PharMolix/UniProtQA huggingface dataset:
Protein: TSN1_SCHPO
Sequence: MNKSIFIQLQDQIDKEHSIREKLTAEVDLLDEKLRVLQLLLANCEQNLENQEEILEALEIIKSKTRGLAELASNFPYYKYNGVWDRSIQKVVYLYLLASWTGRLDKSLRPTYSLLSLSEVGQILQVPVFPEESTFHLSIEQYLHAVLSLCSELARQSVNSVISGNYHIPFEALNTIQKVHSSFQVLSLKNDSLRRHFDGLKYDLKRSEDVVYDLRIHKLV
What is the function of this protein?
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations.  Selectively binds single-stranded d(GT)n and d(GTT)n microsatellite repeats.  Has much higher affinities for the homologous RNA sequences (GU)n and (GUU)n.  Does not bind double-stranded DNA.  Has a role in meiosis.
What are the official names of this protein?
Translin-1, Meiotically up-regulated gene 90 protein, Translin homolog.
What is the protein family that this protein belongs to?
Belongs to the translin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECA_PROVU
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKDGEEVVGSETRVKVVKNKVAAPFKQAEFQILYGEGINIHGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANACNFLKENSLVKETKNFNGC
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PROMH
Sequence: MLQPKRTKFRKVHKGRNRGLAIGTDVSFGTYGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEEVAREAFQLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: IL3RA_MOUSE
Sequence: MAANLWLILGLLASHSSDLAAVREAPPTAVTTPIQNLHIDPAHYTLSWDPAPGADITTGAFCRKGRDIFVWADPGLARCSFQSLSLCHVTNFTVFLGKDRAVAGSIQFPPDDDGDHEAAAQDLRCWVHEGQLSCQWERGPKATGDVHYRMFWRDVRLGPAHNRECPHYHSLDVNTAGPAPHGGHEGCTLDLDTVLGSTPNSPDLVPQVTITVNGSGRAGPVPCMDNTVDLQRAEVLAPPTLTVECNGSEAHARWVARNRFHHGLLGYTLQVNQSSRSEPQEYNVSIPHFWVPNAGAISFRVKSRSEVYPRKLSSWSEAWGLVCPPEVMPVKTALVTSVATVLGAGLVAAGLLLWWRKSLLYRLCPPIPRLRLPLAGEMVVWEPALEDCEVTPVTDA
What is the function of this protein?
Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (By similarity).  Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation (PubMed:10477686).  Activation of JAK2 leads to STAT5-mediated transcriptional program (PubMed:10376805).
What are the official names of this protein?
Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, Interleukin-3 receptor class II alpha chain.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=Expressed on the cell surface. SUBCELLULAR LOCATION: [Isoform 2]: Endomembrane system; Single-pass type I membrane protein. Note=Mostly distributed inside the cells, except in the nuclei and is not transported to the cell surface.
Protein: FPG_BRUA2
Sequence: MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RIP1_MYCBP
Sequence: MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWSTRRGETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGETGCVAQEVSQGKLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAAAVRKSHGSVPIVVERDGTAIVTYVDIESTQRWIPNGQGGELQPATVGAIGVGAARVGPVRYGVFSAMPATFAFTGDLTVEVGKALAALPTKVGALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLILATINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATYVVLVLVVGYMLLTVTADLVNPIRLFQ
What is the function of this protein?
Regulated intramembrane proteolysis (RIP) occurs when an extracytoplasmic signal (possibly oxidative stress) triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein (includes anti-sigma factors RskA, RslA, RsmA, and PbpB in M. tuberculosis) is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, this entry), while cytoplasmic proteases finish degrading the regulatory protein, liberating the effector protein (ECF sigma factors SigK, SigL and SigM) (Probable).
What are the official names of this protein?
