PharMolix/UniProtQA huggingface dataset:
Protein: DRL30_ARATH
Sequence: MADIIGGEVVTELVRQLYAVSQKTLRCRGIAKNLATMIDGLQPTIKEIQYSGVELTPHRQAQLRMFSETLDKCRKLTEKVLKSSRWNMVRQLLHVRKMENLQSKVSSFLNGQLLVHVLADVHHVRADSEFRFDRIDRKVDSLNEKLGSMKLRGSESLREALKTAEATVEMVTTDGADLGVGLDLGKRKVKEMLFKSIDGERLIGISGMSGSGKTTLAKELARDEEVRGHFGNKVLFLTVSQSPNLEELRAHIWGFLTSYEAGVGATLPESRKLVILDDVWTRESLDQLMFENIPGTTTLVVSRSKLADSRVTYDVELLNEHEATALFCLSVFNQKLVPSGFSQSLVKQVVGECKGLPLSLKVIGASLKERPEKYWEGAVERLSRGEPADETHESRVFAQIEATLENLDPKTRDCFLVLGAFPEDKKIPLDVLINVLVELHDLEDATAFAVIVDLANRNLLTLVKDPRFGHMYTSYYDIFVTQHDVLRDVALRLSNHGKVNNRERLLMPKRESMLPREWERNNDEPYKARVVSIHTGEMTQMDWFDMELPKAEVLILHFSSDKYVLPPFIAKMGKLTALVIINNGMSPARLHDFSIFTNLAKLKSLWLQRVHVPELSSSTVPLQNLHKLSLIFCKINTSLDQTELDIAQIFPKLSDLTIDHCDDLLELPSTICGITSLNSISITNCPRIKELPKNLSKLKALQLLRLYACHELNSLPVEICELPRLKYVDISQCVSLSSLPEKIGKVKTLEKIDTRECSLSSIPNSVVLLTSLRHVICDREALWMWEKVQKAVAGLRVEAAEKSFSRDWLDD
What is the function of this protein?
Probable disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At5g04720.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: FAPR_ECOLX
Sequence: MKLKNIHLYNYVVIYTKNCEIYINKGNEQVYIPPRMVAIFEKNISFNIETIRKGDGVLYESFDMKHELLTSLRRVIEPSVKFAAESYTNKRSFKERIFKVKSCSIVIDLFKRLKDNGSPEFTAIYELAFLVSKCENPSMFAISLFSSVAVTFSERIVTLLFSDLTRKWKLSDIAEEMHISEISVRKRLEQECLNFNQLILDVRMNQAAKFIIRSDHQIGMIASLVGYTSVSYFIKTFKEYYGVTPKKFEIGIKENLRCNR
What is the function of this protein?
Positive regulator of the expression of the 987P operon for the fimbrial protein in enterotoxygenic E. coli.
What are the official names of this protein?
987P fimbrial operon positive regulatory protein FapR.
Protein: GLYA_STRMK
Sequence: MFPRDVRIESYDPELAKAIAAETQRQEDHVELIASENYTSPAVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDIAEQLAIDRLKQLFGADYANVQPHSGSQANQAVYFALLQPGDTILGMSLAHGGHLTHGAKVNASGKLFNAVQYGVNDQGLIDYDEVERLALEHKPKMVVAGFSAYSQVIDWARFRAIADKVGAYLFVDMAHVAGLVAAGVYPSPLEHAHVVTSTTHKTLRGPRGGIIVAKGADEDLVKKLQSIVFPGIQGGPLMHVIAGKAVAFKEALEPGFKAYQQQVVKNAQAMANTLIERGYKIVSGGTQNHLMLVDMIGKDVSGKDAEAALGKAHITVNKNSVPNDPRSPFVTSGLRLGTPAVTTRGYVEQDCVDLANWIADVLDAPNDDAVIARVRDAVSAQCRKYPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_MSTV
Sequence: MATNKPANLNDLQKAINDISKDALKYLTDNKASVTTFHDQIGYAGYDAATLIGILKDKGGATLAQDVVKMIVMRYVRGTGFVKDVTKKTKATAGSEEAAALVARYGLVSSVGSNANAITLGRVAQLFPNVSFEVTKQFTGLKMAIDSSDLSMSGTDSLLWDFVPQYITLDSSSAPYCTTKSVAHILFSIHVIHAFLVTKKTMPEAKKKERGLLKDIDIIKYTTGLLVITCQSKNLNEAKKKSGRTKVCEPYCVNEKFKESFLALLASFGKNVVCSYGTQVKQFLAEQCSLMKTIVDNSSKTQDEMKALIIEFFEEE
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC), and serves as template for viral transcription and replication (By similarity).
