PharMolix/UniProtQA huggingface dataset:
Protein: FHUB_BACSU
Sequence: MHFHFCSKHSIKSAEKSDILKQQLIIIISNRKEVRQLSQHKNIRTASEEIQWTSRTYGAVIVLIAGLCLLCLGAFLSISLGAADIHLRTVWEAIFHYQPTKTSHQIIHDLRLPRTAAAALVGALLAVSGAIMQGMTRNPLAEPSIMGVTSGSAFAVSIAFAFFPGLSAMGLVLWSFAGAGLGASTVMGIGMFSRGGLTPVKLALAGTAVTYFFTGISTAIAIRFDVAQDISFWYAGGVAGVKWSGVQLLLIAGAVGLTLAFFIARSVTVLSLGDDLAKGLGQYTSAVKLVGMLIVVILTGAAVSIAGTIAFIGLIIPHITRFLVGVDYRWIIPCSAVLGAVLLVFADIAARLVNAPFETPVGALTSLIGVPFFFYLARRERRGL
What is the function of this protein?
Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import.  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Iron(3+)-hydroxamate import system permease protein FhuB, Ferric hydroxamate uptake protein B, Ferrichrome transport system permease protein FhuB, Iron(III)-hydroxamate import system permease protein FhuB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: FLIF_BUCAI
Sequence: MNFSTIEESVLKEKKKFNNFLSGFLKNSRFLIILLTAAAITAVSISVWIKSPEYQVLYNHLSNEDRGSIINELNEMKIPYQFTDSDGPILVPKDKVYEIRLRLAENNLPRGGSIGFELLDKEKFGISQYNEQINYHRALEGELARTIKKINSVKNARIHIAFSKSSLFLQDKKKSSASIILELQPGRNLNTGQINAIMHLISSSISDLPVENITIVDQSGKLLNQTSVEYDQVNDSQFKYTEEIETRYRNRIKNILEPLVGIGNIYAQVTAQIDFNAQEKTQEKYSPNSDHKNQSIRSHQIIIHNEIEKSNIQEETPIPLSNSNNHVYFNNNIKNSKNLKNNYIPVDSKINRDNTVNYELNHSVSHTKMNIGEIKRLSAAVIVNFSKDKNGKFVPLSTQKIKNIEHLIREAIGYSKARGDSVHLVNASFAKYDQKIPVHINHINTFRKSNFLYNFAPWFCSFALLFLLLKKYICPFSKNNTFQNTIPVQEKKSIDTRNIIEKNTFQVDLQNNTNTDKLIHKICNISNQNPRTIALIIRQWMSDKI
What is the function of this protein?
The M ring may be actively involved in energy transduction.
What are the official names of this protein?
Flagellar M-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FliF family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: PRO_HTLV2
Sequence: MGQIHGLSPTPIPKAPRGLSTHHWLNFLQAAYRLQPRPSDFDFQQLRRFLKLALKTPIWLNPIDYSLLASLIPKGYPGRVVEIINILVKNQVSPSAPAAPVPTPICPTTTPPPPPPPSPEAHVPPPYVEPTTTQCFPILHPPGAPSAHRPWQMKDLQAIKQEVSSSALGSPQFMQTLRLAVQQFDPTAKDLQDLLQYLCSSLVVSLHHQQLNTLITEAETRGMTGYNPMAGPLRMQANNPAQQGLRREYQNLWLAAFSTLPGNTRDPSWAAILQGLEEPYCAFVERLNVALDNGLPEGTPKEPILRSLAYSNANKECQKILQARGHTNSPLGEMLRTCQAWTPKDKTKVLVVQPRRPPPTQPCFRCGKVGHWSRDCTQPRPPPGPCPLCQDPSHWKRDCPQLKPPQEEGEPLLLDLPSTSGTTEEKNLLKGGDLISPHPDQDISILPLIPLRQQQQPILGVRISVMGQTPQPTQALLDTGADLTVIPQTLVPGPVKLHDTLILGASGQTNTQFKLLQTPLHIFLPFRRSPVILSSCLLDTHNKWTIIGRDALQQCQGLLYLPDDPSPHQLLPIATPNTIGLEHLPPPPQVDQFPLNLSASRP
What is the function of this protein?
The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell (Potential).  Cleaves the translation initiation factor eIF4G leading to the inhibition of host cap-dependent translation (By similarity).
What are the official names of this protein?
Gag-Pro polyprotein, Pr76Gag-Pro.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-pro]: Virion.
Protein: NU3M_ALLCE
Sequence: MSEFSPIFIYLVMSLLVSLILLGLPFLFASNSSTYPEKLSAYECGFDPFGDARSRFDIRFYLVSILFIIFDLEVTFFFPWAVSLNKIDLFGFWSMMAFLLILTIGFLYEWKRGALDWE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SGSM3_HUMAN
Sequence: MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG
What is the function of this protein?
