PharMolix/UniProtQA huggingface dataset:
Protein: FUTB1_CAEEL
Sequence: MRNVKGLFSYMTKTKSFYISIIVIIFIIFIVNRMGPRNYNYKQIGTEINCVKHKVDEQRYLLFPMITILYKYGLGNQLFEVFSLLGSAQTLNRTAIFNADDDILQSKLDLLQKQVPQVAARIISIPIEIAESTRYLFLPACCHYQFPSLFSCERSKFLVIDGQYFQSFKYFSAIDSLIRKLLKPPIDEEIILKKMIGRKDELRFKNCVHIRRGDYVNDFDHAETSSYFTIRAIDYVHTLHPGLVYLISDDPKWVRKQIAEHLDYHDDVKIMETPINAAIRDLYFSQAHCDSVLITAPSSTFGWWIGYMSKNQSNVYYRDIQETDDMVKYKMVEEDFFPPTWKKLGMSRNGSIISK
What is the function of this protein?
Selectively catalyzes the addition of fucose in alpha 1-2 linkage to Gal-beta-(1->4)-Xyl-beta-R, Gal-beta-(1->6)-GlcNAc-R, Gal-beta-(1->3)-Gal-beta-(1->4)-Glc and Gal-beta-(1->3)-Gal-beta-(1->4)-Xyl-R acceptors but not Gal-beta-(1->3)-GlcNAc-beta-(1->3)-Gal-beta-(1->4)-Glc.  Unlike in mammals, unable to fucosylate Gal-beta-(1->4)-Glc-beta-R.
What are the official names of this protein?
Galactoside 2-alpha-L-fucosyltransferase, Alpha-(1,2)-fucosyltransferase fut-2, Fucosyltransferase fut-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: ATPD_ERYLH
Sequence: MDISAGIQASLAGRYASALFELAAEEGVVTAVESDLDKLHAALGESDDLKAVTNNPEISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKLGDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKLTAREGRTVKLSPTVDPDLLGGLVVTIGSKRIDGSIRTRLNTLANAMKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: 2ABA_SCHPO
Sequence: MDDIEDSLDQWKFAQCFGDKGDVEDITEADIISAVEFDHTGDYLATGDKGGRVVLFERNHSKKGCEYKFFTEFQSHEPEFDYLKSLEIEEKINKIRWCKRTNRAHFLLSTNDKTIKLWKLYEKNLKVVAENNLSDSFHSPMQGPLTTPSQLRLPRLNHHDMIIAAYPRRVYANAHAYHINSISVNSDAETYISADDLRINLWNLSISDHSFNIVDIKPENMEELTEVITSAEFHPINCNHLMYSSSKGNIKLLDLRQSALCDNPCKLFEDQEDQDSKSFFSEIISSISDVKFSQNGRYILSRDYLTLKIWDVNMEKAPVKTIPLHDVLRSKLCDLYENDCIFDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGQIVLQADKAAFRARKSAANNVPKLNAVKNNDWRSQPQAAMGSASVGLDPDNLDYNKKILHASWHPFEDSVAIAATNNLFVFSKL
What is the function of this protein?
Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase.  The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.
What are the official names of this protein?
