PharMolix/UniProtQA huggingface dataset:
Protein: KASA_MYCTE
Sequence: MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the elongation of long chain acyl-ACP substrates by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Involved in the initial extension of the mycolate chain and forms monounsaturated fatty acids that averaged 40 carbons in length.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 1, Beta-ketoacyl-ACP synthase 1, KAS 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_DESPS
Sequence: MLQQAQTTSRNTLLDRVDSPKDIRQLTHDDLIILAAEIREKIIDTVSKTGGHLAPSLGVVELTLALHYVFNTPTDKLVWDVGHQSYAHKILTGRRKQFDTLRQYRGMSGFPKRGESDYDAFETGHSSTSISAALGMTLAMDLLQQDNKAIAVIGDGSMTAGMAFEALNHAGHLDKNLIVILNDNEMSISPNVGALSSFLSRKLTGKTMRRVKSHLVEKLQDSDVGENILNVLRKSEESFKSFFTPGMLFEAFKFDYIGPIDGHDIDALISTLNTVRDTAKGPALIHVLTKKGKGYLPAEENPDAFHGVGPFNRQTGKIIKKKGPASYTTVFGQTMLELGKKNKNIVAISAAMVAGTGLTPFSEAYPDRFFDVGIAEQHAITFAAGLASQGMRPVVAIYSSFYQRAMDQIIHDVCIPNLPVTLAIDRAGVVGDDGPTHHGIFDISFLRFIPNLTIMAPKDEAELQQMLVTATGHDGPTAIRYPRGAGEDVSTSQEIESIPILEIGRGELLREGDDILLLPIGNRVYPAMRAAEELAKQGISASVINPRFIKPLDAELICQQAKKTGRIITIEDNTLCSGFGSAVLELLSQKSLYGIKTKILGHPHAFVEHGPQKTLWENSGITSRGIIMAALDLLQKETDPSVANE
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CODY_STAES
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPREYTEELMNVKQTESNIDIDNELTVFPPENREVFLNSRTTIFPILGGGERLGTLVLGRVQDDFNENDLVLGEYAATVIGMEILREKHNEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKDKFLDELEKNK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLGD_SALPA
Sequence: MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNRRILPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGATRDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDNRRHGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_SHIB3
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHLQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_SHEAM
Sequence: MYQTTAALRSAFLEYFRQQGHQVVDSSSLVPGNDPTLLFTNAGMNQFKDCFLGMEKRSYVRAATAQRCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEDAIRFAWEFLTGTLKLPKEKLCVTVYHTDDEAFDIWNKQIGVPAENIIRIGDNKGAPFASDNFWQMGDTGPCGPCTEIFYDHGEHIWGGRPGSPEEDGDRFIEIWNIVFMQYNRQSDGTLDPLPKPAVDTGMGIERISAIMQGVHSNYEIDIFQKLIAKAAEIIGVSDLENKSLRVIADHIRSCAFLVADGVMPSNEGRGYVLRRIIRRAVRHGNKLGATDTFFYKLVPTLIEAMGDAAKELKATQTIVEKALKAEEEQFARTLERGLGMLDAALADLKGDTLDGETVFKLYDTYGFPVDLTADVCRERNLKVDEEGFNAAMAEQRSRAQAAGQFSADYNAALKIDTATDFCGYTELAAESKVVALYRDGESVDAAEAGAVLVVVLDNTPFYAESGGQVGDKGQLLAEGVEFNVADTQKFGQGIGHKGQLALGSIKVGDSLKAMVDKKLRHRTELNHSVTHLLHAALRQVLGTHVTQKGSLVDPERLRFDFSHFEGVKREELKAVEDLVNTQIRRNHELNFAEMDIEEAKAKGAMALFGEKYDSKVRVVTMGDFSIELCGGTHVGRTGDIGLFKITSEGGIAAGIRRIEAVTGAAAMAYVAQQQAELEEAAALLKGDVASVVAKLKAQLDKARQLEKENAQLKDKLAAAASADLAGDAQEINGVKVLVKRLEGVEAGALRGLQDELKQKLKSGVVLLAIGSGDKVNLIAGVTQDLTGKVKAGELVAMVAAQVGGKGGGRPDMAQAGGSEPAKLDGALASVVPWLNERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEF2D_MOUSE
Sequence: MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSSVPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQPPQQPQPPQPPQSQPQPPQPQPQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
What is the function of this protein?
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes.  Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.  Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.  Plays a critical role in the regulation of neuronal apoptosis.
What are the official names of this protein?
