PharMolix/UniProtQA huggingface dataset:
Protein: ESPG1_MYCMM
Sequence: MTGPLATGRAGTGDDVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIPQEDLREIVWDQVARDLTAQGVLDHNGQPHPAVAAMVDTLSRADRTLEGRWWRRDVGGVMVRFVVCRKGERHVIAVRDGDMLVLQLVAPRVGLAGMVTAVLGTAEPANVEPLTGIASELGECTNAAQLTRYGLTPTTARLYTEIVTNPKSWVEIVASERHPGGTTTHTKAAAGVLDSAHGRLVSLPRQVGGELYGSFLPGTEQNLQRALDSLLELLPSGSWLDRADATARG
What is the function of this protein?
Specific chaperone for cognate PE/PPE proteins (PubMed:22843727).  Plays an important role in preventing aggregation of PE/PPE dimers (By similarity).
What are the official names of this protein?
ESX-1 secretion-associated protein EspG1.
What is the protein family that this protein belongs to?
Belongs to the EspG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMT5_CANAL
Sequence: MTKELPSGYFQGPFRPYKTFQPSLTERPLSKFEQFAVFSILLISLIRLYKLYIPDRVVFDEIHLIKYIKNYYDGSIFVDIHPPLGKLIYFYITKLFSFDKDFQIDIIGDLYPEDFPYLWLRLFSGICGIGHVLLTFFTLRITCNSVISIVITILICLENSMVTVSRLILLEGPSLFVQSLVIYNYKAFTTRIPFTGCWYFNLFVTGIALGLNISLKISGLFTFAWVGILTCVQLWEILGDLRISIWQFIKHLVLRVVAFIMVPLTIYCSVFYIHFENLPNEGPGSGFLTPHFRSTLDDYQQQPLQVLYGSTITIKHNALEKYLHSHDLTYPRGSNLQQVTLYDFPDVNNEWVIETKQKYNEEKLMTDQREVKDGDVVRLYHKATGHYLHVNDIRPPISEHEYSYEVNGNETRGLLGNEDYEFKIRMLVKKPHAENDLPLIKLRTTETIFQLIHQATRCNLMSHEQKLPDWGEYQNEVLCVKEPTIPNTLWYVESSSHPLLKDTKKLKTFPKFSFWSKLIETHKVMFNLNKGFTNPHPYASKPLDWPLLSRGIAFFSNYNLKSIDEESSLIYYLGNVAIYYSVFFVGLIAIFKCAIYSFIKLNPYASPPSSSKSSPYANFYNNSWPYLVGWFINYIPYCLMSRNLYLHHYLSALNFGILLLSQYLNYRVAKNKIIGGIITATIFVSAIYCFYEFIPITYGLPWTLDQCNSHKWFPNWDIDCMTYTG
What is the function of this protein?
Protein mannosyltransferase (PMT) involved in hyphal morphogenesis and drug sensitivity.  Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.  PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins.  Required for biofilm formation.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 5, Protein mannosyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLO2_AERHH
Sequence: MYPVITVPAFNDNYIWLIRHENHCLVVDPGDAEPVLERLAALDLQLDAILLTHHHHDHVGGVTALLGHFPHARLYGPKLDPMPAHHGQWLDDGDQINWHGLSLEVIHVPGHTHGHIAYYGHGMLFCGDTLFSAGCGRLFEGTPAQMHASLQRLAALPDDTLIYCAHEYTLSNLRFAYAVEPDNHAIQQRIGLISKLRQQGLPSLPSRLGDEREFNVFLRCEQDSVKFSAEKHALKCLENPEDTFTVLRSWKDVF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: BL1S4_LACTC
Sequence: MSAPDSNSGHAHDSAQNEGAAEGTRDPFGIDRLSVDYDYLLYRIQDHVTSIQLSTTEICRQQNQLVEQGIIGDAIDINIEEMRRILQKCEELETHFDMLDQIDSIVQTFRPRLDDIVREHRELTRNTERRI
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit CNL1, BLOC-1 subunit CNL1, CNO-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S4 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Punctate pattern.
