PharMolix/UniProtQA huggingface dataset:
Protein: PCKA_METPB
Sequence: MKTIGEFNAAHGPEAIGLTDLTAVHWNLEAPRLYEEALRRGEAQLARGGALVATTGSHTGRSPKDKVVVRDAGTENEIWWDNNGSITREQFATLLEDFRAHARGKELFAQDLYGGADPAHRVRARVYTELAWHSLFIRNLLIRPERGELAAYVPELTIIDLPSFQADPVRHGCRSKTVIAIDFAQKIVLIGGSAYAGEMKKSVFTYLNYVLPGAGVMPMHCSANAALDETGDSALFFGLSGTGKTTLSNDSSRKLIGDDEHGWSRDGIFNFEGGCYAKTIRLSRNAEPEIYATTERFGTVMENVVIDPLTRVPDFDDATLTENTRCAYPLDFIANASATGRAGHPKNIVMLTCDAFGVMPPIARLTGAEAMYHFLSGYTAKVAGTERGLTAPEATFSTCFGAPFMPRHPSVYGNLLRALMAEHGVDCWLVNTGWTGGGVGTGRRMPIRVTRRLLSAALDGSLAQTEFRRDPYFGFSVPVEVAGVETQVLSPVETWTNKAAFAETATRLVTMFRENFKRFESHVDADVRAAEPVAAPIAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP25_PSEMZ
Sequence: DHGESFQMLESGRQMGMNVISAKYNLVTSQTRDSSYK
What are the official names of this protein?
Unknown protein 25.
Protein: ECFA1_LACPL
Sequence: MVSPIIDVKHLDYRYPQQATDQLTLHDISFTVMPGEWVAIVGHNGSGKSTLAKNLNGLLAPAAGTITVDGQVLSEETVWDIRRKIGMVFQNPDNQFVGATVADDVAFSLENQGVPRSEMLTRVQAALEQVNMQDFATREPARLSGGQKQRVALAGMIAARPQILILDEATSMLDPRGRQEVLTTIRDMKANSALTVLSITHDIDEAASANRVLVINDGEVKEEGTPAEIFQHGEALIKMGLDMPYAERLKAALKRQGVQVPAQYLTEKGMADWLWQLRSNK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDXH_XANCP
Sequence: MTDLYAEALATFATLYAEAQNSAEIEASAMTVATANLDGRPSARTVLLKAFDARGFVFYTHLDSAKGRDLQTHPQAALLFLWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASLQSQTLGSREEFEAAIAKVEATFDGRDVPRPDGWGGFRVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CCPR2_USTMA
Sequence: MSKLGDYAAVKKDILAVLKQPEYDDGSAGPVLVRLAWHASGTYCARTDTGGSNGAGMRYEAEGGDPANAGLQHARVFLEPIKEKHSWITYADLWTLAGVVAIEAMGGPSIQWKPGRTDFADDSRLPPRGRLPDGAQGADHLRFIFNRMGFNDQEIVALSGAHNLGRCHSDRSGFEGPWVNSPTRFSNQYYKLLLKLKWQPKKWDGPFQYVAKAPGADDDDEQLMMLPTDYALIQDEKMRPWVEKYAEDRDAFFNDFAKVFAKLIELGVYRDESGIARADKMKQFKGEYKSAPQKSPVPGAPGAGKDGEANPLARQNERAHGQAQHALAKL
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Putative heme-binding peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
Protein: PYRDB_BACC1
Sequence: MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPIIGMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRN1_HUMAN
Sequence: MAAAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISIDQVPRTYAIMISRPAWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERGETAKEALDVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKVTEGVRCICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCGAGKDSLEKQEESITVQTMMNTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRSTMLELEKQGLEAMEEILTSSEPLDPAEVGDLFYDCVDTEIKFFK
What is the function of this protein?
Regulates exocytosis in mast cells.  Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).
What are the official names of this protein?
