PharMolix/UniProtQA huggingface dataset:
Protein: Y1471_PROA2
Sequence: MPSSEHSFISVPHDALRSVRSFLAFFSKSFNRDQVLLSAGSLAFQTLLSIVPLMAVILSVLSVSPVFDSFKQYVEEFIFQNFLPASGVEVQEYLWQFISKTSSVPTIGGLSLFIIALFLISTIDHTLNRIWGVDAPRKFFQGFTLYWTVLTLGPIFIGSSLVATSYVWYNFFTQGALADVQAKTLLLLPVMNTFLAFFLLYILVPNRKVKFVHAFSGAILATLLFEFSKRWFAFYVSHVATFEHIYGALSVIPLLFFWIYLIWVVALSGAEFVYCLGVVHPERAVVREFHPLLGISAVLLVIERISAAQSSGGFLTMNTLEDLCRSVTRMQLRRITDFLLQQNIIHKTEEGSFALSADLHTLTLYDLYAILPADLVQPKDPETSDSHFGQDLSGLEQNIIQCLQHAMHQPLAAFLNTATRTL
What are the official names of this protein?
UPF0761 membrane protein Paes_1471.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H2B1K_HUMAN
Sequence: MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
What is the function of this protein?
Has broad antibacterial activity.  May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
What are the official names of this protein?
Histone H2B type 1-K, H2B K, HIRA-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: KTHY_GEOSW
Sequence: MKGRFFSFEGPDGAGKTTMITKLESFLREKGFDVLLTREPGGVRIAEEIRSIILNPKHTEMDGRTEALLYAAARRQHLLEKIIPAIKAGKIVLCDRFVDSSLAYQGFARGLGIDEILQINQFAIDGFFPSLTIYFDIDPKIGLERIQKNKQREINRLDMESLSFHYKVREGYLKIAERFSDRIIVIDASKPVDEVFAMTIAAVMDQIEGR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GB_VZVO
Sequence: MSPCGYYSKWRNRDRPEYRRNLRFRRFFSSIHPNAAAGSGFNGPGVFITSVTGVWLCFLCIFSMFVTAVVSVSPSSFYESLQVEPTQSEDITRSAHLGDGDEIREAIHKSQDAETKPTFYVCPPPTGSTIVRLEPPRTCPDYHLGKNFTEGIAVVYKENIAAYKFKATVYYKDVIVSTAWAGSSYTQITNRYADRVPIPVSEITDTIDKFGKCSSKATYVRNNHKVEAFNEDKNPQDMPLIASKYNSVGSKAWHTTNDTYMVAGTPGTYRTGTSVNCIIEEVEARSIFPYDSFGLSTGDIIYMSPFFGLRDGAYREHSNYAMDRFHQFEGYRQRDLDTRALLEPAARNFLVTPHLTVGWNWKPKRTEVCSLVKWREVEDVVRDEYAHNFRFTMKTLSTTFISETNEFNLNQIHLSQCVKEEARAIINRIYTTRYNSSHVRTGDIQTYLARGGFVVVFQPLLSNSLARLYLQELVRENTNHSPQKHPTRNTRSRRSVPVELRANRTITTTSSVEFAMLQFTYDHIQEHVNEMLARISSSWCQLQNRERALWSGLFPINPSALASTILDQRVKARILGDVISVSNCPELGSDTRIILQNSMRVSGSTTRCYSRPLISIVSLNGSGTVEGQLGTDNELIMSRDLLEPCVANHKRYFLFGHHYVYYEDYRYVREIAVHDVGMISTYVDLNLTLLKDREFMPLQVYTRDELRDTGLLDYSEIQRRNQMHSLRFYDIDKVVQYDSGTAIMQGMAQFFQGLGTAGQAVGHVVLGATGALLSTVHGFTTFLSNPFGALAVGLLVLAGLVAAFFAYRYVLKLKTSPMKALYPLTTKGLKQLPEGMDPFAEKPNATDTPIEEIGDSQNTEPSVNSGFDPDKFREAQEMIKYMTLVSAAERQESKARKKNKTSALLTSRLTGLALRNRRGYSRVRTENVTGV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans- Golgi network (TGN).
