PharMolix/UniProtQA huggingface dataset:
Protein: YOSE_SCHPO
Sequence: MKIERYFKAIARAFIITFLFSLILQDNGVLARKAKKQDKGAALKSIYDYHVRPYGTVVQSQIAKASPIVDAAKQATVNVKSYYDEHAKPKVENIRYEVNEVIDKKVAPCIKAFNEKARKIGSKVLDGDNLRELYTTGKERIHFFIVDVLIPFFQRVVQEVRTISRDIAEKLQYFWEIHAIPAYHHYKPIIQRGAMDGYMQLRYVFFPAAKATITQMIETSIRFLRTFLDMHIKPQLQHIYESVVEEKSEAFASATSSKILSEMSASMASSSAHYTSSPTILSRTKSVETPVPMEAAEEEPATEYSIPSSVTFNSQNDCFSNAMNYLEHEYETLVSTFTLSVSEHWEDLLRKATDSCQKELEAFEEISNLRVLAVENSLGNLIQKAEESNYDQAIMDLFEYVKDSILRVHERAIKLRTLSDSIRADVAENIEMGINSIREQAAASSEVALAACSGIKHNAEQVNKLNALIQKVYSYITAESEKVGNRYGETLDNVIKQHLSRIGSVASSAVQRLTAVKNSHKLKMVDRSSAELPNFDYLVSDQVHKIVEINDEHADCDDVNFSTASFEIYERSIPTHGADSERKILKRDSLLNEDDEIFNDLNSDKTIKTNQATSTSSSNTQEISYTGTLNDNINEGLSTFPSIDIPASEADNVYSILPIDVSTSEAEGAYSILPIDVPKSVAEETYSFLPSDVPKSEAEKVYSILPIDVPQSVAEETYSFKPSDIPESEAEKIYSILPIDVKDPSLEKDGHVIDSSNLQTDSVKDYSEVSRADNLDASSDTIFSVLHAENEASITKEVHSTPLSDVASSEAEKVYTILPIEVPTDPLPNYSSDVESELTSD
What are the official names of this protein?
Uncharacterized protein C21C3.14c.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMN6_ECO8A
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDE12_CAEEL
Sequence: MSSFGNNAGGGGREYHDDRSNRDHRHGNGGSDAGQRRREDHNSSYQSYRRPDGRQDSYGGGHQGNHGNSYGRREDDRSHSRDNHGGSRYGERDDRGNNGRSADNRYSQSNYNYDSNRGGQHYQRDNHGSKDDRGPMNQYNDHGSNHNSNSRNDQYRQGSYQGDGHSGYRRDDDRRRNDNDQARPYQSNRDSDRNSPRDHHNYNSQSSPRSHQGGQDRYSAPKEDNQRRYDNHQGGHDSYRGQNSGGYSGNNSGEYRNDYRSQQDSRDHRSGGNNSSSGFKNDGGFGGNDNRGFGNNGGGSFGNPNNSYRGNSNNIGGFHRSDGSNSEGVNAPVRAPRDWVPVTRDIDELVRETADRLADCDVGQDRAVEIRNAEKDVRLTSWTNSGLHPTILETLKRIKYNNVRTIQGAMIPQVLDGHDVLGQAETSAGKTAAFGLPIIDKILRMDEETRNKARQDDGPLALILAPTRELAAQIHEALRTYCQNTDIIVLLSYGQSDRARSLNEIRNGCDILIGTCGRIMDFTVKSHISLLHLRFLVFDEADRLLQDMKKDPLGHLGAIIKDAGFMESAATRQTIMTSATFNASVMTVANELMKRLPGQDEMIKIVLANGRLSKRVNLEFFECKGLAEKNAKLREILKQNVNGKTLKTIIFVQKKDQCDACAAKLTSGGMLAQTLHGDRSQDMREKLINDFKSNRVNLLVTTDLLSRGIDVSDLDRVINFDLPDGDPDQGADTFIHRAGRTGRTGRKENGLCVSFVDPQSDRDSLLAPKLVELIISQNLPDLKVPDFLDAMAKSSRGKSGTSGFGQRGGYGGRGGGFGGTGRGRGGGVFGGGGRGGDFGGSGNFGGSGGGGSFGGSGGGGGFGGVKPSGFGGSRNNAEPTSSGGGFGAPKAPTGFPSDNNDASEDAPAAGGFGFSTKAAQDAKKAEESATLGSSTFGTANNADEEPTETGADGNDDDEW
What is the function of this protein?
