PharMolix/UniProtQA huggingface dataset:
Protein: WWC2_HUMAN
Sequence: MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGVYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYKEQGFETLQQIDKKMSGGQSGYELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNIGRSEPDLRCSPVNSHLCLSRQTLDAGSQTSISGDIGVRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQFVTPQKRTQDELERLEAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLTTYLHSQLKSLSASTLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSTELYYSSQSDQIDVDYQYKLDFLLQEKSGYIPSGPITTIHENEVVKSPSQPGQSGLCGVAAAATGHTPPLAEAPKSVASLSSRSSLSSLSPPGSPLVLEGTFPMSSSHDASLHQFTADFEDCELSSHFADISLIENQILLDSDSGGASQSLSEDKDLNECAREPLYEGTADVEKSLPKRRVIHLLGEKTTCVSAAVSDESVAGDSGVYEAFVKQPSEMEDVTYSEEDVAIVETAQVQIGLRYNAKSSSFMVIIAQLRNLHAFLIPHTSKVYFRVAVLPSSTDVSCLFRTKVHPPTESILFNDVFRVAISQTALQQKTLRVDLCSVSKHRREECLAGTQISLADLPFSSEVFTLWYNLLPSKQMPCKKNEENEDSVFQPNQPLVDSIDLDAVSALLARTSAELLAVEQELAQEEEEESGQEEPRGPDGDWLTMLREASDEIVAEKEAEVKLPEDSSCTEDLSSCTSVPEMNEDGNRKESNCAKDLRSQPPTRIPTLVDKETNTDEAANDNMAVRPKERSSLSSRQHPFVRSSVIVRSQTFSPGERNQYICRLNRSDSDSSTLAKKSLFVRNSTERRSLRVKRTVCQSVLRRTTQECPVRTSLDLELDLQASLTRQSRLNDELQALRDLRQKLEELKAQGETDLPPGVLEDERFQRLLKQAEKQAEQSKEEQKQGLNAEKLMRQVSKDVCRLREQSQKVPRQVQSFREKIAYFTRAKISIPSLPADDV
What are the official names of this protein?
Protein WWC2, BH-3-only member B, WW domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the WWC family.
Protein: DIAA_SALPC
Sequence: MLERIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHHSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: TATA_HELHP
Sequence: MHPPSITQLLIILLIIVLLFGAKKIPELAKGLGSGIKNFKKAVKEDEEDNQSEENTKSQIKQSESKNENVSKTHTDSQKQDT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PYRC_TRIL1
Sequence: MNLLIKGGRVIDPSQGIDDTLDVVVENGLVKEIGKGLATSAGAETIDASGKYVVPGLIDMHVHLRDPGLEYKEDIISGTRAAVAGGFTSVCCMPNTKPAIDNKAIASYIINKAKTEGACNVFPVGTITQGMHGDRLAEMGELKESGCVAVSDDGKPVKNSELMRRALQYAAGIGIMVISHAEELELVGEGVMNEGFTSTELGLKGIPRVAEDIATAREIMLAEYVGAPIHIAHVSTKGAVRIIREAKGRGVKVTCETAPHYFTLTDDAVRGYNTNAKMNPPLREADDLAAIKAGLKDGTIDCIATDHAPHHLDEKDVEFNEAMNGIVGLETSLPLSLKLVDEGVLNLSQLIEKMSCKPSELLGLGRGSLKAGNVADITVIDPAKQWTVTESALASKSKNSPWLGATMAGAAACTVVGGKIVFSGR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: YKK5_CAEEL
Sequence: MSYMEQIPPYEYYKYVFGTRCAVLACSSFELMMVLLGSLGDSNVLAKLFYLVFLGASAAVSGFNLQQNIDGRDEIKKITGSGDNETRGKAAALVGIPALAAVFVFLCVSGHAFFSLFVLVHVLASIGQLGIEAYEVRNGFCIKAPENKKAVADSYDQNYQILNMVQDSVFDKK
What are the official names of this protein?
Uncharacterized protein C02F5.5.
