PharMolix/UniProtQA huggingface dataset:
Protein: RL13_SALTY
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ALR_BORBU
Sequence: MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKNINYFGLSNIEDAKTLKKIDKNIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKECALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFLELEGICSHLPSIENFKTTQKQIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKPALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFYFLINNKKCKIRGKVCMNLTIVEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLCNIGKYEKRKYLD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: TAL_MYCLE
Sequence: MTSKIQNPNLAALSAAGVSVWLDDLSRDRLQSGNLQKLIDTKSVVGVTTNPSIFQKAFANGHAYDAQIAELAKRGANVDVTVRTVTTDDVRHACDVLACEWEASHGKDGRVSIEVDPRLAHDTDKTIAQAVELWRIVDHPNLFIKIPATKAGLPAITAVLAEGISVNVTLIFSVQRHREVIDAYLAGIEKAAEAGRDLSKIVSVASFFVSRVDTEIDKRLEKLGSEQALALRGQAGVANARLAYAAYQKAFEGGQRYQTLMARGAQVQRPLWASTGVKNPDYADTLYVTELVAPNTVNTMPETTIDAVADHGVIRGDTISGTTLSSQKVFDSLVAVGVDLIDVFAVLEHEGVQKFVKSWNELLKETQEQLDSVAK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CROS5
Sequence: MGQKIHPIGFRLGVTKEHKSCWYADKRRYPELLQEDLAIRQHVEKNLSNAGIADIRIERKADQIDLAIHTARPGVVVGRGGSGIEQLRTGLQQTLGENRQIRINVIEVSRVDADAALIAEYITQQLERRVSFRRVVRQAIQRAQRAEVKGIKIQVGGRLNGAEIARTEWVREGRVPLHTLRADIDYAYRTAQTIYGILGVKVWVFKGEIIPGQDEQAMAAPAPTPRKKRRPQQFEDRSNEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYN_DESHY
Sequence: MENTLIKSIYRDTPAYLNQELQISGWVRTLRVSKSFGFIEINDGSFFKGIQVVFEEDLNNFEEIAKVATGSSLIIKGLLVESPGAKQPFELKAQSIMIEGACSGDYPLQKKRHSFEYLRTIAHLRPRTNTFAAVFRVRSLVAYAIHKFFQDKGFVYIHTPIITGSDAEGAGEMFRVTTLDLDALPRTEEGRIDYAKDFFGKETNLTVSGQLNAETYCMAFRNVYTFGPTFRAENSNTARHAAEFWMIEPEIAFADLQDDMELAEEMMKYLISYVLEHAPEEMAFFNEFVDKTLFDRLDNIVNSDFGRLTYTEAIEILQKEKERFEFPVEWGADLQTEHERFLTEQIFKKPVFVVDYPKDIKAFYMRLNDDQKTVAAMDLLVPGVGEIIGGSQREERLDYLEKRMAELGLHKEDYSWYLDLRKYGGTRHAGYGLGFERVIMYLTGISNIRDVVAFPRTVKNADF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKAR_DEBHA
Sequence: MSLCQFVSSISDCRITQALIYGVLFVGVYKITTFTLSVGSLLVDLFVLPAVDFKKYGAKQGKWAVVTGASDGIGKEYAYQLASRGLNVVLISRTLSKLELIATEIETKYKVSTEVIAFDASTDNDANYAKILHTVSNLPVTVLVNNVGQSHSIPVPFLETEDKELRDIITINNTVTLKITQAVAPVIADTVAKENKKVKGLILTMGSFGGLLPTPYLATYSGSKSFLQAWSSALAGELKPQGIDVQLVISYLVTSAMSKIRRSSASIPNPKNFVTSVLNTAGRRCGAQERFATTTPYWTHALMHFGIENTVGVYSKFANSLNFSMHKSIRVRALKKAARANATKTD
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: YNM2_YEAS7
Sequence: MKISLHNKRQRGDQNQNMSVFNVLKPLLKGSNSFKVKLNGFLFNNVSTITIRTLMKTHKGTAKRWRRTGNTFKRGIAGRKHGNIGWSHRSLKALTGRKIAHPAYSKHLKRLLPYH
What are the official names of this protein?
