PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_LISMO
Sequence: MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCNEIIEEELGISEFVDFGEVPKPQEIRHILSDYVIGQERAKKALAVAVYNHYKRINSNETKEDEVELSKSNICLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQELIQIDTGNILFIVGGAFDGIEQIVKNRMGEKVIGFGTDNAKLKDDETYLSRVVPEDLLKFGLIPEFIGRLPVIATLEQLDEAALVSILTEPKNALVKQYKRMLELDDVELEFEPTALIEIAKEAIERKTGARGLRSIIEQIMLEVMFEIPSRDDITKCIITEKAARGEEEPQLQLEDGSIIPIKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CCS_PIG
Sequence: MASDSRDRETACMLEFAVQMTCQSCVDAVSRSLQGVAGIQSVEVQLENQMVLVQTTLPSQVVQALLEDTGRQAVLKGMGSGRWQNLEAAVAILGGSGPVQGVVRFLQLTPERCLIEGTIDGLKPGLHGLHVHQFGDLTRNCNSCGDHFNPDGMSHGGPQDSDRHRGDLGNVCADADGRAVFRMEDELLKVWDVIGRSLVIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERXRPIAGEGRKEPAQPPAHL
What is the function of this protein?
Delivers copper to copper zinc superoxide dismutase (SOD1).
What are the official names of this protein?
Copper chaperone for superoxide dismutase, Superoxide dismutase copper chaperone.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_VEREI
Sequence: MAKVALIQRELKREKLVAKYAKKYVQLKAIAGDAKRSDAEREAARLGLQKLPRNANPTRQRNRCAITGRPRGTFRQFGLARAKIREMAFAGDIPGITKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y0630_DICDI
Sequence: MDINNIINNNKNNNDINYFEFPNNFIFVNNNTPPSSPSFSSETSSPPLSPLLPTSCRNDTYNNLVSNSNEGKFVFHNLFINEDNKHLFHKYFTSRKNLYKKYD
What are the official names of this protein?
Putative uncharacterized protein DDB_G0279811.
Protein: SYL_CYTH3
Sequence: MADYHFGEVENKWQSKWNAEKTFKALENSSKPKYFVLDMFPYPSGSGLHVGHPLGYIASDIMARYKRIKGYNVLHPMGFDSFGLPAEQYAVQTGQHPAITTEQNIARYIEQLNKIGFSFDWDREIRTSDPAYYKWTQWIFIQLFNHWYNKASDKAEPITNLVKQFETAGNAGINAACDEDAVTFTAADWKSYSEKQQSDTLLKYRLTYLSETMVNWCPGLGTVLANEEVKDGLSERGGFPVERKKMKQWSMRITAYADRLLKGLDTIDWPEAMKEMQRYWIGKSLGAMLTFKVVDKDMELTVFTTRIDTTFGVTYVSIAPEHEWIGALTSPEQKAAVEEYVTKAKNRSERDRMSDVKTVSGCFTGSYVTNPFNNEKIPVWIADYVLAGYGTGVVMAVPSSDERDYKFASFYKLPIISVQEGAHTDITKEDFDPKAGTMINSGFLNGLTVKQAIPEAIKFIEEKKIGFAKINFKMRDSIFGRQRYWGEPIPVSYKNDIPYVLNESELPLALPAIDEYKPTETGEPPLARNKAFADKGYELSTMPGWAGSSWYFMRYMDPQNKTAVAAADKINYWGQVDLYMGGAEHATGHLLYSRFWNKFLFDMGITPNDEPFAKLINQGMIQGVSKFAYRINGTNKFVSAGLKKEYDTTPIHVDVSIVHNDVLDTEAFKKWRPDFASAEFILENNTYVCGSEVEKMSKSKFNVVNPDDIVNKYGADTLRMYEMFLGPLEQSKPWNTNGIEGVYKFLNRFWRLFHDTAGNFAVSDAQPTAEELKVLHKTLKRVEEDIERFSFNTPVSTFMICVNELGSLKCNKRTILEPLTIALSPLAPHIAEELWSLLGHTTSVSTATYPAWDEKFLVESNHEYPISINGKMRAKLNLPVDMPAAEVEQQVLANEVVQKWLEGKAPKKIIVIPNKIVNVVM
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_LIMF3
Sequence: MKNGTIQQSLSGFYDIWSGGKLYRTRARGNFRKRGLKPVVGDQVEFEAENQREGYLLKILPRKNQLVRPMVANVDLAVVVTAVKEPNLSTNLLDRQLVALESQGIDPVIYFSKTDLLSDQEADALMLVVKGYQMIGYPVLYQRPPFGEEALGELRKILTGKVVTMMGQTGAGKSTLLNHLAPDLNLATGEISQALKRGRHTTRKVSLMQVGDALIADTPGFSSYEDFQMTVEELPHFFPEMQALAPECKFRGCLHIKEPSCAVKNALKHGKIMNSRYDNYLQFHELIANQKPNYQK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPD_BACAN
Sequence: MQTGKVKWFNSEKGFGFIEVEGGDDVFVHFSAIQGDGFKTLEEGQEVSFEIVEGNRGPQAANVTKN
What are the official names of this protein?
