PharMolix/UniProtQA huggingface dataset:
Protein: RL27_HELPG
Sequence: MAHKKGQGSTQNNRDSAGRRLGVKKFGSEFVRAGNIIVRQRGTKMHPGNNVGMGKDHTLYALIDGVVKFEHKDRNRKKVSVVSQNFGE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SSUD_AZOVD
Sequence: MSLNVFWFLPTHGDGHYLGTAEGARAVDHAYLQQIAQAADRLGFGGVLIPTGRSCEDSWLVAASLIPVTRRLKFLVALRPGIISPTVAARQAATLDRLSGGRALFNLVTGGDPEELAGEGLHLSHAERYEAATEFTRIWRGVLSGETVDLQGKHIQVEGARLLFPPLQQPHPPLYFGGSSEAAHELAAEQVDLYLTWGEPPAAVAEKIADVRARAARHGRTVRFGIRLHVIVRETTEEAWEAADRLIGHLDDETIAKAQASLARFDSVGQQRMAALHGGSKENLEVSPNLWAGVGLVRGGAGTALVGDGPTVAARMKEYAALGIDTFVLSGYPHLEESYRVAELLFPHLDLARPAGVEGRGQVSPFGEVLANDILPKAAAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: PLSY_BORPE
Sequence: MPATMVLTAPSLLSSSALIVLAYLIGSIPFAVVVSKLMGLQDPRSYGSGNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLARALVPELSWGAYALVALAVFLGHLYPLFLRFKGGKGVATALGVLMAIEPWLAVATIATWLIVAVFSRYSSLAALVAAFFAPVYYVFGSGAAWHARLEVGLAIAVISALLFYRHRANIARLLKGTESRIGKKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRIB_SHIFL
Sequence: MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: PHS_SHESA
Sequence: MTALTQMKCEACQADAPKVTDAELAELIRMVPDWGVQVRDGIMQLERVYKFKNFKLAMAFTNKLADLAEEEFHHPGILTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: TRHO_YERPY
Sequence: MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTLEDAKTFRDNLYSQFVKLGVFGRVYVAKEGINAQISVPANRYDEFKIALFASHPALDQVRLNVAHEDDGKSFWVLRLKVRERIVADGIDDDSFDPANIGHYLKADQVNQMIDDPDTLFVDMRNHYEYEVGHFENAIEVPSDTFREQLPMAVDMLQHDKEKNIVMYCTGGIRCEKASAYMLHNGFKNVYHVEGGIIEYARKAKEQGLPLKFIGKNFVFDERMGERISDDVIAHCHQCGTPCDAHTNCKNDGCHLLFIQCPVCAAKFEGCCSQICQEELKLPQEEQRSRRAGRENGIKIFNKSKGLLQATMHIPSPEKSADEK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: APT_ALIB4
Sequence: MSEKNVLDENSKNILLDSIRTINDYPKPGIIFKDITTLLNNKNAFNLLMDHLEERYKSYNLDYIAGVEARGFFFASALASRLKIGFVPVRKKGKLPSTTICEKYELEYGFSEVELHLDAFNNEKNVNVLLIDDIIVSGGTAYAAANLIKKLNVNLVESCFLMNIAILDGAKKLSEISPVYCVLEI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_THEMA
Sequence: MSLKFDFSNLFEPNISGGLTDEDVKSVEEKVTSAVRNFVENTPDFAKLDRSWIDSVKSLEDWIINFDTVVVLGIGGSGLGNLALHYSLRPLNWNEMTREERNGYARVFVVDNVDPDLMSSVLDRIDPKTTLFNVISKSGSTAEVMATYSIARGILEAYGLDPREHMLITTDPEKGFLRKLVKEEGFRSLEVPPGVGGRFSVLTPVGLLSAMAEGIDIDELHEGAKDAFEKSMKENILENPAAMIALTHYLYLNKGKSISVMMAYSNRMIYLVDWYRQLWAESLGKRYNLKGEEVFTGQTPVKALGATDQHSQIQLYNEGPNDKVITFLRVENFDREIVIPETGRAELSYLARKKLSELLLAEQTGTEEALRENNRPNMRVTFDGLTPYNVGQFFAYYEAATAFMGYLLEINPFDQPGVELGKKITFALMGREGYTYEIKERSKKVIIE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.  Does not have phosphomannose isomerase (PMI) activity.  Isomerization proceeds through a cis-enediol-based mechanism.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, TmPGI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTC6_DEBHA
