PharMolix/UniProtQA huggingface dataset:
Protein: URE2_DINSH
Sequence: MIPGEIMAAPGDITLNAGATPLTLTVSNTGDRPVQVGSHYHFAETNAGLSFDRDAARGMRLDIAAGTAVRFEPGQTRDITLVPFGGARKIYGFNQGIMGAL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_CHLTA
Sequence: MDRSPLFLIIMGAPGSGKGTQSKLLASQLSLLHISSGDLLRDAVSKDTPLSQEIKSYLDQGKLLPDTLVWKLVHEKLDEFQQDTLLRRLSFLSRSENSAILDGFPRTVTQAKLLHEFLSSYFPNYKVILLDISDEEVLNRLTSRYICPACQGIYNEQQGFSSCPKCSVELIRRSDDTLEVILDRIQTYKQETQPVLDYYTEKQKLITIDANAPTQQVFQSILDSLSASLVYQERDCCNCDCDDED
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_PELUB
Sequence: MICSICKKGETSVVDSRPTEDGTAIRRRRLCVCGARFTTFERVQFREIMVVKKNGRKSSFDRDKLSKSIYIALKKRPIDTETAEKFISRTSRALEELGQSEISSNTIGTMVMEGLKDLDPVAYVRFASVYRNFREEKDFVQFVDKLDVYKKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RLMD_ALTMD
Sequence: MANLFKQSRAKQKNKTTPSQTQTSTKGSARANAQVAGLRFKKSKQSKEHNTAQDANNNAITIQELDWMGQGVARGATMYFVEGALPGETCDIEVVSSKKKVVSAKTISIQGPSELRQPPFCPVFEACGGCQLQHIDADAALAYRDNALKIMMERQLSIGSGVWQAPLVGPRPQYRRKARLAIDARNPDNIKLGFREANSNKVVNLDTCPILVNPLSTAIGPLRNALEGYDSARHIGHISLIAGDNRAQVVIKHTKALEDALIETVDAFAKALGLDVVLENKQGRLRSVGEAQGLIMHTVDGCSISPSANDFIQINKVVNEKMINQALVWLDPRPNERIADWFSGLGNFTLPIAKKGALVQAIEGVAEMVLRAKDNAQQQGIENVEWLHLDLANKANVEASLQQGFDKVLLDPSREGALTVCHALVKALPKTIVYVSCNPSTFSRDAKVLINGGYEMEKAGVAEMFPFTHHMEMMALFTQRQQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: MYO1F_HUMAN
Sequence: MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Unconventional myosin-If, Myosin-Ie.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: NANE_MYCMS
Sequence: MNLIDQIKNTLIISCQAVDDEPLNDSYVLSKMCYALVLGGAKVLRLSQVEHIKKIKEVVNVPIIGLIKKHYDNSEVFITPTIKEVDQLVDLKVDIIALDATLRKRPDQDLTNLIKTIKTKYPNQLLMADCSNINDAINAQNLGFDLISTTLRGYTKDTLNHNNIENDYQFLKDLKKVITKPIIAEGGIWTPQQAKEILNLGIHSIVVGSAITRLHLIVKYWNDNLK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: CHI1_RHINI
Sequence: MISCNILGITIAAFITSTLAAYSSNGVNVMYYWGQNSAGGSNTQGSLVSYCQSGQVDVIILSFLNKFNMGGLPEINLASACEQTFFPNTNLLHCPTVGSDIKTCQSNGVKVLLSLGGAAGSYGFSSDSEGQTFAETIWNLFGGGTSDTRPFDDAVIDGIDLDIEGGSSTGYAAFVTALRSKGHFLIGAAPQCPFPDAILGSVIDAVGLDFVNVQFYNNVCSVASGSSFNFDVWNDWAKNKSPNKNIKVMLTVPGSSTAAGSGYASIAELGPIVSSVISQYSSFGGVSVWDASQAWNNNGFHSELYSIVHGSSAALGQAARKTPFPNTSSITTTSLATASSALFPLLYAGRSCSSQSKVSCTSTGSYTICNYGKWVTAPCPPGVICLSSAQSNNTDLTVSAQFFITSFAGGSFKAIINARRTTLTPFEKMKTIEFTVPDHVRLSQCNLGKIEQVGRSVRIRLKDHPNMAFVLNLSGNVSSDAFVAPDPSSWRFS
What are the official names of this protein?
Chitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
Protein: HIS5B_ARATH
Sequence: MELLSSSPAQLLRPNLSSRALLPPRTSIASSHPPPPRFLVMNSQSQHRPSISCASPPPGDNGFPAITTASPIESARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGGTIPSSKGVLSRS
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, IGPD 2, Protein HISTIDINE BIOSYNTHESIS 5B.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PXPA_RHOP2
Sequence: MKIDLNCDLGEGFGAWSMGDDAAMMRIATSVNVACGFHAGDPDIMHKTVAMAKAHGVAIGAHPGFRDLHGFGRRPVPGITAAEIENLVAYQIGALQAVASLAGHKVTHVKAHGALSNVACQDDMTARAIAAAIKAVDPKLIFVVLANSKLVDAGEAAGLAMVHEVFADRAYEDDGNLVSRRKPGAVLHDPAVIAERVLRMAQDGAVVSMTGKVIKMRTDTVCIHGDTAGAVDIARGVRTALEANGITVAPFARS
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: QADG_PARDE
Sequence: MNALVGCTTSFDPGWEVDAFGAVSNLCQPMEADLYGCADPCWWPAQVADTLNTYPNWSAGADDVMQDWRKLQSVFPETKGSS
What is the function of this protein?
Catalyzes the oxidative deamination of a wide range of primary aliphatic and aromatic amines (PubMed:10346915).  The physiological electron acceptor is the constitutive cytochrome c550 (PubMed:11168384).
What are the official names of this protein?
Quinohemoprotein amine dehydrogenase subunit gamma, QH-AmDH, Quinohemoprotein amine dehydrogenase 9 kDa subunit, Quinohemoprotein amine dehydrogenase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the quinohemoprotein amine dehydrogenase subunit gamma family.
What are the subcellular locations of this protein?
Periplasm. Note=Is probably co-translocated into the periplasm when associated with the alpha and/or beta subunit, which contain both a signal peptide.
Protein: ARGA_PSEPF
Sequence: MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGSRPQIETRLAARGLTPHYHHGMRITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSRLRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLLDERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAELLDAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLLDLISPLEEQGILVRRSREVLEREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNPEYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRERGFEPSSVERLPAARASLYNYQRNSKIFEKSL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIP2_NICBE
Sequence: MASSCCLHAILLCSLLFITSTTAQSETSFRPKGLILPITKDALTLQYLTQIQQRTPLVPVSLTLDLGGQFLWVDCDQGYVSSTYRPARCRSAQCSLAGAGSGCGQCFSPPKPGCNNNTCGLLPDNTITRTATSGELASDTVQVQSSNGKNPGRHVSDKDFLFVCGSTFLLEGLASGVKGMAGLGRTRISLPSQFSAEFSFPRKFAVCLSSSTNSKGVVLFGDGPYTFLPNREFANNDFSYTPLFINPVSTASAFSSREPSSEYFIGVKSIKINEKVVPINTTLLSIDNQGVGGTKISTVNPYTILETSIYNAVTNFFVKELVNITRVASVAPFRACFDSRNIASTRVGPAVPSIDLVLQNENVFWRIFGANSMVQVSENVLCLGFVDGGVSPRTSIVVGGYTIEDNLLQFDLARSRLGFTSSILFRQTTCANFNFTSIA
What is the function of this protein?
(Microbial infection) Possesses stronger binding affinity with XLP1, a truncated paralog of P. parasitica XEG1 which has no enzyme activity.  Is impaired in its inhibitor activity towards the P. parasitica xyloglucanase XEG1 when hijacked by XLP1 binding.
What are the official names of this protein?