Protein: PAN2_CHICK
Sequence: MNFEGLDPSLAEYAPTLHPALDPVLDPHLNPSLLQNVELDPEGVPLEGIAVPESVHIVEGMYSELHTAVSEVGVPVSVSHFDLHEEMLWVGNHGGHATSFFGPTLERYSSFQVNSSDDIRQIQSLESGVLFLTKTNLKCMSRGGLIIFDYLMDEAEDMHSLLLTDSSTLLVGGLQNHVIEIDLNTVQETQKYTVEVPGITIMRQSNRFFFCGHTSGKVSLRDLRTFVVEHEFDAYSGSLSDFDVHGNLLVTCGFSSRMNGLACDRFLKVYDLRMMRATTPLQVHIDPFFLRFIPTYTSRLAIISQTGQCQFCEPTGLANPADIFHVNTVGPLIMTFDVSASKQALAFGDSEGCVHLWADSPEVTFNTYSRETDFALPCIVDTLPHLDWNQDLVPLSLIPVPLTSETLLSDWPAANSAPAPRRAPPVDPEILRTMKKVGFIGYAPNPRTKLRNQIPYRLKEADNEFDSFSQVPESPIGREEEPHLYMVAKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLVQNHLCQKEFCLGCELGLLFHMLDLSRGDPCQGSNFLRAFRTIPEASALGLILADSDEATGKVNLGRLIQSWNRFILTQLHQETQEQEGPQAYRGAGSSTFGSSGDSVIGQLFSCEVENCSMCRCGKETVRVSSTLLFTLSYPESAEKPVKDYEFAQILKRSICLEQNTQAWCENCEKYQPTVQTRNIRCLPDVLVINCEVNSSKEADFWKTQAEYAFQRALMKRGGFEITKGKEISLGDWKELGNPEVGHSYPSVEELKNIWIPHAIKMRLTKNKELDVCNWSESDELSPNDDPESVYVYDLMATVVHILDSRTGGSLVGHIKVGETYHQRKEGVTHQQWYLFNDFLIEPVDKCEAVQFDMSWKVPAILYYARRNLNSKYNLVIKNPIEASVLLAEASLARKQRKCHATFIPLMLSEMPQAGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGVPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDVGVKFVGHGLQKDFRVINLMVPKDQVIDTVYLFHIPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSQGGSEPDDFRKVLKALYEKGRKLDWKVPEPDSQSSPKHGAVFPPVLAL
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, Inactive ubiquitin carboxyl-terminal hydrolase 52, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: ATP95_VIBCE
Sequence: MNEPTRIPKYVKDKIRQAKQGDLYSSFTVSEYYYDGEVLERDIEQSELYLRNVSRIINNAKIRLRNISLYDYKKFSKLKFTSSEKNTTIIIGNNGSGKSTILESISKCLQFLSDNIRIQNNNNYKFQDSEINIHSISGQTIVRCILEIENDFSFSCSLTKNRENISRKVSSELEEFKALARMYQRSNELDNNTLSYPLLAYYPVERSVTLKRDDAVKYYERKKAKYSDKSEGLKNAFDGTSNFNDFFSWYKEIDDIINEFKANDSITKEEIEYLLSKTDNKEKIGSLISQLLEKKNNYNNNEDREFLIRQQKVIQESIKTFVSDIDQVKISRTPHLDMTVIKNGSEISIFNLSQGEKTLIALVSDIARRLVILNPSLENPLNGYGIVLIDEIDLHLHPKWQQTIVQKLENTFPNIQFILSTHSPLVLTTVTSEQIKIINELDYRFKLLSPTSNPFGKNASDALAIMETSESPLVHSEEILALIKKYESLVKRGQEDCRKTKEIKKTHRKHWIYI
What is the function of this protein?
