PharMolix/UniProtQA huggingface dataset:
Protein: MTRA_METV3
Sequence: MADKKAPATGWPVANGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIEKVIVNYISNPNIRFMVVTGSEVQGHITGQCFKALYENGIGDDGGIIGAKGAIPFMENVGQEPVARFQNQIVELIDMIDSEDKGKIQQTVKDCISKDPGAFEEDAMVIDLEGKAGGAGEEEGSSVKITSPEMAIIESRMRIISKQIEQAAIVNKYNSGYYNGKIQGVAIGLFLSLLIYSMLLI
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: S35A4_HUMAN
Sequence: MSVEDGGMPGLGRPRQARWTLMLLLSTAMYGAHAPLLALCHVDGRVPFRPSSAVLLTELTKLLLCAFSLLVGWQAWPQGPPPWRQAAPFALSALLYGANNNLVIYLQRYMDPSTYQVLSNLKIGSTAVLYCLCLRHRLSVRQGLALLLLMAAGACYAAGGLQVPGNTLPSPPPAAAASPMPLHITPLGLLLLILYCLISGLSSVYTELLMKRQRLPLALQNLFLYTFGVLLNLGLHAGGGSGPGLLEGFSGWAALVVLSQALNGLLMSAVMKHGSSITRLFVVSCSLVVNAVLSAVLLRLQLTAAFFLATLLIGLAMRLYYGSR
What is the function of this protein?
Mediates the transport of CDP-ribitol (PubMed:34015330).  Does not exhibit CMP-sialic acid, UDP-galactose and UDP-N-acetylglucosamine transport activity (PubMed:28167211, PubMed:34015330).
What are the official names of this protein?
Probable UDP-sugar transporter protein SLC35A4, Solute carrier family 35 member A4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: XERDL_STRT1
Sequence: MTISSFQKQLTTQITNFLARKTISDSSKQAYAYDLKQFVNCLPGRVDQTSLKLYENQLKEWKPSVQKRKRSAVNQFLLYLYQKGELEEFFKLSETAPLPSQQEELEIFDLSSLYEGQEGPGKLACLFILELGLLPSEILELKWEDIDLDFGVVTVAKGSTKRVLRLDGALKELLFGIKNDNSQGLILSKAFTRQWLYKQIQSYVGGCGLSGVTAQALRQQYILRQIEKGTGAFELARLLGLKSPVTLEKYYKT
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_ECOHS
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: XYLA_ECO8A
Sequence: MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHX1_HUMAN
Sequence: MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW
What is the function of this protein?
Potential transcription factor.  May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.
What are the official names of this protein?
LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, hLim-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS7_RHOOB
Sequence: MTDRIARVERTTKESSITVELNLDGTGIVDVSTGVPFFDHMLTALGSHASFDLTVHAKGDIEIEAHHTVEDTSIVLGQALGQALGDKKGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTGEPEHLLHAVIGGYPGVPYATVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVARALREAVEPDPRVTGVPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SHEON
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRSSVAAYGYSEIRTPIVENTDLFKRSIGEVTDIVEKEMYTFEDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEIYGIGSADIDAEVLMLSARLWEKLGITEHVTLELNTLGDPAERAAYREALIAFLEQHKDKLDEDSQRRMYSNPLRVLDSKDPQVQSILADAPALMDYLGEESSQHFAQLRELLDAVGIQYRVNSRLVRGLDYYNRTVFEWVTNSLGSQGTVLAGGRYDGLVAQLGGKETPAVGFAMGLERIVLLLETLALTQDIPAEVDVYVAAMGDNCLVEAIKVAQELRSALPTLRVMSHCGGGNLKKQMKRADKSGAQVALLIGEEELAEGVVTVKYLRNDNEQQRVARNALSAFLAELTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_ECTSI
Sequence: MVATLERREEKRDWGTFATWITSTENRLYIGWFGCLMIPTLLTAASCYIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVIPSSNAIGIHFYPIWEAASIEEWLYNGGPYQLIVFHFLIGVACWMGREWELSYRLGMRPWIFVAFSAPVAAASAVFLVYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMRPFHMAGVAGVFGGSLFSAMHGSLVTSSLIRETSEVESVNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRALHFFLAAWPVVGIWLTALGVSTMAFNLNGFNFNQSVVDSEGRVINTWADIINRADLGMEVMHERNAHNFPLDLASNEILPVAISAPSVVG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL7_NEUCR
