PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_AGRRK
Sequence: MTARMDKRFAALKAEGRPALVTYFMGGDPDYDTSLGIMKALPEAGADVIELGMPFSDPMADGPAIQLAGQRALKAGQTLKKTLQLAADFRKTDGDTPIVLMGYYNPIYIYGVETFLDDAIAAGIDGLIVVDLPPEMDDELCIPAIRKGINFIRLATPTTDEKRLPAVLKNTSGFVYYVSMNGITGSALPDPSLVSGAVKRIKQHTDLPVCVGFGVKTAEHAKLIGASADGVVVGTAIVNQIATSLTKDGKAGADTIQAVATLVRGLSTGTRSARLVAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL311_ARATH
Sequence: MEKGKGRKEEVVTREYTINLHRRLHSCTFKKKAPNAIKEIRKFALKAMGTKDVRVDVKLNKQIWSKGIRGPPRRIRVRVARKRNDDEDAKEEFFSLVTVAEIPAEGLSGLGTKVIEEEE
What are the official names of this protein?
60S ribosomal protein L31-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: PTPA2_CANAL
Sequence: MSYITPTKRIFTPEDLSKWVGSPTYNTVLDFIVELQSSVTGKSNDSSYETSSIIDKLSKLLSKVDNLITLHPAHDSVSRFGKIEFRDFYSDLSSKAEEYISEITATAIQETSAYFIESWGNSTRIDYGSGHELNFICFLLCLKELGQITSADYEGLVLKVFTQYMSIMRKLQKEYWLEPAGSHGVWGLDDYHFLPFLFGAAQLSTHPHMKPKSIHNDELVEMYSTKYMYFECINFINKIKTIPNHQGKLSLRWHSPMLDDISAAKNWDKIREGMVKMYKVEVLGKLPIMQHFMFGSLLKCPEGIPEHTDENGHGENPEDHCGHAHVNTWGDCCGIKIPSGIAASESLKHERKGNIPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQE_METC4
Sequence: MNAPTPAPSPVDVIPAPVGLLAELTHRCPLRCPYCSNPLELDRRSAELDTQTWLRVLTEAAGLGVLHVHLSGGEPTARPDIVEITAKCAELGLYSNLITSGVGGALAKLDALYDVGLDHVQLSVQGVDAANAEKIGGLKNAQPQKMQFAARVTELGLPLTLNSVIHRGNIHEVPGFIDLAVKLGAKRLEVAHTQYYGWAYVNRAALMPDKSQVDESIRIVEAARERLKGQLVIDLVVPDYYAKYPKACAGGWGRKLMNVTPQGKVLPCHAAETIPGLEFWYVTDHSLGEIWTQSPAFAAYRGTSWMKEPCRSCDRREKDWGGCRCQALALTGDAANTDPACSLSPLHAKMRDLAKEEAAETPPDYIYRSIGTNVQNPLSEKAPL
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: VE2_HPV69
Sequence: MENLCQRLNACQEKILDYYELDSDKLSDQIDYWKLVRYECAIFYKAREGNMQCINHQVVPSTTVCKEKAWQAIELHIALQSLMNSEYGKEKWTMRDTCYELYVTEPKHCFKKEGTTVTVVFDCNKENTMDYIRWTSVYYKTDMGWCKTNGEVDYKGIYYMHGCCKQYYVDFKQEALKYGTGLQWDVHVCGQVICCPEFVSSTSGDQISTAQTAEPLSNNTTQTPETTCVPRCTEETPAPETAKRRRLSGPNTPVTTTSVTRPRSSLEHTDNVLHSNSGSNNPGRGTCSDQTVFIVHLKGDTNCLKCLRYRFKKHKGLYCKVSSTWHWTSNTNQGIVTITFDSETQRASFLTTVKIPQSITSTLGIMSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RS8_META3
Sequence: MSLMDPLANALNHLSNCERVGKDVAYVQPASKLIGRVFKVMQDKGYMGNFEYIEDGKAGIYKVELTGHINKCGAVRPRYAVKKTEFEKFEKRYLPAKGFGLLIVSTPKGLMTHDEAKSNGLGGRLISYIY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TRPF_BRADU
Sequence: MSLLVKICGLSTRETLETALDAGADMVGFVFFPPSPRHLSLELGRDLGRQVNRRALKVALTVDADDATLDNIMDALSPDIFQLHGKETVARLRDIKQRFGRPVMKAVPVATSADLAVLPGYAAVADRILFDARAPKDATRPGGLGAPFDWHLLENLDLNLPYMVSGGLHADNVAEALRITRAGGVDVSSGVESAPGVKDPEMIKAFIRAARATQDASQELSVR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RIMO_DESPS
Sequence: MKFHLISLGCAKNLVDSEVVLGCLRDAGWEMTDEQDADLLLVNTCGFIQPAVEEAVEEILALVDIKADFPEKKIVVLGCLVQRYKEQLLESLPEVDLFVGTEGVANIAEYVGKLIAGEEQDKVIMPTEFLMTAKVPRQQSTPFFRAWVKITEGCDNRCSYCMIPSIRGPLRSRSVADVLEEVQAMVASGVQEISLIAQDLTAYGDDLGDDVNLLVLLKELLAKTSVPWIRLLYLYPSELLDELLQLMAANPRIVKYLDIPIQHVNDRVLHLMNRPYGRADLEEFVDKARAHMPDIALRTTFLVGFPGETEEEYAEIGEFLRVRKLDHVGVFPYSNEEGAPSEHFPDQVDDEIKESRCARLLELQQELSTEIQKKYVGTVQKVLVEGVSEETDLLLEGRTQYQAADVDGRVYINEGQVVAGEIVDILITDSQQYDLVGGVVSVE
