PharMolix/UniProtQA huggingface dataset:
Protein: COAD_THEFY
Sequence: MRRVVCPGSFDPVTNGHIDIIRRAAKQNEEVIVAVLVNVNKRGLFTADEKLEMLREATKEFDNVTVAKFDGLLVDFCRAHDVSAIVRSLRSVSDFDYELQIAQMNYQLSGIDTLFLTANPKYSFLSSSLVREIAQYNGDVSALVPPYVEERLRAKYAELAKKNG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y786_RICPR
Sequence: MSWIIFYTIIAALLILDLGIIHKKNKVISFKGSILLSLFYFIISCLFGIYVYHNMGLDHAREYYTCFLIEKAMALDNIFIISIIFQFFNIPSTYQHRVLFFGIIGVIIFKAIIIYGGIMLIHKFSWLLYILAVILIATGIKTFNVSHKTYDIQNSYIYKSIIKNLNITHDLEGQKFVIKRNNKLYFSTLFVSLILIETIDLVFAIDSIAAIFAITNDVYIIYTSNIFAILGLRSLFFCLSEIVERFSYIKYSLALILIFIGFKIFIHHYIEIPAYISLTVTISSLLFGIIASILEKI
What are the official names of this protein?
Uncharacterized membrane protein RP786.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: REM9_ARATH
Sequence: MANASPLSPTNQHFFQPLLPGFQSNLKIPVNYFSEHIEGKHEGKTVTLRTDASERTWEVKMEGHRLTEGWKEFVEAHDLRIGDFVVFRHEGDMVFHVTALGPSCCEIQYPQSSRHEEGEESGENEISEKEGEENVQKESDKSSSDLNCFSQSVTHSNISRDAVSVPRDFVKRSGFSKGRHEIVLMNEEGKSWESEVKSYMSGAVYLVGGWTTFCTENKLDVGDSCTFKLLQKAKTPVFQLCSRTKHLPLSFTKVNGLINPGKIILVDKDRAEWSMMLKVDSRGAVYIIGGNDWKSFCAANEVGAGESLALELIQGGVLLNQITTCFQMEQPSFKAEDGRHKRARVQNRSQETDKGAETSRASTMGPKLEITEKGEPSRASTMRPKVEIREKIAETGEPSRASNKSSGIEGNLQHTKPCSVKTDQLAKVKESVVDTLTSIGRFQAELETMKRKLEDSLQELN
What are the official names of this protein?
B3 domain-containing protein REM9, Auxin response factor 23, Protein REPRODUCTIVE MERISTEM 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_SERP5
Sequence: MNLISIPAFQDNYIWLLDNQQGHCIIVDPGEAQPVLETLDRLNLTPDAIVLTHHHHDHVGGVAQIVARYSGLKVYGPQETADKGANHIVHDGETIEINGQKFATIAVPGHTLGHVAFYSAPYLFCGDTIFSAGCGRLFEGTAEQMFNSFQQLAQLPDNTLICCAHEYTLSNLKFARAILPKDRHIETYQQQVEALRAKGQSSVPTTLQLERKINLFLRCHDTDLQRELGFHTPPEHLHSVFSELRLRKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GRPE_BURO1
Sequence: MENTQENPTTPSAEDIGSEKQAAQGAAPAAEAADAALAEAQAKVAELQESFLRAKAETENVRRRAQDDVSKAHKFAIESFAEHLLPVLDSLEAAVNDTSGDIAKVREGVELTLRQLTSALEKGRVVAINPIGEKFDPHQHQAISMVPAEQEPNTVVSVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
Protein: MSCL_YERPE
Sequence: MSFMKEFREFAMRGNVVDLAVGVIIGAAFGRIVSSLVADIIMPPLGLLLGGVDFKQFHFVLRAAEGTIPAVVMNYGTFIQSIFDFVIVALAIFSAVKLMNKLRREKAEEEPATPPAPTTEEILLAEIRDLLKAQHTK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRX2E_ARATH
Sequence: MATSLSVSRFMSSSATVISVAKPLLSPTVSFTAPLSFTRSLAPNLSLKFRNRRTNSASATTRSFATTPVTASISVGDKLPDSTLSYLDPSTGDVKTVTVSSLTAGKKTILFAVPGAFTPTCSQKHVPGFVSKAGELRSKGIDVIACISVNDAFVMEAWRKDLGINDEVMLLSDGNGEFTGKLGVELDLRDKPVGLGVRSRRYAILADDGVVKVLNLEEGGAFTNSSAEDMLKAL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides (By similarity).  May be involved in chloroplast redox homeostasis (Probable).