Probable ATP-dependent RNA helicase involved in RNAi-mediated gene silencing (PubMed:24684930, PubMed:24684931).  Specifically required in the endogenous siRNA pathway for biogenesis of secondary endogenous small interfering RNA (siRNA) intermediates called 22G-RNAs (PubMed:24684930, PubMed:24684931).  May associate with and recruit rde-10 to primary siRNA-targeted mRNA for secondary siRNA synthesis (PubMed:24684930).  May be recruited to target mRNAs by rde-1 and/or ergo-1 (PubMed:24684930, PubMed:24684931).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase rde-12, RNA interference defective protein 12.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasmic granule. Cytoplasm. Cytoplasm, P-body. Note=Colocalizes with pgl-1 in perinuclear P granules. Colocalizes with rsd-6 in a subset of germline and embryonic foci.
Protein: MAEA_MACFA
Sequence: MAVQESAVQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex.  MAEA is required for normal cell proliferation.  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity).  Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity).  Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (By similarity).  Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis.  Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).  May contribute to nuclear architecture and cells division events (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein transferase MAEA, Macrophage erythroblast attacher.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Detected in a nuclear, speckled- like pattern (By similarity). Localized with condensed chromatin at prophase; Detected in nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis (By similarity). Present in cytoplasm, nuclear matrix and at the cell surface in macrophages; predominantly nuclear in immature macrophages and predominantly detected at the cell surface in mature macrophages. Colocalizes with F-actin in macrophages (By similarity).
Protein: RBL_OENBI
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKEIKFEFQAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYC1_PHOPR
Sequence: MLKIYNSLTKQKEEFKPIQPGKIGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYSGYDLTFVRNITDIDDKIIKRAAENGESCESLTERLIGEMHKDFDALGMKRPDIEPRATEFIAEIIILCERLIERGFAYVASNGDVMFEVSKFEEYGRLSRQDLDQLQAGARVDIDMAKRSPLDFVLWKMSKPGEPTWESPWGAGRPGWHIECSAMNSAILGDHFDIHGGGSDLQFPHHENEIAQSCCATGSQYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDAESVRYFLMSGHYRSQLNYSEDNLKQARSALERLYTSLRGLDLTAQAEGGEEFVTRFTASMNDDFNTPEAYSVLFDMAREINRLKADETIANNIVQASALGARLRELADILGLLSQDPEAFLQGGAGQDDVAEIETLVQQRLDARAAKDWAAADAARDKLLAMKIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase 1, Cysteinyl-tRNA synthetase 1, CysRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_BOTFB
Sequence: MSIDLNWETLTTGPDGIALAERIRDFVHAKFQTVTLPRFIKGVKVHTFEFGSIAPEVELKDICDPLPDFYEDIDDDYVEDDEDEENSENSQTDEENEVAKTLRERRRLDRVERTANGSSHVSTPPAYIDTRYPGLRSMQASGDTGSPFLGVSTPGIPGGTSNLSYFHSQLASGLSGTQTPLAAVAGAHLPQGWPDRPSPSLHLSALRNQSHTPLSHTASERSMTPPQIADLNQQSLREKASVSTLAASSSTTRPATRDGVPEATIPEEHAGESEESTSPPRRFREPKVEDLQTVFRVRYSGNIRLSLTVDILLDYPMPSFVGIPVKLNITGLSFDGVAVLAYIRKRAHFCFLSPEDAYAAIGADEKDADASAGMKMGALLHEIKVESEIGQRENGKQVLKNVGKVEKFVLEQVRRIFEDEFVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ILVD_CHLAD
Sequence: MSDNRRSRMITEGPQRSPNRAMLRAVGFGDNDFTKPIVGVANGHSTLTPCNAGLGALAARAEAAIRAAGGMPQIFGTITVSDGISMGTEGMKYSLVSREVIADSIETVVNAQRMDGILAVGGCDKNMPGALIAMARLDIPAIFVYGGTIKPGHYKGRDLTIVSVFEAVGEYSAGRIDEHELLEIERHACPGVGSCGGMYTANTMSSAIEALGLSLPGSSTMAAEDEEKAISAARSGEVLVEAIRANRTARQMLTRKSFENAIAVVMALGGSTNAVLHLLAIAYAANVPLTIDDFETIRQRVPVLCDLKPSGRYVATDLHRVGGVPQVMKMLLNAGLLHGDCMTITGQTIAEVLADVPDEPPADQDVIRPFHKPLYPQGHLAILRGNLAEEGCVAKITGIKQRSITGPARVFDAEEECLEAILSGKIKPGDVVVIRYEGPKGGPGMREMLAPTSAIIGAGLGDSVGLITDGRFSGGTYGLVVGHVAPEAAVGGTIALVEEGDSITIDADARLLQLNVSDEELARRRAAWQPRPPRYTRGVLAKYARLVSSASLGAVTDRFDGESA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: IXTPA_LISIN
