PharMolix/UniProtQA huggingface dataset:
Protein: NTPPA_CHLCV
Sequence: MEPQLILGSSSPRRKSILQYFRIPFTCISPSFEERSVPYQGDPAAYSQELAVGKAESIVQDHNPEGVILTADTVVIYKGKVFNKPSSRDEAIEMLKTLSGQTHSIITSVALLQQKKLMVGQETTQVTFNQLPEKYLGRYVEAFSTLDKCGGYSTQEGGGLIIHNIQGCAYNVQGLPIRTLYHLLLEFDINLWDYLV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEQA_SHEDO
Sequence: MKYIEVDEELYRFIASKTERIGESASDILRRLLTLPVDTVTPFEPNAIDEPSLDVAHHQASNFAASNQEQQTGHGHAGEPSAVQTPESNDYAKAQPHSSGYQPGQLEGHKSEPQTLAQLNSQPLAVGQSSQSATSQVDFNALVNEHLLSQQKGAVGRFMWLLEGLAALAPSQFNKVLLVQGKGRLYFARSKDELLASSASANPKEIGTTGYWVTTNNNTAKKQAILVEVLTKLHCDETLASAIADRICDKVAG
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_MARPO
Sequence: MEHRIYNSNYFLDITIPYFFHPEILIRIFRRHIQDIPFLHFLRTLLYKNKCLNILNIENFFYLKKNQFFCFLWNFYIYEFEYLLNDIWEKFYKFESVFFWNFIDKTNSIKKIKHILKKSKKPIEKKIVKKISSIHYIRYKNNLIITLNDRNILILENWKDFFLIFWQKYFNVWFKSSRILIQNFYKNSFSFLGYMFRIESQIILIQIQIINLLRNVNLIKKEFCSIIPVIPLIRLLAKEKFCDVLGRPLCKLSWTTLSDNEIFERFDQIIKHIFSYYSGCINKKGLYQLQYIFRFSCAKTLACKHKSTIRTVWKKYGSNLLTSSIFFNKTKLISLNFSNKNPYKKNFWYLNIIQVNYLAHSLQKSKLLKE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CINA_LISIN
Sequence: MASAEIIAVGTELLLGQIVNSNAAFISEELAANGIYVYHHTVVGDNPKRLKDVIDIAEKRSDILIFTGGLGPTEDDITKQILAEHLQKNLVEDAFHMNEITEYFASRNRTMTENNKLQAVIIEGSTVLNNDYGFAAGMFLKENNHTYILLPGPPSEMKPMFSSYAEPLLVSENTEKNVLESKIMRFFGIGESQLAADLNDMILAQVNPTIATYAGDNEVVVRITATAKTKEEASALVNETEQEILRRDGTFLYGYGEVSLPELVTAMLLEKNITISAAESFTAGLFQAEIARFPGISKIFKGGMVTYSEETKQSILEVSPQTIKENGVVSSECAKEMAKNVSRLCNTDIGISFTGVAGPDSLEGHPAGTIWIGLHVAGFETEAYQFVYGRDRNHNRRRAVKQGFQLIKQFLDTNK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: SYL_BURM9
Sequence: MHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYENIAYMKKQMQAMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGAFVEKREIPMYYMRITQYADELLNDLDGLGWPERVKVMQHNWIGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLARDKPALQAFIDECKRGGVAEADIATMEKKGVATGFSVSHPLTGEPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAYDAAVDAIAAELKAGGLGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGTGNPLAKSDAFLNCTCPKCGAVAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKSDGQPVELGGIEKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDAAQLAEAGKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTFELWKVLGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAAVADGMFAKFAEGRPAKKIIVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ACIBY
Sequence: MKQPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLEVPVEKAQQALKGVMMELDDCAFPLLAGMIGTDDPKVAFKDADYALLVGSRPRGPGMERADLLKVNGEIFIGQGQALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALTQVAQKAGVAVADIEKLTVWGNHSPTMYADYRFATANGESLKDKINDPAWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGEYKIVQGLEIDEFSRERINFTLNELEEERAAIADMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RRG7_KLULA
Sequence: MSWKGVFASSFPKDTLQKYIAANESIANSTVFQGTLYELTVVRELMNKLRLEDMQVVGGSYDGGIDIRGKWNVLPLTKAIEMQIQFDELPKRLKLPTTSIKPWKHRVKPDKYLDCYIQCKAFNSDKVTGRQVRELIGSFSMQVPARKRNSSIMIMSSPTLFTKDGIRLFNEAAIPMVFTKVDMIQRLADGSFDVKNSGKLQHYYENDYASKLLANCGIKEWLKLKGYESLAQK
What are the official names of this protein?
