PharMolix/UniProtQA huggingface dataset:
Protein: GLND_BURL3
Sequence: MSAHAAPSPEALSRRAEFKAAKTEMLERFRRAANVASLMHALSKLTDEALKRVWDDCGLPATLALVAVGGYGRGELAPYSDVDILVLLPDAHDPALDARIERFIGMAWDLGLEIGSSVRTVAQCIEEASQDVTVQTSLLEARRIVGSTALFERFTVHYHEALDARAFFTAKVLEMRQRHAKFQDTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDMLVFDLQTQAAESFGYEPTQAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGITRVLSPDRFVEKQGMLEIVDDGVFERHPDAILEAFLLYETTRGVKGLSARTLRALYNSREIMNNTWRRDPQNRDTFMRILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIGNFERPWVLYVAALFHDIAKGRGGDHSTLGMADARRFCREHGIASDDAALIVWLVQHHLTMSQVAQKQDTSDPEVIKRFAEVVGNERYLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRITLAVLGGANPDAHSELKSRQEQALALLRLETVPDDAHRTLWDQLDVGFFLRHDAADIAWQTRVLYRHVNAETAIVRARPSPIGDALQVLVYVKDRPDLFAGICAYFDRNGLSVLDARVSTTRHGYALDNFIVTQTERDVRYRDIANLVEQQLASRLTETAPLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRIGVHAARINTLGERVEDIFLLAGAGLSDNRLQIQLETELLRAIAV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MIME_PONAB
Sequence: MKTLQSTLLLLLFVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF
What is the function of this protein?
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
What are the official names of this protein?
Mimecan, Osteoglycin.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PSAJ_PARMW
Sequence: MQKFLTTAPVVAAIWFTLTAGILIEWNRFFPDLLFHPM
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RL9_TROW8
Sequence: MTRVILVQDVNGLGSVGDVVEVKAGYSRNYLVPKGMAVRWTEGAQKHIGDISAARRAREAAALQEARDIANTLTKEAVTRELRLAANAGEDGRLFGSVTAANIAKVLSSASGHKIDRGKIEIDSPIKTLGEHTVKVKLHPNVKVDINVVVYAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SUB2B_COCP7
Sequence: MKLLKSSLLLLLPFVTANPIPSEDKDIIPGRYIVTLKDGITQEDIEYHKSWVASVHRSNLAAATAAGRPRLETEGIRKFFQIHKMNAYSGAFDDQTAEDIRRNPYVKSVTPDRKVYLADTVVQENAGYNLGHMSSKGRHSFTYRYDSTAGEGIWAYVLDTGINVDHIEFEGRADSGYNAIKNVSNTDNFGHGSFTAGIIAAKTYGVAKKATVISAKAFDTGSSTYDYIFDAYNWVVKNITDSGRQKKSVVNMSISSAKYQPFDDAVDNAFEAGITTVVAAGNDQRDASNNTPASAANAITVASIRFDNGRSLFSNYGSVVDIFAPGERIVSCWIGGNNATRKADGTSVSSPHVAGLVAYLMAIEDLPDPAAVTKRVLDLSIPDLVRDPGEGSPNRIAYNGIQEMNETVIA
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease CPC735_003880.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: WCWK2_STREE
Sequence: MNKIDFVVTWVDGNDPVWKEKKSRYDGSVSTSKQSMNSVKAYREWGTFKYWFRGVERFAPWVNKVYLVTDQQRPSWLDINSEKLVLVDHTEIICNDCLPVFSANPIESNIHRIPGLSEHFVFFNDDMYLTAPVEPTDFFSEDGLPKYNTALSPIIPERYGTGNFQINDMEIVTSYFSRNEILKNGQFFDPKQGLKSIVKSLLYRNSQFICGFWESHLPYPLLKSTMDLIWEKEKAVLGRTSASRFRNPSDTNVWLFKYWQIASGQYAVGNPKLGRLFSLDNAGPDFWNLLNSGKYKIMCINDVYDIKDEEKVMQEFIAAMKNLLPDKSTFEL
What are the official names of this protein?
Capsular polysaccharide phosphotransferase WcwK, Stealth protein WcwK.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: MCE_VACCA
Sequence: MDVVSLDKPFMYFEEIDNELDYEPESANEVAKKLPYQGQLKLLLGELFFLSKLQRHGILDGATVVYIGSAPGTHIRYLRDHFYNLGVIIKWMLIDGRHHDPILNGLRDVTLVTRFVDEEYLRSIKKQLHPSKIILISDVRSKRGGNEPSTADLLSNYALQNVMISILNPVASSLKWRCPFPDQWIKDFYIPHGNKMLQPFAPSYSAEMRLLSIYTGENMRLTRVTKSDAVNYEKKMYYLNKIVRNKVVVNFDYPNQEYDYFHMYFMLRTVYCNKTFPTTKAKVLFLQQSIFRFLNIPTTSTEKVSHEPIQRKISSKNSMSKNRNSKRSVRSNK
What is the function of this protein?
Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities.  Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation.  At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap.  At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail.  In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase regulatory subunit, Poly(A) polymerase small subunit, PAP-S, VP39.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Poxvirus/kinetoplastid 2'-O-MTase family.
Protein: PRP19_DICDI
Sequence: MICAISGSTTEEPVISTKTGNVYEKRLIEKYIDTNGKEPTTGEPLGLSDLITVKIGKTVKPRPTTATSIPSMLQLFQNEWDSLMLETFTLKQQHETVRQELAHSMYQYDAACRVIARLVKERDAARSALANARNIVQQQQQQTNNNNNNNNNKDVEMSSASTPSSSEDNLLDSTIYKRIAEKSEELIKTRKERTHQSLAEPDAIKQFKVSANVETDCQIKSLEVNSQDNNLIAMGGINGNVYVYSRETNELCTAIKGTSSAPINKVLFAPNNTIVSAGSDAVIRVVKGGESPSKKTYTQYKSTYQFAHKASVTDISLHVLGDYIISSSLDKSLNMYDIVNGTHLTSFGQSQQLCYTSVAFHPDGMFFAAGTQNGVVKIFDLKSKVNSFNFQGLSTAVNCISFSENGYYLTAADNNTVKLFDLRKAATKNSPDIQTITLDNQQIKSINFDYSSQYLGVASSNQINLYSCKSKQKPPISSIHSIDSDCLDFKWARPNSNFFVTSSSSKNIVNIFSN
What is the function of this protein?
Probable ubiquitin-protein ligase mainly involved in pre-mRNA splicing and DNA repair.  Core component of the Prp19 complex/PRP19C/Nineteen complex/NTC which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity.
What are the official names of this protein?
Pre-mRNA-processing factor 19, PRP19/PSO4 homolog, RING-type E3 ubiquitin transferase PRP19.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRP19 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm.
Protein: MRAY_SHISS
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 1433E_RAT
Sequence: MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm.
What are the official names of this protein?
14-3-3 protein epsilon, 14-3-3E, Mitochondrial import stimulation factor L subunit, MSF L.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Melanosome.
Protein: RL7_BURMA
Sequence: MAIAKEDILAAVEGMTVLELNELVKAFEEKFGVSAAAVAVAGPAAGGAAAAAEEKTEFTVVLAEAGSNKVAVIKAVREITGLGLKEAKDLVDGAPKPVKEGVDKASADEAKKKLEDAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TAT_HV1B1
Sequence: MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQSRGDPTGPKE
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: PHNW_BURM7
Sequence: MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFTPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: PE191_ARATH
Sequence: MANSHTDDLDELLDSALDDFKDLNLSHQRNQREAQEEEEKKRKEETVLLPSGVQGLGMGLPDMRSKKRGKQKVSKEDHVAEALDKLREQTRETVKGLESISSKQLPASDDDGMVEDFLKQFEDLAGSKDLESIVETMMQQLLSKDILHEPMKELGARYPKWLKENEASLSKEDYKRYSQQYKLIEELNAVYENEPNNSSKIMEIMQKMQECGQPPSDIVKEIDPGFDFASLGQISPEMLESSPNCCIM
What is the function of this protein?
Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins (PubMed:16923726, PubMed:17478547).  Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs) (PubMed:16923726, PubMed:17478547).  Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane (PubMed:17478547).  Required for transport of APEM9 to peroxisome membranes (PubMed:21487094).  Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer (PubMed:17478547).
What are the official names of this protein?
Peroxisome biogenesis protein 19-1, Peroxin-19-1, AtPEX19-1, Peroxisomal membrane protein import receptor PEX19-1.
What is the protein family that this protein belongs to?
Belongs to the peroxin-19 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Lipid-anchor. Note=Predominantly cytoplasmic.