Putative mitochondrial ribosomal protein SCY_4673.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_ARTJA
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCFGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLPPFIVTALVMVHLLFLHETGSNNPTGIPSDPDMIHSHPYYTIKDILGFLVMLTALASLVLFSPDLLGDPDNYIPANPLTTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHMSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILFLMPMISLVENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CH10_STAAN
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10, Heat shock protein 10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGS3_DROER
Sequence: MKLTIATALVGILLIACAHVANGSDCGCPKRTTPKPCTTARPTCAPVTTTTCRPPTTTRCPPPTTTRCPPPTRPAECTATTKRPTARPTTKRATTRRTTVRATTKRATTRRTTKRATTRRTTVRATTKRATTRRTTTKRAPTRRATTKRATTRRNPTRRTTTRRAPTKRATTKRATTRRNPTKRKTTRRTTVRATKTTKRATTKRAPTKRATTKRAPTKRATTKRAPTKRATTKRAPTKRATTKRAPTKRATTKRAPTKRATTKRAPTKRATTKRATARPTSKPCGCKPCGPGGEPCQGCAKRDALCQDLNNILRNLERKVRQCVCGEPQWLL
What are the official names of this protein?
Salivary glue protein Sgs-3.
Protein: DDI1_EMENI
Sequence: MTIELLKSIVESETSIPPSSQRLVYNQQLLGDDSKTLEQVGIGEGDMLGVHVTLRGGAPSVQGQARPTGIGGTSGASHSQQIQQRRQQQINPDPEMIRLHILGDPRVRDAVRQRNPELADVAHDPHRFREVLLTQQRLESQREAEKEARIAMLNADPFNPENQKEIEEIIRQNAVTENLHNAMEHHPESFGRVTMLYIPVEVNGHKLNAFVDSGAQVTIMSPDCATACNIMRLVDSRYGGIAKGVGTANILGRVHSAQIKIGDMFLPCSFTVMEGKHIDLLLGLDMLRRHQACIDLRRGALVIQDQAVPFLGEADIPKHLLEEFEDEPVIKGADGAEVGARTGAVTHQAGGSTPAPGPSSAANATASSSRPAAVHRPSPRWPEASIAKITELGFTREEATRALEAANGDLDGAIGFLI
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS11_CAEEL
Sequence: MEPESILDFHTEQEEILAARARSVSRENQISLAIVLVGSEDRREIKEGIEILEDVVSDTAHSEDSRVCVHYLALAHARLKNYDKSINLLNALLRTEPSNMQATELRRAVEKKMKREGLLGLGLLGGAVAVVGGLVIAGLAFRK
What is the function of this protein?
Involved in the fragmentation of the mitochondrial network (By similarity).  Involved in perinuclear clustering of the mitochondrial network (By similarity).  Plays a role in removal of ultraviolet C radiation-induced mitochondrial DNA damage (PubMed:24058863).  May act, redundantly with fis-2, downstream of mitochondrial fission, before the fission products participate in either mitochondrial homeostasis, mitophagy, or apoptosis (PubMed:24196833, PubMed:18722182).
What are the official names of this protein?
