PharMolix/UniProtQA huggingface dataset:
Protein: UBIA_PROST
Sequence: MEGSMALSKWHAYSRLMRIDRPIGSLLLLWPTYWALWIAAQSIPSLHILIVFTAGVFLMRAAGCVINDFADRHFDGHVERTKHRPLPSGDVTEKEAKILFASLVGLSFLLVLTLNSMTIWLSVAGLALAWIYPFVKRVSHLLQVVLGAAFGWSIPMGFSAVSESLPLVCWVLFLVNILWSVIYDTQYAMVDRNDDLKIGVKSTAILFGQYDKLIIGILQIVMIVLLVLVGSLADLGAVYYIALSLSALLFIYQQKLMVDRERAPCFKAFLNNNYVGLILFIGIFLSYL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AAEX_MUSP7
Sequence: MHSLPVMVLFGLSFPPIFFVLLVSLTLFFICIRLLHSSGIYEWVWHPALFNTSLFCCLFYLLFHLGV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_TRIV2
Sequence: MTTSPIPTQESSTSWYLLLQQLIDGESLSRSQAAELMQGWLSEAVPPELSGAILTALNFKGVSADELTGMAEVLQSQSKLGSGENSSQLPITNYQFPIIDTCGTGGDGSSTFNISTAVAFVAAAYGVPVAKHGNRSASSLTGSADVLEALGVNLGASSEKVQAALQEVGITFLFAPGWHPALKAVATLRRTLRIRTVFNLLGPLVNPLRPTGQVVGLFTPKLLTTVAQALDNLGKQKAIVLHGRERLDEAGLGDLTDLAVLSDGKLQLTTINPQEVGVTPAPIGALRGGDVQENAEILKAVLQGQGTQAQQDAVALNAALALQVAGAVPLLDHAKGVSVAKEILQTGTAWAKLEQLVHFLKS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RS3_MARN8
Sequence: MGHKVNPTGIRLGVIKEHNSVWYADKKDYAKNLLNDIQVREFLDKRLVKASVSKIVIERPAQNARITIHTARPGIVIGKKGEDVDRLRREVSDMMGVPVHINIEEVRKPDLDARLVAQNVAGQLERRVMFRRAMKRAVQNAMRQGAKGIKIQVGGRLGGAEIARSEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFKGEILGGMEQVRADKKASGKKGSK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SURE_ZYMMO
Sequence: MRILITNDDGIAAQGIKILEEIAHKISDDVTVVAPDKERSGMAHSLTLSLPSRLYKHDDRHYSVSGTPSDSVVMGIKEIMKDNPPDLVLSGINHGANLAEDVTYSGTVSAAMEGAIAGIRSIGLSQVYSPDFKNGALSFDTAVSWGEKVIRQLIDSTLPNRTFYNVNFPACENDDVKGIRVVAQGHRDYGRLNVEKGVDPRGKDWYWLALGEAISKDNLNGDLDLSYQNYVTVTPLAPNLTDVASLQPLTDILAK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN1A_STAES
Sequence: MPKRSFTKDDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVFKTDGTPFEGDPRANLKRVLRRMEDMGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDLAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKENAFFDPEGDLQLTDTAYQFTAGVLKNARGFTAVCNPIVNSYKRLVPGYEAPCYIAWSGKNRSPLVRVPTSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIENKLEVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENKSIKNALGNHIYNQFINSKSIEWDYYRTQVSEWEREQYIKQY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC73_YEAST
Sequence: MANSLDRLREHLKNGDKLVLKNNEGQSTDDITKATMVETLSSDGSTQDSFPLNEETEIEIDGSLVQLRIIVHCWMNKDSSAADYLADCQNKQLTNVSFLQRTDLINWLSGNTESSQYLKAPGQKGETSDKVDIENKTLAGELSTVKSTTSASLENDSEVSDPVVVETMKHERILVDHNSALRGAKPINFGYLIKDAELKLVQSIKGSLRGSKLPPGHKGAHGRISKTNGSSGGPRKDPIILIPSAASSILTVANIKQFLLESKYVNPRNLPSVPNGLVNIEKNFERISRPIRFIIVDNTRMFTKPEYWDRVVAIFTTGHTWQFNNYQWNSPQELFQRCKGYYFHFAGDSVPQHVQQWNVEKVELDKNKRFKDVEVVRYFWHSLEKELISRGYR
What is the function of this protein?
The PAF1 complex is a multifunctional complex.  Involved in transcription initiation via genetic interactions with TATA-binding proteins.  Involved in elongation.  It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II.  Also has a role in transcription-coupled histone modification.  Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B.  Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2.
What are the official names of this protein?
Cell division control protein 73, RNA polymerase-associated protein CDC73.