Protein: MSRAB_STRPQ
Sequence: MIYLAEGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: DFB15_MOUSE
Sequence: MKTFLFLFAVLFFLDPAKNAFFDEKCSRVNGRCTASCLKNEELVALCQKNLKCCVTVQPCGKSKSNQSDEGSGHMGTWG
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 15, BD-15, mBD-15, Defensin, beta 15.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_RICPR
Sequence: MLPSIVKHATSHKINPLKKHGQNFIFDSSLCDKIIRASNVLENSNVIEIGPGIGGLTRSILQKNPKSLTVIEIDERCIPLLNEIQEYYPNLNIIKQDVLKINLTDLIYDKVTVISNLPYHIGTELVIRLLKEVKLITNMTLMLQKEVVERICAIPSTKAYGRLSVICQILAKVEKCFNVAPTAFYPHPKVYSAIVKIIPLENPPSIALINKVEQITKLVFAGRRKMIKSSLRNLIPNIHEVLTQLKINCNDRAENLTPKDYLRIAMKL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMK1_ARATH
Sequence: MKKRRTFLLFSFTFLLLLSLSKADSDGDLSAMLSLKKSLNPPSSFGWSDPDPCKWTHIVCTGTKRVTRIQIGHSGLQGTLSPDLRNLSELERLELQWNNISGPVPSLSGLASLQVLMLSNNNFDSIPSDVFQGLTSLQSVEIDNNPFKSWEIPESLRNASALQNFSANSANVSGSLPGFLGPDEFPGLSILHLAFNNLEGELPMSLAGSQVQSLWLNGQKLTGDITVLQNMTGLKEVWLHSNKFSGPLPDFSGLKELESLSLRDNSFTGPVPASLLSLESLKVVNLTNNHLQGPVPVFKSSVSVDLDKDSNSFCLSSPGECDPRVKSLLLIASSFDYPPRLAESWKGNDPCTNWIGIACSNGNITVISLEKMELTGTISPEFGAIKSLQRIILGINNLTGMIPQELTTLPNLKTLDVSSNKLFGKVPGFRSNVVVNTNGNPDIGKDKSSLSSPGSSSPSGGSGSGINGDKDRRGMKSSTFIGIIVGSVLGGLLSIFLIGLLVFCWYKKRQKRFSGSESSNAVVVHPRHSGSDNESVKITVAGSSVSVGGISDTYTLPGTSEVGDNIQMVEAGNMLISIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSLVELWKPSDQNPEDIYGIDLDMSLPQALKKWQAYEGRSDLESSTSSLLPSLDNTQMSIPTRPYGFAESFTSVDGR
What is the function of this protein?
Transmembrane kinase receptor (PubMed:1332795).  Phosphorylates only serine and threonine residues (PubMed:8224199).  Involved in auxin signal transduction and cell expansion and proliferation regulation (PubMed:23613767).  Forms with ABP1 a cell surface auxin perception complex that activates ROP signaling pathways (PubMed:24578577).  Required for auxin promotion of pavement cell interdigitation (PubMed:24578577).  Auxin promotes the formation of the ABP1-TMK1 protein complex (PubMed:24578577).
What are the official names of this protein?
