PharMolix/UniProtQA huggingface dataset:
Protein: PNP_XANC8
Sequence: MAKITKTFQYGKHTVTLETGEVARQASGAVIVKMDDTVLLVTAVAAKTAREGQDFFPLTVDYQEKFYAGGRIPGGFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIATVMSMNPDIDGDIAALIGASAALSLAGTPFNGPIGAAKVGYKNGEYILNPTITELKDSQLELVVAGTANAVLMVESEAALLSEEVMLGAVTFGHREMQKVINIINELTVEAGTKPSTWVAPAKNTALISALKEAVGTQLAGAFQVRDKLQRRDAISAIKKDVLESLAGRVASEGWSSAELSKEFGELEYHTMRDSVLETKVRIDGRALDTVRPISVQAGVLPRTHGSALFTRGETQAIVVTTLGTARDGQVIDAVAGEYKENFLFHYNFPPYSVGECGRFGAPKRREIGHGRLAKRGVLAVMPSLEEFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPVKAPVAGIAMGLVKEDDRFVVLSDILGDEDHLGDMDFKVAGTAEGVSALQMDIKIEGITEEIMKQALQQAKAGRLHILGEMSKALTTPRQELSDYAPRLLTIKIHPDKIREVIGKGGSTIQAITKETGTQIDIQDDGTIIIASVNAIAAQAAKSRIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSERVEKVGDKLKEGDLVRVKVLEVDKQGRIRLSIKAVEEGEGVPASAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM168_XENLA
Sequence: MCRSLRYCVSHCLYTAMTRLEEANREVNMYSSVRYLGYLAQLSLLVAICMGLYVRWDQTDDSFILVIFILGLVIFAIASILYYYFSMEAASLSLCNLWFGFLLGLLCFIDSSTFQHDLKEEATKYLLVSSIIIKTLSALVERICGCVRHRPTLLTSSEFLELVGFAIASTIMLMQKSLSIILLVAALAMIIIDLRMKSFLSIAILVVFASLTPELFFRSLDIPVNPYALSCFFFCIISNPFLDVYFSGLSVTERWKPYLYRGRFCRRFSVISIGLIELVFFVFAALKLGDLHLWYFVIPGFSIFGIFWLICHIIFLITLWGFNTKLNECHKVYSTHRPDNNSLDRVMASKGMRHFCLISERLVFFSLLATIILGAVSWQSSNGLFISIFLIVLPLESMAHGLFHELGNCLGGTSIGYAVVIPTNFCSPNGQPMLLPPEHVEELNLRSTGMLNSIQRFFASHMIETYGCDYSTSGLNFDTLHSKLKSFLDLRTSDGPRHDTYIIYYTGHSHSTGEWALAGGETLRFETLLEWWREKNGSFCSRLIIVLDTESSQPWVKEVRRVGDQYVAVQGAEMARVVDIEEADPPQLGDFTKEWVEYNCNPDNNINWTEKGRTVKAVYAVSKPWSDYTLHLPTGNDVTKHWMTYFPHITYPLVHLANWCGALNMFWLCKICYKCLKRLKMNWFLPAVLDTGQGFKLVKS
What is the function of this protein?
Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A.
What are the official names of this protein?
Transmembrane protein 168.
What is the protein family that this protein belongs to?
Belongs to the TMEM168 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABI_BACSU
Sequence: MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, Cold shock-induced protein 15, CSI15, NADH-dependent enoyl-ACP reductase, Vegetative protein 241, VEG241.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: DNLJ_BRUAB
Sequence: MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: 3SO93_BUNMU
Sequence: MKTLLLTLVVLTIACLDLGYTKTCFNDDLTNPKTTELCRHSVYFCFKNSWIAGGVERIERGCSLTCPDIKYNGKYIYCCTRDNCNA
What are the official names of this protein?
Neurotoxin-like protein pMD18-NTL3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group IX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EMC2_PONAB
Sequence: MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYGSKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 2, Tetratricopeptide repeat protein 35, TPR repeat protein 35.
What is the protein family that this protein belongs to?
