PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_RHOP2
Sequence: MIRNSTKPAKAAPGKAKTTPKAAKSAATSSKATGTAQAVKASPAKGLGKGVIAVAPPSFRRERALIKRGIWPVAGCDEAGRGPLAGPVVAAAVVLDPKRVPKGLDDSKRLSAEKREELFEEICASAQVSVACASPERINRDNILRASLWALTRAVHALPDLPQHVFVDGRDRLATRCESEAVIGGDGLIASIAAASIIAKVTRDRLMCRLAQDCPGYGFEQHKGYGVPEHLAALARLGPSVHHRRFFAPVAAAWQKIEGAPAEPTGLTGDLFGTPADSGHAATL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_STAAM
Sequence: MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS2_HUMAN
Sequence: MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGELTKKDVKLAKFIEKAAASV
What is the function of this protein?
Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase 2, PHS 2, 4-alpha-hydroxy-tetrahydropterin dehydratase 2, DcoH-like protein DCoHm, Dimerization cofactor of hepatocyte nuclear factor 1 from muscle, HNF-1-alpha dimerization cofactor.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: THII_LACP7
Sequence: MYKAFLIKYAEIGLKGKNRHIFENALKDQIRFNLNKLGNFEVSREQGRVFVECPDDFDYDETVAALQRVFGITGISPVIVINSTDWEDIKQEVGDYVEKFYGRKPFTFKVEAKRGNKQYPIQSPEICSKMGAYLLDRFPELSVDVHTPQEYITVEVRNKAYVYSNTLKGPGGMPVGTGGKAMLLLSGGIDSPVAGYMISKRGVTIEATYFHAPPYTSERAKQKVVDLAKIISAYTGPIKLHVVNFTDIQLYIYEKCPHEELTIIMRRYMMKIAESIANRSKCLGLITGESIGQVASQTMQSLAATNAVCTMPVYRPLIGMDKQEIIDISERIGTFETSVLPFEDCCTIFVAKHPVTRPILSVIEKNELNLSEKIDELVKTALETREVITVK
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST1A_DANRE
Sequence: MADELERVRISAAELRAQASSFNIHGDDVKDLREEGKKQRQRDSKRPDLQLYKPGVGHPNRRMDSVEGAGSDTLIQPDGFGNDPKMSDESPTSPGCSYMPGTGNEDYLNDHSKPETNHKTDGHIGGDKHKLVDENAVKIIERAGTPKSPKQSRKMRKPDRQIYQPGGRRSQGNKEVGASKELDRDRSREEEVDGKSIETPLKCEKEEKRKNRRGKNDRKKQASVETPSANKTENAVENISNKVSNLHLETVESKDRDRQDDTNQIKHSEEGRKIQTGGANRGMGEDKKKERGNGKSRPGKEKGNNQVFDKKEEGEAGGKASEAPHLEGRKQRNFGAKEASRDQNLNHEKQQGNRPKEKGKPSERTDSKRVNAASKRYSQSDIRRPRNRTYSTSSASSGTSMDGLAEAERLKAEGQQFSARTLERATGQREFVRGGQTRSRRRTARTLSSTDSLEENEVWEREGRRSRAAEEAKSSTRKEGGILRVSLDKREEQASRKSTRGRGRGILVLPAHTDLTQTPDPAPPLGGMRGGMGLGRGRGGRGGGTRRLWDPNNPDKKPALVSSQQSQHASQHQALYLQQGGCGPLHFLDTDDETVGSPPVRQGEFFQNQQAAAMAYYKFQNSDNPYCYPVSANSPNTPPRYPYPYQIPYQIPGSNGMYPASAMTSFYGPYGQGGPGYPSPTVSALTPEEAEVQTRGELGKFLRLADSQELQLSNLLSRERLSQEGLERMAQLRAELLTIYERVILTDIEFSDSQNVDQTLWKNVFYQVIERFRQLLKDQNSDTAPQIKTMLMTILEEGAVFFDSLLQKLQSVFQFKLQDYMDCMAIRARPLRKTVKYALISAQRCMICQGDIARYREQASESANYGKARSWYLKAQQIAPKNGRPYNQLALLAVYTKRKLDAVYYYMRSLAASNPILTAKESLMSLFEEAKRKADQVERRLKQDSDGSAHGPKGHTGGRRGEDAARVEIWIRPSEVSGTSRPTGSESGKDSEQDGELGALSASDLNKRFILSFLHAHGKLFTKVGMESFPAVANRVLLEFRALLQHSPSPLGSTRMLQIITINMFTIYNAQIRAKGQGETRSALEEQAISLGLAMFGLLVQRCTELLKETPTEPIPAEELGEFDEMDDEEGMVRVSVFPHDLRELLPSMKVWSDWMLGHPEKWNPPPCSMQGSPDVWQCLADLCNSFSRVYHGEVLLYKADADGEGDEELRVLQLEEDKMLSGFVPLLAAPQDACYTDQGTDAAIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYISMAAPLTPSINTENKAQEQEDDVIVEESSLSASEGEIDGEMEGDGSEDDIRELRARRHALAHKLAQQQKRRDKIQAVLQTGGQLEIEVRPFYLVPDTNGFIDHLEGLRKLLACGTYILVVPLIVITELDGLAKGQDSREGVGNGAHARQVQDRARAAVMFLEKAFESRDPSIRALTSRGNTLESIAFRSEDTSGQKGNNDDVILSCCLHYCQDKAKDFMPAERNGPVRLRREVVLLTDDRNLRVKALTRNVPVRDIPAFLIWAKVG
What is the function of this protein?
Plays a role in nonsense-mediated mRNA decay.
What are the official names of this protein?
Telomerase-binding protein EST1A, Ever shorter telomeres 1A, Nonsense mediated mRNA decay factor SMG6, Smg-6 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, telomere. Cytoplasm, cytosol.
Protein: RL33_SALSV
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NADK_ECOSE
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAUT_NAUMA
Sequence: IPDLASSRSTLPVLTKGPTGLLGPRGPYGPLQRFNIELSARGPAAVVGVLGKSFDSWLTKLGLPGPQGRPGPPGPGCRFALSNQCIKLAVEFAGQSKFSSFLANEGKKEGPEGEEGPRTEFDGAYFAGGKFPVVGKPFPQLKVFHAEPPFPTSRSTYGPSGSQPGKKGVVTPFKGNQPLKFNDFLVESDSRCPPDDSSFERSPAVSGHSSPATLNSRMKPAGFPGKGNGAPLKNGIASDPLENLKNRLGSCFPDVLDEPPTSPFFTGPSGYTSDGLNKTPTVSKTLTAAGDPGPGAGKVLESSKTDLVALQGEFQR
What is the function of this protein?
Involved in nacre formation.  Affects morphology of calcite crystals in vitro but does not inhibit their formation.  Binds chitin.
What are the official names of this protein?
Nautilin-63, N63.
What are the subcellular locations of this protein?
Secreted.
Protein: MSA2_PLAF9
Sequence: MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMEESKPPTGAVAGSGAGAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGNGANPGADAERSPSTPATTTTTTTTNDAEASTSTSSENRNHNNAETNPKGKGEVQKPNQANKETQNNSNVQQDSQTKSNVPRTQDADTKSPTAQPEQAENSAPTAEQTESPELQSAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GAR3_HUMAN
Sequence: MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVFETKSI
What is the function of this protein?
May be involved in RNA biogenesis.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 3.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus. Nucleus, Cajal body.
