PharMolix/UniProtQA huggingface dataset:
Protein: LRIG1_HUMAN
Sequence: MARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETVVPPDVPSYLSSQGTLSDRQETVVRTEGGPQANGHIESNGVCPRDASHFPEPDTHSVACRQPKLCAGSAYHKEPWKAMEKAEGTPGPHKMEHGGRVVCSDCNTEVDCYSRGQAFHPQPVSRDSAQPSAPNGPEPGGSDQEHSPHHQCSRTAAGSCPECQGSLYPSNHDRMLTAVKKKPMASLDGKGDSSWTLARLYHPDSTELQPASSLTSGSPERAEAQYLLVSNGHLPKACDASPESTPLTGQLPGKQRVPLLLAPKS
What is the function of this protein?
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
What are the official names of this protein?
Leucine-rich repeats and immunoglobulin-like domains protein 1, LIG-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PELO_METM5
Sequence: MKIIQEIPEKNIIKLIPENLDDLWHLSNIIQPYNAIYAVTERRTEDKGDKLRADRGTKRRVFLGIKAEKINFHEDFNRLRVSGKIIHAPDDIPIGSYHTIDIEPLLQVSVQKNWKKWDLVRLKEAEDSSKKPKVVVVILDDSEADIFLVREFGIKELVSIKSGVSKKLDYKQNEQAKFSYYSDIINSISEFEGKILFAGPGFGKNNIQNYISEKHKDLAPNVVVESANHTGKSGLSEILKSGIIDKIYGEARISKETQVIEKLLEEISKKGLAAYGIESVNNAMNYSAIDTLLLTDEYLRRNRRNIEELMNSVENINGNVLIISTEHDAGKQLKALGGISALLRFPIE
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_LEGPC
Sequence: MHQVIQLKILDSRIGDTIPLPAYATDGSAGLDLRVCISEPMQVAPQQAVLLPTGIAIYIADPKLAAVILPRSGLGHKNGIVLGNLVGLIDSDYQGELKISCWNRSQEHFTVNPGDRIAQLVFIPVVQASFEVVNEFTESSRGEGGFGSSGRY
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS15_HALOH
Sequence: MLTKEEKKAIIEEYQLEEGDTGSPEVQVALLTARIKNLTEHLKEHKHDYHSRRGLLKMVGKRKKLLRYLKRKDINRYRDLINRLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GLMU_RHILO
Sequence: MSQRSCLSVILAAGEGTRMKSALPKVLHQIAGLPMVAHVVKAADAAGASSDAIVIGHGAEEMRKAVTKFSPKAETFVQEERLGTAHAVLAAREAISRGYDDILVMFGDTPLIDAEALNLARLKLAEGAAVAVIGFRPPLPNGYGRLVEKGGKLIAIREEKDCSEAEKKIGFCNAGMMAVAGAHALKLLDAVGNKNAKGEYYLTDIVEIAGAQGLDVVATEASFENALGINNRAELAQAEGIWQARRRQEAMLSGVTLIAPETVYFSHDTEIGADTVVEPNVWFGPGVKIAGGAKIHAFSHIEGATIAANCDVGPFARLRPGADLRNKAKVGNFCEVKQAVIEEGAKVNHLTYIGDARVGAGANIGAGTITCNYDGFSKFFTDIGEGAFVGSNSSLVAPVSIGKGGYIASGSVITESVPDDALAFGRARQKTIPGKGKELRERFASAAAAKKKAAGADH
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_METHJ
Sequence: MNEEIIIDVQGLNLWYGENHALHNVTLPIPNRKVTALIGPSGCGKSTLIRCFNRMNDLVSGCRVTGDILYHGQNINGTGADPVDLRRKIGMVFQKPNPFPKSIYENIAYGPRIHGIKNKRDLDEIVESCLHKAALWEEVKDRLHDSAMSLSGGQQQRLCIARTLAVNPEIILMDEPCSALDPIATSKIEDLIEELKKEYCVIIVTHSMSQASRVSDYTAFMYLGDLIEFGETRQIFENPHKELTENYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PLPHP_DEIRA
Sequence: MSVPAVLAGIREAEAQAGRAAGTVRLVAVTKGHSLDEIRGQVLAHGDFPLAENRGQELRDKVAGLPGAEWHFIGPLQRNKIKYLRGVTLVHSIEEPWQAQAIADAAAEWGQAPAVLLQRHNGEGQKHGVLPDDLPAVLREVRATGLEVRGLMAMAPYDDEARAAQVFADTARQAQDLGLVELSMGMSGDYPLAVAAGATLVRVGRSLFA
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: CAPSD_PMMV2
Sequence: MAYTVSSANQLVYLGSVWADPLELQNLCTSALGNQFQTQQARTTVQQQFSDVWKTIPTATVRFPATGFKRFRYNAVLDSLVSALLGAFDTRNRIIEVENPQNPTTAETLDATMRVDDATVAIRASISPIMNELVRGTGMYNQALFESASGLTWATTP
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: MECA_STRA1
Sequence: MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSELSKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQAEKEVETIGYVHYVFDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDDAISKLQMIEMG
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: EV162_ASFM2
Sequence: MYYPAVQVLIGIILVDNFNTEFLSSEKKNCKTDTDCKDKGHHCVRGTCTDISCLEAVKQDIKDINLDPSIRSCNYTPDFYTFNSTTADLQSPFGKTRIDYGSIYTSDWSSIDHCQSLCCKHNDCIGWEFDKIESSHGGECYFYTNPHPALKNSNDTTIMGIARNIL
What are the official names of this protein?
