PharMolix/UniProtQA huggingface dataset:
Protein: VATB_THEPX
Sequence: MLREYKTVREIVGPLMLVEKVEGVKYNELVEIETGSGEIRRGQVLEVNGDKALVQLFEGSTGLNINDCKVRFVGKSIELGVSIDMLGRVFDGLGRPRDKGPMIIPEKRLDINGNPINPTARDYPSEFIQTGISAIDGLNTLVRGQKLPIFSGSGLPHAQLAAQIARQAKVLGTDSKFAVVFAAMGITFEEADYFISDFRRTGAIDRTVLFINLANDPAIERIATPRMALTCAEFLAYEKEMHVLVIMTDMTNYCEALREVSAARKEVPGRRGYPGYLYTDLATIYERAGRIKGRKGSITQIPILTMPEDDKTHPIPDLTGYITEGQIILSRDLYRKGIYPPIDVLPSLSRLKDKGIGQGKTREDHADLMNQLFASYARGKQAKELAVILGEAALSDTDKLYAKFADEFEARYVAQREDEDRSIEETLAIGWDLLTILPRAELKRVRDEYIDKYLPEKGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: FB300_ARATH
Sequence: MRTLRRNVTENRLTISRRRTEKKTSPNKTEKSVQIPVDIIIEILLRLPAKSIATCRCVSKLWISVICRQDFTELFLTRSLHRPQLLFCCKKDGNLFFFSSPQLQNPYENSSAISLKNFSLCYKISRPVNGLICFKRKEMNETVTVICNPSTGHTLSLPKPMKTSIGPSRFFVYEPIQKQFKVLLSYKSDEHQVLTLGTGELSWRIIECSMPHILGMSEICINGVLYYPAINLSSGDYIIVCFDVRSEKFRFITVMEEFIKAAHDGTLINYNGKLASLVSERYCFVDGRSKSIELWVLQDAEKKEWSKHTYVLPAWWQHRIGTLNLRFVGVTRTNEIMLSPCYQTVPFDVYYFNIERKTMMSVAIQGMEAFQGHLVFTYLDHVENVKLLHNMF
What are the official names of this protein?
F-box protein At5g65850.
Protein: TPPP_MOUSE
Sequence: MADSKAKPAKAANKTPPKSPGDPARAAKRLSLESEGANEGATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK
What is the function of this protein?
Regulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath (PubMed:31522887).  Acts as a microtubule nucleation factor in oligodendrocytes: specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, and promotes microtubule nucleation, an important step for elongation of the myelin sheath (PubMed:31522887).  Required for both uniform polarized growth of distal microtubules as well as directing the branching of proximal processes (PubMed:31522887).  Shows magnesium-dependent GTPase activity; the role of the GTPase activity is unclear (By similarity).  In addition to microtubule nucleation activity, also involved in microtubule bundling and stabilization of existing microtubules, thereby maintaining the integrity of the microtubule network (PubMed:18028908).  Regulates microtubule dynamics by promoting tubulin acetylation: acts by inhibiting the tubulin deacetylase activity of HDAC6 (By similarity).  Also regulates cell migration: phosphorylation by ROCK1 inhibits interaction with HDAC6, resulting in decreased acetylation of tubulin and increased cell motility (By similarity).  Plays a role in cell proliferation by regulating the G1/S-phase transition (By similarity).  Involved in astral microtubule organization and mitotic spindle orientation during early stage of mitosis; this process is regulated by phosphorylation by LIMK2 (By similarity).
What are the official names of this protein?
Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p25-alpha.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
What are the subcellular locations of this protein?
Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies. During mitosis, colocalizes with LIMK2 at the mitotic spindle (By similarity).
