PharMolix/UniProtQA huggingface dataset:
Protein: PELF_ASPNG
Sequence: MTLLRHLLTATALLGASVQAAQGVTGSPFGFASGTTGGGDATPAAPSDISQLKTWLSDSTPRVILIDKEFNFLGSEGKCTNCECCKPASNTCGSSGQNAVKQNGSDWCGSYPTLTCTYDNAGIEGLEVASNKSIVGVGSSGVLRGKGLRLVNGVSNIIIQNIHITELNPEFIWGGDAITLDGTNNVWIDHVKINLIGRQMFVAGYEASHSVTISNSEFDGETSWSATCDGHHYWTVLGYGHNDKITFANNYIHHTSGRSPKLEFNSFWHAYNNYWYNNTGHAFDVGKNTRALIEGNVMVQVDTPLLADSNPGAVFAVNTSDVSTCTSTLGRTCVPNTLISSGTLSGSDSSVISSWPSGESDVTVMAASKVASYVKANAGIGKLGNGSGSSSTVGAAATSAVAKRADSDDAPFVPAYSEAGPGASAVPTQPSWSWRTVTNGPAPTGAPSDSPSAPQGLGAPVQASNKHHHQGHGRGY
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase F, PLF.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ITIH3_RABIT
Sequence: MASAQWLGLVLALLSSLAASGFPGSPFRLLGKRSLPEGAVNGIEIYSTKINCKVTSRFAHNVVTTRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGHVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPANIQIVNGYFVHFFAPQGLPVVPKNVVFVIDVSGSMYGRKLEQTKDALLKILEDMREEDHLNFILFSSDVTTWKEHLVQATPENLQEARAFVKSIQDQGSTNLNDGLLRGISMLNTAREEHRVPERSTSIVIMLTDGDANSGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLESLALENDGFARRIYEDSDANLQLHGFYEEVANPLLTSVEMEYPKNAILDLTQNSYQHFYDGSEIVVAGRLADEDMNSFKADVKGHGALNDLTFTEEVDLKETEAALKEREYIFGNYIERLWAYLTIEQLLEKRKNARGEEKENLTAQALDLSLKYHFVTPLTSMVVTKPEDNEDQTAIADKPGEEQAQAASQTSFSAYRTSYQPPLGSAASYQPPLGTPYYYVDGDPHFIIQVPEQDNAICFNIDEEPGTVLRLIQDPATGLTVNGQIIGDKKSSPDSATRKTYFGKLGIASAHMDLRIEVTTEKISLWNEVGRSTFSWLDTVTVTQDGLSMTINRKKNMVVSFGEGVTFVVILHQVWKNHPIHQDFLGFYVVDSHRMSAWTHGLLGQFFHPFDFKVSDVHPGSEPTKPDATMVVKNRQLTVTRGSQRDYRMDARAGTKVACWFVHNNGEGLIDGVHTDYIVPNLF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H3, ITI heavy chain H3, ITI-HC3, Inter-alpha-inhibitor heavy chain 3.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSY_CUCME
Sequence: MSLASSLVVSSNVELSPSSFGFLDSVRDGPQIPDSFRFSSRNRVPNLINKKQKWGNHSHSTELKYPILHESGYGSVIVASMVANPAGEIAVSAEQKVYNVVMKQAALVKRQLRTAGELDVKPDIVLPGTLSLLNEAYDRCGEVCAEYAKTFYLGTMLMTPERQKAIWAIYVWCRRTDELVDGPNASHITPTALDRWEARLEELFQGRPFDMLDAALADTVTKFPVDIQPFKDMIEGMRMDLRKSRYKNFDELYLYCYYVAGTVGLMSVPVMGIAPESQASTESVYNAALALGIANQAPPNILRDVGEDARRGRIYLPQDELAQAGLSDEDIFAGRVTDKWRNFMKNQIKRARMFFDEAEKGVLELNKASRWPVWASLLLYRQILDEIEANDYDNFTKRAYVSKAKKILALPMAYGRALLGPS
What is the function of this protein?
