PharMolix/UniProtQA huggingface dataset:
Protein: PYYA_DANRE
Sequence: MAVMLKPWTVVATVLICVLLCLGTFVDAYPPKPENPGDDAAPEELAKYYTALRHYINLITRQRYGKRSTSEDVMAELLFGDDTEHKQRSRYDDSFMW
What are the official names of this protein?
Peptide YY-A, Peptide YY, Peptide YYa.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: AZF2_ARATH
Sequence: MALEAMNTPTSSFTRIETKEDLMNDAVFIEPWLKRKRSKRQRSHSPSSSSSSPPRSRPKSQNQDLTEEEYLALCLLMLAKDQPSQTRFHQQSQSLTPPPESKNLPYKCNVCEKAFPSYQALGGHKASHRIKPPTVISTTADDSTAPTISIVAGEKHPIAASGKIHECSICHKVFPTGQALGGHKRCHYEGNLGGGGGGGSKSISHSGSVSSTVSEERSHRGFIDLNLPALPELSLHHNPIVDEEILSPLTGKKPLLLTDHDQVIKKEDLSLKI
What is the function of this protein?
Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions.  Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner.  Acts as a negative regulator of abscisic acid (ABA) signaling during seed germination.  Probably involved in jasmonate (JA) early signaling response.  May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade.  May act as a positive regulator of leaf senescence.  Has been identified as a suppressor of the deficiency of yeast snf4 mutant to grow on non-fermentable carbon source.
What are the official names of this protein?
Zinc finger protein AZF2, Zinc-finger protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRTS_PLAVN
Sequence: AICACCKVLNSNEKASCFSNKTFKGLGNAGGLPWKCNSVDMKHFVSVTSYVNENNYIRLKWKRDKYIKENNVKVNTDGIPSIDKLQNIVVMGKTSWESIPSKFKPLENRINIILSRTLKKENLAKEYSNVIIIKSVDELFPILKCIKYYKCFIIGGASVYKEFLDRNLIKKIYFTRINNAYT
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: GLMS_PHOLL
Sequence: MCGIVGAVAQRDIAEILIEGLRRLEYRGYDSAGLAVVDNEKNMFRLREVGKVQVLADEVDKQPVLGGTGIAHTRWATHGEPNEKNAHPHVSDYIAVVHNGIIENYEELRVQLIALGYQFISDTDTEVIAHLVHWEQKQGGTLLEAIQRVIPRLRGAYGAVIMDSRDPGTIIAARSGSPLVIGLGVGENFLASDQLALLPVTRRFIFLEEGDIAEVTRRTVRIFNTQGKPVEREQIESNIQYDAGDKGIYRHYMQKEIYEQPMAIKSTLERRLSHGQVDLSELGPNAAKLLAKVEHIQIVACGTSYNAGMVSRYWFEALAGIPCDVEIASEFRYRKSARRSGSLLITLSQSGETADTLAALRLSKELGYLTSLTVCNVAGSSLVRESDFALMTKAGAEIGVASTKAFTTQLTVLLMLVAYLGRLKGVDAEQEQEIVHALHALPSRIEGMLSKDKIIEVLAEDFSDKHHALFLGRGDQYPIAVEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIIVAPNNELLEKLKSNIEEVRARGGLLYVFADQDAGFTDSEGMKIIPLPHVEELIAPIFYTVPLQLLSYHVALIKGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNIH2_RAT
Sequence: MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.  Blocks CACNG8-mediated resensitization of AMPA receptors.
What are the official names of this protein?
Protein cornichon homolog 2, CNIH-2, Cornichon family AMPA receptor auxiliary protein 2, Cornichon-like protein.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Protein: RLMH_BACAH
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_STRP2
Sequence: MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQNRILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFVLTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLEGTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTRKTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHISARFLSKDISKLKKDAATIFENVHVVKDLEEVEI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: YQIA_ECO57
Sequence: MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYASCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL
What is the function of this protein?
Displays esterase activity toward palmitoyl-CoA and pNP-butyrate.
What are the official names of this protein?
Esterase YqiA.
