PharMolix/UniProtQA huggingface dataset:
Protein: OSB9_DICDI
Sequence: MTEVQSITTSGEIKMPLSPSSSSSSISSSTTNNTNIKSIPILSQCYSFSGKGNGKELQDKIFRQNSRHSNGGWKFVDDIELKKQRGVCWSLVKSVGNSIIEGKELTSTCLPIELFEARSFLEKVTDTMAFGPLYLKAAAETNDPIERMKMVASFVVSGLHLTTTIAKPFNPLLGETFECDLADGSSAFCEQISHHPPISSWKLLEKDGKYKYTGHFIWSAGCRGNVVKGCLKGPHNIEFADGTNIAFTYPDVLIKGIFWGDRVTEFCGKMLFTDEKNDLACELIFNPNALGFVKSFFSKQKTPCDTIDGRIFRINNNKIKDGNCDKINPDDVLCKMEGTWLTSFLIDQVEYWNIRMIPHGVIYRDPETTLPTDSGRRDDIKHLKMGNLEEAKKYKALIEDNQRKQKKEKDEKLKKDEKLKKEDKKNQK
What are the official names of this protein?
Oxysterol-binding protein 9, OSBPi.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: ABR_MOUSE
Sequence: MEPLSHRGLPRLSWIDTLYSNFSYGAEDYDAEGHEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDSVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEMSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKTKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTTEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVESKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCIEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV
What is the function of this protein?
Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins.  The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42.  Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form.  The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1.  Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (By similarity).  Functions as an important negative regulator of neuronal RAC1 activity (PubMed:20962234).  Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (PubMed:17116687).
What are the official names of this protein?
Active breakpoint cluster region-related protein.
What are the subcellular locations of this protein?
Cell projection, dendritic spine. Cell projection, axon. Synapse.
Protein: PTN6_RAT
Sequence: MLSRGWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATSTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAAPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEAKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNCKEHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGNITYPPALRSAHAKASRTSSKHKEEVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRNISLTPCRGLRWADRDL
What is the function of this protein?
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR.  The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates.  Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 6, Protein-tyrosine phosphatase SHP-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II. Shuttles between the cytoplasm and nucleus via its association with PDPK (By similarity).
Protein: CFAB_PIG
Sequence: AIRCPRPHDFENGEYWPRAPYYNLSDEISFHCYDGYTLRGSANRTCQVTGRWDGQTAICDDGAGYCPNPGIPIGTRKVGTQYRLEDSVTYYCTRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPAEVAEAFLSSLTETIEGVDAEDG
What is the function of this protein?
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.  Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase.
What are the official names of this protein?
Complement factor B, C3/C5 convertase, Properdin factor B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAAL_HALMA
Sequence: MRIEDVRTVPGLSGFFFDDQQAIKDGATQTGFAYDGQPVTDGFDRIREAGEALIVEIELADGSIATGDCAAVQYSGAGGRDPLFRAEKYRPVVEGAVADALRGQDATQFGANATMLEEMSPQRSGGDQLHTAVRYGVSQALLNAAAQARGVTPTDVLADTYDTEPATSPVPVFGQSGDERRINAEKMLIKGVPVLPHGLFNSVEKVGENGEGLRDYLAWLSDRATALGPEPYSPRFHVDVYGILGKVFGPPYDRTEVTDYFETLREAAAPYPLQVEGPMDAGGRQAQITEMAELREGLADAGVDVDIVADEWCNTFEDVQAFVDAEAADLVQIKTPDLGGIQRSAEAVLYCDGTDTRAYVGGTCNETVTSARACAHVALATDAAQVLAKPGMGFDEGFMVVTNEMRRALARRDATQEVPADD
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo-(2S,3S)-3-methylaspartate) to give mesaconate (Probable).
What are the official names of this protein?
Methylaspartate ammonia-lyase, MAL, 3-methylaspartate ammonia-lyase, Beta-methylaspartase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate ammonia-lyase family.
