PharMolix/UniProtQA huggingface dataset:
Protein: MNMC_SALAR
Sequence: MKQYAIQPATLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNRLAERFPVHSHPLFIVAESGFGTGLNFLTLWQAFNNFRSEHPQATLQRLHFVSFEKFPLTRDDLALTHQHWPELAPWAEQLQAQWPLPLAGCHRLLLDQGRVTLDLWFGDINELTDQLDATLNQKVDAWFLDGFAPAKNPDMWTPNLFNTMARLARPGATLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMERCLTPTISAPWFYRSGSEKRETAIIGGGIASALLSLALLRRGWQVTLYCADDKPARGASGNQQGALYPLLSKHDAAINRFFPTAFTFARRLYDALPVSFDHDWCGVTQLGWDEKSQQKIARMLSLALPAGLASALNAEETTQAVGVTTRCGGITYPAGGWLCPEQLTRAVIALATEQGLQTRFRHTLTSLAAQKSQWQLRFASGEAASHDTVVLANGHQINRFDQTQPLPVYAVGGQVSHIPTTPALSALRQVLCYDGYLTPQNPNNRQHCIGASYHRGNESTVWREEDQRQNRQRLLDCFPDADWAKEVDVSDNSARCGVRCATRDHLPMVGNVPDYHATLTHYADLADNKASAVPAPVYPGLFMLGALGSRGLCSAPLCAEILAAQMSNEPIPLDASTLAALNPNRLWVRKLLKGKAVK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_LISMH
Sequence: MTFNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDREINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVIDGKSERGGFPVFRKPMRQWMLKITAYADRLLDDLDLVDWPENIKDMQRNWIGRSEGAEVTFKIKDSDETFNVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKTGVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQRYWGEPIPVIHWEDGETTLVPEDELPLLLPKATEIKPSGTGESPLANLHDWVNVTDENGRKGRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLFNQGMILGENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDRIWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKQDTIPKQYVEGFVQLLSPIAPHLAEELWEILGHTETISYVAWPTYDETKLVEDEVEIVLQVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SYMTH
Sequence: MSRIGKAPIEIPAGVEVTVEGNLVRVKGPKGELSREIHPAMSITIENGALRVSRPSDEREHKALHGLTRTLIANMVEGVTKGYSKTLELVGTGYRAAKTGNQLTLSVGYSHPVVFNPPPGIEFQVPAPNQVIVAGIDKQLVGQVAADIRATRPPEPYLGKGIKYAGEHIRRKVGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PRS45_MOUSE
Sequence: MATSLRGLDAGPGSLRRWILICFAALLLLPPRPNLGYNENYTEPVCGTPWWPDNLEESHHWPWEASLQIEDKHVCGGALIDRSWVVSAAHCIQGNKEYSVMLGSSTLHPNGSSWTLKIPVGDIIIHPKYWGRNFIRSDIALLCLETPVTFNKYVQPICLPEHNFNFKVGTKCWVTGWGQVKQHSSAQLTPAPELWEAEVFIIDNKNCDSIFHKKTLYPQVVPLIRKNMICTTNYGEDLCYGDPGGPLACEIDGRWILAGVFSWEKACATVPNLSVYTRITKYTIWIKDQVSHGAQLGPCRTSWLLLLPWLLQLPVSL
What are the official names of this protein?
Inactive serine protease 45, Inactive testis serine protease 5, Trypsin-like protease p98.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MEF2A_HUMAN
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
What is the function of this protein?
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes.  Also involved in the activation of numerous growth factor- and stress-induced genes.  Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.  Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.  In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.  Associates with chromatin to the ZNF16 promoter.
What are the official names of this protein?
Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
Protein: Y1150_BACCR
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMSIVKTATGSMHMWYGLKMLAGILVIGGMEMVLVKMSKNKPTGAVWGLFIVALVAVFYLGLKLPIGWKVF
What are the official names of this protein?
UPF0344 protein BC_1150.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FBIA_MYCTA
Sequence: MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
What is the function of this protein?
Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
What are the official names of this protein?
Phosphoenolpyruvate transferase, EPPG:FO PEP transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: SYFA_LACH4
Sequence: MDLFDKLKELHEQGLAEIKKATDEQTLNKIRVELVGRKGELTKILHSMRDVAPENRREVGQKVNELRDLFNKQLDTTKAKIVKAVLAKKLEDEKIDVTLPGREGHLGSKHPINIILDDLESYFIGMGYKVVQGPEIETDHYCFEMMNLPKDHPARDMQATFYIDGEDLLRTQTSGDQARVLEKHDFSKSPLKMVGPGKVYRRDDDDATHSHQFMQMEGLVVDKNVTMSDLKGTLEMIAKHVFGQDRATRLRPSYFPFTEPSVEMDVSCFNCDGKGCPICKYTGWIEVLGAGMVHPNVLENAGVDSTVYGGFAFGLGLDRFAILKYGIDDIRDFYTNDVRFLKQFRKEEN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SALSV
Sequence: MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ORF5A_EAVBU
Sequence: MFFYDWYVGLNDVIYDCIAILALGCAITCLLLILHRSALHRLHLVYADGSRRYCQFAAI
What are the official names of this protein?
