PharMolix/UniProtQA huggingface dataset:
Protein: CYTB_SHEEP
Sequence: MMCGAPSATQPATAETQAIADKVKSQLEEKENKKFPVFKALEFKSQLVAGKNYFIKVQVDEDDFVHIRVFESLPHENKPVALTSYQTNKGRHDELTYF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-B, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I69A0
Sequence: MSLLTEVETPIRNEWGCRCNDSSNPLVVAASIIGILHLILWILDRLFFKCITRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDGHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RL17_CHLCV
Sequence: MQHARKKFRVGRTSAHNRCMLANMLKSLIHQERIETTLPKAKELRRCADKMITLAKKNTLAARRLAVARLMVRYNKLTSKEARQAKAGDLSAYNVDRTVINKLFDQLGTRFVSRNGGYTRILKLQNRVGDNARKCIIEFLAD
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL5_HALHL
Sequence: MATLRKVYREEVTPALKERFGYQNVMQVPQLQKIVINMGLGEATKDKKILEAAQEDLAKIAGQKPVVTRARKSVAGFKIREGWPIGCKVTLRRDRMYEFLERFIHVASPRVRDFRGFSPRSFDGRGNYNLGIREQLIFPEIDYDEIDRVRGMDITVSTTARTDAEGKALLEGFGFPFRT
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GLPE_ECO45
Sequence: MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHATQAFHLTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_ECOL6
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVASILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ACIF5
Sequence: MLASRVIPCLDIDHGRVVKGVQFVALRDAGDPVEVAKRYNDEGADEITFLDISASYEERGTLADMVSAVAAQVFIPLTVGGGVRCVEDIRTLLLAGADKVSINSAAVNDPELVRAAARRFGNSCIVVAIDAKRVEDHWEVFTHGGRRGTGLDAVAWAQRMAAYGAGEILLTSMDRDGTGIGFDLALTRAISDAVPVPVIASGGVGEIRHFVEGIQQGRADAVLAASVFHFGQFRISEVKARMAAAGIPVRTTR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_TREPS
Sequence: MKHSITGTIGDHPLLLESGYLARQANGSVYLQCEGTAILATVCSSAQRQEGLDYVPLTVDFNEKYYAVGKMPGGFIKREGRPKDREILISRLIDRPMRPLFEKEFGRDIHVVPTCISSDMVHPHDVLAIVASSAAVTLSDIPFHGPVAAVRVAYLNGSYVINPTFSQIDAASMEVVVAGTRQGITMVEGGAREVSEDLMLGALEQAQEHIKALCDMQERLRGLCGKEKQTVIPSSAQLVGRDRIYELAYPRLAQALYAQGKGERRSACDAVKRDVAQQYAAQLENDVQRRLFDALFHEMEYEILRLNILDRGLRIDGRAIDAIRPIACEVGVLPRPHGSAVFTRGETQSLAVVTLGAMSDGQVYDDIEGDRRENFILHYNFPPFSVGEIGRMGVGRREIGHGCLAHRSLSAVIPDPEQFPYTVRVVSEILESNGSSSMATVCSGTLSLLHAGVPIKKPVAGIAMGLITDGVRYAILSDILGEEDHLGDMDFKVAGTCDGITGFQMDVKVEAVSASLMKEALQQARVGRLHILSVMNQTISAPSVHISRYAPHIESFKIAVEKIGALIGPGGKTVKSLSDQYRVTINTDSDGTVTVSGRDAQSVFDAKVAVVGLTEDPRVGRVYQGVVKRIVEFGAFVEIFPGKEGLCHVSKLSRSRVSKVSDVLQEGQRICVKLIDIDRMGRLNLSYIDALEGKSGGLDTTK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_THEMA
Sequence: MLEFSSEVSLLDSVKNILLEYGLRFQEPQIEKVDKYIEELLGVPYNLTAHRDLDSAVHKNVVEILLPLKEELKGTLLDVGSGNGVPGLILAIFFSKLKVVLLDSREKSVNFLRGVIEKLDLENVSVVKERAENFSKERREEFDYVTARAVARLNVLVEICTPALKTGGKLLFYKGPSYIEELKEAQRAMKELKVELEKVREYSLKTGERRALLILRKYESSPEKYPRRVGVPFKRPLL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_SHESW
Sequence: MKSLSFLNHEFEAFPSPELALTDPNGLLAIGGDLRPERLLTAYYNGIFPWFNADDPILWWSPDPRAIFMLGKIRISTSLCKYLKKQPWHFTINHAFTSVMAGCAEPRPKQNGTWITDEIQMAYRELHQNGHAHSIEVWEGEQLIGGLYGLAIGQVFCGESMFHRQTNASKAAIVVLQQHLIKRGFKLIDAQVMNPHLESLGAKAIKRTHFIELLTQFRDKKVHPDAWIPSEVFLEL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRSK1_HUMAN
Sequence: MSSGAKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRRGPPKDKKLLATNGTPLP
What is the function of this protein?
Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication.  Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1.  Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'.  Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons.  In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.  Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome.  Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C.
What are the official names of this protein?
Serine/threonine-protein kinase BRSK1, Brain-selective kinase 1, Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Synapses of Amphids Defective homolog 1, SAD1 homolog, hSAD1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Synapse. Presynaptic active zone. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage (By similarity).
Protein: MSRB9_ARATH
Sequence: MPTSATAVAPSTGSVQKKDQDWRAILSPEQFRVLREKGTENRGKGEYTKLFDDGIYSCAGCATPLYKSTTKFDSGCGWPSFFDAIPGAIKQTPEAGGRRMEITCAACDGHLGHVVKGEGFPTATDERHCVNSVSLKFSEISSQ
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRB family specifically reduces the MetSO R-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase B9, AtMSRB9, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ATI_CAMPC
Sequence: MELTNLIEKCTKLSKDFATEVEKLWNDELSSESGLSRKTRNVIRNILRDITKSLTTDKKSKCFCILERSTINGEQIKDVYKTIFNNGVDVESRINTTGKYVLFTVMTYAAAELRLIKSDEIFALLSRFFNMICDIHRKYGCGNMFVGIPAALIVLLEIDHINKLFSVFSTRYDAKAYLYTEYFLFLNINHYLLSGSDLFINVAYCAVSFSSPIRVPDYIMEALTFKACDHIMKSGDLKYTYAFTKKVKDLFNTKSDSIYQYVRLHEMSYDGVSEDTDDDDEVFAILNLSIDSSVDRYRNRVLLLTPEVASLRKEYSEAEPDYKYLMDEEVSAYDKHLPKPITNTGIEEPHATGGDKEDQPIKVVYPPNNDKDDAIKPHNPLEDPNYVPTITRTDIGIADYQLVINKLIEWLDKCEEECGNGGEFKTELEEAKRKLTELNAELSDKLSKIMSLERDSVHKTERIDRLTKEIKELRDIQNGTDDGSDSSEIDKKIIRELRESLDREREMRSKLEKELDTIRDGKVEGSCQRELELRRMWLKQRDDDLRAEIDKRRNVEWELSRLRRDIKECDKYKEDLDKAKATISNYVSRISTLESEIAKYQQDRDTLSVVRRELEEERRRVKDLESRLDECTRNQEDTQEVDALRSRIRELENKLTDCIESGGGNLTEISRLQSRISDLERQLNECRGNVTEISRLESRISDLERQLNDCRRNNETNAETERDATS
What is the function of this protein?
Structural protein that forms a matrix surrounding the mature virion (MV) through interaction with protein A26.  Presence of protein A25 in the virion structurally prevents direct virus-cell fusion mechanism (By similarity).
What are the official names of this protein?
A-type inclusion protein A25 homolog, ATI.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A25 protein family.
What are the subcellular locations of this protein?
Virion. Note=Present above the membrane of mature virions (MV).