Secernin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family. Secernin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_STRGC
Sequence: MNTKILETLEFNKIKDLFQGSLQTEQGKLELQVLQPTTKKEAIERAFLEVTDMEQILVEDPHFHLAATKDITAISKRLELDGDLNIEELLVLKKVLRVSHDLVTFYNDLENVRLQELNRIFENLVDFPAIQGSLLAVNDGGFIESFASEELGRIRRKIQENESKVRDLLQEILKNKGDMLADQVVASRNGRNVLPVKNTYRNRIPGVVHDISASGTTIYIEPRAVVNLNEEISNYKADERYELLRILQELSAMIRPHAAEIANNAWIIGHLDLVMAKLAFMRERGAVVPAISDTQAIQLLQVRHPLIQNAVANDLHFGPDLTEIVITGPNTGGKTIMLKTLGLAQIMAQSGLPILADKGSRVGIFSQIFADIGDEQSIEQSLSTFSSHMTNIVSILEQVDSESLVLLDELGAGTDPQEGAALAIAILEDLRLRQIKTMATTHYPELKAYGIETDWVENASMEFDTDSLRPTYRFMQGVPGRSNAFEIARRLGLSEVIVSHAQEQTNTDSDVNQIIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNREKETELNKARLEAQEIVDLALSESESILKNLHAKSSLKPHEIIEAKAQLKKLAPETVDLSKNKVLKQAKKNRAPKVGDDILVTSYGQRGTLVKLLKDGRWEAQVGLIKMTLEEQEFNLLKAEKEQQPKRKQVNVVKRANTAGPRARLDLRGKRYEEAMKELDEFIDQALLNNMAQVDIIHGIGTGVIREGVNKYLRRNKHVKSFGYAPQNAGGSGATIVIFK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: MVP_OLV2I
Sequence: MAGLWRSNSTLDVERGRNRTQTETVQTVPRQAQGILELLSSPAAREALQGSDFARWRGVPVSPAGGYFELAPLRSVNTFARGLRSVFGGSTSRREAYIPQHGFYRLNYVLVAVVPHVEHSDPGEVTVQLVENTNPTRAVDGQELTARLADGSFVFAAAPTYDIVLEQAPILVEGESAGVVQRMFGIRTSVSGSLTTGSVVSVYPIWSAEFPIQGATFNHVAPSIVHIDRFNRSVAFEIDVLRRRFSLMRPLHLARSRESFQVGRMSLDVARPSVVRPPPVDPQAEGGIHVNSPTSEQSQGEDRVPRAGLASGTSVGEGANHEFLSGAVKSTAPVRQT
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: HEMA_I71A3
Sequence: MKTTTILILLTHWVHSQIPINDNNTATLCLGHHAVANGTLVKTLTDDQIEVTNATELVQSTSTGKICNNSYRVLDGKNCTLIDAMLGDPHCDVFQYENWDLFVERSSAFSNCYPYDVPNYALLRSIVASSGTLEFMAEGFTWTGVTQNGGSSSCRRGSADSFFSRLNWLTKSGSSYSTLNVTMPNNDNFDKLYVWGIHHPSTNNEQTKLYVQASGRVTVSTKRSQQTILPNIGLRPWVRGQSGRVSIYWTIVKPGDVLMINSNGNLIAPRGYFKIRAGKSSIMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKITYGKCPKYVKQSTLKLATGMRNIPGKRLRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAGDLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVTLENQHTIDLTDAEMNKLFERTRRQLRENAEDIGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLICVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: ADHS_HALSA
Sequence: MTDAGKTARLNRISTDDRLLTIPMDHGITLGAIDGLVDIEATIREVTANGADAVLTQPGIAPRVHPNKGDAGYIVHLNASTTLGPDQTDKRRTGTVEDAVRAGADAVSFHINVGSDHEPDQITALADVAADADRLGVPVLAMAYARGPGVDEHDAANLGHAVRLAEEVGADVIKTAYSGSTESFQRVVDATAKPVIIAGGDPAGDRETLQGIRDAMDAGAAGVSTGRTVFQHATPGAMTAAISAVVHDDADPEAALARAGLVVDA
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: NUON_CHRSD
