PharMolix/UniProtQA huggingface dataset:
Protein: VIAA_SALTI
Sequence: MLTLDTLNTMLAVSEEGMVEEMILALLASPQLVIFFEKFPRLKNAVTADLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILALLHRLHSPYAAQAKQLTESNSTFTPALHTLFLQRWRLSLVVQATTLNQQLLEEEREQLLSDVQERMTLSGQLEPTLAENDNAAGRLWDMSAGQLKRGDYQLIVKYGEFLAAQPELMQLAEQLGRSREAKSVPKKDAPMETFRTLVREPATVPEQVDGIQQGDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDVDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRVALADNRRCFIMLFSTDVVRYELSGPESIEQAIRFLSQRFRGGTDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVSKVGELQRLHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: DNAA_METPP
Sequence: MSADVWSQGCERLATELPEQQFNTWIRPLPAAELVDRGDTAVATLRVPNRFKLDWIRNQYAARIESVLSDLAGKPVRLDLQLAAREAPPRPSSDAPRSNGHPQAAGQWLGAPSSSNAGAYTQASAPTPTHRLNTALTFDTLVPGRANQMARTAALHVAGAPGVMYNPLFIYGGVGLGKTHLIHAVGNALLRDKPDARILYLHAEQFITDVVKNYQRKTFDELKAKYHSLDLLLIDDVQFFAGKERTQEEFFNAFEALLAKRAHIIMTSDTYPKGLADIDERLTSRFDAGLTVAIEPPELEMRVAILMKKSDVEGTPMPEDVAFFVAKNVRANVRELEGALRKVLAYARFSQKDINIALAREALKDLLSIQNRQVGVENIQKTVADFYKIKVADMYSKKRPASIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIGGERGKNTELNQQLHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSGN1_DANRE
Sequence: MAQIDVDVFTAKVLSHWDWSREDRSFGDSASSPESESFDSACSSPDARSSPTAGCEHAEQQKPKVKMSMRRRMKASEREKLRMRSLAEALHQLRDYLPPGYSRRGQPLTKIQTLKYTIQYIKELSGILEQQ
What is the function of this protein?
Involved in specifying the paraxial, but not dorsal, mesoderm.  May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
What are the official names of this protein?
Mesogenin-1, MesP-related bHLH factor, Paraxial mesoderm-specific expression and regulatory capacities, pMesogenin1, pMsgn1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU2C1_OENBI
Sequence: MIWHVQNENLILDSTRIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CHR4_SCHPO
Sequence: MDSASSMRNRSPLGVPEFSYSSQSVNNIRGIKSRNRSSIGHSITDPQVASRINAFYLSNVQSSIPFETDAIGPAYGIGDMIAPEMNDTQSLSASVTNMKKENFYSRPNVSSSSILLTIKRATSSQETKRDRPLPNIRNSAPSATRSHSTPCVAPGYLRTSNEAADVVFPHEEAHFSNHNPKPNNGSPLQKQVVADLPFPLPVSDEEQLDWIRANEDLVHSQDIDEALEWAEYVLRFTQSHLPYLQTYESENLHEINYLESMCENALYKIREFSELENAKAMYFDAYVYETGAFDVESDIQRAWDLYSSSANLGYTRSLYRLGVLLEDQGNLEEAVEYFEKGVSENDSACCWRLSLLILEGMLDGVGEYAHRHASGLELLERSADTADADVPSGLYSHALVNLHEHPGLVDLGSENIRVPIDEATALKSFAKAAFLGHSSAQLRMGAVYEFGKYGCPVVPRYSLFYYSAAAKRGETEADLAVAKWYLNGSDGIPVDEDLAFMHAERASMAGNANAQFLMGYLFDTRGNTEQATYWYNEAAKAGHSEAIERLALLENQIQEPEPENITSSQYPNQDVIKEIPVTASETSPPHAPAVSSTPVTSAPPVSQTKVTKVSVPKKTSKKFLIKHNKCIIS
What is the function of this protein?
