PharMolix/UniProtQA huggingface dataset:
Protein: PORCN_DROME
Sequence: MDYQYFEEESDYIDLDEEEEDDDVVTAGSLDHRFGQPNGEEDYYFGGDDVEEELVVDGHGVLELAGRLLESLQSCVQPSVLQVMQYVAPMLLLCLLCRLLCLLYSQRRRLTSLAPLHLFHFACGLIILQITVGYRLLLLLLLAAVGYLLLQLLRLGRRGAQVLAVLTVGSQFLYELLIWRRRSDWPQLRGIQMVVNMKLISLGFDLTASGQLQARIPGPFAYLGYIYSPATCALGPWVSFGCYMDCLVPRNSWLVSLRRLLPNVVICVLAVTVSNCVAPALSDFFGDSSHFLVMYWDALSVRSSHYFVGMMAQALLVASDQRLDGATKESDMLGPLISQPWRIEWPRSISSLVRSWNIPMHEWLKRYIYAPCKPTASTSRGRILVVVLSTYLVSSLLHGMDLRIYLVLISLAFLAEGESLLRRQLASLLNACITANLCPGKERCRYSHCPSKRRLNSLSYWLARLTNLAFTALAIFHLAYLGVVLLGDDLEVGEDGDSFLWHWQQAGYLSHYIGLGTFVLYLFIS
What is the function of this protein?
Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins.  Serine palmitoleoylation of Wnt proteins is required for efficient binding to frizzled receptors (By similarity).  Also facilitates the glycosylation of Wnt family members, including wg and Wnt5.  The cotranslational disulfide bond formation of wg competes with the N-glycosylation.  Porc stimulates the post-translational N-glycosylation by anchoring wg at the ER membrane, probably through acylation (PubMed:11821428, PubMed:15166250, PubMed:22108505, PubMed:8985181).
What are the official names of this protein?
Protein-serine O-palmitoleoyltransferase porcupine.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Porcupine subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HBHA_MYCTU
Sequence: MAENSNIDDIKAPLLAALGAADLALATVNELITNLRERAEETRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELRKAAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPKKAAPAKKAAPAKKAAPAKKAAAKKAPAKKAAAKKVTQK
What is the function of this protein?
Required for extrapulmonary dissemination.  Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells; binds heparin, dextran sulfate, fucoidan and chondroitin sulfate.  Promotes hemagglutination of erythrocytes of certain host species.  Induces mycobacterial aggregation.
What are the official names of this protein?
Heparin-binding hemagglutinin, Adhesin.
What is the protein family that this protein belongs to?
To M.leprae HbhA.
What are the subcellular locations of this protein?
Cell surface.
Protein: ROBO4_HUMAN
Sequence: MGSGGDSLLGGRGSLPLLLLLIMGGMAQDSPPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAEKSDEGTYMCVATNSAGHRESRAARVSIQEPQDYTEPVELLAVRIQLENVTLLNPDPAEGPKPRPAVWLSWKVSGPAAPAQSYTALFRTQTAPGGQGAPWAEELLAGWQSAELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGTVFVSWVPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATHMPGSYCVQVAAVTGAGAGEPSRPVCLLLEQAMERATQEPSEHGPWTLEQLRATLKRPEVIATCGVALWLLLLGTAVCIHRRRRARVHLGPGLYRYTSEDAILKHRMDHSDSQWLADTWRSTSGSRDLSSSSSLSSRLGADARDPLDCRRSLLSWDSRSPGVPLLPDTSTFYGSLIAELPSSTPARPSPQVPAVRRLPPQLAQLSSPCSSSDSLCSRRGLSSPRLSLAPAEAWKAKKKQELQHANSSPLLRGSHSLELRACELGNRGSKNLSQSPGAVPQALVAWRALGPKLLSSSNELVTRHLPPAPLFPHETPPTQSQQTQPPVAPQAPSSILLPAAPIPILSPCSPPSPQASSLSGPSPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSEGEETPRNSVSPMPRAPSPPTTYGYISVPTASEFTDMGRTGGGVGPKGGVLLCPPRPCLTPTPSEGSLANGWGSASEDNAASARASLVSSSDGSFLADAHFARALAVAVDSFGFGLEPREADCVFIDASSPPSPRDEIFLTPNLSLPLWEWRPDWLEDMEVSHTQRLGRGMPPWPPDSQISSQRSQLHCRMPKAGASPVDYS
What is the function of this protein?
