PharMolix/UniProtQA huggingface dataset:
Protein: MCA1_YEAST
Sequence: MYPGSGRYTYNNAGGNNGYQRPMAPPPNQQYGQQYGQQYEQQYGQQYGQQNDQQFSQQYAPPPGPPPMAYNRPVYPPPQFQQEQAKAQLSNGYNNPNVNASNMYGPPQNMSLPPPQTQTIQGTDQPYQYSQCTGRRKALIIGINYIGSKNQLRGCINDAHNIFNFLTNGYGYSSDDIVILTDDQNDLVRVPTRANMIRAMQWLVKDAQPNDSLFLHYSGHGGQTEDLDGDEEDGMDDVIYPVDFETQGPIIDDEMHDIMVKPLQQGVRLTALFDSCHSGTVLDLPYTYSTKGIIKEPNIWKDVGQDGLQAAISYATGNRAALIGSLGSIFKTVKGGMGNNVDRERVRQIKFSAADVVMLSGSKDNQTSADAVEDGQNTGAMSHAFIKVMTLQPQQSYLSLLQNMRKELAGKYSQKPQLSSSHPIDVNLQFIM
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues (PubMed:22761449).  Mediates cell death (apoptosis) triggered by oxygen stress, salt stress or chronological aging.  Regulated cell death can prevent a release of toxic cellular components, thus avoiding necrotic collapse of the colony, and can also provide nutrients for healthy cells.  Therefore, regulated cell death in yeast colonies can be as important for their development as are apoptosis and related processes that occur within metazoa.  Promotes the removal of insoluble protein aggregates during normal growth.
What are the official names of this protein?
Metacaspase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VATB_ENCCU
Sequence: MLESVRIEPKMSYRKIVGVNGPLVIMDNIRFLKYAEMVSLTLPDGSVRQGQVLEVSGKKAVIQVFEGTAGIDVKETQVTFTGETMKMGMSEDVLGRIFNGSGRVIDGGPKIIPEDYLDIQGQPLNPYARIYPEEMIQTGISSIDVMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVKRKDSIDSSDDNFAIVFAAMGVNVETANFFRNSFEASGSIGRTALFLNLANDPTIERIITPRLALTAAEYLAYEREKHVLVIMTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRLEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQMHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAQAMKAVVGEDSLSAEDRISIEFLERFEREFISQRHDELRTVDQSLDIAWDLLKVFPREMLNRIPSDILDEFHSVAPVGVE
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit B, V-ATPase subunit B, Vacuolar proton pump subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: INS_LOPPI
Sequence: VAPAQHLCGSHLVDALYLVCGDRGFFYNPKGIVEQCCHRPCNIFDLQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BTUF_SALTI
Sequence: MAKQMFRALGALLLTLPVWLYAAPRVITLSPANTELAFAAEITPVGVSSYSDYPPEAQKIEQVSTWQGMNLERIVALKPDLVVAWRGGNAERQVNQLTSLGIKVMWVDAVTIEQIADALRQLAAWSPQPEKAQQAAQTLLKEYAALKVEYAGKAKKRVFLQFGMNPLFTSGKGSIQHQVLTTCGGENVFADSRVPWPQVSREQVLARHPQAIIVAGKAGEILKIEQYWGNLLKIPVIPLNSDWFERASPRIILAAKQLCNALSQVN
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DF114_ARATH
Sequence: MAITKKCFAAFVLILLFVMPFVYCSELDNTSGFEIKQEDKCYGPEPCKNGYEGCLFFCVRIAYYLYGECTMKPDHQKHCCCVTK
What are the official names of this protein?