Protein phosphatase PP2A regulatory subunit B, Protein phosphatase 2A 55 kDa regulatory subunit, PR55.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
Protein: CEA18_MOUSE
Sequence: MDFSRPSFSPWRWLTLVASLLTCGICQASGQIFISPDSLLGVEKYRTILTLENVPEDVLEYSWYRGKDNSTENMIFSYKPPNTRHPGPSYSGRENVTRAGSLVVRMSAVNDTGYYTVEVDTSNETQRATGWLQIVKLRSNPGISANTSALVEGMDSVVAKCLTNSSNISWYVNFVPTSGSNRMTISPDGKTLIIHRVSRYDHTLQCAIEDVPEILQKSELIQLTVAYGPDYVSLWTQPYFFAGVLTADIGSSVQLECNCFSKPEPRYHWIHNGSFLSIPENNMTLPSLSWEQMGSYRCVVENPETQLTFYRDVTIQPPRPPLPTVNRELYIPGPLVIFLILLTSLGGAFVCRVLVYSLFQSCSRGKTCHKCPWQTN
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 18.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SRP54_THEGJ
Sequence: MALEKLGKALNSALRKLARSSTVDEALIREVVRDIQRALIQSDVNVRLVLQLTKRIQERALNEKPPAGVSPREHVIKIVYEELTKLLGKEAVPLEIREKPTILLTVGIQGSGKTTTIAKLARHLQKRGYKVGLVCTDTWRPGAYYQLKQLVEPYNIEVFGDPGEKDAIKLAREGVEYFKDKGVDVIIVDTAGRHKEESGLIEEMKQISEAIKPHEVILVIDGTIGQQAYHQALAFKEATPIGSIIVTKLDGSAKGGGALSAVAATGAPIKFIGVGEKIDDLEPFDPKRFVSRLLGLGDIQGLLEKIEELQKEQEFKEEDVEKFLRGKFNLKDMYAQLEAMQKMGPLKQILQMIPGLGYSLPDEAVRVGEEKLRRYRIIMDSMTEEELENPDIINYSRIKRIARGSGTSTREVRELLAQYNQMRKMFKNLDKRKLAKMAKKFNFGGLGI
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: Y2626_ARATH
Sequence: MRGSNNTDLFDPKTEMDSNFSRHGSSSEGDFGFAFNDSNFSDRLLRIEILGGPSDSRSDAEGCTSIADWARHRKRRREDNKKDNGVAISDIVACAEEQILTDNNQPDMDDAPGGDNLDDEGEAMVEEALSGDDDASSEPNWGIDCSTVVRVKELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRISAQEEGALMELLNFMYSNSLSVTTAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPDSALLYLELPSSVLMAEAVQPLTDAAKQFLASRYKDITKFHDEVMALPLAGIEAILSSDDLQIASEDAVYDFVLKWARGQYSSLEDRREILGSRLALYIRFPYMTCRKLKKVLTCSDFEHEVASKQVLEALFFKAEAPHRQRILAAEGSDSMNRRFIERAYKYRPVKVVEFELPRPQCVVYLDLKREECAGLFPSGRVYSQAFHLGGQGFFLSAHCNMDQQSSFHCFGLFLGMQEKGAVSFGVDYEFAARDKSTKEEYVSKYKGNYTFTGGKAVGYRNLFGIPWTSFIAEDSQHFINGILHLRAELTIKRSSDLH
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At2g46260.
Protein: ILVC_CERSK
Sequence: MRVYYDRDCDINLIKDKKVAILGYGSQGHAHALNLRDSGAKNVVVALREGSPSAKKAEAEGLKVMGIAEAAAWCDLIMFTMPDELQAETYKKYVHDNLREGSAIAFAHGLNVHFGLIEPKPGVDVIMMAPKGPGHTVRGEYVKGGGVPCLVAVHNDATGKAMEIGLSYCSAIGGGRSGIIETNFRQECETDLFGEQAVLCGGLVELIRMGFETLVEAGYEPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRILPYEETKARMKAVLTDIQTGKFVRDFMQENAVGQPFFKATRRINDEHQIEQVGEKLRGMMPWISKGKMVDRARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CAS1B_XENLA
Sequence: MTAQLNKVRKAIINGCNPAMISDLLDDLQDKHVLKDYEVEHINKKNNTSRDRCRDMIDSVKKKGEYSSNILLESLVKNHKTLAESLGLHEHAPSPIQEHNEDTIKDKEINSVIPCSAEEFKNIYDSHGDKIYEVREREGRKRLALIICNETFQSMSERRGAKLDLEGMNKLLNELGYQVQQHTNLTKAEMVKAMKEFAAREEHADSDSTFIVLMSHGDKPGVCGTDSKKTENGQYGVTNLLQVDEIFSTFNNVNCSRLWDKPKVIIIQACRGENQGGELVRDDVAPAPLEDDAVHHVQTETDSICFYSSTPDTASWRNPTKGSVFIIRLIEKMNELAHCQPLGDIFLEVQSSFKDKSPNQYSQMPTQERSTMTKKFYLFPGY
What is the function of this protein?
Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides.  Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18, releasing the mature cytokines which are involved in a variety of inflammatory processes.  Cleaves a tetrapeptide after an Asp residue at position P1.  Also initiates pyroptosis, a programmed lytic cell death pathway, through cleavage of GSDMD.
What are the official names of this protein?
Caspase-1-B, CASP-1-B, Interleukin-1 beta convertase homolog B, xICE-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: PUR3_STAAW
Sequence: MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVSLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
What is the function of this protein?
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: LSPA_OLEA2
Sequence: MRPRFFVVYLIAALVIAVDQWTKQWAASTIPPLIGYTVIPGFFDLVNVRNRGAAFGFLNRSDIEWQFWLFFAAAVTAVLAIIAMTRSAKSNPYLFTGFGLIMGGAIGNLIDRIRFRAVIDFLDFHIGGYHWPAFNVADMGICVGAFFVCLAVYKHK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TCTP_CANGA
Sequence: MIIYKDIFSGDELLSDAYDINEVDGVIYEADCAMVKVGGDNIDIGANPSTEDGEDDVEDGTEVVNNVVHSFRLQPTGFDKKSFLTYIKGYMKAVKAKLQEKNPDAIPTFEKGAQVYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKHGIDEEKI
What is the function of this protein?
Involved in protein synthesis.  Involved in microtubule stabilization (By similarity).
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL30_LEUCK
Sequence: MADLKITLIKSAAHRLPKQRAIVKSLGLGRVSSSVVKPNNEATRGAIFHIAHLVSVEEVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RRF_PARL1
Sequence: MADTTFDIDDTERRMRGALQSLKQEFAGLRTGRATASLLEPIVVEAYGQSMPINQVGTIGVPEPRMLTVQVWDKGMISAVEKAIRSSGLGLNPNVDGMLIRLPIPELNQERRAELTKIAAKYTEQARIAVRNVRRDAMDELKRLEKDSHMSQDDHKSWSEKVQKLTDKVIGEIDAALAHKEADIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFAP5_MOUSE
Sequence: MLFLGQKALLLVLAISIPSDWLPLGVSGQRGDDVPETFTDDPNLVNDPSTDDTALADITPSTDDLAGDKNATAECRDEKFACTRLYSVHRPVRQCVHQSCFTSLRRMYIINNEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENMNLQRPDGL
What is the function of this protein?
May play a role in hematopoiesis.  In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (PubMed:23963447).  Component of the elastin-associated microfibrils (By similarity).
What are the official names of this protein?
Microfibrillar-associated protein 5, MFAP-5, Microfibril-associated glycoprotein 2, MAGP-2.
What is the protein family that this protein belongs to?
Belongs to the MFAP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DKTX_CYRSC
Sequence: DCAKEGEVCSWGKKCCDLDNFYCPMEFIPHCKKYKPYVPVTTNCAKEGEVCGWGSKCCHGLDCPLAFIPYCEKYRGRND
What is the function of this protein?
Selectively activates the heat-activated TRPV1 channel.  It binds to TRPV1 in an open state-dependent manner, trapping it there to produce irreversible currents (PubMed:20510930, PubMed:26880553, PubMed:27281200).  It binds to the outer edge of the external pore of TRPV1 in a counterclockwise configuration, using a limited protein-protein interface and inserting hydrophobic residues into the bilayer (PubMed:26880553, PubMed:27281200).  It also partitions naturally into membranes, with the two lobes exhibiting opposing energetics for membrane partitioning (K1) and channel activation (K2) (PubMed:26880553).  In addition, the toxin disrupts a cluster of hydrophobic residues behind the selectivity filter that are critical for channel activation (PubMed:26880553).
What are the official names of this protein?
Tau-theraphotoxin-Hs1a, Tau-TRTX-Hs1a, Double-knot toxin, DkTx.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 23 family. Double-knot toxin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HNS_ECO57
Sequence: MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ
What is the function of this protein?
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction.  Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome.  As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes.  A subset of genes are repressed by H-NS in association with other proteins (By similarity).
What are the official names of this protein?
DNA-binding protein H-NS, Histone-like protein HLP-II, Protein B1, Protein H1.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: UBL5_HUMAN
Sequence: MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ
What are the official names of this protein?
Ubiquitin-like protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y935_METJA
Sequence: MSIEKAKEDFKYLINRGYKKDVALNFVANHYKLSKEDRLKIIRTTHSDKEIKLTKRKLKKLKDFKGKTIYIDGFNVLISLEALIKGNKIVLCDDNIYRDFENVYGKYKINEYSDKAISLLLEILKHYNIKAVIYLDAQVSKSGILAKKIREKMKAFSIEGEVFCVKNCDYELKNKEVVATSDSVIIKSENVKYVVDLIAEAIEYLKKK
What are the official names of this protein?
Uncharacterized protein MJ0935.
Protein: TRPB_RHIEC
Sequence: MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKSDPAFQAELKHLGAHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGAEAKEQMLAAEGRLPDLVVAAVGGGSNAIGIFHPFLDDSSVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHSWLSDIGRVDYVPIMDHEALEAFQTLTRLEGIIPALEAAHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.  Essential for production of nod factors and establishment of symbiosis.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PXDN1_CAEBR
Sequence: MNLLLYLLLLVPWVLGSEDGCPAKCTCDKKGFTVDCSNAGLTRIPKGISSNVRSLVLRNNRIHTLIKSDLEGFPLLESLVLTHNKIKVVEENILDHLPELKRLSLSHNLLVYIPPLASESRPLASLNLKRNHIQFIDERWLLQYFPELVQIDLSHNRIQSLRTKLFENLPSLTHAHLHANPWNCDCRVTKVKALLRKVEWERKAYCTNPVELRHQAIDEVEESLLKCAKPEEESWTGDEFKLVCTKNASSSRPVVWLYENAEVDSSSLDGYEIHDSVITVPRKTNVNQMTCTYDYEHVPHHRRLRQSHHSNGAPQFTYKPRDNSYREGSEVKVNCEVMGTPKPSITWYHNGVRFASSRKKQLGLSNNVLRIYPFLEEDSGRYTCEAVNSLGKVSHTFSLDLISSIPPNIYEGPQSVSQNIGGEVVFVCKAKGNPTPDYTWSFDGSTIGHIKGRFMVSDDGTELXISNIEKKDEGYYSCMAGNPVGAMSADAKLTVIGGETRKSSTPQIDEELLRAIAQKARQNVESAVEKTRKQLNQDKITNTNDLKRLFRFSTPKQAVELSKAREIYEESVRLVREHVEKGLILNVDELHPNNVSYESVLHVTHVQALMGLSGCHTGQFKNPCTDTCFHNKYRSFDGQCNNKNKPMNGVSLMPLRRLLKPVYENGFNTPVGWEKGKLYNGYPMPNVREVSRQLVATETITPHRKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGAFCNRTCDNLDPCFNIPLSPSDPRVISESAKYPCIEFERSAAVCGSGETSLVFNRVTYREQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGQLRYDITSAAGKEYLPFEKDSNMDCRRNFSEENPIRCFLAGDLRANEQLALAATHTIFVREHNRIAKKLKKMNGNWDGEVIYHETRKIIGAMMQHITFKHWLPVVFGGQEQMDKFVGKYQGYDPAIDSSVTNAFATAAFRFGHTIINPTLFRLGNDFMSIKQGHIALHKAFFTPELVLTEGGIDPLLRGLFASPLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRQFCNLPVPARWEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKMRDGDRFWYEKDGVFTPEQMKEIKKVTLARLLCDNGDEIDRIQKDVFMYPGKEKENYGRCEDTEMMDLKAWSKCCDDVCPTMLDRILRSRHRGSRLHGCNQNGLWRPEGAKWIPPNEYCTEEAVFGAPPKKTVLTTEVHSSQRNSVLY
What is the function of this protein?