Sequence: MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASLLNQTVIADDSGLIVDVLNGAPGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFHCTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFFLPEFGLTMAEIPAEKKNEISHRANAIKQLEKDLAEVVEKVTKK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ACP_SHEDO
Sequence: MSNIEERVKKIIIEQLGVKEEDVKSAASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYVSKNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC76_ARATH
Sequence: MESVDQSCSVPPGFRFHPTDEELVGYYLRKKVASQKIDLDVIRDIDLYRIEPWDLQESCRIGYEERNEWYFFSHKDKKYPTGTRTNRATMAGFWKATGRDKAVYDKSKLIGMRKTLVFYKGRAPNGQKTDWIMHEYRLESDENAPPQEEGWVVCRAFKKKPMTGQAKNTETWSSSYFYDELPSGVRSVTEPLNYVSKQKQNVFAQDLMFKQELEGSDIGLNFIHCDQFIQLPQLESPSLPLTKRPVSLTSITSLEKNKNIYKRHLIEEDVSFNALISSGNKDKKKKKTSVMTTDWRALDKFVASQLMSQEDGVSGFGGHHEEDNNKIGHYNNEESNNKGSVETASSTLLSDREEENRFISGLLCSNLDYDLYRDLHV
What is the function of this protein?
Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity).  Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE).  Triggers thickening of secondary walls (PubMed:25148240).
What are the official names of this protein?
NAC domain-containing protein 76, ANAC076, Protein VASCULAR RELATED NAC-DOMAIN 2.
What is the protein family that this protein belongs to?
Belongs to the plant vascular related NAC-domain protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: JAGN1_RAT
Sequence: MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLLSHDQVAMPYQWEYPYLLSIVPSVLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSVMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKRK
What is the function of this protein?
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function.  Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport.  Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
What are the official names of this protein?
Protein jagunal homolog 1.
What is the protein family that this protein belongs to?
Belongs to the jagunal family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEPA_CALS4
Sequence: MSERMKYIRNFCIIAHIDHGKSTLADRLIEKTGFLSEREMDKQILDNLELERERGITIKLKPVRMIYKAKDGNEYELNLIDTPGHVDFTYEVSRSIAACEGALLVVDASQGIEAQTLANVYLALEHDLEIIPVINKIDLPSADPERVKREIEDIIGIDASEALLTSAKEGIGIEEVLEAIVKRIPPPQGDEDKPLKALIFDSFYDNYKGAISFVRIVDGKVKRGMRIKMFSTGKVFEVTEVGSFRPDLYPVEELKAGEVGYIAANIKNVKDTRVGDTITDADNPADSPLPGYKEVVPMVFCGIYPADGEDYENLKEALEKLQLNDASLVFEPDTSAALGFGFRCGFLGLLHMEIVQERLEREYNLNLVTTAPSVIYKVYKTNGEVLELDNPTKMPPPTQIDHIEEPIVEATIMVPTDYVGPVMELCQERRGVYLGMEYIEKTRVLLKYEMPLNEIIYDFFDALKSRTRGYASLDYEFKGYKKSDLVKLDILVNGEVVDALSMIVHKDKAYEKGRKIVEKLKENIPRHLFEIPIQAAIGSRIIARETVKALRKNVLAKCYGGDVTRKKKLLEKQKEGKKRMRQIGTVEIPQEAFMSILKLDDQK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPB1_CANAL
Sequence: MGKQQKKHSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASQLCPINSLIIGVDIVPIKPLPNVITFQSDITTEDCRSRLRGHMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLTAGGTFVTKIFRSRDYNNLMWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKKLDPRLLDPKEVFEELGGGNESKQNNEAKIFNPEKFSSQRQRQGYQEGDYTLFHTMPIMDFIKQDDPINQLGSLNKFDLPAPKDDDNDDDDHDHEWKILSKLKLCTPELLECIKDLKVLGRKEFKMILKFRKQARDILGIDKDEKEEEEENPKIEVEPLTEEQKIDQELQDLINKQKQKAKRLKKNANELKQKEIIRNQMNMLTDMNIGIEAAQIGADSLFNLKTAEKTGQLDKLAKGKKKMIFNDEELAKDNEIHIDEEEINDNDKDSADELDELENQLDDMYHQYQARKAERDANYRAKQARGDADDEAWNGIEEDNDDVESGKDYEMESESDDDDDEHIRLIAEKKSNGSLSRTARNFFASDSIFNELSDDVILEEIENKTKGSNGKMVESIQEQVANDNNENDDGDNDEEESDFEIVPNQKSDDDDDDESMNSDDDEVSTTTKSTTHQQKVDLATVEAMTLAHQVALGQKNKYDLIDEGINRYSFRDKDNLPDWFIDDEKKHSKLIKPITKEAAIAIKEKQKQLNARPIKKVLEAQSRKKLRALKRLEKIKKKSDLINEDSGKSERDKADEISKLMKKLNKKQKQKPKTTVVVARGSNRGLSGRPKGVKGKYKMVDGVMKNEQRALKRIAKKYKK
What is the function of this protein?
Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
AdoMet-dependent rRNA methyltransferase SPB1, 2'-O-ribose RNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ADCC_STRR6
Sequence: MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTTLIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYPRKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFILDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSPWRCFNVHENGQEVGHA
What is the function of this protein?
Part of the ATP-driven transport system AdcABC for zinc.  Required for transformability (By similarity).
What are the official names of this protein?
Zinc transport system ATP-binding protein AdcC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: MIC60_ASPNC
Sequence: MVVRPMMLRSSVAPGRQLLLSSARQRTASQWLSRAGASSRLSGQRFFADIKPPTTAAPTPATPSSESAVPPETVPKPSPAGQESTLPPSTPPTPAPKGGRFRRFLLYLLLTSGFAYGGGVFLALKFDNFHDFFTEYIPYGEESVLYFEERDFYRRFPNTLRNQNRLNPTPRDEGNKITIPSKSGLTSKVAEEEISGADVSQKGPHMSATPAQKSSEAQTKPAAAKPEDKTTAVVKAKEDKAAKEAEKKEEPRQPAIPAVTPLEFAQVNEGDEAIVQELVKTFNDMITVISADENSGKYSQPVAKAKEELQKVGEKIIAVREEARRAAQEEIQQAHATFDESARELIRRFDEMRAADAAQYREEFEAEREKLAHAYQEKIRTELQRAQEVAEQRLKNELVEQAIELNRKYLHEVKELVEREREGRLSKLNELTANVSELEKLTSGWREVIDSNLRTQQLQVAVDAVRSVVDRSAVPRPFVRELVAVKELAAEDPVVEAAISSINPAAYQRGIPSTSQIIERFRRVADEVRKASLLPEDAGIASHAASVVLSKVMFKKDAVAGSDDVESVLYRTESLLEEGNLDAAAREMNSLSGWAKILSKDWLVDVRRVLEVKQALEVIETEARLQCLRVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit mic60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLN1A_BACSU
Sequence: MAKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism (PubMed:25691471).  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (PubMed:24158439).  Feedback-inhibited GlnA interacts with and regulates the activity of the transcriptional regulator TnrA (PubMed:11719184, PubMed:12139611).  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation (PubMed:11719184, PubMed:12139611, PubMed:25691471).  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity (PubMed:11719184, PubMed:12139611, PubMed:25691471).  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes (PubMed:25691471).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_ALNGL
Sequence: MAEITHIKARQIFDSRGNPTVEAEVTTANGVVSRAAVPSGASTGVYEALELRDGGSDYLGKGVLKAVDNVNKIIGPALIGKDATEQTAIDIDFMFQQLDGTVNEWGWCKQKLGANAILAVSLAVCKAGASVKKIPLYKHIANLAGNPKLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMKMGVEVYHHLKAVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYVVIGMDVAASEFYEKDKDITNFKEENNDGSQKISADQLKDLYKSFVDEYPIVSIEDPFDQDDWEHYSKLTAEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTESIEAVKMSKRAGWGVMAHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLRIEEELGSEAVYAGANFRTPVEPY
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_YERPE
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: ELYA_ALKAL
Sequence: MKKPLGKIVASTALLISVAFSSSIASAAEEAKEKYLIGFNEQEAVSEFVEQVEANDEVAILSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPAISYIEEDAEVTTMAQSVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPNAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSISYPARYANAMAVGATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSLGSTNLYGSGLVNAEAATR
What are the official names of this protein?
Alkaline protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.