PharMolix/UniProtQA huggingface dataset:
Protein: MOC32_MAIZE
Sequence: MLRTRGPGSILDPPLGGRREAIERELKKLRAEREELDGRIRLLESQLEAGPAGFNGAAAGKGVGDDACGGSGACQSRVGNGFAPDGSLPADMIYRYSRHLLLPDFGVEGQRKLSQSSILVVGAGGLGSPLALYLAACGVGCLGIVDGDDVELNNLHRQIIHKEAYVGQSKVKSAADACREINSAIKVVEHHHTLKPCNALEIARKYDIVVDATDNLPTRYMISDCCVLLNKPLVSGAALGLEGQLTVYHHNGSPCYRCLFPTPPPVAACQRCSDSGVLGVVPGVIGCLQALEAIKVATGVGEPLCGRMLLFDALSARIRVVKLRGSSPDCTHCGENSVFTEEDFQKFDYESFTQSPMSDKAAASVNVLPESARITCREYKKLADDGEPHLLLDVRPAHHFQIASISPSHNIPLSMLEEKLPALEASLKEAGEGSALVVLCRRGNDSQRAVQLLREKGFANAKDIIGGLQAWGQDVDPDFPVY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3-2, Molybdenum cofactor synthesis protein 3-2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCRX_METTH
Sequence: MDEKKLFLTALKKKFEVEDPDEKYTNFYCFGGWEQSARKKEFTEYAKKAAEKRGGIPFYNPDIGVPLGQRKLMAYRVSGTDAYVEGDDLHFVNNAAIQQMVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMEAINHALPGGAVVQEHMVEVHPGLVEDCYAKIFTGDDNLADELDKRILIDINKEFPEEQAEQLKSYIGNRTYQVNRVPTIVVRTCDGGTVSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVIEMGTIMPARRARGPNEPGGVAFGTFADIVQASRVSDDPAKISLEVIAGAAALYDQVWLGSYMSGGVGFTQYATAAYTDDILDDFVYYGMEYVDDKYGICGTKPTMDVVRDISTEVTLYSLEQYEEYPTLLEDHFGGSQRAAVAAAAAGCSTAFATGNSNAGINGWYLSQILHKEAHSRLGFYGYDLQDQCGASNSLSIRSDEGLIHELRGPNYPNYAMNVGHQPEYAGIAQAPHAARGDAFCTNPLIKVAFADKDLSFDFTSPRKSIAAGALREFMPEGERDLIIPAGK
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit alpha, MCR II alpha, Coenzyme-B sulfoethylthiotransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase alpha subunit family.
Protein: MAO1_PSE14
Sequence: MTKTSRPLYISYAGPSLLEMPLLNKGSAFTPQERVEFNLIGLLPQNVETIEEQVTRVYSQYKQCASDLDKHIYLRSIQDNNETLFFRLLDSHLDEMLPIIYTPTVGQACQEFSKIYRTHRGLFISYPERDRIDDILRSATKDRIKIIVVTDSERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLDVGTNNRELLDDPMYMGWRHERVSGKEYEDFIALFIDAVQRRWPDVLLQFEDFAQSNAMPLLEKYRDELCCFNDDIQGTASVAVGTLLAACKAKNETLGQQKVVFVGAGSAGCGIAEHIIAAMRIEGLSESEARKRIFMVDRFGLLTEGMDNLLDFQKRLAQKTADVSGWTAGTEAFPQLLDVVTNAGATVLIGVSGQRGLFTEQVIRELHKHCAKPLVMPLSNPTSKVEATPEEILRWTDGNALVATGSPFAPVEINGRTVHIAQCNNSYIFPGIGLGVVACKASRITDRMLMAASNALAECSPMVTGQGDAVLPPLKEIQQVSRKIALAVAKEAQAEGLALETSEEALLEAIERNFWLPGYRAYRRRSV
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RL40_PYRAB
Sequence: MARFPEAEARIFKKYICLRCGATNPWGAEKCRKCGYKRLRPKAREPRGGGR
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: PG083_VACCW
Sequence: MERYTDLVISKIPELGFTNLLCHIYSLAGLCSNIDVSKFLTNCNGYVVEKYDKSTTAGKVSCIPIGMMLELVESGHLSRPNSSDELDQKKELTDELKTRYHSIYDVFELPTSIPLAYFFKPRLREKVSKAIDFSQMDLKIDDLSRKGIHTGENPKVVKMKIEPERGAWMSNRSIKNLVSQFAYGSEVDYIGQFDMRFLNSLAIHEKFDAFMNKHILSYILKDKIKSSTSRFVMFGFCYLSHWKCVIYDKKQCLVSFYDSGGNIPTEFHHYNNFYFYSFSDGFNTNHKHSVLDNTNCDIDVLFRFFECTFGAKIGCINVEVNQLLESECGMFISLFMILCTRTPPKSFKSLKKVYTFFKFLADKKMTLFKSILFNLHDLSLDITETDNAGLKEYKRMEKWTKKSINVICDKLTTKLNRIVNDDE
What is the function of this protein?
