PharMolix/UniProtQA huggingface dataset:
Protein: NDUB2_HUMAN
Sequence: MSALTRLASFARVGGRLFRSGCARTAGDGGVRHAGGGVHIEPRYRQFPQLTRSQVFQSEFFSGLMWFWILWRFWHDSEEVLGHFPYPDPSQWTDEELGIPPDDED
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial, Complex I-AGGG, CI-AGGG, NADH-ubiquinone oxidoreductase AGGG subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: OMA1_MOUSE
Sequence: MSLLYGLQSTRINRFLSGVNNLANRRQWTPPASCPLAPKLRAVNAYWGLNTVSHCHSVTLLPRNFLFCRTLNHKKSRCLSSAQSKELGVLTYRCTVRGDSVLRQGARKVAGVPALAASCSPSCPAVIEARSFRTSARVQAAPVPLLLLILKPVQKLLAIIVGRGIRKWWQALPPNKKELFKDSVRKNKWRLLLGLSAFGLLFVVFYFTHLEVSPVTGRSKLLLVGKEHFRLLSDLEYEVWMEEFKNDLLPERDPRYLTVKEMVYHLTQCNRDVPGISETNWVVHVVDSPAVNAFVLPNGQVFIFTGLLNSVTDVHQLSFLLGHEIAHAVLGHAAEKASLVHLLDFLGMIFLTMIWAICPRDSLAVLGQWIQSKLQEYMFDRPYSRTLEAEADKVGLQLAAKACADVRASSVFWQQMEFSESLHGYPKLPEWLSTHPSHGNRAEYLDRLIPQALKLREVCNCPPLSGPDPRLLFRLTVKRFLEDSEKEDLNITVKKQKTDALPMQKQEQIPLTYVLEKRTAG
What is the function of this protein?
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria (PubMed:20038678, PubMed:22433842, PubMed:24550258, PubMed:24719224, PubMed:24616225, PubMed:26785494).  Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA1, UQCC3 and DELE1 (PubMed:20038678, PubMed:22433842, PubMed:24550258, PubMed:24616225, PubMed:26785494).  Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion (PubMed:20038678, PubMed:22433842, PubMed:24550258, PubMed:24616225, PubMed:26785494, PubMed:26783299).  Also acts as a regulator of apoptosis: upon BAK and BAX aggregation, mediates cleavage of OPA1, leading to the remodeling of mitochondrial cristae and allowing the release of cytochrome c from mitochondrial cristae (By similarity).  In depolarized mitochondria, may also act as a backup protease for PINK1 by mediating PINK1 cleavage and promoting its subsequent degradation by the proteasome (By similarity).  May also cleave UQCC3 in response to mitochondrial depolarization (By similarity).  Also acts as an activator of the integrated stress response (ISR): in response to mitochondrial stress, mediates cleavage of DELE1 to generate the processed form of DELE1 (S-DELE1), which translocates to the cytosol and activates EIF2AK1/HRI to trigger the ISR (By similarity).  Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions (PubMed:22433842).  Binds cardiolipin, possibly regulating its protein turnover (PubMed:31819158).  Required for the stability of the respiratory supercomplexes (PubMed:26365306).
What are the official names of this protein?
Metalloendopeptidase OMA1, mitochondrial, Overlapping with the m-AAA protease 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MGSA_BRUA1
Sequence: MTQRLRIALIAHDQKKDDMVAFARAHEQALSRYDIVATGTTGGLIQDACPSLNIHRVKSGPLGGDQQIGAMIAEGTVEVLIFFIDPLSPLPHDVDVKALTRLGSVYDIPMALNRATAEKLVRALD
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: EFTS_STAAS
Sequence: MATISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVETKGNDAVIVEINSETDFVARNEGFQELVKEIANQVLDTKAETVEALMETTLPNGKSVDERIKEAISTIGEKLSVRRFAIRTKTDNDAFGAYLHMGGRIGVLTVVEGSTDEEAARDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEGKPENIVEKMVEGRLRKYLQEICAVDQDFVKNPDVTVEAFLKTKGGKLVDFVRYEVGEGMEKREENFADEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP5_PIG
Sequence: MKKEVCSLAFLKAVFAEFLATLIFVFFGLASALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAGILYGLAPGNARGNLAVNSLNNNTTPGQAVVVEMILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAAVAAILYFYLLFPNSLSLSERVAVVKGTYESEEDWEEQREERKKTMELTAH
What is the function of this protein?