Putative membrane protein 162.
What is the protein family that this protein belongs to?
Belongs to the asfivirus envelope protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: MOBA_SINFN
Sequence: MVDKTSDSGRCPAVVLAGGRSSRMGSPKAAVLLGGQTMLDRVIERLSPQVASIAVNLNAHSGGALPSGHPAIADTIPGLPGPLAGVLAAMRHARQVAPGASHVLTVPIDAPFFPGTLAARLQGALIVGDEIAVAWSLGEMHPLFALWPLAIADDLDSWIRTDEKRRVRAFIARHASVAVDFPVVATKAGPLDPFLNVNTPQQLEEAEEWLNRLEDSAI
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA1_BRADU
Sequence: MTPPPASAWTRSKPPLLRFLDTCLNEFSAETSGAVADYIPELGNADPAYFGISLATLDGHVYEVGDSRVPFTIQSMSKPFVFALALDLLGAGRVESAIGVEPSGDPFNSIRLNSDNHPFNPMVNAGAIACTGLIYDSKGAEAFEQIRLALSRFAGRDLAVDEAVYSSESQTGDRNRAIGYLLKTNAVISDNVAAVLDVYFRQCAVLVTARDIAVMAATLANRGINPVTGEQVMSAYAISRTLSVMTSSGMYDYAGEWIYRIGIPAKSGVGGGILAALPARLGLGSYSPKLDKHGNSVRGIKVCEALSSHYDLHMLNRSDDARNAVIADYDIGKSPSRRVRRAQEREILAAHEQEVRIIELVGTLSLSAVDYVSRRLAGRPRPQFVIFDLHRVTSTTRAGARLVAEAFEELAALNVTVVLSGVRRASKEWNTLREWTAELKNVRDFYLLDTAIEWAEDQIVYRYGGSIDFHETTELAEQPLLEGLSADELAELGAICTIRTYQSGAKILTTGDPADALFFLRSGAVHVTLPDGVRLATLTAGMAFGEMALLEQTRSADVFADMAATAFEAPLKDFERFREQHPRASERIMRNLAQLLADRLIVANAKVDILTST
What are the official names of this protein?
Glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: SPRT_SALTI
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_BACAN
Sequence: MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDHAVAVNMLLKKLTENGIVKSLDEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPLHNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLYSLPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPYIMEKTGQTVEEVVSVLNKKSGMLGLTGYSSDLRDIIAKEEEGDHRAKVALDVFVSRIHKYIGSYTARMKGVDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVFGEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGNIG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_RICRS
Sequence: MSKIPSVNIKALLDAGVHFGHKTSRWNPKMASYIYGKRDDVHIIDLRQSVALMNVALNAIYETVKKDGKILFVSTKIQASDIIAEYAEKCGQYYVNHRWLGGMLTNWKTIAGSIEKLNKLDKTLENEEALMGYTKKEILDMSRKKDKLLLSLAGIRNLNSKPDLLVVIDTNKEHIAINEAVKLNVPIVAVVDTNSNPDNVDYPIPGNDDSIRSIRLYCSLFADAALQGLEESMKASGVDMGAMQEHTDKGLTSKNVSKLKQAKKFSKTKNIDEETNTEFEQVLNDADENKNSDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ANO3_HUMAN
Sequence: MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHATYDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQQRRKSGQPVHHEWP
What is the function of this protein?
