PharMolix/UniProtQA huggingface dataset:
Protein: TPIS_ROSS1
Sequence: MRTPLLAGNWKMYKTTGEARELVEGLLHGLGDVSDRKVLVCPPFTALHTVRDLVQGTPIALGAQDVYIEPQGAFTGAISPVMLRDLGCTYVIVGHSERRAIFGEGDELIGKKVRAALAHDLTPILCVGETKPQRDAGEAETIVVAQVRAALAGMTPDQIARIVIAYEPVWAIGTGDTATPADAQAMHVTIRQTLGELAGSDVADAINILYGGSVKPDNIDDLMAQPDIDGALVGGASLKADSFLRIVHFLPIQG
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTL_SALTI
Sequence: MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATFGIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQRA
What is the function of this protein?
A component of the bacterial microcompartment (BMC) shell dedicated to ethanolamine degradation (By similarity).  Forms a hexagonal trimer with 3 small channels and a large central pore that has been seen in both open and closed forms and is probably used for gated transport into and out of the BMC (By similarity).  Ethanolamine-binding by the small channels has been hypothesized to stabilize the EutL central pore in a closed (non-transporting) state.  An open pore is thought to be large enough to transport ATP and/or cobalamin (By similarity).
What are the official names of this protein?
Bacterial microcompartment shell protein EutL, BMC-T, Ethanolamine utilization protein EutL.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RLME_MYXXD
Sequence: MLGSPPDMGKPYRPKDHYFQKAKQEGLRARSAFKVDELIKRFPMVKKGHVVLDLGAAPGGFLQILADAVGPKGRVIGVDIVAIRPFSQPFVQTAVLDVLADDFDAKLTELHAGPFDAVISDMAPKTSGIKATDEARSLRLAGKALELAAARGRPGSSFVAKVFMGRDFEDFRNQIRALFEEVKVVRPEATRGASMEVYLVGLRRRAPEAPEAN
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX53_HUMAN
Sequence: MSHWAPEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMVGVVIGYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYNSESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPGQRRKEFYFLS
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX53, Cancer-associated gene protein, Cancer/testis antigen 26, CT26, DEAD box protein 53, DEAD box protein CAGE.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EF2_METM7