Forms a water-specific channel (By similarity).  Plays an important role in fluid secretion in salivary glands.  Required for TRPV4 activation by hypotonicity.  Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells.  Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
What are the official names of this protein?
Aquaporin-5, AQP-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Protein: CPFC_STAES
Sequence: MTKTIGLLVMAYGTPYKESDIEPYYTDIRRGKKPTEEELQDLKDRYEFIGGLSPLAGTTDRQAEALLEALNKEQDDVNFKLYIGLKHISPYIEEAVEQMHNDGIKEAVTVVLAPHYSSFSVGSYDQRAQEKADEYGIQLTHIKHYYQQPKFIKYWTEKINETLEQIPNQEHDETVLVVSAHSLPKGLIERNNDPYPHELHETAEILKQESNIIHVAEGWQSEGNTGTPWLGPDVQDLTRDLYKEHQFKHFIYTPVGFVCEHLEVLYDNDYECKVVCDDIGVNYYRPEMPNTHPLFIGAIVDEIQSHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VDAC4_ORYSJ
Sequence: MEAETECKVPGVYSETGIPVEDPAPGLNSDVSKKDAPPAVAAPGPGLYFEIGKKARDLLYKDFHTDQKFTLTTYTNNGVVITAASTMKDEAIFSEIQTKLKSNNVMLDVKATSDSQVLTTITTEDLGVSGLKQIVSLPFPYQTAGKAELQYLHDYAGISLGVGLTSKPLVNLSGVFGNKSVAVGADVAVDTSTGDFTKYDAGLTINNSDLAADLTLNNKGDSLTASYYHLVNKESGTAAGAELTHSFSTKENTLSFGMQHALDPLTTVKARYNNHGMVSALIQHEWRPKSFLTLSAEVDTKAIDKASKVGLSLVLKP
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
What are the official names of this protein?
Mitochondrial outer membrane protein porin 4, Voltage-dependent anion-selective channel protein 4, OsVDAC4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: T184B_BOVIN
Sequence: MTVRGAALAPDPASPTTAAASPSISVIPEGSPTAMEQPVFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEALVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARVSVGEGTVAAGYQDFIICVEMFFAALALRHAFTYKVYADKRVDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEPGPTWRGGAHGLSRSHSLSGARDNEKTLLLSSDDEF
What is the function of this protein?
May activate the MAP kinase signaling pathway.
What are the official names of this protein?
Transmembrane protein 184B.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NADD_SYNY3
Sequence: MKIALFGTSADPPTLAHRAILIWLAQHFDQVAVWAADNPFKQGPNPETGHWASLGDRQAMLKLLVEDVQKDYATVQIWEDLSDRRSLISLQRAQQRWGLEPDYALVVGADLIRQISQWYAVKELLPAVQLVIFPRPGYGINQADLDKLAQLGGHYQLVNQGDDQAITPPISSSIYRQIRDDDLIPDPVQSYIQQRQLYRQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SBP1_ANTMA
Sequence: MDTSKGEGKRVIKLPGSQEQGEEEDDIGEDSKKTRALTPSGKRASGSTQRSCQVENCAAEMTNAKPYHRRHKVCEFHAKAPVVLHSGLQQRFCQQCSRFHELSEFDEAKRSCRRRLAGHNERRRKSSHDTH
What is the function of this protein?
Probable transcriptional factor.  Binds to the promoter of the SQUAMOSA gene.
What are the official names of this protein?
Squamosa promoter-binding protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGL20_ORYSJ
Sequence: MERRPLHLHLLLFFSAWLLLLLLQGVSSLQFRREDFPDGFAFGAGTAAYQYEGAAAEDGRTPSIWDTYTHSGRHPEDGTGDVASDGYHKYKEDVKLMTEIGLEAYRFTISWSRLIPSGRGAVNPKGLQFYNNMINELVKAGIQIQVALYHSDLPQSLQDEYGGWINPKIVDDFTAYADVCFREFGDRVAHWTTVLEPNVMAQGCYDTGILPPNHCSYPFGNNCTGGNSTVEPYLFIHHNLLAHASAVRLYREKYQVAQKGIIGINMYSLWFYPLTDSAEDIGATERAKQFMYGWILHPLVFGDYPETIKKVVGSRLPFFSNHESELVTNAFDFIGLNHYSSVYTSNNNNVVKAPLQDLTADIATLFRATKNDTPTPEFLPGNTVDPQGLENALEYIRENYGNLTIYIQENGSGAPDGTLDDVERINYLQKYIAATLKAIRNGANVKGYSMWSFIDIYEIFGGYNSWHYGLVAVDFGSTERRRQPRRSASWYSDFLKNNAPIRVEDGSFVSAASHAQL
What are the official names of this protein?
