PharMolix/UniProtQA huggingface dataset:
Protein: CH60_CLAM3
Sequence: MAKIIAFDEEARRGLERGLNILADAVRVTLGPRGRNVVLEKKWGAPTITNDGVSIAKEIELDDPFEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGADPISLKRGIEKAVAAVTEELKAAAKEIETKEEIAATASISAGDSTIGAIIAEAIDKVGKEGVVTVEESNTFGTELELTEGMRFDKGYLSQYFVTDPERQEAVFEDAYILIVNSKISNIKDLLPIVDKVIQSGKQLLIIAEDVDGEALATLVVNKIRGIFKSVAVKAPGFGDRRKAQLQDIAILTGGQVIAEEVGLKLENVTLDLLGTARKVVITKDETTIVEGGGDATEIAARVQQIRNEIGNTDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALIQAGKLAFEKLQLEGDEATGANIVRVAVDAPLKQIALNAGLEPGVVAERVRNLPSGHGLNAATGEYVDMLAAGINDPVKVTRSALLNAASIAGLFLTTEAVVADKPEKNPAPAGDPTGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DINI_ECO57
Sequence: MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRYAAANNLSVIGATKEDKQRISEILQETWESADDWFVSE
What is the function of this protein?
Involved in SOS regulation.  Inhibits RecA by preventing RecA to bind ssDNA.  Can displace ssDNA from RecA (By similarity).
What are the official names of this protein?
DNA damage-inducible protein I.
What is the protein family that this protein belongs to?
Belongs to the DinI family.
Protein: TM11E_HUMAN
Sequence: MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
What is the function of this protein?
Serine protease which possesses both gelatinolytic and caseinolytic activities.  Shows a preference for Arg in the P1 position.
What are the official names of this protein?
Transmembrane protease serine 11E, Serine protease DESC1, Transmembrane protease serine 11E2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Transmembrane protease serine 11E catalytic chain]: Secreted. Note=Activated by cleavage and secreted.
Protein: TIG_ECOL5
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MTP_MEGAM
Sequence: MLRLAGLLLCVTSFLSTSSLGANAGPRLDNDRLYRYSYSAELGLNRPTGSTRGNPGFRISSDVDISLVWRNPEIQDEQLLQVQISNVQVESAGKHSRKNNIFHGSSTESILGKVRLEALQRPFMVLWKMGKIRSLYAHKGEPATIKNLKRGVASMLMMQLKSGKMMEADSSGKCLVEYKATKHQVIRTKHLDTCKTQEKGFTTYSPVLGVSGKSASETVITLENGIIKSADVEETHILSINARHTAATKVLSRQSLTLKKIEVGPTEVAGKDVAGVVKSLDDKFMSVGVIVEKVKAKCKGCPNLMDTWKAVRSKLEPDSLSKAEAPRSFLTLLHSLRKASKAEILTVLRNCSKTALPQLVDAVTSAQTTSSLSAILEFLDFSKKEGLVLQERFLYACGFASHPTETMLQSLLDVSQGKIGSPDIKESVVIIMGALLRKLCLKGACELPTVVKVKELLLAGPDSTQVESEVQMYLLALKNALLPEAVPLLAKYAESEVGAYSTIAITALQRYDPVLITPEVKKTVNRIYHQNQRIYEKNVRAAAADVIMSSSPSYMEVKNVLLSIGHLPHEMNKYMLSKVQDILRFEMPACKLVQQVMKDMISHNYDRFSKTGSSSAFSGFMAQTADVISTYNLDILYSGSGVLRRSNMNIYGQSNNALLHGLQVTIEAQGLESLIAATADEGEEELESFAGMSALLFDVQLRPVTFFKGYSDLMSKMFSMSGDPINVVKGLILLTDHSQVIPLQSGLRASAEFQGGLAIDISGGMEFSLWYRESKTSVNNRGALVVIGNVTVDMDFVSAGVEVGFETEASLDFITTVQFSEYPFLVCMQMDKTTFPFREMVSKQEKLPSGQTFSTKRSRDQLVPGSEFPLHQENSNMCKKVFEQAW
What is the function of this protein?
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces.  Required for the secretion of plasma lipoproteins that contain apolipoprotein B.
What are the official names of this protein?
Microsomal triglyceride transfer protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: Y044_RICTY
Sequence: MRILIILSIILCSFFARADLEYIDNDIYNYNGGRNENGCLEVYDPYEKFNRKVFAFNSVLDHIILRPLAVGYKNITNDYIKARVNSFVSNVYTPLTAVNYGLQLNYDKTIKSVWRFLINTTLGIGGLFDVASKVGLQSDRQTFGSTLAHYGVAPGPYLVLPIIGSTNARDMTDSVITNYAINPLMYYTHNDFDLGILAISKITDRYVVLPFSDYVMKNSTDPYVAIRSALHRTREASVQYPENFKCPKPKN
What are the official names of this protein?
