PharMolix/UniProtQA huggingface dataset:
Protein: YCX2_SCHPO
Sequence: MGFKLNPFSKKPKDEEPLPLEQYEASEQKILGLVTKKEAKLLAIAGTGFLLDSYDLFIINLVSPILAYLYWGGLTGHQDYPSGIRGVVNAATNIGNIMGQLLFGFLGDFFGRKFVYGKEMMVVIIATILIICLPDRIPTPTAKMMWLFAFRVMLGIGIGGDYPMSASITSEQSLINRRGALLAWIFSNQGWGTLAGCVATLIILACFEKPLNDRGEYTKLNGVWRIQFGIALFPAVIVLIPRLRMQESEQFKNSKNMKSPGEGDLDSASQIELHDFKKKESLTAEFTTSSPSTASLSDKKNPGSVHIRPNNEVAPSSAPSRAPSTTSVESNTEGKESDIQTGSSFVSYFKEWRHAKLLIGSALSWFLLDIAFYGINLNQSVILQEMGFNKGVNEYHILQKNAIGNLIIAVAGYIPGYWVSVVLIEVMGRKWIQIQGFLICCLLFGVLAGTWETISTGGRFACVALAQFFFNFGPNTTCFVIPAEVFPSRVRAFSHGICAACGKAGAILSALLFNKLTEVIGFGNVLWIFFGCMVAGAVVTLILPETANRDADLIDRLEIAAMQQGRTSIIDRSEKWAWWKHGI
What are the official names of this protein?
Probable metabolite transporter C2H8.02.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Membrane; Multi-pass membrane protein.
Protein: CAPP_TOLAT
Sequence: MNDMYAALRGNVGMLGHLLGKTIKEHLGDEFLDKIENIRQLAKSSRQGNEEDRQKLITTLKNLSDDELLPVARAFSQFLNLANVAEQFHSMSRQGELHTTLDPLDSLFDKLKNANLSEQEIIDTVCELDIELVLTAHPTEVTRRTLIHKHVQLNECLEELELQDLTPRECKFIQHRIEQLVNQSWHTNEIREQRPTPVDEAKWGFAVIENNLWPAIPLFLRQLDDRLQENFGIRLPLRAHPVRIASWMGGDRDGNPFVTAKVTQEVLLLSRWVAINLFLTDIQELVSELSMTDCNEELRQRVGECSEPYRAILRVVRDSLRETQQAVTAKLQGQYTENRDLITRTEQLREPLELCYRSLQSCGMSIIADGMLLDVLRKLACFGVNLLKLDIRQDGERHGQVLSELTQYLELGDYAEWRETEKQEFLLKELASRRPLLPANWQPSAESQEVVDTCRVIAQTDPDAFGIYIISMARQPSDVLAVQLLLKEVGCKFHMPIAPLFETQNDLQNAAAVLNRLLSVEWYRNYIRGQQYVMIGYSDSAKDAGMMSAGWAQYRAMEDLVAIAEREDLKLTLFHGRGGTIGRGGGPAHQAILSQPPGSLKGGFRVTEQGEMIRFKFGLPEVAIHNFKLYTSAVLEANLLPPPKPEAAWYDVMDKLSEISCQHYRSIVRDEPDFVPYFRAATPEMELGKLPLGSRPSKRKPNGGVESLRAIPWIFAWTQNRLMLPSWLGAHVALQAVMDEGKEDLLKEMDQQWPFFHTRLEMLEMVFLKADLWLAEYYDLRLAPENLWPLGKRLRQELQDSINVVLQLLPKRGELLDDQPWIKESIKLRNPYTDPLNVLQVELLHRSRATPDEVNPQVDQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: MURA_SINFN
Sequence: MDRIRIVGGNQLHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGADISVNGRRERQGESYARTIHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGKARVSLPGGCAIGTRPVDLFIEGLTALGANIEIDGGYVNATAPEGGLTGGRYVFPKVSVGATHVLMMAATLANGTTVIGNAAREPEVADLAKCLNAMGAKITGAGTGTITIEGVRSLSGARHRVLPDRIETGTYAMAVAMTGGDVILEDTEASLLDTALEAIRRAGAEISETNSGIRVVRNGAGIRPVDIVTDPFPGFPTDLQAQFMGLMTKSSGVSHITETIFENRFMHVQELARLGAKISLSGQTAKIEGVGRLKGAPVMATDLRASVSLVIAGLAAEGETMVSRVYHLDRGFERLEEKLTRCGAHVERVSD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BARBK
Sequence: MQSYDVIIVGGGHAGCEAASASARTGARTALVTYRLSDMGTMSCNPAIGGLGKGHLVREIDALDGLMGRAADFAGIQFRLLNRRKGPAVRGPRTQADRQLYKKAIQKLLREQDNLFIIEDEVVDIIVKNNRVSGVFLKNQGNIFSGAVVLTTGTFLNGLIHIGDKTWPAGRMGEQASVQLAERLKNYGISFGRLKTGTPARLSKKTIRWDVLPKQQADEDPVPFSFLTEKIKQPQIECAITRTNAQTHHIISENIHRSALYSGAIEGVGPRYCPSIEDKIIKFGERDGHQIFLEPEGLEDDVIYPNGISTSLPEDVQISLLKTIEGLENVNVLQPGYAIEYDFINPQYLSKTLELRSLPGLFLAGQINGTTGYEEAAAQGLLAGLNAARQVGGLDEIILSRSTAYIGVMIDDLISRGVCEPYRMFTSRAEFRLSLRADNADARLTPLAQEWGIVSHKRWTCYQNKQQRLDHARSICQKLFLTPNEASAHGLQINNDGVRRSAYSLLSYPNMNVARLTDFWPQLHSIDAKTVESLEIEAQYAVYLERQKQDIAALQRDESLEIPSSLNIQAIYGLSNELKTKIQKISPRSIADAQKIDGMTPAALSLIITYIQRQRREKGKLA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REPE1_ECOLI
