PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_ACIBY
Sequence: MTHFIFVTGGVVSSLGKGISAASVAALLEARGLKVTMVKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRRAKMTKLNNFTSGRVYQDVLNKERRGDYLGGTVQVIPHITDNIKERVLRAGEGYDVAIVEIGGTVGDIESLPFMESVRQLMVELGHKRTMLMHLTLLPYIKSAAELKTKPTQHSVKELLSIGIQPDILICRTEYDVDADTKRKIALFTNVEARAVVVCKDAKTIYQIPRGFYEQNVDDLICERFGFTDLPEADLTDWDNVVEALLNPEYTVRVAMVGKYVELPDAYKSVNEALLHAGIKNRVKVQIDYVNAEELESQDVSILKTADAILVPGGFGERGTEGKMKAIQYARENGIPFLGICLGMQLAVIEYARHVAGMPEASSTEFNRSTKYPLIGLITEWLDERGELQQRSLESDLGGTMRLGAQKSELVEGTKTREVYGKAEITERHRHRYEMNNRFIEAIEQAGMKISGYSSAQHLVETVEIPEHPWFIAVQFHPEFTSSPRDGHPLFASFIDAAKTQHQKSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y667_STAA3
Sequence: MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
What are the official names of this protein?
UPF0178 protein SAUSA300_0667.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SURF1_DICDI
Sequence: MNKNKKGFKLFFIFPVIAFGLGTWQVYRYDWKKRLIQRAKDRMEEDPIELSNSFIKNFKGSSFGDLNKYEFRRVYLNGKVIDNQYVLLGPRSIDGTLGYYVISPLQLSDGTRILLNRGWSASTPKSNYKIPYAIEELKLIHQKEKEQGQQQGNQESILYRYFNILGVISKTKERGSAFTPTNQPEKGQWYSLDVDAMADQLNTEPLMINTMDETEINSKPSSLPNPQFKRFDNDVESSFHNKHMSYIGTWYTLSASLFFIYFRYMRKLPK
What is the function of this protein?
Probably involved in the biogenesis of the COX complex.
What are the official names of this protein?
SURF1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRR_LIGS1
Sequence: MAKQIYDSMAMKRALTRMTYEIIEKNKGIDDLVLVGIKTRGVYLAQRIADRLKQLENAEVPVGQLDITLYRDDRHDASLAQDPVVNEADLGFDIKDKHVILVDDVLFTGRTIRAALDALMDIGRPKKINLAVLVDRGHRELPIRADFVGKNIPTAMDEQVAVYVDEVDGKDGIELKKL
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PGMC1_MAIZE
Sequence: MGLFTVTKKATTPFDGQKPGTSGLRKKVTVFQQPHYLQNFVQSTFNALPVDQVRGATIVVSGDGRYFSKDAVQIITKMAAANGVRRVWVGQNSLMSTPAVSAVIRERVGADGSKATGAFILTASHNPGGPKEDFGIKYNMGNGGPAPESVTDKIFSNTTTISEYLISEDLPDVDISVVGVTSFSGPEGPFDVDVFDSSVDYIKLMKTIFDFEAIKKLLTSPKFTFCYDALHGVAGAYAKHIFVEELGADESSLLNCVPKEDFGGGHPDPNLTYAKELVERMGLGKSSSNVEPPEFGAAADGDADRNMILGKRFFVTPSDSVAIIAANAVQSIPYFASGLKGVARSMPTSAALDVVAKNLNLKFFEVPTGWKFFGNLMDAGMCSICGEESFGTGSDHIREKDGIWAVLAWLSIIAFKNKDNLGGDKLVTVEDIVRQHWATYGRHYYTRYDYENVDAGAAKELMANLVSMQSSLSDVNKLVKEIRSDVSEVVAADEFEYKDPVDGSVSKHQGIRYLFGDGSRLVFRLSGTGSVGATIRVYIEQYERDSSKTGRDSQDALAPLVDVALKLSKMQEYTGRSAPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, cytoplasmic 1, PGM 1, Glucose phosphomutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCBB_ECOLI
Sequence: MLLNMMCGRQLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAVSEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARDMQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGYLHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYAAMHESLLALLCDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGDDTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGLGADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNGNQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESHGYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYLHDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNIRQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR
What is the function of this protein?
