PharMolix/UniProtQA huggingface dataset:
Protein: CH10_ECOUT
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: TATA_KORVE
Sequence: MFGELGVPEVLFILGIALLIFGPKKLGDLGKGLGEGVRGFKSALRDEPKKEETKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRUD_IDILO
Sequence: MLAPSQVSLADLPRLHKGDRPQAEFKQTPEDFQVIEQLDVIDDGEGEHQWLWVRKTGANTNFCAEKIARFAGVSERNVSYSGLKDRQAVTWQWFSIQLPGKETLNWNELNDEEMSVERIIRRTKKLKTGFHRANRFVIRLANVSSREALENLWQGVSEQGVINYFGEQRFGRSGDNVAQAERWLMASRPPRISRSKRSLYLSALRSYLFNEIVAERIRQFGIEGTLTGDCVMLEGSQSVFTVEQWDDELKQRLANNNIYLTAPLAGSTNKPLVKGEADAFEQSLLQPFDSWLQALRKLRVEAARRTILLRVENPEISWQGKDAELRFTLPSGAYATTVLNEIVDLSGESR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: PTPA1_CRYNJ
Sequence: MQPHTQPPQPEASSSRAVHIPSDPAPPRPCLTNDAIVSRWQSSPGFQYFWAWIKRRCDRLKGKEIIRGPFDHSAHGIRSLMNMLDQMTSWVEDATPQPQSNQRFGNLAFRTYNKLLQERLPPLIDSWDIPSNLRSQLLPLFINSHAFGHPTRLDYGTGHELAFVLGLWCCVVPGWVGGDNGTEEEEDELILRVFTRYLELTTFLQKTYNLEPAGSHGVWGLDDYCFLPYLFGSAQLLGSNLTPSASLSLALSHHPSATSPPSAPITDLYTLSLHHLTLFKFGASFSEHSPLLYSLSQMPNWVKPHGGLKKMFLGEVVGKRVVVQGIWVGGWCWGEDVPNVEERGDKNEGKGTDAGTKAPWAR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPL_SYNS3
Sequence: MDSITSAASVVAAGLAVGLAAIGPGIGQGSASQGAVEGIARQPEAEGKIRGTLLLSLAFMESLTIYGLVVALVLLFANPFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CNSM_PENEN
Sequence: MVSETVEANGPLYPDYLPFYDPLEKVEMVGPFEHDDPGHRADPSFPNLLEKATNVLELSPHCGTELQGVQISELSTQGLDELALMVAERGCLVFRDQDFTNLGFEKQKEIASHFGPLHKHGWMPHPKNGPEEFVIVYDSKDDLRIRKSWARKSPIQFHVDQSPESQPPGATFFCMLESPPGAGGDTVISNMARAFDRLSPSFRKRLEGLKAVHTTANPIMREIRDNGPDSVLRRPITRTIHPVVVVHPVTKRKALFVNSSYTQSIVGWDEEESDYMLKFLFDHINRGHDFCCRVRYEPGTVVIWDQRVTQHSQTLDYSAGSRRHAFRLTPLANVPIPSLIEEDDGECAKDEGRMLLNLC
What is the function of this protein?
