PharMolix/UniProtQA huggingface dataset:
Protein: IER5_MOUSE
Sequence: MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGPAGTPAVPPPQQPGEPVAGPPSGWGEPPPPVARAAWPEPEPQPQPQPQRPSVCHTPGAGSSEPVAAVAGSGEALRGGEEDSAAAAWGRVERPRAASSGGGSDACPEGPRAVRRPCGCPPAVEERSSEDGSPAPPAPCPRKRGAAGVGGGRASCSAPGSTPLKKPRRNSEEQPVTGEDDTDEEMETGNVANLISIFGSSFSGLLRKSPAGGREEEEAEEGGPEAAEPGQICCDKPVLRDMSPWSTAIVAF
What is the function of this protein?
Plays a role as a transcription factor.  Mediates positive transcriptional regulation of several chaperone gene during the heat shock response in a HSF1-dependent manner.  Mediates negative transcriptional regulation of CDC25B expression.  Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A.  Involved in the regulation of cell proliferation and resistance to thermal stress.  Involved in the cell cycle checkpoint and survival in response to ionizing radiation.  Associates with chromatin to the CDC25B promoter.
What are the official names of this protein?
Immediate early response gene 5 protein.
What is the protein family that this protein belongs to?
Belongs to the IER family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic. Translocated in the nucleus during heat shock.
Protein: NQRD_PROMH
Sequence: MADTKEIKRVLLGPLLDNNPIALQVLGVCSALAVTTKLETALVMTIAVTLVTAFSNFFISLIRNYIPGSVRIIVQMAIIASLVIVVDQVLQAYAYEISKQLSVFVGLIITNCIVMGRAEAYAMKSPPIESFMDGIGNGLGYGVILILVGFLRELFGSGKLFGITVMESIQNGGWYQPNGLFLLAPSAFFIIGLLIWGLRTLKPAQVEED
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR5_CLOB6
Sequence: MVSYKEAGVNIEEGYKSVDLIKKHASKTFTKGVLNNLGSFAGMFELPKYKNPVLVSGTDGVGTKLDIAFRMKKYNTVGIDCVAMCVNDILCHGAKPLFFLDYIACGKLEAEVAAQLVEGVSNGCIQSECALIGGETAEMPGFYRDGEYDIAGFAVGVAEKDEIIDGSKIEDGDVLIGIASSGPHSNGYSLIRKIVEDLHKDFAGDKIGNTLLTPTKIYVKPVMKLLEKYNIKGMAHVTGGGFYENIPRMFKEDFTAVINKKSYPVPNIFNHLMNLGVEEDHMYNTFNMGIGFVLCVNEKDGENIIKDLIEMGEKGYKIGYVKKGDKSVELI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_GRAFK
Sequence: MSSKVRVRFAPSPTGPLHIGGVRTALYNYLFAKKHGGDFVLRIEDTDQNRYVEGAEDYIIEALNWCGIPYDEGPGKEKGFGPYRQSERKDQYREYAEKLIKSGNAYYAFDTSDELDGHRKDHEEKGKTFIYNWHNRQKLKNSLSLSQEEVQEKLDGEEDYVIRFKSPQDETLHLKDVIRGDMEIDTNILDDKVLFKSDGMPTYHLANIVDDHLMEITHVIRGEEWLPSLALHYMLYRAFGWNAPQFAHLPLILKPQGKGKLSKRDGEKMGFPVFPLEWKDPESGDISAGYKEEGYFPEAVVNMLAFLGWNPGTEEEFFGLEDLTKAFELERVHKGGAKFDPEKTKWFQQHYIQLADNEFLADEFEKRLEKKEIEADKIYISEVVALIKERVVFVEDFWDQGYFFFIAPTSFDPKDSKKAWKEGTSELMTELNEYLKSIDNFEAEHLQETVKGWIKSKEIGFGKVMMPLRIALVGALQGPDLYKIAEFIGKEATLKRIQKAVDTLK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYS1_PONAB
Sequence: MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGANYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKLHVVAHFHEWLAGIGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQYLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKMLDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLSTPSEPLSPTSSLGEERN
What is the function of this protein?
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
What are the official names of this protein?
Glycogen [starch] synthase, muscle.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 3 family.
