PharMolix/UniProtQA huggingface dataset:
Protein: MEPS_ECO57
Sequence: MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVGSETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTFREQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHASTSSGVIISSMNEPYWKKRYNEARRVLSRS
What is the function of this protein?
A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links.  Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion.  Functionally redundant with MepM and MepH.  Also has weak LD-carboxypeptidase activity on L-mDAP-D-Ala peptide bonds (By similarity).
What are the official names of this protein?
Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase, Lipoprotein Spr, Murein hydrolase MepS.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: POK10_HUMAN
Sequence: NKSRKRRNRVSFLGAVTVEPPKPIPLTWKTEKPVWVNQWPLPKQKLEALHLLANEQLEKGHIEPSFSPWNSPVFVIQKKSGKWHTLTDLRAVNAVIQPMGPLQPGLPSPAMIPKDWPLIIIDLKDCFFTIPLAEQDCEKFAFTIPAINNKEPATRFQWKVLPQGMLNSPTICQTFVGRALQPVREKFSDCYIIHYIDDILCAAETKDKLIDCYTFLQAEVANAGLAIASDKIQTSTPFHYLGMQIENRKIKPQKIEIRKDTLKTLNDFQKLLGDINWIRPTLGIPTYAMSNLFSILRGDSDLNSQRILTPEATKEIKLVEEKIQSAQINRIDPLAPLQLLIFATAHSPTGIIIQNTDLVEWSFLPHSTVKTFTLYLDQIATLIGQTRLRITKLCGNDPDKIVVPLTKEQVRQAFINSGAWQIGLANFVGLIDNHYPKTKIFQFLKLTTWILPKITRREPLENALTVFTDGSSNGKAAYTGPKERVIKTPYQSAQRDELVAVITVLQDFDQPINIISDSAYVVQATRDVETALIKYSMDDQLNQLFNLLQQTVRKRNFPFYITYIRAHTNLPGPLTKANEQADLLVSSALIKAQELHALTHVNAAGLKNKFDVTWKQAKDIVQHCTQCQVLHLPTQEAGVNPRGLCPNALWQMDVTHVPSFGRLSYVHVTVDTYSHFIWATCQTGESTSHVKKHLLSCFAVMGVPEKIKTDNGPGYCSKAFQKFLSQWKISHTTGIPYNSQGQAIVERTNRTLKTQLVKQKEGGDSKECTTPQMQLNLALYTLNFLNIYRNQTTTSAEQHLTGKKNSPHEGKLIWWKDNKNKTWEIGKVITWGRGFACVSPGENQLPVWLPTRHLKFYNEPIGDAKKRASTEMVTPVTWMDNPIEVYVNDSIWVPGPIDDRCPAKPEEEGMMINISIGYRYPPICLGRAPGCLMPAVQNWLVEVPTVSPISRFTYHMVSGMSLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANSAVIL
What is the function of this protein?
Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA.  The RNase H domain of the reverse transcriptase performs two functions.  It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid.  Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome.  Endogenous Pol proteins may have kept, lost or modified their original function during evolution.
What are the official names of this protein?
Endogenous retrovirus group K member 10 Pol protein, HERV-K10 Pol protein, HERV-K107 Pol protein, HERV-K_5q33.3 provirus ancestral Pol protein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
Protein: NADE_MYCGE
Sequence: MTNLIKYLKELQNWLFDYVKKSKAKGVIFGLSGGIDSAVVAAIAKETFGFENHLALIMHINNSKLDFQATSELVKKMQFNSINIELEESFNLLVKTLGIDPKKDFLTAGNIKARLRMITLYAYAQKHNFLVLGTGNFVEYTLGYFTKWGDGACDIAPLAWLLKEDVYKLAKHFNIPEIVITRAPTASLFEGQTDETEMGITYKELDQYLKGDLILSSEKQKIVLDLKAKAEHKHNSPLKFKHLYNFQN
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: SSPF_PRIM1
Sequence: MSRRRGIMSSKLKEELAKELGFYDTVQAEGWGAIRAKDAGNMVKRAVELAQQQLKQ
What is the function of this protein?
