PharMolix/UniProtQA huggingface dataset:
Protein: STHR_PHANO
Sequence: MSTISFFATSKRTSCDRCRKQKLRCPPDKDDMGTCGRCLRAGVACATSYTKPRGRSQKHGISTDGTSHVSGLDMQEPALPTPESVLSAGLTSSVQVAEDGSQLWSPLEEYNHLPSLSNFESGALSQSQDEDFAGLWWSPLHEDLDLDVHMDPSGACQNGYSAEISSFSRTDCSRQSNDCSPETLQHVECDMRLSQLNLELCRQSKAYHHWPNTTSDGSVRRPHFAIASALRDLLQNTEAFIHILHCLRNGTELNLDGRYQEPISTHDTGVSPPSLAFPSILNLTSCFFRIVDLFNVLLSSLALELATHSPLQRRSSSSSVTSALQILPDLKLAGLAVQEVSLQTKILVLTITHHFETMERLLGLPADLRVSECKDDNGYGLLGASWTSVLSSGRREKFELGWRRTGNWVTSIESLKANMGTLTKGSC
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of the phytotoxin stemphyloxin II.
What are the official names of this protein?
Stemphyloxin II biosynthesis cluster transcription factor sthR, Stemphyloxin II biosynthesis cluster regulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMCL_CONRE
Sequence: RVLFRSGDQPADQPAERMQDISPEQNPLFHPDKRRCCPMPGCFAGPFCPCCPP
What are the official names of this protein?
Reg12l, Reg3.4, Rg3.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_MYCMM
Sequence: MSSDSRPPQPDTSTQSNSESESPAISSPTPQDHAPMTNRDWWPNQIDVSMLHPHPSQASPLGADFDYPKEFAKLDVDALKADVMSVMTTSQDWWPADYGHYGGLFIRMSWHAAGTYRIQDGRGGGGQGMQRFAPLNSWPDNVSLDKARRLLWPVKQKYGSKISWADLIIFAGNCALDSMGFKTFGFGFGREDVWQPEEVMWGEEDVWLGTDKRYSGKRDLAQPYGATTMGLIYVNPEGPEGKPDPVAAAHDIRETFARMAMNDEETAALIVGGHSFGKTHGAGDADLVGPEPEAAPIEQQGFGWKSSFGSGKGKDAITSGLEVVWTPTPTQWGNGFLELLYGYEWELTKSPAGAWQFTAKDGAGAGTIPDPFGGPGRAPTMLVTDISMREDPIYRRITQRWLEHPEELTEAFAKAWYKLLHRDMGPVSRYLGPWVAEPQLWQDPVPDVDHELVDAKDVAALKSKVLASGLTVAQLVKTAWSAASSFRRTDKRGGANGGRLRLEPQKSWESNEPADLDQVLSVLEGIQQDFNSSAAGGKKISLADLIVLAGSAAVEKAAKDGGHEVSVPFAPGRTDASQENTDVESFAVLEPRADGFRNYVRVGEKAPLEHLLIERAYRLGVTAPEMTVLVGGLRALGANHGGSKHGVFTDNPGVLSNDFFVNLLDMGTEWKASEAAENVYEGCDRSSGQLKWTATANDLVFGSNSVLRALAEVYAQSDAKQKFAEDFAAAWAKVMNNDRFDLE
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: SPED_SALG2
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDQTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTETERQEITAALWKEMREIYYGRNISAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: FKBP9_MOUSE
Sequence: MALGARGWRRRSLLLLLLWVTGQAAPVLGLAVSSELQIQQSFVPDECPRTVHSGDFVRYHYVGTFLDGQKFDSSYDRDSTFNVFVGKGQLIAGMDQALVGMCVNERRLVTIPPNLAYGSEGVSGVIPPNSVLHFDVLLVDIWNSEDQVHIQTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITVPPFLAYGEEGDGKDIPGQASLVFDVALLDLHNPKDTISIENKVVPENCERRSQSGDFLRYHYNGTLLDGTLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEKGRGSIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVSGLPEGYMFIWNGEVSPNLFEEIDRDGNGEVLLEEFSEYIHAQVATGKGKLAPGFNAEMIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL
What is the function of this protein?
