PharMolix/UniProtQA huggingface dataset:
Protein: SPD1_TRICX
Sequence: QGAGAAAAAAGGAGQGGYGGLGGQGAGQGGYGGLGGQGAGQGAGAAAAAAAGGAGQGGYGGLGSQGAGRGGQGAGAAAAAAGGAGQGGYGGLGSQGAGRGGLGGQGAGAAAAAAAGGAGQGGYGGLGNQGAGRGGQGAAAAAAGGAGQGGYGGLGSQGAGRGGLGGQGAGAAAAAAGGAGQGGYGGLGGQGAGQGGYGGLGSQGAGRGGLGGQGAGAAAAAAAGGAGQGGLGGQGAGQGAGASAAAAGGAGQGGYGGLGSQGAGRGGEGAGAAAAAAGGAGQGGYGGLGGQGAGQGGYGGLGSQGAGRGGLGGQGAGAAAAGGAGQGGLGGQGAGQGAGAAAAAAGGAGQGGYGGLGSQGAGRGGLGGQGAGAVAAAAAGGAGQGGYGGLGSQGAGRGGQGAGAAAAAAGGAGQRGYGGLGNQGAGRGGLGGQGAGAAAAAAAGGAGQGGYGGLGNQGAGRGGQGAAAAAGGAGQGGYGGLGSQGAGRGGQGAGAAAAAAVGAGQEGIRGQGAGQGGYGGLGSQGSGRGGLGGQGAGAAAAAAGGAGQGGLGGQGAGQGAGAAAAAAGGVRQGGYGGLGSQGAGRGGQGAGAAAAAAGGAGQGGYGGLGGQGVGRGGLGGQGAGAAAAGGAGQGGYGGVGSGASAASAAASRLSSPQASSRVSSAVSNLVASGPTNSAALSSTISNVVSQIGASNPGLSGCDVLIQALLEVVSALIQILGSSSIGQVNYGSAGQATQIVGQSVYQALG
What is the function of this protein?
Spiders' major ampullate silk possesses unique characteristics of strength and elasticity.  Fibroin consists of pseudocrystalline regions of antiparallel beta-sheet interspersed with elastic amorphous segments.
What are the official names of this protein?
Spidroin-1, Dragline silk fibroin 1.
What is the protein family that this protein belongs to?
Belongs to the silk fibroin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: Y1515_STRP7
Sequence: MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SP70585_1515.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_BURM9
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLTGPMIRGSGIAWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRKNPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS14_SYNS3
Sequence: MAKKSMIARDVKRKKMVERFSDRRAALMAAFHAAKDPMERLEIHRKIQGLPRNSAPNRVRNRCWATGKPRGVYRDFGLCRNQLRERAHKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: AROA_STRZT
Sequence: MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILRGEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVLAGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHYELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDGKKIIVQGPQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKLEITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAEELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAIAALLVADGEVELDRAEAINTSYPSFFDDLESLIHG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT2_SODGM
Sequence: MKSLKPGIGLMCIIALYYLLPLSFRSLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPSVGYWINNLSQWAFGHTNFAVHFGSAFSIALTALMVYWLALRLWQDRWLGLTAAAIYSSCLLVYSIGTYAVLDPMIALWLAAAMCAFWQAVQAPRGWRKGLGYLALGIACGLGFMTKGFLALAVPVLSVLPWVIAQKRWKEVFIYGPLALLGAVATSLPWVIAIARREPDFWHYFIWVEHVQRFAEDNAQHKAPFWYYLPVLLAGTLPWLGLLPGALRRAWRERQTQSGAFYLLGWVVMPLLFFSLSKGKLPTYILPSFAPLALLMARYAATCGGRALKVNGVLNLLFGLLCVITVASVLAPWGLAQHPLFVQNEVRKVLLGVLGFLVWAAVGGLTLRAPTVCWRWAALCPLGIALLVGQAIPQQVIDAKQPQSFIQTVRPQLEKSRFIFANSVGVAAGLAWELQRSDISLFELQGELAYGLSYPDAADRFIREEDFSDWLRERCKEGSVALVVLLPDGETQISHLPRADETYRRGRLVLLAYHQRRP
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2, 4-amino-4-deoxy-L-arabinose lipid A transferase 2, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALVOL_POLAE
Sequence: GVCDMADLA
What is the function of this protein?
