PharMolix/UniProtQA huggingface dataset:
Protein: MTAP2_HUMAN
Sequence: MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEDLLTASKMEFHDQQELTPSTAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGSFTLPLDVMKNEIVTETSPFAPAFLQPDDKKSLQQTSGPATAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEAINQETVQQRDTFTPSGQEPILTEKETELKLEEKTTISDKEAVPKESKPPKPADEEIGIIQTSTEHTFSEQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRVDDKDKIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKSIEPGSDYYELSDTRESVHESIDTMSPMHKNGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSDLPEEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDDYLPATTPALEKAPCFPVESKEEEQIEKVKATGEESTQAEISCESPFLAKDFYKNGTVMAPDLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGLPPVTDENHVIVKTDSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLAAAGRVKDEFSVDKEASAHISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKKTEEAGDEIETFGLGVTYEQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPSKKVEQGLDFAVQGQLDVKISDFGQMASGLNIDDRRATELKLEATQDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAKPDLVHQEAVDKEESYESSGEHESLTMESLKADEGKKETSPESSLIQDEIAVKLSVEIPCPPAVSEADLATDERADVQMEFIQGPKEESKETPDISITPSDVAEPLHETIVSEPAEIQSEEEEIEAQGEYDKLLFRSDTLQITDLGVSGAREEFVETCPSEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEVERRPSPHDEEEFEVEEAAEAQAEPKDGSPEAPASPEREEVALSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
What is the function of this protein?
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization.  They also seem to have a stiffening effect on microtubules.
What are the official names of this protein?
Microtubule-associated protein 2, MAP-2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, dendrite.
Protein: PDGFD_RAT
Sequence: MHRLILVSILVCANFCCYRDTFATPQSASIKALRNANLRRDESNHLTDLYRRDENIRVTGTGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDHQFGLEEAENDICRYDFVEVEDVSESSTVVRGRWCGHKEIPPRITSRTNQIKITFQSDDYFVAKPGFKIYYSFVEDFQPEAASEINWESVTSSFSGVSYHSPSVMDSTLTADALDKAIAEFDTVEDLLKYFNPASWQDDLENLYMDTPRYRGRSYHERKSKVDLDRLNDDVKRYSCTPRNHSVNLREELKLTNAVFFPRCLLVQRCGGNCGCGTLNWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGKAKNMALVDIQLDHHERCDCICSSRPPR
What is the function of this protein?
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.  Potent mitogen for cells of mesenchymal origin.  Plays an important role in wound healing.  Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity).  May play an important role in control of lens epithelial cell proliferation.  Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
What are the official names of this protein?
Platelet-derived growth factor D, PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=Released by platelets upon wounding.
Protein: SNTAN_CHICK
Sequence: MCGCRASVPSTKHYSVNPAPTTRSPPAAAGMPKRIPIAKQLASIKALEKGSDLEKAFATAALVYNNSADPEGKLSKAETKSLLQTQFSRFIQGQENKPKYQEMISALDEEPEKKIDFEDFMISLVSLALLSDLLQEIKNVKSTK
What is the function of this protein?
May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.
What are the official names of this protein?
Sentan, Protein S100-A1-like, S100 calcium-binding protein A1-like.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Expressed exclusively at the cilium tip where it localizes between the cell membrane and peripheral A-subfibers.
Protein: STX2_MOUSE
Sequence: MRDRLPDLTACRTNDDGDTAVVIVEKDHFMDGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLDKEIKKTANRIRGKLKSIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFISDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVAVAVIAVLALIIGLSVGK
What is the function of this protein?
Essential for epithelial morphogenesis.  May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
What are the official names of this protein?
