PharMolix/UniProtQA huggingface dataset:
Protein: LCE5A_HUMAN
Sequence: MSCQQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPKCPPQCSAPCPPPVSSCCGSSSGGCCSSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCHSSGGSGCCHSSGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 5A, Late envelope protein 18, Small proline-rich-like epidermal differentiation complex protein 5A.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: CS120_WHEAT
Sequence: MENQAHIAGEKKGIMEKIKEKLPGGHGDHKETAGTHGHPGTATHGAPATGGAYGQQGHAGTTGTGLHGAHAGEKKGVMENIKDKLPGGHQDHQQTGGTYGQQGHTGTATHGTPATGGTYGQQGHTGTATHGTPATGGTYGEQGHTGVTGTGTHGTGEKKGVMENIKEKLPGGHGDHQQTGGTYGQQGHTGTATHGTPAGGGTYEQHGHTGMTGTGTHGTGEKKGVMENIKDKLPGGHGDHQQTGGTYGQQGHTGTATQGTPAGGGTYEQHGHTGMTGAGTHSTGEKKGVMENIKEKLPGGHSDHQQTGGAYGQQGHTGTATHGTPAGGGTYGQHGHAGVIGTETHGTTATGGTHGQHGHTGTTGTGTHGSDGIGEKKSLMDKIKDKLPGQH
What is the function of this protein?
May reduce intracellular freezing damage during winter by hydrogen-bonding to the lattice of the nascent ice crystals, thus modifying the structure and/or propagation of ice crystals.
What are the official names of this protein?
Cold-shock protein CS120.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: ATP9_SOLLC
Sequence: MLEGAKLMGAGAATIALAGAAIGIGNVFSSLIHSVARNPSLAKQLFGYAILGFALTEAIALFALMMAFLISFVF
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NOP10_CAEEL
Sequence: MFLRYFLDENQQRVYTLKRTAPSGEQTLTAHPARFSPEDKNSKYRIIIKKRFGLLPTQKAKTVC
What is the function of this protein?
Required for ribosome biogenesis.  Part of a complex which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Putative H/ACA ribonucleoprotein complex subunit 3, Nucleolar protein 10, Nucleolus associated protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RLMN_YERP3
Sequence: MSEQLLTASTSIDAAPLSDNTVQTTAPATSKINLLDLNRQQMREFFAEMGEKPFRADQVMKWMYHYCYDDFEQMTDINKGLRAKLQRVAEIRAPEVAEEQRSVDGTIKWAIKVGDQQVETVYIPEADRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGSLKSTGTRPITNVVMMGMGEPLLNLNNVVPAMDIMMDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRDEIVPINRKYNIETFLAAVRRYLDKSKANGGRVTVEYVMLDHINDSTEQAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVIDRTKRTLKKKMAGEPIAIKTV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_ECOBW
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: HPR3_ARATH
Sequence: MAESSEPPVVLLHRPPSLTFMDEILTREFRTLITDTSSSESLPSFFPRHASSARAFVISGRLPVTDELLSHLPSLQILVCTSVGIDHIDLAACKRRGIVITNAGNAFSDDVADCAVGLLISVLRRIPAADRYVRSGNWAKFGDFQLGSKVSGKRVGIVGLGSIGSFVAKRLESFGCVISYNSRSQKQSSPYRYYSDILSLAENNDVLVLCCSLTDETHHIVNREVMELLGKDGVVINVGRGKLIDEKEMVKCLVDGVIGGAGLDVFENEPAVPQELFGLDNVVLSPHFAVATPGSLDNVAQIALANLKAFFSNRPLLSPVQLD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate (HP) into glycolate and glycerate.  Mostly active in the presence of NADPH and glyoxylate.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase HPR3, NAD(P)H-dependent hydroxypyruvate reductase 3, AtHPR3, HPR 3.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
Protein: ZAPC_PSET1
Sequence: MLQASKQWQWISCAKKNRLLLDLNEDMQLCTPYKLRQLTDSTFKNPYFSLEDAAFYEQVYQYLVQFKLWNPAQLCQISLNATAVKFQLKPVLAKSWFFEQYTGSTPSTEAVINLTSKAQSGEFLIVEHSSDASVCINLSENFQLDDNLSLVQFEAIRVLNNRVHPLLNQHIHSKIA
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_XANAC
Sequence: MTYRDAGVDIDAGNALVERIKPLVKRSFRPEVMGGLGGFGALFDLSGKYKEPVLVSGTDGVGTKLKLAQQLGRHDTIGIDLVGMCVNDVLVQGAEPLFFLDYFATGKLDVDTAAAVVGGIARGCELSGCALIGGETAEMPDMYPPGEYDLAGFTVGAVEKSQLLDGAQVREGDVLIGIASSGPHSNGYSLIRKIYERAGAPAEHVLDDGTKLIDALMAPTALYVKPVLALLKSHGEAIHAMAHITGGGLTENIIRVIPEGLGLEIDATAWTLPPVFAWLQREGAVADAEMWRTFNCGIGFVLVAAPAQAAALEQALDAQSLAHWRIGQVVTAHGDERVRIG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND1_CAEEL
Sequence: MQIWHMEPFPCGDRRLPHHVFPPKKITTTQLGQLAGVQYYKVDLDDTASMKKRLSAVKTEKNVTFTDMFTVSETMLEFDDKMEQFYEPQVQKEDVISLVVEGTCYYDVEPEDDSWIRVQVEKGDLIVIPKGLSHRFTTTPQNFVKIQRFFSRKVEGNQG
What is the function of this protein?
