PharMolix/UniProtQA huggingface dataset:
Protein: SPZ4_DROME
Sequence: MVRTQMDRRSPITRLITIEVIGYLLILMTIALPLSSAGFGFDSANSCSPNGKISRRGRAQILAAIPCDLGQQAFCHLPGSAYPWHAVRRFVHENQGLMKRMYGDVRHISILRDEIQNNEVDADDIEETAERYSKDGGRRSAKYLMNNRDRDREREDFGSFKSNDVLMEPHFRPVSTITTSTTKATTTTTTAPEIVSSTTERVPNEVTDTTPGNTNSTISTTKGTAPPLHEKPESETDIVEIQPSPESNSVYEVVSPSVLSTTSTAKPSSAAGENIQIIDSPQLGLRNLSAEASPSQEPPTATTGKPTSVPKSTTPLPIRKRKPAETTTSAASPKVSSTISTPTTTTATLLIRRNVTKYSPASVTTPVSFASLFSGTSSGLFSPERLRRPLTTTSSTSAPASSPPAGGTPASSSTGSASKSGLLREGQLFQDAMKQEPVAVASNLRGVNACPVKDEVVAPFWANNTRGEVLALLNLYPFEQYVHWEKCTHEFKQMFCRDGCRCEQQYRLHRLLAYDPHNECRGIFSDWFRFPSSCICKCYNIPMEFRATSRSPRSDSRFDAPKSDPIEAAEAEVQRAIYEHATEEWYRPRDEFDFLED
What are the official names of this protein?
Protein spaetzle 4, Protein spatzle 4.
Protein: GLR3_CAEEL
Sequence: MFWIAKTLIAFLILLKTDCYKIAIPANLIDEVNPVLEFVDFRVQVIPYETKPLWRIKQESFKIVGISIENGLFSVCNCLILGASAIILPEQYDGHLAAAAIVQSIADNTNVPCVSLHLSPPTRPSTHLHPHLNAKSLAVAAFIKREKWKDVVVVFEEPDELLEITDMITAGHFDPDSFSSQLVRLKHGDDYGNELKHIKNKLDRYRIVINIPLQKALHFLEQAANMSMCGVLYHYVVMDMDLVTVDIDSIRGIEDCNITSFGVHDVNSEYIEDIRQEIVHKSSIRLPKKGVPYTTSIWIDTLRLLIRSMKSIQIWDEPRCGSSWKSGSDIKKRFFENPLAGISGDLHWAPSGERSNYTLHVYRRTLSFQKFAEWSSRTRRIASSEAVVIANSSEKLTLEGKHLKISVYLEAPFVMITSNGSYEGYCIDLLHKIANILKFTYTIQKVRDNAYGSKESNGKWSGMVGELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDSDWFKFMDPLSTQVWIMTFASYFVVSVAIWIIAKISPYEQFERDEDNGQYKPVDNQFSLRNSFWFTVCSLMQQGSELCPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAAQTKIKYGTLGRGSTMSFFNESKIETYERMWQLMSSSPGLFVQSSKEGIARVKSSDYAYLMESSMLEYAVERDCELMQIGGLIDQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVVCEQPKRKDQDDGESIGGIFIILVVGLVLTAVLVIFELITTRKPSPAQSQVIRHVNVIPSFKLGFFRWNVN
What is the function of this protein?
Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor in the ASER neuron where it triggers a calcium response to activate cold avoidance behavior in response to temperatures below 19 degrees Celsius (PubMed:31474366).  Possibly functions as a metabotropic cold receptor and acts upstream of the G(o) G protein goa-1 in the ASER neuron (PubMed:31474366).  Also functions in cold sensing in the intestine (PubMed:31474366).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate glr-3.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: XPO1_HUMAN
Sequence: MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD
What is the function of this protein?
(Microbial infection) Mediates the export of unspliced or incompletely spliced RNAs out of the nucleus from different viruses including HIV-1, HTLV-1 and influenza A.  Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins.  Involved in HTLV-1 Rex multimerization.
What are the official names of this protein?
Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Note=Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.
