PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_PSEP1
Sequence: MSGKPPAIFLMGPTAAGKTDLAIELTTVLPCELISVDSALVYRGMDIGSAKPSKEVLAAHPHRLIDIRDPAQSYSAAQFRTDALEAMAEITARGKIPLLVGGTMLYYKALIDGLADMPAADATVRAELEAQAEALGLAELHRQLAEVDPESAARIHPNDPQRLIRALEVYRVSGESMTAHRRRQFAESRGADAGAGGHLPYTVASLAIAPTDRHILHQRIALRFSQMLEQGFVDEVRSLRARSDLHAGLPSIRAVGYRQVWDYLDGKLTENEMRERGIIATRQLAKRQFTWLRGWPDVHWLDSLACDNLSRTLKYLGAISILS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SLU7_CRYNJ
Sequence: MLSTSTSLQGGKVSREEYRRQKDLEAARKAGTAPAALDEQGNAINPHIPEYITKAPWYADTGRPSLAHQRINEQGPHLKLDEWYDRGAKAGPAAKKYRKGACENCGAMTHKMKDCVERPRKRGAKFTNKDIAPDELVQQFEGDYDAKRDRWNGYDPASYKHVVEEYEATEQMRKKYREEEIDQQTSTDMAVVKKLAKKDKEGKVEDDDDDFGSSDEDEDDEDKYADAADQVGQKLDTKTRITVRNLRIREDTAKYLINLDESSAYYDPKTRSMRDAPVRNMNPEDMKFAGDNFQRYSGDATNMQKLQLFAWQSAQKGSNINVSANPTAGELLHREFQQKKEVLKDTNKTSILAKYGGEEHLQRMPNELLSGQTENYVEYSRSGQIIKGRERAKARSKYDEDVYINNHTAIWGSYYDLSTSQWGFACCHSVLPGSYCTGDAGKLANAASSASALLASSNERSKIEEAAEKERESLAEQHLKDLASGKAKKGKEREWDLPQYAKRREDGEELDLDKGRLKNALKEEKKRKKMGEDEAWQQTKKGKTDVTQEELEAYRLSRQAYDDPMSNYQDPEDQ
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHJG_ECOLI
Sequence: MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSAELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRVEATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWSFRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFGLKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGGVDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGDSDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKSVQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQPLKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAELRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNCAAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSPLYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILSQMKK
What are the official names of this protein?
AsmA family protein YhjG.
What is the protein family that this protein belongs to?
Belongs to the AsmA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COXX_STAAB
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KATL1_DANRE
Sequence: MNLTEICDNAKKGREYALLGNYDSSMVYYQGVIQQIHKHCQSLRDPAQKVKWQQVRQELAEEYEQVKSIVSTLESFKVDKAVDFPNPVPEEGPRDPDVWPPPTPAEHRGPVQVKKPVPLSKPQRKESPGMQHRGAVGRGQANIKPDRPNTRDGRGNKAKEEKSKRNAQEGAADVEQKKFDGTGYDSDLVDALERDIVSRNPNIHWDDIADLEDAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICGRRGTSDEHEASRRVKSELLVQMDGVGGAQESEDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKINLREVDVASDVDLTVFAEKIEGYSGADITNVCRDASMMAMRRRIQGLSPEEIRALSKDELQMPVTMEDFELALKKISKSVSAADLEKYESWMSEFGSV
What is the function of this protein?
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility.  Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A-like 1, Katanin p60 subunit A-like 1, p60 katanin-like 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (By similarity).
Protein: LUXS_SHEDO
Sequence: MPLLDSFTVDHTRMQAPAVRVAKQMNTPKGDAITVFDLRFCVPNKAILSERGIHTLEHLFAGFMRNHLNSESVEVIDISPMGCRTGFYMSLIGTPKEQEVANAWLHAMEDVLQVTKQEDIPELNEFQCGTFEMHSLPQAKAIAQDIISAGIGVNQNAELTLDESLLSKG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TRUA_SHIDS
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LOLA_HAEIN
Sequence: MKKTTLKFAALTLLGLSNLALADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQIISDGKTLWFYDPFVQQVTAQWVKNAVNNTPFVLLTSNDKSHWHQYTVTQQSDTFVLKPTLSTSNIKQFDIRVDANGILRNFSTTEKDGQTNLYVLRNITNQTLSDSLFQFKPEKGVEVDDQRKK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NDHK_SYNP2
Sequence: MVMNPTSFEQQQTEKLLNPMGRSQVTQDLSENVILTTVDDLYNWARLSSLWPLLYGTACCFIEFAALLGSRFDFDRFGLVPRSSPRQADLILVAGTVTMKMAPALVRLYEEMPEPKYVIAMGACTITGGMFSSDSTTAVRGVDKLIPVDLYIPGCPPRPEAIIDAIIKLRKKVSNETIQERSLKTEQTHRYYSTAHSMKVVEPILTGKYLGMDTWNNPPKELTEAMGMPVPPALLTAKQREEA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TS2_MAIZE
Sequence: MHASLASYAAAAMPALDLRPEIAHAHQPVMSPSHHGWDGNGATAVPTPMPKRLDGKVAIVTGGARGIGEAIVRLFAKHGARVVIADIDDAAGEALASALGPQVSFVRCDVSVEDDVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAARSILSFDAAEFDRVLRVNALGAALGMKHAARAMAPRRAGSIVSVASVAAVLGGLGPHAYTASKHAIVGLTKNAACELRAHGVRVNCVSPFGVATPMLINAWRQGHDDATADADRDLDLDLDVTVPSDQEVEKMEEVVRGLATLKGPTLRPRDIAEAVLFLASDEARYISGHNLVVDGGVTTSRNLIGL
What is the function of this protein?