Putative defensin-like protein 114.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY1_RHIL3
Sequence: MLSNLMSWQITLPIALAAAIIGYLFGSIPFGLILTRAAGLGDVRSIGSGNIGATNVLRTGNRTLAAATLLLDALKASAAAWVVSYFLGEEAAIIAGFFAFIGHLFPVWIGFKGGKGVATYIGTLLGVAPIMVVLFAAVWLAVAFTTRYSSLSALVAMLVIPVALWILGNEKVAAVMAIMTLISYWKHKANISRLMGGTESKIGAKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 1, Acyl-PO4 G3P acyltransferase 1, Acyl-phosphate--glycerol-3-phosphate acyltransferase 1, G3P acyltransferase 1, GPAT 1, Lysophosphatidic acid synthase 1, LPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABPM_SCHGR
Sequence: MVKEFAGIKYKLDSQTNFEEYMKAIGVGAIERKAGLALSPVIELEILDGDKFKLTSKTAIKNTEFTFKLGEEFDEETLDGRKVKSTITQDGPNKLVHEQKGDHPTIIIREFSKEQCVITIKLGDLVATRIYKAQ
What is the function of this protein?
Binds fatty acids in a 1:1 molar ratio.
What are the official names of this protein?
Fatty acid-binding protein, muscle, M-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_THAPS
Sequence: MINIRPDEISSIIREQIEQYDQDVKIDNIGTVLQVGDGIARVYGLDQVMSGELLEFEDKTIGIALNLENDNVGVVLMGNGRQILEGGSVKSTGQIAQIPVGEAFLGRVVNPLGAPIDGKGDIASTETRLVESMAPGIISRKSVCEPLQTGITSIDAMIPIGRGQRELIIGDRQTGKTSIAVDTIINQKTEDVVCVYVGIGQKASTIAQVVNVLDEKEAMAYTIIVSASANDPATLQYIAPYSGAALAEYFMYNGKATLIVYDDLTKQAMAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDALGGGSMTALPIIETQASDVSAYIPTNVISITDGQIFLSNDLFNSGIRPAINVGISVSRVGSAAQTKAMKQVAGKLKLELAQFAELEAFSQFASDLDEATQKQLARGTRLREILKQPQNSPLSVAQQVALIYAGINGFLDNLAVSDVKKFSASLIQTLASQKSYIDVVGKTNQFTEEAETLLKEAIASTKTGFATL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CCSA_GALSU
Sequence: MLTLNMNLNYQIDNYCLNISFLSLFISMICYWLVIAFPKKIFFLKFAHFEVSLANILLVYLLAYRWLKYSYFPLSNLYESLLFLSWSLTTIQLILEFKFKHKLIGAIASPISTLTLAFSSFFLPKYMQEVSPLIPALKSNWLLMHVSVILISYAMLLIGSLLSILFLLLSRNNKLNYTKNNNLTTASNSNDTLILKNEDKLNLLNTIDNLSYRIIGLGFPFLTIGIISGAVWANEAWGSYWSWDPKETWALITWIIFAIYLHTRINKSWQGKKSAIVAGFGFVVVWICYLGVNFLGKGLHSYGWFL
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FTSH_LACP7
Sequence: MKKLYWIILIAVVLACSGILMSLHLSVTKEEMTYPSFLDAVNQNQVASVQFKENDSTLKVILNSDKDTTYIVPNPKTENFTEFLLLRNIKVDNSDSYSATKVIQIILIITVGTGVFLFIRTSGGKDKPLMKDAAKNKKAENRVKLGDVAGNAEAKSMVGDIIDFIKEPEKYSALGARMPKGVMLYGPPGTGKTLIAKAIATEAGVPFYAMSGSDFVQMYVGVGASRIRTLFNKAKKSEKAVIFIDEIDAIGKKRARSTSASNDERDQTLNALLTEMSGFHENKGIVVIGATNRLDTLDEALLRPGRFDRQIEVGLPDILARKKILKLYGDKKPLGDDVDLEVLAKNTVSFSGAMLENLLNEAAIQAANEKSSYIQSSHVDKAFYTVIAGSPLQDRSFISEKDKSITAYHEAGHALATKLLQPEQYISKVTIIPSVKGAGGFNLSIPKDSLYQSKRQILCSIQILLAGRVAEELIFGEEEITTGASNDIQKASAMLVDYLNKYGMDDEMGLFSTVVLEDQYDTDFLNKCRNQMHALYDTTKKLMTENKKLLIEITNELLEKESLKGEDIDRICLKEAV
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RL36A_CAEEL
Sequence: MVNVPKARRTFCDGKCRKHTNHKVTQYKKGKESKFAQGRRRYDRKQSGFGGQTKPIFRKKAKTTKKIVLRMECTECKHKKQLPIKRCKHFELGGQKKSRGQVIQF
What are the official names of this protein?
