PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_SHISS
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CDKG2_ORYSI
Sequence: MAAGRHGGYRDYEARERELDAEASRRSKEQQHHHHPSGRHQRGDSDPRCEADRRRDGGRSRGGRELSNGYGHRRSPPPRSRLSARLGDREPGEVLSGSASDDSGGRPHRARENGVSSSSRDGESVVAASASSPSKKRKFSPIIWDRDSPKPMHSDVAKGKKAVDSVPTELPLPPPPPLPPQDHIPERLAVEKSPMDVEPAVASESPEQLQEHAESRVMEEEEEYSTMRNISTSRWAGANDDEEEGAPHRKKKSASPADSAELGQRKKALSPELGEVVASDISGGRTMSRSSDSGRLGADENEDLEVDKDDYMDVDRDDDGNSDIANHQSGMDSEYEVRRSETPEPVKPPHRCINMLQGCRSVDEFERLNKINEGTYGVVYRARDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQLVVTLWYRAPELLLGTKEYSTAIDMWSVGCIMAELLAKEPLFNGKTEFEQLDKIFRTLGTPNEKIWPGYAKLPGVKVNFVKQPYNRLRDKFPAASFSGRPILSEAGFDLLNNLLTYDPEKRLSADAALQHEWFREVPLPKSKDFMPTFPALNELDRRTKRYLKSPDPLEEQRLKELQGNIGNRGLFG
What are the official names of this protein?
Cyclin-dependent kinase G-2, CDKG;2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: RL20_MYCSK
Sequence: MARVKRAVNAQKKRRTVLKASKGYRGQRSRLYRKAKEQQLHSLTYAYRDRRARKGEFRKLWISRINAAARANDITYNRLIQGLKAAGVEVDRKNLAEIAVSDAAAFTALVEVAKAALPEDVNAPSGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS18_HAES1
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ESR3_MICUN
Sequence: MAVASSPEKDQPLLQLQKVDSSRVGGQVLSPTLSSSLETSQPICITSPYTDLGHDFPTIPFYSPTIFSYAGPSISDCTSVHQSLNPSLFWPSRGHMGSPIPLHHSQHGQPIQSPWVEISPLDNVLKTKQDGASLPLAVVPVRHKSARRRSQESEEAVVTSGGKTDLHYCAVCHDYASGYHYGVWSCEGCKAFFKRSIQRDNEYICPATNECTIDKNRRKSCQACRLRKCYEVGMTKCGMRKERGNYRSPQMRRMTRLTSQGRTDSSSVLTGSAVVSLNAPQPSALTSEQLIERLMEAEPPEIYLMKDMKKPLTEAKVMMSLTNLADKELVHMITWAKKIPGFVELGLLDQVHLLECCWLEVLMVGLMWRSVDHPGKLVFSPDLSLSREEGSCVQGFAEIFDMLLAATSRVRELKLQREEYVCLKAMILLNSNMCLSSSESSSKLLRLLDAVTDALVSAIGKTVLSFRQQYTRLAHLLMLLSHIRHVSNKGMDHLHCMKMKNMVPLYDLLLEMLDAHIMHSSRLPRRSPEQEPEDQADAPAPPHSSGSGPSYTWTPSSSEGAGEPQ
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor gamma, ER-gamma, Nuclear receptor subfamily 3 group A member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PALB_KLULA
Sequence: MPRGAQAMLEKQADSVWNQLYEICWNFYVKNVWDINTFKAIVDKIEKSDDKQLIRFLIWFNDARKRSNFNDKFQWMTSFLYGRRYPPLGDDLVVKEPWNDLQQLDSIIKYGNEPIDLVKMQPDFTTEERIVQNRRVNNCSLICSLTNAREENQIKSYSVHNVFNVILHFNGSNRLVSVLRDSNFPKCSKDGAALTLFSHNIEDMLIELAYFEIKNNRNYAYGGSNTATDTYLLTGWIPEILNLGDVSFSEIRKCYQFNAMLALGTDSVKGKEVTENHDFVVTSVNWKKEQFTILNPHGTENPTVYTWDDLIKEFKWLYVNWDPYSKYTQRVKLHDRYPDKFNAYPTWTQKPLMCIENKSNSIQNCHLYLERHLLDDSILESNLTIGEIPRSGFTAVSAEGNNSGFCNMQLRLNPHETRLIFYHSDKKCNLTFHLLSNSGLVSMSKCKSDILTAESSWNITNNQWTIGTSEYFKSPVFKLKSDGFDDTYLDFELVSQLPAKVNFQIFESDDYALQRPIFKNDTYSPQIFSKHGVRLLKGREYFIVCSIAHHITSPFIFTLRNPETKQSKFELSPYSLGFGGLRYNEVLRCKTRITISVSNFTRLFVLLFTSASKTNGRLTLRLYEKETEEILFEQIETRYDLSVKPFPIPNIELKPASYVLEIFYNADVVICNLGTSHRAIFESDL
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
Calpain-like protease palB/RIM13, Cysteine protease RIM13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
Protein: ATG22_CRYNJ
