PharMolix/UniProtQA huggingface dataset:
Protein: DESM_CANLF
Sequence: MSQAYSSSQRVSSYRRTFGGAGGFPLGSPLGSPVFPRAGFGTKGSSSSVTSRVYQVSRTSGGAGGLGALRAGRLGTGRAPSYSAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAEIYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMREMEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
What is the function of this protein?
Muscle-specific type III intermediate filament essential for proper muscular structure and function.  Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.  In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.  May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.  Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult.  Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin.
What are the official names of this protein?
Desmin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Nucleus. Note=Localizes in the intercalated disks which occur at the Z line of cardiomyocytes. Localizes in the nucleus exclusively in differentiating cardiac progenitor cells and premature cardiomyocytes.
Protein: RIBBA_BACAN
Sequence: MFHRIEEALEDLKQGKVVIVCDDENRENEGDFIALAEYITPETINFMITHGRGLVCVPITEGYAERLQLEPMVSHNTDSHHTAFTVSIDHVSTTTGISAHERATTIQQLLNPASKGADFNRPGHIFPLIAKEGGVLRRAGHTEAAVDLAQLCGAEPAGVICEIINEDGTMARVPDLLQCAKQFDIKMITIEDLIAYRRHHETLVTREVEITLPTDFGTFQAIGYSNSLDTKEHIALVKGDISTGEPVLVRVHSECLTGDVFGSCRCDCGPQLHAALAQIEREGKGVLLYMRQEGRGIGLLNKLRAYKLQEEGFDTVEANEKLGFPADLRDYGIGAQILKDLGLQHLRLLTNNPRKIAGLQGYDLTVTERVPLQMPAKEENKTYLQTKVNKLGHLLNL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: UBIA_XANAC
Sequence: MSKHGVEQLPAARALTWPQRLGQYWKLVRGDRPIGSLLLLWPTWWALWLAADGLPPLWTLFVFTAGVWLTRSAGCVINDYADRWLDPHVERTKSRPLATGAVSGREALWVFVALMLVAFALVLTLNWLTVMLSVPGVFLAASYPYLKRHTHLPQVYLGMAFGWGIPMAFAAVQGSVPLLGWLLYAANILWATAYDTWYAMVDRDDDIRMGSKSTAILFGRFDLIAQGILYALMAATLVMVGLRADLGAAYWAGLGAAALLVAYEFRIARHRERGPCFRAFLHNNWVGLAIFVGIAVAVAGR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DUT_CAMPS
Sequence: MFNMNINSPVRFVKETNRAKSPTRQSPYAAGYDLYSAYYYTIPPGERQLIKTDISMSMPKFCYGRIAPRSGLSLKGIDIGGGVIDEDYRGNIGVILINNGKCTFNVNTGDRIAQLIYQRIYYPELKEVQSLDSTDRGDQGFGSTGLR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RGI1_LODEL
Sequence: MSGKKKSKSDTVPLDLDNIKPLDHLQAVPKTRKMSMTSIESADEPGGFKEVLLPPTIKEFDELEQFEAFVRDETWDNDFDYFHGRLHYYPPFVLKECHDEIEKIKPTSNKNSSKFKRNLQHHIKKHLIKDLEKCCGYELNFDKAEEIESFDKLTWKFKDETDHGFSKEEEDKYDRHWKIELDITSHNDSALVDIDMKSIPIGH
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNH2_GEOUR
Sequence: MKTLNLFPCEERPSLLEFESLVRRQGYACIAGIDEAGRGPLAGPVVAAAVILPNGVELPGVNDSKKLSPVKRNELFDLIMASASAVGVGSSDAGLIDEINILQATLAAMKQAVSMLCIPPDYLLIDGISKVPLSIPQKTIKKGDSLSLSIAAASIIAKVSRDRLMMDYETRFPGYGFAAHKGYGCVSHMAAIAELGPCAIHRKTFRGVKEYVRSEE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ACIAC
Sequence: MQLELLNDQGQAASKIDVPETVFDRQYNEDLIHQIVVAYRANARQGTRAQKDREQVRHSTKKPFKQKGTGNARAGMTSSPLWRGGGRIFPNLPEENFTQKINKKMYRAGMASILSQLAREGRLAVVDSLKVETPKTKVLADKFKAMNLQSVMVISDEVDENLYLASRNLKNVFVVEPRYADPVSLVHYKKVLVTKGAIDKLKEMFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KTHY_WOLPM
Sequence: MFITFEGIDGSGKTTQSKLLANHFKQIRGENNVVLTREPGGTNFAEKVRGVLLTNNIDSISELLLLISMRREHMKKLILPALAEGKIVICDRFIDSTIAYQGYGFGVDLRLIRDLHKLVEIKYPDITFILDIDVKVGLNRAKDKNKYEEMDVNFYNKVRKGFQEIAIKEPVRCSVITGIETKNDNHVHNEIIDKIT
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TYSY_BRUA2
Sequence: MRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKENGVTIWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANLLKMLHTNPQSRRLIVSAWNPALVDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX38_TITSE
Sequence: MKHLKFYSILFLFSIFVYKVNALQKILDGYFLSDEEGLFLSCKHKFDEYFCLEKCVESGAKDGYCVGHSFICFCKYEVGSSPRHFMF
What is the function of this protein?
