PharMolix/UniProtQA huggingface dataset:
Protein: PSD_YERP3
Sequence: MLDSIKIKLQYLLPKQGLTQLAGWGANKQGGWLTQLVIKAFARYYKVDMKEAQDPEFSAYRTFNEFFVRPLRAGVRPVVAEENLLAQPADGAISQLGAIREGQILQAKGHNYSLEALLAGNYLLAAEFQNGQFVTTYLAPRDYHRVHMPCDGVLREMIYVPGDLFSVNPLTAANVPNLFARNERVICIFDTAFGPMAQILVGATIVGSIETVWAGTITPPREGVIRRWTYPQAGCEGAITLEKGQEMGRFKLGSTVINLFAEGKVYFAPQLNSGAVTRMGEVLAEAVPTTPSY
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VM3VB_MACLB
Sequence: MMQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPQKITALPKGAIQQPEQKYEDAIKYEFKVNGKPVVLHLEKNKGLFSEDYSETHYTPDGREITINPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGEMYLIEPLRIPDSEAHAIYKYENIEKEDEAPKMCGVTQTNWESDEPIKASQLNLTPEQRTYLKSKKYVELVIVADYIMFWKYDRSLSTIRTRIYEIVNTLNVIYRFLNIYIALVAVEIWSKGDLINVTSSAYDTLDSFGEWRERDLLNRKRHDNAQLLTGINFNGPSAGRGFVGRMCQPKYSVGIVQDHSKIYLLVASAMAHEMGHNLGMDHDRIDCTCGAKSCIMSGILRCETSYLFSDCSREEHRKYLINKMPQCILNKPLKTDIVSPAVCGNYFVEVGEECDCGSPANCQDRCCDAATCKLRPGAQCGDGVCCYQCKFRRAGTVCRPANGECDVSDLCTGQSAECPTDQFQRNGQPCQNNKGYCYNGTCPIMEKQCISLFGASATVAQDSCFQFNRRGNHYGYCRKENNTKIACAPEDVKCGRLYCLDNSSGHKNPCQIYYIPSDENKGMVDPGTKCGDGMVCSNGKCVDVTIAY
What is the function of this protein?
This metalloproteinase hydrolyzes azocasein, and insulin B-chain (at the '38-Ala-|-Leu-39' bond).  Also hydrolyzes the Aalpha-chain (FGA) and more slowly the Bbeta-chain of fibrinogen (FGB), without affecting the gamma-chain.  Cleaves alpha-chain of fibrinogen at '432-Lys-|-Leu-433' and '535-Pro-|-Met-536' bonds.  Does not cleave fibrin.  Inhibits endothelial cell adhesion to extracellular matrix proteins such as fibrinogen, fibronectin, vitronectin, collagen I, and collagen IV.  Induces apoptosis in vascular endothelial cells.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like VLAIP-B, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PQQA_PSE14
Sequence: MSWTKPAYTDLRIGFEVTMYFASR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: DUT_CHLTE
Sequence: MIKVKIVRLNQKAILPVYATAHAAGMDVSACLDAPVTVPSSASALIPTGFAIELPEGYEAQLRPRSGLALRHCISLPNSPATIDADYRGEVGVILINHGREPFTVSHGDRIAQMVVAKVDHVVFEEVESLSETARGEGGFGHTGVQAKAECL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: LEXA_SHEPW
Sequence: MRPLTPRQAEILELIKRNISDTGMPPTRAEIARRLGFKSANAAEEHLKALAKKGCIEIIPGTSRGIRLTQEEPEEVELGLPLIGQVAAGEPILAQEHVEQHYKVDPAMFRPSADFLLRVRGDSMKDIGILEGDLLAVHKSQQARNGQVVVARVEDDVTVKRFEKKGNKVFLHAENEEYSPIEVDLANQSLSIEGLAVGVIRNGDWQ
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ACPS_STRAW
Sequence: MSIIGVGIDVAEIDRFRASLERTPGLADRLFLERELLLPNGERRGIASLAARFAAKEAVAKALGAPGGLYWTDAEVWVEDSGRPRLRVTGTVAARAAELGVQSWHVSLSHDAGVASAVVVAEG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM182_DANRE
Sequence: MKIHVAGFFAGLFGALATLFILLSFGTDYWLLASETCNSHLNSPVTSERGDILVNQVHDPNSEAPNITFHHEGFFWRCTFDDVMNDGNLWKFWFENQPHVRVCKPAYLLPFPFPDQSYNTTSYQTAIIYRGFWSVSMLVGVAAVVAGGFIIICAAPFASHRLYKAGGGLYLISGFFVLVVTAMYVIWIDVLDVISLYTEYQKLNKCADFELNKTYGLSFMFAPVGVFFCFLSGLLFLVIGRTVHHQYN
What is the function of this protein?