Protein: KTHY_MYCPN
Sequence: MKQGVFVAIEGVDGAGKTVLLEAFKQRFPQSFLGFKTLFSREPGGTPLAEKIRALLLHEAMEPLTEAYLFAASRTEHVRQLIQPALQQKQLVIVDRFVWSSYAYQGLIKKVGLDVVKKLNADAVGDSMPDFTFIVDCDFETALNRMAKRGQDNLLDNTVKKQADFNTMRQYYHSLVDNKRVFLLDGQNQTGCLEQFIEQLSQCLTQPTLS
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GCSH_BACC7
Sequence: MSIPNNLRYSEEHEWVKTEGNEVVIGITHFAQSELGDIVFVELPEVGATIEADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ULAG_SALPA
Sequence: MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPGGNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_SODGM
Sequence: MSLDIKKYPTLVLADNPMELRQLPKESLVALCDELRQFLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDRIATIRQRNGLHPFPWRGESEYDQLSVGHSSTSISAGLGMAVAAEHEGLGRRTVCVIGDGAITAGMAFEAMNHAGDIKSDLLVVLNDNEMSISENVGALNNHLAQILSGKLYSTLREGGKKVLSGIPPIKELVKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVQGLVQTLKNMRAKKGPQLLHIMTKKGRGYAPAEKDPISWHAVPKFDPHMGTLPKSGDGCPTYSAIFGDWLCATAADDDKLMAITPAMREGSGMVAFSRQYPRQYFDVAIAEQHAVTFAAGLAIGGYHPVVAIYSTFLQRAYDQVIHDVAIQNLPVLFAIDRGGVVGADGQTHQGAFDLSYLRCIPNMVIMTPSDENECRLMLHTGYHYQAGPSTVRYPRGNSTGAPLTDLHELPLGKGVVHRQGAGVAILNFGTLLPQAEHAAQAINATLVDMRFVKPLDDTLISELAASHQALVTVEENAIMGGAGSGVNEYVMQQRLQVPVLNIGLPDHFIPQGSQEEIRADLGLDGAGIQRQIKDWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: POTA_MESFL
Sequence: MENNILELRNVTKDYDGKVVLKGIDLNIKEGEFITLLGPSGCGKTTTLRIVAGFEKPNSGQIMFEGKDLLPIPINKRQFNTIFQSYALFPHLNVFDNIAFGLRTKKTKKDILQREVLKQIRQVGLEGFEDRNINDLSGGQKQRVAIARALVMKPKVLLLDEPLAALDVQLRQHMREELKRLQREIGITFLMVSHDQEEALSISDRVVVMNEGSIQQIGTPEDIYNEPENLWVAKFIGQSNIIEDGIFIEDNKVQIDGKTFVCDDTNFGENEKSIDIVIRPEDIEIKKTNAGFFNGTVMHTTFKGVHWELLVETTKKRIWKIHTTQAFKVDDKVSIKWNDEAIHVMWKEVE
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TEFM_RAT
Sequence: MAWRANLACLIKAGGRTRWFPLPEYLSMSPVLHNTCSRRKSTAPEKLAASVAACDTNGKEPGTALGRLYSPEQQASILHVLNTASDKELEAFRLLRGRKSVNIVEHRKKFGPFQSLESLIGVPLIQYKTAVEVCNSILCPENRRRKKSQEKWVLRKFIKPGVEKERLKAVNSIVSIVFGTRRIAWAHLDRKPTVLDWQQAECWKLTNKTYPSSFYLEEISSVVSKIPKADLYILEKSGLSIQNTSLFPILLHFLITEAMLYALLNKTFAKDGQHRVLSINRNAVGKHFDLMIGDTRTSGRELVKQFLSESVLKEQPRVFFPRELAVQYRQKIVKSSHRIEELYDSLLQAVAFYELVFGSGSELKC
What is the function of this protein?
Transcription elongation factor which increases mitochondrial RNA polymerase processivity.  Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity).
What are the official names of this protein?
Transcription elongation factor, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TEFM family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Protein: TSAB2_COMTE
Sequence: MSADVPVTVAAVRAVARDVLALELRHANGQPLPGASAGAHIDLALPNGLVRQYSLVNATGQATMDCYQVAVGWDANSRGGSVWIHEKLKVGQALRVSAPRNLFEMAPEHRRVLLLAGGIGVTPIYAMAQACAQQGVDVELWASARSAPRLAYLEELKALLGQRLHLHADDEQGGPMNLTERLATQRWDAVYACGPAPMLDALTAATAHWAPGSVRMERFKGAEQPASERQPFELVLQRAGLSTTVDAHESVLDAMERVGVDFPWSCREGICGTCEAPVLEGEVQHLDYVLSPEERAEQRRMMVCVSRCGGGRLVLDI
What is the function of this protein?
