PharMolix/UniProtQA huggingface dataset:
Protein: AAP1_ARATH
Sequence: MKSFNTEGHNHSTAESGDAYTVSDPTKNVDEDGREKRTGTWLTASAHIITAVIGSGVLSLAWAIAQLGWIAGTSILLIFSFITYFTSTMLADCYRAPDPVTGKRNYTYMDVVRSYLGGRKVQLCGVAQYGNLIGVTVGYTITASISLVAVGKSNCFHDKGHTADCTISNYPYMAVFGIIQVILSQIPNFHKLSFLSIMAAVMSFTYATIGIGLAIATVAGGKVGKTSMTGTAVGVDVTAAQKIWRSFQAVGDIAFAYAYATVLIEIQDTLRSSPAENKAMKRASLVGVSTTTFFYILCGCIGYAAFGNNAPGDFLTDFGFFEPFWLIDFANACIAVHLIGAYQVFAQPIFQFVEKKCNRNYPDNKFITSEYSVNVPFLGKFNISLFRLVWRTAYVVITTVVAMIFPFFNAILGLIGAASFWPLTVYFPVEMHIAQTKIKKYSARWIALKTMCYVCLIVSLLAAAGSIAGLISSVKTYKPFRTMHE
What is the function of this protein?
Amino acid-proton symporter.  Stereospecific transporter with a broad specificity for histidine, glutamate and neutral amino acids.  Reduced affinities for asparagine and valine.  Involved in amino acid uptake from the apoplastic cavity into the embryo cells for storage protein accumulation and in root amino acid uptake.
What are the official names of this protein?
Amino acid permease 1, Amino acid transporter AAP1, Neutral amino acid transporter II.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS4_XANCB
Sequence: MARYIGPTCKLARREGADLSLKSPARALDSKCKLEQKPGQHGAARKGKLSDYATQLREKQKVKRIYGLLERQFRNYYKKASTKKGNTGENLLQLLETRLDNVCYRMGFAVTRPAARQLVSHRGVLVNGKSVNLASYQIKAGDAITLSEKAQKQLRVQEALTVAEQHDMTPSWVEVDSKKFSGVFKAVPDRADLPSDINEALIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MCRZ_METTH
Sequence: MTYKAQYTPGETQIAENRRKHMDPDYEFRKLREVSDEDLVKVLGHRNPGESYKSVHPPLDEMDFEEDIVRDMVEPIQGAKEGVRVRYIQFADSMYNAPAQPYDRARTYMWRYRGVDTGTLSGRQVIEMRELDLEGVSKELVETELFDPATTGIRGATVHGHSLRLDENGLMFDALQRYVFDEEKGHVVYVKDQVGRPLDEPVDMGQPLGEDELKKITTIYRKDNIAMRDDKEAIEVVENIHTGRTMGGFGMDVFKDDLRKRLGDD
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit gamma, MCR II gamma, Coenzyme-B sulfoethylthiotransferase gamma.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase gamma subunit family.
Protein: BLAA_STRCI
Sequence: MDVVNACRAFVKVSERGSFTVGAAAAQMSQSVASRRVAALEKHFGERLFDRASRRPSLTPFGRDMLPAARRLVRVADVLEDEARAARSRPMRLAVPASCTTAELARLVADSRERDIRLDVRTAGPEQRAELVRTQEVRAGLLAVPPDQALWAVPLGLAGADEPQTRRVFVESLRLRRGEPGPARCIRVQPEDDVPHIQGRLARLRDAVGLRPAQLSVAPDLTSATADVLSSDDLLLCSPAQAAELGLYWRPVGELRLARGYVLDAAVEADAERLRGRLAPYLARALGATADHGPDPATGAGPGADAGTEPGARAEPGAPEEGAQAC
What is the function of this protein?
Positive regulator of the expression of the gene (blaB) for beta-lactamase.  It binds to the blaL-blaA intercistronic region.
What are the official names of this protein?
