PharMolix/UniProtQA huggingface dataset:
Protein: LEUC_THEFY
Sequence: MARTMAEKVWEEHVVRRAEGEPDLLYIDLHLIHEVTSPQAFEGLRLANRKLRRPDLTIATEDHNVPTENIFLPIADPVSRTQVETLRKNAAEFGVRLHPMGDIDQGIVHVIGPQLGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSQVEHVMATQTLPMTPFKTMAVNVEGKLKPGVTAKDIILAVIAQIGTGGGQGHVIEYRGEAIRSLSMEARMTICNMSIEAGARAGMIAPDQTTFDYLKGRPHAPKGELWDQAVEYWKTLPTDEGAVFDKEVFLNADELSPFVTWGTNPGQGVPLDSVVPDPESFTDPVERAAAEKALAYMDLKPGTRMRDIKIDTVFLGSCTNGRIEDLRAAAEVLKGRKVADGVRMLVVPGSQRVKQQAAAEGLDEIFKAAGAEWREAGCSMCLGMNPDTLKPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPADL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MSCL_BRUAB
Sequence: MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGDPKTTLAAAREAGATIAYGNFITLLINFLIIAWVLFLVVKLMNRLKKREEAKPAPAAPSEEVLLTEIRDILAKQQKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCGL_ECOSM
Sequence: MPKPGILKSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMILPLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK
What are the official names of this protein?
Protein YcgL.
Protein: EIF3E_SCHPO
Sequence: MGSELKSTSPLAVKYDLSQKIMQHLDRHLIFPLLEFLSLRQTHDPKELLQAKYDLLKDTNMTDYVANLWTNLHGGHTDEDMANAFAEKRRSVLQELSELEEEVQGILGVLENPDLIAALRQDKGQNLQHLQEHYNITPERIAVLYKFAQFQYNCGNYGGASDLLYHFRAFSKDPELNASATWGKFASEILTVDWDGAMEELGKLREMVDSKSFKDSAVQLRNRTWLLHWSLFPLFNHANGCDTLCDLFFYTPYLNTIQTSCPWLLRYLTVAVVTNQNNANQKPRNPRQSYQRRMRDLVRIISQENYEYSDPVTSFISALYTEVDFEKAQHCLRECEEVLKTDFFLVSLCDHFLEGARKLLAEAYCRIHSVISVDVLANKLEMDSAQLIQLVENRNNPSVAAASNVAADQSTEDESIESTSTNVVADDLITEAETATEAEEPEPEVQFGFKAKLDGESIIIEHPTYSAFQQIIDRTKSLSFESQNLEQSLAKSISELKHATV
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential).  Required for maintaining the basal level of atf1 and for transcriptional activation of core environmental stress response genes (CESR genes) in response to histidine starvation (PubMed:18502752).  May positively regulate proteasome activity (PubMed:12553909).  Required for nuclear localization of the proteasome subunit rpn501/rpn502 (PubMed:12553909).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_YERPS
Sequence: MAVQQNKPTRSKRGMRRSHDALTTATLSVDKTSGETHLRHHITADGFYRGRKVIG
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: FSL3_GIBZE
Sequence: MSVTRLSEPLQNILLQDLRNFYDRASRIATLSVSAIAAIKSAWTRGSPFAAATALYPTNEEGKYVIQAEGIRMEFTNYGGAVTNLWLNNSRGEEVDIVLGLDHARDYEDYPKNPYLNGAIGRYAGFMRGGRFDMDGESYQVATNAHNGSSTFNGGDRGWGRSILDIGSHTENSITFVLFDRSWNGFPGTAASCLTHTVTPYEWRVAFGVTPTKKPGPINMSQQAFFNLDGFKKKNLTGSVPVSDKTVRDHKLHLPLSGLRFETDALGLSTGDILGNPRGSEYDFWSASRRIGDVLEKPYMGICDRCQKRQYHNHNPSGAYDTIFQLGRSQPWNKEDVPAAILSSPESGISMKLYSDQEALHVHTWSQKEFPLKLKKGQGQGMVPQHGGISFEMQDWPDGLNHPEWRRESKTIWGMDGLYTAFSSYRFSVDKTEP
What is the function of this protein?