Cold shock-like protein CspD.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHI3_METAN
Sequence: QAAPDEGRASGHKLTVYWGAEDDTTTLDDVCNDSSYDVVNLAFLSHFFSAGGYPKMSIGNLDGPSQAQKKAGATGLQDGSSLVKSIKNCQSKGKPVILSMGGATDYSDVQLNSDAQGQQIANTVWNLFLGGTDHKELRPFGDVKLDGVDLDNETNDGTGYLAMTKQFKANFQKDTSKKYYITAAPQCPYPDQSEPLDVCQLLDWVQVQFYNNGNCNIAQRGFAKAVKNWSKGIGSGVQLYIGALASGADGDEGYVHAATLNRAVNQVKAMNLPNFGGAMLWEAHSAVKNGQLPEED
What is the function of this protein?
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Participates in the infection process and directly acts in the penetration process of the host cuticle.  Involved in heat-shock adaptation.
What are the official names of this protein?
Endochitinase 3, Chitinase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_FRATN
Sequence: MSDKIRLLEGKVSSVAMDKTVVVRAERYVKHPLYGKFVKKTTKYYVHDENNECKEGDVIKFKETRPYSKTKKWCLVDIIHREK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SYW_CAMJE
Sequence: MRVLTGLQPSGDLHIGNYFGAIKQMVDAQEKSQMFMFIANYHAMTSSQDGEKLKQNSLKAAAAFLSLGIDPQKSVFWLQSDVKEVMELYWILSQFTPMGLLERAHSYKDKVAKGLSASHGLFSYPVLMAADILLFDTRIVPVGKDQIQHVEIARDIALKVNNEWGEIFTLPEARVNEEVAVVVGTDGAKMSKSYQNTIDIFSSEKTLKKQISSIVTDSTALEDPKDHENCNIFKIAKLFLDESGQKELQIRYEKGGEGYGHFKIYLNELVNAYFKEAREKYNELLEKPSHLKEILDFGATKARKIAQEKMQKIYEKIGL
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_BRASO
Sequence: MTVTDIASRTYNHGWRLDPIVRSLLDTDFYKLLMLQMIREFYPDQKVTFSVINRTKRVRLGDVIDEGELRAQLDHARTIRFSKKELIWLAGNTFYGKTHMFSPDFLAWLANFRLPEYELHKADGQYELHFHGLWTHTTMWEIPALAIVNELRSRQAMKGQGRFALDVLFARAKAKLWAKVERLRKLEGLRLSDFGTRRRHGFLWQRWCVEAVKEGLGSSFTGTSNVLLAMDNDLEAIGTNAHELPMVAAALAKDDDELRFAPYRILDQWRQTYAGNLLIALPDAFGTKAFLRDAPDWVADWTGFRPDSAPPIQAGEEIIAWWKSKGRDPRQKLLVFSDAMDVESIEQIHQRFSDQVRLSFGWGTNLTNDFVGCSPDGSVDLDPISLVCKVTSVDGRPAVKLSDNPEKATGDPAEIARYLRVFGDAGRVRTPVFV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: TNNI1_MOUSE
Sequence: MPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I, slow skeletal muscle, Troponin I, slow-twitch isoform.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: NU4LM_DANRE
Sequence: MTPTHFSLNAAFMLGLAGLTFHRVHLLSALLCLEGMMLSLFISMALWTLKTESMSLSTAPMLLLAFSACEASAGLALLVATARTHGSDHMKNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AROD_ECO57
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLALLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: RPIA_XYLFT
Sequence: MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLCITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YPJD_ECOLI
Sequence: MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVCHAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALINLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKLAFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWFVYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS
What are the official names of this protein?
