PharMolix/UniProtQA huggingface dataset:
Protein: PHLP2_HUMAN
Sequence: MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTTSSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKPCHMDRLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAMDSFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPVGFASTTTIKDAPKPATPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNAGGLDTALLPRPERRCSLHPTPTSGLFQRQPSSATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPPLIESSPTLCSEEHARGSCFGIRRQNSVNSGMLLPMSKDRMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEVPKRKTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQDSRLEPEPHEEDRTEPPEEFDTAL
What is the function of this protein?
Protein phosphatase involved in regulation of Akt and PKC signaling.  Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA.  Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes.  Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and decreases cell proliferation.  Also controls the phosphorylation of AKT3.  Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis (PubMed:20513427).  Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation (PubMed:21986499).  Inhibits cancer cell proliferation and may act as a tumor suppressor.  Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation.  Dephosphorylates RAF1 inhibiting its kinase activity (PubMed:24530606).
What are the official names of this protein?
PH domain leucine-rich repeat-containing protein phosphatase 2, PH domain leucine-rich repeat-containing protein phosphatase-like, PHLPP-like.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Note=In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus.
Protein: MCSB_CLOPE
Sequence: MVQWISPLDNSIVIASKVKILRNIKGIKFTKLLNEEEFNDLLSMVLGRLKEIDILDKCYVVKLKDGEEKIIDYYKENFGLIKYFENKDNLIFIMNKNGEFNILLNEEEHIGIECTNSGLSLREVYSKVDKLDDLIEEKIHYSFDSELGYLTSNIKNLGTALRTKVFIHLPLLSSNNLIRIIKNALKEEGITLKSIYNSGNKDVGNIYEVSNIKTLGMSEKDILDSLISITNKLILREKNQRDNLSKDEYIELKDDILRALGVLRNTYSIDRDEALKYLSYVRLGVELGIIEDLTLKPVNSAMIEIQPDMINNSSIKRRDIQSLKIERAKIIRNALNT
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: CAPSD_PMMVJ
Sequence: MAYTVSSANQLVYLGSVWADPLELQNLCTSALGNQFQTQQARTTVQQQFSDVWKTIPTATVRFPATGFKVFRYNAVLDSLVSALLGAFDTRNRIIEVENPQNPTTAETLDATRRVDDATVAIRASISNLMNELVRGTGMYNQALFESASGLTWATTP
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: MMK1_MEDSA
Sequence: MEGGGAPPADTVMSDAAPAPPQMGIENIPAVLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQSFQEKFPHVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEYQQ
What is the function of this protein?
May play a role in the mitogenic induction of symbiotic root nodules on Alfalfa by Rhizobium signal molecules.
What are the official names of this protein?
Mitogen-activated protein kinase homolog MMK1, MAP kinase ERK1, MAP kinase MSK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: RL14_DICNV
Sequence: MIQMQSRLSVADNSGARELQCIKVLGGSHRRYAGIGDVIKVSVKDAMPRGRVKKGDVYNALIVRTKKGVRRRDGSVLRFDGNAAVLLNSKLEPIGTRVFGPVARELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NSMA2_HUMAN
Sequence: MVLYTTPFPNSCLSALHCVSWALIFPCYWLVDRLAASFIPTTYEKRQRADDPCCLQLLCTALFTPIYLALLVASLPFAFLGFLFWSPLQSARRPYIYSRLEDKGLAGGAALLSEWKGTGPGKSFCFATANVCLLPDSLARVNNLFNTQARAKEIGQRIRNGAARPQIKIYIDSPTNTSISAASFSSLVSPQGGDGVARAVPGSIKRTASVEYKGDGGRHPGDEAANGPASGDPVDSSSPEDACIVRIGGEEGGRPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLVKGRAGPDTSASGEPGANSKLLYKASVVKKAAARRRRHPDEAFDHEVSAFFPANLDFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMDVAYHCYPNKCNDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHAPQEDSAIRCGQLDLLQDWLADFRKSTSSSSAANPEELVAFDVVCGDFNFDNCSSDDKLEQQHSLFTHYRDPCRLGPGEEKPWAIGTLLDTNGLYDEDVCTPDNLQKVLESEEGRREYLAFPTSKSSGQKGRKELLKGNGRRIDYMLHAEEGLCPDWKAEVEEFSFITQLSGLTDHLPVAMRLMVSSGEEEA
What is the function of this protein?
