PharMolix/UniProtQA huggingface dataset:
Protein: SCN4A_HORSE
Sequence: MASSSLPNLVPLGPESLRPFTRASLAAIERRALEEEARLQRNKQMEIQETERNARSDLEAGKNLPLIYGDPPPEVIGIPLEDLDPYYSNKKTFIVLNKGKAIFRFSATPALYMLSPFSIIRRSAIKVLIHSLFSMFIMITILPNCVVMTMSDPPPWPIHVENTFTGINTFESLIKMLARGFCIDDFTFLRDPWNWLDFSVIMMAYLTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPQPFNDTNTTWYGNDTWYSNDTWNSNDTWSSNDMWNSHESMASNYTFDWDAYINDEGNFYFLEGAKDALLCGNSSDAGHCPEGYKCIKTGRNPNYGYTSHDTFSWAFLALFRLMIQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVTMAYAEQNEATLAEDQEKEEEFQQMMEKFQKQQEELEKAKADQALEGGEAGGDPAHSKDCNGSLDTSPGEKGPPRQSCSADSGVSDAMEELEEAHQKCPPWWYKCAHKVLIWNCCTPWVKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDKVLTVGNLVFTGIFTAEMVLKLIALDPYEYFQQGWNVFDSIIVTLSWVELGLVNVKGLSVLRSFRLVRSLKLAKSWPTLNMFIRIIGNSGGGLGNLTLVLAIIVVNFSVVGMQLFGKNYKECVCKNASDCALPRWKMCDFFHSFLIVLRILCGEWIEPMWGFMEVAGQAMFLTVLLMVMVNGNLVDLDLFLALLLNPLNSDNLSASDEDGEMNNLQISSWPIKLGICFANAFLLGLLHGKILSPKDIMLSLGDPGEAGEAGEAEESAPEDEKKEPPPEDDDKDLKKDNHILNHMGLVDGTPTSIELDHLNFINNPYLTIHVPIASEESDLEMPTEEETDTFSEPEDGKKPLQPLDGNSSVCSTADYKPPEEDPEEQAEENPEGEQPEECFTEACVQRFPCLSVDISQGRGKMWWTLRRACFKIVEHHWFKTFNSSLILLNSGTLAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWVIFSIMGVNLFAAKIYYFINTTTSERFDISGVNNKSECESLIHTGQVRWLNVKVNYDNVGLGYLSLLQVATFKGWMDIMYSAVDSREQEEQPQYEVNIYMYLYFVIFIIFGSFFTINSLIRLIIVNFNQQKKKLGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDFVTKQVFDITIMILICLNMVTMMVETDDQSQLKVDILYNINMVFIIVFTGECVLKMFALRQNYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLILVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPTLENPGTSVRGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSDPLGEDDFEIFFEKWEKFGPDATQFIDYSRLSDFVDTLQEPLRIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKETMEEKFMAANPSKVSYEPITTTLKRKQEEVCAIKIQRAYRRHLLQRSVKQASYMYRHSQDGSGDGAPEKEGLIANTMSKMYGRENGNSGVQNKGEERGSTGDAGPTMGLTPINPSDSALPPSPPPGLPLHPGVKESLV
What is the function of this protein?
Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient.  Alternates between resting, activated and inactivated states (By similarity).  Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K(+) levels (PubMed:1338908).
What are the official names of this protein?
Sodium channel protein type 4 subunit alpha, Sodium channel protein skeletal muscle subunit alpha, Sodium channel protein type IV subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GDT11_ORYSJ
Sequence: MASVASSTVFASSLPHHRATTRAPPTPPRIPRRARLPGRSVVSCLPKRGSEKLVVTRASDEEGPPEPAGQGRGGGRAWPSLDASSCGLALAAAAGVLMLQGSQQALAGTEFMGMQDVVGDLGDISTGFASAFLLIFFSELGDRTFFIAALLAARNSGAIIFLGTFGALAVMTIISVVLGRAFHYVDGIIPFSFGGTDFPVDDFLAACLLVYYGITTLLDAASGDEEKMNEEQEEAELAVSKFLGNGAGIISAASTIASTFVLVFIAEWGDKSFFSTIALAAASSPLGVIAGSLAGHAVATLIAVLGGSLLGTFLSEKIVAYIGGSLFLAFAAVTLVEIVNS
What are the official names of this protein?