Required for respiratory growth protein 7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COAX_PORGI
Sequence: MSFNLIVDQGNSACKVAFVRNNSIESISFLPGKAGQALSHLVAPHRFDKAIYSSVGLPDEEAEAIVRSCAAASLMMGTETPVPLRLQYDRRTLGADRLAAVVGAHSLYPNTELLVIDAGTAITYERVSAEGIYLGGNISPGLHLRFKALHLFTGRLPLIDPSGISPKIAEYGSSTEEAITAGVIHGLAGEIDRYIDDLHAKEGRSAVILTGGDANYLARIIRSGILIHPDLVLLGLNRILEYNV
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPD_PECCP
Sequence: MSDASSTILFEYPLNEKTRTWLRIESLLQQLHQNHSLTDMGSALTFFRAIAELLDVLERGDVRTELLKELERQQQKLLQWSDVPGVDMERIHTLRRQLKDLASTLMAAPRMGQFLREDRLIGMVRQRLGIPGGCCSFDLPTLHSWLHQPQELREKLVSGWLSSLSPLKQALDMILELIRHSGIFRPQISLNGFFQDNASDADLLRLRLEQAHQLYPQISGHKTRYAIRFLPLDSENGHIPPRLTFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: PYRC_SALPA
Sequence: MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGSDNLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RLMD_PSEU2
Sequence: MAKHERGLRFQPAGGVKTVQIPAGKKQRLTIERLSDDGRGIAFLEGKTWFVAGSLAGEEVEARVLNARGKVVEARTERVFTASAMRRAPACEYFGRCGGCSVQHVPHEEQLALKQRMLAEQLLRVANVVPDEWAAPLSGAELAYRRRARVAVRWDAKAKRLDVGFRAAASQDIVSIEHCPVLVQALQPIMNELPGMLKSFSKPQVLGHVELFSGVATAVLLRHTASLVEADLALLQAFCSRHGAQLWLHGEGEPQPASPGDTLGYRLEPWNLQLAWRPGDFIQVNASVNTAMIEQALQWLAPAKDERVMDLFCGLGNFALPLAGLARDVVAVEGVATMVERAAVNAMSNDLHNVRFFQADLSQPLTQADWAAEGFSAVLLDPPRDGAFEVVRQIRKTGARRLLYVSCNPATLARDAVELIRQGYRLKRAGILDMFPQTAHVEAMALFEMSK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: LAMP2_MOUSE
Sequence: MCLSPVKGAKLILIFLFLGAVQSNALIVNLTDSKGTCLYAEWEMNFTITYETTNQTNKTITIAVPDKATHDGSSCGDDRNSAKIMIQFGFAVSWAVNFTKEASHYSIHDIVLSYNTSDSTVFPGAVAKGVHTVKNPENFKVPLDVIFKCNSVLTYNLTPVVQKYWGIHLQAFVQNGTVSKNEQVCEEDQTPTTVAPIIHTTAPSTTTTLTPTSTPTPTPTPTPTVGNYSIRNGNTTCLLATMGLQLNITEEKVPFIFNINPATTNFTGSCQPQSAQLRLNNSQIKYLDFIFAVKNEKRFYLKEVNVYMYLANGSAFNISNKNLSFWDAPLGSSYMCNKEQVLSVSRAFQINTFNLKVQPFNVTKGQYSTAQDCSADEDNFLVPIAVGAALGGVLILVLLAYFIGLKRHHTGYEQF
What is the function of this protein?
Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live (PubMed:10972293).  Functions by binding target proteins, such as GAPDH, NLRP3 and MLLT11, and targeting them for lysosomal degradation (By similarity).  In the chaperone-mediated autophagy, acts downstream of chaperones, such as HSPA8/HSC70, which recognize and bind substrate proteins and mediate their recruitment to lysosomes, where target proteins bind LAMP2 (By similarity).  Required for the fusion of autophagosomes with lysosomes during autophagy (PubMed:27628032).  Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes (PubMed:27628032).  Required for normal degradation of the contents of autophagosomes (PubMed:10972293, PubMed:12221139).  Plays a role in lysosomal protein degradation in response to starvation (PubMed:27628032).  Required for efficient MHCII-mediated presentation of exogenous antigens via its function in lysosomal protein degradation; antigenic peptides generated by proteases in the endosomal/lysosomal compartment are captured by nascent MHCII subunits.  Is not required for efficient MHCII-mediated presentation of endogenous antigens (By similarity).
