PharMolix/UniProtQA huggingface dataset:
Protein: TIM14_ASPFU
Sequence: MASTFAIGLGVATAAFLGRAGYVALRRYQGGINAMGKAFYKGGFEPRMTRREAALILELPERTLNKEKVRKKHRQLMLLNHPDRGGSPYLATKINEAKEFLDKHI
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim14, Presequence translocated-associated motor subunit pam18.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HBA2_COTGO
Sequence: MSLSTKDKDTVTAFWGKVSCKAGDIGTDALSRMLVVYPQTKTYFSHWKELGPGSPPVQKHGMTVMKGVGEAVAKIDDLTAGLLNLSELHAFTLRVDPANFKILSHNILVVFAIMFPHDFTPEVHVSMDKFLAALARALSEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL14_PSYIN
Sequence: MIQMQSVLDVADNSGARRVMCIKVLGGSHRRYAAIGDIIKVTVKEAIPRGKVKKGDVHSAVVVRTRKGVRRPDGAVIRFDRNAAVMLNANNQPIGTRIFGPVTRELRNEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: OPUAC_BACSU
Sequence: MLKKIIGIGVSAMLALSLAACGSENDENASAAEQVNKTIIGIDPGSGIMSLTDKAMKDYDLNDWTLISASSAAMTATLKKSYDRKKPIIITGWTPHWMFSRYKLKYLDDPKQSYGSAEEIHTITRKGFSKEQPNAAKLLSQFKWTQDEMGEIMIKVEEGEKPAKVAAEYVNKHKDQIAEWTKGVQKVKGDKINLAYVAWDSEIASTNVIGKVLEDLGYEVTLTQVEAGPMWTAIATGSADASLSAWLPNTHKAYAAKYKGKYDDIGTSMTGVKMGLVVPQYMKNVNSIEDLKK
What is the function of this protein?
Involved in a multicomponent binding-protein-dependent transport system for glycine betaine.
What are the official names of this protein?
Glycine betaine-binding protein OpuAC.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane raft; Lipid-anchor. Note=Present in detergent- resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: MOC2B_HUMAN
Sequence: MSSLEISSSCFSLETKLPLSPPLVEDSAFEPSRKDMDEVEEKSKDVINFTAEKLSVDEVSQLVISPLCGAISLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRKICSDIRQKWPVKHIAVFHRLGLVPVSEASIIIAVSSAHRAASLEAVSYAIDTLKAKVPIWKKEIYEESSTWKGNKECFWASNS
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B, Molybdopterin-synthase large subunit, MPT synthase large subunit.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RR18_OENBI
Sequence: MDKSKRLFLKSKRSFRRRLPPIQSGDRIDYRNISLISRFISQQGKILSRRVNRLTLKQQRLITIAIKQARILSLLPFRPKAQRFKRSQSTARTVGLRTRNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PG153_VAR67
Sequence: MVNIINLWNGIVPMVQDVNVASITAFKSMIDETWDKKIEANTCISRKHRNIIHEVIRDFMKAYPKMDENRKSPLGAPMQWLTQYYILKNEYYKTMLAYDNESLNTKFKTLNIYMITNVGQYILYIVFCIISGKNHNGTPYIYDSEITSNNKNLINDRIKYACKQILHGQLTMALRIRNKFMFIGSPMYLWFNVNGSHVYHEIYDGNVGFHNKEIGRLLYAFMYYLSISDRFLNDFALLKFTYLGESWTFSLSVPEYILYGLGYSVFDTIEKFSNDAILVYIKTNNRNGYDYVEFNKKGIVKVTETKPDNDKRIHAIRLINNSTDVQHIHFGFRNMVIIDNECANIQSSVENATDTGHHQDSKINIKDDDVDDDDYNPKPTPIPEPYPRPPFPRHEYYKRPKLLHVEEPDPVKKDADRIRLDNHILNTLDHNLNSIGHYCCDTAAVDRLEHHIETLGQYAVILARKINMQSLLFPWLLPTVHPHAIDGSIPPHGRSTIL
What is the function of this protein?
Envelop protein that mediates acid-dependent endocytosis into host cells.  Plays an important role in endocytic entry of the virus by acting as an acid-sensitive membrane fusion suppressor.  Low pH in host endosomes triggers conformational changes to allow de-repression of viral fusion complex activity and membrane fusion within vesicles.  Plays also a role in bridging the mature virion with structural protein OPG152.
What are the official names of this protein?
Envelop protein OPG153.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG153 protein family.
