PharMolix/UniProtQA huggingface dataset:
Protein: METN_VIBCH
Sequence: MIEIKSVNKVFYQGDKQIHALKDINLFIPQGTIFGVIGSSGAGKSTLIRCVNMLEKPTSGQVIVDGVDLTTLSNPQLCAARRNIGMIFQHFNLLSSRTVFENVALPLELAGQSQQHIETKVTELLALVGLSEKRESYPANLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILELLKEINRQLNLTILLITHEMDVVKSICHEVAIIGGGELVEKGTVGDIFAHPKTELAHQFIRSTLDLSIPEDYQVRLQPTRVAGSYPLVRLEFTGATVDAPLMTQIARKYNIDVSILSSDLDYAGGVKFGMMVAEIFGNADDDEAAIRYLRENNVKVEVLGYVL
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1439_ARATH
Sequence: MASSKGGNTTAHINTLHHRLYHALNLGFRVCDEKEKKWKCTDIEIQRHVVKSISAFLDCFSRATANNRLIKDSISDIAGALVFILGSKNRAVVGLAANVVIRLIRIVPPSILHSYSLDLVESLSPLLCCQQFDVSLPCAVALNAILVNVRETKEKEVWKILEDEKTVVSVVGNLQIFSEGSMSVEWFQEMALLLSTIMLKWPQSRYSVWNNPALMGVLESVSQKPDMGLTVATLKLYSSLALCGHGANELLDNGKPMLDMMISCMEESSSQNARIEGLKLAQRLATGNRECLKMINMCSESLVKATVRTMGKWFLSSGKLELDQMSLLVEACKLALITRWEGQHHIYFWKYRISEALLSLVVENFHSQSLDGYVSLEEEVLVAEKVLNANFLPSLRSYVWDIIGFLAAHCEEEFDSILRGDELCLNFLVTCACLSFSRSVQKGYQICQNDIISASHSESASRAVLMMICSPSKYISSRARVTLSFILEEGGEQNLNSLVNFLSYIPSSGGYILPNILQTTVCLVGFACYSSIPQYASFILRKQGLEILLSFCSWYQRNWENIGASSFAPSSQSITEKRICCWVCTEDWDNKDAFLLYALLALAELVNHSFFGQNHAEELSMKSGNLKDRLCTTLKEIRDGTYGSGPRWYAAHILSYFGYYGFEHKLGKRLMCAYEDEEYSDMRLLFASGNSASVNKVIIAVRCPMLLPPKEGAHSSSTISTEKSQRTVQEIRMSANVDILALVKLLEFAYSGYVEVESTTLKKLKPLAKHCKAKVLLQMLCRRRPKWGSSIPEIDIPLALTPKLIHFSDVILVPKETNVACFNCRMCSLTSPHAHSHRVILSSGCEYLRALFRSGMQESHLDRLNVPVSWLGLTKLVSWFYSDELPKPPSGCKWNNMDTEAKLDELQAYVEIYSLSEWWIMEELQNDCAHVILSCLESARELSIKTIELAASFSMWKLVEAAANHAAPIYHQLRDSGELDELDDELVNLIRTAAVQFSQQGG
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At1g04390.
Protein: PURA_AGGAC
Sequence: QWGDEGKGKIVDLLTDRVKYVVRYQGGRGAGHTLILNGEKTVLRLIPSGILRDNVTCLIGNGVVLSPAALMQEMSELENRGVNVRDRLLISEACPLILPYHVAMDHAREARWAKRPIRATGRGIGPAYEDKVARRGLRVGDLFDRAAFAEKLKNILDYYNFQLVNYYKVEPVDYQKTLDDVFAVADIITGMVADITTILDTARKNGDNILFEGAQGTMLDIDHGTYPYVTSSNTAGGVASGSGFGPRNLDYVLGIIKAY
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHZ1_ASPCL
Sequence: MGDNNRATFSNDPAANAPDAAAVEKGKGKAVEEPALEMSMDEDEESEESEAEEIEDDEDDHDNLEPISQSNIIAGGRRTRGKTIDFQEAAEKLKDEMDEDDDDEDFEPNDNDMRN
What is the function of this protein?