Uncharacterized protein RT0044.
What is the protein family that this protein belongs to?
Belongs to the MlaA family.
Protein: DNAA_SALPA
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNTFCGADAPQLRFEVGTKPVTQTLKTPVHNVVAPAQTTTAQPQRVAPAARSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKIADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A3X1_LOXLA
Sequence: ADNRRPIWNLGHMVNALKQIPTFLXDGANA
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  In vivo, intradermal injection induces dermonecrosis (PubMed:8819009).  Induces hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LlSicTox-alphaIII-1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBSK_HALH5
Sequence: MKTPNITVVGSINMDMVTITDVVPVQGETVLGKDFRTVPGGKGANQAVAAARLGANVRMIGRVGDDPFGHVLTENLAKEGIITDSVKPVTDCTSGVATILLSDRDNRIIVTKGANEHVTPDYVAAFEQELAASDVVLLQLEIPLETVAYVLEFCAKHHVTTVLNPAPAQKLPDAAWTDATYISPNENECLQLFGDEPDANLRQKLIMTKGADGVQFYENDEQVQVESFRVEPVDTTGAGDTFNGAFAVALGGGTVKEAVRFANAAAALSVQSFGAQGGMPTKAQVQSFLQEQGG
What is the function of this protein?
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium.  The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
What are the official names of this protein?
Ribokinase, RK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
Protein: PYRB_STAAT
Sequence: MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL23_STRZJ
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: AL7A1_BRANA
Sequence: MGSASKEYEFLSEIGLSSSHNLGNYVGGKWLGNGPLVSTLNPANNQVLPIAQVVEASLEDYEIGLKACEEAAKTWMQVPAPKRGDIVRQIGDALRSKLDYLGRLLSLEMGKILAEGIGEVQEVIDMCDFAVGLSRQLNGSVIPSERPNHMMLEMWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNHLPGAIFTAMCGGAEIGEAIAKDTRIPLVSFTGSSKVGLTVQQTVSARSGKTLLELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYKQVKIGDPLEKGTLLGPLHTPESKKNFEKGIEVIKSQGGKVLTGGKAVEGEGNFVEPTIIEISSDAAVVKEELFAPVLYALKFKTFEEAVAINNSVPQGLSSSIFTRSPDNIFKWIGPMGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRSTW
What are the official names of this protein?
Aldehyde dehydrogenase family 7 member A1, Antiquitin-1, Brassica turgor-responsive/drought-induced gene 26 protein, Btg-26.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: AMPEP_HELPY
Sequence: MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVLAEVVESSDLVQSAIDLIVKSSVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESLSERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVFKREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL
What is the function of this protein?
Hydrolyzes the N-terminal amino acid residue from a polypeptide chain, with a preference for substrates containing multiple alanine residues.
What are the official names of this protein?
Aminopeptidase HP_1037.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: PUUD_ECOLI
Sequence: MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIALPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMAIINAALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQVEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALGVQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL
What is the function of this protein?
Involved in the breakdown of putrescine via hydrolysis of the gamma-glutamyl linkage of gamma-glutamyl-gamma-aminobutyrate.
What are the official names of this protein?
Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD, Gamma-Glu-GABA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
Protein: ORN_STRGR
Sequence: MNDRMVWIDCEMTGLSLADDALIEVAALVTDSELNVLGEGVDIVIRPPDAALETMPEVVRQMHTASGLLDELAGGTTLADAEEQVLAYVREHVKEPGKAPLCGNSVGTDRGFLARDMRELEGYLHYRIVDVSSVKELARRWYPRAYFNSPAKNGNHRALADIRDSITELRYYREAVFVPQPGPDSERAKEIAARLSAPAAP
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCHA_ECO57
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAI_SALPA
Sequence: MRSVLTISVGLLFGLALSSVAHANDHKILGVIAMPRNETNDLALKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: SPT52_ARATH
