PharMolix/UniProtQA huggingface dataset:
Protein: SYAM_DICDI
Sequence: MIRSSIKNKITTTKSLSCISLINRQYGTSTKEVRETFLNYFEKNGHKRLPSGSLLPYNDNSLLFTNAGMVQFKNQFTGNEESKYKKVTTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGGYNHFKRDSIQHAWDLLTKEYGLPKERLAISVLEGDEESAEIWRNQIGLPNDKIMYKGREDNFWSMGDGPGPCGPCSEIFWDHGKEVDGERYLEIWNLVFMQYNKSGKEGDEMPVDKLPIPCVDTGMGLERMASVLQGKFTNYDIDLFQNLINSFKEIVTMDVGRAQFQLQQDPQRVETAYRVIADHLRSISFLISDGVIPFNIGRGYVLRKIIRRALSYGKILGFNGPFLSTLFPLLEREMGDIYPQLIERSNEIRNVILNEEGTFYNAIQRGIPYLEEFVQQNKLNEESLFLLYNTYGLPLEMSQVKAKQNNIEIDMDKVNKLIDETREQSRLTWNTSSSSSDQTTQQTTQLPEKTFLSWKSDNIKPKFIGYNGCVENDNSKVLRSHFDNDSHLVYLSLDETPFYGTSGGQVGDVGELINVSSGKNVYRVINTIKPYEGGLVLVVEWDPSQQLASQVYQDLKQDSLLNCRVDRSIRNQVAVHHSATHLLHAALRNVIGKSVVQAGSLVGSESLRFDFTHGQKLTPNQIEQIEQWVNDAIAKDIALNTDEIPYEQASKNSDTLQLFSEKYSELVRVVSIPGFSKELCGGTHVERSSSIHQFKIISESSVAAGTRRIEAVAGLAATNFFKNHYQLVHQLSNSINSPIVNFQQSFERLVNTNSKQEKEIFDLKLKIAQLSSVNYNGQYKSDNGGEMIPLSLHIIDCEDKKAFTKVTENFAKEFSSSPIQLTISKGGKVLCQLLSSSSSSSSSLSADTVLKQLFKSIGMGKGGGNKLMANASIQPLNNEILNSILNWSNVNNNYNNKKN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, mitochondrial, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UBS3B_MOUSE
Sequence: MAAREELYSKVTPRRDRLQRPGTVKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTVSSSSLAFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPVSKLAISESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE
What is the function of this protein?
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases.  Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface.  Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70.  Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
What are the official names of this protein?
Ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein p70, Suppressor of T-cell receptor signaling 1, STS-1, T-cell ubiquitin ligand 2, TULA-2, Tyrosine-protein phosphatase STS1/TULA2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FDHL_STAAC
Sequence: MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGPIQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVCDYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDIEVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMTDTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVWTKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEALNVIADNFTAIKEKHGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQAPATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIHVFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIDEWVDDFDEYYKSLETFTMAFAEEATGIPESELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNLLLVTGNYRRPGTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVKLNPKAGKDNHEMVEGIHDGEVHSLYLYGEDTGIVDSNINFVQAAFEKLDFMVVQDEFLTFTATYADVVLPASPSLEKDGTFTNTERRIQRLYQALEPLGDSKPDWKIFQAIANRLGFDWNYKHPSEIMDEVARLTPLYAGVSYDRLEGFNSLQWPVQPDGTDEPILYLEGFNFDNGKAKLFPLSFDNYFKQDEIYDIHVNNGRLLEHFHEGNMTYQTPMIKYKVPRAFVEISPELAEDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINLLTNSDVDQYTDTPSYKRTSCRLEVITKRGKSPLNPNNFRVNKKRQPQYSVQVQKKWERSDYVFPGNQVDK
What are the official names of this protein?
