PharMolix/UniProtQA huggingface dataset:
Protein: DTD_YERPG
Sequence: MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PROMM
Sequence: MSSSFFKKRLSPIKPGDPIDYKDVDLLKKFITDRGKILPRRLTGLTSKQQRDLTNAVKRARIIALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: IAP_ASFP5
Sequence: MFPKINTIDPYISLRLFEVKPKYVGYSSVDARNQSFAIHDIKNYEKFSNAGLFYTSPTEITCYCCGMKFCNWLYEKHPLQVHGFWSRNCGFMRATLGIIGLKKMIDSYNDYYNNEVFVKHKNRVYTHKKLEDMGFSKPFMQFILANAFIPPYRKYIHKIILNDRYFTFKFAAHLLSFHKVNLDNQTTYCMTCGIEPIKKDENFCNACKTLNYKHYKTLNFSVKL
What is the function of this protein?
Prevent apoptosis of host cell by inhibiting caspase-3/CASP3 activation to promote the viral replication.  Induces also the activation of host NF-kappaB.
What are the official names of this protein?
Inhibitor of apoptosis protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus IAP family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Probably accumulates in the perinuclear cytoplasmic viral factories. Found in association with viral nucleoid.
Protein: MALT_PHOLL
Sequence: MLIPSKLSRPVRLNNTVLRERLLIRLNESSNYRLVLITSPAGYGKTTLVSQWAAGQDNLGWYSLDESDNQPERFASYLIAALQQATQGHCVKSEVLAQKHQYANLPALFAQLFIELSEWRRPIFLVIDDYHLIVNNMIHEAMRFFLRHQPENLTLTILSRNLPSLGVANLRVREQLLEIDSQQLAFDYQETQQFFDKRLTTSLDADDCKRLCNEVAGWATALQLIALSARQSCDAAELSAKRLSGINAGHLSDYLVDEVLNQVGSSTREFLLRSSILRSMNDGLIVRLTGEENGQQRLEETERQGLFIQRMDDSGEWFRFHPLFASFLRQRCQWEMALQLPELHRAAAEGWLAQGYPGEAIHHALAAGDTAMLRDILLQHAWSLFNHSELSLLEECMNALPYEQLLESPRLVLLQAWLAQSQHRYSEVNTLLNQAEQALQQKQIAIEPDLLAEFDALRAQVAMNSGKPEMADKLAKQALAALLPQNEYSRIVATSVEGEVLHCRGELADALARMQQTEQLARRFHVHHYALWALLQQSEILLAQGYLQTAYETQNKAFELIREQHLEQLPMHEFLLRIRSQLLWCWSRLDEAEEAARRGLEVLSNFQPQQQLQCLTQLAKCSLTRGDIDNARRYLARCENLLSNGQYHRDWRTNTDKLRVIIWQSMDDKSAAIRWLAQTERPESVSNHFNQGQWRNIARAQILLGLYDEAESILDTLNQHARELQLISDLNRNLLLCNLLYWHIGRKSEAQSALIEALSLANRTGFISHFVIEGELMAQQLRQLIQLNTLSELELHRAQRILRDINRQHRHKFAHFDESFVTQLLTHPDVPELIRNSPLTQREWQVLGLIYSGYSNDQIAAELDVATTTIKTHIRNLYQKLGIANRQEAIQQAQQLMQMMGLGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: RL36_MESM1
Sequence: MKVRASVKPMCKDCKIIKRKGAVRVICKTSPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: LUKE_STAAU
Sequence: MFKKKMLAASLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQFDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGRGYELTKRLIWPFQYNIGLTTKDPNVSLINSITLPKTKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQNSKSVKWGVKANKFVTPDGKKFAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPSFITTLSHEKGSKLIRVNLKFSYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYKVNWKTHEIKVKGHN
What is the function of this protein?
Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells.  LukE-LukD is as effective as the Panton-Valentine leucocidin (PVL) for inducing dermonecrosis when injected in the rabbit skin, but not hemolytic and poorly leucotoxic on human blood cells compared to other leucotoxins expressed by S. aureus.
What are the official names of this protein?
