PharMolix/UniProtQA huggingface dataset:
Protein: CIAO1_HUMAN
Sequence: MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQRPEGL
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:17937914, PubMed:23891004).  As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors.  The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins.  CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (PubMed:23891004).  Seems to specifically modulate the transactivation activity of WT1 (PubMed:9556563).  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (PubMed:20797633).
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSD_ECOHS
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLDN_HUMAN
Sequence: MARGAEGGRGDAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSSALRALEAQRGREQREDSALRSFLAELSRAPRGASAPPQDPASSARNKRSHSGEPAPHIRAESHDMLMMMTYSMVPIRVMVDLCNSTKGICLTGPSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAESMITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTFIHLPYYFHGCGHVVYNNSLYYHKGGSNTLVRFEFGQETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQHVNTTYPKSKAGNAFIARGILYVTDTKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLMLYPVQFLSTTLNQ
What is the function of this protein?
Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons.  Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC.  Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons.  During development, nodes of Ranvier are formed by the fusion of two heminodes.  Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters.  Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
What are the official names of this protein?
Gliomedin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cell projection, axon. Note=Detected at the nodes of Ranvier. Detected at immature heminodes. SUBCELLULAR LOCATION: [Gliomedin shedded ectodomain]: Secreted. Secreted, extracellular space, extracellular matrix. Note=Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier.
Protein: FAS1_YARLI
Sequence: MYPTTGVNTPQSAASLRPLVLSHGQTEHSLLVPTSLYINCTTLRDQFYASLPPATEDKADDDEPSSSTELLAAFLGFTAKTVEEEPGPYDDVLSLVLNEFETRYLRGNDIHAVASSLLQDEDVPTTVGKIKRVIRAYYAARIACNRPIKAHSSALFRAASEDSDNVSLYAIFGGQGNTEDYFEELREIYDIYQGLVGDFIRECGAQLLALSRDHIAAEKIYTKGFDIVKWLEHPETIPDFEYLISAPISVPIIGVIQLAHYAVTCRVLGLNPGQVRDNLKGATGHSQGLITAIAISASDSWDEFYNSASRILKIFFFIGVRVQQAYPSTFLPPSTLEDSVKQGEGKPTPMLSIRDLSLNQVQEFVDATNLHLPEDKQIVVSLINGPRNVVVTGPPQSLYGLCLVLRKQKAETGLDQSRVPHSQRKLKFTHRFLPITSPFHSYLLEKSTDLIINDLESSGVEFVSSELKVPVYDTFDGSVLSQLPKGIVSRLVNLITHLPVKWEKATQFQASHIVDFGPGGASGLGLLTHKNKDGTGVRTILAGVIDQPLEFGFKQELFDRQESSIVFAQNWAKEFSPKLVKISSTNEVYVDTKFSRLTGRAPIMVAGMTPTTVNPKFVAATMNSGYHIELGGGGYFAPGMMTKALEHIEKNTPPGSGITINLIYVNPRLIQWGIPLIQELRQKGFPIEGLTIGAGVPSLEVANEWIQDLGVKHIAFKPGSIEAISSVIRIAKANPDFPIILQWTGGRGGGHHSFEDFHAPILQMYSKIRRCSNIVLIAGSGFGASTDSYPYLTGSWSRDFDYPPMPFDGILVGSRVMVAKEAFTSLGAKQLIVDSPGVEDSEWEKTYDKPTGGVITVLSEMGEPIHKLATRGVLFWHEMDKTVFSLPKKKRLEVLKSKRAYIIKRLNDDFQKTWFAKNAQGQVCDLEDLTYAEVIQRLVDLMYVKKESRWIDVTLRNLAGTFIRRVEERFSTETGASSVLQSFSELDSEPEKVVERVFELFPASTTQIINAQDKDHFLMLCLNPMQKPVPFIPVLDDNFEFFFKKDSLWQCEDLAAVVDEDVGRICILQGPVAVKHSKIVNEPVKEILDSMHEGHIKQLLEDGEYAGNMANIPQVECFGGKPAQNFGDVALDSVMVLDDLNKTVFKIETGTSALPSAADWFSLLAGDKNSWRQVFLSTDTIVQTTKMISNPLHRLLEPIAGLQVEIEHPDEPENTVISAFEPINGKVTKVLELRKGAGDVISLQLIEARGVDRVPVALPLEFKYQPQIGYAPIVEVMTDRNTRIKEFYWKLWFGQDSKFEIDTDITEEIIGDDVTISGKAIADFVHAVGNKGEAFVGRSTSAGTVFAPMDFAIVLGWKAIIKAIFPRAIDADILRLVHLSNGFKMMPGADPLQMGDVVSATAKIDTVKNSATGKTVAVRGLLTRDGKPVMEVVSEFFYRGEFSDFQNTFERREEVPMQLTLKDAKAVAILCSKEWFEYNGDDTKDLEGKTIVFRNSSFIKYKNETVFSSVHTTGKVLMELPSKEVIEIATVNYQAGESHGNPVIDYLERNGTTIEQPVEFEKPIPLSKADDLLSFKAPSSNEPYAGVSGDYNPIHVSRAFASYASLPGTITHGMYSSAAVRSLIEVWAAENNVSRVRAFSCQFQGMVLPNDEIVTRLEHVGMINGRKIIKVTSTNRETEAVVLSGEAEVEQPISTFVFTGQGSQEQGMGMDLYASSEVAKKVWDKADEHFLQNYGFSIIKIVVENPKELDIHFGGPKGKKIRDNYISMMFETIDEKTGNLISEKIFKEIDETTDSFTFKSPTGLLSATQFTQPALTLMEKASFEDMKAKGLVPVDATFAGHSLGEYSALASLGDVMPIESLVDVVFYRGMTMQVAVPRDAQGRSNYGMCAVNPSRISTTFNDAALRFVVDHISEQTKWLLEIVNYNVENSQYVTAGDLRALDTLTNVLNVLKLEKINIDKLLESLPLEKVKEHLSEIVTEVAKKSVAKPQPIELERGFAVIPLKGISVPFHSSYLRNGVKPFQNFLVKKVPKNAVKPANLIGKYIPNLTAKPFEITKEYFEEVYKLTGSEKVKSIINNWESYESKQ
What is the function of this protein?
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH.  The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
What are the official names of this protein?
Fatty acid synthase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the fungal fatty acid synthetase subunit beta family.
Protein: RIMK1_SHESR
Sequence: MRIAILSQGPELYSTKRLVEAATLRGHEVKVINPLECYMNINMRQSSIHIGGEELPPFDAVIPRIGASITFYGSAVLRQFEMMGVYALNDSVGISRSRDKLRSMQLMSRRGIGLPITGFANKPSDIPDLIDMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFMGLKANIMVQEYIKEANGADIRCFVLGDKVIAAMKRQAMPGEFRSNLHRGGTASLVKLTPEERSVAIRAAKTMGLNVAGVDLLRSNHGPVVMEVNSSPGLEGIEGATAKDVAGAIIEFVEKNALKAKKPTQA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: ENTD_ECO57
Sequence: MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQPIGVDIEEIFSAQTATELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEIQTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms.  Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.
What are the official names of this protein?
Enterobactin synthase component D, 4'-phosphopantetheinyl transferase EntD, Enterochelin synthase D.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. EntD family.
What are the subcellular locations of this protein?
Membrane.
