PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_CUPPJ
Sequence: MASTTSRSARPARRNNKASGNTTPLLWMAFALLVVVLDQFFKIVIVRTFTYGESRPVTRFFNLVLVYNKGAAFSFLADAGGWQRWFFTGLGLVVGAFIVWLLYRHTGQKLFCFAVSLILGGAVGNVVDRVVYGHVIDFLDFYVRNYHWPAFNVADCAITVGAVLLIVDELRRVRKH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HRURF_HUMAN
Sequence: MAQPTASAQKLVRPIRAVCRILQIPESDPSNLRP
What is the function of this protein?
May function as an inhibitory translational control element that can negatively regulate protein translation of HR gene.
What are the official names of this protein?
Protein HRURF, HR upstream open reading frame protein.
Protein: YNEA_BACLD
Sequence: MKKESLIFVSLFTAVISCCILFVSFAGKIEERKQYVKIEVQEGDTLWELADRIKGGKTADKHKFIEWVADKNNLPTSVIKPGDVLILPVAKQHSDQYQLAVVE
What is the function of this protein?
Inhibits cell division during the SOS response.  Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery.
What are the official names of this protein?
Cell division suppressor protein YneA.
What is the protein family that this protein belongs to?
Belongs to the YneA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSPO2_XENTR
Sequence: MQFQLFSFVLIILNCVDYSHCQANRWRRSKRASYGTNPICKGCLSCSKDNGCLRCQPKLFFYLRREGMRQYGECLQSCPPGYYGVRGPDMNRCSRCRIENCDSCFSRDFCIKCKSGFYSHKGQCFEECPEGFAPLDDTMVCVDGCEVGPWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPAKDTIPCPTIAESRRCKMAMRHCPGGTRTTKKKDKKNKKKKKKLLERAQEQHSVVLATDRSSQ
What is the function of this protein?
Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors.  Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  Acts both in the canonical.  Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway (By similarity).  Activates neural markers and promotes muscle formation.  Overexpression blocks activin, nodal and BMP4 signaling, suggesting that it may negatively regulate the TGF-beta pathway (By similarity).  During embryonic development, plays a crucial role in limb specification, amplifying the Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3, hence governing the number of limbs an embryo should form (PubMed:29769720).
What are the official names of this protein?
R-spondin-2, Roof plate-specific spondin-2.
What is the protein family that this protein belongs to?
Belongs to the R-spondin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBAT_HORSE
Sequence: MALAAADRATVRALWKKMGSNVGVYATEALERMFLGFPSTTTYFLHLDLSLGSTQVKAHGQKVADALTLAVEHLEDLPRALSALRHRHVRELRVDPASFQLLGHCLLVTPARHFPGDFSPTLHASLVKFLSHVISALASDCR
What are the official names of this protein?
Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATPA1_LISW6
Sequence: MKTIQFDMNKYETHVDLEYLKEHGRVEKISDGVIFCSGLENAALHQAVLIDERHRGVILELNEEFVGIGLIDKTSDILEGMNVSVTDHFIEVNLFDDMAGRIIDTTGKMLYEESEEQPTSSSPLFRVTPEIMTIDSVTRPLNTGLAVIDSITPIGRGQRQLILGNRQSGKTQIAVDTIINQHDQNVHCIYVAIGLKAAYIAEVIETLRNHDALKYSTVVATAASDSLTAQYLTPYAGMAVAEALREQGKDVLIIFDDLTKHADAYRAITLLFNRPPGREAYPGDSFYIHSSLLERAVQMNPEHGGGSITALPMIETLSDDVTAYIPTNVISITDGQLFLKSDLFNRGQKPAVDVGVSVSRIGGDAQHPIIRKLSKNLTLILSQFEELKELLDFGNGLDEGSMKMVTDGRILTELFKQKILSPLSVTDLIVILYAFQNGFLTKVPPAKIESFKGLLLEKAHARNDFIAFSNDIKDISELSDAHTKMLEEIIQEVGRLFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AMYB_HORVU
Sequence: MEVNVKGNYVQVYVMLPLDAVSVNNRFEKGDELRAQLRKLVEAGVDGVMVDVWWGLVEGKGPKAYDWSAYKQLFELVQKAGLKLQAIMSFHQCGGNVGDAVNIPIPQWVRDVGTRDPDIFYTDGHGTRNIEYLTLGVDNQPLFHGRSAVQMYADYMTSFRENMKDFLDAGVIVDIEVGLGPAGEMRYPSYPQSHGWSFPGIGEFICYDKYLQADFKAAAAAVGHPEWEFPNDVGQYNDTPERTQFFRDNGTYLSEKGRFFLAWYSNNLIKHGDRILDEANKVFLGYKVQLAIKISGIHWWYKVPSHAAELTAGYYNLHDRDGYRTIARMLKRHRASINFTCAEMRDLEQSSQAMSAPEELVQQVLSAGWREGLNVACENALPRYDPTAYNTILRNARPHGINQSGPPEHKLFGFTYLRLSNQLVEGQNYVNFKTFVDRMHANLPRDPYVDPMAPLPRSGPEISIEMILQAAQPKLQPFPFQEHTDLPVGPTGGMGGQAEGPTCGMGGQVKGPTGGMGGQAEDPTSGIGGELPATM
What are the official names of this protein?
Beta-amylase, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: RL13_CLOPS
Sequence: MKSYIAKAQEVERKWYVVDAAGKPLGRVASQVASILRGKNKPTFTPNVDCGDFVIVINAEKVVLTGKKLDQKMLRKHSLYAGGLKETPYREVLEKKPEFAFEEAVRRMLPTGVLGRKMLKKLNVYRGAEHNHAAQKPEVLELRY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SL5_ECHPL
Sequence: MGRFIFISFGLLVVFLSLSGTEAECLPDWFHYEGHCYRVFDEPKTWADAEKFCSEQANGGHLVSVHSKKEAGLVGVLAYQTLESPIVWMGLSKIWNQCDWTWTNGAKLKYEAWAEESYCIHITSKKKEWKSLPCRNYGHFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 5, C-type lectin 5, CTL-5.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOB_ECOLU
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: TRPA_PROMT
Sequence: MKSTNISRSFSKIKKEKRIALMPFLMAGDPDLETTAKILLELQANGADMIELGIPYSDPLADGPIIQLAASRALSAGTSPDRVFKMLFELRDQLTIPIILFTYSNPLINKGLEEFCLQASKVGVSGLVVPDLPLEEAEKLSDIAESKEIDLVLLVAPTTPKDRMKRIAATSNGFTYLVSVTGVTGERSSLEDNVGSLVQQLKDSSSSPIAVGFGISDVKHIEQVREWGADGAIVGSALVKRIANASIEMKVEEAGSFCKELRAATNEYFFK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LEPA_ACIET
Sequence: MNHIRNFSIIAHIDHGKSTLADRIIQRCGGLADREMEAQVLDSMDIEKERGITIKAQTAALQYKARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVEVLPVLNKMDLPQADPDTAKAEIEDVIGIDASEAIAISAKTGMGIDDVLEQIVAKVPAPRGKPDAPLRAMIIDSWFDSYVGVVMLVRVVDGRLQKGERFKMMASGAAYEANNLGVFTPAQQSRDALEAGEVGYIIAGIKELKAAKVGDTITLEKKLPNNLGPATEALPGFKEIQPQVFAGLYPTEANQYDALRDALEKLQLNDASLHFEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVVYEVVKGDGEVIMVENPSKMPDQGKIQEIREPIVTVHLYMPQDYVGPVMTLANQKRGVQMNMQYHGRQVMLTYELPLGEIVLDFFDKLKSVSRGYASMDYEFKEYRPSDVVKVDILLNGEKVDALSIIVHRSQSQYRGRAVAAKMREIISRQMFDVAIQAAIGANIIARETIKALRKNVLAKCYGGDITRKRKLLEKQKAGKKRMKQIGSVEVPQEAFLAILQVED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NSR1_YEAST
Sequence: MAKTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSSSSDSESEAETKKEESKDSSSSSSDSSSDEEEEEEKEETKKEESKESSSSDSSSSSSSDSESEKEESNDKKRKSEDAEEEEDEESSNKKQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPNNDGGRGGSRGFGGRGGGRGGNRGFGGRGGARGGRGGFRPSGSGANTAPLGRSRNTASFAGSKKTFD
What is the function of this protein?
