PharMolix/UniProtQA huggingface dataset:
Protein: UPP_BACC4
Sequence: MGKLYVFDHPLIQHKITYIRDKNTGTKDFRELVDEVASLMAFEITRDLPLKDIEIETPVSKATTKVIAGKKLGLIPILRAGLGMVDGILKLIPAAKVGHVGLYRDPKTLQPVEYYVKLPTDVEERDFIVLDPMLATGGSAAEAINSLKKRGAKQIKLMCIVAAPEGVKVVQEEHPDVDIYVAALDEKLNDHGYVVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ANTR2_HUMAN
Sequence: MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA
What is the function of this protein?
(Microbial infection) Receptor for the protective antigen (PA) of B. anthracis (PubMed:12700348, PubMed:15243628, PubMed:15326297).  Binding of PA leads to heptamerization of the receptor-PA complex (PubMed:12700348, PubMed:15243628, PubMed:15326297).  Upon binding of the PA of B. anthracis, the complex moves to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway (PubMed:12551953, PubMed:15337774).  In the endosomal membrane, at pH under 7, the complex then rearranges and forms a pore allowing the other components of anthrax toxin to escape to the cytoplasm (PubMed:12551953, PubMed:15337774).
What are the official names of this protein?
Anthrax toxin receptor 2, Capillary morphogenesis gene 2 protein, CMG-2.
What is the protein family that this protein belongs to?
Belongs to the ATR family.
Protein: PGK_BORBU
Sequence: MSIKTVKDFSSFAGKRALVRCDFNVPLKEGSISDDTRIRAALSTIEYLKERGARIVLVSHLGRPDGKKNPKYSLKPVANRLSELLGQDVKMLSDCIGSEVVNSTLQMKDGDVVLLENVRFYAEEEKNDKNFAKKLSENGDVFVNDAFGAAHRAHASTVGVADYLPSVGGFLMEKEDKFLGGILKNPERPFVSIIGGSKVSSKIAVLESLLSKSNVVVIGGGMAYTFLHSEGYSIGKSLLEDEYIGIASSFLKKAKELGVKVILPLDHIVADDFNKNSIPEYIDSFNIPENKIGMDIGANTLKEIENVVKTAKTIIWNGPLGVFEFDSFSKGTAKVAEMVASCSGLTVVGGGDSVAAVNKFNLSDKITHVSTGGGASLEYLEGRILPGIKVLEN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: N4B3A_XENLA
Sequence: MAAAQTFNSNCDPGNFHKLQSFPSESVTYTCKMGSVSSLIDKQDFPHDGFNLDFKPFPEPNCKRGLHQKELLSYLNITKKEVKSNKKFHSGLGFRREHSVEGGENDYPVFYHKDHRGTEFSKSSLPERGHLDKSRFGPSALRSNVKAFMSIQSLYQSGNKLSKSNGSLNTMSCVSSPPCRGPLQPSNSHSNNQSESGNDEEDDSLSDSRQNSINSLNSYSPGFSVARGQISASLGHINHIGGSLDQASRGTRDTMAGEKGTLSCRSMATLSRLQCSGEPPPPYEYSQSVEDVARQLEERLHEKGMEARQLRRNASDNDDPFTKVFEDKRRLWMEELDELKQMYMSKLQQISQQALRSQRALQLQLYKVQQEKKRLQEELNSLRGESEELRQKQSQSDNSGPKLEDSKWEISQKAGEISLLKQQLRDSQAEINQKLGEVVSLKSQLREAKVLVKEKEKESAELSTRLQALENAKSQAPVDLPRDNSDTIDLERLRAELMLERRQNEAQMLTFETERKVWKEEKDKVLRYQKEIQSSYREMYHRNQVLERQVLELRQGVGQSPSSPAIWMDTVET
What is the function of this protein?
Plays a role in axon and dendrite arborization during cranial nerve development (PubMed:24044555).  Also important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage (PubMed:28104388).
What are the official names of this protein?
NEDD4-binding protein 3-A.
What is the protein family that this protein belongs to?
Belongs to the N4BP3 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cell projection, axon. Cell projection, dendrite. Note=In developing neurons, accumulates in early growth cones and at branching points of axons and dendrites.
