PharMolix/UniProtQA huggingface dataset:
Protein: SCA2_RICFE
Sequence: MSLQNSHSKKYVLTFFMSTCLLTSSFLSTSARAASFTQLANQIPTLSGLSEVQRKQKWNSYTLQEKQEAWRRAKLTPDFVQAMIDMQTGFTESDLSSRNNKTRHKAREKKSELDLYIAGTKQGFKEKVDGYISQGKIPTPEEAAQNLEIDYDAKKTDNKLEKNQNVRRVEKDKKALLDLYIHSITTSVKEKEYITTGQVPELGELEKALNISKEEAKHRRTIIRDQVMANERPKLVRSGTVLTKKELHKRFGKDTTTDDTKYIDDITTEVMYTKKQGYVNTDFLPKISEIMNEFKVDKGRANLYLNQIKAGIEAKLLADNNQTTTKPFTKHSRTTTNTAGISSGVPFDTGRTKPETKSFDFKRSMYSLLNRKQEDQLSKTEQHLKQQIKLEENKEEFKEILTKNPIDALLFAEQSNLGNSFKQEAISNIDLSKDISRILFTVDDKGNRTILNTILTTTPEHKDELIKQAQHHAIQTLPTSISDKDVSDKKKLTLATLAATEDKKVLEEALDNWLSTNGYKRKPEVESLISILLSDETTLKAGIDKIFELPVENNVNNNSNKGQNGTPILPPTPPLNGSMPPSPPPPLLNGTPTSTAFNNSNPNHKFDLKNFEATYPRLYKSYNEFIQNTTSASQSQATTTSNNIPDTKAKMGESLELLKQKVAKQNEVIGLIHNEVTKLYNFSPKTFVNLFNTENEEIIKKIEQIAKREDIQKILQDNDIKITSTFVSKIFNESLEQTKQRLRSSNIINAKQYKRIEQYANKQECVTEFLRITNPLEQLKFANKYINILGQSTFNGKLNELIENPNKLTFSQKINFVLQGYQELTREIPTAKANLNKLKQNILEKIEIQQLIANKDISRKDLLDILNNKNPELLKSLLEAKVILEENKLNNSANEVDLKEIIPSLNYLTSEQLTSLINRITIEGVKTALKAKWQQENKTVSNNTEKPLIYNNGTPMPPPIPNGNSNFGTNDYLISMGYTQEFIDRMDKVKPNNNFGKNHNYTATDFKSNVGKNYYESTSKLGGTDILLTDSQKLENAIKKEVLAKYIEEPNRDMQDDSLLKQAFEEKFYYAEDKNTKVIPKPSEVNFDPNFIGPRTEVGQEIYELYEQELLKLARDPVFIEYVKNNNNTQKDERELLISFIEQIESKRPELEQKYGSDVQSEDNNQEKKVGHLNMKQFQSLFQQENESANDESSTKDDPQPEDSNKKSEKSDSETALSPRLLSSNDSKNDKSSDDKKSLLVLRSSEEESKKDIALESEDEAIDMSFKTEAIAEQDEATQRQQVSDDTNRKVAILVKATSTLHKPVHYNILSDRLKVAAIGAGDEEASINRGVWISGLYGINKQGTWKNIPKYQGRTTGVTIGADAEFINSHDVIGIAYSRLEFQIKYNKKLEKTAVNGHLLSIYGLKELIKGFSLQAITSYGHNYIKNKSKSINNIIGKYQNNNLSFQTLLNYKYRTKYDLHFIPNIGFKYDYSRASNYKEYNVDIENLMNQKKSNQSFESSIGGKIVFKPIATVNNIILTPSLYGNIERHFNNKNTKVNAKATFKGQTLQETIIIPKQPKLGYNIGSNILMSKKNINVLLEYNYYTHRKYQSHQGLIKLKVNL
What are the official names of this protein?
