PharMolix/UniProtQA huggingface dataset:
Protein: SOMA_ICTPU
Sequence: MARVLVLLSVVVASLLFSQGATFESQRLFNNAVIRVQHLHQLAAKMMDDFEEALLPEERKQLSKIFPLSFCNSDSIEAPAGKDEAQKSSVLKLLHTSYRLIESWEFPSRNLGNPNHISEKLADLKMGIGVLIEGCVDGQTGLDENDSLAPPFEDFYQTLSEGNLRKSFRLLSCFKKDMHKVETYLSVAKCRRSLDSNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: M17L2_BOVIN
Sequence: MPPGGWRWLRGLWAAGQPLFQGRALLVTNTLGCGVLMAAGDGARQTWEIRARPGQKFDPRRSVSMFAVGCSMGPFLHYWYLWLDRLFPASGFPGLPNVLKKVLIDQLVASPMLGVWYFLGLGCLEGQTLDKSCQELRDKFWEFYKADWCVWPAAQLVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRIPGPLTPPGCVALGTIQTEPPDARQQGKTD
What is the function of this protein?
Required for the assembly and stability of the mitochondrial ribosome (By similarity).  Is a positive regulator of mitochondrial protein synthesis (By similarity).
What are the official names of this protein?
Mpv17-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Mitochondrion inner membrane.
Protein: PURA_ECO27
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_NEIG1
Sequence: MITLAVESMGGDQGLAVTVPGATAFLQAHPDVRLIMTGDETQLRQALNAAGAPMERIDICHTTQVVGMDESPQSALKNKKYSSMRVAINQVKEGKAQAAVSAGNTGALMATARFVLKTIPGIERPAIAKFLPSDTDHVTLALDLGANVDCTPEQLAQFAVIGSELVHALHPQKGQPRVGLVNVGTEDIKGTDTVKQTYKLLQNSKLNFIGNIESNGILYGEADVVVADGFVGNVMLKTIEGAVKFMSGAIRREFQSNLFNKLAAVAALPALKGLKNKLDPRKFNGAILLGLRGIVIKSHGGTDKTGFRYALEEAYHEAKSAGLSKIEQGVAEQLAALEAAQNETAASL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: GET1_LACTC
Sequence: MVNSTILVTVVLVLALRALQWCSGYQHKFIDMIWCKPVALKLQGLIKKRRELHLAQQSTSAQDEYAKWTKLNRQIAQLDTQVKQTQEQLVENRKVGEKNLGKLRLVFFTAPLLVLRFWKGKLPVYALPSGMFPRVVESVLSQGWAAAALAPVRFVWASGTVKPMQVETPVCLAIWLWALSRVLDTSEFVVRSLCM
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: KINH_HUMAN
Sequence: MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGGKQV
What is the function of this protein?
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.  Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity).  Regulates centrosome and nuclear positioning during mitotic entry.  During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726).  Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).  Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable).  Involved in NK cell-mediated cytotoxicity.  Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (PubMed:24088571).
What are the official names of this protein?
Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
Protein: OM14_YEAS7
Sequence: MSATAKHDSNASPNSDSEDGHHHNNKKECAIEYLKARLNSASAVACGYLQAFVSKTQDFAKVCFLELQNPVVLVNLLLHSSVVCYLCNGYANHNARFLKGKPNSTVLATTAGALGLLTLDGIISKKYYSRYDKK
What are the official names of this protein?
Mitochondrial outer membrane protein OM14, Outer membrane protein of 14 kDa.
