PharMolix/UniProtQA huggingface dataset:
Protein: FTMD_NEOFI
Sequence: MFNLPEVATRLSQNVELLVDEIDKTGSQPNCGNPTLLGPKGLAARDEIILAAEKLLQQGRGPGPSLLSLLESAVDIGTIQTLIRLEVPDQVPPTGSIPYDALVKKLKTPVAPELLQRLIRFTRLAGFLDEDEEGAVKHSPMSAIFVSDPDSAGQARFMADFGIRPCSFIYESIKLDPSGEATRQGPLALMAREPGAREGPTFFEVLEKDPVNRNRWHDGMAVHNDSMVRHVADAYDWDTVKSLVDIGGSEGHVAAVIANAFAHIQITVQDRPEIIEKARQRVDRHRNITFEEHDFFTPQPRIADAYFLRLILHDWNDADCTRIVRQISSALRPGARLLIMDAVLPEPGEGSLQSERQLRRSDIGMYTLFSAKERSLVQMRRLVEDCDDRLRFEKLYTPPGSHASMLSWICE
What is the function of this protein?
6-hydroxytryprostatin B O-methyltransferase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities (PubMed:23109474).  The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmPS/ftmA (By similarity).  Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B (By similarity).  The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively (By similarity).  The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (By similarity).  FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B (By similarity).  Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties (By similarity).  Finally, verruculogen is further converted to fumitremorgin A by the verruculogen prenyltransferase ftmPT3 (PubMed:23109474).
What are the official names of this protein?
6-hydroxytryprostatin B O-methyltransferase, Fumitremorgin biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: RL4_LIMRJ
Sequence: MTSVNLYKQDGSQNGTVELNDAVFGVEPNENVVFDAILRQRASLRQGTHAVKNRSAVSGGGKKPWRQKGTGRARQGSIRSPQFRGGGIVFGPTPRSYKYSLPRKVRQLAIKSALSQKVLDNSFVVVDALNFDAPKTKEFADVMGNLNVAEKTLVVVTDDDKNAALSARNLANATVVTPAGVNILNVVDNQKIVITKSALSQVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: OMPT_ECOLI
Sequence: MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGAGIENYNFITTAGLKYTF
What is the function of this protein?
Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins.  This protease has a specificity for paired basic residues.
What are the official names of this protein?
Protease 7, Omptin, Outer membrane protein 3B, Protease A, Protease VII.
What is the protein family that this protein belongs to?
Belongs to the peptidase A26 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CH60_BLOFL
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPVITKDGVSVAREIELEDKFENMGAQMVKEVASKANDSAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKKLSVPCSDPKAIAQVGTISANSDETVGKLIAQAMDKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFVNKPESGTVELEHPFILLADKKISNIREMLPILESVAKSGKPLLIIAEDVEGEALATLVVNNMRGIVKVTAVKAPGFGDRRKAMLQDIAILTSGTVISEEIGLELEKATLEDMGQAKRVLITKDATTIIDGVGNKSSIDSRVAQINQQRDEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVANAIRNLCGDNEDQNVGIKVARRAMEAPLRQIMANAGEEPSVIANNVRSGEGNTGYNAATEKYGNMIELGILDPTKVTRSALQYAASIAGLMITTECMVTELPKEDKPDLGGGNPGGAGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPRT_HUMAN
Sequence: MASLAALALSLLLRLQLPPLPGARAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDTDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRRNAYSYSYYLKLAKKQKETQSGAQREMGPVASADKPTTKLSASRNDEGFSSSSQDVNGFTDGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF
What is the function of this protein?
