PharMolix/UniProtQA huggingface dataset:
Protein: SEY1_PARBP
Sequence: MVANGHFAGVGDVLDAKNYEHGVQVIDEEKEFNPNLSNYLSYENVTPAGFNYHLISVFGSQSTGKSTLLNSLFGTHFSVMSETERRQTTKGIWLSKNKRLKSDKGQDNQTKMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLELFLKDKRSNPRSLLFFVIRDFLGTTPLQNLQNTLLQDLNRIWNSLSKPAGLENSSITDYFDFAFAGLPHKNFQPEKFVDEVRKLSTRFCDGHRDPNKTDAKGTSSIEGGIFLPEYHRRIPADGFAVYAEGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVLVAFDEAISPFEAKQAEAVQAGNPQVLGGLGSAMCNARMKSVKNFDTEASRYHKRVYQMKKSELQDKIDSRLKALFLGQLSAAHRSGIQEFTESVTAAVKAGQKRGASYDFAEIVTKERKLAIEKFEKEARAAVVEDTQWSNYQQELSLYQKDLENIGGQLRRDEMRRLATRVGRWVRSRLGESIDLEFNAIGSGRGGSGAPEFGDKPSEKSLWDRVWTLFVDTVLDAERRFTERASSFDASIDEVDVGLWRLRRKSWGVLRAKIEEEMMEGNILLKLRENFEDKFRYDDAGVPRIWRPNDDIESIYTRARESTLTLIPLLSRFRLAETNAPPPLDKWIGHTPSSATPADEEDLTPIGGVDEDEGKSLEEEMTMIGEAKKQDLTVRFKKTADGVYVEAKRSAIGGITQVPLYFYGLLLALGWNEIVAVLRNPAYFLLLFVCAVTAYVTYQLNLWGPIIKMTEAASQQALMEGKRRLREFLEASDTGLQAMAMSEGRNAEEYDMSNMKNRKSAGGFQNNRSHIDDADDDDDF
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: RL29_SOLUE
Sequence: MKAQNVRDLDEHELKTKLKEMDEQMFRLHFQMSMGQMDGLKKVRQMRKDRARMNTILRERELAGEKK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RIMP_RUTMC
Sequence: MARVTDKITHLIELVIKDMCYELVGIEYVASGKHSILRVFIDTDKKGVGVNDCEKVSRQLSSIFDVEEPISGQYTLEVSSPGIERPLFHKEHYQRFLGANVKLRMVRPIDGRRNFFGVIGCVNEADNTFELVGELDLVILDIDLIEKANLVVDF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGPRT_STRP8
Sequence: MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKGSVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDIIDTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDYAENYRNLPYVGVLKEEVYSK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGFD2_DANRE
Sequence: MERFYTCSCFFTDNIFLEEYKLHVRFVSENQFRKDYQNILRSLGCESESQFRDVIGKIQAEIERRQNHKLKSTERAAVIKEIYTPLHQHVYHLQESFLAPELLEMVKYCASSEANVQGLLKLIQTEAASRVFRFQVFRKEFCKDLLEELEHFEQSDAPKGRPNTMNNYGIVLNELGFDEGFITPLREVYLRPLTALLYSDCGGNCLDSHKAFVVKYDMHEDLNLSYHYDNSEVTLNVSLGKDFTEGNLFFGDMRQVPLSETECVEVEHRVTEGLLHRGQHMHGALSISSGTRWNLIIWMRASRQRNKLCPMCGKRPTLVESDGFSDGFTMDSDGDARANVSCSLT
What are the official names of this protein?
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the OGFOD2 family.
