PharMolix/UniProtQA huggingface dataset:
Protein: URM1_BOMMO
Sequence: MAETLTVEVMFGGGAELLFNKVKRKEIALPPLKTFLPDSQNQNWTLKELLIWLKDNLLVEREELFLKDDSVRPGILVLINEEDWELHGQLNYELKENDKIMFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GWL_CHICK
Sequence: MSTVEPLSDEGVAAGPRRIEVPRPPSIEEFTIVKPISRGAFGKVYLGRKAGRLYAVKVMKKADMINKNMVHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEAALALDYLHRHGIIHRDLKPDNMLISNQGHIKLTDFGLSRVTLNREINMIDILTTPSMAKPKHDYSRTPGQLLSLISSLGFYTPVGMKMPINPNSGGASDSLHEVISPLSMIEKENTPLSTKLFKTGLDTSPLTPVMPVRSLTPALLQSRERFGASTASSQSCMYLSSMESECCSSPRLEKDVKQTEDEMCSTGTSNSRPPLPSSREVLNSKDPKVLKKELESAISPISSNDCGSRQKLGTERSEITDTPVTTLDTKGIVRKCLSENKIWEEKLVARREMTNEMLETASSQQSPLFLKDPVQPVKEEEIFEKPGVKRSFELVDTSPCQELNYVKKTNAEYKRGCWISELSASKSTGLTTEIQSLMLSGEICESKEIMRCIDRQQTEKPLVPTVAKNLLCDLDADHEKDKEYMNSSLLCADDEKPLGALSADSDLSFPETSVSESHLEKQLVDLDKGVKDLSFEEPKAEDLLTMSPNCQEASRNGVEADVVQNCTMLCCEQDNHQKHTEETDTISSPSEKMTETVHLFRKNNVVFRSYNSPINVSNVSDPCSMASLDIMDLSPACSGSYPTAITPLQKTPRQGDAGTPYRTPKSVRRGAAPVEGERILGTPDYLAPELLLTKPHGSAVDWWALGVCLFEFLTGIPPFNDETPAQVFQNILKRDIPWPEGEEKLSDNAQNAIDILLTFDSTKRAGLKELKHHPLFHGVDWDNLQNQPMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL
What is the function of this protein?
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance.  Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively.  ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A.  Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high.  Following DNA damage, it is also involved in checkpoint recovery by being inhibited (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase greatwall, GW, GWL, Microtubule-associated serine/threonine-protein kinase-like, MAST-L.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes.
Protein: GCH4_BORA1
Sequence: MNSPIDPAIVMPDVQSSADTRHIQIQRVGIRGVRHPMLVVAGDGSAQATVANWTLTVALPAEEKGTHMSRFVALLEKYRATPMTPALFSQMAREMLPLLHAERGDLTAAFPYFINKSAPVSGVQSLLDYEVIWTARAAGDEVEFELRVQVPVTSLCPCSKAISEYGAHNQRSHVTVSAVMEGDVAMDAIIRLVEDEGSCELWGLLKRPDEKYVTERAYDNPKFVEDLVRDVAARLKAHPSVARFCVEAENFESIHNHSAYAVVEG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: MODC_PHOLL
Sequence: MLELDFEQQLGDLYLQVNTQLPTEGITAVFGLSGAGKTSLINVIAGLIRPRKGRIVLNDHVLVDIEKGICLSPEQRRIGYVFQDARLFPHYRVKGNLQYGMSPEMKPEFDSIVSLLGIEHLLSRFPLTLSGGEKQRVAIGRALLTAPDLLLMDEPLASLDLPRKRELLPYLEKLSGEVNIPILYVSHNLDEILRLAENVLVVDNGKVRATGKLEEVWSSSALRLWLQKETLSSILNVSMVEHHNRYEMTAVALADQALWLPKMDVQPGTDLRIRIDASDVSLVLEPPRGSSIRNILAVKVVEFFDDNGHVDVKLVLSGHYLWARITPWARDELNLRSGQWLYAQIKSVSFHRQL
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSRB_PSEMY
Sequence: MDKVDKSLDTWREELTDEQFHVCRLGGTERPFTGAYHDSKTPGIYHCACCGEALFDSDAKYDSGSGWPSYFQPINDEVIASLDDYSHGMHRIEVKCAKCDAHLGHVFPDGPRPTGLRYCINSLSLKLVPRD
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: LPD6B_HUMAN
Sequence: MLYKSSDRPAHKVSMLLLCHALAIAVVQIVIFSESWAFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQNTQYCLTVHHFTSHGRSTSITKKCASRSECHFVGCHHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSAPTLYLPVLAWVFVLPLL
What is the function of this protein?
