PharMolix/UniProtQA huggingface dataset:
Protein: O12D2_HUMAN
Sequence: MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKPLRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVILFYAPVLFTYIHPALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 12D2, Hs6M1-20, Olfactory receptor OR6-28.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_ALBFT
Sequence: MKTAQEIRVGNVIMYGKDPMVVLRTEYSRGGRNSSTVRMKLKSLIANFNTEVVYKADDKLEQVILDKKECTYSYFAEPMYICMDTEYNQYEVEAENMGDSLNYLEDGMELEVVFYNEKAISVEMPTNVVREITWTEPAVKGDTSGKVLKPAKISTGFDVGVPIFVAQGDKVEIDTRTGEYRKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE13_LITPE
Sequence: QPWLPFV
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
What are the official names of this protein?
Peroniin-1.3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Peroniin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PER_DROPV
Sequence: SSTETPPSYNQLNYNENLLRFFNSKPVTAPVELDPPKVESSYVSSARGEDARSTLSPVQGFEGSGGSGSSGNFTTGSNLHMSSVTNTSNAGTGTSGTGNSGDGGGGGGANGTGSGAAPPVTLTESLLNKHNDEMEKFMLKKHRESRGRSGEKNKKSANEAMKMLEYSGPGPGHGHGIKRGGSHSWEGEANKPKQQLTLNTSGGGGGVGVGGGMPLFLDITHASSSSQNKGLAGVGVGGAGGVVGGGGSGTGLGGNGNVGSGNGNNNQPSTNQYTQSRLPCTQNINLWPPFSVGITTPTSVLSSHTAVPPSSFSPQHSLFPTFYYIPASIAASSPSSTNTNPNRPHKHAHVHNSSEKPSTSQAAAATMPLQYMTGVMYPHPSLFYTHPAAAAATAMV
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: YE7A_SCHPO
Sequence: MNVYVQRDDVGLGQIHRFRIFVQSGGNLHSATSSTTVPPTVNLNSVTKKESGSIEDRAGSGGMTISSGENISKQISENNSSTNPKHANSESSPLLSSDFSSSSKDYHKVGAFTDNTNAINIPEQTRGVSHTSSSPSVGTSFSSINLREVKNPLAGSDSTAPFINSTNSVLWIRVRNREARFRQAAYLQGPFTLCVSVWNDQFFDEKNSLLNFDPQVQPSTSFWVCVPYSCFSNQQPIYIEIASQAIFKDRSINFELAISQSQHSIRAMSAADIDTLHAFPALHVEHQTPENLWRLPYSSFHSKNSHLVVLTHGMHSNVGADMEYLKEKLIESSKSVKELVVVRGFTGNYCQTEKGVRWLGKRLGEWLLDITGWGSASFPRYSHISVVAHSLGGLVQTYAVGYVHAKTHGAFFQAIHPVFFVTLATPWLGVAGEHPSYIGKALSYGIIGKTGQDLSLTPLNHSIESRPFLVLMSDPSTPFFQAVSFFEKRILFANTTNDYIVPFGTSAMEVSSLGKVEEAEGSDKVMPTHMENGISPTLKENEQTVQSVGDNAKKIHASSEESGSSFSKALKSFVGLFSYSASKTTDTEIPLVKNEDENARKPTEPNCLGSDELDVSNSSNQFFCSAPKLDPTSTFSGVAQRVVNTFTNLFIPAVPTDSYFFKYHLHKVVVSDNVHDPAASFSTFDGITELNNMNNGFLSNEITIAKNWHRLAWRKVAVRLDGDAHNTMIVRRRFPNAYGWTVIKHLTEILFEQNTSTAYMNPISFDETTTAAWLSEIYEDNSISV
What are the official names of this protein?
Putative lipase C4A8.10.
What is the protein family that this protein belongs to?
Belongs to the putative lipase ROG1 family.
