PharMolix/UniProtQA huggingface dataset:
Protein: BRF2_MOUSE
Sequence: MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNFREVTYSRSTGENEQVSRCQQRDLRRVRDLCRILKLPLTFEDTAISYYQKAYQLSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGTICTLLYADLDLFSGTYMQMVKLLGLDVPSLCLADLVKSYCSSFKLFQASPSVPAKYVEDKDKMLSRTLLLVELADETWLVTGRHPLPIITAATFLAWQSLRPSDRLTCSLAQFCKLANVDLPYPAASRLQELLAVLLQMAGQLAWLQVLKLNKRSVVKHIGDLLQHRHMLVRTAFRDGTAEVETQQQQQQQQGQGQGQQDEVGDGPFDLPKRKRRASPTPLLPPCMLKPPKRTHTLPPESAVTGDEDISDSEIEQYLRTPQEVRDFERAQAASQAAMRVPNPP
What is the function of this protein?
General activator of RNA polymerase III transcription.  Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.  Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress.  Down-regulates expression of target genes in response to oxidative stress.  Overexpression protects cells against apoptosis in response to oxidative stress.
What are the official names of this protein?
Transcription factor IIIB 50 kDa subunit, B-related factor 2, BRF-2.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_OREOR
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFIETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGISSDTDKIPFHPYYTIKDILGALLLILALLLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILTPMLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYC_CLOPS
Sequence: MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFKVDFVQNFTDIDDKMIKKANEEGITVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGEIIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIEDLQSGARISVDERKKDPMDFAIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQSEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQLNFSEDLLESAKASVERIYNAIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMDDDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIRELGAPLGMFQKSTKGNLEEEIEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKRI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JHD2C_MOUSE
Sequence: MQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHGHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEDKYDCVSRGENPKGKNKHVVTKRRKPEEAEKRLSMKRLRTDNASDASESSDAESSSKRVTETSSSEPMPEYEPKNKVTSKVNGEEGQSQAAEEAGEETLIDTRPPWDQMQEDKNHNEGEKPKSTDSHLQDKMTLRSSEQATVADHNSNDSVLQECNVENQRTVELLPKDRLVSRTPTPKCVTDIKNDTHSERAAQENLNTFGLQTPENMDPNVSDSKHSNAKYLETAKQDCDQSWVSDVVKVDLTQSSVTNAPSGSDKRDTEKERNHYVSYMSSLSAVSVTEDQLHKRSPPPETIKAKLTTSVDTQKAKSSSSPEVVKPKITHSPDSVKSKAAYGNSQAVGERRLANKIEHELSRGSFHPVPTRGSALETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFSLHSSSHRTCLNPGTHHPALTPGPHLLAGSTSQTPLPTINTHPLTSGPHHPVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPHKITVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCHLHRHFVGPRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKQDKDVDRSVSEIYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYTEKQNNNLSATANPQTHSFISSLSKPPPLIKHQPESESLVGKIPDHLPHQSASHSVTTFRSDCRSPTHLTVSSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQSNFKNSSDQSLTEMWRSNNNLNREKAEWPVEKSSGKSQAAVASVIVRPPSSTKVDSVPSVPLASKDRVCERSSSGANKTDYLKPEAGETGRIILPNVNLESAHVKSEKNFEAVSQGNVPVSVMSAVNVVSTTKADVFTSAATTTSVSSLSSAETSYSLSNTISASTPFECTSSKSVVSQAVAQAKDCTVSTAVPGTLACSKTGSAVQPGSGFSGTTDFIHLKKHKAALAAAQFKNSSVSEAELNTVRNQTVAASLPLDSTMTCTASNKAISVGNGPAAQSSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSNDIENRADGRVAVDKYGRDEKVSRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEVEEDSKPNGVLSRSAKDKSKLKLQNSNSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENYEDDEVDVETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMLTQIIPGSVLTDLLDAMHILREKYGIKSHCHCTNRQNLQGGNVPTMNGVSQVLQNVLHHSNKTSVSLPESQQQNSPQKSQTNGNSSPGSASTDSRLTPPESQSPLHWLADLAEQKSREEKQENKEFTLEREIKEDGDQDASDSPNGSTSPPASQSNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGTSSGKGGRTMPNILDDIIASVVENKIPPNKTSKINIKSEPNEEPKESSLPATDESNKSYRDIPHSWICDQHILWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKAMMPTRYEDFLRCLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAKGNGVLSKAGILKKFEEEELDDVLRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNRKLRQRLLEEYGVRACTLIQFLGDAIVLPAGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELRLLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT
What is the function of this protein?
