PharMolix/UniProtQA huggingface dataset:
Protein: PCHE_PSEAB
Sequence: MDLPPDSRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTVQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFFDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLARRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSTWEQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVDAADRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDAHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWDDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMELPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPPLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYAASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGECRDEPSAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQAQTVEIEETQLEEGVL
What is the function of this protein?
Involved in the biosynthesis of the siderophore pyochelin (PubMed:10555976).  Accepts salicylate activated by PchD at the first peptidyl carrier domain (ArCP), and activates and fixes one molecule of cysteine at the second peptidyl carrier domain (PCP1) via a thioester linkage to the phosphopanthetheine moiety (PubMed:10555976).  Then catalyzes the condensation reaction between the salicylate bound to the first site and the cysteine bound to the second site, and the cyclization of the cysteine to form the salicyl-thiazolinyl-S-PCP1 intermediate at the second site (PubMed:10555976).  When this intermediate is released by the action of a thioesterase, it produces the antifungal antibiotic dihydroaeruginoic acid (Dha or hydroxyphenyl-thiazolinyl-carboxylate) (By similarity).
What are the official names of this protein?
Pyochelin synthase PchE, L-cysteine--[L-cysteinyl-carrier protein] ligase, Nonribosomal peptide synthase PchE.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: NIFD_FRAAL
Sequence: MTTTPAPERAETEAMIAEVLSQYPKKAAKFRAKHLKANDPEGSKECEVKSNIKSRPGVMTIRGCAYAGSKGVVWGPVKDMVTISHGPVGCGQYSWATRRNYAHGHLGVDNFTAMQITTDFQEKDIVFGGDPKLEQGLDEIVELFPLAKGISVQSECPIGLIGDDIEAVARVSSRLDIPVMRVRCEGFRGVSQSLGHHIANDAVRDHVLGTGGDSFEQTDYDVALIGDYNIGGDAWASRRILEEMGLRVIAQWSGDGTINEMASTHLSKLNLIHCYRSMNYICTTMEERFGTPWTEFNFFGPTKIISSMRKIAEFFDDEIKAKNRAAIAGYQRCVDEITKAFRPRLEGKRVMLAVGPAPRHTIGSYEDLGMEVVGTAAEFAHRDDYTGPTACSKEGTGLYDDPSRVFELEEVAKRPDLIGSGPKEKYIFQKMGTPIEPYHGVDGFAIFARDMARHQQPGLDLLEAPWSKAGEVA
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: RPOC_CHLCH
