PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_STRP6
Sequence: MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKYMKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYFGAVDNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLENEEKSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: LSRE_SALCH
Sequence: MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDVHLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAMFKVAGDTTFLPSTA
What are the official names of this protein?
Putative epimerase LsrE.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SUCC_XANC5
Sequence: MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASIMVNLYRLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDETEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: IF4E_APLCA
Sequence: MAERDSEPRVNIIRPDDEPEVEEERVPDPDMVIKHPLQNSWAMWFFKNDKSRDWKDNLRVITTFDTVEDFWGLYNHTLPASKLQSGCDYSVFKAGIQPMWEDAQNKKGGRWLINLNKTQRQTHLDDFWLETLLCLIGEGFDEHSEEICGATVNIRNKGDKLGLWTRDAQKTEATKKIGIKLKESLSVPPKIVIGFQAHSDTAGKAGSTVKNRFTV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
Protein: STMP1_DANRE
Sequence: MMQFILGFTLGNVVGMYLAQNYEVPNISKKIEAFKKDVEAKKKPPE
What is the function of this protein?
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly (By similarity).  Required for the formation of mitochondrial supercomplexes (SCs) (By similarity).  Also required for the activation of the NLRP3 inflammasome (By similarity).
What are the official names of this protein?
Short transmembrane mitochondrial protein 1.
What is the protein family that this protein belongs to?
Belongs to the STMP1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
Protein: RNPH_BURPS
Sequence: MTNSSLRPSGRRADQLRDVRITRHYTKHAEGAVLVEFGDTKVICTASVAERVPEFLRERGQGWLTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRALRAVFDLNALGPRTLHLDCDVIQADGGTRTASITGAFVAAHDAVTKLVAAGRIARSPITDYVAAISVGVFGGTPVLDLDYDEDSACDTDMNVVMTGAGGFVEVQGTAEGAPFSRTEMNALLDLAQAGIGELVRLQRAALEA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SSRP_RHIWR
Sequence: MARPRPAEFEKKKVVAENRRARFDYFLEQFFEAGIALTGTEVKSLRFGEGSIAESYAEVKDDQVWLVNSNVPEFSHGNRFNHEPKRPRKLLLHAREIDKMRNGVSREGMTLIPLSIYFNGRGRAKVELALAKGKKLHDKRDTEKERDWKREQQRLLRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MIND_GUITH
Sequence: MARIVVITSGKGGVGKTTVTANLGMALAQLGYRTALIDADIGLRNLDLLLGLENRVIYTALEVLSGECRLEQALIKDKRQPNLVLLPAAQNRNKDSVTEEQMKFLVNLLVNDYDYLLIDCPAGIETGFHNAIGPAQEAIVVTTPEIAAVRDADRVIGLLEANGIKQIKLLVNRLRPQMVKANDMMSVADVREILAIPLIGVIPEDECVIVSTNRGEPLVLEKNLSLPGLAFEHTACRLDGQEIEFLDLQSYSRGPLKRLRRFFLGSSTN
What is the function of this protein?
ATPase required for the correct placement of the division site.
What are the official names of this protein?
Putative septum site-determining protein MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL16_TRIL1
Sequence: MLMPKRVKHRKQMKGRMTGAACRRIEISYGEFALQATECGWVDSRQIEAARIAMTRYIKRGGKIWIRMFPDKPLTAKPAETRMGKGKGSPDSWVCVVKPGMVLYEMEGVTEEIAREAFRLAAHKLPISTKFITRGTQNEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HUTG_STAAW
Sequence: MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPSGVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEELIDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDTRAEQESTSGTSFRQILEEDDNTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLNHVSPPIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIPSDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: IF3_YERE8
Sequence: MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVKKDLTEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REN_BCTVC
Sequence: MNVIEDFRTGEPITLHQATNSVEFESVPNPLYMKLLWFERYGPIYQLKIQIRFNYNLRRALNLHKCWIELTITGSNRILTGPRFLKVLKKRLEIYLDNLGLICINNVIRGLNHVLYEEFNFVSSVIQNQSVAMNLY
What is the function of this protein?
Increases viral DNA accumulation.  Enhances infectivity and symptom expression (By similarity).
What are the official names of this protein?
Replication enhancer, REn, 16.1 kDa protein, Protein C3, Protein L3.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae replication enhancer protein family.
Protein: C70A3_ORYSJ
Sequence: MDPFLLSIILCSWIFVVVSWKKLNCMRRRLPPGPPRWPIFGNLLQLSPLPHKDFARFCTKYGPLVYLRLGTIDAITTDDPEVIREILIRQDEVFASRPRTLAAVHLAYGCGDVALAPLGPNWKRMRRVCMEHLLTTKRLESFAAHRALEAEHLCQFVWAKAQSGKPVNLREVLGAFSMNNVTRMLLGKQYFGLQSAGPGEAMEFMHITHELFWLLGLIYLGDYLPAWRWLDPYGCEKKMREVEKKVDDFHQKIIDEHRKAREAKKSASLDDDNKEDMDFVDVLLSLPGENGKEHMDDVEIKALMQDMIAAATDTSSVTNEWVMAEVIKNPRVLRKIQEELDGVVGRGRMVAESDLGQLTYLRCVVRESFRMHPAGPFLIPHESLKPTTIMGYDIPARTRIFINTHALGRNTRIWDDVDAFRPERHLPASADGGRVEISHLPDFKILPFSAGKRKCPGAPLGVILVLMALARLFHCFDWSPPDGLRPDDIDTQEVYGMTMPKAKPLVAVATPRLPPQMYGRHGKQV
What is the function of this protein?