What are the official names of this protein?
Peroxiredoxin-2E, chloroplastic, Glutaredoxin-dependent peroxiredoxin, Peroxiredoxin IIE, Thioredoxin peroxidase 2E.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: LEUC_STRAW
Sequence: MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIATEDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTAKDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTFAYLKGRAHAPEGEEWDAAVAYWKTLKSDEDAEFDAEVVIAAAALSPFVTWGTNPGQGAPLSASVPDPASYEDASERFAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAAIVEGRKVADGVRMLIVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLADENAARTPAGV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PYRI_ENT38
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLTLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTDEQVNQLSLYAPDATVNRIDDYEVVGKSRPNLPERIDTVLVCPNSNCISHAEPVSSSFAVKKREKDIALKCKYCEKEFSHYVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: SUCD_ECO57
Sequence: MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
Protein: BUK_BACTN
Sequence: MKILVINPGSTSTKIAVYENETPLLVRNIKHTVEELSVYPQVIDQFEFRKNLVLQELEANGIPFAFDAVIGRGGLVKPIPGGVYAVNEAMKQDTLHAMRTHACNLGGLIAAELAASLPDCPAFIADPGVVDELEDVARISGSPLMPKITIWHALNQKAIARRFAKEQGTKYEELDLIICHLGGGISIAVHQHGKAIDANNALDGEGPFSPERAGTLPAGQLIDICYSGQFTKDELKKRISGRAGLTAHLGTTDVPAIIKAIEEGDKKAELILDAMIYNVAKAIGGAATVLCGKVDAILLTGGIAYSDYIISRLKKRISFLAPIHVYPGEGEMESLAFNALGALRGELPVQIYK
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT21_YEAST
Sequence: MSELSQMTLKILYTLDNGSNGSYLARSRAPKQVRVANIPSPFPTDSNEQTELRIGAIHLKTILHEIYLNSPEVLDHDTLKDGYDYNLYYRDICEVDEPLVSLGLLSGLRKKFHKNSPYQYTENNIGEEESEERDEVTEEEYEDESFIVTGRVCSNVSALLRRSYSNISNKKGRVVNNQIPEETLEVKLRFTKVITNLRTSGNNTTNSRISCLQMPSSLPSATLPFTPKSQSLFKTNQIKNSRNARTTITINNTNSGTVGRRQTNPMPAPKAVRTQSLPIWNLKPNIANTGFPRNSIAHKIYLADRKTEANQQNNQHQNIAYEINTLQNDNTIQRTKIDDSVSKRFDFMLNKRKSTKKVSPGIATIAKKPASININPKQPPKTSGEKKANDKQTIVKVKNSNSKNSAKSTQAGCRRSSVIEHLNDHDDSILSDILSEPGIEGQKLQQKQKGRKISLTSENDKENIPPQSITSKENKLEGDLDFNAEFPMSDFSDVVFKDEMGWFSNFNCNFFESPTSASASQLNQQNLKPSITLNDPNTCNTIALENEDVSELETAQNNKISLPSDVDKTSPIDSLSIPLIELTHSSSTTNMQRISIKEGSTLNITDSNNATPCDNDIKDRKASVIDSDNTKPQAGLINFSTPADQPASDNNVTASKKLTSMLETQQSKRSHEEVLDEEEEEEALKKQKAIPSSPCGMFNYHQPMELSEDIVEEEQGHNIGDDNESDKTNDLFSTFIHSGIRVSQVVTSPIGEFQSIKH
What is the function of this protein?
Required for normal transcription at a number of loci in yeast.
What are the official names of this protein?
Protein SPT21.
