PharMolix/UniProtQA huggingface dataset:
Protein: TX335_LYCSI
Sequence: MKSVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAAGKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1k, Toxin-like structure LSTX-B35.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_CYAP4
Sequence: MTSIRIGNGYDIHRLVSDRPLILGGVNIPHELGLLGHSDADVLTHAIMDALLGALSLGDIGHYFPPGDPQWAGADSLKLLAQVHQLVQERGWQVGNIDSVIVAERPKLKPHLAAMRDRLSAVLKVKPDQIGIKATTNEKLGPEGREEGICAYAVAVLVSVA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RR15_NICTO
Sequence: MVKNSVISVISQEEKRGSVEFQVFNFTNKIRRLTSHLELHKKDYLSQRGLKKILGKRQRLLAYLSKKNRVRYKELINQLDIRETKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DUX4C_HUMAN
Sequence: MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASAASTDASHPGASQPLQEPGRSSTVTSSLLYELL
What is the function of this protein?
May be involved in transcriptional regulation (By similarity).  Down-regulates MYOD1 expression and may up-regulate MYF5 expression.  May regulate microRNA (miRNA) transcription, up-regulating the expression of some myogenic miRNAs, including MIR1-1, MIR133A2, MIR133B and MIR206.  Impairs the differentiation of myoblasts and may be involved in muscle regeneration.
What are the official names of this protein?
Double homeobox protein 4C, Double homeobox protein 4, centromeric, DUX4c, Double homeobox protein 4-like protein 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_STAAW
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GCY6_CAEEL
Sequence: MIGVYLRSVIFPLLFVIQTICQPPGNVFHLGFLHCDVLENNVEGSTTYINYRTSASAASIAIDKIKREGLLLGYDFKFTILYDQCDENIAAGNAIKLFAEHNVDVLFGPTTNNAAMPVFILATYYNIPLITWGITSSATLDDESRFPTAGMLSIGSRSLAVTFREVMKEYGWDQFVFAYSLEMNDEKCETLRDDFQNMVAYYGDIVLSYAVQIMDHSEEGLLAILKDVSTRGRIIVPCFHEGNSRGLHRRWMLVAARNGFVNDEYVYIFPSLRSRGYAVPQADGTFRYPWTEATGPQPGDQEALLGFQKSIFIVDMQGQGNVGSNYTQFEHEIIQRMKEPPYNCTDACASPEYQTAATYAGQLHDSVYIYGVVMDQIMKTVPNQYKNGTAFPRKMAGVFNGVGGTVAIDEGGGLQPTLFVLTLDSNNNSSLIMTVDVDQQEAVVTKHYTNEATALWSHRKGIRPPDQPICGYTGSLCPANVFFQYIGWFIAAIIIIFFTIMGAILAFIYLCHAKQQEVERQNALWQIPFKSMMTVTKKGKGEHSMRSISSVPSTISSTRSSTLSEVGETRNYLFFQIQNDVEMERVAAKKHSIRMVFDNKTCATMRQMRLIDHANLNKFIGMSLDAPQLYSVWRFCSRGSLADVIRKASMQMDGFFIYSLMKDIINGLTWIHESSHEFHGMLTSKNCLLNDRWQLKITDFGLRIFRTHDQYNKSDRLWTSPELLRTDDILGSREGDIYSFGIISAELITRSSVFDLENRKEDAEEIIYMLKKGGLQSPRPSLEHDESIEINPALLHLVRDCWTERPSERPDIKQVASQLRSMNTNRNDNLMDHVFNVLESYASTLEDEVAERMKELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEPETFDIVTLFFSDVVSFTTLAGKCTPLQVVNLLNGLYTIFDGIIEQHDVYKVETIGDGYFVASGVPRRNGNEHTRNIASMSINFVKSLADFSIPHLPGEKIKIRVGFHCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNSKPGQIHLSEEANQMLMRLGGFTTEPRGEVIIKGKGVMATYWLLKMDESAAPKILKKKQD
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Regulates chemotaxis responses toward the salt ion Mg(2+) and to a lesser extent toward Cl(1-) in ASE left (ASEL) sensory neuron (PubMed:19523832).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-6.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HAT2_ARATH
Sequence: MMMGKEDLGLSLSLGFSQNHNPLQMNLNPNSSLSNNLQRLPWNQTFDPTSDLRKIDVNSFPSTVNCEEDTGVSSPNSTISSTISGKRSEREGISGTGVGSGDDHDEITPDRGYSRGTSDEEEDGGETSRKKLRLSKDQSAFLEETFKEHNTLNPKQKLALAKKLNLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTEENRRLQKEAMELRTLKLSPQFYGQMTPPTTLIMCPSCERVGGPSSSNHHHNHRPVSINPWVACAGQVAHGLNFEALRPRS
What is the function of this protein?
