PharMolix/UniProtQA huggingface dataset:
Protein: RN_NIACI
Sequence: AQVINTFDGVADYLLTYHKLPDNYITKSEAQALGWVASKGNLADVAPGKSIGGDIFSNREGKLPAKSGRTWREADINYTSGFRNSDRILYSSDWLIYKTTDHYKTFTKIR
What is the function of this protein?
Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates.
What are the official names of this protein?
Ribonuclease, RNase Bci.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_BUCA5
Sequence: MRLNTLSPANGARHSRKRLGRGIGSGFGKTSGRGHKGQKSRSGSSIRRGFEGGQMPLYRRLPKFGFNSRKKNITTEVRLSDLSNLSTNIIDLNVLKQENIIKKNIKYAKIILSGKLTVPLIIRGLLVSKGARSEIENTGGKVEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SELA_SALTI
Sequence: MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCML_GLOVI
Sequence: MQIGRVRGTVVSSQKEPSMVGVKFLLLQLIDEAGQPLPQYEVAADGVGAGLDEWVLFSRGSAARQVAGSEKRPVDAVVIGIIDTVSVDNRPLYSKKDQYR
What is the function of this protein?
Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal molecular layer of CcmK subunits.
What are the official names of this protein?
Carboxysome shell vertex protein CcmL, Carbon dioxide concentrating mechanism protein CcmL.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family. CcmL subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=Probably forms vertices in the carboxysome.
Protein: SYM_NANEQ
Sequence: MRILVTAALPYSNGPIHLGHIAGAYLPADIFYRFVKLKGYNALYICGSDQYGSPIELNAIKLNIDPKDYASFYRKIQEEIFKKFNIKFDIYSGTAESNIHPIIVKEFFLSLFSAGLLIEKEQELPYDPKIKRFLPDRFVVGQCPYCGYEKAYGDQCEKCGRLLEPKELINPKSAITGEKVIFKKTRHLFFNIPKLKDKLKQYIESKKDVWNDFTYSWSLALLDNFKERAITRDNKWGVKVPAKEMLEILKKALKEGKTPKDFGLLIDSTNEKDLENHIKEYENKVLYVWFDAPIGYISFTFETSPEYRYYWDEKEKPYIVHFIGKDNIPFHTIFWPALIIGRNLGYKNINHILDFDIALPYQVFGNPYLNYYGKKFSKSKRWGVFLDNIDKIDIDIDYFRFYLAYIHTVSKDMSFEWDQFKEVINKELVDNIGNFIHRVLTFIYNRFNGIPPKIEHLDDKDKELLDKIKQLPEKVFNFIWKGEIGNALREIVNTSNLANKYFQEKEPWKTNDPNTIAIAFEAVKTFIILLYPFIPEKAKLLASIANIDIKWDFNQKVEKINKPFIVFHKLSDNQIEMAKQILTNPKEYDLGKKKVIGVLRYEDELYKIELECDDNPWVCLKRELDKRKIKYIYDTVKGDVPPHIIDGNTYIYLLPALEKPNLEKAEEEYGLVSYLDFAKLDMRVGKIIDVQDHPNADKLYIIKVSLGNKQKTLVGGLKQYYKKEELIGKYVVLINNLKPKQLRGITSEGMLLAADDGKEVALLMPDKPISLGSKVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_OLEA2
Sequence: MIIFPAVDIKGGQAVRLRQGKADQETVFSGDPVAMARHWEEQGGRWLHVIDLDGAFSGTPVNRELIRTICASVSIPVQLGGGIRDTVTAQAYLDAGVERLIIGTIALTDPDLFGAMCSAFPGRIGVSLDAEGGRLKTKGWVEDSGLSIYDVLPRLTEQGAAFLIYTDIDRDGMQSGVNVEALSELAVRSAIPVIAAGGVATMQDVYDLYPVSRSANLQGAITGKAIYEGSLDLAEAMRWIDSRTA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLL_THEVB