Protein: UPP_AGRFC
Sequence: MDGVTVIEHPLVRHKLTIMRKKETSTAGFRRLLREISTLLCYEVTRDLEMTMETIDTPLETIQAPVLEGKKLVFASILRAGNGLLEGMLELVPSARVAHVGVYRDHDTLEAVEYYFKAPESLDARLVIVVDPMLATGNSSIAAVEKLKERGAKNIRFLCLLAAPEGIKNFREAHPDVPIYTAAIDRHLNEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ADD1_STRCO
Sequence: MTSRSTEKSAAANPAAVSKTPSPDRIRRAPKVLLHDHLDGGLRPGTIVELARETGYGDLPETDADLLGTWFRQAADSGSLERYLETFSHTVGVMQTRDALVRVAAECAEDLAEDGVVYAEVRYAPEQHLEKGLTLEEVVEAVNEGFREGERRARDNGHRIRVGALLTAMRHAARSLEIAELANRYRDLGVVGFDIAGAEAGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIQVHEDGSVKLGRLASYVRDKRIPLELCPSSNLQTGAADSYAEHPIGLLRRLHFRATVNTDNRLMSHTSMSREFEHLVEAFGYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAELKSEWLFQQTASTSGSSESDG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase 1, ADA 1, Adenosine aminohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: TUSA_HAEIG
Sequence: MSEISVTQTLNTLGLRCPEPVMLVRKNIRHLNDGEILLIIADDPATTRDIPSFCQFMDHTLLQSEVEKPPFKYWVKRGK
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_RENSM
Sequence: MAKIILTHEVTGLGAAGDVVEVKNGYARNYLLPRGFALTWTKGGEKQVESIKAARAAREHASVEAAQAQAAKLSSTPVRLEVKAGDSGRLFGTVKAEDVAKAVEAAGLGSIDKRKVEIPAHIKSVGKYQANVRLHEDVSAVIDLNVVAGK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: HDAC9_CHICK
Sequence: MHSMISSVDVKSEVPVGLEPISPLDLRTDLRMMVPMVDPIMREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQELERHRREQQLPPLRGKERGRERAVASTEVKQKLQEFLLSKSATKDSPANGKNHSVSRHPKLWYTAAHHTSLDQSSPPLSGASPPYKYTLPGSQDAKDDFPLRKTASEPNLKVRSRLKQKVTERRSSPLLRRKDGNVVSSFKKRLFEVTESSVSSSSPGSGPSSPSNGPTSSITESETSVLPSSIQAEHLVSQQRLLIQDESVNLLSLYTSPSLPNITLGLPAVQSQISASSSFKEKQKGETQTLRPGVALAGQYGGNLPPSSTHPHVALEGKPNSSHQALLQHLLLKEQMRQQKLLVTGAVPLHPQSPLAAKERGSPGVRAAHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKMLSKSIEQLKQPGSHLEEAEEELNGDHSMQEERAPASSASIRAESSSAGEDDRIGQQVGAVKVKEEPPDSDEDTQTQQMESGEQAAFVQQVIGKDLAPGFVIKVII
What is the function of this protein?
Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting other histone deacetylases.  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Represses MEF2-dependent transcription (By similarity).
What are the official names of this protein?
Histone deacetylase 9.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOBA_ACIBT
Sequence: MNKGYPVTDLVILAGGQARRMNGLNKLLQQFDGDTQLLKIHQKLKSSVSEIWVNSHRDYSIYQSIVPDIKCFQDDASGFFGPLMGMKSAWSHVKADYVLFIPCDVTYIPTQVVAKLHSALRKNKQAQAAYVSINGDALYPFCLLKRESLEVLEQQIDKQQLSLKNCFKLLHAQVAIFQKQNLFFHSINSLDELQQYKQIKAFKEIFSTN
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C170B_HUMAN
Sequence: MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDLGSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKRSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSNTRRRQQGSDYTSTSEEEYGSRHGSPKHTRSHTSTATQTPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQSPPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI
What is the function of this protein?
Plays a role in microtubule organization.
What are the official names of this protein?
Centrosomal protein of 170 kDa protein B, Centrosomal protein 170B, Cep170B.
What is the protein family that this protein belongs to?
