PharMolix/UniProtQA huggingface dataset:
Protein: XDH_BOVIN
Sequence: MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRLQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCCMNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFGAACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDLNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAFKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNEKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDSKDKCGKLDPTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCKPWSLRV
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid.  Contributes to the generation of reactive oxygen species.
What are the official names of this protein?
Xanthine dehydrogenase/oxidase.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome. Secreted.
Protein: CARB_LATSS
Sequence: MPKRTDIRKILVIGSGPIVIGQAAEFDYSGTQACLALKEEGYQVVLINSNPATIMTDKTVADTVYIEPITLDFVTQILRKELPDAILPTLGGQTGLNMALELANCGILAELNIELLGTKLSAIDQAEDRELFKNLMNQLNEPIPESAIAHSLDDAQEFVKQNGFPVIIRPAFTLGGTGGGIAENAGQLKTIVKNGIALSPVGQVLVEQSIAGYKEIEFEVMRDRNDNALVVCNMENFDPVGIHTGDSIVFAPVQTLSDREVQMLRDASLKIIRALKIEGGCNVQLALDPNSERYFIIEVNPRVSRSSALASKATGYPIAKMAAKIAVGLTLDEIYNPITGTTYAQFEPMLDYVVAKIPRWPFDKFNKGDRQLGTQMKATGEVMAIGRNIEESLLKAVRSLEIGTAHLELDGLTSVSDNDLVQRIIHPQDDRLFYLAEALRRGYLIQELAELTKIDLFFLDKISHIVELEEQLRSEKGDVELLEIVKKNGFSDEKIAKTWQITPIQVRQMRQESGIQPVYKMVDTCAAEFESQTPYYYTTYEQENESLVSAKPSILVIGSGPIRIGQGVEFDYATVHCVQAIQKAGYEAIIMNSNPETVSTDFSISDKLYFEPLTLEDVLNVVELEKPEGVIVQFGGQTAINLAAPLEENGVKILGTSVANLDRAEDRDLFDQLIQELNIPQPVGKTATNAPDALTIATEIGYPVLIRPSFVLGGRAMEIVHTPEDLTHYMQEAVKVSDEHPVLIDRYLMGKECEVDAICDGQEVLIPGIMEHIERAGVHSGDSMAVYPPQNLTEDQKAAIIDYTTKLCLALDCHGLLNIQFIIQNDEVYVIEVNPRASRTVPFLSKVTQIPMAQLATQLILGSTLAELKSPTGLLPAGPLIHVKAPVFSFSKLTRVDSLLGPEMKSTGEVMGTDVTMQKALYKAFEASGMHLPSHGNVLMTVTNQDKAQALALAERFREVGYQIIATPGTTQQFKAAGIPVQQVDKINATSGDLLDKIKAGHIQLVINTTGLNEAPQVAKDSIVIRQTAIEHGIPLLTSLDTTDAILTVLESQSLLTKPL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: FB230_ARATH
Sequence: MTKVESTSGEVSEWADLNKDILELIFNKLDVMDITMGASRVCISWFLASHNKTLWNTVDLTNLQELDVSRIFNFKDKERPIFFYKHPVDHKHGLTNLLTKIISRFFLDFFEVEGSISLMNLLVEISKLSRMAPKNLFFNFNSYIQENGLKFAAEKMPNIEKLALPIWCYQNEKSLRFAFSQWKNLKTLIIAHEHSFSGRFDFKAVGESCSNLTNLKYLGRLEEYTSREIVSYLHSLKRLSLRCFLVSSIAVYRFITGLPNLTILNVSHCKNPYDYFLPIAKSIDNYVITAATQKLEKFITCPHDCMICKDRCRYSLSYLAEVWRNDEIKELEF
What are the official names of this protein?
Putative F-box protein At4g11580.