Leucotoxin LukE.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_STAES
Sequence: MARDFSLKNTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAQWQGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAAPIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIDEIEIPEDHKERAEEARAQLIEAVAENNDDLMEKYLGDEEISVDELKDAIRQATTDVEFYPVLCGTAFKNKGVQLMLNAVIDYLPSPLDVKPIIGHRANNPDEEVVAKPDDSAEFAALAFKVMTDPYVGKLTFFRVYSGTLSSGSYVKNSSKDKRERVGRLLQMHANSRQEIDTVYSGEIAAAVGLKETGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKQPAQVQGKFSRQSGGRGQYGDVHIEFTPNETGGGFEFENAIVGGVVPREYIPSVEQGLKDAMENGVLAGYPLIDVKAKLFDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTARRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_PODAN
Sequence: MADSAPRLAALDDSIVSRLPSYSQSLFAAKTAHELSFSAIAEHLGRSEVAVAALFYGQATASPEDITKLAELLSLPEAQLRKDLGTGFPDRGRSGPMPPVEPLIYRLYEVVQNYGYAFKSVINEKFGDGIMSAICFDTKVEKETVEGADWVVITLRGKWLPFTRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: HSLV_RICRO
Sequence: MSDNLSLHGTTILCLKKNEEIIIAADGQVSHGNTVLKSTARKLRTIANNKIIAGFAGSTADGLALFEKLAVKIEQHKHNLLRSAVELAKDWRSDKYLRRLEAMMIVADRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSYENNLTAEEIALKSMNIAADLCVFSNHNIIMEKVV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_CHRVO
Sequence: MWKSILAIAIGAAAGALLRWFLGLRLNSLFPSLPPGTLAANLVGGYIIGVAVALFADMPMLSPLWRLLIITGFCGGLTTFSTFSAEVVDLLRQGQLQPAFAAIAVHVSGSLLMTMAGIASWQWLRR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACPS_STRPM
Sequence: MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLSYLAGRWAGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABK2_DICDI
Sequence: MDNNNNKKLFNTHGSAFDDSKIYFRDVDCGVLCFNIHNEQSFNNLNHWMSLFNENVPFVLIGTKSDIERTEKSISKERIEQWCKQIEDQGIVKEKIHYFETSAKLSTNIIEAYETIVKIALNQYKNKQKNSINISIEPEKPKGICWW
What are the official names of this protein?
Ras-related protein RabK2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ADIC_SALTI
Sequence: MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLAATGGIAIYGWLVTIIGALALSMVYAKMSSLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDPLVLTLTCVAVLWIFVLLNIVGPKMITRVQAVATVLALVPIVGIAVFGWFWFKGETYMAAWNVSGMNTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLLIVGVLMTIFQFSSMSPNAAKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPLYLLITFVAFVYCIWAVIGSGAKEVMWSFVTLMVITALYALNYNRIHKNPYPLDAPVKQD
What is the function of this protein?
Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach.  Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons.  Probably undergoes several conformational states in order to translocate the substrate across the membrane; keeps the substrate accessible to only 1 side of the membrane at a time by opening and closing 3 membrane-internal gates.
What are the official names of this protein?
Arginine/agmatine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_BORBZ
Sequence: MKTKLGFNRLSRKSSHRRALLKNMVISFFKHEKISSTKTKLFEVKRFAERLITRAKVDTVHNRRELSKFIHDKYILNKLFTKISPVFRQRSGGYTRMIKLGKRYGDAAEMAILELVEKPLKVE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RIMM_MYXXD
Sequence: MTATSPYLELGYVARAHGLRGEVAIRALDPASETLDTVDRIWVRTRAGVEREMRLEALRPTPKEDIVVLEGVESRNDAEALVGAKVFVFREDLEPPAEGEFFQGDLVGLDAVDANGNALGRVEEIWTTGEVPNLVIRASGREELVVPFADEFVPTVDLEARRIVIHPPEYVEAGRKGAESGGGPEDAE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B_EMENI
Sequence: MPPKAAEKKPSTGGKAPAGKAPAEKKEAGKKTAAAASGEKKKRGKTRKETYSSYIYKVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CAN2_CANAL
Sequence: MFEVGEKYPVESSSSSNDIESRGVQPITSLKDNKSIGMIEKDNDDLSCEQYSTCDEVKRDLKARHVSMIAIGGTIGTGLFISTGSLLHTTGPVMSLISFLFVTTLAYSVTQSLGEMTTYIPVSGSFAQFITRWVSKSCGAANGWLYWFSWAITFALELSVVGQVIQYWTDAVPLAGWISIFFVLLTTFNLFPVKYYGEVEFWIASTKVIAIVGWLIYAFCMVCGAGKTGPVGFRYWRNGYAWGDGMIVSNNGKYAISFINGLINAVFTFQGTELVAVTAGEASPRAIRSAIKKVMFRILVFYVLCMLFIGLLVPYNDPKLTQDGGFTRNSPFLIAMENSGTKVLPHIFNAVIVTTIISAGNSNVYSGSRILYGLAQAGVAPKFFLKTNKGGVPYFAVLFTAAFGALGYLACSEDGNKAFTWLLNIIATAGLIAWGFISVSHVRFMNVLRKRGLSRDILPYKAFFMPYSAYYAIIIIFIVVLIQGFTVFWDFNASDFFTAYISVILFVVLWIGFHFFFYGFGKDSFKWENILIPLDDCDIDSGVRDINDAEFDVPEPKNVWERFWLLIA
What is the function of this protein?
