PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_BRUA2
Sequence: MPTGKLRQKPPYAAIMTNSPVTPSTETQQPKRDALYARFLPQEADAPPVEWLIAEGLTDYEEALAFMEARVQATREGTASELVWLVEHPPLYTAGTSANAEDLLTPDRFPVFNTGRGGEYTYHGPGQRVAYVMLDLKRRREDVRAFVASLEQWIIETLAAFNIKGERREDRVGVWVVRPEKPRLADGSMCEDKIAAIGIRLRRWVSFHGIAINVEPDLSHYGGIVPCGISEHGVTSLVDLGLPVTMGDVDVALGKAFESVFGPRQTK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_ROTHS
Sequence: MKVLALRHSVAQVYADTQVYTHDDSKDEYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAIEIQKMDELFTLIRCNFTYDYIDDVVYLHDYSYYTNNEIRTDQHWITKTNIEDYLLPGWKLTYVGYNGSDTRGHYNFSFRCQNAATDDDAIIEYIYSDELDFQSFILKKIKERMTTSLPIARLSNRVFRDKLFKTLSVNHDKVVNIGPRNESMFTFLDHPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDIYHEKPIVYMIGSAPSYWIYDVKQYSDLKFETWDPLDTPYSNLHHKELFYINDVQRLKDNSILYIDIRTDRGTMDWKEWRKMVERQTTDNLHIAYKYLSTGKAKICCVKMTAMDLELPISAKLLHHPTTEIRSEFYLMMDIWDSKNIKRFIPKGVLYSYINNTITENVFIQQPFKLKTLKNEYIIALYALSNDLNNREDVVKLINNQKKALITVRINNTFKDEPKVGFKNIYDWTFLPTDFETNGSIITSYDGCLGIFGLSISLASKPTGNNHLFILSGTDKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTGKASIEGGKYYEHAPIELIYACRSAREFAKLQDDVTVLRYSNEIENYINKVYSITYADDPNYFIGVKFKNIPYKYNVKVPHLTFGVLNISEQMLPDVIVILKKFKNELFGMEITTSYTYMLSDEVYVANISGVLSTYFKIYNAFYKEQITFGQSRMFIPHVTLSFSNEKTVRIDNTKLYIDSIYLRKIKGDTVFDMTG
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: IHFB_BURMA
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALSKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKHVPHFKPGKELRERVDGRAGEPLKNDEPEDAQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SP5AF_BACSU
Sequence: MPDHKEEKIRVYRNPAKNEEYFKNRVGMGTSYDVGVRKLTILDKEIQLYYLNGLCDTAYIIHLMRELVAINNRKEDPDELVDIVENRLLNAQVEKVKTLDETTDQVLSGLVAVIVEGAGFAFIIDVRSYPGRNPEEPDTEKVVRGARDGFVENIVVNTALLRRRIRDERLRVKMTKVGERSKTDLSICYIEDIADPDLVEIVEKEIASIDVDGLTMADKTVEEFIVNQSYNPFPLVRYTERPDVAANHVLEGHVIIIVDTSPSVIITPTTLFHHVQHAEEYRQAPSVGTFLRWVRFFGILASTLFLPIWFLFVLQPDLLPDNMKFIGLNKDTHIPIILQIFLADLGIEFLRMAAIHTPTALSTAMGLIAAVLIGQIAIEVGLFSPEVILYVSLAAIGTFTTPSYELSLANKMSRLVLMILVALFHIKGLVIGFTVLIIAMASIKSLQTPYLWPLIPFNGKALWQVLVRTAKPGAKVRPSIVHPKNRLRQPTNS
What are the official names of this protein?
Stage V sporulation protein AF.
What is the protein family that this protein belongs to?