Protein: RL28_ESCF3
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CSK_HUMAN
Sequence: MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHELHL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response.  Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1.  Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation.  To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane.  Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
What are the official names of this protein?
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Mainly cytoplasmic, also present in lipid rafts.
Protein: RS17E_HALLT
Sequence: MAIKPKYIKQLGNVLLERYPDSFNTDFETNKDSVTTLTTVESKGVRNRIAGYVTQKKAQAAQKA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: P33MX_CHICK
Sequence: MSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGETTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF
What is the function of this protein?
Potential NADPH-dependent oxidoreductase.  May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity).
What are the official names of this protein?
Putative monooxygenase p33MONOX.
What is the protein family that this protein belongs to?
Belongs to the P33MONOX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRD_SHIF8
Sequence: MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDVLGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APAH_HAEIE
Sequence: MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKVKPRDRVDAIFNAPDFDEQIHWLRHQPLLVHSEELNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQPDRWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGIYALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: FOL1_DICDI
Sequence: MDKIIIKDLLIQAVIGVNPGERIIKQNIIISVTAYKDLSKCGSSDNVIDTVSYSSLSKSICSYSESSHHYTLEALATGVAKICCLGFGIERVKVLVQKPGAIKLAKWPGVQIERTLDYFKSNSFVEIPSKLINNNKNSNNSNAGNNIVYLAFGSNLGDKFQNILNSFKRLEKQCFIQSTSFMYESSPQYYREQDSFYNCACKVSTDLKPHDLLKFIKQIENDMGRVETFRNGPRVIDIDIIYYNGLIIKTDDLEIPHPLMWERDFVLLPLSDIAPNFIHPTLHITTNRMKLNLPNGGNIHNIPPPPTATTTCNNIIEKVIRIGNLNYNWNDKTFIMGILNVTPDSFVDGGKFNTLEKSIQQATALIEQGADIIDIGGQSTYPGAQQISIEEEINRVVPTIKKIREVLGNDIPLSIDTLHHQVAKEAILAGCNIINDVSGEFRVPIILNHSQPTTQYLQQKQNEQYLNNSNDSNSNSSINTNGEDNNNNNNNNNNNNNNNNNNNNNNNNNDDNDNDNRSKIKQKIDLSSPKIETCTKLGLFRWQIILDPGLGFYKTYEQSIEILQRGKELMGLGFPVLIGPSRKGFIANTIANAEKDKSLPPPSPKSERRLWGTIACCCIGSMWGANIIRIHDIPEIRDAMLISDSVNKPQRRYQIQK
What is the function of this protein?
Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
What are the official names of this protein?
Folic acid synthesis protein FOL1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DHPS family.
Protein: AROA_BURA4
Sequence: MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYEQNEGFPPLRIKPGTISVDAPIRVRGDVSSQFLTALLMTLPLVKAKDGRTVVEIDGELISKPYIDITIRLMERFGVTVERDGWQRFVAPAGVRYRSPGRIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVSMGDDWIEVRGIGHDHGKLDPIDMDFNLIPDAAMTIAVAALFASGTSTLRNIASWRVKETDRIAAMATELRKVGAIVEEGADYLVVTPPQRLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_KOSOT