Protein ORF5a.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: RL332_STAAC
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL9_LACLA
Sequence: MKVVFLEDVKGQGKKGQIKEVPTGYAQNFLIKKNLAKVATAAALSEVKGQAKAKEKEEAELLAEAKALKEVLEKEDTVVEIKMKVGQTGHTFGAVDKADIAKALKSQFNLKLDKRKIQLINKIQALGTKDVPVKLHRDVTAVVKVKISEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YIDC_TROWT
Sequence: MFDGLFDFLQNILLPIKWVIEQILVFFHTLLGFLGFGDKSGLSWALSIVGLVIVIRATLIPVFLKQIRAQRKMLEIAPEVRRIQEKYKGKRDVLSRQSMNQEMMEIYRVRGANPLSSCLPIVLQMPVFFGLYQVIESAQNAGTGVGPLNGPLGMDFRDSRIFGVVPLHDSFSHDFYALQAGQAFNLITMIVAGVLTAIMIAVQLFTQLKVIPKNIPENAKNTSVYKNQKVMLYLLPIMFLGMGFSFPVGILIYWTASNVWSAVQQAVAIYRNPSPGSLAFELRRKRLGVQNKKTKGQRQQPVNKRRAKRR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PETG_SORBI
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MTGA_VIBPA
Sequence: MLKRLKSFLFKMVLILLIAPIVLVGVVKYVDPPIWGWKLSRIVAPPKNYPDSSQHEWVSLTRISKNMQLAVIATEDQKFPHHYGVDFESLFDVISEAGDHGPSRGASTITQQAAKNVFLFPSHSYVRKAYELYFALLMELMWSKERILEVYLNVVEFGPGIYGAEAAAQNYFGVSAKQLSKWQAARLAVVLPNPYRIKVYPQSDYTARRTRWAMNQMSNLGSVQL
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ZHD7_ARATH
Sequence: MELGGKCNAITTTTMISTEVKPHTDPEPEAKPESDPSMALFPIKKENQKPKTRVDQGAKYRECQKNHAASTGGHVVDGCCEFMAGGEEGTLGALKCAACNCHRSFHRKEVYGHRNSKQDHQLMITPAFYSSNSSYKPRVMHPTGEIGRRTSSSSEDMKKILSHRNQNVDGKSLMMMMMRKKKRVRTKINEEQKEKMKEFAERLGWRMQKKDEEEIDKFCRMVNLRRQVFKVWMHNNKQAMKRNNSNISE
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Zinc-finger homeodomain protein 7, AtZHD7, Homeobox protein 28, AtHB-28.
What are the subcellular locations of this protein?
Nucleus. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Protein: SOX5_XENTR
Sequence: MLTDPDLPPEFERMSSKRPASPYGEADGEVAMVTSRQKMEDDGGDGLPAFHLPLHVGFKPHSEEFQAVSLLTQEGCDRRSPSYQHNTMELDCNKMPPFALHNAATSPIKAEELGRQSGESLANAMLGTPERRKGSLADVVDTLKQRKMEELIKSEPEETPSIEKLLSKDWKDKLLAMGSGNLGDVKGTPESLAEKERQLMAMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAAAQQGFLIPPGFSYKPGCSDPYPVQLIPTTMAAAAAATPGLAPLQLQQLYAAQLAAMQVSPGAKLPGVPPSNLSNAVSPSSIHTDKSTSSPPPKTKDDVTQPLNLSAKPKGSDSKSPSSPTSPHIPRLSSALAHKPICSTSASTPLRVNSIDILSSITSPGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVVNSLGLNNCRTDKDKSSLESLTQQLTGKPNEDKFSHAMMDFNLSGDSDGSAGISESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRSRRQQAQIPISTAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGIKEEEPHIKEEIHREDINGEMYDEYDEDDDPDVDYASDSENLSAEQAN
What is the function of this protein?
Transcription factor involved in chondrocytes differentiation and cartilage formation.  Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis.  Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: sox5 and sox6 cooperatively bind with sox9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate sox9's ability to transactivate.  Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes.
What are the official names of this protein?
