PharMolix/UniProtQA huggingface dataset:
Protein: RS18_ACIB3
Sequence: MARFYRRRKFCRFTAENVAYIDYKDIDTLKQYITENGKIVPSRITGTKARYQRQLALAIKQARYLSLIPYTDNHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CL040_HUMAN
Sequence: MNWVGGSRSRVLIKQERRKQKEYFEKHRLKSKMKSLGVLSPVKNSAVSLDILNLYMVNQISCKKKIPETVRKPTHVNMNRDIKMPLRKHNLELTMSPHCVPSKLCLDDTETNVNCQRLSSKEDLGPVQSQGMDSYSMLHPQFSKIENCSFTPSSFSVELPSNRHISKLNFTSGIAPTPQKLAYEKKQNDQRSTVNCSDSLLSKLNKSQDVFSPSHKTTRFGTLFERLNSLGNRNLLTKSPAVIMDEDCRSTDEIRQSDYITEKHSIQHIWGKNGKEVSNFLEDVNQSTPNLLSENCDSFVSQNMINVLNIDEQRIKKTFNKCDYDSMGDTCVVTSSDKNHVTDRCIRNIFTVPELTFSNSTLNKTSYPEKCQPNKKYQREYNKNERNDLSTSFENDYYPSSSERKEKFENDYQEKTPQKSIQKYPANSMGNIPSEELHSKQSWDFGLDEILMEEGGIYSLKSKRISTKKISLDSAQSSRSTSYSPRPTDSCFSSSSDLPSEDEDQISQQIEDSNRMTIKTKEKMNNFYVERMAKLSGDRIVKNDDKIHKQNENFYQFSVKNNTDQFPQLQCNSAHILQNKTNDNCVLQAARCDAGIQTESESVMEEKLDVAIQCDLISKCTCRSDVSLCNLERCSGNIKADTTGGQEIHKNN
What are the official names of this protein?
Uncharacterized protein C12orf40.
Protein: FTSB_AZOSB
Sequence: MRWPVIILAVLVVVLQYPLWLGKGGWLRVWEVDRKLHEQREENTRLEERNAGLDAEVRDLKSGNEAIEERARLELGLTKPNEIFVQVPQKH
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CCD1_PEA
Sequence: MGSEKKENGVILEVEPKPSNGFTSKAVDLLEKIIVKLFYDSSLPHHWLSGNFAPVKDETPPVKDLTVQGHLPDCLNGEFVRVGPNPKFSPVAGYHWFDGDGMIHGLRIKDGKASYVSRFVKTSRFKQEEYFNGSKFMKIGDLKGLFGLLMVNMQMLRAKLKILDVSYGHGTANTALVYHHQKLLALSEGDKPYAIKVFEDGDLQTLGMLDYDKRLGHNFTAHPKVDPFTGEMFTFGYSHTAPYVTYRVISKDGFMQDPVPITISDPVMMHDFAITENYSIFMDLPLYFRPKEMVKNKTLIFSFDSTKKARFGVLPRYAKDDKHIRWFELPNCFIFHNANAWEEEDEIVLITCRLENPNLDVVGGAVKEKLDNFSNELYEMRFNMKTGEASQKKLSASTVDFPRVNESYTGRKQRYVYGTTLDSIAKVTGIIKFDLHAEPDSGKTKLEVGGNVQGLYDLGPGRFGSEAVYVPRVPGTDSEEDDGYLIFFVHDENTGKSFVHVIDAKRMSAEPVAVVELPQRVPYGFHAFFVTEDQLQEQAKF
What is the function of this protein?
Cleaves a variety of carotenoids at the 9-10 and 9'-10' double bonds.  Probably not involved in abscisic acid biosynthesis (By similarity).
What are the official names of this protein?
Carotenoid 9,10(9',10')-cleavage dioxygenase 1, PsCCD1, PsNCED1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: LYS_MERLU
Sequence: FAGGIVSQRCLSCICKMESGCRNVGCKMDMGSLSCGYFQIKEAYWIDCGRPGSSWKSCAASSYCASLCVQNYMKRYAKWAGCPLRCEGFAREHNGGPRGCKKGSTIGYWNRLQKISGCHGVQ
What is the function of this protein?
