PharMolix/UniProtQA huggingface dataset:
Protein: RS5_BOVIN
Sequence: MTEWETAAPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CYB_TRYBB
Sequence: MLYKSGEKRKGLLMSGCLYRIYGVGFSLGFFIALQIICGVCLAWLFFSCFICSNWYFVLFLWDFDLGFVIRSVHICFTSLLYLLLYIHIFKSITLIILFDTHILVWFIGFILFVFIIIIAFIGYVLPCTMMSYWGLTVFSNIIATVPILGIWLCYWIWGSEFINDFTLLKLHVLHVLLPFILLIILILHLFCLHYFMSSDAFCDRFAFYCERLSFCMWFYLRDMFLAFSILLCMMYVIFINWYFVFHEESWVIVDTLKTSDKILPEWFFLYLFGFLKAIPDKFMGLFLMVILLFSLFLFILNCILWFVYCRSSLLWLTYSLILFYSIWMSGFLALYVVLAYPIWMELQYWVLLLFLLIVCRLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS51_LEGPA
Sequence: MSSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTLNFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHKIPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKRLADTLYDGQAISAVIKDENMYGCQFHPEKSGEVGLSIIQQFLQI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ALISL
Sequence: MFEKPVVKSFQYGNHTVTLETGVMARQATAAVMASMDDTSVFVSVVAKKEAVAGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLTARLIDRPIRPLFPSAFKNEVQVIATVVSINPDVNPDMITMIATSAALSIAGVPFNGPIGAARVGHINGELVLNPSNTELANSKLDLVVSGTEAAVLMVESEADNLSEEEMLSAVVFGHDQQQVVIKAINEFAAEVATPSWNWEAPVVNAELKAQVAELAETRLSEAYQITEKMARYEQVGAIKSEVVAALLVQNEALDEREIRGMLGALEKNVVRSRIIAGHPRIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTQRDAQIIDSLMGEKKDHFLLHYNFPPYCVGETGFVGSPKRREIGHGKLAKRGIAAVMPSVEEFPYTVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKASVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTNAGITALQMDIKIEGITKEIMQIALNQAQGARKHILTVMDEAISGAREDISQYAPRIHTMKISSDKIKDVIGKGGAVIRALCEETGTTIEIEDDGTIKIAATEGAAAKEAIRRIEEITAEVEVGKIYPGKVMRIVDFGAFVTVLGPKEGLVHISQIAEERIEKVADHLQVGQEVQTKVLEIDRQGRIRLSIKEATAELNPVAATEVKDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIP_CHLAE
Sequence: MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDNEGTVLDDSRVRGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLGNIAVGKDPLEGQRHCCGVAQMHEHSSLGHADLDALQQNPQPLVFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVAEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH
What is the function of this protein?
Cellular negative regulator of the hepatitis B virus (HBV) X protein.
What are the official names of this protein?
AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, p38.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEBV_ECOL6
Sequence: MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAWDAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA
What are the official names of this protein?
Uncharacterized protein YebV.
Protein: SYK_YERP3
Sequence: MSEQKPQVAEQAQELNSELQARREKLAVLRGKGIAFPNDFRRENLSDQLHAEFDSKENEELEALNIDVTVAGRMMTRRIMGKASFVTLQDVGGRIQLYVSRDDLPEGVYNEEFKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGLADQETRYRQRYLDLIANDESRHTFKVRSQVMSGIRSFMVEKGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLIVLTEELFRTLTETILGSSVVQYGEQTFDFGKPFAKLTMKEAICKYRPETNVADLDDMDKAVAIAESLGIKVEKSWGLGRIQCEIFEETAESHLIQPTFITEYPAEVSPLARRNDDNPFITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQVSAKEAGDDEAMFYDEDYITALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP7S_CUCMA
Sequence: QKVVGIDLGTTNSAVAAMEGGKPTIVTNAEGQRT
What is the function of this protein?
Interacts with newly imported chloroplast proteins to assist in their maturation.
What are the official names of this protein?