Ribosomal protein rpl-36.A, 60S ribosomal protein L44, L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: ACDE2_ARCFU
Sequence: MAKALEQPFDVANIPGPKMATLLEKGKPVANMIKKAKRPLLIVGPDMTDEMFERVKKFVEKDITVVATGSAITRFIDAGLGEKVNYAVLHELTQFLLDPDWKGFDGQGNYDLVLMLGSIYYHGSQMLAAIKNFAPHIRALAIDRYYHPNADMSFGNLWKKEEDYLKLLDEILAEL
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.  The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit epsilon 2, ACDS complex subunit epsilon 2, ACDS complex carbon monoxide dehydrogenase subunit epsilon 2, ACDS CODH subunit epsilon 2.
What is the protein family that this protein belongs to?
Belongs to the CdhB family.
Protein: RF1_AQUAE
Sequence: MLKEAYISRLDKLQEKYRKLQEELSKPEVIQDVEKYKKLSKELKELQEINELYERYKKAQKELKEAKELLKSSDKDLRELAEEEVNRLTEEMKKLEEELKVHLVPKDPNDTKNVILEIRAGAGGEEAALFAADLFRMYQKYAEEKGWKVSILSSNKTGLGGYKEVIALIEGEGAYSRLKYESGVHRVQRVPVTESSGRIHTSTATVAVLPEVDETDIKIKPEELKIETFRASGAGGQYVNTTETAVRITHIPTGIVVQCQDERSQFQNKQKALKILYAKLKDYYERKKQEEIAKERKEQVGTGERSEKIRTYNFPQNRVTDHRINLTLYKLQDVLEGKLDEIIDALRAKEIEKKLELVEKEG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_CAEEL
Sequence: MMFLFVSLFMFIFKWQRLIFILISLEFMMLSLFLKFSYVLGEMMFFYFMCFSVISSILGMVVMVGNMKFFGSDNCIF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ECOT_ECO57
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDTGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DPO4_SHEON
Sequence: MRKIIHVDMDCYFAAVEMRDFPEYRGKPLAVGGSRERRGVISTCNYEARRFGVRSAMATAYAQKLCPDLILVPGRMQVYKDVSSQIRAIFSRYTELIEPLSLDEAYLDVSDCKLHKGSATLIAEAIRRDILAETGLTASAGVAPVKFLAKVASDLNKPNGQYVIPPDKVPEFIRTLSLRQIPGVGKVTAEKLSSLGLNTCGDVQTYPKQELITRFGKFGAVLIERAQGIDDRGLSVSRERKSVGVETTLAQDIYTLEQCQQVMPGLIQELSTRLSRSAKDRQIHKQVVKLKFSDFKQTTIEHRSNDVSVMMFYELLAQAIARQDGRGIRLLGVAVGLSDKSLISEVDPLQTQLVLSI
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CLOBB
Sequence: MEFKHISVLLNECLDALDIKDNGIYVDCTLGGAGHSSHILERLSNEGLLIGIDQDRDALKAAKERLKRFENVKYVHSNFYDIDNILQNLDIPKVDGILMDLGVSSYQLDEGARGFSYMKDAPLDMRMNRDNDFSAYEIVNEYSEDELYKIIRNYGEERFAKRISNCIVNRRSDKPIETTMELVDIIKAAIPAKARREGPHPAKRTFQAIRIEVNSELKILNQTIEDGVNRLKPGGRMAIITFHSLEDRIVKLKFRELNDPCTCPREFPMCICGKKPSVRLISRKGIEPTKEEVEENPRSRSAKLRIIEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_SHESA
Sequence: MKYRLIVALAMLVLSLPSQAERIKDIANVQGVRSNQLIGYGLVVGLPGTGEKTNYTEQTFTTMLKNFGINLPDNFRPKIKNVAVVAVHADMPAFIKPGQQLDVTVSSLGEAKSLRGGTLLQTFLKGVDGNVYAIAQGSLVVSGFSAEGLDGSKVIQNTPTVGRIPNGAIVERSVATPFSSGDYLTFNLRRADFSTAQRMADAINDLLGPDMARPLDATSVQVSAPRDVSQRVSFLATLENLDVIPAEESAKVIVNSRTGTIVVGQHVKLLPAAVTHGGLTVTIAEATQVSQPNALANGETVVTANTTIGVNESDRRMFMFSPGTTLDELVRAVNLVGAAPSDVLAILEALKVAGALHGELIII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CM34_CONLT
Sequence: MLKMGVLLFTFLVLFPLAMFQLDADQPVERYAENKQDLNRDERMKIMLSALRQRQCCDWEWCDELCSCCW
What are the official names of this protein?