Sequence: MAVPKQKRSRSRTHHKRVKIYRPIKVAVSVCPNCGEPKEPHRVCLHCGYYGGKQILEIGE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DNBI_EBVB9
Sequence: MQGAQTSEDNLGSQSQPGPCGYIYFYPLATYPLREVATLGTGYAGHRCLTVPLLCGITVEPGFSINVKALHRRPDPNCGLLRATSYHRDIYVFHNAHMVPPIFEGPGLEALCGETREVFGYDAYSALPRESSKPGDFFPEGLDPSAYLGAVAITEAFKERLYSGNLVAIPSLKQEVAVGQSASVRVPLYDKEVFPEGVPQLRQFYNSDLSRCMHEALYTGLAQALRVRRVGKLVELLEKQSLQDQAKVAKVAPLKEFPASTISHPDSGALMIVDSAACELAVSYAPAMLEASHETPASLNYDSWPLFADCEGPEARVAALHRYNASLAPHVSTQIFATNSVLYVSGVSKSTGQGKESLFNSFYMTHGLGTLQEGTWDPCRRPCFSGWGGPDVTGTNGPGNYAVEHLVYAASFSPNLLARYAYYLQFCQGQKSSLTPVPETGSYVAGAAASPMCSLCEGRAPAVCLNTLFFRLRDRFPPVMSTQRRDPYVISGASGSYNETDFLGNFLNFIDKEDDGQRPDDEPRYTYWQLNQNLLERLSRLGIDAEGKLEKEPHGPRDFVKMFKDVDAAVDAEVVQFMNSMAKNNITYKDLVKSCYHVMQYSCNPFAQPACPIFTQLFYRSLLTILQDISLPICMCYENDNPGLGQSPPEWLKGHYQTLCTNFRSLAIDKGVLTAKEAKVVHGEPTCDLPDLDAALQGRVYGRRLPVRMSKVLMLCPRNIKIKNRVVFTGENAALQNSFIKSTTRRENYIINGPYMKFLNTYHKTLFPDTKLSSLYLWHNFSRRRSVPVPSGASAEEYSDLALFVDGGSRAHEESNVIDVVPGNLVTYAKQRLNNAILKACGQTQFYISLIQGLVPRTQSVPARDYPHVLGTRAVESAAAYAEATSSLTATTVVCAATDCLSQVCKARPVVTLPVTINKYTGVNGNNQIFQAGNLGYFMGRGVDRNLLQAPGAGLRKQAGGSSMRKKFVFATPTLGLTVKRRTQAATTYEIENIRAGLEAIISQKQEEDCVFDVVCNLVDAMGEACASLTRDDAEYLLGRFSVLADSVLETLATIASSGIEWTAEAARDFLEGVWGGPGAAQDNFISVAEPVSTASQASAGLLLGGGGQGSGGRRKRRLATVLPGLEV
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework-associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: SYP_ACIB3
Sequence: MRASRFLFATLRETPNDAEVISHQLMLRAGMIRKLASGLYTWLPMGTRVLKKVDAIVREEMNRSGAMEVFMPVTQPASLWEESGRYEQYGPELLRFKDRHDNPFVLGPTHEEVITDLARNELKSYKQLPVNFYQIQTKFRDEIRPRFGVMRSREFIMKDAYSFHATQESLQETYDVMYDTYSRIFTRLGLDFRPVQADTGSIGGSASHEFHVLAASGEDDIAFSTESDYAANVEMAEAVLVGERAAPTQEFKLVETPNQKTIADVCQFLNADPKQSVKALLVQGVADEKGNVPVVALFLRGDHELNEIKAEKHPLVAAPLAFATEEQLQAFGLTAGFTGPQGLVEKGITVIVDRAASVLSDFVAGANEADKHAIGVNWERDAQITEVFDLRNVVEGDPSPDGKGTLQIKRGIEVGHIFQLGTKYSEALGCKVLGEDGKPFTVTMGCYGIGVTRVVAAAIEQNYDDKGIIWPQAIAPFEIAIVPMNAHKSPRTLEAAEALYAELQAQGFDVLLDDRNERPGVKFSDLELMGIPHRIVIGEKGLDAGTFEYKGRRDAEASNLTKEELLAKLAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPL1_MOUSE
Sequence: MASVGLQFQASAGDADPQSRPLLLLGQLQHLHRVPWSHVRGKLQPRVTEELWQAALATLNPNPTDSCPLYLNCATVAALPSRVSRHNSPSAAHFITRLVRTCLPPGTHRCILMVCEQTEVFASACALARAFPLFTHRSGASRRAEKRTVMVEFFLVGQDNGPVEVSTLQCLTNATEGVRLAARIVDTPCNEMNTDIFLEEIIQVGKELGITPTIIRDEQLKTKGFGGIYGVGKAALHPPALAILSHTPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQGFKDNLHAVFCLAENAVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDLGADIIVDMATLTGAQGIATGKYHAAVLTNSAEWEAACVKAGRKCGDLVHPLVYCPELHFSEFTSAVADMKNSVADRDNSPSSCAGLFIASHIGFDWPGVWVHLDIAAPVHAGERATGFGVALLLALFGRASEDPLLNLVSPLDCEVDAQEGDNMGRDSKRRRLV
What is the function of this protein?
Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable aminopeptidase NPEPL1, Aminopeptidase-like 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
Protein: ASIC5_HUMAN
Sequence: MEQTEKSKVYAENGLLEKIKLCLSKKPLPSPTERKKFDHDFAISTSFHGIHNIVQNRSKIRRVLWLVVVLGSVSLVTWQIYIRLLNYFTWPTTTSIEVQYVEKMEFPAVTFCNLNRFQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTGSREATDFAASHQNFSIVEFIRNKGFYLNNSTLLDCEFFGKPCSPKDFAHVFTEYGNCFTFNHGETLQAKRKVSVSGRGLSLLFNVNQEAFTDNPALGFVDAGIIFVIHSPKKVPQFDGLGLLSPVGMHARVTIRQVKTVHQEYPWGECNPNIKLQNFSSYSTSGCLKECKAQHIKKQCGCVPFLLPGYGIECDLQKYFSCVSPVLDHIEFKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPSQKALKYLSKKLNQSRKYIRENLVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYLFTNFYWICIFFLLKISEMTQWTPPPQNHLGNKNRIEEC
What is the function of this protein?
Cation channel that gives rise to very low constitutive currents in the absence of activation.  The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.
What are the official names of this protein?
Acid-sensing ion channel 5, ASIC5, Amiloride-sensitive cation channel 5, Human intestine Na(+) channel, HINaC.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CENL1_HUMAN
Sequence: MGRVRNRATAQRRRRKRPGDPPAACAAIAVTGASRAQCPRVQVGVGSHAAAKRWLGRWRRKRRWRRVRKAGPRDLLPSAPTPDPPGPAPSPKDLDLGAQRERWETFRKLRGLSCEGAAKVLLDTFEYPGLVHHTGGCHCGAVRFAVWAPADLRVVDCSCRLCRKKQHRHFLVPASRFTLLQGAESIVTYRSNTHPALHSFCSRCGVQSFHAAVSDPRVYGVAPHCLDEGTVRSVVIEEVGGGDPGEEAAEEHKAIHKTSSQSAPACPREQEQ
What are the official names of this protein?
Centromere protein V-like protein 1, Centromere protein V pseudogene 1.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: THII_LACCB
Sequence: MQYSEIMVRYGELSTKGKNRQAFIGRLNGNVTRALHEFPRLTIRPKRDRMHIELNGEPSDQVMARLSQVFGIQNFSPSIAVEKDMDKVHAVALQLMNETAPKGISYKVNTRRSDHDFALDTNAMNLDLGDYLTDKRPDLVVKMHQPDMILRVEVRREAIYLSTKTIQGAGGLPVGTAGKAALMLSGGIDSPVAGYYALKRGVDIEMVHFFSPPYTSQQALNKAKQLTAKLTPYVGRIYFIEVPFTEIQEEIKAKVPEGYLMTVQRRLMLRLTEAIAQQRGDLAIFNGESVGQVASQTLESMAAINDVTTMPIIRPVATMDKNEIIAEAEKIDTYDLSIMPFEDCCTIFAPPSPKTRPKTDRARYYESKIDVAGLMDRALAGVKIQEIKSSDQFMNQDQDVIAELL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_VIBVY
Sequence: MNDVIRDFFKMESAGGILLVIAAAIAMVIANSPLNESYQAVLHTYVFGMSVSHWINDGLMAIFFLLIGLEVKRELLEGALKSRETAIFPAIAAVGGMLAPALIYVAFNGNDPEAIKGWAIPAATDIAFALGIMALLGKRVPVSLKVFLLALAIIDDLGVVVIIALFYSGDLSTLALTVGFAMTGVLFMLNAKNVTKLIWYIVVGFILWVAVLKSGVHATLAGVVIGFSIPLQGKKGEHSPLKHMEHALHPYVAFAILPVFAFANAGISLEGVSLSGLTSMLPLGIALGLLVGKPLGIFTFSWAAVKFGVAKLPEGVNFKHIFAVSVLCGIGFTMSIFISSLAFGGANPDFDTYSRLGILMGSTTAAVLGYFLLHVSLPKTAAESEKAIS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLPA_PYRAR
