PharMolix/UniProtQA huggingface dataset:
Protein: RRF_SHESM
Sequence: MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIEDARTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAEAEGGRVAIRNVRRDAISDVKKLEKAKECTEDDVRRFEDEVQKFTDAHIKKVDEILAAKEIELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU71A_PENRW
Sequence: MIWKSLFSALAILTHILPALTAPALDSELSSQSEDKYVFAHFMVGIVKDYQLEDWKEDMTTAQSIGIDAFALNCASIDSYTPTQLALAYEAAEQVNFKVVISFDFAYWTNGDTEKITEYMKQYAGHPAQMQYKGAAVVSTFVGDSFNWDAVKQNTPHPIYAVPNLQDPAEATTGPAKSADGAFSWLAWPTDGGNSIIPGPMTTVWDDRFVHFLAGKTYMAPVSPWFSTHFNTKNWVFVCENLPTLRWEQMLSLQPDLIEIISWNDYGESHYIGPYSAHHSDDGSSQWATNMPHDGWRNLFKPYIAAYKSGAKTPTVEADEVVYWYRPTPKGVVCTGDTLSAPMGADMLSDSIFVATMLTSPGTLTVQSGNNAPVDIEVPAGIVTSNVTMGVGAQSFKVARDGQTILSGQGGLDVKDSCVHYNFNVYVGSTKGGDGSNTTGARGSM
What is the function of this protein?
Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides.  May enhance the efficacy of fungal antibiotics by degrading bacterial exopolysaccharides.
What are the official names of this protein?
Mutanase Pc12g07500, Endo-1,3-alpha-glucanase Pc12g07500, Glucan endo-1,3-alpha-glucosidas Pc12g07500.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 71 family.
Protein: KPL_ARATH
Sequence: MEPNNVERNLQSLRRLYSLLVANARNEYIPEAYKLDDNTQFLLKRLLDFASHEHFVTQSNLLATQLRVFPKTVLHGAKPSNVADSSETTPPAMLSQINGSHITRVSKPLEAKGTLQRDLRVDQIRSNPSKDVLTEEVVDAIEQIDTQLSALSFVSSRVDSDERTRSVKSFVTPPTEECRQNSQASMPCLRSNYMTVSQKSVISGAEVTFPYNDQLVRVTSPPQPLPPRAVSGFKKPNQSNRASQKMPIMKPTLMDQETETFDDDSSETEADQTPSATGSESEDEEVSTSQEYSGETGSSSGSEWETQAENDTESKSESSYPPQNDDSVSEVSTSPPHTDRDTSREPGKQRRNVMGRFKRIKNKIGQIFHHHHHHHHHHHHHDKEKPSAWNKLQSKFHHKHQEKSKERKRPMSESKGLTTHKQQHQGGHFHALVEGLVRHRKHSKKQKHQLKSDAKKTEWWKLLKKRQGGGVKIPKRGRVKLGKKKHYLSKNV
What is the function of this protein?
Regulates positively reproductive function by facilitating male gametophyte formation and double fertilization.
What are the official names of this protein?
Protein KOKOPELLI.
Protein: TBA1A_RAT
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1A chain, Alpha-tubulin 1, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: APAG_ECOSM
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: NUPR2_MOUSE
Sequence: MDPPTRPSVSGPRTRARPPPPEALPTVGFEEEVYDCLDYYYLRDFPASGAGRSKGRTRREQQLRTNYPVPGGHERKVAQILLNGQRKRRQRQLQPRPRTRLA
What is the function of this protein?
Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells.  Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation of pancreatic cancer cells.  Plays a role as a negative regulator of the protumoral factor NUPR1.
What are the official names of this protein?
Nuclear protein 2, Nuclear transcriptional regulator 1-like protein, Nuclear transcriptional regulator protein 2.
What is the protein family that this protein belongs to?
