PharMolix/UniProtQA huggingface dataset:
Protein: ONCM_BOVIN
Sequence: MGAQRMQRTLLSLVLRLLLLCTVATGKCSGKYHELLLQLQRQADLMQDPSTLLDPYIHLQGLHSPVLQEHCRERPGDFPSEDALWRLSRQDFLQTLNTTLGLILRMLSALQQDLPEAAHQQAEMNVRGFGNNIHCMAQLLRGSSDPKAAEPTQPGPGPTPLPPTPPSSTFQRKLRNCGFLRGYHRFMRTAGQVLRGWGERQGRSRRHSPCRALKRGARRTQPFPEIRRLAPRGQPPGSLWGAPAR
What is the function of this protein?
Growth regulator.  Inhibits the proliferation of a number of tumor cell lines.  It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.  Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST) (By similarity).  Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
What are the official names of this protein?
Oncostatin-M, OSM.
What is the protein family that this protein belongs to?
Belongs to the LIF/OSM family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_ALKOO
Sequence: MKLHELRPAEGAVRDRKRKGRGTASGLGKTAGRGSNGQKARSGGGVRPGFEGGQMPLYRRLPKRGFTNIFANVYNEINIDRLNAFENGTVVTAELLKETGVIKKIEKDGIKILGNGNLEKSLTVQAQKFTKSAIEKIEAAGGKAEVM
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RPOC_CHLP8
Sequence: MIFSQGSSPIKGDFSKIKFSIASPESILAHSRGEVLKPETINYRTFKPERDGLMCEKIFGPTKDWECYCGKYKRVRYKGIICDRCGVEVTTKNVRRERMGHISLAVPVVHTWFFRSVPSKIGALLDLSTKELERIIYYEVYVVINPGEPGEKQGIKKFDRLTEEQYFQIITEYEDNQDLEDNDPAKFVAKMGGEAIHTLLKGLNLDEIAVNLRKVLKESGSEQKRADALKRLKVVESFRKSYEPQKRTRKKSTGLFPEEDSPELYIYEGNKPEYMVMEVVPVIPPELRPLVPLEGGRFATSDLNDLYRRVIIRNNRLKKLIDIRAPEVILRNEKRMLQEAVDALFDNSRKANAVKTGESNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELQLHQCGLPKSMAIELFQPFVIRRLVERGIAKSVKSAKKLIDKKDPVVWDVLEKVIDGRPVLLNRAPTLHRLGIQAFQPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSQEAQLEASLLMLSSHNLILPQSGKPVTVPSQDMVLGMYYLTKARFGDVGQGQLFYSMEEVIIAYNEERAGLHAQIFVKYDGKVDQVSDPVRLVDTLVPEEQAERRAWLKSQIEQKKVLVTTVGRVIFNQHMPEKIGFINKLINKKVAKELIAHLSSQVGNVETAQFLDNIKAVGFGYAMRGGLSIGLSDAIVPETKVKHIKNAQRDSAKVVKEYNRGTLTDNERYNQIVDVWQKTSNLVADESYQKLKNDRDGFNPLYMMLDSGARGSREQVRQLTGMRGLIARPQKSMSGQPGEIIENPIISNLKEGLTVLEYFISTHGARKGLSDTSLKTADAGYLTRRLHDVAQDVIVTIDDCGTTRGLHVERNIEEETSGQIKFREKIKGRVAARDIVDVINDKVVVKAGEIITDELAAAIQDNIGVEEAEIRSVLTCESKVGICSKCYGTNLSVHKLVEMGEAVGVIAAQSIGEPGTQLTLRTFHQGGAAQGGISETETKAFYEGQVELEDVKSVEHSIITEDGIEETRQIVIQKNGKLNIIDPDSGKVLKRYVVPHGAHINVENGQMVRKDQVLFSSEPNSTQILAEMPGFAKFIDIEKGVTYKEEVDPQTGFAQHTIINWRSKLRASETREPRIAIVSESGEIKKTYPVPIKSNLYVEDGQKLNPGDTIAKVPRNLDRVGGDITAGLPKVTELFEARIPTDPAIVSEIDGYVSFGSQRRSSKEIKVKNDFGEEKTYYVQVGKHVLATEGDEVKAGDPLTDGAVSPQDILRIQGPNAVQQYLVNEIQKVYQINAGVEINDKHLEVIVRQMLQKVRVEEAGDTNLLPGDLIDRGTFIEANEAVAEKVRVIDRGDAPPRIQEGQLYKQRDITKLNRELRRNSKSLITIEPALQATSHPVLLGITSAALQTESVISAASFQETTKVLTDAAVAGKVDHLAGLKENVIVGKLIPAGTGLRKYRSIRLQSNEPEEVDVIESASTGDAEEEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DGTL1_LEPBJ
Sequence: MYFSRNDLIQKEIAGLAPYAISSTNNGGRFYEEEEHSYRLPFQRDRDRVLHSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSHLSESIALAHDLGHTPFGHAGQEILSSLMKDHGGFEHNKQSLRIVTSIEKKYPNFPGLNLCRETLKGLMKHGTEYDPSMMLLERKESGPSLEGMIADLSDEIAYTSHDIEDGWEMGYLHLGDLSENPFWKEVYEECKEQYKDVGEKILVRTAIRTLTNSMVSDLIQNISLQLETNQVKSTEDLIRLWKQGIRIASFSERVDSKFRELKFFLYEKLYRHEDLVRMSDYGKKVIESLFDYFLKHPEKIPDTYKERIEEESLYRVISDYVAGMTDRYAEKIYQSLH
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: FDHE_SHESR
Sequence: MSHTAEIPMVPGSESPLELKPLKAVDPKTVYHRRAQRLLSLAKDSPLADYFELCRRVVAIQARLAAEADFGQLLAWGKDEAIPLSHLGSEADSYWQGLLQQLLSDLLPQVDEDMARVLRLLMQQSPEQLTSWGSALRQGHMSEVPARFSLFIWAAMGVYWSHWAPMVIKRIDQRKVVQQNLCPICGCHPVASVIVDQPRAGLRYLHCSLCESEWHYIRAHCTSCGQDKGTTLWSFDDAKAQVRIESCDECHGYTKMLFVEKSPLMDVAADDLATLMLDSELNAKGFGATTVNPLLLAHETEQ
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPXS1_DICDI
Sequence: MKFGKKLRFECVSEWHNKYISYGKLKKYLRYLYRSDLKQIGEAEEAHLLINGFPSLSDSQEQFKQLSNSSSPIFNDGSCLENSLDSSIGSNIIQEQSQHQQQAQQQPPQQAQQQPPQQAQQQAQQQAPQAQQQAQQQAQQPEQQQQQDLKESFNDITGYSIDQYEDTSNLDEKTPLISILDQSRPTTTTTTTTTTMNTSAGSGIFKNKKPKQIPTISIPVFSQSERERLFLSKIDEELRKINEFFSNKEKDIILHYNKLTEHCSLILKDRNPSPKVLKNIQKAFGELYKGLTMLENYVNLNYQGFEKILKKYDRLAPMNSSIKLDQMERIKLEKFHSSKSWRNMKEDVELLYCKIFKLDKISIAKKKLAPFSESQSADYHMLKLGFAIGLSIGILAFVIILFTNKSLNQHPDWTRFVSTIPIFRAVGIPILAVWLWGVNVYIWDNARVNYILIFGLDPRTSIDHRRIWKTASFLTAIWLTMFLLFCGTVTGNFALGDVPAQVYPLVLVIFFLSVVFFPFRFFHRKSRTLLFITLGNVIITPFGSTKFRALFLGDLLTSMVKTIFDFEYTACYFFTGDWMINDSTRCNQVNSIALPILSGLPLLWRFMQCILRYRETNNKIHLGNSTKYAVGFSVVLFSALNGNYQAYEPWSASRILWCVCFVLSTLYMYCWDVVVDWGFMWLGKPRPLLRHQLMYKRHMWSYYYVLFSNLILRFAWTLTITRIPFELPINSELFNTITASIELVRRFTWSIFRVENEHICNSIQYHAFDFSEAPWKNEVPKVESPKSLLPLSSSYPYRQDNFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNINNINNINNNNNNSPSGSNSSINNSFHLGSSSYSYDNQYSIWKKSSKQYYSTSLIDSIKKKFFNNNNSNNNKK
What are the official names of this protein?
