PharMolix/UniProtQA huggingface dataset:
Protein: FAHD2_ORYSJ
Sequence: MAAAAQRLLAASTKIVGVGRNFVAHAKELGNPVPKEPVLFLKPTSSFLHAGVAGAAIEVPEPVESLHHEVELAVVISQRARDVPEASAMDFVGGYALALDMTARELQSAAKSAGLPWTLGKAQDTFTPISAVIPKSDVANPDDLELWLKVDDELRQKGSTSDMIFKIPSLISYISSIMTLMEGDVILTGTPEGVGPVRPGQKIKAGITGLIDVEFDVQKRKRSFST
What is the function of this protein?
Probable acylpyruvase.
What are the official names of this protein?
Probable acylpyruvase FAHD2, mitochondrial, Fumarylacetoacetate hydrolase domain-containing protein 2, FAH domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNMA_CAMJE
Sequence: MKILVAMSGGVDSTVTAYKLKNLGHEVIGCYMKLHGKPNYHEENIKKVEKVANFLQIPYHILDLQEDFKNKVYMPFVDTYKEGKTPNPCALCNRFIKLGKLLEFAKSLGCEKLATGHYARLENNLIKTAVDESKDQSYFLASADKEALKYLIFPLGEMKKEDVKKFASTIEVLKSFATQKESSEICFVEDTYVQVLDQFMDTKIPGEVLDSSGKVVGKHEGYMHYTIGKRRGFEVRGAHEPHFVLKINPKQNQIIVGTKEELKISEFNLKNINLFIDAKELDCEVKIRYRSKSTPCKVEIYEDKSAKIILKDPVYGLASGQMAVFYDHDKVIASGFIE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_CAMC5
Sequence: MKNILQGAMTALITPFKNGKLDEETFEKLIKRQIKNGIDVVVPVGTTGESATLTHNEHKICIEIAVNACKDTNVKVLAGAGSNATHEAIDFAKFAQSHGADGILSVAPYYNKPTQEGLYQHYKAIAESIDIPVLLYNVPGRVGVDILPSTVFRLFKECKNIFGIKEATGSIDRCVDLLAHEPNLVVISGEDAINYPILSNGGKGVISVTANLLPDYICELTHLALDEEYTKAKAINDKLYNINKILFCESNPIPIKAAMYIAGLIGNLEYRLPLCEPSSENFKKIEQTMKNYEIKGF
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_LISIN
Sequence: MVKEITDATFEQETSEGLVLTDFWATWCGPCRMVAPVLEEIQEERGEALKIVKMDVDENPETPGSFGVMSIPTLLIKKDGEVVETIIGYRPKEELDEVINKYV
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: OLEE1_BETPN
Sequence: MAKSIIIQAPALCFLSLLGFAYSESRFFVEGKVYCDNCRTQFVTKLSTYMKGAKVSLECRNREGGTLIYSSDSETDKSGTYRIPVDGDHEEEICEIALKKSSDPDCSEVSKDPFLKKSARISLTKNNGISTPVRLANPLGFMKKKPLPECAKALRELGMNPDDVIQ
What are the official names of this protein?
Olee1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Ole e I family.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_SALCH
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMDDVAPQEKVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: E1B55_ADE12
Sequence: MEREIPPELGLHAGLHVNAAVEGMAEEEGLHLLAGAAFDHAAAADVARGEGGGAEPCGGGEVNMEQQVQEGHVLDSGEGPSCADDRDKQEKKESLKEAAVLSRLTVNLMSRPRLETVYWQELQDEFQRGDMHLQYKYSFEQLKTHWLEPWEDMECAIKAFAKLALRPDCSYRITKTVTITSCAYIIGNGAIVEVDTSDRVAFRCRMQGMGPGVVGLDGITFINVRFAGDKFKGIMFEANTCLVLHGVYFLNFSNICVESWNKVSARGCTFYGCWKGLVGRPKSKLSVKKCLFEKCVLALIVEGDAHIRHNAASENACFVLLKGMAILKHNMVCGVSDQTMRRFVTCADGNCHTLKTVHIVSHSRHCWPVCDHNMFMRCTIHLGLRRGMFRPSQCNFSHSNIMLEPEVFSRVCLNGVFDLSVELCKVIRYNDDTRHRCRQCECGSSHLELRPIVLNVTEELRSDHLTLSCLRTDYESSDEDDN
What is the function of this protein?
Plays a major role to prevent cellular inhibition of viral genome replication.  Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E4orf6.  This viral RING-type ligase ubiquitinates cellular substrates and targets them to proteasomal degradation: TP53/p53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.  Degradation of host TP53/p53 activity is essential for preventing E1A-induced TP53 accumulation that would otherwise lead to cell apoptosis and growth arrest.  E1B-55K also inactivates TP53 transcription-factor activity by binding its transactivation domain.  E1B-55K also functions as a SUMO1 E3 ligase for TP53 which causes the latter to be sequestered in promyelocytic leukemia (PML) nuclear bodies thereby contributing to maximal inhibition of TP53 function.