Stromal 70 kDa heat shock-related protein, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y692_METTH
Sequence: MILELIIVLVLLVLAFKSLKILRPYEKGVVERLGKYQRTVESGLVVIIPFIEAIKKVDMREQVVDVPPQEVITKDNTVVVVDCVIFYEVVDPFNAVYNVVDFYQAITKLAQTNLRNIIGDLELDQTLTSREMINTQLREVLDEATDKWGTRVVRVEIQRIEPPGDIVEAMSKQMKAERMKRAAILEAEGYKQSEIKRAEGDKQAAILEAEGKAEAIKKVADANKYREIAIAEGQAKAILSVFRAMHEGDPTNDIIALKYLEALEKVADGRATKILLPVEATGILGSIAGISEMLSDPEDKGVSEVETESQPAEKPEKH
What are the official names of this protein?
Uncharacterized protein MTH_692.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COX2_TUPGL
Sequence: MAYPLQLGFQDASSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEELTFDSYMIPTLDLKPGDVRLLEVDNRVVLPMEIPVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLISTRPGLFYGQCSEICGSNHSFMPIVLELVPLKHFENWTTTML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ANMK_CUPMC
Sequence: MPASPQSSEMFIGLMSGTSMDGADGVLVDFSGAQPAVLAAAHTPFPAPLREAFGALQQPGDDEIHREALASNGLARVYADCVATLLRTASVTADRVAAIGAHGQTIRHRPGQYDGTGYTRQSQHPALLAELTGIDVVADFRSRDVAAGGQGAPLVPAVHAALFGAADETRVVCNIGGISNISILPAAGTGRPVTGFDCGPGNALLDDWIHRHRGTPYDDGGAWAASGKVDESLLDQMLAEPYFRALPPKSTGRDLFHPGWLQSLLDTYGNAQPQPVDIQATLATLTATAIAQDVQRYAPEARRLIVCGGGAHNDFVMTTMANQLPGVLVQTTGDFGVPVSQVEAIAFAWLARQCTRRAPGNVATVTGAAGPRVLGAIYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DTX17_ARATH
Sequence: MEDGVTPPLLITEKDTTMIRVKEEVKKQLWLSAPLIGVSLLQYSLQVISVMFVGHLGSLPLSAASIATSFASVTGFTFLLGTASALETLCGQAYGAKLYGKLGIQMQRAMFVLLILSVPLSIIWANTEQILVLVHQDKSIASVAGSYAKYMIPSLFAYGLLQCINRFLQAQNNVFPVFVCSGITTCLHLLLCWLFVLKTGLGYRGAALAISVSYWFNVILLSCYVKFSPSCSHSWTGFSKEAFQELYDFSKIAFPSAVMVCLELWSFELLVLASGLLPNPVLETSVLSICLNTSLTIWQISVGLGGAASIRVSNELGAGNPQVAKLAVYVIVGIAVAEGIVVVTVLLSIRKILGHAFSSDPKIIAYAASMIPIVACGNFLDGLQCVLSGVARGCGWQKIGACVNLGSYYLVGVPLGLLLGFHFHIGGRGLWLGIVTALSVQVLCLSLVTIFTNWDKEAKKATNRVGSSDDKDGDVQ
What are the official names of this protein?
Protein DETOXIFICATION 17, AtDTX17, Multidrug and toxic compound extrusion protein 17, MATE protein 17.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SQS1_LODEL
Sequence: MPKRGNRRTRGSRGGSRGGSRNLLKNRTRGNKRKSPSSNTYNRLSSSQYQELMDLDSIYIPNGEMAEVGRNMGRRRYGKLAEEAAYTESHRYEDFASKTFRNRPIEFIKAKEVYDPNVILHKLTQEKKTQYGDIIDEEFKSISLDDSEADSEADDDDEEEEEEEEEEKDGQEMENENETDDANEEADEQSSELWNDEEEGDSQEDWDEEELRKVLDKKLVQLQKELDLEQDVGIVEKNEKDIIDKEDKESDVDDSILNADKENSEQFVNIGKNQSEIESEDEDGDEEEEQDLDENNDFEDDSDDDLDDASIEDINGEEFAKQNDVSSISYLDENNIYSEKLSRDESLDSIPGSKNVDNSSSLEEITVKSKPKDLVKNATNNFINCNERTGKDKPESEPEYGFLEEDYEFDVSKIEVSNVRFGISNQYYVKCAELTGTTVDEFFWFDEEDVIDYVLANGVKEHRLAKFLSFVTKGMVGGNESESQEDLDAFTIDVNGLDDDDESDDDEDDDEDEDENKFASGQDDYPYDSEDGLEDLIAYTRNSTQGLVPMLDRDFSRNIPAKSRSTFDDLDIDPDLQSSLTRQLKNYNHNKREKRKARKDREVEEAVLRNDMLIKYPEKILIKEIRAEFEALLKDESRHSMSFPTLDSHGHHTIKNMADCYHMTTDKCGKQGVRHYLKVSKTKSTFKYFPNYKRVNAIMRGRPIFHRIDRKPNPKDKKTKTISGRGSDSGGRAKFKEGDIVGAEAPEIDQNNLGRQMLERLGWSKGMGLGLSGRGINEPIVAKVKMSKTGIK
What is the function of this protein?
