PharMolix/UniProtQA huggingface dataset:
Protein: SSN3_PHANO
Sequence: MERKRGREMNPPSADPPSATPVARANLPGSVAAAFHGRPCSQGTTTLKRVNERYKIVGFISSGTYGRVYKAEGKNGRTGEFAIKKFKPDKEGELQYSGISQSAIREMALCTELAHPNVVHTVEIILEEKCIFIVFEYAEHDLLQIIHHHNQPQRQAIPARTIKSILYQLLQGLVYLHRNWVMHRDLKPANIMVTSAGKVKIGDLGLARLFYKPLQSLFSGDKVVVTIWYRAPELLLGSRHYTPAVDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVEIMGMPSKDRWPLLTAMPEYPQLSSLIAGNAARFARPQGGDGLDRWYNQTLINNQYPAGPGPETPGAEGLALLKQLLEYDPQKRLTAEKALEHRYFTEHGKPSDNCFEDSKIKYPVRRVSQEDNDIRTSSLPGTKRSGLPDDSLMGRPAKRLKEG
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase SSN3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: END4_MYCBO
Sequence: MLIGSHVSPTDPLAAAEAEGADVVQIFLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRKILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPVYLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAAGAPVICETADQGRKDDIAFLRERTGS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PYRB_TRIEI
Sequence: MSTNIWTPRHILSLAEFTPTEYNIILQTATSFQEVLGRRMKKVPALQGQVVANLFFEPSTRTRNSFELAAKRLSADTLNFAPGTSSLTKGETILDTAMTYLAMGTDMMVIRHRNAGVPAAIASAMDRNGHQVRVLNAGDGQHEHPSQALLDLFTICKLLNSTEPRIELLETKKIAIVGDILHSRVARSNIWSLTASGAEVHLAGTPTLLPKYFGEFGKLRPSKLFVHWDIEPALEKADFVMTLRLQKERMSQHLLPSLREYHQLFGITRDRLKLCQPGVKILHPGPVNRGVEISSDLMDDPQLSLISQQVTSGIAVRMALLYLLGGGKADQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: HGLB_SCHJA
Sequence: MFYSIFFIHILRIVLVDCNEYSEENVDDRHKWAVLVAGSNGFENYRHQADVCHAYHVLLSKGVKPEHIITFMYDDIAHNKENPFPGKIFNDYRHKDYYKGVVIDYKGKKVNPKTFLQVLKGDKRAGGKVLKSGKNDDVFIYFTDHGAPGILAFPDDDLHAKPFINTLKYLRQHRRYSKLVIYVEACESGSMFAGLLPTDINIYATTAARPDESSYATFCDDPRISSCLADLYSYDWIVDSEKHQLTQRTLDQQYKEVKFETNLSHVQRYGDKKMGKLYLSEFQGSRKKASTEHDEPPMKPKDSIPSRDIPLHTLHRRIMMANNMNDKTLLMKILGLKLKRRDLIKDTMEVIDQFMFNVKQPNSNATIDETMDCIEVVYKEFQSKCFKIQQAPEITGYLSTLYNYCQKGYSAENINGVIRKVCG
What is the function of this protein?
This protease is used by the parasite for degradation of the host globin.
What are the official names of this protein?
Hemoglobinase, Antigen Sj32.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: RBL_AKABI
Sequence: TKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRMSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNAIIREASKWSPELAAACEIWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMH_UREU1
Sequence: MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEANRILKNINQNDFVIALIIEGKIISSEMLAENLQNWLNASYPNICFVIGGSNGLHEKIYERANYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VICA_HCMVM
Sequence: MDDLRDTLMAYGCIAIRAGDFNGLNDFLEQECGTRLHVAWPERCFIQLRSRSALGPFVGKMGTVCSQGAYVCCQEYLHPFGFVEGPGFMRYQLIVLIGQRGGIYCYDDLRDCIYELAPTMKDFLRHGFRHCDHFHTMRDYQRPMVQYDDYWNAVMLYRGDVESLSAEVTKRGYASYSIDDPFDECPDTHFAFWTHNTEVMKFKETSFSVVRAGGSIQTMELMIRTVPRITCYHQLLGALGHEVPERKEFLVRQYVLVDTFGVVYGYDPAMDAVYRLAEDVVMFTCVMGKKGHRNHRFSGRREAIVRLEKTPTCQHPKKTPDPMIMFDEDDDDELSLPRNVMTHEEAESRLYDAITENLMHCVKLVTTDSPLATHLWPQELQALCDSPALSLCTDDVEGVRQKLRARTGSLHHFELSYRFHDEDPETYMGFLWDIPSCDRCVRRRRFKVCDVGRRHIIPGAANGMPPLTPPHAYMNN
What is the function of this protein?
