PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_SHIBS
Sequence: MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RBFA_MARN8
Sequence: MAREYSRVDRIGDQMQRELAQLIQREVKDPRVGMVTVNDVKVSRDLGYADIYISLLSTEELTEDSPEVQDSLTVLNKASGFLRGQVGRAMKLRVVPHLRFHFDKLLGQSRKMDRLIREAVGDKPAVPRDDNDDPVSDNPERDA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS3_XANST
Sequence: MAAVGANATLLTNTKSTVEPVRPLANFPPSVWGDMFLSFSLDNSKMEEYAKAMEKPKQEVRRLILDPTMDSNKKLSLIYVVHRLGLTYMFLKEIEGQLDRLFEEFNLEDYVDVDLHTISINFQAFRHLGYKLPCDVFNKFKNNDSNAFKESIASDVRGLLGLYESAQLRVKGEKILDDASAFAETKLKSLVNTLEGSLAQQVKQALKRPFHQGMPMVEARLYFTNYQEEFSKYDSLLKLAKLHFNYLQLQQKEELRIVSKWWKDMRFQETTPYIRDRVPEIYLWILGLYFEPKYSLARIIATKITLFLVVLDDTYDAYGTLEELRLLTHAINRWDMRAMSDIPEYIRPFYKILLDEYAELEKQLAKEGRLKSVIASKEAFQDIARGYIEEAEWTNSGYVASFPEYMKNGLITSAYNVISKSALVGMGEVVSADALAWYESHPKILQASELISRLQDDVMTYQFERERGQSATGVDSYIKTYGVSEKEAIEELKKMIENAWKDINEGCLKPREVSMDLLAPILNLARMIDVVYRYDDGFTFPGKTLKEYITLLFVDSLPM
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:26858282).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (+)-(R)-germacrene A (PubMed:26858282).
What are the official names of this protein?
Sesquiterpene synthase TPS3, Germacrene A synthase, Terpene synthase 3, XsTPS3.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BACC0
Sequence: MKRTYQPNKRKRSKVHGFRSRMSTANGRKVLAARRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NHAB_VIBC3
Sequence: MPMSLGNAFIKNFLGKAPDWYKVAIIAFLIINPIVFFFINPFLAGWLLVVEFIFTLAMALKCYPLQPGGLLAIEAIAIGMTSPGQVKHELVANIEVLLLLVFMVAGIYFMKQLLLFIFTKILLGIRSKVLLSIAFSVTAAFLSAFLDALTVIAVIISVAVGFYSIYHKVASGQSVHSSHDHTHDEGISELTRDDLENYRAFLRSLLMHAGVGTALGGVTTMVGEPQNLIIADQAGWQFGEFLLRMAPVTVPVFIAGMLTCMLVEKFRIFGYGARLPANVRQILLDFDSEERKNRTNQDVAKLWVQGAIAVWLIVGLALHLAAVGLIGLSVIILATAFTGVIEEHSLGKAFEEALPFTALLAVFFSIVAVIIDQELFKPVIDAVLNVEDHGTQLALFYVANGLLSMVSDNVFVGTVYITEVKTALMEGMISRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVIMAFPYTLALSLVGFIGIMFLLEPMTEVFYSLGWISHHVAPAADALLQSGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLID_CAMJE
Sequence: MAFGSLSSLGFGSGVLTQDTIDKLKEAEQKARIDPYTKKIEENTTKQKDLTEIKTKLLSFQTAVSSLADATVFAKRKVVGSISDNPPASLTVNSGVALQSMNINVTQLAQKDVYQSKGLANDGGFVNAQLNGTADLTFFSNGKEYTVTVDKNTTYRDLADKINEASGGEIVAKIVNTGEKGTPYRLTLTSKETGEDSAISFYAGKKDSNGKYQKDINAEKIFDDLGWGLDVSASIDPDKDKKGYGIKDASLHIQTAQNAEFTLDGIKMFRSSNTVTDLGVGMTLTLNKTGEINFDVQQDFEGVTKAMQDLVDAYNDLVTNLNAATDYNSETGTKGTLQGISEVNSIRSSILADLFDSQVVDGTTEDANGNKVNTKVMLSMQDFGLSLNDAGTLSFDSSKFEQKVKEDPDSTESFFSNITKYEDINHTGEVIKTGSLSKYLNSNGGNTNGLEFKPGDFTIVFNNQTYDLSKNSDGTNFKLTGKTEEELLQNLANHINSKGIEGLKVKVESYNQNNVTGFRLNFSGDGSSDFSIKGDANILKELGLSDVNITSKPIEGKGIFSKLKATLQEMTGKDGSITKYDESLTNDIKSLNTSKDSTQAMIDTRYDTMANQWLQYESILNKLNQQLNTVTNMINAANNSNN
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: DADA_STUS1
Sequence: MRVLVLGSGVVGTASAYYLARAGFEVVVVDRQPAVAMETSFANAGQVSPGYASPWAAPGVPLKAMKWLLQRHAPLAIKLTGDIDQYLWMAQMLRNCTAARYAVNKERMVRLSEYSRDCLDELRAETGIAYEGRQLGTTQLFRTQAQLDAAAKDIAVLERSGVPYELLDRASIARVEPALAKVSHKLSGALRLPNDQTGDCQLFTTRLAEMARALGVEFRFEQNIQRLEHAGDRIAGVWIDGKLETADRYVLALGSYSPQMLKPLGIRAPVYPLKGYSLTVPISDPAMAPQSTVLDETYKVAITRFDQRIRVGGMAEIAGHDLSLDPRRRETLEMVVGDLYPQGGDPSDAVFWTGLRPATPDGTPIIGATPYRNLFLNTGHGTLGWTMACGSGRVLADLLASKRPQISTEGLDIFRYGKHKENHKHAHPAAAH