May play some important role in either sporulation or the dormant spore.
What are the official names of this protein?
Protein SspF.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: NIFX_RHOCA
Sequence: MSRTLRLVEPAGPAPGEKPLRVAIASNDLENLDAHFGSARQIAVYEVWKTGARFVEVHQFSSATDQKGRHDELEDRIGPKLEALSGCTLVFALAVGGPSAARMVRAGMHPIKRKEPEPISAVIEQVQVMLNGTPPPFLRKVLGTWEKPDFTADFEEEEV
What is the function of this protein?
May play a role in the processing of the iron-molybdenum cofactor.
What are the official names of this protein?
Protein NifX.
What is the protein family that this protein belongs to?
Belongs to the NifX/NifY family.
Protein: APT_MARMM
Sequence: MDLKSAIRTIPDYPEPGIQFRDVTTLIGDARAFRVAIDRMVQPWAGAKIDKVAGTEARGFILGGAVAHQLSVGFVPVRKRGKLPWRTLREDYELEYGQDTIEIHVDAIAEGDRVLLVDDLIATGGTAEASIKLLQRAGATVVGATFIIDLPELGGAERIEAMGVPVSSLVAYEGT
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PSEPG
Sequence: MSTTPATPKVGFVSLGCPKALVDSERILTQLRMEGYEVVPTYEDADVVVVNTCGFIDSAKAESLEVIGEAIKENGKVIVTGCMGVEEGSIRDVHPSVLSVTGPQQYEQVVNAVHEVVPPRQDHNPLIDLVPPQGVKLTPRHYAYLKISEGCNHSCSFCIIPSMRGKLVSRPVGEVLSEAERLVKAGVKEILVISQDTSAYGVDVKYKTDFWNGRPVKTRMLELCEALSSLGAWVRLHYVYPYPNVDDVIPLMAAGKILPYLDIPFQHASPKVLKSMKRPAFEDRTLARIKNWREQCPELVIRSTFIVGFPGETEEDFQYLLDWLTEAQLDRVGCFQYSPVEGAPANDLGLEEVPDDIKQERWDRFMAHQQAISTARLQLRIGKEIEVLIDEVEEQGSVGRSFFDAPEIDGNVFIDGDHGFKPGDKVRCRVVDADEYDMWAEPI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCC1_METAN
Sequence: MSFAGMLNRLHGQPESYDKKSKYKFGRTLGAGTYGVVREADGPSGKVAIKIILKKNVKGNEKMVYAELDMLQRLTHPHIVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLHDNDVVHRDLKPENLLYVTRDPDSDLVLADFGITKTLDIKEETLTTMAGSFGYAAPEVMEQKGHGKPVDMWSMGVITYTLLCGYSPFRSENLRDLLRECTAAPVPFHERYWKDVSQDAKDFILVLLVPEPEKRWTSKEALGHIWLSGKNATDHNLLPELEAYRRRARLRRVIEIVKLQNRIAKLKEHEEDPSESDMGDAQGASDNHKGDGSRLHALGLFAVREAKQKQESLQVEEELEKESRRRSFSNA
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: CBID_THEAC
Sequence: MTQSNPFQQYGITSGLAAAAAAKASVLAAMGTISDYVGVPTPIGLRIEVKVEMMKQIDARSGIAAVRKFSGDNPDTLNGALFESRAVIRDDGLINIFAGEGIGVAVSDGLPVRRGDPAINPVARMMIENAVREVSGSAGFDVYISVPGGEDLARDTMNPRVGISGGISILGTTGIEEPVSGPDYEAHIEYLLQTGRCVSTVAVMCPGNTAMRFAESYLRLHPASFILTGDRIGSAIEMAIEKGYREIVVFGLPGKLVKMAAGVMNTHSRIADARFETIAAYAALNGADRDTISKILSSNTVESAFAVLRSIGLLDSVAGAIASRIVERLRSPVWQIRRILLRHDRFRRQAIRVSPVAGHIETGE
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: DDL_SYNSC
Sequence: MPSSPITVGLVFGGRSGEHDVSIRSAATVVRGLRSGENTERYTVQPIYIDRDGRWWGTDLAEATLTSEVAPELTTPRPPSGFQGFPEGCDAIDLWYPVLHGPNGEDGTIQGLFQLTGKPFVGAGVLGSAVSMDKQAMKSAFSSAGLSQVPYVALHASELEDAKSRSALLDRIERELNYPCFVKPANLGSSVGISKVRSRQELEAGLEQAAALDPRLVVEQGVNAREVECAVLGRRTLEASVIGEVRFDADWYDYETKYTAGRSTTLIPAPLPDPVRDRIREQALQACAAVGVHGMSRVDFFYDETNDQLWINEINTLPGFTAQSMFPMLWAASGVTLEQLVHKLIQTAGE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CHLFF