Involved in septum formation.  Required for the proper localization of chs2 at the septum.
What are the official names of this protein?
Chitin synthase regulatory factor 4, Chs four homolog 3.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell tips and septum during vegetative growth.
Protein: NU4M_NEUCR
Sequence: MKKEFLMFLFALLIIPIIGIFIIWSTQFYSKMYQYPFYYMPYPFKKVVITEGANSCMLKDGSWSQVVLTDSDDMFIQNETAPKVVAFIISILNLMVSLLVYILFDFSNNQFQFIQEHYDLSFYDIYLGVDGISIYFVLLTTIIIPIALMSNWNSITNNVKSYLIIMLLLETLLLAVFLVLDILLFYIFFESILPPLFILIGLFGSSNKVRASFYIFLYTLLGSLFLLLSILTMSSIMGTTYFDALLKSNFDYTIQIFLFCGIFIAFAVKTPTIFLNNWLLKAHVESPLGGSIVLAGIVLKLSLYGIFRLILPLLPKASLNYTYIIFVIGVITIIYASFSTLRTTDIKELIAYSSVSHAAVYLIGVFSNTIQGIEGGILLGLAHGFTSPALFFIVGGVLYDRSGTRLIHYYKGIAQMAPLLSLLFFIFSLANCGVPLTLNFVGEFMSLYGVFERLPLLGLLASSSIVFSAAYSIFLFNRVAFGGSFSKFFENSIIDLTKREFYALIFLGVLVVFLGIYPSIILDGLHYNVSSLIYSYGCKFCLG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TRF6A_XENLA
Sequence: MSILNPRTSLEAGDSEDACCAAMASVCCINTKEDADSPSAGLPSGTTQNLDVEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACILKSLRNAGHKCPVDNEILMEKQLFPDNFAKREILSLRVKCPNLGCTDTMELRHLEHHLVQCQFASVECSQCQGSFLKLLLDKHMEHECGRRRTFCDNCGLAMAYEDKSGHELICPMAYVTCDYCQTNLIREQMPAHYSMDCTMAPIPCMYCEFGCREKMQRHNLAGHLQDFTQAHMRMMAQTLRSFSTTPTSHISDISFCDPNQFEPVPLSVAPAHPSHMPSQQDCSQETRNLRETVEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIHSLEDKVADMDAHRCNGVFIWRIKGFSGLQKSQEEEKPVVIHSPGFYTGDPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGDYDSLLPWPLQGTIRLSILDQSESTARQDQVEVMDTKPDLLAFQRPTAPRNPKGFGYVTFMHLNTLKQRQYVKNDTLLVRCSVNIHLDLTSPRREGFQPRSGEGTL
What is the function of this protein?
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2.  Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation.
What are the official names of this protein?
TNF receptor-associated factor 6-A, E3 ubiquitin-protein ligase TRAF6, RING-type E3 ubiquitin transferase TRAF6-A.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Nucleus. Lipid droplet.
