PharMolix/UniProtQA huggingface dataset:
Protein: ARNT_ECO8A
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQAWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPB11_HUMAN
Sequence: MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB11-a, RNA polymerase II subunit B11-a, RPB11a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 13.3 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
Protein: SYT_PSEPK
Sequence: MPVITLPDGSQRSFDHAVSVAEVAASIGAGLAKATVAGKVDGKLVDACDLISNDATLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPTAKMVIGPVIDEGFYYDIAYERPFTPEDMAAIEKRMMELIEKDYDVVKKMTPRAEVIDVFKARGEDYKLRLVEDMPDEQAMGLYYHEEYVDMCRGPHVPNTRFLKAFKLTKLSGAYWRGDAKNEQLQRVYGTAWADKKQLAAYIQRIEEAEKRDHRKIGKQLDLFHLQEEAPGMVFWHANGWTVYQVLEQYMRGVQRENGYQEIKTPQVVDRILWERSGHWSNYAENMFTTSSESRDYAVKPMNCPCHVQVFNQGLKSYRDLPLRLAEFGACHRNEPSGALHGIMRVRGFVQDDAHIFCTEDQVKKEAADFIKLTLDVYKDFGFSDIAMKLSTRPAKRVGSEELWDRAETALADALNESGLEWEYQPGEGAFYGPKIEFTLRDCLGRNWQCGTLQYDPNLPERLDASYIAEDNSRVRPVMLHRAILGSFERFIGMLIEHYAGVFPAWLAPTQAVIMNITDKQADFALEVEKSLNGSGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVETQTVAVRTREGADLGSMPVAQFVELLTQAVSRRGRQESE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_BORPD
Sequence: MPATDIDTAMLALGENARRASRAMMRATGAAKNHALQAMAEALRDNRAELQAANAQDIDAARAGGLEPALLDRLTLSDKAIDRMAEGLLQVAALPDPIGSTTASALRPNGMRVAQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALHSNVALGRIVQAGLQAAALPAEAVQVVGTTDRAAVGKLITMTEHIDVIVPRGGKGLIARLASEARVPLIKHLDGNCHVYIDAAADPQKAHTIAFNAKTYRYGICGAMETLLVDAGVAVSILPRLAAAFSAHGVELRGCPRTLEIVPSATPATDDDWATEYLAPILAVRIVDSLDQAIEHIARWGSGHTDAIVTEDLSAAQRFQREVDSSSVYVNLPTCFADGFEYGLGAEIGISTNRLHARGPVGLEGLTTLKWVLNGDGQTRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_MANSM
Sequence: MARFETLFAQLNAKKQGGFVPFVTLCDPDLERSFDIICTLVDNGADALELGFPFSDPLLDGPVIQAANNRALNAGCSTAESFKLLEKVRSKYPEIPIGLLLCANLIYAQTLDGFYRRCAEIGIDAVLVADIPLLAAEPYIQAAKKHGIQPVFICPPNADENTVKGVAEHSEGYTYLVSRAGVTSAENQSHAANLDSLVEQLKAHNAPPILQGFGIAKPQQVKEALNMGVAGAISGSATVKIIEANLDNHEKCLADLAEFVKNMKAATL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RIMM_PROM3
Sequence: MNGDEDWLTVGKLVAAQGMQGELRINPSSDFPERFTLPGQRWLKERNGEPRPIELLTGRQLPGRSLYVVKFAGVNNRNAAEALVGQNLLVPSSDRPSLAEGEFHLLDLVGLEARLQAEGPAIGHVIDLTTAGNDLLEIELLAGRRVLVPFVEAIVPEVQLNQGWLRLTPPPGLLEL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROX_STRVP
Sequence: MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMEMTASQEELTSVMTEVRKTQQRFGAMPLGDGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAATAG
What is the function of this protein?
Monooxygenase that can modify rifampicin, thereby inactivating its antibiotic activity (PubMed:29398560).  Inactivates a broad range of rifamycin antibiotics (PubMed:29398560).
What are the official names of this protein?
Rifampicin monooxygenase, RIFMO.
What is the protein family that this protein belongs to?
Belongs to the rifampicin monooxygenase family.
Protein: RAYT_ECOLI
Sequence: MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKRDRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHAIRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDFSAGERIIS
What is the function of this protein?
