PharMolix/UniProtQA huggingface dataset:
Protein: PBCG_MESAU
Sequence: MMLPMTLCRMSWMLLSCLMFLSWVEGEESQKKLPSSRITCPQGSVAYGSYCYSLILIPQTWSNAELSCQMHFSGHLAFLLSTGEITFVSSLVKNSLTAYQYIWIGLHDPSHGTLPNGSGWKWSSSNVLTFYNWERNPSIAADRGYCAVLSQKSGFQKWRDFNCENELPYICKFKV
What is the function of this protein?
Constituent of ilotropin, which is a partially purified preparation of cellophane wrapping (CW) pancreata.  Capable of initiating duct cell proliferation, a prerequisite for islet neogenesis.
What are the official names of this protein?
Pancreatic beta cell growth factor, Islet neogenesis-associated protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_BLOPB
Sequence: MIDDNGYRLNVGIVLCNTHQQVLWARKYKQHYCWQFPQGGINIGETPEQAMYRELFEEIGLNYQDVRILSSTQYWMHYKLPKKLIRWKIRPICFGQKQKWFLLKLLSKDTRINIKSNKDYTFDRWKWVSLWYPIRRVVFFKRDVYRKVMQEFVDVIIS
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CUL1_ORYSJ
Sequence: MATHERKTIDLEQGWEFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCTQKPPHDYSQQLYEKYRESFEEYITSMVLPSLREKHDEFMLRELVKRWSNHKVMVRWLSRFFHYLDRYFISRRSLPQLSEVGLSCFRDLVYQEIKGKVKSAVISLIDQEREGEQIDRALLKNVLDIFVEIGLTSMDYYENDFEDFLLKDTADYYSIKAQTWILEDSCPDYMLKAEECLKREKERVAHYLHSSSEQKLLEKVQHELLTQYASQLLEKEHSGCHALLRDDKVDDLSRMYRLFSRITRGLEPVSQIFKQHVTNEGTALVKQAEDAASNKKPEKKEIVGLQEQVFVRKIIELHDKYVAYVTDCFQGHTLFHKALKEAFEVFCNKGVSGSSSAELLATFCDNILKKGGSEKLSDEAIEDTLEKVVRLLAYISDKDLFAEFYRKKLARRLLFDKSANDEHERSILTKLKQQCGGQFTSKMEGMVTDLTVARDHQAKFEEFISTHSELNPGIALAVTVLTTGFWPSYKSFDINLPAEMVKCVEVFKEFYQTRTKHRKLTWIYSLGTCNINAKFEAKTIELIVTTYQAALLLLFNGVDRLSYSEIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPNNRSISPNDVFEFNSKFTDKLRRLKIPLPPVDEKKKVVEDVDKDRRYAIDASIVRIMKSRKVLGHQQLVMECVEQLGRMFKPDFKAIKKRIEDLITRDYLERDKDNPNVYRYLA
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Cullin-1, OsCUL1, OsCUL1-1.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: RL10_SALHS
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CMOA_CHRSD
Sequence: MTRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRRSVPGYGQILGMLGLIAERHLRFGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTMVARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFTLQFLPPEDRRAVIERLYAALEPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAHHERLHEAGFTRVSTWFQYLNFASMVAFKDA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: APOA1_MACFA
Sequence: MKATVLTLAVLFLTGSQARHFWQQDEPPQTPWDRVKDLVTVYVEALKDSGKDYVSQFEGSALGKQLNLKLLDNWDSVTSTVSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELHEGTRQKLHELHEKLSPLGEEVRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKASEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLSTQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBA7_HUMAN
Sequence: MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL
What is the function of this protein?
Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.  Catalyzes the ISGylation of influenza A virus NS1 protein.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: HMN6_HUMAN
Sequence: MTPRGFSCLLLPTSETDLPVKRRT
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 6, HN6, MT-RNR2-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: VIRD3_AGRRH
Sequence: MANEEFTGHFARPAPVANDEGRRTTSTSIPAHAMAAREDGRDTSVAVTLSRPPNSGIPHGIPETSASGRRLVAAHPQDAAMPLGLSETRTDLPAILRKNNGDFRTAMQHWRELLHENPDKRDREASALPDLGARGIKRPREIEHPGDANRSVTRREIGLGREIDTVAASSLVNRDTWVAHSSNGQGGPQAGVYNVQPSADRAQETSQESSTLPDPTSVSALYSGPPSEWVGRDTGYETDRNSGDTISAPIRGLEELEDSADSRYFGHEAQSLSANVTTSISNAEASSHSEHTEILDDVSSARSGEQGRGGDGGAILGFSHDLSPHPQRLPQTTPDDFPELTNAAMAEIDAIFESLSQKSLARESAAPVLHEPVSGDAFQKEGTSDRADGMPSNGEPPVEQAGGHLPQALRSSGAELDDFSWLTDAALAEIDALIKSHSNRSSSVRNAAPDLRGAGLDNAVGKDSVIEHAEKISIDSPRPARLNGERSPKAQKSSQASLADFPDLTDAEWAHIEETERIAITAIEKGKQKISTKADTRSGFGNSSVPQVGNRSGAPMVPNTNQPIPSWYHKAENISNGLVEDTHITPAVVSSRRRNDAENASTRFGDPAPALRHYNLGRTLEATPVRDVISGTSRDRGLTAHAADQLAIDDSRKRTDRDRKTQPYIRGLDSRSREGYGR
What are the official names of this protein?
Protein VirD3.
Protein: RLMG_ECOUT
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_YERE8
Sequence: MKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEAIPVRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRGQNRYTILENGTFTSCLPGDNSWSVVGSEVIHDREEQVAEIWNARFKIGKVPVFYSPYMQLPVGDKRRSGFLIPNAKYTSNNGLEFMLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPSDRLYHGTDGTEKDPTRWLYYWGHSGVMDKVWRFNVNYTRVSDPDYFTDLTSQYGSTTDGYATQIFSVGYADQNWDATLASKQFQVFTTGGNNNAYRAQPQLDMNYYKNDIGPFDLHIYGQAAKFTSVNPENPEAERFHIEPSINLPLANGWGSLNTEAKLLATHYQQDIPNGFASNYKNQNGQDATVPNLKDSVNRVIPQFKVDGKVVFDRPMDWSEGFTQTLEPRVQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDELVERFNVSVGQIYYFSRSRTGNSETIDNSDDTGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAVMEYRKDAERMIQLNYRYASPEYIQAAVPNVKSPGYQQGISQIGTTASWPIADRWALVGAYYYDTKANQPASQLVGVQYNTCCWAINLGYERKITGWNNQNETSKYDNKVSFNIELRGLSSDHSLGTAQMLGSGILPYQSAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ML168_ARATH
Sequence: MVEAEVEVDVEIKSTADKFFMFSRRSQHASKATRYVQGCDLLEGEWGEVGSILLWKLTVDGEPKVSKDMIEAIDMKMNMIQWRVLEGPLKEEYNIFSKTMKVSPKQGGSGSVVKWNLKYERIDEKVAHLERLLQFFVECVNEIDQYLLSEG
What are the official names of this protein?
MLP-like protein 168.
What is the protein family that this protein belongs to?
Belongs to the MLP family.