Plays a role in the inhibition of apoptosis by interacting with the pro-domain of pro-caspase-8/CASP8 and thus preventing its activation.
What are the official names of this protein?
Viral inhibitor of caspase-8-induced apoptosis, vICA.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: YIDE_SALDC
Sequence: MSDIALTVSVLALVAVVGLWIGNIKVRGVGFGIGGVLFGGIIVGHFVDQAGVTLSGDMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIMGGLVTAILHKIFAIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPVDLVDQMGMSYAMAYPFGICGILLTMWLMRLIFRVNVEAEAQKHESSLANGHSLIQTMNIRVENPNLNNMAIQDVPILNSDKIICSRLKRDDTLMVPSPGTIIQAGDLLHLVGQPTDLHNAQLVIGKEVDTSLSTRGTDLRVERVVVTNEKVLGKRIRDLHFKERYDVVISRLNRAGVELVASSDASLQFGDILNLVGRPASIDAVANVVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFVPGFPVALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLTQGEGLSWIGYGIFITEIPLITVGLLARIFAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVIFWGMG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVA_BORAP
Sequence: MINKIYGKVIEKKESSLVLMTAVFEFELLVSAFCLANFKLLDKVELFTYLYTKENELKLFGFLNSDERETFKSLIGVSGIGPRAALRVLSNIRYNEFKDAIDREDIELIAKIKGIGKKMAGKMFLHLQGKLLINNELESSLFRFKELEESIVSMGFDRKIVNSKLKEAFNLVEFSNLKDSEKEQFLFKEVLKRMSN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DTD_KOSOT
Sequence: MRAVVQRVSEAEVKVDGKIVGKISDGLMVLLGVQKDDTEKDLDWMLEKILNLRIFEDETGKMNLSLLEKGGQLMLVSQFTLLGDARKGRRPSFTEAAPPDKAKEIFDRFVKKASERVHVETGVFQAHMLVSLTNDGPVTILLDSRKQF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NART_STAHJ
Sequence: MYKTKGGFQLTLQTLSLVVGFMAWSIISPLMPYISQDVKVNPGQLSIILAIPVILGSILRVPFGYLTNIIGAKWVFFCSFVILLFPIFFLGQAQTPGMLMLSGFFLGVGGAIFSVGVTSVPKYFSKDKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIAIFAILMFIFGDKNEPKVKVPLASQFKKLSSNYKLYYLSLWYFITFGAFVAFGLFLPNYLVNNFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFIIMIVGAVILGISSHIALFTIGCLTISICAGLGNGLIFKLVPSYFAKESGAANGIVSMMGGLGGFFPPLVITYVTGLTGSSHLAFILLAIFGVLAFITMGHLYKKEYAK
What is the function of this protein?
Probably required for nitrate uptake under anoxic conditions.  Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
What are the official names of this protein?
Probable nitrate transporter NarT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRE_HAEIN
Sequence: MEQYKRDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGADLARLGEFYAAAIQASAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRKEVKDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANQAELAAVLIALNRKERGKGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSHLPEMRAYRAEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: BTUC_ECO8A
Sequence: MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFSPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADVVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSY_TRIV2
Sequence: MGLWLSLCGAVVVVAYLLGSFPTGYIAVKQLKGIDIREVGSGSTGATNVLRTLGKGPGAFVLGLDCLKGVLAIALVDYLFNFATSQNLIPTTVNVQLWQPWLVTLAGIAAILGHSKSIFLGFTGGKSVATSLGILLAMNWQVGLATFGVFAVVVAISRIVSLSSIMGAIAVSIVMVVLQQPLPYILFGIAGGLYVILRHRSNIERLLAGTEPKIGQKLTTETEQSA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHR2_ORYSJ
Sequence: MERISTNQLYNSGIPVTVPSPLPAIPATLDENIPRIPDGQNVPRERELRSTPMPPHQNQSTVAPLHGHFQSSTGSVGPLRSSQAIRFSSVSSNEQYTNANPYNSQPPSSGSSSTLNYGSQYGGFEPSLTDFPRDAGPTWCPDPVDGLLGYTDDVPAGNNLTENSSIAAGDELAKQSEWWNDFMNYDWKDIDNTACTETQPQVGPAAQSSVAVHQSAAQQSVSSQSGEPSAVAIPSPSGASNTSNSKTRMRWTPELHERFVDAVNLLGGSEKATPKGVLKLMKADNLTIYHVKSHLQKYRTARYRPELSEGSSEKKAASKEDIPSIDLKGGNFDLTEALRLQLELQKRLHEQLEIQRSLQLRIEEQGKCLQMMLEQQCIPGTDKAVDASTSAEGTKPSSDLPESSAVKDVPENSQNGIAKQTESGDR
What is the function of this protein?
