PharMolix/UniProtQA huggingface dataset:
Protein: AP5M_ARATH
Sequence: MPSGCSIRALWIINNQDTVVFSRRFPVVEKQWCSAYKTENENTGLDLPRLPTDQQISDSFTRRKRREGSTRGYGIRVAQSTKGSDSWVDDPITRHIISLCLTEEDDDDDDERNILWPIALHTKALYSILVLPLVEPKEMKDYVKLCRRSDCGPAVGEDLSLSSLLLNISSITGAFMVAHAFGDIISGDTVEPEVVVSVSPSVGGLFDSLTGSIGISSRAKPVAAPVASSNPSGAAITGATASDAPKAGSRLLDRDLLRNFIATAMPFGTPLDLSLSNISAMKANGFSSADPPPQELKQPAWKPYLYKGKQRLLFTIHETVSAAMYDRDEIPDNVSVAGQINCRAELEGLPDVSFPLAGLSTAHIEAISFHPCAQVPAHGIDKQNIVFQPPLGNFVLMRYQAGCGLGPPVKGFYQLSMVSEDEGAFLFKVHLMEGYKAPLSMEFCTITMPFPRRRIVAFDGTPSAGTVLTTEHSVEWRILGSGRSLSGKSLEATFPGTIKFSPLQSRRKGDGDDEESEDESAENVVNVEDFLVQKMNKDLPAAELEEPFCWQAYDYAKVSFKIVGASVSRMSIDTKSVNIYPTTKSPVEFSAQVTSGDYILWNTLGKAPSAAVV
What are the official names of this protein?
AP-5 complex subunit mu, Adaptor protein complex AP-5 subunit mu, Adaptor protein-5 mu-adaptin, Adaptor-related protein complex 5 subunit mu, Mu5-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSRP_PORGI
Sequence: MKEKIQKNILIKNKRATFDYEILDVYTAGIVLVGTEIKSLRLGKGGLVDTYCYFHRGELWVKNMYIAEYFYGTYNNHVARRDRKLLLNRKELRKLEEASKSMGTTIVPLKLFINERGLAKLQIGLARGKKQYDKRASIKERDDRREMDRALKR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HYUC_PAEAU
Sequence: MTLQKAQAERIEKEIRELSRFSAEGPGVTRLTYTPEHAAARETLIAAMKAAALSVREDALGNIIGRREGTDPELPAIAVGSHFDSVRNGGMFDGTAGVVCALEAARVMLENGYVNRHPFEFIAIVEEEGARFSSGMLGGRAIAGLVADRELDSLVDEDGVSVRQAATAFGLKPGELQAAARSAADLRAFIELHIEQGPILEQEQIEIGVVTSIVGVRALRVAVKGRSDHAGTTPMHLRQDALVPAALMVREVNRFVNEIADGTVATVGHLTVAPGGGNQVPGEVDFTLDLRSPHEESLRVLIDRISVMVGEVASQAGVAADVDEFFNLSPVQLAPTMVDAVREAASALQFTHRDISSGAGHDSMFIAQVTDVGMVFVPSRAGRSHVPEEWTDFDDLRKGTEVVLRVMKALDR
What is the function of this protein?
Involved in the asymmetric conversion of racemic 5-substituted hydantoins to the corresponding L-amino acids.  Prefers L-carbamoyl-L-tryptophan and N-carbamoyl-L-tyrosine.  Has weaker activity with N-carbamoyl-D,L-phenylalanine and N-carbamoyl-L-thienyalanine.  Carbamoyl derivatives of beta-alanine and charged aliphatic amino acids are not accepted as substrates.
What are the official names of this protein?