Protein: YGFB_ESCF3
Sequence: MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: EX7S_STRP8
Sequence: MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKELQKTLQAAEKTLVKVMQADGTEVDMDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_FRATN
Sequence: MSNISAKLVKELRERTGAGMMECKKALVAAAGDIEKAAEEMRISGQAKADKKASRVAAEGVIEVYAADGRAILLEINSETDFVARDETFKKFAQEAVKAAHAANAKTIEEVLAAKTSNGETVEEARKSLIAKIGENIQVRRVKTVEAETLGAYIHGSKIGVVAALEGGDEDLAKDVAMHVAAANPMVVSGDQVPADVVAKEKEIFTAQAKESGKPAEIIEKMIVGRIRKFLDEVALLGQDFVKDPAIKVEKLVKDKGAKVVNFIRLDVGEGIEKKEEDFAAEVMSQIKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKA1_ARATH
Sequence: MEGNQAGSSLDSLIASFNKRIGELQELVIARNMYPASTIPDLSAIDTALSSMELQVQSIKDRLREETEAIPKAKKLIEASLKQQGKLQKMSIYAPSHFPDKATMLNSDLNRCLLQENAKQYEQHSTLSSLKFDEEAAVLPKEKKGRGSPPLWYITVEELNSLSSYMRGRLTLEKVNAAINDMASYAEANAHLIAASKQKLAENLWEKALKLRDIVTEQAVKGKHFFLETDMKGPSLKLDNTGKAILTVLRHLGRISETRIGQNRVIILMKPH
What are the official names of this protein?
Spindle and kinetochore-associated protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SKA1 family.
Protein: YT23_STRFR
Sequence: MAIDRLIARREVHLREKTLWRMLYETAGRSEEILGVNIEDLDFAGRRCPAKAKGAKSKSRRRGQVREDFVLETLYWDAGTARLLPRLLKGRTRGPVFVTHRRPGPGKVVSPRDICPDTGFARLSYGQARALLDHHTAVRGVGTGWDLHEYRHSALTHLGEQGASLLMLMAKSRHKKPENVRRYFKPSPEAIAELTSLLAPGNSSR
What are the official names of this protein?
Uncharacterized 23.1 kDa protein in transposon Tn4556.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: NLGN1_RAT
Sequence: MALPRCMWPNYVWRAMMACVVHRGSGAPLTLCLLGCLLQTFHVLSQKLDDVDPLVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHAPEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.  Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins.  May promote the initial formation of synapses, but is not essential for this.  In vitro, triggers the de novo formation of presynaptic structures.  May be involved in specification of excitatory synapses.  Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep (By similarity).  The protein is involved in nervous system development.
What are the official names of this protein?
Neuroligin-1, Neuroligin I.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density. Synaptic cleft. Synaptic cell membrane. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1.
Protein: GPDA_CERS4
Sequence: MIGILGAGAFGTALAVTLGREQPVTLWARGGTPRLAVDLPEQVQLTADFGEALAGTVLLAVPMQALGGLLRAEAARLQGRALVACCKGVDLATGLGPTGLIAEACPGSPAAILTGPSFAADIARGLPTALTLATQDEAAGEALQRQLSTAALRLYRTTDTVGAELGGALKNVIAIAAGVVIGAGLGQSARAALMTRGYAEMQRLALALGARPETLAGLSGLGDLVLTCTSDQSRNFRYGQALGAGAAFDGSVTVEGRATARAVVDLAVRHGIDMPIAAMVDALVEGRVTLPQAIQSLLSRPLKQE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MARN8
Sequence: MAKLSKRQKLIREKVDSTRAYSVDEAVALLAELGQNVKFKESVDVAVNLGVDARKSDQVVRSSTVLPHGTGKTVRVAVFTQGANAEKATAAGADVVGMDDLADEVKKGNMDFDVVIATPDAMRVVGQLGQILGPRGLMPNPKVGTVTADVETAVKNAKAGQVRYRTDKNGIIHAPLGNVEFSAQNIKENLEALVADLKKAKPASSKGVYLKKITISSTMGPGLTIDQGTLSI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: UB2D2_BOVIN
Sequence: MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.  Mediates the selective degradation of short-lived and abnormal proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6.  Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection.  Essential for viral activation of IRF3.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D2, (E3-independent) E2 ubiquitin-conjugating enzyme D2, E2 ubiquitin-conjugating enzyme D2, Ubiquitin carrier protein D2, Ubiquitin-protein ligase D2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: KDPB_YERPS
