PharMolix/UniProtQA huggingface dataset:
Protein: COAA_STRCO
Sequence: MISPVPSIPRSAHRQRPEATPYVDLTRPEWSALRDKTPLPLTAEEVEKLRGLGDVIDLDEVRDIYLPLSRLLNLYVGATDGLRGALNTFLGEQGSQSGTPFVIGVAGSVAVGKSTVARLLQALLSRWPEHPRVELVTTDGFLLPTRELEARGLMSRKGFPESYDRRALTRFVADIKAGKAEVTAPVYSHLIYDIVPDQRLVVRRPDILIVEGLNVLQPALPGKDGRTRVGLADYFDFSVYVDARTEDIERWYLNRFRKLRATAFQNPSSYFRKYTQVSEEEALDYARTTWRTINKPNLVENVAPTRGRATLVLRKGPDHKVQRLSLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_ECO45
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMTELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_BARQU
Sequence: MNESLVELSAYLKNKLGDKLEETILAFGELTIVSRLDAITGVLMFVRDDSRCQFINLTDISGVDYPSRDKRFDVSYQLLAPRHNLRLRIKVRTDENTPVASACSIYPGAEWYEREAYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDNEAKRVIYEPVVLRQEMRNFDFLSPWEGAQYVLPCNEKAEGEK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SECB_SALNS
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD_SHEDO
Sequence: MATPHINAVPGAFAETMLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSASIYAYELIKEYGVKNLIRVGTCGAISTDVKVRDVIIAMGACTDSKVNRLRFKDHDFAAIADYSLLSAVVDSAKEHGTQIRVGNVFSADLFYTPDPQMFDVMEKMGVLGVEMEAAGLYGVAHELGAKALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAITL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RL1_STRP3
Sequence: MAKKSKQMLAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TPIS_CHRVO
Sequence: MSGKLVIGNWKMNTRGDSARQLAAALLADGQTNREGVGIAAPAVYLAALAEQLKGGKIALSSQDVSRFAADGAFTGEVSAAMLADVGCRYALVGHSERRQYFREDNAALLAKMRNAIAAGVTPVLCVGETLAQREAGDYLNVVREQLAILSDIADGEYVVAYEPVWAIGTGKVASLEQIAEIHAFIKNWCLQNAGGSAKIRVLYGGSVKAENAEAILATENVDGALVGGASLDADSFRVICQAAGKMI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_DESRM
Sequence: MLELNNFDSIRIGLASPDKIRQWSSGEVKKPETINYRTLKPERDGLFCERIFGPTRDWECHCGKYKRVRYKGVVCDRCGVEVTRSKVRRERLGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEKVLYFVSYIVIEPGDTPLLKKQLLTETEYREYRDKFGNNFKAGMGAEAIKVLLVEINLEELARELRQELKEVSGQRKIRAIRRLEVVEAFKKSGNRPEWMIMDVVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPRLKMHQCGLPKEMALELFKPFVMKKLVNDGHAHNIKSAKRMVERVRPEVWDVLEDVIKEHPVMLNRAPTLHRLGIQAFEPVLVEGRAIKIHPMVCTAYNADFDGDQMAVHVPLSAEAQAEARLLMLAANNILNPKDGKPVASPTQDMVLGSYYLTMDRDGDLGEGLIFKDEQEAMLAYDNKQVSLQAKITVRRKNGERLQTTVGRIIFNEVIPEELGYINKVCDKKTLSKIVADCYRRLGNAHTAELLDGIKELGYKYSTRAGITIGVPDITIPEAKKEILAKAEEQVNKIETQFRRGLITEDERYRKVIGIWNDATDKVTKALMATLDKFNNVYMMATSGARGNIQQIRQLAGMRGLMADPSGRIIDLPIKANFREGLTVLEYFISTHGARKGLADTALRTADSGYLTRRLVDVAQDVIVREDDCGTTEGIEVREIRDGTEGIEKLHERLEGRVPMEVVVHPETGEVLISQEQVDNHQVMTEEQAQAIEDAGIEKVKIRSVITCKTRYGVCKHCYGKNLATGGNIDIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVEELFEARRPKGQAIVAEEDGSIAIREVKGRREIEITKDNGEKNVYAVPFGARIKVKEGQRIEAGDELTEGSVNPHDLLKIKGPAGVQVYLLQEVQRVYRLQGVEINDKHIEVMIRQMLRKVKIEEAGDTELLPGGLIDIFEFEEENRKAVEQGGEPAVAKPVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKMDPLLGLKENVIIGKLVPAGTGMSRYRNIEVLEEGQPFLEEDRDILLPERDRDYNFLSDEEKIDFDLTLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ATPF1_NITMU