Syntaxin-2, Epimorphin.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: RIHB_ECO5E
Sequence: MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGDTGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDSDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: KDSB_THISH
Sequence: MSFKVAIPARYASTRLPGKPLLMLGGKPMIQHVHERALACGAEEVVIATDDTRISDVAEGFGARVVLTDAHHESGSDRIAEVATELGWRDDDIVVNLQGDEPLTPPDILHQVAEALERHTDAAMATLCTPIETVEQMLDPNVVKVVRDAADYALYFSRAPIPWDRNVGRDVTHRSLEGCHRHIGLYAYRVGFLKAFAAMSPCALELTERLEQLRALHAGARIQCPVASQVPGQGVDVSSDVERVEKLLRA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_THET8
Sequence: MDLPRLYVPATLANLGSGFDALGVALDLYLEVEAHPAPEDAFLYEGEGHVEGTDNLIHEGYRAGMRALGLEPFPLRVRAFNPIPLARGMGSSSAALVAGVALADRLSGGRLGREGVFRVAAGLEGHPDNVAPAVYGGFVAALSDPPLAIPLPRPEGVRFVLAVPPYEVPTPLAREALPREVPLEDAIYNLARSALWPAALSSGRLEALREACRDRLHQPHRAHLMPGVLEAIEGALEAGALAAFVGGAGPTLAALARAGEEAPVIRALSAYRGPEGRTLVLGIGEGYFWKET
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_SALEP
Sequence: MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICSAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: FOLD_BACMK
Sequence: MVAVIIKGNEVAEKKRAQLKEKVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIELPETITEERLLVEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGILELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTRNIKELSKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRAGVVCQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y741_STAEQ
Sequence: MGEVKHLQINYKTDELFADFREFGNKNLYMIEELKGQMIDASSDSPFYGIFVGNKLVARMALLDKGEVEETYFPNSNYYILLWKLEVLDTYQRRGYAKQLLNFAKENKKPIKAIARNNSKAFFLTQGFKDVATKNPEGHDILIWNP
What are the official names of this protein?
Uncharacterized N-acetyltransferase SERP0741.
Protein: HEM3_ECO45
Sequence: MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AMPA_PSEAB
Sequence: MEFLVKSVRPETLKTATLVLAVGEGRKLGASAKAVDDATGGAISAVLKRGDLAGKVGQTLLLQSLPNLKAERVLLVGAGKERELGDRQYRKLASAVLSTLKGLAGADAALALGDLAVKGRGAHAKARLLVETLADGLYVFDRYKSQKAEPLKLKKLTLLADKADSAAVEQGSKEAQAIANGMALTRDLGNLPPNVCHPTFLGEQAKGLAKEFKSLKVEVLDEKKLRELGMGSFLAVAQGSDQPPRLIILQYNGAKKDQAPHVLVGKGITFDTGGISLKPGLGMDEMKFDMCGAASVFGTFRAVLELQLPINLVGLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYAERFKPQSVIDIATLTGACIVALGSNTSGLMGNNEALVRQLLKAGEFADDRAWQLPLFDEYQEQLDSPFADIANIGGPKAGTITAGCFLSRFAKKYHWAHLDIAGTAWISGGKDKGATGRPVPLLTQYLLERAK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABHDB_XENLA
Sequence: MITFKSFHCSRGWHLWKHWRAFHSHSNSGTLFCQNRTTDKNTHATRVVDLSYDLYDGSVLGPPLVLLHGLFGSKSNFQTIARALVRKTGRKVLTLDARNHGCSPHDDIMTYPAMSADVCQILHQLQITNCVLIGHSMGGKTAMTVALQEPKLVERLVSVDISPAPTVPQTGFPHYIAAMQKVHFEEKMPRSTARRLADEQLSSTVKEASIRQFLLTNLVQENGTFKWRVNLEVISRHLQDLLDFPEFQEPYPGPVLFLGGANSPYISSENYPEIERLFPFANVEYIFGAGHWVHADKTHDFLNAICNFVESA
What are the official names of this protein?
