PharMolix/UniProtQA huggingface dataset:
Protein: PAR10_MOUSE
Sequence: MAEVEAGAALELRGLPPEIPDELITLYFENHRRSGGGLLLSWQRLGCGGVLIFQDPADAKRVLAQAEHRLHGVRLSLRPAPPRAPERVLLQHLPPGTSPLSLEQHVQALLGAAGHPVQTCHALASPRQDCALVQLSTPLSEAEVSALAEQARNLPLNGATVSLAWVPQTRAVRVVDSASPVDLLLLELYLENERRSGGGPLEGLRSLPGQLGTVISFQQWQVAERVLKQKHWLQGIELSLVPHYDVLEPEALAEGVSGRDHSATQESGVIGHAPTGTGGLAGALTMAVGSGEAPQQLGTLLRAGPVGAPGQALPVDSGSIRIQGSMGSTSPVDPVESSTELPEQVGPMASDSVGVQEQEGLGEVATGQEGLMGLVGTAMESVETGLESPGYGEMQKQEGLVEMVMSVEPGAVRYLQLYYEDLLASLEDVALFPLEGTDVTGFRLCGARAPCQAAQELLQSLLGSISCHTLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLASATLDIDPERTDPTEALQVLHGHITGIDQESLRLEDVRELLATLESPHGGEDRVPLEMEKEKPGGPGETVVEQQEEIPTLEAEEEPVALSTGARGQLEEEATLQLAIHRSLESQSQVADQQEANALRRAMALSLLEAEEALDEDTGGEAQLVVHTSFEQDVDELNQALSNALEAHLREETVSLQGRMLPPELGARLERCHDVSATLRGDRVVLRGFGVQPARAARHLAALLVDPWDQNLTFPLEASKPNLSEQGLKEPLGRLEALEENSQEFQDVVRAFYSTLDAVHGRIRIVRVERVSHPLLQQQYQLHRERLMQSCQQRPVEQVLYHGTSESAVLDICAHGFNRSFCGRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGYKAVFVAQVLTGDYGQGSRGLKAPPLRVSGQVLRYDSAVDCLQQPRIFVIFHDTQALPTHLITCKNILPGTP
What is the function of this protein?
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate and aspartate residues on target proteins.  In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation.  Catalyzes mono-ADP-ribosylation of GSK3B, leading to negatively regulate GSK3B kinase activity.  Involved in translesion DNA synthesis in response to DNA damage via its interaction with PCNA.
What are the official names of this protein?
Protein mono-ADP-ribosyltransferase PARP10, ADP-ribosyltransferase diphtheria toxin-like 10, ARTD10, Poly [ADP-ribose] polymerase 10, PARP-10.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1- dependent manner.
Protein: SCAF_SHV21
Sequence: MSIVYVAGFVDVVAYPKVDPVLYLNLDDVSKCLPLTKPIPLNIEHLPESTIGHTIGLYAVTHGVFCVGVIHSEKFLHLTENLFSNSCVAQATSKFLPYQPLLEMLHTWLPALSLSSLCPTAQNAANTNMFQHVSLCALGRRRGTVAVYSMNLEDAISQFCSISQAEVENIYQDSKNVDINSLPKPVFNIDPHILMAKAIDAGFIKDRLQLLKTDKGVAKIKKLTYLKASEIGKPVTEDISEDMNQHGIVPQGSDDLISVPKSTFLSMLQNNLDNFKQHPRPACFPQYFSPQGAYMPYELYPPQPYSGDNIGYMLPSGSYVPAMFPSRPNKRKREDFDDCVFPGESSLYKDVLNLTKNISQLQDDLKDLKQAAINQPNRYPPHHFSNPYSLDPGHASYFRYAPYGAPKPDQHLLQPLACVQQAPVVQPNYAPPPTEGASNEAPKPSVQEPVHIDASFAQDPVSKLQKMFCDELLNK
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: NK1R_RAT
Sequence: MDNVLPMDSDLFPNISTNTSESNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAHKRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQSSVYKVSRLETTISTVVGAHEEEPEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide substance P.  It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
What are the official names of this protein?
Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCR1_SCHPO
Sequence: MTAKKKEVDDEKRRRILERNRIAASKFRQKKKEWIKELEQTANAAFEQSKRLQLLLSQLQQEAFRLKSQLLAHQGCQCSVKIRSVLTDFQTAHNALHSQHMAYRPVQPPPGDNMLESVVSVSPTQMHPSLQGLPPNQHPQMPPSSQQPNSDDVQQHMFSAAGLPRSLGGPI
What is the function of this protein?
Involved in regulation of gene expression for sexual development (PubMed:8552099).  Binds and activates CRE sites (cAMP-response elements, also known as M26 meiotic recombination hotspots) (PubMed:8552099, PubMed:7958849).