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: IL17F_MOUSE
Sequence: MKCTRETAMVKSLLLLMLGLAILREVAARKNPKAGVPALQKAGNCPPLEDNTVRVDIRIFNQNQGISVPREFQNRSSSPWDYNITRDPHRFPSEIAEAQCRHSGCINAQGQEDSTMNSVAIQQEILVLRREPQGCSNSFRLEKMLLKVGCTCVKPIVHQAA
What is the function of this protein?
Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:23255360, PubMed:18025225, PubMed:19144317).  IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains.  This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation (PubMed:17911633, PubMed:15477493, PubMed:18025225).  IL17A-IL17F is primarily involved in host defense against extracellular bacteria and fungi by inducing neutrophilic inflammation (PubMed:18025225, PubMed:23255360).  As signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites (PubMed:18025225).  Stimulates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers (PubMed:19144317).  IL17F homodimer can signal via IL17RC homodimeric receptor complex, triggering downstream activation of TRAF6 and NF-kappa-B signaling pathway (PubMed:28813677).  Via IL17RC induces transcriptional activation of IL33, a potent cytokine that stimulates group 2 innate lymphoid cells and adaptive T-helper 2 cells involved in pulmonary allergic response to fungi (PubMed:28813677).  Likely via IL17RC, promotes sympathetic innervation of peripheral organs by coordinating the communication between gamma-delta T cells and parenchymal cells.  Stimulates sympathetic innervation of thermogenic adipose tissue by driving TGFB1 expression (PubMed:32076265).  Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes (PubMed:29915298).
What are the official names of this protein?
Interleukin-17F, IL-17F.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_SALDC
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PA2A2_BOTIN
Sequence: NLWQFGRENQEVMGQHLPFHYLSYGCYCGWGGIEPKCCYVHDCCYGKLDLYTYSKETGDLVCGGDDPCQKQLCECDRVAALCFQDNKDTYDQKPYNAENCQEASEAC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 2, svPLA2, BinTX-II, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_RICCK
Sequence: MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSLSFVTGPILIKFLRTLQKNGQPIRLDGPESHQTKAGTPTMGGIMIILSSCLATLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVTKNNHYGVRGKSKLLLQGIISLIICILLEYTDKNPSHLLNIPFFKNLSLDLGYFYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSNYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGSILGIISVITKHEVVLSIVGGLFVVETTSVILQVYYFKATKGKRIFKMAPLHHHFEKHGWEESKVVIRFWIISVIFALIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPA_PSEPK
Sequence: MTTVQEAVPNLIPTQDATPRPAPKKVEAGVKLRGADKVARIPVKIIPTDELPKKPDWIRVRIPVSPEVDRIKQLLRKHKLHSVCEEASCPNLGECFSGGTATFMIMGDICTRRCPFCDVGHGRPKPLDLDEPKNLAVAIADLRLKYVVITSVDRDDLRDGGAQHFADCIREIRALSPGVQLETLVPDYRGRMDVALEITAQEPPDVFNHNLETVPRLYKAARPGSDYDWSLDLLQKFKQLVPHVPTKSGLMLGLGETDEEVIEVMHRMREHDIDMLTLGQYLQPSRSHLPVQRFVHPDTFAWFAEEGYKMGFKNVASGPLVRSSYHADQQAHEAKIKL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEDD_PEDAC
