PharMolix/UniProtQA huggingface dataset:
Protein: ARLY_MYCA9
Sequence: MSTNEGSLWGGRFAGGPAPALAALSKSTHFDWALAPYDIQASVAHARVLRKAGLLTDEQLGALVEGLEQLGRDVASGVFVPADTDEDVHGALERGLIERVGPDIGGRLRAGRSRNDQVATLFRMWLRDAAGRISEGVLDVVQALADQAGAHPDAIMPGKTHLQAAQPVLLAHHLLAHAQPLLRDVDRLVDWDRRTAVSPYGAGALAGSSLGLDPDAIALDLGFTAAADNSIDATSSRDFAAEAGFVFAMIGIDLSRLSEDIILWGTTEFGYVTLDDSWSTGSSIMPQKKNPDIAELARGKTGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPLFDSVSQLELLLPAMAGLVATLRFHTERMAQLAPAGFTLATDLAEWMVRQGIPFRVAHEAAGEAVRVAEARGVGLEDLTDEEFAAIHPELTGDVRAVLTTAGSVASRDARGGTAPERVAEQRELVLARLNVLRGQNGRHPG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMYB_SOYBN
Sequence: MATSDSNMLLNYVPVYVMLPLGVVNVDNVFEDPDGLKEQLLQLRAAGVDGVMVDVWWGIIELKGPKQYDWRAYRSLFQLVQECGLTLQAIMSFHQCGGNVGDIVNIPIPQWVLDIGESNHDIFYTNRSGTRNKEYLTVGVDNEPIFHGRTAIEIYSDYMKSFRENMSDFLESGLIIDIEVGLGPAGELRYPSYPQSQGWEFPRIGEFQCYDKYLKADFKAAVARAGHPEWELPDDAGKYNDVPESTGFFKSNGTYVTEKGKFFLTWYSNKLLNHGDQILDEANKAFLGCKVKLAIKVSGIHWWYKVENHAAELTAGYYNLNDRDGYRPIARMLSRHHAILNFTCLEMRDSEQPSDAKSGPQELVQQVLSGGWREDIRVAGENALPRYDATAYNQIILNAKPQGVNNNGPPKLSMFGVTYLRLSDDLLQKSNFNIFKKFVLKMHADQDYCANPQKYNHAITPLKPSAPKIPIEVLLEATKPTLPFPWLPETDMKVDG
What are the official names of this protein?
Beta-amylase, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: PNCB_BUCAI
Sequence: MKRYDYPIVKTLLDTDAYKLHMQQAVFYHYKNVNVVAEFLCRGDNFLGCYANILLDQISMMRSLSLSHEEYVYMTSFPFFKKEYLHWLKKFRYNVSQVKINSYQGRLHIRISGLWKEVILWEVPILALISEVFHGNFSPEITSQSALQYLDIKLKKFFNRTKYIDLSHLKIVDFGTRRRFSYDVQYSIVKRLKESFPFLIGSSNYHIARILKIKPVGTQAHEWFQAHQQIGSNLKNSQILALQKWLYQYKNHLGIALTDSITMDAFLDDFNLHFASFYQGIRHDSGDPVKWGEKALKHYEKLGIDPCTKTLLFSDNLDFKKIISLYKKFHKKINVIFGIGTKLTCDIPYVKPLNIVIKLVECNGKPVAKISDSPGKTFCLDRIFLKNLCQVFNVSLKNR
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: IL16_SAISC
Sequence: MDYSFDTTAEDPWVRISDCIKNLFSPIMTENHSHMPLQPNVSLSEGDGTQGHPDGTPPKLETANGTPKVYRPADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRRLPDPALSVQPVPASREHPGPHTQASSIKQRISSFETFGSSQRLDKGAQRLSLQLSSGEAAKPVGKHEGGRLPGLLGRGAVPTLAPQETEQVLPSGSPAASEATDPGVSESPPPGRQPSEKTLPPSPDPLLRLLPTQTEESQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISWGQAPCIPKEGASPTSLSNEDSAANGCAETSGSDTGFSLNLSELREYTEGLTEAKEADDGDHSSPQSGQSVISLLSSEELKQLIEEVKDLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPRQAVIVTRKLTPETVPDLNSSTDSAASASAASDVSVDSTAEATVCTVTLEKMSGGLGFSLEGGKGSLQGDKPLTINRIFKGAASEQSETVQPGDEILHLAGTAMQGLTRFEAWNIIKALPDGPVTIVIKRKSMQSKGTSAAGDS
What is the function of this protein?
