PharMolix/UniProtQA huggingface dataset:
Protein: EFG_EHRCJ
Sequence: MNIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNGHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGADFYRCVDMLVDRLGATPLVLQLPIGSEKDFVGVVDLLEMRSIIWDEDSLGASFHYGEIPKDMIDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSLLKSCIRTGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPVIEALDVKTSNTINVKTSAGGKFVALAFKVMTDKFVGSLTFIRIYSGKLSSKTTVLNAVKDSTESIGRILLMHANNREDITEAQAGDIVALAGLKKTVTGDTLCALDYPVILERMEFPEPVMEIAVEPKSTADQEKMGIALSRLVAEDPSLGMYVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQVAYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQSGLENIRGSGMLAGFPVIDFKATLFDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTKVILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNIVANEIKTK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTF4_HUMAN
Sequence: MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
What is the function of this protein?
Target-derived survival factor for peripheral sensory sympathetic neurons.
What are the official names of this protein?
Neurotrophin-4, NT-4, Neurotrophin-5, NT-5, Neutrophic factor 4.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CC038_MOUSE
Sequence: MSGLSHLESEGCRNLLGLLDNDEIMALCDTVTNRLVQPVDRQDAIHAILVYSQNVEELLRRKKVHREVIFKYLAKQGVVVPPTAEKHNLIQYAKDYWAKQSPKLKDTAEPVTKTEDIQLFKQQAKEDKEAEKVDFRRLGEEFCHWFFELLNSQNPFLGPPQDDWGPQHFWHDAKLRFYYNTSEQNTTDYQGAEIVSLRLLSLVKEEFLFLSPNLDSQGLKCASSPHGLVMVGVAGTVHRGNSCLGIFEQIFGLIRSPFVENTWKIKFINLRIIGGSSLAPESVLKPSVTFEPSDLEAFYNVITLCNSPEVRPNVRQIIDSGTGDQVLHSGDEALLNKREMNLLTPLKH
What is the function of this protein?
May be involved in apoptosis regulation.
What are the official names of this protein?
Uncharacterized protein C3orf38 homolog.
Protein: OXR1_CRYNJ
Sequence: MPHHHSLPTSSADFGDFNSAPASSIQTSSLSQDDLLGSYDETIRHSPSVKSHPSPDPRASNLDLLFLDHNAEEHRRPEPTYSPRSRPTGVLPESVPHARSPRRLSTFSSSTSPTSPPSITDAGCDIIFHPFYDHMDVNATRAMQKMQGHGERGASKRSDKMQLRGQASHSRIAPSSSPPHSRLLDTLATTTKLASKWRSVITHPTSPNTADQTHNGQPKPQIRHAETSPMDITHDTPFASAEQIAGSYIPPTGAPGFTQASVLGMKHHGDGPFEPLTLIGRKDSTSNVLTPEDAIGLKACLPPRQRLTNQWTLLFSLDQHGASLSTLYRLIDIYSVSHQSSGNILVIRDGHGNRFGTYMNEPIVKREGTYYGSGESFLFKLTHSCQTIPYRWTGKNKYFALCEAGFMSFGGGAGAYGLILDSTFTHNSSATCPAYNNDILCELEPLKSQHAQSFQCLGLEVWSTL
What is the function of this protein?
May be involved in protection from oxidative damage.
What are the official names of this protein?
Oxidation resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARGB_SALNS
Sequence: MNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FZD5_XENLA
Sequence: MGSFRSGVFALSFVVLLLDYFAPAQAASKAIVCQEITVPMCKGIGYNHTYMPNQFNHDTQDEAGMEVHQFWPLVVIQCSLDLKFFLCSMYTPICLPDYRKPLPPCRSVCERAKAGCSPLMRKYGFAWPERMNCDRLPEHGDPDTLCMYYNWTETTTTLPPTHPPKVKTPTSDCDGVCKCREPFVSITRESHPLYNRIKTGQVPNCAMPCFQPYFTQDEKMFVTFWIGLWSILCFISTFTTVATFLIDMERFRYPERPIIFLSACYLFVSIGYVVRLIVGHENVACNKDHIHYETTGPALCTIVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVVYLFSGTMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACYIYEQHYREHWEKTHNCSCPGDKQRYRPDYAVFMLKYLMCLVVGITSGVWIWSGKTLESWKRFTGRCCRNSKPINASAYSEASRALTPRTGLSNLTLPHKQVPLSHV
What is the function of this protein?