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 2, LAMP-2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, Lysosomal membrane glycoprotein type B, LGP-B.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Protein: NFUA_ECOBW
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: AROC_ROSCS
Sequence: MPGNTFGQVFRLTTWGESHGPAVGCVVDGCPAGLDISEDYIQHELNRRRVGQSRVTSARQESDQVQILSGVFEGRATGAPISMLVFNTDAKPGHYENIKDLYRPGHADYTWDVKYGFRDWRGGGRSSARETIGRVAGGAVAKRLLAQHGVSIIAWTAQLGDLKAEVIDESEIERNIMRCPDARVAALMVERVEQARRSLDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIKGVEFGEGFGVAHMTGSVHNDPFERRADGTIGTSSNHHGGILGGISTGEEIVLRIAAKPPASIARLQRTVDREGNPTEIEIHGRHDPTVLPRLVPIAEAMLALVLADHLLRQRLARMER
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DAPE_XYLFT
Sequence: MSDVLDLACDLISRPSMTPDDAGCQEMIAKRLERAGFICEHLRYAAVSNLWATHGRGAPVLVLLGHTDVVPPGPVEAWTSDPFMPDMRNGILYGRGAADMKGSVAAFVIAAERFLAAYPQHPGTLAILLTSDEEGQAIDGVRKVAETLRQRGQGIDWCLTGEPSSSKRLGDLLRVGRRGSLSATLHVKGVQGHVAYPHQARNPIHLALPAFAALTARHWDDGYESFPSTSLQISNIHAGTGANNVIPGALEVAFNLRYNPHWIAPRLESEIVALLDQHGLDYTLHWHRSGEPFYTPEGKLRRIAREVLERFSGAPPEESTGGGTSDARFIAPLGAQCIEVGPVNASIHQVDEHVCLSDLEALPDLYQLLIERLLAEH
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LIPB_PROM1
Sequence: MDKKLHSVSPESGPNSNLDLTPQLAQSSSAFLFEPKNIVPFETALGWQKNFLKNLIEEPFSPQAVWLLEHFSCFTMGRGSDKKNLLFEENNSPLPVFSIERGGEVTHHMPGQIVGYLVLNLSLHKKDLAWYLRELEQVLIDVLDLLGIEGKRVDGLTGVWCEDKKVGSIGIGCKRWVTQHGFSLNVDCDLIGFEKIIPCGLDKVKVGKLSDWIPGIKVCDVTPLLRESVKRRFKLNWEKINQSL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SO1A6_RAT
Sequence: MGEPEKRAGTHGIRCFAKIKVFLLALTWAYASKALSATYMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKRHRPIMIGIGCAVMGLGCFIISLPHFLMGRYEYETTISPTSNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATIYVDMGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPEDMANETKNDEGDKHREKAKEEKRGITKDFFLFMKSLSCNPIYMLCVLTSVLQVNGFVSIFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKITLKKAAFISYCLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNTRCSCLTKTWDPVCGDNGLAYITPCLAGCEKSVGSGINMVLQDCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIITVFCSFFYSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRILGGILAPIYFGVLIDRTCLHWGTQKCGEPGACRTYEINSFRSIYLGLPAALRGSSYLPAFFILRLMRKFQFPGDINSPVTDHVEMMLTEKESEHTDVHRSPQVENDGELKTKL
What is the function of this protein?
May mediate the Na(+)-independent transport of organic anions.
What are the official names of this protein?
Solute carrier organic anion transporter family member 1A6, Kidney-specific organic anion-transporting polypeptide 5, OATP-5, Solute carrier family 21 member 13.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXB_HAHCH
Sequence: MTPISERPIRIGIVAGEASGDLLGAGLMQEIKALYPQATFEGIGGERMLKEGFNTFFQMERLSIMGLVEVLGRLPELLAMRRRIVDHFTATPPDLFLGIDSPDFTIGIELKLRQAGIKTAHYVSPSVWAWRQNRVFKIAKAVDLMLTLLPFEARFYREHNVPVKFVGHPLAEIIPLHPDKVAMRHELGIDASGEVIAVLPGSRGGEVSRLGPTFIETIAWLHQRRPDVRFVIPAANQARKTQIEQQLQSHGGRLPVTLIDQHSRECMMAADAILLASGTATLEAMLVKRPMVVAYKLATLSYWIMRRLLKAKYISLPNLLADKALVPELIQNDATPAKLGEALLKELNVERRRSLEDEFEGLHKLIRQNASVAAAQAVAELIEKGRVATHDAREGH
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: COBQ_CUTAK
