PharMolix/UniProtQA huggingface dataset:
Protein: NTE1_ASPOR
Sequence: MATDGGPLAASSASLDSSLSPLHASPSPSSTYTASSLALSAPAIAASFSVASTFSNSLIPPPPLPPPTPSTMAGWFGWVFSFFFQVIPSVLYWVITFATITLPTWLFTLFSMSLTFTMNFTTLLLIALAIVSTISWFIRYRFLNMYSRLPSEPQRKEPHLDLFPDVQEGDSKPGLANYLDEFLSAIKVFGYLERPVFHELTRTMQTRKLIAGETLMLEEEKGFCLVVDGLVQIFVKSMRDGKPNVDEGSNHMGAESSDEDDHRVDGKQGYQLLTEVKNGASMSSLFSILSLFTEDIQLRASEGSSSSASSVGPSTNARVSDSFPASPHGLEDSPRSNFVRDHGDSVAHISNSNGELLPSVPPLNLGESHAMPIQEPYPKPRSQPGKRRRKSVHPDIVARAMVDTTIAIIPASAFRRLTRVYPRATAHIVQVILTRLQRVTFATAHSYLGLNNDVLGIEKQMTKFTTQDLPNEMRGAALDRLKDKFIKERDRLGPEEIIKGIALHNPFAGRRRRSSSFLRKEAVLHAKMAAQSKRPVSMASPEDISGDRESAGPSPGDLLSTIQLSRFGPRYEHLAPKLLSPLTDKENPPFMAPVMHSSPFHRKKDAVDEDALFRESILDCIMNGIGLTSSTRDVLRKSSHTSGDISPKLLSYDSRRQKAVFTNNAFGFIDPYDSSADGETESMMSMSMTSAGGTSPIVNLREELRNDIEIVYFPQGSVLVEQGERHPGLYYVIDGFLDVGIPVSDKGEDLVGGSRPVYGQPPEEFFPTLKRTTTSSSRVSGVTSATNDTKRKRQSRKSLYLIKPGGIQGYVGSVASYRSYTDVVAKTDVYVGFLPRSSLERIAERYPIALLTLAKRLTSLLPRLLLHIDFALEWVQVSAGQVIYHQGDESDAIYLVLNGRLRSVLEGTDGKITVVGEYGQGESVGELEVMTESTRPATLHAIRDTELAKFPRSLFNSLAQEHPGITIQVSKLIAQRMRDLVELPMPEKGGEHANVGSVKTAASVVNLRTVGILPVTAGVPVVEFGHRLQNALHQIGVTNGVTSLNQAAILNHLGRHAFSKMGKLKLSQYLADLEEKYGMVLYIADTNVNSPWTQTCITQADCILLVGLAESSPSIGEYERFLLGMKTTARKELVLLHSERYCPPGLTRQWLKNRMWINGGHHHIQMGFRLTPEPSHPQAKRLGAVLKQRVQVIQAEIQKYTSRRIRQTPLYSAQTPFKGDFHRLARRLCGRSVGLVLGGGGARGIAQVGVIKALEEAGIPIDIIGGTSIGSFIGALYARDADVVPMYGRAKKFAGRMASMWRFMLDLTYPTTSYTTGHEFNRGIFKTFGDSQIEDFWLEYYCNTTNISKSRPEFHSSGYTWRYVRASMSLAGLIPPICDEGSMLLDGGYIDNLTVTHMKGLGADVIFAVDVGSIDDNTPQGYGDSLSGFWTVLNRWNPFSACPNPPTLSEIQARLAYVSSIDNLERAKNTPGCLYMRPPIDPYGTLEFGKFDEIYQVGYAYGKQYLEKLRSEGSLPLPEETEEKKKLQRTLAPRRASI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase nte1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PHS_SHELP
Sequence: MTELAQMKCEACQADAPKVTDAELAELIRMIPDWGVEVRDGIMQLERVYKFKNFKLAMEFTNKLADLAEEEFHHPGILTEWGKVTVTWWSHSIKGLHRNDFIMAAKTDQLLD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: REEP_CSIV
Sequence: MESLETKESKVFTPVYFTSRQILLPLKMISYVSRFLKFEDFRKFIRAMWPNGEANVIFQELLERLSIRKFKAKFYNREEIEVEYKFDRERSGINWILINFKDLLPILGGIMLPDDEDKFQSIFTLEDFLKRNLKVHRCSGGIHTSCHNLGRDSDSDSEAKLDICPFDHYHHFCPDHVIAWFKHYLLTAILLREGVYDELVKNANLPNADHLTSGRRRTEQYWLRVARRKKCRFSQ
What are the official names of this protein?
