PharMolix/UniProtQA huggingface dataset:
Protein: UGPE_BRUAB
Sequence: MIEQRPVSNLIGHLILILGIIIVAFPIYYTFVASSMTSTQIIRPPISLLPGDHLVENYREAIFGGVERVVGVSLERLLWNSFVVAMAIAVGKIIISFMSAFAIVFFRFPMRMFFFWMIFITLMLPVEVRILPTYKVIVDLGMIDTYAGLTLPLMASATATFLFRQFFLTIPGELVEAARIDNAGPFRFMRDILLPLSKTNIAALFVILFIYGWTQYLWPLLVTNDAKMNTIIIGLRRMVDWADASTPWNYVMVTAILAIIPLILVVVLMQRWFVKGLVETEK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpE.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y284L_PBCV1
Sequence: MCSGLRIIADDGTVVVGRTLEFGENILKFKKFVNGNIRGISTPDGKLLDGMNEHGLVIFVFYFKNYAKYGCPSQTKLNIKPTEVALFLLQKAKNVKDVKAIAKTLNVIHESYPPFTETPPMHWLVTDASGKSIVLEPLGNGELTVFDNPMGIFTNAPTFPEHMESAKKALEHLSPISDPNAASQGTGALGLPGDFSSASRFIRLAFFSQTIEIPRTSAGAVNTLFHVLNNFDIPKGVVASINMNTGKHVYEKTIYTVIYNIKSKEIVFKHYNDQNIQKL
What are the official names of this protein?
Uncharacterized protein A284L.
What is the protein family that this protein belongs to?
Belongs to the peptidase C59 family.
Protein: PHSG_SHIFL
Sequence: MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties (By similarity).
What are the official names of this protein?
Glycogen phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: FTSB_SALPK
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: XGPT_ECO8A
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TIG_OENOB
Sequence: MVDIIKTNATFKAGKGNKGTLSFEIPAKQISSGIDQAFNKQKDKINIPGFRKGHVSKELFLARFGEEALYEDALNAILPDIYDQAVNEADITVVGQPQIIPDDLKHGGPWKIHAEVTLAPTVELGDYKGVEVEKESDEVSDKELNAELERLQKGEAELVPAKEDQVSEKGDTVVIDFDGSVDGKQFDGGKAQNFSLSLGSGQFIPGFEDQLVGHKAGDDVDVKVTFPKNYQAKNLAGKEAVFAVTIHELKKLETPALDNEFAKDVDDSVSSLEELKAKTKEKLAKDKAEKNKDAFEDAAIQKVVDGAKINPEKLPEEMINDDVSRQMQTFFNNLAGQGVKPEMYFQITGTSQEQLKQQMTEGAPNRVKTNLVLEEIARVEKINPSNEEIDKEIKSLASEYNIKESEVEKSVSAGMLSHDLKVQQAVELIVNSAQAVEKK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NHAA_SULDN
Sequence: MKLYAPWQRAFEKIATPFEQFLHAQTTTGLMLMLMTVVALLLANSPLSDEYLHIFHTNIDIFVGNYGFSKSIHHWINDGLMAIFFFIIGLEIKRNILVGELSNIKVAMLPILAAIGGMALPALIYYAINYGDIGEAGWGIPMATDIAFAISALVLLGRRVSASLVTFLVALAIVDDLGAVVVIALFYTQEINMLPLLFAFISFLVLVSFNRFGIHAILPYFVVGFIMWLFMLESGIHATVAGVIAAMAIPSRPKYTPMDFTKSVKSRLDEYDNYPIEDNYMLHEQQKAILQNVKDKIDAISSPSARLEHSLHLPVSLVVIPLFALANAGVSINFSSAYDTLLQPISLGVMAGLVFGKVFGIAGISYLAIKLGIAKLPEGSTMSQVFGVAFLGGIGFTMSIFIAELAFAGNSELVFQAKIGILAASLFAGIFGFIWLRFIAKSAN
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1017_SYNE7
Sequence: MAGHSKWANIKRQKARVDAKKAQVFARLSRAMIVAARQGLPDPAANFQLRTAIEKAKAAGIPNDNIERAIAKGAGTLSGDGRQFESVRYEGYGPSGIAILIEALTDNRNRTAANLRAAFSKQGGNLGETGCVSWMFRQRGVVQLTGAIAEADLLEALLDLPAESYDLDESGAIVYCSIADLEALSTQLRQLGYPVEDSELRWIPNDYQLVTDGEQARSLLRLLDTLETLEDVCSVTANLELPPELVTALEATL
What are the official names of this protein?
Probable transcriptional regulatory protein Synpcc7942_1017.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_BACCR
Sequence: MAVKIRLKRMGAKKTPFYRVVVADSRSPRDGRFIEEIGTYNPVAQPAEVKINEEAALKWLGNGAKPSDTVRNLFSNQGIMEKFHLSKQGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RK20_CHAGL
Sequence: MTRVKRGYVARRRRKKILHLTSGFYGAHSRLFRVANQKAIRALAYSHIDRAKRKRNMRSLWICRINAVAREQNISYSYLIKSLKEKKILLNRKMLAQLAVLDKPSFIKLINTHLN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PAP1_PARPV
Sequence: GFFALIPKIISSPLFKTLLSAVGSALSSSGEQE
What is the function of this protein?
