PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_SOYBN
Sequence: MVREKIRVSTRTLQWKCVESRIDSKRLYYGRFILSPLMKGQADTIGIAMRRVLLGEIEGTCITRVKSEKIPHEYSTIIGIEESVHEILMNLKEIVLRSNLYGTRDASICFKGPGYVTAQDIILPPSVEIVDNTQHIANVTEPVNLCIELKIERNRGYRIKTLKNFQDGSYPIDATFMPVRNVNHSIHSYVNGNEKQEILFLEIWTNGSLTPKEALYEASRNLIDLFIPFLHAEEDNFNLENNQHKVTLPLFTFHDILAKEKLRKKKKEIALKSIFIDQLELPPRIYNCLKRSNIHTLLELLNNSQEDLLKIEHFRVEDVKYILDFLEIEKHFA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KLRF1_HUMAN
Sequence: MQDEERYMTLNVQSKKRSSAQTSQLTFKDYSVTLHWYKILLGISGTVNGILTLTLISLILLVSQGVLLKCQKGSCSNATQYEDTGDLKVNNGTRRNISNKDLCASRSADQTVLCQSEWLKYQGKCYWFSNEMKSWSDSYVYCLERKSHLLIIHDQLEMAFIQKNLRQLNYVWIGLNFTSLKMTWTWVDGSPIDSKIFFIKGPAKENSCAAIKESKIFSETCSSVFKWICQY
What is the function of this protein?
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily F member 1, Lectin-like receptor F1, Activating coreceptor NKp80, C-type lectin domain family 5 member C.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: TBG1_EUPOC
Sequence: MPREIITCQVGQCGNQIGMEFWKQLCMEHGINPEGILEDFAVNGEDRKDVFFYQADDEHYVPRAVLIDLEPRVINGIQKSAYSSLYNPENIYIAKHGGGAGNNWGRGYTDAEKVQDEILEMIDREADGSDSLEGFVLTHSIAGGTGSGFGSYLLERLNDHYPKKLIQTYSVFPIENDVVVQPYNCLLSIKRLTLNADCVVVLDNNALTSIAVDRLKILQPTFSQINSIVSTVMAASTTTLRYPGYMNNDMVGLIASLVPTPRCHFLMTGYTPLSLDQKFNSVRKTTVLDVMRRLLQTKNIMVTGAVKKGAYMSILNVIQGDVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSKKSPYIDSGHKVSGLMLANHTGIRSIFKVLYDQYRTFRKRDAYMNIFKQTKIFEDNLDEFDSSDEVVKSLIDEYAAAEKMDYINWGNDDDDMQFDPREPPKFSNIQ
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-1 chain, Gamma-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: APOM_RAT
Sequence: MFHQVWAALLYLYGLLFNSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQRFLLYNRSPHPPEECVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK
What is the function of this protein?
Probably involved in lipid transport.  Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity).
What are the official names of this protein?
Apolipoprotein M, Apo-M, ApoM, Protein Px.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
What are the subcellular locations of this protein?
Secreted. Note=Associated with HDL.
Protein: UBIE_PSET1
Sequence: MSETPQKTTHFGYKTVAENDKASMVADVFHSVAAKYDVMNDLMSFGVHRLWKRQTIASSGVRKGHHVLDLAGGTGDLTAKFSQLVGETGQVILGDINSSMLKVGREKLHNLGLVGNIDYVQMNAEALPFPDNSFDLITIAFGLRNVTDKDKALRSMYRILKPGGRLLVLEFSKPEHEILSKAYDFYSFNLLPTMGKLVANDSESYKYLAESIRMHPDQDTLKSMMSDAGFEQTTYQNLTGGIVALHRGFKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: NREB_STAAM
Sequence: MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQHMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIYTSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC.  NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity).
What are the official names of this protein?
