PharMolix/UniProtQA huggingface dataset:
Protein: RLIG_ASFK5
Sequence: MSNESFPETLENLLSTLQTKQQNAIQSEVIKWLHSFCETFHLKIHCHKQFIPSGEKKWPKIPTQETQENTQPPHHVHRVVLSRAQPLKVQESLLTTMCNGLVLDANTWTCLAVPPPAPFQQVTRQVQHYYRNKFYEVAAIQDGTLLTIYYWDDPEHGPSWCLASTHGYDVSNYCWIGDKTFAELVYELLQQHSTCNVTLEKNKTRGTRLFFNELNRDYCYTIGIRHHNLQPLIHDPQNIWAIQSTNLKTLKTVYPEYYGYVGIPGIQSQVPELPQFELPYLIRSYRTAMNQAKNAIKNGKKEKEYFNYGYLLISRAPAITKSISIVLLKSPLLVFLQKSVYQKKYNISSSLRLEFIILQNYLMQHFRDNFIALFPQYISYYMKYQNMLNMIIHSIAIKDKDHPFAGAVVKKVLEDIENAENIIDHTTIQNYAYQSKYAMLYLSIITHF
What are the official names of this protein?
Putative RNA-ligase, pM448R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus M448R family.
What are the subcellular locations of this protein?
Virion.
Protein: PNP_AZOC5
Sequence: MFDIHREELDWGGRTLVLETGKMARQADGAVFASYGDTTVLATVVSAREPKPGQDFFPLTVNYQEKTYAAGRIPGGYFKREGRPSEKETLVSRLIDRPIRPLFADGYKNDTQVVVTVLAHDLENDPDVLSMVAASAALTLSGVPFMGPIGGARVGFVGDEYVLNPTIEELKDSALDLVVAGTSDAVLMVESEAKELSEEVMLGAVMFGHRHFQPVIEAIIRLAEKAAKEPRPFEPVDHSALEAKIREIAEADLRAAYKIKQKQARYEAVGAAKSKVKKYFEQLAIDGQEAPKAQDVAEVLKGLEAKIVRWAILDDGIRIDGRDVKTVRPIVSEVGILPRAHGSALFTRGETQALVVATLGTGEDEQFIDSLEGTYKEHFLLHYNFPPFSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAKHEFPYTLRVVSEILESNGSSSMATVCGTSLSLMDAGVPLKSPVAGIAMGLILEGEKFAVLSDILGDEDHLGDMDFKVAGTESGVTALQMDIKIAGITEEIMKVALAQAKDGRAHILGEMSKALTSARAELGEHAPRIEVMKIAVDKIREVIGSGGKVIREIVEKTGAKINIEDDGTIKIASASGDSIKAAINWIKSIASEPEVGAIYDGTVVKVVDFGAFVNFFGSKDGLVHISQLSKERVAKSSDVVKEGDKVKVKLVGFDERGKTRLSMKAVDQTTGEDLEAKAKSEKDAAKEGDEAGAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2FB_XENLA
Sequence: MSAEKGELDLNGAKQNTGMWLVKLPKYLAQQWAKATGRGEVGKLRIVKNQGKTEVSFTLNEELASIQDIGGKPASSLVSTPREHPFLLQSVGGQTLTVLTESLSGQSEDKSENRVIDKLALEGIVVHRAECRPAASDNYMQMKRKQIEESSKPKRQSQQLEKAVTSNYKPVSNHQYNIEYEKKKKDDGKRARVDKHQVLDMLFSAFEKHQYYNIKDLVDITKQPVTYLKEILRDIGIYNMKGTHKNTWELKPEYRHYQGEDKSD
What is the function of this protein?
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.
What are the official names of this protein?
General transcription factor IIF subunit 2, Transcription initiation factor IIF subunit beta, TFIIF-beta, Transcription initiation factor RAP30.
What is the protein family that this protein belongs to?
