PharMolix/UniProtQA huggingface dataset:
Protein: HIS8_LEPBJ
Sequence: MIQFQPVLGSLKSYEAGKPIELVVREFGIDPDQIIKLGSNENPFGCAQPVVEAVQKAASKMPYYPDDSYLELKTALASKFDLTPDRIILGNGSDQVLDFACRCVLGPGDSILINRITFAMYRIYALQCGAKVHSTETVLHDLNAFLDLAKSIRPKIIFLCTPSNPIGDALFKSDVYDFLRQIPSNTLVVIDAAYMEFGKKKDSNTFISAKEVTDLFPNVFYTGTFSKAYGLGGMRIGYGIGSKELISNLYKMRPPFNVANLSALAATEALKNESHVESYLDNNLKEMKRYEKFAAEQSVEFIDSYANFITFFARKRGKSSTEISQSLLKQGIILRNLRSYDLNAIRITIGKPQQNDRVLTALNQEFS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PROA_STRPM
Sequence: MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTLLAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNLDGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKLIRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVPVIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLEKAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQHTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHARGPMGLEALTSTKFYINGDGHIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_SACEN
Sequence: MSSPPRGEVAARLEPVVAEAVSAAGFDLEELDVQQAGRRRLVKVVVDAEEGVGLDEISEISRAVSKVLDAHEHVLAGSYTLEVTSPGVDRPLTRPRHWRRARYRLVRVRLADGSDLVVRVGEADDEGVVVLADGEIRTLAYRDVERAVVEVEFQQPPAEDLVRLERAADGAPERGGDRGDTEESR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BACHK
Sequence: MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL3_BRASB
Sequence: MRSGVIAQKVGMTRVFTETGEHIPVTVLKLGNCQVVGHRTTEKNGYVALQLGSGSRKTVYMPKAERGQFAVAKVEPKRKVAEFRVSEDSLIPVGAEILADHFVVGQFVDVTGTTVGKGFAGGMKRWNFGGLRATHGVSISHRSIGSTGGRQDPGKTWKNKKMPGHMGVDRVTTLNLRVVQTDVERGLILVEGAVPGSKGGWISVRDAVKKPLPKEAPKPGKFKVAGEQAAEAPAVQEGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GKAP1_XENTR
Sequence: MASAVVSMVPTTASRFALLQVDSSSDSDSEKARGAHATGKARSGSAAKGKSKGNEKKKEKRRKKKEQQQSEANELRNLAFKKIPSKPSQGIGGALQEHSTHNVPKEYQEDDWQQWQQRDEQLTSDMFEADLEKALMLSKLEYEESKDNGNEVNGVPQSKKVNKKDKRRNNQGKDKPLTVPLKDFQLEDQQAKKQEELKSPAMPQDRGFFNKLEEDVTKIILKEKRKEHSSDVTESFSTPDYSMEPALKDGKTEVLKQEIEKKEAELKQMKSIISQWEAKYREVKARNSQLLKMLQEGEMKDKAEILLQVDELLSIKNELTLQVTTLHAALEQERSKVKVLQAEQVKYQGGKKSKKNPESEHGR
What is the function of this protein?
May play a role in the regulation of insulin-dependent IRS1 tyrosine phosphorylation in adipocytes.
What are the official names of this protein?