Transcription factor Sox-5, SRY (sex determining region Y)-box 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: VL2_HPV26
Sequence: MVAVRAPRRKRASATDLYKTCKAAGTCPPDVIPKIEGSTLADKILQWSGLGIFLGGLGIGTGTGSGGRTGYIPLGGGGRPSVVDIGPTRPPIIIEPVGPTEPSIVTLVEESSIIQSGAPIPTFSGGNGFELTTSSATTPAVLDITPSAGTVHVTSTNIQNPLYIEPPIDIPQAGEASGHIFTTTSTAGTHSYEEIPMEVFASTNGTGLEPISSTPIPGIQRVSAPRLYSKAYQQVKVTDPNFIGNPSTFVTFDNPAYEPIDETLTYASSSTVAPDPDFLDIIALHRPALTSRKGTVRYSRLGQKATMKTRSGKQIGATVHYYHDISPIQSFAEHEEIELQPLHTSTHSSAPLFDIYADPDTVPSIHTPRMSYSPTTLPVPRYASNVFSSINTSTTNVTVPLSTSFELPVYSGSDIYTPTSSPTWPSLPPPPTTNLPAIVVHGDNYYLWPYIYLIHKRRKRMPYFFSDGFVAY
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: CYB_PUMCO
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGMYYGSYTFSETWNIGIMLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGITSDSDKIPFHPYYTTKDILGLLALILTLMLLVLFLPDMLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAMIPTLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASVLYFSTLLILMPISGIIENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HES1B_XENLA
Sequence: MPADVMEKNSSSPVAATPASVSNTPDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRVQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTDVRTRLLGHLANCVNQIHAMNYPAQPQIPSAAAPHPAYGQPMVQLPAAAPQSSPAPIACKMGGPPVEAAKVYGGFQLVPASDGQFAFLITNPAFPQNGSVIPLYTNSNVGTALPPSVSPSVMPSVTADSVWRPW
What is the function of this protein?
Transcriptional repressor of a subset of early mesodermal genes including myod1 and t/bra.  Binds DNA on N-box motifs: 5'-CACNAG-3'.  Acts as a negative regulator of myogenesis, mediating Notch signaling to repress expression of myod1 (By similarity).
What are the official names of this protein?
Transcription factor HES-1-B, Hairy and enhancer of split 1-B.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMT_FRAP2
Sequence: MKKLNIVFAGTPDISAQVLKDLYQSQHNIQAVLTQPDRAKGRGKKIQFSPVKEVAIANNTLVLQPLSFKKDPQVLEQIRELKPDVIVVIAYGIIVPQEFLDIPKYGCLNIHVSLLPKWRGAAPIQRAIQAGDSKTGICIMQMDAGLDTGDILNTLEVEIQDTDTSQSLHDKFAKLSIKPLLETLENIDTIKPQPQQGEPTYAHKITKQEGLIDFTKSAKEISCHIRAFTPWPSAFFMLEGEQVKVGDFEILEKSANDEVTAIIDITKNGFDIATNDKIIRFKQLQFPNKKMLNIADILNGKDLDKYIGYKIG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SYGA_SHEB9
Sequence: MTTKHDVKTFQGFILTLQEYWAQQGCAIVQPLDMEVGAGTFHPQTFLRSLGPEPMSSAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPSPDNIQELYLGSLQALGIDTQIHDIRFVEDNWESPTLGAWGLGWEIWLNGMEVTQFTYFQQVGGIECSPVTGEITYGLERLAMYIQGVDSVYDLVWTDGPLGRITYGDVFHQNEVEQSTYNFEHADVDFMFTLFDQCEKMCQHLLSLEKPLPLPAYEQVMKASHAFNLLDARHAISVTERQRYILRVRTMAKAVAESYYQAREALGFPMCK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXD07_LYCSI
Sequence: MKILFVLISILYAVYCFSSEEDVDSAYLANELEPVEDINSEQYAALEPKEEQERSCAGMGQDCKDDCDCCLNIATCNCWFGRYFCSCTFGDYQTCLRKKGKCKRNRPQSCPRSNLNRKKG
What are the official names of this protein?
U13-lycotoxin-Ls1f, Toxin-like structure LSTX-L7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 05 (agouti) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LCRG_YERPS
Sequence: MKSSHFDEYDKTLKQAELAIADSDHRAKLLQEMCADIGLTPEAVMKIFAGRSAEEIKPAERELLDEIKRQRERQPQHPYDGKRPRKPTMMRGQII
What are the official names of this protein?
Low calcium response locus protein G.
Protein: IT1B_ERYVA
Sequence: ELVDVEGEDVVNGGTYYMLPGIEGDGGGMEGAKTGRETCPITVVQSRNDVSNGEPITIESPFRSYFIPKGSLVRIGFTSPPKCAPSPWWTLALDRPQGLSVKLGEYESTEFNYSFKFEDVSSKLHSYKLSYCVREEWYEDYICKNIGIYRDSKGYRRLVVNEENPLVVVLKKVESS
What is the function of this protein?