Oxygen sensor histidine kinase NreB, Nitrogen regulation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATGT_PYRAE
Sequence: MSFEIIAKDLAGRVGKLYTKSGVIETPALFPVVDPRKQELPSAVIERYFGQIITNAYFVYRLTGGRAVDIKKVLSWNAVLMTDSGAYQILRYGSVEVDPDEILQFQARIGSDIGVILDLPFDYEEPYESALLKVEETIRRAKRASAMLDKLEDMLVVGPIQGGLYLDLLATSAREISKLGFHIFAVGSPTTLLEEYRFDLLLEVILHVKANILREAPLHLFGAGHPLVLPFAVALGVDLFDSASYILYARDDRIMLRDRTLRLEDVKTDYLPCSTKLCHKPVKELREMPHEERIQLIAEHNLAILREELLEIKQRIHEGTLWEYLEIKARAHPTLYRFLRSLGRYKRLIEEYDPETHPETHGLFFYQDTAESRPEPHRHWSRTANLYTPSKVAIVIRAGEKPYNKSWEYRYLKSLVGDRAHVLFYDPVFGLVPEEVAEIYPLSQNEAEGESEAARAFAYEWLNNYDVILLYRVDLPMLSKKVIPLRSLDDVLHYI
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: RL29_ACAM1
Sequence: MALSKMADLKNLSVDEIDAKVQELKKELFDLRFQKATKETIQPHRFKHIRHEIAQLLTLKQQQS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PUR7_CAMJR
Sequence: MTKKEMLYEGKGKKLFKTDDENLLISEFKDDLTAFNAEKRGNESGKGALNCRISTEIFHLLEKNGIKTHLVETISDTEQVVKKCKIVPIEVIVRNVATGSLTKRLGIKDGTVLPFALVEFCLKDDALGDPFINDEHCLILNLVQNEAQISEIKNMARKINSILTPFFDNKNLRLIDFKIELGLTKDNELVLADEISPDSCRFWDKFSNEKLDKDRFRQDLGNVKMAYEEVLKRILN
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: KDPB_ECOSE
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXL2_HUMAN
Sequence: MGRLLRAARLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLPTGLEPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQSRIPWDSTQVICKDWSNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEVLPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQNYSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSHGEELRFVENGCHDNPTLDVASDSQSEMQEKHPSLNGGGALNGPGSWGALMGGKRDPEDSDVFEEDTHL
What is the function of this protein?
Acts as a ligand for vascular selectins.  Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
What are the official names of this protein?
Podocalyxin-like protein 2, Endoglycan.
What is the protein family that this protein belongs to?
Belongs to the podocalyxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BTUD_PHOPR
Sequence: MILDAKNLAMPPRLLPVSFTIDAGEIVHFIGPNGSGKSTAISMLSGLFEGQGEITFMGQLLSDYDLPSLARMRCYLSQQDRPAFSVAVYHYLALSLSALNNPRVDHVQHALDEICQALNITDKLNRNIQTLSGGEWQRVRLAAACLQVWPAINPEATLLILDEPAAALDIGQEAAMYKLIRRMAEQGIAVVMANHDLNRTLREADKVLLLNNGSCVVKGSPSDVMTVEQLESTFATQVQRIEHEGRSCLIFND
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LSPA_STRPD
Sequence: MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMIHLDFMDFAIFNVADSYLTVGVILLVICLWKEEDYGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDS4_ARATH
Sequence: MATFAELVLSTSRCTCPCRSFTRKPLIRPPLSGLRLPGDTKPLFRSGLGRISVSRRFLTAVARAESDQLGDDDHSKGIDRIHNLQNVEDKQKKASQLKKRVIFGIGIGLPVGCVVLAGGWVFTVALASSVFIGSREYFELVRSRGIAKGMTPPPRYVSRVCSVICALMPILTLYFGNIDILVTSAAFVVAIALLVQRGSPRFAQLSSTMFGLFYCGYLPSFWVKLRCGLAAPALNTGIGRTWPILLGGQAHWTVGLVATLISFSGVIATDTFAFLGGKTFGRTPLTSISPKKTWEGTIVGLVGCIAITILLSKYLSWPQSLFSSVAFGFLNFFGSVFGDLTESMIKRDAGVKDSGSLIPGHGGILDRVDSYIFTGALAYSFIKTSLKLYGV
What is the function of this protein?
May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction.  Promotes the biosynthesis of plastidial phosphatidylglycerol (PG) which is required for structure and function of thylakoid membranes and, hence, for photoautotrophic growth.
What are the official names of this protein?
Phosphatidate cytidylyltransferase 4, chloroplastic, CDP-DAG synthase 4, CDP-DG synthase 4, CDP-diacylglycerol synthase 4, CDS4, CDP-diglyceride pyrophosphorylase 4, CDP-diglyceride synthase 4, CTP:phosphatidate cytidylyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: ACCA_HAEIE
Sequence: MNQEYLDFELPIAELEAKIEALRAASDDKVDLTDEIKRLQKKSNELTKKTFANLDAWQVSRMARHPNRPYTLDYIEYIFTEFEELAGDRAFADDKAIVGGLARLDGRPVMVIGHQKGRTVKDKVSRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGIGAEERGQAEAIARNLREMAQLTVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAEKASTAAEVMGLTASRLKELNLIDNIVQEPLGGAHRNYAKIAENLKLRLKEDLAELDGLSKEELLNRRYERLMSYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LKAM1_HUMAN
Sequence: MPPPAKEGGRKGPRERSGKSAPGTAQGEERAKGAPATEPPKPGWALTPQGLAAMLPAQRHRHLLFGDLLEDVGAAASTFPCGSVEPGYRMPDPRPWTQSLELPAERQNRLLGVLKAAEARGRVRALRLRYTRMRAEEIALLIQRQKSARAAIRLELFLPPQLKPARIPDPLDRQERRRVETILEENVDGTIFPR
What are the official names of this protein?
