PharMolix/UniProtQA huggingface dataset:
Protein: LPXK_DECAR
Sequence: MLARWLQRQWFDQRRRQPALWLLLPLAWLYAGLSALNRLLAKPKHLPVPVIVVGNIIVGGAGKTPLTLWLARQLRDRGWRPGIVSRGYGRSGDEVRTVSAQSRPEEVGDEPLLLARRSGVPVWVGRHRAVAGEALLAAHPEVNVLLCDDGLQHYALARDVELVVFDVRGAGNGWRLPVGPLREPVSRLASADAVICNGQPETLLPTATPSFEMSLKPGLFYRVDVAGQSASAESLRDRGRLYALAGIGNPERFFRTLESLGLSCETRPFPDHHRYVAADLAFAKDGILLMTEKDAVKCAGMTAGETWVLPVQAELSPALIDLIVEKLRGRQVA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: IL10_CERAT
Sequence: MHSSALLCCLVLLTGVRASPGQGTQSENSCTRFPGNLPHMLRDLRDVFSRVKTFFQMKDQLDNILLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHDPDIKEHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFSKLQEKGVYKAMSEFDIFINYIEAYMTMKIQN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NODD_RHILV
Sequence: MRFKGLDLNLLVALDALMTERKLTAAARSINLSQPAMSAAISRLRDYFRDDLFIMQRRELVPTPRAEALAPAVREALLHIQLSVIAWDPINPAESDRRFRIILSDFMALVFFDKIILRLAREAPGVSFELLPLDDDPEELLRRGDVDFLILPDLFMSGAHPKARLFEERLVCVGCPTNEQLQGQLSLEQYMSMGHVAAKFGRGLKPSVEQWLLMQHGLKRRIELVVPGFNLIPPLLSGTNRIATIPLRLVKHYERTIPLRIIEHPLPLVSFTEAVQWPALHNTDPGNIWMREIMIQEALRIGI
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PLSY_CLOD6
Sequence: MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGSTNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNWPAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIFMIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ML146_PAPSO
Sequence: MAHTHCISGLVGKLVMESEVNCNADKYYKLYKHHEDLPSVIPHIYTSVKAVEGHGTTSGCVKEWGYILEGKPLSCKEKTTYNDETRTIHHMVVAGDLMNDYKKFDATLVVNPKSNGHGCIVKWTIDYEKMNEDSPVPFGYLACYQQITEDLSSHLCASD
What is the function of this protein?
Not known; MLPs constitute up to 50% of the soluble latex protein.
What are the official names of this protein?
Major latex protein 146, MLP 146.
What is the protein family that this protein belongs to?
Belongs to the MLP family.
What are the subcellular locations of this protein?
Vacuole. Cytoplasmic vesicle. Note=Central vacuole of developing laticifers and membrane-bound vesicles of mature cells.
Protein: NDHH_AMBTC
Sequence: MTVPATRNDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNAPEELGNIQVPRRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELLYDLFETATGMRMMHNFFRIGGVAADLPHGWIDKCLDFCDYFLPEVAEYQKLITRNPIFLERVEGVGFIAEEEAINWGLSGPMLRASGIPWDLRKVDHYECYDEFDWEVQWQKEGDSLARYLVRISEMIESVKIIQQALEGIPGGPYENLEARRFDRVRNIEWNDFEYRFISKKPSPTFELSKQELYVRVEAPKGELGIFLIGDNSVFPWRWKIRPPGLINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: S1PR2_DANRE
Sequence: MTTCRLFAGFCQAVTMSKYSQYFNKTLIQVHYLTAKEMTAEELRDRIESKQSLSSLNILFVVICSIIILENLLVLIAVFRNKKFHSAMFFFIGNLAFSDLLAGSAYIANIFLSGPRTFHLTPVQWFIREGTAFIALSASVFSLLAIAIERYIAITKVKVYGSNKTCRMFLLIGACWVMSILLGGLPIIGWNCINNLDDCSAVLPLNTRYYIRFVVTIFSIILLSIVILYVRIYLIVRTSHQEATNSPAYALLKTVTIVLGVFIICWLPAFTILLLDTSCKMKQCPILNNAGIFFSFATLNSALNPLIYTLRSKDMRKEFLRVLCCWGLLNCGRPPHRCMVPLKSSSSMEHCTNKHEHQSIPIMQDCTTCV
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10910360).  S1P receptor is critical for cell migration and epithelial integrity during vertebrate embryogenesis (PubMed:10910360).  Receptor for the chemokine-like protein FAM19A5 (By similarity).  Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).