Protein: UPPP_ENT38
Sequence: MSDMHSLLVAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGETAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPPQHEGEGKGRLTLIHILLGMVPAVVLGLIFHDAIKSLFNPINVMYALVVGGVLLIAAELLKPKEPKAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSYHFLTAADFPMFAVGFVTAFLVALVAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURA_CERS1
Sequence: MDSILVKGNGELRGQIPIAGAKNACLALMPATLLSDEPLTLTNAPRLSDIRTMTQLLQSLGAEVASLQGGQVLALSSHALTDHRADYDIVRKMRASILVLGPMLARDGHAVVSLPGGCAIGARPVDLHLKALEAMGAELDLRDGYIHAKAPAGGLKGARVVFPLVSVGATENALMAATLAKGTTVLENAAREPEIVDLARCLRRMGAQIEGEGSSTITIEGVDRLGGATHPVVTDRIELGTYMLAPAICGGEVELLGGRIELVGAFCEKLDAAGISVEETERGLRVARRNGRVKAVDVMTEPFPGFPTDLQAQMMALLCTAEGTSVLEERIFENRFMHAPELIRMGARIEVHGGTATVTGVEKLRGAPVMATDLRASVSLILAGLAAEGETIVSRVYHLDRGYERVEEKLSACGAQIRRIPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CI027_HUMAN
Sequence: MLCVSGFTSNLYSSKKDDKMKEISRTSNWGSSFSEKSGCMQTHPSMNLDCRDVTYVMNLLLIAHHHLLQ
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00474, Protein EST-YD1.
Protein: SWT2A_ORYSI
Sequence: MMNALGLSVAATSTGSPFHDVCCYGAGIAGNIFALVLFISPLPTFKRIVRNGSTEQFSAMPYIYSLLNCLICLWYGLPFVSYGVVLVATVNSIGALFQLAYTATFIAFADAKNRVKVSSLLVMVFGVFALIVYVSLALFDHQTRQLFVGYLSVASLIFMFASPLSIINLVIRTKSVEYMPFYLSLSMFLMSVSFFAYGVLLHDFFIYIPNGIGTVLGVIQLVLYGYFRKGSREDSLPLLVTHT
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET2a, OsSWEET2a.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNP4_METLZ
Sequence: MAKAEKGVSAKKIAQERVDILFERAKEARDEPELSARYVSLAREMAMKQRVRLAHYHRRSFCPSCHAYFIPGTNLRVRIQHGKIIYTCGICGAVTRIPLNKKTESR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYPM_MOUSE
Sequence: MEGLLTRCRTLSALAACSLRHCRYIIHKCYHRAPGRGQRLVLSRMFQPQNLREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRAVEKLVRVIDQEMQAIGGQKINMPSLSPAELWRATSRWDLMGRELLRLRDRHGKEYCLGPTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSSEAAQETYGLVCDAYCRLFDRLGLQWMKARADVGSIGGTMSHEFQLPVDIGEDRLVVCPSCHFSANTEILDLSQKICPDCQGPLTETKGIEVGHTFYLSTKYSSIFNALFTNAHGESLLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPRLLAPYQVCVIPPKKGSKETAATEIVEKLYDDIMEAVPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIAGKRALEDPAHFEVWSQNTGEVVFLTKEGVMELLTGVHVV
What are the official names of this protein?
Probable proline--tRNA ligase, mitochondrial, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TX13A_HUMAN
Sequence: MALRPEDPSSGFRHSNVVAFINEKMARHTKGPEFYLENISLSWEKVEDKLRAILEDSEVPSEVKEACTWGSLALGVRFAHRQAQLQRHRVRWLHGFAKLHKSAAQALASDLKKLREQQETERKEAASRLRMAQTSLVEVQKERDKELVSPHEWEQGAGWPGLATAGGVCTEGAAEEEEEAAVAAAGAAGGKGAEEEQRDVEVVAAPVEAMAPPVEAGAAPMETQFPHVEARAASMETTEKLERILLQLLGDADQEKYTYWGQKEGDLRSVETATSYFSGTTNPWSRASSEPLPVQLPASYSYSYSSPFSSFSDIPTISPPQATVTAPVPPQLPSDWEAFDTSLWSDGGPHRIDHQEHPRDRRYSEPHQQRPPVYRRPGDWDCPWCNAVNFSRRDTCFDCGKGIWLQKPH
What are the official names of this protein?
Testis-expressed protein 13A.
What is the protein family that this protein belongs to?
Belongs to the TEX13 family.