What are the official names of this protein?
Nucleoprotein, Coat protein, CP, Nucleocapsid protein, Protein N, Protein pc3.
What is the protein family that this protein belongs to?
Belongs to the tenuiviruses nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PCCB_SACEN
Sequence: MSSATEPVGVPPAEAPDIHTTAGKLADLYRRNHEAVHAGSERAVAKQHAKGKRTARERIDMLLDEGSFVELDEHARHRSTNFGMDADRPYGDGVVTGWGTVDGRRVCVFSQDFTVFGGSLGEVFGEKIVKVMDLAMKTGCPLVGINDSGGARIQEGVAALGLYAEIFKRNTHASGVIPQISLIMGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVSFEDLGGARTHNERSGNAHYLATDEDDAISYVKELLSFLPSNNLSSSPVFPGAEVEEGSVADGVGDADLELDALVPDSPNQPYDMREVITRLVDEGEFLEVSALFAPNMLCGFGRIEGASVGVVANQPMQLAGTLDIDASEKAARFVRFCDAFNIPVLTLVDVPGFLPGTGQEWNGIIRRGAKLLYAYAEATVPLVTVITRKAYGGAYDVMGSKHLGADINLAWPTAQIAVMGAQGAANILYRRQLAEAAERGEDVEALRARLQQEYEDTLCNPYVAAERGYVDSVIPPSHTRGHVARALRMLADKREALPAKKHGNIPL
What are the official names of this protein?
Propionyl-CoA carboxylase beta chain, PCCase, Propanoyl-CoA:carbon dioxide ligase.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: FABI_SALTY
Sequence: MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSSIVLPCDVAEDASIDAMFAELGNVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKVAHDISSYSFVAMAKACRTMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: EFG1_BORBU
Sequence: MDYNKLRNIGISAHIDSGKTTLTERILFYCNKIHAIHEVKGKDGVGATMDSMELERERGITIASAATHVEWKDFPINIIDTPGHVDFTIEVERSLRVLDGAILVLDSVAGVQSQSITVDRQLKRYSVPRLAFVNKCDKTGANPYNVKDQLRSKLDLNSVLMQIPIGLEDKHIGVIDLVLMKAYYFEGKDGTEIIEKEIPSDLLEEAKSKREIMLDTLADFNDELMELHMEGKEVPTEIIYNATRTGTLALKLCPVFMGSAYKNKGVQLLLDAVTRFLPSPHDIKNTALDLNNNEKEIDLKIDNELPTVALAFKLEDGQYGQLTYVRIYQGILKKGQELINSRTSKKFKVGRLIRMHANNTEDIEFGGSGDIVALFGIECASGDTFCDPSINYSMTSMFIPDPVISLSVKPKDKKSADNMAKALGRFTKEDPTFKTYVDIESNETIIQGMGELHLEVYIERMKREFKAEVETGMPQVAYRETITRKAEFNYTHKKQSGGAGQFGRVAGFMEPLDKEGETYEFVNLIKGGVIPTEYIPSCDKGFQKAMERGTLIGFPIVDIKITINDGQYHIVDSSDIAFQLAAIGAFREAYEKAKPTILEPIMKVTLEGPTEFQGNMFGLLNQRRGIITGSLEDGSFSKVEAEVPLSEMFGFSTVLRSSTQGKAEFSMEFLRYGKVPSTIFDELRKKFNDQNKS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOC1_LODEL
