PharMolix/UniProtQA huggingface dataset:
Protein: DHKC_DICDI
Sequence: MIVEVELGFLLSTLFFTIISIILFYFFINNKNNLIDQCQEVTKLNNKDNKIVNNNNNNYNNNNFNKIEEINDDKNKEIIKLINNSNNKNLKIKIQEIDSGNNNNNNNNNNNNNNNNLNKNSNEIFRNFKIFSGSLLVIDQDLNIISSSESVRDIFSNINDINGVNQQVIGSLQNYSFINLVHQKDKDRVSTFLKLKFKNNNNIKHQQFSEDIINEKDELKEIQIEDNKELIIINNNNNNNNDNVLKFGNNNSNNSSIILFQGVYHLNNTDLSKPFNLQVSILPFISENYIVLSLKDLSPPPLRLLLNKTSSALSPRSLSSSSSSSPSSSNNNGNTNNSGSLSPRSSNSNGSAVSPRNVSSNSMSPRGQNSDRSISSPRGSSSSSSSSSNELAISPRNSNGTISSPRTSNLSIESVLNNKSIDMISHLSHELRTPIHSVIASIQLFRSTILTVTQNEYLSIIDTSANTLLELVSNVLDYKRIRSGKLTLNNVDFNLCHVIEDVCAMVSPQAQAKSLQIASFIFIHCPLSFYGDPIRLRQVLLNLIGNGLKYTNKGQVCISVEPEQVNEHCMYLHFQVKDSGIGIKEENMSKLFAGFSQVNNGGTTQEALGSGLGLAISKDLVELMGGKIWCSSNATQNNGEAGCTFHFVIPLETNPKQLPCPIQNFNGLSVLVVDKNPYIQTVLCQYLEGWNCQVIKSSDIKEASNKLKDLRREQIEVVMIDIDNIDFRDFIQFKDAFNRLEFGRIGLITMSSDRSMVNEMGFGTSKLTKPFRQSHLVACLLASMPEHSSSTTNCFSNIVGMNSNINNNNNINNNSNNNNNNMQTHNSNSVYGNGNYGNCTPFSNNNNRIHMMSSGDKPSINNRRMSISLGKIPTFNSGGSNSPRSKKLFEEVLQQQQLQQQLQQQLQQQQQLQQQQQQQQQQQQQQQQQLQQQQQQLNTIDDDSNNYCNTTGTMDSIDEINKNNYSDSESDELNDDQAPIIAPVQQLSFGRVTRRHSIDIIMFENSRELSELRNLEDSTRYLSPRSMNNNNGNNDNGINGGSGNSLFGSSIKEEIGGTSDTSSLAQSPNSLSPRAPTKIMILDDNPVSLKLMQRILESRGFECYPFDCSEKAVAQLDQVNPAIIFMDCEMPKMNGFECTQLIRKREQESLCLLKDRKIIIALTAHINPEIQVKCFDAGMNDFISKPFKPQCLELILRKWEDCISNNQLNYNNSLINNQTTIQEQV
What is the function of this protein?
Acts in a signal transduction pathway that regulates the slug versus culmination choice.  Believed to be the first component of a phosphorelay that couples the sensing of ammonia to the modulation of PKA activity and hence activates culmination and spore germination.  Ammonium transporters amtA and amtC are thought to respectively activate and inhibit dhkC phosphorelay.  This protein probably undergoes an ATP-dependent autophosphorylation at conserved His residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain.
What are the official names of this protein?
Hybrid signal transduction histidine kinase C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CIH1_COLLN
Sequence: MQTSFVALLAVAASLASALPHGGNSYEASLPEPTNLPEPTKLPEPVEGPYKPKPPILPEPIKDNYKPKTPILPEHVEGPYKPKLPEPTTGDPKNNTLPVPTCVDGKIKTHKVKSGESLTTIAEKYDTGICNIAKLNNLADPNFVDLNQDLQIPTDACEKDNTSCIKPDGTATCVKDGKKDGKDIYSVVSGDTLTSIAQALQITLQSLKDANPGVVPEHLNVGQKLNVPVC
What is the function of this protein?
May have roles in host-pathogen interaction, including establishment and maintenance of biotrophy, prevention of host recognition of the fungus and a barrier to host defense molecules.
What are the official names of this protein?
Intracellular hyphae protein 1.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Cell wall and surrounding interfacial matrix.