Conotoxin Lt3.4, Lt3d.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TARI_STRR6
Sequence: MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPLTPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMIEKD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: TBL9_ARATH
Sequence: MDHHQLFSLCSFSYIFKIKKHLFVSLFLLSLLIFSTVVVDVMPSLRIGLLSSSSSQTVTKECDYSKGKWVRRASSSSSSVNGLFYGEECRFLDSGFRCHKHGRKDSGYLDWRWQPHGCDLPRFNASDLLERSRNGRIVFVGDSIGRNQWESLMCMLSQAIPNKSEIYEVNGNPITKHKGFLSMRFPRENLTVEYHRSPFLVVIGRPPDKSPKEIKTTVRVDEFNWQSKRWVGSDVLVFNSGHWWNEDKTVLTGCYFEEGRKVNKTMGVMEAFGKSLKTWKSWVLEKLDPDKSYVFFRSYSPVHYRNGTWNTGGLCDAEIEPETDKRKLEPDASHNEYIYKVIEEMRYRHSKVKFLNITYLTEFRKDGHISRYREQGTSVDVPQDCSHWCLPGVPDTWNEILYAQLLSMNYRTK
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 9.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: ECFT_LACH4
Sequence: MMGLRKMCRGSLMSKIIIGRYIPGDSLVYKMDPRGKLLITILFIWAIFLANNPITYAIITFFCFLAIIATGLKARVFWNGVKPLIGLIFFTSLLQLFFMTGGHVFWHWWIFSISSYGVENAIYIFIRFTLIILISTVMTVTTMPLEIADAMEWLLKPLKIFKVPVDEIALVISIALRFVPTLFDETLKIMNAQRSRGADFNDGGLIKRAKAIAPILVPLFIHSLETAIDLSTAMESRGYRGSAGRTKYRVLNWSKYDLISLAYFILLVGLLLIFRTH
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOLB_WIGBR
Sequence: MKRLLFFLICVFFSKTSYSNVDISINKGIDISTPIGISSFEWVEVNENNNYENISKIISCDLQNSGKFSPIEIYKESNKSIEKQIKNNSINLNKLNINTILTGKISLNYNGEYLISYKLIDLVNYPGKILLSGYRTVHLQSFRKVAHEISNEIFKKLTGIQGVFHTRIAYILYNKNNEYKYKLCISDYDGYNQNIIHQSNMPLMSPSWSPDGKKIAYVTFEKGSSEIKIKDIKTGSIKHISSFPYHNGAPAFSPNGENLAFALSKTGSLNLYVMNLKNGYIKQITHGNSNNTEPSWFPDNNSLAYTSDQSGTPQIYKINISNGKFNRLSWLGSKNQNANVSPDGKFIAMVNSEKKSQHIALFDINMDNAKIITETFLDEAPSISPNNVMIIYTSSYGDSSVIELISTNGRFKTSILKINGQIKFPAWSQKI
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TIG_MYCGI