Inner membrane protein YpjD.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DING_ECOLI
Sequence: MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase (PubMed:12748189, PubMed:17416902).  Can also unwind DNA-RNA hybrid duplexes.  Is active on D-loops and R-loops, and on forked structures (PubMed:17416902).  May be involved in recombinational DNA repair and the resumption of replication after DNA damage (PubMed:17416902).  The redox cluster is involved in DNA-mediated charge-transport signaling between DNA repair proteins from distinct pathways.  DinG cooperates at long-range with endonuclease III, a base excision repair enzyme, using DNA charge transport to redistribute to regions of DNA damage (PubMed:24738733).
What are the official names of this protein?
ATP-dependent DNA helicase DinG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
Protein: MRAZ_CERS5
Sequence: MAEAFRGEYNQKVDAKARVSIPAPFRRVIEAGDPKYSGGRASFVLVYGGDRSYVECYTMTEMDRIEERIRALPMGTPRRRYLERNMITLALNMELDEDGRIVLPPKGREKLGITPDELKGGTEATFAGTLNKFQIWKADTYAAELAAEEEVILPPGADMLSLLEETGL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TRM2B_HUMAN
Sequence: MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR
What is the function of this protein?
Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and 12S rRNA (PubMed:31948311, PubMed:34556860).  Catalyzes the methylation of uridine at position 54 (m5U54) in all tRNAs (PubMed:31948311).  Specifically methylates the uridine in position 429 of 12S rRNA (m5U429) (PubMed:31948311).  Does not affect RNA stability or mitochondrial translation (PubMed:31948311).
What are the official names of this protein?
tRNA (uracil-5-)-methyltransferase homolog B, TRM2 homolog B, rRNA (uracil-5-)-methyltransferase TRMT2B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NEUL3_HUMAN
Sequence: MGAQLCFEANAKAPREALRFHAEAKGAQVRLDTRGCIAHRRTTFHDGIVFSQRPVRLGERVALRVLREESGWCGGLRVGFTRLDPACVSVPSLPPFLCPDLEEQSPTWAAVLPEGCALTGDLVRFWVDRRGCLFAKVNAGCRLLLREGVPVGAPLWAVMDVYGTTKAIELLDPTASRLPTPMPWDLSNKAVPEPKATPGEECAICFYHAANTRLVPCGHTYFCRYCAWRVFSDTAKCPVCRWQIEAVAPAQGPPALRVEEGS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a role in various biological processes such as lung development or innate immunity (PubMed:30111563).  Seems to utilize UBE2E1.  Promotes innate antiviral response by catalyzing 'Lys-63'-linked ubiquitination of IRF7 (PubMed:35792897).  Inhibits also hepatitis C virus assembly by directly binding to viral E1 envelope glycoprotein to disrupt its interaction with E2 (PubMed:30111563).
What are the official names of this protein?
E3 ubiquitin-protein ligase NEURL3, Lung-inducible neuralized-related C3CH4 RING domain protein, Neuralized-like protein 3, RING-type E3 ubiquitin transferase NEURL3.
Protein: MZRA_ENT38
Sequence: MVISPLALRRLSYGLIALVLLSALILVWTALQRQESTLAIRPVSQGASVPDGFYIWHHLDANGIQFKSITPQDDVLLIKFDSSAQSAAAKVVLDRSLPRGYIIALQDDQSQTAVWLTRLRDTSHRFG
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RSMA_ESCF3
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_ECOLI
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface.  In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 (PubMed:12809609).  In the 3. 5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA (PubMed:16272117).  The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation.
What are the official names of this protein?
50S ribosomal protein L19, Large ribosomal subunit protein bL19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL14E_METMP
Sequence: MAAIEVGRVCIKTLGREAGNTCVIVEVLDKNFVVIDGSVKRRRCNLKHVEPTDKKVDLEKAASTEEVKLALDAAGLL
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: ENP1_YEAST
Sequence: MARASSTKARKQRHDPLLKDLDAAQGTLKKINKKKLAQNDAANHDAANEEDGYIDSKASRKILQLAKEQQDEIEGEELAESERNKQFEARFTTMSYDDEDEDEDEDEEAFGEDISDFEPEGDYKEEEEIVEIDEEDAAMFEQYFKKSDDFNSLSGSYNLADKIMASIREKESQVEDMQDDEPLANEQNTSRGNISSGLKSGEGVALPEKVIKAYTTVGSILKTWTHGKLPKLFKVIPSLRNWQDVIYVTNPEEWSPHVVYEATKLFVSNLTAKESQKFINLILLERFRDNIETSEDHSLNYHIYRAVKKSLYKPSAFFKGFLFPLVETGCNVREATIAGSVLAKVSVPALHSSAALSYLLRLPFSPPTTVFIKILLDKKYALPYQTVDDCVYYFMRFRILDDGSNGEDATRVLPVIWHKAFLTFAQRYKNDITQDQRDFLLETVRQRGHKDIGPEIRRELLAGASREFVDPQEANDDLMIDVN
What is the function of this protein?
