PharMolix/UniProtQA huggingface dataset:
Protein: SYP_ECO27
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_GAHVR
Sequence: MSEPQSWSVMASQMTSAQLIRVYLDGSMGIGKTSMLNEIPTHSLMGVPVLKVFEPMKYWRYYFTDLVTTVNDTCDRRRRGEFSLFQSSMIVTALQSKFADPYLVFHERLSSKCHRITGTRGNPSLILILDRHPISATVCFPIARHLTGDCSLEMLISMIIRLPQEPPGCNLVIVDLHDEKEHVSRLSSRNRTGEKTDLLMLRALNAVYSCLVDTIMYANHICPYSKDEWESEWLDLPWFDTSLATTFINEPRTDYRGSRVSLHHTLLAIFKRRELCAEDGSLSTTHAWILWGLLMKLRNINVERFNITGLSTTKCVESFMDTMSERLVTHSSWNDAFEIEADVLAYNKEMAM
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: SEP2A_XENLA
Sequence: MSKQQAQFTNPETPGYVGFANLPNQVHRKSVRKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVVPGAADKIERTVDIEASTVEIEERGVKLRLTVVDTPGYGDAMNCVDCFKPIISYVDNQFERYLHDESGLNRRHIVDNRVHCCFYFISPFGHGLKPLDVEFMKALHNKVNIVPVIAKADTLTLRERERLKRRVLDEIEEHGIKIYQLPDAESDEDEDFKEQTRLLKASIPFTVVGSNQLIEAKGKKVRGRLYPWGVVEVENTEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKKGVTSSKVEHVEVTKDQILQEKEAELRRMQEMITRMQAQMQIQGQSGDAQHL
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Required for normal organization of the actin cytoskeleton.  Plays a role in the biogenesis of polarized columnar-shaped epithelium.  Required for the progression through mitosis through regulation of chromosome congression.  During anaphase, may be required for chromosome segregation and spindle elongation (By similarity).  Probably plays a role in ciliogenesis and collective cell movements including convergent extension during gastrulation.  In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Controls cell shape and not polarization of cells during convergent extension.
What are the official names of this protein?
Septin-2A, Septin-A, XlSeptA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cell projection, cilium membrane. Note=Localizes at the base of the cilia near the morphological distinction between the cilia and plasma membranes (By similarity). Cytoplasm, cell cortex.
Protein: YRJ5_CAEEL
Sequence: MQIGEYELTFIDVAVFVVFLVALNKIVKRMLVAKINEPAKYEIEQLEERDMTMEEIESMRREENRCLVIVEDKIYDLSGSQDLYDNNRDLFESSEGCGPEWAPICARKYPFVGHVLKN
What are the official names of this protein?
Uncharacterized protein K10D2.5.
Protein: WPRA_BACSU
Sequence: MKRRKFSSVVAAVLIFALIFSLFSPGTKAAAAGAIDQAAALENGKEQTGAMKEPEQVKWYKVTPGATDIQKNSHMALTVKSDSVLNVSVYPSKEKALKDETFEMYRSFTAEDGKSEVIFPYAWSGPYYVKVEYLGEEEPEDGGTAEAAAEAKYTIGYKGTKKQPSDLEEEEACPVEMSVDQKKSGKGILDKLRSIRDEQLSQTAEGKELTSLYYKAAPFIVAKLALNKTARNEIYQDLVTLKPLFDDVSENGASSSYKVTEKDQKAINRLYDKALQSVPSFLKEEIKKQADRLNMKQLQGKTAGAILTENNIAAKSEVQTTKVIFKVKDNKSLSSVHNEMKGFSASAQSKKDISNVKKAKKLFDNLYSFELPKDEKQNGAYTASAKRVKSAAATLSKMSNVEFAEPVQEYKSLANDIQYPYQWPLKNNGENGGVKNADVKYEPANTLLSKRKLNDTLIAVVDTGVDSTLADLKGKVRTDLGHNFVGRNNNAMDDQGHGTHVAGIIAAQSDNGYSMTGLNAKAKIIPVKVLDSAGSGDTEQIALGIKYAADKGAKVINLSLGGGYSRVLEFALKYAADKNVLIAAASGNDGENALSYPASSKYVMSVGATNRMDMTADFSNYGKGLDISAPGSDIPSLVPNGNVTYMSGTSMATPYAAAAAGLLFAQNPKLKRTEVEDMLKKTADDISFESVDGGEEELYDDYGDPIEIPKTPGVDWHSGYGRLNVMKAVSAADLQLKVNKLESTQTAVRGSAKEGTLIEVMNGKKKLGSAKAGKDNAFKVNIATQKQDQVLYLKATKGDAKTSYKVVVVKGKPSGTPKVNAVKTKDTAVKGKANSKAMIRVKNKSKKVIASAKADAKGTFSVKIKKQKAGTVLYVTAVDTDKKESKEAKVVVEK
What is the function of this protein?
CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges.
What are the official names of this protein?
Cell wall-associated protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Released into the medium.
Protein: IHFB_ECOL5
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RHBG_PIG
Sequence: MAGSSRRAGGRRLQLPLLCLLLQGATAILFAVFVRYNHETDAALWHWGNHSNPDNEFYFRYPSFQDVHTMIFVGFGFLMAFLQRYGFSSVGFTFLLAAFALQWSTLVQGFLHTFHGGHIHIGVESMINADFCAGAVLISFGAILGKTGPAQLLLMALLEVVLFGLNEFVLLSLLGVKDAGGSMTIHTFGAYFGLVLSRVLYRPQLEKSKHRQSSVYHSDLFAMIGTIFLWIFWPSFNSAPTPLGDGQHRTALNTYYSLTASTLSTFALSALVGRDGRLDMVHVQNAALAGGVVVGTSAEMMLTPFGALAAGFLAGTVSTLGFKFFTPILESKFKIQDTCGVHNLHGMPGVLGALLGVLVAGLATHDSYGEGLESVFPLIAEGQRSSTSQALHQLFGLFVTLIFASVGGGLGGLLLRLPFLDSPPDSQCYEDQIYWEVPEEHADLAQGSLRPEEPDTQA
What is the function of this protein?
Ammonium transporter involved in the maintenance of acid-base homeostasis.  Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism.  May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (By similarity).  May act as a CO2 channel providing for renal acid secretion (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type B, Rhesus blood group family type B glycoprotein, Rh family type B glycoprotein, Rh type B glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: L_BDVV
Sequence: MSFHASLLREEETPRPVAGINRTDQSLKNPLLGTEVSFCLKSSSLPHHVRALGQIKARNLASCDYYLLFRQVVLPPEVYPIGVLIRAAEAILTVIVSAWKLDHMTKTLYSSVRYALTNPRVRAQLELHIAYQRIVGQVSYSREADIGPKRLGNMSLQFIQSLVIATIDTTSCLMTYNHFLAAADTAKSRCHLLIASVVQGALWEQGSFLDHIINMIDIIDSINLPHDDYFTIIKSIFPYSQGLVMGRHNVSVSSDFASVFAIPELCPQLDSLLKKLLQLDPVLLLMVSSVQKSWYFPEIRMVDGSREQLHKMRVELETPQALLSYGHTLLSIFRAEFIKGYVSKNAKWPPVHLLPGCDKSIKNARELGRWSPAFDRRWQLFEKVVILRIADLDMDPDFNDIVSDKAIISSRRDWVFEYNAAAFWKKYGERLERPPARSGPSRLVNALIDGRLDNIPALLEPFYRGAVEFEDRLTVLVPKEKELKVKGRFFSKQTLAIRIYQVVAEAALKNEVMPYLKTHSMTMSSTALTHLLNRLSHTITKGDSFVINLDYSSWCNGFRPELQAPICRQLDQMFNCGYFFRTGCTLPCFTTFIIQDRFNPPYSLSGEPVEDGVTCAVGTKTMGEGMRQKLWTILTSCWEIIALREINVTFNILGQGDNQTIIIHKSASQNNQLLAERALGALYKHARLAGHNLKVEECWVSDCLYEYGKKLFFRGVPVPGCLKQLSRVTDSTGELFPNLYSKLACLTSSCLSAAMADTSPWVALATGVCLYLIELYVELPPAIIQDESLLTTLCLVGPSIGGLPTPATLPSVFFRGMSDPLPFQLALLQTLIKTTGVTCSLVNRVVKLRIAPYPDWLSLVTDPTSLNIAQVYRPERQIRRWIEEAIATSSHSSRIATFFQQPLTEMAQLLARDLSTMMPLRPRDMSALFALSNVAYGLSIIDLFQKSSTVVSASQAVHIEDVALESVRYKESIIQGLLDTTEGYNMQPYLEGCTYLAAKQLRRLTWGRDLVGVTMPFVAEQFHPHSSVGAKAELYLDAIIYCPQETLRSHHLTTRGDQPLYLGSNTAVKVQRGEITGLAKSRAANLVKDTLVLHQWYKVRKVTDPHLNTLMARFLLEKGYTSDARPSIQGGTLTHRLPSRGDSRQGLTGYVNILSTWLRFSSDYLHSFSKSSDDYTIHFQHVFTYGCLYADSVIRSGGVISTPYLLSASCKTCFEKIDSEEFVLACEPQYRGAEWLISKPVTVPEQITDAEVEFDPCVSASYCLGILIGKSFLVDIRASGHDIMEQRTWANLERFSVSDMQKLPWSIVIRSLWRFLIGARLLQFEKAGLIRMLYAATGPTFSFLMKVFQDSALLMDCAPLDRLSPRINFHSRGDLVAKLVLLPFINPGIVEIEVSGINSKYHAVSEANMDLYIAAAKSVGVKPTQFVEETNDFTARGHHHGCYSLSWSKSRNQSQVLKMVVRKLKLCVLYIYPTVDPAVALDLCHLPALTIILVLGGDPAYYERLLEMDLCGAVSSRVDIPHSLAARTHRGFAVGPDAGPGVIRLDRLESVCYAHPCLEELEFNAYLDSELVDISDMCCLPLATPCKALFRPIYRSLQSFRLALMDNYSFVMDLIMIRGLDIRPHLEEFDELLVVGQHILGQPVLVEVVYYVGVVRKRPVLARHPWSADLKRITVGGRAPCPSAARLRDEDCQGSLLVGLPAGLTQLLIID
What is the function of this protein?
Displays RNA-directed RNA polymerase activity.  The mRNA guanylyl transferase and mRNA (guanine-N(7)-)-methyltransferase activities are supposedly provided by cellular enzymes (PubMed:22138959).  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  Functions either as transcriptase or as replicase.  The transcriptase synthesizes subsequently three subgenomic RNAs, assuring their capping and polyadenylation by a stuttering mechanism.  In replicase mode, the polymerase replicates the whole viral genome without recognizing the transcriptional signals.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GL35_ORYSJ
Sequence: MEYGFKAAGLVFVVLLLQQAPVLIRATDADPLQDFCVADLNSEVTVNGHACKPASAAGDEFLFSSKIATGGDVNANPNGSNVTELDVAEWPGVNTLGVSMNRVDFAPGGTNPPHVHPRATEVGIVLRGELLVGIIGTLDTGNRYYSKVVRAGETFVIPRGLMHFQFNVGKTEATMVVSFNSQNPGIVFVPLTLFGSNPPIPTPVLVKALRVDAGVVELLKSKFTGGY
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 3-5.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RS11_PSEP1
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQIAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNSCGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AZOR1_LISMO
Sequence: MTNVLFIKANGLPAERSVSVALYEIFLTEYKKSHPDDNVTELDLFEADLPYYDVTMMSGLHKEAAGETLSPEEKRLADIANSYLDQFLAADKIVMAFPLWNFSIPAQFLTYLFYLNQAGKTFKYTANGPVGLVADKKIALLNARGGIYSDGPMQSFEMSLNYVKNVLAHFGISEPEMVIVEGHNAKPDQAKDIISAGAKEAVELAKIF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PHOU_METJA
Sequence: MPKKFEEILKEVENDLIEMAELCAEQTENAVKAFIESDRELAKQVRKRDTTIDLMEMKIEEKCIKAIALYQPVSGDLRELMTAIKISSKLEKVGDNASKICKILLKSDVEGNRKNELLIVMKDYLINMLKNAMIAFKTRDESLARDVYNMDKRLDDLYEQLYRSMISKIIENPKNLTLYTEIIFAGKYLERSGNIVASIGDRIVYMITGERIKEEEIEEELKKEKDIEKNIDQIND
What is the function of this protein?