Sequence: MSTSVPTKNDVLVPETLLKKRKSQEKARAERQAEIEKKKAANKEKRAVIFKRAETYVKEYRDVEREKIRLQRAAKQDGSFHIPAEAKLIFLIRIKGINKIPPKPRKILQLLRLLQINNGVFVRVTKATAEMIKIVEPWVAYGYPNLKSVKELIYKRGYGKVNKQRVALTDNSIIEENLGKYGIICMEDLIHEIYTVGPNFKQASNFLWPFKLSNPTGGFRTRKFKHFIEGGDLGNREEHINALIRQMN
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PDXA_XANAC
Sequence: MMVPSLALVPGEPAGIGPELCVRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLEPDQPARAPGDLPLHPIRQAVATRFGAPDPANAAAVIAGLRSAAADCLAGRLQGIVTGPVHKAAINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTTHLPLRAVADAITADALLQCLRITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPALEQLRGEGMQLIGPLPADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAGRGIADPSSLMAATALCARLAARR
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CLOBK
Sequence: MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAGAGAAEEKTEFDVVLADAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TPMT_MARN8
Sequence: MEHEFWHERWAKDQIGFHEGTVNQYLHDHWPELAGNGTDAVFVPLCGKAHDMWWLHDRGHPIIGVELSEVACKDFFEEAQEKASVHPGEPFTTFRHDDLQIWCGDYFQLVPDDLKHIRLVYDRAALIALPPEMRKSYVNHLTAIIPDDTRILLITLDYDSSEMQGPPFNVTDDEVFRLYGEDYEINQVLKRDMARDNPFAKRRGLRNGATESVFTLVKK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RERE_MOUSE
Sequence: MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDNNSATTEESNKKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHSSQACCRSPAPAFCDPPACSLPVAPQPPQHLSEAGRGPGGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPSKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGLHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL
What is the function of this protein?
Plays a role as a transcriptional repressor during development.  May play a role in the control of cell survival.
What are the official names of this protein?
Arginine-glutamic acid dipeptide repeats protein, Atrophin-2.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs (By similarity).
Protein: RL5_PROM1
Sequence: MSLKTRYRETIRPKLLKDLGLKNVHQVPKVQKVTLNRGLGEAATNSKALEASLKEMATISGQKALVTRAKKAIATFKIRQGMPIGCSVTLRGDRMYAFLERFINLALPRIRDFRGVSPKSFDGRGNYTIGVKEQLIFPEITFDKVDTIRGMDITIVTSASSDEQGKALLSEMGMPFRKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CYB_BOSTR
Sequence: MTNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFASVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMIHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILALMMLVLFAPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVMALVLSILILILMPLLHTSKQRSMMFRPLSQCMFWILVANLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPTASMIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TUSA_BUCAI
Sequence: MKKNIILNLIGLRCPEPIMIIRKTIRDMKDNEKILILSDDPATKRDIPNFCYFMEHKLLKNEIKVKPYRYLLKKGL
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOT10_ARATH
Sequence: MDEKDRPKNLREEEEKPSEETKILISSLPWEIDYLGNKLFNYEGYWYSEDILQSIPNIHTGFQPQETDIILASFYKSGTTWLKALTFALVQRSKHSLEDHQHPLLHHNPHEIVPNLELDLYLKSSKPDLTKFLSSSSSSPRLFSTHMSLDPLQVPLKENLCKIVYVCRNVKDVMVSVWYFRQSKKITRAEDYSLEAIFESFCNGVTLHGPFWDHALSYWRGSLEDPKHFLFMRYEDLKAEPRTQVKRLAEFLDCPFTKEEEDSGSVDKILELCSLSNLRSVEINKTRTSSRVDFKSYFRKGQVGDWKSYMTPEMVDKIDMIIEEKLKGSGLKF
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to specifically catalyze the sulfate conjugation of brassinosteroids, including castasterone (CS), brassinolide (BL), related 24-epimers, and the naturally occurring (22R, 23R)-28-homobrassinosteroids.  No activity on phenolic acids, desulfo-glucosinolates, flavonoids, steroids, gibberellic acids, cytokinins, phenylpropanoids, hydroxyjasmonates and coumarins.
