PharMolix/UniProtQA huggingface dataset:
Protein: IF1_CHLCH
Sequence: MAKEESIEIEGVIVDALPNAQFKVKLENGLEVLAHVSGKIRMHYIRILPGDKVKVQISPYDITKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYRM2_MOUSE
Sequence: MAASRLPPAALTLKQFMRRQQVLLLYRKILRAIRQVPSDSDRKYLQDWAREEFKRNKSATEEDTIRMMITQGNMQLKELERTLALANS
What is the function of this protein?
Involved in effecient integration of the N-module into mitochondrial respiratory chain complex I.
What are the official names of this protein?
LYR motif-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
Protein: WNT7A_AOTTR
Sequence: MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity).  Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development.  Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity).  Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes.  Required for normal neural stem cell proliferation in the hippocampus dentate gyrus.  Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation.  Promotes formation of synapses via its interaction with FZD5 (By similarity).
What are the official names of this protein?
Protein Wnt-7a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: PROB_ECO5E
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PELA_NEOFI
Sequence: MKYQGLLAIAGCIASASAVSVSGAAEGFAKGVTGGGSATAVYPSTTAELVSYLGDSEARVIVLTKTFDFTGTEGTTTATGCAPWGTASACQLAINQNDWCTNYEPDAPSVSVTYDNAGTLGITVKSNKSLLGSGSSGVIKGKGLRIVSGASNIIIQNIAITDINPKYVWGGDAITINNADMVWIDHVTTARIGRQHLVLGTSASNRVTISNNYFNGVSSYSATCDGYHYWGIYLDGSNDLVTMKGNYIYHFSGRSPKVQGNTLLHAVNNYWYDSSGHAFEIGSGGYVLAEGNVFQNIDTIVESPVDGQLFTSPDSTTNKVCSTYLGHVCQVNGFGSSGTFSQADTGFLSNFAGKNIASASAYTVVQSSVPSSAGQGKI
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase A, PLA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCTA_BURP0
Sequence: MKKPFYKVLYVQVIFAIVVGVILGHYYPSLAVDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMQDMKKVGRVGGKALLYFEIVSTCALVLGLAATHILRPGVGFNIDPATLNGKEVASYAAKAHGQSSVDFLMHIIPNTMIDAFAQGEILQILLIALLFGSVLAHLGERGRVVTDFIDGITRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSVVFVLVVLGAIARFTGFSIIRFVGYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRAKLRAALSGNGEAAAGEAARV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EPMA_YERPA
Sequence: MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: SYW_PYRAB
Sequence: MVEDFKVTPWEVEGVVDYNKLIEHFGTSPLTEELLEKTAELTKSELPLFFRRKFFFSHRDYDKVLQDYEEGRGFFLYTGRGPSGPMHIGHIIPFFATKWLQEKFGVNLYIQITDDEKFLFKENLTFEDTKHWAYENILDIIAVGFDPDKTFIFQNSEFTKIYEMAIPIAKKINFSMAKAVFGFTEQSKIGMIFFPAIQIAPTFFEKRRCLIPAAIDQDPYWRLQRDFAESLGYYKTAAIHSKFVPSLTSLSGKMSASKPETAIYLTDSPEDVEKKVWKFALTGGRPTLKEQREKGGEPEKCVVFKWLEIFFEEDDKKLKERYYACKNGELTCGECKRYLISKIQEFLKEHQKRRKKAEKQIEKFKYTGKLAQEMWDKAIPEPLKG
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACMK
Sequence: MRKIGIIGGTFDPPHNGHLLIANEVYHALGLEEVWFLPNQVPPHKQGRNITSVKSRLNMLQIAIEEEAYFSICLEELDREGPSYTYDTMVQLTEKYPDVQFHFIIGGDMVEYLPKWYNIEKLLKLVTFVGVARPGYTLHTPYDIVKVEIPEFAVSSSLLRERYMTKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RL29_RALPJ
Sequence: MKASELRDKDVAGLNQELSELLKAQFGLRMQKATQQLQNTSQLKKVRRDIARVRTVLGQKGNQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LGUL_HAEIN
Sequence: MQILHTMLRVGDLDRSIKFYQDVLGMRLLRTSENPEYKYTLAFLGYEDGESAAEIELTYNWGVDKYEHGTAYGHIAIGVDDIYATCEAVRASGGNVTREAGPVKGGSTVIAFVEDPDGYKIEFIENKSTKSGLGN
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: LYXK_HAEIN
Sequence: MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQKTIRQSSILPQQIKAIGISAQGKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQKFYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHDYLRFCLTEKLYCEETNISESNFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGLFDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEASPTSAGNLEWFVNQFNLPNYDDINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQSHHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTGGPAKSEVWMQMLADISGMRLEIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEALKNLD
What are the official names of this protein?
