PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_GEOSL
Sequence: MKNLNLYHFFDCKDRKITMYRLTEKGERIRDMFSDIAPRYDFLNRLLSFGVDRRWRRNAVKCIRWSEGGRVLDVATGTGDVALEIARQTPPSVAIVGVDFSEGMVALGRDKVAGSPYAGRITMEIAPCEAIPFPDDTFDSVTIAFGIRNVVDRSQGLSEMLRVLKPGGRAVILEFSTPRSRLFKRIYSFYFLRVLPVIGGLFSQFGAYKYLPDSVLEFPSQEEFKALMASVGFRDTAHRDQTFGIATIYTGEKGLK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PTH_HAEI8
Sequence: MSEIKLIVGLGNPGEKYADTRHNAGEWLIERLARRFNVSLNPESKFFGKTARTLVNGKEVRLLVPTTFMNLSGKAVGALASFYRIKPEEILVIHDELDLPAGTAKLKQGGGHGGHNGLKDIVAQLGNNNNFYRLRIGIGHPGHRDLVAGYVLNKPSPADRDALEKVLDEATDCVEIIFKDGMIKATNRLNSFKI
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR2M5_HUMAN
Sequence: MAWENQTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYFLLSQLFLMDLMLICSTVPKMAFNYLSGSKSISMAGCATQIFFYVSLLGSECFLLAVMSYDRYIAICHPLRYTNLMRPKICGLMTAFSWILGSMDAIIDAVATFSFSYCGSREIAHFFCDFPSLLILSCNDTSIFEKVLFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLMVVGMYYGAGLFMYIRPTSDRSPMQDKLVSVFYTILTPMLNPLIYSLRNKEVTRALRKVLGKGKCGE
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2M5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACTHR_PIG
Sequence: MKHITDLYESVNSTMSNKSDCPPVVLPEEVFFTISVIGVLENLIVLLAVIKNKNLQSPMYFFICSLAISDMLGSLYKILENILIIFRNMGYLEPRGGFESTADDVVDSLFILSLLGSICSLSAIAADRYITIFHALQYQRLVTPRRAAVVLLIIWACCIGSGITIVTFSHHVPAVIAFTALFPLMLVFILCLYGHMFLLARSHARRVSTLPRANMKGAITLTVLLGVFIFCWAPFVLHILLMTFCPADPYCACYLALFQVNAVLIMCNAIIDPFIYAFRSPELRDAFKKMIICKRYP
What is the function of this protein?
Receptor for corticotropin (ACTH).  This receptor is mediated by G proteins which activate adenylate cyclase (cAMP).
What are the official names of this protein?
Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSC1L_BRAJU
Sequence: MEFASFLVSLGTSAIIFVVLMFLFTWLSRRPGNVPVYYPNRILKGMDPWEGSSLTRNPFAWIREAFTSTEQDVVKLSGVDTAVYFVFQSTVLGIFALSALLLLPTLLPIAATDNNLETSRSATDTTSNGTFSQLDNLSMANITKSSSRLWAFLGAVYWVSVVTYFMLWKAYKHVAALRAQALMTSEEVLPEQFAILVRDIPSPPNGETQKEFVDSYFRDIYPETFYRSLVVTENSKINKIWEDLEGYKKKLARAEAAFAATSNRPTNKTGLLGLVGERVDSIDYYTKLINESVAKLEAEQRTVLAERQQTAAVVFFTDRVTAALAAQSLHCQMVDKWTVTEAPEPRQLIWENLKIKFFSRIVRQYVIYFLVAITILFYMIPIAFVSAITTLANLQKALPFLKPIVDIAFIRTILESYLPQIALIVFLAMLPKFLMFLSKSEGIPSQSHAIRATSGKYFYFSVLNVFIGVTLAGSLFENLKALEEKPNSFITLLATSLPKSATFFLTYVALKFFVGYGLELSRIIPLIIFHLKKKYLCKTEAEVKEAWYPGDLSYATRVPSDMLILTITFCYSVIAPLILVFGVIYFGLGWLILRNQALKVYVPSYESYGRMWPHIHTRILAALFLFQLVMFGYLGVKIFVWAILLVPLIFISLIFGYVCRQKFYGGFEHTALEVACRELKQRPDLEEVFRAYIPHSLSTHKGDDHQFKGAMSRYQDYAAISAA
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
CSC1-like protein ERD4, Protein EARLY-RESPONSIVE TO DEHYDRATION STRESS 4.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: SMD3_MOUSE
