PharMolix/UniProtQA huggingface dataset:
Protein: RBL_HAPHI
Sequence: DPDYAIKETDILALFRCTPQPGVDPVEAAAALAGESSTATWTVVWTDLLTACDLYRAKAYRVDPVPSTPDTYFCYVAYDIDLFEEGSLANLTASIIGNIFGFKAVKALRLEDMRFPVALLKTYQGPATGLIVERERMDKFGRPLLGATVKPKLGLSGKNYGRVVFEGLKGGLDFLKDDENINSQPFMRYRERFLYSMEGVNHAAALSGEVKGHYLNTTAATMEDMYERANFAKELGSIIVMIDLVIGYTAIQSMGKWSRDYDMILHLHRAGNSTYSRQKNHGMNFRVICKWMRMAGVDHIHAGTVVGKLEGDPLMIKGFYNTLLDFKSEVNLPEGLFFAQDWASLRKCVPVASGGIHCGQMHQLINYLGDDCVMQFGGGTIGHPDGIQSGATANRVALECMVLARNEGRDYVAEGPQILRDAAKSCGPLQTALDLWKDITFNYASTDTADFVETPTANV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FENR_STAAT
Sequence: MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDRHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTSIPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEANKTIVNKHLY
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: DPO3A_PASMU
Sequence: MSEPRFVHLRVHSDFSMINGIAKVKPLIKACVDNHMVAMGLTDFTNFCGLVRFYGEALSAGVKPIIGADVLVRSELCGDEPFELTLLAKNNIGYHNITLLLSKAYERGYQDLPYLDQAWLAEHREGIIVLSGGHNGDVGKKLLKGHAAEIESAVAFYQDFFPDHFYLSLSRTGRYEEERYVSLALTLAEEKGLPVVATNDVLFLHEDDFEAHEIRVAIHDSYTLDDPKRPKLYTNQQYFRSEQEMCDLFADVPSALENTLLIAQRCNVTIRLGEYFLPQFPTGDLSTEDFLVKKSKEGLEERLKFLFPDEKVRQARRPEYDERLQVELDVINQMGFPGYFLIVMEFIQWSKDNDIPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMDGRDRVIDHVAETYGRGAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFAAEPQLQAVYDSDEEVKALIDMARKLEGVTRNAGKHAGGVVISPGLITDFSPLYCDSEGKHPVTHFDKNDVEYAGLVKFDFLGLRTLTIIKWALDMINTRLAKEGKPPVDIATIPLDDPASFELLKRSETTAVFQLESRGMKDLIKRLQPDCFEDIIALVALFRPGPLESGMVQNFIDRKHGNEVVAYPDPEYQHDSLKPILEPTYGVIVYQEQVMQIAQELAGYTLGGADLLRRAMGKKKPEEMAAQREIFEKGAIQKGVDGELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKTHYPAEFMAAVMTSEMDNTDKIVGLYDECLRMGLKVAPPDINTGKHHFSVNEYGEIVYGIGAIKGVGEGPIEALISAREQGGIFKDLFDLCARVDLKKINRRTFESLILSGAFDKLGPHRAALSKNLEDALKASDQHAKDAAMGQADMFGVLTESHEDVEKAYASTPRWSEKVILEGERETLGLYLSSHPISPYLKELAHYSATRLKDLVPNSRGQMSTVSGLLVSSRFAVTKKGNRLGIATLDDRSGRLDITLFGEALDKYADKLQKDTVIIVSGQVSFDEFSGGLKMSVRELMSLDEARSRYAKSLAICLSEENMKPTFIRELKALLTPYSGGTLPIYVYYASTAGQCRVKMGVQWSVNPTDQLFTELAEKLGENAVELEFQS
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_LACLA
Sequence: MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKHRVKMLELAIKENPRLGLELIEIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPKWYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPISSTMLREMFAKNIEPTYFLPQNVIDYIKTEKLYKKR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SECY2_STAAN
Sequence: MLKLLQQYEYKIIYKRMLYTCFILFIYILGTNISIVSYNDMQVKHESFFKIAISNMGGDVNTLNIFTLGLVPWLTSMIILMLISYRNMDKYMKQTSLEKHYKERILTLILSVIQSYFVIHEYVSKERVHQDNIYLTILILVTGTMLLVWLADKNSRYGIAGPMPIVMVSIIKSMMHQKMEYIDASHIVIALLIILVIITLFILLFIELVEVRIPYIDLMNVSATNMKSYLSWKVNPAGSITLMMSISAFVFLKSGIHFILSMFNKSISDDMPMLTFDSPVGISVYLVIQMLLGYFLSRFLINTKQKSKDFLKSGNYFSGVKPGKDTERYLNYQARRVCWFGSALVTVIIGIPLYFTLFVPHLSTEIYFSVQLIVLVYISINIAETIRTYLYFDKYKPFLNQYW
