PharMolix/UniProtQA huggingface dataset:
Protein: RNC_HUMAN
Sequence: MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
What is the function of this protein?
Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis.  Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus.  Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.  Involved also in pre-rRNA processing.  Cleaves double-strand RNA and does not cleave single-strand RNA.  Involved in the formation of GW bodies.
What are the official names of this protein?
Ribonuclease 3, Protein Drosha, Ribonuclease III, RNase III, p241.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=A fraction is translocated to the nucleolus during the S phase of the cell cycle. Localized in GW bodies (GWBs), also known as P-bodies.
Protein: KDSA_ACISJ
Sequence: MQLCGFDVGLDQRFFLIAGTCSIEGLEMSLDVAGQLKEACAPLGIPLIYKGSFDKANRSSGTSKRGVGLDAGLKILDEVRRQLQLPILTDVHDTSHVAEVASVVDVLQTPAFLCRQTDFIRAVAQSGKPVNIKKGQFLAPWDMKNVIDKARAAAREVGLSEDRFLACERGVSFGYNNLVADMTSLAEMRNSGAPVVFDVTHSVQKPGGLGAVSGGARDMVPVLARAGVAVGVAGLFMETHPKPAEAWSDGPNAVPLKHMRALLETLVALDDVTKKNGFLENNFGA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_STRP2
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGMVAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSHRRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNIIVLAEGVMSAAEFGQKLKEAGDISDLRVTELGHIQRGGSPTPRDRVLASRMGAHAVKLLKEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHEADIELSSLNKSLS
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIC1_TOXGO
Sequence: MGQALFLTVLLPVLFGVGPEAYGEASHSHSPASGRYIQQMLDQRCQEIAAELCQSGLRKMCVPSSRIVARNAVGITHQNTLQWRCFDTASLLESNQENNGVNCVDDCGHTIPCPGGVHRQNSNHATRHEILSKLVEEGVQRFCSPYQASANKYCNDKFPGTIARRSKGFGNNVEVAWRCYEKASLLYSVYAECASNCGTTWYCPGGRRGTSTELDKRHYTEEEGIRQAIGSVDSPCSEVEVCLPKDENPPLCLDESGQISRTGGGPPSQPPEMQQPADRSDERGGGKEQSPGGEAQPDHPTKGGNIDLPEKSTSPEKTPKTEIHGDSTKATLEEGQQLTLTFISTKLDVAVGSCHSLVANFLDGFLKFQTGSNSAFDVVEVEEPAGPAVLTIGLGHKGRLAVVLDYTRLNAALGSAAYVVEDSGCSSSEEVSFQGVGSGATLVVTTLGESPTAVSA
What is the function of this protein?
Adhesin.  Required for attachment of the parasite to the host cell prior to invasion.  Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes.
What are the official names of this protein?
Micronemal protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, microneme.
Protein: ARGA_ACTPJ
Sequence: MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDISLLHSLGIKLVIVFGARCQIDELLAKNQMSSTYHKHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLNVVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQDAIVVIGPIAPSVTGEMFNLPFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSAARFLQASIEVCHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIPGLLNLIRPLEEQGILVKRSREQLEMEISNYTIIERDGIVIACAALNHYPEEKMAEMACVAVHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQWFQERGFVLSTTDDLPKEKREHYNYQRMSKILILELSQ
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST5A_HUMAN
Sequence: MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP
What is the function of this protein?
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.
What are the official names of this protein?
Carboxylesterase 5A, Carboxylesterase-like urinary excreted protein homolog, Cauxin.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GHOS_ECO57
Sequence: MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEYGIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK
What is the function of this protein?
Antitoxin component of a type V toxin-antitoxin (TA) system.  Neutralizes the toxic effects of toxin GhoT by digesting ghoT transcripts in a sequence-specific manner.  In concert with GhoT is involved in reducing cell growth during antibacterial stress.
What are the official names of this protein?
Endoribonuclease antitoxin GhoS, Antitoxin GhoS.
Protein: H10_RAT
Sequence: MTENSTSTPAAKPKRAKAAKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKGDEPKRSVAFKKTKKEVKKVATPKKAAKPKKAASKAPSKKPKATPVKKAKKKPAATPKKAKKPKIVKVKPVKASKPKKAKPVKPKAKSSAKRASKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.  The histones H1. 0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
What are the official names of this protein?
Histone H1.0, Histone H1', Histone H1(0).
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RFA3_TETTS
Sequence: MDAEQEQVMYPRILFEQMAQFRGKKVTVVGNVCNEDQNDSLVIEFGPTGLNQHVVIDNYRRVDLNNTTKFVEIRGVVLNQNIVSCEELTEFEQKDPFDFDTYSKLIHLSQSDKLSSLFTDQ
What is the function of this protein?