Catalyzes the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV NC1 hexamer (By similarity).  Plays a role in the attachment of tissues and in axonal guidance during early developmental stages (By similarity).  May functionally antagonize the peroxidasin pxn-2 to maintain neuronal development (By similarity).
What are the official names of this protein?
Peroxidasin homolog.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Localizes to the extracellular space in between body wall muscle cells.
Protein: Y4916_VIBPA
Sequence: MFDDLPPISHKEQQEAVERIQELMAKGTSTAEAIKIVADQIRAEYAAKQQGS
What are the official names of this protein?
UPF0181 protein VPA0916.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: MPTA2_METAR
Sequence: MILPDVQATKSEVAINLSRVGVTNVKKLVKVARPDKRPIILISTFNMYVDLPSERRGANLSRNFEVIDEVLEDMVKSPVYEIEDLCGEVARRLLNRHEYATRSEVHMDSELIVKRKTPQTEMQSQKVVKVFAKAIAERGEAIKVRRVIGSEVIGITACPCAQEIMRVSAENELQNLGVPQEKIDAFLNKIPMATHNQRGRGIVSIETAGEYEVPLNTLINIIEQSMSTMSFELLKRGDEYEVVRNAHANPKFVEDCVRDMARRVVTEFKDLPDDAVVKIKQINEESIHQHNAFAELSTTMGKLRTEIGQ
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA 2, GTP cyclohydrolase IV 2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: PP399_ARATH
Sequence: MKSDFLTSTTHFNPSIFLPKIPSRNSRISIKSSSSSSKVRPDPWSLSDGNPEKPKPRYERPKHPLSDDDARRIIKKKAQYLSTLRRNQGSQAMTPKWIKRTPEQMVQYLEDDRNGQMYGKHVVAAIKTVRGLSQRRQGSDDMRFVMSSFVAKLSFRDMCVVLKEQRGWRQVRDFFSWMKLQLSYRPSVVVYTIVLRLYGQVGKIKMAEETFLEMLEVGCEPDAVACGTMLCTYARWGRHSAMLTFYKAVQERRILLSTSVYNFMLSSLQKKSFHGKVIDLWLEMVEEGVPPNEFTYTLVVSSYAKQGFKEEALKAFGEMKSLGFVPEEVTYSSVISLSVKAGDWEKAIGLYEDMRSQGIVPSNYTCATMLSLYYKTENYPKALSLFADMERNKIPADEVIRGLIIRIYGKLGLFHDAQSMFEETERLNLLADEKTYLAMSQVHLNSGNVVKALDVIEMMKTRDIPLSRFAYIVMLQCYAKIQNVDCAEEAFRALSKTGLPDASSCNDMLNLYTRLNLGEKAKGFIKQIMVDQVHFDIELYKTAMRVYCKEGMVAEAQDLIVKMGREARVKDNRFVQTLAESMHIVNKHDKHEAVLNVSQLDVMALGLMLNLRLKEGNLNETKAILNLMFKTDLGSSAVNRVISSFVREGDVSKAEMIADIIIRLGLRMEEETIATLIAVYGRQHKLKEAKRLYLAAGESKTPGKSVIRSMIDAYVRCGWLEDAYGLFMESAEKGCDPGAVTISILVNALTNRGKHREAEHISRTCLEKNIELDTVGYNTLIKAMLEAGKLQCASEIYERMHTSGVPCSIQTYNTMISVYGRGLQLDKAIEIFSNARRSGLYLDEKIYTNMIMHYGKGGKMSEALSLFSEMQKKGIKPGTPSYNMMVKICATSRLHHEVDELLQAMERNGRCTDLSTYLTLIQVYAESSQFAEAEKTITLVKEKGIPLSHSHFSSLLSALVKAGMMEEAERTYCKMSEAGISPDSACKRTILKGYMTCGDAEKGILFYEKMIRSSVEDDRFVSSVVEDLYKAVGKEQDV
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g27270, Protein EMBRYO DEFECTIVE 976.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: TTRB_SALTY
Sequence: MWTGVNMDSSKRQFLQQLGVLTAGASLVPLAEAKFPFSPERHEGSPRHRYAMLIDLRRCIGCQSCTVSCTIENQTPQGAFRTTVNQYQVQREGSQEVTNVLLPRLCNHCDNPPCVPVCPVQATFQREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQTADKCTFCVHRLEAGLLPACVESCVGGARIIGDIKDPHSRIATMLHQHRDAIKVLKPENGTSPHVFYLGLDDAFVTPLMGRAQPALWQEV
What is the function of this protein?
Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate.  TtrB is probably involved in transfer of electrons from TtrC to TtrA.  During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S. typhimurium over the competing microbiota in the lumen of the inflamed gut.
What are the official names of this protein?
Tetrathionate reductase subunit B, Tetrathionate reductase electron transport protein.
What are the subcellular locations of this protein?
Periplasm. Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Protein: RK2_AETCO
Sequence: MAIHLYKTSTPSTRNGAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNAKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATIKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGYPALGRRTRKRKKYSETLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LMP1_EBVR
Sequence: MDLDLERGPPGPRRPPRGPPLSSSIGLALLLLLLALLFWLYIIMSNWTGGALLVLYAFALMLVIIILIIFIFRRDLLCPLGALCLLLLMITLLLIALWNLHGQALYLGIVLFIFGCLLVLGLWIYLLEILWRLGATIWQLLAFFLAFFLDIILLIIALYLQQNWWTLLVDLLWLLLFLAILIWMYYHGQRHSDEHHHDDSLPHPQQATDDSSNQSDSNSNEGRHLLLVSGAGDGPPLCSQNLGAPGGGPNNGPQDPDNTDDNGPQDPDNTDDNGPHDPLPQDPDNTDDNGPQDPDNTDDNGPHDPLPHNPSDSAGNDGGPPQLTEEVENKGGDQGPPLMTDGGGGHSHDSGHDGIDPHLPTLLLGTSGSGGDDDDPHGPVQLSYYD
What is the function of this protein?
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation (PubMed:16009714).  Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family.  LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells.  Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.  For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses.  Inhibits also host IFN-alpha-stimulated STAT2 nuclear translocation and interferon-stimulated response element transcriptional activity by interacting with and inhibiting host TYK2.  Induces SUMO expression during viral latency thereby dysregulating the host sumoylation processes (By similarity).
What are the official names of this protein?
Latent membrane protein 1, LMP-1, Protein p63.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae LMP-1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: FTHS_DESDA
Sequence: MTLDPTKHPDWKIALDAESRMKTVETLAAELGLEKAELLPYGHYMGKVEQQAVMQRLKDRPNGKYIDVTAITPTPLGEGKSTTTIGLVQGLARRGRRSSAAIRQPSGGPTMGMKGSAAGGGLSQCIPLTPYSLNFTGDLHAVGAAHNLGMTALTSRMQHERNYDDATLEKLSGMARLNIDPTRINTGWVMDFCVQALRNIIIGIEGDGRRNDGFMMRSHFDITVASEVMCILSIARDLRDLRERMGRMVLAHDRNGKPVTTSDLGVAGAMTAWLVEAAKPNLIQTIEGQPVFVHTGPFANIALGQSSVIADRVALKLSDYHVTESGFAAEMGYEKFWNLKCHYSGLVPDAAVVVATVRALKNHGGAPQPKPGQALPEPYTREDVGLVEAGCANLLHHLGIVRRSGVPAVVCINKFHTDTKAEVDAIRRICEQAGARVALSEHWEKGGEGALELADAVTDACNEKNEFRPLYNWNSPLTERITTIAQEVYGADGVEFEPLAAQRLKDLQERPDADELGVCMVKTQYSLSDKPALKGVPKGWRLHVRDVLFFGGAGLVAPVSGDISLMPGTGSKPAFRNIDVDVETGKVTGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.