Has bacteriolytic activity against Gram-positive bacteria M. luteus.  Also has chitinase activity.
What are the official names of this protein?
Lysozyme, 1,4-beta-N-acetylmuramidase, Invertebrate-type lysozyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHAE_THIVI
Sequence: MSNDSFFNNDWLELQRKYWDSWSEMGRKAMGLENQQTLTTPWEGALDHWWKAMSPATPDFSKTFMEKMMEQGKNFFRMAETFANTPEDTTATNGLTWWTKALEDMQKQFSGSLDDGGNSMQRMMSFWELPIDNWQRMMSSMSPMPGDMLRNMPHEQLKDRSGRALSAPGLGYTREEQSQYHQLTRTAMDYQAALQEYTGFYSQLGMKSVERMGDFIQGVIDSGKSIDSARTLYDNWISCCETVYAAEVATPEYAQIHGRLVNAQMALKRRMAIMVDENLGAMNMPTRSELRTLQDRLQETRRDNKQLHRALHALEKQVAALSGKTPTTALKAPAPATKATEKPATRATTRRKTAAKPTGGTADD
What is the function of this protein?
Polymerizes D(-)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end.  This subunit has no catalytic activity but enhances the activity of PhaC, the catalytic subunit.
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaE, PHA polymerase, ORF2, PHB synthase subunit PhaE, Poly(3-hydroxyalkanoate) synthase subunit PhaE, PHA synthase, Polyhydroxyalkanoic acid synthase, Poly(3-hydroxybutyrate) polymerase subunit PhaE, PHB polymerase, Poly-beta-hydroxybutyrate polymerase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family. Type III PhaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ECO7I
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: UHMK1_RAT
Sequence: MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGTPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLVYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGLSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPSRRIPAEMALCSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEDEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL
What is the function of this protein?
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase.  May be involved in trafficking and/or processing of RNA (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EUTC_CLOAB
Sequence: MENLLKIYDIKEEELSELKALTPARICVGRAGTRLKTNTFLKFRADHAVAMDAVWSSVDEKLIDTLNFLKVQTLAKDKEEYITRPDLGRKFSEETLDYIKNNCINEPDVQIIAGDGLSATAINANLRKIYFVIVEKLKSRGYKVGTPIFVKYARVATMDKISEELNAKVTIILIGERPGLATGESMSSYMAYESSTKKPESQRTVVSNIHNKGIPSVDAGKEIVRIIDIMMKEKKSGVELRI
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: CROL2_HUMAN
Sequence: MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDSTMQAHEDAQREVQRLRSAKELLRREKSNLAHSLQVAQQQAKELRQERKKLQAAQEELRRQRYWLGEEQEDAVQDGVRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEGRGGLPAGLPVQAERPQREPCSGQVGSEPPCHPGHSWRKKSAPCRAGSGRRSRRPQWHGKSRSGWRRCGWNRRWRGRAWRAPYERRSRPRRQWSSSSPRCIMSAAGCRSS
What are the official names of this protein?
Putative ciliary rootlet coiled-coil protein-like 2 protein, Ciliary rootlet coiled-coil protein pseudogene 3.
What is the protein family that this protein belongs to?
Belongs to the rootletin family.