Repeat element protein.
Protein: AROK_CALS8
Sequence: MKNIVLTGFMGSGKTTIGRLVAEKLNIDLVDTDSEIIKEFKLTIDQIFEIHGEKKFRECEKRVIERVSKLENVVISTGGGVVLDPENVNLLRKNGVIYFLYASPENILKRLKDDNTRPLLKNGDKLSNIIRLMNIRMPFYKNCDFEINTDILSPELAAEKIISIHMAKESKR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIIA_AJEDR
Sequence: MRSPQSILAIVAFATTAIAGVVPSTEKRADDIPELDVKLTQVEGTLVKAVVTNNGDEDLNILNLNFFKDTAPVKKVSVYSQGAEVPFAGVRLRHKTSGLSPEVFTYLGPGESFEDEFDVAFTADLSQGGRIVVKAEGFASTTDTDGDTLSGVVHYKSNELEIDVDGKAAAKNFASLNQFSKRTRLTGCTGSRGSAATRAIRDSAPLAAMAAGAARNGGRAFTQYFKTNDQQVRNLVAARFDAVAREASSTTSGRTTYYCDDPYGICSPNVLAYALPSRNIISNCPAYYSLSHLTWRCHGQDRVTTSIHEFTHTPGVFSPGTDDLAYGHQAATSLSTWEALNNADSFSLFANERADVAET
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog BDCG_00922, Deuterolysin BDCG_00922.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS8_MYCGI
Sequence: MTMTDPIADFLTRLRNANSAYHDEVTLPHSKIKANIAEILKSEGYISDYRTEDARVGKSLVVQLKYGPSRERSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAIISTSSGLRTDRQASREGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PETL_TOBAC
Sequence: MLTITSYFGFLLAALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex (By similarity).  Seems not to be required for photosynthesis.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: XDHE_BACSU
Sequence: MDIKEAGPFPVKKEQFRMTVNGQAWEVAAVPTTHLSDLLRKEFQLTGTKVSCGIGRCGACSILIDGKLANACMTMAYQADGHSITTIEGLQKEELDMCQTAFLEEGGFQCGYCTPGMIIALKALFRETPQPSDKDIEEGLAGNLCRCTGYGGIMRSACRIRRELNGGRRESGF
What is the function of this protein?
Oxidizes hypoxanthine and xanthine to uric acid.
What are the official names of this protein?
Probable xanthine dehydrogenase subunit E, XDHase subunit E.
Protein: TREF_SHIB3
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_ECOLC
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNIIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY552_THETH
Sequence: QADGAKIYAQCAGCHQQNGQGIPGAFPPLAGHVAEILAKEGGREYLILVLLYGLQGQIEVKGMKYNGVMSSFAQLKDEEIAAVLNHIATAWGDAKKVKGFKPFTAEEVKKLRAKKLTPQQVLAERKKLGLK
What is the function of this protein?
This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T. thermophilus.
What are the official names of this protein?
Cytochrome c-552, Cytochrome c552.
