PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_PSEP1
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQDDVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYGGQGLYEPLDLQIAQCKLMTAGVVGAAEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLINLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHARIQSLIDTLRQAVESRHRG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD2_ARATH
Sequence: MAMHTVRLSPATQLHGGISSNLSPPNRKPNNSIVRYGCGSSKRFRIVTVLASLRENDANGRDNSVRAMEVKKIFEDSPLLPKPLSSNQLTESVSNGSRVRVAYQGVRGAYSESAAEKAYPNCEAVPCEEFDTAFEAVERWLVDRAVLPIENSLGGSIHRNYDLLLRHNLHIVGEVKLAVRHCLLANHGVNIEDLRRVLSHPQALAQCENTLTKLGLVREAVDDTAGAAKQIAFENLNDAAAVASEKAAKIYGLNIVAKDIQDDCDNVTRFLMLAREPIIPGTNRLFKTSIVFSLEEGPGVLFKALAVFALRQINLTKIESRPLRKHPLRASGGLKYFDYLFYVDFEASMADEVAQNALRHLEEFATFLRVLGSYPVDTTML
What is the function of this protein?
Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025).  Dehydratase that uses arogenate and prephenate as substrates (PubMed:17726025).  Utilzes more efficiently arogenate than prephenate (PubMed:17726025).  Required for chloroplast division prior to ARC5, but in an ARC3- and ARC6-dependent manner, especially involved in the Z-ring formation (PubMed:30252596).
What are the official names of this protein?
Arogenate dehydratase/prephenate dehydratase 2, chloroplastic, AtADT2, AtPDT2.
Protein: HIS1_PETMO
Sequence: MTTISAALPSGRLLEDSKAFLKKIGINVKEPAKRELISYENGYAFYFPRAFDVPVYVENGVDIGICGSDVVLERNNEVYIPLELPFGKCRMSIILPENREISFQNMEGYKIATKYPEITKNFFSEKGLKVKILKLNGAVELAAKTGIADAIVDIVDTGNTIKANNLKEAYKIMDISAVLLVNRITQKTKFDFINDLINKAKNYKNGVKGH
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APO1_COPRA
Sequence: VPGGLXPPPEYVGPKLVNDADHPWEPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAIVEGFNFNYEGAVFVTYFAHIVDGNLVTDLLSIGGKTNLTGEDTGAPAIIGGLNTHSVFEGDASMTRDDFHFGDNHSFNQTLFDQFVEYSNTYGGGFYNQEVAGHLRRRRIEQSIATNPEFDFTSPRFFTAFAESSFPYSFFVDGRITERPGGLSMENATLFFRDHKMPDDFWRNVNGEMTFTGTPDPNSAPSNLALGH
What is the function of this protein?
Aromatic peroxidase that oxidizes aryl alcohols into the corresponding aldehydes and then into the corresponding benzoic acids.  Catalyzes the regioselective peroxide-dependent hydroxylation of naphthalene to 1-naphthol and to a far lesser extent 2-naphthol via a naphthalene 1,2-oxide intermediate.  Halogenates phenol to 2-bromophenol and 4-bromophenol.  Oxidizes the sulfur-containing heterocycle dibenzothiophene to yield sulfoxidation products, and trace amounts of ring-hydroxylation products.
What are the official names of this protein?
Aromatic peroxygenase.
What is the protein family that this protein belongs to?
Belongs to the chloroperoxidase family.