Catalyzes the reaction from prephytoene diphosphate to phytoene.
What are the official names of this protein?
Phytoene synthase, chloroplastic, MEL5.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHS5_YEAST
Sequence: MSSVDVLLTVGKLDASLALLTTQDHHVIEFPTVLLPENVKAGSIIKMQVSQNLEEEKKQRNHFKSIQAKILEKYGTHKPESPVLKIVNVTQTSCVLAWDPLKLGSAKLKSLILYRKGIRSMVIPNPFKVTTTKISGLSVDTPYEFQLKLITTSGTLWSEKVILRTHKMTDMSGITVCLGPLDPLKEISDLQISQCLSHIGARPLQRHVAIDTTHFVCNDLDNEESNEELIRAKHNNIPIVRPEWVRACEVEKRIVGVRGFYLDADQSILKNYTFPPVNEEELSYSKENEPVAEVADENKMPEDTTDVEQVASPNDNESNPSEAKEQGEKSGHETAPVSPVEDPLHASTALENETTIETVNPSVRSLKSEPVGTPNIEENKADSSAEAVVEEPNEAVAESSPNEEATGQKSEDTDTHSNEQADNGFVQTEEVAENNITTESAGENNEPADDAAMEFGRPEAEIETPEVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNEFTTDIASPRHQEEDIELEAEPKDATESVAVEPSNEDVKPEEKGSEAEDDINNVSKEAASGESTTHQKTEASASLESSAVTEEQETTEAEVNTDDVLSTKEAKKNTGNSNSNKKKNKKNKKKGKKK
What is the function of this protein?
Component of the CHS5/6 complex which mediates export of specific cargo proteins, including chitin synthase CHS3.  Also involved in targeting FUS1 to sites of polarized growth.
What are the official names of this protein?
Chitin biosynthesis protein CHS5, Protein CAL3.
What is the protein family that this protein belongs to?
Belongs to the CHS5 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Trans-Golgi network location requires interaction with myristoylated GTP-bound ARF1 for the recruitment to the membranes.
Protein: VG23_ALHV1
Sequence: MEQGLKISTPNAKLVRGAVLLPSDKYVFHLIQSRTLCMALSMPGEYLPAPVLFDRFEGGSSGECSLHSRQNVCLYLVRILLSKHPYVLNSQLLVGYQHRQEAVVLYKQLLVKTKDFGISEIKLPCSIVVGPNPMSAEGTVQAERELPSCELVITSEFKTVWINESANQEKEFSPHDAISIPLAPGTPSKPIIKQPPFLPISKETAILHAQLFYAAGAGFPPIHNCPASAFTTLAVMCKSHNSINLVPELEIKPRQLLLLKHVLLTRMGLENCLQDFIQAYAERLPPLADEQVKYFEKVLGTAKDRAEDIIFILNSVGATSFTNRICSSNTDPMLTKAMQKYFLMFPPADPINALPFAVDIISIICQGANFNTVVLFVQRYIKIQERAAKTNQIKMFALLSI
What are the official names of this protein?
Uncharacterized gene 23 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BTRF1 family.
