PharMolix/UniProtQA huggingface dataset:
Protein: MURE_BACFR
Sequence: MKLKEILTSIQPVKITGNQDIEITGVDIDSRQVESGHLFMAMHGTQTDGHAYIPAAVEKGATAILCEELPVELAEGVTYIQVADSEDAVGKAATTFYGNPSSKLELVGVTGTNGKTTIATLLYNTFRYFGYKVGLISTVCNYIDDEAIPTEHTTPDPITLNRLLGRMADEGCKYVFMEVSSHSIAQKRISGLKFAGGIFTNLTRDHLDYHKTVENYLKAKKKFFDDMPKNSFSLTNLDDKNGLVMTQNTKSKVYTYSLRSLSDFKGRVLESHFEGMLLDFNNHELAVQFIGKFNASNLLAVFGAAVLLGKKEEDVLVALSTLHPVAGRFDAIRSPQGYTAIVDYAHTPDALVNVLNAIHGVLEGKGKVITVVGAGGNRDKGKRPIMAKEAARASDRVIITSDNPRFEEPQDIINDMLAGLDTEDKKKTLSIADRKEAIRTACMLAEKGDVILVAGKGHENYQDIKGVKHHFDDKEVLKEIFSLTV
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDA2_YEAS8
Sequence: MSMQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNSNECYLITILWLHK
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: TPIS_CHLAA
Sequence: MRIPLIAGNWKMYKTVGEATTLVRDLLAGLGELSDREAIVCPPFTALAAVAALVADSPLGLGAQNLYPEAQGAFTGEVSPPMLVDIGCRYVIIGHSERRQYFGESDAFVNRKLRAALAHGLRPIVCVGESKPQRDAGQAEPIVTAQVRAALLEVPPDQMANVVIAYEPIWAIGTGDTATPADAQAMHAAIRATLAELYGSEIAATVRIQYGGSVKPDNIDELMAQPDIDGALVGGASLQAASFLRIIHYQ
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O1493_RAT
Sequence: MNNKTVITHFLLLGLPIPPEHQQLFFALFLIMYLTTFLGNLLIVVLVQLDSHLHTPMYLFLSNLSFSDLCFSSVTMLKLLQNIQSQVPSISYAGCLTQIFFFLLFGYLGNFLLVAMAYDRYVAICFPLHYTNIMSHKLCTCLLLVFWIMTSSHAMMHTLLAARLSFCENNVLLNFFCDLFVLLKLACSDTYVNELMIHIMGVIIIVIPFVLIVISYAKIISSILKVPSTQSIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSGDNFSLKGSAMAMMYTVVTPMLNPFIYSLRNRDMKQALIRVTCSKKISLPW
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1493, Olfactory receptor-like protein I8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDD_ECO24
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAENADAPLIQWDATSATLKALGCHSIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: UBID_SALCH
Sequence: MDAMKYHDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYAMPVLCNLFGTPKRVAMGMGQDDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIASGDDVDLTRLPVMTCWPDDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDFQEWLAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCLSNDLEVPASAEIILEGYIEPGEMAPEGPYGDHTGYYNEVDNFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTMKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIVKDPEVTARIDAIWDELAIFK
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DITCY_MYCTU
Sequence: METFRTLLAKAALGNGISSTAYDTAWVAKLGQLDDELSDLALNWLCERQLPDGSWGAEFPFCYEDRLLSTLAAMISLTSNKHRRRRAAQVEKGLLALKNLTSGAFEGPQLDIKDATVGFELIAPTLMAEAARLGLAICHEESILGELVGVREQKLRKLGGSKINKHITAAFSVELAGQDGVGMLDVDNLQETNGSVKYSPSASAYFALHVKPGDKRALAYISSIIQAGDGGAPAFYQAEIFEIVWSLWNLSRTDIDLSDPEIVRTYLPYLDHVEQHWVRGRGVGWTGNSTLEDCDTTSVAYDVLSKFGRSPDIGAVLQFEDADWFRTYFHEVGPSISTNVHVLGALKQAGYDKCHPRVRKVLEFIRSSKEPGRFCWRDKWHRSAYYTTAHLICAASNYDDALCSDAIGWILNTQRPDGSWGFFDGQATAEETAYCIQALAHWQRHSGTSLSAQISRAGGWLSQHCEPPYAPLWIAKTLYCSATVVKAAILSALRLVDESNQ
What is the function of this protein?
