PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_LEGPH
Sequence: MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVHSTKDMPAQLPDGLLLTAICKRDNPFDALISPQFKSLAALPKNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELVHGLNDPISALCVHTERRVNAKLGGNCHIPFAVYCTITEEKLLLLRAKVLNMDGSQMIDDEQQGKIAEAEVIADRCTESLMTKGAMSLLSTIPS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MUTH_PHOLL
Sequence: MNTLFSPPSPPDNEQQLFECAQLLAGLSMGELAAKANLPIPPNLKRDKGWVGMLLEYYLGASAGSKPEQDFEHIGIELKTIPVDRRGYPLETTFVCVAPLTGNSGITWGSCHVRRKLSRVLWIPVEGEREIPLAKRRVGSPLLWSPNQEEEELLRRDWEELMDFIVLGKVESVTARHGEVLQLRPKAANSKALTEAIGVHGQPIMTLPRGFYLRKNFTAPLLARHFLI
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_HELPG
Sequence: MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRERIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNALLED
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3997_METAC
Sequence: MQITSNEISVEVNGQSYTLPAGSTLGDALEVSRASYIAGTAVGIIKRAAEKRTEEITEYAIKTPRGELRIELKDPESSSGKLWAEHYKEYEGTYIHWASPEALAFGPFEADIKPFHETGSFEAFDVVFGAGGFDPHNTHLIISRKRHVAEYGAPEDGVFATVVTGRNLIFRLSREDPILSIEPIIEWEQLAEKTCTTDLSTILEDEDSVFTYFEVELSRNSPKGAEHFYALTRKGTLSVDVTTSSFISDDTLREEPVPYENFELRKEGAISVRTVGYGTGRTYISREERPSSLVHSIVGQVITGIELIKLAEKGQKLSVESLPPQIVLLGHSFEEVEPVLTAIGIELVKEGYTEENAVIVKQDPPTTLEILGEAKVTAYGVPREKLIEVELYPERAPKSVDFFRHSLELKTKPVGKLPVHMIYDNTYLFKTEKEAVKYKEVLPENTPADTVLAGEIGITNQAAKRMGTIGVRLVDDDLFGPTGEKFSSTNIIGRILEPERLIGIEEGDAIYVSEVVRRKTDEQEN
What are the official names of this protein?
UPF0288 protein MA_3997.
What is the protein family that this protein belongs to?
Belongs to the UPF0288 family.
Protein: EMC4_MOUSE
Sequence: MTTQGGLVANRGRRFKWAIELSGPGGGSRGRSDRGSGQGDSLYPVGYLDKQVPDTSVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESSSQKFLQGLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEPPERMEFSGGGLLL
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 4, Transmembrane protein 85.
What is the protein family that this protein belongs to?
Belongs to the EMC4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Could also be a single-pass transmembrane protein with cytosolic N-terminus and lumenal C-terminus.
Protein: TRMD_STRS2
Sequence: MRIDILTLFPEMFAPLEHSIVGKARDKGLLEINYHNFRENAEKARHVDDEPYGGGQGMLLLAQPIFDTMDSIEQTKPRVILLDPAGRTFNQAYAEELAQEEQLIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKEVSHTDDSFSSGLLEYPQYTRPYEYRGMVVPDVLMSGHHENIRKWRLEESLRKTYQRRPDLLENYNFTAEELTIFEKIKAEDTVD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_NITWN
Sequence: MPTAVTGPEIERLIQLLARLPGLGPRSARRAALHLIKKREALMAPLASALQVAIDRIRVCETCGNIDTRSPCTICTDARRDPSIIVVVADVADLWALERAGATNGFYHVLGATLSPLDGVGPQDLTIDALVARAHDPRVAEIVLALNATVDGQTTAHYITDLLGEANVKVTRLAHGVPVGGELDYLDEGTLSAAMRQRTLF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ERA_BORPE
Sequence: MSNPQFRAGFVAIVGRPNVGKSTLTNALIGTKISIVSRKAQTTRHRIHGVLTREHEQFVFVDTPGFQTRHGGAMNRMMNRVVTQALADVDVVVHVVEAGKWSEGDAKLLPLLPKSRRSILVVSKIDALKNRDELFPFVSKLMALHAYDAVVPVSATKGQQLDQLLDEIAAGLPQGDPMFEEDTLTDRPVRFIAAELVREKIFRLVGDELPYGCTVVIEQWEETERGVRIAACVVVERESHRPILLGAGGMHMKRIATEARQDIAKLLDMPVHLEIYIKVRKGWSDREGALRDLGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: MIAB_XANCB
