PharMolix/UniProtQA huggingface dataset:
Protein: PSBO_EUGGR
Sequence: MSRVNLAAPANHVVPRAAQEEVQGEYQTASNNWAVAAMASAGAAVGAAVLAMRRRATNTYEAIREDPEAVLAGAGRAMGAALIGAAVAGSANAASLTYDELQSLSYLEVKSSGIAGTCPVLADGVSSKLSLKAGKYEINNWCLEPSSFQVKLPPTEKQQVTEFERTKLMTRLTYTLDAISADLNVGGDGSWTIQEKDGLDYAATTVQLAGGERVPFLFTIKNLLAKGDAGQFLGQFDVPSYRGATFLDPKGRGGASGYDTAVALPASGDDEEYAKENSKSTAASVGTIAFKVAKVNAETGEIAGVFESIQPSDTDLGAKVPKDIKTSGVWYAQISPSK
What is the function of this protein?
Stabilizes the manganese cluster which is the primary site of water splitting.
What are the official names of this protein?
Oxygen-evolving enhancer protein 1, chloroplastic, OEE1.
What is the protein family that this protein belongs to?
Belongs to the PsbO family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: SECA_DEIGD
Sequence: MFRVLNKVFDTNQRDVQRIVKTVVQPVNALEEETMKIENLAEAFMRLRQRVQEGGESLDDVLVPAFALIREAGRRAIGKRHYDVQLIGGTALHQGRIAEMRTGEGKTLVATLALALNALEGKGAHLVTVNDYLARVGAEEMGLLYRTLGLSVGLITRDMQPHQRQAAYACDITYVTNSELGFDYLRDNMAQSREQLVLRADNPLHYAIVDEVDSILIDEARTPLIISGAAEKATDLYYVYAKLVKRLQRGEPAEPGKRTEPTGDYTIDEKGKQVHLTEQGIAKIERLLSLGDLYSPENMDKAHMITQAIRARELYHREKDYIVNAEGEVVIIDEFTGRSMPGRRYGEGLHQAIEAKEGVKIENENQTLATITYQNFFRLYDKFAGMTGTAKTEEKEFLDIYGSDVLVIPTNKPVIRQDADDLVYRTRMGKYQAVVEEVKQMHATGRPILIGTASIDTSEQLSALLKQAGIRHSVLNAKYEAQEASIIAQAGRSGTVTIATNMAGRGTDIMLGGNAEFILGEAIEQNFGISRFTPEAEAFIKAIGREDPEAVTLGLRIPGMTEQFIRQAQQLQKDIIADRERVRELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYVSFEDDLMRLFASDRVVAMMDRLGMDDTQPIEAKMVTGAIERAQARVEDRNFGIRKQLLEFDNVMSKQRDIIYAQRREVLLGTDEDVEESTEGMIADFTEMQLAFYAPIDQPAESWDLETLRTNMLEAVPQLEHYDFEALRHMAPEAAHAHLLEAVADAFDARKAELGPTMLNSLARYVLLQVVDQHWKEHLHGMDVLRQGIGLRGYGQRDPFTEYKFEATNMFNDMIDNLKADVTKFIFRMQFGQAS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: MURC_SYNS3
Sequence: MADSIQPEKHIHFIGMGGIGMSALALILAERGHSVSGSDRKLTPAMQALETKALAIFESQVSKNFAHLQSRGIEEPLVVVSTAIPSTNPELIEAQRLDLTIWHRSDLLAWLIEQQPSIAVAGSHGKTTTSTVLTTLLATVGEDPTAVIGGVVPCYGSNGHKGNGRLLVAEADESDGSLVKFKASLGIITNLELDHTDHYRNLDDLIETMKTFGRGCKRLLINHDDPILKEHFQADACWSVHHVETADYAALPVQLDGDRTIADYFEQGQKVGQITLPLPGLHNLSNVVAALAACRMEGVPLEALLLAVTELRSPGRRFDFRGEWQDRQVVDDYAHHPSEVQATLTMAQLMVQSGRSPLPRTPQRLLAVFQPHRYSRTQEFLNAFAQALVSADALVLAPIYGAGEQPIEGINSELLARSIRLIDPNQPVFVASTMEELAGLVKQHSQPDDLILAMGAGDVNSLWERLSQEGIGGEASCSPAIAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BURA4
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAIADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GLK_RALSO
Sequence: MGSMDDVTAYPRLVGDVGGTNARFALEMAPMRLAHIGVLAGDDYPSLEAAMRAYLAALPPEIAAAGVRHAAIGIANPVLGDQIRMTNRDWAFSTEAMRQSLGFDTFVVLNDFAALAHALPYLGADELEQVGGSTCVADAPRALLGPGTGLGVASLLPTQAGRFIAVAGEGGHVAFAPMNDEEVVIWRFARERFGHVSAERLISGMGLELIYEALGACFDLWQQGPAVRRAADITAIALGEMEDTAGDHARCRYAVDTFCAMLGTVAANLAVTLGARGGVYIGGGIVPRLGAAFANSPFRRRFEDKGRFSGYVAAMPVYVIHAPYPGLIGLCAAMDHAVASGH
