PharMolix/UniProtQA huggingface dataset:
Protein: RL21_SHEPC
Sequence: MYAVFQSGGKQHRVAEGHTVRLEKLEVATGSTVEFDQVLLIADGETVHVGAPLVAGGKVVAEVVSHGRGEKVTIVKFRRRKHHDKKMGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: METK_METRJ
Sequence: MPRSNYLFTSESVSEGHPDKVCDRISDTVVDAYLAAMPEARLGVETLATTNRIVIAGEVRGPDSVTFKDLEALTREAVKDIGYEQSGFHWKNNDVAIHLHAQSADIAQGVDAAGNKDEGAGDQGIMFGYAADETPELMPAPIFYAHKILKDLADARKARQGDAAKLGPDAKSQVTVRYENGRPVEVTQIVLSTQHLDESLDSADVRAIVEPYILKALPQGWVNEGTVWHVNPTGKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLASRATIQLAYAIGVSKPLSIYVDLHGTGTVDEAKLEAVLMDAMDLSPRGIRTALSLNKPIYARTSAYGHFGRAPEADGGFSWERTDLAGKLKSALA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_BACVZ
Sequence: MAEQKKVVLAYSGGLDTSVAIKWLQEQGYDVVACCLDVGEGKDLAFVQQKALEVGAVNSYVIDAKEEFAREYALISMQAHTMYEGKYPLVSALSRPLIAKKLVEVAEKENAVAVAHGCTGKGNDQVRFEVSIKSLNPDLEVIAPVREWQWSREEEIEYAASRGIPIPINLDSPYSIDQNLWGRANECGILEDPWAAPPEGAYDLTASLENTPDVPEIIEIAFEAGVPVSIDGVTYPLADLILKLNETAGKHGIGRIDHVENRLVGIKSREVYECPGAMTLITAHKELEDLTLVKEVAHFKPAIEQKLSEIIYNGLWFSPLKDALLAFLKETQKHVTGVVRVKLFKGHAIVEGRKSEYSLYDEKLATYTKDDAFDHHAAIGFIELWGLPTKVNSIVKKKEQIEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHE2_ORYSJ
Sequence: MNALAATSRNFRQAARLLGLDSKLEKSLLIPFREIKVECTIPKDDGTLASFIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVAAIPYGGAKGGIGCAPGELSTSELERLTRVFTQKIHDLIGAHTDVPAPDMGTNSQTMAWILDEYSKFHGHSPAVVTGKPIDLGGSLGRDAATGRGVMYATEALLAEHGKSISGSTFVIQGFGNVGSWAARIIHEKGGKVIALGDVTGSIRNKNGLDIPALMKHRNEGGALKDFHDAEVMDSSELLVHECDVLIPCALGGVLNRENAPDVKAKFIIEAANHPTDPEADEILAKKGVTILPDIYANSGGVIVSYFEWVQNIQGFMWDEEKVNMELHKYMNNSFQHIKAMCKSHDCNLRMGAFTLGVNRVARATLLRGWEA
What are the official names of this protein?
Glutamate dehydrogenase 2, mitochondrial, OsGDH2.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS13_BURM1
Sequence: MARIAGVNIPNHQHTEIGLTAIFGIGRTRSRSICVAAGVDFSKKVKDLTDADLEKLREEVGKFVVEGDLRREVTMNIKRLMDLGCYRGVRHRKGLPMRGQRTRTNARTRKGPRRAAQALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YQGF_AMOA5
Sequence: MGRIMAIDYGLKRVGLSVTDPLQIIASPLTTVAANDTLTFLQTYVKKENVEAFVVGYPTDIKDKNTPIIVAISQFIELLQRNFPDQQIFQHDERYTSKLAAASLVEGGFKKKDRRNKENLDKLSATIILQSFLSSYKRHYI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_SPHAL
Sequence: MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVAYRARFWGVGMGLLRADPAAVAFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLVGGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMIPGVSRSGATIMGALLMGVERRTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIVGRFGFAPFAWYRIIVGGGALLWLAWK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGB_RHORT