Sequence: MTSLLALSPLILVCATAIVVMLTIAWRRHHELTATLTVVGLNLALAAQVVAWWQAPVSVTPLMTVDGLAVFGGVLILIATLACATLGHAYLEGAQGPREEYYLLLLCAAAGGLALVSSRHLAALFFGLELLSMPLYGMLAYTYRERGALEAGIKYMVLSAAASAFLLFGMALLYSRTGHLDFAGLGEALATAGGDGWLMAGMGMMLIGLGFKLSIVPFHLWTPDVYEGSPAPAATFLASASKVAVLLVLLRLLQSSPVQDAWLHSLLAVLAFVTMLVGNLLALTQNDLKRLLGYSSIAHFGYLLVALVVNDGLAAETAALYLVTYVLTTLGAFGVVTLLSSPYSGADASQLHHYRGLFWRRPYLTAVLTVMMLSLAGIPFTAGFIGKFYIVAVGVEASRWWLVGGVVAGSAIGLYYYLRVMVTLFLPEPGMQRRDATTDWAQRAGGVVVLGLAALVVVLGVYPAPMIDWVRFMVAG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAGH_STAAU
Sequence: MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDEARFVIK
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OL486_MOUSE
Sequence: MAFIYNGSQTTVTEFILLGLTDDPVLKVILFCIILCIYLVTVFGNLSTILLIGVSSKLHHPMYFFLSHLASVDMGLSSSVTPNMLVNFLTEKNTISYLGCGIQLSSAAFFGAVEFFLLAAMAYDRLVAICNPLLYSTKMSSQVCIQLVAGSYVGGFLNASFVTHFFFSFLFCGPNRVNHFFCDLSPMMELSCSDVSISEIVISFSAGSFTMTTLFVIVIPYFYIFITILKIRSTEGRQKAFSTCTSHLTAVTLYYGTIIFIYVMPKSTYSRDQNKVVSLFYMLVIPVLNPLIYSLRNNEIKDALKRQFYRKTLL
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 486, Olfactory receptor 204-19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENV_EIAVY
Sequence: MVSIAFYGGIPGGISTPITQQSEKSKCEENTMFQPYCYNNDSKNSMAESKEARDQEMNLKEESKEEKRRNDWWKIGMFLLCLAGTTGGILWWYEGLPQQHYIGLVAIGGRLNGSGQSNAIECWGSFPGCRPFQNYFSYETNRSMHMDNNTATLLEAYHREITFIYKSSCTDSDHCQEYQCKKVNLNSSASSNSVRVEDVTNTAEYWGFKWLECNQTENFKTILVPENEMVNINDTDTWIPKGCNETWARVKRCPIDILYGIHPIRLCVQPPFFLVQEKGIADTSRIGNCGPTIFLGVLEDNKGVVRGDYTACNVRRLNINRKDYTGIYQVPIFYTCTFTNITSCNSKPIISVIMYETNQVQYLLCNNNNSNNYNCVVQSFGVIGQAHLELPRPNKRIRNQSFNQYNCSINNKTELETWKLVKTSGVTPLPISSEANTGLIRHKRDFGISAIVAAIVAATAIAASATMSYVALTEVNKIMEVQNHTFEVENSTLNGMDLIERQIKILYAMILQTHADVQLLKERQQVEETFNLIGCIERTHVFCHTGHPWNMSWGHLNESTQWDDWVSKMEDLNQEILTTLHGARNNLAQSMITFNTPDSIAQFGKDLWSHIGNWIPGLGASIIKYIVMFLLIYLLLTSSPKILRALWKVTSGAGSSGSRYLKKKFHHKHASREDTWDQAQHNIHLAGVTGGSGDKYYKQKYSRNDWNGESEEYNRRPKSWVKSIEAFGESYISEKTKGEISQPGAAINEHKNGSGGNNPHQGSLDLEIRSEGGNIYDCCIKAQEGTLAIPCCGFPLWLFWGLVIIVGRIAGYGLRGLAVIIRICIRGLNLIFEIIRKMLDYIGRALNPGTSHVSMPQYV
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: SYDP_SALTI
Sequence: MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: PA2A1_TRIGA
Sequence: MRTLWIMAVLLVGVEGHLMQFETLIMKVAGRSGVWYYGSYGCFCGAGGQGRPQDASDRCCFVHDCCYGKVNGCDPKKDFYTYSEENGAIVCGGDDPCKKEICECDKDAAICFRDNKDTYDNKYWFFPAKNCQEESEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has high lipolytic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 1, svPLA2, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 isozyme I, PLA2-I.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_LACLA
