PharMolix/UniProtQA huggingface dataset:
Protein: CDKL3_MACFA
Sequence: MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRVIKVKGGRGDISEPKKKEYEGGLCQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKENPHCGGSMTMPPINLTNSNLMAANLNSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQEDPGPIQSQMGKGIFNERTGHSDQMSNENKRKLNFSRSDRKEFHFPELPVTIQPKDTKGMEVKQIKMLKRESKKTDSSKIPTLLNVDQNQEKQENTGNAQTERKKNLPDVE
What are the official names of this protein?
Cyclin-dependent kinase-like 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR1_MOUSE
Sequence: MAASAVCRAACSGTQVLLRTRRSPALLRLPALRGTATFAQALQSVPETQVSILDNGLRVASEQSSHATCTVGVWIDAGSRYETEKNNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLADIVQNSSLEDSQIEKERDVILREMQENDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLNRHYKAPRMVLAAAGGVEHQQLLDLAQKHLSSVSRVYEEDAVPGLTPCRFTGSEIRHRDDALPLAHVAIAVEGPGWANPDNVTLQVANAIIGHYDCTYGGGVHLSSPLASVAVANKLCQSFQTFNISYSDTGLLGAHFVCDAMSIDDMVFFLQGQWMRLCTSATESEVTRGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIQEVDAQMLRDICSKYFYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity).  The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties.  May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (By similarity).  Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RR12_DRIGR
Sequence: MPTIKQLIRNTRQPIKNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL34_MESH2
Sequence: MKRTYQPNKRKHLKTHGFRARMSTADGRKILAARRAKGRKRLTVSDK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: COBD_THEAC
Sequence: MIIILIGAIAIDIIFGEPKEYIHPVVFSGKVSKRIETYFRHHDNRIVYGSIFAVAVIVITAIPYFLAIYVSSFVLVIYVIVSMVILKTTFSISAMGDHIRLVVESLKNGNISDARVYLSRVVRRDTSNLNENEISSAAIETIAEGLVDGYMTPLFFFIFLGIPGAFVARIINTLDSMCGYKDRENFEFGRFSAFMDTVINYIPARLSWFFIGFSADVLNYRHKVISPRKYVSRFDSVNAGWPISTMACALNLRLEKRGSYIVNDEGYQPSVRDIERSMHVFYVAVYSYTIIFVLPLLVAMAFLL
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Probable cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CASP_ARATH
Sequence: MEVSQDGSERDKTPPPSSSSSSSSPIPVVTNFWKEFDLEKEKSLLDEQGLRIAENQENSQKNRRKLAESTRDFKKASPENKLSMFNSLLKGYQEEVDNITKRAKFGENAFLNIYQKLYEAPDPFPALASIAEQDRKLSEVESENRKMKVELEEFRTEATHLKNQQATIRRLEERNRQLEQQMEEKIKEVVEIKQRNLAEENQKTMELLKDREQALQDQLRQAKDSVSTMQKLHELAQNQLFELRAQSDEETAGKQSEVSLLMDEVERAQTRLLTLEREKGHLRSQLQTANEDTDNKKSDNIDSNSMLENSLTAKEKIISELNMEIHNVETALANERESHVAEIKKLNSLLNKKDTIIEEMKKELQERPSAKLVDDLRKKVKILQAVGYNSIEAEDWDAATTGEEMSKMESLLLDKNRKMEHEVTQLKVQLSEKASLLEKAEAKGEELTAKVNEQQRLIQKLEDDILKGYGSKERKGALFDEWEFSEAGVAEQSEPMDQKHVPSEQDQSSMLKVICSQRDRFRARLRETEEEIRRLKEKIGFLTDELEKTKADNVKLYGKIRYVQDYNHDKVVSRGSKKYVEDLESGFSSDVESKYKKIYEDDINPFAAFSKKEREQRIKDLGIRDRITLSSGRFLLGNKYARTFAFFYTIGLHVLVFTCLYRMSAYSYLSHGAEETLMTEATTNLPHGL
What is the function of this protein?
May be involved in intra-Golgi transport.
What are the official names of this protein?
Protein CASP.
What is the protein family that this protein belongs to?