SPX and EXS domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PEPT_EXIS2
Sequence: MKHDLIRRLTTYAKIDTQSDYASTTVPTTDGQWTLARLLVDELKEIGMSDVTVDANGYVMATLPANTDADIPTIGFLAHLDTATDFTGTNVNPQIVEAYDGEDLVLNATLPVILSPKDFPALKNYVGHTLMTTDGTTLLGADNKAGIAEIMTAMHHLITHPEIKHGRIRVAFTPDEEIGRGPHHFDVAAFDAKFAYTVDGGPLGELEYESFNAAAAEIIFHGTNVHPGTAKDKMVNSQKHAMAFQNRLPGDEAPEFTDGFEGFYHLISFEGSVEKTTVQYIIRDFDRSKFEARKHFLTALVEEWNKKYGAGSVEIKLNDQYYNMREKIEPHMEIVDIAHAAMESRGVTPIIKPIRGGTDGSQLSYMGLPTPNIFTGGENYHGKFEFISVDNMVKATEVVVAIAERFAQSAK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_BACC0
Sequence: MFQKVEGIVIRTTDYGETNKIVTIFSRELGKVSAMARGAKKPKSRLASVSQLMTHGHFLIQMGSGLGTLQQGEIISTMKEIREDIFLTAYASFIVELTDKATEDKKHNPYLFEMLYQTLHYMCEGVDPEVLSLIYQTKMLPVLGMRPYFDTCAICHQETDFVAFSVREGGFLCSRHAEQDQYRIPVGEAVHKLLRLFYHFDLHRLGNVSVKDSTKKQMRLVLNTYYDEYCGIYLKSRRFLEQLDKFQI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TOP1_MOUSE
Sequence: MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKDKDKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKERRKEEKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAPPKEDIKPLKRLRDEDDADYKPKKIKTEDIKKEKKRKSEEEEDGKLKKPKNKDKDKKVAEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.  Involved in the circadian transcription of the core circadian clock component BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the BMAL1 promoter.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli.
Protein: NOP10_HALMA
Sequence: MKSDIHVCAVWESEHDRPVYTLDDTCPECGAEAVNSAPAPFSPEDSYGEYRRSLKRRSRE
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: NKAI3_XENTR
Sequence: MGCCTGRCTLIFICTLQMLVALERQIFDFLGYQWAPILGNFLHIIVVILGLFGTIQYRPRYIVAYTIWTAFWVAWNVFIICFYLEVGGLSKDTDLMTFNISIHRSWWREHGPGCVWRLVPAPPSKNLGDHSFISVTGCIIEFQYIEVIHSAVQILLSLIGFVYACYVISVITDEEDSCRHK
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AKAP6_HUMAN
Sequence: MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHTGADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR
What is the function of this protein?
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum.  May act as an adapter for assembling multiprotein complexes.
What are the official names of this protein?
A-kinase anchor protein 6, AKAP-6, A-kinase anchor protein 100 kDa, AKAP 100, Protein kinase A-anchoring protein 6, PRKA6, mAKAP.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
Protein: CSS4B_HALNC
Sequence: MEVMRVRSDLIATRRIPGLKNISLRVMEDATGKVSVACDPIGVPEGCWVFTISGSAARFGVGDFEILTDLTIGGIIDHWVT
What is the function of this protein?
Unlike beta-carboxysomes, alpha-carboxysomes (Cb) can form without cargo protein.  CsoS2 is essential for Cb formation and is also capable of targeting foreign proteins to the Cb.  The Cb shell assembles with the aid of CsoS2; CsoS1A, CsoS1B and CsoS1C form the majority of the shell while CsoS4A and CsoS4B form vertices.  CsoS1D forms pseudohexamers that probably control metabolite flux into and out of the shell.
What are the official names of this protein?
Carboxysome shell vertex protein CsoS4B.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family. CsoS4 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=Probably forms vertices in the icosahedral carboxysome (By similarity). This bacterium makes alpha-type carboxysomes (PubMed:19844578).