PPIases accelerate the folding of proteins during protein synthesis.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP9, PPIase FKBP9, 63 kDa FK506-binding protein, 63 kDa FKBP, FKBP-63, FK506-binding protein 9, FKBP-9, FKBP65RS, Rotamase.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TYRP2_BOVIN
Sequence: MSPLGWGLLLGCLGCALPSGARAQFPRVCMTVGSLQAKECCPPLGADPANVCGSREGRGQCAEVQTDTRPWSGPYVLRNQDDRERWPRKFFDRTCRCTGNFAGYNCGNCRFGWTGPKCDQKKPLVVRRDVHSLTPQEREQFLDALDLAKYTLHPDYVITTQHWLGLLGPNGTRPQIANCSIYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERDLQRLTGNESFALPYWNFATGRNECDVCTDQLLGAARQDDPTLISQNSRFSSWEIVCDSLNDYNRRVTLCNGTYEGLLKRNQMGRNSEKLPTLKDIQNCLSLKKFDSPPFFQNSTLSFRNALEGFGKADGTLDSQVMNFHNLVHSFLNGTSALPHSAANDPVFVVLHSFTDAIFDEWMKRFNPPVDAWPRELAPIGHNRMYNMVPFFPPVTNEELFLTADQLGYSYAIDLPVEETPDWTTVLSVVTGMLVVLVVLFALLLFLQYRRLRKGYTPLVETQLSNKRYTEEA
What is the function of this protein?
Plays a role in melanin biosynthesis.  Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
What are the official names of this protein?
L-dopachrome tautomerase, DCT, DT, L-dopachrome Delta-isomerase, Tyrosinase-related protein 2, TRP-2, TRP2.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: Y2548_BRUO2
Sequence: MSRQPILDIKGLRTVFRTRAREIVAVNDVDIVVNPGETVALVGESGSGKSVTSLSIMRLLARKVGFIDAGSIILRGKSGQTVDLAAIDEEAMRRIRGNDIGMVFQEPMTSLNPVYTIGDQIGEPLRVHRGTSRREALEAVVELLDRVGIPDARRRAGQYPHELSGGMRQRATIAMALICNPTLLIADEPTTALDVTIQAQILDLMQKLQSESGMGMLFVTHNLGVVAEIAQRVVVMYAGRIVESGPVKEVFRNPRHPYTMGLLRSMPRLGDATEMKRRGEKLNTIPGMVPGLANLPSGCAFAPRCSFAVEACHAAVPPLASVNEHHGSRCIRWQEIAA
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative peptide import ATP-binding protein BOV_A0348.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBP2_BOVIN
Sequence: KQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVSDEESKDSRAGATTAADVSGAPNTETTGPTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKSPGKLNQSGASVGTDEDSDVTQEEERDGQHFEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDAGQWKERGIGDIKILQNYENKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTERVWVWTACDFADGERKIEHLAVRFKLQDVADSFKKIFDEAKVAQEKDFLITPHVARSATPRESPCGKMAVAVLEETTRERTDLSQGDDAADTTSEVGGVSGTPEPTTKAVVSPPKFVFGSESVKSIFSSEKSKPFAFGNSSATGSLFGFSFNTPLKNNSSEASSAAQSGSERKVEPGGRQESQNSDLKSASDGKVKNTSPAFLKEQFSTSHTFKTPEKVEERKKPEDLPSDDDVLIVYELTPTPEQRALASRLQLPPTFFCYKNRPDYISEEEEDDEDFDTAVKKLNGKLYLDDSETCRLSEENVTDNEKECVIVWEKKPTVEELAKADTLKLPPTFFCGICSDTDEDNGNAEDFQSELQKVQEAQKSQDENIASSADGMCTDDTKVTVPFLCKSEEPEFTTKSVSSPSVSSGTVDKPVDLSTRKENDADSTSQVESKTVTFGFGSGPGLSFADLASSNSGDFAFGSKDKNFQWANTGAAVFGAQSTSKVGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDREASQWKDRGVGDIKILWHTVKNYFRILMRRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDYADGEAKVEQLAVRFKTKEMADCFKKKFEECQQNLLKPQKGQDSLTAEFSKETNPVVFFDICADDEPLGRITMELFSNIVPKTAENFRALCTGEKGFGFKSSIFHRVIPDFVCQGGDITKHDGTGGRSIYGDKFEDENFDVKHTGPGLLSMANRGQDTNNSQFFITLKKAERLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVSRRIIITECGQI
What is the function of this protein?