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLA_MICMP
Sequence: MNVFFMFSLVFLAAFGSCADDTRPLGECFREADYEEFLEIARNGLKKTSNPKHVVVVGAGMSGLSAAYVLAKAGHKVTLLEASEGVGGRVKTYRNKQEGWYINLGPMRLPERHRIVREYIRKFHLPLSEFVQENENTWYYIKNIRKRVSEVKKNPDLFEYPVNPSEKGKSASQLYQESLEKVIDELKRTNCNHILNKYDTYSTKEYLIKEGNLSPGAVDMIGDLLNEDSSFYLSFIESLKSDDIFSYEKRFDEIVGGFDQLPISMYQAIAEMVHLNAQVIKIQHNAKKVIVTYQTPAKTLPSVTADYVIVCSTSRAARHIRFQPPLPTNKARALRSIHYRSAIKIFLTCTKRFWEADGIHGGKSTTDLPSRFIYYFNQNFTNGIGVIMAYVLADDAKFFQPHDLKTNADIVINDLSLIHQLPKEEIQALCRPSWIQKWSLDKYAMGSITSFTPYQFLDYFEIAAAPVGRIHFAGEYTAKHHGWIDSTIKSGLRAARDVNRA
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:29900074, PubMed:31129208).  Shows activity on L-Leu, L-Trp, and L-Tyr (PubMed:29900074, PubMed:31129208).  Is not active on L-His, L-Ser, L-Arg, L-Ala, L-Glu, L-Cys,L-Lys, L-Val, L-Ile, and L-Thr (PubMed:29900074).  Induces apoptosis in Jurkat cells through a hydrogen peroxide-mediated signaling pathway dependent mostly on CASPASE-3 pathway (PubMed:31129208).  Remarkably, does no induce toxic effect on peripheral blood lymphocytes (PubMed:31129208).  Also exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, and antiparasitic activities, as well as regulation of platelet aggregation (By similarity).  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions (By similarity).  Shows antibacterial activity against S. aureus, but not against E. coli (PubMed:29900074).
What are the official names of this protein?
L-amino acid oxidase, LAO, MipLAAO1.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_ACIET
Sequence: MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVNFSTAEPAADGDNQ
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: Y417_STAA3
Sequence: MGYIKRMALYMSVFLLIIFIVGCRNMKDEQKKEEQTNKTDSKEEQIKKSFEKTLDMYPIKNLEELYDKEGYRDGEFKKGDKGMWTIYTDFAKSNKQGGLSNEGMVLYLDRNTRTAKGHYFVKTFYNKGKFPDRKNYKVEMKNNKIILLDKVEDTNLKKRIENFKFFGQYANLKELKNYNNGDVSINENVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPVLKMHIDGNLKGSSVGYKKLEIDFSKGGKSDLSVIDSLNFQPAKVDEDDE
What are the official names of this protein?
Uncharacterized lipoprotein SAUSA300_0417.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PFA5_CANGA
Sequence: MGFAEWRLRNKYWTIYIVPLVVLLLMIYGTWAYCHKLCYERVYRDFGHKATAIGLICTCCVLDALIIAIWVLIVSCGPGHQPGVAPHLLVDSADLENTTVAPNCYQSDPHGYPVWCSNCQSLKVGRTKHSSHQGHCVPRFDHYCVWLGAVIGFKNYRLFVQFVFYFAVLLMIVWITISVYIRDIRQYHARLNANLIVLLIISGIGWLMTSGLFVSYIYYMSQNLTSIEVIDLKKRKRTPELSMQRLYCYYNSDDHYRYVVKLDNDFKGSVYKKHWLKNIKEFMGSNPMLWFIPLPQYWHESPLANGERDVNTIVSPYQEEVGPHTIDYIKKRIESGEYIHKFKEPGREKTHL
What are the official names of this protein?