Putative surface cell antigen sca2.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS19_NATPD
Sequence: MSSEYQIGHEGEFTYRGHTLDELQEMELDEVAELLPARQRRTIKRGLSVEQEKLLDEAREAGEEETANNPIRTHLRDMPILPRFVGLTFAVYNGQSFERVEVEPEMIGHYLGEFQLTRTSVEHGQAGIGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: AROB_CERS1
Sequence: MTVDAVRVELGARAYEVRIGPGLIARAGAEIAPLLRRPKVAILTDETVAGLHLDPFRQALAEAGIASSALALPAGEATKGWPQFARAVEWLLEEKVERRDVVVALGGGVIGDLAGFAAAVLRRGVRFVQVPTTLLAQVDSSVGGKTGINTAQGKNLVGAFHQPSLVLADIGVLETLPPRDFRAGYGEVVKYGLLGDADFYEWLEEAGPRLAADTEARQRAVRRSVEMKAEIVARDETEEGDRALLNLGHTFCHALEKATGYSDRLLHGEGVAIGCALAFELSQRLGLCAQEAPSRLRAHLRAMGMKVDLRDIPGDLPSAEALLALMAQDKKVVDGKLRFILARGIGQAFVADDVPGDVVRTLLEDALAQR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_OLEA2
Sequence: MDIQETINQMGKKAAAAARAMRAASPSAKTSALLSLAQLIRQENKAITEANARDLAAAADRGLDAPRMDRLRLTDAVIEEMARACEFVAGLPDPIGATEKQWQRPNGLLVGKMRIPLGVISMIYESRPNVTVDSGILCLKAGNAVILRGGSEAFHSNMMLASLIHRALILAGLPQDAVQVVPSTDRGAIKALCELEEYIDVIIPRGGETLIRTVVADARMPVLKHYKGVCHAYVDEGADLEQACEIIFNAKVQRPGVCNALEGLLVHRSEAHTLLPAVAQKLGDAGVSFRACPRALPLLAPHGVPMAETDPGTEFHDLVMVVKVVDSQDEAQDYIAQHGSNHTEIICTRNHQNAMRFVREVDASMVAVNASSRFNDGGQLGLGAEIGISTSKLHSYGPMGVEELTTTKFVVLGNGQIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TACHC_TACTR
Sequence: DYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR
What is the function of this protein?
Binds to chitin.  Shows strong activity against E. coli (IC(50) is 1. 2 ug/ml).  Is also very active against S. aureus (IC(50) is 0. 8 ug/ml), C. albicans (IC(50) is 0. 9 ug/ml) and P. pastoris (IC(50) is 0. 3 ug/ml).  Binds to chitin (5. 2 uM are required to obtain 50% of binding).  Causes hemolysis on sheep erythrocytes, probably by forming ion-permeable pores.
What are the official names of this protein?
Tachystatin-C.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_OENOB
Sequence: MLNIRILVVGKIKEKYFRNALDQYLKRLSRFTKIEIIEVKDEATPEKASKSENLEILQTEGGRLLDKINNRDFVIALAIEGKLITSPDLADMIREIPLDGYSTIDFVIGGSLGLSNEIKNRANAKISFGRITLPHQLARVLLTEQIYRSFMINEGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_SYNC1
Sequence: MSEIVDIYAREILDSRGNPTVEVEVFLESGAMGRAAVPSGASTGEREALEMRDGDAARYLGKGVLKAVDNVNNVIAAELLGWESTEQTALDQKLIELDGTEFKSTLGANAMLGVSLACAKASAEELGLSLYQYLGGPNGRELPLPMLNILNGGAHADNNVDIQEFMVMPAGADSFKEALRMGAEIFHALKSVLKKRGYNTAVGDEGGFAPDLKSNEEALEVIMEAIKAAGYKPGEDVLLALDVAASELYADGKYNLANEAQPLKTAAELTDFYADLVDRYPIISIEDGMAENDWDGWKILTDKLGKRIQIVGDDLFVTNTKIFKEGIDKGIANSILIKLNQIGTLTETLEAIEMAKRAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSACRTDRVCKYNQLLRIEDQLGEAACFNGKDVFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MTMV_KOCVA
Sequence: MEYLNDKDQHLIDKLSKKINDNNQYLGFLNTNTKELTHRYHIYPAMMIPQLAKEFIELTQQVKPEIKKLYDPFMGSGTSLVEGLAHGLEVYGTDINPLSQMMSKAKTTPIEPSKLSRAISDLEYSIREMTILYHEGNYKISNLPDFDRIDFWFKEEVIISLQLIKNCINEFIEDDLKTFFMAAFSETVRHVSNTRNNEFKLYRMAPEKLEIWNPNVTEEFLKRVYRNELGNMDFYRQLENVGNYSPKTIINKQSNIKLPEEFKDEMFDIVVTSPPYGDSKTTVAYGQFSRLSAQWLDLKIDDETKINQLDNVMLGGKTDKNIIVNDVLEYLNSPTSKSVFNLISHKDEKRALEVLQFYVDLDKSIKETTRVMKPESYQFWVVANRTVKMISIPTDIIISELFKKYNVHHLYSFYRKIPNKRMPSKNSPTNKIGNHSVTMTSEIILMLKNYINKS
What is the function of this protein?