Protein: GCH1_SYNY3
Sequence: MTIASSHSINNGMNTGKLVNQLSSLPDRNTHNGQEVKYHPENVELNKEKMMDAVRVMLESVGEDPEREGLLKTPKRVAEAMQFLTQGYDQSLEKLVNGAIFDEGHNEMVLVRDIDFFSLCEHHMLPFMGKAHLAYIPNQKVVGLSKLARIVEMFSRRLQVQERLTRQIAEAVQEILDPQGVAVVMEATHMCMVMRGVQKPGSWTVTSAMIGSFQNEQKTREEFLNLIRHQPNFY
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: 029L_FRG3G
Sequence: MRRMRSGFKHCAIPIDICRWEYILSPLILQDLQGPQQGGSVAVDVTVRCSVRFVHLPHYGGFNHGTVQRRVDPDDCRILRQLHIVLSLRLCLIDRDRL
What are the official names of this protein?
Uncharacterized protein 029L.
Protein: YA037_YEAST
Sequence: MSISFPKMQHLIVMTTIGDKKVNNNIILFL
What are the official names of this protein?
Putative uncharacterized protein YAL037C-A.
Protein: CAEA_CONTS
Sequence: DGCPPHPVPGMHPCMCTNTC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like ts14a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3921_BACCR
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENDSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGPYLELYKLEVLPTFQKQGFGQMLVNHAKQMQFPIKTIARIHSAGFWDKLNFNPVSVTDGDFYIWHPETNLNAVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BC_3921.
Protein: DAPA_BUCAT
Sequence: MFKGSIVALITPMDEKGQICRISLEKLINYHVASKTEAIVSIGTTGESATLSQEEHINIVMLTLELADGRIPVIAGTGANATTEAISLTKRFEKSGVAGCLSVTPYYNRPTQEGLYQHFKAISENTELPQILYNVPSRTGCDLLPETVAKLSHFNNIIGIKEATGDLSRIHKIKELVKTNFLLISGDDATALDFMQLGGQGVISVTANIAAKEMMEICSYALKGDFINARSINKRLMLLHEALFIEPNPIPVKWLAKKIGLIKSDTLRLPMTPVLDSTRFQLEKAIQYANLKIS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORED_MOUSE
Sequence: MAGWAGFELSALNPLRTLWLALAAAFLFALLLQLAPARLLPSCALFQDLLRYGKTKQSGSRRPAVCRAFDVPKRYFSHFYVISVVWNGSLLWLLSQSLFLGAPFPNWLSALLRTLGATQFQALEMESKASRMPAAELALSAFLVLVFLWVHSLRRLFECFYVSVFSNAAIHVVQYCFGLVYYVLVGLTVLSQVPMDDKNVYVLGKNLLIQARWFHILGMVMFFWSSAHQYKCHVILSNLRRNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNLTWWLVVTYVFSSQALSAFFNHKFYRSTFVSYPKHRKAFLPFLF
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol (PubMed:20637498).  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation (PubMed:20637498).  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (PubMed:20637498).  Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT) (By similarity).
What are the official names of this protein?
Polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 3, Steroid 5-alpha-reductase 2-like, Steroid 5-alpha-reductase 3, S5AR 3, SR type 3.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PCKA_COXB1
Sequence: MEQIAARVTYINLSPDELIQHAVKNGEGVLSSTGALAVTTGKRTGRSPKDRFIVKDEQTADQVAWGNINQPVEQRTFDQLWERALRYLSERAVYISHLQVGADDNYFLPLKVVTEFAWHNLFACDLFIRPSGDHANGKPSWVILSAPGLKTDPERDGVNSDGAVMINLSQRRVLFVGMPYAGEMKKAMFSVLNYLLPPHDVLPMHCAANAGQSGDVALFFGLSGTGKTTLSADPHRFLIGDDEHGWSATSVFNFEGGCYAKCIDLSQEREPMIWNAIRHGAIMENVVLDENGVPDYADARLTQNSRAAYPREHIPLRVENNRGRPPDAVLFLTCDLDGVLPPVALLTKEQAAYYFLSGYTALVGSTEVGSVKGVTSTFSTCFGAPFFPRPPTVYAELLMKRIEATGCQVYLVNTGWTGGAYGEGGERFSIPTTRAIVNAVLSGKLKEGPTEVLSGFNLTIPKSALGVDDHLLNPRKTWEDVSAYDARAQRLIQKFRENFEKFKVPAAIREAGPSDVH
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUM_MACFA
Sequence: MLCCMRRTKQVEKNDEDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDAQAAEAEANKKDEAPVADGVEKKGEGTTATEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA
What is the function of this protein?