Transcription factor involved in phosphate starvation signaling (PubMed:18263782, PubMed:26082401).  Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes (PubMed:25657119, PubMed:26082401).  Functionally redundant with PHR1 and PHR3 in regulating Pi starvation response and Pi homeostasis (PubMed:26082401).  Involved in both systematic and local Pi-signaling pathways (PubMed:19704822).  Regulates several Pi transporters (PubMed:18263782).  Regulates the expression of PT2 (PubMed:20149131).  Directly up-regulates SPX1 and SPX2 expression, but PHR2 binding to DNA is repressed redundantly by SPX1 and SPX2 in a PI-dependent manner (PubMed:25271318).  The DNA-binding activity is also repressed by SPX4 (PubMed:24692424).  Involved in root growth under Pi deprivation (PubMed:18263782).  Involved in the modulation of Pi response and homeostasis together with RLI1; promotes RLI1 expression in response to nitrate availability, thus triggering the nitrate-induced phosphate response (NIPR) (PubMed:33316467, PubMed:35640569).
What are the official names of this protein?
Protein PHOSPHATE STARVATION RESPONSE 2, OsPHR2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Interaction with SPX4 trap PHR2 within the cytoplasm and affects the nuclear localization.
Protein: HXD4A_DANRE
Sequence: MAMSSYMVNSKYVDPKFPPCEEYSQNSYIPEQSPGYYSPSQDTDFQHPGIYSRSNYSEQPYICSTVQGSSVQPRGHVQDQASTPSPFPAQTEQCPAVQISGSRTCGQQQNTKTQNGIPTKQPAVVYPWMKKVHVTTVNPDYTGPEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIESAHTLSLSERQIKIWFQNRRMKWKKDHKLPNTKGRSASVGNQHAQHAQKDSQTEITTL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D4a, Hox-D4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADRM1_CHICK
Sequence: MTTSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGFPTSSSSSSSRSQSAAVTPSSTTSSTHVTPAPAVPAAASVTSPSPVPSSGSGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQHGPLMSQFGLPAEAIDAANKGDVEAFAKAMQNSVKSDQKEGDSKDKKDEEEDMSLD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  Within the complex, functions as a proteasomal ubiquitin receptor.
What are the official names of this protein?
Proteasomal ubiquitin receptor ADRM1, Adhesion-regulating molecule 1, ARM-1.
What is the protein family that this protein belongs to?
Belongs to the ADRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NACB_CRYNB
Sequence: MDKEKLAKLQSQVRIGGKGTPRRKVVKKSVTSSQGDDRKLQAALKKLGVQPITGVEEVNMFKEDGNVLHFGAPRVQVHAALPSNTLAIYGPGQTKELTELVPGILNQLGPDSLANLRRLAESYQSLTARQAAAAAGSGGEGAGEAKEGEGDDEIPDLVDNFDEAEVKKSDLEELE
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
What are the official names of this protein?
Nascent polypeptide-associated complex subunit beta, NAC-beta, Beta-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: CALCB_RAT
Sequence: MDFWKFFPFLALSSMWVLCLASSLQAAPFRSALESSLDLGTLSDQEKHLLLAALIQDYEQKARKLEQEEQETEGSRKGSSSSVISQKRSCNTATCVTHRLAGLLRRSGGVVKDNFVPTNVGSKAFGRRRRDLRV
What is the function of this protein?
CGRP induces vasodilation.  It dilates a variety of vessels including the coronary, cerebral and systemic vasculature.  Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
What are the official names of this protein?
Calcitonin gene-related peptide 2, Beta-type CGRP, Calcitonin gene-related peptide II, CGRP-II.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBX2B_XENLA
Sequence: MSEAEPRETEAVTQPEPAPEIHKPDIVPPRNQINKKLLATQVQGTVKWFNVRNGYGFINRNDSKEDVFVHQTAIKKNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRFAPNRRRFRRQFYRPRADTAGESGGEGVSPEQMSEGEKGEETSPQQRPQRRRPPPFFYRRRFRRGPRPNNQQNQGAEVTDQSENKDPAAPTSEALASGDGQQRPPPRRFQQRFRRPFRPRPPPPQTPEGGDGEAKAEGEPQRQRNRPYVQRRRRQQPPTVQGESKAEPSEHPASEEGTPSDAPTDDGAPVETSEAGVEDTTAPE
What is the function of this protein?
Putative translation regulator.  May be involved in the developmental translational regulation of maternal mRNAs.
What are the official names of this protein?
Y-box-binding protein 2-B, Cytoplasmic RNA-binding protein p54, Frog Y-box protein 2-B, FRGY2b, Messenger ribonucleoprotein particle 3, mRNP3.