Probable aspartic proteinase GIP2, Glucanase inhibitor protein 2, NbGIP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PROB_BRUA1
Sequence: MLKKLKDYRRIVVKIGSALLVDRATGLKRKWLESLGQDIAALQHAGVEVLVVSSGAIALGRTVLGLPKKALKLEESQAAAAAGQIALAKAYADVLGGHGIKSGQILVTLSDTEERRRYLNARATIETLLKLKAVPIINENDTVATTEIRYGDNDRLAARVATMMGADLLILLSDIDGLYTAPPHKNPDAQFLPFVETITPQIEAMAGAAASELSRGGMKTKLDAGKIANAAGTAMIITSGTRFGPLSAIDRGERATLFEAAHAPVNAWKTWISGNLEPAGRLTVDAGAVKALKSGKSLLPAGVKEVDGDFERGDTVAVMNEDGREIARGLIAYDAADARKVAGHKSDEISAILGYDARAAMIHRNDLVVRAASDAKAA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIB_SALTI
Sequence: MKRTKSIHHASFRKSWSARHLTPVALAVTAVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDAAGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSAAGTSTRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: RS6_POLSJ
Sequence: MRHYEIVLLIHPDQSEQVPAMLERYKGMITAGGGKVHRVEDWGRRQLVYLIQKLAKAHYLCINIEASQAVMEEIEHAFKFNDAVLRHLTVVKKKAETGPSLMMRNVEREEARKAQQQEYAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y4256_RHILO
Sequence: MSEDLPILSPIEARVLGCLIEKKELTPDVYPLTLNAALAAANQKTARDPVMALEQTEVHRALKLLEQKGLVRQMFGSRVERYEHQMAQRFSLTTPQTALIGLLLLRGPQTAHELLARAERMARFSSIEDLRGELDMLIGRRPPLVQEIPRGPGQREDRYVHLLAGPVDVAALSAQRSAPAMPHSDLEARLEALEQEVAALRARLDALGG
What are the official names of this protein?
UPF0502 protein mll4256.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: TORD_VIBCM
Sequence: MMQELKILNEKRAEIYWWLSSLFFKELSEQDIARYHSAEVRTFLSGLADEQSLNREVKHLVEALNRLQDRQDAQLELAADFCDLFLKSDRDSALPYASVYADQGLLNGKPAQQMRELLSAHGVKVEQNLNEPEDHLAIQLDFLAHLAISANQIEHSAQLSLALQAQSDFISQHLLTWLPAFAERCTQFDAFGLYSAAARLALAFIQQDKHCLDELIQETH
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_BACAN
Sequence: MIKVVFMGTPDFSVPVLRRLIEDGYDVIGVVTQPDRPVGRKKVLTPTPVKVEAEKHGIPVLQPLRIREKDEYEKVLALEPDLIVTAAFGQIVPNEILEAPKYGCINVHASLLPELRGGAPIHYAIMEGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKTVPLLIQGKLEPIKQNEEEVTFAYNIKREQEKIDWTKTGEEVYNHIRGLNPWPVAYTTLAGQVVKVWWGEKVPVTKSAEAGTIVAIEEDGFVVATGNETGVKITELQPSGKKRMSCSQFLRGTKPEIGTKLGENA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RR9_EUGLO
Sequence: MIFKFFEAIGKRKCSIAKISLFSTVKYNCGVININGKHAYEYLQKNCNPFDFLKIKNYNVCIYVKGGGLIGQAEAIKLAISRALKSFLRKKKIKKLKDFGFLTRNSSCKERRKYGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid.
Protein: CH602_BURVG
Sequence: MTAKDVKFRDGARSQIVKGVNVLADAVKVTLGPKGRNVVIERSFGAPVITKDGVSVAKEIELKDRFENMGAQIVKQVASKTADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGIDKAVGVVLEELRTLSRPISTHKEIAQVGAISANADDAIGKIIADAMEKVGKEGVITVEDGKSLDNELDVVEGMQFDRGYISPYFINDPEKQAAYLDDALILLHDKKISNIRDLLPILEAASKAGKPLLIVAEDVEAEALATLVVNAMRGILKVAAVKAPGFGDRRKAMLEDIAILTGATVISEETGKQLDKATLDDLGSAKRVEVRKDDTIIIDGAGDAARIDARVKSIRVQIDEATSDYDREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDALHATRAAVEEGIVPGGGVALLRARAALTDLKGANGDQDAGIRIVLRALEAPLRVIASNAGDEPSVVIAKVLEGSGNFGYNAATGEYGDLVEAGVVDPTKVTRTALQNAASIAGLVLTTDATVADAPKDERAEAAPSPELGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS3L_XENLA
Sequence: MAESEGSNTENGKVGAVKSENLDRGVAAIKNQFLTTKEKFHAFIDADGKDVTEKETCSELSLNDAENTTRTENAAEPEAKRIKLDDGSSEGQDQPPKTAENKQEKKRARGQNKSRPHMKHSQFEENKLCPSVTQECASKCFFGDKCKFSHDVAKYVSQKPEDIRPNCHLYETFGKCIYGVTCRFAKSHLGEDFKNIINEELMKEWEGKVLVKNSLDKSLKEQLRKKKVVFEKSDKYLKLCFKSGDSSKMKNPVVKEDSAVQVTQKDSPITTVGAVTDEDVIKLRPCEKKTIDFRNKLYLAPLTTCGNLPFRRICKRLGADITCGEMAMCTNLLQGQPSEWALLKRHHSEDIFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCGLMNRTNKFEQIVKGMNSVLDVPLTVKIRTGVQEKVNIAHKLIPNLRDWGVSLVTLHGRSREQRYTKLANWEYIDQCAKIASPVPLFGNGDIISYEDANRALQTGVAGVMLARGALFKPWLFTEIKEQRHWDISSTERFDILKDFTNYGLEHWGSDCQGVEKTRKFMLEWLSFLCRYIPVGLLEHVPQKINERPPYYMGRDYLETLMASQNVTDWIKISEMLLGPVPPNFTFLPKHKANSYK
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs).  Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs.  Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation.