Transposase that is always flanked by repeated extragenic palindrome (REP) sequences, which are clustered in structures called bacterial interspersed mosaic elements (BIMEs).  RayT catalyzes cleavage and recombination of BIMEs.  Binds REP sequences and cleaves BIMEs both upstream and downstream of the REP sequence.  Could be important in the creation of BIME variability and amplification.
What are the official names of this protein?
REP-associated tyrosine transposase.
What is the protein family that this protein belongs to?
Belongs to the transposase 17 family. RAYT subfamily.
Protein: RSMH_BUCA5
Sequence: MNHIFKHIPVMKKELIDSLKIKKNGIYIDSTFGTGGHSNEILKKLGQNGRLYSIDRDPIAFSIGSEIKDSRFHIINENFSKLLDFAKNEKIIGKVNGIIFDLGVSSIQIDDYRRGFSFKNDGPLDMRMNPNYGISASEWLFESNVKEISFVLKNFGEERFSRKIAYAIKRRSQIKKITSTLELANIIKKTIPTKNKFKHPARRSFQAIRIYINQELEEIQKALESTLKILKPGGRISIISFHSLEDRLVKKFMIKNSTKAIIPYGMPITEEQLNRLTTCKLKIINRILPTQNEINNNPRARSSVLRIAEIQE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSR_NEIMA
Sequence: MTDIFTTSKRSFVMLKIHSKETKPEVLVRKFLFFQGFRYRKNDKRYVGKPDIVLSKYKTVVFIHGCFWYGHSCNKGHIPKSNTDFWLEKITKNCERDIKNETELEKIGFKVIVVWECELKNKAICRERLNRLVREIKDAV
What is the function of this protein?
May nick NmeAIP sequences that contain T/G mispairs resulting from m5C-deamination.  If unrepaired, these mismatches can lead to C-to-T transition mutations.  The very short patch (VSP) repair process counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand.  This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CCGG (C-methylation site unknown) next to the thymidine residue that is mismatched to 2'-deoxyguanosine.  The incision is mismatch-dependent and strand-specific.
What are the official names of this protein?
Type II nicking enzyme V.NmeAIP, Very short patch repair endonuclease.
What is the protein family that this protein belongs to?
Belongs to the Vsr family.
Protein: AKTIP_CHICK
Sequence: MNPFWSMSAASGRKRPEADEKTLSGELRTSPPRASAKKQLPSVPKNAVPVTKPASPAMSSQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLVFDLPVFHPLVDPLSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKLCSSHLFDQPKIEDPYAIVFSPWNPAIHDEAREKMLTQKKKPEDQHCKSMHVSGLSWVKPGSVQPFSKEEKTMPT
What is the function of this protein?
May function to promote vesicle trafficking and/or fusion.  May also regulate apoptosis (By similarity).
What are the official names of this protein?
AKT-interacting protein, Fused toes protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: PYRG_HAEI8
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATIQVIPHITNEIKDRVIAGAQGHDVVIVEVGGTVGDIESLPFLEALRQLAVQVGREHTLFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPPNERAKIALFCNVAERAVISLKDVNSIYQIPALLKSQGLDDFVCERFRLTCPEADLTEWEQVLYKQANPVGEVTIGMVGKYTELPDAYKSVNEALKHAGLTNRLSVSIKYIDSQDVETKGVEVLKGVDGILVPGGFGYRGVEGKIRTAQYARENKIPYLGICLGMQIALIEYARNVAGLTKANSSEFDKDCEQPVVALITEWQDAEGNTEVRTDESDLGGTMRLGAQQCHLVSGSHARELYGKETIEERHRHRYEVNNTLLPQIEKAGLKVTGLSADKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAYENHKKSVK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TRMA_ACIBT
Sequence: MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEAYIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: HIS4_SHEPC
Sequence: MIIPAIDLIDGNVVRLYQGDYGQQTTFDLSPLAQLQSYEAQGAKWLHIVDLTGAKDPAKRQTRLISELVAELNANIQVGGGIRTEEQVTELLAIGVKRVVIGSLAVKEPELVKQWFIKYGSEAICLALDVNINQSGEKMVAVSGWQSGGGKSLESLVETFSAVGLKHALVTDISRDGTLTGANTALYQEIAAIYPDIAWQASGGIATLEDVAAVRDSGAAGIIIGKALLINQFNVAEAIQCWPND
