PharMolix/UniProtQA huggingface dataset:
Protein: RS13_GLOVI
Sequence: MARIAGVDIPREKRVEIALTYIFGIGPSRATQILLSTGINPNLRVRELTDVQVSLLREEIEQKYQVEGDLRRFENINIKRLMDIGCLRGRRHRLGLPVRGQRTRTNARTRRGGRKTVAGKKKAAAKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ATP6_ACTP7
Sequence: MAGTTAEYISHHLSFLASGDGFWAVHLDTLFFSLLAGVIFLFVFSRVAKNATSGVPGKLQCFVEIVIGWVDGLVKDNFHGPRNVIAPLALTIFCWVFIMNAIDLVPVDFLPQLANMFGIHYLRAVPTADISATLGMSICVFFLILFYTVKSKGFGGLVKEYTLHPFNHWVFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYMADNFALQALGIPLHLVWAIFHILVITLQAFIFMMLTIVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACCA_KLEP3
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPRRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIVAPRLKELKLIDSIVQEPLGGAHRNPEAMAASLKAQLLADLADLDLLSEEELLNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORC3_SPECI
Sequence: MATSSVSKGCFVFKPNFKKRKISVPIEDYFNKGKNESEDSKLRFETYHLMWEQMKCETERLQEELNKNLFDSLIEFLQKSHTGFKKNSGDWGHQIKHREIPVAALVLGVNVTDHDLIFRSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMACCVDAKPKEKESIQVTQKMTHCSMDPLSSWYMTVTQKTHPKISGKKRTTSSKWQSPPVVLILKDMESFTTKILQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLPCKEHLTTVLDKLLLTAQFPFKISEKVLQILTNIFLYHDFSIQNFVKGLQLSLLEHFYSQPLSVLCCSLPEAKRRINFLSAHQCENIRRLPSFRRYVEKQVSEKQVALLTNERFLKEETQSLLENLHVYHTNYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASALQLLRMLARDDLMTILQKCFKVFKSSSEKQLGSTAKRIEEFLAQFQSLDADAKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRTSKKQTRFEVLREKVVNFIDCLVREYLLPPETQPLHEVVYFSAAHTLREHLNAAPRIALHTALNDPYFYIKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMESNSATTEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the ORC3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y467_MYCGE
Sequence: MKKGNKTVWNECIDILDNVKSPSFSANFDDYFKKSKSKPPKKNKKVLNNIKKAELKLKKKANKKQKANTLYIPPFAQQAKGIVITINKMWKNVHNDDSKQEISILSDVSLQIAYGEIVIILGSSGSGKTTLLNLIGGYDSISLGSCIVANCPLEKCTSEQLLTYRKNNLGYVYQRYNLIELLSAYDNIAISQNLIPKYQRRLDIEELAEKLDIKEILYKFPYEMSGGQKQRVAIARAIIKEPKLLLCDEPTGALDSNSAENIINLLQTINKTYKQTILMVTHDVSLTRIANRIIKISDGKIVSNQLVRPLV
What are the official names of this protein?
Putative ABC transporter ATP-binding protein MG467.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: AMO_PINMG
Sequence: MSLPKTANGMDKLKLCYLLLFYLGSSSLTEVSGAQTCEIDSVLCTSDLSEPDDPPIFHDLTTKEIKSVQTYLYHQRDLRLLRPGLAKINTSFIQGMELYLPNKKDVIHYLQSKVPTPKPPRAAVVTIFRGDCDPAVVEEYIVFPLPWPTQHRLHRKVPYYLRPFNDVEFATISDFLTKQVDGVLRQFLEESFGGRLINCGNRCLNFQFASPVGPSVSNEPGARKSWYWLHQLVEYSALHPVDFAVLMKIVGCVYTIEKVYFNNMYFNSLQEVALHYRNPSFPRLRIPYPVDSKQLFSKMERRGILFPEKPVSPPRQVEPEGKRYSVKYQEVKYMNWKFNFRLSPGLGPRLHNIRYHDRLIVYELALQDIVVFYSGAEPPHQYANFFDSSYMIGMNLQGMVPGVDCPTGATFIDSHILTESSLKPAKLINAFCVFEQNTGDFLRRHISKTSPDGPFYEGVPSIVLVLRAITTIANYDYTIDFIFHHNGVLQTKVVPTGYILPSLYTKQNENKYGFRLNNKLIGNLHHHLFNFKVDIDINGQHNRYETLDIVLDKTSHPVSKKPYDVWYQNKIKHNLRKTEMEALFKYDFDKPMHHIFYNNNLKSPEGNNMAYRLVNRGMSKSLLPECSGNEGTGAWMRHQIAVTKRKETELTSSSVYSAFGTKNPVVNFRNFYADNENIVDEDLVAWVTMGTYHIPHTEDLPVTHTPGLDLSFFLSPFNYFPEDPAMGSRDSVRIEAVDKNNLKRGIKIDKQTFPEKMTCKAPIGNYFEYILKRPNVIFDIQ
What are the official names of this protein?
