PharMolix/UniProtQA huggingface dataset:
Protein: 14333_ARATH
Sequence: MSTREENVYMAKLAEQAERYEEMVEFMEKVAKTVDVEELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKGNEDHVAIIKDYRGKIESELSKICDGILNVLEAHLIPSASPAESKVFYLKMKGDYHRYLAEFKAGAERKEAAESTLVAYKSASDIATAELAPTHPIRLGLALNFSVFYYEILNSPDRACSLAKQAFDDAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMTDEAGDEIKEASKPDGAE
What is the function of this protein?
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes (PubMed:7972511, PubMed:7870824, PubMed:16407442).  Involved in the regulation of nutrient metabolism (PubMed:22104211, PubMed:21094157).  Reciprocal negative transcription regulation of miR396 (PubMed:22751317).  Negative regulator of constitutive freezing tolerance and cold acclimation by controlling cold-induced gene expression partially through an ethylene (ET)-dependent pathway; prevents ethylene (ET) biosynthesis, probably by binding 1-aminocyclopropane-1-carboxylate synthases (ACS) to reduce their stability, thus contributing to establish adequate ET levels under both standard and low-temperature conditions (PubMed:25122152).
What are the official names of this protein?
14-3-3-like protein GF14 psi, General regulatory factor 3, Protein RARE COLD INDUCIBLE 1A.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from the cytosol to the nucleus when phosphorylated.
Protein: GUAA_SHEFN
Sequence: MSNIHDHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEAQIREFAPNGIILAGGPESVTADNSPRAPEYVFNAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIELQTTSALFKSIEDAVSAEGKPLLDVWMSHGDKVSAIPDGFVTVAKTATCPFAAMANEEKGFYGVQFHPEVTHTRQGQRMLEHFALDICGCKANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDSSVVAMLLHRAIGDKLTCVFVDNGLLRLNEAEQVLEMFGDHFGLNIVHVDAENRFLDAMAGEAEPEAKRKIIGRVFVEIFDEESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPADMKMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRSADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: WNK4_ORYSJ
Sequence: MEVFGDLDKVDDAECVEVDPTRRYIRYNEVLGRGAMKTVYKAFDEVEGIEVAWSQVEIDEVMQSPDNLERLYSEVHLLKSLKHENVMKFYNYWVDDQKKTINVITELFTSGSLRQYRQKHPRVDLKAIKNWARQVLRGLDYLHTHQPPIIHRDLKCDNIFVNGNHGEVKIGDLGLATVMLTPRAKSVIGTPEFMAPELYDENYDELVDIYSFGMCMLEMFTLEYPYSECTNAAQIFKKVSKGVKPAALAKITNIQAKQFIDKCLVPASERLSAKELLQDPFLCSDNSSVLVGTKFPSSLPKSVDVSLEALHMDVDTNESMCTSTCKRNDLGGPHRSVLEFTRTNKNTELKLTGEKLDDNSVSLVLRIADLCGHARNIHFLFYLDSDTAMSVAAEMVEQLELADCDVTFIADFIDLLIVNLVPGQQLMNDAVMSTSSESKMGESEHVITSQQHPSELTHDYVLVEGMMHSKEANASPSDYIDSLLNATNLGGPNSSEGSDISVQLDGSSKSLSEYGVDEYRTLECGAYKGTDKLGCRHPLSNGSSNFAIFQMDQASHHSELVIGASVSITENRDVLNGELGLIEAQYEQWFRELTRMREEALEGARKKWLPDK
What are the official names of this protein?
Probable serine/threonine-protein kinase WNK4, OsWNK4, Protein kinase with no lysine 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
Protein: BIOB_NITMU
Sequence: MSQSASGIVNIETSSGGAVDSFADKLSGISADFRRWDVRRVEALLDLPFSDLIHRAQLVHRQYHDPNGVQLSTLISVKTGGCPEDCGYCPQAARYHTNVENQDMLTVEDVIAAAAAAKAQGATRFCMGAAWRGPKERDMKSVVEMVRAVKALGLEACTTLGMLKPGQAEQLQEAGLDYYNHNLDTSPEFYGEIITTRDYEDRLDTLQKVRHAGINVCCGGIVGMGESRRARAGLIAQLANLDPYPESVPINHLVQVEGTPLHGTEALDPLEFVRTIAAARITMPKAMVRLSAGRREMPDAVQALCFLAGANSIFYGDKLLTTGNPEAERDKALFDRLGLHSI
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TBB_YEAST
Sequence: MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQEATVEDDEEVDENGDFGAPQNQDEPITENFE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:28013290).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with kinesin KIP3 at the plus ends of growing microtubules and along the microtubule lattice.