Protein: ARCC_LENHI
Sequence: MGRKIVVALGGNAILSKDASAAAQQQALMDTAKHLVKFIENGDQLIISHGNGPQVGNLLLQQSAGSTEENPAMPLDTAVAMTQGSIGYWMQNAMNQVLKEKGLNKTVATVVTQVEVSADDPAFTNPTKPIGPFMSKDEADLAKKENPDFTFVEDAGRGYRRVVPSPKPIGVVETDAVNTLVDAGIVPISVGGGGIPVVADGNQLLGREAVIDKDFASEKLAELVGADALIILTAVPNIYVNFNKPNQKKLEHVSVNDLETYISEKQFAPGSMLPKVQAAIDFVKATGNEAVVTALDNIEGFVNEGSGTVITKKVRQQA
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_AQUPY
Sequence: MIQRQTYLNVADNSGAKKVQVIGIPYAPRKYATLRDVVTVTVKEALPQGNAKKGKIYRAIIVRTAKEVRRPDGSYIKFDDNACVLLNQYGEPLGTRVLGPIAREVRNKGFTKIASLAPEVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL29_WOLPM
Sequence: MDIADIESRSSQELHEILVNLRKEFVNLVFQKKLAQCNNISRFSLIRKSIARILTTLNKRRREEKNA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ACSA_XANP2
Sequence: MSDKIYYVPSEWAQKAYVDDAHYQSMYAASVNDPHAFWGEHGKRIDWFTPYTKVKNTSFDPGHVSIKWFEDGITNVAYNCVDRHLETRGDQVAIIWEGDSPDESRNITYRELSSEVNKLANVLRNRGVEKGDRVTIYLPMIPEAAFAMLACARLGAIHSIVFGGFSPDSLAGRVADCGSKCIITADEGLRGGRKVPLKANVDAAIAQINGGVDHVIVVRRTGGKVDMLPGRDVYYDEATAMVTDECPAEHVNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYIFDYHPGDIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGIPNYPSVSRFWDVIDKHKVNIFYTAPTAIRSLMQAGEEPVKRTSRSSLRLLGSVGEPINPEAWEWYYRVVGEERCPIVDTWWQTETGGILITPLPGATKLKPGSATRPFFGVMPEVVDAEGKVLEGACEGNLVIADSWPGQMRTVYGDHERFEQTYFSTYPGKYFTGDGCRRDADGFYWITGRVDDVINVSGHRMGTAEVESALVAHPKVSEAAVVGFPHDIKGQGIYAYVTLMDGEEPTEELRKELVGWVRREIGPIASPDLIQFAPGLPKTRSGKIMRRILRKIAEDQFESLGDTSTLADPGVVEDLIHNRQNKRDAAA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GLPK_SHIDS
Sequence: MTEKKYIVALDQGTTSSRAVVMNHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: YWAC_BACSU
Sequence: MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVKSFESIVNKLMRKGCEITTKEMKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVKDYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTIAMDFWASLEHKIYYKLNNDVPKQLTDELKEAAEIAHYLDEKMLGIKKEVD
What is the function of this protein?
Functions as a (p)ppGpp synthase; GDP can be used instead of GTP, resulting in an increase of (p)ppGpp synthesis (PubMed:18067544).  Overexpression in relA mutants (triple relA-yjbM-ywaC deletions and single relA deletions) leads to growth arrest; GTP levels fall drastically, various guanine-related nucleotides are synthesized (ppGp or pGpp), the cellular transcriptional profile changes dramatically and 70S ribosome dimerization occurs (PubMed:22950019).  Overexpression in the presence of a wild-type relA gene does not have these effects (PubMed:22950019).  In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  activities in response to changes in nutritional abundance.  YwaC has probably a minor role in stringent response (PubMed:18067544).
What are the official names of this protein?
GTP pyrophosphokinase YwaC, (p)ppGpp synthase YwaC, Small alarmone synthase 2, SAS 2.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: HFQ_BURM9
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: FGF18_RAT
Sequence: MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQTELQKPFKYTTVTKRSRRIRPTHPG
What is the function of this protein?
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration.  Required for normal ossification and bone development.  Stimulates hepatic and intestinal proliferation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 18, FGF-18.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: MYL5_FELCA
Sequence: MASRKTKKKEGGGLRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNIKDDELDAMLKEASGPINFTMFLNMFGAKLTGTDAEETILNAFKMLDPEGKGSINKDYIKRLLMSQADKMTAEEVDQMFQFATIDAAGNLDYKALSYVLTHGEEKEE
What are the official names of this protein?
Myosin light chain 5, Myosin regulatory light chain 5, Superfast myosin regulatory light chain 2, MYLC2, MyLC-2.