Protein: RUVB_CHRVO
Sequence: MIETDKLFGAAPERRIVTPQRASEQEEALERALRPKLLDEYVGQKKAREQLEIFIEAAKKRGEALDHVLLFGPPGLGKTTLAHIVAREMGVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKIDLPPFTLVGATTRAGMLTNPLRDRFGIVARLEFYNAEELTRIVSRSAGLLNVQLSDDGAFEVAKRSRGTPRIANRLLRRVRDYAEVKSDGVVTMAVADAALAMLDVDPAGLDVMDRKLLQAILEKFSGGPVGLDNVAAAIGESTDTIEDVIEPFLIQQGYLQRTPRGRMATAQAYLHFGLPVKDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MRAZ_CALS4
Sequence: MLMGQYEHTIDSKGRVIIPAKFREELGEKFVLTKGLDNCLFVYSLDEWKNIEEKLKTLPLTKKDARAFTRFFLAGAVECEVDKQGRILIPSHLREHAKIEKDVIFIGVSTRVEIWSKEVWEEYSKSTDVSFEEIAEHLDNFNI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PYRR_PSEPW
Sequence: MSLPNPADLIRQMAVDLRAHLARRGITEPRYIGIRTGGVWVAQALQQELGDTSPLGTLDVSFYRDDFSQNGLHPQVRPSELPFEVEGQHLVLIDDVLMSGRTIRAALNELFDYGRPASVTLVCLLDLDAGELPIRPNVLGATLSLAAHERVKLTGPAPLALERQDLATASAL
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: EF1G_HUMAN
Sequence: MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAFQHVGKAFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma, EF-1-gamma, eEF-1B gamma.
Protein: AP1A_BRAOA
Sequence: MGRGRVQLKRIENKINRQVTFSKRRAGLMKKAHEISVLCDAEVALVVFSHKGKLFEYSTDSCMEKILERYERYSYAERQLIAPESDSNTNWSMEYNRLKAKIELLERNQRHYLGEDLQAMSPKELQNLEQQLDTALKHIRSRKNQLMYDSINELQRKEKAIQEQNSMLSKQIKERENVLRAQQEQWDEQNHGHNMPPPPPPQQHQIQHPYMLSHQPSPFLNMGGLYQEEDQMAMRRNDLDLSLEPVYNCNLGCFAA
What is the function of this protein?
Transcription factor that promotes early floral meristem identity in synergy with LEAFY.  Displays a redundant function with CAULIFLOWER in the up-regulation of LEAFY.  Required subsequently for the transition of an inflorescence meristem into a floral meristem, and for the normal development of sepals and petals in flowers.  Regulates positively B class homeotic proteins (By similarity).
What are the official names of this protein?
Floral homeotic protein APETALA 1 A, BoaAP1-a, Agamous-like MADS-box protein AP1-A.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_YERPY
Sequence: MAKTIKVTQTKSSIGRLPKHKATLIGLGLRRIGHTVEREDTPAVRGMVNLVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GLB1_TYLHE
Sequence: TDCGILQRIKVKQQWAQVYSVGESRTDFAIDVFNNFFRTNPDRSLFNRVNGDNVYSPEFKAHMVRVFAGFDILISVLDDKPVLDQALAHYAAFHKQFGTIPFKAFGQTMFQTIAEHIHGADIGAWRACYAEQIVTGITA
What are the official names of this protein?
Extracellular globin-1, Erythrocruorin, Extracellular globin I.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISCS_ANASK
Sequence: MKIPIYMDYHATTPVDPRVLEAMLPYFTTEYGNAASKSHAFGWKAEEAVEAAREEVAKLIGASAKEIVWTSGATESDNLAVKGAAHFYQAKGKHLVTCKTEHKAVLDSMHALERQGFEVTFLEPERDGRLDPAKVKAALRPDTILVSVMHANNETGVVHPIAEIGRIAREAGVVFHCDAVQSIGKIPFDVEAMNVDLASISAHKMYGPKGMGALYVRRKPRVRLVAEMDGGGHERGFRSGTLNVPGIVGMGKAAELARLERDAEAVRVTALRERLRKGLEKELDLLTVNGSLEHRVPGNLNVSFAYVEGEALMMAVKDVAVSSGSACTSASLEPSYVLRAMGVSEDLAHSSIRFGLGRFSTEEEVDYAIRLFGEKVRKLREMSPLYEMVKDGVDLNQIEWANPH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLAT_KLEOX
Sequence: MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
What is the function of this protein?