Required for stage-specific floral organ abortion.
What are the official names of this protein?
Sex determination protein tasselseed-2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYH_BUCAI
Sequence: MNKEIKSIRGMYDYFPKDLKIWNYIEIIFKEVLNSYCYLEIRLPILEKTEIFKRAIGNVTDVVEKEMYSFNDRKGNNLTLRPEGTVGCVRAIIQNNLLQKSNKFWYLGPMFRYERPQKGRYRQFYQLGAEVFGLDTEDIDLEIIILTNRLWKRIGIDSFITLEVNSIGSKIDRVQYKKELVNFLKKREYLLDEDCKRRLYTNPLRILDSKNQDIQNLLKEAPLLSEYISFSENNHFKNLCNMMNHHGIKYKCNPHLVRGLDYYNSTVFEWKSNKLGAQNTICAGGRYDSLVQEMGGRKTPAIGFAIGIERLVLLVKSLKIFSEVIEESNVYIIFIGDNNKCHAINLSEEIRDLYPKLRIFINFLHQNLTKKIKNAISSLARIIILIGDNEIKKGFFLVKDLKEKKEYHLLKKELILKIQEIFK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STRPQ
Sequence: MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQSEELKAGRNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVADIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTGARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGETVISPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_IPOQU
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1480_ARCFU
Sequence: MIVLDTSIIIDYFRGVETTYNLIDEESEIAVTTINCSQIIRGDTFQLQAPLSC
What are the official names of this protein?
Uncharacterized protein AF_1480.
Protein: FRI1_PEA
Sequence: MALSSSKFSSFSGFSLSPVSGNGVQKPCFCDLRVGEKWGSRKFRVSATTAPLTGVIFEPFEEVKKDYLAVPSVPLVSLARQNFADECESVINEQINVEYNASYVYHSLFAYFDRDNVALKGFAKFFKESSEEHREHAEKLMKYQNTRGGRVVLHPIKDVPSEFEHVEKGDALYAMELALSLEKLTNEKLLNVHSVAERNNDLEMTHFIEGEYLAEQVEAIKKISEYVAQLRRVGKGHGVWHFDQRLLHGVHGA
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
What are the official names of this protein?
Ferritin-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid.
Protein: IF1_BACC1
Sequence: MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_BUCAP
Sequence: MKVLGIETSCDDTGIAIYDVSKGLLINELHSQKKIHANYGGIIPELASREHTRKIIFLLDKIFKEKNIMKEIDLIAYTAGPGLAGSLLVGATFACSLGFSLNIPVLPVNHMEAHLLSPMLEYKSMQFPFIALLVSGKHTQIIAAYELGKYEILGNSLDDAAGEAFDKVSKMLGLKYPSGRELSSLAAQGIKNYFYFPRPMIHHSSLNFSFSGLKTFTSKVISNNTLNIQQKANIARAFEDAVIDVLLIKTKKALYKKGWKRLVIAGGVSANTVLRKRSKDMMENVFHGKVFYSSLKFCTDNGAMIAYLGSLRYKEASVSQLEIIVKPKWSIDKLSYI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_RHOP5
Sequence: MSRRCELTAKGAQVGHKVSHSNIKTKRRFLPNLVNITFISDALGRQVRLRVSTNALKSVDHRGGLDGFLLKAKDAELSPKAVDIKRQIEKKKLTAELAAQA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HEMJ_CERS4
Sequence: MRMADHFEETTMGTFLADYYLWTKSLHVISVLAWMAGLFYLPRLFVYHAEVVKAGTETDALFQTMERRLLRAIMNPAMIATWIFGLLLVFTPGIVDWSMLWPWTKAACVLAMTGFHMWLAARRRDFAAGANRHKGRTYRMMNELPTLLMLVIVFSAVAKWNYWGF
What is the function of this protein?
Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.  Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll.  Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone.
What are the official names of this protein?
Protoporphyrinogen IX oxidase, PPO, ORF1.
What is the protein family that this protein belongs to?
Belongs to the HemJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_HAES1
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIANVLAEEGYIANVKVSEGVKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKNELPKVMGGLGVAVVSTSKGIMTDRKARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS10_RAT
Sequence: MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ
What is the function of this protein?
Component of the 40S ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Localized in the granular component (GC) region of the nucleolus. Methylation is required for its localization in the GC region. Colocalizes with NPS1 in the GC region of the nucleolus (By similarity).
Protein: ACSF_CYACA
Sequence: MVLNANHLQTKKTIKETLLAPRFYTTDFDEISRYDISSNFEEIEAIVNEFRSDYNKKHFIRDEEFDRHWSQIDAQTKQMFVEFLERSCTAEFSGFLLYKELARKLKEKMPVLAEGFLLMSRDEARHAGFLNKAMADFNLTLDLGFMTKNRRYTFFKPKFIFYATYLSEKIGYWRYITIYRHLEKHPEHRIYPIFKFFESWCQDENRHGDFFAAIVKSQPYLLEGFISKLWCRFFLLAVFATMYLNDCQRGEFYKSIGLDPRQFDIYVIQKTNESAAKLFPTVLDLDNPRFFECLDKCACYNKLLLEIDDREQPFFNQVLNVFYKFYLYFLLVLNFIMLYFLRTVNCNSFTRMVK
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SHE2_ZYGRC
Sequence: MRSRRTLQNKVYNELDSTRFRNQLIPESSRSTMLELTPEVLSILKEHTEVFSKYLSCYIHALNKFIGFLRKASSLRFERTVLIKYVKKLRFINDSLIAYNFEAEFPDPNNTHLDEAVKPLASFLLKSIELLDLLNYFLTQPLQKEIISKTLNSDLNLSGECIVAIEDTYNHFVKFAQWMIESLQIENTFFQIEVVQFTRKCAIEDGVDLENTDNIFLQQVVPVTDTEEYEVIAEEWAHILADKTLQLETKFNENVINWQNKFDKKKEDK
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner. The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA.
Protein: Y773_ARCFU
Sequence: MIEFAYSLKNDPKKAFDEIRSKAENLDFRPNLAIVYLTEHLQKDAKVFKFDFDTLWCLLKGL
What are the official names of this protein?
Uncharacterized protein AF_0773.
Protein: TGT_FRATW
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPINSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSPLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RIMP_FINM2
Sequence: MNKKYLRDLMNNDLSPLIKDTGIEFYDVEYSNNNGKNILTFYIEKDDGLISIDDCELINNKISDKLDEIDPISDPYYLEIASVDITTPFTRDKDFKKNLGNVVIVNLYQKLDSKKEFKGILTDFNDTEISLELEKKEIKIERSNISSIKLSLFD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T10IP_HUMAN
Sequence: MGQDTDMLNTYQQLVRTPSVRPGQDVRLQAPGTRTGLLKLLSTVSQDKQGCLGSGDGVPNQDLQQRSQSSRQTAKKDRKPRGQSKKGQGSEESEDHFPLLPRKPSFPFQWAWESIATDVRAVLQPSSPTPGHQALPMPSSFSQRQSRRKSTANLPEAHGCCWKTEAQNLKARQQLGAWGGVSIPTGKGELGSEPPSGLQLPGRRPGSGSASDKQVQLQSLGAEEAERGLSSGVLPQRPRRGSISEEEQFSEATEEAEEGEHRTPCRRRAGCQRKGQISGEEASDEGEVQGQSQGSSPSFNNLRRRQWRKTRAKELQGPWDLEKLHRQLQRDLDCGPQKLPWKTLRAAFQASKRNGKAYASGYDETFVSANLPNRTFHKRQEATRSLLQAWERQRQEERQQAELRRARTQHVQRQVAHCLAAYAPRGSRGPGAAQRKLEELRRQERQRFAEYQAELQGIQHRVQARPFLFQQAMQANARLTVTRRFSQVLSALGLDEEQLLSEAGKVDREGTPRKPRSHRSMGVRMEHSPQRPPRTEPTGSQPDRHYNPSLDPECSP
What are the official names of this protein?
Testis-specific protein 10-interacting protein, Tsga10-interacting protein.
Protein: NKX61_MOUSE
Sequence: MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGSHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSSGGSLLLHASEAEGSS
What is the function of this protein?
Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes.  Required for the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (PubMed:11076772).  Involved in transcriptional regulation of the insulin gene.  Together with NKX2-2 and IRX3, restricts the generation of motor neurons to the appropriate region of the neural tube.  Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.
What are the official names of this protein?
Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A.
What are the subcellular locations of this protein?
Nucleus.