Sequence: MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:19470752).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: TRPB_SALG2
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TRPD_PASMU
Sequence: MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVTALQADAESFPIPDYPFADIVGTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTGASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGFQHAIPVRQALKTRTIFNILGPLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKAGQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMSLFGYPNLKQNAQAIMDIIATGKPFETLQQLTQY
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: VM3A2_DEIAC
Sequence: KREAEANRTPEQQIYDPYKYVETVFVVDKAMVTKYNGDLDKIKTRMYEAANNMNEMYRYMFFRVVMVGLIIWTEEDKITVKPDVDYTLNAFAEWRKTYLLAEKKHDNAQLITGIDFRGSIIGYAYIGSMCHPKRSVGIIQDYSPINLVLAVIMAHEMGHNLGIHHDDGYCYCGGYPCIMGPSISPEPSKFFSNCSYIQCWDFIMNHNPECIDNEPLGTDIISPPLCGNELLEA
What is the function of this protein?
Snake venom zinc metalloprotease that acts at several levels.  It has direct fibrino(geno)lytic activity (Aalpha chain of fibrinogen is cleaved quickly, Bbeta chain slowly, and gamma chain even more slowly) and degradation of TNF-alpha.  These activities permit to protect against sepsis and disseminated intravascular coagulation (PubMed:18634754, PubMed:17964518, PubMed:19013210, PubMed:19070354).  It inhibits ADP-induced platelet aggregation in human platelet-rich plasma (IC(50)=65. 4 ug/ml) (PubMed:19013210).  It decreases the activity of complement by degrading human C5, C6 and C9 in vitro, decreasing serum levels of C1q, C3 and C4 in rat, and inhibiting the MAC deposition on HUVECs membrane.  This inhibition of complement protects against hyperacute rejection that is the main barrier in xenotransplantation (PubMed:23178656).  Has preference for Lys at the P1 position.  Cleaves insulin B chain at '36-Val-|-Glu-37', '39-Leu-|-Tyr-40', and '48-Phe-|-Phe-49' bonds.  Also cleaves fibronectin and type IV collagen (PubMed:19013210).
What are the official names of this protein?
Zinc metalloproteinase recombinant fibrinogenase II, FIIa, rF II, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SELD_METSB
Sequence: MLDAPVRLTDLAHGGGCGCKLAPSVLQQLLANQPQAAPYAQLLVGTETGDDAAVWQIDEERCVIATTDFFMPMVDDPRDFGRIAAANALSDIYAMGGTPIMALAILGMPLGKLPIETVRAILAGGASICAEASIPVAGGHSIDSPEPIYGLAVVGLCAVSDIRRNSGARPGDALILTKGIGVGVYSAAFKKQALSNAAYEEMMASTTLLNRVGHKLAKDDDVHAMTDVTGFGLLGHGVELARGGGVALDIDFARIPFLKEAQELAEAGLITGASGRNWASYGDAVVLPAETPDWRRALLTDPQTSGGLLIACAPERAEAIRGTIEAAGFPRATIIGAVAAGEPAVRIG
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: DGTL1_MYCSJ
