PharMolix/UniProtQA huggingface dataset:
Protein: PSAC_CRUWA
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: DTD_ALKEH
Sequence: MIGLIQRVREARVEVDGVVVGRTGRGLLALIGVQRDDDEPQARRLLERILGYRVFPDEAGRMNRSVRDIGGGLLLVPQFTLAADTRKGMRASFAPAASPERGEALFHRLLGLARESGVPVEAGRFAADMQVHLINDGPVTFWLEARPSAA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN3_PIG
Sequence: MPTVISASMAPRTGASQVPRTMPQAAQGKGTEAGVGNPGGKYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYLDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNKRLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPRDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLKMGDLIARMVRNMDESRLRDSDLIPEGCSDDRPTRTIVPVQFETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDSWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFIYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSRTYINMREVSERFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVRKKKTKPIIFVSDRANSNKELGVDQESEEGQDKTSPDKQEKSPKPEPSNTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNRVVNKHKDLKTEGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKSWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKYMNIDFDSFICCFVRLEGMFRAFNAFDKDGDGIIKLNVLEWLQLTMYA
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.  Proteolytically cleaves CTBP1.  Mediates, with UTP25, the proteasome-independent degradation of p53/TP53.
What are the official names of this protein?
Calpain-3, Calcium-activated neutral proteinase 3, CANP 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3, New calpain 1, nCL-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: RBFA_BRUA2
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRSPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSG_SALEP
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNY
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: PMT7_YEAST
Sequence: MKDLRLQGPYRKYIPYNIFQQCGIGHLKTLDYIFAFLIVITNFTLIWKSHSSSFWNRPWDNNSEQELSQLIQFYLDKAFYIHELPPFTIQFYSIIRRLKIAENLRYVSLFLNSSTLGFLFLITRRINCSRLISATGLLILSNWETFRNEGTIISFDSLEWCLFSVVIYSFISISIAKLGTTNWFANVITLSISLGLAISSKFIGIVTWAFVILSFVRQFDRLISDVKVTTIQIIKFVILCLLFVLIIPGSIFIISYSNLLSNFKTDTPQFSKYMSTYFKSYLRGPQVQPSRLYYGSTITLRHLDSMVGYLASHDISYPSDVDEQLVALSFEEFAADNEWLIEHPTLNLSFSEVYHADQLIPVEFGQSIKLRHKSTGKLLRASTAKPPISEQDYDFQISCTKDSNYEGGMDERWDVLLIKDEINNDKKDNADDKYIKPLQSEIRFYNNGQRCGLLGHDLRLPEWGRFEQEVLCMEYPVIPRTTFLIDSVQLPVDFQVPMIEYYIGKISSSAEFNHTLSWSQFLYLFKEYIFKQYKYNYYIKYGKNKVTFEDAFAVEKWPITLDTDSPVWFNFAWYGSLLSMIIFMCVQCKRMISWNPWTTAEPSFSIKWEVYNEFGWECIVGWFLHFYIFTMSPHFNLGKKLYFQSFFFSVLCLLESLDCLAK
What is the function of this protein?
Probable protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity.  Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.
What are the official names of this protein?
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1689_STRPQ
Sequence: MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQSKLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQYQNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGLRDNDQIVAINGYKVNSWNDLTEAVNLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVAIMVVLMIAVTWNDIMRVFF
What are the official names of this protein?
Putative zinc metalloprotease SPs1691.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE2_BURMA
Sequence: MIPGELVIDDGEHTLNAGRHTIALVVANTGDRPVQVGSHYHFHEVNDALSFDRAAARGFRLNIAAGTAVRFEPGQTRTVELVELGGARAVYGFQGKVMGPL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_RICRS
Sequence: MIKLLYPEFWQKRNIIAYLLLPISLIYQFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKARNVSFVIVTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLINELKPDIIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPQILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFFATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNAILVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKKA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL9_GEODF
Sequence: MKVILKENLDNLGHIGDIVKVAPGYARNYLLPKGLALEATTKNAKALDHAKKHLEYKKNKVLEQARQFAARIEGIALTLSHQAGEEGKLFGAVTNMELAENLKAQGVEIDRKKIVLAEPIKQVGDFTAIIKIHPEVNATLKVTVTKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DER_SHESH
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETHMAEQSLAAIEEADVVLFLTDARAGLTAADQAICEHLRRREKTTFVVANKVDGIDADSACAEFWALGLGEVYQMAAAQGRGVTNMIEYALAPYAEALGLNRDGDEDEDEEEREYSEEEAEAEQKRLQDLPIKMAIIGKPNVGKSTLTNRILGEERVVVYDSPGTTRDSIYIPMERDGREYVMIDTAGVRRRSKVHETVEKFSVIKTLKAVEDCNVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWDGIDQDIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESVQEAYDSATRRVSTSMLTRIMQMAQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRFMMNYYRRSLKVMGTPIQIRFQDSANPFEGMNTKKLTVSQERRRKRMMTHIKDKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RS6_PSEAE
Sequence: MRHYEIVFLVHPDQSEQVGGMVERYTKAIEEDGGKIHRLEDWGRRQLAYAINNVHKAHYVLMNVECSAKALAELEDNFRYNDAVIRNLVMRRDEAVTEQSEMLKAEESRNERRERRERPNDNAEGADGDDNSDSDNADE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TYSY_BACAN
Sequence: MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHNNNIWNEWAFKSWVESDEYTGPDMIDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDEFSNKYGYLGDVYGKQWRAWKTTAGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRPM
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTRLEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1403_MYCTU
Sequence: MTVYTPTSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTSGIRRGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAAAAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCRRGGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGLFRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPECVATLDAEITELCREYLCDGVMQWEYLIFTARKC
What are the official names of this protein?