What is the protein family that this protein belongs to?
Belongs to the CDC73 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: SYE_RHOJR
Sequence: MTTSEVRVRFCPSPTGTPHVGLVRTALFNWAFARHNGGSFVFRIEDTDAARDSEESYQAILDALRWLGLNWDEGPEVGGPYEPYRQSQRRDLHLDVVAKLLAAGEAYESFSTPEEVEERHKAAGRDPKLGYDNFDRDLTPDQRQAFLDEGRKPVVRLRMPDHDLTWDDLVRGETTFKAGTVPDFALTRGNGIPLYTLVNPVDDALMKITHVLRGEDLLSSTPRQLALYEAMQRIGVADFTPRFGHLPFVMGQGNKKLSKRDPESNLFIHRDRGFVPEGLLNYLALLGWGISDDHDVFSLDEMVAAFDISKVNSNPARFDQKKADAINAEHIRLLEPADFAARLRAFLTLHGHLGETVDESVFATAAELVQTRIVVLSDAWDLLKFLFVDEADFAIDPAAAAKNLGADSAPVLDAALASLDAVEAWDAASLEEALKTALVDELGLKPRKAFAPVRVAVTGSHISPPLYESMELLGRDVSLSRLRSARAGVAG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_HAES1
Sequence: MTIKILPPQLANQIAAGEVVERPASVVKELIENSLDAGATHIQIEIENGGANLIRIRDNGIGIAKDELHLALARHATSKIASLDDLEMILSLGFRGEALASISSVSRLTLTSRTAQQNEAWQVYAQGRDMETSITPASHPIGTTVEVANLFFNTPARRKFLRTDKTEFAHIDEVIRRIALAKPQVAFTLTHNNKLIHRYKSAVTNEQKIKRIATICGNDFMQNALHIDWKHNDLHLSGWVIQPQFARHQNDLNYCYINGRMVRDKVITHAIRQAYSEYLNNEQYPAFVLFIDLNPNEVDVNVHPTKHEVRFHQARLIHDFIYQGMTNALTSEQTNIPIQSEQSNPTKVAEPQGIWNLTTHNKGNRATAGKNIFAQQPKDYDKKSSQFKPHFTANYSEVTPKKAVQKAYAELLVTHEEKTIASSTLPHQFTHNATYISEQKNVLHALALIENKALLLQQNQQYFLLSIQALQHFNIRLQLQQSNIAQQTLLIPILLRLNKQQYQSWQQQALFFQQSGFDFTENSAQHRITLNRLPICLRTQNIQKIILHLLDQPHEKYTIFLTALCSQLEFPSLSTFSEAVNLLTKTEQQFSTQHQPEFQSLLVKIEWDHYLDKLQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: YCF42_NEOYE
Sequence: MISGPNCLRVGQLAPDFSATAVYDQEFKTLKLSDLKNKYIVLFFYPLDFTFVCPTEITAFSDKYNAFSELNTEVLGVSVDSEYSHLAWLQTDRESGGLGDLSYPLVSDLKKEISAAYNVLNSDGVALRGLFIIDPKGIIQYSTINNLEFGRSVEETLRVLQAIQYVQSHPDEVCPANWKPGDKTMNPDPIKSKNYFAAA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Putative peroxiredoxin ycf42, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDHJ_PARMW
Sequence: MSETSKIPPASTEDTSAVVAPAAGPVSQWLQQQGFEHQALEPDHVGIEQIGVDAAVLPIIAAALKSNGFDYLQCHGGYDEGPGERLVCFYHLLAMAEQLEAMASDPAAQLREVRLKVFLSREGTPVLPSIYGLFRGADWQERETFDMYGIQFDGHPHPKRLLMPEDWKGWPLRKDYVQPDFYEMQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KVD42_HUMAN
Sequence: MDMRVPAQLLGLLLLWLPGVRFDIQMTQSPSFLSASVGDRVSIICWASEGISSNLAWYLQKPGKSPKLFLYDAKDLHPGVSSRFSGRGSGTDFTLTIISLKPEDFAAYYCKQDFSYP
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Probable non-functional immunoglobulin kappa variable 1D-42.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ACBD5_HUMAN
Sequence: MFQFHAGSWESWCCCCLIPADRPWDRGQHWQLEMADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSSDITSVRLEKISKCLEDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVLQRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYLYYQRRRRKLN
What is the function of this protein?
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy.  Binds medium- and long-chain acyl-CoA esters.
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG37 family.
