PharMolix/UniProtQA huggingface dataset:
Protein: SYK_STAHJ
Sequence: MSEEMNDQMQVRRQKLQELIDLGIDPFGKRFERSATASELKSQWDEFSKEELHDKEDESHVSIAGRLMTKRGKGKAGFAHVQDLTGQIQIYVRKDQIGEEDFDNLWKGADLGDIVGIEGVMFKTNTGELSVKAKTFTLLSKALRPLPDKFHGLQDIEQRYRQRYLDLITNQDSTQTFINRSKIIQEMRNYLNKQGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIAQEVFGSAKVQYNEEEIDLESAWTRLHIVDAVKEATGVDFYQIKSDEEAIAAAKEHGIEITNNMKYGHILNEFFEQKVEETLIQPTFIYGHPIEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P66A_MOUSE
Sequence: MSEEACRTRSQKRTLEPDLTEDDVENKKMKMEKGSSELTVDGDSRVMPEPSAGSAQGLLRTTEAMGTGSGEGLLGDGPVDMRTSHSDMKSEKRPPSPDVIVLSDSEQPSSPRVNGLTTVALKDTSTEALLKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTASSGSTVTTPPPLVRGTQNIPAGKTSLQTSSTRIPGSIIPPPLVRGGQQVSAKLGPQASSQVVMPPLVRGAQIHNIRQHSSTGPPPLLLAPRASVPSMQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTAASMKGTAVASAQANSTPTSVASVVASAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRISATAAAAVLSREPYMCVQCKTDFTCRWREKGGAVMCENCMTSNQKKALKVEHTSRLKAAFVKALQQEQEMEQRLLQQGVGTASIKAEPAAPHPTLKQVIKPRRKLAFRSGEARVWNNGSSLQASSQLSRGSATAPRGVLHTFSQSPKLQNAASATALVSRTGRHSERVVGTGKGTASNWKKTPLSTGGTLAFVSPSLAVHKTSSAVDRQREYLLDMIPPRSIPQSATWK
What is the function of this protein?
Transcriptional repressor.  Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin.  Enhances MBD2-mediated repression.  Efficient repression requires the presence of GATAD2B.
What are the official names of this protein?
Transcriptional repressor p66 alpha, GATA zinc finger domain-containing protein 2A.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled nuclear localization requires both CR1 and CR2 regions.
Protein: RECF_PHOLL
Sequence: MTLTRLLIRDFRNIAAADLPLATGFNFLVGSNGSGKTSVLEAIYTLGHGRSFRSIQAGRVILHGCDEFVLHGRLGQQENERERSIGLSKNRNGDSKVRIDGSDGGKIAELAKMLPMQLITPEGFTLLNGGPKYRRAFIDWGCFHNEPRFFSAWVNLKRLLKQRNAALRQVTRYSQIRPWDQELIPLANQINQWRGEYVTNITQDITNTCKQFLPEFTLSFSFQQGWDKESDYAELLERQFERDRTLTYTASGPHKADLRIRAEGTPVEDMLSRGQLKLLMCALRLAQGEYFTRQSGQQCLYLLDDFASELDTSRRQLLAARLKSTQAQVFVSAINPDQITDMLDGNSKMFRVENGKIEVQPQD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP2_LOTGI
Sequence: MNFRVVFLTVFLSVPFCCCQNVTELSGTSPNGSSLSGTNQNSEPQKGVINAGSTPSSGTLSIASLQAMLATLMMTNKQTVAAASKPTVTNTGSKQPTATGQPTLSQPRKQLILTNRRRNPRRWGRVFIDNKSNLCAFERQNFLNSFGLHDKLKKDIVENLNKIRKDVKAQNMNCLLWSEKLAAKAAKLVKECTYQNTNKAAITSMVYEKEIGDQLVGRSLSRWMDNKKYFSYGNDCRDTGGCQFSQIVWARSKIIGCAAERCSDMTNMVCLFEPKGNVRNELPYLTGNQCAQCSASRGSTPTCNKDKLCEWYFPRPKF
What are the official names of this protein?
SCP domain-containing protein 2, Uncharacterized shell protein 3, LUSP-3.
