PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_THESQ
Sequence: MIAANFLLNLFLYPILIKLFRRRRIGQYIRKEGPDLHGYKEGTPTMGGILFVLTGFLFGMISKTTTMVLLGMFLFFLIGFLDDFLSVVRKDSTGLKTYQKALLQTLSALIMLLLIRPETNVDFFGFTIEMGKWYYLFALLVIVGSSNAMNLTDGLDGLAGWIYVSGSIPYWFFLKERGVSEDILLILGAGVLAFLVFNSKPAKIFMGDTGSITLGGVLGTVSVLTKTEFYLVLFFLIPVIETLSVILQVGSFKIFKRRIFRMSPLHHHFELIGWSEEKIVAVFTVFNLVSSLVVLEIFGVIA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAL2_MOUSE
Sequence: MTRKIFTNTRERWRQQSVNNAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLHQTGVAAQGNILGLFPPKTRLPDEDDRTLLNDYRVPSPGPSHGAP
What are the official names of this protein?
T-cell acute lymphocytic leukemia protein 2 homolog, TAL-2.
Protein: OPSD_ALLMI
Sequence: MNGTEGPDFYIPFSNKTGVVRSPFEYPQYYLAEPWKYSALAAYMFMLIILGFPINFLTLYVTVQHKKLRSPLNYILLNLAVADLFMVLGGFTTTLYTSMNGYFVFGVTGCYFEGFFATLGGEVALWCLVVLAIERYIVVCKPMSNFRFGENHAIMGVVFTWIMALTCAAPPLVGWSRYIPEGMQCSCGVDYYTLKPEVNNESFVIYMFVVHFAIPLAVIFFCYGRLVCTVKEAAAQQQESATTQKAEKEVTRMVIIMVVSFLICWVPYASVAFYIFSNQGSDFGPVFMTIPAFFAKSSAIYNPVIYIVMNKQFRNCMITTLCCGKNPLGDDETATGSKTETSSVSTSQVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity (PubMed:8654500).  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8654500).  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: RS7_HELP2
Sequence: MRRRKAPVREVLGDPVYGNKVVTKFINKMMFDGKKSVAEKIIYKAFNKIEEKSGEKGIEVFEKALERVRPLVEVRSRRVGGATYQVPVEVRASRQQSLSIRWILEATRKRNERMMVDRLANELMDAASDKGAAFKKKEDVHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: EZRA_BACAA
Sequence: MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVSTTIPKADKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHGHNDMVRQGYVLDYLEVPKEVRDMTKQLQTCLIDIQELHITEAAEKVENLKTRLDGFYDQLEQEVHARHYVEQKTLSVYEDLEEIRTETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILTKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSLEEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIAEYVDNEQTLS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: MGSA_BRUAB
Sequence: MTQRLRIALIAHDQKKDDMVAFARAHEQALSRYDIVATGTTGGLIQDACPSLNIHRVKSGPLGGDQQIGAMIAEGTVEVLIFFIDPLSPLPHDVDVKALTRLGSVYDIPMALNRATAEKLVRALD
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RL10_STRP1
Sequence: MSEAIIAKKAEQVELIAEKMKAAASIVIVDSRGLTVDQDTVLRRSLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTKTADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAENKEGAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: 5DNU_ECOL6
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAG2_EIKCO
Sequence: MHFTQFMGQASVEQDTFGSSGFTRINVGRNTDITVQINRGFTSHFNRLSKLEAEVREGFVGFSHAVYFFTFFHGAATAFCGINQLIGQAQIHGFFATLAGCIAHPAHCQGQTAGRTNLNRNLVVSTTNTAAFHFHDGFGIVDGFVKHFDCLFALYFLGSLLQSTIHDALVNRFFTVNHQGIHKLGQFNAAELRIRQYVALRDFSTSWHFNFL
What is the function of this protein?
Induces agglutination of neuraminidase-treated erythrocytes.
What are the official names of this protein?
Hemagglutinin 2.
What are the subcellular locations of this protein?
Secreted.
Protein: LSRK_YERPE
Sequence: MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGLLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERLVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPCL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATI1A_ALYOB
Sequence: GLKDIFKAGLGSLVKGIAAHVAN
What is the function of this protein?
Antibacterial peptide with amphipathic alpha-helical structure.  Shows selective growth inhibitory activity against the Gram-negative bacteria E. coli (MIC=25 uM) Has a weak hemolytic activity against human erythrocytes (LC(50)>100 uM).  Is very weakly active against S. aureus (MIC=200 uM).