Component of the heterotrimeric replication protein A (RPA) and holoenzyme telomerase ribonucleoprotein complexes (PubMed:26472759, PubMed:27895115).  As part of the heterotrimeric RPA complex, binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress (By similarity).  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism (By similarity).  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (By similarity).  In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation (By similarity).  Also part of a subcomplex of the holoenzyme telomerase ribonucleoprotein complex: this subcomplex that contains TEB1, RPA2/TEB2, RPA3/TEB3, but not RPA1, mediates the recruitment of telomerase to telomeric DNA via specific interaction between TEB1 and telomeric ssDNA (PubMed:27895115).  In the holoenzyme telomerase ribonucleoprotein complex, RPA2/TEB2 and RPA3/TEB3 act as assembly factors for TEB1 incorporation into telomerase holoenzyme (PubMed:27895115).  In the holoenzyme telomerase ribonucleoprotein complex, RPA3/TEB3 does not contribute to ssDNA affinity, while it contributes to ssDNA affinity in the RPA complex (PubMed:27895115).
What are the official names of this protein?
Replication protein A 14 kDa subunit, RP-A p14, Replication factor A protein 3, RF-A protein 3, Telomeric repeat-binding subunit 3.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RBFA_LISMF
Sequence: MNVRANRVSEQMKKELGDILNRKIKDPRLGFVTVTGVDVTGDLQEAKVFISILGTDKEKENTLLALAKAHGFIRSEIGRRIRLRKVPEMSFEIDNSIAYGNRIDELLRDLNNDQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPIN1_CHICK
Sequence: MGEYGIAPGQRVAVIWDSSSPVEALKGLVDAVQASVGADSRVSVENINQLCQSAHRESSFDVILSGVVPGSTAQHSAEVLAEIARILKPGGRVLLKEPVVTESENNSQIKTAAKLPAALTLSGLVEVKGLQKEPLTAEEAQSVREHLGYQGNDLLIVQIEGRKPNFEVGSSSQLKLSFAKKTSPSGKPSVDPATAKLWTLSASDMNDEEMDLLDSDELLDSEDLKKPDPASLRAPSCKEKGKKKACKNCTCGLAEELEQEKKSSQPKSACGNCYLGDAFRCASCPYLGDACLQAWREDPAEREPAA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.  Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1.  NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.  Has anti-apoptotic effects in the cell.  Involved in negative control of cell death upon cytokine withdrawal.  Promotes development of hematopoietic cells.
What are the official names of this protein?
Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: RS10_RUEST
Sequence: MQSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRGPHVDKKSRDQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLQS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CHL1_ASPNC