Probable transcription factor that plays a role in auxin-mediated morphogenesis.  Negatively regulates lateral root elongation.
What are the official names of this protein?
Homeobox-leucine zipper protein HAT2, Homeodomain-leucine zipper protein HAT2, HD-ZIP protein 2.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSRD_YERPP
Sequence: MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGIVFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQTLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIYEWLQRRRSRKASA
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPGG_ECOUT
Sequence: MKHKLQMMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FPG_ECOLU
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PAN_METJA
Sequence: MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKELERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSELVKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAVEKIMEKKKVKVKEPAHLDVLYR
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.  In addition to ATP, is able to cleave other nucleotide triphosphates such as CTP, GTP and UTP, but hydrolysis of these other nucleotides is less effective in promoting proteolysis than ATP.  Moreover, PAN by itself can function as a chaperone in vitro.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_STAAC
Sequence: MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNHVFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTLNVPLFVNEGDVLIINTGDGSYISRG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1662_STRPI
Sequence: MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLESFYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHVFITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSSEFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLSQPQGLVFVKEV
What are the official names of this protein?
UPF0246 protein SPH_1662.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CYC6_NEOTN
Sequence: ADLDNGEKVFSANCAACHAGGNNAIMPDKTLKKDVLEANSMNTIDAITYQVQNGKNAMPAFGGRLVDEDIEDAANYVLSQSEKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: HPRT_METOI
Sequence: MNLLEDTLKSCPIVKRGEYNYFIHPITDGVPLMNSQLLREVATKIIKISDMDIDKIVTAEAMGIPIATTISLYTDIPYVIMRKRKYLLEGEIPVHQETGYSKGELYLNGVNKGDKVLIVDDVISTGGTMVAIIKALEKAGAHIKDIVCVIERGNGKEEVKEKTGYDVKTLVKIDVVNGKVVIL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y756_RICPR
Sequence: MPIVTVTLNNKSFQLYCNNGDEEKVLSLADKLNDKIAEIKLSSPTASFDLLLVMASLNAQAEIAILTEKLYKNGFQNNNHEEEKFAETLTTIASYLENLARKMEK
What are the official names of this protein?
Uncharacterized protein RP756.
Protein: FPG_CELJU
Sequence: MPELPEVETTLRGVSPHILGRKVTDLVIRQPRLRWPIPLELSEQLPGQQLKAASRRGKYLLLSFNTGTALIHLGMSGSLRIVKPEEPPLFHDHFDMHFGNRILRYCDPRRFGCLLWEAGDIHQHALLRDLGPEPLGDDFTPAYLYERSRKRTQAIKQFIMDSKIVVGVGNIYANESLFMAGIKPIRKAGALSRHMCEDLVRDIRFVLQRSITQGGTTLRDFVGGDGKPGYFQQQLLVYGRGGEACKTCQKPLKEIRMNDRTTVYCVTCQQ
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS14_AZOC5
Sequence: MAKKSAIETNERRRKLSQSKAAKRASLKAIVNDKTLPIEERFAATLKLAQMPRNSAKIRVRNRCEVTGRPRAFYRKLKMSRVALRELGSQGLVPGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CATNT_GEOSL
Sequence: MDHRLLSFISAPLPSLIASLARHGGFGAWFVGGCVRDALLARPSNDIDIVVGPGGEDLPRAVAARIGGSFFPLDEERGHARVVLKGEGASCDFAPLQGGTIAADLALRDFTINALAVSCGSDDLLDPLGGAADLAQRVIRACSAGAFAADPLRIVRAYRFAAHLDFEIHAATLALIPDHAPLLATVAGERIRDELFRMLDLPHAVPYVLKMSCAGVTGAIFGADDLPADTAAGALDRVESLCRDLSAFGTEAEPVRARLRQEVQPGITIRALAKLAAFLNGAGIPAGIASQRLMLGKAATRLLELLCSSARLTWPAPAAAPDPHALFTLFCHREPAGCEQLILPLAEGILPEDRCRHLAAYLTRQHIPRGGRLLLTGDDIMILLGLPPGRQVGEAIELLRAAQSTGEVRTRAEAQRYLAKKQLTTPEPLR
What is the function of this protein?
