PharMolix/UniProtQA huggingface dataset:
Protein: DGD_SALEP
Sequence: MKVSNLKITNVKTILTAPGGIDLAVVKIETNEPGLYGLGCATFTQRIFAVKSAIDEYMAPFLVGKDPTRIEDIWQSGVVSGYWRNGPIMNNALSGVDMALWDIKGKLAGMPVYDLLGGKCRDGIPLYCHTDGGDEVEVEDNIRARMEEGYQYVRCQMGMYGGAGTDDLKLIATQLARAKNIQPKRSPRSKTPGIYFDPDAYAKSVPRLFDHLRNKLGFGIEFIHDVHERVTPVTAINLAKTLEQYQLFYLEDPVAPENIDWLKMLRQQSSTPISMGELFVNVNEWKPLIDNRLIDYIRCHVSTIGGITPARKLAVYSELNGVRTAWHGPGDISPVGVCANMHLDLSSPNFGIQEYTPMNDALRDVFPGCPEIDHGYAYLNDKPGLGIDIDEAKAAKYPCEGGIPSWTMARTPDGTASRP
What is the function of this protein?
Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-galactonate dehydratase family member SEN1436, D-gluconate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: GUAA_CELJU
Sequence: MTHDIHAQRILILDFGSQYTQLIARRVREIGVFSEIRAWDMSDDEIRAYKPSGIILAGGPESTTEEEAPRAPEAVFALGVPVLGICYGMQTMAMQMGGWVESSAIREFGYAQIKAHGQSSLLQDIKDHVDQDGSALLDVWMSHGDKVTKMPEGFELMASTPSCPIAGMYNEAKKFYGVQFHPEVTHTLQGKRLFEHFVLQLCACEKLWTPANIVEDAIKKVREQVGTDKVLLGLSGGVDSSVVAALLHRAIGDQLTCVFVDNGLLRKNEGDQVMDMFAKNMGVRVIRADAEQLFLGKLAGVSDPEKKRKIIGGTFIDVFDTEATKLQEVKWLAQGTIYPDVIESAAAKTGKAHVIKSHHNVGGLPEDMAFKLVEPLRELFKDEVRAIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILREADAIFLEELRAADWYHKTSQAFAVFLPVKSVGVVGDGRRYEWVISLRAVETVDFMTARWAHLPYELLEKVSNRIINEISGVSRVCYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DJB12_MOUSE
Sequence: MESNKDEAERCISIALKAIQSNQPERALRFLEKAQRLYPTPRVSALIESLNQKPQSTGDHPQPTDTTHTTTKKAGGTETPSANGEAGGGESAKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCNRLSEVQASLHG
What is the function of this protein?
Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway.  Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities.  Can also act independently of HSPA8/Hsc70: together with DNAJB14, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers.  While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70.  When overexpressed, forms membranous structures together with DNAJB14 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear.
What are the official names of this protein?
DnaJ homolog subfamily B member 12, mDj10.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. DNAJB12/DNAJB14 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein. Note=Localizes to the endoplasmic reticulum membrane. When overexpressed, forms membranous structures in the nucleus.
Protein: HTXA_STUST
Sequence: MFAEQQREYLDKGYTKIESFFSAEEVAKILEDVKQIELGAIGVASDNETYQFEKKNGETTKLLRRVENPHLYFDAIDSLVRSEKIVDLLRHFLGENIRLHNSKINFKPPSGAPVQWHQDWAFYPHTNDDFLTLGIFLDETSEKNGAMACLPGSHKGKVYDHRNVETGEFCHAISRSNWDEALDPTEGELLTGPVGTVTLHHVRTLHGSGPNHSTIRRRFLLIGYAAADAWPLLGCGNYGDYESLMVSGRSTVFPRMVELPLTVPYPLSMYGDRIFESQRALTQKYY
What is the function of this protein?
Required for hypophosphite oxidation.
What are the official names of this protein?
