PharMolix/UniProtQA huggingface dataset:
Protein: EUPE_PHOSX
Sequence: MKEIWETLKQYFGDGFVPGSAPLRYEMHFCDMKEPLNKKQSMRYGVEIPEDAMPLFSVLGDTCAPPCSCQDISGVIEHIDRYLENAPIRHADDYTITSGKDDEDINQVSLYIMRDTLSWWVHWGGSLHPNNYWKLIYVAFAAIPDDVQVHPRDFIDGTYRFLGHSWNDCLNGLLAEGVPSDQVKLAEMTLWRQMATQYIEKVDPGLRSLLVSKTTLMTQYRVMTANTLGCAVLLLASEGVIVGDLDDGALEMASIAQCLSMDMAKEALGVLEGEKTETVAGDRRQLKRELRWLYVRCMKYLDAQPHAEFLRRFASSGLHYVPMMDRYLERVRGHIRFPIRESVARILEPFIKREPTPNKSGREADHIAQVVNEPITVAL
What is the function of this protein?
Alpha-humulene synthase; part of the gene cluster that mediates the biosynthesis of eupenifeldin, a bistropolone meroterpenoid that acts as an antitumor agent (PubMed:30980906).  The first step of eupenifeldin biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase eupA (PubMed:30980906).  Oxidative dearomatization of 3-methylorcinaldehyde likely catalyzed by the FAD-dependent monooxygenase eupB is followed by oxidative ring expansion by the 2-oxoglutarate-dependent dioxygenase eupC to provide the first tropolone metabolite, tropolone stipitaldehyde (Probable).  In parallel, generation of sesquiterpene alpha-humulene from farnesylpyrophosphate (FPP) is catalyzed by the terpene cyclase eupE (PubMed:30980906).  The cytochrome P450 monooxygenase eupD then hydroxylates humulene to humulenol (PubMed:30980906).  The putative Diels-Alderase eupF probably catalyzes the formation of the tropolone-humulene skeleton by linking humulenol and the polyketide moiety (Probable).  The short-chain dehydrogenase/reductase eupG and the flavin-dependent monooxygenase eupH are also essential for eupenifeldin biosynthesis and are likely the additional decorating enzymes of the tropolone-humulene skeleton to produce final eupenifeldin or derivatives (Probable).
What are the official names of this protein?
Alpha-humulene synthase eupE, Eupenifeldin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Alpha-humulene synthase eupE subfamily.
Protein: THIK_SALPA
Sequence: MRSNNNNPLTRDEILSRYFPQYRPAVTASQGLSGGSCIIAHDTHRIVLRRHHDPDAPPAHFLRHHRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDADELAALLYHLHQQPHFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: CC74B_HUMAN
Sequence: MSGAGVAAGTRPPSSPTPGSRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQHSEMLAKLHEEIEHLKRENKDLRYKLIMNQTSQKKDGPSGNHLSRASAPLGARWVCINGVWVEPGGPSPARLKEGSSRTHRPGGKHGRLAGGSADTVRSPADSLSTSSFQSVKSISNSGKARPQPGSFNKQDSKADVPQKADLEEEPLLHNSKLDKVPGVQGQARKEKAEASNAGAACMGNSQHQGRQMGAAAHPPMILPLPLRKPTTLRQCEVLIRELWNTNLLQTQELQHLKSLLEGSQRPQAVPEEASFPRDQEATHFPKVSTKSLSKKCLLLSPPVAERAILPALKQTPKNNFAERQKRLQAMQKRRLHRSVL
What are the official names of this protein?
Coiled-coil domain-containing protein 74B.