Sequence: MAPRQSQTAKRNKTQNKTRENESEVFLDSAARNLLENQPKLAAKSKVKKLSKLQVKKQQAKIRLYGAKNGKEYREEQLSIPDLNKAIVPGVKAKRGKKGKKFVDDNDSLTLNRLVKSINDKYDQVNESKLEKSRRLEEIRELKRQEMERKEQMKKDKLDGKKDELRSKASVARAARRKNAKARKADEVDEGENTVPKKKKVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein LOC1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PYRH_THEON
Sequence: MRIVFDIGGSVLVPDDPDIDFIKAIAYELTKISEDHEVAVVVGGGKVARKYIKAAKTFTPNETFKDYIGIHITRANAMLLIAALGEKAYPFVVQDFRKAWEVIQLKKIPIMGGTHPGHTTDAVAALLAEYLQADLLIVVTNVDGVYDSDPRKNPNAKKLDRITVDQLVDIAMEGESKAGGSGVVDALAAKFIQRGKIRTYIVGKKDAYSLFDVIKGKHSGTVVEP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_EEVVP
Sequence: MFPFQPMYPMQPMPYRNPFAAPRRPWFPRTDPFLAMQVQELTRSMANLTFKQRRDAPPEGPPAKKPKREAPQKQKGGGQGKKKKNQGKKKAKTGPPNPKAQSGNKKKPNKKPGKRQRMVMKLESDKTFPIMLEGKINGYACVVGGKLFRPMHVEGKIDNDVLAALKTKKASKYDLEYADVPQNMRADTFKYTHEKPQGYYSWHHGAVQYENGRFTVPKGVGAKGDSGRPILDNQGRVVAIVLGGVNEGSRTALSVVMWNEKGVTVKYTPENCEQWSLVTTMCLLANVTFPCAEPPICYDRKPAETLAMLSVNVDNPGYDELLEAAVKCPGRKRRSTEELFKEYKLTRPYMARCIRCAVGSCHSPIAIEAVKSDGHDGYVRLQTSSQYGLDSSGNLKGRTMRYDMHGTIEEIPLHQVSLHTSRPCHIVDGHGYFLLARCPAGDSITMEFKKGSVTHSCSVPYEVKFNPVGRELYTHPPEHGAEQACQVYAHDAQNRGAYVEMHLPGSEVDSSLISLSGSSVTVTPPVGTSALVKCKCGGTKISETINKAKQFSQCTKKEQCRAYRLQNDKWVYNSDKLPKAAGATLKGKLHVPFLLADGKCTVPLAPEPMITFGFRSVSLKLHPKNPTYLTTRQLADEPHYTHELISEPAVRNFTVTEKGWEFVWGNHPPKRFWAQETAPGNPHGLPHEVITHYYHRYPMSTILGLSICAAIVTVSVAASTWLFCKSRVSCLTPYRLTPNARMPLCLAVLCCARTARAETTWESLDHLWNNNQQMFWIQLLIPLAALIVVTRLLKCVCCVVPFLVVAGAAGAGAYEHATTMPSQAGISYNTIVNRAGYAPLPISITPTKIKLIPTVNLEYVTCHYKTGMDSPAIKCCGSQECTPTNRPDEQCKVFTGVYPFMWGGAYCFCDTENTQVSKAYVMKSDDCLADHAEAYKAHTASVQAFLNITVGEHSIVTTVYVNGETPVNFNGVKLTAGPLSTAWTPFDRKIVQYAGEIYNYDFPEYGAGQPGAFGDIQSRTVSSSDLYANTNLVLQRPKAGAIHVPYTQAPSGFEQWKKDKAPSLKFTAPFGCEIYTNPIRAENCAVGSIPLAFDIPDALFTRVSETPTLSAAECTLNECVYSSDFGGIATVKYSASKSGKCAVHVPSGTATLKEAAVELTEQGSATIHFSTANIHPEFRLQICTSYVTCKGDCHPPKDHIVTHPQYHAQTFTAAVSKTAWTWLTSLLGGSAVIIIIGLVLATIVAMYVLTNQKHN
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to cell receptor LDLRAD3 and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: TRPF_PARDP
