PharMolix/UniProtQA huggingface dataset:
Protein: Y524_METJA
Sequence: MRWVIMKKLGKIWNYLSKPEIVPRIFSVFLALVFIFGLLMPHYLNPNQLYPKPIPHSQTLKTPLAPYDRGGIPLKEPAELKAQYPQYEPNLGKITAYLTPIAEWIKDKTYYFGTTIVSTPGGILDEILYYTRGMDTVLESSILLISFIIFSWLFFNKD
What are the official names of this protein?
Uncharacterized protein MJ0524.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 032R_IIV3
Sequence: MKLMLEIVKNISEPVGKLAIWFNETYQVDVSETINKWNELTGMNITVQENAVSADDTTAEETEYSVVVNENPTRTAARTRKESKTAAKPRKMQIPKTKDVCQHIFKSGSRAGEQCTTKPKNNALFCSAHRVRNSVTSNATEASEKTVAKTNGTAAPQKRGVKSKSPTVIPSDFDDSDSSSSATRGLRKAPTLSPRKPPPTTTTASSAQEEEDEQQAHFSGSSSPPPKNNGNGAVYSDSSSDEDDDDAHHTTVIPLLKKGARKPLDENVQFTSDSSDEED
What are the official names of this protein?
Uncharacterized protein 032R.
Protein: RS18_SORC5
Sequence: MNGRNNDMGRNGGADYDDRDFGRTPDLNADAPGRRRTGRKRVCRYCADKALVIDYKDPQALKYFISERGKVVPRRISGNCARHQRKVTLSIKRARNIALLPFTVTA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HEM2_METJA
Sequence: MFKINLGDFMLIRPRRLRKNQKIRDLVRETILTKNDLIMPIFVDENLKGNEKKEISSMPNQYRFSVEGAIEEAKEIADLGIPAVILFGIPKHKDEIASSAYDKNGVVQRTIRGIKEELGDELLVIADCCLCEYTSHGHCGIVKDGKILNDATLPILAKIALSYADAGVDIVAPSDMMDGRVRAIREILEENGYDDVAIMSYSAKYASSFYGPFREAAESAPKFGDRKSYQMDIGNAREALKEIALDIEEGADLILVKPALPYLDIIRMAKDRFDVPIGGYCVSGEYAMVEAAARNGWLDREKVIYEILLSIKRAGADFIITYWAKEVAEIGLSQE
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: CFM6_MARBU
Sequence: MKYSMITLGAFAMMAVAQLSSLPACGQTCISNMLALAPTFGCTANDASCLCSDVNFAYGIRDCSNAACGAEAAGPVIAYGVEYCSSAGVGLSGSATGIDPGLGPATAVVASTPIATDGASAGSLSAITTSEFTSYVISGDSTVSTIVGSTTIYGPAAGSSSAITTSPIVSTVTSGDTSYPTTVGSTTIFGVAGVISTPTASASSALDSLSSSIASEASVITSSASAAVSSLSSRLSSAASPVSTTTSSAGGARQTAFAGLAAAAGFAAIIL
What is the function of this protein?
Appears to function during host infection, and may play a role in suppressing the host immune response.
What are the official names of this protein?
Effector CFEM6, MbCFEM6.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: YMF32_MARPO
Sequence: MSEIAKWLNTRFQLTLIPKENSNTEFVGPCIFREDGDNTKLFGFRTTLFYTYIGMQTCLLSE
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf32, ORF62.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y108_AFV1Y
Sequence: MEQRFTHEDRFIMGLFPLLAVILISSNSSIIDIAMTVIIFGWIIYETLITVHFCKNYIETVESIMLGFVGFLGVLCLDKFPFGIILLIIYVIEGIYINVKTLKYARSC
What are the official names of this protein?
Putative transmembrane protein ORF108.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: CARD_MYCS2
Sequence: MIFKVGDTVVYPHHGAALIEAIETRTIKGEQKEYLVLKVAQGDLTVRVPADNAEYVGVRDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGELALAENTDDAKAETILDEVLAAAS
What is the function of this protein?
Controls rRNA transcription by binding to the RNA polymerase (RNAP).  Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions.
What are the official names of this protein?
RNA polymerase-binding transcription factor CarD.
