PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_TROW8
Sequence: MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRREKVVTGVHKACQGRPVTKADLAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVAYIRFASVYQDFDSLEDFSRAVERLKNQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MECOM_HUMAN
Sequence: MRSKGRARKLATNNECVYGNYPEIPLEEMPDADGVASTPSLNIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDPSYGWEILDEFYNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERPFEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKLTEPRKNHVFGGKKGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLDEEDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSTSHSSSNVWHSMARAAAESSAIQSISHV
What is the function of this protein?
Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro.  Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation.  Likely to be one of the primary histone methyltransferases along with PRDM16 that direct cytoplasmic H3K9me1 methylation.
What are the official names of this protein?
Histone-lysine N-methyltransferase MECOM, Ecotropic virus integration site 1 protein homolog, EVI-1, MDS1 and EVI1 complex locus protein, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.
Protein: DHKI_DICDI
Sequence: MIYLKILEKLNQAIWLFDINKRVLIWGNQSCKKYKNIESITSLFNNSNLINDIRNGKSKHEHIDIIESNENGEILKQMIFKYSSIHISDMDARQLYLDTSINLLVNQDSHYLDYEGKRIFILVEAIEEIKFIQSPLSSSIENHNINNNQNNQNSVNINSSNKGQYNRPEPSNMGSWEWNVQNDTTKASNQFYKIIGIENDFNKKLNFNDFINKLGIQEIQPIINNCIESNSSSFEYPLRINRKNDNLVRYIQLKGEIIKKDDKVFKVLGVCHDFSEIQEAKDKLEEESKFVEALIGCLKAGIVACNSNGDLTHFNKSAQDLHGLELNDKTDRKQLLDQILKCYRSPYEQINLEKSGTPIIRALSGEFINDQEIIITPTSNQQQSSLSKSNRPRSQSNCSNGNKSQNRLSKNYSTTTTTTNNNNNNNNNNNNNNNNNNNNNSISQQQQTQVSTQQTQQQQNTTNGIGGATTSTTAAAATITSPQQIPIATKIPTKINDNEFLVLASGQEIVSKDGKTIGAFVALHDITERKRNEVILKNATEEAQRANQLKGEFLANISHELLSPMNSIIGMVGLCLDVAPRNLKEMLNDVVESSKILLDLLHQILDFTTLESNSLAVRPFPFKLRDTFNQLFKVFYTRIIEKKISLTFSIDPNIADDFYGDQNRLKQILSNLIDNAIKFSNSSNINNSISIIVEQLTHNQFKKYKDSFRSNSKTHSRLNSHDDYSIDGDYDDQDNNDSYFGRDINVSDNESAVGGFSELDEKDNSDDDDENDDENDETDENDDDTDDDTSSNTSRNNISNNLLFHNNTSGGGGGGINKREKFKKKDREGFVNLKFSIKDRGIGVPEDKHDFIFDRFFQVDGSYSRVQGGVGLGLSICKKLIEFFGGAIWFESEASQGSTFHFILSIKSVEAPSPKSPSLQSSNGSINSTTKLFESSRLKNEIYIPSLPNVQTKKVKKDSNDNGNNDSTNYGISLSNSMNNININGSTLNNNNSINNNNNSNDNGPLTSRTPSNSYYNFIASLNNTSLKSSSHNTLSSSPTGFNGISNLNISGLNNLSNLSNNPNNLNNIIGNTNGNNNTNGNNNSGISLNNSNNNIQTPNGLNNSRGSSLISTPSTKNVKKQHSCPMDLIQRIHSICTPRGPISKECGLNNLPAYSPPKSPGRSLSHGGKNYSNLISTPRGGVGYSSPPINSSSSSGGGSSTNGSNSGNSSANNSTPSSSSLSSTPLTSSNTPSPVSISSNNVNNNNQQQQTQPILSPILPLKDNSIDISDLNNINSLTPNSSNSTSTNVTQSSSNIINNGNSITIINNNPVTPNGKKIVIVPLLSLQSASSPKQSQRGYSPKQQYSPKQYSPKQQYSPKQYSPKQQQQQQQQQQQLEQLSGRMSPHKSNLSSTNLHHIHHHHIHQQQSQQHNNTTVHSNNLILNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTNTSNNHTSDPSKSSNSTPETSPPISSPRSNNNNNCSLTTIVGVTTPPQPSSTITTPQFQSPPILSGNSGNINLLSSNGTSSGGIEISGSQMIPQKVLVAEDNTMNQKLIKTLLTKRGFDITIAKDGKQALDFYHESKNKSILYDCILMDIQMPILSGLEATCAIREIEANEGGHIPIIAVTAHAMKGDKEKFLESGVDDYVTKPINPKLLYEVINTQICKYIEENRSSSTINENKNTINNNNNNTNNNNNNNNSSNPVNNNNSNSIDATQQELNNEKIRI
What is the function of this protein?