Likely acts as a modulator of nicotinic acetylcholine receptors (nAChRs) activity (PubMed:34631692, PubMed:26586467).  In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner (PubMed:26586467).  Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence (PubMed:26586467).  However, according to another report in vitro it can weakly inhibits alpha-7 nAChRs (PubMed:34631692).
What are the official names of this protein?
Ly6/PLAUR domain-containing protein 6B.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: SMYD2_CHICK
Sequence: MRSEAVPQPGGLERFASPGKGRGLRALRRYAVGELLFSCPAYTAVLTVSERGSHCDGCFARKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECAAMCAFGQNWNPSETVRLTARILAKQKIHPERTQSEKLLAVKEFESHLDKLDNEKRELIQNDIAALHHFYSKHMEYPDNAALVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVKEIEPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCDCRECTMKEKDKEKLKIRKLNDPPSAEAVRDMIKYARNVIEEFRRAKHYKPPSELLEICELSLDKMGAVFEDSNVYMLHMMYQAMGVCLYVQDWEGALRYGQKIIRPYSKHYPSYSLNVASMWLKLGRLYMALENRPAGDKALKKAIAIMEVAHGKDHPYISEIKKELEDH
What is the function of this protein?
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1.  Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo.  The activity requires interaction with HSP90alpha.  Shows even higher methyltransferase activity on p53/TP53.  Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.  Monomethylates RB1 at 'Lys-860'.
What are the official names of this protein?
N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, SET and MYND domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: CLPP1_BIFLO
Sequence: MASEEAKFAARADRLAGRQGVAGFMPASARAAQPAPTNRYIMPQFVEKTPYGMKTQDAYSRLFEDRIIFLGVQVDDASADDVMAQLLVLESQDPNRDVMMYINSPGGSMTAMTAIYDTMQYIKPDVQTVCLGQAASAAAILLASGTKGKRLMLPNARVLIHQPAIDQGFGKATEIEIQAKEMLRMREWLEETLAKHTGQDVEKIRRDIEVDTFLTAPEAKEYGIVDEVLEHRQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_SHEB2
Sequence: MINGSIVALITPMNSDGSVDFASLERLVEFHIDQGTDAIVAVGTTGESATLPMSEHVTVVSQTVKFAAGRVPVIGGNGANATSEAVELTKSLSKVGVAAMLGVTPYYNKPTPKGLIAHYKAVAASTDIPQILYNVPGRTAVDMLPETVAELVSVSNIIGVKEATGDLSRVKRLRELCGDDFLLYSGDDATAREFLLLGGNGVISVANNIVPQAFKAMCDAALAGNAELALSIDTPLRGLYSTLFCEANPIPVKWAAHRMGLIECGHIRLPLTELSEQCHGLLIEAMTRAQIEVK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOGA5_DANRE
