PharMolix/UniProtQA huggingface dataset:
Protein: MZRA_EDWI9
Sequence: MNQANSQPFTRRQGWKRILGLLLFIVAALTVVILPQLGHKEVSLQIRATHNGLATPDGFFVYQKLDENGVSITSITQDREGLVIRLAHPEQRTLALQVLQRELPPGYSIADKILHRSLFYKSERPAAATLSYSAGHNR
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL35_BRUMB
Sequence: MPKMKTKSAAKKRFKITGTGKVKAAAAGKRHGMIKRSNKFIRDARGTMVLADADAKIVKQFLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PSUG2_PHOLL
Sequence: MKNHAISNKYLDISPEVTEALENNRPVVALESTIIAHGMPYPQNVKTALQVEQKIRENGAVPATIAVINGMMKAGLSHEEIAFLARKGDEITKVSRRDLPFVIAAGKNGATTVASTMIIAAMAGIRIFATGGIGGVHRGAEQTFDISADLQELAKTSVAVVCAGAKSILDLGLTTEYLETHGVPLIGYQTHALPAFFCRTSPFSVNIRLDSPEQIAQAMAVKWDTGLQGGLVVANPIPEPYAMPEAEISAAIEQAVRESIEQRVNGKACTPFLLARVSELTGGNSLSSNIQLVLNNAELAAKIACCYWERHM
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase 2, PsiMP glycosidase 2.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: VIUA_VIBC3
Sequence: MAVLCPARVSVAENKKFKLHTLSAMMMGLFTGSFAYAETQNTSNQEQEMPVLVVIGEKTQRSIYETSASVEVFDQDTIERTPGATEIDDLLQLIPNLVDSGQSNNMPTIRGIDGSGPSVGGLASFAGTSPRLNMSIDGRSLTYSEIAFGPRSLWDMQQVEIYLGPQSYIQGRNTSAGAIVMKSNDPTHHFESAVKAGIGESDYSQTAGMISAPIIQDELAFRLSFDQQKRDSFVDLAAFEPAGDPKKIEMNSVRGKLLYEPSALDGFKTTLTLSHMDSRGPQTENINVAGNEAFRPVYETASFTTAWDIIWHLNDLFTFENNLVYADFSYDRYTNPNSRGDFNTDGKEFHIEPLLRYIALDGSVNTLIGARYYQSSQDDMYIDAASAYPMDGRTKAKSVFAEVTYALTPSINVNLAGRFEREQVKRNVSHPRYKLDYDETSSVFLPKLDVAYTPVQGQTYGIKAAKGYNASGAGLAFNSMQFTGFRPYEFEQESIWNYEFYTRHRFSHSVEVLTNLFYNDFDSMQMTQTTSSGDVFIANLDEASTYGAEIGSRWYATSSLELFANLGLLKTEFKETTGNTKELPRAPKMSANVGLLYDFGQGFEFSSNAAYTGSYFSESGNSEKFAIDSYWVANAQLAYVFEHGRATLYATNLLDSDKTTLYLSTNNTLDQLKQQPRMIGASVQLNF
What is the function of this protein?
Receptor for ferric vibriobactin.
What are the official names of this protein?
Vibriobactin receptor.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS5_ALIF1
Sequence: MAKEQQQATDLNEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKSMEKARRNMFTIALNEGTLHHAVKGRHTGSKVYMQPAAEGTGIIAGGAMRAVLEVVGVRNVLAKAYGSTNPINVVRATIAGLSSVKSPEMVAAKRGLTVESISE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ACKA_DESDA
Sequence: MKILVINAGSSSCKYQLLEMDTHAVLCSGLAERIGQDEGRLTHKIAPDTDKEEKIVQTAHFPTHVQAMEMVIALLTDAEKGVIKDKSEIAGIGHRVLHGGEAVSDPVLVDERVKGIVRECAVLGPLHNPANLMGIEVAEKLFPGVPNVAVFDTEFGMGMPKEAFMYALPYELYEDLRIRRYGFHGTSHKYIAGATAKYLGKPLSELRSITMHLGNGSSMSCVRNGKCFDTSMGLTPLEGLIMGTRCGSIDPAIVPFVMEKKGLTPEQVDTLMNKKSGLLGLCGHTDMRDVHAEVEKGNERAALALKMLVRSIKKTLGSYYFLLDGKVDALVFTAGIGENDDIVRAEVCAGLENLGIKIDAKENGTRKAGARAISTPDSSIPVLIIPTNEELQIAMATVEVLGK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOS_RHIME
Sequence: MQIENRLNAAAASGDGLGNLAGRSADPTGAADKGESGVPVPPTGFVDPTPRISLSADALLYLGRAKRTPEKLPPLTKDEWNNRLSPQLAAREHQAFGRLAETGDYRAYYRAFIDYYDGLRPEDQNSLRYFGTREAAVAGLRSLDYDADSGLDMDAEFENLVSVFLEEDKIAPSPATTTMSPAERAFFAWDASNISYEVDAPEPRPMTEIERLYSELL
What is the function of this protein?
