PharMolix/UniProtQA huggingface dataset:
Protein: CYOB_PSEAE
Sequence: MFGKLTLSAVPYHEPIVMVTLAVVALLGLGVVGAITYYRKWTYLWTEWLTSVDHKKIGVMYIVVALVMLVRGFADAIMMRGQLALAEGANHGYLPPEHYDQIFTAHGVIMIIFMAMPFMTGLMNLAVPLQIGARDVAFPFLNSLSFWLLVVSAMLVNVSLGLGEFARTGWVAYPPLSELAYSPGVGVDYYIWALQISGMGTLLTGINFLVTVFKMRTPGMKLMQMPIFTWTCTFANILIVASFPILTAALGLLSLDRYLDMHFFTNELGGNAMMYINLFWAWGHPEVYILILPAFGIFSEVTATFAGKRMFGYKSMVWASAAITFLGFTVWLHHFFTMGSGGDVNGFFGVATMLISIPTGVKLFNWLFTIYKGRLRFSTPILWTLGFMVTFTIGGMTGVLLAIPGADFLLHNSLFLIAHFHNTIIGGAVFGYLAGFAFWFPKAFGFTLDEKWGKRSFWCWLVGFYMAFMPLYILGFMGMTRRLNHYDNPLWKPYLVVAFFGAVLIFCGIACQLIQLFVSVRNRKQLADVNGDPWEGRTLEWATSSPPPFYNFAELPKVQDVDAFHDMKKAGTAYRKLPAYQPIHMPKNTAAGFSIAVFAFVFGFAAIWHIWWLMAVGFVGMIGSFIVRSYNQDVDYYVQPEEIEKIESARFQQLAKQV
What is the function of this protein?
Cytochrome bo(3) ubiquinol oxidase is the terminal enzyme in the aerobic respiratory chain.  Catalyzes the four-electron reduction of O2 to water, using a ubiquinol as a membrane soluble electron donor for molecular oxygen reduction.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron and generating a proton motive force.  All the redox centers of this enzyme complex are located within the largest subunit, subunit I.  Protons are probably pumped via D- and K- channels found in this subunit.
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 1, Cytochrome o ubiquinol oxidase subunit 1, Cytochrome o subunit 1, Oxidase bo(3) subunit 1, Ubiquinol oxidase polypeptide I, Ubiquinol oxidase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYRM4_TAEGU
Sequence: MAASSRAQVLRLYRALLRESQRFSSYNYRTYAIRRIRDAFRENKNIADSEKIEELLNKAKANLEVIQRQGTIDHMYATEKLIIERPGNT
What is the function of this protein?
Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.
What are the official names of this protein?
LYR motif-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: SUDX_DROME
Sequence: MADGNGLPAGAASGGMEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASLRNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKVLDHSSFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Down-regulates Notch/N signaling pathway, probably by promoting Notch ubiquitination, endocytosis and degradation.  Involved in wing growth and leg joint formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase Su(dx), HECT-type E3 ubiquitin transferase Su(dx), Protein suppressor of deltex.
Protein: THTR_MYCTU
Sequence: MARCDVLVSADWAESNLHAPKVVFVEVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCRIGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIELGS
What is the function of this protein?
May be a sulfotransferase involved in the formation of thiosulfate.
What are the official names of this protein?
Putative thiosulfate sulfurtransferase, Rhodanese-like protein.
