PharMolix/UniProtQA huggingface dataset:
Protein: CATB_ASPOR
Sequence: MRALSLASLIGIASAACPYMTGELERRDTGTDDATAATEEFLSQYYMADNDTFLTSDVGGPIEDQNSLQVGDRGPTLLEDFIFRQKIQRFDHERVPERAVHARGVGAHGVFTSYGDYSNITAASFLGAEGKETPVFVRFSTVAGSRGSSDLARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAILFPDLIHAVKPRGDNEIPQAATAHDSAWDFFSQQPSSLHTLLWAMSGHGIPRSLRHVDGFGIHTFRFVTDNGDSKLVKFHWKSLQGKASMVWEEAQQVSGKNPDFMRQDLFEAIEAGRYPEWELGVQIMDEEDQLKFGFDLFDPTKIVPEEYVPITKLGKMTLNRNPRNYFAETEQVMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLNRHGGPNFEQLPINQPRVPVHNNNRDGAGQMFIPLNPNAYSPNTLNKGSPKQANQTVGKGFFTAPGRESTGRFTRAVSPSFEDVWSQPRLFYNSLTPAEQQFVVDAIRFENSNVKSSVVRNNVIIQLNRVSNDLARRVARAIGVEEPEADPTYYHNNKTTDVGTFGQKLKKLDGLKVGFLASVETPASIEAASELSKQLSEDGVDVVVVAERLSDGVDQTYSGSDAIQFDAVIVAPGAEGLFSTFSFTAPSNATSSSTLFPAGRPLQIVIDGFRFGKPVGAVGSAATALKNAGIQTSRDGVYVDKSVTSGFVDGIKDGLRTFKFLDRFKLDH
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide through its degradation into water and oxygen.
What are the official names of this protein?
Catalase B.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMA_XANAC
Sequence: MSTPRIVVGVSGGVDSSVAAWKLAQQGEPIAGLFMQNWADDGSGDCRAEDDRRDAVAVCGVLGIPFHFRDFSGEYWSDVFEHFLAEYAAGRTPNPDVLCNREVKFKHFLDAAQALGAERIATGHYAQVAHRGGRWRLLRGADRGKDQSYFLHQLGQTQLAATLFPIGDLEKSTLRRIAQDAGLPTHAKKDSTGICFIGERDFREFLGRYLPARTGEIRDPQGQRIAEHPGVFYFTLGQREGLNIGGVRGRAAAPWYVVGKDVANNVLYVDQDRDSPLLQSRWLQSEQAHWVTGAPPARRFSCTAQTRYRQPDESCTVDVQDDGSVQVRFERPQRAVTPGQSLVLYDGEECLGGAVIAATDAPLERQLAGSSFSSEVVA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC91_ARATH
Sequence: MKEDMEVLSLASLPVGFRFSPTDEELVRYYLRLKINGHDNDVRVIREIDICKWEPWDLPDFSVVKTTDSEWLFFCPLDRKYPSGSRMNRATVAGYWKATGKDRKIKSGKTKIIGVKRTLVFYTGRAPKGTRTCWIMHEYRATEKDLDGTKSGQNPFVVCKLFKKQDIVNGAAEPEESKSCEVEPAVSSPTVVDEVEMSEVSPVFPKTEETNPCDVAESSLVIPSECRSGYSVPEVTTTGLDDIDWLSFMEFDSPKLFSPLHSQVQSELGSSFNGLQSESSELFKNHNEDYIQTQYGTNDADEYMSKFLDSFLDIPYEPEQIPYEPQNLSSCNKINDESKRGIKIRARRAQAPGCAEQFVMQGDASRRLRLQVNLNSHKSETDSTQLQFIKKEVKDTTTETMTKGCGNFTRSKSRTSFIFKKIAAMGCSYRGLFRVGVVAVVCVMSVCSLVA
What is the function of this protein?
(Microbial infection) Compromised function in defense response pathway when interacting with the invading viral capsid protein (CP) of turnip crinkle virus (TCV) due to abnormal subcellular localization.
What are the official names of this protein?
NAC domain-containing protein 91, ANAC091, TCV-interacting protein.
What are the subcellular locations of this protein?
Nucleus. Endomembrane system; Single-pass membrane protein. Note=(Microbial infection) Nuclear localization is blocked by its interaction with the coat protein (CP) of turnip crinkle virus (TCV), thus leading to its accumulation in inclusion-like structures peripheral to the nuclei.