GDT1-like protein 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: SCC4_DROGR
Sequence: MSVANTTAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFQPPSKVEARTHLQMGQVLMAYTCNIDLARRHLEQAWSISEPLMNFDDVKFDTASLLAQLHLKTEQSPHAKAMLRRAVELSQNNVYWHCKLLLQLSQIHANDREYSLASDLLAVGAESAEEAGATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDESIFGGNQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKLQEDKSILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCLAVPHRSLLKRHSAQLHCLIGLYSMSTSFFEHAERQFLVCVNETGERDLKLFANLNLAIIYLRTKRDADLKQILDAVSTENTHTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDVQHEKEAYANHVKYSENLIADQRKCVQSAHHELVNWFQGDPPLTSGASLTHLPVAAAAPEASTSSLQASTAQFGQFY
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: TOP1_STAA8
Sequence: MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: BACC_BACSU
Sequence: MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADGGYTAQ
What is the function of this protein?
Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase.  Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S-tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala).  It is not able to oxidize the 4R-H4Tyr diastereomer and the dihydrobacilysin dipeptide (L-Ala-4S-H4Tyr dipeptide).
What are the official names of this protein?
Dihydroanticapsin 7-dehydrogenase, Bacilysin biosynthesis oxidoreductase BacC.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS3_ECO24
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: KIF7_MOUSE
Sequence: MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHGHQSCLRVEPERGRITLGRDRHFGFHVVLGEDTGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLELYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHFNRLSSRSHTVFTVTLEQRGRTPSRLPRPAAGHLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSTLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWHPEAERVPEEQAAGARGPPRHRSETRIIHRGRRVPCPAVGSAAVAAGLGAECARCRARTSAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSTLSSASGPDSGIESAPAEDQAAQGTSGRKGDEGTQQLLTLQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMVELRLRLELAQPGWGAPGLLQGLPPGSFVPRPHTAPLGGAHTHMLGMMPSTCLPGEEVSSEQQVVSGKEVKAEVLAQADKLRSASSTTSEEEGEEEEEEEEEEEEPPRRTLYLRRNGISNWSQRAGLSPGSPPDRKGPEVCPEEPAAAIPAPQAVGSGKVPVQTRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAERVRAELCEGQRQLRELEGREPQDASERSRLQEFRKRVAAAQSQVQVLKEKKQATERLVSLSAQSETRLQELERNVQLMRRQQGQLQRRLREETEQKRRLETEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELRKREVILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQNQQQIRGEIDTLRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNVQLLLQQGRDHLGEGLADSKRQYEARIHALEKELGRHMWINQELKQKLSAGSTAGQSQGCERRSLCLENRQCLGNEDGLHPAAPEPLWQSSLLEGVSRVWDESRDLVHAPLPLTWKRSSLCSEQGSSEESRVRETTEPPVGRVLPMGEVGLSWNFGPLPKPRWEPRRTSPGMIDVRKNPL
What is the function of this protein?
Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms.  Involved in the regulation of microtubular dynamics.  Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes.  Required for localization of GLI3 to cilia in response to Shh.  Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand.  Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form.  In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation.  Involved in the regulation of epidermal differentiation and chondrocyte development.
What are the official names of this protein?
Kinesin-like protein KIF7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to the cilium tip.
Protein: HPCAS_SULTO
Sequence: MTEKLSEQLQQLGEQNLEEKADYNMRYYKYLYKKSIEEPDKFWGELAEELITWYEPWKQAFVQEEGLLTKWFVGGKLNASYNAVDRHLNSHRKYKAAIFWESEKGEKKVVTYQDLFYEVNKWANALRELGVKKGDRVTIYMPLTPEGVIAKLAVARLGAIHSVVFAGFGAQALADRIADAGAKVVITADAYYRRGKLVELKKTVDEALNILGDKSPVQKVLVYKRTGTEIPFKEGRDVYFDEVGKYKYIEPVPVEATEPLFILYTSGTTGKPKGIVHSTGGYLVGTAVMLLWSYGLSQENDVLFNTSDIGWIVGHSYITYSPLVMGRSIVIYESAPDYPYPDKWAEMIEKYRATTFGTSATAIRTLMKYGEDYVKQHDLSSLRIIVTNGEPLNYAPWKWGLEVVGGGKVFMSHQWWQTETGGPNIGYIPGVVYLPMKSGPAVGFALPGNKVTVVNEEGKETKPRERGYLVMLPPFPPMMMIGMWNDPDNERLKKTYFSKFPGIYYPGDYAMIDEDGYIWVMGRADETIKVAAHRIGAGEVESIVTSHPAVAEAAAVGIPDPVKGEAVHLFVVLKVGYKPSPQLAREIQEHVRKYMGAIVTPEVHFVDKLPKTRSGKIMRRVIKAVMMGQSAGDITTLEDEASMDEIKKAVEEFKKSLSQ
What is the function of this protein?
