PharMolix/UniProtQA huggingface dataset:
Protein: SF3B3_MOUSE
Sequence: MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFGVIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTGEDWYVLVGVAKDLILSPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRGLLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTPPEVSKKLEDIRTRYAF
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome.  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.  May also be involved in the assembly of the 'E' complex.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, SF3b130, Spliceosome-associated protein 130, SAP 130.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MAP1_STAAN
Sequence: MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: MBD8_ARATH
Sequence: MDDGDLGNNHHNFLGGAGNRLSAESLPLIDTRLLSQSELRALSQCSSLSPSSSASLAASAGGDDDLTPKIDRSVFNESAGSRKQTFLRLRLARHPQPPEEPPSPQRQRDDSSREEQTQVASLLRSLFNVDSNQSKEEEDEGEEELEDNEGQIHYNSYVYQRPNLDSIQNVLIQGTSGNKIKRKRGRPRKIRNPSEENEVLDLTGEASTYVFVDKTSSNLGMVSRVGSSGISLDSNSVKRKRGRPPKNKEEIMNLEKRDSAIVNISAFDKEELVVNLENREGTIVDLSALASVSEDPYEEELRRITVGLKTKEEILGFLEQLNGEWVNIGKKKKVVNACDYGGYLPRGWRLMLYIKRKGSNLLLACRRYISPDGQQFETCKEVSTYLRSLLESPSKNQHYYLQSDNKTLGQQPVIANESLLGNSDSMDSETMQYLESGRTSSEVFEEAKAVENGNEADRVKTSLMQKDDNADFLNGVEDNDDDMKKRDGNMENLATLSNSEMTKSLPTTTNELQQYFSSQINRVQ
What is the function of this protein?
Probable transcriptional regulator (By similarity).  May regulates developmental traits such as flowering time.
What are the official names of this protein?
Methyl-CpG-binding domain-containing protein 8, AtMBD8, MBD08, Methyl-CpG-binding protein MBD8.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTR1B_MOUSE
Sequence: MPENSSIPNCCEASGLAARPSWSGSAGARPPVTARAPWVAPMLSTVVVVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVSLALADLVIALYPYPLILVAIIRDGWVLGEAHCKASAFVMGLSVIGSVFNITAIAINRYCCICHSTTYHRVCSHWYTPIYISLVWLLTLVALVPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVAIHFLLPMAVVSFCYLRIWVLVLQARRKAKATRKLRLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQVPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILLAIWNTRRCIQHASKHCLTEERQGPTPPAARATVPVKEGAL
What is the function of this protein?
High affinity receptor for melatonin.  The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity).
What are the official names of this protein?
Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_LACJO
Sequence: MKQLTSSQVRQMFLDFFKEHGHMVMQSASLIPQDDPTLLWINSGVATMKKYFDGSVVPKNHRITSSQKSIRTNDIENVGKTARHQTFFEMLGNFSVGDYFKKEVIPWAWEFLTSPKWLGLDPDKLYVTVYPKDTEAYHMWHDVVGLPEDHIVKLEDNFWDIGEGPCGPDSEIFYDRGQENNDVAEDDPENFPGGENARYLEIWNIVFSQFNHLPNGKYVDQPHKNIDTGMGLERVVSIIQDAPTNFETDLFMPIIKETEKLSDGKKYAANKEDDVAFKIIADHVRAVSFAIADGALPSNSGRGYVLRRLIRRADLNGQRLGIKGAFLYKLVPVVGEIMKSHYPEVVDQQAFIQKVIKNEEERFQVTLSSGLNLLDNIIAEAKKSDDKTISGKDAFKLFDTYGFPYELTFEAAQDAGLKIDKKGFDEEMKAQKERARKARGNLQSMGSQDVTLMNIKDKSEFEYGTLEEKHAKLIDIVVDDKLVDKADGEHATLIFDKTPFYAERGGQVADHGEILNQNGELVARVTDVQHAPNDQNLHFVDVILPLEKGQEYVLKVDQKRRRGLKHNHTATHLLHAALREVLGTHTHQAGSLVEPDYLRFDFTSLEPMTKKEIASVEKLVNEKIWEEIPVKTTVTDPDTGLKMGALALFGEKYGDTVRVVQIDDFSTEFCGGTHCENTDQIGMLKIVSESAVGAGTRRIIAVTGPEAYKYVTDRDEILKEVQDEVKATKAEDVVNKISSIEDDLRASQKEAEQLKAQINKAKAGDLFNDIKQVKDLTVIAAQADVEGMNDLRELADNWKSSNKSDVLVLAAEVNGKANMVISLDDKAIKAGLKAGDLIKTAAPIFGGGGGGRPNMAQAGGKNPAGLKDAIAKVLQEVEEKQN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1241_CLOAB
Sequence: MINNSLKITDLPNNERPRERLLRYGSEVLSNSELLAIILRTGTLHENIINLSSRILKESGGLNGVLNLSFEELKKVKGIGNAKAVQILALGELFKRFKAYKSFESVKITSPKEAANLVMEQLRSFNKEHLYVIMLNTKNIVIKISDVSVGSLNSSIVHPREVYVEPILKHAASIILCHNHPSGDPKPSNEDLNITKRLYECSKFIGIELLDHIIIGDGIYISLKEEGLL
What are the official names of this protein?
