PharMolix/UniProtQA huggingface dataset:
Protein: MTAP_BRADU
Sequence: MTQAVLGIIGGSGIYDLPGLEGAHEEVIKSPWGEPSAPLRRGTIAGLPIVFLPRHDKGHRLSPSDINYRANIDVLKRAGVTDLISLSACGSFKEEMPPGTFVLVDQFVDRTHKRESSFFGRGCVAHVSMAHPVSPRLRIHLAAAAEAEGIAIARGGTYVCMEGPQFSTYAESMTYKTSGYSVIGMTNMPEAKLAREAEICYATVAMVTDFDCWHPDHDAVTVQDIIRVLTSNADKAKALVARLAKDFPREHEPCPIGSDRALDTALITAPEARDPELLKKLDAVAGRVLRG
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: RL22_SODGM
Sequence: METIAQHRHARSSAQKVRLVADLIRGKKVSQALEVLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVAKIFVDAGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: EUTJ_SALTI
Sequence: MAHDEQLWLTPRLQKAAALCNQTPAASDTPLWLGVDLGTCDVVSMVVDGNAQPVAVCLDWADVVRDGIVWDFFGAVTLVRRHLDTLEQQLGCRFTHAATSFPPGTDPRISINVLESAGLEVSHVLDEPTAVADLLALDNAGVVDIGGGTTGIAIVKQGKVTYSADEATGGHHISLTLAGNRRIPLEEAEQYKRSNAQEIWPVVKPVYEKMAEIVARHIEGQGIADLWLAGGSCMQPGVEALFRQRFPELQVHLPQHSLFMTPLAIANSGRAKAEGLYAS
What is the function of this protein?
May protect ethanolamine ammonia-lyase (EAL, eutB-eutC) from inhibition, may function in assembling the bacterial microcompartment and/or in refolding EAL, suggesting it may have chaperone activity.
What are the official names of this protein?
Ethanolamine utilization protein EutJ.
What is the protein family that this protein belongs to?
Belongs to the EutJ family.
Protein: TRGV1_HUMAN
Sequence: MRWALAVLLAFLSPASQISSNLEGRTKSVTRLTGSSAEITCDLPGASTLYIHWYLHQEGKAPQCLLYYEPYYSRVVLESGITPGKYDTGSTRSNWNLRLQNLIKNDSGFYYCATWDR
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) gamma chain (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
Probable non-functional T cell receptor gamma variable.
What are the subcellular locations of this protein?
Cell membrane.
Protein: DGCF_ECO57
Sequence: MLADWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAFPLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISVGSPFSIPQMFSARLGIATMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTVMLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLVARMGGEEFAVAVPSVNPVDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGRASYRTLTDDFNKLMVEADTCLYRSKKDGRNRTSTMRYGEEVV
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules.
What are the official names of this protein?
Probable diguanylate cyclase DgcF, DGC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EZRA_BACHK
Sequence: MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVSTTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHGHNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQLEQEVHARHYVEQKTLSVYEDLEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSLEEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIAEYVDNEQTLS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: YHI3_SCHPO
Sequence: MSQSPIDYNESLRPDDMLDNELNYELANEVSAGDEEPYDDDIWESEDLEPVGHDIQPMDSVSDFHVKDFSEKKYSPYTDEIASAQLTGPSESAFGSASSLGTVESPVTMQSATLLWDPSVKEVDDILHNEDFYDGRDLNIFTLRGFVNILTLILLSCGLLMLFIGYPILSAVEVEKQRKKN
What are the official names of this protein?
Uncharacterized protein P22H7.03.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein.
Protein: GAL1_ACTP2
Sequence: MKPQQLATQKFSEHYGYSAAQTVFAPGRVNIIGEHTDYNDGFVMPCAINYGMAVSFSKRDDSVWRVYAIDIDEQDEFDLSRPIEPSEHKWANYVRGVVKYIQEKCPEFKQGADLAMTSDVPMSSGLSSSAALEISIGKTAQVLGDLPLGLAEIALIGQQAENKFVGANCGNMDQLTSALGQKDQVIMIDCRSLEITPTPVPHGYSIAIINSNVKHDLVTGEYNSRRQECEFAARFFGVKALRDVTPEQFIERAAELQAENELAYKRAKHIISENQRVLEAVEALKANDMVKLGQLMAGSHDSMRDDFEITIPEIDYLVELAQIAIGKNGGARMTGGGFGGCIVCLVPDGKVEHLRRIIADNYEKQTGIKETFHLCTACDGVHLI
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_WOLTR
Sequence: MKKISVLGSTGSIGKKTVDLLLKRKEEYQVEALSTCSNFALLACQAKLLNARYVAISNKRFYKDLKESLLGTGIKVEVGTEGLMNVASLPVDLSVVAVVGIAGLEPVMHVIESGTKVIALANKESIVCGGKLLLKKTEEKNVQIVPIDSEHNAIFQVLQNGNKCVEKIILTASGGSFLNYSLEQLRNVTVGQALSHPTWNMGKKISVDSATMMNKALEIIEAHNLFNISPNRIEAIVHPESIIHGIVIYKDGFNFAVLAEADMAIPISYALSWPERSALSYKLDLTKQKLTFQEPDHKRFPALKLSMEVLNSSSPHTNSIVLNAANEVAVDKFLKSRIDFLEIIKVVKLTVENFDSYTDINSLSDIINIDLESRAIAKEIIKNKVLAYS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: FA32A_MOUSE
Sequence: MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKMLEAMGTSKKSEEEKRRCLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK
What is the function of this protein?
