PharMolix/UniProtQA huggingface dataset:
Protein: ARNC_ENT38
Sequence: MTKVEAIHKVSVVIPVYNEQESLPELIRRTTAACELLGKDYEILLVDDGSSDESASMLSDAAEEPGSHIVAVLLNRNYGQHNAIMAGFSHVTGDLIVTLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDTWFRKRASRLINRLIQSTTGKAMGDYGCMLRAYRRHIIDAMLHCHERSTFIPILANTFARKAIEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSVFGSIIAVLGFTLSVLLVVLRIAFGPQWAADGVFMLFAVLFMFIGAQFVAMGLLGEYIGRIYTDVRARPRYFIQRVVSRGSVSTSKENQQ
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FA13C_HUMAN
Sequence: MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI
What are the official names of this protein?
Protein FAM13C.
What is the protein family that this protein belongs to?
Belongs to the FAM13 family.
Protein: RL17_ECOL6
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SC6A2_HUMAN
Sequence: MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQRDIRQFQLQHWLAI
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (PubMed:2008212, PubMed:8125921).  Can also mediate sodium- and chloride-dependent transport of dopamine (PubMed:8125921, PubMed:11093780).
What are the official names of this protein?
Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET, Solute carrier family 6 member 2.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSG_METVS
Sequence: MAMSMKKIGAIAVGGAMVASALATGALAAEKVGDVDAFAANAVTNGNVNVDIVVGSNAAAKDVVSAANIAAKVGSLMFKEGSATDGNAKVTVSASSKSDNIKNIWDAGNAFAATNEVFLFAAADDDYTGTAAGTGVPNYLLGKTFMDYTVPPAAQVIDLEDLQTLAAVSDADPSGWDIFGTNKDFEAAEAVAAVIRTQQPAAALFNTGADLQVSEDEAFYMSLAFEEDKYGSALADYARLFPGMRIPFLGQEMVVVKLDTDDDLVILGKEVYDGVVKQRGDNYDLGNGYAVKVNNVLTQGAAYKADVQLLKDGKVVASKFDTIDGNGNQITIVYKDIGIVVNDAWEDIGGNYGFAEMVITKDVVTLELGEEYINDWEAYAVRATAAGLIESDSATSTAAVPVVGIALKYVGDDVDKIRKDKTFSIANYAKLDFDEDSGDMAVQFLMDDAKDVTLSIGQKVSVLNAEIKLNELMADAKQSVPMTAPIAKLDAEASLSAANKDLILVGGPVVNTLAKELADKGLIAIDNASPATLAVAKGAANGKDVLVVAGGDRDKTAAAATALIAML
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
S-layer protein, Cell surface glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the Mj S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: NACC2_MOUSE
Sequence: MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAAYVTSPSVPIPLLTRVKHEAMEMPPASGPGLASKRPLETGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPPGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAAPQVFEQRIYAERRSDAATIVALRTDAVNVDLSTSANPAFEANEEVDGGGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL
What is the function of this protein?
Functions as a transcriptional repressor through its association with the NuRD complex.  Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 (By similarity).
What are the official names of this protein?
Nucleus accumbens-associated protein 2, NAC-2, BTB/POZ domain-containing protein 14A.
What are the subcellular locations of this protein?
Nucleus. Note=Predominantly associated with chromatin.
