PharMolix/UniProtQA huggingface dataset:
Protein: RS6_EHRRG
Sequence: MPLYEFTFIAQQGLTQYELEGLVKGLSSLLTKNGAELLKYEYWGLLDFAYAIDKMNKGHYCMMYIRSSSTSMDEFKRKVRLNEDVLRFLCLKRDKLPEGDSLMVQASQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DAPB_STRT2
Sequence: MSIKVIVAGFKGRMGSTAVEMVKGDDELTLAALLDPFAAEKEVDGVPVFTDKADLVGFDADVWVDFTIPAVAYENTRFALENGFAPVVGTTGFTEAQIQKLTDLSKDKSIGGLIAPNFAIGAILLMKFAAEASKYFPDLEIIELHHDKKKDAPSGTAVKTAELIREVRESKRQGAEDEMETLAGARGAEFDGFRIHSVRLPGLVAHQEVIFGAQGEGLTLRHDSYDRISFMSGVNLGIKEVVKRDQLVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_BACC1
Sequence: MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAKIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLQERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DPO3A_STAEQ
Sequence: MVAHLNIHTSFDLLDSSLRIDALIDKAKKEGYRALAITDTNVLYGYPKFYDACIAAHIHPIFGMTIYLTDGLYTIETVVLAKNNQGLKSLYQLSSAIMMRNKEEVPIEWLKRYDEHLIIIFKEAELSHKQVIDAFEGKKELYLNHNSNNTLTGKRVWMQSARYLNEDDAETIPALHAIRDNTKLDLIHEKETLDEHFPSIEELQTLNLSEDMITNANEIEELCQAEIAYHQSLLPQFVTPNGETSKDYLWTILIHRLREWELNDKTYFNRLKHEYKIITDMGFEDYFLIVSDLIHFAKTHEVMVGPGRGSSAGSLVSYLLGITTIDPLKYNLLFERFLNPERVTMPDIDIDFEDTRREKVIKYVQDKYGEHHVSGIVTFGHLLARAVARDVGRIMGFDETSLNEISKLIPHKLGITLEEAYQKPEFKAFVHRNHRNERWFEVSKKLEGLPRHTSTHAAGIIINDQPLFKFAPLTTGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQIILQVKKDLNINIDIEAIPYDDKKVFDLLSNGDTTGIFQLESDGVRSVLKRLQPEHFEDIVAVTSLYRPGPMEEISTYITRRHNPNQVAYLHPDLEPILKNTYGVIIYQEQIMLIASQVAGFSYGEADILRRAMSKKNRAILESERQHFIDGAKNNGYDEQISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSYLKVHYPHYFYANILSNVIGSEKKTAAMIDEAKHQRISILPPNINQSHWYYKASNKGIYLSLGTIKGIGYQSVKLIIDERQQNGPYRDFFDFSRRIPKRVKNRKLLESLILVGAFDTFGKTRATLLQAIDQVLDLNSDVEQDEMLFDLLTPKQSYEEKEELPDQLLSDYEKEYLGFYISKHPVEKKFEKKQYLGIFQLSNGSHYQPILVQFDHIKQIRTKNGQNMAFVTMNDGRTMMDGVIFPDKFKKYETSISKEQMYIVLGKFEKRNQQMQLIINQLFEVEAYEQTKLSNSKKVILRNVTHLEPQFEHSKVESNEQHALNIYGFDESANKMTMLGQIERQRQNFDLLIQTYSPADIRFI
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADIG_BOVIN
Sequence: MKYPLVPLVNELTFSFLVFWLCLPVALLLFLLIIWLRFLLSQDSEENDSDVCLDWEPWSKNPDEFCQEEMLHSQEEERPCC
What is the function of this protein?
Plays a role in stimulating adipocyte differentiation and development.
What are the official names of this protein?
Adipogenin.
What is the protein family that this protein belongs to?
Belongs to the adipogenin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus.
