PharMolix/UniProtQA huggingface dataset:
Protein: EFMT1_DANRE
Sequence: MSQFWYSEETASRLAEELLQQAGEHGRIACLSAPSVYQKLKQLESVRSDGVSAVLLEFDRRFAAYGDEFVFYDYNNPLCLPEDLLPQSFDIVIADPPYLSEECLSKVTLTVKHLTKGKILLCTGAIMEEHAGKLLDLKMCSFLPRHNHNLANEFRCYVNYESRLLS
What is the function of this protein?
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
What are the official names of this protein?
EEF1A lysine methyltransferase 1, N(6)-adenine-specific DNA methyltransferase 2, Protein-lysine N-methyltransferase n6amt2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHF1_STAAR
Sequence: MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTYBC_VIBVY
Sequence: MAKITQTMISQLLAAVGGSSNVSKCGNCMTRLRLTLANNGVADQAVIKQIPGVMGVVESDEQFQIILGPGKAQQAAELMNKLIESVINGDVQEQAMASDTNDLSSVAAEQKKQMKSKQTSAVQRFLSKFATIFTPLIPGFIAAGLLLGFATLLEQMFVLEQTPSQFILDLIAYMKVFGKGLFAFLSILIGYNAQQAFGGSGVNGAILASLFVLGYNPDATSGIYSGMSEFFGYTIDPRGNIIGVLLAAIIGAQVERKVREYMPDDLDMILTSVVTLLIMGVVTFVVIMPIGGELFKGMSWLFLNLNDNPLGAAILAGLFLISVVFGIHQGFVPVYFALMEAQGFNSLFPILAMAGGGQVGASLALYFKAKKDAVLRTQVKGAIIPGILGIGEPLIYGVTLPRVKPFVTACIGGAAGGFFIGLVSYLGLPVGLNTVFGPSGIVAIPLMTSHSGIFAGMAVFVVGLLISYVVGFLATYFFGSKDVDLS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_THIDA
Sequence: MAPELRLAVQFASGADDLPSRAQIRRWVAAALEHDAEITVRIVDADEAQALNRAYRDKDYVPNVLTFEYGEIAPALLGGDVVICAPVVEREAREQGKPLGHHYAHMTVHGVLHLQGYDHVDAADAERMETREAAILKRFHIPHPYHS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_PASMU
Sequence: MPKRTDINTILIIGAGPIVIGQACEFDYSGAQACKALREEGYKVVLVNSNPATIMTDPDMADVTYIEPIEWRTVEKIIEKERPDAILPTMGGQTALNCALDLSKNGVLKKYNVELIGAKEDAIDKAEDRGRFKEAMEKIGLSTPKSFVCHTLEEAWAAQSEVGFPTLIRPSFTMGGSGGGIAYNKDEFYAICERGFDASPTHELLIEQSVLGWKEYEMEVVRDKADNCIIVCSIENFDPMGVHTGDSITVAPAQTLTDKEYQIMRNASIAVLREIGVDTGGSNVQFAINPENGEMIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLNELRNDITGGLIPASFEPSIDYVVTKVPRFAFEKFPQADDRLTTQMKSVGEVMAMGRTFQESLQKALRGLETGICGFNLMSEEPEKIRQELGNPGPIRILYVADAFGAGFTLDEVHHYSKIDPWFLIQIQDLVLEELALEKRTLDDLDYAELRRLKRKGFSDKRIAQLTKSAESAVRNKRVSLNLHPVYKRVDTCAGEFTSDTAYLYSTYEEECESRPSDKKKIMILGGGPNRIGQGIEFDYCCVHASLALREAGFETIMVNCNPETVSTDFDTSDRLYFEPLTLEDVLEIIHVEKPHGVIVHYGGQTPLKLANDLHANGVNIIGTSADSIDAAEDRERFQQILHKLHLKQPTNRTARNAEEAVKLAEEVGYPLVVRPSYVLGGRAMQIVYNVDELQRYMREAVSVSNDSPILLDHFLNNAIEVDVDCICDGAEVVIGGIMQHIEQAGIHSGDSACSLPPYSLSQEVQDEIRRQTAEMAFALGVKGLMNVQFAVQDGVIYVLEVNPRASRTVPFVSKATGRPLAKIAARVMAGESLKAQGIQGEVIPPFYSVKEAVFPFIKFPGVDTVLGPEMRSTGEVMGVGTTFAEAFLKAQLGANERIPKTGKVFLSVNDADKPRLLPIARQLQESGYGLCATLGTAKFLREHGVAVQIINKVREGRPNIVDAIKNGEIAMVINTVSGLAETVTDGHAIRRSALQQKVFLQTTLAGAEALAGSVEYLADSEVYSLQDLHQRLL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: Y3184_PSEPW
Sequence: MSENQTADEGRFSSTEIRILGALIEKQATSPESYPLTLNALVLACNQKTSREPVMNLTQGQVGQALRALESQDMTRLQMGSRADRWEQRVDKALELVPAQLILMGLMFLRGPQTLNELLTRSNRLHDFDDTEQIQHQLERLISRGLALHLPRQAGQREDRYTHALGDPAEIEQILAARQQEGGARSSGGNVSEERIEALEARIAALEARLAELEG
What are the official names of this protein?
