PharMolix/UniProtQA huggingface dataset:
Protein: REI1_CAEEL
Sequence: MTEGDDQLISIRKQLENLNNATDDINSYEMKLETVKKQFCETQLMFNKEMLGIPKKLAKHISKSRQFFDLKSRESEIRRCVQQAAAQFERQKTSVEMAREQVQILHNSLNNNQELDAEKQYVDVIEQQLELVKEAEGECLKAEKCHASRVRDLLQLEMALRKCLEENGSAIKKSRPYYERKEVLTRTMNSQLELMSILEHEVQERKDSYSDSMRALEQISDQIHQERSSQSSLAPSSDAESDSS
What is the function of this protein?
Guanine nucleotide exchange factor for Rab GTPase Rab-11. 1.  Spatially and temporally regulates the distribution of Rab-11. 1 to target membranes during embryogenesis.  Plays a role in cytokinesis, probably by targeting rab-11. 1 to the cleavage furrows.
What are the official names of this protein?
Guanine nucleotide exchange factor rei-1.
What is the protein family that this protein belongs to?
Belongs to the SH3BP5 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Golgi apparatus membrane. Note=Localizes to cytoplasmic granules and to Golgi apparatus membrane in growing oocytes. Co-localizes with rab-11.1 at Golgi apparatus membrane in embryos.
Protein: NPD2_COREF
Sequence: MDEHSIMQAVAVARGARNIEVFTGAGMSADSGLETYRDPETGVWSKVDPQAMASIDAWARDPEPMWAWYRWRAGQAMKARPNAGHETIAYWEGSHLVDAVHVTTQNIDNLHERAGSTEVTHLHGSLFEFRCSICSKPWRDDGDYPREPVERLAPPTCSLCGNPVRPGVVWFGEALPQEEWAVAERRMREADLVVIVGTSGIVYPAASLPVLAHQRGVPILEITPKETDLSRIATYSWRATAAEGLPALVRRLGV
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase 2, Regulatory protein SIR2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ9_XENTR
Sequence: MAASVARVLKAAGGRQLLLMVARRRPVLRQPFLLMPRKFWGTSALRSEDQKQPPFSSTSAHAGTPEHAEEQYQQQQPPPRYTDQAGEESEGYESEEQLQQRILSAALQFVPDFGWSADAIAEGAKSLDMSAAAAGMFEDGGSELVLHFVTQCNSQLTELLEEEQKLVQLGTSEKKPTTQFLRDAVEARLRMHIPYIEQWPQALGMLLLPRNIPSSLKLLTAMVDDIWHYAGDQSTDVSWYTRRAVLTGIYNTTELVMLQDSSPDFEDTWKFLENRISEAMTMGTSVKQVASTGEAVIQGLMGAAVTLKNLTGLNQRR
What is the function of this protein?
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.  Binds a phospholipid of at least 10 carbons in each acyl group.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PIP_CLOD6
Sequence: MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYFEVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLGQSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAVNTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTGTLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVEENEKYIKVLTEWLNAND
What is the function of this protein?
Releases the N-terminal proline from various substrates.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
Protein: TM219_BOVIN
Sequence: MGSCQAGHYLHFCLAHHPPLVCATLILLLLGLSGLGLGGFLLTHRTDLRSPDIPQDWVSFLRSFGQLTLCPVNGTVTGKGRGSHIVGLLTTLNFGDGPDRNKTQTFQAQVQGSRMGLKGSFARELVLVTARVTTERTPGTCLYFSAIPEILPSSQPPIPCSEEGAGNATLSPRMSEECVGVWSHEGLVLTKLLTSEELTLCGSRLLVLGFFLILFCGLCCLTAACFHPRRESHWSRTRL
What is the function of this protein?
Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding.
What are the official names of this protein?