Sequence: MDPKAYSEAVAALVGARHSNPFAFLGPHEGRAEGGRGGFCIRCFRPKATAVSLISAADDTVLGRMKRLHPDGLFGIDLPEAPGALAYRLRVSEGDEDRDIEDPYRFGPVLGELDRHLLGEGTHLDIYRKMGAHPMTRDGVRGTGFALWAPNATRVSVIGDFNGWDGRLHPMRAHPGSGVWDIFLPGVVEGHLYKYELLGPDGSLLPAKADPYAFQAEKPPHTASVVRGLGTYAWNDGRWMSERADRVATSAPVSIYEVHLGSWRHGGGDRSLSYREMAEQLIPYVKEMGFTHIELLPVSEFPFDGSWGYQPIGLFAPTSRFGEPDDFRHFVDRCHQEGVGVILDWVAGHFPEDAHGLSWFDGTHLYEHSDPRQGRHMDWGTYIFNYGRNEVRNFLLANALFWLEQFHIDGLRVDAVASMLYLDYSRKAGEWVPNKFGGRENLEAIDFLRRMNELVYGRFPGAVTIAEESTAWPMVSRPVHLGGLGFGYKWNMGWMNDTLSYMSQDPIYRRFHQHDLSFGLLYAFTENFVLPLSHDEVVHGKRSILGRMPGDAWQQFANLRAYYGFMWTHPGKKLLFMGCEFAQGREWNHNASLDWHLLDIDWHKGVQALVRDLNGLYAGVPALHDRDTEGYGFSWIDCTDADQSVLAFLRFGETAEDVVMVVCNFTPNPRHGYRLGAPIAGRWREIFNTDSAHYGGSNMGNSVVETEETKSHGHAQSVVLTLPPLATIVLRPDGPITRIA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MIAA_CLOBL
Sequence: MIDLLIIAGPTAVGKTDISIKLAEKLNGEIISADSMQIYKYMDIGSAKITKDEMKGIPHHLIDVVEPHEEFNVSSFKALAEESIKDIWNRGKLPIIAGGTGLYINSLIYNYDFTDADRDEKYREYLTKLAEDKGKEYVHSLLKDIDEESYEKLYPNDLKRVVRALEVYKITGKSISEYTKENEKKLYDIPYNVNYFILNMNREVLYERINKRVDIMMGKGLIEEVKKLESMGYTPDMQSMKGIGYKEVLFYLNGDISLDEAIYLIKKGSRNYAKRQLTWFRKDKRSIWIDKDKYNSEEEIVDKIIKMVKDK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYA_HALMA
Sequence: MSDLDEAYQLDYFEEEGFHRQECVSCGDMFWSRVKRETCGEPPCAEYDFIDNPGFDESHSLTEMREAFLSFFEDRDHERIDPYPVAANRWRDDVLLTQASIYDFQPLVTSGTTPPPANPLCISQPCIRMQDIDNVGKTGRHTMAFEMMAHHAFNAREDIEDPEQYAYEGEVYWKNETVQYCDELFEEMGANLDEIVYIEDPWVGGGNAGPAIEVIYRGAELATLVFMSMEQDSDGEYEMKDGNRYSPMDTYIVDTGYGLERWTWMSQGTPTVYEAVYPDMIAFLKDNAGIELTDEEERIVHEAAKLAGRMDIDEAEDIEAERDTIAAEVGVEVEEMRDLMAPLEDIYAIADHCRTLAYMLGDGIVPSNVGTGYLARMVLRRTKRLVDGVGVDAPLDELVDMQAERLDYENRDTIRDIVRTEVEKYRETLDRGGRRVRQLADEYAEKGEPIPTSELVELYDSHGIQPDMVEEIAAEKGVAVDVPDDFYAVVAQRHGGDDTATEESQTPYEDRLEELPETDRLYYEDQQRTEFEAVVLEVFDRDEDTYDVVLDQTMFYPEGGGQPPDKGTLSTDDVSAEVTDVQQYGDVIVHTCDDDPGKGEFVRGQVDATRRQRLMQHHTATHIVIHSARQVLGEHVRQAGAQKGTDSARIDIRHYESVSREKVKEIERLANDIIQDNITVSQEWPDRNDAEERYGFDLYQGGIPAGEQIRLITVGDDVQACGGTHVARTGDIGAVKLLNTERIQDGVIRLTFAAGNAAIEATQRTEDALTEAADILDVAPDAVPETAERFFDEWKARGKEIEQLKEQLAEARASGGGDNEEVGVGDATAVVGRIDADMDELRAQANAIVEQGNIAVLGSGLDGAQFVVSVPDGVDVDAGEVVGELAGRVGGGGGGPPDFAQGGGPDADALDDALDDAPEILRTVANA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAT_PLAVS
Sequence: MDTHGEKMKNLEIKKHSRGDLLLLRSSDLHSFRKLQREVDKMGLLSSAEQHLSGILTTLENVADQDNTLYCLTQRGELIGMLKIGTKRLYLYNGKDLHCRSCACLLDFYIRRDFRKRGLGLELFNFMLRDKAISPSRLCYDNPSHKLRSFLKKHFSPCALIKQPNNFVIFAEYFGEPEAAPFER
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: MENE_SALTY
Sequence: MTFTDWPWRHWRQVRSQAPALRLNDEVLSWRALCERIDVLAGGFAAQGVREGDGVLLRAGNQPRTLLAWLALMQCGARVLPVNPQLPQTLLEALVPKLTLRFALTLEGENAFSGLTALQIQKSTAAYAVAWQPQRLVSMTLTSGSTGLPKAAVHTCQAHLASAQGVLSLMPFGPQDDWLLSLPLFHVSGQGIMWRWLFAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLANRAAVTLKAVLLGGAVIPVELTDQASKQGIRCWCGYGLTEFASTVCAKEADGSDDVGAPLPGREIRIVDNEVWLRAASMAEGYWRDGKLIPLVNDEGWFATRDRGELNHGRLTIAGRLDNLFFSGGEGIQPEEVERVINAHPLVQQAFVVPVEDKEFGHRPVAVVEYASQAGDVNLAEWVRDKLARFQQPVRWLTMPSELKNGGIKISRRALQQWVCENCKN
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: RBL_BRADU
