PharMolix/UniProtQA huggingface dataset:
Protein: MOBA_RHOCA
Sequence: MRIAGIILAGGQGRRMGREKALVPLSGVPLIARVLALAPQVEAVAISANGDPGRFGLGLPVLPDRPGESGLGPMAGIRAGLDWAAGIGAEALVSTATDTPFLPEDLVERLAAAAPAHAQSFGRDHYTAALWRVATVPRIDALFAADERRIARLSGGAVAVPFDTTPDPFANLNTPEDLARAEDRLRQNAP
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPA2L_HUMAN
Sequence: MGSSSLSEDYRQCLERELRRGRAGVCGDPSLRAVLWQILVEDFDLHGALQDDALALLTDGLWGRADLAPALRGLARAFELLELAAVHLYLLPWRKEFTTIKTFSGGYVHVLKGVLSDDLLLKSFQKMGYVRRDSHRLMVTALPPACQLVQVALGCFALRLECEILGEVLAQLGTSVLPAEELLQARRASGDVASCVAWLQQRLAQDEEPPPLPPRGSPAAYRAPLDLYRDLQEDEGSEDASLYGEPSPGPDSPPAELAYRPPLWEQSAKLWGTGGRAWEPPAEELPQASSPPYGALEEGLEPEPSAFSFLSLRRELSRPGDLATPESSAAASPRRIRAEGVPASAYRSVSEPPGYQAHSCLSPGALPTLCCDTCRQLHAAHCAALPACRPGHSLRVLLGDAQRRLWLQRAQMDTLLYNSPGARP
What are the official names of this protein?
Spermatogenesis-associated protein 2-like protein, SPATA2-like protein.
What is the protein family that this protein belongs to?
Belongs to the SPATA2 family.
Protein: RPIA_CHLMU
Sequence: MSKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLAITAVASSRISHLLAQALGIPFLDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKILLQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKVLNQQGYIGDWRKTSHGERFITDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MPRIP_RAT
Sequence: MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSSGSSSSSSSSSIPSAEKVPTTKSTLWQEEMRAKDQPDGTSLSPVQSPSQSQPPAACTPRETGLDSKEDENILSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPLLSPPSPSTPHSRRSQVIEKFEALDIEKAEHMETNMLILTTPSSDTRQGRSERRAIPRKRDFASETPTAPLSDACPLSPHRRAKSLDRRSTESSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPTSAPDVTSSLPEGKNKSTSFDTCLRPSEKQEAEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERASTVGSSDSGDPGCLEAEPGELERERARRREERRKRFGMLDTNDGPGMEDTALRMDIDRSPGLLGTPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTREGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSVIEQVSWDN
What is the function of this protein?
Targets myosin phosphatase to the actin cytoskeleton.  Required for the regulation of the actin cytoskeleton by RhoA and ROCK1.  Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin.  Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells (By similarity).
What are the official names of this protein?
Myosin phosphatase Rho-interacting protein, Rho-interacting protein 3, RIP3, p116Rip.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin.
Protein: RL32_SHEDO
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGELHLRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TYW3_XENLA
Sequence: MEKQEAFSHWKQQSARKTDVSKKGSVDEDIEETVRLINQQERYFTTSSCSGRVIIINETLDNSTIQKQNCSWLFVTHKLCKPDDVFAALQNATGDVVLKFEPFVLHVQCRALEDAQLLHSVAINAGFRNSGITVGKKGKIIMAVRSTHGLEVPLTQNGKCLVSHEYIEFLVHTANKKMEENKRRITRFHSCLHKALQKEDCVHDKTSKEQASSCVYVRRRKRKDRSRKSNCSSSEEEHTDSEPELTLFNDP
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3, tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: SSH4_ASPCL
Sequence: MRGSEASGPGALLGAASTLTTSVIRNPTSIPTSSAPIPSTDAGLVAKNVEHVLMSLTAQNDGGLVSVSGNSSGSTGKGILIGVLSAFGSAVVAVIVLAIFFFFKYTRRGRIMLDRIGRPGEFDDEQAFAREEAEALEVMDDLSRSEYMRAKAFVEAYPPESMQTDISLSQFLAIQEKGVSAWEFQPELEIANCFVEGRTEIEFYDSECSVQTNLPVPKQNDVYYWEAKIYDKPENTLVSVGMTTKPYPLFRLPGFHKYSVAYSSTGHRRHNQPFASTPYGPPLSQGDVIGVGYRPRSGTIFFTRNGKKLEDVVHAAKTQNFFPTVGANGPCTVHVNFGQMGFVFIEANVKKWGLAPMTGSLAPPPPYGSEQGSILLESGRESAAQISQRVYQEAGYARTNSTVRIPPSRSPGPVRSPTDISLAQLAHIPSHEDVGEGSSQANTIDGEQTPLLNTNDLDDQVPPPEYSSPDGSRRGSDIAGDLPRQGSPPIPSYDAAVGNHSGDTARSDSEP
What is the function of this protein?