Belongs to the NUPR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGT_VIBC3
Sequence: MPQGYLQFPNIDPVLFSIGPLAVRWYGLMYLVGFLFAMWLANRRADRAGSGWTREQVSDLLFAGFLGVVIGGRVGYVIFYNFDLFLADPLYLFKVWTGGMSFHGGLLGVITAMFWYARKNQRTFFGVADFVAPLVPFGLGMGRIGNFMNSELWGRVTDVPWAFVFPNGGPLPRHPSQLYEFALEGVVLFFILNWFIGKPRPLGSVSGLFLAGYGTFRFLVEYVREPDAQLGLFGGFISMGQILSLPMVIIGILMMVWSYKRGLYQDRVAAK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1170_METJA
Sequence: MILMITSTTDNLEGFKIVKYLGVVIGYGDDPDDALEDLIDVAEDMGANAVIGIRISNELTTEIISDENYAVPELTYYAYGTAVIVEKID
What are the official names of this protein?
UPF0145 protein MJ1170.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family. Highly divergent.
Protein: ISCR_SALHS
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASGRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: DCUP_PROM9
Sequence: MGENLPLLLSAALGKKVTRPPVWMMRQAGRYMKIYRDLRERYPSFRERSENPELSYEISMQPFHAFKPDGVILFSDILTPLPGMGINFEIIESKGPIIEDPIRTLSQIESLKELNPSESLSFVGQVLSSLKKDVNNEATVLGFVGAPWTLAAYVVEGKSSKNYSLIKSMAFKEPDLLHKLLDHFAKSIGEYLKFQIKSGAQVVQIFDSWAGQLSPQDYDIFAGPYQKKVVDIVKEEYPDTPVILYISGSAGVIERMAKTGVDIISLDWTVDIEEACKRIPDEIGIQGNVDPGILFGNKESIKERIDDTFNKIKDRKYILNLGHGILPGTPEENAQTFFEHGKKLTY
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSCL4_ARATH
Sequence: MATLTDIGVAATINILTAFAFFIAFAILRLQPVNDRVYFPKWYLKGLRSSPIKTGGFASKFVNLDFRSYIRFLNWMPQALRMPEPELIDHAGLDSVVYLRIYLLGLKIFFPIACIAFTVMVPVNWTNSTLDQLKNLTFSDIDKLSISNIPTGSSRFWVHLCMAYVITFWTCFVLQREYKHIASMRLQFLASEHRRPDQFTVLVRNIPPDPDESVSELVEHFFKVNHPDYYLTYQAVYNANKLSELVQKRMKLQNWLDYYQNKHSRNPSKRPLIKIGFLGCWGEEVDAIDHYIEKIEGLTRKISEEKETVMSSTKSLVPAAFVSFKKRWGAVVCSQTQQSRNPTEWLTEWAPEPRDIYWDNLALPYVQLTIRRLVIAVAFFFLTFFFMIPIAFVQTLANIEGIEKAVPFLKPLIEVKTVKSFIQGFLPGIALKIFLIVLPSILMLMSKFEGFISKSSLERRCASRYYMFQFINVFLCSIIAGTALQQLDSFLNQSATEIPKTIGVSIPMKATFFITYIMVDGWAGVAGEILRLKPLIIYHLKNFFLVKTEKDREEAMDPGTIGFNTGEPQIQLYFILGLVYAAVSPILLPFILVFFALAYVVYRHQIINVYNQEYESAAAFWPDVHRRVVIALIVSQLLLMGLLSTKKAARSTPLLFILPVLTIGFHKFCQGRYQPIFVTYPLQDAMVKDTLERMREPNLNLKTFLQNAYAHPVFKAADNLANEMVVEEPAPDKTPDLVATKRGSRRFNSGSAETFT
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
CSC1-like protein At3g21620.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UPPP_PROM5