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like, mRNA-dihydrouridine synthase DUS3L, tRNA-dihydrouridine synthase 3-like.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
Protein: THIG_COXB1
Sequence: MWAIGGVQLNSRLLLGTAQYPSPQLMSDAVKAAGVEIITVSLRRQLSPQKENYFWDLLRSLPCHLLPNTAGCSSVKEAVNTARAARELFNTHWIKLEIIGDEYTLQPNPFELVNAATILVKEGFEVFPYCTEDLILCQRLVDAGCRVLMPWAAPIGSGRGLMNTYALQLLRERFPKNILIIDAGLGRPSHAAQVMEMGFDAVLLNSAVALAMDPVVMAAGFAKAVEGGRLGYEGGMIKARNVAKATTPLIGKPFLIEKP
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_STRPS
Sequence: MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANKGLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWNLNAKPSLAFDTME
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_OENBI
Sequence: MTIALGKFTKDEKDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFEIARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ACPS_STAAR
Sequence: MIHGIGVDLIEIDRIKVLYSKQPKLVERILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKIDYEGFIVHVSISHTEHYAMSQVVLEKSAF
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_LARCA
Sequence: MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWRVVGYGAGFVLVLVVGGVVGGLVEFWHPGVITVDSGGMFSVRLDFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: Y1593_CALS8
Sequence: MAKNRFPGLGGGFNINQLQKQAKKIQEEIEKLQEELNQREIEATAGGGAVKVVINGKKEIKSIEISPEVVDPDDIETLQDLIVACVNEAIRKVEKMIEEEMQKVAGFGFTGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Csac_1593.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DMA_HUMAN
Sequence: MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWHDHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD
What is the function of this protein?
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides.  In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
What are the official names of this protein?
HLA class II histocompatibility antigen, DM alpha chain, MHC class II antigen DMA, Really interesting new gene 6 protein.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Protein: HPRT_METAR
Sequence: MLKILKESLKTAPIVKRGTYNYFIHPISDGVPVVKPELLRDVIACIVKNADLDVDKIVTIEAMGLPIGASLSQITDIPFIIIRKRKYELPGEIAVHQATGYSKGELYLNGICKGDRVLIVDDVISTGGTLAAVIKALEMAGAEIKDIVVVIQRGNGKKIIEDMGYNVQTLVTIDVDENGVQVLGCIDDECK
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_MYCVP
Sequence: MQPISPGAAVLVVGAGITGRAVLAALAPLGARATLTDDSPTALTASAQQRVEVLDPATAVDRIADFDLVVVSPGIPPTAPIPVAAAAAGIPVWGDVELAWHLDRSGRFGPPRQWLVVTGTNGKTTTTSMLYAMLQAGGRRAVLCGNIGDPVLSQLDRPADVLAVELSSFQLHWAPSLRPEAGAVLNVAEDHLDWHGSMAAYAGDKARALTGRVAVGGLDDAIAAGLLADAPAPVKVGFRLGDPGPGEFGVRDGVLIDNAFGRDLALADADTIPVAGPVGVLDALAAAALARAVDVPAAAIAEALATFHVGRHRAEVVAVADGITYVDDSKATNPHAAQASVSAFPRVVWVAGGLLKGASVDEMVEATKDRLVGVVLIGRDRAIVGNALSRHAPDVPVVELVTGEDSVVLEKDESGVTRVTRVIQTGDRTLADAVMTAAVDAARGLATSGDTVLLAPAGASFDQFTGYGHRGDAFAAAVRAAIR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.