PharMolix/UniProtQA huggingface dataset:
Protein: FAR10_TYRGL
Sequence: PASDSGFLRDP
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-10, FMRFa-10.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_PROM2
Sequence: MRQHVNPLSSNFNKIERIPSLSEMFGDSKLNLHLDIGCAAGEFLFNLASVNTSWNYLGIEIREKLVKNAKLKVFEREIKNLYFVFGNANNILNDVQSKYIIRNIKSISFNFPDPWFKKRHYKRRVIQPEFINVLSNQLQKGTLIFIKTDVKELFDYMDRTISSNFYFKKIDKKDFNYSESFNPNKVKTNRENYVIVNQINIFERIYMRI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MDR4_TRIIM
Sequence: MAVEEKNSPTGAAMTNTGILVPSSQQSLPEWWTKTQKFFSRENTITPTFGYFRLLFGTQPGKTDIALIVIGTIAGIGAGIPFPLLGILFGELVDDLNSSTCSTTQAPPGGYQAAITTKVLQVIYVSILNFVCMYIHTGCWSMVGERLVRRLRTKYFHSLLRQEIAFTDTLPSGDVTSRLVSDIEVIQAGTSEKVGLFIGTISYFVAAYIVAFLKVATIAAMLMSVVPIYFLMAFGGGHYIKKYSGRISTHINAATSIVSSSLSHMSIVHAFNANARLEALFAQHLVSARMDALKKAITHSIQFGMLYFVAYASNALAFWQGSRMIADLAEGKPSKVSVGAVYTVIFVLLDASFVLSQMAPFMHIFASAASAGDRLMTTIKRQSAIDGTSSEGDSTISLASEEIELQDVTFNYPARPEVPVLQGVSFKIPPNKHTAIVGTSGSGKSTVVALLERLYDPITGCVRVGNRDLKEINVRHLRGSIGLVQQEPNLLDRSILENIAHGLVSSSQEKHKHLLPTLLGPSLSELTEKIRQGASEDEAVTEQGDVVREIVNLTRHAATLSNAIDFINALPDGLATRVGSSGAELSGGQKQRIALARALIRDPPVLLLDEATAALDSTSERLIQAALNKVSENVTTVSIAHRLATAKDADNIIVMQKGRVMEQGTHMDLVARDGVYAGMVRLQNIGKFSSSSSIMTESTQVDANIDRSLTTDTLLNKEEKLSLEQGVLDEKEKPAQLYMPEEADSLPTEPENEKEKPKQTLWATMKGSFPLIRPNILLISLGLITSIMIGVSYTGEAVIFGHTVGSLSVCRGGPSIRSSGMLFGLLFFILAIVKFAAVIVNGAAFGWAAEKTLYRTRVLSLRSLLRQPLEWHNADGRTPGLLVALVTSDASALSSLTGTTIGVLFSTVANLFAGVILSHVIAWKIAVVLLATLPVLLASGVLRLRVMAQYQKKHQKAYAKATAITVESVDNIKSIAAFSLEQEAYSVFNRSLKAPYKSNMKSVLHGNFWLSLAYSISTLVYALAYWWGSQQILAGMYTQVQFFIVLPALLFSTQSCGQMFALVPDISKARIAASNIVDLLSIKHEGDEEYDKTGSKASAKHTDPRFNMLEDKPRDVEAQLITTTPSSFPTKGMGVQFRNVHFRYPSRPNQPALDDLSINISPGQFCALVGPSGSGKSTTFALLEKFYNPASGSIIIDGVDITKQSGAAFRDTIALVPQENVMFEGTVAFNIGLGARPDVEATQEEIEEACRLANIHDTIAALPDGYNTVCSQDGKQFSGGQRQRLSIARALVRKPRLLLLDESTSALDVESEKHVQDALAKVARKTTIVAIAHRLNTIHRADRIFMIEGGRCVDQGTHAELVERCESYRANVIHQSLDA
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds.
What are the official names of this protein?