Putative formate dehydrogenase SACOL2301.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: EX7S_NEIMB
Sequence: MKKNAPKSFEEALSRLESLTQSMQGEMPLEDALAAYQEGNELVRYCQTKLAQVEQKLQVLDTDGLKELNLESDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCR1_EMENI
Sequence: MFSRYAFRCAQPLRQSARQYSTEAPKSKSLAPVYVAVGLAGLGVGLYRYQSGAATAEAPAERPKVFTGGDQGWVNLKLSDIEILSHNTKRLRFEFPDKEAVSGLHIASALLTKYSPPDGSKPVIRPYTPTSDEDQPGYLELVVKRYPNGPMSEHLHNMNVDQRLDFKGPLPKYPWEANKHKHICLVAGGTGITPMYQLAREIFKNPEDKTKVTLVFGNVSEEDILLKREFEDLENTYPQRFRAFYVLDNPPEGWTGGKGYITKELLKTVLPEPKEENIKIFVCGPPGMYKAISGPKVSPKDQGELTGILKELGYSKDQVYKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PSAK_CUCSA
Sequence: WDYIGSPTNVIMVISTSLMLFAGRFGLAPSANR
What are the official names of this protein?
Photosystem I reaction center subunit psaK, chloroplastic, PS I subunit 12, PSI-K, Photosystem I 4.5 kDa protein, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DXS1_ORYSJ
Sequence: MALTTFSISRGGFVGALPQEGHFAPAAAELSLHKLQSRPHKARRRSSSSISASLSTEREAAEYHSQRPPTPLLDTVNYPIHMKNLSLKELQQLADELRSDVIFHVSKTGGHLGSSLGVVELTVALHYVFNTPQDKILWDVGHQSYPHKILTGRRDKMPTMRQTNGLSGFTKRSESEYDSFGTGHSSTTISAALGMAVGRDLKGGKNNVVAVIGDGAMTAGQAYEAMNNAGYLDSDMIVILNDNKQVSLPTATLDGPAPPVGALSSALSKLQSSRPLRELREVAKGVTKQIGGSVHELAAKVDEYARGMISGSGSTLFEELGLYYIGPVDGHNIDDLITILREVKSTKTTGPVLIHVVTEKGRGYPYAERAADKYHGVAKFDPATGKQFKSPAKTLSYTNYFAEALIAEAEQDNRVVAIHAAMGGGTGLNYFLRRFPNRCFDVGIAEQHAVTFAAGLACEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFAMDRAGLVGADGPTHCGAFDVTYMACLPNMVVMAPSDEAELCHMVATAAAIDDRPSCFRYPRGNGIGVPLPPNYKGVPLEVGKGRVLLEGERVALLGYGSAVQYCLAAASLVERHGLKVTVADARFCKPLDQTLIRRLASSHEVLLTVEEGSIGGFGSHVAQFMALDGLLDGKLKWRPLVLPDRYIDHGSPADQLAEAGLTPSHIAATVFNVLGQAREALAIMTVPNA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).  Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development (By similarity).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 1, chloroplastic, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SIX1_LEIQU
Sequence: KKNGYAVDSSGKAPECLLSNYCYNECTKVHYADKGYCCLLSCYCVGLSDDKKVLEISDARKKYCDFVTIN
What is the function of this protein?
Excitatory insect beta-toxins induce a spastic paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  In vivo, this toxin induces a fast excitatory contraction paralysis on fly larvae (PubMed:2311768).  It is active only on insects (PubMed:2311768).
What are the official names of this protein?
Beta-insect excitatory toxin LqqIT1, Insect toxin 1, LqqIT1'.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2292_MYCBO
Sequence: MANDARPLARLANCRVGDQSSATHAYTVGPVLGVPPTGGVDLRYGGRAGIGRSETVTDHGAVGRRYHQPCAGQIRLSELRVTILLRCETLCETAQLLRCPPLPCDCSTPL
What is the function of this protein?
May play a regulatory role in sulfomenaquinone (SMK) biosynthesis.
What are the official names of this protein?
Uncharacterized protein Mb2292c.
