PharMolix/UniProtQA huggingface dataset:
Protein: ACUK_AJEDR
Sequence: MTASTRNGSPSPSPAAPTATEQESKSMTTTPANPPETKSQTNGKGSGTAQSSQKPASTSANAKDPLRPRRKKAKRACFACQRAHLTCGDERPCQRCIKRGLQDACHDGVRKKAKYLHDAPNEALLPGIRGNYYNQANTTRNIPNQRGNASNSNSNKVSRQSVSSANFYTPQAARSYNVYVQAKSQQSHVRPAVMQDASMNPSVFHAQSPSSTQNFDLSSNPQTQNLSSAMSQTASSVSGQNQDPFGAAFFDPSHPALFNFDIASMNFGNRYGALEFGMLGHMATGAGDTPPSDSATQRGSIGRSSGTFTAQNFGDSANNQSPFLFGDPVLNDWNPTGQGQANPRNIYNQNAVAGQMGEQNPHAFAIESAPMNFASPSSTESPQMTTTTPFDEANANFSSRTNLMHPTNTPQQSRISTPGLKHQGLHVGVKRRYRSPSSIYESVKEPYSYTSGFHSLTAFIQRRFSPQKTLQIAKALASIRPSFIATTKTLNQDDLIFMEKCFQRTLWEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWKKEVLLGKEPNLNVNTGSSLSSASSVRGSSTFTPRNNNTHNSIDPHTGMPTVGGGGASGRTQPVFLAELLDDDSVIEFYEDFAKLAFGDSRGSVMTTCKLLKYKTKEDSAALFHGKEETQQGGVDGSSGTGTTTSGDVATTTATGTSTSNGANANTNGNNTNPNDPSSAASSSASSALQGPQQSPRQTWGKRGIAGEAGMNQLGFRDGKVECSYCWTVKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis BDCG_02812.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GNTR_ECOLI
Sequence: MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAALDELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYGYKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAVGFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVEQSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI
What is the function of this protein?
Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon.
What are the official names of this protein?
HTH-type transcriptional regulator GntR, Gluconate utilization system GNT-I transcriptional repressor.
Protein: ULAR_ECO55
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DS_VALOF
Sequence: MSTALNSEHETVRPLASFQPSTWGDLFISYSEDSQLKEVYGKEHECLKQQVKTMLLDVTNYRISEKIAFINTLERLGVSHEFENEIEGLLHQMFDAHSKFQDGIQHFDLFTLGIYFRILRQHGYRIYCDVFNKLKDSNNEFKKELKEDAIGLLSLYEATQVRAHAEEILDEALIFTKAQLESIAATSSLSPFVEKQITHALVQALHKGIPRVESRHFISVYEEDPDKNDLLLRFSKIDYNIVQMLHKQELCHISKWWRDSELETKLTYARNRVAECFLWTLCVYHEPKYSPARLLLGKLINIISCTDDTYDAYGTLEEVQIFTDVIQRLDRSSMEQLPDYMKILYKAVLDLFDEVEVQLSNQETNNTYRMAYAKEELKAIAKCYEKEHIWFRKCHVPPFEEYLENAVVSIGNRLAVTFSFLGMDQVAAVEAFEWAKTDPKMVKSCGKVLRLVDDVMSHEEEDVRGHVATGVECYMKEHGVSREEAVVEFYKRVEYAWKDVNEEFITPNHLHIDLLNRVLNLTRIADVVYKFEDGYTHPEKTLKHHIMALFVDPVPI
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into drimenol, a precursor of the sesquiterpenoid polygodial (PubMed:25447532).  Polygodial has been shown to be an antifeedant for a number of herbivorous insects (Probable).
What are the official names of this protein?