Protein: ASIP_MACSL
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVTTRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_CHRSD
Sequence: MKRTFQPSVLKRKRVHGFRARMATKNGRQVLARRRAKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MERL_HUMAN
Sequence: MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAKSRVAFFEEL
What is the function of this protein?
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis.  Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway.  May act as a membrane stabilizing protein.  May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.  Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin.
What are the subcellular locations of this protein?
[Isoform 1]: Cell projection, filopodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=In a fibroblastic cell line, isoform 1 is found homogeneously distributed over the entire cell, with a particularly strong staining in ruffling membranes and filopodia. Colocalizes with MPP1 in non-myelin-forming Schwann cells. Binds with DCAF1 in the nucleus. The intramolecular association of the FERM domain with the C- terminal tail promotes nuclear accumulation. The unphosphorylated form accumulates predominantly in the nucleus while the phosphorylated form is largely confined to the non-nuclear fractions. SUBCELLULAR LOCATION: [Isoform 7]: Cytoplasm, perinuclear region. Cytoplasmic granule. Note=Observed in cytoplasmic granules concentrated in a perinuclear location. Isoform 7 is absent from ruffling membranes and filopodia. SUBCELLULAR LOCATION: [Isoform 9]: Cytoplasm, perinuclear region. Cytoplasmic granule. Note=Observed in cytoplasmic granules concentrated in a perinuclear location. Isoform 9 is absent from ruffling membranes and filopodia. SUBCELLULAR LOCATION: [Isoform 10]: Nucleus. Cell projection, filopodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Cytoplasmic granule. Cytoplasm, cytoskeleton. Note=In a fibroblastic cell line, isoform 10 is found homogeneously distributed over the entire cell, with a particularly strong staining in ruffling membranes and filopodia.
Protein: ARLY_STRSY
Sequence: MEAKKLWGGRFEASLEEWVEEFGASIRFDQKLAKYDIQGSLAHVKMLGQTRIISQAEAQVIQAGLEELLEEYEAGKLVFDIRNEDIHMNIESLLTEKIGSVAGKLHTARSRNDQVATDMHLYLKDTLFQVVDKLTNLRQILVDLAQEHVETIMPGYTHLQHAQPISFAQHLLAYYNMFSRDSERFAFNMQHTNVSPLGAAALAGTTFPIDRQMTSDLMGFAKPYSNSLDAVSDRDFILEFLSNASILMMHMSRLCEEIINWCSYEYQFVTLSDTFSTGSSIMPQKKNPDMAELIRGKTGRVYGNLVGLLTVMKSLPLTYNKDLQEDKEGMFDTAETVLISIDILAGMLKTMTVHKERMAQSTEKDFSNATELADYLASKGLPFRQAHEIVGKLVLECSKAGHYLQDVSFETYQAISPLIQADIYDALSSKVAVSRRNSLGGTGFESIADQLKSAKEEIQNAKSL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GR22_ANOGA
Sequence: MIHTQMEDAQYEIRHQVLNPNQRQQLEDRRRIKEQLHQLEQDNESPTHMYRRKLKIASDVNLLDQHDSFYHTTKSLLVLFQIMGVMPIMRSPKGVDMPRTTFTWCSKAFLWAYFIYACETVIVLVVARERINKFISTSDKRFDEVIYNIIFMSIMVPHFLLPVASWRNGSEVAKFKNMWTDFQYKYLIVTGKPIVFPKLYPITWTLCIVSWSLSLVIILSQYYLQPDFQFCHTFAYYHIIAMLNGFCSLWFVNCTAFGTASKAFAKELTDVLATERPAAKLTEYRHLWVDLSHMMQQLGKAYSNMYGIYCLVIFFTTIIATYGSLSEIIEHGATYKEVGLFVIVFYCMSLLFIICNEAHHASKRVGLNFQERLLNVNLTAVDKATQKEVEMFLVAIDKNPPTMNLDGYANINRGLITSNISFMATYLVVLMQFKLTLLRQSAKNAFISALKANLSRIRSLDADKVNT
What is the function of this protein?
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.  GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide-chemosensation.
What are the official names of this protein?