Components of the endosome-vacuole trafficking pathway that regulates nutrient transport.  May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).
What are the official names of this protein?
Protein ssh4.
What is the protein family that this protein belongs to?
Belongs to the SSH4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: HIS6_RHILO
Sequence: MLKARVIPCLDVKDGRVVKGVNFVDLIDAGDPVEAAKAYDAAGADELCFLDITASSDNRETIFDVIARTAEQCFMPLTVGGGVRQVADIRKLLLAGADKVSINTAAVKNPDFVAEAADKFGNQCIVVAIDAKKVSGAGEADRWEIFTHGGREKTGIDAVEFARKMVDRGAGEILLTSMDRDGTKAGYDIALTRAIADAVRAPIIASGGVGTLDHLVEGIRDGHAGAVLAASIFHFGTYTIAQAKAHMAAAGLPMRLDSSGDRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CLOAB
Sequence: MASGYRKLGRPTDQRRAMLRNLVTSFLKHGKIETTVTRAKETRSLAEKMITLAKRGDLHARRQVLSFVTEETVVKKLFDEVAPKYSERNGGYTRIYKMGPRRGDGAEIVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL18_DESVM
Sequence: MTMTKNDARKRRKVRIRKKIAGSTERPRLVVYRSNLHVYAQIVDDATGATLVATSTLAIGKAQAGAHCNKAGAELVGKEIARLAGEKSIKRVVFDRNGYLYHGRIKAVADGAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y2131_STAA8
Sequence: MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASVSFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSAEYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFIIAYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK
What are the official names of this protein?
UPF0316 protein SAOUHSC_02131.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GUAA_STAA2
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RIMO_LEGPH
Sequence: MNHKVGFVSLGCPKALVDSERIITQLKAQGYELVPTYQDAGVVVINTCGFIDSAVQESLDTIKEAMAENGRVIVTGCLGAKADVIKNACPDVLHISGAHAYEEVVNAVHQYLPPPADPFTQLIPPQGIKLTPRHYAYLKISEGCNQKCTFCIIPTMRGKLQSYPMAQILTEAKKLKQAGVKELLVISQDTSAYGVDTRYQQVEWQGKTVNTRFYDLCEQLGELGIWVRLHYVYPYPHVDDIVPLMRDGLILPYLDIPLQHANSRILKAMKRPASSENTLLRIASWREICPDITLRSTFIVGFPGETEEEFSELLAFLKEAQLDRVGCFKYSPVEGAKANDLDNPVSEDIKEERYHRFMQVQAEISRNKLKNKIGSTQTVLIDEINDDQIIARSKSDAPEIDGLVYLPKTSGITVGSFAEVVITDSDDYDLYASLV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y474_PSEAE
Sequence: MMNVPEGFQPLFRSSPLLDLLGPFFCRQDAQRQLVVALRIDEKHCNHGGTAHGGLLSTLADVGLGYAMAFSREPPQPMVTVGLRLDFCGVARVGDWLEVHTRVDKLGQRMAFASARLHSGERLVASASGVFHLP
What are the official names of this protein?
Putative esterase PA0474.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: SVMI2_ATHNI
Sequence: EDDHDHHHHHHHHHHHHGVGGGGGGGGGGA
What is the function of this protein?
May serve as a metalloproteinase inhibitor during glandular storage.  Their inhibition may be instantly disengaged, by dilution or physiochemical change, when venom is injected into tissue of the victim.
What are the official names of this protein?
Poly-His-poly-Gly peptide 2, pHpG 2.
What is the protein family that this protein belongs to?