Sequence: MSWFVDLAGKAEDFLNKVDQGAATALTKPNQKSSLSYNSPDATDSTQYNAAAYSSTQQHRDSISASSLGTSTFISAAAGNIKKSKATVLAGTANVSSTTPLGSSSKASSNFVRPRKSEVNDDLLFDFLNSSDPPQSEKKEVRRETVSKAFSPTGVSAQSQMPTVSLASDLHTGPSVTPTPSSTQGLSRNSSLGSLSSSSHSVKTEDSSTRDQSQADVPESLTAGLDDLADPQPVLEIQSQDLQQQQQQQGQEHVISNLRLENQLLRNEVSSLNQEMASLIQRAKDMQEEVNLGRARADKWNSDQSRVDRTVRELSSQVDDLTEALSAKDGQLAVLKVRLDEADQLLKARSSALEEAQNERVRILQDHSEGSSLHSQAVQTLQDRLRDAEAAVKREQESYRQIQSEFAARLAKVEAERQTLAESLTNAERRLTEEKQRAEDLQQQAKSSRSAAEYTKQELQDYKNKASRILQSKEKLINSLKEGSGLEVLEGAGAGVELEELRHEKELQREEIQKLQAQIQSLRTEIQDLETQALTENESWREQLAEVQEQHAQQIRAKQEIEAELERSKQELQYIEEEHHRTKITLQGRVKDREDEIQKLRNQLTNKALSNSSQAELEGRLHQLTETLIQKQTMLEALGTEKNSLVFQLERLEQQLKSLQGGQNSASHINMAAMEGPGARQRNTPILFSDGDGPGTGVYGKVRKAASTIDRFSIRLGIFLRRYPMARVFVIIYMALLHLWVMIVLLTYTPEMHHSHPDGR
What is the function of this protein?
Involved in maintaining Golgi structure.  Stimulates the formation of Golgi stacks and ribbons.  Involved in intra-Golgi retrograde transport (By similarity).
What are the official names of this protein?
Golgin subfamily A member 5, Golgin-84.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: NUMB1_CAEEL
Sequence: MSASQGNVFTRGLSRISRRKKKTKSIQNSLVSEQQPSFDAAIVPMPIPNDKSSIFSKGMDRLRRSLRLPKKRRDRSHDRHLSPDVTGGSKTEQWQPDEGAVRTGTCCFNVKYLGSVEVYESRGMQVCEGALKSLKASRRKPVKAVLYVSGDGLRVVDQGNSRGLLVDQTIEKVSFCAPDRQTDKGFAYICRDGASRRWMCHGFLATKETGERLSHAVGCAFSICLEKKKRRDEETAQVNVQSAQESTSSTPPKDIFHPNWEDNTSEGTSTQNPSNSRSNLAYQSFRKHVSIEDRYLDPQSVIINEVPASNHMDEIRRISKPRPTGNPALFLRQGSLRAPPDMPSSSDQFKRNMSLRTVSNNPTERSPEKKSFGTQLYNEPIYEGDEDPLGLGITPPVVTKTSGSLSNNGLDGINLNWKSIPAPVHQMQQHNANGDFVAAWPQNTIEKPTVGPLDKLQKQFEDIKLISISSGENTPTTRSKADEWLDDVLRVSMSMSPTSPSSDPPSTSSYSVLPKSGPPPAHAPPPLPVRQAVSNGSPSIYQQQLQQANSTRNSPAGINWNSSPNPMKISQPPAKPVDPFDVQWSRLAVNNTH
What is the function of this protein?
Involved in the tethering and targeting of pkc-3 to modulate the intracellular distribution of the kinase.  The complex formed with pkc-3 complexes are likely to be involved in assembly, maintenance, and/or regulation of protein complexes that execute asymmetric and/or polarized cell functions.
What are the official names of this protein?
Numb-related protein 1, CKA1, Protein kinase C adapter 1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Expressed at the inner surface of the plasma membrane at the cell periphery (which includes a region corresponding to plasma membrane and/or actin cortical cytoskeleton) in early embryos. Tightly associated with organelles and/or cytoskeletal structures with some diffuse expression in the cytoplasm. Differentially routed to lateral junctions between polarized cells.