Protein: RBFA_POLAQ
Sequence: MHKTSPHRNQRLADQIQRDLAELIPRELRSTSLGLITLQSIELSPDLAHAKVFFTVLGAEPEHALKALQEKAGYLHSLLFKRLHIHTVPTLHFHYDSSVEHGIEMSRLIDQAVESDQQDESK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P34_SOYBN
Sequence: MGFLVLLLFSLLGLSSSSSISTHRSILDLDLTKFTTQKQVSSLFQLWKSEHGRVYHNHEEEAKRLEIFKNNSNYIRDMNANRKSPHSHRLGLNKFADITPQEFSKKYLQAPKDVSQQIKMANKKMKKEQYSCDHPPASWDWRKKGVITQVKYQGGCGRGWAFSATGAIEAAHAIATGDLVSLSEQELVDCVEESEGSYNGWQYQSFEWVLEHGGIATDDDYPYRAKEGRCKANKIQDKVTIDGYETLIMSDESTESETEQAFLSAILEQPISVSIDAKDFHLYTGGIYDGENCTSPYGINHFVLLVGYGSADGVDYWIAKNSWGFDWGEDGYIWIQRNTGNLLGVCGMNYFASYPTKEESETLVSARVKGHRRVDHSPL
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
P34 probable thiol protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole. Note=Protein storage vacuoles of seeds. This protein was wrongly thought to be associated with seed oil bodies.
Protein: P2B10_ARATH
Sequence: MGRKRRVKSESSPFDSFPEDCISYIISFTNPRDACVAATVSKTFESTVKSDIIWEKFLPADYESLIPPSRVFSSKKELYFSLCNDPVLFDDDKKSVWLEKASGKRCLMLSAMNLSIIWGDNPQYWQWIPIPESRFEKVAKLRDVCWFEIRGRTNTRVLSPRTRYSAYIVFKGVDKCYGFQNVAIEAAVGVVGQEPSRRLICFSEAIRRGRRNVVKPKQREDGWMEIELGEFFNDGGIMDNDEIEMSALETKQLNRKCGLIIQGIEIRPAKIL
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box protein PP2-B10, Protein PHLOEM PROTEIN 2-LIKE B10, AtPP2-B10.
Protein: TPM_PANBO
Sequence: MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANNRAEKSEEEVFGLQKKLQQLENDLDSVQEALLKANQHLEEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: GLYA_BACC3
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGLY1_CHICK
Sequence: MAGSAGLSSSPSSPAVRELCKNARDTFLEASRLLLTYADNILRNPYEEKYRSIRNGNPAFSTRLLPVRGAVECLFEMGFQEGETHMVFPKEASIEQLRKVRDLIAVERSSRLNESNQVHRSASSETVAITQAIAHQPSRPAGSVPTPDHQQPEPSLLQSLKMAADILTTLQSKCDHLILAYESTSLQQKALALIPLQQLKEKAQRKLAQATRLDKGEHVNEEDFLLLELLNWFKNDFFHWVDNLPCSRCGGQTEGKRDYLSPTDDDLRWNADRVENHYCSQCQFCNRFPRYNNPEKLLETRRGRCGEWANCFTLCCRAVGFEARYVRDWTDHVWTEVYSASQKRWLHCDPCENVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHQEVLTRRTALSEAKLRETINAINKKKQQSLSEGRRKELLERTIVELAEFISPKTPKPGEFGGRTSGSMAWRIARGETGSEERKEVIFIPSEKEKASKLFHLMYNVVEDSYTRISNNNEQITGWGTGIWKAESIARKVETDWKMVYLARKEGSSSASISWKFECKSVGLKIDNISIRTSSQTFHSGRIKWRLYSPTAEVILVGDNSLSSYSDFCGATEVTLEATLSGGDGKAAWQHTQLFRNSLAGCGENCLEMIIKLADL
What is the function of this protein?
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation.  Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp.  Prefers proteins containing high-mannose over those bearing complex type oligosaccharides.  Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins.  Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).
What are the official names of this protein?
