PharMolix/UniProtQA huggingface dataset:
Protein: NUOD_LEPBP
Sequence: MVMYEKTAEHFGQKFKDLPEGHLLVNLGPSHPATHGILQNVIQIDGERVVDTESVIGYVHRCFEKLGERYDYNQFLVCTDRMNYVSTPLNNIGWILTVEKMMQIQVPDRVTYVRMIISELSRIMDHIICNGIMGVDLGAFSGLLHLFHHRENIYQILEKLTGARLTTTFCRVGGMERDIYPEFQTEIKLILKGLKPALDEFEELLIRNKIFNERTKGIGGISADRAIAYGFSGPNLRAAGVPWDVRKDDPYMFYDKVNFDIPVGEDGSALDRTLVRMEEMRQSMKIIEQLIDGIPEGPYHADVPHSFLPPKDRVYHNMEELIYHFKIIMHGVKVPPGEYYHATEAANGELGFYVVSEGDKSPWRVHVRRPCFWYYQAFPEMVKGGLLADTIATMSSLNVIAGELDC
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BGALB_ASPNC
Sequence: MTRITKLCVLLLSSIGLLAAAQNQTETGWPLHDDGLTTDVQWDHYSFKVHGERIFVFSGEFHYWRIPVPGLWRDILEKIKAAGFTTFAFYSSWAWHAPNNHTVDFSTGARDITPIFELAKELGMYIIVRPGPYINAEASAGGFPLWLTTGDYGTLRNNDSRYTEAWKPYFEKMTEITSRYQITNGHNTFCYQIENEYGDQWLSDPSERVPNETAIAYMELLESSARENGILVPFTANDPNMNAMAWSRDWSNAGGNVDVVGLDSYPSCWTCDVSQCTSTNGEYVAYQVVEYYDYFLDFSPTMPSFMPEFQGGSYNPWAGPEGGCGDDTGVDFVNLFYRWNIAQRVTAMSLYMLYGGTNWGAIAAPVTATSYDYSSPISEDRSISSKYYETKLLSLFTRSARDLTMTDLIGNGTQYTNNTAVKAYELRNPTTNAGFYVTLHEDSTVGTNEAFSLRVNTSAGNLIVPRLGGSIRLNGHQSKIIVTDFTFGSETLLYSTAEVLTYAVIDKKPTLVLWVPTDESGEFAVKGAKSGSVVSKCQSCPAINFHQQGGNLIVGFTQSQGMSVVQIDNDIRVVLLDRTAAYKFWAPALTEDPLVPEDEAVVLIQGPYLVRSASLEKSTLAIKGDSINETAVEIFAPENVKTITWNGKQLKTSKSSYGSLKATIAAPASIQLPAFTSWKVNDSLPERLPTYDASGPAWVDANHMTTANPSKPATLPVLYADEYGFHNGVRLWRGYFNGTASGVFLNVQGGSAFGFSAYLNGHFLGSYLGNASIEQANQTFLFPNNITHPTTQNTLLVIHDDTGHDETTGALNPRGILEARLLPSDTTNNSTSPEFTHWRIAGTAGGESNLDPVRGAWNEDGLYAERVGWHLPGFDDSTWSSVSSSSSLSFTGATVKFFRTTIPLDIPRGLDVSISFVLGTPDNAPNAYRAQLFVNGYQYGRFNPYIGNQVVFPVPVGVLDYTGENTIGVAVWAQTEDGAGITVDWKVNYVADSSLDVSGLETGELRPGWSAERLKFA
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Probable beta-galactosidase B, Lactase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIFK_PYRCJ
Sequence: MTELYCERKTLADLIAFASVEGLPVGEAAKRLCMSRQGAYKAVKALREAGYLSEGPVIKLTQKGRDALSIVLRNLLRYFDIASIKLVGRVVTGLGEGAFYMSLEGYRRAIERELGFTPYPGTLNIKLEPQSLAHRRYLDGLPGIHIPGFTNGMRTYGAVKAFRARLADVEGAVVMPERTHHPVDVIEFIAPVRVRDVLGLKDGDRVELEVYL
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: PG137_MONPV
Sequence: MTTVPVTDIQNDLITEFSEDNYPSNKNYEITLRQMSILTHVNNVVDREHNAAVVSSPEEISSQLNEDLFPDDDSPATIIERVQPHTTIIDDTPPPTFRRELLISEQRQQREKRFNITVSKNSEAIMESRSMITSMPTQTPSLGVVYDKDKRIQMLEDEVVNLRNQRSNTKSSDNLDNFTRILFGKTPYKSTEVNKRIAIVNYANLNGSPLSVEDLDVCSEDEIDRIYKTIKQYHESRKRKIIVTNVIIIVINIIEQALLKLGFEEIKGLSTDITSEIIDVEIGDDCDAVASKLGIGNSPVLNIVLFILKIFVKRIKII
What is the function of this protein?