Probable ATPase component of antiviral defense system retron Vc95, composed of a non-coding RNA (ncRNA), a reverse transcriptase (RT), this protein and a putative HNH endonuclease.  Expression of retron Vc95 confers protection against bacteriophages T2, T4 and T6.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T4 but do not collapse, at MOI 2 cultures enter growth stasis.
What are the official names of this protein?
Retron Vc95 probable ATPase, ORF540.
Protein: SPCS3_HUMAN
Sequence: MNTVLSRANSLFAFSLSVMAALTFGCFITTAFKDRSVPVRLHVSRIMLKNVEDFTGPRERSDLGFITFDITADLENIFDWNVKQLFLYLSAEYSTKNNALNQVVLWDKIVLRGDNPKLLLKDMKTKYFFFDDGNGLKGNRNVTLTLSWNVVPNAGILPLVTGSGHVSVPFPDTYEITKSY
What is the function of this protein?
(Microbial infection) Plays an important role in virion production of flaviviruses such as West Nile virus, Japanese enchephalitis virus, Dengue virus type 2 and Yellow Fever virus.
What are the official names of this protein?
Signal peptidase complex subunit 3, Microsomal signal peptidase 22/23 kDa subunit, SPC22/23, SPase 22/23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TX608_LYCSI
Sequence: MKLLLFTALVLVVISLIEVEAENERACIPLEKECTKTPGNCCSGLKCDCYRRFEQGVAKGVQCWCIEKDVTYKGV
What are the official names of this protein?
U6-lycotoxin-Ls1g, Toxin-like structure LSTX-F8.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 06 (U6-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DUT_METFK
Sequence: MSLTIDVKILDNRLHHMLPSYATPGSAGLDLRACTEHTQTLAPGETIMIPTGMAIHLADPHYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLLVSCWNRGKESFILNPLERIAQLVIVPVMQANFNIVDDFQASERGTGGFGSTGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YQGF_PROM1
Sequence: MIQPKPCSVLSLDIGDKRIGIAGCDPLGISITHLPAIFRDSFEKDLKEFEKICFDRRVEGLICGNPLDMNGMETKQSIRCKKYGIKLAKCLKLPLAFINEHCSTLEAKEKFSLKNDKTGRLDSAAAAILLQQWLIEGPDLDDSN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_SHEFN
Sequence: MKTPIELKIIDSRIGNEFPLPAYATPGSAGMDLRAMIDTAMVIEPSQTVLIPTGIAIHVADPSLAAVILPRSGMGHKHGIVLGNLVGLIDSDYQGQLMVSCWNRSDKPFTLEIGDRLAQLMFVPVIQATFAVVDEFNSSDRGEGGFGHSGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: HAP1_YEAS1
Sequence: MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNIPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQNRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHMNQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITSQMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGLVDFYRADFPIWE
What is the function of this protein?
Regulation of oxygen dependent gene expression.  It modulates the expression of Iso-1 (CYP1) and Iso-2 (CYP3) cytochrome c.  In response to heme, promotes transcription of genes encoding functions required for respiration, controlling oxidative damage and repression of anaerobic genes.  Binds to the sequence 5'-CGGNNNTNNCGG-3' (By similarity).
What are the official names of this protein?