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine.  Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently.  Also hydrolyzes sphingosylphosphocholine.  Regulates the cell cycle by acting as a growth suppressor in confluent cells.  Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization (PubMed:10823942, PubMed:14741383, PubMed:15051724).  Binds to anionic phospholipids (APLs) such as phosphatidylserine (PS) and phosphatidic acid (PA) that modulate enzymatic activity and subcellular location.  May be involved in IL-1-beta-induced JNK activation in hepatocytes (By similarity).  May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF-kappa-B activation under inflammatory conditions (By similarity).
What are the official names of this protein?
Sphingomyelin phosphodiesterase 3, Neutral sphingomyelinase 2, nSMase-2, nSMase2, Neutral sphingomyelinase II.
What is the protein family that this protein belongs to?
Belongs to the neutral sphingomyelinase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Note=May localize to detergent-resistant subdomains of Golgi membranes of hypothalamic neurosecretory neurons (PubMed:10823942). Localizes to plasma membrane in confluent contact- inhaibited cells (PubMed:15051724).
Protein: RIMP_THET8
Sequence: MGVNPPFLCEGGGEVTVDLWQLVEEAVSPLGLDVLEVHFARGELLVRLERKDERPITVADLEEASRHIEAALDREDPIPGSYRLLVESPGPKRPLFTRRHFERFQGLKAKVPGPEGFTGRILRVEGEEVVFQVGDEERRLRIGTFRANLAEWPEEPR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BACVZ
Sequence: MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRYQRHFKAIRGEHGMSKNQHGRNADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGGRGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVIVHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKLQDDHPVFPISAVTREGLRDLLFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNITRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLLEFEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_BEUC1
Sequence: MAKPVLRKPKKKSNPLKSAKIEAIDYKDTVLLRKFISDRGKIRARRVTGVSVQEQRAIAKAVKNAREMALLPYSSSAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: DAPA_CHLL2
Sequence: MSTRLISGSAVALVTPFRQDCSVDTVALRQLVRFHIAAGTDIIIPCGTTGESPTLSMEEQSRIIRTVKEEAGEQIMVAAGAGTNATDHAVELAKNAEKAGASAILSVAPYYNKPSQEGIYQHYARIAEAVSVPIIIYNVPGRTGSNVAASTILRLARDFGNIAAVKEASDNMAQITELLEERPENFSVLTGEDMLILPFMAMGGDGVISVAANQVPSAVKRLVEAARTGRLDEARAINTRYRRLFRLNFIESNPVPVKYALALMGMIEEVYRLPLVPLADENKRILKEELQSLGLV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PELO_PICTO
Sequence: MKINIDEKLETTEILIETQDDLWYIKNILNPGDIIEGIAYRRLEKRNDLERSKSTERIPIKVKIKIENLDFQPFTDKIKILGIIIDGDFSGEHQSIMYGPGDTLKIYKNLNEAERDFLNEAVKNEYSSGMIFVSLDEEAADIYLMRSYSLQDMAHIESNKTGKRYDLKYNEKQYFLDIIKALKNIKNVFLLIVLGTGFEPEKLYNEIKKDPFFNNIDVKFYNTYDTGKSGVYNLLNSDATSNIIKESRMAKEKRILETFLRNLNSGLSVYGYDEINNYLDNGAIDTLIISEEKFKMPETRELLNKASGIKIYIISNYTEPGEIIRSFGGYCAILRYKIK
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_SHESM