Sequence: MDFLKFIFYGIIQGLTEFIPVSSTAHLKIISQLFGVKDPGSSLSAIIQIGSVLAIFWYFRKYIFNTINSNSKILRPSFFSNKIYKSIFIGTIPIVLIGGIVKLFVTDFSNSFFRSNFSIAVVSILMSLIMFLADISTNKFINLSNHKYRNSLFIGISQAFAIIPGVSRSGATISMALLSGWDRKDAAKFSFLLGIPSISLAAFVEFITSINEFSTFPFLPLFVGLITTFFSSLLAIDFLLKYVSSNGLKIFIYYRLVFGILIILNL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_ENDTX
Sequence: MVKINFQIKKKKSNGPNFIGFDAVRVSVASPDQIKTWSYGEVKKPETINYRTFKPERDGLFCNRIFGPTKDWECHCGKYKYIKYKGTICDRCGVEVTESKVRRERFGHINLAVPVAHLWFLKKPPSRVGILLNMKISDLEKVIYYAKYIVMGDLKDRSGISFFARKGMLMGGEDFNLFKYGINNPIVKEEFKNIFDGIVCEEIKLDSNLTKALKQLKVLVKGQADSAGISTEEAAKKILENVKKGDIYYKVYFKPHSVYYYIDLDPSSHGEIKKILSEKFEKSSTVSITETDKKIRIEFFDIEKDKIYNDLRKDSFALKKYEGCLRIEILKNKIPFIENFSRSDSFVLLEESDINNIQNGFGDSLKVNIGAEAVRSLLEEINLDDEMKNIYAEIKKTKSDAERARLLRKLRVVEGFLNSQTRPEWMILTVLPVIPPDLRPLVALDGGRFATSDLNDLYRRIINRNNRLRHIEQLKAPIVMINNEKRLLQEAVDALIDNDSRMRPVTGAGNRILKSLSDTLKGKRGRFRQNLLGKRVDYSGRSVIVVGPNLRLNQCGIPKEMALELFKPFIVKELIKQENITLRSAKRMLERGDLKVWNILEKVTQSHPVLLNRAPTLHRLGIQAFEPVLVEGKSIQLHPLTCSAFNADFDGDQMAVHLPISLEAQLEARVLMMATRNILSPASGRPIAVPSQDMVLGNCYLTKEKYGVVGEGKVFSSVSEAISAYQAEKVDLQARIKVAGITSIRDKNLNNDDEQPDVTKWKNCKSEDDTEIINYTTVGRIIFNEQLPKNDDGSYALEYQNKSMTKKELVALVDRCYKELGQFKTTVLLDEIKRIGYKYATLAGISISIDEMKVPTEKEKMVREAKTKISEIEKQAKLGLITESERYNRIIDIWTRVTDEISDIMFDEMRKEETKAYKPGQNRFNSIFMMADSGSRGSRQQVRQLAGMRGLMAKPQKKLTGGIGEIIETPIISNFREGLTVLEYFISTHGGRKGLADTALKTAEAGYLTRRLVDVAHDVVVREEDCGTVNGVFIGTLRCGDEIIEKIDERVVGRTALDNVVDIVHDDLIIKRGELITPKKAEKLVEAGIDKIGIRSVLTCESGHGVCAKCYGVNPATGEQVEMGEAVGILAAQSIGEPGTQLTLRTFHIGGAASRVVQRSEVYAENNGTVNYYNLKTIQNKDGETIVLSRNAELVYTEYPVYRKQIYQIPYGAVIKIYDGQTVEIRVNPITGMKKDILIAKWDPHSKPIISEFDGTVNFVDVKDGVTLQREKSKITGQIERVIIEHSSDRRSPRIVVKKDDGSVVEYPLPVDTTLVVRDKDRVKSGDILAKIPQEISRTKDITGGLPRVAELFEGRRPRNVAVVSEIDGIVHLVGPTVKGNVKVEVENPETKMKKSYLVRAGRHLVVYEGDRVKEGEALSDGAINPHDILKVKGPKEVQEYLVNEIQQVYRLQGVSINDKHIEIIVRQMLSNVRITDSGDSHYLNGEIVSRYKYEIDRKAIKGKKGKAPIAHSILLGITKASLSSDSFISAASFQETTRILTEAAVSGQVDYLKGLKENVSIGRLIPAGTGLAAVDIDDNNKFYSREQNDAND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CU67B_LOCMI
Sequence: GYLGGYAAPAISYAAPAVSYAAPAVAYAAPAAVAPAALTSQSSNILRSYGNLGQVSTYTKTVDTPYSSVTKSDVRVSNDAIAHVAAPALAYAAPAAYAAPAYYH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 67, isoform B, LM-ACP 67B, LM-67B.