May be part of a system that R. meliloti uses to respond to plant (alfalfa) biotin signals.
What are the official names of this protein?
Biotin transport regulator.
Protein: YCF12_GLOVI
Sequence: MAWRNPMNTLISLLLLTLIMLAGPAVIALWYFRGRQV
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: A1AT6_MOUSE
Sequence: MTTPFSSHGLLLLVGLCCLLLITKTKHEKLYEDPSIDPFQCRKVALTICNVSITLFKKMAQLSGNGNILFSPIRVIAAISMLSLGSNGNLSKHILETLRFNKTGLPEAEIHKCFWYLLHSIHQTEETSSLQTGSSVFIHQDLTSVDKFVKGVKELYHSDMISINFTDSSQAKTQINNYVMEISQKAIVNIVKNLESDTFLAVVNYIIWNAKLDSNFGCRSVKVKDYHLGYGMTIKVPMIHNMAMHYLFRVGDLSSTVLMLTLLTGNFATYFIIPDPGKMQKVEQSLTYPHFRRMRRQLLTRLVDLEIPELSLSETHDLESMMSLLGITYVFNSGTNSSDMNDTLQKSFKVVSKAVLTIDEKGSKPSTNSCFKKLGSTDMGRMQLNRPFLIFIQDHTNDVPLFLGRVVNPQN
What is the function of this protein?
Inhibitor of serine proteases.
What are the official names of this protein?
Alpha-1-antitrypsin 1-6, Alpha-1 protease inhibitor 6, Alpha-1-antiproteinase, Serine protease inhibitor 1-6, Serine protease inhibitor A1f, Serpin A1f.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_PHEZH
Sequence: MEKVPMTAEGYKALDEELKRLKTVERPAVIAAIAEARSHGDLSENAEYHAAKERQGWIEGQIAEIEDKMARAQVIDVSKLSGEQVKFGATVSLIDEDTEEEARYQIVGEHEADVKAGRVSVTSPIARAIIGKETGDVVEVNTPGGVKAYEITKVEWV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ULAE_ECOL5
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: FAC17_MYCBO
Sequence: MTPTHPTVTELLLPLSEIDDRGVYFEDSFTSWRDHIRHGAAIAAALRERLDPARPPHVGVLLQNTPFFSATLVAGALSGIVPVGLNPVRRGAALAGDIAKADCQLVLTGSGSAEVPADVEHINVDSPEWTDEVAAHRDTEVRFRSADLADLFMLIFTSGTSGDPKAVKCSHRKVAIAGVTITQRFSLGRDDVCYVSMPLFHSNAVLVGWAVAAACQGSMALRRKFSASQFLADVRRYGATYANYVGKPLSYVLATPELPDDADNPLRAVYGNEGVPGDIDRFGRRFGCVVMDGFGSTEGGVAITRTLDTPAGALGPLPGGIQIVDPDTGEPCPTGVVGELVNTAGPGGFEGYYNDEAAEAERMAGGVYHSGDLAYRDDAGYAYFAGRLGDWMRVDGENLGTAPIERVLMRYPDATEVAVYPVPDPVVGDQVMAALVLAPGTKFDADKFRAFLTEQPDLGHKQWPSYVRVSAGLPRTMTFKVIKRQLSAEGVACADPVWPIRR
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension.
What are the official names of this protein?