Protein: RPO2_SACSH
Sequence: MNELSSNLSIDERWKVIEAYFKSKGLVRQHLDSYNDFVRNKLQEIIDEQGEIPTEIPGLKVRLGKIRIGKPRVRESDRGEREISPMEARLRNLTYAAPLWLTMIPVENNIEAEPEEVYIGDLPIMLKSAIDPISQYTLDKLIEIGEDPKDPGGYFIVNGSERVIVTQEDLAPNRVLVDTGKTGSNITHTAKIISSTAGYRVPVTIERLKDGTFHVSFPAVPGKIPFVILMRALGILTDRDIVYAVSLDPEIQNELFPSLEQASSIANVDDALDFIGSRVAIGQKRENRIEKAQQIIDKYFLPHLGTSADDRRKKAYYLAYAISKVIELYLGRREPDDKDHYANKRLRLAGDLFASLFRVAFKAFVKDLTYQLEKSKVRGRKLALKALVRPDIVTERIRHALATGNWVGGRTGVSQLLDRTNWLSMLSHLRRVISSLARGQPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALMAQIAVGINEKIVEKTLYEMGVVPVEEVIRRVTEGGEDQNEYLKWSKVILNGRLVGYYRDGEELAKKIRERRRKGEISDEVNVGHIVTDFINEVHVNCDSGRVRRPLIIVSNGNPLVTREDIEKLDSGSITFDDLVRQGKIEYLDAEEEENAYVALEPSDLTPEHTHLEIWSPAILGITASIIPYPEHNQSPRNTYQSAMAKQALGLYAANYQLRTDTRAHLLHYPQRPLVQTRALDIIGYTNRPAGNNAILAVISFTGYNMEDSIIMNRSSVERGMYRSTFFRLYSTEEVKYPGGQEDKIVMPEPGVRGYKGKEYYRLLEDNGVVSPEVEVKGGDVLIGKVSPPRFLQEFKELSPEQAKRDTSIVTRHGEMGIVDLVLITETAEGNKLVKVRVRDLRIPSIGDKFASRHGQKGVIGMLIPQVDMPYTVKGVVPDVILNPHALPSRMTLGQIMEGIAGKYAALSGNIVDATPFYKTPIEQLQNEILKYGYLPDATEVTYDGRTGQKIKSRIYFGVVYYQKLHHMVADKIHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLLKDRLLDNSDRTTIYVCDQCGYIGWYDKNKNKYVCPIHGDKSNLFPVTVSYAFKLLIQELMSMIISPRLILEDRVGLSGGKGNE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (Probable).  This subunit is involved in DNA promoter recognition (PubMed:22848102).
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo2, DNA-directed RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_BIFLO
Sequence: MNLAYIPSPTFSKFEIGPFTIHMYAICILIGICVAVWILATRWKRYGGTFDQILDTTLVTVPCALVGARLYHCITTPADYFPPTGNLVNILKVWEGGMAIFGGISVGTLVAFLWCRHKHYPFAIFADAIAPALPVAQAIGRLGNWFNQELYGWPTTLPWGLKLNDADAIGKSEICYSGAQCPDYRTTLFHPTFLYEMIWNLIGAALIIYLGHKLADRLKAGQQFAMYLMWYGLGRTWIENVRINYSTVILGLRTNVWTAIIVFVLGCILFVVLYQYGPDPKAQARGLAAVTADELERQSIEEEQLRQKKQTNRTK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UB222_WSSVS
Sequence: MFTHLTRAFRKMNNLVNRSFIDVHRVVAELSYPEFEEDVKNPESSIYRTPISLFQNKDIVTIVGDYILSPKTDSFQVLYPIKKVIEHFPVIFHCTHNNAPLWVHLLDERHHRLLQSLLTYEIVNAKYRGIVVIPYYRRPINYQTGKSLLMSKLASVKVLDILMRCGSYKFISLMCMINKKNNTNFLHCCASKWGEVGSKMMLHIAEMFFANPTTSQHLSDASSFPDAAAEDDKGKTPAHLAIQEDNADALLFLISLYGAPWFQDNNSYMKSALELKSNKCVKVLSFAADKYEILPNINNNQLEPDTMCGVCATSVEEDENEGKTTSLSWYQMNCKHYIHCECLMGMCAAAGNVQCPMCREDVGDEVLERCPPTIFRWLKLAERSEHNRVLFEAKKQEFYKQMEAMKPPRVVVPPRRTFLTPARRGERAIRIAREIATNAIAEATAQGDVNSYFPVLIDGSGEEYEEEGEEFFNSEEEALAFGRPFLEDEEEARQIQMRQFAELSRRGVSVNIINNDNPHRHISTVNIVQPVYGVEKSPAASFIYNMLKNDVFESIRSRDTRVGGERVPVMNLSNDKRALFHAASSMLCDFATETNSQIVGLDFQAVYDPHHISNYIETFGSPLHAYPGAVTFLDGAQDYYAESIRYDNDIVSFSEMASELHITEALDVFEGSLLSPLFKKIRTGKSYSNWNDHLRRRNYARDIAEEFVRVCENSLASREHPPVHVHPFRDGAIPILIEYIVDFIHHCITWSMQVNALHCMRKYIEHENTNVHLLNLRPTDERVEVLRVSQLRWSRLFNEQYNTRMSLSTKRLSLMKIFNHDLGVSKFGVYKLLDIIEMYCFTLI
What is the function of this protein?