Probable permease for arginine and lysine.
What are the official names of this protein?
Probable lysine/arginine permease CAN2, Basic amino acids permease CAN2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROQ_ALISL
Sequence: MSTQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYELIEAIHNAYQRIDFIIINPAAFTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLSDKAVGVICGLGADGYEFALKAAVKRLRSN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: XGPT_SALEP
Sequence: MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU6M_CYPCA
Sequence: MTYFMFLLLMALVVGLVAVASNPTPYFAALGLVVAAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYAALAAEPFPEAWGSRSVLGYVLVYLLGVGLVAGIFWGGWYEGSWVVVDGLKEFSVLRGDISGVAVMYSSGGGMLVICAWVLLLTLLVVLELTRGLSRGALRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL10_SHEEP
Sequence: MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS
What is the function of this protein?
Component of the large ribosomal subunit.  Plays a role in the formation of actively translating ribosomes.  May play a role in the embryonic brain development.
What are the official names of this protein?
60S ribosomal protein L10, Protein QM homolog, Ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: VP4_ROTBN
Sequence: MASLIYRQLLTNSYTVELSDEIQEIGSTKTQDVTVNPGPFAQTNYAPVNWGPGETNDSTTVEPVLDGPYQPTTFNPPVSYWMLLAPTNAGVVVEGTNNTNRWLATILIEPNVQQVERTYTLFGQQVQVTVSNDSQTKWKFVDLSKQTQDGNYSQHGSLLSTPKLYGVMKHGGKIYTYNGETPNATTGYYSTTNFDTVNMTAYCDFYIIPLAQEAKCTEYINNGLPPIQNTRNIVPVSIVSRNIVYTRAQPNQDIVVSKTSLWKEMQYNRDIVIRFKFANSIIKSGGLGYKWSEVSFKPANYQYTYTRDGEEVTAHTTCSVNGINDFNYNGGSLPTDFVISKYEVIKENSFVYIDYWDDSQAFRNMVNVRSLAADLNSVMCTGGDYSFALPVGNYPVMTGGAVSLHSAGVTLSTQFTDFVSLNSLRFRFRLSVEEPPFSILRTRVSGLYGLPAARPNNSQEYYEIAGRFSLISLVPSNDDYQTPIINSVTVRQDLERQLGELRDEFNNLSQQIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKRFKKSSLANSVSTLTNSLSDAASSISRSASVRSVSSTASAWTEVSNITSDINVTTSSISTQTSTISRRLRLKEMATQTDGMNFDDISAAVLKTKIDKSTQLNTNTLPEIVTEASEKFIPNRAYRVKDDEVLEASTDGKYFAYKVETFEEIPFDVQKFADLVTDSPVISAIIDFKTLKNLNDNYGISRQQALNLLRSDPRVLREFINQDNPIIRNRIESLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: CH60_FRATN
Sequence: MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVAAGMNPMDLKRGIDKATAKLVEELKALSKPCSDPKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQENMTTDLENPYILIVDKKISNIRDLLPVLEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPGFGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIKANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQKALDGLTGENDDQNHGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVEMGILDPTKVTRSALQHAASIAGLMITTEAMVGEIKEAAPAMPMGGGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XB3_ORYSJ
Sequence: MGHGVSCARTGDEHDFFRAAQLGDLDALAALLAADPSLARRATLYDRLSVLHIAAANGRIEVLSMFLDRGAPPDAVNRHKQTPLMLAAMHGKIDCVLKLLQADANILMFDSVHARTCLHHAAYYGHVDCLQAILAAAQTTPVADSWGFARFVNVRDDHGATPLHLAARQGRPGCVQVLLENGAIVSALTGSYGFPGSTSLHLAARSGNLDCIRKLLAWGADRLQRDSAGRIPYSVALKRNHGACAALLNPTSAEPMVWPSPLKFISELEPEAKALLEAALMEANREREKKILNGTKYSLPSPSPGDDSADDDACSEVSDTELCCICFDQACTIEVQDCGHQMCAPCTLALCCHNKPNPTTLTPPSPACPFCRGSISRLVVAQTRSACDPDKPSSLQLTRKRSRRSHNLSEGSSSFKGLPSAMGSFSKLGRGSSRMADSDSSNLDKPEHDL
What is the function of this protein?
