PharMolix/UniProtQA huggingface dataset:
Protein: ANR31_MOUSE
Sequence: MENGAEASDCDSDETVIEGSVTENEPEDEELPWRRLLLNQDTTCRSEFCFHSGVDGMQKGIHSPEIQLGLKLRKDSQEQNNKNKLLLALSEDLVLQDPQDKTAQNQVLLQTTKEFPVFTVSFPHPEVSWSHQNTGGHEAENCENLPHSKKELRENSDSPEVSLLSGTSPVAPDLVALKERLTEPVKTLAVPNTLSEPGEEVTQTMTSKETKDEESSLETFVSTLEKLLESSECTQEERLLEVMDDFNPQELFSTLSNSLGSVSVPLNAWAAQGRDELENKADAALPAKLLAAVNTGADVGPSCQGQEKSSSVSGGNGCLAVQPIMSQVDEDCTQIAQNIEDPKPFRLQTLTHENAISYEQINKKKNSDPIKNTSTQETPRVLRRSSRLEKLKASRDVVHTEAVLKKPERILSNTLSFKDQINSIFTTDSFSKRKNMHSSGFKNEQIRKSEQLRKKNGTGEMKKMCLCTINRRNVFGENLLYKAALHNDVDLVRCCIKNGENVNQPSYDGWTALHEASIGGYYQAVSELLKGGADVNVKGKYQITPLHDAVMNRHYKVAELLLMSGADPLFRSDHGTCALDEAKDSSMETLLMKYIPQQKKCHLSAQRNSTDPAHVEDMFQNKKPKLSSNNYTEFICDENFDRQEPGHLEINKGSNNLLMSKEYVCEHCQKDSNTTKFGKSNLNSVKNSRTNVSKRKGQKNRQQKKTQVDDRDCNLSQKIGTSSFRRTNKLLTQQQHAVQTLSDLPEESFELSTTTLSSLENGIGYNEACLVSKKSDTHVLDSSDGQELESVDQTEAASVSELSSYKEIKLLPVTTHQQPHTNQEQYSSPYKSLGNNSSNEKGKATNKWEDSFFSFIKGRSADSDSDCHTLDKSIASPKEGMSHDHHEEIMTGQEVDSQQRLSSENYFSQENDLKVHPLTTHPQEEAVNFCDSNLISVQHTPDYKNCLHEISFGNSYAKTEQSSTSCTRPPSTQKVSPLTVEVELLKGLQDSLAHRDSSPLVNQAGIHSLERKQDTDKNYTKKGPNTSSSSRPLPTVVHSQVIEITKAEKRREDLPGNEPINNTDFYSTDINKELANSSQLNQRKEKENVRKSDAELTHNDSEAERTLKSCEEKKKNMDSETHSPCDIQEHRKDQNFRKRKCSLKAPCSQGVNTTGIGKRNKKGESQLHVAARGGNLSRVKVLIEARADVNLRDNAGWTPLHKAASGGFDDVIIELLQAGANVNCENIDGIVPLHGASAGNHLKAAEILLEHGANPNQKDQKQRTALDEADDEKMKELLKSYGAIESTNGEKRNSTDLVKIPTVQPKRYKQFICDNDKAIGSPVPSHKAKKSESLPVHQTISAILQDIEEKQENLLKLEIRNSEDEEQYIGKMLEIKEVMDNILAQQKTERDDLAKKYRVSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKNATAVSGVGLRKLPCNSDISSDKKSQEPPTMGDSAHAQPGLLAPVSLAYGSMQEIPLSPEIESESQKINICLNAEAIRREEFSGNDINSKQNVQDCTLGGLLRSKPTDDAEKIASSSQPAALTPHAENSQAEATVKGCGFDSSALTGTINISEDKSIFSPNGACLAADPHSQKLSRCNPKRRNKKTASQQPSAGAAEPLPQAPAVLDTYTVHQTLPCLRDSAAAASHTDSTQSSLSSASAHQHPTKTVPHRNTTPRKKAVQLKDLILRGRINPGNNILEFKTQETTHRASVLPSGKLKGENGQIYQNPVTWLKELLGGGSYVTWNYAWNTVTYLGRELVKCVSEEAPMSAELNPPQLHQPHLSAGTSRESMQTIPHYLQIKEILQISKQELLPCHVMEQHWKFYVGRSHSEALLSW
What is the function of this protein?