What are the official names of this protein?
Alyteserin-1a.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Alyteserin-1 subfamily.
Protein: ENO_THESQ
Sequence: MYVEIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGKGVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEIFHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERTAKYNQLLRIEEELGKVAEFRGLKSFYSIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MURG_RHILO
Sequence: MARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSATMGSKNPIAVLGAFWKIWRGVRQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLIHEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTTGNPVRPAVLEAAKTPYAASTGQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALGVAVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAALAAAGGGEVHPQSTLSPERIAALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAIASQKTVSDFKKGTQA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMB_SHEPA
Sequence: MSDVTTAEFNEEGKYLRKVRSFVLREGRLTKGQAQAMEQQWPKIGLDYTPEPIDLVEVFGREADTVLEIGFGMGASLVAMAKAAPELNFIGIEVHKPGVGACLAEAAEAGVTNLRVYHHDAIEVLENSIAEGSLACVQLFFPDPWHKTRHHKRRIVQAPFAELIRSKLKVGGVFHLATDWENYSEHMLEVMTAAPGYKNQSATGDVVERPAHRPLTKFEARGHRLGHGVWDLMFERV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RNPA_CITK8
Sequence: MVKLAFPRELRLLTPSHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HFQ_SERP5
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGGTSNYHHGNNPSAPQQPQQESDDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CHSTA_MOUSE
Sequence: MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTTMPEAEKLRGEKHFPEVPKPTGKMLSDSRPDQPPVYLERLELIRNTCKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRKNRTETRGIQFEDFVRYLGDPNRRWLDLQFGDHIIHWVTYVELCAPCEIKYSVVGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN
What is the function of this protein?
Catalyzes the transfer of sulfate from 3'-phosphoadenylyl sulfate (PAPS) to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides.  Participates in biosynthesis of HNK-1 carbohydrate structure 3-O-sulfo-beta-D-GlcA-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-R, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult.  May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis (PubMed:12213450, PubMed:12358771).  Sulfates terminal glucuronyl residue of the laminin globular (LG)-domain binding epitope on DAG1/alpha-dystroglycan and prevents further polymerization by LARGE1 glycosyltransferase.  Likely defines the chain length of LG epitope, confering binding specificity to extracellular matrix components (By similarity).  Plays a role in down-regulating the steroid hormones.  Sulfates glucuronidated estrogens and androgens with an impact in hormone cycle and fertility.  Has a preference for glucuronyl moiety at the 3-hydroxyl group of a sterol ring rather than the 17-hydroxyl group, showing high catalytic efficiency for 17beta-estradiol 3-O-(beta-D-glucuronate) and dehydroepiandrosterone 3-O-(beta-D-glucuronate) hormones (PubMed:23269668) (By similarity).
What are the official names of this protein?
Carbohydrate sulfotransferase 10, HNK-1 sulfotransferase, HNK-1ST, HNK1ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: YAHV_ECOLI
Sequence: MCDILLNVLNIVFIGIAIILVIIC
What are the official names of this protein?
Protein YahV.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PMYT1_MOUSE
Sequence: MTMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPGGLSRSLPPRPPAKGCIPVSRLFPPRTPGWHQPQPRRVSFLCETSEPLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDRTRKLAEVGGHEKVGQHPHCVRLERAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDILLALDHLHSQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGSAGAGEAQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLAMMLEPDPQLRATAEALLALPMLRQPRPWNVLWYMAAEALSRGWALWQALVTLLCWLWHGLVHPASWLQPPGPPATPPGSPPCSPLLDSTLSSSWDNDSIGPSLSPETVLSRITRRTSTPRGRYIPRDALDLTDVDSEPPRGPCPTFEPRNLLSLFEDSLDPA
What is the function of this protein?
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins.  Mediates phosphorylation of CDK1 predominantly on 'Thr-14'.  Also involved in Golgi fragmentation.  May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect.  May be a downstream target of Notch signaling pathway during eye development (By similarity).
What are the official names of this protein?
