PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_ROSDO
Sequence: MSDALKPLIGAAADRALSRAEAEDAFRILFEGEATPSQIGGFLMALRTRGETVAEYAAAASVMRAKCNAVKAPAGAMDIVGTGGDGKGTLNISTATAFVVAGAGVVVAKHGNRNLSSKSGAADALSQMGLNVMVGPEVVERALAEAGIGFMMAPMHHPAIAHVMPTRAELGTRTIFNILGPLTNPAGVKRQLTGAFSRDLIRPMAQTLGALGSEKAWLVHGSDGTDELTITGVSWVAALGPDGSVTDMEIHPEDAGLPVHPFEAIVGGTPAQNAADFKALLAGEASAYRDAVLLNAAAALVVADAASTLQDGVEMAATSIDSGAAARKIEAVAQITQAT
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: KTU_DROPE
Sequence: MSTAAGSRKKHSKLHNEERADITKDEFEAIREALSKEEFRKLFFDYVEEVQDPENRKIYEQEITQLEKERGVDIKFVHPKPGFVVKTSIDGELKCFINIASSPEVARPNSEVGMNPETGGRGLSWSIPMAQTGGRDDCDAKNNHCKVFDVVFHPDALHLSTRDSQFRKALIDTALDAVEREYEVALDRANLKYPKLDYKGIARPTVIRKLAANPTPEEQEPHPLEHMYPTKPPASNSEPKILPMKTKAAPVPEFAVPKYSIKQSHDVDLSEYTDELDAKLHVTVPRSLVVEIELPLLRSTAECQLDVTAKSVYLLSERLGAKYRLKLDLPFVVDDKAGNARFDTEKRRLSITLPVVRKSVNQQRQMHDTLRYLSREDSGVELHSNSESPVEDDADGDMPETPELETAAPPDPPALTPSTFLKDSVHYQLPKFDCNALDNAMAFVLDVAHVQPDSIVTLKTDRSVSVKFATIGSGYYPTHYAFYMELPSVDMEEYHKDHCIESIEAEAWDNNVIMKLFLGAESKAPTSYLAGLHANGLKEYQVYGHYKAKTDKNNECEPNPPRVVQIMRTDDAVVITVRPPHTSITTEEDDEQQQQLHKKPSKKQRKRNKKQRSYSESACEEMLDQQDGPLGRKKDATTPMVPQRKQRSYSECNDSTIGSENVNRGILKRFSRYGPRPSMSDSCSSIDDCGFSSHSCSVDASSSLFSQSFNGIPEEDRTEEGLSESCKKTVRFNDQIMKQVFRHDSSILGQRKKNQKRRNCKLRAQQRRLSEGDSADYEETRDTALKQQGEPSGNKLHDSGLDLTGASASHRTDNNSKSYRTRQDHADADAKNDAMMFEMDDEDDEI
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog, PP1-interacting protein 20.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_DICT6
Sequence: MSKERTRCREKVLQLLFQKDLGQEVEVDFSDFSPQGQAFAYRLYDGALQYKDLADSIISRFSKNWKLERMGALERNILRLAIAEMFTFSDIPQAVTVNEAVELAKKYVSPEAGRFVNGILRNIVRNWEEVKSLKEGFVDVTPEN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RNZ_CLOP1
Sequence: MLNVILLGTGGGMPMPNRFLSSVVMNFKGRKILLDCGEGTQVTMRVNGTGFKSIDIICISHLHGDHIYGLPGLLSTIGNSGRVEDIYIIGPKGIKEVIEGFLITLPYLPYKLNILEDASNLEFMVKKEKMELVEEDEKISSDLSIKTLELDHSSPCLGYSFNIRRGRKFNLEKALMNKVPKEVWSKLQRNEEVSLNGVKYYSYMVLGDERKGIKLSYTTDTRPTEDIPGFIKESDLYICEGTYGSEEDMHKAIKNKHMTFKEAANLAKRGQVKELLLTHFSPAINDPKEFINNAREAFENSHVGSDGEERVLNFKK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: Y232_RICPR
Sequence: MKKKLALLLLPFILISCNGLGSKSVKNIVDLTPKLVIQTNEPIYLDSNTKIYPFNVNMLKNKQYSPAKSKMIAEPVFIGDMIYTLDIRANISAFSIEKNKIIWSYNLSKHKKDNYIGGGILHHNGKLYITYGARLLIVLDAKSGYEIIRKELPDIIRIKPIALNDHTILVQTISNQTIALDSETLKTLWDHESIAEILSTSYSMIPIVQHDNVIVTYNTGQVLALNIKNGEVKWNFEFTNLNDHTAIPNFDTSSILCTPVHDSMNLYIATGLGKLIKLNLLTGSVLWQINADDIQSMSLIGNSLFIINNARQIAALNPETGKVKFVADLNYEKNDKRLKSTTFLVPFVGVDNNNQRSLNVISVDGILYNFNIDSNGLKMNPHIIKIIKNIRYYGLRSNNTLYFSTDRQVIFGSQI
What are the official names of this protein?