Probable alpha-ketoglutarate-dependent hypophosphite dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: INS_APLCA
Sequence: MSKFLLQSHSANACLLTLLLTLASNLDISLANFEHSCNGYMRPHPRGLCGEDLHVIISNLCSSLGGNRRFLAKYMVKRDTENVNDKLRGILLNKKEAFSYLTKREASGSITCECCFNQCRIFELAQYCRLPDHFFSRISRTGRSNSGHAQLEDNFS
What is the function of this protein?
Involved in glucose metabolism.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSSK5_MOUSE
Sequence: MRSSSWRKSDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKRHTMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEHINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHNVGIVHRDLKCENILLDDQGFIKLTDFGFANWVGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLNLIRRGPIFRPGLSPECRDLIRGLLQLHPCERLDLQQVAAHCWMLPAEHMLSSALGAPREQDHSWSTVAPDNTEPDRDTRHARSKGSSSSSGRTSPRRPSLAQLCNTWKPAPEQ
What is the function of this protein?
May be involved in a signaling pathway during male germ cell development or mature sperm function.
What are the official names of this protein?
Testis-specific serine/threonine-protein kinase 5, TSK-5, TSSK-5, Testis-specific kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: CCA_SALPB
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDDDGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTAAGELEHLTQERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEYHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREELTKRRIAAVASWKEKRCPNPAN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: XYLG_BRUME
Sequence: MSEYLLEMRNIGKEFNGVKALDGIYLKVRAGECVGLCGENGAGKYTLMKVLSGVYPHGTWTGEIFWEGKELKASGIRDTEAAGIVIIHQELMMVPHLSVAENIFLGCEPTTGGFIDYDQMNARAAELLARLKINDINVALPVYHYSGGKQQLIEIAKAINKNAKLLILDEPTSALTASETRVLIDLIKDFKKQGMACVYISHKLDEVAEISDTVTVIRDGAHIATRPMSELTTPDIITMMVGREMKNLFPREPHDIGEVMFEARNISCWDVTNPDRKVVDDVSFALRRGEILGIAGLVGAGRTELVSSLFGVWPGACQGQVFLEGKEIKIRTPRDAVRQGICMVPEDRKRDGILPIMPVGHNMTISVLDRFSLRGLIDKDAELVAIQREILRLKVKTADPMLAIASLSGGNQQKAVLSKMMLPDPKVLILDEPTRGVDVGAKYEIYKLIFALARQGVSILMVSSEMPEVLGISDRVLVIGEGKLRGDFPNENLTQEKVLAAAIGKPATNAA
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RK22_CUSGR
Sequence: MTKKTKPETYVFSQNFPISADKARRVIDRIRGRSYEETLVILELLPYRAAYPIFKFVCFAASNASSTSTSKKENLFISKAEVNERPAIKKLKPRARGRSYPIKKATCHITIVLTDLSFYFNELVEPQQEKNLLTKLYLNLRGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid.
Protein: STY8_ARATH
Sequence: MTIKDESESCGSRAVVASPSQENPRHYRMKLDVYSEVLQRLQESNYEEATLPDFEDQLWLHFNRLPARYALDVKVERAEDVLTHQRLLKLAADPATRPVFEVRSVQVSPRISADSDPAVEEDAQSSHQPSGPGVLAPPTFGSSPNFEAITQGSKIVEDVDSVVNATLSTRPMHEITFSTIDKPKLLSQLTSLLGELGLNIQEAHAFSTVDGFSLDVFVVDGWSQEETDGLRDALSKEILKLKDQPGSKQKSISFFEHDKSSNELIPACIEIPTDGTDEWEIDVTQLKIEKKVASGSYGDLHRGTYCSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARVQIESGVMTAETGTYRWMAPEVIEHKPYNHKADVFSYAIVLWELLTGDIPYAFLTPLQAAVGVVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQIMKEVNVVV
What is the function of this protein?
Serine/threonine protein kinase that specifically phosphorylates chloroplast precursor proteins in the cytosol within the cleavable presequences (transit peptides).  May be part of a cytosolic regulatory network involved in chloroplast protein import.  Does not phosphorylate mitochondrion precursor proteins.  Specific for ATP and does not utilize other NTPs (PubMed:17090544, PubMed:16429265).  Plays a role in chloroplast biogenesis and differentiation in cotyledons, possibly through phosphorylation of chloroplast preproteins (PubMed:21799034).