Sequence: MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEEDAGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG
What is the function of this protein?
Replication initiator in the monomeric form, and autogenous repressor in the dimeric form.
What are the official names of this protein?
Replication initiation protein, Protein E, Protein rep, Protein F4.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: DER_LACP3
Sequence: MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGGIDLGDEPFLAQIKDQAEIAIDEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNKVDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVLAAFPSEDKSVEDDSIKFSLIGRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYENTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEKDNHTMKDFENLIRQEFQYLDYAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLNDVLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVNDPDLLHFSYERFLINQLRQAFDFSGTPIHIIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SIX3_CHICK
Sequence: MVFRSPLELYPTHFFLPNFAADPHHRSLLLASGGSGSGSGCSPGAGGGGGSSRAPHEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGQSGMRSLAEPGCPTHSSAESPSTAASPTTSVSSLTERAETGTSILSVTSSDSECDV
What is the function of this protein?
Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes.  During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon (PubMed:12569128).  Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression.  In addition, Six3 activity is required for the formation of the telencephalon.  During postnatal stages of brain development is necessary for ependymal cell maturation by promoting the maturation of radial glia into ependymal cells through regulation of neuroblast proliferation and migration.  Acts on the proliferation and differentiation of neural progenitor cells through activating transcription of CCND1 and CCND2.  During early lens formation plays a role in lens induction and specification by activating directly PAX6 in the presumptive lens ectoderm.  In turn PAX6 activates SIX3 resulting in activation of PDGFRA and CCND1 promoting cell proliferation.  Also is required for the neuroretina development by directly suppressing WNT8B expression in the anterior neural plate territory.  Its action during retina development and lens morphogenesis is AES and TLE4-dependent manner (PubMed:12050133).  Furthermore, during eye development regulates several genes expression.  Before and during early lens development represses the CRYGF promoter by binding a SIX repressor element.  Directly activates RHO transcription, or cooperates with CRX or NRL.  Six3 functions also in the formation of the proximodistal axis of the optic cup, and promotes the formation of optic vesicles-like structures.  During pituitary development, acts in parallel or alternatively with HESX1 to control cell proliferation through Wnt/beta-catenin pathway.  Plays a role in eye development by suppressing WNT1 expression and in dorsal-ventral patterning by repressing BMP signaling pathway (By similarity).