Protein: RL3_XANOR
Sequence: MTKKYSLGFVGRKAGMSRIFTEDGRSVPVTLIEATPNRIAQIKTVEVDGYSAVQITVGARRAALVNKPAAGHFAKAKVEAGRGLWEFRVEDAHLGDFAVGGEIKADIFEVGQKVDVQGVTKGKGFQGTIKRYNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVQQSTQNLEVVKVDVERGLIAIHGAVPGAAGGDVIVRPASKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y5053_ARATH
Sequence: MANQGGPSRKSLSFSGHSFQGRKKASENEGGGGGGSDLLPRRSLTSSRSSISLSGERSGERTVKRLRLCKALTVPDSTTLFEACRRMAARRVDALLLTDSNALLCGILTDRDIATKVIAKQLNLEETPVSKVMTKNPVFVLSDTIAVEALQKMVQGKFRHLPVVENGEVIALLDIAKCLYDAIARMERSVEKGKAIAAAVEGVEKNWGTSIAGPNTFMETLRERIFKPSLSTIIPENTKVLKVGLDETVLGVTMKMVEYQSSAAMVMVENKLVGILTSKDILMRVISQNLPQETTTVEKVMTPNPESATVDMAIVEALHIMHNGKFLHLPVLDKDGDVVAVIDVIHITHAAVTTAGSTAGINNETANSMMQKFWDSAMALSPNEDGDETRSEEESMKLSSEIEVTKSFSYPNTFAFKLQDKKGRMHRFMCETQSLTTLITAILQRMGDDIEPDNLPQIMYEDEDNDKVVLASDNDLGAAVEHAKSIGWKGLKLHLDYTEERGHRRGLSSEDMDYDQSNSWAAAYKTVAAGAALAAGLGVLVYLKRNSN
What are the official names of this protein?
CBS domain-containing protein CBSCBSPB4.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TIG_CAMHC
Sequence: MEISAKLTNSANALASTKIPTASINEKVNELAKQTAKKVRIDGFRPGKAPVAAVLKRYKKELEDDAKNDIFRNFVDESLKILGKEKNEILGEPIFSKYEEKDGIIDVEMKMSFRPEVKIDGYEKFIPEFATPRVTKKEIDEKINEFLLMIAPLEKSDKEVLEKGDFAKFDFEGFVDDKPFDGGKAQDYVLEIGSGRFIPGFEDGMLGMKIDEERDIKVKFPENYQAENLAGKDAIFKVKLHEIQCKKIGELDDETLKRLMPGEKEPSKEKFEAQIKEQIRADKMAKLINEELKPKFADIIVENFIFDMPEIILEQEIDLQFRNAWGTFSKEEIENFRKDKDALTKKRDEFRDEAVKSVKMTFLIDEIAKDRKIQVSDQELVSAVYMEAYRYGMDPKKHLEEYRTNGYLPVVKMALLEEKLFNDIFSKDKKSEKTEEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PRGR_NOTEU
Sequence: KNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVAVPQPVGLPNESQALTQRITFSPNQEIQLFPPLINLLLSIEPDVIYAGYDNTKPETSSSLLTSLNHLAERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYS
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: PYRE_CHLPD
Sequence: MNQPPMLDIFRSTGALLEGHFKLTSGRHSNTYFQCAKVLQHPEHLSAVCHKIAAHFSQKGVDTVISPAIGGIVAGTETGRQLGVKTIFAERKDGRMTIRRGFSVAPGEKVLVIEDVITTGGSVQEVIELLKNAGALIIGVGCVVDRSNGKVRLTDDQYAVLSMEVVSYAPEECPLCKEGMPIDAPGSRANQQP
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: DAPB_BARBK
Sequence: MRLVVVGANGRMGRELITACQNREDIELSGVLVREKSPFVGQDVSILIGSAPLGIRITDDPENAFSNADGIVDFSQPQASVIHADYAAQKGLVHIIGTTGFSKEEDAQIAISATRTTIVKSENMSLGVNLLANFVKKAAKALGAHDFDIEICEMHHSKKVDAPSGTALLLGNAAAEGRHVALKEVSASGRNGYTGERKKGTIGFACLRGGTVIGDHSVIFAGLNERITFSHSAQERSIFAHGALKAALWAKNYKNGLYSMLDVLELNN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_PARD8
Sequence: MSAEKKKELQVAALENGTAIDHIPPSQLFKVASLLGLEKMNNTITIGNNFHSNKMGCKGMIKIADKFFEEDEINRIAMIAPNIILNIIRDYEVVEKKTVTLPDELIGLVKCNNPKCITNNEPMLSRFHVIDKEKGTIKCHYCERKINKEDIIIK
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RISB_VESOH
Sequence: MEFKFNKDGSRDFLSKKKIAIIVGYFYQDICDNLLLASQETLTKYGIKANNINVFYAPGAFEIPLLAKKLASQQINGKNLYNGIVALGAVINGETPHFKFICNECARGVSNVSYQYEIPTTFGVITTNNMEQTIARAGGYKGNKGEEATMAMIIMLYLMQQADTQFF
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: EFG_RICPA
