PharMolix/UniProtQA huggingface dataset:
Protein: ANMK_SALAR
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPGHLKKGILDICQGQLLTLSQLGQLDTQLGRLFAQAVNALLAQQHLQPRDIVAIGCHGQTVWHEPTGDAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPRQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGKVILPLLQKMLSDPYFAASAPKSTGREYFNYGWLERHLAAFPGASACDVQATLAELTAVSISHQVLLNGGCERLMVCGGGSRNPLVMARLAALLPGIEVATTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASKASILGAIYPATPELRVN
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: OBG_CAMC5
Sequence: MFIDSVNLTLSSGHGGAGAVSFRREKHVILGGPDGGDGGDGGDVYLIADNNSHTLAAYKGKRALKAQNGEAGSGRRMTGKKGENLELIVPPGTAVYDAQTNELLADLTKESERVLFLKGGKGGLGNVHFKSSINQAPEYAQKGLPEETRDVRLELKLIADVGLVGFPNVGKSTLISTVSNAKPQIANYEFTTLTPKLGLVEVDEYSGFVMADIPGIIEGASDGRGLGLKFLKHIERTKILLYMLDLANHRSLKEQFVTLRGEVEKFSPELAKRDFAIALTRMDAAENLERKVGEFLQILGLSGERSNLIDEAGKAGKNLIYKQDIYEFDDSKPYFVMPISSATNQNITELKFSLLELLKKGKFQMIFAGNLTETRG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_DELAS
Sequence: MSMLSFLLGEKKKTASVAKERLQIILARERVGGNGGGPDYLPALQKELMAVISKYVDIDVNDIKVHLERQENLEVLEVKIELPDASR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PYRD_XANOM
Sequence: MYSLARPLLFSLDAERAHALALRSIDTAYRTGTTSLLSTRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALLALGFGFVEIGTVTPRAQDGNPKPRMFRLPEYQAVINRMGFNNLGVDALVANVQRARRRGGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQSLRRLISDLRETQEALGAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRPLIANHPLAAEAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGINSGADAVAKMAAGASLVQCYSGLVYRGPQLVGECVNAIRRRREAPSGGAVAPL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RR11_HORVU
Sequence: MAKAIPKIGSRKKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GRPE_ACHLA
Sequence: MADKEKDAVIVDETEHVDVDSKESKKEKKTKQQQKIEFLEAEVKELNDKYLRTLAEAENFKKRIQAEKIMDRKYAASSFATELLVPYEQFSKIVDFPSDNELLNNFLIGFKMIRDQFKSVLENEGVVEIKALGEVFDAKVHHAIEKESNKDKPNGTVLEVLQNGYLFKDRILRPAMVKINEWSEDNGEDK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_COFAR
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKIK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYQ_ECOSE
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_RHOP5
Sequence: MTAPHTSANDRVIIFDTTLRDGEQCPGATMTFEEKLEVASLLDSMGVDVIEAGFPIASDGDFEAVHEIAKRAKNAVICGLSRAGAKDIDRCAEAIKPAKQGRIHTFLSTSPVHMKYKLQMDAAQVYELVISSVTRARNHTDNVEWSSEDGTRTEFDFLCKCVEAAIKAGASTINIPDTVGYSVPEEYYDLFKRVRENVPNSDKAIFSVHCHDDLGMAVANSLAGIRGGARQIECTVNGIGERAGNTALEEVVMAMKVRNDKLPYWNKIDTTMLTRASKVVSAATSFPVQYNKAIVGRNAFAHESGIHQDGMLKNAETYEIMLPESVGVKQTSLVMGKHSGRHAFIHKLEEMGYKLGQNQLEDAFVRFKALADRKKDIYDEDIEALVDLEIAQSHDRIKLVSLTVIAGTHGPQRATMKLDVDGQTKIEEAEGNGPVDAVFNCIKALVPHVAKLELYQVHAVTEGTDAQAEVSVRLSHEGRSVTSRASDPDTLVASAKAYLGALNKIVMKRQRDMAAPAAAAS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: HPRK_ALKCK
Sequence: MAKVTANDLLEKFQFELLAGEEGIYRPITTSDISRPGIEMAGFFTYYPARRLQLIGRTELSFLKSLSDQEKEERMTKLCTYDTPGIILSRGLEAPEQLIAAADKRGVPVLRSTLTTTQLSSRVTNFLESELAPVTAVHGVLVDIYGIGVLITGGSGVGKSETALDLVRRGHRLVADDSVEIRQQNEDTLVGYPPPLLQHLLEIRGLGIINVMTLFGAGAVRPFKRISLCMNLELWDQTKAYDRLGLEEDKMKIFDTEITKMTVPVRPGRNLAVIIEVAAMNFRLKRLGFNAAQEFSERLTQVIEHGENEF