Required for normal export of the pre-40S particles from the nucleus to the cytoplasm.  Its subcellular location and association with pre-40S subunit shifts from mixed cytoplasm/nucleus to all nuclear in RPS19 disruptions, suggesting it acts after the ribosomal protein.
What are the official names of this protein?
Essential nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the bystin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: NRDR_CHLTB
Sequence: MLCPFCNHGELKVIDSRNAPESNAIKRRRECLRCSQRFTTFETVELTVQVLKRDGRYENFQESKLVNGLKAASSHTRIGQEQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFKDVGELMEVLLSATPDGEKQT
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CH601_VIBHA
Sequence: MAAKDVKFGNDARVKMLEGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFQNMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVIAAVEQPKRASVECTDTKAIAQVGTISANSDSSVGNIIAEAMEKVGRDGVITVEEGQALQDELDVVEGMQFDRGYLSPYFINNQEAGSVDLENPFILLIDKKVSNIRELLPALEAVAKASRPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGIVISEEVGLELEKVALEDLGQAKRVAITKENTTIIDGVGEEAMIQGRVAQIRQQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVEDALHATRAAVEEGVVAGGGVALIRAASKIVDLEGDNEEQNVGIRVALRAMEAPIRQITKNAGDEESVVANNVKAGEGSYGYNAATGEYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVTDLPQKEGAGMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_BLEDI
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, BleDi-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOA_ACTSZ
Sequence: MSKDTIFSAPIEKLGDFTFDENVAEVFPDMIQRSVPGYSNIITAIGMLAERFVTPDSQVYDLGCSRGAATLSARRNIRQPNVTIIGVDNSQPMVERARQHLNAYHSDIPVEILCDDIRNISIENASMVILNFTLQFLPPEDRQSLLEKIYRGLNPGGLLVLSEKFRFKDDTTNNLLIELHHAFKRANGYSELEVSQKRAALENVMRIDSSNTHKVRLKNVGFSHVELWFQCFNFGSVIAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: TSHR_RAT
Sequence: MRPGSLLQLTLLLALPRSLWGRGCTSPPCECHQEDDFRVTCKELHQIPSLPPSTQTLKLIETHLKTIPSLAFSSLPNISRIYLSIDATLQRLEPHSFYNLSKMTHIEIRNTRSLTYIDPDALTELPLLKFLGIFNTGLRIFPDLTKIYSTDVFFILEITDNPYMTSVPENAFQGLCNETLTLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLTAIDKDAFGGVYSGPTLLDVSSTSVTALPSKGLEHLKELIAKNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSIRNLRQRKSVNVMRGPVYQEYEEGLGDNHVGYKQNSKFQEGPSNSHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTVCGDNEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSPMALLGNVFVLFVLLTSHYKLTVPRFLMCNLAFADFCMGVYLLLIASVDLYTHTEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHAYTIMAGGWVSCFLLALLPMVGISSYAKVSICLPMDTDTPLALAYIALVLLLNVVAFVIVCSCYVKIYITVRNPQYNPRDKDTKIAKRMAVLIFTDFMCMAPISFYALSALMNKPLITVTNSGVLLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGLCKHQAQAYQAQRVCPNNNTGIQIQKIPQDTRQSLPNVQDTYEPLGSSHLTPKLQGRISEEYTQTAL
What is the function of this protein?
Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:1696008).  Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258).  The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).  Plays a central role in controlling thyroid cell metabolism (PubMed:12045258).
What are the official names of this protein?
Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: FLIP_BUCAI
Sequence: MKNNLFFQSISNSLHPIFNSEKFLQIMSSLSEIILLILIFSWILKKISSFKINKIISRMKIIERLSVGSQESIILVEVKQLRLLLGVTKKNISHLHTFPSNSKDELIKETNDTLLQKNLFDRSLKNFSKTSWKKTMFYRIIPFVFLLSLCPSAHADMPGLTSHILDDGSQTWSVPVQTLVFLTSLTFLPAFLLMMTSFTRIVIVFGLLRNALGTPYAPPNQILLGLALFLTFFIMSPTFEKIYKDAYVPFSQEKMNMEDAILKGSMPLKKFMLNQIRTPDLELFSKLAHISSYKNKNDIPMRILLPSFITSELKTAFQIGFTIFIPFLIIDLVVASVLMALGMMMVPPSTISLPFKLMLFVLVDGWQLLITSLAHSFNT
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.