Sequence: MGRRAKMVEKVKTLMEKHDQIRNMGICAHIDHGKTTLSDNLLAGAGMISKELAGDQLALDFDEEEAARGITIYAANVSMVHEYGGKEYLINLIDTPGHVDFGGDVTRAMRAIDGAVVVCCAVEGVMPQTETVLRQALKEKVKPVLFINKVDRLINELKLTPEELQGRFMKIIAEVNKLIEKMAPEEFKKEWLCDVVTGKVAFGSAYNNWAISVPYMQRSGISFKDIIDYCEQEKQGELADKAPLHEVILDMAIKHLPNPLQAQKYRIPNIWKGDAESEIGKSMVACDPNGPLAGVVTKIIVDKHAGAISACRLFSGRIKQGDDLYLVGSKQKARAQQVSIFMGAERVQVPSISAGNICALTGLREATAGETVCSPSEILEPGFESLTHTSEPVITVAIEAKNTKDLPKLIEILRQIAREDNTVRVEINEETGEHLISGMGELHIEVITNTKIGRDGGIEVDVGEPIVVYRETITGTSPEIEGKSPNKHNKLYMIAEPMDESVYAAYVEGKIHDEDYKKKTTADGEARLVEAGLDKDQAKKVMSIYNGNMIVNMTRGIVQLDEARELIIEGFKEGVRNGPLAAEKVQGVKIRLVDATFHEDAIHRGPAQIIPAVRFGVRDAVAQAKPVLLEPMQSVYINTPQDYMGDGMKEINNRRGQILDMEQEGDMSIIKSSVPVAEMFGFAGAIRGATQGRCLWSVEFSGFERVPAELQPKIAKQIRDRKGLKSE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI214_OENEH
Sequence: MVNLVYVCMKINNSVVMVGLYYGFISAFSIGSSYLFLLRPRFLNDDPDAIEKKASETAGFFTGQLLIFISILYGPLHLALGRPHTILLLLAPYFFFHYLFSNSGQWPSQRFAFPLLTKSMRNRRFQLVFLNNLLFQLFSLSLLGRPMLTRLSYIYIFRCNNKMLFVLSSFVGWLIGHILVLKWAGLVFVWLLQVIRSKTMKYITCNVLIPATKYIIEKWRNSFVAGLIREILAMKQVESALVRIKNSKLLDDARWWIRGSSLISGLKINIRFYARLILRGFENVYVGAKFRQDMEHLFSIILFAIFLLYLDQTPLLYADPADKKLQLQRKLSNETQAARAEKKLEERLTKKFEAQRRAQRAAQRQALQEFKQGVVESYLAKQVAKDANQIQAQKDEKQIQAEQKARRIRAEQVVQYTFWLIEAQRREMEIEAARAMQEAYKGMLAAQEGYVEEGVQEKQEGFPEELISPSPIFHSEEREENPKLLILKEKISILKKKISILKKKISILKEKNDLFSFEIPIITSLFDPQKPLRPLRYIKTCAGVEKAVKNEMSQYFFYACRSDGKQRICFTYPPSLATFWEMIQRKMASRFPRIYAKAKWRALRWSAPGSYRQWISRNKKKKNSLSTEFQNRIKTLDKKKSLLNVLARRKRSSLLNVLARRKRSSLQNVLETRKRLCNYKTNKTKKEYLPEKEYLPEIADPFLTGALRGKSDPEVDDGGRKTSDLIKVVFLKNNITMATLRNKNDDDLREQKNAIALLSRMKNPVNKLHLLFVNERDYPFVKTLVNRINGPAVPKKKKKISKSKQKNVKSKQKNVKSKQKNVKSKQKNVKSKQNEIKRKVNEIKRKVNEIKRKQNESYPRGVKFGATPKTEINPHGIRFDAATIEKYSFATGYSYSPPSFDDILFHAFVTEPQRNKKAVIELEEEINKKVPRWSYQLIDELEQLEGAEGETQFSDHEIRILPFKRVAVFTEKDSKKRKPLIDEQGNFVRHRKTYAIRFLGHMSDFRRGLIKGSARQDRRKAYVCRTTQVNARSPLFALGPRTFLDGLVNLAVQVKFFYETRIKGEKIVDDDDDNEKDEFKVMIPDTKSIVAETREMLKQAGAEDGQSYEDVEDDIRIENVTEMWENIDYGQVIRTFILLLHIFLRKKVVFPAFIIGKNIARMLLLQATEWKIDFARLKRERYAICTYNGMKVSEKIAFDQFPPDWADDGIQILVTNPFYLKPWYRSKTRSIQKDPKKEKDPKKEKGPKKEPWYRFKTRFIQKDPKKEKGPKKEKGPKKEPWYRRFFFQKDPKKEKGPKKGKAQFEGDRGVRFLTSFGILTDRPFGDLITPDWGVFFNPIRNELKKKIRQFEKKHSIILSKRFRNVLKKTKKWFIKSFLFLKRARLKRHPIELSGGRETPEFTRSQKDIDNLKNEQDFRMSRNPRISESLLQGPVRALKDDSLPEEKVADPEKEPSDLDNELRAVWDEIDKVTKERKKIVFTPKPDSPDKLVQAKKNILKKLERIKSRRHKFYFLRIRKSYYVLLFFIKRISRNIKRIYLNPLERAISIRKIHPQRFFEFSKKMIEKSIGIGKTETNKETVYKTKKKKKKKNPFISIFKESLYDKDIRISENDIKLGDTWNGYKYKRKKATDTSDLASMSQAYVFYKLYQTQQTQLIHLDKLRYVLQYDGTSRFLKKELKDYFEAQELFHSKLKHKNSLNSGKNQWKNWLKAQHQYSVSPIIWNSLSPQKWRTKVNQERMDENTDLNKRYSNEKRKQFFEANSLDDEENVVETYLGQRAGDIKNSIKSYSYDLFSYQSINSEDKYVCINNKQKNSYNYNRRKVNLVDSPEGIALSNQFLVQNDLLDLYTFPDRKYVPWRLFPGSLIGGNDKDKDRFVKMWTATNSGNAVKYWTAANGNTSIKPGVFWTFQNSQRTKKQNPLFDWRGMNTELPNRCISDLKGWFFFSELLKLDLRYQVKPWILSKNLLFENLIFENQEENPNLIQNPIEDGRKNVIQNENENDPIEDGRQNVIQNENENAIQNLIDFFLEKKNSPKDTNQELHAQAKARIWDALVASLKQKREQKERKNKRIAQLIEKKKQKEIEKQKRKIEKQKRKKEKIENAKKKIENEKKKIETEEEKIEKEKRKKERKKEKLKKKVAKNIEKLKNKVAKNVAKNIEKLKKQRAKNIARMEEEDKKARKKRKRKVQVQENKIPYTAFGSDKWQRPIAEYPKSGDIRNFQVILPEDDDEDDEEDRLDELKLNAYELSRIQKITDEKRMKRNLLSSIKRERLKMEFSTRNNSLATIMLTHGIFSIEPLRISRQNQDASFLIYQLIKISLVEQLDPYDHNDSFELTEKYRARRNFFMPKTNAETMHKSDSDLFVPETILSTKRRRELRILISFYSRRGKRKNRIYKNPVFWKYVKNCGEVVDNSEKKKKKLIKSFLWPNYRLEDLACMNRYWFNAQNGSRFSMLRIRMYPRLKIR
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: NTPPA_ECOLI
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP (PubMed:24210219, PubMed:25658941, PubMed:28811554).  Can also hydrolyze TTP and the modified nucleotides 5-methyl-UTP (m(5)UTP), pseudo-UTP and 5-methyl-CTP (m(5)CTP).  Has weak activity with CTP (PubMed:24210219, PubMed:25658941).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids (PubMed:24210219, PubMed:25658941).  Important in maintenance of cell shape (PubMed:25658941).
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINJ_LACCD
Sequence: MAVVVALLINPVGLVFWLALGLTIWFAVNRTDRERRRYLRAIHPKHPEIGRFFWIGLVVGALVSLVMVIGRLQISLAALLALSGLTLVALLFSKWRFSPWWLGLASLAAVGQSGLLAEQHAANLAILVGLLWLTQAGLARFNRGDEIESPVIQQDRRQRQSAAFELRQLFWVPLILPVAVENVSNLPLLAVTVQSLTFVGLPLLLGATFMTPRDRAQTAWRRSWPWYGGAGGVLIVYGIVARTMTLPLLVSLVFPAVVSLVLVGGFIWQGRQVHLTVTLADQGVVLIGVVPHTPAAEMGLQPGDRVLACNHHSVNNSRELYDAIQKEPTYCRLRLRQADGELRLAETAIFAGAPHELGMILFPEETA
What is the function of this protein?
The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle.  MinJ acts as a bridge between DivIVA and MinD.  May modulate activity and localization of MinD and MinC through direct interaction with MinD (By similarity).
What are the official names of this protein?
Probable cell division topological determinant MinJ.
What is the protein family that this protein belongs to?
