PharMolix/UniProtQA huggingface dataset:
Protein: TRPF_PSEPF
Sequence: MSAVRSKICGITRIEDALAAVEAGADAIGFVFYAKSPRAVTVQQARSIIAALPPFVTTVGLFVNASRCELGEILDAVPLDLLQFHGDETAAECEGWHRPYIKALRVKAGDNIAAACDAYPSASGVLLDTYVEGVPGGTGEAFDWSLIPQGLSKPLILAGGLTPENVADAIARVRPYAVDVSGGVEASKGIKDHAKIRAFINAVR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: MPTE_PYRFU
Sequence: MKWEEWKPFYERIVKEMGYSIEEDRRAAELLRDILMENDNYIIKEELNSIIMQKVYVFGAGPNLEEALKKGDFKDGTKIAADGATSALLEYGITPDVVVTDLDGRIRDLLEASRKAVMVVHAHGDNMDKLPLVVEFPLVLGTCQTEPLDIVYNFGGFTDGDRAAFLAEEMGAKEIVLVGFDFSGIVGKWSKPWLRDHTPAWESKMKKLKFARELLEWLKNNGRAKIIEFSI
What is the function of this protein?
Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).  To a lesser extent, can also use CTP, UTP, and GTP as the nucleotide triphosphate substrate.
What are the official names of this protein?
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin diphosphokinase, 6-HMPDK, 7,8-dihydro-6-hydroxymethylpterin diphosphokinase, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase, PPPK.
What is the protein family that this protein belongs to?
Belongs to the archaeal 6-HMPDK family.
Protein: CBPYA_SORMK
Sequence: MRISASTVLLGAASAASAASFQNQAQQVLADNFHKAHDAIKPVADSFAHTTLESFEEAFNGMNSQAKALWDEIKLLVPESAFDKPTWFSKPKAAKRRKDWDHVVKGADVQKLWVKGADGEKHREVGGQLDNFNLRVKSVDPSKLGVDKVKQYSGYLDDEANDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPSSIDKKLKVINNEYAWNNNASVIFLDQPVNVGYSYSGNAVSNTVAAGKDVYALLTLFFHQFPEYAKQDFHIAGESYAGHYIPVFASEILSHKDRNINLKSVLIGNGLTDPLTQYEHYRPMACGEGGYPAVLSESECRSMDNALPRCQSLIRNCYESGSVWSCVPAAIYCNNQFIGPYQRTGQNVYDIRGKCEDDNNLCYSALGWISDYLNQKDVMDALGVEVESYDSCNFDINRNFLFQGDWMQPFHRLVPGILKEIPVLIYAGDADFICNWLGNKAWSEALEWPGKKGFNKAELEDLSLPEADKEYGKVKSSGNFTFMQIYQAGHMVPMDQPENSLDFLNRWLGGEWFEQ
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: SARZ_STAS1
Sequence: MEEKDNTLERQLCFLFYVSSKEIIKKYTSYLKEFDLTYTGYIVLLAIGVEEKLNIKTLGARVFLDSGTLTPLLKKLEKKGYVTRTREIDDERNLQIALTTKGKDIKEPLSNISKQVFNEFDMEVDEAIDLKETLQNFVNKHFQQNI
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_AZOOP
Sequence: MLIRRPPDLLPSEITPEPLARGRRALLKGLGAGAALAGLGLPQISQAGSLGTLRPSPLSSDEKLTPLKSVTGYNNFYEFGTDKEDPARHAPGRLKTRPWTVTVEGEIKRPRTFSIDDLLKLAPLEERIYRMRCVEGWSMVIPWVGFPLAELIRQVEPNGQARFVEFVTLADPQQMPGVRSPLLDWPYVEGLRLDEAQHPLTLLAVGLYGEVLPAQNGAPIRLVVPWKYGFKSAKSIVRIRFVREQPRSTWMKAGPSEYGFYSNVNPAVDHPRWSQATERRIGEFIKRKTLPFNGYADQVAGLYSGMDLRRFF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide (By similarity).  Involved in protection against reactive chlorine species (RCS) generated by chlorite and hypochlorite (PubMed:25968643).