This protein is associated with nerve growth.  It is a major component of the motile 'growth cones' that form the tips of elongating axons.  Plays a role in axonal and dendritic filopodia induction (By similarity).
What are the official names of this protein?
Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43.
What is the protein family that this protein belongs to?
Belongs to the neuromodulin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Protein: GUN9_ARATH
Sequence: MTSLFFFVLLFSSLLISNGDANPNYKEALSKSLLFFQGQRSGPLPRGQQISWRASSGLSDGSAAHVDLTGGYYDAGDNVKFNLPMAFTTTMLSWSALEYGKRMGPELENARVNIRWATDYLLKCARATPGKLYVGVGDPNVDHKCWERPEDMDTPRTVYSVSASNPGSDVAAETAAALAAASMVFRKVDSKYSRLLLATAKDVMQFAIQYQGAYSDSLSSSVCPFYCSYSGYKDELMWGASWLLRATNNPYYANFIKSLGGGDQPDIFSWDNKYAGAYVLLSRRALLNKDSNFEQYKQAAENFICKILPDSPSSSTQYTQGGLMYKLPQSNLQYVTSITFLLTTYAKYMKATKHTFNCGSSVIVPNALISLSKRQVDYILGDNPIKMSYMVGFSSNFPKRIHHRASSLPSHALRSQSLGCNGGFQSFYTQNPNPNILTGAIVGGPNQNDGYPDQRDDYSHAEPATYINAAFVGPLAYFAAGRST
What are the official names of this protein?
Endoglucanase 9, Cellulase 3, AtCEL3, Endo-1,4-beta glucanase 9.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: DHB3_HUMAN
Sequence: MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR
What is the function of this protein?
Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids (PubMed:8075637, PubMed:16216911, PubMed:27927697, PubMed:26545797).  Favors the reduction of androstenedione to testosterone (PubMed:16216911, PubMed:27927697, PubMed:26545797).  Testosterone is the key androgen driving male development and function (PubMed:8075637).  Uses NADPH while the two other EDH17B enzymes use NADH (PubMed:26545797, PubMed:8075637, PubMed:16216911).  Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17 (PubMed:16216911).  Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms (PubMed:16216911, PubMed:27927697).
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase type 3, 17-beta-HSD 3, Estradiol 17-beta-dehydrogenase 2, Short chain dehydrogenase/reductase family 12C member 2, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: PUFX_RHOCA
Sequence: MSMFDKPFDYENGSKFEMGIWIGRQMAYGAFLGSIPFLLGLGLVLGSYGLGLMLPERAHQAPSPYTTEVVVQHATEVV
What is the function of this protein?
Associated with the reaction center - light-harvesting complex I.  May play a critical role in facilitating the interaction between this complex and other components required for light-driven cyclic electron transfer.
What are the official names of this protein?
Intrinsic membrane protein PufX, Protein C2397.
What is the protein family that this protein belongs to?
Belongs to the PufX family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PDD2L_CHICK
Sequence: MAAAAPPVLRGLRDAAMVGPCRGGGEPPGWATNKLGGRADALPSVRPGCPRCGACGAALAHLVQVYCPLGASPFHRLANVFACAESACWGRPQSWKVLRSQSLEARGQDALGCGSKQKEECNFSAKDWCAEADDWGGCDGTESSTCALQMLGLNAGMSSSASEEAQCVSQLQELHLSEAADVSGSLNTDLLLREEMVMATSAPVFHSYYISVVDEADYAGFLDTDHANKLLKEYQQREGVDLEHLMSESFAGEDSNEKYEKTKVRSGDHTFHKFMKRISVCPEQILRYSWGGQPLFITCPPANFDNSIPACSNCGSNRVFEFQLMPALVSMLWGDADLSVEFGTVIVYTCERSCWPTNQQTPLEEFIFVQEDPDQKLFK
What are the official names of this protein?
Programmed cell death protein 2-like.