Sequence: MNAHTGTVRGKERYRSGVMEYKRMGYWEPDYTPKDTDVIALFRVTPQEGVDPIEASAAVAGESSTATWTVVWTDRLTAAEKYRAKCHRVDPVPGTPGSYFAYIAYDLDLFEPGSIANLSASIIGNVFGFKPLKALRLEDMRFPVAYVKTFQGPATGIVVERERLDKFGRPLLGATVKPKLGLSGRNYGRVVYEALKGGLDFTKDDENINSQPFMHWRDRFLYCIEAVNRAQAASGEVKGTYLNITAGTMEDMYERAEFAKELGSCIVMIDLVIGYTAIQSMAKWARRNDMILHLHRAGHSTYTRQKSHGVSFRVIAKWMRLAGVDHIHAGTVVGKLEGDPNTTRGYYDVCREDFNPTKLEHGLFFDQSWASLNKMMPVASGGIHAGQMHQLLDLLGEDVVLQFGGGTIGHPMGIAAGAIANRVALEAMILARNEGRDYVHEGPEILAKAAQTCTPLKSALEVWKDVTFNYQSTDTPDFVPTALETV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: TRPR_SALNS
Sequence: MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLENVLLKNA
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYY_ANGJA
Sequence: MAVVLKPWTVLVALVLCLLVCLGTFVDAYPPKPENPGEDASPEEQAKYYTALRHYINLITRQRYGKRSSPEGVMSELLFGDNSEHNQRSRYDDSYMW
What are the official names of this protein?
Peptide YY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACHA2_RAT
Sequence: MTLSHSALQFWTHLYLWCLLLVPAVLTQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNVTSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPDLKLSPSYHWLETNMDAGEREETEEEEEEEDENICVCAGLPDSSMGVLYGHGGLHLRAMEPETKTPSQASEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-2/CHRNA2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: DF188_ARATH
Sequence: MKNSSLLFILIVVFVISSSENGIMIGEAKKCSNSWICEGDEKCKEKCMADYKGNGTCYYPSPPSKQHPEFFYPTCWCGFDC
What are the official names of this protein?
Putative defensin-like protein 188, Putative low-molecular-weight cysteine-rich protein 41, Protein LCR41.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCD_SALPA
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RL4_AMOA5
Sequence: MELSVLQYTGKDTGRKVVLSDTIFGITPNDHAIYLDVKNILANKRQGTHKSKERGEIAGSTKKIKKQKGTGTARAGSIKSPIFRGGGRVFGPKPRDYGFKLNKKLKKLARKSALTYKAQQGNISVLEDFSFEMPKTKMYLEMLQNLNMADQKTLLILPAVDKNLVLASRNLPNTSVALVEQINTYDLLYSKKILISETALSKLTENFNNA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MYL3_MOUSE
Sequence: MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 3, Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB.
Protein: Y3020_BORBU
Sequence: MNKKFSISLLSTILAFLLVLGCDLSSNNAENKMDDIFNLEKKYMDNSNYKCLSKNEAIVKNSKIKLGVNNTRSRSYSSRETNVSDSYNKTYSYCKSN
What are the official names of this protein?
Uncharacterized lipoprotein BBF20.
What is the protein family that this protein belongs to?
To B.burgdorferi BBD15.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y927_BACP2
Sequence: MNIFTTFLFMIVIGAVIGAATNHLAIKMLFRPYKPYYLFGKQLPFTPGLIPKRRDEVAKQVGVLVMEHLLTPEGIQKRFESSEAKQEILHTVHRLIDKGADMEITVLSLLERFGVSHADVKADEWLHHWSDRKLASLLKKYNEQTLSELLPLEVENKISSKIPDAADYILKRGIHYFESEEGKARLGNMIDDFLKERGMLGGMVQMFLGNSSLIDRVHPEIIKFLRNAETKKFLTDLLVQEWEKVKQFSLQELDDKWNVKELAYSVKKQLLSHFSTKVILDKPVGSYVSEVAVDLKIYLAPVLVDKGIKAASNALEGLLAKLKFEDIIREQIELFPLKKMEELVISISNNELKMITFLGGFLGGLIGAIQAIFVTLF
What are the official names of this protein?
