PharMolix/UniProtQA huggingface dataset:
Protein: ASSY_FRASN
Sequence: MTERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESIVVDAREEFAASFVAPAIRANALYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTGKGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAEERGLPIDVSKKSPYSIDQNLWGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLVAELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKRGIDQRWGEIVYDGLWFSPLRAALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYDHALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSP_BPAR1
Sequence: MAKINELLRESTTTNSNSIGRPNLVALTRATTKLIYSDIVATQRTNQPVAAFYGIKYLNPDNEFTFKTGATYAGEAGYVDREQITELTEESKLTLNKGDLFKYNNIVYKVLEDTPFADIEESDLELALQIAIVLLKVRLFSDAASTSKFESSDSEIADARFQINKWQTAVKSRKLKTGITVELAQDLEANGFDAPNFLEDLLATEMADEINKDILQSLITVSKRYKVTGITDTGFIDLSYASAPEAGRSLYRMVCEMVSHIQKESTYTATFCVASARAAAILAASGWLKHKPEDDKYLSQNAYGFLANGLPLYCDTNSPLDYVIVGVVENIGEKEIVGSIFYAPYTEGLDLDDPEHVGAFKVVVDPESLQPSIGLLVRYALSANPYTVAKDEKEARVIDGGDMDKMAGRSDLSVLLGVKLPKIIIDE
What is the function of this protein?
Capsid protein that self-associates to form pentons, building the capsid in association with hexamers of the major capsid protein and one dodecamer of the portal protein.  The capsid vertex protein self-associates to form 11 pentons, building the T=13 laevo capsid in association with 160 hexamers of the major capsid protein.
What are the official names of this protein?
Capsid vertex protein, Gene product 24, gp24.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae capsid vertex family.
What are the subcellular locations of this protein?
[Capsid vertex protein]: Virion. Note=Part of the capsid icosahedric shell of the immature virion. The capsid contains 55 copies. SUBCELLULAR LOCATION: [Mature capsid vertex protein]: Virion. Note=Part of the capsid icosahedric shell of the mature virion. The capsid contains 55 copies.
Protein: Y2283_BACC4
Sequence: MKKTFYHYMMKHRAALFRNEISDLAEAMYDDLSFPKQSEDYDEISSYLELSGMLESMSIFDEAWDLYIQDR
What are the official names of this protein?
UPF0346 protein BCB4264_A2283.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: RNH2_CALMQ
Sequence: MGTVNSLEAGIDEAGRGPVIGPMVIAIVGWSNSEAEGIGVKDSKQLTPSGRSRLYKLIVSKAPCVRHVIVEPSEIDYYVNRGLLNELEAIKMSELIKACSGVTRVYVDSPDPNPSRFRGFINVKDVELIVLNHADESIPLVSAASIVAKVIRDTIISRLKETYGDFGSGYPSDPRTISALRRWINNGTLPPIVRRSWRTIKRMTNSRLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPI1_PICST
Sequence: MATKRKKAQKAKDFVKPKLKVGKTAAKPDNHTDTSFTAKTISLPNQSIAKKSKSGVSEEQKQEIDLSHHLSLTKHHASATRKEVLIYIDQHLPSNPSLYKQIFTSIIPLILDQSASVRTTLVALFNKCANMQPGILELHIRSIALFIHSAMTHLHPEIRNSSTKFLNVLVEHAPQSLSKSFFVKTMRSYFTLMSWTLTDDKKSVSLAITTSAAIGGSVKKARIGHLAVLKAFLQASLFPQLSDSAESEINPAIVVSVHPQSYKYLIPAATSQAFAPLKLFANELPNNSKDIDDGKFHISDLDTITAEDLDTRRKVFVDVFQKPVVKNLNSLVKEGGEVGREANSCMTIIDNLEQELKKVAEDE
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_SPOFR
Sequence: MKLNVSFPATGCQKLFEVVDEHKLRIFYEKRMGAEVEADQLGDEWKGYVLRIAGGNDKQGFPMKQGVLTNSRVRLLMSKGHSCYRPRRDGERKRKSVRGCIVDANLSVLALVIVRKGEQEIPGLTDGNVPRRLGPKRASKIRKLFNLSKEDDVRRYVVKRLLPAKEGKENAKPRYKAPKIQRLVTPVVLQRRRHRLALKKKRLAKRKQSENDYAKLLAQRKKESKVRRQEELKRRRSASMRDSKSSDKSAPQK
What is the function of this protein?