Receptor for Wnt proteins.  Functions in the canonical Wnt/beta-catenin signaling pathway.  The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
What are the official names of this protein?
Frizzled-5, Fz-5, Xfz5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and also found at the Golgi.
Protein: FUMOA_CORFA
Sequence: MVATLANLNFPYLILSACLSAILLSRFLPFTRRDRRPTAKGCLPEPRVFQWDVFFGLDIPISQGRALQQNRYLEWLRDLHASMPRTKTFSVNFGGYRWIYSIEPEILKAVYATNFQDFGVEPIRQHPPGFKPFAEKGVSTSDGEDWAFSRSLIKPFFERSVYVSTDRVKPFADKFLTFIPEDGETFDIQPLLQRWFLDMTSEFIFGKSQDSMTHPERAEVIWAMADVLRGTRLRAQTYKILWAFNWDWWFKAIEKVHGFLNPYIRSTLAELAERQQRVKEGLPVGEERTDLLWSMATMLPEEEALRSQVCIIFVPNNDTTSIFIAHCLYFLARHPDAWRKLREEVTAVGDAPITFELLRNMKYLNGIMNETHRLIPNNVTQIRSALSDVVLPLGGGPDGKAPLDVRKGDIVSVTKTVMYRDPDRWGADADEYRPERWDGMRGGWHFLPYGGGPRRCPAQMMVQNESGYMLCRLARRYARIEARDKEPYRARMRIGPSSLHGVKIAFYKE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fumosorinone, a 2-pyridone alkaloid that acts as an inhibitor of protein tyrosine phosphatase 1B which is implicated asa negative regulator of insulin receptor signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes (PubMed:25857260).  The polyketide-amino acid backbone of fumosorinone is first assembled by the PKS-NRPS hybrid fumoS (PubMed:25857260).  The PKS modules condense one acetyl-CoA starter unit with 7 malonyl-CoA units, programmed C-methylations occurring after the first 3 and the sixth extensions, and cycles of full reduction occurring after the first 2 extensions (Probable).  Because fumoS lacks a designated enoyl reductase (ER) domain, the required activity is provided the enoyl reductase fumoC (Probable).  Upon formation of the polyketide backbone on the thiotemplate, the polyketide is transferred to the NRPS module and linked to tyrosine to produce the acyltetramic acid intermediate called prefumosorinone A (Probable).  The cytochrome P450 monooxygenase fumoA then probably catalyzes an unprecedented oxidative ring expansion of prefumosorinone A to form prefumosorinone B which contains the 2-pyridone core of fumosorinone (Probable).  The cytochrome P450 monooxygenase fumoB might hydroxylate the nitrogen of prefumosorinone B, but not the acyltetramic acid prefumosorinone A, to form fumosorinone (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase fumoA, Fumosorinone biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLMU_STAAN
Sequence: MRRHAIILAAGKGTRMKSKKYKVLHEVAGKPMVEHVLESVKGSGVDQVVTIVGHGAESVKGHLGERSLYSFQEKQLGTAHAVQMAKSHLEDKEGTTIVVCGDTPLITKETLETLIAHHEDANAQATVLSASIQQPYGYGRIVRNASGRLERIVEEKDATQAEKDINEISSGIFAFNNKTLFEKLTQVKNDNAQGEYYLPDVLSLILNDGGIVEVYRTNDVEEIMGVNDRVMLSQAEKAMQRRTNHYHMLNGVTIIDPDSTFIGPDVTIGSDTVIEPGVRINGRTEIGEDVVIGQYSEINNSTIENGACIQQSVVNDASVGANTKVGPFAQLRPGAQLGADVKVGNFVEIKKADLKDGAKVSHLSYIGDAVIGERTNIGCGTITVNYDGENKFKTIVGKDSFVGCNVNLVAPVTIGDDVLVAAGSTITDDVPNDSLAVARARQTTKEGYRK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMAL4_MOUSE
Sequence: MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSMPSKGQPSLREAISMSCITNGSGISRKQNHTSSVSIARKETLSSAAKSGTEKKKEKPQGQREKKEDSHSNDQSPQIRASPSPQPSSQPLQINRQTPESKSSAPIKSIKRPPTAEKSHNSWENSDDSRNKLMKTVSTSKLISKVIKNADKHKDVIVNQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWVYGYRGKDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVRCLAVHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVSLTTLHVIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKKSKIAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTMVEPPPGKGPKGVYQINRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNLEREIEVPDQYGTIRAVAEGRAEQFLVGTSRNFILRGTFNDGFQIEVQGHRDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLPVPQNEVITDASVTKTPASSSETARPSNSPPLPPSLPLTGTAEEESRMGSSPTLVENSLEQIAEPSEEQSEWGSEDLGVVIDEEPASELSETQGATELPEEERGITPLC
What is the function of this protein?