An alpha subtype methylase, recognizes the double-stranded sequence 5'-CCWGG-3', methylatES C-2 on both strands, and protects the DNA from cleavage by the MvaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.MvaI, M.MvaI, Modification methylase MvaI, N-4 cytosine-specific methyltransferase MvaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: MSX2_HUMAN
Sequence: MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
What is the function of this protein?
Acts as a transcriptional regulator in bone development.  Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation.  Probable morphogenetic role.  May play a role in limb-pattern formation.  In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE).  Binds to the homeodomain-response element of the ALPL promoter.
What are the official names of this protein?
Homeobox protein MSX-2, Homeobox protein Hox-8.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGALE_ASPFU
Sequence: MKSLLKRLIALAAAYSVAAAPSFSHHSSQDAANKRELLQDLVTWDQHSLFVRGERLMIFSGEFHPFRLPVPGLWFDVFQKIKSLGFNAVSFYTDWGLMEGNPGHVVTDGIWSLDEFFTAAREAGLYLIARPGPYINAETSAGGIPGWVLRRKGIIRSNSEDYLRATDTYMATLGKIIAKAQITNGGPVILVQPENEYTTWPNVSESEFPTTMNQEVMAYAEKQLRDAGVVVPTVVNDNKNLGYFAPGTGLGETDLYGIDAYPMRYDCGNPYVWPTYRFPRDWQHEHRNHSPTTPFAIMEFQGGSGDGWGGVTEDGCAILVNNEAVRVVYKNNYGFGVRVFNIYMTYGGTNWGNLGYYGGYTSYDYGAAITEDRQIWREKYSEEKLQANFLKVSPAYLTSTPGNGVNGSYTGNKDITVTPLFGNGTTTNLYLVRHADFTSTGSAQYNLSISTSVGNVTIPQLGGSLSLNGRDSKFHITDYDVGGFNLIYSSAEVFTWAKGDNKKRVLVLYGGAGELHEFALPKHLPRPTVVEGSYVKIAKQGSAWVVQWEVAAQRRVLRAGKLEIHLLWRNDAYQHWVLELPAKQPIANYSSPSKETVIVKGGYLLRSAWITDNDLHLTGDVNVTTPLEVISAPKRFDGIVFNGQSLKSTRSKIGNLAATVHYQPPAISLPDLKRLDWKYIDSLPEISTEYNDEGWTPLTNTYTNNTREFTGPTCLYADDYGYHGGSLIYRGHFTANGDESWVFLNTSGGVGFANSVWLNQTFLGSWTGSGRNMTYPRNISLPHELSPGEPYVFTVVIDHMGQDEEAPGTDAIKFPRGILDYALSGHELSDLRWKMTGNLGGEQYQDLTRGPLNEGAMYAERQGYHLPSPPTSSWKSSNPIKEGLTGAGIGFYATSFSLDLPEGYDIPLSFRFNNSASAARSGTSYRCQLFVNGYQFGKYVNDLGPQTKFPVPEGILNYNGVNYVAVSLWALESQGALIGGLDLVASTPILSGYRKPAPAPQPGWKPRRGAY
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Probable beta-galactosidase E, Lactase E.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2234_SHELP
Sequence: MFGKGGMGNLMKQAQMMQDKMAKVQEEIARMEVTGEAGAGLVKVTMTGSHSVRKVEIDPSLLEDDKEMLEDLIAAACNDAARRVEESQKEKMAEVTGGMQLPPGMKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Shew_2234.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: IF1_ALKOO
Sequence: MSKQDVIELEGVVKEALPNAMFIVTLENGHEVLGHISGKLRMNFIRILPGDKVTVELSPYDLSRGRITWRKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_RHOPT
Sequence: MLIDIIRAVILGIVEGVTEFLPVSSTGHLLLAERFFNLGEGNFWKSFAVLIQLGAILAILALYFVKLWRIALGMFTDANARRFVIGVLVAFLPAAVIGAAFGGYIKHYLFNPWVVCFSLIVGGAILLWVDQLDLKPRYHDATAFPLLTYFYIGCAQCTAMIPGVSRSGASIVAAMLLGTDKRSAAEFSFFLAIPTMLGAFVYDLYKNHADMTADNLIIVAIGFVVSFITAIIVVKTFLTYVTRHGFELFAWWRVIVGTLGLIALALGL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IOLC_BACVZ