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue.  Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CARB_STRZJ
Sequence: MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RR7_STAPU
Sequence: MSRRSTNEGRLTRPNPVYRNRLVNMLVNIILKNGKKSVAYRILHEAMKTIQQKTKKNPLAVVRQAIRRVTPNVAVKARRRGGSTYQVPVEIKPDQGKALAVRWILAAARKRPGRSMAFKLSYELMDAARQTGNAIRKREETHRMAEANKAFAHYR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPMI_CHLAA
Sequence: MTRPRPVVLIIMDGWGIAPPGPGNAADLADTPHVDAWMANCPFTTLGASGLDVGLPEGQIGNSEVGHLNIGAGFVVYQELTRISKAIADGDFFTNPVLLQAIEHVKQRNSALHLMGLFGPGGVHAHEDHLHALLELAHRHHLQRVYLHLFLDGRDVLPRSALGFLDTLEGVIARLGVGTIATVSGRYYAMDRDKRWERTGRAYAALVDGVGEKAPSARAAIEASYARDVSDEFVLPTVIVTASGEPTATVRDGDAVIFTNFRPDRGRQLTRAFVDPDLNERIRQHYERQKAEGQPLPATIWQRERQLRDLCFVTMTQYEEGLPVLVAFPPRYVTNPLAAVISQAGLRQFHIAETEKYPHVTFFLNGGREEPFPGEDRQLIPSPKVATYDLKPEMSAPEVTEALLAAIDSDQYDFIVVNYANPDMVGHTGSIPAVIKACEAVDAGLARVVPAILERGGVALVIADHGNAEQMIDPETGGPHTAHTTNPAPCFLIGGAGYGKDAIELRHGGRLADVAPTLLELLELEPSPDMTGQSLIVRRA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: THIK_ECODH
Sequence: MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: PDXB_PSEPK
Sequence: MLIVADENIPLLDAFFQGFGEIRRYPGRSLDAASVKDADILLVRSVTKVDRQLLEGSRVRFVGTCTIGTDHLDLDYFAEAGIHWSSAPGCNARGVVDYVLGSLLTLAELDGVALPERVYGVVGAGEVGGRLVRVLHGLGWKVLVCDPLRQAAEGGDYVSLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRELLLDREDVHAVLDVWEGEPQVDLQLADLCTLATPHIAGYSLDGRQRGTARIYQALCRFLGVNEQVRLAELLPKPPLAQIELDASTDLSWALATLCRAVYDPRRDDADFRRSLSDDPQQQRAAFDQLRKQYPPRREIEGLAVRLHGEAPQLAQLVSALGGVLV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET1_PICST
Sequence: MGILAALDLHPYTLVVSSFTVLLIQQLVGFIGKSTIQEFAWLFYLRVGGKLGLSNSFVAHTKKQEELHKLNREKRSISAQDEYAKWTKLNRQAEKLTAEVKSLSDDIAKDKSKINSLVGVVLLFLTTLPLWVFRLWFRKSVLFYLPTGVFPYYVERVLAIPFFASGSVGLTVWMFAVNNVISSVLFLLTFPFKPSVPIPIRQTKVEEVVPESAESKESSPEVIDIADAN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CPP1_ARATH
Sequence: MSSSLLLSGSTVSSSFIAPSKPSLVRNSSKTSLLPFRNVSRSFKTVKCTVDSSYGGNVPTFPRTRVWDPYKRLGVSPYASEEEIWASRNFLLQQYAGHERSEESIEGAFEKLLMSSFIRRKKTKINLKSKLKKKVEESPPWLKALLDFVEMPPMDTIFRRLFLFAFMGGWSIMNSAEGGPAFQVAVSLAACVYFLNEKTKSLGRACLIGIGALVAGWFCGSLIIPMIPTFLIQPTWTLELLTSLVAYVFLFLSCTFLK
What is the function of this protein?
Essential protein required during embryogenesis (PubMed:24097264).  Exhibits holdase chaperone activity involved in the stabilization of NADPH:protochlorophyllide oxidoreductase (POR) proteins against photooxidative stress during POR proteins import into chloroplasts.  Required for chloroplast biogenesis and development (PubMed:24151298, PubMed:25901327).  When expressed in yeast, triggers mitochondria-mediated cell death associated with the loss of mitochondrial membrane potential (PubMed:16192270).
What are the official names of this protein?
Protein CHAPERONE-LIKE PROTEIN OF POR1, chloroplastic, AtCPP1, Protein CELL GROWTH DEFECT FACTOR 1, AtCDF1.
What is the protein family that this protein belongs to?
Belongs to the chaperone-like protein of POR1 protein family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Plastid, chloroplast envelope. Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=Targeted to mitochondrion when expressed in yeast.