Responsible, at least in part, for generating a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link.
What are the official names of this protein?
Probable L,D-transpeptidase YcbB.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RECF_ECOSM
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE1_BACAN
Sequence: MELWFTEKQTKHFGITARINRTLHTEQTEFQKLDMVETEEFGNMLILDGMVMTTEKDEFVYHEMVAHVPLFTHPNPENVLVVGGGDGGVIREVLKHPSVKKATLVEIDGKVIEYSKQYLPSIAGALDNERVEVKVGDGFLHIAESENEYDVIMVDSTEPVGPAVNLFTKGFYAGISKALKEDGIFVAQTDNPWFTPELITTVFKDVKEIFPITRLYTANIPTYPSGLWTFTIGSKKHDPLEVSEERFHEIETKYYTKELHNAAFALPKFVGDLIK
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase 1, Putrescine aminopropyltransferase 1, PAPT 1, Spermidine synthase 1, SPDS 1, SPDSY 1.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACC_DICDI
Sequence: MESKDQNVYRKGSDNFSKGSNTFFGNLKSISTTTTTTTTTANTDQQVSKVAENNEIDDNSSVDSSSSNPSSSSTSTTPVKPKTFVDGALRGVWSIGVGVVNGAKGIVEQPYLGAKNNGLGGFVKGVAKGVSGVVILPAVGVLEFFSYTTQGIYNTPITVLDAMKSSPKEEEMITVSAEIPTIFFAVELEESFKTAKEKGIPHLLKVCIEFISRRKNIEGIFRISGSKFLIDEIQSKFDKGLITSVEDLDPNWIYEVACIFKSYFRYLPHSVIPDEQITEFYRIQNNITDATEKAAALKAVVNSIPNFQYTILYECISLLHDISLNSKENLMTPSNLSIVYGPSLLRPNIEKGDIQEIANANTIVFNLISFFQQIFIKNPDPSILEIEHPITPIKPMIQK
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacC, GTPase activating factor for raC protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3021_ACIF2
Sequence: MAERDFIIVSGLSGSGKSTVLQALEDQGYYCVDNLPATLLVDFGAQLARRDASSMLAAVSIDVRNREFLAALPQALADLRQRYALCPRILFLEADEGTLLRRFSETRRRHPLTDDLAAALGESLLTVLRREREMVQPLADVADKRLDTSQINTHQLRLRVQAWSLASRHYSGLVLLLQSFAFKKGLPLDSDFVFDLRALPNPHYDPELRALTGRDAPVRDFLEKSPEVARSFVSLRTFLQTWLAPFAQEHRNYVTVSLGCTGGQHRSVYMVEALARLLAGEGQRVLIQHRELGITETLT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein AFE_3021.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LPOA_ALIF1
Sequence: MANMTPRKNSVTRLIAPVALALTLAACSSSPKAPDRLDITQSPTETSNAYILKADQQQGALEADFLIMALKAAVQEQNFDLADKLFTRLATMQLSPAQTAEMQLAHAKMLKSQSQYEDALKTLNFEAWWKLENSQWVEYHKLRHELYLLSGDNLNSARELIELEPFTAEDQKAQLWTQVWTSVSSLNSTALEEVKLDETETNLHGWVQLATYLDTLKHSPMRLQETLNEWLLANPTHPAATYTPQVILDILALEIVRPENVALLLPLSGRFGPQGIRVRDGFINAMMEDKERDEFTKLKVIDTQATSMAEIMTTLEKEQIQFVVGPLVRSKIEEFQSLNSTEIAQLALNIPSEIDTDINSCYFTLSPEQEAEQAAVHLFKQGFKHPLYLAPQGTMGERLSQAFSDKWFQLTAKRPSISYFGSKAQLQQKVNSVFGIESSQARIYQMNALASMELEAQPRSRRDIDAVYMVAKSSELVLLKPFIEVAINPGIKPPKLYASSRSNSGRQTQLVEIKGIEFSDIPLLTNENHSFKAQYDELWPKSSNGETRLHALGMDAYQLVAELPQMKAVDNYRMEGKTGELSLNQECVIQRKMSWAVHGEETE
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: MINE_HERA2
