PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_HALHL
Sequence: MRDLLNLFKQPGAQLEDFDAIRIGLASPEMIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVVCEKCGVEVTVAKVRRERMGHIDLASPVAHIWFLKSLPSRIGLLLDMTLRDVERVLYFEAYIVIEPGMTPLEQGQLLTDEQYLEAVEEHGDEFDARMGAEAVLEILKGMDLEAEARRLRDDIEATGSESKIKRLSKRLKLLEAFLESGNKPEWLIMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPTLRLHQCGLPKRMALELFKPFIFSKLQRRGLATTIKAAKKMVERETGEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAYNADFDGDQMAVHVPLSLEAQLESRAMMMSTNNILSPASGEPIIVPSQDVVLGIYYMTRERVNARGEGMRLAGVEEVHRAYQTGAAELGARVEVRIRERVFDDSGEMVERVQRRQTTIGRALLFDIVPDGLPFEAVDRELDKKGVSGLVNACYRRVGLKGTVVFADQLMYTGFFYSTKAGVSIGVDDMEVPTDKEEALRSAEEEVREIEDQYASGLVTSGERYNKVVDIWAHTNDQVAGAMMEKMGKETVVDAEGNETEQKSLNSIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVSQDLVVTEEDCGTTDGLVQTPIIEGGDVVETLAERVLGRVVAEDVAVPGSTDIAVEAGTLLDEDWVERLERMGVDEIKVRSAVTCETRHGVCAKCYGRDLARGHGVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAVSQVEVRNTGKARLHNIKTVQHHSGSYVAVSRSGELTVMDEYGRERERYKIPYGAVLSVGDEDPVEAGQVVANWDPHTHPIVTEVDGYVRFHDFVEGVTVQREVDEVTGLSSLVVTDPKSRGTGEHKRQVTNANGKVTEERVAYKDLRPMIKLVDGDGNDLNIAGTQIPAHYYLPAGAIVSLEDNAEVRVGDALARIPQEASKTRDITGGLPRVADLFEARKPKEPAILAEASGTVGFGKETKGKQRLIITKADGETHEELIPKWRNVTVFEGEHVEKGETIADGEPNPHDILRLLGVTKLAEYIVQEIQDVFRLQGVGINDKHIEVIVRQMLRKTIVSDPGDSLHLKGEQVDRAKLLEENEQLQAQDKQPAQWEPSLLGITKASLSTESFISAASFQETTRVLTEAATRGIRDDLRGLKENVIVGRLIPAGTGFAYHAARRQEAPAPAATPEQQAEEVFASLGQGEGEGPSPSDEASGPEVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MMOC_METCA
Sequence: MQRVHTITAVTEDGESLRFECRSDEDVITAALRQNIFLMSSCREGGCATCKALCSEGDYDLKGCSVQALPPEEEEEGLVLLCRTYPKTDLEIELPYTHCRISFGEVGSFEAEVVGLNWVSSNTVQFLLQKRPDECGNRGVKFEPGQFMDLTIPGTDVSRSYSPANLPNPEGRLEFLIRVLPEGRFSDYLRNDARVGQVLSVKGPLGVFGLKERGMAPRYFVAGGTGLAPVVSMVRQMQEWTAPNETRIYFGVNTEPELFYIDELKSLERSMRNLTVKACVWHPSGDWEGEQGSPIDALREDLESSDANPDIYLCGPPGMIDAACELVRSRGIPGEQVFFEKFLPSGAA
What is the function of this protein?
Responsible for the initial oxygenation of methane to methanol in methanotrophs.  It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.  The component C is the iron-sulfur flavoprotein of sMMO.
What are the official names of this protein?
Methane monooxygenase component C, Methane hydroxylase, Methane monooxygenase reductase, MMOR.