Palmitoyltransferase PFA5, Protein fatty acyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYY_METMJ
Sequence: MDPYELVTRNTVEVVTDEELRALIDRPVRRVYTGYEPSGEIHLGHMVTVNKLMDLQQAGFEVTVLIADLHAFLNRKGTMEEIRETAEYNRRCFEGLGLRGANYVLGSDVQLTPEYELAVLELSQAITLNRAKRSMDEVGRQMDNPTVSQMVYPIMQMVDIATLGVDAAVGGIDQRKIHMLAREHLPSIGYPAPVCIHTPIINGLDGKKMSSSAGNVISVADSEEDIKKKMKKAFCPPEVENNPVLEILRYHVFPRAGAVAIRRPEKFGGDREFAAYEDLERAYAAGEIHPLDLKNAAAAHLIDILAPVHDYVCSR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILL8_ORYSJ
Sequence: MAPPNASARLLLLVAAAAAVVLFAHLPTTTTAASPALKALGEDLLAAAGAAGFAGWLSGLRRRIHQRPELAFQEVRTSELVRAELDAIGVPYAWPVARTGVVATIDGGAGAGPVVALRADMDALPLQELVDWEFKSQEKGKMHACGHDAHVTMLLGAAKLLQSRKDELKGTIKLVFQPAEEGHAGAYHVLESGLLDDVSVIFGLHVIPNLPVGVVASRPGPFMSAAARFAATFTGKGGHAGVPHDAVDPVVAVSSAVLSLQQLVSRETDPLEAAVVSITILKGGDAYNVIPESASLGGTFRSMTDEGLAYLMKRIREIIEAQAGVNRCAAAVDFLEEELRPYPATVNDDGMYGHAKAVAEAMLGEANVRVAARSMGGEDFAFYARRSPGAFFFIGVGNETTMGPAAAVRPVHSPHFVLDERALPVGAALHAAVAIEYLNKHDCS
What is the function of this protein?
Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA).
What are the official names of this protein?
IAA-amino acid hydrolase ILR1-like 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: TAL_ACIC1
Sequence: MTDPLAELSAAGVSIWIDDISRDRLQTGNLAALIRDRHVVGVTTNPTIFGKAIEGSARYQDQLRDLAVRGVDVNEALRALTAYDVRWACDVTRPVFDATDGVDGRVSIEVDPRLAHDTEATIAEARALWWLVDRPNLFIKIPATVEGLPAIAQCLAEGISVNVTLIFSVKRYEQVIDAFFDGVERAIEAGHDLSRLASVASFFVSRVDTEVDKRLEKIGGEALQWKAKAAVANARLAYRTYEEKFATPRWQALAAKGARPQRPLWASTSTKDPSLPDTLYVTELVAPGTVNTMPESTLQAVYDHGVIRGDTIRGYYADAQATLDALATLGIDYDDVTDTLEREGVEKFEASWTELAAAVTRSLERARRERGR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_FRATN
Sequence: MSKDFILAVDQGTTSSRAIIFDKKGNIRKIAQKEFTQIYPKSGWVEHDAMEIWGTQSGVMREALEFGRVKPDQIAAIGITNQRETVVVWDKETGDPVYNAIVWQCRRTSSICDEIKRDPQFVKYIKENTGLVVDAYFSGTKVKWILDNVEGAREKANAGKLLMGTIDTWLIWNLTRGKVHATDYSNASRTMLFNINSLEWDKKILDYLNIPESMLPEVKNSSEVFGVTDSHTLGGAEIPIAGVAGDQHAALFGHCCFEKGMAKNTYGTGCFALMNVGDKPVYSDEGLLTTIAWAENGKPTYALEGSVFIAGAVIQWIRDGLGLVRSAEDSEYYATKIDSTNGVYLVPAFVGLGTPYWDMYARGTIVGITRDTKREHIIRAALEAIAYQAKDVLECMKEDTGLDLAGLRVDGGAVQNNFLMQFQSDILQSEISKPKINEITGLGAVFLAGLAVGFWKDKQELKSILTTEKVFEPQKDSQAVAHDYRGWKKAVERSKAWAEC
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: YQGF_KORVE
Sequence: MKEPSAVHGRILALDFGTRRIGLAVSDPLGITAQGLQTLLRKNKRTDLAALRSVIEQNEIREIVVGLPLRLSGADSSSTEKAREFAAWLEKEFALPVHMWDERFTSVEANRVLRESEMSIKKRGEAVDRLSAVLILQAFLERRGIDREEPLSS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_RHOPT
Sequence: MAQHDPIGLIAPNAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLISVPLSPASVRNVMADLEQLGLIYAPHTSAGRLPTELGLRFFVDALMQIGDLTEPERQSIQAQLSSVGRAHTVEAALGEALTRLSGLTRAAAVVLTAKANVRLKHIEFVRLEPERALVILVAEDGQVENRVLTLPPGVPSSALIEAANYLNARIRGRTLAEARLELESLMVQNKAELDQLTQKVIAAGIASWSGGDGEDRQLIVRGHANLLEDLHALDDLERVRLLFDDLETKRGVIDLLGRAESADGVRIFIGSENKLFSLSGSSTIIAPYSDGAGHIVGVLGVIGPTRLNYARVIPMVDYTARIVSRMLGG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: Y020_BACCZ
Sequence: MMRGGMGNMNNMMKQMQKMQKEMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKVKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCE33L0020.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ACKA_STAAT
Sequence: MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPMC_ECOLX
Sequence: MEASITVSHSFQCHPRDALRALCAALLTSAATSRNSLASSTHAAPVWRWAFSHSAACASLACWVWLMTCRASSASVAMLWASGSICSANSLMPLDFFTLSIAFMVYCLPVFL
What are the official names of this protein?
