PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_RHOCS
Sequence: MSETAAPAAKTLAPAPKVGIVSLGCPKALVDSERILTKLRSEGYEISGSYDGADVVLVNTCGFLDSAKTESLDAIGEAIKENGRVIVTGCLGKDAELIRETHPQVLAVTGPHQYEQVVAAVHDVVPPRHDPYLDLVPPQGLRLTPRHYAYLKISEGCNNRCTFCIIPSIRGDLVSRPANLVLAEAEKLVKAGVKELLVVSQDTSAYGVDLKYAESRHRNRPVRARFLDLCQELGQLGAWVRLHYVYPYPHVDEVIPLMAEGKVLPYLDIPFQHASPRVLKAMRRPADHERILERIKGWRAGCPDLTLRSTFIVGFPGETEEDFQFLLDWLTEAQIDRLGCFQYEPVTGAKANGIPGAVPDEVKEERWHRLMQHQQAISDARMQARIGRSIEVLIDEVDEDGATGRSWADAPEIDGNVFLNGETDLKQGDLVKATVFATDAYDAWAERD
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM2_XENLA
Sequence: MADSSESFNIATSPRAGSRRDALTSSPGRDLPPFEDESEGMFGDGVVPEEEEDGEELIGDAMERDYRPISELDRYEVEGLDDEEDVEDLTASQREAAEQSMRMRDREMGRELGRMRRGLLYDSDEEEEDRPARKRRMAERAAEGAPEEDEEMIESIENLEDMKGHTVREWVSMAATRLEIYHRFKNFLRTHVDEHGHNVFKEKISDMCKENKESLPVNYEDLAAREHVLAYFLPEAPAEMLKIFDEAAKEVVLVMYPKYDRIAREIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTCCTGVLPQLSMVKYNCNKCNFILGPFFQSQNQEVRPGSCPECQSFGPFEINMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHITKKDDKVAVGELTDEDVKAIVALSKDERIGERIFASIAPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAASNPIGGRYDPSLTFSENVDLTEPIVSRFDILCVVRDTVDPVQDEMLARFVVSSHIKHHPSSKDIANGDAAEFALPNTFGVEALPQEVLKKYIMYAKEKIRPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVVEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLAFRRDNNELLLFVLKQLIAEQVTYQRNRYGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSDLFKMNKFTHDVKKKLIIQQF
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  Required for the entry in S phase and for cell division.
What are the official names of this protein?
DNA replication licensing factor mcm2, BM28-homolog, Minichromosome maintenance protein 2, xMCM2, p112.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
Protein: SCPA_STRP4
Sequence: MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEIITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: SYNPO_RAT
Sequence: MLGTHFPPPPLGPSEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEEEGTSKSRVNHGTPPLSRAPAIIQPSSCCREARGGFQHSDKPSREWDVVQARKVMTASVSSSPVPRVAQKPALGRSTSFTEKDLKEAKERSQRIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLSQEALQTGHPSSPIGHAPGLSVNPTSPSKPGSPKHSSSQSPSRGVPGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNRETQQSSPNPPETEEVPSPAADINQNPSSPNATLTTAASNSHHNQPTADVNQNPPATITPVQQNSSETQCSPNGTLDSKPNTPSADDGQRPVPAEEVRSSILLIDKVSAPPSAASPFSREATPLSSSGPPAADLMSSSLLIGMQPSTLVASAEQEVSGHAAVTTPTKVYSEVHLTLAKPASVVNRTARPFGMQSPGTTSQIEQSPMMGRRHFGEKAWAPPASSMADRSPQPQRHIMARSPMVERRLVGQRSPVVERRPLGNFTPPPTYAETLSTAPVASQVRSPPSYSTLYPSSDPKPPHLKGQVVPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGMEDEPFALGAEASNFQQEPIARDRSGPAAAEETVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHAELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPHQMRPSLYALSPVKEPAKISSRATSSRASSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYNAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK
What is the function of this protein?
Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes.  Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
What are the official names of this protein?
Synaptopodin.
What is the protein family that this protein belongs to?
Belongs to the synaptopodin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, tight junction. Perikaryon. Cell projection, dendritic spine. Postsynaptic density. Synapse. Cytoplasm, cytosol. Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses (PubMed:9314539).
Protein: CBPM_STRAL
Sequence: MRPRPIRLLLTALVGAGLAFAPVSAVAAPTATASASADVGALDGCYTWSGTLSEGSSGEAVRQLQIRVAGYPGTGAQLAIDGQFGPATKAAVQRFQSAYGLAADGIAGPATFNKIYQLQDDDCTPVNFTYAELNRCNSDWSGGKVSAATARANALVTMWKLQAMRHAMGDKPITVNGGFRSVTCNSNVGGASNSRHMYGHAADLGAGSQGFCALAQAARNHGFTEILGPGYPGHNDHTHVAGGDGRFWSAPSCGI
What is the function of this protein?
This enzyme catalyzes carboxypeptidation and transpeptidation reactions involved in bacterial cell wall metabolism.  It effectively catalyzes the transfer of the N-alpha, N-epsilon-diacetyl-L-lysyl-D-alanyl electrophilic group of the standard tripeptide substrate N-alpha,N-epsilon-diacetyl-L-lysyl-D-alanyl-D-alanine to water.  It also performs a weak beta-lactamase activity, hydrolyzing penicillin into penicilloate at a very low rate.
What are the official names of this protein?
Zinc D-Ala-D-Ala carboxypeptidase, D-alanyl-D-alanine carboxypeptidase, Metallo DD-peptidase, Zn DD-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M15 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSA_MYCSJ
Sequence: MGAHHTATEQSARLFADACAVIPGGVNSPVRAFNAVGGTPRFITSANGYWLTDADDNRYVDLVCSWGPMILGHAHPAVVEAVQRVAADGLSFGAPTPSETELASEIISRVAPVERLRMVNSGTEATMSAIRLARGFTGRPKIVKFSGCYHGHSDALLADAGSGVATLGLPSSPGVTGAATADTIVLPYNDVDAVDEIFEQVGDQIAAVITEASPGNMGAVPPEPGFNAALRRITEEHGALLILDEVMTGFRVSRSGWYGLDPVDGDLFTFGKVMSGGLPAAAFGGRAEVMERLAPLGPVYQAGTLSGNPVAMAAGLATLRTADDAVYAALDKNADRLAGLLTDALTDAGVTHRVQRGGNMLSVFFTAEPVGDFATARASETWRFPPFFHALLDAGVYPPPSAFEAWFVSAALDDEAFDRIAAALPGAARAAAEASRPA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RARA_XENLA
Sequence: MSSKDNTCPPPGPGHINGFHVPHYAFFFPHMLGGMSXTGGLPGVQHQPPLSGYSTPSPATIETQSTSSEEIVPSPPTPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKESPKPEAIESYILSPETQDLIEKVQKAHQETFPALCQLGKYTTSFSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKSACLDILILRICTRYTPDQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQPVPLEMDDAETGLLSAICLICGDRQDLEQPDKVDKLQEPLLEALKIYVRTRRPQKPHMFPKMLMKITDLRTVSAKGAERVITLKMEIPGAMPLIQEMLENSEGLDTLGGGASSDAPVTPVAPGSCSPSLSPSSTHSSPSTHSP
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity).  Required for primary neurogenesis and for anteroposterior neural patterning.
What are the official names of this protein?
