PharMolix/UniProtQA huggingface dataset:
Protein: RPB2_ASFM2
Sequence: MEPLRPQITYGPIEAVNNEELTEADMLSFISAAVNSTGLIGYNIKSFDDLMDNGIPQIVKQMFNVDITYKDQRDHTEIDKLRESVQIQFNFTDVNIERPQHRNYSQGNKINLLPNKARLCGLSYSGPVNLAAEVILTAHYSNGRQEVKRASIPPFQVSTFPIMRGSNRCHTYHLSKTAKKEIGEDPNEPGGYFIARGGEWVVDLLENIRFNTLHIHYHTMQQGNNEIIRGEFISQPGGAFENSSQIIIRYMTTGAITIEINSTKFSKLRIPWYLIFRMFGMTGDDSIIEQVVFDLESNSPVNTFMIEILEKSIHVSDPIFQPVQHELNREKIIQFLSEKVSKFVSNPSAYKSDENAVQYLNERQLTILDKILLPHMGQTADTRVRKLRFLGLLIHKILLVIMNVFPPTDRDSYRTKRVHGSGVSLAKAFKAIFNTSVIAPIINGFKELLKQTAFEDLTQRNIIEAFSAALSKNSASDLNRSMEQSIISGNKTIMVRQRPIVNRVSTQSLERKNLLNTISALRTVNTHSTTNASKQTERADMMRRVHASYPGYICVAQSADTGEKVGMSKQLAITANVCTAGEVLSLKQRLLSDPAIQQLADVSNKDIVRKGLARVFINGEWIGCCTNAFELAQRYRMLRREGKIVHPHTTIYWDSMVDEVEFWLDVGRLTRPLLIVDNNIEKYNKACYKAAEARKKGDKDWEKHKIPFIQNTRFTSQMAKDILAGTLTLEDLVAQGICEFITPEEAENCLVAFSITELRKHKHDVTRRFTHVDVPQAILGLAALVSPYANCTQPARVTYETNQGRQTGGWYCFSWPYRVDMNRFFQFYNEMPLVKTIAHNYVIPNGLNTIVAYMIYGGYNQEDSVIVSQSFIDRGGFAGTFYREEKVELESDIESFGKPDPLITKNLKPGANYEKLVDGFVPVGTVVKKGDIIIGKVAKIRGEKDELNKYIDRSVMYGFDEPAVVDAVMRPHGPNDEIFGLMRLRYERNLNIGDKMSSRSGNKGIAALALPTSDMPFTEDGLQPDLIVNPHSHPSRMTNGQMIETTVGLANALQGVVTDGTAFLPINVQLLSERLAQEGLRFNGCQKMFNGQTGEYFDAAIFIGPTYHQRLQKFVLDDRYAVASYGPTDALTGQPLDGKRSHGGLRLGEMEHWVLTAQGAMQTIIEKSHDDSDGCISYICRNCGEPAIYNASHPIYKCMNCDVQADISMVDSRRSSIVFQHEMRAANVNITSVLSPRVFQPA
What is the function of this protein?
Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).  Forms the polymerase active center together with RPB1 (By similarity).  Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase RPB2 homolog, RPB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: HIS4_XANOP
Sequence: MSFTVYPALDIRNGRVVRLLQGDYARETHYGNDVLPRAQAFADAGAQWMHLVDLDAAKAGGYTLATTLGEIARATGLQVQTGGGVRSRDDVASILDAGAARVVIGSLAVRDSEMVIAWLQEFGADRLTIALDTRQDTDGIWQLPVHGWTETADATLDQLAVRYAQAGLKHLLCTDIARDGMLSGPNAALYAHLRSLTPQLQVQVSGGARNLADVAAAKAAGCAGIVLGKALLEGHLDLDEALAC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP23_MAGO7
Sequence: MASPQDNTPSGATPKPQTHEETPDQVKLRINGGERLNIRKNNPAETGFDPATSKWVNYFKVLTGSMTKEGQFHYREHLYRTNEERDLRRCEEQRDWLFRYSPVVRYMRDQIRLLGGELDADNVVCRRCPSRLTADGRILGQAGGFSPQHGILVCANSIRDRKHLEDTLAHEMVHAYDHLRWQVDFVGEKDLRHAACTEIRASMLSGECRWTREAFGRGNWTVTQQFQNCVRSRAIMSVRARARCRDTEHATKVVNQVWDSCFSDTRPFDEIYK
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: COBT_CHLAD
Sequence: MSLLTQTINHIGPLDDQAATAARRRQDMLTKPAGSLGRLEELSIRIAGITGRERPRLTKPAVIVMAADHGVARQGVSAFPAEVTPQMVLNFLRGGAAINVLARHVGAQVIVVDIGVAADLPSHPELVSRKLAYGTADFSQEPAMSRDLAQQAIEVGITCANEAIDSGVDLLATGEMGIANTTAASAVVAAITGRPVAEVTGRGTGIDDASLARKIAVIERALVLHQPNPRDGLDVLAKVGGLEIGGLAGVILGAAARRVPVVIDGFISGAAALIAATLAPAAVNYMIAGHRSVERGHAAVFDRLDLKPLLDLDMRLGEGTGAVLAMSLCQAACKVLDEMATFAEAGVSEKKEA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: ASSY_THEVB
Sequence: MGRAEKVILAYSGGVDTSVCIPYLQHEWGVKEVITLAVDLGQGDELEPIRQKALDAGASASLVADAKAEFIRNYAFPAIQANALYENRYPLSTALARPLIAKLLVEAATQYGADAVAHGCTGKGNDQVRFDVAIAALNPNLKVLAPAREWGMSREETIAYGERFGIPAPVKKSSPYSIDRNLLGRSIEAGPLEDPWMEPLEEVYWMTQAIEHTPNSPEYVDIGFEAGVPVSLDGRPLDPVTLVSELNERVGRHGFGRIDMIENRLVGIKSREIYEAPGLLVLIDAHRDLESLTLTADVMHYKRGIEETYSRLVYNGLWYSPLKEALDAFIQQTQQRVTGTVRVKLFKGTARVVGRQSPYSLYTPDLATYGAEDQFDHRAAEGFIYVWGLPTRVWAEKLRQG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B_DROYA
Sequence: MPPKTSGKAAKKAGKAQKNITKTDKKKKRRRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FAD5C_DICDI
Sequence: MENEKKLFKKLYSWKEISKHNTIENGIWISIDGLVYDITKFIKHHPGGEQVLILAAGRDVTNLFESYHPMTDLPSKMLKQYEIGQVSTMEFPKYVEKSKFYSTLKERVREHFKKSNKDPKFAFGIIARLIFVYWFLITSYYVSHYAFIENFYLNCLLAIVYSLSNSLFSLHMMHDACHSAISHNPKVWKWLGATYDLFIGASFFYWCNQHVIGHHVYTNIRNADPDIGDSEVDFRIVTPYQNKYWIYKYQHIYAPFLYGLYSIKYRLCDYSVFTEGSIGRVRTANASNFEIISFIIGKLVFIVFRFIIPLQYHSLVNLLTYFFIAEFFFGLYLSFGFQVSHSADNLKIVATSVNENDEPTNVDEDWAIHQIKTTQDYGINSYMCLFFSGGVNLQVVHHLFPSISQEYYGELVPIIKKVCDEYDVHYNIQPTFYAAFKSHIDFLYNMGNNENYVRKSVTD
What are the official names of this protein?
Probable Delta(5) fatty acid desaturase C, Delta-5 fatty acid desaturase C.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPOT_ECOLI
Sequence: MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRVLGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENIQRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQEFITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLANIMRKIRVMPDVIKVTRNRN
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes both the synthesis and degradation of ppGpp.  The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it.  ppGpp activates transcription of CsrA-antagonistic small RNAs CsrB and CsrC, which down-regulate CsrA's action on translation during the stringent response (PubMed:21488981).