Pro-interleukin-16 is involved in cell cycle progression in T-cells.  Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene.  May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity).
What are the official names of this protein?
Pro-interleukin-16.
What are the subcellular locations of this protein?
[Interleukin-16]: Secreted. SUBCELLULAR LOCATION: [Pro-interleukin-16]: Cytoplasm. Nucleus.
Protein: NINE_BP933
Sequence: MRRQQRSITDIICENCKYLPTKRGIQKFSFEQNTMMSVQGGLSSLSDSQLTCIFKYCTLQRACV
What are the official names of this protein?
Protein ninE.
What is the protein family that this protein belongs to?
Belongs to the ninE family.
Protein: ACBP2_ORYSJ
Sequence: MGLQEEFEEFAEKAKTLPDTISNEDKLLLYGLYKQATVGPVTTGRPGIFNLKDRYKWDAWKAVEGKSKEEAMADYITKVKQLLEEASASTS
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with high affinity.  Can interact in vitro with linolenoyl-CoA (PubMed:21128943).  Binds palmitoyl-CoA and linoleoyl-CoA in vitro (PubMed:28471368).  Binds phosphatidic acid (PA) and phosphatidylcholine (PC) in vitro.  May play a role in the biosynthesis of phospholipids (PubMed:24738983).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 2, Acyl-CoA binding protein 2, OsACBP2.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSBF_MARPO
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGAISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: B561G_ARATH
Sequence: MATLILSFLLLLLATKLPESLAGHCTTTTATKSFEKCISLPTQQASIAWTYHPHNATLDLCFFGTFISPSGWVGWGINPDSPAQMTGSRVLIAFPDPNSGQLILLPYVLDSSVKLQKGPLLSRPLDLVRLSSSSASLYGGKMATIRNGASVQIYASVKLSSNNTKIHHVWNRGLYVQGYSPTIHPTTSTDLSSFSTFDVTSGFATVNQNSGSRALKVTHGVVNAISWGFLLPAGAVTARYLRQMQSIGPTWFYIHAAIQLTGFLLGTIGFSIGIVLGHNSPGVTYGLHRSLGIATFTAAALQTLALLFRPKTTNKFRRYWKSYHHFVGYACVVMGVVNVFQGFEVLREGRSYAKLGYCLCLSTLVGVCVAMEVNSWVVFCRKAKEEKMKRDGLTGVDRCSGSHS
What is the function of this protein?
May act as a catecholamine-responsive trans-membrane electron transporter.
What are the official names of this protein?
Cytochrome b561 and DOMON domain-containing protein At2g04850, Protein b561A.tha7.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RGXT2_ARATH
Sequence: MAQKQQTLHQQRPFSSSPRSYSSISNRPIFLLSRNGLLLVLLALFLLLGVFLPWPGSPLLLFPNKVSSPSYASSLSPHAKSEWRNYTLAQAAKFVATNGTVIVCAVSSPFLPFLNNWLISVSRQKHQEKVLVIAEDYITLYKVNEKWPGHAVLIPPALDSKTAYSFGSQGFFNFTARRPQHLLQILELGYNVMYNDVDMVWLQDPFQYLEGSHDAYFTDDMPQIKPLNHSHDLPAPDQNGETYICSCMIYLRPTNGAKLLMKKWSEELQSQAWSESIRFKANDQPAFNLALNKTAHQVDLYLLSQVAFPTGGLYFNDAAWVKETKGKHVIVHNNYIIGYDRKMRRFQDYGLWLVDDHALESPLGKLQ
What is the function of this protein?