Required for viral crescent formation early during virus morphogenesis.
What are the official names of this protein?
Protein OPG137.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG137 family.
Protein: AAT_SULTO
Sequence: MPVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSLDEGFTGYTSAYGIDELRQKIAEHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEVIIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSELESKINKKTKMIVLNNPHNPTGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSKTFSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKKRRDIMYEELKKIKGIQVHKSQGAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGEVFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFAT_MOUSE
Sequence: METRTAENTAIFMCKCCNLFSPNQSELVTHVSEKHGEEGVNVDDVIIPLRPLNTPENPNPSKGGDEFLVMKRKRGRPKGSTKKPSTEEEVVENLVSPSEDGPLATEEGSRLAPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEDGDAGNESDLDLEKTYKEDDREKASKRPRAQKTEKVQKISGKEAGQLSGAKKPIISVVLTAHEAIPGATKIIPVEAGPPETGAPPPETTAADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDMHDPQDKKVKEALDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCALCLKKFVSSIRLRSHIREVHGAAQETLVFTSSINQSFCLLEPGGDIQQEALGDQLQLAAEEFVCPEIDVRKEEACPGEAQPEVGLRELVVPGDAHAPPPGPLATPQSESSSLSPCKLETTVVSSDLNSLGVVSDDFLLKSDTSSAEPPAAAEATSDTQHRDSAQTQGEEVTLLLAKAKSAGPDPESSPGGRQKVGALPASESDSSTCLRANPTEASDLLPTVTDGGDLGVCQPDSCTPSSEHHPGSTAFMKVLDSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTELDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMNTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTSDGKQFKCTVCDYTAAQKPQLLRHMEQHASFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYTNVGSGELAAEALIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWEPAAETPEEPSTQYLYITEAEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGSETHDAAAVASVVAMAPGTVTVVKQVTDEEPSSNHTVMIQETLQQASVELAEQHHLVVSSDDVEGIETVTVYTQGGEASEFIVYVQEAVQPVEEQVGEQPAPEL
What is the function of this protein?
May be involved in transcriptional regulation.  Overexpression causes down-regulation of a number of genes involved in the immune response.  Some genes are also up-regulated.
What are the official names of this protein?
Zinc finger protein ZFAT, Zinc finger protein 406.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: LEXA_ALTMD
Sequence: MRPLTARQTEVLELIKTTMQETGMPPTRAEIARQLGFRSANAAEEHLKALARKGVIEILPGTSRGIKLNIPLDNEAEEEEGLPLIGRVAAGEPILAQEHVESHYKVDPALFQPQADFLLRVNGMSMKDIGILDGDLLAVHRTTDVHNGQVVVARVDEDVTVKRLEKRGREVLLHAENEEFSPIKVDLANEPFAIEGIAVGVIRNADWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MDTD_SALSV
Sequence: MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLLHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_METMJ
Sequence: MDEEEIKYFVRVRNTDLDGTKAVHIALTGIKGIGPHTSRTITALAAVDPHAILGKLDDESVGRIANAVDTYTEQVPDWMVNRQKDVYTGEVRHLLGTDLTMMNDDDVNRMRKMRSYRGIRHETGQKVRGQRTKSTGRTGTTVGVKRKKD
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IHFA_BRUC2
Sequence: MGGKTVTRADLAEAVYRKVGLSRTESAALVEMILDEVCDAIVNGETVKLSSFATFQVRDKNERIGRNPKTGEEVPILPRRVMTFKASNVLKQRILQEHQKRQGKTSK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PDE1C_HUMAN
Sequence: MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK
What is the function of this protein?
Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:8557689, PubMed:29860631).  Has a high affinity for both cAMP and cGMP (PubMed:8557689).  Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials.  Regulates smooth muscle cell proliferation.  Regulates the stability of growth factor receptors, including PDGFRB (Probable).
What are the official names of this protein?
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, Cam-PDE 1C, Hcam3.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
What are the subcellular locations of this protein?
Lysosome.