Protein: RL33_HAEIN
Sequence: MAAKGAREKIRLVSTAETGHFYTTDKNKRNMPEKMEIKKFDPVVRKHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS11_SHEAM
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATAGGSGFRGSRKSTPFAAQVAAERAGVAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HSLU_RHILO
Sequence: MTTFSPREIVSELDRFIIGQKDAKRAVAIALRNRWRRQQLEGQMREEVMPKNILMIGPTGVGKTEISRRLARLAGAPFVKVEATKFTEVGYVGRDVEQIIRDLVEIAIGLVREKMREDVKARAHINAEERVLEALVGKTASPATRDSFRKKLRDGELDDKEIEIEVADTGNGGMPGFEIPGMPGANIGVLNINDMLSKAMGGKKTKSRKTTVKESYDLLVSDESDKLLDQDEVVRRALDATENDGIVFLDEIDKIAARSDISGGPSREGVQRDLLPLVEGTTVATKYGPVKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELRALEKQDFVRILTETEASLIKQYIALMKTEGVDLTFTDDAIDSLAGIAVDLNDSVENIGARRLQTVMERVLDEISYDAPDRNGTSVTIDAAYVEKHVGDLSRNTDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_AETCO
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AAEX_ESCF3
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNF6_MOUSE
Sequence: MDPSRSRSGGSGEESSFQENERRWQQERLHREEAYYQFINELSDEDYRLMRDHNLLGTPGEITSEELQQRLERAKEQLASQPGSDSAASDGDSESLRAHSDEDSLLRWLNTFRRTGNVTRSGQNGNQSWRAVSRTNPNSGEFGFSLEIHINPDNRGSEMHGEDSTDIPLSGVNREHRQQRPSSPVARRTRSQTSMSSSGPRGRRGARRQGSVQGSFATLGRLRNGIGVALGVPRVSAPRTNVINSHTNQSDGSTLRQGGRQRFGAAHIWENGARSNVTVRNTNQRLEPIRLRPAFSSRSRSPIQRQNGTVHHNSQRQGRPVQQTGRNRSVRHRGVTRVFLEQGREHRGTDYTPLSNSRLVSRITVEEGESSRSSAATQRHPAITLDLQVRRIRPGETRDRDSIANRTRSRAGLAESTVESTSGGFHRTISHLERSGVRTYVSTITVPLRRISENDVVEPSSVALRSILRQIMTGFGELSSLMEVEPASENQSNGQRLPEVYLELSNGDAADDSGQHGRASSQASQAQDGAEMLAVREPAPPQARPSGSRSRRQLGRADSVVEAGTLPILRLAHFFLLNEGDDDPIRGLTKEQIDNLSTRSYEQDGVDSELGKVCSVCISDYVAGNKLRQLPCLHEFHIHCIDRWLSENCTCPVCRRPVLEFGATSSG
What is the function of this protein?
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation.  Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover.  Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity.  May also bind DNA and function as a transcriptional regulator.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF6, RING-type E3 ubiquitin transferase RNF6, RLIM-like protein.
What is the protein family that this protein belongs to?
Belongs to the RNF12 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, axon. Nucleus, PML body. Note=Localizes to the PML nuclear bodies in Sertoli cells.
Protein: TM117_DANRE
Sequence: MSSQSLHDCLRGRCLGVLRRMEIIGRFRYYFQHPWSRLLVSYLVTFFNFLIFAEDPVSHSQKEAHMSVVGNCFSFIISKYPAGFWSVLKVLLWVLAIICGLIAGKFIFHRRLFGRVLRLKMFREDHGSWMTMFFSTILSLFIFSHIYNLLLLMSVRMRPYMVTEYMGIRNESFMKMAAVGTWMGDFVTAWMVTDMMLQDTHYPDWGRTARHLWRQGHNRIVLFWTVLICLTSVVVLVISTDWIRWDNLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDLDMNLPGLSTTQLKIRLPVCKRIFKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPYEYGQYVGPGEKIYTVEDPDTLQDFNRSMLTWEWRSTNIDPRTNQTFNQSNAI
What is the function of this protein?
May be involved in endoplasmic reticulum (ER) stress-induced cell death pathway.
What are the official names of this protein?
Transmembrane protein 117.
What is the protein family that this protein belongs to?
Belongs to the TMEM117 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDLI3_HUMAN
Sequence: MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHNIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA
What is the function of this protein?
May play a role in the organization of actin filament arrays within muscle cells.
