PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_THEFY
Sequence: MSIDVANESGVPADEERLARLARYILDALRVHPLAELSVLLVDEEPMADLHVRWMNEPGPTDVLSFPMDELRPGAPGRTSEPGILGDVVICPQVAARQAERAGHSMQDEIDLLCTHGILHLLGYDHAEPDEHREMFSLQNELLAGWRRSLEEEER
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_BORAP
Sequence: MDNDEIFSKVRSIISEQLDKKEDEITIDSRFVEDLNADSLDIYELLYLLEEAFDDKIPENEANEFETVGDVVNFIKKRKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC45_HUMAN
Sequence: MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIKQDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEARRRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS
What is the function of this protein?
Required for initiation of chromosomal DNA replication.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
Cell division control protein 45 homolog, PORC-PI-1.
What is the protein family that this protein belongs to?
Belongs to the CDC45 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MRAY_AGRVS
Sequence: MLIWLVELANHVQFFNLFRYITFRTGAAMFTAALIVFLFGPKIIASLKVRQGKGQPIRADGPQTHFKKSGTPTMGGLMILAGIVGSSLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLAIEFLIAGIAVFFMMEAAKISAPQGPHLATSIAFPFFKDALLNVGYFFIVFGGFVIVSAGNAVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFSGYLQINFVPGTGELAVILGSVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIGGLFVMETLSVIIQVFWYKRTKKRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_AQUAE
Sequence: MWERERKKFLEDIRKKSLQELEKLLDELKLELTRLRFKKQVQGLENPMEMRKVKRNIARVLTVIREKQLRGEG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: FTSA_ECOL6
Sequence: MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKRVTASVGSWIKRLNSWLRKEF
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: GFOD2_XENTR
Sequence: MKTLPGIGVFGTGNTARVLISLLRADGFSIEALWGKTDEEAKELAEEMGIPFYTCHTDDVLLHQEVDLVCISIPPPLTRQIAVKALGIGKNVICEKAASSIDAFTMVKAARYYPKLMSLVGNALRFLPAFDRMRQLILEQNYVGEIRICDVRVYGGSLLSSNYSWICDDLMGGGGLHTLGTYLVDLLTHLTNKRAEKVHGFLKTFVKQNEAISGIRYVTSDDFCFFQMQMTGGACSTVTLNFNMPGTFVHEVMVVGSAGRLVVRGTELFGQKNSASEEKLLLSDPLTREIADISDFEKVPPPYLMGIAHMVKALRQSFQDQEDRRTWDQKPLSVAATFEDGLYMQRVVDAIKRSNRSGEWESVELTNDETDSNQNLSEVIQHNL
What is the function of this protein?
Promotes matrix assembly.
What are the official names of this protein?
Glucose-fructose oxidoreductase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CARFA_XENLA
Sequence: MADDVSEFLGQNPETAAWLELVHGECESDKLWRYRKEFILRNLSDVCGEAEVPPPPETNHKALDRLLAYSMVWANHVFTGCRYPLPVMEKVLKMAENIKVTDAPTHTTRDELVAKVKKRGISSSNEGVEEEPCKKQKSSDHGERESSYIEDTISDGNVPSTSLNKREARLSAAQRTDVNTEFYDKSSNRRSLPVSNAKSRLNLPEEAGYKHGATQGRKSHSDIRHQTSMKGPAQSSDNALKPTRRFTTEHTKERQPFFNRLYKTVAWKLVSAGGFNANLNHEELLNTCIESLKATLEVSFVPLTDLADLPQNKTSQENTVCELRCKSVYLGMGCGKTMETAKAVASREAVKLFLKKKVVVRICKRKFNGRDVEDLVLVDEEFRPVNLPPAIKNPQEIV
What is the function of this protein?
May regulate DNA damage response and cell proliferation.
What are the official names of this protein?
Protein CDKN2AIP homolog A.
What is the protein family that this protein belongs to?