Sequence: MKLAVYGKGGIGKSTTSCNISVALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQAKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCLIVTDNGFDALFAANRIAASVREKARTHPLRLAGLIGNRTNKRDLIEKYVEAVPMPILEVLPLIEDIRVSRVKGKTLFEMAESDPSLNDVCDYYLNIADQILARPEGVVPKDVPDRDLFALLSDFYLNPQGSERSLAAV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ODP2_RICFE
Sequence: MPIKILMPVLSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIPQNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNNVSPSPKTDANLPKPHENIAKVEEQVAVIKHDASKIFASPLAKRLAKMGNIRLESVKGSGPHGRIVKQDILSYTPSTVHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNVDKLLDIREDINKSFSEDKSTRISVNDFIILAVAKALQELPNANASWGEDAIRYHNNVDISVAVAIENGLVTPIVKNANQKNIIELSREMKELIKKAKDNKLTPEEFQGGGFTISNLGMYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQVTIATIMDVTLSADHRVVDGAVGAEFLAAFKKFIESPALMLI
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: DER_BORPA
Sequence: MSFKPVVALVGRPNVGKSTLFNRLTRSRAALVADFSGLTRDRHYGEGRVGDTPFLVIDTGGFEPVAKDGILAEMARQTRQAIAEADVVVFLVDARAGVNAHDHEIARLLRKSGQQRVLLAVNKAEGMGVGNATGDFHELGLGEPHPISAAHGDGIVDLIEIALSGLVAPPADTGEQLEQDVVDHRIKLAIVGRPNVGKSTLINTLLGEERVIAFDMPGTTRDAIEIDFERDGRKYTLIDTAGLRKRGKVFEAIEKFSVIKTLQAIEASNVVLLMIDAQAEVSEQDAHIAGFVLETGRAVVVAINKWDGLDSDQRERIEREFQRKLRFLGFARMHTISALKGQGVKPLLKSVNAAHAAAFAKLSTPRLTRELQAAVEQQPPPRKGIFRPKMRYAHQGGQNPPLIVIHGNALDAVPDSYRRYLETRFRNAFDLAGTPLRIEFKSSRNPYVQEN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PA2H_POLOC
Sequence: SLFELEGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGC
What is the function of this protein?
Wasp venom phospholipase A2 homolog that lacks enzymatic activity.
What are the official names of this protein?
Basic phospholipase A2 homolog PocTX, Lys49 PLA2-like.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAX3H_CAEEL
Sequence: MTTDSITFNHILGQGRVNQLGGVFINGRPLPIHVRHAIISMAKKGIKPCHISRQLKVSHGAVSKILNRYAETGSISPGQIGGSPRARLTVQAVEKEILIACDENPQMSAAELRDWLIHKDICTKGNAPTVPAIKRLIGNKGVGVPKKMERKRLSYSIDSILGISIDECSKSSSDDEEGSSPSNDASSRRNRTSFTAEQLDVLENAFRADTYPHANARESISKETGLSEEKIMTWFSNRRARCRKNMPMYQQYNVQGFGSSPPSYPTLLPSPMMFLPSYSTSPQLNPLFFQHILQSSPPSSQSSPPSSS
What is the function of this protein?
Transcriptional activator (By similarity).  Regulates the lateral/ventral epidermal cell fate decision (PubMed:26953187).
What are the official names of this protein?