Protein: RS14_SALSV
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: FPG_STUS1
Sequence: MPELPEVETTRRGIEPHLVGQRVSRVLVRDRRLRWPIPEDLDVRLSGQRIEAVERRAKYLLIRAESGTLIVHLGMSGSLRLVDAASPAAKHEHVDILLESGQALRYTDPRRFGAMLWSDEPLAHVLLASLGPEPLGEDFDGDRLYRLSRGRSMAVKPFIMDNAVVVGVGNIYASEALFAAGIDPRRPAGSISRARYLKLGEEIRRILAMAIERGGTTLRDFVGGDGKPGYFQQELFVYGRGGEFCKSCGSTLREIRLGQRASVYCSRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ATPL_HALH5
Sequence: MNLLAAGIAAGLAAVGGAIAVAIIVKATLEGVTRQPELRGSLQTLMFIGVPLAEAVPIIAIVVSFILLFT
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
Protein: TIMP3_BOVIN
Sequence: MTPWLGLVVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLLKEGPFGTMVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMFSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.  May form part of a tissue-specific acute response to remodeling stimuli.
What are the official names of this protein?
Metalloproteinase inhibitor 3, Tissue inhibitor of metalloproteinases 3, TIMP-3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CCA_OCEIH
Sequence: MISEPFLKASPILTTLISNGYEGYFVGGCVRDLLLQKDIHDIDIATSATPNEVMHLFKKVIPVGIEHGTVIVRHGGESYEVTTYRQDGEYTDHRRPNDVRFVTNLAEDLRRRDFTINALAMDTSGQITDLFHGQDDLKKKLIRTVGNAEERFTEDALRILRAVRFSSQLGCTIQEDTLEAMFVIRKQIQHLAVERITIELTKLFQGQHVSKAIQYIIDLQLDEQLPIFQSGKSDIFKAMKENITPLHSFSEVIAVFHLLDPTIKIHDWIKNYKCSNHVKNDTIQLINAYHYYQSHGINNWLLYILPTKLWDGFIRLIYVIDRTTIERKQLEEITATLPIDKRSQLHLDGNDLMNWFPHRPKGKWIKILLEEVEYLVVSKQLPNEKKIIKEWVLCNQPDPN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: DUT_ANAD2
Sequence: MPVTVRVRRVGHRGPPLDLPRYESAGAAGLDLRADEPFTLAPGERRVVPTGLALELPPGHEGQVRPRSGLAARHGVGMVNAPGTIDADYRGEVGVILVNHGQAPVAFARGDRIAQLVIAPVVRAELELVDALSDSDRGAGGFGSTGQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: LPXA_YEREN
Sequence: MIDKTAVIHPSSIVEEGAVIGAGVHIGPFCFVGSQVEIGAGTELKSHVVVNGITKIGCDNQIYQFASIGEANQDLKYAGEPTRVEIGDRNRIRESVSIHRGTVQGGGLSKVGSDNLLMINAHIAHDCIIGDRCILANNATLGGHVEIDDFAIIGGMTAIHQFCVIGAHVMVGGCSGVAQDVPPFVIAQGNHATPFGINIEGLKRRGFDKESLHAIRNAYKLLYRSGRTLDEVKPEIAELADQHPAVQAFIDFFARSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_PORG3
Sequence: MSILQKLENSAAAAVKALYGTDPMEGQIQLQKTKREFKGHLTLVVFPFVKMSRKSPEATATEIGEWLLANESAVSAIEVVKGFLNLTIAPRVWLELLNEIRADINFGHKVATEDSPLVMVEYSSPNTNKPLHLGHVRNNLLGYSLSEIMKANGYRVVKTNIVNDRGIHICKSMLAWQKWGDGVTPEKAGKKGDHLIGDFYVLFDKHYKAELNSLMAEGKSKEEAEAASTLMAEAREMLRLWEAGDEKVVDLWRTMNQWVYDGFEATYKMMGVDFDKIYYESETYLVGKEEVLRGLEEGLFVKHSDGSVWADLTKDGLDEKLLLRADGTSVYMTQDIGTAKMRFNDYPINRMIYVVGNEQNYHFQVLSILLDRLGFEFGKGLVHFSYGMVELPEGKMKSREGTVVDADDLMDEMIRTAAEIAAEAGKAAEKDEEESREVARIVGLGSLKYFILKVDPRKNMTFNPKESIDFNGNTGSFVQYTYARIRSLMRRAEAAGYDIPSQLPTDLPLSEKEEALIQKVSEYAEVVSEAGRSYSPALIANYIYDLVKEYNQFYHDFSVLKEEDERIRAFRLALSEVVALTMRKGFALLGIEMPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_BURM9
