PharMolix/UniProtQA huggingface dataset:
Protein: OGT_SULIL
Sequence: MLVYGLYKSPLGYITVAKDDKGFIMLDFCDCVEGNSRDDSSFTEFFHKLDLYFEGKPINLREPINLKTYPFRLSVFKEVMKIPWGKVMTYKQIADSLGTSPRAVGMALSKNPILLIIPCHRVIAENGIGGYSRGVKLKRALLELEGVKIPE
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAV_ENTAG
Sequence: MATIGIFFGSDTGQTRKVAKLIHQKLDGIADAPLDVRRATREQFLSYPVLLLGTPTLGDGELPGVEAGSQYDSWQEFTNTLSEADLTGKTVALFGLGDQLNYSKNFVSAMRILYDLVIARGACVVGNWPREGYKFSFSAALLENNEFVGLPLDQENQYDLTEERIDSWLEKLKPAVL
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.  NifF is the electron donor to nitrogenase.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: CE162_HUMAN
Sequence: MANCSQEELDEEFEQFMKELSDDSFENSDKTARQSKKEMKKKDTVPWWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY
What is the function of this protein?
Required to promote assembly of the transition zone in primary cilia.  Acts by specifically recognizing and binding the axonemal microtubule.  Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base.  Required to mediate CEP290 association with microtubules.
What are the official names of this protein?
Centrosomal protein of 162 kDa, Cep162, Protein QN1 homolog.
What is the protein family that this protein belongs to?
Belongs to the CEP162 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Localizes to the distal end of centrioles throughout the cell cycle. During ciliogenesis, found at the cilia base. Localizes to spindle microtubules during mitosis.
Protein: XGPT_CERS4
Sequence: MKERLPHEKGFHVSWDQIHRDSRALAWRLDGQGPDNGSWRAVVGITRGGLVPAMIVSRELDIRTVDTISVKSYNWQEQQAPTVIKAPQAELMGDGHGILIVDDLVDSGKTLELVRTLYPRAHFATVYAKPSGRPMVDTYITEVSQDTWIFFPWDMALQYVEPYRGRD
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH602_RHOJR
Sequence: MSKQIEFNEVARRSLERGVDKLADAVKVTLGPRGRHVVLAKAFGGPTVTNDGVSIAREIELEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQAIVRGGLKNIAAGANPMALGIGINAAADKVVEALLAAAKPVEGKTSIAQVATVSSRDEEIGEMVGEALTRVGTDGVVTVEESSTLATELVITEGVQFDKGYLSPYFVTDLDAQKAVYEDALVLLYREKITSLPDFLPLLEKVAESGKPLLIIAEDVEGEVLSTLVVNSIRKTIKAVAVKAPFFGDRRKAFLDDLAVVTGGTVINSDVGLTLKDAGLDLLGSARRVVVSKDETTIVDGAGTDDDIKGRVAQLRREIENTDSDWDREKLEERLAKLAGGVAVIKVGAATETDLKERKFRVEDAVNAAKAAVAEGIVPGGGSALVQASTELADNLGLTGDEATGVKVVREALQAPLYWIASNAGLDGSVVTSKVAEQPKGHGFNAATLTYGDLLADGVVDPVKVTRSAVVNAASVARMILTTESAVVEKPAEENEQQTGHGHSH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB_CUPMC
Sequence: MMHTHPVEQAALAWLDANLARRDAARPAARASHGVGGIALHVEQVVKRYNGREVLHGVNLRAAPGEFVAIVGRSGCGKSTLLRLVAGLESADAGAVALDGQPGGTPSSVRVMFQDARLLPWKRVLDNVAIGLPRERHADAAALLDQVGLADRANEWPARLSGGQRQRVALARALVHHPRLLLLDEPLGALDALTRIEMQALIESLWRRLGFTALLVTHDVSEAIALADRVVLIEDGRITLDQQVTLARPRQRGTADFAQIEDTVLRRVMRQESPAASDAELHFRSAEEFLS
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYW_PROMM