Paired box protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_ZYMMO
Sequence: MHDIRLIRSEPENFDKALSRRGFEPVSKTILEMDGERRTLALELQTLQTKRNEVSRQIGQAMKQGEKDKAEEMKAEVSAIKEKMAALEGEEAALGDKLQRFLSTIPNLAAEDVPEGKDEQDNKEVFRWGEPRQFSFKPKEHADFAPALGLDFDTAAAMSGARFALMKGAMARLNRAIGQYMLDCQTEKNGFTEIAPPLLVRDHALFGTGQLPKFEEDLFHTTDDRWLIPTAEVCLTNIVRESILDEKALPLRFTALTPCFRAEAGAAGRDTRGLIRQHQFDKVEMVAITTPEQSTAEQMRMVECAEQILQNLKLPYRRVLLCTGDMGFSATRTYDLEVWLPGQNCYREISSISDCGAFQARRMNTRYRPEEGKGNAAVHTLNGSGLAVGRTLVAILENYQEEDGTVTIPEVLHPYMNGITKLEII
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_BRUME
Sequence: MADKADKMKARLPRGFVDRVPDDLRAAEKMMATIREVYDLYGFEPVETPLVEYTDALGKFLPDQDRPNEGVFSFQDDDEQWLSLRYDLTAPLARYVAENFETLPKPYRSYRNGWVFRNEKPGPGRFRQFMQFDADTVGAPNVSADAEMCMMMADTLERLGIQRGDYAIRVNNRKVLDGVLDAIGLEGEGNAAKRLNVLRAIDKLDKFGPEGVRLLLGKGRLDESGDFTKGAQLPEAAIEKVLAFTAAGGADGAQTIANLQAVVAGNAKGEEGVQELADMQALFFAGGYEGRVKIDPSVVRGLEYYTGPVFEAELLFDVTNEDGQKVVFGSVGGGGRYDGLVSRFRGEPVPATGFSIGVSRLMTALKNLGKLDVSDTVGPVVVLVMDKDTQNLSRYQKMVSDLRKAGIRAEMYVGGSGMKAQMKYADRRAAPCVVIQGSQEREAGEVQIKDLVEGKRLSAEIEDNVTWRESRPAQITVREDGLVDAVREILDAQARDRAEQSK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_GEMAT
Sequence: MSLPVVAVVGRPNVGKSHLFNRVIGEATAIVSDEAGTTRDRHFGEAEWAGRQFWLVDTGGLVEDSHLLMDTAIRRQVMQAIEEADLMLFVVDAKVGVHPSDARIVDILRNSQKPWMLVANKVDDPASTDFYEFFRLGVTDVYPVSAQNGKGSGDLLDAVVANIPEVEEEERDAVRVAVIGRPNVGKSSFVNRLLGEDRLVVSDESGTTRDAIDAPMRYHDTDLVFVDTAGLRRQSRIDDGVEFYSALRTRRAIDSSDVCILMIDATEGLQNQDLKIATMAWEAGRGLILVINKWDLYEDKTDKSADKFKKEAVEKVPYLKFVPFLFTSAISGQRVTKVLDIVLSVQEQRTRRISTSEVNDALGDLLARLQPPQAAGREVKLNYATQVEIEPPTIAVFGNNPEAIPEHYVRFLHNGFRERWGFTGAPLRIILRRKNS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: YC023_HUMAN
Sequence: MNNSFNKEDRMSSDTMVGSCDRQTKNGAKWHGGVSSLLDFTLIYIQLSTSFQNAGHSFKKQHICSDFEVMDELSCAVYGNKFYYLLPTLTHPSIQ
What are the official names of this protein?
Putative uncharacterized protein LOC152225.
Protein: DNAJ_SHISS
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_SALHS
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CTPA1_ARATH
Sequence: MRLLLPFSSPLSATSSPSTPQFIPELPPPSQFDYSGLTKILKKSVIGTLTGALSLTLVFSSPISSVAATNDPYLSVNPPSSSFESSLNHFDSAPEDCPNEEEADTEIQDDDIEPQLVTNEGIVEEAWEIVNGAFLDTRSHSWTPETWQKQKDDILASPIKSRSKAHEVIKNMLASLGDQYTRFLSPDEFSRMSKYDITGIGINLREVSDGGGNVKLKVLGLVLDSAADIAGVKQGDEILAVNGMDVSGKSSFEVSSLLQGPSKTFVVLKVKHGKCGPVKSLKIQRQVNAQTPVSYRLEKVDNGTVSVGYIRLKEFNALARKDLVIAMKRLLDKGASYFVMDLRDNLGGLVQAGIETAKLFLDEGDTVIYTAGRDPEAQKTVVSDKKPLITAPLIVMVNNRTASASEIVASALHDNCKAVLVGERTYGKGLIQSVYELRDGSGVVVTIGKYVTPNHMDINGGGIEPDFRNLPAWDEVKERLSKCSILQQS
What is the function of this protein?