Probable inactive acireductone dioxygenase.
What are the official names of this protein?
Probable inactive acireductone dioxygenase 1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL18_ANAD2
Sequence: MAKHVTTREKRRARIRRKISGTELRPRLTIYKSLKHMYAQLVDDVAGKTLVSVATTSKSLKGELGDEDKTAAAKKVGEALAKAAKAKGIEQVVFDRNGFDYHGRVEAVAAAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LYSC_MIOTA
Sequence: MKAVIILGLVLLSVTVQGKIFERCELARTLKRLGLDGYRGISLANWVCLAKWESDYNTQATNYNPGDQSTDYGIFQINSHYWCNNGKTPGAVNACHISCNALLQDNIADAVTCAKRVVRDPQGIRAWVAWRNHCHNRDVSQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDA_STRA5
Sequence: MTFKPFLNPEDIAVIQTEEKNSDKKQKRTPEQIEAIYTFGNNVLVSASAGSGKTFVMVERILDKLLRGVPIDSLFISTFTVKAAGELKERLEKKINESLKSAESDDLKQFLTQQLVGIQTADIGTMDAFTQKIVNQYGYTLGISPIFRILQDKNEQDVIKNEVYADLFSDYMTGKNAASFIKLVKNFSGNRKDSKAFREMVYKVYAFSQSTDNPKRWMQTVFLKGAQTYTDFEAIPDQEVSSLLNVMQTTANQLRDLTDQEDYKQLTAKGVPTANYKKHLKIIENLVHWSQDFNLLYGKKGLTNLARDITNVIPSGNDVTVAGVKYPIFKQLHNRIVGLKHLEVIFKYQGESLFLLELLQSFVLDFSEQYLQEKIQENAFEFSDIAHFAIQILEENHDIRQLYQDKYHEVMVDEYQDNNHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKYKAYQDNPSQGKLIILKENFRSQSEVLDSTNSVFTHLMDEEVGDILYDESHQLKAGSPRQQERHPNNKTQVLLLDTDEDDIDDSDSQQYDISPAEAKLVAKEIIRLHKEENVPFQDITLLVSSRTRNDGILQTFDRYGIPLVTDGGEQNYLKSVEVMVMLDTLRSIDNPLNDYALVALLRSPMFGFNEDDLTRIAIQDVKMAFYHKVKLSYHKEGHHSDLITPELSSKIDHFMKTFQTWRDFAKWHSLYDLIWKIYNDRFYYDYVGALPKAEQRQANLYALALRANQFEKTGFKGLSRFIRMIDKVLENENDLADVEVALPQNAVNLMTIHKSKGLEFKYVFILNIDKKFSMVDITSPLILSRNQGIGIKYVADMRHELEEEILPAVKVSMETLPYQLNKRELRLATLSEQMRLLYVAMTRAEKKLYLVGKASQTKWADHYDLVSENNHLPLASRETFVTFQDWLLAVHETYKKQELFYDINFVSLEELTDHHIGMVNPSLPFNPDNKVENRQSEDIVRAISVLESVEQINQTYKAAIELPTVRTPSQVKKIYEPILDIEGVDVMETITKTSVDFKLPDFSTSKKQDPAALGSAVHELMQRIEMSSHVKMEDIQKALTEVNAETSVKAAIQIEKINYFFQETSLGKYIQEEVEHLHREAPFAMLKEDPESGEKFVVRGIIDGYLLLENRIILFDYKTDKFVNPLELKERYQGQMALYAEALKKSYEIEKIDKYLILLGGKQLEVVKMD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: VG32_ICHVA
Sequence: MRGATTDDSITSSVRALPAVVPGSGLFLPMVLHVSSLLSLDQLMGSKSDDRPRLIGIGVSVTRVTPDPTRPAMAHTPSVFLGTRSDLIMFSPHNLKNSSVLQPGNDLSSFLLSFSSSVPRNPDPNFSASIAIVS
What are the official names of this protein?
