PharMolix/UniProtQA huggingface dataset:
Protein: CF418_MOUSE
Sequence: MAKDLDELLDEVETKFCRLDPLRLDLGERPKGDGGGGSHSGDRNGAQEKETLRSTETFKKEDDLDSLINEIFEEPDFDRKSFQKFKSKSSSNTCVRAPMQGVSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCVACDFRIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQTDHQLRWVCGKH
What is the function of this protein?
May be involved in photoreceptor outer segment disk morphogenesis.
What are the official names of this protein?
Cilia- and flagella-associated protein 418.
What are the subcellular locations of this protein?
Cytoplasm. Photoreceptor inner segment. Note=In the retina, located at the base of the primary cilium (PubMed:22177090). Expressed throughout photoreceptors cell body including the basal body, inner segment and synaptic terminus, but not in the outer segment (at the protein level).
Protein: OPGG_SHEFN
Sequence: MVSLLSCGTSASSHIVKKALTRLSLAMAAGLCFNLAAQEPTPPIITPTSPSVTIPLQTYADEQAIVKSANNLNTETKVRFAKTANFDSDTVVKIARKLAQKPYVELKDPLPPGLAKISYDEYRDIRFKPEASIWKAEGLPYQMQLFHRGFYFQDLIEIALVEGKQASHLAYNSEFFTAGDVLSQRLPTQDIGYSGLRIHYPLNNPAYFDELMVFQGASYFRALGKGSDYGLSSRGLALNTAEPEGEEFPIFRAFWVERPNTDSNLIVVHALLDSPSVAGAYRFSVRPGENTHIDVEATLFPRVDLVKVGLAPSTSMFLHSMNGRQNTDDFRPEVHDSDALLILNGRGERLWRPLANPKQLQVSAFMDNSPQGFGLIQRERSFDAYQDLEAHYERRPSLWVEPVGNWGAGEVVLTEIPTDSEIHDNIVSYWKPKQPIAAGSEFHFTYRLIWGSEPEVDDGTVIVARTASGRAEIAKATPRRLFVIDYQVKEGNNDEIPVAKVQSSAGVVTNVVVSRQPKTNGYRLAFEMDPQDAELIELRAELKFTGPRDVETWLYRWTL
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FRSA_SALTI
Sequence: MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNVPHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWAKQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEAAQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQIDYYTLYERYFAPRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFNPVYRNFDHALQEITDWINHRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: RPOY_STAAM
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: LFTR_CAMLR
Sequence: MQKSNLYSKLLKSPDDAPVFISEKLELDFISHAYSLGLFPWTSNPVTWWCPSPRMVLFPDEIHIQKSIKKALKTYEIRLDYDFALLIKHCSLRKKTWINQEFIETYTKLFEQNLAHSVEVYENDEFIGGLYGLIIGKVFFGESMISLKKDASKIALIKLCEILKPYDFLIDCQVPNEHLKFMGAKEMIKKDFLKILEKKVSLESGFENFQNLL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_EHRRW
Sequence: MSKHTNIPMFRIGIGYDVHRFDNINNDDSNTSITICGIKINYHKKIIAHSDGDVGLHALADAILGAVGCGSIGQHFPNTDKKWKNAESSHFVIEAQKKAQERGYIISNADIIIICEQPKIMPYALEMQHYIAQFTSIDPSFINIKATTTEKLGAIGRNEGIAAQAIVLCSQQY
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LOGL6_ORYSJ
Sequence: MMDTDHTEIIKEGEAVVEAMALLQSRFRRICVFCGSSQGKKKSYQDAAVELGKELVARNIDLVYGGGSVGLMGLVSQAVYNGGRHVIGVIPKTLMPREITGETVGEVKAVADMHQRKAEMARQSDAFIALPGGYGTLEELLEVIAWAQLGIHDKPVGLLNVDGYYNSLLSFIDKAVEEEFISPSARHIIVLAPTPKELLEKLEAYSPRHDKVVPKMQWEMEKMSYCKSCEIPGLKEGNKATIQAQRGSML
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity).
What are the official names of this protein?
Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOGL6, Protein LONELY GUY-like 6.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: END4_DESVV
Sequence: MPLFGAHMSAAGGVSNAIRDIVEIGGEVLQLFTANQRQWTPKAPSAADVEAFRRRRAAFGGPVFSHASYLINIANGDGAASAKAVEALVREFERCTALGVDAVVLHPGAHLGAGRGAGILRAARNIDEVFDRCGGQTPALLLENTAGQGTCLGGGLNDLAEIIDASRHASQLGVCLDTAHAFGAGYALHTDEGYRRCMEDIEYGPGLAAVRLFHVNDSLVPCGSRKDRHTHIGEGQLGEAAFVRLLNDPVFAMHPMVLETPKEDGHAADRRNLATLRRLAGR
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RRF_SYNSC
Sequence: MSTQDLEASMRKSVEATQRNFNTIRTGRANSSLLDRISVEYYGAETPLKSLATLSTPDSQTIQIQPFDISALASIEKAIAMSELGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEEGKVALRNLRRDAIDKIKKQEKEGEFSEDQSRDEQDGVQKTLDKFIAELEKHLASKEADILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFAI_HUMAN
Sequence: MKLLHVFLLFLCFHLRFCKVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFISQYNV
What is the function of this protein?
Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways.  Inhibits these pathways by cleaving three peptide bonds in the alpha-chain of C3b and two bonds in the alpha-chain of C4b thereby inactivating these proteins (PubMed:7360115, PubMed:17320177).  Essential cofactors for these reactions include factor H and C4BP in the fluid phase and membrane cofactor protein/CD46 and CR1 on cell surfaces (PubMed:2141838, PubMed:9605165, PubMed:12055245).  The presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such cofactors leads to C3b-mediated complement activation and subsequent opsonization (PubMed:28671664).
What are the official names of this protein?
Complement factor I, C3B/C4B inactivator.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Secreted.
Protein: DEF_GLAP5
Sequence: MAVLDVLIYPDENLAKVCQPVETVDAELNTFIDNMFDTMYEHEGIGLAAPQVNVLKRVITIDIEGDKTNQIVLINPEILESSGETGIEEGCLSIPGCRALVPRKEKLTVKALNREGQTFTLEADGLLAICIQHEIDHLNGVLFVDHISQLKRQRIKEKMLKLKKQIERAK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PUR9_GEOSL
Sequence: MAKITRALISVSDKTGILDFARELAGYGVEILSTGGTAKLLRDAGLAVKDVSDFTGFPEMLDGRVKTLHPKVHGGLLGMRSNPDHVATMKAHGIEPIDLVVVNLYPFEATVAKPECTLEDAIENIDIGGPTMLRSAAKNNADVTVLVDPADYRPVLDEMKASGGAVSRETNFCLAVKVYQHTAAYDGAISNWLGARTGEGIAAYPDTVTLQFRKAQEMRYGENPHQGAAFYVERQVKEASVATARQLQGKELSYNNIADTDAALECVKQFAEGPACVIVKHANPCGVAVGGTLLEAYDRAYATDPESAFGGIIAFNRELDADTARAICDRQFVEVIIAPAVSPEATEVVAAKKNVRLLECGTWPEKQQPRLDLKRVNGGILVQDTDLDLYAELKVVTKRQPTEQEMKDLLFAWRVAKFVKSNAIVYGKGNMTIGVGAGQMSRVNSARIAAIKAEHAGLEVKGAVMASDAFFPFRDGIDNAAAVGITAVIQPGGSMRDAEVIAAADEHGMAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PUR2_BRUSU
