PharMolix/UniProtQA huggingface dataset:
Protein: MAN1_DROME
Sequence: MSTESLNSLSDKELHRKLIQSGFPSTPVTETTRAVLIEKLRKHTRADKLKKRSNKYVLYSKEQQESPPFPQYHQYHAPQPPQNYANGLDNNNDLDQTGGSSAYNRSLDESDSSPLQLSASKMYAPPPVVASNYDGDCSPHSLGLNGKYLQPCSMPYAIDTSNNYGKPSGKAKLSDGGVVNRLLSFRDTTIQRKFNYPTGQASRIPLRKERLTRFALSDLKSFIRNPDIRPYVIPRVLISLFLIFLTIITVLYVGKRFEQSPIDKAALKYTLCNPNDMQMISEKVNCIEKDSLRGALDMSEELFRHLNERARLHHCKDANLSPALEIGEFVREMVSNPKTHRGNLHSNLMAAKYLITENPQWSIQVVDSTKHLGQTSHFELSEPNLPLKCIVLKKVTRFFTVIGALLLIVAGFLIVYVAVVIYRVKQKEALLAVDQFQKDIINELIYLSSQSESPEVVINQLQEKFLPAKKRSKLLSSWNKALKQLEKNDSRVLFGMVNRDGKAMRTIAWNRNVDKKDVGLVKKWQSPAFDNSNKIANPPTPCLKIRHMFDSSEVDQANLKQSIVESIIEKVGTRCKICDVQLDVQSCCVYIRCASEEDAGTIHKEINGWWFDKRLISIKFLRLERYLSRFPKPSAEPLYFHTNEAANTHS
What is the function of this protein?
Inner nuclear membrane protein (PubMed:16439308).  Acts as a negative regulator of the BMP (Dpp) signaling cascade during crossvein development in pupal wings and possibly during synaptic transmission at the neuromuscular junction (NMJ) (PubMed:18723885, PubMed:20036230).  Appears to be required for pupal development and consequently transition to the adult stage (PubMed:18723885, PubMed:20036230).  During pupal development, plays essential and redundant functions with the other LEM domain proteins; bocks and Ote (PubMed:24700158).
What are the official names of this protein?
Inner nuclear membrane protein Man1, LEM domain-containing protein Man1.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein. Cytoplasm. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=During anaphase and metaphase, detected in the nuclear envelope and spindle poles.
Protein: HYFI_ECOLI
Sequence: MSPVLTQHVSQPITLDEQTQKMKRHLLQDIRRSAYVYRVDCGGCNACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDHKICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQQKIHAVDYRDPTGVTMQPLWPQIPPSQRIAIEREARRLAGYRQGREICDRLLRHLSDDPTGNRVNTWLRDADDPRLNSIVQQLFRVLRGLHD
What is the function of this protein?
Possible component of hydrogenase 4.
What are the official names of this protein?
Hydrogenase-4 component I.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
Protein: VIRBA_BRUME
Sequence: MTQENIPVQPGTLDGERGLPTVNENGSGRTRKVLLFLFVVGFIVVLLLLLVFHMRGNAENNPHSYKTMVQTSTVPMRTFKLPPPPPPAPPEPPAPPPAPAMPIAEPAAAALSLPPLPDDTPAKDDVLDKSASALMVVTKSSGDTVVQTTNARIQALLDSQKNTKQDAGSLGTLLHGTQTDARMASLLRNRDFLLAKGSIINCALQTRLDSTVPGMAACVVTRNMYSDNGKVLLIERGSTISGEYDANVKQGMARIYVLWTRVKTPNGVVIDLDSPGADPLGGAGLPGYIDSHFWKRFGGALMLSTIETLGRYATQKVGGGGSNQINLNTGGGESTSNLASTALKDTINIPPTLYKNQGEEIGIYIARDLDFSSVYDVKPK
What are the official names of this protein?