Sequence: MKSTVEKLSPTRVRINVEVPFAELEPDIDKAFKQLAQQIRLPGFRPGKAPRKLLEARVGRGAVLEQVVNDALPTRYSQAVTSESLQPIGQPEIEVTKLEDNEELVFTAEVDVRPEIDLPDLSTLTITVDPVSVTDEDIEAEIEALQKRFGTLTGVERPAENGDFVSIDLSATVDGKDVPEAKTEGLSHELGSGQLIEGLDEAIIGLSEDESKTFTTTLVAGEHAGREAEVTVTVKSIKVRELPELDDEFAQLASEFDTMDELRADLREKVTRVKTVQQAEAIRDKAIEVLLEQTEVPLPEAVVQAQVDDTLHNAIHGLDHDEDRFADSLKEQGSSREEFDADNRANAEKAIKTQLLMDAIADKLEIQVGQNDLSERLVLMSRQYGLEPQQLLQMLQQNNQLPAMFADVRRGLTVAAVVYAATVTDTDGTEIDTTEFFGPSGDQAAAQQGAGEDDSEAAVEVSEDTADDASEDDTADDTK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL33_PORG3
Sequence: MAKKVKGNRVQVILECTEHKESGMPGISRYITTKNRKNTTQRLELKKYNPILRRMTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RNH2_CLOTE
Sequence: MEKEIYKMDFNDMTFKDIKDIVDGMKKVENIECLIYINDILMKDKRKTVQNLSQSINKFICRREEEIVRLKKMYDFDKKFANNVLIAGVDEVGRGPLAGPIVAAAVILDLNYKNHNDLFYGLKDSKKLRAKERENLSHIIKDKALYYNIFELDNHMIDTSGIAWCNNEVLKKSTLGLEVTPGIVISDGFSIKNINIKNEYIIKGDAKSASIAAASIIAKVYRDKKMEEYSKIYPHYGFEKNSGYGTDEHTKALKKYGPCPIHRMSFLSNYI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_THESQ
Sequence: MKSFDEMTPKEIVQELDKYIVGQYEAKKAVAIAVRNRIRRQKLPEEWRKEVLPKNILMIGPTGVGKTEIARRLAQLSGSPFLKVEATRFTEVGYVGKNVDSMIRDLVEISVNMVKQEKIKEVERQAEELVEERILDALVPESKAVPVVTNPFINLITGGQQQQYTPEDRRRFRAKREEMREKLRKGELENEEIEIELEETVSPFMGIFGPGMEDLGIEITNMFSGMLPKQKKKRKMKVSEARKVLLPLEAEKLIDMDKVVQEALDRAQNRGIIFIDEIDKIAGKESAVGPDVSRQGVQRDLLPIVEGTTIMTKYGPVRTDYILFIAAGAFHVSRPSDLIPELQGRFPIRVELSPLTEEDFVRILKEPENAIIKQYQALLSTEGVELVFTEDGIREMARIAYQLNQRLENIGARRLYTVAEKVLEEISFEAPDIPEKRIVVDAEYVRRRLERIVQDEDLSAYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYCO_RABVR
Sequence: MVPQVLLFVLLLGFSLCFGKFPIYTIPDELGPWSPIDIHHLSCPNNLVVEDEGCTNLSEFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVRTTKESLIIISPSVTDLDPYDKSLHSRVFPGRKCSGITVSSTYCSTNHDYTIWMPENPRPRTPCDIFTNSRGKRASNGNKTCGFVDERGLYKSLKGACRLKLCGVLGLRLMDGTWVAMQTSGETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLKVGGRCHPHVNGVFFNGLILGPDDHVLIPEMQSSLLQQHMELLESSVIPLMHPLADPSTVFKEGDEAEDFVEVHLPDVYKQISGVDLGLPNWGKYVLMTAGAMIGLVLIFSLMTWCRRANRPESKQRSFGGTGGNVSVTSQSGKVIPSWESYKSGGEIRL
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.