Component of the 40S small ribosomal subunit.  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: FOLE_YEASB
Sequence: MHIGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYIKFLFDLMIIKNPLRMVGKTYRDAVTALNSLQSNYANIMAIRQTGDRKNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPSFKQLENVKLGIAGEFQKSNASLAVMLASEILHTSNILEEKIKCSSNASIPEKFIIGLQNTKWEXRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDTVRLSKRKKILLFNQQSRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQESLVKNWNKIDDNRAKTHVTASIEEANELIETLYDEPADIFVTGSLHLVGGLLVVFDRIDVK
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Required for methionine synthesis and maintenance of intact mitochondrial DNA.  Involved in telomere maintenance (By similarity).
What are the official names of this protein?
Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix. Cytoplasm.
Protein: HN_NDVH4
Sequence: MDRAVSQVALENDEREAKNTWRLIFRIAILFLTVVTLAISVASLLYSMGASTPSDLVGIPTRISRAEEKITSTLGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDYIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHLHSHQYLALGVLRTSATGRVFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKATETEEEDYNSAVPTRMVHGRLGFDGQYHEKDLDVTTLFGDWVANYPGVGGGSFIDSRVWFSVYGGLKPNTPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDGEQARLNPASAVFDSTSRSRITRVSSSSIKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGVREARSG
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: RL23_MYCBT
Sequence: MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PPAC_LACLA
Sequence: MSDKILVFGHQKPDTDAIGSSYGFSYLSNHRPNGALNTEVVALGTPNEETQFVLDYFGVKAPRVVKSAKEEGVDTVILTDHNEFQQSISDIEDLTIYGVVDHHRVANFNTAAPLFMTVEPVGSASSIVYRKFLEANVEIPKEVAGLLLSGLISDTLLLKSPTTHVTDHKVAKELAEIAGVNLEEYGLAMLKAGTNLSTKTAEELIDIDAKTFELNGSNVRIAQVNTVDIPEVLERLSDIKAAINASMTANGYDDFVFMITDIVNSNSEIIALGAHPEKSEAAFNFTLADDHAFLAGAVSRKKQVVPQLTESFNK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35B1_CHICK
Sequence: MGANAGRRSRSPERLRLPVCFLGVFACYFYYGILQESITRGKYGDGARQEKFTFALSLVFIQCVINAAFAKLLIRFFDSVRADRTHSWLYAACSLSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTVLRKKYPLAKYLCVLLIVTGVALFMYKPKKGAGGDDHIFGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNVNLWSTLFLGAGILFTGELWEFLSFTERYPSIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISTMQWVGTVLVFLGLGLDAKFGKGVKKTSH
What is the function of this protein?
Probable sugar transporter.
What are the official names of this protein?
Solute carrier family 35 member B1, Endoplasmic reticulum nucleotide sugar transporter 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYB_PTERU
Sequence: MTNIRKTHPLLKIINESLVDLPVPSSVSSWXNXGYLLTACLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWALRYLHANGASMFFICLYIHIGRGMYYGSYMYSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIIAALVVVHLLFLHETGSSNPTGIPSDPDMVPFHPYHTIKDILGILAMLTLLSMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVIPLLHTSKQRTMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPYIIIGQMASIMYFTIILVLMPATSMMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YP7_AGRT9
Sequence: MNFADTPLASLDLDWACEEFIKTYGASPQLETGEVIQTNNGLLYLYGKGSLSQRIHDTHLKFKEKEELSFTTIKPAEMKAQQSDLTYYVAIFQSNYFLCVSNPEKGFLRCHNRPFLYPIVAHGSMS
What are the official names of this protein?