Involved in the toluene-4-sulfonate degradation pathway.
What are the official names of this protein?
Putative toluene-4-sulfonate monooxygenase system reductase subunit TsaB2, Toluenesulfonate methyl-monooxygenase reductase component TsaB2.
Protein: ARAA_OPITP
Sequence: MKLLATPEIWFVCGSQHLYGPGPLKQVAANAQKVAAGLAASKKIPLKIVFKALLTTPDEITNLCIEANSDANCAGLILWMHTFSPAKMWIRGLSTLKKPFCHLHTQFNRDLPWGDIDMDFMNLNQAAHGDREAGFLHTRLRLNRKVVVGHWSDAEVQERIGAWVRAARAWHDWQGAKFARFGDNMRFVAVTEGDKVAAELRFGFSTNGYGVGDLVAKVASEGINDRHVDELCAEYEKRYAVAKELRRGGKRHDSLRYGARIELGLRTFLEEGSFKGFTTTFEDLHGLRQLPGLAVQRLMADGYGFGAEGDWKTAALLRAMKVMGEGLDGGTSFMEDYTYHMNPKGHQVLGAHMLEICSTIAATKPSLEIHPLGIGGKEDPVRLVFDAPAGPALNASLIDMGNRFRLLVNEVTAVKTPKLPKLPVARAVWECQPDFKTACAAWIYAGGAHHTGYSYSVTTEMLEDFANIAGIELAVINADTKLGEFKQTLRNNEVYYHLAQGIRV
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MQO_MYCBP
Sequence: MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RIMP_BACAA
Sequence: MDKKVTEVVEAFAQPIVEELNLELVDVEYVKEGQDWFLRVFIDSEKGVDIEECGAVSERLSEALDKEDPIPHLYFLDVSSPGAERPLKKEKDFQQAVGKQVAIKTYEPIDGEKMFEGKMLSYDGTTITLLLTIKTRKKEIQIPMDKVANARLAVTF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4E_PICTO
Sequence: MITKTKIMMAPRKLKIARKSRFWAVNSLPGSHKKDSSIPLLIALRDYLKLGDKEREITRILTNSLVMVDGKVVKERRRGIGFMDTLTVSGNDYLVSYDRKGKLVILPKPGETKGLKLLRVKGKTYVKGGRIQISFHDGSTMVTDRKDIKNGDSVLVKIPKKEIVDVLKFAPGNRVFITGGSHVGEIATIKSIEIKSSSGENMVHMNEGFSTVSSYVFVMGSPKYTFSMPEAIAE
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: ATPA_BARBK
Sequence: MDIRPSEISKILKEQIKNFDQEAEFSEIGWVLSVGDGIARVYGLDNVQAGEMVSFSNGVQGMALNLEMDNVGVVIFGSDRDIREGDTVKRLGSIVDVPVGPELLGRVVDALGNPIDGKGPLNAKNRRRVDVKAPGIIPRQSVHEPMSTGLKAIDALIPIGRGQRELVIGDRQTGKTAILLDTFLNQKPFHENEAGSDQDKVYCIYVAIGQKRSTVAQFVKVLEERGALDYSIIVAATASDPAPMQFIAPLAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNADNGSGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKTEEQVVTIFAGVNGYLDALAVSDVGRFERGLLALLRSDHQELLNAIASQKQITDELKGKLVAILDRYAKNFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UCSM_ACRSP
Sequence: MKHADPLRADTLGTAPLSQAIEAHHHGKEREAHRQSLSSVPGDTVVEAPEKVVDLEINSVDNDKEHHRAPTRDEIQTLRKVPGSIPATAYLLCFVDFAERASWFGARSVSSNFMQFPLPEGGNGAGAPPSGSELPAGALGHGQRFSVALGLVFSFLSYVIPIFGAWLAEAKVGRYRTILIGVLIGGVAHIIMIAGAVPSILQAGKGTAPFLVSLFLLALGAGLFRPNVSPTVLDQHRHYQPFVKELPSGENVIIDPEATMQRIMLIFYALINVGAFYSLATVYSEKLVGYWLAFLLPGIIYLLLPLMLWYLNDKLIKVPPDGGALTKFWKILTVSLVENKGMVWKKGFFDRVQPGALLQKYPSSGPVKWTSKDVEDVKRTLVACEIFLYFPIYHLNDGGVGTILPSQGAAMLKKGVPNDLLGNFNPITIMITVPVLTYIVYPALRKSNIKFGRISRITLGFWLAVISGLVSSLVQWRIYKTSPCGYHATTCPEVAPVSIWWQLPSYVLGALSECFSNVTGYELAYARSPPGMRSLVVSLFLFSTALSSALGLILTPAIVDPHLVWVWAGPTIALAVQTVIFWVRHRKYNDDEFMIEGDE
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of UCS1025A, a member of the pyrrolizidinone family that acts as a strong telomerase inhibitor and displays potent antibacterial and antitumor properties (PubMed:29373009).  These compounds share a hemiaminal-containing pyrrolizidinone core fused with a gamma-lactone, giving a furopyrrolizidine that is connected to a decalin fragment (PubMed:29373009).
