PharMolix/UniProtQA huggingface dataset:
Protein: HIPA_ECOL6
Sequence: MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLSLPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVTLIPEDETVTCPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTALLRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVPDAEIIKAGRVRALAVKRFDRRWNTERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIAQIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDIISAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKXYPRHFXATAKVLKFPEVXMHEILXDFARMIPAALDNVKNSLPXDFPEXVVTAVETNVLRLHGRLSPEYXXK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Phosphorylates Glu-tRNA-ligase (GltX, on 'Ser-239') in vivo.  Phosphorylation of GltX prevents it from being charged, leading to an increase in uncharged tRNA(Glu).  This induces amino acid starvation and the stringent response via RelA/SpoT and increased ppGpp levels, which inhibits replication, transcription, translation and cell wall synthesis, reducing growth and leading to multidrug resistance and persistence.  Low level expression of HipA induces dormancy and depending on the protein level, can be toxic enough to reduce cell growth or even kill cells.  Low levels of wild-type HipA lead to high beta-lactam antibiotic tolerance of the survivor cells, also dependent on relA and relA/spoT.  The toxic effect of HipA is neutralized by its cognate antitoxin HipB.  With HipB acts as a corepressor for transcription of the hipBA promoter; binding to DNA induces a 70 degree bend (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase toxin HipA, Ser/Thr-protein kinase HipA, Toxin HipA.
What is the protein family that this protein belongs to?
Belongs to the HipA Ser/Thr kinase family.
Protein: GPMI_HELPH
Sequence: MAQKTLLIITDGIGYRKDSDHNAFFHAKKPTYDLMFKTLPYSLIDTHGLSVGLPEGQMGNSEVGHMCIGAGRVLYQDLVKISLSLQNDDLKNNPAFLNTIHKSPVVHLMGLMSDGGVHSHIEHFIALALECEKSHKKVCLHLITDGRDVAPKSALTYLKQMQNICNENIQIATISGRFYAMDRDKRFERIELAYHSLMGLNHTPLSPSEYIQSQYDKNITDEFITPACFKNYYGMQDDESFIFINFRNDRAREIVSALGQKEFSGFKRQAFKKLHIATMTPYDNTFPYPVLFPKESVQNTLAEVVSQHNLTQSHIAETEKYAHVTFFINGGVETPFKNENRVLIPSPKVTTYDLKPEMSAKEVTLAVLEQMKLGTDLIIVNFANGDMVGHTGNFEASVKAVEAVDACLGEILSLAKKLDYAMLLTSDHGNCEHMKDENQNPLTNHTAGSVYCFVLGDGVRSIKNGALNNIASSVLKLMGLKAPATMDEPLF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CP18A_DROME
Sequence: MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN
What is the function of this protein?
Probably involved in steroid hormones biosynthesis.
What are the official names of this protein?
Cytochrome P450 18a1, CYPXVIIIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: HPS1_MOUSE
Sequence: MKCVLVATEGAEVLFYWTDEEFAESLRLKLQQSEDEEEELPVLEDQLSTLLAPVIISSMTMLEKLSDTYTCFSTENDNHLYVLHLFGEYLFVAINGDHSESEGDLRRKLCVLKYLFEVHFGLVTVDGQLIRKELRPPDLEERARVWKHFQRLLGTYSYLRDREQSFAVEAVERLIHPQLCEQSIETLERHVVQAINASPERGGEEVLHAFLLVHCKLLAFYSGHGASTLRPADLLALILLVQDLQPSPGTTEEEEEEEDSDSPQRRPKSSQNIPVQQARSQSTSVPTRSSRETDTDSISLPEEYFTPAPSPGDQSSGSLVWLDGGTPPSDALQMAEDTPEGLASHSPELPSPRRIFLDANIKENYCPLVPHTMYCLPLWPGINMVLLTKSPSTPLALILYQLLDGFSLLEKKLKEGQEAGSALRSQPFVADLRQKMDKFIKNRVGQEIQNTWLEFKSKAFSRSEPGSSWELLQVCGKLKRQLCVIYRLSFLVTAPSRGGPHLPQHLQDRAQKLMKERLLDWKDFLLVKSRRNVTMVSYLEDFPGLVHFIYVDRTTGQMVAPSLSPNEKMSSELGKGPLAAFVKAKVWALVRLARRYLQKGCTTLLFQEGDFRCSYFLWFENDMGYKLQMIEVPVLSDDSVPIGVLGGDYYRKLLRYYSKSHPSEPVRCYELLTLHLSVIPTDLLVQQASQLARRLGEASRVTLP
What is the function of this protein?
