PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_CAMJE
Sequence: MNPSEIKKLRTESILKELIPEALANLDDENLKNLCVVDVECKKGRYDAFVYLDKMFFNVHEQEKILSSLKKASRALQNYCMSEQGWYRCPNFHFKFDDRLEYQNHMDALFEKIKKDKNES
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_RICPU
Sequence: MAVKIRLARGGAKKRPFYRVVVANATAPRDGDFLEKVGTYDPMLASDNSERVVLKKDRIEYWLGTGAKPTERVAKFIEQAGVTLPEKVKKEMEVKAKNRKARLSKKEAKEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y8734_DICDI
Sequence: MTIINNISTFGSKNNMANATQKIDFQNTTNQLNTSNNISNSLQSSAKINTTCDNSCSQNDIIIGGYKLPKSSELPYDCTIC
What are the official names of this protein?
Uncharacterized protein DDB_G0272188.
Protein: ACCD_STAAB
Sequence: MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_VESOH
Sequence: MKVLLANPRGFCAGVDRAIEIVECALKLHGAPVYVRHEVVHNKFVVDGLKNKGAVFVEDIADVPNNQVVIFSAHGVSIAVRRQTHNIGAIIYDATCPLVTKVHKEVARKQKQNYQVILIGHKGHPEVEGTLGQSSESNCVQLVETIEDVERLNLSKNMSFSYTTQTTLSIDDTQSIIDYLKLRIPTIDMPKKDDICYATQNRQDAVKILMQFSSVLLILGSSNSSNSNRLREIAEKIGIPAYLIDGIDNIDELWFKGVDTIGVTAGASAPEVLVQEVVHYLRDKGATKVIEVGGVKENIHFPVPKELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PA_I72A4
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: PD2R_HUMAN
Sequence: MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
What is the function of this protein?
Receptor for prostaglandin D2 (PGD2).  The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.  A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
What are the official names of this protein?
Prostaglandin D2 receptor, PGD receptor, PGD2 receptor, Prostanoid DP receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TYSY_PARD8
Sequence: MKQYLELLNRVLTEGVRKEDRTGTGTISVFGHQMRFNLEEGFPLLTTKKLHLKSIIYELLWFLNGDTNVKYLQDHGVRIWNEWADADGSLGHIYGYQWRSWPDYKGGSIDQITEAVETIKHNPDSRRIIVSAWNVADLDNMNLPPCHAFFQFYVANGRLSLQLYQRSADIFLGVPFNIASYALLLQMMAQATGLKAGDFVHTLGDAHIYSNHLEQVKLQLTREPRALPRMEINPDVKSIFDFKFEDFNLTGYDPHPHIKGEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YORI_BACSU
Sequence: MLQDKQAIIQVLGSILKDPTILSESNKYKITSDDFPSRFHSILFFAMSNLFHQGTEVLNDVEIDGYLKDYDIQYKIFHDNKGLEYIEKIQELAVVENFDYHYKRLKKFSLLREMDGLGFDIKEIYDESLIDPKEQEKMQEQFDKKSIDEILTAYEMKIVDIKEKFRTSSESVGIQGGEGINELLDSFEESPDIGVPLNSEMLTSIFRGSRKKKFYLRSSITGGGKTRNMVADACRLSATELYDPKKKEWVSNPWSESSTVISTEMMAEELQSLALAYISSVEEKKILRNTINEKEKQLVRKAAKVLQESNIWFEHLPDFNIQEIERTIEKNVIKNNVEYVYFDYIHSSVTIFSEMSKKSGVNLREDQILLLMSDKLKGLCNKYDVYMMSATQLNGDWKEAWLKGQVIDASYLRGSKAIADKTDAAMIILPLSKKEKDAIDPILKEGFYPEPNFVTHVFKNRGNEYDKVKVFSHINMGNMRIKDCFTTNLDNELITVEKLNIKAG
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YorI.