Protein: CSRA_RHOBA
Sequence: MLVLSRKKNESIVINNDIKIVVVEIRGDKVRLGVEAPREVPVHRREVYDAIQRNNEAFDANAPADSNDVS
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_EHRCJ
Sequence: MNDNLKSSGIMLVISSPSGGGKTTISHLLIDELQNDLVRSVSVTTREPRDGEVNGKDYFFVTEHEFINLCNTDQMLEYAKVFGNYYGIPRKFVMDNITTGVSVLFSIDWQGAFKLIDIMREHVVSVFILPPSMEELRRRLYNRSGKSDIVKKRLGEAAFEIDHCYRYDYVIVNHDVEESVHQIKCIFTSERLRVQRRILLKQFIDNYIK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_LISMH
Sequence: MKKILIGGIRLYQKYISRFTPATCRFYPTCSAYGIEAIQTHGALKGSYLAIRRISKCHPFHKGGLDFVPPKKDKNADSEHSCKAHHHH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMG_FRAAA
Sequence: MGPPPAAPAAAAELFGPRLAAAERFTELLATAGVERGLIGPRETDRLWERHVINCGVLAEVVPEGADAVDVGSGAGLPGIPLALARPDVRVVLLEPMERRCRFLQEVVAAVGLEEQVSVLRGRAPDAGIGPEGRRFGVAVARAVAPLERLGAILLPMLQPGGVMLAMRGSRILEELQDARGSLGTQGWHPVDVVVCGEGRVDEPTRVLRAVRSSQLSRAEGRKGRGDGERHDGRQVRRTARDSRRSREVDRDQPTRGQSRST
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODAM_MOUSE
Sequence: MKIIILLGLIGASSSAPLISQRLLSASNSHELLLNLNNGQLLPLQFQGAFNSWIPPFPGFLQQQQAQVSGRPQFTLSTLESFAGLFPNQIPLSRQVGLAQGGQAGQPDLSQQQTPPQTQQSASPMSYVVPVKVPQDQTQMFQYYPVYMLLPWEQPQTVTSSPQHTGQQLFEEQIPFYNQFGFAPPQAEPGVPGGQQHLAFDSFVGTAPETPGMPVEGSLLYPQKEPISFKHDNAGVFMPTTSPKPSTDNFFTSGIDPTIAPEQKVKTDSLREP
What is the function of this protein?
Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth.  May be incorporated in the enamel matrix at the end of mineralization process.  Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK.  Plays a role in attachment of the junctional epithelium to the tooth surface.
What are the official names of this protein?
Odontogenic ameloblast-associated protein, Apin.
What is the protein family that this protein belongs to?
Belongs to the ODAM family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Nucleus.
Protein: RL14_SULNB
Sequence: MIQGFTRLNVADNSGAKEIMCIKVLGGSKRRYASVGDVIVASVKKALPTGKVKKGKVVKAVVVRTKKEIQRENGSLIRFDDNAAVIIDDKKEPIGTRIFGPVSRETRYAGFMKIVSLAPEVW
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ASSY_PROMA
Sequence: MGDFQKVVLAYSGGVDTSACIPYLKNEYGVEEIIAFAADLGQGEELEVVRKKALLAGAKESLVDDLIEPFIHDFAFPAIRANALYEGRYPLSTALARPLIASRLVELAREMEAGAVAHGCTGKGNDQVRFDLAISSLAPHLKILTPAREWSMSRQELISYGEKFGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDPFLAPREEVFQITSSIQESPDTPEEIEIQFEAGNPIAINGVTLDPVSIIKKANALAGRHGFGRIDMIENRVVGIKSREIYEAPGLMLLIKCHQEIESITLSADVLRTKVGIERQWADLVYQGFWFSPLKNALDAFIDRTQLDVNGSVKIQLFKGNATIQGRQSYSNSLYLPDIATYSAEDQYDHKSAEGFIYVWGLANRLWASINRDK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_OVICA
Sequence: MSLVYMNIMMAFTVSLTGLLMYRSHLMSSLLCLEGMMLSLFILATLMILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EIF3J_HUMAN
Sequence: MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:25849773, PubMed:27462815).  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j, Eukaryotic translation initiation factor 3 subunit 1, eIF-3-alpha, eIF3 p35.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_PSEA7
Sequence: MAAKEVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELKDKFENMGAQLVKDVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATVAIVAQLKELAKPCADTKAIAQVGTISANSDESIGQIIAEAMEKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFVNKPDTMAAELDSPLLLLVDKKISNIREMLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLEGATLEHLGNAKRVVINKENTTIIDGAGVQADIEARVLQIRKQIEETTSDYDREKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALQAIEGLKGDNEEQNVGIALLRRAVEAPLRQIVANAGDEPSVVVDKVKQGSGNYGFNAATGVYGDMIEMGILDPAKVTRSALQAAASIGGLMITTEAMVAEIVEDKPAMGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SALPA
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRIIDKKGIETVLSELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PUR5_EDWI9
Sequence: MTDKTALSYKDAGVDIDAGNALVDRIKGVVKETRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLQRHDSIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVISGIAAGCKQAGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSQIIDGSQVRPGDALIALGASGPHSNGYSLIRKILEVSGCDPRTTMLAGRPLADHLLAPTRIYVAACLDLIASHEVHALAHLTGGGFWENIPRVLPAGVKAVIDEGRWQWPAIFDWLQQAGNVSRHEMYRTFNCGVGMVIALPPAQVDSALARLSQRGEQAWLLGHIAEAQGDGPQVEILR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVP1_ECOLX
Sequence: MIIGYARKSTHLQDVTHQVDELTKAGCEQIYHEQISRGGSKRAKNGAPELENCLKALREGDTLVVWALDRLGGSLSQVITLLDDLKKRGITFIAIKDRIDTSAPVIGEIYTHLMAIFSNFERNRNIERTRSGLAAARARGRVGGRKPSLSEDDINEMKILLADPEMTVGAVAKRFNVSRMTIYRYTTKGNHSEKINDE
What is the function of this protein?