Protein: UBID_BORBR
Sequence: MKYRDLRDFLAQLERQGELKRITAPVSTRLEMTEIADRVLRAGGPALLFENARHNDAPADMPVLANLFGTPRRVAWGMGADDVGALRETGELLASLREPEAPKGLRDALAKVSMLKAALWDMSPKTVRSAACQEIVWEGADVDLGRLPIQTCWPGDVAPLLAWGLVITRGPNARRQNLGIYRQQPLGPNKLIMRWLSHRGGALDFRDHAQAHPGKPFPIAVALGADPATILGAVTPVPDTLSEYQFAGLLRGSRTEVVKALGSDLSVPASAEIVLEGHLLPADDPRAVAAAVPEGANPPPATGYEMALEGPYGDHTGYYNEQDWFPVFTVDRITMRRNPIYHSTYTGKPPDEPAVLGVALNEVFVPLLRRQLPEIVDFYLPPEGCSYRLAVVSIRKQYAGHAKRVMFGLWSVLRQFMYTKFIVVVDEDIDPRDWTEVVWAMTTRMDPVRDTVLVENTPIDYLDFASPVSGLGGKMGLDATNKWPGETSREWGTPIHMDEAVKRRVDAMWDTLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FOXK2_HUMAN
Sequence: MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN
What is the function of this protein?
Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy (By similarity).  Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context (PubMed:22083952, PubMed:25451922).  Together with FOXK1, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (By similarity).  Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (By similarity).  Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (By similarity).  Together with FOXK1, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (By similarity).  In addition to the 5'-GTAAACA-3' DNA motif, also binds the 5'-TGANTCA-3' palindromic DNA motif, and co-associates with JUN/AP-1 to activate transcription (PubMed:22083952).  Also able to bind to a minimal DNA heteroduplex containing a G/T-mismatch with 5'-TRT[G/T]NB-3' sequence (PubMed:20097901).  Binds to NFAT-like motifs (purine-rich) in the IL2 promoter (PubMed:1339390).  Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus (PubMed:25805136).  Also binds to HIV-1 long terminal repeat.  May be involved in both positive and negative regulation of important viral and cellular promoter elements (PubMed:1909027).
What are the official names of this protein?
Forkhead box protein K2, G/T-mismatch specific binding protein, nGTBP, Interleukin enhancer-binding factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MTFR1_MOUSE
Sequence: MLGWIKCLMRMWFQRVGVSMQSVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSHATEWSPAHSGEDAVASFADVGLVATEEGECSIRLRAEVSSKPPHEDDPPCFEKPPSRHTSFPSLSQDKPSPERTLASEEALQKISALENELAALRAQIAKIVTLQEQQSPSAGCLDSSTSVTVAPPPPPPPPPPPLPLVLHQSTSALDLIKERREQRLSAGKTLATGHPKKPDMPNMLEILKDMNSVKLRSVKRSEKDVKPRPADTDHAAFIAEALKKKFAYRHNSQGETERGIPKPESEATSEPALFGPHILKSTGKMKALIENVPDS
What is the function of this protein?
May play a role in mitochondrial aerobic respiration.  May also regulate mitochondrial organization and fission.
What are the official names of this protein?
Mitochondrial fission regulator 1, Chondrocyte protein with a poly-proline region.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=May be associated with the inner and the outer mitochondrial membrane.
