PharMolix/UniProtQA huggingface dataset:
Protein: RHSD_ECOLI
Sequence: MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMTSGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTKTPAPVGVFGPGWKAPSDIRLQLRDDGLILNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWGALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTSSLSSSDSSRPLSASAFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPAAPLVRYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYLYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTRSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYDEPGRLVSETSRSGETVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQYDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVILWYYDESDRITHRTVNGEPAEQWQYDGHGWLTDISHLSEGHRVAVHYGYDDKGRLTGECQTVENPETGELLWQHETKHAYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFGSMAGSNAAYELTSTYTPAGQLQSQHLNSLVYDRDYGWSDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKAHLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHVYQPYRLPGQQHDEESGLYYNRHRYYDPLQGRYITQDPMGLKGGWNLYQYPLNPLQQIDPMGLLQTWDDARSGACTGGVCGVLSRIIGPSKFDSTADAALDALKETQNRSLCNDMEYSGIVCKDTNGKYFASKAETDNLRKESYPLKRKCPTGTDRVAAYHTHGADSHGDYVDEFFSSSDKNLVRSKDNNLEAFYLATPDGRFEALNNKGEYIFIRNSVPGLSSVCIPYHD
What is the function of this protein?
Rhs elements have a nonessential function.  They may play an important role in the natural ecology of the cell.
What are the official names of this protein?
Protein RhsD.
What is the protein family that this protein belongs to?
Belongs to the RHS family.
Protein: OST48_HUMAN
Sequence: MGYFRCARAGSFGRRRKMEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (PubMed:22467853).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PRMA_BACCQ
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALERTVQPGNTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDIVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTG9_CYRSC
Sequence: MGTARFLSAVLLLSVLLMVTFPALLSAEYHDGRVDICSLPPDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hs1c, U15-TRTX-Hs1c, Kunitz-type serine protease inhibitor huwentoxin-11g9, HW11g9.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACYP_ECO57
Sequence: MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSVEVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: FA83H_MOUSE
Sequence: MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALTEGGPEAYNRFLASEGAPDFLCPEELEHVSRHLQPPQYVAREPPEGTPSDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHLKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAGALARMDAYALAPYSGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREELQRMPGGALEPHTGLRPLARPTEAGPFGELAGPRGFFQSRHLEMDAFKRHSYATPDGAGAVENFAAARQVSRQTFLSHGDDFRFQTSHFQRDQLYQQHYQWDPQFAPARPQGLFEKLRAGRPGFADPDDFALGAGHRFPELGADVHQRLEYVPSSASREVRHGSDPAFGPSPRGLEPSGASRPNLGQRFPCQATLRQGLDTASEAEPERRGGPEGRAGLRHWRLASYLSGCHGDGGEEGLPMEAEACEDEVLAPGGRDLLPSAFRTPAAFPAKGPKPGSGSGGGDSSEREGPEETSLAKQDSFRSRLNPLIQRSSRLRSSLIFASQAEGAVGTAAATTEKVQLMHKEQTVSETLGPSGEAVRSSASAKVAELLEKYKGPARDPGGAGGAVTSSSHSKAVVSQAWREEVVAPGGAGTERRSLESCLLDLRDSFAQQLHQEAERHPGAASLTAAQLLDTLGGTDRLPSRFLSAQGRSLSPQGRDSPPPEGLGTHQLPYSEPKGNPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTQAYPERKGSPTSGFPNRRGSPTTGLMEQKGSPTSTYPDRRGSPVPPVPERRGSPVPPVPERRGSLTFAGESSKTGPTEEVSSGPMEVLRKGSLRLRQLLSPKNERRGEDEGSFPTPQENGQPESPRRPSLSRGDSTEAAAEERGSRVRLASATANALYSSNLRDDTKAILEQISAHGQKHRGVPAPGPAHSSPDVGRPTTAGDLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPGSAEERDRLLRRMESMRKEKRVYSRFEVFCKKDEAGSSGAGDNLADEDTRDSKMGKFVPKILGTFKSKK
What is the function of this protein?