(-)-drimenol synthase, VoDMS, Drimenol cyclase, Sesquiterpene synthase 3, VoTPS3.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ACDH1_BURVG
Sequence: MATDNTRCKAAIIGSGNIGTDLMIKIMRSGKHLEIAAMVGIDPASDGLARAARLGVATTHEGVEGLARLPVFDEIDFVFDATSAGAHVKNDAFLRALKPGIRMIDLTPAAIGPYCVPVVNLDAHLDAPNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASISSKSAGPGTRANIDEFTETTSKALEAVGGAGKGKAIIVLNPAEPPLMMRDTVYLLSEAADRALIEASVSEMAAAVQAYVPGYRLKQSVQFDDIPAAAPLHIPGLGRFSGLKTSIFVEVEGAAHYLPAYAGNLDIMTSAALATAERMAASLVNA
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: LICH_BACLI
Sequence: ISLEICXIFHDN
What is the function of this protein?
Oxygen labile bacteriocin-like.  Has antibacterial activity only against strictly anaerobic rumen bacteria.
What are the official names of this protein?
Lichenin.
What are the subcellular locations of this protein?
Secreted.
Protein: YJGA_SALNS
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAELVDLGKNALDKIPLDADLRDAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLEHLRDRLIVEGDDAVAEVLTLWPHADRQQLRSLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: NRDR_STRT1
Sequence: MRCPKCQHNKSNVIDSRQAEDGNTIRRRRECDACHARFTTFERVEEVPLLVVKKDGTREQFSRDKIFNGILMSAQKRPVSSEDIENAITRIEQNIRRNHDGEVDSEVIGNLVMKELADLDEITYVRFASVYRSFKDVDEIEELLQEITKTVRAKKESKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS18_ESCF3
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MYPT2_HUMAN
Sequence: MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKDKERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEIPQTIAPSTYVSTYLKRTPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPVLSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHRLRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK
What is the function of this protein?
Regulates myosin phosphatase activity.  Augments Ca(2+) sensitivity of the contractile apparatus.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12B, Myosin phosphatase-targeting subunit 2, Myosin phosphatase target subunit 2.
Protein: HEMW_LACLA
Sequence: MLQKPNSAYFHIPFCSHICYYCDFAKVLMTGQPIDAYIESLIEEFQSFEIEKLRTIYIGGGTPSVLSAQQLERLLTAIAEQLDLEVLEEFTVEANPGDLSDEVIKVLADSAVNRISLGVQTFNNALLKKIGRTHTEVQVYDSVERLKKAGFENITIDLIYALPGQTMEMVKSDVEKFLELKLPHVALYSLILEDHTVFMNRQRRGLLRLPSEDKNADMYEYIMDILAKNGYNHYEVSNFGLPGFESKHNITYWDNEEYYGIGAGASGYLAGIRYKNLGPVHHYLKAAPTEKRINEEVLSKKSQIEEEMFLGLRKKSGVLVEKFENKFKCSFEKLYGEQITELINQKLLYNDRQRIHMTDKGFELGNNVFEKFLLDDINF
What is the function of this protein?
Could serve in the delivery of heme to a membrane-localized target protein (Probable).  Binds one molecule of heme per monomer, possibly covalently; heme and Fe-S cluster binding are independent.  Incubation with the reductant sodium dithionite increases binding.  Does not have coproporphyrinogen III dehydrogenase activity in vitro, does not complement an E. coli hemN deletion in vivo (PubMed:22142238).  Binds 1 Fe-S cluster, it is probably [4Fe-4S].  The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; only dimeric protein has the cluster (Probable).
What are the official names of this protein?
Heme chaperone HemW.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=A minor, heme-containing fraction is associated with the cell membrane.