Belongs to the TFIIF beta subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IDI2_SULIY
Sequence: MPDIVNRKVEHVEIAAFENVDGLSSSTFLNDVILVHQGFPGISFSEINTKTKFFRKEISVPIMVTGMTGGRNELGRINKIIAEVTEKFGIPMGVGSQRVAIEKAEARESFAIVRKVAPTIPIIANLGMPQLVKGYGLKEFQDAIQMIEADAIAVHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGISMETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVPTAASIMEVRYSVPDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSAIEGKESLEQFFRKIIFELKAAMMLTGSKDVNALKKTSIVILGKLKEWAEYRGINLSTYDKVRKRE
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_SHISS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GLMU_HAEIG
Sequence: MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGDLMRSHLANEQVNWVLQTEQLGTAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANADQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKNVVIGNDVEIKPYSVLEDSVVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGP_EBORE
Sequence: MGSGYQLLQLPRERFRKTSFLVWVIILFQRAISMPLGIVTNSTLKATEIDQLVCRDKLSSTSQLKSVGLNLEGNGIATDVPSATKRWGFRSGVPPKVVSYEAGEWAENCYNLEIKKSDGSECLPLPPDGVRGFPRCRYVHKVQGTGPCPGDLAFHKNGAFFLYDRLASTVIYRGTTFAEGVIAFLILSEPKKHFWKATPAHEPVNTTDDSTSYYMTLTLSYEMSNFGGEESNTLFKVDNHTYVQLDRPHTPQFLVQLNETLRRNNRLSNSTGRLTWTVDPKIEPDVGEWAFWETKKNFSQQLHGENLHFQILSTHTNNSSDQSPAGTVQGKISYHPPTNNSELVPTDSPPVVSVLTAGRTEEMSTQGLTNGETITGFTANPMTTTIAPSPTMTSEVDNNVPSEQPNNTASIEDSPPSASNETIDHSEMNSIQGSNNSAQSPQTKATPAPTASPMTLDPQETANISKPGTSPGSAAGPSQPGLTINTISKVADSLSPTRKQKRSVRQNTANKCNPDLHYWTAVDEGAAAGLAWIPYFGPAAEGIYIEGVMHNQNGLICGLRQLANETTQALQLFLRATTELRTYSLLNRKAIDFLLQRWGGTCRILGPSCCIEPHDWTKNITDEINQIKHDFIDNPLPDHGDDLNLWTGWRQWIPAGIGIIGVIIAIIALLCICKILC
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in GP2, releasing the fusion hydrophobic peptide.
What are the official names of this protein?
Envelope glycoprotein, GP1,2, GP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[GP2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site. SUBCELLULAR LOCATION: [GP1]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=GP1 is not anchored to the viral envelope, but forms a disulfid-linked complex with the extravirion surface GP2. In the cell, both GP1 and GP2 localize to the plasma membrane lipid rafts, which probably represent the assembly and budding site. GP1 can also be shed after proteolytic processing. SUBCELLULAR LOCATION: [Shed GP]: Secreted. Note=GP2-delta bound to GP1 (GP1,2- delta) is produced by proteolytic cleavage of GP1,2 by host ADAM17 and shed by the virus.
Protein: SEC13_HUMAN
Sequence: MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ
What is the function of this protein?
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway.  Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238).  It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
What are the official names of this protein?
Protein SEC13 homolog, GATOR complex protein SEC13, SEC13-like protein 1, SEC13-related protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Lysosome membrane. Note=In interphase, localizes at both sides of the NPC.
Protein: ISPD_PROMA
Sequence: MHLLIAAAGSGKRMGANCNKLLLKVAGRSVLAWTLDAVKRSNSISWIGIVGQPSDKEAIVSIFDECALQAKWINGGDSRQESVQLGLEGLPLDAKHVLIHDGARCLVEPELFDKCSEMLRQGVSVIAATPVIDTIKKVSLDGFINKTFNRAELWAAQTPQGFNVEQLRQGHKKALVNNWTVTDDASLFEKLGWPVKILESSPSNIKVTTPFDLLIADALLSSRGAD
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CDY2_HUMAN
Sequence: MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNCKLFAASKNVRRKAASTLSDTKNMEIINSTIETLAPDSPFDHKKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSHPGAEQTGIQNKTQMHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRGQPFIKKMHFTIRLTESAITYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELASYNAIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF
What is the function of this protein?
May have histone acetyltransferase activity.
What are the official names of this protein?