Probable E3 ubiquitin-protein ligase which accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2E1/UBCH6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Mediates ubiquitination of host tumor-suppressor-like protein (TSL) targeting it for degradation.  Might function as an anti-apoptosis protein by counteracting TSL-induced apoptosis.
What are the official names of this protein?
RING finger containing E3 ubiquitin-protein ligase WSV222, RING-type E3 ubiquitin transferase WSV222.
Protein: SPEE_SHEON
Sequence: MHESQLTTSAAKPSRLGWFDDVLLLGIMAVLAGCGLIYEYLLSHYAGRILGALEAAIYTMIGLMIVSMGLGAFAARKIKDAFTGFVVLELTVALCGSLAILITAAVIGFGQQLPMLIASTLGLPPDQLPEGGMIGTLQKLSEYLPYFWGVLLGLMIGMEIPLIARVRQSLSDEHLLHNAGTIYGADYIGAGIGAAIWVGFMLAIDIQLAAALTASFNLLAGFVFIWRFWQKIQRPKLLLAAHLVVTGVLLLLAIQGPSWEQQFNNLLYKDKVVYAKATRFQQLTFTERLRGNGLSPVYALYINGRLQFSSSDEHIYHAFLVHPTLAASARHNKVLIIGGGDGLGLKQVLRWEPEQVTLLDLDAALVQLFKSPDPDMPERLSQALLSLNGNAFNDPRVTVIHDDAFNGVDKLIAKGDKYDAIIVDLPDPSHPDLNKLYSDYFYRKLKELISNDGALTVQSTSPYHAQKAFISVAKTLALAGFDVKQYHHNVPSFGEWGWSIATLDGKDAQHRLAQLTKLPIADDWLTLGLVKGAFEFPANFYQDATNIKPNELGSLQLYHYHQQAWSETQGLDLF
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AZOR3_BACC1
Sequence: MTKVLFITANPNSAEGSFGMAVGEAFIEAYKNEHPQDEVVTIDLFNTTVPAIDADVFAAWGKFAAGEGFEALTEAQQQKVAAMNTNLETFMHADRYVFVTPMWNFSYPPVVKAYLDNLAIAGKTFKYTENGPVGLLEGKKALHIQATGGVYSEGAYAAVDFGRNHLKTVLGFIGVNETEYIAVEGMNANPEKAQEIKEAAIANARELAKRF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 3, Azo-dye reductase 3, FMN-dependent NADH-azo compound oxidoreductase 3, FMN-dependent NADH-azoreductase 3.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: AROB_THEP3
Sequence: MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKKSRFDVSYEVIPAGETSKTMEMAQRLLEKAYDYGLLRDSSVIALGGGVVGDIAGFVAATYMRGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIIGAFHQPKMVYIDTAVLNTLDKREILGGLAEIIKYGIIWDFSLFEYIESNIYEILDLEEDKLRHIIKKSCEIKGKIVSLDEKEENLRSILNFGHTIGHAIEALTGYERYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQRTGLPTDYEDLHKEDIVEAIKLDKKSREAKINFVLLRGLGKAEVTTVKEEEILKVLK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SYNY3
Sequence: MNKTVLPTIDNLDHKWYVIDAEGQRLGRLATEVATILRGKNKPTFTPHMDTGDFVIIINAEKIEVTGRKREQKLYRRHSGRPGGMKEETFEKLQVRLPERIVESAVRGMLPKNSLGRKLFTKLKVYAGPSHPHAAQQPETLVINTIPAGAN
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RTCA_ECO7I