Uncharacterized protein RP232.
Protein: LIPB_STRCO
Sequence: MSELRFVRMGFGADRVEYQEAWDEQRRVHAARFVDEVPDTVLLLEHPPVYTAGRRTEDSERPLDGTPVIDVDRGGKITWHGPGQLVGYPIQKLPRPVDVVAHVRRLEEALIRTCAEFGLETSRVEGRSGVWVLGDPVEQRPVLGGLSLDFDPRLSDDEFDPRLNGPEYAPSNAGQRREDRKIAAIGIRVAKGVTMHGFALNVNPDNKWFDKIIPCGIRDAGVASLANELGRDVTIEEVLPVAERHLRDVLENAELKPRVIEKTPA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_PSEAB
Sequence: MSSPLSQAFAQNFLGHSPRWYKLTVLAFLLLNPLLLWLAGPVTSAWVLVGEFIFTLAMALKCYPLQPGGLLVLEALLLGLATPEALYAELQHNFPVLLLLMFMVAGIYFMKDLLLLLFSRLLLGVRSKALLSLLFCLLAALLSAFLDALTVTAVVISVAVAFFAVYHRVASGQRASEDYDPATDRQVPELHRAHLEEFRAFLRSLLMHAAVGTALGGVCTLVGEPQNLLIGHEAGWHFVEFFRQVAPVSMPVLAAGLLTCVLLEKSRRFGYGAQLPAAVRQVLAEYAASESRKRGAQQKAALLVQALAALVLIVGLALHVAEVGLIGLLVIVLITAFTGVTDEHQIGRAFQEALPFTALLVVFFAVVAVIHQQHLFTPIIQAVLALPAERQPGMLFIANGLLSAISDNVFVATIYITEVKQALDAGHMSREHFDTLAVAINTGTNLPSVATPNGQAAFLFLLTSSIAPLVRLSYGRMVWMALPYTLVMGGLGWWAVSHWL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYQ_XANOR
Sequence: MSETLATDATTPAEKKDFIRQIVREDLASGKHTVIRTRFPPEPNGYLHIGHAKAICLDFGLAAEFGGLCNLRLDDTNPAKEDPEFAAAIQDDVRWLGYDWAQLRHASDYFEVYYLAAQKLIRDGHAFVCDLSAEQVRQYRGTLTEPGRHSPFRERSVEENLDLFQRMRAGEFPDGARTLRAKIDMASGNINLRDPALYRIKHVEHQNTGNAWPIYPMYDFAHSLGDAVEGITHSLCTLEFEDHRPLYDWCVDKVDLVGHPELLQPLLDKGLPREAAKPRQIEFSRLNINYTVMSKRKLTALVEEQLVDGWDDPRMYTLQGLRRRGYTPAAMRLFVERVGISKQNSLIDFSVLEGCLREDLDAAAARRMAVIDPLKLVLTNLPEGHTETLQFSNHPKDESFGTREVPFARVLWIEREDFAEVPPKGWKRLVPGGEIRLRGAGIARVDEVIKNADGDIVALRGWLDPESRPGMEGANRKVKGTIHWVSAAHAVEAEIRLYDRLFSVEKPDDESEGKTYRDYLNPESKRNVRGYVEPSAALAAPEQAFQFERTGYFVADSRDHSASTPVFNRSVTLRDAWAK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBDI_LACLA
Sequence: MEAVHDFYPILFLVILFIVLYIAIKTGVFAHFKETFRLQNLLWLLGFVIVGYILGNIAHYLYLRFVPALDTIVENEATNNFVDSFLPTWFVYILMVVIAPIYEELMFREYFYRFFSHKWLAYILSILLFTLIHTRLTWSFFEYLPMSVIVTSTFHRYKRVSDSIIVHGGYNLMVLIFHIII
What are the official names of this protein?
UPF0177 protein YbdI.
What is the protein family that this protein belongs to?
Belongs to the UPF0177 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOXG1_MOUSE
Sequence: MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPPPPAPQPPPPPPQQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLPPSTALDGAKADALGAKGEPGGGPAELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
What is the function of this protein?
Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
What are the official names of this protein?