Myocyte-specific enhancer factor 2D.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus. Note=Translocated by HDAC4 to nuclear dots.
Protein: DAD2_CANAL
Sequence: MSKTNTAIYQKIAEKRANLERFREFKELTDDLVLQLESIGDKLETMNGGTASVALILANWKSVVQSISLASLALMKESNDNNKEAFPEPLVRVRVGQSNEENQDEEEADEEEGVRDSEEVEESTE
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit DAD2, Outer kinetochore protein DAD2.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: Y1104_HAEIN
Sequence: MTNKVNSYGWKALIGSAVGYGMDGFDLLILGFMLSAISADLNLTPAQGGSLVTWTLIGAVFGGILFGALSDKYGRVRVLTWTILLFAVFTGLCAIAQGYWDLLIYRTIAGIGLGGEFGIGMALAAEAWPARHRAKAASYVALGWQVGVLGAALLTPLLLPHIGWRGMFLVGIFPAFVAWFLRSHLHEPEIFTQKQTALSTQSSFTDKLRSFQLLIKDKATSKISLGIVVLTSVQNFGYYGIMIWLPNFLSKQLGFSLTKSGLWTAVTVCGMMAGIWIFGQLADRIGRKPSFLLFQLGAVISIVVYSQLTDPDIMLLAGAFLGMFVNGMLGGYGALMAEAYPTEARATAQNVLFNIGRAVGGFGPVVVGSVVLAYSFQTAIALLAIIYVIDMLATIFLIPELKGKALD
What are the official names of this protein?
Putative metabolite transport protein HI_1104.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS8E_METHJ
Sequence: MQWQGRSVRKSTGGRYSPSRGKRRREIGSAPAETHIGIDRRKISRTYGGNNKVRALRCEYAAISNAKTGETKKVKIETVEENAANPNYVRRNLLTRGAIIRTELGRARITSRPGQHGVINAVLIE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: CA162_HUMAN
Sequence: MGGNGSTCKPDTERQGTLSTAAPTTSPAPCLSNHHNKKHLILAFCAGVLLTLLLIAFIFLIIKSYRKYRRERLPISPGPLLRWVPLLSGTMADHSKPQAPDPHSDPPAKLSSIPGESLTYASTTFKLSEEKSNHLAENHSADFDPIVYAQIKVTN
What are the official names of this protein?
Transmembrane protein C1orf162.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SFI3_SEGFL
Sequence: KECMVDGTVCYIHNHNDCCGSCLCLNGPIARPWEMMVGNCKCGPKA
What is the function of this protein?
Insecticidal toxin.  It inhibits insect voltage-gated sodium channels (Nav) by partially blocking the channel pore in DUM neurons from the American cockroach, not by acting as a gating modifier.  The inhibition is only partially reversible after prolonged washout.  In vivo, the toxin causes flaccid paralysis followed by death when injected into Heliothis virescens larvae.  It also causes uncoordinated movements followed by full paralysis to sheep blowflies (Lucilia cuprina).  When the toxin is fused to snowdrop lectin, it is orally active against larvae of the tomato moth (Laconobia oleracea), the rice brown planthopper (Nilaparvata lugens), and the peach-potato aphid (Myzus persicae).
What are the official names of this protein?