Zinc metalloprotease Rip1, Regulator of sigma KLM proteases, S2P endopeptidase, Site-2-type intramembrane protease, site-2 protease Rip1, S2P protease Rip1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_BORPA
Sequence: MSMSDPIADMLTRIRNAQQVDKTTVTMPASKLKVAIATVLKDEGYIDGYSVKGTQAKPELEITLKYYAGRPVIERIERVSRPGLRIYKGRTSIPQVMNGLGVAIVSTSRGVMTDRKARANGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ATG17_SCLS1
Sequence: MASPTNAPGSQSQTSVSSANHPDPIIHGREILETLVSHLLASKRSLSSISTVWRANEIVTSAKTALEESVILNARTGFLQSGINEQMKVLMKVRNSIECVYNDGQKDFKNVLHTLDAANARLESTMDVLRSTMVDAAFRPAGEEPRSLLDFVDEQGVEGMRDGLKELIRESKETQKEFDTSLLSFDDDLRSLRSGFKNTKVSPPSYSPIPSHLATLEGHAQEMAALLSSLSSHFDLCLNAIRHTEGGYAAVRNAASNPPPGAEPVSVSGVMNTSHDDINEEPLTEHEREEMLFVLEKDAAEVEDVVMELRDRQNEMEIKHDAILDHVSHLTEQFKQTTSIYKILEGVYERLPGYIIAGQDFRARWEDTKAQICGQMDDLEGMRLFYENYLSSYDGLILEVRRRKVAEEKAKTIAKKAMEQISKIYDADMKERHDFKHDVGDYLPVDLYPGINAAAPRWEFRLMEDEEAVNSSPSLERELVEVSSKRDGEAQG
What is the function of this protein?
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation.  Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles.  Plays particularly a role in pexophagy and nucleophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 17.
What is the protein family that this protein belongs to?
Belongs to the ATG17 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: APT_NOSP7
Sequence: MDLKSLVRDIPDFPKPGILFRDITTLLRDPEGLRYTIDFLTQKCKEAEIKPDYVIGIESRGFIFGSPLAYQLGAGFIPIRKRGKLPAAVHSIEYDLEYGTDCLEVHQDALRHSSRVLIVDDLIATGGTASATAKLVQKIGCELVGFGFIIELRDLEGRKYLPDVPIISLIEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO12_HALWD
Sequence: MSYKCSRCKRDVELEEYGGVRCPFCGHRVLLKERAPEIKEVPVE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG155_CAMPM
Sequence: MNSLSIFFIVVATAAVCLLFIQGYSIYENYGNIKEFNATHAALEYSKSIGGTPALDRRVQDVNDTISDVKQKWRCVAYPGNGFVSASIFGFQAEVGPNNTRSIRKFNTMAQCIDFTFSDVINIDIYNPCVAPNINNVECQFLKSVL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein OPG155, Protein CMLV147.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG155 protein family.
