PharMolix/UniProtQA huggingface dataset:
Protein: PYVC_ASPV1
Sequence: MEQASATTTVDVLIVGGGIGGLTLAGICKKLGITYKVLERSAEITPVGAGISLAPNCLRILEQLGHLDFIRRKGQPLRKIQIFRNSTPWSLVDYDWVQEKFGYSVYSIERHSMHQVLYQGAGPEHVLLDAEVVDIEDVPTAPSVQVRLADGRQLAGQLVVGADGIRSATRRILAATQGLEGANTIRFTGRTHMTGYTHPLQHLGPADLGVATWVFYDDSILTSWPCIDNRQWFVGVKSSELKNPTRSSWKNATQAIINDVYGDRFHPFGEHHRVRDVVNLAERVTASDVFEETTFPAMACGRVALVGDSAHSMTSFIGQGACQAIEDAGELANALHAYFASQSPSPQMLRERLEEYRHRREARARYVFSFSSLFAQLHTGRLWSPMGPLLRWVAFVCAPMWCWHRALTPLYGYQPVVHALVDAPHAN
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of pyranoviolin A, a pyranonigrin analog with a C-3 methoxy group (PubMed:33117309).  Initially, the PKS portion of pyvA synthesizes C-10 carbon chain from 5 molecules of malonyl-CoA, which is then condensed with the thiolation (T) domain-bound glycine activated by the adenylation (A) domain (PubMed:33117309).  The subsequent chain release by Dieckmann condensation (DKC) could be catalyzed by the TE domain present at the C-terminus of pyvA and/or the alpha/beta hydrolase pyvD, installing the tetramic acid moiety (Probable).  The FAD-dependent monooxygenase pyvC next epoxidizes one of the olefins of the polyketide part, and the epoxide ring-opening induces the dihydro-gamma-pyrone ring formation (Probable).  The cytochrome P450 monooxygeanse pyvB would be responsible for the 2 consecutive reactions, in which the dihydro-gamma-pyrone is oxidized to gamma-pyrone and C-7 is hydroxylated to yield pyranonigrin F (Probable).  Finally, the O-methyltransferase pyvH methylates the C-3 hydroxy group to complete the biosynthesis (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase pyvC, Pyranoviolin A biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: VITM_MANSE
Sequence: MLRTTVVLLTLAAIAFAAPTSDDIYNNVVIGDIDGAVAKSKELQKQGKGDIITEAVNRLIRDSQRNTMEYAYQLWSLEARDIVKERFPIQFRMMLGEHSIKLINKRDNLAMKLGVATDNSGDRIAYGAADDKTSDRVAWKFVPLSEDKRVYFKILNVQRGQYLKLGVETDSDGEHMAYASSGADTFRHQWYLQPAKADGNLVFFIVNREYNHALKLGRSVDSMGDRQVWGHNGNVIGNPELFGWSVVAF
What is the function of this protein?
Small vitellogenic protein found in females.  It is synthesized in the fat body, secreted into the hemolymph, and taken up by developing oocytes.
What are the official names of this protein?
Microvitellogenin.
Protein: COBS_LISMF
Sequence: MKTLILLIQFFTRIPLPVQINMDEINLKKGSALLPFVGVIIGAWNWLIFTLVALLMPLPVAIIAGLFAEIIITGGFHVDALADTADGLFSSRKRERMLEIMKDSRVGANGVIAICFYFLFYGSLFLSVPDTQQIGWLFFVLPIVAKGVTMLLFAKMTYAGSKEGLGSIFLGVPWWPVVIAQVIVLVALGAFFSYIGVIAYAGVILFTIIYRAFVYKRIGGMNGDTLGAGGQMGQLICLFCLVLLWGLI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPEP2_HUMAN
Sequence: MQPSGLEGPGTFGRWPLLSLLLLLLLLQPVTCAYTTPGPPRALTTLGAPRAHTMPGTYAPSTTLSSPSTQGLQEQARALMRDFPLVDGHNDLPLVLRQVYQKGLQDVNLRNFSYGQTSLDRLRDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVTSAKALNDTQKLACLIGVEGGHSLDNSLSILRTFYMLGVRYLTLTHTCNTPWAESSAKGVHSFYNNISGLTDFGEKVVAEMNRLGMMVDLSHVSDAVARRALEVSQAPVIFSHSAARGVCNSARNVPDDILQLLKKNGGVVMVSLSMGVIQCNPSANVSTVADHFDHIKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDEQLSSSCHSDLSRLRQRQSLTSGQELTEIPIHWTAKLPAKWSVSESSPHMAPVLAVVATFPVLILWL
What is the function of this protein?
Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappaB inflammatory signaling pathway.
What are the official names of this protein?
Dipeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor, GPI-anchor.
Protein: O163_CONTE
Sequence: MKLTCVVIVAVLFLTAWTFVTAVPHSSNALENLYLKAHHEMNNPEASELNKRCYDGGTSCDSGIQCCSGWCIFVCF
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like TxO3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAC_PROMM
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGHKSGQIAASPRTEDCVGCKRCETACPTHFLSIRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL31_THEAC
Sequence: MADETVAQEVIINVPLRDAKASSRKRRADTAVSILRNFVSKKMKIDKGKIWIDPKVSEKIWERGREHIPSKMSVKVIKLEEGTTEIIMP
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: GRCA_SALPB
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: ACEA_MAGOY
Sequence: MASKNMVNPAVEPSMEDDLFAREVAEVKQWWSDPRWRYTKRPFTAEQIVSKRGNLKIEYPSNAQSKKLWKILEGRFQKRDASYTYGCLEPTMVTQMAKYLDTVYVSGWQSSSTASSSDEPGPDLADYPYTTVPNKVSHLFMAQLFHDRKQRHERLSAPKSERSKLQNIDYLRPIIADADTGHGGLTAVMKLTKLFIEKGAAGIHIEDQAPGTKKCGHMAGKVLVPINEHINRLVAIRAQADIMGVDLLAIARTDAEAATLITTSIDPRDHAFILGCTNPSLQPLADLMNTAEQSGKTGDQLQAIEDEWMAKANLKRFDDAVVDVINSSSSIRNPKDVAAKYLQAAKGKSNREARAIASSLGVPEIFFDWDSPRTREGYFRIKGGCDCAINRAIAYAPYADAIWMESKLPDYEQAKEFAEGVHAVYPEQKLAYNLSPSFNWKTAMPRDEQETYIRRLAGLGYCWQFITLAGLHTTALISDRFARAYSEVGMRAYGELVQEPEMELGVDVVKHQKWSGATYVDELQKMVTGGVSSTAAMGKGVTEDQFH
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: PRP5_MAGO7
Sequence: METEQQQRKDSVASAGSTRQLLAQMDVKATGSPSAMTSPGAASPATAQSAEDASPAVPYGGKFDPKAIAKKASARHQSPTVLGALQGRAAEKTAVSIAAPAKGSAASSLPQGKPISGFGFGKASNDDKVPTKRKLNLDDEEISKRKLAKLPDLSLETTDDAPYVNQDDDEDSDGDNFAGTEEEAAAAARAAHERREERILQQSMAMETDEANPAAEGQVNGSEPAVSSANAPEEAQAKPQTDSMDVDTKEDDDEVDPLDAFMADLTEPSFGPASKPVKTLSSAKVLPTPEAYFSDDDEFGASTKEGVDAKAIMAMAAKRKKKEIPTIDYSKLDIVPVRKNFWVEPYELSEMTEAEVAELRLELDGIKVSGKDVPKPVQKWSLCGLTRPILDVIAKLEYDKPTAIQMQALPVIMSGRDVVGVAKTGSGKTMAFLLPMFRHIKDQEPVKDNEGPIGLILTPTRELAVQIFRDCKPFLKTLGLRAVCAYGGPPIKDQIADLKRGAEIVVATTGRMIDLLAANQGRVVSLRRTTYIVLDEADRMFDMGFEPQVMKIFANVRPDRQTVLFSATMPKIMDALVKKVLKNPVEIEVGGKSVVASEITQIVEIRDEKSKFNRLLELLGELYKDDDDVRSLIFVERQEKADELLRELLRKGYGCMSLHGGKDQVDRDSTISDFKSGVCPVMIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFVTEEQENCAIGIAKALEQSGQPVPEKLIEMRKAFREKVKAGKAKDQSGFGGKGLEKLDKEREAARNRERKTHKAEGEEDDAEDDKKTTKNDEKTDKASSAILGAASAIVSRDAAKAEAEAKAAEGGSTPTAAATPAAGGKGGALDKAASAINEINARLARAGQLRPGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGNYYPPGKDPPAGADPKLYILIEGDTELVVGNALSELTRLLKEGTMAAADAESRAPASGRYTIT
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHI5_ORYSJ
Sequence: MANSPTPTMLAFLALGLALLLSATGQASAQNCGCQSNMCCSKWGYCGTGKDYCGDGCRSGPCYGGGGGGGGGGGGGGGGGGGSGVSVESVVTEAFFNGIKNQAPNGCAGKNFYTRQSFLNAAHSYSGFARDRTNDDSKREIAAFFAHVTHETGHMCYINEINGASMDYCDKNNKQWPCQPGKKYYGRGPLQISWNYNYGPAGQNIGFDGLRDPDRVAQDPTISFKTALWFWMNNVHQVMLQGFGATIRAINGALECNGKNPGAVNARVNYYKDYCRQFGVDPGGNLYC