Protein: HIS4_NOVAD
Sequence: MIVFPAIDLKAGQVVRLAEGDMDRATVYGDNPAHQASLFAQAGSQYLHVVDLDGSFAGRAENREAVEGILKSFPGHVQLGGGIRTREAVSGWFDLGVSRVVMGTAALKDPQFVKDMAKEFPGGIVVAVDARDGMVATEGWADVSDVSVVDLARRFEDAGVASLLFTDIGRDGLLKGVNLDATVELARRVDIPVIASGGVKGIDDIRMLKIHEGDGIEGVITGRALYDGRLDLKAAIEMAEA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKN3_SCHPO
Sequence: MFRNYNWFDAKEPISYESEIYAKGLKFQRPQITVDGRHWEQLAVERMTKDAAGYVYGCAGKRETYDKNMESFKKWSIIPNRLIKSGFPDLSTTVFGQKYPFPIALAPVGVQKIFNPEGESGSCAAATREHIPYIISTASATSFEDIEKASGPGERWYQLYWPSNDHQDITISLLNRAKKTGCRVLIVTLDTFILGWRPSDMDNGYDPFLNPDSIGVEHGFSDPVFRKQFKEKHGVEVEENMLEAAKEFAGIVFPGISHDWEDLKFLRKHWDGPIVLKGIMNVPDAKKAVEYGMQGIVVSNHGGRQQDGGVASLTMLPKIVDAVGDKLDVLFDSGVRSGADIAKALALGAKMVLIGRPYVYGLALEGSSGVSHVIRCLLGDLELTLHLSGIVSVKPKDLNRDVLYKEE
What are the official names of this protein?
FMN-dependent alpha-hydroxy acid dehydrogenase PB1A11.03.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYQ_YERPE
Sequence: MSEAEARPSNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDYQGQCNLRFDDTNPVKEDVEFVESIKRDVEWLGFTWSGDVRYSSDYFDQLYQYAVELINKGLAYVDELTPEQMREYRGTLTAPGKNSPYRDRSVEENLALFEKMRAGGFAEGTACLRAKIDMASPFIVMRDPVLYRIKFAEHHQSGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIDCHPRQYEFSRLNLEYTIMSKRKLNQLVTEKVVEGWDDPRMPTISGLRRRGYTAASIREFCRRIGVTKQDNNVEMMSLESCIRDDLNEHAPRAMAVLDPIKVVIENRAAGEEWLTMPNHPNNPEMGSRQVPFDSEIYIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNVTTLYCSYDAETLNKDPADGRKVKGVIHWVSVAHALPAEIRLYDRLFNVPNPAAAEDFLSTINPESLVIRQGFVEPSLADAVSDKTYQFEREGYFCADSRYSRPGALVFNRTVGLRDTWAAKATQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA1B_ASPCL
Sequence: MYHRNSAPPPPGWSGGYPPPQSQWPPHSYQYPPYPPQGPPPPPAHSYSPPPTYGNYPSPYSTPPPHSPSPYQHPQHGHSRSWTNPSLPPRPPRESQSFGKGAPSNYRFQYSECTGRRRALLIGINYIGQPNQLRGCINDVTNMSTFLHERFGYRREDMVILTDDQKNPMSVPTKINILRAMQWLVKDAQPNDSLFIHFSGHGGRTPDLDGDEEDGYDDVIYPVDYRVAGHIVDDEMHNIMVRPLQPGVRLTAIFDSCHSGTALDLPYVYSTQGILKEPNLAKEAAQDLFSALASYGKGDLSGVAMTAIGFLKKAAIGDSARQRTVMTKTSPADVVMFSGSKDTQTSADTFQDGEARGALSWAFIKSQKQRPNQSYLQLLNSIRAELEGKYTQKPQLSCSHPLDVNLLFVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: NUOI_FRAP2
Sequence: MRNITSFFKTFLLWELLKGMKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGSRRTSSYEIDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYDND_BACAN
Sequence: MAERTHACGKVTVEAVGQTVQLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPETSKEALEVAETIRSEYVLHVEGTVVERGEGAINDNMATGRIEVQATKVSVLNAAKTTPIIIADDTDASEDVRLKYRYLDLRRPVMFNTFKMRHDVTKTIRNFLDTEEFLEVETPILTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMVGGFERYYQVARCFRDEDLRADRQPEFTQIDIEASFLTQDEILDMMERMMTKVMKDAKGVEVSAPFPRMKYADAMARYGSDKPDTRFEMELTDLSEFAAGCGFKVFTSAVESGGQVKAINAKGAASKYSRKDIDALTEFVKVYGAKGLAWLKVEEDGLKGPIAKFFGEEDASVLMNTLEATAGDLLLFVADKKSVVADSLGALRLRLGKELELIDESKFNFLWVTDWPLLEYDEDADRYFAAHHPFTMPFREDVELLETAPEKARAQAYDLVLNGYELGGGSLRIYERDVQEKMFKALGFSQEEAQEQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCLLTEAPSPVAEAQLEELNLKLNVKEEK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAMP1_CAVPO
Sequence: MVRVLRGLPWRGLWLLLAHQLFLVTACQDAHYGTLMQELCLSRFQKDMEAMERTLWCDWGKTIGSYGELTDCTRNLAERLGCFWPNVEVDRFFVAVHRHYFRSCPASGRALGDPPSTILCPFVVLPITVTLLVTALVVWRSKRAESIV
What is the function of this protein?
