PharMolix/UniProtQA huggingface dataset:
Protein: TIG_BURPS
Sequence: MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISRAENLRVAGQPSFAPKEDTQQESTYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAGKTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RLMN_RHIE6
Sequence: MSVMDAIDVTKPQAPKTSSGAEKPSLIGLSRQEMAAALREKGVAEKQIKMRVAQLWNWIYVRGVSDFDHMTNVAKDMREMLKQHFTIARPEIVEEQVSNDGTRKWLLRFPARGAGRPVEIEAVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQRLVRNLTAEEILSQLLLARDRLGDFPDREAPQGTIMPAEGRKVSNIVMMGMGEPLYNFDAVKQALLIATDGDGLSLSKRRVTLSTSGVVPEIFRTGEEIGVMLAISLHAVRDDLRDILVPINKKYPLKELIDACKAYPGLSNARRITFEYVMLKDVNDSLEDAKGLIKLLKGVPAKINLIPFNPWPGTNYQCSDWEQIEKFADFINSAGYASPIRTPRGRDILAACGQLKSESERMRKTERLAFEAMMIANHGADD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_HAES1
Sequence: MIEVDRIVSANAKVDDEYIDRAIRPKLLSDYIGQPQVREQMEIFIQAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYSVEDLASIVTRSAVCLQLEIDVEAGQEIACRSRGTPRIANRLLRRVRDYADVKNGGKITALIAQEALKMLDVDLAGFDFMDRKLLQAIIERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIATSRTYRHFGLEQIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GT253_RAT
Sequence: MLFIIRARACGGDARSWKQPDQLHPILFTNLRLPLQLIASSAGGATDHNVDNTTGMLQEWLAAVGRDYATVVWKSEDEARSYPDEQGPKHWTRERHQFLMELKQEALAFARDWGADYILFADTDNILTNNQTLRLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLVSLQTEETARLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNDHRYGYMNVGVKPHQGLEEEKTNFIHLILEALVDGPPMMASAHVSRPPKKPSKMGFDEVFVISLARRPQRRARMLSSLWEMEISARVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVAKGLARVVVFEDDVRFEDNFRKRLERLMEDVLTQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAHFWPRDLQAFSARPLLASPTHYAGDTEWLSDTETSSPWDDDSGRLISWTGSQKTLRGPYLHLAGSSGHSLHPHPRDEL
What is the function of this protein?
Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier.  Does not express any beta-galactosyltransferase activity in vitro.
What are the official names of this protein?
Probable inactive glycosyltransferase 25 family member 3, Cerebral endothelial cell adhesion molecule.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TRPC_PROM1
Sequence: MEIRRRPPNPSIKVANLEYAIPHPDSKPKNILEEIVWEKHLEVEIARKKVSLEDLKKKIKDLPKTKNFIDALRNSNSKPALISEIKKASPSRGIIREDFDAKMIGKMYQEGGANCISVLTDKKFFQGGFDVLVEVRKEIIIPILCKDFILYPYQLYQARAAGADAALLIAAILTDSDLKYLSKVAEHLGLTILVEVHDSEELERVLNINVFNLIGINNRNLKSFKTDLEVTKKLAKNYANQIKENSITLVSESGLFNREDLDLVKSYGADAVLVGESLMSQEDILGGVKKLVGNL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RL18_LEPIN
Sequence: MIDRLKKSISKTKRAERSRFKLKKLGSRPRLVFIKSNQYLSCQIIDDIQGVTLAYATTSEKTFTGEGKSKKDKGAAKVLGKLIAERGSQKGVKQVMLDRSGMIFHGRIAAFAEGAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TF2B_PYRAE
Sequence: MSVSNPPSSGKPLKLRVNKDSEGYLSLVTESGEVYKCPICGNDKFVYNYERGEAVCIVCGAVVQEQLLDLGPEWRAFTSEEKGQRARTGAPLTRLISEALTTVIDWRDKDVSGKELDIKRKLEVIRLRKWQTRARVQTSYERNFIQAAQELERLRSAMGIPRPCIEQALEIYRQALEKELVRGRSVEAMAAAALYMACRMMKMPRPLDELVRYTKASRREVARCYRLLLRELNVKVPISDPILYISRIAEQLKLSGEVVKTAIDILQKAKKAGITAGKDPAGLAAAAVYIASLMHGDNRTQKDFAVAAGVTEVTVRNRYKELAKALNIKVPVK
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: MSX1_LEPED
Sequence: MTSLPLGVKVEDSAFGKPAGGGASQAPSAAAATAATMGADEEGAKPKVPPSLLPFSVEALMADHRKPGAKESALAASEGAQAAGGSAQSLGVRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALIKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP6_PSEAE