What are the official names of this protein?
Homeobox protein SIX3, CSIX3, Sine oculis homeobox homolog 3.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_KLEP7
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYEALEVQNGNEVLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGQPVDMKGDIGEEERWAIHRAAPSYEELSSSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVALKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MALF_ECO57
Sequence: MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGREQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltose/maltodextrin transport system permease protein MalF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VDAC3_ARATH
Sequence: MVKGPGLYTEIGKKARDLLYRDYQGDQKFSVTTYSSTGVAITTTGTNKGSLFLGDVATQVKNNNFTADVKVSTDSSLLTTLTFDEPAPGLKVIVQAKLPDHKSGKAEVQYFHDYAGISTSVGFTATPIVNFSGVVGTNGLSLGTDVAYNTESGNFKHFNAGFNFTKDDLTASLILNDKGEKLNASYYQIVSPSTVVGAEISHNFTTKENAITVGTQHALDPLTTVKARVNNAGVANALIQHEWRPKSFFTVSGEVDSKAIDKSAKVGIALALKP
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
What are the official names of this protein?
Mitochondrial outer membrane protein porin 3, Protein HYPERSENSITIVE RESPONSE 2, Athsr2, Voltage-dependent anion-selective channel protein 3, AtVDAC3, VDAC-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
Protein: THIE_XANC8
Sequence: MPTLQNARGVYLITPDTRDTAQLLACTLPLLPHITWLQYRNKQADAALRLAQATALRAACTAHGVPLIINDDAALAQQVGADGVHLGEDDGEVAAARALLGASAIIGVSCYDEIERARAAAAAGANYVAFGAFFPTATKVTTRRATPALLHEAAALGLPRVAIGGITPSQVPELVTAGADLIAVVSGVYAAADPVAAVQAYRAGFTQ
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TEX29_HUMAN
Sequence: MEYVLEVKNSPRHLLKQFTVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELASSSSKLGLKPASPGPPSAGPSMKSDEDKDDVTGTITEAEETED
What are the official names of this protein?
Testis-expressed protein 29.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COPZ_STAA9
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_LEGPL
Sequence: MSLLKEFKEFAMRGNVMDLAVAVVMGVAFNKIVTALVDGIIMPCVGLLLGGVNIAGLSFTVGDAQIKWGNFLQNVIDFIIVAFAIFILIKLINLLQRKKANEPEPVTPEVQLLTEIRDLLARNSSKI
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SNF5_XENTR
Sequence: MIMALSKTFGQKPVKFQLEEDGEYYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKYHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENAAQSEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFAEILCDDLDLNPLAFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
What is the function of this protein?
Involved in chromatin-remodeling.  Core component of the BAF (SWI/SNF) complex.  This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation.  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YEPC_SCHPO
Sequence: MRIIALPLPNQRVFLHCYPSEYLAKKVTIHDKIINRIYKYWDSWSASKSYTKQKVVSLGNRILHATPYEENFLRAIAPVKKLNDTELHQTLYIEHPPNLESSTILAELNRSKQLQKTHTNYLIGNIIGLPLTIPFILIPLIPNIPGFYLCYRAYCNFRAIQGSIQLARVMSIENIQMQESEKLEKALKLFTNGDATPLNALIGHPDFVDRYKRAVAQEQRKSKIIK
What are the official names of this protein?
Uncharacterized protein C23H3.12c.
What is the protein family that this protein belongs to?