What are the official names of this protein?
E1B 55 kDa protein, E1B-55K, E1B protein, large T-antigen, E1B-495R.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 55 kDa protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Colocalizes with host TP53 to host PML nuclear bodies. PML localization of E1B-55K is necessary for E1B-55K-dependent SUMOylation of TP53.
Protein: TCTP_TRIPS
Sequence: MIIYRDLFSGDELCSDTFPMKLVNDVVFEFTGKHVVRKLGEVTLEGANPSAEEFDEGTEEQMESGIDIVLNHQLMEMPMYQDIKIFKDWIKEYMKKLVEKMKSDGESEESISKFKKNMQEYVTSLLKKDRFKELQFFSGPGENAAEGQLAIVEYRQVSDTEQPIVMLIKQGLVVEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_MYCPN
Sequence: MNNLKAHYQKTIAKELQKSFAFSSIMQVPRLEKIVINMGVGDAIRDSKFLESALNELHLISGQKPVATKAKNAISTYKLRAGQLIGCKVTLRGERMWAFLEKLIYVALPRVRDFRGLSLKSFDGRGNYTIGIKEQIIFPEIVYDDIKRIRGFDVTLVTSTNKDSEALALLRALNLPLVKG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS19_AERHH
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPVKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTEEMIGHKLGEFAPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y1291_MICLC
Sequence: MSGHSKWATTKHKKAVIDARRAKAFAKYIKNIEVAARAGGPDVAGNPALDLAVSKAKKASVPNDNIDRAVKRGAGLTGEVIDYAEIMYEVRGPQGSALLVECLTDNKNRAAADVRAAVTRNGGTMADSGSVSFLFERKGLVRLPAEGNTEDGLLEAVLEGGADAEEVVLSGDSFEILSDPSDLQSVAKALDEAGVEYESDELEFVPTMKVDLDASGARTFLRLTDALEDLDDVQNVFSNVDIAPEVLAELDED
What are the official names of this protein?
Probable transcriptional regulatory protein Mlut_12910.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_METS4
Sequence: MTPDDLLEEFRAAGALLEGHFILSSGLHSAVFLQKMAIFSDPVRTARVCAGLASVIRDRYGAVDLVVSPAIGGIVPGYETARALGARAIFVERDPGGPFQLRRGFSIPAGSRAVMVEDIVTTGLSSRECLAALRDQPGEVVGAACLIDRSGGRADLGAPLVALATLDIPNYPADQLPPDLAAIPAVKPGSRATTPG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PPR37_ARATH
Sequence: MRGLIQTRLLETGTLRTALFLSCYGRVFSSVSDGKGKVSYRERLRSGIVDIKEDDAVDLFQEMTRSRPRPRLIDFSRLFSVVARTKQYDLVLDLCKQMELKGIAHNLYTLSIMINCCCRCRKLSLAFSAMGKIIKLGYEPDTVTFSTLINGLCLEGRVSEALELVDRMVEMGHKPTLITLNALVNGLCLNGKVSDAVLLIDRMVETGFQPNEVTYGPVLKVMCKSGQTALAMELLRKMEERKIKLDAVKYSIIIDGLCKDGSLDNAFNLFNEMEIKGFKADIIIYTTLIRGFCYAGRWDDGAKLLRDMIKRKITPDVVAFSALIDCFVKEGKLREAEELHKEMIQRGISPDTVTYTSLIDGFCKENQLDKANHMLDLMVSKGCGPNIRTFNILINGYCKANLIDDGLELFRKMSLRGVVADTVTYNTLIQGFCELGKLEVAKELFQEMVSRRVRPDIVSYKILLDGLCDNGEPEKALEIFEKIEKSKMELDIGIYNIIIHGMCNASKVDDAWDLFCSLPLKGVKPDVKTYNIMIGGLCKKGSLSEADLLFRKMEEDGHSPNGCTYNILIRAHLGEGDATKSAKLIEEIKRCGFSVDASTVKMVVDMLSDGRLKKSFLDMLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g12620.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: KAD_COXBN
Sequence: MPLRIILLGLPGAGKGTQADFIAKHLDIPKISTGDMLRAAVKAKTPLGLEVKKIMESGGLVSDEIMIALVKERVKLPDCHKGYLLDGFPRTLAQADALNAAAIKIDLVIEIDVPEEEIIERMTGRLIHPASGRTYHRRYNPPKVADKDDVTGEPLIQRADDREETVRHRLAVYRKQTSPLSDYYAQWEKSGDPQAPKYFRISGLGSMEEVRERILQVFEAYDPRDSGNLEH
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPA_BOVIN
Sequence: MAEGERQTPSDSSEDAPPTTQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLSFEYKVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDQEAENLVATVVPTNLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVMSSC
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity).  Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro).  The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex.  Is involved in apoptosis; the function appears to be independent from PP2A (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator, PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B'.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNC_SALPK
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I35A3
Sequence: MVQEQDTPWILSTGHINTQKGEDGQQTPKLEHRNSTRLMGHCQKTMNQVVMPKQIVYWKQWLSLRNPILVSLKTRVLKRWRLFSKHEWTS
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: TGT_HAMD5
Sequence: MKYQLQKTDGRARLGKLIFERGLVDTPAFMPVGTYGSVKSMTPDEITETGAQIILGNTFHLWLRPGQDVIKLHGDLHDFMQWQGPILTDSGGFQVFSLNSMRKIEEKGVSFRHPLNGSEIFLSPEKSMEIQLDLGSDIVMVFDECPPYPSDLIYMKSSMEMSLRWANRSREHFNNLNNKNALFGIIQGGLSLELRETSLQGLLQIGFDGYAIGGLAVGEPKEEMYRVLDFLCPRIPDNKPRYLMGVGKPENLVEGVRRGIDMFDCVMPTRNARNGHLFVTHGVIKIRNTRYKTDISPLDPDCDCYTCRHYSRAYLHHLDRCNEILGARLNSIHNVRYYQRLMADLRHAIYEERLECFVEEFYKKIGLSIS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RNP4_SACS2
Sequence: MRRKNQIKKRIIELIELAYNTAKSGNLELAREYVKLAEMYSRKGKVEIPLKYKRMFCRKCYTPLIIGVTERRRMRSKILIRTCLICNWQRRYVLSGNKRSDKENES
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_LEPCP
Sequence: MQSNRRDFLKAQALAASAAAAGIPIVVEAANGTAAPKTAADVAVRWDKAPCRFCGTGCAVMVGVQEGKVVATQGDPEAPVNRGLNCIKGYFLSKIMYGRDRLQTPLLRKKNGVYDKEGDFVPVSWDEAFDIMAAKWKETLKTDGPTGIGMFGSGQWTVWEGYAAAKLWKAGFRSNNLDPNARHCMASAVTGFMRTFGIDEPMGCYDDIEQSDAFVLWGSNMAEMHPILWSRITDRRLSNPHVKVAVLSTYEHRSFDLADQAMIFKPQTDLAILNYIANYIITNKKVNTEFVKKNINFKKGATDIGYGLRPGHALEKDATSNGYPGADGKPKGNPNDSTPISFDEYAKFVSEYTAEKVSEISGVTVEQLKALAELYADPKVKVVSYWTMGFNQHTRGTWANNMVYNIHLLTGKISQPGNGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNPEHRHHAEEIWGLPEGTIPDKIGLHAVAQSRALKDGKLKCYWVTTNNNMQAGPNINGEILPGWRNPKTFIVVSDPYPTASAMAADLVLPAAMWVEKEGAFGNAERRTQVWRQQVSAPGEARSDLWQMMEFSKRFKIEDVWTAELIAKKPAVKGKTLFDVLFRNGKVDKYPLADLTKVNAKYIKDYTNDESKAYGFYVQKGLFEEYAEFGRGHGHDLAPFDVYHEVRGLRWPVVDGKETLWRFREGYDPYVKKGEGVKFYGHKDGRANIFALPYQPAAESPDKEYDLWLCTGRVLEHWHTGTMTRRVPELHRAVPEAQLFMHPDDAKARGLQRGMKVKIASRRGEILLAVETKGRNKVPRGLVFVPFFDEGKLINKLTLDATCPISKETDFKKCAVKVVRA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: HEM1_CHLPB
Sequence: MNIISVGVNHKTAPIEIRERLSLSEVQAKEFLTNLIDDGIAQEAMVVSTCNRTELYVVPGMPEVDGNYMKEFLISYKDAQGEVRPEHFFNRFYCNTARHLFEVSSAVDSLILGEGQILGQVKNAYRIAVEVQSAGILLTRLCHTAFSVAKKVKTKTKIMEGAVSVSYAAVELAQKIFSNLSIKKILLVGAGETGELAAKHMFQKNARNIVITNRTLSKAEALAEELGTNQVLPYESYKDHLHEFDIIITAVSSKEYVLTEPELQQSMQKRRLKPVIILDLGLPRNVDPEIGNLKNMFLKDIDALKHIIDKNLEMRKCELPKVKKIIDEELVGFAQWINTLKVRPTIVDLQSKFLEIKEKELERFRYKVSDAELKRMERLTDRILKKILHHPIKMLKAPVDTADTIPSRVNLVRNIFDLEEQNRLSK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: Y4OV_SINFN
Sequence: MSTDTLVKRPTRSELIDRFHSKIRAGEPIIGGGAGTGLSAKSEEAGDIDLIVIYNSGRYRMAGRGSLAGLLAYGNANQIVVDMASEVLPVVKHTPVLAGVNGTDPFVVMPTFLRELKEIGFAGVQNFPTVGLIDGLFRQNLEETGMSYAQEVAMIAEAHNLDLLTTPYVFGPDDAVAMAKAGADILVCHMGLTTGGAIGAQSGKTMEDCVALINQCIKAAREIRDDIIILCHGGPIANPEDARFILGACPGCHGFYGASSMERLPTEEAIKSQTLAFKAIRRKPA
What are the official names of this protein?