Protein: GSA_LEPBL
Sequence: MSQRSSELISDSWKGSSSEELFERAKIVSPGGVHSPVRSFRSVGGTPVFFVSANGATLTDVSGKEYVDFCLSFGPLILGHRDPEVEEVVRETAGLAWSFGTAEPYSLELAEFITNRIPWAEKVRFVNSGTEAVMSALRVTRAATGREKIFKFDGCYHGHLDALLVKAGSGLAGESSSDSAGISSTAIANTLVLPLDDEMAVQKLFESEGKNIAALIIEPLPANYGLLVQRKEFLLKIVEIAKKYGTLVVFDEVISGFRTGFQGMSGLLGIRPDLVTYGKIIGGGFPVGCYAGRRDLLDLVAPSGPVYQAGTLSANPFGMRAGLATLKKAERDSIYSVLEVRTKTFADEMVKLLNGKTDQEWEAVTHSSLFWFRKKTQQAVRRIDQIPEGHKEGFAEVFHVLLKNGIYLAPSGYEVGFLSWAHNDSVIAKVLEIADKAFKEL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_BRUC2
Sequence: MNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRSPHIDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TDA11_CANGA
Sequence: MDQKFDEFIAQTESEAEIDTSSRYTTGSISPQFASPTKFKNVLPHETDTQTGQRNRVAEHQHVPKSLLNASVEESHNHPLKEDKSESRQRQVSVSNSNPSSKGMVNKRRSLIQPMMVPTTPETDRTRPQSQSNVASGNSANKNNLHPDTNHGIDINATTQTPSSMSMGNPKFSENFASLAPSSKRNSMHSRTSSSQSMAIDSSLGGSMDVNALLQSLANKELELLECKRKIDDLKKQLHMEENIYQNKANELQELKNKVSKNINVSGSNQPVFNKTSTTGRKNSRESSRRNTHVTPVKTTRNDIRQDTSLNQDMENTDDNKQSMWSKPLALFNQVDQIIQQELERTLNWDEPPTPVEETEENQEGDKSVSKSLWSFVSDLKTGLLGIEEEEDGHHTQQSNSNVNRPKNTHGQVMDNRKHANEDINLSIKEFKTTKKHLDDNSDTHLKQRSGRTAVRKTKSGNKLNFVDDSDDGDSTLEADMVEMGSFSR
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_YERPS
Sequence: MSRVCQVTGKRPMSGNNRSHAMNATKRRFLPNLHSHRFWVEGEKRFVTLRVSAKGMRVIDKKGIETVLAEIRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NDHI_OTESC
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: G6PI_PROM1
Sequence: MAITDIFQLNNNDKWERYCDLLYSDDSLGFWLDISRMDVAINDFEDFNEIYSKAFDALESLENGSIANIDEGRQVGHYWLRNPKVAPSAEISDSITKEIQNISKFGASILNGEITNRHGKKYTDVFWIGIGGSGLGPLLIKESFKRESIGLNLHFLDNVDPEGISHKLNSILPNLDSTLFVVVSKSGGTPEPLIGMEQAMKFVLDHSQNWSSRAIAITSKGSKLDVLANNENWLDIFDLPDWVGGRTSITGAVGLLPAALIGADINKFLNGASQMDALTRVKDIKNNPAALLSLAWFKSGNGKGLRDMVVLPYRDRLEVFSRYLQQLVMESLGKKFDRDENQVNQGIAVYGNKGSTDQHAYVQQLRDGIDNFFVNFIEILHDPLEIVEVKNKRPGDYLSGFLQGTRSALTEGGRQNLTITFKSFDESSLGALIALFERAVSLYAELINVNAYNQPGVEAGKEAATKIIKLQKEIEELLDDGKQRTLNEINDALSSDSTESIYLILRKLSENSDHYSMIGNQSNPDKLIISKT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAV_SULAC
Sequence: MRINILRVEYHSKTAHSILLQLDLFKKVKVICHMSQSIKFRVTEARQRDVGKKVARISETSMRKLNVEAGDYIEIIGQDGNSALAQVMPAYDISDDEIRIDGYIRKSIKVGIGDDVTVRKTNVSPASKVVLAPTQPIRFDNSFVEYVKDTLMDKPLAKGETLPIPIYTGTLELTVVNTQPSNYVYVTGSTNIEIREEPVKESSLAYPKVSWEDIGDLEEAKQKIREIVEWPMRHPELFQRLGIDPPKGILLYGPPGTGKTLLARALANEIGAYFITVNGPEIMSKFYGESEQRIREIFKEAEENAPSIIFIDEIDAIAPKREDVTGEVEKRVVAQLLTLMDGIKGRGRVIVIGATNRPDAIDPALRRPGRFDREIEIRPPDTKGRKDILQVHTRNMPITDDVDLDKLAEMTYGYTGADLAALAKEAAIYALRRFVDEKKLNLDQPTIPAEIIKELKVSMNDFLNALKSIQPSLLREVYVEVPKVNWNDIGGLDNVKQQLREAVEWPLRFPELFTKSGVTPPKGILLFGPPGTGKTMLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPTVIFFDEIDSIAPIRGLSTDSGVTERIVNQLLAEMDGIVPLNKVVIIAATNRPDILDPALLRPGRFDRLIYVPPPDKTARFEILKVHTKNVPLAEDVSLEDIAEKAEGYTGADLEALVREATINAMRSIYSMCDKQSRDECKGNMECYQKHIKECMNKTSFKVSKEDFEKALNVVKASLTQADIQRYERFSKELKRAIA
What is the function of this protein?
