PharMolix/UniProtQA huggingface dataset:
Protein: IF2_BURMS
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSETDKARLLDHLRKSHGATDGDKRKITLTRRHTSEIKQADATGKARTIQVEVRKKRTFVKRDDVSETGADQAQAQTDEQAEAELKRREEEARREAELLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAAQAEAAQQAAAAREQAQRAQSEPAEQSAQDEARAAAERAAQREAAKKAEDAAREAADKARAEQEEIRKRREAAEAEARAIREMMNTPRRAQVKAVEPPKPAEPPAAKAAEAKGTLHKPAKPAGEAAAARPAAKKPASGAPAPAAAPAGDRTKKPGTGKSGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGKHQDSASSFQAPTEPIVREVHVPETISVADLAHKMSIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGEIGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVESPAKGIVIEAKLDKGKGPVATVLVQSGTLSRGDVVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPGAGDEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGVVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVKQGFECGMSLKNFNDIVEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CK5P1_DICDI
Sequence: MINRLNRLCKKNILNNILNNNKNVSNRIINRFYCNLNTTNLKINNDNNLKESIREKIKDIPSLNEFLRNSNNEINENNENKSKIETEEEYELPPYLSSLPNDKGNGRKVWIETYGCQMNVSDEEVICSIMKSSGYTISNDFNTADIVFLNTCSIRENAEAKIWLRLTELRAIRRKQGRPNLIVGVLGCMAERLKEKLLESDMKVDIVVGPDAYRSLPSLLATLEDGEQQTAINVILSADETYADIKPVRKSDNQVSAYVSIMRGCNNMCSYCIVPFTRGRERSRPIDSILREVKDLSDQGFKEITLLGQNVNSFNYYEESNNNNNENFIDTQKNKLELESLKPREGFKTIYKSPKKGITFTKLMELVSKVDPEIRIRFTSPHPKDFPDDLLELIKNQPNICKQLHIPAQSGSSKVLESMRRGYTRESYIELIDTIKRVLPGCAISSDFISGFCGESDQDHNETISLMEYVGYENAFMFMYSLREKTHAHRQLKDDVPTTLKNSRLTQVVDTFYKRLKEKNQLEIGNHHLVLVDGFSKRSEKDFVGRTDTNKKVLISNDIENQDIKVGEYYIVEIIKGDSEVTLKGKPIMKSSIQHFNNIYNHKNKFI
What is the function of this protein?
Probable regulator of CDK5 activity.
What are the official names of this protein?
CDK5RAP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
Protein: NOSZ_STUST
Sequence: MSDKDSKNTPQVPEKLGLSRRGFLGASAVTGAAVAATALGGAVMTRESWAQAVKESKQKIHVGPGELDDYYGFWSGGHQGEVRVLGVPSMRELMRIPVFNVDSATGWGLTNESRHIMGDSAKFLNGDCHHPHISMTDGKYDGKYLFINDKANSRVARIRLDIMKCDKMITVPNVQAIHGLRLQKVPHTKYVFANAEFIIPHPNDGKVFDLQDENSYTMYNAIDAETMEMAFQVIVDGNLDNTDADYTGRFAAATCYNSEKAFDLGGMMRNERDWVVVFDIHAVEAAVKAGDFITLGDSKTPVLDGRKKDGKDSKFTRYVPVPKNPHGCNTSSDGKYFIAAGKLSPTCSMIAIDKLPDLFAGKLADPRDVIVGEPELGLGPLHTTFDGRGNAYTTLFIDSQVVKWNMEEAVRAYKGEKVNYIKQKLDVHYQPGHLHASLCETNEADGKWLVALSKFSKDRFLPVGPLHPENDQLIDISGDEMKLVHDGPTFAEPHDCIMARRDQIKTKKIWDRNDPFFAPTVEMAKKDGINLDTDNKVIRDGNKVRVYMTSMAPAFGVQEFTVKQGDEVTVTITNIDQIEDVSHGFVVVNHGVSMEISPQQTSSITFVADKPGLHWYYCSWFCHALHMEMVGRMMVEPA
What is the function of this protein?
Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
What are the official names of this protein?