What are the official names of this protein?
Serine/threonine-protein kinase STY8, Serine/threonine/tyrosine-protein kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: AKIB1_HUMAN
Sequence: MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIKAACLVQQKRQEFLASVARGVAPADSPEAPRRSFAGGTWDWEYLGFASPEEYAEFQYRRRHRQRRRGDVHSLLSNPPDPDEPSESTLDIPEGGSSSRRPGTSVVSSASMSVLHSSSLRDYTPASRSENQDSLQALSSLDEDDPNILLAIQLSLQESGLALDEETRDFLSNEASLGAIGTSLPSRLDSVPRNTDSPRAALSSSELLELGDSLMRLGAENDPFSTDTLSSHPLSEARSDFCPSSSDPDSAGQDPNINDNLLGNIMAWFHDMNPQSIALIPPATTEISADSQLPCIKDGSEGVKDVELVLPEDSMFEDASVSEGRGTQIEENPLEENILAGEAASQAGDSGNEAANRGDGSDVSSQTPQTSSDWLEQVHLV
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Ankyrin repeat and IBR domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
Protein: PTH_ECO24
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP7_MESAU
Sequence: MADDQNCAPELEKADPSGEDGVDAKPDRSSIISSILGKKKKNASACPVKTARDRVPTYLYRMDFEKMGKCIIINNKNFDKVTGMDVRNGTDKDAEALFKCFRSLGFDVVVYNDCSCAKMQDLLRKASEEDHSNSACFACVLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGVQADSGPINETDANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILDEHGKDLEIMQILTRVNDRVARHFESQCDDPCFNEKKQIPCMVSMLTKELYFGR
What is the function of this protein?
Thiol protease involved in different programmed cell death processes, such as apoptosis, pyroptosis or granzyme-mediated programmed cell death, by proteolytically cleaving target proteins.  Has a marked preference for Asp-Glu-Val-Asp (DEVD) consensus sequences, with some plasticity for alternate non-canonical sequences.  Its involvement in the different programmed cell death processes is probably determined by upstream proteases that activate CASP7.  Acts as an effector caspase involved in the execution phase of apoptosis: following cleavage and activation by initiator caspases (CASP8 and/or CASP9), mediates execution of apoptosis by catalyzing cleavage of proteins, such as CLSPN, PARP1, PTGES3 and YY1.  Compared to CASP3, acts as a minor executioner caspase and cleaves a limited set of target proteins.  Acts as a key regulator of the inflammatory response in response to bacterial infection by catalyzing cleavage and activation of the sphingomyelin phosphodiesterase SMPD1 in the extracellular milieu, thereby promoting membrane repair.  Regulates pyroptosis in intestinal epithelial cells: cleaved and activated by CASP1 in response to S. typhimurium infection, promoting its secretion to the extracellular milieu, where it catalyzes activation of SMPD1, generating ceramides that repair membranes and counteract the action of gasdermin-D (GSDMD) pores.  Regulates granzyme-mediated programmed cell death in hepatocytes: cleaved and activated by granzyme B (GZMB) in response to bacterial infection, promoting its secretion to the extracellular milieu, where it catalyzes activation of SMPD1, generating ceramides that repair membranes and counteract the action of perforin (PRF1) pores.  Following cleavage by CASP1 in response to inflammasome activation, catalyzes processing and inactivation of PARP1, alleviating the transcription repressor activity of PARP1.  Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction (By similarity).  Cleaves and activates sterol regulatory element binding proteins (SREBPs) (By similarity).  Cleaves phospholipid scramblase proteins XKR4, XKR8 and XKR9 (By similarity).
What are the official names of this protein?
