PharMolix/UniProtQA huggingface dataset:
Protein: 3SOA1_DENAN
Sequence: MKTLLLTLLVVTIVCLDLAHTRICYSHKLLQAKTTKTCEENSCYKRSLPKIPLIIIGRGCGCPLTLPFLRIKCCTSDKCN
What is the function of this protein?
Is cytotoxic against human non-small cell lung adenocarcinoma A-549 cells (LC(50)=56 ug/ml), breast adenocarcinoma MDA-MBsy-231 cells (LC(50)=62 ug/ml) and colorectal adenocarcinoma HT-29 cells (LC(50)=110 ug/ml).  Shows low hemolytic activity against human erythrocytes (LC(50)>600 ug/ml).  Is also cytotoxic against human umbilical vein endothelial HUVEC cells (57 ug/ml) indicating no differential activity against cell lines derived from neoplastic tissues.
What are the official names of this protein?
Toxin C13S1C1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group X sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RABU_DICDI
Sequence: MEKKKNLEQDCIFRIVIIGYDYECGIKSLLKKFTLGEFSPFPESQVGVDFDIKTINVDNQDIKLQIWPQNKYFNDTSDKRDFLYKGAHGYLLVYGCHSQKSFDNLLNDWMVQIDKFSNEFSKRNLVLVCNNSETPETYMTKPNYLVDSNITKQWANSKNIPFFEINPKENFNVDEPFIQLARLIKNQNFINSTK
What are the official names of this protein?
Ras-related protein RabU.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: DCD_CAMLR
Sequence: MGLKADNWIKKMALEHNMIEPFCEANIGKGIVSYGLSSYGYDIRVGREFKIFTNVNSTVVDPKNFVEENVVDFVGDVCIVPANSFALARTVEYFKMPNDVLAICLGKSTYARCGIIVNVTPFEPGFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDEPCDVTYADKKGKYQAQTGITLPRILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PRMA_PROMA
Sequence: MIQSTEFFWWKFELVFPPDVEESFLWFLNMAGIKSYAIERSPDNLQDQTLMVWLPSHEWLKKDREEFENSLLALNKAFREDVLNTKWEKIIDEDWSSSWKKFWKADPVGSKILILPSWLELPDIYSNRIVIKLDPGSAFGTGSHPTTRLCLEDLERNPPLGKKVVDIGCGSGVLGIAAIKLGAKEVRAIDIDSLAVRATSENIVLNNLSQKQLSVSLGSIENLANQLNPLSADLLICNTLSPVIKELAPYFFKLTHSYSRLCLSGLLVAQVEDITNFLSILGWELIDSYSSDNWALIRLCRNHP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCP2_SCHPO
Sequence: MSFTNATFSQVLDDLSARFILNLPAEEQSSVERLCFQIEQAHWFYEDFIRAQNDQLPSLGLRVFSAKLFAHCPLLWKWSKVHEEAFDDFLRYKTRIPVRGAIMLDMSMQQCVLVKGWKASSGWGFPKGKIDKDESDVDCAIREVYEETGFDCSSRINPNEFIDMTIRGQNVRLYIIPGISLDTRFESRTRKEISKIEWHNLMDLPTFKKNKPQTMKNKFYMVIPFLAPLKKWIKKRNIANNTTKEKNISVDVDADASSQLLSLLKSSTAPSDLATPQPSTFPQPPVESHSSFDIKQKILHLLNEGNEPKSPIQLPPVSNLPLNPPIQSSNSRLSHDNNSFDPFAYLGLDPKNPSASFPRVVSQNNMLTNKPVLNNHFQQSMYSNLLKDQNSVQHLFAASDMPSPMELPSPSTVYHQVFYPPTSTSVSSYGLGKTPQPAYGSSSPYVNGHQTQQISSLPPFQSQTQFLARNSDNSGQSYNSEGDSNSKRLLSMLSQQDTTPSSSTLSKEANVQLANLFLTPNSLETKKFSDNSQGEEISDNLHGESCNNPNANSVHSAQLLQALLHPSATETKEETPKKTSDSLSLLTLLKSGLPTPANDLQNKSQNNERKASSQVKELEVKNYSKSTDLLKKTLRIPRNDEPLEAANQFDLLKVSPQQKSEVPPKRNELSQSKLKNRKKKENSETNKNHVDMSPGFVKILKRSPLADQKKEDTQESDFKGSDDHFLSYLQSVVSSNSNGLH
What is the function of this protein?
Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.  Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.  Decapping is the major pathway of mRNA degradation in yeast.  It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body.
What are the official names of this protein?
mRNA decapping complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DCP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: Y1355_CAMJ8
Sequence: MDERILEFIKNEQLLSWAMIDEKGVYTASAFYAFDEKNLAFIIASHEDTKHIRLASENSSIALNIAKESKIAFLKGVQAKAEFKMASKEQMKIYFSKFPFAKFDKSAKIYALELFWLKFTNNALGLSKKLEFYKK
What are the official names of this protein?
UPF0306 protein C8J_1355.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: IBP_CARCR
Sequence: QGDKRDICRLPPEQGPCKGRIPRYFYNPASRMCESFIYGGCKGNKNNFKTKAECVRACRPPERPGVCPKTSGPGICLHGCDSDSDCKEGQKCCFDGCGYICLTVAPSGSP
What is the function of this protein?
The first domain inhibits trypsin; the second one inhibitis subtilisin.
What are the official names of this protein?
Chelonianin, Basic protease inhibitor, RTPI.
Protein: PSIK_PSICU
Sequence: MAFDLKTEDGLITYLTKHLSLDVDTSGVKRLSGGFVNVTWRIKLNAPYQGHTSIILKHAQPHMSTDEDFKIGVERSVYEYQAIKLMMANREVLGGVDGIVSVPEGLNYDLENNALIMQDVGKMKTLLDYVTAKPPLATDIARLVGTEIGGFVARLHNIGRERRDDPEFKFFSGNIVGRTTSDQLYQTIIPNAAKYGVDDPLLPTVVKDLVDDVMHSEETLVMADLWSGNILLQLEEGNPSKLQKIYILDWELCKYGPASLDLGYFLGDCYLISRFQDEQVGTTMRQAYLQSYARTSKHSINYAKVTAGIAAHIVMWTDFMQWGSEEERINFVKKGVAAFHDARGNNDNGEITSTLLKESSTA
What is the function of this protein?
4-hydroxytryptamine kinase; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product (PubMed:28763571, PubMed:31150155, PubMed:32101345).  The first step in the pathway is the decarboxylation of L-tryptophan to tryptamine by the decarboxylase psiD (PubMed:28763571, PubMed:31150155).  4-hydroxy-L-tryptophan is accepted as substrate by psiD as well (PubMed:28763571).  The cytochrome P450 monooxygenase psiH then converts tryptamine to 4-hydroxytryptamine (PubMed:28763571).  The kinase psiK catalyzes the 4-O-phosphorylation step by converting 4-hydroxytryptamine into norbaeocystin (PubMed:28763571, PubMed:31150155, PubMed:32101345, PubMed:35583969).  The methyltransferase psiM then catalyzes iterative methyl transfer to the amino group of norbaeocystin to yield psilocybin via a monomethylated intermediate, baeocystin (PubMed:28763571, PubMed:31150155).  4-hydroxy-6-methyl-l-tryptophancan also be converted the decarboxylase PsiD, kinase PsiK, and methyltransferase PsiM into respectively 6-methyl-norbaeocystin, 6-methylbaeocystin, and 6-methylpsilocybin (PubMed:31150155).  PsiK kinase can also turn psilocin into psilocybin (PubMed:28763571, PubMed:35583969).  This activity may represent a protective mechanism to rephosphorylate the unstable psilocin to the stable psilocybin in case of intracellular ester cleavage (PubMed:28763571, PubMed:35583969).  Moreover, psiK is able to O-phosphorylate the quaternary amine 4-hydroxy-N,N,N-trimethyltryptamine (4-OH-TMT) to yield aeruginascin, another bioactive compound found in Psilocybe species (PubMed:35583969).
What are the official names of this protein?