Protein: Y1387_METJA
Sequence: MFLLDPFSGISGDMFLSAMIDFVDKEDFINTIKKVIDVEIEIKKVKKCHILANKVNIIPKCINCNANTYKDIKNVIKSSDIQEDIKITALEILKILAEAESKVHNVDVENVHFHEVGNYDTIADIVGAAYIINKLNLKNNCLYKPINVGNGFVRTEHGLLPVPAPATAEILKGLKIFFSDINEELTTPTGSAIIKYINPKLAKGAFIIKEVSYGAGDKDLNLLNALRVFRVEDIKREDIVLLETNVDDISAEILGYLYEVLDGKVRDLHFIPTYMKKNRPAYTIRAIVDRDIAEEVAKIIMRETGSLGVRIFDIERITADREFKTIKLFDESVRLKVGRVNDEIISQKPEFEDLKNIAKKYGIPLKDLYKLINISQIKN
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: SYGB_ECOSE
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRLNRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_CLOTE
Sequence: MDFYSLFLIAIALSLDAFGVALCIGLNNNVDLKYKSSCAIYFGFFQFLFAIIGGYAGFLFNKYIATMPQIVGGVVICIVGIIMIKEGIENEDSCKILKPGMNIILGISVSIDAMVVGFTALNKIQSGLLILRDTLFIGIVTLFVSILAFITSKYLKKIDVIGKYADYIGGIILIFFGLKMIFF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_CHLTR
Sequence: MGMTSDSIANLLTRIRNALMAEHLYVDIEHSKMLEAIVRILKQHGFVAHFLVKEENRKRLMRVFLRYGEDRRPVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVLSTPQGVLEGSVARAKNVGGELLCLVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RSMG_ACIBC
Sequence: MHPFFQELQQGSQKLGLSLSDEALTLLLKYQDALVLWNKAYNLTAIRDPKEMLVKHLLDSLSILKDLPAGRLLDVGTGGGMPGMIIALCQPERSCVLLDSNGKKIRFLKQFIADLKLKNVIAVQTRVENQDTIDELGQFDVITSRAFASLTDFVEAARPYLHEQSIIAAMKGLIPVEEMEELKQEFSCKVIELHVPRLDEQRHLLLLQRI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBBC_SHEEP
Sequence: MPNKALITGFWSKVKVDEVGAEALGRLLVVYPWTQRFFEHFGDLSTADAVLGNAKVKAHGKKVLDSFSNGVQHLDDLKGTFAQLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKEFTPELQAEFQKVVAGVASALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-C, Beta-C-globin, Hemoglobin beta-C chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: IF1C_ILLPA
Sequence: MKEQKWIHEGLITESLPNGMFRVRLDNVDNEDLILGYVSGRIRRSFIRILPGXRVKIEVSRXDSTRGRIIYRLRNKDSNB
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNP_EXIS2
Sequence: MSQTKQTFSTELGGRPLTIEIGQLAKQANGAALIRYGETAVLATVVASKQPKDLDFFPLTVNYEEKLYAAGKIPGGFLKREGRPGENAILTSRLIDRPIRPLFPDGFRHDIQVATTVLSSDEDNSPEVAAMIGASIALSISDIPFDGPIAGVTIGRVNGEFIINPTMSQASESDIDLQVAGTKHAVNMVEAGAKEVSEQAMLEAILLGHDVIKELIAFQEEIVAAVGQEKFAYTVASFDETLVNRLKAEALAEVTTAVQVEEKQARDLAINEVISKYIDQYAADDSITEAQLAEVSGVLNKFVKTEVRRLITEDKVRPDGRGLAEIRPLDSEIGLLPRAHGSGLFTRGQTQVLSVATLGVAGDAQIIDGLGLKAEKRFMHHYNFPPFSVGEARPMRAPGRREIGHGALGERALLPVLPSETDFPYTIRLVSEVLESNGSSSQASICGSILAMMDAGVPLKAPVAGIAMGLIKEGENYSILTDIQGMEDHLGDMDFKVAGTKDGVTALQMDMKIGGITRQILEEALEQARLGRLHILEHMNSVIAEPRVELSKYAPKIVTLKINPDKIRDVIGPGGKVINGIIDETGVKIDIDQDGTVFIASTDQDGINHARQLIEDIVREVVIGEEFDGTVRRVEKFGAFVELFKGKDALVHISELALERVGQTEDVVKLGDKLKVRVTEVDDKGRVNASHKVLLVEGMSPEDRAAYDEKKKTERDSRPPRRDTGSRPPRDGQRPPRRN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_MYCTA
Sequence: MIDLKLLRENPDAVRRSQLSRGEDPALVDALLTADAARRAVISTADSLRAEQKAASKSVGGASPEERPPLLRRAKELAEQVKAAEADEVEAEAAFTAAHLAISNVIVDGVPAGGEDDYAVLDVVGEPSYLENPKDHLELGESLGLIDMQRGAKVSGSRFYFLTGRGALLQLGLLQLALKLAVDNGFVPTIPPVLVRPEVMVGTGFLGAHAEEVYRVEGDGLYLVGTSEVPLAGYHSGEILDLSRGPLRYAGWSSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCTPADAEHEHERLLGWQRQMLARIEVPYRVIDVAAGDLGSSAARKFDCEAWIPTQGAYRELTSTSNCTTFQARRLATRYRDASGKPQIAATLNGTLATTRWLVAILENHQRPDGSVRVPDALVPFVGVEVLEPVA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB003_HUMAN
Sequence: MAILMLSLQLILLLIPSISHEAHKTSLSSWKHDQDWANVSNMTFSNGKLRVKGIYYRNADICSRHRVTSAGLTLQDLQLWCNLRSVARGQIPSTL
What are the official names of this protein?