Involved in pre-rRNA processing (PubMed:1644811).  Specifically binds nuclear localization sequences (PubMed:1706724).  Candidate for a receptor at the nucleus that may be involved in both RNA and protein transport (Probable).  Binds telomeric sequences of the type (TG[1-3])n in vitro (PubMed:7800479).
What are the official names of this protein?
Nuclear localization sequence-binding protein, p67.
What is the protein family that this protein belongs to?
Belongs to the RRM GAR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: IGHDM_MOUSE
Sequence: DKKEPDMFLLSECKAPEENEKINLGCLVIGSQPLKISWEPKKSSIVEHVFPSEMRNGNYTMVLQVTVLASELNLNHTCTINKPKRKEKPFKFPESWDSQSSKRVTPTLQAKNHSTEATKAITTKKDIEGAMAPSNLTVNILTTSTHPEMSSWLLCEVSGFFPENIHLMWLGVHSKMKSTNFVTANPTAQPGGTFQTWSVLRLPVALSSSLDTYTCVVEHEASKTKLNASKSLAISGIVNTIQHSCIMDEQSDSYMDLEEENGLWPTMCTFVALFLLTLLYSGFVTFIKVK
What are the official names of this protein?
Ig delta chain C region membrane-bound form.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SCAI_DICDI
Sequence: MEITTKSSTTTDDLNNNNNKTVTPIKSENSATGHTSPPNNSTTTTTSSTSAQPITVLPTEIIKTFEHLLRKSQRLFIGLRDLPQFGRQWQPFFQKTFELYTKLWKFQQQYRSILEDKSKYGLKRCEIGEIASKIGQLYYHYYLRTSDTNYLNESYIFYEAIRLRSYFKDVSLDKTPDMMVKQLRYYARFIVVCLLLNKKKVVFDLIEELLKHVNDYTKIYKPSDAQEWSLVLQEIFSFLQADQCATFSDTNQSPSLTNSGNIINNNSNSNNNNGEHTNNTVQSHRLNHLNCPSPPFPLESTQILQQAILVGSQQNQIKFSEITLDMFRMTQSLEYEPMSEAKENDMKLKQQLTALQQQQQQQAAEAKEKNNGTDQQNTTIPSQPLQQHLHHQQQQQQNGNGSGIKKRNPHKYLLYRPTISQILLFLSYSFKELGDNKAMLLYICADGFTNEDNHVNQHIQPPPSIQQETVPSLIDDSNTNIPITTTATATNPLYNKLFTKGLTLNMQKPSQAINSPTVNNNNNNTTTNVTVPTTTTTATNVTAQTTTTTTTTNSTSTSTTSNIPIYKYNEAPFNTKVESLYPMDLLPFCRKPFFLIVNSQSSDIFNELPTFNQPFVSLLSPQSIPKKLVSNLKCGNLFTFFLHDPISAFCDISCGNKIPSKTFNNISLLAQNSLEIISKLLFECVDLHPSFSFFLLDDFLRSFIIRFIFCHATFYLHKEFQDNIYQVKSNPPLPKSLLYNQSILKSIHQLVSELDVSDQFLGLNENRLVIHEN
What is the function of this protein?
