PharMolix/UniProtQA huggingface dataset:
Protein: HSCA_HAEDU
Sequence: MALLQIAEPGQTAAPHQLRLAVGIDLGTTNSLVASVRSRQVQVLLDDKESALIPSVVHYTETSKMVGVTAFEQASYDPQNTIISAKRLIGRSLMDVQTRYPNLPYQFQASENGLPLIHTRQGYKSPIEVSADILSHLNHLAEQRLAGELSGVVITVPAYFDDAQRQSTKDAARLVGLNVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSKGVFEVLATGGDTALGGDDFDHLLADWIATQAAVQPKNATEQRQLLTLATQTKIALSQADETPLHFANWTGNITQAQFNQLIQPLVKRSLVACRRALKDASVDIEEVCQVVMVGGSTRVPFVREAVGEFFAKKPLTSIDPDKVVALGAAIQADILVGNKPDNEMLLLDVVPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTAKDGQTAMSVHVLQGERELVDDCRSLARFTLRGIPPMVAGAATIRVTYQVDADGLLSVTAMEKSTKVQASIQIKPSYGLTDEEVTQMIKSSMSNAKADMEARQLAEQRVEADRAIEMVMAALQKDGKAVLSVAEFNAIEVEMQKLIELKAGTDRIAIQQSIKDLDLATQAFAAKRMNLSIQKALAGKAVDEII
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: KHSE_MYCTU
Sequence: MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAVRWSPTVRVPG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_KLEP3
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDEQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKELFLNAGKRIVELTKRYYEQDDASALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMVTQDDAVKKMFRAGPAGIRTTQAFSQDCRWDTLDDDRAEGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDEAVDAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTTFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGNIAIIEDGDMIAIDIPNRGIQLQLSDAEIAARREAQEARGDKAWTPKDRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CLCA1_HORSE
Sequence: MGSFKSSVFILVLHLLEGALSNSLIHLNNNGYEGIVIAIDPNVPEDETLIQQIKDMVTQASPYLFEATEKRFYFKNVAILVPENWKTKPEYERPKLETYKNADVLVAEPNPPGNDQPYTEQMGKCGEKGERIYFTPDFLAGKRLDEYGPQGRVFVHEWAHLRWGLFNEYNDDQKFYLSNKEIKPVKCSADIAGKNVVNHCQGGSCATKPCRRDRVTGLYAQECEFIPDEQQTEKASIMFSQSIDSVVEFCTEENHNREAPNMQNQRCNLRSTWEVIRDSEDFKKTTPMTAQPPQPTFSLLQIGQRIVCLVLDKSGSMAIGDRLKRLTQAGKLFLLQTVEQGSWVGMVTFDSAAYVQSALRQIKGGTDRDALTKSLPTVASGGTSICSGLRSAFTVIRKKYKTDGSEIVLLTDGEDNTISSCFNEVKQSGAIIHTVALGPSAAAELEELSKMTGGLQTYASDQAQNNGLIDAFGALSSGNGAVSQHSIQLVSRGSTLQNSQWMNGTVIVDSTVGNDTLFLITWTSQPPQILLWDPSGKKQDGFVVDTNTKMAYLQVPGTAKVGTWTYSLQASSQTLTLTVTSRASSATLPPVTVTSKVNKDTGKFPSPVVVYAKIHQGGLPILRATVTALIESVDGKTVTLELLDNGAGADATKDDGIYSRYFTAYNTNGRYSIKVWALGGVNAARQMGISQQNGAMYRAGRMKNGEIIWNPPRPKINIDDLLSKQVPFSRTSSGGSFVASNVPNAPIPDLFPPCQITDLKAKIQGDSLINLTWTAPGDDYDHGRADRYIIRISTNILDLRDKFNDSLQVNTTDLIPKEATSEEVFVFKPENIAFENGTDLFIAIQAVDEVDLESEISNIAQVSLFLPPQTPPETPSPSLPCPDSNITSAIPGIHILKVMWKWLGELQLSVALG
What is the function of this protein?
May be involved in mediating calcium-activated chloride conductance.  May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR.  May be involved in the regulation of mucus production and/or secretion by goblet cells.  Involved in the regulation of tissue inflammation in the innate immune response.  May play a role as a tumor suppressor.  Induces MUC5AC (By similarity).
What are the official names of this protein?
Calcium-activated chloride channel regulator 1, Calcium-activated chloride channel family member 1, eCLCA1.
What is the protein family that this protein belongs to?
