PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_THEP1
Sequence: MFITFEGIDGSGKSTQIKLLARYLEKRGKRVILKREPGGTETGEKIRKLLLKEEMTPKAELFLFLASRNLLVMEIKRYLSEGYVVLLDRYTDSSVAYQGFGRNLGKEIVEKLNDFATDSLVPDLTFYIDVDVETALNRKGELNRFEKREFLERVREGYLVLAKEHPERIVVLDGKRSIEEIHRDVVREVERRWKLDV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TGT_STRS2
Sequence: MTDVPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTMSPEELKAMGSGIILSNTYHLWLRPGDELVARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNISEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFPGYSIGGLAVGETHDEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTNRGRLVVKNAQFAEDFTPLDPECDCYTCKNYTRAYLRHLLKADETFGIRLTSYHNLYFLINLMKNVRQAIMDDNLLEFRQDFMEKYGYGKNGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: WASC5_DICDI
Sequence: MVKEFLGEGSQAGQNLLRLVSRGNAIIAELLRLSAHIPSVFKLEDRNEARKYQDILLDFKYLSNPDFYESKIEENADLVDLETEFRDNHIDILIRFYHLFESIYKYIMDLEHYIVDVEKGFYIHLTIEAILINGDGKQLLSEAVYLYGVMLILMDNLIEGPVRERMLISYLRNKGPVDLPLIDEVCKLCKSTGYIPGSPKKPPNYPEEYFRRVELPENVISMIVGRLRSDDLYNGTESFPQPEHRSVALSTQACMIYVILYFIPDILNNKNSIMREIVDKFFPDNWVISFFLGFTIDLSVAWEPYKAAKTAMGNTIIQSNIQYQTQRFWKEVSELNKLVDDLLVDGLLVEEYIVDNVHKIITTLRRCNVTIRWVMLHSNASQKKFKDLVLMGGSQEDVLYLLLNTAQLEFVFKNIFQQLLATKEEKWEENKKLASDSMVELSEYFSGEKALTRVKKNENLQKWFGEISQKISQLDSTDSTSTGRKIQQLSLALEEVEQFQQIDSSIQVKQFLIETRQFLTKMIKIVNIKEEVLVNLSVCADMSYAWEIVNNYVDQMQKGIKSDPKCVLKLRATFLKLVSILDLPLVRIAQCSSPDLISVSEYYSGELVGYVRKVLEIVPKQMFLILKQIINMQTNNIQEMPTKVEKERLRDFAQLDQRYDLARATHSVSVFTEGILAMETTLVGIIEVDPKQLLEDGIRKELVLQIALAMDKTLIFSGKPYQAPSNKQQQQEIELLQRLKELSNILDGFRRSFQYIQDYVNIQGLKIWQEEFSRIVNFYVEQECNSFLKKKVYDWQSQYQSVAIPIPKFPSQSDQNSQQSVNMIGRLARELLNQTNCKTTLYLNQIGWFDPSSGKELVGINTWSILHQSVGIFGLTGLDKLFSFMMVKDLQVFVSQTRSLVEKSLKGFLNEFEDYLRPTTNIPDTMIRYQQALDKTKLLYPIFIDVLTKIGQIQLIRRQISNQLNFHCKIDSNMLFSSLDIMNKSLLNDIESHFQRPDSNPYPSDDNTLLFDLAQYLDTAGINDPFTKIYITTSPLEQFPCLLFLFVLSQVSKFQFNSKLNVMSSKKQKNSYDWTPFIIGCITILQQFHSLHTQKFLAFVGQYIKSHINIALANPKENNKDDADYPEDVIGLLRFLEDFCKYSHTSRKIVEGYVPPYIFDYYNN
What are the official names of this protein?
WASH complex subunit 5, WASH complex subunit strumpellin homolog.
What is the protein family that this protein belongs to?
Belongs to the strumpellin family.
