PharMolix/UniProtQA huggingface dataset:
Protein: RDGC_YERPE
Sequence: MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICARKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: JADE3_HUMAN
Sequence: MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAESDGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR
What is the function of this protein?
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity.
What are the official names of this protein?
Protein Jade-3, Jade family PHD finger protein 3, PHD finger protein 16.
What is the protein family that this protein belongs to?
Belongs to the JADE family.
Protein: RL7_BACLD
Sequence: MALNIEEIIASVKEATVLELNDLVKAIEEEFGVTAAAPVAVAGGAAAGGAAEEKTEFDLVLAGAGDQKIKVIKVVREITGLGLKEAKELVDNTPKPLKEGIAKEEAEELKAKLEEVGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ATG17_YEAST
Sequence: MNEADVTKFVNNARKTLTDAQLLCSSANLRIVDIKKKLSSWQLSISKLNFLIVGLRQQGKFLYTILKEGIGTKLIQKQWNQAVLVVLVDEMKYWQYEITSKVQRLDGIVNELSISEKDDTDPSKLGDYISRDNVNLLNDKLKEVPVIERQIENIKLQYENMVRKVNKELIDTKLTDVTQKFQSKFGIDNLMETNVAEQFSRELTDLEKDLAEIMNSLTQHFDKTLLLQDKKIDNDEREELFKVVQGDDKELYNIFKTLHEVIDDVDKTILNLGQFLQAKIKEKTELHSEVSEIINDFNRNLEYLLIFKDISNLIDSFKNSCTQDIQTTKELCEFYDNFEESYGNLVLEAKRRKDVANRMKTILKDCEKQLQNLDAQDQEERQNFIAENGTYLPETIWPGKIDDFSSLYTLNYNVKNP
What is the function of this protein?
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation.  Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity.  Plays particularly a role in pexophagy and nucleophagy.  With ATG13, is required for ATG1 activation by autophosphorylation of 'Thr-226'.  Recruits ATG9 to the pre-autophagosomal structure.  Also plays a role in regulation of filamentous growth.
What are the official names of this protein?
Autophagy-related protein 17.
What is the protein family that this protein belongs to?
Belongs to the ATG17 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: 3HAO1_ASPFC
Sequence: MLPPALNIPKWLEENSHLLQPPVNNYCVYHPSSPATAGYTVMIVGGPNARTDYHINTTPEFFYQYRGSMLLKTVDTSVSPPVFQDIPIHEGSIFLLPANTPHCPVRFKDTVGVVMEQPRPKDAVDTMLWFCKKCGEVVWEKRFVCTDLGTQVKEVVEEFAADQEKRTCKACGTIAETRYQEGEVVQPPRFLE
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase 1, 3-hydroxyanthranilate oxygenase 1, 3-HAO-1, 3-hydroxyanthranilic acid dioxygenase 1, HAD-1, Biosynthesis of nicotinic acid protein 1-1.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_SALPK
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPCGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CABC2_PROVU
Sequence: LPTLSHEAFGDIYLFEGELPNTLTTSNNNQLSLSKQHAKDGEQSLKWQYQPQATLTLNNIVNYQDDKNTATPLTFMMWIYNEKPQSSPLTLAFKQNNKIALSFNAELNFTGWRGIAVPFRDMQGSATGQLDQLVITAPNQAGTLFFDQIIMSVPLDNRWAVPDYQTPYVNNAVNTMVSKNWSALLMYDQMFQAHYPTLNFDTEFRDDQTEMASIYQRFEYYQGIRSDKKITPDMLDKHLALWEKLVLTQHADGSITGKALDHPNRQHFMKVEGVFSEGTQKALLDANMLRDVGKTLLQTAIYLRSDSLSATDRKKLEERYLLGTRYVLEQGFTRGSGYQIITHVGYQTRELFDAWFIGRHVLAKNNLLAPTQQAMMWYNATGRIFEKNNEIVDANVDILNTQLQWMIKSLLMLPDYQQRQQALAQLQSWLNKTILSSKGVAGGFKSDGSIFHHSQHYPAYAKDAFGGLAPSVYALSDSPFRLSTSAHERLKDVLLKMRIYTKETQIPVVLSGRHPTGLHKIGIAPFKWMALAGTPDGKQKLDTTLSAAYAKLDNKTHFEGINAESEPVGAWAMNYASMAIQRRASTQSPQQSWLAIARGFSRYLVGNESYENNNRYGRYLQYGQLEIIPADLTQSGFSHAGWDWNRYPGTTTIHLPYNELEAKLNQLPAAGIEEMLLSTESYSGANTLNNNSMFAMKLHGHSKYQQQSLRANKSYFLFDNRVIALGSGIENDDKQHTTETTLFQFAVPKLQSVIINGKKVNQLDTQLTLNNADTLIDPTGNLYKLTKGQTVKFSYQKQHSLDDRNSKPTEQLFATAVISHGKAPSNENYEYAIAIEAQNNKAPEYTVLQHNDQLHAVKDKITQEEGYAFFEATKLKSADATLLSSDAPVMVMAKIQNQQLTLSIVNPDLNLYQGREKDQFDDKGNQIEVSVYSRHWLTAESQSTNSTITVKGIWKLTTPQPGVIIKHHNNNTLITTTTIQATPTVINLVK
What is the function of this protein?
