PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_CAMVC
Sequence: MAESILDRTINRFWYNLGEDCLSESQFDLMIRLMEESLDGDQIIDLTSLPSDNLQVEQVMTTTDDSISEESEFLLAIGEISEDESDSGEEPEFEQVRMDRTGGTEIPKEEDGEGPSRYNERKRKTPEDRYFPTQPKTIPGQKQTSMGMLNIDCQINRRTLIDDWAAEIGLIVKTNREDYLDPETILLLMEHKTSGIAKELIRNTRWNRTTGDIIEQVINAMYTMFLGLNYSDNKVAEKIDEQEKAKIRMTKLQLFDICYLEEFTCDYEKNMYKTEMADFPGYINQYLSKIPIIGEKALTRFRHEANGTSIYSLGFAAKIVKEELSKICDLSKKQKKLKKFNKKCCSIGEASVEYGGKKTSKKKYHKRYKKRYKVYKPYKKKKKFRSGKYFKPKEKKGSKRKYCPKGKKDCRCWICNIEGHYANECPNRQSSEKAHILQQAENLGLQPVEEPYEGVQEVFILEYKEEEEETSTEESDDESSTSEDSDSD
What is the function of this protein?
Self assembles to form an icosahedral capsid, about 50 nm in diameter, nm, composed of 420 subunits of the viral capsid protein.  The capsid encapsulates the genomic dsDNA.  Following virus entry into host cell, provides nuclear import of the viral genome.  Virus particles do not enter the nucleus, but dock at the nuclear membrane through the interaction with host importins (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: IF2_SACD2
Sequence: MAEVTVSELAKSVGAPVERILSQMQQAGLTHQSPDDVVSDEEKQKLLTFLKSSHGETVAEPKKITLKRKTTTTLKTGSGSGRKTVNVEVRKKRTYVKRDEVADEIEESAAVAEAEVAKVEEPVVEPVQEPEVAAEPEVVEAPEPEPVVEAIEEAPVEEPAAPAAPVISQTTTASSLVDDAEEMRIRAASARIKAEEERLAAIEKARKEKAAKPAPAPGPAAAAKEDARPTKHVEDLAKLKKPHDKKDEEFDEDGKKHNKKAGKAVKKVAGPKKVASALDYVEDKEEIEEVIHAPKPKRLSANRGPRPVIKVSNKHGFKKPTGKITYDVEIPETITVGELAQRMNVKAGEVVKCLMKMGTMATVNQPIDQETAQLVVEELGHKAVLISADAIEIKLQEEVAANVDGETIPRAPIVTVMGHVDHGKTSLLDYIRKAKVASGEAGGITQHIGAYRVQTSHGELTFLDTPGHAAFTAMRARGAQCTDVVILVVAADDGVMPQTEEAVQHARAAGVPLVVAINKMDKESADPDRVKNELSAKEVIPEDWGGDTQFIEVSAHTGQGIEELLEAVALQAELLELSAPKDVPARGVVVESRMDKGRGVVATVLVQGGDLKSGDILLAGQSFGRVRAMTNEFGEQVKTAGPSSPVEILGLDTPPQAGDEFLVVPDERKAREVAEFRAERERQEKLQRQQAAKLENMFAGIGENETKVLSVVLKTDVRGSLEAIQAALLDIGNDEVQVNIVGGGVGGITGNDVNLALTTGAIVLGFNVRADASARKLAETESIEIRYYSIIYQLIDEVKSALSGMLDPERVEEIVGIAEVRETFRSPKFGQVAGCMVVEGSVHRNKPIRVLRENVVIFEGELESLRRFKDDVSEVRNGTECGIGVKNYDVKVGDQIEVFDVKEVAREL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABEC1_RAT
Sequence: MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSIWRHTSQNTNKHVEVNFIEKFTTERYFCPNTRCSITWFLSWSPCGECSRAITEFLSRYPHVTLFIYIARLYHHADPRNRQGLRDLISSGVTIQIMTEQESGYCWRNFVNYSPSNEAHWPRYPHLWVRLYVLELYCIILGLPPCLNILRRKQPQLTFFTIALQSCHYQRLPPHILWATGLK
What is the function of this protein?
Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs.  Form complexes with cofactors that confer differential editing activity and selectivity.  Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA (PubMed:8511591).  Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA (By similarity).  May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (By similarity).
What are the official names of this protein?
C->U-editing enzyme APOBEC-1, Apo B messenger RNA-editing protein, REPR, Apolipoprotein B mRNA-editing enzyme catalytic subunit 1, APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, mRNA(cytosine(6666)) deaminase 1.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M236_CONTE
Sequence: MMSKLGVLLTICLLLFPHTAVPLDGDQHADQPAERLQDDISSEHHPMLNSIRRREQNQFMSFTSVKLRDSRGERCCGPTACMAGCRPCCG
What are the official names of this protein?
Conotoxin TxMMSK-06.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YF010_YEAST
Sequence: MYTFSYSTHNELLEFFHLFVTIQWLALIGQKTLSQFCLYRNAAVVGFFIRFTFGTPIFLQLL
What are the official names of this protein?
Uncharacterized protein YFR010W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DPCKG_METS5
Sequence: MEVRYKRKVDLCFRPPRTVRAELSRPYGILFSNNAKLLSYLGQFERIITVGDVVTSLVTRSGIRPFLSVVDGKTRRNVSISGERSSEVITNEAGILRFSAMSKIKEIMYGREPRSLFVNGEDDMMVIPIILYGKNGDLVVYGQPNAGAVCLENWEGSRWRVMDIFSKFTAELC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: PRRC1_MOUSE
Sequence: MMEESGIETTPPGTPPLHPAGLAAVPSTEAHSAATSSFSSPNVSGMESLPPHVYSTPQPSLPPVQPSAPPPFVSMSPAPSVPLSGTSVPPSVSPSPATAFSGPPMSHFPPATSASGALLSAPPSGPPISGFSVGTTYDITRGHAGRAPQTPLMPSFSAPPVTGILPAPITQQASMTSLAQGPGTTSAITFPEEQEDPRINRGQDDAPAGGIWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRSGAIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIRLEAFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVSRTDWHLAFTGMSRRQMIYSAAKAVAGMYKQRLPPRPM
What are the official names of this protein?
Protein PRRC1, Proline-rich and coiled-coil-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: THIM_HELPH
Sequence: MVLKELRQKRPLVHNITNYVAAQFVANGLLALGASPLMSDAIDEMQDLAKISDALAINIGTINERAILCAKEAIKHYKALNKPIVLDPVGCSASALRHDTSLELLKSGGISALRGNAAELGSLVGISCESKGLDSQDANTPVEIIKRVAQKYFVIAVMTGKTDYVSDGKKVLSITGGSEYLALITGAGCLHTAACASFLGLKKDPLDSMAQLCALYKQASFNAQKKALENNGSNGSFLFYFLDALSLPIKLENSLIKEVL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PSB_SACVD
Sequence: MEHTPRNAGFALPAAYMSTMTSSFIDFLKAEAPDLLPRARVENMPAVPGGGSAFEPPHGTTIVASTFNGGVLIAGDRRATTGNTIASRDLEKVYVTDAYSAVGIAGTAGIALELVRLYTVELAHYEKIEGVSLSLDGKANKLANMVKGNLDGALAGLAVLPLFVGYDIDADDPKRAGRIVSFDVTGGRYEENAGYHAIGSGAVYAKSSLKKLYDPEADADTAVRTAIEALYDAADDDTATGGPDLVRRIYPTVVTITAEHGAVMLPQEETASIAESVVRERSERPGQLG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_SYNE7
Sequence: MFLAADRPTTDLPADLPAAIAALKQELNAVILAHYYQEAAIQDVADYIGDSLGLSRQAAAADADVIVFAGVHFMAETAKILNPQRQVLLPDLAAGCSLADSCPPEAFAAFKAAHPNHIVISYINCTAEIKALSDIICTSSNAVKIVQQIPVDQPIIFAPDRNLGRYVMQQTGRDLVLWDGSCIVHETFSEQRLLELQARHPDAEIIAHPECETPVLDQARFIGSTTALLNYSLNSPSREFIVVTEPGIIHQMQQAAPEKTFIPAPPQDTTCACNECPFMRLNTLEKLYLCMRDRRPEIQIPEETRLAALRPIERMLAMSA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBTR_KLEAE
Sequence: MKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINRQASMLRSKKSHVIGMIIPKYDNRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVKAMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGSLSPSVISDNYGGAKALTHKILANSARRRGELAPLTFIGGRRATITPASVYAASTMRIASWGLACRRRIFWLPAIRKATLRTACRSGLAARRRCCRGYLLTRRYPWKGLCAGCRRWV
What is the function of this protein?
