PharMolix/UniProtQA huggingface dataset:
Protein: MAT1_MOUSE
Sequence: MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLENTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQEHEQRRLFIQKEEELQQALKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPRSMKPVTFSTGIKMGQQISLAPIQKLEEALYEYQPLQIETCGPQVPEQELLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPR
What is the function of this protein?
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.  CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation.  CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts.  Involved in cell cycle control and in RNA transcription by RNA polymerase II.
What are the official names of this protein?
CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Menage a trois, RING finger protein MAT1, p35, p36.
What are the subcellular locations of this protein?
Nucleus.
Protein: F90AI_HUMAN
Sequence: MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLKFPKKPRLGPFQIPESAIQGGELGAPGNLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Protein FAM90A18.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: RL21_ENTH1
Sequence: MPLSNGRNRRTRKLFKRPFRGHGLSNTSTILHTYKVGDYVTILCNSSIQHGLPYKAFHGKTGRVWNVNPHAIGVMVNKKVNNRIVVKRLHISPEHIRPSGCQKDFLERKAAVAAIRKQNIQLKKEGKPLLPLPAKRLPKQPRPAELIKGADIKFTTVAPLKFEELY
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: SLS1_CATRO
Sequence: MEMDMDTIRKAIAATIFALVMAWAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDVKESGKMHQEALSKPMEFNNDIVPRLMPHINHTINTYGRNSFTWMGRIPRIHVMEPELIKEVLTHSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHDMLTKWEKIAEKQGSHEVDIFPTFDVLTSDVISKVAFGSTYEEGGKIFRLLKELMDLTIDCMRDVYIPGWSYLPTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGEDDLLGVLLESNIQEIQKQGNKKDGGMSINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKLES
What is the function of this protein?
Component of the seco-iridoid and derivatives monoterpenoid indole alkaloids (MIAs, e. g.  secologanin) biosynthesis pathway.  Catalyzes the conversion of loganin into secologanin (PubMed:11135113, PubMed:26285573).  Catalyzes the conversion of secologanin into secoxyloganin (PubMed:26285573).
What are the official names of this protein?
Secologanin synthase 1, CYPLXXII, Cytochrome P450 72A1, Secologanin synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: GUAA_SCHPO
Sequence: MSSTEVPGEVSTSVSSYFDTILILDFGSQYSHLIARRLREIHVYAELLPCTQKIEALPFKPIGVILSGGPYSVYDDIAPHVDPAVFELGVPVLGICYGMQEIAWLNGRCVEPGIEREYGPATVSMEPEIKTEVFKSFFNSMPKEFEVWMSHGDRLSALPNGYETIGRTKNSPFAVIAHVTKPIIGLQFHPEVTHTPLGLQLIKNFAIEICHAKPNWSMENFVDKEILRIRKMIGPSDHVIGAVSGGVDSTVASKVLKEAIGDRFHAIMVDNGLLRLNEAEIVRETLNKHLGIQLTVVDASEEFIGKLKGVTDPEKKRKIIGNTFIHVFEREAERIVKETNGKVEYLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLKDMKLKLIEPLRELFKDEVRALGELLGIEHSLVWRHPFPGPGLGIRILGEVNAAQLEIARKADHIFITEIRNHGYYDKISQAFAALLPVKAVGVMGDKRTHEQVIALRAITTSDFMTADWYDGFSIKFLKLVSSRICNEVSGVNRVLYDISSKPPATVEME
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3002R_ASFB7
Sequence: MITLYEAAIKTLITHRKQILKHPDSREILLALGLYWDKTHILVKCRECGKMSLTGKHSTKCININCLLILAIKKKNKRMVDTLIRMGADVTYIHLLKNKIKLSYNQLSMLKSNSQISLKELHAICYLLYGRLPKKIKQGMQLCKTMAGLCGELL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 300-2R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 300 family.
Protein: ALR_FRATT
Sequence: MNILKISKQTLRNNIKIIREYIGNAKMCFPVKANAYGHGIEDIVENTHDLVDFFAVANSLEAFRVTAVAKNPVLVFGVIYYEYIEKMISENIRVSIQDYEDIEKLEQIAKELDKKVYAHININTGMNRMGVDYNDACRTIQRAYESDWLILEGVYSHLACADNRDHPTNIKQKNRFDSIVKFTKGLSQDIICHLSNSYGFLGQKGICYDMVRPGILSYGFLPEFYVDRVIREIKPIARLLSKVVKIITLQEGEGVGYSLIYRGFEDEQLAVIPIGYGDGFPRELGDRGFVNINDVMYPMAGRMSMDGLTVSLGINEYDVKVGDTVELISAIPRNRNSAFSIAKQTNTIEYDIMSTLNDRIIRKII
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RS8E_PYRHO
Sequence: MAIWQGRSLKKPSGGRIVLARKKRKRELGREPSNTRVAEQDKRKIIRTYGGNRKVRLTAAAYANVFDKSGKGRKVRIIRVLENPANRQFARRNIITKGAIIETEIGKAKVTSRPGQDGVVNAILLEE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: PLPP_MOUSE
Sequence: MARCERLRGAALRDVLGQAQGVLFDCDGVLWNGERIVPGAPELLQRLARAGKNTLFVSNNSRRARPELALRFARLGFAGLRAEQLFSSALCAARLLRQRLSGPPDASGAVFVLGGEGLRAELRAAGLRLAGDPGEDPRVRAVLVGYDEQFSFSRLTEACAHLRDPDCLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITEDFSVDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIADLMEGLED
What is the function of this protein?
Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism (PubMed:24338473, PubMed:24338687, PubMed:25783190).  Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN.  Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis.  Does not dephosphorylate phosphothreonines in LIMK1.  Does not dephosphorylate peptides containing phosphotyrosine (By similarity).
What are the official names of this protein?
Chronophin, Pyridoxal 5'-phosphate phosphatase, Pyridoxal phosphate phosphatase, PLP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Diffusely distributed throughout the cytosol during pro-metaphase and metaphase. Detected at the dynamic cell poles during telophase. Detected at the cleavage furrow and contractile ring during cytokinesis. Transiently detected at the plasma membrane in late stages of cytokinesis. Detected at the midbody.
Protein: LEXA_ANADF
Sequence: MDALTDRQLEVLRFIARQIEDNGYPPTIREIGEALDIRSTNGVNDHLKALERKGFLTRDPVKSRALIPTPQAREVLGGGARASNVVPFTRTPAVGLKPAGRLVEIPILGRVAAGQPILAQERVEDTVQVDSFLLGTNKKVYGLRVQGDSMIGDGILPGDYIFVKKQLHAEDGDIVVAMIDEEATVKRVYFEGDRVRFQPSNPRMAPIYVRGSDFRTTMILGVVVGVYRKLG
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: STPG4_HUMAN
Sequence: MDQPAVATASTSIREDLVGGESFITASKPAQKTSSFEREGWWRIALTDTPIPGTYHLKTFIEESLLNPVIATYNFKNEGRKKPPLVQRNNPVLNDLPQYMPPDFLDLLKKQVATYSFKDKPRPSPSTLVDKDQSLQLSPGQYNVLPAPVPKYASRSCVFRSTVQRFPTTYFIPHEGPGPGHYNVKMPPTSSVTSCFQSRVPRFLPSCSKTPGPGAYTTLRQFPKQSPTIAKMGQEHSLFFNNNNWLLK
What is the function of this protein?
Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote.  Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC).
What are the official names of this protein?
Protein STPG4, Gonad-specific expression gene protein, GSE, Sperm-tail PG-rich repeat-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in female and male zygote pronucleus. Associates preferentially with the paternal chromatin during zygote development.
Protein: EFTU_STRSY
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGLQEEKSKAVVTGVEMFRKQLDEGLAGDNVGVLLRGVQRDEIERGQVISKPGSINPHTKFKGEVYILTKEEGGRHTPFFDNYRPQFYFRTTDVTGSIKLPEGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_GLOC7
Sequence: MGAIQALRGTRDILPHEVGYWQQVERVAAEILSRALYLEIRPPIFEQTALFERGIGEGTDVVGKEMYTFKDRGDRSITLRPEGTAGVVRSFIEHNLYATGGVQRLWYTGPMFRYERPQAGRQRQFHQIGLELLGSGDYRADVEVIALATDILQTLGLKNLKLDLNSVGNREDRQNYRQALVDYLTPYKAQLDPDSQDRLERNPLRILDSKDERTKIICQDAPSILEYLGTESKRHFEQVQQLLGDLNIKYQLNPCLVRGLDYYTHTAFEIQSDDLGAQATVCGGGRYDGLVVELGGPATPAVGWAIGMERLILLLQQLQSTPTLTPDIYIVSRGEKAESQGLILAQKLRHWGLSVELDLSGSAFGKQFKRADRTGAIACLILGDQEAENQTVQLKWMTSSQQQTLTQVELLSQLEELKQSFDRHRQSRDD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ACIBC
Sequence: MAIERTLSIVKPDAVSKNHIGEIFARFEKAGLKIVATKMKHLSQADAEGFYAEHKERGFFGDLVAFMTSGPVVVSVLEGENAVLAHREILGATNPKEAAPGTIRADFAVSIDENAAHGSDSVASAEREIAYFFADNEICPRTR
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FASTK_HUMAN
Sequence: MRRPRGEPGPRAPRPTEGATCAGPGESWSPSPNSMLRVLLSAQTSPARLSGLLLIPPVQPCCLGPSKWGDRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRPRPPPVEQVTLQDLSQLIIRNCPSFDIHTIHVCLHLAVLLGFPSDGPLVCALEQERRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQQFMPCLERILAREAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGLPQLKSYLRQKLQALGLRWGPEGG
What is the function of this protein?
Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels.
What are the official names of this protein?
Fas-activated serine/threonine kinase, FAST kinase.
What is the protein family that this protein belongs to?
Belongs to the FAST protein kinase family.
What are the subcellular locations of this protein?
[Isoform 4]: Mitochondrion matrix. Note=Colocalizes with mitochondrial RNA granules.
Protein: XNI_SHEB5
Sequence: MNKFLIIDGLNLVRRIYAAIPDETDMQSLTERVISACTKLLRVHRPTHVAIVWDGHEISWRKQLYPDYKKGRKPMPEPLAQGLVALQDHLTAMHIGSIYAAAEADDVIATLAIKTAKAQGEAIIVSTDKGFSQLNHRHISQWDHFNQQYLDIAALEQKLGVERSQFLDLMALAGDSGNKIPGIAGIGPKSAAELLKTFRSLPTLFSSLSNLGAKQAKKLAEGKEMARLSYKLAQLQTDLPLNINLKDFRVIDSPPEKTINQD
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: ILVE_SALTY
Sequence: MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPVVFRHREHMQRLRDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLVFVGDVGMGVNPPPGYTTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDKWGWLDPVNS
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase, BCAT, Transaminase B.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: GRCA_SALEP
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: CNRB_DICDI
Sequence: MNNQGGAVAANGQRPQAQQQQQQGGIMGIISTLIRFMAIYYIASFAFSKFLGTGNNNNNGGVVLNNNNGTTNTSIPSNSVRLANSWPEGIEFNMKVYLSTSNETVGDWLVWEQDKLSYDWKDSNTIPTKNITFDTTPYLQNNGSLFAHIITSRRAYLNQPKSQLHKVHPLIVYLPKPKPKGKNLLEEKSKDEPEVEYDPTELISYWKPTLSLHLIVDHTIYPPDSIPKEIVSYFNITNGFYSPIIYCNEFWLYREHLKPVNETVKQLSIEINYSSMGLFKWQLQIQMQKSLDMQESFGGGGNSAMGGASVGDEFKRMLTDNDPWILGLTLIVSVLHTIFEFLAFKNDIQFWKNNKSMEGLSVKTITLNCVCMGIIFLYLLDNETSYMILASSGFGFLVEFWKLGKAMTIKITWMTSLPLPKRIEFINKDEYMSKTKQYDDMAMKYLSWLLFPLVIGTSIYSLYYHEHKSWYSWVVSSLVRTVYTFEFIMMTPQLFINYKLKSVSHLPWRVFMYRALNTFIDDLFAFIIKMPLLHRLSCLRDDIIFIVYLYQRWIYPVDKKRSHYGSEEAEEVQQQDKKEIKEKVEEREEEKQEEEEEEKEKEEESTSSSKVTKRKTKKV
What are the official names of this protein?
CLPTM1-like membrane protein cnrB.
What is the protein family that this protein belongs to?
Belongs to the CLPTM1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KPRS2_STRP6
Sequence: MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_CAMJR
Sequence: MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGNFLELCGSVSLYPESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIRALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVADFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_PSEPF
Sequence: MSESVDSVELFTDGACKGNPGPGGWGALLVCKGVEKELWGGEANTTNNRMELLGAIRGLEALKRPCEVLLVTDSQYVMKGINEWMANWKKRGWKTAAKEPVKNADLWKALDEQVNRHKVTWKWVRGHIGHHGNERADQLANRGVDEVRGYKQS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPKOW_MOUSE
Sequence: MAGRESPPPSAPSMAPISFGFTRTSVRRRLADLGDSERQAPEEKDFLATVEGRKLQSVNPPEAPKELVIPLIQNGSRRQPLSKNPKPSSETSTVLMSDGVLSQAVKELIEESKKSLEERENAGVDPTLTIPMIQKGCTPIEEGSDSEPQAETVPEEADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANRMEAQDLASVGSHHPPRPDGDRENDKEGQPQGLMHGRAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAVGNRIVTVSEYCLRPVSQQEFDSHTSKPGHVSQTSTEQQNRATGTASSLKAAQNQEDSKRRQKGSEKKRKHSPDRQDGPVPKTEKAAPRNKHWLHRDLRVRFIDKLHKSGRYYNTKMTIEDVLSPDTCVCRTDEGRVLEDVREDMLETLIPKGEGHRVMVVLGPHAGKVGLLRSRDRAQSHALVQLRRENQVVELHYNAICQYMGPGDSDED
What is the function of this protein?