Beta-glucosidase 20, Os5bglu20.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: SYT_THENN
Sequence: MKIKVVLPDGSEREYEKGTKPMEIAREVGIKKVIGAVVDEELWDLKRPLERDCRIRFVTLEDPEAPEFYRHTMAHILAQAVMRLYGKENVKLGIGPTIENGFYYDFDIRNGKLTEEDLPRIEQEMKKIIKENLPIEREEISKDEAKEIFKDQPYKLELIEEIEGDTVTIYRQGEFVDLCRGPHLPSTGVVKHFKLLSVSGAYWRGSEKNPMLTRVYGTAFAKKEDLENYLKFLEEAQKRDHRKLGPQLELFMLNTDYAPGMPFFLPRGVIVLNELMNFSRELHRERGYQEIFTPLIMNEQLWRISGHWDHYAENMYFIEKGEERYAVKPMNCPGHILVYKSRAVSYRDLPLRFFEFGRVHRYERSGVLHGLMRVRSFTQDDAHIFCTPDQIEDEILGVLELINTIYSQFGFTYRVELSTMPEDHMGDEAIWEKATNALKKALDRAGLPYRVNEGEGAFYGPKIDFHIKDSLGREWQCATIQLDFMMPEKFNVTYIGPDNREHTAVMIHRAIYGSLERFFGILIEHFAGAFPTWIAPVQVAVIPISDKHSEGAKKVATMLSREGFRVFLDDRRETLGYRIRQAQIQKIPYMVVLGDRELESGKLSVRTRSGKEIKDVEMDHFIDTLKKEVRDRKLELTLEG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_TROWT
Sequence: MCVYIVAGLGNPGPSYDKTRHNVGQMVLDILSGGARFRRHKTNNFYLSLGDILLVKPDAYMNLSGPVIASLMKFHSVSDLLVLHDDIDLPLGTLRFKQGGGTAGHRGLRSISDCLGSDYARLRVGIGRPENNQSIEDFVLSNFSPVQTDIISRTIQLAAEAVLHLRDNGFVGVKQFIAQTKLPSRT
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODA_RHILV
Sequence: MSSEVRWKICWENELEASDHAELADFFCKTYGPTGAFNAKPFETGRSWGGARPERRAIAYDSHGVASHMGLLRRFIKVGTTDLLVAELGLYGVRPDLEGLGIAHSVRAMFPILRELSVPFAFGTVRHAMRNHMERYCRDGTANIMTGLRVRSTLPDAHSDLPATRTEDVLVLVVPVDRPMTEWPAGSLIERNGSEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts (By similarity).
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_KLEP3
Sequence: MTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYVEHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_PSEAE
Sequence: MDNALVRLTQVGVSFNGQAVLSDVDLAIEPGQIVTLIGPNGAGKTTLVRSVLGLLKPHVGEVWRRPRLTIGYMPQKLHVDATLPLSVLRFLRLVPGVKREQALAALREVGAAHVLERPLQSISGGELQRVLLARALLRKPELLVLDEPVQGVDVAGQAELYRLIGKLRDRYGCGVLMVSHDLHLVMSATDQVVCLNRHVCCSGHPEQVSGDPAFVELFGQDARSLAIYHHHHDHAHDLHGEVVKAGPGALPPGTRFTPVHKHGPDCNHG
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSD_BURCM
Sequence: MNYPHPIIAREGWPFIAIAAVIALLIHAVGGFGFAWPFWLLLVFVVQFFRDPQRPIPAQPNAVLCPADGRIVAVETTQDPYANREALKISVFMNVFNVHSQRSPVDGAVTKVEYFPGAFLNAAIDKASTENERNALVIQTASGKTVTAVQIAGLVARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPLGSRAKVSIGEKVYASSTILAELEQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CH60_SOLUE
Sequence: MAKQIVYSEASRQAILRGVNQLADAVKVTLGPKGRNVVLEKKFGGPTITKDGVTVAKEIELKDPLENMGAQMVREVASKTSDVAGDGTTTATILAQSIYREGVKAVAAGANPMALKRGIDKAVELATEEVKKLSKPVSGDMIAQVGTISANSDKTIGNIIADAMKKVGKDGVITVEESKTMVTELDTVEGMQFDRGYLSPYFVSDAERMEAVLEDPYILIHEKKISNMKDLLPLLEQIARSGKPLLIIAEEVEGEALATLVVNKLRGTLNACAVKAPGFGDRRKAMLEDIGILTGGKPIMEDIGVKLEGVRLEDLGRAKRVTVDKDNTTIVDGAGNPKGIEGRIKQLRAQIDETTSDYDREKLQERLAKLAGGVAVIKVGAATETEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRAAKALATFKVDGDEQIGVSIVKRACEEPLRQIVSNSGTEGAIVVDKVRENANNNYGYNAATDTYEDLVAAGVIDPTKVTRSALQHAASIAGLMLTTEAMIAEIPEKKSAPAGGPGGHGPEMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KI18B_RAT