Protein: QUEF_VIBCH
Sequence: MSKYSDAKELASLTLGKKTEYANQYDPSLLQPVPRSLNRNDLHLSATLPFQGCDIWTLYELSWLNQKGLPQVAIGEVSIPATSANLIESKSFKLYLNSYNQTRFASWDEVQTRLVHDLSACAGETVTVNVKSLNEYTAEPIVTMQGECIDDQDIEIANYEFDDALLQGAAQGEEVSEVLHSHLLKSNCLITNQPDWGSVEIAYHGAKMNREALLRYLVSFREHNEFHEQCVERIFTDIMRYCQPQSLTVYARYTRRGGLDINPFRSSHQSAPNHNQRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_RICTY
Sequence: MTIQYTFSMIKPDVIKRNKIGQVNTYLENAGLKIVAQKMKFLTKYEAECFYDEHRARPFFNSLVEYITSGAVVLQVLKGEDAITLNRIIMGATNPAEAKEGTIRKDLGESIEANSIHGSDSENSAKREIKFFFSKSEIIE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_STRPF
Sequence: MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGMQDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPDEDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAVLPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDYDDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAFDWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NATTJ
Sequence: MLMPKRTKFRRQMRGRMKGKAKGGKEIAFGEFGLQALEPAWINSRQIEAARIALTRYIKRGGKVWVKIFPDKPVTQKPAETRMGGGKGSPEFWAAVVKPGRILFEVAGVPKETAREAMRLASHKLPIKTKFVEREEMGGDANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NADM_METBF
Sequence: MTRAFYIGRFQPYHFGHHTIIKQIAEEVDELVVGIGSAQKSHESTDPFTAGERVLMVYNALENLPIRHYVLPIEDIKYNSIWVHHVASRTPHFEVVYSNNPLVIQLFREAGVCVKQSPLYIRERYSGTEIRRRMIAGEKWEHLVPKSVVEVIKEIDGVTRLRNVSASDNNSSL
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_SACHY
Sequence: MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSSGNEHPKPKGFSGQQANK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRD_ACIF5
Sequence: MSYGLLRPLLFTLDPERAHTLSIAALEALGHMPRGLARVARRYTAHDPRLAQDFWGLHFANPVGLAAGYDKDARATAALPALGFGFIEIGTVTPRPQPGNPRPRVFRYPAQQAVINRMGFPGEGAAAVARRLAALPGHPVPIGINLGKNKDTPLERAQDDYVAALELLFHYGDYLCINVSSPNTPGLRLLQGEEALRGLLKAVAAANQRLALQHQRPPLPLLLKIAPDLDNDDLNAIGSLALGTAPLVNGFIATNTTIERPASQPGLSESGGLSGAPLLQQSNAVIAQLYRATQGQVPIIGVGGILSAADAYAKILAGASLVQVYSGLIFRGPGLVREILEELPGLWLKDGYPDLAHARGSTA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPS3_THYCA
Sequence: MSTISIHHVGILRNPLHSKSKRASINKPWSLSLPRSSSASRLVEPCRVSSKTDTKPAEITRRSGNYEPSLWDFDFIQSLDNHHPYVKEKQLKREEELIVQVKMLLGTKMEAVKQLELIDDLKNLGLSYFFRDEIKTILTSIYNNSFENKNNQVGDLYFTSLGFRLLRQHGFNVSQDIFDCFKNEKGSDFDETLIGEDTKATLQLYEVSFHLREGENTLELARQISTKYLQKQVNEGRISDENLSLWIRHSLDLPLHWRIQRLEARWFLDAYAAREDKNPLIFKLAKLDFNIIQATQQEELKEVSRWWNDSCLAEKLPFVRDRVVESYFWGVGLFEGHEFGYQRKLTAAYILLISAIDDVYDVYGTLDELRLFTDVFRRWDTESIDQLPYYMQLCYLALHNYVSGVAYDILKDHRRNTIPYLQETWVELVEAYMKEAEWYQSGYTPSLEEYLTIAKISIGSLPILLSVELSLPDSTIDRATFDRRHKMFYLSATVSRLADDLGTAPSELERGDVPKAIQCYMKDTNASEEEAQGHVRFMIREAWKELNTAMAEPDDCPFTEQVVEATANIGRAAQYIYREGDGHGHFQIRQHVRNLFFHPYV
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products (PubMed:23624978).  Monoterpene synthase which catalyzes the conversion of geranyl diphosphate (GPP) to alpha-terpineol (isomer is not determined) (PubMed:23624978).
