PharMolix/UniProtQA huggingface dataset:
Protein: Y2648_BURVG
Sequence: MPSFDVVSEANMIEVKNAIEQSNKEISTRFDFKGSDARVEQKERELTLFADDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKIGGDKVKQIVTVKKGVTGDLAKKIVRLVKDSKIKVQASIQGDAVRVAGTKRDDLQSVIAMLRKDVTDTPLDFNNFRD
What are the official names of this protein?
UPF0234 protein Bcep1808_2648.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: Y603_VIBVY
Sequence: MGLFSRRAIGNQYESLAKEYLQRQGLRFIEANFTTKVGEIDLIFKEAQTIVFVEVKYRKNSCYGDAAEMVNPAKANKLIKTAYLWLNKHGYNACNTAMRFDVVAIHSNGHDINWIANAITQG
What are the official names of this protein?
UPF0102 protein VV0603.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: AMSC_ERWAM
Sequence: MAIYWIVSYSILVFCFFELAMINQASEAKTKILINYFFLIGVFALILFAGIRGPDSGMDDSQYVGFFHDFSRQTGMTGYQAVANIYRYENFFMVLAWVASCFTHESYFFLLFISFIAVSTNAWVYKKYSPLILCSLCLYSAHLFINKDMNQIRFGLCSAFAIAFICSLVARNYLLALLFIVLSTQSHSTGYTIVMIIPFFFIRERKYLPLVLVIASIPLGIIGGKKLFLDSLGIVPVLGERAASYSGTNFDTTSPVFGLANLKNIAFIGAFTLYYFRKGIMKEDRFVYILLIAYSIGAAVRITFSDFSIFGGRVGNLFLHTEPLLFAFLMLRIRNLLLNFFMLFSITTYYLAYNTILSAQSIMGYSVAPLFRIFS
What is the function of this protein?
Involved in the biosynthesis of amylovoran which functions as a virulence factor.
What are the official names of this protein?
Amylovoran biosynthesis protein AmsC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NOB1_METJA
Sequence: MLSLPPPEFYKLWIINKSPYQLFNIYRSGIMKVKVLDASAIIHGYNPIIEEGEHYTTPEVLEEIESKKIIVEQALDFGKLKIMSPNREYIKKVEEVVKKTGDNLSQQDIGVLALALNLNAILYTDDYGIQNVAKKLNIEVRGIAFEPTNKDFIWRKICEGCKKLYPVDYEEDICEICGSPLKRKMVKSRLKKKRKKK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity).
What are the official names of this protein?
Endoribonuclease Nob1, RNase Nob1, Endonuclease VapC5, Putative toxin VapC5.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: Y1207_MYCPA
Sequence: MSLPFLGPMSLSGFEHSWFFLFLLVVAGLAALYILMQLARQRRMLRFANMELLESVAPKRPSTWRHLPAILLVASLVLFTIAMAGPTNDVRIPRNRAVVMLVIDVSQSMRATDVAPNRMAAAQEAAKQFADELTPGINLGLIAYAGTATVLVSPTTNREATKNALDKLQFADRTATGEGIFTALQAIATVGAVIGGGDKPPPARIVLFSDGKETMPTNPDNPKGAFTAARTAKDQGVPISTISFGTPYGFVEINDQRQPVPVDDETLKKVAQLSGGNAYNAASLQELKSVYATLQQQIGYETIKGDASVGWVRLGALVLALAALTALLINRRLPT
What are the official names of this protein?