What is the protein family that this protein belongs to?
Belongs to the CarD family.
Protein: RL4_CAMHC
Sequence: MSKVKVLNEKLEKASELELPANFADVNPHNLYLYVKSYLASLRANTANTKGRSEVSGGGKKPWRQKGRGGARAGSTRTNVWVGGAVAFGPTNNRNYFQKVNKKQKRLALEFALNEKAQNDKIFAVDSLEISSGKTKDAAKFIKNLGVRDALIVKNELDSATLLAYRNLNNCYVIDINELNAYLVAVYSAVIIETSALQSIVKEG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ATPD_XYLFT
Sequence: MIQALTLARPYARAAFAIACEKGKCMQWSQALTFSAQVANNPIVATLLSHPQLDHEQAAALLSPEGADPAYIRFLEVIAEAHRLDVLLQVAGLYEKLRAEAQHVIKAKITSAIELAPNELNNIVTALKKRFDCEIEVTTGVDHSLIGGAVIDTGNVVIDGSIKSKLTRLQASLTH
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y4520_MYCUA
Sequence: MHGTDSSSDTPGQPAPSRAELLSAHAEGSISEDTILKTARDRAVDIGVGAVTPAVGALLSMLAKLSGGKAVAEVGTGAGVSGLWLLSGMSDDGVLTTIDIEPEHLRVAKQAFTEAGIGPSRTRLISGRAQEVLTRLADDSYDLVFVDADPIDQPDYVVEGVRLLRSGGVIVVHRAALGDRAGDPAVRDAEVTAVREAARLIAEDERLTPALVPLGDGVLAAVRD
What are the official names of this protein?
Putative O-methyltransferase MUL_4520.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: YJBE_ECOLI
Sequence: MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSATSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ
What are the official names of this protein?
Uncharacterized protein YjbE.
Protein: PDR_BURCE
Sequence: MTTPQEDGFLRLKIASKEKIARDIWSFELTDPQGAPLPPFEAGANLTVAVPNGSRRTYSLCNDSQERNRYVIAVKRDSNGRGGSISFIDDTSEGDAVEVSLPRNEFPLDKRAKSFILVAGGIGITPMLSMARQLRAEGLRSFRLYYLTRDPEGTAFFDELTSDEWRSDVKIHHDHGDPTKAFDFWSVFEKSKPAQHVYCCGPQALMDTVRDMTGHWPSGTVHFESFGATNTNARENTPFTVRLSRSGTSFEIPANRSILEVLRDANVRVPSSCESGTCGSCKTALCSGEADHRDMVLRDDEKGTQIMVCVSRAKSAELVLDL
What is the function of this protein?
Component of the electron transfer chain involved in pyridine nucleotide-dependent dihydroxylation of phthalate.  Utilizes FMN to mediate electron transfer from the two-electron donor, NADH, to the one-electron acceptor, (2Fe-2S).
What are the official names of this protein?
Phthalate dioxygenase reductase, PDR.
What is the protein family that this protein belongs to?
Belongs to the PDR/VanB family.
Protein: PRL_LOXAF
Sequence: IPVCPRGSVRCQVSLPDLFDRAVMLSHYIHSLSSDMFHEFNKQYALGRGFIPRAINSCHTSSISTPEDKDQAQQTHHEVLMDLILGLLRSWNDPLDHLASEVHSLPKAPSALLTKATEVKEENQRLLEGIEKIVDQVHPGAKENKAYSVWSGLPSLQTTDEDARLFAFYNLFRCLRRDSHKIDSYLKLLKCRIVYNNNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSB_BACCR
Sequence: MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTRNYEGQDGKRVYVTEVLAESVQFLEPRNGGGEQRGSFNQQPSGAGFGNQGSNPFGQSSNSGNQGNSGFTKNDDPFSNVGQPIDISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: Y019_SIFVH
Sequence: MNEQINEQIEFGEKYVKINDKFFYMSTENVEFIQWWYERFGHIKGIQFMEKLVKLFIIAKPEDYNDQWYVLDILKKHEKEISPLINLIYSNYEK
What are the official names of this protein?
Uncharacterized protein 19.