Forkhead box protein G1, FoxG1, Brain factor 1, BF-1, BF1, Forkhead-related protein FKHL1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXD_RICRS
Sequence: MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIEDIAIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKNFTGEANPNTVLLHAQNSYFAYGKLIDFFYAPIKSYPTKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRGVNIGRNARIEQHVSINYAIIGDDVVILAGAKIGQDGFGFSTEKGVHHKIFHIGIVKIGNNVEIGANTTIDRGSLQDTIIKDLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCALGGQVGIAGHLNIGDGAQVAAQGGVAQNIEAGKIVGGSPAIPIMDWHRQSIIMKQLLKTSNSKLKK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PETL_CUSGR
Sequence: MPTITSYFCLLLAALTLTLALFIGLSKRQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex (By similarity).
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Single- pass membrane protein.
Protein: METK_SALPA
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_CUPTR
Sequence: MATRLANVPQREAGTILERKEQALKPPAMFKVVLLNDDYTPMEFVVMILQQYFSRDRETATQIMLTVHREGKGVCGIYTRDIAATKVELVSTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: KA169_BUTPA
Sequence: GLIDVRCYASRECWEPCRKVTGSGQAKCQNNQCRCY
What is the function of this protein?
Poorly competes with (125)I-kaliotoxin binding on rat brain synaptosome (IC(50)>100 nM).  Is a poor Kv1. 3/KCNA3 ligand (PubMed:23523531).  May have as real target KCa1. 1/KCNMA1 channel (By similarity).  Shows weak toxicity on mice (PubMed:23523531).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 16.9, Toxin BoP2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 16 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CWC22_YEAST
Sequence: MSTATIQDEDIKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNVVDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKDYVSCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKICGWKLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSGSQGLFILDPTSYTVHTHSYIVSDEDEANKELGNFEKCENFNELTMAFDTLRQKLLINNTSDTNEGSNSQLQIYDMTSTNDVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKSVVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIEDYETDQLRILGKFWGHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLFQELVNELGLDELQLRLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLLTEDMRSRLTIIQEVEDAEEEEKKLREEEELEKLRKKARESQPTQGPKIHESRLFLQKDTRENSRSRSPFTVETRKRARSRTPPRGSRNHRNRSRTPPARRQRHR
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22, Complexed with CEF1 protein 22.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1967_RHILW
Sequence: MSKPPSDPPRRPPAAFTYEDEATERHDNGRQAERRRKPESFSENIVVTADEDDPFLNPDKDLSAVPVATPLRRRTSFGKIAAGAFGILLSLGIGLWTDSLIRDLFTRADWLGYLALAVLAVGVLAVLALVIRETSGMMRLAAVQAIKAEAEAAMVETRPAKARAVVARLVTLLSANPETSKGRATLKATEGEVIDPPHLIALAERELLTPLDRKARALIVNASKRVSLVTAVSPRAVVDLLYVLYEAVRLIRAMAELYGGRPGTLGMFRLLRDVLAHLAVTGSIAVGDSLVQQVLGHGLASKLSARLGEGVINGLMTARIGIAAMDLCRPLAFHALKRPGIGDFIGDLTPSMSPRGNTP
What are the official names of this protein?
UPF0283 membrane protein Rleg2_1967.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAI1_HUMAN
Sequence: MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDAELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRRQHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
What is the function of this protein?
Part of the dynein complex of respiratory cilia.
What are the official names of this protein?
Dynein axonemal intermediate chain 1, Axonemal dynein intermediate chain 1.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Dynein axonemal particle. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: NUOB_THISH
Sequence: MGIEGVLEKGFVTTSADKLINWARTGSLWPMTFGLACCAVEMMHAGASRYDLDRFGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYAVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQNKIRRTNTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: METE_HAEIN