Gustatory and odorant receptor 22.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CKB12_ARATH
Sequence: MEKYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPTEQQWPGVMALRDWHVYPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISAKAALDHPYFDSLDKSQF
What is the function of this protein?
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata (PubMed:20675570).  In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248).
What are the official names of this protein?
Cyclin-dependent kinase B1-2, CDKB1;2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: UREF_KLEP7
Sequence: MSTAEQRLRLMQLASSNLPVGGYSWSQGLEWAVEAGWVPDVAAFERWQRRQMTEGFFTVDLPLFARLYRACEQGDIAAAQRWTAYLLACRETRELREEERNRGAAFARLLSDWQPDCPPPWRSLCQQSQLAGMAWLGVRWRIALPEMALSLGYSWIESAVMAGVKLVPFGQQAAQQLILRLCDHYAAEMPRALATPDGDIGSATPLAAIASARHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_NOSS1
Sequence: MLDIKQIRENPQLIQERLNSRNGTYDIQPILQLDKQQRELEATRSQIQARSNEIGKIVGQKIKSGINPQDPEIQALRDEGNAIKAQLSELEPREKELKAEIEQLILALPNLPSDSTPIGKGEEENVEVRLWGDEYLPQNPNIIPHWEIGEKLGILNFERAVKVAQSRFVNLIGAGAALERALINFMLKMQTAAGYIEVSPPLLVNTDSLTGTGQLPKFAEESFKCADDELWLIPTAEVPVTNLYRGEILAAENLPIYHCAYTPCFRREAGSYGRDMRGLIRLHQFNKVELVKVVHPSTSFDELEKLVGNAEAILQALKLPYRVINLCTGDLGFGATKTYDLEVWLPSSGKYREISSCSNCFDFQARRADIRFKEAGKKGTQFVHTLNGSGLAVGRTMAAILENYQQPDGTILIPEVLQPFLGREVL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_VIBVU
Sequence: MRLFILVLTLLFGWLQYTLWFGKNGVSDYYTIESDIEAQQLVNTKLQARNSEMYAEIDDLKQGLDAIEERARHELGMLKEGETFYRIVGEENQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: TTHY_SMIMA
Sequence: MAFHSLLLLCLAGLVFLSEAGPVAHGAEDSKCPLMVKVLDSVRGSPAVNVDVKVFKKTEEQTWELFASGKTNNNGEIHELTSDDQFGEGLYKVEFDTVSYWKTFGISPFHEYADVVFTANDAGHRHYTIAAQLSPFSFSTTAVVSNPKD
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain (By similarity).
What are the official names of this protein?
Transthyretin, Prealbumin.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: H4_FLATR
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMM_PSEAE
Sequence: MSRKYFGTDGIRGRVGEFPITPDFVLKLGWAVGMAFRRQGNCRVLIGKDTRSSGYMFESAFEAGLSASGADTLLLGPMPTPGIAYLTRTFHAEAGVVISASHNPHDDNGIKFFSGQGTKLPDDVELMIEELLDAPMTVVESARLGKVSRINDAAGRYIEFCKSSVPTSTDFNGLKVVLDCANGATYKIAPSVFRELGAEVTVLAASPNGLNINDKCGSTHLDGLQAAVVEHHADLGIAFDGDGDRVMMVDHTGAVVDGDELLFLIARDLQESGRLQGGVVGTLMSNLGLELALQELHIPFVRAKVGDRYVMAELLARNWMLGGENSGHIVCCQNTTTGDAIIAALQVLMALKHRGQTLAEARQGIRKCPQVLINVRFKGENDPLEHPSVKEASVRVTEQMGGRGRVLLRKSGTEPLVRVMVEGDEEASVRAHAEQLAKIVSEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: 3NO22_MICCO
Sequence: MKTLLLTLVVVTIVCLDLGNTANTLFCDNSNVPSIRTRKRCLKNQKLCYKMTFFTPGFGWTQIKGCIHRCPESTPNEKYQCCSTDNCI
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Three-finger toxin 3FTx-2, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MAK16_DICDI
Sequence: MQSDDIIWDVINKNFCSFKTTFNKTKFCKNEYNVTGVCNKVSCPLANSRYATVREEEGVCYLYMKTVERAHTPNRLWEKIKLDPNFMKAIEQIDSHLEFWPGHMSHRVKQRYIRITQYLIRMRKMRKQIKRELVPIKKKAERRDATRENKALIAAHLTTNIKKELLERLNKGTYADMHYFPEDIINNVLEKEGEADQFSEEEADENEEEGEEEMEEEFEDDIDDIEDAGGAFEYVEGDDDEDDIDDEYENEPYQDDDEEDDDDDDDDDEEVKPQITKKRGPTFKPTKKTPQKRVHMEVEIEEETENQAN
What are the official names of this protein?