May induce G2 arrest and apoptosis (By similarity).  May also increase cell sensitivity to apoptotic stimuli (By similarity).  In cell lines, may play a role in the inhibition of anchor-independent cell growth.
What are the official names of this protein?
Protein FAM32A, Ovarian tumor associated gene 12, OTAG-12.
What is the protein family that this protein belongs to?
Belongs to the FAM32 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_METSB
Sequence: MAKQETLVSGMAGRYAQALFALAQERGATEGVATDLATFAAMLDESEDLRNFVRSPVFSAEQQTKALDALLDRAGLSGTTTSQFLNLVASKRRLFAVADMIRDFNILHDHAVGLSRAAVTVAEPLKDEHVAALKDALAAVAGSQRVEMSVKVDPSIIGGIIVQLGSRMVDNSLKTKLNSIRARMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MIAA_PSEMY
Sequence: MAAALPPAIFLMGPTAAGKTDLALALARVLPCDLISVDSALVYRGMDIGTAKPDKAVLAEFPHALIDIRDPAESYSAAEFRADALAAMAESAARGRIPLLVGGTMLYYKALLEGLADMPSADPVVRAELEARAAVEGWEALHRELAEVDPQSAARIHPNDPQRLTRALEVYRVSGMSMSEHRLRQAAGNPEGGTSASGQLPYTVAQLAIAPAQRQILHERIAQRFQAMLEQGFVEEVEALRSRSDLHAGLPSIRAVGYRQVWEYLDGKLSREEMVERGIIATRQLAKRQFTWLRGWGDLQWLDSLACDNLPRTLKYLESVSILK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: FMT_PARDP
Sequence: MRVIFMGTPDFSVPALRAIAARHQVVAVYSQPPRAAGRGQKPRPSPVHRAAEELGLPVRTPERLKSPQDQGDFAALQADVAVVVAYGLILPQPVLEAPWLGCLNIHASLLPRWRGAAPIHRAIMAGDAETGVAIMQMEAGLDTGPVLAEARTTIGAEDTTADLHDRLAEMGAALIVETLHRLPLPAEPQPAEGVTYAQKIDKAEARIDWGRPAAQVDRQIRGLSPFPGAWCLIGGERVKLLRSRLAAGSGAPGRVLSGFTIACGEGAVEVLEAQREGKRPMPAAEILRGMALPDRLD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PSAK_GUITH
Sequence: MNAELLISLVPQTVAWSAKTSSIMILCNVLCIVSARYIIQNKNKGTALPLSGSFSTFGLPELLATTSLGHIIGSGTILGFSYIGLLS
What are the official names of this protein?
Photosystem I reaction center subunit PsaK, PSI-K, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CPFC_STRZJ
Sequence: MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYDNYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCICLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQDSFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPWIKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMPNTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVKKLIEKKGRENVKMPYLIKKMLEKAGKLPKE
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAAA_RAT
Sequence: MGTPAIRAACHGAHLALALLLLLSLSDPWLWATAPGTPPLFNVSLDAAPELRWLPMLQHYDPDFVRAAVAQVIGDRVPQWILEMIGEIVQKVESFLPQPFTSEIRGICDYLNLSLAEGVLVNLAYEASAFCTSIVAQDSQGRIYHGRNLDYPFGNALRKLTADVQFVKNGQIVFTATTFVGYVGLWTGQSPHKFTISGDERDKGWWWENMIAALSLGHSPISWLIRKTLTESEDFEAAVYTLAKTPLIADVYYIVGGTSPQEGVVITRDRGGPADIWPLDPLNGAWFRVETNYDHWEPVPKRDDRRTPAIKALNATGQAHLSLETLFQVLSVFPVYNNYTIYTTVMSAAEPDKYMTMIRNPS
What is the function of this protein?
Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-stearoylethanolamine > N-oleoylethanolamine > N-linoleoylethanolamine > N-arachidonoylethanolamine.