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGLPFTITGIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVTSFNTLQLGERGNIVRLRGEVLLAGVPRHVAEREIATLAASFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFGLVEADGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_THEPD
Sequence: MSTRPEEAGNIKVGSFIVIDGEPCKVVEVEKSKTGKHGSAKARIVGIGFFDGGKRSIVVPTDARVEVPIIKKFTAQVVAFVGDNVQLMNLEDYSTFEIPMPQEEEIKSKLSEGVEVEVWEVMGRHKIMRVRA
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INN1_SCHPO
Sequence: MSKNPLGTLVVRIWKAKNLPNKALVGKQSPYCVCRVGEVVKRTQTDKRSGQEPSWNAVLEFNIPSESYHIMKITVFHEGFRKHPHLIGDTVLSFEKAMKEELQSEWYELKNEFQFAGELSVQFKFIPTDPLYFDRASSKPVLQFPYSSVAALTPVPKKPSKPSKPRKKVPVSHPLPPTPPSREEHVSVPRESSLFTYEDDPLPSFPSPYMVDDYYTQDVFVSDNVNDYSYGVQNPTNPRLSVEDYDANHSSLPPVPPPHLILPTASSSQIFH
What is the function of this protein?
Involved in the ingression of the plasma membrane during cytokinesis, leading to the separation of the daughter cells.  Unlike its S. cerevisiae ortholog INN1, it does not play an essential role, probably because the actinomyosin ring is connected to the cell cortex by many more proteins.
What are the official names of this protein?
Ingression protein fic1, Cdc15-interacting C2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the INN1/fic1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the barrier septum and the cell tip.
Protein: AAC6_KLEPN
Sequence: MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-I, Aminoglycoside resistance protein.
Protein: NCAP_RABVB
Sequence: MDADKIVFKVKNQVVSLKPEIIVDQYEYKYPAIKDSRKPSITLGKAPDLNKAYKSILSGMNAAKLDPDDVCSYLAAAMQFFEGACPDDWVSYGIMIARRGDKITPNSLVDIRRTNVEGNWALTGGMELTRDPTVPEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFVKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREALLYFFHKNFEEEIRRMFEPGQETAIPHSYFIHFRSLGLSGKSPYSSNAIGHVFNLIHFVGCYMGQVRSLNATVIATCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQEYEAAELTKTEMALADDGTVNSDDEDYFSSETRSPEAVYTRIMMNGGRLKRSHIRRYVSVSSNHQARPNSFAEFLNKTYSSDS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TBPL2_RAT
Sequence: MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNALPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV
What is the function of this protein?
Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes.  The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).
What are the official names of this protein?
TATA box-binding protein-like 2, TBP-like 2, TATA box-binding protein-related factor 3, TBP-related factor 3.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Present in the cytoplasm during cytokinesis.