Protein: PTAC6_ARATH
Sequence: MASSAASPSLSLLSFTSKPPYPSGSQRLFASFRTDGLFAPLTLKSRRGRGIVVKVDDVDADGGGADEYDMDDEEVEEVDNKKDYDVEYDPLAAAIAAAGGGGDGDIAFVQSKSFISTQGWDSDMVVDYRINEDEFHKLSLMDCDFFIRKPPDPDNDVYDFREMYVTPPDTDIYSIPRVLAPMPQKYIRCAMSDYGCYNVTEPPIDAPRDPLYKSEREISKVFLTKHYRNRRTNDPEFVLDLEEIYVIDSKTKSITRARVLVTVPGGRKRDRKDDLLVIRDNGTSFKIIHVGERDDPTTVIEREEWTKTREDMEKHLRKLRDFSVSNWF
What is the function of this protein?
Essential protein involved in plastid gene expression (PubMed:16326926, PubMed:31128276).  Recruited by MTERF5 to the transcriptionally paused region of psbEFLJ (PubMed:31128276).  Promotes leaf greening (PubMed:24272250).
What are the official names of this protein?
PLASTID TRANSCRIPTIONALLY ACTIVE protein 6, chloroplastic, pTAC6.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNME_CHLPD
Sequence: MQQETGIHPIVQCDPIAAIATPLGVGALAVVRISGATAFDIAGRVFRKARDPHQPLSETPGYTAHFGRLYDGLTLIDEVIALVFRSPSSFTAEDMVEFTCHGGPVVTRHVLQLLLDNGCRLAEPGEFTRRAFLNGKIDLLQAEAIGEMIHARSESAYRTAVIQMKGDLSATLGALREKLLRSCALLELELDFSEEDVEFQSREELRVEIASLQSEVARLVDSYQHGRLLTEGVATVIAGRPNAGKSTLLNTLLGEERAIVSHMPGTTRDYIEECFIHDKTMFRLTDTAGLRETGEEIEHEGVRRSRMKMAEADLLLYLLDLSREGMAEEIKEIVALKAAHASSKFLVVANKIDLVPDATTLLCRLGEEAGCEAIGISARQKLGIDELKSRMSSMVEGLDKLHEASVLVTSLRHYEALRNAGDALRNAQNLLDEQADTELIAFELRAALDYVGEITGKVVNEEILHAIFERFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ASHGO
Sequence: MAPAKNQENINQKLALVIKSGKYTLGYKSTIKSLRQGKAKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVTVLDAGDSDILTTLA
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: ECTC_VIBCH
Sequence: MIVRTLEECRQSERRVVAENWESVRMLLKDDHMGFSFHITTIYANTQTHIHYRNHLESVYCMSGEGEIEVVGGKTYPIQPGTLYILDQHDEHYLRAFSSEMVMACVFNPPLTGHEIHDAEGVYPLDKSELISQCHKEK
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: GPDA_NITOC
Sequence: MALPVALQNDKENLRTLVVGGGSWGTALAILLARNRVPTLLWARDLAQVSAMIITRRNDRYLPQVPFPPSLEPITDLEGALSQTKQVLVAVPSCGFRPILERLAGHLSSHVPLIWATKGLEPGTGRLLHEVVLELLGSGWPMAVMSGPTFAHEVVAGLPTAVTVAATESEIATCFARSLHGDTFRVYTSDDLIGVQLGGAVKNVLAIAAGISDGLGFGANTRAALITRGLTELVRFALAWGGQRETLMGLSGLGDLVLTCTDDQSRNRRLGLALAQGKRLDEALTLIGQAVEGAAAAKVVVARAKQLAVEMPIAEQVYQVLYAGRHPRQAVEVLCRREQKPEYA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAC_STAAU
Sequence: MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
What is the function of this protein?
One of three proteins encoded by transposon Tn554 required for its transposition.
What are the official names of this protein?
Transposase for transposon Tn554.
