PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_DINSH
Sequence: MAQTVLGQKRFRKYYGKIREVLEMPNLIEVQKSSYDLFLKSGDQPQPMDGEGIMGVFQSVFPIKDFNETAVLEFVKYELEKPKYDVEECQQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDLVFARIDRRRKLPVTTLLYSLGMDQQDIMDAYYDTVTYTHRKGEGWVTKFFPERIRGTRPTQDVVDAATGEVIAEAGKKVTPRAVKQLIDEGNVSEILVPFDGIIGKFAAKDIINEENGAIYVEAGDELTWEVDKDGAVTGGTLKELLDAGIEEIPVLDIDNITVGAYMRNTLAADKNMNRDTALMDIYRVMRPGEPPTVEAASALFDTLFFDSERYDLSAVGRVKMNMRLALDAEDTVRTLRKEDIVSCIKALVDLRDGRGDIDDIDHLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRRVEDGKVTDEVNYMSATEEMRHTVAQANANLDESGSFVNEMVNTRQSGEYTLAPRESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLQADAPFVGTGIEGVVARDSGAAIMARRGGFIDQVDATRIVIRATEDLEPGDPGVDIYRLRKFQRSNQNTCINQRPLVKVGDKVGKDDVIADGPSTDLGELALGKNVVVAFMPWNGYNYEDSILISERVARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEALRNLDEAGIVYIGADVGPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRLPPGDFGTVVEVRVFNRHGVEKDERALQIEREEVESLARDRDDEMAILERNIYARLKDMILGKTAVKGPKGVKPGSEITEDLLGTLSRGQWWQLALEDEAEAQMVEALNQQYEAQKRALTARFEDKVEKVRRGDDLPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVISKVVPMEDMPFLADGTPVDFVLNPLGVPSRMNVGQILETHMGWAARGMGLKIDEALGEYRRSGDMTPVREAMRLAYGDEAYEEAISGLDQDDLLERAGNVTRGVPIATPVFDGAKEADVNDALTRAGFDTSGQSDLYDGRTGEKFARQVTVGVKYLLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVKEVRGLGLNMELLDAEGEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: POL_MMTVC
Sequence: MGVSGSKGQKLFVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKKYAAEHGTDSIPKQAYPIWLQLREILTEQSDLVLLSAEAKSVTEEELEEGLTGLLSASSQEKTYGTRGTAYAEIDTEVDKLSEHIYDEPYEEKEKADKNEEKDHVRKVKKIVQRKENSEHKRKEKDQKAFLATDWNNDDLSPEDWDDLEEQAAHYHDDDELILPVKRKVDKKKPLALRRKPLPPVGFAGAMAEAREKGDLTFTFPVVFMGESDDDDTPVWEPLPLKTLKELQSAVRTMGPSAPYTLQVVDMVASQWLTPSDWHQTARATLSPGDYVLWRTEYEEKSKETVQKTAGKRKGKVSLDMLLGTGQFLSPSSQIKLSKDVLKDVTTNAVLAWRAIPPPGVKKTVLAGLKQGNEESYETFISRLEEAVYRMMPRGEGSDILIKQLAWENANSLCQDLIRPMRKTGTMQDYIRACLDASPAVVQGMAYAAAMRGQKYSTFVKQTYGGGKGGQGSEGPVCFSCGKTGHIKRDCKEEKGSKRAPPGLCPRCKKGYHWKSECKSKFDKDGNPLPPLETNAENSKNLVKGQSPSPTQKGDKGKDSGLNPEAPPFTIHDLPRGTPGSAGLDLSSQKDLILSLEDGVSLVPTLVKGTLPEGTTGLIIGRSSNYKKGLEVLPGVIDSDFQGEIKVMVKAAKNAVIIHKGERIAQLLLLPYLKLPNPIIKEERGSEGFGSTSHVHWVQEISDSRPMLHISLNGRRFLGLLDTGADKTCIAGRDWPANWPIHQTESSLQGLGMACGVARSSQPLRWQHEDKSGIIHPFVIPTLPFTLWGRDIMKEIKVRLMTDSPDDSQDLMIGAIESNLFADQISWKSDQPVWLNQWPLKQEKLQALQQLVTEQLQLGHLEESNSPWNTPVFVIKKKSGKWRLLQDLRAVNATMHDMGALQPGLPSPVAVPKGWEIIIIDLQDCFFNIKLHPEDCKRFAFSVPSPNFKRPYQRFQWKVLPQGMKNSPTLCQKFVDKAILTVRDKYQDSYIVHYMDDILLAHPSRSIVDEILTSMIQALNKHGLVVSTEKIQKYDNLKYLGTHIQGDAVSYQKLQIRTDKLRTLNDFQKLLGNINWIRPFLKLTTGELKPLFEILNGDSNPISIRKLTPEACKALQLVNERLSIARVKRLDLSRPWSLCILKTEYTPTACLWQNGVLEWIHLPHISPKVITPYDIFCTQLIIKGRHRSKELFSKDPDYIVVPYTKVQFDLLLQEKEDWPISLLGFLGEVHFHLPKDPLLTFTLQTAIIFPHMTSTTPLEKGIVIFTDGSANGRSVTYIQGREPIIKENTQNTAQQAEIVAVITAFEEVSQSFNLYTDSKYVTGLFPEIETATLSPRTKIYTELRHLQRLIHKRQEKFYIGHIRGHTGLPGPLAQGNAYADSLTRILTALESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPDWGHAPQLGVNPRGLKPRVLWQMDVTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATKDVLQHLAQSFAYMGFPQKIKTDNAPAYVSRSIQEFLARWKISHVTGIPYNPQGQAIVERTHQNIKAQLNKLQKAGKYYTPHHLLAHALFVLNHVNMDNQGHTAAERHWGPISADPKPMVMWKDLLAGSWKGPDVLITAGRGYACVFPQDAETPIWVPDRFIRPFTERKEATPTPGTAEKTPPRDEKDQQKSPEDESSPHQREDGLATSAGVNLRSGGGS
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pro-Pol polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p10]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein-dUTPase]: Virion.
Protein: DNAE2_BRUAB
Sequence: MVPYFEMAAASNFSFLCGASHPQELVERAHALDLSGIGIADRNTLAGVVRAHAQWKDIRKESGFRLFIGCRLSFIDGTPDMVVYPRDRAAYGQLCRLLTEGKHRAAIKGECHLEWADLLFRARQFQIAVFPPDEDEPDFAARLTEIAQAAPGSVWLALTMPHQGQDGRRAERIARFAAQAGVPLIATNDVLYHHPDRRPLQDVLTATRHHTTVFAAGRLLEKNAERHLKPPHEMVRLFRDYPEAIAATADFVAPITFQLDELKYAYPDEPIPPGKTAQQHLYDLVWEGAARHYGADMIPPKVQGLINKELALIARLEYEPYFLTVYDIVTHAREKGILCQGRGSAANSVVCFCLGITGVNPTQVDLLFERFISAERKEPPDIDVDFEHERREEVMQYVYDRYSRDRAAIVATVISYRSRSAIRDVGKALGLSEDVTAALANTVWGLSGGGIDRQHIRQAGLDPDNPIIQRAVELAITLIGFPRHLSQHVGGFVLTRDRLDETVPIGPAAMDKRSFIEWDKDDIDEVGLMKVDVLSLGMLTCIRKAFDLIHQHKPQLYGGEKLTLASLPRKDKAVYDMLCKGDSLGVFQVESRAQMNMLPRLRPQEFYDLVIEVAIVRPGPIQGDMVHPYLRRRSGQEPCTLPSPSPQHGPANELQQILGKTKGVPLFQEQAMRIAMEAAKFTPEEANQLRRAMATFRKMGTIHTMEKKMIDGMVNRGYDRTFAENCFNQIKGFGEYGFPESHAASFAHLVYISAWLKCHHPEVFAAALLNSQPMGFYAPAQIVRDAREHGVTVLPVDVNFSQWDNILEETPDVHLALRLGFRQIDGFSKRDTELLIADRQEPYRTIEDMHRRLRLDRRAFTLLADADAFGSLDIDRRAALWAVRRLPNDETLPLFRAAAASELAQEPRTKLPEMAASEHVIADYETTRLSLKGHPLQYLREGLAAEGVSTCRAVQEGADGRRMKVAGVVTVRQRPGSAKGVVFLTIEDETGIANIVIWPKIMKVFRREVMSARLIHIEGRIQRSLEGVVHLVAAKLQDRSAALIEMSGREAQRLIAPSQMAHHPRNVRVMPNSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_PSECP