Sequence: MISYTYITALSILVLNVLNVACTSVDDWPNLSPQIEIALRSQRDIGKYISIDQVTGMGVSLNTLVFDKDGYTLDALNDVSTLLDVGVQTLMINLYWNEFTQKWQLCPAPFPANISSDITTSKELYWDGRTYKCEASLTVDSLVRTINTYLAETNTNIKVNMVHLLFHLKSIRIDPPSGNVSSSEIKDYISTFQPTDSHFVALNNATLNDTVSSFGTSLFTPSDLSSYRKSNYRKGDKVGFYNETRKSFPNLNTFLLLDYKRVMTTVIANDLVKSQYTYNVTSSDKKSVFLEGSGVDTTVASLSDPDAVSQCNELIHYNQDNIEVFDNISLKEHFRIVVDDNGTSFTNVTFSDFVRCGFSPILNASYYNVYNDEEGVSEIDGSLSDIVDNFIPLSFWSWAENQLIEPNRGLNISDSTDTDNDEERDDNDNDDPLVRRDMDYKSSHTAFKCVVLDENGWKVSDCYSRQPIACQKSGSPNDWHIDVKTKREYFTAYKDDSCPDDYNFGIPSSSIEMLALMSYIERENISYPVWIDMNDITVPDCFVTGGPYATCPYQMTVTRLKLAGLIAPSFIVAVVILALILCEKIFRTNPIQSNRKRHWKKAINKYVEKYDYEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RIR2_HELPY
Sequence: MEVSRKKIYNPNSTESVNERKIFGGNPTSMFDLNKIKYQWADHLWKTMLANTWFAEEVSMNDDKRDYLKLSAEEKIGYDRALAQLIFMDSLQANNLIDNINPFITSPEINLCLVRQAYEEALHSHAYAVMVESISANTEEIYDMWRNDMQLKSKNDYIAQVYMELAKNPTEENILKALFANQILEGIYFYSGFSYFYTLARSGKMLGSAQMIRFIQRDEVTHLILFQNMINALRNERADLFTPQLINEVIGMFKKAVEIEALWGDYITQGKILGLTSSLIEQYIQFLADSRLSKVGIAKVYGVQHPIKWVESFSSFNEQRSNFFEARVSNYAKGSVSFDDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: RL32_SHESM
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGEVHMRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RS20_OCEIH
Sequence: MANIKSAIKRVEVNEKKRVSNSKQLSAMRTEVKRVEKAVEANDTDNAKSLFQSASKHIDKAAQKGIIHQNAANRQKSRLANKINAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RAB12_HUMAN
Sequence: MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPHVRCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.  Involved in autophagy (By similarity).
What are the official names of this protein?
Ras-related protein Rab-12.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome.
Protein: MRAZ_OLEA2
Sequence: MSFKGRSYRSLDPKGRLMLPPEVRDALLAVSPEGRVSLTTFDGCLVAYTPEDWEKFEAGFARIKNPSRKMRDFRRLVIGGVEELCVDKQGRVKLSRAHMEYAGITKKVVIVGQGSRFEIWSEEELEAVIGQDFGDVTDELAESGVDFPI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ADAD_ASPNG
Sequence: MSSVTLTTTTTTTSTPPKPTPKDEPQEQIYTPWRLFIYDIWVLGIVSTLAWGCRISTYLIPLFRSNVGKKHLDIGAGTGYYLNQARISSTTQLTIVDNETHALNVALARCKHPVTQTHGIVTDILQPSPFPETYLTNNDQKFDSVSMYYLLHCLPVPVASKCKIFTHLKKYMTEDGVVHGANVLGKGVRKDNWFARIIRRGCLNHGVFHNEEDNAYEFERALRENFWEVETWVVGSVFVFRAKRPILDA
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of the linear tetracyclic TAN-1612 neuropeptide Y receptor antagonist (PubMed:21866960).  The decaketide backbone of TAN-1612 is synthesized by the non-reducing polyketide synthase adaA via condensation of one acetyl-CoA starter unit with 9 malonyl-CoA units.  The FAD-dependent monooxygenase adaC then performs hydroxylation at C2 while the polaketide chain is still attached to the NRPKS adaA (PubMed:21866960).  The alpha-hydroxylation step at C2 appears to be crucial for the following C18-C1 Claisen cyclization and release of the C9-hydroxyl version of TAN-1612 from the NRPKS adaA, two steps performed by the lactamase-like protein adaB (PubMed:21866960).  Finally, the O-methyltransferase adaD performs the C9 O-methylation to complete the biosynthesis of TAN-1612 (PubMed:21866960).
What are the official names of this protein?