Sequence: MAAETASGYIQHHLQNLTFGRLPNGDWGFAHTAEQAKEMGFWAFHVDTLGWSVLLGVVFLFIFRLAAKKATSGQPGGLQNFVEVMVEFVDTSVKDTFHGRNPLIAPLALTVFVWIFLLNLIDLVPVDYLPMLAAKITGDEHLFFRAVATTDPNATLGLSISVFALIVFYSIKVKGIGGFLGELTLHPFSSKNIVVQILLIPVNFLLEFVTLIAKPVSLALRLFGNMYAGELIFILIAVMFGSGMFLLSALGVALNWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_TROW8
Sequence: MAKRVLLASPRGYCAGVDRAVIAVEKALERHGPPVYVRKQIVHNVHVVGSLEKKGAIFVDQVDQIPPGAVTIFSAHGVSPAVVHSANERGLQVIDATCPLVTKVHREVIRFSKAGYFILLIGHSGHEEVEGTSGHAPDRVLVVNSPDEADTIDVPHTDKLVWLSQTTLSVDETLETVKRLRLRFPHIQDPPSDDICYATQNRQAAVKKIAPLSDLVIVVGSANSSNSVRLVEVALENGAKAAVRLDYADELDPALLDKVDVVGVTSGASVPEILVRDLLEVLARAGYTKVESVQTAVEDLVFSLPKGLRESRK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PPA5_RABIT
Sequence: MDTWTLLLVLHTSLLLPWAEGATPTLRFVAVGDWGGVPNAPFHTAREMANAKQIGKVVQMLGAHFILSLGDNFYFSGVQSVSDKRFQETFEDVFSDRSLQNVPWYVLAGNHDHIGNVSAQIAYSKVSKRWNFPSPFYRLRFRIPRTNVSVAIYMLDTVTLCGNSNDFLSQQPERPRNLELARTQLAWLKRHLADAKEDYVLVAGHYPVWSIAEHGPTHCLVKKLQPLLVKYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSTQHQRSVPNGYLRFHYGAENSLGGFAYLEITPKEMTVTYMEASGKSLFKTRLPKRAKA
What are the official names of this protein?
Tartrate-resistant acid phosphatase type 5, TR-AP, Tartrate-resistant acid ATPase, TrATPase, Type 5 acid phosphatase.
What are the subcellular locations of this protein?
Lysosome.
Protein: MCPT4_MOUSE
Sequence: MQALLFLMALLLPSGAGAEEIIGGVESRPHSRPYMAHLEITTERGFTATCGGFLITRQFVMTAAHCSGREITVTLGAHDVSKTESTQQKIKVEKQIVHPKYNFYSNLHDIMLLKLQKKAKETPSVNVIPLPRPSDFIKPGKMCRAAGWGRTGVTEPTSDTLREVKLRIMDKEACKNYWHYDYNLQVCVGSPRKKRSAYKGDSGGPLLCAGVAHGIVSYGRGDAKPPAVFTRISSYVPWINRVIKGE
What is the function of this protein?
Has chymotrypsin-like activity.  Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position.  Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein.  Involved in thrombin regulation and fibronectin processing.
What are the official names of this protein?
Mast cell protease 4, mMCP-4, MSMCP, Myonase, Serosal mast cell protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
Protein: HIS5_OCEIH
Sequence: MIAIIDYGAGNIKSLQFALDKLNKHSIVTTEAAEIKQADSIILPGVGAFKDAMEAIRQLQLDSVIQEEAQKGKPILGICLGMQLFYEQSLENGDWEGLGLLKGSIKRISGEVKVPHMGWNTLDIQQASPLFDSKLENPYVYFVHSYAVSSFEENTLLASSQYGQLIPAIVQKGNITGMQFHPEKSGEFGIELLKRYEEMIR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_STRPS
Sequence: MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETDGYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: AROC_STRZP
Sequence: MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RIMM_CAMC1
Sequence: MNSDIVEVATIGRCVGLKGYLKLHNKSDFPEQFKKGATFFDKNDDQLIIKDYNRQKELVLFEKFDDLDLAKTLVNKTIYTTKELTRKNCKLKKDEFFQFDIIGLKVVENGEILGIVEDIQDNFANSLLYIKTDEVLIAAGKPKNFYIPYLERFIESVNLDSGEILVKGARDILENS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGA_BUCAI
Sequence: MKITIYFFLLLLSFTINSVSATVQKFNFFDLNKQLNIFLKKEYPLNEDSIKIIIHTPLKKNIYCRKPDFSILSNTHNLGLINILLTCSKQHYYLTVEVQSEGEYIVANRKIPRGTRIKESDLKILIGRLDVLPNNTYRKKKDVVNRISLREFFPLQPITSFMTRPFWLVKVNQQVTVIINGNNFKMSSKAKSLSNGAQNQNIRVKTNSGKIINGIINENGEVIVSP
What is the function of this protein?
Involved in the assembly process of the P-ring formation.  It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly (By similarity).
What are the official names of this protein?
Flagella basal body P-ring formation protein FlgA.
