PharMolix/UniProtQA huggingface dataset:
Protein: URE1_RHOOB
Sequence: MTDLSRARYAELFGPTTGDRIRLADTDLLIEITEDRGGGPGLAGDEAVFGGGKVLRESMGQGRATRAEGAPDTVITGVVVVDHWGIIKADVGIRGGRIVALGKAGNPDTMSGVHPDLVVGPSTEIIAGNGKILTAGGIDCHVHFICPQIMDEALGGGITTMIGGGTGPAEGSKATTVTPGSWHTARMLEALDGWPMNIALLGKGNTVSSESMWEQLRGGVSGFKLHEDWGSTPAAIDACLTVADAAGVQVALHSDTLNEAGFVEDTLAAIAGRAIHAYHTEGAGGGHAPDIITVAAHANVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLSPKIPEDLAFAESRIRPSTIAAEDLLHDLGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKRRRGFLAGDNGADNQRVQRYVAKYTICPAVAHGLEDEIGSVEVGKLADLVLWDPAFFGVRPHAVIKGGMIAWAAMGDANASIPTPQPVLPRPMFGAAPKAAAATSVHFVAPHALEDGLADRLDLSRRLVPVANVRSRGKADMPRNDAQPRIEVDPDTFTVRIDGDVWEEQPAAELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEGF9_MOUSE
Sequence: MNGGAERAMRSLPSLGGLALLCCAAAAAASTASAGNVTGGGGAEGQVVPSPSPGLRDQASSPFPKTAAPTAQAPRTGPPRTTVRKTGATTPSAGSPEIIPPLRTSAQPAATPFPALDLSPATPSEDGHTPTTESPPSRPAPTTLASTVGQPPTTSVVTTAQASSTPGTPTAESPDRSSNSSGVPPTAPVTEAPTSPPPEHMCNCSEVGSLDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPHGAVSILCNSSGNCQCKVGVTGSMCDKCQDGHYGFGKTGCLPCQCNNRSDSCDVHTGACLNCQENSKGEHCEECKEGFYPSPDAAKQCHRCPCSAVTSTGNCTIESGELEPTCDQCKDGYTGQNCNKCENGYYNSDSICTQCECHGHVDPIKTPKICKPESGECINCLHNTTGFWCEKCLEGYVRDLQRNCIKQEVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFAVSSSENSTSALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA
What are the official names of this protein?
Multiple epidermal growth factor-like domains protein 9, Multiple EGF-like domains protein 9, Epidermal growth factor-like protein 5, EGF-like protein 5.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HPT_ATEGE
Sequence: MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIANGYVEHLVRYQCKKYYRLRTEGDGVYTLNNEKQWTNKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSRHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKNQLVEIEKVVLYPNYSQVDIGLIKLKDKVPVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQYQCVKHYEGSTVPEKKTPKSPVGQQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYAAGILSFDKSCGVAEYGVYVKATSIQDWVQKTIAEN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BL1S1_BOVIN
Sequence: MLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS
What is the function of this protein?
May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation.  May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 1, BLOC-1 subunit 1.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Mitochondrion matrix. Cytoplasm, cytosol. Lysosome membrane.
Protein: RL27_PAEAT
Sequence: MAHKKGASSTRNGRDSNAQYLGVKRFGGQVVSAGEIIVRQRGTHFHPGAGVGRGGDDTLFALQAGAVEFGTRRGRRVVNIVAAAAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YZ05_AQUAE
Sequence: MKVYKRLYELLGRGYKPLKSARLIKRGKDYYIGITLQKAVKEKKIKKPRYVINVDLNVQRNLACIGIFEVDWEKRESKLYGIKFVNGKLLRLVYKRDYLFEEIRKKQRQTGRSPQVGDNSRLWKKVNNLNRDIALKVAKEISDIAREFSEKGEVIVVFEKLKGLRGRKGRSKKLNRKINFWMRRKIQERVKELGLEEGFGLDFVYPHYTSKKCSKCGYEGERFSPSGSKALFLCKKCGYVVNADVNAVFNQHFLYLSHLLNGGGKARPVVRVGTSLKSPSREGHNLSGVPKATTTFFYISSLLSTF
What are the official names of this protein?
TnpB-like protein aq_aa05.
What is the protein family that this protein belongs to?
Belongs to the transposase 35 family.