Sequence: MTTSHILGFPRVGAKRELKFAQERYWRKELAEQDLLDLAKALREKNWKHQAAANADFVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLTLDQYFQLARGNKDQFAIEMTKWFDTNYHYLVPEFQKSTAFKANPAHYVNQIREAKALGLNFKPVIVGPLTFLWLGKEKGEAFNRFDLLNQLVPVYVEILNALVAEGAEWIQIDEPALALDLPAEWVEAYKSVYTELSKVNAKLLLATYFGSVAEHAELLKALPVAGLHLDLVRAPEQLAAFEDYSKVLSAGVIEGRNIWRANLNKVLDVLEPLKAKLGERLWIAPSCSLLHTPFDLEVEVQLKEKNTALYSWLSFTLQKVEELNVLKQALNNGRASVQAALDASQVAADARATSKEIHRPEVAERLANLPKGADQRKSPFAERIVKQNAWLNLPLLPTTNIGSFPQTTEIRHARASFKKGELSLADYEAAMKKEIEYVVRRQEELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVTRPEPMTVRWSQYAQSLTNRVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVLDLEAAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGVQDDTQIHTHMCYSEFNDILPAIAALDADVITIETSRSDMELLTAFADFKYPNDIGPGVYDIHSPRVPTATEVEHLLRKALNVIPKERLWVNPDCGLKTRGWTETIDQLKVMVDVTKKLRAELA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: NANA_SHIF8
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CLOBH
Sequence: MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKVKFIQNFTDIDDKMIKRANEEGSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEIIKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEELQLGARINVDERKKDPMDFAIWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQSEARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQINFSMELLDSTKAALDRLYNSINNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDDDFNTADAISIIFDLIRDVNTNVTIESSKELVKYTLDLIRELGSPLGILQESTKASLEEEIEKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGIRWKQI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_TRIV2
Sequence: MTKTIVVKIGTSSLTQPETGQLALSTIATLAETLSYLRQQGNQVILVSSGAVGVGCARLGLTERPKAIALKQAVAAVGQGRLMRVYDDLFTTLQQPIAQVLLTRSDLVQRSRYLNVYNTFRELLALGVIPVVNENDTVAVDELKFGDNDTLSALVASLVEADWLFLLTDVDRLYSADPRSVPDARPISLVTSIKELADLQVQTGSQGSQWGTGGMMTKISAARIAIAAGVRTVITQGRYPRNIEKIIQGELIGTHFQPQPEPTSARKRWIAYGLVPTGKLYLDSGAIAAIVKAGKSLLPAGVKTVAGEFEPQDAVQLLDPQGNEIARGLVNYSSKDLQQICGRHSKEISTILGYVGAETVIHRDNLVLT
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_STRP6
Sequence: MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEYEFVTSLKEDTPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHIESPGKTVEVNGETFKEYYGSASAYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: AROL_YERPG
Sequence: MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVVATGGGAVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLVVEQILQMLTGEMVK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_BORA1
Sequence: MGNAMLAEPRTLTKAELAELLFERVGLNKREAKDIVDTFFEEIREALARGDSVKLSGFGNFQVRDKPPRPGRNPKTGETIPIAARRVVTFHASQKLKSTVEQSGNPAEVSDDEAAE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MINE_PROM3
Sequence: MATTLRDILDKLLGRQPASAKTARERLQLVLAHDRSDLSPELLDQMRREIFEVVAKYVEIDIEGGDVSLETEDRMTALVANLPIKRSQAKAVSNQAKAVSNQEKAVSSQEKVSNSQESVSTPEAME
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: TLR21_CHICK
Sequence: MFNQSKQKPTMKLMWQAWLIYTALAAHLPEEQALRQACLSCDATQSCNCSFMGLDFIPPGLTGKITVLNLAHNRIKLIRTHDLQKAVNLRTLLLQSNQISSIDEDSFGSQGKLELLDLSNNSLAHLSPVWFGPLFSLQHLRIQGNSYSDLGESSPFSSLRNLSSLHLGNPQFSIIRQGNFEGIVFLNTLRIDGDNLSQYEPGSLKSIRKINHMIISIRRIDVFSAVIRDLLHSAIWLEVREIKLDIENEKLVQNSTLPLTIQKLTFTGASFTDKYISQIAVLLKEIRSLRELEAIDCVLEGKGAWDMTEIARSKQSSIETLSITNMTILDFYLFFDLEGIETQVGKLKRLSIASSKVFMVPCRLARYFSSLLYLDFHDNLLVNNRLGETICEDAWPSLQTLNLSKNSLKSLKQAARYISNLHKLINLDISENNFGEIPDMCEWPENLKYLNLSSTQIPKLTTCIPSTLEVLDVSANNLQDFGLQLPFLKELYLTKNHLKTLPEATDIPNLVAMSISRNKLNSFSKEEFESFKQMELLDASANNFICSCEFLSFIHHEAGIAQVLVGWPESYICDSPLTVRGAQVGSVQLSLMECHRSLLVSLICTLVFLFILILVVVGYKYHAVWYMRMTWAWLQAKRKPKRAPTKDICYDAFVSYSENDSNWVENIMVQQLEQACPPFRLCLHKRDFVPGKWIVDNIIDSIEKSHKTLFVLSEHFVQSEWCKYELDFSHFRLFDENNDVAILILLEPIQSQAIPKRFCKLRKIMNTKTYLEWPPDEEQQQMFWENLKAALKS
What is the function of this protein?
Participates in the innate immune response to microbial agents.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  Does not respond to LPS and responds with less ability than TLR2-2 to mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2).
What are the official names of this protein?
Toll-like receptor 2 type-1.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CR11_RANGI
Sequence: GLLSVLGSVAKHVLPHVVPVIAEHL
What is the function of this protein?
Antibacterial and antiviral peptides that adopt an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-1.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.