Protein: SWT6A_ORYSJ
Sequence: MISPDAARNVVGIIGNVISFGLFLAPVPTFWRICKRKDVEEFKADPYLATLLNCMLWVFYGIPVVHPNSILVVTINGIGLLVEGTYLLIFFLYSPNKKRLRMCAVLGVELVFMLAVILGVLLGAHTHEKRSMIVGILCVFFGSIMYFSPLTIMGKVIKTKSVEYMPFFLSLVCFLNGVCWTAYALIRFDIYVTIPNGLGALFGAIQLILYACYYRTTPKKTKAAKDVEMPSVVVSGTGAAAAAGGGNTGGGSVSVTVER
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET6a, OsSWEET6a.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LAMB_SALHS
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQVTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVNQQNDWESTDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENIDLGFGKLSLAATRSTEAGGSYTFSSQNIYDEVKDTANDVFDVRLAGLQTNPDGVLELGVDYGRANTTDGYKLADGASKDGWMFTAEHTQSMLKGYNKFVVQYATDAMTTQGKGQARGSDGSSSFTEELPDGTKINYANKVINNNGNMWRILDHGAISLGDKWDLMYVGMYQNIDWDNNLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNVKSQQTGDRNNQYKITLAQQWQAGDSIWSRPAIRIFATYAKWDEKWGYIKDGDNISRYAAATNSGISTNSRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: S247A_DANRE
Sequence: MHFADFLAGSFGGACGVAVGYPLDTVKVRIQTQKQFTGIWQCIVLTIRKEGVHGFFKGMFLPITTISMTSSVVFGTYRNCLQALSYIRKAENTKLDVFMSGLAGGVAQVSVMSPGDIVKVRLQCQTESRHSVNPKYSVKPKYSGPIHCLLSICREQGLSGLYRGALPLALRDGPSFATYFLTYHTLCARLTPDGQKEPEWTVVLLSGGVAGMSGWAVGTPMDVIKARLQMDGVRGQRRYRGLLHCLTVTTRTEGLGVFFRSLGINCLRAFPVNMVVFAVYEVSVRVLRSAPLVS
What are the official names of this protein?
Solute carrier family 25 member 47-A, Hepatocellular carcinoma down-regulated mitochondrial carrier homolog A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRH_METST
Sequence: MRIVITIGGSILLKEYDNKKFEDYAKIIRQINEDHEIFIVVGGGRPARDYISVVRDMGETESICDEIGIQVTRINARLLQLALKDVSYPAIPVNFQQALEFSATGKIVVMGGTEPAHSTDAVGSILAEYVGADLVINATSVDGLYDKDPNKYNDAQMFSEVSADKLMEIVSDNDTKAGTYEFIDKTAIQIIKRSKIKTVIVNGNTPENVKTAITQPIGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_BRUME
Sequence: MPPYRSRTTTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIESAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKVVWEDSVKKLDLVDAMVAAADDHYTDEQVKAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVDLARRYYEQDDESVLPRSIATFSAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMADIDRLSRRVPVLCKVAPAVSSVHMEDVHHAGGIMGILGQLDNAGLLTTSIPTVHSETLAKALDHWDVTRTNSEMVHKFYSAAPGGVPTQVAFSQERRFDKVDTDREKGVIHSKEHAFSQDGGLAVLYGNLAEDGCIVKTAGVDDSILKFSGPARIFESQDSAVLGILNGKIKPGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGSSGLSIGHVSPEAAEGGTIGLVREGDIIDIDIPNRKIHLAVDDATLAERRAEQDAAGWKPAEERKRKISTALKAYAAMATSAARGAVRKLPD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: LPXB_BLOFL
Sequence: MINNRSVIIGIVVGENSGDILGVGLIRSLKKCFKKVQFFGIGGFRMRSENMECWYDISELSIMGITGVIFRLPKLLNMRRELIKRFLKLKLNIFIGIDFPDFNISLEKRLKKYGITTIHYVSPSIWAWRSNRVFALKEATHNVLLLFPFEKSIYARCGIPNQFIGHPLADEIPLYPNKIALRQKFDIPSNRCCLAILPGSRPKEIQILTKIFMHCAKLLQDTIPNLEILIPLHDTDLINQFVTLTSFISVKFRVLHTLTAWEVMAAADAALLTSGTATLECMLAKCPMVVAYRMNPVIFMLIRHLIKVKWISLPNLLAGKPIVQEFIQKKCDPQRLASSLFYLLNYNQEQRTTLQQEFYHLHRSIKLHANDQATRLILKYINLL
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: METK2_HORVU
Sequence: MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRDIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGIMFGYATDETPELMPLTHMLATKLGARLTEVRKNGTCAWLRPDGKTQVTIEYLNEGGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPGKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGKRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBS_TOBAC
Sequence: MAQTMLLTANAKVDLRSKESLVERLKPKPLSSFFLPSLPLKYPSASASASSHFTSTTVALFKSKAKAPAKKVVPKPKEKVEDGIFGTSGGIGFTKQNELFVGRVAMIGFAASLLGEAITGKGILAQLNLETGIPIYEAEPLLLFFILFNLLGAIGALEDRGKFIDDPAPPTGLDKAVIPPGKGFKSALGLSEGGPLFEFTKANELFVGRLAQLGIAFSIIGEIITGKGALAQLNFETGVPINEIEPLLLFNIVFFFVAAINPGTGKFVTDEEEE
What is the function of this protein?