Uncharacterized mobilization operon protein C.
Protein: PYRI_YERPS
Sequence: MMTQDYKLQVEAIKCGTVIDHIPAQIGFKLLSLFKLTATDQRITIGLNLPSKRSGRKDLIKIENTFLTEQQANQLAMYAPDATVNRIDNYEVVKKLTLSLPERIDAVLTCPNSNCISHNEPVDSSFTVKAQRGEISLKCKYCEKEFDHLAVLHAD
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: ARGB_POLAQ
Sequence: MTKHLPTISDISPLLKAEILAEALPYIRAYHGKTIVIKYGGNAMVEERLKESFARDVILLKLVGMNPVVVHGGGPQIDEALKKIGKTGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGQAVGLTGKDGGLIHAKKMMIPSDAEPGKKIDIGFVGEIEAINPAVVKALQDDAFIPVISPIGFSAEGQAYNINADLVAGKMAEILHAEKLVMMTNIPGVMDKDGKLLTDLTAREIDALFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTEQAFGTMIRSR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP3_CANAL
Sequence: MSNLTPIATYNLALQPFQPVPAIEDDFPISIRITLASLDPEAADDKAEPSSLRILKKSNSLLSDDYFEDDDDDEEEDDEEDELDDEEEEEEAEEEKSSKKSNGKKSSKKDEDEEEDDEEEDDEDNDEDDVSEYIVCTLSPKHQYQQTLDLTITPDEEVYFVVTGSYPIHLTGNYIEHPADQDEEDYDNEDEDYDDEYDLSPDEDEIIYGAPLDDEYDDEEESEEEGTPKIEEIVEEKEKVKESPKESKKRVAEESTSKKSKKAKKDEKKSVQFSKELEQGPTGSTLVEKDNKKATPTKDKKETPVKDDGDKKKKFPTKTLLGGVITEDRKIGSGATAKSGAKVGIRYIGKLKNGKVFDKNTSGKPFSFKLGKGECIKGFDLGVTGMAVGGERRVIIPPKMGYGSQALPGIPANSELTFDIKLVSLK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 3, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACEA1_MYCBO
Sequence: MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH
What is the function of this protein?
Involved in the persistence and virulence of Mycobacterium.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase 1, ICL1, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: CYRPA_PLAF7
Sequence: MIIPFHKKFISFFQIVLVVLLLCRSINCDSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNSEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTTAGCYGGTFVKIDENRTLFIYSSSQGIYNIHTIYYANYE
What is the function of this protein?
Essential for the invasion of host erythrocytes by blood stage merozoites (PubMed:22593616, PubMed:25583518, PubMed:27374406, PubMed:28195530, PubMed:28195038).  Required for the assembly of the PfRH5 adhesion complex (or invasion complex) composed of CyRPA, RH5 and RIPR at the interface between the merozoite and the host erythrocyte membranes (PubMed:25583518, PubMed:28186186, PubMed:28195530, PubMed:28195038, PubMed:30542156).  This facilitates the binding of RH5 to host receptor BSG/basigin, which leads to the establishment of a tight junction between the merozoite and host erythrocyte membranes and allows Ca(2+) release into the erythrocyte (PubMed:27374406, PubMed:28186186, PubMed:30542156).
What are the official names of this protein?
Cysteine-rich protective antigen, Inactive sialidase CyRPA.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, microneme lumen. Cell membrane; Peripheral membrane protein; Extracellular side. Host cell membrane. Note=In late schizonts, colocalizes with RIPR in the microneme lumen (PubMed:22593616, PubMed:25583518, PubMed:27374406). During merozoite invasion of host erythrocytes, secreted at the merozoite apical surface where it colocalizes with RIPR and RH5 at the interface between the merozoite and the erythrocyte (PubMed:25583518, PubMed:27374406).