Sequence: MPGTSVSDLPTTATAVDAPALLPLPVGRPQAPALVRGKLYIKTHGCQMNEYDSAKMADVLAASEGLELTDNPEDADVVLVNTCSIREKAQEKVFSQLGRWKALKAGGKPVIIGVGGCVASQEGEAIVKRAPYVDLVFGPQTLHRLPELIRARRESGKSQVDISFPEIEKFDRLPEPRADGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGAYGADAGEPAQYADLGLLIRTIAQIDGIGRIRFTTSHPLEFSDSLVDAYRDVPQLANYLHLPVQAGSDRILSAMKRGYTALEFKSKIRKLRAVRPDISISSDFIVGFPGETDADFDKTMKLIEDVGFDQSFSFIYSRRPGTPASDLEDDTPDAVKQARLARLQAHINAHAAGISQRMVGSVQRVLVEGPSRRDANELTGKTENMRPVNFPGNPRLVGQFVDVLITEALSNSLRGRIQLDDSAA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_CERS1
Sequence: MTTVTRFAPSPTGYIHVGNLRTALMNWAIARKSGGTFILRLDDTDRERSKQEYSDGIMEDLEWLGLTWDRLERQSDRLDRYAEAADELRRAGRFYECFESPTELDLKRKKLLNMGKPPVYDRAALKLSDEERARLRAERGGYWRFLLDQERIEWTDGILGPISIDAASVSDPVLIRADGQVLYTFASSVDDIDMGVTFIVRGGDHVTNTATQIQIMQALGGTPPSFAHHSLLTGAQGEALSKRLGTLSLRDLRARGVEPMALLSLMARLGSSQPVELFRTHEELLAGFDVSTFGAAPTKFDAEDLFPLTRHYVQGLPFEAVRGRIAALGVPDDLAEPFWRVAKDNIGVLEDLGGWWTLFSEGAEPQIDPEDEDFIRQAMTLLPPPPYGPESWAQFTAAVKEATGRKGKGLFMPLRKALTGQAHGPDMSEVMPLLQKVRAKG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SALDC
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLSVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLALDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3PASE_ACET2
Sequence: MGKEIEKKFIVSGDAYKSLAKGVLYRQGYIFFDKDKSVRVRVFNDKGYLTVKGTSTGISRLEYEYEIPVGEANEILEYLCEKPVIEKLRYKFQFEGFTWEVDEFLGENEGLVIAEIELPDENAVFKKPDWIGREVTGDPRYLNSNLVKNPYKNFKE
What is the function of this protein?
Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked).  Catalyzes vigorously the hydrolysis of inorganic triphosphate (PPPi), however it can also catalyze the hydrolysis of ATP to ADP and phosphate.  It can use ribonucleotides such as GTP, CTP, or UTP and deoxynucleotides such as dATP, dGTP, dCTP, and dTTP.
What are the official names of this protein?
Inorganic triphosphatase, PPPase, Adenosinetriphosphatase, ATPase, Polyphosphatase.
Protein: UPP_BRUMB
Sequence: MGVTVVSHPLVQHKLTIMRKKETSTASFRRLLKEISLLLCYEVTRNLELTTMSIETPLMPMEAPVLEGKKLVFASILRAGNGLLEGMLDLVPAARVAHIGLYRDHDTLQPIEYYFKAPEDIVNRLVIVVDPMLATANSAIAAIDKLKERGATNIRFLCLLAAPEGIERFTKAHPDVEVFTASIDECLDEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS15_ONYPE
Sequence: MALTKEQKQEIIKQNSRFAKDTGSSEVQIAILSAEIKQLSEHLKQHPHDFHSKRGLFMKNSKRRDLVKYLANQN
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GATC_STAAN
Sequence: MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: SNG2_MOUSE
Sequence: MESGAYGAANAGGSFDLRRFLSQPQVVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQDVRVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGVDAFIQNYVDPTPDPNTAYASYPSASVENYQQPPFTQNVETTEGYQPPPVY
What is the function of this protein?
May play a role in regulated exocytosis.  In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles.  May also play a role in GLUT4 storage and transport to the plasma membrane.
What are the official names of this protein?
Synaptogyrin-2, Cellugyrin.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes.