Insulin-like growth factor-binding protein 3 receptor, IGFBP-3R, Transmembrane protein 219.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRPR_ECOBW
Sequence: MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1091_BACFR
Sequence: MFKHLNALFIGLALFACTSGAVAQTIKPIETPVPVRPAGQKDVVGLTTPKLDVVRVGFIGLGMRGPGAVERFTHIPGTQIVALCDLIPERVAGAQKILTKANLPEAASYSGSEDAWKKLCERKDIDLVYIATDWKHHAQMAIYAMEHGKHVAIEVPSAMTLDEIWALINTSEKTRKHCMQLENCVYDFFELTTLNMAQQGVFGEVLHTEGAYIHNLEDFWPYYWNNWRMDYNQNHRGDVYATHGMGPACQLLDIHRGDKMNYLVSMDTKAVNGPAYIKKTTGKEVKDFQNGDQTSTLIRTEKGKTILIQHNVMTPRPYSRMYQVVGADGYASKYPIEEYCMRPTQIASNDVPNHEKLNAHGSVPADVKKALMDKYKHPIHKELEETAKKVGGHGGMDYIMDYRLVYCLRNGLPLDMDVYDLAEWCCMADLTKLSIENSSAPVAIPDFTRGAWNKVKGYRHAFAK
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NDE1_XENTR
Sequence: MDDLENNIFNSVEEEIIYWKSVAMKYKTCSEEAQQELQEFQEASREYEAELEAQLQQIEGRNRDLFSENNRLRMELDGIKEKYEEQHSENYVQICSLEGDLSQTKAVRDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPKSNMGSPETERMDTSVKASVAIPSAPLTPLSQRGCASTLTSPLSFRTSLDDGYSGTPLTPCARISALNIVGDLLRKVGALESKLASCRNFVHEQSPNRPLTSVSARMNKTREGIENRLSMASGSSVEKGLIKRLEFGSLPSNTPVQGMHSPQGVVKMII
What is the function of this protein?
Required for centrosome duplication and formation and function of the mitotic spindle.
What are the official names of this protein?
Nuclear distribution protein nudE homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and to the mitotic spindle.
Protein: Y294_STRP7
Sequence: MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKIYQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTAVADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SP70585_0294.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: GATC_SALSA
Sequence: MYVVVNYTRRLQTLAFNLGSSCYHQGVTGASITSQDRKSKQNFSCCRWTHLITLVHQYSTRISNSKVPRVATWEPVLENQLPPPCQIPVDLVDKLERLALVDFRNQEGLACLEKAIRFADQLHVVDTDGVDPMDSVLEERALYLREDAVAEGDCAEELLQLSKNTVEEYFVAPPGNIPLPKREERAAMLKHSEF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZUP1_MACFA
Sequence: MLSCDICGETVTSEPDMKAHLIVHMENEIVCPFCKLSGVSYDEMCFHIETAHFEQNTLERNFERINTVQFGTSDNKKDNTLQCGMEVNSSILSGCASNHPKNSSQCLTKDSTLKHETFYSENLTESRKFLKSREKQSGLTEVKGSIYETTYGPPECPFCGKIEEHSEDMETHVKTTHANLLDISLEDCDQPLYDCPMCGLICTNYHILQEHVDLHLEENSFCQGMDRVQCSGDLQLAHQLQQEEDRKRRSEESRQEIEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMPPSEFHRRKADMMESLAIGIDDGKTKTSGIIEALHRYYQNAATDVRQVWLSSVVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYDDCLKGMSVPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYILLTSLRVKCHIVDFHKSTGPLGTHPRLFEWILNYYSSEGEGSPKVVCTSKPPIYLQHQGHSRTVIGIEEKKNRTLCLLIFDPGCPSREMQKLLKQDVEASSLKQLRKSMGNLKHKQYQIVAVEGALSPEEKVARRQDSQVFTAEKIP
What is the function of this protein?
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains.  Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains.  Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage.  Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
What are the official names of this protein?
Zinc finger-containing ubiquitin peptidase 1, Lys-63-specific deubiquitinase ZUFSP, DUB, Ubiquitin carboxyl-terminal hydrolase ZUFSP, Zinc finger with UFM1-specific peptidase domain protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family. ZUFSP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mostly present in the nuclear fraction. Localizes to DNA lesions.