Sequence: MNINFTLISQAMAFAIFIWFTVRFVWPPLMRAIENRQKTIAEGLAAGERGKRELELASQRSGDVVREAKQRASDIIAQAEKRAAEIVDEAKVAAREEGDRILVGAKAEVEQEVFRAKEVLRQQVAGLALAGAAKILRREVDEKAHAELLASLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y675_RALSO
Sequence: MASPDAPINLTNQFLIAMPGMADPTFSGTVVYLCEHNERGALGLVINRPIDIDLATLFDKIDLKLEIHPLAEQPVYYGGPVQTERGFVLHDAMGSYSSSLTVPGGLEMTTSKDVLEAVARGGGPQRFILTLGYAGWSAGQLEEEIGRNGWLTVQADPEIIFNVPAEERFAAALRLLGINPAMLSGEAGHA
What are the official names of this protein?
UPF0301 protein RSc0675.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: CLPB_CHLMU
Sequence: MEKFSDAVSEALEKAFELAKDAKHSYVTENHLLKSLLQNPGSLFCLVIKDVHGNLGLLTSAVDDALHREPTVVEGAAIPKPSPSLQQLLLNAQEEARSMGDEYLSGDHLLLAFWKTTKEPFASWRKTVKTSPEALKELIIKLRQGSRMDSPSAEENLKGLEKYCKNLTILAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRIVQGDVPESLKDKHLYVLDMGALIAGAKYRGEFEERLKSVLKGVEASEGACILFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNEYQKYIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVVLSYRYITDRFLPDKAIDLIDEAASLIRMQIGSLPLPIDEKERELSALIVKQEAIKREQAPAYQEEANEMQKAIDRVKEELAALRLRWDEEKGLIAGLKEKKNSLENLKFAEEEAERTADYNRVAELRYSLIPSLEKEIRLAEEALNQRDGRLLQEEVDERLIAQVVANWTGIPVQKMLEGESEKLLVLEESLEERVVGQPFAITAVSDSIRSARVGLSDPQRPLGVFLFLGPTGVGKTELAKALAELLFNKEEAMIRFDMTEYMEKHSVSKLIGSPPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVFNILLQIFDDGILTDSKKRKVNCKNALFIMTSNIGSQELADYCAKKGTIVDKEAVLSVVAPALKNYFSPEFINRIDEILPFVPLTTEDIVKIVGIQMNRVALRLLERRISLTWDDSVVLFLSEQGYDGAFGARPLKRLIQQKVVTMLSKALLKGDIKSGMSVELTMAKDVVVFKTKTNSVV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y194_STRSY
Sequence: MMNMQNMMRQAQKLQKQMEKSQAELAATQFTGSSVQDLVTATFTGDKKLVSIDFKADVVDADDLETLQEMTIQAVNAALTKVDEATQKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SSU05_0194.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: THSA_SACS2
Sequence: MAAPVLLLKEGTSRTTGRDALRNNILAAKTLAEMLRSSLGPKGLDKMLIDSFGDVTITNDGATIVKDMEIQHPAAKLLVEAAKAQDAEVGDGTTSAVVLAGALLEKAESLLDQNIHPTIIIEGYKKAYNKALELLPQLGTRIDIKDLNSSVARDTLRKIAFTTLASKFIAEGAELNKIIDMVIDAIVNVAEPLPNGGYNVSLDLIKIDKKKGGSIEDSVLVKGLVLDKEVVHPGMPRRVTKAKIAVLDAALEVEKPEISAKISITSPEQIKAFLDEESKYLKDMVDKLASIGANVVICQKGIDDIAQHFLAKKGILAVRRVKRSDIEKLEKALGARIISSIKDATPEDLGYAELVEERRVGNDKMVFIEGAKNLKAVNILLRGSNDMALDEAERSINDALHALRNILLEPVILPGGGAIELELAMKLREYARSVGGKEQLAIEAFADALEEIPLILAETAGLEAISSLMDLRARHAKGLSNTGVDVIGGKIVDDVYALNIIEPIRVKSQVLKSATEAATAILKIDDLIAAAPLKSEKKGGEGSKEESGGEGGSTPSLGD
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermophilic factor 55 alpha, TF55-alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: CAIE_ECOBW
Sequence: MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCLIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRNVSDDELHWKRLNTKEYQDLVGRCHVSLHETQPLRQMEENRPRLQGTTDVTPKR
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: NADM_METHJ