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.  Demethylation of Lys residue generates formaldehyde and succinate.  May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
What are the official names of this protein?
Probable JmjC domain-containing histone demethylation protein 2C, Jumonji domain-containing protein 1C.
What is the protein family that this protein belongs to?
Belongs to the JHDM2 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: JUPI1_HUMAN
Sequence: MTTTTTFKGVDPNSRNSSRVLRPPGGGSNFSLGFDEPTEQPVRKNKMASNIFGTPEENQASWAKSAGAKSSGGREDLESSGLQRRNSSEASSGDFLDLKGEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSRRNPPGGKSSLVLG
What is the function of this protein?
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408).  Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422).  Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365).  Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
What are the official names of this protein?
Jupiter microtubule associated homolog 1, Androgen-regulated protein 2, Hematological and neurological expressed 1 protein.
What is the protein family that this protein belongs to?
Belongs to the JUPITER family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GLGB_ECO57
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPLNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: GDA6_WHEAT
Sequence: MKTFLILALLAIVATTATTAVRVPVPQPQPQNPSQPQPQGQVPLVQQQQFPGQQQQFPPQQPYPQPQPFPSQQPYLQLQPFPQPQPFPPQLPYPQPPPFSPQQPYPQPQPQYPQPQQPISQQQAQQQQQQQQQQQQQQQQQQILQQILQQQLIPCRDVVLQQHNIAHARSQVLQQSTYQPLQQLCCQQLWQIPEQSRCQAIHNVVHAIILHQQQRQQQPSSQVSLQQPQQQYPSGQGFFQPSQQNPQAQGSVQPQQLPQFEEIRNLALQTLPRMCNVYIPPYCSTTIAPFGIFGTN
What is the function of this protein?
Gliadin is the major seed storage protein in wheat.
What are the official names of this protein?
Alpha/beta-gliadin clone PW1215, Prolamin.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: RS6_ICTPU
Sequence: MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADPLGDEWKGYVVRISGGNDKQGFPMKQGVLTNGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIIRKGEKDIPGLTDSTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRRPLTKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKRQRTQKNKDEAAEYAKLLAKRLKEAKEKRQEKIAKRRRLSSLRASQSKSESSQK
What is the function of this protein?
Component of the 40S small ribosomal subunit (By similarity).  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity).
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: MMPOS_HUMAN
Sequence: MGAQLSGGRGAPEPAQTQPQPQPQPAAPEGPEQPRHPPQPQPQPQPQPQPEPSPWGPLDDVRFLIACTSWY
What are the official names of this protein?
Protein MMP24OS, MMP24 opposite strand.
Protein: PDXA_RHILO
Sequence: MKSAMTALALSVGDPSGIGPEIAIAAFLAREAVGLPAFYLLADPALIASRASRLGVSVPIVETTPALAAQVFARALPIVPLAARFIDSPGRPDPANAAGTVEAIDRAVAACLAGDAAAMVTCPIAKKPLYDAGFRFPGHTEYLAHLAARHSGVEAMPVMMLAGPDLRTVPVTIHIALAEVPKALTTELIVATARITAADLAGRFGIARPRLAIAGLNPHAGEGGSLGLEDEHIVRPAVDILRAEGIDAFGPLAADTLFHARARAGYDAALCMYHDQALIPAKTLAFDDAVNVTLGLPFIRTSPDHGTAFDIAGKGIARPDSLIAALKLARTLADTDKKAAAA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOS_ATHNI
Sequence: LLHLLGSGGFGSVYKAIYHGATVAVKKVKRCSKNHLASRQSFWAELNVARLDHNNVVRIVAASTCTPASQDSLGTIIMEYAGNCTLHHVIYGTGYLTGNNSDSLKCDHGFLSTAQAVIYSHDIVAGLMFLHSQLIVHLDLKPANIFITEHNVCKIGDFGCSQKLEDSESSGLYICHQGGTYTHRAPELL
What are the official names of this protein?
Serine/threonine-protein kinase mos, Oocyte maturation factor mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: VESP_CROAD
Sequence: MSPSAGLQFSLYFLQTKKVLWKLTDKEKGLCYILLFTLCFFADQENGGKALASPPGIWKRADVTFDSNTAFSSLVVSANKKTVKNVGVPQVVPDNPERFNSSPCVLGSPGFRSGKHYFEVKYGTQREWAVGIAGKSVKRKGNLMLVPEERIWQMGLWWLRHLETDPGRVHSTSGKITVFVDYNGGNVIFDLNRINTTLKANFNGEEVVPFFYLGGTVSLTTL
What is the function of this protein?
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice.  May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
What are the official names of this protein?
Vespryn.
What is the protein family that this protein belongs to?
Belongs to the ohanin/vespryn family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMA_CAMHC
Sequence: MSCSYYGKCAGCNLNLPYNDEISFKTDFLKSEFKEFYQGEIEIFKSDEWNFRNHAEFGIWHEKGDVFYTMRGNSNERVKIETCPKMDKKIVEMMPKLLQNLRENKNLKERLFGIEFIATKFDFMAILLYHKDIFNIKDDLAKLAEILDIKISARSRGKFLNFGGEILREKVQNFIYRFNADAFFQSNTKVNEKMILFVLNAVKNGKDLLEMYCGHGNFTLPLASEFGKILANEISKNSIKNARENSKNKDNINFVRMSAKELIDAFNGVREFNRLKDIDITDFDFSHVLVDPPRAGIEPEVLDFIQNFKNIIYISCNPASLKQNLQILCETHKITKFALFDQFVHTEHIECGVVLQK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: DER_CHLMU
Sequence: MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQESTDRFQKQIHKQALAAAEEASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKADSQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQVAEIPLPSAEEQENTQEEEFSSKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKSSIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSSRTEKAISRADICLLVIDATQQLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQDLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIATTKLSTSLVNKVLAGAMQRHHPQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLEYKAKPARKSN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: LUXS_ECOLI
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NUOA1_PSEAB
Sequence: MPNPAELAAHHWGFAAFLLGVVGLLAFMLGVSSLLGSKAFGRSKNEPFESGIVPTGGARLRLSAKFYLVAMLFVIFDVEALFLFAWSVSVRESGWAGLIEATIFIAILLAGLVYLWRIGALDWAPESRRKRQAKLKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 1, NADH dehydrogenase I subunit A 1, NDH-1 subunit A 1, NUO1 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IPYR_THEKO
Sequence: MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPQTWYDDGDPFDIMVIMREPVYPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFQRYKELQGKTTTVEGWGNAEEAKKEILRAIELYKEKFGKKE
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_BACCN
Sequence: MIFVLDVGNTNAVLGVFEEGKLCQHWRMETDRHKTEDEYGMLIKQLLEHEGLSFGDIKGIIVSSVVPPIMFALERMCEKYFKIKPLVVGPGIKTGLNIKYENPREVGADRIVNAVAGIQLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITKPSSIVGKNTVSAMQAGILYGYVGQVEGIVKRMKEEAKQEPTVIATGGLAKLIAEESNVIDIVDPFLTLKGLYMLYERNAILQHEKGE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_PSEFS
Sequence: MLTWLQRDSLTFPPLAKAMREPNGLLAAGGDLSAERLIQAYRHGCFPWFSQGQPILWWSPDPRTVIFPDELHISRSLGKLLRQQRYTVTFDQDFAAVIQACAAPRAYADGTWITQSIQNAYLALHQRGYAHSVEVWDNGELVGGLYGLAMGQLFFGESMFSRADNASKFGFATLTRQLQAWGFVLIDCQMPNDHLHSLGARAISRSDFAGFLRDHLDQPNTGPWVS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCAS1_CANLF
Sequence: MAITQFRLFKVCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNALEQLEPDYFKDMTPTIRKTQKIIIKKREPLNFGIPDGSTGFSSRLAATQDMPFIHQSPELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKIADREKRAAEQQRKRMEKEAQRLMRKEQNKIGVKLS
What is the function of this protein?