Protein: SYRM_XENLA
Sequence: MAWHFRRVIAEQVSRVLGLPSESCSRVAQCIQTVPVHRKHESPDFQLFMTSLSEGGPNGTFSNQEERAEQLAGKLVCDSVISDIGTTRGSVTFKINRDLLTRNVLQQISKDGSLYGLNTELFSELSRRKTIVEYSSPNIAKKFHVGHLRSTIIGNFIANLKQAVGNEVVRINYLGDWGLQFGLLGAGFSSFGSKEKLLANPLQHLFEVYVKVNTAAEKDNGIKLSAQEFLRRLEGGDPHALSLWMHFRDISIQEYAKIYKRLGAHFDDYSGESFYKEKSQEVLKQLESKGLLLKTDKGTVIDLSEEGNLSSYSTVMRSDGTSLYITRDMAAAVDRMERYNFDEMIYVTDKSQKNHFQQLFKILKIMGKDQADRCQHVPFGLVQGMKTRRGEVVFLEDVLDEARSRMLQNMAASETSKQLDDPSDTAEKIGIAALIVQDFKGQLVSDYHFDWDQALQSTGDTGVFLQYTHARLHSLQALRCPRDTEDFEIASLREPCVIATLQHLLRYDEVIYKCLEDLQPRYLVTYLLSLGHLANVAHRTLQVKGSSSEAAHARLLFFKNVQMVLGNGMKLLGITPVNNM
What are the official names of this protein?
Probable arginine--tRNA ligase, mitochondrial, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TPIS_BOVIN
Sequence: MAPSRKFFVGGNWKMNGRKNNLGELINTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVANGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSARIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R51A1_CHICK
Sequence: MARMVRRNRKIVNYSEFGDFEDGDEDFACIAAPLTKKSRTQPKEPKKENKKKQKTQKEFTSSQKQSPIGRTSLDDSFCERDLNVTLALSIKEKSANILEVQNSKEQGQVLDDDIPRNGCRQWTAASKAFSHQKLLTIDSCDREHVTDSEPVTIPDEESEEDSDYREGNDEDCAMEKMKINGMKKKIKRQTRKEKKTPKSENNTTVMELKSEQTQKMMSTSSEPVGRPLYTSSPVTNKKPKWVPPGRACAVSFL
What is the function of this protein?
Structure-specific DNA-binding protein involved in DNA repair by promoting RAD51-mediated homologous recombination (By similarity).  Acts by stimulating D-Loop formation by RAD51: specifically enhances joint molecule formation through its structure-specific DNA interaction and its interaction with RAD51 (By similarity).  Binds single-stranded DNA (ssDNA), double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures: has a strong preference for branched-DNA structures that are obligatory intermediates during joint molecule formation (By similarity).  Involved in mitotic recombination-dependent replication fork processing (PubMed:25288561).  Also involved in meiosis by promoting DMC1-mediated homologous meiotic recombination (By similarity).
What are the official names of this protein?
RAD51-associated protein 1, GgRAD51AP1.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci. Colocalizes with DMC1 on meiotic chromatin.
