PharMolix/UniProtQA huggingface dataset:
Protein: DCD_CUPTR
Sequence: MSIKSDKWIRRMAEQHGMIEPFEPGQVREADGRKIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEKSFVDFKGDVCIIPPNSFALARTMEYFRIPRSVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEICETSYADRGGKYQGQHGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: YBAB_SALTI
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YIDD_SYNWW
Sequence: MQEMLIKLIKIYQKATFFKPASCRFYPSCSNYSIEALRKYGIVKGGWLTVKRLARCHPYNPGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PURA_HELHP
Sequence: MADLIVGIQWGDEGKGKVVDALAGEYDYVVRYQGGHNAGHTIVVDSKKIALHLLPSGILYERCKNVIGNGVVINLEQLLNESKAFGNLQGRLFISDRAHIILPYHEILDIAKEKSRQSAAIGTTGKGIGPCYGDKVSRNGVRLMDLKNLDKLREKVDSIYQHIQYVQTLYNVELPSVQSVMEHIESIAPQILPFVTDTTQLLWAAQNRGEKILCEGAQGSMLDIDHGTYPFVTSSTTIASGACSGSGLAPRDIARVIGVAKAYCTRVGNGMFPTQEDGEIGERLRQAGGEFGTTTGRARRCGWFDAVAVRYACRLNGCESLSIMKLDVLDGFERVKVCVGYEYEGKQIDYIPTDYDNVKPIYREFVGWDKTCGVRTFNALPSQAQHYIKELEKIIGVKISMVSTSPERDDMIMLG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_MYCUA
Sequence: MTRLVLGSASSGRLKVLQQAGVDPLVVVSGVDEDAIMAGLGPAATPADVVRVLARAKAEQVATTLTGQQASVAADCLVIGCDSMLYIDGRLCGKPETVDDARQLWRSMAGRCGHLYTGHSVVRLTEQRVTHRDDETSTTTVHFAAPSDDDLEAYLATGESLKVAGGFTLDGLGGWFITGVEGDPSAVVGIGLPLTRDLISRAGISIAALWASNPLP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_KINRD
Sequence: MSDDRRLAVLRAIVEDYVSSHEPVGSKALVERHQLGVSPATIRNDMAVLEEEGYITQPHTSAGRIPTDKGYRLFVDRLANVKPMSPAEKRAIQTFLEGADDVDDIVDRTVRLLAQITRQAAVVQYPSLSRAAVRHVELVPVGGRSALLVLITDSGRVEQRVLDVRSAADPESLAAALAALRTRVNARVVGKRLRDAREDLTDLVQQTPPGDLAVAAEVAVALGDCLTAGLEERVVIAGTANLVKSGADLSTSLGSVLEALEEHVVLLRLVQELTEDSDRGGLTVRIGAENLHLGLDGTSVVTSGYGTGPDTVLARLGVLGPTRMDYPTTMAAVRAVSRYVSRILAQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: CTSRB_MOUSE
Sequence: MESPLIYVMLVLLNVFVFSSGVIHNKGKERTYFSCSGEGILTGLHTIKLFLTMDNLKVRCFFRNENQSPSKEILGLFTSGGLAPNMIITNSTFYGGYYFKLTPFSNRLEWLIDIPRQNITVNTDIAAVEQWMIKITMHEGLNIYDTEGTLLDLVREPILQWNLGRVLTEMEVRDLYPEVNDIKVTKSPCANDVALIGFMMKPSSNGVFIGKTISGFWTYKECIWHDLTEIIYAELKDEHQGLTVIDLVLTNHFLVILTSLGLYVSSDLRYPTTSQIKLSRAEFCGFERVDYIRGNLWYNEKCFANRESFEVDYVTITFNRNRTLSESSSCFFSKEPFLHWLPCVFSTIKNEKSIPRVITFLIDQETDSGIYLFNVQDTKETYVTVAMLKDGKPSPRPKFPSFHFPSTFTLPLGMIFHPRSHFLYVYGSQIWVSMDGGNTFEMLCNLFSHHVTKTSNSFYTSDIVFIVEDGRILTTKAGLTTYSELGILKDAIFTLYYDQLGYIHKLTPENFDAGSKLLGHGNSGSIFGKRPDLGFEAILVPQYISTNEMYFFAHVPLTMPTNIQWKKRFKTIHLGKTIEFSKTGLANIKNVYMHKTEPVGFQTSIHTEIIVPFGIENSKDSPCLLSDLEITYSGKLYYTIKLLSKNPLHELKSTDVEKSVLIPGYSSFLIMNITDKWTASALATMPQAIKSNLKFLTGSWFLYNFGTAGGRKWSISTRQCNYWIQQDSLDFMSLNLVKYIDVGNTIDFQFKIIPKAMSTFPIPPVSMVVGNPGLVEVKTQGVFDLNENYYLDIHVSGRFFQKGSTSIALVLWEGSSKCYAITLLPTIKSSCSYLRTMHHTPGRHIPPEDWISGVHKDSQGFNMIKTLPINYRPPSHMGISIPLTDNFYHADPSKPIPRNQFHKSKETGKYKQCANVTSRAMCNCSEHQKFSHAVAFSDCKEKVHRFKFPVTQYPVVLEIFNERDKISAEPPYLVTMTEVNMRKNWQLKHNEPENVKKMKHYLEPLLKTPVYNPLGLNLTIQGSELFHFKVSVVPGVSFCELSEEFQIYVDEVPLPFPGHALIAVATSVVLGVLIFIAFVFQLRNIHPLKALKKSIRGNPGLTSSTTVSS
What is the function of this protein?
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation (PubMed:34225353, PubMed:17478420).  Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (PubMed:17478420).
What are the official names of this protein?
Cation channel sperm-associated auxiliary subunit beta, CatSper-beta.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Single-pass membrane protein. Note=Predominantly located in the principal piece of the sperm tail.
Protein: HEMA_INBVK
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALARPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYEHIRLSTHNVINAETAPGGPYKVGTSGSCPNVTNGNGFFATMAWAVPKNDNNKTATNPLTVEVPYICTEGEDQITVWGFHSDSETQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGVAVAADLKSTQEAINKITKNLNSLSELEVKNLQRLSGAMDELHNEILELDEKVDDLRADTISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSAVEIGNGCFETKHKCNQTCLDRIAAGTFNAGEFSLPTFDSLNITAASLNDDGLDNHTILLYYSTAASSLAVTLMIAIFIVYMVSRDNVSCSICL
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: TRPB_HAEI8
Sequence: MSDTLLNPYFGEFGGMYVPEILVPVLKQLEQAFVEAQNDPTFQAEFADLLKNYAGRPTALTLCRNLTKCTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALACAMLDMPCRVYMGAKDVERQSPNVFRMRLMGAEVIPVEKGSCSLKDACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREFQKMIGEETKRQILEREGRLPDAVIAAVGGGSNAIGMFTDFIDEPNVRLIGVEPAGKGIESGEHGAPLGHAKVGIYFGMKSPLMQTEDGQVEESYSVSAGLDFPSVGPQHAYLNEIGRADYVSITDEEALNAFQELAKHEGIIPALESSHALAYALKLIKQNPEKEQLLVVNLSGRGDKDIFTVDKILNGGTN
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYN_YERPA
Sequence: MSVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPNYQDEVLHLTTGCSVEVTGTVVASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVSTPLITASDTEGAGEMFRVSTLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNTSRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRLQRFVTSDFAQVDYTDAIEILLASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBU_PROM3
Sequence: MKRLLSLLTGVLVMTGLLMALIFPQSAYANVSDEKLGDRGEKVDLNNSSVRAFRQFPGMFPTIAGKIVVGGPYSSVSDASSVLDASQKSVFDKYKDNFTVTDQEIAVNEGFDRINDGQYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: GPI14_NEUCR