Sequence: MKVLLIGSGGREHALAWKLAASPLLEKLYCAPGNPGIAAVAELADIGVDDHAALIAFAKEKHIDLVVVGPEAPLVTGLADEMRAEGIRVFGPSRAAAQLEGSKGFTKDLCARFNIPTGAYGRFNNAPKAKAYIRQQGAPIVVKADGLAAGKGVVVAMTLQEALDAVDSCFEGAFGAAGAEVVVEEFLDGEEASFFCICDGKTALPLGSAQDHKRVGDGDTGPNTGGMGAYAPAPVMTPEMVARTMRELIEPTMRGMAEIGAPFSGILFAGLMITSDGPKLIEYNTRFGDPECQVLMMRLNSDLLALINAAVDGRLDEVSLEWKDEPALTVVMAAEGYPANVKKGSVIRDLEKLESIDGVKLFHAGTALKDGAIVAGGGRVLNITATAATVAQAQARAYEALKLIDWPEGFYRSDIGWRAVEREKANR
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RIMO_BARHE
Sequence: MAAPRISFVSLGCPKALVDSERIITSLRSEGYEISRKHQGADLVIVNTCGFLDSARNESLANIDEALKKNGKVIVTGCLGADPDVIRQVYPNVLAITGPQAYESVIQAVHTAIPPVHDPFIDLVPPQGIRLTPRHYAYLKISEGCSNRCSFCIIPTLRGNLMSRPISDVLREAEKLVQAGVKELLVISQDTSAYGIDLKYLETPWKDRTVKTKFFDLCRELGNMGIWIRMHYVYPYPHVDDVIEFMAEKKILPYLDIPFQHASPTVLRNMKRPALVKKINRRIEKWRIICPDLTLRSTFIVGFPGETHEDFNILLEWLDEVKIERAGCFKYEAVKGAVANDLGLESIPEEVKENRWHRFMAKQQKISTHLLKKKVGKRLQVLIDESQGKIAKGRSQYDAPEIDGVVHISSRRPLRVGEFVTVKIERSDAYDLYGIAI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_XANP2
Sequence: MAAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEGLVAVESSGHYAAAIEVNAETDFVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESVTVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAVVEGQGRIGVLVALESTGDVEKLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKSFFKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEVAAAAGQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIF_HV1YF
Sequence: MENRWQVMVVWQVDRMKIRKWNSLVKHHMYVSKKAKGWYYRHHYETHHPKISSEVHIPVGQARLVTVTYWGLTTGEQSWHLGHGVSIEWRLRKYKTQVDPEMADKLIHLHYFDCFTASAIRQAVLGRPVLPRCEYPAGHKQVGTLQYLALTAWVGAKKRKPPLPSVTKLTEDRWNEHQKMQGHRGNPIMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: GSDM_RUNZN
Sequence: MECNDPFVVALKDKGYSLVAYPKTSIRPLHIYEHTIKNAFKRIWIQSEAQPTSGFIKSLFSDKIHGAIGLSDGQGIDIDLRKTNSLSSAVAAKILESYFQDSAPSFDLAFENSSSVIFHIEEIITTDADEISLRNWLNDNQNELREIYKEEIKKGNFFVATSLLRAKKMRMQFERKNKGELGVDVSKIKNLPVDAKLESKIEGSTYDRLVFETPDEGIVFGVKLVRLFFSDNGILTIDKKQDFNRVLGENMALNLFTEIQDAGFIEVT
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization via a pyroptosis-like activity (PubMed:35025633).  Makes ring-like pores with walls about 50 Angstroms thick and an interior pore diameter of 200-300 Angstroms, when integrated in liposomes (PubMed:35025633).
What are the official names of this protein?
Gasdermin bGSDM, bGSDM, Bacterial gasdermin.
What is the protein family that this protein belongs to?
Belongs to the bacterial gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin bGSDM]: Cytoplasm. SUBCELLULAR LOCATION: [Gasdermin bGSDM, N-terminus]: Cell inner membrane; Multi-pass membrane protein. Note=Upon proteolysis the protein forms membrane- associated puncta.