Antifungal activity.  Inhibits mycelial growth of F. cinera, F. oxysporum, M. arachidicola and P. piricola.  Lacks protease, ribonuclease, deoxyribonuclease and hemagglutinating activity.
What are the official names of this protein?
Alveolarin.
Protein: NPD_ECO57
Sequence: MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQVLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL
What is the function of this protein?
NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins.  Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_DESAL
Sequence: MKRTFQPSKIKRARTHGFLKRMSTKAGRRIIKRRRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LGT_LIGS1
Sequence: MNFLGVINPVALQLGPFQIRWYGIIIASAVILAVYLSVLEGRKQNILDDDIYDLLLYSLPVAIICARIYYVVFEWSYYSHHLSETYRIWDGGIAIYGALIGAVIVILIFCRRRNIPTWTLLDVIAPTVILAQGIGRWGNFMNQEAHGVATTLGFLKSLHLPKFIINQMYIDGTYYQPTFLYESLWDISGFVVLIILRRQKKLLKSGEVVLSYIIWYSFGRFFIEGMRTDSLMLGSLRVSQWLSLILFISAIAAIFYRRYNDPLLKWYTE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OFT28_ARATH
Sequence: MSVVGAINPVPIAPTTRRRVGDSLDVISERPSNSSDYCNTINQPIVGSTDLDGGDATGQDSSPSSESSASSTGSHYHHDHYHRFYSHPVIRYLLLRKFWIPFYGGASTVVIGQGFRSGRNVGRRILGLLMLLVVASVFLRVYLMGGVRVVDHARLKEFVVVRTLRDDWSMAQREVAENQASSQPMRVLEKLPIPEIWQKPESGNYRQCVTRPKNYTRLQRQTNGYLVVHANGGLNQMRTGICDMVAVAKIMNATLVLPLLDHESFWTDPSTFKDIFDWRNFMNVLKHDVDIVEYLPPQYAAMKPLLKAPVSWSKASYYRSEMLPLLKRHKVLKFTLTDSRLANNGLPPSIQRLRCRANYQALLYTKEIEDLGKILVNRLRNNTEPYIALHLRYEKDMLAFTGCNHNLTTEEAEELRIMRYSVKHWKEKEIDSRERRIQGGCPMSPREAAIFLKAMGYPSSTTVYIVAGEIYGSESMDAFRAEYPNVFSHSTLATEEELEPFSQYQNRLAALDYIVALESDVFVYTYDGNMAKAVQGHRKFEGFRKSINPDRLNFVRLIDHFDEGIISWEEFSSEVKRLNRDRIGAAYGRLPAALPRLEENFYANPQPDCICNKSHPEQLRKQSSLRTDSKSWKKSALR
What are the official names of this protein?
O-fucosyltransferase 28, O-FucT-28, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: XYLA_RHIME
Sequence: MSTGFFGDIAKIKYEGPESTNPLAFRHYNPDDVVLGKRMEDHLRFAVAYWHTFVWPGGDPFGGQTFERPWFKDSMEAAKLKADVAFEFFQLLGVPYYCFHDADVRPEGRNFAENTSNLNAIVDYFAGKQGETGVKLLWGTANLFSNRRFMAGAATNPDPDVFAFAAATVKTCIDATQRLDGENYVLWGGREGYETLLNTDLKRELDQLGRFLNLVVEYKHRIGFKGTILIEPKPQEPTKHQYDYDVATVYGFLKRYGLENEVKVNIEQGHAILAGHSFEHELALANALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYHVLAGGGFKTGGTNFDAKLRRQSIDPEDLLIGHIGGMDCCARGLKAAAKMIEDKALSAPLEARYAGWNVPEAKKMLDGGFSLEEIEAWVLKSDVNPQPKSGRQELLENVVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_PSEFS
Sequence: MISDESDNFNPRDPRPADAGKPSKNEKRRAARQLATQALYQRQIAGASLNEIEAQFRVDNDFTFADLPYFHDILHGVHAHLTEIDAALAPCLDLTIDELDPVELCVMRLSAWELLYRVDVPYRVVINEGIELAKVYGSTDGHKFVNGVLDKLAPRLREAEVKAYKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ANDP_DROSE
Sequence: MKYFVVLVVLALILAITVDPSDAVFIDILDKMENAIHKAAQAGIGLAKPIENMILPK
What is the function of this protein?