Catalyzes the transfer of D-xylose from UDP-alpha-D-xylose onto L-fucose.  Probably involved in the biosynthesis of rhamnogalacturonan II (RG-II) through xylosylation of the internal fucose moiety of the A-chain of RG-II, a structurally complex pectic polysaccharide of the primary cell wall.  RG-II is essential for the cell wall integrity of rapidly growing tissues such as roots and pollen tube growth and elongation.
What are the official names of this protein?
UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase, Rhamnogalacturonan xylosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: PPNP_SALTY
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPASYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: CLPP_GEOSM
Sequence: MLVPIVVEQTGRGERSYDIYSRLLKDRIIFLGGGIDDNVANLVIAQLLFLEAEDPDKDIHLYINSPGGVVTAGMAIYDTMRYIKAPVSTICVGQAASMGAFLLSGGEKGKRYSLVNSRIMIHQPLGGFQGQATDIHIHAKEILRMKDELNALLAEHTGQSVEKVAADTERDYFMSGEEAKNYGIIDAIVTRNVVPGGAN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_STRZT
Sequence: MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLESKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PTFB2_SHIFL
Sequence: MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHLAQTA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FrwABC PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-like EIIB component 2, Fructose-like phosphotransferase enzyme IIB component 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_KLEP3
Sequence: MTRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKQRIHLYDHHVGLVVEQLRCITEGKSTDVDFLLRVKQQYTQLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERPFRTLPRPLAKDFFPERGWSHLLGKVLSDLPLRLAWQNKARDIGYIIASLQEALGEELLATCHLQVANELFYRNKAAWLVGKLVMPMATLPFLLPIHRSDEGELFVDTCLTTHAEASIVFGFARSYFMVYAPLPGALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLHYITRCDEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEVTAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIAPGLLALLQAEAGNKLTDLGDRIVISHLYIERRMVPLNLWLEQVNGQALRDAVEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRQIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLLRADYWRELQTRIKNGHVEDVYAYRRKQRFSVRYGADSRPDKVFTPPSGRVRRSA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEY_ARATH
Sequence: MSDETTSSPSPAPAKKKQNLGWMEWMRGWSSVFGEILFQRITASHLENPLPLPSVNDLTCVVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELILQWQNEWSGKGLPLNIEAMEIDLLSLDSVARFAEAFNARLGPLHVLINNAGMFAMGEAQKFSEEGYEQHMQVNHLAPALLSVLLLPSLIRGSPSRIINVNSVMHSVGFVDPDDMNVVSGRRKYSSLIGYSSSKLAQIMFSSILFKKLPLETGVSVVCLSPGVVLTNVARDLSRILQALYAVIPYFIFSPQEGCRSSLFSATDPQIPEYWETLKNDDWPVCPFISQDCRPANPSEEAHNTETAQRVWKKTLELVGLPLDAVEKLIEGENIQCRYGAQHE
What is the function of this protein?
Putative oxidoreductase (By similarity).  Required for vegetative shoot apex development, especially during leaf positioning and for shoot apical meristem (SAM) maintenance (PubMed:7849756).
What are the official names of this protein?
Dehydrogenase/reductase SDR family member FEY, Protein FOREVER YOUNG.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: K_BPPHS
Sequence: MSRKIILIKQELLLLVYELNRSGLLAENEKIRPILAQLEKLLLCDLSPSTNDSVKN
What is the function of this protein?
Somehow affects phage production, although the protein does not seem to be essential.
What are the official names of this protein?
Protein K.
What is the protein family that this protein belongs to?
Belongs to the microvirus K protein family.
