PharMolix/UniProtQA huggingface dataset:
Protein: ISCA_YERPG
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ACYP_STAA1
Sequence: MRHIHLQVFGRVQGVGFRYFTQRIAMNYNIVGTVQNVDDYVEIYAQGDDADIERFIQGVIEGASPASNVTSHQLEELELNQKLSDFRSI
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: OBG_RHIL3
Sequence: MKFLDEAKVYIKSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVEAVNGLNTLIDFRYQQHFKATIGTHGMGRNRTGANGSDVTLKVPVGTQIFEEDQETLICDLTVEGQRYCLAHGGNGGFGNAHFKTSTNQAPDWANPGLPGEEKTIWLHLKLIADAGLVGLPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVLLHLISAQEEKVGKAYKTVKHELEAYGNELTDKAEIVALSQIDVLDDAELKKKTKELAKACGKTPFQISAVTGKGMTEVLRALRDIIVEANTEEKPAKVPKLRHRDMVVTDEGEDKGGDEGDDQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_CHLPD
Sequence: MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDNLPAMLASGVPVVVGTTGWDDAMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLIAPFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRKRTIVRQLSDNRKLAAEELQVASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMDDFLNERLS
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I80AC
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQEMGDAPFLDRIRRDQKSLKGRSITLGIDIEAATRAGKLIIERILDEESDEALKMNIASVPASRYVTDMTPEEMSRDWFMLMPKQKFAGPLCIRMDQAILDKNIVLKANFSVAFDRLETLILLRAFTSEGAIVGEISQLPSLPGHTSEDVKNAIGILIGGLEWNDNTVRVSETLQRFAWGSSNENGRPPFAPKQERKMAGTVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: NTF7_DANRE
Sequence: MRSLTLVLLILISIQAALIMGGHTQAQASANQHAATQNSPRLYSQSKEDLHYDELIPTVDPKLFNKRRYRSPRVVFSDVITAEKEMGTPRRPRIRRKANDFLHRGEYSVCDSEEHWVGNLTHATDLGGNEVMVLPHFRINNVVKKQLFYETTCRVKKPIGAPKPGQGASGVKAGTSSCRGIDSKHWNSYCTNTHTYVRALTSYKNQIAWRFIRINAACVCVLSRNSWRHGLKY
What is the function of this protein?
Recombinant ZNT-7 was able to bind to the human p75 neurotrophin receptor/NGFR and to induce tyrosine phosphorylation of the rat NTRK1/TRKA receptor tyrosine kinase, albeit less efficiently than rat NGF.  ZNT-7 did not interact with rat NTRK2/TRKB or NTRK3/TRKC, indicating a similar receptor specificity as NGF.
What are the official names of this protein?
Neurotrophin-7, NT-7, zNT-7.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS2_SHISS
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWADD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PSBN_ASPOF
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOK_RHOJR
Sequence: MNPENYLYLSALLFTIGAAGVLIRRNAIIVFMCIELMLNASNLAFVTFARMHGNLDGQVFAFFTMVVAAAEVVVGLAIIMTIFRSRRSASVDDANLLKN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCME_SHIFL
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: GYRB_ACIG6
Sequence: DNSYKVSGGLHGVGVSVVNALSKKLHLIIHRAGQTHEQEYCHGDSQYPLKVIGETDKSGTVIRFWPSELTFSQTIFSVEILARRLRELSFLNAGVRIVLRDERVNFEHVYDYEGGLSEFVKYINEGKTHLNEIFHFTTDTDSGIAVEVALQWNESYQENVRCFTNNIPQKDGGTHLAGFRAALTRGLNQYLESENILKKEKVAVTGDDAREGLTAIISVKVPDPKFSSQTKEKLVSSEVKPAVEQAMNKEFSAYLLENPQAAKSIAGKIIDAARARDAARKAREMTRRKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_SALCH