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSA2_COCIM
Sequence: MPQNEYIERWQKQHGKRLDHEERTRKRIARESHKQSQDAQTLRGLRAKLYHKKRHAEKIQMRKRIKAQEERDVKSAAPNEPSTTPLPQYLLDRSQATNAKALSSAIKEKRAEKAAKFSVPLPKVKGISEEEMFKVVKTGKKTSKKSWKRMITKPTFVGNDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKWAQITNNCENDGCVNAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CLCKB_HUMAN
Sequence: MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLVQALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTNPPAPK
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.  May be important in urinary concentrating mechanisms.
What are the official names of this protein?
Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. CLCNKB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BAB1_BABBO
Sequence: MEAQSATETQKNLKTLMELIKTKRPFKSSDFDTLNLDYLSGQSNEELFKLLIDAINGMKENVAKVNEYLTEEGDHSLSGDELLKFVYKELVYDDESEFDKEKLQKLYKTFSEDSNAFATLQSYIQYLQPEENSQRWIQVHEPVKHRRRLNHNPALQEISMDSRVQPSQLDLHSPFRDCLSLLSATSFLSAF
What are the official names of this protein?
Gene BABR protein 1.
Protein: HEM3_PARDP
Sequence: MTQMPDPQNPIRIGTRGSALALAQAHETRDRLMAAHGLAADAFRIVVIKTTGDRVLDRPLKEIGGKGLFTREIEDALLAHEIDIAVHSMKDMPTIQPEGLVIDCYLPREDVRDAFVSAQFAAISELPQGAVVGSSSLRRRAQLAARRPDLKLVEFRGNVQTRLKKLEDGVAVATFLAMAGLTRLGMLHVARGAVEPDEMLPAVAQGCIGVERRADDARTASLLAAISDRDSALRVTAERAFLARLDGSCQTPIAGLAELQGDRLRLRGEILRPDGSEVIAAERVGPAADGAAMGTDLAEELRGRAPADFFDWS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PUR5_HAEIE
Sequence: MSNTQLSYKDAGVDIHAGNELVERIKGDVKRTNRSEVMGGLGGFGALCALPTKYKEPILVSGTDGVGTKLRLAIDLKKHDTIGQDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDVAASVIKGIAYGCEMSGCALVGGETAEMPGMYHEGDYDLAGFCVGVVEKSEIIDGTAVKTGDTLIALGSSGAHSNGYSLIRKVLEVSGANPADLLEGKPLSEHFLAPTKIYVKSILQLIKQTEVHAIAHLTGGGFWENIPRVLPDNTKAVIDESSWQWPAIFNWLQEKGNISRYEMYRTFNCGVGMVIALPEKEVETALALLEQSGEKAWVIGKIEHLGEGEAQVEIQ
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBI1_MOUSE
Sequence: MAQTVQNVTLSLTLPITCHICLGKVRQPVVCTNNHVFCSICIDLWLKNNSQCPACRVPITPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHREYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLALMQGSQNEDKHPLADNPSKMDPDSVVEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLLRENLRLKAEVDNRSPQKFGRFTVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAHLKHSEEAKEDVDALCQRAPSADSKGPNGSDELGPPKNQSDSARKQAGSASASHLASPSSSRLADSGSVRQESTSRTEPNCPQNKDRYPKPTEPRLGARETPMDTYLEREWGSKPSDCAPYKEDELYGIPASCTPLSLSCLQLNTPENRENPVIKAGSSKKHANHLRKLVFDDFCDSPNACNNNSSEDDRRENEKKSDCFASSKTGFWDCCSTSYAQSLEFDGSEGNAIANSVGEIPSKLSEKSGSCLSKRLSCIRSLEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNNGFKSVEVEGPSKSPQGREFLEEPDKLQEGSKLNLSKPALTADGLESGGEWKPSSFFLLSPADHEMSEDFSLHSTSHSGTSEVKPPNCLFQTEFSQGALLSSSQGLFEDQRFGSSLFKISSEMQSLHSPLQSPWSAAFVPEKRSKNGNQSTKRKIQSSLANASPSKATKS
What is the function of this protein?
