PharMolix/UniProtQA huggingface dataset:
Protein: PETL_ORYSA
Sequence: MLTITSYFGFLLAALTLTLALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex (By similarity).
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SPIKE_CVBLY
Sequence: MFLILLISLPMALAVIGDLKCTTVSINDVDTGVPSVSTDTVDVTNGLGTYYVLDRVYLNTTLLLNGYYPTSGSTYRNMALKGTLLLSTLWFKPPFLSDFINGIFAKVKNTKVIKNGVMYSEFPAITIGSTFVNTSYSVVVQPHTTNLDNKLQGLLEISVCQYTMCEYPHTICHPNLGNRRIELWHWDTGVVSCLYKRNFTYDVNADYLYFHFYQEGGTFYAYFTDTGVVTKFLFNVYLGTVLSHYYVMPLTCNSAMTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGVYELNGYTVQPIADVYRRIPNLPDCNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPVGVFTDHDVVYAQHCFKAPTNFCPCKLDGSLCVGSGSGIDAGYKNSGIGTCPAGTNYLTCHNAAQCDCLCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCGGNPCTCQPQAFLGWSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGVCVNYDLYGITGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAFHANSSEPALLFRNIKCNYVFNNTLSRQLQPINYFDSYLGCVVNADNSTSSAVQTCDLTVGSGYCVDYSTKRRSRRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMEEFIQISSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSDCNKVSSRSAIEDLLFSKVKLSDVGFVEAYNNCTGGAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAATSASLFPPWSAAAGVPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDRGIAPKSGYFVNVNNTWMFTGSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLPDFKEELDQWFKNQTSVAPDLSLDYINVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGLAGVAMLVLLFFICCCTGCGTSCFKKCGGCCDDYTGHQELVIKTSHDD
What is the function of this protein?
Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers are transported to the host plasma membrane, where they may mediate cell- cell fusion.
Protein: RL35_STAAC
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RR9_STIHE
Sequence: MSQKLYILAKGIGRRKEAVAQVQLLAGSGQFIINGLPANLYLQEDPRSILAIDAPFKQLHVDHSADKDSLQTLDTIVKVQGGGKIGQANAIKLGVARALCEFNGEYRKSLKDSGFLTQDSRIKERRKYGLKKARKAPQYHKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AIM24_ASPTN
Sequence: MSQPWRRGVRALSWTRVLPPRARQGLSASQTRCVQIRAAPAEQPASVNGDHLPVVATPNSAQSSDARFDVIGAPYSMLSVSLSASQNLYTRRGTLVGLSGKADNVSSASPVTALVSVRSPVTSFAVVHLNGSVDWMVAQRRALLAWTGRSLSIRPTINTSLSIAHWGSSEVTGRGLLALVGTGQLYSVELKAGEQYIVHPSNVVAYTMSSNPPRPYRFKSTTLKFQVPGLKSLPRFIQDSKFIQDMSDTDTWKGTMKLFHKIRTWSRMTIWGDRLFLQFDGPTTILLQTRGPRINEILTTHEVNEIADSPRGLTIGPRKPSEDKKTAEEALQPTPDAPSRSVDDLIQEVEGSAQRIATITKEGKVFFEKAGQKN
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KTN1_VULVU
Sequence: MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPIPLNVVETSSSVRERKKKEKKHKPVLEEQVTKESDVSKIPGKKVEPVPVTKQPTPPSEAAASKKKPGQKKSKNGSDDQDKKVETLMAPSKKQESLPLQQETKQESGSGKKKVSSKKQKAENVLVDEPLIHATTYIPLMDNADSNPVLDKREVIDLIKPDQVEGIQKTGAKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIQDALKRSSKGELTALVHQLQEKDKLLAAVKEDAAVMKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVTKEESLQMQVQDILEQNEALKALIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANEHDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDQIRLLEEQLQCEISNKMEEFKILNDQNKALQLEVQKLQILVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEVLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQIQELQNLLKGKEEQMNTMKTVLEEKEKDLASRGKWLQDLQEENESLKTHIQEVAQHNLKEACSASRLEELETVLKEKENEMKRIETILKERENDLSSKIKLLQEVQDENKLFKSEIEQLKQCNYQQASSFPPHEELLKVISEREKEITGLQNELDSLKEAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKVERQQYVEAIELEAKEVLKKLFPKVSVPPNLNYGEWLRGFEKKPKECVAETSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEIERSTYVTEVRELKTQLNETLTKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSPEAESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE
What is the function of this protein?
