PharMolix/UniProtQA huggingface dataset:
Protein: NEST_MESAU
Sequence: WREKLEAEVQRQNLYQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLQERREALEQRLEGRWQDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGRSSQASLGFQDPKLKLRFLGTPENQHLGSVLPVLSPTPLPSPLPDTLETPVTAFLKTQEFLQARIPTLASTPIPPMTEAPCLAKAEVRAQDAPLSLLQTQGERQQAPEPLWAKATASVSTGVLTELEEAGGQQPGHFPEDATASAPSLSPHHPVLEAKDGDSTESRGSSIFQEDEGQIWELVEKEAAIELKVESSLAQETQEDGLHTEEIQDSQGPLQKETLEALGEEPLMSLKIQNHETPGKENCNSLRSVDENQGTLKSPEEEKQTLLKSLEEKDVEVEKTLEKGVPELSKPLGKEDPRIEDQELMSPEGTLETLSFIGKRNEEVVRSSEEENIESLAAFKKESQHPLGCPEEEIQRVERLIEKEGQESLSSPEEEDQETDRPLEKENGEPLKPVEEEDQLFETLIEKEGQESLSSPEEEDQETDRPLEKEEDQLVERLVEKEGQESLSSPEEEDQETDRPLEKENGEPLKPVEEEDQLFETLIEKEGQESLSSPEEEDQETDRPLEKEEDQLVERLVEKEGQESLSSPEEEDQETDRPLEKEEDQLVETLIEKQGQECLSSPEEEDQETDRPLEKEEDQRVERLIEKEGQESLSSPEEEDQETYRLLEKENGEPLKPVEEEDQRVERLIEKEDQESLSSLKEEDQRIVKTLERENWESLRSLDENLDTVMPLESKNQKPLKSLEAEEEQRIVKPLEKVSQDSIGSLEKENVELLRSLEDDQITESLLKKGTQESLESHEDRNQETQDPQRFLEEEGQGIVKQLEKENQGFLGSLEEEKVVKRSLERENHEPLSSVEKDWVTESLLERESQDSGKSLEGQEAFRCLGKEDPESLQFPEVQDQEIQRSLQQETQQTLGALGDEQMASEPPEKVGPELLKFLGNGQEIVRSLEEQNQESLVSVKETSVETAKSSDMEDIEPLKSADEDLEIINSAGAQESLWSMEVTRETTRPLEKEVQESLGFVGGNQEILRPLERGNEELGSLGKWNLEAVDSPEAVEEGRQPLGEEACLEMGEHQEPPRSLGEVEQGLPGSGNQQKWEDRAVENAAADQGPTLGRTGIESEDEAELPLSGQGEKEEDAEERELQLDAMGEAWSLASSEPQEPRVPSEGGSAGAPQGLEGQSEQVGVLGVPVGQGMPEVTEPLLQEDVAQAGKRDPIELTLGSDAATRAGLGLEQEVAGSGGSRHLAREEAIHPSLGEESVEAKIAHDLEGPGKEPKEAGALESEISELPRTSSDVLESKGCKQSEPVLGWAVEEASVEASDHEGSDAPEPRPSETEGDEGAQAALAPPGPKLMEPCSPTPILKDAYEWQPQAEGTRETGRQLEGGSASLERVEDEQEFGLGGIPEGLQDWEESREESEADELGETLPDSTPLGLYLRSPTSPKWDQAGEQRLSPQGEARKEGWGPAVPAAQGLSNPPGEEERGHDSDLSSEEFEDLGTEASLLPGLPKEVADHLGQVPPGPEPECWDQGGESDGFADEEESGEEGEEEEHEDGTESGAQWWGSGPSKVQHVTQRGDLQEHESVGISGPWDDGWRGAAAGISVTGLETESQDSAEPSGSEVSESVSSEGEDQAPDHLDTPQGVTNVVPGAGDTFGISGQAPNLESEHMNGRLENGLEQSEGQGVLDRHQDQGHPSQQQEVGALKAPLLGSPVHRGPSQSLEFPLSGADRDSWSSGED
What is the function of this protein?
Required for brain and eye development.  Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division.  Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
What are the official names of this protein?
