PharMolix/UniProtQA huggingface dataset:
Protein: RS18_ALKMQ
Sequence: MVNRRRKKMKKKVCTFCADKSSKIDYKEVHKLKKYVTERGKILPRRISGNCAIHQRDITQAIKRSRHIALLPYTID
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GLYA_PROMT
Sequence: MKCDPSIAKLINNELSRQETHLELIASENFASKAVMEAQGSVLTNKYAEGLPNKRYYGGCEYVDGVEQLAIDRAKNLFGANWANVQPHSGAQANFAVFLSLLKPGDTIMGMDLSHGGHLTHGSPVNVSGKWFKTCHYEVDKKTEMLDMDAIRKKAIENQPKLIICGFSAYPRKIDFKAFRSIADEVNAYLLADIAHIAGLVASGLHPSPIPYCDVVTTTTHKTLRGPRGGLILSKDKEIGKKLDKAVFPGTQGGPLEHVIAAKAVAFKEASAPEFKIYSQKVISNAKVLSNQLQKRGISIVSKGTDNHIVLLDLRSIGMTGKVADQLVSDIKITANKNTVPFDPESPFVTSGLRLGSAALTTRGFNEQAFGDVGNVIADRLLNPNDEDIKEKSINKVSELCNKFPLYSENI
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_MARSD
Sequence: MKIAVIGAGAWGTTLANTLAKKGHNTHLWVREQELCDEITNTGYNSVFLPDFKLSPDLKCSSNPQQVMEGADYFLLVVPSQFLRSALADMKQYFPQNPAVVCASKGIELNTGAPMSQVVFESLEGLNPRFAHLSGPTFAYELSAELPTSIVLGCGDEKLAAEVQDIFSTPYLRIYTNPDYRGVELGGAIKNIMAIAAGMADGLKFGHNTRAALITRGIAEMSRLGEAMGAQASTFMGLSGMGDLVLTCTGDLSRNRQVGLKLGQGMKLNEILKMRMVAEGVKTTESVYFLAKKLGVELPITEQVYKILYEDKDPATAVCDLMNRDLKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_MYCA1
Sequence: MARYTGPVTRKSRRLRTDLVGGDQAFEKRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRRYYEEAVRQPGKTGEELLRILESRLDNVVYRAGLARTRRMARQLVTHGHFTVNGVRVDVPSYRVSQYDIIDVREQSLNSVPFQIARETAGDRPVPSWLQVVGERQRILIHQLPERAQIDVPLTEQLIVEFYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YSO1_CAEEL
Sequence: MKNYFYCYPKSKIQMISSFEPPSSSSSSSDEDSDDEYREEDGNSERSNSKVCIEEVEEVEKEEIASRKRKRGKTKDEFHPCPFCEKKFRYPNKLREHIKIHDSNRYQCLECSTITKFGTYGELRAHHKLHHSKASHKCPQCSYTNEKPAFIRRHFEQNHVDGIPCTITGCCIKVAKNRLKAHIKEYHTSIPLSTEQTRSKLSFNKCPLCEYKPDVSDDDPEQQQKDLEDHVQRIHEEREPALCTLGCGVYLGSGSVSEHLSTCSSLIQNIPSSSQSTPALQNDEWNDANTETTLSTITGTSSQFERDSVSEVTNDLSENINDIDEEIEFGTTEPPNKIRKHSRSRVHGDFSCEICLKTFTLRDNLRKHVRVYHSENSQKVVKSTGPKHQEQYKCDRKSKDGDETTCGKTFRTEQALHDHFNVHDGIKPYSCHTCNQKFHARDRFAVHLSKYHQTSIKDLTARVATFGC
What are the official names of this protein?
Putative zinc finger protein F56D1.1.
What are the subcellular locations of this protein?
Nucleus.
Protein: VKT2_OXYSC
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPDFCELPADTGPCRVGFPSFYYNPDEKKCLEFIYGGCEGNANNFITKEECESTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor scutellin-2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNI_MOUSE
Sequence: MKFPGPLENQRLSSLLERAISREAQMWKVNVPKIPTNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLNCIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSARPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFKGSMLALAMVSLEMEKLIPDWLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSALPLNSVYVYRPLKHTLVTCDKGAFKLHPSSVSGPDFSKDNSKPEVPVRGPAAFHLHLPAASGCKQTSAKRKVEEMEVDDFYDGIKRLYNEDNGPENVGSVCGTDLSRQEGHASPCPPLQPVSVM
What are the official names of this protein?
