PharMolix/UniProtQA huggingface dataset:
Protein: PIK1_CAEEL
Sequence: MDDSLGVSEVVMIPFMKREVLQQICAILDTDNTWETIAPYMPGIELRDVEGCKRYSSYNQSPSELLLRIWSSKGYSTTHLYQLFAKTKLIRLMRMMRSQVHEKYHYLENKVTNSTSRVSKQMVQPPGSQSASRLKKTEIKESSPSPAAAAASQLSRSNTDDTLRVAIEGTLPVTYCELLEATNGFAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNGSLEDRLLCRKGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFITSKILTTKLDVYSFGIVLLEIASGQRAYSDSRETRGLVEYCQVNKELAAHRKIPVREIFIDRRAPPLVGDEEKSFLDALIEVGLAGANNDRKVRPTMSQIVEYLCKNSIPPVV
What is the function of this protein?
Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input.
What are the official names of this protein?
Pelle-like serine/threonine-protein kinase pik-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Protein: VITH1_ARATH
Sequence: MESHNVSNSLNLDMEMDQEKAFDYSKRAQWLRAAVLGANDGLVSTASLMMGVGAVKQDVKVMILSGFAGLVAGACSMAIGEFVSVYSQYDIEVAQMKRENGGQVEKEKLPSPMQAAAASALAFSLGAIVPLMAAAFVKDYHVRIGAIVAAVTLALVMFGWLGAVLGKAPVFKSSARVLIGGWLAMAVTFGLTKLIGTHSL
What is the function of this protein?
Probable vacuolar iron transporter involved in the transfer of iron ions from the cytosol to the vacuole for intracellular iron storage (PubMed:25360591).  Involved in regulation of cellular iron homeostasis (PubMed:25360591).  Vacuolar iron storage is required for seed embryo and seedling development (PubMed:25360591).
What are the official names of this protein?
Vacuolar iron transporter homolog 1, Protein NODULIN-LIKE 1, Vacuolar iron transporter-like 1, AtVTL1.
What is the protein family that this protein belongs to?
Belongs to the CCC1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: CA220_HUMAN
Sequence: MIPVRGLWYCYLQVKKVRLREAERLGPKSQCPAECGAASWISWVLQHQQLLASEWATKDGRGTWGSKPSCTVPALSATSQLLQLGRLNSDLQFVRQRAKKSVSSPSLLQFWCCLSRLSFHALNQKINSTNINIT
What are the official names of this protein?
Putative uncharacterized protein C1orf220.
Protein: Y278_HAEIN
Sequence: MNAKILVIKVGQVETLTFSDGSQYESAIRKKVVPSVKIHSLGAEGNDVGLKKHHGGVDKALFFMSADSFNELNALLXIKIFPYMDTATYGENFVVSGLNEDNVCIGDRYQIGSTILEVSQPRKPCERLSKNTENEETRDIVYQTGLSGWYVRIIETGTIKQKDELKLLARPYPQITIRHLNRLLSTPKNEAELDSALEIEVLAEAFKRSIRSQISKFKQQG
What are the official names of this protein?
Uncharacterized protein HI_0278.
Protein: ARNE_PSEPF
Sequence: MSLWLLLLACLLTCLGQVAQKCAVENWRGADLSWSRKWRSPWLWLALFALGSGLLVWLLVLQRLPVSVAYPMLSLNFVIITLIARFVFKEPVDVQHWFGVLLVIGGVALLGQQS
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPB_ECOLC
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPA_LARHH
Sequence: MLTGSLVAIVTPMLEDGSVDFEALDRLVDFHIESGTSGIVAVGTTGESAALAVEEHLQVVAAVVKRAAGRIKVIAGAGANSTHEAIDLTRESRRLGADQVLSVVPYYNKPTQEGMYRHFRAIAESTDIPVILYNVPGRTVADMCNDTVLRLAEIPNIIGLKDATADLARCCDLVKRAPKDFALYTGDDATAMAFMLCGGHGVISVTANVAPRQMAELCRAAIAGDVQAARRINDPLQGLHKDLFCEANPIPVKWALERMGRIPAGIRLPLTRLSDAGQSKVEAALKAANLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUPP_BOMMO
Sequence: MKSMIVVACLALACGAHASGWAGPPANIALSQDGRNILDTPEVAQARAAHISALQQASKNNPNPNDDGSYDPRWDNEEYWQQAEGKWNGAPAPAWNAAPAPSWNGAHAAAPSWNAAPAHSWNAAGSAPAPVAETPEVAQARAAHLAALSAAKSAAPAQQQWNAPAHQDWNAPAHQDWNAPAHQDWNAPAHQSWNGAPSWQSGAPAHQPANIRLANDGSGILDTPEVAAARAAHLAAHAQAAHSAPAHAPQQHW
What is the function of this protein?