Caspase-7, CASP-7, Apoptotic protease Mch-3, ICE-like apoptotic protease 3, ICE-LAP3, SREBP cleavage activity 2, SCA-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP1_CDDV1
Sequence: MVPELIAETAVTHFSDVYRPVQVVHKMIDKLKRKRDHSVKDVPQLQMANLSDNPTAQIIRAPKRTKLDAMLEGIMRVGDDMYDHAQPDNFSPLALIPVVNEKGHSPLSLIDLHAANEASNGLITGSGYAHTPYQADLADAHIIKIQQGTAYYEIDSQLMAQEFGDKSFGAFADEAYASERGYAIRTNPHTGNKEMFVAGTRNGWDWASNALEVTGASHILNNPVHSGVRAGEVGYMYATGNPVPPEYLGLAEKVADTIETPNGRIATPWRAKAQEFYSQVVVDEEVDVVYGHSRGGAIVADMQLPAAVTKIGLDSAMILADNKGMINFYQGGRGFDPGHPIAWFKSQVDMALGSTGENNIHLEVEGMHTHELWNHDSEDYMLEP
What are the official names of this protein?
Viral protein 1, VP1.
Protein: EPP_DROME
Sequence: MATLPPRKSQTPTRICISKQHLTPLQTLLQMGFPRHRAEKALASTGNRGVQIASDWLLAHVNDGTLDECAPREYIIYACPTGPFLQQLEEFWAKSRQMCGWNGAHNYVPHITLVSFFKAPDECSLQLSKALKQVVDMTGALLDRPLKLEPYMSQNFMGFFVAEEDANYLKRLALQYVKEVSNSIISDTYEQLDAIVACFPWCGAVSSGTRCIPRSSRSISLEPHVKSLHLTLAYQFPQAQFNALKALVETLDASCASNWELRLYSRDPRLATKQVQKVVYPHNPHETDELELRIGDYIYLNTEVVDSSSDGWAEGISWLTGSTGHLPVNYTERTAESDAWTLHRVVQLSKSVASSLTSAEDLDIVDGRSISTEPDDRQNTAHPDIIEGSSFEESEQSVEKYLRQTLKPCLELPSVQLLNSHNLTHQHNPNTPTIEITTNMSSSSTSMSKQPVDEILVEPPAAQPPRPDDTLSVHSDHSLHPGSLDASHAKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVGVYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYPSGVPDWLTKNELTEAKFDVDLDYEPVQPASELTARLKESTEQFYERNHDVILQLLEQTTGNILVVAHATTLDTCSRQLTGGVPRSTNELRQVIHKIPYCSLATVEQVDGVWKLVEPECLPVTHSKNPRFEWNALSAT
What is the function of this protein?
Steroid phosphatase that dephosphorylates ecdysteroids such as ecdysone 22-phosphate (E22P), 3-epi-ecdysone 22-phosphate (E22P) and 3-epi-ecdysone 2-phosphate (E2P) (PubMed:17348005).  Likely catalyzes the conversion of inactive phosphorylated ecdysteroids into their active forms (By similarity).  Shows high activity towards ecdysone 22-phosphate (E22P), but is also significantly active against 3-epi-ecdysone 22-phosphate (E22P) and 3-epi-ecdysone 2-phosphate (E2P) (PubMed:17348005).  Also displays acid phosphatase activity towards 4-nitrophenyl phosphate (pNNP) in vitro (PubMed:17348005).  Has no activity towards 3-epi-ecdysone 3-phosphate (E3P) (PubMed:17348005).
What are the official names of this protein?
Ecdysteroid-phosphate phosphatase, Protein UBASH3A homolog, Ubiquitin-associated and SH3 domain-containing protein.
