PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_SALNS
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYRNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGINVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYP_THEAB
Sequence: MRFSRLYAPTLREDPSDAEIPSQALLQRAGFIRKIAAGVYTYLPLARRTLLKIENIVREEMDKIGAQEILMPIIQPAELWQRSGRWDDYGPEMMKLKDRHNRDFTLGPTHEELVTELIRNELNSYKQLPVSLYQITTKFRDEIRPRFGVLRAREFIMKDAYSFHDSWESLDETYQLFKDAYSKIMERIGLRYSVIEAATGAIGGNESHEFVAFANTGESNVLYCDCGYAGSDERVPYKGDYEKDDEAEKTLEKVYTPNVRTVEQVAEFLNVPIRKIVKSLVFKGRDGFVMALVPGDRELNFEKLKAYLGDQSLQMAEAEEILEEFGVPIGFLGPVGADKVRIVADYGIKYMKNFVVGGMEKDYHYLNVNLDRDFKVNEWTDLVVVQIGDPCPVCGKPLKGEKGIELGHIFKLGTKYSDSMDVKYMDKDGKMKSFIMGCYGWGISRTLGAIVEQLHDDDGIIWPRSVAPYEVDIVVVGKEKEKEFSEKLYSYLLDKGVDVIIDDRNVSPGVKFKDADLIGFPIRITVGRKLKEGKVEIKERGKEAILVDANMEQILNAINEM
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIA1_ARATH
Sequence: MDLMEKNLELVEIQKLEGHTDRVWSVAWNPVSSHADGVSPILASCSGDNTVRIWEQSSLSRSWTCKTVLEETHTRTVRSCAWSPSGQLLATASFDGTTGIWKNYGSEFECISTLEGHENEVKSVSWNASGSCLATCSRDKSVWIWEVLEGNEYDCAAVLTGHTQDVKMVQWHPTMDVLFSCSYDNTIKVWWSEDDDGEYQCVQTLGESNNGHSSTVWSISFNAAGDKMVTCSDDLTLKIWGTDIAKMQSGEEYAPWIHLCTLSGYHDRTIYSAHWSRDDIIASGAGDNAIRLFVDSKHDSVDGPSYNLLLKKNKAHENDVNSVQWSPGEGNRLLASASDDGMVKIWQLATKP
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Protein CIA1, Cytosolic iron-sulfur protein assembly 1, Protein EMBRYO DEFECTIVE 1345.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SECB_YERPP
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_THEP3
Sequence: MSIILKIKKTDDAKDLPLPAYMSEGAAGMDLYANVKEEVILQPGEIKLIPTGIQIELPPNFEAQIRPRSGLALNYGITLLNTPGTIDSDYRGEIKLIVINLGKEAVKIARGQRIAQMVINQIVRPTIVEAEILSETKRDEGGFGHTGI
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RISB1_RHILO
Sequence: MAGISQHGKAFIRPKAKAHLLIVEARFHDDLADALLDGATSALEEAGATYDVVTVPGSLEIPAVITFALDGAAEGGTNYDGFVALGTIIRGDTYHFDIVANESSRALMDMSVQDSVCIGNGILTTENDAQAWTRAKRSEGDKGGFAARAALTMIALKEQLGARS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 1, DMRL synthase 1, LS 1, Lumazine synthase 1, Type I lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KCY_RHILO
Sequence: MTHVFTIAIDGPAGAGKGTLARRLADHYRLNLLDTGLTYRAVAYALIQHALPLDNVSAAETAARQVDMAKLDRAVLSAHAIGEAASKVAVYPTVRRILVEKQRAFARTPPGAVLDGRDIGTVVCPDADIKLYVTASAEVRAMRRLAEIESIGGTANFTEILADIVRRDERDMGRADSPLKPAADAHLLDTSEMAIEAAFLAAMAIVDDVLTRRNKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_CLOBH
Sequence: MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEGRANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVREEGEWACIVSKIN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDLI1_RAT
Sequence: MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPGTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVGDQIYCEKHARERVTPPEGYDVVTVFPK
What is the function of this protein?
Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity).  Involved in assembly, disassembly and directioning of stress fibers in fibroblasts.  Required for the localization of ACTN1 and PALLD to stress fibers.  Required for cell migration and in maintaining cell polarity of fibroblasts (PubMed:22659164).
What are the official names of this protein?
PDZ and LIM domain protein 1, C-terminal LIM domain protein 1, Elfin, LIM domain protein CLP-36.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Associates with actin stress fibers.
Protein: GLGB_RHOPB
Sequence: MIANLPEEAYAIVEGRHADPFRYLGPHQENDRTVVRAFLPEASMVDAVDEHGGTATLERVHDAGLFVGLLPNGSGRYQLRARFGETTVDLDDPYRFPPILTDFDLYLLGEGTHQRLYDKLGAHPLTLDGVDGIAFVVLAPNAQRVSVVGDFNFWNPRRHPMRVRGSGYWELFVPRALAGDHYKFDIIGPHGQQLPLKSDPLAFAAEMRPDTASVVVDPARLSHPRPAPPAINALTSPMSIYEVHLGSWRRKDDNQWLSYRELAEVLPAYVRDLGFTHVEFLPVNEHPFDGSWGYQPTGLFAPTSRFGTPEDFIALIDACHRENIGVLLDWVPGHFPDDPHGLANFDGTALYEHANPLQGRHMDWGTLIYNYGRTEVVNFLVSNALFWLERYAVDGLRVDAVASMLYLDYSRPAGGWIPNKFGGRENLEAIDFLRRFNTEVYAKFPHATTAAEESTAWPQVSRPVEYGGLGFGYKWNMGWMHDTLDYISKDPIYRKHHHGEILFGLQYAFSENFILPLSHDEVVHGKRSLIGRMPGDAWQRFANLRAYYSFMFAHPGKKLMFMGCEFAQEREWNHDRSLDWHLLEQPEHQGIQALIRDLNGLYRRLPALHQLDCDGYGFEWIVTDDADRNVFAWIRKGNDARARCLVVANFSPSVYHDYRVRVPFPGKWREVLNSDSAHYGGSNVGNIGEVQTLDQLVPELSLSLPPLGVIFLTPED
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PYRF_BACC7
Sequence: MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGDEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RT05_SCHPO
Sequence: MLRSFSHFLQIGSRRQPTYFRCFHKTTVHLNSFKNDPKKELNSNLNEKSVEESSKNETKEQFNSSSIPRESESEGKTASNTSPLSPKKVENLSKLFNDINEDVSIEELKSRFKDHLPFYENYIRNHPLAIEALQKSTAPRQTGLKLNYVSKLDKYVTPLDGYSHLGSEESNGEIPDKWEDFKDDLTFEISSKFSPFDFGDAGKSTSDAEFLSDISGIPKSDLRALMFVPLVRRRVVNQTRKGKIASMYVLTVVGNRNGVAGFGEGKAESYSLAYKQSCGRAVKNMVYIPRYDKRTVYGVIHKKFHAVRLTLRSRPAGFGLRCNPILHEICRCAGIKDISGEILGSKNGMNTVKAMFEALQSQRLPEDIAMERGQKFVDVQREYYKQT
What are the official names of this protein?