Plays a role in the regulation of phosphate uptake.
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU homolog, Pst system accessory protein PhoU homolog.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERA2_ARATH
Sequence: MAFSSSCSSVKAVNSRWTSPSPSPSSRFAVLPAFLHRRYATSVKLTAISAALKTVEQTTLTEDNRFSTVGSDSDEYNPTLPKPRILVTEKLGEAGVNLLREFGDVDCSYDLSPEDLKKKVAESDALIVRSGTKVTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNAPMVAPEVLSELTPYIVLAEKLGRLAVQLASGGKGVQSIRVVYRSARDRDDLDTRLLRAMITKGIIEPISDSYVNLVNADFIAKQKGLRISEERMVVDSSPEYPVDSIQVQILNVESNFAGAVSDAGDISIEGKVKYGVPHLTCVGSFGVDVSLEGNLILCRQVDQPGMIGQVGNILGEQNVNVNFMSVGRTVLRKQAIMAIGVDEEPDNKTLERIGGVSAIEEFVFLKL
What is the function of this protein?
Involved in the plastidial phosphorylated pathway of serine biosynthesis (PPSB).
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase 2, chloroplastic, PGDH.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SH3K1_MOUSE
Sequence: MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSRPEGFLPASLLPFPAHGAKGKTTFEGTILYRAAPGKTEGHRRYYSLRETTGSESDGGDSSSTKSEGANGTMATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPPATSTPDPSKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGNRPKKPPPPSAPVVKQGAGTTERKHEIKKIPPERPETLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKTNSLNRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSALSGILDKDLSDRSNDIDLEGFDSVISSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPDIFDSPSPEEDKEEHISLAHRGIDVSKKTSKTVTISQVSDNKTSLPPKPGTMAAASSGPASLSSVASSPMSSSLGTAGQRASSPSLFSTEGKPKMEPAVSSQAAIEELKMQVRELRTIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK
What is the function of this protein?
Adapter protein involved in regulating diverse signal transduction pathways.  Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins.  The association with CBL, and thus the receptor internalization, may be inhibited by an interaction with PDCD6IP and/or SPRY2.  Involved in regulation of ligand-dependent endocytosis of the IgE receptor.  Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit (By similarity).  May be involved in regulation of cell adhesion; promotes the interaction between TTK2B and PDCD6IP.  May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4.  Is involved in modulation of tumor necrosis factor mediated apoptosis.  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape and migration (By similarity).  Has an essential role in the stimulation of B cell activation (By similarity).
What are the official names of this protein?
SH3 domain-containing kinase-binding protein 1, Regulator of ubiquitous kinase, Ruk, SH3-containing, expressed in tumorigenic astrocytes.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein. Synapse, synaptosome. Cell junction, focal adhesion. Note=Localized in endocytic vesicles containing clustered receptors. Colocalizes with ASAP1 in vesicular structures. Colocalized with actin microfilaments and focal adhesions (By similarity). Colocalized with MAGI2 in synaptosomes (By similarity). Translocation to EGFR containing vesicles upon EGF stimulation is inhibited in the presence of SH3KBP1 (PubMed:21830225). Colocalizes with ZFP36 in the cytoplasm (By similarity).