Involved in pollen exine and anther epicuticular layer development.  Catalyzes the in-chain hydroxylation of lauric acid (C12:0) preferentially on position 7, generating 7-hydroxylated lauric acid.  Does not possess activity with other fatty acids (C14:0, C16:0, C16:1, and C18:0).  Participates in a conserved pathway of in-chain hydroxylation of lauric acid required for anther cuticle and pollen exine formation.  Directly regulated by TDR, a known regulator of tapetum programmed cell death (PCD) and pollen exine formation.
What are the official names of this protein?
Cytochrome P450 703A2, Laurate 7-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CJ062_MOUSE
Sequence: MLWAHRKKRKAATETTEDKPLESHRANDSWIKSHFSRLSEERLPTYRYVSNNGHSPESRHGEVNTTLHVDTLTTKHGERGAALHRDSFASKQKISGSSMTKEMQRESGKSPSMEDDTWAAVAACTKEIDAKGHRVANSMLQRSTTHRRKGHAESRNISPEELKALEEVEIKLKGNFLTHHETGVAGANQSHTVYSQSRHSNQSHHSYPSHQSNQSHPVYSSYQGHHPSHLSPQSYPSYSSHQSHPGHSNHQGHSGLSSHQTHLGHSNHQGHPGHSSHQSHQGQPGHPSHQSHNLPNRRNPIYGS
What are the official names of this protein?
Uncharacterized protein C10orf62 homolog.
Protein: LPXB_CAMJR
Sequence: MKTFLVCALEPSANLHLKEVLKAYKKDFGEFELHGIYDESLCKEFDLNSKPLYSSHEFSAMGFIEVLPLIFKAKKAIKELVNLTLSQTMDAVLCIDSPAFNIPFAKALKKAGSKIPRIYYILPQVWAWKKGRIPIIESHFDILASILPFDNQFFNKSTYIGHPLLDEIKEFKNQEDINHTFSKKDDEKTIAFLPGSRRSEIRRLMPIFKELSQKFKGEKILCVPSFNLEKLEVYGDISEFKIESNTPKVLKKADFAFICSGTATLEAALVGTPFVLAYKAKAIDIFIAKLFVKLKHIGLANIFCDFAGKEALNPEFLQDKVNVLNLYEAYNKYDYKAFFAKVDFLKEYLQFGSAKNLAKILNEI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: FLIW_MARSD
Sequence: MAKERKKIIRTRIGEREITNEGIIYFSRGLIGFDDKRDFALIQLSENSPFLLLQSLEDPALGLLVADPYSFMDDYEVRLSEAEKRILRVENVRQLAVLVTVTIPPGRPDETTLNLGGPIVINSEAKRGMQVPQVDSKYPTHFRPANDDPS
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDO_BACTU
Sequence: MKMSGFSIEEKVHEFESKGFLEISNEIFLQEEENHSLLTQAQLDYYNLEDDAYGECRARSYSRYIKYVDSPDYILDNSNDYFQSKEYNYDDGGKVRQFNSINDSFLCNPLIQNIVRFDTEFAFKTNIIDKSKDLIIGLHQVRYKATKERPSFSSPIWLHKDDEPVVFLHLMNLSNTAIGGDNLIANSPREINQFISLKEPLETLVFGQKVFHAVTPLGTECSTEAFRDILLVTFSYKETK
What is the function of this protein?
Catalyzes the hydroxylation of L-isoleucine to produce (4S)-4-hydroxy-L-isoleucine (PubMed:20665018, PubMed:19850012, PubMed:21821743).  Can also catalyze the hydroxylation of L-leucine, L-norvaline, L-norleucine and L-allo-isoleucine, as well as the sulfoxidation of L-methionine, L-ethionine, S-methyl-L-cysteine, S-ethyl-L-cysteine, and S-allyl-L-cysteine (PubMed:21821743).
What are the official names of this protein?