FIS1-related protein fis-1, Mitochondrial fission 1 protein fis-1.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
Protein: KAT2_ORYSJ
Sequence: METISNIFHNDPLPPLGARANQSIKLRKFIISPYDSRYRTWETFLLVLVVYSAWICPFELAYLRNLSWKVSLVDNIIDSFFAIDIILTFFLAYLDQKSYLLVDDPKRIVARYFSSWFLFDVCSTIPYQLLGQIFKKHENGLAYRLLSMLRLWRLRRLSELFARLEKDIRLNYYWIRCTKLISVTLFAVHCSGCFNYLIADRYPNPARTWIGAAIPNYRSQNLWVRYVTAIYWSITTLTTTGYGDLHAENQREMLFSICYMLFNLGLTAYLIGNMTNLVVQGSCRTRNFRDTIHAASQFAARNQLPGHIKDEMLSHICLRYKTEGLKQKETLDSLPKGIRSSIACNLFLPVIEKVYLFHGVSFTCMIQLVTEMEAEYYPPREVVILQNEAPRDVYILVSGAVEERVEIDGTEKVQEVLCNGEIFGEIGVICSIPQPCAFHTIKVSQLLRLNTAVLKNIIKENSDDRRVILNNLSQKMNQDHRFSTEVMEKSLQMMHQHFGEYNRCSALNQDNEKNELKANNGHSMALEWKRVTIHMYSQRNKRPEAPLAKVINLPGSLDKLFAIACQKFNNYRLTKLVNPEFAEIDDITVIRDGDHLFFMEI
What is the function of this protein?
Probable inward-rectifying potassium channel.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization (By similarity).
What are the official names of this protein?
Potassium channel KAT2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LPXK_AZOC5
Sequence: MIGQAPAFWSRRNSLMGWVLSPIGALVGALTLKRMAGPSTGVPVPVICIGNPTVGGSGKTPTALMVLARLQEQGARPFALLRGHGGRLAGPVLVDPQTHTAADVGDEALLLAQATPTVVSRDRPAGAAHAVALGASHVVMDDGFQNPSLAKDVSLLVIDGEAGVGNGRVLPAGPLRAPLAPQLDRADALLVAGGGRCADALGRLAHSHGKVVLRGQVRPDPSVIATLEAGTVLAFAGIGRPQKLADTLAAAGVRIGRLQPFPDHHPYQPSDIAPLIAEAARERWQLVTTTKDHVRLADRRFADMAGAITALPVTMQLDAPEALDDILRLAEARAAARS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: IDHP_MACFA
Sequence: MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQTRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ
What is the function of this protein?
Plays a role in intermediary metabolism and energy production.  It may tightly associate or interact with the pyruvate dehydrogenase complex (By similarity).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], mitochondrial, IDH, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NDK_BACHK
Sequence: MEKTFLMVKPDGVQRAFIGEIVARFEKKGFQLVGAKLMQVTPEIAGQHYAEHTEKPFFGELVDFITSGPVFAMVWQGEGVVDTARNMMGKTRPHEAAPGTIRGDFGVTVAKNIIHGSDSLESAEREIGIFFKEEELVDYSKLMNEWIY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_PSEA7
Sequence: MARICLHAYVGGRVQGVGFRQSTRDEAERLGLDGWVRNLEDGRVEVLWEGEEEQVKALQRWLERGPRRARVAGVEVEALPLQGIAGFIVRR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: LEUD_RHIME
Sequence: MDKFVKLTGVAAPLPVVNIDTDMIIPKDYLKTIKRTGLGTGLFAEARYNEDGTPNPDFVLNKPAYQNAKILVAGDNFGCGSSREHAPWALLDFGIRCVISTSFADIFYNNCFKNGILPIVVSQEDLDKLMDDASRGSNAILTVDLEAQEITGPDGGSIKFEVDAFKRHCLLNGLDDIGLTLEKGGSIDNYEKATAASRPWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RIBA_ALIFM
Sequence: MANVRARIELMVGQKSNIPAEMLSFEGLETEKEHVAVVFNQADKHQSTPLVRMHSECLTGDVFHSSRCDCGEQLEETINRMSESGGIILYLRQEGRGIGLYNKLDAYELQSQGMNTYEANNHLGFGDDLRDFKEAAQMLEALNISKIKLVTNNPKKIEDIKNYGIEIDEVVNTLAHVKQGNEHYLHSKAAHGHKLNFDK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RN170_XENTR
Sequence: MADNQEGRPYFPLDEGSIIEGVSDQVIVVVLLSFVAVGSLLYLLLRNDEQNIHPENQDRVRAVREQLQNEQETPPPPRPQFYSDMTCPVCLQQATFPVETNCGHLFCGSCIIAYWRYGSWLGAINCPICRQTVTLIFPLFQATEQEDSQNILREAIGYNRRFSGQPRSLMDRIMDLPTLLRHAFREMFSVGGLFWMFRIRIVLCLLGALFYLVSPLDIIPEAVFGLLGFLDDFFVLFLLLIYISIMYREVVTQRLYR
What is the function of this protein?