Protein: PMP1_PARBF
Sequence: MLQIRVFNYNDPIDGENIVELRYHNRSPVKAFQIVDGIWIIPERYNFTNDTKKVPDDRALTILEDEVFAVRENDYLTTDVNEKNSFLNNITKLFKRINSSNIGNQLLNYISTSVPYPVVSTNSIKARDYNTIKFDSIDGRRITKSANVLIYGPSMKNLLDKQTRAINGEEAKNGIGCLSDIIFSPNYLSVQTVSSSRFVEDPASSLTHELIHALHNLYGIQYPGEEKFKFGGFIDKLLGTRECIDYEEVLTYGGKDSEIIRKKIDKSLYPDDFVNKYGEMYKRIKGSNPYYPDEKKLKQSFLNRMNPFDQNGTFDTKEFKNHLMDLWFGLNESEFAKEKKILVRKHYITKQINPKYTELTNDVYTEDKGFVNGQSIDNQNFKIIDDLISKKVKLCSITSKNRVNICIDVNKEDLYFISDKEGFENIDFSEPEIRYDSNVTTATTSSFTDHFLVNRTFNDSDRFPPVELEYAIEPAEIVDNTIMPDIDQKSEISLDNLTTFHYLNAQKMDLGFDSSKEQLKMVTSIEESLLDSKKVYTPFTRTAHSVNERISGIAESYLFYQWLKTVINDFTDELNQKSNTDKVADISWIIPYVGPALNIGLDLSHGDFTKAFEDLGVSILFAIAPEFATISLVALSIYENIEEDSQKEKVINKVENTLARRIEKWHQVYAFMVAQWWGMVHTQIDTRIHQMYESLSHQIIAIKANMEYQLSHYKGPDNDKLLLKDYIYEAEIALNTSANRAMKNIERFMIESSISYLKNNLIPSVVENLKKFDADTKKNLDQFIDKNSSVLGSDLHILKSQVDLELNPTTKVAFNIQSIPDFDINALIDRLGIQLKDNLVFSLGVESDKIKDLSGNNTNLEVKTGVQIVDGRDSKTIRLNSNENSSIIVQKNESINFSYFSDFTISFWIRVPRLNKNDFIDLGIEYDLVNNMDNQGWKISLKDGNLVWRMKDRFGKIIDIITSLTFSNSFIDKYISSNIWRHITITVNQLKDCTLYINGDKIDSKSINELRGIDNNSPIIFKLEGNRNKNQFIRLDQFNIYQRALNESEVEMLFNSYFNSNILRDFWGEPLEYNKSYYMINQAILGGPLRSTYKSWYGEYYPYISRMRTFNVSSFILIPYLYHKGSDVEKVKIINKNNVDKYVRKNDVADVKFENYGNLILTLPMYSKIKERYMVLNEGRNGDLKLIQLQSNDKYYCQIRIFEMYRNGLLSIADDENWLYSSGWYLYSSGWYLDNYKTLDLKKHTKTNWYFVSEDEGWKE
What is the function of this protein?
Responsible for host epithelial cell transcytosis, host nerve cell targeting and translocation of PMP1 light chain (LC) into host cytosol.  Composed of 3 subdomains; the translocation domain (TD), and N-terminus and C-terminus of the receptor-binding domain (RBD), called HCN and HCC.
What are the official names of this protein?
Paraclostridial mosquitocidal protein 1, PMP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M27 family.