Cooperates with the mucAB genes in the DNA repair process.  Could be a resolvase-invertase protein.
What are the official names of this protein?
Protein uvp1.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: ECR_LUCCU
Sequence: MMKRRWSNNGGFAALKMLEESSSEVTSSSNGLVLSSDINMSPSSLDSPVYGDQEMWLCNDSASYNNSHQHSVITSLQGCTSSLPAQTTIIPLSALPNSNNASLNNQNQNYQNGNSMNTNLSVNTNNSVGGGGGGGGVPGMTSLNGLGGGGGSQVNNHNHSHNHLHHNSNSNHSNSSSHHTNGHMGIGGGGGGLSVNINGPNIVSNAQQLNSLQASQNGQVIHANIGIHSIISNGLNHHHHHHMNNSSMMHHTPRSESANSISSGRDDLSPSSSLNGFSTSDASDVKKIKKGPAPRLQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYCCKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKIQTSVCATEIKKEILDLMTCEPPSHPTCPLLPEDILAKCQARNIPPLSYNQLAVIYKLIWYQDGYEQPSEEDLKRIMSSPDENESQHDASFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHNSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMYSMKVDNVEYALLTAIVIFSDRPGLEEAELVEAIQSYYIDTLRIYILNRHCGDPMSLVFFAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHIQATQAEKAAQEAQATTSAISAAATSSSSINTSMATSSSSSLSPSAASTPNGGAVDYVGTDMSMSLVQSDNA
What is the function of this protein?
Receptor for ecdysone.  Binds to ecdysone response elements (ECRES) (By similarity).
What are the official names of this protein?
Ecdysone receptor, 20-hydroxy-ecdysone receptor, 20E receptor, EcRH, Ecdysteroid receptor, Nuclear receptor subfamily 1 group H member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYP_CLAM3
Sequence: MSTRLSKLFVRTLREDPVDAEVASHRLLVRAGYIRRQAPGIFAWLPLGLRVKNKVEAIVREEMERIGAQEVHFPALLPAEPYQATGRYDEYGPGMFRLEDRKRAPMVLAPTHEEFFALLVKDLYSSYKDLPLSIYQIQDKYRDEARPRAGILRGREFTMKDAYSFDHTDAGLAVSYQAQRDAYERIFQRLGLEYVIVAADAGAMGGSKSEEFLHPTPIGEDTFVRSPGGYAANVEAFTTLVPESIPIEGQSAARVFDSPDTPTIATLVDLANAREPREDGRAWTAADTLKNIVLALTHLDGTRELVVVGIPGDRDIDLKRAEVAFFPAEVEPATEGDLAKQPGLVKGYIGPWSPEGPVLGSTSSTKVRYVVDPRVVDGSSWITGANVAGKHVLSLVAGRDFTPDGVVEAADVRDGDPAPDGSGPITAGRGTEIGHVFELGRKYAEALGLKVLDENGKLVTVTMGSYGIGITRNLALVAEATQDGRGLLWPASISPFDVHVVMTGKGDEIASASEELVDALDAAGLDVLFDDRPKVSPGVKFGDAELIGVPTIVIVGRGAVDGMAELWDRRTNERTPVALADVVGALTADR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_NEOSM