Late protein responsible for processing most or all of the viral core and membrane proteins known to undergo morphogenesis-associated proteolysis.  These proteolytic events are involved in the transformation of immature virions (IV) into mature virions (MV).  Probably cleaves at least the OPG129/A3, OPG136/A10, OPG098/L4, and OPG144/A17 precursors preferentially at Ala-Gly-|-Ala motifs.  Also seems to process Ala-Gly-|-Ser and Ala-Gly-|-Thr motifs (By similarity).
What are the official names of this protein?
Core protease OPG082, Core protease I7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C57 family.
Protein: PYRC_AROAE
Sequence: MQTISLIRPDDWHLHVRDGAALATVVPHTARRFGRALIMPNLRPPVTTAAQALEYRARILAAVPPGQHFEPLMSLYLTDNTSPDEIDRAKASGAVVAVKLYPAGATTNSDAGVTAIEKVHAVLERMEKLGMVLCVHGEVTHGDVDVFDREQVFIEQVLAPLVARFPALRVVFEHITTAEAARFVQDAGPNVAATVTAHHLLLNRNAIFAGGIRPHHYCLPVLKRETHRRALVEAATSGNAKFFLGTDSAPHSRAAKETACGCAGCYTAHAAIELYAEAFEQAGALDRLEAFASLNGPAFYGLAPNAERITLAKDAWEVPGEYEYLHDDPLVPLRAGETVAWRVL
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: IF2_BACCN
Sequence: MSKIRVYEYAKKYNISSKEIITKLKEMNIEVSNHMTMLDDEVVNKLDNEYNNEVKKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNQDKRQENFAGKQQAQTVETPDKITFSGTLTVGELANKLGKEPSEIIKKLFMLGIMATINQDLDKDTIELIASDYGIEVEEEVVIDEIEFETFIDEQDEEEGDLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIKGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGAIATLLVQNGTLRVGDPIVVGTTYGRVRAMVNDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQQALLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAESENVDIRLHRIIYKAIEEIEAAMRGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQLDTLKRFKDDVKEVAQNYECGITIEKYNDIKEGDIIEAFIMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_METCA