Sequence: MWTQKWHKYYTAQVDENDCGLAALNMILKYYGSDYMLAHLRQLAKTTADGTTVLGLVKAAKHLNLNAEAVRADMDALTASQLPLPVIVHVFKKNKLPHYYVVYQVTENDLIIGDPDPTVKTTKISKSQFAKEWTQIAIIIAPTVKYKPIKESRHTLIDLVPLLIKQKRLIGLIITAAAITTLISIAGAYFFQLIIDTYLPHLMTNRLSLVAIGLIVAYAFQAIINYIQSFFTIVLGQRLMIDIVLKYVHHLFDLPMNFFTTRHVGEMTSRFSDASKIIDALGSTTLTLFLDMWILLAVGLFLAYQNINLFLCSLVVVPIYISIVWLFKKTFNRLNQDTMESNAVLNSAIIESLSGIETIKSLTGEATTKKKIDTLFSDLLHKNLAYQKADQGQQAIKAATKLILTIVILWWGTFFVMRHQLSLGQLLTYNALLAYFLTPLENIINLQPKLQAARVANNRLNEVYLVESEFSKSREITALEQLNGDIEVNHVSFNYGYCSNILEDVSLTIPHHQKITIVGMSGSGKTTLAKLLVGFFEPQEQHGEIQINHHNISDISRTILRQYINYVPQEPFIFSGSVLENLLLGSRPGVTQQMIDQACSFAEIKTDIENLPQGYHTRLSESGFNLSGGQKQRLSIARALLSPAQCFIFDESTSNLDTITEHKIVSKLLFMKDKTIIFVAHRLNIASQTDKVVVLDHGKIVEQGSHRQLLNYNGYYARLIHNQE
What is the function of this protein?
Involved in the export process of the bacteriocin pediocin PA-1/AcH.  Is also essential for pediocin production.
What are the official names of this protein?
Pediocin PA-1 transport/processing ATP-binding protein PedD, Pediocin AcH transport ATP-binding protein PapD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Pediocin PA-1 exporter (TC 3.A.1.112.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBD_TRIEI
Sequence: MTVAVGRPQSQRGAFDVLDDWLKRDRFVFVGWSGILLFPCAFLSIGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAISSPAYSMGHSLLFLWGPEAQWDFARWCQIGGLWSFTALHGAFALIGFCLRQIEIARLVGIRPYNAIAFTGPIAVFVSVFLMYPLGQSSWFFAPSFGVAGIFRFILFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFQDGEAANTFRAFEPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSSIGIVGLAFNLRAYDFVSQELRAADDPEFETFYTKNILLNEGIRAWMSPADQPHQNFMFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL36_SYNPW
Sequence: MKVRASVKKMCDKCRVIRRHGRVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: IF12_DECAR
Sequence: MAKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPYDLSKGRITFRHIENRGTPNPQAQRRRY
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOPO_BOVIN
Sequence: MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMELGLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARDGRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSFNREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGPTVLNISGGKG
What is the function of this protein?
Conversion of dopamine to noradrenaline.
What are the official names of this protein?
Dopamine beta-hydroxylase, Dopamine beta-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein.
Protein: 7OMT8_MEDSA
Sequence: MASSINGRKPSEIFKAQALLYKHIYAFIDSMSLKWAVEMNIPNIIQNHGKPISLSNLVSILQVPSSKIGNVRRLMRYLAHNGFFEIITKEEESYALTVASELLVRGSDLCLAPMVECVLDPTLSGSYHELKKWIYEEDLTLFGVTLGSGFWDFLDKNPEYNTSFNDAMASDSKLINLALRDCDFVFDGLESIVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPNADAVLLKYILHNWTDKDCLRILKKCKEAVTNDGKRGKVTIIDMVIDKKKDENQVTQIKLLMDVNMACLNGKERNEEEWKKLFIEAGFQHYKISPLTGFLSLIEIYP
What is the function of this protein?
Transfers a methyl group to 7-hydroxyls of the isoflavones daidzein, genistein and 6,7,4'-trihydroxyisoflavone.  Can also methylate (+)6a-hydroxymaackiain with lower efficiency.
What are the official names of this protein?