Nitrous-oxide reductase, N(2)OR, N2O reductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
Protein: YOPT_YEREN
Sequence: MDSIHGHYHIQLSNYSAGENLQSATLTEGVIGAHRVKVETALSHSNRQKKLSATIKHNQSSRSMLDRKLTSDGKANQRSSFTFSMIMYRMIHFVLSTRVPAVRESVANYGGNINFKFAQTKGAFLHQIIKHSDTASGVCEALCAHWIWSHAQGQSLFDQLYVGGRKGKFQIDTLYSIKQLQIDGCKADVDQDEVTLDWFKKKGISERMIERHCLLRPVDVTGTTESEGPDQLLNAILDTHGIGYGYKKIYLSGQMSAHAIAAYVNEKSGVTFFDPNFGEFHFSDKEKFRKWFTNSFWENSMYHYPLGVGQRFSVLTFDSKEV
What is the function of this protein?
Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the human small GTPase RhoA/ARHA, a regulator of cytoskeleton.  Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell (By similarity).
What are the official names of this protein?
Cysteine protease YopT.
What is the protein family that this protein belongs to?
Belongs to the peptidase C58 family.
What are the subcellular locations of this protein?
Secreted. Note=In infected cells, it is cytoplasmic. Translocated into the host cell by the type III secretion apparatus with the help of the SycT chaperone.
Protein: GCH1L_PASMU
Sequence: MNALELEQILNHKLNSQAISDYAPNGLQVEGKKDIKKIITGVTASQALIEYAVSQNADAILVHHGYFWKSENPCIRGMKGKRIKTLLVNDINLYGYHLPLDVHPELGNNARLAALLEIEDLQPLEQGTVSIPVYGTLKTPLTSDAFAARIEQVLKRKPLVCSDNAPHLIRTVGICTGGGQSYIDLAANQGVDAFISGEVSEQTIHSAREQGIHFFAAGHHATERYGIKALGEWLSQHYDLEVEFKDIDNPA
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: GUAA_CITK8
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEENSPRAPEYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVRTNSALIRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTETCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVNRIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLTALKGENDPEAKRKIIGRVFVEVFDEEAFRLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CH60_ECOLU
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_ACCGE
Sequence: MVLSANDKTNVKNVFTKIGGHAEEYGAETLERMFTTYPPTKTYFPHFDLHHGSAQIKAHGKKVVGALIEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVAIHHPSVLTPEVHASLDKFLCAVGNVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: FDHD_STAA8
Sequence: MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATVICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRMIASCCGKSREFYFQNDAAIAKTSMSKITLTPMQIINMMTRLQSASHIYQETGGLHNAAISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGVGVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSMJL_METJA
Sequence: MTITQMISEILMHNTVYNYILSLISIILFIVIGKYANALIERLADKLHKKSGIELDELLIRALSLPVAIAIILSGFYFGVNFLYLLPSLKTAVNEGILTAFILCVVVFFDRFLNELVERYLALTISKKTKKDVDDQIVVLTKKLVRLVVWVVGLLLILSNLGYDIKTLLAGLGIGGLAVALASQNLVSNLIAGLIILTDKPFKIGNWITFSGGSGIVEDIGIRSTKIRATDNSIIVVPNSKLIDEIIQNVPSKNKWKVSTTIGVTYNTPVEKIRKAEEIIKNILLEHPNVEDEPITVYFKEFGDWSLNIQVVYYIKNSRYNGYQKYISTINEVNLKIKEEFDRKGIEFAFPTYTLYLKRDD
What is the function of this protein?
Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.  Selective for cations.  Rectifies with voltage.
What are the official names of this protein?