Sequence: MLIFDRSREGRACASLFPQTPADIRGLPGHLLRQTPPPLPEVTELDVVRHYTRLSQKNFSIDTHFYPLGSCTMKYNPKAANVLARQPGFAALHPLGTERFGQGTLSCLYELQEYLKTLTGMTAVSLSPAAGAQGEFCGVAMIRAYHDARNDHERNEILVPDAAHGTNPASAAMCGYQVREIPTNADGDVDLEALKQAVGPKTAGIMLTNPSTLGVFEHRIPEIAALVHEAGGLLYYDGANLNAILGKVRPGDMGFDVIHLNLHKTFSTPHGGGGPGAGPVGVNARLQPFLPLPMVARSGNGYRWLAESDRPQSIGRLSAFAGNVGVLLRAYVYIRLLGYPGLRRVAEYATLNANYLQKRLVEAGFDTAFPARRAAHEFILSVQRQKKEHHVTALDFAKRLLDYGFHAPTVYFPLLIPECLMIEPTETENKETLDAFVDAMAAILKEAAEEPERLGQAPHCTPVRRLDEARAARHPDLAWKPAAPVPPR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: TRX2_SHV21
Sequence: MLTDKTIIVSLTSRLFADEITKLQKKIGSILPLQDPHKLQSLDTLGLNAVCSRDVFPDYVHMFSYLSKCTLAILEEVNPDNLILTRLDPSETYQIKNVYEPMFQWDGFSNLTVIPPVFGRQQATVTLESNGFDLVFPSVVPSDLAQAIIGKLLLYNLYSRLVESDPEINIEEVNMYTTNVTHMGRHYVLDINHNNPNEALKSLDDLAVYTCILSALIPRACLRVLTILMRHDQHELLDVFRGIVPREVYEIDANALSIGDDITRMTTFITYLQSLSSIFNLGAKLHLSSYASETQTATCWISYC
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DAPE_METSB
Sequence: MSDLAHTAVELCRELLRRPSVTPLDAGAQDFLAAKLREAGFATHSVVFSDESTPDIQNLYARAGAGGRHLVFAGHTDVVPPGDSASWRFDPFGGEMEGGLIFGRGAVDMKGAIAAFAAAAMAFVAEGGAQKGSISFLITGDEEGPAINGTDKLLRWAHQRGERFDHCILGEPTNQQALGDMIKIGRRGSLNGTLTVKGVQGHVAYPHRAKNPIPHLMRLLAALTAEPLDQGTELFDASNLEIVSVDVGNPTFNVIPAEARARFNIRFNDIWTPDALAAELRARAEKAGAAAGAASALHFEPCNALAFVTQPDAFTDLVSAAIEQATGRKPKLSTSGGTSDARFIRAYCPVLEFGLVGSTMHAVDERAPVEDISALASIYADILNSYFK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MS116_PICGU
Sequence: MSWVRSVAIRTALCRQVRSRYQSYGSTRLFSSSLRSWEEPEVVTKTPKADIDHEAVKAHQESSPLKSIEVPFTSLEASRKFDKSIFRGLYNSKMKNMTVVQQRAIMPMMDTKTGVVVRAKTGTGKTLAFALPCIQAALENPQQTQKGRIQALVVAPTRDLALQIEAEFKKVLQHQTRNVHRKTDTFVLIGGRKNDLHPKAKAAIVIATPGRLEAILRDPRMLPMFSDLKYRVYDEADRLLDQGFAPTLEVIEERLRDAKAEALEPDNHFKTALFSATVDDAVTNFAHETIGKEYEYINCVDKDAEESHENIHQGIVRTQSIKDSFEASFSYILNHINDKYFKAIVFLPTITGTEYYYRVLQRAKREELYDSETATKKYGSRILRLHGKMSQSARDRTVKEFRRTSHGVLVCTDVAARGLDFNDVSHVIQMCPSSSVADYIHKIGRTARAGARGKARIFISEPEMKFIETLQRERGIVFKEDTEYVKDETSPDHFQRLGSYEQDALEEFLRTFLGFAASVSGVYRFNKQRIVEESFALYRHILNDPSAKLSVGRRFVSEVLRMPGRDAAEFFDVPGGFDMRSSNDRKSKRTFMGDGGSRSDRGFSNDRYGNSGRSYNKSRSFDRNDRSYGNDRSYSNDRKSYGNKSYGDKSYGNKAYGDKSYGDKSYGDKSYGKSYGNRSNDRSFSRGNDRGGYEKRNYGSQSRNTYGRRDDSDE
What is the function of this protein?