Epimerase; part of the gene cluster that mediates the biosynthesis of fusarielins F, G and H, decaketide compounds with 5 methylations and a decaline core that act as mycoestrogens as they stimulate growth of MCF-7 breast cancer cells (PubMed:22252016, PubMed:27983606).  The initial compound in the pathway is produced by the reducing polyketide synthase FSL1.  FSL1 lacks an active enoyl reductase (ER) domain and biosynthesis of fusarielins relies on the trans-acting enoyl reductase FSL5, before it is released through hydrolysis catalyzed by the thioesterase FSL2 (PubMed:22252016, PubMed:27983606).  Fusarielins F, G, and H have a C11=C12 cis double bond and is fully reduced between C10 and C11 and between C12 and C13.  FSL3 can be involved in the formation of the C11=C12 cis double bond by moving a hypothetical C10=C11 or C12=C13 trans double bond to form prefusarielin (PubMed:27983606).  Prefusarielin is oxygenated at C15 and C16 by the cytochrome P450 monooxygenase FSL4, resulting in fusarielin F, which subsequently is epoxidized into fusarielin G by the same enzyme (PubMed:27983606).  The final step in the pathway is a reduction of the carboxylic acid moiety to yield fusarielin H via a still undetermined mechanism (PubMed:27983606).
What are the official names of this protein?
Epimerase FSL3, Fusarielin biosynthesis cluster protein 3.
What is the protein family that this protein belongs to?
Belongs to the aldose epimerase family.
Protein: GKAP1_BOVIN
Sequence: MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTNKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAICNAQHELSLPNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYENAENASTQSKVMNKKDKRKTHQGKDKPLTISLKEFQSEDHISKKTEELSSQILSHDGGFFNRLEDDVHKILTREKRREQLTEYNGTDNYTVHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVIAQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR
What is the function of this protein?
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase.  Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane.  Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
What are the official names of this protein?
G kinase-anchoring protein 1.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: SPF27_DANRE
Sequence: MAGPASVAGDVFVDALPYFDQGYDATGVREAAAALVEEETRRYRPTKNYLSYLPTPDFSAFETEIMRNEFERLAARQPMELLSMKRYELPAPSSGQKNDMTAWQDCVNNSMAQLEHQAVRIENLELMAQYGTNAWKMSNDNLALMIENSQKELQNVRKEIQDLNWQRKNDQLAGGAKLRELESNWVSLVSKNYEIERAIVQLENEVAQMKQQQGDENKENIRQDF
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.
What are the official names of this protein?
Pre-mRNA-splicing factor SPF27, Protein BCAS2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPF27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_ROSS1
Sequence: MAEPRYRRILLKLSGEALAGKGTHSIDPNMLDYYAEEIERVHRHGVQVAVVLGGGNIWRGNQAIARGMDAAQSHYMGMLATIINALALQDALERRGIFTRAMTAIKMDEVAEPYIRRRATRHLEKGRVIILAAGTGNPYFTTDSAAALRAAEVHAEVILMAKNGVDGVYSADPRRYPDAKRFEYISYMEALSRGLTVMDSTALTFCMDNNIPIIVFDPLTPGNIERIVMGEHVGTLVSSHPSQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5487_ARATH
Sequence: MLFWVLLSSFCVFCFSSPDGFLSLSCGGSSYTAAYNISWVSDNDYIETGNTTTVTYAEGNSTSSVPIRLFPDPQGRQCYKLPVRKDLSSVLIRATFVYRNYDSQNSPPAFHVSLGRRITSTVDLRTNDPWIEELVWPVNNDSLLLCLLAVKGRGIPVISSLEVRPLPLGSYKYSLEGSPDIILRRSYRINSGYTNGTIRYPSDPFDRIWDPDQSYSPFHASWSFNGLTKLNSFNITENPPASVLKTARILARKESLSYTLSLHTPGDYYIILYFAGILSLSPSFSVTINDEVKQSDYTVTSSEAGTLYFTQKGISKLNITLRKIKFNPQVSALEVYEILQIPPEASSTTVSALKVIEQFTGQDLGWQDDPCTPLPWNHIECEGNRVTSLFLSKINLRSISPTFGDLLDLKTLDLHNTSLTGAIQNVGSLKDLQKLNLSFNQLESFGSELEDLVNLEVLDLQNNSLQGSVPETLGKLKKLRLLNLENNNLVGPLPQSLNITGLEVRITGNPCLSFSSISCNNVSSTIDTPQVTIPINKKQRKQNRIAILLGVSGGALFATFLVFVFMSIFTRRQRNKERDITRAQLKMQNWNASRIFSHKEIKSATRNFKEVIGRGSFGAVYRGKLPDGKQVAVKVRFDRTQLGADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRHSLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNAKVSDFGLSKQFTKADASHITTVVKGTAGYLDPEYYSTLQLTEKSDVYSFGVVLLELICGREPLSHSGSPDSFNLVLWARPNLQAGAFEIVDDILKETFDPASMKKAASIAIRCVGRDASGRPSIAEVLTKLKEAYSLQLSYLAASAHTD
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At5g48740.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TF2H5_CAEEL
Sequence: MVNVKKGVLVTSDPAFRQLLIHLDDSRQLGSKFIVRELDDTHLFIEKEIVPMLENKVEQIMENMNPEAVDK
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and in RNA transcription by RNA polymerase II (By similarity).  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment (By similarity).  In transcription, TFIIH has an essential role in transcription initiation (By similarity).  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape (By similarity).  Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell (PubMed:34824371).  Required for efficient binding of TFIIH to damaged DNA (PubMed:34824371).  Dispensable for normal development, but required when transcription is challenged (PubMed:34824371).