Heme-responsive zinc finger transcription factor HAP1, CYP1 activatory protein, Heme activator protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCME_HAEIN
Sequence: MNPRRKSRFKLVIFVVLGIAIASGLMLYALRQNIDLFYTPSEVIQGKDNNPNQKPEVGQRIRVGGMVVEGTVVRDPKSLKVRFDLNDIGPAITVEYEGILPDLFREGQGIVAQGVLTQPTVLTATEVLAKHDENYVPPELGEKMQKVHKPMGIEAADLKGESARDRQEKEGAK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TRUA_GEOUR
Sequence: MRQIKLIIEYDGTNYSGWQVQPNGITIQQLIEASLATMLGEPVKLHSSGRTDAGVHALGMVAAFKTGKLLPLRAFSDGLNALLPNDIAIRDAVEAPLSFNPRADAKSKHYRYTIYNAVRRSPLARLSSWHLRGALDIERMQAAASHFVGEHDFAAFRASNCAAKTTVRRLFSVSVAKDGESVIIDVHGSGFLKNMVRIIAGTLAEVGQGKKNPDAVPGLLVSGDRAASGITAPPQGLCLVEVFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TRPC_BURA4
Sequence: MSDILDRIIAVKREEVAAAMRSAPLEALKLEASARDLRDFVGALRAKQAAGHAAVIAEVKKASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGSVRYLEEARAACTLPVLRKDFIVDAYQILEARAMGADAILLIAAALDTPLMQDLEAYAHSLGLAVLVEVHDRDEMEQALTLKTPLLGINNRNLRTFETSIQTTLDMLDMIPPERMVVTESGILSRTDVDTMRAANVNAFLVGEAFMRADQPGEELARMFF
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: AMPA_MYCSS
Sequence: MSSDPGYQAPVVTVSSSIPRRGVGDSVLIVPVVTRDDAAAVLAAAPFLDKDAVREIEAALKSLGATGGEGQTHRLVVSALPVASVLTIGLGKERDEWPADTVRRVAGNAARSLDKVAAVLTTLSALDLEAAIEGLILGSYRFTEFRSAKTAPKDGGLRAITALSQESKSRARDAAQRATDIATAVATARDFVNTPPSHLYPDEFAKRAKALGEAAGLEVEILDDKALVKAGYGGIVGVGKGSSRPPRLVRLSHKGAVRTRTRGARPGGSKRVALVGKGITFDTGGISIKPAANMHHMTSDMGGAAAVIATVVLAAKQKLPIDVIATVPMAENMPSATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIETSTLTGAQTVALGSRTPGVMGSDAFRDRVATLSQQVGENAWAMPLPEELKDDLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDVAAPAYNSGGPWGYTPKGGTGVPTRTMFAVLEEIAREG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_GEOSL
Sequence: MGFKHKDIIGLQDLTREEIQLLLDTADNMKEINSRDIKKVPTLRGKTVVNVFYEASTRTRTSFEIAAKRLSADTINISASTSSVTKGETLSDTARNILAMKPDIIVMRHAASGAHHYLAQRVSCSVINAGDGAHEHPSQGLLDMLTMRQKFGTIEGLTVAIVGDITHSRVARSDIFGLTKMGAHVRLAGPPTMMPPGIERLGNVTVCRDMREAIEGVDVVMMLRIQLERQGKTLLPTLREYARYYGLNPQNLKLAKPGAMVMHPGPINRGVELSSYVADSDQSAILTQVENGVAVRMAMLYHVSGGELATE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: IXTPA_STRT2
