PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_EDWI9
Sequence: MSLNFLDFEQPIAELEAKIDSLNALSRQDEKLDINIDEEVQRLREKSVELTRKIFADLGAWQIAQLARHPRRPYTLDYIQHIFTDFDELAGDRAYADDKAIVGGMARLDGRPVMVIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNLPIVTFIDTPGAYPGVGAEERGQSEAIARNLREMSGLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGITAPRLQELKLIDSVIPEPLGGAHRDPQAVAASLKTQLLADLEDLDTLEKEELLDRRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCL2_ASPFU
Sequence: MASTVSTCQDASPYQPRNYQLEMLEASMKENIIVAMDTGSGKTHIAVLRIKAELDICSPDKVVWFLAPTVALCIQQHEVIASNLPAVRTRTLTGLDKVELWTDQSIWDAVLNGYRVIVSTHAVLADALSHGFVKMSQLALLIFDEAHHCTRRHAANKIMQDFYHPTLTKSGPAAVPRIMGLTASPVVRSNHQELLMVESNLDAVCRTPRLHRQELLKFTHRPHLQQIWYTPTDPAGFRSASLTLGALYHAWENLDIGDDPYIQRLRKSPLDDRALKKALLTGKTYCREQLRRFVDRSRHIFEELGEWAAEYYIYASIKQLRDRVRDSYMSGDWDEAEKAYLVDFLSKIPTSDIHFALNDPDGFRISPKFESLLNFLDSSDQREFSGLIFVKQRVTVSAMTSLLSVHPYTRERFRCAAYVGWSNSSASKDILGDLLNMQLQRDTLDDFRSGRKNLIIATDVLEEGIDLSACSVVVCYDKPPNLKSFIQRRGRARRKQSTFAIMFPTDDTSADVSRWQDLEQAMIEAYQDDERQLQSVSALESLDEEVMERLTGDSTSAVLTADMAMAHLHHFCAVLPPQPYVDMRPVFSFETNEDGLLKGTVILPSCVHPKVRRTEGRRWWRTERAAMKETAFQAYKSLYEFGLVNDHLLPLTKKPELKTHDLGSMPSILETSEQYDPWIEWAYSWSSPDIHQSRIVVKMNEGRGDELCMRLIGPEYLPPLSPMTLFWNSSTTFTVTFKAAERVPLVPLSSVEDMRAITALYLKATSSRVCSAERDFMALFAPDLHHTELKGWLDTYEGSDPAMEVYSRGHNPLLMGVVRDHSRYGEPFLFRKWLVSHQNPSCSIVELECAPFPHRRNFLRRQTLANSQVDVDEAIPDSAAKNPIVAAEACTIDRLPFTMAIFGLFISAIVEQLEIELIATRLRDTILRDVSFKSTDHIITAISTPLAHRLTNYQRYEFLGDSILKFSVSCQLFFQHPNWHEGYLSEGRDMIVQNPRLAKAALDTGLDAYIVTKRLASRKWSAPLISEKLGRVPAKRQMSTKVLADVVEALIGAAYVDGGHSTAQACIRRFLPEINLHAVDTRTAARSVAPESARHMMNDRLKDHIGYTFEDESLLVEALTHPSCDYDSTTQSYQRLEYLGDAVLDMVIVSAIFNHRIQRPQGDMTKIKHAVVNANLLAFLCMEFAISEEKLDVAQTSKDSFAVTSSQESVELWRFMRYRGQGLKAARDASLARHRALRDEIASSLLQAPHYPWHALSRLNADKFFSDIIESVLGAIFVDSGGNLAPCEVFVEQIGLMAYLRRILDHGIDVRHPRSVVQQLAKTNIQFVLQRVPTEEGGASYQCSVQMEQAELFVVTGCLTAEEAEVTAAVEAIKFLTRDEGSTPLNKS
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: RS7_STACT
Sequence: MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDIVQERSGRDAIEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLRWLVNYSRLRGEKTMEERLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PGK_GEOKA
Sequence: MNKKTIRDVEVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGAKVILASHLGRPKGKVVEELRLDAVAKRLGELLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFYPGEEKNDPELAKAFAELADLYVNDAFGAAHRAHASTEGIAHYLPAVAGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIDNLLEKVDNLIIGGGLAYTFVKALGHDVGKSLLEEDKIELAKSFMEKAKEKGVRFYMPVDVVVADRFANDANTKVVAIDAIPSDWEALDIGPKTRELYRDVIRQSKLVVWNGPMGVFEMEAFAHGTKAIAEALAEAPDTYSVIGGGDSAAAVEKFGLADKMDHISTGGGASLEFMEGKQLPGVVALEDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMK3_HALP7
Sequence: MPVAVGVIQTDGFPAVLAAADAMVKAASVTLVSFDKAERAQFYVAVRGPVSEVERSMEAGIAAAEETYNGTVITHYMIPNPPDNVETVMPIAYSDEVEPFRV
What is the function of this protein?