May be involved in both signal transduction and cellular adhesion in the CNS.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase T, R-PTP-T, Receptor-type tyrosine-protein phosphatase rho, RPTP-rho.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PSBE_PIPCE
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DCD_RICAH
Sequence: MAIMSDKWIKEAVINQSMISPFAEKQVRVHNKEKIISYGLSSYGYDARVSNEFKIFTNINSTTVDPKNFSEYNLVDREVDVCIIPPNSFALGRTIEYFKIPRDVLVICVGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGACQFLFLKSDQICDTSYADRQGKYMKQVGVTLPLT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: WZYE_SALTY
Sequence: MSLMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVPRKPLFTMNRVETHLTWVILMGIALVSVAIFFMHNGFLLFRLHSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYHNIEFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQVEGKL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FG2KO_SOYBN
Sequence: MPSELAMNNDELHVVMFPFLAFGHISPFVQLSNKLFSHGVHVTFLSAASNIPRIRSTLNLNPAINVISLKFPNGITNTAELPPHLAGNLIHALDLTQDQVKSLLLELKPHYVFFDFAQHWLPKLASEVGIKSVHFSVYSAISDAYITVPSRFADVEGRNITFEDLKKPPPGYPQNSNISLKAFEAMDFMFLFTRFGEKNLTGYERVLQSLGECSFIVFKTCKEIEGPYLDYIETQFRKPVLLSGPLVPEPSTDVLEEKWSKWLDGFPAKSVILCSFGSETFLSDYQIKELASGLELTGLPFILVLNFPSNLSAKAELERALPKGYLERVKNRGVVHSGWFQQQLVLKHSSVGCYVCHGGFSSVIEAMVNECQLVLLPFKGDQFFNSKLIANDLKAGVEVNRSDEDGFFHKEDILEALKTVMLEDNKEQGKQIRENHMQWSKFLSNKEIQNKFITDLVAQLKSMA
What is the function of this protein?
Flavonol 3-O-glucoside (1->6) rhamnosyltransferase converting kaempferol 3-O-glucoside to kaempferol 3-O-rutinoside and utilizing 3-O-glucosylated/galactosylated flavonols and UDP-rhamnose as substrates.  Prefers kaempferol to quercetin as an aglycon, and 3-O-galactosides to 3-O-glucosides as a glycosylation pattern.
What are the official names of this protein?
UDP-glycosyltransferase 79A6, Flavonol 3-O-glucoside (1->6) rhamnosyltransferase, GmF3G6''Rt-a.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: END4_CARHZ
Sequence: MNVGLHLSIAGGLLKLKERIIKNKTEGVQIFSRSPRGGEAKPFNEKELKGFLEFKEEYKLYPLVVHVPYVMNLASPEEEMFQKSVAMIREDLYRSDQLHADFLVVHVGSHRGAGEERGLARMVEGLKILLSENFKTRILIENTAGSGNEMGYSLDHLAYIISETGHEELGICLDTCHLLAAGYDDVSPEGISAFSREFREKIGEERFCLLHVNDSKHPIGSRKDRHENLEQGYIGREGFINLLNSPFFKRVPWILETPEPGIEEDLVKLKKLREEVLKIPADR
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL4_WOLPP
Sequence: MECELVDLSNNNVGSVELNPLIFSAKQKLSILHDIVRWQLAKRRVGAHKTKGISDVSGTTAKPYGQKRTGRARQGSLRSPQFRGGGIIFGPVVRSHAYSLNKKVRKFGLKIALSLKYLNNQVVVLDSLNVDVKKTSKMCEYIKNFKFSSFLIVGDYGDDLLRAAKNLHYVDLIKPIGLNVFDILNHECVMLTKDTLKHLEGRLL
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: IL12A_CEREL
Sequence: MCPLRSLLLLSTLVLLHHLPHLSLGRSLPPTTAGPGRSCLNYSQNLLRAVSDTLQKARQTLEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLVSRETSLITHGSCLASGKTSFMTTLCLKSIYEDLKMYHMEFQAMNAKLLMDPKRQIFLDQNMLAAIAELMQALNFNSETVPQKPSLEEMDFYKTKVKLCILLHAFRIRAVTIDRMMSYLSSS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SAR1B_RAT
Sequence: MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHLQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID
What is the function of this protein?
GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus.  Activated by the guanine nucleotide exchange factor PREB.  Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity).  Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (By similarity).