G kinase-anchoring protein 1.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: SYV_SALTY
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESKESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWQWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETILGDTGVAVNPEDPRYQSLIGKFVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAEVFDTKGEESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDNDGNVYVGRTEDEVRQENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQMAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEEQDCGFNGGEMTLSLADRWILAEFNQTVKAYRDALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMTGGSESELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVICGITADTIMLQPFPEYNAAQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSEEAVRRVNDNRSFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKDDELARLAKEVAKIEGEIARIEGKLSNEGFVARAPEAVIAKEREKLDGYAEAKAKLIEQQAVISAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPB3_CAEBR
Sequence: MNRNCASPEEGGTTEQLVKEASDIVERDGFENKKKPPTLKLEHVEVVGEKSPTPATVYDLFKKYKKPDIVTNSNGDDMNVGFDQLSSDEKNGFLRKLQMLTVSSRKSVKVVGESTPSSAGRLLKKFAPSRKPTEKISVDEPPSRFNFFGRSTKKLSDSDRPSSLPKKKSARRLLFGKEEQKPEPEVVKNRVLPAMTSQQSAKGAPIPINKPYRYQGPRGSLETPTDSPAKISSNSSSSSPIPPVPTRNHFTSMNEESPSKKRTFSRQGLSNRDNLSNGSWHGELPPRDYTSPTFSRKIFVGGVPWDITEAALKDSFGEFGSCAVEWPGQEARYRSGQSNIAPLTNLRNQSKYAGQAATGYVYMIFEDERAVASLLHECSQEIGGAGEWYFKIRAQRSKSTEIRQVQIIPWVTSDSMFCEDESLLETGIEPKRTVFVGALHGMMTAQVLHWIMEDCFGSVECVQLDTDKFKYPIGSGRVTFREHGAYFKAIEMGYLHVHTSKFRKRVQIDPFLESTSCMVCTTESAQCFCRNRNCFKYYCHTCWAIDHGKDNADDVHVPVIVPSSASKAYAGPHRRPHLTSNSLSKSHGCSTNNQLSHVLSPGFPMIVGGPSQTLSALYGYIQNNQQMMLTPAVYETPMTPPSNESNAKRRSFTEFQNPAIFFNPSSMMTPQKSATCSETPVPAFFTNSAAFLTPNSNYYGSPNHSSSNISQSPQQYYGANLYYGYMPPQVAYDGSTNGSKLSPIHVPHIPNYQ
What is the function of this protein?
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 3.
Protein: SYS_BORAP
Sequence: MLDLKFIRDNLDLVKRSIKARGLVLDIDKLIYLDDKRKKIITKIGELNAKRNENSSKMRENLDKVLKISLIETGKILKKQLIDLEEELERVSFDFDLENKRVPNILSPDVPIGNSEEDNFEIKKVGIIPRFDFKPKDHLELGRDLDLLDFDRAREVSGSKFYYLKNEAVFLEIALINFSLNKLREKGFNVFITPDVAREFIVDGIGFNPRGNESNIYKIEDTDKYLVGTSEITLGGYYYNKIIDLTLPIKMAGFSHCFRKEAGAYGQLSKGLYRVHQFSKVEMFCFCKAEESSIIHDEFLSIQEQIFTELEIPYRVLNICSFDLGSPAYKKYDIEAWMPGRDGKGGYGEITSTSNCTDYQSRRLKIRYKDQDGQNKFAHMVNGTAIATTRVIISILENFQDEKGGVKIPKSLVKYTGFDYIPFKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC4_HUMAN
Sequence: MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  This subunit may be involved in the elongation of the multiprimed DNA template.
What are the official names of this protein?
Replication factor C subunit 4, Activator 1 37 kDa subunit, A1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37 kDa subunit, RF-C 37 kDa subunit, RFC37.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPF_BACCR
Sequence: MKICGITDVETAKSACEYGADALGFVFAESKREITPKRAEEIIQELPANVLKIGVFVNESVEVIQKIADECGLTHVQLHGDEDNYQIRRLNIPSIKSLGVTSESDMKNAQGYEADYILFDSPKEKFHGGNGKTFSWELLRDMPKELRKKMILAGGLNALNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RS19_CUPTR
Sequence: MTRSAKKGPFCDAHLLKKVEVATSGKDKKPIKTWSRRSTILPEFIGLTIAVHNGRQHVPVYVTENMVGHKLGEFAITRTFKGHAADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PAFC_MYCTO
Sequence: MSALSTRLVRLLNMVPYFQANPRITRAEAAAELGVTAKQLEEDLNQLWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALADIPGVVDPQAARSAIAKIAAAAGAVAAVAEQAPTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHSYLEAWSREAEGVRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFDGDLSLPSATLRVAPSASWMLEYYPIRELRQLPDGSCEVAMTYASEDWMTRLLLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
What is the function of this protein?