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning.  May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).  Involved in the maintenance of endothelial barrier organization and function (PubMed:30455415).
What are the official names of this protein?
Roundabout homolog 4, Magic roundabout.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ROBO family.
Protein: RSGA_PHYMT
Sequence: MKKALVIKFFMGNYLISDIETKDKITAQVKGKLKNYDTHKKELFIIKVGDIVIYENYLDRYLISEVLERHNELNRPNIANFNQVILVFSLYKPRFQFRLLDKFLLILNKYKLKIILIFTKIDLITKKKFLIIQKKISYYENFYRIYYVNSKNKNSTHHLMDIFSNKITVLAGQTGVGKSTFLNSLKPSLQLKTQEISKKLGLGKHTTKNAQLYEFNGGYIADTPGFSKLDLTIFDYEELKFFYPDFLLYSDKCYFKKDCSHIKEINCGVKKALKLSLIPDWRYDNYLKFIEKIQEQKKLNYNKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_AROAE
Sequence: MRSPAPSLPDIIAALATAPGRGGIGVVRVSGAALAPFARALTGREPKPRHAAFTHFVDAVGKPIDEGILLYFPAPHSFTGEDVIELQGHGGPVVLQLVLARCLELGARLAEPGEFSRRAFLNGKMDLAQAEAVADLIEASTVVAARSAVRSLSGVFSDEMHRLTDALIDLRMLVEATLDFPDEDVEFLENARALERLDAIRVKLERVLERARQGALLRSGMNVVLVGQPNVGKSSLLNCLAGDERAIVTDIAGTTRDAVRETIAIEGIPIHVIDTAGLRETADPVERLGVERTWREIARADVILRIVDARVGPQPGDDAIDAALPEGVERITIFNKIDLCGLEPARLQHDDGVVIQLSAQLALGVDLLRSELLRVAGWHAHGDDVVLARERHLVALRDALTHVVAARSQCGALELFAEELRLAQIRIGEITGEFSSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STAAR
Sequence: MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDTTHITNIIKEWLNLSVNVERISVND
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RECF_MYCMM
Sequence: MYVRHLGLRDFRSWAHADLELGPGRTVFVGPNGFGKTNIIEALWYSATLGSHRVGTDAPLIRAGADRAVISTIVVNDGRECAVDLEIAAGRANKARLNRSPVRSTREVIGVLRAVLFAPEDLALVRGDPADRRRYLDDLATLRRPTIAGVRADYDKVLRQRTALLKSVSGARFRGDRGALDTLDVWDSRLAQHGAELMAARIDLVRLLAPEVEKAYQLLAPESRSAAIAYRASMDAFVAADDAAPDRVTLEEGLLAALAARRDAELERGVCLVGPHRDDLELRLGDQPAKGFASHGESWSMAVALRLAAFALLRADGSEPVLLLDDVFAELDAARRTALARVAESAEQVLVTAAVLEDIPSGWDARKVHIDLRDSADGRVSVVQS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIKI1_DANRE
Sequence: MTMMTMMMVSWSAFLQICWILMVRANQFNPGEPSGCRTNTPQSDLNSFLWTIKRDPPSYLYGTIHVPYTRVWDFIPQNSKQAFQESSVVYFELELTDPSTISALSRCQLLPAGQNLQDVLPPELYLRLKTHLEYVRLMLPSWMTPDQRGKGLYAEYLFNAIAGNWERKRPVWVMLMVNSLTEADIKTRGVPVLDLYLAQEAERMKKQTGAVEKVEEQCSPLNTLDFSQVIFALNQTLLQQESVRAGSLQVPYTTEHLITHYNCGDLHSIISHDTAQVPNFNNVTLRPSDQVTAQQIDSYFRRELIYKRNERMGRRVTALLQEQPHKTFFFAFGAGHFLGNNSVIDVLRREGYEVEHTPAGQPLHRRSGWRSADPADTDAALQPFLHHSRHHELQLLEGLELLEKVEHKLKKKHRRNKLKKQRQFNDLWVRMEDSVTAEAPPPLIHIINGYITVQTHPQEHERANHDRTFSGSSSRTGPALSALAVCVQMLRLLL
What is the function of this protein?
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins.  Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation (By similarity).
What are the official names of this protein?
Metalloprotease TIKI1, TRAB domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the TIKI family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GGNB2_XENLA
Sequence: MARLVAVVKYSDEDYPFEKRQMPLYIDDSLTMVLEFSDNMLNLDKQQIDTVQLEQFIQHHKMLTEQDLTAALTVTSREVFNALSQLLPCVGCRRCVERLFSQVMQTGIQALDPLSVGANGVLTLSHSFMTDATKLYTLFYVCGSKLNSMIDTIAKNKKGKKNNRCKFHSLDVRKPKPLGGHWMDVWEVMSPECRDEVALIDSNCLLETLENYLQKHRFCADCKNKVHRAFNILTGELDFSKVKGYCANVYQGLRCCPHEGHIHLCCETDFIAHVLGRAEPEFAGGYERRERHAKTIDVAQEEVLTCLGIHLYERLHRIWLKLRAEVQTRQMLFYLGVDALRKSFEVTVEKVQGISRMDQYFKDILEEEKVQELKQEKKRQKKNRRKNKTSCDLPAPHETKSANASQNNDPPGFMESGGDSCNTSEDRNMCAEVTVKNEDLLRSHKMKKGLTPHSNVSDCGYSSSLEGSEPGSQEGSDVACAEGICKHDEAGDDEKDEEEGDSCVECWNNCTKDNIKGKSKKKKKKCKPFKCENENTLKQVPYNTESSDVHSNPNEENKVFNFCMDSEFPRRPWIYHRNEFFSDMSSSESQMRETKSLKELLDESECSSQEEDEITQDDIQAFKETYQTFYRDRQQFRQCLKENFKQFCLHRNPSLLVGKTGAIN
What is the function of this protein?
May be involved in spermatogenesis.
What are the official names of this protein?
Gametogenetin-binding protein 2, Protein ZNF403.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PI15_MOUSE
Sequence: MIMNSAVSLVILLSLLCEAHTVVLLNPTDSSLPANNFTDTEAALSTPLESADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGACTDNLCFPGVTTNYLYWFK
What is the function of this protein?
Serine protease inhibitor which displays weak inhibitory activity against trypsin (By similarity).  May play a role in facial patterning during embryonic development (By similarity).
What are the official names of this protein?
Peptidase inhibitor 15, PI-15, SugarCrisp.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBEY_ERYLH
Sequence: MKLEIEIEHWPDGEWESITGGAAKATRDVEPALAHARLETSVLFTSDEQVHVLNREWRERDKPTNVLSFPMLDRDRLRALEPEGPPEMLGDIALAYETCAREAEEKGISLEAHATHLIVHGLLHLAGHDHVDSDAQAEEMEALEIAALAKLGIADPYGDRT
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_YERPE
Sequence: MSTIEERVKKIIVEQLGVKEDEVKNSASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFINANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSPU_SHIFL
Sequence: MIRQQKRLTIILLLLGVDKRDYSSCNVKTLLYSIRDYAKSVNDHEILTESNRLLSHCISDSNGAFFKSSKYVPLKYLRKRRIARKIPND
What are the official names of this protein?
Uncharacterized 10.4 kDa protein in spaT 3'region, SPA-ORF11, ORF-11.
Protein: PBCA_EMENI
Sequence: MTCADVTDLCTQASQLVQQLRTKDGELGFMSAAVYDTAWVSMVQKTTPEGRQWLLPKCFEYILRTQLEDGSWETYASDVDGILNTAASLLALETHAESRIASTDPPVEEMKERIGRARAALSRQLQAWSVKDTVHVGFEIILPALLRLLREKGHEFEFDGRAELDRLNRIKLSKFRPEYLYSARTTALHSLEAFVGMIDFDKVAHQKVNGSFMFSPSSTAAFLMFSSSWDDECEQYLRLVLQNGAGGGTGGMPSAYPSKYFEVSWVRGQLARLESKLTELQALTTLLDNGYSTGDLGIEDTDSLGEMLRDALVKGGGIVGFAPSIQADADDTAKSLIAVSLLDKPVSAQGLIDAFEGPMHFRTYHGERDPSFTANSNVLLALLNTPDAATVSPQIEKAAAFLCDVWWTADSEIGDKWNLSPYYPSMLMAEAFGKLLQVWSDGGLKSISSQFIRDRVSVCLYQALVRTLQTQNENGSWGSHSHEETAYAILTIAHACQLPVVNQLWTNVQLAVSRGRKFLQNSAGDKAEYLWVEKVTYSSILLSKSYVLAALKVSFERSYPACLANLFIVSKKRVIEFARFHSMLPLFSSMELWKVRAAIVEGYLLLPQLRDRRLAVFSRTGMEEDKYFEYIPFTWTLCNNRRNTFLSTKTLVEMMVISFLNYQADEFMEAVVGRLNSSQRSMTRSCIDEIFRDLKDKPELNDAIQAQSGPRNADANGHRILPQAKRIKMGSQLPSDVSRVLSAFVHHVMDHPSVKAAAPLEYERVKNELQVFLLSHIEQADDNGRFAAQLESTRDDFETARSSFYRWVSSTSSDHTSCPYSFAFYQCLLGFEQASHNAACFQTCEEKYVAEAMCRHLAVMCRMYNDYGSLARDRDEKNLNCVNFPEFAQAGPKSDAVRQKQLFSLAEFERSNMKRGLEVLTEMAAQDRAKMRMLEKVQMFCDVTDVYGQIYALEILRVGCDLAHDCFMLELPAQWSNST
What is the function of this protein?
Bifunctional terpene synthase; part of the gene cluster that mediates the biosynthesis of the diterpene ent-pimara-8(14),15-diene (PD) (PubMed:22506079, PubMed:27098256).  Within the cluster, the HMG-CoA reductase AN1593 functions in the mevalonate pathway, which produces isoprenoid precursors (PubMed:22506079, PubMed:27098256).  The geranylgeranyl pyrophosphate (GGPP) synthase AN1592 is needed in the formation of GGPP, the precursor for diterpenes (PubMed:22506079, PubMed:27098256).  Lastly, the pimaradiene synthase pbcA performs the 2 cyclization steps that convert GGPP to ent-pimara-8(14),15-diene (PubMed:22506079, PubMed:27098256).  The putative roles of the remaining cluster enzymes in ent-pimara-8(14),15-diene biosynthesis is unclear (Probable).  The cytochrome P450 monooxygenase AN1598, the glutathione S-transferase AN1595, the oxidoreductases AN1596 and AN1597 probably function as decorative enzymes (Probable).  It is possible that in biological conditions the compound is oxidized to ent-pimara-8(14),15-dien-19-oic acid, which is a bioactive diterpene compound predominant in many plant extracts (Probable).
What are the official names of this protein?
Pimaradiene synthase pbcA, Bifunctional terpene synthase pbcA, Pimaradiene biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: IFNG_BOSIN
Sequence: MKYTSYFLALLLCVLLGFSGSYGQGQFFREIENLKEYFNASSPDVAKGGPLFSEILKNWKDESDKKIIQSQIVSFYFKLFENLKDNQVIQRSMDIIKQDMFQKFLNGSSEKPEDFKKLIQIPVDDLQIQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRASM
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERA_BUCCC
Sequence: MQKKTFFGKIIIVGRTNVGKSTLLNKLIKSNISIISRKPNTTQKHIIGIYTYKLFQFEIFDSPGLQDKYHNIIEKKKIRDTFNLINESDIIIFLITNFIWKNIEIKILNFIQKKKKKYIIVINKIDLITEKKKLLPFILKISKFAPNSEIILISAKKKKFLDILLTNIKKKLPIANHKYISTKKTIYKEKFLITEIIRKTLMHLLYKELVYSFIISDVILNKNIKNKYIIFCIIIVNNKRHKKIIIGKHGEKIQKCILYSIKKIEKTFKKKTLLKIKIKIKKNKFKKEENGNYRNWN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: HPRK_BORPA
Sequence: MLTVQELVDDNADKIPFSWIAGHDAADRAIPDDGMAAADLVGHLNLIHPSRIQVFGQEELAYYTRFDLRRRMHHMDELLIGGVPAILLADGLTPPQDLIDQCAQHQVPLLSTPVAAAQLIDLLRIYLGKKLAPTTTVHGVFLDVLGLGVLITGESGLGKSELALELISRGHGLVADDAVELSRTAPGVIEGHCPQLLQNLLEVRGLGLLDIRTIFGETSVRRKMRLKLIVHLVRATAQDKFERLPLQDITQDMLGLPIRKVMLQVAAGRNLAVLVEAAVRNTILKLRGIDTLGEFMERQAMAILQSSK
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: HIS8_GEOSW
Sequence: MEIKTQLRGLPPYQPGKSIEEVKREYGLTDIIKLASNENPYGCSPAVKEAVMKQLDHLAIYPDGYARLLREKVATHLGVNETQLIFGNGSDEVVQIICRAFLSPNTNTVMAAPTFPQYRHNAVIEGAEIREIPLVDGRHDLEAMLNAIDEQTRVVWICNPNNPTGTYVNEQELTSFLERVPSHVLAVLDEAYYEYATANDYPQTVPLLRQYDNLMILRTFSKAYGLAALRVGYGIASETLIREIEPAREPFNTSSVAQAAAIAALDDQAFIRECVEKNKQGLETFYRFCEENGLRYYPSQANFILIDFGIEGNEVFQYLLERGIIVRSGNALGFPTSVRITVGSKEQNERIIHALTQMLKEKQLI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: VOGR_BPP2
Sequence: MFHCPLCQHAAHARTSRYITDTTKERYHQCQNVNCSATFITYESVQRYIVKPGEVHAVRPHPLPSGQQIMWM
What is the function of this protein?
This protein may act as an activator of P2 late transcription through an interaction with the alpha-subunit of the host RNA polymerase.
What are the official names of this protein?
Late control protein ogr.
Protein: CYB_ELIEL
Sequence: MTNIRKSHPLLKIINHSFIDLPAPSNISSWWNFGSLLGICLILQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGMYYGSYMSIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIVALVMVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDILGVLLLLLFLISLVLFTPDLLGDPDNYTPANPLNTPPHIXPEWYFLFAYAILRSIPNKLGGVLALILSILVLALLPHLHTSKLQSLMFRPLTQTLYWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFAIILIFMPMAGMIEDNVLKMD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SUCC_BRUAB
Sequence: MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIVELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DER_XANP2
Sequence: MTFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGLEEADAASLEGRMRAQTEAAIGHADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANKSEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAICDALPEQTRPEPEEDEDADTDFVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAGAKLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLVAREGRALVIGYNKSDLVARGGLITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAISSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLRYMTQPKARPPSFVLFCSRTDAVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PETG_CITSI
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CW15A_XENLA
Sequence: MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQATQDAPEEVRSRDFRRELEERERVVARDKNRDRPTREHTSSVSKKPRLDQIPAANLDADDPLTDEDGDEDSDEDSDDDTAALLAELEKIKKERAEEKDRKELEQKAEEERIRMENILSGNPLLNLTGPAAQSQASFKVKRRWDDDVVFKNCAKGVDEMKKQKRFVNDTLRSEFHKKFMEKYIK
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Protein CWC15 homolog A.
What is the protein family that this protein belongs to?
Belongs to the CWC15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBB_BRUME
Sequence: MKGFMIAAPASGSGKTTVTLGLLRALKRRGEVLAPVKAGPDYIDPAYHRAASGVDCFNLDPWAMRPELISALSSRMTESGARVLVAEGMMGLFDGAIDGKGSSADLARLLDLPVVLVVDCARQSHSIAALVWGFSQFRKDVLIEGVILNRVGSPRHEAMLRGALAPLGVPVLGALPRDPALSLPERHLGLVQADEHAGLESFLEQAADVMEAHIDMDALQTIWLRPKRYDAMANVARLKPLGNRIAVARDDAFAFAYMHLFEGWRRRGAEISFFSPLADEAPKADADAIYLPGGYPELHAQRLAGASRFRTAIGDAAARGVTVYGECGGYMVLGKTLEDAAGVHHPMLGLLPLETSFARRKLHLGYRLLEPLGGLPWDMPLKAHEFHYASIVREEKADRLFRVRDASGENLGEAGLRVGSVSGSFMHVIDFSGEAA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Hydrogenobyrinate a,c-diamide synthase, Hydrogenobyrinic acid a,c-diamide synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.