Protein: NU4LC_MAIZE
Sequence: MMFERVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS20_DESVV
Sequence: MANHKSALKRHKQSLKRAARNRAVRTRIKNVIKDVRIALQQQDKEQAATALVQASAVLDKAASKGVVHWKTAARKISRLTKAVNQVA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NUOC_BURVG
Sequence: MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGIDYQTYGDGAYDGPRFAAVSQLLSVTNNWRLRLRVFAPDDDLPIVPSLVDTWSSSNWYEREAFDLYGLVFEGHPDLRRLLTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CDGT_BACLI
Sequence: MFQMAKRVLLSTTLTFSLLAGSALPFLPASAIYADADTAVTNKQNFSTDVIYQVFTDRFLDGNPSNNPTGAAFDGTCSNLKLYCGGDWQGLVNKINDNYFSDLGVTALWISQPVENIFATINYSGVTNTAYHGYWARDFKKTNPYFGTMTDFQNLVTTAHAKGIKIIIDFAPNHTSPAMETDTSFAENGKLYDNGNLVGGYTNDTNGYFHHNGGSDFSTLENGIYKNLYDLADLNHNNSTIDTYFKDAIKLWLDMGVDGIRVDAVKHMPQGWQKNWMSSIYAHKPVFTFGEWFLGSAAPDADNTDFANESGMSLLDFRFNSAVRNVFRDNTSNMYALDSMLTATAADYNQVNDQVTFIDNHDMDRFKTSAVNNRRLEQALAFTLTSRGVPAIYYGTEQYLTGNGDPDNRGKMPSFSKSTTAFNVISKLAPLRKSNPAIAYGSTQQRWINNDVYIYERKFGKSVAVVAVNRNLTTPTSITNLNTSLPSGTYTDVLGGVLNGNNITSSGGNISSFTLAAGATAVWQYTASETTPTIGHVGPVMGKPGNVVTIDGRGFGSAKGTVYFGTTAVTGSAITSWEDTQIKVTIPPVAGGDYAVKVAANGVNSNAYNDFTILSGDQVSVRFVINNATTALGENIYLTGNVSELGNWTTGAASIGPAFNQVIHAYPTWYYDVSVPAGKQLEFKFFKKNGATITWEGGSNHTFTTPTSGTATVTINWQ
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_POLSJ
Sequence: MTQPTVTADDPDLSHVGPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVLLKLVGMNPVVVHGGGPQIEAALNRLGKKGHFIQGMRVTDEETMEVVEWVLAGQVQQDIVGLINQAGGKAVGLTGRDGGLIRAQKLKMVDKDDPAKEHDIGFVGDIVSIDPSVVKALQDDAFIPVISPIGFGESNESYNINADVVAGKLATVLKAEKLVLLTNTPGVLNKAGELLTDLTAREIDDLFADGTISGGMLPKIEGALDAAKSGVNSVHIIDGRVPHAMLLEILTDQAYGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_AHSV4
Sequence: MQGNERIQDKNEKEKAYAPYLDGASVSTDNGPILSVFALQEIMQKIRQNQSDMAAHAPDVDGAIPEVMTIISGIKGLLEEKDYKVINAPPNSFRTIPMQSTEYVLQVNTFYERMSEIGGPIDETDPIGFYALILEKLKFLKSEGAFILQGIATKDYRGAEIADPEIIGVSFQNALSHLAAIDRQIIQDTLNGMIIENGLVADRNVDVFRAAMSDPIYRIHNVLQGYIEGIQYGELRESVNWLMRLGLRKRIEFANDFLTDFRRADTIWIISQRLPINANVIWNVPRCHIANLITNVALCLPTGEYLMPNPRINSITITQRITQTNPFSIISGLTPTAVQMNDVRKIYLALMFPNQIILDIKPDSSHAVDPVLRMVAGVLGHVMFTYGPIMTNITPTMAELLDRALSDYLLYMYNNRIPINYGPTGQPLDFRIGARNQYDCNAFRADPQTGRGYNGWGVVDVQRVQPSPYDHVQRVIRYCDIDSREIIDPRTYGMNMTYPIFREMLRMLVAAGKDQEAAYLRQMLPFHMIRFARINQIINEDLLSAFSLPDQNFDVVLHNFIQGNFGETDPVVLEVSWASIWFAFVRRFEPIARSDLLEAAPLIEARYAAELSTMQMDVQQLRMMRARVPDTVINATPSQCWKAVLKNAPEPIKNLMNLSHSFSFVNVRDIVRWSQQRDIQESLAYVLNREAWAIANDFEDLMLVDHVYIQRTMLPEPRLDDINEFRRQGFFYTNMIDGAPPIGDVTHYTYAIANLQANMGQFRAAIRRTLDDNGWIQFGGMLRNIKIKFFDSRPPDEILTAMPYVYTEEERDGVRMVAFKYATTATAYFLLYNVAYSNTPDTLITVNPTFTMTKIHMRKKIVRRVRAPDVVSQVNKRLVAYKGKMRLMDVTKCLKTGVQLARPTI
What is the function of this protein?
