PharMolix/UniProtQA huggingface dataset:
Protein: GUAC_YERPA
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: PROTO_ICASP
Sequence: IVPFLGPLLGLLT
What is the function of this protein?
Mast cell degranulating peptide.  Induces the chemotaxis of neutrophils.
What are the official names of this protein?
Chemotactic peptide, I-CP.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Protonectin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMN6_GLAP5
Sequence: MSGFQFKQFFIAHDCCAMKVNTDGILLGSIADPSNARHILDLGTGTGLIAIMLAQRTASAQITALELEENAFHQAQENAQRCPWNNRIDVLQADIMTWKSTKKFDLIVSNPPYFEHSLASRNKQRDLARAVTYSHFDWLKQSQQWLTPNGRISFILPCDAGKKLLEQSHLLGLYCIEYWEICTKVGLSPKRVILTFSPQYAEMALHTLTIYDENQRYTADFTQFTEIFYLKVNSK
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAL_SALEP
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFPWIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROE_ACTPJ
Sequence: MNQYAVWGNPIAQSKSPRIHQLFGEQTGKSISYVAKLGNELNFENELMQFFAEGAKGANITAPFKERAFSLADEYSESCLLAEACNTLKRLDDGRLYADNTDGFGLCSDLERLGWLKPHQRVLILGAGGATKGVLFPLLKAKQQITIYNRTLEKAVRLAEKFAKYGKIRTASLEQIAEQQFDLIINATSLGLQGKYVPVAAHLLKSAAVYDMQYAPDMQTPFLNYARECGAVRYQDGLGMLVGQAGFAFKLWENEFPNVEKVLKQLKNEMENAK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: DDL_LACJO
Sequence: MTDKIKVGLIFGGNSSEYEVSIMSAHNIYEEIDTNKFDVYPMWITNDGYLADDADSRKVLDNPKMEVANPHKVANISNIIELKDRPEIDVFFPIVHGNLGEDGCLQGLFRVLDKPFVGDDVLAAAVTMDKEMTKILAQRAGVPVAKWIAVKRFEYNDPDNEKLDYEYVASQLGSDLFVKPSNQGSSVGVSHVTNEKEYKVALAEAFKYDDKVLVEETVHGTEVETAVLGNDKPIVAGVGQIINAKDSFYTYENKYDDDSTSTLEIPAKLPEGIVETVRKNALKVFQATECSGLARIDSMLRSEDNEVVLTEVNALPGFTNISMYPKLFEEIGIPYTDLITKLIDYAMERYDHKKTLLHKHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPE39_RAT
Sequence: MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWTGEPVGSISWSIKETAGSSGSTSEGREQMKGRNSFYTQLPKPPSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKTYSPELGRPKGEYRDYSNDWSLSDTVRRLRQGKVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHVQDQYTLLERQIIIEANDRHLESSGQTEIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPVNLKKTFKIPDRQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDVILSSSQIRWKN
What is the function of this protein?
Proposed to be involved in endosomal maturation implicating in part VPS33B.  In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity.  May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B.  May play a role in vesicular trafficking during spermatogenesis.  May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity).
What are the official names of this protein?
Spermatogenesis-defective protein 39 homolog, hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction.
What is the protein family that this protein belongs to?
Belongs to the SPE39 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Early endosome. Recycling endosome. Late endosome. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles.
Protein: GLUC_MYOSC
Sequence: LQDAEDSSRFDADDTLAGEARELSTPKXHSEGTFSNDYSKYLETRRAQDFVQWLKNSXXXXXXXXHADGTFTSDVSSYLNDQAIKDFVAKLKSGKV
What is the function of this protein?
Plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Pro-glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPS_LEGPH
Sequence: MNHKLPQHIAVVMDGNGRWAESRGLPRVEGHKAGLDSVKKIINCCLEKKISCLSLFAFSSENWSRPVTEVNFLMELFLEALRKEIDDLNQHGIRLKFTGDREPLSQILQKQMCDAEALTKNNQQLILNVVVNYGGKWDIVTAARKLIRTVLDGKLAYDEINEAVFAQFLDTNGMPEPDLFIRTSGELRISNFFLWQLAYTELYFTDVHWPDFNEHEFELALISFAKRARRFGQISQSE
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: DPH2_ASPFU
Sequence: MATEMQAAPVLSTPDSLILEATEPVARQNATRTLSDEELSITYDIERTLQEIRQARYKRIALQFPDDMLPDAPRVFQLLSRGLACRDVDKITVEKNGNGTGGVESEKLAQDVSQLSVDDKPEPEPKLYILADTSYGTCCVDEVAAEHVNADVVVHYGRSCLSPTARLPVIYVFTHKELPIEPVIQAFKATYPDQATKIILAADVTYCDHIPAVYARLMEEGYTNLYATELIHCPSSAIPNRTVPDSVRENPDTLSEWQLFHISDPPTALLLTLASRVAAIHIYPTTDAPSDNVKPLPVSTSAALGRRYAILTRLSTVPIFGILINTLSVKNYLHIVEHVKQKIADAGKKSYMFVVGKLNAAKVANFSEIGGWVVIGCWESSLVDSKDFWKPVITPFELELALKGDHERVWTGAWQSDFQSILDQPAEEAQTADHEESPNDDDDMSEPESAPPEFDLRTGRYVSHTRPMRNPAPRVSAQSDDAVSAASGPAAARALARRAKGELAMIGGTVSPGAEYLRSQRTWKGLGSDFDIQYDDEDPSDSTLVVEGRKGIARGYTVGDSIEKH
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_ALIF1
Sequence: MKPTLPNYDQSSVLIVGDVMLDRYWGGPTSRISPEAPVPVVKVEKIEERPGGAANVAMNIAALGGDAHLVGLVGEDEPAQALTTTLESLKVHCDFVALPEFPTITKLRVMSRGQQLIRLDFEDSFHDVAAEPIISRMQQALSSVKAVVLSDYAKGALEHVQLMIQEARKVNVPVFIDPKGADFERYRGATLLTPNMLEFETVVGKVKDEDDLVAKGQQIIEEFDFEALLVTRSEHGMTLLRRNMEPLHLPTQAREVFDVTGAGDTVISVLAASVSTGKPLDEACALANAAAGVVVGKLGTSTLSTIELAEAIHGSQDSGFGIIGEEQLISAVKQARARGEKVVMTNGCFDILHAGHVSYLNHAAELGDRLIVAVNTNESVQRLKGPGRPINPTDRRMAVLAGLGAVDWVVPFSEDTPQRLISQVLPSLLVKGGDYAIEDIAGGAEVIAAGGEVKVLNFEDGCSTTGIIEAIKGGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CAP9_ADE05
Sequence: MSTNSFDGSIVSSYLTTRMPPWAGVRQNVMGSSIDGRPVLPANSTTLTYETVSGTPLETAASAAASAAAATARGIVTDFAFLSPLASSAASRSSARDDKLTALLAQLDSLTRELNVVSQQLLDLRQQVSALKASSPPNAV
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: LEU1_YERPE
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PAPD7_HUMAN
Sequence: MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFASYFCLNSPALDTAAAAGAAGRGSGGLGPALPAASPPPPGPTAPAALPPALLTALGPAAEGARRLHKSPSLSSSSSSSSSNAESGTESPGCSSSSSSSASLGRPGGGRGGAFFNFADGAPSAPGTANGHPGPRGPAPAGSPSQHQFHPGRRKRENKASTYGLNYLLSGSRAAALSGGGGPGAQAPRPGTPWKSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDAESTLGRIIKVTQEVIDYRRWIKEKWGSKAHPSPGMDSRIKIKERIATCNGEQTQNREPESPYGQRLTLSLSSPQLLSSGSSASSVSSLSGSDVDSDTPPCTTPSVYQFSLQAPAPLMAGLPTALPMPSGKPQPTTSRTLIMTTNNQTRFTIPPPTLGVAPVPCRQAGVEGTASLKAVHHMSSPAIPSASPNPLSSPHLYHKQHNGMKLSMKGSHGHTQGGGYSSVGSGGVRPPVGNRGHHQYNRTGWRRKKHTHTRDSLPVSLSR
What is the function of this protein?
Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation (PubMed:23376078, PubMed:30026317).  Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism.  Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates.  Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation (PubMed:23376078).
What are the official names of this protein?