Sequence: MAAHCQVTGAEPGFGHSISHSHRRNKRRFDPNIQKKRYWVPSLRRNVTLQVSARGIKTIDVRGIDAVVASILARGVKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RS4_VIBVY
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGVHGARRGRLSEYGVQLREKQKVRRMYGVLEKQFRNYYAEAARLKGNTGENLLQLLEGRLDNVVYRMGFGATRAEARQLVSHKAILVNGKVVNVPSFKVAANDVVSIREKAKQQTRIKAALEVAEQREKPTWIEVDAGKMEGTFKRMPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MSCL_DEHMB
Sequence: MFKEFKIFIMRGNVVDLAVGIVIGAAFGAIVNSLVKDVLMPPIGLLLGNVDFGNLFIVLKEGAIGGPYESLLVAQTAGAVTINYGVFINALINFLILAMAIFFFVVRPLNQLAARQKSKEAVIPAQTDKKDCPYCATQIPLKASKCPYCTSELM
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOC1_LOTJA
Sequence: MIDQYKHQQLRIGSVSPQQISAWATKILPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICTCGNYRVIGDKKDEPKFCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPVVKKPTFLRLRGLFEYEIQSWKYSIPLFFATHGFDTFRNREISSGAGAIREQLVDLDLRIVIDSSLVEWKELGEERSTHNENEWEDRKVGRRKNFLVRRMELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLIDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMKDGHNKVYKSFSDIIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFLIRSLIRKHFASNIGVAKSKIREKEPIVWEILQEVMRGHPILLNRAPTLHRLGIQAFQPILVEGRAICLHPLVCKGFNADFDGDQMAIHVPLSLEAQAEARLLMFSHTNLLSPAIGDPIAVPTQDMLIGLYILTSGNRRGICANRYNRSNWKNSKNEKIRDKKYMKKKEPFFSNSYDAIGAFRQKKINFDSPFWLRWRLDKCIMSSREAPIEVHYESLGTYHDIYEHYLVIRSIKKQICCIYIRTTIGHISFYREIEEAIQGFCRGYSYGI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YLL53_YEAS7
Sequence: MWFPQIIAGMAAGGAASAMTPGKVLFTNALGLGCSRSRGLFLEMFGTAVLCFTVLMTAVEKRETNFMAALPIGISLFMAHMALTGYTGTGVNPARSLGAAVAARYFPHYHWIYWISPLLGAFLAWSVWQLLQILDYTTYVNAEKAAGQKKED
What are the official names of this protein?
Putative uncharacterized protein SCY_3531.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YAE1_YEAS7
Sequence: MSNTWDDVWASDSDVETERSPDLLKLRENHSKRGYLDGIVSSKEEKLQEGFNDGFPTGAKLGKQVGIIMGILLGLRTRFGDEDEGLSKAYIDAQKELRINKVLSKSIFDPNFDLQEKHPLITKWTDIVNTYCEKYHVPSIQ
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein YAE1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CO4_CAVPO
Sequence: KPRLLLFXPXVVVLXVPLXVXV
What is the function of this protein?