Broad-specificity glycosaminoglycan lyase, which acts in an exolytic fashion, and preferentially degrades the tetra- and hexasaccharide derivatives of chondroitin sulfate and dermatan sulfate produced by the chondroitin sulfate ABC endolyase, to yield the respective disaccharides.  To a lesser extent, is also able to split off disaccharide residues directly from polymeric chondroitin 4- and 6-sulfate, dermatan sulfate, chondroitin, and hyaluronan.  Is not active against keratan sulfate, heparan sulfate, and heparin.
What are the official names of this protein?
Chondroitin sulfate ABC exolyase, Chondroitin ABC exoeliminase, Chondroitin ABC lyase II, Chondroitin sulfate ABC lyase II, ChS ABC lyase II, Chondroitinase ABC II, cABC II, Exochondroitinase ABC.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 8 family.
Protein: DUT_MYCSJ
Sequence: MSTSLAVLRLDRELPMPARAHDGDAGVDLFSARDVELAPGQRELVPTGIAVAIPHGMVGLVHPRSGLAARVGLSIVNSPGTIDAGYRGEIKVSLINLDPHAPIVIRRGDRIAQLLVQRVELPELVEVTSFDEAGLAETTRGEGGHGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: VATL2_KLULA
Sequence: MSQAISEDQYAPLFAPFFGFAGCAFAMILSCLGAAIGTAKSGIGISGIGTFKPELIMKSLIPVVMSGILAVYGLVVAVLIAGGLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGIVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSGN
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit c', V-ATPase subunit c', Proteolipid protein VMA11, V-type proton ATPase 16 kDa proteolipid subunit 2, V-ATPase 16 kDa proteolipid subunit 2, Vacuolar proton pump 16 kDa proteolipid subunit 2, Vacuolar proton pump c' subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SCX3A_ANDCR
Sequence: VESIKDGYIVDDRNCTYFCGRNAYCNEECTKLKGESGYCQWASPYGNACYCYKLPDHVRTKAPGKCNGR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Alpha-toxin Ac3, Neurotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLA1_SPIAU
Sequence: MIINHNMSAINAQRVQGBVTGVTKNMV
What is the function of this protein?
Component of the core of the flagella.
What are the official names of this protein?