Acts as a receptor histidine kinase for a signal transduction pathway.  This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
What are the official names of this protein?
Hybrid signal transduction histidine kinase I.
Protein: BGALA_PENSQ
Sequence: MKLLSSWVVAALAAQAAGAAISHKLDGFTIREHADPAKRALLQKYVTWDEHSIFVNGERLMIFSGEVHPYRLPVASLYIDIFEKVKALGFNCVSFYVDWALLEGNPGHYSAEGIFDLQPFFDAAKEAGIYLLARPGPYINAEVSGGGFPGWLQRVDGILRTSDEAYLKATDNYASNIAATIAKAQITNGGPIILYQPENEYSGACCGYNGFPDGSYMQYIEDHARDAGIVVPFISNDAWAAGHNAPGTGAGAVDIYGHDSYPLGFDCANPSTWPSGNLPTYFHTSHEQQSPSTPYSLVEFQGGAFDPWGGVGFAKCAALLNHEFERVFYKNDFSFGVAFLNLYMIFGGTNWGNLGHPGGYTSYDYGSAISESRNITREKYSELKLLGNFAKVSPGYLVANPGDLSTSTYTNTADLTVTPLLGSNSSASSFFVIRHSDYSSQASVEYKLTVPTSAGNLTIPQLGGSLTLSGRDSKIHVTDYDVAGTNILYSTAEVFTWKKFNNEKVLVLYGGPGEHHEFAVSGASSSSVVEGSSSGISSKKVGKALVVAWDVSTARRIVQVGSLKVFLLDRNSAYNYWVPQVPTKGTAPGYSNQETTASSIIVKAGYLVRSAYLDGNDLHIQADFNATTPIEVVGAPSGAKNLVINGKKTQTKVDKNGIWSASVAYTAPKVQLPSLKSLKWKSVDTLPEAKNTYDDSAWTSADHAYTNNSAHSLQTPTSLFASDYGYHTGALLFRGHFTANGKEKTFFVQTKGGTAYGHSIWINETYVGSWAGTSINDNNNATYTLPTLQSGKNYVITVVIDNMGLDEDWTIGSEDMKNPRGIIQYSLSGQEASAISWKLTGNLGGENYRDTVRGPLNEGGLYAERQGFHQPQPPTQKWDSSSPFTGLTKPGIRFYSTSFDLDLPSGYDIPLYFNFGNSTSTPAAYRVQLYVNGYQYGKYVNNIGPQTSFPVPEGILNYHGTNWLALSLWAQEDNGAKLDSFELINTTPVLTSLGEVKSVNQPKYQARKGAY
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.  Has high in vitro transglycosylation activity with p-nitrophenyl-beta-D-galactopyranoside, methyl-beta-D-galactopyranoside or lactose as a donor and galactose as an acceptor.
What are the official names of this protein?
Beta-galactosidase A, Lactase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL292_ARATH
Sequence: MAKSKNHTAHNQSAKAHKNGIKKPRRHRHTPTRGMDPKFLRNQRYARKHNVKSGENAGVEE
What are the official names of this protein?
60S ribosomal protein L29-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL29 family.