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins.  The central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CARS_PSEAE
Sequence: MRSIQRRLSVGLFAVLLVVGLVLAQTGLWLFDQGLRRYFAGNLREEAENLLVAMVRGPNGMQLDEQRLNPAFQRPYSGRYFVIELEKDTWRSRSLWDSELEVPHKKGLVQGLVDGPEEQRLLVFRGHYKRMGQKLRIVVAQDYTPILESFARVQWMGLGAGALALLLVLLLQRLTVRRSLRPLEEVRLQIAQLQQGQRSQLDNQAPEELEPLVEQINHLLAHTEETLKRSRNALGNLGHALKTPLAVLVSLAEREEMARQPELQQVLREQLEQIQQRLGRELGKARLVGEALPGAHFDCAEELPSLCDTLRLIHGPHLQVSWSAPPGLRLPWDREDLLEMLGNLLDNACKWADSEVRLTVAQGEGMVRLKVDDDGPGILPDQRQAVLERGTRLDEQVSGHGLGLGIARDIAEACGGRLSLEDSPLGGLRVSVELPLQKSGRAARA
What is the function of this protein?
Member of the two-component regulatory system CarS/CarR that regulates the expression of multiple genes involved in calcium signaling and homeostasis including CarO and CarP (PubMed:26755627).  May function as a membrane-associated protein kinase that phosphorylates CarR in response to environmental signals leading to activation of specific gene promoters (Probable).
What are the official names of this protein?
Sensor protein kinase CarS.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ILVD_PSEFS
Sequence: MPDYRSKTSTHGRNMAGARALWRATGMKDDDFKKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDKITPGMLMAALRLNIPVIFVSGGPMEAGKTKLASHGLDLVDAMVIAADSSASDEKVAEYERSACPTCGSCSGMFTANSMNCLVEALGLALPGNGSTLATHSDREQLFLQAGRTIVELCKRYYGENDESVLPRNIANFKAFENAMTLDIAMGGSTNTILHLLAAAQEAEIDFDLRDIDRLSRHVPQLCKVAPNIQKYHMEDVHRAGGIFSILGSLARGGLLHTDLPTVHSKSIAEGIAKWDITQTDDEAVHTFFKAGPAGIPTQTAFSQSTRWDTLDDDRENGCIRSVEHAYSQEGGLAVLYGNIALDGCVVKTAGVDESIHVFEGRAKIYESQDSSVRGILADEVKEGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVQDGDKVLIDIPNRSINLLISDEELAARRVEQDKKGWKPVEKRPRKVTTALKAYALLATSADKGAVRNKAMLDGL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: FABR_SALAR
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SHEFN
Sequence: MSRVAKAPVTVPAGVEVTLNEQTLTVKGSKGSLTRVINNAVNVVIEDAQVKFLPVDGVSNAWAQAGTARALVNNMVVGVSQGFVKKLKLVGVGYRAKIAGSDLDLTLGFSHPLVHKLPAGVTAECPSQTEIVLSGVDKQVVGQVAAEIRGYRPPEPYKGKGVRYDDEIVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PAGP_YERPB
Sequence: MNYKDIINACILSGVFLLHSPSALADTPSVGVSKGQESLQPAAEGNLWQRLIRNVSLAWNSPHQELYIPVNTWHNRWTYDDEKIASYNERPWGVGYGKYRYDEDNNWHSVYAMAFMDSHNRVEPILGYGYQKMWIPGEREGWRFGAGFTASITARYEYHYIPLPLPLPLISIEYNRLSLQTTYIPGTYNNGNVLFTWIRWQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RIMM_HAEIE