Mu-segestritoxin-Sf1c, Mu-SGTX-Sf1c, Toxin SFI3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 16 (SFI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_RHOBA
Sequence: MLEELKEEEIVNKIGGRFKLSTLIQKRLVQLNQGSRALVSVDTHDKMSIVLQEIVQDKIFLNMENEIETVDDLDAIVAASEAPELDPSDL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PEPT_GEOKA
Sequence: MKQELIERFIRYAKVNTQSDPNSHTCPSTSGQWELARMLVEELKAIGMEDVTIDDNGYVMATLPANTDKNVPVIGFLAHMDTAPEFTGANVNPQLIDSYDGGDIVLNKEQGIILSPNDFPELAHYKGHTLITTDGTTLLGADDKAGIAEIMTAMNYLIQHPEIKHGKVRVAFTPDEEIGRGPHKFDVAKFGAQFAYTVDGGPLGELEYESFNAAEAKITIKGKNVHPGTAKGKMINSIKIAMEFEQQLPAHEAPEHTEGYEGFYHLLSFQGSVEETKLHYIIRDFDREQFEARKAKMKEIAASLAQKYGNDRITLEINDQYYNMREKIEPVRHIVDIAHEAMTNLGIEPKVKPIRGGTDGSQLSYMGLPTPNLFAGGENFHGRYEYISADNMVKAAEVIVEIIKLFEQKAS
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_STRR6
Sequence: MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PSEPU
Sequence: MNTVRETIAAIATAQGRGGVGIVRLSGPLAAKAGLLITGRTLTPRHAHYGPFRDDEGLVLDEGIALFFPGPNSFTGEDVLELQGHGGPVVLDMLLQRCVQVGCRLARPGEFSERAFLNDKLDLAQAEAIADLIEASSSQAARNALRSLQGEFSRRVHSLTEALIALRIYVEAAIDFPEEEIDFLADGHVLSMLDAVRSELSTVQREAGQGALLRDGMTVVIAGRPNAGKSSLLNQLAGREAAIVTDIAGTTRDILREHIHIDGMPLHVVDTAGLRDTDDHVEKIGVERALKAIGEADRVLLVVDSTAPEASDPFALWPEFLAQRPDPAKVTLIRNKADLSGERVALEQCDDGHVTITLSAKGDDTGLQLLRDHLKGCMGYEQTAESGFSARRRHLDALRQASEHLEHGRAQLTLAGAGELLAEDLRQAQHALGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_LEPBP
Sequence: MFLKKIYIKNFRNHEETQLTFKSRLVFFIGNNGEGKTNLLESISLLSYLKSFRESDQNQLLRWDTSDTFIRAEFESEGNEYLFEYGIEHSQTKRKKLKVNGEEFKKISDYVGYFRSIVMSPPDILIIEDGNVERRRFLDAFISSTNRYYLKQLIEYERLIKQRNAALKKENASDREIGIWDEPIIEHDSEIREIRTKTIQSLAGYFHQNLLQLSSGKDPYFLTYKPNITSKEEHKQKLIDNLRKDKAIGYTSCGNHRDTLPIGFDDKDLSGFGSQGQKRSAVIALKTACFQMIRDTTGEAPVLLIDDIIRELDVKRREYFVNLISECGQAFFTTTDLEGINEYVGNLTVDKEIYIIDSGKVKVFTEI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_SHISS
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLNKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: TGT_RUEPO
Sequence: MSERFSFDLHASDGKARTGVIHTPRGGVRTPAFMPVGTAATVKAMMPESVRATGADILLGNTYHLMLRPTAERIDRLGGLHRFMNWDRPILTDSGGFQVMSLAGLRKLTEKGVTFKSHIDGSKHELTPERSMEIQRLLGSDIVMCFDECPALPADRDRIAESMRLSMRWAERSREAFGDRPGHALFGIMQGGLEQDLREESAQALRSVGFDGYAVGGLAVGEGQAAMFDCLDYAPGFLPEDKPRYLMGVGKPDDIVGAVKRGIDMMDCVLPSRSGRTGQVFTRHGVLNIKNARHMDDPRPLDEACTCPACRNYSRAYLHHVFRSQEIISSMLLTWHNLHYFQEIMQGMREAIAGGTFEAWEAAFHAGRAQGDIEPL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ERPA_LEGPH
Sequence: MANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQINDDDTIVIQQCSDGKSSVKLLVDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ISPE_PELPD
Sequence: MKSLTLKAPAKVNYLLDVIRRRPDGYHDLRMVMQRVNLCDEIAIALTDSPELSVCCGKDGVPDGPGNIAWKAARAMLDLAAGGQGATISIVKNIPVAAGLGGGSSDAATVLMGMNQLLELGLTDQELMRIGVKLGADVPFFIFKKTALAEGIGEQLRAMPPMPALWVLLVNPGVHVSTAWVYKNLRLTSRGELAKLPQFFSTVEDVCSMLSNDLESVTIPAFPVIADIKRAMLAKGALGAMMSGSGPTVFGLFRDREGAEAARAELVEGSGWFAAVAETL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MRJ1_CRYNH
Sequence: MLSFQATVRPLAVSSRLHSPAAHIWRRNAHTAAMSDDSLDQGSSSSYGDSASQPHLGKGKGRQDSLAQSYRFPEKGMNGGPPDPFEVMALDRSATQQEVKQQYYKLALLLHPDSSHPSSSPDHFATLNKAYNLLSKQSSRSAFLKTGYGWDVSTSSGGNQTWSDSLMRAEIARRRNGGAAAWNGASRRYRDSDAGRGAWGGFDGSQGWRPYEDPSKGFSPPTSGPAEERYMSNPRFLAVVGVASAVIAWVHWHRLGYAAETHRDMLDKQNIDASRALAQARYEAATHGHIRREQIRRRVREAEVLKELEKADQGHIAVAGPPTAYPPSHRE
What is the function of this protein?