Sequence: MILSQGTSPLKGDFSRIKFSIASPESILAHSRGEVLKPETINYRTFKPERDGLMCEKIFGPTKDWECYCGKYKRVRYKGIICDRCGVEVTTKSVRRERMGHISLAVPVVHTWFFRSVPSKIGALLDLSTKELERIIYYEVYVVINPGEPGEKQGIKKLDRLTEEQYFQIITEYEDNQDLDDHDPNKFVAKMGGEAIHMLLKNIDLDETAVHLRTVLRESNSEQKRTDALKRLKVVESFRKSYEPHKKSRKKPNALFAEDDMPEPYVYEGNKPEYMVMEVIPVIPPELRPLVPLEGGRFATSDLNDLYRRVIIRNNRLKKLIDIRAPEVILRNEKRMLQEAVDALFDNSRKANAVKTGESNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHECGLPKSMAIELFQPFVIRRLVDRGIAKSVKSAKKLIDRKDPVVWDVLEKVIDGRPVMLNRAPTLHRLGIQAFQPHLVEGKAIQIHPLVCTAFNADFDGDQMAVHIPLSQEAQLEASLLMLSAHNLILPQSGKPVTVPSQDMVLGMYYLTKSRGGEMGEGRIFYSAEEVRIAYNEQLVGLHAQIFMRYDGQVDQKFDAIRVMETFVEPTSEKAAWLRKQLDEKRMVLTTVGRVIFNQHVPESIGFINRVIDKKVAKELIGRLSSEVGNVETAKFLDNIKEVGFHYAMKGGLSVGLSDAIVPETKAKHIKNAQRDSTKVVKEYNRGTLTDNERYNQIVDVWQKTSNIVAEESYQKLKRDREGFNPLYMMLDSGARGSREQVRQLTGMRGLIARPQKSMSGQPGEIIENPIISNLKEGLTVLEYFISTHGARKGLSDTSLKTADAGYLTRRLHDVAQDVIVTIDDCGTTRGLYVHRNIEEETSGQIKFREKIKGRVAARDIVDTVTGNVLVQAGEIITEELADSIQETAGVEEAEIRSVLTCESKVGICSKCYGTNLSVHQLVEIGEAVGVIAAQSIGEPGTQLTLRTFHQGGAAQGGISETETKAFCDGQVQFEDVKTVAHTAMNEDGMEDVRTIVIQKNGKINIIDSESGKLLKRYMLPHGAHLACEDGVLVKKDQVLFRSEPNSTQIIAELPGTIKFADIEKGVTYKEEVDPQTGFSQHTIINWRTKLRATETREPRLLILDENGEVRKTYPVPIKSNLYVEDGQKVLPGDILAKVPRNLDRVGGDITAGLPKVTELFEARIPTDPAIVSEIDGYVSFGAQRRSSKEIKVKNDFGEEKVYYVQVGKHVLANEGDEVKAGDPLTDGAVSPQDILRIQGPNAVQQYLVNEIQKVYQINAGVEINDKHLEVIVRQMLQKVRIEEPGDTDLLPGDLIDRSAFIEANRAISEKVRISERGDAPARIQENQLHKLRDITKLNRELRKNSKKMVAYEPALQATSHPVLLGITSAALQTESVISAASFQETTKVLTDAAVAGKVDYLVGLKENVIVGKLIPAGTGLKKYKTIKLVGEESAPAPVVVEAVVSHEAEASPMVEEEVAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SLD1_KLULA
Sequence: MSRVLSRRDIADRIAKGQTIVIYEDSVLNLDKWIKFHPGGDKSIYHMIGRDATDEMNAYHDDQTITKFKIWKIGRIDYPWENMLPPIQGGRFSKIDERDDIGDYDINLTSKWRSVDESNQYTKIPKNDRLASEAEVKIYPKIPQGVVPSLDLKEAYEKKIVVDPAIVSENYDNERVYEDLTNFPSLDVKNQEWIASEYRKLHGEITAAGLYQCNYVRYLKEFLRIGTLFGISFYLLSLKWFAISAICLGFAWQQLVFIAHDAGHISITHNYQVDNIIGMTVASWIGGLSLGWWKRNHNVHHLVTNDPVHDPDIQHLPFFAVSTRLFHNVYSTYYDKFLWFDKFAQKVVPIQHYLYYPILCFGRFNLYRLSWMHVLLGQGPRRGKAAWFRYYELAGLSFFNYWFFYLIIYKQMPTNAERFKYVMISHIATMIVHVQITLSHFAMSTSDLGVTESFPMRQLRTSMDVDCPRWLDFFHGGLQFQVIHHLFPRLPRHNLRDAQSLVIKFCDKVGIKYSIYGFAAGNDVVISHLQQIAQQAHTMLECAKTMKKEATDTEFHTNKHVLAANVNEKRKQE
What is the function of this protein?
Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides.  Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.
What are the official names of this protein?