Protein: CHED_BURM9
Sequence: MSGLPIATNLYFDAHFHRHGVKLLPNEFYTTREDMVLVTVLGSCVAACLHDPIGRIGGMNHFMLPDDGADPSAAASESMRYGAYAMEVLINELIKAGGRRERFEAKVFGGAAVLAGMTTINIGDRNADFVRRYLALERIRITAEDLQGVHPRKVAFMPHTGQAMVKKLRVQAPDVAAREAALAREAVDPHGERAPRVRPRVELFGTPAPKAQAKPRIELFGMRATQPATRKQEA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: SYH_LISMO
Sequence: MDLQLPRGTRDILPEEVSKWHFLETEFKNVCENYQYEEIRTPVFEHTELFERGVGDSTDIVSKEMYTFQDKGGRSLTLRPEGTASVVRAFVEHKLYGEVSQPIKMYYNEPMFRYERPQGGRQRQFTQMGIEALGSDDPSIDVEVISLAMEFFRKIGLTNIKLVINSLGDKESRLKHREALVAHFEPHIDEFCAECQVRLHKNPLRILDCKKDHDNPLIQSAPSILDFLNEESVAYFENVKNYLNALEIPFEIDPTMVRGLDYYNHTTFEIMSVEEGFGAKTTLCGGGRYHGLVREFGGPDTPGMGFGIGVERILLALEKADIEIPAKKPLEVYVITAQPEAELKGVTLVNKLRQNGISAEKDYLKRKFKAQLKDANRKNAVYTIILGEEELQTGNYQLKNMETGEQEAVSETTILEKLSNTKGEK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APBC_METMP
Sequence: MAEECSGNCDSCGSSSDCSDTKKMMEQQNAQIRDNMSKIKYKIAVMSGKGGVGKSTVTVNLAATLNMMGYKVGVLDGDIHGPNIPQMLGVDQIQPMADENGIYPVSTPQGIKTMSIGYFLPDKNTPIIWRGPKASGAIRQFLSDVNWGELDFLLIDTPPGSGDIQITTLQAIPDIDGVVIVTTPEEVSVLDARKSVSAANTLEIPIIGIVENMGGFVCPECDKVIDIFGKGGGEKAAKELNVFFLGRIPLDIKARVASDRGVPMVTMDCKASEEFKKVVNTVLERIKKE
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: UVRC_PARPJ
Sequence: MTEPEATDAFEPKKVLAQLPHLPGVYRYYDTHGAVLYVGKARDLKKRVSSYFTKTLLSPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVAAINEEDYARDVANASRFLLGRQGEVMKELEQKMHAFASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTADEGGLQEDDAALASVALASNSLAGDDVIDDETAALADTADALAIAQEMPSEDEENEQNDAAEEVDVAEEAGSEPAKPRKGRAATGGIEAEVLEAFIAQHYLGNRVPPVLVVSHAPANRELVDVLIEQAGHKVTVLRQPQGQRRAWLTMAEQNARLALARLLSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAANAADEAAELQSDAAADPSLTPDAAEPVAAGGILPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVEDLASVEGISQALAEQIYRQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_CARHZ
Sequence: MHKGMLVVVSGPSGAGKGTICQEIRKRNPNLFYSISATTREKRVGEIDGVHYYFIDRQQFEKMIANDEFLEWADVYGNYYGTPKKPVFEALARGQDVILEIDIKGARQVKKTYPEGVFVFILPPSISILEERLRKRGTDKEEIIVKRMQMAWEEIANCDWYDYLILNDDLETAVNDLEAVLTAEKLKPKRVNYRVLLEGGVLER
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CN6LB_XENLA
Sequence: MPKEKYDPPDPRRIYTIMSAEEVANGKKSRWDELEISGRVRSLSMSLWSLTHLTVLHLSDNNLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNVVSLRELLLNNNLLRVLPFELGRLFRLQTLGLKGNPLSQDILGLYQEPDGMRKLLNYMLDNLSVHPEQLPQRPWITLKERDQILPSVPFTVMCFNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVSCDADIISLQEVETEQYYTLFMPALKERGYDGFFSPKSRAKIMSDQEKKHVDGCAIFFRTEKFSLVQKHTVEFNQIAMANSEGSEAMLNRVMTKDNIGVSVLLEVHTDFSGAGMKPHHSSEKQLLMVANAHMHWDPEYSDVKLIQTMMFVSELKSIIEKAASRPGSPTPDSNSIPFVLCADLNSLPDSGVVEYLTNGGVADNHKDFKELRYNECLTNFSCNGKNGTPDGRITHGFQLRSAYENNLMPYTNYTFDFKGVIDYIFYSKTHIDVLGVLGPLDPQWMMDNNIAGCPHPHIPSDHFSLLTQLELHPPFLPVINGVHLPSRR
What is the function of this protein?
Poly(A) nuclease with 3'-5' RNase activity.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 6-like-B.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: CFM5_GIBZE
Sequence: MFSLTKSVLFTSIVAIAAQATTAVSSPTQTSLPGLASQVPNCVAVCLRNLHESIGCDVGDIVCLCKSKASLISKVGLCVVGSQCDFEDASSSTDIVRDMCDLVAEDPGTAVIASASKVLDAVVASATTSDIEAPTSTNAAGLVAYDVVKVVVVGAAAAIAI
What is the function of this protein?
Suppresses host programmed cell death during infection by binding to Z. mays WAK17 isoform 2 and Z. mays LRR5, to prevent activation of Z. mays WAK17 isoform 1 and the downstream hypersensitive response.
What are the official names of this protein?
Effector CFEM5.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: YOHO_SALPA
Sequence: MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MOS1T_DROMA
Sequence: MSSFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKKCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVSPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKRGETVNTARYQQQLINLNRALQRKRPEYQKRQHRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYLE
What is the function of this protein?
Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism.  Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
What are the official names of this protein?
Mariner Mos1 transposase, Transposable element Mos1 transposase.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPRTL_STRPJ
Sequence: MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_RIPO1
Sequence: MYCIGLISGTSVDGIDAALIEISGTELDLKIDLISGKTYPYPPELRGKIIEICGGKPISIEELAQIDDAIAQSFAQAAIMVQNGHPHAQLIGSHGQTVFHRPPVLGEREIKLGYSLQLGRGSMIAHLTGIPTVSNFRAADIAAGGQAAPLVPKVDAYLLSHPTHHRCVQNIGGIGNVTYLPPNQKPNWEQAVRGWDTGPGNVLIDLAIQKLTNGQQTYDNNGQWAAQGTPCESLVRKWLEQEFFQQTPPKSTGRELFSPAYLEQCWQDAQPYHLSDSDWLATLTELTAASIAQSYQQFIKAPIDEILVCGGGSRNTYLKQRLANYLPNSQILTTDDLGISSDFKEAIAFGVLAYWRLVCGITGNLPQVTGAKQAMLLGDIDHPV
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ACPS_YERPA
Sequence: MAILGLGTDIVEISRIQAVVERTGERLARRILSPSEWQHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHSRAAELAVELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF122_MOUSE
Sequence: MRAVLTWRDKAEQCIYDLAFKPDGTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSSDFGLWSPEQKSVSKHKSSSKITCCSWTNDGQYLALGMANGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSREEHNDILAVADWGQKLSFYQLSGKQIGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCRVKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCRELVKKIAIYKNRLAIQLPEKILIYELYSEDSTDMHYRVKEKIVKKFECNLLVVCADHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPAGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRNKLAVVDENDTCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLDRKMFKEAYQIACLGVTDADWRELAMEALEGLEFETARKAFTRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALDMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNINEPKAAVEMYISAGEHAKAIEISGSHGWVDMLIDIARKLDKAEREPLLMCACYFKKLDSPGYAAETYLKIGDLKSLVQLYVDTKRWDEAFALGEKHPEFKDDVYVPYAQWLAENDRFEEAQKAFHKAGRQGEAVRVLEQLTHNAVVESRFNDAAYYYWMLSMQCLDMAQDPAQKDAMLDKFHHFQHLAELYHGYQTIHRYTEEPFSFDLPETLFNISKFLLHSLTKATPLGISKVNTLFTLAKQSKALGAYKLARHAYDKLRGLQIPARIQKSIELGTLTIRSKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYEVLHLVEFYLEEGITDEEAVALIDLEAPRHKREGKWRETSSNNSQTLKLDETMDSIGEDDPFTAKLSFEQGSSEFVPVVVNRSVLRSMSRRDVLIKRWPPPLQWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHACCPYCRRRIDDTGP
What is the function of this protein?
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking (By similarity).  Involved in cilia formation during neuronal patterning.  Acts as a negative regulator of Shh signaling.  Required to recruit TULP3 to primary cilia (PubMed:19000668, PubMed:21209331).
What are the official names of this protein?
Intraflagellar transport protein 122 homolog, WD repeat-containing protein 10.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to photoreceptor connecting cilia.
Protein: TVG11_HUMAN
Sequence: MPLVVAVIFFSLWVFALGQLEQPEISISRPANKSAHISWKASIQGFSSKIIHWYWQKPNKGLEYLLHVFLTISAQDCSGGKTKKLEVSKNAHTSTSTLKIKFLEKEDEVVYHCACWIRH
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) gamma chain (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
Probable non-functional T cell receptor gamma variable 11.
What are the subcellular locations of this protein?
Cell membrane.
Protein: ALR1_STAAW
Sequence: MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 1.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.