PharMolix/UniProtQA huggingface dataset:
Protein: METK1_HORVU
Sequence: MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRDIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGIMFGYATDETPELMPLTHMLATKLGARLTEVRKNGTCAWLRPDGKTQVTIEYLNEGGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPGKYLDENTIFHLNPSGRFVIGGPHGDAGLTARKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMITINLDLKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT52_CYRHA
Sequence: DPSGSPHIRILPQETFEDICRLPSDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type serine protease inhibitor HNTX-852.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYG_CLOAB
Sequence: MKDEKTMDKIVSLAKNRGFVFAGSEIYGGLANSWDYGPLGVELKNNVKKLWWKKFVQDNTYNVGLDCAILMNSEVWVASGHLGGFSDPLMDCKECKSRFRADKIVEDYLTEQGAEVASADGWSNEKLENFIKDKHIKCPKCGKENFTSIRKFNLMFKTFQGVTEDASSEIYLRPETAQGIFVNFKNVQRSSRKKVPFGIGQIGKAFRNEITPGNFTFRTREFEQMELEFFCKPGTDLEWFKYWKDYCWSFLLDLGINKENLRFRDHSAEELVFYSKATSDIEYKFPFGWGELWGVADRTDYDLKKHMDHSGEDMNYLDPSTNEKYVPYVIEPSLGADRVALAFLIDAYDEEELEGGDQRIVLHFHPQIAPIKAAVLPLSKKLSEKALDVYSKISSKFNIEYDETGSIGKRYRRQDEIGTPYCITVDFDTLEDEAVTIRDRDSMSQVRVKIEELEKYLEEKIK
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_PHEZH
Sequence: MHLYRTHTCGQLRASDTGSKVRLSGWVHRKRDHGGLIFIDLRDHYGLTQLVVSPSTPGFDLVEHVRAESVIRVDGEVVARSAETVNPNLPTGEIEVVVRQVEVLSEAAELPLPVFGEPEYPEDIRLKYRYLDLRRETLHRNIVLRSQVIQSIRRRMIDQGFLEFQTPILTASSPEGARDFLVPSRLHPTKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDLRADRSLEFYQLDVEMSFVTQDDVFAAIEPVMHGVFTEFGEGKPVTPYPFPRIPYREAIAKYGSDKPDLRNPIEMQDVSEHFRGGGFGLFARILEDAKNAVWAIPGPKGGSRAFCDRMNSWAQGEGQPGLGYIFWSDDQGGWGGPIAKNLGPEKTDGLMKALGLGQGDAAFFVAGDPKVFYKFAGAARTKVGTDLKLIDEGRFEFCWIVDFPMFEWSDEEKKYDFSHNPFSMPQGELDALLNKEPGEIVAYQYDIVCNGHELCSGAIRNHRPDVMLKAFEIAGYGPEVVEEQFGGMLNAFRHGAPPHGGLAPGIDRIVMLLAGETAIREVIAFPLNQQGQDLLMNAPSEVSEKQLKELHIRLAPPIKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKQ9_CAEEL
Sequence: MRLVEIGALSADSDLVLWEASCETISHQISLKLARKEGGLMEIFNSVVASLPRKSDSFRFSAISSKTSWESAHRNLLENLTKTVPVLLENGWKKSPDFQKNSLIDLFSLLEDEDATRIFKMTQESRSITEDDVEDYFSMFDKKFDRLLTYGAPQFENCVRDSPMRQKYANLCVEVLVAVGASVKNAQKITDFLEKQSMKVSKIWMTRIPEIFEKITNFYDYPMMFDVAMALDGFPLRKVFLARRFALQSILEVFIEMAPNTKYKVRERVRQELEKASRFVGYASEMGHDNLLSSFSPKIVSSIEDSKHILEVETIERLRRCGYLENLGAPLDELVRAQIASIREILPHFSAEFVHLALRHFSYDSEVTLASLLSRENLPLELLRLENVELRAGIGSGEWPPLDFTASDEIEKLARADKRAKDEETRKNNETKSASNLFSLAPILSDRPPSPPVDQQAELRAHAEAYRTSVLTKLQKIRADAAGPSSPSEKIAVDAENLVPLATSKKYSALNSLKISEADKVAIRPTYNKYRYETPNDGGNGVYDDEYDDEFDGREFNIERLNQELETSSEEDEAGSSAPPGLSQPPPYQGSRGGRGGRGARGGNRGGAPSADGYTGGHDRQMKEKHKSDIKQRGADRKKRGVY
What are the official names of this protein?