UPF0502 protein PputW619_3184.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: OTC_VIBS2
Sequence: MENLLSVKDLSKQQILDLLALAKAVKANPAEYSQALAGKSIVTIYEKPSLRTRVTFDIGIHKLGGHAVYLDAQNGAIGERETVKDFAANISRWADAIVARVVSHKTLEGLVEHGSVPVVNSLCDLYHPCQALADFLTISEHYEDVSKVKLAYVGEGNNVTHSLMLTGAILGAEVTAVCPRGSSPDAQIVKQAMALAEISGGKINVTDNLDAIVDYDVIYGDTWVSMGDDTPLAQVKEKYMPYQINKALLMRTGIKHVLHCQPAHRELEITSEVMDGEHSLIFDQAENRMHAQNAVLLTLLK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUS1_DICDI
Sequence: MKFKAKISKASILLKTVQNIMKIYNECICHITPDKLRFIIQSDFNDGMQVFCEIQRSLIFENFTIESLSDNEIQFQLDLESLRRVLQSATSNGVSDIFTNLTKVRGGPVLHFIIKSGTSGTVIFQDIPIVLLTAQQMAQINEPTLPDPLVHILLPNLKNLQKVIDKMKNISDCLKIMIAMNNRLSFEVETSSGSISTFYSGLDHPQFGDHVLSPDLQATVCVDIKKFAKVLHIHQLKPSEVVLCLYERSIIVHVVLTDIMITYYLPVLIKN
What is the function of this protein?
Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication.  It is also required for the response to DNA damage (By similarity).
What are the official names of this protein?
Checkpoint protein hus1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HUS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: VATE_CHLMU
Sequence: MADLSAQDKLKQICDTLREETLKPAEEEAGSIVHNAREQAKRIVEEAKEEAQRIIRSAEETASQTLKKGEAALVQAGKRSLENLKQAVETKIFKESLVEWLDGVTTDPGVSAKFVQALVQTVETQGISGNLSACIGKHVSARAVNEALGKEITSKLKDKGVVIGKFSGGAQLKVEERNWVLDISSEALLDLLTRFLQKDFREMIFQSC
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: RL3_LEUMM
Sequence: MTKGILGRKVGMTQVFTESGELIAVTAVEATPNVVLQVKNAETDGYSAIQLGYQDKRTVLSNKPEQGHASKANTAPKRYVREIRNAGDEFNVGDEIKVDTFQAGEYVDVTGITKGHGFQGAIKRLGQSRGPMTHGSRYHRRPGSMGAIINRVFKGKLLPGRMGNNKRTMQNIAIVHVDVENNLLLLKGNVPGANKSLLTVKSTVKVNAKHPEVKMANASASATNSEEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LMBD1_PODAN
Sequence: MLASAGLLQTSLIWVAYAVAVALVLLVAIITTFTWQSPHERSVTVSIVAIVSLTSLLATVFLLPVDIALVSSTASAHLGAKKDWATPERIDGILLTLKVVYYTLYSFDALLCLIVIPFAYFWYEEYDEVEEEEGTSGAGARFWKAAKYTLGFVFLVLILFLLGFFVPAAGSGNGKHLDLDYFKRLLAANKGEKALTFGVGLLITLGTFLYTLYTGAGLALLPVSLIKSAPSISAPQLSATIATDLEHNRELQRQIEMRNAGRPDGISQKDRRELDALLREERTLVRRERLAAETRGDGRSGVFRAWTKIQAVFRPLKLLGGILLLLLSILVWASMLITGIDKAANSICKEHCGYILGHINVFQPVNWIFVQSAKAFPVDYILMALLVLFFFGSSITGIATIGIRFLWVRVFQIKKGRTSPQALLIATVMLALIILAINYAIAMIVAPQYAIYGTQTFCVNAPRHPGEQPDCREHRDMVRPCSEVFSEPAAKDVCTPTVMSTFLNRVTINWPVFGAIDFWAQFAFLGVFMVVFVTSLFRTPRLNLSELDEEAEVDEEEGLLASTGRRFGATWGDITGRAKNRNGYGTGGGEGSNGRG
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: SYQ_SALPK
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSDYFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRADFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPSLKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLS24_STRP3
Sequence: MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLGVNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVEEEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKASVDNGVEKLQDQKAEPRVK
What are the official names of this protein?