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_BACSU
Sequence: MFKTISNFMRVSDIRNKIIFTLLMLIVFRIGAFIPVPYVNAEALQAQSQMGVFDLLNTFGGGALYQFSIFAMGITPYITASIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLANGMLIEKSGVSTYLIIALVLTGGTAFLMWLGEQITSHGVGNGISIIIFAGIVSSIPKTIGQIYETQFVGSNDQLFIHIVKVALLVIAILAVIVGVIFIQQAVRKIAIQYAKGTGRSPAGGGQSTHLPLKVNPAGVIPVIFAVAFLITPRTIASFFGTNDVTKWIQNNFDNTHPVGMAIYVALIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVISILPIFFIQFAGLPQSAQIGGTSLLIVVGVALETMKQLESQLVKRNYRGFMKN
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: TRPC_CERSK
Sequence: MSTILDRIKAYKLEEIAARKAERPLVAVEDAARAAPAPRGFARALSTAAATGYGLIAEIKKASPSKGLIREDFDVPALARAYEAGGATCLSVLTDGPSFQGADDFLRQAREAVKLPCLRKDFLYDTYQVAEARALGADCILIIMASVTDSQALELEAAASHWGMDVLVEVHSRDELARAEHLKSRLIGINNRNLDTFEVSLDVTRDLARRVPEDRLIVSESGLYTPEDLADLARYGARCFLIGESLMRQADVEAATRAILADPLTSQGGV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RS9_PSEAB
Sequence: MSATQNYGTGRRKTATARVFLRPGTGKISINNRGLDQFFGRETARMVVRQPLELTETVEKFDIFVTVVGGGVSGQAGAIRHGITRALIEYDETLRSSLRKAGYVTRDAREVERKKVGLRKARKRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL7_CLOB1
Sequence: MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAGAGAAEEKTEFDVVLADAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SYS_KORCO
Sequence: MSWSVLEALRKDPEILRENLRRRFLPLDMLERAIELDRKWREAVTELNSLRERRNEINRSIPRADPGEREELIRKAKEIGEEIERLEDVLEKLSQERDSILMSMPALIDDSVPIGPNEDYNKPIRFWGKPKVPRSKLDSFMEQTRGFNVEYELIDWEPLGHADELEVMLKQVDTVKAGQLAGSRFFYLFKDIVWLEQALILFALDKISRKGFIPVIPPYMMRRDYYLGVVDLNTFEDSIYKVEGEDLYLIATSEHPLVAMHAGDTFTEDELPRLYVGLSPCFRKEAGTHGKDTKGIFRVHQFTKVEQIVFSKPEESKYWHERLIENAEEIYRELEIPYRIVNIASGDLGASAAKKYDLEGWFPAQGKYRELVSCSNCVDWQSYRLRIKLDRKGRREFVHTLNSTALATTRTISAIVENHQREDGSVRIPKALRKYLEIFEQAPKEEIVPIEKILKE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JBP2_LEIIN
Sequence: MLNGLTRVSTSSELESILDIVQSSGEIAVVFTSPSIGDLETITSETQRRQLRIAGIPRGGYTILPAIPLYDDELLQMCERYTSANEYEKAEMRNSLYMREYPLFTYSIRHQRALFHPADYVSRILQFCSYYVQAPDADVLPLQDKSPFLHISPIKEICKHLRLIARGTPVAPDDSESPVPEQLRLHAESDAEKLAAERATAMSIATSSGGASETEQPSLFSGVAPSALFQKGAVEEVDKDAEDTMEDLTGEETVDAVHSFQAEYLTLDGFELVTKASIYYDREGEGQRVVAVYIPGGVPEDTCRAAAAVLEPAATKKNLRAPTNGGLPPDTGIVGYYDYLTNPTQHKCRETEYSRRNWGLLAQSEPLLKHLDKLYSQLAPMHHHLQRVAIPSQYQLCGTVFSTITVNRNFRTAVHTDKGDFRSGLGVLSVINGEFEGCHLAIKRLKKAFQLKVGDVLLFDTSLEHGNTEVVNPEIHWQRTSVVCYLRTGLMSSVCEMERRKHLNRLILLQLLNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLHLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQRNNEKPKLGHIFVINGEYLAGFLRRFKRFTPLLMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGAFYNAVMAQEYIQDWMRGFVFREMENDLPPLHDYLLICGSSDVQREYEEKLGLTETAMTALKATEHRPHHLSTHPACYLAFISDSYQSMVSGWTVRAQSNTSRPRVSQLEEIDTMRLEQYVQLVENEQLDAFIDLSGKMRVLVDIVLRVQARKEKLIIFSLYVGSQDLIHRTLTALRVCTFTVRGRDSQDRRRRAMQEFSENKDLIVLVLSTKIAAYGLDFTAANHVVLFDSWWNPQVDAQAIARAYRRNQRKPVTVYRLISATENKFVLRSQTRKIALFKCILHERTSRQALPDELEDCAANEKDEERRIFWAKLKTTSLAGDSRALLNVYRYQESVRESE
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Probably also acts as a DNA helicase.  Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis.  Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis.  In contrast to JBP1, it does not specifically bind DNA base J, however it binds chromatin (By similarity).