Large-conductance mechanosensitive channel MscMJLR.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_GLUOX
Sequence: MTAPQNGTGNGLQTGADLAVRSDSPLILALPKGRILKALAPVLTRTGIEPDPDCLTESSRRLRFGTSDPNLDVVRVRSFDVATFVAYGGADIGVCGADVLMEFDYPDIYAPLDLGIGGCRISVARPKTMVEDPATGQSRLCVATKYPTIARRHFASRAINAEIVHLNGAMELAPTLDLASVIVDLVDTGSTLRANGLMETETIAHVTSRLIVNRVALKTRPEEISALIERFRAALNTEEAA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH156_ORYSJ
Sequence: MEHHHLLLQLSPPPPPPPLPAAHLMMSPSFFDAGVFADVGGDWMEDLMHLGELFGVGVGGDDDDNGGVDGGVGGGDDRMQEWQNNCEGAGSPDHQPSCGDGDGDGDGDVSPRDGELGDGDGDNSATRKRRDRSKTIVSERKRRVRMKEKLYELRALVPNITKMDKASIIADAVVYVKDLQAHARKLKEEVAALEEARPIRPPPPSAAAQRPQRQPRRVAAAAAQLARAADAAAVTTAAAAPHGARVAHVGAAQVGEGRFFVTVECEPAAAAARGGGGGVAAPVCAAVESLSCFTVESSTVGCSPDRVVATLTLKVSEAEEDVSAISECTVKLWVMAALLKEGFRPQPTVQIS
What is the function of this protein?
Transcription factor involved in positive regulation of genes involved in strategy II iron acquisition, including genes for mugineic acid (MA) family phytosiderophores biosynthesis, and genes involved in S-adenosylmethionine cycle and iron transport (PubMed:31574173).  May play a role in the regulation of iron deficiency response by promoting the nuclear localization of IRO2 (PubMed:31574173).  Possesses transactivation activity in yeast (PubMed:31574173).
What are the official names of this protein?
Transcription factor BHLH156, Basic helix-loop-helix protein 156, OsbHLH156, bHLH transcription factor bHLH156.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7S_LEGPH
Sequence: MSKGIHFEQSITELEEIVRQLEKGELSLEESLKQFEKGISLARRCQNALNQAEQKIETLTGTDSNIELDSDEQTSD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNP1_PHANO
Sequence: MKFSAAVLGFASLASAISVSYDQGYDDAGRSLTSVSCSDGNNGLITKYGWQNQGAVAGFPRIGGYSGIAGWNSAQCGTCYGITYNGNTIYVLAVDHAGDGFNIAKQAMDQLTNGQAAGLGRIDANYQQVATSNCGL
What are the official names of this protein?
Protein SnodProt1.
What is the protein family that this protein belongs to?
Belongs to the cerato-platanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_LISMO
Sequence: MNPEQFQMALAEKGIELSDDQMKQFHDYFEMLVEWNEKMNLTAITDEKEVYLKHFYDSISAAFYVDFTKFDTICDVGAGAGFPSLPIKICFPHLKVSIVDSLKKRMTFLDALAEKLGLTDVHFYHDRAETFGQNKAHREKYDLVTARAVARMSVLSELCMPLVKKGGSFLVMKAAQAEQELQTAEKAIKLFGGKVEEHFSFSLPVEESERNIYVITKTKETPNKYPRKPGTPNKLPIE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA2_METCA
Sequence: MHVTPELAPVAKVGGLADVVFGLGRELEIRGNHVEIILPKYDCMRYDQIWGLQRTFDDLWVPWYGGAIHCSVYFGFVHGRKCFFIEPHSQDNFFNRGAVYGFHDDIFRFAFFSRAAMEFLWKAGKNPDIIHCHDWQTALVPVYLYEIYQPMGMRHPRVCFTIHNFKHQGVTGAQVLHASGLDRPEYYFHYDRLRDNHNPHAINLMKGGIVYANFVTTVSPRYAMEAKDQGQGFGLEPTLHIHHMKYGGVVNGIDYDVWNPEIDPHIPVHFNVDTIEGKYADKKALRDRLLLADNEKPIVSFVGRLDPQKGIELIRHALFYTLGQGGQFVLLGSSPDGAINGYFWGLKRQFNDNPDCHLEIGYNEELAHLVYAGSDVMVVPSRFEPCGLTQLIAMRYGTIPVVREIGGLADTVIDKDFSHRPLHERNGYVFRDYDERGLESALGRAIACYYQYPDHFRELMKNAMRYDYSWNHPGQDYLNIYHYIRDK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 2, Starch [bacterial glycogen] synthase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: HCP2_BPLP2
Sequence: MEFDSYIDWYNNLLTMPLNDVILGVKDTIEDKTVYLSLSDSKVIKMDNTSFVMGYYYQVVLSVKDVDDELVGLVGNVLQNGWNMTNWSENSHLYNYTGTVYLPCGAGGQAWQ
What is the function of this protein?