Protein: SYE_METAR
Sequence: METKDIEILIQKFALQNAYKHGSVPQAGAVTGKLLGTHPELRPHAKELMPIVQKVLADIGQMSQDEIKAKLSEIAPELIEELSVKKEVRRGLPPLDTSMLKPGQKVTLRIAPNPNGPPSLGNARGIIVNHEYARMYDGVFIMRFDDTDPSIKKPMIEAYTWYVEHAKWLGCPPDKVVAASDRLPLYYEQAEKLIDLGKAYVCTCDNEVFHDLKEAGKPCPHRETPPAENMEKWKKMLAGGYGGKEAVLRIKTDIAHKDPAMRDWVAFRIVTEPHPKTGTKYMVWPMLDFESAMEDHFLGVTHIIRGKDLMKTADKQKYIYRYLGWEYPHVSHWGRVRLLGFGKFSTSVMKKGIEAGEYRGWDDPQLPTVVALKRRGIEPEAIRNVMINMGVTETDIEFSMDTLYAENRKIVDPKANRYFFVPDPVVLKVNGAPFTTAKAPLHPQDHKRGFREMCVAENPEILIPKSDADNARPGDILRLKDLYNVRITGSDPLTGDYIGNDLSVLKQGAKIVQWVTREGGVPTRVIGPDGEFHGIAECDIRNELNNVVQFERFAFVRIDTINGVVLAYYTHP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_CUCSA
Sequence: MAIHLYKTSTPSTRNGAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNAGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPT_PROMA
Sequence: MKTPIAIGAEKKSLITPLPASIDPLRLPEHIAIIMDGNGRWANAKKLPRAMGHSAGVDALKQTLRLCNDWGIGVLTVYAFSTENWSRPKEEVNFLMTLFERVLKKELEALNLEEVQISFLGDLDQLPTRLQDLINEATELTSGNNGIRFNVCTNYGGRRELVLAAQKLAQRVLQGDLDPSFIDEHTFAGELLTSSYADPDLLIRTSGEMRISNFLLWQLAYAEIHVTDTLWPDFDSISLTKALIDYQSRRRRFGGVDPTVNDYDQV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: NANA_ECOBW
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_SULIM
Sequence: MSAEKISISLPKELYRELEDFITRKGIPDRSKIFQIALRNYLDENREGTEIIYGIINLVYDHEEASEALTEIQHEYKDNIISTLHLHVNERLCIEAIAVKGEKSKLVELNNRLGQIRGILKARLLISFPYEKT
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: 5DNU_YERPE
Sequence: MSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAFVAHALAIIKNRKFNGNLNAERIALLAMYHDASEVITGDLPTPIKYHNPKIAHEYKKIEKVAQQKLIEMLPKELQHDFRCLLDEHYYSEEEKALVKQADALCAYLKCLEELSAGNNEFIQAKARLEKTLAIRQSPEMDYFMAVFVPSFSLSLDEISLDSLD
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YPO2559, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_AQUAE
Sequence: MPTFNQLVKYGREKRKKKSKAPALQGCPQKRGVCVRVYTVTPKKPNSALRKVARVRLSNGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGALDAAGVEGRRQSRSKYGTKRPKEEKGG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CYSD_SHEPW
Sequence: MAAKELSHLQQLEAESIQIIREVAAEFDNPVMMYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTDWKFKEMIAFRDAQAKEFGFELLVHKNPDGIEMGVGPFTHGSAKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKHHTWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQESIELVPLYFAQKRPVVERDGMMIMVDDDRLPLEEGETVKDELVRFRTLGCYPLTGAMYSEADTLEKIIEEMLLTRSSERQGRLIDSDQSASMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: YXXD_BACSU
Sequence: MSYNFIKSNKENDFYPVNQSEIEEVEKNLNLKLPSELVNFYLEVGYGFIKGSEFNTNRILDPYSVRDFRLRINDFEFYPDIEIYDEFENDKLIFFEGSESALMSIELNDNNKNPIYYYDIQIATSLTEFLRKIEENDQYYLDLLDDE
What is the function of this protein?
Immunity component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  In situ neutralizes the toxic effect of cognate toxin YxiD (PubMed:34280190).  Neutralizes the toxic activity of cognate toxin YxiD upon expression in E. coli.  Does not have immunity protein activity on other LXG toxins (PubMed:22200572).
What are the official names of this protein?
Immunity protein YxxD, ORF1.
What are the subcellular locations of this protein?
Cytoplasm.