Catalyzes the formation of tuberculosinyl diphosphate from geranylgeranyl diphosphate (GGPP).  It could also react with (14R/S)-14,15-oxidoGGPP to generate 3alpha- and 3beta-hydroxytuberculosinyl diphosphate.
What are the official names of this protein?
Type B diterpene cyclase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TREX1_BOVIN
Sequence: MGSRALPPGPVQTLIFLDLEATGLPFSQPKITELCLLAVHRYALEGLSAPQGPSPTAPVPPRVLDKLSLCVAPGKVCSPAASEITGLSTAVLAAHGRRAFDADLVNLIRTFLQRQPQPWCLVAHNGDRYDFPLLRAELALLGLASALDDAFCVDSIAALKALEPTGSSSEHGPRKSYSLGSVYTRLYGQAPPDSHTAEGDVLALLSVCQWRPRALLRWVDAHAKPFSTVKPMYVITTSTGTNPRPSAVTATVPLARASDTGPNLRGDRSPKPAPSPKMCPGAPPGEGLLAPLGLLAFLTLAVAMLYGLSLAMPGQ
What is the function of this protein?
Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini (PubMed:10391904).  Prevents cell-intrinsic initiation of autoimmunity (By similarity).  Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements (By similarity).  Plays a key role in degradation of DNA fragments at cytosolic micronuclei arising from genome instability: its association with the endoplasmic reticulum membrane directs TREX1 to ruptured micronuclei, leading to micronuclear DNA degradation (By similarity).  Micronuclear DNA degradation is required to limit CGAS activation and subsequent inflammation (By similarity).  Unless degraded, these DNA fragments accumulate in the cytosol and activate the cGAS-STING innate immune signaling, leading to the production of type I interferon (By similarity).  Prevents chronic ATM-dependent checkpoint activation, by processing ssDNA polynucleotide species arising from the processing of aberrant DNA replication intermediates (By similarity).  Inefficiently degrades oxidized DNA, such as that generated upon antimicrobial reactive oxygen production or upon absorption of UV light (By similarity).  During GZMA-mediated cell death, contributes to DNA damage in concert with NME1 (By similarity).  NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair (By similarity).
What are the official names of this protein?
Three-prime repair exonuclease 1, 3'-5' exonuclease TREX1.
What is the protein family that this protein belongs to?
Belongs to the exonuclease superfamily. TREX family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Retained in the cytoplasm through the C-terminal region (By similarity). Localization to the endoplasmic reticulum membrane is required to direct TREX1 to ruptured micronuclei. In response to DNA damage, translocates to the nucleus where it is specifically recruited to replication foci. Translocation to the nucleus also occurs during GZMA-mediated cell death (By similarity).