Protein: EFTS_ALBFT
Sequence: MAAITASMVAELRGKTDAPMMECKRALTEAQGDMVKAEELLRVKLGSKAGKAAGRITAEGVITSYMEADVGALLEVNCETDFVTKNDSFLALANAAVKLIAQNNPADLAALAALPYTQDGFGPTLEDVRKGLIGKIGENMSFRRFKRFASGAKLASYLHGTRIGVVVEFDGDATAAKDVAMHVAAMKPVALSSDDVPAELVARERSVAAAKAAEDASVATAAGKPVQSAEIVAKRIEGGVQKYLKEVSLFNQSFVKNDKQTVEQMLKATGTTVKAFTLYVVGEGIEKKVEDFAAEVAAQMAAAKQAS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_PYRAB
Sequence: MSGAELIIQEINREAERKIEYILNEAREEAEKIKEEAKRRAESKAEWILRRAKTQAELEKQRIIANARLEVRRKRLAVQEEIIRNVLDEVRKRLQEMPEEEYFESIKALLKEAVEELKEGKVRVYSNERTLALISSRIEEIRDYLGSISIEIGSAISTMGGVIVETEDGRIRIDNTFEARMERFEGEIRAKIAKVLFGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: KCY_ECO45
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_ACIAD
Sequence: MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFNAYVCPSCDEHLRMKARDRLTWFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTGETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFVQAAERAIEQKQALICFAASGGARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKAMIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOD1_CAEEL
Sequence: MTSKRPGGSSFQPEVKRKRESDEFEQCYVSRFENELPSVPTIDKTGWARPAVDKDLGISKSIACQILEVETYHEDGSATSYDRTNVKLYGVTKSGNSICVIVTDYFPHFYFQAPQGFGVEHIGTAQSAICNMVAAAKRRGGSGQAQLPGKVVDNLVHVEIVHGENLYYFRGADTKVPFVKVSGSTEALHKARMELKNGVNLMGKGPVNVGNLYESNINVIVMFLAKTNIVGCGWIEIPAGKCRILSNSEKSSRCQIEVTVPVKNLIVHESDGEWAGIAPIRTLSLDIECIGRRGVFPEAIKDPIIQIANLVKIEGEAEPFVRNCFVLGTCAPVVGSNIIQCVNEKVLLEKWAEFVREVDPDIITGYNILNFDLPYILDRAKVLSLPQVSHLGRQKEKGSVVRDAAISSKQMGSRVNKSIDIHGRIIFDVLQVVLRDYKLRSYTLNSVSYQFLSEQKEDVEHNIIPDLQRGDEQTRRRLAQYCLKDAYLPLRLLDKLMSIINYIEMARVTGVPMNFLLTKGQQIKILSMMLRRCKQNNFFLPVIEANSGDGEGYEGATVIDPIRGFYNEPIATLDFASLYPSIMIAHNLCYTTLLKSPQGVENEDYIRTPSGQYFATKSKRRGLLPEILEDILAARKRAKNDMKNEKDEFKRMVYNGRQLALKISANSVYGFTGATVGKLPCLEISQSVTAFGRKMIDMTKLEVERIYKKGALDGKCPADAKVIYGDTDSVMVKFGVETVAQAMEIGLDAAKEVSKIFTPPIKLEFEKVYSPYLLINKKRYAGLYFTKPDVHDKMDCKGLETVRRDNCPLVAKVLGVCLEKLLIERDQQSALDFAKRTISDLLCNKIDISLLIISKELTKSGDKYQAKQAHVELAARMKKRDAGSAPRLGDRVPYVFVAAAKNVPAYERAEDPTFVLQNNIPLDTKHYLTNQLAKPLARIFEPILGDRAEKILVEGEHTRVRTVVQSKVGGLAAFTTKSATCLGCKSVLPRAESENAVCKHCEPKLPTIFASRMNTMHELENHFGRLWTECQNCAKTMQDKVNCSARDCPIYYMREKVRNELSEASAVIERFGDPCFQAPTK
What is the function of this protein?
Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.  Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis.  Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex (By similarity).
What are the official names of this protein?