What are the official names of this protein?
PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.
Protein: MINJ_LACCC
Sequence: MAVVVALLINPVGLVFWLALGLTIWFAVNRTDRERRRYLRAIHPKHPEIGRFFWIGLVVGALVSLVMVIGRLQISLAALLALSGLTLVALLFSKWRFSPWWLGLASLAAVGQSGLLAEQHAANLAILVGLLWLTQAGLARFNRGDEIESPVIQQDRRQRQSAAFELRQLFWVPLILPVAVENVSNLPLLAVTVQSLTFVGLPLLLGATFMTPRDRAQTAWRRSWPWYGGAGGVLIVYGIVARTMTLPLLVSLVFPAVVSLVLVGGFIWQGRQVHLTVTLADQGVVLIGVVPHTPAAEMGLQPGDRVLACNHHSVNNSRELYDAIQKEPTYCRLRLRQADGELRLAETAIFAGAPHELGMILFPEETA
What is the function of this protein?
The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle.  MinJ acts as a bridge between DivIVA and MinD.  May modulate activity and localization of MinD and MinC through direct interaction with MinD (By similarity).
What are the official names of this protein?
Probable cell division topological determinant MinJ.
What is the protein family that this protein belongs to?
Belongs to the MinJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_LEGPH
Sequence: MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTGKKGDDLTIKVPVGTMVYDADTGELLADISQPGIPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCVLLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLEWKDKVFSISAIESKGTQELCYALMQLIDEMKESEA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STRPI
Sequence: MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGFRKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQDWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAAENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVTFPEDYQAEDLAGKEAQFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKELAAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDMYFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYNMEVAQVQNLLSADMLKHDITIKKAVELITSTATVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TSAD_LIMRJ
Sequence: MTERTLTLAFESSCDETSVAVIENGTKILSNIVATQIDSHQRFGGVVPEVASRHHIEQITKCTNEALEQADVDYNDLDAVAVTYGPGLVGSLLIGVTAAKAIAWAHNLPLVPVNHMAGHIYAARYVGEFQYPQMALLVSGGHTELVYMPSEHEYQIIGETRDDAAGEAYDKIGRVLGVNYPAGKTIDEWAAKGKDTFNFPRAMEKEDNYDFSFSGLKSAFINTVHNADQRGEKLDKYDLAASFQQSVIDVLAEKTMRALDDYPVKQLILAGGVAANHGLRARLDHDMKEFHPDVPMLQAPLKLCGDNAAMIGAAGYVNYKHGDRAGLDLNAVPGLMFDRIQSK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL55_ARATH
Sequence: MAFNHRKMLLSCLQFKDLRFCFRQYPPPPPPPPPPRELSLLLPTSICVVGSIILFLFLVFFLYLHITQQRRISAASVTPGDTNQQEDEDETEERDFSDFHHVWQIPTVGLHRSAINSITVVGFKKGEGIIDGTECSVCLNEFEEDESLRLLPKCSHAFHLNCIDTWLLSHKNCPLCRAPVLLITEPPHQETETNHQPDSESSNDLRGRQDSSRSRRNHNIFLPRAQSDLANYCGSGRVENVRRSFSIGGSLSLCDGINNATRSGRQFYTSFSANLFSSSRRVRNEQPIPQNQMPSVTGNTS
What is the function of this protein?