What are the official names of this protein?
Alpha-terpineol synthase, chloroplastic, Terpene synthase 5, TcTPS5.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDD_STAAC
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPO77_YEAST
Sequence: MFRRGDNSNFNVQNSFFLPLEYEYTVKDNVPSKKKSSIGFFPLDDSLFTSKNNSGHHKSEQLHRGNAETIRSQFGTDAVPIRIDEKEGKWDRIQDDNSSNLNYQINNSNDPASSGKYTQSIDCNHIAESKFSKKNGNIDSLRSNSATFMLNTADEDVIEFSFDDNVPYAELLSGATLEKCSLTLNEINKKLFNTLYDFRVSKDNPEENLVELILPNCVVLLNFFEDIELLADSSDEAFEKSTFINTIEFIVHDIWVETLIKNINLLQMFDADLKCYNDKYIICKLKGQYPSTNIVDIMCRLKHFSNSILETFKFGIELKEQDQCHNRNTIINYVLFSRVFSTIVLEIQKCFILIVKFMYSVNFLEKFSDEVFLSFIEILIKIVFEHQIPQLFLGIDEIIQLWLKNNEGKRQQLLSAWCNGTVQDMKQSQQRESSNAESESITSSTEEDEEGLQFNKWDVIEPFIDNIKALNQSKSHM
What is the function of this protein?
Required for spore wall assembly and ascus formation.
What are the official names of this protein?
Sporulation-specific protein 77.
What are the subcellular locations of this protein?
Cytoplasm. Note=Diffuse location throughout the cell at all stages of sporulation.
Protein: CB078_HUMAN
Sequence: MHWLASATQTSASIVSSSLLSAVDVSSSLTMSEYFQNTSLPGTANSRQFSLPVVSNAAFLTGSISNFSRASAPAISSAWLQPSASGTSFQPLMGSAYLYQHSSTTMLSGVTGQSHICTSAASYPGVFEWDSTASTVKKSSSLRDFTVTVIDQNTAVSSMSMTAQYYKTSDTNTMVPLYPSLSASLVQGTLTQIPNQQGHNLSLPCQIGSQVYYYNQGTLGPQLSCLQSYGSVSYTGYRASAHQPEMVMVLKEVQPTNVLPPVSTSGMYYSVSSQPITETSVQVMETSLGMDTSLGLQSPSQTFCLPQTPEFSKSFSSRNTQTLESNPSPELGDISITPVQSPTNLLTLSPAPSQEKNENENLDEIKTNLSKPLDVHQILIGNQDPPLLPVEIPDIHPLLACIDPLGQEEQPGSENANLRNKSLSLEDQGIFENGIESSSDLADITTWVEDTYLPPIFSSLQDLDQPESPSAKKAKDTSAIKVNQVQEKSCVIKGHSDQVRKNKHKASEPIQGAPKAKIQPKNPECLLEREVVVGSATVSNSASVNKAKHSSNKPHKAASSRISKTKSHGQEKTKGNRKNSSKKSEESKQSGKKVKVEEKQTIPNMKRKKNQPELSQKTLKKPRSSLGMHMLESVQVFHALGKKIDMKTGFSSSRTLGSSSNTQNRQPFPALKPWLDIQHEGKGPEKIQVKAQKLDGSAEKECTSPSHSELPPPGKVKLIPLPFLTLDQPQARHVSRRPNPLASRRPAVAYPARPDSTNSAQSNAVNPSRPAPTNTSLTGPATPAQPISAKATQPSSANPTQPTVPQSAASRPSAYKTSSCSSLQREPVSTAVTSLRSLPKPQNQFLIQDFSLQPRPWRKPTVPEPVMSTPITEEQRPEREAMKRKAQQERENAAKYTSLGKVQFFIERERDMEIAEYYGYTI
What are the official names of this protein?