Retinoic acid receptor alpha, RAR-alpha, Nuclear receptor subfamily 1 group B member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTB_XENBS
Sequence: MHSDSPMTGGGPSRLFILRPVATTLFMIAILLAGIIGYRMLPVSALPQVDYPTIQVVTLYPGASPDIMTSVVTAPLERQFGKISGLKQMTSQSSGGASVITLVFQLSLPLDVAEQDVQAAINAATNLLPNDLPYPPIYSKVNPADPPILTLAVTSDALPMIQVQDMVETRIAQRISQVGGVGLVTLAGGQRPAVRVKFNAQAIAAHGLNSETIRTTIMNANVSSAKGSFDGPTRSVTLTTNDQMKSIDEYRNLIVAYKNGAPIRLRDVATIERGAENTKLGAWANEKPAIVINVQRQPGANVIDTTDNIRAMLPELINSLPKSVNMDILTDRTVTIRASVQDVQFELLLAIALVVMVIYVFLRNATATLIPSIAVPLSLVGTFAVMYFCGFSVNNLTLMALTIAAGFVVDDAIVVIENISRYIERGEKPMAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLKAEAEIKHNRFEQASEHFFERIIAIYGGWLKRVLNHPWITLGVAFSTLAFTALLYLTIPKGFFPLQDNGLIQGTLEAPQSISFNAMSDKQREVTALLLQDPDVENVTTFIGVDGSNSTLNSGRLQITLKPLNQRDIRVDEIIPRLQARVANVPDVKLYLQPTQDLTIDTQVARTQYQFTLQGTVSNDLNIWVPKLQEALKQRPELVDVGTDWQNRGLVAYINVNRDMASRLGISMTAIDNALYNAFGQRLISTIYTQANQYRVILEQDTQNEAGMNAFNNVHLIGTDNKVVPLSTIATVEQQLGYLSINHLQQFPAVTFSFNVAQEASLEAAVNAVKETERSIGMPKNINTQFQGATLAFQDALGNTLWLILAAVISMYIVLGILYESFIHPVTILSTLPTAGVGALLALMVGGYELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREKGMSPYDAIFQACLLRFRPILMTTMAALLGALPLMLSTGIGAELRRPLGICMVGGLIMSQILTLFTTPVIYLLFDRLANYFKNKRQNRLQSQNQRELDHSPVNHQEPL
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCXA_TRICV
Sequence: MKIFLYLLRKKIAEVWIFQNPANFLSL
What are the official names of this protein?
Uncharacterized 3.3 kDa protein in rpl11-trnW intergenic region, ORF27.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_LEUCK
Sequence: MTKIAVLGAGSWGTALANTAAENGHDVRLWTHHSDQAVEINHNKTNTKYLPDATLSEQLFATDDMAVAVKDSDIVLCVVPTKAVREVAKQLADTLAQLNHQVILAHATKGLEQGTYKRISEMLSEEIPETYRSALVVVSGPSHAEDVIKHDLTAVSIGGSDENATKLLQRVLSNKTFRAYTNHDLLGSELFAALKNIVAIGSGALVGLGYGANAQAALLTRSLVEMRQLGLAMGAQEKTLYELAGIGDLIVTGMSPNSRNYRAGLGLGQGKSLKQVSDDMGMVIEGVNTTKAVYDFSQQYHVDMPITKAIYQVLYDNKPLSEAINDLMSRPLKSEDAL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTH_ERWT9
Sequence: MSESRTVERSVRSNRKIKFALMGPAFIAAIGYIDPGNFATNIQAGASYGYQLLWVVVWANVMAMVIQLMSAKLGIATGKNLAEHIRDRFPRPAVWFYWVQAEIIAMATDLAEFIGAAIGFKLVFGVTLLQGAMLTGVATFLILMLQNRGQKPLELVIGGLLLFVAAAYVIELFFSQPKVVDLLQGMAVPSLPTADAVLLAAGVLGATIMPHVIYLHSSLTQNSGDQGSRSERYSSTKLDVAIAMTIAGFVNLAMMATAAATFHFSGHSGVADLDQAYLTLDPLLGKAAALVFGLSLLAAGLSSTVVGTMAGQVVMQGFIHFHIPLLLRRVITMLPSFIVILAGWEPTRILVMSQVLLSFGIALALIPLLAFTGNPGLMGDMVNSRLMQNFGRLIVVVVIALNGYLLVAMALNL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAPP_YERPN
Sequence: MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: Y253_BUCAI
Sequence: MKIIKVTVVYALPKIQYICQVDIALGSTVKDAILKSNLLNLTNDVSFHHNRIGIYNKTVHLKFKIKDGDRIEIYRNLTIDPKEWRRNNVFLSKKLKKIY
What are the official names of this protein?
UPF0125 protein BU253.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RNPA_MARN8
Sequence: MKALTFPKSHRLLKPSDYSRVFNDVTLKVPHRNFLILASANSLGHARVGLIFSKKNLRLAVQRNRIKRQVRETFRLQPDLPGLDIIVLGRQGLDRLDNDTVRSSLNDLWHRVKKKYRQSTPDQSVGNPRGTE
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS16_SYNAS
Sequence: MAVKIRLARMGAKKKPFYRIVVSDSESPRDGRFLEIVGNYDPGKDPAEVNVKESRLLEWLSKGAKPTLTVSQLLQKKGIKVGA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: U31H_SCYTH
Sequence: MSQNSITSYKMGFAKHFFLFAVLLCATAMYSVAEPAQERLIESIACMQKGLPCMEHVDCCHGVCDSLFCLY
What is the function of this protein?
Probable insect neurotoxin with ion channel impairing activity (Probable).  Does not show activity on 45 human receptors from 9 families (5-hydroxytryptamine, adrenergic, dopamine, muscarinic, histamine, neurotransmitter, opioid, sigma, and gaba(A) receptors) (PubMed:27227898).  In vivo, when mixed with U3-SYTX-Sth1a does not cause paralytic or lethal activity when injected into crickets (PubMed:27227898).  It is noteworthy that crickets are evolutionarily distant from prey species (PubMed:27227898).
What are the official names of this protein?
U3-scytotoxin-Sth1h, U3-SYTX-Sth1h, U3-Sth1h.
What are the subcellular locations of this protein?
Secreted.
Protein: ERMA_STAAN
Sequence: MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Erythromycin resistance protein, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: SRS10_HUMAN
Sequence: MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH
What is the function of this protein?
Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing (PubMed:11684676, PubMed:12419250, PubMed:14765198).  Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70 (PubMed:14765198).  Required for splicing repression in M-phase cells and after heat shock (PubMed:14765198).  Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing (PubMed:26876937).  Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (PubMed:26876937).  May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator (PubMed:12419250).
What are the official names of this protein?
Serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, SRrp40, FUS-interacting serine-arginine-rich protein 1, Splicing factor SRp38, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
Protein: SYR_LISMF
Sequence: MNVMQENQIKLIEHIKQAVVQAVGLEEAEVPEILLEVPKDKKHGDYSTNIAMQLARVAKKAPRQIAESIVPELKKDNKLIKEVEIAGPGFINFYLDNAYLTDLVPVILTEDKQYGESDFGKGEKFQIEFVSANPTGDLHLGHARGAAIGDSLANIMKMAGFDVSREYYINDAGNQINNLVLSAEARYFEALGLDSEFPEDGYRGADIISLGKDLAAKYGDKYVHTSEEERRSVFRVDALAFETGKLRADLEEFRVSFDEWFSETSLYEENKVLPALERLRENGYIYEQDGATWLRTTDFEDDKDRVLIKSDGSYTYFLPDIAYHLNKLERGFDVLIDIWGADHHGYIPRMRAAIEALGYSPNQLEVEIIQLVHLFEDGVQVKMSKRTGKSVTMRDLIEEVGLDATRYFFAMRSSDTHMNFDMSLAKSTSNDNPVYYVQYAHARISSILRSGKEQGLEVTKDADMSLLQTEAEYDLLKVLGEFADVVAEAATKRAPHRIVRYLNDLASSFHRFYNSNKVLDMDNLEVTKARLALIKTAQITLRNGLTLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANE_EMENI
Sequence: MKFSQLILPFSAALSLVGSGVATPTTKPVNPRASRPARNLLAHLVRSAGNGTTLSGQQELKDADWVTDNVGFSPVILGVDLMDYSPSRVEFGAVSTSIEDAITYATQGGIITICWHWGELSHDWMTDERLTTLLTLGSPSGTYNTTEQPWWSNFYTEATSFNLSAAMNPASRDYKLILRDIDAIAEQLARLKDIPVLFRPLHEAEGGWFWWGATGAEPCKALYRLLFDRLTKKHGLNNLLWVWNSKDPLWYPGNEYVDVVSVDVYADNGDHSSQLEAYQALQGLTGNFSKLIALGEVGNIPDPELMREDGAQWAYWVTWNGDFIRGETKNPMEFKKAVYASELVYTLDEIQGWNL
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase E, Endo-beta-1,4-mannanase E.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 26 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_CAMLR
Sequence: MRANVLKRKLSLRIKRKKRIRAKISGTQALPRISVFKSNRTLYIQAIDDVKAVTLAAVDGRKIGVKANKEGAKKIAAEFAKALKAKNIEEAVFDRNGYLYHGVIAVLAEALRENGIKL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL4_DESAP
Sequence: MPTAAVFNIEGQQVGEIELSEAVFGQPVNDAVLHEVVVMQLANRRQGTHDTKTRSEVRGGGRKPWRQKGTGRARHGTIRSPIWRGGGIVFGPHPRDYSYRVPKKVKRLALKSALATKVDAGRILVLDALELPGPKTKEMARILANLKAGEGALVVTAERNVNVEKSARNLPGVKSLEARQLNVYDLLNHPHLIITRDAVARVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SIP5_VANPO
Sequence: MGNVPTKLEEPQNPSSRLKSSSFSNSVSGNSDITDSPGSGNGRSSSQTKLNNARSKKKNASLSNGLLKSTTISSRKKDQLDREQFKEDHAAELLVKYYESVDGGFLAPFGCYSLEKLNYNPKIVKKLIIERKLAPFYTPLQDFNDNWTDEELIKIIDGLPLHASFNESLEEFEDIPTGDLKSKDFDYLIDSSSLSKREQKKLHSKIFKARLHKKRIAWQEMENTYFLEKKLSNKNILSKSKDSSEDMNNHISNSSNDILNNIDISLPNDDLKLSLYQSGIECPICFLYYPKNLNYSKCCQQPICTECFVQIKRALPHFPHDDNEHNNEDDSEKDPHLLISEPANCPYCATPNFTISYSPIASRKTGINGVKQFYYKPPKANDDANLSNNTAKPVYLTSDTIRPDWEDKLNKERSRLQRRAANATAIHVSNQLISPGRSENNEIPSNLKELENQMIEQAIKLSLQDRKQNESGSRKKSSK
What is the function of this protein?
May negatively regulate the SNF1 kinase.
What are the official names of this protein?
Protein SIP5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y359_HAEIN
Sequence: MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYLAGIPLAIGAFFSGIFCSLGVGYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLTHILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYCFDPSHARVAGLSPKILHYGLLILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILSYHFDASTGACIILLQAAFFVIALAYSKIRIR
What is the function of this protein?
Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron.
What are the official names of this protein?
Probable iron transport system membrane protein HI_0359.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_DESOH
Sequence: MQKEKVNIKKNDKVKVVAGKDKGKIGKVLSVNREKNRLVVENINMIKRHTRPNVSNRQGGIIEREAPIDRSNVMLMCGKCVTPVRIKMKELEDGRKVRMCGKCKELID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.