Protein: NO75_PEA
Sequence: PPHEKPPHENTPPEYQPPHEKPPHEHPPPEYQPPHEKPPHEKPSPKYQPPHEHSPPEYQPPHEKPPHENPPPVYKPPYENSPPPHVYHRPLFQAPPPVKPSRPFGPFPAFKN
What is the function of this protein?
Involved in early stages of root nodule development.
What are the official names of this protein?
Early nodulin-75, N-75, NGM-75.
What is the protein family that this protein belongs to?
Belongs to the nodulin 75 family.
Protein: GRIK2_XENLA
Sequence: MCAGTMKIISPSLTNSFFRCTLRFVACLFWIGYSQGTTHVLRFGGIFESVESGPSGAEELAFRFAVNTINRNRTLLPNTTITYDTQRINLYDSFEASRKACEQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTIAYDDSTGLIRLQELIKAPSRYNLRLKIRQLPIDTKDAKPLLKEMKRGKEFHVIFDCSHDMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNIENSQVLSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVASVAVQQFPQMTVSSLQCNRHKPWRFGARFINLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPTSGLNMTDNQKGKPANITDSLSNRSLIVTTILEEPYVMFKKSDKPLYGKARFEGYCIDLLEKLSRILGFEYEVRLVEDGKYGAKDDSTQQWNGMVRELMDHKADLAVAPLAITYVREQVIDFTKPFMTLGIGILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVQDGATMTFFKKSRIPTYEKMWAFMNSRSQSVLVKNNEEGIQRALTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGVLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQPPVIVKTEEVINMHTFNDRRLPGKETMA
What is the function of this protein?
Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor conferring sensitivity to cold temperatures (By similarity).  Functions in dorsal root ganglion neurons (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 2, GluK2, Glutamate receptor 6, GluR-6, GluR6.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: DEFB1_ALLPU
Sequence: MRTSYLLLFTLCLLLSEMASGDNFLTGLGHRSDHYNCVRSGGQCLYSACPIYTKIQGTCYHGKAKCCK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Beta-defensin 1, BD-1, Defensin, beta 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: RL27_MYCPN
Sequence: MNNKYFLTKIDLQFFASKKGVGSTKNGRDSHAKRLGAKKADGQMIRTGQIIYRQRGTRVYPGVNVGLGSDDTLFALSDGLVKYQKFGPKQGKTRVSVVKHKLDA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL14_PROMT
Sequence: MIQQETFLTVADNSGAKRLQCIRVLGSNRRYAHVGDVIVASVKDAMPNMGVKKSDVVKAVVVRTRATMRRETGNSIRFDDNAAVLINDDQNPRGTRVFGPVARELRERNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RLMH_TOLAT
Sequence: MKIQLIAVGTKMPDWVTTGFNEYQRRFPKDMPLELLEIPAGKRGKNADIARILEKEGEQALAAVGKSSRIVTLDLPGKNWTTPQLAQQLESWKQDGRDVALLIGGPEGLSPACKAAAEQSWCLSALTMPHPLVRIVVAESLYRAWSLTTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPOA_MOUSE
Sequence: MPFPVTTQGSQQTQPPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKESPDREEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQKRKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAASVTSIQASEVSVPQANSSESPGGPSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPSPRPSGNTATKVPNPIVGVKRTSSPNKEESPKKTKTEEDETSEDANCLALSGHDKTETKEQVDLETSAVQSETVPASASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.  Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.  May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
What are the official names of this protein?
Poly(A) polymerase alpha, PAP-alpha, Polynucleotide adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2707_BURCJ
Sequence: MPSFDVVSEANMIEVKNAIEQSNKEISTRFDFKGSDARVEQKERELTLFADDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKIGGDKVKQIVTVKKGVTGDLAKKIVRLVKDSKIKVQASIQGDAVRISGTKRDDLQSTIAMLRKDVTDTPLDFNNFRD
What are the official names of this protein?