Sequence: MVLGVVGISYREAALKEREAVINILKTFEADTLLAQRFFGGDGSFVLLLTCHRAEIYYFSKSNANVQSKLLSWISSLGTRPYCYQGLACFTHLFTVTSGMDSLIFGETEIQGQVKRAYIKAKTDRELPFALHFLFQKALKEGKDFRSQVSLSYPVVTMESIVEETLDLHGKSTKDKLLFIGYSDVNRKIAKGLSAKGYRNLIFCSRKNIPIPYDTVARSQLSFGKPYDVIFFGSSESARDFPGLSLESLAGIPNRVVFDFNVPRTFTLVERPEGISYLDMDFISERVQKKLQISKQCTNKEKPFLALAARKQWEVYEKKSSNISLSQIRTSRPKLLIL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RFP4B_DANRE
Sequence: MSIQECPESPMLEGEEGRGVERDSDRDSAVDSASEISDGGRTGEKEEGIGICLPREKGDLMHNHFEISDQSALSSASLNEEQFEDYGEGEDGDCTTSSPCPDDEIRINGCSDLGSSVSSSAGQTPRKIHNVDDQMEVFCSQCCKRVSLLSDLENRLKNLKTSSPNRKISSTAFGRKLLHNSNISSSNGSTEDLFHDSTDSSDLDITEKVSYLDKKVTELENEILMSGDVKTKLKQENIQLVHRIHELEEQLKDQETRAEKIMEDELRRHRDAYIRLEKDKNTQIELLRNRLHQLEDENGKMAMNMNRLKSQTEKLDEEKQRMTDKLEDTSLRLKDEMDLYKKMMDKLRQNRQEFQRERDTMQELIEDLRRELEHLQLYKLEAERAGRGRRSSISLSEYSSRTRESELEQEVRRLKQDNQKLREQNEDLNGQLLSLSLHEAKNLFATQTKAQSLAMEIDHASRDQLLEALKQQEEINLRLRQYMDKIILSILDHNPSILEIKN
What is the function of this protein?
Acts as a regulator of endocytic traffic by participating in membrane delivery.  Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity).
What are the official names of this protein?
Rab11 family-interacting protein 4B, FIP4-Rab11-B, Rab11-FIP4-B.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis.
Protein: FABH_LISW6
Sequence: MNAGILGVGKYVPERILTNFDLEKMMETSDEWIRTRTGIEERRIARDDEYTHDLAYEAAKVAIENAGLTPNDIDLFIVATVTQEATFPSVANIIQDRLGAKNAAGMDVEAACAGFTFGVVTAAQFIKTGAYKNIVVVGADKLSKITNWDDRATAVLFGDGAGAIVMGPVSDDHGLLSFDLGSDGSGGKYLNLDENKKIYMNGREVFRFAVRQMGEASLRVLERAGLEKEDLDLLIPHQANIRIMEASRERLNLPEEKLMKTVHKYGNTSSSSIALALVDAVEEGRIKDNDNVLLVGFGGGLTWGALIIRWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_HALH5
Sequence: MVMTDPISDMLTRIRNANTVRHEKLELPASKIKKEIAEILKREGFIRDYEYIEDSKQGVIRIFLKYGSSNERVITGLKRISKPGLRVYAKAGELPRVLGGLGIAIVSTSKGVMTDKEARQQQVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PBPH_BACSU
Sequence: MTEIGREPKKKSKGNRAIRMNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTEDKIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAIYTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKTLYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSRGYDLQLSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKGATVLAGYQDGIPHYKYYIDAPMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLKMRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQPRIVTSIHKPGKKDQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGYYPSKKPKVAFSVVVPSVDDDDKINKIIAKRAIHAYAELEKKHSKK
What is the function of this protein?
