PharMolix/UniProtQA huggingface dataset:
Protein: DER_CHLPD
Sequence: MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGYCPEGDVISMAMLEQTLMAIRDADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVNKVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDMLDSLPVQEKQLVEKDLPTNLAVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTKIDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDLVEKDSKTSAHYEKEVRSHMGNLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSALNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFFCNDPELLQTNFRKFLENKLREHFKLEGVTVSLRFFKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL7_PONAB
Sequence: MEGVEEKKKVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Binds to G-rich structures in 28S rRNA and in mRNAs.  Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SHEON
Sequence: MANTLEQLKSYTTIVADTGDIEAIKRYQPEDATTNPSLILKAAQIPEYSALIDNAIAWAKLQSTDIEQQIDDASDKLAVNIGVEILKLVPGRISTEVDARLSFDKEKSIAKAHKLVRLYQEAGVDKSRILIKLASTWEGICAAKELEQEGINCNLTLLFSFSQARACAEAGVYLISPFVGRILDWYKKDTGKDYDAVNDPGVVSVTEIYNYYKQHGYNTVVMGASFRNIGEIIELAGCDRLTIGPSLLEELANSQLAIQPKLVPTSTTVAVAEPLTEAQFRWEFNQDAMAVDKLAEGIRNFAIDQGKLEVMLKAKLAN
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LARP7_MACFA
Sequence: METESGNQKNVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNVQAKEENMDTTNTSISKMKRSRPTSEGSDIESTEPQKQSSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLGPRSKVKKIIQKDIIKEPSEASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMDLKKEYLALQKASMASLKKTISQIKSESEMETDGGVPQKTGMKNEKTNSEECPTQEKVNATGPQFVSGVIVKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEISKKHCWKLEILSGDHEQRYWQKILVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASKHIRFSEYD
What is the function of this protein?
RNA-binding protein that specifically binds distinct small nuclear RNA (snRNAs) and regulates their processing and function.  Specifically binds the 7SK snRNA (7SK RNA) and acts as a core component of the 7SK ribonucleoprotein (RNP) complex, thereby acting as a negative regulator of transcription elongation by RNA polymerase II.  The 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.  The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC).  LARP7 specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA; on stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex.  LARP7 also acts as a regulator of mRNA splicing fidelity by promoting U6 snRNA processing.  Specifically binds U6 snRNAs and associates with a subset of box C/D RNP complexes: promotes U6 snRNA 2'-O-methylation by facilitating U6 snRNA loading into box C/D RNP complexes.  U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity.  Binds U6 snRNAs with a 5'-CAGGG-3' sequence motif (By similarity).  U6 snRNA processing is required for spermatogenesis (By similarity).
What are the official names of this protein?
La-related protein 7, La ribonucleoprotein domain family member 7.
What is the protein family that this protein belongs to?
Belongs to the LARP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RS4_SYNC1
Sequence: MARYTGPVCRLCRRETMKLFLKGDRCYTDKCALERRNYAPGQHGQGRTKVSDYGTQLREKQRMKRTYGLLEKQFRAYFDKADSMKGVTGENLLVLLERRLDSAVYRLGFASSRTEGRALVRQGHFLVNGRKVNIPSYVMRPNDVIELREKSRKITRINDALDGVMRRGLPSWVELDREAFKGTFKTLPVREEMTTPAFQEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AMHX_BACSU
Sequence: MQKLSEEMKQTIMDIFEHLHANPEVSWKEYETTSFLKQKLEDLGCRTRTFSDCTGVVGEIGSGSPVVAVRADIDALWQEVNGTFRANHSCGHDSHMTMALGTLMLLKKQPELPKGTIRFIFQPAEEKGGGALKMIEEGVLDDIDYLYGVHVRPIQETQNGRCAPSILHGSSQHIEGTIIGEEAHGARPHLGKNSIEIAAFLVHKLGLIHIDPQIPHTVKMTKLQAGGESSNIIPGKASFSLDLRAQTNEAMEALIAETERACEAAAAAFGAKIELHKEHSLPAATQNKEAEAIMAEAITEIIGAERLDDPLVTTGGEDFHFYAVKVPNLKTTMLGLGCGLQPGLHHPHMTFDRNAMFTGIHILANAVLKTFQKAESLAAANAS
What are the official names of this protein?
Amidohydrolase AmhX, Aminoacylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: NEPI_ECOBW
Sequence: MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMKKS
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADDA_STRT2
Sequence: MLTKAFLSPAEIEERIAQEAASDKDRKLTPEQIEAIYSNGTNILVSASAGSGKTFVMVERILDMIGRGVGIDQLFISTFTVKAAGELKERLEKRLTKHLGQAETDEERAFLSDQIAKIGTADIGTMDAFTQKLVNQYGYLLGVSPTFRIMTDLAEQTLMKNEVYADLFNDYMQGKDAQLFQKLVRNFTGHSKTSKAFRDLVYDIYSFSQATADPEKWLCQNLLKGQIEAKPEQAKNELLDGLKDGLLADFLAFLRDHLGIAQREFAKAKYLNNVSDAIILLEGSLINDQTDMEDLLKQLLTLSGGTGLTNMTRPKDEELKAYKEAYNKTKNEFVAQLREVDTQLTVLEVLTKHNDDILPMLELLQSFVLDFSDQYLQAKIQENTFEFSDIAHFAIRILEENPEVAVSYRDRYHEVMVDEYQDNSHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKFQLFLENPDAGKLILLKENFRSQSEVLDATNGVFSHLMDQEIGDILYDKTHMLVAGSQKQKEPHPENETEVLIYNSDESSTSEDEEGPDQAISSGEISLVIKEIIKLHEQGVRFEDITLLAPNRNTYLDLMVSFEEHGIPLVPDEYKSSYLESLEVMIMLDTLRAINNPLNDYALVALLRSPMFNFNEDDLTRIAVQADKGQFYDKLLAAHTKSGLHPEVVMQGLEAKLTLFTETLADWRDYSKCHSIYDLIWKIYNDRFYYDYVGGLPRAEQRQANLYALALRANAYEKTGFKGLSRFIGMIDKIIASGNDLEEVTDLVPKNAVSLMTIHKSKGLEFKYVFVLQMNRKFIGHSKDGLSGKYIINREKGLGIKYLADLKDQINTNLPKLNVVLETLTFQENRREERRASISEEMRLLYVAMTRAEKKLYLVGKGSKETLTQQYGTDVENNRLPVALRDQIATYQDWIMALDTAFMRKDLKFTVRFVEDEELTPEAIGQVEVKAAVDADDLSNNRQTEEIERALTVLESVEKLNHLYAPAIDLPSVRTPSQLKTFYEPIMDTEGVDIMDKKEGVQPLETASTFELPDFGQKTKVTGAAVGSATHELMQRLTLSDTVTLQDLTQALSRVSASDQVKARVQLEKLLGFFDTELGKLILANRDKLRREAPFAMLAEDPASKEDFVVRGIIDGYLLLEDRIVLFDYKTDHFTHPSELKTRYQGQMSLYAKALSQAYQMEKVDKYLILLGGKDLEVVEV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: SOX3_XENTR
Sequence: MYSMLDTDLKSPVQQSNAPNGGPGTPGGKGNASIPDQERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGNLLAPGVSPVASSVGVGQRIDTYAHMNGWTNGAYSLMQDQLGYSQHPGMNSPQMQQIQHRYDMGGLQYSPMMSSAQTYMNAAASTYSMSPAYNQQSSTVMSLGSMGSVVKSEPSSPPPAITSHTQRACLGDLRDMISMYLPPGGDASDPSSLQSSRLHSVHQHYQSAAGPNGTVPLTHI
What is the function of this protein?
Transcription factor with sequence-specific DNA binding activity.  Binds to the consensus sequence 5'-[AT][AT]CAA[AT]G-3', showing a preference for 5'-AACAAT-3' and 5'-AACAAAG-3'.  Inhibits beta-catenin-mediated dorsal axis specification by binding to sites within the promoter of the beta-catenin-regulated gene nodal5.  Maternally derived sox3 acts as a transcriptional repressor of nodal5 and nodal6 to restrict their expression to the vegetal hemisphere of early embryos and thus establish germ layer formation.  Acts at multiple points to inhibit nodal signaling, repressing the expression of the other mesoderm-inducing nodal genes nodal, nodal2 and nodal4, and also acting downstream to induce expression of genes including trim33/ectodermin, ema and coco, whose products repress nodal signaling (By similarity).
