PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_NOCFA
Sequence: MAELTISSDEIRSAIESYTQSYTPETSIEEVGVVTDTSDGIAHVSGLPSAMANELLEFPGGVLGVALNLEDREIGAVILGEFAEIEEGQQVRRTGDVLSVPVGDKFLGRVVNPLGQPIDGLGEIEAEEQRVLELQAATVLQRQPVEEPLATGITAIDALTAIGRGQRQLIIGDRKTGKTAVCIDAILNQKANWETGDPTKQVRCIYVAIGQKGSTIAGVKAALEEHGALEYTTIVAAPASDSAGFKWLAPYTGSAIGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEMGGGSMTGLPIIETKANDISAFIPTNVISITDGQVFLESDLFNKGVRPAINVGTSVSRVGGAAQTKGMKKVAGSLRLEMAQYRELEAFSAFASDLDAASLAQLERGARWVELLKQDQYSPVPVEDQIVSIFLVDQGYYDSVPVGDIRRFNAELLEDLHRSAADAFKSIEGGKVLEGEAAEAIKAATDKFKQGFLASDGSRVVNEAAAGELGHEEVESLSVTRKHVEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLMM_AROAE
Sequence: MPATPPNRLGLTASGLLALCRAGFEKEVAAELDDFAAGIGLTGFVRTRPGSAFVTFETHEPVAFADLAERCDWRTLIFARQLLPWFARVDDLPERDRATPIATATRNAGQRFAQLMLETPDTDEAKQQSGFCRRFTVPLQHELERIGAFREGAKGLPELHILFPDTSTAWLCAALPGQAALWPMGIPRLRMLREAASRSTLKLAEAIFTLLSETERNASLRAGLRAVDLGAAPGGWTWQLAHRGLRVTAVDNGPMAPSVMATEMVEHVRADGFTWRPQRPVEWMVCDMVEQPTRIAALVADWIATGRCRRTIFNLKLPMKKRLEAVEQCRALITKRLAQAGPFELRFKHLYHDREEITGYLALRAAAV
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_GEOKA
Sequence: MSSIRLYNTLTRKKEPFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRGYDVTYVSNFTDVDDKLIKAARELGESVPAIAERFIEAYFEDIQALGCKKADIHPRVTENIDTIIEFIQALIDKGYAYEVDGDVYYRTRKFREYGKLSHQSIDELQAGARIEIGEKKDDPLDFALWKAAKEGEICWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEIAQSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIREIDPQVLRFFMLSVHYRHPINYSEELLESARRGLERLKTAYSNLQHRLQASTNLTDNDEEWVSRIADIRASFIREMDDDFNTANGIAVLFELAKQANLYLQEKTTSEKVIHAFLREFEQLADVLGLTLKQDELLDEEIEALIQKRNEARKNRDFALADRIRDELRAKNIILEDTPQGTRWKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_ACTPJ
Sequence: MTQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEGRLRAIGIEVFNANEVSELDVYIDGADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGSKQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREGVVTDNGNVILDVHNFHIIEPLKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SGAT_WHEAT
Sequence: HLFVPGPVNIPDQVLRTLLEDVKKLASRLRSDSQHTIKLLDAYRVFFDWKDYLKKVFRNVNTLLKDLGYPVKPLIPSR
What are the official names of this protein?