Essential for the stability of microtubules (MTs) (PubMed:17196341).  Essential for the formation of MTs (By similarity).  Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (By similarity).  Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (By similarity).
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 4, EMAP-4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center. Midbody. Note=Localizes to microtubules (MTs) during interphase with a significantly reduced affinity for MTs during mitosis.
Protein: SUCC_ALISL
Sequence: MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKNLVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRRIVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQGRELAFKLGLEGDQIKQFVKIFLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDEREAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YG1D_YEAST
Sequence: MLVRNRYLGELLKNSRSFSVLNSSVRSGHNKWSTIKHGKAKNDAERNKINNKFANQIAMSVKLGNGITDPSMNIRLATSIELANKNNVSKKVIENAIRKASGSSASGKDSNASELCVYEGMGPGGVAIVVEALTDNKNRTIGLIRSAFNKANGSMTPTLFFFDKKGYVTMVPPKMLDTEDKVLESVLEIQGIEDIAPVQEDAEDLECDTETETTGQTYEAVMEPADTNKVAALLKERGFHIRDLGIGYNAKPDMEVFVQGDETLEKLQKLTTALEDIDEVTSLYTNASNA
What are the official names of this protein?
Probable transcriptional regulatory protein HAH1.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYAA_SHIFL
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPRMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNLPPANQDHDTPLLQQYFS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_LACP7
Sequence: MAKVNFDYSIAKQFFSKEELSYMKGAAEAAKQILLEKTGAGNDFLGWIDLPVDYDKEEFERIITSAKKIQSDSEVLLVIGIGGSYLGARAAIEFLRHSFYNSVSKEVRKTPEIYYVGNNISSTYLSHLIEVIGDRDFSVNIISKSGTTTEPAIAFRIFKKLLIQKYGKVEAAKRIYATTDKSKGALKNLATEEGYESFVVPDDVGGRFSVLTAVGLLPIAVSGADIKQLMDGAASMRERCLNNKFEENDSLLYASIRNILLRKGKNIEILANYEPALHYVGEWWKQLYGESEGKDKKGIFPASVDLTTDLHSMGQFIQDGQRTMFETVINLEKSTCEVILEEEDVDLDGLNYLAGKSVDFINKSAMKGTLLAHTDGDVPNLIVNIAEQSEFCLGELFYFFEFACGVSGYILGVNPFDQPGVESYKKNMFALLGKPGFEELSKKLQERLQ
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM2_STAA3
Sequence: MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVEGTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDIKAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLFDVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: ARASP_ARATH
Sequence: MLLNISSSPISHRNPHFLSNFNNPISYFPRRSKTHLSKSHFFPKFTPLSNQSLKNRVLFGNKRYPDGERFDFRSRAISGIDLGSFESVLEAIAVLTTIIVVHESGHFLAASLQGIHVSKFAIGFGPILAKFDYNNVEYSLRAFPLGGFVGFPDNDPDSEIPIDDENLLKNRPTLDRSIVVSAGIIANVIFAYAIIFVQVLSVGLPVQEAFPGVLVPEVKTFSAASRDGLLSGDVILAVDGTELSKTGPDAVSKIVDIVKRNPKSNVVFRIERGGEDFDIRVTPDKNFDGTGKIGVQLSPNVRITKVRPRNIPETFRFVGREFMGLSSNVLDGLKQTFFNFSQTASKVAGPVAIIAVGAEVARSNIDGLYQFAALLNINLAVINLLPLPALDGGTLALILLEAVRGGKKLPVEVEQGIMSSGIMLVIFLGLFLIVKDTLSLDFIKEML
What is the function of this protein?