Uncharacterized protein 7, Open reading frame 3.
Protein: SSUB_BURP1
Sequence: MTGTTLAATYGPISGADLEAELAQPRIADGDAQDAAVYERDGGAHAPPFASGGAPPDGDRADVRRAAGAGDASVRLTRVSKRYGERAVLADVDLSIGRGSFVSIVGRSGCGKSTLLRLVAELETPSAGTLVKRGDGGGALDTRIMYQEARLLPWKTVLQNVMLGLGRRAKDDARAVLDEVGLLARANDWPAQLSGGQRQRVALARALVHRPQLLLLDEPLGALDALTRIEMHALIERLWREHRFTALLVTHDVQEAVALADRVLLIEAGRIAFDQRVPLDRPRARASAAFAALEDRVLQRVLTGSDAAPAAPNAAGPEGASRGRAAPASGLRWAV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RAS1_DROPE
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLTTWNVKNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKLNKPNRRFKCKIL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ISG20_MOUSE
Sequence: MAGIPEVVAMDCEMVGLGPQRVSGLARCSIVNIHGAVLYDKYIRPEGEITDYRTQVSGVTPQHMVRATPFGEARLEILQLLKGKLVVGHDLKHDFNALKEDMSKYTIYDTSTDRLLWHEAKLQYYSRVSLRLLCKRLLHKNIQVLPGSLLGVGGCILPGTDILHLLLYVGMVRIADLRLLTPFLPPSCLACPLLPESLASARSHAVISALSSSSHLLTPLPNPSQGPQGHVDRLSGQLQDWGGSPLAPALPVSAEQLAGPLLCGRCQGHNGALQNLSATQSPARAALPWDVRLNFILIQG
What is the function of this protein?
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA.  Exhibits antiviral activity against RNA viruses in an exonuclease-dependent manner.  May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis (By similarity).
What are the official names of this protein?
Interferon-stimulated gene 20 kDa protein, Promyelocytic leukemia nuclear body-associated protein ISG20, Protein DnaQL.
What is the protein family that this protein belongs to?
Belongs to the exonuclease superfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.
Protein: LEXA_BURMS
Sequence: MIKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDAPHQLTLPHAALMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFSSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLKRRPGGVELIAENPDYENIFVKAGSAEFALEGIAVGLIRPGEF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HDOX1_STAAE
Sequence: MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing) 1, Heme-degrading monooxygenase 1, Iron-regulated surface determinant 1, Iron-responsive surface determinant 1.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_STAA8
Sequence: MHFIAISINHRTADVALREQVTFRDDALRIAHEDLYETKSILENVILSTCNRTEVYAVVDQIHTGRYYIQRFLARAFGFEVDDIKAMSEVKVGDEAVEHLLRVTSGLDSIVLGETQILGQIRDAFFLAQSTGTTGTIFNHLFKQAITFAKRAHNETDIADNAVSVSYAAVELAKKVFGKLKSKQAIIIGAGEMSELSLLNLLGSGITDITVVNRTIENAMKLAAKHQVKYDELSSLPNLLESADIVISSTSAQSYIITNEMIERIAENRKQDSLVLIDIAVPRDIEPGISAITNIFNYDVDDLKGLVDANLRERQLAAATISEQIPTEIHAHNEWISMLGVVPVIRALREKAMAIQAETMDSIDRKLPGLSERERKIISKHTKSIINQMLKDPIKQAKELSSDKKSNEKLELFQNIFDIEAECPHEQAKQQKESKVKEISARRIFSFE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LSPA_SYMTH
Sequence: MLSIVLAIVAVVVDQVTKWLVATRMALHSEIEIIPGFFSLQYVHNTGAAFGMLRNGRWFFVAVAALAVAGILYYLRQPESRHPLLRVALGLVMGGAVGNMIDRIATGRVVDFLLFYWRDYYFPNFNVADICVTVGVGLLFLHLVLVERKGTA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10_SYNS3
Sequence: MGRTLESKQQIVEELKKLLGEAEMALVLDYQGLSIKEMSDLRTRLQASNGVCKVTKNTLMRRAIDGDSVWSSLDSLLNGTNAFVLIKGDVGGAVKAVQSFQKETKKSETKGGLFEGKLLSQDEIKAIGELPSKEVLMAQIAGAINAVTTKVAVGVNEVPSGLARALKQHADSGES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GET1_HUMAN
Sequence: MSSAAADHWAWLLVLSFVFGCNVLRILLPSFSSFMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGVGITCWILVCNKVVAIVLHPFS
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER) (PubMed:21444755, PubMed:23041287, PubMed:24392163, PubMed:27226539).  Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (PubMed:21444755, PubMed:23041287, PubMed:24392163, PubMed:27226539).  Required to ensure correct topology and ER insertion of CAMLG (PubMed:31417168, PubMed:32187542).