Protein: ENV_HV1MV
Sequence: MTVTMKVMKKNNRKSWSLYIAMALLIPCLSYSKQLYATVYSGVPVWEEAAPVLFCASDANLTSTEQHNIWASQACVPTDPNPHEFPLGNVTDNFDIWKNYMVDQMHEDIISLWEQSLKPCEKMTFLCVQMNCVDLQTNKTGLLNETINEMRNCSFNVTTVLTDKKEQKQALFYVSDLSKVNDSNAVNGTTYMLTNCNSTIIKQACPKVSFEPIPIHYCAPTGYAIFKCNDTDFNGTGLCHNISVVTCTHGIKPTVSTQLILNGTLSREKIRIMGKNITESAKNIIVTLNTPINMTCIREGIAEVQDIYTGPMRWRSMTLKRSNNTSPRSRVAYCTYNKTVWENALQQTAIRYLNLVNQTENVTIIFSRTSGGDAEVSHLHFNCHGEFFYCNTSGMFNYTFINCTKSGCQEIKGSNETNKNGTIPCKLRQLVRSWMKGESRIYAPPIPGNLTCHSNITGMILQLDQPWNSTGENTLRPVGGDMKDIWRTKLYNYKVVQIKPFSVAPTKMSRPIINIHTPHREKRAVGLGMLFLGVLSAAGSTMGAAATALTVRTHSVLKGIVQQQDNLLRAIQAQQHLLRLSVWGIRQLRARLQALETLIQNQQRLNLWGCKGKLICYTSVKWNTSWSGRYNDDSIWDNLTWQQWDQHINNVSSIIYDEIQAAQDQQEKNVKALLELDEWASLWNWFDITKWLWYIKIAIIIVGALIGIRVIMIILNLVKNIRQGYQPLSLQIPVPHRQEAETPGRTGEEGGEGDRPKWTALPPGFLQQLYTDLRTIILWTYHLLSNLISGIRRLIDYLGLGLWILGQKTIEACRLCGAVMQYWLQELKNSATNLLDTIAVSVANWTDGIILGLQRIGQGFLHIPRRIRQGAERILV
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: Y2399_VIBCM
Sequence: MSKNRLPAYPALANELRSASLGINPAELQGLLTGMLSGGLSLNDKSWQALVFDYTNDGMGWPIGALASAEQILLAMSAQLVDTDFELSLLLPEGEGEEALFELADAVAEWINHFISGLGLSGANLKHASVEAKEALEDLEEMSKLGIDEEDDLAEQAELLEQVIEHIKACVLVLHAEFGVKPEQDTKPTVH
What are the official names of this protein?
UPF0149 protein VCM66_2399.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: VATB2_CAEEL
Sequence: MTEASEINLSDIKGPIDVNTPITNHRTALIQNYSTKPKLTYQTVFGVNGPLVIVHNVKFPMFNEIVKITLPNGQIRMGQVLESSKNKAVVQVFEGTTGVDAKFTTCEFTGDIFRSPVSLDMLGRIFNGSGKPIDKGPPVLPEDYLDINGQPINPFNRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQIVRQGGLVQLPGRNNETVNFAIVFAAMGVNMETARFFKQDFEECGSMDNVCLFLNLANDPTIERIITPRIALTAAEFFAYHCGKHVLVVLTDMSSYAEALREISAAREEVPGRRGFPGYMYTDLATIYERAGRVKGREGSITQIPILTMPNNDITHPIPDLTGYITEGQIYIDKQLHKRLIYPPIDVLPSLSRLMKSAVGEGMTREDHSDLSNQLYACYAMGKDVQAMKAVVGVEALSPDDLLYLEFLAKFEKNFIAQGRYENRTIVESLNIGWELLRIFPREMLKRIPETLLEKYYKRKKQ
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (Probable).  In neurons, required for necrotic cell death probably by promoting intracellular acidification (PubMed:16005300).  Required for spermatogenesis where it regulates the fibrous body-membranous organelle (FBMO) morphology in spermatocytes and the acidification of FBMO-derived secretory membranous organelles (MOs) as spermatids mature (PubMed:9178007, PubMed:22446317).
What are the official names of this protein?
V-type proton ATPase subunit B 2, V-ATPase subunit B 2, Defective spermatogenesis protein 5, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In spermatocytes at the meiotic I stage, localizes to the cytoplasm and to discrete dots (PubMed:22446317). In spermatids and the residual body, localizes to discrete dots in the cytoplasm (PubMed:22446317). In budded spermatids, localizes near the cell membrane as discrete dots that are adjacent to secretory membranous organelles (MOs) (PubMed:22446317).