Uncharacterized protein C06E1.9.
Protein: RLME_SALSV
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_STRPI
Sequence: MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVLPETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RUVA_ELUMP
Sequence: MIGYLKGQILSLSEDSVLILVNGVGYEVNCAPVAVSALEEGQETALYIAESISPYDGTVLYGFLTKEDKQLWAIFKTSIPNTGAKKALEYLNKALRSVADFHNAIVKKDPKILTGIFGFTAKTAEKLIHSLDGKMDAVTIAGVPKIKIEGEAPFMSEVMMALTALGYSPMEARKAIDQLYKTGLANDSVENIIRAALRILKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EX7S_BRUME
Sequence: MTEPSNADIAVMSFEDALKQLEKIVDDLERGDVPLEESIRIYERGEALKKHCDTLLKSAEDKVEKIRIGRDGQPVGTEPLDPE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CLOK1
Sequence: MRIGEISRKTYETDIEVKIDLDGRGKYNIDTGIGFFNHMLCMIAKHGIMDMDVYAKGDLDVDFHHTVEDVGICIGKSIKKALGNKKSIKRYGTFFIPMDESLSMCSVDLSGRPFLVFQGELKNSKVGEMDTELIEEFFRALAFNAEMTLHIKVFYGKNTHHIIESVFKSFAHALREAVSIDEKIEGTMSTKGMI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGKE_MOUSE
Sequence: MEGDQRSGPPAQSLLPDGHLVLWTLCSVLLPVFITLWCSLQRSRRQLHRRDIFRKSKHCWRDTDLFSHPTYCCVCAQHILQGAFCDCCGLRVDEGCLKKVDKRFPCKEIMLKNDKAADAMPHHWIRGNVPLCSYCVFCRQQCGSQPKLCDYRCIWCQKTVHDECMRGSLRSEKCDFGEFRNLIIPPSYLTSINQMRKDKNTNYEGLASKFGKQWTPLIILANSRSGTNMGEGLLGEFKILLNPVQVFDVTKTPPIKALQLCTLLPYYSVRVLVCGGDGTVGWVLDAIDEMKIKGQEKYIPEVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKIELELDGERVELPNLEGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEIVGVYGSFHCAQIQVKLANPFRIGQAHTVRLTLKCSMMPMQVDGEPWAQGPCTVTITHKTHALMLYFSGEQSDDDISSPSDHEDVKEAE
What is the function of this protein?
Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:11287665).  Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:11287665).  Also plays an important role in the biosynthesis of complex lipids (By similarity).  Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle (PubMed:11287665, PubMed:19744926).  Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently (By similarity).
What are the official names of this protein?
Diacylglycerol kinase epsilon, DAG kinase epsilon, Diglyceride kinase epsilon, DGK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Cytoplasm.
Protein: GLYA_ANADE
Sequence: MMPTQRLAEADPQIAKLIREETRRQAEGLELIASENFVSPAVLEALGSTLTNKYAEGYPGKRYYGGCEVVDQVEQLAIDRAKQLFGADHANVQPHAGSQANMAAYFALAKPGDTVLAMSLNFGGHLTHGSPVNFSGKLFKIVPYGLRQSDETIDMDEVARLAREHRPRILMVGASAYSRTLHFDRFAEIANEVGAAMVVDMAHIAGLVAAGLHPSPVPHSEIVTTTTHKTLRGPRGGMILCREAHAKTLNSQIFPGIQGGPLEHVIAAKAVAFGEALRPEFKEYQRRIVENAQVLAEGLKSAGLRLVSGGTDNHLMLVDLRPKKLTGKVAEEALGKAGITVNKNMIPWDPEKPMTTSGIRVGTPALSTRGMGPREMTLVAALIGRVLDAPADEQVLARVRGEVKDLCAHFPMYADRV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_BACMK