Sequence: MNPRLQDSYDEFDRQRRVDEPAKSAVLPGTGTEHRTDFARDRARVLHCAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAVGLGCDPDLVDLAGLAHDIGHPPYGHNGERALNEIAKAFGGFEGNAQNFRILTRLEPKVLDATGRSAGLNLTRAALDAVTKYPWQRGDRTKFGFYGDDMAAARWVRDGAPAERPCLEAQVMDWADDVAYSVHDVEDGVVSGRIDLRVLADDDAAASLARLGAEAFPTLAPDDLLAAAERLSQMPVVSQVGKYDGTLGASVALKRMTSELVGRFANAAITETRSVAGGGALHRFDTELAVPTLVRAEVAVLKMLALQFIMSDHGHLGIQADQRTRIHEVALILWGQAPSSLDPLFAPEFVAAEDDGARLRVVIDQIASYTEGRLERVHEARSPRPLD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: GATB_STRPD
Sequence: MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGAIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVSLGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PP270_ARATH
Sequence: MYLKEGCSLLLKVQKPLIPFVLNTNLNVNHLLTESPNHAEIKELDVVKRLRQESCVPLALHFFKSIANSNLFKHTPLTFEVMIRKLAMDGQVDSVQYLLQQMKLQGFHCSEDLFISVISVYRQVGLAERAVEMFYRIKEFGCDPSVKIYNHVLDTLLGENRIQMIYMVYRDMKRDGFEPNVFTYNVLLKALCKNNKVDGAKKLLVEMSNKGCCPDAVSYTTVISSMCEVGLVKEGRELAERFEPVVSVYNALINGLCKEHDYKGAFELMREMVEKGISPNVISYSTLINVLCNSGQIELAFSFLTQMLKRGCHPNIYTLSSLVKGCFLRGTTFDALDLWNQMIRGFGLQPNVVAYNTLVQGFCSHGNIVKAVSVFSHMEEIGCSPNIRTYGSLINGFAKRGSLDGAVYIWNKMLTSGCCPNVVVYTNMVEALCRHSKFKEAESLIEIMSKENCAPSVPTFNAFIKGLCDAGRLDWAEKVFRQMEQQHRCPPNIVTYNELLDGLAKANRIEEAYGLTREIFMRGVEWSSSTYNTLLHGSCNAGLPGIALQLVGKMMVDGKSPDEITMNMIILAYCKQGKAERAAQMLDLVSCGRRKWRPDVISYTNVIWGLCRSNCREDGVILLERMISAGIVPSIATWSVLINCFILDDIVRAHDQFTI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g48810.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: ARGC_NEIMA
Sequence: MSKKIKVGIVGATGYTGVELLRLLAAHPDVEVAAVTSRSEAGTAVADYFPSLRGVYGLAFQTPDEAGLEQCDIVFFATPNGIAMKDAPRLIEQGVRVIDLSADFRIRDIPTWEHWYGMTHAAPDLVSQAVYGLSELNREAVAQARLVANPGCYPTCVSLPLVPLLRQCRLKPGMPLIADCKSGVSGAGRKGNVGSLLCEVGDNFKAYGIAGHRHLPEIRQTIAGLQDGIAEGFVFTPHLAPMIRGMHATVYLHLSDGICPETILRDYYRDSLFVDILPAGSTPETRSVRGANLCRISIQQAAQSDVWVVLSVIDNLVKGAAGQAVQNMNIMFGLKETHGLGAIPLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAG_YERPA
Sequence: MSAPHSALQAELDAAQSPYLAFRGIGKSFPGVLALDDISFTCQAGQIHALMGENGAGKSTLLKILSGNYTPTQGEIHIKGKAVNFTNTTDALDAGVAIIYQELHLVPEMTVAENIYLGQLPTKMGMVDRKLLRYESRIQLSHLGLDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALSDAITVFKDGRYVRTFDDMTQVNNASLVQAMVGRNLGDIYGYQPREIGSERLTLQAVKAIGVASPISLTVHQGEIVGLFGLVGAGRSELLKGLFGDTKLTSGKLLLDGQPLTIRSPIDAISAGIMLCPEDRKADGIIPVHSVQDNINISARRKTLTAGCLINNRWEADNALLRIQSLNIKTPGPQQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYQLAKQGIAVLFASSDLPEVLGLADRIVVMREGAISGELDHEYATEEQALSLAMLRTPNIATNTASAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROB_METCA
