYITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAC_BPSFV
Sequence: MHKSNCFDTARLVAAMMVLVSHHYALSGQPEPYLFGFESAGGIAVIIFFSISGYLISKSAIRSDSFIDFMAKRARRIFPALVPCSILTYFLFGWILNDFSAEYFSHDIVRKTISSIFMSQAPDADITSHLIHAGINGSLWTLPLEFLCYIITGVAVAHLKNGKAFIVILLVFVSLSLIGSVSENRDVMFSIPLWLYPLRGLAFFFGATMAMYEKSWNVSNVKITVVSLLAMYAYASYGKGIDYTMTCYILVSFSTIAICTSVGDPLVKGRFDYSYGVYIYAFPVQQVVINTLHMGFYPSMLLSAVTVLFLSHLSWNLVEKRFLTRSSPKLSLD
What is the function of this protein?
Antigenically converts S. flexneri serotype X to 3a, Y to 3b, 1a to 1b and 4a to 4b by O-acetylating the O-antigenic polysaccharide chain.
What are the official names of this protein?
O-acetyl transferase, O-antigen acetylase.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Host cell inner membrane; Peripheral membrane protein. Note=Inner membrane- associated.