Receptor for kinesin thus involved in kinesin-driven vesicle motility.
What are the official names of this protein?
Kinectin.
What is the protein family that this protein belongs to?
Belongs to the kinectin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Vesicle membrane protein anchored to the endoplasmic reticulum. In testis, localized at sperm surface.
Protein: ISPH_RIPO1
Sequence: MDTKAFKRSLQQSENYHRKGFGQTEAAMGVMNTEYQSSLIQQIRQNNYQWKQGNVTIHLAQAFGFCWGVERAVAMAYETRQHFPKESIWITNELIHHPSVNQRLEQMEIKFIEVINGQKDFSQIKSGDVVILPAFGASVSEMQLLNDRGCTIVDTTCPWVSKVWNSVEKHKKRHYTSIIHGKYRHEETVATSSFAGTYLVVLNLEQATYVCDYILKGGNKEEFLAKFKNAYSEGFDPDTDLEKVGIANQTTMLKSETEQIGKLFEGTMLKKYGPAVINDHFMSFNTICDATQERQDAMLELVKEKLDLMVVIGGFNSSNTTHLQEIPIYQGITSYHIDNATRIKPNNCIEHKPLGKDLEIKENWLPEGSIVVGITSGASTPDIIVEAVIEKIFSAKELEYQSN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RPOC_BURL3
Sequence: MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTAVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVHNEDTSEGAPPFVPKISLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGKETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETVYESGTLLDETAVEEIERLGIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGVTIKAGTQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEKQVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQQHPAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TYPH_HUMAN
Sequence: MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ
What is the function of this protein?
Catalyzes the reversible phosphorolysis of thymidine.  The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TP, Gliostatin, Platelet-derived endothelial cell growth factor, PD-ECGF, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: TXD16_HUMAN
Sequence: MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSVFLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLFDVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAAFVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNIHLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGKAGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDEDNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTAKEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQDIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDSFTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWLKKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQHEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
What are the official names of this protein?
Thioredoxin domain-containing protein 16.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum lumen.
Protein: GSA2_ANOFW
Sequence: MRSYERSKAAYAEAVKLMPGGVNSPVRAFKAVKMDPIFMARGKGSKIYDIDGNEYIDYVLSWGPLILGHANDQVVEALKRVAETGTSFGAPTLIENELAKLVMERMPSIEIIRMVSSGTEATMSALRLARGYTGRNKIVKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPETVAQHTITVPYNDLQSVRYAFEKFGEDIAAVIVEPVAGNMGVVPPEPGFLQGLRDVTNEYGALLIFDEVMTGFRVDYYSGQGYYGVTPDLTCLGKVIGGGLPVGAYGGRADIMEKIAPSGPIYQAGTLSGNPMAMTAGYETLRQLTPETYEAFKKKANRLAEGLSEAAKAYHIPHTINQAGSMIGMFFTNERVTNYETAKTSNLDLFARYYQEMANEGIFLPPSQFEGMFLSTAHTDEDIEKTIEAARRAFAKMSDCL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_LACCB
Sequence: MGRSLKKGPFADAHLLKKIEAQADNDKKTVIRTWSRRSTIFPSFIGYTIAVYDGRKHVPVFVSEDMVGHKLGEFVPTRTFRGHNTDDKKTTAR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PDXJ_XYLFT