Protein: AMY1_LIPKO
Sequence: MLLINFFIAVLGVISLSPIVVARYILRRDCTTVTVLSSPESVTGSNHVQLASYEMCGSTLSASLYVYNDDYDKIVTLYYLTSSGTTGSTLALILPVWSNNWELWTLSAIAAGAVEITGASYVDSDTSVTYTTSLDLPLTTTSASVPTGTAANWRGRSIYQVVTDRFARTDGSITYSCDVTDRVYCGGSYRGIINMLDYIQGMGFTAIWISPIVENIPDDTGYGYAYHGYWMKDIFALNTNFGGADDLIALATELHNRGMYLMVDIVVNHFAFSGNHADVDYSEYFPYSSQDYFHSFCWITDYSNQTNVEECWLGDDSVPLVDVNTQLDTVKSEYQSWVKQLIANYSIDGLRIDTVKHVQMDFWAPFQEAAGIYTVGEVFDGDPSYTCPYQENLDGVLNYPVYYPVVSAFQRVGGSISSLVDMIDTLKSECIDTTLLGSFLENQDNPRFPSYTSDESLIKNAIAFTILSDGIPIIYYGQEQGLNGGNDPYNREALWPTGYSTTSTFYEYIASLNQIRNHAIYIDDTYLTYQNWVIYSDSTTIAMRKGFTGNQIITVLSNLGSSGSSYTLTLSNTGYTASSVVYEILTCTAVTVDLSGNLAVPMSGGLPRVFYPESQLVGSGICSM
What are the official names of this protein?
Alpha-amylase 1, 1,4-alpha-D-glucan glucanohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RS4_GLOVI
Sequence: MARYTGPVCKLCRAVGMKLYLKGIRCSSPKCAIERRNFRPGVHGQARQKLSEYAIRLKEKQKARWSYGVLEKQFRRTFSDASRATGNTGAKFLELLERRLDNVVYRLGFATSRAQARQWVNHGHFAVNGRRVSIPSYRVRPGDAITVMPNSAAFVKEALEAASLPQAPKWLEANRETLAATVKALPEREDIDTPVQELLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TRPA_YERPE
Sequence: MERYQQLFKQLAAKKEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGIPFSDPLADGPTIQNAALRAFAAGVTPGICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADVPFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQLPLNHLVDKLREYNAAPALQGFGISEPAQVKASLAAGAAGAISGSAIVKIIEKNVAQPVEMLVQLTRFVTEMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RS3_FRAT1
Sequence: MGQKVNPNGIRLGYIRDWRSTWYADSSRYATKLNEDIKVREFLHKKLAAAAVSKIQIERPAQNAKITIHTARSGIVIGKKGEDVEKLRAEVHKLMGIPVQINIEEVRKPEIDAKLVAESVAQQLEKRVMFRRAMKKAMQAAMKSGAKGIKIMVSGRLGGAEIARSEWARDGRVPLQTFRADVDYATAEALTTYGVIGVKVWIYKGEILPGQIAEKKNNKKRS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CCD21_ARATH
Sequence: MAENLACGETSESWIIDNDDDDINYGGGFTNEIDYNHQLFAKDDNFGGNGSIPMMGSSSSSLSEDRIKEMLVREIEFCPGTDYVKRLLSGDLDLSVRNQALDWILKVCAHYHFGHLCICLSMNYLDRFLTSYELPKDKDWAAQLLAVSCLSLASKMEETDVPHIVDLQVEDPKFVFEAKTIKRMELLVVTTLNWRLQALTPFSFIDYFVDKISGHVSENLIYRSSRFILNTTKAIEFLDFRPSEIAAAAAVSVSISGETECIDEEKALSSLIYVKQERVKRCLNLMRSLTGEENVRGTSLSQEQARVAVRAVPASPVGVLEATCLSYRSEERTVESCTNSSQSSPDNNNNNNNSNKRRRKQ
What is the function of this protein?
Acts on the G1 phase of the cell cycle to control cell division rate in both shoot and root meristems.  The complex formed with CDKA-1 phosphorylates plant retinoblastoma protein.
What are the official names of this protein?