Sequence: MGLLDNLFGRKQQNSSSVAKERLLTVLVHDRVHLTPHDMEEMKREIIAVIERYVEVTNPEAIEVTLTRGEAADHLKADIPLGRSRQQ
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: QUEA_RUEPO
Sequence: MKLSDFDFDLPDDLIATRPAQPRSSARLLVARGDAISDAVVRDLPDWLRPGDRLVLNDTRVIPARLSGTRQRQSAQGPVTARIEITLLEPRADGSWSALAKPLRKLREGETIIFSNDLSADVEAIEDGQALLRFNLTGPDFDAALAQAGAMPLPPYIAAKRAADEQDKTDYQTVWARHSGAVAAPTASLHFDDTLLAALAAHGVTFTHVTLHVGAGTFLPVKVEDVTTHKMHAEWGRVSAEAAAEIAATKAAGGRVIPVGTTALRLIESAARGGQIAPWEGDTDIFIYPGFDFRVADGLMTNFHLPKSTLLMLVSALMGQESIRKIYAHAVENRYRFFSYGDASLLLPG
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADR_VIBCH
Sequence: MVIKAKSPAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQMKMTLPSNFTEDDC
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_ASHGO
Sequence: MAGLKDVVTREYTINLHKRLHGVTFKKRAPRAVKEIKKFAKLHMGTEDVRLDPRLNTEIWKRGVKGVPFRMRLRISRRRNEEDNAKNPLFSYVEPVVVASAKGLHTVVVEEEEA
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: RAD52_ASHGO
Sequence: MADDKKGQMGNVDDIQAKLDKRLGPEYISKRVGHGTTRVAYIEGWKAINLANQIFGFNGWSSEVKSVTVDFMDERQGRFTIGCTAVVRVTLSDGTFREDIGYGTVENDRRKSGAFERAKKSAVTDALKRSLRGFGNALGNCLYDKDFLSKIDKVKFEPPDFDEGNLFRATDENNELSRANTVTDHSEGPAPKKRNAPLPPAPRPGAMRPEAAHAAPAPSEPPLERPRSSENDQEDLLDDSFMFSDELQDDDLINIGSAKKAPSGVPRPAPPPPPRAWPPQDAPVAFVTAKAAPDLQAHGPVPPTHLFDPKFQAQSIRHTVDQTTSAHVKLSVLREKGIDQARDDIYSKFAPKGKILPPPDTATDPDPTLAARPALSAPQNLPTNTSSIQRPTMIELPKLHFPQPTAVPLPNVPASRREVGRPKQSPPSLRKPPPQ
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair and recombination.  Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RAD52.
What is the protein family that this protein belongs to?
Belongs to the RAD52 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T4G1J_AGEOR
Sequence: MRTIISLLLLSAMVFAVIEAISLEEGLQLFEGERGCVGENQQCADWARPHCCSGYYCTCRYFPKCICRKDSGK
What is the function of this protein?
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects.  Modifies presynaptic voltage-gated sodium channels (Nav), causing them to open at the normal resting potential of the nerve.  This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons (By similarity).
What are the official names of this protein?
U3-agatoxin-Ao1j, U3-AGTX-Ao1j, Mu-2Aaga_11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 03 (aga-4) subfamily. Aga sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_SHIBS
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: THT2_MYCTU
Sequence: MPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAFRDDVLAILGAQPLIDVRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV
What are the official names of this protein?
Putative thiosulfate sulfurtransferase SseA.