Repressor for the genes of the ribitol operon.  Binds D-ribulose as an inducer.
What are the official names of this protein?
Ribitol operon repressor, Rbt operon repressor.
Protein: RBSA_TRIV2
Sequence: MTTNIKTDFSPPATATPVLEMQGIAKRFHGVPALQGVNLTIYPGEVHALMGENGAGKSTLMKILAGAYIADEGEIRINGKGVKITDPGTARQAGINLIYQELNVAPNLTVTENIFMGSELTRGQFLDRKAMELEAQQVLASLGASFAPTDIVGTLAIAEQQQVEIARALKDNSRILVMDEPTAALSDRETERLFEVIRKLRNDGIAIIYISHRMEEIYALADRISVLRDGQYIGSLTREEISPQRLVQMMVGRSMQDFYEHQRQSNPGPVVLEVRNISDGRKVQPASFQLRAGEILGLAGLVGAGRTEVSRLIFGADRKVSGEVFLNGKKLEIHSPSDAIAVGIGYVPEDRKDQGLFLEMSSRKNIGLNRLKQDANLGIVNWGSVNKIATDAVENFHIRLANLEIRAVDLSGGNQQKLLLARWLAINPRVLMLDEPTRGVDIGAKSEIYRIISDLSAQGVAILMVSSELPEIVGLSDRVLVMREGQLVGELDNSIGKEITQENIMHYATGASEVTAS
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: APOE_PONPY
Sequence: MKVLWAALLVTFLAGCQAKVEQVVETEPEPELRQQAEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELTALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRARLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRVRAATVGSVAGKPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: MIC27_HUMAN
Sequence: MAAIRMGKLTTMPAGLIYASVSVHAAKQEESKKQLVKPEQLPIYTAPPLQSKYVEEQPGHLQMGFASIRTATGCYIGWCKGVYVFVKNGIMDTVQFGKDAYVYLKNPPRDFLPKMGVITVSGLAGLVSARKGSKFKKITYPLGLATLGATVCYPVQSVIIAKVTAKKVYATSQQIFGAVKSLWTKSSKEESLPKPKEKTKLGSSSEIEVPAKTTHVLKHSVPLPTELSSEAKTKSESTSGATQFMPDPKLMDHGQSHPEDIDMYSTRS
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol.  Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).
What are the official names of this protein?
MICOS complex subunit MIC27, Apolipoprotein O-like, Protein FAM121A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion.
Protein: IF2G_PONAB
Sequence: MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGPLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD
What is the function of this protein?