Testis-specific chromodomain protein Y 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: FEOB_LEGPN
Sequence: MTHALLIGNPNCGKTTLFNALTNANQRVGNWPGVTVEKKTGEFLLGEHLIEITDLPGVYSLVANAEGISQDEQIAAQSVIDLEYDCIINVIDACHLERHLYLTSQLFELGKPVVVALNMMDIAEHRGISIDTEKLESLLGCSVIPIQAHKNIGIPALQQSLLHCSQKIKPLKLSLSVAAQQILNDLENQLISKGYKNSFAYYFSRRLAEGDTLIGEKAFTESLLIKLQETEQNLDVLLADARYQKIHEIVTLVQKKHSDASEHFTAKLDKLVLHRFLALPIFFAMMYLMFLFAINIGGAFQDFFDISTETIFVQGSGWLLQQLHAPNWVIALVANGVGKGINTTITFIPVIAAMFFFLSLLETSGYMARAAFVVDKAMRAMGLPGKSFVPMIVGFGCNVPAIMAARTLDSERDRLLTVMMSPFMSCSARLAIYAVFVAAFFPSGGHNVVFSLYLIGILMAVFTGYILRKTTLKGHASPLILELPAYHRPSLRRLLRETSLRLRFFVYRAGKLIIPICVILGGLNAITWGGGISSGEANTDSLLSIIGQWITPLFAPMGIHQDNWPATVGLLTGMLAKEVVVGTLNSLYAQVGHVGEITAAHFDFWGGIKAAFGSIPANLSELGSALWNPVSASAADSELSQSVYGIMSRRFDGAVGAYAYLLFVLLYIPCVSTMAVIRQEANKRFMWTSIVWSFVVAYATSVVFYQGAKFLDHPQQSMVWILAMSLSLLFVLAVFRYSQYGMGRQNAAANT
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.  Seems to be required for optimal intracellular infection of macrophages, to be important for growth and/or survival in iron-restricted amoebae.  It also plays a key role in extracellular growth under iron-limited conditions.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QSOX1_ARATH
Sequence: MSLIHLFLLLGLLSLEAAASFSPGSRSILRDIGSNVADQKDNAIELNATNFDSVFQDSPAKYAVLEFFAHWCPACRNYKPHYEKVARLFNGADAVYPGVVLMTRVDCAIKMNVKLCDKFSINHYPMLFWAPPKRFVGGSWGPKQEKNEISVVNEWRTADLLLNWINKQIGSSYGLDDQKLGNLLSNISDQEQISQAIFDIEEATEEAFDIILAHKAIKSSETSASFIRFLQLLVAHHPSRRCRTGSAEILVNFDDICPSGECSYDQESGAKDSLRNFHICGKDVPRGYYRFCRGSKNETRGFSCGLWVLMHSLSVRIEDGESQFAFTAICDFINNFFMCDDCRRHFHDMCLSVKTPFKKARDIALWLWSTHNKVNERLKKDEDSLGTGDPKFPKMIWPPKQLCPSCYLSSTEKNIDWDHDQVYKFLKKYYGQKLVSVYKKNGESVSKEEVIAAAEEMAVPTNALVVPVGAALAIALASCAFGALACYWRTQQKNRKYNYNPHYLKRYNSNYMVMNTFSNTESEREKER
What is the function of this protein?
Sulfhydryl oxidase involved in the regulation of cation homeostasis.  Positively regulates shoot accumulation of K(+) and inhibits accumulation of toxic cations.  Acts at the level of root K(+) efflux systems involved in xylem loading (root symplast-xylem interface).
What are the official names of this protein?
Sulfhydryl oxidase 1, Quiescin-sulfhydryl oxidase 1, AtQSOX1.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Associated with the cell wall.