Component of the cuticle of the pupae of silk moth.
What are the official names of this protein?
Pupal cuticle protein.
Protein: DHYS_ENCCU
Sequence: MDRPQNVKDLARKVKDNLSFSREVRGMDFEKEWDFMAIMRSFETMGFQGSNLYRAVEEIERMKNSKIFFGCTSNIISSGLRDVIATLVKRRHVHVLVITGGGIEEDIIKAFKPTFCADFRLDGAELRDNGLNRIGNLVIPSENYEHLESWLNNIVNDITEGYTAERPRILTPSSFIRILGERIDDESSILYWAAKNDIPVYSPAVVDGSLGDILSFHPRRKMLKLDIVEDVYRINCETIFCGETAAIILGCGVVKHHILNANLFKNGLEHCVLINNAQEFDGSDAGASLDEAVSWGKVKPGTRGVKVFGDATILFPLLVGATFMRKDKDVPKGE
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: HIS4_DESVM
Sequence: MILFPAVDIKDGRCVRLRQGRADAETVFSDDPAAMARHWQDQGAKWLHVIDLDGAFSGMPANFELIRRICADLSVPVQLGGGIRDEATAKAYLDAGVERLIIGTVALEEPDLYARLCATFPGRIGVSLDAEGGRLKTKGWVADSGLTVDDVLPRLLAAGTAFVIYTDIDRDGMQTGVNLSALERLAGMCPVPVIAAGGVATLEDVRALYPMTLTSSVEGAITGRAIYTGTLDLHAAMEWIAAQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAST_DROME
Sequence: MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI
What is the function of this protein?
ATP-dependent microtubule severing protein.  Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle (PubMed:15242610, PubMed:15562320, PubMed:15823537, PubMed:16276413, PubMed:17452528, PubMed:25875445, PubMed:18202664, PubMed:19341724).  Regulates microtubule stability in the neuromuscular junction synapse (PubMed:15242610, PubMed:15562320, PubMed:19341724).  Involved in lipid metabolism by regulating the size and distribution of lipid droplets (PubMed:25875445).  Involved in axon regeneration by regulating microtubule severing (PubMed:23122959).
What are the official names of this protein?
Spastin, D-Spastin, Dm-Spastin, Dspastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome. Lipid droplet. Note=Forms a intramembrane hairpin-like structure in the membrane (By similarity). Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules (PubMed:17452528). Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles (PubMed:15823537).
Protein: Y3293_ARATH
Sequence: MASKIKNGLSDTTLRKSSSTSLRVPRLTRIVTKPDSNSPSPTQQQSRLSFERPSSNSKPSTDKRSPKAPTPPEKTQIRAVRVSESQPQSVQIKEDLKKANELIASLENEKAKALDQLKEARKEAEEASEKLDEALEAQKKSLENFEIEKFEVVEAGIEAVQRKEEELKKELENVKNQHASESATLLLVTQELENVNQELANAKDAKSKALCRADDASKMAAIHAEKVEILSSELIRLKALLDSTREKEIISKNEIALKLGAEIVDLKRDLENARSLEAKVKELEMIIEQLNVDLEAAKMAESYAHGFADEWQNKAKELEKRLEEANKLEKCASVSLVSVTKQLEVSNSRLHDMESEITDLKEKIELLEMTVASQKVDLEKSEQKLGIAEEESSKSEKEAEKLKNELETVNEEKTQALKKEQDATSSVQRLLEEKKKILSELESSKEEEEKSKKAMESLASALHEVSSESRELKEKLLSRGDQNYETQIEDLKLVIKATNNKYENMLDEARHEIDVLVNAVEQTKKQFESAMVDWEMREAGLVNHVKEFDEEVSSMGKEMNRLGNLVKRTKEEADASWEKESQMRDCLKEVEDEVIYLQETLREAKAETLKLKGKMLDKETEFQSIVHENDELRVKQDDSLKKIKELSELLEEALAKKHIEENGELSESEKDYDLLPKVVEFSEENGYRSAEEKSSKVETLDGMNMKLEEDTEKKEKKERSPEDETVEVEFKMWESCQIEKKEVFHKESAKEEEEDLNVVDQSQKTSPVNGLTGEDELLKEKEKKKKKTLFGKVGNLLKKKGPVNQK
What are the official names of this protein?