Protein: SSG1_MANES
Sequence: MATVIAAHFVSRSSHLSIHALETKANNLSHTGPWTQTITPNGLRSLNTMDKLQMKTQSKAVKKVSATGNGRPAAKIICGHGMNLIFVGAEVGPWSKTGGLGDVLGGLPPAMAARGHRVMTVSPRYDQYKDAWDTSVSVEIKIGDRIETVRFFHSYKRGVDRVFVDHPMFLEKVWGKTGSKIYGPRAGLDYQDNQLRFSLLCLAALEAPRVLNLNSSKNFSGPYGEEVAFIANDWHTALLPCYLKAIYQPMGIYKHAKVAFCIHNIAYQGRFAFSDFPRLNLPDKFKSSFDFIDGYEKPVKGRKINWMKAGILESDRVLTVSPYYAQEVISGVERGVELDNFIRKTGIAGIINGMDVQEWNPVTDKYIDIHYDATTVMDAKPLLKEALQAEVGLPVDRNVPLIGFIGRLEEQKGSDIFVAAISQLVEHNVQIVILGTGKKKFEKQIEHLEVLYPDKARGVAKFNVPLAHMITAGADFMLVPSRFEPCGLIQLHAMRYGTVPIVASTGGLVDTVKEGYTGFQMGALHVECDKIDSADVAAIVKTVARALGTYATAALREMILNCMAQDLSWKGPARMWEKMLLDLEVTGSEPGTEGEEIAPLAKENVPTP
What is the function of this protein?
Responsible for the synthesis of amylose in reserve starch.
What are the official names of this protein?
Granule-bound starch synthase 1, chloroplastic/amyloplastic, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule-bound.
Protein: PUR9_ACIF5
Sequence: MGEITRALISVSDKRGVVEFARRLQDFGVEILSTGGTAKALMADGVAVQEVGDYTGFPELLEGRLKTLHPKIHGGLLAKRDDSSHTRQMAEYGIPAIDLLCVNLYPFAETIASADCTLEEAMENIDIGGPTMLRAAAKNWEGVTVLVDPDDYAAVLQEMEQSYGGVGASTRFRLATKVFAHTARYDGAIANYLSSLGPDGNRTTFPQTLSLQFKKAQDLRYGENPHQAAAFYRDGSGGGLADAHQLQGKELSYNNIGDGDAAVALVMEFAEPACCVVKHGNPCGVAVGPDLLGAYQRAWAGDPISAFGGIVACNRPLDAQTAELISDQFIEMVLAPAILPDARPILAKRKNLRVLAFDDGRAWRRTGWDYKRVRGGLLVQNFDQAMEAETDWKVVSERAPTVQEARDLAFVWRVGKYVRSNAIVYGREGQTVGIGAGQMSRVDAARCGVAKALELGFDLHGAALASDAFFPFRDGIDAAAAAGVKAIIQPGGSIRDEEVIASANEHGIAMVFTGVRHFRHG
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DU4L2_HUMAN
Sequence: MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPLLETEAPGELEASEEAASLEAPLSEEEYRALLEEL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Double homeobox protein 4-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: XB36_ORYSJ
Sequence: MGNSLGCVGLGERLAAAAKDGDAAEAQRLLAANPGLARCTTFGNLNSPLHVAAAKGHHEIAALLLENGADVNARNIYGQTPLMQACRFGHWEVVQTLLVFRCNVWRVENLSGRTALHMAAAGGHVKCVRLLVADAAGDRDGYVNKAANGGVTALHLAALHGHVECVHLLIDERASLAAQTLPCAAPPMASIGAGSTPLHYAACGGEVKCCQILVSRGADRTAINCNGWLPIDAARIWGCNWLEHVLSPKSHLPIPKFPPSGYLSQPLPSLIAIAREQGLNLSSEVSDGFDEGADACAVCLERPCTVAAEGCDHELCVKCAMDLCSVIKSYDSAGIAGEIPCPLCRTGIASFRTTAAPPPPSLAGSPARRSRRNNSGGGGGEHEASNSGGSEKGYGSIDPDAGAVVPLYYAPPFAPSAILT
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase XBOS36, Ankyrin repeat domain and RING finger-containing protein XBOS36, RING-type E3 ubiquitin transferase XBOS36, XB3 protein homolog 6.