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form.  The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.
What are the official names of this protein?
BLOC-3 complex member HPS1, Hermansky-Pudlak syndrome 1 protein homolog.
Protein: IHFB_VIBPA
Sequence: MTKSELIERLCAEQTHLSAKEVEDAVKDILEHMASTLESGDRIEIRGFGSFSLHYREPRVGRNPKTGDKVELEGKYVPHFKPGKELRERVNLG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL4_STRPG
Sequence: MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGNEFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: YIJ1_SCHPO
Sequence: MAKRVVSPNPMLSLETENIAKMGTLTADSLGSMWNVFTKCAENLENGRRLENISWRLWYREAMMSDANDACQIACQESSVPDLSSSCDSINSTVESDAGHVVDSNSFNRIDNVSVNAPIVNEVSLQAPMKGGSHSSIVRPQAKRSSSRLLSTDAFSQFISSFSPPEKPSMKDLALFHGNKSPSSKETIPKVSNSNSSDTSTDDQAYLNVSVSENEHADRSIKTHSSAPPLNQQKSSTSVNDAVSKAIQLVKSTSDLGSLSTNTSSTAQKNKSRKPTKSFSDAVAAASRAKELEKEKLSKVTVTPDDSTSIIRGFDPRLPVLSTKNVSHEEKSHSVQDDKSKQLLKPNPTQPYFYLRGSFDTGHSASSSICSAAVDSESVNSADFPHRTVYDPLPTHAIAESISQENVIEDDDDDDDAWVSVDEAESPHFTKRSPAPYLSKSFRNSALSLLLSQDEKLQHDVRSASSAALNLPRDTDIKATPNLSQSGNINSDNSDLSNYPYNDYRVYRMSHCSSNSNKVLASEISESLRRDLLWERRQKAAMNSAVLRRQSSQSSGANDDKEVRNRKVVEKGFANDCSVW
What are the official names of this protein?
Uncharacterized protein C1420.01c.
Protein: NAGS_YEAST
Sequence: MWRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLHKVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNIPHIDKFFILNNAGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLTKREPRSQNLLHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNPLVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNAAPSNSDAVLVTTVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSPKLDINKFKSIIDQSFKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLGISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLFYYGNPQYAKRALRDKKRLREFMRSVRDIKPSWENEKNIS
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HACD1_MOUSE
Sequence: MGKGDWRQGRVEMPCAHVSRLHKTCVQVRVRVTMASSEEDGTNGASEASDEKEAAGKRRRLGLLATAWLTFYNIAMTAGWLVLAIAMVRFYMEKGTHRGLYKSIQKTLKFFQTFALLEVVHCLIGIVPTSVLVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVSWTVTEITRYSFYTFSLLDHLPHFIKWARYNLFIILYPVGVAGELLTIYAALPYVKKSGMFSVRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIAEKDD
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Protein-tyrosine phosphatase-like member A.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MZB1_HUMAN
Sequence: MRLSLPLLLLLLGAWAIPGGLGDRAPLTATAPQLDDEEMYSAHMPAHLRCDACRAVAYQMWQNLAKAETKLHTSNSGGRRELSELVYTDVLDRSCSRNWQDYGVREVDQVKRLTGPGLSEGPEPSISVMVTGGPWPTRLSRTCLHYLGEFGEDQIYEAHQQGRGALEALLCGGPQGACSEKVSATREEL
What is the function of this protein?
Acts as a hormone-regulated adipokine/pro-inflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes.  May have a role in the onset of insulin resistance.
What are the official names of this protein?
Marginal zone B- and B1-cell-specific protein, Mesenteric estrogen-dependent adipose 7, MEDA-7, Plasma cell-induced resident endoplasmic reticulum protein, Plasma cell-induced resident ER protein, pERp1, Proapoptotic caspase adapter protein.
What is the protein family that this protein belongs to?
Belongs to the MZB1 family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum lumen. Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
Protein: CD52_MACFA
Sequence: MKRFLFLLLTISLLVMVQIQTGVTSQNATSQSSPSASSNLSGGGFLFFVANAIIHLFYFS
What is the function of this protein?
May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
What are the official names of this protein?