Probable 37S ribosomal protein S5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPIKE_IBVD3
Sequence: MLEKSLLLVTLLFALCSANLFGNNSYVYYYQSAFRPPNGWHLHGGAYEVVNVSTESSNAGTTECTAGAIYWSKNFSAASVAMTAPQNGMLWSTAQFCTAHCNFTDFVVFVTHCYKSASGSCPLTGLIPQYHIRISAMKNSSLFYNLTVAVTKYPRFKSLQCVNNMTSVYLNGDLVFTSNETKDVSAAGVHFKAGGPITYKVMREVKALAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPFTNSSLVKEKFIVYRESSVNTTLELTNFTFSNVSNANPNTGGVHTIQLYQTSTAQSGHYNFNFSFLSSFTYKESDYMYGSYHPSCKFRLETINNGLWFNSLSVSLGYGPIQGGCKQSVFQNRATCCYAYSYNGPPLCKGVYRGELTKSFECGLLVFVTKTDGSRIQTRNEPFTLTQHNYNNITLDRCVEYNIYGRVGQGFITNVTNYAINYNYLADGGMAILDTSGAIDIFVVQGEYGLNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQPLENQFYIKIINGTRRSRRSITGNVTNCPYV
What is the function of this protein?
S2 is a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes (By similarity).
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses spike protein family.
What are the subcellular locations of this protein?
[Spike protein S2]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers may be transported to the plasma membrane, where they may mediate cell-cell fusion (By similarity). SUBCELLULAR LOCATION: [Spike protein S1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers may be transported to the plasma membrane, where they may mediate cell-cell fusion. S1 is not anchored to the viral envelope, but associates with the extravirion surface through its binding to S2 (By similarity).
Protein: NDK_BACAN
Sequence: MEKTFLMVKPDGVQRAFIGEIVARFEKKGFQLVGAKLMQVTPEIAGQHYAEHTEKPFFGELVDFITSGPVFAMVWQGEGVVDTARNMMGKTRPHEAAPGTIRGDFGVTVAKNIIHGSDSLESAEREIGIFFKEEELVDYSKLMNEWIY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROG1_PETHY
Sequence: MALSTNSTTSSLLPKTPLVQQPLLKNASLPTTTKAIRFIQPISAIHSSDSSKNTPIVSAKPSSPPAATSTAAATAVTKQEWSIDSWKTKKALQLPEYPNQEELKNVLKTIEDFPPIVFAGEARHLEEKLGEAAMGRAFLLQGGDCAESFKEFNANNIRDTFRILLQMGAVLMFGGQMPVIKVGRMAGQFAKPRSDNFEEKNGVKLPSYRGDNVNGDAFDLKSRTPDPQRLIRAYCQSAATLNLLRAFATGGYAAMQRVTQWNLDFTEHSEQGDRYRELANRVDEALGFMNAAGLTTDHPIMTTTEFWTSHECLLLPYEQSLTRLDSTSGLYYDCSAHFLWVGERTRQLDGAHVEFLRGIANPLGIKVSDKMDPSALVKLIEILNPQNKAGRITIITRMGAENMRVKLPHLIRAVRGAGQIVTWVSDPMHGNTIKAPCGLKTRPFDSIRAEVRAFFDVHEQEGSHPGGVHLEMTGQNVTECIGGSRTVTFDDLSSRYHTHCDPRLNASQSLELAFIIAERLRKRRLGSQSVLGQ
What is the function of this protein?