Protein: RS4_VIBC1
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGVHGARRGRLSEYGVQLREKQKVRRMYGVLEKQFRNYYKEAARLKGNTGENLLQLLEGRLDNVVYRMGFGATRAEARQLVSHKAILVNGKVVNVPSFKVAANDVVSIREKAKQQARIKAALEVAEQREKPTWIEVDGGKMEGTFKRMPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NADA_SALTY
Sequence: MSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGTKHAASTLLVAGVRFMGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPDAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFAATLRA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_RICRS
Sequence: MVDLKTKAFDISQNFTIALDGPAASGKGTIGLILAKKFSLKYFQSSIVYRQLAFDCISQKIDVTDIDAVIALSKELKLDNNFDLENENIGNIASQIAVISEIRNNLNKYLINLVKTTPRMIMEGRDIGTVVAPDADLKIFITANPQIRAERRYKQLQAKGKTCILAEILQQIILRDKRDKERKAAPLLPASDALIIDTSKLSAMEVVEEVTNYIKNKIT
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_CLOBH
Sequence: MLERLNFIENKYEELSNKISDPSVMANQKEWQKLCKEHADLEIIVNTYREYKKAQEDLESDKEMLKEESDKELREMAQEEIKELTLKLEDLERELTILLLPKDPNDDKDVFIEIRAGAGGEEAALFASNLLRMYTRYAERKNWKVETISLNATDIGGFKEVTVAVKGKGAYSRLKYESGVHRVQRVPDTESSGRIHTSTATVAVLPEVDDVDININANDLRIDVYRASGHGGQCVNTTDSAVRITHLPTGLVVTCQDEKSQLKNKEKAMKVLKARLFEAAEAERAASIAEDRKSQVGTGDRSERIRTYNYPQGRITDHRIGLTLYKLETFLDGDIDEAIEALVTEDQAEKMKDLGRVN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_FRATH
Sequence: MSYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISAGKQGLLTGIPILHKDLFCTKGIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMDEFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAGFAPISTGSDTGGSVRQPASFCGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQNHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEALSTYYIITPAEAAANLARYDGIRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVLASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPSEAFKKGDKLDPVSAYLSDIYTIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQARI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PSBH_OSTTA
Sequence: MAAKDSKLAGTGKVTALGTALRPLNSEYGKVAPGWGTTILMSVFIGLFAVFIVILLEIYNKSLILDNVGVNWLSSTGL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CIF_BURPS
Sequence: MLEHGVMKIPGINNVGKTGQAGGETERIPSTEPLGSSAATSPAGPLGGLPARSSSISNTNRTGENPMITPIISSNLGLKHRVTLRKATLASLMQSLSGESSNRVMWNDRYDTLLIARDPREIKNAIEKSVTDFGGLENYKELTGGADPFALMTPVCGLSANNIFKLMTEKDVPIDPTSIEYLENTSFAEHVNTLDSHKNYVVIVNDGRLGHKFLIDLPALTQGPRTAYIIQSDLGGGALPAVRVEDWISRRGSDPVSLDELNQLLSKDFSKMPDDVQTRLLASILQIDKDPHKVDIKKLHLDGKLRFASHEYDFRQFQRNAQYVAGLG
What is the function of this protein?
Protein-glutamine deamidase effector that inhibits the host cell cycle and other key cellular processes such as the actin network and programmed-cell death (PubMed:19308257, PubMed:20688984, PubMed:19225106).  Acts by mediating the side chain deamidation of 'Gln-40' of host NEDD8, converting it to glutamate, thereby abolishing the activity of cullin-RING-based E3 ubiquitin-protein ligase complexes (CRL complexes) (PubMed:20688984, PubMed:21903097).  Inactivation of CRL complexes prevents ubiquitination and subsequent degradation of the cyclin-dependent kinase inhibitors CDKN1A/p21 and CDKN1B/p27, leading to G1 and G2 cell cycle arrests in host cells (PubMed:19308257).  Deamidation of 'Gln-40' of host NEDD8 also triggers macrophage-specific programmed cell death (PubMed:23175788).  Also able to catalyze deamidation of 'Gln-40' of host ubiquitin in vitro; however, NEDD8 constitutes the preferred substrate in vivo (PubMed:20688984).  Also regulates the host NF-kappa-B signaling via activation of MAPK/ERK cascade: activation of host MAPK/ERK cascade is independent of CRL complexes inhibition, suggesting that Cif has other host protein targets than NEDD8 (PubMed:28166272, PubMed:29848489).