Terminal nucleotidyltransferase 4A, DNA polymerase sigma, LAK-1, Non-canonical poly(A) RNA polymerase PAPD7, PAP-associated domain-containing protein 7, TRAMP-like complex polyadenylate polymerase, Terminal guanylyltransferase, Terminal uridylyltransferase 5, TUTase 5, Topoisomerase-related function protein 4-1, TRF4-1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Excluded from nucleolus, weak staining detected in the cytoplasm.
Protein: LV861_HUMAN
Sequence: MSVPTMAWMMLLLGLLAYGSGVDSQTVVTQEPSFSVSPGGTVTLTCGLSSGSVSTSYYPSWYQQTPGQAPRTLIYSTNTRSSGVPDRFSGSILGNKAALTITGAQADDESDYYCVLYMGSGI
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 8-61.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: UGPI6_ARATH
Sequence: MTRRAEFEMGLFVILQSMFLISLCSSQKPEEFLPEISPDTSPQPFLPFIAPSPMVPYINSTMPKLSGLCSLNFSASESLIQTTSHNCWTVFAPLLANVMCCPQLDATLTIILGKASKETGLLALNRTQSKHCLSDLEQILVGKGASGQLNKICSIHSSNLTSSSCPVINVDEFESTVDTAKLLLACEKIDPVKECCEEACQNAILDAATNISLKASETLTDNSDRINDCKNVVNRWLATKLDPSRVKETLRGLANCKINRVCPLVFPHMKHIGGNCSNELSNQTGCCRAMESYVSHLQKQTLITNLQALDCATSLGTKLQKLNITKNIFSVCHISLKDFSLQVGNQESGCLLPSLPSDAIFDKDTGISFTCDLNDNIPAPWPSSSLSSASTCKKPVRIPALPAAASSQPRLHDEGVTRLVIFVLSMLLVMLLS
What are the official names of this protein?
Uncharacterized GPI-anchored protein At1g61900.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DNLJ_BURO0
Sequence: MARTQAEPPASQPDARAAWLRDQLERANHAYYVLDQPDLPDAEYDRLFRELQQLETDHPELVTPDSPTQRVGGEAAGGFTPVVHDAPMLSLNNGFADEDIVAFDKRVADALAKTTDLAGSVTDPVEYACELKFDGLAISLRYEQGVFVQAATRGDGTTGEDVTENVRTIRSIPLKLKGKHVPAVLDVRGEVLMFKRDFARLNERQRAAEQREFANPRNAAAGSLRQLDSKITAQRPLSFFAYGIGVLDGMPMPDTHSALLDWYESLGLPVNRERAVVHGAEGLLDFFRKVGEKRESLPYDIDGVVYKVNRRDEQERLGFVSRAPRFALAHKFPAQEALTKLVAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVGALLDRRPADAAEFVMPTECPVCGSKIERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVELNLVRTPADLFNLGFATLAELDRFAEKSAQNLIDSLEKAKHTTLARFIYGLGIRHVGESTAKDLAKHFGSLTPIMDASIEELLEVNDVGPIVAESLHQFFAEEHNRTVIEQLRAPGKVTWPEGPPAPKAPQGVLAGKTVVLTGTLPNLTRDAAKEMLEAAGAKVAGSVSKKTDYVVAGAEAGSKLAKAEELGIPVLDEDGLHQLLEGNTP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CH60_ALIF1
Sequence: MAAKDVKFGNDARIKMLEGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFQNMGAQMVKEVASQANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKALSVPCADTKAIAQVGTISANSDSTVGNLIAEAMDKVGRDGVITVEEGQALQDELDVVEGMQFDRGYLSPYFVNNQEAGSVDLESPFILLVDKKVSNIRELLPTLEAVAKASRPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTAGSVISEEIGLELEKVVLEDLGQAKRVTITKETTTIIDGSGEETIIQGRVSQIRQQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVEDALHATRAAVEEGVVAGGGVALIRVASKVAGLVGDNEEQNVGIRVALRAMEAPIRQITKNAGEEDSVVANNVKAGEGSYGYNAATGEYGDMIEMGILDPTKVTRSALQFAASVAGLMITTEAMVTDKPQDSGSAMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX119_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKERIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1g, Toxin-like structure LSTX-A19.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MED10_COCIM