Protein: SYY_XYLFA
Sequence: MSLVSNSLALIERGANEILKFDELERRLRSGRPLRIKAGFDPTAPDLHLGHTVLLNKMRQFQELGHQVIFLIGDFTGMIGDPTGKNVTRKPLSHEDVLANARTYEDQVFKVLDRTLTEVRFNSEWFGKMSAVDMIKLAAQHTVARMLERDDFAKRFVSQQPIVIHEFLYPLIQGYDSIALRADVELGGTDQKFNLLMGRALQEHHGQPPQVVLTMPLLEGLDGVAKMSKSLGNYIGIKEPPIDIVTKTMKIGDDLMWRWIELLSFKISAAEVVALREAVAKSELNPREVKLRLAHELVSRFYDNAAAEKAIAGWQAVVTGQGNNNLLPLQKINVPADGVRLVALLTKSGLAPSNSEAMRKLKERAVRVDGIVVDDAHLHFVPGFEGLIQIGKRNFAKVRLVTSSESHDFPESNGIDKS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCF_ARATH
Sequence: MSSGGAGEYNEDRHLLRSTDGDEVGIGGGEGDLDVESQSPAIRSGAGGVRDLFKHIDRRFSLSGRRLSFKRMENIRVDRERHNPSSSSAFSAAGEEDGGGISNLHSVDDRNDEYGFDEEVLGDSAPPEWALLLIGCLIGVAAGICVAGFNKGVHVIHEWAWAGTPNEGAAWLRLQRLADTWHRILLIPVTGGVIVGMMHGLLEILDQIRQSNSSQRQGLDFLAGIYPVIKAIQAAVTLGTGCSLGPEGPSVDIGKSCANGFALMMENNRERRIALTAAGAASGIASGFNAAVAGCFFAIETVLRPLRAENSPPFTTAMIILASVISSTVSNALLGTQSAFTVPSYDLKSAAELPLYLILGMLCGAVSVVFSRLVTWFTKSFDFIKDKFGLPAIVCPALGGLGAGIIALKYPGILYWGFTNVEEILHTGKSASAPGIWLLAQLAAAKVVATALCKGSGLVGGLYAPSLMIGAAVGAVFGGSAAEIINRAIPGNAAVAQPQAYALVGMAATLASMCSVPLTSVLLLFELTKDYRILLPLMGAVGLAIWVPSVANQGKESDSSEGRSTGRGYSSLSPSERKTEGVWRHTDNADSLELTVIENPDHNSFLDEETILEDLKVMRVMSKNYVKVSSGTTLREARNILKESHQNCIMVVDDDDFLAGILTHGDIRRYLSNNASTILDENTCPVSSVCTKKISYRGQERGLLTCYPDATVGVAKELMEARGVKQLPVVKRGEVIHKGKRRKLLGLLHYDSIWTFLRDEMSRRRSINDRRKDKEVGTNGH
What is the function of this protein?
Voltage-gated chloride channel.
What are the official names of this protein?
Chloride channel protein CLC-f, AtCLC-f, CBS domain-containing protein CBSCLC1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL20_RUBXD
Sequence: MARASRSIHARKKRRKLLKEARGYRGTKHTSYKRAKEQVWKSGVYAYVGRKQKKRDFRALWIQRINAAARRHGLSYSRFVHGLRLAGFDLDRKVLADLAVSEPEAFGAVAAQAKNALEGRPVERRVELGGAGR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CCSA_PELHO
Sequence: MIFLTLEHILTHISFSVVSIVITIHLINLLVNEIVGLYNSSEKGMIVTLFCITGFLIIRWIYSGHFPLSNLYESLIFLSWNFSIINMLPYLKNLKNHLREITSPSTLFIQGFATSGLLTQIHEQKILVPALQSQWLMMHVSMMILSYASLLCGSLLSIALLVITFRKSRSVVGKRNKFLNRIFSNIQYINEREKILLKTSFTYSINYYRSHLLQQFDFWSYRIISIGFLFLTIGILSGAVWANEAWGSYWSWDPKETWAFITWTIFAIYLHIREKKNAEGVKSAIVASIGFLIIWICYFGINILGIGLHSYGSFPIS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: WARA_DICDI
Sequence: MASIVMKSQHSLGYPNIGNINRSDYDSYEQQYNNPTGSKQYNNNNNNNTNTNEINNGTNTNLNPNNMYGMYNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNINNNNNNNNNNNNNNNNNNQHLSQSQQLSPTPYSSNSFSKLLSRSTNDLMLDQDDPSKKKRKRTSPDQLKLLEKIFMAHQHPNLNLRSQLAVELHMTARSVQIWFQNRRAKARNMEFKPQLSHGGSDLIYNALGSQNGMNSMGGGGGNGGGNGGGGMNGINNILNGNHNRNLNKYIPHGGNSINGNMGGGGGGGGGSHNHHHHNHNHNHHNHNHNHNHNQPLSNGDCGEKFSVASAWNKILLHPNNIDFLIRYNPDDPNSIDVNARDSKGLSLLFTAAFLGYEYQVRRLIESGANPNIKDNQGNTPLIAASVLGNQPIVELLLEHRADPNLVNDEGVSPLFSACKGGHLQIASSLLDHDAEVSVKTKINGETPLHIASLKGFEKICKLLIETEAKASVIDSNNRTPLHHACIMGYFSIAKLLICNGADMNAIDIDGHTPLHTSSLMGHDLITRLLLENGADPNIQDSEGYTPIHYAVRESRIETVKFLIKFNSKLNIKTKNGQNLIHLSVQFASLMMGQMIFESKGCEIAADDSDDQGYTPLYLAAKAGKTNFVKYLLSKGASKKIALEKLIQENQDKEIIQMLESTVTKSSNNNNSNSNINNINNINNINNINSQPNTNSDNNNNNNNNNFNENYSNGNNEQSQPPGNKFEEDDEDDFYDRVYKKSYTNRIISNSFSYQQKLNSGNGISVNSGNLED