Putative sodium channel toxin.
What are the official names of this protein?
Putative sodium channel toxin Ts38, Tityustoxin-38.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: VPC39_MYCTU
Sequence: MTALLDVNVLIALGWPNHVHHAAAQRWFTQFSSNGWATTPITEAGYVRISSNRSVMQVSTTPAIAIAQLAAMTSLAGHTFWPDDVPLIVGSAGDRDAVSNHRRVTDCHLIALAARYGGRLVTFDAALADSASAGLVEVL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB39.
What are the official names of this protein?
Ribonuclease VapC39, RNase VapC39, Toxin VapC39.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
What are the subcellular locations of this protein?
Secreted. Note=Following 6 weeks of nutrient starvation.
Protein: K2013_BOVIN
Sequence: MWLQQRLKGLPGLLSSSWARRLLCLLGLLVLLLWFAGSGARRAAGGLQLLPWPHGEPGAAEPSACLEAATHAWRSLRERGEAVLLGPGVPSLVANGFLALDVVANRLWVTPGEREPAVAPDFVPFVQLRPLSALPEAGESVLLLREGLLRRVRCLQLGTSGPGPAAAGPGPASASGLLTGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPAPRAFTSTLEKVGDHQFLLYSGRSPPVPTGLVHLVVVAAKKLVDRLQVAPRTQLDETVLWVVHVSGPLNPQVLKSKAAKELKVLQDLARKEMLELLEMPAAELLQDHQRLWAQLFSPGVEMKKITDAHTPSGLTVNLTLYYMLSCSPAPLLSPDLSHRERDQMESTLNYEDHCFSGHATMHAENLWPGRLSSVQQILQLWDLWRLTLQKRGCKGLVRAGAPGILQGMVLSFGGLQFTENHLQFQADPDVLHNSYALHGIRYKNDHINLAVLADAEGKPYLHVSVESRGQLVKIYACEAGCLDEPVELTSAPQGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPFFRNKEDPSV
What are the official names of this protein?
Uncharacterized protein KIAA2013 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MNTP_DESDA
Sequence: MTIFAVFLLAIALSMDAFAVAVVSGCALQKPKVCHYVRLSAAFGFFQFAMPVIGWWLGVSVREYMEAWDHWIAFVLLGWIGGKMALSGLRALRNRESCACPSVDPTAGRNLVVLGVATSIDALAVGLSLAILGTPIWADAAIIGIVCAVITACGVYLGKTLANLCALNGWAELAGGLTLLAIACNILREHQVF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XNI_SHISS
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: VIRC2_AGRRH
Sequence: MGIRKPALSVGEARRLAAARPEMVQAHLPVATQNSALPQPPENPDQEDRRPAPAVAKRHPSADRQSMLTVDALSSTTAPEKIQVFLSARPPAPQVSKIYDNLILQYSPSKSLQMILRRALGDFEKMLADGSFRTAPKSYPIPQTASEKSIIVQTSRMFPVPLLEVARNHFDPLGLETARAFGHKLATAALASFFAGEKTTKR
What are the official names of this protein?
Protein virC2.
Protein: YVDD_VACCW
Sequence: MIVAWFLLLILLEKHGLPMTQGSVNFLILSDLIFFDPLQAKSGSSLQNTDLFKCMLAINGLGPLSNTSVKIV
What are the official names of this protein?
Uncharacterized 7.9 kDa protein.