DNA polymerase delta catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SOX21_XENLA
Sequence: MSKPLDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRAMHMKDHPDYKYRPRRKPKTLLKKDKFAFPMPYSLTGDHDGLKAVSLHGAGVLTDALLCHPEKAAAAAAAAAARVFFQPSAAAAAAAAAAASGSSTNPYSLFDLSSKMAEMTHSSSSIPYTSSIGYPQSSGGAFAGVTGGGHTHSHPSPGNPGYMIPCNCTGWPSPGLQPPLAYILFPGMGKPQLEPYPAAAYAAAL
What is the function of this protein?
Acts as a negative regulator of transcription (By similarity).  May function as a switch in neuronal development.
What are the official names of this protein?
Transcription factor Sox-21, SRY (sex determining region Y)-box 21.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_SHESM
Sequence: MTTVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNGVHIINLEHTVPMFNEALAFISNVASKKGKVLFVGTKRAAGEAIKEAAISCDQYYVDHRWLGGMLTNWKTVRQSIKRLKELESQSVDGTFDKLTKKEALMRTRELEKLEKSLGGIKNMGGLPDVLFVIGADHEHIAIKEANNLGIPVVAVVDTNSAPDGVNYIVPGNDDAMRAIRLYTTSVAAAANAGRGQDLAVQAEQDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PA2BB_CRODU
Sequence: HLLQFNKMIKFETRKNAVPFYAFYGCYCGWGGQGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKNGYMFYPDSRCRGPSETC
What is the function of this protein?
Monomer CBb: The basic subunit of crotoxin is a snake venom phospholipase A2 (PLA2) that exhibits weak neurotoxicity (10-fold less than the heterodimer) and strong anticoagulant effects by binding to factor Xa (F10) and inhibiting the prothrombinase activity.  In addition, it shows the same effects described for the heterodimer and binds the nucleotide-binding domain (NBD1) of CFTR chloride channels and increases the channel current (PubMed:27241308).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 crotoxin basic subunit CBb, CTX subunit CBb, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: P2C74_ARATH
Sequence: MGSCLSSSGGGGSRRSLHGSPHVPGPGRRKRPPKRRPGSCSSSFDNTEEPLLHRIPGRMFLNGSTDTVSLFSQQGKKGPNQDAMIVWENFGSMEDTVFCGVFDGHGPYGHIVAKRVRDLLPLKLGSHLESYVSPEEVLKEISLNTDDRKISEDLVHISANGESRVYNKDYVKDQDMIQMLIGSIVKAYRFMDKELKMQVDVDCFCSGTTAVTMVKQGQHLVIGNIGDSRAVLGVRNKDNKLVPFQLTEDLKPDVPAEAERIKRCRGRIFALRDEPGVARLWLPNHNSPGLAMARAFGDFCLKDFGLISVPDVSYRRLTEKDEFVVLATDGIWDALTNEEVVKIVAKAPTRSSAGRALVEAAVRNWRWKFPTSKVDDCAVVCLFLDSEPNRLSTASFSKEKHINNGVTEPEPDTASSSTPDSGTGSPELNGVNRIDTLVNLPVYVPTKE
What is the function of this protein?
Acts as a protein phosphatase.
What are the official names of this protein?