Protein: PLSX_RHILO
Sequence: MIRISIDAMGGDHGPAVVIPALMTVATRRPDIRFVIYGREELVRPELAKFPKLAEVSEFFHCEIAVRMDDKPSQALRHGRWKSSMWKAVEAVKSGAADACISAGNTGALMAMSKFCLRTMATIDRPAIAALWPTLRGESVVLDVGATIGADAHQLIDFAILGTGMARSVFGVARPTVGLLNVGVEEIKGQEEVKEAGRMLREANMASMNYHGFVEGDDIGKGTVDVVVTEGFAGNIALKTAEGTARQIAGYLRAAMSRTLMAKIGYVFAKSAFDRLREKMDVGRSNGGVFLGLNGIVVKSHGGADSDGFAAAIELGYDMVRNNLLDRIEADLDLFHARNPHALSSRKSDVVTDAKE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DXR_PARPJ
Sequence: MQKRLTLLGSTGSIGDSTLDVVARHPERFSVYALTAHRNGDKLVEQCLRFQPEVAVVGDADTAASVAAKLREAGCKTEITYGPQALVDVSKSDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKEALVMSGAIFMDAVRDNGAVLLPVDSEHNAIFQCLPREAALHGGVSKIILTASGGPFRTREPATLVEVTPDEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWLFNLPGERIEVLIHPQSVIHSMVSYADGSVLAQLGNPDMRTPIAHALAFPDRVDSGVAQLDLLQVASLSFEKPDYTRFPCLALAVKALAEGGLASAALNAANEIAVEAFLARQIGFMAIAQVVDAVLNALPNRSAHALEDVIEADAAARRAAAEFIARLPDGARRTERAVQ
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: C3H21_ARATH
Sequence: MPPKQQPKADLAKKQKQVEDKTFGLKNKNKSKNVQKYVQSLKQSVQPKPDATKAAAKKKKEEEKAREQELNELFKVAISQPKVPVGVDPKSILCEFFKAGQCQKGFKCKFSHDLNIQRKGEKIDIYSDTRDEDGDMDEWDQETLEKVVESKKNEYNQNKPTDIVCKYFLDAVEKKQYGWFWSCPNGGKECHYRHALPPGYVLKSQMKALLEEESSKKLAVEDEIENERAKLQTATQMTPALFMEWKRKKIAERDAGLAASQAERAKNDRMSGRELFLSNASLFVDDAEACEEYEREREQEETEQKAKNKEAEAGTSKSSGDAEQSSKEVNEEEEDDDDDDDDLDMDELDELEASLSKTSIQIREPNDEGSS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 21, AtC3H21.
Protein: ENGB_ANASK
Sequence: MPIQVVSADFAKTATRPEEWPRGATPEIAFVGRSNVGKSSMLNALARRKGLARVSSTPGRTRALQFFDLSYRPTPAARPRAIRFCDLPGYGYAKVARAERDRWTAMIEDYLRDRDVLRAVVLIVDARHPPSESDEDAAAFLVSAGRRLVVAATKTDKLPKARRVLALQQVERALGLARGDAVPFSAVEGTGTDALWARLAALAAEEPQTAEAEPPA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NREC_STAA8
Sequence: MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_NITHX
Sequence: MASLKDMRVRIASTKATQKITKAMQMVAASKLRRAQSAAEAARPYAEKMDQVISNIASAAAGSPGAPVLLGGTGKDQVHLLLVCTGERGLSGAFNSSIVRLARERALALMNQGKDVKFFCVGRKGYEQLRRTFEKQIVENVELRSVRQLGFVNAEAIAKKVIARFNAGEFDVCTLFYSRFKSVIAQVPTAQQIIPLEVEAPAANAGPAPFYEYEPEEDEILTRLLPRNLAVQIFRALLENNASFYGAQMSAMDNATRNAGDMIRKQTLVYNRTRQAMITKELIEIISGAEAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL15_CLOBJ
Sequence: MKLHELKAAEGANKASKRVGRGTGSGLGKTSGRGQNGQNSRSGGGVRPGFEGGQMPLYRRLPKRGFKNIFAKEYAAINLDRLNCFEDGTVVTPELLVEKRVVKKVKDGVKILGNGNIEKKLTVKAAKFSKSAIEKIEAAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: XRS2_YEAST