Probably functions as a stopper that is part of the head-tail connector and that locks the viral DNA in the capsid.  During assembly, functions as a docking platform which the preassembled tail can bind to.  Plays a role in morphogenesis of the virion capsid after genome packaging.
What are the official names of this protein?
Probable head completion protein 2, Connector protein gp9, Gene product 9, gp9, Stopper protein gp9.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus head completion protein 2 family.
What are the subcellular locations of this protein?
Virion. Note=Part of the connector between the portal and the tail.
Protein: 22P1_RAT
Sequence: MCKTLHGTLLLLAIFVLFLNFSHATAKRTRRGMEIFEKNFIDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIWGFGEIEMVKTKCRKIDSDFYKCSFQREFYNLKRTPGETMYYISLPGSVRCRKLLSKLDNCPFEEQTEQLKREICYFVVYPDYIEQNIHAVRFDCYTK
What are the official names of this protein?
Cystatin-related protein 1, CRP-1, Androgen-regulated 20 kDa protein, Prostatic 22 kDa glycoprotein P22K16/P22K20.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
Protein: Y154_NPVAC
Sequence: MDSSNCIKIDVKYDMPLHYQCDNNADKDVVNAYDTIDVDPNKRFIINHNHEQQQVNETNKQVVDKTFINDTATYNSCIIKI
What are the official names of this protein?
Uncharacterized 9.4 kDa protein in PE38 3'region.
Protein: NUOD2_ANADE
Sequence: MEKLILRRVDRQNEEMILNFGPQHPSTHGVINFLVETDGEVLKRATPDVGYLHRSIEKIGELVGYPGFMPYTDRVDYVAAMFANEGYAIAVERLLKIEVPQRAQWLRAISCELCRIASHLVSVGTMVMDIGAFTPMLHGIRERETINDLLEALCGARLTYNYHRIGGVAFDLPEGWRDKVLHFLDHFDKFLAEFDRLISFNEIYVKRLANVAVIPGPMAINYGLVGPNLRGSGVDWDVRRDLPYGAYPNFKFDVPVGKGFFGTAGDSFDRYYVRCLEMAESSKIVRQALDSLPEGEITAKVPRNIKPEAGEALGRVESARGELAYYVISDGTNKAYRVRARTGSFTAMCIIEDISRGLMVADLVALISSLDVVAPEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUOH_PARP8
Sequence: MTLFESINAGGTQILGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKEVIQPTQASRWVYLVAPVMVVVPAFAVWAVIPFQAGAVLGDINAGLLYAISISSVGVYGVILAGWASNSKYAFLGAMRAAAQMVSYEVSMGFALVVVMMTAGTMNLSDIVGSQMRGIFASHGVTFLSWNWLPLLPAFVVYFVSGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALASILFLGGWSAPFEFLSFIPGIVWLVLKVFLLLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVIWVVVVGFWIMSPLNIWN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ICP22_SHV21
Sequence: MAPRRRKAKRRRHTLRSECKDKCKCHVQCYVSPRKRRRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKMQPQHRSRLPKGKQSHDKVPKKYQARNKFFSQAAPSVLDLSPKSWCWVVDFWGPTDALYRLSRSLSFPGAVSSGIQTFPKGPHATGPWVYFITVYCRTFQTAKEVIKAQKKYEKKYPRSAKLKASLGKFSKSLPIE
What are the official names of this protein?
Transcriptional regulator ICP22 homolog, Immediate-early protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP22 family.
Protein: YAE1_ASPFU
Sequence: MTSPQTNSLDDIFGSSPPHEGEKFSQQASIEAPEPSDLPSLRRQHVTAGYRDGVSAAKGEHVQHGFDAGFPIGAQLGMRAGTVIGIIEGLLRGFESPTASRAVKKPLQRKEEGQGVETDEAEAARQAKREQLLRLYQKAVKELEVRSVFAGSEEESTRDNGGQEKPEVVLRRKGDAVISQWEEQVRVAHWEENMAALEPKEDEKRASTPTEQI
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein yae1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCR3_CANLF
Sequence: MEATTAEIKTMDESIQTTVFDYENSLPCEKVNIKHLGAQFLPPLYSLVFVIGLLGNVVVVVILTKYKRLWIMTNIFLLNLAISDLLFLFTLVFWIHYTGWNDWVFGRSMCKLISGLYYLGLYGEIFFIILLTIDRYLAIVHAVFALRARTVTFGIITSVLTWGLAGLAALPEFIFHESQKESEQFVCTPLYPKDQEDNWKRFHALRMNILGLALPLLIMVVCYSGIIKTLLRCPSKKKYKAIRLIFVIMVVFFIFWTPYNLVLLLSAFQTIFFETTCEQSKQLDVAMQITEVIAYTHCCINPIIYAFVGERFRKHLCHFFRRNVATYLGKYIPFLPSEKLERSSSVSPSTGEQEFSFVF
What is the function of this protein?