Protein: MNMG_MAGSA
Sequence: MRLTKYGVFHVKQTSSCDVVVIGAGHAGCEAAAAAARFGARTVLLTQRLETIGEMSCNPAIGGLAKGQLVREIDAMDGLMGRVIDRAGIQFRILNRSKGAAVQGPRAQADRKLYRLAMRAALDETENLSLLEGSAEDLVITDGRVAGVVLADGSTIACGAVVITTGTFLRGLIHLGEKTWPAGRVGDAPSLGLSLALERAGLPLGRLKTGTPARLDGRTIHWDSLDRQEGDDPPVPFSYLTERITTPQVACGITATTPETHAIIRANLERAPMYSGQIQSTGPRYCPSIEDKVVRFADRERHQIFLEPEGLDDHTVYPNGISTSLPEDVQLAMIATIPGLEQCRVIRPGYAIEYDFVDPRALHRSLETKGVGGLFLAGQINGTTGYEEAAGQGLMAGLNAARRCAGSAPLVLDRADAYLGVMIDDLVSLGTSEPYRMFTSRAEYRLLLRADNADSRLTPKGREAGCVDSERWAAFMVKAAGLERGRALLQSLKGSPDWLRRQGLEINRDGVVRSAWDLLAYPELGLQALAAVWPELDSLSGAVAEQLEIEGRYAGYLDRQEADIRAYRREEGLALSADLDYDAIGSLSNEVRQKLKAARPETLAAAARIPGVTPAAVTALLGHVKKMVLDWAEGPVP
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP6_ORYSI
Sequence: MTGGSGVVVLDNGGGLLKAGFGGDMNPTAVVPNCMAKPPGSKKWLVADQLQAQDVDVTGMTLRRPIDRGYLINQEVQREVWERVIRNLLQVDPNNSSLLLVEPQFNPPALQHATDELVFEELGFKSLCVADAPSLVHLYEASRQPSLFRAQCSLVVDCGFSFTHASPVLQNFTLNYAVRRMDLGGKALTNYLKELISYRSLNVMDETLLIDDAKEKLCFVSLDVPGDLRLARLSSNDNPFRCSYILPDGITYKKGFVKDLDEACRYSSLPANGESVRKDSSDSDRSKFEDKKKPELSQNEFVLTNERFLVPEMLFHPIDLGMNQAGLAECIVRAIQACHPHLQPVLFERIILTGGSTLFPRFTERLEKELRPLVPDDYQVKIIAQEDPILGAWRGGSLLAHRPDFESMCITKSEYEEMGSMRCRRRFFH
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A. F/Z leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in several developmental processes.  May be involved in the regulation of pathogenesis-related proteins (PRs) (By similarity).
What are the official names of this protein?
Actin-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL332_LACDB
Sequence: MAVKKAALACSVCGSRNYSITANSNRTKRLELNKFCKHCGKKTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DUT_YERP3
Sequence: MKKIDIKILDPRVGNEFPLPTYATEGSAGLDLRACLDHAVELQPGQTTLLPTGLAIHIGDSALAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSVWNRGQQPFTIEPGERIAQMVFVPVVQAEFNLVEDFTDSERGTGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TAL_CHLPB
Sequence: MKFFIDTADLEEISAANDLGVLDGVTTNPSLVAKIVSDPEKFTYQDFKDHIAKVCEIVDGPVSAEVTTLSPEEMISQGEELAAIHDNVVVKCPLTRDGLKAMRHLSGNGIRINATLVFSPSQAILAAKAGASYVSPFVGRLDDISTEGMALVDQIVRIYDNYRFPTEVLVASIRHPQHVVEAALMGADIATIPFDVIGQLLKHPLTDSGLKRFMDDASVIQQG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P53_FELCA
Sequence: MQEPPLELTIEPPLSQETFSELWNLLPENNVLSSELSSAMNELPLSEDVANWLDEAPDDASGMSAVPAPAAPAPATPAPAISWPLSSFVPSQKTYPGAYGFHLGFLQSGTAKSVTCTYSPPLNKLFCQLAKTCPVQLWVRSPPPPGTCVRAMAIYKKSEFMTEVVRRCPHHERCPDSSDGLAPPQHLIRVEGNLHAKYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNFMCNSSCMGGMNRRPIITIITLEDSNGKLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCPEPPPGSTKRALPPSTSSTPPQKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQSGKEPGGSRAHSSHLKAKKGQSTSRHKKPMLKREGLDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress (By similarity). Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: G3P_METFE
Sequence: MKAVAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEARMALKKGYDLYVAIPERVKLFEKAGIEVAGTVDDMLDEADIVIDCTPEGIGAKNLKMYKEKGIKAIFQGGEKHEDIGLSFNSLSNYEESYGKDYTRVVSCNTTGLCRTLKPLHDSFGIKKVRAVIVRRGADPAQVSKGPINAIIPNPPKLPSHHGPDVKTVLDINIDTMAVIVPTTLMHQHNVMVEVEETPTVDDIIDVFEDTPRVILISAEDGLTSTAEIMEYAKELGRSRNDLFEIPVWRESITVVDNEIYYMQAVHQESDIVPENVDAVRAILEMEEDKYKSINKTNKAMNILQ
What is the function of this protein?