Protein: PPK1_SCHPO
Sequence: MNAQPFHNNTSDVQSFQDIISNSYQKPLSLVDSTDRALPDSSLSSLSRSTFQFHKHHLSGNENPQPSSESPYFTNNERLNSSSFPQIHDNQLSPSFNTSYQAIPSSSSNRSRGGPYTPSIRDDSLLALLSFSSNHRLHSMPSQLQPFNNASSYTTPMAPFTASFSNKVSHSAYPTRRLPSQAKKTSAIERVPVNLNFLQSDNLVVQSSPQTNFENFEFPKKIPSKEDLETREVLLLPPQTSKLSNKNLDTKSFTDVNKISQQGFVEISSNSSKVTPNTSLHQSFGIASSSSNNYMQTSSELTSSTEKMNGSHPLQLSNKSLLSIHLMQSKNQGHVSMTGSDKLSSHVQSETENAPVSKPSKPNTLTEDEKPLQSTKLPGNSLTVGELYQEPKSIQLPELSVSRTTYSAQSSSVKNCNERIPSAKALKKQKHLVPENKSKLQYVWQKKESLPYANLTSASNTHFFLSENQNDTSERLTRTLRKSTKNYTFGSYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLYRYICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLRSHVSLFETYNDDEATSLRPSPIRLLSQKSLASVSSVSSISTYSSSIELTPQITKTSLNREKPALHGSINLKHSTRPVVPIADGIYASTTLHPIDNAKNRLVSLLRRPKHKVKHAKVETRESPMKNKPTKKQHKRAFSMFERPTSQKAPLSPVESKINLMVAPKRVLNCASDSLRALLAGKTDKSFWGSRIPFLFNKLKSKQKAVSSSFNTENSFLILQAVSPLTFGGCFKEENAYGQKKQHMRHATVF
What are the official names of this protein?
Serine/threonine-protein kinase ppk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: Y5254_DICDI
Sequence: MIFKINKIKNVHMYDVAIILILIIVVFKLIKSEDSKFLNNNVQFEQTKDNKFGVNSTKLNFLFNFLSSSSNKSVFEIQKKNINNNYNNNNYNNNSKKSYNYIIVGELNRNKIIRPSDIQREISEINTVEKTVDIKEKRLGSFKRGVLKIPLAFVQMIAISIALICLLIP
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0280915.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MK13_BOVIN
Sequence: MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLIVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.  Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.  MAPK13 is one of the less studied p38 MAPK isoforms.  Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets.  Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.  Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1.  Mediates UV irradiation induced up-regulation of the gene expression of CXCL14.  Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development.  Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway.  MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 13, MAP kinase 13, MAPK 13.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: MNME_VESOH
Sequence: MNSSKTTICALASSVGKGGIGIVRVSGPLCKVIAKKMLGFIPKPRYAYYGLFFDQESTEIDKGIALFFPKPYSFTGEDVLEFQGHGGMIGMRLLLESAISMGAKLAESGEFSKRSFLNGKMDLVQAEAISDMINANSKRASKSAFRSLSGDFSNQINGLTKSIIELRVFVEATIDFSDEEIDFLQFDQVKCKIKDIKQTIETILKSATQGIILREGLNVAIAGKPNAGKSSLLNALTQESSAIVTDIAGTTRDVLKETIHVNGVPLSIIDTAGLRNSHDKIEKEGIKRANFEIEHADVVLMVFDAQDDKPDLSILPKNINDQSLLLIKNKVDLTSGAIKREVINDIVQLSVSAKYSEGIKLLRKELSNISGLEDLSEGVVLARRRHIIALEASLVSIGNAIMQLEIGAIELMAEDLRFAGQFMGSITGEFSSDDLLDEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_ALKEH
Sequence: MQAYLDLMAHVRHHGTPKSDRTGTGTLSVFGHQMRFDLSRGFPVVTTKKLHLRSIIHELLWFLSGDSNIAYLKANGVSIWDEWADENGDLGPIYGVQWRSWPTPDGRRVDQLAQVLRDLREHPDSRRHLVSAWNVGELPNMALPPCHTLFQFYVAEGRLSCQLYQRSADIFLGLPFNIASYALLTHMVAQVCDLKPGEFIWTGGDCHLYTNHLEQADRQLQREPLPLPRLRLNPEVRDLFAFRYEDIALEGYQHHPPIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_FRATW
Sequence: MYISNLRLQNFRNIPAKSFDFKNSINFIVGKNGSGKTSILESIYFLSHSRSFRSSQLNRIINHNADEFIIYTKAYNPDEITISLSRKKNSNNISKLNLEIQKNHTEITRNLPIQLINPESFNIINSGAQQRCKVLDWGAFYLDKTFLKIWQQTKFLVKQRNSALKQNYPYSYILSIDKKLCEFAEILDYKRQAYFTKLKPKIYEILSHFNPNLQLDIDYFRGWNLHKSLAQVLEESFNYDNKYKVTNHGPHKADIVLSVSHKPIQDIFSRGQQKLLICALKLAQGEIHNSENDNKCIYLIDDITSELDSIHTLTLFNYLKQLKSQVFITTTEKNKINEFIDTNSYILEI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.