PharMolix/UniProtQA huggingface dataset:
Protein: NUOC_MYCTU
Sequence: MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EIF3F_NEOFI
Sequence: MAETDSFLHLARPLGPVAVGSAPTTAPLNVVIQPQAIFSILDHSLRRNADQERVIGTLLGTRSEDGTEVEIRSTFAVGHTETTDQVEVDMEYQKQMLALHLKANPKEVLVGWYATSSELNTFSALIQNFYSGQGDGTWPHPAVHLTVSTEPGKDIETRAYISAPVGVTAERAADSAAFIPVPYEIRYGEAEKSGLETIASAKDAESRATNIFTDIEALERAIEEVLGMIDRVSRYVESVIDEEAPASTALGQFLLNALALAPKVEPADIERDFNNHIQDVLVVSYLANTIRTQMELSNRLATAQLTLGGEGASAEAGAQRGQRGGRGGRGGQQRTQERASEEVRA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_SHIF8
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINAGEISGPIVIKGRYIAGVGAEYADTPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVINGQNALLDKLDAFRYLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAASNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLALSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYRQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: SSPP_STAAM
Sequence: MKRNFPKLIALSLIFSLSVTPIANAESNSNIKAKDKKHVQVNVEDKSVPTDVRNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVLNTEGNIDYIVTISPKITKYSSSSSKYTINVSPFLSKVLNQYKDQQITILTNSKGYYVVTQNHKAKLVLKTPRLEDKKLKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQYINKLENFKIRETQGNNGWCAGYTMSALLNATYNTNKYHAEAVMRFLHPNLQGQRFQFTGLTPREMIYFGQTQGRSPQLLNRMTTYNEVDNLTKNNKGIAVLGSRVESRNGMHAGHAMAVVGNAKLDNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYRWYSSIYGY
What is the function of this protein?
Cysteine protease that plays an important role in the inhibition of host innate immune response.  Cleaves host elastins found in connective tissues, pulmonary surfactant protein A in the lungs, and the chemokine receptor CXCR2 on leukocytes.  Proteolytic cleavage of surfactant protein A impairs bacterial phagocytosis by neutrophils while CXCR2 degradation blocks neutrophil activation and chemotaxis.  Additionally, promotes vascular leakage by activating the plasma kallikerin/kinin system, resulting in hypotension.
What are the official names of this protein?
Staphopain A, Staphylococcal cysteine proteinase A, Staphylopain A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROA_SALAR
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGIDYTLSADRTRCDIIGNGGALRAPGDLELFLGNAGTAMRPLAAALCLGQNETVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIMNHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGDDYIRITPPAKLHHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPDE2_MYCTU
Sequence: MTPPEERQMLRETVASLVAKHAGPAAVRAAMASDRGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLGTTLAELALLAAAKPDAQALTELAQGSAIGALVLDPDYVVNGDIADIVVAATSGQLTRWTRFSAQPVATMDPTRRLARLQSEETEPLCPDPGIADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVVADACHAPTPTNAATARLAASEALSTAAAEGIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the dehydrogenation of 5OH-HIP-CoA to 5OH-HIPE-CoA (PubMed:32101684).  Can also use octanoyl-CoA and dihydroferuloyl-CoA, with lower efficiency.  Cannot use 3-oxo-4-pregnene-20-carboxyl-CoA (3-OPC-CoA) (PubMed:32101684).
What are the official names of this protein?
Acyl-CoA dehydrogenase IpdE2, 5OH-HIP-CoA dehydrogenase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RL15_BORA1
Sequence: MSDIQLNSLKPAEGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTPLGQHLYAEVRLSDLQRLDVEEIDVQALKAAGVVGQGVRYAKVIKSGELSRKVVLRGITATAGARAAVEAAGGSLA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: COG3_DROPS
Sequence: MDDVATAQSENENLRKIRNRLMQWESKTDPLAALSVQQEEHLDVFANLWRDSGPTLPVGTTPTTAEPSDEANTEGAPTKSTDDIELPAEGLQNTNDFLLWFVDVNAEIEQRGDAVYHKYLQQLEQRKAECSHMLGQISVAMDRLGALSDEYEFVSQKTSALNTASEQLIDEQEKLQDLSNEIQRRLHYFSQVELLNQRLQSPTLSVASEAFRECLNKIDECLNYIEENPKFKDAATYNVKYRQCLAKASGLVRNYVTSVINQATEATLHPKNSATDSSSALQAPDAAFALYYGKYQTAAAKVKRVVQLIETRLEHSNDYTQLMTDLQQHYLAQRASVMSPAVNLSIQNVKTAHKGDHCSLTRSACGFLVHVCQDEQRLFYQFFSTGAPHLTVYLEGLCTILYDTLRPFIIHINHLETLAEICSILRIEMLEEHVQQNPSALEAFATIAHQLLQDVQERLVFRAHLYLQSDIQNFNPSSGDLAYPEKLEMMESIALSLQEPTPLRRSDSRASVISSVSSVLETESVDNSYRIKQMNSPADLHGMWYPTVRRTLVCLSRLYRCVDRPIFQGLSQEALKLCIQSVSYAGGKIGAAKTPIDGELFEIKHLLILREQIAPFRVDFTVKETSLDFSKVKTAAFGLLQKRKQLFSMGSNNALLEFLLEGTPQIKEHLLDSRKEVDRQLKTVCEKYIRDAVNMLIGPLITFLDKTQSLLAQAASTTASTPESSSPKASYVLRQSPWASPQQISSIIQETQRMIKAKLAVLQRAMQLYLSNRDTEFIIFRPIRNNIIQSFVKLEQLLTTNGYSTDDMIITSCPSAEQVSILLSSASILAAEGVASFAAAAARKISTSSSIEGAAAGGRKLSTMSNKAELLRESKAEELEAVRSEAAPAPAESTPSENVVAELEVPTSAQASSE
What is the function of this protein?