Belongs to the CLCR family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LNT_BORPE
Sequence: MSPAGKGPAWRQPAILAAAGAAHALSFAPDPLPAWSLAPVQVIALAVAAHASLQAPSARRALARGWLFAMFSFSLGLYWMYVSMHDYGGLAAPLAAAGVLALSAFLALFPGLACAAARWLCPPHWDASPPARARRTLYTAATWAACWAALEWLRAVVLTGFPWLNISYAHVDSPLAGWAPLLGVHGMALLAAFAAAALAGLWQSASGRIDSRQALAAGVALLLAGAGWLLGQFSWSRPEGKPLHLRLVQGNVEQSQKFDPALLETGLRRHLELASLPPRPGEPKPDMIILPETVLPVFQDQLPASVWDAWIEVARRADTRIAMGVPLHTQPDGATGHRYTNSVIGFDASTPVEQLRTGTTAMRYDKQHLVPWGEYVPPGFRWFVDMLDIPLGDFDRGAARQPSFDIAGQRIAFNICYEDLFGPELLPALQDGPDGRPGATIMANVSNLGWFGNTWALRQHLQIGRLRTMETARPMVAATNTGITAAIDARGRVAAALPADRAGVLPVAVQGMTGLTPYARFGDKPALALIGLLLIAAAARGRRPRQP
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Putative apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPH_BACAH
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDGNSKYIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: QAY_NEUTR
Sequence: MTLLALKEDRPTPKAVYNWRVYTCAAIASFASCMIGYDSAFIGTTLALPSFKKEFDFASYTPGALALLQSNIVSVYQAGAFFGSLFAFATSYFLGRRKSLIAFSVVFIIGAAIMLAADGQGRGIAPIIAGRVLAGIGVGGASNMVPIYISELAPPAVRGRLVGIYELGWQIGGLVGFWINYGVNTTMAPTRSQWLIPFAVQLIPAGLLFLGSFWIPESPRWLFANGKREEAMKVLCWMRNLEPTDRYIVEEVSYIDADLERYAREVGKGFWKPFLSLKQRKVQWRFFLGGMLFLWQNGSGINAINYYSPTVFRSIGITGTNTGFLTTGIFGVVKMVLTIVWLLWLVDLVGRRRMLFIGATGGSLCMWFIGAYIKIAGPGSTKAEDAKLTSGGIAAIFFFYLWTAFYTPSWNGTPWVINSEMFDQNTRSLGQASAAANNWFWNFIISRFTPQMFIKMEYGVYFFFASLMLLSIVFIYFFIPETKSIPLEAMDRLFEIKPVHNANKILMAELNFDRNPEREESSLDEKDRVTQTENAV
What are the official names of this protein?
Quinate permease, Quinate transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTGES_CANLF
Sequence: MPPPVLALVSGQALPAFLLCSTLLVIKMYVVAVITGQVRLRKKAFANPEDALRHGGLQYCRSDQDVDRCLRAHRNDMETIYPFLFLGFVYSFLGPDPFIAQMHFLVFFLGRMVHTVAYLGKLRAPTRSLAYTVAQLPCASMALQIVWEAACHL
What is the function of this protein?
Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway.  Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (By similarity).  Plays a key role in inflammation response, fever and pain (By similarity).  Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2.  In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (By similarity).
What are the official names of this protein?
Prostaglandin E synthase, Glutathione peroxidase PTGES, Glutathione transferase PTGES, Microsomal prostaglandin E synthase 1, MPGES-1.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm, perinuclear region. Note=Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.
