PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_PELUB
Sequence: MLKNAQKDFIQRHIGPSVDEQNVMLKELGYQNLDDLIKDTVPEKILLKDDLDIGDPNSEYKALRKLKDISKKNKIYSSFIGMGYYGTYTPYVILRNILENPGWYTSYTPYQPEVAQGRLEMLLNFQQMIIDFTGMDIANASLLDEGTAAAEAMGLSYRISKSESKKVFVSKNCHPQTIDVIKTRAEPLGLEIIVGDEDKDIKEDIICGIIQYPGTLGDIKDPSEAISKIHKFNGKAVLACDLLALAKLKTPAELGADIAVGSSQRFGIPMGYGGPHAAFFATKDEYKRSMPGRIVGVSVDRHGKKAYRLALQTREQHIRRDKATSNICTAQALLAIVSAAYAVYHGPQGIKKIAESVSQLTKNFADKLKQSGYELYSNEFFDTVTIKTLDKTEKIYKNALDQGVNIRKVNSEMLAVSFDERKNLYRANQLLKIFNCSETIKETMNESLSNIPKNLLRTSTYLDHPVFNSYHSETEMLRYLKKLEDSDIALNKSMIALGSCTMKLNAVAEMIPVTWKEFSQPHPFSPVEQMDGYRELFTDLKNWLRSITGFSGVSLQPNAGAQGEFAGLMVIRKFHEKNGETNRNVCLIPSSAHGTNPASAQMVGMKVVVVKCDQYGNVDYEDLKNKAEEHSENLAALMVTYPSTHGVFEEKITDICELIHNHGGQVYMDGANLNALVGIAKPGNFGPDVCHINLHKTFCIPHGGGGPGMGPIACKKHLEIFLPKHSVIKDCGPVTGMGAVSAAPWGSSSILSISWMYIKMMGSEGLRKASQVAILNANYIAHKLKDSFPILYKGKSGNVAHECIIDIRTIKSETGITEEDIAKRLIDFGYHAPTMSWPVAGTMMIEPTESESLSEIDKFCSTLIKIKQEIDKIQSGEYDKTDNPLKNAPHTHVELTSNKWDHKYEREEAAYPSEFLRTNKYWPPVGRVDNVYGDKNLFCTCPSMEEYEDTAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: HM13_CAEEL
Sequence: MSSTECYGAPPHNYYQDWPTTHSYYPSVPSSYSPLNHHPADIWAAHPSNYIMGNGHVSPPATASGLSPPASRSSNSSAELPTGVTASQHNTYKWMHTKRSQRPAAPKKKVIDENGTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKIWFQNRRMKEKKREKEKAFLARNTWESNSPTSSCSGEDVKNFK
What are the official names of this protein?
Homeobox protein ceh-13.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPYD_PONAB
Sequence: MAPVLSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTPDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPFLPPPEKMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEAMSPIKFNRWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYIQSQYGASVSAKPELPLFYTAIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSTARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIRLKEQNIASSPHKRNCFIPKRPVPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTITDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPLSVNPVC
What is the function of this protein?
Involved in pyrimidine base degradation.  Catalyzes the reduction of uracil and thymine.  Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
What are the official names of this protein?
Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the dihydropyrimidine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BURTA
Sequence: MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQTTLQAGEPQQKVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYSPAQLTEASNYINAHFAGLSFDEVRRRLRGEIDELRGDMTALMHAAVTASTEEPADEETVLISGERNLLEVADLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ACDA1_METMA
Sequence: MSKLTTGSFSIEDLESVQITINNIVGAAKEAAEEKTKELGHMGPTPFPGLETYRDDWNLKLLDRYEPVVTPMCDQCCYCTYGPCDLSNNKRGACGIDMLGHNGREFFLRVITGTACHAAHGRHLLDHLIEVFGEELPLNLGQSDVLTPNITITTGQRPQTLGEIKPAMEHVEEQLTQLLATVHAGQESAEIDYDSKALFSGSLDHVGMEISDIVQIAALDFPKADPEAPLIEMGMGTIDKDKPFLCVIGHNVGGVTYMMDYMEEHELTDKVELGGLCCTAIDLTRYKEADRRPPYTKVVGSMSKELKIIRSGMPDVIVVDEQCVRGDIVPEAQKLKIPVIASNAKIMYGLPNRTDAGVEETIEELKSGAIPGAVILDYEKLGEISVRLAQEMHPIREAAGVREIPSDEQLKEWVDKCADCGACYLACPIELDIPEAMKFAKQGDFSYLEDLHDACIGCRRCEQVCKKEIPILSVIEKASQKIIAEEKGWMRAGRGQVSDAEIRAEGLNLVMGTTPGIIAIIGCPNYSDCAKAVYYIAEEFLKRNYIVVGTGCGSMDMGMYKDEDGKTLYERFPGGFQSGGLVNIGSCVSNAHITGAAQKVAGIFGGRTMEGNLAEIADYVLNRVGACGLAWGAFSQKASSIGTGCNIYGIPAVLGAHSSKYRRALIAKNYDESKWKVYDARNGEEMPIPPAPEFLLTTAETWQEAIPMMAKACLRPSDNSLGRSIKLTHWMELHDKYIGGLPEDWWKFIRTEADLPLAKRADLMKKLEAERGWEIDWKKKKIISGPKIKFDVSAQPTNLKRLCKGA
What is the function of this protein?
Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit alpha 1, ACDS complex subunit alpha 1, ACDS complex carbon monoxide dehydrogenase subunit alpha 1, ACDS CODH subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: SIX4_MESMA
Sequence: DGYIRGSNGCKISCLWGNEGCNKECKGFGAYYGYCWTWGLACWCEGLPDDKTWKSESNTCGRKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active only on insects (By similarity).
What are the official names of this protein?
Beta-insect depressant toxin BmKIT4, BmK IT4, Insect toxin 4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_XANC5
Sequence: MARIAGVNLPAQKHVWVGLQSIYGIGRTRSKKLCESAGVTSTTKIRDLSEPEIERLRAEVGKYVVEGDLRREIGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DGCQ_ECO57
Sequence: MQHETKMENQSWLKKLARRLGPGHIVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRDAVTEFEQHRDEHAWQIELNRRRTLSVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNA
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.  Involved in the regulation of cellulose production (By similarity).
What are the official names of this protein?
Probable diguanylate cyclase DgcQ, DGC, Cellulose synthesis regulatory protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_ECOSM
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ATPA1_CHLL3
Sequence: MQEKTLTESIDAALSSIGEASRTTQPEIELRENGVVTTVLNGIALIRGLPGVGYEELVEMSGGVYGIAFNVDPDEVGVVLLGEYAKLQAGGRARRTGRVMDVPVGDGLLGRVVNPLGRPLDAEGEPRFSGRLPIERPSPGIMDRNAVSTPLQTGLKVVDAIVPIGRGQRELILGDRQTGKTAIAVATILNQKGRNVICIYCAIGQRASAVAKVLAQLREHGAMAHTVAVVTEGNDPSGLQYIAPYAATSIGEYFMEQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYVHSRLLERSTHLRKELGGGSLTALPIIETEAQNISAYIPTNLISITDGQIYLSPTLFELGNLPAVDIGKSVSRVGGKAQLAAYRSVTGRLKLAYAQFEELENFARFGTRLDEASRKAITHGERIRECLKQDELDVLGVEEQILILLSLSEGQFDPLELSEVSGAMKRLSAAARELPRDLLERLHSDRPLSDEDRRRLLQTAEAALQKKRTAGRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYR_METHJ
Sequence: MYRTTCDAIAAILRQHTGKEDVMLTDGGDHADVASTIAFSLAKELRKAPAIIAQEIAGAISDQVMAETGAETRAVGPYVNFIFGAEYCMNVLEQAVREGYGKGQEKSERVVLEHTSANPNGPLHVGHIRNTIIGDTLARCFRKAGYPLEVQYYVNDMGRQIAIVAWGIATQGADIHAEGKGDHLIADVYIEANRHLEKEPALNAEIDRLMQLVESGDPDTISQFKIPVKRCLDGFKDTLAAMHVKHDRFIYESDFIRNGDTAKVLSRISHLPEARIEETLSLDLSAFGFEKNYILRRSDGTSVYAARDIAFHIWKGHNFDRVIDVLGADHKLIGTQLQATLEILGERVPEIVFFEFVSLPEGSMSTRKGKFISADELIAETERRAMEEVTARRSELSEEERKKIAHSVAISAIRYDIIRTIPEKSTVFDWKEALDFEKQSGPYIQYAHARACSILEKAESYTPCFEAEGEGEIALTKQIALFPKVITEVVTELKPHLLAIYARELADIFNSFYHAEPVLRAEGKIRDRRLTLVDATRNTLKEALETLGIDALRAM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_FINM2
Sequence: MFAIIKTGGKQYKVSEGDIIKVEKIEAEAGDKIEFDQVLMVAGDDVKVGSPVVEGAKVSAEVLDQKKDKKIVIFKFKAKKNYRKKKGHRQPYTLVKIEKIDA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: QUEA_VIBPA
Sequence: MQVSDFHFDLPDELIARYPQPERTASRLLQMDGNTGELIDGTFTDVLNQVQAGDLVVFNNTRVIPARMFGRKESGGKLEVLVERMLDEKSILAHVRCSKSPKPGTTIIVGENDEYSAEMVARHDALFELKFNSDKTVLDILEEIGHMPLPPYIDRPDEDADKERYQTVYNQKPGAVAAPTAGLHFDDVLLDKIKAKGAEFAYVTLHVGAGTFQPVKVDNINDHHMHAEYVEVPQEVVDAINATKARGGRIIAVGTTSVRSLESAAQDALKKGTELVPFFGDTEIFIYPGYEYQLVDCLITNFHLPESTLIMLVSAFAGYENTMNAYKHAVENKYRFFSYGDSMFIKKKTI