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane.  Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL (By similarity).
What are the official names of this protein?
Receptor activity-modifying protein 1.
What is the protein family that this protein belongs to?
Belongs to the RAMP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CEP76_HUMAN
Sequence: MSLPPEKASELKQLIHQQLSKMDVHGRIREILAETIREELAPDQQHLSTEDLIKALRRRGIIDDVMKELNFVTDSVEQELPSSPKQPICFDRQSTLKKTNIDPTRRYLYLQVLGGKAFLEHLQEPEPLPGQVCSTFTLCLHYRNQRFRSKPVPCACEPDFHDGFLLEVHRESLGDGTRMADSTTMLSISDPIHMVLIKTDIFGETTLVASYFLEWRSVLGSENGVTSLTVELMGVGTESKVSVGILNIKLEMYPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPSHNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQAARFVNVLGYERAPVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVFDLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHRKDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHFVYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRSVL
What is the function of this protein?
Centrosomal protein involved in regulation of centriole duplication.  Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
What are the official names of this protein?
Centrosomal protein of 76 kDa, Cep76.
What is the protein family that this protein belongs to?
Belongs to the CEP76 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Does not localize along the ciliary axoneme.
Protein: PANZ_SALTY
Sequence: MKLTILRLEHFSAQDQIDLGKIWPEYSASSLSVDETHRIYAARFNERLLGAVRVTLSGTQGALDSLRVREITRRRGVGQYLVEEVIRDNPNVSSWWMADVGVEDRSVMAAFMQALGFTAQHDGWEKR
What is the function of this protein?
Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion (By similarity).  Binding of CoA or a derivative to PanM leads to interaction with PanD, which promotes the processing and activation of pro-PanD, and subsequent substrate-mediated inhibition of the active form of PanD (By similarity) (PubMed:22497218, PubMed:22782525).  Lacks acetyltransferase activity (PubMed:22782525).
What are the official names of this protein?
PanD regulatory factor.
What is the protein family that this protein belongs to?
Belongs to the PanZ/PanM family.
Protein: VPB51_MYCTU
Sequence: MAKHLVDIDEQALNMARTELGTTTIKDTVNAALRQATSQRVQRVAAALDTLAAAPPEDRAEAWR
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC51.
What are the official names of this protein?
Putative antitoxin VapB51.
Protein: Y093_MYCPN
Sequence: MGSNAVPSLWYWVVGEDQESGRATWWAHTELNWGTDKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAYLIAGLDVVADHLVFAAFKAGAVGYDMSTENSAATKDQALAWSTTAGLDSAGGYKALVENTAGLNGPINGLFTLLDSFAYVTPVSGMKGGSQNNEEVQTKYPVKDDSKASAKIASLINASPLNSYGDDGVTVFDALGLNFNFKLNEARLPSRTDQLLVYGIVNESELKSARENAQSTSDANSNTKVKWTNTASHYLPVPYYYSANFPEVGNRRRAEQRNGVITIKRPSTQR
What are the official names of this protein?
Putative MgpC-like protein MPN_093.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: CCKAR_CANLF
Sequence: MEVADSLLGNGSDVPPPCELGLENETLVCLEQPRAAKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIATTWCLSFTIMTPYPIYSNLVPFTKTNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSARDRNPSTGSSGRYEDGDGCYLQKARPRRRLELRQLSTPGSGRLNRIRSTSSTANLMAKKRVIRMLMVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFLATFPCCPHPGPPGPRGEVGEEEEGRTTGASLSRYSYSHMSASAPGP
What is the function of this protein?