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Myt1 kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: HEM6_AGRRK
Sequence: MERPNLPKELPEDIEDKKEAAQGWFQSLRDALCAEFEQLEDELAGPLSDQTPGRFVAKDWQRENGEGGGGRMSMMEGRVFEKVGIHTSTVYGEFSPDFRSQIPGAEEDPRFWASGLSLIAHPVNPNVPTVHMNTRMVVTTSQWFGGGCDLTPMLNRRRTQEDTDSVLFHRAMQIVCDRHKVADYQRYKAWCDEYFYLKHRNESRGIGGIFFDWLHSTEEAGGWDADFAFTRDVGRAFSMVYPRIVRSNFNETWTEEDRDEQLIRRGRYVEFNLLYDRGTIFGLKTGGNVESILSSLPPVVRWP
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_CROS8
Sequence: MSETKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGEYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAINKVDNVQDKAELLPHLQFLGSQMNFLDIVPISAETGMNVDTIAAIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQDMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: KGUA_FRATO
Sequence: MNNYIFIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQLLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEINWQGAQQTRAIYGDRAKSIFILPPSLDELRKRLEKRNTDSKETIDYRMEQVQSEISHADEYDYLLVNDDFSQSLEQLCKYFEQNIQS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB2_SALAI
Sequence: MGIEEKLPAGVLLTSVEKLVNWSRKSSVWGATFGLACCAIEMMAAGGPHYDMGRWGMEVFRASPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPRWVLSMGVCASSGGMFNNYAIVQGVDHVVPVDMYLPGCPPRPEMLIDAVLKLREKIMHEPLGPNGRKMLEARKARGDVPVVPYGSMPSSYRSDKARRAEWTKAVREGREEQLRIENWMKAQPHLQQYEGLKK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VL2_HPV43
Sequence: MVSHTHKRRKRASATQLYQTCKAAGTCPSDVINKVEHTTIADQILKWASMGVYFGGLGIGTGSGTGGRTGYVPLTTGRTGIVPKVTAEPGVVSRPPIVVESVAPTDPSIVSLIEESSIIQSGAPITNIPSHGGFEVTSSGSEVPAILDVSPSTSVHITTSTHLNPAFTDPTIVQPTPPVEAGGRIIISHSTVTADSAEQIPMDTFVIHSDPTTSTPIPGTAPRPRLGLYSKALQQVEIVDPTFLSSPQRLITYDNPVFEDPNATLTFEQPTVHEAPDSRFMDIVTLHRPALTSRRGIVRFSRVGARGTMYTRSGIRIGGRVHFFTDISSIPTEESIELQPLGRSQSFPTVSDTSDLYDIYADENLLNNDISFTDTHVSLQNSTKVVNTAVPLATVPDIYAQTGPDISFPTIPIHIPYIPVSPSISPQSVSIHGTDFYLHPSLWHLGKRRKRFSYFFTDNYVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: T1SF_MYCPN
Sequence: MAEIPIDFPPLKIQEKIATILDTFTELRARKKQYAFYRDYLLNQENIRKIYGANIPFETFQVKDICEIRRGRAITKAYIRNNPGENPVYSAATTNDGELGHIKDCDFDGEYITWTTNGYAGVVFYRNGKFNASQDCGVLKVKNKKICTKFLSLLLEIEATKFVHNLASRPKLSQKVMAEIELSFPPLEIQEKIADILCAFEKLCNDLVEGIPAEIELRKKQLDYYQNFLFNWVQKIRN
What is the function of this protein?
The specificity (S) subunit of a type I methyltransferase (MTase); this subunit dictates DNA sequence specificity.  The single R subunit has multiple frameshifts and is probably not expressed.
What are the official names of this protein?
Putative type I specificity subunit S.MpnORF201P, S protein, S.MpnORF201P, Putative type-1 restriction enzyme specificity subunit MPN_201, S.MpnORFFP.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: RS16_LIMF3
Sequence: MSVKIRLKRMGSKKRPFYRIVVADSRSPRDGRFITSLGTYNPLTTPKQVKFDEDAVMEWLQKGAQPSDTVRNMLQKAGVMKKYHEAKYAKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LEU3_MAGSA
Sequence: MAAKKLLILPGDGIGVEVMAQVRRIIDWMGRKRKIEFEITEGLLGGAAYDVHGTPYPAETLEAALAADAVLLGAVGGPKWDDLPFDKKPERGLLGIRKDMGLFANLRPATVLEALADASTLKAEVVSGLDIMILRELTGGLYFGQPRGIDTLPDGTRKGYNTLVYTTPEIQRIGRVAFDLARKRNKKLCSVDKANVLECTVLWREEMIKLQKEEFPDVELTHMYVDNAAMQLVRNPKQFDVMVTENMFGDILSDCAAMLTGSLGMLPSASLGEADAQGKRKALYEPVHGSAPDIAGKDMANPLATIMSFAMCLRYSFDMAAEADLIETAVKNVLKGGLRTADIMQPGKAKVSTTVMGEAVVRELDKLNA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.