PharMolix/UniProtQA huggingface dataset:
Protein: ENO_DROME
Sequence: MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_STAA2
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKGAYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEKVIEHAARAIEKFVETSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_MYCTU
Sequence: MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COTH7_RHIO9
Sequence: MKSLSFISLACLTAVHAASVTFKVIAPTAESSVQVNINGQLTQLKAQDEDIPYYTGSAELNDGQSYKYVVDGAAETFERILNGTSTKNEFFNRPITYATNIPELPNILSEGSWTRGETTDPLWDSNYVPSIFVTGKSDEMEDLITNVTKKTYQAKITFIGPENITTIENCTFGLHKPGRKHNDAKQTWVWTLPEGQYVAKRSWFKIRHMEEDPTQLREKLYADIARKMGTYANEANMVRFFINKEGMGTFNMLDDVIMYSYINAMFYNGNPPQQLGALYDGASGAAFNASGDMDSFIPNVESPLDQDALMPFSKAFAAVDFSNDDQVKAISQYFDYDQFLRFMVMEFLTADWDGYWQEQTNDGAYIDVSDNNKVYYLAQDFDATFGVNLDQERDFVNTPYTDFPTKFPGGILINKLLENPTTKATFETYLKTTVQEIFNNATLGAYVTARHNFLAPDLKWDRSIKQRSPGNIFGWTYEQTYQNLFEGVTAPGKEQGGAEWGLLEWVAAKEKAVRSSLKLSETATTSTSATIAAPATSESASQDNTSDDTDSASTSSSTLNQAAADTSSASKSAPTFYCLQLVLYLSLSFKNLYKYI
What is the function of this protein?
Promotes invasion of host epithelial cells by adhering to receptors on the host cell surface to facilitate endocytosis of the pathogen into host cells (PubMed:32487760).  Probably binds integrin ITGA3:ITGB1 via ITGB1, on the cell surface of host alveolar epithelial cells (PubMed:32487760).
What are the official names of this protein?
Invasin CotH7, Spore coat protein homolog 7.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: BIP1_TOBAC
Sequence: KVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKERIDARNSLETYVYNMKNQINDKDKLADKLESDEKEKIETATKEALEWLDDNQSAEKEDYEEKLKEVEAICNPIITAVYQRSGGAPGGGSSEEEEDGHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein 1, BiP 1, 78 kDa glucose-regulated protein homolog 1, GRP-78-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RLMD_NEIL0
Sequence: METEVNVAEISALDYEGRGVTKVGGKTVFIKGALPSERVGFRIVRQKKQFDEAEAVAIFKVSDERTVPQCRYFERCGGCSLQHISPAAQVAFKQRMMEEQLERIGKVKPKQILLPIYGHVWHYRDRARFSVSLDKLCRLKLGFQAKKTNDVVDISSCMLLPKPVSDKLSAIRGLLQDLAEEGSVARFAEFYRGSEITVLNIAFKSKLRQNEENRIRQWFDSELSDGWQVWLQIEGGVSQPFYPKTDKTLKYTLPEFGIEMPFRPGDFTQINTDTNRLMVSRVVKMLDIRRGERIADLFCGLGNFSLPMAKSGADVVGIEGAENLVRRARQNARLNGCDRQTDFIAANLFDCTEKTVASWERFDKMLIDPPRSGAYEVVKSLHTPYLPQKIVYVSCNPSTLARDAGVLVEKGYMLSQAGIMNMFAQTSHTESVAVFDLLPQTGKNFLKIKGKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: Y1144_CLOD6
Sequence: MIYLKKSFNSTIKVKEMAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANYIINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIMNPWDIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRSASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMII
What are the official names of this protein?
UPF0758 protein CD630_11440.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: HNRPL_MOUSE
Sequence: MSRRLLPRAEKRRRRLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGGGNEGGRAPKRLKTENAGDQHGGGGGGGSGAAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPDYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
What is the function of this protein?
Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion (PubMed:22523384).  Exhibits a binding preference for CA-rich elements.  Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts.  Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.  As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPK and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein L, hnRNP L.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules.
Protein: SDHA_YEAST
Sequence: MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADGKYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAALGNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIYQRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTHNGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGFPLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVVSRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIPIIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSLLDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNMKQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLTCASQTAVSAANRKESRGAHAREDYPNRDDEHWMKHTLSWQKDVAAPVTLKYRRVIDHTLDEKECPSVPPTVRAY
What is the function of this protein?
Catalytic subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).  SDH1 and SDH2 form the catalytic dimer.  Electrons flow from succinate to the FAD bound to SDH1, and sequentially through the iron-sulfur clusters bound to SDH2 and enter the membrane dimer formed by SDH3 and SDH4.
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, FP.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RUVB_ECOSM
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NDB4S_CHATC
Sequence: MNSKYLFVFLILIVTFTDLCQGFLVGILPRMRGFITPFLKKVRGRRELGSQYDYLQDFRKRELDLDDLLSKFPDY
What are the official names of this protein?