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP25_ARTBC
Sequence: MSGIALQGIRCHACRNAAFRSFAAISGLSSSIRRPQSSISYPGSKLYQRNVRTTGRRQFSTLGSVKSQVDSDLPTKTETKEDASAESSHIPWYLQDESHKPSSHPLKQQELPPLPENPPPILENLLQYISVDAGLDDLALLDLRGLDPPPALGANLIMIIGTARSVKHLNVSGDRLCRWLRSNYQLRPIADGLLGRNELKIKLRRRARKAKATGDASSLNSRDDGITTGWICVNVGDVENGPLKTKNSQDRNFIGFGGTEDKVRIVVQMLVEEKRSELQLEALWGSLLNPEAGEMNPAPRDDIWGNLSSETTSSRKGVDSIASTFSQRFPGRRHIHTQARPDTLEPLSHEILGNIVQESRPALPSKIVSTSMASPSVSSLLEQLSQLPEEEARRELGLGPGDRDSTLFLRLFYEAVSKSDTETVLIDKLSFARAAVLLKHPAYSKTDLYRAFKSMAASGCDISEELAMDTVRTLLSFQGPENAANERVPEQDIDLALRVLEHMSLRGIKIFNGEVFFLLHKASAFQSHVLPANDAPGATNTPADPDSISKVPVEELDHITTVHNRLSKLMASANVDFDYKDYPELLKMYFEHGNYSNFWRLWHRIPLMQIPRTKELYLLMFRLHAKLGHQRQAVDCLSSWVPMMAREQPPVALDEELTRDIMACMLVADPAIDQKTDDGTVSQFTRLWKQCLRDLKSFKAANSQ
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BIOB_CHLP8
Sequence: MSSRLHPDIERAYRVLETGEPVSLELASALGRLPESEVLDLVSLANKVKNLYAPGEGGGVHACSIMNAKSGVCGENCRFCAQSKHNSAEVDVYGLVDEAKVLDQARALHEQGVGHFGIVTSGYGYRKVTPEFERILGMIDLLHRELPDLKVCASLGMLGDEPAAELARHGIAHYNINIQVDPGRYGELIADTHSVDERIDTIRRLRAHGIAVCCGGIIGTGETMQERIGMIFALQKLDVTVIPLNVLVPIDGTPLEGAAPVSVPEIAKTFAICRLAHPSKIIKFAAGRETVMKDFQGLLMLAGANGFLTGGYLTTRGRDMEADRQLAGQIARFS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: GLPK_BACC0
Sequence: MKKYILSLDQGTTSSRAILFNKKGEIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETAVVWDKTTGKPIYNAIVWQSRQTAEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGGKAHVTDYSNASRTLMFNIHDLQWDDELLDMLTVPKSMLPEVRPSSEVYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGMRMFKDASESEVYASRVESTDGVYVVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELKTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKEQWHMDKRFEPTMEAETSEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y690_STAAT
Sequence: MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
What are the official names of this protein?
Probable transcriptional regulatory protein USA300HOU_0690.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS12_CHAGB
Sequence: MNPVLTSRQADELHKSIVAYLTANNLSTTAATLREELSLGEDVFDAEKTAKYQSLLEKKWTSVVRLQKKVMDLESRSVALQSELEHSTPASLSKRKDPTSWLPRSPPRHSLESHQAIVNCLAFHPVFSSLASGSDDSTVKIWDWELGELERTLKGHTRAVLDIDFGGPRGAILLASCSSDSTIKLWDPADEYKNTRTLTGHDHSVSAVRFVTSRPRSENLLVSASGDKTLKVWDITAGYCIKTLQGHTGWVRDVVPSLDGRFLLSSGTDQTARLWDISAADPESKLVMVGHENGIRCCAFAPPASYVHMAALAGLKKPPPSTSTAEFMATGSRDKTIKLWNSTGTCIKTLVGHDNWVSGLVFHPGGKYLLSVADDKTLRCWDLGDDGRCVKVLADAHGQFITCLRWAPGIVKKGADQGAEDTGPLEKTAPSEVQIRCLVATTSVDKVVRIFAD
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1-2, Lissencephaly-1 homolog 2, LIS-1 2, nudF homolog 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: MOMT3_SOLHA
Sequence: MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLKAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGIVHTSYNLTPLSQSLISDKDGSSIAPFLLLATDPVAVNSWFHFKDAILEGEIPFNKAHGVHAFEYHGKDSRMNGLFNRAMQNVTCTEMKRIVECYNGFQGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMFKSVPQRELILLKAILHDWDDEYCVKILKNCWRALPKDGKVVVIEQMQPEYPETNLISKNSSSVDMLMMTMLDGGKERTKQQFEDLAKQAGFTVFKIVARAYYCWVIELYK
What is the function of this protein?