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, PNGase, N-glycanase 1, Peptide:N-glycanase.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. PNGase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_CALBD
Sequence: MVYWIIIMSTFVLDQLTKARAEKFFVDSPVNLLGGILSLTYVQNRGGAFSILEGKRRFFIIVSIILILFLCYMIFKSTSNLYKFSFSLIVGGAIGNLFDRIVKGYVVDFIDIKVIPVFNLADFFITGGVLLLTFLILKEGGEELFLKKKP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CITX_ECOL5
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHAWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: RL19_STRE4
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFEGVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DNLJ_HELPG
Sequence: MIKSQKEYLERIAYLNTLSHHYYNLDESIVSDAVYDELYQELKAYEEKNPNDIQANSPTQKVGATATNSFNKNPHLMRMWSLDDVFNQSELQAWLQRILKTYPSASFVCSPKLDGVSLNLLYQHGKLVSATTRGNGLEGELVTNNAKHIANIPHFIAYDGEIEIRGEVIISKEDFDALNKERLNANEPLFANPRNAASGSLRQLDSEITKKRKLQFIPWGVGKHSLNFLSFKECLDFIVSLGFSAIQYLNLNKNHQEIEENYHTLIREREGFFALLDGMVIVVNELNIQKELGYTQKSPKFACAYKFPALEKHTKIVGVINQVGRSGAITPVALLEPVEIAGAMINRATLHNYSEIEKKNIMLNDKVVVIRSGDVIPKIIKPLETYRDGSQQKIMRPKVCPICSHELLCEEIFTYCQNLNCPARLKESLIHFASKDALNIQGLGDKVIEQLFEEKLIVNALDLYALKLEDLMRLDKFKIKKAQNLLDAIQKSKNPPLWRLINALGIEHIGKGASKTLAKYGLNVLEKSEAEFLEMEGFGVEMVRSLVNFYASNQEFIRSLFELLNPKNSDMAEEKQESSSVFNNKTIVLTGTLSKPRQEYAQMLENLGAKITSSVSAKTDFLIVGENAGSKLALAKKHGVSVLNEEELLKRLKKLDQN
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL30_BLOFL
Sequence: MLKITQIRSSIGCIPKHKATLRGLGLRRIGNTVSKIDTPSVRGMINLVLYMIQVKRQD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MUTL_BRUA2
Sequence: MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: XYLA_BRUME
Sequence: MSTGFFGDIQKVRYEGPESDNPLAFRHYNADEIVLGKRMEDHLRFAVAYWHSFAWEGGDPFGGRTFDRPWFSNEIDAAKLKADVAFEFFSLLGAPYYCFHDADVRPEGRNFAENTRYLNEIVDIFEKKQAETGMKLLWGTANLFSNRRYMAGAATNPDPDVFAFAAATVKTCIDATKRLGGENYVLWGGREGYETLLNTDLSRELDHMGRFLSLVVEYKHKIGFKGTILIEPKPQEPTKHQYDYDVATVYGFLKRYGLENEVKVNIEQGHAILAGHSFEHELALARTLGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYQVLLAGGFTTGGTNFDAKLRRQSLDPQDLLIGHIGGMDCCARGLKAAARMLEDGALSKPLDERYAGWNGEFGKRLLSGLSLDQIAGEVEAKDINPQPKSGRQEYLENIVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAV_CLOBE
Sequence: MKIVYWSGTGNTEKMAELIAKGIIESGKDVNTINVSDVNIDELLNEDILILGCSAMGDEVLEESEFEPFIEEISTKISGKKVALFGSYGWGDGKWMRDFEERMNGYGCVVVETPLIVQNEPDEAEQDCIEFGKKIANI
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: TRI72_RABIT
Sequence: MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLSRVAGEPAADGTVNCPCCQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRVLVCGVCASLGSHRGHRLLPAAEAHSRLKTQLPQQKLQLQEASMRKEKSVAVLEHQLTEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDREAERVRSEAGVALRRELGGLHSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPSLVVSPTGRRVECSEQKAPPAGDDARQFDKAVAVVAQQLLSDGEHYWEVEVGDKPRWALGVMASEASRRGRLHAVPSQGLWLLGLRDGKTLEAHVEAKEPRALRTPERRPTRLGLYLSFGDGVLAFYDASDADALELLFAFRERLPGPVYPFFDVCWHDKGKNAQPLLLVGPDGQEA
What is the function of this protein?
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites.  Specifically binds phosphatidylserine.  Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site.  This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation.  Probably acts upstream of the Ca(2+)-dependent membrane resealing process.  Required for transport of DYSF to sites of cell injury during repair patch formation.  Regulates membrane budding and exocytosis.  May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 72, Mitsugumin-53, Mg53.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma. Cytoplasmic vesicle membrane. Note=Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine.