Forms a chaperone-bound H2A. Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A. Z histone replacement in chromatin.
What are the official names of this protein?
Histone H2A.Z-specific chaperone chz1.
What is the protein family that this protein belongs to?
Belongs to the CHZ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOP3A_MOUSE
Sequence: MIFPVTLLAFQWHRRPGGRALSRAAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLRVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIKVTHDHKDGTVEFNWKRYRLFNHTACLVLYQLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQTVDPHWGAFAQTILERGGPTPRNGSKSDQAHPPIHPTKYTSGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWSDKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEMAQQEEIYPAMPEPVRKCPQCNKDMVLKTKKSGGFYLSCMGFPECRSAVWFPDSVLEASRDNSVCSVCQPPPVYRLKLKFKRGSLPPAMPLEFVGCIGGCDETLKEIFGLRFPRALPRASQPSGHLQASQALNRMDSSQHNLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCNCGREAVLLTVRKQGPNQGRHFYKCSNGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGSFAAPAWPGGRGKAQRPEAASKRPRAGSSDAGSTVKKPRKCSLCHQPGHTRTFCPQNR
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.  As an essential component of the RMI complex it is involved in chromosome separation and the processing of homologous recombination intermediates to limit DNA crossover formation in cells.  Has DNA decatenation activity.  It is required for mtDNA decatenation and segregation after completion of replication, in a process that does not require BLM, RMI1 and RMI2.
What are the official names of this protein?
DNA topoisomerase 3-alpha, DNA topoisomerase III alpha.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GPSB_BACC0
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: ATPG_RAT
Sequence: ATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARVYGTGSLALYEKAEIKGPEDKKKHLIIGVSSDRGLCGAIHSSVAKQMKNDMAALTAAGKEVMIVGIGEKIKSILYRTHSDQFLVSFKDVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNQFKSVISYKTEEKPIFSFSTVVAAENMSIYDDIDADVLQNYQEYNLANIIYYSLKESTTSEQSARMTAMDNASKNASDMIDKLTLTFNRTRQAVITKELIEIISGAAALD
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element.  The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, ATP synthase F1 subunit gamma, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ASNB_BACSU
Sequence: MCGFVGVFNKHPLAQTADQEELIKQMNQMIVHRGPDSDGYFHDEHVGFGFRRLSIIDVENGGQPLSYEDETYWIIFNGEIYNYIELREELEAKGYTFNTDSDTEVLLATYRHYKEEAASKLRGMFAFLIWNKNDHVLYGARDPFGIKPLYYTTINDQVYFASERKSLMVAQNDIEIDKEALQQYMSFQFVPEPSTLDAHVKKVEPGSQFTIRPDGDITFKTYFKANFKPVQTEEDKLVKEVRDAIYDSVNVHMRSDVPVGSFLSGGIDSSFIVSVAKEFHPSLKTFSVGFEQQGFSEVDVAKETAAALGIENISKVISPEEYMNELPKIVWHFDDPLADPAAIPLYFVAKEAKKHVTVALSGEGADELFGGYNIYREPLSLKPFERIPSGLKKMLLHVAAVMPEGMRGKSLLERGCTPLQDRYIGNAKIFEESVKKQLLKHYNPNLSYRDVTKTYFTESSSYSDINKMQYVDIHTWMRGDILLKADKMTMANSLELRVPFLDKVVFDVASKIPDELKTKNGTTKYLLRKAAEGIVPEHVLNRKKLGFPVPIRHWLKNEMNEWVRNIIQESQTDAYIHKDYVLQLLEDHCADKADNSRKIWTVLIFMIWHSINIEKRYMPEELSHQPKEVIFV
What is the function of this protein?
Main asparagine synthetase in vegetative cells.
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing] 1.
What is the protein family that this protein belongs to?
Belongs to the asparagine synthetase family.