UPF0234 protein BceJ2315_27070.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: MNHF1_STAAC
Sequence: MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_ADICA
Sequence: MRKNEMSTSKQAIQWKCLESKIESKRLHYGRFLVSPFKRGQASTVGIAMRRALLQEIEGTSITCARFCGVVHEYSTITGLQETIHDVLVNLKEIVLRGDSKEDIQEAFLSVTGPKEVTAGDLSLPPGVEAIDNSQYIATITQPISLTIELEIEKDCGYRIENLAKSGKGQFPIDAVFMPVRNVNYSIHLFGSGRATQEILFIEIWTNGSLTPHEALRKASEKLMDLLTTFLYVRGGDVSLFENGEDSLDLTKSPSLQPQFGDTNNLEERVLENRFIDQLELPARAFNCLKRAEIYTIADLLNYSREDLSKLKNFGRKSVDQVSEALWDRFAKELPDKKIVLNRRK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDKB_RAT
Sequence: MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFKPEELIDYKSCAHDWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).  Negatively regulates Rho activity by interacting with AKAP13/LBC.  Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically.  Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter.  Does not bind to duplex NHE III(1).  Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity.  Binds both folded and unfolded G4 with similar low nanomolar affinities.  Stabilizes folded G4s regardless of whether they are prefolded or not.  Exhibits histidine protein kinase activity (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B, Histidine protein kinase NDKB, P18.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Nucleus. Note=Colocalizes with ITGB1 and ITGB1BP1 at the edge or peripheral ruffles and lamellipodia during the early stages of cell spreading on fibronectin or collagen but not on vitronectin or laminin substrates.
Protein: DNAA_LEPCP
Sequence: MHTDLWERGCERLAAELPEQQFNTWIRPLPPADVTLAGDGVLVGLRVPNRFKLDWIRAQYGSRIEATLSELAGKPVRLELSLLPRDAVARAQGMAAAPAAQAGAAPQPTQSPMAIGAALHAAATARHDPQSVVPTPGGSANGRAAPRVGEPGGPVGTSTLPVAPTLSPAVSRGRLNPALTFDTLVPGRANQMARTAALHVVGAPGHMYNPLFIYGGVGLGKTHLIHAVGNALIRDNPDARVLYLHAEQFISDVVRNYQRKTFDELKAKYHSLDLLLIDDVQFFAGKDRTQEEFFNAFEALLAKRAHIIMTSDTYPKGLVDIDERLTSRFDAGLTVAIEPPELEMRVAILMKKSDAEGSRMPEDVAFFVAKNVRANVRELEGALRKVLAYSRFSHKEISINLAREALKDLLSIQNRQVSVENIQKTVADFYKIKIADMYSKKRPASIARPRQIAMYLAKEMTQKSLPEIGELFGGRDHTTVLHAVRKIGGERQKNTELNQQLHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_SHIFL
Sequence: MKPLSSPLQQYWQTVVERLPELLAEESLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQPPQADEWQHYSVWLQEALSNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPLLQSRSLLPTLSAIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTMIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWGQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRNRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVSEDCFTAERDLVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RNH2_CENSY
Sequence: MLVCGVDEAGRGSLVGPLVIAGVAIKRNRMRELKSMGVRDSKKLTRKARESLYPEIVNMADSYHISRVPPGVVDRSVGRHMLNDLEARYMARVITRLGHGTTYVDSCDVNPRRFGGRVSEMSGRTVRSYHRADDRFVIVSAASILAKVARDRSIERLRKSHDVGSGYPSDRRTVGFVRGYYNKNGAMPPFVRRSWRPARLIEAGG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LEPBL
Sequence: MSNLTARVIPCLDIKDGRVVKGVNFVDLVDAGDPVESAGIYEENLADELCFLDITASSDRREILLHLVERIAEKIFIPFTVGGGIRTVADVKAVLEKGADKISINTAAFQNPELLTHSSEIYGSQCIVCAIDVKFQKERDRYEIFLHGGRTETGREALDWAREAVGRGAGEILLTSMDRDGTRNGFDINLLKSFSSSLEIPIIASGGAGNPEHMVEAILRGKADAVLAASIFHFGEYSIRETKRAMQEMGISVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_HERAR
Sequence: MSLALSDVKRLSMLAQIDLTDAQSAQTLDKLNGIFALVEQLSAVDTTGVEPLNHPIAALLPDLSLRLRDDVVSEPNRRDDYQQVAPATQDGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PGK_BACC7
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQVVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELDVLGKALSNPDRPFTAIIGGAKVKDKIGVIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIVNIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFSQGTKAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCN_CHICK
Sequence: MPGMISKNPDLEFDSLQPCFYPDEDDFYLCGPDSAPPGEDIWKKFELLPTPPLSPSRAGLQEPPPGGGSIAVGRGGPGECRPVDPLDWASELLLLPPEAELWGSTDGADFFETGLGASNNLNSIIIQDCMWSAFSAREKLERAVSEKLQSKPPAAAPPPPPPVVPTAACRRREQPQRGPGRAELGGSVPECVDPAVVFPFPVNKREAAVPSGGETPRGGRRPGPAGESRASSSSGDDTLSDSDDEDEEEEDDEEEIDVVTVEKRRSSSNKAVTTLTITVRPKNTTFPSVRTQQNELILKRCAPIHQQHNYAAPSPYMESEDVPPQKKLKAEVPRPVKPMIQPKSKSSSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEQKLLLEKEKLQARQQQLLKKIEYKRTC
What are the official names of this protein?