ABC multidrug transporter MDR2, Multidrug resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_PECCP
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSVSQTEEVATAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: 2A5E_MOUSE
Sequence: MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPTSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  Interacts with cyclin G in vitro.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, PP2A B subunit isoform B'-epsilon, PP2A B subunit isoform B56-epsilon, PP2A B subunit isoform PR61-epsilon, PP2A B subunit isoform R5-epsilon.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHB4_ARATH
Sequence: MGSQQVAISFLTNLAKAAFGLGVAATALNSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPYLQTPHIYDIRTKPHTFSSKSGTKDLQMVNLTLRVLFRPEVSRLPYIFQTLGLEYDEKVLPSIGNEVLKAVVANFNADQLLTERPQVSALVRDALIKRAREFNIELDDIAITHLSYGAEFSRAVEAKQVAQQEAERSKFVVMKADQERRAAVIRAEGESEAAQLISDATAKAGMGLIELRRIEASREVAATLARSPNVAYLPGGQSMLFNLNPGR
What is the function of this protein?
Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
What are the official names of this protein?
Prohibitin-4, mitochondrial, Atphb4.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass type II membrane protein.
Protein: RS21_ACIBT
Sequence: MPQVKLKEGEPVDVAIRRFKRSCEKAGVLADVRKREFYEKPTQERKRKKAAAVKRYQKKLARESVRTTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PDXS_FRATW
Sequence: MSDINIKIGLAEMLKGGVIMDVVNAEQAEIAQQAGAVAVMALERVPADIRKDGGIARMSDPKLIKEIMSVVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLTPADELNHIDKDSFKVPFVCGCTNLGEALRRIGEGAALIRTKGEAGTGNIVEAVRQLRQVNKDINYIKNADKSELMAIAKNLQAPYDLVTYVHKNGKLPVPNFSAGGVATPADAALMMQLGAESVFVGSGIFKSADPLKRARAIVSAVTYYNDAKILAEVSEDLGEPMTGINCDFEKFSQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y1463_THESM
Sequence: MLINKTKGKVWTGRVKIADTFFKRFRGLMLTPNVNYALVFILPSETRLNASIHMFFMLQSIDVIFLDSSREVVDLKRARPWRFYVPKGGAKYIIETPVGVIDYLNAEIGDEIDWEVEEERSAIPSPVEALNKIGIKNSNGTISLAEPKPKLKGE
What are the official names of this protein?
UPF0127 protein TSIB_1463.
What is the protein family that this protein belongs to?
Belongs to the UPF0127 family.
Protein: SMTL1_BOTBR
Sequence: MASELFATYYPRVVEAAQQLAPWQIAAGVTAAVVIGGYIWIITELRSPRRTGTSLFKLSGGGIKKHDVAKFMDGYEKSYKTQEDGALTWHHISKEDSVKMVNTFYDLVTDAYEWAWDISFHFSCRPVWANFAQAQVLHECRIANLARIQPGMKVIDVGTGVGNPGRTIASLTGAHVTGVTINAYQIKRALHHTKKAGLLDMYKPVQADFTDMPFADESFDAAFAIEATCHAPKLEQVYAEVYRVLKPGAYFAVYEAVSKPNFDPKNKRHVEIINSLVYGNGIPDMRTWKEAEEAGKKVGFKLHFSYDAGEASSVLAPWWERPRNLVNTGVIAYTKFAIKVCDKIGILPRDYAKFAKCVGDCIPDAVESGELGIFTPMYVYVWQKPEKST
What is the function of this protein?
Unable to convert squalene, botryococcene, cycloartenol, zymosterol or lanosterol to mono-, di-, tri- or tetramethylated derivatives.
What are the official names of this protein?
Sterol methyltransferase-like 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: NHLC2_CHICK
Sequence: MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLVYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGRLTQVELTHSFITN
What is the function of this protein?
Required for normal embryonic development.
What are the official names of this protein?