What is the protein family that this protein belongs to?
Belongs to the FlgA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: METE_SHISS
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: Y2205_CLONN
Sequence: MYNFNKPIGSYGEHISENFLVSKGHKILTKNFRCRSGEIDIISSHNNYICFTEVKTRYNYSFGIPCESVTITKIKKIRNTAKFYIYINKLFKNNFKFNVIEIILNKYSNDYSINFIENAF
What are the official names of this protein?
UPF0102 protein NT01CX_2205.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RNC_FRATO
Sequence: MVPEYSRFYNILGYNFKDYTLLIRALTHRSKTKKNYERLEFLGDSVLSFVIAEVLYKQFTDLAEGKLSQLRSKLVKGTTLAQLASSLKMDEYIILGASEQGGHKREKILEDVFEAVIGAIYLDSDFATVKKVILKWYQPIISSINLDTIKFKDSKSKLQEILLQNALSLPEYSIETIDGKDHEQQFTVVAVSKDLNLRVKAQGTSRKKAEQKTAEKMIEMLSQQGLHEKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP27_SOLLC
Sequence: ELQLNYYTKSWXRAE
What are the official names of this protein?
35 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SFRP2_CANLF
Sequence: MPRGPGSLLLLVLASHCCLGSARGLFFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKLGGELVITSVKRWQKGQREFKRISRSIRKLQC
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types.  SFRP2 may be important for eye retinal development and for myogenesis.
What are the official names of this protein?
Secreted frizzled-related protein 2, sFRP-2.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CUER_SALTI
Sequence: MNISDVAKKTGLTSKAIRFYEEKGLVTPPLRSENGYRTYTQKHLNELTLLRQARQVGFNLEECGELVNLFNDPRRHSADVKKRTLEKVAEIERHISELQSMRDQLLAMAESCPGDDSADCPIIDNLSGCCHHKAQKLR
What is the function of this protein?
Regulates the transcription of the copA and cueO genes.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CueR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_HAHCH
Sequence: MAQKLFIKTYGCQMNEYDSSRMADLLGESHSVELTDNPDEADILLLNTCSIREKAQEKVFHQLGRWKTLKEKNPNLLIGVGGCVASQEGDAIRDRAPYVDMVFGPQTLHRLPEMVNSVAHQKIPMVDVTFPEIEKFDRLPMPSSEGASAFVSIMEGCSKYCTFCVVPYTRGEEVSRPVDDVIAEIAHLAGQGVREVNLLGQNVNAYRGLTHDGDYMDLAELITYVASVDGIDRIRYTTSHPVEFSDSLIDVYASVPKLVSHLHLPVQSGSDRILNLMKRGHTVAEYTDKLRRLQEIRPDISLSSDFIVGFPGETDADFEETMNLINEIGFDHSFSFVYSARPGTPAANLEDNVSEEAKKQRLAILQQRILQFAQDISRKMVGSTQRILVTGVSKKDPGELQGRTENNRVVNFRSDSHDIIGRFVDVTITAALPNSLRGERVDSLDY
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_PARPJ
Sequence: MVIIRLARGGSKKRPFYNIVATDSRNRRDGRFIERVGFYNPVATKGESLRIAQDRLTYWQGVGAQLSPTVERLVKEAAKAQPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y1413_XANCB
Sequence: MSVLPTPLANQLLIALPALSDPTFSRSVALICQHDENGAMGVLVNRPSEYTLGEVLSQMGIDTSDERLREQPVLSGGPVHPERGFVIHDDARAWDSSLEVGQGVYLTTSRDILEAMAAGDGPRNALVALGCAGWGAGQLEFELGENSWLTAPSDANVLFDTALEDRWQTAAGRIGVDLFRLTDYSGHA
What are the official names of this protein?
UPF0301 protein xcc-b100_1413.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RIMM_CORJK
Sequence: MELQIGRVIKPHGVRGEVVVDPTTDTPELRFATGEVLKGKQAGKELSLTVRSFRPHQGRLLVTFEEIADRTAAESLRGVRFFAAPVHDEDDDGFYDHELEGLTAYLLAPGTDLKGDEIQLGDLVGEVVAVEHTPAGQLLVILIDAESQLPTAGKEVLVPFRHQIVPVVDLEEEILVLTPPEGLLELS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRK1_ASCTR
Sequence: RPPGFSPFR
What is the function of this protein?
Induces relaxation of mouse trachea that has been precontracted with methacholine.  May induce relaxation of arterial smooth muscle.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Bradykinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIA_ECO45
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2386_SERP5
Sequence: MERFLENAMYASRWLLAPVYFGLSLALLALSIKFFQEIIHVLPNIFAIAEADLVLTLLSLIDMALVGGLLVMVMFSGYENFVSQLDISDDKEKLSWLGKMDSTSLKSKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDKLTRDKK
What are the official names of this protein?
UPF0114 protein Spro_2386.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.