Part of the pafABC operon, but PafC does not seem to be involved in pupylation or substrate degradation.
What are the official names of this protein?
Protein PafC, Proteasome accessory factor C.
What is the protein family that this protein belongs to?
Belongs to the PafC family.
Protein: Y2306_ACISJ
Sequence: MDPKLLELLVCPVTKGPLTYDRERQELISRSARLAYPVRDGIPVLLENEARPLSDEELEQ
What are the official names of this protein?
UPF0434 protein Ajs_2306.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DCUP_PROA2
Sequence: MLKNDLFLRALKRQPVPRTPIWVMRQAGRYLPEYRAIREKTDFLTLCKTPELAAEVTIQPVDIIGVDAAIIFSDILVVNEAMGMDVQIIETKGIKLTPPIRSQVDIDRLIIPDIEEKLGYVMDAIRLTKKELDNRVPLIGFSGAAWTLFTYAVEGGGSKNYAFAKKMMYREPQMAHMLLSKISQVITEYLLMQVEAGADALQIFDSWASALSEDDYREFALPYIKESVQAIKTKYPDIPVIVFSKDCNTILSDIADTGCDAMGLGWNMDIAKARKELQDRVCIQGNMDPTVLYGTHDKIKAEAAKILKQFGQHTAESGHVFNLGHGILPDVDPANLKCLVDFVKEESPKYH
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACS2L_HUMAN
Sequence: MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLRKIITSEAQELGDTTTLEDPSIIAEILSVYQKCKDKQAAAK
What is the function of this protein?
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062).  Acetate is the preferred substrate (PubMed:16788062).  Can also utilize propionate with a much lower affinity (By similarity).  Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).  Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity).
What are the official names of this protein?
Acetyl-coenzyme A synthetase 2-like, mitochondrial, Acetate--CoA ligase 2, Acetyl-CoA synthetase 2, AceCS2, Acyl-CoA synthetase short-chain family member 1, Propionate--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: THI4_CHLRE
Sequence: MAIKMNLASSKVGAKASAKSVRGARLVARVAQPMSPSSAATAAADASMLARAGLPPTTTPYDDYKFAPIREAEVNRAMTRRYFKDMDEFAESDVVIVGAGSAGLACAFELGRIAPHLKVALMEQSVAPGGGAWLGGQLFSAMVVRKPAHEMLDALQVPYEDEGHYVVVRHAALLTSTLMSHVLKNPNVKLFNATAVEDLIVKPDPALGPGGRRVAGVVTNWSLVAQAHGTQSCMDPNVIEAGVVVSACGHDGPFGATGVKRLARLGMVPGGEVPGMGALDMEAAEGSIVNNTREVVPGMVLTGMELAEVDGSPRMGPTFGAMIVSGMRAAHMAVAALERRRALSAAAAEGAAAEAQA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, chloroplastic, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DERM_MOUSE
Sequence: MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV
What is the function of this protein?
Seems to mediate adhesion by cell surface integrin binding.  May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment.  Enhances TGFB1 activity (By similarity).  Inhibits cell proliferation.  Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
What are the official names of this protein?
Dermatopontin, Early quiescence protein 1, EQ-1, Tyrosine-rich acidic matrix protein, TRAMP.
What is the protein family that this protein belongs to?
Belongs to the dermatopontin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: YP025_YEAST
Sequence: MSSYLRHCSSRLPGKTCSRERNNFPLRLSGGISGEGIHPGFPIRMVQYAALALSTCCFSARDMDIDAPRGVSFLGIKWLAANQTRGMWDGSTISSPHTHVFRDISRTDSFFLFFFFFASHEIGTYLSAEESALDRYLSRFCGERESWDKCKKEMVGTKGQYTGPAVPSVPTTNLNDIGDPTKTVQ
What are the official names of this protein?