Involved in ER-Golgi transport.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 3, COG complex subunit 3, Component of oligomeric Golgi complex 3.
What is the protein family that this protein belongs to?
Belongs to the COG3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AIS_ECOHS
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDITGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLNGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL28_SHESM
Sequence: MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEEEKRFVQLRVSTKGIRLIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TRUB_BRUME
Sequence: MARRGKKKGRPISGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEATKTVPYAMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVPPQFSAIKIDGERAYDLAREGETVEIPAREVEIDRLEIVGFPDADRTEFEVECSKGTYVRSLARDMGRDLGCYGHISDLRRVEVAPFTDEDMVTLAKLEAVWPPLPPKDEDGNVIEPAPRRDFSALDALVIDTGAALDCLPQVPLSDDQAQRVRLGNPVILRGRDAPLEADEACVTTRGKLLAIGYIEHGQFKPKRVFTAG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CYC6_SYNP3
Sequence: MKTLLTILALTLVTLTTWLSTPAFAADIADGAKVFSANCAACHMGGGNVVMANKTLKKEALEQFGMNSADAIMYQVQNGKNAMPAFGGRLSEAQIENVAAYVLDQSSKNWAG
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-552, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: RL7_ACIAC
Sequence: MAFDKDAFLTALDSMSVMELNDLVKAIEEKFGVSAAAMAAPAAGGGAAAGGAAAEEKTEFNVVLAEAGSNKVAVIKAVREITGLGLKEAKDLVDGAPKNVKEGIAKADAEAAVKKLVEAGAKAELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MDTC_ECO81
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDDTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGAVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDEPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQQIIDRLRKKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPC_BRUME
Sequence: MSTDILRKIEAYKREEIAAAKARLALDELKARTRDQSAPRGFLKALEAKRAAGQFALIAEIKKASPSKGLIRPDFDPPALAKAYEEGGAACLSVLTDTPSFQGAPEFLTAARQACSLPALRKDFLFDPYQVYEARSWGADCILIIMASVDDDLAKELEDTAFALGMDALIEVHDEAEMERALKLSSRLLGVNNRNLRSFEVNLAVSERLAKMAPSDRLLVGESGIFTHEDCLRLEKSGIGTFLIGESLMRQHDVAAATRALLTGAEKL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MIAB_NEOSM
Sequence: MLLYLADVVIFSHAKVYMEKIEKKNNSLKKFHIKTYGCQMNVYDSEMIEKIVSGLGFTLSERAEDADLIILNTCNIREKAAEKLYSELGQIRLLQKKKQERILIVVAGCVAQAEGEEIMRRAENVDVVVGPQSIHSLPELIAKVNRQSGKAIKMEFDPIEKFDYLAEETRKRRVPQSSAFLSIQEGCDKFCAFCVVPYTRGAEYSRSTEEVYREALSLTTKGVKEITLLGQNVNGYHGTLDSGNKVLNLGQLISRLGKIPSLKRIRYTTSHPVDMHKELYDAHANESKLMPFVHLPVQSGSDKILKQMNRKYTTADYLKIINEFQNARSDIAFSSDFIVGFPGESDDDFQQTLALIEQVNYAQCYSFKYSPRPGTPGATYPQISEETKNTRLQKLQQLLKEKQLEFNKKMIGKTVTVLFDKKHPDKISGRTEYMQQVFSDDSNLLDKIVTMRVEDASTFTLKCTAEDIIST
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STREM
Sequence: MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFKALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRNHHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWGAYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLK
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRS5_YEAS1
Sequence: MTVKICDCEGECCKDSCHCGSTCLPSCSGGEKCKCDHSTGSPQCKSCGEKCKCETTCTCEKSKCNCEKC
What is the function of this protein?
Critical role in copper (specific) homeostasis and detoxification.  May protect by directly chelating and sequestering copper ions (By similarity).
What are the official names of this protein?