Sequence: MTHKQRAIFEPALVRTALLDAVKKLDPRVQWRNPVMFVVYLGSWLTTLIWLAILSGHTTGSAMFTGSIALWLWFTVLFANMAEALAEGRSKAQAASLRGVKKTSWAKKLSEARVDAPQEKVSADSLRKGDLVLIEAGDTVPCDGEVLEGGASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWLVVECRVNPGETFLDRMIAMVEGAKRRKTPNEVALTILLVALTIVFLLATATLYPFSVFSVEASQAGSPVTITVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFLPAPGVTEQQLADAAQLSSLADETPEGRSIVVLAKQRFNLRERDLHSLNATFIPFSAQTRMSGVNVQERMIRKGAVDAIRRHVESNQGHFPPAVDDLVASVARTGGTPLVVAEGSRVLGVVALKDIVKGGIKERFAELRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMQLHSPSSAILSAVIFNALVIVFLIPLALKGVSYKAMSAAALLRRNLWIYGLGGLLVPFVGIKLIDLLLTALNMG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5147_FRASN
Sequence: MSGHSKWATTKHKKAVVDARRGKLFAKLVKTVEVAAKTGGGDPAGNPTLADAIAKAKSQSVPNDNIERAIKRGSGELAGGVSYESVTYEAYGPNGVAVLVECLTDNRNRAASDVRVAITRNGGTPADPGSVSYLFNRKGVVLIDKTPTLTEDDILLAVLDAGAEEVNDVGEAFEVVSEATDLHAVRVAAAEADLTVASADISWLPSVSVPLDAEPARKVLKLVEALEDLDDVQNVWFNADISDDVMELVSS
What are the official names of this protein?
Probable transcriptional regulatory protein Franean1_5147.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_EXISA
Sequence: MAIKKFKPTTNGRRNMTSLDFAEITTNRPEKSLTEKLSKKGGRNNQGRLTVRHQGGGHKRKYRIIDFKRNKDGVAGRVATIEYDPNRSANIALINYVDGEKRYILAPKGIKVGMEIMSGPEADIKVGNALPLVNIPVGTTIHNIELKPGKGGQLVRAAGASAQIQGRDGKYVIVRLQSGESRLFLGTCRATIGSVGNEEHELVNIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRAPIGRSGPLTPWGKPALGLKTRKKNKSSDMYILRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: REL1_MOUSE
Sequence: MSSRFLLQLLGFWLLLSQPCRTRVSEEWMDGFIRMCGREYARELIKICGASVGRLALSQEEPALLARQATEVVPSFINKDAEPFDTTLKCLPNLSEELKAVLSEAQASLPELQHAPVLSDSVVSLEGFKKTLHDRLGEAEDGSPPGLKYLQSDTHSRKKRESGGLMSQQCCHVGCSRRSIAKLYC
What is the function of this protein?
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
What are the official names of this protein?
Prorelaxin 1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTIP_BOVIN
Sequence: MNLSGSSCGSPSSADVSNDFKDLWTKLKEYHDKETQGLQVKVTKLKKERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNEKNTLQEENKKLSEQLQQKIENDQPHKATDLESEEDVIPDSPITTFSFSGTNRLRRKENLRVRYIEQTHAKLEHSGCAHELRTVPKSSAHPQHKPKESEILVADTCDQSQAPVAKPHGKSSYTPDNLATVVAETLGLCVQEESESRGPQSPLGDELYHCLEGDHKKQAFEECRRNSEDNLRFSDSKTPFQEELTTRVSSPVFGAPSNVKSSLGLNTSLSPSLLETGKKTHLKTVPLSNTSAPGPEKPRSKSEDGTLITHHHLGTEVNKIPSQSSSNKQMLINKNTSEPISEQGNIGHSKDTDRDKHVVPLKSLGGRTKRKKIEEESEDEVICPQASFDKENAFPFPLDSHSSMNGDYVMDKPLDLSDRFSAIQRQEKSQGCENSKIRFRQVTLYEALKPIPRDSSSSRKALSGSCGLTKDSPEEPCLQESLFQSLSKSPDNKTLLQIKEENPVFKIPLRPRESFETENLFDDTKGAGSHEPIKIKTRSVRGACEVASVLQLNPCRIAKTKSLQNNQDVSFENIQWSIDPGADLSQYKMGVTVDDTKDGSQSRLAGETVDMDCTLVSETMLLKLKKQEQKGEESPNGERKMNDSLEDMFDRTTHEEYESCLAESFPQVADEEKELSTTTKKPNISW
What is the function of this protein?
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway.  HR is restricted to S and G2 phases of the cell cycle and preferentially repairs DSBs resulting from replication fork collapse.  Key determinant of DSB repair pathway choice, as it commits cells to HR by preventing classical non-homologous end-joining (NHEJ).  Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA.  Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage (By similarity).  During immunoglobulin heavy chain class-switch recombination, promotes microhomology-mediated alternative end joining (A-NHEJ) and plays an essential role in chromosomal translocations (By similarity).