Exhibits a dual-cofactor specificity, with a marked preference for NADP(+) over NAD(+).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_BRADU
Sequence: MTMIGWLQIILFCVIIVALTKPLGWYMTRVFNGERTFLSPVLRPIEAGIYWISGVDERREQHWLTYTVAMLLFHVGGFLVIYGVMRLQAVLPFNPAGQSAVAQDLSFNTAISFITNTNWQNYGGESTLSYLVQMLGLTHQNFLSAATGIALAMALIRGFSRASVRTVGNFWVDVTRCTLYVLLPICVVYTLFLVWQGIPQTLGDYVEATTLEGAKQTIAVGPVASQVAIKMLGTNGGGFFNANAAHPFENPTALSNFVQMLSIFALGAALTNVFGRMVGNQRQGWAILAVMGVLFVAGVAVTYWAEANGTSTMHALGLTGGNMEGKEVRFGLVASSLFAVITTAASCGAVNAMHDSFTALGGMIPLINMQLGEIIVGGVGAGLYGMLLFVVLAIFVAGLMVGRTPEYVGKKIEAREVKMAMLAILVLPLMYLGWTAVGVVYPAAVASMANAGPHGFTEVLYAFTSATGNNGSAFAGLTGNTLFYNLTLASAMFVGRFFMIVPAMAIAGSLAAKKSIPPSAGTFPTTGGLFVGLVVGVILIIGGLTFFPALALGPIVEHLAMNAGQVF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_STRPG
Sequence: MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVGGDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: LDH3_BACCR
Sequence: MKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMASGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREVVELNLTEDEESRFAKSNDILRDYMKTIGY
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 3, L-LDH 3.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRRA1_MOUSE
Sequence: MVSSGMYKMDNGKPCLNNCFPAKSLLRLPEEGRGHWIVVRKGSMKKGAAKASTEGQESQKKVSFDTGLKKISRRDSQADVLGHILDRSFLLKHHSARKPSDLCTINVSGMKFSKAKEKDFKHFTSVIYINASENLLPLDVFHTFPVLKELELAFNGIKMVYVKYGDFKTLEFLDLSFNSLTEEAICDLGILPHLRVLLLTGNGLTSLPPNMAVKEQEASMTSLTSKKYILRFPALETLMLDDNKLSNPSCFASLAGLRRLKKLSLDQNKIVRIPYLQQIQLRDGSGDWVTEGPNPQKELQPQMWIFETPDEQPNYTVLPMKKDVDRTEVVFSSYPGFSTSETAKVCSLPPMFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPAALFPSLCELVFHNNPLVAHTRGIPPLLKSFLQDRLGIRLVRKKLVKPKHHMLMPRKESRKVKTYIPKVPKHSLVPHHLNMITDSPPSSLMPEPEHSTEDTSHEALFANEGPEGPSLTHRAFVPMPPICSDSTVHSEAVSHQSHTAGLVSSEHPSDDDAKSTESIFLTQVNELPSSTAHRENLEAVNDQRRPSTAPRETKRTRRKQTATSLHNKYDGYEELLTVKPDPAFLEPKGIQKNAQALHRMLKQPLICRSSKPRLDTFQKPYVPKEKRAGRIPILPPRKTRAQLLDDILIRMRDPRNVTEAPLGTVLQRRAQQRLVNQKQYREAKRLLKEFRARYRQLVRSSLRTVFAASPPPRPPTRRALSAGQPKLGRFLEFMDEFCQEPTASDSKE
What is the function of this protein?
May be involved in the response of cells to X-ray radiation.
What are the official names of this protein?