N-myc proto-oncogene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: AB8G_ARATH
Sequence: MEIPPSPPPETAAYTLTTSSISYTIPKTSLSLLRFPATEPPSFILRNITLTAHPTEILAVVGPSGAGKSTLLDILASKTSPTSGSILLNSIPINPSSYRKISSYVPQHDSFFPLLTVSETFSFAACLLLPNPSIVSETVTSLLSELNLTHLSHTRLAQGLSGGERRRVSIGLSLLHDPCFLLLDEPTSGLDSKSAFDVIHILKSIAVSRQRTVILSIHQPSFKILSIIDRLLLLSKGTVVYHGRLDSLEGFLLFKGFTVPPQLNSLEYAMEILQELRESDGNTDATALPSIENRKQREKQSIVRYRKSRITEISLLARRFWKIIYRTRQLLLTNALEALVVGLVLGTIYINIGIGKAGIEKRFGMFAFTLTFLLSSTTETLPIFINERPILLRETSSGIYRLSSHILANTLVFLPYLFVISIIYSVSVYFLIGLCPTWQAFGYFVLVIWIILLMANSFVLFLSSLAPNYITGTSLVTILLAAFFLFSGYFISKESLPKYWLFMYFFSMYKYALDALLINEYSCLASKCLVWLEEAQTKICMVTGGDVLKKKGLHEKQRWFNVYVLLGFFVLYRVLCFLALLRRVSGSKR
What are the official names of this protein?
ABC transporter G family member 8, ABC transporter ABCG.8, AtABCG8, Probable white-brown complex homolog protein 8, AtWBC8.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MOAC_SALPK
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PGPA_HAEIN
Sequence: MTENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFTALCFLLGCYLCQKTTADMGVHDHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFDILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQYWML
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
What are the official names of this protein?
Phosphatidylglycerophosphatase A, Phosphatidylglycerolphosphate phosphatase A, PGP phosphatase A.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU5M_LEMCA
Sequence: MNLLSSFTLVTLIILTLPIIMNVTNMYKNYPYAPYVKSSIACAFITSLIPTMLFISSGQETIISNWHWMTIQTLKLSISFKLDYFSMLFMPVALFVTWSIMEFSMWYMHSDPNMNQFFKYLLMFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMAWFLMYSNTWEFQQMFMLNYHPDMIPLIGLLLAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLMENNKTIQTLMLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTMGINQPHLAFLHICNHAFFKAMLFMCSGSIIHNLNDEQDIRKMGGLFKSMPFTSSSLMIGSLALTGMPFLTGFYSKDLIIESVNTSNTNAWALTITLIATSMTAIYSIRIIFYALLGQPRFTTSTPINENNPLLINSIKRLALGSILAGFFLTNNILPMNVPQMTMPLYLKLTALMVTITGFALAMELNLMTNNLKFKLPSDIYKFSNSLGFYPMTMHRLIPSHNLIMSQNTASLLLDLIWMEKTMPKNLSQLQMTSSTAISNQMGLVKFYFLSFLMSLLFTLLLII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ECFT_CLOK5
Sequence: MIKDITIGQYVPGDSFIHKLDPRVKILISLIYIVDLFIVNSFKGYIFIVVFTLISILVSKVQFTYIYKGLKPIFILVLITAVLNIFMTGGANPPLFKWKFLVVYREGLIMAAFMALRLVFLIIGTSLLTLTTSPIELTDGIEKLLKPVSKIGVPSHELAMMMTIALRFIPTLMDETDKIMKAQIARGADLESGNLIQKAKNLVPILVPLFISSFRRADELAMAMEARCYRGGDGRTRMKELKLSNRDFIASLCALVLVCISILSRIWWGK
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.