Cyclin-I.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
Protein: CLPB_COXBU
Sequence: MRIDKFTTAFQTALADAQSLAVGRDHQFIEPAHVMKVLLEQTQGTVAPLLEQSKVNLSRLIDGVNKAIDSYPQVEGTGGEVHVSRELSKILTLMDKFAQQNKDQYISSEWFIPAALEAKGQLRDVLIEAGADKKAIEKNIMNLRKGERVTEQSAEDQRQALAKYTIDLTEKAETGKLDPVIGRDEEIRRTVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKQKRLLALDMGALIAGAKFRGEFEERLKAVLKDIAKEEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYRKYIEKDAALERRFQKVLVEEPSTEDAIAILRGLKERYEVHHGVEITDPAIIAAATLSQRYITDRNLPDKAIDLIDEAASQIRMEMDSKPVELDRLERRLIQLKIEREALKKETDEASKKRLSDLETEIKNVEKEYSDLEEVWKSEKASLHGTQQIKEELEQARIELEAAGRAGDLARMSELQYGIIPELDKKLKAASQKEEQFHDHKLLRSRVTEEEVAEVVSKWTHIPVSKMLEGEREKLLHMETELHKRVIGQDEAVNAVANAIRRSRAGLSDPNRPVGSFLFLGPTGVGKTELCKALAVFLFDTEDAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAIRRRPYSVILLDEIEKAHNDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIVMTSNLGSDLIREFSGENYDKMKDAVMEVVAQHFRPEFINRIDEAVVFHSLKKEQIRNIAIIQIDRIKKRLKEKDYQLTISDDALDYLSELGYDPVYGARPLKRVLQQQLENPLSQKILEGKFVPGSLINIEKKGEQLEFKEA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_GRABC
Sequence: MTRDVTLSLAQEFGLDAAEYQRVLDIMGRTPSFTELGIFSVMWSEHCSYKSSRHWLKQLPTKAPWVIHGPGENAGVVDIGDGLAAIFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGSPDHPATKRIIDGVVRGIGGYGNCVGVPTVGGEVNFHPSYNGNPLVNAMTVGIAPKDRIFLSAAAGVGNPVIYVGSKTGRDGIHGATMASTEFGADSEEKRPTVQVGDPFTEKLLIEACLELMATDAIIAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQREEGMNAYEMMLSESQERMLMILRPDRQDVARAIFEKWELDFAVIGHLTDTGHIVVKHQGVVEADIPLDPLAEQAPLYQRPTVETPKRAPLGEVADPVGIASALLTLIGSPDIASRRWIWDQYDSTVGGQTVRRPGAADAAVVRLDGTERALALTTDCTPRYCFADPEVGGAQAVAETWRNLTAVGAHPLAITDNMNFGNPQKPEIMGQFAAAIRGMREACLTLDFPVVSGNVSLYNETEGTGILPTPAIGGLGVLDNAETATGLSLRPGLDLVLIGTGGTTLGQSLWLREIAGREDGPPPAVDLAAERRHGDLVRSLIHQGKVAACHDLSDGGLLVAIAEMAIAGHTGAVLSGEGDHVFWYGEDQARYIIATTYSAAVLDAAKAANVPASLIGRAEGTDLQVPGCTPISVATLRERHEAFLPALMAQR
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRE5_HUMAN
Sequence: MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
What is the function of this protein?
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation.  Plays an essential role in leukocyte migration.
What are the official names of this protein?
Adhesion G protein-coupled receptor E5, Leukocyte antigen CD97.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space.
Protein: SFSA_PSEP1
Sequence: MRFSPSLEQGRLLRRYKRFLADIELASGEQMTIHCPNTGSMLNCMREGGQVWFSRSNDPKRKLPGTWEISETPQGRLACVNTGRANALVEEALRAGTITELVGFTALKREVAYGEEGSRIDFRLEFEGAPAYVEVKSVTLGYPDTAVAAFPDAVTQRGAKHLRELAKLARQGVRAVQLYCVNLTGIDAVRPAEEIDTAYAQALRAAVADGVEVLAYGTRLDAEGIVIDRRLPVLLTP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: HCHA_STAAW
Sequence: MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSTLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y584_MYCTU
Sequence: MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
What are the official names of this protein?
Uncharacterized glycosidase Rv0584.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 92 family.