E3 ubiquitin-protein ligase that may be involved in positive regulation of programmed cell death (PCD) by facilitating degradation of negative regulators of PCD.  May be involved in the early steps of the plant defense signaling pathway.  Undergoes auto-ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase RING1, RING-H2 finger protein ATL55, RING-type E3 ubiquitin transferase ATL55.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SECA_PSEE4
Sequence: MFAPLLKKLFGSKNEREIKRMLKTVSAVNALEEKMVALSDEQLRGKTAEFKERLAKGETLDQLLPEAFAVAREAGKRVMGMRHFDVQLIGGMTLHEGMIAEMRTGEGKTLVGTLAVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLTVGIVSAFQPPEEKRAAYAADITYGTNNEFGFDYLRDNMAFSQDEKFQRELNFSVIDEVDSILIDEARTPLIISGQAEDSSKLYIEINRLIPRLTQHIEEVEGQVTQEGHYTIDEKSRQVELNEAGHQFIEDMLTQSGLLAEGESLYSAHNLGLLTHVYAGLRAHKLFHRNVEYIVQDGQILLIDEHTGRTMPGRRLSEGLHQAIEAKENLNIQAESQTLASTTFQNYFRLYTKLSGMTGTADTEAFEFAQIYNLNVMVIPPNKPLARKDFNDLVYLTADEKYAAIITDIKESMALGRPVLVGTATIETSEHMSNLLKKEGIDHKVLNAKYHEKEAEIIAQAGAPGALTIATNMAGRGTDILLGGNWEAEVAALDNPTPEQIAQIKADWQKRHQQVLEAGGLHVIASERHESRRIDNQLRGRAGRQGDAGSSRFYLSLEDSLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEYDDVANEQRKVIYHMRNSLLAAQNIGDTIAEFRQEVLDATISQHIPPQSLPEQWDVAGLEASLASDFAMKLPIQQWLDEDDHLYEETLRERLIKEITDAYNEKEDQAGEDALRTFEKQILLRVLDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFTLFQELLESIKRDTIRVLSHVQVRREDPAEEEARLRREAEELASRMQFQHAAAPGMESDLQASEEGAEVAVAAAPVRNDQKLGRNEPCWCGSGKKFKHCHGQIE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: YVBA_VACCC
Sequence: MVIYCSNSLGAYCKLVINKVAVLLTYFCFVALTNAQFFVSDILVHGKIPPNHLIIQYPSVSRSPRLDTTYPLCESIGVNSRVPLSILFGFLINGTCSPLDMNLETNP
What are the official names of this protein?
Uncharacterized 11.8 kDa protein.
Protein: RL31B_PSEE4
Sequence: MKAGIHPAYRPVLFHDTAADVYFLIGSTVDTDRTQVHSDGQTYPYVALDVSSASHPVYTGQQRKTTVEGRVAGFNKRFAGFQATR
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: AAEB_ECOLU
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIG_LEGPC
Sequence: MWNLAGKELSSRLLLGTACYPSLEHMQQAIHNSGTEVITISIKRQTSAGLDGESFWQAVKKLDCHLLPNTAGCRNAEAAINTAEIARELFNTHWIKLEVIGDDYNLQPEPFELIKAARILIDRGFEVFPYCTDDLVLCQKLVDAGCKILMPWGAPIGSGKGLINPYALETLRYRFPDITLIIDAGIGKPSHAVQVMELGFDGVLLNTAVALANHPALMATAFRHAVIAGHQAFIGGMMSERNVAHPSTPLIDTPFWHQVNNL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_RICFE