Uncharacterized protein ORF32.
Protein: DCOR_MOUSE
Sequence: MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFPPEVEEQDDGTLPMSCAQESGMDRHPAACASARINV
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: PDLI2_RAT
Sequence: MALTVNVVGPAPWGFRISGGRDFHTPIIVTKVTERGKAEAADLRPGDIIVAINGESAESMLHAEAQSKIRQSASPLRLQLDRSQTASPGQINGEGSLDMLATRFQGSLRTHHNSQSSQRSACFSPASLSPRPDSPFSTPPPTSPIALSGENVIGCSFQSLTHSPGLAATHHLTYPGQPTSQQAGHSSPSDSTVRVLLHSPGRPSSPRLSSLDLEEDSEVFKMLQENRQGRAAPRQSSSFRLLQEALEAEERGGTPAFVPSSLSPKASLPTSRALATPPKLHTCEKCSVNISNQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGNELYCEKHARQRYSMPGTLSSQA
What is the function of this protein?
Probable adapter protein located at the actin cytoskeleton that promotes cell attachment.  Necessary for the migratory capacity of epithelial cells.  Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth.  May contribute to tumor cell migratory capacity (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes at the cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).
Protein: DXR_FERNB
Sequence: MEEKTVVILGATGSIGTQSVDVISKLKNYKLVGISFGKNRNLAEEIVQRFDVKVYHGGVELSVGRRVDSIGALLELTKPDITICAIPGFEGVKATIEALKYTRRIALATKESMVCAGKFVKELAKKNNVEIVPVDSEHSAIFQIYEPHIDHIVITASGGAVRDLPLDKIAGLTPEEVLKHPTWNMGGRITVDSATMVNKFFEVVEAHELFDLPYEKIEVYINPSSFIHGMVFLKDGTIKIHAGKPDMRVPIAYSLTYPSREYTSYVAQVDEFDMRLLPVEKARYPLFFFGLEIAKSGGLAERIAFNSADEIAVQYFLEKKILFGKIEKIVTKTVEEVQKRAITVNSLEDVYKVDELSRKITEEVLYDCIN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ATPB_RHOP5
Sequence: MATPANQNGRITQVIGAVVDVQFEGHLPAILNAIETKNGNNRLVLEVAQHLGESTVRTIAMDTTEGLVRGQEVTDTGSPIMVPVGLGTLGRIMNVIGEPVDEQGPVANEGLRPIHAEAPLYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESGVNKKGGGEGSKCALVYGQMNEPPGARARVALSGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTHKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLNRAISEKGIYPAVDPLDSTSRMLSPLIVGEEHYQTARMVQQVLQKYKSLQDIIAILGMDELSEEDKIAVARARKIERFLSQPFFVAEIFTGSPGKFVDLADTIKGFRAICEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UP03_LONON
Sequence: YEYSVYREIIGSGHIIAR
What are the official names of this protein?
Unknown protein 3.
Protein: PA2HA_BUNFA
Sequence: NMVQFKSMVQCTSTRPWLDYVDYGCNCDIGGTGTPLDELDRCCQTHANCYTEARKFPECAPYYKTYSYTCSGGTITCNADNDECAASVCNCDRTAALCFAGAPYNQNNFDVDLETRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) homolog that lacks both catalytic and neurotoxicity activities.
What are the official names of this protein?