Sequence: MARYFILAAALLLTACSSTSKKPIADDPFYAPVYPEAPPTKIAATGSIYQDSQAASLYSDIRAHKVGDIITIVLKEATQAKKSAGNQIKKGSDLSLDPIYAGGSNVSIGGVPLDLRYKDSMNTKRESDADQSNSLDGSISANVMQVLNNGNLVVRGEKWISINNGDEFIRVTGIVRSQDIKPDNTIDSTRMANARIQYSGTGTFADAQKVGWLSQFFMSDWWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PPO1_SPOLT
Sequence: MSDMSGDVVEHPKLLFDRPNEPLITPKGDNKAVFQLSEKLVPPEYANNGVELNDRFGDDATEKIPLKTLDSYPAFTKASQLPSDADFSLLLPKHQEMATEVIDAFMNVPLNQLQDFLSTCVYARANLNPQLFNYCYSVALMHRDDTKNVPIQNFAETFPSKFMDSQVFQRAREVTAVLPQNVPRIPIIIPRDYTATDLEEEHRLAYWREDIGVNLHHWHWHLVYPFTASQRSIVAKDRRGELFFHMHQQLIARYNCERLNHSLKRVKKFSNWREPIPEAYFPKLDSLTSARGWPPRQANMYWQDLNRPVDGLNITINDMERWRRNVEEAISTGRVTKADGSSAELDIDTLGNMLEASILSPNRELYGSIHNNGHSFAAYMHDPTHRYLESFGVIADEATTMRDPFFYRWHAWIDDTCQRHKESAYVRPYTRSELENPGVQVTSVSVETAGGQPNTLNTFWMSSDVDLSKGLDFSDRGAVYARFTYLNNRPFRYVININNTGSARRTTVRIFMAPKFDERNLVWSLADQRKMFIEMDRFVQPLNAGQNTITRNSTDSSVTIPFEQTFRDLSPQGSDPRRTSLAEFNFCGCGWPQHMLVPKGTEAGAAYQLFVMLSNYDLDSVDQPGGNQLSCVEASSFCGLKDKKYPDRRSMGFPFDRPSSIATNIEDFILPNMALQDITIRLSNVVEQNPRNPPSAV
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.  Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone (By similarity).  Catalyzes the oxidation of 4-methylcatechol (PubMed:16185666, PubMed:19557749).  Binds to the surface of hemocytes and is involved in hemocyte melanization (By similarity).
What are the official names of this protein?
Phenoloxidase 1, Prophenoloxidase 1, Slppo1.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: SETB1_DROPS
Sequence: MASESAAMDILDSAEASLNVASTALVEKEKKVQPATDETTPEKKAKMEIDAEMKDLTNDIPNSRKSQEKDPDALEDAKDPEADSSIELLCSPTPAEATDVDAMASKTESDNSVELLESPLKSPSSNDVNDEELLPLEEKEKPGPAKELEPKESEPDSKESSKSEALADSSIELISSPTSDDSLAKEKEVEVKEEHGQQAEAQVLQEIPRKADDSFKLQDDIAMEEDVPVPRSKAMQESKETQKTSKTTTKLEPLVDSIKDAIEDCINCNCKRLKKQYVLACVAILNFYKVPRKLKRSQYVCLDCYDTAVEMYEEYAGLLLAKQPLLLREFKQEQADFVTLDSSDEEEDEKTPEKPEFSKNVLDLIENELEDAIKKTLNKVEFSNQFNWSKTILQAKIERLAKKFEEVDLQLAQVQGLADKMHCSVYNSCQVVHKQLPPLDLHQNICPSDYKRLQQLPAAGDIVRPPIKIGETYYAVKNKAIASWVSVSVMEICDTTTGGGVTVKAYKIKYQHMPYPMMKTVAAKHLAYFDPPTVRLPIGTRVIAFFDGTLVGGKEKGVVQSAFYPGIIAEPLKQNNRFRYLIFYDDGYTQYVHHSDVRLVCQASEKVWEDVHPASRDFIQKYVERYAVDRPMVQCTKGQSMNTESNGTWLYARVIEVDCSLVLMQFEADKNHTEWIYRGSLRLAPVFKETQNSLNADCAIHQMRVPRRTEPFIRYTKEMESSNMQVDQQIRAIARKSTSKSGSPASTAAPPTGSSSSSAVRHLNNSTIYVDDDTRPKGQVVHFTAKRNMPPKIFKSHKCNPGCPFPMMHRLDSYSPLSKPLLSGWERMFMKQKTKRTVVYRGPCGRNLRNMAEVHNYLRLTNNVLNVDNFDFTPDLRCLAEYYIESTIVKEADISKGQEKMAIPLVNYYDNTLPPPCEYAKQRIPTEGVNLNLDEEFLVCCDCEDDCSDKESCACWQLTVTGVRYCNPKKPIEEIGYQYKRLHEGVLTGIYECNSRCKCKKNCLNRVVQHSLEMKLQVFKTSNRGWGLRCVNDIPKGAFVCIYAGHLLTEAKANEGGQDAGDEYFADLDYIEVAEQLKEGYESDVERADLDHEDDNYGPDAEDDDDFRPNNYYQKKKEKLRSSRSNSSSTQNTELDSQERTVISFNPNTDLDETVRENSVRRFFGKDQTPFIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVGFFASSHIRSGTELTWNYNYEVGVVPNKVLYCQCGAQNCRVRLL
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 in ovary.  H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones.  Plays a central role during oogenesis (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase eggless, SETDB1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YEJL_ECOLI
Sequence: MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: NU3C_ORYSA