UPF0758 protein CA_C1241.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: ISCR_PHOLL
Sequence: MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASEIVVAEVIFAVDESVDATRCQGREGCQGGDRCLTHALWRDLSDRITGFLSSISLEELVNNQEVLDVAGRQDNDKRRAPNGRAQETINVNLRP
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: RL4_FRATN
Sequence: MDLNIKSLAGQEAGSLGVAEGVFAADYNEALIHQVVVAYMAGARQGTKAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIFRKGGVTFAAKPKSYKQKVNRKMYSGAVKSILSELLRSGRMTIVEELKLETPKTREFKSVIDSLGVKDVLFVVGVEEFSENLYLSSRNLKNVAVCDSVEINPVSLVCFENVVLTKKAIKEIEEKLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y2204_VIBPA
Sequence: MSKKDTEHDDDFALFKEAVQGVKKLRQDTIIQQPKKNTKQKEIKRSNREASDSEFYFSDEFVPRLNEEGPTRYARDDVSTYEVKRLRRGVYVPDVFLDMHGMTQQEAKRELGAMIAYCVKNEIHCACVQHGIGKHILKQKAPLWLAQHPDVMAFHQAPLEFGGDGALLVLLSIPEK
What are the official names of this protein?
UPF0115 protein VP2204.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: ACCD_STRPZ
Sequence: MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHMIYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKLQKAKEITGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEENLPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIETTVRENLPDNFQKAEFLQDHGFVDAIVKRTELRDKIAHLVSFHGGGQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_STRS7
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERALPFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GLYM_ASHGO
Sequence: MFIRRLHTSSRRLTCGEALRACQQTGARSANGQLMLSQHVQEFDPEMYDILTKERSRQKRSITLIPSENFTSVAVMNLLGSEMQNKYSEGYPGQRYYGGNQYIDMAESLCQKRALELYGLDPAKWGVNVQSLSGAPANLYAYSAIMEVGDRMMGLDLPHGGHLSHGYQLQNGNKISYISKYFQTMAYRVDPATGLVDYDTLSETSKLFRPKVIVAGTSAYARVLDYKRFREIADACGAYLLSDMAHVSGLVAAGVHPSPFEYSDIVTTTTHKSLRGPRGAMIFYRKGIRKVTKKGTEIMYDLDKRINFSVFPAHQGGPHNHTISALAVALKQAATPEFKNYQTAVVENAKVFGEELSKRGFSLVSGGTDTHLLLIDLSPMGIDGSRLETILERLNIAANKNTIPGDKSALYPSGLRVGTPAMTTRGFGPAEFGRVAAYINEAVKLAIGLKSQEPVDAKDAKTRLAHFKSFCAESEQVTKLANEVADWVAQYPVPGEL
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, mitochondrial, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SP5G2_LISMO
Sequence: MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG 2.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: RNAS6_CHLAE
Sequence: MVLCFPLLLLLLVLWGPVCLLHAWPKHLTRAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIICKNRQHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAGLYKFFIVACDPPQKSDPPYKLVPVHLDSIL
What is the function of this protein?
Ribonuclease which shows a preference for the pyrimidines uridine and cytosine.  Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P. aeruginosa, A. baumanii, M. luteus, S. aureus, E. faecalis, E. faecium, S. saprophyticus and E. coli.  Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria.  Probably contributes to urinary tract sterility.  Bactericidal activity is independent of RNase activity.
What are the official names of this protein?
Ribonuclease K6, RNase K6.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Cytoplasmic granule.