Sequence: MAVSVKICGLTEAAGLAAAVDAGARYVGFVFFPKSPRHVTPGTAAELAAQVPLGVAKVGLFVNPDDAALDAVLAHVPLDVIQLHGAETPARVAEVKARTGLPVMKAVGVADPQDLDALWDYGLVADMLLIDAKPPKDAVLPGGNGLAFDWRLLAGRQILKPWLLAGGLTPENVHEAIRLTRAPGVDVSSGVESAPGVKDPDRIRSFIARATAPIL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: OR5K4_HUMAN
Sequence: MARENHSLAAEFILIGFTNYPELKTLLFVVFSAIYLVTMVGNLGLVALIYVERRLLTPMYIFLGNLALMDSCCSCAVTPKMLENFFSEDRIISLYECMAQFYFLCLAETTDCFLLATMAYDRYVAICHPLQYHTMMSKTLCIRMTTGAFKAGNLHSMIHVGLLLRLTFCRSNKIHHFFCDILPLYRLSCTDPSINELMIYIFSIPIQIFTIATVLISYLCILLTVFKMKSKEGRGKAFSTCASHFLSVSIFYICLLMYIGPSEEGDKDTPVAIFYAIVIPLLNPFIYSLRNKEVINVLKKIMRNYNILKQTCSIANLFLIY
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5K4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZRG8_CANGA
Sequence: MRSFIKSHRKSNSLESDSDIDFKQLKRKNASTSQLSPPRYNTDYYDPVTSSPKTPTHSHTTSDSLPQKHSPGFESLHRLFNNKLFKKASNSSLNSYLANTDSQSRRSSKDQDPLAPSFHVLKTSSNPASQDSELPVIKGVITHTWGNHSKHNDPHVIVLNDPKTSFETLRSSDLEPPPRLTSKTTRSSVSSERSWSTRDHSMSPPLTSINQDIDIPEDMATRSKNTLINKKKMENRQARIHSNDDLIAMRKNSSDTLPQTAEFFASDKLPGDSTPILEIPESPPPVITLEKYNSSLSDAKELSRSKNVRSNRTSVVSMTQSEESRWSNHLMVNSNHNQNKLRDSDDSDYSNAIDEEDDDDADDDDEASQFSFEYSNLSGRTPSVKYYSKPEPKQMVYIDDLYDDEDFDEDMNYYDENEVSEFLQEEMASNKNNINTDTSVLKDLSSPSINDHSNEKPIYKPTIQMRVNKPKVHRYNDLFALSDEDDPSFNDDDEFDEDEEEGGDDNDEEDEIDEEYDQKVSDECGQSIELQSDDIHSDYGVEYYNDFGGDLNLQNDVQKHHINKEQQYISDEEFDDAITDFNMAKHIIEEEVVLDKAEALRYQKDAEPVQSKTSEDVVNYVDEDSNLRINEKLEKGDVTYQKPTLLTEVKNKQFQKKPVASFADIFNLESDSEEDINNEDGLTGLSDVGLDEDDAVSSPILQSPFESQSLAEGLVSPVICTPGKPNIINKQIIPTIKCEPSSPQEKTIENNKSHTASNFKEYGLNHPLPPPARSQALKFHDLNSELDSELPALMSNLYFIDETEEDAYNELNDVTRDEDEYLDEINTVPEDFNFSDTENDNNAAKRMLRRSNKGSFRSTYSFTDKPQGVTTESSPIKNKLEVNNKTVTFFSSPGWSKSPGSEIGMQRSKSPVKPSSGYRPFGQGSKQFPITPSHEPNYSIEEDRIASTDEILESRTPPTTYMAPSPAFIPNYSLSPIQEASSSVTNSPKR
What is the function of this protein?
Involved in maintenance of polarized growth and daughter-cell-specific transcription.
What are the official names of this protein?
Zinc-regulated protein 8.
What is the protein family that this protein belongs to?
Belongs to the ZRG8 family.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Bud tip.