Protein: G6PI1_CHRSD
Sequence: MFQLTRSVTWRALERLKQETFDDRISDYFAADPQRFEKMSLRVGGLFLDYSKHHVSDAVLAKLIELADHSALVQRRAQMFSGDIINVTEDRPVLHTALRHLGDEPVYADGKDVMPEIQSTREQIKRFSEAVRSGEWKGYSGERIKDVVNIGIGGSDLGPNMACRALLKYRHPELNFHFVSNVDGTHIQKVLQRLDPATTLFIVSTKTFSTQETLLNAKTARRWFLDNAGEDADVGAHFIAASTNRKAAMEFGIREENVFEFWAWVGGRYSMWSSIGLPIALSIGFDGFMELLEGAHEMDRHFIEAPFAENMPVLMALIGIWYINFIGAETHAIVPYDQALHQLPSFLQQLDMESNGKSVDIFDQPVNYKTGPIVWGQTGSNGQHAFFQLLHQGTRYVPIDFIASLKPEPGFEDHHFALLTNMLAQANAFMEGSQDGSQLDPYSCPGNRPSSTLLLDELTPRNLGALIALYEHKVFVQGVIWNINSFDQWGVQLGKRIAGEISERIDTNVGDFDASTQGLLSLVREYFPASTPDAKASDNNKKSRGKTS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_STAAB
Sequence: MVHNKNNTILKMIKGEETTHTPVWFMRQAGRSQPEYRKLKEKYSLFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPIKTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMFRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYRRYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQLGVTKTLQGNLDPSILLAPWNVIEERLKPILDQGMENGKHIFNLGHGVFPEVHPETLRKVSEFVHTYTQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_LIMRJ
Sequence: MARVTTQFTGIIMYRQDYRERDLLVKMLTDKIGPAMFFVKNAKKRGFRMTADILPFTHGTYIGSLDENGLSFINTASDTSQYKKIASDISKNAYVTYILALVDSAFNDGRSIGGWFKQVAAALDLIEKGLDEQIITNVIETQLLVAFGVAPVWDRCVVCGRNDLALDFSEQYGGMLCQNHWSLDEHRLYLDRKTAYYLQQFATINLQKLNSIRINPATKRRLQQVLDTLYDNEVGLNLKAKRFIKQMNKWEQNIGKLSMND
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS17_BORA1
Sequence: MSETQNTQVTKRQRTLVGKVVSNKMDKTVVVLVERRVKHPIYGKIVMRSAKYKAHDESNQYNEGDTVEIAEGRPISRSKAWRVVRLVEAARII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS13_PYRAR
Sequence: MSQELRAIVRVGDTDLEGNKQVAYALAKIRGIGIASAYAICWKLGIDPHAVLGALPEEQINKLDWAVRNLHEVAPAWFLNRRKDPETGRDMHLIGSELVLAAKRDVDLMKKLKSWKGIRHSLGLKVRGQRTVTTGRLGAVAGVTKKKATPGK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DHAR_ECOLI
Sequence: MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFASIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSALGFNDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQVLWNWAFCATPLFDSKGRLTGTIALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVISWDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFESQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAALAEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQFKRRV
What is the function of this protein?
Positively regulates the dhaKLM operon from a sigma-70 promoter.  Represses its own expression.
What are the official names of this protein?
PTS-dependent dihydroxyacetone kinase operon regulatory protein.
Protein: RS13_RHOPA
Sequence: MTGEKSVARIAGVNIPTNKRVLIALQYIHGIGQKNAADILEKVKIPLDRRVNQLSDAEVLQIREVIDRDYLVEGDLRRETGMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13, RRP-S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: UCH3_ARATH
Sequence: MATASESSSSKRWLPLESNPDVMNQYLWGLGLAPDEAECNDVYGLDDELLEMVPKPVLAVLFLYPITKKSEEERIEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNITSEIKLSDGSFLDRFFKSTANMTPMERAKFLENDSQIEDAHSVAVIAGDTPASEDADTHFICLACVEGELYELDGRKAGPISHGASSPATLLKDATKVIKKMIEKNPGSLNFNLIAISKRT
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
Protein: PNS1_CANAL
Sequence: MSDYPPPNYPPPNHPQYQQQQDETYHVRPDMERQQDFGYYEKPTPSQNFDDSFKVEKPKFNDWPFAIFFWLVVAGFIAVAGITLNALRSTYGFQGGSIYGSGNTFTLNTNTIILFAFIIVMAFILSAAIIVFARLAPKAFIVTGVILNVVLGIGTAIFYFVEKYYSAAIVFLIFALFGAWCYWSSRHRIPLSATILTIVIDVMKMYPSTLIASFIGLIFSAAFSALFSIVIVATYVKYDPNSNNEACSVGGGSCSKGKLIGVLVFVFFAGYYISEVIRNVIHVVIAGIYGTWYYLANSDQGAPKHPALSSLKRALTYCFGSITFGSLIVSLIQLLRQFISILRSNFAADGNGWGVCGMIILDFFVGFIDWLVRYLNKYAYCYVALYGKSYIKSAKDTFDLIRFKGMDALINDMFINTALNLYSLFVAYLVALLAYLYLKFTKPEYNSGGAFYAPVIAFAFLIAGQINRISLTVIESGTATFFVALAKDPEIFQMTNRNRFDDIFRNYPQVLEKITSDH
What is the function of this protein?
Probably involved in transport through the plasma membrane.
What are the official names of this protein?