Receptor for cholecystokinin.  Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach.  Has a 1000-fold higher affinity for CCK rather than for gastrin.  It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_LEPBJ
Sequence: MSEKMYATLKTAEKIFSEISSVITKQEGLEILNGSIPLTTCLDKAFQERNRYFYNKVRIHILDNIKNGYCPEDCGYCAQRKNANSGIKEYPMKSEAEIYEDAVQAKKNGAYRFCMVTSGTGPNRLTTERLASTIRRITNELGMKVCLSAGLLDEEKAQVLKSAGLDRYNHNLNTSENHYPEICDTHTYAQRTQTLDSVSKAGIGMCSGVIVGMGESFQDIVDMAFELKSFRVISIPVNFFIPVKGHAIKNPGILTPELCVRILCLFRLVNPDSEIRIAAGREGHLRSLSAMALFAANSLFSSGYLNVKGSEIIETVTMIRDAGFVPELVDGGILPEESGTEMLYSEKNFPELYKFKKS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RLME_BURVG
Sequence: MAKNRFNQHWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYARNKLAQGKQRDAQREGGIDGTIIALDLLPMEPIADVHFLQGDFREDDVLHQLEGVLEGRPVDLVISDMAPNLSGVASADAARIEHICDLALEFAQNHLKPEGALLVKCFHGSGYSQIVEKFKQQFKVVAPRKPKASRDKSSETFILGRQLKHPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_STAAB
Sequence: MIPGEIITKSTEVEINNHHPETVIEVENTGDRPIQVGSHFHFYEANAALDFEREMAYGKHLDIPAGAAVRFEPGDKKEVQLVEYAGKRKIFGFRGMVNGPIDESRVYRPTDENDEYAGVYGDNGDENVNKKGGKRS
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_PSEFS
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQDDVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYGGQGLYEPLDLRIALCKLMTAGRVGDVEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLIGLADKIIDVVDTGNTLRANGLEPQDFIADISSRLIVNKASMKMQHARIQALIDTLRKAVESRHRG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ECOL5
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDHDKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: HIS5_BACMK
Sequence: MIAIIDYGMGNIRSVEQALKYIGTEYIITDDKKEILRSDGVILPGVGTFPKAMGVLEEKDLVCVLKEVGSLGKPLLGICLGMQLLFEKSEELQNCNGLNLLPGVIRKLKVPYKIPHMGWNELKKEGEISLWNGVEDGSFVYYVHSYYADCPNEIVYGASEYGVKVPGFVAKGNIFGAQFHPEKSGEIGMRMLKNFKGVVEAWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SHEPC
Sequence: MAELKNDRYLRALLKQPVDMTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNHELACEVTLQPLRRYELDAAILFSDILTVPDAMGLGLYFEAGEGPRFERPTDTIDAIKKLSIPDPEDELGYVMKAVSTIRRELNGAVPLIGFSGSPWTLATYMVEGGSSKTFEKIKKMAYAEPAALHMLLDKLADSVILYLNAQVANGAQSLMIFDSWGGALSHTAYREFSLRYMQKIVDGLTRFADGRQVPVTLFTKGGGLWLEAMAETGCDALGLDWTVDIADARRRVGHKVALQGNMDPSMLYAPIPRIEEEVSQILAGYGEGTGHVFNLGHGIHQHVDPEHAGAFIKAVHAQSKQYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_ANAPZ
Sequence: MAKIVSGDDVIVITGSDKGKVGKVVKILRKGGRVLAKVASVALCRKSVKPSKNREGGIFSIERFIDISNVAFFDSEAGVRTRVGYKFVDGKKVRYLKSSGRVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CYSC_ECOL6
Sequence: MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: COAD_ECO55
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_POLSJ
Sequence: MSQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIAGAVSSSVASTERLQAIGIKVFDATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVAAQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQFAALGGTATLRSKGGAESGEPLVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.