Metallothionein-like protein CRS5.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 13 family.
Protein: RK5_PAUCH
Sequence: MSLKQRYRETIQGKLLTELSFSNIHEVPKVTKITVNRGLGEAAQNAKFLEASITELSNITGQKVLVTRAKKAIAGFKIRQGMPIGVAVTLRGDRMYSFLERLINLALPRIRDFRGVSPKSFDGRGNYTLGVKEQIIFPEISYDKIDAIRGMDITIVTNARNDEEGRALLREMGMPFRSN
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, organellar chromatophore.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: PLSX_TOLAT
Sequence: MSVLTVALDAMGGDFGPSETVPAAAQALSLLPKLNILLVGDQNQLVPLLQQHALSSHPRLHLVHASQSVSMAERPVIALRNKTDSSMRVMLELVSSGRAQACVSGGNTGALMVMAMRVLTMLPHLKRPALCSSLPNLHGRHTVMLDLGCNVNCTPEMLWQFACLGDLFAKHVHAVSSPKIALLNVGEEVIKGSKLVQETAKLLASDKQFNYIGFLEGDQLISGQADVIVCDGFTGNIALKTAEGIARFFYSQIKASNEADKVKNKSNTAAEIQTSLSVMHPDHYNGASLLGLNGIVIKSHGRADRRALSNAILHAVAEIEQQLPRRISERFIAEHTYER
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RLMN_YERPN
Sequence: MSEQLLTASTPIDAAPLSDNTVQTTAPATSKINLLDLNRQQMREFFAEMGEKPFRADQVMKWMYHYCYDDFEQMTDINKGLRAKLQRVAEIRAPEVAEEQRSVDGTIKWAIKVGDQQVETVYIPEADRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGSLKSTGTRPITNVVMMGMGEPLLNLNNVVPAMDIMMDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRDEIVPINRKYNIETFLAAVRRYLDKSKANGGRVTVEYVMLDHINDSTEQAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVIDRTKRTLKKKMAGEPIAIKTV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGR_THEVO
Sequence: METYDVLVIGGGPGGSTAARYAAKYGLRTLMIEKRPEIGSPVRCGEGLSKGILNEADIKPDKSFIANEVKGARIYGPSEKRPIILQSEKAGNEVGFVLERDKFDKHLAALAAKAGADVWVKSPALGVIKEDGKVAGAKIRHENNVVEVRAKMVIAADGFESEFGRWAGLKSVILARNDIISALQYRMINIDVDPDYTDFYLGSIAPGGYIWVFPKGEGMANVGIGSSINFIHNRLELKNYLDRFIENHPGLKKGQDIQLVTGGVSVSKVKMPITMPGLMLVGDAARLIDPITGGGIANAIVSGMYAAQVSKEAIESNDYSPQMMGKYEKLVKDRFERKHLRNWVAKEKLAQLSDETLDKLVDIVSEQVLTTISVEAILKAIAEKYPEVVKELEDLI
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: SSRP_BURTA
Sequence: MSIIDNRKAFFDYHIEERYEAGLVLEGWEVKALRAGRGQIKEGYVVVKNAEIFLIGTHISPLPEASTHIKPDPVRTRKLLLHRDEIKKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKLHDKRETEKKRDWEREKARIMRSAT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CCYL2_HUMAN
Sequence: MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGEGLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSCDLGTILSYQAKRDAHRSLGIFDEQLHPLTVRKEVLEEYFKYDPEHKLIFRFVRTLFKAMRLTAEFAIVSLIYIERLVSYADIDICPTNWKRIVLGAILLASKVWSDMAVWNEDYCKLFKNITVEEMNELERQFLKLINYNNSITNSVYSRFYFDLRTLAHNNGLYSPVYLLDRERAWKLEAFSRMEQDKVFYSAAKNGSLSADDLIHLQRAKAILF
What are the official names of this protein?
Cyclin-Y-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin Y subfamily.
Protein: KGUA_STRA3
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREEFEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFIFLTPPDLEELEERLVGRGTDSPEVIAQRIERAKEEIALMREYDYAVVNDQVSLAAERVKRVIEAEHYRVDRVIGRYTNMVKETDKKLS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y964_METJA
Sequence: MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINILIHATTLGTNMFLGQEHLNPPKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRRDRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVVISFLHSYKNPIHEKKAREIIKNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYVMQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTIINNSPLVTNEYEVGGEVHAGRLIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPISAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLKLRKDLAEKAISKLAEKIGESVEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSILIPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIKIVKQIDVRYKGQSYELTIPWTGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGLLTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDKLKPGAIFEGPAVVEEYDSTIVIPPDYTAFVDKYGCLRIER
What are the official names of this protein?
Uncharacterized protein MJ0964.
What is the protein family that this protein belongs to?
Belongs to the HyuA family.
Protein: RS12_STRT1
Sequence: MPTINQLVRKPRQSKVVKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQSRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.