Protein: ASPM_ATEGE
Sequence: TRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQAMFRRWKQRKMQLQVKATITLQRAFREWHLRKRAKEEKSAIVIQSWYRMHKQLRKYVYVRSCVVIIQKRFRCFQAQRLYKRKRESILTIQKYYRAYLKGKIERIHYLQKRAAAIQLQAAFKILKAHNLHRPIRAACVIQSYWRMRQDRVRFLNLKKNIIKLQAHVRKHQQLQKYKKIKKAAVIIQTHFQAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYVHLRATALFIQQCYHSKKLAAQKREEYMQMRESCIKLQAFVRGYLVRKQIRLQRKAVISLQSYFRMRKARQYYLKMYKAVIIIQNYYHSYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSVAAVKIQSAFRGYSKRVKYLSVLQSIIKIQRWYRAYKTLYDIRTRFLKAKAAVISLQSAYRGWKVRKQIRREHQAAMKIQSAFRMAKAQKQFRLFKTAALVIQQHLRAWIAGRKQRMEYIELRHSVLMLQSMWKGKTLRRDLQRQHTCAVIIQSYYRMHVQQKKWKIMKEAALLIQKYYRACRIGREQHCLYLETKAAVLTLQSAYRGMKVRKRIKACNTAAITIQSKYRAYKTKKKYAAYRASAIIIQRWYRGIKITNHQYKEYLNLKKTAIKIQAVYRGIRVRRHIQHMHRAATFIKAMFKMHQPRIRYHTMRKATIVIQVRYRAYHQGKMQRENYLKILKAVNILQANFRGVRVRRTLRKLRIAATLIQSNYRRYRQQTYFNKLKKITRTVQQRYRAVKERNIQFQRYNKLRHSVIYIQALFRGMKARRHLKTMHIAATLIQRRFRALMLRRRFLSLKKTAIWIQRKYRAHLRTKRHLQFLRLQNAAIKIQSSYRRWMIRKKMREMHRAAAFIQATFRMHRVHMRYHALKQASVVIQQRYQANRAAKLQRQHYLRQRYSAVILQAAFRGMKTRRHLKSMYFSAILIQSRFRSLLVRRRFISLKKAAIFIQRKYRATICAKHKLRQFLQLRKAAITIQSSYRRLMVKKKLQEMHRAAVLIQATFRMHRTHITFQTWKHASILIQQHYRTYRASKLQRENYTKQWHSAVIIQAAYRGMKARQLLREKHKAAIIIQSTYRMYRQYCLYQKLQWATKIIQEKYRADKKKHKALQHTELRKAETCVQASFQDVNIEKLIQEQHQTSIIIQKHCKAFKIKKHYLHLRAPVVSIQRRYGKLTAVHTQAVICIQSYYRGFKVRRDIQNMHLAATRIQSFYRMHRAKVHYQTKKTAIVIIQNYYRLYVRVKTERKSFLAVQKSVRTIQAAFRGMKVRQKLKNIPKEKMAAIVDQSALYCYRSKGQDEAVRSEGVIIQEWCKASCLACSQEEYHSQSRAAVTIQKAFRRMITRKLETQKCATLRIQSFLRMAVYRRRRANSVQQKRAAVTLQHYFRMWQTRKQFLLYRKAAVVLQNHYRAFLSGKHQRQVYLQIRSSVIIIQARIKGF
What is the function of this protein?
Probable role in mitotic spindle regulation and coordination of mitotic processes.  May have a preferential role in regulating neurogenesis (By similarity).
What are the official names of this protein?
Abnormal spindle-like microcephaly-associated protein homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin.
Protein: RF1_CORK4
Sequence: MATHVSAVDDIVSEYQGLEAQLADPDLHNDAARARKVGKRFSELQPIIQTNDRLNAVTDDLEAAEEMAHEDQEFAAEAERLREEKEELSDKLADLLAPRDPHDGDDIVMEVKSGAGGEEAALFAGELVRMYQRYADKHGFAIDVLDDAPTDLGGIKDITMSIRSKKPSRDGAWSVFKFEGGVHRVQRVPVTESQGRIQTSAAGVLVYPEPDEIEDVEIDDKDIRVDVYRSSGKGGQGVNTTDSAVRITHLPTGLIVTCQKERSQIQNKARAMQVLAARLQQMKEEEAEAAASADRAAQVRTMDRSERIRTYNFPENRISDHRINYKAHNLDQVLDGDLDDLFSALQSAERAERLEAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_THET8
Sequence: MRIGLFGGSFDPIHLGHLLAASQAQEVLCLDRVLFVVAARPPHKVPVAPAEARYEMTLLAVAEDPRFTVSRLELDRPGPSYTVDTLREARRLFPQDELFFITGADAYRDVLTWKEGERLPEYATLVAVARPGYPLEEAPLPVVPLFVPEVGISSTEIRRRLKEGRSVRYWVPRAVEVYIEKHGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TIN4O_HOPOC
Sequence: RTCIPIPPVCF
What is the function of this protein?
Stimulates insulin release from beta cells at a concentration of 1 uM and release of glucagon-like peptide 1 (GLP-1) from enteroendocrine cells at a concentration of 10 nM in vitro.  Reduces secretion of interferon gamma from peritoneal cells in a mouse model.  Has no inhibitory activity against Gram-positive bacterium B. megaterium Bm11 or Gram-negative bacterium E. coli ATCC 25922 at concentrations of up to 100 uM.  Has no hemolytic activity against mouse erythrocytes.
What are the official names of this protein?
Tigerinin-4O.
What are the subcellular locations of this protein?
Secreted.
Protein: TRP6_PYRAP
Sequence: APSSMGFMGMR
What are the official names of this protein?