Protein: NUOCD_YERPS
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHRQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YCF3_CHLVU
Sequence: MPRSQRNDNFIDKTFTVIADILLKILPTSNKEKQAFSYYRDGMSAQSEGEYAEALQNYYEALRLETDAYDRSYILYNIGLIHTSNGDHARALDYYYQALERNPSLPQALNNIAVIYHYRGEQALESSQTEISKLLFDKAADYWREAIRLAPTNYIEAQNWLKMTGRF
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSAB_BARVE
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFETWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSALSLIGGWLHLQPKWKPRVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGESVRWNNFLNVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGSGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAILFLIAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTSGPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ANGL6_MOUSE
Sequence: MGTARLRKLQLLLLLGAWRALGGAARCRVTLVLSPQKATSAVCRSSEATQDSELATLRMRLGRHEELLRALQRRAAEGGALADEVRALREHSLTLNTRLGQLRAQLQQEARAEPDLGAEPAAALGLLAERALDAEAEARRTTARLQQLDAQLREHAQLMSQHSSLLGRLQRACAGPERGQQQVLPLPLAPLVPLSLVGSASNTSRRLDQTPEHQREQSLRQQGPPSSLLPTGHLAVPTRPVGPWRDCAEAHGAGHWQSGVYDLRLGRRVVAVWCEQQQEGGGWTVIQRRQDGSVNFFTNWQHYKAGFGRPEGEYWLGLEPVHQVTSRGDHELLILLEDWGGRAARAHYDSFSLEPESDHYRLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYHRGGWWYHACAHSNLNGVWYHGGHYRSRYQDGVYWAEFRGGAYSLKKAVMLTRLVRL
What is the function of this protein?
May play a role in the wound healing process.  May promote epidermal proliferation, remodeling and regeneration.  May promote the chemotactic activity of endothelial cells and induce neovascularization.  May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
What are the official names of this protein?
Angiopoietin-related protein 6, Angiopoietin-like protein 6, Angiopoietin-related growth factor.
What are the subcellular locations of this protein?
Secreted.
Protein: WDFY1_MOUSE
Sequence: MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLAAEWVISTGHDKCVSWMCTRSGNMLGRHFFSSWASCLQYDLDTQHAFVGDYSGQITLLKLEQNTCSVITTLKGHEGSIACLWWDPIQRLLFSGASDNSVIMWDIGGRKGRTLLLQGHHDRVQSLCYLQLTRQLVSCSADGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLATFHEGKHNISHMSMDIARGLMVTCGTDRVVKIWDMTPVVGCSLATGFSPH
What is the function of this protein?
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1.  Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436).
What are the official names of this protein?
WD repeat and FYVE domain-containing protein 1, WD40- and FYVE domain-containing protein 1.
What are the subcellular locations of this protein?
Early endosome.
Protein: HEMH_FRATT
Sequence: MQQYSCKYNKQAILLVNLGTPDNYDTKSIKRYLKEFLSDPRVIEANPVLWKIILNLIILPIRAKKNVHTYKTVWNKQHNKSPLLFYTENLADKLDKKLDNYIVDYAMRYGNPSIESKIKSLQDQGATEIIIFPLYPQYSATTTATVYDEVYRVLSKLRWQPTIKGINPYYDNKFHIQTISQQIKEHLKKLDSTPDTVLFSFHGLPKEYFDKGDPYYCHCYKTYRLVKEELQNEYPNIDFELSFQSRFGPKKWLEPYTTVKLEEFTKQNKSVVVIAPGFSADCLETLEELAISEKENFIKKGGKEFSLIPCLNDSNQHVDMLYNIIDEEICLKK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TULP3_HUMAN
Sequence: MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFDSKLACE
What is the function of this protein?
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling.  Binds to phosphorylated inositide (phosphoinositide) lipids.  Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking.  During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
What are the official names of this protein?
Tubby-related protein 3, Tubby-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted. Note=Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha.
Protein: CPVL_PONAB
Sequence: MVGTMWKVIVSLVLLMPGSCDGLFRSLYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGRELSLVSPFLGLNMRSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGFSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVAQDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLKGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFQAFEILDKLLDGDLTSDPSYFQNVTGCSNYCNFLRCTEPEDQLYYAKFLSLPEVRQAIHVGNRTFNDGTTVEKYLREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTEHSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYVRQVGDFHQVIIRGGGHILPYIQPLRAFDMINRFIYGKGWDPYVG
What is the function of this protein?
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
What are the official names of this protein?
Probable serine carboxypeptidase CPVL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.