Sequence: MKYTFNEEKEFDIVAIGRACIDLNAAEYNRPMEETMTFSKYVGGSPANIAIGSAKLGLKAGFIGKIPDDQHGRFIVSYMQGKGVDTSQMTVDREGRKAGLAFTEILSPEECSILMYRDDVADLYLEPSEVNEGYIANAKMLLVSGTALAKSPSREAVLKAVHIAKKHDVKVVFELDYRPYTWQSAEETAVYYTLVAEQSDIVIGTRDEFDVMENRSGGGNDETVRHLFAHSADLVVIKHGVDGSYAYSRSGEVFRAHAYKTKVLKTFGAGDSYASAFIYGLVSGRDIETALKYGSASASIVVSKHSSSEAMPAAGEIIELIEAQHSLNGK
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RIMP_CORDI
Sequence: MAFPTVEVLTELVTPVVAQHNMDLEGIRINKAGKKSLVAVSVDSDFRPDLDQLELVSNQISEVFDAGEAAGELSFGAGYTLEVGTPGLDQPLASARRWRRNRHRLVALEVEGKKSVERIGALNDDETAVIVVKRRGKKLVVRSVQLAENTQAVVEIEFAKPAEDELALTALEFDQALDRGEENK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELYA_ALKCL
Sequence: MKKPLGKIVASTALLISVAFSSSIASAAEEAKEKYLIGFNEQEAVSEFVEQVEANDEVAILSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPAISYIEEDAEVTTMAQSVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSISYPARYANAMAVGATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSLGSTNLYGSGLVNAEAATR
What are the official names of this protein?
Alkaline protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CATA2_WHEAT
Sequence: MDPYKHRPTSGANSAYWTTNSGAPVWNNNNALTVGHRGPILLEDYHLIEKLAQFDRERIPERVVHARGASAKGFFEVTHDVSQLTCADFLRAPGVQTPVIVRFSTVVHERGSPETLRDPRGFAVKFYTREGNFDLVGNNMPVFFIRDGMKFPDMVHAFKPSSKTNMQENWRVVDFFSHHPESLHMFTFLFDDVGIPLNYRHMDGFGVNTYTLISRDGKAHLVKFHWKPTCGVKCLLDDEAVTVGGTCHTHATKDLTDSIAAGNYPEWKLFIQTIDADHEDRFDFDPLDVTKTWPEDIIPLQPVGRMVLNKNIDNFFAENEQLAFCPAVTVPGIHYSDDKLLQTRIFSYADTQRHRLGPNYLMLPVNAPKCAHHNNHHDGLMNFIHRDEEVNYFPSRVDPTRHAEKDPMPPRVLSGCREKCIIDKENNFKQAGERYRSFDPARQDRFLQRWVDALTDARVTHEIQSIWVSYWSQCDASLGQKLASRLKIKPNM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: UBIE_YERP3
Sequence: MVDQEKETTHFGFRTVAKEQKEGMVAEVFHSVAAKYDLMNDLMSFGVHRIWKRFTVDCSGVRRGQRVLDLAGGTGDLTAKFSRLVGEQGEVILADINESMLRMGREKLRDKGIVGNVSYVQANAEALPFPDNYFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPLLEPLSKAYDAYSFHILPKIGELVAQDAESYRYLAESIRMHPDQETLKGMMADAGFENVTYSNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CDD_ECO5E
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLADAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHNIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: SYS_THEKO
Sequence: MLDIKLIRENPEIVKRDLIKRGETEKLKWIDEILELDKKWRENLKKINQLRKERNQLAVQIGKRKKAGEPIDDLLKRSNEIVKQIEELEKENEELKKKIDYYLWRLPNITHESVPVGESDEDNVPIRFWGKAKVWEGFLETFKEQSLGKMEYEVLSWRPRLHVDMLELLRGADLERAAKVSGARFYYLLNELVILDLALIRFALDKLIEKGFTPVIPPYMVRRFVEEGATTFDDFEDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIANAEEIFQALEIPYRVVNICTGDLGYVAAKKYDIEAWMAGQGKFREVVSASNCTDWQARRLNIRFRDKTHEKPRFVHTLNSTAIATSRAIVAILENHQTEEGVVKLPKALWKYTGFKEILPAHMKEKCCQD