Belongs to the GerABKA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_MABVO
Sequence: MDLHSLLELGTKPTAPHVRNKKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPIAKYLRDAGYEFDVIKNADATRFLDVIPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKLQRRHEHQEIQAIAEDDEERKILEQFHLQKTEITHSQTLAVLSQKREKLARLAAEIENNIVEDQGFKQSQNRVSQSFLNDPTPVEVTVQARPVNRPTALPPPVDDKIEHESTEDSSSSSSFVDLNDPFALLNEDEDTLDDSVMIPSTTSREFQGIPESPGQSQDLDNSQGKQEDESTNPIKKQFLRYQELPPVQEDDESEYTTDSQESIDQPGSDNEQGVDLPPPPLYTQEKRQDPIQHPAASSQDPFGSIGDVNGDILEPIRSPSSPSAPQEDTRAREAYELSPDFTNYEDNQQNWPQRVVTKKGRTFLYPNDLLQTSPPESLVTALVEEYQNPVSAKELQADWPDMSFDERRHVAMNL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication.  During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the filoviruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RS20_ACIB3
Sequence: MANSAQAKKRARQNVKARKHNASLRSMVRTYIKRTLSAIAGGDYAVATEAYKKAVPVIDRMADKGIIHKNKAARHKSRLNAQVKALAN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: EFTU_GRAFK
Sequence: MAKEKYDRSKPHLNIGTIGHVDHGKTTLTAAITKVMADAGYSEASAFDQIDNAPEEKERGITINSSHVEYSTEKRHYAHVDCPGHADYVKNMVTGAAQMDGAILVVAATDGPMPQTREHILLGRQVGIPRIVVFLNKVDLVDDEELLELVEMEVRDLLSFYEYDGDNGPVISGSALGALEGDEKWSKTVLELMEAVDTWIELPERDVDKAFLMPIEDVFSITGRGTVATGRIETGVANTGDPIEIIGMGAGKLTSTITGVEMFRKILDRGEAGDNVGILLRGIEKSQISRGMVITKPGSVTPHAKFKAEVYILKKEEGGRHTPFHNNYRPQFYVRTTDVTGTISLPDGVEMVMPGDNLTITVELIQAIAMNQGLRFAIREGGRTVGAGQVTEILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSA_PSEA6
Sequence: MSQQIYPVPAHAKEHSHLTPADYARMYAESVEQPEVFWAEQAKSLDWVKTPTKIKNTSFDAHHVSIKWFEDGELNVAYNCIDRHLAKRGHVTAFIWEGDDPHSHDIITYHRLHDEVAKIANGLRKLGVGKGDRVAIYMPMIPQAVYAMLACARIGAVHTVIFGGFSPNAIADRVNNCQAKVLITADEGLRAGKHIPLKDNVDTALAEHDCPSMEQVIVFKHTGSHVSWGKDDVWWHDLTDGCSTDCPPEVMNAEDPLFILYTSGSTGQPKGVVHTTGGYLLWASITHKYVFDYKPGDIYWCAADVGWVTGHSYIVYGPLANGATSVMFEGVPTYPDVRRIGQIVDKHKVNILYTAPTAIRALMAHGDFPTEGISGESLRLLGSVGEPINPEAWHWYYTTVGQSRCPIVDTWWQTETGAAMLTPLPSVTAMKPGAASHPFFGVQPALVDGQGNELSGATEGNLIITDSWPGQARTVYGDHERFVQTYFTTYPGTYCTGDGARRDEDDYFWITGRVDDVLNVSGHRLGTAEIESALVSHNAVAEAAVVGYPHDLKGQGIYVYLMPNEGVEITDELTKEVSNWVRKELSPIATPDLIQWSSGLPKTRSGKIMRRILRKIAANEYEQLGDTSTLADPSVVDTLIEQRLNR
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DNLI_CENSY
Sequence: MQFSVLAGSLEKMESTAKRLELTGILEELLRETPHEVIAQIVYLIQGKLRPEFEGIELGVAEKLAVRAVSKSSGMPAARIEAAYRRDGDLGRAASSILEQKTQTTFLAEEITVERVYDTLMRIARLEGARSQDMKMRHISSLLNDASPRDACYILKLILGTLRLGIAENTVMDALAAAFTGSKSNRPELERAYNVSSDLGRVAEAVSSGGLEAVRGFAVAVFSPIRPMLADRVRSESEALEKMGAGLAAEYKLDGERVQVHLSGGRVELFSRSLENITAYYPDIVERIPGRLRAREAVLEAEAVAVNEETGEFLPFQELMHRRRKYDIDKAVMRYPITVNFFDILYLDGRDCLGISYSERRALLEGVVDEDSFARCVPVSTIPDESALEDSLENSINAGCEGLMLKLPDAPYRAGSRGGYWLKLKREYRNELGDSLDLVIIGAFFGKGRRTGRYGTLLLATYDDSRDTFPSICKVGTGFTDEDLDQLYQLLSPRVTLKRNPRIDSGMEADVWFDPEVVMEVVASEITLSPVHKTALDSVRKGAGLALRFPKFTGKLRTEKTAEDASTDQEVIALYKSQKKVVPDGQPGV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: MURB_STAAB