Sequence: MTKSIFEYKDDQDWYLASFGSYNHLTCFGDDEAYEQYVDFFQGLTSTLDVSGFQLHVVKHSSDLRLVSFILDCLKEELGRDLVVTQHQGTLLVSEGDKLLYVHVPREGVSLDDFFGSDNKSDFGDVLLIATRNEGKTKEFRKLFGKLGIKVENLNDYPDLPEVAETGMTFEENARLKAETISKLTGKMVLSDDSGLQVDVLGGLPGVWSARFAGPEATDAENNAKLLHELAMVLDDSKRSAQFHTTLVVAAPGRDSLVVDADWKGYIGREPKGDNGFGYDPLFLVGNTGRTAAELSTEEKNEQSHRGQAVKKLMEVFPAWQNKQ
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: AMDS_ASPOR
Sequence: MPSASWEDLAADKRARLEKSIPDEWKFKSVPIEGSVIDLPEKSGILSPSEIKITNSSATELVAQLANGTLKSVDVTLAFCKRAALAHQLVNCAHDFFPELALAQARELDRYFETHKKPVGPLHGLPISLKDQLRVKGTETCMAYISWLGKRDTSDSILTALLRKAGAVFLVKTSVPQTLMVCETVNNIIGRTSNPRNLNLSCGGSSGGEGAMIAMRGGAIGIGTDIGGSIRVPAAFNSLYGIRPSHGRLPYGGMTNSMEGQETIHSVVGPIAHSAQDVRLFLQSVLKEEPWKYDSKVIPLPWREAEENAAQAKIAEKSLNFAFYDFDGVVRPHPPITRGVEIVRSTLEKDGHTVAPWTPYKHAFAVDLANKIYAADGSTDVYKHINASGEPAIPNIKDLMNPNLPKADLNEVWDAQLQKWRYQCEYLDKWREWEERTGKELDAIIAPVAATAAVRHNQFRYYGYATVFNVLDYTSVVVPVTYADKAVDHRLADYQPVSDMDKAVYAEYDPEVYHGAPVAVQIIGRRLSEERTLAIAEYVGKLLGH
What is the function of this protein?
Allows acetamide to be used as a sole carbon or nitrogen source.
What are the official names of this protein?
Acetamidase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: VKT87_DRYCN
Sequence: MSSGGLLLLLGLLTLWAELTPVSSKDRPDFCHLPHETGPCKAKIQAFYYNPIYDTCLKFIYGGCEGNANNFKTMDECKRTCAE
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 87, SPI-87.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: APAG_ECO8A
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: TEPP_RAT
Sequence: MARIIDLVPWDECSAHLYASPAILIPLERVRRPLAGVKHQLYHPGLPSLRRMDMDSVKGCLSDEHCQSSTYYTKDDFNEAHFTLLGVPNKPLHCLDFTATGQKLCHKYRDGKMIPIVPGIQRADWPCFTRAIEDWSQFVSKSGEFKLPCANRRVEGFSGYAVRYLKPELTQNWRYCLNQNPSLDRYGQKPLPFNTLNSFRRFGSHYSRINYLTPWH
What are the official names of this protein?
Testis, prostate and placenta-expressed protein.
Protein: TWF_DROPS
Sequence: MSHQTGIRANEQLAKVLGKAKNGKLRVVKVSIENEQLSCSATADVKKDWERDYDKLLGPLLEETVPCYILYRLDAKIPLGHSWLLISWIPDTASIRQKMVYASTKATLKTEFGSAYITEELHATTLEETTLEGYRKHKRDFAAPAPLTTREEELKELRKTEVHTEISTNTRHQTLGGISCPLTDATVAAVQDLVRGNYDYLQFRIDLEEERIHVSHAAQVELSALPKQVPEDHARYHLFLFRHTHEGDYQESYVFVYSMPGYTCSVRERMMYSSCKAPFLEQLAALGVDVVKKLEIDNGNELTEAYLLDELHPKKILHRPAFAKPKGPPNRGAKRLTRPSNEDQV
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin (By similarity).
What are the official names of this protein?