What are the official names of this protein?
Protein-glutamine deamidase Cif, Cycle-inhibiting factor homolog, CHBP.
What is the protein family that this protein belongs to?
Belongs to the Cif family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Secreted via the type III secretion system (TTSS).
Protein: RAA4B_ARATH
Sequence: MAGGGGYGGASGKVDYVFKVVLIGDSAVGKSQLLARFARDEFSMDSKATIGVEFQTRTLSIEQKSIKAQIWDTAGQERYRAVTSAYYRGAVGAMLVYDMTKRETFEHIPRWLEELRAHADKNIVIILIGNKSDLEDQRAVPTEDAKEFAEKEGLFFLETSALNATNVENSFNTLMTQIYNTVNKKNLASEGDSNNPGSLAGKKILIPGSGQEIPAKTSTCCTSS
What is the function of this protein?
Regulator of membrane trafficking.  May be required for secretion of cell wall components in cells.
What are the official names of this protein?
Ras-related protein RABA4b, AtRABA4b, Ras-related protein GB3, AtGB3, Ras-related protein Rab11G, AtRab11G.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Early endosome membrane. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor.
Protein: COPE_PONAB
Sequence: MAPPAPGPTSGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPETDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
What are the official names of this protein?
Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP.
What is the protein family that this protein belongs to?
Belongs to the COPE family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: S22AF_MOUSE
Sequence: MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSHSNQTLGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRKLKCTFSLTHPANRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLDKVSSESEEEEEFYDADEETQMIK
What is the function of this protein?
Probably transports organic cations.  Appears not to be the agmatine transporter.
What are the official names of this protein?
Solute carrier family 22 member 15.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YFH7_VANPO
Sequence: MFDIDGLVSDSLKLLADRVDKNYRISLVIVGPPGSGKSTIANELCERLNSMFHEYLKEHGGNIEISGVSEPLPVDITEPIREVSRNIVEYMTSNDGILPQSVEDLDFECVKFQDDGRDNGNVNGNVKVIGRGGLPNAIEVSPYHDLSKPKEKCDVNIAQIIPMDGFHLTRKCLDNFKDPVNAHRRRGSPSTFDSNNFLQLCKLLAETSNTKIPLSRFQNSDNDDVDAVWEKLAKTFTSDVQDIYIPGFDHSLKDPTSNQYCINGFTRIMIFEGLYLLYDQENWSKIYQVLSGTDALLIWNIDIDEAVIQDRVAKRHLNSGLVNTFEEGIDKFQVNDLLNARSIRQHTLDVKDVVTIHND
What is the function of this protein?
ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.
What are the official names of this protein?
ATP-dependent kinase YFH7.
What is the protein family that this protein belongs to?
Belongs to the YFH7 family.