May play a cooperative role in NF2-mediated growth suppression of cells.
What are the official names of this protein?
Small G protein signaling modulator 3, Merlin-associated protein, RUN and TBC1 domain-containing protein 3, Rab-GTPase-activating protein-like protein, RabGAPLP.
What is the protein family that this protein belongs to?
Belongs to the small G protein signaling modulator family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPC5_DANRE
Sequence: MEIRVGSAVFSSRFDSGNLARVERVEASEAAGESSRSASVPQPDYEFNVWTRPDCASTEFENGNRSWFYFSVRGLLPGKLLKINMMNMNKQSKLYTQGMAPFVRTLPVKTRWERVRDRPTFEMSDSQFILSFVHRLLDVRGVTTYFSFCYPFSYAECQDMMLQLDHKFLSSTSTHTACSPPESIYYHRELLCHSLDGHRVDLITVSSCHGLLEEREPRLDKLFPDLSTARSHRFTGKRVFFVSSRVHPGETPSSFVFNGFLNFILSQEDPRAQTLRRMFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYVNPSPDLHPSIYGAKSLLLYHHIHNRLGHASGSALKTSNQSNTSPPVATPTERERCMNLRNEAERGEGPTFDLSEIPMQLEESWEKSGVQREAEHSDENESAQSRGETNSAPSEQVPPQESGVAYYIDLHGHASKRGCFMYGNNLTEESQQVENMLYAKLISLNCAHFDFLGCNFSEKNMYARDKRDGQSKEGSGRVAIHKAIGLVHSYTLECNYNTGRSVNTIPPACHDNGRATPPPPPAFPPKYTPEVYEQVGRAVAVAALDMAECNPWPRLVLSEHSSLLNLRASILKHVRNSTGLTSNNRRNTHCKTSSSPPKPVSLSTSASENSLNRTRSTTNVQGSRQTPQLKSSPSFTFGTTAHRPSHRSLGPVRECKAQEKRRPPPPPLPHHHHQQHQRLSVRLSAPVRAPLSPSSSSSSSSSSPSSSSSAPGPGSISLAGNSCPEFRPANQIKELRGGRGKGGRSGPAYCHSSQQRTALTTKEPLQDSLDILTSIEYSRCELQPRPSRIPVRRELQSSVIPLSSTETPTMRVWKLIKPGLKKHLAGVSGKDRLSTKALLKNSSRQTDQHIHRSLPT
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin.  Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate.  Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin.
What are the official names of this protein?
Cytosolic carboxypeptidase-like protein 5, ATP/GTP-binding protein-like 5, Protein deglutamylase CCP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody.
Protein: RR19_SOLBU
Sequence: MTRSLKKNPFVANHLLKKIDKLNTKAEKEIIVTWSRASTIIPTMIGHTIAIHNGKEHLPIYITDSMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRA1D_ARATH
Sequence: MANQVITGIKETAQSITGAARPWGDFLDLSAFSFPSSIADATTRVTQNLTHFRINYSIILSILLGLTLITRPIAILAFIAVGLAWFFLYFAREEPLTIFGFTIDDGIVAVLLIGLSIGSLVTTGVWLRALTTVGFGVLVLILHAALRGTDDLVSDDLESPYGPMLSTSGGGNDGARGDYSGI
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein D, AtPRA1.D, CAMV MOVEMENT PROTEIN-INTERACTING PROTEIN 7, Prenylated Rab acceptor 5.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: PG142_VACCC
Sequence: MFVDDNSLIIYSTWPSTLSDSSGRVIVMPDNRSFTFKEGFKLDESIKSILLVNPSSIDLLKIRVYKHRIKWMGDIFVLFEQENIPPPFRLVNDK
What is the function of this protein?
Late protein which is a part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.  Required for the stability and kinase activity of OPG054.
What are the official names of this protein?
Core protein OPG142.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG142 family.