Belongs to the pHpG family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_COXBN
Sequence: MEFRVIIPARFDSTRLPGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGTERIAEAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLAEDLDEHDNVKVASLCTPITEVDELFNPHSTKVVLNRRNYALYFSHAPIPWGRDTFSDKENLQLNGSHYRHVGIYAYRVGFLEEYLSWDACPAEKMEALEQLRILWHGGRIHMVVAKSKCPPGVDTEEDLERVRAYF
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_HELAH
Sequence: MADVVVGIQWGDEGKGKIVDRIAKDYDFVVRYQGGHNAGHTIVHKGVKHSLHLMPSGVLYSQCKNIISSAVVVSVKDLCEEISMFENLENRLFVSDRAHVILPYHVQKDAFKEKSQNIGTTKKGIGPCYEDKMARSGIRMGDLLDDRILEEKLKVHFKAIEPFKEAYDLNETYEKDLREYFEQYAPKIRPFIKDTTSMLIEANQKGEKILLEGAQGTLLDIDLGTYPFVTSSNTTSASACVSTGLNPKAINEIIGITKAYSTRVGNGPFPSEDTTPMGDHLRIGGAEFGTTTKRPRRCGWLDLVALKYACALNGCTQLALMKLDVLDGINEIKVCVAYERRGEKLETFPSDLKDCVPIYQTFKGWEKSVGVRKLDDLEQNTREYIRFIEEEVGVKIRLISTSPEREDTIFL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPOT_SYNY3
Sequence: MNAVAALPTPTIHTTCAQDIHDIELPQWLEDCLQQWQREIEQGQDETTAPHCLICRAFCFAYDLHAQQRRKSGEPYIAHPVAVAGLLRDLGGDEAMIAAGFLHDVVEDTDISIEQIEALFGEETASLVEGVTKLSKFNFSSTTEHQAENFRRMFLAMAKDIRVIVVKLADRLHNMRTLDALSPEKQRRIARETKDIFAPLANRLGIWRFKWELEDLSFKYLEPDSYRKIQSLVVEKRGDRESRLETVKDMLRFRLRDEGIEHFELQGRPKHLYGIYYKMTSQDKAFEEIYDIAALRIIVESKGECYRALSVVHDVFKPIPGRFKDYIGLPKPNRYQSLHTTVLGLTSRPLEIQIRTEEMHHVAEYGIAAHWKYKESGGSENATLTSTDEKFTWLRQLLDWQSDLKDAQEYVENLKQNLFDDDVYVFTPKGEVISLARGATPVDFAYRIHTEVGHHMKGARVNGQWLGVDTRLKNGDIVEIVTQKNSHPSLDWLNFVVTPSARHRIRQWFKRSRRDENILRGRELLEKELGKTGLEALLKSEPMQKTAERCNYQNVEDLLAGLGYGEITSNSVVNRLRENNVNNVKNSQSSQEVTLASSPQVHPPTPPATGKDNSPIAGIEGLLYHIAGCCHPLPGEPIMGVVTRGARGISIHRQGCHNLEQMDGDRLIPVRWNPNTNNHQTYPVDIVIEAIDRVGVLKDILSRLSDNHINVRNADVKTHLGRPAIISLKIDIHDYQQLLGIMAKIKNMSDVMDLRRVISG
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the degradation of ppGpp into GDP.  It may also be capable of catalyzing the synthesis of ppGpp (By similarity).
What are the official names of this protein?
Probable guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: CP124_MYCBO
Sequence: MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATLRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKTLPVTWS
What is the function of this protein?
Primarily hydroxylates the omega-carbon of a number of methyl-branched lipids, including (2E,6E)-farnesol, phytanate, geranylgeraniol, 15-methylpalmitate and (2E,6E)-farnesyl diphosphate.  Also catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25R)-26-hydroxycholest-4-en-3-one (alcohol), (25R)-26-oxocholest-4-en-3-one (aldehyde), to finally yield the carboxylic acid (25R)-3-oxocholest-4-en-26-oate.  Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one.
What are the official names of this protein?