Putative amine oxidase [copper-containing].
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
Protein: RS8E_STAMF
Sequence: MAWYQGNDLRKPTGGKKTRHRKKRKHELGRPPTMTRFSVKEAQKIIRVRGGNLKIRLKRAVYVNVAVPNEGKVTKTRILEVVETPSNPQYARGNYITKGTIVRTELGLVKITSRPGQDGVLNGILLEK
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: YFEW_SALTY
Sequence: MKFTLVATVLLTFSLSAFAVEYPVLTTASPDQVGFDSQKLHRLDGWIQNQIDAGYPSINLLVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLASNTKMYATNFALQKLVYEGKIDVNDLVSKYIPGFKDMPGDKIKGKNKLRIIDILHHVAGFPADPQYPNKNVAGKLFSQSKSTTLEMIKKTPLEYQPGSKHIYSDVDYMILGFIIESITAMPLDRYVETTIYKPLGLKHTVFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTNTLWGQVHDEKAWYSMGGVSGHAGLFSDTHDMAVLMQVMLNGGGYGNVKLFDDKTVAQFTRRSPEDATFGLGWRVNGNASMTPTFGVLASPQTYGHTGWTGTLTSIDPVNHMAIVILGNRPHSPVANPKVNPNVFVSGLLPAATYGWIVDQIYGSLK
What are the official names of this protein?
Putative D-alanyl-D-alanine carboxypeptidase, DD-carboxypeptidase, DD-CPase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family. YfeW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NUOB_POLAQ
Sequence: MALEGVLKEGFVTTTADQLINWTRNGSLWPMTFGLACCAVEMMHAGASRYDLDRFGVVFRPSPRQSDLMIVAGTLCNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHNSYSVVRGCDRIVPVDIYVPGCPPTAEALIYGIIQLQSKIARTSTIARKA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ELO2_CAEEL
Sequence: MAAAQTSPAATLVDVLTKPWSLDQTDSYMSTFVPLSYKIMIGYLVTIYFGQKLMAHRKPFDLQNTLALWNFGFSLFSGIAAYKLIPELFGVFMKDGFVASYCQNENYYTDASTGFWGWAFVMSKAPELGDTMFLVLRKKPVIFMHWYHHALTFVYAVVTYSEHQAWARWSLALNLAVHTVMYFYFAVRALNIQTPRPVAKFITTIQIVQFVISCYIFGHLVFIKSADSVPGCAVSWNVLSIGGLMYISYLFLFAKFFYKAYIQKRSPTKTSKQE
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  Uses malonyl-CoA to add 2 carbons per cycle to the chain of long-chain fatty acids.  Condensing enzyme responsible for the elongation of palmitate (hexadecanoate, 16:0), also involved in polyunsaturated fatty acid (PUFA) biosynthesis.
What are the official names of this protein?
Elongation of long chain fatty acids protein 2, ELO-2, F11E6.5/ELO-2, Long-chain 3-oxoacyl-CoA synthase 2, CEELO2.
What is the protein family that this protein belongs to?