Protein: KADA_METMJ
Sequence: MLGKKVVVTGVPGVGKTTVINGAMERLATEGVAYKAVNFGTFMFEVAKKENLASDRDEMRKLEKDVQKRLQQAAATGIAAMSGEANIIIDTHSTVKTPTGFLAGLPEWVLRELMPDIVVLVETDPDQILMRRLGDASRARDMEGYRAIAEHQEFNRAVSAAYAMYTGCTIKIVRNENFLLEQGIDDLVSVLR
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_LACJO
Sequence: MTTRYKLTMAYDGHLFHGFQIQPNQRTVQGVIEEALKKMTKGKRVVVHGSGRTDAGVHAKGQVIHFDYPGKEIPAKNMMLALNALMPIDTVFFESEIVDEDFHVQYSTKGKWYRYVVDQHRFTDPFNRFYTGHYPYPLDISLMKQAAKDLIGEHDFTSFAASGGQIVDKVRTIYYVNITPDPDKKQIIFDFIGNGFLYNMVRILVGTLLEIGNKKRPVDDIPRVLKAKDRQEVRTTAPASGLYLQQVFYEDIPKKYRLDLKKD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: COQ4_DROWI
Sequence: MMQRLRLARRGLALSAVRRQTVVPEEEPLDAYEREHLKHRIEITPFQRMLLGAGSSVAAILDPRRHDMIACLGETTGEGALWNILDTMEASEEGQRILIDKPRIHTSTIDFKRLETLPPDTFGAAYVKFLKDNNVTPDSRMPVRFLEDPKLAYLMTRYRECHDLIHTVLNMPTNMLGEVAVKWVEALNTNLPMCYGGAVFGAVRLRPKQRREYLKRYLPWAIDNGKRMKPLMPVYWEQRWEQNLDLAKKTSPIMLPALRITRRDG
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL27A_PIG
Sequence: MPSRLRXTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHXGYFG
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L27a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDKAL_HUMAN
Sequence: MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDLSRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIYESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDSASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYN
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase, CDK5 regulatory subunit-associated protein 1-like 1, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Is a tail-anchored protein that exploits the TCR40 pathway for insertion into the endoplasmic reticulum.
Protein: MTGA_RHOPS
Sequence: MKRAIRAAILTVLVLLAAPYVLTLLYGAGQPVSTLMIWRWLTGATVTREWVDIERISPALPRTVVASEDAKFCSHRGIDWDSVRDVIDDMQDGEATRGGSTITQQVAKNLFLWPGRSMVRKALEFPLALWIDLVLSKQRVLELYLNIAEWGPDGQFGAEAGAQYAFGRSAGQLTAQEAALMASILPNPRTRSARKPGRGVRRLAATYVARARSAELQQCWRENSALSGN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CELE_ACET2
Sequence: MKKIVSLVCVLVMLVSILGSFSVVAASPVKGFQVSGTKLLDASGNELVMRGMRDISAIDLVKEIKIGWNLGNTLDAPTETAWGNPRTTKAMIEKVREMGFNAVRVPVTWDTHIGPAPDYKIDEAWLNRVEEVVNYVLDCGMYAIINVHHDNTWIIPTYANEQRSKEKLVKVWEQIATRFKDYDDHLLFETMNEPREVGSPMEWMGGTYENRDVINRFNLAVVNTIRASGGNNDKRFILVPTNAATGLDVALNDLVIPNNDSRVIVSIHAYSPYFFAMDVNGTSYWGSDYDKASLTSELDAIYNRFVKNGRAVIIGEFGTIDKNNLSSRVAHAEHYAREAVSRGIAVFWWDNGYYNPGDAETYALLNRKTLSWYYPEIVQALMRGAGVEPLVSPTPTPTLMPTPSPTVTANILYGDVNGDGKINSTDCTMLKRYILRGIEEFPSPSGIIAADVNADLKINSTDLVLMKKYLLRSIDKFPAEDSQTPDEDNPGILYNGRFDFSDPNGPKCAWSGSNVELNFYGTEASVTIKSGGENWFQAIVDGNPLPPFSVNATTSTVKLVSGLAEGAHHLVLWKRTEASLGEVQFLGFDFGSGKLLAAPKPLERKIEFIGDSITCAYGNEGTSKEQSFTPKNENSYMSYAAITARNLNASANMIAWSGIGLTMNYGGAPGPLIMDRYPYTLPYSGVRWDFSKYVPQVVVINLGTNDFSTSFADKTKFVTAYKNLISEVRRNYPDAHIFCCVGPMLWGTGLDLCRSYVTEVVNDCNRSGDLKVYFVEFPQQDGSTGYGEDWHPSIATHQLMAERLTAEIKNKLGW
What is the function of this protein?
Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides.  Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan (PubMed:3066698, PubMed:1991028).  Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) (PubMed:19338387).
What are the official names of this protein?