Protein: APBC_RICPR
Sequence: MANLHQQQIIDKIQNITFKDGTFLNEVISDIIIKGNNIGFSIDISGKNKLEAEEIRLKAINKLNNIKEVNKITIVFTQSKTIDKKAQKPKHFVENVKKIILVASGKGGVGKSTISALIAQQLSLENYRVGIVDADIYGPSIPHIFGINGIPKTVEGRIVPILAQNIQIISIGFFVKAHSAIIYRGPMASKIIYQLLSNTRWNNLDYLIIDMPPGTGDIHLSIIENYHLDGVIVVTTQQKISEIDVIRSIDLYRKLGLPILGIIENMIYMLESDHCGYLSKKYHIPLIAQIPIMPQIANACDKSLPLTNLLTLPLEKYL
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: GRPE_SYNY3
Sequence: MNEDQVSLENQTNPVSPEASDVPAVTPEESPQPTDAVLGEPSGEQSEDPRIGAATETEGGPLEQEKSSEEIIAILQKDLASHRQELAEQSEQLDSIKKRYVALAAEFDNFRKRTQREKEEQAKLIKGRTITELLPVVDNFERARTQIKPNSDGENQIHKSYQGVYKNLVDSLKGLGVAPMRPEGKPFDPKYHEAMLREPTAEYPEDTVIEELVRGYLLDDIVLRHSMVKVAVAPEEGAEVVNGEAGANP
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B1C_MOUSE
Sequence: MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-C/E/G.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ARGO_SALA4
Sequence: MISYYFQGFALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCALSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OBG_STAS1
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGDGASIIFEVDEGLRTLLDFRYQTHFKAKRGDGGQSSNMHGKNAEHLVLKVPPGTIIKSADSEEVLADLVENGQRAVVAKGGRGGRGNSRFASPRNPAPDFSENGEPGEEIEVTLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTKDQRSFVMADLPGLIEGASEGIGLGHQFLKHVERTKVIVHMIDMSGSEGRDPYEDYKVINEELSAYEHRLEERPQIVVANKMDMPNAEDNLALFKEEINDDSVHIIPLSTFKHDHIDELLYAIADKLEAVKDIDFSKDEEEDLGVNRVVYKHTPSQDKFTITRDDDAAYVVSGKAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRARGCRNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_ACIBS
Sequence: MPRRRVVAAREILPDPKFSSQTIAKFMNHVMQDGKKSIAESIVYGALERVQEKNKVDPVEFFETTLEKVRPMVEVKARRVGGATYQVPMEVRPSRRTALAMRWLVDAAAKRSEKTMALRLAGELLDAAEGKGAAIKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GLMU_PROM0
Sequence: MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCVELKPDQIFVITGHKSKEVEKSISNEKKIHIVIQEPQSGTGHAIQILCREVKKHEGKLLVLNGDVPLIRPSTLKRLLYLHDSKNADVSLITTKKRNPHGYGRVFLKGDFIERIVEEKDCNDLERENRLINAGVYCFNWGKLSEIINTLRSNNNQKEIYLTDTISMLKNSLSLEVEDNGELQGINNRIQLSECEENMQNSIKEKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHLRGNTKIKSHCIIGPNTFIENSYVGLNCEISNSTVYASQIMDYIKIGPYSHIRPNSKISSFSKIGNFVEIKNSQLEEESKVNHLSYIGDSIIGRSTNIGAGTITANFDGEKKHQTKIGKNSSIGANTVFVAPINLGESVTTGAGSVITKDSKDNSLAISRTQQVNIENWERKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CITK8
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARVKVRITEYEKDANGEFVAKTSLKDTTIGRAILWMIVPKGLPFSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQTMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEQQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGILMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIRLSNAKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGSVMAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTTGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARVPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVITPVDGSEPYEEMIPKWRQLNVFEGERVERGDVVSDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIENAGSSDFLEGEQVEYSRVKIANRDLEANGKVGATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGELPAAPQVTAEDASASLAELLNAGLGGSDND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UGT_FRAAN
Sequence: MGSVGSDNTHIFLVCYPAQGHINPMLRLGKYLAAKGLLVTFSTTEDYGNKMRNANGIVDNHPTPVGNGFIRFEFFDDSLPDPDDPRRTNLEFYVPLLEKVGKELVTGMIKKHGEEGGARVSCLVNNPFIPWVCDVATELGIPCATLWIQSCAVFSAYFHYNAETVKFPTEAEPELDVQLPSTPLLKHDEIPSFLHPFDPYAILGRAILGQFKKLSKSSYILMDTIQELEPEIVEEMSKVCLVKPVGPLFKIPEATNTTIRGDLIKADDCLDWLSSKPPASVVYISFGSIVYLKQEQVDEIAHGLLSSGVSFLWVMRPPRKAAGVDMHVLPEGFLEKVGDNGKLVQWSPQEQVLAHPSLACFLTHCGWNSSVEALTLGVPVVTFPQWGDQVTNAKYLVDVFGVGLRLCRGVAENRLVLRDEVEKCLLEATVGEKAVQLKHNALKWKKVAEEAVAEGGSSQRNLHDFIDEIARTSIA
What are the official names of this protein?
Putative UDP-glucose glucosyltransferase, FaGT5, Glucosyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RL1_CERS4
Sequence: MAKVGKRTRSAREAFVGKDLISVEDAVALIKQAASAKFDETLEVAMNLGVDPRHADQMVRGVVTLPNGTGKTVRVAVFARGAKADEAKAAGADIVGAEDLMETIQSGKIEFDRCIATPDMMPLVGRLGKILGPRNLMPNPKVGTVTMDVKSAVEAAKGGEVQFKVEKAGVIHAGVGKMSFEADKLAQNVRAFVDAVNRAKPAGAKGTYLKKVSLSSTMGPGVSVDLTSATSH
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LEUC_ECOLC
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAIAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.