Flagellar filament 34 kDa core protein, 34 kDa major core flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: YHCA_BACSU
Sequence: MATGKEKNAKNPMSLLIVLMAGLFLAILNQTLLNVAMPHLMTEFGVSATTIQWLTTGYMLVNGVLIPLSAFLITRFGQRSLFLVAMFCFTLGTLVCGIAPNFSTMLIGRLIQAVGGGILQPLVMTTILLIFPPESRGKGMGIFGLAMMFAPAVGPTLSGWIIEHYTWRIMFYGLVPIGAIVIIVAFFIFKNMVEPQKIKLDTLGAILSIVGFASLLYGVSEAGSDGWTDPIVLSTVIIGAIAIVAFVVQQLRHDDPMLDFRVFKYDIFSLSSVINIIITVALYTGMFLLPIYLQNLVGFTALQSGLLLLPGAIVMLIMSPISGILFDKFGPRPLAIIGLLVTVVTTYQYTQLTIDTPYTHIMLIYSIRAFGMSLLMMPVMTAGMNQLPARLNSHGTAMSNTLRQISGSIGTSLITTIYTNRTTFHYSQIADKTSTADPNFLHAFQNAVSNLMVNMNVSYDTAKTYVYSHIYKHASLDSNVMGINDAFMWATLFCVAGLILSIFLRDVRKDKLRKKKKEELSLLPAPKEAKES
What are the official names of this protein?
Uncharacterized MFS-type transporter YhcA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_PROM4
Sequence: MSFSGHSARKRFGQHWLKDVAILEKIVEAAELCENDRVLEIGPGRGALTHKLLNSKVSLVHAIELDTDLVVGLRERFFHETRFSLKGGDALKISLLPPDGIEVNKVVANIPYNITSPLLERLIGKLGFFPETRYERLVLLLQKEVADRILAMPGQSSFSAMSVRVQLLCKSRSVCDVSPKCFKPSPKVHSKVVVIEPFAFSERLNVDIEKRVESLLRTAFLGRRKKLRNTLASIRPLNQLESLADQLGISLNQRPQEISPMMWVSLAKRIHDMDKLVGEIQS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_HALWD
Sequence: MQQARVRLAGTSPDDLDDICDDVRDIADTTGVNLSGPIPLPTKTLEIPTRKSPDGEGTATWEHWEMRVHKRLIDIDADERALRQLMRIQVPNDVSIEIVLED
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: BSD_ASPTE
Sequence: MPLSQEESTLIERATATINSIPISEDYSVASAALSSDGRIFTGVNVYHFTGGPCAELVVLGTAAAAAAGNLTCIVAIGNENRGILSPCGRCRQVLLDLHPGIKAIVKDSDGQPTAVGIRELLPSGYVWEG
What is the function of this protein?
Catalyzes the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.
What are the official names of this protein?
Blasticidin-S deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: IF2_LACAC
Sequence: MAKKRIYEVAKEVGVDNKVVVQKAKDLGFDVKNHMSSIDDSQVAKLKSSFQNSAPAEKKAEKSATKNNKIKISVSSIRKNEKKPEENNTPKKSNRRRNNKRRSSDRARDNKERDAKSNTGRPKAAALLQQFKQKQRAEEGQLNREAQKAKKEYHEHLKHPKKEQSEKDNKKTVKESNNKKVEQQVEKKVIGPKILKPSPARLKKNQPADNKEKVTTPRVTIPEAPKEEKRGNGRGRNMGKPGRKGKNQFVNGHSERSDRSERKRRKNKKHQQEQQKPRKQITKRKERPLPDILVYEEGMNAQDIGKLIHREPAEIVKKLFMLGVMTNQNQSLDKDTIELLAAEYGIDAKQKVHEDISDIDTLYDKRMEASKKSKNQIKRPPVVTIMGHVDHGKTTLLDRLRHTHVSAHEAGGITQRIGAYQVRLDDRLITFLDTPGHAAFSNMRARGAEITDIVVLVVAADDGVMPQTVEAIDHAKSANVPIIVAINKMDKPGANPQHVTEELMKYNLIPEDYGGDTIFVNISAKTGQNVDDLLQMILLQADVMELKANPDEMAIGTVIEARLSRGRGPVADVLIQQGTLNIGDPIVVGDTFGRVRTMTNDRGRQVKKATPSEPVEITGLNDVPESADKLVEFKDEKTARSVGEARAQQSLQKSRENVQHVTLDNLFDTMKKENMKEVDIVLKADVQGSVEALQQSLEKIEVEGVRVNIIHSGVGAINESDVTLAGASNAFIIGFNVRPTATAKSQAETDGVDIRLYSIIYKAIDDVTAAMKGMLEPTYEEKVIGNLTVRETWKVSKVGTIAGSFVDKGIVKNDSKIRVIRDGIVKYDGEIASLKRFKDDVKEVKQGNDCGLTIKDYNDIKVGDEFEVYEMQQVEPK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_PROM0