Sequence: MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNAG_METPE
Sequence: MYSPDTTKYLIHLNLQAEGVVEKPDVVGAIFGQTEGLLGEDLDLRDLQRTGRVGRIDVQISSKRGETKGDILISSSLDRAETAILAASLETIDRVGPCVAHVVVEGIEDIRVTKRRKIVDRAKELLLDHFEDGSIDSYELLDEVREAIRVEKIGSLGDEKIPAGPNVMDSDAIIIVEGRADVINLLKYGIKNAVAVEGTNVPAQIVDLADKKTATAFLDGDRGGELILRELLQVADIDYVAFSPRGKSVEDMARKEIIKALRNKVPVEYVRDQFYGDVPGEKRTQDLRPQKPGASEQNSIKKENVENENESTPTSFEPISEPAPPVTLHDHMERVSGHLIARFLSPEFTILNETRADDVEMAIDQMTTEVSGLVIDRVVDQKLLDRLVGKGVEFVAARDFNGIIKRPLSIRLMKIAQ
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: ACP_ACTSZ
Sequence: MSIEERVKKIIVEQLGVKEEEVKSESSFIEDLGADSLDTVELVMALEEEFDIEIPDEEAEKITTVQSAIDYVQNNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1622_SULNB
Sequence: MGRAFEYRKAAKMKRWGTMSRVFPKLGKIITMAAKEGGLDPDMNPKLRTAILNAKAQNMPKDNIDAAIKRAAAKDAADIKEITYDVKAHYGVQMIVECATDNHTRTVANVKAILNRNGGEMLTSGSLNFMFTKKAVFVFDKTDDMDLEELELDLIDYGLEEIEEDVEPQENGNDKAIVRIYGEFTSFGELSKALEDKGIEVKKATIEYIANTPVELDEKQLEEIEALIDKLEDDEDVQNVFTNIN
What are the official names of this protein?
Probable transcriptional regulatory protein SUN_1622.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CLOBM
Sequence: MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFYNIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENFSAYNVVNSYEEEELFRIFKNYGEEKFSRKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIITFHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFDV_SHIFL
Sequence: MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYALPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCALIAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKKNSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLTLAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGIIIASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS
What are the official names of this protein?
Uncharacterized transporter YfdV.
What is the protein family that this protein belongs to?
Belongs to the auxin efflux carrier (TC 2.A.69) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YKCC_BACSU
Sequence: MSRHIQYSIVVPVYNEELVIHETYQRLKEVMDQTKENYELLFVNDGSKDRSIEILREHSLIDPRVKIIDFSRNFGHQIAITAGMDYAQGNAIVVIDADLQDPPELILEMIEKWKEGYEVVYAVRTKRKGETFFKKQTAAMFYRLLSGMTDIDIPIDTGDFRLMDRKVCDEMKRLKEKNPFVRGLVSWVGFKQTAVEYVRDERLAGETKYPLKKMLKLSMDGITTFSHKPLKLASYAGILMSGTGFLYMFIVLYLKLFTDSTITGWSSLIVIQLLFSGIVLLILGVIGEYIGRIYDEAKDRPLYIVQKSYGIENKRLYRDQHMS
What are the official names of this protein?
Uncharacterized glycosyltransferase YkcC.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GtrB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANC_SHEFN
Sequence: MITTSAISTIREHVKTWRSKGETVAFVPTMGNLHQGHITLVNEAKKRADHVVVSIFVNPMQFSANEDLDGYPRTLIQDSDKLMAAGTEILFTPTPEIIYPKGLAQQTYIEVPEIGDELCGASRPGHFRGVATIVAKLFNIVQPDIALFGRKDFQQLMIIKTMVEDLSMPIDVIGVETIREQSGLAMSSRNGYLTIEEKHSAATLKQALDSIVNAIQRGEATQQAITTAKKLLITAGFTPDYLEVRNANTLRQVTAADSELVVIGAAYLGKARLIDNVSFSRHSS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STRT1
Sequence: MLYPTPIAKLIDSFSKLPGIGAKTATRLAFYTISMSDEDVNDFAKNLLAAKRELTYCSVCGRLTDDDPCIICTDETRDRTKILVVEDSKDVSAMEKIQEYRGLYHVLQGLISPMNGVGPDDINLKSLITRLMDSEVDEVIIATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: EFP_PSEPK
Sequence: MKTGKELKPGTVLRIDNDPWLVQKAEFTKSGRNSAIMKTKLKNLLTGYKTETVYGADDKLDDVILDRKEATLSFINGDEYTFMDTTDYTMYELNAEDIEAVLPYIEEGMEDVCEAVFFEGRLVSVELPTTISRKVVYTENAARGDTSGKVMKPAKLANGTEISVADFIQIDEWIDIDTRDNSFKGRSKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLF10_MOUSE
Sequence: MLNFGASLQQASEGKMELISEKPREGMHPWDKAEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEDDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTASAPSTGHFKSFSDAAKPPGATPFKEEEKNPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHGNVEATRKNIPCAAVSPNRSKPEPSTVSDGDEKAGAALYDFAVPSSETVICRSQPAPSSPVQKSVLVSSPTVSTGGVPPLPVICQMVPLPANNSLVSTVVPSTPPSQPPAVCSPVLFMGTQVPEGTVVFVVPQPVVQSPRPPVVSPSGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPASAQ
What is the function of this protein?
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'.  May play a role in the cell cycle regulation (By similarity).  Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity.  Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver.  Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis.
What are the official names of this protein?
Krueppel-like factor 10, GDNF-inducible factor, Transcription factor GIF, mGIF, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NANA_ECO7I
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLSLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTB_BACAH
Sequence: MSMKISEKKFNDRVGDGIQDSFMRGAVSSAQTRLYTNRLKAADELGNWEEWRELGEEIRQHTLENLDYYLMQLSENVSKRGGHVYFAKTKEEAAKYIQDVAKKKQAKKVVKSKSMVTEEISMNHALEEIGCEVLESDLGEYILQVDNDPPSHIIAPALHKNRTQIRDVFKEKLGYENSDDPYEMTKFVRKQLREKFMDAEIGVTGCNFAVANTGSLCLVTNEGNADLVMSIPKTQIAVMGMERMVPTMEELDVLVGLLCRSAVGQKLTSYVTVAGPIQEEEVDGPEEFHLVVVDNGRSQILGSEFRQVLQCIRCAACVNVCPVYRHVGGHSYGSIYSGPIGAVLTPLLGGYDDYKELPYASSLCGACTEACPVKIPLHDLLLKHRQVIVEQEGRAPLAEKLAMKMFSMGASSAALYKMGSKMAPAAMSPFTSGNRVSKGVGPLKNWTDIREFPAPSKERFRDWYKDHKKGGDK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: MCSB_MOOTA
Sequence: MSLNLERNSKWMEGSGPQADIVISSRIRLARNLKGLPFPNLMNSDQQARVVSQVSRAIQAPMVFQAVGELKLQPLRELAPVERQILVEKHLISPDLAAGGGEKAVVLRDDEAVSIMVNEEDHLRLQCLLPAMMLHEAWRLADAADDALENELDFAFDQERGYLTACPTNVGTGLRASTMLHLPALVLTRQAGPVLSALTKVGVAVRGLYGEGTEAQGNIFQVSNQITLGRSEEEIINNLSAVTVRLADQEREARELLRRQSRWQLEDRVGRAYGVLTNARILSSQEALQLLSDVRLGAEMKIIRGLDQRLLNQLMVRIQPAFLQFSAGKEMTPMERDVHRAAMVRELLAG
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: NMO_STAAE
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKITEEQQFKCHIDTIIKKQVPVCCFTFGIPSEQIISRLKAANVKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVITKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELIHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: VE8E2_HPV63
Sequence: MKLTILTKRFRSSSPLRTSGSPTDTNPATQGQSTQTARKAETKGSRHHPKSPAVRKRRPYGRRRSRSPRDTTLRRGEGESARASAGSGERVAFISPGDVGTSTRSPPKGGQSRLRRLIQEARDPPIICLKGGPNQLKCLRYRIKASNSSDFESISTTWHWVHNKCTDRVGHARMLVRFISTEQRDRFLDKVVVPKSVSVILGAFDGS
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MED31_ASHGO
Sequence: MSAKSSEPPFEPSSEGEQLPSRFEVELEFVQSLANIPYVTFLLTQHQIWQDPRFKAYLKYLEYWCEPPYTQFIVYPNCLFVLKLLNSFLDKAVENEDGILEGAEDLPKVIQMQGGEWMNQMVERWRG
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGX_ECO5E
Sequence: MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGVGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.