Protein: RL17_MYCPN
Sequence: MSYINKPGKTSAWRVMTVRQQVSAVLAYGKIETTLKKAKNTQKRLDKLITLAKVDNFNNRRQVKKWLLNTNLFDVDQLMDHLFSKVAPKYEKTPGGYSRVLKLGPRRGDATEMAILQLTDAKYK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ASSY_NITWN
Sequence: MSKKVQKVVLAYSGGLDTSIILKWLQTTYGAEVVTFTADLGQGEELEPARRKAQLLGIKDENIFIEDLREEFVRDYVFPMFRANAVYEGQYLLGTSIARPLIAKKQIEIAEKVGADAVAHGATGKGNDQVRFELGYYALKPDITIIAPWREWDLRSREQLIAFAEQHQIPIAKDKRGEAPFSVDANLLHASSEGKVLEDPAQEVPDYVYSRTIDPEAAPDQPTYITIDFEQGDAVAIDGGKMSPATLLAKLNELGRANGIGRLDLVENRFVGMKSRGMYETPGGAILLVAHRGIEQITLDRGAAHLKDELMPKYAELVYNGFWFSPEREMLQAAIDQSQRYVTGQVRLKLYKGNVILVGRDSAYSLYDQDLVTFEEGAVAYDHRDAAGFIKLNALRLRTLGQRRKKLGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SHEAM
Sequence: MPWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALFDADFDLAPVVDMLKSLPFLGSELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWREVPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGKDIIDFGCGSGILAVAALKLGAAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELAPLIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_ACTP7
Sequence: MKKTAVLNAQLSGVIASLGHTDGLTICDAGLPIPSEQQCVDLALTKGIPSFLSTLEVVLTELFVERILLAEEIKQANPTIEQQLLEMINKLAQTQGRQIEIEYVVHSEFKQRSNQAKAVVRTGECSPYANVILYSGVPF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_VEREI
Sequence: MQALYDLPAPAKLNLFLHIIGRRADGYHLIESVFMLIDWCDTLHFECRADGAISRQDLGAPLPAADLSIRAAHALRAATGCRQGAHIGLLKRLPAQAGIGGGSSDAATTLLALNRLWGLGLSLSALEKIGVTLGADVPFFVRGRNARVAGIGEIITPLAHGQLPPACFAVVKPAAGLETKAIFSSPLLKRASGSATISGFAAADFGRDGDCYQDADFCRNDLQPVAQALCPEVTQAIEWLRARGLQGRMTGSGSAVFAQIPQAPDLGHVGDLGAAPEGWQVRVCENLMLHPLAGWAADED
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TRMD_STRPM
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLLERYDFSEEERKLLDKIKEALGQGED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BACAC
Sequence: MSQEKQVFSIDLAGRQLTVETGQLAKQANGAVLVRYGDTAVLSTATASKEAKNVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFADGFRNEVQVVSIVMSVDQDCSSEMAAMLGSSLALSISDIPFEGPIAGATVGRINGEFVINPTVEQQEQSDIHLVVAGTKDAINMVEAGADQVPEETMLEAIMFGHDEIKRLIAFQEEIVQAVGKEKSEVKLYEVDADLNQAVREMAEKDMHSAIQVHEKHAREDAINEVKKRVIEHYEAQEADADTLGQVNEILYKIVKEEVRRLITVEKIRPDGRKGDEIRPLASEVGILSRTHGSGLFTRGQTQALSICTLGALGDVQILDGLGVEESKRFMHHYNFPSFSVGETRPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICGSTLAMMDAGVPLKAPVAGIAMGLVKTGEHYTILSDIQGMEDHLGDMDFKVAGTAHGVTALQMDIKIDGLSREILEEALQQAKVGRVHILNHMLSVIAEPRTELSAYAPKIITMTINPDKIRDVIGPSGKQINKIIEETGVKIDIEQDGTVFISSINQEMNDKAKKIIEDIVREVQVGEIYEGKVKRVEKFGAFVELFSGKDGLVHISELALERVGKVEDVVKIGDVITVKVIEIDKQGRVNLSRKVLLKEEQEKEAAKEENKQEQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODL_MONPV
Sequence: MAVCIIDHDNIRGVIYVEQVHGKDKVLGSVIGLKSGTYSLIIHRYGDISRGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGVIGISYINEKIIHFLTINENGV
What is the function of this protein?
Superoxide dismutase-like protein with no enzymatic activity.
What are the official names of this protein?