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: PTH_LACDB
Sequence: MKLIVALGNPGLKYEKTKHNTGFMALDHYLDEKGLRLDRDKFTALYAKEKVAGEDVIFMEPQTYMNESGRAVGAAAKFFKIDPSDILVIHDDMDMPIAKLRIRAGGKSGGHNGIKSIIACLGTEKFNRLKIGIRHPDKQSVVSWVLTPFNPDQQKELEASFAKVDQIIDDFIAGKDAQYLMNRYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A16_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELEAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.16, HNTX-II.16, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_CHLL2
Sequence: MNPLCSEFTSSSRKAPEAAIGQVLIEALPYIRKFEGKTFVIKYGGSAMKDELLKNSFAQNVTLLRKVGINVVLVHGGGDAITRTAEKLGLVSQFVHGKRVTDNDMITVVQMTLAGKVNQDIVRLLSEHGGKAVGVTGLDADTIKAVPGPNAEKLGLVGDVESINTDYIDLLCRAGLIPVIAPVGYDHNGNIYNINADDAASSIAIALKAEKLIYVSDVEGIQVGERILKTICKAEAADFIEQGIISGGMIPKVLSAFKTLDGGVRKIHLIDGKFTHSLLLEIFTHEGIGTQFIAEQDNDQQENR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_KOCRD
Sequence: MVYAIVRAGGRQEKVSVGDLVTLDRVAGEAGSTVELPALLLVDGDKVTSDSKTLADVKVTAEIIEDLRGPKISIMKYKNKTGYKKRQGFRAELTTVKITGIDA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: EX7S_RICPR
Sequence: MTNTKTLKDNISFEEALRELEEIVKKIDTGQENLETAVNSFERGILLKNHCEKKLKEARLKIEKITKLADSTVILEETEV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_SYNAS
Sequence: MFASVLKKIVGTKNDRELKKYSLIQREINALESSIAALSDEQLKEKTPYFKEKLHTGASLDDILPEAFAVVREVARRTVNMRPFDVQLIGGMVLHEGKIAEMKTGEGKTLVATMPMYLNALEGKGAHLVTVNDYLASRDAEWMSPIYSFLGLSVGVIVHGMDDDERRAAYACDITYGTNNEFGFDYLRDNMKYSLEDYTQREFNYSIVDEVDSILIDEARTPLIISGPSEESTDKYYRINQIIPRLKKERDYTIDEKSRTVVLTEEGVARVESYLNVSNLYEPRNIDTLHHVNQALKAHTLFKRDVDYLVKDGQVIIVDEFTGRIMPGRRYSDGLHQALEAKEKVKIEQENQTLASITFQNFFRMYSKLAGMTGTADTEAAEFKKIYNLDVVVVPTNMPMIRVDHTDVIYKTEKEKFSAVIEEIKELHKAKRPVLVGTISIEKSELLSKYLTQTGIQHHVLNAKNHEKEAEIVSQAGQPGQVTISTNMAGRGTDIKLGERVAELGGLHILGTERHESRRIDNQLRGRSGRQGDMGSSRFYLSLEDDLLRIFGAEKISSIMDKIGIEENQPIEHKLISRAIENAQKRVEGQNFDIRKHLLEYDDVMNRQRQVIYEQRRNVLKGDELREDLLDMIEEVVEDFVPEYVDEKRHPDEWNLKGLEDRVLKQFSLRLDFSKSGDVGSLEDIQEKIVAAVNDLLNRKEAEFGKPLMDYLIRMISIQSIDSHWKDHLLAMDHLKEGIGLRGYGQKDPVREYQKEGYDLFMDMIRRIKEDTLEKLCMVQIRREEEVEEMREQSRQNYIMNRGEDIAAPATVRRKNEKVGRNDPCPCGSGKKYKKCCGANK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CLE18_ARATH
Sequence: MHLLKGGVVLIITLILFLITSSIVAIREDPSLIGVDRQIPTGPDPLHNPPQPSPKHHHWIGVEENNIDRSWNYVDYESHHAHSPIHNSPEPAPLYRHLIGV
What is the function of this protein?
Extracellular signal peptide that regulates cell fate (PubMed:16489133).  Represses root apical meristem maintenance (PubMed:16902140).  Root growth factor that regulates the pattern of root growth and lateral root development (PubMed:22307643).  Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2 (PubMed:28607033).
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE18p]: Secreted, extracellular space. SUBCELLULAR LOCATION: [CLE18 C-terminus]: Secreted.
Protein: IL1AP_HUMAN
Sequence: MTLLWCVVSLYFYGILQSDASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKFNYSTAHSAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSPMKLPVHKLYIEYGIQRITCPNVDGYFPSSVKPTITWYMGCYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNAVPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDVTINESISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPRYTVELACGFGATVLLVVILIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYARNAEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKETKVKELKRAKTVLTVIKWKGEKSKYPQGRFWKQLQVAMPVKKSPRRSSSDEQGLSYSSLKNV
What is the function of this protein?
Unable to mediate canonical IL-1 signaling (PubMed:19481478).  Required for Src phosphorylation by IL1B.  May be involved in IL1B-potentiated NMDA-induced calcium influx in neurons (By similarity).
What are the official names of this protein?
Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP, Interleukin-1 receptor 3, IL-1R-3, IL-1R3.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: DBPA_ECOLI
Sequence: MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK
What is the function of this protein?
DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit.  Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.  Requires a single-stranded RNA loading site on the 3' side of the substrate helix.
What are the official names of this protein?
ATP-dependent RNA helicase DbpA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DbpA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR039_YEAST
Sequence: MSKHKHEWTESVANSGPASILSYCASSILMTVTNKFVVNLDNFNMNFVMLFVQSLVCTVTLCILRIVGVANF
What are the official names of this protein?