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB5, TFIIH subunit GTF-2H5.
What is the protein family that this protein belongs to?
Belongs to the TFB5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localized to paired homologous chromosomes (bivalents) about 10 minutes after UV irradiation, but localization is lost after 35 minutes, probably as a result of successful DNA damage repair as part of the TFIIH complex.
Protein: PYRB_YERPG
Sequence: MANPLYHKHIISINDLSRDELELVLRTAASLKKTPQPELLKHKVIASCFFEASTRTRLSFETSIHRLGASVVGFSDSSNTSLGKKGETLADTMSVISTYVDAIVMRHPQEGASRLAAQFSGNVPIVNAGDGANQHPTQTLLDLFTIQETQGRLDNINIAMVGDLKYGRTVHSLTQALAKFNGNHFFFIAPDALAMPAYILQMLEEKEIEYSLHESLEEVVPELDILYMTRVQKERLDPSEYANVKAQFILRSSDLTGARDNLKVLHPLPRIDEITTDVDKTPYAYYFQQAGNGIFARQALLALVLNAELAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CTSR_STAAW
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: GMFB_PONAB
Sequence: MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH
What is the function of this protein?
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
What are the official names of this protein?
Glia maturation factor beta, GMF-beta.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein: LIPB_SYNS9
Sequence: MDIGKLVTRRSSEHPAGAFLFEPSVLIPFERAWRDQQLWQQRLFEEPSSPEAVWILQHPACYTLGRGASAQHLHFDPNEPPAPLHRIDRGGEVTHHLPGQLVAYPVLDLQRHTPDLHLYLRQLELVVIDVLRDLGLQGECLPGLTGVWVGRCKVAAIGVGCRRWITQHGLALNVDCELQGFAEITPCGLVGHQVGRLCDWMPGLRVSDVQPLLRQSLAARFHLAWIPQA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO1_PSEAE
Sequence: MSQAPLVLVDGSSYLYRAFHALPPLTTSTGKPTGAVKGVLNMLLSLRKQYPDSPFAVVFDAKGPTFRDELFAEYKANRPSMPDDLRVQVEPLHASVRALGLPLLCVEGVEADDVIGTLARSSAAADRPVVISTGDKDMAQLVDGHITLVNTMTGSRLDVDGVKEKFGVGPELIIDFLALMGDKVDNIPGVPGVGEKTALGLLTGVGGGLEVLYASLDKVPELPIRGAKGLPAKLEENREQAFLSYQLATIKTDVELDVEIDKLYPGEPQREALIALYRELEFKNWLDDLLREAKEAGENGEAETPIQAEVDYDVVLDQAGFDAWLKKLEEAELIAFDTETTSIDAQQAQVVGVSFAVKEGEAAYVPLAHSYMGVPEQLDRDAVLRALKPLLEDPKKLKVGQHAKYDINVLANASTPIALRGVAYDTMLESYVLDSTATRHDMDSLALKYLGHSTIRFEDIAGKGAKQLTFDQIAIEQAGPYAAEDADVTLRLHQALWQKLEAIPSLARVLTDIEMPLVPVLARIERNGALVDANLLGIQSRELGEKMVALERQAYDLAGQEFNLGSPKQLGAILYDKLGLPVLSKTATGQPSTAEAVLAELAEQDFELPKVIMQYRSMSKLKSTYTDRLPEQINPRTGRIHTSYHQAVAATGRLSSSDPNLQNIPIRTAEGRRIRQAFVAPQGYKLLAADYSQIELRIMAHLAKDDGLLDAFRHDLDVHRATAAEVFGVPLEDVSGDQRRSAKAINFGLIYGMSAFGLAKQIGVERKEAQAYIDRYFARYPGVLAYMERTRAQAAEQGFVETLFGRRLYLPEIHSKNGAMRKAAERTAINAPMQGTAADIMKRAMVAVDNWLQESGLDARVILQVHDELVLEVREDLVEQVCEGIRPLMSGAATLDVPLVVEAGVGSNWDEAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: HIS1_CHRVO