Peptide Ctri10033.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: UXAC_PHOLL
Sequence: MKNFMCDDFLLNNETARQLYHEHAADMPIYDYHCHLNPREIAENRRFDNLGQIWLEGDHYKWRAMRCAGIDESLITGKQTRDYEKYQAWAETVPLTLGNPLYHWTHLELRRPFGISGILFGPQTADEIWHQCNEKLAAPAFSARGIMQQMNVRMVGTTDDPVDSLQYHRQIATDESFDIEVLPSWRPDRVFKIELAGFIDYIKQLEAVADVSIVAFADVLNALERRLEHFAAHGCRAADHGIENLRYAPIPDETVLNGILQKRLAGGILSELEIAQYTTAILVWLGRQYAARGWVMQMHIGAIRNNNSRMFRLLGADSGFDSIGDNNIAWPLSRLLDSMDVTDELPKTILYCLNPRDNEVIATMASNFQGGGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQLGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNVLGQWAEKGEIPNHKAMLGQIVEDICFNNARRYFALPGENL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RF1_ANAD2
Sequence: MLSPDVLKKLEAIEQRFEELTQLLSDPAVAGNGDRFRKVAKERASIEQTVTALRAYRKLLEDVEGNEALLADKDPELRELAKEELAQLRPQVDPAEEQLKLYLVPKDPNDEKDVIVEIRAGAGGDEAGLFAAEVMRMYVRYAERRGWRVELMDTSGGALGGVKEATLTVSGDAVYSSLKYESGVHRVQRVPATEAQGRIHTSTVTVAVMPEAEEIDVQVNPADVEMDVFRSTGSGGQSVNTTDSAVRLTHKPTGIVVKCQQEKSQLKNRTMAMKMLRAKLFEIEQERQRSARDATRKSQVGTGDRSEKIRTYNFPQDRLTDHRVNYTRHNLPAVMDGDVQDVIDACRTFYAAQALREASRGEAGAAERRA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOC_BACTN
Sequence: MNKTIIAERFSKAISTYPREANVQRQIANKMIRLLQKHIPSPCPKVIEFGCGTGIYSRMLLRTLRPEELLLNDLCPEMRYCCEDLLREKQVSFLSGDAETISFPDKSTLITSCSALQWFDSPEEFFKRCNTLLHSQGYFAFSTFGKKNMKEIRELTGKGLPYRSREELEAALSLHFDILYSEEELIPLSFEDPMKVLYHLKQTGVNGLSAQSSLYPKHEKQTWTRRDLQHFCERYTQEFTQGTSVSLTYHPIYIIAKKKKV
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MCA4_TRYBB
Sequence: MGGCVSTALKVGAETVAEGHIDLISFAINYFKNAVPYIVKYLGRQQRPKEVDMEATLTEAKESKGFQPWKISCQPKGAVRGLFIGVNYGNTEAQLSGCCHDIMMMIGALQKRNFPLTEVVILADEEDVPGRTGEPTRANILRYLAWLAQDAQPNDVLFFHYSGHGTRANARDDDCEEYDQCIVPMDYVENGCIVDNEIHEILVSQLPKGVRLTAVFDCSHSGSMLDLPYAYVCDSSKDGSGSCGMKRVREDNDVQADVLMISACADDEAALGVDNTQDFYESGKDSGGAATFCLTAMMMREEPLTFLDLLVHTREMLKSRGFTQVPHLSASKPINLMQRFSLEGLFPQERTLL
What is the function of this protein?
Inactive metacaspase which plays a role in parasite bloodstream form growth and in parasite virulence within the mammalian host.
What are the official names of this protein?
Inactive metacaspase-4, TbMCA4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Lipid-anchor; Cytoplasmic side. Secreted. Note=Secreted by the parasite bloodstream form (PubMed:21949125). Membrane localization is required for MCA4 processing but is dispensable for MCA4 secretion, and parasite growth and virulence in the mammalian host (PubMed:21949125).
Protein: SPIR_DROPS
Sequence: MTEHHMDVQADATQSASESKAMAAPKGKFSEAEEGFLSTSPDSANGDAQQAHTHTHIISHTHSKGAAKTQTQTQNGNGTLGMGLGAPMLPGGSRQLLRQAFYQCSCPEQCVTLNNILDSFKAPLSEDQAWALIYQFGSLYYKVAAQAHKSGGDYEADLPSRFELHFHRDGNVHFSGAERLPELVESQEQEASQQEQQQKQPQMDDSATSSVDSNAALDRAFDNNNHEHHHHHHHQHHHPVDSNAALDRAHHTPLVVSHRKIISEMAEIVYTALDYNLPEDEECQMSQELENLFNFMTADETDEDCIDEGIDEGDKRWDDEAEEERNDTKELEHIIETCRNHLQKPALADNHYKAVCRALATETIELRVFLQQVLNNGAEKLIKAAESSPTTQKELAKLGFNDWARFWVQVIDELRRGVRLKKSNFERTPIEYELTPYEILMGDIRAKKYQLRKVMVNGDIPPRVKKDAHAMILEFIRSRPPLKKASERQLGPPRMCTPTPREQLMESIRQGKELKQITPPEAPPLRQRMLPSANSTLSRSRQRLIKVDFSQLQDDELFFDDSSMSSSHSTAATHQHHQQHQPHHAHLAELHRCSQPKMPPYPFGGYMVPSQARQECQATATQLRPRRTMDTSAPRQTLPQPQAQARPPPPAEPSFTEDEYHRFFDNALESYDLATQCESRRASLRRHTIVGCQSNLEETHSMPPTRPESRQSDDAGSQSQSGASSEAPGIRKSPLMEGDHSQTTDGPPRLDEAHSTSSLGPWNKSFMDKQTWMERGDDRLSVTLAEIVHIRSVMTKAELEGLPMDVRVKEDVEKRRVCFLCLRTRFSFFGPWGIQCKLCQRTVCAKCYTKMRIPSEHFRNVPLVLISPSLLSSPASSSTPSPSHHAHQAHSSSTGNIMDDQFPKSLIERLLRSESDRKTRSTVGSAPSSPKHQRSNMSTPGISVGPGAGASTSAAPGHAVEALHDQAAMSASYSSAMRPSGVMQHHQKHHYNNAMSRSMEGPRSLPVHSPAYRPLSNSSTLERKSRFSRGFALFSSGSHLAQTQDQKENLRGEQVPVCNDCQGLVNEITSSVKQKRSSARNRTIQNLTLDLTPVWK
What is the function of this protein?