Plays a role in the autotrophic CO(2) fixation pathway.  Activates 3-hydroxypropionate to its CoA ester.  Can also activate propionate, and to a lesser extent acrylate, acetate and butyrate.
What are the official names of this protein?
3-hydroxypropionyl-coenzyme A synthetase, 3-hydroxypropionyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TUSA_ECO8A
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUC_ECOLI
Sequence: MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEGVVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV
What is the function of this protein?
Part of a binding-protein-dependent transport system for aliphatic sulfonates.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Putative aliphatic sulfonates transport permease protein SsuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAGB_LISMF
Sequence: MQLITTENKLAGSKKALEIIEKGITSGEVNTLGLATGSTPETLYAELVKSDVDTKNVTTTNLDEYVGLAANDPNSYHYYMNELLFSKKAFKESFLPNGEATDAEAECARYEEILSEHPIDIQVLGIGTNGHIGFNEPGTPFDSLTHKVVLTDSTREANKRFFEREEDVPTHAYSMGIKSIMNAKKIILLAFGENKAQAIKETIKGPVDVNCPASVLQNHPDVTVILDNEAASLL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: TAT_HV1VI
Sequence: MEPVDPSLDPWNHPGSQPTTPCTKCYCKRCCFHCQWCFTTKGLGISYGRKKRRQRHRTPQSSQVHQNSLPKQPLSQARGDPTGPKESKKEVESKAKTDPCA
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: URK_PECCP
Sequence: MTDQSHQCVIIGISGASASGKSLISSTLYRELRDQVGDQHIGVISEDSYYKDQSHLTMEERVKTNYDHPSSMDHSLLLKHLQMLKAGQAIEVPQYSYVEHTRKQETVHIELKKVIILEGILLLTDARLRDEMNFSIFVDTPLDICLLRRMRRDVNERGRSMDSVMEQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_METMP
Sequence: MDKYDKIIDLTKRRGFLWNSFEIYGGIAGFFDYGPLGAILKNNVINTWRKHYIVNEGFYEIDSPTVTPYEVLKASGHVENFTDPLVECKDCLESFRADHIIEENVDVDTEGKTLQELQEMIEKNNIRCPKCGGEFKEVSTFNLMFATSIGPGGKRAAFMRPETAQGIFIQFKRISQFFRNKLPFGAVQIGKAYRNEISPRQGVIRLREFTQAEGEFFIDSRKKENFEKFESVKDMVLPLLSGKNQEDESLSSEEKVVKMSLSDAVKNGIIAHEAIAYYIAVTKKFLMEIGIDETKLRFRQHLPNEMAHYAADCWDAELYTDRYGWIECVGVADRTNYDLLAHMKNSGDDLSVFVELDEEHEIEAYEIELNYKLVGRTFKGDAKVLEESLKELDDKKMEELVEALETEGKYVLKTCKRDFEILKEYLTAKKVKKIVKGEKIIPHVIEPSYGIDRITYCVMEHAFKEDEDRTVMGFSNAVSPIKVGVFPLVNKEGMPEIAMDLKNKLRENGLIAEYDDSGAIGRRYMRMDEVGTPFCITIDGETLKDRSVTIRERDSREQFRIPINEVVPYIKDKL
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_YOMV
Sequence: MVYNITSSNQYQYFAAMWAEPTAMLNQCVSALSQSYQTQAARDTVRQQFSNLLSAIVTPNQRFPEAGYRVYINSAVLKPLYESLMKSFDTRNRIIETEEESRPSASEVANATQRVDDATVAIRSQIQLLLNELSNGHGLMNRAEFEVLLPWATAPAT
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: VPS18_DANRE