What are the official names of this protein?
Transcription factor pcr1, Transcription factor mts2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPS1_ARATH
Sequence: METAICGRLALAPSSLFNSKSGDKHLVSKGPCVNRSILMTLSTSAALGKGGGVLDKPIIEKTTPGRESEFDLRKSKKIAPPYRVILHNDNFNKREYVVQVLMKVIPGMTVDNAVNIMQEAHINGLAVVIVCAQADAEQHCMQLRGNGLLSSVEPDGGGC
What is the function of this protein?
Small adapter protein that modulate the activity of CLPC (By similarity).  Involved in plastid biogenesis in particular when chloroplast protein synthesis capacity is a limiting factor (PubMed:23898032).  Probably involved in substrate selection for plastid Clp protease system (PubMed:23898032).  Recruitment to ClpC chaperones is facilitated by CLPF thus forming a binary adapter for selective substrate recognition and delivery to plastid Clp protease system (CLPC) (PubMed:26419670).
What are the official names of this protein?
ATP-dependent Clp protease adapter protein CLPS1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: AHL15_ARATH
Sequence: MANPWWVGNVAIGGVESPVTSSAPSLHHRNSNNNNPPTMTRSDPRLDHDFTTNNSGSPNTQTQSQEEQNSRDEQPAVEPGSGSGSTGRRPRGRPPGSKNKPKSPVVVTKESPNSLQSHVLEIATGADVAESLNAFARRRGRGVSVLSGSGLVTNVTLRQPAASGGVVSLRGQFEILSMCGAFLPTSGSPAAAAGLTIYLAGAQGQVVGGGVAGPLIASGPVIVIAATFCNATYERLPIEEEQQQEQPLQLEDGKKQKEENDDNESGNNGNEGSMQPPMYNMPPNFIPNGHQMAQHDVYWGGPPPRAPPSY
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity).  Binds the DNA sequence GNFEI (GA-negative feedback element I) in the GA3OX1 promoter (PubMed:17277098).  Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered FRK1 expression (PubMed:20738724).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 15, AT-hook protein of GA feedback 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEP_HAEIN
Sequence: MSNLFFVILLAVGFGVWKVLDYFQLPNTFSILLLILTALSGVLWCYHRFVVLPKRHRQVARAEQRSGKTLSEEEKAKIEPISEASEFLSSLFPVLAVVFLVRSFLFEPFQIPSGSMESTLRVGDFLVVNKYAYGVKDPIFQNTIIAGEKPQRGDVIVFKAPQQALIRTGLGATRAAFAENLALSSKDNMSGVDYIKRIVGKGGDRVIFDVEQKTLKVVYGKEGKPCEIDCETKAFEYTQNPTNPAFPNELELTEKGDVTHNVLISEYRRYSDLEFFPQEGMQTAEWLVPEGQYFVMGDHRDHSDDSRFWGFVPEKNIVGKATYIWMSLEKEANEWPTGFRFERFFTAIK
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1089_LIMRJ
Sequence: MEIEKNYRINSLFEFYQPLLTKKQNDYLELYYGDDYSLGEIAENFHVSRQAVYDNIKRTESILEDYEAKLHLYAEFQVRNQQADRIQRYVRENYPDDATLNHLVNHLESLEEE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein LAR_1089.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: PPSA_PYRFU
Sequence: MAYRFIKWFEELSKNDVPLVGGKGANLGEMTNAGIPVPPGFCVTAEAYKYFVENVKVSKEDVKRILGEKVNKGTISEVLAQAPDEPRPLQDWIMDIISKTDVDDSKMLQENTEAIRTLIKSLDMPSEIAEEIKQAYKELSQRFGQEEVYVAVRSSATAEDLPEASFAGQQETYLDVLGADDVIDKVKRCWASLWTARATFYRAKQGFDHSKVYLSAVVQKMVNSEKSGVMFTANPVTNNRNEIMINASWGLGEAVVSGAVTPDEYIVEKGTWKIKEKVIAKKEVMVIRNPETGRGTVMVKVAEYLGPEWVEKQVLTDEQIIEVAKMGQKIEDHYGWPQDIEWAYDKDDGKLYIVQSRPITTLKEEATAEEAEEVEEAEVILKGLGASPGIGAGRVVVIFDASEIDKVKEGDILVTTMTNPDMVPAMKRAAAIVTDEGGRTSHAAIVSRELGIPCVVGTKEATKKLKTGMYVTVDGTRGLVYKGIVKSLVKKKEEAKAEGGQVVVAGAPLVTGTMVKVNVSMPEVAERAAATGADGVGLLRAEHMILSIGQHPIKFIKEGKEEELVEKLAEGIEKVAAAFYPRPVWYRTLDAPTNEFREMPGGEDEPEERNPMLGWRGIRRGLDQPELLRAEFKAIKKVVEKGYNNIGVMLPLVSHPEQIREAKRIAREVGLEPHKDVAWGVMIEVPAAAIIIEDLIKEGIDFVSFGTNDLTQYTLAIDRDNERVAKLYDETHPAVLKLIKHVIKVCKRYGVETSICGQAGSDPKMARILVRLGIDSISANPDAVQLIRQVVAQEERKLMLEAARKQLFEEEEEEELF
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: UBAD1_MOUSE
Sequence: MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSTFFQETNIPYSHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHGGGGSSSPMATSATSPPPHFPHATGSFATPSWPTAASPPGGPQQHQPQPPLWTPAPPSPTSDWPPLAPQQATSEPRAHPAMEAER
What are the official names of this protein?