Protein: DML1_DEBHA
Sequence: MSEVINLSLSQRANHLSAHLYNNQEAHLPYSKTATVDYDNSVFLSTSKNPNGTVNYSPRSLNYDLTRGYGSLGKYEYYESKADILGQYEVIQTGEKMDKNEYQKALDKGMNKSNTLNVNNTKYWTDYNKLIYSPKSLNQLNNWEYKPHDFGINRSFPNLKFDTFNKGKEEYHQYSEDSLENFRNTLEQCDLIQGVNLISELDSAWGGFTNELLVDLKDEFFNNGINSKYNIWVHGLINHNLNPKLNQLYSRINSIIELSFNSTLFFPMNLNSSSECLGVKMSVIEDELLRGFDKRNIVNEIKIHKNKQASNDFGMVDIDRANLYNLVDNIKIKDKPDSIDLSLSDSKNSKYFAKSYIIPNDQSLAESLNKKENFPINIYKNNRINDILNNDTFPNILEDKSVYSEFSSSNTLKNDLKFYREVIKRSRENEVIEDKFELIEKISELIEEYTIGYDESDEEYDSN
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y055B_MYCGE
Sequence: MKVFKKLHNLNEILLLISIFFLVCIISLVGIGIIFDLIRKASLSAIRSDPIFFNLRAVLIVLGVFAICFMIIQLVISIMIWKTINTACENIEPKFKKILHWSCFLPFGLLQLYCYQKIKLVKQADNL
What are the official names of this protein?
Uncharacterized protein MG055.2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VATA_METLZ
Sequence: MEVNSKPGILKRIAGPVVTAVDLDAHMYDVVKVGNEELMGEVIKIDGADTVIQVYESTTGIRPGEPVINTGLSLAVELGPGLLTSIYDGIQRPLEVLIQKMGNFIARGVTAPGLDHEKKWTFKPVVHVGDNVVPGQIVGEVQETRSIVHKIMVPPLAKGGKVTKINAGDFTVDEIVIELDSGESFPMMQKWPVRVPRPYVEKHSPSIPLLTGQRILDGLFPIAKGGTAAIPGPFGSGKTVTQQQLAKWSDAEIVVYIGCGERGNEMTEVLTEFPELQDPKTGNSLMERTILIANTSNMPVAAREASVYTGITLAEYFRDMGYDVALMADSTSRWAEAMREICSRLEEMPGEEGYPAYLSSRLSEFYERAGLVEPLAGGSGSVSVIGAVSPAGGDFSEPVTQNTLRIVKVFWALDANLSRRRHFPAINWLQSYSLYMAQLNDYYDEKVSPDWNKLRSWFMEVLQKEAELQEIVQLVGSDALPETEQITIEVARMMRELFLQQNGFDPVDTYCDLPKQLDMFKMIRTYADLAYAAQAAGVPPSQILAVKAKNEMPQVKFTKDYKPVLDKIYAGMEAEFKALRA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: YCF48_PARMW
Sequence: MTRFVSSAINLLLVLVLGVSLSGCVTTRLPVASTSPWQALNLDTEANPLDVAFTDSRHGYLVGSNRMIRETNDGGATWNDRSLDLPEEENFRLISIDFNGDEGWIAGQPGLLMHTSDGGQNWTRLFLDTKLPGEPYLITALGSHSAEMATNVGAVYETHDDGGSWEALVTDAAGAVRDLRRGDDGSYVSVSSLGNFYATWQPGDSVWQVHQRVSSQRLQSIGYQPDGNLWMVARGAQIRLNDESGNLESWTKAIIPITNGYGYMDMAWDEDGAIWAGGGNGTLLVSRDGADSWEIDPVGDRQPSNFTRMVFDWDHAFVLGERGNLLRWVGNAV
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: SEPP1_BOVIN
Sequence: MWRGLGLALALCLLLTGGTESQGQSSYCKQPPPWSIKDQDPMLNSYGSVTVVALLQASUYLCILQASRLEDLRVKLEKEGYSNISYVVVNHQGISSRLKYVHLKNKVSEHIPVYQQEENQPDVWTLLNGNKDDFLIYDRCGRLVYHLGLPYSFLTFTYVEDSIKTVYCEDKCGNCSLKALEDEDVCKNVFLATKEKTAEASQRHHHPHPHSHPHPHPHPHPHPHPHPHHGHQLHENAHLSESPKPDTPDTPENPPPSGLHHHHHRHKGPQRQGHSDNCDTPVGSESLQPSLPQKKLURKRCINQLLUQFPKDSESALSSCCCHCRHLVFEKTGSAITUQCTEKLPSLCSUQGLLAEENVIESUQURLPPAAUQAAGQQLNPTEASTKUSUKNKAKMUKUPSN
What is the function of this protein?