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus.  Adds the two cytidine residues to tRNA.
What are the official names of this protein?
CC-adding tRNA nucleotidyltransferase, C-adding TNT, CC-adding enzyme, NTSFII.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Protein: ORN_CHRVO
Sequence: MAQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDDWNKNTHGKSGLIEKVKNSTVSEAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWMPKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEALADILESIEEMRYYREHFLKV
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_LACAC
Sequence: MAKTIVHENESIDDALRRFKRSVSRSGTLQEYRKREFYEKPSVRRKLKSEAARKRRHY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SYT_CELJU
Sequence: MPVITLPDGSQRSFDKPVSVYEVAASIGPGLAKATLGGRVNGQRVDAHDLISEDANLVIFTPKDDDGLEIIRHSCAHLLGHAIKQLYPDVKMAIGPTIDNGFYYDVDLEHKLTDEDIAALEARMLELAKTEYDVVKKKVSWQEAHAVFAARGESYKLEILERDIPQSDQPGLYHHEEYIDMCRGPHVPNMRFCLNFKLMRVSGAYWRGDSNNKMLQRIYGTAFADAKQLKAYLNLLEEAAKRDHRKLAKKFDLFHLQDEAPGMVFWHPKGWTLWQQIEQYMRAKQNDWGYQEVRTPLIMDRVLWEKSGHWENYRENMFTTESEKRDFAVKPMNCPGHVQIFNHGLRSHKDLPLRLAEFGSCHRNEASGALHGIMRVRGFVQDDAHIFCTEDQVVAEVAAFNQMLKSVYDDFGFTDIAVKLSLRPEKYAGSLETWNKAEEGLRTALRAAGLEWEELPGEGAFYGPKIEYQIKDALGRSWQCGTIQLDYVLPERLDAEYVADDNVRKRPVMLHRAILGSFERFLGILIEHYEGSFPVWLSPVQVVVANITDSQAEYVKRVEKALREQGIRVIADLRNEKIGFKIREHTIQRVPYLLVVGDKEVENQSLAVRTRDGKDLGVMPLDAFIAHLTADIARRGRVFSAE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_STRA3
Sequence: MSNYAIILAAGKGTRMKSDLPKVMHKVSGITMLEHVFRSVQAIEPSKIVTVIGHKAELVRDVLGDKSEFVMQTEQLGTGHAVMMAEEELATSKGHTLVIAGDTPLITGESLKNLIGFHVNHKNVATILTADAANPFGYGRIIRNSDDEVTKIVEQKDANDFEQQVKEINTGTYVFDNQSLFEALKDINTNNAQGEYYLTDVIGIFKEAGKKVGAYKLRDFDESLGVNDRVALATAEKVMRHRIARQHMVNGVTVVNPDSAYIDIDVEIGEESVIEPNVTLKGQTKIGKGTLLTNGSYLVDAQVGNDVTITNSMVEESIISDGVTVGPYAHIRPGTSLAKGVHIGNFVEVKGSQIGENTKAGHLTYIGNAEVGCDVNFGAGTITVNYDGQNKFKTEIGSNVFIGSNSTLIAPLEIGDNALTAAGSTITDNVPIDSIAIGRGRQVNKEGYANKKPHHPSQK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP07_VACCC