Sequence: MAVPARHTSSAKKNRRRTHYKLTAPTVTFDETTGDYRHSHRVSLKGYYKGRKVRDTK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RNC_CAEBR
Sequence: MDFTEIHKRSRRKKFQQIHQDRKDEMIQQLGRRFHNQPSTSATYPSAVEDIPLPSEVPNVFGAPPPLTNADFHRNFLVDPDVVVSHSASLIRSNRHIVKAEDAEQYMMVSRERVGTTAERVLEDFNSRVIKPLKAKRRLQIDVPYIDHPLHSMRSKTPERKENEEDSDSEIRSSDSSSDAEYGSDVEEEPDSCRRKKRTHKIQKADSSQTKVEEKERQNTLLRMGIERKRNHPNAIDPHISYNEKGLGNDSPECRCPFPIRNRGLKHGYYAGENQVLKCSKNDRANLHYYTLHVTPAPNESQIQKTQMLINGMEYHFEGFTMVTHAPLPDCMTRRPVFKYSIDYEFQLIEEFMPTECFDPEDCNSIFEYIFHDIFELLDFDLYPKHLPPGTASCPTIHIVPRFVAMENNTTFIWSSKTVLAFFLLHGKNNMFSPEDVEKNCAMSDDAFGRTIAKLKQSIVLNPMKKPSALRADWFSRDLENKEMFLIQNTIRSQNFASPFLPQIAALEKKMSRLKQEKKDSGNKNPHYENLKAELIVLKDKHREARQLKLKLPVKDYIDTGLKPDVVAHVAMAIIASHHIRYNFSLSVFEKVIEYKFNDRRIVELALIHSSFRSYYGTTPDHVKNMISNCGYRKKYGAEERREKKKGIISLFNIMGGETSGGEPILHNERLEYLGDAVVELIASHHLFFILNHHFEGGLATYRTALVQNRNLAKLAMNCRIDEMLQFAHGADLINEAEWKHALANAFEALMAGVFLDSGIAPCDAIFSKAMYGKDPEMKKVWDHLNEHELKIEDPLGDRDLSRITPALTDFHRLEQIIGIEFNNIRLLAKAFTRRNVPFNDLTKGHNQRLEWLGDSVLQLIISDYLYRNFPLHHEGHMSLLRTSLVSNQTQSVVCDDLGFQEFVIKAPHRKNDLKMKDKADLVEAFIGALYVDKGLEYCRSFIRTVFCPRLKHFINSEKWNDAKSHLQQWCLAIRDSRNPNPAMPEYRLLGIQGPTNNRIFRVAVYFRGERLSSAAASNMHTAELKAAENALAALEKASFSRMREKYMSGRQHRLHRIFFS
What is the function of this protein?
Executes the initial step of microRNA (miRNA) processing in the nucleus, that is the cleavage of pri-miRNA to release pre-miRNA.  Involved in pre-rRNA processing.  Cleaves double-strand RNA and does not cleave single-strand RNA.  Involved in fertility.  Required for the function or synthesis of the let-7 miRNA (By similarity).
What are the official names of this protein?
Ribonuclease 3, Protein drosha, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALF1_STAAM
Sequence: MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTADYLADKGVVPFLKVDKGLAEEQNGVQLMKPIDNLDSLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFEVAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTEPNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNDELIASFSRALASDLRADQSKEEFDKALGDAVESIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: MFNG_DANRE
Sequence: MILRRLFHVLPAFAFTLFILVLLDLQLRTRSDQKPQNAHDGHQRTTFISETTAENQHRDGAHEKEKAEGQKWTEVRSTPPLELSDIFIAVKTTGRFHKSRLALLLETWISETKEHTYIFTDSPDADISSEGFNVVVTNCSPEHSHQALSCKMAAEYDYFMASYKKWLCHVDDDNYLNPGALLSLLMAFPADGDIYVGKPSLDRPMRAQELLEGNKTRDVHFWFATGGAGFCLSRNLAERMAPWASGPRFEQTSAVIMLPDDCTVGFIVERRLGISMIHSNMFHSHLENLLLLSPSDIPKQVTLSYGWFESKMNSVELKGVFTKDEDPSRFRTVHCLLYPTTSWCPVALKSALSWNQHVMH
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules.