What is the function of this protein?
Putative transcription factor, that seems to be involved in anterior-posterior patterning of the slug, probably by controlling the proportions of prestalk and prespore cells.
What are the official names of this protein?
Homeobox protein Wariai, Homeobox protein 1, DdHbx-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_CHLL2
Sequence: MLAKRIIPCLDVTGGRVVKGINFEGLRDAGSILEQARFYNGELADELVFLDISASVESRKTTLEEVLKVSGEVFIPLTVGGGINSVDRAREIFMHGADKVSVNTAVVKEPELISRIAEKYGSQAVVVAIDVKKKDDRYMVHTHSGKIPTPLEAVEWAQMVQELGAGEILLTSMDRDGTQEGYDNDILAKVSTSVHIPVIASGGAGNLEHLYDGFTRGKADAALAASIFHFRQYSIRQAKQYLRDRGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INCE_HUMAN
Sequence: MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQGARVPSSLAYSLKKH
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.  Acts as a scaffold regulating CPC localization and activity.  The C-terminus associates with AURKB or AURKC, the N-terminus associated with BIRC5/survivin and CDCA8/borealin tethers the CPC to the inner centromere, and the microtubule binding activity within the central SAH domain directs AURKB/C toward substrates near microtubules (PubMed:15316025, PubMed:12925766, PubMed:27332895).  The flexibility of the SAH domain is proposed to allow AURKB/C to follow substrates on dynamic microtubules while ensuring CPC docking to static chromatin (By similarity).  Activates AURKB and AURKC (PubMed:27332895).  Required for localization of CBX5 to mitotic centromeres (PubMed:21346195).  Controls the kinetochore localization of BUB1 (PubMed:16760428).
What are the official names of this protein?
Inner centromere protein.
What is the protein family that this protein belongs to?
Belongs to the INCENP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome, centromere, kinetochore. Note=Colocalized at synaptonemal complex central element from zygotene up to late pachytene when it begins to relocalize to heterochromatic chromocenters. Colocalizes with AURKB at a connecting strand traversing the centromere region and joining sister kinetochores, in metaphase II centromeres. This strand disappears at the metaphase II/anaphase II transition and relocalizes to the spindle midzone (By similarity). Colocalizes with AURKB at mitotic chromosomes (PubMed:11453556). Localizes to inner kinetochore (PubMed:16760428). Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis (PubMed:15316025). Cocalizes to the equatorial cell cortex at anaphase (PubMed:11453556).
Protein: GLMU_LACGA
Sequence: MNKYVVILAAGKGTRMKSQLYKVLHKVCGKTMVEHVVNAAKGTNPDKIITVVGNGADSVKDVLAGQSDFAFQEQQLGTGDAVLAASDLLENLDGSTLVATGDTPLFTAETFNNLFKKHEESGNSATVLTAKAPNPFGYGRIIRDEDGNVLRIVEQKDGTPEELAVDEINTGVFCFDNKELFKALKQVGNDNAQGEYYLTDVLEIMRKAGHKVGAYEMPDFSESLGVNDRIALAQATKIMQRRINEEHMKNGVSFIDPDTAYIDSDVKIGNDTVIEGNVVIKGNTEIGSDCYITNSSRIVDSKIGNHVTITSSTLQEAQMDDNTDIGPNSHLRPKAVIRKGAHIGNFVEIKKAEIGENSKVGHLTYVGDATLGKDINIGCGTIFSNYDGVKKFHTNVGDHSFIGAGATIIAPVNIADHSFVAADSTITKDVARYDMAIARGRQTNKPDYWHKLPLSKDKEWE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PROMP
Sequence: MINSDNQKFSEIRFDWERDEILEILNYPLIDLMWEAQIIHRRFNQYKVQLASLFSVKTGGCEENCSYCSQSIYSSSQIKSHPQFEVEAVLNRAKTAKKEGADRFCMGWAWREIRDGKPFNSMIEMVKGVKELGMEACVTAGMLTDEQALKLADAGLTAYNHNLDTSPEYYKNIITTRTYQDRLETIKRVRNAGINVCCGGIIGLGEDNGDRASLLEVLSNMNPHPESVPINSLVAIEGTGLEGGKEIDSIEMIRMIATARILMPKSKIRLSAGRENLTKEAQILCFQCGANSIFYGDELLTTSNPSFQDDRKLLKDVGVLFNKDFEYCDKTVSTV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DRE2_KLULA
Sequence: MTVSRDSLVLIHPAVTQQPELLETIEKGSILSETTIVAQYLINKLNDGTISPDDEKYDVIYYVTPEKPEAIQFPPKLIPVLHKTLKPSGRLYGLSDTLKVDALINGFEIVSNNGSEYYWVKESREKKAPVSISLKGNMKNGASAPVALPSFKKLNKTQPIGSSPSAGLAVSLKKLPTFKKLTKKVSAIKLTDSDLEDDDDDLESDDSANNSKTKFFDDFDDPETGDSIDEDDLIAETEEDTITMIQCGKSKQRRRKACKDCSCGLKEMEEQEIESRRAKQQQVIKFSEEELTEIDFTIEGKKVGGCGSCALGDAFRCSGCPYLGLPAFKPGQSINLNSISDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: APA1_YEAST
Sequence: MSIPADIASLISDKYKSAFDNGNLKFIQTETTKTKDPKTSMPYLISHMPSLIEKPERGQTPEGEDPLGKPEEELTVIPEFGGADNKAYKLLLNKFPVIPEHTLLVTNEYQHQTDALTPTDLLTAYKLLCALDNEESDKRHMVFYNSGPASGSSLDHKHLQILQMPEKFVTFQDRLCNGKEHFLPTFNTEPLQDAKVSFAHFVLPMPESEETVDEDLLAMCYISILQRALTFFQDWLNENPELKKSYNLMLTKEWICVVPRSKAFSDEMKIGFNSTGYCGMILTKNDEVFSKITEKPELINDILLECGFPNTSGQKPNEYNY
What is the function of this protein?
Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5'-adenosyl) tetraphosphate (Ap4A) into ADP and ATP.  Can also use other Np4N' nucleotides (where N and N' stand for A,C,G or U) as substrates with equal efficiency.  Cannot catalyze the reverse reaction.  Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5'-phosphosulfate (AMPS) into ADP and sulfate, the reversible exchange reaction between inorganic phosphate and the beta-phosphate of a nucleoside diphosphate (NDP), and the synthesis of Ap4A from AMPS plus ATP.
What are the official names of this protein?
Protein APA1.
What is the protein family that this protein belongs to?
Belongs to the ATP adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL15_HYPNA
Sequence: MKLNELSPADGSTKKRMRVGRGVGSGKGKTAGRGVKGQNARSGVAVNGFEGGQMPIYMRLPKRGFTSPGSKNMSWVNLGRIAKAIEAGTLDASNVTEESLVAAGVVRKARDGIRLLAKGDAPQKLTITVTGASKAAVEAVEKAGGSVTVTGAPKDAAEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EF1B_SULIL
Sequence: MTDVLVVLKVFPDSDEVNLDNLYTDISNKLPKEYRIIRKETEPIAFGLNALILYVQMPEQTEGGTDNLEEVVNNIQGVSHAEVVGITRLGF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: CASB_HORSE
Sequence: MKILILACLVALALAREKEELNVSSETVESLSSNEPDSSSEESITHINKEKLQKFKHEGQQQREVERQDKISRFVQPQPVVYPYAEPVPYAVVPQSILPLAQPPILPFLQPEIMEVSQAKETILPKRKVMPFLKSPIVPFSERQILNPTNGENLRLPVHLIQPFMHQVPQSLLQTLMLPSQPVLSPPQSKVAPFPQPVVPYPQRDTPVQAFLLYQDPRLGPTGELDPATQPIVAVHNPVIV
What is the function of this protein?
Important role in determination of the surface properties of the casein micelles.
What are the official names of this protein?
Beta-casein.
What is the protein family that this protein belongs to?
Belongs to the beta-casein family.
Protein: 3SA4_NAJHA
Sequence: LKCNKLIPPFWKTCPKGKNLCYKMYMVSTLTVPVKRGCIDVCPKNSALVKYVCCNTNKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 4, Toxin CM-11.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RSH2L_ARATH
Sequence: MVVATTIALYASPPSSVCSTPHQISCDLDLTSRSSSTSSSMASSPQKPIVGGLSSLFSSASVKSSSSSSCSYSTAVDEFSSLRYDRSDDLKDLSFSSSFGYSPAKFVNSFRRDHQSPISVLHGPVSCSCSPPMRMSRDRNLDGSFRLGASRLFNGFVRKALGSCVDYELGSDSGLVDELTFPMEVDTIKPYARDLLRRAQLRHKIFNDESVIKAFYEAEKAHRGQMRASRDPYLQHCVETAMLLANIGANSTVVVAGLLHDTVDDSFMSYDYILRNFGAGVADLVEGVSKLSQLSKLARENNTACKTVEADRLHPMFLAMADARAVLIKLADRLHNMKTLYALSPVKQQRFAKETLEIFAPLANCLGISTWKVQLENLCFKHLYPNQHNEMSTMLEDSFDEAMITSAIEKLDQALKKAGISYHVLCGRHKSLYSIYSKMLKKKLTVDEIHDIHGLRLIVDNEGDCYKALGVVHSLWSEVPGKLKDYITHPKFNGYQSLHTVVMDNGTVPLEVQIRTQEMHLQAEFGFAAHWRYKEGGCKYSSFVLQMVEWARWVVTWHCEAMSKDRSSISSSDSIKPPLQVFRLTLEDCPASYKPNSSQDGPVYVIVIENDKMSVQEFPASSTVSDLLSRAGPGSSRWSMYGIPAKEELRPRLNQIPVSDLKWKLKMGDVVELTPKIPDESLTEYREEIQRMYDRGLAFSRPGTMVGWGS
What is the function of this protein?
Probable ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase that may be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses.
What are the official names of this protein?
Probable GTP diphosphokinase RSH2, chloroplastic, RelA/SpoT homolog 2, AtRSH2, ppGpp synthetase RSH2.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
What are the subcellular locations of this protein?
Plastid, chloroplast.