Delta 8-(E)-sphingolipid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NQRB_PSEMY
Sequence: MGIRAFLDKIEHNFEKGGKYEKWYALYEAIDTFFYRPGSVTKTTAHVRDGIDLKRMMITVWLCTFPAMFFGMWNTGYQANLIFAQSPELLASQEGWRFALIGSLAGFDPNSLWDNFIQGAAYFLPVYAVTFIVGGFWEVLFASIRKHEVNEGFFVTSVLFALILPPSIPLWQVALGISFGVVIGKEVFGGTGKNFLNPALTGRAFLFFAYPAQMSGDAVWTAVDGFAGATSLSLAASGGIENVINNGITWMDAFIGTIHGSLGETSTLAIAIGGLVLLITKIASWRIVSGVMLGMIGLSLLLNLIGSNTNPMFAMPWYWHLVVGGFAFGMFFMATDPVSASMTNTGKWIFGALIGVMVVLIRVVNPAFPEGMMLAILFANLFAPLIDHFVVQANIKRRLARNV
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_CLOP1
Sequence: MLKNKHLLDPSDFTIEEFDEIFKLAHQIMANPKEYQNICNGKILATLFYEPSTRTRLSFESAMLRLGGQVIGFSEPNSSSVSKGESLRDTIKTVNCYADLIAMRHPLEGAAKVASMYSDIPVINAGDGGHQHPTQTLTDLLTIKEYKGNLEGNTIALCGDLKFGRTVHSLIKALSRYKNNKFILISPIELRIPNYIREQILEKNNIEYKEITSLEEGIKEADILYMTRIQRERFVDQSEYERLKDVYVLDEAKMKGAKEDMMVLHPLPRVNEIAYEVDEDSRAFYFKQAKCGMYVRMALMAKLLGEA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: DCUC_VIBCH
Sequence: MEIAMLELLIGLVVTFAVGYFIVKGYKPAGILLTAGILLLILTGILGHKVLPGQMESTGNLLTDAMEYVKYMLQNRGGGLGMQIMLLCGFASYMTHIGANNVVVKQFSKPLSFIKSPYILLVAAYLVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAVAVCASPAAIILSPTSGDVVIAAEKSGLPLHVFAVETVLPVSICAIIVMAAAAYFWNQYLDKKDNTPMEKVDLSEMEVKSPAYYAVLPFLPIIGVFVFNGETLPGITLDIYTIVVLSIFIGVLVDYITKRFNGKQTLEDLEACYEGMADAFKGVVMLLVAAGVFAQGLMSIGAIDNLLHLAEVAGAGGIALMLILTGLTVAAAIATGSGNAPFYAFVELAPSLAAKMGLNPAFLIIPMLQASNLGRTISPVSGVVVATAGMGKISPFEVVKRTSVPVLLGLVTVIIGTMVLVPMHA
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during anaerobic growth.  Catalyzes the uptake of fumarate coupled to the export of succinate.
What are the official names of this protein?
Probable anaerobic C4-dicarboxylate transporter DcuC.
What is the protein family that this protein belongs to?
Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLND_HAEIE
Sequence: MLFPLSLSSPLTPSAVKIERENLKQFELENFSRYSIFELVENRSDFYDALLIQLWQEMGLSEQLGISLIAVGGYGRREMFPLSDLDFLILVEQTPIPEIEEKITQFIQFLWDCGFEVGHSVRTLQQCESEGKQDITIATNLLEARFLIGNRPHFDALNELVKRADFWSKEGFFNAKVQEQIERYQRYHNTAYNLEPDIKYSPGGLRDLHLLYWVALHHSGAQTLEDILQSGFIYPQEYQQLQESRAFLFKVRFALHLILTRYDNRLLFDRQIKVSELLGFRGEGNQAVEKMMKCFFQALHRISLISNLLIQHYRENVLSSNQATVIEQLDDDFQLINQCLCLRNSLVFQEKPARILDLFFYLTQYEQANIHSDTLRQLQISLEQLPQKLCEIPEAREKFLRLFNQPNSIKRAFMPMHQYGVLTAYLPQWQAIEGLMQFDLFHIYTVDEHTLRVMLKLESFLSQESAQEHPIAHRIFSQLSDRTLLYIAALFHDIAKGRGGDHAELGAKDVANFARLHGLDRREIDTLAWLVQSHLLMSITAQRRDIHDPEVVMNFAEAVQNQVRLDYLTCLTVADICATNGNLWNSWKRSLFASLYEFTEQQFAQGMKELLDYSEKSAENRKLAQQILTQDYSDIMPISIDQLWERCPEDYFVRNTPKQIAWHTSLLVDLVEALLVKISNRFSLGGTEVFIYCQDQPHLFNKVVSTIGAKKFSIHDAQIITTQDGYVFDSFIITELNGELVEFDRRRELEQALTLALQSEKLSALSITPNRQLQHFTVQTDVRFLHENKKEHTEMELVALDKAGLLAQVSQIFSELNLNLLNAKITTVGEKAEDFFILTNQFGQALDSQQREILRNVLYRNIG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: NRFA_BACFN