Sequence: MSQRTRLSVNVNKIAVLRNSRGHGAPDVIRAASACIDAGAHGITVHPRPDARHIRHDDVIRLSALTRARGVEFNIEGNPFAEPRAGYCGLLALCRETRPHQVTLVPDGDQQITSDHGFDFAREGPGLRPLIDEIKQWGCRVSLFVDVNVTGLADAAIWGVDRIELYTGPYAEMHHAGCSDAVLREFATTARLAQDVGLGVNAGHDLSQTNLGVFLGAVPDVLEVSIGHALISEALYEGLIPTVRRYLDILDSVNPAVSMR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_SOLUE
Sequence: MPSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIPFEILNLPGGEDQKRLAPVEALAEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIPVLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAVLTDPAILDSLPEREYRAGLWEIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRILNFGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPIPSLAGIRAENLLARLVHDKKTVQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCC2A_PONAB
Sequence: MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in various processes, such as synaptic plasticity, neurotransmitter release and long-term potentiation.  Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity).  Regulates dendritic spine development.  Also regulates the migration of developing neurons.  Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (By similarity).  Phosphorylates the transcription factor ETS1 in response to calcium signaling, thereby decreasing ETS1 affinity for DNA (By similarity).  In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).  In response to interferon-beta (IFN-beta) stimulation, stimulates the JAK-STAT signaling pathway (By similarity).  Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Synapse. Postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Note=Postsynaptic lipid rafts.
Protein: RISB2_CAUVC
Sequence: MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAGHRPVGVRYDGYVALGVVIRGETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQALSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TRPA_SHEB5
Sequence: MSDTLTNTGRYQATFAKLKAEGRGAFVPFVTLGDPSPELSLKIIDTLVQNGADALELGFPFSDPLADGPVIQGANLRSLAAGTTPTACFELLAQVRAKYPELPIGLLLYANLVFANGIDAFYAKAQQAGVDSVLIADVPVEESAPFSEAAKAHGIAPIFIAPPNADSETLALVSASGEGYTYLLSRAGVTGTDTKAGVPVEEILSKLKTFNAPPPLLGFGIAEPAQVSAAIKAGAAGAISGSAVVKIIETHQHDEAKLLATLGDFTRAMKAAT
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: THRB_PONAB
Sequence: MAHVRGLQLPGCLALAALCTLVHSQHVFLAPQQALSLLQRVRRANSVFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHLNITQSGIQCQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSGVNLSPPSEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAMEEETGGGLDEDPDRAIEGRTATSEYQTFFDPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGATLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKVQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNCWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
What is the function of this protein?
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.  Functions in blood homeostasis, inflammation and wound healing (By similarity).
What are the official names of this protein?
Prothrombin, Coagulation factor II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ABRAL_XENTR
Sequence: MNVDHEVNLLVEEIRRLGSKGNDGKLSVKFGVLFSDDKCANLFEALVGTLKAAKKRKIVTYQGELLLQGVHDNVDIVLLQD
What are the official names of this protein?
Costars family protein ABRACL, ABRA C-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the costars family.