Putative uncharacterized protein UNQ5830/PRO19650/PRO19816.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_CALS8
Sequence: MIQIKLWQGRFSKDTARIFDEFNASIMVDINLFEYDVMGSVAHVKMLSKCDIIPEDEGKLIVNTLYEILNDFKEGKIEFDMSDEDVHMLIEKELIKRIGQVGKKVHTARSRNDQVVLDERLFCREKNLYLQELIKNLIDTIIKLAEENIDTIMPGFTHLQKAQPVLFSHYILAYAQMLKRDLLRFRQNFISINLNPLGSAALAGTTFDIDRFFVADQLEFDGVTENSIDTVSDRDFILEMLFNIAMLQMHLSRLAEDFIIFNTDEFRFIELDDAFCSGSSIMPQKKNPDALELIRGKTGRTFGNLIGLLTVLKALPLSYNKDMQEDKEFLFDSIDTAEKSLIIVNEILKTLKVNKENMLLACKSGFINATDLADYLVTKGVAFRDAHFVVGNIVKYCIENNKSLEELSTEEFKRFCDKIEEDVFKFISLENCIKRRKSYGATSPELVKKQIENLKEFLRAYE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT19_MOUSE
Sequence: MIITTWIMYIFARKTVGLPFPPRVNSDIEVEESEAVSVVQHWLNKTEEEASRSIREKMSINDSPTHGHDIHVTRDLVKHHLSKSDMLTDPSQEVLEERTRIQFIRWSHTRIFQVPSEVMDDVMQERIDQVRRSVSHLMCDSYNDPSFRTSCSEC
What is the function of this protein?
Essential for sperm motility and male fertility (PubMed:26265198).  Plays an important role in sperm motility by regulating the organization and function of the mitochondria and is also required for correct sperm midpiece assembly (PubMed:26265198).
What are the official names of this protein?
Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion. Cell projection, cilium, flagellum. Note=Localizes to the midpiece of the sperm flagellum.
Protein: SPAC_BACIU
Sequence: MERGTVSRIEVEIVKEMARQISNYDKVLEIVNQKDNFRSIGEVPLIPWKSTALSHGIPGICMLYGELHAHFPEEGWDDIGHQYLSILVNEIKEKGLHTPSMFSGAAGIGLAAICLSQRFTYYNGLISDINEYLAETVPQLLTEFDQRQVCMSDYDVIEGVSGIANYLLLFQEDKAMGDLLIDILKYLVRLTEDIIVDGEKVPGWHIPSQHQFTDIEKKAYPYGNFNMGLAHGIPGPICVLSSALIQGIKVKGQEAAIEKMANFLLEFSEKEQDSLFWKGIISFEEYQYGSPPNAVNFSRDAWCYGRPGVCLALVKAGKALQNTELINIGVQNLRYTISDIRGIFSPTICHGYSGIGQILLAVNLLTGQEYFKEELQEIKQKIMSYYDKDYIFGFHNYESMEGEEAVPLQYVGLLDGAVGVGLGVLNMELGSKTDWTKALLI
What is the function of this protein?
Could be implicated in the processing or the export process of the subtilin lantibiotic.
What are the official names of this protein?
Subtilin biosynthesis protein SpaC.
What is the protein family that this protein belongs to?
To S.epidermidis EpiC and L.lactis NisC.
Protein: CPT2_MOUSE
Sequence: MMPRLLLRDWPRCPSLVLGAPSRPLSAVSGPAEYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLRAGLLEPEVFHLNPARSDTDAFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPKPSRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILSDSSPVPEFPLAYLTSENRDVWAELRQKLIHGGNEETLRKVDSAVFCLCLDDFPMKDLVHLSHTMLHGDGTNRWFDKSFNLIVAKDGTAAVHFEHAWGDGVAVLRFFNEVFRDSTQTPAIAPQSQPAATDSSVSVQKLSFKLSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVREPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSGRNAREFLHCVQKCLEDMFDALEGKAIKT
What is the function of this protein?