A probably non-essential, minor shell protein of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  Hexamers form sheets that form the facets of the polyhedral carboxysome.  In PCC 7418 there are several CcmK paralogs with presumably functional differences.  This subunit probably only makes heterohexamers with CcmK4.  Heterohexamers can also make dodecamers, formation depends on buffer conditions.
What are the official names of this protein?
Carboxysome shell protein CcmK3, Carbon dioxide-concentrating mechanism protein CcmK3.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family. CcmK subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: RSMG_CAUSK
Sequence: MSANLAPQIVEQLDPVDGPAFQRLTGCTDAQLADLTRFQALLTEWNEVMNLVGPATLPTYWNRHAWDSAQLLKLAPDARTWADLGAGAGLPGVVLAILLKGTPGAKIHLVESMTKRCKFLRAVADALDLPVEIHNARAEELDLKVEIVTARACAPMVRLLGYAQPYLKRGATAWFLKGQDVASELAEAATYWKFESDLRPSLSDPRGQIVQVKGLKSVRKV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF09_ARATH
Sequence: MKSSMQLISTLFFLVILVVAPGMKMVVEGQPQLCETKSLNYRGLCLKWRSCKRVCISEGFPDGRCKGFFNNKCVCRKPCALLSTEN
What are the official names of this protein?
Putative defensin-like protein 9, Putative low-molecular-weight cysteine-rich protein 76, Protein LCR76.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SK1_PSEFO
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, PseFo-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPE_ANAPZ
Sequence: MSKYFISAPAKINLFLHIVGKAPCGYHLIESVFAFVELYDVLEFDIGSRNRGIRFLKPSCINRRDNTIQRAIGHLVRRCSPGTTDNVYVKVLKNIPVSSGLAGGSADAAAAINLLSKLWGINEKETERVAFRVGSDVPVCLESKTAFVAGMGDVVELLEDSFLPRHVILVGPKVELSTKSVFDMYNPKAFSPSIGKLPGNSEDWLSLLKEARNDLTEVSVELVPEIRIILDVLGSLDGCCFSRMSGSGAMSFAIFEDENSAELATRYLRRNYPDWFIFKTRIIRSSDQEDNNMGNL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: DCD_PYRHO
Sequence: MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVSGKLIDVEKEGKVVIPPREYALILTLERVKLPDDVMGDMKIRSSLAREGILGSFAWVDPGWDGNLTLMLYNASNEPVELKYGERFVQIVFIRLEDPPRNPYSGNYQGSTRLVFSKRKKL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PSIP1_BOVIN
Sequence: MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQASAKQSNASSDVEVEEKETSVSKEDTDPEEKASNEDVTKAIDITTPKAARRGRKRKAEKQVETEEAGVVTTATASANLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDMITEEDKSKKKGQEEKQPKKQLKKDEEGQKEEEKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQDSNQPQHNGDSNEESKDNHEASSKKKPSSEERETEISLKDSTLDN
What is the function of this protein?