Not yet known, shows ATPase activity.
What are the official names of this protein?
Protein SAV.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. CDC48 subfamily.
Protein: KAD_CAMJR
Sequence: MKELFLIIGAPGSGKTTDASLIAQADATNITHYSTGDLLRAEVASGSELGKTIDSFISKGNLVPLDVVINTIVCALKAAPTKTIIIDGYPRSVEQMMEFDKVLSEQNEICLKGVIEVRVSEEVAKERVLGRNRGTDDNEEVFYNRMKVYTEPLNEILDFYQKKKLHFIIDGERAIEPIVADMKELIKKIQSI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ACTP2
Sequence: MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGGILSEAMARAGATVTGIDMTTEPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFDVITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTLKAYMLVIIGAEYVLKMLPKGTHEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: ACKA_STRPJ
Sequence: MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIA7D_HUMAN
Sequence: MKAPGRLVLIILCSVVFSAVYILLCCWAGLPLCLATCLDHHFPTGSRPTVPGPLHFSGYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTE
What is the function of this protein?
Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of glycoproteins and glycolipids forming an alpha-2,6-linkage.  Produces branched type disialyl structures by transfer of a sialyl group onto a GalNAc residue inside the backbone core chains.  Prefers O-glycans to glycoproteins or glycolipids.
What are the official names of this protein?
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase, NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV, ST6GalNAcIV, Sialyltransferase 3C, SIAT3-C, Sialyltransferase 7D, SIAT7-D.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: VP4_ROTPG
Sequence: MASLIYRQLLTNSYTVELSDEIKTIGSEKSQNVTINPGPFAQTTYAPVTWRHGEVNDSTTVEPVLDGPYQPTSFKPPNDYWILLNPINKGVVFKGTNRTDVWVAILLIEQRVPSQDRQYTLFGEVKQITVENSSDKWKFFEMFRNNANIDFQLQRPLTSDTKLAGFLTHGGRVWTFNGETPHATTDYSTTSNLPDVEVVIHTEFYIIPRSQESKCNEYINTGLPPMQNTRNVVPVALSSRSITYQRAQVNEDIIISKTSLWKEMQYNRDITIRFKFGNSIVKLGGLGYKWSEVSFKAANYQYNYLRDGEQVTAHTTCSVNGVNNFSYNGGSLPTDFSVSRYELIKENSYVYIDYWDDSQAFKNMVYVRSLAANLNSVKCSGGNYNFKIPVGAWPVMSGGAVSLHFAGVTLSTQFTNFVSLNSLRFRFSLTVEEPSFSILRTRVSGLYGLPAANPNNGNEYYEIAGRFSLILLVPSNDDYQTPIMNSVTVRQDLERQLGDLREEFNSLSQEIAMTQLIDLALLPLDMFSMFSGIKSTIDVAKSMATNVMKKFKKSGLATSISELTGSLPSAASSVSRSSSIRSNISSISVWTDVSEQIADASNSVRSISTQTSAISKRLRLREITTQTEGMNFDDISAAVLKTPLDKSTHISPDTLPDIITESSEKFIPKRAYRVLKNDEVMEADVDGKFFAYRVDTFEEVPFDVDKFVNLATASPVISAIIDFKTLKNLNDNYGITRSQALDLIRSDPRVLRDFINQNNPIIKNRIEQLILQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: RS3_PROA2
Sequence: MGQKVNPTGFRLGIIRDWTSRWYDDSPVIAEKLKQDHVIRNYVQARLKRERAGIAKIVIERTTKHIKINIFAARPGAVVGRKGEEINNLSQELSRITGREVKIDVIEVIKPEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRAGAEGIRIRCAGRLGGVEIARSEQYKEGKIPLHTLRANVDYASVTAHTIAGAIGIKVWVYKGEVLVQRIDAIEEDELKKIKDRRGEQRSRGRDSRNRRRRKPRQTT
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: BGL21_ORYSJ