Protein: LIPB_LEGPA
Sequence: MIIHNLGIKDYTEIWEQMKEFTATRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIKIVQSDRGGQVTYHGPGQLVAYVLMDIRRRNLGIRTLVVKLEEILISVLEHYRIPANIRSGAPGVYVGEKKVASIGLRVKNGCTYHGIALNVNMDLSPFLGINPCGFAKMEMTQMSHFHPNIQLEDVSQHFVQYFLTQFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_DELAS
Sequence: MKIHEYQGKDILRQFGVPVPRGIPAFTVQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKVAKSIDDVKALAGQILGMQLVTHQTGPEGQKVRRLYIEDGADIQKEYYLSCVTDRGTQKVAFIASSEGGMDIEEVAHSTPEKIITIFVDPLVGLTQAQGEELAKGIGMPADSTAQFIDICQKLYKCYMDTDASLVEINPLNRDSKGNVVALDAKFNFDANALFRLPEIVALRDLDEEDPAEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATPEKVTEAFKIMLKNPKVEGILVNIFGGIMKCDTIATGVITACKAVNLQVPLVVRMKGTNEELGKKMLAESGLPIISADTMAEAATKIVEAVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RECA_RUMA7
Sequence: MAIDKKKKEKDVKVHNITDAEEKKKALETAIAFIEKQFGKGAIMKLGDARAMDVEAIPTGSMMLDMALGIGGVPRGRIIEIYGPESSGKTTVALHIIAETQKMGGEVAFIDVEHALDPVYAKNLGVDIDSMLVSQPDSGEQALEIAEALARSGAIDCIVIDSVAAMVTKAEIDGEMGDTHVGQLARLMSQAMRKLTGVVSKSNTTCVFINQVREKIGVMYGNPETTPGGRALKFYASVRIEVRRGEQIKDGGEVLGNRTKCKVVKNKVAPPFKECEFDIMYGKGISRVGEVLDTAVDLGIVKKGGAWFSYEDYKLGQGRDNSKQFLLDHPDIMAEIENKIKASSAEMIAAAGQKNDKKSKLEEKANAGAGISEASEPDSSAEEDFEEFAPIDIGSLGE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_COXBR
Sequence: MKQFRGTTILSVRRNGKVVIGGDGQVSMGSTIMKANARKVRRLYNGKVIAGFAGGTADAFTLFERFESKLEKHSGNLTRAAVELAKDWRTDRILRRLEALLTVADSKASLIITGLGDVIEPEQSLMAIGSGGSFAQAAAKALLENTKLSARKIVEKALTIAADICIYTNLNFTIEELDSES
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2B3_RAT
Sequence: MDTSVLLLLAVLLSFLLFLVRGHAKVHGHLPPGPRPLPLLGNLLQMDRGGFRKSFIQLQEKHGDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIMQEYGVSFVNEERWKILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKNHQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLKYFPGVHREIYKNLKEVLDYIDHSVENHRATLDPNAPRDFIDTFLLHMEKEKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVIGSQRVPTLDDRSKMPYTEAVIHEIQRFSDVSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAFMPFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNTIDMTPKESGLAKVAPVYKICFVAR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2B3, CYPIIB3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PEPQ_PSEHA
Sequence: MEKLAVLYAEHIATLQQRTRTICEQEGLEGLVIHSGQAKRQFLDDMYYPFKVNPHFKAWLPVIDNPHCWIVVNGSDKPKLIFYRPIDFWHKVPDEPRDFWAEYFDIELLLQPDQVEKLLPYDKAKFAYIGEYLEVAQALGFSIMNPEPVLNYIHYHRAYKTQYELECLRNANRIAVDGHKAARDAFFNGGSEFDIQQAYLMATRQSENEMPYGNIVALNENCAILHYTHFEPKAPQTHNSFLIDAGANFNGYAADITRTYDFKKQGEFADLVNAMTAHQIELGKSLKPGLLYGDLHIDCHNRIAQLLSDFDIVKLPAAEIVERQITSTFFPHGLGHHLGAQVHDVGGFMRDETGAHQAPPEGHPFLRCTRLIEKNQVFTIEPGLYFIDSLLGDLAQTDNKQFINWEKVEAFKPFGGIRIEDNIIVHEDSLENMTRNLLLD
What is the function of this protein?
Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position and a nonpolar amino acid at the N-terminal position.  Also catalyzes the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds including nerve gases such as diisopropylfluorophosphate (DFP), O-isopropyl methylphosphonofluoridate (sarin), O-pinacolyl methylphosphonofluoridate (soman), and O-cyclohexyl methylphosphonofluoridate.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, DFPase, Imidodipeptidase, Organophosphorus acid anhydrolase, OPAA, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: AMPB_MOUSE
Sequence: MESGGPGNYSAAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLSGTATLELRCLLPEGASELRLDSHSCLEVTAATLRRGQPGDQQAPAEPVPFHTQPFSHYGQALCVAFRQPCGAADRFELELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKFFFQMSHPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMNVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWVTSEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKDTFAATASQLHSNVVNYVQQILAPKDS
What is the function of this protein?
Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14.  Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity).
What are the official names of this protein?
Aminopeptidase B, AP-B, Arginine aminopeptidase, Arginyl aminopeptidase, Cytosol aminopeptidase IV.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_SHEDO
Sequence: MTGPDTHAVKQFLLALQTNICAELEQLDGEASFKAESWQRAEGGGGTSRVLTQGKLFEQAGVNFSHVKGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIASKEGADPVWWFGGGFDLTPYYPFKEDVLSWHQTAADLCAPFGEEVYPKYKKWCDDYFFLPHRNETRGVGGLFFDDLNQAGFEQSFAFMRAVGEGFIQAYAPIVERRKALSFGEHERQFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWEYGFTPAAGSVEAELYEVYLKPQDWLQQA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSAD2_PIG
Sequence: MWTLVPVTFALRLLSTFVQPLGSLGSSLGPLFLWLWAAFWRAGGDRSRQQLQGKTEAGEPPRAQEDSHLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLWLLKEAGMEKINFSGGEPFIHDRGEYLGKLVRFCKEELQLPSVSIVSNGSLIWERWFKSYGEYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRTWCRDYKVAFKINSVINRFNVEEDMTEHIKALNPVRWKVFQCLLIEGENVGEDALREAEQFVISDEEFEEFLDRHKDVSCLVPESNRQMRDSYLILDEYMRFLNCRNGRKDPSKSILDVGVEKAIKFSGFDEKMFLKRGGKYVWSKADLKLDW
What is the function of this protein?
Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon.  Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism.  In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication.  Therefore, inhibits a wide range of DNA and RNA viruses (PubMed:32719955, PubMed:31517388).  Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6.  Plays a role in CD4+ T-cells activation and differentiation.  Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities.  Can inhibit secretion of soluble proteins (By similarity).
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2, SAND, Inflammatory response gene 6 protein, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible, Viperin.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RSAD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane.
Protein: MAG1_SCHPO
Sequence: MTLDIEEKEEIVTSLTKAEIHLSGLDENWKRLVKLVGNYRPNRSMEKKEPYEELIRAVASQQLHSKAANAIFNRFKSISNNGQFPTPEEIRDMDFEIMRACGFSARKIDSLKSIAEATISGLIPTKEEAERLSNEELIERLTQIKGIGRWTVEMLLIFSLNRDDVMPADDLSIRNGYRYLHRLPKIPTKMYVLKHSEICAPFRTAAAWYLWKTSKLADYTKPVRPKKH
What is the function of this protein?
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.  Can release ethylated and propylated bases from DNA in addition to 3-methyladenine.
What are the official names of this protein?
DNA-3-methyladenine glycosylase 1, 3-methyladenine DNA glycosidase 1, 3MEA DNA glycosylase 1.
What is the protein family that this protein belongs to?
Belongs to the alkylbase DNA glycosidase AlkA family.