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway.  Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes (By similarity).
What are the official names of this protein?
Complement C4.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_CLOBK
Sequence: MARISGIDLPKEKRVEIGLTYIYGIGLPTSQEILKATGVNPDTRVKDLSEEEVNAIRDYVNKNVKVEGDLRREIKLNIKRLVEIGSYRGIRHRRNLPVRGQKTKTNARTRKGPKRAIGGKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL5_STRPG
Sequence: MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDAVSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTTANTDEESRELLKGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y8179_RHILO
Sequence: MRNMVNKDQVAGLAKQLKGSVKQAAGKATGNRRTQAEGMADKVAGKVQKAYGDVKDKVKKAF
What are the official names of this protein?
UPF0337 protein mll8179.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: SYFM_HUMAN
Sequence: MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKYPAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRF
What is the function of this protein?
Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.  To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.
What are the official names of this protein?
Phenylalanine--tRNA ligase, mitochondrial, Phenylalanyl-tRNA synthetase, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: LPXA_AERHH
Sequence: MIDQTAIIHDTAVVHESAVIGKGVEIGPFSVIGAEVEIGDNTWVSSHVVIKGPTKIGRGNKIFQHTSIGEDCQDKKYAGERTFLEIGDNNVFRENCTVHRGTIQDQSLTRIGSGNLFMVNVHVAHDCIIGDNCIFANNATLAGHVVIGDFVIFGGLSAIHQFGRVGSHAFVGGCAALNKDVPPYVMAAGNYAKPFGVNSEGLRRRGYTPEAISAVKRAYKEIFRSGKTIEEVLPVLTEMAQAEPAIQLYVDFLKDNERGIIRA
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U728_BRAFL
Sequence: MPANAKVTIRYGKYEACGTVEYREDRLDGLQAVLKADGHEVELKQIEDWNVVELIVNGETVYTCNITELDFGGDGKLDPLCAEALQAVQTAY
What are the official names of this protein?
UPF0728 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0728 family.
Protein: ATPF_CHLPD
Sequence: MLTSGVILLNGGLLSPNPGLIFWTTVSFVIVLLILRKLAWGPIISALEEREKGIQSSIDRAHKAKDEAEEILRKNRELLAKADAESDKIIREGKEYGEKLRAGIAEKAQAEAAKMISMAKEEIEQEKRRALDVLRNEVAELAVMGAEKIIKTSLDADMQKKIVDSMIQDLSTKRN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PANC_ALIB4
Sequence: MQVLKTIEELQNIRKNSLGKVGLVPTMGALHNGHISLIKQARNENDIVIVSIFVNPTQFLPGEDLDAYPRRDEADKKICQMCKVNYVFMPEISTMYTKEEVLVKAPNKSYILEGKTRPGHFDGVLQVVLKLFNLTQPTNAYFGKKDAQQLTLIQQMVKNFFLPINIVPCDIVREEDGLALSSRNIYLNPTQRKDALLISKSLYMAGSLISSGERSVKAVKDKIYEVMSILDVEYVAIVDKEFNELETIEPTNTIILVVARFGNTRLLDNIWL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_ECOSE
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: MASTD_VESMG
Sequence: INLKAIAAMAKKLL
What is the function of this protein?
Shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E. coli ATCC 25922 (MIC=3. 0 ug/ml), the Gram-positive bacteria S. aureus ATCC 2592 (MIC=1. 5 ug/ml) and the fungus C. albicans ATCC 2002 (MIC=12. 0 ug/ml).
What are the official names of this protein?
Mastoparan-like peptide 12d.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FHIT_RAT
Sequence: MSFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLRPVERFRDLRPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHDREEEDSPAFWRSEEEMAAEAEVLRAYFQA
What is the function of this protein?