Uncharacterized protein Rv1403c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1405c.
Protein: RNZ_MYCBT
Sequence: MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVREAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: FTSH_ALKPO
Sequence: MNRIFRNTIFYLLIFLVIVGIVSVFNSDQTETENVSFNEFAERLENGQVQELSVKPERQVYLVRGQFNDQAEDEFFQTYALRSEQTAELLFNAEDPTGTPFNLEIEPADETSGWVQFFTGIIPFIIIFILFFFLLSQAQGGGSRVMNFGKSKAKMVNEDKKKAKFKDVAGADEEKQELVEVVEFLKDPRKFSAIGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRADILDPALLRPGRFDRQIQVNRPDVNGREEVLKVHARNKPLNDDVNLKTIATRTPGFSGADLENLLNEAALVAARHDHTKISMIHIEEAIDRVIAGPAKKSRVISPKEKKIVAWHEAGHTVVGVKLENADMVHKVTIVPRGMAGGYAVMLPKEDRYFMTQPELLDKIIGLLGGRVAEEVTFGEVSTGAHNDFQRATGIARKMVTEYGMSEKLGPMQFISGSGGQVFLGRDIQNEQNYSDAIAHEIDLEVQRIIKECYARCKQILLENKDSLDLVAKTLLDMETLDAEQIKSLVHEGKLPDDHHLNAHLEKEKASESDVKVNINSKKEETPQVEAEQPQEPNTDEPIEKDPSVEDNRSFEDDTNKKE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: CPD1_YEAST
Sequence: MAIALWYCPPQGSVAYETLQMLIFSFQTLFPDSPVFEPHVTVTSHLVCNSKDDVNKILTSCVAAIQSIRSHQTAKKGRKGQVSHAVAAPLVSFNGCSVGKQYFKKIVLECNKNKILYGVAQVMREMYVEIDPETRSSRAATWVHEEFHPHVSLLYSDIHPVSQASLRVVQQRIEDALDVQLVPREKRKGSGNADGSNEVQMRWDFDVSSSLSWNIPGTFKVVNCVGPVQEWEVLGRVDV
What is the function of this protein?
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
2',3'-cyclic-nucleotide 3'-phosphodiesterase, CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. CPD1 family.
Protein: Y2416_ARATH
Sequence: MEEITDGVNNMNLATDSQKKNRIQVSNTKKPLFFYVNLAKRYMQQYNDVELSALGMAIATVVTVTEILKNNGFAVEKKIMTSTVDIKDDARGRPVQKAKIEITLVKSEKFDELMAAANEEKEDAEAQVQN
What are the official names of this protein?
Uncharacterized protein At2g34160.
Protein: DHE2_CLODI
Sequence: MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSIPVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIPYGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVDEYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQGIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLNFPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVFAERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIKEEYNVTMREAAYMHSIKKVAEAMKLRGWY
What are the official names of this protein?
NAD-specific glutamate dehydrogenase, NAD-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: TAF1C_MOUSE
Sequence: MDFPGTLRPSLFKAGPLGMTDGPDLSFMCSWRDALTLPGSQPQNCKDPTLSFAKNLLWEPSTPGPLPLLMPPDPDPWDPGVTAQDFLFRGGHCYQYQSQAVLDVTEQLSRFLWDHGDIAFAPLGRLMLENFRLEGNRGYSKKMTIVSAKKLLQDLGGHQPWGCPWASLSRRLRRFSIVGGPVLSRSVSLLMGKLLHEELAMRWEQLLMDEAFTGGALAWLPGRTARAGQLVYPSGGALDKLYFQEVSVTSGGNPRILENPGHVQLRGPVRQVVTSTVQGETLLAVRSDYHCATWKIDKQGPPALLQVMQVEKGATGISLSPHLSGELAICSRSGAVCLWTPQAGLQTIYKDTETLAFRDPSPWRWADFTAHPRVLTVGDRTGVKMVDIQGPPGCGLLLFRAGAEAACQKGERVLLAQYLGQPGQTPPSLHLICTQFSIYLMDERLPLVPMLKWDHGLPSAPLLARLLPPASPGHPRPLLLGGQGGQLQLLHITGEGTSMPQLAGPPQSLPSITESLSAFPLLEPKKQQLLQERLEAPVIGLAAVPLCASAPGLLLFQLSAAGDVFYQHLRLLQASSPRKVPEQATAPSVDQVSTPSWTPQASARCSRWLEDLMELSPTRPLWVAPTFSHRRFLGHMERQKSQETMPQKLRAAMAKGQLLRPGDLSTLPRAEPPPAPQCSQQDELTERLTEAWEGRVTAWWRRHRGETSETQTQSKRPKRRTQLSSTFSSFTSYLDSPDASSAPRSQDLSTSEARLQSPRVPPSQELTQEVWGQGVKRERRQTLRDHTDKLPLKRDTPGPVATPPSQASSLQTMSFRQQTPVHSGSQPPQKKPRMGF
What is the function of this protein?