Putative uncharacterized protein YPL025C.
Protein: RL15_LACLS
Sequence: MELHSLKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKSRSGGGVRPGFEGGQTELFRRMPKRGFLNVNRKEYAIVNLETLNRLEDGATVSAETLVAAKIVKDVKSGVKVLANGELTAKNLTVKVAKVSAAAKAAIEAAGGSVEEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CUGA_CONCL
Sequence: MRCLSIFVLLVLLVSFAVAELDVEGEIVKQLLTRGTLKDADFWKRLEMQGCVCNANAKFCCGEGR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal16.1, Conotoxin Cal16a.
What are the subcellular locations of this protein?
Secreted.
Protein: DCTMQ_OLEA2
Sequence: MSDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRYIGVYLHEGAAAAVWTEEMARFIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWIIVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYIPYLVLPVSFGLMAVRLLQDLAGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAALATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGALPGGMALATIGTCMFFAAISGSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGVMIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAYSYWYSKKRGWKGEVRDRNLKTFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDCVVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIGTFMEALAAIVILTPILLPIVLKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANAKIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in the uptake of isethionate (2-hydroxyethanesulfonate), which is then catabolized by enzymes encoded by adjacent genes in the locus.  Thereby is involved in an anaerobic respiration pathway that converts the sulfonate isethionate to ammonia, acetate and sulfide.
What are the official names of this protein?
Isethionate TRAP transporter permease protein DctMQ, TRAP transporter, fused DctMQ subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TRAP transporter large permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEP2_HHV8P
Sequence: MASRRRKLRNFLNKECIWTVNPMSGDHIKVFNACTSISPVYDPELVTSYALSVPAYNVSVAILLHKVMGPCVAVGINGEMIMYVVSQCVSVRPVPGRDGMALIYFGQFLEEASGLRFPYIAPPPSREHVPDLTRQELVHTSQVVRRGDLTNCTMGLEFRNVNPFVWLGGGSVWLLFLGVDYMAFCPGVDGMPSLARVAALLTRCDHPDCVHCHGLRGHVNVFRGYCSAQSPGLSNICPCIKSCGTGNGVTRVTGNRNFLGLLFDPIVQSRVTALKITSHPTPTHVENVLTGVLDDGTLVPSSKAPWVLLRMSDYFSRLLIYECKKLKALGLRSY
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid.  Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
What are the official names of this protein?
Cytoplasmic envelopment protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Protein: NRDR_ACIF5
Sequence: MHCPFCAYADTRVVDSRLADDGGSVRRRRECPQCGQRFTTFERAELALPVVVKTDGRRESFNEEKLQRGLTRALSKRPVATARVDAAVRMIQRRIRERGEREIPARLIGELVMEALRDLDPVAYVRFASVYRRFEDVDAFSVEIARMKEAEVPDGGDDLNRGD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SYL_NITSB