As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis.  In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation.  The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing.  This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP.  Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B (By similarity).  Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: HEMA_I84A3
Sequence: MYKVVVIIALLGAVKGLDRICLGHHAVANGTIVKTLTNEQEEVTNATETVESTNLNKLCMKGRSYKDLGNCHPVGMLIGTPVCDPHLTGTWDTLIERENAIAHCYPGATINEEALRQKIMESGGISKMSTGFTYGSSITSAGTTKACMRNGGDSFYAELKWLVSKTKGQNFPQTTNTYRNTDTAEHLIIWGIHHPSSTQEKNDLYGTQSLSISVESSTYQNNFVPVVGARPQVNGQSGRIDFHWTLVQPGDNITFSDNGGLIAPSRVSKLTGRDLGIQSEALIDNSCESKCFWRGGSINTKLPFQNLSPRTVGQCPKYVNQRSLLLATGMRNVPEVVQGRGLFGAIAGFIENGWEGMVDGWYGFRHQNAQGTGQAADYKSTQAAIDQITGKLNRLIEKTNTEFESIESEFSETEHQIGNVINWTKDSITDIWTYNAELLVAMENQHTIDMADSEMLNLYERVRKQLRQNAEEDGKGCFEIYHTCDDSCMESIRNNTYDHSQYREEALLNRLNINPVKLSSGYKDIILWFSFGESCFVLLAVVMGLVFFCLKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: TRPA_GLOVI
Sequence: MSSLASPGRIARVFAALHARREVAFIPFITAGDPDLETTAEALLTLDRNGADLLELGLPYSDPLADGPTIQAAATRALARGTTPGAVLDLVARLTPELRAPLIVFTYFNLILAVGIEAFVERLAASGASGLLVPDLPVEEGDALQTAANVQGLDVIWLVAPTSPPERLRRIAERTTGFVYLVSTTGVTGARTQVASSVRTSLAQLRALTTRPVAVGFGISTPEQAHEVASLGADGVIVGSACVQLLATAAPEERLGQLAEFCRQLKKASQTLPVKS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: GAR1_CANGA
Sequence: MSFRGGFRGGRGGSRGGFGGRGGARGGRPIQQGPPDTVLEMGEFMHPCEGDVVCRSINTKVPYFNAPIYLENKTQVGKVDEILGPLNEVYFTIKCGEGVQATSFKEGDKFYIAPDKLLPIERFIPKPKVAGPPKPKNKKKRSGAPAGRGGARGGFGGRGGSRGGFGGRGGSRGGFGGRGGSRGGFGGRGGSRGGFGGRGGSRGGFGGRGGSRGGFGGRGGRS
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y05J_BPT4
Sequence: MKVLFVIYVMIQYNYPMFTYNLVNNIINMIQRSM
What are the official names of this protein?
Uncharacterized 4.2 kDa protein in mobD-ri intergenic region.
Protein: NSP1_ROTHD
Sequence: MATFKDACYQYKKLNKLNNAVLKLGANDVWRPSTLTKRKGWCLDCCQHTDLTYCQGCLIYHVCEWCSQYNRCFLDDDPHLLRMRTFRNEITKSDLENLINMYNTLFPINKKIVHKFANTIKQHKCRNEYSTQWYNHFLMPITLQSLSIELDGDIYYIFGYYDDMHKINQTPFSFTNLISKYDMLLLDSINFDRMAFLPLTLQQEYALRYFSKSRFITERRKCIEILHFSDNILDNLHNPNFTLQVIRNCSNMSVEWNKACNIIRNISDYFDILKSSHTEFYNISPRCRMFTQYKLKIASKLIKPNYVASNHNSLATEVHNCKWCSINNNSIVWNDFRIKNVYNDIFNFIRALVKSNLYVGHCSSEEKIYESIKEVLNVCKENEWNMLVTEMFNQLEPIKLNENNYILLNYEINWNVMNVLINSIGKIPKILTLSDVILILRIIIYDWFDIRFMRNTPMTTFTVNKLKQLYEKDRTAEHDSRISDIE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: MMPL8_MYCBP