Belongs to the ELO family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECB_BUCAI
Sequence: MLEEKKKQESFEIQRIYIKDVSFEAPNTPNIFHVNWIPTIKLNLNTTTKKIKENIFEVVLMVKVTVKIKEDLVFLCDIDQAGIFFIANINEKRLKHCLYSYCPNILFPYARTCISNLVSCGSFPQMNLAPINFDALYHDHIK
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAMC_TRYBB
Sequence: MSSCKDSLSLMAMWGSIARFDPKHERSFEGPEKRLEVIMRVVDGTHVSGLLAHDDDVWQKVIDAICAHIVSREFNEYIRSYVLSESSLFVMKDRVILITCGTITLLNCVPLICEAVSTVCGEVEWVSFMHKNYSFPWEQKGPHLSMAEEFKTLRSHFPSGQPFIFGPIDSDHYFLYFHSDVVQPSCSDDAQLSMTMYGLDRNQTKHWYSDKMLPTGPETAVIREATGLSEVVDDSWILHDLQYEPCGYSINAIRGSEYQTIHITPEEHCSFASYETNTCALNYSKCICGVLRVFDPERFSVIVFIDPDSAVGKSYHSGGTIGVEPEYYPNYEAHHRTVNEYTPGHWVLKVNYVKRAVGTVGTSAASGAKE
What is the function of this protein?
In association with the catalytically inactive AdoMetDC prozyme, catalyzes the decarboxylation of S-adenosyl-L-methionine which is essential for the biosynthesis of the polyamine spermidine.  Required for growth and survival during the bloodstream life cycle stage (PubMed:18949025).
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: EASN_ASPFU
Sequence: MKKQVTFKPFRLSPVDHSLPKVYIFKSLYFRGVDDTGSLSRLQDGIDRLISCLPFLSGEVVPCADIPDKVGVLQVQMPCPSLQEIPMLLVKSYPNHTWPAASTSERWRNTALLDQSYRPLPDFIPPSKPRPVLRFQANFLADGLMLCMGYNHSVFDGTGAGNILEMLADCCRANPNSILALPTNGDIESELRGLLSSPGVAVANASQEAYAINCAHTEVEPEPSSAMLYCWPFLLSSEKIECLQEACNSLLPHIVRLYSGTQSSLINQDTNWPHILSSNDVLTALLAVSIEKAREATGALGHMSRSLAMAVNLRERLKPMPRHYLGNLVTTVWVSHHRPAVKDLETMVLPVPACNRHEIDRDDLLWITHVAFRIRLGLNAINEEHIRGLIHYLHSQDDWEQIGIHFTDPIFISSWRHLKVYELDFGPTIGHAEHFEMDVGTTDGVCVVMPANTRAVGKTKKAPWDIRIVLNPEVLQALIASAIFGWAMVKDAST
What is the function of this protein?
Fumigaclavine B O-acetyltransferase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid (PubMed:15933009, PubMed:26972831).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:15870460).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:20039019, PubMed:20526482, PubMed:21409592).  EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:20526482).  EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:20526482).  Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A (PubMed:26972831).  Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus (PubMed:19672909).
What are the official names of this protein?
Fumigaclavine B O-acetyltransferase easN, Ergot alkaloid synthesis protein N.
What is the protein family that this protein belongs to?
Belongs to the fumigaclavine B O-acetyltransferase family.
Protein: GLMM_SALTO
Sequence: MGRLFGTDGVRGRANADLTPELGLAVAVAAAHTLAEADRSHPPLAVVGRDTRASGEMLESAVVAGLTSAGANVVRVGVLPTPAVAFLTAEAKADIGVMLSASHNPMPDNGIKLFAAGGHKLPDEIEMKIEAAVEANTTTAWERPVGAGVGRVHDLLDGADHYVQHLVGTVPHRLDGIKVVVDCANGAAAEVAPAAYREAGAEVVAIHAEPNGLNINDECGSNHVAALRQAVVEHGAQLGIAHDGDADRCVAVTADGDEVDGDQVMAILALAMREAGTLTADTLVATVMSNLGLRIAMSREGIRLVETKVGDRYVLEELRASGLALGGEQSGHIVMPAHATTGDGVLTGLHLMSRMAGTGRPLAELAAVVSPLPQVLINVPVGDRTVGAAAPAVRAEVARAEAELGDAGRVLLRPSGTEPLVRVMVEAGTETTAREVAERIAEQVRTASPVS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y3545_CROS8
Sequence: MEEWFLYLIRCPDNRLYTGITTDVARRFAQHQRGKGAKALRGKGELTLVFSAPAGSRSEALRAEYRIKQLTKRQKEQLVAGELAFEAMKSAPQTP
What are the official names of this protein?