Protein: NRDR_THEMA
Sequence: MKCPFCGSMDTRVLDSRPTLDGTAIRRRRECSSCGKRFTTYERYEEAPVLVVKKDGRREKFDREKIKNGMIKACEKRPVTYEQIEEAVNRICLKLREEGSFEVETKRIGELVMEELKKLDQVAYVRLASVYRDFREVDQFLEIVKELKREKEGEEQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CCA_SHEB8
Sequence: MKIYLVGGAVRDSLLNLPIKDKDYLVVGATPEQMLQLGYRQVGKDFPVFLHPKNQQEYALARTERKIGLGYGGFSCHASPDVTLEQDLLRRDLTINAIAQDEKGNLYDPFNGIEDINARLLRHVSDAFVEDPLRVLRVARFAARFHALGFHIAAETLALMRQISASDELNALTAERVWQEVDKSLGGPHPEVFFEVLHQCGALEVLFPEIFALFGVPQPEKWHPEIDTGVHTLMVLAQAALLTEDKSVRFAALVHDLGKALSPKEHLPKHHGHGQKGLPLIKALCTRLRVPNETRDLALLVSDQHQNVHQAFELRAETIVKIFDKADFWRKPERLTQLILACTADMRGRTGFENNLYPQGEYLTQCFLAANNVDIAAIIAAGFQGAEIKQALNLRRIEAVSQFKQKMQTKLPTDER
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RECF_NOSS1
Sequence: MYLKTLHLRHFRNYYDQKVEFTAAKTILVGNNAQGKSNLLEAVELLATLRSHRMARDRDFVQEEEPVAQINATLERDTGVSDLSLILRRNGRRTVALNGEPLRRQMDFLGVLNAVQFSSLDLELVRGSPEVRRNWLDTLLIQLEPVYAHILQQYNQVLRQRNAYLKKLQDSALTTQDSALAIWDAQLVTTGTKVIRRRDRALARLAPLATAWHTSISGSTEVLQINYTPNVQLVKNQPEEVQQAFLSQLQQRAVPEIYRGTTLVGPHRDEVELTINQTPARQYGSQGQQRTLVLALKLAELQLIEEVVKEPPLLLLDDVLAELDPSRQNQLLDTIQDRFQTLITTTHLSSFDAQWLNSSQILFVEQGKISTSNAVR
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD11_ORYSJ
Sequence: MMYKHVGDDARGSSAGVVCCVDVVDDDVDALLCGEDAGELEREGEPAQGSSPSSSLSCAAAAAAAADDDDEDEDEHGVHGEVVQVTPGGEEHCYDYDYDVDVPVGAELVMPACSPPRTAVHRPGWSESVSWILKVRSVHGFQPATAYLAVSYMDRFMSSRSLPDHGWASQLLCVACLSLAAKMEESSAPPLLDLQIEGTRFIFEPRTIQRMELIVLVELDWRLRSVTPFAFVDFFACKVGSSGRSSRILALRACQIILSAIHELEFLNHCASSMAAAAVLFAVNESPAAMSHRSSVSSESAASWCIGLTEERISSCYQLLQRALNATARKRKRHPMILAACSSVTSSSSRSKRRKLDGHFGED
What are the official names of this protein?
Cyclin-D1-1, G1/S-specific cyclin-D1-1, CycD1;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: DEOC_STRPG
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEATKPDSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DROPS
Sequence: MTIRPAYRPKIIKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHAVSSKKRKEIVERAKQLSIRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: RS10_STRA5
Sequence: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RNH2A_HUMAN
Sequence: MDLSELERDNTGRCRLSSPVPAVCRKEPCVLGVDEAGRGPVLGPMVYAICYCPLPRLADLEALKVADSKTLLESERERLFAKMEDTDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTATGLIQYALDQGVNVTQVFVDTVGMPETYQARLQQSFPGIEVTVKAKADALYPVVSAASICAKVARDQAVKKWQFVEKLQDLDTDYGSGYPNDPKTKAWLKEHVEPVFGFPQFVRFSWRTAQTILEKEAEDVIWEDSASENQEGLRKITSYFLNEGSQARPRSSHRYFLERGLESATSL
What is the function of this protein?
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
What are the official names of this protein?
Ribonuclease H2 subunit A, RNase H2 subunit A, Aicardi-Goutieres syndrome 4 protein, AGS4, RNase H(35), Ribonuclease HI large subunit, RNase HI large subunit, Ribonuclease HI subunit A.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. Eukaryotic subfamily.