Belongs to the MinJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGSA_RICCN
Sequence: MRIDKNLPNYLTIARIMVIPVIILVFYINNSLARTLGALLFVLASITDFFDGYIARKYNLVTSFGKMFDPIADKLLVGCVIIMLLKKDNVDEIPCLLILAREFLVSGLREFLALVKVSVPVSRLAKVKTFLQMFALSILILGSKGSGIIYLDIVGEIILWIAAFLTIITGYSYFKACKKYF
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLYA_FINM2
Sequence: MNNCRQNLENFDPEVFGYLNDEIKRQEEHIELIASENFVSKAVLETMGTELTNKYAEGYPGKRYYGGCEHVDKIEQLAIDRLKKLFNADHANVQPHCGANANIAVYVAVLKPGDTVLGMRLTEGGHLTHGSPVNMSGKFYNFVDYGVDPETGTIDYENVRELALKHKPKLIVAGASAYPRIIDFKKFREIADEVGAYLMVDMAHIAGLVATGDHPSPVPYADFVTTTTHKTLRGPRGGAILCKEEHKKLLDKSVFPGFQGGPLEHIIAAKAVCFKEDLQPEFKEYTHQILKNAKAMEKVFLDNDVRLVSGGTDNHLLLIDCRSFGMTGKEAENVLSEVNITTNKNTIPNDPETPFVTSGIRIGTPAITTRGLKEAEATKVAEFMIDALKKRRPAEEIKNDVVELMKQFPINR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL_PSEPU
Sequence: MEMLKFGKFAALALAMAVAVGCSSKGGDNAGEGAAVDPNAGYGANTGAVDGSLSEEAALRAITTFYFEYDSSDLKPEAMRALDVHAKDLKANGNRVVLEGNTDERGTREYNMALGERRAKAVQRYLVLQGVSPAQLELVSYGEERPVATGNDEQSWAQNRRVELRK
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Peptidoglycan-associated lipoprotein, PAL.
What is the protein family that this protein belongs to?
Belongs to the Pal lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RUVB_LISMO
Sequence: MDERIISSETVDAEEVSFETSLRPQNLSQYIGQDKVKNNLTVFIEAATLRNEALDHVLLYGPPGLGKTTLAMVIASEMGSQIKTTSGPAIERPGDLATILTSLEPGDVLFIDEIHRLSRAIEEILYPAMEDYCLDIVIGTGPTARSVRLDLPPFTLIGATTRAGLLSAPLRDRFGVIDHLEFYTEEQLTEIVLRTSNILDTKIDDLGAREIARRSRGTPRIANRLLKRVRDFAQVRGNGTVTEKLAKEALTLLQVDPRGLDTIDQKLLHTIIQSFRGGPVGLDTIAASIGEERETIEDMQEPYLLQIGFLQRTPRGRIVTETAYNHLGISYEKEV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PPS1_DROFU
Sequence: DVPSANANANNQRTAAAKPQANAEASS
What is the function of this protein?
Represses female sexual receptivity and stimulates oviposition.  This peptide has a low activity.
What are the official names of this protein?
Paragonial peptide PS-1, Paragonial peptide C.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_XANOR
Sequence: MARKINCYIKLQVKAGQANPAPPVGPALGQRGLNIMEFCKAFNAATSKLEPGLPTPVIITAYSDRTFTFVTKSTPASVLLKKAAGVTSGSKRPNTDKVGKVTRKQLEEIVKVKEADLTAADLEAAVRTIAGSARSMGLTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TAT_HV2EH
Sequence: MEIPLKEQESSLNSSSGHSSSTSEGVANTQGLDNRGEEILSQLYRPLKACSNTCYCKKCSYHCQLCFLKKGLGICYERSRKRSSKRAKTTTSSAPNESLSARTGDSQPTKKQKKEVETTRATDLGPGRSNTSTSRFAN
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: APAG_PSEMY
Sequence: MSDPRYQIDVSVTTRYLAAQSQPEQNRYAFSYTVTIVNNGQLPAKLLSRHWIITDGDGRVQEVRGAGVVGQQPDIAPGASHTYSSGTVMATQVGIMQGSYQMLAEDGKRFDATIAPFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: SSN8_ASPCL
Sequence: MAANYWASTQRRHWLFTRERLAEIREAFRERHKLAHSQFPLPDQRLLNIYFSQQLIKLGKRMSTRQQALATAQVYIKRFYTKNEIRHTNPYLVLTTAFYLACKMEECPQHIRFVVGEARSLWPEFITPDVSKLGECEFSLISEMNSQLIVHHPYRTLSGLQSELSLTSDEVALAWSVINDHYLTDLPLLYSPHVIAVMAVMVAVVFKPGPGNFHGSAAPVLAGAMRDGGMNMLAALGDKSGNEPPPKVQKLINWLAESEVDIKAVIECTQELVSLYEVWEQYSEKNCKELLGRMVKTKHLDK