Sequence: MIRALYIGRFQPYHNGHHYVINQIAQEADELIIGIGSAQMSHEPADPFTAGERVLMITGALQDLHKPLYVIPLEDINRNVLWVSHVRAMTPPFHRIYSGNPLVIRLFHEAGIEVLSPAMYERATLSGTKIRDLIACDKPWEDFVPPAVVRVIQEIDGISRIRALNQDDGDCPGR
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_ALBFT
Sequence: MTHTTVLLNEAVDALFCNPDATADASATGAQVYVDATFGRGGHSRLILSRMTPTDRLIAFDKDAEALVEAGNIHDSRFSIRHQGFSHLDELPPASVAGVLLDLGISSPQIDNPARGFSFRFEGPLDMRMDTTRGISVAQWLANAETEKIAEVIRDYGEERFAGPIAKAIVARRQERGPISSTTELAQLVADTVKTREPGQNPATRTFQAFRIFINAELEELQQALAASLLVLAPGGRLVVISFHSLEDRIVKQFIAQHSRDVYDRRAPFAPPKVMQLKALARLRPSAAEVSANPRARSAIMRVAQRTAS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECE_HALWD
Sequence: MDVKIELSSYVRVLKLASTPSWNEFSQIGLIAGAGIVFVGFLGFLIFAIMTLLPGGV
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYR_RICRS
Sequence: MNIFNQLKQDIIVASKQLYNNQAIANTATIDIPKDSFNGDLSSNVAMIIAAKESIAPREVALKFKEVLITLPYIASIEIAGPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVSYSVTKEYYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYDERFKIIKSFAVEKMLDLNRKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLESMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKADGSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNNEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFESGKYDLSLLSSEEEIEIIKLLVSWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSEYRFVIESNKELTLARLALASAIQKVIASGLEVIGVEPMNKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_RICCN
Sequence: MSFYESVFIIRQDVSLNDIDKIVDDFAKIIKDNNGTIIKKEYWGLRTLAYKIGNNKKGHYYFLGLDITGNVKEELERKMKLNENIIRFLTIQADSISSEPSPILKNQSTENTPVIDVTINN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: LET60_CAEEL
Sequence: MTEYKLVVVGDGGVGKSALTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNEAKSFENVANYREQIRRVKDSDDVPMVLVGNKCDLSSRSVDFRTVSETAKGYGIPNVDTSAKTRMGVDEAFYTLVREIRKHRERHDNNKPQKKKKCQIM
What is the function of this protein?
The level of let-60 controls the switch between vulval and hypodermal cell fates during C. elegans vulval induction (PubMed:2257629, PubMed:2123303, PubMed:24929033, PubMed:28135265, PubMed:20230814, PubMed:32053105, PubMed:23103556).  May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1 (PubMed:10608844).  May induce nuclear condensation (PubMed:23103556).
What are the official names of this protein?
Ras protein let-60, Abnormal cell lineage protein 34, Lethal protein 60.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: H4_HUMAN
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: COR2_PAPSO
Sequence: MEIGGVPVVTLSSGRGMPILGMGTAENNLQGSERVKLAILKAIEVGYRHFDTAFVYQTEGSLGEAVAEALQNGLIKSRDELFITSKLWCADAYPDHVLPALQNSLRNLKLEYLDLYLIHWPVSLKPGKFVHPIPKDEIFPIDYKSVWAAMEKCQMLGLTKSIGVSNFSCKKLHYLMATANIPPAVNQVEMNPIWQQQKLRDYCKTNNIMVTAYSPLGAKGTMWGSSGVMDSEVLNQISQVRGKSVAQVSLRWVYEQGASLLVKSFNEERMKENLKIFDWELSPEDLKNISELPQRRVSTGDPFVSINGPFKSVEELWDDEV
What are the official names of this protein?