Probable L-xylulose kinase, L-xylulokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MURE_WIGBR
Sequence: MIKIINLKKFLFPWISTDISKIKLNSIKLNSKKIIKNDIFIALYGNCNHGKNFIFEAIKNGSSIILIETKNILKHGIIYFIKNIPIIYFYNLNYSLSELSGKFYLHPSRYMNVIGITGTNGKTTISHFIAKWLFLLGEKIGIIGTLGYGCLNKMKKSKNTTNSAIKCQKLLNFFLKKNINTVVMEVSSHGLHQNRVNNINFFSAIFSNLSQDHIDYHKNMMQYEQSKWKLFSKLNVYKYIINYDDVIGKNWIKKIPNSIIVSTKKNSIKKFKNLKMYVKDIFFHYFGTKLSISSSWGSCVINTKIFGEFNINNLLLSFVALLTLGYNFKSLANVAENLTMPNGRMKIFYVKKIPRVIVDYAHTPDALEKVLSAIKLHFKKNIWSIFGCGGDRDKSKRRVMGKICDLYSINIILTNDNPRSESETKIFNDIKIGIKNLNKVNIIPSREHAIKFAIDNSNEKDIVLILGKGHEEHQVFKYKKVFFSDQILVNKILYKT
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPJ_YERPS
Sequence: MIGPISQINISGGLSEKETSSLISNEELKNIITQLETDISDGSWFHKNYSRMDVEVMPALVIQANNKYPEMNLNLVTSPLDLSIEIKNVIENGVRSSRFIINMGEGGIHFSVIDYKHINGKTSLILFEPANFNSMGPAMLAIRTKTAIERYQLPDCHFSMVEMDIQRSSSECGIFSFALAKKLYIERDSLLKIHEDNIKGILSDGENPLPHDKLDPYLPVTFYKHTQGKKRLNEYLNTNPQGVGTVVNKKNETIVNRFDNNKSIVDGKELSVSVHKKRIAEYKTLLKV
What is the function of this protein?
Serine/threonine-protein acetyltransferase translocated into infected cells, which inhibits the host immune response and induces cell death by mediating acetylation of target proteins.  Inhibits the MAPK and NF-kappa-B signaling pathways by acetylating protein-kinases such as MAP2K1, MAP2K6, MAP3K7/TAK1 and I-kappa-B kinase (CHUK/IKKA and IKBKB) on serine and threonine residues critical for their activation by phosphorylation, thereby preventing protein-kinase activation.  Promotes pyroptosis, a programmed cell death, in host cells by mediating acetylation of MAP3K7/TAK1: MAP3K7/TAK1 inactivation triggers activation of caspase-8 (CASP8), followed by CASP8-dependent cleavage of gasdermin-D (GSDMD) and induction of pyroptosis (By similarity).  Also able to induce intestinal barrier dysfunction by acetylating and inhibiting host protein-kinases RIPK2/RICK and MAP3K7/TAK1, thereby promoting cell death (By similarity).
What are the official names of this protein?
Serine/threonine-protein acetyltransferase YopJ, Virulence factor YopJ.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase YopJ family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS).
Protein: OPTN_RAT
Sequence: MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKIQVRRLQAEKADLLGIVSELQLKLNSGGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGSRQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII
What is the function of this protein?
Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8.  Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation.  Negatively regulates the induction of IFNB in response to RNA virus infection.  Plays a neuroprotective role in the eye and optic nerve.  Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death.  May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD).  Mediates the interaction of Rab8 with the probable GTPase-activating protein TBC1D17 during Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TFRC/TfR); regulates Rab8 recruitment to tubules emanating from the endocytic recycling compartment.  Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family; targets ubiquitin-coated bacteria (xenophagy) and appears to function in the same pathway as SQSTM1 and CALCOCO2/NDP52.
What are the official names of this protein?
Optineurin, FIP-2-like protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans- Golgi network. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle. Recycling endosome. Note=Found in the perinuclear region and associates with the Golgi apparatus. Colocalizes with MYO6 and RAB8 at the Golgi complex and in vesicular structures close to the plasma membrane. Localizes to LC3-positive cytoplasmic vesicles upon induction of autophagy.
Protein: RBFA_THEAB
Sequence: MRPEYRNKKIEAYIRELIAQAIQKIKEPEFEYLKDYIVISRVLISKDRRFADVFVSVIGNSEQRKKAVELLEKYKGYFRTFVAKNVRLYTAPELRFKEDKGIEESVRINKLLDEIMSKEDENGSDN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECHP_CAVPO
Sequence: MAEYLRLPHSLALIRLRNPPVNAISPAVIHGIKEGLQKAMSDYTIKGIVISGANNIFCAGADIHGFSAPLSFGTGSGLGPIVDEMQRYEKPVVAAIQGMALGGGLELSLGCHYRIAHAEARIGFPEVTLGILPGARGTQLLPRLIGVPAALDLITSGRHITAGEALKLGILDKVVNSAPVEEAIKFAQKILNQPLEPRRILNRPVSSLPNMDAIFGEAVEKMRRQHPGQLAPETCVRSVQASVQYPYEGGIMKERELFLNLQHSGQAKALQYAFFAERSAPKWSTPSGASWKTAAARPVSSVGVLGLGTMGRGIAISFARVGIPVIAVESDPKQLETAQKLITSILEKEASKSRQQCGQQRSGPKPRFSSSMKDLASVDLVVEAVFEDMNLKKRVFAELSAVCKPEAFLCTNTSALDVDEIATSTNRPQQVIGTHFFSPAHVMKLLEVIPSRHSSPTTIATVMDLAKKIKKVAVVVGNCYGFVGNRMLRSYYEQTNFLLEDGSKPEDIDQALEEFGFRMGPFRVSDLAGLDVGWKIRKGQGLTGPSLQGTAPARKRGNARYSPIADMLCELGRFGQKTGQGWYKYDKPLGRIHKPDPWLSKFLSEYRETHHIKPRVIGRDEILERCLYALINEAFRILGEGIAASPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYQQNPDIPHLEPCNYLKKLASQGNPPLKEWQSLAGLPSSKL
What is the function of this protein?
Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.  Catalyzes two of the four reactions of the long chain fatty acids peroxisomal beta-oxidation pathway (By similarity).  Can also use branched-chain fatty acids such as 2-methyl-2E-butenoyl-CoA as a substrate, which is hydrated into (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA (By similarity).  Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species.  Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity).  Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity).  Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (By similarity).
What are the official names of this protein?
Peroxisomal bifunctional enzyme, PBE, PBFE, Multifunctional enzyme 1, MFE1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RL27_MYCTU
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRYGGQVVKAGEILVRQRGTKFHPGVNVGRGGDDTLFAKTAGAVEFGIKRGRKTVSIVGSTTA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL3_CANAL
Sequence: MSHRKYEAPRHGSLGFLPRKRAAKQRGRVKSFPKDVKSKPVALTAFLGYKAGMTTIVRDLDRPGSKMHKREVVEAATVVDTPPMVVVGVVGYVETPRGLRSLTTVWAEHLSEEVRRRFYKNWYKSKKKAFTKYSGKYATDAKQVETELARIKKYASVVRVLAHTQIKKTPLSQKKAHLAEIQINGGSVSDKVDWAKEHFEKEVSVDSVFEQDEMIDVIAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPANVNWTVARAGQNGYHHRTSINHKVYRVGKGTDEANGATEFDRTKKTINPMGGFVRYGNVNNDFVLLKGSIPGVKKRVVTLRKSLYVDTSRRAVEKVNLKWIDTASRFGKGRFQTPAEKHAFMGTLKKDLEN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).  RPL3 plays a role in coordinating processes of accommodating the aminoacyl-tRNA in the PTC (By similarity).