Protein: CLD11_MOUSE
Sequence: MVATCLQVVGFVTSFVGWIGIIVTTSTNDWVVTCSYTIPTCRKMDELGSKGLWADCVMATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGHEPGVAKYRRAQLAGVLLILLALCAIVATIWFPVCAHREITIVSFGYSLYAGWIGAVMCLVGGCVIVCCSGDAQSFGENRFYYSSGSSSPTHAKSAHV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-11, Oligodendrocyte transmembrane protein, Oligodendrocyte-specific protein.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: RR11_LACSA
Sequence: MAKAIPKKGSRGRIGSRKSTRKIPKGVIHIQASFNNTIVTVTDVRGRVVSWSSAGTSGFRGTKRGTPFAAQTAAGHAIRAVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLTFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS11_ECOLI
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity).
What are the official names of this protein?
30S ribosomal protein S11, Small ribosomal subunit protein uS11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: COAA_STRP4
Sequence: MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTVTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_MESH7
Sequence: MLFSLRRLKKLANLEAFSDQKVIDSLINLGFEVDQITKLNEISGIKFGQILEIRKNPEADNLWICKVQFADKIREIQTTAKNVIENKQVLAFIPGSKSGNTTFLAKKLRGHISEGMLISAAELGFNKHLLNSELDQGVLVFDPIFDLESNPLKVLELDDLILDIKLLWNRPDGNSYLVLANELAAFFKTDFSLINKEITGKFYSELKIINKTDSKIFALEIQKLPKLALVDIFLLLKSEVKIDNLAQNFANFILIYTGQPCYCLQLEKNQQKVELIEQKVKIKYEPDAISSYHFLDQEKKPLLIPEFSDQIIMENNSFFLIMPKFNLLKVKQIKQFLKKNSLKLTQLGKNYNYGTTFIALSFLNFFLEDQKIDFSWPINFDKSLISKKTFLDLNYNELKEILGLELSQEDISKTNLILEKIGYNFDNTSFSPPFYRVDIEFFADYAADFLRFYGLEKLKDCKLEQVKAKIPNPDFEPVKLKTLGYYETNSFLLISKKEDFNPLELKSQDLLTFPSQEHTKIRYSLAWQLAKITKYNQKRKITEINLYEKGSIAGWNHSLALASTIYTSEDLKKHLKILYNYDFDFLPADSEFLNPEKSQFIYLDNVLVGWLGQVVEKYNYENVTFLEILLSKVEKIPKKEGGKIKFRPYDNSQLKYRDITLSLPMKDIPDPYLKVIQKIPEIFSVKLINYVIINNQQKITYRITGPDQVCAEIDKFYK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_SORBI
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: G6PI_RHIME
Sequence: MKALVENLKATARETDATDIRAAFAADPNRFSRFSTAFDDLLFDYSKCAVNDRIIDGLEALAKAAKVEEKRDAMFRGDIINITEERAVLHTALRNRSNRPVLVDGKDVMPDVNAVLEAMGKFADDIRSGALKGATGKKITDVVNIGIGGSDLGPVMATLALAPFHDGPRLHFVSNVDGAHIADTLTLLDPETSLFIVASKTFTTIETMTNAATARAFIAGKLGEAAVGHHFAAVSTALDKVGAFGIDAARVFGFWDWVGGRYSIWSAIGLPLMIAIGKENFGRFLDGGHAIDEHFRSAPLRQNIPMLLGLIGFYNRNVLGYPSRAILPYDQRLTRFPAYLQQLDMESNGKGVTLDSQPVEFSTGPVVWGEPGTNGQHAFYQLIHQGTDVIPAEFMIAANGHEKDLRHQHQLLMANCLAQSEALMKGRTLAEAKAQLTSKGMDDAKADKIAPHRVFTGNRPSLTIVYDQLDPFALGRLIALYEHRVFVEGALFNINSFDQWGVELGKELATGLLPVIEGKESAEGHDSSTAGLVAALLKAAR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_KINRD
Sequence: MARVKRAVNAQKKRRTVLEQASGYRGQRSRLYRKAKEQVTHSLVYAYRDRKARKGDFRRLWIQRINAAARAEGMTYNRFIQGLKAAEIEVDRRMLAELAVSDPAAFGALVRTAKAALPVAPVAAEGTAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: YOQ7_CAEEL
Sequence: MQFFISSAILFSYAFCQSIPNVILTGEPRVVARRILNVDMKAAQQLALPDDQQHVRYQVNVVRNQENPSDSTYLTGERTPVTVYRRILRPARITFTGDGVITDSWQGTSDAVEMESWTLNRRPTIDGSFVQPTQNQQGAFH
What are the official names of this protein?
