PharMolix/UniProtQA huggingface dataset:
Protein: ASNA_NEMVE
Sequence: MAEVRPAADDFESLEPSIKNIVEQDSLKWIFVGGKGGVGKTTCSCSIAVQLALTRRSVLIISTDPAHNISDAFDQKFSKVPTLVKGFQNLYAMEIDPNLGFSNLPEDYFEGPDMMSMGKAMISELLGAFPGIDEAMSFAEVMRLVNSMDFSTVIFDTAPTGHTLRLLSFPSVIEKSLGKILSLKNSISPFISQFGSLLGMQDLNADQMTSKLEETLPVIKQVSAQFKNPDHTTFVCVCIAEFLSLYETERLIQELTKSEIDTHNIIVNQLVFPSKREECNLCEARYRIQHKYLDQIQDLYEDFHVTRLPLLTHEVRGVDKILNFSSNLVTPYKP
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: AT1B2_RHIMB
Sequence: MAALTQKKTCSQMMEEWKEFMWNPRTREFMGRTGSSWALILLFYVVFYAFLTAVFSLSLWVMLQTIDEYTPKYADRLANPGLMIRPKMDTTEVVYSTNGMNGTWQAYVDNLNSLLKDYNKTVQMERGVNCTPGVYNMQEDTGDVRNNPKKACWFFRDVLGDCSGVSDTTYGYQDGKPCVLIKMNRVINFLPVPIKELSNTSITIKCTAQNNDDLLGSIQYFPSVNNQSLGAIDLMYFPYYGNRAQQNYTQPFVAVKFLNATKGVDHMVECRVNAANINNQDPRDLYQGRVIFTMKIDRL
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The exact function of this glycoprotein is not known.  Some specific sequence of the beta subunit can modulate the activation of the Na,K-pump by extracellular potassium ions.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-2, Beta-B1 chain, Sodium/potassium-dependent ATPase beta-2 subunit.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NIKR_BRUME
Sequence: MQRITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQMEACVGVLSYTYDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKSKTDDVRHFADHVKAERHVTHGTLAVLPL
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel (By similarity).
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: Y1954_ARCFU
Sequence: MERAVDIVEKLKGGEIKPAELVEECLEKIERLNPKINAFVTLNEKAIEEAKKADVSTPLAGLPIAIKDNVETRGIRTTYCSKFYENYVPEEDAVLVERLKKAGAVIIGKTNMPEFGLIAYTDNPMFGPTRNPWDLSRTVGGSSGGSAAAVAAGILPVASGNDGGGSIRIPASFCGLYGLKPSFGRVPCYPSLPIFIGLHSEGFLTRYVEDTALMLDLVKGWDIRDVKSLPDEEFSYLKAIEEHPDGVRIAFSPDLGYAIVDPEVEEKVREAAFKLEKFGEVEEVKLSLPNLEQELVTKVVLEVVTFIGDRMAEWEKVAFPPYLGFMALAQSLTFREYIKIEERKMELWKALRGIFEEYDYLITPTVACKPFEIGKLGPEEIAGKAITPIGWMPFTYPFNFTGQPAASIPAGFSKEGLPIGMQIVGKPYDDVGVLKVSKAFQDVSPWQDRYPEL
What are the official names of this protein?
Putative amidase AF_1954.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: RNH3_STRMU
Sequence: MNTFVLQLDEETIQHLIQTLKEYQVQNANPYIRFAAKFKQATILIYASRKVVFQGKNASAVAQELGYKPVVHKSNQDNIKNKQDCSLIGSDEVGNGSYFGGLAVVASFVKQADHAFLKELGVDDSKNLTDVKIKQIAPLLEAKLPHKALLLSPQKYNEVVGDNKLHNAVSVKVALHNQAIFLLLQEGWQPDKIVIDAFTSPKNYQKYLKNENNRFSNPLTLEERAEGKYLAVAVSSIIARKLFLDNLDELSQKVGFNLPSGAGQQSDKIASQILKTYGELGLETTAKLHFKNTKKAYQLLKKE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLIG1_MOUSE
Sequence: MYYAISQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSSSSSSTASLLPKPAREKAEAPLAEPRGPAPESGGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGDGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFSLPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK
What is the function of this protein?
Promotes formation and maturation of oligodendrocytes, especially within the brain.  Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
What are the official names of this protein?