Methyl-branched lipid omega-hydroxylase, Cholest-4-en-3-one C26-monooxygenase, Cholest-4-en-3-one C26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming], Cholesterol C26-monooxygenase, Cholesterol C26-monooxygenase [(25R)-3beta-hydroxycholest-5-en-26-oate forming], Cytochrome P450 124, Steroid C26-monooxygenase, Steroid C27-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SYL_THEP1
Sequence: MKEYRPQEIEKKWQEVWEEKKVFYTPQRSEKPKYYALVMFPYPSGTLHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAFGLPAENAAIEKGIHPEEWTRKNINTIRGQVKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPKCKTVLANEQVKDGKCERCGTSVTIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMALAPESPLVEELVLEEKKEDLQEFLERVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIPIYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADRDLDPEKMEEAYEGEGIMVNSGPFDGTPSSEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCEKCGVVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKRTKCPICGGEAQRETDTMDTFVDSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYLNFDEPFTNLFTQGMIYKDGAKMSKSKGNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFIKRLWNTFYTVLPFVKEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSVPQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNDSLVVQQAWPSYDPKALEVEEVEIAIQINGKVRDKVVVPVDISEEALKRIVLERERVKEYVDGKPIRKFIYVKGRIVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIC_ECOLI
Sequence: MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN
What is the function of this protein?
PPIases accelerate the folding of proteins (Probable).  It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase C, PPIase C, Par10, Parvulin, Rotamase C.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y962_YERPP
Sequence: MSELCPCGSILNYHECCGPYILGTQVAAKPAILMRSRYCAYVEKNVDYLIATWHPDCHAQEWRESIIQGFTKTVWHGLTVIAETPGRHPDEAFVEFIARFTDADNAQITAMHERSRFLRIKEHWYYIDGIRPSLGRNDTCLCGSGKKHKKCCGR
What are the official names of this protein?
UPF0225 protein YPDSF_0962.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: ACPS_RHIE6
Sequence: MIIGIGSDLIDIRRVEKSIERFGERFTHRCFTEIERARSDRRANRAESYAKRFAAKEACSKALGTGLAQGVFWKDMGVVNLPSGKPTMVLSGGAAVILESMLPAGHRAAIHLTITDDYPLAQAFVIIEALPESL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN410_MOUSE
Sequence: MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDETPNHANSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQKSPEFLTTPESPSLLQDLQPSDSTSFILLNLTRAGLGSSAEHFVFVQDETEDSGADFLSAESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTGSNGENVHLGSGDGQPKDSGPLPQAEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNERSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGTTGSQEQDQTAEPLMGSSLLEDASVPNKNLVSMNSQSSLGGESLNLSNTNSILGVDDEVLTERASRPLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERQT
What is the function of this protein?
Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells (PubMed:33859416).  Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells (PubMed:33859416).  May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence (By similarity).  May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose (By similarity).  However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4 (By similarity).
What are the official names of this protein?
Zinc finger protein 410, Another partner for ARF 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Directly binds to the sequence motif 5'-CATCCCATAATA-3'.
Protein: YFDC_ECOLI
Sequence: MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHIRQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFQVELEGVPGSFLLENLGYTFGFIIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLIRLWGVVLLGNILGTGIAAWAFEYMPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIILMTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMSHAQIRNDMSNKRKAEARQKAERAENIKKNYKNPA
What are the official names of this protein?
Inner membrane protein YfdC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU5M_MACFA
Sequence: MIMHTPIMMTTLISLTLPIFATLTNPYKKRSYPDYVKTTVMYAFITSLPSTTLFILSNQETTIWSWHWMTTQTLDLTLS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AQP2_ELEMA
Sequence: SIAFSRAVFSEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQTLGHISGAHINPAVTVACLVGCHVSFLRATFYLAAQLLGAVAGAALLHELTPPDIRG
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: SYE_STRSV
Sequence: MTKAIRVRYAPSPTGLLHIGNARTALFNYLYARHYGGTFIIRIEDTDRKRHVEDGERSQLENLRWLGIDWDESPETHENYRQSERLDMYQKYVNELLDKGLAYKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAVNETGVYKWTDIVKGEIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHLMEISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYLPEAVFNFIALLGWNPGGEHEIFSRQELIELFDEKRLSKSPAAFDQKKLDWMNNEYIKNADFDTIFALAKPYLEEAGRLTDKAEKLVELYKPQMKSVDEIVPLTDLFFADFPELTDAEREVMAGETVPTVLTAFKEKLEAMSDADFVTENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPDTIYLLGREKSIQHIENMLNQIQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.