Metalloprotease essential for chloroplast and plant development.  May be involved in regulated intramembrane proteolysis (RIP).
What are the official names of this protein?
Membrane metalloprotease ARASP, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50A family.
Protein: XG74_HYPJQ
Sequence: MKVSRVLALVLGAVIPAHAAFSWKNVKLGGGGGFVPGIIFHPKTKGVAYARTDIGGLYRLNADDSWTAVTDGIADNAGWHNWGIDAVALDPQDDQKVYAAVGMYTNSWDPSNGAIIRSSDRGATWSFTNLPFKVGGNMPGRGAGERLAVDPANSNIIYFGARSGNGLWKSTDGGVTFSKVSSFTATGTYIPDPSDSNGYNSDKQGLMWVTFDSTSSTTGGATSRIFVGTADNITASVYVSTNAGSTWSAVPGQPGKYFPHKAKLQPAEKALYLTYSDGTGPYDGTLGSVWRYDIAGGTWKDITPVSGSDLYFGFGGLGLDLQKPGTLVVASLNSWWPDAQLFRSTDSGTTWSPIWAWASYPTETYYYSISTPKAPWIKNNFIDVTSESPSDGLIKRLGWMIESLEIDPTDSNHWLYGTGMTIFGGHDLTNWDTRHNVSIQSLADGIEEFSVQDLASAPGGSELLAAVGDDNGFTFASRNDLGTSPQTVWATPTWATSTSVDYAGNSVKSVVRVGNTAGTQQVAISSDGGATWSIDYAADTSMNGGTVAYSADGDTILWSTASSGVQRSQFQGSFASVSSLPAGAVIASDKKTNSVFYAGSGSTFYVSKDTGSSFTRGPKLGSAGTIRDIAAHPTTAGTLYVSTDVGIFRSTDSGTTFGQVSTALTNTYQIALGVGSGSNWNLYAFGTGPSGARLYASGDSGASWTDIQGSQGFGSIDSTKVAGSGSTAGQVYVGTNGRGVFYAQGTVGGGTGGTSSSTKQSSSSTSSASSSTTLRSSVVSTTRASTVTSSRTSSAAGPTGSGVAGHYAQCGGIGWTGPTQCVAPYVCQKQNDYYYQCV
What is the function of this protein?
Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG.  Has a low activity against beta-glucan and carboxymethylcellulose.  Not active against Avicel, laminarin, xylan, galactomannan, linear and branched arabinans, galactan, polygalacturonic acid, starch, beta-D-Glcp, beta-D-cellobiose, beta-D-Galp, beta-D-Xylp, alpha-D-Xylp, alpha-L-Araf and alpha-L-Arap.
What are the official names of this protein?
Xyloglucanase, XG, Cel74a.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 74 family.