Protein LKAAEAR1, LKAAEAR motif-containing protein 1.
Protein: FABZ_STRPC
Sequence: MDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFFNGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUNB_DROAA
Sequence: WYSSMFAANIKQEPISHHHHHHHAHHSHHAHDSNSNASNSPHQSPLPSPNPPSHTNLQLEQYLKQQQQQQQQHQHQQQQQPMDTLCAAAMTPSFSNNDQNSRGWWSGLPNPMQTIMPANMRPSPTATAATTATDCCAPTTTAAAIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEPEKEHDLMSNSSEDMKYMA
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QMCA_ECOLI
Sequence: MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP
What is the function of this protein?
Identified as a multi-copy suppressor of an FtsH/HtpX protease double disruption mutant.  May play a role in the quality control of integral membrane proteins.
What are the official names of this protein?
Protein QmcA.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein.
Protein: RL15_NOCFA
Sequence: MTIKLHHLRPAPGAKTDKTRVGRGEGSKGKTAGRGTKGTKARKNVPAAFEGGQMPIHMRLPKLKGFTNKFRTEYQVVNVGRIAELFPQGGTVGKAELVAAGAVRKNQLVKVLGDGEIGVAVQVTADKVTGSAKEKITAAGGTVTELA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PHS_BURCH
Sequence: MIHKLTSEERKTRLEGLPHWTAVPGRDAIQRRLRFADFNEAFGFMTRVAIKAQEMNHHPEWFNVYNRVDITLSTHDADGLTERDIELARFIDGAAAHAQPGA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: VXRB_VIBCH
Sequence: MSNQWWDEWAEKCHSKAHRQLLFWRYLVKQTLLLVEDDKNLADGLLVSLEQAGYDCLHAETIADVKQHWDKADLVILDRQLPDGDSVQHLMDWKKIKDIPVILLTALVTVKDKVTGLDAGANDYLTKPFAEAELFARIRAQLRSPDSGQDDSKVVTSNLTIDKATREVFFNGESITLTRTEFDLLLFLASNLGRVFTRDELLDHVWGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKA
What is the function of this protein?
Member of the two-component regulatory system VxrB/VxrA involved in the regulation of diverses processes, including virulence, the type VI secretion system (T6SS) and biofilm formation (PubMed:26000450, PubMed:28607158).  VxrB positively regulates the expression of the T6SS, a virulence nanomachine that directly translocates effectors into bacterial or host cells, thereby facilitating colonization by competing with sister cells and intestinal microbiota (PubMed:26000450).  In addition, it activates vpsL expression and biofilm formation, and represses motility (PubMed:28607158).  May regulate biofilm formation via its regulation of key biofilm regulators and cyclic di-GMP levels (PubMed:28607158).  Significantly contributes to both attack and defense via T6SS, while also influencing competition via regulation of biofilm matrix production (PubMed:35880882).  Is critical for colonization in the infant mouse model (PubMed:26000450).
What are the official names of this protein?
Transcriptional regulatory protein VxrB, Vibrio type six secretion regulator B.
Protein: RL2_VEREI
Sequence: MAVIKMKPTSPGRRAVVKVTREHLHKGQPHAPLLEPQFQKAGRNNNGHITTRHKGGGHKHHYRVVDFKRNKDGIAAKVERIEYDPNRTAHIALVCYADGERRYIIAPRNLEVGATLLSGAEAPIRAGNTLPIRNIPVGSTIHCIELKPGAGAQIARSAGASATLLAREGTYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRQLGKAGVKRWMGIRPTVRGVAMNPVDHPHGGGEGRTGEGRHAVDPWGNLTKGYRTRNNKRTQSMIVSRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HEM1_BREBN