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament.  Promotes dissociation of capu from the barbed end of actin filaments.  Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport.  Required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal anterior corner.  Links Rho family signaling and Jnk function to the actin cytoskeleton (By similarity).
What are the official names of this protein?
Protein spire.
What is the protein family that this protein belongs to?
Belongs to the spire family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Punctate spots in perinuclear region and cytoplasm.
Protein: LPXK_RHIL3
Sequence: MISEAPPFWWRKADWRAWLLLPLSFLYGRIAGHRMAHARRASVPVPVICVGNFTVGGAGKTPTAVTIARAAKAKGLKPGFLSRGYGGSLDVTTVVDPDHHRAIAVGDEPLLLAQEALTVISRRRVEGAARLVAEGADLIIMDDGFQSARLAIDYALLVIDSTRGLGNGHIVPGGPVRAPIGQQLRSATALLKVGGGNAADRIVRMAARAAKPYFTASLRVRGDNTLAGTKVLAFAGIADPAKFFRTVESRGAEIVVAKSFGDHEHLTEEEIDDILTTAEREGLLIVTTSKDFVRLSGHHGKAARLVEKSRVIEVDMVFEDHLAPSLIIDRAIVACRERRLREMKAGVKAIPAKAEPL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: HIS8_BRUAB
Sequence: MQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGEKLELYPDGQALALRQAIAETQGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFAVYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVFIANPANPTGTYLPFEEVRRLHAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMTRTFSKIHGLPGLRIGWIYAPLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRVTPSVTNFLLIHFPDDAAHSADKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVVAALTEFLK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ITA8_HUMAN
Sequence: MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA
What is the function of this protein?
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures.  It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN.  NPNT is probably its functional ligand in kidney genesis.  Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
What are the official names of this protein?
Integrin alpha-8.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cell membrane.
Protein: PDXH_JANMA
Sequence: MSIADIRTDYTQAKLSELDTDPDPVAQFAKWFGEALRAEVPEPNAMSVSTVAANGRPSSRILLIKDFDQRGFTWFTNYESRKGQELAQNPHAALLFHWIPLEREVRIEGRVERVSSAESEQYFQSRPVKSRLSALASSQSHPVADRTALEAQYAKVEAQYGEHPPRPEHWGGYRLKPDYIEFWQGRASRLHDRIVYSLDKEGKWQRHRLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CCR5_MICHU
Sequence: MDYQVSSPIYDIDYGPSEPCRKIDVKQMGAHLLPPLYSMVFLFGFVGNMLVVLILINCKRLKSMTDIYLLNLAISDLIFLFTVPFWAHYAAGQWDFGNTMCQFLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGYHYTCSPHFPFSQYQFWKNFETLKMVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTYQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCVNPIIYAFVGEKFRNYLKVFFQKHIAKCFCECCSIFQKEAPERANSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCPB_STRZJ
Sequence: MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQKYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQPITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHLEELPVIDELEIQAQESQLFGERIEEDENQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: HSLV_PSEE4
Sequence: MTTIVSVRRNGKVVMGGDGQVSLGNTVMKGNAKKVRRLYNGQVIAGFAGATADAFTLFERFEAQLQKHSGHLVRAAVELAKEWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGLIAMGSGGGYAQAAARALLNKTDLSAREITEAALNIAGDICVFTNHNLTIEEQDLAE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M5H43_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGALKELASTYLQRKRTAEDHEEMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVISKIGGVLGGLLKNLG
What is the function of this protein?
Maximin-H4 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 5/H4 type 3.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31_PERFR
Sequence: MADKGSKPRKEEVVSREYTINLHKRLHGCTFKKKAPKAIKEIRKFAQKAMGTTDVRVDVKLNKHIWSRGIRSVPRRIRVRIARKRNDDEDAKEELYSLVTVAEIPEGGLKGLGTQVIDEEE
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.