Twinfilin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: DXS_PSESM
Sequence: MPTTFKEIPRERPVTPLLDQADTPHGLRRLGEAELETLADELRLELLYSVGQTGGHFGAGLGVIELTIALHYVFDTPDDRLVWDVGHQAYPHKILTGRRARMSTLRQKDGVAAFPRRSESEYDTFGVGHSSTSISAALGMAIASRLQGSERKSIAVIGDGALTAGMAFEALNHAPEVAANMLVILNDNDMSISRNVGGLSNYLAKILSSRTYTSMREGSKKVLSRLPGAWEIARRTEEYAKGMLVPGTLFEELGWNYIGPIDGHDLPTLIATLRNMRDLKGPQFLHVVTKKGKGFAPAEVDPIGYHAITKLEPLNAPVSVQKKVSSPKYSGVFGQWICDMAEADSRLVGITPAMKEGSDLVDFSERFPERYFDVAIAEQHAVTLAAGMACEGSKPVVAIYSTFLQRGYDQLVHDVAVQNLDVLFAIDRAGLVGEDGPTHAGSFDLSYLRCIPGIVVMTPSDENELRKLLSTGYLHTGPAAVRYPRGTGPNAVIEANLDPVEIGKGVVRRQGQGVAILVFGVQLAEALVVAEKLDATVIDMRFVKPLDEALVRETAASHELLVTLEENAVMGGAGAAVSEFLARANILKSVLHLGLPDVYVEHAKPAQMLAECGLDAEGIEAAINERLALIG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PDIA1_RABIT
Sequence: MLRRAVLCLALAVTAGWAWAAEEEDNVLVLKSSNFAEELAAHKHLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSDIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLADSAAAESLVESSEVAVIGFFKDVESDAAKQFLLAAEATDDIPFGLTASSDVFSRYQVHQDGVVLFKKFDEGRNNFEGEVTKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPRSAADHDGKLSGFKQAAEGFKGKILFIFIDSDHADNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEGITEFCQRFLEGKIKPHLMSQELPEDWDRQPVKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKEHQDIVIAKMDSTANEVEAVKVHSFPTLKFFPAGPGRTVIDYNGERTLDGFKKFLESGGQDGAGDEDGLEDLEEAEEPDLEEDDDQKAVRDEL
What is the function of this protein?
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds.  At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell.  May therefore cause structural modifications of exofacial proteins.  Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins.  At high concentrations and following phosphorylation by FAM20C, functions as a chaperone that inhibits aggregation of misfolded proteins.  At low concentrations, facilitates aggregation (anti-chaperone activity).  May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis.  Also acts as a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.  Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
What are the official names of this protein?
Protein disulfide-isomerase, PDI, Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein. Note=Highly abundant. In some cell types, seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources. Localizes near CD4-enriched regions on lymphoid cell surfaces. Colocalizes with MTTP in the endoplasmic reticulum.
Protein: GUN1_PERAE
Sequence: MDCSSPLSLFHLLLVCTVMVKCCSASDLHYSDALEKSILFFEGQRSGKLPTNQRLTWRGDSGLSDGSSYHVDLVGGYYDAGDNLKFGLPMAFTTTMLAWGIIEFGCLMPEQVENARAALRWSTDYLLKASTATSNSLYVQVGEPNADHRCWERPEDMDTPRNVYKVSTQNPGSDVAAETAAALAAASIVFGDSDSSYSTKLLHTAVKVFEFADQYRGSYSDSLGSVVCPFYCSYSGYNDELLWGASWLHRASQNASYMTYIQSNGHTLGADDDDYSFSWDDKRVGTKVLLSKGFLQDRIEELQLYKVHTDNYICSLIPGTSSFQAQYTPGGLLYKGSASNLQYVTSTAFLLLTYANYLNSSGGHASCGTTTVTAKNLISLAKKQVDYILGQNPAKMSYMVGFGERYPQHVHHRGSSLPSVQVHPNSIPCNAGFQYLYSSPPNPNILVGAILGGPDNRDSFSDDRNNYQQSEPATYINAPLVGALAFFAANPVTE
What is the function of this protein?
Involved in ripening fruit process.
What are the official names of this protein?
Endoglucanase 1, Abscission cellulase 1, Endo-1,4-beta-glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
Protein: RR11_EMIHU
Sequence: MIKQVKRFTSKKSKKTVNAGIVHIKSTFNNTIVNITDKQGNTLFWASAGGCGFKGAKKSTPFAAQSAAEKVGSMAVEQGMKQAEVIISGPGNGRETAIRALQSCGLEVLLIKDITPVPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.