Protein: CLPS_STRMK
Sequence: MPHESSPDSQHEHGVAVEAARPEVAPPPFYQVMLLNDDYTPMDFVVDVLQQFFSMDLDKATQVMLHVHTRGRGVCGVFTREVAETKVAQVNEYSRMNQHPLLCTMEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RL11_BREBN
Sequence: MAKKVIRVIKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTESEVGMIIPVEITVFEDRSFTFITKTPPAAVLLKKAAGIESGSGVPNKTKVATLKRDKVREIAELKRPDLNAASVEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: QUEC_PSEE4
Sequence: MTDKRAVILLSGGLDSATVVAMAKAEGYACYTMSFDYGQRHRAELDAAARVARDLGVVEHKVIGLNLNGIGGSALTDNSIDVPEAPGEGIPVTYVPARNTVFLSLALGWAEVLEARDIFIGVNAVDYSGYPDCRPEFVEAFERMANLATKAGVEGQGFRIQAPLQNLSKAQIVQAGIAQGVDYSLTVSCYQADDEGRACGKCDSCRLRADGFKAAGVEDPTRYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NORW_KLEP7
Sequence: MSDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLTLQSAGEFAEQYTLRLFPHTWVSDIDAENRLVKSHDNQWRYDKLVLATGATPFIPSVPGRELMLTLNSQREYGAAQSQLHDAKRVLIVGGGLIGCELAMDFCRAGKAVTVVDNSASVLAALMPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPETSLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLLAQAGELKLPPMLVKVKTPDLPLHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVVSEDKMKEAFALLKQLVS
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_CANGA
Sequence: MLKSRFKVVGKEALMASLPLEPSVPMCIRKGCLVSVMAGGAHGSGKTASLVIGHKWVNFWTNLARFRSWNSSLYHVLTTSGKENRALVAPNISRGSPWLSALKLVVSILSKNSKGITITDPQRSIYPLELDGTQDWNVWGRDSLIAFEQNDSLDIKPASLSSSLKRDALFSHSHKYQVVTGRGSVLLGGYGDIYSIDLKNSTDDIVINAQNILAVSGKGQTETMNAIENNPFIISHTAASNIPEFTSNVQELAAFEDPKQQQSQTIVQKTVKEAARASKAVWHWISYVYKKTVIFSNNNGHNITSPAFVKIKGPRTIIIQTSHETTQPVSVSTVDILPRTVENAIPEVVETPKAKSDSYINYATVQPDGNVTFRSVSNFNETIAERY
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUD21_ARATH
Sequence: MISLFISNFSNLSNLSPTFDNMNMNIPSKKIVPVPTPSEKVVSLVSRTGRDLQRYNTAGYRQVVGCVPYRYKKHGGGEIEVLLISAQKKGKGMLLPKGGWEIDESIEEAALRETIEEAGVTGQLEESLGKWQYKSKRHTMIHDGHMFPLLVSQQFEIWPESEFRQRKWVSLSEAIELCQNSWMREALEAFINRKCQTQ
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nudix hydrolase 21, chloroplastic, AtNUDT21.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCA_VIBVU
Sequence: MEVYLVGGAVRDKLLGIPVYDQDWVVVGATAEQMLNAGYSPVGKDFPVFLHPKTKQEYALARTERKTGQGYKGFECFFSPDVALEEDLLRRDLTINAIAMDSQGVLYDPYGGQQDLQNRILRHVSEAFVEDPLRVLRVARFAAKLAPLGFRVADETMQLMQSIVASGELSALTAERVWQEWHKSLLTPAPQQFLAVLRQCGALAVVLPEIDALFGVPQPEKWHPEIDTGIHTLLVAEQAAKLSSSAVVRFAAQVHDLGKGVTPPSEWPSHKMHCHTGLKLIKQLCERVRVPNEFRDLALMVCEQHSNIHRAAELKPQTMVKIFNKLDVWRKAERLNDILLCCQADHAGRQGLQDHPYPQAERIQLAYQAALSVEVQSIIQDGFKGPAIRDEQERRRTEAVKAALLNA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: NPD_VIBVY
Sequence: MNFPYRNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFARDPDLVQDFYNQRRKKLQDPNIEPNAAHLALGRLEAELDGQVTIVTQNIDNLHERGGNKNIIHMHGELLKSRCSVSNQVIEETGDILTGDLCHCCQMPSQMRPHVVWFGEMPLRMGEIYSALETADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAIESEFVEKRYGKASVEVPKLVEELLAHLESNVENA
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTN2_PIG
Sequence: MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAELEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKMTVKESATEEKLTPVVLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNTKGAGSGGKTTSGSPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELEATVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIACSLKDNATLLTQVQTTMRENLSTVEGNFANIDERMKKLGK
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.  In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (PubMed:25814576, PubMed:33734450, PubMed:36071160, PubMed:29420470).  Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis.  Involved in anchoring microtubules to centrosomes.  May play a role in synapse formation during brain development (By similarity).
What are the official names of this protein?
Dynactin subunit 2.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunit 2 family.