X-ray radiation resistance-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IF3_BACFR
Sequence: MKNDSMKSQYRINEQIRAKEVRIVGDDVEPKVYPIFQALKLAEEKELDLVEISPNAQPPVCRIIDYSKFLYQLKKRQKEQKAKQVKVNVKEIRFGPQTDDHDYNFKLKHAKGFLEDGDKVKAYVFFKGRSILFKEQGEVLLLRFANDLEDYAKVDQLPVLEGKRMTIQLSPKKKESATKKPATPKPATPAAVKAEKPAGDNEE
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_ECOLI
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKG
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RECO_STAAT
Sequence: MLMRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGLQAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLYVSSYAALAAETIERSMDEGDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQADLIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEMSDIILMLYREYAGMFFKSQKLINQLKRLEQ
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CHI4_CRYJA
Sequence: MQIMATQNSKSNIFWSSSASVVLVLLLLVDVGVCQNCGCNGLCCSQYGYCGSGEAYCGAGCKEGPCSSSSPPSTGTGVGSIVSSDVFNSIVGGAASGCAGNGFYTYDSFISAANAFNGFGTSGSSDVNKREIAAFFANAAHETGGFCYIEEQNPTSIYCDASNTQYPCASGKTYHGRGPLQLSWNYNYGAAGSYIQFDGLNNPEIVGTDSTISFKTAVWFWMVNSNCHTAITSGQGFGATIRAINSMECDGGNAATVASRVNYYQKFCQQLNVDTGSNLQC
What is the function of this protein?
Has endochitinase activity (PubMed:15725197).  Hydrolyzes chitin oligosaccharides, GlcNAc(n), with different degrees of polymerization (n=2-6), a soluble substrate glycol chitin, and an insoluble substrate beta-chitin nanofiber in vitro.  GlcNAc(6) is hydrolyzed at the second glycosidic linkage from the reducing end in addition to the middle linkage.  GlcNAc(4) is further hydrolyzed to GlcNAc(2).  Has antifungal activity against hyphal growth of H. rufa (PubMed:29756783).
What are the official names of this protein?
Endochitinase 4, Chitinase class IV, CJP-4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class IV subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYK_STRPS
Sequence: MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQELKDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETIYRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIKEITGVDFWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVSPLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATGIDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCF11_YEAST
Sequence: MDHDTEVIVKDFNSILEELTFNSRPIITTLTKLAEENISCAQYFVDAIESRIEKCMPKQKLYAFYALDSICKNVGSPYTIYFSRNLFNLYKRTYLLVDNTTRTKLINMFKLWLNPNDTGLPLFEGSALEKIEQFLIKASALHQKNLQAMLPTPTVPLLLRDIDKLTCLTSERLKNQPNDEKLKMKLLVLSQLKQELKREKLTLNALKQVQMQLRQVFSQDQQVLQERMRYHELQQQQQQQQQQQQQQQQQQQQYHETKDMVGSYTQNSNSAIPLFGNNSDTTNQQNSLSSSLFGNISGVESFQEIEKKKSLNKINNLYASLKAEGLIYTPPKESIVTLYKKLNGHSNYSLDSHEKQLMKNLPKIPLLNDILSDCKAYFATVNIDVLNNPSLQLSEQTLLQENPIVQNNLIHLLYRSKPNKCSVCGKRFGNSESEKLLQNEHLDWHFRINTRIKGSQNTANTGISNSNLNTTTTRKNIQSRNWYLSDSQWAAFKDDEITSTKHKNDYTDPHANKNIDKSALNIHADENDEGSVDNTLGSDRSNELEIRGKYVVVPETSQDMAFKCPICKETVTGVYDEESGEWVWKNTIEVNGKYFHSTCYHETSQNSSKSNSGKVGLDDLKKLVTK
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex.  Independently involved in RNA polymerase II transcript termination.  Binds RNA.  Seems to bridge RNA polymerase II and the native transcript and may be involved in dismantling the RNA polymerase II elongation complex.
What are the official names of this protein?
Protein PCF11, protein 1 of CF I.
What are the subcellular locations of this protein?
Nucleus.