Sequence: MATTSPAAPRPKSKSSSLLSTLFSRPLPLYVSAFLLRIVLLLYGLWQDANSPLKYTDIDYLVFTDAARFVSRGESPYARETYRYTPILAWLLLPTTWTAGAQWGPWAAKVINVAWFSFGKVLFAAADLVAGWLIEQVLVMGKDFPSSAAKGKEKDTEKTKEGGKKGPSVTASTGMDPSRARAFAAIWLLNPMVATISTRGSSEGLLGVLVMALLWAVLSRRITLAGLLLGFSVHFKIYPFIYAPAIVWWMDQERLSGVRAGGGGGGGGQKKTSSSFRKTLTRFLTLPRLLLAFTSLATFLSLNFLMYRLYGHPFLQETYLHHVTRIDHRHNFSPYNTQLYLSSASVSPSHSAAEPKFKIESLAFLPQLVLSTILIPLTLAKKDLPTSLLAQTFAFVTFNKVCTSQYFLWYLVLLPLYLPRSSFWTSKRMGLVALGLWVLGQALWLQQAYELEFLGRSTFLPGLWMASLGFFVVNCWILGVIVGDGGR
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.  Required for cell wall integrity (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Glycosylphosphatidylinositol-anchor biosynthesis protein 14.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ZN346_PONAB
Sequence: MEYPAPAAVQAADGGGAGPYNSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALSKRLTNPFLVASTLALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
What is the function of this protein?
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity.
What are the official names of this protein?
Zinc finger protein 346.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5 (By similarity).
Protein: RPOA_NEIG1
Sequence: MQNSTTEFLKPRQIDVNTFSATRAKVSMQPFERGFGHTLGNALRRILLSSMNGFAPTEVAIAGVLHEYSTVGGVQEDVVDILLNIKGIVFKLHGRSQVQLVLKKSGSGVVSAGDIELPHDVEILNPGHVICHLADNGQIEMEIKVEQGRGYQSVSGRQVVRDENRQIGAIQLDASFSPISRVSFEVEPARVEQRTDLDKLVLDIETDGSIDPEEAVRSAARILIDQMSIFADLQGTPVEEVEEKSPPIDPVLLHPVDDLELTVRSANCLKAEDIYYIGDLIQRTETELLKTPNLGRKSLNEIKEVLASKGLTLGSKLEAWPPVGLEKP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: STRP2_HUMAN
Sequence: MEDPAAPGTGGPPANGNGNGGGKGKQAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENLEFTNNRRCFEEDFKTQVQGKEWLELEEDAQKAYIMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape.
What are the official names of this protein?
Striatin-interacting protein 2, Protein FAM40B.
What is the protein family that this protein belongs to?
Belongs to the STRIP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched in lamellipodia.
Protein: SRC_AVISR
Sequence: MGSSKSKPKDPSQRRCSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATEPKLFGGFNTSDTVTSPQRAGALAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEYLQAQLLPACVLEVAE
What is the function of this protein?
This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro.
What are the official names of this protein?