Protein: DTD_DESVH
Sequence: MRLVVQRVLEAGVRVDDTPVATIGTGLLVLAGFGKDDDETLPDSRRWNAMCDKLIDLRIFPDAEGRMNRSLREHGGEVLLVSQFTLYADLRRGRRPSFQTAAPPDTARNLYERLVHDIDARLPGRVSSGIFGALMHVSLINWGPVTLCLDDAELFPEASVAG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_DESVH
Sequence: MNTLECLAVAVALAMDAFAVAIATGIRLREVSPRQTFRLAFHFGLFQALMPVAGWTLGLTVRGYIEQWDHWLAFGLLLYIGVRMMREAFEETEENDDRCDPTRGLTLIMLAVATSIDALAVGLSLSVLGIDIVTPAIVIGVVCLLFTATGLHLGRMLSRAESLGRRAALAGGVVLIGIGLRILYEHGVFDTAATLARSVLG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL1_SULTO
Sequence: MLASKDSLVEALKVALNPENNPKRNFTQSVELIVTFKGIDMKKGELKLREIVPLPKEPSKPRKVLVIPAFQQIESAKKAEPNVLLTKEELQKLQGQKRAIKKLARQNDWFLVAQDSMALVGRILGPALGPRGKFPTPLPNAADITEYILRFKRSTLVKTKDQPHVQVFIGTEDMKPEDLAENALAVLNTIENKAKVEANLRAIYVKTTMGKIVKVELKK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PUR7_PARL1
Sequence: MSRRRRVYEGKAKVLYEGPEPGTLIQHFKDDATAFDAQKRATIEGKGVLNNRISEFIFTRLNEIGVPTHFIRALNMREQLIREVEIIPCEVVVRNVAAGSLSKRLGIDEGTVLPRSIIEFYYKNDELHDPMVSEEHITAFGWATPQEIDDMMALALRINDFLTGLFLGIGIRLVDFKVEFGRLYEGEMVRVVLADEISPDCCRLWDTRTNDKMDKDRFRRDMGGLIEAYSEVARRLGILFENEPKRSGPKLVK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DSBA_BURCE
Sequence: MKKLLSTLLLSLGLAAGLAQASPAAPASGKDFEVMKSPQPVSAPAGKVEVIEFFWYGCPHCYEFEPTIEAWVKKQGNNIDFKRVPVAFRDDFLPHSKLFYAVSALGISEKVTPAIFNAIHKQKNYLLTPQAQADFLATQGVDKKKFMDAYNSFSVQGEVNQSAKLLKDYAIDGVPTVVVQGKYKTGPAYTNSIPGTAQVLDFLVKQVQDKKL
What is the function of this protein?
Involved in disulfide-bond formation.  Acts by transferring its disulfide bond to other proteins.  Involved in the production of protease and alkaline phosphatase, motility, metal resistance, and multi-drug resistance.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ORPO_POTOR
Sequence: HGGYKPTDK
What is the function of this protein?
Vasoconstrictor.
What are the official names of this protein?