Receptor protein kinase TMK1, BARK1-like kinase 1, Transmembrane kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYP_BREBN
Sequence: MKQSQMLIPTLREVPSDAEIASHKLLLRAGMARQLASGIYTYLPLALRSLHKIQAIVREEMNNAGGQELLMPAMQPAELWHQTGRWDVYGPELVRLRDRHDRPFALGPTHEEVITSLVRDEINSYKKLPINLYQIQTKFRDEVRPRFGLIRCREFIMKDAYSFDTSQDGLDRNFQAMYDAYTNIFTRVGLNFRAVEADAGAIGGKGTYEFMALCDIGEDTIAYSEEGDFAANLEKAEVVYKPSAKPATEAPAREKLHTPGIKTIDQLVQALQIEAKQIIKSLIYRVDDKLVMVLVRGDHEINEVKLKNLYDATIVGLASEADIVSVTGAPAGFVGPVGIDPEKVDIIADNFVQDVYDGVVGANETDYHLTHVVAGRDFTVSKYADLRNITEGDECPRTGGVIKFARGVEVGHVFKLGTKYSTAMGATYLDENGRSQPMIMGCYGIGVSRTIAAVIEQNNDENGIIWPVSVAPFHVHVIPVNVKVEEQRQASEQITEALRKAGIEVLFDDRPERAGVKFKDADLIGLPLRITVSDKAAQEGTVEVRIRKNGETHDVKLDQLVDEVKGILSRVDQTGAALFGN
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y707_BUCCC
Sequence: MTNKLKKMLKFPCTFTYKVIGLAQPELTNNIIKIIQNHIPGDYAPQIKSSNKGTYLSISITICAKNFKQIKNLYNELSKIHLVRMVL
What are the official names of this protein?
UPF0250 protein BCc_307.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: GUAA_ACET2
Sequence: MNNELILVLDFGGQYNQLIARRVREANVYCEVLPYNSSIDKIKSKNPKGIIFTGGPASVLDPKAPICDREVFELGIPILGICYGMQLMSHMLGGTVEKAEQREYGKVNITFDTSSMLFEGIEKESTCWMSHTYYVNNLPEGFVKCADTPNCPVAAIENREKKLYGVQFHPEVVHTPKGRDILNNFLYKICGCSGDWKMASFIEHSINSIREKVGDKKVLCALSGGVDSSVAAVLVHKAVGKQLTCIFVDHGLLRKYEGDQVEEVFKKQFDISLIRVNAEDRFLEKLKGVTDPERKRKIIGEEFIRVFEEEAKKIGTVDFLVQGTIYPDVIESGVGDAAVIKSHHNVGGLPDYIDFKEIIEPLRSLFKDEVRKVGIELGIPEDIVMRQPFPGPGLAVRVIGEVTKEKVDILRDADYIFREEIKNAGLDREINQYFAVLTGMRSVGVMGDERTYDYTLALRAVTTIDFMTADWAKIPYDVLEKVSNRIVNEVKHINRIVYDITTKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PYRH_ANADE
Sequence: MASEKASNPKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIGGGNIFRGVSGATEGMDRSSADYMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEPYIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEIHADVLLKATKVDGVYTDDPKKNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIGTTVGRPSARNA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2325_MYCTU
Sequence: MTTTSAPARNGTRRPSRPIVLLIPVPGSSVIHDLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAHIPRGALPSVPRWLWIVLAIGFLTAALAGGTPVVAVGGVQLGLGGALHFLRITALSVVLLALGAMVSWTTNVAEISPAVATLGRPFRVLRIPVDEWAVALALALRAFPMLIDEFQVLYAARRLRPKRMPPSRKARRQRHARELIDLLAAAITVTLRRADEMGDAITARGGTGQLSAHPGRPKLADWVTLAITAMASGTAVAIESLILHS
What are the official names of this protein?
Uncharacterized protein Rv2325c.
What is the protein family that this protein belongs to?
Belongs to the CbiQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNK_SCHPO
Sequence: MKPLVSPGLAKACTGLSLIGIVFLLVLSYLFSIEAETLMHDLVGSGLTGKQVAKTCLGAVVIYAVFFLFCGSQVIVSRYQKPVRI
What is the function of this protein?