Probable protein phosphatase 2C 74, AtPP2C74.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: 3HAO_XANOM
Sequence: MLIPPINLHAWIEEHRHLLKPPVGNKCIQQDGFIIMIVGGPNARTDYHYDEGPEWFFQLEGEMVLKVQDDGVARDIPIRAGEIFLLPPRVPHSPQRAAGSIGIVIERVRLPHEQDGLQWYCPQCNHKLYEAMFPLKNIETDFPPVFDHFYRSLALRTCSQCGHLHPAPERYAAVED
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
Protein: RIB3_MAGO7
Sequence: MPSTDSIPKSNFDAIPDVIQAFKNGEFVVVLDDPSRENEADLIIAAESVTTEQMAFMVRHSSGLICAPLTPERTTALDLPQMVTHNADPRGTAYTVSVDAEHPSTTTGISAHDRALACRMLAAPDAQPSHFRRPGHVFPLRAVAGGVRARRGHTEAGVELCRLAGKRPVAVISEIVDDGQEVEGRAVRAAPGMLRGDECVAFARRWGLKVCTIEDMIAHVEKTEGKLETNGSG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, DS.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: LRRD1_MACFA
Sequence: MSEKEGMSEELEDTISQFRKESRSQSVKEPGFIKETSNLINEASDYLEGKSSNQIYETHPRQITLESTSSSGSKSKRNEEQKKNLQFSETSTRTETSQSLSSLTGRIAEYQALVNFLSHETVGEVSPQVSEENQKHLGLETTCKDNFTVNLEAKGLQEFPKDILKIKYVKHLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKYLRVLNLEYNQLTIFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLLDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELRILILDKNLLKNIPEKICCCAMLECLTLSDNKLTELPKNIHKLNNLRKLHVNRNNMVKITDSISHLNNICSLEFSGNIIAGIPIEIKNCQKIIKIELNYNKIMYFPLGLCALDSLYYLSVNGNYISEIPADISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLRVLDLSENQLQKISSDICNLKRIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYIPPSLLSLNDLQQLNLSGNNLTALPSAIYNLFSLKEINFDDNPLLRPPMEICKGKQLYTIARYLQRADERDEKILEKIFKIVANNITETNFEFLCQKLNLANSETDMPTKSTVSLSERAHQALVIWKTQSNKLSLTAAALRDQLIRALTMIGAYEIMDKITALNLFTRAIKF
What are the official names of this protein?
Leucine-rich repeat and death domain-containing protein 1.
Protein: RL2_PSEPW
Sequence: MAIVKCKPTSPGRRFVVKVVNQELHKGAPHAPLLEKKSKSGGRNNNGRITTRHVGGGHKQHYRLVDFRRNDKDGIPATVERIEYDPNRTAHIALLCYADGERRYIIAPKGVSAGDQLIAGALAPIKAGNSLQLRNIPVGSTIHGIELKPGKGAQIARSAGASAQLIAREGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRGNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SH319_MOUSE
Sequence: MNIMNTEQSQNTIVSRIKAFEGQTNTEIPGLPKKPEIIPRTIPPKPAVSSGKPLVAPKPAANRASGEWDTWAENRLKVTSREGLTPYSSPQEAGITPVTKPELPKKPTPGLTRSVNHETSGGRPMAESPDTGKKIPTPAPRPLLPKKSASTDAPPYPSIPPKLVSAPPRLSVASQAKAFRSLGEGLPSNPPVPAPQSKALGDIDLISFDDDVLPTSGSPAEEPTGSETVLDPFQLPTKTEATKERAVQPAPTRKPTVIRIPAKPGKCLHEEPQSPPPLPAEKPVGNTHSAVSGRPSHSDRTRNPELEQASESGGLVQGPPRLPPRPVHGKVIPVWRPPPKGAPERPPPPKLPASKSSNKNLPFNRSSSDMDLQKKQSHFVSGLSKAKSQIFKNQDPVLPPRPKPGHPLYRKYMLSVPHGIANEDIVSRNPTELSCKRGDVLVILKQAENNYLECQRGEGTGRVHPSQMKIVTPLDERPRGRPNDSGHSQKPVDSGAPHAVALHDFPAEQADDLSLTSGEIVYLLEKIDAEWYRGKCRNQTGVFPANYVKVIVDIPEGRSGKRESFSSHCAKGPRCVARFEYIGDQKDELSFSEGEVIILTEYVNEEWGRGEIRDRSGIFPLNFVELVGDHPTSGANILSTKVPPKTKNEDPGSNSQDSSPPGEWCKALHSFTAETSEDLPFKRGDRILILERLDSDWYRGRLHDREGIFPAVFVQPCPAEAKGVASAIPKGRKVKALYDFLGENEDELSFKAGDVITELEPIDDAWMRGELMGRAGMFPKNYVQFLQVS
What is the function of this protein?