Belongs to the EMC2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=May also localize to the nuclear envelope.
Protein: RS6_VIBA3
Sequence: MRHYEIVFMVHPDQSEQVAGMIERYTGSITEAGGTIHRLEDWGRRQMAYPINKLHKAHYVLMNVEAGQEVMDELETAFRFNDAVLRNMIMRTKGAVTEQSIMLKQKEERAERAPRRDDREERAPRREEEAKPEAAAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SYP_STRP2
Sequence: MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLPLANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKSDFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDAYSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSARTDLDRWVVLDKSVVSFDEIPVEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATNEYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVGNDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVRNAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFKLGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRYAWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKFSDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_MYCSK
Sequence: MTRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPDHEAALRTAYGLFDEAGAELGSVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAPLHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAATYAIDRDLSEQWHIRRYGFHGTSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTRSGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENAQLAYDVYIHRLRKYIGAYLALLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHLNESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRSA_YERPG
Sequence: MAQANLSEILFKPKFKHPETSTLVRRTHCNHVVNIHSALDGDTANHWYRMINRLMWTWRGIDPLEIEEVLSRIACSKAEHSNNELLDTVVGYRNGNWIYEWANQGMMWQQKAMEETDPGSAGQFWLNAANLYSIASYPHLKGDELSEQAEVLSNRAYEEAAKYLPYTLKELTFPISDGGSLSGFLHMPTVGSAPFPTVLMCGGLDTLQSDYHRLFRDYLEPKGIAMLTIDLPSVGASSRWKLTQDTSYLHQQVLQALADVPWVDHQRVSVFGFRFGANVAVRLGYLEPQRVRAVACLGPIVHHLLCNSDSLRKVPDMYMDVMASRLGMADSTDETLNTEMNRYSLKTQGLLGRRCQTPMLAGFWENDPFSPKEEAKLICSSSADGKLLAIPSKPLYENFHRALLQTSEWLEDKMR
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: STUA_DOTSN
Sequence: MNQPQPYMDQHAPAPPPASNMTQYSNYGAPQPLQPATHGYGAPTYPQYGQYGQSMPPMQAGHPVSAPMQGQMVNSLPLPTMSAPQQSGGTQQFQQSFDTTGQIAPHGMKPRVTATLWEDEGSLCFQVEANGVCVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKTRHVVKIGPMHLKGVWIPFDRALDFANKEKITELLYPLFVHNIGALLYHPTNQARQSIGNATMAARRPESSQEYMRTPQGTQAPALTHHHSMSNPINASMPPQPHSIAPHPASGRPQLDRAHTFPTPPASASSMPMTNGNMPNSYEYGSAGAVNSASTPPSNSQGMPQYQTSQPPYTQSYSTPGSYSQPQYTHQQPGVQRFGNIHSSPDGVKTEMGPPARAGAENDHPDHKVGGYGGQQDAEGEHEGEYTHTSASYGARRLSYNYKPNPAPGPLHQDSSHVSPEMTHSPHQNGSGRATPRTTNPYTGYNNTPQRQNQLPSSNLNYVMSSDARAGAPNGQEYAQQAYQPAPQYPAMNGIKRGREDDDQVDPYGRPSSALGEHKRQRTDPGAMSARPISQPHSIKAGGAVRR
What is the function of this protein?
Transcription factor that regulates asexual reproduction (By similarity).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).
What are the official names of this protein?
Cell pattern formation-associated protein stuA, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTXA_TOBAC
Sequence: MESNNVVLLDFWPSSFGMRLRIALALKGIKYEAKEENLSDKSPLLLEMNPVHKKIPILIHNSKAICESLNILEYIDEVWHDKCPLLPSDPYERSQARFWADYIDKKIYSTGRRVWSGKGEDQEEAKKEFIEILKTLEGELGNKTYFGGDNLGFVDVALVPFTSWFYSYETCANFSIEAECPKLVVWAKTCMESESVSKSLPHPHKIYGFVLELKHKLGLA
What are the official names of this protein?