Protein MAK16 homolog, MAK16-like protein.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSA4_SPIOL
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILAKDGVVLIGEKKVTSKLLQTSTSTEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKNYGFQLYMSDPSGNYGGWKATAIGANNQAAQSMLKQDYKDDVTREDAVKLALKALSKTMDSTSLTSEKLELAEVYLLPSGKVKYQVHSPESLNRLLTESGLTQPAAETS
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-4, 20S proteasome alpha subunit C, 20S proteasome subunit alpha-3, Proteasome 27 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYS_BRASO
Sequence: MHDIKSIRDNPQDFDAALTRRGLSPLSSQLLAIDERRRAAILASEQAQARRNAASREIGEAKKAKDEGRASALMEEVAKLKTTMPELEAAAKQADEELARELSAIPNLPLDEVPDGKDEHDNVERHVFGARRNYAFAPKAHDDIGTALGMDFESAAKLSGARFVVLKKGLARLERAIGQFMLDLHTTEHGYTEVNPPLLVRNDVMFGTGQLPKFEDDQFWAVRGELLIAPDERLKAERLGLIPTAEVALTNLVRESIVDEKELPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPETSKDEHERMLACAEEVLRRLDLHYRVITLCTGDMGFSSQKTYDIEVWMPGQGDGGAFREISSCSVCGDFQARRMDARYRASDGKPRFVHTLNGSGTAVGRALIAVMETYQQADGSIAVPDVLQPYMGGLKVVAADS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_EXISA
Sequence: MDKVFDYEDIQLIPAKCIVDSRSECDPTVELGGFTFRLPVVPANMQTIIDEKVALMLAKNGYFYIMHRFNPETRLAFIQDMHERGLYASISVGVKDEEYGFIEVLKSTGHTPEFITIDIAHGHSNAVIRMIQHIKHHLPGSFVIAGNVGTPEAVRELEHAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAATKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHDESPGETFEQDGKQLKEYFGSASEFQKGERKNVEGKKMFVEHKGALQDTLTEMEQDLQSAISYAGGDSLEALRTVDYVMVKNSIFNGDKVY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: MCRA_ECOLI
Sequence: MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK
What is the function of this protein?
Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence 5'-C(me)CGG-3'.
What are the official names of this protein?
Type IV methyl-directed restriction enzyme EcoKMcrA, EcoKMcrA, 5-methylcytosine-specific restriction enzyme A.
Protein: GATC_PROA2
Sequence: MSVTKKDVAYIAELAKLRFTEAEQEKMTTELNAILHYVDKLNEVDTDGVEPLSSIHDQVNVLREDCLKPSLDNEEALKNAPDRQERFFRVPKVIG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PBGP9_SOLMG
Sequence: MKTFVLHIFIFALVAFASASRDSARKIGSQYDNYATCLAEHSLTEDDIFSIGEVSSGQHKTNHEDTELHKNGCVMQCLLEKDGLMSGADYDEEKMREDYIKETGAQPGDQRIEALNACMQETKDMEDKCDKSLLLVACVLAAEAVLADSNEGA
What is the function of this protein?
Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9.  Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form).  Differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers (By similarity).
What are the official names of this protein?
Pheromone-binding protein Gp-9, PBP, Putative odorant-binding protein Gp-9.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.