Protein: RECD_BUCAI
Sequence: MLILLKKAVKLKIIRPIDFYFSQFIAQKNNIVMLVAACVSYESSRGYISLPIKYFEKHYFFSSSNEVFIKKILTLLEKKINWPVELLKHASIGNGGTSTPLVLHKKKIYLYKMWKSESNIFNYLYTKNKKNKINQKKCSKILENLFPQKNMSFQKIAVALTLINNITFIIGGPGTGKTTTILKIIIALIKSSKKSIKIQLSAPTGKATTHLNEILKNNIFDLYFSEKEKCSLPSTATTIHQLLGIQKISQKSFFNKSNCLDLDVLIIDEISMVDILMMEKILSSISKNTKLIFIGDHNQLGPIESGSILRKICYYANDGYSFKSMISIEKLTQYKLCKKINKKTTNFISDNICVLNKNYRFNKNSGIYTLSNAIFKKKTRIIESLFDNSIKNIFFYETNSSEQYKKMIKNICLNYEDFWEKIYKKATMKEIIESFQNYQVLCILHDGLFGVNIINKKLEENMYKKNIIKYFYIDGEEWYIGKPIMIINNNRALNVSNGNIGITNINKNGILQVSFLKENNTINNIPVKILRNYKTAWAITVHKSQGSEFMNTALILPNFNSHILNKDTLYTGITRSRKILSIFSDKKIFLNTIFKNTNKILF
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity.  When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity.  Negatively regulates the RecA-loading ability of RecBCD.
What are the official names of this protein?
RecBCD enzyme subunit RecD, Exonuclease V subunit RecD, ExoV subunit RecD, Helicase/nuclease RecBCD subunit RecD.
What is the protein family that this protein belongs to?
Belongs to the RecD family.
Protein: CCA_PSEU2
Sequence: MQIYKVGGAVRDRLLGQPVTDIDWVVVGASTEDMLIKGYRPVGTDFPVFLHPLTNEEYALARTERKSGVGYGGFVFHASPEVTLEQDLIRRDLTINAMAEDKDGNLTDPYNGQKDLQARILRHVSPAFAEDPLRVLRVARFAARYAGYGFTIAPETLGLMRQLSASGELKALTAERSWKEISRALMEEQPQVFIQVLHDCGALKELMPEVEALFGVPQPAAHHPEIDTGVHVLSVLEQSARHKHPLTVRWACLLHDLGKGLTPEAEWPRHIAHEHTGLRLIKAVNERFRVPRDCQELALLVGQYHTHGHRALELKPSTLLELLQSFDVYRRPQRFEEFIAACEMDARGRHGFEQRSYPQADYLRGAAEAARAVSVQPLLEQGLKGKELGDALKNERLKALKTYKTSTV
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: APT_NITHX
Sequence: MTFEDDLQASVRTIPDYPKPGVMFRDITTLLGDARAFRRAVDQLVHPWAGSKIDKVAGIEARGFILGGAVAHQLSAGFVPIRKKGKLPHQTVRMAYALEYGTDEMEMHVDAIAKGERVILVDDLIATGGTAEGAVKLLRQIGADVVAACFIIDLPDLGGAAKLHAMDVPVRTLMAFGGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF78_NEPOL
Sequence: MALAQESVFSVLYHLKHDPVDYWFHNWVLHGPMLFRSIGSGIVNFCTFQWVGWLIHLPIVRPDALASLFHEYDLPSSIEAGATPIRGMLTISQTVPTTAGMDPFLLGIMNSPALVISISTTTILCLRWLSLDLRWAAILAFFGNFLSNWLVVVAVLFGLDDLVARWYFLTPFTYVGSVLFIWYLVYKWIKVGLNFDLTSKGPFGMNPEVWRGLKIGMTGFTLGLCEQTVLFHKLIQPLSPHQLDLLHGFTSGTVRDHIVMHGAYVIGLFVGGVFLGSVILSVLIPAVDTWSEKKLLTQARFSLLLIMMTGASLPYYGFDYLLTRFADFAPDGGWRESTIFKPSLNKHLVSKNIHRKFTIADSTRRDTARPWREARNLFPERRWLLKVGTKSKAKLSTLPILDFVTHWRGGEDFVYSIVNPADFYRDLTKDPLQGKGKTLDKAVWKFVGNFFYQWKDEDLSRRKFQEQVKGIVDYARYRMVVINDIHVKGLVTTEQGDIRGVVDQHADMKLLQLPEAFVNQRLVKPPFLKHDWVLTIPKMSEQAKEERLLLKRQKMPPELSIEQQKTFFDSNAQKLFGTPNHYGLPEALDSSLESEEENLDPEEDIDPEIVDPLSSEESKTIDTLKVDLRTLSKNAKWVPKSVIQKQAAEKAEEERKAEEEKLLAVRNAKKKGLTVPKTEPKKGLTKQRQANPLGTPSLFYDKLHKRAEWNNEDFPHWGYMYHQLWKHRAYSHFMFRRLLEVDVDSMLARQPSRNFVTDADYQRLQYHQVALSSYHRSLRDYETSLWNVLLEPRANFFLAPNPLWRWDADWKVGFRAKSLENYVYDQRFKGTHRVVQRLFLLDTQFNPWDKTGPQFRYDQLLPLEEQDKGDRSNLWHEEIPREVRENVGAYDPFESQRVPPMFDPVPFYIGWDPILRKSVLTTSRLPKGTARVKLVLPGTQTPKWLKFIVSLESSDS
What are the official names of this protein?
