PharMolix/UniProtQA huggingface dataset:
Protein: RL6_ACIET
Sequence: MSRVGKSPVSIPAGVDVSIKDDQISVKGAGGVLSLAQNALVKVSNNEGKLSFEPVNDSREANAMSGTVRQLVNNMVVGVSKGFEKKLTLIGVGFKAAASGNKLNLAIGFSHPVNFEMPTGITVATPTPTEIVIKGADRQVVGQLAAEIRAVRPPEPYKGKGIRYADEKVTIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PSBN_SAUCE
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ADA19_MOUSE
Sequence: MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRGKHPLRAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTVRDVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHSGPTSKDWALQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKRKLMEIANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLAQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQRVGAIISSKI
What is the function of this protein?
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.  Also cleaves alpha-2 macroglobulin.  May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, Meltrin-beta.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DAPB_BEUC1
Sequence: MTIRVAVLGAAGRMGSTTAQAVRDAEGLELVAEVDAGDDVAALAGRADVAVDFTLPDVTEANVHALLDAGIHAVVGTTGWDDDALGRVSDHVGRTAGLGVLVAPNFSLSAVLAMRFAAQAAPYFASAEVVELHHPRKVDAPSGTAVHTARGIADARGAAGSPPMPDATETALPGARGAVVDGVRVHALRLEGLVAHEEILLSNPGELMTIRTDTFDRASFMPGVLLAVREIADHPGLTVGLDAYLDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_ANOFW
Sequence: MKAGIHPNYKKVMVKCACGNEFESGSVKDEVRVEICSACHPFYTGRQKFASAAGRVDKFNKKYGLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL38_MACFA
Sequence: MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKEPK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ORYNI
Sequence: MEKFEGYSEKLKFPRQYFVYPLLFQEYIYVFAHDYGLNGSELVEIIGSNNKKFSSLLVKRLMIRMYQQNFWINLVNHPNQDRLLDYNNFFYSEFYSQILSEGFAIVVEIPFSLREQSCPEEKEIPKFQNLRSIHSIFPFLEDKFLHLHYLAHIEIPYPIHLDILLQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFILKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIIFSRKMEHFGLMYPAFFRKTIWFVMDPLMHYVRYQGKAILASKGTLLLKKKWKCYLVRLWQYSFSFWTQPQRIHLNQLENSCFDFLGYFSSVPINSLLVRNQMLENSFLIDTQMKKFDTKVPVTPLIGSLAKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYYSGSSKKKTLYRLKYILRLSCARTLARKHKSTVRAFMQWLGSVFLEEFFTEEEQVFSLMFAKTTYFSFRGSHSERIWYLDILRINDLVNPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM6_SHEON
Sequence: MSLPDATVVKAFLLDLQHRICAGLEQLDGQASFAADSWTRAEGGGGTSRVLTQGAVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPKNPYIPTTHANVRFFIAHKDGAEPVWWFGGGFDLTPYYPFEEDVREWHQSAKNLCQPFGDDVYPKYKKWCDEYFFLPHRNETRGVGGLFFDDLNQAGFDKSFDFMQAVGNGFLTAYAPIVERRKDTDYGERERDFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWQYAYTPAAGSPEADLYDNYLKPRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_RHIME
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRNEVIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSEEMVGHKFGEFAPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NUDC_YERE8
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGATARQIGEWQGQAVWLIRQMMSTDMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRYCGYCGHQMHASRTEWACLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMAEYDSGELRHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREEQFDDGE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: RS10_VIBPA
Sequence: MQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKKARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: AGO4_HUMAN
Sequence: MEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi).  Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them.  Lacks endonuclease activity and does not appear to cleave target mRNAs.  Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
What are the official names of this protein?