Protein: CSRA_SHISS
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: RPOB_ZYMMO
Sequence: MGRLVVKREDYMATKASAIGHASVKKRIRKMFGNIHEVVDMPNLIEVQRDSYENFLRSRPEDGYVSGLEKTLRSVFPIRDFGGVAELDFVQYELEEPKFDVDECRQRGITYAAPMRVTLRLIVFEVDPDTETRSVLDIKEQDVYMGDMPLMTRNGTFFINGTERVIVSQMHRSPGVLFDHDKGKTHSSGKFLFAARVIPYRGSWLDFEFDAKDIVNVRIDRKRKLPVTTLLYALGLNAEQILHHFYNTITFVRGDGGWKVPYVAESWRGRKPFFDIINGDTGEVVFPAGQKISPRAANKAGRDGLETLLIPTEEIYGHYAAYDVIDESTGRIWIEAGDEVTPENLELLDNAGVATLELLDIDHVSTGPWIRNTLKADKAEDRDHALAEIYRVMRPGEPPTKETAEALFYGLFFDPERYDLSAVGRVKLNMRLDLDCPDTVTTLRAEDILAVVKTLVDLKDGKGEVDDIDNLGNRRVRSVGELLENQYRVGLLRMERAVKERMSSVDVSTVMPNDLINAKPAVAAVREFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFSRINKYGFIETPYRKVVDHKVTNEVIYLSAMEESRYTVAQANAELDAEGHFVEELVSAREAGEFLMAPREQITLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVSLVRAEAPFVGTGMEETVARDSGAAISARRAGIVDQVDASRIVIRTTGEIEAGKPGVDIYRLMKFQRSNQSTCINQRPLVSVGDYVNAGDVLADGPSTELGELALGRNVLVAFMPWNGYNYEDSILISERIVKDDVFTSIHIDEFEVMARDTKLGPEDITRDIPNVGEDALRNLDEAGIVYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVAGTIVDVRVFNRHGVDKDERAMAIEREEIERLTKDREDERAILNRATYAQLQEKLLGQTVAAAPYKHIVKGARIDIETLASVEPHKWFKFAVEDDARQAELEAIKNQYDSADEAIRKRFEDRVEKAQRGDELPPGVLKMVKVFVAVKRKLQPGDKMAGRHGNKGVISRILPAEDMPFLADGTPVDIVLNPLGVPSRMNIGQIFETHLGWAARGLGAKVRTALEEWREANADRYEWDFSPPEVVRERMIEVYGEKYAEDIKSREDREIVEMAGLLRNGVPMATPVFDGAKPEDISEMLNLAGLDDSGQVELYDGRTGEQFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLQEMLTVKSDDVVGRTKVYEAIVKGDDTFEAGIPESFNVLVKEMHSLGLNVELKTSKAKDEDDSSFQVAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNMC_SACD2
Sequence: MTKKLEHEYIAHTERPALTWDEQGQPYSTEYDDVYYSTTDALAETRFVFLDKNNLAARWPHLTHQQTFTVCETGFGAGLNFLATWQLWRSTRPSGRMHFISFEKHPLNSAQIAKALNRWPQFAALSEQLCALYPPSSAPGFHHITLDEGQVQLTLYFGDAKTGLEQLVLAHGAINKIENRSSCIGDKQQLVDAWYFDGFTPAKNPSIWQPCIFTLAAELSKSTTTFATFTSARSVRDAIENAGFKWQKVPGFGLKREMLFGTFEQHPFAQVDPNKAPTTAHRSYRKRNGVQHSWHLQTANSEHQPPKTAIVIGGGLAGAHAAHALALRGVNVTLLERAPNLANGASSNLQGLVYTRLSLSGNPLSRFNMAAQLYADRFYHSHNFYTTCGEASGVLHLATSNAIEKQLRNIGEQHASTDPNPIFNWVEQQDTEQAVGVSTSTGGLFIRNSGWLNPVQLCHALTNHPRITKLFNSDAAQLQQDAHGQWFALTNDGHKLASADITVICTARDAKHLAQTAYLPMRNIRGQVSHLSSHGLSQRLHASVCGAGYIAPAQSGIHCAGASFNLHENTLDLREEDHQFNIDNLASMSKSLTFNPPLTTLDGKVGFRATTPDYFPIVGPVPIRDEFCERFAGYRKRAATPIPQTGPYYRGLYVSVGYGSRGLAYTPLATESLCHSIFGELQPIATETLLHLHPARFLFRDLTRNRI
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAD_ECO24
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: PKNE_MYCTU
Sequence: MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMVVNYQDPSWLARLIG
What is the function of this protein?
Important for survival of the bacterium in the host during infection.  Promotes the survival of infected macrophages by activating multiple signaling responses and suppressing apoptosis of macrophages during nitrate stress.  May contribute to the adaptation of M. tuberculosis during stress conditions by maintaining the cellular integrity.  Can phosphorylate the FHA domain of Rv1747.
What are the official names of this protein?
Serine/threonine-protein kinase PknE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.