Sequence: MVFQLVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNECCRLKLSTQIEPQRNLTVQPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: ATP8_STRCA
Sequence: MPQLNPNPWLFIMFMSWTVFLFLMQPKLTSFISTNSPSNKNKTTLTPTPWTWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: GCK_SULTO
Sequence: MDKIIEKILTFSDPYIALDERVVIKKNEIIVDGNHFPYTKPAIIAVGKASYKMAKFFIDKLKDVKGLVILPKGSYISLPKVEVIESTHPDISELSFKAGTEVIKFLKNEDYDLLIFLLSGGASALMEYSNVPYEILRDINEKLVKSGLSVNEINIVRKHLSLIKGGKLTEFSKAPILTLIVSDVPGGDLSAVGSGPTLPDSSTVDDAKLILNKVGLGEYSKYLIETKKEVHNSFNFLILDINIVLRKLRDIVQNPIILSSEIRGDAYSFGQNLAGIVNTSFSNLGLKPPYTLLAGGEPDVKIEGKAGKGGRNGEVCLGFLKWVKRNSNHRFKLYAIATDGIDGNSEYAGCIVDENTIVDNIEYYIYSHSSYEALEKVGRVIKTGYTFTNVNNVYVLEVT
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate.  It can also utilize GTP, CTP, UTP, ADP, AMP or pyrophosphate as phosphate donor.
What are the official names of this protein?
Glycerate 2-kinase, GCK, 2-phosphoglycerate forming glycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-1 family.
Protein: RS10_PYRIL
Sequence: MSLAARRKVRIRLYGTNPADVEQVAREIVDLAKKMGVQVKGPIPLPTRRLVVTVRRAPSGQGYHTFDHWELRISKRLIDIEASERVLRRLMTIRVPDTVKIELQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNLJ_XYLF2
Sequence: MIPLDPAQRAAELRRRLQEANYHYHVLDQPRIPDADYDRMLRELDALEATYPDLATPDSPTQRVGHTIATAFSEVRHTVPMLSLNNAFSDPEVLEFVRRITARLGETAPGFSAEPKLDGLAISLRYQNGIFIQGATRGDGVTGEDVTANLRTLPTIPQRLQSDTWPTVLEVRGEVYMPRPDFEAYNTQARLRGWKVLANPRNGAAGSLRQLDPHITAQRPLSFYAYGIGEVTDDVAFHRHSEILASLRAWGFPVSPLVELVYGSEGLLNYYRRMETIRDTLPFDIDGIVYKLDDLSGQHEMGFVARAPRWAIAHKFPAQEQTTTVEAIEIQIGRTGAATPVARLTPVQVAGVTVTSVTLHNADQIARLDVRIGDTVIVRRAGDVIPEVVAVITDSRPPGATAWSMPMACPVCGSEIVRETGAAVWRCSGELACPAQRKEAIRHFVSRRAMDVEGLGVKCIELLVDAAVVHGVADLYHLSLDQLLRLRLVTNAQTPTMLLREARDHVTGMRYQQLEEILRTVGVDLSGEGDVPKHWQIDVLRAQWPDFDWNHKKIATKWAQNLIAAIDRSRQTTLERFLFALGMTHVGETTAKALAHSFGDLAIIRQLPWPLFKCVPDIGGEVARAIGHFMDQPANQQAIDDLVERGVRITDAHPPTSTLRDQLTLASLLEHLEIPKITPLRAVQLATLAPTLPLLAEADLDALLQAGVPQPAAQSLTEWFQSPDNISLARRLQHCCDVLLAQLLSPDRAHTAPLNGQSVVLTGKLASLTREAAATRLESLGAKIVGSVSKKTSFLVAGEDPGSKLDKAHALHVDIWDEARLLAFLEQYSAQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.