Protein: ATPA_BURM9
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVLDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHADLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLYA_EHRRG
Sequence: MVRYISDYDLQDVDTEVFKCITDESNRQNSQLQLIASENFVSKAVLQAQGSIFTNKYAEGYPGKRYYCGCHFADIIENIAIERLCKLFGCKFANVQPHSGSQANQGVFAALLKPGDTVIGMSLDCGGHLTHGSAPSISGKWFNAVQYQVDRDTGMIDMDAIEKLALSHNPSLIIAGSSSYPRTIDFKRFREIADKVGAYLLADIAHYAGLVAAGEFPSPIEYAHVITSTTHKTLRGPRGAVIMTNHEDIYKKIQSSIFPGMQGGPLMHVIAARAVAFGEALKPEFKDYAKQIIKNSKTLVKVFQERGLNVVTGGTDSHMVVVDLRPKSVTGKDAVLALERLGIICNKNAIPFDPEKPFVTSGLRFGSAAETSRGLQEPEFEKIGHMVCDVIDSLKTTDDVRLSIEQDVIRRVKELTDTFKV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_MARN8
Sequence: MAKSDVIEMEGVIVDTLPNTMFRVELSNGHVVTAHISGKMRKNYIRILTGDKVKVELTPYDLSKGRIVYRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_THEMA
Sequence: MKLRYLNILKEKLGREPTFVELQAFSVMWSEHCGYSHTKKYIRRLPKTGFEGNAGVVNLDDYYSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMGARPTAIFDSLHMSRIIDGIIEGIADYGNSIGVPTVGGELRISSLYAHNPLVNVLAAGVVRNDMLVDSKASRPGQVIVIFGGATGRDGIHGASFASEDLTGDKATKLSIQVGDPFAEKMLIEAFLEMVEEGLVEGAQDLGAGGVLSATSELVAKGNLGAIVHLDRVPLREPDMEPWEILISESQERMAVVTSPQKASRILEIARKHLLFGDVVAEVIEEPVYRVMYRNDLVMEVPVQLLANAPEEDIVEYTPGKIPEFKRVEFEEVNAREVFEQYDHMVGTDTVVPPGFGAAVMRIKRDGGYSLVTHSRADLALQDTYWGTLIAVLESVRKTLSVGAEPLAITNCVNYGDPDVDPVGLSAMMTALKNACEFSGVPVASGNASLYNTYQGKPIPPTLVVGMLGKVNPQKVAKPKPSKVFAVGWNDFELEREKELWRAIRKLSEEGAFILSSSQLLTRTHVETFREYGLKIEVKLPEVRPAHQMVLVFSERTPVVDVPVKEIGTLSR
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_STAAR
Sequence: MKHQETTSQQHNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASSAAVYTLNQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGIDDAQQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHINDANFATPGAFNEAILTTDTCTKHIAVSLNIDGKTITIGGSAKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTNDMVLVMANQQVEHQILNQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKSAIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDLSYDYVRINASYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_COCIM
Sequence: MERMLLLSPPSLAARPERLNTILSSHSRYATDLQMLDRVAAGLVSLPQSTYDIVMLLTDVDGLGTGSTSAMGRGVIQSVVRALRPGGKFKRENGTFTSTECPDNTELMLAGLVFDDTGGLLKPDFGPENIVPLKLGKRKPVHSVSSNGTGTSGPHVNMQLSTGSMLKGQTTTIKGVGFVDFTDDPSLSEADIYSGQTDDELIDEETLLDGEDMGRPIIQPPECRPKAGKRRRACKDCTCGLAERLREEDKAARAKADATLETMKLAPKELAEVDFTVQGKLGSCGNCALGDAFRCDGCPYIGLPPFKPGEEVRLLSNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RIMP_LACLS
Sequence: MNDVVKIVEDFIKPHIPKPFELFAVEWEKFGGDMMLSILVDKEGGIEIDETAELSELISPLLDTISPDPFPTEGYLLEVASPGAERPLRKAEHFAGAVGEYIFVKLYQKINNEKEFTGDLVSFDGENLVVDVLDKTRHKNIEIPLSAVAKAQTMVKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYY_PIG
Sequence: YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
What is the function of this protein?
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
What are the official names of this protein?
Peptide YY, PYY, Peptide tyrosine tyrosine.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_BURCJ
Sequence: MDIKRTVLWVIFFMSAVMLYDNWQRDHGRPSMFFPSATHTAPAAAGGASGTGATTAGDVPAAAAGAAPSTTAPAAQAQLVKFSTDVYDGEIDTRGGTLAKLTLKKQGDGKQPDLYITLFDHTAGHTYLARTGLLGGDFPNHNDVYTQLNPGSTSLTGDQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIDNVGTAPVTPTVYMELVRDNTAVETPMFSHTFLGPAVYTDAKHFQKIDFSDLDKNKANFEKSADNGWVAMVQHYFASAWIPQQGAKRDIYAEKIDPALYRVGVKQPVAAIAPGQSADVQARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYVGNWGWAIVLLTVLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPFFILPVLMAVSMFVQTSLNPTPPDPVQAKMMKFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRKLGGVKKKPA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSA3_DEBHA
Sequence: MAAAQVKNEKIGNPKSNRRRRKKRRTEDFSSDSESSSSSSSDESMDDAAEEPKPIKETKSINIDDIDIDSDKETDVNSQEKQNSLRPEPLSNETHEKLSNIKLTTSKLTSVGGSSKNSNIDINQVKKTLAKDKDQLNNEYLMLMASSFSNDLDELRKKPDFTDKSLVLLAKTLQSGSNMFDEETLNAILEQ
What is the function of this protein?