Protease involved in the C-terminal processing of the chloroplastic D1 protein of photosystem II.  This proteolytic processing is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation.
What are the official names of this protein?
Carboxyl-terminal-processing peptidase 1, chloroplastic, D1 C-terminal processing protease 1, Photosystem II D1 protein processing peptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: P53_TUPBE
Sequence: MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPDLNKLFCQLAKTCPVQLWVDSAPPPGTRVRAMAIYKQSQYVTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLHAEYSDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGKLLGRNSFEVRICACPGRDRRTEEENFRKKGESCPKLPTGSIKRALPTGSSSSPQPKKKPLDEEYFTLQIRGRERFEMLREINEALELKDAMAGKESAGSRAHSSHLKSKKGQSTSRHRKLMFKTEGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: UREF_PSEP1
Sequence: MNSDLALLRLLQLASPGLPVGGFTYSQGLEWAVEAGWVRGVDSFVGWQREQVHDTLACLDWPVLARLYRACQAEDAEAFGHWSRFLLANRETAELRLEEQQRGAALARLLDGWQLGQAPAWRASLELTQLGGMAWLAAHWAIPLRQLALGHGFAWLEGAVMAGVKLVPFGQQAAQTLLRDLGADLPAALDQALALGDDQLGGGLPLLAIASSRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOL1_CAEEL
Sequence: MCRRAEDLVLLLIPILFGYFSHASEHECKCVLFNVTSGNFHSPEFPAPLEGVPCLFYHFQAPPDHIIRLTFDVFQLPPRIGVCSSSIMLFDHSTDGLIEFGERADFEFCGKEISSGRQFFSKDQHFLLQISSGKESSRGFRGSFLAIPKKNFTSDAVEMAECSYRVEKQKAIIYSPDYPYYYPSKVNCTYHIPQRKGFQIVVNSIVMDIGRDAILQIFESVEGKFEKRLIEMVTSVQKSIYVSSTSSLLIYFSAGNNDVERAVGFVIELQYSNAVWSQSPETASECQLNINSENFKEGQLSSDKIGRFTSSSLPTKCQIVLQGYPNEKISVKFTHFNLYVPDNKNVTKRCTEVDNLSADVRVGSRLSRIDEWCGKRAPPNLMSSSNLLQLEYNTKSSKAIRESTNDDIGFRLDYKFHTDWNMGNMKAKVDKKKECRFSFNSSEHTNGKLWSANYPGLYPRNLYCEYIFHGRNDQVVHIHFEYFDIEGFNQCDETTQSDYILFSNYQTHDRTNRRFCGKTAPKGPILSESNYFRMIFSTNDIFDATGFYAHYQFITQEKSQISRVKLTISSSQTPFSSFFLVILLFTFRYIANIF
What is the function of this protein?
Accessory protein required for glutamate-gated currents.  May participate in the gating of non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptors such as glr-1.
What are the official names of this protein?
Suppressor of lurcher protein 1.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Single- pass type I membrane protein. Synapse. Note=Colocalizes with glr-1 at the cell surface. Enriched at postsynaptic membranes.
Protein: MED29_DROVI
Sequence: MNPNMNMMQMSGPPMMQVSPMMQSSPQPMMPTGPPGPVPMQQQHQQQQQQQQQQQQQQQQQAEKLDNISRVKSLLGPLRESMFLTIRSSAFTLQQNNLADNLKRDTGGHGHVPRFDKHLEDFYACCDQMELHLKTAIQCMQQLTSSQHYLPGAVTAMRMENFMQDNPAGPIPYPTYLNTVRVHVQSAKDIHDTLISAAQNISQAD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 29, Mediator complex subunit 29, Protein intersex.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLP_BRANA
Sequence: VIDVNDEW
What is the function of this protein?
May play a structural role in the elaioplast, a tapetum-specific plastidial lipid organelle.
What are the official names of this protein?
Plastidial lipid-associated protein.
Protein: GSA_STRGG
Sequence: MAYSYEAPVSQSLFDRASVVTPGGVNSPVRAFRAVGGTPRFMVSGTGPYLTDADGREYVDLVCSWGPMILGHSHPEVIAAVQEAVSRGTSFGTPGEGEVALAEEIVARIEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVVKFAGCYHGHVDALLAAAGSGVATFGLPDTPGVTGATAGDTVVLPYNDLEAVRAAFAAHPGEIACVITEASPGNMGVVPPADGFNAGLKELCAANGALYISDEVMTGFRTSKAGWYGVDGVRPDLMTFGKVMGGGFPAAAFGGRGDVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDDAAYARIDAVSAGLRSLVGEALTKEGVAHTVSAASNMFSVFFTDRPVRDYEDAKQQDVFRFTAFFHSMLAQGVYLPPSAFESWFVSTAHDERAVERVAAALPAAARAAAEATA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDM_BOVIN
Sequence: MFCWLSRLCGELSTPTRRTTQLIWSSAARSMVLSSQRIPELSSFVARTNTCGELRSSHLGQEVTLCGWIQFRRQNIFLVLRDFHGLVQVVIPQDESAASVKKILCEAPMESVVQVSGTVISRPPGQKNPKMPTGEIEIKVKTAKLLNSCKKLPFEIKDFMKKTETLRLQYRYLDLRSVQMQYNLRLRSQMVMKMREYLCNLHGFVDVETPTLFKRTPGGAKEFVIPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGVQSLIEGLLQYSWPSDKDPLVVPFPSMPFAEALASYGTDKPDTRFGMKIVDISDMFRNTEVGFLQDALSKPQGTVKAICIRKGAKYLKRKDIESIRKFAADHFNEEVLPIFLKTNENWNSPVAKFIMEEQGLGLVKLLETQEEDVVLLTAGEHKKACSLMGKLRLECADLLEARGVVLRDPALFSFLWVVDFPLFLPKEENPQELESAHHPFTAPHPSDIHLLYTEPHKVRSQHYDLVLNGNEIGGGSIRIHNSELQHCVLDTVLKEDVKLLSHLLQALDYGAPPHGGIALGLDRLMCLVTGAPSIRDVIAFPKSFRGHDLMSNAPDSIPPEELKPYHIQVSWPMDAETEKSSSNHPCRSES
What are the official names of this protein?
Aspartate--tRNA ligase, mitochondrial, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NU4LM_CANLA
Sequence: MSMVYINIFLAFILSLMGMLVYRSHLMSSLLCLEGMMLSLFVMMSVTILNNHLTLASMMPIVLLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KINB_PSEAI
Sequence: MSMPLPMKLRTRLFLSISALITVSLFGLLLGLFSVMQLGRAQEQRMSHHYATIEVSQQLRQLLGDQLVILLRETPDGQALERSQNDFRRVLEQGRANTVDSAEQAALDGVRDAYLQLQAHTPALLEAPMVDNDGFSEAFNGLRLRLQDLQQLALAGISDAETSARHRAYLVAGLLGLVGVAILLIGFVTAHSIARRFGAPIETLARAADRIGEGDFDVTLPMTNVAEVGQLTRRFGLMAEALRQYRKTSVEEVLSGERRLQAVLDSIDDGLVIFDNQGRIEHANPVAIRQLFVSNDPHGKRIDEILSDVDVQEAVEKALLGEVQDEAMPDLVVDVAGESRLLAWSLYPVTHPGGHSVGAVLVVRDVTEQRAFERVRSEFVLRASHELRTPVTGMQMAFSLLRERLDFPAESREADLIQTVDEEMSRLVLLINDLLNFSRYQTGMQKLELASCDLVDLLTQAQQRFIPKGEARRVSLQLELGDELPRLQLDRLQIERVIDNLLENALRHSSEGGQIHLQARRQGDRVLIAVEDNGEGIPFSQQGRIFEPFVQVGRKKGGAGLGLELCKEIIQLHGGRIAVRSQPGQGARFYMLLPV
What is the function of this protein?
Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes.  KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals.
What are the official names of this protein?
Alginate biosynthesis sensor protein KinB.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.