Alpha-ketoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals (PubMed:25571861).  Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan (PubMed:25571861).  The L-tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probably aided by the catalase cnsD (PubMed:25571861).  The cytochrome P450 monooxygenase cnsC catalyzes the heterodimeric coupling between the two different indole moieties, tryptamine and aurantioclavine, to construct vicinal quaternary stereocenters and yield the heptacyclic communesin scaffold (PubMed:26963294).  The O-methyltransferase cnsE then methylates the communesin scaffold to produce communesin K, the simplest characterized communesin that contains the heptacyclic core (PubMed:25571861).  The dioxygenase cnsJ converts communesin K into communesin I (PubMed:25571861).  Acylation to introduce the hexadienyl group at position N16 of communesin I by the acyltransferase cnsK leads to the production of communesin B.  The hexadienyl group is produced by the highly reducing polyketide synthase cnsI, before being hydrolytically removed from cnsI by the serine hydrolase cnsH, converted into hexadienyl-CoA by the CoA ligase cnsG, and then transferred to communesin I by cnsK (PubMed:25571861).  Surprisingly, cnsK may also be a promiscuous acyltransferase that can tolerate a range of acyl groups, including acetyl-, propionyl-, and butyryl-CoA, which lead to communesins A, G and H respectively (PubMed:25571861).  The roles of the alpha-ketoglutarate-dependent dioxygenases cnsM and cnsP have still to be determined (PubMed:25571861).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase cnsM, Communesin biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: ISPD_CITK8
Sequence: MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDSRFAELPLAQHPQVTVVDGGDERADSVLAGLRAAGDAQWVLVHDAARPCLHQDDLARLLSLSETSRTGGILAAPVRDTMKRAEPGKAAIAHTVERTDLWHALTPQFFPRELLHDCLSRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RL33_OPITP
Sequence: MQELVTLECTEARKEGKPVSRYLTTRNKKTVTERIEKKKYNPHLKRHTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CHSTC_HUMAN
Sequence: MTKARLFRLWLVLGSVFMILLIIVYWDSAGAAHFYLHTSFSRPHTGPPLPTPGPDRDRELTADSDVDEFLDKFLSAGVKQSDLPRKETEQPPAPGSMEESVRGYDWSPRDARRSPDQGRQQAERRSVLRGFCANSSLAFPTKERAFDDIPNSELSHLIVDDRHGAIYCYVPKVACTNWKRVMIVLSGSLLHRGAPYRDPLRIPREHVHNASAHLTFNKFWRRYGKLSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASAREAFRAGLKVSFANFIQYLLDPHTEKLAPFNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLQLLQVDRQLRFPPSYRNRTASSWEEDWFAKIPLAWRQQLYKLYEADFVLFGYPKPENLLRD
What is the function of this protein?
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate.  Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.  Activity toward partially desulfated dermatan sulfate is however lower.  Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
What are the official names of this protein?
Carbohydrate sulfotransferase 12, Chondroitin 4-O-sulfotransferase 2, Chondroitin 4-sulfotransferase 2, C4ST-2, C4ST2, Sulfotransferase Hlo.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
Protein: PGK_ACIC5
Sequence: MSKLSIRDLDLAHKHVFMRVDFNVPLSEDGSEITDDTRIRETLPTIEYALRHKAKLILASHLGRPKGKVNPKYSLRPVVDRLRTLLDHDVTSRVNVAFSPDCVGDVAKELSLQLESGQVLLLENLRFHAEEEANDPEFARKLASLCEIYVNDAFGSAHRAHASTEGITHFVKQSAAGLLMEKELEYLGKALEAPAKPFVAIIGGAKVSDKIKVIDNLLNKVDALLIGGGMAYTFLKSQGQDVGKSLVEADKLDIAKAALDKAKEKGVRFLLPVDHILADKFAADAATQTFEGTGAFPAEWMALDIGPKSIELFTKEIAAADTIVWNGPMGVFEMPAFAKGTTAVAQAVADNVDAVSIIGGGDSVAAVKQAGVADKIKHISTGGGASLEFLEGKKLPGVEALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_CHLT3
Sequence: MVVLDGKKLSQEIKAELKTKVEQYKQEIQKVPGLTVIIVGEDPASQVYVRNKAKSCNEIGMASEVIELPASTSQEELLKKIADLNHNPNVHGILVQQPLPKHIDEFAVTLAIAPEKDVDGFHPENVGRLVLGHLDKCFVSCTPFGIIEILKRYNIETKGKHCVIVGRSNIVGKPMANLMVQKLAYMNCTVTVCHSATPDIATYTKQADILIAAIGKARFITGDMIKAGAVVIDVGINRIEATNTKSGYRLVGDVDFEAASQKASAITPVPGGVGPMTISMLLANTMKSFEHFLA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: AROE_JANMA
Sequence: MSTRTDHYAVIGNPIAHSKSPDIHARFAAQTQQDLKYDRLLAPLDGFLASVQEFIRNDGKGLNVTVPFKLEAYAMASRLSERARAAGAVNTLKFENGEMLGDNTDGVGLVTDIVRNAGVAVAGKTVLLLGAGGAARGVILPLLHEKPARLVIANRTHSKALDLAERFAPQPTLEVSDFGALDDAFDIVINATAASLASEVPPISPRVFAKRTLAYDMMYGAAPTPFMQFAAEHGATVRDGLGMLVEQAAESFYVWRNVRPETAAVFKELRDKL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: Y633_RICBR
Sequence: MKFFVYNPLLKTASLNIKVKAAAKSNDIKEFIIINDVLHLKLSIKAHAQQGKANEEIINFLAKEWQLLRSNLEITKGHTNSLKTILIKNIDEEYLNLILKPYIK
What are the official names of this protein?
