PharMolix/UniProtQA huggingface dataset:
Protein: IF2_TRIV2
Sequence: MNNGKVRIYELSKELNLDNKELLAICDQLNIAVKSHSSTISESEAESIRAAAEKLAATNGTSKKELNTTSHKPNSAPAGSRNRPAPPQKQQQILEIRKPKILRNTTSNAPEASVANNQIASSEANSPAPPRPFATPVSPMKPTAPSRPVPRNLSETPQKPAAPEAEPEAQSQAPAKIAVEKPEKSAQPRPGKPERQPKPQLVAPPSRPTAEKLDLSEITGAPGEKPILKRDRPRREDERDQAKPRVAKPAQGETSSAPVQKQARPAQGPVKPEQRVNRPGAPSGDGIRPQRPVRPSVDAAPVATPPRGVPGGRGEVGDTAAIAPDLLDLKRPTPPRLAKGGKKWQEEEIIDEIKEKAGKAGVKGKRVKPLVEDDFEDEDLLDEEGLEIPATVQVSLSIARPPKPKAARAATAATAAPISSPTTRGKRSSHNNRDQNRRQETEVKRERPEKVAVTGPMTVQELADLLAVADTEIVKILFMKGMAVSITQNLDIPTITLVGKELEIEVETAEPEAEARKVTEMIEVGDLEHLLRRPPVVTIMGHVDHGKTTLLDSIRKTKVAAGEAGGITQHIGAYHVDIVHDGKEQQIVFLDTPGHEAFTAMRARGARVTDIAVLVVAADDGVRPQTVEAISHAQAAGVPIVVAINKIDKEGAQPDRVKQELTQYGLTPEEWGGETIMVPVSAIKGENLDTLLEMILLVAEVGELSANPDRNARGTVIEAHLDKAKGAVATLLIQNGTLHVGDILLAGSAFGKVRAMVDDRGRRVDIAGPSFAVEVLGLSDVPAAGDEFEVFDNEKEARALASDRADKQRLSRLLQGRVTLTTLSAQAQEGELKELNLILKGDVQGSVEAIVGSLKQIPQNEVQIRMLLTAAGEITETDIDLAAASGAVIIGFNTTFASGARQAADEAGVDVREYNIIYKLIEDIQGALEGLLEPELVEEPLGQTEVRAVFPVGRGAVAGCYVQSGKLVRNCKVRVRRAGKVIYEGVLDSLKRMKDDAREVNAGYECGIGVDKFHDWAEGDIIESYQMVTKRRTLALTR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_SALSA
Sequence: MAITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGALLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLIPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVAYYSGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGSIKWETPLLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGAFVHWFPLFTGYTLHSTWTKIHFGIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNTISSIGSLISLVAVIMFLFILWEAFAAKREVASIEMTSTNVEWLHGCPPPYHTFEEPAFVQVQAS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRAY_BURM1
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTEMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU3_ACRCH
Sequence: MTTTYKILVLPGDHIGPEIMAEAIKVLTTIETHRPNLHFNLTTDLVGGTSIDTHGVPITQSVLDAAKASDAVLFGSIGGPEWAGVHPTPESGLLQLRQHLDAFANLRPCEFLVPSLVGASPIREHVVKGTRFIVVRENCGGAYFGEKKEEEDVASDLWVYTRPEIERLARVSAAVARIMGRSEDDNQAATVWSADKANVLASGRLWRRITSDIFAKEFPDITLQHQLADSMAMLMVRDPRRFNGVIHTDNTFGDILSDISGAITGTLGLMPSASLCGVPGEGHRSNGIYEPVHGSAPDISGKGLANPVAQILSVAMMLRYSMGLEKEATAVERAVVKVLDAKSEGGLEIRTGDLGGRATCSQVGDAVCEVLGPLLQGKKA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DC1I1_HUMAN
Sequence: MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1.  May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
What are the official names of this protein?