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites.  Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion.  Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.
What are the official names of this protein?
Carnitine O-palmitoyltransferase 2, mitochondrial, Carnitine palmitoyltransferase II, CPT II.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: F16PA_BRASO
Sequence: MAREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSGIDEGAATVNTDGDIQKALDIVADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAIDPLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRAAGFFVYGPQTCLVLAIDRRVDLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRDFNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASSGRARILELSARSPHQRAPLIMGDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA2_XANCP
Sequence: MGLTDTQQAILALIAERIETDGVPPSQTEIARAFGFKGVRAAQYHLEALEQAGAIRRVPGQARGIRLAGAAAHARAAPAEEPVRDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: S11IP_XENTR
Sequence: MPSEVPESLVQALAQILHEHGDKVLDGSRILALLTPCLQVVTRLFEQLFPRGPGTGFQALPAHPADSVPILRAQFMLDMLQKTPSLKLVHPAECPRQFDVNIFPFKSLRSLELRCLPPHCLRGLRSVYSQLEVLTCYRCVSSLEEVIALCGGDLSSALPWLVLHTLDFSYNTLKNLDGSLELLNSLKILDLSHNQITECGSYLKVLSELQYLNLGYNHLTAVPELSVGNTAKLHSLILKHNQLSGTSGLENLPNLQHLDLSYNLLLEHSQLSGLARLHNLKQLFLEGNPLYFQKDYRALTAQHLSHKASDNVLLDGKLLSSSEIMNAQAFGEKVRLQPSSSATESSCTGDLTDSYSAAEKSAPRLPRKKSRVKVRTASISERSDSEYERRGQPIVLQHQREIERTDSFREQYGEDWLQYRPHLEGELDPEYVNRPHSPPPRASPSPTAPSSVPKQKSPVPAPEPSPSPKSGHVAPDDQLMEKAEEGLEEHLWGLQEAKKPNEEEGLIGGALCSPVVVCPVLNGQPRNPDWPWVFLRITLHFLLEMDPERGRILLKRELRSLRGIQTSLAPWKCNGEEQELPLLTLSFDSVCEEKQTVNYIVLDNSPESSVTTLLDLLRPMLERNLREKAESQDELTRMQCLKCKAEFRNEVDGGDIYSPESLQQGKEPTAGLHRNHTGDASCPSCGSLHIILAPLNPTGETSTPLRPLSAEPPQGDDGGGGLAAKSFYLSEDEDSSETDSSPNTAPSEAESTIFYSFDTEGQDQQSAQDTGRSSLTGSYKYTALNQSGALSQDGWQISPGPASTLDFRLVDHRLKLYLDMEVLNGDMEEFRCCMKVPVIRFGKVSEFWAVVAVSNQKIYFLEITGEIRDNPSDWLQPIESQSLTSLARLHVGLQEHSLHLGFGGSGGAYTLLTRNQQHCRVFHKHMLDVLAELPARYLGNIQQSSEEPITPQHRLWPFLQDKVGAPESNAPPRFLYVPLFFLREDIVSPNADSPCANANSQLPLLNTASPAALIQGAAAAAPLSLLVTRTHMYLLEEDHQWLPDTLDTELPDSVQMKEKQPISNISSVHLFQSATLHLRIHLYNETQQNESAWLLWTEDPDRTREIVEWLREPWEAEYHIHFNPVTHNT
What are the official names of this protein?