Sequence: MLNIGQFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEILTFAVRRMDIFDAKQPNLLEKLDVKKYTLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLKASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATVPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGANDPIKMAYAMKLGIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NM111_YARLI
Sequence: MVPQKRSRDDLNGLKSPVRSPKKIAMPAATSASNGVVAGWHSTIEKVVKSVVSIQFAQVASFDCESAVVSEATGFVVDTEMGIIMTNRHVVGAGPFCGYAVFDNHEECELVPIYRDPVHDFGFLKFDPSKIKYMNVQKLRLCPEKAQVGTEIRVVGNDNGEKLSILSGFISRLDRNAPDYGDLTYNDFNTEYIQAAASASGGSSGSPVVDIDGDAIALQAGGSTDASTDFFLPLNRGKRALECILRGDKVTRGTIQTHWMLKPFDECRRLGLSASNEKKQRELFPSTIGMLVAETVLPEGPSAVAATEGDILLSVNSTPISSFITLDSILDEAVGDIVKVTVERNGAEITFDIYVQDLHSITPDRYVEVCGASFQDLSYQLARIYAIPVRGVYVSEVGGSFRLDGQGNESKGWVVDSIDDIDTPDLDTFIKVIAAIPDGRRVSIRYRHLRDLHTTNFTITYIDRKWHSSFRLAVRNDTTGKWDFTDLSKQYPVPKKDEIVPQRATFTDPNLEEADAACAPLSRSFVRVSCMIPYKIDGFPRTMRQSHGLVVDAEKGLVLVSRSIIPYDLCNVSVTFAESVVVPGTVVFMHPLQNYAILQYDPKLVHADIETAKLSSTPLKQGDPVLFMGHNLSLRLVTTRTKVSDVTAITIPPNAGEPYYRALNLDAITVDSTIPNGCTAGVLADPKTGVVRAFWLSCMGERTEGRQHEYRLGIDTSTFLETVQRIRAGKPPQERFLDVEIASVSMIQARIRGVSPEWIAAVEQDNSQRHQLFEVIRTATPINGNSQALKEGDILLSINGKLLTTLTTLSEAGDKEQVTIKLVRNKKEEEIQAPTTDSAFETSQAVFWCGAVLQTPHHAVRQQIKKIHSGVYVSSRAQGSPAYQYLIAPTNFITHVNGTATPDLETFLSVVTKIPDNTYVKLRIVTFDNVAFACSMKMNYHYFPTAEIKKEGNEWVGYSYKDGKRVKESDENVEEQVNEAEKQE
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease NMA111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_XANCB
Sequence: MNSSFSAPAKKSLGQHFLADRYYIDRIVQAVDPRPGQHLVEIGPGQGAITFPLLRKHGALTVIEFDRDLIAPLTDAAAPIGQLQIIHRDVLAVDFTAVADGTPIRLVGNLPYNISSPILFHALDHASAVADMHFMLQKEVVDRMAAGPGSKVYGRLSVMLQAYCEVTALFVVPPGAFRPPPKVDSAVVRLVPRDAASVLIKDRKRFADVVRAGFGQRRKTLRNALSTVCEPAHFEAAGVRPDARAEQLEVADFIRLANVELA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ACICJ
Sequence: MAARVIDGKAVAAALRAEVAARAATLPYAPGLAVVLVGEDPASQVYVRNKERAAKAAGFASETIRLPASASQAELLALIARLNHDPAVDGILVQLPLPAGIDPQAVIRAIDPAKDVDGFHPDNVAALALGTPFLVPCTPRGVMKLLAAAGIAPRGARALVLGRSNIVGRPMAALLLAADATVTIAHSRTRDLAAECRRAEILIAAVGRAEMVRGDWVSPGATVIDVGINRTAAGGLVGDVAYAEAAAVAGAITPVPGGVGPMTIACLLENTLIAAAARR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EFTU_COLOB