E3 ubiquitin-protein ligase required for full accumulation of the LRR receptor kinase XA21 and XA21-mediated disease resistance.  Binding to XA21 may stabilize the receptor kinase and maintain its protein level.  Autoubiquitinated in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase XB3, Ankyrin repeat domain and RING finger-containing protein XB3, RING-type E3 ubiquitin transferase XB3, XA21-binding protein 3.
Protein: P2RX7_MOUSE
Sequence: MPACCSWNDVLQYETNKVTRIQSTNYGTVKWVLHMIVFSYISFALVSDKLYQRKEPVISSVHTKVKGIAEVTENVTEGGVTKLGHSIFDTADYTFPLQGNSFFVMTNYVKSEGQVQTLCPEYPRRGAQCSSDRRCKKGWMDPQSKGIQTGRCVPYDKTRKTCEVSAWCPTEEEKEAPRPALLRSAENFTVLIKNNIHFPGHNYTTRNILPTMNGSCTFHKTWDPQCSIFRLGDIFQEAGENFTEVAVQGGIMGIEIYWDCNLDSWSHHCRPRYSFRRLDDKNTDESFVPGYNFRYAKYYKENNVEKRTLIKAFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLATVCIDLLINTYSSAFCRSGVYPYCKCCEPCTVNEYYYRKKCESIMEPKPTLKYVSFVDEPHIRMVDQQLLGKSLQVVKGQEVPRPQMDFSDLSRLSLSLHDSPLTPGQSEEIQLLHEEVAPKSGDSPSWCQCGNCLPSRLPEQRRALEELCCRRKPGRCITTSKLFHKLVLSRDTLQLLLLYQDPLLVLGEEATNSRLRHRAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKTEGQYSGFKYPY
What is the function of this protein?
Receptor for ATP that acts as a ligand-gated ion channel.  Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules.  Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.  In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells.
What are the official names of this protein?
P2X purinoceptor 7, P2X7, ATP receptor, P2Z receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMC_YERPP
Sequence: MNQRPIQTATLSWNEQGTPVSEQFGDIYFSNEDGLEETHHVFLKGNGFPARFASHPQQSCIFAETGFGTGLNFLTLWRDFALFRQQSPNATLRRLHYISFEKYPLHVADLASAHARWPELASFAEQLRAQWPLPLAGCHRILLADGAITLDLWFGDVNTLLPTLDDSLNNQVDAWFLDGFAPAKNPDMWNEQLFNAMARMTRPGGTFSTFTAAGFVRRGLQQAGFNVTKVKGFGQKREMLTGTLPQQIHAPTAPWYHRPAATRCDDIAIIGGGIVSALTALALQRRGAVVTLYCADAQPAQGASGNRQGALYPLLNGKNDALETFFTSAFTFARRQYDQLLEQGIAFDHQWCGVSQLAFDDKSRGKIEKMLHTQWPVEFAEAMSREQLSELAGLDCAHDGIHYPAGGWLCPSDLTHALMMLAQQNGMTCHYQHELQRLKRIDSQWQLTFGQSQAAKHHATVILATGHRLPEWEQTHHLPLSAVRGQVSHIPTTPVLSQLQQVLCYDGYLTPVNPANQHHCIGASYQRGDIATDFRLTEQQENRERLLRCLPQVSWPQQVDVSDNQARCGVRCAIRDHLPMVGAVPDYAATLAQYQDLSRRIQHGGESEVNDIAVAPVWPELFMVGGLGSRGLCSAPLVAEILAAQMFGEPLPLDAKTLAALNPNRFWIRKLLKGRPVQTRSPATQESSR
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.