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins such as ceftazidime.
What are the official names of this protein?
Beta-lactamase TEM-12.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: XYLA_STRAL
Sequence: MNYQPTPEDRFTFGLWTVGWEGRDPFGDATRTALDPVESVRRLAELGAHGVTFHDDDLIPFGSSDSERYEHVKRFRQALDDTGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDVRDALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNGIKYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRASRLDELARPTAADGLQALLDDRSAFEEFDVDAAAARGMAFERLDQLAMDHLLGARGAAA
What is the function of this protein?
Involved in D-xylose catabolism.
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMS2_MOUSE
Sequence: MEQTEGVSTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATTIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHGSASVGTRLVFDHNGKITQKTPYPRPKGTTVSVQHLFYTLPVRYKEFQRNIKKEYAKMVQVLQAYCIISAGVRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLIPFVQLPPSDAVCEEYGLSTSRTPQNLFYVSGFISQCTHGAGRSATDRQFFFINQRPCDPAKVSKLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDANKLNVNQQPLLDVEGNLVKLHTAELEKPVPGKQDNSPSLKSTADEKRVASISRLREAFSLHPTKEIKSRGPETAELTRSFPSEKRGVLSSYPSDVISYRGLRGSQDKLVSPTDSPGDCMDREKIEKDSGLSSTSAGSEEGFSTPEVASSFSSDYNVSSPEDRPSQETINCGDLDCRPPGTGQSLKPEDHGYQCKALPLARLSPTNAKRFKTEERPSNVNISQRLPGPQSTSAAEVDVAIKMNKRIVLLEFSLSSLAKRMKQLQHLKAQNKHELSYRKFRAKICPGENQAAEDELRKEISKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALNASEMKKLITHMGEMDHPWNCPHGRPTMRHVANLDVISQN
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MLH1 to form MutL alpha.  DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex.  Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.  It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch.  DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected.  MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR.  Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages.  Possesses an ATPase activity, but in the absence of gross structural changes, ATP hydrolysis may not be necessary for proficient mismatch repair (By similarity).
What are the official names of this protein?
Mismatch repair endonuclease PMS2, DNA mismatch repair protein PMS2, PMS1 protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_XANOP
Sequence: MNDAALAPDVSAALERGLQAQSLDTAFAAPLLRYLALLVRWNKTYNLTAVRDPRAMVTRHLLDSLAMQPYIASGMLADLGTGPGLPGIPLAITRPQLQVTLVESNGKKARFMREALRHLELRNARVAESRAEALDEPTAYDHLTARALDTLAGIIAVGGHLLRPGGSLLAMKGIYPHEEIAALPEGWTMSEVHQLQVPGLDGERHLVVVRKA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCLY_RAT
Sequence: MDVARNGARGSVESPPNRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTVEHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLASVGASCHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQLEGPV
What is the function of this protein?
Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.
What are the official names of this protein?