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding.  May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1.  Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).
What are the official names of this protein?
SH3 domain-containing protein 19, Kryn.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_PECCP
Sequence: MAKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFHDWRFLDDAGQQPNPEFVLNKPHYKGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDEEVDELFKLVDGQEGINFIVDLENQVVQAGSKSYPFEIDSFRRHCMINGLDSIGLTLQHEASITEYEKNQPAFLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: WASH1_XENTR
Sequence: MPQNRSMESQAYSLPLILPDLRREEAIHQITDTLQHLQTVSNDIFSRILQRVETNRGQLQRINGRLSLAQAKIERLKGIKKAIKVFSSAKYPAPEHLQEYSSVFAGAEDGWLAKKLRHKIQSKHRPLDEQAVQEKLKYFPVCVNTRGQDEESAEEGLGSLPRNISSVSSLLLFNTTENLYKKYVFLDPLAGVVTRTNPALEGEDEEKLFDAPLSITKREQLERQTAENYFYVPDLGQVPEIDVPYSLPDLPGVADDLMYSADLGPGIAPSAPGVPIPELPTFITEDITENSRTDSQDGRLLPPPPPPPPPPPPPPPPEPSVLSPPTSLAPPLPIPAPARVGSSDVGDPGSLQGAPKEVVNPSDGRASLLESIRQAGGIGKAKLRNVKEKKLEKKKMKEQEQVRATGGGGDLMSDLFNKLAMRRKGISGKGPAAGEASGDGPTGAFARISDTIPPLPPPDQASGDGDEEDWES
What is the function of this protein?
Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
What are the official names of this protein?
WASH complex subunit 1, WAS protein family homolog 1.
What is the protein family that this protein belongs to?
Belongs to the WASH1 family.
What are the subcellular locations of this protein?
Early endosome membrane. Recycling endosome membrane.
Protein: SYL_GEOMG
Sequence: MEEKYIPRNVEEKWQKIWEENKTYKVTEDPSKPKYYLLEMFPYPSGRIHMGHVRNYSIGDVVGRFKRLRGFNVLHPMGWDAFGMPAENAAIQHKSHPAKWTYENIAYMRSQLKKMGLSYDWDRELATCDLDYYKWEQKVFLEMYEKGLAYKKTSYVNWCPKCETVLANEQVEDGACWRCDSEVTQKELEQWFFRITDYAEELLEYTEKLPGWPERVLTMQRNWIGKSYGCEIDFPVEGSLAKIKVFTTRQDTLYGATFMSLAPEHPMALELTTPDRRAEVEAFIDKVKKTDKIKRTAEDFEKEGVFTGSYCINPVTNRRMPVFLANFVLLDYGTGAVMAVPTHDQRDFEFARKYDLPLQVVIQPEGETLDPAAMATAYTEVGTMVNSGTFDGLRSDEAKEKIADYLAKEGIGTKTVNFRLRDWGISRQRYWGNPIPVIYCDICGVVPVPEKDLPVVLPMDVEFTGEGGSPLKKLDSFVNVPCPQCGQMARRETDTMDTFVQSSWYFLRYCCPDFAAGPIDKARAEYWMSVDQYIGGIEHAVLHLLYARFFTKALRDLGYVTVDEPFTNLLTQGMVIKDGAKMSKSKGNVVDPDALINRYGADTARLFSLFAAPPEKDLDWSDQGVDGSYRFLSRVWRLVCDLLPFVGKGGAVDSASLSDDARGLRRAVHKTIRKVTDDIDERFHFNTAIAAIMELVNAIYAFEPKNAPENGPVLTEAIESVVIMLSPFVPHVTEELWEALGHQGGVEAAGWPSFDPSAAVDEEFLIVVQVNGKLRGKVTVATDATEEQVKAAAFADEKVKPWIEGKQLRKAIYVPGKLLNIVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBG8_MOUSE
Sequence: MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCTLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  This subunit may have a very specific role in the development and turnover of olfactory and vomeronasal neurons.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8, Gamma-9.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.