Belongs to the CARF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: YCF3_SYNS3
Sequence: MPRSNRNDNFIDKSFTVMADLIVKLLPINARAKEAYVYYRDGLSAQNDGDYAEALENYEESLKLEENAIDRGETLKNIAIIYMSNGEEERALETYQKALDENPKQPSCLKNMGLIYEKRGRTAEEEGRRDDADGWFDQAANVWTQAVRLNPGGYLDIENWLKSTGRSNVDVYF
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RL36_THERP
Sequence: MKVSASVKRRCAKCRIIRRHGIVRVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: AMN1_CANAL
Sequence: MNFHSTKPLSYDSSDNEIYNPFLVSTNEEGRVSPTIDKQQQPVLKRAKSIVSSNSLSAFFTDSKSKQQQQQQQRDRKRNKDRRNRPGRLRRSHSTNSNDQFIMNTGSFKLPDQDEFQFTMNNNSDNGFSSSTSSSDLESVPDLTDDNIDELTPETTPIKPVGNFYFNTLFDNEENTDGYYYKLNSQIKIRNELQQQQQQQQQQRLTSSSPSIFEIPEIVYKIISYVDEQNTILPQESTPIRRNPLSYKHALLIHGDKKSAQSALQKTTNQQSQQNQQPSSVISSSPLYNCLLVNKLFYKITSEIISTKFYSHNEQQLKKFIENKSHQQQNSSSPIIIQPKTFILHKLFQTKQIIFDQLIEFINFDQLSWFELYMCPKISLDKPQSQTFMKIFQSCSNNLTKLIITGSKTIDDEFLMKLGQFKCGDNLQILDLRACELITDFGIYQLSLYCRNLTFINFGRKPISNGNGNGGGNGGSGRYITDNSMIKLINNNRKLSTIGLAGCHITDKCVWEIANKLPNISRLSLNNCPKLTNSGINQIFTLTNTPNSNYFKCLSVLELRFNHQLTDLTSIIKFKRRQKFQFNIILLLELCESLMLKYRQQEFELDKLISLKIFQDISHWVNDYNDNDGDLSYNEIKHLINNNNNNNSSNNISTRGF
What is the function of this protein?
Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints.  Required for daughter cell separation and chromosome stability.  Involved in copper sensitivity.
What are the official names of this protein?
Antagonist of mitotic exit network protein 1.
What is the protein family that this protein belongs to?
Belongs to the AMN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLS1_BACSU
Sequence: MLKRRLEFFFLYMMLIGAYVIWFFPVSRLEFYGGLLCYISIILFSIYSLILENRTSQHTLLWIHILVFFPIVGYVFYLFSGQLYVKGKLFKTKRMYNREKLRKLFDKEETPEVTGLKDNQERFFTYSIRAAHMNINTKSNIKVLKNGEETFPDIFKAMRKAESYIHIEYYMFKSDMLGRGMMDIMMEKARQGVEVRFLYDAAGSMKLARRDIMRMKQAGVDIVPFSPLKYGFFNQKLNFRNHRKIVIIDGKTGFVGGLNVGKEYISRDPYIGFWRDTHLRLEGEIVQTLHAIFMLDWEYVSNEVLIDQEEYNTPVPVEGGGIYQIVATGPDMKESMSDLYYEMISSAQKSIWIATPYFVPNESIRTALKAAATKGVEVRVMVPEKNDSFLTQYASRSYFPELLLEGIEVYSYQKGFMHQKVMIIDGDLASVGTANMDMRSFQLNFEVNVFFTDAEAIRTLEAHFEEDMQESEKLSPVGFYKRGVADRTKESFARLFSGVL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity).  May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock.
What are the official names of this protein?
Probable cardiolipin synthase YwiE, CL synthase 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIC_LEPBL
Sequence: MESTQEFQVPLKTIRLTDGTEYQSYHTEGSLSDKKPSDYKNGIPKIRKEWIRTRLDRGDTNHSQMYYAKKGIITEEMRYVALRENMNPEFVRLEIACGRAILPSNRNHPELEPMIIGRNFLVKINANIGNSALGSSIEEEVEKLHWAVKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKAGNLNIQVFLDTLEERAEQGVDYFTIHAGVLLRYIPFTANRVTGIVSRGGSILAKWCLAHHKENFLYTHFDEIIKVMKKYGVSFSLGDGLRPGSIADANDKAQFGELETLGELTKRAWEEDIQVMIEGPGHVPMHLIKENVDLQMKLCQEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWFGMAMLCYVTPKEHLGLPDKEDVKQGVIAYKIAAHAADLAKGHPGAIKRDNLLSKARFEFRWEDQFALSLDPETAKSFHDETLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKGMEEKSEVTICNRKKESGK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y1364_STAAR
Sequence: MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSPAFTVEPKEDVDIGYEQQYDDLNVVIAEKDLWYFEDDHIIVNVVDHEDEISYSKK
What are the official names of this protein?