Protein: IMPA3_MOUSE
Sequence: MAPMGIRLSPLGVAVFFLLGLGVLYHLYSGFLAGRFSLFGLGSEPAAGEAEVASDGGTVDLREMLAVAVLAAERGGDEVRRVRESNVLHEKSKGKTREGADDKMTSGDVLSNRKMFYLLKTAFPNVQINTEEHVDASDKEVIVWNRKIPEDILKEIAAPKEVPAESVTVWIDPLDATQEYTEDLRKYVTTMVCVAVNGKPVLGVIHKPFSEYTAWAMVDGGSNVKARSSYNEKTPKIIVSRSHAGMVKQVALQTFGNQTSIIPAGGAGYKVLALLDVPDMTQEKADLYIHVTYIKKWDICAGNAILKALGGHMTTLNGEEISYTGSDGIEGGLLASIRMNHQALVRKLPDLEKSGH
What is the function of this protein?
Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate (PubMed:18695242).  May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation (PubMed:18695242).  Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4.
What are the official names of this protein?
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase, Golgi-resident PAP phosphatase, gPAPP, 3'(2'), 5'-bisphosphate nucleotidase 2, Inositol monophosphatase domain-containing protein 1, Myo-inositol monophosphatase A3, Phosphoadenosine phosphate 3'-nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Note=The catalytic core is predicted to reside within the Golgi lumen.
Protein: KDPA_SHIBS
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFAFIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: M5H41_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGALKELASTYLQRKRTAEEQHEVMKRLEAVMRDLDSLDHPEEASEREIRGFNQEEIANLFTKKEKRILGPVISKIGGVLGGLLKNLG
What is the function of this protein?
Maximin-H4 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 5/H4 type 1.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABPI_RHASA
Sequence: YQLESQEGFVPFSVSEIEQRVTVTTGSKTVVTL
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, I-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAMD_DELRA
Sequence: LPSIGHYY
What are the official names of this protein?
Neuropeptide Y-amide.
Protein: DXR_PLAF7
Sequence: MKKYIYIYFFFITITINDLVINNTSKCVSIERRKNNAYINYGIGYNGPDNKITKSRRCKRIKLCKKDLIDIGAIKKPINVAIFGSTGSIGTNALNIIRECNKIENVFNVKALYVNKSVNELYEQAREFLPEYLCIHDKSVYEELKELVKNIKDYKPIILCGDEGMKEICSSNSIDKIVIGIDSFQGLYSTMYAIMNNKIVALANKESIVSAGFFLKKLLNIHKNAKIIPVDSEHSAIFQCLDNNKVLKTKCLQDNFSKINNINKIFLCSSGGPFQNLTMDELKNVTSENALKHPKWKMGKKITIDSATMMNKGLEVIETHFLFDVDYNDIEVIVHKECIIHSCVEFIDKSVISQMYYPDMQIPILYSLTWPDRIKTNLKPLDLAQVSTLTFHKPSLEHFPCIKLAYQAGIKGNFYPTVLNASNEIANNLFLNNKIKYFDISSIISQVLESFNSQKVSENSEDLMKQILQIHSWAKDKATDIYNKHNSS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, 1-deoxyxylulose-5-phosphate reductoisomerase, DOXP reductoisomerase, DXP reductoisomerase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ACPH_ECOBW
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: END4_METLZ
Sequence: MIKLGFHVSIAGSLPLAVSRAQEAGCDTFQIFTRSPRVWAAKPIEPSIAEAFIDALNISGIGPVVDHMPYLPNPAAEKPEIYARSIFTMTEELDRCDQLKIPYLVTHLGHHGKEDGHKKGQEKVIAAIGQALDESEGETMILLENTANEKNTVGGTFTDIGVISDALSNERRVGFCFDTCHAAAAGYDLKGHGAETVFGWFNDEAGSLDRLKVIHLNDMKGGVGSHLDRHEHLGLGYLGEETIHDVLTFPKISHCAFIMETPSDEIRTDKDNLAVARRLAV
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: Y1666_STRS7
Sequence: MMNMQNMMKQAQKLQKQMEQKQADLAATSFSGKSAQELVTATFTGDKRLVNITFKEAVVDPEDIETLQDMTTQAINDALTQIDEATKKSLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SZO_16661.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS5_HAEIG
Sequence: MSNIEKQVGELQEKLIAVNRVSKTVKGGRIMSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNEGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVRNVLSKAYGSTNPINVVRATIDALANMKSPEMVAAKRGKTVDEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: 73C9_BARVU
Sequence: MVSEITHQSYPLHFVLFPYMAQGHMIPMVDIARLLAQRGVKITIVTTPQNAARFENVLSRAIESGLPISIVQVKLPSQEAGLPEGIETFESLVSMELLVPFFKAVNMLEEPVQKLFEEMSPQPSCIISDFCLHYTSKIAKKFNIPKILFHGMCCFCLLCMHVLRKNCEILENLKSDKEHFVVPYFPDRVEFTRPQVPMATYAPGDWQEIREDIVEADKTSYGVIVNTYQELEPAYANDYKEARSGKAWTIGPVSLCNKVGADKAERGNKADIDQDECLKWLDSKEEGSVLYVCLGSNCSVPLSQLKELGLGLEESQRPFIWVVRGWEKNKELLEWFSESGFEERVKDRGLLIKGWSPQMLILAHHSVGGFLTHCGWNSTLEGITSGIPLLTWPLIVDQFCNQKLVVQVLKVGVSAGVEEVTNWGEEEKIGVLVDKEGVKKAVEELMGESDDAKERRKRVKALGQLAHKAVEEGGSSHSNITSLLEDIMQLAQSNN
What is the function of this protein?