Cu-Zn superoxide dismutase-like protein OPG175.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
Protein: DOPR3_CAEBR
Sequence: MLTGQHHIPGIESPLMVVLWRVAAGVFLPLVPTMAVFGNVLVILSVYRERNLQTVTNMLIVSLAVSDLFVAIGVMSFGVYYEWNGFKWGLGSFFCHVYQALDVACSTASILNLLAISLDRYIAIGHPISYAQYGARGGRAMISITIVWGVSCAVALPLLLGVNPMENDQCELANPWFNMISSIFSFFIPCIAMIILYTIIFRRLRQRERARSLRQAQRSETDKISSALLGGAQIARQMGKHFKNRTDQILLEISFQTSSFPTISESSDDGSTISPMINSFNNFLPKKSQYPSTLIPAIPECGSMPNLTIIERPAPPEKEKDIELSIMDLHDTVEMLDDKYTSAMITRSFGEELEEILPFIDGSTSVKNSREQLHATRSNTSTTRLLDVKPELRSISVPSIQDEKKMNSRPPENPFAHQNGTNKQRLLPNPGILMKSKSTTLLKTNGYLDTDSLNNNRNSHKKSTADLLPNDDYSFTDSMRVYKNRLFKSLSRATSGWNKPRPSRHMVKKATKQMRREHKATVTLAVVLAVFLFCWLPFFILHLSNSICLVIDSNSDCIGFLPLYLATWLGYLNSSLNPLIYTVFDQRFRNAFRNILSCGFFKKR
What is the function of this protein?
Receptor for dopamine.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  In terms of antagonist responses, would be classed with the D2-like dopamine receptor group.  Mediates the effect of dopamine on the inhibition of locomotion.  Acts as an antagonist of dop-1 (By similarity).
What are the official names of this protein?
Dopamine receptor 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTFR1_HUMAN
Sequence: MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISLPDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPKSESEATSERVLFGPHMLKPTGKMKALIENVSDS
What is the function of this protein?
May play a role in mitochondrial aerobic respiration.  May also regulate mitochondrial organization and fission (By similarity).
What are the official names of this protein?
Mitochondrial fission regulator 1, Chondrocyte protein with a poly-proline region.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
Protein: MSS4_RAT
Sequence: MEPCELQNELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPDLVDGSNPDGDVLEEHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE
What is the function of this protein?
Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily.  Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein.  Might play a general role in vesicular transport.
What are the official names of this protein?
Guanine nucleotide exchange factor MSS4, Rab-interacting factor.
What is the protein family that this protein belongs to?
Belongs to the DSS4/MSS4 family.
Protein: ODO1_STAA8
Sequence: MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSTIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMHSFIEQVQKELRQAHDKINKADKMDNPDMEKPADLALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: ASPDH_XENTR
Sequence: MSEERRMRIGVVGYGHIGKYLVDKIVREGANHSMELAFVWNRRREKLSGAVDPRLQLQDLSDCQKWAADLIVEVAHPCITREYGEKFLSVAHFLVGSPTALADTVTEAKLRERARLSGNTLYVPCGALWGAEDIFKMAERGTLKALRITMTKHPNSFKLEGDLVQKNQEAMSNRTVLYEGPVRGLCPLAPNNVNTMAAACMAAHTLGFDGVVGVLVSDPSVPDWHFVDIEVTGGTIEKTGQVFSVKTSRRNPAAPCSVTGSATFASFWSSLLACKGHGGRVYIC
What are the official names of this protein?
Aspartate dehydrogenase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: Y2751_MYCVP
Sequence: MTLPLLGPMSLSGFEHPWFFLFFLVVLGLVALYVIVQMGRHRRMLRFANMELLESVAPKRPSRWRHLPAVLLILSLMSFTVAMAGPTHDVRIPRNRAVVMLVIDVSQSMRATDVAPNRLVAAQEAAKQFADQLTPGINLGLIAYAGTATVLVSPTTNREATKAAIDKLQLADRTATGEGIFTALQAVATVGAVIGGGDEPPPARIVLMSDGKETVPSNPDNPKGAYTAARTAKDQGVPISTVSFGTPYGYVEINDQRQPVPVDDEMLKKIADLSGGDAFTASSLEQLKQVFTNLQEQIGYETIKGDASVGWLRIGSLVLALAALGALLINRRLPN
What are the official names of this protein?
UPF0353 protein Mvan_2751.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.