Stress response regulator gls24 homolog.
What is the protein family that this protein belongs to?
Belongs to the asp23 family.
Protein: END8_SALHS
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQLVTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PACC1_BOVIN
Sequence: MIRQELSTSYQELSEELDQVVENSEQADERDKETVKVHGPGILPALDSESASSSIRFSKACLKNVFSVLLIFIYLLLMAVAVFLVYQTIMDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHYYEVIPPLRSPGQPGDVNCTTQRVNYTDPFSNQTLKSALIVRGPREVQKRELVFLQFRLNQSSEDFSAIDYLLFSSFQEFLQSPDRAGFMQACESAYSSWKFSGGFRTWVKMSLVETKEEDGREAVEFRQETSVVNYIDQRPAAEKSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRRRYLKKRGQATNHIS
What is the function of this protein?
Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH.  Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling.
What are the official names of this protein?
Proton-activated chloride channel, PAC, Transmembrane protein 206.
What is the protein family that this protein belongs to?
Belongs to the proton-activated chloride channel family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_SALPC
Sequence: MNDVSKASLPKAIFLMGPTASGKTALAIALRKVLPVELISVDSALIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCATRQLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: LUCI_OPLGR
Sequence: MAYSTLFIIALTAVVTQASSTQKSNLTFTLADFVGDWQQTAGYNQDQVLEQGGLSSLFQALGVSVTPIQKVVLSGENGLKADIHVIIPYEGLSGFQMGLIEMIFKVVYPVDDHHFKIILHYGTLVIDGVTPNMIDYFGRPYPGIAVFDGKQITVTGTLWNGNKIYDERLINPDGSLLFRVTINGVTGWRLCENILA
What is the function of this protein?
Catalytic subunit of oplophorus-luciferin 2-monooxygenase.  Oxidoreductase that converts coelenterazine (the oplophorus luciferin) to coelenteramide under emission of blue light with a maximum at 454 nm.  Is also active with bisdeoxycoelenterazine.
What are the official names of this protein?
Oplophorus-luciferin 2-monooxygenase catalytic subunit, 19kOLase.
What are the subcellular locations of this protein?
Secreted.
Protein: HMDY_METJA
Sequence: MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLAEPNKNIMSDDLWKKVEDAGVKVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPENAVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVPGTPQHGHYVIGGKTTDGKELATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAPKKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQNLDETLKAEVEKAEIKPTTLVAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH
What are the official names of this protein?
H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338.
What is the protein family that this protein belongs to?
Belongs to the HMD family.
Protein: YTCB_PSESQ
Sequence: MHSSKCPDLANIGRRRVLAGIALAMTTSSTRAQRLDAFPSRPITWVVPFPPGGAVDAIARIISRKMSESIGQQVVVDNRAGSGGIIGSDLVAKAPSDGHTILINSTGLVVDRFFYPRVPYQSDRDFVPVVLAATLPSVLVVPADSRFRDITQLLKAARENPGKLSFASAGLGTSIHLASALLAARANVELLHVPYRGSSPAVSDLVAGRVDMMIDSVTSQRQNILAKRVRALGVTSLDRHPQLPEVPTIAEAAGLPGFEVLTWCGVFAPKGTPRSVVERLNAEINKAIAAPDVVEALKQLGIKTAGGAPEVLADLFKSETERWQKLIVEYRLNANQ
What are the official names of this protein?
UPF0065 protein in tcbD-tcbE intergenic region.
What is the protein family that this protein belongs to?