May play a major role in the structural organization and calcification of developing enamel.  May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments.  Thereby, it may regulate epithelial cell migration.
What are the official names of this protein?
Protein FAM83H.
What is the protein family that this protein belongs to?
Belongs to the FAM83 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with keratin filaments.
Protein: RL20_ACTPJ
Sequence: MARVKRGVIARARHKKVLKAAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSKFINGLKKASVEIDRKILADIAVFDKVAFAALVEKAKSAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PF21A_MOUSE
Sequence: MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRKNLIVKQEQPDKFQIQPLSQSENKLQTAQQQPLQPLQQQQPQQPQQQQQQQQQHAQQSAAAPPSLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHPEAEEKQAESRTVTPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFGALTPTSPPSSHPDSPENEKTETTFTFPAPVQPVSLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLEPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKELSSSISKCMEMKSSILARQKEMRSSLDKVKRLIRLVHGVDLCRPVDSEATAGALSNGPDCTPPANAASTPAPSPSSQSCTANCNQGEETK
What is the function of this protein?
Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells.  The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.  In the BHC complex, it may act as a scaffold.  Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation (By similarity).
What are the official names of this protein?
PHD finger protein 21A, BHC80a, BRAF35-HDAC complex protein BHC80, mBHC80.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_VEREI
Sequence: MGTFSIWHWLIVLLVVVVVFGTKKLRNIGTDLGSAVKGFKDGMKDAATDTAPAGQVANQSTADQTIDVQTKPKG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UPPP_XANOM
Sequence: MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWTLATGLGERDNRDYVLKVSVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHVAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASTIFIAMLLGLSRRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTEHWADVAVAFVAATITGFVVVKWLLSYIKKHRFTVFAVYRIVLGAALLLWLPAAAG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRC_ACIC5
Sequence: MDLQEKIRTLPTGPGVYLYKNADGEVIYVGKAKNLRSRVRSYLLEASQANAKTGSLMREAVDLDYITVGNEHEALALENNLIKQRKPRFNVLLRDDKTYPYVKLTLGDRYPKVFVTRRLRKDGAAYYGPFFPGNLAYRIVDLIHRSFLLPSCKVDLSRYHARACLQYYIKRCLGPCVKHLTTPEAYREAVRDAQWFLEGRGADLERSLEVRMQEAAAAEQFELAAKYRDLLVTLHQLQEKQRVASADDDDADVFGYHYENGMLAVNLFHMRGGKMVDRREFFWEELPEFMEEGAQEEEVLPAQAEGRGEVQVELRFEPGAFFSALLKQIYIEQPYVPRSIYVPVNFADREALAGLLAEQTHHRIELAVPQRGDKRSLVDLAGQNARQSYEQRFRVMQPNQKAIQEALQDALMLEELPRRIECFDISHIQGAETVASMVVWENGAMKKADYRKFQIKTVSGVDDFASMREVLTRRYRRVIEEKQAMPDVILIDGGIGQLRAAAAALEELGQTTQTVASIAKREEIIYLYGHEDEPIVLERRSPVLHLVQRIRDESHRFAIAYHRKRREMRDRDSELLEIPGVGTRTRTRLLEHFGSLRGVRKADVEALTAVVPRPTAEAIAAHFQGEKAEPEAAAGLVRIDESKTV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL333_STRA3