Protein: RX24L_ARATH
Sequence: MELVSFGVEKLWDRLSQEYDQFKGVEDQVTELKSNLNLLKSFLKDADAKKHISEMVRHCVEEIKDIVYDTEDIIETFILKEKVEMKRGIMKRIKRFASTIMDRRELASDIGGISKRISKVIQDMQSFGVQQIITDGSRSSHPLQERQREMRHTFSRDSENDFVGMEANVKKLVGYLVEKDDYQIVSLTGMGGLGKTTLARQVFNHDVVKDRFDGFAWVSVSQEFTRISVWQTILQNLTSKERKDEIQNMKEADLHDDLFRLLESSKTLIVLDDIWKEEDWDLIKPIFPPKKGWKVLLTSRTESIAMRGDTTYISFKPKCLSIPDSWTLFQSIAMPRKDTSEFKVDEEMENMGKKMIKHCGGLSLAVKVLGGLLAAKYTLHDWKRLSENIGSHIVERTSGNNSSIDHVLSVSFEELPNYLKHCFLYLAHFPEDHEIDVEKLHYYWAAEGISERRRYDGETIRDTGDSYIEELVRRNMVISERDVMTSRFETCRLHDMMREICLFKAKEENFLQIVSNHSPTSNPQTLGASRRFVLHNPTTLHVERYKNNPKLRSLVVVYDDIGNRRWMLSGSIFTRVKLLRVLDLVQAKFKGGKLPSDIGKLIHLRYLSLKDAKVSHLPSSLRNLVLLIYLDIRTDFTDIFVPNVFMGMRELRYLELPRFMHEKTKLELSNLEKLEALENFSTKSSSLEDLRGMVRLRTLVIILSEGTSLQTLSASVCGLRHLENFKIMENAGVNRMGEERMVLDFTYLKKLTLSIEMPRLPKIQHLPSHLTVLDLSYCCLEEDPMPILEKLLELKDLSLDYLSFSGRKMVCSAGGFPQLRKLALDEQEEWEEWIVEEGSMSRLHTLSIWSSTLKELPDGLRFIYSLKNLIMGKSWMERLSERGEEFYKVQNIPFIKFSS
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein RXW24L.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: GATE_HALSA
Sequence: MTEFDYDELGLVAGLEIHQQLDTATKLFCACPTTRREPAEADRTFTRYLHPTRSELGEIDEAALEESRVEREFEYLAYDTTCLVEEDDEPPHRLDEDALAAALEIGHLLGMDAVDRAHVMRKVVIDGSNTGGFQRSTMVAEGGAIDTSEGPVGIEDLMLEEESAQRIEDREDGVLYSLDRLGIPLVEIGTKPDISSPAQAREAAERIGMLLRSTGKVKRGLGTIRQDVNVSIADGARVEMKGVQSLDDIDDLVREEVRRQVELLDIVDELDARDAAVGKPRDVTDVFADTESGVIRGALDDGGEVHAVPLHGFDGLVGRELQADRRLGTEFSDHATRHGAGGIFHTDELPAYGVTAAEVAALRDAVGAGEDDAVAIVADDPETAAQSIQAVAERAETAMAGVPEETRGANDDGTSKYLRPLPGAARMYPETDVPPVDPDPSAVETPELLTEKVERYQADFDLDAGLAEQVAYGRRWQLFEQQVEAGVDATLAAQTLESTVTELRRDDVPVGRLTDAHFRGVLGLVADGDLAQEGVPELLAALAEQPGSDPAVLAEELGLGSAAEDEVREAVVGVVERNSDQVAAEGMGAFSALMGECMGALRGKADGDLVSEVLREEIQQRS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: METK2_ARATH
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATIDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKIGARLTEVRKNGTCRWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKETFDFRPGMMTINLDLKRGGNGRFQKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2G_METVS
Sequence: MVASNQSEVNIGMVGHVDHGKTSLTRKLTGVWTDTHSEELKRGISIRLGYADCEIKKCESCNEPECYTVDKKCDCCSGKVETLRKISFVDAPGHETLMATMLSGASLMDGAILVIAASEECPQPQTKEHLMALDALGVKNILIVQNKIDLVTEEQAVENYEQIQKFTKGTVAEKAPIIPVSAHHGANLDVLLKAIQEFIPTPKRDETVSPRLYVARSFDVNKPGSEIKDLKGGVIGGSIIQGILKVGDEIEIRPGSKVVEGNKTKWVPIITKIISLGAGSKKLKTALPGGLIGVGTELDPNLTKSDALSGSLAGIPGTLPETLEKITIRPQLLERVVGSQDELLIEPLKTNEVLMLNVGTSTTVGVTVSAKAEKVEIKLKLPVCADSGDRVAISRKIGSRWRLIGYGIIL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: JPH3_HUMAN
Sequence: MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSRGVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRLLELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGFGVQRLRSKAQNKENFRPASSAEPAVQKLASLRLGGAEPRLLRWDLTFSPPQKSLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI
What is the function of this protein?