What are the official names of this protein?
Transcription factor Sox-3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily cytoplasmic in early embryos. Nuclear localization becomes more pronounced as development proceeds (By similarity).
Protein: YCF52_PORPU
Sequence: MIFWKTFFQNSTVGESYENNFKKLFLLDKTFDKIELKDVYLSNTKNINLYELEQLCDSVGWVKRPLKKVKIALKHSSIIISLIQKNDSSTRLVGFARATSDNGFNATIWDVVIHPDFQGLGLGKVVMHQLIKQLRQAEISTITLFAEPDVISFYRKLGFIKDPDGVKGMFWYPR
What are the official names of this protein?
Uncharacterized N-acetyltransferase ycf52.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. Ycf52 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PP206_ARATH
Sequence: MKLYCNSNEVRSRTLATLRQLRQPSPATFLDTRRVDARIIKTGFDTDTCRSNFIVEDLLRRGQVSAARKVYDEMPHKNTVSTNTMISGHVKTGDVSSARDLFDAMPDRTVVTWTILMGWYARNSHFDEAFKLFRQMCRSSSCTLPDHVTFTTLLPGCNDAVPQNAVGQVHAFAVKLGFDTNPFLTVSNVLLKSYCEVRRLDLACVLFEEIPEKDSVTFNTLITGYEKDGLYTESIHLFLKMRQSGHQPSDFTFSGVLKAVVGLHDFALGQQLHALSVTTGFSRDASVGNQILDFYSKHDRVLETRMLFDEMPELDFVSYNVVISSYSQADQYEASLHFFREMQCMGFDRRNFPFATMLSIAANLSSLQMGRQLHCQALLATADSILHVGNSLVDMYAKCEMFEEAELIFKSLPQRTTVSWTALISGYVQKGLHGAGLKLFTKMRGSNLRADQSTFATVLKASASFASLLLGKQLHAFIIRSGNLENVFSGSGLVDMYAKCGSIKDAVQVFEEMPDRNAVSWNALISAHADNGDGEAAIGAFAKMIESGLQPDSVSILGVLTACSHCGFVEQGTEYFQAMSPIYGITPKKKHYACMLDLLGRNGRFAEAEKLMDEMPFEPDEIMWSSVLNACRIHKNQSLAERAAEKLFSMEKLRDAAAYVSMSNIYAAAGEWEKVRDVKKAMRERGIKKVPAYSWVEVNHKIHVFSSNDQTHPNGDEIVRKINELTAEIEREGYKPDTSSVVQDVDEQMKIESLKYHSERLAVAFALISTPEGCPIVVMKNLRACRDCHAAIKLISKIVKREITVRDTSRFHHFSEGVCSCGDYW
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At2g01510.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: RR3_CHAVU
Sequence: MGQKIHPLGFRLGFIQEHYSHWFAKANSYSELLQEDKEIRSCIYNHIRNHVRNSSNYGGIARINIYRRTDLVQLQIHTGFPALLIENRIRGLEHLRRDIQEKIDHKKRKLRMTLVEVLKPYTEPTILAEYIALQLENRVAFRRVMKKAIQLAKISDIKGIKIQIAGRLNGAEIARNEWIQKGRLPLQMLRANIHYCHYPAHTIYGVLGIKVWIFREKII
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YJV8_YEAST
Sequence: MGVLENIVPGELYDANYDPDLLKIRKETKIKLHEYNTLSPADENKKSQVIRELLGSCTDNFIIEPPFYCDYGSNIYIGDNFYANHNLVILDGAKVVIGDNVFIAPNVGIYTAGHPIDVERRLQGLEYAMPVTIGDNVWIGGGVSIIPGVNIGKNSVIAAGSVVIRDIPENVVAAGNPCKVIRKITEKDSTTTNYRK
What are the official names of this protein?