Sequence: MQSRNELPGSRRVIVKIGSALLTAGGKGLDQPAIGQWVQQIAELRQQGIQVVLVSSGSVAEGMSRLGWKTRPHRLNELQAAASVGQMGLVQTYESLFKRHGLQTAQILLTHDDLSNRERYLNSRSTILTLLELGVIPVINENDTVTTEEIRFGDNDTLGALVANAVEADLLIILTDQAGLFERNPSLDPSAPLVPQAGINDPRLNDMVGDSLSGLGRGGMITKLRAARLAARSGTATVIASGRESGVLPRILDGEELGTLLIPDVSPLIARKRWMAGQLKLKGCFVVDEGAARVLRDAGKSLLPIGVIAVEGEFRRGDLVACTDSAGQEIARGLTNYSAEEARLIMRQPSTRIEEILGYVDEPELIHRDNLVLS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERG8_ASPFU
Sequence: MLPLPPAVTALSAPGKVLLTGGYLVLDRSYTGTVFALDARIHVIVQQLRRNHRREAASGSAHGRSDTPQAEGNVHGDKEDEGTIVVHSPQFVDAVWEYSIQRCEDGGGVLVKQRNDGPRNLFVETSLNFALTYISYVADSKDFGSLSITILADNDYYSETAFSKASGLRSSSRFVDFGVRLQEAHKTGLGSSAALVTALVSSLVIHRTMQPDDLGPGRDKLHNLAQAAHCAAQGKVGSGFDVAAAIYGSCLYRRFSPSILESVGDAGSPGFEERLFRIVEDADPQHPWDTECLDFGMKLPRGMQMVLCDVECGSQTPSMVRKVLEWRKQNQKEADMLWGALQSNNERLRLELRRLAQSPDEHTLSDFENVRTYIQRSRNHIRSMTQKSDVPIEPRVQTELLDALSELEGVIGGVVPGAGGYDAIVLLIQDNPDVITRLKAFFETWESKAEDDFGGKIGKVRLLGVRHGSEGVKNEMLEQYAGWV
What is the function of this protein?
Phosphomevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  Erg8 converts 5-phosphomevalonate to 5-diphosphomevalonate (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 (AFUA_4G07780) first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8 (AFUA_5G10680).  The diphosphomevalonate decarboxylase mvd1 (AFUA_4G07130) then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 (AFUA_6G11160) then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase erg20 (AFUA_5G02450) catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:16110826, PubMed:22106303) (Probable).
What are the official names of this protein?
Phosphomevalonate kinase erg8, Ergosterol biosynthesis protein 8.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
Protein: ILVD_MYCPA
Sequence: MPTTDSARAADIKQPDIKPRSRDVTDGLEKAAARGMLRAVGMGDEDFAKPQIGVASSWNEITPCNLSLDRLAKAVKEGVFAAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLASVFLYAGSILPGVAKLSDGSEREVTIIDAFEAVGACARGLMPREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAIAHEADVALSLDDFSRIGSKVPHLADVKPFGRHVMTDVDHIGGVPVMMKALLDAGLLNGDCLTVTGATVAQNLAAIAPPDPDGKVLRALSDPLHPTGGITILRGSLAPEGAVVKSAGFDSDVFEGTARVFDGERAALDALEDGTITKGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVDAGPIAFLRDGDRIRLDVANRVLDVLVDPAEFDSRRTGFTPPPPRYKTGVLAKYVKLVGSAAIGAVCG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: BETB_BRUO2
Sequence: MKAQPKASHFIGGAFVEDKAGKPLPVIYPATGEEIASLYSATPGIIEAAYAAALKAQGEWAALKPVERGRILRRTAEILREKNRKLSKLETLDTGKALQETLVADAASAADALEFFGGIISGFNGEFVELGGSFAYTRREALGICVGIGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSALALAEAYKEAGLPDGLFNVVQGYGDVGAALVNHRLTAKVSLTGSVPTGRRIMAQAGEQLKHVTMELGGKSPLIVFDDADLESAIGGAMLGNFYSTGQVCSNGTRVFVHKNIRERFIERLVERTRKIRIGDPFDEATQMGPLISAAQRDKVLSYIKKGKAEGATLACGGGVPKLQGFDKGFFIEPTVFADVTDTMTIAREEIFGPVMSVLEFSDEDEVIARANDSEFGLAAGVFTADLSRGHHVIGQIKAGTCWINAYNLTPVEVPFGGYKQSGIGRENGIAALAHYSQIKTVYVEMGKVDSPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ATPL_RICBR