Sequence: MELQRNDFHHPYSPYDIQLQLMRALYSCLEQGKVAVFESPTGTGKSLSLICGSLTWLRDHKRSAFQTAVDNATCDDDEPEWMLDFARRESSRMMTEKRKELEERLEKTRKEEEQQRIALENPEGPRKKQKYSIPLTESGGLSEDQFALDDYDSENEEHSKPRDELAHTSELSPSTLELLERFKGQISTAKPGSDDADNDEVKIFYCSRTHSQLTQFAGELRRVKMPWSIPKDLLSTDLTGEEELEERVKHVTLGSRKNLCINPRVSSLENATAINERCLDLQQPNVNPQHRCPFLPSKEDERQVLQFRDHALSTVKDIEDLGKLGKKIGICPYYASRSVVKDSEVCCLRARSSIDLVPDEWQIVTLPYPLLLQRSAREALNSSVKGHVIIIDEAHNLMDAISNIHSVTVTLSQLQTSLSQLTIYGRKFKTRLKGKNRSYVAQVIRLLSSIAAHLRSLLESGKAPEGPVLISELMSGKGVDQINPYKLSRYLQESKLARKVDGYVEFTRDPSDKQASRSPTVPVLFHIQGFLLSLMNPSAEGRLFYSKEQGDIQLKYMLLDPTNQFRELVEDARAIILAGGTMSPMTDYMNHLFSYVPASRLDTFSYGHVIPPENLIAHTLVRGVQGSEFDFTYDARDSEKMIMDLGRTIATLCHVIPDGVVAFFPSYDYLGRVLNIWKKPMLGEQGQTVYNLIGQKKPILSESRDMTVTTEELLHTYANTVDSGRGALLLSVVGGKLSEGINFSDKLGRGVLIVGLPFPNIRSAVWQAKIQYIEQKTHQQATGSEASRQLAAKAAGRDFYENSCMRAVNQCIGRAIRHRNDYAAIVLVDRRYEKPGIQAKLPAWIKQSMVGSSVQRPAGATVQSLAKFFASKST
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase chl1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCDA_BACMT
Sequence: MYFHGTTKVNEKGHLEIGGVDTIELAQKYGTPLYVYDVALIRERARGFKNTFDELGIKAQVAYASKAFSTVAMIQLAEEEGLSLDVVSGGELYTALVAGFPVHKIHFHGNNKSRAELEMALEHQIGCIVVDNFHELDLIDSICSEKNVKTNILLRVTPGIEAHTHDYILTGQEDSKFGFDLQNGQAEKALQIALNSNFVEVLGVHCHIGSQIFDTTGFVLAARKIFEKLKEWKDRLSYEPKVLNLGGGFGIRYTEEDDPIPASQYVKEIINEVKKQVSAYSMKMPEIWIEPGRSLVGDAGTTLYQIGSRKDVPNVRHYVAVDGGMSDNIRPALYNAKYEAVLANKPLAKADETVSIAGKCCESGDMLIWDLPLPKADSDDILAVFCTGAYGYSMANNYNRIPRPAVVFVENGESMLVVKRKHMRTSSAMICL
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: PSA5_BOVIN
Sequence: MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: T23O_BURMS
Sequence: MQPPGDDAAPRCPFAGAHAPDAPHVPEAAGDDVQAGWHRAQLDFSQSMSYGDYLSLDPILDAQHPRSPDHNEMLFIIQHQTSELWMKLALYELRAALASIRDDALPPAFKMLARVSRVLEQLVQAWNVLATMTPSEYSAMRPYLGASSGFQSYQYRELEFILGNKNAQMLRPHAHRPAIHAHLEASLQAPSLYDEVIRLLARRGFPIAPERLDADWTQPTRHDRTVETAWLAVYREPNAHWELYEMAEELVDLEDAFRQWRFRHVTTVERIIGFKQGTGSTSGAPYLRKMLDVVLFPELWHVRTTL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: YYDK_BACSU
Sequence: MLKYQQIATEIETYIEEHQLQQGDKLPVLETLMAQFEVSKSTITKSLELLEQKGAIFQVRGSGIFVRKHKRKGYISLLSNQGFKKDLEDFNVTSKVIELDVRKPTPEAAENLNIGMDEDIYYVKRVRYINGQTLCYEESYYTKSIVTYLNNEIVSHSIFHYIREGLGLKIGFSDLFLHVGQLNEEEAEYLGLEAGLPKLYIESIFHLTNGQPFDYSKISYNYEQSQFVVQANSFLL
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YydK.
Protein: DRNG_AERHY
Sequence: MFRPLLSFTLARLVSLPLHAQTFRAAKQDLNRLYQDHPVTFYCGCKIEYQGKKMSPDLASCGYEPRKQAKRANRIEWEHVVPAWEFGHQLQCWQQGGRKNCGKTDEFNQMEGDMHNLFPAIGEVNVDRANYRFSDWNGTPHQYGQCQMLVDFKERQVQPPKGLVRGQIARAYLYMSQQYGPGLAAQQRKLFEAWDRQYPADGWECERNRRIGKLQGNTNPFIEKQCQ
What are the official names of this protein?
Extracellular deoxyribonuclease, DNase.
What is the protein family that this protein belongs to?