Protein: MQO_SERP5
Sequence: MRKILVLIFCLNLFGVTQQAAAEENKTVDVVLIGGGIMSATLGTYLHELEPNWSIDMYERMNGVAEESSNGWNNAGTGHSAFAEMNYTPEKKDGSIDISKAVVVNESFEISRQFWSYQVKNNVLKDPKSFINSVPHMSFVWGDDNVNFLRKRYAALQHSTLFRGMEYSEDANQIKQWAPLVMDGRDPKQKIAATRMPLGTDVNFGVITHQLVDTLTKNPNFKLNLSHEVRDIKRNDDNTWRVTVADLTRDGKETTVNAKFVFIGAGGASLTLLQKTGIPEAEGYGAFPVGGQFLVTTNPEIANQHLAKVYGLASVGSPPMSVPHLDTRMLDGKRVLLFGPFATFSGKFLKNGSLFDLLHSLSTSNLMPMTHVGLDNFDLVKYLVGQLMMNDDDRFAALKEYFPEAKQADWKLWTAGQRVQIIKKDDEKGGLLQFGTEVVSAKDGSIAALLGASPGASTAAPIMLHLMETVFKDKVATPEWQSKLKEIIPSYGHKLNGDIEMTNKIRGYTSSVLQLDYIEVKPETN
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PTH_SHEB9
Sequence: MSEIKLIVGLANPGAEYAHTRHNAGAWYVLELARICGVTLVADSKYFGLTARAVLHGKDVRLLIPTTYMNLSGKAVGALANFFRITPEEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIIAKLANDKNFYRLRLGIGHPGDKNQVSGYVLGKAPAKEQELIDAAIDEAVRSTEILFKQDMVKAMNRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_HISS2
Sequence: MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGKGLFVKELENALLNGEADIAVHSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDELPQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKLDQGDYDAIILASAGLIRLGLTERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQGGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGVSIAEQLLQQGADKILQAVYQS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YAEH_SALPA
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAKSVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILDDLRHLESVVANKISEIEADLDKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: EFTU_CAMJD
Sequence: MAKEKFSRNKPHVNIGTIGHVDHGKTTLTAAISAVLSRRGLAELKDYDNIDNAPEEKERGITIATSHIEYETDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKADMVDDAELLELVEMEIRELLSSYDFPGDDTPIISGSALKALEEAKAGQDGEWSAKIMDLMAAVDSYIPTPTRDTEKDFLMPIEDVFSISGRGTVVTGRIEKGVVKVGDTIEIVGIKDTQTTTVTGVEMFRKEMDQGEAGDNVGVLLRGTKKEEVIRGMVLAKPKSITPHTDFEAEVYILNKDEGGRHTPFFNNYRPQFYVRTTDVTGSIKLADGVEMVMPGENVRITVSLIAPVALEEGTRFAIREGGKTVGSGVVSKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFUT1_CRIGR
Sequence: MGAAAWAPPHLLLRVSLLLLLLLPLRGRLAGSWDLAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEEFMEKLAPIHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYKEQWIQRFPPEEHPVLALPGAPAQFPVLEEHRALQKYMVWSDEMVKTGEAQISTHLIRPYVGIHLRIGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTATPLTMTMCLPDLNEIQRAVKLWVRALNARSIYIATDSESYVPEIQQLFKEKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTAFVKRERDLHGRQSSFFGMDRPSQPRDEF
What is the function of this protein?
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines.  Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer.  Plays a crucial role in NOTCH signaling.  Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend the fucosylation on the NOTCH EGF repeats.  This extended fucosylation is required for optimal ligand binding and canonical NOTCH signaling induced by DELTA1 or JAGGED1 (By similarity).  Fucosylates AGRN and determines its ability to cluster acetylcholine receptors (AChRs) (By similarity).
What are the official names of this protein?
GDP-fucose protein O-fucosyltransferase 1, Peptide-O-fucosyltransferase 1, O-FucT-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 65 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: Y3194_VIBVY
Sequence: MSNTEFHPHIGVGLRLPHHDHFHHHRPALSWLEIHSENYFQPNSFHRQQLNQMAEHYQISCHGIGLSLGSVTGVNPQHLLRLKQLVDDLQPFLVSDHLSWSENGGHYFNDLLPLPYTEEALEVFCRNVLHVQDALKRPILIENPSSYLKYQHSTISEWQFLTEVQRRTDCRLLLDLNNVYVSAFNHGFDCQTYLEAIPAACVDEIHLAGFTIKSLEQGEIWIDTHSQPVSAEVWQLYQQWIAQHGSRHTLIEWDLDLPPVDVLLNEAKKAETLLRASLLHNNPMHPSLALG
What are the official names of this protein?
UPF0276 protein VV3194.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.