Involved in the polymerization of peptidoglycan.  Plays a redundant role with PBP-2A (pbpA) in determining the rod shape of the cell during vegetative growth and spore outgrowth.
What are the official names of this protein?
Penicillin-binding protein H.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TLP_GEOSW
Sequence: MAHHRPKPDDRSDNVEKLQDMVQNTIENIEKAEETMQFASPEEREKIAEKNKRREEAIAAMRAEIKDEAAARENGYR
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: GLGC_SHISS
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: Y2084_MYCTU
Sequence: MPVSDDSSSAFDLICAEIERQLRGGELLMDAAAASELLLTVRYQLDTQPRPLVIVHGPLFQAVKAARAQVYGRLIQLRHARCEVLDERWQLRPTGQRDVRALLIDVLNVLLAAITAAGVERAYACAERRAMAAAVVAKNYRDALGVELQCNSVCRAAAEAIHALAHRTGATEDADCLPPVDVIHADVTRRMHGEVATDVVAAGELVIAARHLLDPMPRGELSYGPLHEGGNAARKSVYRRLVQLWQARRAVTDGDVDLRDARTLLTDLDSILREMRTAATIQQSGTAGDGGGGRRQDSRRRNGPRRPARRGTSRGRRCAPRVAIGWHTPIGDPLAVEGVEEIGASLPGRESTPSDDGGSLHPSGRPRRVHRRRWCGLGLC
What are the official names of this protein?
Uncharacterized protein Rv2084.
Protein: RSXA_ECODH
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RET3_PIG
Sequence: FQPSLVLDTAKILLDNYTFPESLMG
What is the function of this protein?
IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.
What are the official names of this protein?
Retinol-binding protein 3, Interphotoreceptor retinoid-binding protein, IRBP, Interstitial retinol-binding protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Note=Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells.
Protein: RS10_PHEZH
Sequence: MDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTRIEKFTVNRSPHIDKKSREQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NNRE_LEUGG
Sequence: MQLVTASEMQKIDTYTVNTIGMPQDVLIERAALSVIDVIGAGHFNLEHILVLAGLGNNGADGVAITRLLYAQGFNVSLQFVGNVSRAKESVQRQLAIIEKYGLVRSEKSDFNEATLIIDAIFGTGLNNLLPEGLQKMIKAANHIEKTVIAIDTPTGIDATTGEVRGAALKAHTTVTFGYNKIGLTRRVGGYLSGNVIVKDIGLLTPPDFSFSDTEENHSTKDV
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: PRIB_CROS8
Sequence: MANRLVLSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGHENQAVTHSITVGTQITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: RL6_CERS5
Sequence: MSRIGKKPVPLPKGVTASISGQTVEVKGPKGTRTFSATDDVTIALEEGTVKVTPRGTSKRARQQWGMVRSQVENLVTGVTAGFKKELEITGVGYRAQMAGNVLKLSLGYSHDVNFEVPAGVTVTTPKQTEITVEGIDQQLVGQVAANIREWRRPEPYKGKGIRYKDEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FDHD_BACP2
Sequence: MNPSVKKKRVIHQYREGQFTCKTDEVVEEFPLTVIVNGEEFVTLVCSPDHLKELVIGFLASEGVIRFENEIKRFTIDESMGFAYVDLVHSSEFQSSDFTKRVIGSCCGKGRHFYFLQDVKTAKTAIDRINISADTCMRLMKSLQEESQLFQHTGGVHNAGLCDTEKLFITRTDIGRHNALDKIYGYCLLHQIPLRDKILVFSGRISSEVLLKAAKLGVSIVISKSAPTELALNMAEELNITTVGFVRGESFNIYTHHQRITE
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_MYCLE
Sequence: MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDCIFQVEVPTEEVTEIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAAAEAGGLERSIIEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: ACBG1_MOUSE
Sequence: MPRGSEAGYCCLSRDSNMPDSRDDQQQGASLGTSQDNSQTSSLIDGQTLSKESPSHGLELSAPEKARAASLDGAEEALWTTRADGRVRLRLEPFCTQRPYTVHQMFYEALDKYGNLSALGFKRKDKWERISYYQYYLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYISHDCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQDADGIGEICLWGRTIFMGYLNMEDKTCEAIDSEGWLHTGDMGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLDPETSEPTDSLTEQAVEFCQRVGSKASTVSEIVGQRDEAVYQAIHEGIQRVNANAAARPYHIQKWAILQRDFSISGGELGPTMKLKRLTVLEKYKDIIDSFYQEQKQ
What is the function of this protein?
Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity) (PubMed:11112418, PubMed:12975357, PubMed:14516277).  Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (PubMed:11112418, PubMed:14516277).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase ACSBG1, Acyl-CoA synthetase bubblegum family member 1, mBG1, Gonadotropin-regulated long chain acyl CoA synthetase, GR-LACS, Lipidosin.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Microsome. Endoplasmic reticulum. Cell membrane.
Protein: CYP3B_MAGO7
Sequence: MLPRSLGHSTSELSPPFDGPNGVERYVSETRSLLRKGYEKYLRRGVPFQMRNPVEELGAQVVLPPKYLDEVKRAPTDLFSFEAYSEKAFLLNYSRAPRQTEAAAHIVRVDLTRNLGKLITFYSDFAIFEVCLPLVLIRDLGALVTDLWNESALYLDKTYNSEWQTKQAYEVVCGFVARVTSVAMVGAPLCRNPVWNRIVVETTMASFGAAQAIKDKYSARWRWLAPWSESIQKDLRRIRKESIELLKPLYEDRKAAVSRSDDVQGSSEMFRDTLYWLITSNQKDRSLSGITESQLFLSLAAIHTTSATLNSFVYDWIAHPEYHGEILAEVKETLAQVQLNGGKWTLQHVAMLRKLDSFMKESARINPIGFVSIQRYTLKPYTFKDGFQLPAGVSFVFHSDGVHHDADNYPDPEKFDAYRHLHLRETVDPNRFHFASVSDSALGFGAGNHACPGRFLSAIIMKFFLIQFMTAYEMKYEHGGIERLPNHDNSNTTAPNRTVNLLVRRCDGTSNNA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of a tyrosine-derived cytochalasan acting as a fungal signal recognized by resistant rice plants and leads to avirulence in Pi33 resistant rice cultivars (PubMed:18433432, PubMed:31644300).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS ACE1, assisted by the enoyl reductase RAP1, that are responsible for fusion of the tyrosine precursor and the polyketide backbone (PubMed:29142718).  The polyketide synthase module (PKS) of ACE1 is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the tyrosine precursor (PubMed:29142718).  Because ACE1 lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase RAP1 (PubMed:29142718).  Reduction by the hydrolyase ORFZ, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ORF3 then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring enzymes identified within the cluster, including cytochrome P450 monooxygenases CYP1 to CYP4, the FAD-linked oxidoreductase OXR2 and the short-chain dehydrogenase/reductase OXR1, are further required to afford the final cytochalasans that confer avirulence and which have still to be identified (Probable).  The monooxygenase CYP1 has been shown to be a site-selective C-18 hydroxylase whereas the function of CYP3 is the site-selective epoxidation of the C-6/C-7 olefin that is present in some intermediate compounds (PubMed:31644300).  Finally, SYN2 and RAP2 are not required for avirulence in Pi33 resistant rice cultivars (PubMed:18433432).
What are the official names of this protein?
Cytochrome P450 monooxygenase CYP3, ACE1 cytochalasan biosynthesis cluster protein CYP3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS15_PROM9
Sequence: MSLDTAEKQKLIETHQVHATDTGSVEVQVAMLSKRISKLSEHLQGNIHDFASRQGLLKMIGKRKRLLSYIKDKNVQKYQDLVKKIGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.