Exhibits unusual shark repellent and surfactant properties.  Forms voltage-dependent, ion-permeable channels in membranes.  At high concentration causes cell membrane lysis.  Causes death in killfish oryzias latipes in 30 minutes at a concentration of 25 micrograms/ml.
What are the official names of this protein?
Pardaxin P-1, Pardaxin Pa1.
What is the protein family that this protein belongs to?
Belongs to the pardaxin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: TAT_HV1SE
Sequence: MDPVDPNLEPWNHPGSQPKTPCNKCFCKVCCWHCQVCFLNKGLGISYGRKKRKHRRGTPQSSKGHQDPVPKQPLPTTRGNPTGPKESKKEVASKAEADQCD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: GREA_LISIN
Sequence: MATEKVFPMTLDGKAKLENELQELKTVKRKEVVERIKIARSFGDLSENSEYDSAKDEQAFVEGRITTIENMIRNAQIIDAAEAHNGLVTLGNTVTFIELPDGEEETYTIVGSAEADPFEGKISNDSPIAKGLLGHKEGEEVTIQTPAGDMSVKIEKITAS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: DIR6_ARATH
Sequence: MAFLVEKQLFKALFSFFLLVLLFSDTVLSFRKTIDQKKPCKHFSFYFHDILYDGDNVANATSAAIVSPPGLGNFKFGKFVIFDGPITMDKNYLSKPVARAQGFYFYDMKMDFNSWFSYTLVFNSTEHKGTLNIMGADLMMEPTRDLSVVGGTGDFFMARGIATFVTDLFQGAKYFRVKMDIKLYECY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.  Enantiocomplementary dirigent protein that mediates the laccase-catalyzed enantioselective oxidative phenol coupling of (E)-coniferyl alcohol to (-)-pinoresinol.
What are the official names of this protein?
Dirigent protein 6, AtDIR6.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PAB2B_XENLA
Sequence: MAAVSSVASLRGADYENGLRGGAGPSGGGQDPGEDDPMGRGTLDLDLELLTQGRRNRRVGGRTAPGRRSGGRGGSGGGAGGLEELEDEELEEEEPGELTGDQTIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSVEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFTGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVVPKRTNRPGISTTDRGFPRARYRARASSYSSRSRFYSGYTPRPRGRVYRGRARATSWYTPY
What is the function of this protein?
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product.  Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length.  Increases the affinity of poly(A) polymerase for RNA.  Binds to poly(A) and to poly(G) with high affinity.  May protect the poly(A) tail from degradation.
What are the official names of this protein?
Polyadenylate-binding protein 2-B, PABP-2-B, Poly(A)-binding protein 2-B, Nuclear poly(A)-binding protein 1-B, Poly(A)-binding protein II-B, PABII-B, Polyadenylate-binding nuclear protein 1-B, XLnPABP2-B, nPABP2-B, xPABPII-B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus.
Protein: MQO_PROMT
Sequence: MFNTGTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSSAGLESSCAKNNAGTGHAANCELNYTPIQEDGHLSTTKAFEINKSFEQSLEFWASLAEKGKLIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAKMEFTMDHGELQDWIPLIMDGRKQSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSLEGAKKNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNAKVYGKAAVGAPPMSVPHLDTRWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLFSMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSPNDWKLSTAGQRVQIIKQTSKGGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWQEKMKSSKWKNKMLELFPSIGTDINSDQEALLAIRKRNDFLLKLI
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: MOBA_MYCVP
Sequence: MTSSLPLAAVVLAGGASRRMGRDKATLPFDGPSGTTTMVERVLSVVSARCEPVFVIAAPGQALPELDAVVLRDEVRGLGPLLATGRGLRAAAEAGRSHAFVSAVDMPALTPEIIDVLAGPAERLNADVVLPWDGRDHYLAGIYRTALHTVVAALLDAGERSMRALVDAVDTQRIVLPEQPALANVNTAADLAAILPPRLGQQTAVTGASGTGNSIPN
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T229A_HUMAN
Sequence: MAGSDVDSEGPARRGGAARRPGAPGGPGSEAAAGCPEPLSTAEAPAESATLPAWMRLYFYGMHGITLDVLVSSARRFARSPDLRMLGFSSPYRCLLHSLTHFALEKVYLQQRRCPNAFVFNFLLYPSAHVGLQTLAGQALLLSLGGGAGVAVAPGALDLALQYVLALYHCQVFLKRFLRLRYGRQRRRQQQQQQQQQQQQRRGALPVPPGARVPTAAGARRRRPRGPRGAGGAPSQGLPDLPRFLFFGMHGFLDEIFFTFFFNVLGQGDGTTSGHTSLWSFFMYGSCSFVVEKLYFHLHYSRGWGTWKRVPIYVIFIYVWELSWGLGLRTCGACSWDYSHYPLNFMGLITLMYLPGWIFLSVYQDLISNVLWRVQYVPAN
What are the official names of this protein?