What are the official names of this protein?
DNA endonuclease RBBP8, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2.
What is the protein family that this protein belongs to?
Belongs to the COM1/SAE2/CtIP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with sites of DNA damage in S/G2 phase. Ubiquitinated RBBP8 binds to chromatin following DNA damage.
Protein: DDL_VESOH
Sequence: MIAILMGGNSAERAISLKSGEAIYQTLNNQNIDCFTFDWYGDNLSEFWQQEFDQVFIILHGRGGEDGYIQKQLENRGICYTGSDSNASHNSMDKARTKIIWEQHSLTLAPSIIANIDQPINPINFPLPWAVKPTLEGSSIGISKVDNQMQLNDALMLAWQYAPYALIEQWIKGDEYTVAILGDKALPVVRIITDQNFYDYESKYHSNKTQYLCPCNLSLTQEKALQAIALKAFFAINAKGWGRVDFIINQHNKPYLLEINTVPGMTSHSLVPMAAKAIGISFNKLVTSIINEI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGZ_HAES1
Sequence: MSILLIDLSSQELRQEEIELLEHPLVAGLILFSRNFYDIEQIRHLIRSVRQKVKKPLLITVDQEGGRVQRFRQGFTQLPAMQSFACLLSDPQEQQEMAWRAGWQMAAEMTALDIDLSFAPVLDLGHQCKAIGDRSFHYEEKKLIELAEKFIQGMRQIGMSATGKHFPGHGHVLADSHLETPYDDRAKELIFAQDIRPFQSLIKQGLLDAVMPAHVIYTQCDNQPASGSSYWLKEVLRQQLGFQGAIFSDDLGMKGAGFMGDFVARCTQSLQAGCDLLLLCNEPEAVVQVLDRFKPQESQNKRIIRQTRLNKLFKKQRIDWQTLRNQRDWLENHKKLTALQQDWLAYKGYDN
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_SYMTH
Sequence: MALYNVDGIVIRVRNFQDADKIVVLLTREEGKVEAVARGARRPRNRFAAATQLFSHVRAQLFSGRSLDTLSQVEIVESFRQLREDLVRMAYATYACELVDALLPERQRQEAPYLLLLTSLHLWGEPDRDPEPLLRAFELKLLSMLGFRPSLAACVGCGSEAVQQNGGVRFAPVLGGVLCPQCTDEGEGALRLSLGALETMKRLLDGDIRRAHMVRLSGELAAEIDRALSAYILARTERRLKSKEFLDTLRSAR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GATC_BACMK
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: 14KL_BRUA4
Sequence: MNIFKQTCVGAFAVIFGATSIAPTMAAPLNLERPVINHNVEQVRDHRRPPRHYNGHRPHRPGYWNGHRGYRHYRHGYRRYNDGWWYPLAAFGAGAIIGGAVSQPRPVYRAPRMSNAHVQWCYNRYKSYRSSDNTFQPYNGPRRQCYSPYSR
What is the function of this protein?
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose.  Essential for virulence.  May be involved in LPS biosynthesis or polysaccharide transport (By similarity).
What are the official names of this protein?
Lectin-like protein BA14k.
What is the protein family that this protein belongs to?
Belongs to the BA14k family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL22_CITK8
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y1443_HALOH
Sequence: MLNPYEIMETIRMIEEEKLDIRTITMGISLRDCAHPSGEVARKNIYDKILRYAGNLVEVARDIELEYGIPIINKRIAVTPISLVAESSSEEDFIKFAETLDKAAGEVGVDFIGGFSALVHKGFTTGDKKLINSIPRALANTERVCSSINVATTRAGINMEAVSRMGKIIKKTARETRDKGGLGCAKLVVFANVPEDNPFMAGAFHGIGEPECVINVGISGPGAVKAALKKVKGQKFDTVAETIKKTAFKITRAGQLVAREASKRLNVPFGIVDLSLAPTPAVGDSVAEILEEMGLESCGAPGTTAALALLNDAVKKGGTMASSHVGGLSGAFIPVSEDAGMIKAVKRGSLNLEKLEAMTCVCSVGLDMIAVPGSTKADTISAVIADEVAIGVINNKTTAVRIIPVPGKDVGDEVEFGGLLGTAPVMDVSKFSSSAFIGRGGRIPAPIHSLKN
What are the official names of this protein?
UPF0210 protein Hore_14430.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: DTD_YERPS
Sequence: MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.