UPF0213 protein ESA_03545.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: IPI3_BPT4
Sequence: MKTYQEFIAEASVVKAKGINKDEWTYRSGNGFDPKTAPIERYLATKASDFKAFAWEGLRWRTDLNIEVDGLKFAHIEDVVASNLDSEFVKADADLRRWNLKLFSKQKGPKFVPKAGKWVIDNKLAKAVNFAGLEFAKHKSSWKGLDAMAFRKEFADVMTKGGFKAEIDTSKGKFKDANIQYAYAVANAARGNS
What is the function of this protein?
Internal protein III is one of four proteins in a complex that functions in bacteriophage head maturation.
What are the official names of this protein?
Internal protein III, IpIII.
Protein: Y4734_AZOVD
Sequence: MSTDKSPYAAFSALLASSGRDRSPAELHGQLLGRSCAGAGFEVDAWLADAADLLGGQIPDNVRQALIGLQEMVKGELTGGEVAVVLLLPSDEAPLAERAAALGQWCQGFLGGFGLAAGDRPLSAEAMEVLQDLAAISQVQSALEDSEEGEGAYMEVMEYLRVAPLLLFTECAGPVAPAPKPSVH
What are the official names of this protein?
UPF0149 protein Avin_47340.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: MUTS_LEUCK
Sequence: MGKIADTPMMVQYHEIKAQYPDAFVFYRLGDFYELFEEDAIQGAKILELTLTARNKNSENPVPMAGIPHHAAQNYIDILVDQGYKVAIVEQMEDPAVAKGMVKRDVVQLVTPGTKMADGAGGDKQNNYLAAVLPAKNVWSIAYVDLSTGELRATTTGRFEDVMDELSSLEVKEVVLSKNDVATTEQQIASQLGERGIVISAQGTAEPSATVSFLTQALKVTSEIEATTILLNYIFDTQRRSLDHIVPATSYERLKFLKFNQDTRSNLDLVENMRTKKKAGSLLGLIDRTNTAMGGRLLKQWLLKPLRESSDIEARLDLVQSFQNDFLTRGALQDHLKSVYDLERLAARAAMGTMNARELVQLKRSLRAIPGIKSVLLQADTTLSNAGQQLDDMTDLADLIDVAIVDEPPVSVREGNIINDGFDERIDGYRQVLKDNQQWLAQLEIDERAQTGINSLKVGYNKNFGYYIEVTKANIGRLATDRYQRLQTLTNAERFVTPALKQHESLIIEAQAKRTEREYELFVTVREHVKSDISRIQTLAQHIARLDVLSSLADVADNQRFVRPTFTNQHVIHIMQGRHPVVESILDAGDFVANDVILDESINMQLITGPNMAGKSTYMRELALIVILAQMGSFVPADVAELPIFDQIFTRIGANDDMAMGQSTFMVEMAEANDALQQATANSLVLFDELGRGTATYDGMALAQAIIEFLDKHIHAKTLFSTHYHELTVLADNHTSIENVHVGAVEDDEGQLHFLHQIQSGPADKSYGIHVAALAGLPKELIDNATSILHDLEAGKMIVTQTNDQVASAVIQPDAHLSEQVALFDMTVTDDKTQKILDALDNYDILNMTPVDAINALNRLKKMRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PP322_ARATH
Sequence: MALCNLNPTQGIFPLQGLSKSQEFICFSLLQSPRCGSYSSLKTKRFGFCIRSKFSEKEAGKLDRGYVATVNSKEIKKVGKKEHHLWKKNDSAGSGQKALNLVRMLSGLPNEKEAVYGALNKWVAWEVEFPIIAAAKALQILRKRSQWHRVIQLAKWMLSKGQGATMGTYDILLLAFDMDERADEAESLWNMILHTHTRSIPRRLFARMIALYAHHDLHDKVIEVFADMEELKVSPDEDSARRVARAFRELNQEENRKLILRRYLSEYKYIYFNGERVRVKRYFSEDS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g18975, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS4_ALIB4
Sequence: MARYRGPVEKIERRLDADLGLKGERRLSGKSALEKRPFAPGQHGQRRAKISEYGLQLREKQKVKFMYGISEKQFRNYFKEAVRREGNTGAILISLIEQRLDNVVFRMGFATTRANARQFTTHGHVLVDGKKVDIPSYLVKPGQKIEIKEKSKSNPQVVRALELTNQTGMVDWVNVDKDKVFGIFTRIPAREEVVIPVEERLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CG22_YEAST
Sequence: MSNPIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSRIPQFTRESVSRSTAAQEEKRTLKENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKGVGSSTEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPISTIVEQELPKKFKVCDENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRNIHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGKGKWDGNLIHYSGGYTKEELAPVCHMIMDYLVSPIVHDEFHRKYQSRRFMKASIISVQWALKVRKNGYDIMTLHE