UPF0235 protein RBE_0633.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: G6PI_ANAD2
Sequence: MPDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVTEETVRLLVALAEARGLPERRAAMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPEVHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSDLGPAMAYRALRAYAIRDLAFRFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVARHFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFREMDEHFRDAPLERNLPALIGLIGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNGKRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTHLVACDFIGFCQPLHALGRHHDLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGALVALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRYRARRGG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4CGT_ANTMA
Sequence: MGEEYKKTHTIVFHTSEEHLNSSIALAKFITKHHSSISITIISTAPAESSEVAKIINNPSITYRGLTAVALPENLTSNINKNPVELFFEIPRLQNANLREALLDISRKSDIKALIIDFFCNAAFEVSTSMNIPTYFDVSGGAFLLCTFLHHPTLHQTVRGDIADLNDSVEMPGFPLIHSSDLPMSLFYRKTNVYKHFLDTSLNMRKSSGILVNTFVALEFRAKEALSNGLYGPTPPLYLLSHTIAEPHDTKVLVNQHECLSWLDLQPSKSVIFLCFGRRGAFSAQQLKEIAIGLEKSGCRFLWLARISPEMDLNALLPEGFLSRTKGVGFVTNTWVPQKEVLSHDAVGGFVTHCGWSSVLEALSFGVPMIGWPLYAEQRINRVFMVEEIKVALPLDEEDGFVTAMELEKRVRELMESVKGKEVKRRVAELKISTKAAVSKGGSSLASLEKFINSVTR
What is the function of this protein?
Glycosyltransferase involved in the biosynthesis of aurones, plant flavonoids that provide yellow coloration to flowers.
What are the official names of this protein?
Chalcone 4'-O-glucosyltransferase, 4'CGT, Am4'CGT.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_KLEP7
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQYSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLEAESITEVILATNPTVEGEATANYIAELCAQYGVDASRIAHGVPVGGELEMVDGTTLSHSLAGRHKITF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MNMA_PSEMY
Sequence: MQAPSTQRVIVGMSGGVDSSVSALLLMEQGYQVEGLFMKNWDEDDGTEYCTAMDDLADAQAVCDRIGIKLHTANFAAEYWDNVFEHFLAEYKAGRTPNPDILCNREIKFKAFLDYALSLGADLIATGHYVRRRDIDGRTELLKGLDPNKDQSYFLHAVGGEQIAKTLFPVGELEKPQVRAIAEKYELATAKKKDSTGICFIGERRFSDFLKQYLPAQPGDIETTEGQVIGRHHGLMYHTIGQRQGLGIGGLKDASDDPWYVLRKDLTRNVLIVGQGNEHPWLFSRALLASDIYWVNPVDLSTPRRLTAKVRYRQSDQACTLEKTENGYRAVFDEPQRAVTPGQSVVFYDGEVCLGGGVIETAQAWYEDAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRPB_DANRE
Sequence: MGSQASKGGVAVEGKAAAADPAAVKTNGQENGHVKTNGDVSAKAEGDAATTNGSAEAAKESEAGAGDAIEPAPAAEGEAAKPEGEATKETPKKKKKKFSLKNSFKFKGISLKKSKKNAEVKEEAAAAAPATEEKPEENGAATEEKKEEEAKAEETPAAPVETPKAEEPAAKAEEPAAAKEEAAAPAVEATKQTEETNSTPAPSEQKE
What is the function of this protein?
Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation.
What are the official names of this protein?
MARCKS-related protein 1-B, MARCKS-like protein 1-A, MARCKS-like protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the MARCKS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain.