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
What are the official names of this protein?
Receptor-binding cancer antigen expressed on SiSo cells, Cancer-associated surface antigen RCAS1, Estrogen receptor-binding fragment-associated gene 9 protein.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type III membrane protein. Note=Predominantly located in the Golgi.
Protein: RSMH_EXIS2
Sequence: MFEHETVLKWESIKGLNIKPDGIYVDCTLGGAGHSEEIVKQLTTGHLYAFDQDDVALAHAAERLAAYEGRFTLIKSNFVHLKEELEARSVTKVDGILFDLGVSSPQLDEGERGFSYNFDARLDMRMDQTSPLSAYEVVNEWPYNDLVRILFTYGEEKFSKQIARKIEKAREIAPIETTFELVELIKDAIPAPARRKGGHPAKRTFQAIRIAVNDELNVFDRAVYQAIDLLAVGGRLCVITFHSLEDRMCKQAFKEKSSLPELPQGLPMIPKEFEPELRLVTRKPITAGDDELDDNRRSRSAKLRIVEKMKES
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDX3_PONAB
Sequence: MAAAVGRLLRASVARGVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSYHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPNPAASKEYFQKVNQ
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.  Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (By similarity).  Required for the maintenance of physical strength (By similarity).
What are the official names of this protein?
Thioredoxin-dependent peroxide reductase, mitochondrial, Peroxiredoxin-3, Thioredoxin-dependent peroxiredoxin 3.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Early endosome. Note=Localizes to early endosomes in a RPS6KC1-dependent manner.
Protein: HIS4_HALMA
Sequence: MYPEFEVVPAVDMQDGQVVQLVGGERGTEKTYGDPVEAAQRWVDAGARTLHLVDLDGAFEGERQNAAAIDAVLDAVGADVDVQLGGGIRTAEDAVSLLDRGLDRVILGTAAVETPEIVGEISDEHPGSVLVSLDAKDGEVVVSGWTEGTGLDPADAAGRYADLGAGGILFTDVDVEGQLDGVRTDPVRRLVDSVDIPVIASGGVATINDVLALRSAGAAAVVVGSALYEGQFTLDAAIDALGESSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPXN1_GORGO
Sequence: MEKPTSSTNGEKRKSPCDSNNKNDEMQETPNRDLVLEPSLKKMKTSEYSTVLVLCYRKTKKIHSNQLENDQS
What are the official names of this protein?
Sperm protein associated with the nucleus on the X chromosome N1, Nuclear-associated protein SPAN-Xn1, SPANX-N1, SPANX family member N1.
What is the protein family that this protein belongs to?
Belongs to the SPAN-X family.
Protein: MURA_SHEPA
Sequence: MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFMDMISVGATENLLMAASLADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSFLVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIERLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERVKS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM6_YEAS7
Sequence: MLGLKGCLTILIGYVIAVCALFSSRGRNPSLTDWEKLKDQKISNIDNFGLTGQHLLEFFQENLPFLSFSEEKYRHKHVSLYYDVFKEYILRRASSKKCLPVDSAIAKLNKDVNPMPVHSHNDYWRKLPLFEGLAYGASSTEADVWNIDEKILAVGHNEAYLDPVELTLDKLYTGPLLEILDEVNCQDSDSDRKNGVFFNSPETSLFFYIDFKSDDNELTYKLLMEQYFKSLIDSGYLTYYDMKKDEIIWRPVTVILTGNYPTSLDILDNGNDNGYFESNQRFAFLDAPLLSLEPKYSKLSVAATVSFSQLMKHCGSDHWKVSLRGRMDSNEISCAKSIIDGAHALKLKTRIWGAPTWPANLVETISRQIIHDLGSDLLNLDNLFMASSLI
What are the official names of this protein?
Altered inheritance of mitochondria protein 6.
What is the protein family that this protein belongs to?
Belongs to the AIM6 family.