4-hydroxytryptamine kinase, Psilocybin biosynthesis kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: PDXT_MYCA9
Sequence: MSPLVGVLALQGDVREHVAALKDSGAEALGVRRPEELGKVDGLVIPGGESTTMSNLLRVFELLDPLTERLRAGLPVYGSCAGMILLASEILDTRPDAVALGAIDMTVRRNAFGRQVDSFEGDLDFTGVDGAMHAVFIRAPWVERVGDDVEVLASAQGHPVAVRQGSALATAFHPEVTGDRRVHQLFVDMVRAG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RL34_STRMK
Sequence: MATKRTYQPSNLKRKRDHGFRARMKTADGRKILSRRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TNF11_MOUSE
Sequence: MRRASRDYGKYLRSSEEMGSGPGVPHEGPLHPAPSAPAPAPPPAASRSMFLALLGLGLGQVVCSIALFLYFRAQMDPNRISEDSTHCFYRILRLHENADLQDSTLESEDTLPDSCRRMKQAFQGAVQKELQHIVGPQRFSGAPAMMEGSWLDVAQRGKPEAQPFAHLTINAASIPSGSHKVTLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPTDYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISIQVSNPSLLDPDQDATYFGAFKVQDID
What is the function of this protein?
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK.  Osteoclast differentiation and activation factor (PubMed:22437732).  Augments the ability of dendritic cells to stimulate naive T-cell proliferation.  May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response.  May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (By similarity).  Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts (PubMed:18586671, PubMed:24039232, PubMed:27336669).  During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation (PubMed:23395171, PubMed:26644563).
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted.
Protein: ERAL1_MOUSE
Sequence: MAAPRRYCAGLVRALLGARQVGSHAGREWLAPPGCLLGNQARCVSCVVGSTFSGPLLASASSRYGQDSALDRILGFSQPDSSLVPSVPAVSVHRDEQNLLLVHTPDMPENPRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSKKVHTTRCQALGVITEKETQVILLDTPGIISPVKQKRHHLERSLLEDPWTSMESADLVVVLVDVSDKWTRSRLNPQVLQCLTKFSQVPSILVLNKVDCLKQKSVLLELTAALTEGVVNGKKLNIKQALRSRSSTHCPGPETEGPNAHSVRNPQRIGWPYFQEIFMLSALNNKDVNTLKQYLLTQAQPGPWEFHSGVLTSQTPEEICANKIREKLLEYLPEEVPYGVQQKTVIWEEGPSGELVIQQNLLVPKESHVRILIGQKGLLISQIAQEVGRDLMDIFHCDVLIRLSVKLLK
What is the function of this protein?
Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly.  Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region.  May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity).
What are the official names of this protein?
GTPase Era, mitochondrial, M-ERA, Conserved ERA-like GTPase, CEGA, ERA-W, ERA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes on the matrix side on the mitochondrial inner membrane.
Protein: STP11_ARATH
Sequence: MAGGAFIDESGHGGDYEGRVTAFVMITCIVAAMGGLLFGYDIGISGGVISMEDFLTKFFPDVLRQMQNKRGRETEYCKYDNELLTLFTSSLYLAALFASFLASTITRLFGRKVSMVIGSLAFLSGALLNGLAINLEMLIIGRLFLGVGVGFANQSVPLYLSEMAPAKIRGALNIGFQLAITIGILAANIVNYVTPKLQNGIGWRLSLGLAGVPAVMMLVGCFFLPDTPNSILERGNKEKAKEMLQKIRGTMEVEHEFNELCNACEAAKKVKHPWTNIMQARYRPQLTFCTFIPFFQQLTGINVIMFYAPVLFKTIGFGNDASLISAVITGLVNVLSTIVSIYSVDKFGRRALFLQGGFQMIVTQIAVGSMIGWKFGFNGEGNLSGVDADIILALICLYVAGFAWSWGPLGWLVPSEICPLEIRSAGQSLNVSVNMFFTFFIGQFFLTMLCHMKFGLFYFFAGMVLIMTIFIYFLLPETKGVPIEEMGKVWKEHRYWGKYSNNDDGDDVDDDAYF
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.  Can transport glucose, galactose, mannose, xylose and 3-O-methylglucose, but not fructose and ribose.