Transmembrane protein 229A.
What is the protein family that this protein belongs to?
Belongs to the TMEM229 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SLYX_IDILO
Sequence: MTVEKIEAQLTNLEMQLTFQEDTIDSLNKLVTEQTQQMSEMQKQIRWLGKRLKQMQENQSTDSDPADEPPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: PSBJ_NEPOL
Sequence: MSNTGTTGRVPLWFVGMIVGLAALGLLGIFFYGSYTGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NING_LAMBD
Sequence: MMAKPARRRCKNDECREWFHPAFANQWWCSPECGTKIALERRSKEREKAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIKQAQQAVNAFIRERDRDLPCISCGTLTSAQWDAGHYRTTAAAPQLRFNERNIHKQCVVCNQHKSGNLVPYRVELISRIGQEAVDEIESNHNRHRWTIEECKAIKAEYQQKLKDLRNSRSEAA
What are the official names of this protein?
Protein ninG.
What is the protein family that this protein belongs to?
Belongs to the ninG family.
Protein: RSMA_RHOBA
Sequence: MRPVSKYGQNFLIDLNLVELIARSAEIGPSDIVLEIGTGVGSLTSIMASQAGAILTVEIDQNLFQLASEELAPFPHVKMIQGDALKNKSTFRDDIMESIREAKSRLPDDSKFMLVANLPYNVATPIVSNLLHQDPPPDRIVVTIQKELGERMVAGPGSKDYGALSIWIQATCRAEIVRILPPTVFWPRPKVDSAIVRLDVDHERGNAIPDLKYFHQTVRALFFHRRKFLRSVVISAMKGRLDKPAIDEILGRLGHGETARAEELNLEQISDLVEALRQAELANE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_THEVB
Sequence: MAASLAVEKKKLKNPPLQLHYLGDRVLRQPAKRVSKVDDSIRDIARKMLQTMYSADGIGLAAPQVGINKQILVIDIHPDDPEAEPLVMINPVIKDFSEELEVCQEGCLSIPGVYLEVRRPAMVEVSYKDEWGRPQVIMAGGLLARAIQHEIDHLTGVMFVDRVENQALLRHELKEHGFTASAVRPIAA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SUFS_ECO7I
Sequence: MTYSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMESVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLEMLPNLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBAP1_RAT
Sequence: MASKKLGTDFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREMQYDFSLEKKAIEWAEDIRLIQEAQQEAERKSEEAEAKVNSKSGPEGDSKVSFSKTHSPATMPPPINPILASLQHNNILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDSNTPRGNSGSVLQDEEVLASLEQATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPTVSNIKSLSFPKLDSDDSSQKTVRLASTFHSTSCLRSGASRNFLKPSTQSSASELNGDHALGLSALNLNSGTEVPALTSSQMPSLSILSVCTEESSPPSTCPTVTPLNFSVSQVPTMPSCPQAYLELQALSPSERQCVETVVNMGYSYDCVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAEAS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).  Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.
What are the official names of this protein?
Ubiquitin-associated protein 1, UBAP-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex.
Protein: FLIM_AGRFC
Sequence: MIMAKAAAQKASAPTIDTALLAKLTGGLTDRKTIAKIGADIGHLYSEFLPDTFHSETGIAIDVEYIGSESGLMTDLIANVGQNVAVADCSLRNWCPNFMMAVGNGFVIALMERMLGASPDSIGDPDERNLSHIELDLAAMVLGRIAGVLRSGVNAPGGFEATIDPPFNANGKSAFDEMIAGLYGVTIRMKIDIGKVSSEFSLIVPQRPLLKTSIVAPKASAQALKKQEEWMDMISQQVKRSQVTLEARIKLETLTLRTISRLVAGDVIPFQDLKQDDIGVEVSANGSKLYNCEFGKSGDRYMVRVKNNVSTDDEILRHLMG
What is the function of this protein?
FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliM.
What is the protein family that this protein belongs to?
Belongs to the FliM family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Protein: SYC_MYCPA
Sequence: MTDRPRLRLHDTAAGAVRDFVPLRDGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLIALGYDVAFIRNVTDIDDKILNKAAAAGRPWWEWAATYERAFSAAYDALDVLPPSAEPRATGHITQMVELIERLIEKGHAYTGDGDVYFDVLSYPEYGQLSGHRIDDVHQGEGVASGKRDQRDFTLWKGAKPGEPSWPTPWGRGRPGWHTECVAMAHEYLGPEFDIHCGGMDLVFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLAIPAMLQRVRPAELRYYLGSAHYRSMLEFSDTALQDAVKAYVGVEEFLHRVRVRVGAVEPGEPNPRFADALNDDLAVPAALAEVHQARAEGNRALDSGDHEGALRQARSIRAMMGILGCDPLHERWETRDETSAALAAVDVLVRAELQNREKAREQRNWALADEIRNRLKQAGIEVTDTADGPQWTLGGDGK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.