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVVFTEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ZN507_HUMAN
Sequence: MEESSSVAMLVPDIGEQEAILTAESIISPSLEIDEQRKTKPDPLIHVIQKLSKIVENEKSQKCLLIGKKRPRSSAATHSLETQELCEIPAKVIQSPAADTRRAEMSQTNFTPDTLAQNEGKAMSYQCSLCKFLSSSFSVLKDHIKQHGQQNEVILMCSECHITSRSQEELEAHVVNDHDNDANIHTQSKAQQCVSPSSSLCRKTTERNETIPDIPVSVDNLQTHTVQTASVAEMGRRKWYAYEQYGMYRCLFCSYTCGQQRMLKTHAWKHAGEVDCSYPIFENENEPLGLLDSSAAAAPGGVDAVVIAIGESELSIHNGPSVQVQICSSEQLSSSSPLEQSAERGVHLSQSVTLDPNEEEMLEVISDAEENLIPDSLLTSAQKIISSSPNKKGHVNVIVERLPSAEETLSQKRFLMNTEMEEGKDLSLTEAQIGREGMDDVYRADKCTVDIGGLIIGWSSSEKKDELMNKGLATDENAPPGRRRTNSESLRLHSLAAEALVTMPIRAAELTRANLGHYGDINLLDPDTSQRQVDSTLAAYSKMMSPLKNSSDGLTSLNQSNSTLVALPEGRQELSDGQVKTGISMSLLTVIEKLRERTDQNASDDDILKELQDNAQCQPNSDTSLSGNNVVEYIPNAERPYRCRLCHYTSGNKGYIKQHLRVHRQRQPYQCPICEHIADNSKDLESHMIHHCKTRIYQCKQCEESFHYKSQLRNHEREQHSLPDTLSIATSNEPRISSDTADGKCVQEGNKSSVQKQYRCDVCDYTSTTYVGVRNHRRIHNSDKPYRCSLCGYVCSHPPSLKSHMWKHASDQNYNYEQVNKAINDAISQSGRVLGKSPGKTQLKSSEESADPVTGSSENAVSSSELMSQTPSEVLGTNENEKLSPTSNTSYSLEKISSLAPPSMEYCVLLFCCCICGFESTSKENLLDHMKEHEGEIVNIILNKDHNTALNTN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 507.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURJ_ECOLI
Sequence: MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIPAFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPRINFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTVSLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLILTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVVAVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFARRTV
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Lipid II flippase MurJ, Peptidoglycan biosynthesis protein MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEFB1_SHEEP
Sequence: MRLHHLLLVLFFVVLSAGSGFTQGVRNRLSCHRNKGVCVPSRCPRHMRQIGTCRGPPVKCCRKK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Beta-defensin 1, BD-1, sBD1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: MAGB1_XENBO
Sequence: GKFLHSAGKFGKAFLGEVMIG
What is the function of this protein?
Has no antimicrobial activity against tested bacteria.
What are the official names of this protein?
Magainin-B1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_YERPA
Sequence: MQVLSSLRSAKNRHPDCKIVRRRGRVYVICKSNPRFKAVQGGTHKKR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ECPD_EIKCO
Sequence: MQAKISGFTLIELMIVIAIIGILAAIALPAYQSYTARAQVSEAISLMDGLKSSVADNYFNSMICADNQTVNHFGIAQRSRISGNYVESIHTRVATDPNYNCEMLATFKSTDAAAPIRGKTVLLSMKIVDGGTVWNCSSSDLANEFLPTACRH
What are the official names of this protein?
Fimbrial protein EcpD, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: MCE_SWPVK
Sequence: MEPLSIDKPFMYFDEINNELEYDPDSANEKHKKFPYQGQLKLLLCELFFLSKLQRHGILDGSTIVYIGS
What is the function of this protein?
Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities.  Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation.  At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap.  At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail.  In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase regulatory subunit, Poly(A) polymerase small subunit, PAP-S, VP39.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Poxvirus/kinetoplastid 2'-O-MTase family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: MTA_CHIHA
Sequence: MDPCDCSKSGTCNCGGSCTCTNCSCKSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RSMH_PHOLL
Sequence: MANSHFKHTSVLLDEAVNGLNIRENGIYIDGTFGRGGHSRLILSQLGTEGRLIAIDRDPQAIEVAKAITDPRFSIVHGPFSKLAHYTEKAGLIGKIDGVLLDLGVSSPQLDDPERGFSFMRDGPLDMRMDPTRGQSAAEWLMNATADDIAWVLKTFGEERFAKRIARAIVACNQEEPITRTKALADLIAQASPIKEKHKHPATKSFQAIRIYINSELEEIEQALEGALQVLAPQGRLSVISFHSLEDRIVKRFIRQNSRGPQVPAGLPLTEEQLKARGGRSLKSIGKMKPSEEEVADNPRARSSVLRFAEKVSE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M3K9_MOUSE
Sequence: MESSRSLLGCLASATAAPPGDDATGAGAEEEEDEEEAAAELGSHAALPYWTAVFEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRCQPGAEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWAGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEESGFFEMPKDSFHCLQDDWKHEIQEMFDQLRAKEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILERELNIIIHQLCQEKPRVKKRKGKFRKSRLKLKDGNRISLPSDFQHKFTVQASPTMDKRKSLISNRSSPPASPTIIPRLRAIQLTPGESSKTWGRSSVVPKEEGEEEEKRAPKKKGRTWGPGTLGQKELTSGDEGLKSLVDGYKQWSSSAPNLGKGPRSSPALPGFTSLMEIEDEDSEGPGSGENHQQHSPNQSYLCIPFPRGEDGDGPSSDGVHEEPTPVNSATSTPQLTPTNSLKRGGTHHRRCEVALLGCGAVLAATGLGFDLLEAGKCQLLPPEEPEPPAREEKKRREGLFQRASRPRRSTSPPSRKLFKKEEPMTLLGDPSASLTLLSLSSISECNSTRSLLRSDSDEIVVYEMPVSPVEAPPLTQCTHNPLVNVRVERFKRDPNQSLTPTHVTLTAPTQPSGHRRTPSDGALKPTAAPAVLGSRSPSSNGMSPSPGTGMLKTPSPSRDPGEFPRLPDPNVVFPPTPRRWNTQRDSTLERPKTLEFLPRPRPSANRQRLDPWWFVSPSHARSASPANSSSTETPSNLDSCFASSSSTVEERPGLPALLPLQAGPLLPAERTLLDLDAEGQSQDSTVPLCRAELNAHGPSPYEIQQEFWS
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Plays an important role in the cascades of cellular responses evoked by changes in the environment.  Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs.  The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors.  Also plays a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: RN2A_RANBO
Sequence: GILSTFKGLAKGVAKDLAGNLLDKFKCKITGC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  Weak hemolytic activity.
What are the official names of this protein?
Ranatuerin-2BYa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: NCAP_BCHK5
Sequence: MATPAPPRAVVFANDNETPTNSQRSGRPRTKPRPAPNTTVSWFTGLTQHGKQPLAFPPGQGVPLNANSTPAQNAGYWRRQDRKINTGNGTKPLAPRWYFYYTGTGPEANLPFRSVKDGIIWVHENGATDAPSVFGTRNPANDPAIVTQFAPGTTLPKNFHIEGTGGNSQSSSRASSRSSSRSSSRNGRSNNSSRNASPAPHGVGDVVGAGTLSVLLDLQKRLADLEAGKGNKQPKVITKKDAQAAKQKMRHKRVATKGYNVVQAFGMRGPGPLQSNFGDMQYNKLGTEDPRWPQIAELAPSASAFMSTSQFKVTHQSNDENGEPVYFLSYSGAIKLDPKNPNYNKWMEILDANIDAYKSFPKKERKQKPSGDDAATAPATSQMEDVPELPPKQQRKKRVVQGSIPQRSAGVPSFEDVVDAIFPDSEA
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: ACPS_CLOPE
Sequence: MIIGIGVDIIEIERVRQAIQNNKNFLSKLFTERELDYFISRNMNSEVIAGNFAAKEAVSKALGTGIRGFSFKDIEILRNELGKPEVILHNGANLIGNKLVGNNNSLRVHLSISHNNSSAIAYSVLEGEYYGNM
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3BP2_MOUSE
Sequence: MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEDRQPSPEPVQENANSAYYDAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKHLEELEEKSATPPPAEPASLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVDAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMTQKLGSGRGTGQMEGRFTGQRR
What is the function of this protein?
Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
What are the official names of this protein?
Ras GTPase-activating protein-binding protein 2, G3BP-2, GAP SH3 domain-binding protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, Stress granule.
Protein: YCAR_ECOLU
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.