Possesses dinucleoside triphosphate hydrolase activity (By similarity).  Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP (By similarity).  Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP (By similarity).  Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate (By similarity).  Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Exhibits adenylylsulfate-ammonia adenylyltransferase, catalyzing the ammonolysis of adenosine 5'-phosphosulfate resulting in the formation of adenosine 5'-phosphoramidate (By similarity).  Also catalyzes the ammonolysis of adenosine 5-phosphorofluoridate and diadenosine triphosphate (By similarity).  Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5 (By similarity).  Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways (By similarity).  Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis (By similarity).  Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity (By similarity) Functions as tumor suppressor (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: QUEA_STAAM
Sequence: MNIEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFKDIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRIKVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDDPDRYQTVYAKESGSAAAPTAGLHFTDELLTEIKNKGVNIAFVTLHVGLGTFRPVSVDDVNDHEMHSEYYQMTQETADLLNDTKSKGHRIISVGTTSTRTLETIRRDHDKFVETSGWTNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSTRENVLNAYKTAVNLEYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PHOPR
Sequence: MIYRLARSVFFQLDAEKAHDLAIQNFSRFTGTPLDLFYRQHVPDRPVEVMGIKFKNPVGLAAGLDKNGECIDAFGAMGFGFVEVGTVTPRPQSGNEKPRLFRVLPAEGLINRFGFNNLGVDNLVENVKKSKYDGVIGINIGKNKDTPIEKGAEDYLICMDKVYEHAGYIAVNISSPNTPGLRSLQYGEALDDLLSQLKAKQEELAAKHGKYVPLALKIAPDLEDHEIVQIAESLIKNKIDGVIGTNTTLDRTLVKGMPHCDEMGGLSGRPLQNRSTEVIRRLAEELNGALPIIGVGGIDSAISAREKMNAGAQLVQIYSGFIYHGPKLVKDIVMNS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MNTP_NEIG1
Sequence: MSLYALLLVALGMSMDAFAVALAKGAAVRMPPRKIAATALVFGTVEAFMPLAGWVGGFYAKPFISEWDHWVAFVLLGGLGLKMMREGLSGEAEDVRESKQESLWMTVLTAFGTSIDSMIVGVGLAFMEVNIAFAAAVIGMAATVMVTIGLTAGKAFGVLFGRRAEFAGGLVLIAIGTWTLLSHLGLIQ
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPB2_SHEFN
Sequence: MMDRKNASPNSGTVIAIRGSVVDILFAEQLPPIRSLLTTGHQHQILIEVFSQLDEHRVRCIALTPTQGLARGMLVEDSGGPLLAPVGKTILSRMFDVFGNAIDRKAPPIGTQWRSVHNEPPAIAQLATKSQVFETGIKMIDVLMPLERGGKAGLFGGAGVGKTVLLTEMIHNMVGQHAGVSIFCGIGERCREGEELYREMKTAGVLDNMVMVFGQMNEPPGARFRVGHAALTMAEYFRDDEHRDVLLLIDNIFRFIQAGMEVSGLMGQMPARLGYQPTLGTELSQLEDRIANTDSGAITSIQAVYVPADDFTDPAAVHTFSHLSASIVLSRKRASEGLYPAIDPLLSNSKMATPSIIGRRHYDLAQKIRSTLAQYAELKDIIAMLGMEQLSPADHKIVARARRLERFFTQPFFTTEQFTSMPGKLVSLNDALDGCERILHDEFKDYPESALYMIGSIDEAVSKYRPKLDRVNSQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLGX_ECOL5
Sequence: MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNDRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALMENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: THIO3_DICDI
Sequence: MSKVIHVTSNEELDKYLQHQRVVVDFSAEWCGPCRAIAPVFDKLSNEFTTFTFVHVDIDKVNTHPIVKEIRSVPTFYFYVNGAKVSEFSGANEATLRSTLEANI
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin-3, Trx-3.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.