Sequence: MPPPHVRAWYSYAFAAEVFSSYPSGNIPANHFGTCDGKALQSSDPRGMDRYSFVQSSSMYVKSIAVACQAICIISIGPLADIAYWRKRLLLTFAYSGSLSGILFLLFPPLPYAWTPIMAAILNIVGNATYSTSIVCSNAFLPGLAKEDVDVQKAWEEATSEGLQDGLRDVHEDTDEENTGSVSREDEATHLLPDRLIPAVCAISTQDLALSDPLAKLIEPSNAKKHYESRLSLTTSRLSSTGTAIGFFSGVSVLTLLLIPVTALGGSTFSMRLAIGLSGVWWALFTVPTCIGLPGGAPGHGSDFSASQVKKAWVKIGKMVAPKQIHQLPNLYIFLLAWIFLSDGFHTTTYAAILYASSVLSMSAPKIILVGILVQLAAVVSSVLVPRVQRRLSTTSSKPVTNYKVLLAGVVAAAFIPVYTCAGLVLPFGGLRSEGEMYVLAVWFGLVFGPFLSYSRAVYAELIPPGHESTFFSLFAFTDKSASFIGPAAVGLISDLTGNIRYGFLFLLVMLVVPIPVLGRVAVERGRREAVEWAERSRKEMSDERV
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: ORF11_PENRF
Sequence: MDALEAPELLLLPHLSALTPKTGFLIGLALAITAYCYYRHTQHPLYKFPGPRSAAWSNVLYCYYYIQGRQPFKLLELHNQYGSVVRTAPNDLSFNTAGAFRDIYNFRPGHETFIKSDWYDGGVFADKAHSIVSEREPGKHGHMRKYLSHAFSDKSLKAQEPLIDEVVNEFVSQLDVFGSKKGGIDIVVWFNLATFDIIGSLAFGESFGGVKSGEVHPWISRIITAIGQSALADAFKRFPKFATTFKWLFPKAIEKMLEDTAGHENYTISLIDKRLSNPSTRPDFLTRMLENRPEDLTDVQIAAHASDFVIAGSETTATTLSCIVYYLTKNPSVYQKATQEIRDRFERFEDINSTAASQLKYLHALALEAMRIYPPLPLALPRVVPKGGDTIDGHFVAEGTIVSVNPVAACLSTKNFDAPLEFRPERWLESDLVDDHEASQPFSMGPRACLGRNLAWIELSLLLSKMLWVYDIELLNTEVD
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin (PubMed:24239699, PubMed:27921136).  The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:8440737, PubMed:15186158, PubMed:24239699).  Following the formation of aristolochene, the non-oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B, via 7-epi-neopetasone (PubMed:24239699, PubMed:26274339).  This conversion appears to involve three enzymes, a hydroxysterol oxidase-like enzyme, the quinone-oxidase prx3 that forms the quinone-type-structure in the bicyclic nucleus of aristolochene with the C8-oxo group and the C-3 hydroxyl group, and the P450 monooxygenase ORF6 that introduces the epoxide at the double bond between carbons 1 and 2 (PubMed:24239699, PubMed:27921136).  No monoxy or dioxy-intermediates have been reported to be released to the broth, so these three early oxidative reactions may be coupled together (PubMed:24239699).  Eremofortin B is further oxidized by another P450 monooxygenase, that introduces a second epoxide between carbons 7 and 11 prior to acetylation to eremofortin A by the acetyltransferase ORF8 (PubMed:16345540, PubMed:24239699, PubMed:27921136).  The second epoxidation may be performed by a second P450 monooxygenase (PubMed:24239699).  After the acetylation step, eremofortin A is converted to eremofortin C and then to PR-toxin (PubMed:24239699).  First the conversion of eremofortin A to eremofortin C proceeds by oxidation of the side chain of the molecule at C-12 and is catalyzed by the short-chain oxidoreductase prx1 (PubMed:16345540, PubMed:24239699).  The cytochrome P450 monooxygenase ORF6 is probably also involved in this step (PubMed:27921136).  The primary alcohol formed at C-12 is finally oxidized by the short-chain alcohol dehydrogenase prx4 that forms PR-toxin (PubMed:16345540, PubMed:24239699).