N-carbamoyl-L-amino-acid hydrolase, L-N-carbamoylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: BEM3_YEAST
Sequence: MTDNLTTTHGGSTTLELLAQYNDHRSKKDKSIEHIEKGTCSGKERNPSYDEIFTENIKLKLQVQEYETEIESLEKVIDMLQKNREASLEVVLEQVQNDSRDSYVNDQSFVLPPRSAERKAHIKSLNLPIPTLSPPLQQGSDVALETSVTPTVPQIGVTSNTSISRKHLQNMILNDEIEANSSFSSPKIINRSVSSPTKIHSEQLASPAASVTYTTSRITIKSPNKGSKSPLQERLRSPQNPNRMTAVINNHLHSPLKASTSNNLDELTESKSQQLTNDAIQKNDRVYSSITSSAYTTGTPTSAAKSPSSLLEVKEGENKALGFSPASKEKLDDFTQLLDSSFGEEDLVNTDSKDPLSIKSTINESLPPPPAPPTFFSPTSSGNIKNSTPLSSHLASPVILNKKDDNFGAQSAKNLKKPVLTSSLPNLSTKLSTTSQNASLPPNPPVESSSKQKQLGETASIHSTNTLNTFSSTPQGSLKTLRRPHASSVSTVKSVAQSLKSDIPLFVQPEDFGTIQIEVLSTLYRDNEDDLSILIAIIDRKSGKEMFKFSKSIHKVRELDVYMKSHVPDLPLPTLPDRQLFQTLSPTKVDTRKNILNQYYTSIFSVPEFPKNVGLKIAQFISTDTVMTPPMMDDNVKDGSLLLRRPKTLTGNSTWRVRYGILRDDVLQLFDKNQLTETIKLRQSSIELIPNLPEDRFGTRNGFLITEHKKSGLSTSTKYYICTETSKERELWLSAFSDYIDPSQSLSLSSSRNANDTDSASHLSAGTHHSKFGNATISATDTPSYVTDLTQEYNNNNNISNSSNNIANSDGIDSNPSSHSNFLASSSGNAEEEKDSRRAKMRSLFPFKKLTGPASAMNHIGITISNDSDSPTSPDSIIKSPSKKLMEVSSSSNSSTGPHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTLNIPISMLQPFITDFACIFQGGEPVKEEEREKVDIHIPQV
What is the function of this protein?
GTPase-activating protein (GAP) for CDC42 and less efficiently for RHO1.  Negative regulator of the pheromone-response pathway through the STE20 protein kinase.
What are the official names of this protein?
GTPase-activating protein BEM3, Bud emergence protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_STAEQ
Sequence: MDNIAILEALLYTSGDEGLEQKQIIDILDINLNQLEDLVSKYHSHGLTIQRYGSTYVLTTKKETSTYIEQLVKEKSKMKLSQAAMETLSIIAYNQPLTRGDIEMIRGINSDGAVKTLIARGLVEAKDVDHSRSHHLITTDLFLNVFGIENLDALPTTEEDEAEMDEFFSNLVNQKGESNE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: NTPPA_CHRSD
Sequence: MTSSDTPSLRLASASPRRRELLASIGVAVEVAPADIDETPLEDEAPAAYVERLARRKAQVGAEGTTLPTLGSDTAVVVGRRILGKPRDREDAIAMLSALSGTTHEVVTGIAVTGPQGMLSTHVVTRVTLRELQPDEIEAYWRSGEPVDKAGAYAIQGLAAIFVERIEGSHSAVVGLPLFETAKLLTRQGVSLWGERPAVP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGFV1_OXYMI
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLDNEDTLNRNIRAKRETHPVHNLGEYSVCDSISVWVANKTKAMDIKGKPVTVMVDVNLNNHVFKQYFFETKCRNPNPVPSGCRGIDSGHWNSYCTTTQTFVRALTMEGNQASWRFIRIDTACVCVISRKTENF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor 1, v-NGF-1, vNGF-1.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_COPPD
Sequence: MVKYAGLLQFKGTNYAGFQRQKNGTAIQNVLESTLSQINNRATVVRYSGRTDAGVHAWGMPFVFWGREDLSADKWMFILNRMLPKDMRVISVVRTSPEFDPQLSAVAKQYLYCATQERLGPLWDDFFAYLPNLSIETSAVISAARKLVGEHDFKGFSKKGSSVKSTRRKLYEVSVMFTHSRMYFSFVGNGFLYGMVRLMVGTLLQIGWGKQDVNFIDEVLSGNAVANYSAPAQGLHLVKVWLEPDPFLESVKANERDFS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL6_JANMA
Sequence: MSRVGKMPIALPSGAEATITAAQITVKGPLGSLTQSLNGLVNIENDNGTLNFKVANDSREANAMSGTLRALVNNMVNGVTKGFEKKLTLVGVGYRAAAQGDKLNLSLGFSHPVVHQMPQGVKVETPTQTEILIKGIDRQKVGQVAAEVRAYREPEPYKGKGVRYSDEVVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RHCG1_TAKRU
Sequence: MGCVQSFRTLCDRPKNTNVRISLPAVCFVWQIAMIILFGVFIRYDEESDTHWIEHRKKENISSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFHSLDYTDGKIKIGVESLINADFCVAGCLIAYGAVLGKVSPVQLMVLTLFGITLFAVEEYIILSLIHARDAGGSMVIHTFGGYYGLSISWMLYRPNLDQSSNLQGSVYHSDVFAMIGTLFLWMFWPSFNSAITDHGDGQHRAAINTYLALASTVLTTVAISSLFQKHGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFCCGIISTLGYIYLTPFMEKHLKIQDTCGIHNLHAMPGVIGGIVGAITAAAASESVYGKEGLINTFDFEGAFKNMVPTKQGGHQAAGLCVAICFGIGGGIIVGCILRLPIWGDPADDNCFNDEPYWELPEDEESAPPILHYNNHMANKDVVDTNFGMEQN
What is the function of this protein?