Type IV secretion system protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y383_SULD5
Sequence: MEFKRKKEFKMIEKISKGLSLNKQKEQTVLEILPHEDENSKLLRLKRGSWESQKEPWLVYDEKGKLHALLSIETLSKMIEHFKNAEKETLFLKLEKSILQHLPLDFHDVWTVAMEEIKKSKKSDMDFDALIKKIKTEHPNLFLDLKDLYLPEGASVISTIER
What are the official names of this protein?
UPF0763 protein Sdel_0383.
What is the protein family that this protein belongs to?
Belongs to the UPF0763 family.
Protein: YP076_YEAST
Sequence: MKYNATKAISIAPPTIPTVNPTINEVFSFELLELELEEEEDKLLSCESDCFAQYVDGHLSHVNEVITQYSPEAQTGHDAVESQTTHPSLPLVAEVEEVAVLDKDELAEALEELDIFCLIFRKRT
What are the official names of this protein?
Putative uncharacterized protein YPR076W.
Protein: ACPS_DEIRA
Sequence: MIVAVGHDLIEIARIRRMLEREGVRAERLFTATELAYAGRYRDPAPSLAARFAAKEAFQKVWLRPHGWRDVWVERERTPDGPFPYAAPMLGFAPAIAGEMHERGWVAHLTLTHTREHASAVVILEHLEQRAAP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1053_BRUA2
Sequence: MSDVMTANRRSFLAEDGKETIVRTDDLVRDFDLGHRPEGGRLVLRAVDKVSLTIRRGETLGLVGESGSGKSTIGRMLVGLLPYTSGNIELFGQKIEPRAKAAAWKPLRRRVQFVFQDPHAALNPRMRVGTAIAEPLDVAGNLTRKERSARVDELMELVGLPTSFARRFPHEFSGGQRQRIVIARALALNPEILVCDEAVASLDVSMQAQIVNLLKDLQDQLGLSYLFIAHDLAVVRAVSHRVAVLYAGQIVETGPRTALYSDPLHPYSRALLDSVPRARRGAPRSIIAGEVPSLLNKPKGCAFCPRCPKAMDICRDVPPPLRVIGDREVACHLY
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative peptide import ATP-binding protein BAB2_1053.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRR_LEVBA
Sequence: MVKVVVDAMAMQRALTRITYEIIERNKGVDDLVILGIKTRGVYLARRIASRLQQLENVTVPVGDLDITPYRDDIDHDAQTEPEVTAANIDFSVEGKKVILVDDVLYTGRTIRAAMSAIMDLGRPKSINLAVLVDRGHRELPIRADFVGKNIPSSQRERIKVSVSEIDDRDAVEIQQA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: XYLA_BACFR
Sequence: MATKEYFPGIGKIKFEGKDSKNPMAFRYYDAEKMINGRSMKDWLKFAMAWWHTLCAEGGDQFGGGTKQFPWNGDPDPVQAAKNKMDAGFEFMQKMGIGYYCFHDVDLVTEADSIEAYEANLKELVAYAKQKQAETGIKLLWGTANVFSHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGTNYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYGRARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDQDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNFELTQAMMQIIRNDGLGNGGTNFDAKTRRNSTDPEDIFIAHIAGMDAMARALESAANLLNESPYQKMLSDRYASFDAGKGKEFEEGKLSLEELVAYAKANGEPKQTSGQQELYEALVNIYSL
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I63A3
Sequence: NTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQTVERILEEEFDEVLKMTIASGPASRYLTDMTLEEMSRDWFMLMPKQKMAGSLCIRMDQAIMDKDIILKANFSVIFNRLETLILLRAFTEDGAIVGEISPLPSLPGHTDEDVKNAIGDLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: MAF_PINFU
Sequence: ASMFKHDHYMDNGVRYPNGDGICKQLNETKCDAGFSYDRSICEGPRYWQTISKCFIACGIGQRQSPINIVSYDAKFRQRLPKLKFKPHMEKLKTEVTNHQNRAPEFEPEDGENLYVKLNNLVDGHYKFHNLHVHNGRTRRKGSEHSVNGRFTPMEAHLVFHHDEQTHFEPTRTKLGGAFPGHNDFVVVGVFLEVGDDGFGDEPDDEECKHILKGHHPDNNENGNGDNGNNGYNGDNGNNGDNGNNGYNGDNGNNGVNGNNGYNGDNGNNGDNGNNGENGNNGENGNNGENGHKHGCRVKKAKHLSRILECAYRNDKVREFKKVGEEEGLDVHLTPEMALPPLKYRHYYTYEGSLTTPPCTESVLWVVQKCHVQVSRRVLHALRKVEGYKDGTTLRKYGTRRPTQKNKVTVYKSFK
What is the function of this protein?