Serine--glyoxylate aminotransferase, SGAT, Alanine--glyoxylate aminotransferase, AGT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: LPXB_HELAH
Sequence: MPTILVSALETSSNVHLEELRRNLPKDYRFIGVFEGSGALYSPREFSVMGFRDVIGRLGFLFKVYKEMIQLAKQADMVLLMDSSSFNIPLAKKIKKQDSHKKIMYYILPQVWAWKKWRAKTLEKYCDFLGAILPFEVSYYQKKAQYVGHPLLDEIKYYKKDIKGETLVFMPGSRKSEIAKIFPLFVEVARILEQNEGFKRRVLVVPSFFKGLDLKALYGEGIEWFEISYDAHKSLFEAEFAFICSGTATLEAALIGTPFVLAYRAKTMDFLIARMFVNLHYIGLANIFYNALNDETPGLGESQLHPELIQHFLSVESLIRAYKDMDRERYFKESLKLREYLMHGSARKIASEIAFLLNLT
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ART10_ZYGRC
Sequence: MSPQIKLYLNPPKNNQYYSNHDHISGSVSVDFGKPVSIKQINVSFKGFIETMTKIDPVVMRNQAALMSPMQDAKTIHTLVNIGQKVFPPENVLSAIEGDLKPFQLKEGVHEYEFQLPKVPKKPKCLSSHTKGLMTYLDKDRVRLPPSFNNDWKNMLRFDNLDLFFYSFGKILYMVEVQIELGKPKSWYRPFEKVLTEIQLVEFIPQSKDLTFKLDDKPSKEVLESFKNSNGEQEEKTSNKLQTEKATVPTNAPLVDVMTQKPDVRVYRSTYKIGLPDDDSVMWLEARSPNLRRTFRGDPIFAGGSGKFDDIYIVMMGDKALIDRLRVIPTRVQLNLLETVTYLSQGVANQNVSSLKLAEDRIPLEKRSTVLKNSWGRYVQFSSSNPNQCKWECELRLKNHPNLKKLKFNEEDYRHRGNRLYSFKSCSIKRIFSFQLLVDWDIVGFKRQSEIIVDPIQVFADRNGRNQEEALPLYVPPPSYTESTQY
What is the function of this protein?
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
What are the official names of this protein?
Arrestin-related trafficking adapter 10.
What is the protein family that this protein belongs to?
Belongs to the ART10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPPRC_HUMAN
Sequence: MAALLRSARWLLRAGAAPRLPLSLRLLPGGPGRLHAASYLPAARAGPVAGGLLSPARLYAIAAKEKDIQEESTFSSRKISNQFDWALMRLDLSVRRTGRIPKKLLQKVFNDTCRSGGLGGSHALLLLRSCGSLLPELKLEERTEFAHRIWDTLQKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTVMRDAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCERRYIPDAMNLILLLVTEKLEDVALQILLACPVSKEDGPSVFGSFFLQHCVTMNTPVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGFPIRPHYFWPLLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDSDMFSQAGLRSEAANGNLDFVLSFLKSNTLPISLQSIRSSLLLGFRRSMNINLWSEITELLYKDGRYCQEPRGPTEAVGYFLYNLIDSMSDSEVQAKEEHLRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQKTVQLTSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESDMVTGGYAALINLCCRHDKVEDALNLKEEFDRLDSSAVLDTGKYVGLVRVLAKHGKLQDAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNISFPLVTVHLEKGDLSTALEVAIDCYEKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMVMLYDLFFAFLQTGNYKEAKKIIETPGIRARSARLQWFCDRCVANNQVETLEKLVELTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAEILREGNQEVPFDVPELWYEDEKHSLNSSSASTTEPDFQKDILIACRLNQKKGAYDIFLNAKEQNIVFNAETYSNLIKLLMSEDYFTQAMEVKAFAETHIKGFTLNDAANSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLNGLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIENMLTSENKVIEPQYFGLAYLFRKVIEEQLEPAVEKISIMAERLANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKASTVKSVLELIPELNEKEEAYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYASLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS
What is the function of this protein?
May play a role in RNA metabolism in both nuclei and mitochondria.  In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export.  May bind mature mRNA in the nucleus outer membrane.  In mitochondria binds to poly(A) mRNA.  Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits.  May be involved in transcription regulation.  Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors.  Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP.  Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters.  Binds single-stranded DNA (By similarity).
What are the official names of this protein?
Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Note=Seems to be predominantly mitochondrial.