What are the official names of this protein?
Sugar transport protein 11, Hexose transporter 11.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURR_YERPS
Sequence: MATIKDVAKHAGVSTTTVSHVINKTRFVAENTKAAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEVIEAVENSCYSKGYTLILCNSHNNLDKQKAYLAMLAQKRVDGLLVMCSEYPDQLLGMLEDYRNIPMVVMDWGTARGDFTDSIIDNAFEGGYLAGRYLIERGHRDIGAIPGQLARNTGGGRHQGFLKALEEANIPVREEWIVQGDFEPESGYKAMHQILTQKHRPTAVFCGGDIMAMGAICAADELGLRVPQDISVIGYDNVRNARYFSPALTTIHQPKERLGETAFAMLLDRIVSKREDPQTIEVHPKLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: TYSY_STRPD
Sequence: MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLSA_SALHS
Sequence: MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASSLFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQDDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCME_NITWN
Sequence: MTRKQRRLTMIGGALVVLGIAAALVLNALRDSIVFFSTPMMVSEKHIQPGQRFRLGGLVQTGSLVRGDNLAVSFRVSDGSATLPVSYKGILPDLFREGQGVVAEGALDNSGVFQADTVLAKHDETYMPKEVADALKKQGHWKDDYGAQPGAAEASSKQEVSQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ABI4_ARATH
Sequence: MDPLASQHQHNHLEDNNQTLTHNNPQSDSTTDSSTSSAQRKRKGKGGPDNSKFRYRGVRQRSWGKWVAEIREPRKRTRKWLGTFATAEDAARAYDRAAVYLYGSRAQLNLTPSSPSSVSSSSSSVSAASSPSTSSSSTQTLRPLLPRPAAATVGGGANFGPYGIPFNNNIFLNGGTSMLCPSYGFFPQQQQQQNQMVQMGQFQHQQYQNLHSNTNNNKISDIELTDVPVTNSTSFHHEVALGQEQGGSGCNNNSSMEDLNSLAGSVGSSLSITHPPPLVDPVCSMGLDPGYMVGDGSSTIWPFGGEEEYSHNWGSIWDFIDPILGEFY
What is the function of this protein?
Transcription regulator that probably binds to the GCC-box pathogenesis-related promoter element.  Binds also to the S-box (5'-CACTTCCA-3') photosynthesis-associated nuclear genes-related (PhANGs-related) promoter element, and thus acts as a transcription inhibitor.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.  May have a function in the deetiolation process.  Confers sensitivity to abscisic acid (ABA), and regulates the ABA signaling pathway during seed germination, upon nitrate-mediated lateral root inhibition, in hexokinase-dependent sugar responses (including feed-back regulation of photosynthesis and mobilization of storage lipid during germination), and in response to osmotic stress mediated by NaCl, KCl or mannitol.  Plays a role in sucrose sensing or signaling, especially at low fluence far red light.  Also involved in plant response to glucose treatment, especially at low concentration and in young seedlings.  Required for the trehalose-mediated root inhibition and starch accumulation in cotyledons, probably by inhibiting starch breakdown.  However, seems to not be involved in sugar-mediated senescence.  Required for the ABA-dependent beta-amino-butyric acid (BABA) signaling pathway.  BABA primes ABA synthesis and promotes resistance to drought and salt, and leads to a prime callose accumulation that confers resistance against necrotrophic pathogens such as A. brassicicola and P. cucumerina.  Seems to be involved in resistance to S. sclerotiorum probably by regulating the ABA-mediated stomatal closure apparently by antagonistic interaction with oxalate.  Negative regulator of low water potential-induced Pro accumulation whose effect is decreased by high levels of sugar.
What are the official names of this protein?