Protein: CYNS_USTMA
Sequence: MSSSNIQRPKILSTLPSIFSYLHDAKVRSKMTFADIAAEMDRDEWYVAAIFYGQAKPDQADIVKLSAALNLQQRYLDEAFGPDFFPHRGLGEFPPQDPVLYRLYEVLVVYGYPLKHMIHEKFGDGIMSAIDFEGHVEKVKGSSNEDRVKITLNGKFLPYRRW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: GLN1B_ECO57
Sequence: MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWNSSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_HAEIN
Sequence: MQTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSIQSLLSGPMGGDQQLGGLIAEKKIDMMIFFWXPMNAAPHEPDVKALMRIATVWNIPVAINQSSADFLLTSVLFEQDVEIDVPDYEGYLKERLA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: PUR9_ECO81
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEGSLTLATRFNLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAVSNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLICGQWGERAPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ADDB_ANOFW
Sequence: MSVRFIIGRSGSGKTTMCLKEMIDQLAQKPDGDPIIYLVPEQMTFQSEYALMNGSLKGMIRAQVFSFTRLAWRILQETGGMSRHHLTQTGVHMLLRKIVEQQKEQLTLFRKAADKRGFIEQLEQMLTEYKRYCVTPATLKQTEEQLRRHATANETVLADKLKDTAMIFEQFEQQMAHHYVDSEDYLRLLAEKIRHSSYMKRARIYMDGFYEFTPQEYMVIEQLFIHCPHVTVALTLDAPYEQLPDDLHVFRNTWRTYAQLRDIALQNGVPIEKVEQLRHNVRHKHEELRHLEAHYDDRPVCKWEKQTEAIIIGEATTRRAEIEGIAREIIRLVRDEGYRYRDIALLIRNVGDYRNVLKTVFADYRIPYFIDEKEPMLDHPFIEWLRASMEAVRTNFRYEAVFRAVKTDFFFHLDQPVHDMRMAMDQLENYVLAFGIQGDKWTEHWTYRKYKGLEGVHAPQTDEEKRYEQQLNEWRKLVISPLLVLQKRLKQAKTGREQCEALYAYAEHLQIPQKLERLRDEAEERGDLSVARHHEQVWQAFIDLLDQYVEILGDETLSLETFLTIIETGFESLQFSLVPPATDQVLIAHFDRSRLSNIRCTFLVGVNEGVIPMRKNDDGMLSETDRELLYHYSLHVAPASRERMLDEPFLLYLALVSSSERLYVTYALSNEQEKTLLPSMFIKRLTDMFPNVTKMQWGTDPFLLPLQQQLAYVTNDVATLGPLVQQLEAWKRQYAIEPMWWDVYNAYVQHEQWKERIAVVVRALFYENRAKRLNKQLAKELYGKKVKASISRMETFNRCPFAHFAAHGLKLKERTVFQLKAPDMGQLFHQALKVIADRLRQEQLPWSQLSKQQCEQLSYEAVEQIAPYIQQEVLLSTHRYRYMKKKLQTIMTKATTVLSEHAKRSGFVPIGVELGFGDGEPLPPLTFTLSDGTVLQFVGRIDRVDQAMSEQGVLLRVIDYKSKQKTLDLTEVYYGLALQMLAYLDIVLEYAEKLVGTSAFPAGVLYFPIHNPMMKVNEWLDEHELEKKFLEQFKMGGYVLADEKTVRLMDEHVEPGTSSLIIPVRLNKNGTFAQHSKVLTEQQFTMLRQHVRRFIVDVGEQMIEGVTHIAPYKQKNKTACQYCEFRDVCQFDEGVDAEQYRVLTPKNIDEWLKG
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: TRE1_PSEPG
Sequence: MDLLANVPSWSDIERSLDQKFSAVNQSIHQGLQSANDSWHGFSRRVSDGAGQAYGYLGGHRIDNVQQALAMSYPIFQEDLKRKWASIGIEQILPVLLQLVKEVSMILGGSIAVGSAAGGAIGALAFGVGAAPGAVAGAGIGLEVGNLILLALGLSAIAEYFIKGLPVCLATLQEGIATAWNAEEGVKPAGLDPTGGSVAVIQERTERAARQLARGQEQLVLLLLMAIVTYLLRGQMKAGIMGSMENIATRSAKLQADIANKQFGAWLAKNEAKLLAHPDLQIKGPTPVKKPEPLQPARQPEKASAPKPVAKPAVMSLREAVGNQTADRWISTGRRIADFTDPKRSALLTDDQIGALHGYTTNEGYQWINPALRGQTPLSPQMEAFVTHANEGLAKLPSYTLGDTFRGTTLPEDVMSRMQVGLPTSDAAFLSTSADRALAFNGNVKMTLQGVTGKDISFLSGHREAEVLFGPGTRFNVVDRVDNGSVTQFILKEIP
What is the function of this protein?