Protein: MRNC_GLOVI
Sequence: MDPVQIRSLSLEALAYLGDAVWELHVRTRVLLPPRRLQWLHGDTVACVRASAQAKLATCLSPHLTVEEADWLRRGRNAGGTVPRRLDPATYRLATAFEALLGYLFLADRDRLGVILHLCDEFQHHHGPDTPSPEA
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFB_METV3
Sequence: MDNFELRLNSGKLIDNDSKVHEIGVIAMGSYLENHGSALPIDTDIKIASYVALNVALTTGAKFLGTVCTATEYDYIKHGIHNSLEDILEELEEIIIKYSKIGVNKFLIINCHGGNSDVSKKIEQLQEKIRNNFKEYGTTEKELEYIKKIKYNFKEYGNTEKINIKIKSFGYIHAYSEELSIGKCIGIYDETKFNKHTPENYGEIGMVGLPEARLNNKYIDKEAKMVESIPAVVNEQYGEELIKKMVNESIEYIREFLMLK
What is the function of this protein?
Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
What are the official names of this protein?
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, FAPy deformylase, Formamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily. FAPy deformylase family.
Protein: DF276_ARATH
Sequence: MSGQKYQLVSLLLIICLLFSQSTASGCNFKGSCRTDDQCKRICRGHGLDPSFQLCVPYSSKGGKCCCLHYEGAPLSSEVI
What are the official names of this protein?
Defensin-like protein 276.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: JAG1B_DANRE
Sequence: MILRRSSVFSAFYLHAFLLCLRTTVSDASGHFELEILSMQNANGELQNGACCDGARNPADRKCTRDECDTYFKVCLKEYQSRVSSAGACSFGTGSTPVLGGNKFSTKGTRSEKSRIVLPFSFAWPRSYTLIVEALDFNNETASESGKLIEKAYHSGMINPNRQWQRLTHNGPVAQFEYQIRVTCLEHYYGFGCNKFCRPRDEFFGHYTCDQNGNKTCLEGWTGPDCNTAICRQGCSTEHGSCKQPGGCKCLYGWQGPYCDKCIPHPGCVHGTCVEPWQCLCDTNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCEDGYSGVNCERAEHACLSNPCANGGTCKETSQGYECHCAIGWSGTSCEINVDDCTPNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECEDKPCVNAKSCHNLIGAYFCECLPGWSGQNCDININDCKGQCLNGGTCKDLVNGYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYCKPNPCQNGAQCFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDSCTVAVASNSTPEGVRYISSNVCGPHGRCRSQAGGQFTCECQEGFRGTYCHENINDCESNPCRNGGTCIDKVNVYQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQCDEATCNNGGTCHDEGDTFKCRCSPGWEGATCNIAKNSSCLPNPCENGGTCVVNGDSFNCVCKEGWEGSTCTENTNDCNPHPCYNSGTCVDGENWYRCECAPGFAGPDCRININECQSSPCAFGSTCVDEINGYRCLCPPGRIGPDCQEVVGRPCIANGQVTADGAKWEEDCNICQCQNGRIHCTMMWCGPKSCRIGKARGGCPASQSCVPIKEEQCFVKPCPSLGECWPSAPPPPSKCHASFSYQDDSCANITFTFNKENMPQGLSVEHVCNELRHWYLLKNLSTEYAVSISCEPSSSASNEIHISISTEEPRTDRSPIKDITVQIIDLVSKHNGNSTIIKAITGVRVHQIPSPKTDYLVPLLSSIFIVLWIFALASAFLWCIHRRRKQNTHSNTATSATEDNTTNNVREQLNQIKNPIEKHAAHGVPIKDYEGKNSIIAKIRTHNSEVEEEDMDKHLQKARFTKQPAYTLVEREERAPNKNPNWTNKQDNRDLETAQSLNRMEYIV
What is the function of this protein?
Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity).  Seems to be involved in cell-fate decisions.
What are the official names of this protein?
Protein jagged-1b, Jagged1b, Jagged3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane.