RNA-binding protein involved in pre-mRNA splicing.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
G-patch domain and KOW motifs-containing protein, Protein MOS2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MOS2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZN862_HUMAN
Sequence: MEPRESGKAPVTFDDITVYLLQEEWVLLSQQQKELCGSNKLVAPLGPTVANPELFRKFGRGPEPWLGSVQGQRSLLEHHPGKKQMGYMGEMEVQGPTRESGQSLPPQKKAYLSHLSTGSGHIEGDWAGRNRKLLKPRSIQKSWFVQFPWLIMNEEQTALFCSACREYPSIRDKRSRLIEGYTGPFKVETLKYHAKSKAHMFCVNALAARDPIWAARFRSIRDPPGDVLASPEPLFTADCPIFYPPGPLGGFDSMAELLPSSRAELEDPGGDGAIPAMYLDCISDLRQKEITDGIHSSSDINILYNDAVESCIQDPSAEGLSEEVPVVFEELPVVFEDVAVYFTREEWGMLDKRQKELYRDVMRMNYELLASLGPAAAKPDLISKLERRAAPWIKDPNGPKWGKGRPPGNKKMVAVREADTQASAADSALLPGSPVEARASCCSSSICEEGDGPRRIKRTYRPRSIQRSWFGQFPWLVIDPKETKLFCSACIERPNLHDKSSRLVRGYTGPFKVETLKYHEVSKAHRLCVNTVEIKEDTPHTALVPEISSDLMANMEHFFNAAYSIAYHSRPLNDFEKILQLLQSTGTVILGKYRNRTACTQFIKYISETLKREILEDVRNSPCVSVLLDSSTDASEQACVGIYIRYFKQMEVKESYITLAPLYSETADGYFETIVSALDELDIPFRKPGWVVGLGTDGSAMLSCRGGLVEKFQEVIPQLLPVHCVAHRLHLAVVDACGSIDLVKKCDRHIRTVFKFYQSSNKRLNELQEGAAPLEQEIIRLKDLNAVRWVASRRRTLHALLVSWPALARHLQRVAEAGGQIGHRAKGMLKLMRGFHFVKFCHFLLDFLSIYRPLSEVCQKEIVLITEVNATLGRAYVALESLRHQAGPKEEEFNASFKDGRLHGICLDKLEVAEQRFQADRERTVLTGIEYLQQRFDADRPPQLKNMEVFDTMAWPSGIELASFGNDDILNLARYFECSLPTGYSEEALLEEWLGLKTIAQHLPFSMLCKNALAQHCRFPLLSKLMAVVVCVPISTSCCERGFKAMNRIRTDERTKLSNEVLNMLMMTAVNGVAVTEYDPQPAIQHWYLTSSGRRFSHVYTCAQVPARSPASARLRKEEMGALYVEEPRTQKPPILPSREAAEVLKDCIMEPPERLLYPHTSQEAPGMS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 862.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALG8_BOVIN
Sequence: MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSPFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ
What is the function of this protein?
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity).  Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (By similarity).
What are the official names of this protein?
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8 homolog, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RBS_THANO
Sequence: MRLTQGCFSFLPDLTDTQIEKQVAYAMNKGWAMNVEWTDDPHPRNNYWELWGLPLFDIKDPATVMFELNEARKSCASGYIRINAFDASYGVESCVMSFITNRPATEPGFYLDRTEGPGRQVIYSIKSYSVQANPEGSRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BZTC_RHOCB
Sequence: MSDTSFVRTEMLAPRPAPVSQVGAIKWMRENLFSGPLNTALTVFGLLATVWLVQAAAPWLLHGVWNANSLTECRAIIAERWGPEATGACWAVIRVRWNQFLFGFYPVDQYWRLFVTFAGLFLALAPVLFDALPRKLIWGTLLYPLAAFWLLWGGPIWGPVSVLAGFAILGLLFTALAPKLGVPVSAGIGLVVAALFWLYAAAPIEAALQSALPLALPEVDSDQFGGFLLALVIGVTAIVVSLPLGILLALGRQSDMLIVKSLSVGIIEFVRGVPLITLLFTASLLLQYFLPPGTNFDLILRVVILVTLFAAAYIAEVIRGGLAALPRGQYEAADALGLDYWQAQRLIIMPQALKISIPGIVSSFIGLFKDTTLVAFVGLFDPLKGISNVVRSDMAWKGTYWEPYIFVALIFFLFNFSMSRYSMYLERKLKRDHR
What is the function of this protein?
Part of a binding-protein-dependent transport system for glutamate, glutamine, aspartate and asparagine.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutamate/glutamine/aspartate/asparagine transport system permease protein BztC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.