Protein PNS1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTF_RHYMA
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic hormone, HTH, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: THB_CHICK
Sequence: MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYEGKCVIDKVTRNQCQECRFKKCIFVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKTIGHKPEPTDEEWELIKIVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLVCVERIEKCQEGFLLAFEHYINYRKHHVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_ACIAD
Sequence: MSNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVKAGDKVLFGTYAGTTVKVNGEEFLIMKESDILAVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_SALPB
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_HALOH
Sequence: MKIKNPRFVISAYDFDDFPTHNWPEFAFSGRSNVGKSSLINTLVNRRKLARTSSRPGRTQSINFFNIDDRFYLVDLPGYGFANVPRKVKEEWGRLIEGYLNNRPNLAGIVQIVDARHKPTRDDLMMVDWIKASGIPCLIAATKVDKISRGSRKKQEELIKKTLVLEDFDGQFTFFSAKTGEGKKQVGKFILDLVDSFKG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: BAH2_NOCSJ
Sequence: MTRPIEVRKVPIEHVSDAAGLADLIDAGVFSADDVIAVVGKTEGNGGVNDYTRIISTHAYRAVLEEKGTRSKEEVAQVPLVWSGGTDGVISPHATIFAYAPEGRYLPTDEPRVTVGYAMSEVLLPEDIGRPAMVEKVAAGVRVAMERAGITDPADVHYVQTKTPLLVQDTINDAERRGETVYTHNTLESMDVSNATTALGIAVALGEIEMPTAEQIFHDLSLYSSVASCSSGVELDQAQIVVVGNARGVGGRFRVGHSIMKDALDMDGVWAAIRDAGLDDMPVDCIHPRHIKGRLVNLFLKCEADPTGRVRGRRNIMLDDSDVAWHRQIKACVGGVVAAVSGDPMNFVSVAAVHQGPSGGGPVIAIVDLEA
What is the function of this protein?
Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines.  Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid.  Can also use cyanuric acid as a substrate, albeit with lower efficiency.
What are the official names of this protein?
Barbiturase 2, Barbituric acid hydrolase 2, BAH 2.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: CYL2_ORYSJ
Sequence: MAHLATVVLLLVAAARQAPLAAGDHSANPRLPTCAAAPDVAAPQEHGDGGGVGGGRRILDITHAVRAELPVLGSCDGVGALVRLKKSMANGSRSNLSELRMSVHTGTHVDAPGHMWQPHFDAGLDVDTLDLGLLNGPALLVDVPRHSNVTAEVMESLNIPRGVRRVLFRTMNTDKRLMWQKESDLSFVGFTEDGAQWLVGYTDIKLVGVDYLSVASYEHMIPAHVVFLKSKEIVIVEALKLDDVEPGMYMLHCLPLRLAGAEGSPVRCILIK
What is the function of this protein?
May be involved in response to stresses.
What are the official names of this protein?
Cyclase-like protein 2, OsCYL2.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: OTCC_STRP8
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGPC_CERS4
Sequence: MAEISLRDVRKSYAGIEVIHGVDFEIADGEFVVIVGPSGCGKSTLLRMVAGLEEITAGEIAIGGRVVNRLEPRERDIAMVFQNYALYPHMTVRENMAYGLRIAKLSKAEIEERVARSATMLELGQLLDRKPRQLSGGQRQRVAMGRALVRNPAAFLLDEPLSNLDAKLRVQMRLQIKELQRTVRTTSIYVTHDQVEAMTLADRLVVMNAGVAEQIATPAEIYDRPATTFVAGFIGSPAMNMLPARGLGDALEVAGQRLAVPAPAGRDLILGVRPEHLHAAGPEEPGFELHVQAVEWLGADAFAHGRLADGTELVLRTPGKAPVRERDRLKVAPDAAALHLFDAETGRRL
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPF_THEP1
Sequence: MGFLEINWTSAAMLMLFVLMVYFLNKFLYTPFIEMAEKRRKKVEEDLKSAEQLKEEAEKMRSEAERFLSEARQRADEIVESARKEAEAIVEEAREKAKKEAQNIVESAKTQIEVEYKKALEQVQERAAELSVILATKLLQKVFQDERARREYLVKILKEEIEKS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: THTR_HUMAN
Sequence: MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
What is the function of this protein?
Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes.  Other thiol compounds, besides cyanide, can act as sulfur ion acceptors.  Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity).  Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA.  Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.
What are the official names of this protein?
Thiosulfate sulfurtransferase, Rhodanese.
What are the subcellular locations of this protein?
Mitochondrion matrix.