Protein: NUSB_TREDE
Sequence: MSVGRRRGRILAFQALVAWDVGGAVLDDLLNFSWQNEDSIKDPNGYLFPKMMVLGTIENITEIDKVIQENLDNWVIDRLNSVDKAILRLSVYSLIYQKDTPPPIVIDEAINLAKDFGTDDSYKFVNAVLDSIKNKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HSCA_PSEF5
Sequence: MALLQIAEPGQSPQPHQRRLAVGIDLGTTNSLVAALRSGLSEPLADAQGQVILPSAVRYHADRVEVGESARLAAPTDPLNTVLSVKRLMGRGLSDVKQLGEQLPYRFVEGESHMPFIETIQGPKSPVEVSAEVLKVLRQRAEAALGGELVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAVAYGLDQHAEGVVAIYDLGGGTFDISILRLTGGVFEVLATGGDTALGGDDFDHAIAGWIIEGAGLSADLDPGTQRSLLQAACAAKEALTGAASVEVVYGDWRATLTRDAFDALIEPMVARSLKACRRAVRDSNVELDEVQAVVMVGGSTRVPRVREAVAEMFGRQPLTEIDPDQVVAIGAAIQADTLAGNKREGGELLLLDVIPLSLGLETMGGLMEKVIPRNTTIPVARAQDFTTYKDGQTAMMVHVLQGERELISDCRSLARFELRGIPPMVAGAAKIRVTFQVDADGLLSVSARELGSGVEASIQVKPSYGLTDGEIAKMLKDSFQYAGDDKVARVLREQQVDAQRLIEAVQGALDADGERLLDAEERMVIELQMQELSELMRGTDGYAIEQQTKRLSQVTDAFAARRLDSTVKAALAGRNLNEIEE
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LEUD_ECO8A
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: Y695_BACCN
Sequence: MSKNIHDVAYGLQKAIADHTDFKTLKESYAKVQGDADSKQLFDTFRNMQLEIQQKMMQGQEITEEDNKKAQEVIDLIQQNEHIKKLMEAEQRLNVVIGDINKIIMKPLEELYSAYQA
What are the official names of this protein?
UPF0342 protein Bcer98_0695.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: HOX10_ORYSJ
Sequence: MAAAVAMRGSSSDGGGYDKVSGMDSGKYVRYTPEQVEALERVYADCPKPTSSRRQQLLRECPILANIEPKQIKVWFQNRRCRDKQRKESSRLQAVNRKLTAMNKLLMEENERLQKQVSQLVHENAHMRQQLQNTPLANDTSCESNVTTPQNPLRDASNPSGLLSIAEETLTEFLSKATGTAIDWVQMPGMKPGPDSVGIVAISHGCRGVAARACGLVNLEPTKVVEILKDRPSWFRDCRNLEVFTMIPAGNGGTVELVYTQLYAPTTLVPARDFWTLRYTTTMEDGSLVVCERSLSGSGGGPSAASAQQYVRAEMLPSGYLVRPCEGGGSIVHIVDHLDLEAWSVPEVLRPLYESSRVVAQKMTTAALRHIRQIAQETSGEVVYALGRQPAVLRTFSQRLSRGFNDAISGFNDDGWSIMGGDGVEDVVIACNSTKKIRSNSNAGIAFGAPGGIICAKASMLLQSVPPAVLVRFLREHRSEWADYNIDAYLASTLKTSACSLTGLRPMRFSGSQIIIPLAHTVENEEILEVVRLEGQPLTHDEALLSRDIHLLQLCTGIDEKSVGSSFQLVFAPIDDFPDETPLISSGFRVIPLDMKTDGASSGRTLDLASSLEVGSATAQASGDASADDCNLRSVLTIAFQFPYELHLQDSVAAMARQYVRSIVSAVQRVSMAISPSQTGLNAGQRIISGFPEAATLARWVCQSYHYHLGVELLSQSDGDAEQLLKMLWHYQDAILCCSFKEKPVFTFANKAGLDMLETSLVALQDLTLDRIFDEPGKEALFSNIPKLMEQGHVYLPSGVCMSGMGRHVSFDQAVAWKVLAEDSNVHCLAFCFVNWSFV
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX10, HD-ZIP protein HOX10, Homeodomain transcription factor HOX10, OsHB1, OsHox10.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class III subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MK10_RAT
Sequence: MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSSVVKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death.  Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.  In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3.  In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity.  Plays regulatory roles in the signaling pathways during neuronal apoptosis.  Phosphorylates the neuronal microtubule regulator STMN2.  Acts in the regulation of the amyloid-beta precursor protein/APP signaling during neuronal differentiation by phosphorylating APP.  Participates also in neurite growth in spiral ganglion neurons.  Phosphorylates the CLOCK-BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (By similarity).  Phosphorylates JUND and this phosphorylation is inhibited in the presence of MEN1 (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 10, MAP kinase 10, MAPK 10, SAPK-beta, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, p54-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Nucleus. Mitochondrion. Note=Palmitoylation regulates MAPK10 trafficking to cytoskeleton. Recruited to the mitochondria in the presence of SARM1.
Protein: PETD_SACHY
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPTGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYS_SHESR
Sequence: MLDPKFLRNELAVTAERLATRGFILDVAHLTQLEEKRKSLQVATEELQASRNAISKSIGQAKARGEDVDAIMAQVGDLGAQLDAKKVELAAVLEEVNAIAMSMPNLPDESAPIGADETENVEIRRWGTPRSFDFPVKDHIDLGEGLNGLDFKSAVKITGSRFIVMKGQIARLNRALGQFMLDLHTTEHGYTEAYVPLLVNEASLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDSIVDEDELPIKLTAHTACFRSEAGSYGKDTRGLIRQHQFDKVELVQLVKPEDSMAALEALTGHAETVLQRLGLPYRTVILCTGDMGFGSSKTYDIEVWLPGQNTYREISSCSNMKDFQARRMQARYRVKADNKPALLHTLNGSGLAVGRTLVAILENYQNADGSVTIPEALRPYMGGLTQIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CHLCV
Sequence: MKQQLLLLEDVDGLGRSGDIVTARPGYVRNYLMPQKKAVIAGAGTLRLQAKLKEERLLRAAEDRAESEKLAEALRDVILEFQVRVDPDNNMYGSVTISDIIDEAAKKNIILTRKNFPHSHYAIKNLGKKSVPLKLKEDVTATLFVEVSSESSYVAVLNQQPTQEEPAAEESN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DING_ECOL6
Sequence: MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase.
What are the official names of this protein?
ATP-dependent DNA helicase DinG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
Protein: GAG_HV1ET
Sequence: MGARASILRGEKLDAWEKIKLRPGGKKHYMLKHLVWANRELEKFALNPDLLDTSAGCKQIIKQLQPALQTGTEELKSLFNTVATLYCVHQKIEIKDTKEALDKIEEEQNESQQKTQQAGAADRGKDSQNYPIVQNMQGQMVHQPISARTLNAWVKVVEEKAFSPEVIPMFTALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPVAPGQMRDPRGSDIAGTTSTLQEQIAWMTGNPPVPVGDIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTDTLLVQNANPDCKTILRALGPGASLEEMMTACQGVGGPAHKARVLAEAMSQVNNTTIMMQKSNFKGPKRAIKCFNCGKEGHLARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGRLWPSNKGRPGNFLQSRPEPTAPPESLRPEPTAPPPESFRFEEATPSPKQELKDREALTSLKSLFGNDHLLQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: HUS1B_HUMAN
Sequence: MKFRAKITGKGCLELFIHVSGTVARLAKVCVLRVRPDSLCFGPAGSGGLHEARLWCEVRQGAFQQFRMEGVSEDLDEIHLELTAEHLSRAARSAAGASSLKLQLTHKRRPSLTVAVELVSSLGRARSVVHDLPVRVLPRRVWRDCLPPSLRASDASIRLPRWRTLRSIVERMANVGSHVLVEANLSGRMTLSIETEVVSIQSYFKNLGNPPQSAVGVPENRDLESMVQVRVDNRKLLQFLEGQQIHPTTALCNIWDNTLLQLVLVQEDVSLQYFIPAL
What are the official names of this protein?
Checkpoint protein HUS1B, hHUS1B.
What is the protein family that this protein belongs to?
Belongs to the HUS1 family.
Protein: GCH4_METCA
Sequence: MEEEGLAIDDVQGRADLRRIDIDRVGIKGIRHPVRVRDRSLGEQHTVARFDMAVSLPHHFKGTHMSRFVEIINGHDREIDIASFEAMLAEMMQRLNAEAGRIEMRFPYFLEKRAPVTGVRSLMDYEVALIGEVSVATTTTWLGVTVPVTSLCPCSKAISERGAHNQRSHVTTAVRMRDFVWIEELIEWVEAEASSPIYGLLKRPDEKYVTEYAYDHPRFVEDLVRGVAARLDTEPRIAAYAVEVENFESIHNHSAYALIERDKRTADA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: CCMA_MARMM
Sequence: MTEKFPDLPDLQPETLRVSGLSLSRGDITLVRDFSLDLAPGQAMLMSGPNGTGKTTLLRAVAGFVRPDAGRVVFGEGPKADSASELVAWLGHADGLKPVETPRQSLRFWAKMNDQGRDPILPLMRAMAIESLIDRPASRLSRGQQRRCALVRVALANRPIWLLDEPAGPLDGGGRARLAALVDWHRSRGGSVIAATHQSLDWPDAKRIDLGAHR
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVC_METST
Sequence: MKVLYDDDVNTNVLENKTIAVIGYGSQGRGQSLNMHDSGLNVIVGLREGGKSWKKAQEDGLTVKTIEDASKEADIIHILIPDEIQKTVYENQIQQYVEPGNTISFSHGYNIHFNRIRVPEDVNVTMIAPKAPGSKVRQTYQEGFGTPGLIAIEQDATGDAYDIAIEMAKAVGLTRAGVIETTYREETETDLFGEQAVLCGGLTGLIQAGFETLVEAGYKPEMAYFETCHEMKLIVDLIYEKGFGNMWHDVSNTAEFGGLTRRDRVITEESKENMKKILREIQDGTFATEFAVDADTSYPKLLTQRRLEGEKQIEKVGKNLRIACGLQKEE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: XYLT2_PANTR
Sequence: MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEAGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSTGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGSLMPKAVPRHCQLTGKMSPGIQWDESQAQQPMDGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSNYLHREVVELAQGYDNVRVTPWRMVTIWGGASLLTMYLRSMRDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLENSLACETLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENTYDAADGPSGLSDVMLTAYTAFARLSLHHAATAAPPMGTPLCRFEPRGLPSSVHLYFYDDHFQGYLVTQAAQPSAQGPAEMLEMWLMPQGSLKLLGRSDQASRLQSLEVGTDWDPKERLFRNFGGLLGPLDEPVAVQRWARGPNLTATVVWIDPTYVVATSYDITVDTETEVTQYKPPLSRPLRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQGLSSILNLPQPELAEEAAQRHTQLTGPALEAWTDRELSSFWSVAGLCAIGPSPCPSLEPCRLTSWSSLSPDPKSELGPVKADGRLR
What is the function of this protein?
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity).  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
What are the official names of this protein?
Xylosyltransferase 2, Peptide O-xylosyltransferase 2, Xylosyltransferase II.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Protein: RL7A_ANOGA
Sequence: MVTKKPVKKKVVPKQKVAPAPLAKPKKVEVKKVVNPLFEKRVKNYGIGQNVQPKRDLSRFVKWPKYIRIQRHRAILQKRLKIPPPINQFTQTLDKPTAQQVMKMLEKYRPENPIARVQRLKAKAEAKAAGKEEPPSKRANQLRQGINSVVKMVEQKKAQLVIIAHDVDPIELVVYLPALCRKMGVPYCIIKGKARLGTLVYRKTCTCVALTQVENADKPNLAKLVETIKTNFNDRFDDIRRHWGGGLLGPKSMARLAKLEKAKKREMLQKN
What are the official names of this protein?
60S ribosomal protein L7a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: MROH5_HUMAN
Sequence: MDRQCSERPYSCTPTGRVSSAVSQNSRISPPVSTSMKDSSCMKVHQDSARRDRWSHPTTILLHKSQSSQATLMLQEHRMFMGEAYSAATGFKMLQDMNSADPFHLKYIIKKIKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNGATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHILPWVDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAMHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPKQ
What are the official names of this protein?
Maestro heat-like repeat family member 5.
Protein: SYP_CITK8
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDVIFSDSSDYAANIEFAEAVAPKAPRAAASQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSYPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRALVKAGPGSLGPVNMPVPVVIDRTVAVMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYGELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGEIVDFLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.