PharMolix/UniProtQA huggingface dataset:
Protein: PSBK_EMIHU
Sequence: MDVNFLLSALPEPYAAFRPIVDVMPAIPVFFLLLAFVWQASVGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y604_ARCFU
Sequence: MPAWMIRNRVGKKLFDGYLVFCFERNPWAKVVSRYLYYKRFDKNFNLSFREFVKSNWIYDALNFPQYTDPLRNYKVIVDFIGYYENLEEDIAKVMKKIGLPEELDVRINTAADDNYRKIL
What are the official names of this protein?
Uncharacterized protein AF_0604.
Protein: LSRK_YERE8
Sequence: MSQFSTTTSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWKLTCQCIRQALHQANLPASAIRAVAACSMREGIVLYDRSGKPIWACANVDARASREVSELKELYNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAEAAQECGLLAGTPVVMGGGDVQLGCLGLGVVQPGQTAVLGGTFWQQVVNLPKPITDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGIPVRVPVVKEATALGCAIAAGVGVGLYEALDKTGEQLVRWEREYQPNIEHKALYQAAKTNWQAVYTDQLTLVDSGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KA281_ISOMC
Sequence: MNFWVTFIRLIVVLSIVFAFQIAVAKAACVTHEDCTLLCYDTIGTCVDGKCKCM
What is the function of this protein?
Selectively inhibits Kv7. 1/KCNQ1 channel (Kd=11. 69 uM) and inhibits Kv1. 1/KCNA1, Kv1. 2/KCNA2, Kv1. 3/KCNA3 with a very low potency.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 28.1, Toxin ImKTx104.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 28 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACSA_ECOL6
Sequence: MSQIHKHTIPANIADRCLINPQQYEAMYQQSINAPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDASQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVVVLKRTGGKIDWQEGRDLWWHDLVEQASAQHQAEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEEKQAIAMPS
What is the function of this protein?
Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.  Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HIS6_PROA2
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNGELADELVFLDISASLESRKTTLGEVLKVSEEVFIPLTVGGGISSVERAHDAFMHGADKVSVNTAAIATPELISRIAEKFGSQAVVVAIDVKKVGNDYIVHTHSGKKPTQYEAMEWAHKVEKLGAGEILLTSMDRDGTKSGYDNVILKAISTSVNIPVIASGGAGNLEHLYQGFAEGHADAALAASIFHFRQYSIREAKTYLRERGIVVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MELT_RAT
Sequence: MHQLFRLVLGQKDLSRAGDLFSLDDAEIEDSLTEALEQIKVISSSLDYQTNNNDQAVVEICITRITTAIRETESIEKHARALVGLWDSCLEHNLRPAGKDEDTPHAKIASDIMSCILQNYNRTPVMVLAVPIAVKFLHRGSKELCRNMSNYLSLAAITKADLLADHTEGIVKSILQGNAMLLRVLPAVYEKQPQPINRHLAELLALMSQLEQTEQYHLLRLLHVAAKRKDVEVVQKCVPFLIRNLKESTYNDIILNILIEIAGHEPLALNSFLPMLKEIAEQFPYLTGQMARIFGAVGHVDEERARSCLRYLVSQLANMEHSFHHILLLEIKSLTDAFSSILGPHSRDIFRMSNSFTNIAKLLSRQLENSKAESGRRRTGTEVSFPEKFREPKTMEPKSEDHEKLQVKIQAFEDKINAESHTPGSVRRYSLDHVSKEERKNVRFSRSRSLALNTVLTNSVNVEDGEIEGKTGMHASISLSEIDPPGHGIGKVPFKTDTHGSQLRNSSASHPSIIHSEPENMPETFKENVQEEIPEAAISPVEYQDKLYLHLKENLSKVKAYALEIAKKVPIPDQCTIEDNTRSCVAKLFFTCSLKGHYCLYSKSSFTLVSQAPQPWIQIMFLFQQSLFPEPLSIQSGSVQFLKALWEKTQGTGTHSFEVAMTESTFPQQKDLDQLQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVINQDGQPLIEGKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSDDPDDSPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVALAQAKERESREVTTYL
What is the function of this protein?
Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling.  May also affect FOXO, Hippo and Wnt signaling.
What are the official names of this protein?
Ventricular zone-expressed PH domain-containing protein homolog 1, Protein melted homolog.
What is the protein family that this protein belongs to?
Belongs to the MELT/VEPH family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GCSPA_PHEZH
Sequence: MRYLPLTPEDRAQMLGVIGAPDVDALFADVPAAARNPAIGLAPHAGELEVERELSGLAALNRAAGAGPFFCGAGAYRHHVPATVDHIIQRSEFLTSYTPYQPEIAQGTLQVLFEFQTQVARLTGLDVANASMYDGSTACAEAVMMAQRVTRREKAILSGGLHPHYAATTQTIAHAEGMEIVRQPAAIDAEAAVIEAIDAETACVVVQTPNVFGVVTDVSKIAEAAHAKGALLIVVTTEAVAYGLLKSPGEMGADIAVAEGQSIGNALNYGGPYVGLFACREKFVRNMPGRLCGETVDAEGRRGYVLTLSTREQHIRREKATSNICTNSGLCALAFSIHLSLLGGKGLSQLARVNHARARELKAAVEAAGLEVLTPRFFNEIAVRTKGPAADLVERLLADGVVAGVPFSRLDPGAGLDDVLLLCATETTTSDDIAALKDALAR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: HIS4_PARDP
Sequence: MILYPAIDLKDGNCVRLLRGDMEAATVFGTDPAAQARAFRDAGAEWLHLVDLNGAFAGKPVNAAAVEAILAAIDLPVQLGGGIRDMATIEGWLDRGLARVILGTVAVEQPELVREAAMAFPGKIAVGIDARGGRVATRGWAEETDVNVVDLAHRFEDAGVAAIIYTDIDRDGAMAGPNIAATEALARAVNVPVIASGGVSSMQDLMALRATGVIAGAISGRALYDGAIDLNAALKALA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUNB_DROVI
Sequence: MPNWETSTAAPSYEQHNAWYSSMFAANIKQEPLSHHHHHHGQQHHDNHSNSNSGASSPRQSPLPSPIPPSTQLEQYLKQQQQQQQQQQQPMDTLCAAAMTPSPSNNDQNSLQHFDATLQQQLLQQQQYQQHFQAAQHQQQQHHHLALGGFNPLTPPGLPNPMQHYYGGNMRPSPQPTPTAAPTAVAAAIQTGDKLQALTPPMDVTPPKSPAKSQQSSAEPEKEHDLMSNSSEDMKYMAESEDDDSNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCAKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKSFSGSGSSCSSTSKRSNASAAAAQQQQQPVATSQLSAALQGFPMPAAAAGTAAGAAGTAAPAAVAPVSPPSPAKSVASVEQAPSLPSALLPPLASLLQQNRNMAFFPYWNLNLQVLAAQQQAAVLAQLSPRMRDQLQQQQQQQHQQQQQQQQQQQQQQQQLPAHSENEEDEEEEEHEDDFERKSVDSAMDLSQGTPVKEEPQQQQQQQQLPHSNHMAINLKLKDEDTPLISSSSASRRKGRVLKLDTLLQLKSAAMSSPEQQLKLPASVLPTASSPIAGSSANKQLADDPCSGASSADESMETGRVPQVNISASSTASSSGNSSNASSSTSNPTAAATVATSGTVSSSSSSSTTTSSSAPAIYECKYCDIYFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KLD10_DROME
Sequence: MNILNPGKFKCIVFDQLRHTWTFLLFICDFLAKIYRTPRITAHQEQLANHNNNNNNNNDLIMEQDMPEEEVGQPEEALPQQDNGEVVDRFNAIQAAVELMDAASDLDEEEEEEDDDVDVDVDYGDTDSESEFEEMYSDEWTSSSDELDEGTELSKSVLNVFLSSDKQQSQMAGQIPMYAFQPLRLVKCQYRDKHIPGGFPLARSGHRIIASNSHLYSLGGYNPRSAMSASRHGRCLLFQELWSYNFATRTWRLELNAGNAANMPVELASNALTIHNNVLISHGGTGYPFGVSCSNDCYVYRTASAGATPGVDRLQVKGDLPTAQYGPGIVIHKHFLYTIGGTTGFDYTCDVYRLDLRTGIWENVYISRPEMRDDPEGRYRHEVVYDGKHIFVLGGGTSHSVYDLQRIPAYNLEANCWDYFETYPDQRAADADDGNRGYPKPRKCFSCVQHQSSTGDIEAFITGGLQGDFSTYFSDIWKLNLRTKHWYRIETAILPRPLYFHSAAHSDNGCMYVFGGIEYIDKEMRRRNDLYKMWMTVPKLSEMCWDAITYYNDNLDLYDRKTLLEAGIPKRFTERLPPQRRRRLDTSQPDPSMLISLYSNPKRARSSTQ
What is the function of this protein?
Activates the Pk92B/DASK1-MAPK signaling cascade.
What are the official names of this protein?
Kelch domain-containing protein 10 homolog, Scruin like at the midline.
Protein: WN10B_DANRE
Sequence: MELPHRQCLGRVLIVTAALLSPAFTVLGNDILGLKVAGEPVLTPNAVCLRLAGLTKKQMRLCVRSPDVTASALQGIQVAIHECQHQLRDQRWNCSSLENHGKLPHQSAILNRGFRESAFSLSLLAAGVVHSVASACSLGKLRGCGCEAKRRLDDDKIRLKLTQLQLQTFQRSGVSLAGAGENTPELSSLHGSLPANLHSSHPMSLLKPLPDEVTMLQDTWEWGGCSHDIRFGVRFSRDWLDSRGSPRDIHARTRIHNNRVGRQVVTDNMRRKCKCHGTSGSCQFKTCWYVSPEFRLVGSLLREKFLTAIFINSQNKNNGVFNSRTGGSTGSDPLRGQRRRSISRELVYFEKSPDFCDREPAVDSLGTQGRICNKSSPGMDGCGSLCCGRGHNILKQARSERCHCRFHWCCYVLCEECKVTEWVNVCK
What is the function of this protein?
Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade.  Involved in neurogenesis.  Performs a partially redundant function with wnt1 in the formation of the midbrain-hindbrain boundary (MHB) organizer.
What are the official names of this protein?
Protein Wnt-10b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: SCRY2_OCTVU
Sequence: MPSYTLHYFNHRGRAEICRMLFAAAGVQYNDRRVDCSEWTGMRNQMPCSMMPMLEIDNRHQIPQSMAIARYLAREFGFHGRNNLDMARVDFISDCFYDILDDYLRMYHDKDGRMMFQRSYDNGSSSERRMRFQETCRRILPFMERTLEMRNGGNQFFMGDQMTMADLMCYCALENPLTDDTSMLSSYPKLQALRNRVMSHMKMSPYLKSRSSTDF
What is the function of this protein?
S-crystallins are structural components of squids and octopi eye lens.  Contains relatively little GST activity (1/1000 of that of mammalian GST enzyme).
What are the official names of this protein?
S-crystallin 2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: TRUA_GLOVI
Sequence: MSVDAVGGAVEGAPARLALRVQYLGGHFFGWQWQPGQRTVQQCLEEATERIARHPVRYHAAGRTDTGVHASGQVVHFDTHKKLAPETWVRGLNSLLPDDIAVRAAAYVSDHWHARFTALWREYRYCIHNSTVPDLFVRAQSWYYPYCPLDSEAVAAALATLPGHHDFRAFRRAGSSRPHSLVHVYTAECTREGEQIAIRVRANSFLYGMMRLLIGALAEVGSGRWSVERFAGLWQAGNREQVKYAAPPQGLCLVGVGYPDDPFKTNGIGFARCHTGQEKPEARLGNGDLESREERPPHEMSPLH
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YG194_YEAST
Sequence: MSNKEITCIKPFKIIALILLIVLIINLSYKLFLRRYLKSTVIWCLGIANTDRNDMMWWQVSPLLERWVWQLVDNYESGYE
What are the official names of this protein?
Uncharacterized protein YGL194C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDC_BORPE
Sequence: MDIRRTVLWMIFSFSLLLLWNNWQIHNGKPSLFGGPAPEAAATQQPKADANGTAASSTASIPSSPAAAPAAASVPGAAAPAAAKSEQVVITTDVLRLTFDSNGAQLIRAELLKYPSSSQSDKPTVLMDRSADLVYVAQTGVVGAPQGESFPTHQTPFHLVSSERSLTGDTLDVVFEAESGGLKVTKTYTLHRGRYDVDVRHAMANTGGAPLNPALYLQLERDGTDPAGTSSFYHTFTGVAVYSEQDKFQKVTFSDIEKKKGTYIKQADNGWIGIVQHYFATAWIPAQGKQRTNELLQVQQNLYAARTIEAVGTIAPGSSANVDAHLWVGPQDQKAMAAVAPGLELVVDYGWLTIIAKPLFTLMTWLHGLLGNWGWTIVALTVIIKAVFFPLAAASYRSMARMKQVAPRLQALKEKYGDDRQKLNQAMMEMYRTEKINPLGGCLPMVVQIPVFIALYWVLLASVEMRGAPWILWVHDLSVRDPFFILPAIMMATMFLQIKLNPTPPDPVQAKVMMIMPLVFGGMMFFFPAGLVLYWCVNNTLSIAQQWTITRNLERQAAAAANR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OS9_HUMAN
Sequence: MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF
What is the function of this protein?
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD).  May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation.  Possible targets include TRPV4.
What are the official names of this protein?
Protein OS-9, Amplified in osteosarcoma 9.
What is the protein family that this protein belongs to?
Belongs to the OS-9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: QUEA_RALSO
Sequence: MLTLSDFDFDLPPELIAQTALPDRTASRLLAARHDAQGTHFDDRQFADLVDYLRPGDLLVFNDTRVIKARFFGHKASGGKIEVLVERLLDEHTVLAQIRSSKSPVAGSTLRLADAFDVTVGPRHEPFFTLRFPQPALELIEQYGRLPLPPYIEHTPDSFDETRYQTVYARTPGAVAAPTAGLHFDDALFARLDAMGVRRGFLTLHVGAGTFSPVRVENIAEHRMHSEWYAISPDLAEAIRATRAVGGRIVAVGTTSMRALESAAQPDGTLAAGSGETDIFITPGYRFRLVDALVTNFHLPKSTLLMLVSAFAGLETIRAAYRHAIAQRYRFFSYGDAMFLTRAEPDTQSASPDPSC
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALKB1_PSEAE
Sequence: MFENFSPSTMLAIKKYAYWLWLLLALSMPFNYWMAQDSAHPAFWAFSLVIAVFGIGPLLDMLFGRDPANPDEETQTPQLLGQGYYVLLTLATVPVLIGTLVWAAGVFVAFQEWGWLGRLGWILSMGTVMGAVGIVVAHELIHKDSALEQAAGGILLAAVCYAGFKVEHVRGHHVHVSTPEDASSARFGQSVYQFLPHAYKYNFLNAWRLEAVRLRKKGLPVFGWQNELIWWYLLSLALLVGFGWAFGWLGMVFFLGQAFVAVTLLEIINYVEHYGLHRRKGEDGRYERTNHTHSWNSNFVFTNLVLFHLQRHSDHHAFAKRPYQVLRHYDDSPQMPSGYAGMVVLALIPPLWRAVMDPKVRAYYAGEEFQLTAEQSERPAAS
What is the function of this protein?
Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin.  It preferably hydroxylases C16-C24 hydrocarbons.
What are the official names of this protein?
Alkane 1-monooxygenase 1, Alkane hydroxylase, AHs, Terminal alkane hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RAD16_SCHPO
Sequence: METKVHLPLAYQQQVFNELIEEDGLCVIAPGLSLLQIAANVLSYFAVPGSLLLLVGANVDDIELIQHEMESHLEKKLITVNTETMSVDKREKSYLEGGIFAITSRILVMDLLTKIIPTEKITGIVLLHADRVVSTGTVAFIMRLYRETNKTGFIKAFSDDPEQFLMGINALSHCLRCLFLRHVFIYPRFHVVVAESLEKSPANVVELNVNLSDSQKTIQSCLLTCIESTMRELRRLNSAYLDMEDWNIESALHRSFDVIVRRQLDSVWHRVSPKTKQLVGDLSTLKFLLSALVCYDCVSFLKLLDTLVLSVNVSSYPSNAQPSPWLMLDAANKMIRVARDRVYKESEGPNMDAIPILEEQPKWSVLQDVLNEVCHETMLADTDAETSNNSIMIMCADERTCLQLRDYLSTVTYDNKDSLKNMNSKLVDYFQWREQYRKMSKSIKKPEPSKEREASNTTSRKGVPPSKRRRVRGGNNATSRTTSDNTDANDSFSRDLRLEKILLSHLSKRYEPEVGNDAFEVIDDFNSIYIYSYNGERDELVLNNLRPRYVIMFDSDPNFIRRVEVYKATYPKRSLRVYFMYYGGSIEEQKYLFSVRREKDSFSRLIKERSNMAIVLTADSERFESQESKFLRNVNTRIAGGGQLSITNEKPRVIVDLREFRSSLPSILHGNNFSVIPCQLLVGDYILSPKICVERKSIRDLIQSLSNGRLYSQCEAMTEYYEIPVLLIEFEQHQSFTSPPFSDLSSEIGKNDVQSKLVLLTLSFPNLRIVWSSSAYVTSIIFQDLKAMEQEPDPASAASIGLEAGQDSTNTYNQAPLDLLMGLPYITMKNYRNVFYGGVKDIQEASETSERKWSELIGPEAGRRLYSFFRKQLKDYE
What is the function of this protein?
Endonuclease that specifically degrades single-stranded DNA and which is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.  Required for double strand break-induced interchromosomal gene conversion.
What are the official names of this protein?
DNA repair protein rad16.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: PTUB_BACTU
Sequence: MIHLKRPNSPSKLINEEAKLTQEFLQNGNSVWGKPYIKLALLEMSNNKCVYCECRLDEESKYMEVEHFLPKDTYPNLVVNWRNLLPSCKRCNGKKGTHDSKKEPIINPTVDTPSNHIKMFNYCLKGKDLKGKTTVDVLHLNQLDRLVYPRMLIGTKTIETVEKLLEMAENFNLNINATGRIKSRIIHGTTQLLIEAQPHSEYSATVASVLFNNEDFVKLKEIMIKCTIWNTEHQKLLSNAERNILVEPLYNCLNNKN
What is the function of this protein?
Component of antiviral defense system Septu type I, composed of PtuA and PtuB.  Expression of Septu type I in B. subtilis (strain BEST7003) confers resistance to phages SBSphiC and SBSphiJ (PubMed:29371424).  May be a nuclease (Probable).
What are the official names of this protein?
Septu protein PtuB, Putative nuclease PtuB.
Protein: MURB_SYNY3
Sequence: MIISPATRPTPMETPAIALAGTGTIIQPETSLAEFTTYRVGGKAEWYAAPRCLEDLVAVLDWFQGQDLPLTFLGAGSNLLISDQGLAGLVLSTRYLRQSKFDEEQGLITVAAGEPIAKVGWQAAKRGWQGLEWAVGIPGTVGGAVVMNAGAHNQCTAETLVEATVMRPDGGLEVLTNEQLGFSYRTSNLQKHLGDRLVVDATFKLTPGFTREEIMGCTTRNLHQRKSTQPYDKPNCGSVFRNPTPLYSARLIEELGLKGYRIGGAEVSQRHANFIVNIDNAKAQDVFNLIFHVQGEVEKHYGILLEPEVKMLGEFAR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_STAAN
Sequence: MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ARLY_BACAA
Sequence: MSKLWGGRFTEEAEAWVEEFGASISFDQQLVNQDINGSIAHVTMLAKQGIVTKEEAEKIKIGLQYLLEEAKQNKLHFSVEAEDIHLNIEKMLMEKIGEVGGKLHTGRSRNDQVATDMHLYLKEKVEHIIKAIKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALAGTTFPIDREYSAELLGFNGIYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQEFQFIEMSDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTVEGCLHIMAGMLETMTVNKEKMGQAVTQDFSNATEIADYLANKGLPFRQAHEIVGKLVLHCTQKGIYLIDVPLATYKEMSALFEEDLYEVLSPYAAVKRRNSAGGTGFEQIEKALEKAKGLTKEAIKN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5248_MYCGI
Sequence: MADSSFDIVSKVDRQEVDNALNQAAKELATRFDFRGTDTTIEWQGEEGIILVSSTEERVKAAVDVFKEKLIRRDISMKAFDAGDPQPSGKTYKVIGSIKQGISSEDAKKVTKLIRDEGPKGVKAQIQGEEIRVSSKKRDDLQAVQALLRGADLDFAVQFVNYR
What are the official names of this protein?
UPF0234 protein Mflv_5248.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TRMFO_NITHX
Sequence: MTQIELSCSAVHIIGAGLAGSEAAWQVANHGVRVVLHEMRPHRMTAAHQTGGLAELVCSNSFRSDDAANNAVGLLHAEMRRLGSLIMRCADANQVPAGGALAVDRDGFSSAVTKALDDHPLIEINRTEVDGLPPADWRNVIVATGPLTSAPLAAAIRALTDESALAFFDAIAPIVHRDSIDMSKAWFQSRYDKVGPGGTGADYINCPMTEAQYHAFVDALIEGEKVDFKDWEIDTPYFDGCLPIEIMAERGRETLRHGPMKPVGLTNPHDPTVKPYAIVQLRQDNRLGTLYNIVGFQTKLKHGAQTRVFRTIPGLETAEFARLGGLHRNTFLNSPKLLDTQLRLRAEPRLRFAGQMTGCEGYVESAAIGLIAGLYAASDARARSLAAPPPTTALGALLGHITGGHIESIDAGPRSFQPMNINFGLFPPLANPPAKKPDGTRLRGNEKTIAKKQAISARALADLDRWIADALRVAAAA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_LISMF
Sequence: MLQPHLVIGSAFTFGDAFFTLFAFAILLVLIRIYAWKPLMGVMKEREEHIGSEIDAAEESRAQAEQLLAEQKSVLQQARVESQTMIENAKQLGEKEREEIVKTARRESERIKEEAKSDIAREKEDAISALREQVGSLSVLIASKVIEKNLDEKEQSNLIQDYIERLGDDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS7_VIBC3
Sequence: MPRRRVIGQRKILPDPKFKSELLAKFVNILMVDGKKSTAEKIVYTALDTMAEKSGKDHLAVFEEALENVRPAVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAARLAAEMLDAAENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.