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAGLGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGVLPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLSAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNEGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVASRSYYGKGYQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSVDVAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: PRIO_CRIGR
Sequence: MANLSYWLLALFVATWTDVGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGTWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPMLHFGNDWEDRYYRENMNRYPNQVYYRPVDQYNNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCVTQYQKESQAYYDGRRSSAVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: DXR_CYAP4
Sequence: MKAITLLGSTGSIGTQTLDIVAQYPDQFRIVGLAAGRSLDKLIPQIRQFRPQIVALADEQQLDDLKAAIADLDPQPILVAGPAGVCEVAAYGDAKTVVTGIVGCAGLLPTIAAIKAGKDIALANKETLIAGGPVVLPLVEQYGVKLLPADSEHSAIFQCLQGVPAGGLRRILLTASGGAFRDWPVDKLGQVTIADALKHPNWSMGQKITVDSATLMNKGLEVIEAHYLFGLDYDHIEIIIHPQSIIHSLIEVQDTSVLAQLGWPDMRLPVLYAMSWPERIATDWPRLDLLKAGDLTFKEPDHAKYPCMKLAYAVGRAGGAMPAVLNAANEQAVALFLAERIAFLDIPRLIEQTCDRFSSKNCAEPSLEDILAADQWARQEVLLASQN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ATPF2_GLOVI
Sequence: MDMLFDPGWAAHLLLLAAEEAAAAEAESGGLFDFGGTLVLQIVNFLLLMTILSAVFYGPISRVIEERSEYIRSNAGSAQRRFDEAKALADQYEQELRTTRLEAQQVIAAAEAEAQKIRAQQLAEAQREAQERIAQAQADLDKQKQAALASLSGEVEAISRTLSEKLLSDSARRF
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS17_DEIRA
Sequence: MKKTFTGVVVSDKADKTVSVKVERRFAHPLYGKVVTRSHKYAAHDENNEYKIGDRVEIIAVRPISKTKTWKVTKLIERPRGIETTLAETEVAGGEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MSRQ_PSEU2
Sequence: MRYPFLRLAVFLAACIAPVWWLYQAWIFALGPDPGKVLVENFGVATLVMLLITLSMTPLQRLTGWSGWIVVRRQLGLWCFAYALLHLSMYALFILGLDWGQLGVELVKRPYIIVGALALLGLLALAVTSNRYSQRRLGARWKKLHRIIYVILGLGLLHMFWIVRADLKEWALYAGIGAFLLLLRIPVFARRIPRLGGAAKARSVKVQNNG
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THI4_METBU
Sequence: MKLDEVTISRAIIEEFSKVFLDYTDVDVALVGGGPANLVAAKYLAEAGLKTVIYEKKLAVGGGMWAGGMMFPRIVVQEDALHILDEFGISYHEYENGYYVANSIESVGKLISGATSAGAEIFNLVNVEDVMIRENDEICGLVINWTAVEIGKLHVDPLAIRSKVVVDGTGHPAVVCSTVQRKVPGAKLGELGVVGEKPMWADVGEKMLLDTTKEVYPNLYVAGMAANAVAGAPRMGPVFGGMLLSGKQVAELIIERLG
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: DDL_FRATN
Sequence: MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKCFVALHGEDGENGRVSALLEMLEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLTDKLVAEDEISFPVAVKPSSGGSSIATFKVKSIQELKHAYEEASKYGEVMIEQWVTGKEITVAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGCSGHARVDFIYDDRGNFYIMEINSSPGMTENSLSPKSAAAEGVDFDSFVKRIIEQAQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_CUPPJ
Sequence: MTQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGPYASVGGVPQDMKYRNEPTRLDIGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIAHDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVRIGAHAMLGGASALVQDVPPFVIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALLAQADASAAEPLRAFLDFIAATQRGIVR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_COXBR
Sequence: MNTIKILIGLLGIFLFSLSGIVSAQSDATTQLSQLLSNFRTYQAKFNQITFDGQDRVIQQSHGRVMIMRPGRFRWETDSPTKQIIITNGKTLWVYDVDLSQATQQPLAQKTNINPASLLSGSVKDLKQKFTITISPTPDAATFQLVPNLGKSLNFNWIRLKFSKKQLTEMTVLNNLDERSIFQFSQIKVNAPLSSTLFEFKPSRGIDVVKQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: EI3D1_DROGR