May be involved in splicing.
What are the official names of this protein?
Protein SQS1.
What is the protein family that this protein belongs to?
Belongs to the SQS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPEA_SHIF8
Sequence: MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPVEDAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQFRDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: YIPF7_MOUSE
Sequence: MSNPEQYDMGFYQSNYIIDNQEPSCNDSNAYGNVYGYREPQATEQPSSPAPPEMFLPSDYGGQLFQPASNLDYYSQSPSVDTFDEEPPLLEELGINFDHIWQKTLTVLNPMKPADGSIMNETDLTGPILFCVALGATLLMAGKAQFGYVYGMSAIGCLGIHALLNLMSNSGVSYGCVASVLGYCLLPMVLLSSCAVFFSLQGTIGTMSALLIITWCSLSASKIFISALAMEGQQLLVAYPCALLYGLFALLTVF
What are the official names of this protein?
Protein YIPF7, YIP1 family member 7.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane.
Protein: Y1462_KLEP3
Sequence: MSTPEKRPVSFFSLFNRGQHYAKTWPLDKRLAPVFIENRIIRATRYAIRIMPPIAIFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein KPK_1462.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CADH2_CRIGR
Sequence: TKPLDRELIARFHLRAHAVDINGNRVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVEVIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIHTDPNSNDGLVTVVKPIDFETNRMFV
What is the function of this protein?
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell.  Cadherins may thus contribute to the sorting of heterogeneous cell types.  Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence.  Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity).  Required for proper neurite branching.  Required for pre- and postsynaptic organization (By similarity).  CDH2 may be involved in neuronal recognition mechanism.  In hippocampal neurons, may regulate dendritic spine density.
What are the official names of this protein?
Cadherin-2, Neural cadherin, N-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Note=Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes.
Protein: METE_SALNS
Sequence: MTILTHTLGFPRVGLRRELKKAQESYWAGNSTREALLAVGRELRARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVSARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPVLLGPVTYLWLGKVKGEPFDRLTLLKDILPVYQHVLAELAKRGIEWVQIDEPALVLELPQAWLDAFKPAYDALAGQVKLLLTTYFEGVTPNLDTIIALPVQGLHVDLIHGKDDVAELHQRLPVDWLLSAGLINGRNVWRADLTEKYAQINALVGKRALWVASSCSLLHSPIDLSVETRLDTEVKSWFAFALQKCGELALLRDALNSGETAALEEWSAPIQARRHSRRVHNAAVEKRLAAITAQDSQRENPYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKGNLDANNYHTGIAEHIKQAIIEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVTRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLEWGVEAFRINAAVAKDETQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEAFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPAQRLWVNPDCGLKTRGWPETRAALANMVKAAHNLRQAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: SSRP_LACAC