Oligodendrocyte transcription factor 1, Oligo1, Oligodendrocyte-specific bHLH transcription factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KGUA_DEHM1
Sequence: MMTNWNFNKANKPLLLVVSGPSGVGKDAVLARMKERKLPLAYIVTTTTRTKREKETEGVDYNFIRPAEFQQLIGQNELLEWANVYGNFYGVPKAPIRQALAHGFDVIVKVDVQGAASIKKIVPNAVFIFLMPPDMDELTRRLEHRLTESPESLKRRLATAPLEIEKLPDFDYVVVNPEGEIDNAVSEIMSIISAEHCRINPRSIEL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_MALP2
Sequence: MAISQELKASLVKKYGGNSNNTGKVEVQIAILSAEIESLTKHIVANKKDQISKRGLFQKVSKRRSLLSYLKNTDIVRYRQILKDLDIRGN
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FMT_BACC7
Sequence: MIKVVFMGTPDFSVPVLRRLIEDGYDVIGVVTQPDRPVGRKKVLTPTPVKVEAEKHGIPVLQPLRIREKDEYEKVLALEPDLIVTAAFGQIVPNEILEAPKYGCINVHASLLPELRGGAPIHYAIMEGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKTVPLLIQGKLEPIKQNEEEVTFAYNIKREQEKIDWTKTGEEVYNHIRGLNPWPVAYTTLAGQVVKVWWGEKVPVTKSAEAGTIVAIEEDGFVVATGNETGVKVTELQPSGKKRMSCSQFLRGTKPEIGTKLGENA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL31B_STRP6
Sequence: MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ATPA_TETOB
Sequence: MSMRTPEELSNLIKGLIEEYTPEVKMVDFGIVFQVGDGIARIYGLDRVMSGELLEFEDGTLGIALNLEANNVGAVLLGDGLKITEGSRVRCTGKIAEIPVGENYLGRVVDALARPVDGKGAISTNDTRAIESPAPGIVSRRSVYEPLQTGLVAVDAMIPIGRGQRELIIGDRQTGKTAIAVDTILNQKGKGVICVYVAIGQKASSVAQVLNSLKERGALDYTIIVMANANEPSTLQYLAPYTGATLAEYFMYTGRPTLTIYDDLSKQAQAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDALGEGSMTALPVVETQEGDVSAYIPTNVISITDGQIFLSGDLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGTLKLSLAQFAELEAFSQFASDLDAATQKQLARGSRLREILKQPQNSPLSVEEQVASIYTGTNGYLDSLEVLDVRPFLSGLRTYLTNNVPQYGEIVRKTNTFTPEAESLLKKAITDFLAEFGATKSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: AROG_HAEIN
Sequence: MAKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDRLLVVIGPCSIHDPKAAIEYATRLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYLNDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYLADFMSWGAIGARTTESQVHRELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIILRGGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFGSKQIFGVMVESHLVEGRQDLVDGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKATSN
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: ATX1_HUMAN
Sequence: MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
What is the function of this protein?
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor.  Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression.  Binds RNA in vitro.  May be involved in RNA metabolism (PubMed:21475249).  In concert with CIC and ATXN1L, involved in brain development (By similarity).
What are the official names of this protein?
Ataxin-1, Spinocerebellar ataxia type 1 protein.
What is the protein family that this protein belongs to?
Belongs to the ATXN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with USP7 in the nucleus.
Protein: LEU3_NITEU
Sequence: MKIALLAGDGIGPEIMAQAERVLRYFQQEGLQIELEPGLLGGCAVDATGEPFPEATRQLAIEADAILLGAVGGTQYDGLPREKRPEQGLLAIRKELNLFANLRPVVLYPELSNASTLKPEVVAGLDILIVRELTGDIYFGRPRGIEYRDGQKVGFNTMIYSESEIRRIAHVAFQAAGRRNGRLCSVDKMNVLECTQLWRDVVTETAQSYPDVTLSHMLVDNAAMQLVRNPRQFDVVVTGNMFGDILSDEASMLTGSIGMLPSASLDDRNKGLYEPIHGSAPDIAGKGIANPLATILSAAMMLRYSFNQETAASRIEHAVQKTLQQSYRTEDIYEAGMKKVGTVEMGDRVLANLQSR
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_NEIMA
Sequence: MPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNISNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHVGRKELFLEAGRMIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTHAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIRLVISDEELAARRAEMEARGSKAWKPENRDRYVSAALRAYGAMATSADKGAVRDVAQIER
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SPP1_ORYSJ
Sequence: MDKLSGSARLIIVSDLDHTMVDHHDEENLSLLRFGALWESVYCQDSLLVFSTGRSPTLYKELRKEKPMLTPDITIMSVGTEITYGEAMVPDDGWEEYLNNKWDRNVVVEETAKFSELKLQPETEQRPHKVSFFVDKKSAQEVIKSLSGNMEKCGLDVKIIYSGGQDLDILPQGAGKGQALAYLLKKLSSCGKPPNNTLVCGDSGNDAELFSIPGVHGVMVSNAQEELLQWYAENAKGNPKIIHATERCAAGIIEAIGHFKLGPSVSPRDVGFPYVKEDHIKPTDAVVKFYVLYEKWRRAEVPKSDSVVQYFKNITHANGVIIQPSGLECSLHASVDALSSCYGEKQGKKYRTWVDRLFVSQSGSDSWLVRFDLWEAEGDARLCCLTSLALNVKPETPAGFLITHVHKTWLKGYSSADEQSSKL
What is the function of this protein?