Sequence: MFLLHEYDIFWAFLIIASLIPILAFWISALLAPVREGPEKLSSYESGIEPMGGAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGISVFIEAFIFVLILVVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS6_GEODF
Sequence: MRMYETIFIVQPDLGEEELKGISARVQEVIVSMKGELKRLEDWGARKLAYPIEKFNRGRYYYLRFDGDAALIAELERRLRLNDKIIRYQSVKLEKEAPAAAAIPAKVTEEEPVEAAPEAKVETTTEEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL18_TRYCC
Sequence: MGVDLTGVQKKKRVVRHHTYSTNPYIKLLIKLYKFLAQRTNSAFNKLVHQRLLKSRSNRAPISLSRIAVCMKRKSVWLEKGKKAPIAVIVGDVLDDVRMARIPALRVCALRFSKSARERITGAGGECLTFDQLAMVAPTGKNTFLLRGRKSGRESVKHFGAAGVPGSHAKPFTSNRGKERQRSSARRRAFRHK
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_BAUCH
Sequence: MTAEISAQYWAFAIFIISAIILCVLILTLSFLLGERKHIKVYSRDLPFESGINPVGNPKLHLSAKFYLIAIFFVLFDIEAFYLYAWSSVIREAGWLGFYEAIIFVSVLLSGLVYLVRIGALKWTPNHS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSP1_SCHPO
Sequence: MGSVNNEEKTLIEPQRLLRKNTWHPEVDDSEVPPSVFPEYPVHKAIQKTSDSFRKRNYSAGDYVIAPLGGEREGSSLTHSWTFQPGKHNQRLYSDNFQEAQRQWKRLQEWGEVKETKKIRKRFDRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPWTLDGLKDPEKWLQNTDPSTVSRVEVSTDEVASAISLVGRLRRKLGKLFRFRRPKARVFDSSSSVPSDSSICRPESSGNSSIGLSASELSDSFNRLAVNESQKDRERKQVHPVEMGRNSSEKKPRCDFGWDYEAFPNDNQDADDACSYNTGDSIPQVSKSINGHFETYSRTSMDTDDVASFESPNAKHEESGMPVVTFRNYENYDANPSNFHPVVPGFVSSPNLHLAGGSDTPIYCIEHSFTPTN
What is the function of this protein?
Involved in actin localization and thus in polarized cell growth.
What are the official names of this protein?
Serine/threonine-protein kinase ssp1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRPL1_RAT
Sequence: MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSVDIKKYQVLVGEPVRIKCALFYGYIRTNYTLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIKEVKEDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLVCSVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTALATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQRPQTKSSREPNPDEAHTNSAILPLLARETSISSVIW
What is the function of this protein?
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:17502602).  May activate the MAP kinase JNK (By similarity).  Plays a role in neurite outgrowth (PubMed:18801879).  During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
What are the official names of this protein?
Interleukin-1 receptor accessory protein-like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, X-linked interleukin-1 receptor accessory protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Note=May localize to the cell body and growth cones of dendrite-like processes.
Protein: GCSPA_GEOKA
Sequence: MLHRYLPMTEEDKQEMLKTIGVASIDDLFADIPEQVRFRGELKVKPAKSEPELWKELAALAEKNASVKQYVSFLGAGVYDHYIPAVVDHVLSRSEFYTAYTPYQPEISQGELQAIFEFQTMVCELTGMDVANSSMYDGGTALAEAVLLSAAHTKRKKVLISTAVHPQYREVVRTYAKGQKLEVKEIPYDGGITDLKALEAEMGDDVACVVVQYPNFFGQIEPLKAIAPLAHEKKSLFVVASNPLALGVLTPPGAFGADIVVGDMQPFGIPTQFGGPHCGYFAVKAPLMRKIPGRLVGQTTDEDGRRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVALSALGKRGVKEMAAMNIQKAHYAKVELEKRGLSSPFAGPFFNEFVIRLGRPVSDVNDRLLEKGIIGGYDLGADYPELAGHMLVAVTELRTKEEIDRFVNELGDGHA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.