Male-specific peptide with moderate activity against Gram-positive bacteria.
What are the official names of this protein?
Andropin.
What is the protein family that this protein belongs to?
Belongs to the andropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_BRASB
Sequence: MFKVRVIPCLDVKDGRVVKGVNFVNLRDAGDPVEAAIAYDAAGADELCFLDITATHENRGIMLDVVRRTAEACFMPVTVGGGVRTIDDIKTLLRSGADKVSINSAAVARREFVKEAAEKFGEQCIVVAIDAKSVARPGGGSRWEIFTHGGRKSTGIDALEYAQEVVSLGAGEILLTSMDRDGTRQGFDIPLTRAVADSVPVPVIASGGVGNLDHLVDGIRQGRATAVLAASIFHFGEFTIRQAKEHMVRQGLPMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCH2_RAT
Sequence: MDDAVGDLKQALPCVAESPAVHVEVLQRSGSTAKKEDIKQSVYRLLKRHNIVFGDYVWTEFDEPFLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAHV
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.  Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.  In males, required for efficient synapsis of the sex chromosomes and for sex body formation.  Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes.  Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes.  Plays a role in mitotic spindle assembly checkpoint (SAC) activation (By similarity).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: CCME_PECCP
Sequence: MSAPRKTRLYAILAVICGAVLTVALTLYALSSNIDLFYTPSEILYGKNETQEKPAIGQRLRVGGMVMPGSVRRDSQSLEVRFTVYDAQGSVEVTYNGMLPDLFREGQGVVAQGILDTDDHIMAKEVLARHDENYTPPEIKAAMEGQHGHAPAAVTEGKRL
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: EXP17_ARATH
Sequence: MTKIFSLLVAMIFSTMFFMKISSVSAGWLQAHATFYGGSDASGTMGGACGYGNLYTDGYKTNTAALSTALFNDGKSCGGCYQILCDATKVPQWCLKGKSITITATNFCPPNFAQASDNGGWCNPPRPHFDMAQPAFLTIAKYKAGIVPILYKKVGCRRSGGMRFTINGRNYFELVLISNVAGGGEISKVWIKGSKSNKWETMSRNWGANYQSNTYLNGQSLSFKVQLSDGSIKAALNVVPSNWRFGQSFKSNVNF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).  Target of the transcriptional activator LBD18.  Regulated by LBD18 to promote lateral root formation (PubMed:23872272).
What are the official names of this protein?
Putative expansin-A17, AtEXPA17, Alpha-expansin-17, At-EXP17, AtEx17, Ath-ExpAlpha-1.13.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: LAMB_ECOSM
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGNANTNTNFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: EFNB1_CHICK
Sequence: MARPRGGRWLLGVLLALCRLAAPLAKSLEPVSWSAGNPKFMSGKGLVIYPEIGDKLDIICPKAEPSKPYDYYKLYLVKKDQADACSTVMDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKRQQDYFITSTSNGTLDGLENREGGVCQTRSMKIVMKVGQDPNAVIPEQLTTSRPSKEADNTVKIVTQSPRHKVPTVEEPGKPGSVNQNGQETQGPSDGFLSSKVAVFAAIGAGCVIFILIIIFLVVLLIKIRKRHRKHTQQRAAALSLSTLASPKCSGNAGSEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
What is the function of this protein?
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
What are the official names of this protein?