Uncharacterized protein ZK512.7.
Protein: TBAD_PHYPO
Sequence: MREVISIHIGQAGTQVGNACWELYCLEHGIQPDGQMPSDKSVGYGDDAFNTFFSETGAGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLCLDRVRKLADQCTGLQGFLVFHSVGGGTGSGFGSLLLERLSVDYGKKSKLDFCVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAFMLDNEAIYDICKRALDIDRPTYTNLNRLVAQVISSLTTSLRFDGALNVDITEFQTNLVPYPRIHFMLCSYAPVISAEKAYHEQLTVAEITNSVFEPANMMAKCDPRHGKYMACCLMYRGDVVPKDVNASVAVIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAESSEAGGDEEGEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1A chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Mitosis in the slime mold Plasmodium differs from the process in many eukaryotes. The tubulin chains must be transported to the nuclei for intranuclear assembly of the spindle.
Protein: THF1_PROMP
Sequence: MKEKLTVSDSKKLFHEQFPYVIPGLYKRIVDEMLVELNLLNHQNEFIQDDLFCVGLTETFKELTKGYKPEEHLRVLFESLCNSSNFEPKKIKEASKKTLEVYKDKSLKEISILLKQKSDSNLYSSRILNLGIYLIIANATDFKDIKDPEKNKIISDIINKLNLSFNKAEKDIGIYKSSILKMEQAKELLQEAKIKDKKEKKK
What is the function of this protein?
May be involved in photosynthetic membrane biogenesis.
What are the official names of this protein?
Protein Thf1.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
Protein: UBIA_ECOLC
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVD_CERS1
Sequence: MPAFRSRTSTHGRNMAGARGLWRATGVKDSDFGKPIIAIVNSFTQFVPGHVHLKDLGQLVAREVEAAGGIAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKVTLGDGRTVKMDLIDAMVAAADEKVSDDDLTRIEQAACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAYRKELFLEAGRRAVELCRRYYEQEDEGVLPRAIATKEAFENAMALDIAMGGSTNTVLHILAAAQEGGVDFTMDDIDALSRRVPCLCKVAPNKADVHIEDVHRAGGIMSILGELDRGGLLHRDTRTVHAPTLGAAIDQWDIGRSNAPEARELFLAAPGGVPTQVAFSQSSTWDTLDTDRETGVIRSVATPFSKDGGLAVLKGNLAPDGCIVKTAGVDESILVFAGPAKVFESQDAAVYGILNGGVQAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHASPEAASGGPIGLVREGDRIEIDIPNRTITLAVPEAELAARRAEQDAKGWKPAGPRKRKVSQALKVYAQFASSADKGAVRVLPE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GUAC_LIGS1