Protein: DUT_CALS4
Sequence: MSIVLKIKRTEDAKDLPLPAYMSEGAAGMDLYANVKGEVTINPGEVELIPTGIQIELPPNYEAQIRPRSGLALNYGITLLNTPGTVDSDYRGEIKLIVINLGKQPVTIKRGQRIAQMVINQVVRPKIIEVEELSETERMDRGFGHTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MURC_PSEPG
Sequence: MVESQKAMPQPKMGRIRRIHFVGIGGVGMCGIAEVLLNLGYEVSGSDLKASPVTERLESFGAEIFVGHRAENAATADVLVVSSAINPANPEVATALERRIPVVPRAEMLAELMRYRHGVAVAGTHGKTTTTSLLASVFAAGGLDPTFVIGGRLTAAGTNAQLGTSRYLIAEADESDASFLHLQPMVAVVTNIDADHMATYEGDFNKLKKTFVEFLHNLPFYGLAVMCLDDPVVREILPQVKRPTVTYGFSEEADIRAINVRQQGMQTHFTVLRRDCEPLEVSVNMPGNHNVLNALATIAIATDEGITDEAIIQGLSGFQGVGRRFQVYGELPVEGGSVMLVDDYGHHPTEVAAVIKAVRGGWPSRRLVIVYQPHRYSRTRDLYDDFVQVLGDANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGKLDPIYIERGAELAPLVKPLLRAGDILICQGAGDVGGLAPQLMKSPLFAGAKQEKSK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_CALFG
Sequence: MNWRSERIWIELITGSRKTSNFCWACILFLGSLGFLLVGTSSYLGRNLISLFPSQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGINRRIFLRFLMRDIQSIRMEVKGGLYSRRVLYMEIRGQGAIPLTRTDENFTPREIEQKAAELAYFLRVPIELK
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS15_PICTO
Sequence: MARMHTRKRGRSGSKRIEVRERPSWIQYSDDEIKEMIVKMRKQGMTKSMIGIRLRDQYAIPGTRPVLHMKLGQVLKENNLESDVPEDLQALIERYKRAMKHLSLNKHDMNNKRKAQLIMSKMLRLIRYYKRTSRLPQDWSLERVLQ
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YGK3_YEAST
Sequence: MLKVNNVFGSNPNRMTKLEDEHYFIDDIVSIKNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRGSSMPVHLPDLFNFSASEKRALGEYYNLIVPSLD
What is the function of this protein?
Required for heat stress-instigated phosphorylation of BCY1 which is involved in cell wall integrity signaling.  Regulates activity of MSN2, a transcription factor that binds to the stress-response element (STRE).  Probably promotes formation of a complex between MSN2 and DNA.  Regulates the stability of ROG1.
What are the official names of this protein?
Glycogen synthase kinase-3 homolog YGK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: DNLJ_RICPR
Sequence: MQNIDLISEQEAKKLLKELADKIAMYNHAYYIEDNPLVSDSEYDQLFNINLKLENTFPHLVLSNSPSKKVGANITNKFAKVIHQAPMLSLSNAFDEDDLRDFLERIKNFLRINEFTPIFCEPKIDGVSFSAIYKNGLFITGATRGDGYVGEDITMNIKTIKNFPHKIDNAPEFLEVRGEIYIEKQDFLNLNKEQEAQNRGKFANPRNAAAGSIRQLDVAITAQRPLKYFIYSGGVTEQNLASTQEQLLTKLKALSFSVNEISKLASSEEEIFAFYEYLKTNRHNLPYEIDGVVYKLNNFAMQNRMGFIARSPRFAIAHKFPAIIGQTKLLSITVQVGRTGMLTPVAELDPIEIGGVVVSRATLHNFQDIARKDVRIKDYVFLQRAGDVIPQITGVDISKRSNDTVKFDTPVFCPSCNSKLRYVSEDIIIRCDNGLNCPAQNYERICHFVSKNAMDIEGLGRKQVAFLIDKRLISNPLDIFFLKEKNETNLIRLENMDGWGKKSVANLFKNIEKSQKISLQRFIYALGIRHIGEQNAKLLAREFGSYNNFIAQMELLSKNDSDIYQKLNDLEGIGDKILVDIVDFFYVKENTQLIKRLGSVLNIEDYQETREQNILTGKIVVFTGSLSTISRVEAKEIAEKLGAKVTASVSLNTDLVIAGVNGGSKLKKAKELNIKIIDEVEWLAFIKNA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.