Protein: CSPA_MYCBO
Sequence: MPQGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGTGFRTLEENQKVEFEIGHSPKGPQATGVRSL
What are the official names of this protein?
Probable cold shock protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SALPB
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLAREALGTNWLKLEIHPDARWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCSAVMPLGAPIGSNQGLETKAMLEIIIQQSTVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVMMATAFRLAVEAGVLARQAVPGSKSSQASATSPLTGFLEALA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB_BURL3
Sequence: MRQPLLKLAAVTRRFPAGDKDVVVLNNVNLSIHAGEIVAIVGASGSGKSTLMNILGCLDHPSEGTYTVGGRDTHMLDSDELAQLRREHFGFVFQRYHLLPHVDAVANLEMPAIYAGTPRAERHARARELLARLGLADRAHHRPGQLSGGQQQRVSIARALMNGGQVILADEPTGALDTKSGQDVIRILHELNALGHTIVIVTHDKAVARHAKRIIEISDGEIVADRPNRHYAEALAEAGVDAAEAAEASEAAVGESPTRNRHDTPAPPAAVDTDPHVDTGTRTRRFAAGSGRFAEACRMAWIALVSHRLRTLLTMLGIIIGITSVVSIVAIGEGAKRYMLDEIGSIGTNTINIYPGTDWGDSRADAIQTLVPADVAALTEQPYVDSATPETSRTLLLRYRNVDVNALVSGVGDRFFQARGMRFALGVAFDEDAVRRQVQVAVIDQNTRRKLFGATRNPIGEVILVDNVPCVVIGVTADKKSAFGSVKSLNVWVPYTTASGRLFGQRYLDSITVRVRDGQPSAAAEKSLEKLMTQRHGRKDFFTYNMDSVVKTVEKTGQSLTLLLSLIAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARQSDILQQFLVEAVLVCLLGGTIGIALSFGLGALFSMFVAQWKMVFSAGAIVTAFVCSTLTGVIFGFMPARNASRLDPIDALARD
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: D19L4_MOUSE
Sequence: MAKEEGTSVEPRQRKKQRTSGSQEAKAEKIRRTPAPERAPKYVSFQRFAKIVIGCLAAVISGMMHVFYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTISLKTINAMQQMSLYPELIASVLYQATGSNEVIEPVYFYIGIVFGLQGMYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNLNTYAERFCYLLLSTSTYTFMMVWEYSHYVLFLQAVSLLLLDIFSVEQSDKVYEVYKVYIFSLFLGYLLQFENPALLVSPLLSLVGAFMLVKCLQLNGKKGTFVAKVIKVFEFYLLCTLPVTLNLIVKMFVPHKENEHVLKFLEVKFGLNMTKNFTLNWLLCQESLQAPSQDFFFRLTQSSLLPFYVLVLIICLLSMTQVFFRRMSGKSKKETVTLEDGRIGERPEIIYHVIHTLLLGSLAMLMEGLKFIWTPYVCMLAAFGVCSPELWMTLLKWLRLRTVHPMLLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWTVTSLPLYSDDDLLQRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNELGTTRGCRVKDLLDIANGHVVFEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKVNTVISFQS
What is the function of this protein?
Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
What are the official names of this protein?
Probable C-mannosyltransferase DPY19L4, Dpy-19-like protein 4, Protein dpy-19 homolog 4.
What is the protein family that this protein belongs to?
Belongs to the dpy-19 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y084_ATV
Sequence: MITVNCIKLKQAFEQAKILKNDPYDFALAMTHFYLSNEGLETPTGYSVPSSELKELIKKNELLIHYILDEGEDFMEACEKVHGS
What are the official names of this protein?
Uncharacterized protein ORF84.
Protein: RHOL_DROME
Sequence: MTANITKSPRPLKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNSEKFVTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAVERKPKTTSKQSCKIL
What is the function of this protein?
Essential for the maturation of hemocytes.
What are the official names of this protein?