Cytoplasmic dynein 1 intermediate chain 1, Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
Protein: POT3_ARATH
Sequence: MADRRNRCNQILLLAYQSFGLVFGDLSISPLYVYKCTFYGGLRHHQTEDTIFGAFSLIFWTITLLSLIKYMVFVLSADDNGEGGIFALYALLCRHARFSLLPNQQAADEEISTYYGPGDASRNLPSSAFKSLIERNKRSKTALLVLVLVGTSMVITIGVLTPAISVSSSIDGLVAKTSLKHSTVVMIACALLVGLFVLQHRGTNKVAFLFAPIMILWLLIIATAGVYNIVTWNPSVYKALSPYYIYVFFRDTGIDGWLSLGGILLCITGTEAIFAELGQFTATSIRFAFCCVVYPCLVLQYMGQAAFLSKNFSALPSSFYSSIPDPFFWPVLMMAMLAAMVASQAVIFATFSIVKQCYALGCFPRVKIVHKPRWVLGQIYIPEINWVVMILTLAVTICFRDTRHIAFAFGLACMTLAFVTTWLMPLIINFVWNRNIVFSVLFILFFGTIELIFVASALVKIPKGGWITLLLSLFFTFITYVWHYGSRKKYLCDQHNKVPMKSILSLGPSLGIIKVPGMGLIYTELASGVPATFKHFLTNLPAFYQVVVFVCCKTVPIPYVPQKERYLIGRIGPKTYRMYRCIIRAGYKDVNKDGDDFEDELVMSIAEFIQLESEGYGGSNTDRSIDGRLAVVKASNKFGTRLSRSISEANIAGSSRSQTTVTNSKSPALLKLRAEYEQELPRLSMRRMFQFRPMDTKFRQPQVKEELFDLVNAKDAEVAYIVGHGHVKAKRNSVFVKQLVVNVAYSFLRKNCRSPGVMLNIPHICLIKVGMNYYL
What is the function of this protein?
High-affinity potassium transporter required for tip growth of root hairs.
What are the official names of this protein?
Potassium transporter 3, AtKT3, AtKUP4, AtPOT3, Tiny root hair 1 protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RGLG2_ARATH
Sequence: MGTGNSKENWRQSSFRSTSASSASPSSSSWASQQSYPQYGAESYNYPPPPSYAQPPEYTQPPPPLYSTQPYSAPSYSAPPSQSYGSDNKKRLERKYSKISDDYSSLEQVTEALARAGLESSNLIVGIDFTKSNEWTGARSFNRKSLHFIGSSPNPYEQAITIIGRTLAAFDEDNLIPCYGFGDASTHDQDVFSFNSEDRFCNGFEEVLSRYKEIVPQLKLAGPTSFAPIIDMAMTIVEQSGGQYHVLVIIADGQVTRSVDTENGQLSPQEQKTVDAIVQASKLPLSIVLVGVGDGPWDMMREFDDNIPARAFDNFQFVNFTEIMAKNKAQSLKETEFALSALMEIPQQYKATIELNLLGRRNGYIPERFPLPPPMRGGSSSYNSPKPSRLPSFKPSVPPHPTEGYHVRSSPVPPPTSSASDNQLCPICLSNPKDMAFGCGHQTCCECGPDLQMCPICRAPIQTRIKLY
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains.  Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653).  Mediates ubiquitination and subsequent proteasomal degradation of ERF053 in response to drought stress.  Acts as a negative regulator of drought stress response (PubMed:22095047).
What are the official names of this protein?
E3 ubiquitin-protein ligase RGLG2, RING domain ligase 2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Nucleus. Note=Translocates to the nucleus under salt stress.
Protein: RABV_DICDI
Sequence: MSNKKNNIIKIMILGEKEVGKSSLLIRATKDEFNSQYIPTIGIDFDYKIMEIKGEKYKLQIWDYVSHDHINVFNKQVLSNTKIILLLFDLTNKSSFDSINNWLLKLDQSNKDNSIQIFLVGTKSDLISNRQVSLLDIQSKFIQNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNLQYFEISSKDNNNVEFLFTSVIDYYLLKAQPKFEEEIKNKKKKLKITVSWFDI
What are the official names of this protein?
Ras-related protein RabV.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: RBSD_LIMRJ
Sequence: MKKTGIINSEVSAVVANMGHMDWLSIGDAGMPVPFGTKKIDLAVDKELPSFMDVLNNVLKEMKVQKIYLAEEIKDQNPAQLENIKKALPDVEVAFMPHSELKKSLTKTHAFIRTGEMTPYSNIILESGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL16_CHLAE
Sequence: MDYSFDTTAEDPWVRISDCIKNLFSPIMSENPGHMPLQPNASLSEEDGTQGHPDGNPPKLDTANGTPKVYKSADRSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGPHIRASSSSSSIKQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGKHEGGRFSGLLGRGAAPTLVPQQPEQVLPSGSPAATEARDPGVSESPPPGLQPNQKTLPTGSDPLLRLLSTQTEKSQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSLSCAQTPCIPKEGASPTSSSNEDSAANGSAETSASDTGFSLNLSELREYTEGLTEAKEDDDGDHSSHQSGQSVISLLSSEELKQLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPRQAVIVTRKLTAESMPDLNSTTDSAASASAASDVSVESSAEATVYTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQPKETTAAADS
What is the function of this protein?
