PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_SYNR3
Sequence: MSSSFHHQPVLPQQVLEALAELPDEGVLLDATVGGGGHSSLLLDVHPGWQLIGLDQDPAARAAAAQQLERFGERVQLVASNFAAYTPDQPVVAVLADLGVSSHQLDVPERGFSFRADGPLDMRMNTEGDGETAAALIDRLEENALADLLFHYGEERLSRRIARRLKTEGPWDDGERGTAALAYAIAGCYPPKQRHGRIHAATRSFQALRIAVNDELGVLETLLNDAPNWLEPGGRIAVISFHSLEDRLVKNRFKADERLRVISRKPLIASEQEAEANPRARSAKLRVAERLSAELEPAQ
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_THEVB
Sequence: MKTLPKERRYETFSYLPPLSDAQIARQIQYAIDQGYHPCVEFNETSNAEIRYWTMWKLPLFNCTNAQDVLNEVQQCRSEYPNCFIRVVAFDNIKQCQVMSFIVYKPNQANSGYSGYRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: MENG_SYNE7
Sequence: MSVLAPDAVEGLFDQIAPIYDNLNDQLSFGLHRLWKRMAVKWSAAKPGDRVLDLCCGSGDLAFLLAKVVGSKGQVIGFDRSQALLSVAGDRARQLASALVIDWQRGDALDLPFPDDHFDAATLGYGLRNVPDIPTVLRQLQRVLKPGARAAILDMHRPYSPLLRQFQQVYLDRWVVPAAAAQNCAAEYEYIDASLEAFPQGQQQVALAIAAGFQRAKHYELAAGLMGVLVVEA
What is the function of this protein?
Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.
What are the official names of this protein?
2-phytyl-1,4-naphtoquinone methyltransferase, Demethylphylloquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SCR2_ORBFA
Sequence: MAVKFHLCLLLIILVGMGAHVAFADQQFCDHPYGTCYYVEDECPEDMPVDCSENFYCTEPTNKCCCYE
What is the function of this protein?
Induces neurotoxic symptoms on zebrafish (By similarity).  Has also been claimed to be implied in calcification, but tests on homolog proteins suggest that proteins of this family have a neurotoxic function and not a calcification function (PubMed:19283069).
What are the official names of this protein?
Small cysteine-rich protein 2, Mfav-SCRiP2, SCRiP2.
What is the protein family that this protein belongs to?
Belongs to the Cnidaria small cysteine-rich protein (SCRiP) family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: Y0176_EMENI
Sequence: MGDGMRRLSRAHRCRIGCFEPGLRVRMVGISSLKDIDGAVVLNSDKHLDPHWRRQEPRMA
What are the official names of this protein?
Putative uncharacterized protein AN10176.
Protein: TANT_DROME
Sequence: MDNIVYDFAKITFQAKDNRSPTTNSNLSWQLNQMALSDMEEMQDTSEPIAPPESDDNVSSESHDSDDVDSQLSRCEDNDDDSDCISGSSRRSSTFGARAGVARRRMPARVSKDNFNRICSAIMKPIKKKQRKELNTNAQTLKSIEKIYTSRRMKKFTPTNLETIFEEPSDENAADAEDDSEECSISSQVKVVKVWGRKLRRAISFSDGLNKNKILSKRRRQKVKKTFGKRFALKKISMTEFHDRLNKSFDSAMLEGDDAEAGGSAEAVNIPKTSMTMEDIQLPTMSSQHQFLMQPAGFE
What is the function of this protein?
Potential cofactor involved in sensory organ development.  Despite its interaction with the Polycomb group protein Asx, it does not regulate the expression of homeotic genes.
What are the official names of this protein?
Protein tantalus.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In embryos, it is predominantly cytoplasmic. In third instar larvae, it is predominantly nuclear or cytoplasmic depending on tissues. Colocalizes with Asx on many binding sites on polytene chromosomes, but does not bind to homeotic genes loci.
Protein: PPAC_YEAST
Sequence: MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQFSGALSFLNDDYEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNISLQTISEAESAGANTLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKGLNLTSSDANTFFAWCAYEINARGYSDICNIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQKVWLSFTHDTDILNYLTTIGIIDDQNNLTAEHVPFMENTFHRSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYGYAEKRVAGTDFLKVCNVSSVSNSTELTFFWDWNTKHYNDTLLKQ
What are the official names of this protein?
Acid phosphatase PHO12.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
Protein: DCTA_RHORT
Sequence: MAFVVPAAPPRTPHKFYQILYVQVLVAIVAGVLLGHFYPDLGSALKPLGDAFIKLVKMIIAPVIFLTVVTGIAGLTDMQKVGRVAGKAMIYFLSFSTLALIIGMIVANVVHPGSGLNIDPASLDAKAVQTYTSHAHDQSLVGFLMNIIPSTPISAFASGDILQVLFFAVLFGIALATVGERGKPVLDLLNPLLQVVFRLVAIVMKAAPLGAFGAMAFTIGKYGIGSIANLAMLVGTFYLTSGLFVFVVLGLVARYNGFSLLALLRYIKEELLLVLGTSSSEAALPTLMEKLERAGCKKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNIDLSLQDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPSVPVAGMALILGVDRFMSECRALTNFIGNAVATIVVAKWEGELDRDRLALALKGGGKALLPLEHEAAIHIPSKV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QCR9_YEAST
Sequence: MSFSSLYKTFFKRNAVFVGTIFAGAFVFQTVFDTAITSWYENHNKGKLWKDVKARIAAGDGDDDDE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 9, mitochondrial, Complex III subunit 9, Complex III subunit X, Cytochrome c1 non-heme 7.3 kDa protein, Ubiquinol-cytochrome c oxidoreductase subunit 9, Ubiquinol-cytochrome c reductase 7.3 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DPHB_SULIM
Sequence: MSILSLVGLGISKKFITENAIDTLNNSDIIIFDKYTSRSCDINVDVLRRLVKGGKTLIEADRSLLENNSKIIMDYLDKNYNVSIASIGDVLIATTHVSLLIEAKQRGHNVKVIPGISVHCYLISKSLLSSYKFGKSVTVTFPYNDFIDPTPYNVIKDNKERGLHTILYLDLKSEKAMTANEALQILLRLEDKHRKNVLSKSDIVIVGARLGCDDEKIVALTVEEATLYDFGNTPHIIIIPGNLHYMEADAIKWMLMS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: BCCP_BACSU
Sequence: MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVMQQAPAAPVQAQAPQAVQPQAQQAAAPAQEAPKQDENLHKITSPMVGTFYASSSPEAGPYVTAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (By similarity).  Binds biotin (PubMed:7592499).
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.
Protein: BPTA_BORGP
Sequence: MKKIFFGLLLVCIFLVFFLFIKKENNVIYNKIVQKSGDTVLIDETYTHLFKDGNLKELVFIKSDFKLSKSEHEKNMNATGYLPDAYRAMRPGYKFDFIFHDNKILGFKSVIFEGFEDAQVSRHENSIPSEKWQKLKDYNIGDPNVNEKFFHLKFPFVVKNTLSVTISKRFFKKIKKLKRLKIILISNEDREYKIDIENFLLKYNL
What is the function of this protein?
Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the Lyme disease spirochete.
What are the official names of this protein?
Protein BptA, Borrelial persistence in ticks protein A.
What is the protein family that this protein belongs to?
Belongs to the BptA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL5_SALTO
Sequence: MTTATETKTMPRLKERYRNEIVGQLREQYQYGNPMQVPGLVKIVVNMGVGEAARDAKLIDGAVRDLATITGQKPQVRRATKSIAQFKLREGMPIGAKVTLRGDRMWEFLDRLLSIALPRIRDFRGLDGRKLDGNGNYTFGLTEQSVFHEIDQDKIDRQRGMDITVVTTATTDDEGRALLKFLGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: METK1_CAEEL
Sequence: MSSKFLFTSESVSEGHPDKMCDQISDAVLDAHLKQDPNAKVACETVTKTGMVMLCGEITSKAVVDYQVLVRRVIEKIGFTDSSIGFDHKTCNVLVALEQQSPEIAAGVHVNKDGEDVGAGDQGIMFGYATDETEETMPLTLILSHKINAELHKLRRNGTLPWVRPDSKSQVTIEYESRHGATIPLRVHTVVVSTQHSPDVTLEKLRETILADVIKKVIPASLLDESTVFHINPCGTFIVGGPMGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVATSLVKAGLAKRVLVQLSYAIGIAKPISVLVYAFGTSPLTDEELHQIVEDSFDLTPGKIIKELDLKRPIYEKTAENGHFGHSEFPWEQPKALKISPALLEKAKGNPIPATSAIAH
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (SAM) from methionine and ATP (By similarity).  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (By similarity).  May be required for the majority of global SAM production under normal growth conditions (PubMed:22035958).
What are the official names of this protein?
Probable S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: DADA_YERPY
Sequence: MRVVILGSGVVGVTSAWYLAKEGHDVTVIDRQDGPAQETSAGNAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAIRLDGSSLQLRWMWQMLRNCDTSHYMVNKSRMVRLAEYSRDCLKDLRAATGIQYEGRQGGTLQLFRTEQQFDNAAKDIAVLDDAGVPYSLLTAEQLATVEPALAKVAHKLTGGLRLPNDETGDCKLFTERLAKMAEQAGVKFIFNRSVDKLLVEGDQIAGVLCGDDIIKADAYVVAFGAYSTALLAGLVSIPVYPLKGYSLTIPITDPASAPFSTVLDETYKIAITRFDDRIRVGGMAEIVGFNTQLAPARRETLEMVVRDLYPHGGDISQAVFWSGLRPMTPDGTPIVGRTPLKNLYLNTGHGTLGWTMACGSGQLLADIIQGRRPAIVADDLSVARYRTGFQPLNIAPLHDIHPIR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: YIDD_PROMT
Sequence: MLTKINKAIALVFVSLISFYQKWISPLFGPSCRFIPSCSAYGIEAVNKHGPWRGGWLTLKRLSKCHPLTPCGCDPVPEK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DTD_CHLT3
Sequence: MRVLVQRVAHASVVVAGETIGKISRGLLLLVGVTHTDSQNDLEWMAKKILKLRIFEDDEGKMNRSVEDVGGAILAVSQFTLYGDARKGNRPSFLEAARPEQAQASYQDFVKMLKLLGSVPVETGQFAAHMEVSLLNDGPVTLMLESPTKEEK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_SYNJB
Sequence: MDSQSVAPVVLVILDGWGYRDALDGNAVLAAETPVLDSLWAAYPHTLLQASGRAVGLPAGQMGNSEVGHLTLGAGRVVPQELVRISDAIETGSLFQDPLLMQVCRQLRERGGRFHFVGLCSEGGVHSHIDHLYGLLKLAAQAEIPAYVHAITDGRDTLPRDGARVLAALEKELQWLGNGVIATLSGRYYAMDRDRRWERTQKAYEIMTQDGPGRGQSAAEVMEAFYAQDLTDEFIPPTRLAPGAVQPGDAVLFFNFRPDRARQLTQAFVCPDFSGFQRPLLPALTFITMTQYEADLPVQVLFKPQNLNHLLGQVVSEAGLKQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVTTYDQAPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVGHTGNYEATIRALETVDRCLGRLLAAVVDAGGTTLILADHGNAELMWDENGNPWTAHTTNPVPCILVEGERRKIPGCGGDVKLRSNGTLADVAPTLLEILGLPQPPEMTGRSLLQPAEYTILQRQPSPVGR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CLPC_STAAM
Sequence: MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
What is the function of this protein?
Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat-denatured proteins for degradation by ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpC.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: 53DR_STAAS
Sequence: MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
What is the function of this protein?
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.
What are the official names of this protein?
Putative 5'(3')-deoxyribonucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: G6PI_ASPOR
Sequence: MPAFSQATDLSAWKELQEHHTAVGRNIVLKEAFEKDPQRFEKFSRTFKNTVDNSDILFDFSKNFLTEETLSLLVKLAKEANVEELRDAMFKGEHINFTEDRAVYHAALRNVSNEPMQVDGKSVVEDVNSVLEHMKEFSEQVRSGEWKGYTDKKIDTIINIGIGGSDLGPVMVTEALKPYGAPGMKLHFVSNIDGTHIAEALKDSNPETTLFLIASKTFTTAETTTNANSAKKWFLETAKDESHIAKHFVALSTNEAEVTKFGIDKKNMFGFESWVGGRYSVWSAIGLSVALYIGYDNFHQFLAGAQAMDKHFREAPLEQNIPAIGGLLSVWYSDFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKAITRSGEYVKYTTGPILFGEPATNAQHSFFQLLHQGTKLIPSDFIMAAESHNPVEGGKHQRMLASNFLAQSEALMVGKTPEQVKTEGAPDNLVPHKTFLGNRPTTSILAQKITPSTLGALIAYYEHLTFTEGAVWNINSFDQWGVELGKVLAKKIQQELETSGAGAGHDASTSGLLAAFKQKANLA
What is the function of this protein?
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: 3L2N3_BUNCA
Sequence: IVCHTTATSPISAVTCPPGENLCYRKMCDAICSSRGKVVELGCAATCPSKKPYEEVTCCSNDKCNPHPKQRPG
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (By similarity).  Mice injected with this toxin develop flaccid paralysis followed by death.  Irreversibly inhibits twitches in a concentration-dependent manner in rat phrenic nerve-hemidiaphragm and chick biventer cervicis muscle (PubMed:19728988).
What are the official names of this protein?
Alpha-bungarotoxin N3, AlphaN3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIE_SODGM
Sequence: MTTQAIHSVLAMMNITAEQAAGNTLTLSAPATAGAGFMSELNSSIKQINGMQIEARRKAEKFELGVPGIALNDVMVDMQKASLALHLGIQVNNKLINAYQEVMNMAV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: PSMG3_DICDI
Sequence: MNSLLIDSSNPSYDAMNNDNLKNSIEKNHPVKSKVLSKKINNVDTDIAISSFADAIFITISQNQKFNTWIRASKSDGILLDEPSYQIDTLLGNNQDVLFSIYARQLIENIGETSNKSLMLSISITDKSKDTFKQILSTIFENKVW
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome.  May cooperate with psmg1-psmg2 heterodimers to orchestrate the correct assembly of proteasomes (By similarity).
What are the official names of this protein?
Proteasome assembly chaperone 3.
What is the protein family that this protein belongs to?
Belongs to the PSMG3 family.
Protein: FC2_PHOAM
Sequence: MGSTAEDFVIKPMKGEHGFGAEIYGLDVNNITDEQVDRLRDTIQRYLLVVLKHQHDETPQKNWELLNRLSPDAPKFTPEEWALMYNPDPQGAGILPKLGYLVLPGTERLFLMGKGYQGEDHWGLKDIDIPEVFADAYYSKPLPHEDYHNGVARFQSWHIDGPSYKIDHPMFTSFRIIKFPEGEQTVDWADGSGLTKKVKAGRTAFFSSAKLYDMLTKEEQAIADYSWAEYMYFPYEWILRCRGNPQGLLVACEGREVPDEQMDAMPRNPEDQLVLPLVWVNPVTGGKHFHVQPNIVRRVFVRSGPDEEPKIIDDVKEVRDFFTKFQYRIIRPENIYVGPEEEGDQLLFFNWGVMHSKIDYPIEMGTRTTHQGWLAGDRPPKGPVPIPDPRARSSIYYQK
What is the function of this protein?
Alpha-ketoglutarate-dependent dioxygenase; part of the 2 gene clusters that mediate the biosynthesis of fusicoccins, diterpene glucosides that display phytohormone-like activity and function as potent activators of plasma membrane H(+)-ATPases in plants by modifying 14-3-3 proteins and cause the plant disease constriction canker (PubMed:21299202, PubMed:22870285).  The first step in the pathway is performed by the fusicoccadiene synthase PaFS that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) and successively converting GGDP into fusicocca-2,10(14)-diene, a precursor for fusicoccin H (PubMed:17360612).  The second step is the oxidation at the C-8 position by the cytochrome P450 monooxygenase PaP450-2 to yield fusicocca-2,10(14)-diene-8-beta-ol (PubMed:22870285).  The cytochrome P450 monooxygenase PaP450-1 then catalyzes the hydroxylation at the C-16 position to produce fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:22870285).  The dioxygenase fc-dox then catalyzes the 16-oxydation of fusicocca-2,10(14)-diene-8-beta,16-diol to yield an aldehyde (8-beta-hydroxyfusicocca-1,10(14)-dien-16-al) (PubMed:21299202, PubMed:22870285).  The short-chain dehydrogenase/reductase fc-sdr catalyzes the reduction of the aldehyde to yield fusicocca-1,10(14)-diene-8-beta,16-diol (PubMed:21299202, PubMed:22870285).  The next step is the hydroxylation at C-9 performed by the cytochrome P450 monooxygenase PaP450-3 that leads to fusicoccin H aglycon which is glycosylated to fusicoccin H by the O-glycosyltransferase PaGT (PubMed:22870285).  Hydroxylation at C-12 by the cytochrome P450 monooxygenase PaP450-4 leads then to the production of fusicoccin Q and is followed by methylation by the O-methyltransferase PaMT to yield fusicoccin P (PubMed:22870285).  Fusicoccin P is further converted to fusicoccin J via prenylation by the O-glucose prenyltransferase PaPT (PubMed:22287087).  Cytochrome P450 monooxygenase PaP450-5 then performs hydroxylation at C-19 to yield dideacetyl-fusicoccin A which is acetylated to 3'-O-deacetyl-fusicoccin A by the O-acetyltransferase PaAT-2 (PubMed:22870285).  Finally, a another acetylation by the O-acetyltransferase PaAT-1 yields fusicoccin A (PubMed:22870285).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase fc-dox, Fusicoccin A biosynthetic gene clusters protein 2.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.