E3 ubiquitin ligase essential for DNA replication origin activation during S phase.  Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase.
What are the official names of this protein?
ORC ubiquitin ligase 1, OBI1, RING finger protein 219.
What are the subcellular locations of this protein?
Chromosome. Note=Association to chromatin is cell cycle-regulated, absent from mitotic chromosomes, is associated with chromatin from G1 and partially released from chromatin from mid S-phase.
Protein: RAS1_DROPS
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLTTWNVKNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKLNKPNRRFKCKIL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: FACR1_PONAB
Sequence: MVSIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIESTNIIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCLGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY
What is the function of this protein?
Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols.  It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols.  In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
What are the official names of this protein?
Fatty acyl-CoA reductase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: GOG8H_HUMAN
Sequence: MAEETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSVPEKATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKGKLNTDLYHMKRSLRYFEEKSKDLAVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDPESREAMSSFMDHLEEKADLSELVKKKELCFIHHWRDRCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPGAPAPQELGAADKHGDLCEVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPLLCWAWLPRRRR
What are the official names of this protein?
Golgin subfamily A member 8H.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
Protein: VPS29_CHICK
Sequence: MAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKDTYDYLKTLAGDVHVVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYHALENNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity).  Acts also as component of the retriever complex.  The retriever complex is an heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrins.  In the endosomes, retriever complex drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 29, Vesicle protein sorting 29.
What is the protein family that this protein belongs to?
Belongs to the VPS29 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: PYRI_HALMA
Sequence: MSDNDQQLRVSKIQNGTVIDHIAGGQALNVLAILGIDGTSGDSVSVAMNMPSDRLGHKDVVKVEGRELSQNEVDVLSLIAPAATINIIRDYEVVEKGRVERPSVVEGVLECPNHNCITTENEPVDSRFAVGDDGVRCEYCDTIIRDDLPAHILAE
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RS11_STRU0
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RUVB_SHEWM
Sequence: MIEADRLIHAEPQGIEERDEQIDRAMRPKMLDEYTGQDDSRAQLKIFIQAAQNRDEALDHMLIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPGDVLFIDEIHRLSSVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVTRSANVLELPIDEAGAIELARRSRGTPRIANRLLRRVRDFAEVKHDGEITKQVAELALDMLDIDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIATDRAYRHFDIIQPEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RF1_ZYMMO
Sequence: MIAISPDRLAAIIARREELQAEMARPDLDSNRLVALSREYSEVEPVALAAENVGRLREEGETLEAMTKDDDPELQAMAVEELEANKTALAEAERALALSLLPRDAADERSAILEIRAGTGGDEAALFGGDLLRMYSRYAEEHGWRVEMISASAAELGGYKEVVISITGAGVFARLKFESGVHRVQRVPVTESGGRIHTSAATVAVLPEAEEVDVDIDERDLRIDIFRSSGPGGQSVNTTDSAVRITHIPSGIVVSQQDEKSQHKNKAKAMKVLRARLYERERERLHSERAGQRKSMVGSGDRSERIRTYNFPQGRVTDHRINLTLHRLPEILAGPGLDEVISALIAEDEAERLASLDD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_BACCR
Sequence: MEKTFLMVKPDGVQRAFIGEIVARFEKKGFQLVGAKLMQVTPEIAGQHYAEHKEKPFFGELVDFITSGPVFAMVWQGEGVVDTARNMMGKTRPHEAAPGTIRGDFGVTVAKNIIHGSDSLESAEREIAIFFKEEELVDYSKLMNEWIY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_TREDE
Sequence: MDTSQLKERVAYHAIDTLFSEGKIFDGMKIGLGTGSTAMPAVHRLAQLLSSGKLKKIYAVPTSFQTSIECEKLGIPIYSLSSQQIGGSLDLAIDGADEIDPDKNLIKGGGAALLKEKIIAYNSKEFVVIADERKKVKSMGKGFALPIEIIPEARLSITKALEAQGIEVFLREGVKKMGPVVTDNGNFIIDVKWPKAADVDPKALEESLNKITGVVENGFFTKNTPRVFIVHQDGNIEDL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RS6_THEP1
Sequence: MAYVKERIYESMFIIAPNVPEEERENLVERVKKIIEERVKGKIEKVERMGMRKFAYEIKKFSEGDYTVIYFRCDGQNLQELENFYRVTPEIIRWQTFRRFDLEKKERKAQREKAAAEAVETGEGGSEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: AMIE_HELPS
Sequence: MRHGDISSSPDTVGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEYSTHGIMYDRQEMFDTAASVPGEETAILAEACKKNKVWGVFSLTGEKHEQAKKNPYNTLILVNDKGEIVQKYRKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAMRGAELIVRCQGYMYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDGHTLGECGEEENGLQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAECPFEFYKTWVNDPKKAQENVEKFTRPSVGVAACPVGDLPTK
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: LPXD1_SULDN
Sequence: MNLKDIAKIINSDFSGEYFEITKMNTLRDATKSEISFVANAKYIKEIQNSNAGAIIVSKDTKEFVPSGCVALVVENPYWEMATLSKYFAPSIEDETLPEPKIGEGTTISPRAEIARGAIIGKGCTIMAHVYIGTNAVIGDNTIIYPSVTVYRDCRVGSECIIHANTTIGSDGFGFATNKQGEHRKIYQNGNVEIEDNVEIGSSTTIDRAVFGTTLIKYGVRIDNLVQVGHNCVIGEHSVLVAQAGISGSTTMGRNVVMGGQSATAGHLSIAPFTTMAARSGVTKSIDKSGLTFAGFPLLEHRLWLKLQAKIARLIKQN
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PNCB_BRUSU
Sequence: MAKTDLARRVYNHTWKLDPIIRSLLDTDFYKLLMLQMIWGLYPRVDATFSLINRTSSVRLADEIDEGELRAQLDHARTLRFSKKEMIWLAGNTFYGRKQIFQPEFLAWLHDFQLPEYELRRKDGQYELHFHGPWTHTTMWEIPALAIINELRSRAAMKNLGPFSLDVLYARAKAKMWSKVERLRQLPDLKISDFGTRRRHSFLWQRWCVEALKEGIGSAFTGTSNVLLAMDTDLEALGTNAHELPMVLAALAKTDDELRSAPYRVLQDWNRYYGGNLLIVLPDAFGTAAFLRNAPDWVADWTGFRPDSAPPIEGGERIIEWWKSKGKDPREKLLIFSDALDVDTIEETYRHFEGRVRMGFGWGTNLTNDFAGCAPQSIDGLKAISLVCKVTDANGHPAVKLSDNPQKATGDPKEVARYLRFFGNEERVEQLVRV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: RL35_SYMTH
Sequence: MPKMKSHRGAAKRFKLTGSGLVKHYPSNKHHKNTHKKENRIRALKRNLVLSKSFQKNIREILPH
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RRG9_YEAST
Sequence: MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
Protein: UBC22_ARATH
Sequence: MASNENLPPNVIKQLAKELKSLDESPPDGIKVVVNDEDFSQICADIEGPVGTPYENGLFRMKLALSHDFPHSPPKGYFMTKIFHPNVASNGEICVNTLKKDWNPSLGLRHVLSVVRCLLIEPFPESALNEQAGKMLLENYDEYARHARLYTGIHAKPKPKFKTGAISESTTALNVGQTNNETPGAATAIPSSMTDIKRVTTSAQDQQHVANVVVAASASVVTTTQKREAGLAKVQADKKKVDARKKSLKRL
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 22, E2 ubiquitin-conjugating enzyme 22, Ubiquitin carrier protein 22.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.