Pro-interleukin-16 is involved in cell cycle progression in T-cells.  Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene.  May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity).
What are the official names of this protein?
Pro-interleukin-16.
What are the subcellular locations of this protein?
[Interleukin-16]: Secreted. SUBCELLULAR LOCATION: [Pro-interleukin-16]: Cytoplasm. Nucleus.
Protein: GUC2F_MOUSE
Sequence: MFLGPWPFSRLLSWFAISSRLSGQHGLPSSKFLRCLCLLALLPLLRWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDKTFDRSYSFEYVILNEDCQTSKALASFISHQQMASGFVGPANPGFCEAASLLGTSWDKGIFSWACVNHELDNKHSFPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWMHTANRVSSALRSQGLPVGVVLTSGRDSQSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPYDVLLYSLPYKHSPYQVLRNNPKLREAYDAVLTITVESHEKTFYEAYAEAAARGEIPEKPDSNQVSPLFGTIYNSIYFIAQAMNNAMKKNGRASAASLVQHSRNMQFYGFNQLIKTDSNGNGISEYVILDTNGKEWELRGTYTVDMETELLRFRGTPIHFPGGRPTSADAKCWFAERKICQGGIDPALAMMVCFALLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFINPHFGSKRGSRASVSFQIISEVQSGRSPRLSFSSGSLTPATYENSNIAIYEGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEEPSEEELLWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP
What is the function of this protein?
Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (By similarity).  Plays an essential role in phototransduction, by mediating cGMP replenishment.  May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (PubMed:17255100).
What are the official names of this protein?
Retinal guanylyl cyclase 2, Guanylate cyclase 2F.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Photoreceptor outer segment membrane; Single-pass type I membrane protein.
Protein: ETXE_STAAU
Sequence: MKKTAFILLLFIALTLTTSPLVNGSEKSEEINEKDLRKKSELQRNALSNLRQIYYYNEKAITENKESDDQFLENTLLFKGFFTGHPWYNDLLVDLGSKDATNKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWIDGKQTTVPIDKVKTSKKEVTVQELDLQARHYLHGKFGLYNSDSFGGKVQRGLIVFHSSEGSTVSYDLFDAQGQYPDTLLRIYRDNKTINSENLHIDLYLYTT
What is the function of this protein?
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules.  In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (PubMed:24194959).  Causes also the intoxication staphylococcal food poisoning syndrome (PubMed:20394711).
What are the official names of this protein?
Enterotoxin type E, SEE.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL24_ERWT9
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKIIVEGINLVKKHQKPVPALNQPGGIVEKEAALQISNVALFNSATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CYB_CEPRU
Sequence: MTNIRKTHPLLKIVNNAFIDLPAPSNISSWWNFGSLLGICLVLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTYMETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILVLMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLVLMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NDVA_BARBK
Sequence: MSLFRTYVRVLSYLNQEKNAFLLICTANITLAIITIAEPILFGHVIDTIADKSDTLVTLAVWMCFGISNIIAYVLVARGADRLAHRCRLTVLEKSFARIISMPLIWHQQRGTSHALHTLLRATDSMSSIWLEFMRQHLSTFVALFVLVPVTFKMNWRLSIVLMVLAILYILIARLVMQKTKNGQAAVEHYHHNLFKHITDSISNVSIVQSYNRITEETSALHQHTNNLLSAQTPVLNWWALASGLNRMASTISIVCVLLLGAFFVIKGQLSVGEVVTFVGFSQLMIGRLDQISGFINLAVSSQAKLQEFFDMEDSTFQTNEPANLPSLPNVKGAIQFHHVTYEFPNSSQGVFDISFEVKAGQTVAIVGPTGAGKTTLINLLQRVYDPTVGYISIDGININSINRESLRKALATVFQDAGLFDRTIRDNISIGKTGATDEELYEATKTASAHDFILKKSKNYDTLVGERGSQLSGGERQRLAIARAILKNAPILILDEATSALDVETEIRVKNAIDCISQNRTTFIIAHRLSTIRNADLVLFLDQGRLIEKGSFQELINKDGHFYKLLKAGGLTINQPATKEKDDNIIPLRKAMAL
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TVA10_HUMAN
Sequence: MKKHLTTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTVSPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYTATLDADTKQSSLHITASQLSDSASYICVVS
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 10.
What are the subcellular locations of this protein?