Sequence: MEQQHIEVVGKLGSTYGIRGWLRIYSSTEQAESIFDYQPWFLKIKGEWQSIELENWRYHNHEIIVKLKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWHDLIGCTVVNLEGYTMGTVTEMMETGSNDVLVVKANTKDAFGKQERLIPFLYEQVVKRVDLTTKTIEVDWDAGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_BURCM
Sequence: MPDRLVPATLARRDDGILVSPEYGELPRDASRARAHANRMLAGTGLLARWQGRRTFTIVETGFGTGGRFLATWAAWRDDPARCERLHFVAIEAHPFTREDLRRAVSHLVADTTISENADALIDAWPMHVPGLHRLEFDAGRVVLTLAFGDARDMLQRLVARADAFYLGNVASAAHGDVLSADVIRALARIAADGATYATHSHDDTVKHALEQTGFTSRDVEDCAGEPALRVGEYAPRWRMRRHEPPRALPVAAREAIVIGAGLAGCAVVERLAARGWNITLIERHERIASEASGNPAGVFHPLMTRDDNVASRLTRSGFLHALARWRALEDAGHAFARSTRGMIHLAESADDFARMRDAFDALGAPSDYVSLLDTDAARAHLNLPVAHGGLLFPHGGAVWPAGVCAAQIAAAGERVTLLAGTEVARLERDRDIWRAVDAAGATLAEAPVVVLANAGDAVRLAGLRHVALQPVRGQLTLLPPGSTAPLPCPTIGDGYAVPLDDGTLLIGATFEPDDVDRTMRTVGHIENLARVRHLLPGLIGELPDVDTLRGRVAFRWVVADRVPVIGPLADEAQAVANARALSGAKARDLPRTAGLYGAFGYGSRGLVWAALGAELIASQLEGEPLPLERELVDAVDPARFLIRALRGRQIG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_GEOKA
Sequence: MYLIPTVIEQTNRGERAYDIYSRLLKDRIVFLGSPIDDQVANSIVSQLLFLAAEDPDKDISLYINSPGGSITAGLAIYDTMQFIKPDVSTICIGMAASMGAFLLAAGAKGKRFALPNSEIMIHQPLGGAQGQATEIEIAAKRILFLRDKLNRILSENTGQPIEVIERDTDRDNFMTAQKAMEYGIIDRVLTRADEK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.  ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW.  This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4970_PHOPR
Sequence: MYSNKPSRKPHTFQFRGKQLQASDSLFFIIALLCLLPIISSPVALILGFTLASFGFVPTKLNIAAATKKLLAYSIIGLGFGIHLDQAIAASTQGFGLIVGSIFFTLIFGWFLTKALRLDQKTGHLIASGTAICGGSAIAAVAPAINARDDQTSLALATVFVLNSIALFIFPAIGHLLEMSQHAFGTWAAIAIHDTSSVVGAAGAYGDEALRTATTIKLARALWIVPIAFLSALLFKGDNKKIGIPYFILFYCLAIVFAHFVPSLESIYSHIFVASKRLLVVCLFLIGSGITIQKLRAAGLKPLLLGVLLWVAIGVGSLSYILLNVA
What are the official names of this protein?
UPF0324 membrane protein PBPRB0970.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDC10_CAEEL
Sequence: MNEEGGYLGAMTYQCLYSPVMEKIKQQHRDDPRASLALNKLHTALTTCEQASPSFLYDFTKVLLDDSELSVNLQESYLRMHDTSPTNDLIVSGYEQNADYKELTKRAIELRRVLSRVPEEMSDRHAFLETIKLIASSIKKLLEAINAVYRIVPLTAQPAVEKRKREFVHYSKRFSNTLKTYFKDQNANQVSVSANQLVFQTTMIVRTINEKLRRG
What is the function of this protein?
Involved in excretory canal elongation during postembryonic development.  Plays a role in promoting Golgi stability, ER integrity and vesicle transport probably by regulating the activation of Rho GTPase cdc-42.  Involved in fertility.
What are the official names of this protein?
Programmed cell death protein 10 homolog, Cerebral cavernous malformation protein 3.
What is the protein family that this protein belongs to?
Belongs to the PDCD10 family.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane; Peripheral membrane protein. Note=Co-localizes with gck-1 at the apical membrane of the excretory canals.