Belongs to the EndA/NucM nuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPP40_RAT
Sequence: MATLRRLQEAPRHLLVCEKSNFGHDKSRHKHLVETHYHNYRVSFLIPECGLLSKKLKDLVMEMGPYYSVKKLPLHELITHEFINTFVKKGSLSALTYNTSIDEDNTVALLPNGKLILSLDKDTYEETGLQGHPSRYSGRKSMRFIISIDLMDLSLNLDSKKYRRISWSFKEKKPLKFDFLLAWHHTGTEESTMMSYFSKYQIREHQPKVALSTVRDLQCPVLQSSSLAGEPEEACNALEFFDWLGAVFCNADLNNEPHNFISTYCCPQPNTVAAQACLCTITGFVLPEKILVLLEQLCHYFDEPKLAPWVTLTVQGFADSPVAWREKEHGFHKGGEHLYNFVVFNNQDYWLQMAVGANDDCPP
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonuclease P protein subunit p40, RNaseP protein p40.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TRMD_BARBK
Sequence: MTFQAHVVTLYPEMFPGVLGHSLAGRALERGIWSLNTVQIRDFALDKHHSVDDTPAGGGAGMVMRADVLVAAIDHCPPDLPRILLSPRGRPFNQAHARSLASDRGVVLVCGRFEGVDERVLQARKLEEISIGDYILSGGETAALVLLDALVRLLPGVMGNQASGECESFENGLLEHPHYTRPPVFEGLEIPLVLTSGHHKAIADWRQEQAEMLTQKRRPDLYAIYNKNRRKT
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_CORDI
Sequence: MIDLKLLRENPDVVRESQRIRGEDPALVDQLLEADEKRREAIKSADDLRAEHKAFGKKISQASPEERPALLEGSNELKSRVKAAEEAEAEALAKVNEIQMLFGNVVTDAPAGGEDDYIVLEHVGTPRTFDFEPKDHLDLGESLGLIDVKRGTKVGGARFYYLTGDGAFLQLGMLNLAAQKARENGFQLMIPPVLVRPEVMSGTGFLGAHSDEIYYLERDDLYLVGTSEVALAGYHQDEIIDLSDGPIKYAGWSSCFRREAGSYGKDTRGILRVHQFDKLEMFVYCKPEEAVAQHQALLNMEREMLAAVEVPYRIIDVAGGDLGSSAARKFDTEAWIPTQNTYRELTSTSNCTTFQARRLRTRYRDESGKAHTAATLNGTLATTRWLVAILENNQQADGSVIVPEALRPFVGKEVLEPKK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR14_IPOPU
Sequence: MARKSLIQREKKRQKLEMKYHLIRRSSKKEISKVALLSDKWEFYGKLQSPPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILREMVQACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTH_STAAM
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKGAYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEKVIEHAARAIEKFVETSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1559_ARATH
Sequence: MELDLSVLGRSFIVTRRNSSITRPCIQSSNFSVRVLQRNKHRPLCFSTNPSNSSFIRFQKGCDFSHRCQFVVLSATGDHVGISQKHSDSTEKVDSIRILLKRGIVLGAVVCGVLFYGCGKVLASTSVVDVAFSKSILLLKNAWPKTSQVLKVLREQGLILAVLLGLSAFFSMAETSITTLWPWKVRELAEKEPENGVFRMLRSDVTRFLTTILIGTTVVNIAATALVTKAATAIFGEAGVSAATGVMTVAILLLTEITPKSVAVHNAQEVARIVVRPVAWLSLILYPVGRVVTYLSMGILKILGLKGRSEPYVTEDELKLMLRGAELSGAIEEEEQDMIENVLEIKDTHVREVMTPLVDVVAIDGSGSLVDFHNFWVTHQYSRVPVFEQRIDNIVGIAYAMDLLDYVPKGKLLESTTVVDMAHKPAFFVPDSMSVWNLLREFRIRKVHMAVVLNEYGGTIGIVTLEDVVEEIVGEIFDENDSKEEIQKKTGYIVMRAEGIYDVDANTSIDQLSEELNIKMAEGHQYETVSGFVCEAFGYIPKTGESVTVVLEKENWEENDEQDEGKHERQDQKEKHQIYRLEILAGNARKVSAVRFERVSDMDQVSEARDVKNMVPKFVRKWSSEEDSDGNLQAKNAVFDEHLIAETESMKKE
What are the official names of this protein?
DUF21 domain-containing protein At1g55930, chloroplastic, CBS domain-containing protein CBSDUFCH2.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: LPXC_RALSO
Sequence: MLKQRTIKSVVKTVGIGLHSGRKVTLTLRPAAPGNGIIFTRVDLDPAVEIPATASAIGDTRLASVLQKDGARVSTVEHLMSACAGLGIDNLYVDVDAEEIPIMDGSAASFVFLLQSAGIEEQGAAKRFIRVIKPVEVRDGDKLARLEPYFGFKLSFTIEFRHPAVDKTGQTFEIDFADTSYTREIARARTFGFAHEVEMLREIGLARGGSLDNAIVLDEHRMLNNDELRYGDEFVRHKILDAIGDLYVVGYPLIAAYTAHKSGHGLNNALLRALLADEAAYEIVTFDKVEEAPRAFLPQLQPAFS
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PYRB_WOLPM
Sequence: MNKRRNLLNISDLTVDDVENITKLANQYLKKEVANSHILENKTVINLFFEDSTRTLASFEIAAKSLGANVVTLPIRSSSINKGEDLKDMIKTLNAMNPDYIIIRHKSSGIINTLAKYVNCSLINAGDGSSEHPTQALADYLVISNHKKQIKDLKVVICGDILHSRVARSNIRLLKMFGAEINLVAPPTLICKHFPEVDSVHYSLIEGIKDADVIMLLRLQKERMNNSSSEKEYFYLYGLDSQKLSYAKPDAIVMHPGPINRGIEISSDVADCVILQQVEFGLAIRKAVLHYYRPC
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.