Flavonoid 3-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as myricetin derivatives, aroma compounds possessing antioxidant properties and exhibiting pharmacological activities such as anti-carcinogen, anti-viral, anti-thrombotic, anti-diabetic, anti-atherosclerotic, and anti-inflammatory effects (PubMed:22711283).  Catalyzes S-adenosylmethionine-dependent regioselective 3-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates (PubMed:22711283).  Active with myricetin, quercetin, kaempferol, 4'-methyl kaempferol (kaempferide), 3'-methyl quercetin (isorhamnetin), 7-methyl quercetin (rhamnetin), 3'-methyl myricetin (laricitrin) and 3',5'-dimethyl myricetin (syringetin), thus producing 3-methyl myricetin, 3-methyl quercetin, 3-methyl kaempferol, 4',3-methyl kaempferol, 3',3-methyl quercetin, 7,3-dimethyl quercetin, 3',3-dimethyl myricetin and 3',5',3-dimethyl myricetin, respectively (PubMed:22711283).  Inactive with flavonol substrates methylated at the 3-hydroxyl position such as 3-O-methyl quercetin (PubMed:22711283).
What are the official names of this protein?
Myricetin 3-O-methyltransferase 3, ShMOMT3, 3',5'-dimethyl myricetin 3-O-methyltransferase, Syringetin 3-O-methyltransferase, 3'-methyl myricetin 3-O-methyltransferase, Laricitrin 3-O-methyltransferase, 3'-methyl quercetin 3-O-methyltransferase, Isorhamnetin 3-O-methyltransferase, 4'-methyl kaempferol 3-O-methyltransferase, Kaempferide 3-O-methyltransferase, 7-methyl quercetin 3-O-methyltransferase, Rhamnetin 3-O-methyltransferase, Kaempferol 3-O-methyltransferase, Quercetin 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: OBG_CHLP8
Sequence: MKFVDSAKISVKAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVYLRANRQLSTLLDFKYRKSYIAGRGEHGMGARKSGKNGNDVVIGVPCGTVVRNAETGEVLCDMVEDGQEIMIAKGGRGGQGNQHFATATRQAPRFAQPGEKGDEIELEMELKLMADVGLVGFPNAGKSTLISVFSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGIQFLRHIQRTKTLLVMVPSDSADIAAEYATLLRELEKFDASLLSKPRLAVITKMDIAPEDFAIPELEPGIKVIAISSVAGQGLKALKDELWRQISTSTQITVDDAGN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_DICDI
Sequence: MSTLGLLIMLLGIIIMCTLVILRSVNPIYSILNLIVIYGCYASILLTVEMEFLACIYILVNVGAIAVLFLFIVMMININIVEIQETMKKYNIYMIVGIIGVVGLLGILITNYQIRIKEEVIADFSMFLINSEVVQLQATPSYLDFYSLFVETTDIRTMGSNVIYGSYSIWFIMACIILLIGMVGVIYITEDLIIEKRTLNERRRQDINSQVLREYKITIRNYRESK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RISB_ZYMMO
Sequence: MAKFLIVEARFYSHLNDMLIQGAKQAIEEAGHECEVITVPGALEIPAAITMASDTGLYDAFVALGVVIRGETYHFEIVASESARGVMALTLDGLVIGNGILTVENEQQALVRADPQQKNKGGDAAKAAITMFNLKKKLS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HIP10_ARATH
Sequence: MQETVVFEWGSFDVRTKEKAMKVVCEFPGVTVIDVKERGKLKVTGQFDKFIMTKKLKKICDYVDITAVGPEGQPAQNRNPVKKPEPKVIRGRPYPPQKKTPGKNSDECIIL
What is the function of this protein?
Probable heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 10, AtHIP10.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: KAD_CORK4
Sequence: MRLVLLGPPGAGKGTQAAILSDKLGVPHVSTGDLFRENIGNNTELGQEAKSYIDAGKLVPTSVTVNMVKDRLSQDDAADGFLLDGFPRTVEQGDELKNILDGLGTKLDAVLQFDVSEDVVVERMLARGRADDTEEVIRTRLKVYRDETAPLLEYYKDSIIRIVAEGSVEDINERTMEALKALDS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.