PharMolix/UniProtQA huggingface dataset:
Protein: PSAB_SYNJA
Sequence: MATTATRFPQFSQDLASDPTTRRLWYGIATAHDFETHDGMTEERLYQKLFATHFGHLAIIFLWASGNVFHIAWQGNYEQWVANPTGVTPIAHAIWDPQFGKAAVEAFTQPGGGGPVNAAYSGLYYWFNTIGLRTNGDLYAGAIGLLLLAAVFLFAGWLHLQPRFRPSLSWFKNAEARLNHHLAGLFGVSSLAWAGHLVHVAIPESRGQHVGWDNFLTTLPHPAGLKPFFTLNWGVYAQNPDTANHVWGTAEGAGTAILTFLGGFNPNTQSLWLTDMAHHHLAIAVIFIVAGHMYRTNWGIGHSIREILGAHNPPKGTPFGGLLGEGHRGLYDTVNNSLHFQLALALACLGVVTSLVAQHMYALNPYVFMSMDHTTEAALYTHHQYIAGFLMVGAFAHGAIFLVRDYDPEANKNNVLARVLDHKEAIISHLSWVSLFLGFHTLGLYVHNDVMQAFGTPEKQILIEPVFAQFIQASHGKMIYGMDVLLSNPDSIASTAWPNYGNVWLPGWLQAINDPNGFLFLPIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAMFWMLNTIGWVTFYWHWKHLGIWSGNTAQFNENSTYLMGWLRDYLWANSAQLINGYNPYGMNNLAVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPLANLIRWKDKPVALSIVQGRLVGLAHFTVGYVLTYAAFVIASTASLSG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: DAPA_METKA
Sequence: MGFQIEGVIPALITPFTDDLKGINEEGLRENVSRLLEAGVHGVVPAGTTGESSTLSHAEHRRVIEIVVDEVNGKVPVIAGAGSNSTREALELSTYAEDVGADAILSVVPYYNKPPQEGLFIHFSKIAEAVECPIILYNVPSRTGCALEPETAAKLAEEYSHIVGVKEASGDLDVVQRFIEETPDDFILLSGVDELTLPILAVGGVGVISVTANVAPELMVEMYEAWKSGDVERARELHYELLPLHRALFTETNPIPVKAAVELVGMASSPPRPPLKEAREDTKELLRRELKKLGLLPEGG
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_SALA4
Sequence: MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTPGPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGINQRTTLIKHGFYPAGGGAAATVVEPAASLRGLTLISRGETRRITAEALLASVPHHVGEREVATLEAHFPRAEKNVVALEGGCGPGNALSLMIQSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFLPVTFNLEEAREMVQVMVSKKDSGS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_RUTMC
Sequence: MIQMQTKLKVADNSGGVKAMCIKVLGGSKRRYANIGDVIKVSIKEAASRGKVKKGDVYDAVVVRTAHGVRRSDGSCIRFDNNAIVLLNTKLEPIGTRIFGPVTRELRSAQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LTMD1_MOUSE
Sequence: MALSRVCWARAALWGSTVAPGPFVTRRLQLGRSGPAWRAPRSSKLHLSPKADVKNLISYVVTKTRAINGSYHRFLGRHFPRFYALYTTFMKGIQMLWADGKKARRIKADMWKQNLKFHQLSYREMEHLRQFRRDITKCLFVGLISIPPFANYLVFLLMYLFPRQLLVKHFWTPKQQIDFLDVYHGLRRRSHSEVITHLRRASTFVSHEKLRRQLTDLCTKVQSGTHPAAQDVLALRDCFSTYPLGFSQLQASQMRALSQAMLLTPYLPPPLLRQRLKSHTTVIHQLDRALAKLGIGQLTAQEVKSACYLRGLNSTHIADDRCRAWLGEWLHISCSLKEPELSLLLHNVVLLSTNYLETRR
What is the function of this protein?
Plays an essential role for mitochondrial structure and function, as well as thermogenesis of brown adipocytes (PubMed:34669999, PubMed:34910916, PubMed:36334589).  In brown adipose tissue also localizes in the nucleus where it interacts with the chromatin remodeler SMARCA4 to regulate thermogenic genes expression, such as UCP1 (PubMed:34910916).  May regulate phagocytosis and inflammatory responses to lipopolysaccharide in macrophages (By similarity).  Involved in tumorigenesis and may function as a negative regulator of the p53/TP53 (PubMed:12879013).
What are the official names of this protein?
LETM1 domain-containing protein 1, Cervical cancer receptor, MCC-32.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: Y2415_LEGPH
Sequence: MLYWALIFLIVAIVAGLFGFRGVASAATGIAKVLFFLFIVMFIVLLVFSLLGGTPEPVVIVKP
What are the official names of this protein?