The VP3 protein is one of the five proteins (with VP1, VP4, VP6 and VP7) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP3 family.
What are the subcellular locations of this protein?
Virion.
Protein: DCPS_ASCSU
Sequence: MVDEVDANSTGDNSLVNMKGFSFKEVLGSDSARKSAFILLDSSNGENAILLADKNAFPVDKTSWSAILTGSTLKPIMKNDIYSSYTLCMPNEFSDVKSTLIYPCNEKHIAKYRDQKRFIINETPEDYRTITLPYIQRNQMSLEWVYNILDHKAEVDRIIYEETDPHDGFILAPDLKWSGEQLECLYVQALVRRKGIKSIRDLTANDLPLLEGIRDKGLNAIKEKYGLDKHQIRAYFHYQPSFYHLHVHFIHVSYEAPASGVAKAVLLDDVINNLKLIPDFYQRSTLTFTAKEQDPIYRREN
What is the function of this protein?
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs of the 3'->5' exosome-mediated mRNA decay pathway.  Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) and tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with up to 2 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP).  Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules.  Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) and tri-methylguanosine diphosphate (m3(2,2,7)GDP) to m(7)GMP and m3(2,2,7)GMP, respectively (PubMed:15383679, PubMed:22985415).  May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by dcs-1 to m7GMP.  Binds to m7GpppG and strongly to m7GDP.
What are the official names of this protein?
m7GpppX diphosphatase, Decapping scavenger enzyme, Scavenger mRNA-decapping enzyme DcpS.
What is the protein family that this protein belongs to?
Belongs to the HIT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCAFD_BPS13
Sequence: MSQVTEQSVRFQTALASIKLIQASAVLDLTEDDFDFLTSNKVWIATDRSRARRCVEACVYGTLDFVGYPRFPAPVEFIAAVIAYYVHPVNIQTACLIMEGAEFTENIINGVERPVKAAELFAFTLRVRAGNTDVLTDAEENVRQKLRAEGVM
What is the function of this protein?
Assembles the procapsid by joining twelve 12S pre-assembly complex into a T=1 icosahedral particle, called 108S procapsid.  Ten proteins D bind each 12S complex, which are formed by three pentamers of F, G, B protein and a H protein.  The scaffolding protein is released from the provirion after genome packaging to form the mature virion.
What are the official names of this protein?
External scaffolding protein D, Scaffolding protein D, GPD.
What is the protein family that this protein belongs to?
Belongs to the microvirus D protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: HNS_SERMA
Sequence: MSERLKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEDSQAQAEIEERTRKLQQYREMLIADGIDPNELLQTMAANKAAGKAKRARRPAKYQYKDENGELKTWTGQGRTPAVIKKAIEEQGKSLDDFLL
What is the function of this protein?
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction.  Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome.  As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes.  A subset of genes are repressed by H-NS in association with other proteins (By similarity).
What are the official names of this protein?
DNA-binding protein H-NS, Histone-like protein HLP-II.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NADD_THET2
Sequence: MRIGLFGGSFDPIHLGHLLAASQAQEVLCLDRVLFVVAARPPHKVPVAPAEARYEMTLLAVAEDPRFTVSRLELDRPGPSYTVDTLRKARRLFPQDELFFITGADAYRDVLTWKEGERLPEYATLVAVARPGYPLEEAPLPVVPLFVPEVGISSTEIRRRLKEGRSVRYWVPRAVEVYIEKHGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y3012_BORA1
Sequence: MTAIFRSASADDARFTDFSNQFLMAMPGMVNDELAGTVIYICEHTPRGALGLVLNRPTDLTLASLFERIDLTVAMGPTADEKVFFGGPVQTDRGFVLHAPAGDYSSSIRLGDLALTTSRDVLQAVAEGQGPARLFVTLGYAGWGAGQLESEMSQNAWLSVAADPVIIFDVPAEERYPAAMRLLGIDPLMLAGEAGHA
What are the official names of this protein?
