PharMolix/UniProtQA huggingface dataset:
Protein: CDS1_MYCTA
Sequence: MSGGACIAVRSLSRSWTDNAIRLIEADARRSADTHLLRYPLPAAWCTDVDVELYLKDETTHITGSLKHRLARSLFLYALCNGWINENTTVVEASSGSTAVSEAYFAALLGLPFIAVMPAATSASKIALIESQGGRCHFVQNSSQVYAEAERVAKETGGHYLDQFTNAERATDWRGNNNIAESIYVQMREEKHPTPEWIVVGAGTGGTSATIGRYIRYRRHATRLCVVDPENSAFFPAYSEGRYDIVMPTSSRIEGIGRPRVEPSFLPGVVDRMVAVPDAASIAAARHVSAVLGRRVGPSTGTNLWGAFGLLAEMVKQGRSGSVVTLLADSGDRYADTYFSDEWVSAQGLDPAGPAAALVEFERSCRWT
What is the function of this protein?
A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S.  The H(2)S produced by this enzyme stimulates respiration in M. tuberculosis, mediated primarily via cytochrome bd with a lesser contribution from cytochrome bc1/aa3.  H(2)S modulates the balance between respiration and glycolysis, and also contributes to redox homeostasis.  Probably eliminates toxic levels of Cys (which can induce oxidative stress).
What are the official names of this protein?
L-cysteine desulfhydrase Cds1.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.
Protein: GI_EHV1B
Sequence: MAKLTGMFSAAILLSMAICSTAIIYRGEHMSMYLNASSEFAVYPTDQSLVLVGHLLFLDGQRLPTTNYSGLIELIHYNYSSVCYTVIQTISYESCPRVANNAFRSCLHKTSKHYHDYFRVNASVETNVLLNITKPQPTDSGAYILRVKLDHAPTADVFGVSAFVYDLKSKTVPDPMPTTQTVEPTTSYVSTPTYDYTDDVTTETESTSTSTQQAMTSTQTPSATWGTQLTTELPTNETVVIGQEALLCHWFQPSTRVPTLYLHLLGRTGNLPEDVLLVEDSEFLRTTSPAHRPSASPADGDDFKQTNSTSLKARNKIVAMVVIPTACVLMLLLVVVGAIINGAVRKHLLSCASRRIYRSGQGGASAAERRRLTCGPTLAASSESLADDTTSSPPTPKPSKKTKLETDPLMEQLNRKLEAIKEES
What is the function of this protein?
In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions.  Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions.  Implicated in basolateral spread in polarized cells.  In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.  Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.
What are the official names of this protein?
Envelope glycoprotein I.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein I family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN). The heterodimer gE/gI then redistribute to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: NEP_I54A2
Sequence: MDPNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHKLKITENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ACPS_STRT1
Sequence: MIFGHGIDLQEISAVKKAYDRNPRFAKKVLTPKEWERFESLSGERQMSFLAGRWAGKEAFSKAWGTGIGAVGFKDIEILNNDKGAPVVTQSPFEGNVFISISHSGDFVQASVILEKTKR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_ESCF3
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETDVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GATA_FRATF
Sequence: MSYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISAGKQGLLTGIPILHKDLFCTKGIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMDEFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAGFAPISTGSDTGGSVRQPASFCGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQNHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEALSTYYIITPAEAAANLARYDGIRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVLASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPSEAFKKGDKLDPVSAYLSDIYTIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQARI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ORN_CORGL
Sequence: MSESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVHATEEELAQMDDFVTNMHESSGLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNSIATDRAFIREHMPRLDEALHYRMVDVSSVKELARRWYPRVYYKQPEKGLAHRALADIVESIRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_AQUAE
Sequence: MRAVILAAGLGTRFKSEKPKVLHEILGKPMLWYVITNVRNGRIDDIAVVVGHKAQEVMEAFKNENLKFFIQENPKGGTADAVLAAKDFFSSYEGYVLIINGDSPLVSGETIRNMQQFIHMVRTYEGIKLGGVVLTTHLPDPTGYGRIIKEEGTDRIIRIVEEKDATPEEKAITEINAGTYIFYAPYLLEALYRIKPSPVTGELYLTDVIEYMVNKGYEVRSFMAKEPTEALGVNTRWDLALVENVIKLKIARYWAERGVTVHYPETVWIEPDVSIEPDVEIFPDVMLKGKTKIKKGSVIGKGSVIKDSLVEENVIVREYSVIENSEIKKRAVVGPFARIRNESVIGEEAEIGNFVEVKKSSIGKGVKAKHLAYIGDATVGENTNIGAGTVFANYDGKRKYESYVGKSAFIGSNSLLIAPIRVGDWAYIAGGSVVNKDIPEGALAVSRPELKIFEGRGKKKLQKD
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_PSEFS
Sequence: MKQFIDFIPLLLFFIVYKLDPRVIDLAGHELTFGGIYSATAVLIISSVVVYGAIFISQRKLEKSQWLTLVACLVFGSLTLAFHSETFLKWKAPVVNWLFALAFIGSHFIGDRLLIKRIMGHALTLPEPVWTRLNVAWIVFFLFCGAANLFVAFTFQDYWVDFKVFGSLGMTVLFLVAQGIYLSRHLHDADPTTPKTED
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS2_HISS2
Sequence: MAQVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGPRNGVHIINLEKTVPMFNEALVELTRIASNNGRILFVGTKRAASEVVKAAALDCQQYYVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALVRTREMEKLELSLGGIKDMGGLPDAIFVIGADHEHIAIKEANNLGIPVFAIVDTNSSPDGVDFVIPGNDDASRAIQLYLSAATTAVKEGRNQETVTEEVFAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CAPSD_BPFD
Sequence: MKKSLVLKASVAVATLVPMLSFAAEGDDPAKAAFDSLQASATEYIGYAWAMVVVIVGATIGIKLFKKFTSKAS
What is the function of this protein?