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis.  Involved in particular in lens epithelial cell gene regulation and stress responses.  May play an important role in lens epithelial to fiber cell terminal differentiation.  May play a protective role during stress-induced apoptosis (By similarity).
What are the official names of this protein?
PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL32_SYNY3
Sequence: MAVPKKKTSKAKRDQRRAHWRRQASSQAQKALSLGKSILSGRSTFLYPPAEEEGEEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RL24_EHRRG
Sequence: MGMKIIAGDDVLVVSGKDKGKMGKVIKVLKKKSCGKDLTFAIVSGINICKKSVKATQNSDGGIISVERPINISNIALVDSVLGIRTKVGYKFIDDKKVRFMKSSGKVIE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ATPH_CRYJA
Sequence: MNPLISAASVIAAGLSVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PROF3_HEVBR
Sequence: MSWQTYVDEHLMCDIDGHHLTAAAIIGHDGSVWAQSSSFPQFKPEEVAAIMKDFDEPGSLAPTGLHLGGTKYMVIQGEPGAVIRGKKGSGGITVKKTGQALIIGIYDEPLTPGQCNMIVERLGDYLLEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Hev b 8.0201.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YN64_YEAST
Sequence: MNPRRPYPVIFLCRPSSVASSKLASTFMISFLVKKTLSSNTVNSPRGTVRSISRIRNMVSLLLLPTIYIRSLVSYNVYLPITNLEVFLCLDPDVVSIPPPRVCSIASLFILVLFLFCFALRYYVSKLINFK
What are the official names of this protein?
Putative uncharacterized protein YNL324W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSCL_EXISA
Sequence: MWKEFKKFAMRGNVIDLAVAVVLGAAFTAIVNSLVNDIFMPLLGIIIGGIDFSSLKASILGVDVLYGNFIQQIVSFFLIAIALFLIVKVINRLQREKEVEEAAIPTPTKEEQLLTEIRDLLKDRSL
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URED_FRACC
Sequence: MAAMRRGVILGGVAAGPEGPLVTAARTGRTAVRARAVIRVESAPDGTARLIELRSDVPIVLRQTGASPGRTRAPSTVPALSADALPTATVHLVNATAGPLAGDDLGLDISVGSGVRLVVRSVAATVALPGHGPGPSRFTVSARVAPGGALDFAPEPTVAARGSDHLLVTDVHLATTAWLRLREEIVLGRFGETTGSIRSTLRVDMDAHAEVDPPSEPTPLLRQDLVLGPEIPGLTGPALLGSARALGSLLVAGPDPVGSPAARRESVPAKRAESGAQAAVADGVALLPLAGPGYLISALAENAVTLRRRLEQGPAPATV
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2C_DROME
Sequence: MAQNISPEQSGGAGGGGSKHSDDSMPVKDNHAVSKRLHKELMNLMMANERGISAFPDGENIFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAAPVVKFLTSCFHPNVDLQGAICLDILKDKWSALYDVRTILLSIQSLLGEPNNESPLNAQAAMMWNDQKEYKKYLDAFYEKHKDT
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by initiating polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 C, (E3-independent) E2 ubiquitin-conjugating enzyme C, E2 ubiquitin-conjugating enzyme C, Ubiquitin carrier protein C, Ubiquitin carrier protein vihar, Ubiquitin-protein ligase C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: Y546_MESFL
Sequence: MGRAHEVRAASMAKTAAKKSAANGRASKEIYMAAKAGGSDPSSNLALRALIDKAKSNQIPKEVIDRAIKRATGGDAENYVSNRYEGMGPGNTAIIVDALTSNVNRAAANIREVFNKNHGNPEGKVAFMFEEVSMFAFKGKTEEEVLEQLMMSEVDVNDVEVEEDMIIVTAPYKSFNAVKHSLDELGIEEYLMSEIKLIPIDDYIEVSDAELKQQLQTLLDKLDELEDVQNVYHNATI
What are the official names of this protein?