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway.  Also involved in ITPR turnover in resting cells.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF170, RING finger protein 170, RING-type E3 ubiquitin transferase RNF170.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TMFO2_MYCCT
Sequence: MKTIRIIGAGLSGCEAAYYLLKKGYFVELYEIKTIKKNPIQHYDYFCELAYSDSFRSTDLNTSVGTLKKELELLDSLIIKAARYASINQNNELVVNRIEFSKYITNYLKTFNNLKIIEQEYLNIDLNIPTIIAIGPISTPNFLTNLKKLINKENLKLFDTVEPTILKQSINMDICYSLDNNLNYLYCDLNKEQFEKFYNALISAKTFNSPLKNEIELLEKNNYFSIESLAKNKQEFINHFKPINNNAYITITLKKDSVINNLYTIVNFQTNLMWNEQLKVFSLIPGLENLKIMKYGVMHKNNYINTKKLLNLGVQLKTNKNIFFAGQIIGVDGYVESVCSGLISAINLDRYLNNKKMIIPNKNSTIGSLYNYLLKTDSNFSPMRINWALVDMIGGFELSDNSKKIYSKRAIKLIKQYLKKINT
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO 2, Folate-dependent tRNA (uracil-5-)-methyltransferase 2, Folate-dependent tRNA(M-5-U54)-methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_BIFLO
Sequence: MADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVESYVVDARDEFANEYCMKALKANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGCTGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAFAKEHKLPITQTEKSPYSIDQNVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQAIEEMNRRAGAQGVGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRIKRDIDKRWGELVYDAQWFSPATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSLYDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKFGNGIEVPKNTVE
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_FUSNN
Sequence: MKGFLLLLSFMTRIPMPKTDYDEEKLGKSMKYFPVVGIIVGFILLFFCIIFNFILKNISYSAVLPLMIIVVILTDLITTGALHLDGLADTFDGIFSYRSKHKMLEIMKDSRLGSNGALALILYFLLKFILLFSLTIESREAAVYAIITYPVVSRFCSVVSCASSPYARGSGMGKTFVDNIKTCGLIVATVITLLYTIGMLFMPFILFTNYSLPMQFMIRSVLIIVIIVGLLALFAFAFSKLIERKIGGITGDTLGALLEISSLVYIFLFLVIPTFFIG
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_STRA5
Sequence: MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDRAKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKNILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRILTEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGTDKPVLETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ENGB_RUMCH
Sequence: MIIKNASHEITAVKPIQYPVTGFPEIAFVGRSNVGKSSIINTLVNRKSLARVGSTPGKTRQINFFDVNGEFYLVDLPGYGFANVSKEMKASWQNLIETYLYSRKENFLKMVVMLVDIRHSPSKDDIIMYQWLKGFGLDTLIIANKVDKISRGQIHVRINDIRKVLQLDDAEKVIPFSAENRFGLEKVLAEFDNVLSIPGEEQKD
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CRTE_CERS4
Sequence: MAFEQRIEAAMAAAIARGQGSEAPSKLATALDYAVTPGGARIRPTLLLSVATACGDDRPALSDAAAVALELIHCASLVHDDLPCFDDAEIRRGKPTVHRAYSEPLAILTGDSLIVMGFEVLARAAADQPQRALQLVTALAVRTGMPMGICAGQGWESESQINLSAYHRAKTGALFIAATQMGAIAAGYEAEPWEELGARIGEAFQVADDLRDALCDAETLGKPAGQDEIHARPNAVREYGVEGAAKRLKDILGGAIASIPSCPGEAMLAEMVRRYAEKIVPAQVAARV
What is the function of this protein?
Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes.
What are the official names of this protein?
Geranylgeranyl diphosphate synthase, GGPP synthase, Farnesyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: TRMB_RALSO
Sequence: MQPNEQPGTGPADTTLEQQDTAAAEVGHPRRIRSFVRRAGRTSTGQQRAIDELGPRFLLPYAAAPLDWEAAFGRTGARRIFEIGFGMGETSAHIAQLRPDDDFLGVEVHEPGVGALLKLIGERGIGNVRIVSHDAVEVLAQMIPEGTLDGIHVFFPDPWHKKRHNKRRLIQGPFVARLAAHLRPGGYLHCATDWEEYAHQMLEVLSAEPLLENTADGFAPRPDYRPVTKFEKRGLRLGHGVWDVVFRKRAA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: VP3_ROTHL
Sequence: MKVLALRHSVAQVYADTQVYTHDNSKDEYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAIEIQKMDELFTLIRCNFTYDYIDDVVYLHDYSYYTNNEIRTDQHWVTKTNIEDYLLPGWKLTYVGYNGSDTRGHYNFSFRCQNAATDDDAIIEYIYSDELDFQSFILKKIKERMTTSLPIARLSNRVFRDKLFKTLSVNHDKVVNVGPRNESMFTFLDYPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDMYHEKPIVYMIGSAPSYWIYDVKQYSDLKFETWDPLDTPYSNLHHKELFYINDVQKLKDNSILYIDIRTDRGNMDWKEWRKVVERQTADNLYIAYKYLSTGRAKICCVKMTAMDLELPISAKLLHHPTTEIRSEFYLMMDIWDSKNIKRFIPKGVLYSYINNIITENVFIQQPFKLKTLKNEYVIALYALSNDLNNREDVIKLINNQKKALITVRINNTFKDEPKVGFKNIYDWTFLPTDFETSESIITSYDGCLGIFGLSISLASKPTGNNHLFILSGTDKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTGKASIEGGRYYEHAPIELIYACRSAREFAKLQDDLTVLRYSNEIENYINKVYSITYADDPNYFIGVKFKNIPYKYNVKVPHLTFGVLNISEQMLPDAIAILKKFKNELFGMDITTSYTYMLSDEVYVANISGVLSTYFKIYNAFYKEQITFGQSRMFIPHVTLSFSNEKTVRIDTTKLYIDSIYLRKIKGDTVFDMTG
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: KHSE_CHLPD
Sequence: MKTVRGFASATVGNVACGFDVLGFAITEPGDEVILTLHEERKSECPVSITAISGDGGALPLDPKKNTSSFVVLKFLEYIRTSKGIDFKGHIDLELKKNLPLSSGMGSSAASAAAALAAANELLGQPCSKMELVHFAVEGERVACGSAHADNAAPAILGNFVLIRSYAPLDLITIPSPEHLFCTLVHPHTELKTSFARSVLPRSIPLKTATQQWGNVGALIAGLLKSDYDLIGRALVDVVAEPKRAPLIPGFLDVKHAAIDCGALGCSIAGSGPSVFAFSSSKETAERVGQAMREAFLLPETNLKSDMWVSPICKEGAKVL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_BACCZ
Sequence: MNRLKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELMELAEDRIEILSHNRYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLWNLGLTIDQLAELGAEIGSDVSFCVYGGTAIATGRGEQIEHIKTPPSCWVILAKPHIGVSTADVYGNLKLNRVTHPNVDKMVDVINAGDYKGICDTVGNVLEDVTFAMHPEVARIKAQMKRFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLLGERETLE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.