Required for DNA double-strand breaks (DSBs) formation during meiotic recombination (PubMed:31003867, PubMed:31000436).  Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation (PubMed:31003867, PubMed:31000436).  Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes (PubMed:31000436).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 31.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes on chromatin between preleptotene and early pachytene (PubMed:31000436). Associates with the chromosome axes, but disappears from axes upon synaptonemal complex formation (PubMed:31000436).
Protein: AMPA_HELPJ
Sequence: MLKIKLEKTTFENAKAECSLVFITNKDFDHVWVKNKKLLETFKYEGEGAFLDQENKILYVGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCDTHAKDNALLENLKALFLGLKLGLYEYDTFKPNKKESVLKEVIVALELHKHCEKTCANSLEKSAKEALKYAEIMTESLNIVRDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLAVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLSPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ANADE
Sequence: MPSLRDIRTRIGSVRSTRQITKAMKMVSAAKLRRAQDAVLKTRPYAMLLDQTLSRLAARAAAEEQVAHPLLAPRAQRTAEVVVVTSDRGLAGGFNSNICRFVQRFLTENADRFERIALATVGKKGREYFKARNLPIRRDYTGIHANLAYEKAEALAREATERYLAGEVDAVFLAYNEFKSAISQKQAVVQLLPVDTSAASADTAGVDFRYEPSREALLADLLPRHVAMQVWRALLESAASEHGARMSAMESATKNAEEMIASLSLQYNRARQAYVTKELSEIVSGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y355_SYNY3
Sequence: MQIESKTNTNIRSGLTLIAPFFLWGTAMVAMKGVLADTTPFFVATVRLIPAGILVLLWAMGQKRPQPQNWQGWGWIILFALVDGTLFQGFLAQGLERTGAGLGSVIIDSQPIAVALLSSWLFKEVIGGIGWLGLLLGVGGISLIGLPDEWFYQLWHLQGLSINWSGSALGSSGELWMLLASLSMAVGTVLIPFVSRRVDPVVATGWHMIIGGLPLLAIALVQDSEPWQNIDLWGWGNLAYATVFGSAIAYGIFFYLASKGNLTSLSSLTFLTPIFALSFSNLILEEQLSSLQWLGVAFTLVSIYLINQREQLKIQLRDIWSLVRKPVIND
What are the official names of this protein?
Uncharacterized transporter sll0355.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATLA_ARATH
Sequence: MMSGSRLASRLIIIFSIISTSFFTVESIRLFPDSFDDASSDLMEAPAYQNGLDCSVLAKNRLLLACDPSAVHIAMTLDPAYLRGTVSAVHSILKHTSCPENIFFHFIASGTSQGSLAKTLSSVFPSLSFKVYTFEETTVKNLISSSIRQALDSPLNYARSYLSEILSSCVSRVIYLDSDVIVVDDIQKLWKISLSGSRTIGAPEYCHANFTKYFTDSFWSDQKLSSVFDSKTPCYFNTGVMVIDLERWREGDYTRKIENWMKIQKEDKRIYELGSLPPFLLVFGGDIEAIDHQWNQHGLGGDNIVSSCRSLHPGPVSLIHWSGKGKPWVRLDDGKPCPIDYLWAPYDLHKSQRQYLQYNQELEIL
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase-like 10, Galactinol synthase 8, AtGolS8, GolS-8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: SORCN_CRIGR
Sequence: MAYPGHPGAGGGYYPGGYGGAPGGPSFPGQTQDPLYGYFASVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTSGKITFDDYIACCVKLRALTDSFRRRDSAQQGMVNFSYDDFIQCVMTV
What is the function of this protein?
Calcium-binding protein that modulates excitation-contraction coupling in the heart.  Contributes to calcium homeostasis in the sarcoplasmic reticulum in the heart.  Modulates the activity of RYR2 calcium channels.
What are the official names of this protein?
Sorcin, 22 kDa protein, CP-22, V19.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels and phosphorylation.