Probable transcriptional regulatory protein Mfl546.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_PELNE
Sequence: MSRYRGPRTKIIRRLGALPGLTSKILELESGYIGQSTPNKKVSQYRIRLEEKQKLRFHYGLTERQLLKYVRIARKAKGSTGQILSQTLEMRLDNIIFRLGMSPTIPGARQLVNHRHILINDNTVDIPSYNCEPKDVITVNNRKESVIIKNMDSSRKPKVPNHLTFDSIRFRGSVNQTIDRECIDLKINELLVVEYYSRQV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFP2_CHLPN
Sequence: MVRVSTSEFRVGLRIEIDGQPYLILQNDFVKPGKGQAFNRIKVKNFLTGRVIERTYKSGESVETADIVERSMRLLYTDQEGATFMDDETFEQEVVFWEKLENIRQWLLEDTIYTLVLYNGDVVAVEPPIFMELSIAETAPGVRGDTASGRVLKPAVTNTGAKIMVPIFIDEGELVKVDTRTGSYESRVSK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P 2, EF-P 2.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLRF2_EBVG
Sequence: MSAPRKVRLPSVKAVDMSMEDMAARLARLESENKALKQQVLRGGACASSTSVPSAPVPPPEPLTARQREVMITQATGRLASQAMKKIEDKVRKSVDGVTTRNEMENILQNLTLRIQVSMLGAKGQPSPGEGTRLRESNDPNATRRARSRSRGREAKKVQISD
What is the function of this protein?
Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA.  Acts by inhibiting CGAS-DNA phase separation: directly binds double-stranded DNA (dsDNA) in a length dependent but sequence independent manner and is able to form DNA-induced phase separation in infected cells.  DNA phase separation of ORF52 mediates disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity.
What are the official names of this protein?
Tegument protein BLRF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BLRF2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm.
Protein: HTPG_PASMU
Sequence: MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEGDGDLKVRIRFDEEKGTLTISDNGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGEGEYSVADIDKKERGTEITLHLREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRAKNEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAQVFMPNYLRFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRALQMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIAKLLRFASTHNDSSQQSVSLEDYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGKPLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPAVVSTGDDQMTTQMAKLFAAAGQAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLLEQAMLAERGSLENPVAFIKRMNTLLSKLTSH
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTC2_YEAST
Sequence: MGDHNLPDFQTCLKFSVTAKKSFLCMYRDSVSKEKLASSMPSTCDIQLKRAINDAYPGGGIKVTVLNSTTASLDSLATTHVKEFEIVIIPDINSLLQPDQAKLVKIMRDCTVAIEKAQSTRIFIGVVHWNNPVQPSGAAKDGDEAGKPAPKTRIFLPTSFRMGAWLKHKFWFACAPPYLDFESSTESSINTRANNSIGMAEEEKQEPESKRSIILNEEANLNDVFVGSTVRRYILDIMVHLRTHRLTYNAKAGGVYTNSLDDVVLLSRLIGLHSGKMFVSPSHVKEASRWYFPMHLELVQRSSMDSSLLYGSDPNLVDEMLEKLAKIKCEEVNEFENPLFLESLVVKNVLSKVVPPV
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 2.
What is the protein family that this protein belongs to?
Belongs to the MTC2 family.
Protein: PI3R4_HUMAN
Sequence: MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLNSAQNCLPFQKASEKASEKAAMLFRQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRTRGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIEDHSIRELVTQMIHREPDKRLEAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGHDLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLAETALRFLELVQLKNLNMENDPNNEEIDEVTHPNGNYDTELQALHEMVQQKVVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDSIVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALYALTCMCQLGLLQKPHVYEFASDIAPFLCHPNLWIRYGAVGFITVVARQISTADVYCKLMPYLDPYITQPIIQIERKLVLLSVLKEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMTEEEEDKLLALKDFMMKSNKAKANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEPDDKRARKHVKQDSNVNEEWKSMFGSLDPPNMPQALPKGSDQEVIQTGKPPRSESSAGICVPLSTSSQVPEVTTVQNKKPVIPVLSSTILPSTYQIRITTCKTELQQLIQQKREQCNAERIAKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIWNSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLKSGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWVIAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAGSDMKIRFWDLAYPERSYVVAGSTSSPSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRRGPESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK
What is the function of this protein?