Sequence: MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_DICNV
Sequence: MARSLKKGFFIDLHLAHKVDVAVETKSKKPIKTWSRRSMIIPDMIGLTIAIHNGKQHVPVLITEDMIGHKLGEFAPTRNYRGHTAADKKGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: URE1_SULTO
Sequence: MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNVREEEVMDLIITNVVILDPLLGVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEIISGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGTGPAEGTKATTVTPGSWNIKIIAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYDVQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNPTKPYTIHTYEEHLEMLMAVHHLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSDSQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLAKITINPAITHGISDYVGTLAPGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSVSFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVPKVPPSKSLPLTQLYFIY
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH_STAAS
Sequence: MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
What are the official names of this protein?
Alcohol dehydrogenase, ADH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ARC_MYCSK
Sequence: MSESQRHEAREDGFTTPHESGLSSEDAAELEELRREAAALREQLENAVGPQSGLRSARDVHQLEARIDSLAARNAKLMDTLKEARQQLLALREEVDRLGQPPSGYGVLLASHEDDTVDVFTSGRKMRLTCSPNIDVKALKQGQTVRLNEALTVVEAGTFEAVGEISTLREILSDGHRALVVGHADEERIVWLAEPLVSVEHLPDNEVAGPELDDDRPRRLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYSDIGGLTRQIEQIRDAVELPFLHKDLYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIFSKYLTEELPVNEDDLAEFGGDRSLTIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKYAIKSVLETGQKGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSANRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: UBIG_VIBCM
Sequence: MASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGLFGKRVLDVGCGGGILAESMAREGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAHAEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHVFFSTLNRNVKSYLFAIVGAEKLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIVHTRLF
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: ING4_MOUSE
Sequence: MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKAAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK
What is the function of this protein?
Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4.  Through chromatin acetylation it may function in DNA replication.  May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation.  Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA.  May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC.  Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (By similarity).  Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (PubMed:11888890).
What are the official names of this protein?
Inhibitor of growth protein 4, p29ING4.
What is the protein family that this protein belongs to?
Belongs to the ING family.
