PharMolix/UniProtQA huggingface dataset:
Protein: SZRD1_XENLA
Sequence: MEEDEVAESWEEAADSGEIERRLEKKLKISQRENNNTKSPPRAPVVIQDDSLPSGPPPQIRILKRPTSNGLASSPHACSRPAAPVKSLAQREAEYAEARKRILGSASPEEEQEKPVAERPARINQVEEIRQQNNVIRQPLGPDGSQGFRQGR
What are the official names of this protein?
SUZ domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SZRD1 family.
Protein: IFNK_HUMAN
Sequence: MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
What is the function of this protein?
May play a role in the regulation of immune cell function.  Cytokine that imparts cellular protection against viral infection in a species-specific manner.  Activates the interferon-stimulated response element signaling pathway.  It is able to directly modulate cytokine release from monocytes and dendritic cells.  Binds heparin.
What are the official names of this protein?
Interferon kappa, IFN-kappa.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_HELAH
Sequence: MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIERAIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQVQKITDEAIKKIDESVKNKEDAILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_ACISJ
Sequence: MAEIKNYSLNFGPQHPAAHGVLRLVLELDGEVVQRADPHIGLLHRATEKLAEHKTYIQSLPYMDRLDYVSMMCNEQAYCLAIEKMLGIEVPLRAKYIRTMFGEITRLLNHLMWLGSHGNDCGSSTILIYTFREREDLFDMYEAVSGARMHAAYFRPGGVYRDLPDSMAQYKVSKIKNAKAIEELNRNRQGSLLDFIDDFTQRFPKCVDEYETLLTDNRIWKQRTVGIGVVPAERALNLGMTGPMLRGSGIAWDLRKKQPYDAYDRVDFDVPVGVTGDSYDRYLVRVQEMRESNRIIKQCVDWLRANPGPVITDNHKIAPPSREAMKSNMEELIHHFKLFTEGFRVPAGEAYAAVEHPKGEFGIYMVSDGANKPYRLKIRAPGFAHLATLDEMARGHMLADAVAIIGTMDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SAE2A_XENLA
Sequence: MAVIGALPKEVAEAVSASRLLVVGAGGIGCELLKNLVLTGFTNLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDANITAYHDSIMNPDYNVEFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTKAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRKRKPPIPLEWASLHNKENCSEIQNESSLLGLKDQKVLNVASYAQLFSKSVETLREQLREKGDGAELVWDKDDVPAMDFVTAAANLRMHIFSMNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEKFAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEFGIRNSSQLQADDFLQDYTLMMNILHSDEMEKDVDFEVVGDVPEKGPQKPPEESVKNITNGSDDGAQPSTSKAQDQDDVLIVDSDEESPSSSNADVGMESASLKRKLPDEEAVSSTKRKRIEPPVEEDDDIIALD
What is the function of this protein?
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3.  It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 2-A, Ubiquitin-like 1-activating enzyme E1B-A, Ubiquitin-like modifier-activating enzyme 2-A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_STAA9
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_VIBPA
Sequence: MTKHVEIFTDGSCLGNPGPGGYGIVLRYKDVEKTLSKGYTLTTNNRMEMLAAVVALQTLKEPCRVTLTTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNADLWQALDKETARHQVDWHWVKGHAGHRENEICDELARTAAENPTEEDTGYQPS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HI, RNase HI.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX8B_XENLA
Sequence: MEPLSPYPLKCSSPKAKVFLVFFSMVLCTGILCVLQLKFLRAKGGDFYSYEVTDAKGRTVALSKYRGKASLVVNVASGCPHTEANYRSLQELHREFGPSHFTVLAFPCNQFGESEPGTNKEIEAMAKRNYGVTFPVFSKIKILGSEAEPAYRFLVDSTKKEPRWNFWKYLVDPQGQVVKYWRPDETAESIRPEVASLVRQIIMKKKEDL
What are the official names of this protein?