Protein: RNFT2_MOUSE
Sequence: MWLLAAHQVLRKMQRRHSSNTDNIPPERSRSQALSPEASVDEGGVFESLKAETASPPALFSGLAGGLPASPFPAGLVLGSTAGGGDVFIPMPATRDEAGGRSAEGSTYHHRQAHHHFHHGAHRGGSLLQHVGGDHRGHSEEGVDEQPGTPAPALSELKAVISWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTMYVLYTFSSQQLYSSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIVLYSLCKSFDICGRVGGLRKALKLLCTSQNYGVRATGQQCTEAGAVCAICQAEFRDPMILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHLQVY
What are the official names of this protein?
RING finger and transmembrane domain-containing protein 2, Transmembrane protein 118.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEF3_SHEON
Sequence: MAVLDILTIPDERLKRKAQPVKDIEAIQGFIDDLIETMYHTDDGIGLASTQVGSTDAVIVIDLSETRDQPLVLVNPEIVEKSGEYVGEEGCLSIPGYRAKVTRFEKVKVTALDRQGKAIEIETDDFLAIVLQHEIDHLHGKVFIEHLSTLKQQIALKKVRKYA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 3, PDF 3, Polypeptide deformylase 3.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: AMYP_STRCA
Sequence: QYNPNTQPGRTSIVHLFEWRWADIALECERYLAPYGFGGVQVSPPNENVIITNPYRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVKNHMCGSGAGSGTHSTCGAYFNAGNRDSPAVPYSGWDFNDGKCRTGSGEIENYGDASQVRDCRLVGLLDLALEKDYVRSTVAGYMNHLIDIGVAGFRLDAAKHMWPGDIKAFLDKLHNLNTNWFSSGSRPFIYQEVIDLGGEPITSSQYFGNHRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSFRWPRHFENGKDVNDWYGPPSNSDGSTKEVTINADSTCGNDWVCEHRWRQIRNMVIFRNVVDGEPFSNWWDNNSNQVAFGRGSKGFIVFNNDDWHMNVDLYTGLPAGTYCDVISGQKEGSRCTGIQVYVSGNGKANFQISNNAEDPFIAIHVGAKL
What are the official names of this protein?
Pancreatic alpha-amylase, PA, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RS26A_SCHPO
Sequence: MTQKRRNCGRNKHGRGHTKFVRCINCSRAVPKDKAIKRWNIRNMVETAAIRDLSEASVYSEYAIPKIYVKLQYCVSCAIHARVVRVRSREGRRIRTPPPRVRYNRDGKRVNPAAIAKTAL
What are the official names of this protein?
40S ribosomal protein S26-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS26 family.
Protein: RL31_BRUA1
Sequence: MKANIHPDYHTIKVVMTDGTEYMTRSTWGKEGDTMNLDIDPTTHPAWTGGSQTLLDRGGRVTKFKNRFGNLGI
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PYRF_LIGS1
Sequence: MKYDRPIIALDFPDKEKTFEFLKKFPEDEKLFVKVGMELFYSEGSDMVKELISEGHDVFLDLKLHDIPNTVKQAMKVIGKLGVKLTTVHISGGSEMLIAAKEGLLDGANGDTNTKILGITQLTSTDEEMVKNEQKLSISLKESVKNYAKIAQKSGLDGVVCSAEESDMIYKLTGDDFLRITPGIRLAGGDVGDQKRVMTPDAAARNHSSGIVVGRAITKAENPLDSYRLVTKLWREK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CCA_BACCR
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRNVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGKMVDLFAGQEAIQQREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLEMKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKGLKELVETKLFSHLPYLQMSEERLLKATQYKWDSFETDIEAWAFFLYCIGEEHPSVFLRQWKFSNKKIKDIVAVLLTIRTRKEKDWDTVLLYKTGIHIAEMAERVYEAMIERYDPTSVERVQSMFHALPIQERQEMNVTGNDLLNWANKKPGPWVAEMLQKIEEAIVQGNVVNEKERIREWLQGCNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: RS3_STRPM
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINKELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINIIEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HIS7_SULDN
Sequence: MISKSRKTKETDITVSLDINGNGKSKIDTGVGFLDHMLDSFSKHSLIDLEITCKGDTHIDDHHSVEDIGIVLGALFAEALYPVSNMERFGSANIVMDEACVSCDLDLSNRPYLVYEVNLAGKVGQFDTELVEEFFRAFVLNARISTHIVLQRGKNRHHIIEAAFKAVAVALRRAMQKNERVGIPSTKDML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.