Putative acetyltransferase YJL218W.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: AL3A1_RAT
Sequence: MSSISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKERFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQKVAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVKSLLNEEAHKARYPPSPAKMPRH
What is the function of this protein?
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable).  They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable).  Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:2831537).  Preferentially oxidizes aromatic aldehyde substrates (PubMed:2831537).  Comprises about 50 percent of corneal epithelial soluble proteins (By similarity).  May play a role in preventing corneal damage caused by ultraviolet light (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase, dimeric NADP-preferring, Aldehyde dehydrogenase family 3 member A1, HTC-ALDH, Tumor-associated aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_MYCAP
Sequence: MNILKDLEERLILKDISNKDKFANLSPSTTGVYVGFDPTAESLHLGNYILISVLLRFKEYGFKTYAVLGGATGMIGDPSFKDSERVLLDNESVNKNKSKIKAQLESFGLEVIDNYDFYKDMNVLEFLRNVGKLVNVSYMMAKESVQKRIQKGLSFTEFTYQLLQGFDFLKTYQELGVKVQLGGSDQWGNIVTGIDMISKVVGDKHEAVGVTVNLLSDENGKKIGKSTGGGALWIDKNMCSPFKMYQYLLSQKDSRIKELLYWFSFKSVSEINEVLEKHFANPSTQEAQRFLASEVVENIFGANELKQAKNITKILFDKSFDASVLTLNDLEIIENYLPTCPIRQGDSVIETLIKNKFIVSNREAREFIQAKALKIDNKEIEFDSIYSPSLFEGKYAFFKKGKKQVILFKTV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGFZ_ECOBW
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO6_SULIA
Sequence: MGLERDGILSQDLHFNEVFVSLWQNKLTRYEIARVISARALQLAMGAPALIDINNISLTDVISIAEEEFKRGVLPITIRRRLPNGKIILLSLRKS
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMC8_HUMAN
Sequence: MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDHSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVAPTIHVYEHHENRWRCRDPHHDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176, PubMed:32439656).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231).  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
What are the official names of this protein?
ER membrane protein complex subunit 8, Neighbor of COX4, Protein FAM158B.
What is the protein family that this protein belongs to?
Belongs to the EMC8/EMC9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LSPA_BORAP
Sequence: MSVKSKQYFNIFIFIISLIFFDQLSKYLVVKYVKLGSVYFSFFENFFRIIHVRNTGILFSIGSNINYSLKKIFFLAMPIFILIFIFSLSLKEKNRIARISLLLIFSGGVGNVIDRLFRPSGVVDFLDFKFYGIFGLDRWPTFNFADSYVVIGMILFLVYDFFIKRKAFNT
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YDMD_SCHPO
Sequence: MKDYYSENGFEEIFEEKGSTSSNISDNCASRDYDVNISSDNPRLLDSYRPKGNYGRDRNSPLSRHIGVPNQEIILQGLTPEILEEHIELALYATGAKVSTVTLIREKETQKSRCFAFAKFVSLQDSKDWMEANFPTLVIDGIDVSVRFSRAAREQIEGWCCQNCDILNYSYRESCFKCRVPRNQASIAIGNHKISKRNGDMDVSDVPSVYLILRNLDRSLSEETLWKGLSKLEIDVQRVFMIRYKFNDAFCGYAILEFKDVDESAKALMKARTYPGKGFTLASRKVSVDYIHDGVLIPAYTESARWQFPTKTGYLVYWDPELYCSIYVPEGIDTDQFKPIEVNKKPKKEKRARSSNYIDVPASKKVATSLQRWNDAQKELKDNIPDLSEEEEKLLLHFVWKSALICVLCERKFQSWGHVVKHITQSIMHNNNLKNHELVSSAELLMHRVRQTESVDYRDRATERRIVPAASSDTIVEAKKSSQGSSFHSTSNVSMKMLNSMGWNKGSGLGTNENGIKEAIQPTMYLPGVGLGNKGSKIQINMTPVDRVKDRARSLYFQNDKNNNL
What are the official names of this protein?
Uncharacterized RNA-binding protein C57A7.13.