Probable glutathione peroxidase 8-B, GPx-8-B, GSHPx-8-B.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRPF_SACK1
Sequence: MSFVNIRSSRGPVVKVCGLQSLKAAQCALDSDADLLGIICVPGRERTVDPVVAMEISALVRACRTSMSTPKYLVGVFRNQSKEDVLRIANDYGIDIVQLHGDEPWQEYQKFLGLPVIKRLVFPRDCDILLSTPSEKTHLFMPLFDSEAGGTGELLDWNSISDWFAEQGNPECLQFMLAGGLTPENVSDALQLHGVIGVDVSGGVETNGMKDMDKITNFVRNAKKES
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TPC6A_MOUSE
Sequence: MADAVLFEFLHTEMVAELWAPDPDPGSGGKRRSLSVLEGLGFRVGQALGERLPLETPAFREELDALKFLCRDLWAAMFQKHMDGLRTNHQGTYVLQDNSFPLLVTMGSGPQYLEEAPKFLAFTCGLLCGALHTLGFQSLVTASVASLPACKFQVVIQKS
What is the function of this protein?
May play a role in vesicular transport during the biogenesis of melanosomes.
What are the official names of this protein?
Trafficking protein particle complex subunit 6A, TRAPP complex subunit 6A.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: SECA_HAES1
Sequence: MLRTIVTKIFGSRNDRILRRLNKQVRIINKLEAEFELLTDEELKSKTTEFRTRLKNGEKLENLIPEAFATVREASKRILGMRPFDVQLIGGMVLNNRCIAEMRTGEGKTLTATLPCYLNALTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGINVPGLSPEEKRAAYAADITYATNSELGFDYLRDNLAHSAQDRFQKHLHYALVDEVDSILIDEARTPLIISGPAEDSSELYMAMDKLIPILIQQDKEDTEEYQGDGDFTLDLKNKQAHLTERGQEKIEQWLMEKGFINENESLYSPARISLLHHIYAALRAHKLFERDVDYIVKNGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVQIQGENQTVASITYQNYFRLYEKLAGMTGTADTEAFEFQQIYGLETIVIPTNKPMIRDDRTDIMFENEKYKFDAIIEDIKDCVARNQPVLVGTISIEKSELLSNALNKAGIKHNVLNAKFHAQEAEIIANAGYPSAVTIATNMAGRGTDIVLGGNWKAEVAKLDDPTEEQIEEIKAAWQIRHDTVKQAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLTEGKLNFMRKMFTEKGEGMESKMLAKVIAQAQAKVEAHNFDGRKNLLEFDDVANDQRHAIYEQRNALLDNEDIADTIQVIRQDVFNHVIDEYVPPHSLEEQWDIPALETRLKQDFALDLPLSKWLEEDNTFNEDVLRERVLTVAISEYKRKEELVGQETMRNFEKGVMLQTLDELWKEHLSAMDHLRRGIHLRGYAQKDPKQEYKKESFQMFTDMLDTLKLSVITTLSRVQIRTQDEVEKAEQARQKIAERENAAMQYQNNEGTSSLHEKSEHKIGRNESCPCGSGKKYKHCHGSKAKY
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: AROC_LACPL
Sequence: MINYVTAGESHGPQLTGVLTGIPAGLQLDIDAINTGLAARQGGFGRGNRQQIEHDTVQIIGGVRHGVTLGSPIALTIMNRDHAHWAAIMDPVSPATATNTLRQVTRPRPGHADLVGGMKYGHRDLRNVLERSSARETAMRVAIGQICKQLLAQLDIHLVGYVQQIGPKQVTADLTLSVDQLQAQIAQNDLRLPDAALVPEIHELITATKKAGDTLGGVIRVVAENVPAGLGSYTNWDTKLDGQLAAAVMGVNAMKGVEIGDGFAAASHYGSQVMDEISWDEHAGWSRLTNHLGGFEGGMTNGMPIVVKAAMKPIPTLYKPLQSVDIATKVSQKASVERSDTTAIVPASIVVESVVAIELTRALTATFDGSNLARLQQTVTAYREELRQY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: THIME_SYMTH
Sequence: MSTLPERVRERRPLVHAITNCVTMEWVARGLLAAGARPVMARDAAEAPVVAAAADALVLNLGTWSPGLQQAMLEAGQVAARRGIPVVLDPVGAGGTETRTRAALELLERVRVTAVRGNAGEILALAGRDGLVRGVDGPDGRPGPQTERAARAVARRFGCLVAVTGATDLVTDGRRTLAVRAGHPLMSQVPGTGCLATALVAAALAAGTGAGPAGRDRPMEDVDVVAEALLWAGWAGEQAASAASGPGTFAAAFLDRLALRGPLPPGRIAPPLSERLSLYVLVSGATPPDVLEAVLQAGCRMIQFREKRLPLPAQLEAAARVREACRRHGALLVVNDRVDLALAVGADGVHLGQEDLPVAAARRILGPDAVIGATCETAGEARAARDAGADYIGAGPVYVTPSKPDAGEPYGPDVVRRVSEAADLPVVGIGGIGPGRAAPVIAAGAAGVAVISAVLGAPDPGAAARAILDEVRRAKGEVSA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine biosynthesis bifunctional protein ThiM/ThiE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thiamine-phosphate synthase family.