Protein: HUTI_BACCR
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGVVGIENGVITFVGTAEEAKGLQAKEVIDSGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLVEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_MYCA9
Sequence: MTDTQVTWLTQESHDRLKAELDQLIANRPVIAAEINERREEGDLRENGGYHAAREEQGQQEARIRQLQELLNNAKVGEAPTQSGVALPGSVVKVYYDGDKGDTETFLIATRQEGVKDGKLEVYSPSSPLGGALIDAKVGETRSYTVPNGTEVQVTLVSAEPYHE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RECR_HAEIN
Sequence: MQSSPLLEHLIENLRCLPGVGPKSAQRMAYHLLQRNRSGGMNLARALTEAMSKIGHCSQCRDFTEEDTCNICNNPRRQNSGLLCVVEMPADIQAIEQTGQFSGRYFVLMGHLSPLDGIGPREIGLDLLQKRLVEESFHEVILATNPTVEGDATANYIAEMCRQHNIKVSRIAHGIPVGGELETVDGTTLTHSFLGRRQID
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MURC_BACC2
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKNNVEEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMSQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFADINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREVVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2R3B_HUMAN
Sequence: MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta, PP2A subunit B isoform PR48, Protein phosphatase 2A 48 kDa regulatory subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTRA_METMS
Sequence: MAEKREPAAGWPILKGEYDVGDPENCVAVITLGSHLDGGPMLEAGASITGPCKTENLGLEKVVSHIIANPNIRYLVVTGSEVKGHITGEAFIMLHKNGVSDNRIVNASGAIPYVENLTEEAVQRYQEQIECIDLIGTEDMGTISSKIKELAAKDPDAFDADPLVIEVGGEAEEEEEVGGLKPMASEISVIRGRILDIEREMARIGEFNKFHAGVHAGKFEGIMIGLAITLSLLGLILFGR
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL2_CHLSY
Sequence: MGVRIYKPTSAGRRNMSVSTFEEITKKEPEPRLIEPLRKKAGRNNQGRITVRHRGGGHKRFYRIIDFKRNKFGVPAKVQAIEYDPNRTARIALLAYADGEKRYIIAPLGLKVGDTVMSGPDAEIRVGNALPLSAIPLGTQIHNIELEIGRGGVLVRSAGTAAQLMAKEGDYAIVRMPSGEMRMIHLRCMATIGQVGNVDHQNIRLGKAGRSRWLGRRPRVRGAAMNPRDHPHGGGEGRAPRGMSTPKTKWGKPARGVKTRHNPRFDRFIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RPOC_PHOV8
Sequence: MAFRKETKIKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGPVKDYECHCGKYKRIRYKGIVCDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKIGYLLGLPTKKLDAIVYYERYVVIQPGVKAEDGINKYDLLSEEEYLDILDTLPKENQYLEDTDPNKFIAKMGAEAIYDLLSTLDLDALSYELRHKASNDSSQQRKNEALKRLQVVESFRASRGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQEAVDSLFDNSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIERGIVKTVKSAKKIVDRKEPVIWDILEHVMKGHPVLLNRAPTLHRLGIQAFQPHMIEGKAIQLHPLACTAFNADFDGDQMAVHLPLSNDAILEAQMLMLQAHNILNPANGAPITVPAQDMVLGLYYITKLRKGAKGEGLTFYGPEEALIAYNEGKVDIHAIVNVVVKDLDKDGKIVDVMMKETSVGRVIVNEIVPAEVGYLNTIISKKSLRDIISDVIKAVGVARACEFLDGIKNLGYYMAFKGGLSFNLGDIIIPKEKEELVKRGNEEVEQIMMNYNMGFITDNERYNQVIDTWTHVNSDLSDILYKTIKNDDQGFNSVFMMLDSGARGSKEQIRQLSGMRGLMAKPQKAGAEGAQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRRLVDVSHDVIINEEDCGTLRGLVCTALKNNDEVIATLYERILGRVSVHDIVHPTTGKLIVAGGEEITEDIAQEIEDSPIESVEIRSVLTCESKKGVCAKCYGRNLASSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGIAGNMAANASIVAKNNARLEFEELRTVDTVDEMGEAVKVVVGRLAEVRFIDVNTGIILSTHNVPYGSKLYAADGDIVEKGKLIAKWDPFNAVIITEATGKIEFESVVENVTYKVESDEATGLREIIIIESKDKTKVPSAHIVTEDGNLIRTYNLPVGGHVVVENGQAVKAGDIIVKIPRAVGKAGDITGGLPRVTELFEARNPSNPAVVSEIDGEITMGKIKRGNREIIVTSKTGEVKKYLVNLSKQILVQENDYVRAGTPLSDGAITPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVEIDEPGDTRFLEQQVVDKQEFMEENDRIWGKKVVVDSGDSQNLQPGQIVTARKLRDENSMLKRRDLKPVEVRDAIPATSTQILQGITRAALGTSSFMSAASFQETTKVLNEAAINGKVDRLEGMKENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANRKNVLDYSEVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RNPH_SHIF8
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SLYX_ERWT9
Sequence: MQYTQWEHRLDMLESKLAFQEHTIEELNLTVVQHELEMARLREQMRLLTDKLKAAAPSMIASQSEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: MTNN_LISMC
Sequence: MTIGIIGAMEEEVELLKNSMPSVEEIVIGGAKFYVGEIAGKEVVLLESGIGKVNAALGTTLMADRFKPEVIINTGSAGGMAEGLAVGDVIISDRLAYGDVDVTEFGYTYGQVPRMPAFYQGDAVLLKKAETIYREYFAASENKAVYGLVVTNDSFIMRPDQHETIRTFFPDVKAVEMEAAAIAQVAYQFDIPFLIIRAISDLANQEATISFDEFIHLAAKQSATCIIELLKTI
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: MORN_HUMAN
Sequence: QPPGGSKVILF
What is the function of this protein?
Stimulates the proliferation of neural cells.
What are the official names of this protein?
Morphogenetic neuropeptide, Head activator, HA.
Protein: RS15_IGNH4
Sequence: MNKRKEKGKSHSKRPVRNTPPRWVPFGPEEIKALIVELSKKGYGPSMIGIILRDQFGVPLVKPIVGKKLVKIMEEQGVAPPIPEDLFHLMKRAVRVRAHLAEHPKDKHSARGLMEIESKIRRLVKYYKRVGKLPPDWKYDPERARLLVQQYSALFESGA
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MBP1_YEAST
Sequence: MSNQIYSARYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAANFAKAKRTRILEKEVLKETHEKVQGGFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDFTQTDGSASPPPAPKHHHASKVDRKKAIRSASTSAIMETKRNNKKAEENQFQSSKILGNPTAAPRKRGRPVGSTRGSRRKLGVNLQRSQSDMGFPRPAIPNSSISTTQLPSIRSTMGPQSPTLGILEEERHDSRQQQPQQNNSAQFKEIDLEDGLSSDVEPSQQLQQVFNQNTGFVPQQQSSLIQTQQTESMATSVSSSPSLPTSPGDFADSNPFEERFPGGGTSPIISMIPRYPVTSRPQTSDINDKVNKYLSKLVDYFISNEMKSNKSLPQVLLHPPPHSAPYIDAPIDPELHTAFHWACSMGNLPIAEALYEAGTSIRSTNSQGQTPLMRSSLFHNSYTRRTFPRIFQLLHETVFDIDSQSQTVIHHIVKRKSTTPSAVYYLDVVLSKIKDFSPQYRIELLLNTQDKNGDTALHIASKNGDVVFFNTLVKMGALTTISNKEGLTANEIMNQQYEQMMIQNGTNQHVNSSNTDLNIHVNTNNIETKNDVNSMVIMSPVSPSDYITYPSQIATNISRNIPNVVNSMKQMASIYNDLHEQHDNEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDENGEAQTNDDFEILSRLQEQNTKKLRKRLIRYKRLIKQKLEYRQTVLLNKLIEDETQATTNNTVEKDNNTLERLELAQELTMLQLQRKNKLSSLVKKFEDNAKIHKYRRIIREGTEMNIEEVDSSLDVILQTLIANNNKNKGAEQIITISNANSHA
What is the function of this protein?