Protein: YNCE_SALTI
Sequence: MHLRHLFSPRLRGSLLLGSLLVASSFSTLAAEDMLRKAVGKGAYEMAWSQQENALWLATSQSRKLDKGGVVYRLDPVTLEITQAIHNDLKPFGATINAATQTLWFGNTINSAVTAIDAKTGDVKGRLVLDARKRTEEVRPLQPRELVADAATNTIYISGVGKESAIWVVDGETIKLKTTIENTGKMSTGLALDSKAQRLYTTNADGEFITIDTASNKILSRKKLLDDGKEHFFINLSLDTAGHRAFITDSKATEVLVVDTRNGNILAKIAAPASLAVLYNPTRNEAYVTHRQAGQVSVIDAKTYNVVKTFDTPTYPNSLALSADGKTLYVSVKQKSTREQEATQPDDVIRIAL
What are the official names of this protein?
Uncharacterized protein YncE.
Protein: RIMP_MYCS2
Sequence: MAPDPKLPSADLPSQKQVIELLDGEFARAGYEIDDVVVNAATRPARITIVADGDKGLDLDAVAMLSRLASGLLDTVDTGDTPYVLEVTSPGVDRPLTTEKHFRRARGRKAELSLADGSSLTARLGGTDGDQVNVVVAQGKDFAVRQIPLREITKAVVQVEFSPPNRRELELAEQTGKGARA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLC_BACSU
Sequence: MKYTFNEEKAFDIVAIGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGSAKLGLKAGFIGKIPDDQHGRFIESYMRKTGVDTTQMIVDQDGHKAGLAFTEILSPEECSILMYRDDVADLYLEPSEVSEDYIANAKMLLVSGTALAKSPSREAVLKAVQYAKKHQVKVVFELDYRPYTWQSSDETAVYYSLVAEQSDIVIGTRDEFDVMENRTGGSNEESVNHLFGHSADLVVIKHGVEGSYAYSKSGEVFRAQAYKTKVLKTFGAGDSYASAFIYGLVSGKDIETALKYGSASASIVVSKHSSSEAMPTAEEIEQLIEAQS
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: NUOCD_PSYWF
Sequence: MVTDNSKATDNSANPNMTQHAVLRELGHKFAGKFTEQFTFDGIPTIWVSRQDLLDVLMYLRTLPKPYVMLLDLSAMDERLRQHRDGLPASDFTVFYHLMSLERNSDIRVKVALSEDDLKVPTATKIWPNANWYEREVWDMFGIVFDGHPHLTRILLPKYWEGHPLRKEYHARATEFTPYFLNNAKQQFEQENLRFVPEEWGMKRSGRDEDFMFLNLGPNHPSAHGAFRLVLQLDGEEVIDCIPDIGYHHRGAEKMAERQTWHSYIPYTDRIDYLGGVMNELPYVMAVEQLAGITVPERAQTIRVMMSEFFRITNNLLYFGTFIQDAGGMTPVFYMFTDRQKAYDVIEAVTGYRMHPAWFRIGGTAADLPRGWQRLVREFLDWMPQRLDEYVKAAMENSVLKGRTQNVAQYDAKQALAWGVTGAGLRATGVEFDLRKARPYMGYENYDFEIPVGYNGDAYDRCMVKIEEIRQSLRIIRQCMDNMPSGPYKADHPLAVPPPKNRTLNDIETLINHFISVSWGPVMPAGEASMMVEATKGINSYYITSDRSTMSYRTRIRTPTFAHLQQMPSVINGSLVSDLIIYLASIDIVMADTDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: POLIA_ORYSJ
Sequence: MAVAPPLPPAPARQLRRWKGSSPRPPPWLSSPFRRTRYLSRPAFAAGGRQDYSPSSGMGVSKTGAFRLGLYGNLNVQSSVQEWVDETKRLFFLRTTNSVRNNITNGTTPLRVGNLRHDPSEDIRSSNYPSLYNQRERGPSNSIVNRHVDTDLAKHRVMYQSAHAVPAPFSVVNNDIKPLNMLDGSKEEIPWHDSVTMESSLPKVSKSEKTLVVDKAIPDKKEHKRITRKVTPNFPDKASLSTESKNARKLLATIYDKVLVVDNVESARSVVKLLTTKYKGFIHACDTEVANIDVKEETPVGHGEVICFSICSGNSDGEADFGNGKTCIWVDVLDGGRDVLMEFAPFFEDPFIKKVWHNYSFDIHVIENCGIKVAGFHADTMHLARLWDSSRRTDGGYSLEGLTNDYRVMDAVLKDIPKTGKVSMKTIFGRKKVRKDGSEGKTISIEPVEKLQREDRELWICYSSLDSMSTLKLYESLKNKLEAKEWIFDDCPRGTMYDFYEEYWRPFGALLVKMETEGVLVDRAYLSEIEKAAVTERELAADKFRKWASKHCPDAKYMNVNSDNQIRQLFFGGIENRNKRGETWPQSKTFKVPNDEGIATEGKKTPKSRTIKLFTIVEDLKIDMFTPTGWPSVSGDVLRSLAGKIPTDHIYKIDDGQEFDEDGSSLELPEQDIEDTSPYGTAYEAFGGGKKGREACHAIAALCEVFSIDKLISGFIVPLQGDRISCKEGRIHCSLNINTETGRLSARTPNLQNQPALEKDRYKIRHAFVAAPGNTLIVADYGQLELRILAHLTNCKSMLEAFKAGGDFHSRTAMNMYQHVRDAVEEKKVLLEWHPQPGQDKPPVPLLKDAFGAERRKAKMLNFSIAYGKTAVGLSWDWKVSVREARDTLKLWYRDRKEVSAWQKKQKAFALEKCEVYTLLGRSRQFPNMTHAGPGQKGHVERAAINAPVQGSAADVAMCAMLEIERNARLKELGWRLLLQVHDEVILEGPTESAEEAKTIVVECMSKPFYGTNILKVDLAVDAKYAKSWYAAK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity).  May be required for DNA replication and accumulation in plastids.
What are the official names of this protein?
DNA polymerase I A, chloroplastic, DNA polymerase PolI-like A, OsPolI-like A, DNA polymerase gamma 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SC4AB_TAKRU
Sequence: MRTLLPPVGSEVFRRFTQSSLNEIQQKQQIREEERKRTNAQVSEELPEPASDLEAGKPLPFIYGEPPHELLNVPLEDIDPFYQSQKTFIVLSKGNIIYRFNAESSLYLLSPFNALRIVAIKILIHSLFSLFIMATILTNCAFMTLSDPPAWSKTMEYVFTFIYTFEATIKILSRGFCVGKFTFLKDPWNWLDFMVISMAYLTELVDLGNVSVLRTFRVLRALKTITVIPGLKTIVGALIQSVRKLADAMVLTVFCLSVFALIGLQLFMGNLRQKCVLIPQWLYGNLTFDINSTNGYYGNDTHDNGTKSKHLEFEFERHINNPDNYYYLTGQGDPLLCGNSSDAGVCPESYVCLKVGANPNYGYTSYDSFGWAFLALFRLMTQDFWENLFQLTLRTAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYAEQNEATLAEAKEKEEEYIHILEALKKREEEQAARKEPHSTVEGFEDDHRLCPPCWYAFANIFLKWDCCGCWRHLKECLYAIVMDPFVDLGITICIILNTVFMAMEHYPMSADFEELLSVGNLVFTGIFTGEMVFKILAMDPYFYFQVGWNIFDSIIVTISLVELGLANVQGLSVLRSFRLMRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYKDCVCRISEDCVLPRWHMNDFFHAFLIIFRVLCGEWIESMWDCMEVSGQTMCLIVFMMVLVIGNLVVLNLFLALLLSSFSGDNLTTQDDEGENNLQIAINRINRAMSWTKTYILLYVYTLTESNLNQHFAVSDDEEQRRVKDILALTSVSSDKLVSHHCGNDFFRVPIAEAESDSDDSDYDEDKDSQCDESSVCSSVQKPEVQEEEMDENCVAKTPTDCWTKKCYSRCPFLDIDTSQGRGKIWCNIRRTCFSIVENNYFESFIVFMILLSSGALAFEDIYLEKHQLIKSILEYADKVFTYVFVMEMVLKWFAYGFKSYFSNAWCWLDFLIVDVSLVSLTANILGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAVPSIFNVLLVCLIFWLIFSIMGVNLFAGKFSYCFNETSQEIIDTKVVDNKTECIALIKANFTEVRWKNVKVNYDNVGIGYLSLLQVATFKGWTDIMYAAVDSRDVESQPIYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKAKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPVPRPENPFQGLVFDLVTKQIFDVFIMVLICLNMVTMMVETDEQSDKKEEVLYWINVVFILIFTTECTLKIIALRRHYFSIGWNIFDFVVVILSILGLLLADIIEKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEALIDDMFNFETFGNSMICLFMITTSAGWDGLLSPIMNTPPDCDPNVENPGTTVRGNCGSPAIGIAFFSTYIIMSFLVVVNMFIAIILENFNVATEESSDPLCEDDFEMFYETWEKFDPDASQFIQYSKLSDFCDTLKEPLRIPQPNTIKLISMDLPLVPGDRIHCMDILLALTAEVLGDSDEMDTLKATMEEKFMANNPSKVSYEPISSTLLRKEEEVAATVIQRAYRKYLLLRTVRLASFMYREKTEGRGKEKAPETTGLLCKQFSQLYGFNKETDEPLQSKANRLGQVELQSEVLLHAVPPLRSSEFLQERDQRETSV
What is the function of this protein?
Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient.  Alternates between resting, activated and inactivated states.  Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.
What are the official names of this protein?
Sodium channel protein type 4 subunit alpha B, Voltage-gated sodium channel subunit alpha Nav1.4b.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIAG_BACSU
Sequence: MKKMLGKLLITAGILVFFAVVVKDVFAAGLGFINGTEADSASASPRDIDSMVIESDSKDVRIIAEERSDISAGISGDSGKLFVTENKRKLELTVKEKEFQFLNGFNRSTLIVRLPYDYKGDLAVRTSSGDVSVAGNDHLALSGLNAVSASGNTSVTDVRIQDLKVKASSGDVSISNTVSKTAGIDLASGDANLVHVSGSLDVKMTSGDFNAVLKKVTGPVSVTLTSGDANVSLPQNGSFAVNALSASGDVSSPYSFADKGHKEQHHITGTQGSGRHPIDIKTDSGDLAIR
What are the official names of this protein?
Protein LiaG.
Protein: DCHS_CLOP1
Sequence: MNKNLEANRNRTLSEGIHKNIKVRAPKIDKTAISPYDRYCDGYGMPGAYGNGYVSVLKVSVGTVKKTDDILLDGIVSYDRAEINDAYVGQINMLTASSFCGVAGQVWGHDLATHDSIANDEIKPLYELKQFDGTPLKVYDAKPLLEAGIELFGTEKNRRFTTAPGAHVICANKSATAYRPKENRPLKEGEAYGVWSFIALSLSNDRDHCADLFIEDAGLWTKNDNPEDLKKFLEDHRKAVTWSVVECGRDSHVVFERTYIGFAYVIMKPGEIGNALTCAPYVTLARDAVPSEGFPSLNRISLSQWLDDMNFDSLVNPSKK
What are the official names of this protein?
Histidine decarboxylase proenzyme, Pi chain.
Protein: Y2229_MYCTU
Sequence: MKAGVAQQRSLLELAKLDAELTRIAHRATHLPQRAAYQQVQAEHNAANDRMAALRIAAEDLDGQVSRFESEIDAVRKRGDRDRSLLTSGATDAKQLADLQHELDSLQRRQASLEDALLEVLERREELQAQQTAESRALQALRADLAAAQQALDEALAEIDQARHQHSSQRDMLTATLDPELAGLYERQRAGGGPGAGRLQGHRCGACRIEIGRGELAQISAAAEDEVVRCPECGAILLRLEGFEE
What are the official names of this protein?
Uncharacterized protein Rv2229c.
Protein: V060_FOWPN
Sequence: MYTRYKLSILFFVINFYNILCMPLSCETECCMAGKKYDDAAIDRDLCVLLCNLQYLASSNEGIGEILQCCLSSNYTSKTREDLRNCIAKCPPLPDRGCTGECCDLRENVDSLRANNPLGCCNDYTKVSSSSLNEDDVIDCRKSDASCEDRGYLLVRNNGSAVCIPENSKNDNIGFYFGSECSDLSRKG
What are the official names of this protein?