May negatively regulate myogenesis and skeletal muscle regeneration.
What are the official names of this protein?
Transmembrane protein 182.
What is the protein family that this protein belongs to?
Belongs to the TMEM182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TILS_MESFL
Sequence: MERFKLNTTLSYLVAVSGGPDSMFMLNELIKMNIKEIVVCHVNYNFREDSWKDQKLVEDFCLKNNLKLEKLIINQDYSKLKENFESWARNIRYDFFVEISKKYNIQNVLIAHNRNDLVETFLLQQDRKGYVKHYGLNKTSTYKEITIVRPMLNILKSEILKSLKEENIAFVIDSTNEDKKYKRNKIRANLSESTFNDFEETIKKLNKKLEIINLEVNWYVNNNMSADELKINKNLQDQDLEFIQRTIYKWLEVIKKDFVIQNRRNKTIFEIAKNIKVSEKVFWEINIGEYSIIKDYENLFIIETKAIQPKTILIKSKEDLYLSEEFINWLDLLNAIKRNKENYPYVITNDFLTYKLNTYTFGKKTNRYLIDKKIRYKNRMLKAVVYSTKTKKILNTIK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJF_ECO45
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELU_SHEWM
Sequence: MSRNIIPKTTYQEIMLSGHPMIDVRAPIEFDKGAFPSSSNFPLMQDSERQRVGTCYKEQGQDAAIALGHSLVNGKVKQQRVDAWLAFIKQHPDAYLYCFRGGLRSQLSQQWIKEAGVDIPYVEGGYKAMRQYLIEVIDNAPAKQPVFILSGITGSGKTDFLLQRSEAVDLEGYAHHRGSSFGRYHEGQPTQINFENQLAVALLKHQERKEQCLLVEDESFLIGRSAIPKAFYEGMQNADILVLEEPEETRLTRLLNEYVHKMHSGYVERLGEEAGFTAFSEYLSQSITSIKKRLGSQLHDEFQTIISKALNMQLQQNDTQGHLEWISLLLTRYYDPMYQYQLEQKQERVIFKGSHQAMHEWLDHYRNR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: RPOB_GUITH
Sequence: MFNTTFANRTLPDLVEIQRASFCWFLNEGLAEEIQSFSPIVNYTGNLELHLFGDQYTLRYPKHNINECKRRDTTYSVQIYVPAQLINRETGVIKEQEVFIGDLPLMTDRGTFIINGAERVIVNQIVRSPGIYYKSELDKQGRRTYSSSLISNRGAWVKFETDRNDLVWVRIDKTRKIPAHVFLKAMGLSDTDIYNGLRHPEYLKKTFRFEGNYTTETALIQMYNKLRPGEPATVTGGQQLLYSRFFDPKRYDLGKVGRYKLNKKLNLSVPENVRVLTPQDTLAAIDYLINLKFEIGETDDIDHLGNRRVRSVGELLQNQVRIGLNRLERIIRERMTICDITSLTPNTLVNPKPIIASIREFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLNRDRAGFGVRDIHPSHYGRICPIETPEGPNAGLIGVLATHARINTYGFIEAPFFKVQDGQVYNHSQPIYLTADQEDKYRIAPGDITLDETNRIATKIVPIKYRQEFTTTKPNQVDFIAVSPIQVISIATSLIPFLEHDDANRALMGSNMQRQAVPLLYPESPLVGTGLEAQAARDSGMVVVSIEDGQVTFVSGDKICVTNKKGDEIAYYLQKYQRSNQDTCINQRPTVWLGEDVIEGQVIADGAATEGGELALGQNILVAYLPWEGYNYEDAFLINERLVYNDVYTSVHIEKYEIEARQTKLGSEEITRELPNVGEAALRKLDENGIIVIGSWVEAGDILIGKVTPKGESDQPPEGKLLRAIFGEKARDVRDTSLRVPNGGRGRILDVRIFTREKGDELPTGANIVIRVYIAQSRKIQVGDKMAGRHGNKGIISRILPRQDMPYLPDGTPVDLVLNPLGVPSRMNVGQIFECLLGLAAENLNKRFKITPFDEMHGAEASRVLVNEKLNEAKIKTGENWLFDLRHPGKITLYDGRTGEAFDNPVTIGVSYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGRAQHGGQRLGEMEVWALEAFGASYTLQELLTVKSDDMQGRNETLNAIVKGKPIPRPGTPESFKVLMRELQSLGLDIGAYKIENLPDGQTRGIEVDLMMNYQQSRLFKPLYESMQTKNNENLFL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y134_MYCGE
Sequence: MSFKKIAEMMRQAERETKKKTLAFEQQAFEYNYKNGAIKITILGDLTLKSINIDPVLIDASDKVILEEMIIEATNEAVSDVKTKYDNLVEKTMPKVPGLF