Protein: RBSD_CUTAK
Sequence: MKKSGLLNPQLCAAVARLGHTQTFVVADAGLPIPHEVPVIDLAVVLGTPRFQEVFDAILDEVVVDGATIAHEALGHEPESWVRERIEEVHTVSHEDLKKALPNVSFVVRTGETTPYSNVIVRCGVPF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_BURTA
Sequence: MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECAARVAQAGFSIRNVDSTIIAQAPKLAPHIDAMRANIAADLGLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: EXP23_ARATH
Sequence: MNLLGKMIYVEGFMMIMATLLVSMSYGHRAMINDVAEAPVFDDVVSPNGLDSSWYDARATFYGDIHGGETQQGACGYGDLFKQGYGLETAALSTALFNEGYTCGACYQIMCVNDPQWCLPGSVKITATNFCPPDYSKTEGVWCNPPQKHFDLSLPMFLKIAQYKAGVVPVKYRRISCARTGGVKFETKGNPYFLMILPYNVGGAGDIKLMQVKGDKTGWITMQKNWGQNWTTGVNLTGQGISFRVTTSDGVTKDFNNVMPNNWGFGQTFDGKINF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A23, AtEXPA23, Alpha-expansin-23, At-EXP23, AtEx23, Ath-ExpAlpha-1.17.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RL29_CUPMC
Sequence: MKASELRGKDAAGLNQELSELLKAQFSLRMQKATQQLQNTSQLKKVRKDIARVQTVLTEKANAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYI_NEIG2
Sequence: MTDYSKTVNLLESPFPMRGNLAKCEPAWLKSWYEQKRYQKLREIAKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQAGFDAPYVPGWDCHGLPIEVMVEKLHGKDMPKARFRELCREYAAEQIARQKKDFIRLGVLGDWDNPYLTMDFKTEADTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEVEYKDKVSPAIDVAYPFKDTVALAAAFGLAGIEGKAFAVIWTTTPWTLPASQAVSAGADVVYQLIDTPKGKLVLAKDLAEGALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDIPMLNGEHVTTDAGTGLVHTAPAHGLEDYAVCNKYGIELYNPVNAEGKYISETPRVAGMSVWEANPVILQWPEETGNLLASSKIEHSYAHCWRHKTPLIYRATGQWFVGMDKAGSDGKTLRDKAIKAVDDTEFFPPWGRARLESMIEGRPDWVVSRQRYWGTPMTFFVHKETGELHPNSAELLEKVAQRIEEKGIEAWFSLDKSELLSAEDCEHYDKLPDTMDVWFDSGSTHYSVVKQREELEWPADLYLEGSDQHRGWFQSSMLTGCASSMGRAPYKQLLTHGFVVDQNGRKMSKSIGNVVAPQEVYNEFGADILRLWAASTDYSGELAISKEILKRVTESYRRIRNTLSFLFANLSDFNPIEDAVPQAEMVEIDRYALVLARRLQERLAGGYYPRYAFHFAVKDIVSFCSEDLGAFYLDILKDRLYTTKADSRARRSAQTALYHITRSLVLLIAPILCFTGEEAWDIIGGGEEDSVLFHTWHEFPAINEKAEAELVKKWTAIREAREAVTAAIEPLRADKTVGSSLQAEAEITAPEEMAGYLNALGEELRFALLVSKAEVKVGDELAVAAKASDGEKCERCWHYTRDVGAVAGYETVCKRCAENVGGEGETRHYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REEP4_XENTR
Sequence: MVSWIISRAVVLVFGLLYPAYASYKAVKTKNVREYVRWMMYWIVFALFMTVETFTDIFIAWFPFYYEIKMAFVVWLLSPYTRGASLLYRKCIHPTLSLKEKEIDSYIIQAKERSYESFVNIGRKGLNIAASAAVQAATKGQGALVGRLRSFSMQDLRALPDDTPIHYRDALYPDAPELHRRPIGYPTTSHADSDSMDERWSDSEMAETRTAARTRGGMPSKPLQRSQSLRVSKKKGLSREVSTKTTKPKGKKKPAQSEPEN
What is the function of this protein?
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis.  Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity).  May play a role in the maintenance of both the nervous system and the musculature.
What are the official names of this protein?
Receptor expression-enhancing protein 4.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SSI_STRNE
Sequence: SLFAPSALVLTVGEGESAADSGVQRAVTLTCTPKASGTHPAARAACDQLRAVDGDFKALVTTKSDRVCTKEYRPIVITAEGVWDGHRVSYEHKFANPCMASDGKGVVFEF
What are the official names of this protein?
Protease inhibitor SIL-V1/SIL-V4.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3MGH_FRACC
Sequence: MAPTDGAAPDGVDFYDRPVLAVAPALLGATVWHGPVAVRITEVEAYGGLDDPASHAYRGPTPRAAVMFGPPGRAYVYLSYGVHWCLNVVCGPVGSASAVLLRSGEVVAGRDLVAGRFPRLVEADLARGPGRLGRALAVTGALSGTTITGPGPVTVALAGGRGIRPPGPPGISGGRVRRGPRAGIRVATEWPWRFWLAGEATVSGPRPPRRPR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.