Protein: SECA_BORGP
Sequence: MLKAVLEPAIGSKSKRDLKDYLPTLRNINKLERWALLLADEDFSKETQKLKYELKSGNSLENILERAFTLSREAARRRLKERPYDVQIIAGLALHEGKIIEMKTGEGKTLSSVQAAYLNSLTGDGVIIVTVNDYLAERDSNWMKPVFDLLGVTVGVVLSNMDYERRKDQYAKDITYVTNNELGFDYLRDNMRYDLNEKCLRKFNYCIIDEIDSILIDEARTPLIISGPTEGNTNAYLEVNSLVSFLKECSKDSKSGDYPLEIDDLDGDYTIDEKAKRISFTAKGLNNLEQLLVSKGIISGSLYTDSNFNYVHYMTQALKAHLLFFKNREYIVGDSGVEIVDEFTGRVLTGRRYSDGLHQAIEAKEEVRVANENKTMATITFQNLFRMFDKISGMTGTADTEAKEFHKIYNLDVVVVPTNRLLARIDEEDTIYYTEEFKFHAITDEVYKTYKKGQPVLVGTASIEKSEILSAMFKNRGIKHEVLNAKNHSREAFIIAEAGAKHAVTIATNMAGRGTDIKLGGNIEHRVRKKIGTNVSLEEFQEAVKNERENYLKDYNEVKSLGGLYVIGSERHESRRIDNQLRGRSGRQGDPGRSRFYVSLEDDLMRLFAGDSLRSLMGKLGMATGEPITHSLLTKSLINAQKRVEDRNFEIRKHLLEYDDVITKQRDFIYAQRNSILEDTAIKDRILIALEEYLSFLLEGTKGGSVSSVFLNEINLIFAYMLESLGSIENINSLDLKAKLMQIARANLDEKENLIGRDLFNGFLRYEYLKNIDFKFQEHLANLDSLREAVYLRSYANKNPITEYKEEGFLIFSELIKDIKVSTIRRVLQLKLDSNSSDFKSVKKSKNVNSIHKELSGILINENKNVSNVQVVRSSPKIGRNEPCYCGSGKKYKNCHGKS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CAIE_SALPC
Sequence: MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQDLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: PILC_PSEAE
Sequence: MLVKAHLRKQGINPLKVRKKGISLLGAGKKVKPMDIALFTRQMATMMGAGVPLLQSFDIIGEGFDNPNMRKLVDEIKQEVSSGNSLANSLRKKPQYFDELYCNLVDAGEQSGALENLLDRVATYKEKTESLKAKIRKAMTYPIAVIIVALIVSAILLIKVVPQFQSVFQGFGAELPAFTQMVVNLSEFLQEWWLAVIVGVGAIGFTFKELHKRSKKFRDTLDRTILKLPIFGGIVYKSAVARYARTLSTTFAAGVPLVDALDSVSGATGNIVFKNAVSKIKQDVSTGMQLNFSMRTTSVFPNMAIQMTAIGEESGSLDEMLSKVASYYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIVAMYLPIFQLGNVVG
What is the function of this protein?
Essential inner membrane component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers.  Controls both pilus assembly and disassembly and plays an important role in PilB localization to the complex and ATPase activity.
What are the official names of this protein?
Type IV pilus assembly protein PilC.
What is the protein family that this protein belongs to?
Belongs to the GSP F family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS131_ORYSJ
Sequence: MGRMHSRGKGISSSAIPYKRTPPSWVKTAAADVEEMIMKAAKKGQMPSQIGVVLRDQHGIPLVKSVTGSKILRILKAHGLAPEIPEDLYFLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKRTKKLPPTWKYESTTASTLVA
What are the official names of this protein?
40S ribosomal protein S13-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NHAA_HAEDU
Sequence: MIEKIQKFLKLEAAGGILLLIAALLAMLCANSVFSPYYFEFLQTQVAVKLGAFSIDKPLLMWINDGFMAVFFILVGMEVKRELLEGSLSSYQKAIFPAFAAIGGMVVPALIYWFINRDYPEYQQGWAIPMATDIAFALGIVALLSKQVPATLKVFLLALAIIDDIGAIIVIALFFSNELSMLALIIASIAIMILITMNRYKVTGIIHYVIVGTILWASVLKSGVHATLAGVIIGFCIPLRGKKGETPLHDLEHTLAPWCAFAILPLFAFSNAGVSLAGMSLAKLTSPLPLGITLGLLIGKPVGVFSFCYLAVRAGLAKLPEGINFKQVFAIAVLCGIGFTMSVFIAGLSFGEEHPDETILALSRLGILIGTSIAAIVGYILLKKTTNKPLVQAG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUD_FRAAA
Sequence: MEAFTIHTGRAVPLRRSDVDTDQIIPSEWLKRIERTGFGAGLFSEWRADEGFVLNNPAYAEASILIAGPDFGTGSSREHAVWALQDYGFRAVISPRFADIFRGNALGNGLLPVQLPAETVETLQTAAEQDPSVEITVDLAAREVRGAGLVAPFELDDFTRWRLMEGLDDVGLTLRHEELITGFEATRPAWLPSAV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: AVL9_YEAST
Sequence: MDEHEEAVIFGICLVDFHHKRGPEIEYWYGLPEGTQSAELWPNLPFQALPDGSHSFEETFTYFTLLYDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQIKSDELVTKDKDVTRSTVQKAIVVISRQPIFGQIKDKLSIVTNAFFLQHDFGDRKIIQSLYENLKSIYTPASLVRNAENRLYIGLCLRKILHDFKRNALVLLKAIMLEKKIIVYGNDVEALCNLQFGLISLIPDLMSNLQDSGSPQLFQDISKLNVVDSFKSSNRESVLRFLGFPLPIFEKGGLFSPYTPLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTVDILDKTLNPVLQLSSHDKKWIESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFEDYLTGLLSSVKLSDYLDLHKENDQALKTIPEDMLNSNPVHLFNLNWVQSWKETQNFLIFNSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLATFHNLKRSSSNSSSNKNGHQSEEDIKDQESIESKKSVSQISVNPGKNTDKPAANLWNSWKEYFNKPKNTANEDVTESTEDLKNRSKTSNAIQKAMMGLGLHYKPDAETDQQSEEVGNSEDNEDDDTDEDSEDDDDDGGDDDDSEDDDDDDDGEGDENGDDGEGDENGDDGEGDENGDKEDSQDFSNGFTDVTNINTDHDKENEQNFEGNAENFNEDETVADKDIEGGPESNKNSDSKTDIYENDRNVEDSSKTRNTVKKSNEEGGANDAAIGNCVQDEEKL
What is the function of this protein?