Possesses very weak glucosyltransferase activity toward 2,4,5-trichlorophenol (TCP), when assayed with high concentrations of TCP.
What are the official names of this protein?
UDP-glycosyltransferase 73C9.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ACT2_PLAFO
Sequence: MSEEAVALVVDNGSGMVKSGLAGDDAPKCVFPSIVGRPKMPNIMIGMEQKECYVGDEAQNKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVSPEEHPVLLTEAPLNPKTNREKMTQIMFETFDVPAMYVSIQAILSLYASGRTTGIVLDSGDGVSHTVPIYEGYVLPHAINRIDMAGRDLTYHMMKWFTERGHTFTTTAEREIVRDIKEKLCYIAMDYDEELKRSEEHSDEIEEIYELPDGNLITVGSERFRCPEALFNPTLIGRECPGLHITAYQSIMKCDIDIRKELYNNIVLSGGTTMYNNIGERLTKEMTNLAPSSMKIKVIAPPERKYSVWIGGSILSSLSTFQQMWITKEEYEDSGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm.  Polymerizes into longer and more stable actin filaments compared to ACT1/actin-1.  Has ATPase activity.  ATP hydrolysis leads to the formation of a stable intermediate ADP-inorganic phosphate (Pi) actin, which is followed by the release of Pi.  ATP hydrolysis affects filament stability; ADP-bound actin depolymerizes much faster than ATP- or ADP-Pi-bound actin.  Plays an essential role in male gametocyte development in the mosquito midgut, functioning in several processes including male gametocyte egress from host erythrocytes, formation of a beating flagellum and relocalization of ACT1/actin-1 to the cytoplasm.  On the basal side of the mosquito midgut epithelium, required for the development of ookinetes into sporogonic oocysts.
What are the official names of this protein?