Receptor for C-C type chemokine.  Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15.  Subsequently transduces a signal by increasing the intracellular calcium ions level.  In addition acts as a possible functional receptor for NARS1.
What are the official names of this protein?
C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METE_NEIM0
Sequence: MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQAAANADYVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKGAVEFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALTVDLPKEWVEAYKDVYATLSKVSAKILLGTYFGSVAEHAALLKALPVDGLHIDLVRAPEQPDAFADYDKVLSVGVIDGRNIWRANLNKVLETVEPLQAKLGERLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFVNRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAADYEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRATVCKQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLTAFGKFKYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLRAELAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: TLBP_THET8
Sequence: MKRVSRRAFLRRLGVGVAATAAFSPLAVAQARRYRWRIQTAWDAGTVGYSLFQKFTERVKELTDGQLEVQPFPAGAVVGTFDMFDAVKTGVLDGMNPFTLYWAGRMPVTAFLSSYALGLDRPDQWETWFYSLGGLDIARRAFAEQGLFYVGPVQHDLNIIHSKKPIRRFEDFKGVKLRVPGGMIAEVFAAAGASTVLLPGGEVYPALERGVIDAADFVGPAVNYNLGFHQVAKYIIMGPPETPAIHQPVDLMDFTINLNRWRSLPKPLQERFIAAVHEYSWIHYAGIQKANLEAWPKYRQAGVEVIRLSNEDVRKFRRLAIPIWFKWAKMDKYSREAFASQLEYMKGIGYVTDEELKGLSL
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system involved in the uptake of lactate.  This protein specifically binds L-lactate.
What are the official names of this protein?
Lactate-binding periplasmic protein TTHA0766, ABC transporter, solute-binding protein, Extracytoplasmic solute receptor protein TTHA0766, TRAP transporter lactate-binding subunit P.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPXD_COXBN
Sequence: MTRGLTYSLTELATAIGATVQGDGDCKIHNVAAIAQAQPGEISFVTDRKYRKYLTQTKASAILLDEKLASRCPINALVMSNPKLGFAKLLTLLRPQSLPTGGIHPTAVVGANCQIDPSAHIGAHVVIEEDVVIGPRTLIGAGASIGRGSQIGSDCCLHSRVTLYSQTRIGDRSIIHSGAVIGADGFGLIQDEKGEWVKIPQVGRVIIGDDVEIGANATIDRGALDDTVIGNGVKIDDLVMIAHNVRIGDHTVIAGCAGVAGSTTVGRHCMIGASAGLNGHIEICDNVIITGMGMIQKSITKPGIYSSGTGMQTNREWRKSVIRFWQLDELAKRLKRLEKLIR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: EX3_HAEIN
Sequence: MKFISFNINGLRARPHQLEAIIEKYQPDVIGLQEIKVADEAFPYEITENLGYHVFHHGQKGHYGVALLTKQEPKVIRRGFPTDNEDAQKRIIMADLETEFGLLTVINGYFPQGESRAHETKFPAKEKFYADLQQYLEKEHDKSNPILIMGDMNISPSDLDIGIGDENRKRWLRTGKCSFLPEERAWYQRLYDYGLEDSFRKLNPTANDKFSWFDYRSKGFDDNRGLRIDHILVSQKLAERCVDVGIALDIRAMEKPSDHAPIWAEFK
What is the function of this protein?
Major apurinic-apyrimidinic endonuclease of E. coli.  It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction (By similarity).
What are the official names of this protein?
Exodeoxyribonuclease III, EXO III, Exonuclease III.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.