Protein: NUOI_SHIF8
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YIDD_BACAN
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGAFKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVNS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RRF_XYLFT
Sequence: MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMSKDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDIQKLTDKAIKSVDEVVKSKEQELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS6B_SCHPO
Sequence: MNSTEEIDLYNRWKALERQLEMLDLQEGFIKEDCKSLKRELIRAQEEVKRIQSVPLVIGQFLEAIDQNTAIVGSTTGSNYVVRILSTLDRELLKPSASVALQRHSNALVDILPPEADSSISMLRPDERPDVSYADVGGLDVQKQEVREAVELPLTQGDLYRQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTAANFIRVVGSEFVQKYLGEGPRMVRDVFRMARENAPAIIFIDEIDAIATKRFDAQTGADREVQRILIELLTQMDGFDQGANVKVIMATNRADTLDPALLRPGRLDRKIEFPSYRDRRQRRLVFQTITAKMLLSPEVDLDTFIMRPDASSGAQIAAIMQDAGLLAVRKSRGVILQSDIEEAYARAVKPTDMEQFAFYK
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 6B homolog.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DPO4_FRAP2
Sequence: MSKTRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAMPTAIAMQKCPNLILLNTDFAKYKATSAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKNSATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINKPNGLYVITPEQVDSFVKDLPVKKLFGVGKVSQEKLKNMNVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPVRIRKSVSVENTYLEDLKTLEACLEKLPNLYNKLTSRMTEEHYKSIIGIVVKFTDTKFNKTSLTRVAKTLDKKVLKNLIIELHQKQNYHIRLIGIGIKLGEIDDRQLSLVF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_RHILO
Sequence: MSKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHVNQWLKKAVLLSFRLNPMEIIKGGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRRSAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVVVAGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_PSEMY
Sequence: MAEIDARLREEVHLLGELLGQTIRTQLGDDFLDKIERIRKGAKAGRRGSAAGAEQLTSTLGDLGDDELLPVARAFNQFLNLANIAEQQHRVRRRRPDEPEPFELRVLDELLERLLAAGQKPDELARQLGRLDIELVLTAHPTEVARRTLIQKYDAIAAQLTALDHSDLLPAERERIAQRLQRLIAEAWHTEEIRRSRPSPVDEAKWGFAVIEHSLWQAVPQFLRRADRSLQAATGLRLPLEAAPIRFASWMGGDRDGNPNVTARVTREVLLLARWMAADLYLRDVDQLAAELSMQQASAELRAQVGDSAEPYRALLKQLRERLRETRSWAQQALTADIAPGAAVLQDNHDLLAPLQLCYQSLHACGMGVIADGPLLDCLRRAATFGLFLVRLDVRQDSTRHAAALSEITDYLGLGRYAEWDEEQRLAFLQRELDSRRPLLPSDYRPSADTAEVLATCREVAAAPAAALGSYVISMAGAASDVLAVQLLLKEAGLRRPMRVVPLFETLADLDNAGPVIDRLLGLPGYRVRLHGPQEVMIGYSDSAKDAGTTAAAWAQYRAQEELVRLCGEHQVELLLFHGRGGTVGRGGGPAHAAILSQPPGSVAGRFRTTEQGEMIRFKFGLPDIAEQNLNLYLAAVLEATLLPPPAPEPSWRAMMDRLADVGVKAYRGVVREHPQFVAYFRQATPEQELGRLPLGSRPAKRREGGVESLRAIPWIFAWTQTRLMLPAWLGWEQALGQALAGGEGELLKNMREQWPFFRTRIDMLEMVLAKADASIAALYDQRLVEPALQPLGAQLRDLLSQACAAVLELTGQSRLLAHSPETLESISVRNTYLDPLHLLQAELLARCRLRQQAPESPLEQALLVSVAGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: COR2A_HUMAN
Sequence: MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTENELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL
What are the official names of this protein?
Coronin-2A, IR10, WD repeat-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
Protein: PUR4_YEAST
Sequence: MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHYVNGIAQNLSEQDTKLLEVLLTYDSALDIANDPLARQLNDAVANNLPSSALGEDTYLIRVVPRSGTISPWSSKATNIAHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSIFTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTDVELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNAAVLDSENDAFFFAPNSTTKEWTSTKERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDEGATGRGSKTKCGLSGFSVSDLLIPGNEQPWELNIGKPYHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLGGQSMLIGLGGGAASSVASGEGSADLDFASVQRGNPEMERRCQQVIDACVALGNNNPIQSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDLSIFEEICKRERAPFAVVGHATAEQKLIVEDPLLKTTPIDLEMPILFGKPPKMSRETITEALNLPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVADVGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKLSANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSLNITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPTVYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGDLESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTTNDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDMKIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPGCENWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHPERVCRLEANSWYPEGKYEEWGGYGPWIRLFRSARRWVG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT, Formylglycinamide ribotide amidotransferase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.