UPF0301 protein BAV3012.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DTX_DROME
Sequence: MASSAGSAASGSVVPGGGGSAASSCATMALSTAGSGGPPVNHAHAVCVWEFESRGKWLPYSPAVSQHLERAHAKKLTRVMLSDADPSLEQYYVNVRTMTQESEAETAGSGLLTIGVRRMFYAPSSPAGKGTKWEWSGGSADSNNDWRPYNMHVQCIIEDAWARGEQTLDLCNTHIGLPYTINFCNLTQLRQPSGPMRSIRRTQQAPYPLVKLTPQQANQLKSNSASVSSQYNTLPKLGDTKSLHRVPMTRQQHPLPTSHQVQQQQHQHQHQQQQQQQHHHQHQQQQHQQQQQHQMQHHQIHHQTAPRKPPKKHSEISTTNLRQILNNLNIFSSSTKHQSNMSTAASASSSSSSASLHHANHLSHAHFSHAKNMLTASMNSHHSRCSEGSLQSQRSSRMGSHRSRSRTRTSDTDTNSVKSHRRRPSVDTVSTYLSHESKESLRSRNFAISVNDLLDCSLGSDEVFVPSLPPSSLGERAPVPPPLPLHPRQQQQQQQQQQQLQMQQQQQAQQQQQQSIAGSIVGVDPASDMISRFVKVVEPPLWPNAQPCPMCMEELVHSAQNPAISLSRCQHLMHLQCLNGMIIAQQNEMNKNLFIECPVCGIVYGEKVGNQPIGSMSWSIISKNLPGHEGQNTIQIVYDIASGLQTEEHPHPGRAFFAVGFPRICYLPDCPLGRKVLRFLKIAFDRRLLFSIGRSVTTGREDVVIWNSVDHKTQFNMFPDPTYLQRTMQQLVHLGVTD
What is the function of this protein?
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.  Mainly acts as a positive regulator of Notch, but it may also act as a negative regulator, depending on the developmental and cell context.  Mediates the antineural activity of Notch.  May function as a ubiquitin ligase protein in the Notch pathway.
What are the official names of this protein?
Protein deltex, Probable E3 ubiquitin-protein ligase deltex, RING-type E3 ubiquitin transferase deltex.
What is the protein family that this protein belongs to?
Belongs to the Deltex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CLOBK
Sequence: MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPLRDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TR143_RAT
Sequence: MPSTPTLIFIVIFFLVSVASMLQNGFMIIVLGREWMRNRALPAVDMIVASLASSRFCLHGIAILNNFLASFDFCYQANFVGILWDFINTLILWLTAWLAIFYCVKISSFSHPVLFWLKWRISQLVPRLLLVSLIMGGLSAIISATGNIIANQMIISQGFHGNCTFGHMSLDFYRYYYLSHAVLMWFTPFFLFLVSIIFLMFSLYRHVEKMRGHRPGPWDPRTQAHTMALKSLTVFITFYILFFLALIISSTKSKTMHSYWYWVREIIIYTGIFLNSIILVLSNPKLRKALKMRF
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 143, T2R143, Taste receptor type 2 member 27, T2R27.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MMM1_AJEDR
Sequence: MADQTQPPPPVLTQPSLSFTQGLLVGQLSVVLLIGAFIKFFIFGEAPPHPSRNGLSNRTSSHRRSYSLNSISADSSPRTLREKPSTSNILRPVPSSSTNTRSILRKTYYSATPTNPTSKHSRSRPHHSSHQPESLDWFNVLIAQTIAQYRQTAYILKDSPTSSILASLSEALNNPEKKPSFIDSIKVTDISLGEEFPIFSNCRVIAVEDPNSDGGRLQALMDVDLSDDNLSLAVETSLLLNYPKPFSAVLPVALAVSVVRFSGTLCISFVPGPGTSDQTMSPSPSPPKEASAENIAVDHQSPERQSARQRAPHQHKYTNTNTAGATAAATADDNDTHAKLPHGIPKTSLAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARVQAWFEERVVEPRVQVVGLPNIWPRMGRTGVRGSQEETEAGAGGSAPADIPGTAGGDGVGVRGGGGGGGVGGSGGGSMRGTSGWGMGYDGLRYRHNAHGDGGVGAGPGQSAGAALYGGAQGGGGGGGRGGEEQFAIPGSMPDPVVVT
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: HIS6_MYCTO
Sequence: MYADRDLPGAGGLAVRVIPCLDVDDGRVVKGVNFENLRDAGDPVELAAVYDAEGADELTFLDVTASSSGRATMLEVVRRTAEQVFIPLTVGGGVRTVADVDSLLRAGADKVAVNTAAIACPDLLADMARQFGSQCIVLSVDARTVPVGSAPTPSGWEVTTHGGRRGTGMDAVQWAARGADLGVGEILLNSMDADGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAVAAGADAVLAASVFHFRELTIGQVKAALAAEGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E41_ADES1
Sequence: MGDNYWIDPVNLSPQELVETLQRIDQEGYEVIVVTEGGFPMGPFRMAFRIDEEPNMYYISQKDLALEYDPLQFLHWVRQYSGEIINWTHHGRVPWWKIFQMLEAKLEDSYYYETTMFYIPSSISHDCWSLFLQFWREGFGSPPLDVAWS
What are the official names of this protein?