Sequence: MDNRTAIIKQPDNISSFHDVYKLQKEYQEALILDNSNPDFIWIGEHQLCYTLGRGSNYDNLLFSLNDAKYDVFKIDRGGEVTCHMPGQLVTYLVLDLKNFNKDLNWYLRKIEEIIIKILGAFNIDCHSRKGFTGVWIGNKKIASIGIGCKKWITINGFSINIDCELENFNKIVPCGIENCLMANMIDYNKNLNIQEVKRIVKKTIEEEFNFDFISK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTPR_LACGA
Sequence: MSDLRITLDPDFIAQTKKEVTPHWGELGWVTYKRTYARWLDDKNRSENWDETVKRVIEGNINLDPRLKNNPSKKTIHELTAEAKQLFRLVYGLAATPSGRNLWISGTDYQKRNGDSLNNCWFISIRPQKYGNSHIVPAYLTQDQVAPSMPFSFLFDQLMKGGGVGFSVVDENINQIPKLDQKVDLTIVIDKQSKSYDASLKLGATDLDEWKKTNQEKEDYIYYKLPDTREGWVLANARLIDMHFNSTNPENKKKLVLDISDIRPYGAKIHGFGGTASGPMPLIEMLFDINQILNERAGQKLTAVDATDICNLIGKTVVAGNVRRSAELALGSSNNQDFITMKQDKKKLYHHRWASNNSVAINSEFDNYQPIADSILHNGEPGVVNLELSRNYGRIKDGYQAGIDGEVEGTNPCGEISLANGEPCNLFEVFPFIAQKQGWDLKEAFKLAARYTKRVTFSPYDWEVSRKIINKNRRIGVSMSGIQDWILSTFGHRVVTGFKTATDSETGKEIKDPVYDPEIIKTVDGLYQAVVDADKDYSQELNCNTSIKHTTVKPSGTVAKLAGVSEGMHFHYSGYLIQRIRFQETDPLLPALKDCGYRTEPDIYTPHTICVEFPIKAANADSDNFASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQNDESDQIAPLLHQYRYAIKSTSLLPYYGGSLKQAPKEPISKEKYEKADNHITGNVEIVFEQTNEDQKGLELVDQSDCDNGACPIK
What are the official names of this protein?
Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, RTPR.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: NCAP_GOGV
Sequence: MAAFQKAAVNQLALKKKLNKMLAPYQRELNNQIFKDVKALRVGLDINKVNDTLRRLRKETKGPNDLKNLRDLNETAAGLSGMVATQRTVEIDSSLMSDEELIQCIENIDVIKKKAEYKGGSRPRISEFESETGMSKSDHEMFNKLFNRFAPKKDPGPAAFSTPKSWVGISPADLANQFGTSPAITICLIMMRTNSPFKQILDALHDISLLDQGMFVNASVVKAMTSQHPCLDCVEYTVPKNSSGYNITVKAVVKAANVLSKLPKVEKLVIDDDNRVEIIRTLLTIQRELNIKIQVNEERGLFEDIFYKICVSPNGPCVVSIRSELTGRGWENTIFRLRRPPPYAPRLYPDLMDLDLDALPPVKGDKKTEEESKIYIFKPAADEIDEYIRSPESASSDSEIPDPRVLYMANACEDLFKGGDSVFMDIEGTAQDPVEIALFNPDTGKFVHIFRMPKDKDGFKKASKHAHGLLLDDISDHPDLQTDKNIEAFFSKVPLSARIFCQGSDIEECLKFFGRKDLKPTDCKWKREEFMKYHENILDELSEVFPCKHSGTVKDKKGALTAPHCALLDCLMFSRTASGGKKTKDPTPATI
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: UNG_BACSU
Sequence: MKQLLQDSWWNQLKEEFEKPYYQELREMLKREYAEQTIYPDSRDIFNALHYTSYDDVKVVILGQDPYHGPGQAQGLSFSVKPGVKQPPSLKNIFLELQQDIGCSIPNHGSLVSWAKQGVLLLNTVLTVRRGQANSHKGKGWERLTDRIIDVLSERERPVIFILWGRHAQMKKERIDTSKHFIIESTHPSPFSARNGFFGSRPFSRANAYLEKMGEAPIDWCIKDL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_BURP1
