PharMolix/UniProtQA huggingface dataset:
Protein: FEN1_UNCRE
Sequence: MGIKHLYQIISENAPDAVKSGEIKNQFGRKVAIDASMSIYSFLIAVRSDGQQLMNESGETTSHLMGLFYRTLRMVDNGIKPLYVFDGAPPKLKSGELAKRIARKQEAAEQHEEAKETGTTEDVEKFSRRTVRVTREHNEECKKLLKLMGIPYINAPTEAEAQCAVLARAGKVYAAASEDMDTLCFDSPILLRHLTFSEQRKEPILEIHLDRVLEGLGMDRKTFVDLCILLGCDYLDPIPKVGPNTALKLIRDHGSLEKVVEAMKNDPKQKYTIPDDWPYEQARDLFFEPDVRPADHPECDFKWEAPDVEGLVKFLVEGKGFSEDRVRSGAARLQKNMKTAQQSRLEGFFKPVAKTDEEKASLKRKHEEKLEAAKKKKKEDAKAKREAKSRPKGTA
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: MAPC3_ARATH
Sequence: MESSKPKNRNPMKKPVSITMEHVLLALRETMDEREIRIRSLFDFFDNSNLGFLDYAQIEKGLASLQIPPEYKYARDLFRVCDANRDGRVDYQEFRRYIDAKELELYRIFQAIDVEHNGCILPEELWEALVKAGIEIDDEELARFVEHVDKDNNGTITFEEWRDFLLLYPHEATLENIYHHWERVCLIDIGEQAVIPDGISKHVKRSRLLLAGGLAGAVSRTATAPLDRLKVVLQVQRAHAGVLPTIKKIWREDKLMGFFRGNGLNVMKVAPESAIKFCAYEMLKPMIGGEDGDIGTSGRLMAGGMAGALAQTAIYPMDLVKTRLQTCVSEGGKAPKLWKLTKDIWVREGPRAFYKGLFPSLLGIVPYAGIDLAAYETLKDLSRTYILQDTEPGPLIQLSCGMTSGALGASCVYPLQVVRTRMQADSSKTTMKQEFMNTMKGEGLRGFYRGLLPNLLKVVPAASITYIVYEAMKKNMALD
What is the function of this protein?
Calcium-dependent mitochondrial carrier protein that catalyzes the import of ATP co-transported with metal divalent cations across the mitochondrial inner membrane in exchange for phosphate (Pi) (PubMed:22062157, PubMed:28695448, PubMed:26140942, PubMed:26444389).  Can transport phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate, sulfate and thiosulfate, and, to a lesser extent, other nucleotides (PubMed:26140942, PubMed:26444389).  Binds calcium ions Ca(2+) (PubMed:22062157).  Mediates also calcium uptake (By similarity).
What are the official names of this protein?
Calcium-dependent mitochondrial ATP-magnesium/phosphate carrier protein 3, AtAPC3, Mitochondrial ATP-Mg/Pi carrier protein 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MROH8_HUMAN
Sequence: MSSKHRICSQEEVVIPCAYDSDSESVDLELSNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAYVAVAVSP
What are the official names of this protein?
Protein MROH8, Maestro heat-like repeat-containing protein family member 8.