Sequence: MERLLHMTFRNKKIHLNVGTIGHFSHGKTTLTAAITAVLAGIGYTQPKQNDAIDSTSEEKARNMSIYVHHVEYETAARHYSHLDCPGHVNYINNMITGVSQMDGAILVVSAVDGPMAQTKEHILLAKLLGISSILVFINKEDELDDQEVLPMLIQNMRQILIYYGFPGHTSPILCGSALLALEAMNENPNFNRGKNKWVDKISSLIDHLDLYLPTPRRKLNKPFLMPIERVILIPSFGLVGTGTIEKGHINIGESVEIVGFKDTQHSKVISLKMFNKTLEQAIAGDDIGIFLEGTNKNNFQKGMVIAKPNTIQSWNHFEAQIYILRREEGGRRSPFFQGYCPQFYFRTIQITGRMESFEYEIGGKTWMVMPGEKIKAIIQLIFPIALKKKMRFVIREGGFTIGVGIILELIKIKN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL25_DESAP
Sequence: MAVVDLKARPRAGRGKGYRNRLKQNGLIPAVIYGKEVGSLLLEVETRAVQDILTKTGRNALIQLRVEPEKGRAKKYDAIIKDVHMHPYKNEFFHVDFHQISLKDELTTSVNLKLTGSAPGVTAGGRLEQLIRQVEVSCLPRNIPDHIEVDVSGLGIGDAIHVSDLKAPEGVKFETDGDVTVVTLIAPHREEEKAPEETGEAAPAPTPETGQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: DAPE_MAGSA
Sequence: MSFRDPVPLAQALIRCPSVTPEDAGALDVLAGALEELGFACHHIRSATGGPEIRNLYARLGTEAPNLCFAGHTDVVPPGKGWTVEPFAAGIDQGRLFGRGSADMKGAIACFVAAVARLLEDGAPKGSLSLLITGDEEGPAVDGTVKVLDWLAARGERIDCCIVGEPTNPRKLGDMMKIGRRGSLNCRLTVFGTQGHSAYPHLADNPIPRLLDILRRLTEAPLDEGTPHFQASTLALTTVDVGNPATNVIPAEARAGFNIRFNDLHSGASLERWIRDTVAQAGGEVEIKVEVSGESFLTPPGALSDALAEAAFEVTGLRPELSTSGGTSDARFIKNHCPVVEFGLVGQTMHKSDEHVSVADMEALTEIYRRVLVRLAAPS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YAJQ_ECO81
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGSDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: EXBB_XANCP
Sequence: MLQEFVIAAAAGGSNPSAALSQMGFEHLITEMTSSPGDFAVSWVVLITLIAMSAASWYWTVINIFRATRLKSAADRVTTAFWDAPNAQDAIRAMEEQPASEPFSKIALDAAQAAAHHQRAEGSTGGMGESLSRSEFVDRALRQAVTRESTKLQSGMTLLATVGATAPFVGLLGTVWGIYGALIKIGATGSASIDAVAGPVGEALIMTAIGLFVAIPAVFAFNFFSKVNSSVIAKFDTFAHDLHDFFATGSRVR
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APOC4_RABIT
Sequence: MLLPRRGLRTLPSLCLYILVLVWVVACEPEGTPTPLPAPEESRWSLVPSSVKELVGPLLTRTRERWQWFWGPGALQGFVQTYYDDHLRDLGPRAQAWLTSSRDRLLNTAQGLCPRLLCGDKDQD
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4, PARP.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y674_TREPA
Sequence: MRPLMAGKRRKDILPLEEALRAQSAFARTLRTWEGARRAAVRSATVRARRRGALPSSQAAAAPRVSLMEVALARYGLFDKDAAGACAEYARQRRTFSIHSRRGRRKLRTAVPEARLDLHGMTCSEARSALDSFFAQARERLLQKVEIVHGKGHHSKGGSVLAPSVKRYVQAHPHAGELFHPAERRGGKGTTWVLLKRSVPLH
What are the official names of this protein?
Uncharacterized protein TP_0674.
Protein: RUVA_LISMH
Sequence: MYDYIKGTVTTITPEYIVVEAGQIGYQIITGNPFSFQRLEGTEAQVFLYQHVREDNISLFGFQTTEERYLFKKLLSVSGIGPKSALAIIASGDVVPLISAIESEDDVYLTKFPSVGKKTARQIILDLKGKLADVVASEIVYVAPENDMVAGLSPQLEEAVLALEALGYSTRELKKVIPKLAKEEDLTSDAYIKLALQLMTK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: IF2_HYPNA