Protein: YIDC_GLAP5
Sequence: MNSNRSLLIMGLLLVSFLIFTQWQQDYNPEIQAQKQAMAQAQTQQVANQSSDVPASSNAASINEQSTKGKTITIETDVLRLTVDTLGGDVVDSDLLKYNAELDSNTPFELLQDNGKVLYVAQSGLVGKNGIDTTAGRAQYQATAEKFALAEGQDEIALPLTFEKDGVVYTKTFTLKRGSYNVAVNYHIKNGTAETLEVQPYGQLKHTLVESTGNFAMPTYTGGAYSSSEVNYKKYSFDEMAKANLSVDTKAGWAAVLQHYFVSAWIPNQDAENNLYTRTGNGVGTIGYRGPVTQVAPNGEATITSHLWTGPKDQAAMAQVANNFDLTVDYGWAWFIAKPLFWLLTFIQSIVSNWGLAIIGVTIVVKTILYPLTKAQYTSMAKMRMLQPRIQEMRERFGDDRQRMSQEMMKLYKEEKVNPMGGCLPILLQMPIFIALYWTFMEAVELRHAPFFGWIQDLSAQDPYYIFPLLMGGSMYLLQKMSPTPIADPVQQKVMNFMPVMFTVFFLWFPSGLVLYWLTSNLITIAQQWLIYRNLEKKGLHTRVKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SFSA_ALKCK
Sequence: MRLPPLTKMQFVHRPNRFVVELKRTDTEENVLAHLPDPGRLRELLVEGAIIWAEPAVDPLRKTAWTAVLCETPGGDLVSLKTTFANQLVEEALASQSLEAFSGWQLEKREATIGQSRFDFLLSKNGRTLVLEVKSVTLARGSKGFFPDAVTKRGAKHVRELTALNLLPEYESAVLFVSQHSNISTVEMESSIDADFAKAIKEANDKGVFISAVSTELSKQNICLKNRIPVVV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RL35_GEOSE
Sequence: MPKMKTHRGSAKRFKKTASGKLKRGHAYTSHLFANKTKKQKRHLRKATLVSPGDFKRIRQMLDNLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AHLL_BACCE
Sequence: MTVKKLYFVPAGRCMLDRSSVNSTLTPGNLLNLPVWCYLLETEEGPILVDTGMPESAVHNENLFEGTFAEGQILPKMTEEDRIVTILKRVGYKPEDLLYIISSHLHFDHAGGNGAFSNTPIIIQRAEYEAAQYREEYLKECILPNLNYKIIEGDYEVVPGVQLLYTPGHSPGHQSLLIETEKSGLVLLTIDASYTKENFEDEVPFAGFDSELALSSIKRLKEVVMKEKPIVFFGHDIEQEKGCKVFPEYI
What are the official names of this protein?
N-acyl homoserine lactonase, AHL-lactonase, Quorum-quenching N-acyl-homoserine lactonase.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: Y1179_STAHJ
Sequence: MNVFQIRDKLKQRLAHLNVDFKFDREEETLRIYRQDNYKGVTIKLNAIVAKYEVQKEKIIDEIVYYVEEAIAQMDDESIEKMTNIQIMPVIRATSFDKKTKEGHRFIIEKHTAETNIYYALDLGKSYRLIDESMLESLGLTEQQVKEMSLFNIRKLKNEYKTDEVKGNIFYFVNSNDGYDASRILNTKFLDDIYQQCEGEMLVAVPHQDVLVIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYEKGHFEPIFILGKNNKQKRDSNVIQRLEANRKRFNNKK
What are the official names of this protein?
UPF0354 protein SH1179.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: TRUA2_BACCR
Sequence: MHNYKLTIQYDGARFKGWQRLGNNDNTIQGKIESVISEMVGKEIEIIGCSRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHDRFHARYNSKAKTYLYKIWNEEHTNPFMRKYSMHVNKKLNVKSMKAAAKHLVGSHDFTAFSNAKSKKKSMVREVYTLDVMEEAGFVQIRVSGNGFLHNMVRKIVGALIEVGLGQLDAEAIPNILEEKQRNQINCLAEASGLYLENVEF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 2, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 2, tRNA-uridine isomerase I 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PYRE_GLAP5
Sequence: MQQYKHDFIEFALSRNVLKFGEFTLKSGRQSPYFFNAGLFNTGRDLAKLGEYYAKAIQASQIDYDVLFGPAYKGIPIATTVAVALANQFDVDKPCCFNRKEVKDHGEGGNLIGSPLKGRVLLVDDVITAGTAIRESMEIIQANNATLAGVMIALNRKEKGKSELSAIQEVERDYGCQVFSIIDFDDLVSFLERSAQYTDYLPKMREYREKYGIK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MANA_ASPFN
Sequence: MKLNPSLLTAAGLVSAQLASALPQASSSTVSPSPSPSATPGSFVTTSGLNFVIDGKTGYFAGSNSYWIGFQKNNDDVDLVFSHLQESGLKILRVWGFNDVNQKPTDGSVYYHLLADGTATVNEGEDGLQRLDYVVSSAEKHGIKLIINFVNFWDDYGGINAYVKAFGGSKEDFYTNDAMQAAYRAYIKAVISRYSDSTAIFAWELANEPRCQGCETTVLYNWIESTSQYIKSLDSKHLVCIGDEGFGLDTGSDGSYPYQYSEGSDFAKNLAIPTIDFGTFHLYPSSWGTTNDWGNGWVTSHGAACKEAGKPCLFEEYGVTSDHCAVEKPWQNTALNTTAISGDLYWQYGDQLSGGPSPDDGNTFYYGTDDFKCLVTDHIAAINSRN
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase A, Endo-beta-1,4-mannanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN513_MOUSE
Sequence: MPRRKQSHPQPVKCEGVKVDTEDSFDEGPGALVLESDLLLGQDLEFEEEEEEDEGDGHNDQLMGFERDSEGDSQGARPGLPYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPPLPPRLLYSCRLCAFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHTGPPTPPCPTCGFRCCAPRPTRPPSPTEQEGTMPRRSEDALILPDLSLHVPPGGASFLPDCGQLRGEGESLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGVATGGPQGPGDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSAPEGWAPPHSPPSVLSTRGPAALGATGSRALHSDSP
What is the function of this protein?