Cell membrane.
Protein: H16A5_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKPLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.5, HNTX-XVI.5, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RLP39_ARATH
Sequence: MSELLFRLNFLLLLLLSCVSLASSFFSFNDPVVGLGACGPHQIQAFTQFKNEFDTHACNHSDSLNGVWCDNSTGAVMKLRLRACLSGTLKSNSSLFQFHQLRHLYLSYNNFTPSSIPSEFGMLNKLEVLFMSTGGFLGQVPSSFSNLSMLSALLLHHNELTGSLSFVRNLRKLTILDVSHNHFSGTLNPNSSLFELHNLAYLDLGSNNFTSSSLPYEFGNLNKLELLDVSSNSFFGQVPPTISNLTQLTELYLPLNDFTGSLPLVQNLTKLSILHLSDNHFSGTIPSSLFTMPFLSYLDLGGNNLSGSIEVPNSSLSSRLENLNLGENHFEGKIIEPISKLINLKELHLSFLNTSYPINLKLFSSLKYLLLLDLSGGWISQASLSLDSYIPSTLEALLLKHCNISVFPNILKTLPNLEFIALSTNKISGKIPEWLWSLPRLSSVFIEENLFTGFEGSSEILVNSSVRILNLLSNNLEGALPHLPLSVNYFSARNNRYGGDIPLSICSRRSLVFLDLSYNNFTGPIPPCPSNFLILNLRKNNLEGSIPDTYYADAPLRSLDVGYNRLTGKLPRSLLNCSALQFLSVDHNGIKDTFPFSLKALPKLQVLILHSNNFYGPLSPPNQGSLGFPELRILEIAGNKFTGSLPPDFFENWKASSLTMNEDQGLYMVYNKVVYGTYYFTSLEAIDLQYKGLSMEQNRVLSSSATIDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSLANLKKIESLDLSSNQLSGTIPNGIGTLSFLAYMNVSHNQLNGEIPQGTQITGQPKSSFEGNAGLCGLPLQESCFGTNAPPAQHPKEEEEEEEEEEQVLNWKGVGIGYGVGVLLGLAIAQLIASYKPEWLVFLFQSRNH
What are the official names of this protein?
Receptor-like protein 39, AtRLP39.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HIS6_PSEP1
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAADRFGSQCIVVAIDAKKVSGPGEAPRWEIFTHGGRKPTGLDAVEWAKKMEGLGAGEILLTSMDQDGMKNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGILEGHASAVLAASIFHFGEYTVPEAKAYMASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGA10_ORYSJ
Sequence: MKTKTAAAATCLVALLVVVLAEAAGVGGTTVTYNDRSLVIDGERRIIISGSIHYPRSTPEMWPDLIKKAKEGGLDAIETYVFWNGHEPHRRQYNFVGNYDIVRFFKEIQNAGLYAILRIGPYICGEWNYGGLPAWLRDIPGMQFRLHNAPFENEMEIFTTLIVNKMKDANMFAGQGGPIILAQIENEYGNIMGQLNNNQSASEYIHWCADMANKQNVGVPWIMCQQDSDVPHNVVNTCNGFYCHDWFPNRTGIPKIWTENWTGWFKAWDKPDFHRSAEDIAFAVAMFFQKRGGPYITTSYDYDAPLDEYGNLRQPKYGHLKDLHSVIKSIEKILVHGEYVDTNYSDKVTVTKYTLDSTSACFINNRNDNMDVNVTLDGTTHLLPAWSVSILPDCKTVAFNSAKIKAQTTVMVNKAKMVEKEPESLKWSWMRENLTPFMTDEKGSYRKNELLEQIVTSTDQSDYLWYRTSINHKGEASYTLFVNTTGHELYAFVNGMLVGQNHSPNGHFVFQLESPAKLHDGKNYISLLSATIGLKNYGPLFEKMPAGIVGGPVKLIDNNGKGIDLSNSSWSYKAGLAGEYRQIHLDKPGCTWDNNNGTVPINKPFTWYKTTFQAPAGEDTVVVDLLGLNKGVAWVNGNNLGRYWPSYTAAEMGGCHHCDYRGVFQAEGDGQKCLTGCGEPSQRFYHVPRSFLKNGEPNTVILFEEAGGDPSHVSFRTVAAGSVCASAEVGDTITLSCGQHSKTISAINVTSFGVARGQCGAYKGGCESKAAYKAFTEACLGKESCTVQITNAVTGSGCLSNVLTVQASC
What are the official names of this protein?
Putative beta-galactosidase 10, Lactase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.