Sequence: MKEKEENLIAQNKKARHDYFIKETLEAGIALTGTEIKSVRARRINLRDGYVQIINGSAYLENVHISEYKQGNRYNHDPLRSRRLLLHKKEINRLAKVQAERGIAIIPLKVYLKHGFAKVLIGVGQGKKEYDKRQTIKERDQKREIRRKYGI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RS5_PROMP
Sequence: MTDTPTKQENQSKTENPPSSNANEQRRGNRNNDRKRNRRGDSKNERDSEWQERVVQIRRVSKTVKGGKKMSFRAIVVVGNEKGQVGVGVGKAGDVIGAVRKGVSDGKKHLVRVPLTPNNSIPTLSKGRDGAANVLIRPAAPGTGVIAGGSIRTVLELAGIKNVLAKRLGSKTPLNNARAAMVALSQLRTHKSASRERGISLEQLYS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CHLL_PROMT
Sequence: MTSTITRKEDGEGSVQVKQDPKAQIQEGALVIAVYGKGGIGKSTTSSNLSAAFSKLGKKVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPEDFMFKGFNGVMCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVAAINAKAKNYKVRLGGVIANRSAELDQIEKFNERTGLKTMAHFRNVDAIRRSRLKKCTIFEMDSEEEGVVEVQNEYLSLAQKMIDNVEPLEAEPLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: TBP_CENSY
Sequence: MLDPRTRPRVVNVVSTSDLVQRVSAKKMAAMPCCMYDEAVYGGRCGYIKTPGMQGRVTVFISGKMISVGARSVRASFGQLHEARLHLVRNGAAGDCKIRPVVRNIVATVDAGRNVPIDRISSRMPGAVYDPGSFPGMILKGLDSCSFLVFASGKMVIAGAKSPDELRRSSFDLLTRLNNAGA
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: Y3959_DICDI
Sequence: MFKPDFKSRLLYFVLFVDIYGIFTNNIDKIVYKKVDCFKINIFIF
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0281023.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYN_ALKMQ
Sequence: MKTVSVKEIYRQTEQYAGQSIRVEGWIRTLRASKAFGFIELNDGTFFKNIQIVFDEDLHNFSDVSKFTISSAIIIEGTLEITPGAKQPFEIKATNVELEAHSHKDYPLQKKRHTFEYLRQIAHLRPRSNAFSAVFRVRSIAAFAIHQFFQEKGFVYTHTPIVTGSDAEGAGEMFRVSTLDFKNIPLDEEQQVDFKKDFFGKETSLTVSGQLAAEAYALAFKKVYTFGPTFRAENSNTARHASEFWMIEPEIAFADLQDNMELAEDMLKYMIRYVMEQAPEELEFFNQFVDKGLIDRLNHVANSEFGKVTYTEAVKMLQESGEEFEYPVEWGHDLQTEHERYLTEKVFKKPVFVMDYPKDIKAFYMRMNDDNKTVAAMDLLVPGIGEIIGGSQREERLDVLTDRMKQMGLDEEEYWWYLELRKYGGVKHAGYGLGFERAIMYLTGMANIRDVISYPRTPKSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCT_ECOUT
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: GG6L7_HUMAN
Sequence: MMSEKTQQRKLAGTKKKFTDYHQWNSAGVGTGATDTKKKKINHGANPETTTSGGCHSPEDKQQNRAQLKEENKASHQHQQALRRQLEAQDHTIRILMCQKTELETALHDSQDAARKFEEDSKDLAARLHHSWHFAGELQRALSAMSAEHERADKYIKELTKEREAMSLELFRNIITNKELKEKNAELQEKLRLVETEKSEIQLHIKELKRKLETDKIPLPQVQTNTLQEKMWRQEEELRDQEELRDQEKLRKHEEKMWRQEQRLRDQEKELREQEQQMQEQEEQMRKQEEQMRKQEEQMRKQEEQMRKQEEQMRKQEEQMRKQEEQMGKQEEQMGEQEEQMRKQEKQMLKQKEQMRKQEEQMWKQEEQIGEQEEQMRKQEEQMWKQEEQIGEQEEQMRKQEEQMWKQEEQMGEQMRKQEEQMGEQEEQIRKQEEQMGEQEEQMRKQEEQMGEQEEQMRKQEEQMGEQEEQMRKQEEQMGEQEEQMGEQEEQMRKQVERLQFKEERLWDEYEKMQEEEEKIRRQVEKRREKKERMGEQEKTQEERCSEPCLPPSKYPSDMSHPGSLEPAREAGKGYSHDNRTAQIMQLPPGMKNAQERPGLGSTSCIPFFYGGDKKKIKIISI
What are the official names of this protein?
Golgin subfamily A member 6-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the GOLGA6 family.
Protein: X_HBVC3
Sequence: MAARVCCQLDPARDVLCLRPVGAESRGRPVSGPFGTLPSPSSSAVPADHGAHLSLRGLFVCAFSSAGPCALRFTSARRMETTVNAHQVLPKVLHKRTLGLSAMSTTDLEAYFKDCLFKDWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.