L-isoleucine-4-hydroxylase, L-isoleucine dioxygenase, IDO.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: TCPQ_YEAST
Sequence: MSLRLPQNPNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLRELDIVHPAVKVLVMATEQQKIDMGDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFTLKELDEMVVGEITDKNDKNELLKMIKPVISSKKYGSEDILSELVSEAVSHVLPVAQQAGEIPYFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKSLSEDKKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELALHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAHNVTEPGAVKTDHLYKGVDIDGESDEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGPRAPQGPRPGNWDQED
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin.  In yeast may play a role in mitotic spindle formation (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFEO_SALTI
Sequence: MFHPRARTMLLLSLPALIIGVASSLVLIASMKVASVFQQFLWQRLPASIGIAYDSPFWIVGMLTLTGIVVGLIIRYSPGHAGPDPAIEPLISMPVSPSALPGLLLALIIGLAGGVSLGPEHPIMTINIALAAAFGSRLFPRITALDWTILASAGTIGALFGTPVAAALIFSQTLSGSNDIPMWDRLFAPLMAAAAGSLTTSLFFHPHFSLPIAHYTQMRLVDIASGAIVAAIAIAAGMVAVWCLPRLHELLHRLKNPVLILGIGGFILGILGVIGGPLTLFKGLDEMQQMAFSQTLGAGDYFTLAVVKLAALVIAAASGFRGGRIFPAVFIGAALGLMLHAHVEAVPAAITVSCAILGLVLVVTRDGWLSLFMAAVVVPDTNLLPLLCIVMLPAWLLLAGKPLLAANRHEP
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRDR_ANAD2
Sequence: MRCPYCGHLEDRVVDSRETQDGQATRRRRACLSCERRFTTYERIEDVLPQVVKKDGRREAFDRAKIVEGVATACQKRPVSTEQVEALVSAVERQVQELGEREIRTAVIGEAVMQRLRTLDEVAYVRFASVYRAFRDVGEFMTELAGLARKDGEER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: KPYM_RABIT
Sequence: MSKSHSEAGSAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
What is the function of this protein?
Pyruvate kinase isoform expressed in adult tissues, which replaces isoform M2 after birth.  In contrast to isoform M2, has high pyruvate kinase activity by itself and does not require allosteric activation by D-fructose 1,6-bisphosphate (FBP) for activity.
What are the official names of this protein?
Pyruvate kinase PKM, Pyruvate kinase muscle isozyme, Threonine-protein kinase PKM2, Tyrosine-protein kinase PKM2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
What are the subcellular locations of this protein?
[Isoform M2]: Cytoplasm. Nucleus. Note=Translocates to the nucleus in response to various signals, such as EGF receptor activation or apoptotic stimuli. SUBCELLULAR LOCATION: [Isoform M1]: Cytoplasm.
Protein: GON2_CHEPR
Sequence: QHWSLCHAPG
What is the function of this protein?
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
What are the official names of this protein?
Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH-II, Luliberin II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROE_SHIFL
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFRAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: TAT_SIVAM
Sequence: MEPSGKEDHNCLPQDLGQEEIDYKQLLEEYYQPLQACENKCWCKKCCFHCMLCFHKKGLGIRYHVYRKRGPGTNKKIPGGGEEAIRRAIDLCFFNRTCSRTHTANGQTTEKKKATA
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: URE3_BORBR
Sequence: MELTPREKDKLLIFTAALLAERRRARGLKLNYPETVALITAALMEGARDGKTVAELMSEGTRILGRDEVMEGVPEMISNIQVEVTFPDGTKLITVHNPVV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECF_ECO55
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNDHIAALCAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYY_METSB
Sequence: MSEDFRPRSDFLQTLLLRGYVHQCSDLEGIDAKAQSGELVAYIGFDCTAPSLHVGSLVQIMMLRWLQKTGGKPIALMGGGTTQVGDPSGKDESRKILSLETIEANKAGIASVFSKFIAFGDGKTQALMVDNAEWLTALKYVDFLRDVGRHFSVNRMMAMDSVKLRLERDQELSFLEFNYMCLQAYDFVELNRRYGCVLQMGGSDQWGNIVTGLDLGRRLGAPQLYALTSPLLTTASGAKMGKTAQGAVWLNEDMLPVFDYWQFWRNCEDRDVGRFLKLFTELPLDETVRLESLGGAEINEAKKILATEATSMAHGREAALLAEEAARQTFEEGALAESLPSIDIDAAEIEAGLGVLAAFVKAGLVASTSEARRQIKGGGLRVNDAPVADERAALQQGDVASGVIKLSLGRKRHVLLKLV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATOA_ECOLI
Sequence: MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTAQHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL
What is the function of this protein?
Coenzyme A transferase which is involved in short-chain fatty acid degradation and catalyzes the activation of short-chain fatty acids to their respective CoA thiolesters (PubMed:1103739, PubMed:3025185).  During acetoacetate degradation, catalyzes the transfer of CoA from acetyl-CoA to acetoacetate by a mechanism involving a covalent enzyme-CoA compound as a reaction intermediate (PubMed:1103741).  Utilizes a variety of short chain acyl-CoA and carboxylic acid substrates but exhibits maximal activity with normal and 3-keto substrates (PubMed:1103739).
What are the official names of this protein?
Acetate CoA-transferase subunit beta, Acetoacetyl-CoA transferase subunit beta, AA-CoA transferase subunit beta, Acetyl-CoA:acetoacetate CoA-transferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane associated.
Protein: RL18_LEUMM
Sequence: MISKPDKNKLRVKRHKRVRGKISGTAARPRLNVFRSNANIYAQLIDDVAGVTLASASSHDAEVTGSKTEQAVKVGELIASRGKAAKIEDVIFDRGGYVYHGRVQALADSARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.