WEB family protein At3g02930, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the WEB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDUA9_PONPY
Sequence: MAAAAQSRVVRVLSMSRSAITAIATSVCHGPPRRQLHHALIPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDTYDIMHLRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETRNFDFEDVFVKIPQAIAQLSKEAGVEKFIHVSHLNANIKSSSRYLRNKAVGEKVVRDAFPEAIIIKPSDIFGREDRFLNSFASMHRFGPTPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPNRYLLFHLVKYIFAVAHRLFLPFPLPLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRWLSAEIEDVKPAKTVNI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial, Complex I-39kD, CI-39kD, NADH-ubiquinone oxidoreductase 39 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA9 subunit family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MSRB_ENTFA
Sequence: MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RL15_ACIB3
Sequence: MTLRLNELAPAEGAKREHRRLGRGIGSGVGKTGGRGIKGQKSRKSGGVRPGFEGGQTAIYRRLPKFGFTSQIALKTAEVRLSELSKVEGDIVSLETLKAANVVRRDQIRARIVLSGEITRAFTVQGVALTKGAKAAIEAAGGKVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RSMA_MYCPU
Sequence: MRAKKRFGQNFLIDQNIINKIVDSSEVENRNIIEIGPGKGALTKILVKKANKVLAYEIDQDMVNILNQQISSKNFVLINKDFLKEEFDKSQNYNIVANIPYYITSDIIFKIIENHQIFDQATLMVQKEVALRILAKQNDSEFSKLSLSVQFFFDVFLICDVSKNSFRPIPKVDSAVIKLVKKKNKDFSLWKEYFEFLKIAFSSRRKTLLNNLKYFFNEQKILKFFELKNYDPKVRAQNIKNEDFYALFLELR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PSEPF
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQMRMAASRPYAERIRQVIGHLANANPEYRHPFMIDREVKRVGYVVVSSDRGLCGGLNTNLFKALVKDMAVNRENGVEIDLCVVGSKGAAFFRNFGGNVVAAISHLGEEPSINDLIGSVKVMLDAYLDGRIDRLSVVSNKFINTMTQQPTVEQLIPLVATPDQELKHHWDYLYEPDAKELLDGLMVRYVESQVYQAVVENNAAEQAARMIAMKNATDNAGDLISDLQLIYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAA40_DANRE
Sequence: MGRKSNRAKEKKQRRLEERAAMDAVCAKVDAANKLEDPLSAMPVFKKYDRNGLNLQIECKRVTALSPDTVEWAYELTRANMQTLYEQSEWGWKEREKREEMKDERAWYLLARDADSTPLAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLIANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDETSPSMSGCCGEDCSYEILSRRTKYGEVSGHAHGGHCGGCCH
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A.  In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'.
What are the official names of this protein?
N-alpha-acetyltransferase 40, N-acetyltransferase 11, N-alpha-acetyltransferase D, NatD.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA40 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH601_METCA
Sequence: MAAKEVKFSDDARTRMLRGVNILAHAVKVTLGPKGRNVVLEKSFGAPTVTKDGVSVAKEIELSDKFENMGAQMVKEVASQTSDVAGDGTTTATVLAQSILTEGLKAVAAGMNPMDLKRGIDKAVAAAVDEIHAMSVPCTDSNAIAQVGTISANADESIGKIIAEAMDKVGKEGVITVEDGSGLENQLDIVEGMQFDRGYLSPYFINNQQSMSAELENPFILINEKKISNIRELLPVLEGVAKAGRPLVIVAEDVEGEALATLVVNNMRGILKVAAVKAPGFGDRRKAMLEDIAVLTGGTVISEDIGLSLEKATLADLGTAKKVQITKENTTIIDGAGSSEAIQGRVAQIRKQIEDTTSDYDREKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALIRALAKLRDLKGANHDQDVGISIARRAMEEPLRQIVANAGDEPSVVLNKVAEGAGNFGYNAATGEYGDMVAMGILDPAKVTRSALQNAASVASLMITTEAMVAEEPKEEAPMPGGMGGMGGMGDMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STAA3
Sequence: MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAB2_YEAST
Sequence: MSQEQYTENLKVIVAEKLAGIPNFNEDIKYVAEYIVLLIVNGGTVESVVDELASLFDSVSRDTLANVVQTAFFALEALQQGESAENIVSKIRMMNAQSLGQSDIAQQQQQQQQQQQPDIAQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQLQPLQPQLGTQNAMQTDAPATPSPISAFSGVVNAAAPPQFAPVDNSQRFTQRGGGAVGKNRRGGRGGNRGGRNNNSTRFNPLAKALGMAGESNMNFTPTKKEGRCRLFPHCPLGRSCPHAHPTKVCNEYPNCPKPPGTCEFLHPNEDEELMKEMERTREEFQKRKADLLAAKRKPVQTGIVLCKFGALCSNPSCPFGHPTPANEDAKVIDLMWCDKNLTCDNPECRKAHSSLSKIKEVKPISQKKAAPPPVEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLPEKKGAAPNSNVPTNERPFALPENAIIENAPPQTSFTHQEQDTEMN
What is the function of this protein?