What are the official names of this protein?
MFS-type transporter ucsM, UCS1025A pyrrolizidinone biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y9645_CAMJU
Sequence: MVVQMDIYDLMKQVNEWVKEILQDNYVGVYFHGSLRLGSFNPNKSDLDFIIVVKEKIDNEIKQLIWDKMLENEQLFPKKGFEFSVVLEDNCRNIKHPIPYELHGSRDWIERYKEDKTIVINDDYKVDPDLASHFNVINVPNDKMDFGKPSKEVFSKVPKEYIIDSNYSDTLDCVEEIVNNPVYCILNLCRFYALIRDDLTLSKYDGGKWALENMNSNYNDVIKNAMEDYLSDTNNSYDNTRLKEFAQEAISLINDCVDTNKIRK
What is the function of this protein?
Probably a nucleotidyltransferase, it does not confer spectinomycin or streptomyin resistance in situ or in E. coli.
What are the official names of this protein?
Probable nucleotidyltransferase, ORF11.
Protein: FB188_ARATH
Sequence: METRNRTIHLTDAIWTEILARLPLRIIARFKSVSKTWKSTIESVYFRRLFVSVHRKSSTSWSLMWYGQKDLVGFHGCETWGLPKSLSFYIPSSLCIIEGSSHGLVLISENDDDCCFVGNPVLQQWIKIPPPPVHSSVFGLVSRVDDDGFVLGFKVVKLAEVIVTNNYVSCSLSVFVYSSETGIWTCKTIHCPYQITNFGSFTLDGTIYFDHLSEPGVLVAYDFYSEISDQFWVIPLPDHPNHGFNSDFKGALTTSQGFVMYIRTLAQSSSNVFKAWRLNNDSTWQLLWKIGLPSLIGDYVPMAMHPFDSDIVHLWSQDHRHVVSWNLRTQKNRILGAEDNDEDHKDCYLNQPVCEECMDEICGCKASVRLLQLVLPRWMESVPCPPQVEMMNTASVISYVTSMQETMIRNWLHQ
What are the official names of this protein?
F-box protein At3g26010.
Protein: ATPE_SHIFL
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TA2R7_RAT
Sequence: MTYETDTTLMFVAVCEALVGILGNAFIALVNFMGWMKNRKITAIDLILSSLAMSRICLQCIILLDCIILVQYPDTYNRGKEMRIIDFFWTLTNHLSVWFATCLSIFYFFKIANFFHPLFLWIKWRIDKLILRTLLACLILSLCFSLPVTENLTDDFRRCVKTKERINSTLRCKLNKAGYASVKVNLNLVMLFPFSVSLVSFLLLILSLWRHTRQMQLNVTGYNDPSTTAHVKATKAVISFLVLFIVYCLAFLIATSSYFMPESELAVIWGELIALIYPSSHSFILILGNSKLKQASVRVLCRVKTMLKGRKY
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
What are the official names of this protein?