Protein: HIBCH_YEAST
Sequence: MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQIALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKKEQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTNDDTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:14566057, PubMed:25609543, PubMed:28154081).  mS47 has enzymatic activity in vitro, and is able to catalyze the specific hydrolysis of 3-hydroxyisobutyryl-CoA (HIBYL-CoA).  However, because the turnover rate of mS47/EHD3 is only a fraction of that of the homologous mammalian enzyme, the physiological function of this activity remains unclear (PubMed:12697341).  Has an indirect role in endocytic membrane trafficking (PubMed:11378903).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H, Mitochondrial small ribosomal subunit protein mS47.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. Mitochondrion-specific ribosomal protein mS47 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: Y906_TREDE
Sequence: MINLNDVSYKYNDTAAQAIQHISLSVKKGELVVITGKSGCGKTTLFRCVNGLCPRFYEGEITGSLTLNGKVLSSMRICDISNIAASVFQNPESQFFTTDVLSDLVYPCENCGIEKEEIQERLHRVTKLLSLEPLLNRKLSELSGGEKQKIAIASVLMLDTRVVLMDEPSSNLDYQSVELLTQILAQLKSKGYTLLIIEHRLHYLAELCDRLIVMENGSIVREYEKDLLCTIGNDEFHKQGLRGLHLFQNNSNTLITPQRQHTDKRLLTLHDIHFGYRKNTEVLKGIHLSIYPGDKIALIGKNGCGKTTLGKILCGLKKEQSGTVLLDGRSFPARVRSKTAGYVMQNVDFQLFGCSVYDDLLLGNEALPDKENRIQTVLEKLSLSALQEQHPTTLSMGQKQRLVVAASFLQNKRLTIFDEPTSGLDYGSMQNVCALIDSITGKTNASVIITHDYEFILNTCNRAVLLEDGQIKEDFQLNGSMQLEYIFKERL
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein TDE_0906.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPB_ACIC1
Sequence: MTATIDNTQSQATTGGVGRVARVIGPVVDVEFAADELPEIYNALTVDVDFATASEQVEGETKRTLTLEVAQHIGDNMVRAISLQPTDGLVRGALVRDTGAPISVPVGDVTKGHVFNVLGQTLDVPRIEVTERWPIHRPAPAFDQLEAKTEMLETGIKVIDLLTPYVRGGKIGLFGGAGVGKTVLIQEMIHRVAKNFGGVSVFAGVGERTREGNDLFLEMTESGVINDTVLVFGQMDEPPGCRLRVGLAALTMAEYFRDVKRQDVLLFIDNIFRFVQAGSEVSTLLGRMPSAVGYQPTLADEMGALQERITSTRGHSITSVQAIYVPADDITDPAPHTTFTHLDATTVLSRPISEKGIYPAVDPLDSTSRILDPQFIGEEHFRVANQVKQILQRYKDLQDIIAILGIDELSEEDKVIVGRARRIERFLSQNMFVAEAFTGQPGSFVPLDETIDAFRRLCEGELDHLPEQAFFMCGGLDDVQAKAKRLAERS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MNMA_BEII9
Sequence: MELGSSDVTSSGLDHAGLNSLGLPKPPALTRVVVAMSGGVDSSVVAALLKREGYEVIGVTLQLYDHGEAVHRKGACCAGQDIQDARQVADQLGIPHYVLDYEERFRRKVIDPFAQSYATGETPIPCVSCNSEIKFADLFETAQHLGADVLATGHYVSSKAEADGGRALYRSLDSSRDQSYFLFATTNAQLELLRFPLGDLAKPDVRQMARQLGLVVADKADSQDICFVPSGKYSDVIERLSPGAVVPGEILHVDGRVLGRHSGVIHYTIGQRRGLGLGAVGAGAGEPLYVIRLDAAKAQVIVGPRQALATRRVHLRGVNWIGPGSLQDMDEHGLEIFVQVRSTRAPIPGFLHAHESEIWVDFALDEDGVSPGQACVFYENDQPRARVLGGGFISATESALQMREMFPKPPNEDLLDTNESSDLVSPKRSAC
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_HELPY
Sequence: MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRSPHVNKDSREQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSMETK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YNFB_ECO27
Sequence: MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQRAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVIIP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: MURE_YERPE