Mitochondrial co-chaperone required for ubiquinol-cytochrome c oxidoreductase (mitochondrial respiratory chain complex III) activity.
What are the official names of this protein?
Mitochondrial respiration co-chaperone MRJ1, Mitochondrial respiration J-domain protein 1.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PFDB_AERPE
Sequence: MVERLPPEVEAKYTKYLKLRETLSVVMREKATVEAGLAEVESVLKELEGLPEDAELYRLTGFVLVKKSKNEVVEDLNKRKEDLELKLKVLKSQEEHLKKELERIESELRRLLQGGAVGGAKGA
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICR_SALPC
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: GLGA_ANASK
Sequence: MQILFVASEVGPWSKTGGLGDVAGALPQALAERGNEVAVVTPRHGSIDPRAAGLQPVRTALQVRGEPVSLWVKRGPAPVYFVEHPHLFGNRRGLYGEGGRDHGDNAERFAFLTRAALALPGALGLRPRILHLNDWQCGLGPWLLRHEHARDPALAGARTVFTIHNLAYQGLFPKQVLPALGLPWEVFRWEAMEFFDQLSFMKAGLAFADALTTVSPTYAREILTPEGGASLDALLRHRARDLHGILNGIDVHAWDPARDPHLPAHFTAGDLAGKAACKAALQREVGLPVRPEVPVAGLVTRLAEQKGIDLVAAALPALLARDVQVVLLGSGDPAYQETFARAAREHPDRVAARIGFDEGLAHRIEAGADLFLMPSRFEPCGLNQMYSLRYGTVPVVRAVGGLADTVEDFDGVARGTGFRFSEYTPQALLTATRRALDVFRDRRAWRGLVERGMAEDNSWERSAARYEALYRTLAP
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: NDHH_SYNSC
Sequence: MTQLETRTEPMVVNFGPHHPSMHGVLRLVVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMFVPYVSRMDYAAGMFYEAIVVNAPEKLANIPVPKRASYIRVLMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGQRLINNNYFRIGGVAADLPWGWLEKCRDFCDWFGPKIDEYEKLITNNPIFRRRIEGLGRIEKEDAINWSLSGPMLRASGVPWDLRKVDHYECYDDFDWQVAWEKEGDCYARYRVRIEEMRQSLKILRQACDMIPGGPTENLEAKRLNEGKGSDAAGFDFQYVAKKVAPTFKIPNGELYTRLESGKGEIGVFIQGNNDVTPWRFKIRAADSNNLQILPHILKGHKVADIMAILGSIDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SKO1_YEAST
Sequence: MSSEERSRQPSTVSTFDLEPNPFEQSFASSKKALSLPGTISHPSLPKELSRNNSTSTITQHSQRSTHSLNSIPEENGNSTVTDNSNHNDVKKDSPSFLPGQQRPTIISPPILTPGGSKRLPPLLLSPSILYQANSTTNPSQNSHSVSVSNSNPSAIGVSSTSGSLYPNSSSPSGTSLIRQPRNSNVTTSNSGNGFPTNDSQMPGFLLNLSKSGLTPNESNIRTGLTPGILTQSYNYPVLPSINKNTITGSKNVNKSVTVNGSIENHPHVNIMHPTVNGTPLTPGLSSLLNLPSTGVLANPVFKSTPTTNTTDGTVNNSISNSNFSPNTSTKAAVKMDNPAEFNAIEHSAHNHKENENLTTQIENNDQFNNKTRKRKRRMSSTSSTSKASRKNSISRKNSAVTTAPAQKDDVENNKISNNVTLDENEEQERKRKEFLERNRVAASKFRKRKKEYIKKIENDLQFYESEYDDLTQVIGKLCGIIPSSSSNSQFNVNVSTPSSSSPPSTSLIALLESSISRSDYSSAMSVLSNMKQLICETNFYRRGGKNPRDDMDGQEDSFNKDTNVVKSENAGYPSVNSRPIILDKKYSLNSGANISKSNTTTNNVGNSAQNIINSCYSVTNPLVINANSDTHDTNKHDVLSTLPHNN
What is the function of this protein?
Binds to the CRE motif 5'-TGACGTCA-3' and acts as a repressor of transcription of the SUC2 gene and most probably other genes.
What are the official names of this protein?
CRE-binding bZIP protein SKO1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.