Uncharacterized protein y4oV.
Protein: MLAD_ECOLI
Sequence: MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYATFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIRTSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNKNSGDAPAAAPGNNETTEPVGTTK
What is the function of this protein?
Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane (PubMed:19383799, PubMed:27529189).  MlaD functions in substrate binding with strong affinity for phospholipids and modulates ATP hydrolytic activity of the complex (PubMed:27529189).
What are the official names of this protein?
Intermembrane phospholipid transport system binding protein MlaD.
What is the protein family that this protein belongs to?
Belongs to the MlaD family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ACNA_STAAC
Sequence: MAANFKEQSKKHFDLNGQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDFVITDDHIKALSQFGKDGNEGEVPFKPSRVILQDFTGVPAVVDLASLRKAMDDVGGDITKINPEVPVDLVIDHSVQVDSYANPEALERNMKLEFERNYERYQFLNWATKAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVLGWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKYMKLTGRSDEHIALVKEYLKQNHMFFDVEKEDPNYTDVIELDLSTVEASLSGPKRPQDLIFLSDMKSSFENSVTAPAGNQGHGLDKSEFDKKAEINFKDGSKATMKTGDIAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQPYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKANYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPELFIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEPGTIVPLNGLRVMGKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIRIKNQLAPGTEGGFTTYWPTNEVMPIFDAAMKYKEDGTGLVVLAGNDYGMGSSRDWAAKGTNLLGVKTVIAQSYERIHRSNLVMMGVLPLEFKKGESADSLGLDGTEEISVNIDENVQPHDYVKVTAKKQDGDLVEFDAMVRFDSLVEMDYYRHGGILQMVLRNKLAQ
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: SYGB_THIDA
Sequence: MTTANLLVELFVEELPPKALKKLGEAFAAALTESLVAQGLVHAQAAVTHFASPRRLGAHIENVLERSADKPVSTKLMPVSVGLDADGNATPALLKRLAALGADASAVATLRRESDGKAEALFMDSVAKGISLGLGLAKALWESLDKLPIPKVMSYQLADGWSTVNFVRPVHGLVALHGTDPVDVRMFGLTAGRKTHGHRFEAAADPIVLKDADSYAQQLESEGAVIANFAERRAEIVRQLEAAAAPLGLVPVEDEALLDEVTALVERPNVLLGQFEQAFLEVPQECLILTMKANQKYFPLLDAAGKLTNKFLIVSNISPADASAVVGGNERVVRPRLADAKFFFDQDRKKTLDARVLGLAKVVYHNKLGTQGERVTRVQAVARAIGEKLGGEALALKADQAALLAKADLLTDMVGEFPELQGVMGRYYAQHDGVADDVAFAIEDHYRPRFAGDDLPRNPVGVCVALADKLETLVGLFGIGEKPTGDKDPFALRRHALGVVRMLIEKHLPIGLNELVSIAFSAFQQGLLGQAHTDVYLFMFERLSGAMREQGYSANEVDAVLSLNPIRIDLVPQQLEAVRAFAALPEAAALAAANKRVGNILKKAEGEVGASADPGRFVEAAERALFAALDEVAPRAAAAFGSGDYTASLQALAALKAPVDAFFDQVMVNADDPALRANRLALLNQLHRTMNRVADISRLAA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_HAEIE
Sequence: MARSIIAVLPAAGVGSRMQADKPKQYLTLLGKTLLEHTLDVMLSYPAVSKIILAVSKDDPYISTLSLDPKIQLVEGGTTRAESVLNGLNVIAEKNAWVLVHDAARPCLQHADIDKLLAIEDKQGAILAIPVTDTIKRADNQQCIVKTEDRSQLWQAMTPQFFPVDILRDALSTGIQQGANITDEASAIELAGFRPHLVAGRSDNLKVTRPEDLALAEFYLTRNKL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.