Isoflavone-7-O-methyltransferase 8, 7-IOMT-8, Isoflavone-O-methyltransferase 8.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: CTL1_SCHPO
Sequence: MFSDYASRFLAQSRFSSVDQRNFKYPTSRSNLQSVSIDRNSSIDSHETDLSAGSSSLHGLNSLIDSGSIHWQLREQEQSNSHISRNENELFSKENSIYNGNFSENLGVQPNPQTISHESVNEEYTELPYDAHLPSEQKVPDRKWGLTFGFLTLALFTYSFLMVWRTNPNIPPATSPYAAIQKAFPLFHKDAIICMMLSVIWLFCLVAIPRFLYFLLASVPLTMFAFAVYLLKASRIHLETSIQPKLMLLTGIILLVAPILLSYYVWRRRIHFETSFNIIRLACRVIADIPQITLIFISFLFSFYVLIFIWVRLFARLFLRGSTLVGSVWVLPRSSWVLASFYSLHFLWLCTFFHALQCAIISSIVSQWFFYRDTKSSATKTNLVSHFFYHVVSNQYGLCAFSSFLVVITKVPLHFLPTWLRHVSRIVYYMFSKTSASYVTSPLTLAYASIYSVPYMNASKALYQIEQLNRVGLRRRSYYFSKYTLLAARSLLAIGVGVTSWNYSIHENGVFYGYIVGLLGGFLAWLIIGAIEGGLSMIVDALLICSIIDISSCQGDPNGSHCFEAWQLFESNGY
What is the function of this protein?
Required for the normal organization of the preautophagosomal structure (PAS) and for the correct subcellular location of atg9.
What are the official names of this protein?
Choline transporter-like protein ctl1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Preautophagosomal structure membrane; Multi-pass membrane protein.
Protein: FLID_XENNE
Sequence: MASISSLGAGSGMDLGSLLDKLQAAEKKRLEPLAQQQTSYKAKLTGFGTLKGSLEKLKSASEELKKFDKLNTTKTNGDHKTFTPSTDSKASPGNYEIEVQQLAKAQSLQSTEVSGVKKLLGEQGKGTRTIIITQPGEKEPMKISLKDDETSLVEIRDAINKKEGNVNASIIKADENGTEEEGKSYLILTSKKAGTRSIMTIKVEGDDELGKLLNYTSDGKGGGSGAMTQKVGAANAKLTVNGIPIERQTNEIKDAPEGIILNLKKVSETEEVIVKVNGEDKKIPRPKTEILVVSRDIEPMKEAIKKWVDSYNELQTTFDSLAKFKPVGKGEAASKDNGALLGDGTLKGIQSQLRHQLFAAQDVADIATLNKLGIKQKLDGTLEISDEKLEKNLKEKSADVKAFFMGDGAKPGSTQTYNLLKETLDGHEGTIATATEGINKRLKTLERQVEQTNRNIDATMERYKRQFTELDKLVNSLNNTSSSLFQLLR
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: CBPE_LOPAM
Sequence: MKQICSIVLLGAAVVSLVSAAGSDSEISFEYHRYEELRKALVSVWLQCPTIARIYTIGESFEGRELLVLEMSDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHSTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGVDLNRNFPDLDRIIYTNEREGGANNHLLQNMKKAVDENTKLAPETKAVIHWIMEIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVIFKSLAKAFSIYNPVMSDPQRPPCRKHDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPNEDTLKTYWEQNRNSLVNYIEQVHRGVKGYVRDLQGNPIFNATISVEGIDHDITTAKDGDYWRLLRQGNYKVAASAPGYLTVIKKVAVPHSPATRVDFELESLMERKEEEREELMDWWKMMSETLNF
What is the function of this protein?
Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing.
What are the official names of this protein?
Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
Protein: NIBA2_HUMAN
Sequence: MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIGNSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSAGVQTEF
What is the function of this protein?
May play a role in apoptosis suppression.  May promote melanoma cell invasion in vitro.
What are the official names of this protein?
Protein Niban 2, Meg-3, Melanoma invasion by ERK, MINERVA, Niban-like protein 1, Protein FAM129B.
What is the protein family that this protein belongs to?
Belongs to the Niban family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell junction, adherens junction. Membrane; Lipid-anchor. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
Protein: HBAD_ERYML
Sequence: VLTAEDRRLLQASVGKLGCRLEDIGADALNRLLITFPQSKTYFSHFNLSPGSKDIIHQGEKVGKALDSALKHLDDIRGTLSQLSDLHAYNLRVDPVNFQLLSKCIHVSLATHLRNEYSASVTLAWDKFLELVADVLSEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ISCS_SHESH
Sequence: MKLPIYLDYAATTPVDPRVAEKMMQCMTMDGIFGNPASRSHRYGWQAEEAVDIARNQVAELINADPREIVFTSGATESDNLAIKGVAHFYHKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPESNGLIPLETIEAAMREDTILVSIMHVNNEIGVIHDISAIGELCRSKKIIFHVDAAQSAGKLPIDVQSMKVDLISISAHKMYGPKGIGALYVRRKPRIRLEATMHGGGHERGMRSGTLATHQIVGMGEAAAIAKADMTTDNARIRTLRDRLWNGVKGIEETYINGDFEQSYCGSLNVSFNFVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIETINKSIGDLREMSPLWEMFQDGVDLDKVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.