Actin-2, Actin II, pf-actin II.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYDND_HYDCU
Sequence: MMRTHYCGQVTEILENQQVTVSGWVHRRRDHGGVIFIDLRDREGLVQVVVNPDNAEMFAIAERVRSEYVLKVEGKVCARTPETINPKMNTGKIEIVAESLEVLSSAEPIPFQLDDKHISEEVRLTYRYLDLRREEMQSTMRTRYRVTRSMRRYLDDNGFMDMETPILTKSTPEGARDYLVPSRTHPNKFFALPQSPQLFKQLLMMSGFDRYYQITRCFRDEDLRADRQPEFTQLDIETSFMTEEEVMNMMEGLTKTIFREGVDVNFEDDFPRMTYAEAIEKYGIDRPDLRIPLQLVDVADLLQDIDFKVFAGPAKDPMGRVAALRVPQGGKLSRKEIDDYTKYVGIYGAKGLAYIKVNDLSAGLDGLQSPIVKFFPDQAMEIMQRVGAEDGDIVFFGADNAKIVNEALGALRCKIGEDLDMIEKEWAPVWVVDFPMFEMDEKTAKMTAIHHPFTQPKATTEEILNHDEPHQMLSRAYDLVINGIEVGGGSVRIHDTHMQAAVLKMLGISDEDAQEKFGFLLNALKYGCPPHAGMAFGLDRLVMLMAKRDSIRDVIAFPKTQSAACMLTDAPGNVDNTQLADLELRFRKSLVAKDAS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_CORGB
Sequence: MAPKKTATKATAAKGNDRQKALDAALALIEKDFGKGAVMRLGDENRPPIQTISSGNTAIDIALGIGGFPRGRIVEVYGPESSGKTTVALHAIAQAQKAGGIAAFIDAEHALDPDYARKLGVDTDALLVSQPDTGEQALEIADMLVRSGAIDIIVIDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKMTGALYNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRCDIRRIQTLKDGQDAIGNRTRLKVVKNKVSPPFKIAEFDIMYGEGISRESSVIDLAVDNGIVKKSGSWFTYEGEQLGQGKEKVRLSLKENPELTDELEDKIFKKLGVGKYAAASDELTDDPVELVPNVDFDDEADTEADAED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_BACCR
Sequence: MPYRKYREKKYETKYREAFKVFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWEFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNVEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 14332_ECHMU
Sequence: MAAITSWITDSGCKDHASLVSIAKLAEQAERYEDMAVAMKTIAEMGNELNNEERNLLSVAYKNVVGARRSSWRIMSSIAKKQAGTPLADQTDIYLKKVEEELTKICNDVLALLSKNLITEKIGAEAKIFYYKMMGDYYRYLAEVQEGEQNDKSTEAAEEAYQKATSLAEAELSVTHPIRLGLALNFSVFYYEIKNMPEKACSLAKAAFDAAITEVDSIKDETYKDSTLIMQLLRDNLTLWNSECETDS
What are the official names of this protein?
14-3-3 protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: RPOC_ANASK
Sequence: MKDIFNFFEKPKDPLSFSAIRISLASPDKIRQWSHGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYKRMKHRGVVCEKCGVEVIQSKVRRERLGHITLATPVAHIWFLKSLPSRIGNLLDITLKDLEKVLYCESYIVIDPKETTFQRGELLSEDRYQKALDEFGDDAFSAGMGGEAVLGLLRGVGPASKEHGEGIPGLANELRAEMKEATSDAKRKKIAKRLKVVEAFVASGNKPEWMMLEVIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPDIIIRNEKRMLQEAVDALFDNGRRGKTITGPNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKIMALELFKPFIYNKLEEKGYVTTIKSAKKMVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQMEARVLMMSTNNILSPAHGKPIIVPSQDIVLGIYYMTRERAFARGEGKVFASPEEVRAAYDQGEVDLQAKVWVRMDGKRVETTVGRVLLYDIVPRRLSFESINKVMDKKQLQGLIDLTYRLCGEKETVLLADRVRSMGYGNATRAGISIALDNMVIPRKKVDLLERATREVDDIQAQYTEGLITIGERYNKVIDIWAQVTEEVAQEMMGEIGTETAVGTGKDGKREERRQPSFNPIYIMADSGARGSAQQIRQLAGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDAIITEYDCGAMDGITLGALVEGGEIIEPMGERILGRVALDDMLDPFSGNVLVKANEEIDEGKVKLIENAGIDKVKIRSVLTCQARRGICVECYGRDLARGRKVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRRAEQSTIENRNAGLIKFNNVSVAKKRDGTLIVMNRNGEIIVTDDQGRERERYGVVYGAKLLVREGQKVEANQLLAEWDPYSMPIITEVAGRVKYGDLVDGVTISEQVDEITGLARKAVIASKDPDARPRISIKDEEGRTKKLANSDADARYMLPEGANLVVNDGDEVDAGDVIAKMPRETTKTKDITGGLPRVAELFEARKPKEHAVISEIDGVVAFGKDTKGKRKVVITPEVDSKLRPDLAKEYLIGKGKHISVHTGDRVRAGEALMDGAANPHDILRVLGEKELARWLVDEVQEVYRLQGVKINDKHIETIVRQMLRRVRIVDVGDTEFLADEQVEKFAFEEENERVLKAGGRAAQGEPLLLGITKASLSTESFISASSFQETTKVLTEAAISGKVDYLRGLKENVIMGRLVPAGTGLGAYKHLDIEVETPVDAVEEAEEALAVGAEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SLMAP_MOUSE
Sequence: MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDDFLPKINGSTEKEHLLSKSGGDCTFIHQFLECQKKLMVQGHLTKVVEESKLSKENQAKAKESDLSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGTQSETEAKQDIQHLRKELVEAQELARTSKQKCFELQALLEEERKAYRNQVEESAKQIQVLQVQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQGELEKLKKEWDVLETECHSLKKENVLLSSELQRQEKELHNSQKQSFELTSDLSILQMTRKELEKQVGSLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWPWMPMLAALVAVTAMVLYVPGLARASP
What is the function of this protein?