What are the official names of this protein?
Bifunctional (p)ppGpp synthase/hydrolase SpoT.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Is associated with pre-50S ribosomal subunits in a salt-dependent manner.
Protein: ACP_PSYIN
Sequence: MSNIEERVRNIIVEQLGVQLEEVKNEASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQSAIDYVVNNG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT1_STREI
Sequence: MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVEDTSAEEARLDAALKASQDELSIIREKAVETLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAEAGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGAKLPNPATIDEESIVIAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITSRVKDGDIVAVNGITGEVIINPTDEQVAEFKAAGEAYAKQKAEWALLKDAKTVTADGKHFELAANIGTPKDVEGVNANGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYLDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRIMFPMVALLKEFRAAKAIFDEEKANLKAEGVAVSDDIQVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWVGMCGEMAGDQKAVPLLVEMGLDEFSMSATSILRTRSLMKKLDTAKMQEYANRALTECSTMEEVLELSKEYVNVD
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_BACMK
Sequence: MSLGVIAAAIAIGLSALGAGIGNGLIVSRTIEGVARQPELKGALQTIMFIGVALVEALPIIGVVIAFIVMNK
What is the function of this protein?
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient.  F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2_JANMA
Sequence: MKKEDPNLSLFSFLDEDIICGVDEAGRGPLAGPVFAAAVILDPMRPIDGLRDSKKLTEVKRDALAIEIKQYALSWSIAQCSEEEIDSLNILQATMLAMRRAIEGLHVVPTLALIDGNRCPVTSVRSEAIIKGDDKVQAISAASILAKTARDHALGLLHIQYPHYAFDQHKGYPTALHLERLREHGVSPVHRKSYAPVRALLGGVTPANKV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C6A_RAT
Sequence: MSTKTVIRSQTSHRGFSAGSARLPGLNRSGFSSVSVCRSRGSGGSRAVCGGAGFGSRSLCGVGSSQRISIGGGSCGIGGGYGGRFGGSFGYGGGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINDLRKELDNILGQRGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEGVGPVNISVVQSTVSSSYGSAGGASSSIGLGGSSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGGSSSTIKYTTTSSTRKSYRP
What is the function of this protein?
Epidermis-specific type I keratin involved in wound healing.  Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration.  Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
What are the official names of this protein?
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Keratin-6A, K6A, Type-II keratin Kb6.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: Y4201_OPITP
Sequence: MRLTYFGHSAFLLELARTRLLFDPYLRENPHGSVDPKSVPCDLVFCSHAHSDHVGDALELARLHHAKIVAPYELAEHFAAQGAETIDLMPGGGVTLPWGRIDMTPAIHGSALELGDGKTLSMGPPSGFVVRADGQSLYHAGDTALFGDMRLIGRHGIDVALLPIGDFYTMGPADAVEALHLLRPRLAIPMHFNSNPKIRVDPHRFAAEARRTGHPVRVMSPGETIEV
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Oter_4201.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: TGT_VIBVY
Sequence: MKLKFDLKKKNGNARRGQLTFERGTVQTPAFMPVGTYGTVKGMTPEEVKETGAEILLGNTFHLWLRPGQEVMKMHGDLHDFMNWQGPILTDSGGFQVFSLGDIRKITEEGVHFRNPVNGDKIFMDAEKSMEIQKDLGSDIVMIFDECTPYPATHAEAKKSMEMSLRWAQRSRDHFDKLENPNNLFGIVQGGVYEDLRDVSVKGLTEIGFDGYAVGGLAVGEPKEDMHRVLEHTCPQLPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTGGVIKIRNATHKTDTTPLDPHCDCYTCKNYSKSYLHHLDRCNEILGARLNTIHNLRYYQRLMESIRKAIDEDRFEQFVEEFYARRNREVPPLGKQA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RUTA_ECO55
Sequence: MQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: BIOB_ESCF3
Sequence: MAHHPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLADAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CPY28_ARATH
Sequence: MASSSILIPPILTRRNLLLSTTIATVTPPPPAKPPSPDITITDRVFLDFSLCPTYFRSDPSATLSSTTPCSDSTPLGRVVLGLYGRHVPITVSTFKRMCTSSSTSYKNTPVHKIFPGQYFLAGRQGGGRRDTAEVGYSLRDLPRNTDVVNSKAFLLPHARAGVVSLCLSENDDDDDIRLDPDYRNVEFLITTGPGPSPQLDGGNIVFGTVLEGLDVVTSISSIPTYKPSENIKQFNDFAEFLGDERAQNARSLWNRPLKTVFISGCGELKVTNPSLSPTLP