Protein: YTFE_SHISS
Sequence: MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARKELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVERVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEHDEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PROM1
Sequence: MSAKTDEILDSLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAAAGGDGADAAEEKTEFEVVLESFDASSKIKVLKEVRNATGLGLGEAKALVEAAPKTIKEGATKEDAEALKKAIEAVGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: LGT_DESVM
Sequence: MLAYPRIDPVAVSIGPLQFRWYGLMYLFGFISGWWLGRRRAAQPGSGWHPQQVDDMVTWAIFGVVLGGRLGYILFYDLAYYASQPAAIFQIWHGGMSFHGGLLGVLFAVWLYARRAEREFLSVVDFVAPLIPPGLFFGRIGNFINGELWGAPTTLPWAMVFPDGGPFPRHPSQLYEAVLEGVVLFAAVWWFSGRKRPVGAVSGLFGVLYAIFRFAVEFVREPDPQLGYLAFGWLTMGQVLCLPLFGVGMWLLLRNRGAAEGPAAR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MFNA_METMP
Sequence: MDEQDILNELREYRNQDLKYEEGYILGSMCTKPHPMARKISEMFFETNLGDPGLFKGTSKLEKEVVSMIGGILHNKNAFGYLISGGTEANLTAMRAFKNISKSKGKPQNIIIPETAHFSFDKAKDMMDLNVVRPPLTKYFTMDVKFIKDYIEDSKNEVSGIVGIAGCTELGSIDNICELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLDGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFRDNMFKKYLDVDAPYLTEKQQATIIGTRSGVGVASTWGIMKLLGIDGYETLVNESMEKTMYLVKKAREYGFETAIDPVMNIVALNDENKHDTCMKLRDENWYVSVCRCVDALRIVVMPHLEIEHIDGFLESLSNTKKY
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: PPR98_ARATH
Sequence: MSLAKRFVHLRKASPSFCLRGIYFSGLSYDGYREKLSRNALLHLKLDEAVDLFGEMVKSRPFPSIVEFSKLLSAIAKMKKFDLVISFGEKMEILGVSHNLYTYNIMINCLCRRSQLSFALAILGKMMKLGYGPSIVTLNSLLNGFCHGNRISEAVALVDQMVEMGYQPDTVTFTTLVHGLFQHNKASEAVALVERMVVKGCQPDLVTYGAVINGLCKRGEPDLALNLLNKMEKGKIEADVVIYSTVIDSLCKYRHVDDALNLFTEMDNKGIRPDVFTYSSLISCLCNYGRWSDASRLLSDMLERKINPNVVTFNSLIDAFAKEGKLIEAEKLFDEMIQRSIDPNIVTYNSLINGFCMHDRLDEAQQIFTLMVSKDCLPDVVTYNTLINGFCKAKKVVDGMELFRDMSRRGLVGNTVTYTTLIHGFFQASDCDNAQMVFKQMVSDGVHPNIMTYNTLLDGLCKNGKLEKAMVVFEYLQKSKMEPDIYTYNIMSEGMCKAGKVEDGWDLFCSLSLKGVKPDVIAYNTMISGFCKKGLKEEAYTLFIKMKEDGPLPDSGTYNTLIRAHLRDGDKAASAELIKEMRSCRFAGDASTYGLVTDMLHDGRLDKGFLEVLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g63080, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ASSY_ALISL
Sequence: MNKKVNVNKVVVAYSGGLDTSVIIPWLKENYDCEVIAFVADVGQGAEELEGIEAKAIASGASECYVADLKEEMVSEYIFPTLKTGALYEGKYLLGTSMARPIIAKAQVEVARNVGADALCHGCTGKGNDQIRFEGAFAALAPDLHVIAPWREWDLVSREECLDYLAERNIPCTASLTKIYSRDANAWHISTEGGVLEDTWNEPNEDCWAWTVDPEQAPNESETVSIKVEKGAVVAVDGKAMTPYEVVVYLNEKGIKHGVGRIDIVENRLVGMKSRGCYETPGGTIINEALRAVEQLVLDKASFEFREELGIKASHLVYDGRWFTPLCKSILAATEELAQDVNGDVVIKLYKGQATVTQKRSDNSLYSEEFATFGADEVYDQSHAEGFIRLYSLSSRIRALNSK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.