Catalyzes the final step of sucrose synthesis.
What are the official names of this protein?
Probable sucrose-phosphatase 1, OsSPP1.
What is the protein family that this protein belongs to?
Belongs to the sucrose phosphatase family.
Protein: NEPR1_HUMAN
Sequence: MNSLEQAEDLKAFERRLTEYIHCLQPATGRWRMLLIVVSVCTATGAWNWLIDPETQKVSFFTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ
What is the function of this protein?
Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2.  LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol.
What are the official names of this protein?
Nuclear envelope phosphatase-regulatory subunit 1, NEP1-R1, Transmembrane protein 188.
What is the protein family that this protein belongs to?
Belongs to the CNEP1R1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Note=Filamentous pattern in the cytoplasm.
Protein: VP44_BPAPS
Sequence: MRLIREDSIEKHLVSEVRKIGGIAYKFVSPGRRGVPDRLVALPNGKIIFVECKAPGEKPTPYQLREHARLFALGHQVIVLDSQDLSSILPAVN
What is the function of this protein?
Nuclease.
What are the official names of this protein?
Putative nuclease p44.
Protein: Y2358_VIBC1
Sequence: MPSFDIVSEIDTVELRNAVDNANRELSTRFDFRNVNASFELVEENVKVSAEGEFQLKQMRDILRSHLAKRNIDANAMDAKNPEATGKNWHQNIAFRQGIDTPTAKKLVKLIKDAKLKVQASIQGDKVRVTGKKRDDLQATIAAIREAEMGIPFQYNNFRD
What are the official names of this protein?
UPF0234 protein VIBHAR_02358.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ISPDF_HELPY
Sequence: MSLIRVNGEAFKLSLESLEEDPFETKETLETLIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKDLHKLTTSGDLKHFTLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: ARI5B_MOUSE
Sequence: MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVRCTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWAHSDFSKWRCGLRATPVKTEAFGRNGQKEALLRYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLSYPQYCRYRSMLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENESVCDEFAPNLKGRPRKKKTCPQRRDSFSGSKDPNNNCDGKVISKVKGEARSALTKPKNNHNNCKKTSNEEKPKLSIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNTQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDTSEVSSEQRKEEETLNHKSAPEPLPAPEVKGKPEGHKDLGARAPVSRADPEKANETDQGSNSEKEAEEMGDKGLAPLLPSPPLPPEKDSAPTPGAGKQPLASPSTQMDSKQEAKPCCFTESPEKDLQGAPFSSFSATKPPLTSQNEAEEEQLPATANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIAREDLCSGLSQGHHSQSSDHTAVSRPSVIQHVQSFKNKASEDRKSINDIFKHDKLSRSDAHRCGFSKHQLGSLADSYILKQETQEGKDKLLEKRAVSHAHVPSFLADFYSSPHLHSLYRHTEHHLHNEQSSKYAARDAYQESENGAFLSHKHPEKIHVNYLASLHLQDKKVAAAEASTDDQPTDLSLPKNPHKLTSKVLGLAHSTSGSQEIKGASQFQVVSNQSRDCHPKACRVSPMTMSGPKKYPESLARSGKPHQVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPAKEASGKEKASEQESEGNKGAYGGHSGAASEGHKLPLSTPIFPGLYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAGINPQAAFPSSQLSSVHPSTKL
What is the function of this protein?
Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development.  Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-337, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes.  The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver (By similarity).  Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes.  Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation.
What are the official names of this protein?
AT-rich interactive domain-containing protein 5B, ARID domain-containing protein 5B, Developmentally and sexually retarded with transient immune abnormalities protein, Desrt, MRF1-like, Modulator recognition factor protein 2, MRF-2.
What is the protein family that this protein belongs to?