Binds to MCB elements (Mlu I cell cycle box) found in the promoter of most DNA synthesis genes.  Transcriptional activation by MBF has an important role in the transition from G1 to S phase.  It may have a dual role in that it behaves as an activator of transcription at the G1-S boundary and as a repressor during other stages of the cell cycle.
What are the official names of this protein?
Transcription factor MBP1, MBF subunit p120.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUG2_RAT
Sequence: MWKNREAQLCLFSVLLAFLPSASLLFGNSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLISQRGTRKLFDEPVVDKDLFHCVSFIPRLPSSEEEESLDINIEGAKHKFSKRHVVLVKNKESVVFVQTDKPMYKPGQSVKFRVVSMDKNLYPLKELVQDPKMNRIMQWQDVKTENGLKQLSFSLSAEPIQGPYKIVVLKQSGVKEEHSFTVMEFVLPRFGVDVKVPNAISVYDEIISVTACDRYTYGKPVLGRVKVRLCHGNPSFSSETKSACKEENSQLDNNGCSTQEVNITEFQLKENYLKVRQAFHVNATVTEEGTGMEFGGYGRIEVERTRNKFLFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEQVFIKAQEAGYTNATTTDQHGLAKFSIDTSSISGYSLNIKVYHKEENLCIHSSCTAERHAEAHHTAYAVYSLSKSYIYLDTEAGVLPCNQIHTVQAHFILKGQVLGVLPQIVFHYLVMAQGSILQTGNHTHQVESGAPVQGNFALEIPVEFSMVPMAKMLIYTILPDGEVIADSVKFQVEKCLRNKVHLSFSPSQSLPASQTHMRVTASPQSLCGLRAVDQSVLLLRPEAELSPSLIYDLPGMQDSNFIPRSHHPFEDEDDCLMYQPRDTEELTYSVPYGREKDVYRYVDMGLTAFTNLKIKHPTYCYDLPKEPPRKDPPRKDPEPKDTVVETIRNYFPETWVWDLVTVSSSGVTEVEMTVPDTITEWKAGALCLSNDTGLGLSSVATLQAFQPFFVELTMPYSVIRGEAFTLKATVMNYLPTSLQMTVQLEASPDFTAVPVGNDQDSYCLGANGRHTSSWLVTPKSLGNVNFSVSVEAQQSPEPCGSEVATVPETGRKDTVIKVLIVEPEGIKKEHTFSSLLCASDAELSETLSLLLPPRVVKDSARAHFSVMGDILSSAIKNTQNLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTENIKSKALGYLRAGYQRELNYKHKDGSYSAFGDHNGQGQGNTWLTAFVLKSFAQARAFIFIDESHITDAFTWLSKQQKDSGCFRSSGSLFNNAMKGGVDDEITLSAYITMALLESSLPPVVSKALGCLEASWETIEQGRNGSFVYTKALMAYAFTLAGNQEKRNEILKSLDKEAIKEDNSIHWERPQKPMKSEHYLYTPQASSVEVEMSAYVVLARLTAHPAPSPEDLALSTGTIKWLTKQQNSHGGFSSTQDTVVALDALSKYGAATFSKSQKTPSVTVQSSGSFSQKFQVDKSNRLLLQQVSLPDIPGNYTIRVSGEGCVYAQTTLRYNLPLEKQQPAFALKVKTVPLTCNNPKGQNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKPTVKKLERLEHVSRTEVTTNNVLLYLDQVTNQTLSFSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDKQNV
What is the function of this protein?
A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor.  While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.
What are the official names of this protein?
Murinoglobulin-2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.