Ras-like GTP-binding protein RhoL.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GS39_BACSU
Sequence: MANYPKELPAQTQSRQPGIESEMNPSPVYEYEDYKGADKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQEGVKCLLIAGDVGEEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTFKTNFYSQFYLTKKAIDYLKPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQALVKDGIRVNAVAPGPIWTPLIPATFPEETVAQFGQDTPMGRPGQPVEHVGCYVLLASDESSYMTGQTLHVNGGNFVTT
What are the official names of this protein?
General stress protein 39, GSP39.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LRGB_BACSU
Sequence: MESTMSPYFGIVVSLAAFGIGTFLFKKTKGFFLFTPLFVAMVLGIAFLKIGGFSYADYNNGGEIIKFFLEPATIAFAIPLYKQRDKLKKYWWQIMASIIAGSICSVTIVYLLAKGIHLDSAVMKSMLPQAATTAIALPLSKGIGGISDITAFAVIFNAVIVYALGALFLKVFKVKNPISKGLALGTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVLVIPVFVQLIGG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEPA_ASPNC
Sequence: MVVFSKTAALVLGLSSAVSAAPAPTRKGFTINQIARPANKTRTINLPGMYARSLAKFGGTVPQSVKEAASKGSAVTTPQNNDEEYLTPVTVGKSTLHLDFDTGSADLWVFSDELPSSEQTGHDLYTPSSSATKLSGYTWDISYGDGSSASGDVYRDTVTVGGVTTNKQAVEAASKISSEFVQNTANDGLLGLAFSSINTVQPKAQTTFFDTVKSQLDSPLFAVQLKHDAPGVYDFGYIDDSKYTGSITYTDADSSQGYWGFSTDGYSIGDGSSSSSGFSAIADTGTTLILLDDEIVSAYYEQVSGAQESEEAGGYVFSCSTNPPDFTVVIGDYKAVVPGKYINYAPISTGSSTCFGGIQSNSGLGLSILGDVFLKSQYVVFNSEGPKLGFAAQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A.
What are the official names of this protein?
Aspergillopepsin-1, Aspartic protease pepA, Aspergillopepsin I, Aspergillopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_LACDB
Sequence: MNKPLFIALDYDDQEKMWLFLNQLKDKQGLHVKLGMEMFYQYGPEIVRDLSAKGYQIFLDLKLHDIPNTVKRTAHQLAALGVYCTTVHALGGKQMIQAAKEGLIEGTPAGKPVPKLLAVTELTSISEEVLKNEQHCSLNLADEVKSLAHQAQEAEADGIICSPLEVKAMKSEFSDDFMFVTPGIRPKSYQKDDQARVATPGQARENGSTAIVVGRPITQAADPQKAYEEILKDWSKNDAK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: GEMI2_DROME
Sequence: MQHEPEDQTFQLQALEICEPDSSFDPQKPPESGEEYLMHMFYERKRCPAVVTKRSSKIRNNTGNTTLEMLDNPELPPFKCLLPTPEWRDEQVKSFQAARSQVLVLRKELANNNYDQSGEPPLTSDQEKWKEFCRNQQPLLSTLLHLTQNDLELLLEMLSKWLQDPNTTVDLLHDVWLARWLYATLVCLHLPLEPHVFSTLRYIARTCIHLRNQLKEDEVQRAAPYNLLLTLTVQVFAQNDFKDYI
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (PubMed:18621711, PubMed:23333303).  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG (5Sm) are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity).  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A (By similarity).  Binding of snRNA inside 5Sm ultimately triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity).  Within the SMN complex, GEMIN2 constrains the conformation of 5Sm, thereby promoting 5Sm binding to snRNA containing the snRNP code (a nonameric Sm site and a 3'-adjacent stem-loop), thus preventing progression of assembly until a cognate substrate is bound (By similarity).
What are the official names of this protein?
Protein Gemin2.
What is the protein family that this protein belongs to?
Belongs to the gemin-2 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of U bodies.
Protein: ASSY_SALHS
Sequence: MTTILKHLPAGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNVELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDESVKIPAEVVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHSHGRQLGKLLYQGRWFDSQALMLRDGLQRWVASQITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKAGLLTASSATGLPQVENLENKGK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.