Protein: ILVD_MARMS
Sequence: MPVYRSKTTTSGRNMAGARALWRATGMTDDDFQKPIIAVVNSFTQFVPGHVHLKDMGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRINIPVIFVSGGPMEAGKTKLSENKLDLVDAMVIAADPTATDERVAEYERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTTLATHSDRRRLFLDAGRRIVDITKRYYENDEANWAPRSIASFEAFENAMTLDIAMGGSTNTILHLLAIAREAGVDFSMEDIDRLSRKVPQLCKVAPNSPKYHVEDVHRAGGIFALLGELDRGGILHNQCHTVHSKTMLEALKSWDIMRSPTPEIIEFYKAGPAGIPTQTAFSQSTRWPSLDGDRAEGCIRSIENAFSLEGGLAVLYGNIAVDGCVVKSAGVDESILVFEGRAHVTESQDEAVKNILDDKVEAGDIVIVRYEGPKGGPGMQEMLYPTSYIKSKGLGKACALLTDGRFSGGTSGLSIGHVSPEAAAGGAIGLVENGDRILIDIPNRSINVLLSDEELAKRRAAMEAKGAAAWKPVEMRPRKVSPALKVYAHFATSADKGAVRDISQID
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RBSD_ECOLI
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.  It also catalyzes the conversion between beta-allofuranose and beta-allopyranose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RESA_PLAFP
Sequence: NSITYNFENINSNVDNGNQSKNISDLSYTDQKEILEKIVSYIVDISLYDIENTALNAAEQLLSDNSVDEKTLKKRAQSLKKLSSIMERYAGGKRNDKKAKKYDTQDVVGYIMHGISTINKEMKNQNENVPEHVQHNAEANVEHDAEENVEHDAEENVEHDAEENAEENVEENVEEVEENVEENVEENVEENVEENVEENVEENVEEVEENVEENVEENVEENVEENVEENVEENVEENVEENVEENVEEYDEENVEEVEENVEENVEENVEENVEENVEENVEENVEENVEEYDEENVEEHNGI
What is the function of this protein?
May disrupt the normal intermolecular interactions of the cytoplasmic domain of band 3 and thereby facilitate the invagination of the red cell membrane which is necessary for the formation of the parasitophorous vacuole.
What are the official names of this protein?
Ring-infected erythrocyte surface antigen.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably located on the cytoplasmic face of the membrane where it associates with components of the membrane skeleton.
Protein: MURC_BACHK
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKSNVKEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMNQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFTDINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP5_ASPOR
Sequence: MARHGDTRSPSPVGSTYSSSRRSRRDDDRYERSRRDDGRSYRRSRSPEKRYRDRERDRDSYRRRDRSLDRRADYRDEDTYRPSRRDRSRDRRRSRDRDDDRDYRRRSRDRDFRSRRDDSRDRARRRTDDSADLKHKSRRDDSRERARDSVPRSREASKPSTPAANTGPTDDEKRAERLAKLEAWKQKQAAEKERKQREAAAAGGTRSILDEIDRKSGLSPAVGSPQSSATPIDAAPASYTGKFDPKAIAKNAAPAPAVKSVLGDDIAVPPSAKTSATFPSTKTEVQANKPSATSSKASSLKVKGNVGSFGLGTKQAADTEKASATKTLGFGEEESTRRKLERLPTPPLDDAKDSNKEEDVTAEDEDDDVDMQDGDTEEENAAAARAAAERREERLQNEARDSQSNGDVQMSDASNQKAPDKMEVDAQEEEEVDPLDAFMSELAESAPPKKTAGAKFAKAKPQQPEALFGDENDMDMTAVGDGDADDFLAIANKAKKKKDIPTVDHKKVEYEPFRKKFYTEPSDLAAMSEEEAASLRLELDGIKVRGVEVPRPVSKWSQCGLGVQTLDVIDRLGYSAPTSIQAQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIKDQRPLENMEGPVGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIADLKRGAEIIVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKILANVRPDKQTVLFSATFPRNMEALARKTLNKPVEIVVGGRSVVAPEITQIVEVRSEDKKFIRLLELLGNLYSTDENEDARALIFVERQEGADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEDQERYSVDIAKALKQSGQSVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERKTYKTGDEGEEEEEKEEKNEKAEEQFNKVLSSVQSAAAPSLPGVPKGIDLDGKITVHKTEKDANGSKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYATGKEPGPGENPKLYILVEGETELSVTNAMRELMRLLKEGTIAAADSDARAPVGGRYNVL
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase prp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PXPA_BURM7
Sequence: MEIDLNADLGEGCGSDEALLDLVTSANIACGWHAGGAQAMRDCVRWAVEKGVSIGAHPSFHDPENFGRKEMDLPASEIYAGVLYQLGALSAIAQAEGGRIAHVKPHGALYNQAAREPEIADAVVSAIHDFDPSLAVFGLAKSGFVDAAQQAGLVAVEEVFADRGYRADGSLVPRSQPGALVDDENEMLARTLEMVRGQRVRAVTGEWVPLNAQTVCLHGDGPHALAFAKRIRDALEAAGIDVHAPGALHAGERA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: CAPP_SHEON
Sequence: MTDMYASLRSNVSMLGQILGDTMRTHLGDSFLEKVEQIRKLAKDSRRGDEAAREQMLELLTALPDEELVPFAKAFNQFLNLANLSEQFHTISRNCDELVCVPDPVEQLLGRMLNGRVDQTKMLDCLKTLDIDLVLTAHPTEISRRTLIQKYAAIVDCLAEQENNQLSDRERQQINLRLRQLIAQIWHTNEIRRERPTPVDEARWGLSTIEESLWHAVPDFLRQLNDQVQERTGQQLPIDIAPVRFSSWMGGDRDGNPFVTAKVTQEVLDRNRHAAARLFLKDIVLLVGELSMEEANDELKAYTNNSCEPYRFVLRSLRQKLRDTIDYLNARIEGHNPEVDKSTLIWQESDLKAPLEMLYKSLYDCGMRLIANGLLLDILRRLACFGIHMLRLDIRQDAGRHCDVLAELTRYLGMGDFNHWDETEKQAFLLRELSNRRPLIPSNWQPSADVAEVLNTCRLIAKHPAKALGSYVISMASKPSDVLTVLLLLKETGCTHPMRVVPLFETLSDLNNAAACITDLLDIDWYRGYTKGMQEVMIGYSDSAKDAGVMAAAWAQYRAQEQLVAVCNQAGVKLTLFHGRGGSIGRGGGPAHKAILSQPPGSVDGRIRVTEQGEMIRFKFGLPKLAVQSLALYTSAVLEATLLPPPEPKQEWRNCMERIAEESVSAYRGIVREEPDFVAYFRAATPEVELGKLPLGSRPAKRRVDGGIESLRAIPWIFAWSQNRLMLPAWLGAGEALQAACQRGEIGLLQDMEREWPFFSTRISMLEMVYAKAEPNLARYYETCLVSTNLHHLGETLRQRLDLGIKVVLELTKSDTLMAHTPWNRESVKLRNPYIDPLNFLQTELLARTRKETSETPASEHVQLALMLTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: FRE7_YEAST
Sequence: MIEERDLVLSNGIHCIADIHSELYARLKKESQAATPWVYQKQYGKFVTYFVAVIIFLSLIKKLAFMYYDSSEEFLPEKKNSPTTPSVFLARIMTKLVAFNRYICYRKFPTLIFSYLGIPTSVGTFLVVMATTLYTLLYCFVPHPFYRPCAGFGSPPLSVRAGIMAISLVPFVFSLSGKINVIGWLVGLSYEKINIYHQWASILCLFFSWVHVIPFLRQARHEGGYERMHQRWKASDMWRSGVPPILFLNLLWLSSLPIARRHFYEIFLQLHWILAVGFYISLFYHVYPELNSHMYLVATIVVWFAQLFYRLAVKGYLRPGRSFMASTIANVSIVGEGCVELIVKDVEMAYSPGQHIFVRTIDKGIISNHPFSIFPSAKYPGGIKMLIRAQKGFSKRLYESNDDMKKILIDGPYGGIERDIRSFTNVYLICSGSGISTCLPFLQKYGPILHKTNLEVITLDWVVRHREDISWIRDEMCTLSNNLRQLFLDGKIVVRIYVCSDSTVPGIIKTFPQTIDTASDQSDLAKREKDTEFGQDDTESNSTFDKSNNEYKGLITIIPSKPDLNQVINDYQIGFRNCFICSGSDSLRYTVGNSVAGLQAKVFSNKNVEECYLHSESFGY
What is the function of this protein?
Cell surface metalloreductase.  May be involved in copper homeostasis.
What are the official names of this protein?
Ferric/cupric reductase transmembrane component 7, Ferric-chelate reductase 7.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.