UPF0353 protein MAP_1207.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAK_CUPMC
Sequence: MGKIIGIDLGTTNSCVSILEGNTPKVIENSEGARTTPSIIAYMEDGEILVGAPAKRQAVTNPRNTLYAVKRLIGRKFEEKEVQKDIGLMPYAIVKADNGDAWVGVRDQKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGMDKNEKGDRKIAVYDLGGGTFDISIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKITRAKLEALVEELITRTIEPCRTAIKDAGVKVSDIDDVILVGGMTRMPKVQEQVREFFGKEARKDVNPDEAVAVGAAIQGSVLSGDRTDVLLLDVTPLSLGIETLGGVMTKMINKNTTIPTKHAQVFSTADDNQPAVTIKVYQGEREMATGNKMLGEFNLEGIAPAPRGTPQIEVSFDIDANGILHVGAKDKATGKENRITIKANSGLSEDEIQRMVKDAEANAEEDKRARELADARNQADALIHSTRKALGEYGEKLEAGEKEKIEAAIKDLEDAARGGDKAEIDAKVNALSEASQKLGEKVYADMQAQAGEGAAAGAGAAGGAQQQAQPQDDNVVDAEFKEVNDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GAPN_STREI
Sequence: MTKQYKNYVNGEWKLSKEEIKIYAPATGEELGSVPAMSQEEVDYVYASAKAAQKAWRALSYVERAEYLHKAADILMRDAEKIGAVLSKEIAKGYKSAVGEVIRTAEIINYAAEEGVRLEGEVLEGGSFDPASKKKIAIVRREPVGLVLAISPFNYPINLAGSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSVIGDYIVEHEAVNYINFTGSTPVGEHIGHLAGMRPIMLELGGKDSAIILEDADLDLAAKNIVAGAYGYSGQRCTAVKRVLVMDSIADKLVEKVSALVNNLTVGMPEDNADITPLIDTKAADYVEGLIKDAQEKGAKEVISFKREGNLISPVLFDNVTTDMRLAWEEPFGPVLPFIRVNSVEEAIEISNKSEYGLQASVFTNNFPLAFKIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGVQGVKYSIEAMTTVKSTVFDIAK
What is the function of this protein?
Catalyzes the irreversible NADP-dependent oxidation of glyceraldehyde-3-phosphate to 3-phosphoglycerate.  Is not able to use NAD instead of NADP.  May play an important role in NADPH production in S. equinus.
What are the official names of this protein?
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)], GAPN, Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase, Triosephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ENO1_STRCO
Sequence: MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPSRYLGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGAEVYHTLKKVLKNKGLATGLGDEGGFAPNLGSNREALDLILEAIKEAGYTPGEQIALALDVAASEFYKDGSYAFEGKNRSAAEMTEYYAELVEAYPLVSIEDPLFEDDWDGWNTITAKLGDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIGSLTETLDAVELAQRNGFKCMMSHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDDAAVYAGRSAFPRFKG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CMOA_ESCF3
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHQAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CISY_RICS2
Sequence: MTNENNNDSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPRQLYTGYVHREYKGIRER
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: NRAM1_BISBI
Sequence: MSGDTGPPKQGGTRYGSISSPPSPEPQQAPPGGTYLSEKIPIPDTESGTFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITIVDAFFFLFLDNYGLRKLEAFFGFLITIMALTFGYEYVVAQPAQGALLQGLFLPSCPGCGQPELLQAVGIIGAIIMPHNIYLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQAAFNICANSSLQDYAPIFPRNNLTVAVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLLAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPALMREFANGLVSKVITSSIMVLVCAVNLYFVISYVPSLPHPAYFSLVALLAAAYLGLTTYLVWTCLITQGATLLAHSSHQRFLYGLPEEDQEKGRTSG
What is the function of this protein?
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens.  Macrophage-specific membrane transport function.  Controls natural resistance to infection with intracellular parasites.  Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes (By similarity).
What are the official names of this protein?
Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPPH_BURMA
Sequence: MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: SYT_MYCTU
Sequence: MSAPAQPAPGVDGGDPSQARIRVPAGTTAATAVGEAGLPRRGTPDAIVVVRDADGNLRDLSWVPDVDTDITPVAANTDDGRSVIRHSTAHVLAQAVQELFPQAKLGIGPPITDGFYYDFDVPEPFTPEDLAALEKRMRQIVKEGQLFDRRVYESTEQARAELANEPYKLELVDDKSGDAEIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIPAFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDRHLEFIEEAQRRDHRKLGVELDLFSFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWYADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLTMDDAHIFCTRDQMRDELRSLLRFVLDLLADYGLTDFYLELSTKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQMSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDDRMAKKIVHHTNHKVPFMVLAGDRDVAAGAVSFRFGDRTQINGVARDDAVAAIVAWIADRENAVPTAELVKVAGRE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3295_ARATH
Sequence: MSTQATGPSSTSGRRSNSTVRRGPPPSKKPVQSENGSVNGNTSKPNSPPPQPQSQAPSNGERTVKKLRLSKALTIPEGTTVFDACRRMAARRVDACLLTDSSALLSGIVTDKDVATRVIAEGLRPDQTLVSKVMTRNPIFVTSDSLALEALQKMVQGKFRHLPVVENGEVIALLDITKCLYDAISRMEKAAEQGSALAAAVEGVEKQWGSGYSAPYAFIETLRERMFKPALSTIITDNSKVALVAPSDPVSVAAKRMRDLRVNSVIISTGNKISGILTSKDILMRVVAQNLSPELTLVEKVMTPNPECASLETTILDALHTMHDGKFLHLPIIDKDGSAAACVDVLQITHAAISMVENSSGAVNDMANTMMQKFWDSALALEPPDDSDTQSEMSAMMHHSDIGKLSSYPSLGLGNSFSFKFEDLKGRVHRFTSGAENLEELMGIVMQRIGSDNNNVEQRPQIIYEDDEGDKVLITSDSDLVGAVTLARSTGQKVLRLHLDFTESTRSLSSETTQLKKGDSRDRGSGWVSWRGGVVVTGAVVLTSIAIVVYLKRSKN
What are the official names of this protein?
CBS domain-containing protein CBSCBSPB3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YO17_AMEPV
Sequence: MQNNDNYYSDIEGAKSDISLVDRKKKIGKMINNIVNINNELNKQLSNNNKMLKNLLDSLKKYDCCL
What are the official names of this protein?
Uncharacterized protein AMV017/Q1.
Protein: TUSB_ERWT9
Sequence: MLHTLMTSPFRCDLSAILRLLAAGDDVLLLQDGVIAALDGSAPLEALLKAPINLYVLKEDLEARGLLAQISPRATVVGYTDFIQLAVRNPQQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSRA_STRCO
Sequence: MSCGEPHETDCSEILDHLYEFLDKEMPDSDCVKFEHHFEECSPCLEKYGLEQAVKKLVKRCCGQDDVPGDLRAKVMGRLDLIRSGQSVPEHDVAAAPSSSAPQES
What is the function of this protein?
A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress.  Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible.  Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR.  In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH.  Probably releases SigR during oxidative stress.
What are the official names of this protein?
Anti-sigma factor RsrA, Regulator of SigR, Sigma-R anti-sigma factor RsrA.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
Protein: PSME2_RAT
Sequence: MAKPCGVRLSGEARKQVDAFRQNLFQEAEDFLCTFLPRKIISLSQLLQEDSLNVADLSSLRAPLDIPIPDPPPKDDEMETEQEKKEVPKCGFLPGNEKLLALLALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTAISKYFSERGDAVAKASKDTHVMDYRALVHERDEAAYGALRAMVLDLRAFYAELHHIISSNLEKIVNPKGEEKPSMY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
What are the official names of this protein?
Proteasome activator complex subunit 2, 11S regulator complex subunit beta, REG-beta, Activator of multicatalytic protease subunit 2, Proteasome activator 28 subunit beta, PA28b, PA28beta.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: METN_ALBFT
Sequence: MIQLKDISLSYPGHPAPVQALQGVNLQVRAGEVFGVIGRSGAGKSSLIRVINLLNRPSQGQVHVAGAELTALSASALRAARHQIGMIFQHFNLLSSRTVFDNVALPLELSGVRPALIRARVDELLDLVGLSALRERYPAQISGGQKQRVGIARALASKPKVLLSDEATSALDPETTRSILGLLRQINRDFGLTIVLITHQMQVIKQVADRVAVIDAGRIVEQGAVIDVFTRPQHATTRSLIDEILPQELPLSVIARIRALMAAEPQRSGQLLRLAFAGDGSGQPLLSDVIRRFGLDLNILHGQIDDIQGQTFGSLAVHVRGASAQLVQAVAHLRSAGVVVQEEEIAHV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y981_YERPP
Sequence: MGYFIDRRLNGKNKSMVNRQRFLRRYKSQIKQSIADAINKRSVTDIESGESVSIPIDDINEPMFHQGNGGLRHRVHPGNDHFITNDRVDRPQGGGGGGSGQGNAGKDGEGEDEFVFQISKDEYLDLLFEDLALPNLKRNQYKQLAEFKTHRAGYTSNGVPANISVVRSLQNSLARRTAMTASKRRELRELEAALTVLENSEPAQLLEEERLRKAITELKQKIARVPFIDTFDLRYKNYERRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVDVVYIRHHTQAKEVDEQEFFYSQETGGTIVSSALKLMDEVVQERYNPAQWNIYAAQASDGDNWADDSPLCHELLAKKILPVVRYYSYIEITRRAHQTLWREYEDLEEKFDNFAIQHIREPEDIYPVFRELFHKQTVDN
What are the official names of this protein?
UPF0229 protein YPDSF_0981.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: HIS5_YERPE
Sequence: MDVVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQRELIELIKSCTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKMTDFGLPLPHMGWNQITAQAGNHLFRGIPDGTYFYFVHGYAMPICPNTIAQTNYGEPFTAAVEKDNFFGVQFHPERSGAAGAQLMKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_METC4
Sequence: MRPPGFWTRPPTHPLARLLAPVGRVYGGLTADRMDRPGAEPPYPVLCVGNFTLGGAGKTPTALALVRLLRDLGRTPALLSRGYGGRLAGPLVVDPARHAAAEVGDEPLLLAQAAPTIVARDRPSGARLCAASGADVIVMDDGLQNPSLTKSLSLAVVDGGVGLGNGLPFPAGPLRAPLARQWPHVAGLVLVGEGSPGEAMAAEAESRGLPVHRARLVPEAGSDWAGRRVVAFAGIGRPQKFFETLRSLGAEIVAEWAFPDHHPYRPGDWTALSALAAREGASLVTTEKDAVRLPAEARTAVAVLRVALAFADETRLRQQLAAAFPRA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PKHS1_HUMAN
Sequence: MAGGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIETDGPDQVSGRIECHYEPMESSFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWCLSPADVEAQTTNDQKGNIPDESQVEKLNVFLSPPDVINYLALTEATGRICVSQWEGPPRLGCIFCHGDHLLAVNDLKPQSLEEVSLFLTRSIQKEDSFRILSYQVAFGEGTELRDRAPGFRTSDRHDVAKRACMESDWCRDSKTAPSTNLCLSFLFCKIMTNDGAGCWIIK
What are the official names of this protein?
Pleckstrin homology domain-containing family S member 1, PH domain-containing family S member 1, Epididymis luminal protein 185, hEL185.
Protein: OBG_BACLD
Sequence: MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRYQRHFKAARGEHGMSKNQHGRNAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGGRGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKLTDDYPVFPISAVTRQGLRDLLFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEISRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGMGVDDALRARGAKDGDTIRLLEFEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA1_SULOH
Sequence: MRIVYDDVRDLKAIVQALLKLVDEALFDIKPEGIQLVAIDKAHISLIKIELPKEMFKEYDVPEEFKFGFNTQYMSKLLKAAKRKEEIIIEADSPEVVKLTLSGALNRVFNVNNIEVLPPEVPEVNLEFDIKATINASGFKNAIGEIAEVADTLLISANEEKVIVKGEGENKVEVEFSKDTGSLADIEFNKESSSAYDVEYLNDIISLTKLSDYVKVAFAEQKPMQLEFNMEGGGKVTYLLAPKLS
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen homolog 1, PCNA 1.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RF1_ALISL
Sequence: MKASIRVKLETLVERYEEVQHLLGDPGVIGDQNKFRALSREYSQLEEVTQCFQAYEKVQEDLVAAQEMAQEDDAEMREMAQDEIKEAKEASERLTDELQVLLIPKDPNDERNCFLEIRAGAGGDEAGIFAGNLFRMYSRFAEKKGWRIEVMSSHASEQGGFKEMIAKVSGDGAYGILKFESGGHRVQRVPETESQGRVHTSACTIAVMAEIPEADLPEIKSSDLKIDTFRSSGAGGQHVNTTDSAIRITHLPTGTVVECQDERSQHKNKAKAMSVLAARIIQAEEARRAAVVSDTRRNLLGSGDRSDRIRTYNYPQSRVSDHRINLTIYRLNEVMEGDLAALIEPVVLEYQADQLAALAEQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPL_DICDI
Sequence: MKSITKIFLILGLFAFLLVAFAPSSSVATVNLESDGYTEAEAKLIEEKGEKFTFQTEVNKLMNIIINSLYSKKEIFLRELISNASDALDKIRFLALTNADLLGEGEQSNLDIHIKIDKANNVLHITDRGVGMTKDELVRNLGTIAQSGTKEFIKKVSDSAESSNLIGQFGVGFYSLFLVADSVVVTSKSNDDDQYVWTSDSQSSYTIAKDPKGNTLGRGTRISLHIKDDSKEFLDQEVIKQLVKKYSQFINFPIYLYVSEEVEIPKEEQEDSKPITDDQVEETTTTTEEGEEETTTEEEGQTEEKKTKTVYKWEELNDSKPLWMKAAKDVTKEEYTEFFRSLSKTQDTPITYSHFKTEGDTEFRSILYIPENPPSNMFDLEAAGSGLKLFVRRVFITDNLKELVPNWLRFLVGVIDSDDLPLNVSREMLQQNKILDAIKKKVILVKFISMIKELSEDEDKTKYNEFFKKFGSSMKLGAIEDQANKKRLTKYLLFPSSKEELTTFAGYVERMKEGQDQIYFITGKSKDSVEASPLIEQAIKKGYEVLFLVDPIDEYLVPQLDKFDDKYKFTNLARSGVKFNEDKEEEDQRKQTAEEFKPLLSYLKKTLSDKLEKVVISKVLADSPSILVSNSWGVTANQERIMKAQAHQANAQPQFNSKKIMEINPSHPLIKKLLNRLNEFGEEDETTKVSAHVLYETSALTAGYSIDNPTNFADFIYKLMMINGDSLAQTNFETTKNENSGPSVSFGDDDENQQQDFQQPPQSTHDEL
What is the function of this protein?
May play a role in late differentiation as well as in starvation response.  When overexpressed, suppresses the ability to form normal fruiting bodies and impairs prespore differentiation as well as maturation into spores.
What are the official names of this protein?
Endoplasmin homolog, 92 kDa phosphoprotein, Glucose-regulated protein 94 homolog, GRP-94 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Note=In prespore cells, preferentially localizes in Golgi vesicles and cisternae. Colocalizes with trap1 in the prespore-specific vacuole.
Protein: VMPA2_LOXIN
Sequence: MIPDVGFLVLLTGALFICIKAAPATTDVDPTFEGRIVMEGDILIREEQLTERNAIALENMRWPDATIVYKLTGWYALFPGDIKKAMRHIEENTCIKFKARSNEEGYVKIYKGEKESCFADIGYFASEQRLSLGSGCKIFGRILHEMGHTIGLFHEHTRPDRDNYITVHEDNIRPGSKRNYRKTPSYMTRVIGPFDYDSIMIYGETAGSRDPMHLKSMEANKPGVTLISSRYKDRLTDLDIKKINTLYNCPGKEKFS
What is the function of this protein?
Zinc metalloprotease.  Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro.  Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins.  Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey (By similarity).
What are the official names of this protein?
Astacin-like metalloprotease toxin 2, Loxosceles astacin-like protease 2, LALP2.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS22_SACEN
Sequence: MGLQEHPVTPAERQPPVRGGVTIGVEEEFLLVDAASGQLAPHAEAVLAEAANGPLGAPDAVLHAEMLNSQVEAATGCCRTLEELRSQLVAARTSLDRAASVAGARIVSSGTPVLAVEGTGTSNGQRFADIAERYRAVASDYHVCGCHVHVGVPDRDTAVAVVNHLRPWLPTLLAISANSPFHLGHDTGHASWRGVQQRLYPGSGVPPHFPSRDAYDREVARLVDCGALVDDRMSFWMARPSPHLPTVELRVADALITAEETVLQAALSRALVRAALDDLAAGREGDEVSDQVAAAAVWNASRYGLRGPAVDPVPARRVPALEMVERLLRRVGPALEQTGDSALVREALAHVTGVGTGSERQRAAAAAGGPREVVAMLAAATAPGRADRLRT
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: LRC42_XENLA
Sequence: MFQCLEPERNEEAGLVYVREKGKLSVIGSHSSELRTRPCRLFSKGFSVELCGKQEDTSKHRQKPFIFTYTKEGSLRYSAKSLFTLTLELISDNIQYVDSLMGFPDQIAEKLFTAAEAKQKFYAPCSGLMALRKFTEAYGDLVLSSLCLRGRYLLVSERLEEIKSFQCLHSLDLSCCKLGDEHELLAHLSSDPMSSLTELYLKDNCLSNIGIQKMTASVRVLGRGLDKLKVLDLSSNPGITDRGVCFLFGFKLLKFLDLSDTSIQDPSGTLKKIETKIGLVLSKKSIFQFDHTNCRTQGWAEQLLEQWESYILSAIKPKDTLKSRNAAQQFYGKEKKQIPSDSGTFTLPAPVVQKQTHLQFFRPKEQKDPDSSNSEKRRHSTKRTGADCVQEDCSIAPSTKRPRVTLTSSDWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.