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns.  Also required for efficient mitochondrial translation (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase MSS116, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NEP_I72A3
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SYDND_HELPJ
Sequence: MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKSVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGARDYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQIDAEMSFCDEDDVMGVVEDLLQEIFKAIGHTISKPFKRMPYKEAMENYGSDKPDLRFELPLIEVGDCFMDSSNSIFSNIAQDPKDKRIKALNVKGADAVFSRSVLKELEEFVRQFGAKGLAYLQIKEDGIKGPLVKFLSEKGLKNILERTDAQVGDIVFFGAGDKKIVLDYMGRLRLKVAETLDLIDKDALNFLWVVHFPMFEKTENGYHAAHHPFTMPKNIECEDIEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKININEEEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSNSIRDVIAFPKTQKASCLLTDAPSPINEEQLRELHIRLRKPI
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNGF_HALH5
Sequence: MKKKNVVVFGGGTGLSVLLRGLKTFPVSITAIVTVADDGGSSGRLRKELDIPPPGDVRNVLVALSEVEPLLEQLFQHRFENGNGLSGHSLGNLLLAGMTSITGDFARGISEMSKVLNVRGKVLPASNRSIILHGEMEDGTIVTGESSIPKAGKKIKRVFLTPKDTKPLREGLEAIRKADVIVIGPGSLYTSVLPNLLVPGICEAIKQSTARKVYICNVMTQNGETDGYTASDHLQAIMDHCGVGIVDDILVHGEPISDTVKAKYAKEKAEPVIVDEHKLKALGVGTISDYFVLEQDDVLRHNASKVSEAILEGKPRTSSSIQ
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
Protein: GUN2_HYPJE
Sequence: MNKSVAPLLLAASILYGGAVAQQTVWGQCGGIGWSGPTNCAPGSACSTLNPYYAQCIPGATTITTSTRPPSGPTTTTRATSTSSSTPPTSSGVRFAGVNIAGFDFGCTTDGTCVTSKVYPPLKNFTGSNNYPDGIGQMQHFVNEDGMTIFRLPVGWQYLVNNNLGGNLDSTSISKYDQLVQGCLSLGAYCIVDIHNYARWNGGIIGQGGPTNAQFTSLWSQLASKYASQSRVWFGIMNEPHDVNINTWAATVQEVVTAIRNAGATSQFISLPGNDWQSAGAFISDGSAAALSQVTNPDGSTTNLIFDVHKYLDSDNSGTHAECTTNNIDGAFSPLATWLRQNNRQAILTETGGGNVQSCIQDMCQQIQYLNQNSDVYLGYVGWGAGSFDSTYVLTETPTSSGNSWTDTSLVSSCLARK
What is the function of this protein?
Endoglucanase (EG) that cleaves the internal beta-1,4-glucosidic bonds in cellulose (PubMed:3384334).  The degradation of cellulose involves an interplay between different cellulolytic enzymes.  Hydrolysis starts with EGs, which cut internal glycosidic linkages to reduce the polymerization degree of the substrate and creates new chain ends for exocellobiohydrolases (CBHs).  The CBH release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain.  Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units (Probable).
What are the official names of this protein?
Endoglucanase EG-II, EGII, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_SALCH
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: GLCAE_SACS2
Sequence: MDEIYLNWDKMFDEAFRIPIHEIKNDNIVFSGIGGSGIVGEIANILGVELSFKRKFTGKESLIAVSYSGTTSETINDVENAVKAGSEVIIITSGGILEKLAKEKSLKLIKIPSGFQTRYAFPYLFTPLIKMTTKRRGIKINEMELKEGVIEAKEQIKADATRLAELLINRIPVIYSSKYLAIAKRFKQEINENAKHPAFYGEIPEINHNEIESYVHGPSLVSVIVESSEIDKITEDVLNSIVIKPYFNSDEKNISSLLALAGVTSLEMAKKLNEKPDKLYNIPKARQLTSNLFKIN
What is the function of this protein?
Involved in the synthesis of UDP-N-acetylgalactosamine (UDP-GalNAc).  Catalyzes the conversion of glucosamine-6-phosphate (GlcN-6-P) to galactosamine-6-phosphate (GalN-6-P).
What are the official names of this protein?
D-glucosamine-6-phosphate 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the PGI/PMI family.
Protein: ERG6_PNEC8
Sequence: MSFELERIDIEKDREFSEIMHGKDAAKERGLLSSFRKDKEAQKIALDSYFGFWGDKCTSEKNDIHQQERFKFYATLTRHYYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGGPACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIYSIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIPKISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTIGKWLISSFIGLMEFIGLLPKGSKKVNDILLVAADSLVKAGKKEIFTPMQLWVCRKPLV
What is the function of this protein?
Catalyzes the transfer of 2 methyl groups from 2 S-adenosyl-methionine molecules to the C-24 of lanosterol, producing first eburicol (24-methylenelanosterol) from lanosterol and then pneumocysterol (24Z-ethylidenelanosterol) from eburicol.
What are the official names of this protein?