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP28, chloroplastic, PPIase CYP28, Cyclophilin of 28 kDa, Cyclophilin-28.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSPO_ARCFU
Sequence: MNILKLVASILAVLAIGFAGSFFTAQSVQTWYAGVEKPFFTPPNWLFGPAWTLLYFLIGIVLYIAWENGFWNDSRVKATFFTQLGLNFLWSILFFGLQNPLAGLVDIIALDIAVILTIVYIYHHSKASLLLLPYLGWILFASALNFAIYLLNA
What is the function of this protein?
Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX (PubMed:23651039).  May play a role in the transmembrane transport of tetrapyrroles and similar compounds (By similarity).
What are the official names of this protein?
Tryptophan-rich protein TspO, Translocator protein TspO.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OM31_BRUSU
Sequence: MKSVILASIAAMFATSAMAADVVVSEPSAPTAAPVDTFSWTGGYIGINAGYAGGKFKHPFSSFDKEDNEQVSGSLDVTAGGFVGGVQAGYNWQLDNGVVLGAETDFQGSSVTGSISAGASGLEGKAETKVEWFGTVRARLGYTATERLMVYGTGGLAYGKVKSAFNLGDDASALHTWSDKTKAGWTLGAGAEYAINNNWTLKSEYLYTDLGKRNLVDVDNSFLESKVNFHTVRVGLNYKF
What is the function of this protein?
Major outer membrane protein associated with peptidoglycans.  May function as a porin.
What are the official names of this protein?
31 kDa outer-membrane immunogenic protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RLMN_MYCBT
Sequence: MVPELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLAHQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKTLWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAGAAALRDDFGDRLSNVVFMGMGEPLANYARVLAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLHAPDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQPWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAKGVSCTVRDTRGREISAACGQLAAVGG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAA10_BOVIN
Sequence: MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGSIENKMEGKGNSLPSSGEACREEKGLVAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
What is the function of this protein?
Catalytic subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase activity (By similarity).  Acetylates amino termini that are devoid of initiator methionine (By similarity).  The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development (By similarity).  Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (By similarity).  Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (By similarity).  Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (By similarity).  Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (By similarity).  Acetylates HIST1H4A.  Acts as a negative regulator of sister chromatid cohesion during mitosis (By similarity).
What are the official names of this protein?
N-alpha-acetyltransferase 10, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Also present in the free cytosolic and cytoskeleton-bound polysomes.
Protein: DEOC_PASMU
Sequence: MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKICTVVGFPLGANLSTVKAFETTEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACAGKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFNRGGATKEDVALMKRTVGDIGVKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_PICAN
Sequence: STPVDPKTKANALIDSLPGNSFLSKTGILATTAAASVYAISSELYVVNDESILLVTFLGFIALISKTVAPLYGEMAKNRTDHVVGLLNQARADHVNAVKTRIDQVSNLKDVVSTTKALFEMSKETAALEAEAFELKQKVAVASEAKSVLDSWVRYEAQVRQHEQEQLASTVISKVQSELQNAKFQDKVLAQAVEEVERLFAKEK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (PubMed:27791192).
What are the official names of this protein?
ATP synthase subunit 4, mitochondrial, ATP synthase subunit b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.