UPF0391 membrane protein lpg2415.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2164_STAS1
Sequence: MKKIMITGALGQIGTELVVKCRTLYGNDNVLATDIREPEEGSALKNGPFEILDVTDKARMDELVESFKPDTMMHMAALLSATAEKNPLFAWDLNMGGLMNALEVAREYKLQFFTPSSIGAFGPSTPKVNTPQVTIQRPTSMYGVNKVAGELLCQYYFEKFGVDTRSVRFPGLISHIKEPGGGTTDYAVDIYFKAVREGQYSSFIAKDTFMDMMFMEDAINAIIQLMEADGVKLINRNAYNLSAMSIEPEMVKEAIQEYYPDFKLDYDVDPVRQSIADSWPNSIDVSCARAEWGFDPQYDLSAMTKVMLDAIEGKEKAEVK
What are the official names of this protein?
Uncharacterized epimerase/dehydratase SSP2164.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: PANB_ACIB3
Sequence: MISLSDLRKFKAEGRKFSCLTCYDASMAKAMELAEIDTILIGDSLGMAIQGRDSTLPVTVEDMAYHTAAVRRGNQHALIMTDLPFMSYATLNDALQNAKTVMQAGAQMIKIEGGAWLSETVQVLTRNGVPVCVHLGLTPQSVHVFGGYKLQARTREAADQLIADCTAVVEAGAAVLLLECVPAQLGQEIAELFPNTPVIGIGAGNATDGQVLVVQDMLGLTFGRVARFVRNFMKEQSGETAILDAFKAFHAAVQDQSFPAKEHTFQVEL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALFL2_ORYSI
Sequence: MEMAAPVSPAPRTVEDIFKDFSGRRAGLVRALTVDVDEFYGFCDPEKENLCLYGHPNGRWEVALPAEEVPPELPEPALGINFARDGMHRRDWLSLVAVHSDSWLLSVAFFFGARLNGNERKRLFSLINDHPTVLEALSDRKHGRDNKSGADNGSKSRHSGKRANDVQTKTSRPAVVDDGYDEEEHSETLCGTCGGRYNANEFWIGCDICERWFHGKCVRITPAKAEHIKHYKCPDCSSSKKSRQ
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 2.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYL1_NEOFI
Sequence: MTTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLSFVELDLKDAHETPKLFDHDVIKGIAQKHGKTPAQVLLRWATQRNIAVIPKSNDPTRLAQNLDVTGWDLETSEIEVISSLNRNLRFNDPLAPSRLDPIPDD
What is the function of this protein?
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable NAD(P)H-dependent D-xylose reductase xyl1, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: TOR_SCHJA
Sequence: MPRASALLTSDPRHQFTCCLCLHVRTGTIIFGITQIIIQLIFISFLFLMTFNPRLFPEDNHGSLDSSQANARYYVLSALFRLVPAVSDIHESLTFPSFPEVRNVNDNKLLFGHNSESEVNFNFDISSGYKDSVPIDMSHSPSRLMSETHKRERGSREIKIRQFSPYIAVCVTTFSLAFCCFMVHGAITRQPTHLLPFFFIQVFDLIICLIHILGFMSSTSDIRLMIHTKTGPIYIKSTGLAFIILSISCMMLAFKAYCLGMVWDCYKYLMLNRRNNVLNEWYSDQWGHFSTFWSLLRAGRNRGNNLTGNLDSANESNTRAHPDPVTYDPSNDLPKYDDILKIPANAYAPPPYYCSNINGNGNLTQANAVTANTTSTNVSTFTTTTTTANTTTNVTSANKNDAEVTSTPSNVHPC
What is the function of this protein?
Cell surface receptor that binds to human complement C2a protein.  This results in inhibition of the classical and lectin pathways of complement activation, probably due to interference with binding of C2a to C4b and interference with cleavage by C1 or MASP2 such that C3 convertase cannot be formed.  This infers resistance to complement-mediated cell lysis, allowing parasite survival and infection (By similarity).
What are the official names of this protein?
Tetraspanning orphan receptor, Complement C2 receptor inhibitor tetraspanning, Complement C2 receptor inhibitor trispanning, Trispanning orphan receptor.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YL064_MIMIV
Sequence: MLKKIGNDLSFFTGYLTFRTYDSIWRKATLPMYSKLKENLRKPTKTCLPQNDLDYRLRHTLIRQNARHYQSIKNTFINIPTFELNTFLKKEFHSNIILASPTLSFSILDYLNDGRIINSDKDIRKIVKKFRLIDSMTRLTDYNAYQLNPAIDILKILDDNTRNKLLGLFDDAIFYSLDIESFVTNFSDKKYYFQDCEAINKQFNYDVYGLYVPYDDNGKKRLQIETIILVDRRTDNTKTYVFQSNFSQWEIIRNNYINWTRTMSSVYEHQLGSNVYCQNTLYHMRKTLAKTHPITVLMKPFMEGVYFTNKVFTSFGISIADTENEVVNRYMDRVELFDLSNQTMIQALEYIHKTDGYKLLDYKKVYHENGVDDIYFEQKQLLEDLYQIVFDLVTNVFEYYYQSTDDYVKDNELRDFYLSIKNDLTFVEDLQQKDNAIKFFSNIIFLSSIRHSKNHINYAYLNSFYDYALRKTNFDLLLDKLDNGIPFDEKDCLSTVGDFYSKYSSGIYPSVPINLFGTGYKNLFADNEVQKFFTDVTNKLNQLKKNTERNNYTEFLFRLQNSNTI
What are the official names of this protein?
Uncharacterized protein L64.
Protein: EFP_AGRVS
Sequence: MVKVIASSVRKGNVLEVDGKLYVVLTAQNFHPGKGTPVTQIDMRRIVDGVKVSERWRTTEQVERAFVEDVNHQFLYEDGEGFHFMNPENYDQIVVDVETMGDQKAYLQEGMTCVISMYEGVALALDLPRHVTLEIMETEPVVKGQTASSSYKPAMLSNGIRTLVPPHINAGTRVVIATEDNSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP2K1_SERCA
Sequence: PIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSPVTETSPRQRAPGRPMSSYGSDSRPPMAIFELLDYIVNEPPPKLPNGVFGSEFQDFVNKCLIKNPAERADLKQLMIHAFIKRSEAEEVDFAGWLCSTIGLNQPSTPTHAAGV
What is the function of this protein?
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.  RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.  Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade.  Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements (By similarity).
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm. Nucleus.
Protein: ATG18_EMENI
Sequence: MTMNFVTFNQDYSYLAVATSKGFRIFTTDPFAKSYETKDGNIAIIEMLFSTSLVALILSPRRLQITNTKRQSTICELTFPTTVLAVKLNRKRLVIVLEDQIYLYDIQTMKLLYTIETSPNPNALCALSPSSENCYLAYPLPQKAAPSSFNPPAHAPPGNTHVSPTSGEVLIFDTLKLEAINVIEAHRSPLACITLNSDGTLIATASDKGTIIRVFSVPDGHKLYQFRRGSIPSRIFSMSFNTTSTLLCVSSSTETIHLFKLSQPSQLQETSSANTSSTGRRRSLSSLSQSPEREATEEDNGSSDLASRKHNGTLMGMLRRTSQNVGGAFAAKVGGYLPKGVSEMWEPARDFAWIKIPKPNQGQGPNANTGPLRSVVAMSSNTPQVMVVTSDGNFYVFSIDLSKGGEGTLTKQYSVLESNDRLGYSVADY
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: TRPC1_RALSO
Sequence: MSDILQKILAVKAEEVAAARKHRDLPSVRAEAEANRHDSTLGPRGFAQALRDKIGAGRAAVIAEVKKASPSKGVLRPDFKPAEIAGSYAEHGAACLSVLTDEQFFQGHADYLREARAACALPALRKDFMVDLYQVYEARSWGADCILLIVSALDQGLMAELEACAHELGMDVLVEVHDGHELERALRLSTPLVGVNNRNLRTFETTLDTTLGLLKHMPDDRIVVTESGILKPDDVRKMRAADVNAFLVGEAFMRADDPGTELARLFA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase 1, IGPS 1.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TETN_HUMAN
Sequence: MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV
What is the function of this protein?
Tetranectin binds to plasminogen and to isolated kringle 4.  May be involved in the packaging of molecules destined for exocytosis.  Plays a role in retinal function (PubMed:35331648).
What are the official names of this protein?
Tetranectin, TN, C-type lectin domain family 3 member B, Plasminogen kringle 4-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CD14_RAT
Sequence: MKLMLGLLLLPLTLVHASPATPEPCELDQDEESVRCYCNFSDPQPNWSSAFLCAGAEDVEFYGGGRSLEYLLKRVDTEANLGQYTDIIRSLPLKRLTVRSARVPTQILFGTLRVLGYSGLRELTLENLEVTGTALSPLLDATGPDLNTLSLRNVSWATTDTWLAELQQWLKPGLKVLSIAQAHSLNFSCKQVGVFPALATLDLSDNPELGEKGLISALCPHKFPTLQVLALRNAGMETTSGVCSALAAARVPLQALDLSHNSLRDTAGTPSCDWPSQLNSLNLSFTGLEHVPKGLPAKLSVLDLSYNRLDRKPRPEELPEVGSLSLTGNPFLHSESQSEAYNSGVVIATALSPGSAGLSGTLALLLGHRLFV
What is the function of this protein?