Sequence: MFQVVSKTDWLTVRAYFALLKPRVVSLVTFTAVTGAVLAYFSGYHAPFFSVFTAIFCIAVGSGAAGALNMYYDRDIDAIMSRTSKRPIPQGKISPEAALVFGLVLFALSVLLMELAVNHLSAVLLSVAVFYYSVIYTVYLKRRTPQNIVVGGGAGAFPPMIGWAAVANHIGVESLVLFLIIFLWTPPHFWALALKNSGEYEAAGIPMLPVTSGVKATKMQILCYSVLLFITSILPYLLRFSGGTYMIVAFILGLVFLYYAINVYLDEKKCMKLFYYSVLYLFLLFGVFILDAALSTALGMLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3853_ECOL5
Sequence: MSDCHPVLLPEGPFSREQAVAVTTAYRNVLIEDDQGTHFRLVIRNAEGQLRWRCWNFEPDAGKQLNSYLASEGILRQ
What are the official names of this protein?
UPF0401 protein ECP_3853.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: Y2015_HAEDU
Sequence: MPQAINLKDLPQAKLKDLLEFPCAFTFKVVGIHREDLVEDVVAITQVHAKGDCNPRQQRSSKGTYNSVSIDIIAEHIDQIETLYLELAKITGVRMVL
What are the official names of this protein?
UPF0250 protein HD_2015.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: UFD1_YEAST
Sequence: MFSGFSSFGGGNGFVNMPQTFEEFFRCYPIAMMNDRIRKDDANFGGKIFLPPSALSKLSMLNIRYPMLFKLTANETGRVTHGGVLEFIAEEGRVYLPQWMMETLGIQPGSLLQISSTDVPLGQFVKLEPQSVDFLDISDPKAVLENVLRNFSTLTVDDVIEISYNGKTFKIKILEVKPESSSKSICVIETDLVTDFAPPVGYVEPDYKALKAQQDKEKKNSFGKGQVLDPSVLGQGSMSTRIDYAGIANSSRNKLSKFVGQGQNISGKAPKAEPKQDIKDMKITFDGEPAKLDLPEGQLFFGFPMVLPKEDEESAAGSKSSEQNFQGQGISLRKSNKRKTKSDHDSSKSKAPKSPEVIEID
What is the function of this protein?
Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway.  Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.  Required for the proteasome-dependent processing/activation of MGA2 and SPT23 transcription factors leading to the subsequent expression of OLE1.  Has an additional role in the turnover of OLE1 where it targets ubiquitinated OLE1 and other proteins to the ERAD.
What are the official names of this protein?
Ubiquitin fusion degradation protein 1, UB fusion protein 1, Polymerase-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the UFD1 family.
Protein: HSLU_OCEIH
Sequence: MGMDYTPRQIVEQLDQFIVGQKQAKKSVAVALRNRYRRMKLDEGFRDEIVPKNILMIGPTGVGKTEIARRLAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVEMAVRMVKEEKMAGVMNEAEEEANKRLVKLLVPESKKKPAMKNPFEMLFQSDGSDGDDETTEQDSHDEIRSKRKRIAHQLALGELEDHIVSVEIDEVPPSMFDMLQGSGMEQMGMNMQDAFGQFMPKKKKKRNLPVSEARKVLTQQEAQKLVDMDEVAQEATSRAEGSGIIFIDEIDKVAGKQENAANVSREGVQRDILPIVEGSTVVTKHGTVKTDHMLFVAAGAFHMSKPSDLIPELQGRFPIRVELEKLTVEDFKRILTEPSNALIKQYQLMLQTEGINVEFTDEAIERLAEIAYQVNQNTDNIGARRLHTILEKLLEDLSYEAPEITMEKVEITVGYVDDKLSSIVQDKDLSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.