Sequence: MDILLLGLNYKTAPVEIREKFTFSDDGTARALHLLSQTKSIAECIILGTCNRTEIYVVCDQANIGRDYTRRFLAEWFGVEKEQFKDHLYIKENEQAIEHLFRVSSGLDSMVMGETQILGQVRDAFLLGQEHQTTGTVFNTLFKQAITFAKRAHTETAIGQNAVSVSYAAVELGKKIFGSFAGKSVLIVGAGKMSELTAKHLHANGSERVMVANRTLERAQLLAEKFKGDSCTMEQLPEALLTADIVISSTGATGYVLGKKELAPIMKQRKHRPLFMVDIAVPRDLNPDLHDLDNVFLYDIDDLEGIVASNVAERSREAERLDVMIQEEIVAFTTWYQTLGVAPLIAALRDKANTIQSEAMRKIENKLPNLSEREMHIIRKTTKGIVNQLLHDPVVRLKEMAATKDGEEVLDIFEKMFALEEILERKEQEAIWANDKNKQTSSSREQVLVSRFPD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: VKT3_NOTSC
Sequence: MSSGGLLLLLGLLTLWEILTPVSSKDRPHFCHLPHDTGPCNRNTQAFYYNPVYHTCLKFIYGGCQGNSNNFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor tigerin-3.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYA_SERP5
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPDNDPTLLFTNAGMNQFKDVFLGLDKRAYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAISYAWELLTGENWFNLPKERLWVTVYETDDEAFDIWQQQIGVPAERIIRIGDNKGGAFASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNLVFMQFNRQSDGTMLPLPKPSVDTGMGLERIAAVLQHVNSNYEIDLFSKLIAAVAKVTGATDLDNKSLRVIADHIRSCAFLVSDGVTPSNEGRGYVLRRIIRRAVRHGNMLGAKDTFFYKLVAPLIEVMGPAADELKRQQSLVEQVLKTEEDQFARTLERGLTLLDEELANLQGDTLDGETAFRLYDTYGFPVDLTADVCRERGLKVDEAGFEQAMEAQRRRARESSGFGADYNSMIRVDGASQFSGYDHEQQQSTVTALFRDGQPVNEIHAGEEAVVVLDETPFYGESGGQVGDKGVLKAANADFEVSDTQKYGQAIGHQGKLSHGSLKVNDRVDAKIDTVRRNRIRLNHSATHLLHAALRQTLGEHVAQKGSLVNDKYLRFDFSHFEAMKPEQIRTVEDLVNQQIRRNLPVQTEVMALDDAKGKGAMALFGEKYDDNVRVLTMGDFSTELCGGTHASRTGDIGLFRILSESGTAAGIRRIEAVTGDGAIATLHQQNDLLQDVAHLVKGDSNNLTDKVRAVLDRTRALEKELQQLKDQQAAQESASLSSKAKMVNGVQLLVSQLDNVEAKMLRTMVDDLKNQLGSAIIVLATTADDKVSLIAGVTKDLTDRVKAGELIGNVAQQVGGKGGGRPDMAQAGGTDVSALPAALDSVEAWVASKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y772_ARCFU
Sequence: MPVEGFITPDGVWTRGCLCMFADIDYTLNVFRGNPDEVVEQLRSAEKGRFNLLVYPLFYVDSRYSFLSSFLRLKMARNVEEASRIFKEAIYPINTLLRPFRDEKANAVSLNLFPLNFGIGKPKIAINGSNIGRSVILLTIDKNFGTKYDDFLPERGTDVEETKKILKKEFQFIEDVAISKGNLSIAKINNMSIREFLRSHNLRMRGDLENDVNREGIFGASPYILALISKETNGSTCLGLMDYNLKFYPSFFTLDIFYDEGLFLGEQLKGGLDRIKLVINSEKFDFIFVDQNIMLMFEDWIVNVFRGKDVYGVLVSFPSYTGKMQKRSMSEVEEKICLNTTLSTVFLNL
What are the official names of this protein?
Uncharacterized protein AF_0772.
Protein: AROC_SYNPW
Sequence: MGSSFGTLFRISTFGESHGGGVGVILEGCPPRLELDPLAIQAELDRRRPGQSKITTPRKEADQVEILSGVMDGLTLGTPIAMVVRNKDQRPQDYKEVEVAFRPSHADATYQAKYGIQARSGGGRASARETIGRVAAGAIARQMLQRSHGTDVVAWVKRIHDLEAQVDASTVTREAVDANIVRCPDAEMADRMIDRIEAIGQDGDSCGGVIECVVRRPPVGLGMPVFDKLEADLAKAVMSLPATKGFEIGSGFAGTLLRGSEHNDAFLPSDDGRLRTASNNSGGIQGGISNGEPIVIRVAFKPTATIRKEQQTINDRGEATTLAAKGRHDPCVLPRAVPMVEAMVNLVLADHLLRQQGQCSLW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PGM_NEIMB
Sequence: MASIARDIFKAYDIRGIVGKTLTDEAAYLIGKAIAAKAAEKGITRIALGRDGRLSGPELMEHIRRGFTDSGINVLNVGMVATPMLYFAAVNECGGSGVMITGSHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYLKHITGHIRLKRPMNIAIDAGNGVGGAFAGKLYKGLGNKVTELFCDVDGTFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDGDADRLGVVTKDGNIIYPDRQLMLFAQDVLNRNPGAKVIFDVKSTRLLAPWIKEHGGKAIMEKTGHSFIKSAMKETGAPVAGEMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIALPEGSNGHQVIDELAAKAEFEGATEIITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.