HTH-type transcriptional regulator BlaA, Beta-lactamase regulatory protein BlaA.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: LEU1_THESQ
Sequence: MRRIKIFDTTLRDGEQSPGASMSIEEKVEMALMLEDLGVDLIEAGFPVSSPVQFEAVKRVASAVQKPIVVGLARCVEKDIDAAYEALKDRPKDKRMIHVFIATSPIHRKYKLRMEKEEILERIRRYVGYAKQFFDLVEFSAEDASRTEVPFLIEAYKTAIEAGATTINVPDTVGYALPDEFGELIKTLREGVPGIENVDLSVHCHNDLGLAVANSLAAVQNGATQVEVTLNGIGERAGNCALEEFVMILKVRKDKLPYETGIKTELIYPASRLLTHITGLIPSRNKPIVGENVFLHESGIHQDGVLKHRETYEIMKPSDIGRSSETLVLGRHSGKHALRKKLETYGIKLDEETFQKVFEKFTELADRKKEVYDDDLFSIVSEVLREPINGYKLVHFHVHTGNTLLPTAAVVLQVGNEKREAAEAGNGPVDAIFKAIDKALGIQPKLEEYIIQAVGTGKNAQGEVKLTLRIDNELYSGRGVSTDIVEASAIAYINAINKYLIAKGLLRKNGGAE
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: YCIB_CUPMC
Sequence: MKFLFDLFPVILFFVAFKLFGIYPATAVAIGATVVQIAWVHFRHGKAEPMQWVSLAIIAVFGGATILLHNETFIKWKPTVLYWLFAVTLIGSVIGWRKNLIRAMMEKQVTLPEPMWGRLNVAWAGFFAVMGVLNLYVAYQFSTDTWVNFKLFGSMGLMLVFIVAQSIWLSRHIQETPSE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PREU4_PREIS
Sequence: MEAVVSSAPFIAPIDSFEHCQIFLFGDLASPFEDDLAQLLHCKNNALLQSFFDQVNRAYRTEFATLPAEQQEWLPRFTDLVDLVSNLNSTIGARALRFGLLCVYQLGRLIHSDVLPHVDTSYLIGVCTGSFAAAAVSASRTMAELVPAGVEAALAAFRTGLHSFKAQQDIVPTTVEQLQSWSFVTSMTESQALETIREFTDKMHLTQSQRPYLSAVSPSSVTISGPPRTLKHLIESCAIKAHPIQVQSPYHAAHLNGPDEVDDVLGHLRDERLSEYRQHIPIWSIATGRDVPAHDFHGLLRRAIDETLCEQVRWDKLCPALKSHLAQRSSLKSCILFPVTSNAATLLSSALQHESRLDVTISNALNTRVERVNTSAAPGKFSDSKIAIVGFSGRYPEAASNDELWEVLKSARDCHRTIPEDRFDWAAHYDAAGKKKNHTRVKFGCFINDPGVFDARFFNLSPREAENTDPAQRLALMSAYEAIEMAGLVPDRTPSTQRDRIGVFFGVTSDDWREVNSGQDIDTYFIPGGNRAFVPGRISYFFRFSGPSISVDTACSSSFAAISTACSYLWQGDCDSAIAGGTNVLTNPDNFVGLDRGHFLSQTGNCNPFDDSASGYCRADAVGAVVLKRLEDALADHDPIFGVIAGCSTNHCGQTVSITRPHEGDQLALFKRILRHSNTDPRDVGYVEMHGTGTQAGDAAEMRSVLAAFANDHLRPRPLHLGAIKANVGHSESASGVTALIKVLMMMQHSEIPPHRLNGKLNRNYPSDLADRNVHIPFKTTPWRREDAGGKRMAFLNNFSAAGGNTAVLLEDAPVLEDGENVVSDPRTVLPLTVSAKTGKALTENIHALVNYLNDNPDTSLSALSYTTTARRIHHKFRVLVSGSDVAAVKAALQRREHDVHKIKTVPPTVAFVFTGQGTLYAAIGKEFFEHVAIFRTDLVRFDRIAQRHGFPSFLGLIDGGEEHVDPLKVDPVVAHLAVTCVQMALAHIWRLWVGEPSCVTGHSLGEYAALYTAGVLSASDTIYLVGSRARLLTKHCNKLTHGMLAVKAPAAVVAAELASSGSDCTIACINSPVSTTVSGPKKAVQDLSTWLKTRNIDAIPLEIPYAFHSAHVDPILHEFENLASSVHFHEPAVPYLSPLLSWTVTEPGILTASYLARSSRQCVNFLGAIEHARETKLVNDTTIWLELGTHPACSGMLRQIIGPQASTVPVLRKDGHIWKVVVAALDTLYHNGVEIQWNEFHRGLDAAQRVLALPSYKWTLQRYWIQYRHNFCLTKGDDPATLVQQTIPPPPLPARTPSLSSSVHRVLESNNSADSSTLLVESDLHDPRMAAVVSGHKVNTAMLCPSSLYADMALTIAKHMLKSNGMLHEKTGLDCRSMAIQRPLIVQPEATSQLLRVSAEAQWPKNEISLIFFSVSANGRKLAEHATCVVKVTQDQSWLTEWKRNAYLISSRIASLHKAVDTGGAHKLKRGLTYKLFASLVDYARDYQGMEQVILDSECLEATAEVKFQIDNQGFDWNPCWIDSLGHIAGFIMNGNDNICSQDQVFINHGWEAMRCGKAVEYGKTYTTYNRMQLEGGTMYVGDTYIFEGQQIVAVFEGVRFQGVNRSVLDHLLPGKTRAVTQQVASKPDASGHAGTGASAVLVKKRTSPALATKPAPITAKDQRSQLGKTSGIIKIILEEAQMDEDELDVDAEFADLGVDSLLSLTIASRLQDELGIEIPTSTFMDHPTIKAFISFIGGEESLGSSSAQSVASGEESYFTDATSVDGENVDSDTDIMTIIRTIISEETGTPLEDISSSSPLAELGLDSLLGLTIMGRLSEQVDVCLPTSLFVDSETLEVIEAALREAGLINKNGKRGYRAKSQDAASIKAMDTKPVTASQSSFDLNTPPHATSVLLQGSSRTAKKTLFLFPDGAGSATSYHALGNISSNVVVYGLNCPWLKTPADLKCSLEEYVAKFLIEVRRRQPTGPYHFGGASAGGILAYEAAQQLDRAGERVATLVLLDSPDPVGLENPNQRMYDFLDSMGMFGMSGKQAPQWLRPHFDAFLALLDAYEVKKFRGSSPPTTYIIYARDGMCKHESDPRPEVRPDDPREMLWLLNNRTDFSGAGWNSLVGKENLHVSVLGNVNHYTIMQAGPQMKELCARIARALQG
What is the function of this protein?
Non-reducing polyketide synthase; part of a gene cluster that mediates the biosynthesis of a yet unidentified natural product (Probable).  The first step in the pathway is performed by Preu4 that produces two major yellow-colored compounds which structures are not stable and hard to be characterized (PubMed:35602042).
What are the official names of this protein?
Non-reducing polyketide synthase Preu4, NR-PKS Preu4.
Protein: CDN5_RANCA
Sequence: GLLGMVGSLLGGLGL
What is the function of this protein?
Caeridins show neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Caeridin-5.
What are the subcellular locations of this protein?
Secreted.
Protein: SOL2_YEAST
Sequence: MTTTVPKIFAFHEFSDVAEAVADHVVHAQDGALAPKNERKHSVPNISMNALDMTREASCKSTASAAEGKSGSSGSGSGSSKPKKEKRFKIALSGGSLIEVLHEGLLKRDDVRWGDWDIYFADERLVPFSSNESNYGCAKRKILDLIDTAKYGTPKVYHIDESLIDDPQECADNYEKVLIRGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQDNLREKLAWVVPVENAPSGPSTRISLTIPVICHSHRVTFVVEGATKAPIIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALTDVLVTKKKYKFHQGLSI
What is the function of this protein?
May be involved in regulation of tRNA subcellular distribution.
What are the official names of this protein?
6-phosphogluconolactonase-like protein 2, Suppressor of LOS1.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_LACLA
Sequence: MSGKSPAQTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDENGVCTATEDYKDVAAVADQIGVPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMELGADYVATGHYAQVRTDENGIVHMLRGADNNKDQTYFLSQLTQEQLKKTMFPLGHLEKPEVRKIAEKAGLATAKKKDSTGICFIGEKNFKKFLGEYLPAQPGKMMTLDGIEMGNHAGLMYYTIGQRGGLGIGGQHGQLTSDPWFVVGKDLTTNTLYVGQGFHHEHLYSTSLDASDLSFTREMPETFDLHCTAKFRYRQEDTGVTIHVNGDKVTVDFDEPVRAITPGQAVVFYDGEECLGGAMIDVAYKAQKVMQYQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HARB_PYRFU
Sequence: MGELPIAPVDRLIRKAGAQRVSEQAAKVLAEHLEEKAIEIAKKAVDLAKHAGRKTVKVEDIKLAIKS
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.  Increases the resistance of DNA to thermal denaturation (in vitro).