Selenocysteine lyase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL2_MESM1
Sequence: MAIKYFKPTTNGRRNMSSLDYSKNLTGHEPTKSLMTILKKKAGRNNSGQITTRHKGSGEKRKYRLVDFKRQKDNIEAIVKTIEYDPNRSANISLIVYKDGFKSYILYPKGLKVNDVIVSGEDVDIKIGNTLPLKNIPEGTFIHNIEMQPKGGAIIARSAGSSAQILGKDDNGKYVVLRLKSGETRRILAECRATIGVVGNEEHSLVNVGKAGRNRHKGIRPTVRGSAMNPNDHPHGGGEGKQPIGRKSPMTPWGRKALGPKTRKTNKSSTKLIIRGRKKRINN
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: YFZ2_SCHPO
Sequence: MKLSSLPSGLGLASLLGLISSATAYSATDLTTMYDWNQIIKPLEWGQLNFIHTTDTHGWLGGHLRDARYKADFGEFKSFALRMKELADFKGVDLLMVDTGDLHDGNGLSDASDPQGIYTNNIFTYLPYDILTIGNHELYQAAISNNTHEYFVPHWNGTYLASNVQIYNSSNELEQFGGESTYFITKHGVRTLAMGFLFNFSSNANNTVVTPVETAIKSEWYQQQINRTDVDLFLLIGHIPVRDYDEWKSLHASIRKVHPNTPIQILGGHSHIRDFAVYDEASVSLEGGRYCETVGWLSIDGLSASNATRQYVGRPVTNETRQSYPNLPKPATPLYYTRRYIDFNRQNFRFHTQQSEDSFDTPEGVELSKVIKQYRDDLNLSYVFGCIPKNYYMTEVSPQAEDSIFKLMVDHILPEVLVNENRSSVPHIIISNGGGVRGSMYEGTFGPDEMFQLNPFLTNYYNYIPDVPYKYAKKLYSILNGGSTLRNVNDYLAALNPGYVTSDDFGEDGDDTVHTYVSTYAVPNVLQAQVGFNTTSAPETVDVVFLNYFQTKVLKALNTMVNETIYTLSNVTQYWVREDGKDSSPYMFAQYVQQEWSDYCD
What are the official names of this protein?
Uncharacterized protein C1039.02.
What are the subcellular locations of this protein?
Membrane.
Protein: HXUB_HAEI8
Sequence: MKMRPRYSVIASAVSLGFVLSKSVMALGQPDTGSLNRELEQRRIQPEAKPSGELFNQAAKSPYTAQYKQELKFPLTQVQILDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRNNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNTSEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKYTGRYRLAAGTKVNNLTGWGDELKLDLLSSNQANLKNARIDYSSLIDGYSTRFGVTANYLHYKLGGNFKSLQSQGHSHNLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDEQQAVTVKQKRKINSLTVGIDGSWNLIKDGTTYFSLSTLFGNLANQTNEKKHNAKEDFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKHYLPVFSQSVLVSSLFYDYGFGKYYKNSQSLAQSVKNSVKLQSVGAGLSFSDAGSYAINVSVAKPLDNNIDNADKHQFWLSMIKTF
What is the function of this protein?
Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of HuxA.
What are the official names of this protein?
Heme/hemopexin transporter protein HuxB.
What is the protein family that this protein belongs to?
Belongs to the TPS (TC 1.B.20) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SYDND_LEGPA
Sequence: MRTHYCSAVNELSLDKQITVCGWVHNRRDHGGVIFLDIRDRSGLLQVVYEPENKEIFAIAEKLRSEFVVRVTGIVRKRPEGMINDKMETGRVEVIGIQLEILNQSPTPPFLPDDHQIINEDLRYKYRYIDLRRAVMQKKLTLRHKLNSCIRNYLNEQNFLDIETPMLTKATPEGARDYLVPSRVHPGQFYALPQSPQLFKQLLMMSGFDKYYQIVRCFRDEDLRADRQPEFTQLDIEMAFINEEDILQLIEGLLKVVFKEILNITLPDKLPRMSYKEAMTRYGSDKPDLRNPLELIDIADLVKDCDFNVFASAANDNSGRVVALKLPNGCDLSRKDLDNYGQFVTIYGAKGLAYIKVNDLSAGMAGLQSPILKFLSETAVQSILNRVEAQTGDVIFFGADKAHVVNESMGALRNKLGHDRNLINPGWQLLWVIDWPMFELDPQSNKLQPMHHPFTSPQELSAEALRSKPTQTLAKAYDIVINGYEIGGGSIRIHQPELQKTVFDLIGIDEQEAHEKFGFLLDALQYGAPPHGGIALGIDRLAMLLTDSTSIRDVIAFPKTQTASCPLTSAPSPAGNAQLTELGIRLAPTITTK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.