Protein: DEF_CLOB8
Sequence: MIKPIVKDILFLGQKSEEATKNDMVVIDDLIDTLRANLEHCVGLAANMIGVKKRILVFTVGNLIVPMINPVILKKEKPYETEESCLSLIGFRKTKRYETIEVTYLDRNFNKKKQVFNGFTAQIIQHEMDHFEGIII
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NUOH_BACC7
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPIGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNTH2_PSEAE
Sequence: MSAKDTPAPQAAEPGRAQPVEVPGGGHWWRRLLAFAGPGYLVAVGYMDPGNWATDVAGGAQLGYLLLSVILLSSLMAMLLQALSARLGIASGLDLAQACRERYSPSTCRLLWLACETAIIACDLAEVIGTAIALKLLFGLPLAWGALLCVGDALLVLVLIGRGQRPLEAFVVALLTLIFACFAVQLLLSRPELGEVLQGFLPSPRVLSDPAALYLAIGIVGATVMPHNLYLHSSLVQSRAYPRSLAGKRKALRWAVADSSLALTLALLVNAAILIVAASVFHRNGHTEVVDIEQAHALLSPLLGLELASLLFAVALLASGLNSTVTTTLAGQIVMEGFLRLRLAPWARRLLTRGVAVLPVLLVTLLYGEDGTARLLIFSQVILSMQLPLAVIPLLQFVSDRRLMGPLAIGAGTRWLAWAVALAIVGLNLQLLADFAFG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH 2.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR18_NYMAL
Sequence: MEKFKRPFRKSKRSFRRRLPPIGLGDRIDYRNMSLISRFISEQGKILPRRVNRLTLKQQRLITIAIKQARILSLLPFLNNEKQFERAESISRTTGTRTRKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS19_HALWD
Sequence: MSSEYRTGREGEFTYRGHTLDELQAMSLEDITALLPARQRRTIERGLTTEQQKLRETVRDADPQKTANDPIRTHLRDMPILPSFVEKTIAVYNGQSFERVRIEPEMIGHYLGEFQLTRTSVEHGQAGIGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CCMA_SPHAL
Sequence: MTVLLALDGVACIRGDRLVFEELSLALNRGDALWVRGPNGAGKSSLIRLAAGLLRPAAGRVVRRGRIALIDEAAALDSELPLRRALDFWARVDTVDGHAVDRAMDMMALNTLADVPVAMLSTGQRRRAAMVRVIASGAPIWLLDEPANGMDQAATARLVAAIATHRANGGAVLLASHFALAIPDLDELVMGVLA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYFA_STRP1
Sequence: MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLTELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLPGRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQIEGLVVGKNISMGDLKGTLEMIIKKMFGDERSIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRGFYQGDQRFSEQFN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAP8_ADECG
Sequence: GSRSSFSPTQAFLTLQQASSTPRTGGVGSYQFVREFVPEVYLNPFSGPPDTFPDQFIPNYDIVTNSVDGYD
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
What are the official names of this protein?
Pre-hexon-linking protein VIII, Pre-protein VIII, pVIII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein family.
What are the subcellular locations of this protein?
[Pre-hexon-linking protein VIII]: Host nucleus. SUBCELLULAR LOCATION: [Hexon-linking protein-C]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion.