Protein: MYO1_KLULA
Sequence: MALIRRAKNKVAPQKRAETTIKKATFDATKKKEVGVSDLTLLSSISDDAINQNLKKRFENGTIYTYIGHVLISVNPFRDLGIYTDAVLESYKGKNRLEVPPHVFAIAEAMYYNLKAYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHEASIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIRFNEQFEPCAGQITNYLLEKQRVVGQIRNERNFHIFYQFTKGASDTYRQNFGVLQPDQYIYTSASGCTSVDTIDDLHDYQETIKAMQVIGLSQEEQDQIFRMLSAILWIGNVTFVENNEGNAEVRDTSVTDFVAYLMQVDSGLLIKCLVERVMETGHGSRRGSVYHVPLNVVQATAVRDALAKAIYNNLFDWIVDRVNVSLKAFPGAVKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQEEYNKEQIQWTPIKYFDNKVVCDLIESKRPPGIFATLDDSVATAHADSNAADQAFAQRLNLFSTNAHFDLRSSKFVIKHYAGDVTYDISGMTDKNKDQLVKDLAELVQTTTNPFLSTIFPDTIDKSSKRRPPTAGNKIIKSANELVETLSKAQPSYIRTIKPNQTKSPRDYDDQQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPKCSYAGDYTWQGDTLGAVKQILQDASIPTTEYQLGVTKVFIKTPETLFALEHMRDRYWYNMAARIQRAWRRFIQRRIDSAIKIQRAIREKKGGNQYEQLRDYGHRLLGGRKERRAMSLLGYRAFMGDYLSCNEMKSKGAFIKRQAGISEIVVFSIKGEALHSKFGRSAVRLPITIILTPTTLYIVGQTVAQNQVSYTVDRKVNISHIKHVSLTNLADDWVGIYVQGENLPDPFINTIFKTELITHLKQLNRAIEVKIGPTIEYQKKPGKLHTVKCQISESAPKYSDIYKSSTISVRQGRPANSRQAPKPEKKSTLLSDGPSYNSNQSKGYGQQQHAQPSYGQQQQQQQRYAPQSHATPQTTQKKRAPPPPGQQNFAASAAQTAYHPQQASHARVPSTNNAHTQHNRQPAQQAAQPVQQAAQPAATTSQPTRRVAPPPPPPPPTKQNIPKFQAAYDFTGTGSASELPLSKGTVITVSKQDPSGWSLGKLLDGSKEGWVPTNYIVEYKESSGPPPPPAPPVASSTTGYANSNNNAFAANDNVAAVAGAAAGATAGAAVAAASLANPGQNAFSVGLADALAARANTMRLESDDESTGNADEDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: TEAD1_MOUSE
Sequence: MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD
What is the function of this protein?
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.  Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner.  The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF).  Involved in cardiac development.  Binds to the M-CAT motif (By similarity).
What are the official names of this protein?
Transcriptional enhancer factor TEF-1, NTEF-1, Protein GT-IIC, TEA domain family member 1, TEAD-1, Transcription factor 13, TCF-13.
What are the subcellular locations of this protein?
Nucleus.
Protein: CEP1_ARATH
Sequence: MKRFIVLALCMLMVLETTKGLDFHNKDVESENSLWELYERWRSHHTVARSLEEKAKRFNVFKHNVKHIHETNKKDKSYKLKLNKFGDMTSEEFRRTYAGSNIKHHRMFQGEKKATKSFMYANVNTLPTSVDWRKNGAVTPVKNQGQCGSCWAFSTVVAVEGINQIRTKKLTSLSEQELVDCDTNQNQGCNGGLMDLAFEFIKEKGGLTSELVYPYKASDETCDTNKENAPVVSIDGHEDVPKNSEDDLMKAVANQPVSVAIDAGGSDFQFYSEGVFTGRCGTELNHGVAVVGYGTTIDGTKYWIVKNSWGEEWGEKGYIRMQRGIRHKEGLCGIAMEASYPLKNSNTNPSRLSLDSLKDEL
What is the function of this protein?
Possesses protease activity in vitro (PubMed:25035401).  Involved in the final stage of developmental programmed cell death and in intercalation of new cells.  Cleaves extensins, thus probably supporting the final cell collapse (PubMed:21632425).  During the compatible interaction with the biotrophic powdery mildew fungus Erysiphe cruciferarum, involved in the control of late epidermal cell death that limits growth and susceptibility to the parasite (PubMed:24605116).  During anther development, involved in tapetal programmed cell death (PCD), leading to degeneration of tapetal cells and functional pollen formation (PubMed:25035401).
What are the official names of this protein?