Self assembles to form a helical capsid wrapping up the viral genomic DNA.  The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm.  The virion assembly and budding take place at the host inner membrane (By similarity).
What are the official names of this protein?
Capsid protein G8P, Coat protein B, Gene 8 protein, G8P, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass type I membrane protein. Note=prior to assembly, the major capsid protein is found associated with the bacterial host inner membrane.
Protein: ZIPA_SHEDO
Sequence: MEDLQLVLFVLGAIAIIAVLVHGFWSIRKQQPKPIKERTRAQNISEAQRRDSQGFDADGIGAVRVRKPGTEDLPSSRNHTSVPVMTLQKASATDAGVASSHGYSPERTTAERAEPVRAERAATNATVAGSMNTQPVTPQPASYGVQGVTAEVKQSVEPQTITPSQHVHIESPKYGATTQASPQPASPVQSQAPREPEPLGEPQDVLVLHVVAHEGQEIQGAELLPCLLSLNFKFGDMNIFHRHSDNAGNGKVLFSLANMMKPGVFDPDNMEQFCTQGIVMFMTLPCHGEAQHNFSIMLNSAEQLADDLGAIVLDEQRKVWTEHNKQDYLRRIKAIV
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: FUB3_GIBF5
Sequence: MRSRRDNSWVAQKFGGTSIGKFPDKVAEIVKSARLGGDRPAVICSARSSGKKVFGTTSRLLQVYRTLRGIVAITQDPDMQELLFDRLRSIIRDIRDDQVATVQMYILRQDIRDDTIRQITADCQELLDYTSAAKRFNLDINGKAKDKMVSFGEKLSCRLMVAMLRDRDIPAEYVDLSDIVPSNNLDQLRPDFFHEAAAVFGKRVEACNGRVPVITGFFGAVPGSLIDSGIGRGYSDLCAVLVAIGLHAERVQIWKEVDGIFTADPREVPDARCLPSITPSEAAELTFYGSEVIHHLALSLAIQAKPPVSIFVKNVQKPWGQGTVVVPTDGDDTSSWPIDYLDPSDSDSTSSTALPKMPTAVTIKRDITIFNILSNKQSMSHGFFVKVFTILAEHDISVDLISTSEVHVSMAINSSNMDPSQIKNVQCRLAEEGEVNVLPDMAILSLVGAELKNMTGIAGKMFAILGEQDVNIEMISQGASEINISCVIPDKDATRALNMLHDELFTKNAI
What is the function of this protein?
Aspartate kinase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:24389666, PubMed:26662839).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (PubMed:26662839).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (PubMed:26662839).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (PubMed:26662839).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the sulfhydrylase FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (PubMed:26662839).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (PubMed:26662839).
What are the official names of this protein?