What are the official names of this protein?
Bifunctional helicase and thymine dioxygenase JBP2, J-binding protein 2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TET family. JBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MODA_MYCBO
Sequence: MRWIGLSTGLVSAMLVAGLVACGSNSPASSPAGPTQGARSIVVFAAASLQSAFTQIGEQFKAGNPGVNVNFAFAGSSELATQLTQGATADVFASADTAQMDSVAKAGLLAGHPTNFATNTMVIVAAAGNPKKIRSFADLTRPGLNVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVTDVLNKVITGQADAGLVYVSDALSVATKVTCVRFPEAAGVVNVYAIAVLKRTSQPALARQFVAMVTAAAGRRILDQSGFAKP
What is the function of this protein?
Involved in the transport of molybdenum into the cell.  Part of the binding-protein-dependent transport system ModABCD.
What are the official names of this protein?
Molybdate-binding protein ModA, Molybdate/tungstate-binding protein ModA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein ModA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GREA_CAMJE
Sequence: MQKEPMSQFGYDKLAAELKDLKDNQRPAVVIEIDTARSHGDLKENAEYHAAREKQALIESRIAELSDLLARAQVIDPSSYEHDSVKFGSSVVIMDLDTEKESKYTLVGICEGNLDKGYISIASPIAKAMLGKKEGDDFKVRLPKGESEFEILSINYEPLKF
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CU21_LOCMI
Sequence: GYLGAPAVYAPGAPIAARAYAAPVAYAAPALRAAPVAYAAPAVAKVAAPVAYAAPAAVAAEYDPNPQYSYAYNVQDALTGDSKAQQETRDGDVVQGSYSLVEPDGSIRTVDYTADPVNGFNAVVHKEAGAHPAPVVAKVAAPVAYAAPAIAKVAAPLAYAAPAYGKASH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 21, LM-ACP 21.
Protein: RSMA_BACCQ
Sequence: MKDIATPNRTKDIVEKYGFSFKKSLGQNFLIDTNVLNRIVDHAEIGSESGAIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILDETLAPYGNVTVINKDVLKADVHEVFSEQFEEGQDVMVVANLPYYITTPILFKLLEEKLPVRGFVVMMQKEVGDRLAAKPGTKEYGSLSIAIQYYTEVETVMTVPRTVFVPQPNVDSAIIRLLKRPKPVVEVTDETFFFEVVRASFAQRRKTLMNNLSNNLNGFPKDKELLDRILTEVGIDPKRRGETLSIEEFATLSNALVLHKLS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STAAB
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDESQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Y2452_BORPE
Sequence: MLFLLSPAKKLDYDSPVHVETHTQPLFVDQAAALIKVLKTKSADEIAELMSLSPALAELNAGRYGAWKRSFTQANSRQAVLAFNGDVYEGLQADTLSARQLDWAQDHVVILSGLYGALRPLDLMQPYRLEMGTRLHTPKGKNLYEYWGSGIAEYLNERQAGAKAPVIVNLASEEYFKVVDLKTLKARVVQCVFQDWKNGAWKVISFHAKRARGLMARYAIAHKVARPEGLQGFDSEGYAYDAAASSADKLVFRRKQA
What are the official names of this protein?
UPF0246 protein BP2452.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.