What are the official names of this protein?
GTP-binding protein SAR1b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
Protein: Y5371_ARATH
Sequence: MAHSGNGESFHDPLRGFIQRNCFRWNNQKLILQCFMALAFVGITSSTTQPDIEGGALLQLRDSLNDSSNRLKWTRDFVSPCYSWSYVTCRGQSVVALNLASSGFTGTLSPAITKLKFLVTLELQNNSLSGALPDSLGNMVNLQTLNLSVNSFSGSIPASWSQLSNLKHLDLSSNNLTGSIPTQFFSIPTFDFSGTQLICGKSLNQPCSSSSRLPVTSSKKKLRDITLTASCVASIILFLGAMVMYHHHRVRRTKYDIFFDVAGEDDRKISFGQLKRFSLREIQLATDSFNESNLIGQGGFGKVYRGLLPDKTKVAVKRLADYFSPGGEAAFQREIQLISVAVHKNLLRLIGFCTTSSERILVYPYMENLSVAYRLRDLKAGEEGLDWPTRKRVAFGSAHGLEYLHEHCNPKIIHRDLKAANILLDNNFEPVLGDFGLAKLVDTSLTHVTTQVRGTMGHIAPEYLCTGKSSEKTDVFGYGITLLELVTGQRAIDFSRLEEEENILLLDHIKKLLREQRLRDIVDSNLTTYDSKEVETIVQVALLCTQGSPEDRPAMSEVVKMLQGTGGLAEKWTEWEQLEEVRNKEALLLPTLPATWDEEETTVDQESIRLSTAR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At5g63710.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HEM1_SOLUE
Sequence: MKLLITGVSHKTAPVEVRECLAFREETLPAALADLKACEGVSEAVILSTCNRVEISLTTEDAVDPREIVDNFLSRHKAVSSASIGPHLYRHEGRDAIHHLFRVAASLDSMVVGEPQILGQLKVAYAAAKDCGALCGWLDGLMSRSFSVAKRVRSETGIGQMAVSVSYAAVELARKIFGSLTNRTVMIVGAGKMSELAARHLRRSGASHVFVTNRTHERAVDMAKLFQGTPVEYARFTAMLPEVDILIASSGAPHYILHKDEMQRVISARRNKPMFLIDIAVPRNIEPAINDLDNVFLYDIDDLQEVVNSNLRERMKEADHAELLVTEEVDRMMARMKVAEVTPVIVSLQEQLEQIRSGEMEKVRRRFGPFTAQQEEALEALTRGIINKVAHGPISELRSQAGKPDGAPAIAAIRKAFHLQD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CD37L_PONAB
Sequence: MEQPWPPPGPWSLPRAEGEAEEENDLDVFPSSPRCPQLPGGSAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQIAVSELRQREEEWRQKEEALVQREKMCLWSMDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSINTALCSLNSVVHKEDDEPKMMDTV
What is the function of this protein?
Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.
What are the official names of this protein?
Hsp90 co-chaperone Cdc37-like 1.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRLA_ECOLI
Sequence: MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
What is the function of this protein?
Is likely involved in the transport of fructoselysine and psicoselysine to the cytoplasm, where they are degraded.
What are the official names of this protein?