What are the official names of this protein?
Uncharacterized protein MG134.
Protein: PYR1_MOUSE
Sequence: MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIPSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSANCTLHEWLQQRGIPGLQGVDTRELTKKLREQGSLLGKLVQKGTEPSALPFVDPNARPLAPEVSIKTPRVFNAGGAPRICALDCGLKYNQIRCLCQLGAEVTVVPWDHELDSQKYDGLFLSNGPGDPASYPGVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDVFLETVREAAAGNIGGQTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITLHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRMKRIVTHAQLLEQHRGQALPQDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRAPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCHTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTGSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEEILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVIDCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPLQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGVVPQPPPSTPATTEITTTPERPRRVIPGLPDGRFHLPPRIHRASDPGLPAEEPKEKPPRKVVEPELMGTPDGPCYPAPPVPRQASPQNLGSSGLLHPQMSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVIVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPSVRDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSVQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF
What is the function of this protein?
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
What are the official names of this protein?
CAD protein.
What is the protein family that this protein belongs to?
In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.
Protein: RL24_NEIMB
Sequence: MNKIIKGDRVVVIAGKDKGKQGQVVRVLGDKVVVEGVNVVKRHQKPNPMRGIEGGIITKEMPLDISNIAILNPETNKADRVGIKLIENEGKVKRVRFFKSNGSIIGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AMGO2_RAT
Sequence: MSLRFHTLPTLPRAVKPGCRELLCLLVIAVMVSPSSSGLCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDADWIPVSFVKLSTLIVRHNNITSISTGSFSTTPNLKCLDLSSNRLKSVKSAMFQELKVLEVLLLYNNHISYLDPAAFGGLSHLQKLYLSGNFLTKFPMDLYVGRFKLADLTFLDVSYNQIASIPMHHINLVPGKQLRGIFLHGNPFVCDCSLYSLLTFWYRRHFNSVTDFKHDYTCRLWLDSRHSHQLLLLQDSFLNCSHSVINGSFHALGFIHEAQVGERAIVHCDGKTGNGNTDFIWVGPDNRLLEPDKDTGNFRVFYNGSLVIENPGFEDAGVYSCIAMNRQRLLNETVDIMINVSNFTINRSHHAHEAFNTAFTTLAACVVSIVLVLLYLYLTPCPCKCRDKRQKNALNQSNAHSSILSPGPTRDASAEDRKAGKRVVFLEPLKDPAVGQNGKVKLVPSKTVIAEGILKSSRAKSDSDSVNSVFSDTPFVAST
What is the function of this protein?
Required for depolarization-dependent survival of cultured cerebellar granule neurons.  May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3.  May contribute to signal transduction through its intracellular domain.
What are the official names of this protein?