Probable glutathione S-transferase parA, Auxin-regulated protein parA, STR246C protein.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: MURC_RICBR
Sequence: MLLLELKKTNQTLETIHFIGIGGVGMSGIAEILHNLGYKVQGSDLSENYNTKRLEAYGIKIFVGHTPQNITNVSYVVVSSAINRNNPEVKEALERKIPIIRRAEMLAELMRLKCSVAVSGSHGKTTTTSLVACLFEAAGLHPTVINGGIINNRSTNAYLGSSNYLIAEADESDATFISIPSTIAIITNIDPEHLDYYKDFDTLINAFRSFITNLPFYGFAVCCIDHKIVRELVNNITERKVITYGIDSDDAHITAFNISTDITSSTFDVKISLPNVSGVTIIEKITIPTPGRHNILNSLAAISVGVELDFGIKAIKNGFNSFKGVKRRFTKVAEYNQASVIDDYAHHPEEIKATLSTAKNIANKQHGKVIAIFQPHRYSRMQHLFDDFMRCFDDADLLYITDVYAAGESPIEGISGQSLIDNIIKLKYHNQANFLAKLDDSLEVIMNKASPGDMIIMMGAGNISNFANELPQKFGNLS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCN3_HUMAN
Sequence: MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
What is the function of this protein?
May function in innate immunity through activation of the lectin complement pathway.  Calcium-dependent and GlcNAc-binding lectin.  Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S. typhimurium and S. minnesota.
What are the official names of this protein?
Ficolin-3, Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Hakata antigen.
What is the protein family that this protein belongs to?
Belongs to the ficolin lectin family.
What are the subcellular locations of this protein?
Secreted. Note=Found in blood plasma, bronchus, alveolus and bile duct.
Protein: HEMH_PANTR
Sequence: MRSLGANMAAALRAAGVLLRDPLVSSSWRVYQPWRWKSVAAAAAATTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, mitochondrial, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PYHD_CPVOP
Sequence: MHGLDDAQYLQQKAHNKRISEFRSSSNSGINVTVVLKYTNGVVQVYNWQGTEVIAGSLNRQLMKFPNYMNPDKHGRIEWPGEGVEHQHGLIRSNGGNGSYDIGAGDPYAMQFIVQGSVDWNATRLRFFGPDGSRWMPDDQGGASVRAGLLNAAEDIINSKMQPLYFCDRMAGKSYYVRFDDKYAPRFPTIGFEVYRYRVGATNEMGGESARTAVASLISFPTFSTAYVNEKVAVENFFQPRELVYQNSYGYTV
What is the function of this protein?
Major component of the virus occlusion bodies, which are large proteinaceous structures (polyhedra), that protect the virus from the outside environment for extended periods until they are ingested by insect larvae.
What are the official names of this protein?
Polyhedrin, C-polyhedrin.
Protein: OCC1_RAT
Sequence: MGCGNSTATSAAAGRGKPGAVKDATEDSITEDDKRRNYGGVYVGLPSEAVNIASSQAKTVQKS
What are the official names of this protein?
Overexpressed in colon carcinoma 1 protein homolog, OCC-1.
What is the protein family that this protein belongs to?
Belongs to the OCC1 family.
Protein: MEND_HALLT
Sequence: MTAPNRNTLWARALIDELVAAGVDAVVASPGSRSTPLTVAAARTDDLRVFSQLDERSAAYFALGRARRTGKVTPLICTSGTAAANYHPAVMEASEARVPLLALTADRPPELRDSGANQTADQEKLYGDAVRFYKDLPEPAPNDRALRSLRTTVARAVGTAEGADPGPVHLNVPFKKPLEPTRVLDDVPADLDPVAERGRDGPYVDVTPGSPEPGDDALRRLGNELMTTDRGLIVAGPADPPGLDAEAVTALSHATGFPILADPLSGVRFGGHTRVAPVIGAYDAYLSAEVAGEAGDADASDSWNDPEVVLRLGASPTSKRLRKYLAETGADQYQVDPAGRWREAEFAATDLVVAEPSRLCARLSRLVAGGDGDADWRAQWEDADRVAQEIHGRERDGDIPADDEPVEFHEGDALRVVADALPDPATLFVSNSMPVRDLDRFVGPTTTSVTALGNRGVSGIDGIVSSALGAGSATTDDLTLVVGDLALYHDTNGLLALDRCDVDATVVLINNDGGGIFHELPIESFEPEFTESFKTPHGIEFEPMADLHGLAYTRIDARPDSVESAGNVADDLADAYTGARDADGSHLIEVRTDAESSHRTRKRLEAAVDRAVHGDEAE
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RBL_ANGEV
Sequence: MSPQTETKTGFGFKAGVKDYRLNYYTPEYDTKDTDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQAERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEVKGHYLNATAGTCEEMMKRAIFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHVHAGTVVGKLEGEREVTLGFVDSLRDDYIEKDRSRGIYFTQDWVSMPGVFPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVASEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFETIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BIN3_HUMAN
Sequence: MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSELRALSIVADD
What is the function of this protein?