Protein: RL3_CALS4
Sequence: MKKGILGKKHGMTQIFDEKGEVIPVTVIEAGPCVVVQKKTVEKDGYNAIQVGFGDVSEKKLNKPLLGHFKKAGVSPKRYLREFRLDDISGYEVGTEIKVDIFKPGDRVDVTGISKGKGFAGVIKRYGARRGPMSHGSKYHRRVGSMGATTDPGRTFKGKKMPGRMGSDRVTIQNLEVVKVDPELNLLVVKGSVPGPKGSLLIIRDSVKSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CP2B9_MOUSE
Sequence: MDPSVLLLLAVLLSLFLLLVRGHAKIHGHLPPGPHPLPLLGNLLQMDRGGLLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLDPSAPRDYIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLDANGALKKCEAFLPFSTGKRICLGESIARNELFIFFTTILQNFSVASPVAPKDIDLTPKESGIGKIPPAHQIYFLAR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2B9, CYPIIB9, Cytochrome P450 clone PF26, Cytochrome P450-16-alpha, Testosterone 16-alpha hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TRHO_SHESR
Sequence: MSNVVVCALYKFVSLPHFESLREPLLSMMEQAEIKGTLLLASEGINGTVAGTQAAIDALLAWLNNQNGLENIVYKLSFDDEMPFYRTKVKLKKEIVTMGVEGIDPLKVVGTYVKPQDWNALISDPEVILVDTRNDYEVQIGTFKNAINPVTETFREFPDYVKQNLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFEEVYHLEGGILKYLEEIKQEESLWEGECFVFDNRVAVDHDLKKGQYDQCNACRMPITEAEKLSLAYVQGVSCPHCIDKISEEQRKRFVERERQVNLAKSRNEAHIGSDVNQVIEARRQKKEALRQQSVEKNKAKQANV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: FRMD8_RAT
Sequence: MEGAEGNAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLSSISAHELHRAVREVLQLPDMALEAFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTDASDDDIAMDEPSLQFRRNVFFPKRRELQVHDEEVLRLLYEEAKGNVLTARYPCDLEDCEVLGGLVCRVQLGPYQPGQPAACTVREKLDSFLPAHLCKRGHGLFAAFRGRGAKTGPCEQGLLNAYRQVKEMAGGDSERETTLGSHYRAYLLKCHELPFYGCAFFHGEVDKPTQGFLHRGGRKPVTVAISLEGVHVIDNREKHVLLGLRFQELSWDHTSPEEEEPVLWLEFDGDSEGTPVNKLLRIYSKQAELMSVLIEYCIELSQAAEPALPQESASGPQEAPSPSSAPTQRPKLRRQGSVVCSRIQHLSTIDYVEDGSGIKRVKPKRTTSFFSRQLSSSHGSYTVVQPNDNSPEQG
What is the function of this protein?
Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway.  By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (By similarity).  Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (By similarity).
What are the official names of this protein?
FERM domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane.
Protein: RL29_PHOPR
Sequence: MNAVDLRAKSVEELNAELVSLLREQFNLRMQAATGQLQQTHNLKAVRRDIARVKTVLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y1696_STAAR
Sequence: MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
What are the official names of this protein?
UPF0297 protein SAR1696.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: NHAP2_SHIBS
Sequence: MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQQHESSVSWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGTAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF1_BORHD
Sequence: MFLEKLSPIESKIKILEEKLQDINLVKNQKEYAKTVKEYNYLEKIKAKKDEYENILSQINENQKILSEEENLEMKELVKQELAHLNLKKDEVEHMIKILLLHQDENDSKNIIIEIRAGTGGEEAALFAHNLYEMYTKYSEKKKWKTELINFNETELGGFKEVSFEIKGKDVFKKLKHESGVHRVQRVPITESNGRLQTSAATVAVLPEVEDTDIEINEKDLRIDVYRSSGAGGQHVNTTDSAVRITHLPTGIVVQCQNERSQHKNKDQAMKILRARLYEFENLKKQEQRSNDRKQQVGSGDRSERIRTYNFPQNRVTDHRANISLYKLEEIMQGELDFLLDTLALKFQEQSLKDNSI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C4H2_PETHY
Sequence: MDLLLLEKTLIGLFIAIIIATIVSKLRSKRFKLPPGPIPVPVFGNWLQVGDDLNHRNLTEYAKKFGDLFLLRMGQRNLVVVSSPDLAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRGGWEYEVESVVEDVKKMKESNTNGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFVKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKEVKEKRLKLFKDYFVDERKKLANTKSMDSNALKCAIDHILEAQQKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPHIQKKLRDEIDTVLGPGVQVTEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHEAKLGGYDIPAESKILVNAWWLANNPAHWKNPEEFRPERFFEEEKHVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGQSKIDTTEKGGQFSLHILKHSTIVLKPRSF
What is the function of this protein?
Component of the floral volatile benzenoid/phenylpropanoid (FVBP) biosynthetic pathway that controls carbon flux to pigments essential for pollination or UV protection, to numerous pytoalexins synthesized by plants when challenged by pathogens, and to lignins.
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase C4H2, Cinnamate-4-hydroxylase 2, PhC4H2, Cytochrome P450 C4H2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Nucleus.