PharMolix/UniProtQA huggingface dataset:
Protein: MLP2_DROME
Sequence: MPSFQPIEAPKCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGFGTGAGTLSMDNGSQFLRENGDVPSVRNGARLEPRAIARAPEGEGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGALQSDCYAHDDGAPQIRAAIDVDKIQARPGEGCPRCGGVVYAAEQKLSKGREWHKKCFNCKDCHKTLDSINASDGPDRDVYCRTCYGKKWGPHGYGFACGSGFLQTDGLTEDQISANRPFYNPDTTSIKARDGEGCPRCGGAVFAAEQQLSKGKVWHKKCYNCADCHRPLDSVLACDGPDGDIHCRACYGKLFGPKGFGYGHAPTLVSTSGESTIQFPDGRPLAGPKTSGGCPRCGFAVFAAEQMISKTRIWHKRCFYCSDCRKSLDSTNLNDGPDGDIYCRACYGRNFGPKGVGYGLGAGALTTF
What is the function of this protein?
Plays a role in cell differentiation late in myogenesis.  Transcription factor Mef2 is essential for expression.
What are the official names of this protein?
Muscle LIM protein Mlp84B.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ASF1_EMENI
Sequence: MSVVSLLGVKVLNNPAPFTSSYQFEITFECLEQLQKDLEWKLTYVGSATSSEYDQELDSLLVGPIPVGVNKFIFEADPPDLRRIPTSEILGVTVILLTCSYDGREFVRVGYYVNNEYDSEELTADPPAKPIIERIRRNILAEKPRVTRFAIKWDTEESAPAEYPPDQPEADGLDDDGAAYGQEEAELEAALLKELQEAEKNESTKGEDHDMEGADNGEEDISDAESEDIEDESDDDEDEVDEEEGNDADEDVEMGDDSEPKDDNANPAAHHSQQEVMVH
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone asf1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECFA2_STRA1
Sequence: MGIEFKNVSYTYQAGTPFEGRALFDVNLKIEDASYTAFIGHTGSGKSTIMQLLNGLHIPTKGEVIVDDFSIKAGDKNKEIKFIRQKVGLVFQFPESQLFEETVLKDVAFGPQNFGISQIEAERLAEEKLRLVGISEDLFDKNPFELSGGQMRRVAIAGILAMEPKVLVLDEPTAGLDPKGRKELMTLFKNLHKKGMTIVLVTHLMDDVADYADYVYVLEAGKVTLSGQPKQIFQEVELLESKQLGVPKITKFAQRLSHKGLNLPSLPITINEFVEAIKHG
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: METE_BACC1
Sequence: MAIQTSNLGYPRIGLQREWKKTLEAFWSNKIDEEQFLTTMKEIRLQHVKAQQEKGIELIPIGDFTYYDHVLDTAYMLGFIPSRFSEFTSYLDVYFAMARGSKDHVASEMTKWFNTNYHYIVPEYEEGLQISLKDNRPLRLYEEAKQELGIDGKPVILGPYTFLKLAKGYTQEQFATILKQLVAPYVQLLSELHAAGAQIIQVDEPIFASLTKEEVQQAKEIYEAIRKEVPNANLLLQTYFDSVEENYEEIITFPVSSIGLDFVHGKEGNLHAISKYGFPADKTLAVGCIDGRNIWRADLDEVLTLFTTLQKQVQTKDFIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELVLIHSALTQGTESIHNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRYELQQVALKLPLLPTTTIGSFPQTTEVRQTRKEWRNGVISNEQYEQFIEKETEKWIRYQEEIGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTIKETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIRVIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAIRALDADVISIETSRSHGEFIDTLKHTTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLKVCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLLKTNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RL2_GEOSM
Sequence: MAIKTYKPTSPGRRAQTCSTFEEITACKPERSLVENLKKSGGRNSNGRITSRNVGGGHKQKYRIIDFRRDKTEIPAKVATIEYDPCRSARIALLNYADGEKRYILAPLSLKVGDTVISSEQADIKPGNALPIRCIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAKEGKYGQVKLPSGEVRMILMDCKATIGQVGNVDHENVSIGKAGRSRWLGVRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRTNKRSTPFIVKKRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: 5MP2_HUMAN
Sequence: MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD
What is the function of this protein?