Coreceptor for bacterial lipopolysaccharide.  In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS).  Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).
What are the official names of this protein?
Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note=Soluble, secreted forms seem to exist. They may arise by cleavage of the GPI anchor.
Protein: DTX9_ARATH
Sequence: MKKSIETPLLLNTKQSQDEDKEKIRWEKMKKVASMAAPMVAVNMSQYLLQATSTMIVGHRSELALAGIALGSSFANVTGFGVLFGLSGSLETLCGQAYGAKQYHKLGSYTFTSIVFLLIISVPISILWMFMNQILLLLHQDPQIAELAGVYCLWLVPALFGYSVLESLVRYFQSQSLIYPMVLSSLAALSFHVPLCWLMVHKFDFGAKGAAASIGISYWLNAVFLWVYMKRSSRCVETRIYMSKDVFVHTNIFFQFAIPSAMMCCLEWLAFEVITLLSGLLPNSKLETSVISICLTTSSLHYNLVNGIGDAASTNVANELGAGNPRGARDSAAAAIIIAAVESVIVSSSLFLSRSVWPYAYSNVEEVISYVTDITPILCISILMDSFLTVLSGIVRGTGWQKIGAYVNITSYYVIGIPVGLLLCFHLHFNGKGLWAGLVTGSTLQTLILFLVIGFTNWSKEAIKARERIGDEKVWRHDSLLN
What are the official names of this protein?
Protein DETOXIFICATION 9, AtDTX9, Multidrug and toxic compound extrusion protein 9, MATE protein 9.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TAL_BUCBP
Sequence: MNQLECLKKYTDIVVDSGDLVSINKFKLGDVTTNPSLIRQVMSLQKYQYIIYDSIRYAKKKGGSHKFKLENAIDKVSVILGSEILKNISGKISTEIDSRLSFNTNLCIERAKKLISMYEEHDIHRDRVLIKLAATWESVSAAKELKKENIQSNLTLLFSFAQAKICAEAGVFLISPFVGRIYDWYKSKSLIKSAMIDDDPGVNAVRKIYQYYKEYGYHTIIMGASFRNVDQVLALSGCDRLTISPNLLHKLQLSDDLVIRKLIPPKHKKLQPVCMSKSEFCWFHNEDAMAVEKLSEGIRQFGKDQQELENIINNNF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_PASMU
Sequence: MQNITIINTRCANLSSVKFAFDRLGYHTEITDNIEKIQSADKLILPGVGTAKAAMQNLADLGLIEVIQSLTQPVLGICLGMQLMTDYSEEGNLDLLKLMSGKTEKLPDCQLPLPHMGWNKVHYAADHPLFAEIAQDSYFYFVHSYGVLPNPHTVATCDYGVPFSAVIQHNNFYGAQFHPERSGKAGALFLRNFVENIK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_PSET1
Sequence: MSLSNQEKIDIIAKFARAEGDTGSPEVQVALLTFDINKLQGHFADHKHDFHSRRGLLRKVSQRRKLLDYLKGKDITRYTALIKELGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CHAD_BOVIN
Sequence: MARPMLLLXLSLGLLASLLPALAACPQNCHCHSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLATNSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRSGAFQGAKDLRWLYLSENSLSSLQPGALDDVENLAKFYLDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLHQLPSNFPFDSLETLTLTNNPWKCTCQLRGLRRWLEAKTSRPDATCASPAKFRGQHIRDTDAFRGCKFPTKRSKKAGRH
What is the function of this protein?
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts.  This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1).  May play an important role in the regulation of chondrocyte growth and proliferation.
What are the official names of this protein?
Chondroadherin, 38 kDa bone protein, Cartilage leucine-rich protein.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: EPHB6_PANTR
Sequence: MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAANPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQVEDESHSFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRRGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQACGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV
What is the function of this protein?
Kinase-defective receptor for members of the ephrin-B family.  Binds to ephrin-B1 and ephrin-B2.  Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2.  Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 6, Tyrosine-protein kinase-defective receptor EPH-6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: QUEC_META3
Sequence: MKAVCVLSGGLDSAVCMAMAKSEGLELYSITFDYGQRAVKKEIIASKKLSELFGAVHKVVELPFVKDFSSSALTKKEEEVPTIKNSELDNLEKATETMEKVWVPARNMILFSISSGFAEFVDAKYIYTGLNVEEGATFPDNTEEFLNRFNSVLEYGTLNKVKMKSPLYKYSKKEIVKIGKKLEEKLNVEFLKYSYSCYHDNKTDFLHCGTCESCMRRKRAFKEAGVEDPTEYIL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.