What is the function of this protein?
May function in reproductive organs during embryogenesis and seed maturation.
What are the official names of this protein?
Chitinase 5, Class IV chitinase a, OsChia4a, Pathogenesis related (PR)-3 chitinase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class IV subfamily.
Protein: PGK_LEPBJ
Sequence: MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQTNPEFSLAPVVEVFKGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFHKEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIAHLLPAYAGLLMHKEIVELSALLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEKDFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMGVFEMDKFAGGTMAIAKAISKSKAKTVVGGGDSIAAINKAKVADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_BURP1
Sequence: MAKEKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSAKFGGEAKKYDEIDAAPEEKARGITINTAHIEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDKGELGEVAIMNLADALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGVIKVGEEIEIVGIKATAKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVERGQVLAKPGSITPHTHFTAEVYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPKDKEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_CYTH3
Sequence: MQLTNRSKVVVDKKMTFMERIYIPSIVSGMMITLSHLFKKKATIQYPEVQREFAFVYRGKHILKRDEQGRENCTACGLCAVSCPAEAITIIADERKKGEEHLYKEEKYASLYEINMLRCIFCGLCEEACPKDAVYLTEELVPAQYNRKDFIYGKDKLVQPLGTSAHPKTYKPYKK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPD_STRP4
Sequence: MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HRCA_MYCGE
Sequence: MKNLTPRQAQILKAIINEYIAYAIPVGSKLLTKKYFKNLSGGTLRNEMAALEKKGFLKKNHISSGRVPSQIGYQYYVKVLNVSNTTNDLKTRLRSVILQQHKTIDEVIELGVKFINEIINLPVVLTNFSSDEVLKKIDLIILDKSFALFLLVSASGKVFKKTISYANQRQFEDIVICVRIFNDRIIDTRFSEINNQLEVLKEIIRTKVHEYQYVIDEILFKLFDLDQIEANKKIYGIQYLAKQPEFANQEKLTKILNLLEDTSVWQQMAFINQTNQKTNIVFGDQLGFKEISVASTLINTTSEAKHQLAIVGPTRMDYQKIKALLTTLKEEIEKYDKKIHNQT
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RCF1_EMENI
Sequence: MSEPLPSSFDGHEQFQEETPLQKFGRRFKEEPWVPAVGLLGCAATCYALWRAYRSMKAGDSVEMNRMFRARIYAQGLTLLTVVAGGLYYRTERTQRREFEQALELRKGQEKRDAWLRELEIRDKEDKEWRERHAAIEAAAKQAGNKPVLAEQDAARSALEPSEQKYYGVLDAVRDLVSRRE
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ARH_HUMAN
Sequence: MDALKSAGRALIRSPSLAKQSWGGGGRHRKLPENWTDTRETLLEGMLFSLKYLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVTLKVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSKEEKEKRDKASQEGGDVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVSANTTNMDEVPRPQALSGSSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLTAQDMHYAQCLSPVDWDKPDSSGTEQDDLFSF
What is the function of this protein?
