PharMolix/UniProtQA huggingface dataset:
Protein: Y11K_STRFR
Sequence: MKATRRTRVASERGVRRRRRVRATRKAGELPVKVWARTLPSAAWDPVGSVRTQVTPSRAAPRTCQPPAWSSRRRGRPRSSRARSTEPAWSPEGVVRCAT
What are the official names of this protein?
Uncharacterized 11.4 kDa protein, ORF1.
Protein: CLPP_SALEP
Sequence: MSYSGERDNLAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMAHHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_DEIGD
Sequence: MVKIRLSRFGSTHNPHYRIVVTDSRRPRDGGYIENLGHYDPRKTTENYLKINAERAAYWLSVGAQPTQTARRLLKAQGVKVA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TACY_STREQ
Sequence: MKDMSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTLKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRSEYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYGSITYK
What is the function of this protein?
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes.  After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus.  Can be reversibly inactivated by oxidation.
What are the official names of this protein?
Streptolysin O, SLO, Thiol-activated cytolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Probably secreted as soluble protein by the accessory Sec system (By similarity). It then inserts into the host cell membrane and forms pores formed by transmembrane beta-strands (By similarity).
Protein: CDSA_CAEEL
Sequence: MSDQPPAENADVRQRRAPESPVTERLRAPARDDARPTSDESDMEGILQDEDSDAGSKNKEEKLERLTQAIPQDKGSLGVFADSMLEALPPRWRNWVVRGLFSIIMISTFTFIVTRGATWLMFLVFLIQFKCFQEIISIGLAVYRLYDFPWFRALSWYFLLTSNYFFFGESLIDYWGIVLKKDNFLHFLVAYHRLVSFALYCIGFVSFVLSLRKGYYMRQFSLFAWTHLTLLLIVSQSFFIIQNIFQGLIWFLAPVAMIICCDIMSYMFGFFWGKTPLIKLSPKKTWEGFIGGAFSTVVFGILLSLALYNRPFFVCPVQHYQTDSSNCTIPLAFQLQDYPVPRPFSFVYKILRKEPIIQLCPFVFHSIALSLFASILGPFGGFFASGFKRAFKIKDFGDVIPGHGGLMDRFDCQLLMGTFVMVYIHSFIRVPDASKLLKQIMTLEPQDQLNIFNLLQSELSKTGLI
What is the function of this protein?
Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns).
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECU_STRT2
Sequence: MVNYPHQISRKIAQVRTKKSNRVDFANRGMNFESAINATNDYYLSRGLAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYSGVYKGYYIDFEAKETRQKTSMPMKNFHAHQIKHMSQVINQDGICFVLLHFSTLKETYLLPAKDLIAFYQIDKGTKSMPLDYIKKRGYAIAESAYPQVPYLEIIEKLLGGNT
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDYB_SCHPO
Sequence: MSRNASNAYLKNGNSTPSNDKRSPSSLSQRSKTSTRSSKPFLQRLFPSTWFKNESSSRHPLTSIKENDTQTIGRRPSMRVKLFGKDKSKASMSTNDLPSHPRSQSVMGFSSSTSQLTGTSNSSRTRLNKDMRRDFGMTSMSSITSSTPTPSQLPVRPSTSLSFFDDIPLGPSFSAETILSSLSISTSNNAMSKTTPAPPLVTTKSISADQDDFYTCKEEVSTYEGLNSQIELSPVKSRDSQNKSAKNLSTAYRTVSGESRNLMVDPKVSPYGNSRTPLRDSSNYLRDRRSINRQSSLSIPKSTSETTRKTLALSNGGIDQSRVSSDSFKVDDSSAKMAAIDIWEGSQHIVSNDKALSWLVTDKPYNKAVLKHYISLYDFENTDILQSLRMICGNLYVHGETQELDHFLGEFSNQWCRTNPKGLFCNPQIVHSIAFSLLLLNTDLHIAELSASERMSRNQFVENTYRSIKQALNDSFDGNEEKKNAFFLSSYKSFASNESCNSPAIHSLHGNLSPGKSAELKKLHKRSLSSKVLEEAFSSYWMSALKEMYHSIKVSMILQPDRYLDMNFDFNDTNKINNPSSTANQTRHFHSVSEIKKLPMGTDELEKSMVRPSTAMYINRQNENAVSIDKSRDLQGTVNTKEIRSRSALSYQNDRPLATDLPSVIYNHKHPNVVSPFYVHPYIKQGILKFQSKESHKFRKKEVWSTVLAVLQRDVFTLYNLNTPNLSYDPKDLDISKVGKPVIKTTIIASLAKPFPSSEDAVVLKSTNSLYFDLETSSQLKLRFAGPSPKDAQGWIDALNYWAARSSKVPLLGGVTNVDYGWARCTGQRAQKSNAQLLKTKTDKIIVHKWQPQPVNTIPSSLSLGEQLSAFNNFMKLLKKTNDEHQNLHKEMLVVLSSQPKSTFRRAVENWKYKSDYLQLNLVRLRVYISVLEKYKSQAQNS
What are the official names of this protein?