Protein: PDXS_ALKCK
Sequence: MEKVVGTDRVKQGMAQMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARMADPTVTEEVLNAVSIPVMAKARIGHIVEAKVLEAMGVDYIDESEVLTPADEVYHLNKRDFTVPFVCGARDLGEAARRIGEGASMIRTKGEPGTGNIVEAVRHMRKMQAQIKQVAHMSTDELMTEAKQLGAPYELLLHIKETGQLPVVNFAAGGIATPADAALMMHLGADGVFVGSGIFKSDNPEKFARAIVEATTHYTDYERIAELSKNLGSAMKGIDVATLAPAERMQDRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: COX3_TRASP
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMILLMLGLTTNMLTMYQWWRDIIRESTFQGHHTPVVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLDPLEVPLLNTSVLLASGVSITWAHHSLMEGHRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGTTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU4LC_ORYSA
Sequence: MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LEC1_CYTSE
Sequence: LNDHLSFNFDKFVPNQNNILFQGEASVSTTGVLQVTKVSKPATRSIGRALYAAPVHIWDSTTGRVASFETSFSFVVKDEPEKSNGVDGLTFFLAPANSQIPSGSSAGLFGLFNSSDNKSSNQIIAVEFDTYFGKTYNPWDPDFKHIGVDVNSIKSIKTVKWDWRNGEVANVVITYRAPTKSLTVSLSYPSDQTSNIVTASVDLKAILPEWVSVGFSAGVGNAAEFETHDVLSWYFTSNLEANPA
What is the function of this protein?
Di-N-acetylchitobiose-binding anti-H(O) lectin.
What are the official names of this protein?
Anti-H(O) lectin 1, Anti-H(O) lectin I, CSA-I.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: RL3_CAMJE
Sequence: MEYIVEKIGMSRTITNPSIAVTLLRVVNAKVCEVEGGKALVAYPKGKASNKCVAGQQKKYNLSAEYNRFATLEVANTEAGDLDETPLNEAKILKVSFNTKGRGYSGVMKRHNFAGGPASHGSRFHRRHGSIGNREWPGRVQPGMKMAGHYGNTKVTIKNEVVSYDAENKILVVKGAVPGYNGAMGKIRIAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TIG_HELHP
Sequence: MNFTTKRINSANAVINGSIALSKIEEKFEKVIKKIAKNIKIDGFRKGKVPTQVIKTRYKEQIDQDAQQEAIQELLTAALKELEIQPNSLIGNPMISQFNKLNDKIELEIKLGITPTLNLDNVEDYTPEVKLKTISKNLIDERLEEIAKNRAPLNEITQERTLQKDDTAQIDFEGFVDGKAFEGGKGENFNLAIGSNQFIPGFEDALIGMKNGEKRTIKVTFPEQYQAKHLAGKEASFDVTLHKILQKELPKIDDEFAKSIAGEESNLQSLKDMIKEQLEMEQKTEIYNKELKEKLVEILLKNISFDLPDLIVEQEMDILFRNALSQLKPEEFDKIKNNQDEAKKQRETHKDEARKSVQITFIMDALAKKYNIAINDNEVLQTIYYEAMMMGQDPKATLEHYQKNNLVPAIKMTMLEDRVLHYLLDKKFEESKANTNAQKDNQ
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DNAG_NEIMA
Sequence: MIPSDFIDELLAKTDIVDIIDEQVPLKKGGANYMACCPFHKEKTPSFSVSPTKQFYHCFSCGAHGSAIGFVMEHQGLSFPEAVQFLADRVGMVVPKVHGQNDNPEVRAERKKKQQTLEETTAAAADFYAQQLKFNPAAKAYLDKRGLSAEVIAHYGLGYAPDGWQPLTQVFQPYPNTALVDTGMVIDNEGRHYDRFRHRIMFPIRNPRGQVIGFGGRVLDDSKPKYLNSPDTPLFDKGKNLYGLYEGRAAVKEAGRILVVEGYMDVVALAQFGVGYGVAALGTATTAEHVKILMRQADSIYFCFDGDSAGRKAAWRALENALPQLKDDKSLHFLFLPEEHDPDSYIRAYGKAQFEDALLNQSKPLSEYFWEHLSDGIHLNTQEGKAELVKTSSPLLAQITAPALAYLLKQRLSELVGIDPDNLAQLLGQEAPKRHVKQKNYKLPPISVKQPVMPTLVQRQIRSLLINPDWAAYIDLPDYLALDGDFACLANLAETIKNHPSVPATAQVLEHMRGSPYEETINRIFRSALQSEEMEGGGEEDCENFQIGIKKLLNELKYSQIEALKQKSLQSGLNESEKKLLLSLLTAKQN
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: ALR_VIBA3
Sequence: MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARIEEALQLRAGGIVKPILLLEGFYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVWLKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHFGCADELDRATTVEQTELFLSLTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHLIAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRVSMDMLTVDLGPDAADKVGDEATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: VATE_SULAC