What are the official names of this protein?
Cytochrome P450 monooxygenase ORF11, PR-toxin biosynthesis cluster protein 11.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EDL14_ARATH
Sequence: MAEESLLPSHTEDVSASPNKSSSLLSEISNASTRPFVLAFTVGSCGALSFGCIVGYTAPTQSSIMKDLNLSIADFSFFGSILTVGLILGALICGKLADLVGRVYTIWITNILVLIGWLAIAFAKDVRLLDLGRLLQGISVGISSYLGPIYISELAPRNLRGAASSLMQLFVGVGLSAFYALGTAVAWRSLAILGSIPSLVVLPLLFFIPESPRWLAKVGREKEVEGVLLSLRGAKSDVSDEAATILEYTKHVEQQDIDSRGFFKLFQRKYALPLTIGVVLISMPQLGGLNGYTFYTDTIFTSTGVSSDIGFILTSIVQMTGGVLGVLLVDISGRRSLLLFSQAGMFLGCLATAISFFLQKNNCWETGTPIMALISVMVYFGSYGLGMGPIPWIIASEIYPVDVKGAAGTVCNLVTSISSWLVTYSFNFLLQWSSTGTFMMFATVMGLGFVFTAKLVPETKGKSLEEIQSAFTDSTSEDSTIF
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Sugar transporter ERD6-like 14.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RR3_SACOF
Sequence: MGQKINPLGFRLGTTQNHHSFWFAQPKNYSEGLQEDKKIRNCIKNYIQKNRKKGSNRKMESDSSSEVITHIEIQKEIDTIHVIIHIGFPNLLKKKGAIEELEKDLQKEVNSVNQRLNIAIEKVKEPYRQPNILAEYIAFQLKNRVSFRKAMKKAIELTKKADIKGIKIQIAGRLAGKEIARAECIKKGRLPLQTIRAKIDYCCYPIRTIYGVLGVKIWIFVEEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMN_SHESH
Sequence: MSEKKINLLDLDRKGLRALFTEMGEKPFRADQLMKWIYHFGETDFDAMNNINKVLRAKLSARCEVVAPEISSYQKSADGTIKFAINVGQGQEVETVYIPEEDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIIGQVWRVANFIGFQKETGERPITNVVMMGMGEPLLNLANVIPAMDIMLDDFGFSLSKRRVTVSTSGVVPALDKLGDALDVALAVSIHAPNDELRDVLVPVNKKYPLEEFLAGIRRYIAKSNANRGRVTVEYVMLDHINDSTDQAHELAKLMKDTPCKINLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQDSQISVTIN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MYCSS
Sequence: MANIKSQEKRIRTNERRRLRNQSVKSSLRTAVRGFREALDAGDKDKAAELLVATSRKLDKAASKGVIHKNQAANKKSALSVALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: Y264_METEX
Sequence: MSDIVSISSARPRLLVSVRGPDEALTALRAGADLIDAKDPERGALGALPPETVRAIVAGVGGRAVTSAVAGDGTGREIAAAIATIAATGVDFIKIAVGGADDAALAEAAAQAPGRVIGVLFAEDDVAEDGPARLAAAGFVGAMIDTRGKSGTTLTSLMAAPQLAAFVAGCRTHGLMSGLAGSLGLGDIPVLARLDPDYLGFRGGLCRASDRRQALDGARVAQAVEAMRAGPRADAA
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
Putative (5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: TIG_NOSP7
Sequence: MKVTQEKLPASQIGLEIEITPEITKQTYEQVIKNLASTANIPGFRRGKVPRPILLQRLGTTRIKAAALEELIQDGIEQAVKQEAIPAIGQPQLRSSFEDLINNYEPGKPLTILAAVDVEPEVNLVQYTDLLFQAEEVKYDPEQVDSSLEKERQELATLIPVEGRSAQIGDIAVVDFKGSFAKAEGEDETAELEPIPGAEATDFQVELQEDKFIPGFISGIVGMNPEETREIAAQFPDPYANEDLAGKAATFIVTLKELKEKELPEINDDFAQEISDFETLEELRASLVERYQKEADDKTKTNKQEALLTELLKHVEVDLPLTLVEQEVDAMLTQTAMRLSQQGLDVRKLFTQDIIPQLRERSRTEAIERIKRSLSLREVGKRESIEVTPEEIGVRVKELLEQYPEEKEVDEDRLRSIVENELLTEKTIDWLLEHSSVELVPEGSLSPAEETEAAESDADADVSQTEQENSEPSTTEVTEG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EF1B_STAMF
Sequence: MAKVLVLLKVLPEDINIDLEELKEKIRKALPEGYEIKGYDIEPIAFGLKALRLYIFMPEETEGGTEPLENTVMNVEGVSQVEVEAVHRIT
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: RL34_SYNS3
Sequence: MTKRTFGGTSRKRKRVSGFRVRMRSHTGRRVIRTRRKRGRSRLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL17_RHOPA
Sequence: MKHGKVHRKLNRTAEHRKAMFANMCAALIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLDKRRQAIAEMRDIEQVKKLFDVLAPRYKDRNGGYTRIIKAGFRYGDNAAMAVIEFVDRDEDAKGRDSGPTQDNSEAEAA
What are the official names of this protein?