Putative CC-type chemokine FPV060.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family. Highly divergent.
Protein: KKCC2_HUMAN
Sequence: MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQRRQPPGHRPAPRGGGGSALVRGSPCVESCWAPAPGSPARMHPLRPEEAMEPE
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes.  Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4.  Isoform 3 phosphorylates CAMK1D.  Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive.  Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1.  This phosphorylation is stimulated in response to Ca(2+) signals (By similarity).  Seems to be involved in hippocampal activation of CREB1 (By similarity).  May play a role in neurite growth.  Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, neuron projection. Note=Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction.
Protein: RS9_DROYA
Sequence: MVNGRIPSVFSKTYVTPRRPYEKARLDQELKIIGEYGLRNKREVWRVKYALAKIRKAARELLTLDEKDEKRLFQGNALLRRLVRIGVLDESRMKLDYVLGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNLKKNQGGGGGAAEEEED
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PLSX_PSET1
Sequence: MLNNLTIALDMMGGDYGPRSSIPAAVNAVNAHANLTLILCGNEQVISKQLESLDSLAHPRLIIRHCSEVVTNACKPGVAVRSKKDSSMRVALNLVKSGEAQACVSSGNTGALFFMAHYVLKMLPGVKRPALISAVPTERKNPVYLLDLGANVHCDAQTLYQFGIMGSVVAGQALGCDNPKVSLLNIGSEDIKGHEDIKQAAQLMQQSPLINYIGYSEGSDIFTGKADVIVCEGFVGNVALKTCEGIAKLIMNKFTAALEKHLVYKCMAFMLSPIIKKLYKRVNPDQYNGASLVGLRGIVVKSHGNASAKAFQAAIDEAVKEVERQLPDKIAAIFEKIHSKDTVNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: T23O_ERYLH
Sequence: MAQDVTYSSYLDLDRILAAQHPVSGAHDEMLFIIVHQASELWLKLCLHELFAARDCIAADNLRPSFKMLSRVARAQTQLIQSWDVLSTMTPHDYSQIRPHLGRSSGFQSPQYRMMEFLLGGRNPDMVAMHEPTPEIATALREELARTSLYDEAIRLLSRRGFAIPDEVLARKLDEVWVRSEEVEAAWAEIYRDPQQHWDLYELAEKLVDLEYHFQRWRFGHLKTVERIIGFKRGTGGTKGVPYLEGVLKQAFFPELLSVRTAI
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: LLDD_ECO8A
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPTALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNS2A_MOUSE
Sequence: MATLRSLLLAALLWVPAEALSCYGDSGQPVDWFVVYKLPAHSGSRDTPKGLTYKYMDQNSDGWQDGVGYINSSEGAVGRSLQPLYRKNSSQLAFLLYNDQPPKSSSARDSTGHGHTKGVLLLDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYTYPLVYDHKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVILTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPGILPSNCSGAYQVLDVTQTGFPGPSRLTFSATEDHSKWCVAPQGPWACVGDMNRNKAETHRGGGTVCTQLPSFWKAFQSLVKDWKPCIEGS
What is the function of this protein?
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA.  Plays a major role in the clearance of nucleic acids generated through apoptosis, hence preventing autoinflammation.  Necessary for proper fetal development and for definitive erythropoiesis in fetal liver and bone marrow, where it degrades nuclear DNA expelled from erythroid precursor cells.
What are the official names of this protein?
Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RL30E_METMA
Sequence: MRRELMKMKINVDKSLIKAVKTGKVIIGANRTVDAAENGSAKMVVLASNCPADIKKKVQETNVPVLEYEGTSVELGPVCGKPFTIAAMAILDAGESDILAATA
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: Y039_TREPA
Sequence: MRQENKPCQQFYFVLDEKALQSPLRENPSKNVRTIPDAGDENSSFGHARVIA
What are the official names of this protein?
Uncharacterized protein TP_0039.