Sequence: MSQYSDDDYSHEDDSEMEDEDEEDEYEPRSSRKGRSGKKRGRSNSDSDGRRGSKKKSSGSAFIDWEVEVDDDVEDDDDDVDVEDGKQQLKFGDFSLCFIVSGEADLPNEDSDHRRQYYQRGFHPHEEDVDELEKRTLERLSTKYAKDDYELDDVNDVDQQALLPSVRDPKLWLVKCAIGREREVAVCLMQKIVDRGSEFKIRSAIALDHLQNYVYIEADMEAHVKEAIKGMRNIYANQKILLVPIKEMTAVLSVESKAIDLSRDSWVRMKLGIYKGDLAQVVDVDNVRKRVTVKLIPRIDLQALANKLEGTENVKKKAFAPPPRFMNIDEARELHIRVEHRRDPMTGDYFENIGGMLFKDGFLYKKVSTKSIAAQNVTPTFDELERFKRPNENGEIDFVDESTLFANRKKGHFMKGDAVIVIKGDLKNLKGWIEKVDEENVLIRSEMKDLPNPIAVNGRELCKYFEPGNFVKVVSGIHEGGTGMIVKVDQHMLIILSDTTKEHICVFADHVAKSAEVTKGVTKIGDYELHDLVILSDFSFGVILKLDSEAIQILKGVPDSSEVSIVKASEIKYKIWKKINVQDRYKNVVAVKDVVRVIEGPSKGKQGPVVQIYKGVLFIHDRHNLEHTGFICTRCSSCVLAGGNFKTPALVPPSPRRFQRADMGYNPGAGGRHQGGRGRRGDDHLVGTYVKIRLGPFKGYSGRLVEVKDKLVRVELEAKIVTVERKAISDMTDNVVATPQYNMGSQTPMHPSRTPLHPCMTPMRHSGATPIHDGMRTPMRGRAWNPYMPMSPPRDNWEDGNPGSWGTSPYEAATPGSDWGSSTPGRSSYRDAGTPINNANAPSPMTPSSTSYLPTTPGGQAMTPGTDLDVMSLDIGGDAETRFIPGILVNVHKAGEDRNPGVIRDVLPDGSCVVALGHRGEGETIRATQNKVSLVCPKKNERVKILGGKYCGSTAKVIGEDGQDGIVKLDESLDIKILKLTILAKLVHE
What is the function of this protein?
May regulate transcription elongation by RNA polymerase II.  May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity).
What are the official names of this protein?
Putative transcription elongation factor SPT5 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBJQ_SALPA
Sequence: MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RS6E_SULIY
Sequence: MPDFKIVISDPQSVEPKRIKVKAKANDQIKSIAGEKEGKAVPQAKVNEKTKQLLNIDTLITLEITKQEGDKKVKVKSHFKVEVDNNVPDNEVWISKTMAEKFGAEDFEAIAYRTKTLQISIDQDKATNLVGLKIGDTFEANQLIGLPVKLKITGGSDNSGFPMRFDVTGAAKRKILLSGPPGFYPNEDGERRRKTIRGNTISQEIVQINTIIVR
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: DPO4_DESPS
Sequence: MYMRKIIHIDMDAFFASIEQRDRPELRKKPLIVGGLPRGRGVVATCCYEARRYGIHSAMSANRAYKLCPHAVFVKPRMVLYKEVSLQIMAIFREYTKKVEPLSLDEAFLDVTEYLQINGSATLLAREICALIKLRTDLSASAGVSYNKFLAKIASDLKKPGGISTVPPEEARQFIDRLSIGKFYGVGKITKSKMQSLGIQTGKDLRQYSKDFLMKRFGKAGSFFFYNARGLDERPVCPYQNRKSIGKETTLVQDTNRPEEIRDILINLSSLLGKALENNSQLAQTLTLKIRYSDFTTTTRSLSLQKPFSCPADIEECLPSLLTNCNLTHKPIRLLGISLSKLTYIGSAPRPIPLPFPKDRRSNCLNRFFAIKEESP
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STRP7
Sequence: MSEAIIAKKAELVDVVAGKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: Y810_STRSV
Sequence: MSEKKIQLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPTLVPKFLQLVEGTTDNDKLALVVDMRSRSFFLQIQNVLDELEQNENIDFKILFLDAADKELVARYKETRRSHPLAADGRILDGIKLERELLAPLKNLSQNVVDTTDLTPRELRKTISEQFSNQADMHSFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKPELRNQTGLDKDVFDYVMNHAESEEFYKNLLGLIEPILPGYQKEGKSILTIAVGCTGGQHRSVAFAQRLADDLAKNWPVNSSHRDKNRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SSA_0810.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RPOC_STRPI
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UBID_ECOLI
Sequence: MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HME1_MOUSE
Sequence: MEEQQPEPKSQRDSGLGAVAAAAPSGLSLSLSPGASGSSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPHLPPHPPPPPPPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPLPQLLVASAAAGGGAAAGGGSRVERDRGQTGAGRDPVHSLGTRASGAASLLCAPDANCGPPDGSQPATAVSAGASKAGNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGGSGGNAGSPGAQGAKFPEHNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE
What is the function of this protein?
Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb.
What are the official names of this protein?
Homeobox protein engrailed-1, Homeobox protein en-1, Mo-En-1.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOAC_YERPE
Sequence: MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLLLTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RS11_HUMAN
Sequence: MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S11, Small ribosomal subunit protein uS17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.