Toxic component of a contact-dependent interbacterial competition system (also called effector-immunity systems).  Acts by ADP-ribosylating a number of target proteins in target cells; E. coli target proteins include FtsZ, EFTu, RNase E, Fis, YegQ, GuaB and IF2.
What are the official names of this protein?
NAD(+)--protein-arginine ADP-ribosyltransferase Tre1, Effector protein Tre1, Tre1-Pp, NAD(+)--protein-arginine ADP-ribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Probably delivered to target cells by a type 6 secretion system (T6SS).
Protein: Y6445_DICDI
Sequence: MESTPPRFGLDCRNRNKKDVNIRKQKEILKVDKLKKLEIKKLEDQKKLKEQEEKHRLTLIRLANAPPQTNSINNNNNNNNNIKTNRPPLIYGEDKDKKSLFPEPQDYDVDEPTYETSFCVKLGPNGVFQHELRFTNANARENSDIQKAIELSLKQTDVVIVKNPNDDIENDFVVFNEQPDEREKELEHWELMDECSSSLVNFVTTPYNFSEIEFPRLASTCSTQMLKKNLNQNNPWLNSKSLIANISQK
What are the official names of this protein?
Uncharacterized protein DDB_G0280211.
Protein: HPS_STAAN
Sequence: MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAVKHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGGIKPDTIKDIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: ACCA_CHESB
Sequence: MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQKAQVARHPDRPHCMDYVRALFTDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGNDTHSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDTAGAYPGIGAEERGQAEAIARSTSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTRAKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGDFREQRREKFLAIGRSL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_YERPA
Sequence: MSLDIDQIALHQLIKRDEQTLDVVLRDSLLPTNAVVEEMMAELHRVYSAKSKAYGLFNEQSELADALKRSRKGDEDFLSFSRAATGRLRDELAKYPFAEGGVVLFCQYRYLAVEYLLISVLSSCHSMRVNEQLDLSTTHYLDINRADIVARIDLTEWETNPESTRYLTFLKGRVGRKVSDFFMDFLSAAEGLDTKAQNRGLLQAVDDYCADAELGKNERQAYRQQVYSYCNEQLQAGEEIALQVLAQELPKLGEKDFQQFSAEQGYALEESFPADRGTLRQLTKFAGSGGGLSINFDALLLDERIFWDAATDTLTIKGTPPNLRDQLQRRAGSK
What are the official names of this protein?
Nucleoid-associated protein YPA_0980.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GCST_FRATO
Sequence: MLKTPLYESHIAANAKMIDFSGWSMPINYGSQIQEHNNVREDCGIFDVSHMLAVDIQGSEAEKFLRYLLANDVAKLQENKAQYGCMLNHDAGIVDDLITYKVTDEHFRIVVNAGNRESDVAWFNQNAQNFDVAITPQTDLAIVAVQGPKAVAVIKRVVTKEIAAEIEALLPFSFKFFSKWMVARTGYTGEDGFEVILPATQVKKFWDSLLENGAQPAGLGARDTLRLEAGMHLYGADMDTSTTPLERGLGWSVDLSDEHRDFIGKKAYLAKKAQGVDTKWVGVVLKTKGVLRAGQEIDFDNGEKGYITSGSFSPTLKVAIGLAYVPKQADNPVVNIRGKELEVELVKPKFVKNGKSLI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.