Protein: ASSY_YERPB
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROBG_OLEEU
Sequence: MLWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKETGQALVCGIYKEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PH1_PRUSE
Sequence: TYPPVVXATLXRTH
What are the official names of this protein?
Prunasin beta-glucosidase 1, Prunasin beta-glucosidase I, Prunasin hydrolase isozyme I, PH I.
Protein: SCAF4_HUMAN
Sequence: MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR
What is the function of this protein?
Anti-terminator protein required to prevent early mRNA termination during transcription (PubMed:31104839).  Together with SCAF8, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins (PubMed:31104839).  Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation (PubMed:31104839).  Independently of SCAF8, also acts as a suppressor of transcriptional readthrough (PubMed:31104839).
What are the official names of this protein?
SR-related and CTD-associated factor 4, CTD-binding SR-like protein RA4, Splicing factor, arginine/serine-rich 15.
Protein: RPOA_ACTP2
Sequence: MQGSVTEFLKPHLVNIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEVLLNLKGLAVKVSGKDDIILTLNKSGIGPVTAADITHDGDVEIVNPHHVICHLTDKDASISMRIRVQRGRGYVPASARVHSQDEDRPIGRLLVDARFSPVDRIAYNVESARVEQRTDLDKLIIEMETNGTIDPEEAIRRAATILAEQLDAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSHNCLKAETIHYICDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HSLU_STAAM
Sequence: MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTELGYVGRDVESMVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGGAIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTNQNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGIIFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RELB1_METJA
Sequence: MLNINKEIAQIETELNELKKLRDEISERIEKLEIKLLKLKALAIPEEEFEEDYEEIIEDVKKSLDKKETVPAEEALKELGLL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is RelE1 (Potential).
What are the official names of this protein?
Putative antitoxin RelB1.
Protein: CYAY_PSYIN
Sequence: MNDSEFIQLADQLYQKIEEKIEESGADVDYDQNGSLLTLEFENHTKLIINRQQPLHQVWLATLENGHHYDYNNGKWIDDRSGDEFLTFLSAAIFKQSKETVDFTE
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ALB1_CANAL
Sequence: MAGRNAINKPKIKLHAQSHAKSLGRKRAARRTTATRSSTSRYAAKGTTAPRPTDSKAVALYTGNAPQPTSTMTTQTLSNKRAKKIARNQRYLAANKLKENETAMEVDNTSEQEKQTKLDQIKKALWSVIENHQKNGYSVVSDPEGTTLGIQSF
What is the function of this protein?
Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein ALB1.
What is the protein family that this protein belongs to?
Belongs to the ALB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: S35E1_RAT
Sequence: MAAAAAAGPGAGAGIPGASGGGGAREGARVAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILALCAGLPPLLRAWRVPPAPPVSGPGPSPHPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVYLSLVPIISGVLLATVTELSFDVWGLVSALAATLCFSLQNIFSKKVLRDSRIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLVVSGFCNFAQNVIAFSILNLISPLSYSVANATKRIMVIAVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARRHLLPVSTSDLSNREHLRSPMEKPHNGALFPQQGDFQYRNILLTDHFQYSRQGHPNSYALSRHDV
What is the function of this protein?
Putative transporter.
What are the official names of this protein?
Solute carrier family 35 member E1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35E subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HLDE_HYDCU
Sequence: MNMHDFSKTKILVVGDVMLDQYWSGRAGRISPEAPVPVVKVADENVRAGGAANVALNIADLGADVNLMGVIGQDSFGQQLNQVLEQAGVASNWVYSESGTICKLRVLSHHQQLIRMDFENAVPELSAKSLAKLVAEKVADYDVLVISDYAKGALQFVEEMIQAAKSQQVPVLIDPKGNDFSRYAGATLVKPNQGEFELIVGVCADQDDLIEKAKQLIQEINIDALLVTRSEHGMALIEKDAGATILKSRAQEVFDVTGAGDTVIATLATAFGSGLSMPKSVKLANEAASIVVRKVGTSTVSKVELEEQLNASMRHQGYASMSEDEVHSLVQIAQSKGEKVVFTNGCFDLLHSGHVRYLNEAARQGDRLVVAVNSDESVKLLKGDSRPIVELAGRMELLSALSCVDWVVPFNEETPERLICKLAPDVLVKGGDYKPDEIAGAQCVWDKGGEVAVLSFWEGYSTTRMVDKIQEAEIKEGAAQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CH10_PSECP
Sequence: MSVSIKPLEDRIVVRPLEAEQTTASGLLIPDSAQEKPQEGEVVAVGPGRFEDGNRVPVDVAVGDVVIYSKYGGTEVKTGGTEYLVLSARDVLAIVVK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_PECAS
Sequence: MNKPFNCIGIVGHPRHPTALATHEMLYHWLTEKGYSVLIEQQIARELNLKDAPTGSLADIGQQADLAVVVGGDGNMLGAARVLSRYDIKVIGVNRGNLGFLTDLDPDHAQQQLSDVLDGHYLSEQRFMLEAHVCRTNQPDSISTAINEVVLHPGKVAHMIEFEVYIDDRFAFSQRSDGLIIATPTGSTAYSLSAGGPILTPSLEAIALVPMFPHTLSARPLVINSSSTIRLKFSCITNDLEISCDSQIALPVQEGEEVLIRRSEHHLNLIHPKNYSYFNTLSSKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_LEGPC
Sequence: MFRDVLKTLPQYLIPKHGITALAGYFADVKSPRLKNFLIRNFIRKFDVDMSEALIEDPKSYDCFNDFFIRHLKPECRPLSQSDVICPVDGCISEIGKIERGQLLQAKGKYYSVQELLACDGQLAEQFVQGQFATLYLSPKDYHRVHMPIDAELVSMTYIPGALFSVQPATTRVVPKLFARNERLAIFFKTKIGPMVMVMVGATIVGAIGTSWHGDVKRAKKLERFDYSERFPDKIISQGSEMGYFKLGSTVVLLFANGEKIQWDKELLAGSKIQLGKPMAIIT
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNH_ECOSM
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_TRIV2
Sequence: MLTLKIAVYIVVAFFVAIFVFGFLSNDPARNPGRRDLE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.