Sequence: MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEESLSTAALYLACGMDPDLCSIFVQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDNVSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDIAQQRINARFGSEEKPVLKVPDPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGNPDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMGDRIELIRVLDQGRTRAEETAQATLQRVRQALGFLIAS
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_BURP6
Sequence: MTVQQRRRLPIASRETLQALLSEGAQALGVALSDAQRGALLDYVALLAKWNAVYNLTAIRDPRQMLIQHILDSLSIVPHLGAHGAAAAALDVGSGGGLPGVVLAIALPGWRVTLNDIVHKKSAFQNQAKAELKLGNLSVVTGRVETLRSGADVPAKFDVIVSRAFADLADFVTLARHLVAPGGSIWAMKGVRPDEEIGRLPDGACVKQMIRLTVPSLDAERHLIEVELDEAI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_BETVU
Sequence: MIVREWLFFTMAPCDAAEPWQLGFQDAATPMMQGIIDLHHDIFFFLILILVFVSWILVRALWHFHYKKNPIPQRIVHGTTIEIIRTIFPSIILMFIAIPSFALLYSMDEVVVDPAITIKAIGHQWYRSYEYSDYNSSDEQSLTFDSYTIPEDDPELGQSRLLEVDNRVVVPAKTHIRIIVTSADVLHSWAVPSSGVKCDAVPGRLNQTSILVQREGVYYGQCSEICGTNHAFMPIVVEAVSRKDYGSRVSNQLIPQTGEA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TERM_BPB03
Sequence: MARNSRIRITNNDKALYAKLVKNTKAKISRTKKKYGIDLSNEIELPPLESFQTRKEFNEWKRKQESFTNRANQNYQFVKNKYGIVASKAKINEIEKNTKEAQRIVDEQREEIEDKPFISGGKQQGTVGQRMQILSPSQVTGVSRPSDFNFDDVRSYARLRTLEEGMAEKASPDYYDRRMAQMHQNFIEIVEKSFNSYWLTDELVERLKKIPPDDFFELYLIFDEISFEYFDSEGEDVEASEAMLNKIHSYLDRYERGDVNLDLKGF
What is the function of this protein?
Hydrolyzes host peptidoglycans during virus entry.
What are the official names of this protein?
DNA terminal protein, Gene product 3, gp3, Protein p3.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus DNA terminal protein family.
What are the subcellular locations of this protein?
Virion. Note=Associates with the host bacterial nucleoid through its N-terminal region.
Protein: AROC_CUPMC
Sequence: MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQEADQVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDYRGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQLGEVEVPFTDWKHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAVKGVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRTARESIDKAGSPASVETFGRHDPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPRIPAQAPGKS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ARGR_CHLPN
Sequence: MKKKVTIDEALKEILRLEGAATQEELCAKLLAQGFATTQSSVSRWLRKIQAVKVAGERGARYSLPSSTEKTTTRHLVLSIRHNASLIVIRTVPGSASWIAALLDQGLKDEILGTLAGDDTIFVTPIDEGRLPLLMVSIANLLQVFLD
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PH4H_DROME
Sequence: MYQRQVSFDKPTRVEDSAYIVEGVDIKEARNTCLLFSPKDSSLSSGALANILAIFKKHDINLVHIESRSSLRVPGYEFFVEADGKSGALGKAIEDVKEQCSYFNIISRDYKDNATAVPWFPRRIRDLDRFANQILSYGSELDADHPGFTDPEYRKRRKYFADIAYNYKHGEPLPHVDYTKEEIETWGIIFRNLTKLYKTHACREYNHVFPLLVDNCGFREDNIPQLEDVSNFLRDCTGFTLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHPSKPMYTPEPDVCHELMGHVPLFADPAFAQFSQEIGLASLGAPDDYIEKLSTIFWFTVEYGVCRQEGELKAYGAGLLSSYGELEYCLTDKPQLKDFEPEVTGVTKYPITQFQPLYYVADSFETAKEKTIKFANSIPRPFGVRYNAYTQSVEVLDSKPQISNLMDNINSEFQILQNAVAKLRV
What are the official names of this protein?