What are the official names of this protein?
Cytosolic sulfotransferase 10, AtSOT10, Sulfotransferase 4a, AtST4a.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTBDG_RAT
Sequence: MKMLNSRKIRMERRIVGATNRWRFPQDHFCGDLLALSQMCNVLNVDLDDALKNPDKLCISKFQKLFTESIMDSGTQSGEADVILDCLGFKWELHHPQIFQSETLAKLYLTALIQNTKSSQRDLEKILKVHSTERMKKRSPVKKIIISLRINDPAVTRVAFALALKNLYMNEVEMTVDNVLGVLASAHILQFNRLFRKCVSTMLNRLTPCTIKNFYLAGCKYKEEQLTNACEKWLAMNLVPLVGTQIHLRHIPEPLLYKVLKSPRLFTFSEFHLLKTLLMWVYLQMNGKVQTLPIHETMLAFFSSFPKKSCFLEQDPGHSWMPLFLCLRLHGITSGKDLEEIKHINFFPESWLVRVTANHYHALESGGNMVHLKDLSTQAMRFGLLFRQEYTTYSETISIYGYFFEIKGIKHDTTSYSFSMQRIRHTDLECPSSVCEHSTISLRSERLVKYEIRAQTLVDGRWQEFGTNQIMQKFGFIKPGCKSHALKIQTVGIPIYASFAFIFPAS
What are the official names of this protein?
BTB/POZ domain-containing protein 16.
Protein: ATE1_SCHPO
Sequence: MVLDKLLYTGYNVSTECGYCKSGRKTEHFGLLAEKLSCEDYQRLIDLGWRRSGHYLYKPNGKTSCCSLYTIRLDSYNFKIAKEQKKAIKKWVKYVNGKPLKPMKSEISTDYLNNAFQTIESLGAEKYSVTMEPCTYTDEKFEVFKKYQMQVHLEKEEEITKKGFSRFLCNSPLFNEDKGIKYGSYHQMYRFQGRLVAVGVLDLLPHGVSSVYLFYDPDMSKFSLGRISACREIWLALECGYRYYYMGYYIHTCPKMKYKATYSPSYLLNPGTNKWIPIENFTSLWNTGAPKYISFGDENNSDIQTAVDYDSSEDSSQNEDDYTLFNRQLPGILSVNVAESLVSENFANIGNSTFPTRHVLSYFPQVKHWFVEINAAVGEEVAKSYTLVLSS
What is the function of this protein?
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein.  This arginylation is required for degradation of the protein via the ubiquitin pathway.  Does not arginylate cysteine residues (By similarity).
What are the official names of this protein?