Essential protein that binds to polyadenylated RNA and single-stranded DNA (PubMed:8474438).  It may be involved not only in RNA processing but also in transcription regulation.  Associates directly with nascent RNA polymerase II transcripts and remain associated during subsequent nuclear RNA processing reactions (Probable).  Involved in mRNA poly(A) tail length control and nuclear export (PubMed:11927564, PubMed:11779864).  Functions in surveillance and the packaging leading to generation of export-competent mRNPs.  Controls both mRNP compaction that facilitates movement through nuclear pore complexes and the length of transcript poly(A) tails (PubMed:19840948, PubMed:22560733).
What are the official names of this protein?
Nuclear polyadenylated RNA-binding protein NAB2.
What is the protein family that this protein belongs to?
Belongs to the NAB2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the nucleus at steady- state, it shuttles between nucleus and cytoplasm.
Protein: SPEE_YERP3
Sequence: MSQKELWYETLHANFGQYFSVENVLYREKTEHQDLVIFENPELGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQITMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPIGPGESLFTSVFYEGCARSLNEGGIFVAQNGVCFLQQDEAVNSHNKLSHYFSDVSFYQAAIPTYYGGIMTFAWATQNPALRQLDLATLQNRFAQAGLACRYYNPAIHVGSFALPQYLLDALTTIPKVIGVDSSE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_LIMRD
Sequence: MDKRPIGVMDSGLGGLSVIRVLREQLPQESVIFVGDQGHFPYGTKTKEQIQQLALRIGKFLLEQDVKMMIIACNTATAAALRLLQNELPIPVIGVIKPGAMAATQHHYKKIGVIGTESTIKNGAYAKTLAKLNPDLSVISSPAQPLVSIVEHGQTGTSEAQKAVDTELEVFDNQSIEALILGCTHFPFLQKEIHNKLGSNVQLIDPAFETIRQAKELLTGKNQLSDNLASSINLYSTGDAKDLVAGAQQWLPNGYSKCAHIELNEEG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: UDGA_THET8
Sequence: MTLELLQAQAQNCTACRLMEGRTRVVFGEGNPDAKLMIVGEGPGEEEDKTGRPFVGKAGQLLNRILEAAGIPREEVYITNIVKCRPPQNRAPLPDEAKICTDKWLLKQIELIAPQIIVPLGAVAAEFFLGEKVSITKVRGKWYEWHGIKVFPMFHPAYLLRNPSRAPGSPKHLTWLDIQEVKRALDALPPKERRPVKAVSQEPLF
What is the function of this protein?
Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP.  Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair as well as from single-stranded DNA (PubMed:12000829, PubMed:14556741).  Specifically recognizes uracil that is flipped out from double-stranded DNA (PubMed:14556741).
What are the official names of this protein?
Type-4 uracil-DNA glycosylase, TTUDGA, TthUDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
Protein: NADK_PYRFU
Sequence: MKFGIVARRDKEEALKLAYRVYDFLKVSGYDVVVDKDTYEHFPYFNERDVIPLEEFDVDFIIAIGGDGTILRIEHMTKKDIPILSVNMGTLGFLTEVEPSDTFFALSRLIEGEYYIDERIKVRTYINGENRVPDALNEVAILTGIPGKIIHLKYYVDGGLADEVRADGLVVSTPTGSTGYAMSAGGPFVDPRLDVILVVPLLPLPKTSVPMVIPGSSRVDITLVSDREIILAIDGQYYEYLPPDVEITVVKSPRKTKFVRFTKEIYPKYTMKIKERH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_SYNFM
Sequence: MSTTCAIVPAAGRGLRMGRDRPKQFLEIAGRSILLHTLDALAAAPFLAQTYLLVPEDFQDEARGLVCGHPSVTVVAGGAERQDSVLNGLRSLPDECGWVLIHDGVRPFVSSALLEAAWKTAQRTGAAIAAVPATDTVKRGQGGTVVETLNREEIWLVQTPQVFRRDIIASAYEAAVQRGWVGTDDASFVERLNLPVSVVLGERTNVKVTTPEDLDWAQWFLLRSGGLAGRISGRE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: GSTMU_CRILO
Sequence: MPMILGYWNVRGLTNPIRLLLEYTDSSYEEKKYTMGDAPDSDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYIARKHNLCGETEEERIRVDIVENQAMDTRMQLIMLCYNPDFEKQKPEFLKTIPEKMKMYSEFLGKRPWFAGDKVTLCGFLAYDVLDQYQMFEPKCLDPFPNLKDFLARFEGLKKISAYMKTSRFLRRPIFSKMAQWSNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase Y1, Chain 3, GST class-mu.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTB_SALPB
Sequence: MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.