Sequence: MEKKLKSWQGWLLFCGAMAVVFVLGLVVSSLMERRAETVSVFNNKRVEITGIEARNEVFGENYPRQYETWKETAKTDFKSEFNGNEAVDVLEQRPEMVVLWAGYAFSKDYSTPRGHMHAIEDITHSLRTGAPMDDKSGPQPSTCWTCKSPDVPRMMEAIGVDSFYNNKWGAFGSEIVNPIGCADCHEPTNMKLHISRPALREAFARQGKDIDKATPQEMRSLVCAQCHVEYYFKGDGKYLTFPWDKGFSVEDMEAYYDEADFADYTHALSKARILKAQHPDYEISQMGIHAQRGVSCADCHMPYKSEGGMKFSDHHIQSPLAMIDRTCQVCHRESEETLRNNVYDRQRKANEIRGRLEQELAKAHIEAKFAWDKGATDVQMAEALKLIRQAQWRWDFGVASHGGAFHAPQEIQRILGHGLDKALQARLAISKVLAQHGYTADVPMPDISTKEKAQEYIGLDMEKERKAKDKFLKTIVPEWLEKARANGRLAKL
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MYB93_ARATH
Sequence: MGRSPCCDENGLKKGPWTPEEDQKLIDYIHKHGHGSWRALPKLADLNRCGKSCRLRWTNYLRPDIKRGKFSAEEEQTILHLHSILGNKWSAIATHLQGRTDNEIKNFWNTHLKKKLIQMGIDPVTHQPRTDLFASLPQLIALANLKDLIEQTSQFSSMQGEAAQLANLQYLQRMFNSSASLTNNNGNNFSPSSILDIDQHHAMNLLNSMVSWNKDQNPAFDPVLELEANDQNQDLFPLGFIIDQPTQPLQQQKYHLNNSPSELPSQGDPLLDHVPFSLQTPLNSEDHFIDNLVKHPTDHEHEHDDNPSSWVLPSLIDNNPKTVTSSLPHNNPADASSSSSYGGCEAASFYWPDICFDESLMNVIS
What is the function of this protein?
Transcription factor that acts as negative regulator of lateral root (LR) development.  Required for normal auxin responses during LR development.  May be part of a negative feedback loop stimulated specifically in the endodermis upon LR initiation to ensure that LRs are formed only in the correct place.
What are the official names of this protein?
Transcription factor MYB93, Myb-related protein 93, AtMYB93.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RUVC_ECO57
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RLMG_PSESH
Sequence: MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAETGLSLQSRVLVLNDSFGALAASLASHATVVSSTDSFLAAQGLEKNLARNGMSYDAVPHIPASEPLSGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVVAAAMVKHLPRSAGDLLEEYVGPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLDEPAIELLNHANVFCRDGLDIGTRAFLPYLPKNLGTARVADLGCGNGVLAIASALDNPQAHYTLVDESFMAVQSAAENWRATLGERVVEVRAADGLDTQEPDSLDVVLCNPPFHQQQVVGDFLAWRMFLQARAALVNGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM746_CONIN
Sequence: CCEWPCHHGCIPCCY
What is the function of this protein?