Protein: MUTS_BACFN
Sequence: MNLKRRLSVSNDIELTPMMKQFLDLKAKHPDAVMLFRCGDFYETYSTDAIIAAEILGITLTKRANGKGKTVEMAGFPHHALDTYLPKLIRAGKRVAICDQLEDPKTTKKLVKRGITELVTPGVSINDNVLNYKENNFLAAVHFGKSACGIAFLDISTGEFLTAEGPFDYVDKLLNNFAPKEILFERGKRGMFEGNFGSKFFTFELDDWVFTESSSREKLLKHFETKNLKGFGVEHLKNGIIASGAILQYLDMTEHTQVGHITSLARIEEDKYVRLDKFTVRSLELIGSMNDGGSSLLHVIDKTISPMGARLLKRWMVFPLKDEKPINDRLNVVEYFFRKPDFRELIEDELHRIGDLERIISKVAVGRVSPREVVQLKVALQAIEPIKEACQQADNPSLNRIGEQLNLCISIRDRIEKEINNDPPLLINKGGVIKDGVDTELDELRQIAYSGKDYLLKIQQRESELTGIPSLKIAYNSVFGYYIEVRNVHKDKVPQEWIRKQTLVNAERYITQELKEYEEKILGAEDKILVLETRLYTELVQALSEFIPAIQINANQIARIDCLLSFANVAKENNYIRPVIEDNDVLDIRQGRHPVIEKQLPIGEKYIANDVLLDNATQQVIIITGPNMAGKSALLRQTALITLLAQIGSFVPAESAHIGLVDKIFTRVGASDNISVGESTFMVEMNEASDILNNISSRSLVLFDELGRGTSTYDGISIAWAIVEYIHEHPKAKARTLFATHYHELNEMEKSFKRIKNYNVSVKEVDNKVIFLRKLERGGSEHSFGIHVAKMAGMPKSIVKRANEILKQLESDNRQQGISGKPLAEVSENRGGMQLSFFQLDDPILCQIRDEILHLDVNNLTPIEALNKLNDIKKIVRGK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: LCFH_HAEIN
Sequence: MKIKNRVNMNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIDVQDKIAIFAHNMERWTIVDIATLQIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQTLEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGSNAQQDELTQRLNQKQLSDLFTIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYILHRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAISVGQKYFDLRANNKAIPFLLKKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLEPAIGLFFHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPKAEVKIGENNEILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKIGKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEHRINAVQKELAHFEQVKKFTLLSQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA
What are the official names of this protein?
Putative long-chain-fatty-acid--CoA ligase, Long-chain acyl-CoA synthetase, LACS.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: UFOG2_MANES
Sequence: FCTPMMDLADEFGIPSYIFFASGGGFLGFMLYVQKIHDEENFNPIEFKDSDTELIVPSLVNPFPTRILPSSILNKERFGQLLAIAKKFRQAKGIIVNTFLELESRAIESFKVPPLYHVGPILDVKSDGRNTHPEIMQWLDDQPEGSVVFLCFGSMGSFSEDQLKEIAYALENSGHRFLWSIRRPPPPDKIASPTDYEDPRDVLPEGFLERTVAVGKVIGWAPQVAVLAHPAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQFNAFEMVVELGLGVEIDMGYRKESGIIVNSDKIERAIRKLMENSDEKRKKVKEMREKSKMALIDGGSSFISLGDFIKDAMEG
What is the function of this protein?
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.
What are the official names of this protein?
Anthocyanidin 3-O-glucosyltransferase 2, Flavonol 3-O-glucosyltransferase 2, UDP-glucose flavonoid 3-O-glucosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: VTM2A_MOUSE
Sequence: MMGIFLASVGFMFFSVLYVQQGLSSQAKFTELPRNVTATEGQNVEMSCAFQSGSASVYLEIQWWFLRGPEDLEQGTEAAGSQVELLPDRDPDNDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTDANYGELQEHKAQAYLKVNANSHARRMQAFEASPMWLQDTKPRKNASSVVPSSVHNSANQRMHSTSSPQAVAKIPKQSPQSGARIATSHGLSVLLLVCGFVKGALL
What is the function of this protein?
Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation.  Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway.
What are the official names of this protein?
V-set and transmembrane domain-containing protein 2A.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by adipose precursor cells (PubMed:28052263). Not detected in the nucleus (By similarity).
Protein: DUT_RICM5
Sequence: MTITQVKIKKLENFSGSLPEYATEHSAGMDLIAANEQPITIKAGAIQLIPTGIAIALPDSFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVILINLGKEDFIIEKGMRIAQMIIAKYERILWEESSSLMETMRGSGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: AROD_STRGC
Sequence: MKLVVSVTPRNLEEAQQIDAQRFVDADLIEWRADFLEKEEILKVAPAIFEKFAGRELIFTLRTKDEGGHIQLSDDEYVEMIKKVAQLYQPDYVDFEYFSHKDKIDEMLEFPNLVLSYHNFEETPENMMEILSELTSLTPKAVKVSVMANSGQDVLDLMNYTRGFKTLNPEQEYVTISMGRVGRISRIASDLTGSSWSFASLDEATAPGQISLSSMKKIRDILNEN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: Y502_TREPA
Sequence: MKVVLFYDQGRAHSVAAICEVLCAQGCAVTPHAIEQVWNDTSPCSTPLALVQDATHVFFLYAHEPMRDPAFIFFSGVACGRGMHVLLLATTTEVRDIHVFRDLVFLLEEETFEDFFRVEHERFVRQKKKRVARTALLERGYPCFEENFIATVMDGNIDIVNLFLDAGFSAALKDARGTPVLSLAVREGQDEMAAQLIARGAPVDQLSDDRAYSALMEAAQIGNRTVARLLLHAGADPNVRGSNGQTALVLAVGRKDHVLIRLLMDHGANPYLEDKLGLSAQGYAKLFNDPTLCTLVGV
What are the official names of this protein?
Putative ankyrin repeat-containing protein TP_0502.
Protein: CP8B1_PIG
Sequence: MVLWGPVLGVLLVAIVGYLCLQGLLRQRRPEEPPLDKGSVPWLGHAMTFRKNMLEFLKHMWARHGDIFTVQLGGQYFTFVMDPLSFGPILKDAKRKLDFVEYAEKLVLKVFGYRSMQGDHRMIHSASTKHLMGDGLEELNKAMLDNLSLVMLGPKGPSPDASCWREDGLFHFCYDILFKAGYLSLFGRTEDKEQDLLQAEELFMQFRKFDRMFPRFVYSLLGPREWLEVGRLQCLFHKMLSVEHSLERHGISSWITDMLQVLREQGVAPAMQDKFNFMMLWASQGNTGPTTFWALLFLLKHPEAMRAVREEATRVLGEARLEDKQSFDVEVSALNHMPVLDSVMEETLRLGAAPTLLRVVNSDQILKMASGQEYRLRHGDILALFPYLSVHMDPDIHPEPTTFKYDRFLTPSGSRKVNFYKAGKKIHHYTMPWGSGISICPGRFFALTEMKLFVLLMVTHFDLELVDPDTPVPPVDPQRWGFGTMQPSYEVRFRYRLRPTE
What is the function of this protein?
A cytochrome P450 monooxygenase involved in primary bile acid biosynthesis.  Catalyzes the 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one, an intermediate metabolite in cholic acid biosynthesis (PubMed:14643796).  Controls biliary balance of cholic acid and chenodeoxycholic acid, ultimately regulating the intestinal absorption of dietary lipids (By similarity).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase) (By similarity).
What are the official names of this protein?
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase, CYPVIIIB1, Cytochrome P450 8B1, Sterol 12-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: CBPM_ECOHS
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: NAL10_MOUSE
Sequence: MALARANSPQEALLWALNDLEENSFKTLKFHLRDVTQFHLARGELESLSQVDLASKLISMYGAQEAVRVVSRSLLAMNLMELVDYLNQVCLNDYREIYREHVRCLEERQDWGVNSSHNKLLLMATSSSGGRRSPSCSDLEQELDPVDVETLFAPEAESYSTPPIVVMQGSAGTGKTTLVKKLVQDWSKGKLYPGQFDYVFYVSCREVVLLPKCDLPNLICWCCGDDQAPVTEILRQPGRLLFILDGYDELQKSSRAECVLHILMRRREVPCSLLITTRPPALQSLEPMLGERRHVLVLGFSEEERETYFSSCFTDKEQLKNALEFVQNNAVLYKACQVPGICWVVCSWLKKKMARGQEVSETPSNSTDIFTAYVSTFLPTDGNGDSSELTRHKVLKSLCSLAAEGMRHQRLLFEEEVLRKHGLDGPSLTAFLNCIDYRAGLGIKKFYSFRHISFQEFFYAMSFLVKEDQSQQGEATHKEVAKLVDPENHEEVTLSLQFLFDMLKTEGTLSLGLKFCFRIAPSVRQDLKHFKEQIEAIKYKRSWDLEFSLYDSKIKKLTQGIQMKDVILNVQHLDEKKSDKKKSVSVTSSFSSGKVQSPFLGNDKSTRKQKKASNGKSRGAEEPAPGVRNRRLASREKGHMEMNDKEDGGVEEQEDEEGQTLKKDGEMIDKMNG
What is the function of this protein?
Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID (By similarity).  Displays anti-inflammatory activity (By similarity).  Required for immunity against C. albicans infection (PubMed:23071280).  Involved in the innate immune response by contributing to pro-inflammatory cytokine release in response to invasive bacterial infection (By similarity).  Contributes to T-cell-mediated inflammatory responses in the skin (PubMed:27221772).  Plays a role in protection against periodontitis through its involvement in induction of IL1A via ERK activation in oral epithelial cells infected with periodontal pathogens (By similarity).  Exhibits both ATPase and GTPase activities (By similarity).
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 10.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Cytoplasmic protein which is recruited to the cell membrane by NOD1 following invasive bacterial infection.
Protein: DPS_BREBE
Sequence: MKTSIQQLVAVLLNRQVANWVVLYVKLHNFHWNVNGPNFFTLHEKFEELYTEASGHIDTLAERVLSIGGSPIATLAASLEEASIKEATGGESAAEMVSSVVNDFVDLVGELKVARDVADEADDEATADMLDAIEAGLEKHVWMLEAFLE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity).
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YFN1_SCHPO
Sequence: MMQQRSGSLSLLSNAVQAGQSSDPMQDDPAKTEPGTPKGYDGSKNSSPASVPSWIHEKTKAGKDRKRLPLACQSCRKKKVKCSGERPSCDQCLKHNIPCIYKSNSTKRSHSRHEEIHHQQQLHLNHQYQHQHKNVAANSIDNLSRQYSQPNHINTHDSVNSPPSYGIMASATNQPLSHPTIVPSSNSSSLLNSTNNISHNPQVSLMSASLSKNLVLDPASPKSVSPDLVYVSSDNPPVSTAASAYSSSLPISDVTRALPLAPASNSQHPSLSSQPVSVPSNTINIPTDSLSIVSNPSQTPAKFDSNRISQVPNSDYSIYSNFNNFPIANHAPSFPQSSVKKLDSSFSPTSLPTFTTNSASSGLSTSYTNNNDTTSDNNSLQAVPRLDPVPSLTLSSTPVAELPPLELRIHLAEVFFHCCHGQSYNLFHRPTFFESLNNNTVPLVVVYAVCAVSARFSSRMHDRFSPPYMAGEQYAREARRLALDNFDRPDLSLVAALLLLSLHDSGTCETGKSWMYGGMALRMAAALQLNCEQGSNPLDLDNIDSGPRISFLERELRRRTFWSCFLMDRYASSHEHLQFLDENDIGIQLPVHELLFTKQIAGVTQTLDGRILEGVPSIVIPADTTENMGVAAYTVKIIALWGRAVKYLKQDGKRRDPYPYWHRNSDFSHISEALYAWADGLPQRLKYSAVGLENHLSIQQGAQYAFLHLAYHHTLMWLFRSIGETENNQLSKISSSVSLAGNTVSFSPVSHTPINVTNGESQNNSNNDPSANGAARRLHKAAREICLRCANAISMIVDDCRKHNVILTSPFIASGVYTAFCVQAEAAFGSNVLAASTARHNLEIDLRLMLEMKNYWGSISALCDKMSEIWADWVQRTSSGIQEEDTIPNEMIDEERMLDLEKHFMYITESPIVPNQAAQKSYSPDLMSYFGFAKNSDLQQWNGLWPSDDLRNYQESTIDSLVAYATGNPGWNISFAG
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C1327.01c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR7_NASOF
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAB_HELAH
Sequence: MLKVYIETMGCAMNSRDSEHLLSELSKLDYKETNDPKIADLILINTCSVREKPERKLFSEIGQFAKIKKPNAKIGVCGCTASHMGADILKKSPSVSFVLGARNVSKISQVIHKEKAVEVAIDYDESSYAFEFFEKKAEVRSLLNISIGCDKKCTYCIVPHTRGKEISIPMDLILKEAEKLANNGTKELMLLGQNVNNYGVRFSSEHAKVNFSDLLDKLSEIPGIERIRFTSPHPLHMNDEFLERFAKNPKVCKSIHMPLQSGSSAVLKMMRRGYNKEWFLNRVEKLKALVPEVGISTDIIVGFPNESDKDFEDTMEVLEKVCFDTLYSFIYSPRPFTEAGAWKERVPLEVSSLRLERLQNRHKEILEEKARLEVGKTHVVLVENRHEVDGQIVGFEGRSDTGKFIEVTCKEKRNPGELVEVEIISHVKGRLMATTKNNQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3318_BRUA2