May function as a transcriptional cofactor with a repressor activity.
What are the official names of this protein?
Protein SCAI homolog.
What is the protein family that this protein belongs to?
Belongs to the SCAI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: VE4_HPV6C
Sequence: MVVPIIGKYVMAAQLYVLLHLYLALYEKYPLLNLLHTPPHRPPPLQCPPAPRKTACRRRLESEHVDRPLTTPCVWPTLDPWTVQSTTSSLTITTSTKEGTTVTVQLRL
What are the official names of this protein?
Probable protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
Protein: RPOA_PSYA2
Sequence: MMLNATEFLTPNAINVDTVNETIAKVTLEPLERGFGHTLGNALRRILLSSLPGAAVIEAEIDGVDHEYSTLEGLQEDVLDLLLNLKGLAITLHDQNEVFLTLDKQGPGTITAADITLPHNVDIINPELVLGTLSDRGHLKMRLRVVMGRGYEPANQRREDGDTKAIGRLKLDASFSPVLRVAYQVENARVEQRTDLDRLIIELETNGTIDPEEAIRKAATILQQQISIFVDLEAEEAPEPVKEKEEVDPVLLRPVDDLELTVRSANCLKAENIYYIGDLVQRSETELLKTPNLGKKSLTEIKDVLASKDLELGMRLDNWPPADLRVDDRFSYRSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MNMA_MYCSJ
Sequence: MRVLVAMSGGVDSSVAAARMVDAGHDVVGVHLALSATPGTLRTGSRGCCSKEDAGDARRVADVLDIPFYVWDFADRFKEDVIDDFVASYERGETPNPCVRCNEKIKFSALAGRALALGFDALATGHYARLSDGRLRRAVDADKDQSYVLAVLTAQQLRHAVFPIGDTPKAQIRAEAAERGLAVADKPDSHDICFIPSGDTRAFLGARIGVRRGAVVDAGGTKLAEHEGVHGFTIGQRKGLGIAGPGPDGQPRYVTGIDAATGTVRVGGAEDLDVSRLTGERPVFTSGAAFGGPVECQVQVRAHGGLADAVASHDAGVLSVELRAPLRGVAAGQTMVIYRPDPEGDEVLASATISGAAGR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_CHLTR
Sequence: MGFSSLLTTCRYLLYSGAGNSFILGESMPSLEDVLFLCQEEMVDGFLCVESSEIADAKLTVFNSDGSIASMCGNGLRCAMAHVAQCFGLEDVSIETERGVYQGKFFSMNRVLVDMTLPDWKKAERKLTHVLPGMPEQVFFIDTGVPHVVVFVSDLSKVPVQEWGSFLRYHEDFAPEGVNVDFVQRKKDDLLLVYTYERGCERETLSCGTGMLASALVAADIFSLGQDFSIAVCSRSRNLIKIFSEKGKVFLEGPVSLLNRSENFGWLEPKSRRFG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_GEOUR