UBA-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UBALD family.
Protein: THI4_CANAW
Sequence: MTPPTMLQTAPVESFNLNPKSTQQAINLKSDAKNGKVSFADWNEFKFAPIRESTVSRAMTRRYFADLDKFAESDIVIIGAGSAGLSAAYTLGKNRPDLKIAIIEASVSPGGGCWLGGQLFSAMVLRKPAHLFLDDMGLDYEDEGDYVVVKHAALFMSTLMSKVLQFPNIKLFNATAVEDLITRKDPATNLQRIAGVVVNWAQLDHDTQSCMDPNTINCNVVLSTSGHDGPFGAFTAKRLEQLGRAPRDVTAGFTKPSITTSKLQEPEPISNFQLGGMKGLDMNKAEDAIVKGTREVVPGLVIAGMELAEVDGSNRMRPTFGAMALSGVKAAESVLNVLELRKQQNEACYGAYKG
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPE_STAES
Sequence: MTVLSEQDKIRLLADIVKIQTENDHEIEVCEYLKDLLSQYDIDSKIVKVNDSRANLVAEIGSGAPVLAISGHMDVVDAGDHDDWTFPPFELTDKDGKLFGRGTTDMKGGLMAMVIAMIELKQSNALKQGTIRLLATTGEETEQYGAQLLADEGYLDDVSGLIIGEPTSNIAYYAHKGSMSCVVTAKGKAAHSSMPHLGTNAVDILVDFVNEMKQEYKNIKEHDKVHELDAVPMIEKHLHRKIGEEESHIYSGFVMLNSVFNGGKQVNSVPHKATAKYNVRTVPEYDSTFVKDLFEKVIRHVGENYLTVDIPSSHDPVASDRDNPLIQNITRIAPNYVHEDIVVSALIGTTDASSFLGTNENNVDFAVFGPGESIMAHQVDEFIRKDMYLSYIDVYKDVFKAYLEK
What are the official names of this protein?
Probable succinyl-diaminopimelate desuccinylase, SDAP desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: SPEH_SULSY
Sequence: MEKTLGLHILADLYGVDFEKIDHVEDVKALLEGAVKYANLSKLSSHFHQFNPHGATGVILLEESHISIHTWPEHGYAAIDVYTCGGKEKTFKAMEYIIKTLKPKRIDEKIAERGVVPVNPEGVNIEKMQLAQV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: FRP2L_HUMAN
Sequence: MTSIPFPGDRLLQVDGVILCGLTHKQAVQCLKGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCDIMRLGRYSFSSPLTRLSTDIF
What are the official names of this protein?
Putative protein FRMPD2-like, FERM and PDZ domain-containing protein 2 pseudogene 1, FERM and PDZ domain-containing protein 2B pseudogene, PDZ domain-containing protein 5A.
Protein: MAL_HUMAN
Sequence: MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSVFCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
What is the function of this protein?
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane.  Could be involved in myelin biogenesis and/or myelin function.
What are the official names of this protein?
Myelin and lymphocyte protein, T-lymphocyte maturation-associated protein.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FPG_SALNS
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTAECDLLAQVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RDRP_I03A0
Sequence: MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEIFRSNGLTASESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNELTKKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: ATPH_JASNU
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TYPH_ALIF1
Sequence: MYLPQEIIRKKRDNKELTAEEINFFIQGVAKETVSEGQIAAFAMAVYFNEMTMPERIALTCAMRDSGMVIDWSHMNFDGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLESIAGYNITPSNDVFGKVTKEAGVAIIGQTGDLAPADKRVYATRDVTATVDNISLITASILSKKLAAGLDSLVMDVKVGSGAFMPTYEASEELAKSIVAVANGAGTKTTALLTDMNQVLASTAGNALEVREAIRFLTGEYRNPRLYEVTMALCAEMLVIANLAKDEQDARAKLQTVLDNGKAAECFGKMVFGLGGPSDIIENYDNHLESAQIIKPVFADTTGFVQAMDTRDLGMAVVGMGGGRRVASDTIDYAVGLSDMIRLGQTADNQQPLAMIHARNEEQWQQAANAVKAAIVISEKQPEATPEVYRKIRPEDV
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: POM33_YEAST
Sequence: MSSRPANNQGPPNLPARDKSLVQRFMAVAKSLQFAWFTGHSVVLISSILYLLKMSEFYYRSAYLGVIESFGIIIYQQFFTRNEPLQTQDAAATKASIKSRVAGLLKSEDVLYLVLANFWLFTPRFSFSLIPFFAFAVFHVLIYVEKVLLPKVFHLSSKDSSKILSFIDKFVVQYNDLCMHWVGTAELLIFILVLFRAILCFQRSWIILVVYAIFIKLRYENSKYMKAAFAQWRVRMDGIISHPSIPPFVKRAYNAIKMSLIRLSEYRLSGAPQVTKKQN
What is the function of this protein?
