PharMolix/UniProtQA huggingface dataset:
Protein: RL16_KLEP7
Sequence: MLQPKRTKFRKVHKGRNRGLAQGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFGLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DXS_NITMU
Sequence: MHPLLNTITDPVKLRALDRKLLPQLADELRQFLVESVAKTGGHLSSNLGTVELTIALHYVFNTPYDRLVWDVGHQTYVHKILTGRREGMSKLRMRGGIAGFPRRDESEYDAFGTAHSSTSISAALGMAVASQWEGKKRSVVAVIGDGAMSAGMAFEALNNAGAMDTNLLVILNDNDMSISRPVGALNNYLARLMSGQFYATARRAGEKMLGVVPHVLELAKRAEEHVKGMVTPSTLFEEFGFNYIGPIDGHDLDVLVSTLNNIRNLRGPQFLHVVTRKGAGYKAAEDDPILYHGVTRFNPDAGIIPKASVKPSYTQVFGDWLCDMAALDQRLVGITPAMREGSGMVRFSHEYADRYFDVGIAEQHAVTFAAGLACDGLKPVVAIYSTFLQRAYDQLIHDVAIQNLPVVFAIDRAGLVGADGPTHAGSFDLTYLRCIPNITVMAPSDENECRQMLYTAFQMNTPAAVRYPRGSGSGVAQQKEMQMLPLGRGEIRREGAEIALLAFGSMLQPCLEAAEELNATVANMRFVKPLDDDLVASLAANHELLVTVEENTVMGGAGSAVLESLSARGRTVPVLQLGLPDTFLDQGDPSQMLSECGLDREGIVHAIRARFPK
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LITAF_XENTR
Sequence: MQTSGNYQPVPIGFTVPSAPPSYEEATFHHPPYPPLHQGMDAKNMSNPPYIVQPVPMQPPVTVQTVYVQQAMTLYDRPVQMCCRSCNSMITTRLEYSSGALAWLSCGGLCLLGCIGGCCLIPFCIDSLKDVDHYCPNCHALLGSYKRI
What is the function of this protein?
Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation.  May also contribute to the regulation of gene expression in the nucleus.  Binds DNA (in vitro) and may play a synergistic role in the nucleus in regulating the expression of numerous cytokines.
What are the official names of this protein?
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog, LPS-induced TNF-alpha factor homolog.
What is the protein family that this protein belongs to?
Belongs to the CDIP1/LITAF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane. Late endosome membrane. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane. Note=Associated with membranes of lysosomes, early and late endosomes. Can translocate from the cytoplasm into the nucleus (By similarity). Detected at Schmidt-Lanterman incisures and in nodal regions of myelinating Schwann cells (By similarity).
Protein: TATB_STRGG
Sequence: MFNDIGALELLTLGVLAVLVFGPDKLPKLIQDVTRTIRKIREFSDSAKEDIRSELGPQFKDFEFEDLNPKTFVRKQLMDGNDDLGLKEIRESFDLRKEISDVTDAVNGRTPAASDTANSAVNGSAGAAADGVTTSLTKTGETTPDLLKKAPQQAQPERPPFDADAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HICA1_PHOLL
Sequence: MKQSEFRRWLEAQGVEVSNGTNHLKLRYQGKRSIMPRHPSQEIKEPLRKAIIKQLGL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  A probable translation-independent mRNA interferase (By similarity).
What are the official names of this protein?
Probable mRNA interferase HicA 1, Endoribonuclease HicA 1, Toxin HicA 1.
What is the protein family that this protein belongs to?
Belongs to the HicA mRNA interferase family.
Protein: HIS2_PSEPK
Sequence: MSDTLNRLAEVLEERKQAAPDSSYVASLYHKGLNKILEKLGEESVETIIAAKDAQISKDYSDVIYETADLWFHSLVMLSALGQHPQAVLDELERRFGLSGHDEKAARQPSA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXG_SALTI
Sequence: MLKTIRKHGITLALFAAGSTGLTAVINQMTKSTIHEQALQQQHALFDQVLPPDRYNNNLQESCYLVDAPALGKGTHRVFIARKDDKPVAAIIEATAPDGYSGAIQLIVGADFNGTILGTRVTEHHETPGLGDKIERRLSDWITHFSGKTISGENDTHWAVKKDGGDFDQFTGATITPRAVVNAVKRAGLYAESLPAQLPHLTACGE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rsx electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYB6_CITSI
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEVNFGWLIRSVHRWSASMMVLMTILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPEAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NNR_MYCTU
Sequence: MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: MURD_YERPE
Sequence: MVDYQGKKVVIIGLGLTGLSCVDFFIARGVTPRVMDTRINPPGLDQLPESVEQHVGDLNQEWLLDADLIVVSPGMALAHPALSEAAEAGVEIIGDIELFCRENQAPVVAITGSNGKSTVTTLVGEMAKAAGWSVGGGGNIGVPALTLLKQDNQLTVLELSSFQLETTHSLRASAATILNVTEDHTDRYPLGLQQYRAAKLRVYENAKVCVVNADDALTMPVRGADSRCISFGVDVGDYHLNKQQGEIWLRVRGEKVLNTREMKLSGRHNYTNALAALALADAVGIPRASSLKALTTFSGLPHRFQLVLERHGVRWINDSKATNVGSTEAALDGLQVDGTLHLLLGGDGKSADFSGLTHFLQGDRIKVYCFGRDGGQLAALRPDVSQLTETMAQAMALVAKVVLPGDRVLLSPACASLDQFRSFEHRGNEFARLAEELG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHLB2_CHICK
Sequence: MDFNVKKLASDAGVFFSRAMQFTEEKLGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMTEAANDFGPGTPYGKTLIKVGETQRRLGAAERDFIHSASINFLTPLRNFLEGDWRTISKERRILQNRRLDLDACKARLKKAKAAEAKAAAVPDFQETRPRNYVLSASASALWSDEVEKAEHELRLTQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTNYYAQCYQYMLDLQKQLGRFSGTFVGNAESTSPPPAAASPPAVAATTLPAVPTIPVVPTIVGVPNTVAESVLNPNEVKPPASGTRKARVLYDYEAADSTELALLADEMITVYSLPGMDPDWLIGERGNQKGKVPVTYLELLS
What are the official names of this protein?
Endophilin-B2, SH3 domain-containing GRB2-like protein B2.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PORG3
Sequence: MRKNIVAGNWKMNKTLQEGLALAKELDAALKGRTISCDVIIGTPFIHLASIAAAIDTTRIGVAAENCADKESGAYTGEVSAAMVASTGARYVIIGHSERRAYYHETSPILMEKVKLALSNGLTPIFCVGEVLEEREAGKHFEVVARQVEEALFTLDQTDFAKLILAYEPVWAIGTGKTATADQAQEMHAHIRKSIAAKYGKEVANGCSILYGGSCNAANAKELFSRADVDGGLIGGASLSVDKFLPIIEAF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDR33_YEAST
Sequence: MTLSLNTPPGVHCQPLKHQRIPLLQLQLKSQPKSQLKSQPNKVLALKLLPPTLVPLLRLCQLPVLCWLVLPLYCCNLLNLFFNIFLEKWLSTFPSIQLPQNRFISINKIFW
What are the official names of this protein?
Putative uncharacterized protein YDR133C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NFI_SALPC
Sequence: MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSAEPGALSPLMDKGEQLAWVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRWQEIQR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_STAAR
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: NIKE_ECOL6
Sequence: MTLLNVSDLSHHYAHGGFSGKHQHQAVLNNVSLALKSGETVALLGRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKAEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL2_SALTO
Sequence: MAIRKYKPTTPGRRGSSVADFAEITRSTPEKSLLTPLPKKGGRNAHGRITARHQGGGHKRQYRIIDFKRVDKDGVPAKVAHIEYDPNRTARIALLHFLDGEKRYILAPKDLKQGDIVESGPGADIKPGNNLPLRNIPVGMTIHNVELRPGGGAKLARSAGTGIQLLGREGAYATLRMPSGEIRRVDVRCRASIGEIGNADQSNINWGKAGRMRWKGKRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVNPQGKPEGRTRRKGQPSDRLIVRRRYATRKRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1672_COREF
Sequence: MGLGDKIRNTAEKASGKVKEATGKATDNEKLEAEGKTDQFKGNAKNTVENAKDTLRGN
What are the official names of this protein?
UPF0337 protein CE1672.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: CP138_MYCTU
Sequence: MSEVVTAAPAPPVVRLPPAVRGPKLFQGLAFVVSRRRLLGRFVRRYGKAFTANILMYGRVVVVADPQLARQVFTSSPEELGNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGKSMKNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILRAIFGAGGSELDELRRLIPPWVTLGSRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVIDKLIEAERADPNFADRTDVLALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLGWAFERLSRHPDVLAALVEEVDNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGEWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLETTTAAGERSHGRGVAFTPKDGGRVVMRRR
What are the official names of this protein?
Putative cytochrome P450 138.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CIRSY_SYNAS
Sequence: MAKWNPQKRVLNHEHTRFWRFELRDVDEPNLQKEVFPYDEVSRIDFDHRIIPIQPAEEIFITDTTFRDGQQARPPYTTQQIVDLYQMMSRLGGYNGIIRQTEFFLYSNRDKEAVRMCQDLGLQYPEITGWIRAAREDIPLVKEAGLKETGILTSVSDYHIFLKLNMTRSQALEEYLGIVKAILDAGIVPRCHFEDITRADIYGFCIPFAIELMKLREESGVDIKIRLCDTMGYGVTYPGASLPRGVDKLVRAFIDDADVPGRLLEWHGHNDFHKALINATTAWLYGCSAANSTLLGLGERTGNPPIEGLIIEYIGLMGKTNGIDTTVITDIANYFKNEIEYKIPSNYPFVGADFNVTRAGVHADGLIKSEEIYNIFNTTKILKRPIVPMITDKSGKAGIAYWINSHFGLSGDSTVDKRHPGISKINKWIADEYELGRVTTISTEELEAKVRKYMPELFMSDLERIKFKAAEAAIAVLRKIIDDPAMKTMQPELQEPVMQRFIEEYPSIQFAYVVDMNGKKTTRNITNIVDRAKYENYGVGTDQSDREWFIKPLQTGKLHVTDFYISKMTGALCFTVSEPITDDNDDMVGIFGVDIRVEDLVKEPEYIAEATQIALKAEYDAKYKSDHWL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with oxaloacetate to form citrate.
What are the official names of this protein?
Citrate (Re)-synthase, Re-citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: ISPA_BACSU
Sequence: MTNKLTSFLADRKKTIENQLSVYTEKLDMPDSLKKSMLYSLQAGGKRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHKVFGEATAVLAGDGLLTESFKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQVADMEAENRQVTLEELESIHERKTAKLLGFCVIAGAILADAPEEDIETLRTFSSHIGIGFQIRDDILDLEGSEEKIGKRVGSDTTNDKSTYPSLLSLEGAKHKLDVHIKEAKRLIGGLSLQKDLLYELCDLIAARDH
What are the official names of this protein?
Farnesyl diphosphate synthase, FPP synthase, (2E,6E)-farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_YERPY
Sequence: MTASASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIELLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_PARMW
Sequence: MALQPAAGARDLNPRQVESNRALSERLASVFRLWGYDEVSPPRVERLDTLMAGGAIASEDVVRLVADEPLGLRPEMTASIARAACTRLASRPRPLRLWASGTVFQSRAADEGGQCIEENLQCGVELFGVAPIEAEMELLSLLMAAVERLDFQAQHQPRLLMGHTGLMDLLLSPVPPVLRDAVRAALIQYDRLGLETIELEEGLRATLLSLLDCRGTPNEVLERLSSCFGAQALFDDLHRLCRQLQGPAAAQGVRLQLDPTFQPRFELYTGLVFQLVCDTHSAPVVVARGGRYDDLVRRCGAQPGQDFGAGFSLAIDPIRELLSDSSSNPTVAPQLMVAFSERSTLEAALERQRWWHQQGRSAVIELHPFSTRSLAEQQATDQGGFQLDWIDP
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_BACCZ
Sequence: MMRPVVVKEKRVNESQIHVVEDEVRQAKTMDRDIVTHAMKQSIAKLNPKVMIKNPIMFVVEIGFIITFILSFLPSSSSSIPGWFNITVSLILLFTVLFANFAEALAEGRGKAQADSLKQSKKDVFANVVKENGDIVQVSATDLRKGDVVIVKQGEMIPSDGEVIKGLASVDESAITGESAPVIKEAGGDFCSVTGGTMVVSDEITIVITSNPGESFIDKMISLVEGAARQKTPNEIALNTVLTSLTLIFLIVVVTLPIFTNYLGFQIDTAVLVALLVCLIPTTIGGLLSAIGIAGMDRVTKFNVLAMSGKAVEAAGDINTIILDKTGTITFGNRMAHTLLPVGNETIEQVGKWAAISSVLDETPEGRSVIEYVQAKSISYNRELAEQGEFVPFKAETRMSGVDLRDGTKVRKGAVSSVIEWVQSQGGTIPKDVNQKADFISKEGGTPLVVAVNDHIYGLIYLKDTVKPGMRERFEQLRQMGIKTVMCTGDNPLTAATIAKEAGVDEFVAECKPEDKIAVIKAEQDKGKLVAMTGDGTNDAPALAQADVGLAMNSGTTAAKEAANMIDLDSNPTKIIEVVGIGKQLLMTRGALTTFSIANDVAKYFAIIPAMFTLAIPQMEALNIMKLTSPLSAILSALLFNAVIIPLLIPLAMKGIAYKPMSSNALLGRNLLIYGLGGVIVPFIGIKVIDIIVGLFI
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOCD_YERPY
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHRQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PLP1_PLAFO
Sequence: MSDDDDKIYIYSDLFSKNFSDDEKDDSYEREKQVYSGSETQNAENEYSKLRAQNSTILNNYFDNDNIKNVENLKSNDPDQIDLILFPVNKNYYMNLFDGQLIENIHSIKLRKAGFYAIYVENNNNSKWDGIYFGLSRMQVELDYKLITKKNKDGGEYEKRNTSSYDNTESVQNTVGSEKEETENKNEETSNYNSNLNNEINKICKYNLDQTDILLDDSNSERRRNSKFKIKNTNYYDNLMLQNKYTNSILYDDDDDKNNTETYTCTFKTEDQIRVPSQKKKYIYLYNKYDNATLDLNVHTYMSLGMSILCKYSLLYCGKYNHIPRDPYTPFKKPVSILSLDGGGILTISTLLVLNRLEAELRKEIGSDDIKLIDCFDMVCGTSAGGLISLALLREIDLQDVSNMWPSTIKKVFEGNRNIISGIFFEGYDVNNVKDVFLERMGNKFMSSYKKFYCFVTATDVKHKPYKLFLIRNYTHKYNSINAESYDGINKVPLWLAAWATASAPTYLKGPSAEDIKKLGINIKPEIHLVDGALKASNPALIALEECARLNNKNLSTFIKEDLDTLVSIGTGQVPTKLTQSGASSKSASTFEILINSTHLLTRANDTHREVLQRLADRENTYFRFNVPHIGDIEIDSQDVRDFDLISKATQDYLFDEKFYEIKRLAHKLANNYIRSKYL
What is the function of this protein?
Hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids such as phosphatidylcholine (PubMed:31413195).  Involved in gametogenesis; however, it is not clear whether it is involved in gametocytes development in host erythrocytes or in gametocyte activation in the mosquito midgut (PubMed:31413195, PubMed:31734953).  Involved in gametocyte development in host erythrocytes; however, not involved in gametocytes activation including male gamete exflagellation (PubMed:31734953).  Involved in the rounding up of gametocytes following activation in the mosquito midgut; however, not required for gametocyte development in host erythrocytes (PubMed:31413195).  Required for exflagellation of activated male gametocytes (PubMed:31413195).  Involved in gametocytes egress from host erythrocytes by promoting the relocalization of perforin-like protein PLP2-containing vesicles to the periphery of gametocytes; PLP2 secretion is required for permeabilization of the erythrocyte membrane and thus, promotes gametocyte egress (PubMed:31413195).  Dispensable for asexual blood stage development (PubMed:31413195).
What are the official names of this protein?
Patatin-like phospholipase 1, PfPATPL1.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_AKKM8
Sequence: MSIESFANQHVLELVAYQPGKPIEETARELGLNPHDIVKLASNENPLGPSPKAVEAIARAAAGVNIYPDGAAFRLRSAIAEFCGVEFGQTVVGTGSSEVIELICHALLNPRAEVVAAKHAFSMYPIMSKLFGAAYVEVPNKEDWTHDLDGFLAAITENTRVVFITNPTNPVGTVVGQQEIDDFMAKVPEHVLVVFDEAYREFSDNPPDTLKFVREGRNVVVLRTFSKAYGLAGLRVGYGIAPEPVCSMLHKARAPFNLHVLAQEAALAALEDREHVRRTVENNKEGMRFYEQAFREMGLEWIPSQGNFILVKVGRGKQVFQDMLARGVIVRAQDGYGLPEWIRISIGTPAENARCIEVLKEVL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ALGX_PSEAE
Sequence: MKTRTSRLFRLSALAAGLCLAQAALAADPGAAPSYQALPAGNLCPAAAYDSRYNTKYLGFFTHLVQAQDDWLFRTTYDLRTDFGTSAEGWRELRALRDELKRKGIELVVVYQPTRGLVNREKLSPAEKAGFDYELAKKNYLATIARFRQAGIWTPDFSPLFDEKEEHAYYFKGDHHWTPHGARRSAKIVAETLKQVPGFEEIPKKQFESKRVGLLSKLGTFHKAAAQLCGNSYATQYVDRFETEPVGASDSGDLFGDGGNPQIALVGTSNSGPAYNFAGFLEEFSGADILNNAVSGGGFDSSLLAYMTSEEFHKNPPKILIWEFATHYDMAQKSFYRQAMPLVDNGCSGRKTVLSRKVKLRQGRNEVLLNSAALPIRSGSYVADVTYSDPSVHELKNTIWYMNGRREQLKIEQSKAVDTGGRYVFQLRNDSDWADQQFLSLEIEAPEDMPQGLEVQASICQAAPAKASQSVAGR
What is the function of this protein?
Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation.  Acetylation of alginate causes the cells in the biofilm to adhere better to lung epithelium, form microcolonies, and resist the effects of the host immune system and/or antibiotics.  Displays a low acetylesterase activity in vitro using a pseudosubstrate, 3-carboxyumbelliferyl acetate.  Probably has acetyltransferase activity in vivo.
What are the official names of this protein?
Alginate biosynthesis protein AlgX, Probable alginate O-acetyltransferase AlgX.
What is the protein family that this protein belongs to?
Belongs to the AlgX family.
What are the subcellular locations of this protein?
Periplasm.