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
What are the official names of this protein?
Bridging integrator 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MINC_XYLFT
Sequence: MSNVNMDFEQAGELKIGQVGIATLRIRTLNVPRLIQEMSDRVTRAPKLFRRTAVILDFGELPHPPDLATAKALVEGLRAANVLPVAIAYGTNEIDLLSQQLGLPLLSKFRAHYERQEVAAPPPQSTPPISTGRIQHTTVRSGQQLYAEHCDLTILNTVGAGAEVIADGNIHIYGTLRGRAMAGARGNAEMRIFCRDFQAELIAIAGRYKVLDDIPTELRGKAVQVWLEQNQIKIAALD
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: INSA_SHISO
Sequence: MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHLKNSGRSR
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 protein InsA.
What is the protein family that this protein belongs to?
Belongs to the IS1 elements InsA family.
Protein: NUOA_PHOLL
Sequence: MSMSTSTELFAHHWAFAVFLLGAFGLCALMLLGAFFLGGRAKARAKHVPYESGIDSVGSARLRMSAKFYLVAMFFVIFDVEALFLYAWSVSIKESGWLGFIEASIFILVLLAGLFYLVRIGALNWTPSRSSRQVSKPSVVININNSHPQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NSP1N_ROTB2
Sequence: MMSIQRATQINRQFDYMSIKELWMAKFPLHKPGDCLDMFKNGNYTGLTMECIQRTKASKKNTIFHIKSDFNSTDYDEPPISGFKMFTQHCCQRIDEHFCGALHPVISNIEFEQNQLRTRPQVASEFNLFIPCGIKNLKIESGEDPTWIVGTKFRKCMCLKPVMVAATIIGTPVNKNLITFCSSDYIQVIVNRNREGSCGICMGNTSTYEACGNWTNETWGEEFSLDLKLCYKCTPVAFIFSLMMSTGHKPYVSKRQFEENRRKWERVLNYKICEENLDSHLACANHENVYKSIKKYEFFDSIWVYHLANSSWVRDLTRECIESNPGPNYIQLLNEHSQRYGFIQPTYEIIAVVSDGHHSYQCTCYYKDTKTQSIGPSKKNAKHQAAEQMFRHQCF
What are the official names of this protein?
Non-structural protein 1, NSP1.
Protein: HUTI_BACCZ
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_CHLCV
Sequence: MPSVKVRVGEPVDRALRILKKKVDKEGILKAAKAHRFYDKPSVKKRAKSKAAAKYRSR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PXPA_SALA4
Sequence: MNIDLNADLGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCVREALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRHVKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVFADRGYQADGSLVPRTQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVIA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SIGH_MYCS2
Sequence: MTDVDRVEPETPPEREETDAELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTYINSYRKKQRQPSEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKAALQALPEEFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQLRDLLAGVARDRGFIRGPQLGEPEEVTS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released.  This sigma factor is involved in heat shock and oxidative stress responses.
What are the official names of this protein?
ECF RNA polymerase sigma factor SigH, ECF sigma factor SigH, Alternative RNA polymerase sigma factor SigH, RNA polymerase sigma-H factor, Sigma-H factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.