Tachykinin-related peptide 6, TKRP-6.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1513_CORDI
Sequence: MTATHNHYLAVLGEDFVAQQYANEGYDITARNVSFSVGEIDIIATSPQGEVVFIEVKTRSSSLMDAAEAVTPTKMRKIHRAASKWLQGKPFADIRFDVVAVHVDEYGELDMTRYQGVEHGAC
What are the official names of this protein?
UPF0102 protein DIP1513.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NUOK_CERS5
Sequence: MVGLEHYLTVSAALLVIGIFGIFLNRKNVIVILMSIELMLLAVNINLVAFSSFLGDLTGQVFTLFVLTVAAAEAAIGLAILVTFFRNRGTIDVEDVNVMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AGN2_PAEDI
Sequence: MSTTSAQATAVVTGSFLSGAMISLSLMAVPVLLDTTTEPTQLFFQWRRMYHYGHQVLPTMAVATTLLYAYTASKRRRAQKPSWAVFALAGTITVSMIPFTWLCMVPTNNVLFGLEAATRLGEPSGMGIEEAQALLVKWSWLHFTRSLMPLMGAILGSLGETVWN
What is the function of this protein?
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites (PubMed:30746079).  The pathway begins with the assembly and cyclization of atrochrysone thioester by the non-reducing polyketide synthase Agnpks1 (PubMed:30746079).  The atrochrysone carboxyl ACP thioesterase AgnL7 then breaks the thioester bond and releases the atrochrysone carboxylic acid as the first enzyme-free intermediate (PubMed:30746079).  The decarboxylase AgnL1 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase AgnL2 (PubMed:30746079).  Emodin then undergoes reduction catalyzed by the oxidoreductase AgnL4 to yield the dihydroquinone tautomer which is the substrate for reduction by the short chain dehydrogenase AgnL6 reduction to produce hydroxyketone, followed by AgnL8 dehydration and likely spontaneous autoxidation to chrysophanol (PubMed:30746079).  Baeyer-Villiger oxidation by the oxidase AgnL3 leads to monodictyphenone via cleavage of the C-10/C-10a bond of chrysophanol (PubMed:30746079).  Alternative cleavage at the C-4a/C-10 bond of chrysophanol leads also to the formation some cephalone F (PubMed:30746079).  Further conversion to agnestins A and B, requires reduction to dihydro-monodictyphenone, oxidation to agnestin C probably via an epoxide, and rearrangement to either agnestin A or agnestin B directly, although agnestin A or agnestin B can also interconvert (PubMed:30746079).  Within the cluster, AgnR1 is the only unassigned oxidoreductase present which could be involved in this conversion.  However, AgnR1 seems not to be involved in this step, and thus genes involved in the proposed oxidation/reduction may be located elsewhere on the genome (PubMed:30746079).  Further agnestin A derivatives are probably formed by spontaneous decarboxylations, dehydrations and methanolysis reactions (PubMed:30746079).
What are the official names of this protein?
Anthrone oxygenase AgnL2, Agnestins biosynthesis cluster protein L2.
What is the protein family that this protein belongs to?
Belongs to the anthrone oxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FA32A_HUMAN
Sequence: MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK
What is the function of this protein?
Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis.  May also increase cell sensitivity to apoptotic stimuli.
What are the official names of this protein?
Protein FAM32A, Ovarian tumor-associated gene 12, OTAG-12.
What is the protein family that this protein belongs to?
Belongs to the FAM32 family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: KAD3_ORYSJ
Sequence: MAANLEDVPSMELMTELLRRMKCSSKPDKRVILVGPPGCGKGTQSPLIKDEFCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKTSCQKGFILDGFPRTVVQAQKLDEMLAKQGTKIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGLDDVTGEPLIQRKDDTAAVLKSRLEAFHVQTKPVIDYYTKKGIVANLHAEKPPKEVTVEVQKALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase 3, ATP-AMP transphosphorylase 3, ATP:AMP phosphotransferase, Adenylate kinase A, AK A, Adenylate monophosphate kinase 3.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIPJ_LAMBD
Sequence: MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVDGLKSVLLNSTPVLDTEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITRTITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTTSQYLASVVMGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALVGVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCLWDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKTWTYNRSNVVMPDDGAPFRYSFSALKDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLWLIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLDREITLPSSGTALISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWELKLPTLRQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGEQSGTVNGVTPPAVQHLTAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTVQFEFWFSEKQIADIRQVETSTRYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKSAFVEAVGRASDDAEGYLDFFKGKITESHLGKELLEKVELTEDNASRLEEFSKEWKDASDKWNAMWAVKIEQTKDGKHYVAGIGLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFLKRLTAPTITSGGNPPAFSLTPDGKLTAKNADISGSVNANSGTLSNVTIAENCTINGTLRAEKIVGDIVKAASAAFPRQRESSVDWPSGTRTVTVTDDHPFDRQIVVLPLTFRGSKRTVSGRTTYSMCYLKVLMNGAVIYDGAANEAVQVFSRIVDMPAGRGNVILTFTLTSTRHSADIPPYTFASDVQVMVIKKQALGISVV
What is the function of this protein?