Serine/threonine-protein kinase 11-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the STK11IP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_YERPY
Sequence: MFYPDQFDVIIIGGGHAGTEAAMAAARMGRQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDALGGLMAKATDLAGIQFRILNASKGPAVRATRAQADRVLYRLAVRTALENQPNLMIFQQPVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLENYSGGRAGDPPSISLSQRLRELPLRVNRLKTGTPPRIDARTIDFSQLTPQLGDTPIPVFSFLGNAEQHPEQMACHITYTNEKTHEVIRNNLDRSPMYAGIIEGIGPRYCPSIEDKVMRFADRNSHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMKGLENARIIRPGYAIEYDFFDPRDLKPTLESKYIQGLFFAGQINGTTGYEEAAAQGLLAGLNAGRFANEEDGWSPRRDEAYLGVLVDDLSTLGTKEPYRMFTSRAEYRLMLREDNADLRLTETGRKLGLVDDIRWAHFSQKVEQIEKERQRLRDIWVHPHSENVSEINALLKAPLSKEANGEELLRRPEIDYRLLTSLTSFGPALTDPQSADQVEIQVKYEGYITRQQEEIEKQLRNENTLLPVDLDYQQVSGLSNEVIAKLNDHKPSSIGQASRISGITPAAISILLVWLKKQGLLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFB2_YEAST
Sequence: MSDYSLKHSVTQYLEEIPQQVQNRLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLLDLDKWVNSNGKLQFQNAIKSMKSLHLLIPNKSSGTLMINLNPTFKISLRNALTGGEVQNSFGVVVEENVVSLDLLDEYSANKWETILHFMVGTPLAKIPSEKVLNLLKHSKLMEEVNSTGEFKITNEGFQFLLQEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKIDALSETQRIMLQDMRDYGLVFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDSVLRQNREEPSVNEDGANGKSTTDITTSDDLNKAGLKNQDIPDGSLIVETNFKIYSYSNSPLQIAVLSLFVHLKARFVNMVLGQITRESIRRALTNGITADQIIAYLETHAHPQMRRLAEEKLEKKLELDPNCKEPLQVLPPTVVDQIRLWQLELDRVITYEGSLYSDFETSQEYNLLSKYAQDIGVLLWKDDKKKKFFISKEGNSQVLDFAKRKLKKKQ
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB2, TFIIH subunit TFB2, RNA polymerase II transcription factor B 52 kDa subunit, RNA polymerase II transcription factor B p52 subunit, RNA polymerase II transcription factor B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TFB2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RYL1_YARLI
Sequence: MSHSQRTYDLLIKLLLIGDSGVGKSCLLLRFCEDQFTPSFITTIGIDFKIRTIDIGNQRVKLQVWDTAGQERFRTITTAYYRGAMGILLVYDVTDEKSFNNIENWYQNVQSYANEGVELILVGNKCDLDEKRVVSTEQGQALADKFGIPFLEASSKTNINVEECFYSVATRIRDTVAKTKGNESGSGGINIAEGEENSASKCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-like GTP-binding protein RYL1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: AKTIP_AEDAE
Sequence: MTLDSYDKLLGTVLQEYKILSEYKRLQNEDLGGLYVIPSFENSFLWFGVIFVRSGPYKDGVFRFTVSLPDKFPNDATVPTVVFQSETFHPLIDPYNGTLELAEAFPKWKSGENHVWQLLKFIQYIFASFDEYMSLAEQSANNVAYELYGQNRPEFLRKVEECVRLGQSRLYDPAPVQDRNYIVFDRFDRETHGPVLESLKQGKANEVTTPPSSGLSWVKEGVFQPLSKQG
What are the official names of this protein?
Protein crossbronx homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: SEC11_YEASB
Sequence: MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Secretory protein 11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TRPD_VIBVU
Sequence: MEAIINKLYQQASLTEQESQQLFDTIIRGELDPILMASALTALKIKGETPDEIAGAAKALLANAQPFPRPDYDFADIVGTGGDGHNTINISTTAAFVAAACGLKVAKHGNRSVSSKSGSSDLLDSFGINLAMSAEDTRSAVDNIGVAFLFAPQYHSGVKHAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSQELVRPIAETMLKMGMKRAAVVHGSGLDEVAIHGDTLVAEIKDGVIHEYTLTPADFGVNTHPLEAIKGGDPEENKAIITHLLTGKGTEAQLSAVAVNVALLMRLFGHEDLKANTQQAIDVMNSGKAYQLVEKLAQHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CLPX_ANOFW
Sequence: MFKFNDEKGQLKCSFCGKTQEQVRKLVAGPGVYICDECIELCTEIVQEELGSEEEVEFKDVPKPKEIRDILDEYVIGQDEAKKALSVAVYNHYKRINSNSKIDDVELAKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGLEPIIKRRLGKKVIGFSSDAQAEVEEKDLLSKVLPEDLLKFGLIPEFVGRLPVITSLQPLDEDALVDILVKPKNALVKQYEKMLELDDVELEFEEEALREIAKRAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITAETVRGEKAPLLILHDGTIIEYERKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.