Medium/long-chain-fatty-acid--CoA ligase FadD17, FACL, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HEM2_ARCFU
Sequence: MAEFPKVRMRRLRKANLRWMFREARLSPENLITPIFVDENIKEKKPIESMPDYFRIPLEMVDKEVEECLEKDLRSFILFGIPSYKDETGSSAYDQNGVIQKAVRRIKAEFPDAVIVTDVCLCEYTTHGHCGVVKDGEIVNDETLPIIGKTAVSHAESGADIVAPSGMMDGMVKAIREALDAAGFESTPIMSYSAKYASNFYSPFRDAAESGFKFGDRRGYQMDIHNAREAMREIELDVKEGADIIMVKPALPYLDIIRMVRERFDLPLAAYNVSGEYSMIKAAIKNGWLSEEAIYEVLISIKRAGADLIITYHSKEIAEKLQ
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: PPAF3_HOLDI
Sequence: MWLSLVILGVASAIVNVSTQESCTTPNGETATCLPIESCKIFWDYVVTSGADPEINSFLRASLCRQGNYVVCCGSTLKFNSALPDRTECGLQDDFKVLGGEDTDLGEYPWMALLQQTKTSGAKSFGCGGSLISDRYVLTAAHCVVSSSYTVTMVRLGEWDLRATQDCVGSGSYQYCSPPPQDIGIESITSHPNYEKSSRGVFNDIALIRLARPVNRNKYVQPICLPLPTERTPVGENLLVAGWGATETKAQSDKKQKLKLPVTDLPACKTLYAKHNKIINDKMICAGGLKGKDSCKGDSGGPLFGQTGAGNAQFYIEGIVSYGAICGTEGFPAIYTRVSDHLDWIKQNVRV
What is the function of this protein?
Serine endopeptidase which, by cleaving prophenoloxidase activating factor PPAF2, is required for the activation of the prophenoloxidase cascade probably following the recognition of pathogen-derived products.
What are the official names of this protein?
Phenoloxidase-activating factor 3, Prophenoloxidase-activating factor III, Serine protease-like protein PPAF-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: SLX4_SCHPO
Sequence: MSAEEYIEVSSSPDIFTDDDDMITIEPELNKNPKDCNSKRKRSVTECCEIRLITSKCDFESTQQLVHHNCTGHKVHEHNLNAVDEEDFDTENLPLLFSSFSDNESDILEPDLNTRVAEDNDVLLSRYSKIKNSASCRNTFEHSAYHSNREEISSSGFYYHRKPQLFEKSLEKLGNKSIEANRSPLIKELCESANSTENVCFSVSTVDEIQQRHPSAGHSIDSTCQSNSFLEGDSATHKKKKTDNIKEFTSCEFNDRSRTLLNYAGYMDTNKNADNEAKSLKEKLENFPVEKLRAIAESYGFKSSDSKATLIKIVESCLDAIDSRSQSKKLGKETPHDYLITSTKTVLEFDDIVTQTHRAISQVVKQAKDNSVWIKILTYSAIDVEEFQLWLKRKNLNVSLDLIKSWCDKYGVLMKGSWH
What is the function of this protein?
Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for stem-loop (SL) and splayed arm Y structures.  Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction.  Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks.  The complex initiates homologous recombination (HR) events, used to maintain rDNA copy number, in the rDNA repeats that are processed by a mechanism that requires rad22, but not rhp51.  Has Holliday junction resolvase activity in vitro.  Slx4 is required for efficient processing of DNA substrates.
What are the official names of this protein?
Structure-specific endonuclease subunit slx4, Synthetic lethal of unknown function protein 4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Associates with chromatin at rDNA repeat protrusions.