Protein: RL1_HALMA
Sequence: MADQEIENAVSRALEDAPERNFRETVDLAVNLRDLDLNDPSNRVDESVVLPAGTGQETTIVVFAEGETALRAEEVADDVLDEDELEELGGDDDAAKDLADDTDFFIAEKGLMQDIGRYLGTVLGPRGKMPEPLDPDDDVVEVIERMKNTVQLRSGERRTFHTRVGAEDMSAENIADNIDVILRRLHADLEKGPLNIDTVYVKTTMGPAMEVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1, HL8, Hmal1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LEUC_DESOH
Sequence: MGKTIAQKIFDAHSVDQPFGEVHVIRLDGVFCHEITTPTAICDLMEKNKDRVFDPSKIKAVIDHVTPAKDSKTAAQGKILRQWARRHGIDGFFDIGRNGVCHALFPEQGFVRPGHTIIMGDSHTCTYGAFGAFAAGVGTTDLEVGILKGVCALNYPSTIKVVLNGKLSPGVYAKDVILAVIAELGVNGATNRVIEFTGPCVDAMSMEARMTLCNMAIEAGGTCGICYPDKTTVAYLWEFIKGEYPSRQAALKAFKKLVSDPDADYDRVLEMDISDLSPRVTYGYKPDCVKPVAEMEGTPIDQVYIGSCTNGRLEDLRVAAKVLKGKKVHPSVRGIVSPATPTVFQAALEEGLIATFMAAGFCVTNPTCGACLGMSNGVLAPGEVCLSTTNRNFNGRMGKGGMVHLASPATAAAGAIAGCITNSKLYKKRAE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: SYP_CAMJE
Sequence: MMRFTKFYAPSLKEAPKDASLPSHIFLTRAGFVEQIGSGLYNFLPLGKRVLDKIKNIVKEEMDKAGAQEVNLSFITPASLWQESGRYNVFGKELLRFKDRKENEFVLGPTHEEAMLSLVKNKITSYKQLPLHLYQIGLKFRDEARPRFGLLRCREFLMKDGYSFHANEEDLGREFELMYKTYSQILQRMGLDFRAVEADSGAIGGSGSKEFMVLAKNGEDDILICENCDYAANVEAAKRAKKTCQDERPEANYASKFHTPNIKTIDSLAQFFKINAFYTIKAVVKKAIYENESKLVVFFIRGSDDLQEVKAQNTCSALELVDASEEELKKAGLVAGFIGFVGLKDIDFYIDFELENEKQMIMGANEKDYHLIGIDVVNLNKDRFKDLIEVKEGDCCVKCGAKLKQSKGIEVGHIFKLGQKYSKAMNANFLDENGKSQPFYMGCYGIGVSRLLAVAIEANHDEKGCIWNKTLAPFVLEIIVSNLKDEKALEFANKLYRDLTNLGLEVLLDDRNERFGVKMNDFELMGFPYALVIGKGLENNEIELIQREGLVKELIKTDELMEILKKKVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHB_METSB
Sequence: MQLTLWTYEGPPHVGAMRVAAAMKDVHYVLHAPQGDTYADLLFTMIERRESRPPVTYTTFEARDLGGDTAALFQRTAQEAYERFKPKALLVGSSCTAELIQDDPGGLARGLGLPVPVIPLEFSAYQRKENFGASLTFYNLVRAFAKALATPRATRSAARPSCNLLGATALGFRHRDDIREVTLLLDRLGVGVNICAPLGASPDDLARLPEADFNIVLYPEVALEAAEWLKRTHRQPLVKTQPIGVGATHAFIEEVARLAGLDPRPLLGPAESRLEWYSRSVDSTYLTGKRVFIFGDATHAIAAARVASRELGFTVAGLGSYSREFAREMRAAAALYSLNALITDDYLEVEAEIERLQPELVLGTQMERHIAKRLGIPCAVISAPVHVQDFPARHSPQMVFEGANVIFDSWVHPLMMGLEEHLLTMFRGDEEFHDEAAPSHLGVAVATAQATHTPAILAWDAGAERELKSIPFFVRGKARRNTERYAQERGLPLITIETLYDAKAHYSR
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: RL4_METTP
Sequence: MNAKIIDISGNPVGEIVLPAIFDEEYRPDLIKRAVLAAQANRLQPYGPHFYAGMNTSARSWGPGHGVSRVPRIVTGRRAAAVPMARGGRASHPPVPSKVLSEKINEKERIKAIRSAVAATAKPDIVAARGHLFSGELPIVVRGEIESISKTSELRRFLMAAGLWDDVMRAKNGRKVRAGKGKIRGRRFRQPRSILIVAAADNGIGRAARNLPGVDFVTADRLNAELLAPGTHAGRLTVWSEPSLKVLEERL
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PRR13_HUMAN
Sequence: MWNPNAGQPGPNPYPPNIGCPGGSNPAHPPPINPPFPPGPCPPPPGAPHGNPAFPPGGPPHPVPQPGYPGCQPLGPYPPPYPPPAPGIPPVNPLAPGMVGPAVIVDKKMQKKMKKAHKKMHKHQKHHKYHKHGKHSSSSSSSSSSDSD
What is the function of this protein?
Negatively regulates TSP1 expression at the level of transcription.  This down-regulation was shown to reduce taxane-induced apoptosis.
What are the official names of this protein?