Sequence: MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGFAEMLRSREVLRVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWIFDEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLGVEPFSAAFSGALLFGRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYFCPNCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: VIRBA_BRUA2
Sequence: MTQENIPVQPGTLDGERGLPTVNENGSGRTRKVLLFLFVVGFIVVLLLLLVFHMRGNAENNHHSDKTMVQTSTVPMRTFKLPPPPPPAPPEPPAPPPAPAMPIAEPAAAALSLPPLPDDTPAKDDVLDKSASALMVVTKSSGDTNAQTAGDTVVQTTNARIQALLDSQKNTKQDAGSLGTLLHGTQTDARMASLLRNRDFLLAKGSIINCALQTRLDSTVPGMAACVVTRNMYSDNGKVLLIERGSTISGEYDANVKQGMARIYVLWTRVKTPNGVVIDLDSPGADPLGGAGLPGYIDSHFWKRFGGALMLSTIETLGRYATQKVGGGGSNQINLNTGGGESTSNLASTALKDTINIPPTLYKNQGEEIGIYIARDLDFSSVYDVKPK
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.  Virb10 seems to be per se essential for intracellular multiplication within non-professional phagocytes and is essential for pathogenesis in mice.
What are the official names of this protein?
Type IV secretion system protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TMCAL_BACAC
Sequence: MQQTKKLTHSDITIAVMSGPFLQRGEPALVSKWYRTKMALACGVDLVVELPYAFSTQKAETFANGAISILNALHVSEICFGSEDGQIENFYNTISVQKNEEETFNRLVKQFMNAGNSYAKATSEAFLHILSSEKNIDMSQPNNILGFQYIKAILMQNSSMQAQTIKRFASHYHDETFNDQHIASATSIRKQLFSENSSFTEIESFIPKATASLLASYKQNYGTLHNWEQYFSFFKYKLMTMSPENLRHIYEIEEGLEHRILSKIQTSSSFHSFMESLKTKRYTWTRLQRACTHILTNTTKEEIYCANIEQHAPYIRLLGMSQKGQTYLSKNKKKIELPILTHTKTFDHPTLHIERKANSVYFSIMKEPLRTQLLKRDATHHPIRYDETTAKFL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_BUCBP
Sequence: MKRNYKIAVLPGDGIGPEIMREGYKILRILKSKLSLNIMTQEFDVGGVAIDKYGVALPKKTLQGCRDSHAILFGSIGGPKWEDLPSHLQPERGALLPLRKYFNLFSNLRLARIYSGLEKLSPLKSRISNLGCDILCVRELTGGIYFGDPKGSKVSKSLNCAFDTEVYYQFEIERIAHMAFDLALTRRCKVTSIDKANVLESSMFWRKIVNRISTQYSQVKLSHLYVDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASLNDKNFGLYEPAGGSAPDIKGKNIANPIALILSIGMMMRYSFKLYDVADLIDWAVNKTLKLGYRTQDISENNKFINTSSMGDIIAEILANRIHKI
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSB_XANCP
Sequence: MQIGPYTIAPKVILAPMAGVTDKPFRLLCKRLGAGLAVSEMTISDPRFWGTRKSLHRMDHAGEPDPISVQIAGTEPQQLAEAARYNVDHGAQLIDINMGCPAKKVCNAWAGSALMRDEDLVARILSAVVRAVDVPVTLKIRTGWDCDHRNGPTIARIAQDCGIAALAVHGRTRDQHYTGTAEYATIAQIKAALQIPVIANGDIDSPQKAAQVLRDTGVDAVMIGRAAQGRPWIFGEVAHYLATGALLPPPSLAFVRDTLLGHLEALHAFYGQPQGVRIARKHLGWYAKDHPQSADFRAVVNRAETPEAQLALTRDYFDALIAGVPPPLHAAA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.