What are the official names of this protein?
Sphingosine 1-phosphate receptor 2, S1P receptor 2, S1P2, Sphingosine 1-phosphate receptor Edg-5, S1P receptor Edg-5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_ACIAC
Sequence: MKHIPRKRFGQHFLADQAIIDAIVRAIAPAPGQPMVEIGPGLAALTQPLVERLGRLTVVELDRDLAQRLRSHGQLDVIESDVLKVDFSAVAANLGAPRIRIVGNLPYNISTPILFHLLEHVGVVEDQHFMLQKEVIDRMVAQPATSDYGRLSVMLQWRYAMEDVLFVPPESFDPPPRVDSAVVRMVPHAAPAPVAPRLLEELVQVAFSQRRKLLRHTLGRWLEARQFTGTFDTQRRAEEVPVADYVALAQACA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_BACAN
Sequence: MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NDKA1_XENLA
Sequence: MAANKERTFIAIKPDGVQRGLMGDIIKRFEQKGFRLVAMKFQQASQDLLRQHYIDLKDRPFYPGLVEYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESANKEIALWFKDEELVENKSCAYEWVYEN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase A1, NDK A1, NDP kinase A1, NM23/nucleoside diphosphate kinase A1.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_EUCGG
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEVPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: APBA3_RAT
Sequence: MEFLPEPQHPPGPPTMDLEEPKGPEVPSEDHPSNTQWALGPRGPDTLSEMELDTSSVRALVQQLEALPSDLGGQFPDGAPCPLHIATGQGLATQENLDAGGLLSAEAGGDNLLGLLRCEASLPAQSVPPDPAQAAPRLLQPPEDPGGDPGWMEGTEPADNRSSSSSPELWLETAPLVTHRDPPVGTQSQETLASCPAVSEVPGPCGQEELMDGVLFGAKYLGSTQLLSERNPPPSTRMGQAQEAMDRVKAPEGETQPMTEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLAKRTTSQDRQRQLYKMLCHVFHSEDAQLIAQAIGQAFSIAYSQFLQENRIDPSQVGMQPSASASHPHNGDLDHFCNSQNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRHSSVTLSIIHCPPVTTAVIHRPHVREQLGFCVENGIICSLLRGSAAERGGVRVGHRIIEVNGQSVVAMPHARIIQLLTETREIHIKTMPAATYRLLTGQEQPVYL
What is the function of this protein?
May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.  May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN (By similarity).
What are the official names of this protein?
Amyloid-beta A4 precursor protein-binding family A member 3, Adapter protein X11gamma, Neuron-specific X11L2 protein, Neuronal Munc18-1-interacting protein 3, Mint-3.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: MURG_LACLA
Sequence: MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQGLRRSLSPQNLKTAYKFFKSVSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFTGNPRAQEVADAAAQVEKFEEPTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDIRPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIIKDEDLTGQTLVEAISNILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VSM2_TRYBB