Transcriptional regulator that plays a role in retinal development and maintenance.
What are the official names of this protein?
Zinc finger protein 513.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_CARHZ
Sequence: MPKIKTKKAAAKRFKKTGSGKVKHFHAFHSHLLGHKTSKRKRRLRKSAIVSKGDMKIIKKILPY
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SHE3_YEAS8
Sequence: MSDQDNTQTSSSKLAPHHNIFMANLESSPTKDRNTSSQNASSSRVIESLHDQIDMLTKTNLQLTTQSQNLLSKLELAQSKESKLLENLNLLKNENENLNSIFERKNKKLKELEKDYSELSNRYNEQKEKMDQLSKLAKNSSAIEQSCSEKLQNMEVNYNSLLESQNLYRDHYSDEISKLNEKIGLLELELSNQNLNYGSDTSSNSDIELNLNKFNDSVKDLKSLETEKDSKLSKIITHSLDELNLQSWLNLYQTNENLISTFAEKMDLKDVLKRNDEKISNKGAVVQTLKKNVQTQVESNNADALSSNNAQDMLPIKMVKLRKTPNTNDSSSNGNSSNNKRRSFYTASPLLSSGSIPKSASPVLPGVKRTASVRKPSSSSSKTNVTHNNDPSTSPTISVPPGVTRTVSSTHKKKRNSMVVHGAQS
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 3.
What is the protein family that this protein belongs to?
Belongs to the SHE3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CP51_MYCBO
Sequence: MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLHNAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVLIAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPACVRYRRRTGV
What is the function of this protein?
Sterol 14alpha-demethylase whose physiological substrate is not known.  Accepts electrons from the iron-sulfur ferredoxin Fdx encoded by an adjacent gene.  In vitro, catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol, to produce the 8,14-dienes stereoselectively.
What are the official names of this protein?
Sterol 14alpha-demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHY_HORSE
Sequence: MMSAKNMVKVMIVMFAIFLLAKSDGKPVRKRSVSEIQLMHNLGKHLNSVERVEWLRKKLQDVHNFIALGAPIFHRDGGSQRPRKKEDNVLIESHQKSLGEADKADVDVLSKTKSQ
What is the function of this protein?
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.  Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).
What are the official names of this protein?
Parathyroid hormone, PTH, Parathyrin.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_MYCUA
Sequence: MAAQSKQAKPSGKQGGKKIIATNRKARHNYSIIEVFEAGVALQGTEVKSLRERHASLVDAFATVDDGEVWLRNLHIPEYLHGTWTNHEPRRNRKLLLHRRQIDTLFGKIREGNFALVPLSMYFLDGKVKVELALARGKHAHDKRQDLARRDAQREVIRELGRRAKGMG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MIAA_BARHE
Sequence: MKGRTITLIAGPTASGKSALALQIAQEKNALIINTDSMQVYDVLNILTARPTRTDTATVPHYLYGYVNPALHYSVGQWLCDVSKLLMTFTSKSLIFVGGTGLYFRALLEGISKIPDIPDVVRQKWRLRLDKEGAENLYRQLWQVDAVLAEKISSQDGQRIVRALEVYDATDKKLSWWQKKKTTPLIARNCSEKLLLIPPRQLLYERIHKRLDSMIEKGALEEVIAMKKLALSPLLPAMKAIGIPEFIAYLDGKQSFEEALEMVKTQTRRYAKRQITWFRNQFDEEWMLLS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CITG2_SALPA
Sequence: MMPIPANPTNASIQPRSLYDAWADLAWRAMLTEVNLSPKPGLVDRLNCGAHKDMALADFHRSAEAIRHWLPRFMEYGASCTRLPPESVLAGLRPLGMACEAAMFRATAGVNTHKGSIFSLGLLCAAIGRLYQLRQPIAAETLCATAADFCRGLTTRELRQNNLLLTAGQRLYQQQGLTGARGEAEAGYPLVIRHALPHYRALLAQGRDPDLALLDTLLLLMSLNGDTNVASRGGADGLRWLQQHAAFLLHQGGIRTPDDLVYLHRFDQQCIERNLSPGGSADLLIVTWFLAQISQVNH
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 2, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.