Belongs to the CASP family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: AROC_PYRAE
Sequence: MNTFGREFRITTFGESHGKAVGVVIDGVPAGLPLSEEDIKRELERRMFCHIHWLNPRCEPEEFEILSGVKNGHTQGTPIAIVIWNKRAISSYYDELWMKPRPGHADLAYYLKYGKFYDHRGGGRASGRTTAAIVAAGAVAKKLLSQLGVDVCGHIIELGGIEVRRSYTFEEVKSSWAKPLPVVDDEALAAMLETLRKNAAEGDSVGGGVEIWAVGVPPGLGEPHFGKIKAELAMAAFSIPAVVALDWGAGRALAKMRGSEANDPIIIKSGRPALESNKIGGVLGGITVGEPIYFRVWFKPTPSVRKPQRTVDLAKMEPAVLEFKGRYDVSVVPKALVALEAMTAITLADHALRAGLVRRDRPLRDPVV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SYSC_MACFA
Sequence: MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVEDDESVPENVLNFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKAAARDVALESRLQNMEVTDA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser).  Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).  In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC.  Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16).  Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA.
What are the official names of this protein?
Serine--tRNA ligase, cytoplasmic, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, but a minor proportion is also found in the nucleus.
Protein: FKBPL_HUMAN
Sequence: METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG
What is the function of this protein?
May be involved in response to X-ray.  Regulates p21 protein stability by binding to Hsp90 and p21.
What are the official names of this protein?
FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39.
Protein: ISPF_SHEHH
Sequence: MKIRIGHGFDVHKFGGEPPLILGGVDVPYEVGLIAHSDGDVALHAISDAILGAMALGDIGKHFPDTDPEFKGADSRVLLRHCYQLATDMGFSLSNLDVTIIAQAPKMAPHIEAIRKVLAADLVADINDINVKATTTEKLGFTGRKEGIAVEAVVLMIKA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PTXC_ECOLI
Sequence: MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTDPNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFINAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDKKLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWVYTFLERILIPTGLHHFIYGQFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGGFALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLID
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  This operon may be cryptic in wild-type K12 strains (Probable).
What are the official names of this protein?
Phosphotransferase IIC component GlvC, PTS system EIIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=When overexpressed using vectors that provide a promoter and ribosome binding site (PubMed:15919996).
Protein: NMT4_PAPSO
Sequence: MDSKDQHGTKILERLVKGEIGDEELKELIRIRFEKRLQCGYKPTPQDQLASEMAFIKSLKDMKMSGELEAVNTELYELPTAAVAATLGSTLKQSACYFKEESMSIDEAEIAAYELDCERAQIKDGQTILDIGCGFGGLVLHIAQKYKNSHVTGLTNSAEQRNYIMLQVEKLSLSNVDVILADVTKHEFENEKKFDRILVVEAIEHMKNIQLFLKKISNWMKDEDSFLFVVHLCHKAFSQHFEALDEDDWYTSYVLPEGSVTYLSASALLYFQDDVSVVDQWLLSGTHMARSQEEWFKRFKINLEAASKALTVGLGSEEAANQVNIQYKTFFMGYVVQFSFNNGEEWMISHYLFKKK
What is the function of this protein?
Probable N-methyltransferase not involved in benzylisoquinoline metabolism.  Shows no detectable activity with (s)-coclaurine, (R)- or (S)-reticuline, papaverine or (R,S)-tetrahydropapaverine.
What are the official names of this protein?