Protein: RS17_COLP3
Sequence: MSETKIRTLQGVVVSNKMDKSIVVLIERRVKHPMYGKYMTRSTKLKAHDETNVCNEGDLVTITEVAPISKSKNWKLVDVITKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: POTA_DESVH
Sequence: MAEKDNIIELRGVTKNFEDTCALDNIDLEIRNGEFLTLLGPSGCGKTTILRLISGFEKPDAGVITLKGQRMDDAPPEARQVNTVFQNYALFPHMSVRENVGFGLRMQRRPKDEIARRVHDALRMVHLEAHADRRPRQLSGGQQQRVAIARAVVNNPLVLLLDEPFSALDYKLRKQMQLEIKHLQRQLGITFVFVTHDQEEAFAMSDRVVVMNDGKIEQIGSPQEIYEEPANLYVARFVGEINILNAVIAANHGDGLYDAVIEGVTFPIRSQRTFAPGDKVNVLLRPEDLRVYTLTEDRPAGPHLTGRIEESVYKGATVDLIVTLSDGRRLMAAEFFNEDDVDINYNPGETVTVSWVDGWEVVLPDGEA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PKS31_DICDI
Sequence: MTQNIDNNNNKLIRDRNDDDDVDRNDDGDVAVIGIGLRFPSGNLKESISKPNQLFNELLNGLDGIVSTSERWSDNYYLNGEIVSKFAGLLPLDEWKQFDPIFFAINQTYDNVSSIDPQQRLLLKCVWEALEDSGIDPISLRGTNTSTFIGNSTIDYYNLQRSPSETQNNIFGSSTHSIANRIGYCFDFRGENLTIDTACSSSSNAINCGYNSIKTNRSNVSIVGGVNIILDPHISKSFTQLDMLSPTGKCHTFSSDADGFVRSEGVGIVVLKKLKDAIKDSNNIYCVIKGSSSNIDGNFDKLNFYSPSKSSQCENIKLAIKSTNGQINESDIDYCETHGTGTPTGDPIELEGISRVFNSAKIPSTTINNNKQVLVGSIKSNIGHLEACSGVASLIKCCLMFKNKLFLQNINFKEPNPLINFKEWGLKVVTEPIKFNENKSTVMLVNNFGITGSNVCLILSELKKNHHNRYENEYHKIEIDSKVNEKKKYLIPLSSNSSTSLNNYKSSIIKLSNSNSSPTTTTSFKELVHNQIKFKSTSLIQKSVIIASDWNEFQDENNQIKLENSDNLISNITVEKKKSPITVMVLCGQGSQYNKMALSLYDNEPIFRESVNRFDKELFKYYGYSVLDKLRSIDDKDLISIHQPILAQPANVIIQVSLYELYKHWGVSADIIIGHSLGEVSSPYCSGMIDFQTLCYLIYHRSVAQNRTTGTGRMLSVNISSDEFINNYQSTTKYESLEIACYNSPTSIVIAGREDLLNEITNEFKSNNIFCTMLGLLSSFHTSSQQMIKDEVCSLNISSKQPSIAVFSTVTTNLFNHQSLPFNADYAFENIRQPVRFTQTITNLYKHIESNDMGNEITFIEVSPHPTLQYYLNQMKSTQSSYFNNGKNITIYSPLNKKKNDYNEFLKTISLLYVNNNFDINFKSQLINDNNNISNTTKLNNLPLYQWDDKEYFKIASFHEKIKSEGPSIHSLGNNTDSPYPSYQTFIDIKKSPFQWLKGHQVSDKFYYPGMGYVHNLLSIYPNQDITISSLEFKSPLVLTEGNNQCLQTTIAPLSKNEFNIKSHYKDQKTNQWILSSLGNFNLTKHNSIISNKLINIQSLKDKCNFTSISKQDFYETIRIKTNLTYKGLFQGVKQCYIGNNCSLSIVSLNEIYNQKEYNHLINNSNMNKFLNTAILDTCLHGSLVAVTQPVVLDRIEGFKYYFSNIPSLNENNNNDDIKELYVFSDIKPRTNYQTYSISVKIILPNGTLLVDISNVVCALVSLGSNPDSTIICKPPLNDIYTPYLQSKDSVVNKPEQFKHLYSVDEFSVNEEDNQFISNELLLSLFYKHINNRCPSINLESLTTLEYNQFKQLYYNSLVNENLFKFIFENLKRYSNILNHDNNQSNIKPKIEKIFIRTTKIMAKQLFPLKDDDSITDTPQSLFESGFLDDFYKNSRVVQPLNNLLSEIIVETLKPILNEPIVFRILEAGGGTGSLSLLILEKICKLLNDNSTTSIINIEFTWSDVSASFFAEIKEKFSSFTNHNNLNIIYRVLDLEKPLLDQDLKASYYDFVVMSNVMHVVKKLKPTLNEIHNILTPNGQLLYIEPPYKSFYFDSIFGCFSQWWPSSDGDIELRPDRCCMKQEKWVNLLSQCNYRDTIMSGNDNLLFLIQTRKPTINEIISEQSISLDQLNSFNNIILFSNNKNRNSCSSSILDLIRLNQELKHKIININNYNEFQSWITNNQNKDNCNKSLIIFLKSIESTMNTSNFKEITFEYIQINQLILKLELSNNFKHLLLSLNSTTDNYLSSSIIGAARYFVEFPQLDLYILNYDNVSIENNQQLSLINYLINPNNNIQKEFTINNNKVYYERYCRRSNNIKSKFQSESFETNKDNLYIQLNSNIEYQLYSKKDELNSNEVEIEVKATGINYKDYLMYIGMIGSDLDIKYGKEIEYGIGIDNPKIGNDFSGIITRLGSNVKKFKVGDQVCGFGSKTNSSHVIIDFNSIYYKPLNCSHSVSASIPSIYITTLHSIYSIGNLKSNESILIHSAAGGIGISSLDLLKSKQHQGYIFLTVGSKDKEEYLINKYGSLITAIYSSRNKDYVYEIKNKLIELGVVEQHQQGVDLILNTLSSEYMDSNFQCLNLSGRIVDLSITHLTPNDYMTNNHYKFNMNYGNVDIEDFPSKLIKRYLKKIIKMINSNKLELSVPIIEYSNNQFKDAIEYINQRKHIGKIIVNHNQDEFNRVYNNYQSNNNQIIMKHSYDISKLNIGKNILLTGQTGIVLEILKYLIKYSNHSIENIIILSKSKLKWELKLLINQSKFKKDNNIKFHFNQIDIEDSNKVNQVLNQLELNENITNIDSIIHFAFMIDIGDVQQVDMNRLNNAHGAKTIGAINLHNQSINRSWNIKQFIMASSVVSIFGSDQQCCYVSACSVIDSLSKYRHSIGLPSLAINLGAISSTGFVSRNNAIETMFKSSIVNLFSPQLVISSLDLFIQNQHQYPNYCLSDFNFEVLTPTLTNQYHSKFDYQINIVKKSNRIKSFSSGNSGANNEIIHSTILNKISELLSIDESKINEDLQLSQYGMDSLVIVQLKNFIDNQLGHNIITIQQLQNNKINQSIEIIKSAKNNNKNNNNNNNKNNSNNKNKNN
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 31, dipks31.
Protein: GPX4_HYLLA
Sequence: MSLGRLCRLLMPALLCGALAAPGLAGTMCASRDDWRCAGSMHEFSAKVLDGHTVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRFLAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLFDKNGCVVKRYGPMEEPLVLEKDLPHYF
What is the function of this protein?
Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity).  Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (By similarity).  Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity).  Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (By similarity).  The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity).  The presence of Sec at the active site is also essential for the survival of a specific type of parvalbumin-positive interneurons, thereby preventing against fatal epileptic seizures (By similarity).  May be required to protect cells from the toxicity of ingested lipid hydroperoxides (By similarity).  Required for normal sperm development and male fertility (By similarity).  Essential for maturation and survival of photoreceptor cells (By similarity).  Plays a role in a primary T-cell response to viral and parasitic infection by protecting T-cells from ferroptosis and by supporting T-cell expansion (By similarity).  Plays a role of glutathione peroxidase in platelets in the arachidonic acid metabolism (By similarity).  Reduces hydroperoxy ester lipids formed by a 15-lipoxygenase that may play a role as down-regulator of the cellular 15-lipoxygenase pathway (By similarity).