Protein: CYC6_CLITE
Sequence: SIPCGESCVYIPCITTIVGCSCKDKVCYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cliotide T6.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RUVA_RHOJR
Sequence: MIASVRGEVLEIALDHAVIESAGVGYRVNATPATLGGLQRGSEARLVTAMIVREDSMTLYGFPDSESKELFGLLQTVSGVGPRLAMATLAVLEPDALRAALAEGNVTALTRVPGIGKRGAERMVVELRDKVDAVASTSGAVPLGAGGGGSVRDQIVEALVGLGFPAKQAEQAADSVLAEAPESTTSTALRSALSLLGKTR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYP_METM5
Sequence: MEFSEWYSDILEKAGIYDLRYPIKGCGVYLPYGFKIRRYSFEILRKLLDETNHDETLFPMLIPENLLAKEGEHIKGFEDEVFWVTHGGKTPLEVKLALRPTSETTMYYMMKQWIKVHTDLPMKLYQVVNTFRYETKHTRPLIRLREIMSFKEAHTAHATKEDCDAQITEALNLYGEFFDEICVPYIISKRPEWDKFPGADYTMAFDTIYPDGKTMQIGTVHNLGQNFAKTFELEFETPDGEKDFVYQTCYGISDRAIASLISVHGDEKGLVIPVDVAPIQIVLIPLLFKGKEEIVMDKIKELNNTLKSEFRVHLDDRDIRPGRKYNDWEIKGVPLRIELGPRDIENGQALIVRRDTGEKITVEYSNILEEVEKIVSMYKENLKIKADEKIKNFLTVVNFESDVNALSEKVKAALLENKGIILIPFDESVYNEEFEELIDASVLGQTAYEGKDYISVARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNC5A_RAT
Sequence: MAVRPGLWPVLLGIVLAAWLRGSGAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDSSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSTSAAVIVYVNGGWSTWTEWSVCSASCGRGWQKRSRSCTNPAPLNGGAFCEGQNVQKTACATLCPVDGSWSSWSKWSACGLDCTHWRSRECSDPAPRNGGEECRGADLDTRNCTSDLCLHTASCPEDVALYIGLVAVAVCLFLLLLALGLIYCRKKEGLDSDVADSSILTSGFQPVSIKPSKADNPHLLTIQPDLSTTTTTYQGSLCSRQDGPSPKFQLSNGHLLSPLGSGRHTLHHSSPTSEAEDFVSRLSTQNYFRSLPRGTSNMAYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPVVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLRLKKQSCEGSWEDVLHLGEESPSHLYYCQLEAGACYVFTEQLGRFALVGEALSVAATKRLRLLLFAPVACTSLEYNIRVYCLHDTHDALKEVVQLEKQLGGQLIQEPRVLHFKDSYHNLRLSIHDVPSSLWKSKLLVSYQEIPFYHIWNGTQQYLHCTFTLERINASTSDLACKVWVWQVEGDGQSFNINFNITKDTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIIASLDPPCSRGADWRTLAQKLHLDSHLSFFASKPSPTAMILNLWEARHFPNGNLGQLAAAVAGLGQPDAGLFTVSEAEC
What is the function of this protein?
Receptor for netrin required for axon guidance (PubMed:9126742, PubMed:10399920).  Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1 (PubMed:19755150).  Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin (PubMed:10399920).  Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion (PubMed:10399920).  It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:11387206, PubMed:12598531).
What are the official names of this protein?
Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft. Cell projection, neuron projection. Note=The interaction with PRKCABP regulates its surface expression and leads to its removal from the surface of neurons and growth cones (PubMed:14672991).
Protein: YJDB_BACSU
Sequence: MNFKKTVVSALSISALALSVSGVASAHEINSTPTEVKNISISPTHVIKIQDYNLPLKVGETYSVKNNSATRYWTDNQKVAEVDQNGLVTAKSKGKATITLFKGTAVFGKVYVTVY
What are the official names of this protein?
Uncharacterized protein YjdB.
Protein: SSB_ONYPE
Sequence: MLNKVQLIGNITHDLEQQYINTNEGKIPKVNFQLAVNNKDTTQFIPCVVFRNQADNMFMYLHKGSKVYVEGTLSIEKYINNESENKTSTKVIVQRVIFLDNKNQ
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: M1_INBSI
Sequence: MSLFGDTIAYLLSLTEDGEGKAELAEKLHCWFGGKEFDLDSALEWIKNKRCLTDIQKALIGASICFLKPKDQERKRRFITEPLSGMGTTATKKKGLILAERKMRRCVSFHEAFEIAEGHESSALLYCLMVMYLNRGNYSMQVKLGTLCALCEKQASHSHRAHSRAARSSVPGVRREMQMVSAMNTAKTMNGMGKGEDVQKLAEELQSNIGVLRSLGASQKNGEGIAKDVMEVLKQSSMGNSALVKKYL
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: LOLA1_DROME
Sequence: MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQDLSRKENTAPDVASTAEIQRSFQRSILNGKQRDEQKIQLPGSRRKRLSVTEVSDMLFEFYKTKSAKVPKAEQPHRQVSPTSGEILDPSTISAIAVYGTASETASKNLNADEVMRVQNATATRVVGAAAGAAASFHPRPKYTLKTAASSTEHTTAIPTSVLVANSAAALTPKPQAAVIAEALMRNGLHNFQQQLRAQEILRQQTPHRRIKEENDVEIAGGDITPTKILENLLRKQQERDLRHSECENEPGYSTEDDEEGRYHAFDDIHLMEQSGGKFGNNSGMGMFNANAHGGSASSILDAHQAFRNLEFTLSDYGGSSSNGSTTSPNGIGLDGEPVYECRHCGKKYRWKSTLRRHENVECGGKEPSHQCPYCPYKSKQRGNLGVHVRKHHTDLPQLPSKRRSKYSMNRENGMSGSMSDDSQGKLIIDFNGKGELETK
What is the function of this protein?
Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems.  Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
What are the official names of this protein?
Longitudinals lacking protein, isoform G.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_CAUVN
Sequence: MTKAASGDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKIAFVKSKDGVPTPREICEVLDDYVIGQGHAKKVLAVAVHNHYKRLNHASKNNDVELAKSNILLVGPTGTGKTLLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIVLKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIISARGAAKSIGFGAKVTDPEERRTGEILRNVEPDDLQRFGLIPEFIGRLPVVATLEDLDEAALVKILTEPKNAFVKQYQRLFEMENIGLTFTEDALHQVAKKAIARKTGARGLRSIMEGILLETMFELPTYEGVEEVVVNAEVVEGRAQPLLIYAEKKGGAASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease (By similarity).  It directs the protease to specific substrates (By similarity).  Required for degradation of response regulator CtrA, thus contributing to the G1-to-S transition (PubMed:9755166).  Required to degrade DNA replication inhibitor toxin SocB, this function is probably the reason why the protease is essential in this organism (PubMed:24239291).  Can perform chaperone functions in the absence of ClpP (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PXPA_YERPE
Sequence: MKIDLNADLGEGCANDQALLQLVSSANIACGFHAGDAQTMRQSVRWALEYGVAIGAHPSFPDRENFGRTAMQLPPETVYAQVVYQLGALAAIVQVEGGVMQHVKPHGMLYNQAAVDPLLADAIAQAVKAVDPSLRLVGLAGSELIRAGTRVGLVTRQEVFADRHYQPDGTLVPRSQPDALIESDELALSQTLAMVQQHQVQACDGSWVQVQADTVCVHGDGVQALAFARCLRDRFQQEGISVIAQ
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SP5G_EXIS2
Sequence: MNVTDVKIRRVVAEGRMKALASITLDHEFVVHDLRVIEGNSGLFVAMPSKRTQEGIFRDVAHPINALMRKKVEDSVLEAYAIREENGEASELELAALEATDPS
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: Y6688_CANAL
Sequence: MSILINNGNDYQLNSSETFNSLKSSPSSTSSLSSISTSSSSSCHKRSKAVDLNRNTSNSQNSSISTAPTTATAANTTPRKTSITIPSKLPSSWIPLRNGNIDYSRYYNTNQEEDNQEQQLQDGEPLSAPTTNNGTTKTATANANIIQDSFETIPCFSSTTNTTITSSRSNPTNSTPTSNDPSFPKQMINWNQFLQEEKDMNDNSSTINDDDKTFYMEQLNLNVGQTPNNNNNNNHGVSETENDLLPGTSKSLIAKYHYQLNYGDENENETNDVREYEYGGGESRKRKSSTTSDDRRPRRGGGGGGSRTSQVFRNTLNKFTFKPKIK
What is the function of this protein?
Virulence factor involved in pathogen-host interaction.  Modulates host pro-inflammatory cytokine interleukin-1 beta (IL1B) expression.
What are the official names of this protein?
Virulence factor CaO19.6688.