Protein: SCNNA_CHICK
Sequence: MGTASRGGSVKAEKMPEGEKTRQCKQETEQQQKEDEREGLIEFYGSYQDVFQFFCSNTTIHGAIRLVCSKKNKMKTAFWSVLFILTFGLMYWQFGILYREYFSYPVNLNLNLNSDRLTFPAVTLCTLNPYRYSAIRKKLDELDQITHQTLLDLYDYNMSLARSDGSAQFSHRRTSRSLLHHVQRHPLRRQKRDNLVSLPENSPSVDKNDWKIGFVLCSENNEDCFHQTYSSGVDAVREWYSFHYINILAQMPDAKDLDESDFENFIYACRFNEATCDKANYTHFHHPLYGNCYTFNDNSSSLWTSSLPGINNGLSLVVRTEQNDFIPLLSTVTGARVMVHDQNEPAFMDDGGFNVRPGIETSISMRKEMTERLGGSYSDCTEDGSDVPVQNLYSSRYTEQVCIRSCFQLNMVKRCSCAYYFYPLPDGAEYCDYTKHVAWGYCYYKLLAEFKADVLGCFHKCRKPCKMTEYQLSAGYSRWPSAVSEDWVFYMLSQQNKYNITSKRNGVAKVNIFFEEWNYKTNGESPAFTVVTLLSQLGNQWSLWFGSSVLSVMELAELILDFTVITFILAFRWFRSKQWHSSPAPPPNSHDNTAFQDEASGLDAPHRFTVEAVVTTLPSYNSLEPCGPSKDGETGLE
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1A subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cytoplasmic granule. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
Protein: RS7_PROMM
Sequence: MSRRNAAEKRPVLPDPQFNNRLATMMISRLMKHGKKSTAQRILAQAFGLINERTGGDPIELFETAVKNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVNFSRARNGRSMSQKLAAELMDAANEAGSAVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TXG8A_ETHRU
Sequence: MTSTRKLSVSCLIVFMVSSLIAVSSGWLSSTGKSPLKIGKCDPKNGNLYAIGRKWYNDEDCFEITCIQGDKGSVAQQVASCPVHAVKPGCELVFPGGTYPKCCPYYECPNS
What are the official names of this protein?
U-scoloptoxin(16)-Er8a, U-SLPTX(16)-Er8a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIC_LEPCP
Sequence: MNAPDKLQDLLSLTREPFPASRKVYAEGSEGVRVPMREIALTNGERVTVYDTSGPYTDPLATIDAKLGLPSVRTGWIEARGDTETYAGRNRVALDDGGKHEETARIEALRAQAAALQRTPRRAKAGGNVTQMHYARRGIVTPEMEYVAIRENGKREWMREYLGDAEREARLAGNAKGARIPEIYTPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFGVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGRNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWAIYRDTLIEQAEQGVDYFTIHAGVRLPFIHLTANRRTGIVSRGGSILAKWCITHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSASDANDAAQFAELKTLGELTQVAWKHDVQTMIEGPGHVPMHLIQANMDEQIKHCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADIAKGHPGARARDDAMSKARFEFRWHDQFNLGLDPDTARDYHDETLPKDSSKEAHFCSMCGPKFCSMKITQDVRDYAAAKGLSEEQALADVEQGMAAKSAEFKAQGGELYIPITPVQA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: OBG_THEYD
Sequence: MQFIDYVKIYVKAGDGGRGCISFRREKYVPKGGPDGGDGGKGGDVIIQASSELHTLLDHRYQKVYKAQRGQHGKGSNMKGKDGENLIIKVPVGTVVKDAETEEVLADLDEEEKYFIVAKGGRGGFGNAHFATPTNQAPRYAQPGEKGQERWVILELKLLADVGLIGLPNAGKSTLISVISSAKPKIADYPFTTLIPVLGVVKYENYQSFVVADIPGLIEGAHKGAGLGHQFLRHVERTSLLLHLVDVSDFSESDPREDFEKIQKELELYNPALTKKPFAVVGTKIDIAYKGDRLGKLKKYCEEKGIDFFPISAVKKEGIDKLLHYLSEKVGKKCGLL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RND_GLUDA
Sequence: MARTSKAGFPDPVLITTTEDLTGVVERLRREPFVSIDTEFVRERTYWPELCLVQLAGQDEVVVVDTLAPGIDLAPLGVLLDDPEVVKVFHAARQDLEIFLYLFGHLPAALFDTQVAAMVAGFGDQVGYDNLVASLTGAHIDKAHRFSDWSARPLSEAQIAYAAADVTHLRTVYQLLLERLEREGRLDWVASDLAVLSDPATFRPDPETLWERMRPRTSNRRMLGVLRAITAWREREAQRVNVPRQRLLKDESLLEIAATAPADVDALARIRGVSRGFAEGKSGTGILEAVAAARALPDGALPRQQKGKEGPRPSPALVALLKVLLAACCEEHDVAPRLVASSEDLDRLALEPEPDLPLLQGWRRTVFGDEALALKDGRMLLGVDGTRVKRIPA