Tyrosine-protein kinase transforming protein Src, pp60v-src, p60-Src, v-Src.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: GATB_STAES
Sequence: MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNRRAVDWAMRASMALNMDIATNSKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKDGYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDCKMEEGSLRCDANISLRPYGQKEFGTKTELKNLNSFNYVKKGLEYEEKRQEEELLNGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYVDEDWKARVRETIPELPDERKAKYVNDLGLPEYDAHVLTLTKEMSDFFEGAIDHGADVKLTSNWLMGGVNEYLNKNQVELKDTQLTPENLAGMIKLIEDGTMSSKIAKKVFPELAENGGDAKQIMEDKGLVQISDEATLLKFVTDALDNNPQSIEDYKNGKGKAMGFLVGQIMKASKGQANPQKVNSLLKQELDNR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: HEMH_DESPS
Sequence: MQNIPTGVILLNMGGPTQTKDVRPFLYNLFSDREIIPLGPRLMQKPLAWLIAKRRAPKSAATYERIGGGSPLKQITEAQAEALEKSLQAHGNFTVTYAMRYWPPYCDEALDYLLSKGVERLVALSLYPHYSKATTGSSLTQLHKTLKKKNISLPLTEIPSWPKQRDYIAAIAANIKKGLATFHGEKTEIVYSAHSLPTSFIEAGDPYVEHTKQSIGAIEEITGKRGRLCFQSKSGPVEWLEPSTPDVLIQLAQEGVKNILMVPISFVSDHVETLYEIDILYKKQAKKLGMRLTSCPSLNTQEQFITGLRQLVLESSVNSD
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRCA_YERPA
Sequence: MITGIQITKANNEALLNSFWLLDDEKAELRCVCAKSGYAEDQIVPTSELGEIEYREVPLEVQPTVRVEGGQHLNVNVLSRDTLEDAVKNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: PYRD_SALCH
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPTKPVTCMGLTFKNPLGLAAGLDKDGECIDALDAMGFGSLEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKVYAYAGYIAINISSPNTLGLRTLQYGDALDDLLTAIKNKQNDLQAIHHKYVPVAVKIAPDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKSTEIIRRLSQELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSBF_NICGU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: 1106L_ASFP4
Sequence: MLVIFLGILGLLASQVSSQLVGQLRPTEDPPEEELEYWCAYMESCQFCWDCQDGTCINKIDGSVIYKNEYVKSCLVSRWLDKCMYDLDKGIYHTMNCSQPWSWNPYKYFRKEWKKDEL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-6L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum lumen.
Protein: DNSL1_CRIGR
Sequence: MPYMAMHGLTVALLLIFLAGGTEAFRICAFNAQRLTLSKLAKEPVMDTLVQILARCDIMVLQEVVDSSQKTVSLLLRELNRFDSSRTYSFLNSSLLGRSTYKEKYVYIYRSDKTQILNSYQYNDTNDLFAREPFVAQFALPSKILPSVVLVPLHTTPKDVEKELNALYDVFLDVSQRWQNEDVILLGDFNADCASLTKKRLNSLLLRTEAGFHWVISDGEDTTVRASTNCTYDRIVMHGQGCQTLLRAAAPFNFPRSFQLTEEEALSISDHYPVEVELSQATHNIQLFSLAILLLLSLLPSQLS
What are the official names of this protein?
Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: FGF2_RAT
Sequence: MAAGSITSLPALPEDGGGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHVKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTEECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: PEPQ_ESCF3
Sequence: MESLASLYKNHIATLQKRARDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: RS17_AERS4
Sequence: MTDKIRTLQGRVISDKMEKSITVAIERKVKHPIYGKIIKRTTKLHVHDENNECKAGDLVEIRECRPLSKTKSWTLVAILEKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SYE_TREDE
Sequence: MQVKVRYAPSPTGFQHIGGVRTALFNYLFARSKGGKFVLRIEDTDRTRYSEEYEQNLYDTLEWLGLEWDEGGPKGGPCAPYIQSQRFDIYRKYAQELVDKGFAYYCFCDSERLDRIRKIQTMNKMPPGYDRACRNLTDEEIKAKMDEGIPYVIRLKVPLEGSTKFTDALLGDIEWKNEDINPDQILLKSDGFPTYHLANIVDDHLMGITHVMRAQEWLPSTPMHVIMYKAFGWEPPQFCHLPMVMGNDGQKLSKRHGATSCNEFRNKGYLKEAIINYVAMLGCSYEDGRDMYSLSDLEKLFDIKHLNKAPAVFDYKKLEWFNGQYMREKTDEELFALTWPYIANSGLFGKINEEELKKAGCRFENQTYLKPTQEQKEILMKVMPLVKERLHLLSEITEMVRFLFEEPAVPPAEEIIPKKLDAETTKKVLQKAIEVMPKILGLDDHAGGEVFRAEADAMGIKMGDFMMPVRMTVTGSRISPPLVGSIQILGIEKAIKRIEKAIAERF
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.