Protein: RS7_ERYLH
Sequence: MSRRRRPEKREILPDPKFGDQVLSKFMNNLMLDGKKAVAEGIVYTALDTVEAKAKTDPVQLFHDALNNIKPQVEVRSRRVGGATYQVPVEVRPERAQALAIRWMISAARGRPETTMAARLSGELMDAANNRGNAVKKREDAHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RPIA_BURM7
Sequence: MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: TXAG7_AGEOR
Sequence: MTQAFFFLLLVSLVASTLSKEFNFCPRAIDEVCPVKEKRNECCSSKECRFGEMCCSEPCGNVCRVKSDTPLGFPAKEDSNCKVGEIKKKWYQKVWSKITKWG
What are the official names of this protein?
U7-agatoxin-Ao1a, U7-AGTX-Ao1a, AgorTX_A5.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 02 (wap-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RHAM_ECO81
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKAHNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANADNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBB1_RAT
Sequence: MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Transducin beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: SIA8B_HUMAN
Sequence: MQLQFRSWMLAALTLLVVFLIFADISEIEEEIGNSGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDSTMNVSQNLYELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHHVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
What is the function of this protein?
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
What are the official names of this protein?
Alpha-2,8-sialyltransferase 8B, Sialyltransferase 8B, SIAT8-B, Sialyltransferase St8Sia II, ST8SiaII, Sialyltransferase X, STX.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: HFQ_ALKEH
Sequence: MAKGQSLQEPFLNALRKEKVPVSIYLVNGIKLQGQIESFDQFVILLRNNVNQMVYKHAISTVVPARNVRTAPPVPTETHAQSSEEFGNI
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PIMT_PELTS
Sequence: MLLKRAAGKEKDDDNRAGERRRMVYEQLISRGIENDDVIQSMLEVPRHRFVPKHLQEYAYQDGPLAIGEGQTISQPYIVALMIEALEPAPSDRVLEVGTGSGYAAAVLSRIVSVVYTIERFDSLARGARSLFQSLKYDNIYVRTGDGTKGWPEAAPFDGIIVSAGAPAVPQTLCGQLKPGGRLVAPVGDKRWQELLVVRRALDGGYNVKKLGTVFFVPLVGEEGWHDET
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_PSYIN
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSRAGEQLDEISEGYLSTLLRRGDIEGKIGQVLFLHNVPNVLSERVLLVGCGKERELTETQYKQIIAKTITTLNDTGALEAICFLSELHIKGRDTYWAVRQATEATQDCLYNFDKFKTNKENTRRPLRKLTFNVTSRKELARAELGLQHALAVASGAKACKDLANMPPNICTPLYLSEQAIALGQRFEKITTEIVDSEQMAELKMDSYLAVAKGSANPAYMSLMHYNGGNADQKPIVLVGKGLTFDSGGISLKPGEAMDEMKYDMGGAASVFGAMKALAKLNLPINVIGILAGAENMPAGNAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPDCVVDIATLTGACIMALGHHISGLMTPHKGLANELLSASNQSSDKAWQLPMDDEFQKQLESPFADMANIGGRPAGSITAACFLSRFTKSYTWAHLDVAGTAWRSGANKGSTGRPVSLLTQFLINRSENETTAVNS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PSE14
Sequence: MAEITAALVKELRERTGEGMMDCKKALTKAGGDIEKAIDDMRASGAIKAAKKAGNVAAEGAIAIKDDGKAAVIIEVNSQTDFLALQDDFKAFVAASVEKAFADKLTDVAPLIEAQEAARLVLVGKVGENVNIRRLKRIEGDVVGTYLHGNKIGVVVTLKGGNVELAKDIAMHVAASNPEFLFPSEVSAEAIEREKNVFLQLNEDKIKGKPAEIVEKMVGGRITKFLAEASLVEQAFVKNPEVKVGDLAKKAGAEIVSFTYFKVGDGIEKPVDNFADEVAAQLAAAKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP39_BRUSU
Sequence: MHKLLKLAAMGTAACALLAGMAPVANAQEKQNVEVLHWWTSGGEASALEVLKKDLESKGISWTDMPVAGGGGTEAMTVLRARVTAGNAPTAVQMLGFDIRDWAKQGALGNLDTVASKEGWEKVIPAPLQEFAKYDGHWIAAPVNIHSTNWMWINKAALDKAGGKEPTNWDELIALLDNFKAQGITPIAHGGQPWQDATIFDAVVLSFGPDFYKKAFIDLDPEALGSDTMKQAFDRMSKLRTYVDDNFSGRDWNLASAMVIEGKAGVQFMGDWAKGEFLKAGKKPGEDFVCMRYPGTQGAVTFNSDMFAMFKVSEDKVPAQLEMASAIESPAFQSAFNVVKGSAPARTDVPDTAFDACGKKAIADVKEANSKGTLLGSMAHGYANPAAVKNAIYDVVTRQFNGQLSSEDAVKELVAAVEAAK
What is the function of this protein?
