Protein: FSDS_FUSHE
Sequence: MSAPPTKQTEPIAVVGSAGRFPGGCNTPSKLWDLLRSPRDLLREIPKERFNIDAFYHPDPLHHGTTNTRYSYFLDEDPAQFDAQFFSITPAEAEAIDPQQRLLLETVYESLCAAGLPIERLRGSDTGVYIGLMCDDWSSMIQKDIDALPTYTGTGTARSILSNRVSYFFDWQGPSMTIDTACSSSLVAVHEAVRLLRSGDSTVAIAAGANLILNPTQYVAESNLRMLSPTGRSRMWDASADGYARGEGIASVVLKTLSQAIADGDSIECIIRETGVNQDGRTSGLTVPSNIAQTKLIRETYARAGLDLSKPSDRPQLFHAHGTGTKAGDPQEAQAIHNAFFSGSQSQDAVEDADELFVHSIKTIIGHTEGTAGLASLIGTSLAIQNSTIPPNMHFKMLNPDIAPYYKHLKVPTSARPWPTLLDGGVKRASINSFGFGGTNAHAIIEEYVPQVNAVPILSTPASAHFTPLVFSASSSASLKTVLADQLKYLMSNPQVSLRELSWTLAHRRSTLSYRKYISGRSYDDLCINLGEALNSEDSNLDARSANVEEPKILGVFTGQGAQWARMGAELLEASPFVEKRIAELDESLASLPESDRPEWTIREELLADDLASRLSEAALSQPLCTALQMILVDLIESAGIKFAAVVGHSSGEIGAAYAAGFISAHDAIRIAYYRGVHTKLASSPNKDVKGAMAAVGMTVEEAAGLLEEHSLSGRISIAAFNSSSSLTLSGDEDAIDETVEILKGQSKFARRLKVDKAYHSAHMQSCAESYLQSLQNCNMKPLEPTGHRPQWFSSVSEDVTMTSTLCGSEYWVRNMTQPVLFSDAITSAVDNIGSFNLAIEVGPHPALKGPAVDNLTENGVVLPYTGLLARGKDDIEQFSSALGFVWTNLSAGSVDFGTFDKTINGDDATMTVMKNLPSYPFNHQYSYWAEPRSSRTYKQLKTRPNPVLGMPNVTTTTSSEAQWRNMLSPKEVPWMQGHKLQGQIIFPATGYIAMAIEAVKALAGGKCLSQIRVEDLLLERAIAFNDDSATTETLFSVNIDDSDHDSISATFACYSCPDGDHSMIRNAVGRIYVKLGPSEASSLPFTSAEAGFNMVDVGIDRFYKELSRIGYNYAEPFKGMTSIRRRLGIARGVLADQSGSAWEDELVIHPGMLDTALQTLFAAFSYPGDESLRSLHVPVSIDSIIINPYFSPVNDMKQLHVPWETVVRDDDKSHIKADVQLFSEDSQHTFVQIEGVSLKPFTVARPEDDVTLFSHFEYLRDSPDGESAAIGDRLGPDELRSARDMERIAFFYLRQVSEMSVDDRAQALKHHQHLMAWADYTVEKCRKGDHPSVAPECLNDTQADILALTDKYRHHVDALLIESTGQNLPATIRAKDSILQHMTKDNLLGRFYEEGIGLSTANWWLAHMVKQISHRYPAMKILEIGAGTGGTTQATLPSLGTSFSSYTYTDVSSGFFEAAEDKFKTYADRMVFKVFDMVKSPAEQGFTEGSYDMILASNVLHVAEDLDVMMGNVRKLLKPGGFLVNLETVTNDMLRNGIIMGGLPGWWIGAESGRPHGPMLDLASWNSLLKRCGFGGIETSTPVYDSIHAVAVWAAQATDDRVALLKDPLAAQPSTKADAHLVIVGGSSLSTFALLESVKSHLQDRFSSFEHLRSVESLDKTTLPPGSTVLSLADLDEPVMKSVTQAKMDGLKTLWTQARNILWVTKGVRYENPFSYMMFGIGRVVRFENPNINLQLLDVDSISDEVGSYISEALLRHQFLDNWKKERDVVDMLWSSEPEVFLSQGTTLMPRLYQNKAQNDRINSIRRKIVQDIDPKTTSLRLVEEGGAVDLEQVSPLELMASIPDHANRREIAFKQTLLQAIQVGDLGKLTLFIGADPESPKSAVLGLTETLTSPALVDASCTVEIPDSAEFGRMALVTTAAHLVADNLVHNIPKGANLMIHEADKLLRTAVSFKAKASGITTLFTTSRSDRRSSDCTFVHTALPTRLLKKLVKDNTCAFVDLSPPGSLSSDVGRAISKELPSCCSYRASRDLLGSIPRLRPGSSLSDARERLSKAWSDATKATVPIDEVGSISLNDISNHHPADEPLTVVDWTASTVRVRIRPIDRNDIFRPDRTYLLIGLSGEVGQSICQWMVSHGARHVVLTSRKPGVDPAFIHHLESLGADVRSMSLDITSRDSLMRCLDTIKRTMPPIAGVSNGALIVADSPFTEMTLDGMNKVLKPKVDGSMLLDEVFYDEPLDFFIMFSSLTACLGNSGQSNYAAANMFMTTLAFQRRARGVPGSVIDLSSLMGIGHVGRSDVFNADYFRSLGATSVSEVDLHQMFAEAIHVGRPDSKESAEIVTGMSPMLRSELEDMKVQYRMDLKFGHFCLEQSCNKGETSASSKVPVRVQLKTVKTRGEAMRVLLDSLVARVKKVLQIPADEVVHETEPLIERGVDSLVALDIRSWFMKELDVDMPVLKVLGGNSILDLIKDSLERLPSSVLDTSTLTEDLDIPARRQPATKPLPEAPSAEDLYIHADNLLPAPSTAPSLNGTSTPTSTTSNDGTGSSYPASNAENDIKAPTVRDSIINSSTEVTELMSFGQTRFWFLHHALQDSTTFNVAVSVRLEGMMELERFERALEAVAEKHEAMRTRYFWGGEEGDIPMQGILSKPLVRLNHKRISDRAEAGKALEEMRDVKWDLNDWESMKFVLLSLSDNTHWLIFGCHHITIDGVSIQLIFADLEMAYQGQILTLLPDKSQYRTYSTLQRKQFELGSFQKDIDFYRNIIPSDVQPIPLLSFSKLTARQPQTSYKTFRADIRLDASSTAQIKQIARHNQATNFHLYLSVLQALLFRLLPNTNEIFIGIADANRNDEQFLQTLGFFLNLLPIRFERPSHKTKFGGSIKNARNKVYAALEHSALPFDLLLSELGVSRSANSPPVFQVFVDYRQGTQERAKFASFDAAGEEWYHPRTGYDISLDLLENSEGDTLVTLQLQQSLYTQEQTELFARAYVNLLKGLTKTPGGDIPIMAPSVWADEDITKALQVGKGPETPLSWPETVSHRIDEVVKDFGSKPALKVGTNTALTYEDMGRRVDAIAQYMVSKGVANGDVVGIFQAPGTDWICSMLAILRIGATYLPLDLRNSIHRLQDSVRIAKPDMLLVDPSTLETLKSITTGNAEVMDISAIPHNTSVAHQVSAARGQDTAVILFTSGSTGEPKGIRIKHSNLVAQNEGFSKQCNISPGEAFNVLQQSAFSFDFSLEQIFVALCNGGCLHIVPSEIRGDPFEVTRMILEENINYTSGTPTEYEMWLRNAPEHLTQCHQWNFAFFGGEAFSDEFVSDFRKLGLSDLKVFNNYGPSETTIACTHQGRIDYRNSDLECPLPAGFAAPNYAIYTVDENLNLLPINVPGEVLIGGAGVTGGYVDLDSLTQERFLPNKFIQPGSHLANNGWNTLYRTGDRGLLREDGGLVIRGRIDGDTQVKIRGFRVELAEIETIILESSKGSLKHAVVTLRESEGAGFLAAHVVFSRHHPEAGRAEYLAGLQAKLQVPDYMRPAIIVALDQLPVTAHSKFDRAAVKALPLDAPLSTERDLADGREMTPVEAKLEELWRSVLPFTPTTAITPESNFFHVGGSSLLLVKLHRMVKQRFSAAPKLVELMNAGKLSDMTAIIEATLSTKIDWAAETAVPDTWSEDFPMPLVKTSPQVQGRGLNVLLTGATGYLGRHLVPALVQSAQIEKVFCLVRHESDVDALRKASEKIIIYTGDLGEVDLGLSKDEFSQLSRDSDIILHSGANRSFWDDYEVLRPANTNSIKELARLALPRRIPFHFISSGSVRIYGDEEGPKIYNIDQSLPISPTPPSDGSDGYVASKWAAEKFLRTVASQLQLPVTIHKPMPVPGYGPDDSHAEPESDHMVNELVDITKRLQVRPTMEGLQGWADILDTQSVVNDILDSILSEQGVELQEVLHTAVRRINWQRFIAELHSNPELSCLPSKDTLLWIGQAKRSGYSYLMPAHRLVVVNDDDDEMVSRR
What is the function of this protein?
Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of fusaridione A, a bright yellow trans-fused decalin-containing tetramic acid with antimicrobial activity (PubMed:23614392).  The PKS module of fsdS catalyzes the formation of the polyketide unit which is then conjugated to L-tyrosine by the condensation domain of the fsdS NRPS module.  Activity of the Dieckmann cyclase domain (RED) results in release of the intermediate fusaridione A (PubMed:23614392).  The unstable pyrrolidinedione ring of fusaridione A is opened through a reverse-Dieckmann reaction to afford its ring-opened form (PubMed:23614392).
What are the official names of this protein?
Fusaridione A synthetase fsdS, Fusaridione A biosynthesis protein S, Hybrid PKS-NRPS synthetase fsdS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NRP synthetase family.