Protein: TIG_ALBFT
Sequence: MAVTVETLEKLERKMTLTLPVGIVESEVQSRLKKLARTIKMDGFRPGKVPMNVVSQRYGYSVHYEVMNDKVGEAFFNAANEAKLRVAGQPRISESEASPEGEMAFDAVFEVYPDVKIGDLSTAEVEKISAEVTDSAIDKTVDILRKQRRTFSQRPHDAAAQDGDRVTVDFEGKIDGEVFAGGKAEDFQFIVGDGQMLKEFEEATRGMKSGESKTFQMAFPADYHGKDVAGKTADFMVTLKKIEAAHLPDVDGALAKSLGIEDATVEGLRADIKKNLAREVKARLLARNKQAVMDALVGKAELDLPNASVQAEVNRLMEGARADLKQRGIKDADKAPMPEDIFRPQAERRVRLGLVVAELVRSNNLQATPEQVKAHIEELAASYEKPADVMRWYYSDNNRLAEVEAIVIENNVTNFVLAQAKVSDKALSFDELMAQN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RLMN_TREPS
Sequence: MEWCCALSGLLPEEIQKVCAFAERFRGVQVFRWIAAGCTDFHAMSDLSSETRARLARACVISDTRVYTTLRDVDGTLKLGIELKDKRRVEAVLLVDQVSRKTACLSCQVGCPMACAFCQTGQLGFARNLSASEIVEQFLHLERCVGTLDNVVFMGMGEPMLNLDAVCRAIEILSHPQGRDLSEKRITISTSGHCRGIYSLADRALQVRLAVSLTTANAPLRARLMPRAAHDSLAKLKSAIRYFNEKSGKRVTLELALMRGVNTSERHAQEVIDFAHGLNVHVNLIPWNPVASIHFETPREVEVAHFEALLMRARIPVTRRYQRGNGIGGACGQLGKTAGV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_PROMP
Sequence: MKLILRGIANEFIKSFSFKNFEIDQNFFDKLITKEAPAAANLITENEKINSYELAKLKLILEKHFIKLSNIYSNNRETVLSGKSLKINSTFLKIKDLENQLPLDPSYLKKDILHKGTVRSGDRISSNGDLFIIGDVNPGAIISANNNVYVWGKLFGIAFAGKNGNKNASVASLYLNPLQLRICEIVAIGPKEKPKGQHPEIAILEDNKIIIKPYFLNQNL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: REP9_ECOLX
Sequence: MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPNDESKENPLQPSPAEKVSPEMAEKLALPEKLGITLDDLEKLFKSR
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.  In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ (By similarity).
What are the official names of this protein?
RepFIB replication protein A.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: CU213_LOCMI
Sequence: GGPAAYSTYTNTADFGAVGATLESTSKGLGGLNTITQFSKAVDSPTSSVRISNSRVSNDYGSLGYGALPAPAGLAYGAAGASYGASLHGAGAYGVVRAAPAIAAAPALAYGARAIAAPAIAAPALAYGARAIAAPALAYGRGLAYGGAYGAALAAPALAYGARAYAAPALALGARAYAAPAIAAAPALAYGARAYAAPAI
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 21.3, LmNCP21.3.
Protein: RL1_PEDPA
Sequence: MAKKGKKFQDAAKQVEALKAYAPKEALELVKKIDFAKFDATVETVYKLNVDTKQADQQLRGAVVLPNGTGKEQTVIVFAKGAKAEAAKAAGADVVGDDDLVQRIQDGWLDFDVAIATPDMMGQVGRLGRVLGPKNLMPNPKTGTVTMDVEKAVADSKSGKVTYRTDRDGNVHVPIGKVSFDVDQLLGNLQTINDTIVRLRPASVKGAYVQNVSVASTFGPGVKVDFSQF
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YCF3_TETOB
Sequence: MPRSQRNDNFIDKTFTVIADILLKVLPTSQREKQAFTYYRDGMSAQAEGEYAEALQNYYEAMRLEVDAYDRSYILYNIGLIHTSNGEHGRALEYYYQALERNPSLPSALNNIAVIYHYRGEQAIENGQSEISQILFEKAADYWKEAIRLAPTNYIEAQNWLKMTGRNTGL
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CSPA_RICCN
Sequence: MATNIVGKVKWYNSTKNFGFIEQDNGGKDVFVHKSAVDAAGLHSLEEGQDVIFDLEEKQGKAYAVNLRIK
What are the official names of this protein?
Cold shock-like protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMVK_BOVIN
Sequence: MAPLGGVPGLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQRLMDASTYKEAYRSDMIRWGEEKRQADPGFFCRKIVEGVCQPVWLVSDTRRVSDIQWFQEAYGAVTQTVRVVATEESRQQRGWVFTPGVDDAESECGLDNFRTFDWVIENHGDEQHLEEQLEHLIEFIRSRL
What is the function of this protein?
Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites.
What are the official names of this protein?
Phosphomevalonate kinase, PMKase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: LPXK_RICCK
Sequence: MIKLLYPKFWQKQNIIAYLLLPVSLIYQFLGYLRASLAQPIMLPAKVICVGNCSVGGTGKTQIVIYLAKLLKARNVSFVIVTKGYGSKLKNAAIVNARHTVLEVGDEGVILVKYGLVIATKNIKEALPLINELKPDVIIVDDFLQNPHFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPNKALDAADLVFLVSSTNDKMLNILTPYVNKLINAQIVPLNNIDKTKNYFAFSGIGNPERFFSTLKNYGLNIVGYKIFPDHYNYLQADLENLYSLAKEHNNATLITTRKDYVKFHDLNNNIVCLDVELSINNPNLLNEKIFKKAQIFN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: AGOG_NANEQ
Sequence: MEDPLIKILKQFSIEDAKYVEYNLDRQFLALKENPKPVGLVIANALISYQLTMPGERYWELFAKKVNSFNDLYDFVKKYNPRFLSNKLKRLERFKPYIDIIEQNREHYYENMVALNKFLAKIMNQNIYDKTIVFSIKMFAYAMRALGYKFKPFPFEIAIPLDYRLKKINPDLNYWFYVSKQTNIPPLHIDSLIWPIFRIKNLPKKFALLKEYLSNL
What is the function of this protein?
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
What are the official names of this protein?
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, AGOG, DNA-(apurinic or apyrimidinic site) lyase, AP lyase.
What is the protein family that this protein belongs to?
Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
Protein: LNT2_TREDE
Sequence: MRFFLSFFIIFISSVLFSFGIPNEILNFGSAIAGFSGLVLVYYALLNCGSHKRAAFLYGFFVSFVHLMSSFWLAFFEDFAIFTLGASTLAYFFIAMPFGFLLYHSLQKRENLRPFFFAAIWLLWEFAKSTGFLAYPWGTAPMICFNLKPFIQFVDITGVWGLSFIVPLIAACLGEALQTYAYSANSKAFFKGLTEIKSPLIFTAFLVLIINIYGITILSIEMKPATFLNTVIVQQNTDPWDNSQFEENIKTSQALSRKAIFSANKKPDLIVWSESSLIVPYKDNEDFYGILPYDDPFTRFLADTDTPIIVGSPYIDGKKQYNAAYLLSPEGKILDIYSKIQLVPFAEYIPFIDNPLVVRFFDKLVGFSSGWNPGTEYKVFGIKNSEGKTVNFTVPICFEDAFPAVCLNLHNAGSEVLINITNDSWSKTKSAEYQHFVVAHFRAIELRTTLVRSTNSGYSVVVDPKGKIISDMPLFEAESVYTEVPVYGHKKTFYASYKDWLPIMMFLILIFNIFLEKRRAKTARF
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase 2, ALP N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CORZ_AEDAE
Sequence: MKHVFSTSLIVSLFVIFTDAQTFQYSRGWTNGKRSSPEQTAPSRTLLPHIPLGMDKPDEECRLLIQRFLKSPCDVRLANAIVNRNKDLLRDMADDVNDGTALLYDPVPMVDTAASEDVRFKRGTPDRRLLNDGMHRL
What is the function of this protein?
Cardioactive peptide.  Corazonin is probably involved in the physiological regulation of the heart beat (By similarity).
What are the official names of this protein?
Pro-corazonin, Crz.
What is the protein family that this protein belongs to?
Belongs to the corazonin family.
What are the subcellular locations of this protein?
[Corazonin]: Secreted. SUBCELLULAR LOCATION: [Corazonin precursor-related peptide]: Secreted.