Required for efficient biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome assembly protein 3.
What is the protein family that this protein belongs to?
Belongs to the RSA3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: VP2_SVM93
Sequence: MSWLVGALQTFGSLADVAGTVSNIVYQQRQAAQLEKQNELMETWMNKQEALQKSQMELTRDLSINGPAARVQSALDAGFDEVSARRIAGSGERVIWGNLDRPIMHAGTMDSIRQTKHLDSLSHSLATFKNGTPFGKPAPPTTKFGKPQATTAQINIGHNPGSSSV
What is the function of this protein?
May be a minor structural protein present in one or two copies per virion.  May play a role in RNA genome packaging (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the sapovirus VP2 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: LIP1_STAA8
Sequence: MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRIKEAPSLNKLDQTSQREIVNETEIEKVQPQQNNQANDKITNYNFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNHDNMISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTKATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKLTDTKQA
What are the official names of this protein?
Lipase 1, Glycerol ester hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: COABC_THEKO
Sequence: MLHHVKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSENATKIIHPYAMEFATGNPVVTEITGFIEHVELAGEHENKADLVLVCPATANTISKIACGIDDTPVTTVVTTAFAHTPIMIAPAMHSTMYDHPIVKENIEKLKKLGVEFIEPRFEEGKAKVASIEEIVYRVIRKLHPKSLEGKRVLVTAGATREYIDPIRYITNASSGKMGVAIAEEAEFRGAEVTLIRTKSSVPSFVENQIEVETVEEMLEAIESELKGKKYDVVVLAAAVSDFRVKNKADVKIKSGQPLVLELEPTPKIIDRVKELQPGVFLVGFKAETGLSEEELISAARKQIERAGSDLVVANTLKAFGSEENEVVLVGRDFAKKLPRMTKRELAERLWDEIEKML
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: CYSC_SHEDO
Sequence: MTDIVWHQHSIDQAARGAQKSQNPVLLWFTGLSGAGKSTLAGALERALFDAGFHTYLLDGDNVRHGLCKDLGFSLSDRDENLRRVGEVAKLMVDAGLVVLSAFISPTRAERDRVRALFPEGRFIEVHVSTPLSVCEARDPKGLYVKARSGEIKEFTGISSPYEAPTAAELTIDTSRGDLATQVQAMLAYLTAIEVIDANKLSALA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: NCB2_YEAST
Sequence: MAGDSDNVSLPKATVQKMISEILDQDLMFTKDAREIIINSGIEFIMILSSMASEMADNEAKKTIAPEHVIKALEELEYNEFIPFLEEILLNFKGSQKVKETRDSKFKKSGLSEEELLRQQEELFRQSRSRLHHNSVSDPVKSEDSS
What is the function of this protein?
Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex.  The NC2 complex may also mediate transcriptional activation from TATA-driven promoters through association with SPT15/TBP.
What are the official names of this protein?
Negative cofactor 2 complex subunit beta, NC2 complex subunit beta, Transcriptional repressor YDR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUI1_PYRAB
Sequence: MPRIVNPLDEMLFKEVLKEQQRIRVYTERARYGKIKTIIEGIDEKEFDLEEIAKKLKAKLACGGTAKNGRIELQGDHRDRIKKLLAELGFSEDLIEVE
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.