PharMolix/UniProtQA huggingface dataset:
Protein: DHPS1_MYCTO
Sequence: MSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG
What is the function of this protein?
Is involved in the bioactivation of the antituberculous drug para-aminosalicylic acid (PAS).  PAS is a close structural analog of pABA and acts as an alternative substrate for DHPS, leading to hydroxy-dihydropteroate (H2PtePAS).  Metabolomic studies show that PAS, despite its in vitro activity as a competitive inhibitor of DHPS, does not inhibit growth of M. tuberculosis by inhibiting DHPS.  PAS exerts its antimycobacterial activity through its effects on M. tuberculosis folate metabolism downstream of DHPS.  PAS poisons folate-dependent pathways not only by serving as a replacement substrate for DHPS but also by the products of that reaction serving as replacement substrates and/or inhibitors of subsequent enzymes.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: SLMA_YERE8
Sequence: MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDSLMSRINLILQDEKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEVQLRQVLREKKLRDGQGFIHDEALLATQLLAFCEGMLSRFVRSEFRYRPTQEFDARWPLIVAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AMPA_PSEP1
Sequence: MELVVKSVAAASVKTATLVLPVGENRKLGAVAKAVDQASEGAISAVLKRGDLAGKPGQTLLLQNLPGLKAERVLLVGSGKEEALGDRAWRKLVASVAGVLKGLNGTDAVLALDDIAVSNRDAHYGKYRLLAETLLDGEYVFDRFKSQKAEPRALKKVTLLADKAGQAEVERAVKHASAIASGMAFTRDLGNLPPNLCHPSFLAEQAKELGKAHKALKVEVLDEKKIKDLGMGAFYAVGQGSDQPPRLIMLNYQGGKKADKPFVLVGKGITFDTGGISLKPGAGMDEMKYDMCGAASVFGTLRAVLELQLPINLVCLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDTLTYAERFKPQAVIDIATLTGACIVALGSHTSGLMGNNDDLVGQLLDAGKRADDRAWQLPLFDEYQEQLDSPFADMGNIGGPKAGTITAGCFLSRFAKAYNWAHMDIAGTAWVSGGKDKGATGRPVPLLTQYLLDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN214_HUMAN
Sequence: MAVTFEDVTIIFTWEEWKFLDSSQKRLYREVMWENYTNVMSVENWNESYKSQEEKFRYLEYENFSYWQGWWNAGAQMYENQNYGETVQGTDSKDLTQQDRSQCQEWLILSTQVPGYGNYELTFESKSLRNLKYKNFMPWQSLETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVEEALPQYVGVICQEDLLRDSMEEKYCGCNKCKGIYYWNSRCVFHKRNQPGENLCQCSICKACFSQRSDLYRHPRNHIGKKLYGCDEVDGNFHQSSGVHFHQRVHIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEKPFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKCEDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECGKGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFSHSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSHLHNNHRRGNL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 214, BWSCR2-associated zinc finger protein 1, BAZ-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOD_CROS8
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKHIAETFLEDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVRADVKLRDVVIGMGACTDSKVNRLRFKDHDFAAIADFDMVRNAVDAAKALGVEARVGNIFSADLFYTPDPSMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RS18_RICAE
Sequence: MLKSNNTSETAAHKVGDKTAKKVFFRRRKGCPLSVPNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ENO_SCHMA
Sequence: MSILTIHARQIFDSRGNPTVEVDLKTSKGLFRAAVPSGASTGVHEALELRDTNSKAYMKKGVLTAVSNVNKIIAPALINKNIPVTNQAAIDKYMIDLDGTENKEKLGANAILGVSLAVCKAGAAEAGLPLYRYIARLAGHEDVIMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFTEAMQIGTEVYHNLKAVIKREYGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEIGMDCAASEFHKNGKYDLDFKNPHSAESTWLSPDAMANMYKQMISKFPIVSIEDPFDQDDWETWPKLTSSTNIQIVGDDLTVTNPKRIKQAIASKACNCLLLKVNQIGSLTESIEACKLAQDSGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSDRLAKYNQLLRIEEELGTAAKYAGKNFRHPKV
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRTL_HALH5
Sequence: MTEQELQQLVEDISLKSFGMKFRHKARFNPRLRTTGGRYLLHSHDIELNPKHLELFGLDELIGIIKHELCHYHLHLQKKGYHHRDADFKLLLKEVDAPRYCAKIPHAQNSVKTRHLYVCTGCGTRFERKREVDTSRYVCGKCNGRLKKIKG
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
Protein: RL7_YERPE
Sequence: MSTITKDQILEGVAALSVMEIVELISAMEEKFGVSAAAVAAGPAAAVEAAEEQTEFDVVLASFGENKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGVNKDEAETLKKSLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ACP_CLOAB
Sequence: MVFEKVKDIIADQLGIDATEIKMESSFIDDLGADSLDIVELIMALEEEFDIEMPDEEAEKVSSVGDVVNYIKAHTEE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CLOB6
Sequence: MKENKIRKNKEFRHVYRRGKSYSNKLLVLYVCKNRYNINRLGVSVSKKVGKSVVRNKVKRLIKESYRLNLDKDMKRGYDLVFIARNSSNDKDYKDIESALINLLKKAGIYN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RR4_HELAN
Sequence: MSRYRGPRFKKIRRLGALPGLTNKRPRAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMAPTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDTIAARDEQKSRALIQNSLDSSPPEELPNHLTLQPFQYKGLVNQIIDSKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SBDS_CHICK
Sequence: MSIFTPTNQIRLTNVAVVRARRAGKRFEIACYRNKVMGWRSGAEKDIDEVLQTHTVFVNVSKGQVAKKEDLVRAFGTDDQTEICKVILSKGELQVSDKERQTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIRQLKETMQIERAHMRLRFILPVKEGKKLKEKLKPLIKVIENEDFHDQLEIVCLIDPGCFREIDELIRSETKGKGTLEVLSLKDVEEGDEKLE
What is the function of this protein?
Required for the assembly of mature ribosomes and ribosome biogenesis.  Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.  Required for normal levels of protein synthesis.  May play a role in cellular stress resistance.  May play a role in cellular response to DNA damage.  May play a role in cell proliferation (By similarity).
What are the official names of this protein?
Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SDO1/SBDS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (By similarity).
Protein: OCA5_KOMPG
Sequence: MSQNSSIGKGNQSPPLFDLYEGHQEGSETEATSAAKYPNLFKSETTITDLPELVKLLHKFLETKNVTGLALIARQKGLPPSMRAKVWPLLLRTHPFVLKPYITSDDDDGDDVDGEEEEQEDDLHSSTPDNSTTSSNDTEGSDNEYPSSIPIHRIRSELQRYTIRSNYNKDIIMSLSPQVRQLFEVQEQIFHTIERAVARFLKKWGSIVHYDPGLVWLGLALAEWIPPLPEYSYILCGREHVARNGTKLRDINDDNFQRLYVNDDISSIILNYQSEDAKFSINENKEPSNDKSNKHQKNLSFAELYERMVLVVLHSPEQSDVVETDSMHERTNNILQTIPTKGGSISERVSFFLHCFRHLLPELSNYFSEEDILNGYNNSDEWVIWWLKWGGARAWSRFDRGRVWDYLLGWRNGLPANPNSKTEILRHQEELEEVRSCLDSHTLELLGPDLFWNPLVKEDVDSTKKPEPESCALSRKESLKSMLSTLSLTNNTALEWSSSSVGLDERERQSNHRDTLLQIPYSQIDPHSALVFIAVAFLKSKEFALLELESTEILEFLNKSSSLKFNGFQSLISDPKWDTEDADVRKIMDSYNNSPEDRDVRHLPSSGISYTAEKDSKTNSKGKRAFSPSPPSDLSLTGRYRSQPKRSPRGIENVITEAGELWRKWSWQELVEDN
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORR33_ORYSI
Sequence: MDQARISFFPDGLRVMIIDDDAKAVRRATATLSQLQYAVVATHSTASAGLRALSGDNVVEIQAILCDVHKVVSSGFDFRRVVESELRIPVIYLLSKMEEEDMVAGEDAEFLNHLLLTATYIVRKPLNPTVMARLWRVVAWRMYCLEERIQANVAANAGAGGEDDDDDDDVVIVEEPQVHFKVVRRTSGGSRKRQLTINVVDDGNRGSGSGGGGGGGADANPTRILQHITSNLQEFRTKHQKKDMAIERPLISSDSMFLKAILPTLKISPCNPLILTGGIGSSSVAAEAFAGGSSSAAPLQIPVFQQQSTGNGNTVISFSNNASPMAMRAPTDNTMISFNNVSAAPVANAVISFSNISRSAAMQAPAARGQHLSGDVQQLDFPQQKLYFGPFSYQGPPPPSMHNHINLLPPTSSPVTCSMDKGKVPIIELPYGMPVDDFLVGQTAYGGAGLSIGATDAAATAYPYTDAPSNNVATGCLMVPRMGPAFSITEPTVVAQGEGIGTGVDAGTSEKNAIVEAPNNPAPLMVLDQVAADAAMDVEEDIMFSLESLLGPDYDLLPMEDVSAPDTAAAGDAAGGSLDGEEGGMDIGWDLDLDDILVENVNDFAFLDNLAGSE
What is the function of this protein?
Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  May directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ORR33.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
Protein: YQGF_HAEI8
Sequence: MGITALAFDFGTKSIGCAIGQSITGTAQALPAFKAQDGIPNWEAIEKCLKEWKPDVVIVGLPLNMDGTEQDLTLRARKFANRLQGRFGVNVHLQDERLTTTQARSEIFERGGFKALKKGKIDGVSACLILESWFEYAEY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_GEOSL
Sequence: MSRKATIERVTKETQIKLSLEIDGTGEAKICTSVPFLDHMLDLFARHGLFNLQVDATGDIDIDFHHTVEDIGIVLGQALKEALGDKKGIRRYGQATVPMDETLASVAVDISGRPYLVYHVSLPKVKIGEFDVELVREFFQAVVNNLGANIHVNVMYGDNVHHIVEACFKAFARAVDQATQVDSRIQGVMSTKGKL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_THENN
Sequence: MYRVRVFGDPVLRKRAKPVTKFDEALKRTIERMIETMYHYDGVGLAAPQVGISQRFFVMDVGNGPVAVINPEILEASPETEIAEEGCLSFPEIFVEIERSKRVKVRYQNVRGEFVEEELEGYPARVFQHEFDHLNGVLIIDRIKPAKRLLLRKRLMDIAKSARG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: GLMM_PHOLL
Sequence: MSNRKYFGTDGIRGKVGDSPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESSLEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPYYDNGIKFFSIDGTKLPDDVEEAIEAEMEKPLTCVESAELGRANRIVDAAGRYIEFCKGTFPSEQSLNGLKIVLDCANGATYHIAPNVLRELGADVVTIGCEPNGININEKCGATDVRLLQQRVVEEKADVGLAFDGDGDRVIMVDHLGQKVDGDQILYIIAREALRQGQLRGGVVGTLMSNMGLELALKQLGIPFLRAKVGDRYVLEKLQEEGWRLGAENSGHVILLDKTTTGDGIVAGLQILSAMVRNHMSLHDLCSGMKLLPQVLVNVRFSGSHDPLKSENVINITKSVETELNGRGRVLLRKSGTEPLIRVMVEGEDDVQVTALAHRIADAVKHAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RU1C_HUMAN
Sequence: MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPAT_OCEIH
Sequence: MTSSKLDQFLQENISDLKDRGLYNEIDTVQGANGPEITIEGKKLINLSSNNYLGLATNNEMKEIAKKAIDSHGVGAGAVRTINGTLDLHIELEKKIAQFKGTEAAIAYQSGFNCNMAAISAVMDKNDAILSDSLNHASIIDGCRLSKAKIIRFEHSDMNDLRQKAKEAVESGQYNKIMVITDGVFSMDGDIAKLPEIVDIAEEFDLITYVDDAHGSGVTGDGAGTVKHFGLQDKVDMQMGTLSKAIGVIGGYVAGKQSLIDWLKVRSRPFLFSTAVSPADAVASKRAIEMLMESTELNEKLWENGDYLKQGLKELGFDIGESETPITPCIIGDEKKAQEFSKRLYEEGVYAKSIVFPTVPRGTGRVRNMPTAAHTKEMLDDAIAIYKKIGQEMKLI
What are the official names of this protein?
Putative pyridoxal phosphate-dependent acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: BIOB_SULNB
Sequence: MSTRKQIFLCAINNILSGTCKEDCKFCTQSVRYHADIERYSYKKIGQIVEEARQAKANGALGYCLVTAGKGLDDKKVDFVARAAQAVKAEVEGLNLIACNGTASLEQLIYLKEHGIDSYNHNLETSERYYPEICLTHGWQERYETCENVKSSGLALCSGGIFGMGESMKDREDLLSAIASLQPESTPLNFYHPNPALPIKTRNIGFEEALNIIRRAHTLLGEDRLLMVAGGRELLFNGKEDEMFKAGANSIVIGDYLTTSGSAPKMDQLMLEKLGYEVATSCDSH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: FTSB_SALTI
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: AMPP1_LACBS
Sequence: MWRAIWLRISEKGLRRPPPPSLRTVTTSCTTMGADGVHTVNTTERLAKLRELMKQHSVQAFVVPSEDQHSSEYLANCDKRRAFISGFDGSAGCAIITTDKAYLFTDGRYFLQAEKQLDKNWKLMKQGLPDVPTWQDFLYKNLGPHTQIGIDATLLAASDAESLTKQLTPKYSKLVSLKENLVDVVWGEDRPSRPQNSVFHLDVKYSGQSHLDKIATLREEMKKKKAEAIVVTMLDEVAWLLNLRGSDIEYNPVFFAYAVVTMDEVILFIDSAQLDDTARHNLEHVYTMPYEAIFEHLNSLSRTLELDRDSKVLIGDRASLAVADAIGKDNYTIVRSPIADLKAIKNKTELEGFRQSHIRDGAALVRYFAWLEEQLNHGTVINESQGADKLEAFRSELDLFRGLSFDTISGTGPNGAIIHYKPDPNDCAIIKKDQVYLCDSGGQFLDGTTDVTRTWHFGTPTDEEKRAFTRVLQGHIAIDTAVFPNGTTGYVIDAFARRALWQDGLDYRHGTGHGVGHFLNVHEGPHGIGVRIALNNTPLKAGMTVSNEPGYYADGKFGIRIESIVLVREVKTPNNFGDKGYLGFENVTMCPIHKNLVDVSLLNEQEKKWLDEYHAETWDKVSPLLKGDTRALEWLRRECSPL
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RSMH_YERPB
Sequence: MVDNNKTVDNNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVGKMMPGDAEIAENPRARSSVLRFAERIGE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3909_SHEPA
Sequence: MKNKIAINQVRSFLLSIWAFFLHLLSRFKEDQVNIKAGHLAYVTLLSLVPIVAVMFSMLSAFPVFSGIREKLEGFVYDNFLPAAGDTVQIYINEFVANASKGTSVGIVALMVVALMLISAIDKALNSIWRTKEKRQAAVSFSMYWMVLTLGPVLVGASLVATSYIVSLKLFSETELSGVVPILIERLPMLFSVAAFLLLYMVVPIKKVKFLHALLGALVAAMLFELGKKGFAFYVTQFPSYEAIYGALATIPILFVWVYVSWVIVLVGAEITAGLPEYLHECKLIRETALAESQAETKTEEPVTESKNDGPNSSNDSGQDNVRGSEKTDEPAQDKQDKLD
What are the official names of this protein?
UPF0761 membrane protein Spea_3909.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NACA_CHILA
Sequence: MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEGQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIEWVMSQANVSRAKAVRALKNNSNNIVNAIMELTM
What is the function of this protein?
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER).  Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.  Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).  May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus.
Protein: ZAPA_YERPE
Sequence: MSAQPVDIQVFGRSLRVNCPPEQQDALNMAAEDLSQRLQDLKVRTRVNNTEQLVFIAALNVCHELAQERLKTRDYASNMEQRIRMLQQTIEQALLEQGRISDRQDTQFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: AROA_CHLPD
Sequence: MSVFKGEVTALPPDKSISHRAALIGALSDGTTEIVNFSGGFDNQSTLAVLQASGIALIQEECAGSYGRRIRRVVIESRGLWSFLAPQAPLMCNNSGSTMRMFAGILAAQPFESVLEGDSSLMKRPMNRVADPLRQMGAQVELSFSGTAPIRIQGTKDLHSLEYRLPVSSAQVKSLVAFAALHADGQTRIIEPIRSRDHTELMLGLETIDQPNGERVIIVPGRKRIESKPFYIPADPSAACFIVALALLAKGSDIIIRDLCLNPTRTGYLAILAGAGAGISVENSRVIGGEAIGDVLVHSEGELNSLVISDPHEVANVIDEIPMLAVLSAFSSGRFELHHAAELRTKESDRIDALVVNLERLGFQCEQYPDGFKVNGRIAMPKGVVSIESFDDHRIAMSFAIAGKATGVDLAISDIGVVGVSFPNFFEIIESLEV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPA_ACTLI
Sequence: APKDDTWYTGAKLGWSQYHDT
What is the function of this protein?
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm.  Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
What are the official names of this protein?
Outer membrane protein A, Major outer membrane protein, MOMP.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.