Protein ABHD11, Alpha/beta hydrolase domain-containing protein 11, Abhydrolase domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: LPTD_ACTP7
Sequence: MKTRYSVLSVAMTAAFYTQYAQADLREQCLLGVPHFQGEEVTGDQIMMPIEIEADNAVINQPKDATYTGDVAIKQGNRSLFADEVRVEQNGEQERRAFLKGSYRYQDNLIQAHGRDAAMDLGSETAELQNTEFQLVGRQGRGTAESGSFNHNKRILKNATFTACLPNDNAWSIEGNEMIQHIDEEYAEIWHARFKVLGMPVFYSPYLQFPIGDRRRSGLLIPNFHRSSKDGFAYSQPFYWNIAPNMDATITPTYYSRRGWQISPEYRYLTKLGEGIVAGEYIGKDRLDEYRPDDNNRKRYLMHWRHNMSFLTGWRLYVDYTKVSDKRYFSDFDSEYGSSTDGYATQQFKLGYYQPNYNLSISGKKFQTFDELDVGPYRVLPQIDFNYYNDELVKGGDFKLFAQTARFENDSKLMPKAWRFHVEPTLNFPLANRYGSLNFETKLYATHYLQEKGSSKQADDMDKNVTRIIPQVKVDLQTVLEADKQLFKGFNQTFEPRVQYVYRPYKDQSNIGSGLNQSVSFGYDSALLQSDYFSLFNDRRYSGLDRISSANLITAGGTNRFFNEKTGVEVFNFSIGQTYYLSPSKIDDLSQNSTTKRSSSWALESNWKFHRKWNWHGAYQYDTRLNQTSLANTSLQYKPSQDKLVQLSYRFASKDYINQNLRSNTYGQDIKQVGAVVGWELTDRVAFMASHYHDIALKKPVESQLSVNYNTCCWSANVYVARKLTATPIGSPDTINDLYYDNKFGVNFELRFGTNYSSGVRKMLKKGMIPYTEQYGIN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GGTA1_CALJA
Sequence: MNVKGKVILSMLVVSTVIVVFWEYINSPEGSFLWIYHSKNPEVDDSSAQKGWWFPGWFNNGIHNYQQEEEDTDKEKGREEEQRKEDDTTELRLWDWFNPKKRPEVVTVTKWKAPVVWEGTYNKAILENYYAKQKITVGLTVFAIGRYIEHYLEEFVTSANRYFMVGHKVIFYVMVDDVSKVPFIELGPLRSFKVFEVKPEKRWQDISMMRMKTIGEHILAHIQHEVDFLFCMDVDQVFQDHFGVETLGQSVAQLQAWWYKADPDDFTYERRKESAAYIPFGQGDFYYHAAIFGGTPIQVLNITQECFKGILLDKKNDIEAEWHDESHLNEYFLLNKPSKILSPEYCWDYHIGLPSDIKTVKLSWQTKEYNLVRNKV
What is the function of this protein?
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid.  Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3) (By similarity).
What are the official names of this protein?
N-acetyllactosaminide alpha-1,3-galactosyltransferase, UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase, Galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: OR8B3_HUMAN
Sequence: MLARNNSLVTEFILAGLTDHPEFQQPLFFLFLVVYIVTMVGNLGLIILFGLNSHLHTPMYYFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISYVGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHTGCMLRLTFCSANIINHYLCDILPLLQLSCTSTYVNEVVVLIVVGINIMVPSCTILISYVFIVTSILHIKSTQGRSKAFSTCSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVFYTNVVPMLNPLIYSLRNKDVKVALRKALIKIQRRNIF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 8B3, Olfactory receptor OR11-311.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YM02_SCHPO
Sequence: MTALMNHIYIDNPLISNSTNNVTHELLIDLHELYNDGEISRIVLLRTLVTQSADDATWIINLTDDVLNGLPLLKKRDRYTTQCHSTNMASTYDCDTGANAVGARGGATLAADYRGDWGGGVMLYKPLVVKACLTEI
What are the official names of this protein?
Uncharacterized protein C212.02.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPF_CERS4
Sequence: MMDMGASSGLGFMKMHGAGNDFVVIDSRGRGGALVTAGLARALGDRHRGVGFDQLAEIRDQEGADCALDFWNSDGSRSGTCGNATRCVSDYLMRDLGRDEVNLVTARGRLHARRREDGLVAVNMGAPQLLWSEIPLARAMETDSLPLEGTPSAVGMGNPHCIYFVEDAEAVDLAGRGAAVETDPLFPERTNVEFASLIGPDRLRLRVWERGAGITLACGSGACATAVAAARRGLTGRQVRLEMDGGVLEVDWRDEGVWLSGPVARVFEGHLSPEMMALA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_HALSA
Sequence: MLAGGVPHGTVAFAYLAVVFAVTGINHLDGVADAGDAAVVHGDPADRRTVLKDTTTGVGAIAAVVVVVAGLVTGSLGVAALPTWTAVGVVVATEVGAKTSMAAVACLAHAPHDGLGSQFTGNATPGALPAVAGVALPVALASVPSPAAAGALAGAVGAGALTRRWLTGLLGGANGDVFGAVNEVSRVVGLHAGVVVWTL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YR43_CAEEL
Sequence: MVNELSFNCEDAWLNLFVGGEMYPVQVKTLMNPTTCGSYFRDVVKVSDAAIKVRGVQWDTAPNHIKFRVDIDRDGVLFRHVLQYLRNGKLTSLPDDIFTLESLVAEAEFFGLEKYREMLKKKLWKLTGKRQYYACYEDSD
What are the official names of this protein?