Uncharacterized protein SAR1364.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PROQ_SALNS
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVERVGGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNSCGELEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPVARRKEGAERKPRADKPTTKAPRAPREEKHTPVSDISVLTVGQSLKVKAGNNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_STRR6
Sequence: MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARINLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTGMTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TCTP_DANRE
Sequence: MIIYKDIITGDEMFSDIYKIKESENGMMLEVEGKMITRAEGDIDDALIGGNASAEVADEGCDSTSVSGVDIVLNHKLQETSYDKKSYTAYIKDYMKAVKAKLQESAPNRVDPFMANAPAEVKKILGNIKNFQFFTGESMNPDGMIGLLDFREDGVTPYMIFFKDGLEIEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMT8_CANAL
Sequence: MKFPKLRKRTVYWAVLTVFALFTIHFVFQYKEHNSHRVQPIVLIPKAFPSLILNSFDTQNEELVPIKLLKNCQIIRSYHTGYEENTKLLGQEPQSNFHKFNFTVFSSMKPIGLDLKQCQLLSSSSQVEVNDAVNMDASLHDILGKLLQDIRHGKLEYLQEIAPFFLPELQLQLNLNIVDRFWYRFSGSSIWLDQYNMYFMISRIAYSPHGVKNQPVVSLTYGQLFDRNWNEVKNINLLVPSNDPSKNGGHDSFRIISFPYFLPIPFWHDIDNTDGNYFGPEDPRLILVRNKQGYEEPLLIFNSYHRKFVHYDDDEDSIMGQTVKFQRSMFMCWPWQYQMGKSNVEGTSNPEYDNKVYNRVIELKVKLLADMKSQKNWTPFISEDSTNKFDSYIYFVYRWANLDVLKCSLLGDVAGDCVFDYRLDETLVPQNKVGPLRGGTQLVNLRQVIPRSVYHRLLPSHREIFIGFARTHLDNCGCGKVMYRPNLVILVKDAADKTYYKISHISSSLSFDVPIIGWNVYKPDDLCFDSNVLIPYSVSNWNITSLELDIEGGRWVSNDQLTLTLSISDSTVHRLDIRGLFQSILDLADRSLFIPVDRETRVIDEFQNGLQNPGSNPLNQDVNSLGVNNDNIVCALDASVEFCFEYGAKFSIPKQEEFYEVEQQEFNEELIDPKKHQYFKILGKYLYDHASVNS
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis through beta-1,2-mannosylation of cell wall phosphopeptidomannan (By similarity).  Plays a role in the ability to produce hyphae in the presence of three bacterial species.
What are the official names of this protein?
Beta-mannosyltransferase 8, WRY family protein 3.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: CCD42_HUMAN
Sequence: MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEFEEIHEVIARYKTLVSMRHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQQNNELARLQMRFDRARSNVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVRI
What is the function of this protein?
Required for sperm development.
What are the official names of this protein?
Coiled-coil domain-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the CFAP73 family.
Protein: PRIS_SULIK
Sequence: MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPGARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGGENAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: ISD11_YEAST
Sequence: MPGFTAPTRRQVLSLYKEFIKNANQFNNYNFREYFLSKTRTTFRKNMNQQDPKVLMNLFKEAKNDLGVLKRQSVISQMYTFDRLVVEPLQGRKH
What is the function of this protein?
Required for mitochondrial iron-sulfur proteins biosynthesis.
What are the official names of this protein?
Protein ISD11, Iron-sulfur protein biogenesis, desulfurase-interacting protein 11.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CT151_CONPE
Sequence: MRCLPVFVILLLLIASTPSVDALQKTKDDMPLASFHDNVKRILQTLSNKRSCCPTILSCCFV
What are the official names of this protein?
Conotoxin Pn-B0151.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTRC_METAC
Sequence: MSAGGAGGEAKGGFPPQTIMAIGAIGGLAGIYLGNFMPAQFSFFGGLGAICAMVWGADAVRRVASYGLGTGVPSIGMISLGMGIVAALFGLSVGGIAGPIVSFIAAAIIGAVIGVLANKVIGMGIPIMEQAMVEIAGAGTLVIIGLSVVIAGTFDYAEVVEYVVANGYIALIFIIGGMGILHPFNANLGPDEKQDRTLSVAVEKAAIALIITGFASSLHEGLMAAGLNIAVGVIIWAWAFMKYYGYVKRDSYAVVGTGLLPSAEELE
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit C, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C.
What is the protein family that this protein belongs to?
Belongs to the MtrC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIC8_DROPS
Sequence: MDAEHLKRLEGREAEHIPDILNEFNKKHADLLVFDSFHSDNQWHELWLAIFGILDDAQLGHLHTQCLNTVRILTRDEFSLQTNYIEHEVSQLLRLARVEASSLKLPATPDELKQQEEGQLQLQEQPSLAQSDIIAEALKCLCNLVYQSADCRRQCLRQHCLDAILKRVASSMRHPCALEYYDMKLLFLLTALEPAARTRLQIDLNGLTYMTKWLDDKLAEPSCSEEQLNIICELLKVMFNVTSAPDKSPNEYEIQSLHLTGVLRELLLRFGKMATDKERSVVTHAINLLTNISSSCLIELTLKCSNAEEQPKKAVEGVAKAKPAKCCALCFEKRNVRCLTVLLNYLRQALAQQEAEASSHELLSPVLTVLVKCSRSDRVMRHYLRQEILPPLRDVSQRPEIGQELRNHLCRFLTLPAMILRDLAAELLFVLCKEDVGRMIKYTGYGNAAGLFAKRGILDCRRVEGADYSSDSEDSDTEEYKKHQQGINPVLGCVEPKSKHNPLDDMTEEQKESEALQLVNLIEQLRQGGIVKPALIDKDGKPQPLEHILQLQEELPQQQLEQKRKT
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors.  Acts by exchanging bound GDP for free GTP.  Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i) alpha protein independently of G-protein coupled receptors.  In addition to its GEF activity, it plays an essential role in cortical subcellular localization of heterotrimeric G proteins, suggesting it acts as a facilitator of G-alpha function through control of its membrane targeting and/or assembling of associated components rather than a GEF (By similarity).
What are the official names of this protein?
Synembryn, Protein Ric-8.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the cell cortex.
Protein: TBA_PICAB
Sequence: CWELYWLEHGIQPDGMMPSDTTVGVGDDAFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGAYRQLFHPEQLISGKEDAANNFARGHYTVGEEIVDLCLDRVRKLADNCTGL
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NHAA_FRATM
Sequence: MCASQKNQELIGGLILFSAALLAIVVNNSPLASYYAMLETINVKLGIENLVIDKNLMHWINDGLMAIYFLYIGLEIKREIIVGTLSKPSNIITPAIAAFAGLAMPSLIYLSINHDIKVINGWAIPSATDIAFTLGILALLGTRVPAKLKLLVITIAIFDDIAAIAIIAIFYTKSLSLLSLSLGTLFILAMIICNRIFKINRSSVYVVLGFFAWFCTIKSGVHATLAGFTTALCIPFRENDKDSPANFMEDSLHPWIIYFILPVFAFANAGISFSGISFSILFEPITLGIIWGLFVGKQLGIFSILAVFKKLKWFKLGESFSNLQLYGISLLCGIGFTMSLFIGVLAFNDTHLLNAIKIGVVVGSVLSGFFGYIVLRFIVTNPS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDRP_GEOKA
Sequence: MNQRLVYVVSDSGGETAELVVKAAASQFHASPIQVKRVPYVEDKTTLAEVVALAKMNRAIIAFTLVVPEMREFLLAEAAREGVVAYDIIGPLIEKMSHLFQLTPRYEPGQVRVLDEDYFKKIEAIEFAVKYDDGRDPRGILRADIVLIGVSRTSKTPLSQYLAHKRLKVANVPIVPEVEPPEQLFRVGPGKCFGLKISPDKLLSIRRERLKSLGLNDQAIYANMDRIKEELAYFDEVVKKIGCDVIDVTNKAVEETASIIMKKLKR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: EFG_LACP7
Sequence: MAGREYPLERTRNIGIMAHIDAGKTTLSERILYYTGVNYKIGDTHEGTATMDWMEQEQERGITITSAATTCHWTLELEHKKAPGALEHRINLIDTPGHVDFTVEVERSLRVLDSAVGVFCAKGGVEPQSETVWRQADKYNVPRMAFVNKMDISGANFFNVVDMIKSRLGKNAVPIQLPIGKEDTFKGVIDLFEMKAYYYLDDKGEQIEIKEIPDDMKDQAEEYRAAMIESICETDDDLIEAFLEGNEPSNEELKKALRNATISVQIIPVLCGSAYRNKGVQKLLDAVIEFMPAPTDIEDIKGFDEEGNEIHRISSDEEPFAALAFKIMADPFVGKLAFFRVYSGTLNAGSYVLNATKNKKERVGRILQMHANKREDLDKVYSGDIAAAVGFKFTSTGDTICDEKHPVVLEAMEFPEPVIDVAIEPKTKAGQDKMGEALAKLAEEDPTFRVRTNEETGQTIIAGMGELHLEIIVDRLLREFKVEANVGAPQVAYKEGFTKEVDIDSKYAKQSGGRGQYGHCKVKFSPMDVNGEKVFEFVSTVVGGAIPKEYIPAVQAGIEDAMKCGVLGGYPVLGVRANCYDGSYHEVDSNEMAFKIAGSMAFKDAMHKAGPILLEPIMRVEVTVPDDYMGDVIGDISSRRGRIEGTEDNNGSKIIRGFVPLSEMFGYSTTLRSKTQGRGAYSMFFSTYEPVPKNVQEKVLSNKTK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.