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (By similarity).  Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity).  Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:21984732).
What are the official names of this protein?
Anoctamin-3, Transmembrane protein 16C.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization.
Protein: Y1289_PSEPK
Sequence: MLTVISPAKTLDYDTPPVTERFTLPQYLDESQALIQQLRELSPAQISELMHLSDKLAGLNAARFGSWTPDFTPANAKQALLAFKGDVYTGLDAESLSEDDFSYAQGHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANARGKDLYAFWGTRISEWLNQALADQGDDVLLNLASNEYFSAVKRSALKARVINVDFKDQKNGQYKIISFYAKKARGMMSRFVIQQRISTPEQLKQFDAQGYYYSAEQSKPDHLVFLRDHPAE
What are the official names of this protein?
UPF0246 protein PP_1289.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: HMUV_BORAV
Sequence: MTLQAQDLSVDRGAKRILTQVSLTLEPGRMLGLLGANGAGKSTLLACLSGELEPVCGHIEINGKPLRSLASAKQARLRAVLPQKPSLSFDLGVREVVGMGAYPYAELSPADVDALCEKALRQAGVSHLAGRRYLELSGGEQQRVQFARVLMQCQAAPAGQPRYLMLDEPISNLDPRHQIDVLRTAHDLAREAGVGVLVIVHDVNLSARWCDRLLLLAQGSVVADGAPAEVLTPANLRRVYGVEADVLPHPREAGTLLVLMR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: F246A_HUMAN
Sequence: MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGQEDARAPGRLARLLGQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRATPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPVRKNHKKMPVPPGAPQGGGD
What are the official names of this protein?
Protein FAM246A.
What is the protein family that this protein belongs to?
Belongs to the FAM246 family.
Protein: CAAT6_ARATH
Sequence: MEVQSSSNNGGHSSFSSLRVYLNSLSATPSRLSRRAISVSTSSDEMSRVRAVSGEQMRRTLRWYDLIGLGIGGMVGAGVFVTTGRASRLDAGPSIVVSYAIAGLCALLSAFCYTEFAVHLPVAGGAFSYIRITFGEFPAFFTGANLVMDYVMSNAAVSRSFTAYLGTAFGISTSKWRFVVSGLPKGFNEIDPVAVLVVLVITVIICCSTRESSKVNMIMTAFHIAFIFFVIVMGFIKGDSKNLSSPANPEHPSGFFPFGAAGVFNGAAMVYLSYIGYDAVSTMAEEVENPVKDIPVGVSGSVAIVTVLYCLMAVSMSMLLPYDLIDPEAPFSAAFRGSNGWEWVTKVVGIGASFGILTSLLVAMLGQARYMCVIGRSRVVPFWFAKIHPKTSTPVNASTFLGIFTAALALFTDLNVLLNLVSIGTLFVFYMVANALIFRRYVPVGPTKPWPTLCFLTLFSITSLVFTLIWKLVPEGKPKAFMLGASAVVAIAIVLSFQCVVPQARKPELWGVPFMPWTPCVSIFLNIFLLGSLDAPSYVRFGFFSGLIVLVYLFYGVHASSDAEANGSFGVKDGQVMKELIEV
What is the function of this protein?
Permease involved in the transport of the cationic neutral or acidic amino acids.
What are the official names of this protein?