Uncharacterized membrane protein ycf78, RF1, ycf1.
What is the protein family that this protein belongs to?
Belongs to the ycf78 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: ELMO2_BOVIN
Sequence: MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDADSDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDRDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Acts in association with DOCK1 and CRK.  Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.  May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
What are the official names of this protein?
Engulfment and cell motility protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Membrane.
Protein: THII_MARN8
Sequence: MKLLIRPAPEVAIKSKPVRQQQMRQLRQNIRKLLARLDPEIRVDGSWDRVDVDVPDGRSLAGPVIDELVRIPGISTIQEIGVFPFVDLDDVGEKAVQAYAERLKGKTFAVRARRHGDHDFRSIDLERSVGAALLQGSDAKGVDLKSPDLEVRIEVKDDSYHIAHRRHEGLGGYPLGTVETVMTLISGGYDSSVAAYLMMRRGIRSHYLFFNLGGAAHEVGVRQVAHYLWERYGSSHNVKFISVPFEGVVAEIMRSVNHRHWGVVLKRMMLKAAAEIARDYNASGLVMGDAVAQVSSQTLTNLNVVDRASDEVVLRPLIAMDKQEIIRIAKDIGTEPFARNMPEYCGVISSKPVTRARLHRVEEDEANMDPAALADAIANRTDTMVSQLLDSTQTPEEVELIQTPSVDDVIIDVRHPSEEERSPLTLTNNDVLKIPFYELNQQVAELPGNRQYLLYCDRGTMSRMHAGHLKAEGHGNIKVYAPAV
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_NITEU
Sequence: MDNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLNYIDEIIGGLSEKTVIDVGCGGGILSESMAARGASVTGIDLSDKALKVAKLHLLESGNQVDYRKITVEALATERPRYYDVVTCMEMLEHVPDPASVIQSCARLVKSGGWVFFSTLNRNPKSYLYAIIGAEYILRLLPRGTHEYAKFIKPSELAHMARSAGLMESGIVGMTYNPITKVYALEADTSVNYIMAFRA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: KCY_ECODH
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_VIBVU
Sequence: MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLISLVKQVEKPLLGICLGMQLLGKVSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKGIEEGEYFYFVHSFAMPVGDYTIAECEYGNSFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFA_SHEPC
Sequence: MTEYLLLLISTVLVNNFVLVKFLGLCPFMGVSSKLESAIGMSMATTFVLTLASILSYLVNQYLLLPFDLSYLRTMSFILVIAVVVQFTEMVVQKTSAALHRALGIYLPLITTNCAVLGVALLNVNEKHDFIQSAIYGFGAAVGFSLVLILFSAMRERLAAADVPLPFKGGAIAMITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METXS_TERTT
Sequence: MPDSIPANSVGLVTPQLMQFDEPLALACGRTLDSYQLMVETYGTLNASRTNALLICHALSGHHHAAGYHSMDERKPGWWDAYIGPGKPLDTNKFFIVSLNNIGGCHGSTGPVTPNPSTGQPWGGDFPTLRVRDWVHSQARLADALGIQKWAAVVGGSLGGMQAMRWSLEYPDRVGHCVVIASAMKLSAQNIAFNHAAREAILTDPDFHDGNFLSHSTVPKRGLSTARVIAHLTYLSDDGMGQKFGRELRSGSFEQGTEEPVEFQIESYLRYQADSFSKVFDANTYVLMTRALDYFDLAREYGDDPVEAFKQAQCKYMVISFTSDWRFSPERSREIVNALIRADRDVVYGELESDFGHDAFLIPNQPRYWDLLTSYMSQIEVAD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STRAW