Acts as a negative regulator for calcification in the shells of mollusks.  May function both as a calcium concentrator and as a carbonic anhydrase required for production of carbonate ions, which are assembled to CaCO(3) at mineralization sites.  Is important for shell formation in both the calcitic prismatic layer and the aragonitic nacreous layer (By similarity).  Shows inhibitory activity of crystal formation when present in free state but, when attached to the insoluble matrix, may regulate the form and size of aragonite crystal.
What are the official names of this protein?
Nacrein-like protein F.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CCMD_RHOCB
Sequence: MMPEFGKYAVTILASWGATLVLLAGLIAATLIRGAQVKRALKAQEERMKNDG
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein D, Cytochrome c-type biogenesis protein HelD.
What is the protein family that this protein belongs to?
Belongs to the CcmD/CycX/HelD family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RECA_NITSB
Sequence: MDTNKQKALDLAIKQIDKAFGKGALVKLGDKQIEPIESISTGSLGLDLALGIGGVPKGRIVEIYGPESSGKTTLALQIIAEAQKKGGVAAFIDAEHALDVLYAKNLGVDIDNLLVSQPDFGEQALDIVETIARSGAVDVIVIDSVAALTPKAEIEGEMGDSHMGLQARLMSQALRKLTGVVHKMDTTVIFINQIRMKIGAMGYGTPETTTGGNALKFYASVRVDVRRIATLKQGESQIGNRVRAKVVKNKVAPPFRQAEFDIMFGEGISKEGELIDYGVKMDIIDKSGSWFSYKDIKLGQGRENAKAYLKEHPEVAQEIENEIRRAMGMDDSVMMVPENEMSEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI2_RHIME
Sequence: MSRALDKAGRWIGWAFFADLANGLALTFGYMFSRPVTMQYPDKEKWLPYSRYRGHHFLKRDDEGEIKCVACELCARICPCDCIEVVPYEDEKGNRRPAKFEIDTARCLFCGLCEDACPADAIALGQQYEFSSFSSRDLVIGRDDLLAKPGKAMTGGGVVAARLNTERDVLVEASEPRGYNWWRNIRRK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPD_MYCLE
Sequence: MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAVAMKMKVPTAAEVSELADVMLSHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQVANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLAGAKGPVRDAVVLNAAGAIVAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWVRFSQQV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: GREA_THEMA
Sequence: MKKVRLTREGYEKLKKELEDLKRKFMYEISERIKEARELGDLSENSEYEAAKNEQGRVGSRIMEIEQILSNAEIIEDSEESDEVTLGKWVVIKNLDTGEEHKFRIVTPQEADFFAQKLSSDSPLGKSLLGRKVGDVVKVKAPSGVQRYQVIAVMNK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RL1_STRMK
Sequence: MAQTKREKAIKAAVVPGKAYAFEDAINILKSATKAKFVESIDVAVRLGVDAKKSDQQVRGSTVLPAGTGKSVRVAVFAPAGAKADEALAAGAEAVGMDDLAEKMQAGDLNYDVVIATPDAMRVVGKLGTVLGPRGLMPNPKVGTVSPNPGEAVKNAKSGQVRYRTDKAGIIHCTIGKADFAEDALKSNLTALLLDLIKAKPATSKGTYLQKVSVSSTMGPGVTVDQSSLTLK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ACYP_MYCSJ
Sequence: MSAEPEVRLTAWVHGRVQGVGFRWWTRSRALELGLTGFAANKPDGRVQVVAQGSREECERLLGLLEGGDTPGRVDKVIADWSDAREQITGFHER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: FMT_SHEFN
Sequence: MKPLKIIFAGTPDFAARHLQALIDSEHDVIATYTQPDRPAGRGKKLTASPVKALALEHAIPVFQPASLRNEEAQAELAALNADIMIVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDTETGVTIMQMDIGLDTGDMLLKTHLPIEATDTSASLYEKLAEQGPKALVQALIGLSDGSLKAQKQDETLANYAEKLSKEEARLDWNKSAKQLWQDIRAFNPWPVSYFEHQQSVIKVWQADYSAELCSQAPGTIIAATKQGIEIATAEGKLMIKTMQLPNKKPLDVADILNARGDWFTAGVCLNQEAN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MURG_STRPQ
Sequence: MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS9_TROWT
Sequence: MVPPQRAKNDTSSAPDSAAETRGPLVSSGSGLGRRKSATARVYLSPGEGVFVVNGRDINEYFTSKLHRQFACQPLKILDLLGSYDVKVTLHGGGASGQAGAVRLGIARALNTIDPENNRKPLKSAGFLTRDSRVKERKKAGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RIMO_FERNB
Sequence: MAFLKLYVIVLGCAKNEADFSLFKYHLKQLGHEVVDDVEDADGVVIDTCGFIVDAKQESIDTILEFASIKKQKPDFKVYVTGCLVQRYPKDLPLEIPEVDGWFGVIPPKNLAESINKTKKYITDPVAVYEFEGRVDSDLPYAYVKIADGCDRACTFCTIPKFKGGFVSRKLEDIEKEVRYLIENGKKEIVLVAQDTTGYGVDLYGKQMLPELLKRINDIDGNFWIRVMYMHPDHVTDEILKGFSYEKVVKYFDIPIQHSSDNILKLMGRTKSTKELEELFDKIRSLYPQAVLRTSIIVGFPGETKDDFEQLIDFIRTIEFDRLGGFVYSDEEDAASYNLPNKVSLKTAQKRLDTLMEVQAEISFLRNQRLVGKVIDVLFEEEVNGVIIGRSYMDAPEVDGNVFVKGHGINRFGKVKITEADTYDLEGELVE
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_BACHK
Sequence: MEFVFLGTGAGVPSKGRNVSAIALQLLEERGQTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIKQFIEVALSVSTTHVKYPLEIVEITEEGTVFEDNEFHVETKRLSHGIECFGYRIIEKDIQGALLVDKLLEMGVKPGPLFKRLKDGEVVELENGTILNGNDFIGPPQKGRVITILGDTRYCEASRELAQDADVLVHEATFAAEDEQQAYDYFHSTSKQAASIALQANAKRLILTHISSRYQGDTYKELLKEARELFSNTEIATDLKSFPVDR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ISPE_PROMP
Sequence: MSKLSTTKICVKSPAKINLHLEIIGKRKDGYHELAMIMQNIDLSDYIEFENNQIGEIKLKSNSKDLSLDEDNLIIKAANYIKDMSKNKELGANIFLKKNIPIGAGLAGGSSNAAATLVGLNKLWDLDLDYETIFILSAKLGSDVPFFIEGGCQFCFGRGEILEKYSSNFDFGVILLKNPNISISTVDTYKKYSQEFCPKYFTETEKTNKIRNDLRVNGFNDFKLSEQRINVKNDLQVIVERENNSVKKALYLLSNLQNCLSYSMSGSGPTCFALFKDINIANEVFEQNYKMFNNNGFEAWVCKLINSGITLL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL3_ALIFM