Protein: RCF1_PICST
Sequence: MVIRSKEQPVVPLGALATTGAIILAARSMKRGEKLRTQVYFRYRVVFQLITLVALVAGGVMMQQESAEQKKTREDKLREKAKQREKLWIEELERRDALIQERKRRLEESRAELKKMAEEGFKQENDNSKGK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: METK_ACET2
Sequence: MARKLFTSESVTEGHPDKICDQISDAVLDAIFSQDPMARVACETAVTTGLVLVTGEITTNCYVDIPKIVRSTIREIGYDRAKYGFDCDTCAVLTSIDEQSPDIAMGVNKALEAKTGEMSDEEIEAIGAGDQGMMFGFACDETPELMPMPISLAHKLAMRLSQVRKNGTLNYLRPDGKSQVTVEYDGDKPVRVDTVLISTQHGPEVDYDTIKRDVIEHVIKPVIPAELLDSKTKYLVNPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLARKCEVQLAYAIGVARPVSVRVDTFGTGIIPEEKIESLVNKYFDLRPAGIIKTLDLRRPIYKQTAAYGHFGRTDIDLPWERTDKAEELRKEAQSL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_VIBC3
Sequence: MITKLLTKVIGSRNDRTLRRLRKIVKEINNYEPAFEALSDEELKAKTVEFRQRIEQGENLDQLLPEAFATVREASKRVFGMRHFDVQLIGGMVLHGGQIAEMRTGEGKTLTATLAAYLNALPGKGVHIVTVNDYLAKRDAETNRPLFEFLGMTVGVNIPNMPQPAKKEAYQADILYGTNNEFGFDYLRDNMAFRPEDRVQRARFFAVVDEVDSILIDEARTPLIISGPAEDSSDLYIRINKLIPLLQKQDKEDSEEYRGDGHFTVDEKSKQVHLTETGQEFVEELLVKNGMMQEGDTLYSPANISLLHHVNAALRAHVLFEKNVDYIVTPDGEVVIVDEHTGRTMPGRRWSDGLHQAVEAKEGVKIQNENQTLASITFQNYFRLYEKLSGMTGTADTEAFEFQQIYGLETVVIPTNKPMVRNDMPDVVYRSEAEKFAAIIEDIKQRVEKGQPVLVGTVSIEKSELLSNALKKAGIKHNVLNAKFHEKEAEIVAEAGKPGAVTIATNMAGRGTDIVLGGSWQAKVEKLDNPTQEQIDAIKAEWKQVHDQVLQAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDTLLRIFTSDRMAALIQSGMDEGEAIESKMLSRSIEKAQRKVEGRNFDIRKQLLEYDDVANDQRKVVYELRDELMSADDISDMIAQNREDVLNAVMDEYIPPQSLEDMWDIKGLEDRLKNDFDLPLPIQSWLDADNKLYEEALRERIIEQAVEVYKAKEQAVSPAVMRNFEKSVMLQTLDTLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEDLLESLKSDVITVLSKVRVQQQEEVERMEAQRRAQAEEAARHAQAQHASADDAEQDESNQPMVRDERKVGRNEPCPCGSGKKYKQCHGQIN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MURE_LIMRD
Sequence: MELHITPALALLREHHLLDHVSNLTDFTATSVSYDSRKVKSGTLFFCKGNFLPKYLASAKEKGAIAYVAEKEYPEGEGLPAIIVNDEQKAMSLLGAAFYGYPQNDLFIIAITGTKGKTTTAYFADHILAQSTADHIALFSTLDRILGNKPEDKFKSDLTTPESLDLFHDMRVAVDNGMTHLVMEVSSQAYKKNRIYGLKYDVGIFLNISPDHIGRNEHPTFADYLHCKEQLLVNSAKCLINAETEKFTDVYYTAKATTQPEDIFLFARRGANIELPDNAQIDFEYRNDLEDLHESEFELTALTEKAKQLNLDGRYKTSVPGDYNEGNAVAAIIASGLAGASANDAVETLNHVHIRGRMEMINSNTHGTIYVDYAHNYASLKRLLAFLKRQTNAGKVTVVLGATGDKGISRRPGFGKALTEEQPDEVILTTDDPGFEDPMTIAREIDSYIDHDKVKHIQFEMDRETAIKKAIDGSENDDIVVLAGKGEDPYQKVNGEDVPYPTDVKIARDYINELER
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMW_BUCAP
Sequence: MFKLPPISLYIHIPWCIKKCGYCDFYSYVNKSFIPEKEYIDHLLKDLEKDLSLIKEREINSIFIGGGTPSLLKSSSIKKMMREIKKRINISNTAEITIEANPTTLEYKRFFNYKKSGINRFSIGVQTFNSDLLKKIERTYNKREAILAVEEIKKINKNFNLDIMYGLPNQSLKDVLLDLQYAVKYNPTHISWYQLTLEPNTPFYVKKLNLPNENNIFKMLVEGEKFLKQSGYKKYEISSYAKLNYECQHNLNYWNFGDYIGIGCSAHGKITQINGDIIRTIKNKNINDFMNGKYLKHKNFVLKKDKPFEYFMNIFRLYKPVLKRQFEERTNINQNYIKEKIKKAIEKGYLKNKIDFWDTTKKGKMFLNSLLKIFLD
What is the function of this protein?