Ephrin-B1, CEK5 ligand, CEK5-L.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SEPF_COPPD
Sequence: MAEGGFWKKLTNFFTASEEDEDIIEEDYMDEGYEAEEGTGFVPVQTRAVPVGSTIWVYQPSSFSFDVDSSFIGARIKDGYIIILNLQDLDDLSAQRLIDFVSGALYSVEGKLKAISSSVFLLVPKNVRVESFNEGFGTE
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RK14_MARPO
Sequence: MIQPQTYLNVADNSGARKLMCIRVIGTSNRKYANIGDIIIAVVKEAVPNMPIKKSEIVRAVIVRTCKEFKRNNGSIIKFDDNAAVVINQEGNPKGTRVFGPIARELRESNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TTCA_HAES1
Sequence: MNLNIITEKDKKQSYNLNKLQKRLRRNVGNAIADFNMIENGDKVMVCLSGGKDSYTLLDILLNLRLNAPIHFDIVAVNLDQKQPGFPEHILPEYLKSISVDYKIVAENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDMLETLFLNMFYGGKLKSMPPKLISDDGKQIVIRPLAYCKEKDIEKYAVAKQFPIIPCNLCGSQPNLQRQVVKEMLQKWDRQYPGRIETMFSAIQNIVPSHLCDSNLFDFKRIRHGKIPEGIEGDIAFDKEAFSPTPLVQENDEKIDFIQGEMISFKEVN
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_DEIRA
Sequence: MTDFSASPDLQDPTTHAGFVAIVGKPNVGKSTLLNAFLGTKVAPTSPRPQTTRRGVRGIYTLDNRQLIFVDTPGLHKPKDALGKYMNSEVHSALSDVDAVVWVVDLRHPPTDEDRLVANSVRDLPKPLFLVGNKTDAAKYPEEAMKLYGALLEGRGSDLPVSETMLSAQNSVNAVATLREQLLEVLPENPFFFPQGAASDQSREMWAAEIIREEAMKKLRDELPYAVATRVNRWTEREDGLQRIEGEIIVEKNAHKGMVIGAGGKQLREIGQAARKQLEVFLNHKVYLGLEVIVIPGWREDEEALRELGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: API5_PONAB
Sequence: MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRASEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLGNFNYERSLQGK
What is the function of this protein?
Antiapoptotic factor that may have a role in protein assembly.  Negatively regulates ACIN1.  By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation.  Also known to efficiently suppress E2F1-induced apoptosis (By similarity).
What are the official names of this protein?
Apoptosis inhibitor 5, API-5.
What is the protein family that this protein belongs to?
Belongs to the API5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear.
Protein: RECF_MICAN
Sequence: MYLEHLHLHSFRNYAEQVLKFESKKTILLGNNAQGKSNLLEAIELLATLKSHRVSKDRDLVLESDSEARIFARVNRLYGASELSLILRSSGRRTVIRDRQPLRRHLDFLGVINAVQFSSLDLDLVRGGPEARRDWLDTLLIQLEPLYVHILQQYNQVLRQRNALLKEIRKQELEGKVYGDLSQLKLWDLQLAETGSRVTRRRARVLQRLIPLAQKWHESISGKTELLELQYIPNVPWVEDDVNGVQRAFLDKIETRRLAEKQLGTSVVGPHRDEVDFLINQNPAKSYGSQGQQRTLVLALKLAELQLLEQIIGEPPLLLLDDVLAELDIERQNQLLDAIEDRFQTLITTTHLSSFESRWLQSSQVFSVKKGHIFY
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SHESM
Sequence: MYAVFQSGGKQHRVAPGHTVRLEKLEVATGSTVEFDQVLLIADGEKVHVGAPLVAGGKVVAEVVSHGRGEKVTIVKFRRRKHHDKKMGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YAP1_CHICK
Sequence: MDPGQPQPQQPPQAAQPPAPQQAAPQPPGAGSGAPGGAAQPPGAGPPPAGHQIVHVRGDSETDLEALFNAVMNPKGANVPHTLPMRLRKLPDSFFKPPEPKAHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPSGVVTGPGAPSSQHLRQSSFEIPDDVPLPPGWEMAKTPSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNLMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSSSNQQQQMRLQQLQMEKERLRLKHQELLRQELALRSQLPTMEQDGGSQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDSISQSNIPSHQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKPDKESFLTWL
What is the function of this protein?
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity).  Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (By similarity).
What are the official names of this protein?
Transcriptional coactivator YAP1, Yes-associated protein 1, 65 kDa Yes-associated protein, YAP65, Protein yorkie homolog.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.