Taste receptor type 2 member 7, T2R7, Taste receptor type 2 member 6, T2R6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NRFA_MANSM
Sequence: MNGVIIVNILRKTLSSLAIVGLGFAMANSAVAEEKAMATHQQAQQLQQPAPETAAKRAPTKEELTPVNPNLKIEAANEKFAADFPRQYNSWAKTAEQTEFHKEVEDDPRMIVMWGGYAFAKEFNSPRGHIYAVTDVRNILRTGSPKDANGGPQPMACWTCKGPDVPRLIAEWGEEGYFSGKWAKGGAEVVNSIGCADCHDTQSQDFKDGKPALRVARPHVLRALDTVGKTFATSDRTDQRAGVCANCHVEYYFDKSTGANNVVFPWYKGRDVDSIEKYYDEIGFKDWEHSISKAPMLKAQHPDFETWSMGTHGKNGVTCVDCHMAKTQDKDGKVYTDHQVVGNPVKDNFQNTCARCHDQSQDTLIKTVEQHKADVREVMLKLEDQLVKSHFEAKTAWDNGATQEEMKDALQAIRHAQWRWDFAAASHGMHMHAPDVALKIIASGLDRVADARAKLAVILAKHGVQQPIQYPDISTAEKAWKVMGIDIEKERKEKEEFIKTVIPEWNKEAISKGLILTAPPTTPAK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DVNP5_HEMSX
Sequence: MAAMKKAMKVKKSAKKSAKKSGKKGGMKKKAKRVSKVARGKRAKSSVFRGTKERTSGGLTKNSLVKNKQGRVVSKKQSEHGKKIFKKHGLQKWIDAVTKARKALGIKGFQAVGGSSAKGKILLAKSRSFYKK
What is the function of this protein?
DNA-binding protein, which similarly to histones, may compact DNA into chromatin.
What are the official names of this protein?
Dinoflagellate viral nucleoprotein 5, DNVP5.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to condensed chromosomes (PubMed:23159597). Localizes upstream and downstream of transcription start sites of chromatin (PubMed:29670105).
Protein: ARGB_ALIF1
Sequence: MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLETIKKEGLRVTPKDQIGYITGALAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPELGNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNVNADQAAVAVATALDADLVLLSDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRSPEKLAELFIGNSIGTQFQPQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GB_HCMVA
Sequence: MESRIWCLVVCVNLCIVCLGAAVSSSSTSHATSSTHNGSHTSRTTSAQTRSVYSQHVTSSEAVSHRANETIYNTTLKYGDVVGVNTTKYPYRVCSMAQGTDLIRFERNIICTSMKPINEDLDEGIMVVYKRNIVAHTFKVRVYQKVLTFRRSYAYIYTTYLLGSNTEYVAPPMWEIHHINKFAQCYSSYSRVIGGTVFVAYHRDSYENKTMQLIPDDYSNTHSTRYVTVKDQWHSRGSTWLYRETCNLNCMLTITTARSKYPYHFFATSTGDVVYISPFYNGTNRNASYFGENADKFFIFPNYTIVSDFGRPNAAPETHRLVAFLERADSVISWDIQDEKNVTCQLTFWEASERTIRSEAEDSYHFSSAKMTATFLSKKQEVNMSDSALDCVRDEAINKLQQIFNTSYNQTYEKYGNVSVFETSGGLVVFWQGIKQKSLVELERLANRSSLNITHRTRRSTSDNNTTHLSSMESVHNLVYAQLQFTYDTLRGYINRALAQIAEAWCVDQRRTLEVFKELSKINPSAILSAIYNKPIAARFMGDVLGLASCVTINQTSVKVLRDMNVKESPGRCYSRPVVIFNFANSSYVQYGQLGEDNEILLGNHRTEECQLPSLKIFIAGNSAYEYVDYLFKRMIDLSSISTVDSMIALDIDPLENTDFRVLELYSQKELRSSNVFDLEEIMREFNSYKQRVKYVEDKVVDPLPPYLKGLDDLMSGLGAAGKAVGVAIGAVGGAVASVVEGVATFLKNPFGAFTIILVAIAVVIITYLIYTRQRRLCTQPLQNLFPYLVSADGTTVTSGSTKDTSLQAPPSYEESVYNSGRKGPGPPSSDASTAAPPYTNEQAYQMLLALARLDAEQRAQQNGTDSLDGQTGTQDKGQKPNLLDRLRHRKNGYRHLKDSDEEENV
What is the function of this protein?
Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells.  May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity.  Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors.  Participates also in the fusion of viral and cellular membranes leading to virus entry into the host cell.  Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).