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription.  The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter.  SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.  Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.  Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3 (By similarity).
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit C, RNA polymerase I-specific TBP-associated factor 95 kDa, TAFI95, TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, Transcription initiation factor SL1/TIF-IB subunit C.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_ARGDE
Sequence: GVGFKAGVKDYRLTYYTPEYKTKDTDILAAFRMTPQPGVPAEERGAAVAAESSTGTWTTVQTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMLTSIVGNVFGFKALRALXXEDLRIPPAYSKTFIGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRPRNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DUS3L_MOUSE
Sequence: MAETAAESGGGGDSGVGACERGVAPIKAQYRTTKERFHEYLDGDKQEGACQEVPTGDPAEPGAKRIRLEDGQENGKTEVAIESRERQVPKRARGQNKSRPHVKPAHYDKDRLCPSFLQEPATPCAFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRCPFSMTCRFAGAHLGPEGQNLVQEEVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAEQALNRLTQSPMPTVVPETTVAMATPKQNSCHAQLDTVGGAGTPQSSPVPTCGPLTDEDVIRLRPCEKKRLDISGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNGVLDVPLTVKMRTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFGNGDILSFEDANCAMQTGVAGIMVARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWGSDTQGVERTRRFLLEWLSFLCRYVPVGLLERPPQRINERPPYYLGRDYLETLMASQQAADWIRISEMLLGPVPPGFVFLPKHKANAYK
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs).  Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs.  Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation.
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like, mRNA-dihydrouridine synthase DUS3L, tRNA-dihydrouridine synthase 3-like.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
Protein: RLME_LEGPA
Sequence: MNRTKSSKRWLQEHFDDVYVKKAQAEGYRSRAVYKLKEIDDKESLIKPGMTVVDLGAAPGGWTQYASEKMRGSGRLVALDILPMDALPNVEFILGDFREDNVLQELINLIPQRTLDLLLSDMAPNMSGSSAIDIPRAMYLVELAFDFAEKMLKPGGNMLVKIFHGSGFDELVKQARASFEKVVIRKPSASRSRSKETYLLAKGYNL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_SIBFO
Sequence: MNPHATPVLVLSLALGTTITISSNHWVLAWTGLEINTLAIIPLISKSHHPRAVEAATKYFLTQAAASALVLFSSMTNAWATGQWDITQLNHPTSCLLLTAAIAIKLGLVPFHFWFPEVLQGSPLMTALLLSTLMKFPPLTLLLMTSKSLNPALLTTMALASAALGGWMGLNQTQTRKILAFSSISHLGWIAIILVYNPKLALLTFYLYTIMTSAVFMALNKIKALNLSMILTSWTKTPVLNATLMLVLLSLAGLPPLTGFMPKWLIIQELTKQEMTPAAMAIAMLSLLSLFFYLRLAYHSTITLPPNSSNHMKQWYTSKPPSTPTAILASLSILLLPLSPMIHAIV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYE_TOBAC
Sequence: MATLAAAPWFRVRLIPELKNSQSLLYCRGNHSYRQSLCSRRRSFSVYASAGDGGDVRVRFAPSPTGNLHVGGARTALFNYLYARAKGGKFILRIEDTDLERSTKESEEAVLRDLSWLGPAWDEGPGIGGEYGPYRQSERNALYKQFAEKLLQSGHVYRCFCSNEELEKMKEIAKLKQLPPVYTGRWASATEEEVVEELAKGTPYTYRFRVPKEGSLKIDDLIRGEVSWNLDTLGDFVIMRSNGQPVYNFCVTVDDATMAISHVIRAEEHLPNTLRQALIYKALGFPMPHFAHVSLILAPDRSKLSKRHGATSVGQFRDMGYLPQAMVNYLALLGWGDGTENEFFTLEQLVEKFTIERVNKSGAIFDSTKLRWMNGQHLRSLPSEELNRIIGERWKDAGIATESQGIFIQDAVLLLKDGIDLITDSEKALSSLLSYPLYETLASAEGKPILEDGVSEVAKSLLAAYDSGELSGALAEGQPGWQKWAKNFGKLLKRKGKSLFMPLRVLLTGKLHGPDIGATTVLLYKAGTSGSVVPQAGFVTFDERFKILREVQWESFSTDVPLSAGAVTR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, chloroplastic/mitochondrial, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: ZAPB_SHEB2
Sequence: MSLELLSKLETKIQAALETIELLKMELEEEKQKASTLSEHNQQLNAQNQQLQEELTSWNEKVTGLVGLLNSEI
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.