Protein: PNP_RHOPA
Sequence: MFNIHSVEIDWGGRPLKLETGKVARQADGAVVATYGETVVLATVVAAKAPREGVDFLPLTVDYQEKAYAAGRIPGGYFKREGRPTEKETLVSRLIDRPIRPLFADGWRNETQVIVTVLSHDMENDPDVLAMVAASAALTLSGVPFKGPIGAARVGFINDEYVLNPVLDEMAETQLELVVAGTADAVLMVESEAKELSEEIMLGAVMFGHRHFQPVIDAIIDLAEKAAKEPRELTVVDDSEIEKEMLGLVEQELRAAYAIPVKQDRYAAVGKVKEKAIAHFFPEGQEPKYDKLRIAGVFKELEAKIVRWNILDTGKRIDGRDSKTVRNILAQVGVLPRTHGSALFTRGETQAMVVTTLGTGEDEQYVDSLSGTYKETFLLHYNFPPYSVGETGRLGGTKRREIGHGKLAWRAIHPVLPPHHEFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPLKRPTAGIAMGLILEGERFAVLSDILGDEDHLGDMDFKVAGTEAGITSLQMDIKIAGITEEIMKVALGQAKDGRIHILGEMSKALDRARAELGEHAPRIETFKIPTDKIREVIGTGGKVIREIVEKTGAKVNIEDDGTVKVASSDGESIKAAIKWIKSIASDPEVGEIYEGTVVKVMEFGAFVNFFGAKDGLVHISQLAAGRVQKTSDVVKEGDKVKVKLLGFDDRGKTRLSMKVVDQTTGEDLEAKQKAEAKAEGEAPAQAAGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS1_CHLTR
Sequence: MPKQADYTWGAKKNLDTIACLPEDVKQFKDLLYAMYGFTATEEEPTSEVHPGAILKGTVVDISKDFVVVDVGLKSEGVIPMSEFIDSSEGLTVGAEVEVYLDQTEDDEGKVVLSREKATRQRQWEYILAHCEEGSIVKGQITRKVKGGLIVDIGMEAFLPGSQIDNKKIKNLDDYVGKVCEFKILKINVDRRNVVVSRRELLEAERISKKAELIEQITIGERRKGIVKNITDFGVFLDLDGIDGLLHITDMTWKRIRHPSEMVELNQELEVIILSVDKEKGRVALGLKQKEHNPWEDIEKKYPPGKRVRGKIVKLLPYGAFIEIEEGIEGLIHVSEMSWVKNIVDPNEVVNKGDEVEVVVLSIQKDEGKISLGLKQTKHNPWDNIEEKYPIGLRVTAEIKNLTNYGAFVELEPGIEGLIHISDMSWIKKVSHPSELFKKGNTVEAVILSVDKESKKITLGVKQLTPNPWDEIEVMFPVGSDISGVVTKITAFGAFVELQNGIEGLIHVSELSEKPFAKIEDVLSIGDKVSAKVIKLDPDHKKVSLSIKEFLVHGGDAGHDAEEESSDRD
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: SYE_ROSCS
Sequence: MGVIQGPVRVRFAPSPTGYLHIGGVRTALFNWLFARHYGGQFILRIEDTDEKRYVPGSADDLMASLRWVGIEWDEGPDIGGPHAPYVQSLRYEAGIYRPFVEQLLESGHAYLSFTTEEELERMRAEAQARGVKAFRFRGPERDWPLDRQREMAATGRPYTVRLKTPTEGVTAFRDLVRGGERIEFKNEELYDIVLVKSSGMPVYHLAHLVDDHLMRMTHVLRSDEWVASTPYHVLLYQAFGWDPPAFAHLPPILRQDGRGKLSKRTDDVAANRFWERGYLPDAMFNYLALQGWSYDGYTEIMSREELIERFTLDRVQPSPARWNPEKLLDMNGIYIRRLTTEQLVDAMAPFLARAGLIGNPPTPDERAYLLQLAPLIHERLKELGEAPELLEFFFRDVTDYDPQALIPKKMDASTTVAALQAARDRLASLEPWTHDRLEAELRALGEELGLKPGQLFGALRVAATGRTVAPPLFDTLAALGKPRTLRRLEAAISVLAAAHAEVKGQS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVV_MONPV
Sequence: METSTSSSQSLIPLPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERRIAQDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSAAKVICVSPVMSGNSYRDRKKRSVEAFLDWMDTFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTPYNRCKYRNYIKKM
What is the function of this protein?