Involved in the production of volatile organic compounds (VOCs), including floral volatile benzenoids and phenylpropanoids (FVBP), in flowers of fragrant cultivars (e. g.  cv.  Mitchell and cv.  V26), scent attracting pollinators (e. g.  the night-active hawkmoth pollinator Manduca sexta) (PubMed:24815009).  Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate (By similarity).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1, DAHP synthase 1, PhDAHP1, Phospho-2-keto-3-deoxyheptonate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II DAHP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ALR_NOSS1
Sequence: MASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMAVVKADAYGHGAVTVAQTALQAGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQAIAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDTGMSRLGTNWQQAGEFVQLVERLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLADPRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAPHEMRLAVVSIGYADGVPRNLSNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIVTLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGVM
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: NS1_I54A0
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIKTATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RSMH_COXBR
Sequence: MEAHKPVLFDEVMEGLAIRPDGIYVDGTFGRGGHSFGILQRLGPNGRLMAMDKDPDAVAVANKALFEDARFSIVHETFANLQKAVRDRGWEGKVNGILLDIGVSSPQLEDAKRGFSFSKDGPLDMRMNPKQSMDAASWINQAAMEDIRRVLWNYGEERFAKRIAQAIVNAREEKPITRTQELSDIVIKAYPQREIKKHPATRTFQAIRIFINRELDELRECLPQCLETLAVGGRLCVISFHSLEDRLVKRFIQKESRDHLPREIPILAKDIKHRLKPLGSLIRPTEAEIKKNPRARSARLRIVEKLS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STRPN
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PROA_ECOUT
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIL_SALTY
Sequence: MACGEFSLIARYFDRVRSSRLDVETGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPEVDEPWLEAFSDSLFALLNYYDMQLIGGDTTRGPLSMTLGIHGYIPAGRALKRSGAKPGDWIYVTGTPGDSAAGLAVLQNRLQVSEETDAHYLIQRHLRPTPRILHGQALRDIASAAIDLSDGLISDLGHIVKASGCGARVDVDALPKSDAMMRHVDDGQALRWALSGGEDYELCFTVPELNRGALDVAIGQLGVPFTCIGQMSADIEGLNFVRDGMPVTFDWKGYDHFATP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: MTNA_METSB
Sequence: MRVEGKPYTTIWTGEDGASIKIIDQTRLPHRFEIIAISDVEAAARAIAEMWVRGAPLIGVTAAYGLALAMRADPSDANLERASAHLKATRPTAVNLQWAVDRVRRLIESAPPPQRFAAAFAEAGVIARDDIALCEAIGMHGLSLIKTIAAGKPPGAPVNVLTHCNAGWLATVDWGTATAPVYKAHDAGLAVHVYVDETRPRNQGAALTAFELGQHGVPHTVIVDNAGGHLMQHGGIDMVIVGTDRTTASGDVCNKIGTYLKALAARDNNIPFYVAAPSPSIDFSIADGVREVPIEIRSEAEVTHISGLSADGEITRVRLTPEGSRALNPAFDVTPARLVTGLITERGVIKANASALAAAFRERVAG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PURP_CENSY
Sequence: MKSVSTLGSHCSLQLLKGAKDEGFRTLLVCERRRERFYRRFGFIDELVLVDGFGELLGDECQSVLAENDSILIPHGTLVAQMSPDQIESIGVPVFGNKWILRWESDRSLKERLMREARLRMPRSIDSPGDIDTLVIVKRQGAAGGKGYFMANSEEEYESKRLSLIESGVISTDEDLYIQEYVPGVLAYLQFFYSPLKADIEFFGADQRHESDIEGLARIPAPVQMGSSGIPSFNVIGNSPLVLRESLLEGAYRMGEDFVEASSRLVAPGMNGPFCIEGVYGDDGRFTSFEFSARIVAGTNIYMNGSPYYGLLFDEPISMGRRIAREIKSAIAEERLDETVT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NTPPA_ECOL5
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKINGSFHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BACH_HALSD
Sequence: MMETAADALASGTVPLEMTQTQIFEAIQGDTLLASSLWINIALAGLSILLFVYMGRNLEDPRAQLIFVATLMVPLVSISSYTGLVSGLTVSFLEMPAGHALAGQEVLTPWGRYLTWALSTPMILVALGLLAGSNATKLFTAVTADIGMCVTGLAAALTTSSYLLRWVWYVISCAFFVVVLYVLLAEWAEDAEVAGTAEIFNTLKLLTVVLWLGYPIFWALGAEGLAVLDVAVTSWAYSGMDIVAKYLFAFLLLRWVVDNERTVAGMAAGLGAPLARCAPADD
What is the function of this protein?
Light-driven chloride pump.
What are the official names of this protein?
Halorhodopsin, HR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.