Attaches the virion to the host receptor LamB, inducing viral DNA ejection.  During tail assembly, initiates distal tail tip assembly by interacting with gpI, gpL and gpK.  During virus entry to host cell, binds strongly to host LamB in an irreversible attachment.  The binding induces structural changes in the tail leading to viral DNA injection through LamB trimeric pore.
What are the official names of this protein?
Tip attachment protein J, Central tail fiber, Host specificity protein J.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RS8_EHRRW
Sequence: MSLSDPIANFLTSIRNGQLSMNKVVTVSYSYVIHAILQILLSEGYIDGFTEKLRSTNIKFFEVKLKYYNGVPVINRICRVSKPGKRCYCSAKGMPKFYNGLGLYIISTSKGIMSDYNARKSGVGGEILCGVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y1683_ARCFU
Sequence: MAALIDTGIFFGFYSLKDVHHMDSVAIVVHAVEGKWGRLFVTNHILDETLTLLKYKKLPADKFLEGFVESGVLNIIYTDDEVERKALEVFKARVYEKGFSYTDAISEVVAEELKLKLISYDSRFSLPTIGRDYWKSLDESERKRISAILREKGIDG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.
What are the official names of this protein?
VapC ribonuclease AF_1683, RNase AF_1683, Putative toxin AF_1683.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: RL31_SULIY
Sequence: MKEKDNFEMVINLRKIKTGKRTGRSKRAVKFVRKIVARHFNADKVVIDPLLAKSISKNGNDKVVSKVRVVVSKVGEKIYLVRLAIKSR
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: PROA_BURCH
Sequence: MDIDQYMTDLGRRARHASRAMARASTAAKNAALDAVARAIERDAQALKDANARDVARAREKGLDAAFIDRLTLSDKALNTMVEGLRQVASLADPIGEIGNLKFRPSGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNAALAKLIGEGLEAAGLPQDAVQVVATADRAAVGKLITMTEYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRADLAKALTVCDNAKTHRYGTCNTMETLLVASGIAAKLLPPLGKLYRDKQVELRVDAAARAVLADAGVGPLVDVTEEDWHTEYLAPVLAIKVVDGLDAAIEHINHYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGEGRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_RHOPT
Sequence: MDAVIAPRHEDCRDAERRAEPLPANAPLSMPVQSLLQSPQAAAVRSPAAWRRALIMVATAVLSAAGIYEMYQVLQVGGITVLEGVVLVLFAALFAWVALSFVSALAGFTVLCCGWRDDVGIMPDGSMPAVSSKIAMLLPTYNEDAPVVFARLQATRQSVDETGRGAQFDWFVLSDSTDPSVWIDEERCYAELAATHDRLYYRHRPYNTARKSGNIADWVERFGGAYDFMVILDADSVMTGDVLVRIAAAMETNSDVGLIQTLPVVVQARTLFARVQQFAGSIYGPMIAAGTAWWHGSESNYWGHNAIIRVSAFAGSAGLPTLAGRKPFGGEILSHDFVEAALMRRGGWRIHLAPTLRGSYEECPPSLLDFAARDRRWCQGNLQHGKLLTARGLHWVSRLHFLTGIGAYLTAPMWLAFLVAGILISLQAQFVRPEYFPKDFSLFPIWPAQDPVRAAWVFAGTMGLLILPKLLALLLVLIRSQTRRRFGGGLRTFGGVLLETMISALTAPVMMVFQSTAVIEILLGRDAGWQVQHRGDGAIPLREVVRRYALPTALGATMAVGAWLVSWPLLLWMTPVIVGLLLAIPVALLTTRVSRSRPLLMTTPEQIDPPAILAQVHALADRLRPANQTTDPLSALCSDRRLRELHLAALAFHPPRRRGRIDPHLATARVLIDDAESYSEAAGWLGPREIRAVLGDRETLQRLLKLSGEHAQLAVGSEPSG
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.