E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I.  Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates.  Binds single-stranded RNA (in vitro).  May bind DNA.  Component of the nuclear export pathway.  Specific docking site for the nuclear export factor exportin-1.  Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB.  Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle.  Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
What are the official names of this protein?
E3 SUMO-protein ligase RanBP2, 358 kDa nucleoporin, Nuclear pore complex protein Nup358, Nucleoporin Nup358, Ran-binding protein 2, RanBP2, p270.
What is the protein family that this protein belongs to?
Belongs to the RanBP2 E3 ligase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Nucleus envelope. Note=Detected in diffuse and discrete intranuclear foci. Cytoplasmic filaments.
Protein: SYV_METBF
Sequence: MTESEIPKEYNASEVEEKWMDKWDLSMYHFNWGEDPRPQYIIDTPPPYPTGNFHIGNALNWCYIDFVARYKRMRGYNVMFPQGWDCHGLPTEVKVEEIHGITKNQVPRAEFRKMCRELTAGNIDKMRKTMLRLGFSVDWSNEFITMDPSYFVKTQKSFVRMYNKDYIYHEEHPVNWCPRCETAIAFAEVEYETRQTKLNFVHFDKVDIATTRPELMAACVAVAVNPEDKRYSQYVGQEITVPLFGQKVTLIADEDVEPEFGTGAVMICTFGDKQDVRWWVKYELPLIKAIDKQGKMTKAAGKYEGLSIAECREAVVADLKAAGFLYDQKPLEQNVGLCWRCDTPIEILSEPQWFVKIDNDAILKAADEIKWYPEYMKVRLQNWTGTMEWDWCISRQRIFATPIPIWHCKKCGEVMVAEESWLPIDPNEAAPKKACACGSTEFEPETDVLDTWMDSSITALHVTGWESEHDLRLPAQIRPQGHDIIRTWAFYTILRSLALEGKRPWDSIVINGMVLGPDGHKMSKSLGNVISPEEVTTKYSADAFRQWGAVGGSTGSDVMFRWKDVVSASRFLQKMWSIYRFSMSHLKGFGQEDAEKFQKDSLHIIDRWLLSKLNRLVDTATKELDDYQFDSTFKAIRGFAWEVLADNYLELVKGRLYGDDPEGKRAAQYVLYRTTKTLSLLLAPFIPFFAEELYSRLSDESVHTQAWPAVDESLINEEAEAAGELIKEITGEVRRYKSELGMALNAPLKKLEIYNADIDTGDIAGAANSKVELMEGAPSFEYVPVEVKPNMGILGPRFRKDAGAVVKALKAESPAAIEAQAASGKITVNVDGKPIELEPEAVEIRKEVISGGREVDVLEVRGAVVVIVR
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CUTAK
Sequence: MATTIKPLEDRVLVQPLEAEQTTASGLVIPDTAKEKPQEGKVISAGPGRVDDKGTRVPMDVKEGDVVIFSKYGGTEVKYDGQEYLLLNARDILAVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_CERS1
Sequence: MSRYDPAATESRWQAAWDAAGVFTARHDPARPKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARQKAAAGFSVLHPMGWDAFGMPAENAAMERGGHPKDWTYGNIADMRAQMKPLGLSIDWSREFATCDPEYYGQQQAMFIDMMEAGLVYRKNAVVNWDPVDMTVLANEQVIDGKGWRSGAPVVRRELTQWFFRISDYAGELLEALDTLKDWPEKVRLMQANWIGQSRGLQFAFSMAGAPEGFDRLEVYTTRPDTLMGASFAAISPDHPLARHLERHDAEVAEFVAECRRVGTSEEALEKAEKKGFDTGLRVRHPFDTAWELPVYIANFILMDYGTGAIFGCPAHDQRDFEFATKYGLPIRPVFLPEDTEETALAEAFVPMKSERVHYIRGFAGAEVQTGEEGVAAAIDFCESQGVGRGVTNYRLRDWGISRQRYWGCPIPVIHCETCGVVPEAKENLPVRLPDDVSFDVPGNPLDRHPTWRDCTCPKCGAKARRETDTMDTFVDSSWYYARFTAPRAATPTDAEEADYWMNVDQYIGGIEHAILHLLYSRFFARAMQKTGHLPAKAIEPFNALFTQGMVTHEIYLTRDAAGRPVYHLPEDVTDGRLADGTPVEIIPSAKMSKSKKNVVDPMNIIRQFGADTARWFVMSDSPPERDVEWTASGAEAASKHLHRVWRLADEISRADGEANAEDGALDKATARAIAEVTQGVEGFAFNKAIAKLYEFTNTLSRSGAGAEAKKRAMRTMAQLMSPMVPHLAEEVWAMLGGEGLVAQAAWPKADPALLIDDTVTLPIQVNGKRRGEITVPKEMAASEVEKLVLADEAVQRALGGAAPKKLIVVPGRIVNVVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_CAMLR
Sequence: MKKADILVLDFGSQYTQLIARRLREQGVYAEILPFNVSLDEIKAKEPKGIILSGGPASVYANDAYFCDKGVFDLNIPVLGICYGMQLMAHHFGANVAPAGHKEYGKATIDIQNDSDLFKNLPKKQTVWMSHSDKVENLPQGFEVLATSENSPFCVFGDEKRKFFALQFHPEVQHSEFGKSILKNFAKYACNCDSVWNMGSFAKTQAQKIKEEVGNDKVLCAVSGGVDSSVVAALLASAIKDQVVVVFVDNGLLRSGEKEQVEYMFKHTLGIDLISIDAREIFLSRLAGVRDPEQKRKIIGNTFIEVFEEEAKKHKDVKYLAQGTLYTDIIESSVVGASKTIKSHHNVGGLPEKMNLKLIEPLKEIFKDEVRALGMELGLSKDVVYRHPFPGPGLAIRIMGEVNEPSLELLRKADVILIEELKSSGWYDKTWQAFCVLLNVQSVGVMGDNRTYDNAVCVRVVNASDGMTATFSHLPYELLENISRRIINEVNGINRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MUTL_BAUCH
Sequence: MQIHRLSPQLINQIAAGEVVERPASVVKELIENSLDAGATRIDIEVELGGAKVIRIRDNGYGISKKDIVLAVARHTTSKISSIEDLECIKSMGFRGEALASISSVAHLNLTSRTAKQNEAWQVYTERYTEKVMLLPIAHPVGTTVEVLDLFYNTPARRKFMRAEQTEFKHIEEVIRRMALARFDVTFILQHNNKIVQHYRAVKEPSQYWRRLSRLCGNTFVNNALKISWQNIDFSIQGWVEDPSCIKLPEMQYSYVNQRIIRNKLINHAIRHAYQDQLKGPHQPSFVIFIVINPQQLDINVHPAKKEIKFYEARKVHHFIYQALMTVLQQRVKLSSDTCYSTTQKPIGKIIPSHALNQLNEGKNNILVSYSAAAKNADELLSNQIIQDPDEAKMQDIPAKCQATKNSCSTSLSNDFYSFGKMLTFCSPCYALLESAQGLSLLSLQFAERYITERQLTPENNSDTILAQPLLIPLRIILSNGEASALHQHRLLLQRMGILLQPNENETILNAVPLPLLRKKNLSNLILDLLRYLNNETSVTYHKIASWLACSLNSQITTWNYSRAIPLIAEVERLCPHWIKNPPNALIVKLDLKMAIKALNNS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: BTNL9_MOUSE
Sequence: MADFSVFLGFLKQIPRCLSIFFTYLLFLQLWEVNSDKVWVLGPEESILARVGEAVEFPCRLSSYQDAEHMEIRWFRAQVSNVVYLYQEPQGRSSLQMAQFRNRTLFEAYDIAEGSVNLHILKVLPSDEGRYGCRFLSDNFSGEATWELEVAGSGSDPHISLQGFSGEGIQLQCSSSGWYPKPKVQWRGHQGQCLSPESEAITQNAQGLFSLETSVIVRGGAHSNVSCIIQNPLLPQKKEFVIQIADVFLPRMSPWKKAFVGTLVVLPLSLIVLTMLALRYFYKLRSFQEKQVKQGEEVREKLQTELDWRRSEGQAEWRAAQQYAADVTLDPATAHPSLEVSNNGKTVSSRLGVPSIAAGDPQRFSEQTCVLSRERFSSGRHYWEVHVGRRSRWFLGACLESVERSGPARLSPAAGYWVMGLWNRCEYFVLDPHRVALALRVPPRRIGVLLDYEAGKLSFFNVSDGSHIFSFTDTFSGALRAYLRPRAHDGSEHPDPMTICSLPVRGPQVLEENDNDNWLQPYEPLDPAWAVNEAVS
What are the official names of this protein?
Butyrophilin-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SECA_YERPG
Sequence: MLIKLLTKVFGSRNDRTLRRMQKVVDVINRMEPDIEKLTDTELRAKTDEFRERLAKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSIGINLPNMTAPAKRAAYAADITYGTNNEFGFDYLRDNMAFSPEERVQRQLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYIRVNKLIPKLIRQEKEDSDSFQGEGHFSVDEKSRQVHLTERGLILIEQMLVEAGIMDEGESLYSPANIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVPTNRPMIRKDLADLVYMTEQEKIGAIIEDIRERTANGQPVLVGTISIEKSEVVSAELTKAGIEHKVLNAKFHAMEAEIVSQAGQPGAVTIATNMAGRGTDIVLGGSWQSEIAALEDPTEEQIAAIKAAWQIRHDAVLASGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKTTIDSYIPTQSLEEMWDIEGLEQRLKNDFDLDMPIAKWLEDEPQLHEETLRERILQQAIETYQRKEEVVGIEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISVLSKVQVRMPEEVEALEVQRREEAERLARQQQLSHQTDNSALMSEEEVKVANSLERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GPMI_CHLAD
Sequence: MTRPRPVVLIIMDGWGVAPPGPGNAADLADTPHVDEWMATCPFTTLGASGLDVGLPEGQIGNSEVGHLNIGAGFIVYQELTRISKAIADGDFFTNPAFLQAIEHVKQHNSALHLMGLFGPGGVHAHEDHLHALLELAHRQQVRRVYLHLFLDGRDVLPRSALGFLDTLEGVIARLGVGVIATVSGRYYAMDRDKRWERTGRAYAALVDGIGERATSARAAIEAAYANDISDEFVLPTVIVDAHGTPVATVRDGDAVIFTNFRPDRGRQLTRAFVDPDLNERIRQHYERQKAEGQPLPPQIWQRDRQLHDLCFVTMTQYEEGLPVLVAFPPRYVTTPLAAVISQAGMRQFHIAETEKYPHVTFFLNGGREEPFPGEDRRLIPSPKVATYDLKPEMSAPEVTEALLQAITSDQYDFIVVNYANPDMVGHTGSIPAVIKACEAVDAGLARVVPAILERGGVALVIADHGNAEQMIDPETGGPHTAHTTNPAPCFLIGGPGYGKDTIRLRSGGRLADVAPTLLELLELTPPADMTGQSLIVRNL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: KGUA_BIFLO
Sequence: MTENTHAGRLIVLTGPTAVGKGTVEAKLRADHPEVWVSVSATTRAPRPGEVDGVNYWFLTEDEFLAREAAGEFLETAVVHGMAHYGTLLKPVEEHLAAGVPTILEIDLQGARRVKQRAAELDLEVVYVFIAPPSFEELERRLIGRGTETAEQQARRLETAKVELAAESEFDVTIVNETVDQAAADLWSVIAKEYGL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6P_BPF1
Sequence: MPVLLGIPLLLRFLGFLLVTLFGYLLTFLKKGFGKIAIAISLFLALIIGLNSILVGYLSDISAQLPSDFVQGVQLILPSNALPCFYVILSVKAAIFIFDVKQKIVSYLDWDK
What is the function of this protein?
Plays essential roles both in the entry of the viral genome into the bacterial host and in budding process.  The formation of the G3P-G6P complex termed adsorption complex is essential for correct termination of filamentous phage assembly (By similarity).
What are the official names of this protein?
Head virion protein G6P, Coat protein D, G6P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G6P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Multi-pass membrane protein. Note=Prior to assembly, G6P is found associated with the bacterial host inner membrane. There are about five copies of G6P in the mature virion. They are located together with G3P at the head side of the filamentous virion (By similarity).
Protein: COX1_VANPO
Sequence: MLQRWLYSTNAKDIAVLYFIFSVFCGMAGTGMSMIIRLELAGPGNQYLGGNHQLFNTLVTGHAILMVFFLVMPALIGGFGNYLLPLMIGASDMSYPRLNNISFWLLPPALVCLVTSTLVESGAGTGWTVYAPLSGIQSHSGPSVDLAIFALHMTSISSLLGAINFIVTTLNMRTNGMSMHKMPLFVWAIFITAFLLLLSLPVLSAGVTLLLMDRNFNTSFYEVAGGGDPVLYQHLFWFFGHPEVYIMIVPAFGVISHIVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYVVGLDCDTRAYFTSATMIIAIPTGIKIFSWLATIYGGSIRLAVPMMYAIAFLFLFTLGGFTGVALANASLDVAFHDTYYVVAHFHYVLSMGAVFSMFAGYYYWSPHILGLNYNEKLAQIQFWLIFVGVNVIFLPMHFLGINGMPRRIPDYPDAFAGWNYVSSIGSFIAMISLILFIYILFDQLYNGLENKINNKSVTFMKAPDFVESNNKFNLNTIKTSSIEFLLNSPPAVHSFNTPAVTN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ASAP2_HUMAN
Sequence: MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
What is the function of this protein?
Activates the small GTPases ARF1, ARF5 and ARF6.  Regulates the formation of post-Golgi vesicles and modulates constitutive secretion.  Modulates phagocytosis mediated by Fc gamma receptor and ARF6.  Modulates PXN recruitment to focal contacts and cell migration.
What are the official names of this protein?
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2, Development and differentiation-enhancing factor 2, Paxillin-associated protein with ARF GAP activity 3, PAG3, Pyk2 C-terminus-associated protein, PAP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups.
Protein: BSUHB_ARCFU
Sequence: MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK
What is the function of this protein?
Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate.  Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate.  May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, FBPase/IMPase, Inositol-1-phosphatase, I-1-Pase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.