Uncharacterized protein C2orf78.
Protein: C1QB_RAT
Sequence: MKTQWSEILTPLLLLLLGLLHVSWAQSSCTGSPGIPGVPGIPGVPGSDGKPGTPGIKGEKGLPGLAGDHGELGEKGDAGIPGIPGKVGPKGPVGPKGAPGPPGPRGPKGGSGDYKATQKVAFSALRTVNSALRPNQAIRFEKVITNVNDNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNIVRGRDRDRMQKVLTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGVEGANSIFTGFLLFPDMDV
What is the function of this protein?
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.  The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
What are the official names of this protein?
Complement C1q subcomponent subunit B.
What are the subcellular locations of this protein?
Secreted.
Protein: KCY_THENN
Sequence: MGFQIAIDGPAASGKSTIAKLLAERLGFEHLNTGATYRAVAVYLKEKGLNPSSPREELEKALKDVKVDYRDGRVFINGKDYTEKIQSPEAGILASDFAKLDLVREHLVRIQREICDDKNIVVEGRDIGTVVLPDAQLKIFLTASLEARIERKLREYQKKGLNVSREEVERELISRDTQDSSRKIAPLKPAEDAVVIDTTSMSVNEVLQKILKLVEERMKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB1_BACCR
Sequence: MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKWTVIGRGSNLLVSDQGIEGVVIRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGAIDWLTNKELEFSYRASVLQTKRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVEKAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIGR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase 1, UDP-N-acetylmuramate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STS1_COLGM
Sequence: MNVLLSPQPPLFQHPHETNRISPSRSLSPFHNMSTSRKRKADEDGDEMSMSPRSSPAASSRQLQRPSKKVRSNELVGRPLTLPRLLETLDPTALRTVLERICERHPDIGQEVVNSAPRPTVAAAHGVLQEYQDKMKAAIPYGETSPDYTYYRVKAPMTALIDALLDFTPQYLPPNETQTTVSLQYMDGATKIIHALPDWEPQQYRHHKENAYDEISKAWALVINEAAKRGGGLSLHTGGWDQTLAKHHEISGGRMGTAMNAMATSVSWMAHGGSSNGQQPGNPSSDQNSILNQLMSGTYGAPVRVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOC_STAEQ
Sequence: MIDVNNFHYMKIGLASPEKIRSWSYGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFREYYDKYPNQFVAKMGAEGIKDLLEEIDLDEELKELRDELESATGQRLTRAIKRLEVVESFRNSGNNPSWMILDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVLEDVITEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNDTNEVLKAYANGYVHLHTRIGVHANSFNNPTFTDEQNSKILATSVGKIIFNEIIPDSFAYINEPSQANLERTTPDKYFVDPTQLGEGGLKEYFDNTELIEPFNKKFLGNIIAEVFNRFSITDTSMMLDRMKDLGFKFSSKAGITVGVSDIVVLPDKQDILDEHEKLVERVTKQYNRGLITEDERYNAVVEIWTDAKDQIQGELMQSLEKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEVIIRPDELITPDIAKQITDAGIEQMYIRSAFTCNTRHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGVVDDIKLAKDRQQEIIVKGANETRSYLASGTSRLKVEIGQSVERGEVLTEGSIEPKNYLSVAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANRDAFKHRKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKENVIIGKLIPAGTGMRRYSDIQYDKATAPVTETSEEVETIE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.