Sequence: MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVRRPWVVIAFWVALAGLLAPTVPSLDAISQRHPVAILPSDAPVLVSTRQMTAAFREAGLQSVAVVVLSDAKGLGAADERSYKELVDALRRDTRDVVMLQDFVTTPPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARVADIVEHQVAGSTLTANLTGPAATVADLNLTGQRDRSRIEFAITILLLVILLIIYRNPITMVLPLITIGMSVVVAQRLVAIAGLAGLGIANQSIIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQAVKKALTSIGKVIAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALMVLTGRRGWIAPRRDLTRRFWRSSGVHIVRRPKTHLLASALVLVILAGCAGLARYNYDDRKTLPASVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRTPKALADLEQMVQRVSQVPGVAMVRGITRPAGRSLEQARTSWQAGEVGSKLDEGSKQIAAHTGDIDKLAGGANLMASKLGDVRAQVNRAISTVGGLIDALAYLQDLLGGNRVLGELEGAEKLIGSMRALGDTIDADASFVANNTEWASPVLGALDSSPMCTADPACASARTELQRLVTARDDGTLAKISELARQLQATRAVQTLAATVSGLRGALATVIRAMGSLGMSSPGGVRSKINLVNKGVNDLADGSRQLAEGVQLLVDQVKKMGFGLGEASAFLLAMKDTATTPAMAGFYIPPELLSYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISPDGHSIRYLIQTDLNPFSTAAMDQIDAITAAARGAQPNTALADAKVSVVGLPVVLKDTRDYSDHDLRLIIAMTVCIVLLILIVLLRAIVAPLYLIGSVIVSYLAALGIGVIVFQFLLGQEMHWSIPGLTFVILVAVGADYNMLLISRLREEAVLGVRSGVIRTVASTGGVITAAGLIMAASMYGLVFASLGSVVQGAFVLGTGLLLDTFLVRTVTVPAIAVLVGQANWWLPSSWRPATWWPLGRRRGRAQRTKRKPLLPKEEEEQSPPDDDDLIGLWLHDGLRL
What are the official names of this protein?
Probable transport protein MmpL8.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_DESOH
Sequence: MGTISASLVKELREKTGAGMMDCKEALTACDGDIEKAVDFLRQKGLAKAAKRSGRETSEGIVESYIHMGGKIGVMVEVNCESDFVAKTDDFKEFARNVAMQIAATNPAGIAPEDVPADLLERERQVYRAQVLEMGKPENMVDKIVDGKIKKFFKESCLIEQQYVKNPDITIGDYLNETVAKIGESIRIKRFARFALGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLBLE_DICDI
Sequence: MKLFILLIVIVFLISNSYSLSSSDSSSDSGSDVQYYSLTSQFQVVQGKQIPGSIAWGYFKDEMNKDGWGKLSIETVSTVSDNIAFKAAGYLEGYLTWEYIYKFSGNYFNSFFNTSNIKEIPTETLTFVSDNWEYMMERVNSSSTTDPYWIQIRNAMSQQIGLYEGYNAAAGEDYQKTFIEIYMINLYGDMGDIVTLTTTPNNEFIPMDRKEVEQLMATTGHCTSIIKLTNNCSDLMSAHTSWADFSVMIRIYKRINIPVASTPYGSETLFSSYPGLLVSIDDFYQIRPSKLHLTETLNTILNQTLYQQINAQSFMYWVRNLVANRLANNGFQWVSIFVENNSGTNNIQFVVLDYKLFTPYSTELQSDLLWIVEQYPGGYQAADVTLTLWEQGYWPSYNRPYFEEVFDILGYPYYVEKFGDLFTYEYNPRANIFRRDHSKLETLQDMMNIIDYNQYKTDPFSMGYPGNSINARFDIKGGSLPSGNPIYSWFYHGTHGGIDGKAINYDMVNSFTAVARNGPTVTSDCPPFNWNDWSLISHQYMPQIYNFTWISINI
What is the function of this protein?
Probable phospholipase.
What are the official names of this protein?
Phospholipase B-like protein E.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Secreted.