Cellulase/esterase CelE, CtCel5C-CE2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPL_OCEIH
Sequence: MGALAAAIAIGLAALGAGLGNGMIVSKTVEGIARQPELRGALQGTMFIGVALVEAIPIIAAVIAFMVM
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROA_DESOH
Sequence: MTIEATIVDIAKAAKKAALAMATCPTDKKNQALLALADRLHKDAALIQAENKKDLEAAKATGLSSAMIDRLTVSDAVIASMADGLREVAALPDPVGAKSATWRRPNGLEVARMRIPLGVIGIIYESRPNVTVDAAGLCLKAGNTVILRGGSEALHSNRALAATISASLAESGLPETAVQVVPVADREAVTHLLAQEEYIDLIIPRGGEGLIRFVVQHSSIPVLKHYKGVCHVYVDQDADMEMARAICFNAKVQRPGVCNAMETLLVHRDAAQRFLPDMARQFADAGVALRGCAATRALLPGIETAEEADWYAEYLDLILAVKVVDSMDAAISHIATYGSSHTEVIVTNSYDRAMRFLAAVDSSVVLVNASTRFNDGGQLGLGAEIGISTSKLHAFGPMGLEELTTTKFIVLGNGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_SHISS
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDGETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAB_METKA
Sequence: MFDPKKFVEEAIEELRREIGDRKAIIAVSGGVDSTTAAVLTHRAIGSHLVCVFVDHGFMRKGEPERIRELLEEELGLNLRFVEAAEEFFEALRGVTDPEEKRKIIGEKFIEVFERIAEEEEAEVLVQGTIAPDIIESERGIKSHHNVGGLPEKLNLDVVEPLRDLYKDEVREVARYLGIPDEIVERMPFPGPGLAVRVLGEVTPEKVEIVREANAIVEEEVEKAVEEGKMSKPWQAFAALLDCKATGVKGDERDYGWVIAVRIVESIDAMIADVPEVPWEVLRNIQDRITSEVPEVTRVLFDITPKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: MURA_SHEB5
Sequence: MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCLGAEVTELGDGQIRISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSFLVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQGTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIENKFQGLGAQVVRTQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_YERPN
Sequence: MNFPIERVRADFPLLSRQVNGQPLVYLDSAASAQKPQAVIDKELHFYRDGYAAVHRGIHSLSAEATQQMEAVRTQVADFIHAASAEEIIFVRGTTEAINLVANSYGRHFLAAGDSIIITEMEHHANIVPWQMLAQDLGVEIRVWPLTATGELEITALAALIDDTTRLLAVTQVSNVLGTVNPIKDIVAQAKAAGLVVLVDGAQAVMHQPVDVQALGCDFYVFSGHKLYGPSGIGILYGKSALLQQMPPWEGGGAMIKTVSLTQGTTFADAPWRFEAGSPNTAGIMGLGAAIDYVTELGLLPIQQYEQSLMHYALAQLSQIKSLTLYGPTERAGVIAFNLGQHHAYDVGSFLDQYGIAIRTGHHCAMPLMAFYQVPSMCRASLALYNTREDVDRLVAGLQRIEKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_HELPJ
Sequence: MQQEEIIEGYYGASKGLKKSGIYAKLDFLQSATGLILALFMIAHMFLVSSILISDEAMYKVAKFFEGSLFLKAGEPAIVSVVAAGVILILVAHAFLALRKFPINYRQYKVFKTHKHLMKHGDTSLWFIQALTGFAMFFLASIHLFVMLTEPESIGPHGSSYRFVTQNFWLLYIFLLFAVELHGSIGLYRLAIKWGWFKNVSIQGLRKIKWAMSVFFIVLGLCTYGAYIKKGLENKDNGIKTMQEAIEADGKFHKE
What is the function of this protein?
The fumarate reductase enzyme complex is required for fumarate respiration.  This subunit anchors the complex in the membrane and binds a diheme cytochrome b.
What are the official names of this protein?
Fumarate reductase cytochrome b subunit, Quinol-fumarate reductase cytochrome b subunit, QFR cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the diheme cytochrome b FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_LAWIP
Sequence: MASKEILFDAKAREKLSRGVDKLANAVKVTLGPKGRNVVIEKSFGSPVITKDGVSVAKEIELEDKFENMGAQMVKEVASKTSDIAGDGTTTATVLAQAIYREGVKLVAAGRNPMAIKRGIDKAVVAVTKELSDITKPTRDQKEIAQVGTISANSDTTIGNIIAEAMAKVGKEGVITVEEAKGLETTLDVVEGMKFDRGYLSPYFVTNPEKMVCELDNPYILCNEKKITSMKDMLPILEQVAKVNRPLLIIAEDVEGEALATLVVNKLRGALQVVAVKAPGFGERRKAMLEDIAILTGGEAIFEDRGIKLENVSLSSLGTAKRVVIDKENTTIVDGAGKSEDIKARVKQIRAQIEETSSDYDREKLQERLAKLVGGVAVIHVGAATETEMKEKKDRVEDALNATRAAVEEGIVPGGGTAFVRSIKVLDDIKPADDDELAGLNIIRRSLEEPLRQIAANAGYEGSIVVEKVREAKDGFGFNAASGEYEDLIKAGVIDPKKVTRIALQNAASVASLLLTTECAIAEKPEPKKDMPMPGGGMGGMGGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.