Sequence: MSDTNDQGNSGGRKPLTVVRKTSGTVKQSFSHGRSKQVVVETKKRRPVSSGGGQGGDSGPSTPSASDGMEAKLVALAAKLGITVAELKARQKVLEQRKAEEASRAKDTEAERAAQDRLRTEQERKQQEAREREEAELRRRAEEEAAKLADVASREAVERPSKAPRAAPAAQTPPAADGEADAGRSKRSSGGGASKPARDDRADRAREVATKPSRGDAERRRGKLTIASALGDDADRQRSLASVRRARERERERRVGGGDSNDKTSIEVTLPETITLQDLAQRMNERVADVVKFMFKQGEMLRGNDIVDADMAELIAGEFGHTVRRVSEADVEIGLEGTDDRDEDLQPRAPIVTIMGHVDHGKTSLLDALRKTDVAGGEAGGITQHIGAYQVQLKSGERITFLDTPGHAAFTAMRARGANATDIAILVVAADDSVKPQTIESISHAKAAGVPIVVAITKSDLHDANPEKVLTDLLQYDIQVEAMGGVTQAVKVSAKTGAGLDELTDAISIQAEILELKANPNRQADGVVIESKLDKGRGPVATVLVKRGTLKRGDIVVAGANWGKVRALVDERGQQLADAGPSLPVEVLGLDGAPDPGDAIVVVDSEARAREITEYRIRTKRQVAGNASVAARASLDQLMNRLKDGAIVTSELPIVLKGDVQGSVEAITMSLDKISTEEVRAKVIHGAVGGISESDVLLARSSNAPIFAFNVRANKQARDLAEREGVEIRYYSIIYDLLDDVKATLSGMLAPEKRETFLGYADILEVFNITKVGKVAGCRISEGKVMRGCGVRLLRDNVVIHEGKLKTLKRFKDEVSEVNAGMECGMAFERYDDIRVGDKIECFQVEEIARTLA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_FERNB
Sequence: MSSSFKRKIASVNVRVASPEVIRNWSNGEVKKAETINYRTFKPERDGLFCERIFGPVKDYECACGKYSGKKYEGTVCEKCGVKVESKDARRRRFGHIELAAPVTHVWYLKNSPSVIATLLDMTVKDIETIVYFGSRRVNERVVIVTDPKNTPFIKGSILNQTEYEIYAQKWDFEVSPAYIVKEPRSPLVSDIDGEVHIKHEKTHTDRELYWIVVKNISRTELKVYTGMVLNFKDNDQVNQGDEIVSEKRVEAIFAPFDGTVEVDEISETITINPLPTSKNNPITFSLPYGVRALVKNNEKVKKGQQLTTETILNSIVAPVSGTIRYSKQLNLRPLENGLYEVLTNGVIYIENVQNIKQYPVFEGAPIQVEDGQMVKAGDILADRFLFEEEKLTIEEYKLFSEYYPGMFVVEEQIENDKPIMVITDIDPSVSEETGIKKGQVITQQDYEAYSRIYPGKIEAETGAMAIKKLLEKIDLEVMKAEIEAELKKIPKSSVRAKKLLKKMKIVKDLIDSQTKPEWMVLEALPVVPPEIRPMIQIDGGRFATTDLNDLYRRVIMRNNRLKKLLEMNAPEVIVRNEKRMLQEAVDNLIFNGKIGKAYVDRNGRQLKSLTDLIRGKKGRFRRNLLGKRVDYSGRAVIVVGPHLKIHECGLPKKMALELFEPFVIAELSKEENTEAPQTKVKKYRKELQREDPKAWEKLEKVIQGRVVLLNRAPTLHRMSIQAFEPKLIEGNAIQLHPLVCPPFNADFDGDQMAVHLPLSPAAQAEARLLMLSRYNIISPAHGKPISMPGKDIVAGVYYLTMVDKNYDKIEPENIKWKFANPEEAELAYEFGFIKLHEPIIIKINDKAIKTTFGRVIFNSILPEELRDYNKTFGKNGIKDVVYKTFKTHGIDRTADLLDSIKDLGFHYATISGLTISLKDFMISPKKNEIITNAMKKIEYIEKLYDDGLLSDEEKYKETIKIWTETTNLVQEETYRYLGENPFNPVYIMVDSGARGNKDQLKQLSGMRGLMADPSGRTIEIPIISNFREGLSVLEFFISTHGARKGSADTALRTSSAGYLTRRLVDVVQSVVVTEPDCGTHEGVRATLLKSSDNFVVEKIEDFIFGRVLAKDIYEPGTGNILVNPNTNKSYTRDTVILDEDAKFLSNYKKRVNVVEESILDLSVGNIPEVYAELAEDIDTPSGLIPSETEIDWDVVRKLRDAGIKNVKIKLYPIVGSVISEEIVWDKDRKKQIAVEEEQVDVALAKLLEENNIDSVYVRPEIYVRSVLTCESEHGVCAKCYGLDLSNHKVVTVGESVGIIAAQSIGEPGTQLTMRTFHTGGIATTADITQGLPRVEELFEARKKTKDPEGIFSKVKGTVVDISNDEPKKIYIQDELGGIHEYEVPSRVRVNVTVGQKVLPGQSLTSGSLKVRKILEELGPEETATYLLKEIKRVYVQQGVDIHDKHFELIIRQMLNKAEVIDSGDTEFLPGDLVPISLLNKVNREIMEGNAKVEMNRKKIIGRELAKHIIVKNEDGEIVELAAEGEEVTEELLEKLIEYGIKEVVIMNHDKEKEVYQILPKETVKYRRRLLRITQASLEYEGWLSAASFQQTQQVLTDAAIKGAVDYLKGLKENVIVGQLIPAGTGFDIFSSVQYEETPRLAKEEKEKFA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.