Protein: ACKA_DESVH
Sequence: MNVLVINSGSSSIKYQLIDMEREVPLCSGLVERIGEPMGKLTHKIRPDAEGEEKLTFEQPFTNHVEGMKRVVELITDADKGVIKDKSEIGAIGHRVLLGGEEIKQSVRIDDWAKGVIRDYIPLGPLHNPANLAGIEVAEELFPGLPNVGVFDTEFHQSMPAKAYLYPLPIELYEELKIRRYGFHGTSHRYITKRTAQYLGKPLDELNIITCHLGNGCSMAAVKNGKCVDTTMGITPLEGLMMGTRCGDIDPAIVPFLMEKKNLSPAEADTLMNKQSGLKGMCGMNDMRDLHAARENGNERAQLAFEMFTYRIKKYIGAYYAVLGRVDAVVFTAGIGENDDFVRAEVCAGLDSLGIAVDPARNAVRNGQPRHISPDGSRVAVLVVPTNEELEIAQATLDVLKG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_AERS4
Sequence: MAKQIQAIRGMNDCLPEQSPVWQKVEQILRQVVASYGYSEVRMPIVEQTHLFKRAIGEVTDVVEKEMYTFEDRNGDSLSLRPEGTASCVRAGIEHGLLYNQERRMWYMGPMFRHERPQKGRYRQFHQFGVELFGINGPDIDAELIMLTHRLWRLFGISDHVTLQLNTLGQSSERAAYRDALVAYLEQYKDQLDEESQRRMYSNPLRVLDSKDERVQAILVKAPRLFDHLGEESLAHFEGLKRLLESAGIKYEVNERLVRGLDYYNLTVFEWVTTSLGAQGTVCAGGRYDGLVEQLGGQATPAVGFAMGMERLVLMLETLELNADIRPAVDVYLAMVGEGSEQAGFQLAERLRDALPDLRLMSHCGGGNFKKQLKRADKSGAAIALILGETEVQNGEITIKYLRGQAEQQTVTVDAAIALLAAKGD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP1_PONAB
Sequence: MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.  In the SCF complex, serves as an adapter that links the F-box protein to CUL1.  The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.  SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.  SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.  SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.  SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.  SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1.  SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.  SCF(FBXW2) directs ubiquitination of GCM1.  SCF(FBXO32) directs ubiquitination of MYOD1.  SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5.  SCF(FBXO33) directs ubiquitination of YBX1.  SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53.  SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription.  SCF(CCNF) directs ubiquitination of CCP110.  SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2.  SCF(FBXO9) directs ubiquitination of TTI1 and TELO2.  SCF(FBXO10) directs ubiquitination of BCL2.
What are the official names of this protein?
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: TCPQ_CAEEL
Sequence: MAMKIPKSGYNRFMKEGAQHFKGTDEAVQRNIEACTELASQIRSAYGPNGMNKMVINHIEKLFVTNDAATILKELEIQHPAARIIIMATEMQEKQIGDNTNTVVILAAALLEHAANLIHMGMTPQEVAAGYEQAAEKALEILPTLVVKEATDMKNIEEVRQYIRSAITSKQYDNEDIIADLVAKACVTTCPANSFNFNVDNIRICKIIGSGVHTSTVMNGMVFKRGAEGEIREARDARIAVYTCPFDLTQTETKGTVLIENADELRNFSKGEEAEVEEQVKAIADNGVKVVVAAGKFGDMYLHFLNKYKIMAVRLTSKFDLRRLCRTVGAQPQARICAPAVNLLGHCDSVAVQEIGDENVVVFDKKSETGKVATIIIRGSSQSRIDDVERAVDDAVNTYKALTKDGKLLAGAGAVEIELAKEIESFGAKAPGLEQYAIKKFAHALETLPKAIAENAGMPTTETLTKLYAEHVAGKKNAGIDIWKRETMDAVVNNIFDLYAGKRLAIKLATDAASTILKVDQIIMSKQATGGPKPRGPKAQDEDDDGMA
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).  Required for correct subcellular localization of pgl-1.
What are the official names of this protein?
T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_SYMTH
Sequence: MRLSDFDYDLPKELIAQKPVEPRDASRLMVVHRASGAIEHRCFRDLPEYLRPGDGLVINETRVMPARLLGSREQTGGAMEVLLLKRLDRDRWETLVKPGKKARPGERIVFGDGLLVGTVVGPTDYGGRVIDFHYEGVFENLLERLGQMPLPPYIHEQLEEPERYQTVYAREWGSAAAPTAGLHFTAELLDRLAARGVEIHRITLHVGLGTFRPVEVEDPTQHKMHSEFYHVSPEAAAGINAVRKGGGRLVAVGTTSVRTLETVADEDGTVRPGEGWTDIFIYPGYRFKAVDALVTNFHLPKSTLLMLVSALAGHDLIMRAYREAVAQRYRFFSFGDAMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3578_PSEAE
Sequence: MQLEFHQVDAFSSRPFSGNPAVVYRLDAWLADELMQMIATEHNLSETAFVVREGEAWRIRWFTPSVEVALCGHATLAAAHVLFEVYDEPGERLEFISRSGALRVNREDERLVLDFPAQYPSEVGSTVELEQALGLPPVDVLGSTDKLLVLLESEEAVRACRPDFAALARLPWRGVIVTARGLQKDFVSRFFAPAMGVDEDPVTGSAHCSLIPYWAQRLNKLSLTAQQCSARGGELWCRLEGERVSIAGHAVLVASGRIRLS
What are the official names of this protein?