Amphoterin-induced protein 2, AMIGO-2, Alivin-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. AMIGO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Nucleus. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
Protein: PAAE_ECOLI
Sequence: MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTLKASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGHFGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQALADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGPAAMMDDAETALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIVLNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYVLSCQALPLTSDVVVDFDAKGMA
What is the function of this protein?
Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA.  The subunit E is a reductase with a preference for NADPH and FAD, capable of reducing cytochrome c.
What are the official names of this protein?
1,2-phenylacetyl-CoA epoxidase, subunit E, 1,2-phenylacetyl-CoA epoxidase, reductase subunit, 1,2-phenylacetyl-CoA monooxygenase, subunit E.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FAD-binding oxidoreductase type 6 family.
Protein: SYP_NATTJ
Sequence: MSKNNEEFVKEITPQSEDYSQWYLDVIKKTKLVDYAPVKGCMVIRPYGYAIWEKMKEGLDRRIKETGHENAYFPLFIPESLLQKEADHVEGFAPEVAWITKGGDEELSESLAVRPTSEAMFGEMYSDWIQSWRDLPVLINQWANVVRWEKSTKPFLRTSEFLWQEGHTAHRTEEDAEEEALQMLDVYKDFVENDMAIPVLNGLKSEKEKFAGALRTFCIEALMSDGRALQAGTSHNLGQHFAKVFDITFLDQDDERKYVWQTSWGVSTRLIGALIMVHGDNRGLKIPPKVAPHQLVMVPITPKKQREQVLEESDKLYQELKDKFRVKLDNREEHTPGWKFNEWEMKGVPIRLEIGPKDIEKDQVVLVRRDTDEKMFVKRDELIDKLEELIEDIQNKMLQTAKNFLEENTHTASSLDELGQILEQKRGMIKAYWCGNQACEEKVKDDTKATIRVIPFEAETGGSCIACGYHNDDNKEVFFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_VIBA3
Sequence: MASVSTNEFKGGLKFMLDNEPCAIIDNEYVKPGKGQAFNRVKLRKLLSGKVLEKTFKSGESFELADVVDVELGYLYNDGEFYHFMNNETFEQIAADVKAVADSAKWLVENDVCTLTLWNDNPITVTPPNFVEIEVTETDPGLKGDTQGTGGKPATLATGAVVRVPLFIAIGEVVKVDTRTGEYVGRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAST_DROPE
Sequence: MVRTKNQSSSSSASSSSHKSPIKSHGGSGSAAAGTAGHPVSRSSSSHRTSIDDRKSATNVSSSSNRRTTPGSSPDGDGDDDTTTTDDLTPTSTSAPRSAGGPSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNNSNNKDQKHQQLTSSQSLNYPLEVTSGEAASEQQVQQPLPQQRYRALQPLEMAGANRSGSGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREEDFQMHRLSLKEKQKANESREQQQKPQKAREAADKPMLTNLTNDPAKLKTRSSGYGPKNGLTTPRIFATATTPTSSSSLASGRKLTIGTKRPGNLAVAANKSQTLPRNLGSKTSVGAVRQPGKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGASGSGSGASTPVVTVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQEVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHLQPSIIFIDEVDSLLSERSSGEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTDALRRLSKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDINAMRHITEKDFHNSLKRIRRSVAPQSLSLYEKWSSDYGDITI
What is the function of this protein?
ATP-dependent microtubule severing protein.  Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle.  Regulates microtubule stability in the neuromuscular junction synapse.  Involved in lipid metabolism by regulating the size and distribution of lipid droplets.  Involved in axon regeneration by regulating microtubule severing.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome. Lipid droplet. Note=Forms an intramembrane hairpin-like structure in the membrane. Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules. Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles.