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm.
Protein: MIAB_NOVAD
Sequence: MSSSAPSSASPKTFRVKSFGCQMNVYDGERMAELLAAQGMSAAGDGDDADLVVLNTCHIREKATEKVYSDIGRLRRADGSAPLIAVAGCVAQAEGEEIMARAPSVKVVVGPQSYHRLPEMVADAAAGKRSTETDMPAEAKFAALPKRRKSAPTAFLTVQEGCDKFCTYCVVPYTRGAEISRPFSDLVEEAKLLVAGGAREITLLGQNVNAWAGEDDKGRPIGLDGLARALAAEPDLKRIRYTTSHPNDMTDGLIAAHGELEKLMPFLHLPVQAGNDRVLKAMNRSHTADSYMALLERIRAARPDIALSGDFIVGFPGETDAEFEDTLRLVDAVGYAQAFSFKYSARPGTPAATMENHVPVAVMDERLQRLQAALNRDQLAFNKASVGKTCEVLVERRGKHPGQWLGKSPWLQSVHFSGEAEIGDMVTVELIEAGPNSISGRLA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA120_YEAST
Sequence: MRIFSGDNKVVDSLASNPGLMSPSNFGGDFGSRLKVNVTSKKKLNDSSPTSPMESSPVSPELVPILTLLNAHTHRRYHEGVFLILQDLNNNGTHAARKWKDVYGVLLGTQLALWDAKELAEFTDPSCPVSEKKLKEVASKPTYINLTDATLRTLDNSDNIVMECGKNLTNALVVSTTLKNRYFLQFGNKESFNAWNSAIRLCLYECSSLQEAYTGAFISSRGAKLGDIRILLTNRKYDYKDWVSVRFGAGMPWKRCYAVISQSSSKKKGHFGEINLYENDKKVKKNHAMATIVEAKALYAVYPSSPKLIDSSTIIKVVGSVKFEKKESAQEKDVFIMPEKHQAVPSYDTIIRFLIPAMDTFKLYGRPEKLLSSKNDPHSLLFGLPVLPHIYYLEVEDLLPLTNSVSSLHWSNNEWKEHISDILQRKIAQGYCGCNSTSNITSPLPSPFLGSADLFERADGVLSPKLSYGSKSSSNNSSKNSLPKRERVKLSSSSEQDLNNSDSPSIKRKSPPLVISESPHKVHTPTDASFRTRVTEGSPYAKQRHPKPFASSVNDSPSDRAKSRTVPYNNNDRKATTPEKFERGETSCGKNVDESLEKVRNMKLEIPESNFDKFMTDKNLLSVDSKCSNEKKLSVESDLSAIYEKYSNGPFGHTEGLNGSSDETYLRFQRASVHSESNYNSRKSFTPSDFSNGNEEEHAVLQELNSLTQRINELGMESINSNSDSDRINGSYSQVDFGNNNDEDDMNLFDPDFMAQDQLRAEERDYNKDDRTPLAKVPAAFQSTGLGITPDDDIERQYITEHRSRHEVPKRSPEKPSNPLEIGNPYAKPGTRLNTTHTHSKTDRSITPQRGQPVPSGQQISSYVQPANINSPNKMYGANNSAMGSPRNPKTRAPPGPYNQGWNNRPSPSNIYQRPHPSDTQPQAYHLPGNPYSTGNRPNMQAQYHPQQVPMPILQQPNRPYQPYAMNTHMGSPGGYAGAAPPFQPANVNYNTRPQQPWPTPNSPSAHYRPPPNLNQPQNGSAGYYRPPAPQLQNSQARPQKKDGFSQFMPSATTKNPYAQ
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery.
What are the official names of this protein?
CCR4-NOT transcriptional complex subunit CAF120, 120 kDa CCR4-associated factor.
What is the protein family that this protein belongs to?
Belongs to the CAF120 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Bud neck.