50S ribosomal protein L17, RRP-L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CREA_BACB0
Sequence: MQQITDLERTKILQNGGEKVKPTFSKEEMTRRNTRLREYMAKAGIDAVMFTSYHNINYYSDFLYTSFNRSYALVVTQDKHVTVSANIDAGMPWRRSFDENIVYTDWKRDNFLYAVKKVLNEGGFSSGRLGVENDHMTLDLRRQVQDALPNTELVDVSQAVMGHRMFKSDEEIDLIKNGARIADIGGAAVVEAIREGVPEYEVALHGTEAMVREIARTYPHAELRDTWIWFQSGINTDGAHNWATSRKLQRGDILSLNCFPMIAGYYTALERTLFLEEVSDRHLELWEINCKVHRRGLELIKPGARCMDIAAELNEIYREHDLLANRTFGYGHSFGVLSHYYGREAGLELREDIETVLEPGMVVSMEPMIMIPEGEPGAGGYREHDILVISENGTENITKFPFGPEHNIIKK
What are the official names of this protein?
Creatinase, Creatine amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. Creatinase subfamily.
Protein: SAM10_MOUSE
Sequence: MFTELRSKLSPPRARAGAVRPGFGERPDVDASAHFSFCQTLLEHTVSAENIPCHLPRTPGTSLTWHDSRSQRASSSRPIKLLQQPGSEIPQARLYSDHYGLYHTSPSLGGLTRPVVLWSQQDVCKWLKKHCPHNYLVYVEAFSQHAITGRALLRLNADKLQRMGLTQEAQRQEVLQQVLHLQVREEGRSLKLLSQASFGNMS
What are the official names of this protein?
Sterile alpha motif domain-containing protein 10, SAM domain-containing protein 10.
Protein: ICIC_HORVU
Sequence: YPEPTEGSIGASGAKTSWPEVVGMSAEKAKEIILRDKPNAQIEVIPVDAMVPLNFNPNRVFVLVHKATTVAZVSRVG
What is the function of this protein?
Inhibits both subtilisin and chymotrypsin.
What are the official names of this protein?
Subtilisin-chymotrypsin inhibitor CI-1C.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: GRK1_MOUSE
Sequence: MDFGSLETVVANSAFIAARGSFDGSSTPSSRDKKYLAKLRLPPLSKCEGLRDNLSLEFESLCSEQPIGKRLFQQFLKTDERHVPALELWKDIEDYDTADDDLRPQKAQAILAEYLDPQGTLFCNFLDQGMVTRVKEGPTGSQDGLFQPLLQATMEHLSQAPFQEYLESLYFLRFLQWKWLEAQPIGEDWFLDFRVLGKGGFGEVSACQMKATGKMYACKKLNKKRLKKKKGYQGAIVEKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEKFSQASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDSRTVYAKNIQDVGAFSTVKGVVFDKADTEFFQEFASGNCSIPWQEEMIETGLFGDLNVWRADGQMPDDMKGITTEEAAPTAKSGMCLIS
What is the function of this protein?
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed:10097103, PubMed:10704496, PubMed:26427409).  This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (PubMed:10097103, PubMed:10704496).  May play a role in the maintenance of the outer nuclear layer in the retina (PubMed:26427409).
What are the official names of this protein?
Rhodopsin kinase GRK1, RK, G protein-coupled receptor kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Cell projection, cilium, photoreceptor outer segment. Note=Subcellular location is not affected by light or dark conditions.
Protein: Y1236_METTH
Sequence: MSEGDSMKMVIRPRHMISLGGYIVELEFPYRNLIVVNPTDEHIKIEVPVFDEEWIEEHRKLGLKIVPVGDDDNYLSLWRREKALLEASD
What are the official names of this protein?
Uncharacterized protein MTH_1236.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1436.
Protein: DAPD_BARBK
Sequence: MTDLIQLKMIIEKAFNNHDSLNTATKGEIRDSVEYTLNLLDKGEIRVAERQENGQWHVHEWLKKAVLMSFRLNPMHIISGGANESFWWDKIPSKFSGWQETDFKKANFRSVPGAIVRHSAYIASNVILMPSFVNLGAYVDEETMIDTWATVGSCAQIGKHVHLSGGVGIGGVLEPLQASPTIIEDHCFIGARSEVVEGCIIREGSVLGMGVFIGKSTKIIDRSTGEVFIGEVPAYSVVVPGSLPGKPLPNGEAGPNLYCAVIVKRVDQKTREKTSINDLLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_STRPB
Sequence: MKIVISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RS3_CAMJE
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKANLVENIGEDYKIRAFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDNLRKELQDLIGKDVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEARTTYGNIGVKVWIFKGEVLHKGMQPEKTEESAPAKKPRRTRRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MDH_STAES
Sequence: MLMVNRRKISIIGAGHTGGTLAFILAQKELGDIVLIERQQSEGMAKGKALDILESGPIWGFDTSVHGSVNIEDIKDSDIVVMTAGIPRKSGMTREELVQTNEQIVRETALQIATYAPHSIIIVLTNPVDVMTYTAFKASGFPKERIIGQSGILDAARYRTFIAQELNVSVKDVNGFVLGGHGDTMLPLINNTHINGIPVKHLISEEKIDQIVERTRKGGAEIVALLGQGSAYYAPATAIYETIDAIFNDRKRLLPSIAYLEGEYGCSDICFGVPTIIGYQGIEKIIEVDMNNDEYQQLQHSAQAVSEVKNSLKFK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: IF4G3_MOUSE
Sequence: MNSQPQARSPFFQRPQIQPPRAAIPNSSPSIRPGVQTPTAVYQANQHIMMVNHLPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFANAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPASTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSKEEDAPPVPSPTSCTAASGPSLTDNSDICKKPCSVAPHDSQLISSTILINEMNGVGEKLSAKENTVGMLRQEVLPLTLELEILEHPQEELKVECTPTPIAPSMLPAFSPAPPTPPTSPPCPPVVLSAAIARSPAVATEVQRVADEGESLRTCLSKDAKEMQDKAESESDGQAEETADPQSLHSGRSPAPVQTATTAPKSWKKTKEQTRTPDEVLEAEAEPKAEEELAVDSVLEPEQEKMSQGFPSERDPSALKRGKAEEGNGEEAEPVRNGAESASEGEGGDGNSGSADSSADGLTFPFKAESWKPADTEGKKQYDREFLLDIQFMPACIQKPEGLPPISDVVLDKINQPRLSMRTLDPRILPRGPDFTPAFADFPRQTPGGRGVPLLNVGPRRSQPGQRREPRKIITVSVKEDVHLRKAENAWKPSQKRDSHADDPESIKTQELFRKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASESDALRSSASSLNRFSPLQPPAPSGSPSATPLEFDSRRALTSRGSMGREKSDKPIPAGTARPNTFLRGSSKDLLDNQSQEEQRREMLETVKQLTGGLDAERASTEADRSKTRELAKSEMCAVPAPDKPALSEEEVERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKKVGALWREADLSWKDFLPEGEDVHHFLLEQKLDFTESEGPCSSEALSKKELSAEELSQRLEKLIMEEKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQAGKGVALKSVTAFFTWLREAEEESEDN
What is the function of this protein?
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome (PubMed:35951695).  Functional homolog of EIF4G1 (PubMed:35951695).
What are the official names of this protein?
Eukaryotic translation initiation factor 4 gamma 3, eIF-4-gamma 3, eIF-4G 3, eIF4G 3, eIF-4-gamma II, eIF4GII.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: SYL_SALDC
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.