Nestin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MRAY_ANAMF
Sequence: MFSPIGKVAQPYFCSFLLSTILGFVIAPRTIAALKNIQKGRNPVRSCFPAAHLAKKSGIPSMGGVIILLPCILSTAIFGDLHDRDIWVILTTMVAFAILGGVDDYLKFTRQNPQGISLEAKLFAQLLIASAALIFLSYTSDSFTSTHIFSKGLIDLGWAYMPFAYIVVVGSSNSVNLTDGLDGLATLPIITSTAILGIIGHLSLQFGAEPPGVVGANIPIFCSALVGSALSFLWFNAHPAQVFMGDLGSLSLGASLGLMSVMLKCEFIYAISGCIFVAEAISSMAQVAYCKLTKGRKIFLVAPIHHHFEKAGLKEATIVTRAWVIAMVSFVVSLAAIIYIYR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAND_GEOUR
Sequence: MDRKMLKSKIHRATVTGADLHYEGSITIDKDLMEAADIIPYEAVCIWDVDNGSRFETYAIEGERGSGVICINGAAARMVAPKDLVIIASFVNMNNEEALKHEPKLVFVDDQNRMLPARKEVAGQGTLKKVAW
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT10C_CONAO
Sequence: ACCVYKICYPC
What are the official names of this protein?
Conotoxin ar5c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALLC_ACIB3
Sequence: MATLHAPAFELPEILNTKTNLADARIGAQVIECSDDFFAEAKRMLQFEAPIFVEDKFDDHGKWMDGWETRRKRHAGYDWCIVKLGVSGKISALDIDTTFFTGNYPASASLEACYAPNGDLTGVTWQSILENTELGPSQHHIFMVNNDAIFTHIRLNIFPDGGVARLRVYGDVHIQVTDHEQTLDLLALENGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGYDWCILALGKSGKIEKIEIDTAHFKGNFPAEVSIQAVYLENATDAQLIPQSMFWSYLLEAQPMQMDHIHEYVNEILKHEKISHIRINMIPDGGISRVRLWGKIAKS
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: EFP_UREU1
Sequence: MATIIQAKDLRAGHTFLYKGSIYQVIENSFNKTAMREGIVKCKVKNLRTGAITVEVLTGEKVEQAIIEKSKMTFSYDDGSGYVFMDNETYEQISIPYNQLSWEKNFIEEGTEVSVMRYDGELMGVSLPDQLVVTIVEAEEAVQGNSVQNATKRAWLASKWEFQVPQFIKSGEKVIINPSNGQYVGRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_THEP1
Sequence: MKQEKLSLNDVLIRPIITEKALILREQRKYVFEVNPLANKNLVKEAVEKLFNVKVEKVNILNMKPKPKRRGIFEGKTRSWKKAVVTLKEGYTIKELEGEH
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: LARC_CLOK5
Sequence: MKILYYDCFCGISGDMNLAALIDLGVPKEYLMEELSKVNLNSEYEMKIERSVKLGITGTRVDVKLNESSHGEEEHGHDHYHHHRKLKDIEKIINSSHLSDKVKNISLGMFMKIAEAEAKIHGKSLCEVHFHEVGAIDSIVDLVGAAICIDYLKVDRIIASPVQVGGGFVECSHGIIPVPAPATTEILKNIPISTGIVQFETTTPTGAAILAVNVEEFTSKIDFSIEKIGYGIGHRDLEIPNVLRVYLGEQERSEKVEEQYILETNIDDMNPEFYEYVQERLFEVGALDVFKTPIYMKKGRPGINLSVLISEKGEKDVLDVIFEETTSIGVRKHKVEKIMLNRDFSKVKTEYGDITVKKSYYKGKLVKYKPEYEECKAIAKEKNISIDKIYKVVYRQDLN
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: HOA_ECO8A
Sequence: MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PYRB_CLOPS
Sequence: MLKNKHLLDPSDFTIEEFDEIFKLAHQIMTNPKEYQNICNGKILATLFYEPSTRTRLSFESAMIRLGGQVIGFSEPNSSSVSKGESLRDTIKTVNCYADLIAMRHPLEGSAKVASMYSDIPVINAGDGGHQHPTQTLTDLLTIKEYKGNLEGNTIALCGDLKFGRTVHSLIKALSRYKNNKFILISPIELRIPNYIREQILEKNNIEYKEITSLEEGIKEADILYMTRIQRERFVDQSEYERLKDVYVLDEAKMKGAKEDMMVLHPLPRVNEIAYEVDEDSRAFYFKQAKCGMYVRMALMAKLLGEA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ATPL_SALTY
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_CLOP1
Sequence: MAKVQYMGTGRRKKSVARVRLVPGEGRVIVNNREIETYFGLETLRVVVNQPLVLTETKDKYDVLVNVHGGGLSGQAGAIRHGISRALLKADENLRPELKKAGFLTRDPRMVERKKCGLKKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HVCN1_DANRE
Sequence: MSRYLKHFTAVGDNKSAVPTWHEEDTSHHVTTLHDAPDGLEVSTGQHLGQLSFRDSLRKLYSTERFQIVVVCLVVLDAIFVLCELLIDLSIIEADHHRIAPQVFHYLSLALLTFFMVELAGKIFAYRLEFLHHKFEVFDGIVVVVSFILDIIYISKEDAFDAMGLLILLRLWRVARIINGILVSVQNRANHRVEKLKEINESLVHQVNELKEQNTKMDQENVRLRALLKDHSIDF
What is the function of this protein?