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_BACLD
Sequence: MPINIPINLPAKQILESENIFVMDEKRAFHQDIRPLNIVILNLMPQKIKTETQLLRMLGNSPLQVYFTFLIPSTHTPKHTPRQHLEQFYTTFSSIRDRKFDGMIITGAPIEHLEYEEVSYWEELREILDWSKTHVTSTLHICWGAQAGLYHHYGIRKVKLPKKTFGVFEHRIMEKNERLVRGFEEFYYVPHSRHTDINMDDLKAVSHLKVLSISDEAGVCLIASKDEKQVFLTGHPEYDTDTLKEEYERDLARNMEIDPPVNYFKEGPDGAVPVNRWKAHATLLFMNWLNYYVYQETPYEWK
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_YERPS
Sequence: MTYHLDVVSAEKKMFSGVVQKIQVTGSEGELGIFPGHAPLLTAIKPGMIRIVKQFGEEEFIYLSGGILEVQPSVVIVLADTAIRGLDLDEARALESKRKAEAHINNSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVC_ALIF1
Sequence: MSNYFNTLNLREQLDQLGRCRFMDREEFATEADYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRQAAIDEQRQSYKNAKENGFEVASYETLIPQADLVINLTPDKQHTNVVETVMPLMKEGAALGYSHGFNVVEEGMQIRKDLTVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGWDIAKAWAAGTGGHRAGCLESSFVAEVKSDLMGEQTILCGMLQAGSIVSYEKMIADGIEPGYAGKLLQYGWETITEALKFGGVTHMMDRLSNPAKVKAFELSEELKELMRPLYNKHMDDIISGEFSRTMMADWANDDVNLFGWREETGQTAFENYPESDVEISEQEYFDNGILLVAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANTVARKRLYEMNVVISDTAEYGNYLFANVATPLLREKFMPSVETDVIGRGLGEASNQVDNATLIAVNDAIRNHPVEYIGEELRSYMSDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LSRF_ECO57
Sequence: MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVDAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE7A_HUMAN
Sequence: MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTALYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHSQSEIEVSVSARNIRRLLSFQRYLRSSRFFRGTAVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFELNSQLLPQENRLS
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:8389765, PubMed:9195912, PubMed:19350606).  May have a role in muscle signal transduction (PubMed:9195912).
What are the official names of this protein?
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.
What are the subcellular locations of this protein?
[Isoform PDE7A1]: Cytoplasm, cytosol. Note=PDE7A1 (57 kDa) is located mostly to soluble cellular fractions. SUBCELLULAR LOCATION: [Isoform PDE7A2]: Cytoplasm. Note=PDE7A2 (50 kDa) is located to particulate cellular fractions.
Protein: SYT_ECO7I
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFA_BPAPS
Sequence: MDCNRMVIMNSVNEETYYFGQRKLAWFAGSMKKDYIEAGSWDDKAKAVPYSVYREFALNPAPIGKTLGISEKGDPIWVDIPPKTKHQLITEAEDKKSGLMQGAREVISPLQDAIDLEMATQEETQKLTAWKRYRVLLNRLDTSNAPDIDWPKKPE
What is the function of this protein?
Chaperone involved in tail fiber assembly.
What are the official names of this protein?
Probable tail fiber assembly protein, P37.
What is the protein family that this protein belongs to?
Belongs to the tfa family.