Contributes to proper distribution and/or efficient assembly of nuclear pores.  Required for normal pore density in the daughter nucleus during telophase.
What are the official names of this protein?
Pore membrane protein of 33 kDa.
What is the protein family that this protein belongs to?
Belongs to the PER33/POM33 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus, nuclear pore complex.
Protein: GLMM_SALTY
Sequence: MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: KUP_STRP1
Sequence: MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTIQSLVENQGGVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWLIIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLFGIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKHSGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVTYPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYLIKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTRIVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKRPKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQDLMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVTASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURT_STUS1
Sequence: MPRIGTPLSPSATRILLCGCGELGKELVIELQRFGVEVIAVDRYANAPAMQVAHRSHVLDMLDGAALRAVIEQERPHYIVPEIEAIATATLVELEREGYTVIPTARAAQLTMNREGIRRLAAEELGLPTSPYRFADTLDECRAAAMALGFPCLVKPVMSSSGKGQSVLRSDADIDAAWEYAQAGGRAGRGRVIVEGFIDFDYEITLLTVRHAGGTSFCEPVGHRQEKGDYQESWQPQPMAPAALAEAKRIALAVTDALGGRGIFGVELFVKGEQVWFCEISPRPHDTGLVTLVSQDLSEFALHARAILGLPIPVIRQLGPAASAVVLVEGESTQVSFGNLAEVLAEPDTALRLFGKPGVSGQRRMGVALARDTSIDAARQKALRAAAAVKIEL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: EFPL_PECCP
Sequence: MARANEIKRGMVVNYNDKLLLVKDIDVQSPSARGASTLYKMRFSDVRTGLKVEERFKGDDILDTITLTRRTVTFSYIDGDEYVFMDDEDYTPYLFKKDQIEEELLFIPEGGMPGIQVLSWDGQIIALELPQTVDLEIVDTAPGIKGASASARNKPATMSTGLTIPVPEYLSAGEKIRIHIPERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: PQQB_PSEP1
Sequence: MYIQVLGSAAGGGFPQWNCNCVNCKGYRDGTLKATARTQSSIALSDDGVHWILCNASPDIRAQLQAFAPMQPARALRDTGINAIVLLDSQIDHTTGLLSLREGCPHQVWCTDMVHQDLTTGFPLFNMLSHWNGGLQWNRIELEGSFVIDACPNLKFTPFPLRSAAPPYSPHRFDPHPGDNLGLMVEDTRTGGKLFYAPGLGQVDEKLLAMMHGADCLLVDGTLWEDDEMQRRGVGTRTGREMGHLAQNGPGGMLEVLDGFPRQRKVLIHINNTNPILDEDSPERAEVLRRGVEVAFDGMSIAL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: GERPD_BACSU
Sequence: MIFTVINRSLEVGDIRMNGVSSSSVFHIGDTESIYLSSIFDTPPESLIIGPFAPLAPE
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPD.
Protein: CIA30_GORGO
Sequence: MALVHKLLRDTYILRKFSKPTSALYPFLGIRFAEYSSSLQKPVASPGKASSQRKTEGDLQGDHQKEVALDITSSEEKPDVSFDKAIRDEAMYHFRHLKDEIVDHWRGPEGHSLHEVLLEQAKVVWQFRGKEDLDKWTVTSDKTIGGRSEVFLKMGKNNQSALLYGTLSSEAPQDGESTRSGYCAMKSRIPRGAFERKMSYDWSQFNTLYLRVRGDGRPWMVNIKEDTDFFQRTNQMYSYFMFTRGGPYWQEVKIPFSKFFFSNRGRIRDVQHELPLDKISSIGFTLADKVDGPFFLEIDFIGVFTDPAHTEEFAYENSPELNPRLFK
What is the function of this protein?
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
What are the official names of this protein?
Complex I intermediate-associated protein 30, mitochondrial, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the CIA30 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix. Note=Periferally associated with the matrix face of the mitochondrial inner membrane.