Protein argonaute-4, Argonaute4, hAgo4, Argonaute RISC catalytic component 4, Eukaryotic translation initiation factor 2C 4, eIF-2C 4, eIF2C 4.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: MNMA_ACAM1
Sequence: MKKVVVGLSGGVDSSVAAASLKEKGYEVIGLTLWLMQGKGQCCSDGLVDAAQLCEDLDIPHHVVDSRDLFSNNIIDYLVEGYQQGITPLPCSQCNKTVKFGPMLNYARHELDTDTIATGHYARIAYSEKEKRYQLLRAVDRNKDQSYFLYDLDQDLLSGTVFPLGDHTKTETRRMATQLDLHTAEKPESQDLCLIEAHGSMQTFLDQYIETHPGEIVDQEGNILGHHQGVHHFTIGQRRGIGVAAPHPLYVVDLDPGKNRVIVGDRETALKTECMVKRVNWVSIAPPQNPIHAEVQVRYRSKPTGVTIIPLDAEAPGGRVKLVFEDPQFGIAPGQAAVWYDQEILLGGGIIEAFS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRA_STRSV
Sequence: MSIGLVILVAVVALLLVVGYGTAVLMRKRNEALLQNLEERKEALYNLPVNDEVEEVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNNSFRFIKAKHAIGNIESQIDLIEEDIKMIRAALEDLKEQESKNSGRVLHALDLFEKLQTQVAENADSYGQALAEIEKQLENIQSEFSQFVTLNSSGDPVEAAEILDKAEDHILALTHIVEKVPAIVEELTVKLPDQLEDLESGHRKLLESGYHFIETDIESRFQQLHASLKRNEANISALELDNAEYENEQAQEEINALYEIFTREIEAHKVVEKLIKNLPSYLAHTKENNQQLQKEIERLSQTFLISDTETSHVKELQAELSAQEDVVLSAVEDSSETKQAYSVVQEELEAIQERLKEIEDEQISLGEALAEIEKDDANARQKVNIYANKLHTIKRYMEKRNLPGIPDSFLEIFFSTSNNIEELVKELEATRVNIESVNRWLEILGNDMEQLEEETYRIVQDATLTEQLLQYSNRYRSFDDNVQAAFNKSLYVFEHDYDYAQSLEIISKALDLVEPGVTERFVTSYEKTRENIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: RS9_SINFN
Sequence: MADLSALKEIATTAEPAAPVHVKKVDAQGRSYATGKRKDAVARVWVKAGSGKITVNGKPFSAYFARPVLQMILQQPIVAAARDGQFDVDATVAGGGLSGQAGAVRHGIAKALTYFEPGLRSVLKRGGFLTRDSRVVERKKYGRAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MUTL_STRA3
Sequence: MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISTAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIGADTVSEPIANFTNLDKSDGSVDNDVKNSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIIDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVESGIYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKMFKRIQENHTSLRDLGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SYP_SHESW
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWDKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGMMRSREFLMKDAYSFHLDVDTMNETYEAMYTAYSNILSRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPMPTEPRGAATEALRLVDTPNAKTIAELVEQFDLDITKTVKTLIVKGATEAAPLVALIVRGDHELNEVKADKLDLVASPLEMAPEALIRDAIGAGPGSLGPVGLNMPIIIDHSVSVMSDFAAGANVDDKHYFGINWERDLPLAQAADIRNVVEGEPTPDGLGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIVWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLSAAGIEVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDIPFDQLVDFLKNAVKS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_STRMK
Sequence: MRLTALPAFADNYIWTLIADDGTAVVVDPGDAAPVLALADQGLRVDTILLTHHHDDHIGGVPALQARFPGVRVIAPVEERIPTATGRVGEGERVQALGRTFHVLSVPGHTRSHIAFHTAEHLFSGDSLFSLGCGRLFEGTPSQLLASMRKLGTLPAQLLLCCAHEYTVSNAVFARHVDPANAALWQRQEEALAMRRDDRSTLPVTLANEFDCNPFLRVHAAPIRASVSAHLGRDVVDDVDVMAGLRHWKDGFRA
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PEPE_ECOSE
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARS_VOLCA
Sequence: MLQRLVVALCLLGFAALTAAAAHQRPNFVVIFTDDQDGIQNSTHPRYQPKLHEHIRYPGIELKNYFVTTPVCCPSRTNLWRGQFSHNTNFTDVLGPHGGYAKWKSLGIDKSYLPVWLQNLGYNTYYVGKFLVDYSVSNYQNVPAGWTDIDALVTPYTFDYNNPGFSRNGATPNIYPGFYSTDVIADKAVAQIKTAVAAGKPFYAQISPIAPHTSTQIYFDPVANATKTFFYPPIPAPRHWELFSDATLPEGTSHKNLYEADVSDKPAWIRALPLAQQNNRTYLEEVYRLRLRSLASVDELIDRVVATLQEAGVLDNTYLIYSADNGYHVGTHRFGAGKVTAYDEDLRVPFLIRGPGIRASHSDKPANSKVGLHVDFAPTILTLAGAGDQVGDKALDGTPLGLYANDDGNLLADYPRPANHRNQFQGEFWGGWSDEVLHHIPRYTNNSWKAVRVYDEDNQQAWKLIVSCTNERELYDLKTDPGELCNIYNKTRAAVRTRLEALLAVLVVCKGESCTNPWKILHPEGSVNSWNQSLDRKYDKYYANVAPFQYRTCLPYQDHNNEVSAFRSTVAAAAAAAAAAAAQQPGRRRMYTWTSAGRQLSATASAIATSPQPRSEPFVAEVERHSVPVPAEVLQSDVAKWFDNPLALA
What is the function of this protein?
Is commonly produced by soil microorganisms and plays an important role in the mineralization of sulfates.
What are the official names of this protein?
Arylsulfatase, AS, Aryl-sulfate sulphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DTDA_METAC
Sequence: MTDTNPENVNNSKITIICSAPDLASQNIKKHLLALREWKPLELPENSGFSAVLESADGKFRLVDIEEIHVFQDGLDKKLEAAGLPAELIIFASKHRSKEEVKSLTVHCTGNSSNEARLGGHPKELAVSSPPAMKSILMEMKRLAKVKGLDYDVTLEVTHHGPTELNVPSLYAEIGSTEGQWEEPVPGEIVARAILTVSLEKVPTAVGFGGGHYAMRQTGLLLETAISFGHNFPKYQLEFVDEALIRQAVEKSNAEFAYFDRKSMKSADRKRISQILEKLGLKVLKESEIREKYGREE
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: HIS1_BURP0
Sequence: MSAPLTLALSKGRIFEETVPLLAAAGVTVAEDPETSRKLILPTTDPNLRVIVVRATDVPTYVEYGAADFGVAGKDVLLEHGGGGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMPISSRLVVNQAALKLKRAALKPFLDAFERASLGSGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAN1_SCHPO
Sequence: MMRENPELLLGQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCGSLFYMSPECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQTDGTYRSYVHNPSTLLSILPISRELNSLLNRIFDRNPKTRITLPELSTLVSNCKNLTRRLRPAPLVSSRYLAYQQQQQQQQMNLQQGIQGYPHQGYMPTQNIGFPWPPTPQFVSNWNHCATPTIPVSLQVLTPNSSLKVDPTTPLTAPIHATESFWPSAAAAAAAVHNNANSYMPITPTPYPNNAKIFGYPNQPPLTPIPFTGFVLHPAPVGRAADAVDPSRKSL
What is the function of this protein?
This protein is a negative regulator of both sexual conjugation and meiosis.  It phosphorylates mei2.  It blocks the onset of meiosis until conjugation takes place.
What are the official names of this protein?
Negative regulator of sexual conjugation and meiosis.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: DAPB_CHLCV
Sequence: MRVGIIGCSGRMGTLLSNLLRATARFTLGPGFSRTSTHSLASVIDNNDVLVDFSSSSLSEELFRALLSNPKPLIFATTKPAPSSSIDEKIEDLAAYVPVVVCPNTSLGAYVQKRLAALLAAVFDDAYDIRITEVHHRGKKDAISGTANELVSILCDAKKKEWQQEYRVGADSDSVKNIELHASRVGNISGEHEIAFISDKEQITLRHTVFSREVFAEGVLRILDWLLNESPPPGCYGPEVGLKVSV
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_SALPB
Sequence: MYQPDFPTVPFRLGLYPVVDSVAWIERLLEAGVRTIQLRIKDKRDEEVEADVIAAIALGRRYNARLFINDYWRLAIKHRAYGVHLGQEDLETTDLKAIQAAGLRLGVSTHNDMEIDVALAAKPSYIALGHVFPTQTKQMPSAPQGLAQLASHIERLADYPTVAIGGISLERAPAVLATGVGSIAVVSAITQAADWREATAELLAIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MNMA_XANOM
Sequence: MSTPHIVVGVSGGVDSSVAAWKLAQQGEPIAGLFMQNWADDGSGDCRAEDDRRDAVAVCGVLGMPFHFRDFSGEYWSGVFEHFLAEYAAGRTPNPDVLCNREVKFKHFLDAAQALGAERIATGHYAQVAHRGRRWRLLRGADRDKDQSYFLHQLGQSQLAATLFPIGDLEKSTLRRIARDAGLPTHAKKDSTGICFIGERDFREFLGRYLPARTGEIRDPQGQRIAEHPGVFYFTLGQREGLNIGGVRGRAAAPWYVVGKDVASNVLYVDQDRDSPLLQSRWLQSEQAHWVTGAPPARRFSCTAQTRYRQPDEPCTVDVQDDGSVQVHFERPQRAVTPGQSLVLYDGKECLGGAVIAATDAPLERQLAGSSFSSEVVA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHO_TRIEI
Sequence: MAEIKKGSLVRVVREKLENSLEAKASDNRFPAYIFESQGEIVDTRGDYAFIKFGKVPTPNIWLRLDQLEKFE
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARNF_SERP5
Sequence: MRGYAWGAASVLLVTLAQLLMKWGMAQIPLMSFADVTLNLFMQYWLPLVVVSGGIFGYALSMLCWFFALHHLPLNRAYPLLSVSYALVYLAAVILPWFNESATLLKTLGTLFILFGVWLINSQAKVKTPQ
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.