Aspartate kinase FUB3, Fusaric acid biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: SECB_BRUA1
Sequence: MSDKAAGETKNGNGATTEPSLNILAQYVKDLSFESPGAPLSLRPREKAPSININVNVNANPLSETDFDVVLTLEAKAVDGKDILFNTELVYGGVFRIQGIPQEHMLPLLFIECPRLLFPFARQIIADATRNGGYPPLMIDPIDFAQMFQQRMAEEQAKSAVKS
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS12_PENRW
Sequence: MPSSLTPQQAAELNKSIIAYLSAHGLAETLAAFRKESDFPDNMFDATAAKQYENLLERKWTSNSTLMKKLLALESHNKALRNELNSTRPSFLNRNADVNDWLPQHPIRSLESHRDSINCIAFHPKYSLIASGSGDLTIRIWDWEDSTLERTLKGHTMAVCDVDYGDTSSGILLASCSSDFTIKLWDTTDDYKNVKTLRGHDHIVSAVRFIPSGNLLASASRDMKVILWNVINGYRVKTIEDHTGWVRDISPSFDGQFLLSTGDDMTVRLWEISASQPICKFTATGHENRILCCAVAPATSFRYLASFLESRGSTIAAEITATGSRDKSIKLWDSHGRCIMTLTGHASWVRAIAFHPGGKYLLSVSDDKTMRCWDLSQQGRCVKSISNAHDGFITCLKWVPGIAKDTRNGTMTISYQRKGSAELPRSKLDEVGQPGVQIRCVLATGGEDQKIRVFALQANDRSHK
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein nudF 2, Lissencephaly-1 homolog 2, LIS-1 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: DXR_THEP1
Sequence: MEERTLVILGATGSIGTQTLDVLKKVKGIRLIGISFHSNLELAFKIVKEFNVKNVAVTGDVEFEDSSINVWKGPHSIEEMLEALKPDITMVAVSGFSGLRAVLSSLEHSKRVCLANKESLVCGGFLVKKKLKEKRTELIPVDSEHSAIFQVIEPEVEKVVLTASGGALRDWEISKIDRARPEDVLRHPVWNMGARITVDSATMVNKAFEVLEAMELFELPFEKIEVKIHREGLVHGAVVLPDGNVKMVVSPPDMRIPISYALFYPRRVALEPFFLRTISLSFEDPDPEKYPAFFLLKEIKDSYALRTAFNAADEVAVEAFLKGRIRFGGIHRVIEKTLEEFQGYPQPRTLDDVERIHFEAIKKAERVTEWLSSTSY
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TRUA_LAWIP
Sequence: MPRLKFTLAYVGTAYHGWQTQRRKSLPELPTIQSTLEKVIASIIGKPVRVCGAGRTDAGVHAEGQVAHVDIPESKLKLDWQLVLNASLPKNIRVVHSLYVEDTFHAQHDAVQKLYAYRLWLNHRYTPPVLYPFVWSCGRLDLEAMDKASTFLLGTHNFVSLQNRGTKLLSTVRTISALYREPSQFFSLNESHEVTWFFKADGFLKQMVRNIMGLLVLVGRRKIQPEKIPYILEAKDRRHSAPTAPAHGLTLKKVFYS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YLXY_BACSU
Sequence: MYKKFVPFAVFLFLFFVSFEMMENPHALDYIGAMKKDTVTVTASKDPLYEELLQKAPEYEVKPQNARIDKVWKSIPGYNGLKVNIEQSYKKMKQHGKFREKDLVYSQVKPSVHLESLQPEPIYKGNPDKPMVAFLINVAWGNEYLEKMLPILQKHQVKATFFLEGNWVRNNVQLAKKIAKDGHEIGNHSYNHPDMSKLTTGRISEQLDKTNEQIEQTIGVKPKWFAPPSGSFRKAVIDIAAEKQMGTVMWTVDTIDWQKPAPSVLQTRVLSKIHNGAMILMHPTDPTAESLEALITQIKDKGYALGTVTELMDETRLLK
What are the official names of this protein?
Uncharacterized protein YlxY.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
Protein: PDXS_BACC2
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPERFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: IFRD2_HUMAN
Sequence: MAWNSPSRRPVWQGGAPREDGGARGVWLPSSGQVSAQRTGRRLVGLEPTPTGSLTPRPPRPVPGMPRARKGNTLRKGGQRRGGGARSSAQADSGSSDDEAASEARSTASECPSLLSTTAEDSLGGDVVDEQGQQEDLEEKLKEYVDCLTDKSAKTRQGALESLRLALASRLLPDFLLERRLTLADALEKCLKKGKGEEQALAAAVLGLLCVQLGPGPKGEELFHSLQPLLVSVLSDSTASPAARLHCASALGLGCYVAAADIQDLVSCLACLESVFSRFYGLGGSSTSPVVPASLHGLLSAALQAWALLLTICPSTQISHILDRQLPRLPQLLSSESVNLRIAAGETIALLFELARDLEEEFVYEDMEALCSVLRTLATDSNKYRAKADRRRQRSTFRAVLHSVEGGECEEEIVRFGFEVLYMDSWARHRIYAAFKEVLGSGMHHHLQNNELLRDIFGLGPVLLLDATALKACKVPRFEKHLYNAAAFKARTKARSRVRDKRADIL
What are the official names of this protein?
Interferon-related developmental regulator 2, Protein SKMC15.
What is the protein family that this protein belongs to?
Belongs to the IFRD family.