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts).  May be required for LDL binding and internalization but not for receptor clustering in coated pits.  May facilitate the endocytosis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.  May also be involved in the internalization of other LDLR family members.  Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.  Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression (By similarity).
What are the official names of this protein?
Low density lipoprotein receptor adapter protein 1, Autosomal recessive hypercholesterolemia protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTE_ECOBW
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: CHMU_MYCTO
Sequence: MRPEPPHHENAELAAMNLEMLESQPVPEIDTLREEIDRLDAEILALVKRRAEVSKAIGKARMASGGTRLVHSREMKVIERYSELGPDGKDLAILLLRLGRGRLGH
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate.  Probably involved in the aromatic amino acid biosynthesis.
What are the official names of this protein?
Intracellular chorismate mutase, CM.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_BORPE
Sequence: MEQIPFVSSAPNTLGIELELQLVDPRSFDLAAASDELLAQLANHPIADRVKPEITRSMIELNSSVHEHPAGLLAEMREMRDVLCEAADAVGVGVTGGGAHPFMRWQDRAISDTPRFQYLAEMYGYLARQFTVFGQHIHLGVPSGDAAVRMVRGLSPYVPHFIALSAASPYCEGVDTLFSCCRLNAVNSFPLAGHMPADVTDWYRFEAHLAQLCASGLAESIKDLYWDIRPKPEYGTVEIRVCDTPLTVERACQLAAFAQALAVQVARDPEPSQQAWLAYRSNHFQACRFGLHGSYVTPDGQRVRLVDHLRALFERLAPVAEELGTGDMLQTLRDEILRNGNDARWLRGQFLKVRELPLVVESMAQNWRGQGVQDTPPSAVRRRIRATSEPVGGVCALSTPQGDPLPGWAERLH
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: HCAB_ECO57
Sequence: MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLGYLLGAKACAPALIAGEGSMIFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL
What is the function of this protein?
Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively.
What are the official names of this protein?
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase, 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase, CI-dihydrodiol dehydrogenase, Cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, Cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, PP-dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TX22E_PLETR
Sequence: ALKCQGWVDYCNGNVECCNECVMY
What is the function of this protein?
Potent toxin that may paralyze and/or kill insect pests such as H. virescens (lepidoptera), S. exigua (beet armyworm) and M. sexta (tobacco hornworm).
What are the official names of this protein?
U1-plectoxin-Pt1e, U1-PLTX-Pt1e, Plectoxin XIII, PLT-XIII, PLTXIII, Plectoxin-13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 02 (plectoxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: P47K_PSECL
Sequence: MIEGAQAGRLPVTVLSGFLGAGKTTLLNAILRNRQGLRVAVIVNDMSEVNLDAESVQRDVSLHRGRDELIEMSNGCICCTLRADLLEQISDLARQQRFDYLLIESTGISEPMPVAETFAFLDTEGFSLSELARLDTLVTVVDGSQFQALLESTDTVARADTEAHTSTRHLADLLIEQVEYANVILVNKRDLIDEPGYQAVHAILAGLNPSARIMPMAHGNVALSSLLDTHLFDLPSLAASPGWMRKMEATDTPASESDTYGVTSWVYRERAPFHPQRLLEFLQKPWHNGRLLRSKGYFWLASRHLEIGLLAQSGKQFQWDYVGRWWNFIEPSQWPRDEYRLQGIMAKWDSVVGDCRQELVFIGQGLDTRVLQRELDHCLLSAQEIAAGPLAWQALPAATAFDTEALSARPTPPMAVQPT
What is the function of this protein?
Zinc chaperone that directly transfers zinc cofactor to target proteins, thereby activating them.  Zinc is transferred from the CXCC motif in the GTPase domain to the zinc binding site in target proteins in a process requiring GTP hydrolysis.
What are the official names of this protein?
Zinc chaperone P47K, 47 kDa protein, P47K.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Protein: SCX37_TITSE
Sequence: MAGEWACLLVSLVLLWGAAGSRDGFLLDRNFCRIKCSFLGSNSMCADRCTVLGASAGHCNNYACFCTDLRDRVKIWGDSVRCRKP
What is the function of this protein?
Putative sodium channel toxin.
What are the official names of this protein?
Putative sodium channel toxin Ts37, Tityustoxin-37.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTL_ARATH
Sequence: MKKPSKKSEIEFCTVCRFHHDQGSRHKYFPRHKSSLSSLLDRFRSKIADVRFFLKNPSVLRPQEQSQNRVWCVFCDEDIVELGSSFACSKAINHFASSDHLKNIKQFLSKNGPAMDCIDEFRISEADVAKWEKKCQSFGNEDASFEGSCGQLSGTSNDIHTKLAFETMDRIKKVPAHHINSYKSNDVMPLQYNTNEYQISLSEIPGVIHNGSYLNMDDSQFPLCDESGNGFGEHSIPCRSKDYSGNGNYCTQENYQVSQDKKQIDGSYNPPGVVGMTSISSSHSTDAGGNVHSGAPPPWLDANDGDFSSVQLNQSDVARFQAKVPGKNRKLNPNRVGAAWAERRKIEIEMEKSGHVTKSNIDPDWLPNFGRVWQSGTRKESRKEFEKEKRKLVKTESISTESEPVKIQPYISKRARRESGE
What is the function of this protein?
Key regulator for endosperm and embryo nuclear divisions.
What are the official names of this protein?
TITAN-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_METS4
Sequence: MPQAVAGPEIERLIQLLARMPGLGPRSARRAALQLIKKRDTLLGPLAEAMRVASERIVTCRECGNVDTCDPCTICRDHGRDPSMLVVVEDVSDLWALERSGAVTARYHVLGGILSALDGIRPENLNLARLVERASVPEMREIILALSATVDGQTTAHYVTELLAHLPVKVTKLAHGVPVGGELDYLDEGTLSAAIRQRTAF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL23_AQUPY
Sequence: MSQRKPWEILIRPIITEKSNRLMEDYNKYTFEVALDASKPEIKEAVEKLFNVKVKKVNTMIVKPKKKRVWERFRQYGTTKKWKKAIVTLEKGINRHPWVCSEVRCRDGC
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FOLD_BIFA0
Sequence: MAIVLDGKKVAGQIKADLASRVAGLARMGMVPGLGTVLVGDDPGSMKYVEGKHRDCEEVGIASIRRQLPATATTEDVLAVVRDLNEDPACTGYIIQLPLPAHIDSNAIIGAIDPTKDADGMHPYNLGELVLHVRGDITTPLPCTPRGVLALLDAYGIELAGRNVCVLGRGITIGRTIGLMLTRSGVNATVTLCHTGTRNIEEHIRRADVVIAAVGVAGFVQVEHVKPGAVLIDVGVSRVFDEQAGRMRIVGDVDSEAHAVAGAYSPNPGGVGPMTRAMLLANVVEQAERMAGIREDS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.