Probable neurotoxin with unknown target (Probable).  Possibly targets ion channels (Probable).  In vivo, intraperitoneal injection into fish provokes paralysis after 5 minutes (By similarity).
What are the official names of this protein?
Conotoxin In1746, Conotoxin In1762.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHLN_CYAPA
Sequence: MNQINNSTLTFQCETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNSMGVMIFAEPRYAMAELEEGDISAQINDYEELKRLCTQIKNDRNPSVIVFIGTCTTEIIKMDLEGIAPKLEAEIGIPIVVARANGLDYTFTQGEDTVLASLIQRCPSKDRETEKINKNNSSLFPSLSIFSKNKNESNLSQDKPNLPLVLFGSLPNSLTNQLEHELEKQNIKISGWLPTKNYKELPVIHEGDYVCGVNPYLARTATNLIRRRKCKLISAPFPIGPDGTRAWIEKICSIFNIEPTGLDEREKAVWDSLENYLPLVKGKSVFFMGDNLLELSIARFLIRCGMIVPEIGIPYLHKRYQEAEIKLLEDTCRKMQVPTPLIIEKPDNYEELKRIEQYRPDLVITGMANANPLEARGINTKWSVEFTFAQIHGFSNARDILELVTRSLRRKNYIQQLGWKELVE
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: ALKB2_BOVIN
Sequence: MDRFLVKGAVGSLKRRMEQEQTGGGPAGLAEEEGNSKKNPRRAAPGNGVDSAGLTWGRIRAEGLNCDYTILFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDTGLTYTFSGLTLSPKPWIPVLERVRDRVSLVTGQTFNFVLINRYKDGQDHIGEHRDDERELALGSPIASVSFGACRDFVFRHKDSRGKHPSRRLEVVRLQLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILPTTKRTTLLTASASVGSFALHS
What is the function of this protein?
Dioxygenase that repairs alkylated nucleic acid bases by direct reversal oxidative dealkylation.  Can process both double-stranded (ds) and single-stranded (ss) DNA substrates, with a strong preference for dsDNA (By similarity).  Uses molecular oxygen, 2-oxoglutarate and iron as cofactors to oxidize the alkyl groups that are subsequently released as aldehydes, regenerating the undamaged bases.  Probes the base pair stability, locates a weakened base pair and flips the damaged base to accommodate the lesion in its active site for efficient catalysis (By similarity).  Repairs monoalkylated bases, specifically N1-methyladenine and N3-methylcytosine, as well as higher order alkyl adducts such as bases modified with exocyclic bridged adducts known as etheno adducts including 1,N6-ethenoadenine, 3,N4-ethenocytosine and 1,N2-ethenoguanine (By similarity).  Acts as a gatekeeper of genomic integrity under alkylation stress.  Efficiently repairs alkylated lesions in ribosomal DNA (rDNA).  These lesions can cause ss- and dsDNA strand breaks that severely impair rDNA transcription (By similarity).  In a response mechanism to DNA damage, associates with PCNA at replication forks to repair alkylated adducts prior to replication (By similarity).
What are the official names of this protein?
DNA oxidative demethylase ALKBH2, Alkylated DNA repair protein alkB homolog 2, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Relocates to the replication foci during S-phase.