Sequence: MDMVSLKFIGVGCMAIGMLGAALGVSNIFSSLLNSIARNPSATEQLQRMALIGAGLAEAMGLFSFVIAMLLIFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LFTR_YERPG
Sequence: MRVTQLSSQSFIFPSPELALREPNGLLALGGDLTAPRLLAAYQRGIFPWFNPGEMILWWSPDPRAVLFPEDLHISRSMRRFIRHCPYRFTLNHAFADVISACATERDEGTWIGRDVQQAYCQLHALGHAHSLEVWLENELVGGLYGVAVGAVFCGESMFSRADNASKSALMVFCHHFTQHGGELIDCQVLNAHTASLGAVEIPRNFFLQQLSQLQFSPLPAECWLPQSLNFSSAMQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IWS1_NEUCR
Sequence: MSDAASPAGSPAAEPTEHRDEDQVNETHQDDGSNHGGNDEDNDGGNDKDSDVLSEIDENEFGDDYGSRPVDIDENVAMKLKARRKTTTETTKKPKEGRRPKKRSRGDDDVDAADDDGERRPRKVRAEGERRARKEVEEQQAQQEENLTPDERRRRALERAIDAAVKNPTKRRRKKDDIDLEEETDEQIANLKVAMEKACVADNEAREQKQPAVHKLKLLPQVTAILNRTAIQDSVLDPEINFLQSVRYFLEPLNDGSLPAYNIQRAIMSALMKLPINKDVLLSSGIGKVVVYYNKSKSPSADIKRDAERLLGEWSRLILKRTDDYKKRHIEMREIDVGAVKLGQREGGSSQVTLTQRPAGKSRYEIERERALAPEVRNNNRARPVGLPASYTIAPKSTYIPGQAPTDHRPIGHSGHEAFRRMTQKGKGKR
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor iws-1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIHA_SALDC
Sequence: MALPIIIDCDPGHDDAIALVLSLASPELEVKAITSSAGNQTPEKTLRNVLRMLTLLKRPDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSGTAVELMAKTLRESSQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRAIGNPISTIVAELLDFFMEYHKDEKWGFVGAPLHDPCTIAWLLKPEIFTTVERWVGVETQGKYTQGMTVVDYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: GATY_SALPC
Sequence: MFIISGRTMLKKAQQEGYAVPAFNIHNLETLQVVVETAAELRSPLIVAGTPGTFSYAGVGNIVAIAAELAKSWNHPLAVHLDHHEKLADIKMKVAAGVRSVMIDGSHFPFADNIALVKSVVDYCHRYDVSVEAELGRLGGQEDDLIVDGKDALYTHPEQAREFVEKTGIDSLAIAIGTAHGLYTAEPKLDFERLTEIRQRVDVPLVLHGASGLPTRDITRAISLGICKVNVATELKIAFSGALKNYLTQHAEASDPRHYMIPAKAAMKEVVRKVIADCGCEGKL
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: SYE_CLOP1
Sequence: MSYENLANLIFPNIDKTPEYYFEKYPKRDLKEGAKVLRYAPSPTGFQHIGGVFASLINERLAHQSGGIFYLRIEDTDQKREVEGAIDDTIKTMHNFGMDFDEGITGENSEKGAYAPYKQSQRADIYRAFVKDLLRKGLAYPCFMTSEELEALREKQIAEKLTPGCYGEFAKYRDLSPEEAIKRIEAGESYVIRMKSPGNPEKRVVAHDMIKGEVSFPENLQDVVIIKGDGLPTYHFAHAIDDTLMRTTHVIRGEEWLSSLPIHLQMFEVLGVEAPKYAHIPTIMKMDGSSKRKLSKRKDPESAVSYYSEKGYPSQSVIEYLLNIINSAFEEWRAENPDADYHDYKVELDKMSKSGALFDLVKLNDVSKDVICKMKPEVVYDLYTNWAKEYDKEMYDLVTSKEAMMKEVFNIDKEGPKPRKDFAKWDEVREKIFYFFDELFDKETANDVELPKTLELEEAKRIIEAYEKAYNFNTDKDTWFSDLKEVAVELGYATDRKKYKKNPEEYKGMVSDVAGAVRAALTHRANTPDLYTIMQIMGEEAVRERFKKFLSL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.