Protein: RS8_RICB8
Sequence: MSMTDNVADMLTRIRNAYKSKLINVSFPSSKIKTSILEVLQKEGYIKNYTSTPKDNISYTEVTLKYSANGDASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYILSTPYGVMSDREAHIKNVGGEVICKVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DPHB_NATPD
Sequence: MLTFVGLGLYDERSITVAGREALRSADRVFAEFYTSKLAGATVEELQNHHDIDIEVRDRAGVEQEPGPILDAAEAGGAVFLTAGDTMISTTHVDLRLRADNRGIETQIIHGTTAGAAAASLSGLQNYRFGKATTLPFPYAHGGEGVPGSVLDTIADNRKRGLHTLVYLDIKVGTGPRGPDPDHEEYMTADYAAELLAEDLDTVGVAIARAGSPDPVLAADRLSALADRSFGDPLHLLIVPGDLHVVEHDALVALAGAPESALPDPV
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: OTC_LEPIN
Sequence: MSESNVKHLISWEDWSDSEILDLLDFAIHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASNFQLSDIDLEARYLSRNVSVIMARLKKHEDLLTMRNGSQVPLINGCDNMFHPCQSLADIMTIALDKPEIPLNQIQLTYIGVHNNVVNSLIGITSALGIRLTLVTPIAEKENIHSQTVERAKAKGTLSWEENLKKAIQNADYVYTDTWLDMEFFNDPSYADKKKQRMELMMPYQINSSLLEKTNAKVMHDMPIHAGYEITREVVLGPRSIIFQQAENRLDAQKAVILKLLEA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_GEOSL
Sequence: MIRHFLALNQFTKEELDGLFTLSRELKDKQKQGVPHRLLEGKSVALIFEKSSTRTRVSFEVGVAQLGAHPLFISSATSQMGRGEPIKDTARVMARYCDGVMIRTYGQEIVEEFARYSSVPVINGLTDLFHPCQIMADLFTVIEYKGGYQGLKFAWVGDGNNMANTWIEAAAILGFDLALACPTGYEPDRQVWDWAQQRATSSITITEDPEEAVRDADVVNTDVWASMGQEQEQKEREAAFQGYCLDDALVALARPDCMVLHCLPAHRGEEITDSVIEGPRSAVWDEAENRLHIQKAIMASLMK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBG1_BOVIN
Sequence: MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDIFKENFDELDTSREIVQQLIDEYHAATRPDYISWGTQEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.  Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
What are the official names of this protein?
Tubulin gamma-1 chain, Gamma-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to mitotic spindle microtubules.
Protein: AIS_ECO27
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: OBG_CLOB8
Sequence: MFIDTAKVFVKSGNGGNGAISFRREKYVPLGGPDGGDGGKGGSIIFQVETGITTLLDFKYKKKFIAESGENGGGSKCYGKDGESLYIKVPMGTIIREAETNKIIADLSHKGQELVLLRGGKGGKGNVKFATATKQAPHYAEPGMPGDELNIVLELKLLADVGLLGFPNVGKSTLLSMTTKAKPKIANYHFTTLKPNLGVVAVDGIDPFVMADIPGIIEGAAEGVGLGIQFLRHIERTRLLIHIVDISGVEGRDPFEDFIKINEELKKYSVKLWDRPQIVVANKSDMLYDEGIFEDFKKKVQEMGFDKVFKMSAATNEGVDAVMKEAARILKDIPVKELEISEDEMYIPEEKRFTYDITVEHNKEEGYDVYIVEGTFVDRLLSAVNVNDADSLRYFHKVLRNKGIFDELREMGVKDGDMVRLNDFEFEYIL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_JANMA
Sequence: MKPVIALIGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGFEPVAKEGIMHEMAKQTKQAVAEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNKAEGMKYTTVTADFYELGMGDPYVISAAHGDGVNDLVEEALNIAFAQRPPEEEAPASNDRSIKLAIVGRPNVGKSTLVNTLLGEERVIAFDLPGTTRDSIEIPFERDGKHYTLIDTAGIRRRGKVFEAIEKFSVVKTLQSISEANVVLLLLDAQQDISEQDAHIAGFILESGRALVVGVNKWDGLTSDRRDEIKMDLERKLSFLSFAKTHFVSALKSSGIGPMMKSVDGAYAAAMSNLSTPKLTRALIEAVEHQQPRRKGSIRPKLRYAHQGGMNPPIVVIHGNALEAIDANYKRFLEKHFRETFSLVGTPLRIELRSGKNPFSRSEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: FEMX_STAAC
Sequence: MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKTYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
What is the function of this protein?
Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (GlcNAc-(beta-1,4)-N-acetylmuramic acid(-L-Ala-D-iGln-L-Lys-D-Ala-D-Ala)-pyrophosphoryl-undecaprenol), using glycyl-tRNA(Gly) as donor, in a ribosome-independent mechanism.  Involved in methicillin resistance (By similarity).
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STRGG
Sequence: MSSTEPDALLGPADIRDLAATLGVRPTKQRGQNFVIDANTVRRIVRTAEVRPDDTVVEVGPGLGSLTLALLEAADRVVAVEIDDVLAAALPATVQARMPERADRFALVHSDAMLVTELPGPAPTALVANLPYNVAVPVLLTMLERFPSIERTLVMVQSEVADRLAARPGNKVYGVPSVKANWYADVKRAGAIGRNVFWPAPNVDSGLVSLVRRTEPIATTASRAEVFAVVDAAFAQRRKTLRAALSGWAGSAPAAEAALVAAGISPQARGEALTVEEFAAIAEHKPEVSSL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_BACCQ
Sequence: MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSVLLKEKVVGTDPEKVGLEAADRLINQGAKELILAANKEQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: DHE3_ARATH
Sequence: MNALAATNRNFKLASRLLGLDSKLEKSLLIPFREIKVECTIPKDDGTLASFVGFRVQHDNARGPMKGGIRYHPEVEPDEVNALAQLMTWKTAVAKIPYGGAKGGIGCDPSELSLSELERLTRVFTQKIHDLIGIHTDVPAPDMGTGPQTMAWILDEYSKFHGHSPAVVTGKPIDLGGSLGRDAATGRGVLFATEALLNEHGKTISGQRFAIQGFGNVGSWAAKLISDKGGKIVAVSDVTGAIKNNNGIDILSLLEHAEENRGIKGFDGADSIDPDSILVEDCDILVPAALGGVINRENANEIKAKFIIEGANHPTDPEADEILKKKGVMILPDIYANSGGVTVSYFEWVQNIQGFMWDEEKVNRELKTYMTRGFKDLKEMCQTHSCDLRMGAFTLGINRVAQATTIRGWGS
What are the official names of this protein?
Probable glutamate dehydrogenase 3, GDH 3.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: CLPC_MYCLE
Sequence: MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLDSLGISLEAVRSQVEDIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGNWTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKVKDMTLELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVVTVDVDNWDGEGPGEDVKFTFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ
What are the official names of this protein?
Probable ATP-dependent Clp protease ATP-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: MAMB4_DENVI
Sequence: RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYGGCRGNGNRFRTIEECRRTCVG
What is the function of this protein?
Interacts with vasopressin V2 receptor (V2R/AVPR2), probably in a selective manner.  Inhibits vasopressin binding human V2R in the nanomolar range (Ki=7. 34 nM), and also potently inhibits vasopressin-induced cAMP production (IC(50)=26 nM).  In vivo, intraperitoneal injection of this protein into rats increases diuresis by 8. 6-fold, without any loss of electrolytes.
What are the official names of this protein?
Mambaquaretin-4, MQ4, Upsilon-Dv2c.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
Protein: BTBD6_XENTR
Sequence: MPLDPGCLNGRVMKCLTFFLLLPETLKKSRKSARAQGKVQACYEIVPLALKKKMAAELYPASANTNIANSNAAANAKKNALQLQQAAPPPPQLHNLNNNNIESGNWQSFHPTLRERNALMFNNELMADVHFIVGPAGASKKVPVHKYILAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLKYLYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPDLTLRCWEVIDAQAELALKSEGFCEIDLQTLEIIVTRETLNTKEDVVFEAVLNWAEAECKRQGLSITPVNKRNVLGKALYLVRIPTMTLEEFANGAAQSDILTLEETRSIFLWYTAANKPQLEFPLIKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDKRIFIAGLGLYGSSCGKAEYSVKIELKRQGAVLAQNLTKFVSDGSSNTFSVWFEHPVQVEQDTFYTVSAILDGNELSYFGQEGMTEVQCGKVTFQFQCSSDSTNGTGVQGGQIPELIFYA
What is the function of this protein?
Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity).  Involved in late neuronal development and muscle formation (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing protein 6.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in punctated bodies in the cytoplasm.
Protein: EF1A_CRYPV
Sequence: MGKEKTHINLVVIGHVDSGKSTTTGHLIYKLGGIDKRTIEKFEKESSEMGKGSFKYAWVLDKLKAERERGITIDIALWQFETPKYHYTVIDAPGHRDFIKNMITGTSQADVALLVVPADRFEGAFSKEGQTREHALLAFTLGVRQMIVGINKMDTCEYKQSRFDEIFNEVDGYLKKVGYNTEKIPFVAISGFVGDNMVERSDKMPWYKGKTLVEALDTMEPPKRPTDKPLRLPLQDVYKIGGVGTVPVGRVETGIIRPGMNVTFAPAGVTTEVKSVEMHHEQMPEAVPGDNVGFNVKNVSIKDIKRGFVASDAKNDPAKGCEDFTAQVIVLNHPGEIKNGYSPVVDCHTAHISCKFQTITAKMDKRSGKVLEENPKLIKSGDAALVVMQPLKPLCVEAFTDYPPLGRFAVRDMKQTVAVGVIKSVTKKEATSKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BACC0
Sequence: MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANLSCTPEYLLIDAMKLPTPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGVLEEHRKSFAPIKDMIQK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_RICRS
Sequence: MLNVNFVNEASSTNQGLVVFIDEQLKLDSNLIGLDQQHHGLISKTIQNKLQFTGKYGQIKVIPSVIKSGEVRYLIIAGLGNEEKLTEAKIEELGGKILQHATSCKISTIGLKITNRISRFTSQTFASLVASGAFLASYRFDKYRTTLKEAEKFAVESIEIFTDNSTETAKLFEIKKLIAEAVFFTRDISNEPSNIKTPQVYAERIVDRLEPLGVDVDVIGEREMKNLGMGALLGVGQGSQNESKLVVMEYKGGSKDVPTIALVGKGVIFDTGGISLKPSSDMHLMRYDMGGSAAVVGTIIAVAGQKLPVNIVGVVGLVENMLSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAITIALGNTYAGCFSNNDELADKLIKVGEEVNEKLWRMPLHDEYDAMIHSDIADMANIANVPRAAGSCIAAHFIKRFIKDGVDWAHLDIAGVANSNKASALGPKGAVGYGVRLLEKFIKEYT
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ENTFA
Sequence: MKKYKRLLLMAGLVTLVFVLSACGTAPVSESSTGIWDRYIVYYFAQAIKFLSLGGSVGIGIILFTLVIRIILLPLMHFQTKSMRKTQELQPQLKALQQKYSSKDPETQRLFREEQQRLYAENNVNPYIGCLPLLVQLPIMMALYQAISRVPELKEGTFLWLSLDKPDPYLILPILAAVFTFASTYLSSMSQLETNASLKIMNYVMPAMIFFMGISLASSLSLYWVVSNAFQTGQTLLLNNPFKIRKEREEAARQAKARERALERAKSPKKKGKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCF24_CYAPA
Sequence: MVNTQSPKNSGLENLVNQPYKYGLPLIFEIETISKGLTEETIRLISEKKNEPQFMLEFRLQAYRKWLEMSNEPEWAHLNYPKINYQDMVYYSAPKQKKKLQSLDEVDPTLLETFEKLGIPLTEQKRLANVAVDAIFDSVSVATTFKEELAKEGVIFCPISEAVQKYPDLIKKYLGSVVSTSDNYFSCLNAAVFSDGSFCYIPKNVRCPLELSTYFRINNGESGQFERTLIVADEGSYVSYLEGCTAPQFDTNQLHAAVVELVALDNAEIKYSTVQNWYAGDENGKGGIYNFVTKRGLCAGKNSKISWTQVETGSAITWKYPSCVLLGDNSIGEFYSVALTNRYQQADTGTKMIHIGKNTRSRIISKGISAGHSQNSYRGLVKIGPKAVGARNYSQCDSLLIGDNSQANTFPHLQIKNPTAKVEHEASTSKIGEEQIFYFLQRGINAEEAISLIISGFCREVFNNLPMEFALEADKLLGLKLEGSVG
What are the official names of this protein?