Protein: RBSA_ECOUT
Sequence: MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQFIAEREVASLTEDSLIEMMVGRKLEDQYPHLNKAPGDIRLKVDNLCGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIILVSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL1_DESVV
Sequence: MPKHGKKYRNATEGLDLTVKYSVEDAVAKSLAAAPAKFDETVDVAICLGVDPKYSDQMVRGAVTMPNGLGKTVRVAVFCKGEKEAEAKAAGADVAGAEELVAKIKEGWLDFDKAIATPDVMALVGQIGRVLGPRGLMPNAKTGTVTFDITTAIKEMKAGRVEFKVDKAGVLHAPLGKVSFGSEKILGNLKALIDTVNRLKPSSAKGTYMQAMAISTTMGPGVKVDPTLIKKFIEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DED1_AJECN
Sequence: MANGLNIGSLKIDDSQRPAGPNTTGRAAYIPPHLRGSVARPPMGLDGSGPAQAVPGLNASTWAPNNAGPHPGAGHNWANAQNFTPRDRPPGAPAGPPSMNGNTTWGNAPPRQFNANDYGKPGPNSFRGSSYGGGRSGGTRGIGGHGYWDENGKHAQGPENKRLERELFGEADDPTKQHTGINFSNYDSIPVEASGHDVPESITAFTNPPLHEHLLSNIVLARYTVPTPVQKYSIPIVMGGRDLMACAQTGSGKTGGFLFPILSQSLHTRGPEAEAARGLGRQQKAYPTALILGPTRELVSQIYDEARKFCYRTALHPRVVYGGAEMGNQLRQLDQGCNVLVATPGRLVDMMERGRISLAHIQYLVLDEADRMLDMGFEPQIRRIVQGSDMPDKHMRQTLMFSATFPPDIQKLAEEFLKDHIFLSVGRVGSTSENITQRIVECESDKDKDSALLDILCSDSTGLTLVFVETKRQADMLSDFLLDHRLPATAIHGDRTQRERERALELFRTGRCPILVATAVAARGLDIPNVTHVINYDLPNEIDDYVHRIGRTGRAGNTGISTAFFSRSKNFKIARSLVDLLKDANQEVPDFLEKLGRQGNYYGSSGGGRGGRGGGRGRGGSSSTRDIRRTGGGYGGGGMGGSRPAYGGGYGDSGAGGPYGYGGGSGGYGGGYGGGYGGGGYGNPSGPTGPSSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DED1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1181_STRPG
Sequence: MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASQLFDEFVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIERIVFAPLKDLVK
What are the official names of this protein?
UPF0342 protein SpyM51181.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: CY561_PONAB
Sequence: MEGGAAASTPAALPYYVAFSQLLGLTLVAMTGAWLGLYRGGIAWESDLQFNAHPLCMVIGLIFLQGDALLVYRVFRNEAKRTTKVLHGLLHIFALVIALVGLVAVFDYHRKEGYADLYSLHSWCGILVFVLYFVQWLVGFSFFLFPGASFSLRSRYRPQHIFFGATIFLLSVGTALLGLKEALLFKLRDKYSAFEPEGVLANVLGLLLACFGGAVLYILTRADWKRPSQAEEQALSMDFKTLTEGDSPGSQ
What is the function of this protein?
Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles.  It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes.
What are the official names of this protein?
Transmembrane ascorbate-dependent reductase CYB561, Cytochrome b-561, Cytochrome b561.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein. Note=Secretory vesicle containing catecholamines and amidated peptides.
Protein: GALE_DICDI
Sequence: MEPIDDRIMVTGGAGYIGSHTVIELIEAGYTPVIVDNLSNSSLEAIKRVESITGKEIEFHHVDIMNEKALDEIFETGNIRSVIHFAGLKAVGESNKLPLKYYNNNIAGTLTLLNLMDKHRVKKLVFSSSATVYGDPHTVPITEDFPLSATNPYGRTKLYVEGILQDLCASDPEWNCIMLRYFNPVGAHPSGLIGEDPKDIPNNLMPYVTQTAIGKRPILSIFGNDYNTPDGTGVRDFIHVVDLAKGHISALSSLHSKKQGCVAYNLGTGRGYSVLEMVGALKQASHKEIPYQIVSRRKGDVASSFADPSKALKELGWKATHNQDDMCRDAWKWQSLNPNGYSDS
What is the function of this protein?
Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.  The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate.  It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited.  Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.