Cyclin-D2-1, Cyclin-delta-2, Cyclin-d2, G1/S-specific cyclin-D2-1, CycD2;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: EX7L_BRUC2
Sequence: MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAASHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERQTAFTHRANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVSPGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIMA1_PIG
Sequence: MESTPFNRQQWTSLSLRVTAKELSLVNKNKSSAIVEIFSKYQKAAEEANMEKRRSNTENLPQHFRRGNLTVLKKKWENPAPGVESLPESTRNSSAEVRHRGDPPPAEVASSSASGVEADQGVCPRPRFSSPPEVPYPNPRIKDTEHLKDHSAESKKMENCLAESRHEVGKPETSENAEASNKIEKYNVPLNRLKMMFERGEPAQTKILRAQSRSTGGRKISENSYSLDDLEIGPGQLSSSAFNTEKSESRRNLEFPRLSDTSIKDRMAKYQAAVSKQSSSTNYTNELKANGGEIKTHKLEQKENVPPGPEVCISHQDGEKVSASENSLAACSTPPEDDSCKSQVKSDVQQPVHPKPLSPVARASSLSESSPPKAVKKFQAPARETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHRPHKDLWASKLENEETLERPAQLPNAAEIPQSPGVEDAPIAKVGVLTASMEAKASSQLEKEDKPAETKKLRIAWPPPTELSSSGSALEEGIKVSKPKWPPEDEVSKPEAPEDVDLDLKKLRRSSSLKERSRPFTVAASFRTASVKSPKPLSPPMRKGWSLSEQSEEFGGGVAAERKQMEKASASEKNGSVGKTTWPSKESRGGEAAGRSKEVQDFEIGSENLIENGASLDEGDRDLLQQQSPLEPKSKNWSSFADNTSAKEFTTQKQKSQDVEFWEGEVVEELSVEEQIKRNRYYDEEEDEE
What is the function of this protein?
Actin-binding protein involved in actin cytoskeleton regulation and dynamics.  Increases the number and size of actin stress fibers and inhibits membrane ruffling.  Inhibits actin filament depolymerization.  Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments (By similarity).  Plays a role in cholesterol homeostasis.  Influences plasma cholesterol levels through regulation of intestinal cholesterol absorption.  May act as a scaffold protein by regulating NPC1L1 transportation, an essential protein for cholesterol absorption, to the plasma membrane by recruiting MYO5B to NPC1L1, and thus facilitates cholesterol uptake (By similarity).
What are the official names of this protein?
LIM domain and actin-binding protein 1, Epithelial protein lost in neoplasm.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cell membrane. Note=This cytoskeletal protein colocalizes with actin stress fibers and focal adhesion plaques. Expressed mainly in the brush border membrane of the small intestine and colocalizes with NPC1L1 and MYO5B (By similarity). Colocalizes with PXN at focal adhesions in mesangial cells (By similarity). Colocalizes with actin stress fibers in quiescent cells. PDGF stimulation induced disassembly of stress fibers and formation of peripheral and dorsal ruffles, where LIMA1 is relocalized (By similarity).