Probably acts as a heme chaperone, transferring heme to an unknown acceptor.  Binds one molecule of heme per monomer, possibly covalently (By similarity).  Binds 1 [4Fe-4S] cluster.  The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity).
What are the official names of this protein?
Heme chaperone HemW, Oxygen-independent coproporphyrinogen-III oxidase-like protein BUsg_532.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1155_BACAN
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMGIMKTATSNMHMWYGLKMIAGILVIGGMEMVLVKMSKNKATGAVWGLFIVALVAVFYLGLKLPIGWQVF
What are the official names of this protein?
UPF0344 protein BA_1155/GBAA_1155/BAS1072.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THI21_YEAST
Sequence: MTYSTVNINTPPPYLALASNEKLPTVLSIAGTDPSGGAGVEADVKTITAHRCYAMTCITALNAQTPVKVYSINNTPKEVVSQILDANLQDMKCDVIKTGMLTTAAIEVLHEKLLQLGENRPKLVVDPVLVATSGSSLAGKDIASLITEKIAPFADILTPNIPECFKLLGEDREISKLRDIFEVAKDLAKITKCSNILVKGGHIPWNDEEGKYITDVLYLGAEQRFITFKGNFVNTTHTHGTGCTLASAIASNLARGYSLPQSVYGGIEYVQNAVAIGCDVTKETVKDNGPINHVYAIEIPLEKMLSDECFTASDAVHKKPVKSSLNKIPGGSFYKYLINHPKVKPHWDSYVNHDFVRKVADGSLEPKKFQFFIEQDYLYLVNYARISCIAGSKSPCLEDLEKELVIVECVRNGLCQHERRLREEFGIKDPDYLQKIQRGPALRAYCRYFNDVSRRGNWQELVIALNPCLMGYVHALTKIKDEVTAAEGSVYREWCETYSSSWCHEAMLEGEKLLNHILETYPPEKLDTLVTIYAEVCELEANFWTAALEYE
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and also probably that of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thiaminase-2 family.
Protein: CCA_CITK8
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTREEYALARTERKSGSGYTGFTCYAAPDVTLEEDLQRRDLTINALAQDDDGHIVDPYQGRRDLDNRLLRHVSPAFSEDPLRVLRVARFAARYAHLSFRIADETLALMRDMTAAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEVDALFGVPAPAKWHPEIDTGIHTLMTLSMAAMLSPNVDVRFATLCHDLGKGLTPKALWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLAKLVAEFHDLIHTFPILQPKTIVKLFDSIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWLVAQAVPTKEVVEAGFKGAEIREELTRRRIAAVANWKERRCPKPEA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: UBIA_SALCH
Sequence: MEWSLTQSKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGMPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTVNRPLPSGAVTEKEARNLFVVLVLLAFLLVLTLNAMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDIKIGIKSTAILFGRYDTLIIGILQLGVMALMALIGWLNGLGGGYYWAVLVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCME_ESCF3
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: NR1AB_DANRE
Sequence: MLRLWPGGAPGGLASILLRISLRLALWLPPLTLGSALAEGPGELYVPQHMPHHLVPAARSHAPLRAGHAGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSGLGDYLQLQIERGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNIDNERLAIARQRIPYRLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYNGLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSSVSAAGNRSETSPSITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSGGLAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSATQPNGAAVKEKPIGVPKNKKDKKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May play a role in formation or maintenance of synaptic junctions.
What are the official names of this protein?
Neurexin-1a-beta, Neurexin Ia-beta.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RBSD_ECODH
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_FRATT
Sequence: MTWSDILAEEKQKPYFKQILDFLACESAKGKVIFPTKENIFNAFKYTELDNLKVVILGQDPYHNYNQAHGLAFSVQKGVDIPPSLQNIYKELARSIPEFKTPNHGYLVDWAKQGVFLLNTTLTVEAHKANSHKDIGWETFTDTVINKISENKHNVVFMLWGSHARKKKVLIDSSRHLILESTHPSPLSAHRGFLGCNHFVDCNKYLIEKKDQKIDWNLLC
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.