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: FLIT_SHIF8
Sequence: MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVAPSTTMQEQLRPMLHLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: JAG2_MOUSE
Sequence: MRARGWGRLPRRLLLLLVLCVQATRPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGPCSYGYGATPVLGGNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPDEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVPSGFECHCPSGWNGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCLPGWKGINCQININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYDKCASSPCRRGGICEDLVDGFRCHCPRGLSGLHCEVDMDLCEPSPCLNGARCYNLEGDYYCACPEDFGGKNCSVPRDTCPGGACRVIDGCGFEAGSRARGVAPSGICGPHGHCVSLPGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRCFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRGMSFPHGSSWMEDCNSCRCLDGHRDCSKVWCGWKPCLLSGQPSDPSAQCPPGQQCQEKAVGQCLQPPCENWGECTAEEPLPPSTPCQPRSSHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAAAHDRLLLLLCDRASSGASAVEVAVSFSPARDLPDSSLIQSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLACVVICVWWTRKRRKERERSRLPRDESANNQWAPLNPIRNPIERPGGSGLGTGGHKDILYQCKNFTPPPRRAGEALPGPAGHGAGGEDEEDEELSRGDGDSPEAEKFISHKFTKDPSCSLGRPARWAPGPKVDNRAVRSTKDVRRAGRE
What is the function of this protein?
Putative Notch ligand involved in the mediation of Notch signaling.  Plays an essential role during limb, craniofacial and thymic development.  May be involved in myogenesis and in the development of peripheral and central nervous systems.
What are the official names of this protein?
Protein jagged-2, Jagged2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SEPF_BACMK
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVPFAKVQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGISDHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEETNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: ATPL_STAA8
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGVGLVEALPIIGVVIAFMTFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BX3_LOXGA
Sequence: ADSRKPI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LgSicTox-beta-LOXN3, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLU_LACPL
Sequence: MEEINKTPKQIVAALDNYVIGQNQAKKAVAIALRNRYRRMELSAEMQEEITPKNMLMIGPTGVGKTEIARRLAKIVHAPFVKVEATKFTEVGYVGRDVESMVRDLVDVAIEMEKQQAYSGVRAQAVQAADKRLVKLLVPAQKKQAKNNGNEFQNMMNMFSQMQNGQTPNVDDSSNEEVTDEVRNQRLSVADQLKTGRLENSEVTIEMDDPQQAAAGNNNMLGQMGIDLGDSLGALMPKKRIQRTMPVSEAREILVREESEKLVNNADIYHDAIVRAENTGIIFIDEIDKITKGGQQGSGEVSREGVQRDILPIVEGSQISTKYGPINTDHILFIASGAFAESKPSDLIAELQGRFPIRVELDDLSKDDFVKILTEPKNALIKQYIALIGTDNIKVTFTIEAIEAIATIAYKVNHETQNIGARRLHTILEKLLEELLYEGPDMEMGEVTITESYVNERIGNIAQDKDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.