Mediates the voltage-dependent proton permeability of excitable membranes.  Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity).
What are the official names of this protein?
Voltage-gated hydrogen channel 1, Hydrogen voltage-gated channel 1, HV1.
What is the protein family that this protein belongs to?
Belongs to the hydrogen channel family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ATP6_BDEBA
Sequence: MSFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFELLTEMTSGLADMVIGEHGKHYIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVLMFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVSHIVRPFSLGLRLANVMMGDHTVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPB_SHISS
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RL7_CAMC1
Sequence: MAITKEDVLEFISNLSVLELSELVKEFEEKFGVSAAPVMVAGGAVAAGGAAAAEEKTEFNIVLVDSGDKKINVIKVVRALTGLGLKEAKDAVEGTPSVLKEGVSKDEAEAAKKELEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PHNS2_DESVH
Sequence: MSYTTRIPAKLLARQAEDGRMTRREFMKFCGIVAVAMGMGPGFAPAVAEALQAKGRPSVVYMHGAECTGCTEGLLRSIDPFIDILMMEVISLDYCETVMAAAGRAAHHALEDALRNPAGYVCTIEGAIPTRKGGVYGQVGGETMLSLFSRVASGAKAVIAMGTCASFGGIQAAAPNPSGAIGVREALAPFGIQPINIAGCPPNPVNYIGTVVHLLTKGMPELDSAGRPKMFYGTTVHDQCERRKHFNADEFAPGFESKEAREGWCLHKLGCRGPYTYNNCPTAQFNQVNWPVRAGAPCIGCSEPGFWDALAPFNKDVRQKSDKA
What are the official names of this protein?
Periplasmic [NiFe] hydrogenase small subunit 2, NiFe hydrogenlyase small chain 2.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SPB1_DEBHA
Sequence: MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASQLCPINSLIIGVDIVPIKALPNCITFQSDITTEDCRSQLRGHMKTWKADTVLHDGAPNVGLGWVQDAFTQSHLTLQALKLAVENLNTGGTFVTKIFRSRDYNNLMWVFQQLFEKVEATKPPASRNVSAEIFVVCKGYKSPKKMDPRLLDPREVFEELPTGPDNNEAKIFNPEKKVRRRQGYEEGDYTLFHEMPLLEFIKNEDPINTLGTLNKLSEPPQDDHEWKILKKSKLCTPELLECIKDLKVLGRKDFKHLLKFRKQARDLLGLDAKEETQEIEVEPLTEDQQIEKELQELTEKQKQKARKAKKQSNEIKQKEIQRSQMNMLTDMNIGIEAAQIGAESLFNLKTAIKTGQLEKLSKGKKKMIFNDEEIMKDNDINFDEEADANSEDEIDELEAQLDDMYNSYQNRRAERDANYRAKKLRGDVDDEGWEGIESDKEGSDKETEANDYEMESESDSDDDEHIQRIADQRKKELSKNAKVFFASNSIFGELGDEALLEEMNKKEAKTNQVTNENAVGHANDISNKPEQMEVDSSDSENDVSDDSDFEIVPNAPDEELSDSDSDNENDVSRKYSKAKDQQSKVDIATVEAMTLAHQVALGHKNKHDLVNEGIHKYSFRDHDDLPEWFVDDEKRNSKIVKPITKEAALAIKEKQKQLNARPIKKVLEAQGRKKLRALKRLEKLKKKSDMINEDSAKSERDKADEIQKLMKKLTKKQKTKPKATLVVARGSNRGLSGRPKGVKGKYKMVDGVMKNEQRALKRIAKKHKK
What is the function of this protein?
Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
AdoMet-dependent rRNA methyltransferase SPB1, 2'-O-ribose RNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYDND_FRATT
Sequence: MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVADSLRSEFVIKAEGVVNLRPEGQENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGEDVKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLDIETPFLTKATPEGARDYLVPSRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFIDEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKEDMQNEEFKVFSGPANDPQSRVIALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSLSQGKEGLQSPIVKNISEETLFKVIDKTSAKEGDLLFFGAGKAKIVNDSMGALRAKIGEDLDLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVINGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGIDRLIMLLTGTTNIRDVIAFPKTQTASCLMTEAPSTVSLEQLNELGIAVKKEER
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_FRAP2
Sequence: MSDINLKIGLAEMLKGGVIMDVVNAEQAEIAQQAGAVAVMALERVPADIRKDGGIARMSDPKLIKEIMSVTSIPVMAKARIGHFVEAQILESLGVDFIDESEVLSPADDLNHIAKDNFKVPFVCGCTNLGEALRRIGEGAALIRTKGEAGTGNIVEAVRQLRQVNKDINYIKGADQSELMAIAKNMQAPYDLVKYVHKNGKLPVPNFSAGGVATPADAALMMQLGAESVFVGSGIFKSADPLKRAKAIVSAVTYYNDPKILAEVSEDLGEPMTGINCDFEKFSQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y1688_BACC1
Sequence: MKVIAVTGYKPFELGIFKNDHPGVECIKKALRRKLTAFVEDGLEWVIISGQLGVELWAAEVVFEIQVEYPDLKLAVFTPFLEQEEGWKEDNREYYEFILSQADHVDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVEAAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BCE_1688.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: LIPB_IDILO
Sequence: MNDTLIIRELGRQPYEPVWHAMQEFTDQRDEHTADELWVVEHDPVFTQGQAGKAEHILAPGDIPVIQVDRGGQVTYHGPGQLVIYFLLNIRRLNYGVRQLVNHIENTVIETLSDYEIDAKARRDAPGVYVDTDKICSLGLRIRKGCSFHGLALNVNMDMEPFSRINPCGLSGIKMIQTKDLNGPDSFSEAADAVIKHFTSSLSYSNILQQTGLAQDYVKAS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS1_SCHPO
Sequence: MSVDSLVSCLEQLITDDLKLVEHQEVSNGATWASALQSTKDVPSHALTKTIVLKPKTAKSQTVVPIILAALETTSTPSGIAAKAVGSKEARMAAADLVEEVFGIPPTDVGIFSVNKENASKVHVVLDAALIQHNGLLAFHPSSSAKTVFVSPAAVQTYLKSVGVNPIIVDFSAPGSATAPSKPAAQKKKAEPSKNDAAIENAALIGITVRKDADFPNWYQQVLTKSDMIEYYDISGCYILKPWSYSIWEAIQGWFDKEIKKLGVRNGYFPLFVSSKVLEKEKDHVEGFAPEVAWVTRAGTSELDEPIAIRPTSETVMYPYYAKWIRSHRDLPLKLNQWNSVVRWEFKNPQPFLRTREFLWQEGHTAHMTLEGATEEVHQILDLYARIYTDLLAVPVIKGVKSENEKFAGGMFTTTVEGYIPTTGRGIQGATSHCLGQNFSKMFNIVVEDPNAEIGPTGERPKLFVWQNSWGLSTRTIGVAVMVHGDDKGLKLPPAIALVQSVVVPCGITNKTTDQERNEIEGFCSKLADRLNAADIRTEADLRAYTPGYKFSHWEMKGVPLRLEYGPNDAKKNQVTAVRRDTFEKIPVPLNNLEKGVSDLLAKIQTNMYETAKAERDAHVVKVKEWADFVPALNKKNIVMIPWCNTTECEKEIKKNSARQVNGDEPEDEKAPSMGAKSLCIPLEQPSGEDAIIEGTTKCAGCGNLAKVWGLFGRSY
What are the official names of this protein?