Arginyl-tRNA--protein transferase 1, Arginyltransferase 1, R-transferase 1, Arginine-tRNA--protein transferase 1.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COAE_COXBU
Sequence: MLRIGLTGGIGSGKSTVANYFAELGAPVIDADQIAHEITKPDQAAFKQIINHFGNAVLTKGKFLNRTKLRELIFENPDDRQWLENLLHPLIIAKMKTQLKKIKAPYCILAIPLLAEASQSVDFIDRILVVDAPETLQIQRTKSRDQLSDQQIQLILQSQSPREKRLAIADDVIVNDQTIPILRKAVFQLHCKYLQIAQT
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORTL_BPPCD
Sequence: MELEKIRAIISADAARRQEILQAKSYYYNKNDILKKGVVVQNRDENPLRNADNRISHNFHEILVDEKASYMFTYPVLFDIDNNKELNEKVTDVLGNEFTRKAKNLAIEASNCGSAWLHYWIDEEYSGEQVTNQTFKYGVVNTEEIIPIYRNGIERELEAVIRYYIQLEDVKGQIQKQAYTYVEFWTDKILDKYKFFGVSCCGSQIEHITVQHRFNSVPFVEFSNNIKKQSDLSKYKKILDLYDRVMSGFANDLEDIQQIIYILENFGGEDTSEFLKELKRYKTIKTETDSEGDSGGLKTMQIEIPTEARKIILEILKKQIYESGQGLQQDTENFGNASGVALKFFYRKLELKSGLLETEFRTSFDKLIKAILYFLGVTDYKKIQQTYTRNMMSNDLEDADIATKSVGIIPTKIILRHHPWVDDVEEAEKLYLEEKKIQASKVSDDYNNFTE
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.
What are the official names of this protein?
Portal protein, Portal vertex protein.
What is the protein family that this protein belongs to?
Belongs to the SPP1-like portal protein family.
What are the subcellular locations of this protein?
Virion.
Protein: KR121_MOUSE
Sequence: MCHTSCSSGCQPSCCVSSSCQPSCCVSSPCQASCFVSSPCQPSCCVSSSCQSACCRPAICIPVRYQVACCVPVSCGPTVCMAPSCQSSVCVPVSCRPVCVTSSCQSSGCCQPSCPTLVCKPVTCSNPSCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).
What are the official names of this protein?
Keratin-associated protein 12-1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 12 family.
Protein: APAH_BUCAT
Sequence: MSTYFISDIHGCYEEFRILLEKSSFNDKKDYLWIAGDLVSRGPDSLEVVKYLYSLKDRVQIVLGNHDINLIAVHAGIKDNKKENYFDEFLSSPDSVELINWLRCQSFLKVDEKRKIIMSHAGISPQWDINIAKVCALEIEDRLSHKNYALFLKEIYHNNIDFWRLDLNQLDRLRYSMNSFTRMRYCYPDGRLNMFCKKSPDFVKYPLRPWFLMPSSISKVYSIFFGHWSSLKGTHVPKPFFPLDAGCCWGEELVMLRWEDGKWFSQAYLSKKCI
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: MIAA_ONYPE
Sequence: MKKVIAITGPTASGKTSLSIKIAKKFNLEIINCDSLQMYQKYDIGTAKITLEEAQGIKHHLLDFLAPGTNYSIYHFQKDARKKIEETPLPLFVGGSGLYLKSALFDYELTPKSLFLPPTSLPAIENMIDFIKQKDPQLIANLDLKNPRRILSAYQDLLEGTLRSQKNKKHNSLYSSLIFYLDIDRQILKKRVILRLEQMLKQGFIEEVNQIQTHFPNPNFNIIGYREIKALLEGKITLDQAKTLIIQKTMQYAKRQKTWFKNQIKPIILDALSPDLEKTTICLINDFLKTD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MAD2_ARATH
Sequence: MASKTAAAKDIITLHGSAAIVSEFFCYAANSILYNRAVYPEESFVKVKKYGLPMLLIEDESVKSFMSNLTSQISEWLEAGKLQRVVLVIMSKATGEVLERWNFRIETDNEVVDKGVSREKSDKEIMREIQAIMRQVASSVTYLPCLDETCVFDVLAYTDTDVAVPFTWIESDPKLIANPQMVKLHGFDTKIHKVDTLVSYKNDEWDEEE
What is the function of this protein?
Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete.  It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
What are the official names of this protein?
Mitotic spindle checkpoint protein MAD2, Mitotic arrest deficient protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAD2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Chromosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Cytoplasmic in interphase cells. Accumulates onto both kinetochores and the spindle microtubules in cell arrested in metaphase. Present in chromocenters. Associates with unattached kinetochores upon spindle assembly checkpoint (SAC) activation. The nucleus envelope association requires the presence of NUA.