Protein: KCY_CLOBM
Sequence: MLNISIAIDGPAGAGKSTIAKIIGNKLNIMYINTGSMYRAVTLMALKNNIEPSDIESLKTLINSMDISFNGNNIIVNGKDLEEAIRMPIINNNVSKYAAVEEVRELLVSMQQNISQKYNVVMDGRDIGTVVLKDAPYKFFITASAEVRAKRRLKELKEKKINISFQDVLKEIKERDYIDSNRKVNPLKQSKDAILIDTSNFTIEEVVDKICSIIKRD
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDHC8_ARATH
Sequence: MVRKHGWQLPAHTLQVIAITVFCLLVVAFYAFFAPFVGGRIWEYVLIGVYSPVAILVFVLYVRCTAINPADPRIMSIFDTGVNGDGMVRGLSRNYDETGSQLQASPSVVSRSSTVAGNSSVKGSVEDAQRVESVSRRSCYNPLAVFCYVFVVEDCRKKEGPAEEQGNSEEALFCTLCNCEVRKFSKHCRSCDKCVDCFDHHCKWLNNCVGRKNYVTFVSLMSASLLWLIIEAAVGIAVIVRVFVNKQTMETEIVNRLGNSFSRAPLAAVVGLCTAVAIFACFPLGELLFFHMLLIKKGITTYEYVVAMRAMSEAPDGASVDEEIQNVLYSPTGSATTGFSGGSSLGLPYRGVWCTPPRVFDNQDEVIPHLDPCMVPSTVDPDAPGSEKGTKALKRPVKRNAWKLAKLDPNEAARAAARARASSSVLRPIDNRHLPDNDLSSIGTVSIISSVSTDANVAASKEIRNNDLRSSLSRNSFAPSQGSRDEYDTGSHGMSNLSSPSHVHESVTLAPLPQNPTIVGNRFTATSHHMHSTFDDKVLHRGNDADPLFLFAPATSHLRDVRKTSVVWDPEAGRYVSAPVTTTSEVRNRLLNPSSQTASTQNPRPILPAHDSSSGSSALRDPLPLHQAERRLTYTGDSIFYGGPLINIPTRDTPRSGRGLVRDVQDRLASTVHRDARIRRDSTSNQLPVFAPGGLGANSQTGSNIK
What is the function of this protein?
Palmitoyl acyltransferase.
What are the official names of this protein?
Probable protein S-acyltransferase 20, Probable palmitoyltransferase At3g22180, Zinc finger DHHC domain-containing protein At3g22180.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: LGT_NITEU
Sequence: MLVHPQFDPVAISIGPLAVRWYGLMYLLGFSLFILLGRYRIRQQPNGVFTREMLDDALFYGVLGVILGGRLGHVLFYEPGYYLQHPLEILAIWQGGMSFHGGFLGVAIAMLCLARKYQLSWLAVTDFIAPLVPLGLGAGRIGNFINGELWGRPTDVPWGMIFPYADNLPRHPSQLYEFALEGLVLFALIWLYSAKPRPLGAVTGMFMIGYGAFRSFCEFFREPDDGFLGIMTLGISMGQWLSLPMIAAGIALLYWAYRYDGKPEKAARKLPRERKNRD
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_MALP2
Sequence: MNNINSNKHISVRLEDAVDSLNIQKDKIYVDCTFGRGGHSFEILKRLSSKGKLFVFDLDLDAKKYFDNNFSKFKNCFFIQDNFKNLKENLAKFDISKVDGFLFDFGVSSPMLDNANRGFSFKLDARLDMRMNQNQELSAYEVINNYSKEKLIQIFWKYGEIRNPVPVVDEIIKYRSNKPIETTLELVDIIRKRTPIKIQREKKHFARTYFQAIRIEVNDELNSIRKALSDALNMLSKNGRIVTISFHSLEEKEIKNTYKDVLESKIPKEVPINNSFDFKIIKIKPKRASSSELEENNRTRSSFLKVIERVNE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_POLSJ
Sequence: MAVIKMKPTSPGMRGMVKISRDHLHKGEPYAPLLEPQFQKSGRNNNGHITVRHKGGGHKHHYRVVDFKRNKDAIPAKVERIEYDPNRTAHIALLCYADGERTYIIAPRGLEVGATLISGSEAPIRVGNTLPIRNIPVGSTIHCIEMQIGKGAQIARSAGTSATLLAREGTYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRRLGKAGVKRWMGIRPTVRGVVMNPVDHPHGGGEGKTGEGRHPVDPWGNLTKGYRTRNNKRTQVMIVSRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.