Sequence: MVMAVEDSVVRVVVRVRPPTPKELESQRRPVIQVVDERMLVFDPEECDGGFPGLKWSGSLSGPKKKGKDLTFVFDRVFSEVATQQDVFQHTTHNILDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIMYLTTMELYRRLEACQEEKQFEVLISYLEVYNEQIYDLLEPKGPLTIREDPDKGVVVPGLSFHQPASAQQLLEMLTRGNCSRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQALRVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKSHVPYRDSKLTRLLKDSIGGNCRTVMIAAVSPSSLTYEDTYNTLKYADRAKEIRLTLKSNVISLDHHISQYATICQQLQAEVAALREKLQTYEAGAQALQQRSPQPPKLSIPQNLSSSPLQPGHSSQSCAPEFHAKYDAPQEESLGTDSQGQGTVEENAPEQEQPPQDKQFPTQMPEPNLPGSPCPTVQAKQGMNQHSLQRLDAEHSKQLALRVLRLAQRQYSLLQAANLLTPDMISEFETLQQLVLEESMEHGAESPRSPGLARGIPLAQELCSESKSSRYCGPVTRTMAKQLSGLTHTLGIPLAPDCTSDKTSQKPTKEKKRKLNLEEPGSLPAPSVEMKRQRQSFLPCLRRGSLPKIQPSSEPRTPKGERASSPSPSSRVCPATVIKSRVPLGPSALQNCSTPLTLPTRDLNTTFNVSEESPSKPSFPEPIDWEKVSPELNGTDQPFLPSAPVFIFTTKGRKPSLPTTTASKKRRTVRPSVSRGRSCIARLPSSTLKKPDRPFTVPDPPLSLHCLDDHQVIRD
What is the function of this protein?
In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.  Its major role may be to transport KIF2C and/or MAPRE1 along microtubules (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF18B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Present predominantly in the nucleus and to a lesser extent in the cytoplasm of interphase cells. During mitosis, found to be closely associated with astral microtubule plus ends emanating from the spindle pole during prometaphase and metaphase (By similarity).
Protein: PDXJ_SYNC1
Sequence: MALLGVNVDHVATIRQARGTNEPDPVTAAALAELAGADGITIHLREDRRHIQDRDVELIRQTVKTRLNLEMAATDEMVGIALKVRPDAVTLVPEKRKELTTEGGLNVALLRQTLKKHIDLLKQGGISVSLFIDPDLEQVKASHRIGADAIEIHTGAYCDAACAATRSKELDKLTNAVKAGNKLGLLVHAGHGLTYFNIQPVAAIGGIREFNIGHSIISRAVLVGMDRAVREMKDLVGGA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTP1_FOWPN
Sequence: MNTYAAYIDYALKKLDTFPVDMTGGNDNTVLLKDYQLFVAKVFLGLNSMNSILLFQETGVGKTITTVYMLKNLKKIYSEWTIIILVKKALIDDPWTHTILDYAPEVMKDCIIMNYDDQNFHNKFFTNIKSINVKSRIFIIIDECHNFISKSLTKEDNKKRNTKLVYNYIAKNLMQKNNKLICLSATPIVNDVREFQMLVNLLRPGILTPDKSLFYNKKLIDEKEIISKLGCICSYIVNNEASIFEDVENTTLFAKKTVHIKHVFMSKKQEELYLKARYLERKLGISVFKIYQRMASTFVFDDIPDKKKLTEEEYEKFVDSLSIDFKNTLYGKKISKQSLDILSAGGTINDIKDVKDIELYNYLYEHSCKFTFVCVSIIQSKGKCLVFEPFIRSSGIEILLQYFNVFGITYIEFSSRTKDIRSKSVSDFNKVDNTDGEITKVCVFSQSGNEGISFLSINDIFILDMTWNEASLKQIIGRAIRLNSHVNNPPERRYVNVYFVVAKLSSGRSSVDDILLDIIQSKSKEFSQLYKVFKHSSIEWIYSNYTDFQTVDDEKGFKKLISRNIILDENTITNKKKLTMGENIWYSFSSSLVSIHRGFKSMDNKIYDSEGFFITVLPDKPTIKIYEGKLIYILTVR
What is the function of this protein?
DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts.  Acts in concert with the RAP94 subunit of the virion RNA polymerase and the capping enzyme/VTF to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex.  NPH-I must bind ssDNA in order to exhibit ATPase activity (By similarity).
What are the official names of this protein?
Nucleoside triphosphatase I, NPH-I, Nucleoside triphosphate phosphohydrolase I, NPH I.
What is the protein family that this protein belongs to?
Belongs to the helicase family. NPH I subfamily.
What are the subcellular locations of this protein?
Virion. Note=Virion core enzyme.
Protein: ENT3_ARATH
Sequence: MADRYENQPPEKLQGKYQAMVVCCILGIGSLVSWNSMLTIADYYYKVFPDYHPSRVLTLVYQPFALGTILILAYHESKINTRKRNLIGYILFTISTFLLIVLDLATKGRGGIGPYIGLCAVVASFGLADATVQGGMIGDLSLMCPELVQSFMGGLAVSGALTSALRLITKAAFEKTNDGPRKGAMMFLAISTCIELLCVFLYAYVFPKLPIVKYYRRKAASEGSKTVSADLAAAGIQNQSDLTDDDSKNQRLSNKELLIQNIDYAVNLFLIYVCTLSIFPGFLYENTGQHGLGDWYALVLVAMYNCWDLVGRYTPLVKWLKIENRKLITIAVLSRYLLIPAFYFTAKYGDQGWMIMLISVLGLTNGHLTVCIMTIAPKGYKGPEQNALGNLLVIFLLGGIFAGVALDWLWLIGKKNAF
What is the function of this protein?
Nucleoside transporter that functions as a pyrimidine nucleoside carrier in all organs.  Has high affinity for adenosine and uridine when expressed in a heterologous system (yeast).  Mediates proton-dependent adenosine or uridine transport in Xenopus oocytes.
What are the official names of this protein?
Equilibrative nucleotide transporter 3, AtENT3, Nucleoside transporter ENT3, Protein FLUOROURIDINE RESISTANT 1.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: SP17_MACFA
Sequence: MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFESLLEKREKTNFDPAEWGSKVEDRFYNNHAFEEQEPPEKSDPKQEESQIPGKEEEASVTILDSSEEDKEKEEVAAVKIQAAFRGHVAREEVKKMKTDSLQNEEKEENK
What is the function of this protein?
Sperm surface zona pellucida binding protein.  Helps to bind spermatozoa to the zona pellucida with high affinity.  Might function in binding zona pellucida and carbohydrates (By similarity).
What are the official names of this protein?
Sperm surface protein Sp17, Sperm autoantigenic protein 17.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: MCC08_ARATH
Sequence: MENHEQTSFTFEIDNFLEKGDAISPIFISGGCEWFIRVWQIEDHLAVTLSVPNLESLRYGWERRTKYSFIVLNQSGRELERTFEVEGLFCTELLEWCHPKVMPTNKLQEVCLENNKLIIEVQVKVLEVVHEGGVTTEKEMFNIEGFDVLYTQVSRVSWLFVEHPNIAVDVRIKNQLVRTAYINVLLGLIETLDRSPRSLSETDLRDAHIELSELTEAGFKVDWLKKKLEEVSLARKNDISDGSQVEELEEHVKNLKLELDNEKIKSSTASERVLLLEKEVLDLKIELDRTRRGQPNLLYLKLRY
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At2g42470, RTM3-like protein At2g42470.
Protein: RL6_SALAR
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHVDNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL333_STAAN
Sequence: MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHKESK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: WAG31_MYCBO
Sequence: MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLRQRINELDQELAAGGGAGVTPQATQAIPAYEPEPGKPAPAAVSAGMNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADARANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADALQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSNADAGGFDQFNRGKN
What is the function of this protein?
Important for maintaining cell shape and cell wall integrity by localizing peptidoglycan synthesis to the cell poles.
What are the official names of this protein?
Cell wall synthesis protein Wag31, Antigen 84.
What is the protein family that this protein belongs to?
Belongs to the DivIVA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell poles.