Part of a binding-protein-dependent transport system for a sugar.
What are the official names of this protein?
Probable sugar-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUCS_STRCO
Sequence: MRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCALKEGTGEEEGVWTVVNKAGEKLIITMEEILHDSSHELGVDPGLIKDGVEAHLQELLADRIDTLGEGYTLIRREYMTAIGPVDILCRDAQGGTVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVRGVFAAQEIKPQARVLATDRGIGCQVLDYDALRGIEDDKLRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG8_DROER
Sequence: MMKDYYTWTYPDIPEDVAQKLQQLKNSLVVVGIVGRSKCDQANKMQAFGMEPPIEHTAKDGQVQCYYKPGTSSLLLHFETTYDEAILGQMIDVCMEDVDTPFDFDSFYERMRCRFVRMMLLALHACHIVVYVETGPTFDPTLVTVFQLLKFAREQHLMQFLPQMLRETPAARMSEKTRLCAPRILFLFENFPRDEPKTRECVSAYEFQTEDCIYELLRHHTIVTNSSSTSLVALPNNKQFVFFNAHEQLHEDKLLKAIECLNQAMYKPDAKEEEEDLEILELAPFDGFVKPYNLPVDEKELEKQQYKKDHTVWHFLQRHVQDALLGCFDEGSFKQHSQHGQFQLLNIQEWHDYMATLHKLLVENAKDPNHETSNEEYKLFLKCFDESLNYEKKFWTHLCELGLKKGIAAYKNAAPANYGSATHRQLLADATVAFEEEGRGPQAKAALAKLAAICQKYWQDGRQQCEQLSLRSHPCTLPKNLPHEKHNSAVIHISSCNCGRTQGRREDPFSMRQANYEFYEHIAQMCNLCVKVKHYKFPVFEPSVSDYRAAAFEAAFPLLHTAKSGARQGEEGDDEPEDEVVQEQQQPVEEQRQNTASNGCSQPLSPTFGSDLNMSIAGFGASLNESQASSEQLSNSEQNTSSSGTSSADTENELVVELQEPAKKETREDAGPADALPTSTTEYLPGLVHTVSNFGLLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVQLRLVHAPKQQHHTHHQQQHPGKKQQRWKKQGDRLSLKIFVGMEYECSRGHRFMMCAPDRVLRGGADIERDTCSKVVHNNMPLYYPCPCRSQTSYLAQLMRIHVVTPKAPVNIIVDPKVCVGKEKYTFTLGSIVPPRLSQSAYWIIRLPYIYQGDDVIIAPPEKLEPDDPLAGGYLLPGMFGVAETDATQDLNEPGRMGASAAEDFTRI
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: NEF_SIVTN
Sequence: MGNIFGRWPGARKAIEDLHNTSSEPVGQASQDLQNKGGLTTNTLGTSADVLEYSADHTEEEVGFPVRPAVPMRPMTEKLAIDLSWFLKEKGGLDGLFFSPKRAAILDTWMYNTQGVFPDWQNYTPGPGIRYPLCRGWLFKLVPVDPPEDDEKNILLHPACSHGTTDPDGETLIWRFDSSLARRHIARERYPEYFK
What is the function of this protein?
Plays a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis.  Protects the infected cells from apoptosis in order to keep them alive until the next virus generation is ready to strike (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Host cytoplasm, host perinuclear region. Virion. Secreted. Note=Predominantly found in the paranuclear area, probably in the TGN. Correct localization requires PACS1. Also associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Also incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved (By similarity).