Accessory component of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit f, V-ATPase subunit f.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PLSY_BRUO2
Sequence: MAEPGFFNAMLIGALIFGYVLGSIPFGLILTRLAGLGDVRAIGSGNIGATNVLRTGNKKLAAATLILDALKGTAAALIAAHFGQNAAIAAGFGAFIGHLFPVWIGFKGGKGVATYLGVLIGLAWAGALVFAAAWIVTALLTRYSSLSALVASLVVPIALYSRGNQALAALFAIMTVIVFIKHRANISRLLNGTESKIGAKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPAB1_MOUSE
Sequence: MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1, DNA-directed RNA polymerase II subunit E, RPB5 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHEU_ECO27
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: COBT_ECOLU
Sequence: MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLVNKIDVVRRAIMLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: FOLM_ARATH
Sequence: MAPLLSQTLIHTGRFLLRRFLEPPPAVISAVAASRVCFHRYYSSKSLSLVSPLGLHCSSLFSPPALCNSAFSSSATSTTIEVQSTEHEVVIALGSNIGNRMNNFREALRLMKRGGICVTRHSCLYETAPVHVTDQPRFLNAAVRGVTKLGPHELLSVLKTIERDMGRKDGIRYGPRPLDLDILFYGKMRISSDKLIIPHERLWERSFVLAPLVDLLGSAVDNDTVAHWHSLAIHPGGIFQAWERLGGESLIGQDGIQRVLPIGDKLWDFSNKTHVMGILNLTPDSFSDGGKFQSIDSAVSRVRSMISEGADIIDIGAQSTRPMASRISSQEELDRLLPVLEAVRGMPEMEEKLISVDTFNSEVASEAISNGADILNDVSAGTLDPNMHKVVAESGVPYMAMHMRGDPCTMQNKENLQYDDVCKDVASELYLRVRDAELSGIPAWRVMIDPGIGFSKSVDHNLDIIMDLPKIREEMAKRSIAVSHAPILVGPSRKRFLGDICGRPEATDRDAATVASVTAGILGGANIIRVHNVRHNADAAKVCDAMLRRRRSKG
What is the function of this protein?
Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis.
What are the official names of this protein?
Folate synthesis bifunctional protein, mitochondrial.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DHPS family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HUTG_STAAM
Sequence: MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPSGVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEELIDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDTRAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSHVSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIPSDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GLYA_TRIV2
Sequence: MTRTNSDFLTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGGCEFIDKIEQIAIDRAKQLFGAAHANVQPHSGAQANFAVFLTLLAPGDKIMGMDLSHGGHLTHGSPVNVSGKWFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAYPRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPYCHVVTTTTHKTLRGPRGGLILTGDAELGKKLDKSVFPGSQGGPLEHVIAGKAVAFGEALKPEFQGYSAQVIENARALANQLQNRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEVNITANKNTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEIGNIIADRLLNPDSDTVAQDCKRRVAALCDRFPLYPHLEIPVPVLA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE57L_XENLA
Sequence: MESVSKESYLPSFHQFPLCASLSEFESASSKETQSSALKNISPHPYDILQAPNSRALISALKTLQNKICRLESEKTHARDRLTNLSRAAGEHKKVLESEKRSAEWAAQEATSQKNDVAMQLNNAEQRCSLLEKQLDYMRKMMENADIQNNPIHQIPAQKEQKDMLEMQSKLQKLEVLENECLRLKATHKSSENKIQFLEEKLSVEEQERKALQDKAAQVQTSLEVNRILLSSASSQNSTQRKVKKKKQSKQKNAISKEPSSKEPLSKEPPSKCFFPKAGELPFVAGKSTTSSHSLSANVQNMLHMMKHQSPRVSQKDPKTVEHKPSILPGGSRSIPTRLMSSSTGDTLSDILLALQDELGQMSFEHQELLKHIDETKNTDMREDLERELDYLVKQMEIKSDQIIKLKRHQLNVAKLKKTAKKQPRPPSTTKPAEDEQNIGATDPCTPRNKGNLANGTGTPNSKASLELLKSVRKIQMTLKKDDIMWEK
What is the function of this protein?
Required for spindle microtubule attachment to both kinetochores and centrosomes.  Also functions to tether minus-ends of spindle microtubules to centrosomes.  May act by forming ring-like structures around microtubules, or by serving as a cross-linker or scaffold at the attachment site.
What are the official names of this protein?
Centrosomal protein cep57l1, Centrosomal protein 57kDa-like protein 1, Centrosomal protein of 57 kDa, Cep57, XCep57, Cep57-related protein, Cep57R.
What is the protein family that this protein belongs to?
Belongs to the translokin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to spindle microtubules.