NHL repeat-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RSMH_CROS8
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEQGRLLAIDRDPQAIAAAAAIDDPRFSIIHGPFSALGDYVRERELQGKIDGILLDLGVSSPQLDDPERGFSFMRDGPLDMRMDPTRGQSAAEWLRNAEEADIAWVLKTFGEERFAKRIARAIVERNRELPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKGAVEVLAPGGRLSVISFHSLEDRLVKRFMREQSRGPQVPAGLPMTEAQLQKLGGRELRALGKLMPGEAEVAENPRARSSVLRVAERTGA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_ECODH
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PFKA_MACCJ
Sequence: MKKIAVLTSGGDAPGMNAAVRAVVRKAMYYDIEVYGVYQGYQGLINNNIKKMERGTVGDKIQRGGTFLQSARCPEFKDPEVRKQAIANLNNLGIEGLVVIGGDGSYRGAQRLNEEGIKTIGIPGTIDNDINGTDFTIGFDTALNTIVEAIDKIRDTASSHERTFIVEVMGRDAGDLALWSGLAGGAETVLCPEHRKDVKVIADKIQQGIERGKKHSIIVVAEGVMTGEECGQELKKYINVDTRISVLGHMQRGGSPSGMDRVLASRLGGYAVELLMNDETGLAVGIQNNSLSKTKFEDIFTSVHHLDEKMYELSNELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5632_DICDI
Sequence: MCIFFFFKKLFFVEINVCLSFFFLFYFIFVLFFAAEVRNNDF
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0286783.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDC_CLOAB
Sequence: MFKINALNNLFVQFFDSINKFVYNIVPDKNYSYGLAIIILTIIIKTLLVPFSIKQIKSSVLMNALQPELKKLQTKLKSDPQKLQQETMKLYKEKNVNPFGGCLLLIIQYPILIALYYVFYSLHIKGIGFLWIHDLSQKATFSNWTTWILPIVSGATTYLSGILTMPPSSDPAQRKQTTTMNIGMSIFLLWMSWNFSAALVLYWTVSNLFQMAQSKIIITAVTAKLEAEKNSVEDSSNIISQNIDNKKNKKNKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COXX_SULIA
Sequence: MSLQQKIKAYLKLGKLGVVSLLDLAAVAGAFLAYKHGISLLPIIPMFIGGTLASMGAMIINSGIEIDRDKVMSRTSKRPTVVGYVNRKEAIIVGSLLAILGTALGFIDNILTAFFIALGVVIYIFVYTILLKPRTWLNIVIGGFAGSAAAWAGYTSLTNSLTLEGFLLGFLIFMWTPGHFWSLALKYREDYVNAHYPMLPAVVGITTSARAIAISNALMIPIVLLLGYYINLIALIAFSILSLFLMFLSYRLILNPTKEEAIKSFIFSNIYLMLILLIMIIVKLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_CHLPM
Sequence: MQQFFRPVIQDALRSAGIETGQPVQIEKPASAKFGHFSTNIAFLSAKELGKNPRTLAQELIGHLRFPSGSIEKTEVAGPGFINFFLTPPFIMDSLGEVLRQGEAFGRGTSGNGEKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLFEAEGYSVTREYYFNDAGRQMQILGESVRFRYLERCGRKVDFPDTHYQGGYIGDIADRIYQEQGDSLADAEGTGEFKSTAEAIIFSSIKKTLERLGIRHDSFFNEHTLYTPDENGATRNSRVIDALRQKGFIDEYEGATWFLTTKLGQEKNKVLVKSTGEPSYRLPDIAYHLTKYDRGFGVIVNVFGADHIDEYPDVIEALKILGHDTSRIRIAINQFVTTTVDGETVKMSTRKGNADLLDDLIDDVGADATRLFFIMRSKDSHLNFDVDLARKQSKDNPVFYLQYAHARICSLLRMAWSENGFNPEKLPDLALLKTLSSPEELQLALALLDFPDMVRSALRLLEPQKMVDYMHSIAELYHRFYQECPILKAEADTANARLLLSLATRQVLQNGFRILGISAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_METSB
Sequence: MRYLPLNSEDRSEMLARIGVDSIDALFSSIPEASRLSRDLDLPLRRSEMETQRLLSGMAARNTPASSAPFFIGAGAYKHHIPASVDHLIQRSEFLTSYTPYQPEISQGTLQAIFEFQTQVAALTAMDVANASMYDGSTATMEAVLMAHRVTKRRKAVLSGGLHPHYADVVRTVSKMTDNDALSLPPDVFAAEDLAAEIDEETSCVVVQTPDAFGNLRDLSPLAAACKEHGALLIAVFTEAVSLGLVKPPGAMGADIVVGEGQSIGNGLNFGGPYVGLFATRQKYLRQMPGRLCGETVDADGRRGFVLTLSTREQHIKRDKATSSICTNAGLCCLAFTMHLTLLGEAGLRQLARVNHANAVDLAGRFAQIYGVEVLNRSFFNEFTLRVPGPAAEIVEHLAQKGILGGVPASRLWPGEDLDDLMIVASSEINTDEDRAAFASALRGIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: SRPRA_HUMAN
Sequence: MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA
What is the function of this protein?