KDEL-tailed cysteine endopeptidase CEP1, Cysteine proteinase CP56, AtCP56.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Vacuole. Note=During anther development, detected as a proenzyme in precursor protease vesicles in tapetum cells and then transported to the vacuole and transformed into the mature enzyme before rupture of the vacuole.
Protein: TRA9_MYCTA
Sequence: MPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Putative transposase for insertion sequence element IS986/IS6110, ORFB.
Protein: TPIS_PSEF5
Sequence: MRRPMVAGNWKMHGTRASVAELINGLRHLALPSGVDVAVFPPCLYINQVIDGLKGKSIQVGAQNSAVESMQGALTGEIAPSQLVDAGCSLVLVGHSERRLIMGERDATLNRKFAAAQACGLKPVLCVGETLEQREAGKTLEVVGRQLGSIIEELGVGAFANAVIAYEPVWAIGTGLTATPQQAQDVHAAIRAQLAAENSEVARGVRLLYGGSVKAANAVELFGMPDIDGGLIGGASLNADEFGAICRAAGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LG31_VIGUS
Sequence: ANQTYFNFQRFEETN
What is the function of this protein?
Trypsin-stable lectin with hemagglutinating activity.  Has mitogenic activity on murine splenocytes.  Inhibits HIV-reverse transcriptase.
What are the official names of this protein?
Lectin 31 kDa subunit, Hemagglutinin 31 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: GP42_EBVG
Sequence: MVSFKQVRVPLFTAIALVIVLLLAYFLPPRVRGGGRVAAAAITWVPKPNVEVWPVDPPPPVNFNKTAEQEYGDKEVKLPHWTPTLHTFQVPQNYTKANCTYCNTREYTFSYKGCCFYFTKKKHTWNGCFQACAELYPCTYFYGPTPDILPVVTRNLNAIESLWVGVYRVGEGNWTSLDGGTFKVYQIFGSHCTYVSKFSTVPVSHHECSFLKPCLCVSQRSNS
What is the function of this protein?
Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes.  May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells (By similarity).
What are the official names of this protein?
Glycoprotein 42, gp42.
What is the protein family that this protein belongs to?
Belongs to the epstein barr virus gp42 family.
What are the subcellular locations of this protein?
Virion membrane. Note=virions synthesized in B- lymphocytes contain a lower amount of gp42 due to sequestration by cellular HLA class II protein, whereas virions made from epithelial cells has a higher amount of gp42. Membrane; Single-pass membrane protein (By similarity).
Protein: THII_SHEB2
Sequence: MKFIVKLYPEIMMKSKPVRMRFTKMLETNIRNVLKKVDEDAKVQRQWDRIMVMVPKDKPELAQAFGERLACIPGIAHVVQVDEYSFESVDDIYQQVLPVYRDQLAGKTFCVRVKRTGDHDFNSIEVERYVGGGLNQFTDALGVRLKNPDITVNLEIERDNLYMVTKRIEGLGGFPMATQEDVLSLISGGFDSGVSSYQFIKKGARTHYCFFNLGGAQHEIGVKQVAYHLWKTYGESHKVKFISVPFEPVVAEILERIDNGQMGVVLKRMMMRTAARIADRMGIQALVTGESLGQVSSQTLTNLNVIDRCTELLILRPLIAMDKQDIINESRKIGTEDFAKSMPEYCGVISQKPTVKAVLAKVEAEEKKFSEDLIDQIIAQSVTIDIREIAEQMDTRITETETVASIDTNQVVIDIRAPEEEESKPLQIEGIEIKRIPFFKLATQFADLDKQKTYLLYCERGVMSKLQALYLIEQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5HT5A_MOUSE
Sequence: MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFGWGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVSPVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  The activity of this receptor is mediated by G proteins.
What are the official names of this protein?
5-hydroxytryptamine receptor 5A, 5-HT-5, 5-HT-5A, 5-HT5A, Serotonin receptor 5A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.