Sequence: MTTASSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEGVVLAVGPGRFEDGNRLPLDVTVGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_CHLT2
Sequence: MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRTLSGDGLADFRDYSSIDNTPEEKARGITINASHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKIDMISEEDAELVDLVEMELAELLEEKGYKGCPIIRGSALKALEGDAAYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLRDTKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCLPNSVKPHTRFKCAVYVLQKEEGGRHKPFFTGYRPQFFFRTTDVTGVVTLPEGVEMVMPGDNVEFEVQLISPVALEEGMRFAIREGGRTIGAGTISKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_STAAS
Sequence: MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQDIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: EFTU_ACICJ
Sequence: MAKAKFERTKPHCNIGTIGHVDHGKTSLTAAITKVLAESGGATFRAYDSIDAAPEERARGITIATAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFLNKMDMADPDLVELVEMEVRDLLSKYEFPGDDIPIIKGSALCALEDSNAELGREAILKLMEAVDSYIPQPERPKDKPFLMPVEDVFSISGRGTVVTGRVERGIIKVGDEVEIVGLKATVKTTVTGVEMFRKLLDQGEAGDNIGALLRGTKREDVERGQVLAAPGSITPHTNFSGSVYILNKEEGGRHTPFFTNYRPQFYFRTTDVTGVVTLPEGVEMVMPGDNVTVSVELIAPIAMDEGLRFAIREGGRTVGSGVVASITK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUT3_YEAST
Sequence: MVTDQGSRHSIQSKQPAYVNKQPQKRQQRSSVACLSCRKRHIKCPGGNPCQKCVTSNAICEYLEPSKKIVVSTKYLQQLQKDLNDKTEENNRLKALLLERPVSVRGKDNSDDDERHINNAPSSDTLEVSSAPAAPIFDLMSNSNTASDNDNDDDNSNRITNNRSYDHSLEKYYKKAISIFKQPANANGENGNGANGHEDDDEDDEEISTNFAQRSGRLIESHNGFHYFVGSSSMTLFGLEIQSLVTKYISVKNFRPLPINTKNKILNSNLNPAISSFINSNNYLFSSYNFLNPISTIVNLNSINDNLSPLMFKIILKSDTDGSSGQEEVIQFQLPSYNYTKLLIDCFINYNDGCFYFFNEGLVKCGINKLYLENKWLYYDNTKKALDNENDPILQAVWFCKILLILAVGEMYLGSINNEMLKNYSNQPKLPGSKFFQMGSKIFNCLFSSERLENVTKKGGIEVLLLYAFFLQVADYTLASYFYFGQALRTCLILGLHVDSQSDTLSRYEIEHHRRLWWTVYMFERMLSSKAGLPLSFTDYTISTALPADIDDETIEEKNSHYVFRKAELISNCVTIVKINAQILSKLYQRQPETNIIITLKVVIKQLLEWRNNLSDSLQVDFTQKDEDFKISRLSTNMFTEYFQGINLAVRPLLFHFASIQLKRFKTSNTFVNLQNYSATISSLLTCSLHASVNTIRSLWSLLQNSMLAMFSYMDREYLFTSSCTLLLFNTAFGIHEQTLYHLDHSLEIFTQMRNLGNIPAGLRRAQLLTLMANLDFHGIMNDLITKYNDILKFDSMNCENDNIVEDSNEPKRETEKCKPHKDGDRIDPSIIDCDKSNTNTNMIKNESISNIVSILPEGAKPTLTDYSNGNNDVNDINVNNSEPSTFFDIITASLENSYQTTLTEKGSQVMEKNMDQLDSVHNLNDDDLQQLLEDLGNIDHSDEKLWKEITDQAMWLGNTMDPTAAAGSEIDFTDYLGP
What is the function of this protein?
Positive activator of the proline utilization pathway.  Binds to the promoters of PUT1 and PUT2 genes.  Recognizes and binds to the DNA sequence 5'-CGG-N(10)-CCG-3'.
What are the official names of this protein?
Proline utilization trans-activator.
What are the subcellular locations of this protein?
Nucleus.