Probable fructoselysine/psicoselysine transporter FrlA.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD2_CAUVC
Sequence: MSDPVLALRGLERVYKTEAGDLPVLRGVDLDVYPGEVVGLIGPSGSGKSSLLHSAGLLERPDAGLVALEGRDCSKLSERARTRIRLGTVGFVYQFHHLLPEFSALENVAMPLTIAGKSRREAEARARELLESLGLGHRLNHQPAQMSGGEQQRVAIARALANRPKLLLADEPTGNLDPATSTAVFQALYQVCREQGVAAVIATHNMELARYMDRVVALKDGHLELQRV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RDRP_DXV96
Sequence: MSDIFNQQGLKSKFSNIVKNEGQGDSDIREVFNELARPQAEVGRDIEYSELSQALNDNSVKVFRPQPYDELVNIPFIEAASPRMMALYGELLDSKDVSLPVGSGLHIPTYKPGHEVTPPLLTLPNSLSYEYMHYIANSANDTWDKQIYETLKELLVAQATNRFSTGSLLGQVKRVAAGQDVAYGRKGHHKNKSFKEMGITPYRVMEWLDEYMPISDDEPEITLSNTLDWLVYTPEEAELMGVPDSLPDITQSSAAGLPWLGKKKGEVAVSALITANMLIKDVSQLLKENLFTGSNNPLDPKKEGVAEVTTKNPRRAADQFSRQVLDRIIKEYSYTMMGLLFPKGERYAIADHLTKTRNIWSASYVTHLIGSTISDQPAKRMLNVLTSTSRTPSLAKFSPTQGGMEALINIILNATDIVELVYADNAYIYYPNEDIWYSIDLTKGEANCTRDVAMTTAMYLLTRGWTSKQGTPIYNYTWAYLALYGIPYMTVDSISVLKNFQIKNPGQGSGNPWTFLNNHVLTTILMNKWSEIGKPQPSPDVIEKLASMTGIDFKVELVVTNFREKLIAASRHSIPTSNRVEPRTIVEMDMLGWDVTHTEFGFTPVLSKERLFKSIACPQPPSSTFQTSVAKQVHKYIQNVALLYVGAWAYPCIAQTIEGYALNHWNTINIMIRNKEYDLDKAIGKAVEASPFSEVISLLSLDRPMHEQNYAQVLYQQKTIEKKEAKPKVSNPLYKRDKETYHEYTTRMARMRINDDMVGPQWEPIINLVTKLYPREATGENQKSRESMTRVKIRGLLENMERQLESNGRSMDVWYNAYLTGKKPSGVDKKLATLLVLLAPKRTKKLPSGVYQKLLGYPPIDKSPVPSLTSDEAYLYDTNSLEYNRIAYVSKLNEDDITVYANKYMVYSSTLLSNLLPDKVDWPELRSMNVEGASDPYQVKGYKKKELKPRFGEEILDDEPTGKKSSSEKRRLQRKGQKAKLQRQAATGTTFVRKPLN
What is the function of this protein?
RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA.  May also contain guanylyl and methyl transferase activities (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, RDRP, Protein VP1.
What are the subcellular locations of this protein?
Virion. Note=Minor amounts are incorporated in the virion.
Protein: PYP_HALSE
Sequence: MNIVHFGSDDIENSLANMSDQDLNQLAFGAIQLDASGKVLQYNAAEEGITGRDPKSVIGKNFFEDVAPCTKSQEFQGRFKEGVANGNLATMFEYVFDYQMKPTKVKVHMKKALVDDSYWIFVKRL
What is the function of this protein?
Photoactive blue light protein.  Probably functions as a photoreceptor for a negative phototaxis response (By similarity).
What are the official names of this protein?
Photoactive yellow protein, PYP.
What is the protein family that this protein belongs to?
Belongs to the photoactive yellow protein family.
Protein: PHF14_MOUSE
Sequence: MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIQVKEEQLKNSTEEIMPSDKQLIKMEKKEEEENGERPRKKKEKEKEKEKEREKDKEKATVSDSAAASAAGTTPATSPPAVTSPSVPTTTTTTTEEQVSEPKKWNLRRNRPLLDFVSMEELNAMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDDDEGSGSEEDENDEGNDEDHSSPASEAGGKKKRSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNVPAILRAPKERKPSKKEGGTQKTSALPTVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEAEMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECSTCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAEKKNASQELSMEQKTPKK
What is the function of this protein?
Histone-binding protein (By similarity).  Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3) (By similarity).  Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation (PubMed:22730381).  Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells (PubMed:33035772).
What are the official names of this protein?
PHD finger protein 14.
Protein: FADJ_SALA4
Sequence: MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.