Sequence: MKLTIALSKGRIFEETLPLLAAAGIVPAENPESSRKLIIGTNHPDVQLVIVRASDVPTYVQYGAADLGIAGRDVLIEHGGAGLYQPLDLNIAKCKMMVAVQEGFDYDAAVRRGARLKIATKYPQIAREHFAKKGVHVDIIKLYGSMELAPLVGLADAIVDLVSTGGTLRANKLAAVEHIIDISSRLVVNQAALKLKYDAIQPVLDAFAGAVPA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALC_RAT
Sequence: MGFLKFSPFLVVSILLLYQACGLQAVPLRSTLESSPGMATLSEEEARLLAALVQNYMQMKVRELEQEEEQEAEGSSLDSPRSKRCGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAPGKKRDMAKDLETNHHPYFGN
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBE_SAIBB
Sequence: MVHFTAEEKAAITSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: KUP_BORA1
Sequence: MSHTSEQGASRPVALMMGALGVVYGDIGTSPLYTLRACLTEFADLQPAHILGVLSILFWLLMVVVSFKYVLLILRADNQGEGGTLALLELAVRGRSGRLRTFFVVLGIFGAALFYGDSMITPAISVLSAIEGIGVVSHTLDPWIVPLALLVLLALFAIQSRGTGTVGKLFGPVMVVWFATLGVLGGWQVWQTPEVLVALNPIWALRFVFEFPVMSFLLLGAVVLALTGAEALYADMGHFGRPAIRRAWFSMVLPSLTLCYLGQGALLLRDPSAIRNPFFLMAPEWGLAALVGLATVATVVASQAVISGAFSVTRQAVQLGFWPRMQILHTSAVEKGQIYLPQVNALLLCAVLVLVITFRNSENLAAAYGFAVTGTMLMTSILAFAVLPRGSTGAKRLGWMLVLGVLLIIDVLLFSANIFKIHEGGWMPLLVGVVVFTLMMTWRRGRQLLADIQARDRQPLQEFMDQLESYPPARVPGTAVFMTLNNDNVPPALLHNLKHNKVLHDHVLFLSIRVADVPYIAEQDRFSVKRVSASSWQAVIHYGFKEDPDVPEALRLVAEAYPEIDLEPMRTSFFLSRQAVVAARRPAMSRWRRTVFSFMARNSTRSTKFFKIPPNRVVEMGMQIEL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PD1_MOUSE
Sequence: MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPEDTFIVGYARSRLTVDDIRKQSEPFFKATPEERPKLEEFFARNSYVAGQYDDAASYKHLNSHMNALHQGMQANRLFYLALPPTVYEAVTKNIQETCMSQTGWNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPATTGSDDVRDEKVKVLKCISEVETDNVVLGQYVGNPNGEGEAANGYLDDPTVPHGSTTATFAAAVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHKIDREKPQPIPYVYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase X, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: P21_SOYBN
Sequence: ARFEITNRCTYTVWAASVPVGGGVQLNPGQSWSVDVPAGTKGARVWARTGCNFDGSGRGGCQTGDCGGVLDCKAYGAPPNTLAEYGLNGFNNLDFFDISLVDGFNVPMDFSPTSNGCTRGISCTADINGQCPSELKTQGGCNNPCTVFKTDQYCCNSGSCGPTDYSRFFKQRCPDAYSYPKDDPPSTFTCNGGTDYRVVFCP
What are the official names of this protein?
Protein P21.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: MYH6_MOUSE
Sequence: MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKKMHDEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-6, Myosin heavy chain 6, Myosin heavy chain, cardiac muscle alpha isoform, MyHC-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: UGTP_BACC3
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLKAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQDTNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPAGHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.