CAMPATH-1 antigen, Cambridge pathology 1 antigen.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: AROA_JANMA
Sequence: MKHYPHYLDLKPAMHAKGVVRLPGSKSISNRTLLLAALAQGTTHIRDLLASDDTHVMLMALQKLGVKWEQIGESQDYIVHGVDGSFPVHQADLFMGNAGTAIRPLTAALAVTGGDYTLHGVSRMHERPIGDLVDALNAIGTHIEYTGEPGYPPLHIQRGRIHAHEMSVRGNVSSQFLTALLMAAPLMTREQDVIINVIGDLISKPYIEITLNLIQRFGVEVQRNGWQSFTIKAGQRYISPGNIHVEGDASSASYFLAAGAIAGGPVRVEGVGRDSIQGDVRFVEALEQMGATVRMGDNWIEAESNGVLRAIDADFNHIPDAAMTIAVAALYADGPSILRNIGSWRVKETDRISAMATELRKLGAIVEEGEDYLKVTPPAEILSAAIDTYDDHRMAMCFSLATLDGAARRGNKERINDPQCVAKTFPEYFEAFAKVTEESLF
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBSAG_HBVA5
Sequence: MGGWSSKPRKGMGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPIKDHWPQANQVGVGAFGPGFTPPHGGVLGWSPQAQGILATVPAMPPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTAFHQALQDPRVRGLYFPAGGSSSGTLNPVPTIASHISSISSRIGDPAPNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGAPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSTTTSTGPCKTCTTPAQGNSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYNILSPFIPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: SEC11_LODEL
Sequence: MNIRQQLTQLLTLGYVFASAFMLWKTLSVVANLHSPIVVVLSGSMEPAFQRGDILFLWNRDEKQKVGDIVVYEIEGKTIPIVHRVLREHHNLEKQLLLTKGDNNAVDDLSLYAKKQSYLNRKNDLVGTVKGYLPFIGYVTILISENQYFKFGLLGLLGLSSLFSNE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: KHSE_CORJK
Sequence: MGVEIPVGRKATVKVPASTANLGPGFDTLGLALGLYDYVTAEVIESGLEVEVTGEGEGEVPLDERHLVVRALRATLKEADVTVPGLRVSCTNSIPQSRGLGSSAAAATAGVAAGNGLAGFTLDDQAQVQIASTFEGHPDNAGASVLGAGVVSWTNTPIDGVSAPAYHARRIDVHPDIKATAFIPDFHASTEAIRRVLPSDISHVDARFNVSRTAVMTVALRDDPDLLWEGTRDRMHQTYRAEVLPVTAEWVNRLRNLGYPAFLSGAGPTILVLSTEPVDNALVEEARGRGMKVLELGIAGPVEVDVTG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_HAEIE
Sequence: MFRGATAVNLDSKGRVAIPTRYRAEILEKNQGQMVCTVDIRQSCLLLYPLDEWEKIEQKLLALSNFDPTQRRLQRVMLGHATECEMDAQGRILLSGPLRQHAKLEKGLMLVGQLNKFEIWSDVEWHTQIAEDIEIGSSTDFAADALNDFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NALP2_HUMAN
Sequence: MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHKFKYAFYLSCRELSRLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIEDICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYTLEKEEEEDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKGGHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEKSSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI
What is the function of this protein?
Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF.  When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B.  May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y010_HALH5
Sequence: MTEKRFAGTRIEVNGIVVAKITSFTHSLEVEEADVTGLGDVDEGSSVFRQKFIASAIGETAAMEGVVLVDDAGQSELKRVAESGQDAVVKHTDENGNGYELTGFFTTYEEEGSVSEGVYTFSGEFRVNEKSVVSGDESA
What are the official names of this protein?
Uncharacterized protein BH0010.