Sequence: MPVFDYEDIQLVPNKCIVKSRSEVNTKVKFGPMTFKIPVVPANMQTIIDENLAVWLAKNGYFYIMHRFYENERVDFVKNMHDKGLFASISVGVKPAEYDLIDELSQKNLVPEYITIDIAHGHSDTVINMIKHIKHKLPGVFVIAGNVGTPEAVRELENAGADATKVGIGPGKACITKLKTGFGTGGWQLAAIRACAKAASKPIVADGGIRNNGDIAKSIRFGASMCMIGSLFAGHDETPGDIIEKDGKKFKTYFGSASQYQKGEYKNVEGKKLLLPYKGKIADTLREMQEDLQSAISYAGGKELLALRKVDYVIVKNSIYNGDML
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: AGL86_ARATH
Sequence: MRSKIKLSLIANKTSRRTTFRKRKGGITNKLHELTTLCGVKACAVISSPYENPVVWPSTEGVQEAVSMFMERPATEQSKLMMSHETYLQDKITKETKKLESLRRENRESQLRQFMFDCVEGKMSEHQYGARDLQDLSLYIDHYINQLNSSVMLLTNNGASSSSFPPPLHTSVAGAGAGAGAAPLVVAGAGAAPLAVAGAGASPLAVAGVGAAPLAVAGAGPPMAQNQYEPIQPYIPTAFSDNIQYQAPVDFNHQIQHGIYDNLSLDPNHQYPFQDDPFMEMLMEYPYEQVGYAAEHAHIPFMNGNYYNYHQPPTVGLTTTGHMPSNNATTTTTTNTTVV
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Agamous-like MADS-box protein AGL86.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNAS1_CHEMY
Sequence: ETRYEKFLRQHVDYPRTAAPDTRTYCNQMMQRRGMTSPVCKFTNTFVHASAASITTICGPGGAPAGGNLRDSTASFALTTCRLQGGSQRPPCNYNGGTSTQRIRIACDGGLPVHYDRAI
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: FAC19_MYCTU
Sequence: MAVALNIADLAEHAIDAVPDRVAVICGDEQLTYAQLEDKANRLAHHLIDQGVQKDDKVGLYCRNRIEIVIAMLGIVKAGAILVNVNFRYVEGELRYLFDNSDMVALVHERRYADRVANVLPDTPHVRTILVVEDGSDQDYRRYGGVEFYSAIAAGSPERDFGERSADAIYLLYTGGTTGFPKGVMWRHEDIYRVLFGGTDFATGEFVKDEYDLAKAAAANPPMIRYPIPPMIHGATQSATWMALFSGQTTVLAPEFNADEVWRTIHKHKVNLLFFTGDAMARPLVDALVKGNDYDLSSLFLLASTAALFSPSIKEKLLELLPNRVITDSIGSSETGFGGTSVVAAGQAHGGGPRVRIDHRTVVLDDDGNEVKPGSGMRGVIAKKGNIPVGYYKDEKKTAETFRTINGVRYAIPGDYAQVEEDGTVTMLGRGSVSINSGGEKVYPEEVEAALKGHPDVFDALVVGVPDPRYGQQVAAVVQARPGCRPSLAELDSFVRSEIAGYKVPRSLWFVDEVKRSPAGKPDYRWAKEQTEARPADDVHAGHVTSGG
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension (PubMed:15042094, PubMed:15984864, PubMed:19182784).  Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols.  Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26-oyl-CoA.  It can also use 3beta-hydroxy-5-cholesten-26-oate (PubMed:24244004).
What are the official names of this protein?
Medium/long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase, FACL, Acyl-CoA synthetase, FACL19, Steroid-CoA ligase, Steroid-coenzyme A ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HEMA_INBSD
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALARPMCIGTIPSAKASILHEVRPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTHNVINAERAPGGPYRLGTSGSCPNVTSRSGFFATMAWAVPRDNKTATNPLTVEVPYICTKGEDQITVWGFHSDSKTQMKKLYGDSNPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: CARB_LISMF
Sequence: MPKRDDIKTILVIGSGPIVIGQAAEFDYAGTQACLSLKEEGYRVVLVNSNPATIMTDAEMADKVYIEPITLDFVSRIIRKERPDAILPTLGGQTGLNMAMELSAAGILDECNVEVLGTDLTAIKKAEDREAFRDLMNELGEPVPESDIIHNLDEAYTFVERIGYPVIVRPAYTLGGSGGGICHNEQELIETVTSGLKLSPVTQCLLEKSIAGFKEVEYEVMRDANNNAMVVCNMENIDPVGIHTGDSIVVAPSQTLSDREYQLLRDVSLKIIRALEIEGGCNVQLALDPDSYNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVRNPVTGTTFAHFEPTLDYVVAKIPRFAFDKFEQADRRLGTQMKATGEVMAIGRSWEEALLKAVRSLEIGADHLLLEEAENADEATLERKICFPEDDRLFFLAAALRRGQTIEQLHAKTKIDLFFLYKLSKTIELENRIKENPQNQEILAEAKRAGFSDAFLATCWNVDEQAIYDLRKAQNLFPVYKMVDTCAAEFESTTPYFYSTYEEENESTRSAKESVIVLGSGPIRIGQGVEFDYATVHSVWAIQQAGYEAIIINNNPETVSTDFSISDKLYFEPLTLEDVMHVIEIEQPLGVVVQFGGQTAINLADGLAKRGVKILGTSLEDTDRAENRDAFEKALEILQIPQPAGKTATSVEEAINVATDIGYPVLVRPSYVLGGRAMEIVESEEALKHYMTNAVKVNPKHPVLVDRYVSGQEVEVDAISDGENVLIPGIMEHIERAGVHSGDSIAVYPAQRLSSQVKNTIVDYTTRLATGLNIIGMLNIQYVVDGEEVFVIEVNPRSSRTAPFLSKITEIPMANVATRVILGENLIDLGYTPGLAPEKQEIFVKVPVFSFAKLRSVDTSLGPEMKSTGEVMGKDVTLEKALYKGFVASGTTMHDYGTVLLTVADRDKEEAVELAKRFNRIGFTIMATKGTASTLEEANIPVSQVKKIGENQETLIDYIRNGQVTLVVNTLTTGKRPERDGFQIRRESVENGIPVCTSLDTAEAILRVLESRSFELESMNASEVKQPKARV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RNC_STRPZ
Sequence: MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKDYKTCLQEFLQTKGDVVIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQDAAKNALAQLSEV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIHD2_DANRE
Sequence: MAIHGYDGKAALQQVNQFWSMLDDMCENNPEEYRSFIQRQMREGAEFHSPPQSHTCIRTAVLGANEGILYINICGWKRVPAPASDKEPVPVCGGRMEKLTEEKEEYSVVDAAFNPEVLQTTEKDKEEKENLCLLALNFIQQQHNLTLSQHYKLTNDKIKGSIRDTKQRLMSTKTCKSTLNGSQSEPAPSLLQQICSLQNTESDEDSSIELSIEQERKPARSGLIEVISSTELDQPQPQLPKHQLTICPDGNGSSRILQLCVELPGVRSVSQCQLRISEDDILLEVEDIYYLLLPFPELVKEETCTAKFNKKKQTLNVTVNVL
What are the official names of this protein?
PIH1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family.
Protein: MRAY_STAS1
Sequence: MVYLLAIIALLITFILVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLISIIITSILAIIFIDNSNPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIAIAVIFFILSQVFNLTDFSTGIHIPFINFEIPLSIAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFVMYAIMAYFQGATSIGLFCIIMIFALLGFLPFNLNPAKVFMGDTGSLALGGIFATISIMLNQELSLLFIGFVFVAETLSVMIQVTSFKLTGKRIFKMSPLHHHFELVGWNETKVVTVFWTVGLITGLIGLWIGVS
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_FRASN
Sequence: MRLVFAGTPAVALPSLRALLDSPRHQVVAVVTRPDRPAGRGRHQRSSPVRELADERGLEVLAPARASDPDFLARLGEIAPDCCPVVAYGALLPRPALDIPKHGWVNLHFSLLPAYRGAAPVQRAVLAGEDMTGASVFEIEPALDSGPVYGVLTERIRPTDTSGDLLDRLAVAGARLLEAVMDGIEDGTLQARPQPSDGVSLAPKLTVEDVRVDWSAPAAAVDRLVRAATPAPGAWTTFRDRRVKLGPVRPAPAGHPPLPSGRLAAPERGLVLVGTATTPVVLDEVRPEGKAPMPAADWIRGLRPGTDEAFA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.