Sequence: MQYDPKAIEQKWQNEWKEKNAFEPQENYSKEKMYVLSMFPYPSGRIHMGHVRNYTIGDAIARYYRKTGANVLHPIGWDAFGMPAENAAIKHKVHPKKWTYENIDYMRKELDALGLSFSHDREFATCDPLYSKWEQSFIIDMWNRGLLYRKKAAVNWCPHDKTVLANEQVIEGRCWRCDTEVVQKEIEQYFLKITDYAQELLEDLKKLEGNWPNQVIAMQRNWIGRSEGLEFRLHFDETSAKKAGIDGFEVFTTRPDTIYGVTYTALAPEHPVVKHLIETKQLSDEAVQKICTMQNQNARTRQQAEKEGLFLDLYVIHPLTKQKIPVWVANFVLAEYGSGAVMAVPAHDERDFEFAHKYNLPIKYIIKPKEGELDTTKAYTEPGILFDSGEFSGFESSEAKQKIIEYFEENGIGKRSVNYKLKDWLVSRQRYWGTPIPLIKCPKCGIVPEKKENLPVTLPEDVEITGEGNPLELHPTWKKTTCPKCGGEAERETDTLDTFVESSWYFLRYTTPRKYWEEVPFRKEDTDYWMPVDQYIGGIEHAILHLLYARFFTKVLRDLGYVNLDEPFKRLLTQGMVLKDGAKMSKSKGNTVDPDEIVAKFGADTARLFILFAAPPAKELEWSDSAVEGAYRFIKRFFERSQNAYKTKSLPKIDQKSLSKEEKEARKKVYEALQKSTDVYTKSFSFNTLIAASMEALNALNGQNNPDIWTEGYWVLTNILEPIIPHTCWEISHNLFERNNFTRLQLDPAALEEDSVTLAVTVNGKRRAEIEVPKDASKEEILAKAKEIAKKWIDGKTIVKEIVVPGRLVNIVVKG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_DESHY
Sequence: MPDVSQRIEALREQIEEANYQYYGLDQPTLSDAEYDALLQELIRLEKEHPEFLTPDSPSQRVGGYIAKEFPKVRHAEALLSLDNAFDAGDLLEFDRRVRALVAEVEYVVELKIDGLTVALTYEDGALVRGATRGDGEVGEEITANLKTIPAIPLRLRKQADRLDVRGEGYMPKGSFLRLNQEREEAGQPLFANPRNAAAGSLRQLDSRITAQRKLGYFAYQVLTPEEGELASQTAVLDYLKEQGFSVNPEYRVFSAIEEVIAYCGEMVEKRHNYPYDIDGLVIKVNDIAQQRELGFTAKSPRWAIAYKFPAEQVETVVEDIVIRVGRTGVLTPTAYLTPVFVAGSTVGRATLHNLDNIRAKDVRIGDHVLIQKAGDVIPEVVKILPEKRTGGERIFEMPELCPECQSPVIREEGEAAHRCTSITCPARQREAIIHFVSRNAMNIDGLGPAVIYQLLEAGLIKDAADLYALEYDALVPLERLGKKSAENLLKAIEDSKERGLAPLIFGLGIRHVGEKAGKILAQKYGTMEDLEKAQVEELQEIPDVGPAMAQSVAQFFQQESTHHFLNKLRQAGVVMSAQHSAKPQIFAGKSIVVTGSLQRWDRHYVETMIEEFGGKAASSVSKKTAFVVAGEKAGSKLAKAKELGIPVLSEEEFAELLP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: FPG_XANCP
Sequence: MPELPEVETTLRGLAPHLVGQRIHGVILRRPDLRWPIAAQIEQLLPGATITDVRRRAKYLLIDTDAGGSAVLHLGMSGSLRVLPGDTPPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQRDCETHELLASLGPEPLSAAFTGDYLHALACGRRAAVKTFLMDQAVVVGVGNIYAAESLHRAGISPLREAGKVSRERYRRLADAVKEILAYAIQRGGTTLRDFISPDGAPGYFEQELMVYGREGEACRHCGGELKHATIGQRATVWCAACQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GLSA_SHEON
Sequence: MPETALLEEVVDRVRPLLGQGKVANYIPALANIDPGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSKAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDTQGNSLAGTAMLEQLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RL10_RHOCS
Sequence: MDRTQKEATVAALNSSLQEAGLIIVTKQSGMTVAEVTDLRRKMRAAGCSFKVTKNRLARIALKGTQFETLDGFFKGPTAIAYSKDPVAAAKVAVDYAKTNDKFQIVGGGLPGLKLDSQGVDALSKLPSLNELRASLLGMIQTPATRIAGVLQAPGGQVARVLAAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.