Sequence: MPSNQEARLFLAVLVLAQVLPILVDSAAEKGFKQAFWQPLCQVSEELDDQPKGALFTLQAAASKIQKMRDAALRASIYAEINHGTNRAKAAVIVANHYAMKADSGLEALKQTLSSQEVTATATASYLKGRIDEYLNLLLQTKESGTSGCMMDTSGTNTVTKAGGTIGGVPCKLQLSPIQPKRPAATYLGKAGYVGLTRQADAANNFHDNDAECRLASGHNTNGLGKSGQLSAAVTMAAGYVTVANSQTAVTVQALDALQEASGAAHQPWIDAWKAKKALTGAETAEFRNETAGIAGKTGVTKLVEEALLKKKDSEASEIQTELKKYFSGHENEQWTAIEKLISEQPVAQNLVGDNQPTKLGELEGNAKLTTILAYYRMETAGKFEVLTQKHKPAESQQQAAETEGSCNKKDQNECKSPCKWHNDAENKKCTLDKEEAKKVADETAKDGKTGNTNTTGSSNSFVISKTPLWLAVLLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein MITAT 1.2, VSG 221.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: CYTB_RAT
Sequence: MMCGAPSATMPATTETQEIADKVKSQLEEKANQKFDVFKAISFRRQVVAGTNFFIKVDVGEEKCVHLRVFEPLPHENKPLTLSSYQTDKEKHDELTYF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-B, Cystatin-beta, Liver thiol proteinase inhibitor, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_RHOPB
Sequence: MATPANQTGRITQVIGAVVDVQFEGHLPAILNAVETKNGNNRLVLEVAQHLGESTVRTIAMDTTEGLVRGQEVTDTGNPIMVPVGVGTLGRIMNVIGEPVDEQGPVANEGLRPIHAEAPTYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESGVNKKGGGEGSKCALVYGQMNEPPGARARVALSGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTHKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLNRAISEKGIYPAVDPLDSTSRMLSPLIVGDEHYQTARMVQQVLQKYKSLQDIIAILGMDELSEEDKIAVARARKIERFLSQPFFVAEIFTGSPGKFVELADTIKGFRAICEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYS_HAES1
Sequence: MIDPTLLRNNLSEIAEKLKVRRGFILDVNKFSQLEEQRKTLQIKTETLQAERNSRSKTIGAAKARGEDISTLLAEVDHMGAELNTVKEELANVLTEIEQLALTIPNIPADEVPLGKDDSDNKEVFRWGTPKKFDFEVKDHVALGEILGGLDFAAGVKLSGARFAVIKGQIARMHRALAQFMLDLHTEQHGYTEAYVPYLVNHATLYGTGQLPKFGEELFHIKPLENEQTYALIPTAEVPVTNLVRDEIIDEADLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVEPEKSMEALEELTNQAEKVLQLLNLPYRKVLLCTGDMGFGATKTYDLEVWIPAQNTYREISSCSNMWDFQARRMQARCRAKGDKKTRLVHTLNGSGLAVGRTLVAILENYQNADGSITVPEVLRPYMNGIEIIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_HAEI8
Sequence: MAISRLLVEKFRNLTAVDLDFDPCFNFLIGNNGSGKTSLLEAIFYLGHGRSFKSAVTNRIISYDEPHFTLFGQIQESQHQWSVGLQKLRQGNTLVKINGEDGNKISDLAHLLPMQLITPEGLTLLNGGPSYRRAFLDWGLFHHQTSFYSAWSNLNRLLKQRNAALAQNQPYSAIKIWDVELAKLAHQVSQWRAEYAEALRPEIEQTCQLFLPELEINVSFHQGWEKNADYYEILQQNFERDRALNYTFSGPQKADFRFKAQGLPVEDVLSRGQLKLLMCVLRLAQGEHLMKEKQRHCIFLIDDFASELDQYKRALLAERLQQSGSQVFVTAITQRQLKEMQVENKKMFSVHNGIINALN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMYB_IPOBA
Sequence: MAPIPGVMPIGNYVSLYVMLPLGVVNADNVFPDKEKVEDELKQVKAGGCDGVMVDVWWGIIEAKGPKQYDWSAYRELFQLVKKCGLKIQAIMSFHQCGGNVGDAVFIPIPQWILQIGDKNPDIFYTNRAGNRNQEYLSLGVDNQRLFQGRTALEMYRDFMESFRDNMADFLKAGDIVDIEVGCGAAGELRYPSYPETQGWVFPGIGEFQCYDKYMVADWKEAVKQAGNADWEMPGKGAGTYNDTPDKTEFFRPNGTYKTDMGKFFLTWYSNKLIIHGDQVLEEANKVFVGLRVNIAAKVSGIHWWYNHVSHAAELTAGFYNVAGRDGYRPIARMLARHHATLNFTCLEMRDSEQPAEAKSAPQELVQQVLSSGWKEYIDVAGENALPRYDATAYNQMLLNVRPNGVNLNGPPKLKMSGLTYLRLSDDLLQTDNFELFKKFVKKMHADLDPSPNAISPAVLERSNSAITIDELMEATKGSRPFPWYDVTDMPVDGSNPFD
What are the official names of this protein?