Sequence: MWVVRYQNTLEDGSISFISCCLQAFKTYSIGRSSKNPLIIKNDKSISRQHITFKWEINNSSDLKHSSLCLVNKGKLTSLNKKFMKVGETFTINASDVLKSTIIELGTTPIRIEFEWINEVWNIPPHLTQFRTMLSEYGISTEISINDIPANLMISDYPKSEDNSIRELYALVSTIPMKKSRFLMELCNTLLPTSKTNLKFDEMWNDMISNPEYNVFDFDPNILLSKFMRLNNIRVLTTIKSEPRLSSLLRTFNINLFAFDNIDSLYKYVDSLEASTEYLILTTTDKKENGKILCTIKTMLTSIIDGTLSAVINMKGASSRTLDNGKFDQISEGMSTILKTSRAPEVEASPVVSKKRKLNRRRVLPLDSLDFFAGGLSTKTLSENRSLTDAKRLNCGAESKTVISSPNIAEADEKHAPFLQNALKPTEDIGKKSGHSSPGAIIVSSPNLGTVNTSEDSLDKSLQSHKLPQPSLPEVAGIGSQTISSNSADYETAAVNSMDDAEVTKNFRVNHHQNIEQPSKNIRKLSNYSREISSPLQENCKSPVKELSIKEKSGTPHAFVEAIQETKNREVKRVKSTIVELKDEELSEEAINQLKNLAIVEPSNNLLRKSFDSEGNKTSRTTEKWENSLMEPEWHKRKNFKTFVKVRPKSKAHKEEGKNNTQSSDFIRNAAFLITRNYVPLKKYSKKDTTTKWGTEENEDMFALTEMERFGSNTFMSDNINSNTIQKRSQALNRFTNEDSSNEGEEDSFSFSRCSGTAASVQPLKNKIFITDEDDLGDIDDKSDRLNHRENNRNLFVVKEMNLRPNLSEECSKQSRHSRSATSRSRGSFGASNNGDGDDDDDDGPKFTFKRRKG
What is the function of this protein?
During meiosis is involved in homologous recombination and during vegetative growth it is necessary for DNA repair.  It probably regulates the 5'-3' exonuclease degradation of double strand breaks either at the initiation stage or a later stage.
What are the official names of this protein?
DNA repair protein XRS2.
Protein: COAD_BACC7
Sequence: MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFA1_HUMAN
Sequence: MAPRRNNGQCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIENSFMTDARK
What is the function of this protein?
Restin potently inhibits angiogenesis.
What are the official names of this protein?
Collagen alpha-1(XV) chain.
What is the protein family that this protein belongs to?
Belongs to the multiplexin collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RNC_DEHM1
Sequence: MLDLTELEKSLGVKFENLSLLEQALIHTSWVNENPNHLSGSNERMEFLGDAVLGVIFADRLYHDFPDIQEGDLTRFRSLLVRRESLVRVALGINLGKYLYLGRGEDASKGRFKPANLAGAFEAVLAAIYLDKGIDATREVIFRLFKTEMERVQTLSSNIDYKSRLQELVQAQFQLTPRYRIIDFSGPEHNHLFIAEVYTEDKVLAEGSGRSKKEAETSAAKEALQQFENSFTAEDNI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_MYCPU
Sequence: MRVKGGTVTRARRKKWLKLAKGYWGHKSIGYKVAKQAVVKSWTYAFRDRKQVKRNFRKLWISRINAAVRPLGMSYSQFINGLKKANVKINRKMLSELAIREMKTFEMLVSISKSSK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DADA_NEIM0
Sequence: MKVLVLGAGVAGVSSAWYLAEAGHEVTVIDRAEGVAMETSFANAGQLSYGYTTPWAAPGIPTKALKWLFKSHPPLLFRPDGSLYQIEWLWQMLQNCTAAHYQTNKERMVRISEYSREMFRRFEAQTGMNFEERKKGTLQIFRQTKEVEAAEQDIAVLERYGVPYRRLKPEECAEFEPALARVTAKIASGLHLPADATGDCRLFTENLYKLCQEKGVRFHFNQTISRIDHNGLRIKTVETETGRFEADAVVCALGCFSRTVLAQLDLNLPIYPVKGYSLTLPVTNSDGAPVSTVLDESYKVAITRFDNRIRVGGMAELSGYEIKLPEKRRETLALVVNDLFPEGGDLSQASFWSGLRPMTPDSTPLIGRTRFDNLFLNTGHGTLGWTMSLGSAKLTADIVSGKDTEIRSDDLSLSRYQA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.