Putative proline--tRNA ligase C19C7.06, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: ESXH_MYCBO
Sequence: MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
What are the official names of this protein?
ESAT-6-like protein EsxH, 10 kDa antigen CFP7, CFP-7, Low molecular weight protein antigen 7, Protein TB10.4.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: ADEC_RUBXD
Sequence: MEERGRRKPLYEMTRELAATARGDLPATLVIRDGTLVSVTSGEVLPGMSVAVRGPRIAYVGPDAGHTVGPQTTVIDAAGRYIAPGFLDGHCHIESSQITVTQFARAVLPLGTTGGFFDAHEITNVLGLRGLRLMLDEARSTPLAAYLEVASCVPSTSTELETPGAVIGPEEVAEALSWGEDVIALGEVMNFPGVVFGDERMHAEISAALRAGKIADGHFCWPPDDHRLAAYAASGISGCHEGTTPEDTLWRLRQGMYAKLRRGSAWHDVAATIKAHTERGLDPRRILLVTDDRSPESLLEEGHMDFVVRHAIAQGVNPVTAFQMATLNPAERFRVSHDVGSVTPGRYADILLLEGDLAEVRVSLTVAAGEVVAEGGRMVAELEPYDYPAFCLDTVRVAGGLGPEDFDIPAPGGGERARVRAIRVVENHVETRGEWVELPVEGGLVRLDPRKDVCKLFVIERHGRGGGRGAGFVTGLGFERPAALASTVAHDSHNLMVLGNSEELMSRAAREVVAARGGVAVAVGGETAVLPLPVAGLMSPEPYEEVARLSREIGRALRSAGCRMNYAFMTISLLALVVLPELHLSDRGLVEVGEEGFRLVGLAAEG
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: YCIZ_SALDC
Sequence: MSDIEAQRIAARIDTVLDILVAGDYHSAINNLEILRAELLDQVKDGISPSQAPGSPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: RL3_SYNSC
Sequence: MSIGILGKKLGMSQFFDEQGRAVPVTLIEAGPCRITQLKNDDTDGYSAVQIGFGETREKLINKPAQGHLNKSGEGLLRHLREYRVDSVEGLELGGAITVGDFEAGQKVDVSGDTVGRGFAGYQKRHGFSRGPMTHGSKNHREPGSTGAGTTPGRIYPGKRMAGRYGGKKITTRGLTILKVDSEHNLLVVKGSVPGKPGALLNIRPALRVGAKPANGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TOR1A_CRICR
Sequence: AECCGQKRSLSREALQKDLDDKLFGQHLAKKVILNAVSGFLSNPKPKKPLTLSLHGWTGTGKNFASKIIAENIYEGGLNSDYVHLFVATLHFPHASNVTLYKDQLQMWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDVVDEVSYQKAIFIFLSNAGAERITDVALDFWKSGKQREEIKLRDMEHALAVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYEVDEDIISKVAEEMTFFPKEERVFSDKGC
What is the function of this protein?
Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates.  Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN).  In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity.  Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission.  In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding.  May have a redundant function with TOR1B in non-neural tissues (By similarity).
What are the official names of this protein?
Torsin-1A, Dystonia 1 protein, Torsin ATPase 1, Torsin family 1 member A.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Nucleus membrane; Peripheral membrane protein. Cell projection, growth cone. Cytoplasmic vesicle membrane. Synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Mainly located in the lumen of the endoplasmic reticulum.Peripherally associated with the inner face of the ER membrane, probably mediated by the interaction with TOR1AIP1. The association with nucleus membrane is mediated by the interaction with TOR1AIP2 (By similarity).
Protein: ZAPB_ACTP7
Sequence: MSLPILDQLEEKIKQAVETIQLLQLEVEELKEKNTTVEQEKETLRQEYEQLKSEQQSFQDRLRSLLGQIDNV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.