N-methyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
Protein: SURE_CUPNH
Sequence: MHILLANDDGYLAPGLAVLHAALAPLGRITVIAPEQNHSGASNSLTLQRPLSIYEAREGVQKGFRFVNGTPTDCVHIALTGLLEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLLGIPSVAFSQVDKGWEHLDAAARVARTVVERIIGTPPAEPFLLNVNIPNLPFEHIKGYRATRLGKRHPSQPVITQVNPRGDTNYWIGPAGDARDASEGTDFHAAAAGYVSLTPLQLDLTHRGQLDALDQWLK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_SHEB5
Sequence: MKERKFFGTDGIRGKVGSGQMTPELALKLGWAAGRVLSRSGTKKVIIGKDTRISGYMFESALEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSTDGSKLDDNLELEIEAELEKPLVCVESHLLGKVSRIEDARGRYIEYCKGNFPAEHTLTGLKIVVDCAHGATYHIAPAVFRELGAEVIAIGDKPNGMNINDKVGATSMGKICETVIAESADLGIALDGDGDRIMMVNSKGEVIDGDQILYILACDAKSRGVLRGGVVGTLMSNLGLDLALQALDIPFARSKVGDRYVMELLKELDWRIGGENSGHILNLDHGTTGDGIVAGILVLAAMRRQNATLEELTSAMEMLPQVLVNVRFEGEHDPLKSDKVKAAQAQVESELGVRGRVLLRKSGTEPLIRVMVEGDDHSAVLAHANLIADAVKSAS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ENO_RHOOB
Sequence: MSIIEQVGAREILDSRGNPTVEVEVLLDDGSFARAAVPSGASTGEHEAVELRDGGDRYNGKGVEKAVEAVLSEIAPAIIGIDATEQRTVDQALLDADGTPDKSRLGANALLGASLAVARAAAESSGLDLFRYVGGPNAHVLPVPMMNILNGGAHADTGVDVQEFMVAPIGAATFKESLRWGAEVYHALKSVLKEKGLATGLGDEGGFAPDVAGTKEALDLISLAVGKTGLVLGTDVALALDVAATEFYTDGTGYKFEGSNRTADEMAAFYAELVDAYPIVSIEDPLDEDDWDGWVALTDQIGNKVQLVGDDLFVTNPERLEEGIVKGAANALLVKVNQIGTLTETLDAVDLAHRNGYKTMMSHRSGETEDTTIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEENLGDAARYAGEVAFPRFAFEG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPE_HELPJ
Sequence: MALLKISVVVPEGEVYTGEVKSVVLPGVEGEFGVLYGHSNMITLLQAGVVEIETENQKEHIAINWGYAEVTNERVDILADGAVFIKKGSDDRDDAISRAKKLLEDASSDRLAVSSVLAKIESL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COR1C_DANRE
Sequence: MFKRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTGRIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMSEPVVVLEGHSKRVGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSICWNRNGSLICTACKDKKIRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDGKVFTTGFSRMSERQLALWDPENIDEPVAVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDVNKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGDPVLISLKHGYIPGKNRDLKVVKKNILDNKMSKNTENTTPAHKTATSTPSIKSEAKLEEVLKEIKSLRELVSSQEKRIGKLEEQLSKMDI
What is the function of this protein?
Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (Probable).  Increases the presence of activated RAC1 at the leading edge of migrating cells.  Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments.  Plays a role in endoplasmic reticulum-associated endosome fission: endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.  Required for normal cell proliferation, cell migration, and normal formation of lamellipodia.  Required for normal distribution of mitochondria within cells (By similarity).
What are the official names of this protein?
Coronin-1C-A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Endosome membrane. Note=Colocalizes with the actin cytoskeleton in the cytosol, and especially in the cell cortex (By similarity). Colocalizes with F-actin at the leading edge of lamellipodia (By similarity). Partially colocalizes with microtubules and vimentin intermediate filaments (By similarity). Localizes to endosome membrane tubules/buds (By similarity).
Protein: 2A5B_RAT
Sequence: METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYELEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWRGLEELRLRRLQGTQGAKEAPVPRPTPQVAASGGQS
What is the function of this protein?
As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation.  The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_POLNA
Sequence: MQVELLNDQGLSSSKVDVSDTVFGREYNESLIHQVIVAFQANARQGTRAQKDREQVRHSTKKPFKQKGTGRARAGMTSSPLWRGGGRIFPNMPDENFTHKINKKMYRAGMASIFSQLAREGRLAVVDSLTVDSPKTKVLADKFKAMNLNSVLVIADQVDENLYLASRNLVNILVVEPRYADPLSLVHYKKVLVTKAAMDQLKEMFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ARLY_YERPA
Sequence: MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_ACIC1
Sequence: MTLAAQPHVLAVEVDIGTHETAKFLGLTWHWDTILTSVIAGVIVVGLGLYMRWTARSGVPSKMQLLFEMLVSWVNRQVEESMGLRVAPFVAPMAVTLFVYILLCNWIGVLPSGHPEHLPAPTADINLTLTLALVVIVPMHIVSLKRRGLGRYIRHYFEPYKIFFPINVVEELAKPITLALRLFGNIFSGAIMVSLLALMPPYVLWLPQWLWKLIDLGVGVIQAFIFALLTILYYAFATATGGHGASDEHADGGDSSSRQASPTPLPAGQVR
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GTR3_PONAB
Sequence: MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLIIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPTILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMEVNSIEPAKETTTNV
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: G3P1_STAAS
Sequence: MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH 1, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.