Protein: AZOR_METNO
Sequence: MKLLHIDTSILGAGSVSRELSALIVERLTRGTQAEVTYRDLAAENLPHLTPATLPSAHPLSAMAGPLDATAQAARAASDRMLEEFIGADTVVVGAPMYNFTIPSQLKAWLDRLAVPGKTFRYGANGPEGLVGGKRVIVAVTRGGFYGRESGAVSAEHAESYLRTILAFMGITEPEFVLAEGLAAGDHNKAQALTSARAAVQQLAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RSAMH_PYRHO
Sequence: MITLTTDFGLKGPYVGEMKVAMLRINPNAKIVDVTHSVTRHSILEGSFVMEQVVKYSPKGTVHVGVIDPGVGTERRAIVIEGDQYLVVPDNGLATLPLKHIKVKSVYEIIPDKIRKFTGWEISSTFHGRDIFGPAGALIEKGIHPEEFGREIPVDSIVKLNVEPRKEGDVWILKVIYIDDFGNVILNLENYEKPRTVELLDFNLRLPYLETYGLVEKGEMLALPGSHDYLEIAVNMGSAAERLNVKVGDELRVRLL
What is the function of this protein?
Catalyzes the hydrolysis of S-adenosyl-L-methionine (SAM) into adenosine and L-methionine (PubMed:18551689).  Is likely stereoselective, specifically hydrolyzing (R)-S-adenosyl-L-methionine ((R)-SAM), the inactive form of the ubiquitous cofactor SAM, and not the active form of SAM, (S)-S-adenosyl-L-methionine (By similarity).  Probaly plays a role in preventing accumulation of (R)-S-adenosyl-L-methionine in cells; maintenance of (S)-S-denosyl-L-methionine homochirality is important for cellular health given that the (R)-form is largely inactive as a methyl donor and can function as an inhibitor of methyltransferases (By similarity).  Is unable to mediate a fluorination or chlorination reaction with SAM (PubMed:18551689).
What are the official names of this protein?
(R)-S-adenosyl-L-methionine hydrolase, S-adenosyl-L-methionine hydrolase (adenosine-forming), SAM hydrolase (adenosine-forming), S-adenosyl-L-methionine:hydroxide adenosyltransferase, SAM hydroxide adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the SAM hydrolase / SAM-dependent halogenase family.
Protein: MDH_HELGE
Sequence: MTKKITIIGAGNVGATAAXXAASKDLGDIV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: MSRQ_SALEP
Sequence: MRLTAKQITWLKVCLHLAGFLPLLWLFWAINHGGLSADPVKDIQHFTGRTALKFLLATLLVSPLARYAKQPLLIRTRRLLGLWCFVWATLHLTSYALLELGIHNLALLGSELISRPYLTLGIISWLVLLALTLTSTQFAQRKLGKRWQTLHNVVYLVAILAPIHYLWSVKILSPQPVIYAALALALLALRYRRFRQWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOD_RICFE
Sequence: MTNNTKTITLNLGPQHPATHGVLRLILEMDGEVVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPDGLLEDIDKFIEQFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEIDFKVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTDDPKLTPPTRAKMKESMEAMIHHFKLYTEGYDVPAGETYKAVEAPKGEFGVYLYSQGGNRPYRCRIKAPGFAHLQGLDFISKGHLMADVITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CINA_STRPI
Sequence: MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPMVLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVRHIAVMHAFNLVRKALLSD
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL4_BACCQ
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYFA_FRATO
Sequence: MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAVNIAKQALQEAINLKLANFEEQELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFFKQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYIDETHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHVFLNSFFEKDLKVRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEKYQGFAFGMGVERLSMLRYGIDDLRMFFENDLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_DIPDS