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTB_BACC1
Sequence: MSMKISEKKFNDRVGDGIQDSFMRGAVSSAQTRLYTNRLKAADELGNWEEWRELGEEIRQHTLENLDYYLMQLSENVSKRGGHVYFAKTKEEAAKYIQDVAKKKQAKKVVKSKSMVTEEISMNHALEEIGCEVLESDLGEYILQVDNDPPSHIIAPALHKNRTQIRDVFKEKLGYENSDDPYEMTKFVRKQLREKFMDAEIGVTGCNFAVANTGSLCLVTNEGNADLVMSIPKTQIAVMGMERMVPTMEELDVLVGLLCRSAVGQKLTSYVTVAGPIQEEEVDGPEEFHLVVVDNGRSQILGSEFRQVLQCIRCAACVNVCPVYRHVGGHSYGSIYSGPIGAVLTPLLGGYDDYKELPYASSLCGACTEACPVKIPLHDLLLKHRQVIVEQEGRAPLAEKLAMKMFSMGASSAALYKMGSKMAPAAMSPFTSGNRVSKGVGPLKNWTDIREFPAPSKERFRDWYKDHKKGGDK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: OLF15_MOUSE
Sequence: MEVDSNSSSGSFILMGVSDHPHLEIIFFAVILASYLLTLVGNLTIILLSRLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLKNLWGPDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCRPLHYMTVMNPRLCWGLAAISWLGGLGNSVIQSTFTLQLPFCGHRKVDNFLCEVPAMIKLACGDTSLNEAVLNGVCTFFTVVPVSVILVSYCFIAQAVMKIRSVEGRRKAFNTCVSHLVVVFLFYGSAIYGYLLPAKSSNQSQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALGRLLGKGRGAS
What is the function of this protein?
Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanetiol (MTMT) (PubMed:29659735).  Also binds odorants acetophenone and benzaldehyde (PubMed:25901328).  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (Probable).  May be involved in the molecular processes underlying fasciculation and targeting of olfactory axons (PubMed:15342743).
What are the official names of this protein?
Olfactory receptor 15, Odorant receptor OR3, Olfactory receptor 256-17.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUCB_SOLLC
Sequence: MLRKLANQSLSVAGKWQQQQLRRLNIHEYQGAELMSKYGINVPKGVAVASLDEVKKAIQDVFPNQSEVVVKSQVLAGGRGLGTFKNGFQGGVHIVKADQAEDIASKMLGQILVTKQTGAQGKVVSKVYLCEKMSLVNEMYFSIILDRATAGPLIIACRKGGTSIEDLAEKFPDMIIKVPIDVFKGISDADAAKVVDGLAPKVADRNDSIEQVKKLYKLFCETDCTMLEINPLAETSDNKLVAADAKLNFDDNAAYRQKEIFSLRDSSQEDPREVAAAKADLNYIGLDGEIGCMVNGAGLAMATMDIIKLHGGTPANFLDVGGNATEGQVVEAFKILTADEKVKAILVNIFGGIMKCDVIASGIVNAAKQVQLKVPVIVRLEGTNVEQGKRILKESGMKLITAEDLDDAAEKAVKALA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, Succinyl-CoA synthetase beta chain, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MYL6_RAT
Sequence: MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELLRMVLNG
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light polypeptide 6, 17 kDa myosin light chain, LC17, Myosin light chain 3, MLC-3, Myosin light chain alkali 3, Myosin light chain A3, Smooth muscle and nonmuscle myosin light chain alkali 6.
Protein: TRPE_NEIG1
Sequence: MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKAGGKHVDVYQNGEIVEQYDGNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETVYNFEHFAHRLKNTAKANPLGTPDILLMLSQELAVIDNLSGKIHLIVYADPSQPDSYERARERLEDIRTQLRQSCAIPLSLGSKQTQAVSEFGEEPFKACVDKIKDYIFAGDCMQVVPSQRMSMEFTDNPLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGCLKEGVTNMDILAATFPAGTLSGAPKVRAMEIIEEIEPEKRGIYGGAVGVWGFNNDMDLAIAIRTAVIKNNTLFIQSGAGVVADSDPTSEWQETQNKARAVVRAAQMVQEGLDK
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.