What are the official names of this protein?
Archaeal histone B, Archaeal histone A2.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: YJN2_SCHPO
Sequence: MATKVEEINKLKKKNLHFRQCSADSLSNSSMQFDLSGLNTPVGELATSNLPSPAHPPFGELHQESRTSNSSAMHIENVVASRLMYNEVANGSFALEPKNILVVTKPRKHSLVYKTAEITKYILTIGTPETKVYVDMRLARSKRFSAHNIAKEANTDIDRIKYWNPYICLIKPSIFDLAITIGDNSTLLYTSWLFQKIGPPVLSFSDDDVPGFLTHFSLSNYQQHLYQVLTQNVSLRFCSRLQCSFHKYDEKTKQYSLASTTYSLDEILISRGEHPFISNLNVYNNSELMTVVQADGLVVATPTGSTNISANAGGSLVHPALNAILVTPVCPHTLSFRPIILPDYNVLNVEIPLDSRSSAFFSVDRHESVEMHRGDYLSIVTSHYPFTTIQNPGYQWTKVLEDKFNWNVRERQKPFSRKPSLSDVKDTSDDKFDITDNSYCREFSADIDG
What are the official names of this protein?
Uncharacterized kinase C24B10.02c.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSBI_CHAGL
Sequence: MLTLKIFVYTVVIFFVSLFIFGFLSNDPARNPGRKEN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CINAL_SHEPC
Sequence: MKLEMICTGEEVLSGQIVDTNAAWFASTMMEHGIEIQRRVTVGDRLEDLIAVFQERSLHADVILVNGGLGPTSDDMSAEAMAKAKGESLVENIEWRQQLEDWFTRNNREMPVSNLKQAMLPESAVMVDNPVGTACGFRVKLNRAWLFFTPGVPFELKHMVKEQFIPFIRDEFNLDAKVALKKLLTIGQGESALADKIEPLELPEGITIGYRSSMPHIEIKIFARGEKAIVLLPRVTGHVKMVLGTAVVAEDKATLAEEIHSRLLNSGLTLSVAESCTGGMITSQLVDFAGSSSYLHHGLVTYSNESKVRVLGVNPATLDDHGAVSIPTVEEMAKGARAILDSDFALATSGIAGPDGGTEDKPVGTVAIALATRNGVYSQMIKLPRRSRDLVRSLSAAVAYDMLRRELLAEAVIVDYQSIGRFSK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: SECA_CUTAK
Sequence: MNLMDRVLHAGEGKIIRRLNRIVGQVNSIEEDYVAMDDDELAGQTADFRQRLDNGESLDRLLPEAFATVREASKRVLGKRHFDVQIMGGAALHQCNIAEMKTGEGKTLVGLLPAYLEGLLGEGVHIVTVNDYLARVQSEQMGRVHRFLGLSISAILSDMPPMARKEAYKADVTYGTNNEFGFDYLRDNMASSLSECVQRGHHYAIVDEVDSILVDEARTPLIISGPAEENKQWYPEFAKIVSRLERDVDYEVDEKKRTVSVLGHGITVVEERLGIENLYESANTPLIGYLNNAIKAKELFHRDKDYVVVGGEVLIVDEHTGRTLAGRRYNEGLHQALEAKEHVEIKDEYQTLATITLQNYFRMYDKLAGMTGTAKTEESEFQKIYGLGVIPIPTNRPMIRKDQKDLIYRTEDAKFDAIIADVVERHEAGQPILIGTASVAKSELLSEKLKRAGVPHKVLNAKHHESEAAIVALAGRKGAVTVSTNMAGRGTDIILGGNPEFLTELDLREKGLDPLEDQDAYQTAWNNTLAKYEEQSQAEHNEVEGLGGLYVIGSERHESRRIDNQLRGRSGRQGDPGESRFYLSLQDELMRLFKPEVIDRAMVTLKMPEDMPIESKWVSRQIESAQKQVEAQNFEMRKNVLKYDDVMNRQRHVIYGDRRKVLEGADVETELRATTDRVVEAGVRKYAEGYSEDWDLEAMWNEIGTVYPVGLDLDEYADCQDVEELIEDFKADAQEAYDRRESELGEATMRQLEREVLLTVLDRKWREHLYEMDYLREGIGLRAMAQRDPLVEYQREGGDMFNSMMDSFKEEVVGFLFNLEIETGPQVGLVTDDGGNPVTADSVLPKVNRPRRALTYSAPDEQGEAETTSEDGQKPRGEGNRAARRSAASKKPKNRRNKKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: FTSK1_NEIMB