Sequence: MTIMRKTHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLVIQIVSGLFLAMHYTPDTLTAFSSVTHICRDVNYGWLIRYMHANGASLFFICLYLHIGRGIYYGSYSYMETWNVGIILLFLVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGADLVEWIWGGFSVDKATLNRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDCDKIPFHPYYTTKDFLGLVILLALFFTLVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILILALLPHIQTASQRSLMFRPISQFLFWLLVSDVLVLTWIGGQPVEPPFIIIGQIASLTYFTIILALMPIAGIIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PANB_XYLFM
Sequence: MSIYTNSKPWTVPALAEAKRNGSKIVMLTAYDAGFARILDANGVDLVLVGDSLGMVVQGHDSTLPVSVHDMVYHTACVARGVRQAMLVVDLPFQADASPERALEAATALLRVGAQMIKIEGAGHKLEVISYLVEREIPVCSHLGLTPQSVLRLGGYKVQGRGEEAGGRLRAEARAAVEAGATLLLLECVPSQLAAQITTDVSVPTIGIGAGAGCDGQVLVLHDLLGLDSGHPRPKFVKDFLAHGGSVAGAVRAYANAVRDGSFPDVEHTYTS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_MYCBT
Sequence: MTVLNRTDTLVDELTADITNTPLGYGGVDGDERWAAEIRRLAHLRGATVLAHNYQLPAIQDVADHVGDSLALSRVAAEAPEDTIVFCGVHFMAETAKILSPHKTVLIPDQRAGCSLADSITPDELRAWKDEHPGAVVVSYVNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRVTGRKNLHVWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPAERVKILSTGGMLEAAHTTRARQVLVATEVGMLHQLRRAAPEVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVHVDPGIAASGRRSVQRMIEIGHPGGGE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_NITWN
Sequence: MTTPDAAIDSKISDSNGADKNKSAADDNAFNAPGRKRHHNNQPRRDKRDVHGWVALDKPVGMTSTQAVAVVKRLFSAKRAGHAGTLDPLASGGLPIALGEATKTVPFVMDGRKRYRFTVAWGEERDTDDTEGRAVATSAERPTAEAIMALLPSFTGKIEQIPPQYSAVKIQGERAYDLARDGEVVPLAPRPVEIHHLNLADHQDSGHSVFEAECGKGTYVRALARDMGRLLGCYGHICALRRTLVGPFDETSMIPLEHLQALCDRAASGEGNLADALLPVETALDDIPALAVTRADAARLHRGQAVLLRGRDAPNMSGTVYVTVAGRLLALAELGNGELIPKRVFNLSGLTASPHRQG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BPIB1_BOVIN
Sequence: MAYPWTFTFLCGLLAANLVGATLSPPVVLSLSTEVIKQMLAQKLKNHDVTNTLQQLPLLTAMEEESSRGIFGNLVKSILKHILWMKVTSASIGQLQVQPLANGRQLMVKAPLDVVAGFNVPLFKTVVELHVEVEAQAIIHVETREKDHARLVLSECSNTGGSLRVSLLHKLSFLLKCLADKVISLLTPAPPKLVKSELCPVLKAGFEDMRGELLNLTKVPMSLNSEHLKLDFISPVIDHSVVHLILGARLFNSEGKVTKLFNVAGDSLNLPTLNQTPFRLTVRKDVVVAIIAALIHSGKLTVLLDYVLPEVARQLRSSIKVIDETAAAQLGPTQIVKIMSQTTPMLILDQGNAKVAQLIVLEIFATDKDSRPLFTLGIEASSDIQFYVEDGLLVFSFNEIRADRIHLMNSDIGVFNPKLLNNITTKILTSILLPNENGKLRSGIPVSMVKNLGFKSISLSLTKEALVVTQASS
What is the function of this protein?
May play a role in innate immunity in mouth, nose and lungs.  Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity).
What are the official names of this protein?
BPI fold-containing family B member 1, Long palate, lung and nasal epithelium carcinoma-associated protein 1, von Ebner minor salivary gland protein, VEMSGP.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
What are the subcellular locations of this protein?
Secreted.
Protein: NR0B1_MACMU
Sequence: MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVSLLYRCCFCGKDHPRQGSILYSMLTNAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRTGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSAKQTHVAPAAPEARPGGAWWDRSYFAQRPGGREALPGGRAMGLLYRCCFCGEDHPQQGSTLYCMPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKNPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGDEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKL
What is the function of this protein?
Orphan nuclear receptor.  Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis.  Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions.  May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 0 group B member 1, Nuclear receptor DAX-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus (By similarity).
Protein: EFTU_STAAE
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.