Protein: MSCL_LISMC
Sequence: MKKMLVEFRDFALKGNVLDLAVAVVIGAAFGKIVSSLVDNIIMPLVGVLLGGLDFTDLSFKVGKSVIQYGAFIQSIVDFVIIAFAIFIFVKVLTSFIKKKEQTVEETPVPPTEEYLKEIRDLLKEQQK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LSRB_SALTY
Sequence: MARHSIKMIALLTAFGLASAAMTVQAAERIAFIPKLVGVGFFTSGGNGAQEAGKALGIDVTYDGPTEPSVSGQVQLVNNFVNQGYDAIIVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSYYINQGTPKQLGSMLVEMAAHQVDKEKAKVAFFYSSPTVTDQNQWVKEAKAKISQEHPGWEIVTTQFGYNDATKSLQTAEGIIKAYPDLDAIIAPDANALPAAAQAAENLKRNNLAIVGFSTPNVMRPYVQRGTVKEFGLWDVVQQGKISVYVANALLKNMPMNVGDSLDIPGIGKVTVSPNSEQGYHYEAKGNGIVLLPERVIFNKDNIDKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MURB_CHLT2
Sequence: MTDSFPFSVQESVPLSRFSTFRIGGPARYFKELTSLSEALTVFSYLHTHPLPYIIIGKGSNCLFDDQGFDGLVLYNNIQGQEFLSDTQIKVLSGSSFALLGKRLSSQGFSGLEFAVGIPGTVGGAVFMNAGTTLANTASSLINVEIIDHSGILLSIPREKLLFSYRTSPFQKKPAFIASATFQLTKDPQAAKRAKALIEERILKQPYEYPSAGCIFRNPEGLSAGALIDRAGLKGLKIGGGQISEKHGNFIINTGNACTADILELIEIIQKTLKKQGISLHKEVRIIPFRL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_COREF
Sequence: MNHDSILLGLIGEDISLSRTPAMHEAEGLAQGAATVYRRIDTLTDRARGRSLQELLDAARSTGFNGLNITHPYKQAVLPLLDEVSEQAAQLGAVNTVVIGEDGRTSGHNTDVTGFARGLEEGLPDATMTTVVQVGAGGVGNAVAYSLVTHGVEQLQVADLDPARAQALADAINSAIGREAVHGIDARGVEEAIAAADGVVNATPMGMLAHPGTAFDTSCLTPHHWVGDVVYMPIETQLLKDARALGCRTLDGTRMAIHQAVDAFRLFTGLEPDVERMRATFLSL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids, and plays a key role in the quinate degradation pathway.  Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively.  It can only use NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase (NAD(+)), QSDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NDHI_PROM5
Sequence: MKDFLQKVNSYIKEAFGAGKYLYDGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEVSSSDARVGKLPEEVYDWMKPKTNEMSDPAVKLNK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ATPD_SOLUE
Sequence: MTLSAVATRYANALADVVSPGSSPIRPEAALEELRAFEAALKSSVELHNALTSPSVPVGRKRAVVGRISDTLKISPIVRNFLFVLVDHRRIASLTEILHSFELIMDERLGFARAEISSARELTEPQRTALSAQLAQLTGKQIRMRFAVDEALIGGAVARIGSTVYDGSVRGQLQTLERRLSTER
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DDL_OCEIH
Sequence: MKKKVGIVFGGKSAEHEVSLQSAKNIVDAIDSDKYDVYLLGIDKQGNWHVNDRSHYLINEEDPKLISLNKTNEGIAVIPGAEKNQIVTSNSTKSLDQLDVIFPIVHGTLGEDGSLQGMLRMANIPFVGSSVLGSAISMDKDIAKRLLKDAGLKVAKGYAYRSVDKESIHFDSLKEELGLPMFIKPANQGSSVGVHKVENEEQFYSAIKDAFQFDHKLLVEEAIVGREIECAVLGNEKPAASVPGEILPTGDFYSYEAKYIDETGAVLQIPAKLEEPVVDSIQDIALQAFKALNCEGLARVDVFLTDDNEIVINEINTLPGFTKISMYPKLWEESGVSYRELIENLIELAIERNQRDQQLKSSRSDG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_PSE14
Sequence: MAQKTIRVGSIEIANDKPMVLFGGMNVLESRDMAMQVCEEYVRVTEKLGIPYVFKASFDKANRSSVNSYRGPGLEEGMRIFEEIKRTFNVPLITDVHEPHQAAVVAEVCDIIQLPAFLSRQTDLVVAMAKTGAVINIKKAQFLAPQEMKHILTKCEEAGNDQLILCERGSSFGYNNLVVDMLGFGVMKQFEYPILFDVTHALQMPGGRSDSAGGRRAQVLDLAKAGISQNLAGLFLEAHPDPDNAKCDGPCALRLDKLEPFLAQLKSLDELVKSFPIVETA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_YEAS8
Sequence: MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMATEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEGKEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDSISDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: CU67A_LOCMI
Sequence: GYLGGYAAPALAYGAAPAVAYAAPAAYAPAALTSQSSNILRSYGNLGQVSTYTKTVDTPYSSVTKSDVRVSNDAIAHVAAPALAYAAPAAYAAPAYYH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 67, isoform A, LM-ACP 67A, LM-67A.