Protein: GUAAB_METBF
Sequence: MVKPEKFIPKAVEKISKEIKDGRAIIALSGGVDSSVCAELAHRAIGGRLQPIYIDTGLMRKGETERIKHIFSHMNLDIVYAKDRFLAALKGITDPEEKRKAIGETFIRVFEEEARKLEADYLIQGTIYPDRIESEGGIKSHHNVGGLPSVMDFKKIVEPIEDLYKDEVREVAWALKLPDEICERMPFPGPGLAVRILGEVTEEKLEVAREANSIVEEELLDRFCPWQTFAAVIGKGTGVKGDIRAYGWIIAVRAVGSRDGMTAEALELPWDVLKKLESRITSEIPKVARVVYDITPKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: INVE_ARATH
Sequence: MAASETVLRVPLGSVSQSCYLASFFVNSTPNLSFKPVSRNRKTVRCTNSHEVSSVPKHSFHSSNSVLKGKKFVSTICKCQKHDVEESIRSTLLPSDGLSSELKSDLDEMPLPVNGSVSSNGNAQSVGTKSIEDEAWDLLRQSVVFYCGSPIGTIAANDPNSTSVLNYDQVFIRDFIPSGIAFLLKGEYDIVRNFILYTLQLQSWEKTMDCHSPGQGLMPCSFKVKTVPLDGDDSMTEEVLDPDFGEAAIGRVAPVDSGLWWIILLRAYGKCTGDLSVQERVDVQTGIKMILKLCLADGFDMFPTLLVTDGSCMIDRRMGIHGHPLEIQALFYSALVCAREMLTPEDGSADLIRALNNRLVALNFHIREYYWLDLKKINEIYRYQTEEYSYDAVNKFNIYPDQIPSWLVDFMPNRGGYLIGNLQPAHMDFRFFTLGNLWSIVSSLASNDQSHAILDFIEAKWAELVADMPLKICYPAMEGEEWRIITGSDPKNTPWSYHNGGAWPTLLWQLTVASIKMGRPEIAEKAVELAERRISLDKWPEYYDTKRARFIGKQARLYQTWSIAGYLVAKLLLANPAAAKFLTSEEDSDLRNAFSCMLSANPRRTRGPKKAQQPFIV
What is the function of this protein?
Chloroplastic invertase that cleaves sucrose into glucose and fructose and is associated with the development of the photosynthetic apparatus and the assimilation of nitrogen in seedlings to control the sucrose to hexose ratio (PubMed:20304912).  Participates in the carbon flux between the cytosol and plastids in leaves (PubMed:18034262).
What are the official names of this protein?
Alkaline/neutral invertase E, chloroplastic, A/N-INVE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 100 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GGT_BACNA
Sequence: MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHALASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGTRSMKLLITLTIKLAEKGFPIDSVLADAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQMLKILDDFNLSQYDVRSWEKYQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVEGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMGLKAAVEEPRIYTTSMSSYRYEDGVPKDVLSKLNGMGHRFGTSPVDIGNVQSISIDHENGTFKGVVISGSNDAAIGINLKRK
What is the function of this protein?
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds.  The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases.  Uses glutamine as a gamma-glutamyl donor and acceptor for gamma-polyglutamic acid synthesis.  Dipeptides are better gamma-glutamyl acceptors than free amino acids (PubMed:1371053).
What are the official names of this protein?
Glutathione hydrolase proenzyme, Gamma-glutamyltranspeptidase proenzyme, Gamma-GTP.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NINAC_DROME
Sequence: MMYLPYAQLPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQHYDEEHQVSIEEEYRTLRDYCDHPNLPEFYGVYKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDIDFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASRSCQDQDLIMDRVSEKHSQFVKKHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQGYFRDPQQLRRNQMQMNMNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQQRSSYPPSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFEEAGSYVEEEIAPGITLSGYAVDI
What is the function of this protein?
Required for photoreceptor cell function.  The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities (PubMed:2449973).  Essential for the expression and stability of the rtp protein in the photoreceptors (PubMed:20107052).  The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina (PubMed:20739554).
What are the official names of this protein?
Neither inactivation nor afterpotential protein C.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Membrane. Note=Localizes in the cytoplasm or punctate structures within the nuclei in the absence of rtp. Co- localizes with rtp in the rhabdomere membrane.
Protein: RK33_STAPU
Sequence: MGKNKDVRITITLECTNCPQNKLKRYPGISRYTTQKNRRNTPNRLELKKFCPHCSLHTLHKEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSRA_IDILO
Sequence: MLILTRRVGETLMIGDDVSVTVLGVKGNQVRIGVNAPKDVSVHREEIYMRIQSEKDDEQDKE
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_HERAR
Sequence: MEYISPFDRFIRHFDSALRVMSGVSAASRPSPASGVADGVLDDAERRHSAGLMRVNHVGEVCAQALYQAQAQFAHSDAIKQQFELAGREEEDHLAWTAQRLRELGSHPSLLNPLWYAGAYALGTVAAKLGDARSLGFVVETERQVEAHLNEHMNRLPPQDAKSLAVVAQMSADEVAHGSAAQALGAQAVPPLAQKGMQAISKIMTTTAYYI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARX1_DEBHA
Sequence: MQLAVHQDDADILLKERNQLNESILDKYRVAGQIAQTGLKYVISLINDSYHLGKTETPYTCQELCVMGDSMVTRLLAKVYNNDIREKGISNPVSIELNEIVGNFAPEIDDASKFTFNAGDIVTITLGVHIDGYAANVSHTVVIYPTGVTIDNELKPPGPLLGSKADSICAAHIATETVVALLGMALTPEKLPTQLDPNNTKLVTGKQIRNIVNSIAESFNCTVVPGSKVRRIRRFLAGQAEGVVAEKDFKGVVWSESDQEELLLNKYNKNDDQQLVLHNKQGSEFTNNSSAIPTDEFVVAADEVYNVDIKMCSTSDFKELGLVTLEEIDEFTGLNNKTNEFKTKSTIYIRDYAVNYQLRLKNSRSLLGKIDKEFTVFPFKLSHTSPSFPATNSQDLATLKKELIANKLGLSELANRHLINAKPIQVTKFIPFETILKTSNPTGKHGIDSNKPALPGMEIPLPHLGISSLKLKALLKNSSSIANARESTTVILNSFNNANEVIRLTGGNNSAPSWVHSDYSLNPQCKESVDHLLQLTKDKRFGIKVKECQPMKLTADAPESMQMD
What is the function of this protein?
Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Probable metalloprotease ARX1, Associated with ribosomal export complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECR_FUSNN
Sequence: MPTKSLERLILEFNKLPGVGQKSATRYAFHILNQSEEDVKNFAEALLAVKENVKKCHVCGNYCESDTCNICSDNARDHRIICVVEESKDIMILEKTTKFRGVYHVLNGRLDPLNGITPNELNIKSLLERIAKDDIEEIILATNPNIEGETTAMYLAKLMKNFGIKITKLASGIPMGGNLEFSDTATISRALDDRIEI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MSRQ_SHIF8
Sequence: MRLTAKQVIWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFACATLHLTSYALLELGVNNLPLLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSR1_CAEBR
Sequence: MSTTGHRAGVFKKPAKPHKSWKGKRTKGEITTENRGREGVKQLTRSAHSTHRAVSKDARRNQLKMARDRKMADAMERRRTSNAPCLVTILSLGVGARPSEFLKKLATCDETIVQTHSPSTIDFAIPRFKSRISFLTPDKENVDSVLDAIRASDVLCFLWPLSAELSEWDEQLLTICKAAGLPTIVSVVPGLGGIQNHKKKEDVRKGIEFTISKWSMSNAGVMPADSVTDNLQLLRTLNETKKKPLTLQARHSYMLVENLEATESPEDSSKITLKAQGYLRGPEWNANNLIHLPGFGDFQISKIETAADPHPLKTSPPKGAEVIAKADEKRQSLETEITLDAMDGEQTWPTQEELEEADKEMRRVPKGTSSYQAAWILDDSEDDEDEEDEDEDMDDEEEDKDLEEDDEEEDTPMDLKSEAGETTASEMMFHDEIDEDINLAEVEKYRKERENAQWPDEVDTPIDQPARIRFQKYRGLKSFRTSTWDAKENLPVDYARIFQFANYKNTKKNVMSKIGGNDVDAGDAVIDKKFNGVFASVYIENVPVSVMEAYKETKNLVLFQLLPHEQKMSILNMVLKKHPSCTVPIGSEDQKFIFYVGFRQFEAHAVLSSNTPGDKFKLERFMPTEKTFVATVYAPITFNPATVLCFRQDDKGRQELVATGSVLDTNPDRIVLKRTVLSGHPYKINRRAVVVRYMFFNREDIDWFKPVELYTPSGRRGHIKEAVGTHGHMKCRFDQQLNAQDSVMLNLYKRVFPVWDYSLFNRNLNPSRFVERSRVESISLVQEDAMEE
What is the function of this protein?
Required during maturation of the 40S ribosomal subunit in the nucleolus.
What are the official names of this protein?
Pre-rRNA-processing protein TSR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ILVC1_BACCR
Sequence: MAKVYYEKDVTVNVLKEKKVAIIGYGSQGHAHAQNLRDNGFDVVVGLRKGKSWDKANEDGFSVYTVAEAAEKADVVMILLPDELQPEVYEAEIAPNLQAGNSLVFAHGFNVHFDQVKPPANVDVFLVAPKGPGHLVRRTFAEGGAVPALFAVYQDATGVATEKALSYADGIGATRAGVLETTFKEETETDLFGEQAVLCGGVTALVKAGFETLVDAGYQPELAYFECLHELKLIVDLMYEGGLENMRYSVSDTAQWGDFVSGPRVVTEDTKKAMGAVLAEIQDGTFARGWIAEHKAGRPNFHATNEKENKHEIEVVGRKLREMMPFVQPRVKVGVK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)) 1, KARI 1, Acetohydroxy-acid isomeroreductase 1, AHIR 1, Alpha-keto-beta-hydroxylacyl reductoisomerase 1, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RS8_STRP2
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREGFVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAILSTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CH601_NOCFA
Sequence: MAKQIEFDEKARRALERGVDKLADAVKVTLGPRGRHVVLAKAFGGPTVTNDGVTIARDIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVRGGLKNVAAGANPIAVGSGIAKAADAVSEALLAAATPVSGEQAIAQVATVSSRDEEIGEMVGKALTTVGKDGVVTVEESSTLQTELVVTEGVQFDKGYLSPYFITDTDTQEAVLEDAFVLLHREKISSLPDLLPLLEKIAEAGKPVLIVAEDVEGEALSTLVVNSIRKTLKAVAVKAPFFGDRRKAFLDDLAVVTAGTVVNPDLGITLREAGIDVLGKARRVVVTKDETTIIDGAGTAEDIAARAAQLRREIEATDSDWDREKLEERLAKLAGGVAVIKVGAATETALKERKYRVEDAVSAAKAAVDEGIVPGGGTALVQAATKLVELRDSLSGDEAVGVEVVRKALEAPLFWIASNAGLDGAVVVSKVAEGKEGFNAATLSYGDLLTDGVVDPVKVTRSAVVNAASVARMVLTTESAVVDKPAEEAEDHSHHGHAH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANX10_MOUSE
Sequence: MFCGEYVQGTIFPAPNFNPMMDAQMLGGALQGFDCNKDMLIDILTQRSNAQRQMIAGTYQSMYGRDLISVLKEQLSSHFKEVMVGLMYPPPSYDAHELWHAMKGPGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQANREEGYSDPAMAAQDAMVLWEACQQKTGEHKTMMQMILCNKSYPQLWLVFQEFQNISGQDLVDAINDCYDGYFQELLVAIVRCIQDKPSYFAYKLYRAIHDFGFHNKTVIRILIARSEIDLMTIRKRYKERFGKSLFHDIKNFASGHYEKALLAICAGDVEDY
What are the official names of this protein?
Annexin A10, Annexin-10.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: RS11_ALIFM
Sequence: MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCGEMAKEYGVKNLEVMVKGPGPGRESTIRALNAAGYRITNIVDATPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CITD_STRPG
Sequence: MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNHIRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_CUPTR
Sequence: MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKIVAAKMVHLSRGEAEQFYAVHKERPFFKDLVDFMVSGPVMIQALEGENAIAKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEVAFFFPGMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_AZOVD
Sequence: MAKQKKHPQGNIAQNKKALHDYFIEQKFEAGLALSGWEVKSLRAGKAQLVDSYVLLKDGEAWLMGSHITPLKTASTHVIADPTRTRKLLLHKRELGRLFGSVQQKGYACVALSLYWKKHLIKCEIALAKGKKEYDKRDTEKARDSDREIQRAIRSKGKED
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RFP2_SCHPO
Sequence: MNLHGLELPGRDQRLSPEVIDLTEDIEDDGADVSEVTLLDLTRIPEFQPRRRIRTSRNHLDANLSNVPTINSIPSPVTRPPVAVGGGIFYGARRTRNRSQTQRRTLLENGFRNSRKKAQDSSNSIAERVSPPPGFCYDVHPHNNIACAKCGNELVSDEKKSIFAAKCGHLFCSTCAKELRKKTVPCPVQHCRKRITKKFIFPLYL
What is the function of this protein?
Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains.  Involved in maintaining genome stability where it acts in the cellular response to DNA damage.
What are the official names of this protein?
E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2, RING finger protein 2, RING-type E3 ubiquitin transferase rfp2.
What are the subcellular locations of this protein?
Nucleus.