Sequence: MSIEVVDVRPHERHYGVYVVRFEDGTERIATKNLTPGKRVYGERLIKWGGDEYREWNPYRSKLAAAIVNGLKLVPIREGTHMLYLGAASGTTPSHISDIVGEKGLIYSVEFSPRVFREFMEKLVDQGRRNVVPILGDARFPYQYAHYIKGVDVVYIDVAQPAQAKILADNADYFLKPGGYVMLVIKAMSIDVTAPATETFKQEINTLKERGYEILETVHLEPYDTAHAMVIARKK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: TRPE_VIBCH
Sequence: MNKAINIKKTAPLEVLHSELPYTQDPTALFHALCAGRSDCLLLESAEIDSKQNLKSLLLVDAAVRIVCEGHQVTYHALSANGQALLNIIHSNLTDRIPCKVEKAKLTLTFSTPCDTLDEDSRLREASSFDALRLVQHSFDLTDHGKFALFLGGLFAYDLVANFEPLGEAPADNQCPDYVFYVAETLMVIDHQRETCQLQATQFQPGDALHSQLKSRMREIRAQVNQKLPLPSAQSLSDVEVTTNISDAAFCDIVRDLKQYVVKGDVFQVVPSRRFRLPCPSPLAAYQRLKQSNPSPYMFYMQDERFTLFGASPESALKYEMHTNQVEIYPIAGTRRRGKRADGSIDFDLDSRIELELRTDKKENAEHMMLVDLARNDVARISQAGTRHVADLLQVDRYSHVMHLVSRVVGQLREDLDALHAYQACMNMGTLTGAPKIRAMQLIRDVEQARRGSYGGAVGYLTGEGDLDTCIVIRSAYVENGIAQVQAGAGVVYDSDPQAEADETRGKAQAVISAILYAHQGKE
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: SYA_PSEF5
Sequence: MKSAEIREAFLRFFEEQGHTRVASSSLIPGNDPTLLFTNAGMNQFKDCFLGQEKRAYTRAVSSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTSDKWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPYASDNFWTMGDTGPCGPCTEIFYDHGADIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERISAVLQHVHSNYEIDLFQSLLDAAAKAIGCTNDAQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRACRHGNKLGAKGSFFYQIVAALVAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLKILEQDLAELKGSVVPGDVVFKLYDTYGFPMDLTGDIARERNLTLDEEGFEREMEAQRVRARSASSFGMDYNSLVKVDVATEFTGYHATSGSAKVVALYKEGQSVDMLSEGEEGVVVLDQTPFYAESGGQIGDCGYLQAGNARFDVRDTTKTGGAFLHHGVLAKGSLTVGAPVETQVDAQVRHATSLNHSATHLLHAALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAIKPEQIKALEDIVNAEIRKNTPVETEETDIDTAKKKGAMALFGEKYGDSVRVLSMGGDFSVELCGGIHANRTGDIGLLKITSEGGVASGVRRIEAVTGAAALAYLNAAEEQLKEAATLVKGSRDNLIDKLSAVLERNRLLEKQLEQLQAKAASAAGDDLSAQAADVKGVKVLAARLDGQDGKALLALVDQLKNKLGRAVILLGSVHEEKVVLVAGVTKDLTGQLKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDAAALDAALALTVPFVEQGI
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_DROME
Sequence: MKIGLCAFSGYKIYPGHGKTMVKIDGKSFTFLDKKCERSYLMKRNPRKVTWTVLYRRKHRKGIEEEASKKRTRRTQKFQRAIVGASLAEILAKRNMKPEVRKAQRDQAIKVAKEQKRAVKAAKKAAAPAPAKKSAPKQKAAKVTQKAAPRVGGKR
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.