What are the subcellular locations of this protein?
Cytoplasm. Note=Either free or associated with ribonucleoprotein particles.
Protein: HXT7_YEAST
Sequence: MSQDAAIAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK
What is the function of this protein?
High-affinity glucose transporter.
What are the official names of this protein?
High-affinity hexose transporter HXT7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CF157_HUMAN
Sequence: MAPKKSVSKAGKELEVKKKGGKKEPVVAVEPPLAKEMKEFYHIQIRDLEDRLARYQRKWDELAVQEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEEVTDKFTLLEEQVRKQENEFRDYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTNRMWETTKRAIKENNGITLQMARVSQQGMKLLQENEQLKGRQNNLCKQLELLENTQKVMARHKRGHQKIILMLTKKCQEQQQDTKEAEELRLLLSQLEQRSLQLQVDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQKVRASLEAALVQATSFLQNILQMHRDEEDSDVDVTFQPWHKEMLQQLLVMLSSTVATRPQKAACPHQESQSHGPPKESRPSIQLPRTGSLLPQLSDITPYQPGDLGLVPRQVHIPPNPQDLRLLSYITRVGTFRAHSSPEMRAPGSLKRLEKFSLPEVPLRPK
What is the function of this protein?
Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility.  May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure.
What are the official names of this protein?
Cilia- and flagella-associated protein 157.
What is the protein family that this protein belongs to?
Belongs to the CFAP157 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: THIG_THEYD
Sequence: MNDSLVIRGIEFKSRLWVGTGKYKSFEETARAIEASGTDVVTVAVRRVNIIDRSKENLLDYIDPKKYKILPNTAGCYTVEDALRYARLAREAGVSDMVKLEVIGDEKTLFPDVCGLLKATEILAKEGFIVFPYTNDDPITAKRLVDAGAAAVMPLGAPIGSGLGIRNPYNIKIILETVNIPVIVDAGVGTASDVSIAMELGCDAVLVNTAIAGAKDPIMMAEALKHACIAGRLAYRAGRIPKKLYASASSPIEGMLT
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC1A_ARATH
Sequence: MSFSDSESSSHGGGGGDYKFFRQISRDRLLHEMLGSTKTGDSKAWKILIMDRVTVKVMSQSCKMADITDQGISLVEELFKRREPMPGMDAIYFIQPSKENIVMFLSDMSGREPLYRKAFIFFSSTIPKELVNHIKSDSSVLPRIGALREMNMEYFPIDNQGFLTDHEQALETLYAEDAENSRHFHICLNIMATRIATVFASLKELPFVRYRAAKSTASRDLVPSKLAAAIWDCISKYKAIPNFPQTETCELLIVDRSVDQIAPIIHEWTYDAMCHDLLDMEGNKHVIEVPSKTGGPPEKKEIVLEDHDPVWLELRHTHIADASERLHEKMTNFASKNKAAQMRSRDGSELSTRDLQKIVQALPQYGEQVDKLSTHVELAGKINRIIRDTGLRDLGQLEQDLVFGDAGAKDVINFLRTNQDTNPENKLRLLMIYATVYPEKFEGDKGVKLMQLARLSPVDMKVISNMQLIAGSPENKAKSGSFSLKFDAGKTKQANRKDRSGEEETWQLFRFYPMIEELLEKLVKGDLSKSDYLCMNQSSHKEESEARTGSVRKSSAPTAVPERKATPHSMRSRRTATWARPHSSDDGYSSDSVLKSASTEFKKLGQRIFVFIIGGATRSELRVCHKLTSSLRREVVLGSTSFDDPPQYITKLKLLSEKDIQGAPAQPFKPQYW
What is the function of this protein?
Involved in the vesicle trafficking.  Binds syntaxins (By similarity).
What are the official names of this protein?
Protein transport Sec1a, AtSec1a.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: HN_NDVU
Sequence: MDRAVSQVALENDEREAKNTWRLVFRIAILLLTVVTLAISAAALAYSMEASTPSDLIGIPTAISRAEEKITSALGSNQDVVDRIYKQVALESPLALLNTESTIMNAITSLSYQINGAANSSGCGAPIHDPDYIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHSHSHQYLALGVLRTSATGRVFFSTLHSINLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSAVPTSMVHGRLGFDGQYHEKDLDVTTLFEDWVANYPGVGGGSFIDNRVWFPVYGGLKPNSPSDTAQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRVQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRVLTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFDAFTRPGSVPCQASARCPNSCVTGVYTDPYPLVFYRNHTLRGVFGTMLDDKQARLNPVSAVFDSISRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGVREARAGRLSQLREGWKDDIVSPIFCDAKNQTEYRRELESYAASWP
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.