Sequence: MTEKSHKKTAKGRAGSPSPTSARNKKADNGARGNKVSERLKAVKELQKTETKKARPEHVVNLIGDALWLMGLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWIAAACVVLYKNFRLHAKQTENEAYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISWLEFLNGAGRAVQNRLSALSGKVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKIQVSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVKGSQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLAKMPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEKRYRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADLMMTERKAVEQQIARLAQKARAAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDEVHQVVNYVKSQAPADYIEGLLSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALENAGVVSSTDLNGSRKILAHKDHL
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK 1.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: VPR_HV2ST
Sequence: MTEAPTESPPEDRTPPREPGDEWVIETLREIKEALKHFDPRLLITLGNYIYARHGDTLEGARGLIRILQRALLLHFRAGCGRSRIGQPRGRNPLSAIPTPRGMR
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RDRP_AHV2H
Sequence: MSTLLIPQDTIAHTFDEAVASESNLRIDEVPENYLERFIHPSEPENFEFYSLRDSDIPSKRIPKNGIQVFENLKYHTNSKDNLYKDQPSSGPSPMRGVANIIREYFPQYLDDLRTWCRPKSSDDSIFNDFNHEQRITQPFTEERERRLLPLIDHFLGIKPYDIVHYCDTRFYPWKLSTRADYFHNHSRDRKAHAAKSHPDFATGPTKKSYFINSHLFFDRSTVHNIKEYGFPFRPTTDSARNETLLDLWFKKVPTELLVRSHISKRDNLKVRPVYNAPMIYIRIECMLFYPLLAQARKRDCCIMYGLETIRGGMNELERISNAFNSFLLIDWSRFDHLAPFTISNFFFKKWLPTKILIDHGYAQISNYHDHVHSFSAQAQSHGIPMISKEYQTPPEATVFAKKVLNLISFLERWYRDMVFVTPDGFAYRRTHAGVPSGILMTQFIDSFVNLTILLDGLIEFGFTDEEIKQLLVFIMGDDNVIFTPWTLLKLIEFFDWFAKYTLDRFGMVINISKSAVTSIRRKIEVLGYTNNYGFPTRSISKLVGQLAYPERHVTDADMCMRAIGFAYASCAQSETFHALCKKVFQYYFAKTSINERLILKGRKAELPGMFFAYPDVSEHIRLDHFPSLSEVRILLSKFQGYLKETPFGTIPTFSTPQTLRDQTQ
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome.
What are the official names of this protein?
RNA-directed RNA polymerase.
Protein: TDCB_STAAC
Sequence: MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQKEKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQQATKGYGAKVILKGKNFNETRLYMEELAKENGMTIVHPYDDKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTIADGCDVKVPGEQTYEVVKHLVDEFILVTEEEIEHAMKDLMQRAKIITEGAGALPTAAILSGKINNKWLEDKNVVALVSGGNVDLTRVSGVIEHGLNIADTSKGVVG
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
What are the official names of this protein?
L-threonine dehydratase catabolic TdcB, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: RL27_SHIBS
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: APAG_PHOPR
Sequence: MSANSPPTIKCNVVTHYIEEQSEPNNQRYVFSYTITIRNLGKGSAKLLSRYWLITDANGKRLVIEGEGVVGEQPEIKMNEEYTYTSGTIIETPLGVMQGHYVMGTEDGETFKAEVSPFRLAIPNILH
What are the official names of this protein?
Protein ApaG.