What are the official names of this protein?
Guided entry of tail-anchored proteins factor 1, Congenital heart disease 5 protein, Tail-anchored protein insertion receptor WRB, Tryptophan-rich basic protein.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YBJL_SALTI
Sequence: MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFRNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGISNGLGAVGGQMLIAGLVVSLIPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAU10_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKVGIYTIAN
What are the official names of this protein?
Seripauperin-10.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: RL1_UREP2
Sequence: MAKISKKLFAAYEGIDKQKAYPLFDAIKLAQEKSITKFDGSINIAIKLNLDTTKVEQQLRGSISLPNGNGKNVRVLVLSEDITKEEAASVGADYFGGADYIQNIEKMLNQIDVIITNQKMMPLLAKLGKVLGPRGLMPNPKIGTVTNDVLKAVEEFKRGRIEYRTDTYGNIHMSIGRVSFETTKIEENANALLNLIKSKKPATVKGQYIQNIAVSPTMGPGIKVVINNN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RN141_HUMAN
Sequence: MGQQISDQTQLVINKLPEKVAKHVTLVRESGSLTYEEFLGRVAELNDVTAKVASGQEKHLLFEVQPGSDSSAFWKVVVRVVCTKINKSSGIVEASRIMNLYQFIQLYKDITSQAAGVLAQSSTSEEPDENSSSVTSCQASLWMGRVKQLTDEEECCICMDGRADLILPCAHSFCQKCIDKWSDRHRNCPICRLQMTGANESWVVSDAPTEDDMANYILNMADEAGQPHRP
What is the function of this protein?
May be involved in spermatogenesis.
What are the official names of this protein?
RING finger protein 141, Zinc finger protein 230.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: ICK20_TRILK
Sequence: MMKYFLVLCLVVLGVAAVQAAALEDEKFLNLAESLAMPEESRCKARRYGCTDKAECCSEKCAYPALTCAFNWSCEKVCA
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Toxin ICK-20.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 13 (insecticidal toxin ABC) family. ICK-21 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRCA_ECOSE
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: SCX5_TITPA
Sequence: MSIFPIALALLLIGLEEGEAARDGYPISKNNYCKIYCPNTKVCKETCKNRASAPDGECDGWNLCYCFKVPDNIPVWGDPGTPPCMT
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Tpa5, T-alpha* NaTx7.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_COXBN
Sequence: MFPLLGLFGGTFDPIHKGHLALANELIQKLPSLTEIQFIPSRQPPHRPSPLASPANRLEMIKRAIANQPNLILNDVEIKGNDISYTINTLKILRPLFLTHALCFILSTDAFADFKHWHQSSVILEYCHLIVVNRPNYRLPQQPWLSDLLSHHQTENAEDLGRFQFGKIFFQTLSPRPISATQIRHYLAKGDYEIVAPLLPKTVLAYIKAHKLYQQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ENO_SERP5
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAVLGKDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLAAAKAAAASKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKSLKEAVRIGSEVFHHLAKVLKAKGLNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDVTLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSRAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.