Protein: SECY_MYCTO
Sequence: MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVGNSWWDKFVGTYLSDPSNLVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAGGTVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GBLP_YEAST
Sequence: MASNEVLVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAATATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQVMTAN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  Located at the head of the 40S ribosomal subunit in the vicinity of the mRNA exit channel, RACK1 serves as a scaffold protein that can recruit other proteins to the ribosome.  Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation (PubMed:28223409).  Involved in the negative regulation of translation of a specific subset of proteins (PubMed:15340087).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein, Receptor for activated C kinase, Receptor of activated protein kinase C 1, RACK1, Small ribosomal subunit protein RACK1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_RICB8
Sequence: MINISFPDGSVKQFEKNITAFEIAVVISTSLAKAAMIAEINGDLKDLSTQIDNDCRLRILTAKDPECLEVIRHDAAHLTAEAVKELFPETQVTIGPAIENGYYYDFARDKPFTTDDLAVIEAKMHELAKKNEKVTRELWDREKAVEFFKSIGEHYKAEIIASIPSNEPISLYRQGNFIDLCRGPHAPSTGFVKHFKLMKVAGAYWRGDSRNEVLQRIYGTAWATKEQLESYLFMLEEAEKRDHRKLGKELDLFHFQEEAQGMVFWHDKGWSVYNTIEQYIRRKIRKNGYIEVKTPVLVDKSLWELSGHWEKFRDDMFALETDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMSEFGLCHRNEASGALHGLMRVRSLVQDDAHIFCAEEQITDETVSFCKLLTEVYKDFGFTDIKVKFSDRPEVRAGSSETWDKAENALKEAVEKAGYSYTLNPGEGAFYGPKLEFVLTDAIGRQWQCGTLQMDFVLPERLDASYVAASGEKKRPVMLHRAILGSLERFIGILIEEYAGRFPLWLAPVQVAIATITSDLNDYALEVQKALIESGVRVDINISPDKINYKIREFSNQKVPMIAVIGKQEKENKQVTIRRLGTTEQEVLSIEQLIEYIREENSK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_SULIK
Sequence: MTDVLVVLKVFPDSDEVNLDNLYTDISNKLPKEYRIIRKETEPIAFGLNALILYVQMPEQTEGGTDNLEEVVNNIQGVSHAEVVGITRLGF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: ATE1_YEAST
Sequence: MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRYMNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRTAPQELNMTKELKKCISRFATRITSEDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPALYSEEKYHLFVKYQEKVHQDYNNSPKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRMKPGEKLKHMGPVHECYYYEGKLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALRDLAIIQRTNLQYYYLGYYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKLFVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESALELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLEGRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM
What is the function of this protein?
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein.  This arginylation is required for degradation of the protein via the ubiquitin pathway (PubMed:2185248).  Does not arginylate cysteine residues (By similarity).
What are the official names of this protein?
Arginyl-tRNA--protein transferase 1, Arginyltransferase 1, R-transferase 1, Arginine-tRNA--protein transferase 1.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_BACMK
Sequence: MQAKAVVRTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINNLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PEBB_GLOVI
Sequence: MTLYEPFLERAQQVLTRRLELAPYPIPVGFERKEALVRGEAVVTTSTAWQSPKLRQIRAAHVQGGGALQVLNFVISPRLEYDLPFFGADLVTLPGGHLIALDMQPLFRDDPAYQAKYTEPIVPLFEAHRAHLEWGGDFPEEARPFFSPAFLWTRPKETGTVETRVFAAFVDYLNAYLDFVERAEPVTHPEGLAAVERAQLRYLHYRAEKDPARGMFRRFYGPEWTEEYIHGFLFDLERRREAVHR
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: YOBA_BACSU
Sequence: MPKIGVSLIVLIMLIIFLAGCNKNEQNGDETKMQSLVGYVVLKDNERAILITDTKAPGKEDYNLSEGQLMNKFKNNIVIVGLSEIDNTDDLKRGEKIKVWFHTRKESNPPSATIQKYELL
What are the official names of this protein?
Uncharacterized protein YobA.
Protein: HRPJ_PSESY
Sequence: MKIVAPPTLPIRPVAPIRAITPAARAIPGSGLPDEKGTSSLQVSRFAAALVQHSRILRERELIASRNALQSRAVKLGELYQLLMSTSDTGLDNAARLLRKKLLQDNDADLEQVLEFADGDAAKAHVVLQAARKQAEDDGAEEEYAALTQTLKHLRRRFGPRARAGINTARAFGRQNIDNKRRTALRNLYGVAVSGQPNVTGLIEALIGEQQEPGEFDLNLRDMRRAIADDLSAITPSASHEQLRTLMHGLTTARHVTTLLRGCEHLLGRMRKKNPKLTVDPPAFLKHMLTLTANGMNVNQTLQLTQHIGGNKLEHQLAFLNGLRADADATADPALAGPEKPPGRAE
What is the function of this protein?
Involved in the secretion of a proteinaceous elicitor of the hypersensitivity response in plants.  Also required for pathogenicity on host plant.
What are the official names of this protein?
Hypersensitivity response secretion protein HrpJ.
What is the protein family that this protein belongs to?
Belongs to the HrpJ/YopN family.