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: DR7_HHV6U
Sequence: MRHLPFHGMPLRVQMFCAFFIRSETTDKNKATPTITFMVSCCFVWVKRLFYRVGRIHHVQSLTYARPITALDSCLYVCCGYGEKLQPVGFVKSYVTNSQLDTLRVLLVGKDGAVYVHHMRAARLCRLASSTTEFTRRGLQRDAVTYEEDLELPDQRMCGTNARHLFDVIAAAADEHNLLTVGGLCQTHAGVSCNLLETVGDPWTAVPAARMTLTVPQVQYRLWPEARRDLRRHLYAGHPLGPWLVCGVLSRERETQKPSPPIRTTVGNVPTPGPREVEIAWVVLTLAGPLLAFWPDTGKICRLANSFSTLWKMGPRAMRGHWTYSAPGRHLPGDAWPLCEHVRPQWKASEEESVPGLDATEVK
What is the function of this protein?
Involved in transactivation (Probable).  Displays transforming activity.
What are the official names of this protein?
Uncharacterized protein DR7.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: DBP4_ASPCL
Sequence: MAPTTGPRNTKNAKPAVQRSKTLKRKRGQEELSSLIQRVEGLDLKESFESFSDLPLSEPTLSGLTSSHFKTLTDIQSRAISHALKGRDVLGAAKTGSGKTLAFLVPVLENLYRRQWAEHDGLGALILSPTRELAIQIFEVLRKIGRYHTFSAGLVIGGKSLREEQERLGRMNILVCTPGRMLQHLDQTALFDTYNLQMLVLDEADRILDLGFQQTVDAIVGHLPKERQTLLFSATQTKKVSDLARLSLRDPEYVAVHETASTATPAKLQQHYVIAPLPQKLDILWSFIRSNLKSKTMVFFSSGKQVRFVYESFRHMQPGIPLMHLHGRQKQGGRLDIMTNFSQAKHCVLFSTDVAARGLDFPAVDWVIQMDCPEDADTYIHRVGRTARYGRDGRAVLFLDPSEEEGMLKRLEQKKVPIEKINIKANKQQSIKDQLQNMCFKDPELKYIGQKAFISYVKSVYIQKDKEIFKLKELKLDEFASSLGLPGAPRIKFIKGDDTKQRKNAPRAAAHLSSDDEAGSDAEEGEPKTKKKEEPQVRTKYDRMFERRNQDVLAEHYSKLINDDGTMVAPPNAGAGADADEDDDFLSVKRRFDVGDETLGMSSDDSDEEDDDDDETSPKKETKVVHIDGKEALVIDSKRREKLLKSKKKLLKFKGKGTKLVYDDEGNAHEVYELEDEDQFKARGDAKEQKAKFLEEEAERTRLADLEDKEIAKQKRREKKEKRKARERELLAEAEDEEETVVQLPPYEGDHDMDGGFSASEEEEEAARPSKKPKVKFAEPDESDKGSEPWYKKSKRTDDKGGSQAPQIQTLEDLESLASGLLG
What is the function of this protein?
ATP-dependent RNA helicase required for ribosome biogenesis.  Involved in the release of U14 snoRNA in pre-ribosomal complexes.  Required for pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: THPR_PYRFU
Sequence: MRAFIAIDVSESVRDALVRAQDYIGSKEAKIKFVERENFHITLKFLGEITEEQAEEIKKILEKIAKKYKKHEVNVRGIGVFPNPNYVRVIWAGVENDEIIKKIAKEIDDELAKLGFKKEGNFVAHITLGRVKFVKDKLGLAMKLKELANEDFGSFIVEAIELKKSTLTPKGPIYETLARFELSE
What is the function of this protein?
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.  In vitro, ligates 5' and 3' half-tRNA molecules with 2',3'-cyclic phosphate and 5'-hydroxyl termini, respectively, to the product containing the 2'-5' phosphodiester linkage.  Ligase activity requires GTP, but GTP hydrolysis is not required for the reaction, which is reversible.  Ligase activity is weak compared to the phosphodiesterase activity.
What are the official names of this protein?
RNA 2',3'-cyclic phosphodiesterase, RNA 2',3'-CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. ThpR family.