Sequence: MADLETYFKELVDGRRKAVADRLLLAFLTPFSLVYALLMRLRRATYASGLFPVRRLGKPVISVGNIVAGGTGKTPTVATLARLLMARGKRVAVLSRGYGGSLAGEIRIVSDGKTLQATAEEAGDEPYLLAASIPRLMVVVGADRYRAGRLAEDRLNPDIFILDDGFQHLRLHRDLNILLLDSRSPFGNGRTFPAGLLREPKSALQRADIVIFTRCVEGDPPKAGVAIDKPICRASHVLTGVVPLPGGQAQPFAHLAGKKGLAFAGIADPAAFFDAMEKEGLSIIATLAFADHAGYGEDEIAAICRLKEASRASYIVTTEKDAVKLASYLDRLGPIYAAVLEVRFLDEGVVVAQLEKLLYK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: BIOB_THET2
Sequence: MAWPDLDPPRLAERPLSLQEALFVLEAPPEALPALAEAAIRVKEYFFGRRLKLVRLLNVKSGFCPEDCAYCAQSARSQAAIARYPLLSLEEILERAEEAQRLSARRFCLVAALRGPTPKVLERLGEAAQAIKARFPLELCASLGLLEEGMAEALKAAGFDYYNHNLNTAPSLYPRIATTHTYQDRLWTLKRAREAGLKLCSGVILGMGEGPKEVYEMALALRELGVESLPVNFLLPIPGTPLGDGRTVAGLTPERALKALILFRLLNPKAELRASAGRERYLGPYEPLAFRMVNSIFLQGYLTQPGSPWERDRALWESLGLDVEEGACG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SYK_PSEE4
Sequence: MSDLKTEAQDLQQEENALIALRKEKLAAERVKGNAFPNDFRRDSYCNDLQKQYADKTKEELEAAAIPVKVAGRIMLNRGSFMVIQDMTGRIQVYVNRKTLSEDTLAAVKTWDLGDIISAEGTLARSGKGDLYVEMTNVRLLTKSLRPLPDKHHGLTDTEQRYRQRYVDLMVNEETRHTFRVRSQVISHIRKFLIERDFLEVETPMLQTIPGGAAAKPFETHHNALDMAMFLRIAPELYLKRLVVGGFEKVFEINRNFRNEGVSTRHNPEFTMLEFYQAYADYRDNMDLTEELFRELAQLVLGSTDVPYGDKVFHFGEPFVRLSVFDSILKYNPELTAADLQDVDRAREIAKKAGAKVLGHEGLGKLQVMIFEELVEHKLEQPHFITEYPFEVSPLARRNDDNPAVTDRFELFIGGREIANAYSELNDAEDQAERFLAQVAEKDAGDDEAMHYDADFVRALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFPHMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED31_SCHPO
Sequence: METKWLLSKVPDDKSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKNPQFRNDISRADLSKQVNDEIYYEWLGKGLQQYGSADDATLSQPQQEEDEKKVDVKKENE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Cell separation protein sep10, Mediator complex subunit 31, Soh1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATRX_ORSVW
Sequence: METYVNKLHEGSTYTAAVQYNVLEKDDDPASLTIWVPMFQSSISADLLIKELINVNILVRQISTLKGPSLKIMINSRSAVLAQMPNKFTISANVSLDERSKLAYDITTPCEIKACSLTCLKVKNMLTTVKDLTMKTFNPTHEIIALCEFENIMTSKKVVIPTFLRSINVKAKDLDSLENIATTEFKNAITNAKIIPYAGLVLVITVTDNKGAFKYIKPQSQFIVDLGAYLEKESIYYVTTNWKHTATRFSIKPIED
What is the function of this protein?