Sequence: MSETINTGAQFPTFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTSTSNNDKKYQNKYASTFGTGNQYAYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGLNTHGHGMTTLNSKNVKARDTRRGVGKRFGHRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGEDIATCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGEKIFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEAKYKFEETNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFLSIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDGEAFQQVYNYANNSNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_HAHCH
Sequence: MREKIRLVSSAGTGHFYTTTKNKRTMPEKMEIKKFDPVVRKHVAYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TBKB1_RAT
Sequence: MESMFEDDISILTQEALGPSEVWLDGPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLITDFGEEHGFPLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELGEMRALVETHLRQICGLEKQLQQQQGLRDAAFSSLSPPAVPATACPDLDLHYLALRGGPALGHAGWPGPTSVSVSELERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSECGMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAGQRHSPLSQRHSPAPACPSPSPPARPPPCAPCQSPAAQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPGERTLAERAYAKPPSHHAKAGFQGRRSYSELAEGAAYAAASPAWLQAEAATLPKPRAYGGELYGPGRPLSPRRAFEGIRLRFEKQPSEEEEWAMPASPPSPEASTIRCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
What is the function of this protein?
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.  Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus (By similarity).
What are the official names of this protein?
TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1, Protein ProSAPiP2.
Protein: RK5_CHAGL
Sequence: MVQRLKSIYLNNVIPKLNEEAKYKNVHQIPRLKKIVINCGIGEASQNAKTLEYTIRDLSIIAGQRPLVKRAKKAIASFQLRKKMPVGVSVTLRGDAMYAFLDRLINLALPRIRDFQGLNRKSFDGHGNFHLGLKEQLMFPEIDYDKIDKLRGMDICIVTTCTNDNECFQFLSALGMPFQTVSSKKL
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NEDD8_DROME
Sequence: MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDSILTPCV
What is the function of this protein?
Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis.  Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M.  Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
What are the official names of this protein?
NEDD8, Neddylin, Ubiquitin-like protein Nedd8.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSGA_BUCAP
Sequence: MQNINQIKLTWISFFSYAFTGALIVITGMIMGDIADYFNLSVSEMSNIFTFLNAGILISIFLNSWLIDLISIKKQLIFGFLFSIIAILGIVFSTSILLFSINIFILGLVSGITMSIGTFIITCLYSGEKRGSQLLLTDSFFSMSGMIFPIISAYLLDRKILWYWIYVFLGIIYFLIFILTVKSHFPVSEEKTKNNNEIKNLNINIILLSISALLYILGQLSFISWVPQYTTEIININIKKTGVLVSNFWMAYMIGMWCFSFIIKFFNLQRMFIFLTGSSSVLMYCFIYSKSYLALKYTIISLGFFSSAIYTIIITLASLETKKPSAKLINLILFFGTIGTLLTFIITSPIVAKKGLYTTLIFSNVLYVIVFFLSCIIFKNSKKKDHC
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUB_PYRIL
Sequence: MKCGNREIFVKTQESTNPEWGKPPSKRTTEEYIRYSLVLIDKPRGPSSHEVAAWVKKILGVERAGHAGTLDPKVSGVLPIAVAEGTKALLALSRSDKVYVAVAKFHGDVDEEKLKAVLNEFQGVIYQKPPLRSSVKRQLRTRHVYSLELLELDGRYAVIKMHVEAGTYARKLIHDIGEVLGVGANMRELRRIAVSCYTEDETVALQDVADAYYIWRRYGDDTYLRRVLLPIEEIARHLPKIWVRDSAVDALCNGAPLAAPGVVKFETPFSKGELVAFFTLKDELIGFGRALVESEEAKKMERGLVARVDRVIMRRGTYPPMWKRKQQT
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.