Belongs to the UPF0065 (bug) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ISPE_HELPJ
Sequence: MTHVFEVYPKVNVFLKILHKEGAYHKIISRMCLVKNKLKDIISVKNALSFSLKGDFDCPLEENSLFKALQVLKKFLVQKNFSHSVIKSLDTLAIEVEKNIPTQAGLGGGSADAGGLLYHLNQMFDWRLSLKELYTMGSLVGADTNFFISQYKSANATSYGEVIENFEEESLEDRLEIYAPNHVFCSTKAVYQAYKPETCFFQAKEWLKKTSLECLKTYDRNELNDLLKPALRTNPALKDIESQLSKEWFFSGSGSAFFRLKNTQKGANETHCQQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: DPOL3_SACSH
Sequence: MIKDFFILDFSYEIKDNIPLIYIWSIDDEGNSCVVVERNFKPYFYVVYEGNGDEIIENIRKNCEVLLITKVKRKYLGNVVDALLVQTFTPTQIKRCREKISRINGIKSIFDADIRFTMRYSIDFDLRPFTWFKAEVSEVKLEGFRAKKVYILDKILSHYEGKIPELRAIGIDFQIYSKYGSLNPRKDPIVVLSLWSKEGSMQFSLDESMDDLKIIRKFVDYILNYDPDIIYVFDVDVFHWKYITERANSLGVKIDIGRKIGSEVSQGTYGHYSISGRLNVDLVGLLMNERLTGHIDLIEVANYLGISPKRDSLNWYEISRYWDDEKNRDLVKQYSLENAKSIYLLGNFLLSPYSELVKIIGLPLDKLSVASWGNRIEASLIRTAAKSEELIPIRMDNPNRSSKIKKTVIEPKIGIYSDVYVLDISSVYLSVIRKFNISPDTLVKGQCDDCYVSTISNYKFKKEPSGLYKTFLEELSNIQDTRKSKVIEELMSSFYDYIHWINSRWYSREIASAVDELSYEIGKLVIDLIKNSGFEVILANDFLVFVKGGSGDKLNELIFKINSLYDLNLKVRKIYRSLLILGNDRYAGLLEGDKIDIARIGKEDRDLCELVRNVKRKVVEEILISKDVKKAVKLVKSAVIKLRRGEFDIGELITWVHIEKDFSEYDKQLPFVVAARKAIQSGYLISKDSRIGYLIVKGHGSVHDRAEPFFFVKEKNRIDIEYYVDQLLRESLKVLTPLGVSEESLKKTNITDILDMFGASKKK
What are the official names of this protein?
DNA polymerase 3, DNA polymerase B3, DNA polymerase III.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: DEOB_BRASO
Sequence: MRALIVVMDSVGIGGAPDAAGYGDEGADTVGHIAEACAAGQADSDQRQGPLQLPHLAALGLGEACEHATGRRPPGLQQKAGAGAAFGCASERSRGKDTPSGHWEIAGVPVPFEWGYFPKTVPAFPPDLIDQLCASAGLTGILGNRHASGTDIISDLGEAHLQTGQPICYTSADSVFQIAAHEEAFGLDRLYRLCEATRPLVDRFNIGRVIARPFVGRSASGFRRTANRRDYAVPPPEPTILDLATAERRHVVTIGKIADIFAHRGTGHNLKGDSNDTLFTRMLEGLDALDDGGLLFANFIDFDTLYGHRRDVAGYASALEAFDARLPELLDALRDDDLLVITADHGCDPSWSGSDHTRERVPVLIVNGRSAGSIGARTSFADTGATIAQHLQLPPTRHGNSFWPNGA
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_LACH4
Sequence: MVKYPSGSLAAFRKPINKKENEIRHTYTHRKGVNFSDRGMTLEQQINESNKYYLNEEIAVVHKKPTPIQIVKVDYPKRSKAVIREAYFRQASTTDYNGVYKGYYLDFEAKETRNKTNFPLKNFHEHQIFHLSACLKQKGFCFTIIRFASLERYFVTPASFVINAWREKDKSSMTLKEIEDNSYEIKSGFRPTLPYLKAVDNFIADREREL
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP2L_MOUSE
Sequence: MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTDRGRRGRGRGRGSSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAPGAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSSMENDSSNLDPSQAPSLAQPLVFSNSKQNAISQPASGSTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSSTMMEVFLQEKPPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKTSLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSESPSTSSIPSLNETVPAASLLTTANQHSSSLSGLSHTEEIPNTTTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage (By similarity).  Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) (PubMed:25185265).  Required for efficient formation of stress granules (By similarity).
What are the official names of this protein?
Ubiquitin-associated protein 2-like, RNA polymerase II degradation factor Ubap2l.
Protein: OGG1_YEAST
Sequence: MSYKFGKLAINKSELCLANVLQAGQSFRWIWDEKLNQYSTTMKIGQQEKYSVVILRQDEENEILEFVAVGDCGNQDALKTHLMKYFRLDVSLKHLFDNVWIPSDKAFAKLSPQGIRILAQEPWETLISFICSSNNNISRITRMCNSLCSNFGNLITTIDGVAYHSFPTSEELTSRATEAKLRELGFGYRAKYIIETARKLVNDKAEANITSDTTYLQSICKDAQYEDVREHLMSYNGVGPKVADCVCLMGLHMDGIVPVDVHVSRIAKRDYQISANKNHLKELRTKYNALPISRKKINLELDHIRLMLFKKWGSYAGWAQGVLFSKEIGGTSGSTTTGTIKKRKWDMIKETEAIVTKQMKLKVELSDLHIKEAKID
What is the function of this protein?
DNA repair enzyme that incises DNA at 8-oxoG residues.  Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA.  Has a beta-lyase activity that nicks DNA 3' to the lesion.
What are the official names of this protein?
N-glycosylase/DNA lyase.
What is the protein family that this protein belongs to?
Belongs to the type-1 OGG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAP2_YEAST
Sequence: MGAKSVTASSSKKIKNRHNGKVKKSKKIKKVRKPQKSISLNDENEVEILPSRNEQETNKLPKDHVTADGILVLEHKSDDDEGFDVYDGHFDNPTDIPSTTEESKTPSLAVHGDEKDLANNDDFISLSASSEDEQAEQEEEREKQELEIKKEKQKEILNTDYPWILNHDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELGGKESRNNLYSLASHLKKKNLATEVEVVAKARVPIIKFVEPHSGIHIDVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGGLGGFSIICLVFSFLHMHPRIITNEIDPKDNLGVLLIEFFELYGKNFGYDDVALGSSDGYPVYFPKSTWSAIQPIKNPFSLAIQDPGDESNNISRGSFNIRDIKKAFAGAFDLLTNRCFELHSATFKDRLGKSILGNVIKYRGKARDFKDERGLVLNKAIIENENYHKKRSRIIHDEDFAEDTVTSTATATTTDDDYEITNPPAKKAKIEEKPESEPAKRNSGETYITVSSEDDDEDGYNPYTL
What is the function of this protein?
Catalytic subunit of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information.  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met.  Polyadenylates RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome.  TRF4 is also required for proper nuclear division in mitosis, DNA damage repair and sister chromatid cohesion.  Involved in the regulation of histone mRNA levels.  May mediate mitotic chromosome condensation.
What are the official names of this protein?
Poly(A) RNA polymerase protein 2, DNA polymerase kappa, DNA polymerase sigma, Topoisomerase 1-related protein TRF4.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TA2R1_CHLAE
Sequence: MLESHLIIYFLLAVIQFLLGTFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYINVVVIFLIEFITCSASCAFLVFVNELELWLATWLGVFYCAKVASVLHPLFIWLKMRISKSVPWMILGSLLYVSMICIFHIKYTGFMVPYFLRNLFFQNATIQTEVKQAIQIFSFVAELLVPLLIFLVAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAHISALLSILSFLILYISHYLIKTFLSSLKFHVKRFVFLFCILVIGTYPSGHSLILILGNPKLKQNTKKFLCHSKCCQ
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 1, T2R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MENE_BACCZ
Sequence: MMETMPNWLMQRAFLTPDRTAIEMEEEKVTFMQLHEKVVSVCEHLTHVGVKRGQKVAVLMKNGMEMITVIHALSYVGAVAVLLNTRLSREELLWQMDDAEVICLVTDQDFEAKDIPVYSFAEVMNGPKEEASIQEEFSLKEAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSFNLGLRDDDCWLACMPMFHVGGLSLLMKNIMYGMRILLVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGEETYPPSLRCMLLGGGPAPKPLLEACVEKRIPVYQTYGMTETSSQICTLSADYMLMKVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRETIQNGWLHTGDLGYLDEEGFLYVLDRRSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWGQVPAAFVVKSGEITEEEILHFCEEKLAKYKVPKKAWFLEELPRNASKKLLRRELRQLVEEM
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.