Functions as an ammonia transporter.  May play a role in the elimination of ammonia in the gill.
What are the official names of this protein?
Ammonium transporter Rh type C 1, FRhcg1, Rhesus blood group family type C glycoprotein 1, RHCG-1, Rh family type C glycoprotein 1, Rh type C glycoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: FPR2_HUMAN
Sequence: METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
What is the function of this protein?
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236).  Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236).  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236).  The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of pro-inflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339).  Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).  Acts as a receptor for humanin (PubMed:15465011).
What are the official names of this protein?
N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFP.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Associates with Amyloid-beta protein 42, product of APP, at the cell surface and the complex is then rapidly internalized (PubMed:11689470). Also internalized in the presence of humanin (PubMed:15465011).
Protein: Y2560_VIBVY
Sequence: MYPHLTGLGIHDPSQIERYSLRQEAHKDVLKIYFHKQKGEFFAKSVKFKYPRQVKNVLVDSGSHQYKEVTEINRNLTLVIDELNKITKPPKQEDVDIKQKILTDLKHLEKVVASKIAEIEADLEKLK
What are the official names of this protein?
UPF0325 protein VV2560.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: Y2045_STRA3
Sequence: MGFTDETVRFRLDDSNKVEISETLTAVYRSLEEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDL
What are the official names of this protein?
UPF0297 protein gbs2045.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: TIM9_HUMAN
Sequence: MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEETTCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLGQPR
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RSD_YERPA
Sequence: MLNRLESLTQRVGGSNELIDQWLHARKELLVSYCTVIGIKPQKEKHTPLNAKTLENFCHNLVDYLSSGHFHLYDRIIKEVEGASSPKMALTAKIHPALKNNTQTIMAFHDCYTNIEIDDDSCTEYQQALSDIGEALDARFRLEDQLIQWAAESWQAAQLADADKKSQVN
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GASL_CICIN
Sequence: MALVRNNSSNGREPVLSPRSLTSPRGLTSPRPLSVQPTPEPVRPLANFPPSIWADRFISFSLDNSQLEAYANALEEPKEAVKSLITDTTIDANTKLKLIYSVHRLGLSYLYPDEIDAELNKLFEKIDLQYYEQVDLYTIAVQFQVFRHHGYKISSDVFKKFKDSTTGTFTDDVTKDVKGMLSLYESAHLRLHGEDILDEALAFTEAHLKKILTTLEGDLARQVNQVLKRPFHTGMPMVEARLYFITHEEDFSSHESVVKLAKVHFNYLQLQQKEELRLVSQWWKDMQFQQSVPYIRDRVPEIYLWILGLYFEPYYSRARIIATKITLFLVVLDDTYDAYATIDEIRSITDAINRWEISAIDQLPEYIKPFYRILLNEYDDLEKEYSKDGRAFSVHASKQAFQEIARGYLEEAEWLHNGYVATFPEYMKNGLITSAYNVISKSALVGMGAIADEEALAWYETHPKILKASELISRLQDDVMTFQFERKRGQSATGVDAYIKEYNVSEEVAIKELMKMIENAWKDINEGCLKPTEVSVALLTPILNLARMIDVVYKFDDGFTFPGKTLKDYITLLFVSPPPSLEN
What is the function of this protein?
Involved in sesquiterpene lactone biosynthesis.  Produces exclusively (+)-germacrene A.
What are the official names of this protein?