Constitutes a major selenium pool in the brain and may play an important role in developing and/or modulating the morphology of neurons and/or glial cells.
What are the official names of this protein?
Selenoprotein P, SeP, Selenoprotein P-like protein.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein P family.
What are the subcellular locations of this protein?
Secreted. Note=Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium.
Protein: PURA_MYCTU
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGVLTPGVTNVIGNGVVIDPGVLLNELRGLQDRGVDTAKLLISADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVADVLDPEQLTHKVEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHRIADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAVGSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVTTGRRRRCGWFDAVIARYAARVNGITDYFLTKLDVLSSLESVPVCVGYEIDGRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMRE_AEDAE
Sequence: MVLSNVVRVVNRLNSAGTRSGLMGIRQLRRKYTYRSGALKPMPNVIPFGLLGVVLTVIPGLLIGATISKNMANFLEENDLFVPSDDDDDDD
What is the function of this protein?
Essential regulatory subunit of the mitochondrial calcium uniporter (mcu) channel, a protein that mediates calcium uptake into mitochondria.
What are the official names of this protein?
Essential MCU regulator, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SMDT1/EMRE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PIN2_YEAST
Sequence: MNVCKLKEIVPLFPRSSFTDGVVSTGKSFRSWDTCMDNKACKIIAIVGIVLACILVIWLIGGLLTCFRQGVTGIGQFICWCCRCSNDRNGNNTMPVNEGFSRVNMGVAPPSTVIYQPIQQPESAYYRNDAKNDTFYDEVKTPSNEVYELEEDFDLEKQKEKTRKKQQKERNKEGRSPSRVAPLVYEEENFEGSSPQPQYDARNSFIQNAANTGSNNAHVASQSPIFDISDYGENYYYDNNNINNNLQGNSYNTPSSNHRSPYPTENYQSYQGYKPNQSDRYY
What is the function of this protein?
Not known.  Seems to be able to provoque the non-Mendelian trait [PIN(+)] which is required for the de novo appearance of the [PSI(+)] prion.
What are the official names of this protein?
[PSI+] induction protein 2.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: HIS4_METB6
Sequence: MRIFPAVDILGGRCVQLVQGKRESATAYGDPLTCARRWIDAGADALHVVNLDGAFGDSAKNADLIRGLVKETGIEIELGGGIRSVEDAARWLDTGASRIILSTFAIKEPESIRTLSQEFGSDRVMAGVDAKGGQVAIHGWQETAGDYIGWAQRFEQLGAGFLLYTNVDVEGLQGGIAAGPVRRLIGNVRIPVVVAGGVSARADVALLKESGAYGAVLGSALYSGKINLSEALEESR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_EBLV2
Sequence: MSKIFVNPSAIRAGLADLEMAEETVDLVNKNIEDNQAHLQGEPIEVDALPEDMSKLQISERRPAQFTDNTGGKEEGSDEDFYMAESEDPYIPLQSYLEGVGIQLVRQMKTGERFFKIWSQAVEEIISYVTVHFPMPLGKSTEDKSTQTPEEKFKPSPQQAVTKKESQSSKIKTISQESSGPPALEWSTTNDEENASVEAEIAHQIAESFSKKYKFPSRSSGIFLFNFEQLKMNLDDIVKEAKKIPGVVRLAQDGFRLPLRCILGGVGSVNSKKFQLLVNSDKLGKIMQDDLNRYLAY
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA.  Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus protein P family.
What are the subcellular locations of this protein?
[Phosphoprotein]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P2]: Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P3]: Host nucleus. SUBCELLULAR LOCATION: [Isoform P5]: Host nucleus.
Protein: CSRA_HELPG
Sequence: MLILSRKVNEGIVIDDNIHIKVISIDRGSVRLGFEAPESTLILRAELKEAIVSENQKASASVDESVLENIKKVIKP
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH73A_YEAST
Sequence: MDRIIRGKRDHILHCPLAAYSSNPRKYPYVKNSLRQDSLWSRGSATFPVTLWSKVILK
What are the official names of this protein?
Uncharacterized protein YHR073W-A.