Cationic amino acid transporter 6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: SYP_THEPD
Sequence: MSEQGITVSKSEDFSEWYSQVLSKAGLVDLRYNVQGFVVHKPWLMRIIKAIYRFFEEELEKTGHEPVLFPLVIPEENFEKEKEHVEGFKPEVFWVTQAGDEKLERRLALRPTSETAFYYMYSYWIQSWRDLPLKLYQSVSVYRNEKNTRPLIRGREFLWIEAHDAFATHEEALNQIREDMENSRKVIWEKLGIPFLFLRRPPWDKFSGAEDTYAADTIMPDGRVLQISSTHDLGQRFAKAFNVTFLDKDGKRKYVWQTCYGPGIWRITAALIAIHGDDKGLVLPMNVAPIQVVIVPIYYKESDKERVLEKCRKLEAMIREAGYRVYLDAREEYTPGWKFNDWELKGVPVRLEVGVREVETGTVTVFRRDLRVKEKVADSELISHIRKLENDILEELKRRAKEFFESRIVTATRREEVEEALRSGKMVKMPFCGREECADDLKEATDGGKVRGTEIDFKEGDYGRCAWCGAPARLIVYVAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCP9_SCHPO
Sequence: MATTNKVYFIAGGNRGIGLSLVKELSSREGTTVFASARKPEAATELQEWSKSHPNVKTVELDVTSQQSANEAAQSVAKAVDGIDVLWLNSGICQSYYTVMEAPEEVWNAHYQTNVLGPIHVFKAFYPLLTKKKTRQVIFTSSECGSMGDFRATGFSAYGQSKAAINFTMKELSVELADEHFTFISIHPGVVKTDMNADAIKKFTETSPEMLTYLKKVTIIPEESVSSMLKVVDNLKPENNGSFYRYDGTIIPF
What are the official names of this protein?
Uncharacterized oxidoreductase C663.09c.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DUO1_ARATH
Sequence: MRKMEAKKEEIKKGPWKAEEDEVLINHVKRYGPRDWSSIRSKGLLQRTGKSCRLRWVNKLRPNLKNGCKFSADEERTVIELQSEFGNKWARIATYLPGRTDNDVKNFWSSRQKRLARILHNSSDASSSSFNPKSSSSHRLKGKNVKPIRQSSQGFGLVEEEVTVSSSCSQMVPYSSDQVGDEVLRLPDLGVKLEHQPFAFGTDLVLAEYSDSQNDANQQAISPFSPESRELLARLDDPFYYDILGPADSSEPLFALPQPFFEPSPVPRRCRHVSKDEEADVFLDDFPADMFDQVDPIPSP
What is the function of this protein?
Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328).  Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e. g.  MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502).  Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502).  Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252).
What are the official names of this protein?
Transcription factor DUO1, Myb-related protein 125, AtMYB125, Protein DUO POLLEN 1.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in sperm-cell nuclei.
Protein: ENO_SHEB9
Sequence: MAKIINVIGREIMDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRYLGKGVLTAVANVNDLIRTALLGKDATAQAELDQIMIDLDGTENKDKLGANAILAVSLAAAKAAAAFKGIPLYAHIAELNGTPGQYSMPVPMMNILNGGEHADNNVDIQEFMVQPVGAKTFREALRMGAEIFHTLKKVLHDKGLSTSVGDEGGFAPNLASNADALAIIKEAVELAGYKLGTDVTLALDCAASEFYKDGKYDLAGEGKVFDSNGFSDFLKSLADQYPIVSIEDGLDESDWDGWAYQTQIMGDKIQLVGDDLFVTNTKILTRGIENGIANSILIKFNQIGSLTETLAAIRMAKEAGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEQLGEKAPYRGLKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: NCAP_CVBLS
Sequence: MSFTPGKQSSSRASSGNRSGNGILKWADQSDQSRNVQTRGRRAQPKQTATSQQPSAGNVVPYYSWFSGITQFQKGKEFEFAEGQGVPIAPGVPATEAKGYWYRHNRRSFKTADGNQRQLLPRWYFYYLGTGPHAKDQYGTDIDGVFWVASNQADVNTPADILDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSAPNSRSTSRTSSRASSAGSRSRANSGNRTPTSGVTPDMADQIASLVLAKLGKDATKPQQVTKQTAKEIRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGGEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNLDEPQKDVYELRYNGAIRFDSTLSGFETIMKVLNENLNAYQQQDGMMNMSPKPQRQRGQKNGQGENDNISVAAPKSRVQQNKSRELTAEDISLLKKMDEPFTEDTSEI
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: TVB23_HUMAN
Sequence: MGTRLLGCAALCLLAADSFHAKVTQTPGHLVKGKGQKTKMDCTPEKGHTFVYWYQQNQNKEFMLLISFQNEQVLQETEMHKKRFSSQCPKNAPCSLAILSSEPGDTALYLCASSQ
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
Probable non-functional T cell receptor beta variable 23-1.
What are the subcellular locations of this protein?
Cell membrane.