Protein: KIF25_HUMAN
Sequence: MTWTSGQLQREKQARPGSGAVLAFPDDKDLRVYGPAESQSAVFGDVCPLLTSLLDGYNVCVMAYGQTGSGKSYTMLGRHSDDGPVLPLDPQSDLGIIPRVAEELFRLILENTSRSPKVEVSIVEVYNNDIFDLLAKDSIAAVSGVKREVVTAKDGRTEVALLASEAVGSASKLMELVHGGLQLRAKHPTLVHADSSRSHLIITVTLTTASCSDSTADQACSATLPREQTEAGRAGRSRRASQGALAPQLVPGNPAGHAEQVQARLQLVDSAGSECVGVSGVTGLALREMACISRSLAALAGVLGALLEHRGHAPYRNSRLTHLLQDCLGGDAKLLVILCISPSQRHLAQTLQGLGFGIRARQVQRGPARKKPPSSQTEGKRRPD
What is the function of this protein?
Minus-end microtubule-dependent motor protein (By similarity).  Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase (PubMed:28263957).  Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis (PubMed:28263957).  May also act as a negative regulator of amino acid starvation-induced autophagy (PubMed:22354037).
What are the official names of this protein?
Kinesin-like protein KIF25, Kinesin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: FB166_ARATH
Sequence: MTMISDLSKDLVEEILSKAPITSLGAVRSTHKQWNALSKGRLLYKAEAKDQFLGFMVMDHRFLSMIFHLNGILKGDGEGFDRPSIREVGDIVNQIDISKVFQCDGLVLCVPSDNSSVVVWNPYLGQTKWIEAREPHDESDMFALGYDKDKNHKILRLYDECYYYYEVYNFKTESWGEEDHLPGWDIDSYNRGVSLNGNTYFLTQEQRAKDKYRVFLLCFNFTTEKFENFIAMPFKYHRKYVGTLSCVGNEKLAALYQRWDTGEMAIWVTTKIESNEVLWSNLFKVDMKPLVRFGFQQCKDEAGSFFIDEEKKLAVVFNLDKKRGKRNNKTRCYHTAYIIGEKGYLKKEVLGEAVEVRKDVYRSALVCSSSYVPSLEKINQIEEEEEDKCKSIKMVDTKRQRKKRKRKSKR
What are the official names of this protein?
F-box protein At3g19890.
Protein: RL21_PORGI
Sequence: MYVIVDIQGQQMKVEQGRRLFVHHIKDVESGASVEFDKVLLVDNNGAITVGSPLVEGAKVVCEVLTPLVKGDKVLIFHKKRRKGYRKLNGHRQQFTEILVKEVVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RS2_BACC2
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAYRTMRDIAAEGGDILFVGTKKQAQEAIKEEATRAGMYFVNQRWLGGTLTNFQTIQKRIKRLKDIERMQEDGTFEVLPKKEVVQLKKELERLEKFLGGIKDMKGLPSALFVVDPRKERIAVAEARKLHIPIIGIVDTNCDPDEIDHVIPANDDAIRAVKLLTSKMADAILEAKQGEETVTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: KGUA_BORPE
Sequence: MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPSLVLSISCTTRAPRPGEQDGREYRFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQRYPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEIAHAPECEYVIINQEFSVALTELVQIISAARLRFSSQAVRNAQLFSQLGIPAAH
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MES12_ARATH
Sequence: MGNRVICMKKKDVVIRSGGDGSRSKRVNRSQRKLLADEENLHRRALSMAIHQAQVSQRFDGSMSRRIGSTSSRRGTLSDSFSNNKQVPEFLESLKVKKFVLVHGEGFGAWCWYKTIASLEESGLSPVTVDLAGSGFNMTDANSVSTLEEYSKPLIELIQNLPAEEKVILVGHSTGGACVSYALERFPEKISKAIFICATMVTDGQRPFDVFADELGSAERFMKESQFLIYGNGKDNPATGFMFEKQHMKGLYFNQSPNKDIALSMISMRPVPLGPMMEKLSLSAERYGKGRRFYVQTLDDLALSPDVQEKLVRENSPEAVFKIKGSDHCPFFSKPQSLHKILLEIAQIP
What is the function of this protein?
Putative methylesterase.
What are the official names of this protein?
Putative methylesterase 12, chloroplastic, AtMES12.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASBF_BACAN
Sequence: MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDKTLEITMISDYLDISLSADFEKTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQEYVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLGEVDHPNLKINLDFLHIWESGADPVDSFQQLRPWIQHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEIIQEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRNLEVVTS
What is the function of this protein?
Involved in the biosynthesis of petrobactin, a catecholate siderophore that functions in both iron acquisition and virulence (PubMed:17189355, PubMed:18955706).  Catalyzes the conversion of 3-dehydroshikimate to 3,4-dihydroxybenzoate (3,4-DHBA) (PubMed:18955706).
What are the official names of this protein?
3-dehydroshikimate dehydratase, 3-DHS dehydratase, DHSase, Petrobactin biosynthesis protein AsbF.