Germacrene A synthase long form, CiGASlo.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RS19_MYCBO
Sequence: MPRSLKKGPFVDEHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTESMVGHKLGEFAPTRTFKGHIKDDRKSKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS19_HALHL
Sequence: MPRSTKKGPFIDHHLLKKVEEANANNSKRPIKTWSRRSVVMPDMVGLTIAIHNGRQHVPVLINENMVGHKLGEFAVTRSFRGHAADKKSKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PDXS_SULTO
Sequence: MRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGGVVMDVTNVTQAEIAEDAGATAVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMAKVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWEFKVPFVNGARNLGEALRRITEGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTVKLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWEDPEIVLEAQKMISESKSMMGIDIKALKPEELLQVRGQ
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: SYW_STAES
Sequence: METLFSGIQPSGIPTIGNYIGALKQFVDVQDDYECFFCIVDQHAITVPQDRLKLRKQIRQLAAIYLATGIDPDKSTLFIQSEVPAHVQAGWMLTTIASIGELERMTQFKDKAQKRADGVPAGLLTYPPLMAADIVIYNTNIVPVGDDQKQHMELTRNLVDRFNSRYNDVLVKPEVRMPKVGGRVMSLQDPTKKMSKSDDNQKNFISLLDEPHVAAKKIKSAVTDSDGIIKFDRENKPGISNLLSIYSGLTNESIKNIESKYEGEGYGKFKGDLSEIVKDFLINFQEKYASFYNSDDLDDILDKGKEKAQKASFKTLKKMEKAMGLGRKR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_MYCLE
Sequence: MDELVTTQSFTATVTGSPRIGPRRELKRATEGYWAKRTSRSELESVASTLRRDMWSDLAAAGLDSVPVNTFSYYDQMLDTAFMLGALPARVAQVSDDLDQYFALARGNNDIKPLEMTKWFDTNYHYLVPEIEPATTFSLNPGKILGELKEALEQRIPSRPVIIGPVTFLLLSKGINGGGAPIQRLEELVGIYCTLLSLLAENGARWVQFDEPALVTDLSPDAPALAEAVYTALGSVSKRPAIYVATYFGNPGASLAGLARTPIEAIGVDFVCGADTSVAAVPELAGKTLVAGIVDGRNIWRTDLESALSKLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDNLRSWLAFGAEKVAEVVVLARALRDGRDAVADEIAASNAAVASRRSDPRLHNGQVRARIDSIVASGTHRGDAAQRRTSQDARLHLPPLPTTTIGSYPQTSAIRKARAALQDAEIDEAEYISRMKKEVADAIKLQEQLGLDVLVHGEPERNDMVQYFAEQLGGFFATQNGWVQSYGSRCVRPPILYGDVSRPHPMTIEWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIAIIQVDEPALRELLPLRRADQDEYLCWAVKAFRLATSGVADSTQIHTHLCYSEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAVGFANSIGPGVYDIHSPRVPSTDEIAKSLRAALKAIPMQRLWVNPDCGLKTRSVDEVSASLQNMVAAARQVRAGA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: SRY_MESST
Sequence: MFRIVNGEDYSPAVQQRNIRDFGKAPSLLWTDNGSSNDRCETGGNGRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMRNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKRPQKSLPADSSVRCSRMHIEETLYPFTYKDGCAKATRSRMESRLSHSQPTNISSSLLPQEHRSSWTSLRHNRVTQAMQTCGRPLLL
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: Y273_ATV
Sequence: MGEKITEEREFQSISEIPEEEIDATNDEEKLADIVENEIEKEIRKSKTRKCKTIENFYYYILRDGKIYPASDYDIEVEKGKRSANDIYAFVETDVTRDFDEFLFDIDYGLPSISDILKFYLEKAGFRIANEVPTPNLKYYIHAVVEFGEDRPQYLAVNIYDIDSLARALRIPQIVEQKLGNKPRTITADEFNDIERIVAEEQPILAGYTYDEALRIPYHYYVDHNNSFKDDALKIAHAYLQLFPTPYQVCYEWKARWFNKIDCLKLERLKPSS
What are the official names of this protein?
Structural protein ORF273.
What are the subcellular locations of this protein?
Virion.
Protein: MUTS2_STRPG
Sequence: MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEASKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTNSERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: SCXX_CENSC
Sequence: MNSLLMITACLVVIGTVWAKEGYLVDVKGCKKNCWKLGDNDYCNRECKWKHIGGSYGYCYGFGCYCEGLPDSTQTWPLPNKTCGKK
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin E1x, CsE1x.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: XYLA_RUEPO
Sequence: MTEFFADIAPVRYEGPDSANPLAFRHYDPDEMVMGKRMEDHLRFAVAYWHSFAWEGGDPFGGQTLIRPWHPQDDMTRAKVKADAAFEMFDILGVPYFCWHDADIRPEAATFAESLRNFEEIIDHFLAKMESRRTRLLWGTANMFSHRRWMAGASTNPDPDVFAYAAATVKTCLDATQRMGGQNYVLWGGREGYETLLNTDMGRELDHMGRFLSMVVDYKHKIGFKGAILVEPKPQEPSKHQYDFDAATCIGFLRKYGLEGEVKLNLEQGHAILAGHSFEHEIAVAASEGMLGSIDMNRNDYQSGWDTDQFPNNVPEVALCYYHILRAGGFTTGGTNFDAKLRRQSLDATDLIAAHVGGMDICARGLKAAAAMIEDGGLETALRDRYAGWDSDHGQGILESDLDSLFARVLAGEIDPQPHSGRQEMLENHVNRFV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.