UPF0754 membrane protein BPUM_0927.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1278_ARATH
Sequence: MPTEDRVCFTWEEYARHVREYWRGVAESDGFDSEDIRSPVVLTGLFHYDCQSGRHYPEPLLGTSFELAALLKFNKTMNLTSSYYITLLAHDPSLEKTFQVRVDEREYGSLDLTVAIARPKKDQNEVSDGVFQGPLPDWPSEDALRHDRNRFYELEISEWQATDWISLYLKLLILATDRGMFVQTGLPQVQILEVVIETEEENEKPPDKRLNARRAHVYITFTGLPKSPRLVEIGEHVERKAIIRRVIDASGYLTLLGKFWSGKDTDQQRSMTLPSGEQAESSKKRPRLS
What are the official names of this protein?
UPF0725 protein At1g27860.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: RS17E_HALSA
Sequence: MAIKPDYVKKTGNILMERYQDAFSREDFEHNKDAVTELTNIESKNVRNRIAGYITHKRN
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: RPOC1_NOSCO
Sequence: MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPKDWECHCGKYKESVIEVLSVSAVVLEVTESRVRRHRMGYIKLAAPVAHVGYSKAFLAIFHSVGYALRDVEQIVYFNSYVVLSPGNAETLTYKQLLSEDQWLEIEDQIYSEDSLLQGVEVGIGAEALLRLLADINLEQEAESLREEIGNAKGQKRAKLIKRLRVIDNFIATGSKPEWMVMAVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVIHQAAPMISRNDPSVWDVLEEVIEGHPVMLNRAPTLHRLGIQSFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLSLESQAEARLLMLASNNILSPATGKPIITPSQDMVLGAYYLTAENPGATKGAGKYFSSLEDVIMAFQQEQIDLHAYIYVRFDGEIESDQPDTEPVKVTENEDGTRTLLYKFRRVRQDAKGNVLSQYIYTTPGRVIYNNAIQEALAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: HRCA_BACVZ
Sequence: MLTNRQLLILQVIINDFIQSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRYYVDHLLSPVKLTKTDLDLIHSIFKEKIFELEKTVQKSAQILSDLTNYTSIVLGPTLSENYLKQIQIVPIQPDKAVAILVTNTGHVENRTINFPAKVDLADIEKLVNILNDRLAGVPMDELNERIFKEVVTYLRQHIANYDSILESLRSTFHPAAHVEKLFFGGKINMLNQPEFHDIERVRSLLSLIEKEQDVLKLFQSSKAGISIKIGKENDYEEMENCSLITATYTVDTKQIGSIAIIGPTRMNYSRVVSLLQHVTSDLSKAFTSLYDE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL18_ECOUT
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: OCRL_RAT
Sequence: MEPRLPIGAQPLACLHMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLAAQEAQSQLLVPEQKDSSNWYQKLDTKDKPAYSGLLGFEDNFSSMNLDKKMNTQNPPTGIHREPPPPPSSNRMLPREKEALNKEQPKVTNTMRKLFAPNSQSGQREGLIKHILAKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWAMAVERGLPSKAKYKKVQLVRLVGMMLLVFAKKDQCQYIRDIATETVGTGIMGKMGNKGGVAMRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMSFSVPNQTLPQVNIMKHDVVIWLGDLNYRLCMPDANEVKSLINKNELQKLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLDLSRREFMFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDTQYCKPWLRAEPFEGYLEPNETIDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNVSTNMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLVFLLGSEED
What is the function of this protein?
Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2.  Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate.  Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes.  Involved in primary cilia assembly.  Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling.
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase OCRL, Inositol polyphosphate 5-phosphatase OCRL-1, OCRL-1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Membrane, clathrin-coated pit. Cell projection, cilium, photoreceptor outer segment. Cell projection, cilium. Golgi apparatus, trans-Golgi network. Endosome. Cytoplasmic vesicle. Note=Also found on macropinosomes.
Protein: RL31_SHEB2
Sequence: MKPGIHPKYAIITANCTCGNVIKVNSTAGKDLHLDVCGACHPFYTGTQKVVDTGGRIDKFNKRFAVLAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SSRP_CAMC1
Sequence: MIKDLAKNKKALHDFSILETFEAGIVLKGSEVKALRAGRANLKDSFVRVIKGELFLLNAHISYLETTHSAFRPNERAARKLLMHRKQIDKIFGQVSQDGLALVVLALYLSDKNIVKARLALAKGKNLHDKRETLKRREADKEARAAIKRYV
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.