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YR47_CAEEL
Sequence: MDICDISASQLATSPPPRTAIDFNSSIEESPVKRVKFSPELTKSFEETLSPTVTLVLRNNEEVIFDRYLLSFYSNYFRVLFSSKFRDSNSTTHRIRLISASDLHFLLTIPKAFEQGIKPNITLQKAIELLEPAAFLQMSIALDYISDIICKNLTHENIIKIFRLALLYHTTLAVRVWRSMVRKFQTLFATNVYLSLKENELIGLLTDKHLNLKSEDETTVVVNWIKHNSPLQSDRLTQFAQRNFSRRPQPDATKYEVIRTRQPMDAIVCFGGWASRGVAQKIEVCNTRSDRWQTCNFNYDIPNIHRAYHGIEVVEDKLIVYGGFDGIKQFQTTVLFDLSTKEWRRGANMNDKRCYVTSARVNDSYGRPLVFACGGMNGVSRLKTAEMYDYRADQWTEVANMTQMRSDGAVVTIDNKIVAIGGFDGRNIHQGGEVYDPVLDLWHPLSSNMRTRRTGCTAVSIMNQVCMIIGGFNGNRRLDSAEIYDMREGLWHPEPTLQTARSNFSACQMDTCYVYVAGGFDGQTTTKESERLDLRSKMWQALPDMAEAKSALRMVTLSDHPFLDELFDIPDDTGIVTSW
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein F47D12.7.
Protein: TILS_STAAC
Sequence: MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKKPGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFRP1_CHICK
Sequence: MGVGRSEGGRRGAALGVLLALGVALLAVGSASEYDYVSYQSDLGPYPGGRFYTKPHQCVAIPADLRLCHSVGYDKMVLPNLLDHETMAEVKHQASSWVPLLNKNCHMGTQVFLCSLFAPVCLDRPVYPCRWLCEAVRDSCEPVMQFFGFFWPEMLKCDQFPQDYVCIAMTTPNATEVSRPKGTTVCPPCDNEMKSEAIVEHLCASEFALKMTIKEVKKENGDKVIIPRKRKALKLGPIRKKNLKKLVLLLKNGADCPCHQLDNLGHHFLIMGRQVKTQHLLTAIYKWDKKNKEFKKFMKKVKAPDCPTFPSVFK
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types.
What are the official names of this protein?
Secreted frizzled-related protein 1, CsFRP1, sFRP-1.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted. Note=Cell membrane or extracellular matrix-associated. Released by heparin-binding (By similarity).
Protein: FEOC_YERPP
Sequence: MASLLQLRDAIALNGSAEASQLSRQLAIPLPLVNAMLEKLTAMGKIERIELDHSGCLTGSCKSCPEGHQHCNTVIYQLKEPHAHQ
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: GSIB_SHISS
Sequence: MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGTDFNAVAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAHPATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKARELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFEDADLQ
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Binds glutathione.
What are the official names of this protein?
Glutathione-binding protein GsiB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RAX1_SCHPO
Sequence: MASAPRVSEVLTKKNLPPLSLYNFYIYIRDEENAIEFLDLFLDIMLHKFLFREHIRGLYKAGVTSTSLNTESSSTLGPHHFTRFRSASLSLEDLSTVYWPNFGPLLLEELSNEQTINSSDLLLSKDRAAYLKNLLTSNIQSLTQESTVISKEQVKMFTQIIIEKYFNPASPHEVMLPPQLVQPILDCKEHQRQDELRLFEDVETYLLNFLLKPAYYRFLNHKFKHNLNPLTCTGRFIIGYVSTFAAYWLGFCGIFLDYSRRKRVWTLLPFAFGFYNLICTWSKHDPVLALLGYSEVKPFHYEKVLQPSIRLSLNRRAIFVLSIIVLIVGANTAIFSCVPSIRL
What is the function of this protein?
May be involved in cell polarization and division.
What are the official names of this protein?
Protein rax1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.