Plays a crucial role in virus assembly into filaments and budding.  Early in infection, localizes in the nucleus where it may inhibit host cell transcription.  Later in infection, traffics to the cytoplasm to associate with inclusion bodies, the site of viral transcription and replication.  During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the pneumovirinae M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the cytoplasm, associates with inclusion bodies. During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: EIF3K_CULQU
Sequence: MDHYVKMEDGKVMPIQEMLKSIERYNPEHLKVIEAYVEDQAKDNKYDLEANLACLKLYQFNPQMMNLDVTYTILLKSLTNFPHTDFVLCKCLLLPAQMNDDSVKEIVYLADILEKCDFTLFWSRVQKNPQFFKKITGFSESIRKFVCHVVGITFQSIEKQYLVRLLGDVDDKVLNAWVKKNGWKEEGEYILVAQQEGNIKTKHITEKIDFENLGPLMANCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR_BUCBP
Sequence: MNISIIVAMSQNLVIGQKNSIPWNIPKDLSWFKKHTIKKSIIMGRKTWESIGRVLPMRQNIVLTRQKNIKNTNVLFVNSISKAIQSALYKNEIMIIGGSNLYNQMLTSANKLYITHIEKYILGDTYFPTYDHLPWKIIFKKKIIEHEKTKNSFYVTFKILKKIT
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: PMPD_CHLMU
Sequence: MSSEKDKKNSCSKFSLSVVAAILASMSGLSNCSDLYAVGSSADHPAYLIPQAGLLLDHIKDIFIGPKDSQDKGQYKLIIGEAGSFQDSNAETLPQKVEHSTLFSVTTPIIVQGIDQQDQVSSQGLVCNFSGDHSEEIFERESFLGIAFLGNGSKDGITLTDIKSSLSGAALYSSDDLIFERIKGDIELSSCSSLERGGACSAQSILIHDCQGLTVKHCAAGVNVEGVSASDHLGFGGGAFSTTSSLSGEKSLYMPAGDIVVATCDGPVCFEGNSAQLANGGAIAASGKVLFVANEKKISFTDNQALSGGAISASSSISFQNCAELVFKSNLAKGVKDKCSLGGGALASLESVVLKDNLGITYEKNQSYSEGGAIFGKDCEIFENRGPVVFRDNTAALGGGAILAQQTVAICGNKSGISFEGSKSSFGGAIACGNFSSENNSSALGSIDISNNLGDISFLRTLCTTSDLGQTDYQGGGALFAENISLSENAGAITFKDNIVKTFASNGKMLGGGAILASGNVLISKNSGEISFVGNARAPQAIPTRSSDELSFGAQLTQTTSGCSGGGALFGKEVAIVQNATVVFEQNRLQCGEQETHGGGGAVYGMESASIIGNSFVRFGNNYAVGNQISGGALLSKKVRLAENTRVDFSRNIATFCGGAVQVSDGSCELINNGYVLFRDNRGQTFGGAISCLKGDVIISGNKDRVEFRDNIVTRPYFEENEEKVETADINSDKQEAEERSLLENIEQSFITATNQTFFLEEEKLPSEAFISAEELSKRRECAGGAIFAKRVYITDNKEPILFSHNFSDVYGGAIFTGSLQETDKQDVVTPEVVISGNDGDVIFSGNAAKHDKHLPDTGGGAICTQNLTISQNNGNVLFLNNFACSGGAVRIEDHGEVLLEAFGGDIIFNGNSSFRAQGSDAIYFAGKDSRIKALNATEGHAIVFQDALVFENIEERKSSGLLVINSQENEGYTGSVRFLGSESKVPQWIHVQQGGLELLHGAILCSYGVKQDPRAKIVLSAGSKLKILDSEQENNAEIGDLEDSVNSEKTPSLWIGKNAQAKVPLVDIHTISIDLASFSSKAQETPEEAPQVIVPKGSCVHSGELSLELVNTTGKGYENHALLKNDTQVSLMSFKEENDGSLEDLSKLSVSDLRIKVSTPDIVEETYGHMGDWSEATIQDGALVINWHPTGYKLDPQKAGSLVFNALWEEEAVLSTLKNARIAHNLTIQRMEFDYSTNAWGLAFSSFRELSSEKLVSVDGYRGSYIGASAGIDTQLMEDFVLGISTASFFGKMHSQNFDAEISRHGFVGSVYTGFLAGAWFFKGQYSLGETHNDMTTRYGVLGESNATWKSRGVLADALVEYRSLVGPARPKFYALHFNPYVEVSYASAKFPSFVEQGGEARAFEETSLTNITVPFGMKFELSFTKGQFSETNSLGIGCAWEMYRKVEGRSVELLEAGFDWEGSPIDLPKQELRVALENNTEWSSYFSTALGVTAFCGGFSSMDNKLGYEANAGMRLIF
What are the official names of this protein?
Probable outer membrane protein PmpD, Polymorphic membrane protein D.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.