Protein: SYGB_EDWI9
Sequence: MTQQTFLVEIGTEELPPKALRSLAQAFADNFRTELDNAGLAHGDIEWFAAPRRLALKVAALNAAQPDREIEKRGPAIAQAFDAEGKPTKAAEGWARGCGISVDQAERLSTDKGEWLLYRALQKGQRAQDLLPALVASALSRLPIPKLMRWGDSDTQFVRPVHTVTLLLGSESIPATILGVPSDRVIRGHRFMGEAEFTLDSADQYPQILLERGKVIADYDARKALIKRDAEAAAARIGGVADLSDSLLEEVTSLVEWPVVLTARFEEKFLAVPAEALVYTMKGDQKYFPVYDAAGKLLPNFIFVANIDSKDAQQIIAGNEKVVRPRLADAEFFFKTDRKQRLEDNLPRLESVLFQQQLGSLRDKTDRITALAGWIAQQIGADVNMATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEEVAVALNEQYMPRFAGDALPTSLVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIVVEKKLPLDLLTLTQEAVRLYGDKLGNASVVDDVVEFMLGRFRAWYQEEGHAVDTIQAVLARRPTRPADFDARVRAVSHFRTLPEAATLAAANKRVSNILAKSGDVLAEQVQAVLLKEPAEIRLAANLITLQEKLAPLFADGRYQEALVELATLRQPVDDFFEQVMVMADDEQVRINRLTLLNKLRDLFLQVADISVLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAD_SALG2
Sequence: MSTYTRPVMLLLCGLLLLTLAIAVLNTLVPLWLAQANLPTWQVGMVSSSYFTGNLVGTLFTGYLIKRIGFNRSYYLASLIFAAGCVGLGGMVGFWSWMSWRFIAGIGCAMIWVVVESALMCSGTSHNRGRLLAAYMMAYYMGTFLGQLLVSKVSGELLHVLPWVTGMILAGILPLLFTRIVNQQTQARHSSSISAMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLKHQGMANASIGFWMAVLVSAGILGQWPMGRLADKFGRLLVLRVQVFVVILGSIAMLTQAAMAPALFILGAAGFKLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFAAMLMQNYSDNLLFIMIASVSFIYLLMLLRNAGQTPNPVAHI
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C71BS_ARATH
Sequence: MSVFLCFLCLLPLILIFLKNLKPSKWKLPPGPKKLPIIGNLHQRRELHPRNSRNLSEKYGPIVFLRYGFVPVVVISSKEAAEEVLKTHDLECCSRPETVGTRAISYNFKDIGFAPYGEDWRTMRKLSVVELFSSKKLQSFRYIREEENDLCVKKLSDLASRRSLVNLEKTLFTLVGSIVCRIGFGINLRECEFVDEDSIDDLVHKSEDVIRNSIFSDFFPGLMGRLIEWIFSERKRLNRLYSEVDTFFQNILDDHLKPGRESSDIIDVMIDMMKKQEKEGDSFKFTTDHLKGMISDIFLAGVGTSSTTLIWAMTELIRNPRVMKKVQDEIRTTLGDKKERITEEDLNQLHYFKLMVKEIFRLHPAAPLLLPRETLSHVKIQGYDIPAKTQIMINAYAIARDPKLWTNPDEFNPDRFLDSSIDYRGLNFELLPFGSGRRICPGMTMGIAIVELGLLNLLYFFDWGLPEKEEAKEIITGNEVALDLVQVFLH
What are the official names of this protein?
Cytochrome P450 71B28.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FBSB_SYNS9
Sequence: MDQSLIQEILEIVEQAAIASATLSGKGLKDEADALAVDAMRKRMNQINMQGKIVIGEGERDEAPMLYIGEEVGTGNGPGVDFAVDPCEGTNLCAYSQRGSMAVLAASDRGGLFNAPDFYMKKLAAPPAAKGKVDIRKSATENIKILSECLGLAPDELTIVVMDRARHKDLIAEIRATGARIQPISDGDVQAAIACGFAGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQTSEWADMTKEGNLQRLAEMGITDPDKVYEASELACGEHVVFAGSGITDGLLFNGVKFEADCTRTSSLVISNMNNTCSFTTTIHMKDGAQSIALN
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: ITBP2_HUMAN
Sequence: MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE
What is the function of this protein?
May play a role during maturation and/or organization of muscles cells.
What are the official names of this protein?
Integrin beta-1-binding protein 2, Melusin.
Protein: RISB_YERPP
Sequence: MNVIEGVVATPNARVAIAIARFNNFINDSLLDGAIDALKRIGQVSDDNITVVWVPGAYELPLVANVLAKTNRYDAVIALGTVIRGGTAHFEYVAGEASSGLSSVAMNSDIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVIKAIKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.