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis.  Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123).
What are the official names of this protein?
Phosphoinositide 3-kinase regulatory subunit 4, PI3-kinase regulatory subunit 4, PI3-kinase p150 subunit, Phosphoinositide 3-kinase adaptor protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor. Note=As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes. Localizes also to discrete punctae along the ciliary axoneme (By similarity).
Protein: MDH_FRAP2
Sequence: MARKKIALIGAGNIGGTLAHLSLIKQLGDVVLFDIAPGMPQGKALDLLQSCPIEGVDFKVRGTNDYKDLEHSDVVIVTAGVPRKPGMSRDDLLGINIKVMQAVGEGIKHNCPDAFVICITNPLDIMVNMLQKFSGVPDNKIVGMAGVLDSARFRTFLADELNVSVQQVQAYVMGGHGDTMVPLTKMSNVAGVSLEQLVKEGKISQERLDSIVARTRNGGGEIVALLKTGSAYYAPAAAGIQMAESYLRDKKMILPCAAKIKAGMYGVDEDLFVGVPTEISANGVRPIHVEISEKEKEQLQVSINAVKELNKAAAEILAN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: ECHD3_MOUSE
Sequence: MAVVAGLRAFGVKWPSWLRRNPWAPLSAGFCSPGSAGPAGSESEPRLTSTRQQDGIRNIVLSNPRRRNALSLAMLKSLRSDILHEAESEDLKVIIISAEGPVFSSGHDLKELTDAQGRDYHAEVFQTCSEVMMLIRNHPVPILAMVNGLATAAGCQLVASCDIAVASDKSSFATPGVNVGLFCSTPAVALGRAVPRKVALEMLFTGEPISAQEALRHGLISKVVPEEQLEAETMRIAKKISSLSRSVVALGKATFYKQLPQDLRTAYFLASQAMVDNLALQDGQEGIEAFIQKRKPIWSH
What is the function of this protein?
May play a role in fatty acid biosynthesis and insulin sensitivity.
What are the official names of this protein?
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HTOMT_CATRO
Sequence: MDVQSEEFRGAQAQIWSQSCSFITSASLKCAVKLGIPDTIDNHGKPITLSELTNALVPPVHPSKAPFIYRLMRVLAKNGFCSEEQLDGETEPLYSLTPSSRILLKKEPLNLRGIVLTMADPVQLKAWESLSDWYQNEDDSSTAFETAHGKNFWGYSSEHMEHAEFFNEAMASDSQLISKLLIGEYKFLFEGLASLVDIGGGTGTIAKAIAKNFPQLKCTVFDLPHVVANLESKENVEFVAGDMFEKIPSANAIFLKWILHDWNDEDCVKILKSCKKAIPAKGGKVIIIDMVMYSDKKDDHLVKTQTSMDMAMLVNFAAKERCEKEWAFLFKEAGFSDYKIYPKLDFTRSLIEVYP
What is the function of this protein?
16-O-methyltransferase involved in the biosynthesis of vindoline.  Highly specific for 16-hydroxytabersonine.  No activity with tabersonine, 3-hydroxytyramine, 4-hydroxytyramine, 5-hydroxytryptamine (5HT), 2,3-dihydro-3-hydroxytabersonine, lochnericine, hoerhammericine, 16-hydroxy-2,3-dihydro-3-hydroxytabersonine, 16-hydroxylochnericine, 16-hydroxyhoerhammericine, quercetin, kaempferol and caffeic acid as substrates.
What are the official names of this protein?
Tabersonine 16-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.