O-methyltransferase adaD, 2-acetyl-2-decarboxamidoanthrotainin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: FOXL1_MOUSE
Sequence: MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGRVEPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRTRVEPPESEVGCDVGSPDLATALPTRAPDRSQSPAVGTARPALLPWPGPEPRDPDADLTVQGAGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEAPGIPKPVPGALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFLSYFPLQVPEATVLRFH
What is the function of this protein?
Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium.  Target gene of the hedgehog (Hh) signaling pathway via GLI2 and GLI3 transcription factors.
What are the official names of this protein?
Forkhead box protein L1, Forkhead-related protein FKHL11, Transcription factor FKH-6.
What are the subcellular locations of this protein?
Nucleus.
Protein: TWIST_DROME
Sequence: MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQHHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNNTSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQQQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWRMEGDAQHQKA
What is the function of this protein?
Involved in the establishment and dorsoventral patterning of germ layers in the embryo.
What are the official names of this protein?
Protein twist.
What are the subcellular locations of this protein?
Nucleus.
Protein: ESTA_BACSU
Sequence: MKFVKRRIIALVTILMLSVTSLFALQPSAKAAEHNPVVMVHGIGGASFNFAGIKSYLVSQGWSRDKLYAVDFWDKTGTNYNNGPVLSRFVQKVLDETGAKKVDIVAHSMGGANTLYYIKNLDGGNKVANVVTLGGANRLTTGKALPGTDPNQKILYTSIYSSADMIVMNYLSRLDGARNVQIHGVGHIGLLYSSQVNSLIKEGLNGGGQNTN
What is the function of this protein?
Active toward triacylglycerides with a preference for esters with C8:0 acyl groups; barely active on C18:1 or C18:4 substrates.  Active against p-nitrophenylesters with fatty acid chain lengths from C6 to C18.
What are the official names of this protein?
Lipase EstA, Lipase A, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GSTM2_MACFU
Sequence: MPMTLGYWNIRGLAHSIRLLLEYTGSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGETEKEKIREDILENQLMDNRMQLARLCYDPDFEKLKPEYLEGLPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Participates in the formation of novel hepoxilin regioisomers (By similarity).  Has activity toward aflatoxin B(1)-8,9-epoxide (AFBO) (By similarity).
What are the official names of this protein?
Glutathione S-transferase Mu 2, GST class-mu 2, GSTM2-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFL_ECOLI
Sequence: MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQIGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSSAPFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPESLEHAVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHLTPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWPKHHEQSPAARNFRIHLLNALR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YnfL.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: FOS_PIG
Sequence: MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSVNFIPTVTAISISPDLQWLVQPTLVSSVAPSQTRAPHPYGVPTPSAGAYSRAGAVKTMPGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLSGGLPEAATPESEEAFTLPLLNDPEPKPSVEPVKKVSSMELKAEPFDDFLFPASSRPGGSETARSVPDMDLSGSFYAADWEPLHGGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL
What is the function of this protein?
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.  On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.  Has a critical function in regulating the development of cells destined to form and maintain the skeleton.  It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity).  In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A.  This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Protein c-Fos, Cellular oncogene fos, Transcription factor AP-1 subunit c-Fos.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity).
Protein: RL15_STRPC
Sequence: MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIVRAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: KTHY_NEOSM
Sequence: MFIVLEGIDGSGKSTQVKLLSKFLAKDGYPCVLTREPGGTSFAESLRSMILHDPIDPMARLLLIVSARVDHYNKVILPALKEGKVVVCDRFIYSTLAYQGYGDKIDLQTILDLHRLSGCLVEPDLTLLLLGSGHKKLGRDNFERMPREYLSNVCMGYEKIARMYPNIHVIKCMGVGRTSEEIVKIVQGKISEKQTSSCR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: URM1_CHICK
Sequence: MAAPVSLQVEFGGGAELLFDGVKKHQVTLPSQPEPWDIRNLLKWIKQNLLKERPELFMQGESVRPGILVLINDADWELMGELDYKLQDQDNVLFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_METMP
Sequence: MIITVGGLPGTGTTTTSKLLSEKYGLNHVCAGFIFRDMAKEMNMTLQEFSSYAETNTEVDNEIDRRQVEAAQSGDLILEGRLAGWILKRSDIKPDLSIWLKADPMVRCIRISERENENVDLALEKMISREASEKKRYKEIYNIEIDDLSIYDLTIESSKWDAKGVFNIIEKAIDNLKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_SHELP
Sequence: MLKPLSQLVCALPLVVAASSYADDSAALKDKLAKLDNLKANFSQQVTDVNNKVIQQGTGTFALAVPNQFYWHLTQPDESLIVADGRDVWIYNPFAEEVSVLDFNQAINASPIALLVHRDDATWQAYQVKRQDDCYQITPKAVDASVTGVEVCFKDEQLEVMKLTDQQGNLSVFNLSAQAPLKDADASLFQFTVPEGVDIDDQRLKALD
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y2847_VIBVY
Sequence: MSKNQLPSYQVVADEMKMATLAVTPAELHGLLAGMISGGLSQQDQSWQPMLFDYTNDGMGWPSAALEQAQALFNVTSAQLTSDEMVLNLLLPNAEGEEAIFALADALSDWVNHYISGLGLAGAALNKASEEAKEALADLEEMARLGVDEDDDLQEQAELLEQVIEHVKACALLIHAEFGAKTSSSETPTIH
What are the official names of this protein?
UPF0149 protein VV2847.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: PRM9_YEAST
Sequence: MSPQYHFYFVSFRNLVLNEKCLRSKKQVMKSFNWYKTDRYFDPHNILQHHSRAIEKTRYKLGMQTSSESTDAKSDFLDEPSAYLIEKNVALPKDIFGSYLSYWIYEVTRHKAAVILLVLIVTSILLLVFFYNTEFCVAFEILLFSFCFPGTCMVVIAFSEPIGDREFKVKLLMEIITRKPAVKGKEWRTITYKMNQYLFDHGLWDTPYYFYRDEDCHRYFLSLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAAEIEQQFQKEYWRQEYPGVDEFF
What is the function of this protein?
May be involved in endoplasmic reticulum exit trafficking of proteins.
What are the official names of this protein?
Pheromone-regulated membrane protein 9, DUP240 protein PRM9.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
Protein: AROC_SHEB8
Sequence: MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTSIGLLIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGMRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGIEIYGFMSQLGPICAQTIDLDQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKISVIATGVPVGLGEPVFDRLDADIAHALMGINAVKGVEIGDGFGVVTQKGSEGRDLMSPQGFESNHAGGVLGGISSGQPIIAHIALKPTSSISVPGQSMTAQGEMAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQDVRSHTPVLGMR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GLGB_MYCTA
Sequence: MSRSEKLTGEHLAPEPAEMARLVAGTHHNPHGILGAHEYDDHTVIRAFRPHAVEVVALVGKDRFSLQHLDSGLFAVALPFVDLIDYRLQVTYEGCEPHTVADAYRFLPTLGEVDLHLFAEGRHERLWEVLGAHPRSFTTADGVVSGVSFAVWAPNAKGVSLIGEFNGWNGHEAPMRVLGPSGVWELFWPDFPCDGLYKFRVHGADGVVTDRADPFAFGTEVPPQTASRVTSSDYTWGDDDWMAGRALRNPVNEAMSTYEVHLGSWRPGLSYRQLARELTDYIVDQGFTHVELLPVAEHPFAGSWGYQVTSYYAPTSRFGTPDDFRALVDALHQAGIGVIVDWVPAHFPKDAWALGRFDGTPLYEHSDPKRGEQLDWGTYVFDFGRPEVRNFLVANALYWLQEFHIDGLRVDAVASMLYLDYSRPEGGWTPNVHGGRENLEAVQFLQEMNATAHKVAPGIVTIAEESTPWSGVTRPTNIGGLGFSMKWNMGWMHDTLDYVSRDPVYRSYHHHEMTFSMLYAFSENYVLPLSHDEVVHGKGTLWGRMPGNNHVKAAGLRSLLAYQWAHPGKQLLFMGQEFGQRAEWSEQRGLDWFQLDENGFSNGIQRLVRDINDIYRCHPALWSLDTTPEGYSWIDANDSANNVLSFMRYGSDGSVLACVFNFAGAEHRDYRLGLPRAGRWREVLNTDATIYHGSGIGNLGGVDATDDPWHGRPASAVLVLPPTSALWLTPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RNPH_SALAI
Sequence: MARPDGRLPDHLRPVTLTRGWSTHPEGSVLVEFGATRVLCTASVTEGVPRWRKGSGLGWVTAEYAMLPRATNTRSDRESVKGRVGGRTHEISRLIGRSLRASIDLKALGENSVVLDCDVLQADGGTRTAAITGAYVALYDAVTWLAARRSLAGRPENVMHRSVAAVSVGVVAGEPRLDLNYDEDATAEVDLNVVCTGTGDFVEVQGTGEAGVFSRGQLDALLDLAVAGCLDLAEAQRKALS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.