Orpotrin.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHM_PROM3
Sequence: MNETLLKCTTRHVRIFTARVENNDLVPDPDQLTLDLDPDNEFLWTESVIKEIQQRFAELVASHAGGELSDYNLRKIGSELEGTIRKLLQAGKLSYNPECRVLNYSMGLPRTPELL
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MNMG_ACIB3
Sequence: MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLVREIDALGGAMALAADKGGIQFRILNSRKGAAVRATRAQADRVRYKAAIRETLENQANLDIFQQAADDLIVEGDTVKGVVTQMGIRFDAKTVVLTTGTFLGGVIHVGLEKSSGGRAGDPPSIALAQRLRELKLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQVNCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFSDKDSHQVFLEPEGLDTHELYPNGISTSLPFDVQFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETKAINGLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWEQEEWTPKRDQAYMGVLVDDLITLGTKEPYRMFTSRAEYRLMLREDNADQRLTTIGRELGLVDDVRWAAYCEKMEAVERETSRLQHVWAAPNNPMGKKFVEMTGADLSKECSAIDLLKRPNINFGQIAELTGSEVSQQVGEQIEIAVKYEGYINRQHEDVAQLKRLEETKIPADFDYDVVSGLSREITQKLKTVRPETLAQASRIPGVTPAAVQLVMITIRKNNMTKKTA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYO17_ARATH
Sequence: MVGPVNIIVGSHVWIEDPGAAWIDGEVVKINGEEVHAHTTNGKTVVANIANVFPKDTEAPPGGVDDMTKLSYLHEPGVLNNLAMRYELNEIYTYTGNILIAVNPFQRLPHLYDTHMMEQYKGAGFGELSPHVFAIAEVAYRAMINEGKSNSILVSGESGAGKTETTKMLMRYLAYLGGRSGVEGRTVEQQVLESNPVLEAFGNAKTLRNNNSSRFGKFVELQFDNCGRISGAAVRTYLLERSRVCQISDPERNYHCFYLLCAAPPEEREKFKLGDPKLFHYLNQSKCYKLDGVDDTEEYLATRRAMDIVGISEEEQDAIFRVVAAILHLGNVNFAKGKEIDSSVLKDEKSRYHLDVCAELLRCDAKKMEDALIKRVMVTPEEVITRTLDPDSATGSRDALAKTIYSRLFDWLVDKINNSIGQDPNSKTIIGVLDIYGFESFKINSFEQFCINFTNEKLQQHFNQHVFKMEQEDYTKEEINWSYIEFVDNKDVLELIEKKPGGVIALLDEACMFPKSTHETFAQKLYQTFKNYKRFTKPKLSRTSFAISHYAGEVTYQADLFLDKNKDYVVAEHQDLLIASSDTFVAGLFPRLPEETSSKTKFSSIGSRFKLQLQSLMETLSSTEPHYIRCVKPNNVLKPAIFENVNVIQQLRCGGVLEAIRISCAGYPTKRTFYEFLNRFGVLAPEVLEGNYDDKVACKMLLDKIGLKGYELGKTKVFLRAGQMAELDARRAEVLGNAARRIQRQSRTFIACKEFRALRGAAIVLQSNCRGKLACNLYEEMRRQAAAVKIQKIFRRHIARESYLRIRHSTITVQTALRGMVARNEFRFRKQMKAATIIQARLRSHLTHSYYKQLQKAALSTQCGWRSRVARKELRTLKMAARDTGALREAKDKLEKRVEELTWRLQLEKRQRTELEEAKTQEYAKQQEALETMRLQVEEANAAVIREREAARKAIEEAPPVIKETPVLVEDTEKINSLTSEVEALKASLQAERQAAENLRKAFSEAEARNSELATELENATRKADQLHESVQRLEEKLSNSESEIQVLRQQALAISPTSRTMATRSKTMLLPRTPENGNYLNGGTKTTPDMTLAVREPESEEKPQKHLNEKQQENQDLLVKCISQNLGYNGDKPVAACVIYKCLLHWRSFEVERTSVFDRIIQTIATAIEVPDNNEVLAYWLSNSATLLLLLQRTLKATGAASLTPQRRRTTSASLFGRMSQGLRGSPQSAGLSFLNRQGLTKLDDLRQVEAKYPALLFKQQLTAFLEKIYGMIRDNLKKEISPLLGLCIQAPRTSRASLVKGRAQANAVAQQALIAHWQSIRKSLNSYLNLMKANNAPPFLVRKVFTQIFSFINVQLFNSLLLRRECCSFSNGEYVKAGLAELEQWCIEATDEYAGSAWDELRHIRQAVGFLVIHQKPKKTLDEITRELCPVLSIQQLYRISTMYWDDKYGTHSVSSDVIANMRVMMTEDSNNAVSSSFLLDDDSSIPFTVEDISKSMQQVDVNDIEPPQLIRENSGFGFLLTRKEGSTS
What is the function of this protein?
Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation.  Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables.  Involved in the tip growth of root hair cells and in the elongation of trichome stalk and branches.  Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development.  Acts as the primary contributor to ER streaming with a major role in the movement of Golgi bodies.  Required for development of pavement cells, trichomes, and stigmatic papillae.
What are the official names of this protein?
Myosin-17, Myosin XI K, AtXIK.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with peroxisome, cytoplasmic vesicles, endomembrane vesicles, endoplasmic reticulum and/or organelles.
Protein: MYF6_TAKRU
Sequence: MMDLFETNTYLFNDLRYLEEGDHGPLQHLDMSGVSPLYNGNDSPLSPGQDNVPSETGGESSGDEHVLAPPGLRSHCEGQCLMWACKICKRKSAPTDRRKAATLRERRRLKKINEAFDALKRKTVANPNQRLPKVEILRSAISYIERLQDLLQTLDEQERSQSGASDTRNDKEQNRPSGGDYRWKKASNTWPTSADHSAIINQRDGNCESSATSSLLCLSSIVSSISDDKTNLRQGVQED
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenic factor 6, Myf-6, Muscle-specific regulatory factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFM2_YEAST
Sequence: MFDPLDLYTPDDIQVEALQFNLAEREPKDPCSPQRDEILTAVDEEESDDDDTIIDNLDLPSVKYAPPEVILCILILLKPDRQVNFNQETGKNKSVLEVCKSHGLEPDLLKRLLTWYTEEWPNKRLNSLEKICNKIPMLRFTVSKELLLGYYTSVLKKYNNSCGLNEEIIQELLKELSSRISENCGRTAQPSIVRYFELRNLSTSIPLHEPSLTADNLGWKTWGSSLILSQLVVDHLDYLHTTNVNMLANSDIKQIKVLELGAGTGLVGLSWALKWKELYGTENIEIFVTDLPEIVTNLKKNVSLNNLGDFVQAEILDWTNPHDFIDKFGHENEFDVILIADPIYSPQHPEWVVNMISKFLAASGTCHLEIPLRAKYAKEREVLKLLLKESDLKVVEERHSEGVDDWGAVKYLYRQIVRN
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 2 (EFT1/EFT2) at 'Lys-613' and methylates elongation factor 3A (YEF3).
What are the official names of this protein?
Protein-lysine N-methyltransferase EFM2, Elongation factor methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family.
Protein: IDI_PAEAT
Sequence: MNATEMVVLLDDAGTPIGEAPKAGVHTLDTPLHLAFSCYLINDVGEVLLTRRSPEKKTWPGVWTNSFCGHPGPGEEFEDAILRRAQFELGVDANKIELVLPHFRYRAIDPTGIVENEVCPVYVARITGVLNPNPAEVADWAWISPALLADALEHTPSAFSPWLGLQFPQLLEANALPLQAGAEA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_ANAMF
Sequence: MSMSGSKKDVESEKQKALDAAISQIERAFGRGAIMKLKQHPAEKMDSVSTGSIALDAALGIGGLPKGRIVEIFGPESSGKTTLALHVIAEAQKQGGNCAFIDAEHALDTVYARKLGVNVGDLIVSQPDTGEQALHIVEYLVCSGAIDVIVVDSVAALTPRAEIEGDMGDQHMGLQARLLSHALRKLTSVVSKANCILVFINQIRIKIGVIYGNPEVTTGGSALKFYTSIRLDIRKVSAIKDKDNVIGNQTRVKVVKNKVAPPFKQAEFDIVYNEGISKLGEIVDMGVKFGFVEKSGAHYSYGAVKLGQGRENAKGYLKSNPDIANELEQKIRACLAESMHSSDLFAVDERTDVLEEEVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4799_PSEA7
Sequence: MNVSKPEQRTLHALAQGGHIAFFRDASGKVTQVECYNRDGHLLLDCTLAVFARLKSKRLIHSSQGRPYRISMAGLKAVRPQADNR
What are the official names of this protein?
