PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_SHEB8
Sequence: MSLDLALDIQHATTCDWLPTDEQFALWVTTAIGNSMNEAELTIRIVDSRESQMLNSTYRGKDKPTNVLSFPFEAPPEIELPLLGDLVICAAVVENEAREQQKTLEAHWAHMVVHGCLHLLGYDHIEDEEAEEMESLETQLIEGLGFTDPYKEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_LACP7
Sequence: MISNEAFVLGCSAIGAGLAMIAGIGPGIGQGIAAGHGAAAVGRNPGARGNIMSTMLLGQAVAETTGLYGFAVAIILLFANPLLGKL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL20_SYNPW
Sequence: MARVKRGNVARKRRNKILRLARGFRGSNGTLFRTANQRVMKALCNAYRDRRRRKRDFRRLWIARINAAARLNGVSYSRLIGGLKQADVRINRKMLAQLAVADPSSFTTVVNATQG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS12_STRZT
Sequence: MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TF3C2_HUMAN
Sequence: MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSHRLLPTP
What is the function of this protein?
Required for RNA polymerase III-mediated transcription.  Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs.  May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.
What are the official names of this protein?
General transcription factor 3C polypeptide 2, TF3C-beta, Transcription factor IIIC 110 kDa subunit, TFIIIC 110 kDa subunit, TFIIIC110, Transcription factor IIIC subunit beta.
Protein: MINC_PHOPR
Sequence: MTKMAELKGSSFTLSALHLVDGDIKKATDYLKEKVNQAPNFFASAPVVIDITQAGREINFKQLKEDVKDAGMIPVGVSGCKDARMQNEAKSAGFAIMNAARQAKDMPVTVEPTRIIRTPVRSGQQIYAKNCDLVVMNHVSAGAEIIADGCIHVYGNLRGRAIAGASGQHQAQIFCQNIQSELISIAGNYWLSDKIKAEFWGKGVVISLAENNLNIEHLTL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: MAJE_PSESI
Sequence: ATPAYMSITGTKQGLITAGAFTADSVGNTYQEGFEDQVMVQGFDPAVIIPTGPVYGQ
What are the official names of this protein?
Major exported protein.
What is the protein family that this protein belongs to?
Belongs to the hcp1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHTC_ECOLI
Sequence: MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVETLAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR
What is the function of this protein?
Conducts the efflux of threonine.
What are the official names of this protein?
Threonine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FGF23_HUMAN
Sequence: MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRSAEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTGPEGCRPFAKFI
What is the function of this protein?
Regulator of phosphate homeostasis (PubMed:11062477).  Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (PubMed:11409890).  Up-regulates EGR1 expression in the presence of KL (By similarity).  Acts directly on the parathyroid to decrease PTH secretion (By similarity).  Regulator of vitamin-D metabolism (PubMed:15040831).  Negatively regulates osteoblast differentiation and matrix mineralization (PubMed:18282132).
What are the official names of this protein?
Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
Protein: DCDB_MYCBO
Sequence: MLLSDRDLRAEISSGRLGIDPFDDTLVQPSSIDVRLDCLFRVFNNTRYTHIDPAKQQDELTSLVQPVDGEPFVLHPGEFVLGSTLELFTLPDNLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCMLRLTSPSEHPYGSSRAGSKYQGQRGPTPSRSCQNFIRST
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CUTA_ECOSM
Sequence: MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_NEOVI
Sequence: MSMVYINIFLAFTLSFMGLLIYRSHLMSSLLCLEGMMLSLFVMMTITILINHLTLASMTPIILLVFAACEAALGLSLLVMISTTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNS10_BOVIN
Sequence: MKLTLVQIFFMMLLLLLGLGVGLGVGLQMAAAVLEESDQLLDEFLSSDSQDKAEATKEGLASRSTETLLVSNKEVVQPEDTIISEDEVGGDRMLRAEVLLHSNKDYLRSDVMDRECNALMALKVKSKDHTCIPQYIFIHEELDAVKAVCKSPAVACDLKGGKCHKSPRPFDLTFCKLSKSGQVIPHCNYVTFILEKYILMSCSDMKVQITS
What is the function of this protein?
Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility.  May be involved in sperm adhesion to the egg zona pellucida.  Does not have ribonuclease activity (By similarity).
What are the official names of this protein?
Inactive ribonuclease-like protein 10, Protein Train A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: MENB_STAAR
Sequence: MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: IRX2_HUMAN
Sequence: MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL
What are the official names of this protein?
Iroquois-class homeodomain protein IRX-2, Homeodomain protein IRXA2, Iroquois homeobox protein 2.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FENR1_LATSS
Sequence: MTAMTNIYETTIIGGGPAGLYAAFQAGLYGLNGQLLEGDQQFGGKVATYAERVIHDIGGMPNITGQDLIQNLTAQAAFYDTPLRTQTLVTDVKYLADQDYYQIDTPDDRYYSQTLILAMGGGVVRPKQLRLFEEQTFENVHYAPANPEDYRDQRVVLIGPGYNLMELAPHLLATAKSVVWLTTKRPFVDEAAEKAFLTAYPQIDYYCQPLASYQQVDQQVTSITLADQTQITFDQAVVSLGYRRSLQTLDQWQLSAEQIEERPDIWVIGNQIPDRAGISLLTSAFQDGITAVTEIVAQLKPTAKTPMVTTHNPVFQADTKAYWQERLR
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ENO_VIBPA
Sequence: MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAIEAVNGPIAEALVGKDAKDQAAIDAVMIELDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTAGQFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAATLKEAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAGLVEQFPIVSIEDGLDESDWDGFAHQTQLLGDKIQLVGDDLFVTNTKILAEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGERAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SUCC_PASMU
Sequence: MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGVKLVRNEAEVRAFADQWLGQRLVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQRVVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQGRELAFKLGLKGDQIKQFAHIFVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDPREALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAEAFKIILSDSAVKAVLVNIFGGIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREILANSGVNIIAANTLTDAAIQAVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: EGR4_RAT
Sequence: MLHLSDFSGPDALLSKPTEGCAHTSPELPRLPARDAPSAAAYPGGDFLSWALSTCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPSPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGAPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPASRLYPPGAYDAFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAVPQAQLSPLGLRGAATADFSKALVADLPGGSGVAAPSSPATSFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRTFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL
What is the function of this protein?
Transcriptional regulator.  Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG).  Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
What are the official names of this protein?
Early growth response protein 4, EGR-4, Early response protein NGFI-C, Nerve growth factor-induced protein C, NGFI-C.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VAC7_SCHPO
Sequence: MSEPKPMQMSVETETVLNVSQVQIPSSCDRKASLETLKTKKNAQKKKKISLPNVMTSKAAMFAARVASAVDQDPNDEESENFVYENLIPTNDDELHSPSASIHSFQTYNLPLEMLPTINHVPYYGSAGTNALNGGPLSNSRKLIPKRSAKFSSMVGSSDTRCNSPTTARGLATSPLQINPTTSKSPLLNKKLSSTSQEPFRTSRRSGQESGDVTTKMLRNLLHKRLWISFFFACFVVLSLVYFHYAVQPLL
What is the function of this protein?
Component of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Directly involved in vacuolar membrane scission.  Required for normal vacuole acidification, inheritance and morphology (By similarity).
What are the official names of this protein?
Vacuolar segregation protein 7.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Vacuole membrane; Single- pass type II membrane protein.
Protein: DEFB1_HYLLA
Sequence: MRTSYLLLFTLCLLLSEMASGDNFLTGLGHRSDHYNCVRSGGQCLYSACPIYTKIQGTCYQGKAKCCK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Beta-defensin 1, BD-1, Defensin, beta 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: FOLD_ALKMQ
Sequence: MGEIIKGKPVADKISEDLIQEIEGLKGKGIQPKLAIVRVGANSSDLAYEKGALGRSKKVGVETEVHELPEDITQDDFIKELKKLNEDKAVNGILIFRPLPEQLDESVIKYVIAPEKDIDCLSPINVGKMTEGDKTGFPPCTPTAVVEILKFYGVELQGKDCAIIGASMVVGKPAALLLLNENATISVCHIFTKDSAKIASQADVVVVGVGVPRLVKENWIANGAVVIDVGINVDKEGNMCGDVDFDGVKDKVSMITPVPGGVGSVTTSILAKHVVKACKQQNNL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RHO_ALLVD
Sequence: MNLTELKKMPVPNLVALAQSMDIEGVGRSRKQDLIFAILKAQAKKGEDIYGDGVLEILSDGFGFLRSADASYLAGPDDIYVSPSQIRRFALRTGDTISGKIRPPKDGERYFALLKVNDINFDRPENAKSKILFENFTPLFAQKRLTLEIGNGSTEDITARTIDLVAPIGKGQRGLIVSPPKAGKTMMLQNIAQSIGHNHPDCYLIVLLIDERPEEVTEMARSVRGEVISSTFDEPATRHVQVAEMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMEIHMDRRIAEKRIFPAININRSGTRREELLMGQAELQKMWILRKILHPMDELAAMEFLHDKLKATKTNDEFFSSMKG
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: PTOV1_DROME
Sequence: MEPVPEEARGVGDDEGELDCLTHMIGALLLQKEPENPENGDSKETIWSGELEWEDAQILDQPKTLHTVQCKICSMVKEGQPEINTENWPNKLKTQLIPKKVLGKIGEQFLKDARMVVFRSSQGEVLNLLITAMSSGFAGCIHFPSNPNCNIKALILIYSRDHQALVGFIPNNEDSFSERLQEILQGAKRKPGVKTPKQPQPEEPPPVEEDAIINELLWTGSLNWSTQASLEEPSISHKLECSVYIAIKNGDPGISAEDWPTDMPMVLMPSIYLGQFAGAFIKDSKLIILRSTPGEEHDSLASSMSAGSCGCARFSSEVVCKVIMLLYSSPRNAFLGFIPRDQANFVKRLREVLDEHRQKARNKE
What are the official names of this protein?
Protein PTOV1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
Protein: TAL_PSELT
Sequence: MKIFLDTANLEEIKTAADWGVIDGVTTNPTLVAKENVPFEKRIKEICEIVKGPVSAEVTALNWNEMIEEAKKLAEIDKHVVIKIPMTKDGLKATKVLSEENIAVNMTLIFSSAQALLAMKAGARYVSPFVGRLDDISSDGMKLIEEIVQIIENYDFRAEIIVASVRHPMHIVHAALIGADIVTVPFKVLQSMFNHPLTDIGIDRFMKDWKDYQNRTK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_SALDC
Sequence: MPSLSKEAALVHDALVARGLETPLRPPMDELDNETRKSLIAGHMTEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFAGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILTALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHP
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: IPNS_LYSLA
Sequence: MNRHADVPVIDISGLSGNDMDVKKDIAARIDRACRGSGFFYAANHGVDLAALQKFTTDWHMAMSPEEKWELAIRAYNPANPRNRNGYYMAVEGKKANESFCYLNPSFDADHATIKAGLPSHEVNIWPDEARHPGMRRFYEAYFSDVFDVAAVILRGFAIALGREESFFERHFSMDDTLSAVSLIRYPFLENYPPLKLGPDGEKLSFEHHQDVSLITVLYQTAIPNLQVETAEGYLDIPVSDEHFLVNCGTYMAHITNGYYPAPVHRVKYINAERLSIPFFANLSHASAIDPFAPPPYAPARGNPTVSYGDYLQHGLLDLIRANGQT
What is the function of this protein?
Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
What are the official names of this protein?
Isopenicillin N synthase, IPNS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: GP5_PRRSL
Sequence: MRCSHKLGRFLTPHSCFWWLFLLCTGLSWSFADGNGDSSTYQYIYNLTICELNGTDWLSSHFGWAVETFVLYPVATHILSLGFLTTSHFFDALGLGAVSTAGFVGGRYVLCSVYGACAFAAFVCFVIRAAKNCMACRYARTRFTNFIVDDRGRVHRWKSPIVVEKLGKAEVDGNLVTIKHVVLEGVKAQPLTRTSAEQWEA
What is the function of this protein?
Major envelope protein present in abundant amounts in the virion envelope.  Mediates virion sialic acid-dependent attachment the sialoadhesin receptor SIGLEC1.  This attachment induces virion internalization into alveolar macrophages predominantly through clathrin-dependent endocytosis.
What are the official names of this protein?
Glycoprotein 5, Protein GP5, G(L).
What is the protein family that this protein belongs to?
Belongs to the arteriviridae GP5 protein family.
What are the subcellular locations of this protein?
Virion. Virion membrane; Multi-pass membrane protein.
Protein: MIAB_PARPJ
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLGAAEGLVKTDTPEDADVILFNTCSVREKAQEKVFSDLGRVRELKEANPNLIIGVGGCVASQEGAAIVSRAPYVDLVFGPQTLHRLPQMIDKRRESGRAQVDISFPEIEKFDHLPPARVDGPSAFVSIMEGCSKYCSYCVVPYTRGEEVSRPLDDVLTEIAGLADQGVREVTLLGQNVNAYRAGLTLGSTEIADFAQLIEYVADIPGIERIRYTTSHPKEFTQRLIDTYAKVPKLVSHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPDLSLSTDMIVGFPGETEEDFDKMMALVHEMKYDTSFSFIYSPRPGTPAANLHDDTPREVKLKRLQHLQATIEENVQRISDSMVGKIERILVERPARKDPNELAGRTENNRVVNFPAPIASHARLIGQMVDVKIVKAYPHSLRGELVLVHDDAPATTH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1779_PASMU
Sequence: MRNVKKALSRSVIASSIQGTTKTNGGHRSRHSSGIFLPQIYLSKGNGAYPHTFQKAEFVARATLRNKAHLRTNKGGFHPLVVVVEPLSRLLSVGKFLQNKPTEKIKMKTSQKSTALLAVRSRTPIVFAPAMEVTYA
What are the official names of this protein?
Uncharacterized protein PM1779.
Protein: IPI_BACSU
Sequence: MENQEVVLSIDAIQEPEQIKFNMSLKNQSERAIEFQFSTGQKFELVVYDSEHKERYRYSKEKMFTQAFQNLTLESGETYDFSDVWKEVPEPGTYEVKVTFKGRAENLKQVQAVQQFEVK
What is the function of this protein?
Directly regulates the major intracellular proteinase (ISP-1) activity in vivo.  Inhibits ISP-1 in the early stages of sporulation.  It may be then inactivated by a membrane-bound proteinase.
What are the official names of this protein?
Intracellular proteinase inhibitor, BsuPI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_IDILO
Sequence: MKSVTSLGVFGNPIAHSLSPRIHALFAQTRQDSINYQRYLSTPGHFPRRVAEFFRHGGQGANVTLPFKQQAASLVTKLSDRARLAGAVNTLIPYGNGLLLGDNTDGEGLIIDLKNKGLNVSERSLAVFGAGGSARGIIPLLLEQKPRCLYLVNRTAKKAEMLKSQLETLGLVAANRIQVRSSASEIDEPIDLLINATSSSLNGQRLTLPPLLSENASGYDLMYADQPTVFMEQLTQAGCKNVSDGFGMLIEQAASSYQLWMGDERPDTAFVMAEMRTPS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.