Protein: MUTS_AERHH
Sequence: MTAQHQATGTAPGANLSAHTPMMQQYLTLKAENPEILLFYRMGDFYELFYDDARKASQLLDISLTKRGQSAGSPIPMAGVPYHAIEGYLAKLVQLGESAAICEQVGDPATSKGPVERKVIRIITPGTVSDEALLSERQDNLIAAVYHDGRRFGYGTMDIGSGRFFINQFEKEETLLAELQRTNPAELLYPESFTFLHHVEGRRGLRRRPEWEFELGTARKLLCQQFGTQDLVGFGVEQSETALCAAGCLMQYVKDTQRTALPHIRSVRLEQPDHAVIMDAATRRNLELTQNLAGGHDNTLSAVLDCTATPMGSRLLKRWIHQPIRDQVILKGRQSTIKELIEQNLYDELGGLLRQVGDVERVLARLALRSARPRDLTRLRQAFAQLPELQRLLAESEHEAVQQLRERASTFPELLDLLERAVMEVPPVLIRDGGVIRDGFNQELDELRDLANGATASLARIEERERLLTGINTLKVGYNKVHGFYIEVSRANSHLVPAHYIRRQTLKNNERYIIDELKKYEDKVLTAQAQALALEKRLYEELLDALLPHLGDLQESAAALAELDVLANLAERAETLDYRCPTLIDEDQILIEAGRHPVVEQVMTDPFIANPINLQRSRRMLIITGPNMGGKSTYMRQTALIVLLAHIGAFVPADSARIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILNNATARSLVLMDEIGRGTSTYDGLSLAWACAEQLASKIGAYTLFATHYFELTRLPELMEGLANVHLDAVEHGDTIAFMHAVQEGAASRSYGLQVAALAGVPKSVIQQARHKLHELESATPVAAGESRPAPVAMAPQSHPVVDELEAVRPDELTPRQALDLLYRLKQML
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PRL_CEREL
Sequence: MDSKVSSQKGSRLLLLLVVSNLLLCQGVVSTPVCPNGAGNCQVSLRDLFDRAVMVSHYIHNLSSEMFNEFDKRYAQGKGFITMALNSCHTSSLPTPEDKEQAQQTHHEVLMSLILGLLRSWNDPLYHLVTEVRGMKGAPDGILSRAIEIEEENKRLLEGMEMIFGQVLPGAKETEPYPVWSGLPSLQTKDEDARYSAFYNLLHCLRRDSSKIDTYLKLLNCRIIYNNNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIS12_SCHPO
Sequence: MLVELLEFTPLSFIDDVINITNQLLYKGVNGVDKAFSQTRFAKKAPQEIEEGLHKFEVLFESVVDRYYDGFEVYTLRNIFSYPPELKGYMRTFGKDVDYSITTEQDAAMDQAIQEAAEKLVVKMQLRRDLRMRLSRKREKKTEIEKHLERISFLNKVPENWQVTLPETTDFLLDQLGNLQHAVKRVVEASPTVHSREVDERITYLEKGYERLSNPIDQQKDFWSHHLSKLESTANTETANNIHKLLLSSEKDVGHTDEP
What is the function of this protein?
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle.  Required for correct segregation of chromosomes and for maintaining the inner centromere structure.
What are the official names of this protein?
Centromere protein mis12, NMS complex subunit mis12.
What is the protein family that this protein belongs to?
Belongs to the mis12 family.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore.
Protein: MINE_PROMP
Sequence: MMTLRDLINKLLGRETASANTARERLQLVLAHDRVDMSSLTTDLLDKMRKEILDVVAKYVEIDFEEVAVSLETEDRMTALVANLPIKRTLTGEIEFKKNEDTQKKK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: OPGC_SALCH
Sequence: MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFQKRQETSKPRPAAISLVRLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AQPZ_RHOPA
Sequence: MNTNKYLAEMIGTFWLTFAGCGSAVIAAGFPQVGIGLVGVSLAFGLSVVTMAYAIGHISGCHLNPAVTLGLAAGGRFPVKQIAPYIIAQVLGAIAAAALLYLIASGAAGFDLAKGFASNGYGAHSPGQYNLVACFVMEVVMTMMFLFVIMGSTHGKAPAGFAPLAIGLALVMIHLVSIPVTNTSVNPARSTGPALFVGGWAIGQLWLFWVAPLLGGVLGGVIYRVLSPEPTGVVEGVKAR
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.