Sequence: MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVEMLKDRLGAKPLVIQLPVGIEENFKGIIDLIKMKAVIWKDEALGAEYFEEDIPADMKDKAEEYRAKLLDMVVELDDHVMEKYLSGEEVTAEEIKRLIRKGTISAVFYPVLCGSAFKNKGVQPLLDAVVDFLPSPIDIGIVKGREVSTGEEKDFLISVTEPFAALAFKIMNDPFVGSLTFIRIYSGKITSGTTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDIDQQVILERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFRVSTDYETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKVCEIDYTHKKQSGGAGQFARVKIIFEPLKEVKDLKDEDKNKIFVFESKIIGGAVPKEYIPGVEKGLNNIRETGVIAVYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMQVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTANVPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMN1_HUMAN
Sequence: MEGTHCTLQLHKPITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDIISLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQELSVSLAPEDDCFQSAGDWQGELPVGPLNKRSTHGNKKPRRSSGRRESFGALPQKRTKRKGRGGRESAPLMGKDKICSSHSLPLSRTRPNLWVLEEKGNLLPNGALACSLQRRESCPPDIPKTPDTDLGFGSFETAFKDTGLGREVLPPDCSSTEAGGDGIRRPPSGLEHQQTGLSESHQDPEKHPEAEKDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKETIAIRPAAHAEFVPKADLLTLPGAEAGAHGSRRQGKERQGDRSSQSPAGETASISSVSASAEGAVNKVPLKVIESEKLDEAPEGKRLGFPVHTSVPHTRPETRNKRRAGLPLGGHKSLFLDLPHKVGPDSSQPRGDKKKPSPPAPAALGKVFNNSASQSSTHKQTSPVPSPLSPRLPSPQQHHRILRLPALPGEREAALNDSPCRKSRVFSGCVSADTLEPPSSAKVTETKGASPAFLRAGQPRLVPGETLEKSLGPGKTTAEPQHQSPPGISSEGFPWDGFNEQTPKDLPNRDGGAWVLGYRAGPACPFLLHEEREKSNRSELYLDLHPDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKEASVTTN
What is the function of this protein?
Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
What are the official names of this protein?
Formin-1, Limb deformity protein homolog.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Cappuccino subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localization to the adherens junctions is alpha-catenin-dependent. Also localizes to F-actin bundles originating from adherens junctions and to microtubules (By similarity).
Protein: ARLY_SALA4
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGRLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKETVRELLTANRQLQSALVETAQANQDAIMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAIDDAKARLAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHIT_AZOBR
Sequence: MAKTYDPNNVFARILRGEIPCKKVLETEHALAFHDINPQAPTHILVIPKGAYVDMDDFSARATEAEIAGLFRAVGEVARGAGAAEPGYRILSNCGEDANQEVPHLHIHVFAGRRLGPMITKG
What are the official names of this protein?
Uncharacterized 13.2 kDa HIT-like protein in hisE 3'region, ORF2.
Protein: A47_VACCC
Sequence: MGNKNIKPSKENRLSILSKDKMDSFKRGSWATSSFREKSRATIQRFSSLRREHIKVDHPDKFLELKRGIYEIIQKSSSIDVDKRTKLMSNIKTMMINPFMIEGLMTSLENLDPDNKMSYSSVMILGEFDIINISDNEAAFEFINSLLKSLLLLNTRQLKLLEYSISNDLLYAHINALEYIIKNTFNVPERQLILRGQYLTPIFSDLLKYAGLTIKSNILMWNKQFIKPVSDLYTSIRLLYCVTV
What are the official names of this protein?
Protein A47.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus A47 protein family.