Protein E4.1.
Protein: HIS7_RHOP5
Sequence: MRKATITRKTKETAIEVAVDLDGTGVSQVATGIGFFDHMLDLLARHSRIDIKVKADGDLHVDYHHTVEDVGIALGQAVKQALGSMAGITRYASLYMPMDETLTRVAIDISGRPALVFKAEFPRDKIGEFDTELVREWFNAFAGNAGITLHVETLYGENSHHIAESCFKGLARALRAAVAIDPRAAGEVPSTKGQLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5758_ARATH
Sequence: MSASYVSDLHINVKGVPFHLCKEMLAKRSSKVSSLLERNEIDELRLILRDLEVDPETFELVARFCNGSEFKFTSDTIVSVLCIAYYLGMNEEQSSNNLLGKASEFLEHRVFPSWSETINALRSGDKSFDKLADVGLVDVFFDSLIEKASYDPRLLGELIKNRAETDDYRPNPRRRLFVIDWKSEDLITIPLRLYEPFMIRAIKSRSIPVEYIVLSVCKYAKKWVFDTEESLSGQKREAIEVVERLLPYQRGLISCELLFESLKHSIWLEASSECQNGFMIRICKQLDMAKSTDLKILSRGYGEKAEGFENIELVKTVVKSFYTYYANEDSETVSHFVKVAKLSEEFLFLAASEASLKLEAFVELAEMTVAVSQGILSYSDGIYRAIDVFLESHRYLTESEKMEVCKVLECGKLSQEGFERAAKNQKLPLRIVVNVLCVSQLQIRDTVAKEIKGMEEKVDEEEEEEIEVSSDEDEMEKMSNKLLGLEIENDECVVHRRKNMKKKKKKISVWGQVKRKFGCLNSSSSSYSVDACTCDVKKKKKKIHHHYE
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At5g17580.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: RR4_PATFR
Sequence: RFKKIRRLGALPGLTSKRPRSGNDLKNQLRSVKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKVKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPQDIITTKDKQRSKALIQNYIASSTQPQEELPNHLTIDAFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TAUB_BURPS
Sequence: MAKLCAQQVSVVYASRRGALTALENVSMSVGSGEIVVALGASGCGKSTLLSLLAGFQPPTSGRVSVDGVPVAGPGADRGVVFQDDALMPWLNVIENVAFGLRMQGVGRDARHARARDVLRLVKLAGFEQHRIDEISGGMRQRVGLARALAADPSFLLMDEPLGALDALTREHMQTLLLDVWRATGKGVFLITHSVEEAVLLATELLILSPRPGRIVARHALDFARRYAHGEPVRSIKSDPRFTEIHLALVEQLMRETEEV
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TX9AN_BUNCN
Sequence: NIIDVPCRPCYYRDSSGNCVYDQLGCGA
What is the function of this protein?
Possible voltage-gated potassium channel (Kv) blocker.  Increases amplitude and duration of crab leg nerve compound action potential.
What are the official names of this protein?
Toxin Bcg III 23.41, Bcg 23.41, AnmTX BC 9a-1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone structural class 9a family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RL62_ARATH
Sequence: MPAKQRTAKVNRNPDLIRGVGKYSRSQMYHKRGLWAIKAKNGGVFPRHDAKSKVDAPVEKPPKFYPAEDVKKPLPNRRTAKPAKLRASITPGTVLIILAGRFKGKRVVFLKQLASGLLLVTGPFKINGVPLRRVNQAYVIGTSTKVDISGVTLDKFDDKYFGKVAEKKKKKTEGEFFEAEKEEKKEIPQGKKDDQKAVDAALIKAIEAVPELKTYLGARFSLKQGMKPHELVF
What are the official names of this protein?
60S ribosomal protein L6-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL6 family.