Sequence: MERPLHLLLVFLSSPWLLLLQGVSSLQFTRDDFPHDFAFGAGTSAYQYEGGAAEDGRTPSIWDTYTHSGRHPEDETGDVASDGYHKYKEDVKLMSEIGLEAYRFTISWSRLIPSGRGAVNLKALQFYNSMINELVKAGIQIHVVMYHMDLPQSLQDEYGGWISPKIVDDFTAYADVCFREFGDRVVHWTTVLEPNAMAQAGYDMGILPPNRCSYPFGSNCTAGNSSVEPYLFIHHSLLAHASAVRLYREKYKVAQKGIIGINIYSMWFYPFTDSAEEIGATERAKKFIYGWILHPLVFGDYPDTMKKAAGSRLPIFSNHESEMVTNSFDFIGLNHYSSVYTSNNNNVVKAPLQDLTADVATLFRVTKNDTPTPVFVPGTIVDPRGLEHALKYIREKYGNLPIYIQENGSGSSSETLDDVERINYLAKYIAATLKAIRSGANVKGYSMWSFVDLYELFGGYSTWHFGLVAVDFDSEKRRRQPRRSASWYSEFLKNNSVIRVEEDGFVSAASHAQL
What are the official names of this protein?
Beta-glucosidase 21, Os5bglu21.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: CAS10_STRTR
Sequence: MKKEKIDLFYGALLHDIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLGNDHLAYITYIADNIASGVDRRQSNEESDEDASAKIWDTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQAQIDSLLNLFEAILSFVPSSTNSKEIADISLAEHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKASAFYEEEAFLLASFDLSGIQDFIYNIATSGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANLLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQIYQKASRMISEKKISRYDYRTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQESFSRVYVKNDYKAGTIKATHVFVGDYQCDEIHKYAALSKNEDGLGIKRLAVVRLDVDDLGAAFMAGFSRQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRQNFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNYESEEKMNVARLAYYLTRLEELTDKDERDKFKQFKKLFFKWYTNNESDRKEAELALLLYVYEIRKD
What is the function of this protein?
When associated with the ternary Csm effector complex (the crRNA, Cas proteins and a cognate target ssRNA) synthesizes cyclic oligoadenylates (cOA) from ATP, producing cyclic triadenylate (cA3) up to cyclic hexaadenylate (cA6), which is the active cOA.  The enzyme is also able to cyclize pppA3 up to pppA6.  cOAs are second messengers that induce an antiviral state important for defense against invading nucleic acids.  Synthesis of cOA can occur with AMP plus ATP, 2'dATP or 3'dATP (but no other nucleotides), and requires a free 3'-OH ribose moiety.
What are the official names of this protein?
CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ssDNase Cas10, Cyclic oligoadenylate synthase, StCas10.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Cas10/Csm1 family.
Protein: HEM3_COLP3
Sequence: MNNTTVRIATRKSALALWQAEYVKAQLEHFHDGINVELVPMTTKGDIILDTPLAKVGGKGLFVKELEVAMLEDRADIAVHSMKDVPVDFPEGLGLEVICPREDPRDAFVSNTIKSLSDLPQGSIVGTSSLRRQCQLKASRPDLDIRDLRGNVNTRLRKLDEGQYDAIILAAAGLIRLEMSERIAQFIEPEEMLPANGQGAVGIECRNDDATIKALLAPLECATTRIRVLAERAMNRALQGGCQVPIGSYGVISADGKNIHLRGLVGSVDGSEMIESEITGPVEEGEALGNKLAQELLSRGADKILQQVYSENDIKNS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GCS2_ECO55
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNEITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCENERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKMGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.