What are the official names of this protein?
N-acylethanolamine-hydrolyzing acid amidase, Acylsphingosine deacylase NAAA, N-acylsphingosine amidohydrolase-like, ASAH-like protein.
What is the protein family that this protein belongs to?
Belongs to the acid ceramidase family.
What are the subcellular locations of this protein?
Lysosome. Membrane; Peripheral membrane protein.
Protein: YIDD_CAUVN
Sequence: MTFYERTVDLGLRAYKLTLSPLIGRQCRFTPSCSEYTAAALKDHGPLKGSWLGLRRICRCNPFGGSGYDPPPPRHQPRKWKCEE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COAD_SHEHH
Sequence: MHKRAIYPGTFDPVTNGHADLIERAANLFEHVIIGIAANPSKQPRFTLAERVELLKTVTAHLDNVEVVGFSGLLVDFAKEQNASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHAEVANALTKKAN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCT10_ARATH
Sequence: MTEAKTGTGNERLVVEIVGAHNLMPKDGEDSSSPFVEVQFENQRLRTKVKPKDLNPIWNEKLVFHVIDVNDLRHKALEINVYNEKRSSNSRNFLGKVRVLGSSVGREGESVVQLYTLEKRSLFSSVRGEISVKHYMTTTAENGENVRRVNRSGGSKKSKKVQNVSSSMAIQQQQQQQQQQISLHNHNRGNQQQSQQNGQGQRMLPFYPHQSEIKPLVITALPSPMPGPGPRPIVYSNGSSEFSLKETKPCLGGTSNGLGGLSSHKDKTSSTYDLVEQMQYLYVNIVKAKDLSVLGEVVSEVKLGNYRGVTKKVSSNSSNPEWNQVFVFSKERIQSSVVELFVKEGNKDEYTGRVLFDLSEIPTRVPPDSPLAPQWYKIENRNGGRGNGELMVSVWFGTQADEAFAEAWHSKAGNVHIEELSSIKSKVYLSPKLWYLRISVIEAQDVAIMDKGSSLMRFPELSAKLQVGSQILRTAIASAIPTKSFSNPYWNEDLMFVVAEPFEDCVTVVVEDRLNGGAIGGQNDVAVGRVQIPISAVERRTGDTLVGSRWFSLDNGNNNNRFGSRIHLRLSLDGGYHVLDEATMYNSDVRPTAKELWKPQVGLLEIGILSATGLMPMKVRDGKCGGIADSYCVAKYGPKWVRTRTVVDSLCPKWNEQYTWEVYDPCTVVTVGVFDNARVNENNNSRDVRIGKVRIRLSTLETGRVYTHSYPLIVLHPSGVKKTGELHLAVRLSCGNAVNMLHMYALPLLPKMHYTQPLGVHMLERLRYQTLNAVAARLSRAEPPLGREVVEYMLDHDFHVWSMRRSKANFFRLVNVISGLVAVAKLVEVMRSWSKPVYSTVFVLAFLFMVLFPELLLPCLLLYTAAVGVWRFRRRSRYPPHMDARISHAETVFPDELDEEFDTFPTSRGFDVVRMRYDRVRSIAGRVQTVVGDMASQGERVQALLSWRDPRATFLFLMFCLLAAVGFYTVPVKLTVAISGLYYLRPPRFRRKLPSRGLSFFRRLPSRADSLL
What is the function of this protein?
May function as a signaling molecule by regulating the trafficking of other regulators.
What are the official names of this protein?
Multiple C2 domain and transmembrane region protein 10.
What is the protein family that this protein belongs to?
Belongs to the MCTP family.
Protein: PGAM5_DROPS
Sequence: MRKFTAFACGTGAGLLTFYLTKLNEPKAAVHNSWTRSEKPVDPCALWDHNWDLRDPKSLVKPVKNDLSQEQNRYNSELEKVVPKHARHIILIRHGEYLDVGDTDETHHLTERGREQAKYTGKRLCELGIKWDKVIASTMVRAQETADIILNEIDYEKAKVKNCAFLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFYRAYPDQTKDSYTLLVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPVNHLTNRIPRAAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: FADA_KLEP7
Sequence: MEQVVIVDAIRTPMGRSKGGAFRHVRAEDLSAHLMRSLLSRNPSLEASAIDDIYWGCVQQTLEQGFNIARNAALLAEIPHSVPANTVNRLCGSSMQALHDAARMIMTGDAGVCLIGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARLHGISREMQDQFAARSHARAWAATQSGAFKAEIIPTGGHDADGVLKSFNYDEVIRPETTVETLSTLKPAFDPVTGTVTAGTSSALSDGAAAMLLMSESRARELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSTSDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLINQMERKDAQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPI8_BOVIN
Sequence: MVDTCFLSRGLTTLAGLLLLPFGSLAASQIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVYSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPSSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAVGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPRSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETISLQPDSGVVESSYKKDQMVEELMEPLKYAEQLPVAQIIHQKPKLKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF
What is the function of this protein?
Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI.  During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity).
What are the official names of this protein?
GPI-anchor transamidase, GPI transamidase, Phosphatidylinositol-glycan biosynthesis class K protein, PIG-K.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: BLRO_ALBVE
Sequence: MFKHTLGAAALSLLFNSNAVQASPVPETSPATGHLFKRVAQISPQYPMFTVPLPIPPVKQPRLTVTNPVNGQEIWYYEVEIKPFTHQVYPDLGSADLVGYDGMSPGPTFQVPRGVETVVRFINNAEAPNSVHLHGSFSRAAFDGWAEDITEPGSFKDYYYPNRQSARTLWYHDHAMHITAENAYRGQAGLYMLTDPAEDALNLPSGYGEFDIPMILTSKQYTANGNLVTTNGELNSFWGDVIHVNGQPWPFKNVEPRKYRFRFLDAAVSRSFGLYFADTDAIDTRLPFKVIASDSGLLEHPADTSLLYISMAERYEVVFDFSDYAGKTIELRNLGGSIGGIGTDTDYDNTDKVMRFVVADDTTQPDTSVVPANLRDVPFPSPTTNTPRQFRFGRTGPTWTINGVAFADVQNRLLANVPVGTVERWELINAGNGWTHPIHIHLVDFKVISRTSGNNARTVMPYESGLKDVVWLGRRETVVVEAHYAPFPGVYMFHCHNLIHEDHDMMAAFNATVLPDYGYNATVFVDPMEELWQARPYELGEFQAQSGQFSVQAVTERIQTMAEYRPYAAADE
What is the function of this protein?
Oxidation of bilirubin and other tetrapyrroles.
What are the official names of this protein?
Bilirubin oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: DNAJ_LIMRJ
Sequence: MAEQDYYDILGVSKDASEKDIKRAYRRLAAKYHPDVNHEPGAEEKFKKINEAYETLSDSQKRAQYDQFGSAGPQGAGGQGFGGFGGGQAYSNFGGGFDDIFSQFFGGGGRTRRDPTAPRQGRDLQYAMTLDFMDAVFGKTTTIKYDRDAECKTCHGTGAKPGKSPITCPRCHGAGVITSVRQTPLGNMQTQTTCPECNGTGKIIKPEDRCDTCHGAGHVHERHELEVKVPAGVDDGQQMRLQHQGDAGENGGPAGDLYIVFRVTPSREFRRDGSTIYVDRDISFAQAALGDEVKVKTVHGDVNLKIPAGTQSETNFRLRGKGVPHLNGNGNGDEHVTVHVKTPKSLNKRQREAMLAFAAASGEDVKGVKKTVLDKLRDAFEDK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK5_TUPAK
Sequence: MTERLKVVFQEKIAPKLIEKNRYKNKHQVPVIEKIVINRGLGNASQNTKILESSLNELTLIAGQRGVLTRSKKAIAAFKLREKTPVGVAVTLRGDRMYAFLDRLINLALPRIRDFQGINPKSFDGLGNYSLGLEEQLMFPEIDYDKIDQIRGMDISIITTAKKDSEGFQILKEFGMPFKE
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARCD_CLOPE
Sequence: MAEQHNEPKKLGFAQLAALIVGSMIGGGAFNLPSDMARGAGTGAVIIGWIITGIGMIALAFVYQSLANRKPELTGGVYSYAKAGFGEYIGFNSAWGYWLSAWIGNVSYSVLLFGAVGYFLPMFGAGNNVASIIGASVLLWAFTLLILNGVSGAALINLITTIAKLVPIFLFIVISLFMFNFDKFTFQFWGTSDLGGIVTQVKSTMLVTLWCFIGIEGAVVVSGRAKKQSDVGKATVLGLIGTLIIYMLITLMALGVMDRVKLSGLENPSMAYVLEFAVGKWGAVLINLGLIISLFGSLLGWALLAAEIPYVAAKDGVLPKVFAKLNKKGTPSGSLIITNLLVQAFLILTLVASSTYQALYSVASTAILVPYLLSAMYGFKLALTGETYDKNPTGRTRDKIFGGIATVYAIWLCYAAGLKYLLLCFILYAVGIIFFYIGKKQNNKDAEVFVGKEKILAIIVLVIAIIAIVMLFNGTITI
What is the function of this protein?
Catalyzes electroneutral exchange between L-arginine and L-ornithine.
What are the official names of this protein?
Arginine/ornithine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.