Sequence: MRDLFAPWGLDVPERALREMTLDSRIAAAGDLFVAVVGHQTDGRRYIPQAIAQGVAAIVAEADGVAPDVSVAEIHGVPVIYLRNLNQHLSTLAGQFYHQPGAALRLVGVTGTNGKTTTTQLLAQWSQALGETSAVMGTVGNGLLGQVIPTENTTGSAVDIQHLLRNLVDQGATFAAMEVSSHGLIQDRVAALSFAAVVFTNLSRDHLDYHGNMTSYEAAKWLLFSTHQSEHKIINADDDVGRRWLSQLPQAVAVSMAGNVPKGWNGPWLSANKVIYHDNGASIAFDSSWGEGELESRLMGAFNVSNLLVALATLLVQGYPMAQLLAAAPHLQPVCGRMEVFNAPGKPTVVVDYAHTPDALEKALAAARLHCTGKLWCVFGCGGDRDKGKRPLMGGIAEQLADCVVVTDDNPRSEEPQAIVADILSGLLDAGRVQAIHGRAEAVTSAIMQAKEDDVVLIAGKGHEDYQLVGNRRLDYSDRVTVARLLGGQA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_SALA4
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDGRLAKAQIEEAMGGLPVEAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFFTQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRALKEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGATLLLSGSFLLVNRPEWGLMPGWLMVGGVVVWLVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTPR_CAEEL
Sequence: MRINRWIWWATVILLYLRTGLAADFFRSSEENDRKSSDDLDNFNSTKIEPDKPKTAKELGVKSCESNQDCVHDGVCHRGNDGHGICMCPRSCPAITPKQCGYNYRTPSTCLLMDADYRSKYDVKEPTCYSRKCVCPPQFDDVHVTANQKPLRLNSTLLPTKCDKRDLAVVARAHPSTSVSKGIDVTLFCCINVDPEGFIDVASVFFIQNGTIMREATSHPFAPRNGLARRVHEKYSCWELEIKNAQTSDSGSYMCRVTASASDLDVTDTMQFEVKAPRQIKNLTVNPSERDAIVTWESEGGEDMAIDLRLVRRTDTRGQVVFSKDNLTSPVSIKDLRAATPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSALSCEVEWKSPAEPNGRITKYFVSVRGAMRKSDGSLTPDDLPAAVEVDKRCANWDGDENTSKHNGINPIDFANEFYSCKFGPLKPNRNYTVTVWAENSAGRSLPAVFHKNCVTNYAQPDMVETPQPLLSNNHSTFSLTFPQPPDDINGPISCYYIAIVPLPANVSLDILPKSEEIVMHSFSKVFTNNLLPSSAEEKRFFAYIAESYVQLPEETTIGDGVRVSDLKACNVQYLSRYSSEDLALRRGLKYTGFLIVRVDKEEELNRKDVRNGADPNIFRNLIDKSVSPTSRTRTASPMSRHLRQLHLSGPAYGYSAYFKPILLDTESSSSGFGIFMKIILPFLLFLAFATGVTMFFVNRKGHMLSTWCPLFTKMTSKDVVERTLLKQTFGAIPVDDLPTEYVVRHRDTDFLFAQEYESLPHFQLDTVASNRKENAIKNRYNDIRAFDDTRVKLKKINGDDYSDYINANFIKSWKEKKLFIAAQAPVDATIGDFWRMVWEQESYLIVMVANLTEKNRQQCAKYWPDEQITRYGDIIVEPASFSFHSDYAIRAFDIAHIGECGPDVIPNGNGVEYANVPIVKGQFANNSRRILQYHFTNWNDYKAPECSTGLLRFMYRLRELPQFNNSPVVIHCSAGVGRTGTFISIDSMLDQCLAEDKANIFEFVCNLRRQRNLMVQSLEQYVFIYKALAEWHMYGDTDEDVRDFEDHYQRLCASNRDRAVSFNQQSSTNGSISPRVAIVSSRESMTTSNGETGLEEEFKKLERNLTTPLSSNFAAKDENLLKNRYEAAVPFDKYRVILPPTIGHADSSYINASHIKGYFFDYIAAQDPVSEGTAFDFWRMIADQNVTTVVMLSDETDWSDVEKYWPIDGSGTECHFGSERNSVNVTCVSEEHHQDFIIRNLSYSMKDNESMPANQEVVQYSYTGWPSDSIVPKSANSLMNLIEMVLQRQSSLMGSQAPIVVHCRNGSSESGIFICISLLWLRQKAEQRIDVFQTVKGLQSHRPMMFTRFEQYSFCYRALADYISKTYR
What is the function of this protein?
Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity (PubMed:9585503).  Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle (PubMed:9585503).  During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles (PubMed:16495308).  Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine (PubMed:15990870).  Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord (PubMed:15990870).  Promotes the outgrowth of the quaternary dendritic branches of the PVD sensory neurons (PubMed:26968353).  In parallel to the sax-7/mnr-1 pathway, also controls the extension of the PVD primary branches (PubMed:26968353).  Acts in the netrin/DCC pathway to mediate the formation of synapses between the AVA interneurons and the PHB sensory neurons (PubMed:29742100).  Also required for the formation of synapses between the AVA interneurons and the VA10 motor neurons (PubMed:29742100).
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Synapse.