Uncharacterized protein F47D12.3.
Protein: CCNG1_PIG
Sequence: MIEVPTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSLEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQESLPYERRNSLNFERLEAQLKACYCRIIFSKAKPSVLALSIIALEIQALKCVELAEGAECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
What is the function of this protein?
May play a role in growth regulation.  Is associated with G2/M phase arrest in response to DNA damage.  May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
What are the official names of this protein?
Cyclin-G1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin G subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KCY_RHOPS
Sequence: MIIAIDGPAASGKGTLGKRLAAHYGFRHLDTGVIYRAVAKALLDGGADLTDEARAVAAARKLDPGIFGDPALKSQTVGDAASVISAYAPLREALVSFQRQFAADPPGAVLDGRDIGTVICPDADVKIFVIADPVVRARRRTLEALARGEAADEARVLADILKRDERDRNRSAAPLTQAPDAVLLDNSNLDIEGGVRAAIDIVEAVRAGRRRV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_WOLPP
Sequence: MSITSQKKKSLISTYAIKEDDTGSSFVQCAILTERISNLTEHFKAHKHDHNSKRGLLILIGRRRKHLNYIKRKFGNEAYQELIEKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RPOB_BORBZ
Sequence: MIKRVHLGQGRADEILDLPNLIEIQLNSYEKFLQLDKLKSKKPLLNEGLESVFRNIFPIKSGNGDVALEYERYYIENDALNFTEKECKRKGQSYEAVLKVRLNLQFLTTGEIRQKDVYMGTIPLMTERGTFIINGAERVVVSQIHRSPGVVFYKEKDLYSARIIPYRGSWLEFEIDSKKDYLYVKIDRKKRILITLFLRALGFDTREKIIETFYNIKKIKVEDGTKRDLPGQYLAKSINIRENMYYRAGDKITLQDVEDFLQNGVNEIELVDFDGYDDISGKRFVSSNVILNCLEKEDAFFALKDGSKELPKESVMLAVYSSLFPGEPISIDNAENDLKTIFFSERRYDLGRVGRYKLSKKFGFDDLTTSVLTMDDIVNTISHLLRIYEGHDILDDIDHLGNRRVRSVGELLTNIYKGAMSRVEKIAKDRMSNKEVFNLKPQELISVKPIVSAVKEFFATSQLSQFMDQVNPLAELTHKRRLNALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSLATYSRVNDYGFLETPYRKVVNGEVTDQLEYLSAIDEEKKCIAQANAAFNSNGKYLEDLVSVRISGDYTTTSPTNIDYMDVSPRQLISVSSALIPFLEHNDANRALMGSNMQRQAVPLLFPKPPIVGTGMESVVAKDSGVVVKAKRSGEVILATSSKIVVKPFEAENAKDLDEYHIVKYERTNQDTCFNQSVLVKEGQKVERGEIIADGPATRYGELALGNNLLLGVIPWNGFNYEDAILISDRIVKEDLYTSIHIKEFSIEVRETKLGPEKVTGDIPNVSEKILNKLDENGIIRIGTYVKPGDILVGKVTPKSEGDITPEFRLLTSIFGEKAKDVKNNSLKVPHGTEGTVIDVQRITKEDVGNLSPGVEEILKVYVAKKRKLKEGDKMAGRHGNKGVVAKILPVEDMPYLADGTPLDICLNPLGVPSRMNIGQLMESQLGLAGKYLGESYNVPVFESATNEQIQEKLKTAGFNPTSKEILYDGYTGEPFENEVMVGVIYMLKLHHLVDDKMHARSTGPYSLVSQQPLGGKAQFGGQRLGEMEVWALEAYGAAHTLQELLTVKSDDMSGRVKIYENIVKGVPTNVSGIPESFNVLMQELRGLGLDLSIYDDAGNQVPLTEKEEELINKS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: UL88_HCMVA