Protein henna, Phe-4-monooxygenase, Phenylalanine-4-hydroxylase, PAH, Tryptophan 5-hydroxylase, TRH, Tryptophan 5-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: RL17_CARGR
Sequence: MGRYSREPDVASKTCKARGSNLRVHFKNTRETAMAIKKMSLRRAQAFLKNVTDHKECVPFRRFNGGVGRCSQAKQWGTTQGRWPKKSAEFLLQMLRNAESNADYSGLDVDRLVIEHIQVNRAPCLRRRTYRAHGRINPYMSSPCHIEMWLTEAESGVDGAKQGKKKKKTDGVEKATTKRQKQ
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y2269_VIBVU
Sequence: MSDLKPKQVFEETIFSQQDKPELTAQQQFDQQQTFIPTTIEETEPELEDALEQVIRPSGRRKWLAGGLFAAFAGLVGWQAVDSVLSAMQNGDWLTLGWSGFISVLAGLGLGAMGKELWKLRQLRHLFSVQEQGEKLLQSDSVGQGKAFCQQVAKQSGVAEENPAYDRWKNSVNTAHSDAEILQMYDAMVVTQQDKQATKVISRFATESAALVAISPLAIADMLLVAWRNFKMIDTLSTIYGIELGYASRIRLLRLVLANMAVAGASELVIDAGMDLMSMDLAGKLSARAGQGVGVGILTARLGLKAMALLRPIPWQAETQVKLSAIRKEIVSKVASITLKP
What are the official names of this protein?
UPF0283 membrane protein VV1_2269.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFB_SYNC1
Sequence: MIVTYNWLKEFVDFEMSPDELAHRLTMAGLEVDSMDFIGEGLDSVVTARLVSVDKHPDADKLTVCQVDYGQDTVQVVCGATNHKAGDVVALATVGTVLPGDFKIKKSKIRGMESFGMLCSEKELGLAQDSDGIMILSPDCEPGQPVFEVLGLKDVRYELGLTPNRPDCLSVLGVAREVSAMCGRSLNVNLPPLSEGDESTRALTSVTIEDAEYCPRYAARLIRGVKVGPSPDWLVRKLESVGQRSVNNVVDVTNFILMELGHPLHAFDYQRLAEGRIVVKRAASKEQFTTLDSVSRSLEKSDLVICDGQGAVALAGVMGGENSEVVAETVDILLESAYFNPLAIRRTSKRLSLRSEASHRFERGADIAMVPVALDKAAALIVQVAGGVVCKGMIDEFPRPLAERKVTLAVQRVNEILGLKLGMDDIQAHLLSIGLEVQPVEEKDIDRLVVTIPSFRPDLERDIDLVEEVARLNGYDNIPVTMPAGRMLCHLPPQHLREVKRLRDVMVAAGFNETVNYSFVAPEAWDRLELSDDDPRREPVKILNPLTEDQSVMRTSLVPSLLECVTRNVAYQNSDLHLFELRPVFLTHTDDVLPIEKWRLCAVLCGRREQEGWRQNDEKVDFYDLKGVVEQILDSFNVAKVTWDGSSSENFLHPGKSCTLKQKKTVLGTLGEVHPKVLAAFDIDQPVYLLDLDFEQLLMAAGGHGGFSALSRFPQVARDSAFLVDEDIPFSEISEVLNRSTGKLVEDIVLFDVYRGKGIPEGKKSLAIRVRYRSDDRTLKDEEIQKAHDKIVKALIAKLGAEIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_LACPL
Sequence: MANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDDLLPEAFATAREGAKRVLGLYPFHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAISGKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKSPEEKRAAYNADITYSTNGEIGFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRFAKTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIMLKDKDYVISDGQALIVDSFTGRIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNLFRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIRDDRSDLLYPTLQSKFNAVVKEIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAVTIATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMLRFGSERIKNFLQRMNVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQYDDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERTVQLHMQGDAKDWDLDAVVDFAQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRVVDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSEIRQNIQR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SPEB_CHRVO
Sequence: MSDEMIYGDGAIRRQGLYGSSIENTYAGVLSFMRRNYSRDLEGVDVAVSGIPLDLSVTFRSGARMGPQAIRAASVQLAELKPYPWGFDPFEDLAVVDYGDCWFDAHNPLTIKPSIIEHARTILASGAKMLTFGGDHYVTYPLLIAHAEKYGKPLALLHFDAHCDTWPDDSPDSLNHGTMFYKAVKEGLIDPKKSVQVGIRTWNDDFMGLNVLGAPWVHDNGVDATIAEIKKTIGDAPVYVTFDIDCLDPSAAPGTGTPVPGGLTTAQALKIIRNLGDLNIVGMDVVEVAPSYDQSEITAIAAAHIACDMLCLMRNKKVAGTL
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: TRMB_BACFN
Sequence: MGKNKLEKFADMASYPHVFEYPYSAVDNVPFDMKGKWHKEFFKNDNPIVLELGCGRGEYTVGLGRMFPDKNFIAVDIKGARMWTGATESFQTGMKNVAFLRTNIEIIDRFFAEGEVSEIWLTFSDPQMKKATKRLTSTYFMERYRKFLVSNGIIHLKTDSNFMFTYTKYMIEENGLPVEFITEDLYHSDLVDDILGIKTYYEQQWLDRGLSIKYIKFLLPQEGELREPDIEIELDSYRSYNRSKRSGLQTSK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TRUA_NITWN
Sequence: MPRYKLTIEYDGGPFCGWQYQTNGPSVQGALEAAVKAICGDDVRVHGAGRTDAGVHALAQVAHCDIARHFMPDRLRDGLNAHLRPHPIGVLEAEIVPDSFEARFSARRRHYIYRIANRRANLAIDVGRVWRVPRPLDTEAMHAAAQRLLGKHDFTTFRDTECQAKSPEKTLDQLDVIRNGDNVSIITSARSYLHSQVRSMVGSLVWVGHGRWNADDLSGALAARRREACGPVAPPDGLYLARVDYEGSIPLRQDR
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: IFT46_BOVIN
Sequence: MADNSSDEYEDENNKEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDDEEHGAPLEGAYDPADYEHLPVSAEVKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLAEYIDMICAILDIPVYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKTAFTPPSNSNSQAGDAETLTFS
What is the function of this protein?
Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia.  May play a role in chondrocyte maturation and skeletogenesis (By similarity).
What are the official names of this protein?
Intraflagellar transport protein 46 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT46 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Expression is concentrated at the cilium basal body but is also detected along the length of the cilium.
Protein: HSLU_PSEP1
Sequence: MSMTPREIVHELNRHIIGQDDAKRAVAIALRNRWRRMQLPAELRAEVTPKNILMIGPTGVGKTEIARRLAKLANAPFLKVEATKFTEVGYVGRDVESIIRDLADAALKMLREQEIIRVRHRAEDAAEDRILDALLPQARVTSFSEEAAQTSSDSNTRQLFRKRLREGQLDDKEIEIEVADAVGVEIAAPPGMEEMTNQLQSLFANMGKGKRKARKLKVKEALKMVRDEEASRLVNEEELKAKALEAVEQHGIVFIDEIDKVAKRGNVGGADVSREGVQRDLLPLIEGCTVNTKLGMVKTDHILFIASGAFHLSKPSDLVPELQGRLPIRVELKALTPEDFERILQEPHASLTEQYQALLKTEGLNIEFLADGIKRLAEIAYQVNEKTENIGARRLHTLLERLLEEVSFSAGDLASTHDEAPIQIDAAYVNSHLGELAQNEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBH2_HALH5
Sequence: MNKTELIHQVAERTQMSKKDAGEVVNTVFDVIAESLAQGDSVQLIGFGNFEVRERAARKGRNPQTGEEIDIAATKTPAFKAGKQLKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LPXH_HAEIG
Sequence: MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSNQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAKSNQDKQAKSQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ASNA_BACC7
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTVDYLQKTVLTIYGIFKDLEDHLFEKYPFLGKYLPEEIVFVTSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRAADYDDWKLNGDILFWHPVLQSSFELSSMGIRVDSKSLDEQLTKTGEDYKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA2_CAUVC
Sequence: MRRLIVLFAAALAVLGATAPALAAPKTETAVFAGGCFWCMEHDMQGVPGVLKVESGYTGGHLKNPTYRDVTSETSGHYEAVRVTYDPAKLDYGFLLYRYWRLVDPTDDGGQFCDRGPSYRPAVFVTPAQRPIAEKSRTEAAKRLKTGTMKTQILPAQTFYLAEEYHRDYAKRNKLNYFAYRTGCGRDARLKQVWGG
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA 2, Protein-methionine-S-oxide reductase 2, Peptide-methionine (S)-S-oxide reductase 2, Peptide Met(O) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: GCH1L_DEIRA
Sequence: MTVSPSSQTGRGEIGRDELVRWLGEYLRIGAYPDPSLNGLQIQGTDKIRRIAASVDTSLQTLQAAAESGADLLLVHHGLFWGRPLAITGPHYERVRTAIQADLNLYAAHIPLDAHPEVGNNAMIARALSLTDLQPFGDWQGHKIGVAGTLPRELGLQDFADRIQKLTGEICLVHGGGSPNIHRVGVTSGSGAGAIAEAAAMGLDTLLTGEPEHKYFHDSFEYGVNVIFAGHYETEVFGVRALAARIEDEFGIPWQFLNFPTGL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.