PharMolix/UniProtQA huggingface dataset:
Protein: SECA_FRATM
Sequence: MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMRTGEGKTLVATLPAYLNALTCDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYAIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNRLVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQLNIDYIVRDREIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNAKQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVPAGSMHELWDLEGLEKALKSDFMIELDLQKLYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIVTEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRREGPKVKRNDPCPCGSGKKYKQCHSKVE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL15_LIMF3
Sequence: MQLNELKPVAGSRFKRLRKGRGLSSGHGFTSGRGTKGQKAHGKTRLGFEGGQMPLYRQKPKRGFTSMDHKDFALVSLTTLNQFEDGAEVTPEVLVANGVIKNVKSGVKVLATGKLEKKLTVKANKFSASAVKAIEAAGGTTEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYFA_PHOV8
Sequence: MLAKIEQLLQEIEGLQAANAEELEALRIKYLSKKGAINELMADFRNVPAEQKKEVGMKLNELKNKAQERIASLKEAFETQDNSAAEMDLTRTAYPIELGTRHPLSIVKNEIIDIFHRLGFSIADGPEIEDDLHVFTAMNFAEDHPARDMQDTFFIEANQEDVKKNIVLRTHTSSVQARAMEHSQPPIRIICPGRVYRNEAISYRAHAFFHQVEALYIDKNVSFTDLKQVLLLFAKEMFGEDTQIRLRPSYFPFTEPSAEMDISCNICGGKGCPFCKGTGWVEILGCGMVDPNVLEANGIDSKVYSGYALGMGIERITNLKYRVNDLRLFSENDTRFLKEFEAAN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MZM1_YEAS8
Sequence: MSTRTKALNAYRHGLRATRIAFRNDAEVLLAARAKMRSGMLCPPDPKLTTEDQIQHLEDVAVFLRRNLVQGKKVDGSSTKEPRYHLNIHKDTELGDNETIADPTARVKTNLKARPFKCSDKKQ
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial, Altered inheritance of mitochondria protein 8, Found in mitochondrial proteome protein 36.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SHSL1_DANRE
Sequence: MIMNGRWSFNTLAIIFILLSTAALSAHFRVCEPYSDHKGRYHFGFHCPRLSDNKTYIFCCHHNNTAFKYCCNETEFQSVMQLNLTANSDSFAHNNYTALIGVWIYGFFVMVLLALDFLYYSAMNYELCRVYLEKWGLGGRWLKQARSQWHSTVQEGELNTGPGLSQQQQLHLHHHHHHHHPRHSLRGDTQSPTLLSFQTSTAW
What are the official names of this protein?
Protein shisa-like-1a.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PYC1_SYNY4
Sequence: MRMFRITACVPSQTRIRTQRELQNTYFTKLVPYDNWFREQQRIMKMGGKIVKVELATGRPGTNAGLA
What is the function of this protein?
Rod linker protein, associated with allophycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity).
What are the official names of this protein?
Phycobilisome 7.8 kDa linker polypeptide, allophycocyanin-associated, core, LC 7.8.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with allophycocyanin.
Protein: SCAF_EHV2
Sequence: MSSPSPSSSSSDHPSSPAPVPAPPGPVPEAAAASRASRAPVYLGGFVDVFSYPKDSRALYLNPADVGAHLPLPGPIPLNVEHLQEAHVGWTLGLHLTRYGLFCVAVITAEEFFTLLDRLCAASSVARTRADHHLPPNPTLEMLHTWLPELSLSSIHPDALPGAKGGDTPIFQHVALCAMGQRRGTVAVYGESLDWILSKFTSLSPEERGAIAEGYASPAPESLPEPHFTCSNEILMAKAIDAGFIKNRLEILKTDKGVAEVKAPTYLKASVQGLPANLDEVDSARGGEDPPTAAIATTPHPATDATTMNQQQPFAAQAPAGGCEDLISVPRSTFMTMLQTNLDTMRQTSLGQRFGQPIDAPAAPPAQLRVPPPAAPFPVHPGYYPAPYHPQVDAQAQYLPYVPLPPPGAMPFAPPPLPDFYKYGGIPAPGYSPVAHPARPGKRKRDCDEEFEGPLFPGEIHKDVQSLSKSIAALQSELKDIKNSQQFPQPLPQPQLQPQAQPQPQPAPQLYPAPPQAFYHPAAGDQGYYVRYLNPFQASGGVPCAPGPQGVGEPQAPQVTVTHNGHQAAPQAGGGATGATAANVEQRQPEGGEACGAQQQQPPQPQPQQQQQPQQQAFVEASTKPSQISQLQKIFCEELLNKT
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: Y562_KLEP3
Sequence: METLAAIGRWLSKQHVVTWCVSRDDELWCANAFYVYDQDTVAFYLLSDEHTRHGQMTGERAKVAGTVNGQPKTVALIRGVQFKGEIRRLSGDEEARMRQRYVKRFPVARMLSAPVWEIRPDEIKFTDNTLGFGKKLHWRRDAGAEQA
What are the official names of this protein?
UPF0306 protein KPK_0562.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: C91_GEMSO
Sequence: MMAKLMITVMTVFFLSLQQGADGLFERWRKNQMAASRIMGNLITARLDPPGYCTHKICYEDGECNQWCTAGCNPDTGKCDTT
What are the official names of this protein?
Turripeptide Gsg9.1.
What is the protein family that this protein belongs to?
Belongs to the Pg turripeptide superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNB2_ADE07
Sequence: MASRGGNQSSDRQREHTPERGMGSASHPPPRPDRSPSQSPPPLPPKRNTYRRVGSNSSIESQVVLVSETSRSSLSPERSNSPPPIPPKKKPRKTKHVPLQDISQDSEEEREQVQLVRVGFSYPPVRIIEKDGKRSVEKIDNNDPISKGATSIAVRNPLSLPLVSAWEKGMEVMAVLMERYRLDNDLRTSFKLMPEQHEQYKRICHQYVNEEHRGIPLTFSSMKTLTAMMGRFMQGLVHSYSEIAHNNWECTGCALWAHGCTDYEGKVKCLHGTIMIQKDHIIEMDVASENGQRAMKENPDRAKITQNRWGRNVVQLANNDARCCVNDANCATNQFSSKSCGMFYTEGIKAQEAFKQYEAFMKAVYPGITPDQARMMLIPIHCDCNHKPGCAPVMGRQTCKMTPFGMANAEDLDVATISDPTVLASVRHPALMVFQCCNPVYRNSRVQNAGPNCDFKISAPDLLGALQLTRKLWQDTFPEIPVPKLVIPEFKWQNRLQFRNVSLPAGHYDSRQNPFDF
What is the function of this protein?
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers.  Also enhances the rate of initiation.  Released from template upon second strand synthesis.  Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication.  Covers the whole ssDNA genome during synthesis.  The complementary strand synthesis induces its relese from DNA template.  May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
What are the official names of this protein?
DNA-binding protein, DBP, Early 2A protein, Early E2A DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E2A DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Accumulates in infected cells.
Protein: TRXH_PICMA
Sequence: MAEGNVFACHSTEGWRSKLQEAIDTKRLVAVDFTATWCGPCRVIGPVFVELSKKFPEIFFLKVDVDELRDVAQEWDVEAMPTFIFIKDGKAVDKVVGAKKDDLERKVAALAAAATTTEATLPAQA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes (By similarity).
What are the official names of this protein?
Thioredoxin H-type, Trx-H.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_ECO55
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
What is the function of this protein?
Negative regulator of phage lambda lysogenization.  Contributes to the degradation of the phage regulatory protein CII.  Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
What are the official names of this protein?
High frequency lysogenization protein HflD.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PLEK2_MOUSE
Sequence: MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLLYYKLEGGRRVTPPKGRIVLDGCTITCPCLEYENRPLLIKLKTRTSTEYFLEACSREERDSWAFEITGAIHAGQPGKIQQLHILKNSFKLPPHISLHRIVDKMHDTSTGIRPSPNMEQGSTYKKTFLGSSLVDWLISSNFAASRLEAVTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKVSSKEEISLSTMELSGTVVKQGYLSKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT
What is the function of this protein?
May help orchestrate cytoskeletal arrangement.  Contribute to lamellipodia formation.  Overexpression of pleckstrin 2 causes large lamellipodia and peripheral ruffle formation.
What are the official names of this protein?
Pleckstrin-2.
What are the subcellular locations of this protein?
Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: GAG_MLVAV
Sequence: MGQTVTTPLSLTLEHWEDVQRIASNQSVDVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSPSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLSEDPPPYGGQGLSSSDGDGDREEATSTSEIPAPSPIVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVDAAFPLERPDWDYTTQRGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAERIFNKRETPEEREERVRRETEEKEERRRAEEEQKEKERDRRRHREMSKLLATVVSGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10-Gag]: Virion. SUBCELLULAR LOCATION: [RNA-binding phosphoprotein p12]: Host cytoplasm. Note=Localizes to the host cytoplasm early in infection and binds to the mitotic chromosomes later on.
Protein: TI10B_XENLA
Sequence: MDPLKAQQLAAELEVEMMADMYNRMTGACHKKCVPPHYKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSLQDEELMKKMQQGVTST
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10-B.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: NUOH_RICFE
Sequence: MTELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSDKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGLVIITVLLTTGTLNLSGIIEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDFIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLSNV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLPK_STAA9
Sequence: MEKYILSIDQGTTSSRAILFNQKGEIAGVAQREFKQYFPQSGWVEHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVWQSRQTQSICSELKQQGYEQTFRDKTGLLLDPYFAGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGKAAHITDYSNASRTLMFNIHDLEWDDELLELLTVPKNMLPEVKPSSEIYGKTIDYHFYGQEVPIAGVAGDQQAALFGQACFECGDVKNTYGTGGFMLMNTGDKAVKSESGLLTTIAYGIDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSESYATRVDSTEGVYVVPAFVGLGTPYWDSEARGAIFGLTRGTEKEHFIRATLESLCYQTRDVMEAMSKDSGIDVQSLRVDGGAVKNNFIMQFQADIVNTSVERPEIQETTALGAAFLAGLAVGFWESKDDIAKNWKLEEKFDPKMDEGEREKLYRGWKKAVEATQVFKTE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AROQ_PROMT
Sequence: MDLLLINGPNLNLVGKREPSIYGSQTLEDIQAELLTLASELDAKLKFFQSNSEGEMIDCIQKSVGSIDGILINAGAYTHTSIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKALGLVCGFGANSYQLALEGIVSYLKRV
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: LIPB_ECO8A
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLR1_CANGA
Sequence: MNYLHNFKDTLFVDLLEVLNIVTIGEEHVNQLNLSGDASLSASSESSNMSFNSGSEENSQEKSVEDLEKQNCEINIHKNSDKEADTKKDPFLVTFNGEDDPLMPYNWSTNKKALIIIQTMLLTCVNYMGSSIYTPGQLEIQNEFHVGHVVGTLNLSLYVLGYGLGPIVFSPLTEISSIGRLPVYMITFFLFTMLQIGCALAPNFAGLVILRFITGVLCSPALSTGGATLGDIVSQNYLALVLGLWSIGAVAAPVLAPLLGASMVVAKDWRWIFWLLFFCCCATMLLLTFFFPETSSDTVLHRKAARIRKLTGDNRYYTEKEREEAQLPKKQFLIETLYRPFSMMITEPIVLAFDLYIALCYGAFYLFFEAFPIVFGGIYHFTLVEQGLAYFGFCVGCIFAYIILLVFSIKVAAKRFANNTFTPETTLILAMCIGWCIPLALFMFGWTAKVHWILPIISEVFFVLGCFNIFQASFSYLAICYPKYVASVFAGNGFARSSFAAAFPLFGQAMYNNLGTKNYPVAWGSSLVGFFTIGLWVIPFVLYKYGPSLRSMSKYNR
What is the function of this protein?
Multidrug transporter that confers resistance to 5-flucytosine (5-FC) and clotrimazole (PubMed:28066366).  Confers also resistance to benomyl, but not 4-nitroquinoline-N-oxide, cycloheximide, or fluconazole (PubMed:17046176).  Plays direct roles in extrusion of 5-flucytosine and clotrimazole (PubMed:28066366).
What are the official names of this protein?
Multidrug transporter FLR1, Drug:H(+) antiporter FLR1, DHA FLR1, Flucytosine exporter FLR1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURQ_SYNY3
Sequence: MTSFGIIVFPGSNCDRDIATVTAGLLDQPTRFIWHQETDLHGVDVVVLPGGFSYGDYLRCGAIARFSPIMTAIIDHANAGKRVLGICNGFQVLTEVGLLPGALIRNRDLHFICDRVTVRVESNQTVWTKGYQSQQVITLPIAHGEGRYFADGDTLKALEDNEQILFRYSNAQGELTTDSNPNGSLHNIAGITNVQGNVLGMMPHPERAADRLLKATDGLAMFIS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_UREPA
Sequence: MAKVNAFSKKIGWIELITGPMFAGKTAELIRRLHRLEYADVKYLVFKPKIDTRSIRNIQSRTGTSLPSVEVESAPEILNYIMSNSFNDETKVIGIDEVQFFDDRICEVANILAENGFVVIISGLDKNFKGEPFGPIAKLFTYADKITKLTAICNECGAEATHSLRKIDGKHADYNDDIVKIGCQEFYSAVCRHHHKVPNRPYLNSNSEEFIKFFKNKKRNKNI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_ECO45
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIIHFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_LISMO
Sequence: MEKKVEAILEFDKIKKQLTEFASSSLGEQAILELAPATDFQVVQKTQLETEEGAKIIRLRGSAPITGLTDVFAHLKRLEIGGDLNGLEIYQIGSNLRVSRQMKNFMNDLLEIGVELPILGALSDELLVLKEVEEDIAISVDESGKVLDTASEALSTIRRTLRRTEDRVREKLESYLRDRNASKMLSDAVITIRNDRYVIPVKQEYKGHYGGIVHDQSASGQTLFIEPQSVVDLNNERKALQAKEKQEIERILAEISASLAAWINEIHHNTFILGRFDFIFAKARFGKAMKAVTPHLSDAGVVHLIAARHPLLDAAKVVANDIYLGEDFTTIVITGPNTGGKTITLKTLGLLTLMAQSGLQIPAQEDSTIAVFEHVFADIGDEQSIEQSLSTFSSHMTNIVSILEKVNQKSLILYDELGAGTDPQEGAALAIAILDASHEKGASVVATTHYPELKAYGYNRVHATNASVEFNVETLSPTYKLLIGVPGRSNAFDISRRLGLSENIITEARSLVDTESADLNDMISSLEEKRNLAETEYEEARELARGADNLLKDLQKEITNYYQQKDKLIEQASEKAATIVEKAEAEAEEIIRELRTMQLNGAAGIKEHELIDAKTRLGNAKPKTINKTIPQAPKQKPHVFQEGDNVRVLSLGQKGTLLNKISDKEWNVQIGIIKMKIKTADLEYIQPEKPKKQRIITSVHSSGSPAKSELDLRGERYEDALQKVDKYLDEALLAGYPQVAIIHGKGTGALRTGVTEYLKNHRMVKSIRFGAAAEGGNGVTIVEFK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: TUAD_BACSU
Sequence: MKKIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLDQRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKSTVPVGTGKLVQSIVQKASKGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHKAAAIIEELHQPFHAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADGVGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVDKLLTVMGSVKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPEASAILGEQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFSLEEMQAAGYIYHSIGRPAVRGTEPSDKYFPGLPLEELAKDLGSVNL
What is the function of this protein?
Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase TuaD, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH, Teichuronic acid biosynthesis protein TuaD.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_ECOL6
Sequence: MSKVCIIAWVYGRVQGVGFRYTTQYEAKKLGLTGYAKNLDDGSVEVVACGDEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: CRCB_ECO24
Sequence: MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIGAFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVFVNLLGSFAMTALAFWLFSASTAH
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.