Component of the signal recognition particle (SRP) complex receptor (SR) (PubMed:16439358).  Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (PubMed:16675701, PubMed:34020957).  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54 (PubMed:34020957).  SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER (PubMed:34020957).
What are the official names of this protein?
Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain.
Protein: PROB_STRGC
Sequence: MKAKRIVFKVGTSSLTNADGSLSRAKVKEITRQLALLHEAGHELILVSSGAIAAGFSSLGFKKRPTKVVDKQASAAVGQGLLLEEYTTNLLLKQIISAQILLTQDDFADKRRYKNAHQALSVLLNRGAIPVINENDSVAIEELKVGDNDTLSAQVAAMVQADLLVLLTDVDGLYTANPSTNPDARRLEKIEKISSELIDIAGGAGTSNGTGGMLTKIKAATLATMSGVPVYICSSLKTDALLEAAEETKDGSLFLAQEKGLKTQKQWLAFYAKSQGEIYVDQGAADALRNKGKSLLVSGLVSVSGSFAYQDTVTVYEEGSGAILGKGRVRFGELALKDMLKSNKPKGVVIHRDDWISLTPELNDLFAEF
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_CAMJD
Sequence: MKQKCVLIITDGIGYNKNSKFNAFEAAKKPSYEKLFKEVPNSLLKTSGLAVGLPEGQMGNSEVGHMCIGSGRIIYQNLVRINKAIKNKELEKNENLQKLLAKCKRVHIIGLYSDGGVHSMDTHFKAMLEICAKNGNEVFAHAITDGRDVSPKSGLNFIKDLKGFCENLGVHFATLCGRFYSMDRDKRWDRVKEYYECLLGKAYKVPNLLEYLQKSYDENITDEFIKATQNENYKGMREEDGIIFINFRNDRMKQLVEVLNSKDFKEFEREKVFENLLTMSVYDDKFKLPVLFEKEKIENTLAQVISKAGLSQLHTAETEKYAHVTFFFNGGKEELLENETRVLISSPKVKTYDEKPQMSAFEVCDAVKKGIEKGEDFIVVNFANGDMVGHTGDFNAAIKAVEAVDTCLGEIVECAKKHDYAFIITSDHGNCEAMQDEKGNLLTNHTTFDVFVFVQASGVSKIKANMGLSNIAASVLKILDLEIPKEMNEALF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CNN2_HUMAN
Sequence: MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYPPYYQEEAGY
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
What are the official names of this protein?
Calponin-2, Calponin H2, smooth muscle, Neutral calponin.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: KAD_SHIF8
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_STRPM
Sequence: MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLNRFEDRITICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLTTSTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: GUAAA_METM6
Sequence: MIVILNNGGQYVHRIQRSLKYLEVPAKIVPNSTTLEEIIADSEIKGIILSGGPDITKATNCENIALNSEIPVLGICLGHQLISKAYGGHVSRADSEEYASITIYVKEENDLFKGVPSKFTAWASHMDEVKVTPGCFEILAYSDICGVESIKHKEKSIYGVQFHPEVSHTEYGDVILKNFCKKCGFEFEE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: PYRI_METMP
Sequence: MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEGLELSKDDVNKIALISPDATINIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIESRFSIEQKNTLKIRCEYCEKFINSIIISK
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: URE1_NOSS1
Sequence: MPYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSPIANADGAVDLVITNALILDWWGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEALAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWNMYRMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADEYDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLRAKRYVAKYTINPAITHGIAQYVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGSFAGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSESYEVRADGELLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB1_SULID
Sequence: MVIMGNELQLENKILKGTTTVGIKVNDGVVLAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKV
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.