Sequence: MVDFEELLSKTQEVEKKKIDEELKKAFTEANLIVDEAYNEILSEYSKRIQEIISKNIEALRGEEAKLEVETKRAVNKEKDYWVQQVFQKTLDELEKIANTKDYKNRIESILSRELTEGAIVYCSNNDKKFIEGILTTKRINNVSVEVDNSIKGGVKIYYPDKKLTRDFTLKTILNQIFEDLRDDVARILFGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: UVRC_DESAP
Sequence: MEPAEKVKHFPDKPGVYLFRGARGEVLYVGKAVSLKNRVRSYFTGARSDKVQALVGKTRDVECLVTGSEIEALILESNLIKEHRPRYNVVLKDDKSYPYLKVTVQEEYPRIFLTRAQPRDGARYFGPYPSAAAVHETVRLLKKLFPLRSCRQTRFRQQRPCLNHHIGRCLGPCSGTVDPERYRAMVQEVLLFLEGRHADLVRGLARKMEAAAANLEFERAAELRDQLRAVEQVLARQSIVSPGREDRDVLALARDGNRGRVIVLEIRDGKLLGRHSLDLQGIAERSDAEVLAAFLKQYYREAGLIPPEVLLPVPLGEEQGLIAEWLGLRRQGRVRLHVPRRGRKRELVRLAEQNAAEARAQMEFERDAGEALAELAAVLGLDQAPARLEGYDISNLQGAQTVGVMVVFEDGRPAPGEYRQFRVRETAGTPNDFAAMREVVARRFARAREEGKLIATGRLSSRDARFHRLPDLVLVDGGKGQLSAALEGLRETGFEAVPVFALTKEEEKIFAPGRSDPVPVPPGSQALFLLQHLRDEAHRFAVDTHRRTRSRESLRSLLEEIDGIGPARRRALQKAFPSLDALKGATLAELAAVPSMNRKAAQAVYDYFQDTPTE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_HELPG
Sequence: MEQEICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYEIISLDFLENITRSALFKNSNDLMGYSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCDECPACQLRKKGYEEFQANKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PA_I79A7
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCCQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEPRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIAGMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMILRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: FPR2_GORGO
Sequence: NFSTPLNEHEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERQKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAASCASPPAETELQAM
What is the function of this protein?
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (By similarity).  Binding of FMLP to the receptor causes activation of neutrophils (By similarity).  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).  Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).
What are the official names of this protein?
N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Associates with APP at the cell surface and the complex is then rapidly internalized.
Protein: ATPA_GLOVI
Sequence: MFTIRPDEISSVIRDQIQKYNTELQVTNVGTVLQVGDGIARVYGLEKCMASELLEFEDGTIGIALNLEEDNVGAVLMGAGRTIEEGSTVRATGRIASIPVGPAFLGRVVNALAIPIDGKGDIVGSETRLLESPAPGIIKRKSVYEPLATGITAIDAMIPIGRGQRELIIGDRQTGKTTIAIDTILNQKGKGVVCVYVAIGQKASTVAQIVEVLRSRGALEYTIIVAANANEPAALQYLAPYTGCTLGEYVMYNGLTLPGSDKKINAALLVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPDLGEGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDSGLFNSGLRPAIDAGISVSRVGGAAQTKAMKKVAGKLRLDLAQFSELEAFSQFASDLDKATQAQLARGLRLREILKQPQYSPLSVAQQVAIIYAATNGYLDDIDVKGIQPFKQQFLNYLDSSVSEYGQEIETTKALTDKAVDLLKKALNDFKTTVKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS9_ECODH
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ECOT_ECOBW
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.