PH and SEC7 domain-containing protein C11E3.11c.
Protein: XERC_RICAE
Sequence: MLDTSIQALINKWQKYLVLQRNYSNHTVISYNNDLKHFLEFMNYYNSELVTINHIKTADIRLIRSWLAKRNCDNFTASSISRGLSAVKNFYRFLEKTTQLNSHIIFSIKSPKKTKLLPKALSEDDVVISLEHIEEYGNVKWIELRNKALLVLIYASGLRISEALSITKLHLQNLEFIRIIGKGSKERIIPWLPIAKNLITQYLEILPYKLGDNEPIFRGKQGKKLQPPVFNRELIKLKHFYGLPQHLTAHSFRHSFASHLLEHGADLRSLQELLGHKSLSTTQSYTKTSIKHLEAVYTTAYPIKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDA_AERPE
Sequence: MAQQMPSPEEIAAQLQMIRDQIAELQGVLAQLELRLRSVQAAKETVEKAAGQDGETLFPGDPELNTILKARLLEPGKAIVHLGLNVYAKLDTAKATEILAKKEDALKRSLETLKQELDKLSRTHDQYLQLLQALTAGQAAQQAGQQQKQGS
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPB2_CAEJA
Sequence: MSKSRRVFLSMQDDDDFWGNGDRFEEEKSCLAAKAKQRSCPVVEMEEDDEEMEEKYFFKQSHLVRQRLEQMKEREKVDEEKEGVERREENGFSGKPWKFRVDSDEHEMKSDDVVTEDRSIMGTKTFNSDFDDKSAIKSSLSMSLESNDVFYANYRNFFRGRPEVHFLIRCLFEKNPETFDNQFIDLYEKTRKRLEMYPNPHINQILRRTLSSSNATETRVRSKHAVVVSNFREPDRRLGRYSKYYYHHNVGPEVYSRKVFVGGLPACVTEDDILGFFSRYGRLQVDWPSKHYGGSKSDSDPSLCSEIITPPAPLSHLSMASPPFGQINPFMSGYVAPAETRGGFLRASGFSEGGGFGGGFGGGIGGGGGFNSGSGSGNGTKSDGSTSEKRQSHLGYVFLLFEKERSVRDLVAECFEEEEGLFITLESSLEPIRVQIRPWLLADAEFLMDFNVPINTKLVAFIGGVPRPLKAVELAHFFEQTYGNVVCVGIDIDNKFKYPRGSGRVAFSNYDAYVQAITDRYIVLDHEDIHKRVEIKPYFFHNQSCEECSGRYHRQHAPFFCPSLECFQYYCEPCWHKMHAHPSRFHHMPVVKGV
What is the function of this protein?
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 2.
Protein: HUTI_ACIB5
Sequence: MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTPGFIDCHTHSVFGGNRSVEFEKRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKRIRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLPMTVKSTCLAAHALPPEYKDQSDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQLSSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLIKHGVRIALSSDLNPGTSPALSLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGSLEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVIF
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_GEOTN
Sequence: MGQKVNPIGLRIGIIRDWESRWYAEKDYADLLHEDLKVREYINKRLQDAAVSRVEIERAANRVNVTIHTAKPGMVIGKGGSEVEALRKALAQLTGKRVHINIVEIKKPDLDAKLVAENIARQLENRVSFRRAQKQAIQRAMRAGAKGIKTMVSGRLGGADIARSEHYSEGTVPLHTLRADIDYATAEADTTYGKIGVKVWIYRGEVLPTKKKAEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GLPE_ECO8A
Sequence: MDLFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRK2_RAT
Sequence: MSPWPRWHGPAMARLWGLCLLVLGFWRASLACPMSCKCSTTRIWCTEPSPGIVAFPRLEPNSIDPENITEILIANQKRLEIINEDDVEAYVGLKNLTIVDSGLKFVAYKAFLKNGNLRHINFTRNKLTSLSRRHFRHLDLSDLILTGNPFTCSCDIMWLKTLQETKSSPDTQDLYCLNESSKNTPLANLQIPNCGLPSARLAAPNLTVEEGKSVTISCSVGGDPLPTLYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVRGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLMAKNEYGKDERQISAHFMGRPGVDYETNPNYPEVLYEDWTTPTDIGDTTNKSNEIPSTDVADQTNREHLSVYAVVVIASVVGFCLLVMLLLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIHTLLQNLAKASPVYLDILG
What is the function of this protein?
Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.  Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4.  Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2.  Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation.  Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades.  Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth.  Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival.  Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity.  Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation.  PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival.  Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions.  May also play a role in neutrophin-dependent calcium signaling in glial cells.
What are the official names of this protein?
BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Trk-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Early endosome membrane. Cell projection, axon. Cell projection, dendrite. Cytoplasm, perinuclear region. Postsynaptic density. Note=Internalized to endosomes upon ligand-binding.
Protein: ARNA_SHIB3
Sequence: MVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPSAFSYVGNQKFTVWSSRVHPHASKAQPGSVISIAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGKMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).
What are the official names of this protein?
Putative bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: FDB41_GIBM7
Sequence: MGVQSTANLPKETVSHLDTAPTPKPGVLLQVRAGRIKKGALGGEITSAIYKQQHDGPVFCSATGVLGDEHASSGHGGTERAVHQYNPDHYPDWRAENPPEPDLYDVGAYGENLVTTNMSDENVCIGDIYKLGDDVLLEVSEPRHPCFKLNSRFKWPRALKRTIRTGRAGWNMRVLKTGNICKGDTISLLERPYPKWSVLNVQRVIRARNVSLNLLAECTQLPMTDLFLDIAKERLRSAPKTYTLVDAHLVAQRVRKLTFALKEPLTIVNPAFDPYAFAQVTFGRETKFERSYSIVDGDIYKFSLGVSLDRQSRGGSAYLHNELKIGDQIEMSPGSNPGAMENDAKCDESLTRVLIVGGIGITAFLPSMRDWESKGLPYHLHYAIRSLEEAAFLDQLPKDKTTLYIRSEGQRLDISGAIPKPNHDGAYNARIFSCGPSGMMKECETVAKELGYPDHMLHFEDFGSGGGGDLGEPFEVEVDEPDSNRHETMTVPPNKTLLDVLNDAGFDVLYSCKSGACGACKVELCEGKVDYKSTALLGKEKGKALQACVDRGIGRLRIEID
What is the function of this protein?
Reductase; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
Reductase FVEG_12641, Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12641, FDB2 cluster protein FVEG_12641.
What is the protein family that this protein belongs to?
Belongs to the PDR/VanB family.
Protein: LIPA_SHEB5
Sequence: MNRPERLQPGVKLRDADKVSRIPVKIVPSERDTMLRKPDWLRVKLPASNQRILEIKQALRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPVKLAQTIRDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLNPDIKIETLVPDFRGRIDAALDILSTEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKRFKERHPNVPTKSGLMMGLGETNEEIAQVLRDLRAHNVEMLTLGQYLQPSKFHLPVERYVPPAEFDELKALADELGFTHAACGPLVRSSYHADLQAQGKEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBCMT_ARATH
Sequence: MSASVAVVSGFLRIPSIQKSQNPSFLFSRPKKSLVRPISASSSELPENVRNFWKWLRDQGVVSGKSVAEPAVVPEGLGLVARRDIGRNEVVLEIPKRLWINPETVTASKIGPLCGGLKPWVSVALFLIREKYEEESSWRVYLDMLPQSTDSTVFWSEEELAELKGTQLLSTTLGVKEYVENEFLKLEQEILLPNKDLFSSRITLDDFIWAFGILKSRAFSRLRGQNLVLIPLADLINHNPAIKTEDYAYEIKGAGLFSRDLLFSLKSPVYVKAGEQVYIQYDLNKSNAELALDYGFVESNPKRNSYTLTIEIPESDPFFGDKLDIAESNKMGETGYFDIVDGQTLPAGMLQYLRLVALGGPDAFLLESIFNNTIWGHLELPVSRTNEELICRVVRDACKSALSGFDTTIEEDEKLLDKGKLEPRLEMALKIRIGEKRVLQQIDQIFKDRELELDILEYYQERRLKDLGLVGEQGDIIFWETK
What is the function of this protein?
Protein-lysine methyltransferase methylating chloroplastic fructose 1,6-bisphosphate aldolases.  Can also use with low efficiency gamma-tocopherol methyltransferase as substrate, but not a cytosolic aldolase.  Able to interact with unmethylated Rubisco, but unlike in pea, the complex is catalytically unproductive.
What are the official names of this protein?
[Fructose-bisphosphate aldolase]-lysine N-methyltransferase, chloroplastic, Aldolases N-methyltransferase, [Ribulose-bisphosphate carboxylase]-lysine N-methyltransferase-like, AtLSMT-L, LSMT-like enzyme.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Plant protein-lysine LSMT methyltransferase family.
Protein: ATPO_RAT
Sequence: MAAPATSVLSRQVRSFSTSVVRPFSKLVRPPVQVYGIEGRYATALYSAASKQKRLDQVEKELLRVGQLLKDPKVSLAVLNPYIKRSIKVKSLKDITTKEKFSPLTANLMNLLAENGRLGNTQGVISAFSTIMSVHRGEVPCTVTTAFPLDEAVLSELKTVLNSFLSKGQILNLEVKTDPSIMGGMIVRIGEKYVDMSAKSKIQKLSKAMRDLL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase subunit O, mitochondrial, ATP synthase peripheral stalk subunit OSCP, Oligomycin sensitivity conferral protein, OSCP, Sperm flagella protein 4.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: OZF_HUMAN
Sequence: MSHLSQQRIYSGENPFACKVCGKVFSHKSNLTEHEHFHTREKPFECNECGKAFSQKQYVIKHQNTHTGEKLFECNECGKSFSQKENLLTHQKIHTGEKPFECKDCGKAFIQKSNLIRHQRTHTGEKPFVCKECGKTFSGKSNLTEHEKIHIGEKPFKCSECGTAFGQKKYLIKHQNIHTGEKPYECNECGKAFSQRTSLIVHVRIHSGDKPYECNVCGKAFSQSSSLTVHVRSHTGEKPYGCNECGKAFSQFSTLALHLRIHTGKKPYQCSECGKAFSQKSHHIRHQKIHTH
What are the official names of this protein?
Zinc finger protein OZF, Only zinc finger protein, Zinc finger protein 146.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IOJAP_SYNY3
Sequence: MTEISRFDAYPPTLTVNPIVPADAPATEHLVWTIAQAAEERKAGDLVILKVTDVSYLADYFVICTGFSRTQVRAIADNIEKQVELVHGQLPTHTEGNSESIWVLQDFGDVLVHTFMPEEREFYKLEAFWGHAQEQTLADIATAIGVAYNAPTSP
What is the function of this protein?
Functions as a ribosomal silencing factor.  Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8.  Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity).
What are the official names of this protein?
Ribosomal silencing factor RsfS.
What is the protein family that this protein belongs to?
Belongs to the Iojap/RsfS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_STAA9
Sequence: MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPILCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGFYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y066_TREPA
Sequence: MQRVLESDTPYFVKGIQRPVSTLSDRDRALLNRRGNAYLNEGKLQEAARVFITTGYHDGLTRIGDVYMRKADVLTALRFYYFARNEQKMRPIVSALSVLIRCLI
What are the official names of this protein?
Uncharacterized protein TP_0066.
Protein: CPSY_MYCBO
Sequence: MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRKVLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTIDEPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVYEETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVVFDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYALRSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYNSHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKTRIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLIEMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVLYVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLERYFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA
What are the official names of this protein?
Exopolysaccharide phosphotransferase CpsY, Stealth protein CpsY.
What is the protein family that this protein belongs to?
Belongs to the stealth family.