Sequence: MTGILVAGTSSDAGKSLVVTALCRVARRRGVDVVPFKAQNMSNNSMVCADGSEIGRAQYLQATAAGVTPTSAMNPVLLKPGTDRRSFVVLRGKPGGVLEAGEYTTGRRYLAEAAWAAYDELAASHDMVICEGAGSPAEINLRRGDYTNMGLARAKNLPVVLVGDIDRGGVLASLFGTWALLDDDDRALLAGYIVNKFRGDDAILAPGLEEITDRTGMPSFGVLPWVPGVWLDGEDALEVGRWRHEGDAVDPSSLRVAVVRFPRISNATDVDAMAGETGVDVQVTTNPDTCQAADVLVLPGSRSTVSDLEWLRRSGIADVVARRAEQGRTVVGICGGYQMLCRTILDPDGQETTPGSVVEGLGLLPVEVDFAATKTLALSHGTWRGIEVGGYEIHHGVCRSLEDAEAFLDGVHVGPVWGTMWHGAFEHDEFRRTWLADAARHAGSSWRPHSDELGYQARREAMIETLADALEAHVDVDRILHLVR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RSSA_ORNPR
Sequence: MSGGLSVLGLKDDDVRRFLTAKTHIGTAQLDFQMQQYCFKRRSDGVYLIDLKKTWEKLLLAARAIVAIENPAEVCAISSRPYGQRAVLKFASFTGATPIAGRFTPGTFTNQIQAAFREPRLLVVCDPREDHQPVTEASYVNIPVIAFCNTDACLRYVDVAIPCNNKAQHSIGLMWWMLTREVLRMRGSIIREIPWDTMVDLFFYRDPEEAEKEEQTQVVPERSIKEAPEFPPDQWGVGDTAAVQPEVADWSTAAEIPFQSAPAPAPAPAPATDDWASTGTATVGPTTEWGAATDNSWAS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYRA_STAAC
Sequence: MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFEVTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFNTFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVGLMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLIFLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHVNDDEETNHTEAEKSSSNIKDAEKTGVATASTVGVAKNDTENTVADEPSIHEGTEKTEPQHHIGNQTESNHDEDHDITSESVESAESVKQAPQSDDLTNDSNEDEIEQSLKEPVTYKEDRRSSVVIDAEKHIEKTEEQSSDKNK
What are the official names of this protein?
Lysostaphin resistance protein A.
What is the protein family that this protein belongs to?
Belongs to the LyrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL23_CHLTA
Sequence: MKDPYDVVKRHYVTEKAKMLEGLSLGDGEGKKKGSFCKDPKYIFIVAGDATKPMIAEAIEAIYSAKGVKVKKVNTMCVKPQPTRIFRGRRKGRTAGFKKAIVTFVDGHSIG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL11_STAAR
Sequence: MAKKVDKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTQDQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGIEKGSGEPNKTKVATVTKDQVREIANSKMQDLNAADEEAAMRIIEGTARSMGIVVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ATG18_DICDI
Sequence: MNVGGKFNEGILFLNFNQDFSCIAVGTPEGYKIFNSDPYTLYYSQSNGGAGLVEMLFSTSLVSIVGSGDGNTSQRRLLINNIKNNIPICDLNFVTAILSVKMNRKRIVVIMETKIHIYDINNMKLLETREIASNPKGLCALSPSNTNYIVYPASQNNGNILVMDVLTLETVNLIQAHKSQISALALSQDGTLLATASDKGTVIRVFALPYANKSLSFRRGSIPAIIHSMTFSLDGRYLCVSSDTGTIHIFKIDFSSSNSSSFHQAQPSSSPSGGMMGLNFGGLTSKMSSYLPEVISQVWEPSRDFAHIKIPPGIPSICALMQNNKTAMVLTADSLYMQYNFDESVGGELKLAKEFSLLMEPDLDNDVTAKIL
What is the function of this protein?
May be involved in cytoplasm to vacuole transport and autophagy.
What are the official names of this protein?
Autophagy-related protein 18, WD repeat domain phosphoinositide-interacting protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: RUVB_SACD2
Sequence: MIEQDRIIDANAKSREEQIDRAVRPKSLKEYIGQPVVREQMEIFIGAAQARGDSLDHTLVFGPPGLGKTTLANIIAAEMGADLKSTSGPVLEKAGDLAALMTNLEPGDVLFIDEIHRLSPVVEEILYPAMEDFQLDIMIGEGPAARSIKLELPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYNIEDLTHIVERSASLMGVAMDTPGAREVAKRSRGTPRIANRLLRRVRDYAEVKSDGTVTAQIADLALNMLNVDEHGFDHMDRRLLLTLIEKFGGGPVGVDSLAAAISEERDTIEDVLEPYLIQQGFIMRTPRGRMATQLAYQHFGLNVPAALKQDSLPGI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YQGF_BACC0
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYX_XANOR
Sequence: MHEQLSPRDQALEARLVELETRLSFQEQALNELSEALADARLTGARNAELIRHLLDDLGKVRSTLFADAADEPPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.