Sequence: MMEAAAAAAAAFRPEERPTPGWHDAALLMDDGTVREHAFRNGPLSQLIRRVLPPPPDAEDDVVFASELCFYCSGRFNRRSSVFSIYWQKHSDLVYALTGITHCAKLVVECGQLGSSRLRWRDGDASGEERRGDDDSRDELYDVPGIYMIRVNDGGSTGPRHVIWPGTSVLWAPDVVITTVQRRISAARALVNTFRQYFFLLERRSHEELVLCPPEMEERLAPLLQSATRGDSDMFDGVVASAYHRLRMSNIPRSSARLLEHCVGLAGAKKLLLLDVPRLENYFLCQVCLYELDEDEMGEEMLGMLAGKPEDAAVSGASGGFLLHRKTMKLAACLCLLLNSLHLHQEALEALDPPPPRVEENDLVNVVLRRYYRSHGGVQARTLAAARALLADYAETFSPLGSFTRLGYDRLVSADAGVSRRHLVALLRA
What is the function of this protein?
Plays a role in incorporating a subset of tegument proteins into the virion.
What are the official names of this protein?
Protein UL88.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U59/UL88 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Note=Accumulates in a juxtanuclear location reminiscent of the viral cytoplasmic assembly compartment.
Protein: Y1135_HAEIG
Sequence: MTTEIKKLDPDTAIDIAYDIFLEMAGENLDPADILLFNLQFEERGGVEFVETADDWEEEIGVLIDQEEYAEVWVGLVNEQDEMDDVFAKFLISHREEDREFHVIWKK
What are the official names of this protein?
UPF0263 protein CGSHiGG_01135.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: ARP2_ACACA
Sequence: MTDSSKVIVCDNGTGFVKCGFARSNFPASIFPSMVGRPILRSEEKFDNVEIKDIMVGDEASKLRSMLQITYPLDNGIVRNWEDAEHVWNYTFFEKLKVDPKDCKILLTEPPMNPLANREKMVQVMFEKYGFKAAYIAIQAVLTLYAQGLLTGVVVDSGDGVTHIVPVYEGFSLPHLTRRLNVAGRDVTRYLIKLLLLRGYVFNRTADFETVRQIKEKFCYVGYDLELEKRLALETTTLVEKYTLPDGRVIPIGAERFEAPECMFNPALVDQESVGVGELVFDCINKADIDTRAEFYNHIVLSGGSTMYPGLPSRLEKEIKRLYFERVAKGNKVSMQKFKCRIEDPPRRKHMVFLGGAVLAEIMKDKTAFWMNKSEYEEQGPRVLRKCF
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).
What are the official names of this protein?
Actin-related protein 2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection.
Protein: PAND_HELPY
Sequence: MTFEMLYSKIHRATITDANLNYIGSITIDEDLAKLAKLREGMKVEIVDVNNGERFSTYVILGKKRGEICVNGAAARKVAIGDVVIILAYASMNEDEINAHKPSIVLVDEKNEILEKG
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C16_MOUSE
Sequence: MATCSRQFTSSSSMKGSCGIGGGSSRMSSILAGGSCRAPSTCGGMSVTSSRFSSGGVCGIGGGYGGSFSSSSFGGGLGSGFGGRFDGFGGGFGAGLGGGLGGGIGDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLEVKIRDWYQRQRPTEIKDYSPYFKTIEDLKSKIIIATQENAQFTLQIDNARLAADDFRTKYENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDVEAWFLRKTEELNKEVASNSDLIQSNRSEVAELRRVFQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLISSVEEQLAQLRCEMEQQSQEYNILLDVKTRLEQEIATYRRLLDGENIHSSSQHSSGQSYSSREVFSSSSRQPRSILKEQGSTSFSQSQSQSSRD
What is the function of this protein?
Epidermis-specific type I keratin that plays a key role in skin (PubMed:22336941, PubMed:24218583).  Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance (PubMed:24218583).
What are the official names of this protein?
Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.