Acidic phospholipase A2 homolog, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. A49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_NITEU
Sequence: MIESDRIITASPFSSQEEVIERALRPVQLDDYVGQEKIREQLKIFIEAARLRQEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLETNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGAAARSVKIDLPSFTLVGATTRAGMLTNPLRDRFGIVSRLEFYTADELGKIVTRSAGLLNVDVTADGAREIACRSRGTPRIANRLLRRVRDFAEVRANGRIDRPVADAALQMLDVDATGLDVLDRKLLLAVLEKFGGGPVGVDNLAAAINEERDTIEEVLEPYLIQQGFLQRTPRGRMATTMAYQHFDIIPSHQTTVPSLFDPD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IL1RA_TURTR
Sequence: MEVCRCHHGYLISLLLFLFHSETACYPLGKRPCEMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNTKLEEKIDVVPIEPHAMFLGIHGGKLCLACVKSGDEIKLGLEPVNITDLNSSKEEDKRFAFIRSDSGPTTSFESAACPGWFLCTALETDQPVGLTNTPQDAVQVTKFYFQQDQ
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_SALG2
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL10_HYPNA
Sequence: MDKAGKSAALENLKGVFEGAGVVVVTHYAGLTVAEMTKLRGLLRKDGAHFKVVKNRLAKIALGGVGGDKAQDLFQGPVAIAYSPDPVAAAKAADEFSRENSKLVIIGAVMGEQVLDAKGVEALAKLPSLDQLRGKIIGVIQAPATKVAGVIQAPASQLARVVSAYASKDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL14E_METVS
Sequence: MAAIEVGRVCIKTLGREAGNVCVIVEVLDKNYIVVDGNVKRRRCNVKHVEPTDKKVELEKGASTEEVKLSLDAAGLL
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: CYSN_FRATN
Sequence: MSHKSDLIATNIQKYLQQHQQKELLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLASIVADSKKVGTQGDRLDLALLVDGLQSEREQGITIDVAYRYFSTDKRKFIIADTPGHEQYTRNMATGASNCDLAIILIDARKGLQTQTRRHSFICSLLGIKHVIVAVNKMDTVGYSQQIYKSIQDEYLKLAGSLQIPDIRFVPISALDGDNVVSKSTKMPWFRGSPLMHYLETIKIDYAHTDEFRFPVQLVCRPNSEFRGFQGTVVSGSAKIGDTIRVMPSGKITTIKSILSFDGELNEAEAGQSITITTYDEIDISRGDMIVHKDAISHVSSMLRANIVWMSEQPLIEYKDYYIKFLTKQVIGSVNKFNYKTDINTLKEVACGTLELNEIATVELNLSEPVCFDSYQKNRTTGAFIIIDRLTNVTAGAGMVIKPLAANDKKDSTNDYSEFELELNALIRKHFPHWDAKNLRE
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: SP5G_FUSNN
Sequence: MKVTNVKIKKVDGDKFDRLRAYVDVTLDDCLVIHGLKLMQGEQGMFVAMPSRKMRNEEFKDIVHPICPELRNDITKVVQEKYFALDQEQEAVI
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: SYP_KORVE
Sequence: MHRWSKLFIPTLREAPADAEVASHKFLVRAGYIRQLAAGIYSYLFLGNRSMNKIIGIVREEMDKIGQEYYLPALNPREIWEASGRWAVMGDNMFRLKDRKGAELCLGMTHEEIMTEIARKELRSYKQLPQIWYQIQTKFRDEPRPRSGLLRVRQFIMKDSYSFDIDAAGLDISYQKHHDAYCRIFDRCGLKYVVVHADSGAMGGSGSQEFMVYTDAGEDLVASCANCSYAANVEKATSKLEAIEDLVATADTPELVHTPGQKTIEQVAAYLGVSPKNKIKTLAYMMAAPKGAKDGREQALVVLLRGDHMLNEAKLGAAIKGREVRPMTEEEIQDLFHSPAGYLGPLNVEWAKTSEDTEKPLLLLDEALVSRKNLIAGANKEEYHVRNLTPGESFQFTGSADLRMVAEGEPCPNCGHALKVGKTVEIGHIFKLGYKYTDAMGARVLDKDGKEVMPIMGSYGIGMERILTASVEQSNDDNGFWLPAQIAPFEVVVTPTNVSDEKLAKGAEEIAAKLEAAGFDVILDDRDERPGVKFKDADLVGIPVRINVGKKFVEGKVEVIHRSTRESLDATIPEIVEKIAAWLKPSA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_MYCGE
Sequence: MPIKLAQTNKEIKTTFNPFWSAAVVNEKNNWKNFKKFSAIFIKVIKVFIFIFLTIVGLWGCTQTLAQPWTGTNQVLGSGLEIGYKFGTTGDYRYDLISNNFGPYFTFSDYTLAYGPFYGWFVWPAAQIVLPIMYATRVPLGSGVELGFNMILSLIVLLLLVRLITIVITLNSTLALEKMNEVQGKLAEINAKYKGAIDLQSKRNRQLEIMSLYKKHNIKSSAAFVQVFVTLPIFLIIYRIVTTLRPIKAIILFNFWDLSKVPLTEIFSNFTTTGWPFIIFLVIVLPVQFLSQKLPQVWASKRNENAKAHSQKSIEQLNKTKKMQLIFYFVFAAITAFSAAGVGVYWFLNALFTLLQSYLTHVFIVKRREKRKQNYSKLDLILERE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.