To yeast YDL183c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PDXT_SULIM
Sequence: MKIGIIAYQGSFEEHYLQLKRAFDKLSINGEITPVKIPKDLKDIDGVIIPGGESTTIGLVAKRLGILDELKEKITSGLPVMGTCAGAIMLAKEVSDAKVGKTSQPLIGAMNISIIRNYYGRQRESFEAIIDLSKIGKGKANVVFIRAPAITKLWGKAQSLAELNGVTVLAEENNILATTFHPELSDTTSIHEYFLHLVKG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: BUR1_YARLI
Sequence: MHGQPHQHLHTSPTAPFNMTIPYQPSTYYGCSNVTESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHENVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLGNQSVQLSPAHIKCYMLQLLEGIGYLHAKKFLHRDIKAANILVNDQGILKLADFGLARGYDGPAPNSQTAGVNTENLTAMVVTRWYRPPELILGDRKYTTAIDMWGIGCVFGEFFTRKPIFPGASDVDQGSKIFQAVGVPTEDTMPGWSVLPGAQNSNIWGTDATNKLDKLFGRLSKDGLDFLKGLLLLDPTKRLTAIGGKNHAYFKTEPLPCQPHELPKWQSSHELDNHKRREQEKNESKVQPPPREKQPPVREPRDRDRSRDSRPPRERDSRDRRPPRGRYDSFERPERRPEGPRDGPRDRDRDEYPRELPPRDLPPRDLPPRDRDYPPRERDWDRRPPPRDRDYPPRERDYPPRDSRDRDYHPRDRDYPPRDSRDYPRDSRDSRDSRPISPSRERFHKRPQFDMYSDTDYDRERDEDDRRRRPLPRDSSRDMTRDVYVPSRGREPRELPKGPPPAPGDKVEDKGESHNKDDKPCDTENPRDSDKSRDLGPPPGPPLPADGPPPPPSSNPPRPSETYGGSRPPWRRDSRDRRESRDRDGRDRDGRDRRLSSSRYARDEFDEYGRKRPRIER
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation.  Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase BUR1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYDND_SYNPW
Sequence: MRSNGCGDLRKEHIDNSVQLCGWVDRRRDHGGVIFIDLRDRTGTVQITVDPDLGAEAFAVAEHLRSETVLQISGKVRARPAESLNEKLATGAVEVLASGITVLNSVKGNLPFPVSVHDEENTREELRLRHRYLDLRRKRMNDNLRLRAQTIQAARRFLEDEGFIEVETPVLTRSTPEGARDYVLPSRVCGGEWFALPQSPQLFKQLLMVGGIERYYQVARCFRDEDLRADRQPEFTQLDIEMSFMDQEEILQLNESLICSIWKAVKGIDLPRPFPRMTWHDAMERYGTDRPDTRYGMELTNVSDIVKDMGFKVFSGAVKNGGAVKCIAVPGGNEALSNVRIKPGGDVFSEAQKAGAGGLAFIRVRDGGEIDTIGAIKDNLSDEQKQELLSRTGAEPGTLLLFGAGDTATVNKALDRVRQYLAKELGMVKADRDNDQWNFLWVVDFPMFEFNSDENRYEALHHPFCAPNAEDLGSDASQWADTLPGARAQAYDLVLNGLELGGGSLRIHDSALQRQVLQTVGLPLEEAQEQFGFLMDALDVGAPPHGGLAFGVDRMVMLLAGEESIRDTIAFPKTQQARCLMTNAPGGVADKQLEELHVASTWVDPTEEDSN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSE3_YEAST
Sequence: MSSIDNDSDVDLTEDLAVAKIVKENPVARKMVRYILSRGESQNSIITRNKLQSVIHEAAREENIAKPSFSKMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLEEKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI
What is the function of this protein?
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage.  Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
What are the official names of this protein?
Non-structural maintenance of chromosome element 3, Non-SMC element 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ORN_BUCBP
Sequence: MNTDIKNLIWIDLEMTGLNPNIHKIIEIATLITDKNLKILSYGPVIAIYQNNHQLSFMDPWNNKMHTKNGLITRIKNSLYTEHLAEIKTITFLKKWVPKNTSPMCGNSISTDRQFLFKYMPTLEKYFHYRQIDVSTIKELALRWKPKIYNKLKKKTLIKH
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRNF_AERHY
Sequence: MSRPSRVLGLPLLSLGLTLLVSTPLQAQEAQTFRAVKQDLVKLYQSHPSTFYCGCNIKFSGKKMAPDWESCGYLPRKQANRAARIEWEHVVPAWEFGHQLQCWQEGGRKNCGKSAEFNKMEGDMHNLFPAIGEVNGDRANYRFSDWNGKPNQYGKCQMLVDFKEQRVQPPKGPVRGQIARAYLYMGEQYGLRLAAQQRKLFEAWDRQYPADRWECERNRRIGKLQGNTNPFIEKQCQ
What is the function of this protein?