Uncharacterized isomerase PA3578.
What is the protein family that this protein belongs to?
Belongs to the PhzF family.
Protein: ARP5_DROPS
Sequence: MGSPKRVLVIDNGSYECRVGWNNTKEPALRFRNVLTKPRKDRKKEAIPDTTDGAPTPVAAEVPAEIQVGNDITNIEAVRAHLKSPFERNIITNWNHQEQIFDYIFTKMGFEGEQSIANPIVLTEALANPNFCRQNMSELLFECYGIPAVSYGIDALYSWEHYQNRRKKVSDALIISLGYSTTHVIPVLNGKLQLQHVRRLNVGGYHIITYLLCLMQMKYPVHLNAISISRMEKLVHEHCHIAVDYREELLKWGQMDYYEEHIMKIQLPYNPVTATNALLTAEQKLEKRRELAMRLLEIKNRREGEKLLEDEQQLFVYNKLRQLYEQDKLQKFELALAQQQIGNLDELDSLISTISNRIKRIKERPLSSPKPSKQQEKIDKMPKAPEGVSQADWLAELQSKREQLLQRKQTRQQQRQEQGKRHTHAAQERMRIISTLARSEKRRKANGEEEDDGFGMNDNDWDVYKRINRYNDDSDSDADNEQLLEFEKILSHYDVNFDDGNAVQTQSAAENYQLHFGVEDIRVPEILFQPSMIGSPEAGLAELIAFVLKLFTAQEQQRMVEHVYLTGGCAQFRGLKERLAREFLEMRPFQSKFSIYESDDHTLSAWLGACVQASQPNFGQTLTTRKDYQEHGSEYFREHRASNLFYPTPKD
What is the function of this protein?
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
Actin-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMA_CHLTB
Sequence: MTLLILLRHGQSVWNQKNLFTGWVDIPLSQQGIQEAIAAGESIKHLPIDCIFTSTLVRSLMTALLAMTNHSSQKVPYIVHEERPDMSRIHSQKEMEQMIPLFQSSALNERMYGELQGKNKQEVAAQFGEEQVKLWRRSYRIAPPQGESLFDTGQRTLPYFQERIFPLLQQGKNIFISAHGNSLRSLIMDLEKLSEEQVLSLELPTGQPIVYEWTGQKFTKHAPSLG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: H1623_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDESRMEMQEKTEQGKSYLDFAENLLPQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.23, HNTX-XVI.23, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VP24_MABVR
Sequence: MAELSTRYNLPTNITEKSINLDLNSTARWVKEPSVGGWTVKWGNFIFHIPNTGMTLLHHLKSNFVVPEWQQTRSLFSHLFKNPKSTIMEPFLALRILLGVALKDQELQQSLIPGFRSIVHMLSEWLLLEVTSAIHISPNLLGIYLTSDMFKILMAGVKNFFNKLFTLHVVNDHGKPSSIEIKLTGQQIIITRVNMGFLVEVRRIDIEPCCGETVLSESVVFGLVAEAVLREHSQIERGQPLNLTQYMNSKIAI
What is the function of this protein?
May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding.  Unlike Ebola VP24, mVP24 has no measurable impact of host dendritic cell function.
What are the official names of this protein?
Membrane-associated protein VP24, Marburg VP24, mVP24.
What is the protein family that this protein belongs to?
Belongs to the filoviridae membrane-associated protein VP24 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and to the plasma membrane where budding takes place (By similarity).
Protein: PGK_PROM4
Sequence: MAKRSLSSLSAEELCGKRVFVRVDFNVPVNAEGDITDDTRIRAALPTIKDLIDKGARVILSAHFGRPKGQVNDAMRLTPVAQRLSELLGHTVIKTDSCIGSDAQAKAQSLNNGDVMLLENVRFIQGEEKNDPDFAKELSELAEVYVNDAFGAAHRAHASTEGVTKFLSPNVAGYLMEKELQYLQGAIDSPKRPLAAIVGGSKVSSKIGVLESLIDKCDKVLIGGGMIFTFYKARGLSVGKSLVEDDKLELAKALEEKAKSKGVELLLPTDVVLADNFSPDANSQIAQINSIPEGWMGLDIGPDSVKLFQDALEDCQTVIWNGPMGVFEFDKFANGTNSIATTLSVLSQKGCCTIIGGGDSVAAVEKAGLADKMSHISTGGGASLELLEGKTLPGVAALDELD
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.