Translation initiation regulator which represses repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (PubMed:29470543, PubMed:34260931).  Enhances histone H4 gene transcription but does not seem to bind DNA directly (PubMed:11524015).
What are the official names of this protein?
eIF5-mimic protein 2, Basic leucine zipper and W2 domain-containing protein 1, Protein Orf.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
Protein: IDI_SALPA
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLNYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPKL_ARATH
Sequence: MTSNRSNLLFSLVLFHFLFVPTQLQALNTDGVLLLTFKYSILTDPLSVLRNWNYDDATPCLWTGVTCTELGKPNTPDMFRVTSLVLPNKHLLGSITPDLFSIPYLRILDLSSNFFNGSLPDSVFNATELQSISLGSNNLSGDLPKSVNSVTNLQLLNLSANAFTGEIPLNISLLKNLTVVSLSKNTFSGDIPSGFEAAQILDLSSNLLNGSLPKDLGGKSLHYLNLSHNKVLGEISPNFAEKFPANATVDLSFNNLTGPIPSSLSLLNQKAESFSGNQELCGKPLKILCSIPSTLSNPPNISETTSPAIAVKPRSTAPINPLTEKPNQTGKSKLKPSTIAAITVADIVGLAFIGLLVLYVYQVRKRRRYPESSKFSFFKFCLEKNEAKKSKPSTTEVTVPESPEAKTTCGSCIILTGGRYDETSTSESDVENQQTVQAFTRTDGGQLKQSSQTQLVTVDGETRLDLDTLLKASAYILGTTGTGIVYKAVLENGTAFAVRRIETESCAAAKPKEFEREVRAIAKLRHPNLVRIRGFCWGDDEKLLISDYVPNGSLLCFFTATKASSSSSSSSSLQNPLTFEARLKIARGMARGLSYINEKKQVHGNIKPNNILLNAENEPIITDLGLDRLMTPARESHTTGPTSSSPYQPPEWSTSLKPNPKWDVYSFGVILLELLTSKVFSVDHDIDQFSNLSDSAAEENGRFLRLIDGAIRSDVARHEDAAMACFRLGIECVSSLPQKRPSMKELVQVLEKICVLV
What are the official names of this protein?
Receptor protein kinase-like protein At4g34220.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ERA_PSEMY
Sequence: MTDAPVSRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGEIQAVYVDTPGLHKHNDKALNRYMNRSASSALKDVDVVVFVVDRTRWTDEDQLVLEKVQHVKCPILLAVNKADRLEDKSELLPHLNWLAEQLPQAEIVPISALQGQNLDTLEKLVGERLPESEHFYPEDQITDRSSRFLAAELIREKIMRQLGAELPYQITVEIEEFKQDGPILHIHGLILVERDGQKKIIIGDKGERIKRIGQDARKDMETMFDSKVMLNLWVKVKGGWSDDERALRSLGYLD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: MARHA_HUMAN
Sequence: MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRNYPQPRTEENENSELGDGNEGSISQSQVV
What is the function of this protein?
E3 ubiquitin-protein ligase (Probable).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase MARCHF10, Membrane-associated RING finger protein 10, Membrane-associated RING-CH protein X, MARCH-X, RING finger protein 190, RING-type E3 ubiquitin transferase MARCHF10.
Protein: ENPP4_XENTR
Sequence: MLGRAFIVAVLYCATFCKADKPTNSSTPRLIILSFDGFRADYLTRFPMPNLDEFMKEGVQVEEVKNVFITKTFPNHYSLVTGLYAESHGIVANHMYDNDTRQVFHMNDSNSKWWDEATPIWVTNQKQGHKSGCAMWPGCNVPMHNVTLNASLNYNPNVTFTERVNNVTMWLTRPNDPINFATIYWEEPDASGHRFGPDDHDNMAKVLKEVDEHVGYLMSELKKAKLWDTVNVIITSDHGMAQCSKDRIIKLNDCIGPGNYTLVDDNPVAAILPLSDTQLVYDLLRNCHPHMKVYRKEEIPERWHYKHNSRIQPLLLVADEGWMITQNHSISMLGDHGYDNDLHSMHPFLAAHGPAFRKGYRMRTINSVDIYPLMCHILGITGLPNNGTLKDIKCLLVNQCYIQIPEAIGIVIGAIMVLTTLTCIIVMLKKKMPSTRQFSRLQFQDDDDPLIG
What is the function of this protein?
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP.  Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells.  Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase enpp4, AP3A hydrolase, AP3Aase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 4, E-NPP 4, NPP-4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CYB_GENMA
Sequence: MTNIRKSHPLAKIINESFIDLPAPSNISAWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYIHANGASMFFICLFMHVGRGVYYGSFTFTETWNIGILLMFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGVVXDSDKIPFHPYYTIKDILGLLLLTLVLMLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFSIFLILMPISGIIENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYC_SHEAM
Sequence: MLKIYNSISRQKEEFKPIQPGKIGMYVCGVTIYDLCHIGHGRTFVCFDMIVRYLRYRGYEVNYQRNITDVDDKIIKRANENGESCDSLTERLIGEMHADFDALNMVRPSFEPRATLHIDEIIDMVTRLLDRGHAYVAADGDVLFDVSSYAAYGRLSGQDLEQLQAGARVEVDENKRNPMDFVLWKMSKPGEPTWDSPWGPGRPGWHIECSAMNSKHLGLHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNTWMHTGMVMVDREKMSKSLGNFFTIRDVLAHYDAQTVRYFLLSGHYRSQLNYSEDNLKQARASLERMYTALKGLDLTVEAAGADEFVSRFMAAMDDDFNTPEAYSVLFDMVREINRLKTSDMAAASQLGVALKELAEVLGILSSTPEAFLQGEGNADEVAEIEALIVERNRARAEKDWPAADVARDRLNALGVVLEDGPEGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1043_SYNAS
Sequence: MSKNYVYILECSDKTLYTGWTVNIEKRLQEHNSGKYGAKYTKSRRPVKLVHLEMVDSLSGVLKREAQIKKMSRAEKLQLIKQNPERM
What are the official names of this protein?
UPF0213 protein SYNAS_10430.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: DNAK_MESHJ
Sequence: MAKEIILGIDLGTTNSVVAIIENQKPVVLENPNGKTTTPSVVAFKNNEEIVGDAAKRQLETNPEAIASIKRLMGTDKTVRANERDYKPEEISAKILAYLKEYAEKKIGHKVTKAVITVPAYFDNAQREATKNAGKIAGLQVERIINEPTAAALAFGLDKTEKEMKVLVYDLGGGTFDVSVLELSGGTFEVLSTSGDNHLGGDDWDNEIVNWLVKKIKEEYDFDPKSDKMALTRLKEEAEKTKINLSNQSVSTVSLPFLGMGKNGPINVELELKRSEFEKMTAHLIDRTRKPIVDALKQAKIEASDLDEVLLVGGSTRMPAVQSMIEHTLNKKPNRSINPDEVVAIGAAIQGGVLAGEISDVLLLDVTPLTLGIETLGGIATPLIPRNTTIPVTKSQIFSTAEDNQTEVTISVVQGERQLAADNKMLGRFNLSGIEAAPRGLPQIEVSFSIDVNGITTVSAKDKKTGKEQTITIKNTSTLSEEEINKMIQEAEENREADALKKDKIETTVRAEGLINQLEKSITDQGEKIDPKQKELLEKQIQELKDLLKEEKTDELKLKLDQIEAAAQSFAQATAQQANTSESDPKADDSNTIDAEIKQD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FTSA_ECO57
Sequence: MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKRVTASVGSWIKRLNSWLRKEF
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: KTHY_BURPS
Sequence: MARGKFITFEGIDGAGKTTHLQWFCDRLQERLGPTGRHVVVTREPGGTQLGETLREILLNQPMDLETEALLMFAGRREHLALVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVQPQVASARRGAVRMPDKFESESDAFFARTRAEYLRRAHEAPHRFAIVDSSESIPQIRRQLEGVLAAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YL295_MIMIV
Sequence: MCLPILVVMDSIINIDRVQIFIFDCINFLINDISLCYKIGIMNFLSPIFSTEIKSSEIKSNLMELDLSENYEQIIHNFVQYYRIINLFGVSYSEKYYNEQIHGFPNHYSIHLSGNISGKYRLDNYKSFLSKFNELGIKNIHYNNTNFYYQLINPKCISLVMFGSVYHQNKLCNIISVINLRVIHNIPKIINHMVIIT
What are the official names of this protein?
Uncharacterized protein L295.
Protein: PPAC_DICDI
Sequence: MSADSKNQKKVLFVCLGNICRSTMAEIVLRGLVHSRGILDDFQIDSAGTSSYHIGDTPDPRTVQSCNQNMGRAISEESLKHFKSIPLHRARQFTDEDFSKFDYIFAMDESNLSNIKKVLKHSTTKDNHIATIKRLGEYHTHKKINVEDPYYGDMSNFNICFNHVHDCLVNFLKEIESLN
What is the function of this protein?
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
What are the official names of this protein?
Low molecular weight phosphotyrosine protein phosphatase, LMW-PTP, LMW-PTPase, Low molecular weight cytosolic acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_ECOSE
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHSTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ENO_ACIET
Sequence: MSAIVDIVGREVLDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKARYLGKGVLKAVEHINTEISEAVLGLDASEQAFLDKTLIDLDGTDNKSRLGANAMLAVSMAVARAAAEESGLPLYRYLGGMGGMQLPVPMMNVINGGAHANNSLDLQEFMIIPVGAPSFREAVRWGAEVFHALKKIIHDKGMSTAVGDEGGFAPSVENHEAAIQLILQAIEAAGYTAGEQIALGLDCAASEFYKDGQYVLEGEGGLRLTAQQWTDMLATWCDKYPIISIEDGMAEGDWDGWKTLTERLGQNVQLVGDDLFVTNTKILKEGIDKRIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNAGQIKTGSLSRSDRIAKYNQLLRIEEDLGDIAFYPGRAAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YGFZ_ECO8A
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVE2
Sequence: MAARLCCQLDPARDVLCLRPVSAESCGRSVSGSLGDLSSPSPSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQILPKVLHKRTLGLSAMSTTDLEAYFKACLFKDWEELGEEIRLKIFVLGGCRHKLVCAPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: NADD_PHOV8
Sequence: MEKSKIKTGIFGGSFNPIHMGHLALANYLCEYNGLDEIWFLVSPHNPLKQQTDLWDDNLRLELVKLAIADYPKFRASDFEFHLSRPSYTIHTLDALHKAYPNREFTLIIGADNWLLFPRWYKAEEILKNHHVMIYPRPNFTIDPTTLPPSVQLADTPLLEVSSTFIRQALAEGRDIRYFLHPAVYERLKK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y3691_SHEFN
Sequence: MKQSIVHIALVVNDYDEAIDFYVNKLKFDLIEDTYQAEQDKRWVVVSPPGSNGVSLLLARASKPEQHDFIGNQAGGRVFLFLNTDDFWRDYNRMQLDGIKFVRPPQEQDYGTVAVFEDLYGNLWDLLQLNDKQPI
What are the official names of this protein?
Uncharacterized protein Sfri_3691.
What is the protein family that this protein belongs to?
To B.subtilis YwkD.
Protein: RR16_STAPU
Sequence: MVKLRLKRYGRKQQPTYRIIAIDVRCRRDGKALKEVGFYDPLKDKTQLNVPAILTLLQHGAQPTDTVSHILQKAGVFEK
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSAD_LACDA
Sequence: MKEKKDIRILAFESSCDETSTAVVKNGSEIESLVVATQIKSHARFGGVVPEVASRHHIEVITQITREALEEAKVSWEDLDAIAVTHGPGLVGALLIGINAAKAASMATGLPLIGVDHIMGHISAAQLVEPVEYPALALQVSGGHTEIALLKDPTHFEIVGDTRDDAAGEAYDKIGRVLGVNYPAGKTIDQWAHQGKDTFGFPRAMIDEDNYDFSFSGLKSAFINTCHHADQIGEKLDKYDLAASFQAAVVDVLAEKTVRAIRQYQPKTFIMGGGVAANLGLRERMNKEIAALEKAPKVILPPLKLCGDNAAMIGAAAYNQYLAGNFADLTLDADPSMELPYAEDYK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.