Protein: CA1AB_XENLA
Sequence: MPGKEAAGDVMKSSTKSNTKKMVQARLPFKRLNPVPKDEGCLEEKKIRIPQNVSPQKMLYSLNSSMEDMENDCEMETEMTPIPKAINGKGPLDNYIRKAPKASNAPSIITIDLTEDSNISTSNDSPLNGESRAQLANGTVSPERSTTNAPLSTNEECTVSVDNKSLENMSFPELELDKPHQSAASCTSVSNFSPERAVKEDYNSSADDDSVSVSSSSSPVSLSSPDVQTGSKFTNGSSPSTSTTPTGKATSNKTSAEKKKTKDKAEKRQAEKEERECARREARAAKDLAKKKREGEREQREKDKKEKKEREDREKAEKNRLKEEKKKEKLEALEAKQEEKRKKEEEKRQKEEEKRLKEEEKRIKAEKAEITRFLQKPKTPQAPKTFARSCGKFAPFEIKKGMALAPLCRIDFEQEASEELDIFLQEQTSESSFLDEIKKRRPRKMGQTTVPTINSVEVDDVQVLGETDPVLGSNMVLEEHIKDIGVPERKKFGRMKLLQFCENHRPAYWGTSNKRSRVINPRKPWAQDTDMLDYEVDSDEEWEEEEPGESLSHSEGENEDDDPKEEEDEDDDGFFVPHGYLSNDEGVSDEECTDPENQKVRQKLKAKEWDDLQSNSKKIRVLQPVVIGCVWCDSKASEIRLLQKFSACILESPAVEEELTQDISSAQKIKDRQILSKLVPLLHGNVNGSKIIIQEFQECCRRGLFLEDNASHATDIESTSPNSTPQTPSNIIVPSKARLKRLISENSVYEKRPEHRMCWYVHSDVLKGLQQDNLPVPCQWTYITQVNSVSKENNGANGGSLQSLPLSGKRKSAGSMPITKFMKRARDLETAVNTDMDGFQADTEEEEDDDDCMIIEDQQAKDAEDSTIECKINLNDSAILASCQN
What is the function of this protein?
Involved in chromatin assembly in DNA replication and DNA repair.
What are the official names of this protein?
Chromatin assembly factor 1 subunit A-B, CAF-1 subunit A, Chromatin assembly factor I p150 subunit B, CAF-I 150 kDa subunit B, CAF-I p150-B, xp150.
What is the protein family that this protein belongs to?
Belongs to the CHAF1A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1022_METTH
Sequence: MFLDPVINFFGTVLEMFRSGGVITYLIAAIGIYGFITALEKIHYLRKISRVSTPQIIGAVNESMEKGGALEALREIGQYQNPVSKIISEALKIGYRNRSEVEDAMERVFIVEMSNMTRGLGTLRTIIEVAPMLGLIGTVIGIWYTFRALGVNADPAAMAEGIYVALITTILGLAVAIILMPLYSYITGRIDDEIDKIELIKKMTNWGYAVMRISVEGNVDDVVKALMESDGVVSVRVVDEPDANVVVAFKPSMLEKSINNIIIERCGKSAEIIESKLRQ
What are the official names of this protein?
Putative biopolymer transport protein ExbB homolog.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_STRPD
Sequence: MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTRAGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TUSA_ALIFM
Sequence: MTINFDTATQTLEAEGLRCPEPVMMVRKTIRKMEDGETLLIKADDPSTTRDIPSFCRFMDHELIAEDTDSLPYRYLIRKGLSK
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSP3_CAEEL
Sequence: MAQSVPPGDIQTQPGTKIVFNAPYDDKHTYHIKVINSSARRIGYGIKTTNMKRLGVDPPCGVLDPKEAVLLAVSCDAFAFGQEDTNNDRITVEWTNTPDGAARQFRREWFQGDGMVRRKNLPIEYNP
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein 3, MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: ATPB_SHISS
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.