Functions in the late secretory pathway.  Required for the generation of secretory vesicles as well as for actin polarization and polarized growth.
What are the official names of this protein?
Late secretory pathway protein AVL9, APL2 VPS1 synthetic lethal protein 9.
What is the protein family that this protein belongs to?
Belongs to the AVL9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_VIBC1
Sequence: MTAQNIDGTLISQTVRSEVAARVKARVEAGLRAPGLAVVLVGEDPASQVYVGSKRRACEEVGFVSKSFDLPATTSEEELLALIDELNNDAEIDGILVQLPLPAGIDATHVLERIHPEKDVDGFHPYNVGRLAQRIPKLRSCTPKGIITLLDRYNIELRGKHAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLEGHVRQADLVVVAVGKPNFIPGEWIKKGAVVVDVGINRLESGKLVGDVEYDKARENASFITPVPGGVGPMTVASLIENTMLACEQFHTKK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DEF_ENT38
Sequence: MAVLQVLHIPDERLRIVAEPVKEVNAEIQRIVDDMFDTMYAEEGIGLAATQVDIHKRIIVIDVSENREERLVLINPELLEQSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKSFELEADDLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRMRTRA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ZXDB_MOUSE
Sequence: MEIPRLLPARGTPQGAGGGGCPAGGGGVHRAPASLACQAPTRRLLLLRGAQDGGPGPRSAEAQRASRGLGPSLNRLAPRPDHRSSGGGRGGGAGGGGGGSGGGGGGGGGGGGGGGGGGSRGGSDDFFLLLLDPVGGDVETVGTEQAGAPVRREEAGAGPRPERRQSAGPPAGRPEPGPRCLSAVPAASPLPAAGPGPAAAAAAAAAAAFAGTITIHNQDLLLRFENGVLTLTTPPLPAWEPGVAPFPQPQPPPQPGALIAPQAAAAGFPPAAAAAAAAAAAGAQLGDCPELPPDLLLAEPAEPAACPAPPEEEAEAPAAAAAQSPRGPAGPGPGPGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLSGCGWTFTTSYKLKRHLQSHDKLRPFGCPVQGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLSTHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFACSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHEDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVGAWKSRCPVPTCNKLFTSKHSMKTHMTKRHNLSQDLLAQLEAANSLTPSSELTSPGQSDLSGAELVSLFSDVPGHGSAAVLDTALVNSGILTIDVASVNSSLAGSLPADNNSNNHSLGQAAEPRALRGAPSDLPQSLDTSLFFGTSVAGYQHSPLDMDDVSAGNVGLFGSLALKNSSLEPQALTPSNKLTVDTEALTPSSTLCENSVSELLTPAKAEWNVHPESDFFGHEEETQFGFSHPTGSHGSQKDTDLITVTGTPFLV
What is the function of this protein?
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
What are the official names of this protein?
Zinc finger X-linked protein ZXDB.
What is the protein family that this protein belongs to?
Belongs to the ZXD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GASP1_HUMAN
Sequence: MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
What is the function of this protein?
Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors.  Targets receptors for degradation in lysosomes via its interaction with BECN2.
What are the official names of this protein?
G-protein coupled receptor-associated sorting protein 1, GASP-1.
What is the protein family that this protein belongs to?
Belongs to the GPRASP family.
What are the subcellular locations of this protein?
Cytoplasm.