Non-functional NADPH-dependent codeinone reductase 2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex.
Protein: G6PI_HELPS
Sequence: MLTQLKTYPKLLKHYEEIKEVHMRDWFSKDKERASRYFLQFESLSLDYSKNRLNDTTLKLLFELANDCSLKEKIEAMFKGEKINTTEKRAVLHTALRSLNDTEILLDNMEVLKSIRSVLKRMRAFSDSVRSGKRLGYTNQVITDIVNIGIGGSDLGALMVCTALKRYAHPRLKMHFVSNVDGTQILDVLEKLNPASTLFIVASKTFSTQETLTNALTARKWFVERSGDEKHIAKHFVAVSTNKEAVQQFGIDEHNMFEFWDFVGGRYSLWSAIGLSIMIYLGKKNFNALLKGAYLMDEHFRNAPFESNLPVLMGLIGVWYINFFQSKSHLIAPYDQYLRHFPKFIQQLDMESNGKRISKKGEIIPYDTCPVVWGDMGINAQHAFFQLLHQGTHLIPIDFIASLDKKPNAKGHHEILFSNVLAQAQAFMKGKSYEEALGELLFKGLDKDEAKDLAHHRVFFGNRPSNILLLEKISPSNIGALVALYEHKVFVQGVIWDINSFDQWGVELGKELAVPILQELEGHKSNAYFDSSTKRLIELYKNYNQ
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELOV6_DROME
Sequence: MINMDISVTPNYSYIFDFENDFIHQRTRKWMLENWTWVFYYCGIYMLVIFGGQHFMQNRPRFQLRGPLIIWNTLLAMFSIMGAARTAPELIHVLRHYGLFHSVCVPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQPLIFLHWYHHITVLIYSWFSYTEYTSSARWFIVMNYCVHSVMYSYYALKAARFNPPRFISMIITSLQLAQMIIGCAINVWANGFLKTHGTSSCHISQRNINLSIAMYSSYFVLFARFFYKAYLAPGGHKSRRMAASLAAQNVVKQSSSPQQASESSKFIGAGEDQAAYLRKAKAQ
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:26214738).  This process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle (PubMed:26214738).  Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs (By similarity).  Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree (By similarity).  May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity).
What are the official names of this protein?
Elongation of very long chain fatty acids protein 6, ELOVL6, Neighbor of abl, Very-long-chain 3-oxoacyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL6 subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RASK_HUMAN
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621).  Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838).  Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
What are the official names of this protein?
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endomembrane system. Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 2B]: Cell membrane; Lipid-anchor.
Protein: COAA_ECOLI
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase, Rts protein.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_PECAS
Sequence: MTEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGINAHAVDTRDFPVTTLKEEGFTNVFIALHGRGGEDGTLQGVLEFLGLPYTGSGVMASALTMDKLRTKQVWQAVGLPVSPYVALDRRQYLDTEANTLLAQFTHLGLPLIVKPSREGSSVGMSKVNTLSDLPAALEEAFRHDDDVLVEKWLSGPEYTVAILGDEVLPSIRIQPAGTFYDYEAKYLSDDTQYFCPSGLSDEQEQALAALAMAAYRAVDCSGWGRVDFMLDSDDAFYLLEVNTSPGMTSHSLVPMAARQRGLTFSQLVVKILELAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_BURL3
Sequence: MHLEHLVTEQPNGQSANLDALGIPDALALMNREDAGIAARVAHALPAIASGVTVIADALRAGGRLIYIGAGNSGRIGYLDALECQPTFGTQPGEIIGIVAGGFAGITESVEDSDTLGRQDLDAAGLARGDVVVGLTASGRTPYVLGALRHARDTGCRTIAVACNVGSEAAALADVAIEVDCGPEVLTGSTRLKAGTAQKMICNMLSTISMVALGKTYGNLMVDVQVHNHKLRRRAIGIVSQAAGVPTDVAERALEQAGDRPRIAILMLCAGVDRAGAERLADAAGGSIRKALATLAPSTRA
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.