Sterol 24-C-methyltransferase, Delta(24)-sterol C-methyltransferase, S-adenosyl-L-methionine:sterol C-24 methyl transferase, SAM:SMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Protein: EFTU_JANSC
Sequence: MAKEKFERSKPHVNIGTIGHVDHGKTTLTAAITKQFGDFQDYASIDSAPEERARGITISTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQVGIPYMVVYMNKVDQVDDEELLELVEMEIRELLSSYEYPGDDIPVIPGSALAALEGRDDAIGKDSIDKLMAAVDEYIPTPARAVDQPFLMPIEDVFSISGRGTVVTGRVERGVINVGDEISIVGIRDTTKTTCTGVEMFRKLLDRGEAGDNIGALLRGVDREGVERGQVLCKPGSVDPHTKFEAEAYILTKEEGGRHTPFFANYRPQFYFRTTDVTGTVNLPAGTEMVMPGDNLKFEVELIAPIAMEDGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRPL_CORGL
Sequence: MEGVQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRTNASLADLIFTDVPGRVAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVGASRETVNKALATFAHRGWIRLEGKSVLIVDTEHLARRAR
What is the function of this protein?
Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription.  cAMP improves binding to specific DNA sequences, probably by altering protein conformation.  Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism (PubMed:16385030).  May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232).  It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source, however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate, it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281).
What are the official names of this protein?
CRP-like cAMP-activated global transcriptional regulator, cAMP receptor protein, CRP, cAMP regulatory protein.
Protein: PIL1_SALTI
Sequence: MNLSFAKGGLPAPVKNRAWQYCQMAWRGVTSKKALSRLAALSPLLLLGVGQMASATDLLAGGKDDVKATFGADSFVMMCIIIAELIVGVAMYIRTKNLLILLGLVVVIVFTTVGLTFIK
What is the function of this protein?
Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established.  Mature pilin is assembled with the help of TraQ and TraX (By similarity).
What are the official names of this protein?
Pilin.
What is the protein family that this protein belongs to?
Belongs to the TraA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Secreted. Note=Propilin is directed to the inner membrane, where it is cleaved and acetylated. Mature pilin forms filaments that are secreted to form the conjugative pilus (By similarity).
Protein: MGT4A_HUMAN
Sequence: MRLRNGTVATALAFITSFLTLSWYTTWQNGKEKLIAYQREFLALKERLRIAEHRISQRSSELNTIVQQFKRVGAETNGSKDALNKFSDNTLKLLKELTSKKSLQVPSIYYHLPHLLKNEGSLQPAVQIGNGRTGVSIVMGIPTVKREVKSYLIETLHSLIDNLYPEEKLDCVIVVFIGETDIDYVHGVVANLEKEFSKEISSGLVEVISPPESYYPDLTNLKETFGDSKERVRWRTKQNLDYCFLMMYAQEKGIYYIQLEDDIIVKQNYFNTIKNFALQLSSEEWMILEFSQLGFIGKMFQAPDLTLIVEFIFMFYKEKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFRPSLFQHVGLHSSLSGKIQKLTDKDYMKPLLLKIHVNPPAEVSTSLKVYQGHTLEKTYMGEDFFWAITPIAGDYILFKFDKPVNVESYLFHSGNQEHPGDILLNTTVEVLPFKSEGLEISKETKDKRLEDGYFRIGKFENGVAEGMVDPSLNPISAFRLSVIQNSAVWAILNEIHIKKATN
What is the function of this protein?
Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:17006639).  Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity).
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa, GlcNAc-T IVa, GnT-IVa, N-acetylglucosaminyltransferase IVa, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
[Alpha-1,3-mannosyl-glycoprotein 4-beta-N- acetylglucosaminyltransferase A]: Golgi apparatus membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Alpha-1,3-mannosyl-glycoprotein 4-beta-N- acetylglucosaminyltransferase A soluble form]: Secreted.
Protein: UP04_FRUSA
Sequence: GVPTVNAV
What are the official names of this protein?
Unknown protein 4 from 2D-PAGE.
Protein: SODM2_CAEEL
Sequence: MLQSTARTASKLVQPVAGVLAVRSKHTLPDLPFDYADLEPVISHEIMQLHHQKHHATYVNNLNQIEEKLHEAVSKGNLKEAIALQPALKFNGGGHINHSIFWTNLAKDGGEPSKELMDTIKRDFGSLDNLQKRLSDITIAVQGSGWGWLGYCKKDKILKIATCANQDPLEGMVPLFGIDVWEHAYYLQYKNVRPDYVHAIWKIANWKNISERFANARQ
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion.