PharMolix/UniProtQA huggingface dataset:
Protein: TELL_STAAC
Sequence: MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS
What are the official names of this protein?
TelA-like protein SACOL1441.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: NUDI_ECOLC
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWAISGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: RS11_STREM
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RT10_CRYNJ
Sequence: MALPAARSALSARAFIRPAAALNAAASSSRYLSTTTPRHDAPVATTPGNSETALPVPLPGIKFLSMPPVTPHPPTHGIHVATLHLQAHHPYNLDLVSQFAVHSAHSLNIPTSLPAFLPREKSLYTVLKSPFVKKKAQENFERRTHKRAIKVYDADREAIDLWLRYLRQNALPGVGMKAYIHEWVELGFGRKEAEGQNEIEMEVEEKRIQDAAAELVKALSEGEGEDQAEGVQKIVDAAREEKPAEKLKEEEAKSS
What is the function of this protein?
Involved in mitochondrial genome encoded proteins translation.  Involved in the binding of tRNA to the ribosomes (By similarity).
What are the official names of this protein?
37S ribosomal protein S10, mitochondrial, Mitochondrial ribosomal small subunit protein 10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL3_THERP
Sequence: MIEGLLGRKLGMTQIFDDEGRAIPVTVLEVGPCVVTQVKTSDRDGYQAVQLGFGHRKRQNRPMQGHLRASGASPRYLKEVRVDDATRFQVGQVIDCTIFQPGQLVDVIGWRKGRGFQGGVKRHGFAGGPKTHGQSDRHRAPGSIGPTTDPGRVHKGKRMAGRMGPVRVTVQNLRVERVDPQRNLVLVRGAVPGHPNGLVIVRYAVKQRRAKATA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GMPPB_XENTR
Sequence: MKALILVGGYGTRLRPLTLSVPKPLVDFCNKPILLHQVEALVKAGVNHVILAVSYMSDMLEKEMKEQEKRLGIRISMSHEKEPLGTAGPLALARELLTENSDPFFVLNSDVICDFPFEEMVRFHKHHGKEGTIVVTKVEEPSKYGVVVYEAESGQIQRFVEKPQVFVSNKINSGLYIFSPAVLDRIQLRPTSIEKEIFPAMAQEGQLFAMELQGFWMDIGQPKDFLTGMCMYLQSVRQKHPEWLHVGPGFIGNVLVDPTAKIGQNCSIGPNVTIGPGVTVEDGVRIKRCTIMKGSRLHSHSWLESSIVGWSSSVGQWVRMENVTVLGEDVIVNDELYLNGANVLPHKCISESVPEPRIIM
What is the function of this protein?
Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids.
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase beta, GDP-mannose pyrophosphorylase B, GTP-mannose-1-phosphate guanylyltransferase beta.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: MYRIP_DANRE
Sequence: MGRKLDLSGLSNNEAEHVLRVVQRDMQLRKKEEERLSEMKQELEEEGSRCLLLSKQQKFNEHCCIRCCSPFTFLLNPKRQCLDCHYNICKSCCSYSQSERGYICAACQKSRHLRTQSLEWFYNNVKSRFKRFGSAKVLKTLYRKHIIERGALSELPEVSAHEGSNDNGSICDGSDSTLYKQSEGHSMADTLTVALRVAEEAIEEAIAKAENYKDSLEKQNEARYLHEHKEELIEELATTIVQKIIQRGKRPEIQEEYEFVWPQNQKSELPSPTSTQNPLATQNSHSTSQPGAVAQSDISKRSRSAYSSDDSPEKGPEVGMAPGVPKSTEVETDIQNYSSLRRESRALSLPGWKSVDRLENSSASSVLQSPDGNWIALQSSQHSRPSLLTKRKSLVFSVLEKESGVVSAYDEMGSDSDPEDQGGWGAALLQFRRRLSDETYYTDSQHDPEWTFTQHPPITSPSSGQYTNTETLNSDSETSPSPSTRARRAPVMKKGPPETHLYPYYRHPADIVALPQLKPDVLDVNFNPHLGGDSSDGEERSEQVKRSRRRRKSKRETSEHSRAHNALYSAATAENSTVLLNAMMMRRQQSQENTVPLNHQTPDSVTSPDILTFNNMSPEPEYQNTLAHNSSAASLPLLSQLGSNNPGFAPQDPLLRAFPVNETLEEELKYKLSELIGQVSERDVKSSDFEPISEVGNKQEDRVSEKDSGKLRPKERRESKRESKLREMEKQSERQTVKLMDTSDAVRQINIERQMKKERERQRDIERQVERERERQRELEKQIEKDRERRREIEMQVEKKQERQKEMEKQLKQEQERQSEIERDLEKKRKSIRMEKRN
What is the function of this protein?
May link secretory vesicles to actin filaments (By similarity).  May function as a protein kinase A-anchoring protein (AKAP).  May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis (By similarity).
What are the official names of this protein?
Rab effector MyRIP, Exophilin-8, Myosin VIIa- and Rab-interacting protein, Synaptotagmin-like protein lacking C2 domains C, SlaC2-c, Slp homolog lacking C2 domains c.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle.
Protein: RL1_LEPIN
Sequence: MQRGKKYRAHKEKVDSTKFFSIDKAVELAKSTSYTKFDGTLEIATKVNYKSLQNIRGTISLPHGTGKKIRVLVFCKGDKQNDAKAAGADFVGDTDLIEKVAGGWTDFDACVATPDMMKDVGKLGPILGRKGLMPKPKAGTVTTDVAKAVNELKAGRIEYRPDKGGVVHLGVGKVSFDNTKLIENIRTVVQTLMRDKPSDAKGEYLKTFSISPTMGVGVKVDVKELVNTSI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HIP28_ARATH
Sequence: MNLTLNLIQLQTIEMRVHMDCVGCESRVKNALQKMRGVDAVEIDMVQQKVTVTGYADQKKVLKKVRKTGRRAELWQLPYNPDHMGGSSSNGGYFYNPQGCNGPINHAAPVPTSSYNYYKHGYDSNDYSSYRHHPVHASIFSHQTGSKFSDENPNACSIM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 28, AtHIP28.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RNPA_CLAM3
Sequence: MLARRNRVTSGADYRIIVRRGRRTTTGTAVVSALAGPDDAPTRFGFIISKKVGNAVTRNLVRRRLKAVSAGLLHSVPPGTSIVIRVLPGMERTAWDTLQEEMASAVTRAVRTI
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: AVLB1_WHEAT
Sequence: MKVFILALLALTATTAIAQLETTCSQGFGQYQQQQQPGQRQLLEQMKPCVAFLQQQCRPLRMPFLQTQVEQLSSCQIVQHQCCQQLAQIPERIRCHAIHSVVEAIMQQQSQQQWQERQQQAQHKSMRMLLENLSLMCNIYVPVQCQQQQQMGQQQQQQQLQEQLTPCATFLQHQCSPVTVPFPQIPVDQPTSCQNVQHQCCRQLSQIPEQFRCQAIHNVAEAIRQQQPQQQWQGMYQPQQPAQHESIRMSLQALRSMCNIYIPVQCPAPTAYNIPMVATCTSGAC
What is the function of this protein?
Seed storage protein.  Might be integrated via inter-chain disulfide bonds within the glutenin polymer.
What are the official names of this protein?
Avenin-like b1, TaAvlike-b1.
What is the protein family that this protein belongs to?
Belongs to the prolamin family.
Protein: LEPA_MESFL
Sequence: MDKSKIRNFSIIAHIDHGKSTLADRILELTNTVTKREMQEQLLDSMDIERERGITIKLNSVQLYYKAKDGQEYTFHLIDTPGHVDFAYEVSRSLAACEGAILVVDATQGIEAQTLANVYLAIENNLEIIPVINKVDLPSADAERVKEEIENTIGIDCSDAPLISAKTGLNVEDVLEAIVNKIPAPYDADDAKPLRALIFDSYYDKYLGVVMSIRVREGSIKVGDRIKLMANGSSYEVTELGVKNPKIVKKDQLSAGEVGWVAASIKTIKDINVGDTITTVTNSALHPLDGYKKLKPMVYCGIYPIDTNQYQDFKEALEKMELSDSSLVYEPETSQALGFGFRVGFLGLLHMEVVQERLEREYNLNLIATAPSVIYKIHLTDGTMIEIDNPAKLPDPQKIKFMEEPFVNVKIMTPKESVGDLMSLCQNKLGTYKDLQVVDDNRMMLVYDMPLAEIIFDFFNKLKSISKGYASFEYEMIGYQESQLVKMDILLNGDMVDAFSMIVNKHFAYQRGAALTKKLKELIPRQNFEVPVQATIGNKVLARETIKAYRKDVTWKLHAADKSRRKKLLNKQKEGKKKMKEIGSVEVPQEAFIAVLKLDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FOLD_WOLTR
Sequence: MTIIIDGKKIASGLCEKLSQRIDVLKREHSIFPCLKVIFVGNNPASQVYVRNKQKKAESIGISSETIVLPDNILENELIEKINELNNDRFVNGILVQLPLPNHINASKVINTVSVEKDVDAFHRENVGKLVKGEKNCLVPCTPKGALHLIKLVETNLSGKNAVVIGRSNIVGKPMFHLLLQENCTVTILHSQSKDLAEYCSKADVVVTAVGKPNFVQEGWIKEGAIVIDVGINSVSIEGKTKLIGDVDFDRVKEKTKAITPVPGGVGPMTIAFLMINTVIAACLQKKVDASDFVS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CEP3_HHV8P
Sequence: MGFLLSICKRPSQPVDVDGEPLDVVVDYDPIRVSEKGMLLEQSQSPYPALKKKKKNKEAIY
What is the function of this protein?
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes.  Participates also in viral entry at the fusion step probably by regulating the core fusion machinery.
What are the official names of this protein?
Cytoplasmic envelopment protein 3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 3 family.
What are the subcellular locations of this protein?
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: GSA_SYNS3
Sequence: MAPVPVTASNLNTSHSEAIFSAAKALMPGGVSSPVRAFKSVGGQPIVFDRVKGPYAWDVDGNKYVDYIGSWGPAICGHAHPEVISALQEAIEKGTSFGAPCALENTLAEMVIEAVPSVEMVRFVNSGTEACMSMLRLIRAFTGRDKIIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPRSTTANTLTAPYNDLESVKQLFAENPDAIAGVILEPIVGNAGFIQPEPGFLEGLRELTKENGALLVFDEVMTGFRISYGGAQAHFGVTPDLTTMGKVIGGGLPVGAYGGRKEIMEMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLKQPGSYEKLTATTERLIQGILDAGREAGLPITGGSVGAMFGFFLCEGPVRNFEEAKATDSVRFGLLHRAMLERGVYLAPSAFEAGFTSLAHSDENIDATIQAFRDSFAAIS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_CERS1
Sequence: MTTTIYILNGPNLNLLGQRQPEIYGHETLADVERRCAEVAAEKGFSVRLFQSNHEGTIIDQIHEARQAACGIVINPAAYTHTSVAILDALHAFEGPVIECHISNVHKRESFRHHSYVSLRADGVLAGFGIEGYELAVRRICSLCAGG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: KPYK1_CANGA
Sequence: MDSRLARLTTLQTSAGEELRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNEVDYPIPPNHEMIFTTDDKYAKACDDKIMYLDYKNITKVISAGRIIYVDDGVLSFEVLQVVDDKTLKVKSLNAGKICSHKGVNLPGTDVDLPALSEKDKADLRFGVENGVHMIFASFIRTAQDVLTIREVLGEDGKDIKIVVKIENQQGVNNFDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAVTTMAETALIAEQAIAYLPNYDDIRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTARLVSKYRPNCPIILVTRNARTARFSHLYRGVFPFVYEKESVSDWTEDVEARLNFGIEQAIEFGILKKGDTYVSIQGFKAGVGHSNTLQVSTA
What are the official names of this protein?
Pyruvate kinase 1, PK 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: DYT1_ARATH
Sequence: MGGGSRFQEPVRMSRRKQVTKEKEEDENFKSPNLEAERRRREKLHCRLMALRSHVPIVTNMTKASIVEDAITYIGELQNNVKNLLETFHEMEEAPPEIDEEQTDPMIKPEVETSDLNEEMKKLGIEENVQLCKIGERKFWLKIITEKRDGIFTKFMEVMRFLGFEIIDISLTTSNGAILISASVQTQELCDVEQTKDFLLEVMRSNP
What is the function of this protein?
Transcription factor.  Involved in the control of tapetum development.  Required for male fertility and pollen differentiation, especially during callose deposition.
What are the official names of this protein?
Transcription factor DYT1, Basic helix-loop-helix protein 22, AtbHLH22, bHLH 22, Protein DYSFUNCTIONAL TAPETUM 1, Transcription factor EN 49, bHLH transcription factor bHLH022.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADK1_ARATH
Sequence: MSSTYKLNHTDSFANGDAKSLLPNPENGFTHLTSLAQSEKAVQELLLQQTPMQATDDHLVEFSEALRTVAKALRGAAEGKALAQAEAAEWKRRYELERSKNVELQHKELSNGVCADESNGQRMEHLAKSPRLYAQEISSNGMETICSHEVLQDGGFNSFNNKLKRKASFKLSWGCKGMANDQHKKEIVSFERGNISTAERSSKQISLTWESDPQTVLIITKPNSTSVRVLSVDMVRWLRTQKGLNIYVEPRVKEELLSESSSFNFVQTWEDDKEISLLHTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKATHEYEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTACQVESTNDFLRSIHDGLHWNLRKTQSADGP
What is the function of this protein?
Phosphorylates both NAD(+) and NADH, with a twofold preference for NADH.  Source of the cellular reductant NADPH which is an important antioxidant factor.
What are the official names of this protein?
NAD(H) kinase 1, AtNADK-1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
Protein: DUT_PARPJ
Sequence: MKLDLKILDARMRDQLPAYATTGSAGLDLRACLDEALTLKPGETALVPTGLAIHVGDAGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISTWNRGETTFVLNPMERLAQLVIVPVVQAEFNIVDDFETSDRGAGGFGSTGKH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YIDC_RUTMC
Sequence: MNNQKNFLIVAIFLSVFLLWDKWGVTHVVGANGNLISQTKIKDASTINNSLTNKNLNASSIIHRNAELDLPNTITKNQAPFTTVVTDLLTLEISHKGGTIQNAWLNDYPIEINSEQKFQLLSNKADEIFQAQSGLLPQGQTPTHHSIFSSKNSHYQMDGNSLVVPFTWKSENGIKVIKRYHFNKNSYVIGIDYQITNTTNNTLNITSYTQLVRNALDQSNMIIPTYTGGARFDDQDVYEKIEFEDFNDQPKTTSKGGWIAMIEHYFFVAAIPDVNQIHTYSSKIINGEYLLTVVNPELVIAPGAIVTLPSSSLYIGPKEQKQINNVAPGLDKTVDYGVLFIIAKPLSELLNWIYSIIHSWGYSIITLTLLIKLAFYKLSEKSYRSMAGMRQLAPRLTKLKETYGDDKQKLGQKTMELYKKEKINPASGCLPILVQIPVFISLYWVLLEMVELRQAPFWYLTDLSAQDPYYILPLIMGVSMFAQQKLNPPPPDPMQAKIMMALPFVFTIFFLWFPSGLVLYWVVNNILSITQQWVINKRING
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH602_PROMA
Sequence: MAKRIIYNEQARRALERGIDILAESVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKAGLRNVAAGANAITLKKGIDKATDFLVKKIQEQAKPISDSNAIAQCGTIAAGNDEEVGQMIADAMDKVGKEGVISLEEGKSMETELEVTEGMRFDKGYISPYFATDTERMEAVLDEPYILLTDKKIGLVQDLVPVLEQIAKTGKPLLIVAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMLEDMAVLTNGQLITEDAGLKLENATLDMLGTSRRVTINKDTTTIVAEGNEAAVQARCEQIKKQMDETDSTYDKEKLQERLAKLAGGVAVVKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLAHLASEVHSWAASSLSGEELIGANIVEAALTAPLMRIAENAGANGAVIAEHVKSKPLNDGYNAASGEYVDMLSAGIVDPAKVTRSGLQNASSIAGMVLTTECIVADLPEKKDVASGGAGGGMGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_DESRM
Sequence: MAKEIIFREDARRALERGVNALAEAVKVTLGPKGRNVVIEKKFGAPTITNDGVTIAREIELEDNFENMGAQLVKEVATKTNDVAGDGTTTATVLAQALVREGLKNVAAGANPMIIKRGIEKAVEKAVEEIKAMAKPIESKEAIAQVATVSANDDSIGNLIAEAMEKVGKDGVITVEESQGIGTNLEVVEGMNFDRGYISPYMITDTDKMEAALTDPYILITDKKVSSVQELLPVLEKVVQTGNKPVLLICEDLEGEALATLVLNKLRGTLNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEEVGLKLDKAELDMLGTARQIRVKKEETIIVGGAGEQAQIEGRIAQIKKQIEETTSDFDREKLQERLAKLAGGVAVIQVGAATEVEMKEKKLRIDDALNATRAAVEEGIVPGGGSAFVNIITTLDSVQLEGDAKTGVDIVKRALEEPLRQIANNAGLEGSVVVEKVRTTGKGFNAMSEEYVDMIAAGIIDPAKVTRSALQNAASIAAMVLTTETLVADKPEKDAPNPMAGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_THEMA
Sequence: MWSDPIADMLTRIRNANMVFKEYTDIPASNLKKKICEILKREGFIADYKYIEDGKQGILRVYLKYKGGRKNRERVIHGIVRVSHAGRRIYVDKDHIPKVKNGLGIAILTTSKGVLTDKEARQLGVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: IL13_CAMBA
Sequence: MALWLTVVIAFTCIGGLASPVPTPSPKALKELIEELVNITQNQKAPLCNGSMVWSINLTTSMYCAARESLINITNCSVIQRTQRMLNALCPHKLSAKVSSEHVRDTKIEVTQFIKTLLQHSRNVFHYRSFNWSKKS
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection.  Synergizes with IL2 in regulating interferon-gamma synthesis.  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6.  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
What are the official names of this protein?
Interleukin-13, IL-13.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MCD4_NEUCR
Sequence: MAAFPRFRFLAIAVIFHFAYIFSIFDIYFVSPIETGMRLFNVQRPPNRSAPADRLVLFVGDGLRADKALQSHPEPYPKSDADLTPRPLAPYLRSKILEQGTFGVSHTRVPTESRPGHVALIAGLYEDVSAVTTGWKLNPVNFDSLFNRSRHTWSWGSPDILPMFEQGAVPGRVDAYTYGHEFEDFSSDATQLDLWVFDHVKDFFAEARRNKTLAEALRQDKIVFFLHLLGLDTTGHSYRPYSKEYLNNIKIVDQGVKEVAELFRDFYRDGRTAFVFTADHGMSDWGSHGDGHPDNTRTPLIVWGSGVAKPQLYPGEVAPGHDEYSADWNLDHVRRHDVAQADVAALMSYLVGVEFPANSVGELPLSYLAADIKEKAEASLVNVQGILEQYRVKEEKKKATELKYRPYQPFGENGLSPERRVAEIRQLIDAGRYEEAIEESAALMKVGLGGLRYLQTYDWLFLRALITIGYLGWIAYALTTVVDLHVLHGRVRPSRTLGGGLFFTSVLVALYASLVISKSPLTYYVYAFFPVFFWEEVYAHRESLAAGRKELLGHINSGGSVASFVLNSALYVGVIESLALGYIHREILSVLFVLGSFWPFTHGLSFLKKHGALSATWFLACIAMSTFTLLPAMKAENVNLITIGGVLMVVIGLLYLIFEDFVLADFSWNAKPTSRNHLSRSLVGIQVGLTVLSIIITRSSALSLQAKQGLPRGNQIMGWVTLVASLLMPLAYRLRPNNHYMHRILVIFLTCAPTFVILTISYEGLFYLVFSALLVSWVRLEHAVQKFTSSKAPQTAATKKPTTTTESHLPAPFRPLTLHDARVALFFFILLQSAFFSTGNVASVSSFSLDSVYRLIPIFDPFSQGAMLILKLMIPFALISANLGILNKRLGVAPSALFMVVMGISDILTLYFFWVVKDEGSWLEIGSTISHFVIASLLCVFVSALEPVSAAFIAGVEVGEESELKEEGKVAEKVVEKVNEAVEGLVSGGDGGGDES
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity).
What are the official names of this protein?
GPI ethanolamine phosphate transferase 1.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.