Seems to be involved in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.
What are the official names of this protein?
Photosystem II 22 kDa protein, chloroplastic, CP22.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QTRT2_XENTR
Sequence: MKLSISKVANGARLGVISNIGRNGDKTLEVPGCLLYTKTGSPPHLTHDTLQTIEGVPAVTHITLSTLAEHQEVLEEYKEGIGKFAGMPDAVLYCSTHDPVSPCPTGYNTNKAVSLWGAGGRIEMTAQKFISAQRVLRPDWFQCLSDGEVTPGGNSRKRVKKSVDRTLAFLDECLQLLSGHEDLKPCVLIGAVEGGDLLEERLRSARETAKRPVGGFLLDGFHGGSAEKELSLISAVTAALPEDKPRFIHGMGRPDEVLECVQRGVDLFDSCFPYRVTERGCALIFSHCYRPDPETAVLEKSETSGAERNGDVGAESEEPDADRAEMTSFEICLKEKRFREDFRPLLEGCSCYCCRNHSRAYVHHLLAAKELLAGILLMIHNFQHYFRFFGSIRAALRDGEINALAELIRKQSS
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=May associate with the mitochondrion outer membrane.
Protein: ACT5_DROME
Sequence: MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
What is the function of this protein?
Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin-87E.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: INT9_XENLA
Sequence: MKLYCLSGHPTLPCNILKFKSSTIMLDCGLDMTSTLSFLPLPLVHSTRLSKLPGWVTKDGNNQFEKELKECSGRVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITERTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQSATVWKHKDVQRLLPAPLKDAVEVFTWKKCYSMQEVNAALSKIQLVGYSQKIELFGVVQVTPLSSGYALGSSNWVIQSHYEKVSYVSGSSLLTTHPQPMDQTSLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTIRSGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQNKVYLPEPPFPHAELIQSNKLKHYPNIHGDFSNDFKQPCVVFTGHPTLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVTKLLKEVQPLHVVCPEQYTQPPATQSHRSDLMIDCQPPPMSYHRAEVLTLPFKRRYEKIEIMPELAQSLVPFEMKPGVSLATVSAVLHSKDNKHVLQPPPKPVAPPGSKKRKRPAEESPETPPFKPLLSGSIPVEQFVQTLEKNGFSDVKIEDTAKGHIVHLQEAETLIQFEEDSTHIICEHDERLRVRLRDLVLKFLQKF
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 9, Int9.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUP50_DROME
Sequence: MAGKRQATSNLNHENWDLEEEPEERGTFRTATEEELKTRVIKKARRKIAGGSSAAEEDGAEEKTAEPKSVFSGFSGFGKPAASPAAGSPFSFLANVTAPATTSSSEPKKSAFSFGFSSSSSSADRPVSTSICGTASTSSTAPSPLPAKESTSTVDGAKPTTSIFGNISAAKKESSEAKTSSSSTSLTSTMETSEYRESVADLNRSVIKFLQDQMGKSPYCILTPVFKNYDEHLKDLQDEESARTNSTKSKTAQARSQEPVAKVSRASSPPKAATTFTFGKPSAPIGASVSPLAKKPNCTITSGGTTTTTATPLVSFGSTASFTAPVPSSSSIFSLTAKPTGEAKSDDTPKSSIFSFGAKDTTTKKDEPNFSAPKTNGFSFGLKSNNDDKPSTSLFAGFGKAPGGAGDGAKGFSFTNSATPFSLGNIHPPAAAAAPAEEEKEEDTPPKVEFKQVVEDDAIYSKRCKVFIKKDKDFGDRGVGTLYLKPVKDSEKIQLLVRADTNLGNILVNLILSKGIPCQRMGKNNVLMVCVPTPEDSKATSLLLRVKTGDEADDLLEKIKEHIK
What is the function of this protein?
Component of the nuclear pore complex that has a direct role in nuclear protein import (By similarity).  Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (By similarity).  Binds to transcriptionally active chromatin sites when located in the nucleoplasm and is involved in transcriptional activation (PubMed:20144760).
What are the official names of this protein?
Nuclear pore complex protein Nup50, 50 kDa nucleoporin.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus envelope. Chromosome. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Associates with chromatin (PubMed:20144760).