UPF0386 protein PSPA7_4799.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: FDHE_ESCF3
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYCCI_CHICK
Sequence: MLAVDTGLVEEWLSEFKTLPEASISSYATNLKDKTALISSLYKVIQEPQSELLEPVCHQLFEFYRSGEEQLLRFTLQFLPELMWCYLAVSASRDLQSSGCIEALLLGVYNLEIVDKEGHSKVLSFTIPSLSKPSVYHEPSSIGSMALTEGALSQHGLSRVVYSGPHPQREMLTAQNRFEVLTFLLLCYNAALSYMPAISLQSLCQICSRICVCGYPRQQVRKYKGVNSRIPVSSEFMVQMLTGIYYAFYNGEWDLARKAMDDVLYRAQLELYPEPLLVANAIKASLPQGAMKSSKEGTKCIQVEITPTSSRISRNAVTSMSIRGHRWKRHGNADLGIEEELIEVSETDEGFYSRAASSTSQSALSNSSNTSSKNLLGKSQRRSGGSKAAGREKEGETCREHLSRKQTQRALSENLELVSLKRLTLTTSQSLPKPGSHSLARTTTTVFSKSFEQVSGVTVANNRGGVSGTEANRFSACSLQEEKLIYGTERTDLPVLSKQPNQQRPPSISITLSTD
What is the function of this protein?
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.  The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis.
What are the official names of this protein?
Hyccin, Down-regulated by CTNNB1 protein A.
What is the protein family that this protein belongs to?
Belongs to the Hyccin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane.
Protein: CRP1_YEAS7
Sequence: MSSELMFNYTFSWPAGPKDVILTGTFDDWRGTLPLVKTAKGNFEITMPVKLANKDDTFQFKFIVDGVWCVSDSYKKEHVSEGIENNFLQITDLVETQEVAGASRIPEAGGLLCGKPPRSAGPPSTSNRKKNKRNNKKRRSKLKKKSTKNNKKSNESLDDNEEEDGVTGTTTEDVTGTSREETPLAEPTNVSKEAPGNFHILPIDQSADTTQSNGIIGGPGPVLVPNPGEIKEFTEIRDVDARELNERLNKKEEVPEPVAGPIVESSVTEKSPALPQADDPIVETKEVAHNVQELTPQVEAVTPLINEPEPLPTPEAQISIPESSKVEPVEGSLQSKLVEKRESTEGVLDGSKKVENKAKKDEEVFTLDPIVNKAPKLPLTDEQTAEGRKSPAVSEEKEKKKKQEKGSKEVKRSETSKEKKPSAKEVKKQTVKAPKKQTASPLSSSTEEPKKKKTGFFGKLKKLFK
What is the function of this protein?
Cruciform DNA-binding protein which exerts an enhancing effect on the cleavage of cruciform DNA (X-DNA) by endonuclease VII from bacteriophage T4.
What are the official names of this protein?
Cruciform DNA-recognizing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRP1/MDG1 family.