UPF0051 protein ycf24.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: IF2_ACTP2
Sequence: MSDNEIKNEAPKKLSLQRRTKTTVADGKVQVEVRKSRKIDTAAVKKAQEEAALKAKQEAEAKAQAEKTAAEQAKAEAEAAKKAEGAKVEATKKSAPAVPVMPNSKPKAAAPKAEQPKQEKALDPEKEAKKKEEAELRRKQEELARQKAEMEAKRAAENARRLAEIAREEAAENGEEFEDDRFTSSYAREADRDNDRRSEANRGRGKGGVNKAKKGDREDKNERNADRRNQKDVKGKGKNAKKGSALQQAFTKPVQVNKADVVIGETITVAELANKMAVKATEIIKTMMKMGEMVTINQVIDQETAQLVAEEMGHKVILRNENELEDAVMEDRDVDAEKVTRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETEDGKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHARAAGAPIVVAVNKIDKPEANPDRVEQELLQHEVVSEKFGGDVQFVPVSAKKGLGIDDLLEAILLQSEVLELTAVKEGMASGVVIESYLDKGRGPVATILVQSGTLNKGDIVLCGFEYGRVRAMRDENGKEVDSAGPSIPVEVLGLSGVPAAGDEATVVRDEKKAREVALFRQGKFREVKLARQQKAKLENMFSNMTAGDVAELNVIVKADVQGSVEAICQSLAELSTDEVKVKVVGSGVGGITETDATLAAASNAIMVGFNVRADASARRVIEAENIDLRYYSIIYELLNEIKAAMSGMLQPEFKQEIIGLAEVRDVFRHPKFGAIAGCMVTEGVVKRNNPIRVLRDNVVIFEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVKVGDQIEVFEVVEVKRSI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P20_BYVU
Sequence: MTSSVELAQTKPLFRVLLLKGFVFYVVAFETEEESSEAELPLVYLHDFELNINKRGKIEASYVDFMSCMTRLKPSSVSYTRVSSEKSSEDFSLPGSGKTFGSKVLNRKVTFTFENGVQLVFGMYGLEQRCVSSDYLWFENVFVGAHCGTLTYCLNCELDKSGGELEILTFSKNEVLLKRW
What is the function of this protein?
Involved in systemic transport.  Necessary for long-distance transport of the virus through the phloem.
What are the official names of this protein?
20 kDa protein, p20.
What are the subcellular locations of this protein?
Virion. Note=Integral virion tail component. Presumably associates with the virion via binding to Hsp70h. Probably builts the tip segment of the virion tail.
Protein: Y3639_SHEPA
Sequence: MSRPKKCRHLSCCVPYSLFKPNGIPSTQLEKIQLEADEFEALNLGDVQKMSQLDAAALMGISRQTFGYLLASARKKVATAVTQGQALLLPQIANKD
What are the official names of this protein?
UPF0251 protein Spea_3639.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: RL11_LEPCP
Sequence: MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGIEPGLKLPVVITAYADKSFTFILKSPPASVLLKKAAKIDKGSPRPHLEKVAKLTRAQLEEIAKIKVKDLTAANMDAAVRTIAGSARSMGINVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.