Inhibits trypsin stoichiometrically.
What are the official names of this protein?
Trypsin inhibitor 1B, ETIB.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: P22_BORBZ
Sequence: MYKNGFFKNYLSLFLIFLVIACTSKDSSNEYVEEQEAENSSKPDDSKIDEHTIGHVFHAMGVVHSKKDRKSLGKNIKVFYFSEEDGHFQTIPSKENAKLIVYFYDNVYAGEAPISISGKEAFIFVGITPDFKKIINSNLHGAKSDLIGTFKDLNIKNSKLEITVDENNSDAKTFLESVNYIIDGVEKISPMLTN
What are the official names of this protein?
Outer surface 22 kDa lipoprotein, Antigen IPLA7.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RADP_FLOCH
Sequence: MAEFHPTAFLLPAAVTMIAGYFLCTALYNVYFHPLAKFPGPRLYAASQIPITIKRLLGDEVATFHKLHAKYGQFVRVAPGELSTINPAASRDVYGHRNPAKSIPKDFKAYYMKNQRRDGTEGLMTADDDLHRRQRKIFSPAFSDRAIREQEPLLKKYTDLLVEKAGVASDADGKVDMVMMFNFATFDFIADCVFGDSLHLLEKMEYNPFLANISAVVKFSAMRRAIRSFPYMDETFEKLIPASMKRKRMEHVKFCDDLVDRRLEKAVTNHPDFWTLVLRANEKGEGLTLGEMHQNSFLFLTAATETTSSLMSALTYLLCQNPDKMKKLVDEIRGRFKSTEEMTTVSLPPLEYLQMCIEEGLRVYPPVPGGLPRRVTADGASLDGRELPPDTVVYYAHYASYHSAAHFARPDEFHPERWASVPPSEFANDCRDAVIPFSAGPRDCIGKNLAYHEARLLLAKFLWTYDVELCEESKDWIKQKSFIVGVKRPLYVKLHRVVREK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of radicicol, a resorcylic acid lactone (RAL) that irreversibly inhibits the HSP90 molecular chaperone, an important target for cancer chemotherapy (PubMed:19101477).  The cluster encodes only two apparent post-PKS enzymes, a cytochrome P450 monooxygenase (radP) and a non-heme halogenase (radH) that introduce the epoxide and the chlorine, respectively (PubMed:19101477).  If this cluster includes all the genes required for radicicol biosynthesis, the remaining structural features of radicicol are presumably generated by the PKSs rads1 and rads2 (PubMed:19101477).  The C-2' ketone could arise if the R-PKS rads1 and NR-PKS rads2 each carry out four iterations, in contrast to the five iteration-three iteration split for the hypothemycin PKSs (PubMed:19101477).  The origin of the cis 5',6' double bond is not known (By similarity).  The radicicol R-PKS rads1 ER domain may catalyze either double bond isomerization or reduction in the third iteration (By similarity).
What are the official names of this protein?
Cytochrome P450 monooxygenase radP, Radicicol biosynthesis cluster protein radP.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ISPDF_RHIWR
Sequence: MTGKPSIAALIVAAGQGVRSGGGVPKQYRRIGGKAVLAHAVDALARHPAIGSVQVVIGAGQEDLHAEAVGGRTLPPPVTGGATRRDSVIAGLAAVDADIVLIHDAARPFLPAAVIDRLIAALDGSDGAVPALAVADTLAKGDALLGDAVPRDGLHRVQTPQAFRRADILAAHRAWDPAREATDDAQVARAHGLSVAIVEGDRSLEKLTFAADFEAAEERMAMISRTAMGFDVHGFTAGDGVQLGGVRIAHDRALAGHSDADVALHALTDALLGTIAAGDIGSHFPPSDQRWKGADSAMFLAHARDLVAAAGGIVDFVDLTIICEAPKVGPHRAAIRDRIAALLGLTAGQVSVKATTTERLGFTGRREGIAAQAVATVRVPSI
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: RNPH_CLOK1
Sequence: MRVDGRKCNQIRPVKITRNYTKYAEGSVLIENGDTKVICTASIEDKVPPFLKGRGEGWITCEYNMIPRATQVRKARDINRGRIDGRTMEIQRIIGRALRSVVDLRAIGEKTIWVDCDVIQADGGTRTASISGAFVALVDAVNKLHKQNPFTIYPIRDFVSAVSVGIVNDTRMLDLCYLEDSRAKVDMNVVMTDSGEFVEIQGTGEQNPFTREDLKELLALAEKGIKSMISAQKDSLKMDSLWIGTGGE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.