Protein: ALR_HAHCH
Sequence: MRPSRALIDLDALRHNIRLLNSIAHNARCAAVIKADAYGHGAVEIARALKGEAPKLAVACYDEAVSLREAGVTTPLLVLEGFYSSEELADSTRWCDIEWVVHDMEQLDMLSEVAPLRKAGPDSTRMQTWIKLNTGMNRLGLPLNKLAHVAEKLQQFPGLSVIGLMTHFACADELDSLLQQRQWRAFQAGMQAAGANGWSYSSANSAALLQYPETHLDWVRPGIAMYGASPMADKTGADFGLKPVMTFESRLIATRELQAGDSIGYGAAWTADAPTRMGVVAVGYGDGYPRQMQNGAPVAVCGKRTKIIGRVSMDMLTVDISHIPEARIGSEVELWGGTVSADEVAGYASTISYTLFTGMTSRVPRVYINRSEVV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: COX2_LATCH
Sequence: MAHPSQLGLQDAASPVMEELLHFHDHALMIVFLISTLVFYIILAMMTTKMTDKYILDAQEIEIVWTLLPAIVLILVALPSLRILYLIDEVENPHLTIKAMGHQWYWSYEYTDYEELSFDSYMTPLQDLNPGQFRLLETDHRMVIPMESLIRVLISAEDVLHSWAVPALGVKMDAVPGRLNQITFMISRPGLYYGQCSEICGANHSFMPIVLEAIPLDPFEDWSSSMLEEAX
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FPPS_GIBFU
Sequence: MAQQTTLQEFNSVYPKLEEALLDHARSYKLPQEQLDWYKRSLEVNPLGGKCNRGMSVPDSVSLLLEKPLTEEQYFQAATLGWMTELLQAFFLVSDDIMDSSITRRGQPCWYRQEGVGMIAINDAFMLESAIYTLLKKYFRSHPAYFDLIESFHETTFQTELGQLCDLLTAPEDNVNLDNFSLEKYSFIVIYKTAYYSFYLPVALALHQLNLATPSNLKQAEDILIPLGEYFQIQDDYLDNFGKPEHIGKIGTDIKDNKCSWLVNQALAVATPEQRKILEENYGRKDDEKEKVVKKLYDDLNLEQRYLDYEEKVVGQIRERIANIDENDGLKKTVFEAFLAKIYKRSK
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_DESA1
Sequence: MGFDYQRAVMLQRILSERVLAELDSFPRIDPSRIRSVAGVDASYRGGVQVGSAVLMDYRAKMPLAYTCLTSKPPIPYVPGLLAFREAPVYIKALHRLPAKPDIILVDGHGLSHPRAFGIATHIGLVLSTPSIGVAKKPLYGEVEEVNGRKLVRAHGRIVGEVVETNQGSEIYVSIGYLIRLEDAVEVVRHLMEPGLKLPLPIHLADNYSRSKCIKELRL
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_ECO7I
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGFLA_BOVIN
Sequence: MDLIRGVLLRLLLLASSLGPGAAPLRSALRKQGKVGPPLDIILDALNCSAFSIQWKMPRHPPSPIMGYTVFYSEVGIDKSLQERSYGVPPGLDTPTSGRLDHQMIFEEVIGDLKPGTEYRVSMAAYSQTGKGRLSSPQHVTTLPQDSCLPPTAPQQPHVIVVSDSEVALSWKPGESEGSSPIQYYSVEFTRPDFDKSWTSIREQIQMDSMVIKGLDPDTNYQFAVRAVNPHGSSPRSQPSSTIRTARPEESGSGRYGPHYATDTEAGEDDDTFEDDLDLDISFEEVKPLPAIKEGNKKFFVESKMAPRPNPMTVSRLVPPTPASLPTTAVAPQPTPVDRKGKHGVAVMPRLFDTSCDETVCSADSFCVSDYTWGGSRCHCNLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAVIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVTLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQALTVNGKRLDLRPWPLGKALSGADVGECSSGICDEASCINGGTCMASKADSYICLCPLGFRGRHCEDAFTLTIPQFKESLRSYAATPWPLEPRHYLSFMEFEVTFRPDSEDGVLLYSYDTGSKDFLSINMAGGHVEFRFDCGSGTGVLRSEEPLTLGHWHELCVSRTAKNGILQVDKQKAVEGMAEGGFTQIKCNSDIFIGGVPNYDDVKKNSGILKPFSGSIQKIILNDRTIHVKHDFTWGVNVENAAHPCVGSPCAHGGSCRPRKEGYECDCPLGFEGLHCQKAITEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNAFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK
What is the function of this protein?
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception.  Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse.  Promotes matrix assembly and cell adhesiveness.
What are the official names of this protein?
Pikachurin, EGF-like, fibronectin type-III and laminin G-like domain-containing protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Synaptic cleft. Presynaptic active zone. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals.