PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_RALSO
Sequence: MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGRIQSLACDYWEMQVDVQFVLDPTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARPTMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAPAAPAVMGGLSAPPAAPVDDTVHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILAYSNFHGKEITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_SHESR
Sequence: MSLSTEAKAKILAEFGRGANDTGSTEVQVALLTAQINHLQDHFKEHIHDHHSRRGLLRMVSARRKLLAYLKRTEAARYNELIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ATPD_HELMI
Sequence: MLTGAVARRYAQALLEIGIQTKTLDALEGELGRFVEMIGHPELQRFLFHPSIVVAEKKDLVGRLLATGAFSETARAFILLVIDRRRESYFADIFREFVRLANKVRNIEEARVTSAVELAPEQVERLRSQLAAATGKAIVLRMAVDPDLIGGLVVAFGDRIIDGSVAGKIRDLRESLLRSPLPSLS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS16_CORDI
Sequence: MAVKIKLQRLGKIRTPHYRVVVADARTRRDGKVIENIGIYEPKQDPSVIKIDSERAQYWLGVGAQPTEPVLALLKVTGDWQKFKGLEGAEGTLKVAEPKPSKLELFNQALAEANEGPTAEAITEKKKKAKEEAAAKAAAEAEAAAKAEEAPAEEAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PYRG_MYCTO
Sequence: MRKHPQTATKHLFVSGGVASSLGKGLTASSLGQLLTVRGLHVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLPGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDEIKRRILAMAQPDADGNRPDVVITEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSLVPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVISTPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLVRRVHEPHETVRIALVGKYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSGAAAALGDVHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARSVGLTNANSAEFDPDTPDPVIATMPDQEEIVAGEADLGGTMRLGSYPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDKIAESGLRFSGTSPDGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAIDYKAGELLPVEIPEIPEHTPNGSSHRDGVGQPLPEPASRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y034_UREPA
Sequence: MLISKHEERVKSILSARMENGNLRSRENTQVEFKQSFNKGNIAIYAKTMAAFSNNSGGYIIFGIKDSPRSIIGLQNSNFENIQQEDLTDSINNLFSPSINWELGSFILKEKEINSNGDVIIVQKIIGWIYTEESNIKPVIAQKNNSSEKIVNGDIFYRYRARTEKIKYAEMEQIINCRMKQERDSLFKVFEFIRNNGATNLGIVDYNNGKLSTPYGVDVVLEKNLIAKLLKKAKFIKEGSFSENEGIPVIKVTGNINLAEEVPVPLENLDETYPYIQKQLAEKLNITPQKLYALIWYFKMKESKKYHLEITTSKTNKTHKFSKFALLFLKEKIIELDENKNELNNIISKFNNRKK
What are the official names of this protein?
Uncharacterized ATP-binding protein UU034.
Protein: DNAA_SALCH
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNTFCGADAPQLRFEVGTKPVTQTLKTPVHNVVAPTQTTTAQPQRVAPAARSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKIADLLSKRRSRSVARPRQMAMALAKELTNYSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_PARDP
Sequence: MTTITPEAARLRLAQYLSPAFPTGGFAWSQGLEWAMDQGAVTRATLPQWLEDWLDHGAGWCDAVLLSLALRRGADHAELDDLARAMCPCARRLAETVEQGTAFAANVAALTGRPQSAAALPVAVGRACGCLPLPAGEIIGLYLQAQAAALISAAVRFLPLGPVEGQAMLAGLQPALLAAAARAGTADPKDLASATWGADLAAMRHETMVTRIFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ECOL5
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNNPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEKDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP2_ARATH
Sequence: MMRGLVSGAKMLSSTPSSMATSIATGRRSYSLIPMVIEHSSRGERAYDIFSRLLKERIICINGPINDDTSHVVVAQLLYLESENPSKPIHMYLNSPGGHVTAGLAIYDTMQYIRSPISTICLGQAASMASLLLAAGAKGQRRSLPNATVMIHQPSGGYSGQAKDITIHTKQIVRVWDALNELYVKHTGQPLDVVANNMDRDHFMTPEEAKAFGIIDEVIDERPLELVKDAVGNESKDKSSS
What is the function of this protein?
Component of the mitochondrial ATP-dependent Clp protease (PubMed:11352464).  Cleaves peptides in various proteins in a process that requires ATP hydrolysis (By similarity).  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, mitochondrial, ATP-dependent Clp protease proteolytic subunit 1, mitochondrial, Endopeptidase ClpP2, nClpP7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHY3_PAGMA
Sequence: FIGLLISAGKAIHDLIRRRH
What is the function of this protein?
Has antibacterial activity against Gram-positive bacteria B. subtilis ATCC 6633, L. garvieae ATCC 49156 and S. iniae F-8502, and Gram-negative bacteria E. coli WT-2, V. anguillarum ATCC 19264, V. penaeicida KHA, V. harveyi ATCC 14126, V. vulnificus ATCC 33148, A. salmonicida NCMB 1102 and P. putida ATCC 12633.  Has hemolytic activity against human red blood cells.  Seems to disrupt the membranes by adopting an alpha helical conformation.  May play a significant role in innate host defense.
What are the official names of this protein?
Chrysophsin-3.
What is the protein family that this protein belongs to?
Belongs to the pleurocidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: H9D01_CYRHA
Sequence: MKSIVFVALFGLALLAVVCSASEDAHKELLKEVVRAMVVDKTDAVQAEERECRWYLGGCSQDGDCCKHLQCHSNYEWCIWDGTSSK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Omega-theraphotoxin-Hhn1c, Omega-TRTX-Hhn1c, Hainantoxin-IX-4, HNTX-IX-4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 17 (Hntx-9) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YGAC_BACSU
Sequence: MGYPKEGETIQIHSYKHNGLIHRIWNETTILKSTEMCVIGANDRTMVTESDGRTWITREPAICYFHARQWFNVIGMLREDGVHYYCNISSPFAYDGEAIKYIDYDLDVKVFPDMTYNILDEDEYDDHRKAMNYPKEIDSILRDYLNTLLHWIHQRQGPFAPEFVDMWYERYLRYTK
What are the official names of this protein?
UPF0374 protein YgaC.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: AES_SHISS
Sequence: MKPENKLPVLDLISAEMKTVVNTLQPDLPSWPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKIAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YN8C_SCHPO
Sequence: MSQDQKPKVLEVSNLENQDAKWTSLKKIRWQDEKGKIRFWEMAERTTRSEANVDAVAILAIVPIDGSPHVLCQKQFRPPIGKFCIEIPAGLVDSKESCEDAAIRELREETGYVGTVMDSTTVMYNDPGLTNANLKIILADIDMSKPENQNPQQQLDDGEYIENFPIKLSSLQEELFSLEKKGFAIDVRLSTFALGLHAGLKYLSS
What are the official names of this protein?
Uncharacterized Nudix hydrolase P35G2.12.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DTD_RUEST
Sequence: MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAGKMNRSVSDTSGAVLVVSQFTLGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTVQTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYUG_RAT
Sequence: MDVFKKGFSIAREGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKGERGTSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIVVTTGVVRKEDLEPPAQDQEAKEQEEGEEAKSGGD
What is the function of this protein?
Plays a role in neurofilament network integrity.  May be involved in modulating axonal architecture during development and in the adult.  In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases.  May also function in modulating the keratin network in skin.  Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
What are the official names of this protein?
Gamma-synuclein, Persyn, Sensory neuron synuclein.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle (By similarity).
Protein: ISPF_CLOB8
Sequence: MRIGLGYDVHRLVENRKLILGGVEIPYEKGLLGHSDADVLIHAIIDSLLGACALGDIGKHFPDTDSRFSGISSIILLEETGKLLLKSGYAINNIDATIIAQKPKMLPHIENMRKNISIALNIDINKINIKATTEEGLGFTGEMLGISSQSISSVESII
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LBD7_ARATH
Sequence: MSLSTFSGGSTTACAACKHQRKKCKKNCILARYFPQDGTNKFLNAHKLFGVSNITKMLKRIEESQRDIAMENLIYHANARALDPVGGVYRTICDLKCKIEFVQTELNLTRQQIDMCRSLAQEQHRQRQNLPYRCNSFESLLQQDGDEYVNVDGLDHQNMQQQQEMQQQQQNPSNYDMFLEMPEQTSKVKLEEEKISDQRKNNLMRQILMSSAII
What are the official names of this protein?
LOB domain-containing protein 7, ASYMMETRIC LEAVES 2-like protein 31, AS2-like protein 31.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: YBGE_ECOL6
Sequence: MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTSELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF
What are the official names of this protein?
Uncharacterized protein YbgE.
Protein: PSAJ_ADICA
Sequence: MQHVKIYLSTAPVVATIWFGLLAGLLIEINRFFPDALLFPFP
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: F220A_HUMAN
Sequence: MRDRRGPLGTCLAQVQQAGGGDSDKLSCSLKKRMPEGPWPADAPSWMNKPVVDGNSQSEALSLEMRKDPSGAGLWLHSGGPVLPYVRESVRRNPASAATPSTAVGLFPAPTECFARVSCSGVEALGRRDWLGGGPRATDGHRGQCPKGEPRVSRLPRHQKVPEMGSFQDDPPSAFPKGLGSELEPACLHSILSATLHVYPEVLLSEETKRIFLDRLKPMFSKQTIEFKKMLKSTSDGLQITLGLLALQPFELANTLCHS
What is the function of this protein?
May negatively regulate STAT3.
What are the official names of this protein?
Protein FAM220A, STAT3-interacting protein as a repressor.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_CAEEL
Sequence: MATDQKRGLLIVFEGLDRSGKSTQAKRLVESINKKSTESGDASSSPSAVLQAFPDRSSSIGKLIDQYLRKEIDMDEHALHLLFSADRFSKNQMIRDNIAKGIDVICDRYCYSGVAYSLAKGLPEQWVRSSDVGLPKPDAVLFFDVSPEVAAQRGGFGEERLETATIQQKVAAVMPTLRDDAYWKTVNADGDLDSVEKNVFRIYENLDREKPFESLEKI
What is the function of this protein?
Catalyzes the conversion of dTMP to dTDP.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GPMA_STRZJ
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SYY_DEHMC
Sequence: MNQSENQIDQILKRGVAEVIVEEDFKKLLLSGRKLRLKEGFDPSSPDIHLGHMVALRKLRQLQDLGHQVVLIVGDWTAQIGDPSGASVTRPMLSAEQVKANAKTYLEQFFKIVDKDKTEVRWQSEWYGNFKLEDVVRLSSKFTVAQMLARDDFAKRYAAGKPISVTELLYPMLQAYDSVMVKSDVEFGGTDQKFNLLVGRELQEMVGQKPQQVLMVPILVGTDGVHKMSKSLGNYIGVAEDPSEIFGKCMSIPDELILQYFELVTDIPDQEIADFKAQMENGQVNPMILKKRLASELLTQLYNATAAQEADARFTRVVQRGEIPEDMPECRLENGQNTGVIDFIILSGLAKSKSEARRLLEQGAVEINSEKISDQNTPVKCGDIIKAGKRRYSKAI
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIMA1_MOUSE
Sequence: MPQLRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRMWAGWQVEVVDTPDIFSSEIPRTDPGCVETARCFVLSAPGPHALLLVTQLGRFTMQDSQALAAVKRLFGKQVMARTVVVFTRQEDLAGDSLQDYVHCTDNRALRDLVAECGGRVCALNNRATGSEREAQAEQLLGMVACLVREHGGAHYSNEVYELVQDTRCADPQDQVAKVAEIVAERMQRRTRLLAGLWGWRKFYWKGWRRGFSVFLGVAILIYLLFYRKGFGDQNNR
What is the function of this protein?
May regulate lymphocyte survival.  Required for normal levels of mature T-lymphocytes and mature B-cells.
What are the official names of this protein?
GTPase IMAP family member 1, Immune-associated protein 38, IAP38, Immunity-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: MARC2_RAT
Sequence: MGSSSSTALARLGLPGQPRSTWLGVAALGLAAVALGTVAWRRARPRRRRQLQQVGTVSKVWIYPIKSCKGVSVCETECTDMGLRCGKVRDRFWMVVKEDGHMITARQEPRLVLVTITLENNYLMLEAPGMEPIVLPIKLPSSNKIHDCRLFGLDIKGRDCGDEVARWFTSYLKTQAYRLVQFDTKMKGRTTKKLYPSESYLQNYEVAYPDCSPIHLISEASLVDLNTRLQKKVKMEYFRPNIVVSGCEAFEEDTWDELLIGDVEMKRVLSCPRCVLTTVDPDTGIIDRKEPLETLKSYRLCDPSVKSLYQSSPLFGMYFSVEKIGSLRVGDPVYRMVD
What is the function of this protein?
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles.  As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability.  May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis.  Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
What are the official names of this protein?
Mitochondrial amidoxime reducing component 2, mARC2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome.
Protein: ADHC_MYCTO
Sequence: MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFVIDISAL
What are the official names of this protein?
NADP-dependent alcohol dehydrogenase C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: HLY1U_STAUR
Sequence: MSGIVEAISNAVKSGLDHDWVNMGTSIADVVAKGADFIAGFFS
What is the function of this protein?
Virulence factor.  Causes hemolysis of erythrocytes.  Acts synergistically with beta-hemolysins from S. aureus ATCC 25923.  Cytotoxic towards human dermal fibroblasts.
What are the official names of this protein?
Hemolysin H1U.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2870_AROAE
Sequence: MRIDHIRQRLRASGAKPCHEQRVLRAWTHALPLDRGRCRSEDFFPAPLGARLPALGAELAALAQVRSEHAGEDGARLLVELADGQTVESVLLPRDGLCVSTQVGCAVGCAFCMTGRDGLLRQLGSAEIVAQVVLARSRRAVRKVVFMGMGEPAHNLDNVLEAIALLGTEGGIGHKNLVFSTVGDRRVFERLPQGSVKPALALSLHTTRPALRTKLMPRAPRLDPAELVELGETYARATGYPIQYQWTLLAGVNDDDEELDGIVRLLAGKYAVMNFIPYNSVAGAGFARPSWEHAAAMARYLHRRGILTKLRHSAGQDVDGGCGQLRARVIASGALGQPAEAAPDRVVLVRRGQA
What are the official names of this protein?
Probable RNA methyltransferase AZOSEA28700.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1882_STRZP
Sequence: MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAVRTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK
What are the official names of this protein?
UPF0154 protein SPP_1882.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS12_FLAJ1
Sequence: MPTIQQLVRTGRTQITKKSKSVALDSCPQRRGVCTRVYTTTPKKPNSAMRKVARVRLTNGNEVNAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGALDTSGVAGRTQRRSKYGAKRPKEAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CPT1A_HUMAN
Sequence: MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK
What is the function of this protein?
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed:9691089, PubMed:11350182, PubMed:14517221).  Plays an important role in hepatic triglyceride metabolism (By similarity).
What are the official names of this protein?
Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.