Belongs to the CEP170 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DNAJ_HALS3
Sequence: MSEDFYDVLGVSRDATEDEIMQAYRDQVSEYHPDVSDDPDAEEKFKKIQKAKDVLTDEETRQQYDQLGHERFEEAEKRGATGNGGGGAGGMGGAGGPFGGGMGGGAGGGMGDIFEQFFGGAGGGGGRGRSGPEQGRDLRTDLTVTLSEAYRGVSKQVTVRRPESCADCGGSGYPEDADVRTCPQCDGQGVVTQVRQTPLGRVQQRQECSRCGGEGELHSETCSTCGGQGQTRERATLTVDIPEGIRTGQTLRMDGEGAPGEPGAPNGDLLVDVTVEEHPDFERDGDDLHHRHAVSFPQAVFGAEIEVPTLDGAATFDLDAGTQSGETFRLKGKGMPRLRRRGNGDLYVTVQVVTPESLSDEQRDALEQFAEAGGEEIDVEQGFFEKLKNSF
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CLOBA
Sequence: MGNFKIHSKFKPTGDQPKAIETILKSIKKGNEFQTLLGVTGSGKTFTMANIIEKLQRPTLILAHNKTLAAQLCSEFKEFFPENIVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIVASVSCIYGLGNPDEYKKLTISLRKGMQKERDEIIKKLIEIQYERNDIDFSRGTFRVRGDLLDIIPSSTSSKGIRIEFFGDEIDRIREFDVLTGTILGERNHVLIFPASHFATSKETVERSLGEIENELENRLRELNSQEKLLEAQRLRQRTNFDIEMIREMGYCSGIENYSRILDGRAPGTPPKTLIDYFPEDFLLFIDESHVTLPQVRAMYAGDRSRKNTLVDYGFRLPCAYDNRPLKFEEFEKKINQVMFVSATPAQYELEHSQSIAEQVIRPTGLLDPEIIIKPVKGQIDDLYTEIQETISRGYRILITTLTKRMAEDLTKYMIELGVKATYMHSDIDTIERMKIIRDLRLGEYDVLVGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNSESKVIMYADNITKSMKKAISETERRRKIQTEYNEEHGIIPQTINKEVRDLIEATKVAEESTEYGIEATKSLTKKEVKKLIKEYTEEMMLAAKNLQFERAAQLRDEIEELKGKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_SHESA
Sequence: MRIALGIEYDGSGYFGWQRQAEVDSVQGQLEQALSKVANEPISLFCAGRTDAGVHATGQVVHFETNAIRNEGAWTLGVNANLPDNIAVRWAKEVDDTFHARFSATARRYRYVIYNHNFRPGILRHGVSHYHGDIDTDKMHVAAQALLGEQDFTSFRAIQCQSKTPFRNVHSVKVTRQGMYVIVDISANAFLHHMVRNIVGSLLEIGLGNQPLTWMADLLALKDRNQAAATAKPNGLYLVDVTYPEQYQLPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CUTA_ECOL5
Sequence: MLDEKSSNTTSVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMBI_SHEEP
Sequence: MDRHSSYIFVWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQNTNSPLTHGCLDSLASTADICQARQARNHSGSPLPSLECCHEDMCNYRGLQDVLTPPKGEASGQGNRYQHDGSRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKRLQEQRQQMLSRLHYSFHGHHSKKGQVAKLDLECMVPVSGHENCCLTCDKMRQADLSHDRILSLVHWGMYSGHGKLEFV
What is the function of this protein?
Negatively regulates TGF-beta signaling.
What are the official names of this protein?
BMP and activin membrane-bound inhibitor homolog.
What is the protein family that this protein belongs to?