Sequence: MKEAKIENIDFGNALSERYLAYALSTIMSRSLPDVRDGLKPVHRRLLYAMLQLRLEPNSGYKKCARVVGDVIGKYHPHGDVAVYDTLVRLAQHFSLRYPLIDGQGNFGSIDGDNAAAMRYTESRMTEICTLLMVDIEKDTVDFRPTYDDSDLEPVIMPASFPNLLANGSEGIAVGMATNIPPHNLHELCDALVHLIDHPKAEISDMMNFIKGPDFPTGGIIIDKAELINAAYSTGRGSFRMRSRWEKEELSYGTYQIVVTEIPYQVQKSKLIEQIAILLKDKKIPLVSNIRDESTDIIRLVIEPRDRGCDPQIVMESLFKLTNLESRIQLNMNVIGSNNVPRVMNILEVLQEFLAHRQNIVTRRSTYLLNKIKHRLEILEGLRIAYLNLDEIIKIIREEDEPKAIMMERFKLTEIQVEAILNTRLRSLRKLEEQEIINEHSNLQKQQAILEEILNNPKELWKIVKKEIKAVQTKFGLNTVIGARRTSFEEVTLTNQVVDITAFITKEPITIICSKMGWVRSLKGHNTDLSTIKYKEGDAEKFIIEAYTTDKILIVSSEGRFFTLLADNISKGKGTGESIKLLVDIGNNDITNILVHKSDQLLLLASSIGKGFLVNSNEVMAQTKTGKQIMNVPDGHTCIACLPVNGDSIACIGESRKLLVFNIDEIPEMKKGQGVTLQKFKNAKLLDIKIFNKEDGLSWNNNGKVKLEKNIIAFLGKRGSTGKLPPMGFHKNNRFSS
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NEMU_DROME
Sequence: MSAKYTLIFALAALCCLVFSTEAAAQRSRVLSSRRGSELVEKTSDNKEDSELAAQEQDLERQEQEEQNDRLEGRSDDVAEGSDNKEDKETATNNKDTIVKPNKDDARARRIVRAGRRRGGRRGGRRGGRRSARKSVRRGGRRGGRRRGGRRGRGGARRRTSVKRRSGKGNKA
What is the function of this protein?
Antimicrobial protein which is essential for the homeostatic regulation of sleep.  Promotes sleep following sleep deprivation or bacterial infection and increases survival following bacterial infection.  Likely to promote survival to bacterial infection in two ways; by contributing to the innate immune response and by promoting sleep during sickness to aid recovery.
What are the official names of this protein?
Protein nemuri.
What are the subcellular locations of this protein?
Secreted.
Protein: Y233_MYCGE
Sequence: MIKINISQNFLVAKGHALFAEKGKDIVCAAISGIIFGGVAWFEPDKIEFTENKLVPSIALKLIDPTPNVAVAFSVITVQLKAIANSYPNHIVINEESYE
What are the official names of this protein?
Uncharacterized protein MG233.
What is the protein family that this protein belongs to?
To B.subtilis YsxB.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YWQH_BACSU
Sequence: MGYESMLADIKSSLNGKISDVEDKIEKLKKAKKDIDTLQEEAITEIKEIVKPELGKHWTGTKADDFDKGREEAKSEASKIVNDKYNEYMASINGKIFDLEWDKAKYASELFIANGAADLLKKGEEFAEEVGNTISKLKWW
What are the official names of this protein?
Protein YwqH.
Protein: YIDD_ECO81
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDPA_FRATF
Sequence: MISNFILFALFIVTIALITKPLGSYIFRVFNNERTYLDWLAKPFQRVYLLVLGESSKKEQTAKAYFFSLVSFSVMAFIFVLVILLLQGILPLNPQEIKGMSFPQALNTAVSFITNTNWQSYSGETGVSYFAQMLALAVQNFVSAAVGLCVAIALIRSVARHETATIGNFWNDLGKGVFWILLPISIVIAIVYIFQGVPQNVMAYLHVHTLAGTEQIIPQGPIASQEAIKSLGTNGGGFFNANSAHPYENPTVITNYIQMVSIFAIAAALTYTFGKWVGNTKQGWLIFGVMLVLFIISLVVMTISELHGLDFLHSKDIQDIYGQVGHLSNMEGKESRFGVFYSTLYNTVSTSASDGGVNSVLDSYSPLAGMMAMLNMAIGEVIFGGVGAGFYGFFMFLMLAVFIGSLMIGRAPSFLGKRIEANDMKWTMFALLIFPCCVLVFTGLAAVIPSVHQTLTNSGAHGFSEILYAYISGANNNGSAFAGLSANTNYLNITIALSMLIGRFGVIFAVIMLAGSLVKKKRSLQMSEISSLDTTSFIFAILVFFTILLIGGLTIFPALGLGPILDQLNLNFL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.