Uncharacterized protein YER039C-A.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y3201_BURP0
Sequence: MSADSADSVPSPRSAFATTLQIVSVVSFTFICYLTIGLPLAVLPGFVHDELGFSAIVAGAAISVQYFATLASRPLAGRCADTLGPKRTVLRGLAACGASGALLLSAFAFARWPAASIVLLVASRLVLGIGESLVGTGAILWGIGRVGTAHNARVISWNGIATYGALAIGAPVGVAISHALIPAVLGMLVIALAALGYYLARLITPVPLVHGERMSYASVLTRVLPHGLGLALGSAGFGSIATFITLYYAARHWPNAALSLTVFGTLFIGARLLFANTIKTHGGFRVAIVSFAFECAGLLMLWLAPVPHVALVGAALTGFGFALIFPALGVEAVALVPPASRGAALSAYSVFLDLSLGITGPLAGYVAGAFGYPQVFLCAAVAAAAGVALSTVLYQRQARLSGSGAAA
What are the official names of this protein?
Uncharacterized MFS-type transporter BURPS1106A_3201.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PA24A_HORSE
Sequence: MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRTRHFNNNINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTLSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYLAGLSGSSWYMSTLYSHPDFPEKGPEEINKELMKNVSYDPLLLLTPQKIKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDESQEPKGTENEDAERDYQNDNQASWVHRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLRNFTTQESLDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETKEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKNAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLNKPTA
What is the function of this protein?
Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response (By similarity).  Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production (By similarity).  Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity).  Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway.  In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position.  This hydrolysis is not stereospecific.  Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides.  Has O-acyltransferase activity.  Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis (By similarity).
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane. Nucleus envelope. Note=Translocates to intracellular membranes in a calcium-dependent way.
Protein: TATB_HELHP
Sequence: MFGVGIFEVLVILIVAVIALGPNKLPQTIVDIVKFFRAVKKTMAEAKETFDKEIQLSEIKQEALKYKDTLESEVNKLTKDIRLDELREISVDSLTKPLQETKEVLSEEAKNLQSTLESLNSDISYESSAAAQTPTTQESIPTDSTREIAYATQKPQNSIDSINSKESSVDSLHSPSIVESTQSSSSKDS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ZNT9_PONAB
Sequence: MLPGLAAAAAAHRCSWSSLCRLRPRCRAAACNPSDCQEWQNLVTFGSFSNMVPCSHPYIGTLSQVKLYSTDVQKEGQGSQTLRVEKVPSFETAEGIGAELKAPLKQEPLQVRVKAVLKKREYGSKYTQNNFITGVRAINEFCLKSSDLEQLRKIRRRSPHEDTESFTVYLRSDVEAKSLEVWGSPEALAREKKLRKEAEIEYRERLFRNQKILREYRDFLGNTKPRSRTASVFFKGPGKVVMVAICINGLNCFFKFLAWIYTGSASMFSEAIHSLSDTCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLISGVGIFMMGAGLSWYHGVMGLLHPQPIESLLWAYCILAGSLVSEGATLLVAVNELRRNARAKGMSFYKYVMESRDPSTNVILLEDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGVGTLLGMVSAFLIYTNTEALLGRSIQPEQVQRLTELLENDPSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEKQDFDQMLQEIQEVKTPEELETFMLKHGENIIDTLGAEVDRLEKELKKRNPEVRHVDLEIL
What is the function of this protein?
Mitochondrial proton-coupled zinc ion antiporter mediating the export of zinc from the mitochondria and involved in zinc homeostasis, zinc mobilization as well as mitochondrial morphology and health (By similarity).  In nucleus, functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes.  Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A9, mitochondrial, Solute carrier family 30 member 9, Zinc transporter 9, ZnT-9.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Nucleus. Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Note=Mainly in the cytoplasm. Partial co-localization with endoplasmic reticulum.
Protein: GRAS_STAAE
Sequence: MNNLKWVAYFLKSRMNWIFWILFLNFLMLGISLIDYDFPIDSLFYIVSLNLSLTMIFLLLTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQISAHKEKVVEQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEKNQERKQALLYEWSRINSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDDYVYTDIKWCRMIIRQILSNALKYSENFNIEIGTELNDQHVSLYIKDYGRGISKKDMPRIFERGFTSTANRNETTSSGMGLYLVNSVKDQLGIHLQVTSTVGKGTTVRLIFPLQNEIVERMSEVTNLSF
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Functions as a sensor protein kinase which phosphorylates GraR through the auxiliary protein GraX.  In turn, GraR up-regulates many genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Sensor protein kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUA_ACIBT
Sequence: MQRYAVGIEFSGIQYRGWQTQQPGVASVQETIERVLSKIADEPITLHGAGRTDAGVHATNMVAHFDTNAIRPERGWIMGANSQLPKDISIQWIKQMDEEFHARFKATARRYRYVVYNAPHRPALLHKQVTHIYQKLDVQKMIKAASKFEGTHNFETFRAAACQSNQPVRHVKHCRLFEHGRYLVLDIQADGFLHHMVRNIMGCLLEIGQGMYEIDHIDAMFAAEDRKAAGITAPPDGLYFIQCYYPEQFDLPHPPLGPHWLNLPE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL14_BACC7
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RNC_SHEB5
Sequence: MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGDTLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAIIGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTLLQEHLQGFKKPLPDYQVINIEGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_STAA2
Sequence: MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.