Endonuclease which is capable of degrading plasmid DNA.
What are the official names of this protein?
Periplasmic deoxyribonuclease, DNase.
What is the protein family that this protein belongs to?
Belongs to the EndA/NucM nuclease family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PHYB_ORYSI
Sequence: MASGSRATPTRSPSSARPAAPRHQHHHSQSSGGSTSRAGGGGGGGGGGGGGAAAAESVSKAVAQYTLDARLHAVFEQSGASGRSFDYTQSLRASPTPSSEQQIAAYLSRIQRGGHIQPFGCTLAVADDSSFRLLAYSENTADLLDLSPHHSVPSLDSSAVPPPVSLGADARLLFAPSSAVLLERAFAAREISLLNPLWIHSRVSSKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVRAISRLQALPGGDVKLLCDTVVEHVRELTGYDRVMVYRFHEDEHGEVVAESRRNNLEPYIGLHYPATDIPQASRFLFRQNRVRMIADCHAAPVRVIQDPALTQPLCLVGSTLRSPHGCHAQYMANMGSIASLVMAVIISSGGDDDHNISRGSIPSAMKLWGLVVCHHTSPRCIPFPLRYACEFLMQAFGLQLNMELQLAHQLSEKHILRTQTLLCDMLLRDSPTGIVTQSPSIMDLVKCDGAALYYHGKYYPLGVTPTEVQIKDIIEWLTMCHGDSTGLSTDSLADAGYPGAAALGDAVSGMAVAYITPSDYLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFKAFLEVVKSRSLPWENAEMDAIHSLQLILRDSFRDSAEGTSNSKAIVNGQVQLGELELRGIDELSSVAREMVRLIETATVPIFAVDTDGCINGWNAKVAELTGLSVEEAMGKSLVNDLIFKESEETVNKLLSRALRGDEDKNVEIKLKTFGPEQSKGPIFVIVNACSSRDYTKNIVGVCFVGQDVTGQKVVMDKFINIQGDYKAIVHNPNPLIPPIFASDENTCCSEWNTAMEKLTGWSRGEVVGKLLVGEVFGNCCRLKGPDALTKFMIVLHNAIGGQDCEKFPFSFFDKNGKYVQALLTANTRSRMDGEAIGAFCFLQIASPELQQAFEIQRHHEKKCYARMKELAYIYQEIKNPLNGIRFTNSLLEMTDLKDDQRQFLETSTACEKQMSKIVKDASLQSIEDGSLVLEKGEFSLGSVMNAVVSQVMIQLRERDLQLIRDIPDEIKEASAYGDQYRIQQVLCDFLLSMVRFAPAENGWVEIQVRPNIKQNSDGTDTMLFPFRFACPGEGLPPEIVQDMFSNSRWTTQEGIGLSICRKILKLMGGEVQYIRESERSFFHIVLELPQPQQAASRGTS
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome B.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: ADHL_GADMO
Sequence: ATVGKTIRCRAAVAWEAGKPLSMEEVEVAPPQAGEVRIKIVATGICHTDAYTLSGSDPEGVFPSVLGHEGAGIVESVGEGVTKFKSGDAVIPLYVPQCGECKFCKNPKTNLCQKIRLTQGKGLMPNGTSRFSCNGQVLFHFMGSSTFSEYTVVAEISLAKVHEKAPLDKVCLLGCAISTGYGAALNTAKVEAGSTCAVFGLGALGLAVIMGCQAAGASRIIAIDVNPDKFRIAKEFGATDLVNPKDHSKPVEQVLVEMTDGGVDYSFECVGNIAVMRAALEACHKGWGTSVIIGVAAAGQEISTRPFQLVTGRTWKGTAFGGYKSVESVPKLVEEYMNKKVKVDEFVTHTLPFEKIHEGFDLMGAGKSIRTVLNY
What is the function of this protein?
Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
What are the official names of this protein?
Alcohol dehydrogenase class-3 chain L, Alcohol dehydrogenase class-III chain L, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.