Sequence: MASILDQYEDSQNIRQHSRMSTANIGITHSGFVNVRLEEEKPIFTKQRIDFSPPEKINQFSVCNNQLCMSLGKDTLLRIDLGKPDQPNQIELGRKDDSKVHRLFLDPTGSHLVICLTTNECVYLNRNTQKVRGLSRWRGHLIESIGWNKLIGSETNTGPILVGTSQGIIFEAEISASEGSLFNTNPDQYFRQVHYLEEDGKPAPVCCLEVERGLETKYFIIATTRKRLFQFVGKLAEGSEQQGFSSIFAQNQDLLPSFQEFPVNMGYSEITFYTSKLRSRPKTFAWMMGNGVLYGQLDYVRPDSLLSDVQVWEYTQDIDLNFVKPISIVLTQFHFLLLLPDRVRGICTLNGQVVHEDVFPEKFGTLQKMIKDPITGLVWIYTEKAVFRYHIQKEARDVWQMYMNMNKFDLAKEYCKDRPECLDMVLAKEAEHCFQNKRYLESAKCYALTQNYFEEIALKFIEAKQEEALKEFLIKKLVNLKPSEKTQITLLVTWLTELYLNRLGQLEADEGKQHLFLETREEFRTFLKSPKHKDCFYNNRSTIYDLLASHGDVDNMVYFSVIMQDYERVISHYCQHDDYSAALDVLSKHCDDKLFYKFSPVLMQHIPKKVVDAWIQMGNRLDPKNLIPALVNYSQMGSMQQINETIRYMEFCVYELDVKEEAIHNYLLSLYAKHKPDALLWYLEQAGTHVSDIHYDLKYALRLCSEHGYLQACVLVYKIMELYEEAVDLALKVDVDLAKSCADLPEDDEELRKKLWLKIARHVVQEEKDVKKAMNCLSSCNLLKIEDILPFFPDFVTIDHFKEAICSSLEEYNKHIEELKQEMEEATESAKRIREDIQEMRNKYGVVESQEKCATCDFPLLNRPFYLFLCGHMFHYDCLLQEVIPHLSVYKQNKLDELQKKLAATTQTTKARHKPREEDTVSLGKGQGSREQIKSDIDDIIACECVYCGELMIKSIDKPFIDPQKFDQEMSSWL
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.  Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity).  May be involved in vesicle trafficking to the hepatocyte apical membrane and play a role in development of the intra-hepatic biliary tree.  May target endosomes to the pigment granule in melanocytes.  Essential for early embryonic development.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 18 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS18 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.
Protein: LSPA_DESHD
Sequence: MLIWITIGIVWAIDRVLKVLIQGNFVVGESVPVIPDFFHLTYVLNPGAAFGLLPGRTWIFIPAAIIVCAGIIYAQFKIPRQEWLMRLTLGLIGGGALGNLYDRLFIGKVVDYLDFQIWPFVFNFADSAIVVGVGLLMILMLLEDRKERKTE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IHFA_HALHL
Sequence: MSLTKADMAERLFEEVGLNKREAKELVELFFEEIRTALENGEPVKLSSFGNFELRDKNERPGRNPKTGEEIPISARRVVTFRPGQKLKSRVESYAGTREEQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: UPPP_STREM
Sequence: MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKAFMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIAVPLDDWFDVHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGCFQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGNHLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFKSLF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_POLNS
Sequence: MRPLIVIGNWKMNGSLANNQDWVKTVARGMESGMPSGRKYAVCPPFPYLQQCADLIKGHSLAFLSLGAQDASAYGSGVYTGEVAAAMLKEFGCTCVIVGHSERRQMHQEVDEVIASKALQVLDNSMTPVICVGETADERNSGRAQEIVCSQVAKQVGVLQDRLVDCLIAYEPVWAIGTGKVASAQVAQDMHRAIRLQLAEFNEDVASHVGILYGGSVKPDNAVELFAMPDIDGGLVGGASLSPQDFLAICKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_SHEPC
Sequence: MSAVIVNTVEQCGYFNRGQCQSCRHIQVPMAQQLMAKSLELQQLLKPFVAPSAAIFYPPVTGEATAFRNKAKMVVLGAAHAPVLGIVSPSGEAVSLCDCLLYPSDMQKLLHRLTQFVQQAGIPPYRVDKAKGELKFILLTRSQVRGEYLLRFVLRSHNSIERIERALPTLLAEYPQINVVSVNIQPIHMAILEGGEEIFLTENTRLEERFNDVPLFIRPKSFFQTNPQVAAQLYQTAREWVAEFAPKSLWDLFCGVGGFGLHCATKDIALTGIEIEAEAISCAQISANLMGLEKVQFMALDSTDFAQGKNAADKPDLIIVNPPRRGIGEALCQSLSEFAPKAILYSSCNPKTLAKDLEHIQGYHLTKVQLFDLFPHTDHFEVLAMLVKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.