Sequence: MTETPLLSVRGLAKHYQTRSATLKILDNVSFDIARGEVVGLVGESGSGKTTIGRSVLRLIEPTAGQIMFDGADVATLSAREMRRQRRRMQYIFQDPFASLSPRMTIGEILMEGLNIQGIGTKAERLERARKALEQVELPPDTINRYAHEFSGGQRQRIGIARALTLEPDFIVADEPVSALDVSIQAQVVNLLRDLQQRLGLTMLFISHDLAVVEYICDRVIVLYLGRIMEIASSEDLYARPQHPYTRALLSAIPSPDPDARTERQILRGDIPSPANPPSGCVFRTRCPMAIDACATTVPQLREVRPGHFKACIRDNI
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative peptide import ATP-binding protein BAB2_0818.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNZ_CLOBA
Sequence: MIDLCILGTTGGMPMVNKYLSATLININGRKILIDCGEGTQVAMREIGWGFKSIDLICITHSHGDHTIGLPGLLSTMGNSGRTEKVIIVGPKGIKEIVNGLNIINPYLPYELEVVELENNDLKFIIDKNNMFLCEDNDKCNLILSSLEVEHSAKCLSYSFYIKRRPRFSVEKASKNNVPKLLWSKLQNQEIVNYDNKIYTPDLVLDNARKGIKISYVTDTRPISTLPQFIKYSDLFICEGTYGSDEDIDKAIKNKHMTFRESATLAKKGECNELILTHFSAALSAPENFLNNAKEIFHNSIVAHDGLIKTLKFID
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RS2_AZOPC
Sequence: MLRVSFEQLLEAGVHFGHLKRKWNPAMAPYIFMERKGIHIIDLHKTILKIDEASSAIKQIIRSGRKILFVATKKQAKQVVADKVSFVGMPYVTEHWAGGMLTNFPTIRKAIQKMTVIDRMAHDGTFDLLSKRERLQITRQRAKLEKNLGSIADLKRLPSALFVVDVMKERIAVSEAKRLDIPVFAIVDTNSNPNGIDFIIPANDDATSSIEVILNAICDAIIEGKEERMMDTSINNENKEKTVSVFRKRTKIEGRSKKDSLS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: EFNB3_MOUSE
Sequence: MGAPHFGPGGVQVGALLLLGFAGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPSYEFYKLYLVEGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSAEPGRDTIPGDPSSNATSRGAEGPLPPPSMPAVAGAAGGMALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGTADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV
What is the function of this protein?
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  May play a pivotal role in forebrain function.  Binds to, and induce the collapse of, commissural axons/growth cones in vitro.  May play a role in constraining the orientation of longitudinally projecting axons.
What are the official names of this protein?
Ephrin-B3.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PGTA_RAT
Sequence: MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVWLCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSVSSILT
What is the function of this protein?
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
What are the official names of this protein?
Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type II subunit alpha, Rab geranyl-geranyltransferase subunit alpha, Rab GG transferase alpha, Rab GGTase alpha, Rab geranylgeranyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: RL32_MANSM
Sequence: MAVQQNKKSRSRRDMRRSHDALTTAAVSVDKASGETHLRHHVTADGYYRGRKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: YAJC_THEMA
Sequence: MPEIIYAAAPGASNGTTTTATGGGWGSLLFMLIFFIAIFYFMIILPQRRREKQFQQMISQMKRGDTVVTIGGIVGKVIDIKKDTVKIKTANSTELEITKRAISTVIKERSQENQEG
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.