Beta-amylase, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: GCSPA_CHLP8
Sequence: MPFIVNTDAERAEMLREIGVENFEALIADIPEEVRLKKALDLLPAMGEPEVKSLLEKMASSNAATCDHVSFLGAGAYDHFIPAAVKTIASRSEFYTAYTPYQAEVSQGTLQAIYEYQSVMCRLYGMDVANASMYDGASALAEAALIALNVTGRNGIVVAGKLHPYTSQVLETYLEAAGDRPIVQNSIEDGIGSVAALETLVSSETAAVIVQQPNFYGCLEEVEAIGEIAKKHGALFIVSADPVSLGVLEAPGNYGADIAVGEGQSVGNAQSFGGPYLGILTVKQAHVRKIPGRLVGMTKDKDGNDGFILTLQTREQHIRREKATSNICSNQALCALQAVVHLSLLGKEGIQDVANRSMQKAHYLADRITELPGFSLKFSAPFFREFVVETPVPAATIIEKMLDKKVFAGVDLSAWGEDGLLIAVTEKRTKEELDSFVSELASLG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: YIBL_ECO57
Sequence: MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKATLEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTALGREMGLQEMTGFSKTAF
What are the official names of this protein?
Uncharacterized protein YibL.
Protein: RHAT_ECOUT
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SIR3_MOUSE
Sequence: MALDPLGAVVLQSIMALSGRLALAALRLWGPGGGRRPISLCVGASGGFGGGGSSEKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR
What is the function of this protein?
NAD-dependent protein deacetylase (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655, PubMed:26620563).  Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655).  Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5PO (PubMed:16790548, PubMed:18794531, PubMed:21172655).  Contributes to the regulation of the cellular energy metabolism (PubMed:23835326).  Important for regulating tissue-specific ATP levels (PubMed:18794531, PubMed:24252090).  In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).  Acts as a regulator of ceramide metabolism by mediating deacetylation of ceramide synthases CERS1, CERS2 and CERS6, thereby increasing their activity and promoting mitochondrial ceramide accumulation (PubMed:26620563).
What are the official names of this protein?
NAD-dependent protein deacetylase sirtuin-3, Regulatory protein SIR2 homolog 3, SIR2-like protein 3, mSIR2L3.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
[Isoform L]: Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform S]: Cytoplasm.
Protein: RR3_SOYBN
Sequence: MGQKINPLGFRLGTTQSHDSIWFAQPTNYSENIQEDKKIRDCIKNYIQKNIRISSGVEGIGQIKIQKRIDLIQVIIYMGFPKLLIEGKSQKIEELQTNMQKKLNCVNRKLNIAIVKVANAYKHPNIIAEFIAGQLKNRVSFRKAMKKAIELTEQAGTKGVQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCCYTVRTIYGVLGIKVWIFSK
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL1_METM7
Sequence: MDSDKILNAVKEARTLAKPRNFTQSVDLIVNLKELDLTRPENRLKEQIVLPSGRGKDVAIAVIAKGDLAAQAEDMGLTVIRQEELEELGKNKKTAKKIANAHGFFIAQADMMPLVGKSLGPVLGPRGKMPQPVPANANLAPLVARFQKTVAINTRDKSLFQVYIGHESMSDEELAANAEAILNVVSKKYEKGLYHVKSAFTKLTMGAAAPIEK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: QUEC_COXBR
Sequence: MKKAVILISGGLDSTTCLAVAKSKGFSCYALSFDYGQKHHSELVAAEKIAAHFNVVRHEVVTLSIGKLGGSALTDNSLDVPDYGGNESIPITYVPARNTIFLSIALGWAEILDAESILIGASAIDYSGYPDCRPEYIAAFQNLANLATKRGIEGHSIKIEAPLIHLSKAETIKLGYSLGVDYSMTVSCYRANEEGLACGYCDSCELRKKGFKEAEIKDPTQYITKV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.