Sequence: MAPITLSQIDEDLKDVIQTFFEIQSAVHGYLGPETQQELVKKLKSLTVSLQTLSAHAAPDPSYVQSPPSRTGLSPADPPVQSIQLPPEIIDYVDAARNPDIYTREFVELVQKSNQELKGKMEAFASFRDVLAKEMASAMPECKKEVERVVKATGGSVDGGGCG
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10, Mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3_CORK4
Sequence: MGQKIHPYGLRLGITSEWRSRWYADKQYADYLAEDIKIRDFLSKGLERAGIADVVIERTRDRVRVDIHTARPGIVIGRRGAEADRIRGKLEKLTGKQVQLNILEVKNVDASAQLVAQSIAEQLSNRVAFRRAMRKAIQGAMRQPQVKGIKVVCSGRLGGAEMGRTERYHEGRVPLHTLRAEIDYGTFEAHTTFGRIGVKVWIYKGDVVGGRRESLINARDDRGSRRGRNDRPRRGGGRRRRAAEQKQEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HT1_TRYVI
Sequence: MPEYPTEDTNASGKTSGSSPDDHTDDNAPSFFSCENLCIVQVPVSTGSLNGFSIGFVAVYMHLYEIFSGCSALESSGACSGNSKCTWIPNNSTCVWKDCNGAAGATTCKDGSGYNSLESGLFACSMIVGSMIGSIFAGKFLSKFGLKMSFIVSGVLGIVGSALIHVATRGSTLWVMCVGRFLMGLVLGLVCVASPMYVNENAHPKYRKTIGVLFQVFTTFGIMFAALLGLAIVKTPGHDKASGLLWRMQVFCSVSTALSALLLVLGLVVRKSKTSFAGGVDSAGEGVLDPNEYSVRQMLGPLAVGAVTAGTLQLTGINAVMNYAPEIMRNIGMDPMEGNSAVMSWNFVTALVAIPLVSRFTMRQLFLACSFMASCACLIMCGIPVYPGVASVDNRNIVATVGIAVFIAAFEFGVGSCFFVLAQDLFPRSFRPTGSSFVVMAQFIFNIMINLLYPITVEAISGGKGKSPEKGQSVSFIIFGIIGIICFVLQLRYLTPWEDGQGTSTSPTARCNAPTSPNNGEGEPATADMSPVEMSTPKHSGAA
What is the function of this protein?
Facilitative glucose transporter.  Binds D-fructose and cytochalasin-B, but not D-galactose.
What are the official names of this protein?
Glucose transporter HT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KAB1_OLDAF
Sequence: MAKFTVCLLLCLLLAAFVGAFGSELSDSHKTTLVNEIAEKMLQRKILDGVEATLVTDVAEKMFLRKMKAEAKTSETADQVFLKQLQLKGLPVCGETCVGGTCNTPGCTCSWPVCTRNGLPSLAA
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has antibiotic activity.  Has a diuretic effect.  Has a uterotonic effect in humans.  Active against the Gram-positive S. aureus with a minimum inhibition concentration of approximately 0. 2 microM.  Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa.  Inhibitory effect on the growth and development of larvae from H. punctigera.  The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity.  If the protein is linearized, hemolytic activity is lost.
What are the official names of this protein?
Kalata-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: GPDA_TAKRU
Sequence: MAAPKKVCIIGSGNWGSAIAKIVGANAAQNSKFDKTVKMWVFEETVNGRKLTEIINTEHENVKYLPGHKLPTNVLAVPDLVEASKDADILVFVIPHQFIGKVCDTMSGNIKKEAIGISLIKGVDEGPDGLKLISDVIQEKLGITMSVLMGANIANEVADEKFCETTIGCKNKSHGPLLKELMQTINFRVTVVEEYDVVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFARIFCTAGPVSSATFLESCGVADLITTCYGGRNRKVAKAFVKTGKSIEELEKEMLEGQKLQGPATAAEVYRILKHKNLIDKFPLFNAVYQICYQGHPVSEFISCLQNHPEHM
What is the function of this protein?
Has glycerol-3-phosphate dehydrogenase activity.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic, GPD-C, GPDH-C.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.