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_DESAH
Sequence: MFITLEGIEGSGKTTQIKPLVDCLGQNGYEAVVTREPGATVIGKKIRAILLDPGNSGMSDLCELFLYGADRAQHLSEVIIPALGAGKTVVCDRFTDATTVYQGAARGISKELIDIIHSVVVKDLCPDLTILFDLDPETGLARTVKALTDGERTLDESRFERETLEFHERVRQGYLALAAAEQDRFLVVDARGTQEQVFTEIVSGINRRLGIDLVGIDSAMIDPRVKG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KITH_BACAA
Sequence: MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFKHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYEPRCRHCHAVPTKQR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDA_NITMS
Sequence: MSQEQAEQLMQQMQMLETYFADLSQRENTFLGVFREATAAIESIKSLSKNPESDTLVPIGLGTYVPTKISSDSKIILNIGAGVAVEKDFPSAINYLEERIKEIEIAIQDTAAKKQDAAQRLEQGKAQVNQLMQAMQQSGQPPKSG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_STRP3
Sequence: MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PROA_SINMW
Sequence: MLETVENGDDVKAIMLEIGRRAKAAARPLAVASAERKHAALVAVAGALGARAAEILAANALDLENARESGVANAFIDRLTLTESRIRDMADGIRAIAELKDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSFHSSRAIHACLVEGLKAAGLPADAIQMVPVADRAAVGAMLTGLNGAVDVIVPRGGKSLVARVQNEARVPVFAHLEGLCHIYVDASADLAMATQIVVNAKMRRTGICGAAETLLIDRNAAEKLARPLIEALVEAGCEVRAESSLSSVMPGLKSATDEDWATEYLDAIISVKLVDGISGAIEHINIWSSAHTEAIIAEEPRVVERFFSEIDSAILLHNASTQFADGGEFGMGGEIGIATGKMHARGPVGVEQLTSFKYRVRGTGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ECO7I
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTINIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PROA_ROSCS
Sequence: MTNLEEIGARARAAGRRLALMPTERKNAALEAIAAALLDEANAAEVLAANADDVAAGRDAGLSPALIDRMTLTPQRLAAIAADTRTVAGLPDPVGERFDATVLENGLRVHKRRVPLGVVGVIYEARPNVTVDVAALCLKSGNAAILRGGKEITRSCAALTRLIQNALAQTGLPADAIQVIDNPDRALVEQLLRLDRYVDVIIPRGGAGLHRFCREKASIPVITGGIGVCHIYVDQAADLEMVVPIVHNAKVQRPSVCNALDTLLVHRAVAAEMLPAVARDLLASNVELRVDEEAMALLRAAGFDTPQIVPAQESDFGVEFMALILSIRVVAGLDEALEHIARFGDHSDAIITRDPATAEAFVQAVDSSAVFVNASTRFNDGGQLGLGAEIAISTQKLHARGPMALRELTSYKWVVEGDGHVRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_STRP7
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVRVRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: AMT_CORGL
Sequence: MDPSDLAWILAAFALVSLMFPGLSLLYGGMLGGQHVLNTFMMVMSSLGIISLVYIIYGHGLVLGNSIGGWGIIGNPLEYFGFRNIMEDDGTGDLMWAGFYILFAAISLALVSSGAAGRMRFGAWLVFGVLWFTFVYAPLAHWVFAIDDPESGYVGGWMKNVLEFHDFAGGTAVHMNAGASGLALAIVLGRRHSMAVRPHNLPLILIGAGLIVAGWFGFNGGTAGGANFLASYVVVTSLIAAAGGMMGFMLVERVFSGKPTFFGSATGTIAGLVAITPAADAVSPLGAFAVGALGAVVSFWAISWKKGHRVDDSFDVFAVHGMAGIAGALFVMLFGDPLAPAGVSGVFFGGELSLLWREPLAIIVTLTYAFGVTWLIATILNKFMTLRITSEAEYEGIDRAEHAESAYHLNSNGIGMATRTNFGPEIPEETVPDAVQVGVDKQKIADTRKASK
What is the function of this protein?
Involved in the uptake of ammonium/ammonia (NH(4)(+)/NH(3)).
What are the official names of this protein?
Ammonium transporter, Ammonia channel, Ammonium channel.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.