Protein: YHAM_OCEIH
Sequence: MKNGIAFRTIGEEFDGFLLIKESTRGTTSNGKPFLTLILRDASGEIEAKLWDATKDDEETLIPEQIIQVTGEINQFRGKHQLKILSIRLSQPMDNVQVTDFLGKAPMEKEELAEKLTEAIFEMENPKIQRLVRAFIKKYQEELLTYPAATKNHHEFASGLAYHVVSMLAIGKELHKLYPEINRDLLYAGIILHDIGKIKELSGVVSTTYTLEGKMLGHIPMMVEEIGLMANELQIEGEEVLILKHLVLSHHGKAEWGSPTPPLVREAELLHLIDLIDAKMNMLGRALEKIQPGEFTERLFAMDNRAFYKPNFEENEG
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: ENL09_ARATH
Sequence: MARNLKSMMLCGFGLLCFLMIVDRAYAREFTVGGATGWTVPSGSQVYSQWAEQSRFQIGDSLLFVYQSNQDSVLQVTRDAYDSCNTDSPTAKFADGKTSVTLNHSGPYYFISGNKDNCKKNEKLVVIVMADRSGNKNTASSPPSPAPAPSGESAPSPPVSGTFEMTPAPTPTTSEDTPNSAASSLSFVAALLGAALASTLFLH
What is the function of this protein?
May act as a carbohydrate transporter (PubMed:24470637).  Mainly required for reproductive functions (PubMed:17293437, PubMed:19897921).
What are the official names of this protein?
Early nodulin-like protein 9, AtENODL9, Phytocyanin-like protein ENODL9, Sieve elements-specific ENOD protein.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: MURD_IDILO
Sequence: MTKIAWQNTKHIVVLGLGKTGVSVLRYLQHKRQQDQKLAEVKIQVFDSRENPPGLEEAKQILGDAELINRHWELEDTLAADLIIASPGIDLREDPVVLARDADIPIVGDVELFAQESKLPIVAVTGSNGKSTVTRMVEFVAKQCGKNVAAAGNIGVPVLDLLLQEQHPDAVILELSSFQLESVSSLKLKAAALMNISADHMDRYCTLDEYVKAKQRIFTHAKTWILNRQQQDTWPHPVTGKLMTFGNDSHPKHFGLLSGNIDRVSGPVAVTFDGSVVLRADQLQLQGIHNLVNVQAALALCQAIDIDIEAAVRAVKEFKGLPHRCELVSDNEGVLWVNDSKATNIGATAAAVEGLRPMINGRLLLIAGGVGKGADFRELQSTLERVDILLTIGEDGPRIGQLFNGSRQVKSLQQAVELAASLVQTGDMVLLSPACASFDQFQNFEHRGDSFRHAVEALYVNSA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_SINMW
Sequence: MSTVEAAKPKTEVSPLLKLVLELGPLMVFFFANSRGEWLASRFPVLADLGGPIFIATGLFMAATAAALAVSWMMTRTLPMMPLISGIVVFVFGALTLWLQNDTFIKMKPTIVNTLFGAILLGGLLFGKSLLGYVFHAAFKLDEEGWRKLTVRWGVFFLFLAVLNEVIWRSFSTDFWVAFKVWGTMPITILFTLAQMPLIMKHSVDQENAK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_SCHPO
Sequence: MRRAFVERNTNETKISVAIALDKAPLPEESNFIDELITSKHANQKGEQVIQVDTGIGFLDHMYHALAKHAGWSLRLYSRGDLIIDDHHTAEDTAIALGIAFKQAMGNFAGVKRFGHAYCPLDEALSRSVVDLSGRPYAVIDLGLKREKVGELSCEMIPHLLYSFSVAAGITLHVTCLYGSNDHHRAESAFKSLAVAMRAATSLTGSSEVPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: YQGF_BURA4
Sequence: MSGASARDATLLGFDYGEKRIGVAIGNALTRSARALVVIPNLNREHRFKAVGDLLAEWRPDALVVGLPMHPDGTPHEMTQQAKRFGNQLNGRFGLPVTWVDERYSSVEAEAGLRERNVRGRARAEMLDAEAARVILQQYLDQLSDHEHH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.