Belongs to the BAMBI family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LV545_HUMAN
Sequence: MAWTPLLLLFLSHCTGSLSQAVLTQPSSLSASPGASASLTCTLCSGINVGTYRIYWYQQKPGSPPQYLLRYKSDSDKQQGSGVPSRFSGSKDASANAGILLISGLQSEDEADYYCMIWHSSAS
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 5-45.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ATPD_RICRS
Sequence: MNKGNLIKNYAVALFNNAIVDNIQDKIFEEITSINRIITDNFDIREFLFSPIVNKNDKINAVNSLAKNIKISTIVQNFLLLLVKNSRTAILSNIVDAYNTLLYESKNIKIVQVISANKLQPKEQEWIKSRIEKELNQKTEILFDIDNTIIGGIVIKYDSMLQDYSIKGSLEKITKALKTVNIAV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROE_SHESM
Sequence: MTDMPSVTTPALDRYAVFGNPIGHSKSPIIHGQFASLTLQPLSYEAILAPIDGFEASLRAFFQAGGKGANVTVPFKEQAFALCDSLSAEATLAGAVNTLSLLADGTLYGDNTDGLGLVADLLRHLGSLQHKRVLLVGAGGAARGCILPLLKAEVGQLVITNRTQSKAQALVEIFSQVQQGRYSDKLQAMSMPELSGEFDLVINSTSASLAGELPPLPQSIIGNKTACYDMMYGAKPTAFNQWAVQQGAAQVIDGLGMLVGQAAKSFALWRGVEPDTSGVLKLLRDKLQADAQ
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL34_GRABC
Sequence: MKRTYQPSKLVRKRRHGFRARMATVGGRKVIANRRSKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GUAA_STAAB
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIGEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINTKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ZFP42_HUMAN
Sequence: MSQQLKKRAKTRHQKGLGGRAPSGAKPRQGKSSQDLQAEIEPVSAVWALCDGYVCYEPGPQALGGDDFSDCYIECVIRGEFSQPILEEDSLFESLEYLKKGSEQQLSQKVFEASSLECSLEYMKKGVKKELPQKIVGENSLEYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARKKPPINKEYDSLSAIACPQSGCTRKLRNRAALRKHLLIHGPRDHVCAECGKAFVESSKLKRHFLVHTGEKPFRCTFEGCGKRFSLDFNLRTHVRIHTGEKRFVCPFQGCNRRFIQSNNLKAHILTHANTNKNEQEGK
What is the function of this protein?
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency.  Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST.  Binds DXPas34 enhancer within the TSIX promoter.  Involved in ES cell self-renewal (By similarity).
What are the official names of this protein?
Zinc finger protein 42 homolog, Zfp-42, Reduced expression protein 1, REX-1, hREX-1, Zinc finger protein 754.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGC_SALAI
Sequence: MGIRVAVVGASGYAGGELLRLVAGHPEFELVTATAHSQAGHRLHTVHPQLIGLDLVLAETDPAALADADLVFLALPHGESAALAAQLPPKTRVVDLGADHRLADPYAWANYYGGTHAGQWTYGLSELPGQRERVAAATRVANPGCYATAIILALAPLIAAGAAQPADVVVVAASGVSGAGRAAKAHLLAGEVMGDLSPYRVGAHQHVPEIKQATGATSLSFTPVLAPMPRGILATVTAVPARGVDPQAVLAEAYADAPFVHVLPEGRWPHTAATLGSNSCHLQATVDVDAGRLIVVSGLDNLGRGAAGQAVQNANIMVGLPETTGLSAWGVTP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT1_CRYNJ
Sequence: MAETLEEWISDSNQVLNLQMVRTPEDASLLQYEEQQNIDVFNPAFTYPIFGDNEKIFGYKGLDIKLHFASGSLRQYLDISYDAKLASSTTPPDEIEGALYKFIPPDYTKSEVEFQKRVAGDAETFKPLGEKIGSYAHPSAGRKGKGQGDSGMAAGKAIEDNEDVVEYEMYKATWSTPGFREYHRRMQIFVLLFIEGGSYVHEDEDAWEFIVLYERRTRPDSGIFTYHFVGYVSVYPFWCYPDRVRLRLSQFVILPPYQHQGHGSKLYNMLFRHMLDRSEVAELTIEDPAEAFEDLRDRNDLRFLVKEGIVKDPMLYVDVGKGKRGSRVEWELAIRRKYKIAQRQFDRLLEMLLFRQLDKGNPDKVKAYRLHVKARLYRFNYEMLSQMTVEERKEALAKTYESVVEDYKRILGMTFG
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair (By similarity).
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LRGA_BACHK
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDEKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.