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells.  Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.  JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
What are the official names of this protein?
Junctophilin-3, JP-3, Junctophilin type 3, Trinucleotide repeat-containing gene 22 protein.
What is the protein family that this protein belongs to?
Belongs to the junctophilin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity).
Protein: PDRP1_LISIN
Sequence: MTQPAVYVVSDSTGETAELVTRAALSQFGQTPKFIHRFHHVDSSHMIEEIVDLVAVNNGIIVHTIVLESVREELNKTAQAFGVPIIDLFGPLLNQLEETYKIKPLSEPGRVRSMDEAYFNKVAAIEFAVENDDGRNPRGILQADYVLIGISRTSKTPLSQYLALKGLKIVNIPIVPEAQIPDELFEIDPKKIIGLKISKQKLTKIRQERLISIGLPGAGTYASNQRIDEELAIFNKLASKLNCFVLDVTNKAIEETANEILIHIGEIVDENLEL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 1, PPDK regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: APGM_PYRAB
Sequence: MQRKGILIILDGLGDRPIKELGGLTPLEYANTPNMDKLAKIGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKTYRGRGFFEALGVGLDLDEDDLAFRVNFATLKDGIVVDRRAGRISTEEAHELAKAIQEEVDVGVDFIFKGATGHRAVLVLKGMADGYRVGDNDPHVEGKPPHKFSWEDEESKKVAEILEEFVKKAHEVLERHPINEKRRREGKPVANYLLIRGAGTYPNIPMKFTEQWKVKAAAVIAVALVKGVARAIGFDVYTPEGATGEYNTNEMAKAKKVVELLKDYDFVFLHFKPTDAAGHDNKPKLKAELIERADKMIGYIIDNIDLESTVIAITGDHSTPCEVKNHSGDPVPLLIAGGGVRTDHTERFGEREAMKGGLGRIRGHDIVPIMMDLMNRSEKFGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: APT_COLP3
Sequence: MNKTQQQLLINAIHTIPDYPVEGIMFRDVTSLLEDAEAFKLVMELLENKYKGRGFTKIVGTEARGFLFGAPLALALNIGFIPVRKPGKLPRPTYSQAYQLEYGEDILEIHQDALTPEDNVLIIDDLLATGGTIEATTKLIRRLGAQVQEAGFVISLPDLGGEERLAELNITPYSLIQYQGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_BEUC1
Sequence: MKSAVENLEPTRVKLTVEVAFDELKASLDHAYQHIAQQVNVPGFRKGKVPPRVIDQRVGRAAVVEHAVNDALPDFYRQAVTESELKVLGQPEVEVTGVPDTTSGELTFTAEVDVRPDFTLPALADLELEVDDVAVTDDDVAERLDLLRQRYGTLTGVDRAAETGDYVVIDMTATIDGEEVDTVSGVSYEIGSGNMLDGLDEALVGLAADETATFSAPLAGGDRAGEAADVSVTVTAVKVQELPEADDDFAQLASEFDTLEELQADLRTQISDAKVNNQAVQARDRLLEKLVEATDFPLPQGVIEAEIHRHLESEGRLEDDEHREEVREEATQALRRQLVLDVLADQVSVQVNQNELVEFLLRTAQQYRVDPNEFITNADKTGQIPSFVAELARNKSLAVALRDVRVVDASGNAVDLTSFIGSEETDAEDAAEGVESVEVDLSAAAEDDAEETSDEPAAEDTATEDEAAKA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HBBC_OPHSE
Sequence: VQWSSSERSVISGLWAKVNAAEVGPQALARLLVLYPWTQRYFGKFGDLSSNAALMGNANVAKHGKDLLLADLKAVKNMDNVKALYAKXXXXXXXELNVDPDNFTLLGDCLTIVLAMKFGADFTPVDQAVWQKFVAVVVSGLSKQYF
What is the function of this protein?
Involved in oxygen transport from the gills to various peripheral tissues.
What are the official names of this protein?
Hemoglobin cathodic subunit beta, Hemoglobin cathodic beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SIR5_RAT
Sequence: MRPLPVAPGRLFSQLCCGPKPSASPQSKICLTMARPSSNMADFRKCFANAKHIVIISGAGVSAESGVPTFRGTGGYWRKWQAQHLATPLAFAHNPSQVWEFYHYRREVMRNKEPNPGHLAIAQCEARLRDQGRRVVVITQNIDELHRKAGTKNLLEIHGTLFKTRCTSCGNVAENYKSPICPALLGKGAPEPDTQESRIPVHKLPRCEEAGCGGLLRPHVVWFGENLDPAILKEVDRELARCDLCLVVGTSSVVYPAAMFAPQVASRGVPVAEFNMETTPATNRFRFHFPGPCGVTLPEALAPHETERIS
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting.  Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species.  Activates SHMT2 by mediating its desuccinylation.  Modulates ketogenesis through the desuccinylation and activation of HMGCS2.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.  Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
What are the official names of this protein?
NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Nucleus. Note=Mainly mitochondrial. Also present extramitochondrially, with a fraction present in the cytosol and very small amounts also detected in the nucleus.
Protein: ERGI3_HUMAN
Sequence: MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.  Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin (PubMed:31142615).
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 3, Serologically defined breast cancer antigen NY-BR-84.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: DEOD_ALKMQ
Sequence: MSIHIGAKKGEIAETILLPGDPLRAKFIAENFLENIECYNEVRGMYGFTGSYKGKRISVQGTGMGMPSISIYVNELISDYGVKNLIRVGTCGAMQEEIQLRDVILAMSASTDSNMNKLRFGGMDYAPTASFRLLKKAYDVAQEKGILTRVGNVLTVDTFYNEDVNSWKKWAEFGTLAVEMETAALYTLAAKFGVDALTLLTVSDSLITGGQTTSEERQNTFMGMVKIALELAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ACPS_HALHL
Sequence: MIAGIGTDIVAVVRLERALERHGERFAQRILAPTELLNFREGGATAAFLARRFAAKEAASKALGTGFSDGVTLRDLEVVHDVRGQPSLRFHGAAAERAVALGVSEAALSLSDEREYAVAFVILVTG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y636_BIFLO
Sequence: MNPPIARQLNLDETKLPAEIFERLSRRGATLKDYRRRREEAIENFGKPGRDPAELGSVMTTIAGNGVWAANMKLAQLRNHWDQVVGQAIASHSAVADFTDGVLTIRAESTVWATQLTYLIPQLTDTIRRNLKGLTITEIRVTGPAAGYTRKWARRR
What are the official names of this protein?
UPF0232 protein BL0636.
What is the protein family that this protein belongs to?
Belongs to the UPF0232 family.
Protein: EX7S_XANC5
Sequence: MAKKSLNETSPVARFEQSLEELEQLVQKMEVGDLSLEQSLTAYERGIGLYRDCQQTLEQAELRVRLLTDPARPELAEAFEPPSLDG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_STRPF
Sequence: MKILITGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVFQKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAKAGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFI_GENTR
Sequence: MVSSSVSSVTEVKVESYVFPPSVKPPSSTKSFLLGGAGVRGLEINGNFVKFTAIGVYLEESGVAVLSGKWKGKTAEELSDSVEFFTDIITGPFEKFTQVTLILPVTGQQYSPKVAENCAAQWKAAGIYTDADGIAIEKFLQVFQTESFTPGDSILFTHSPESLTISFGKNGAIPEVSNAVIENKKLSEAVIESIIGEKGVSPAAKKSLATRIAEILNHFDA
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.