Belongs to the ARID5B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T2BLA_BACSQ
Sequence: MERQLKSIAYAFVANDIDVYIPDGESNCIVVTKLVCKDCGQYWHTSLSECYFCGTLNFYLYECNSCGKKYSLTSSSKSCDTDGCNGKLIKRCSNPECISRTNEEIQRATDEQGGVFDLNSSFNVSLNHCVTCGSKENYYKTYRIYSYRTEVEPNIEALREFANNNKLNSDEDVIIIKHLVDNVIHYGYIPYSKLDETTEITTTFSRFSDLVSELFPVNVPPNVTE
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CCN(7)GG-3' and cleaves after N-7.
What are the official names of this protein?
Type II restriction enzyme BslI subunit alpha, R.BslIalpha, Endonuclease BslI subunit alpha, Type IIT restriction enzyme BslI subunit alpha, Type-2 restriction enzyme BslI subunit alpha.
Protein: MHBI_KLEPN
Sequence: MKLYSFFNXRA
What are the official names of this protein?
Maleylpyruvate isomerase.
Protein: Y3006_TERTT
Sequence: MQKLVKTWLKRSKRIRGVLLQFSKELFFEFNERGCQRSAAALTYMTLFALVPLMTVTYTMFSAIPAFDGVGDQLNGLIFHHFLPETGEEVSQYLSDFSSQARRLSGVGVVMLLVTAYLMLRNIETTFNSIWGVKQARSGLSGYLLYWAILSVGPILVAAAFLLSTYLLSVQIMLEDLDGLGVMQLVYRVVPWALTSAAFTLLFVAVPNCRVPFKFGAIGGVITAFAFEVVKAVFGYIVANSSFKLIYGAFAVVPLFLLWVNLLWTIILGGAVFVRTLAEHSYASRISRLSDMIVVLICLALFREKAALGESVSDRDCVRLGIGLVHWQRMRSLMVEHRWIAVTESGDYVLSRDLRRANIWEVASMVRMPVSEELSSLRENIAGRAPWFADFLERQSELRSHAESAFSVSLESLFAAEHEEEKPLTDQT
What are the official names of this protein?
UPF0761 membrane protein TERTU_3006.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROE_RHILO
Sequence: MVEATKKAFVTGHPIKHSRSPKIHGHWLAQHGIDGSYEAIDVAPQDFAEFIAALQANGFRGGNVTIPHKEAAFAVAQRRDQAAEEIGAVNTLWFEDGVLRGGNTDGHGFAANLDDCAPGWANTGPAVVLGAGGASRAVIQALKQRGFSDIRIVNRTLARAQELRDRFGAGVSAHGTAATDELLADAGLLVNTTALGMVGNEGLAADPALLPDHAIVTDLVYVPLETPLLAAARARGLKTVDGLGMLLNQAVPGFEHWFGVRPQVTAELRALIVADLVPKP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS14_BACSU
Sequence: MAKKSMIAKQQRTPKFKVQEYTRCERCGRPHSVIRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity).  The major S14 protein in the ribosome.  Required for binding of S2 and S3 to the 30S subunit and for association of the 30S with the 50S subunit.
What are the official names of this protein?
30S ribosomal protein S14, 30S ribosomal protein S14 type Z, 30S ribosomal protein S14-1, BS-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CYOE_COXBU
Sequence: MRTRTEIVSTTQTSATWRDYFQLCKPRVVLLMLLTAIVGMCLASPGIVSWRVFLFGNLGIALAASSAAAINHLLEHHLDKLMRRTYRRPIVQGKINRKNAAIFAAILCILSMIILIAFVNLLTALLTFITLIGYAGFYTLYLKHATPQNIVIGGLAGAAPPLLGWVAVTGHIDPPALILLLIIFLWTPPHFWALAIHRIDDYAKANIPMLPNTHGIIYTKINILLYTLLLTAISFLPFVIMTSGWIYFSSVCLLNLGFLYWAIRLLTSQRKEIPMRTFQYSIWYLMLLFTALLVDHYVYLALKLY
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSP_SALTY
Sequence: MTQTLSQLENRGAFIERHIGPDAAQQQEMLNAVGAESLNALTGQIVPKDIQLATPPQVGEAATEYAALAELKAIAGRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFDVIVDDAAKALDHQDVFGVLLQQVGTTGEIHDYSALITELKSRKVVVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEFKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRENVAQLFNVLLGDSHGLNIETLDKDVALDSRSIQQSMLRDDAILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYHQMISQLSDWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLDDLRAKAEQHAANLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQVAILNANYIASRLKDAYPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESEGKAELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISDYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.