May play a role during myoblast fusion.
What are the official names of this protein?
Sarcolemmal membrane-associated protein, Sarcolemmal-associated protein.
What is the protein family that this protein belongs to?
Belongs to the SLMAP family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type IV membrane protein. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum (By similarity). Detected along the Z- and M-lines in cardiomyocytes (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner.
Protein: HSDHB_COLAA
Sequence: MNLREKYGEWGLILGATEGVGKAFCEKIAAGGMNVVMVGRREEKLNVLAGEIRETYGVETKVVRADFSQPGAAETVFAATEGLDMGFMSYVACLHSFGKIQDTPWEKHEAMINVNVVTFLKCFHHYMRIFAAQDRGAVINVSSMTGISSSPWNGQYGAGKAFILKMTEAVACECEGTGVDVEVITLGTTLTPSLLSNLPGGPQGEAVMKIALTPEECVDEAFEKLGKELSVIAGQRNKDSVHDWKANHTEDEYIRYMGSFYRD
What is the function of this protein?
7beta-hydroxysteroid dehydrogenase that catalyzes the reduction of the 7-oxo group of 7-oxo-lithocholate (7-oxo-LCA), to yield ursodeoxycholate (UDCA) (PubMed:21181147, PubMed:6954878, PubMed:27006087).  As C. aerofaciens is an intestinal bacterium, this enzyme probably contributes to the formation of UDCA in the human colon.  UDCA is regarded as a chemopreventive beneficial secondary bile acid due to its low hydrophobicity; it protects hepatocytes and bile duct epithelial cells against necrosis and apoptosis induced by more hydrophobic secondary bile acids like deoxycholate (DCA) (Probable).  This enzyme is also able to catalyze the reverse reaction, i. e.  the oxidation of the 7beta-hydroxy group of UDCA to 7-oxo-LCA (PubMed:21181147, PubMed:6954878).  To a lesser extent, is also active on the taurine- and glycine-conjugates of ursodeoxycholate.  It is specific for NADPH/NADP(+) as the electron acceptor/donor since it is not active with NADH/NAD(+) (PubMed:6954878).  In the presence of NADPH, 7beta-HSDH can also reduce dehydrocholate (PubMed:21181147).  And is also able to oxidize ursocholate (PubMed:27006087).
What are the official names of this protein?
7beta-hydroxysteroid dehydrogenase, 7beta-HSDH, NADP-dependent 7beta-hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL20_XANAC
Sequence: MARVKRGVQARRRHKKILTLAKGYYNARRKVFRVAKQAVIKAQQYAYIGRKQKKRNFRSLWITRINAAARINGLSYSRFMNGLLKAGITLDRKVLADIAVHDAAGFAALAEKAKGALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TIG_OCEIH
Sequence: MTAKWEKQEGNKGVLTFEVSAEEFEQALDQAFKKVSKDVQIPGFRKGKIPRGIFEKRFGVEALYQDAVDIVLPSAYTKAVEEADIFPIAQPSVDIDQIERGKELIFTAEVEVKPEVKLGEYKGLEVEEESVEVTDEDVEKEIENVRERHAELIVKEEEAIENGDTAVIDFEGFQDGVAFEGGKGENHSLEIGSGQFIPGFEEQLIGKKAGEETEVTVTFPEEYHAEDLAGKEAVFNVKINEVKAKELPELDDEFAKDVDEEVESLDELKKKKRNELETNKKQEVENKKREELIQKASDNVEVDIPEAMVDTEVNQMVREFEQQLQMQGMTLEMYAQFSGQDEDALKEQMREDAAKRVKTNLTLEAISEAEGIKPSEEDIKAELEKMASMYGAEVDQLVQMLGGNTETLENDLKVKAAIDFLAENSKTK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.