Sequence: MIGLVGRKVGMTRIFTEEGVSIPVTVVEVEANRVSQVKTVETDGYNAIQVTCGSKKANRVSKPEAGHFAKAGVEAGRGLWEFRLENGEEFAVGAELTVEVFNEIKKVDVTGTSKGKGFQGAVKRWNFRTQDMTHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAERVTTQNLEIVRVDAERNLLLIKGAVPGSTGGNVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HPRK_CLOP1
Sequence: MGVTIEKLIKDFSLEVIQTGEENVPINVSDVNRPGLQLAGFYNYFAPERIQVIGKAEWSFLEDMSPDLRKKRLNKFFSFDISCLIITRGLEIHEELLKAARKRNLWILRSDMVTTKFISKITMYLSDKMAPETRLHGVLVDVYGIGMLITGESGIGKSETALELIKRGHRLVTDDAVDIKEIDGDLIGRSPEITFGMLEVRGMGIIDVSALYGLSSILNSKQIKIIIHFEHWKDDGDYDRLGVNDEYQDILGVKVKKLRVPIRPGRNIAVIIEAAAANYRYQRMSDISPVDIIEKRMLESMEKESKI
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: SYS_ECO55
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTS2_ONCHC
Sequence: MLCLSLNSSSTSPPKLPLHHSFSRRGIRSWVRSPCVQRKKLGFWSSPKAVLSAVSGAGSEAGKVEEAEEYDAIVIGSGIGGLVAATQLAVKGARVLVLEKYVIPGGSSGFFQRDGFTFDVGSSVMFGFSDKGNLNLITQALEAVDCKLRTIPDPTTVHFHLPDNLSIRVHREYDMFISELVNYFPHEKEGIRRFYNECWKIFNSLNSLELKSLEEPMYLFGQFFRKPVECLTLAFYLPQNAGDIARKFIKDPQLLSFIDAECFIVSTVKALHTPMINASMVLCDRHFGGINYPVGGVGGIAKALANGLVNKGSKLLYKANVTKILLKDGKAVGVKLSNGREFFAKTVISNATRWDTFGKLLKVEDIPQEEKNFKKIYLKAPSFLSIHMGVKAFVLPPDTDCHHFILEDNWGRLELPYGSIFLSIPTVLDPSLAPEGHHIFHIFTTSSIENWEGLSHKEYEEKKELVADEIITRLEKKLFPGLKDSVVLKEVGTPKTHRRFLARDSGTYGPMPRKVPKGLLGMPFNTTAINGLYCVGDSCFPGQGVIAVAFSGVMCAHRVAADLGFEKKAPVLDAALLRLLGWLRTVA
What is the function of this protein?
Carotene cis-trans-isomerase that converts 7,9,9'-tri-cis-neurosporene to 9'-cis-neurosporene and 7,9,9',7'-tetra-cis-lycopene (also known as prolycopene) into all-trans-lycopene.  Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds.  Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis-double bonds at C9 and C9' (By similarity).
What are the official names of this protein?
Prolycopene isomerase 2, chloroplastic, CrtISO2, Carotenoid isomerase 2, OcrtISO24.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein.
Protein: PTSN_BRADU
Sequence: MPITDLVAPEAILPALKVNSKKQALQELAAKAAELTGQNERAVFEVLLQREKLGTTAVGYGVAIPHGKLPKLEKIFGLFARLDRPIDFESMDGQPVDLVFLLLAPEGAGADHLKALARIARLLRDQDIAKKLRASRDAQAIYSVLALPPATAA
What is the function of this protein?
Seems to have a role in regulating nitrogen assimilation.
What are the official names of this protein?
Nitrogen regulatory protein, Enzyme IIA-NTR, Nitrogen-metabolic PTS system EIIA component.
What are the subcellular locations of this protein?
Cytoplasm.