Proline-rich protein 13, Taxane-resistance protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: LFTR_SHISS
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGAPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWHEDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFISHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_RALSO
Sequence: MPREIAMYNLPDAHGHFGPYGGTFVAETLSHALDELRDAYARYQHDPEFIKEYEYELKHFVGRPSPIYHARRLTEHCGGAQIYLKREDLNHTGAHKVNNVIGQALLARRMGKPRVIAETGAGQHGVATATIAARYGMECVVYMGSEDVRRQAANVYRMKLLGATVVPVESGSRTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGEECKVQMPELAGRQPDAVIACVGGGSNAMGIFYPYIDHASVQLIGVEAAGEGLESGRHAASLTGGSPGVLHGNRTYLLQDEDGQIIETHSISAGLDYPGVGPEHAWLKDAGRAQYVGITDKEALQAFHDLCRMEGIIPALESSHALAYACKLAPTLPKDKILLVNLSGRGDKDMHTVAELSGIDL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RS21_SHEPW
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAIKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SYFA_GLOVI
Sequence: MQQQLDALQLEALKAIREAADLTILERIRVDFLGKKGKLSALLGGMARLPAEERPVVGALVNQVKARVEEALAAQQTHLQDQLIELRLVAEALDVTMPGRFVPPGRLHPLTATTDRIVDVFVGLGFTVASGPQIETEYYNFEALNTPADHPARDMQDTFYLSDGLVLRTQTSSVQIRYMEENDPPVRICVPGRVYRRDQVTNRHSPVFHQLELLAVDEEITFGDLKGTLTFFTQEMFGDRPVRFRPSFFPFTEPSAEVDVQCRFCDGKGCRTCSHTGWLEIAGCGMVDPNVFQAVGYNPEKVQGFAAGMGIERIAMLLYDINDIRLFYTNDLRFLRQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_DESRM
Sequence: MSIRVRFAPSPTGPLHIGGARSALFNWLYARHHGGQFLVRIEDTDMERSSRESEENILNALRWLGIDWDEGIEVGGPNGPYRQTERLDIYRQLAKELVDAGHAYYCYCSEEELAVEREALMEKGELPRYLGRCRNLCPEDKAKFEAEGKKPVLRFRVPENQTITINDHVRGQVEFESNGIGDFIIMKSDNIPTYNFAVVVDDHDMGITHVVRAEEHLSNTPRQILIYEALGWQKPEFAHISLILGKDRSKMSKRHGATSIEQYHNLGYLPEALVNFLALLGWSPGGEEEIFTLKEIKEQFTLDRVAKNPAVFDIDKLNWLNGHYIRQASVERLTKLAVPYLQGAGYLKEEISTEKMAWLEQVVAIARNYISYMQEITQHVDVFFRDNVEITEEDAKQVQGWEQMPVVMKAAHELFSAANELTEESVKAIIKAIGKQTGLKGKFIFQPLRVGITGQTHGPELHQIIPVIGKERTLARLEAALK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN800_HUMAN
Sequence: MPLRDKYCQTDHHHHGCCEPVYILEPGDPPLLQQPLQTSKSGIQQIIECFRSGTKQLKHILLKDVDTIFECKLCRSLFRGLPNLITHKKFYCPPSLQMDDNLPDVNDKQSQAINDLLEAIYPSVDKREYIIKLEPIETNQNAVFQYISRTDNPIEVTESSSTPEQTEVQIQETSTEQSKTVPVTDTEVETVEPPPVEIVTDEVAPTSDEQPQESQADLETSDNSDFGHQLICCLCRKEFNSRRGVRRHIRKVHKKKMEELKKYIETRKNPNQSSKGRSKNVLVPLSRSCPVCCKSFATKANVRRHFDEVHRGLRRDSITPDIATKPGQPLFLDSISPKKSFKTRKQKSSSKAEYNLTACKCLLCKRKYSSQIMLKRHMQIVHKITLSGTNSKREKGPNNTANSSEIKVKVEPADSVESSPPSITHSPQNELKGTNHSNEKKNTPAAQKNKVKQDSESPKSTSPSAAGGQQKTRKPKLSAGFDFKQLYCKLCKRQFTSKQNLTKHIELHTDGNNIYVKFYKCPLCTYETRRKRDVIRHITVVHKKSSRYLGKITASLEIRAIKKPIDFVLNKVAKRGPSRDEAKHSDSKHDGTSNSPSKKYEVADVGIEVKVTKNFSLHRCNKCGKAFAKKTYLEHHKKTHKANASNSPEGNKTKGRSTRSKALV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 800.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.