Ethylene-responsive transcription factor ABI4, ERF ABI4, Protein ABSCISIC ACID INSENSITIVE 4, Protein GLUCOSE INSENSITIVE 6, Protein IMPAIRED SUCROSE INDUCTION 3, Protein SALOBRENO 5, Protein SUCROSE UNCOUPLED 6, Protein SUGAR INSENSITIVE 5.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HRCA_DESAP
Sequence: MGIDERKKQILRAIVLDYIATAEPVGSRTIARKYGLGISPATIRNEMADLEEMGYLEQPHTSAGRIPSQRGYRYYVDELMEPETPAEEEKLIIKTNYQAKVKSISEVIERTGQLMSQLTSYAALVSTPRVTGSTVQHVQLIAMGGGKAMVLVVTEPEKVHTRVIDLPENITAEDLETVSRVMNAKIRGHSLNDIRITILREIYLELLRHKAVVEYIMDLIEDSGESTEDRVYLGGILNILNQPEFRNVEKMKTLLSLLDQEALLSSLLAEQAGQEEGITVLIGDEFKCDLIQGCSLVSARYGVEGRAVGALAVLGPSRMDYARVTGLVEYLTRNLSRVLEKLYR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: BIOB_VIBCH
Sequence: MEVRHNWTVAEVKALLDKPFMDLLFEAQQVHRLHHPHNHVQVSTLLSIKTGACPEDCKYCPQSAHYRTDVDKERLMEVERVLDAAQKAKNSGSTRFCMGAAWKNPKERDMPLLKEMIRGVKDMGLETCMTLGMLTPDQAQQLAQAGLDYYNHNLDTSPEFYGNIITTRTYQDRLDTLSHVRDAGMKICSGGIIGMGESTNDRAGLLVELANLPTHPESVPINMLVKVKGTPLEQVDDVEPFDFVRLIAVARIMMPKSAVRLSAGREKMNEQMQALCFMAGANSIFYGCKLLTTPNPAEDSDMLLFKKLGINREQVAQKPDEITENELLDRVVERVAARPTASDLFYDAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CP94_CONIM
Sequence: MHRSLAGSAVLMLLLLFALGNFVGVQPGLVTRDADNGQLMDNRRNLRLERKTMSLFKSLDKRADCSTYCFGMGICQSGCYCGPGHACMPNGR
What is the function of this protein?
Probable neurotoxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Im9.4, Conopeptide im022.
What is the protein family that this protein belongs to?
Belongs to the conotoxin P superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NRP2_HUMAN
Sequence: MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFDPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDSKPTVETLGPTVKSEETTTPYPTEEEATECGENCSFEDDKDLQLPSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRISTDVPLENCMEPISAFAGENFKVDIPEIHEREGYEDEIDDEYEVDWSNSSSATSGSGAPSTDKEKSWLYTLDPILITIIAMSSLGVLLGATCAGLLLYCTCSYSGLSSRSCTTLENYNFELYDGLKHKVKMNHQKCCSEA
What is the function of this protein?
(Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells.
What are the official names of this protein?
Neuropilin-2, Vascular endothelial cell growth factor 165 receptor 2.
What is the protein family that this protein belongs to?
Belongs to the neuropilin family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform s9]: Secreted.
Protein: GSA_BURM7
Sequence: MSNNQTLFERAQRTIPGGVNSPVRAFRSVGGTPRFVARAQGAYFWDADGKRYIDYIGSWGPMIVGHVHPDVLAAVQRVLADGFSFGAPTEAEIEIAEEICKLVPSIEQVRMVSSGTEATMSALRLARGFTGRSRIVKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPADVAKHTTVLEYNNVAALEEAFAAFGGEIAAVIVEPVAGNMNLVRGTPEFLNALRALTAKHGAVLIFDEVMCGFRVALGGAQQHYGITPDLTCLGKVIGGGMPAAAFGGRGDIMSHLAPLGGVYQAGTLSGNPVAVAAGLATLRLIQAPGFHDALADKTRRLADGLAAEARAAGVPFSADAIGGMFGLYFTEQVPASFADVTKSDIERFNRFFHLMLDAGVYFAPSAYEAGFVSSAHDDATLDATLDAARRAFAALRA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDM_HUMAN
Sequence: MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSSHLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLWVVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGSIRIHNAELQRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
What are the official names of this protein?
Aspartate--tRNA ligase, mitochondrial, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.