Plays a role in DNA replication by cleaving viral DNA concatamers to yield unit-length viral genomes.  The concatamer junctions contain inverted repeat sequences that can be extruded as cruciforms, yielding Holliday junctions that A22 protein cleaves.
What are the official names of this protein?
Resolvase OPG149.
What is the protein family that this protein belongs to?
Belongs to the RuvC family. Poxviruses-type subfamily.
Protein: GLMU_CERS4
Sequence: MDRATVSLIVLAAGQGTRMNSDLPKVLHPLGAAPMLHHALRAGQSLEPERVVVVAGHGAEAVAKAARAFDESIEVVVQAEQLGTAHAVAQAAPLLADAPGEAVVLYGDTPFIRPETLERMLDLRSRHAVVVLGFEATDPGRYGRLVTRGEELDRIVEWKDATDEERTISLCNSGVICAEAGLLLALVSEVGNANAAGEYYLTDVVALARVRGLSAGVAICDEAETLGVNTRAQLAEAEAEFQKRARAAALEDGVTLTAPDTVFFALDTFLGRDAIVGPNVVFGPGVTVESGAEIRAFCHLEGCHISRGATVGPFARLRPGAELAEDVHVGNFVEIKNAVLDEGVKVGHLTYLGDAHVGEHTNIGAGTVTCNYDGVMKHRTEIGAHAFIGSDTMLVAPVTVGARAMTASGSVITENVPAEALALGRARQVTKPGMATRLMEMFRAAKAAKKKEAP
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRM4A_HUMAN
Sequence: MAVQLVPDSALGLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPILDGSESPPHQSTDE
What is the function of this protein?
Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity).  Plays a redundant role with FRMD4B in epithelial polarization (By similarity).  May regulate MAPT secretion by activating ARF6-signaling (PubMed:27044754).
What are the official names of this protein?
FERM domain-containing protein 4A.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, tight junction. Note=Colocalized with CYTH1 at adherens junction and tight junction. Colocalized with PARD3 during the process of epithelial polarization.
Protein: GUC2A_MOUSE
Sequence: MNACVLSVLCLLGALAVLVEGVTVQDGDLSFPLESVKKLKGLREVQEPRLVSHKKFAPRLLQPVAPQLCSSHSALPEALRPVCEKPNAEEILQRLEAIAQDPNTCEICAYAACTGC
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
What are the official names of this protein?
Guanylin, Guanylate cyclase activator 2A.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCD83_MACFA
Sequence: MENSGKANKKDTHDGPPKEVKLPTSEALLDYQCQIKENAVERFMFQIKTLREKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDARKKITKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELENAIHELEAENLVLIDQLFNCRLVDLKIPRRLYLTQAAGLEVPPEEMPLELPETHIEEKSELQPIEVESRDLMSSSDESSTLHISHENSIEDLQYVKTDKEENSCTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSVESKKMPIHFQEKEIPVKLYKDVRSPESRITYKMMKSFL
What are the official names of this protein?
Coiled-coil domain-containing protein 83.
Protein: RS17E_SULIM
Sequence: MGNIYTKDIKRIVKEIYNQYKDEIKDDYNTNKQIVVRYVDVKSKKVRNRIAGYLTRYYKIMKEKETSPTEEKEEISEEI
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: NDUS2_NEPOL
Sequence: MAIEHASSIKKVKNFTLNFGPQHPAAHGVLRLVLELNGEVVARADPHIGLLHRGTEKLIEYKTYTQALPYFDRLDYVSMMCQEHAYSLAVEKLLHCEVPERAQYIRVLFSEITRILNHLLALTTHAMDVGALTPFLWAFEEREKLIEFYERVSGSRMHAAYIRPGGVACDLPANLCEDIYLFCQQFASRIDEMEEMLTNNRIWKQRLVDIGIVTAENAFAWGFSGVLLRGSGVAWDLRKTQPYDVYNRMIFDVPVGTQGDCYDRYLCRVEEMRQSIHIIMQCLNQLPKGMIKADDKKITPPSRSQMKQSMESLIHHFKLFTEGYTVPNSETYTSVEAPKGEFGVYLVSNGTNRPYRCKIRAPGFLHLQGLDMMSKNHMLADVVTIIGTQDIVFGEVDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  Component of the iron-sulfur (IP) fragment of the enzyme (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, NADH dehydrogenase subunit 7.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion.