PharMolix/UniProtQA huggingface dataset:
Protein: RSXB_ECOSM
Sequence: MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: LEUC_BORBR
Sequence: MAQTLYDKLWDAHVVHQESDGTCLLYIDRHLLHEVTSPQAFEGLALAGRQPWRVGANLAVADHNVPTLNRAQGIEDPISRLQVDTLDDNCAKYGITEFRMNDLRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHVLATQTLLMKKAKSMQINVEGELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVEGRMTVCNMAIEAGARSGMVAVDDKTIDYFRGRPFAPVGVLWDQAVGYWRTLHSDAGARFDRVINVDARDIKPQVTWGTSPEMVLPVDGRVPDPDREKDDVRRSGMERALEYMGLKPNTPLVDIRVDRVFIGSCTNSRIEDLRAAAVVARGKRVAANVRQAMVVPGSGLVKQQAEREGLDKIFIEAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAVAGHFVDVRSFR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MDTG_ECODH
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_BURO1
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIIVNGKPIADYFSRETSLMIVRQPLELTNHGQTFDIKVNVNGGGETGQAGAVRHGITRALIDYDATLKPSLSSAGFVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: FRO6_ARATH
Sequence: MDDYETPLLSKDSSSSSSVITSSLKWILKVVMSMIFVTWVVFLMMMYPEQLGDDFLTFVSSKTFLGTTGTMFLIFSCPILVISVLASLYLIISGEDKVFTKKKISKFPRFRLWTFPVLVDGPFGVVSAAEFLGIMVFSVFFLWSIYAYTLRNLDLLERFHVLPKNRSILLLEVTGLRLGMIGLLCMVFLFLPISRGSILLRLIDIPFEHATRYHVWLGHITMAFFSLHGLCYVVGWIIQGQLLELIFSWNAIGIAILPGVISLVAGLLMWVTSLHTVRKNYFELFFYTHQLYIVFIVFLALHVGDYMFSIVAGGIFLFILDRFLRFCQSRRTVDVISAKSLPCGTLELVLSKPPNMRYNALSFIFLQVRELSWLQWHPFSVSSSPLDGNHHVAVLIKVLGGWTAKLRDQLSNLYEAENQDQLISPQSYPKITTCVEGPYGHESPYHLAYENLVLVAGGIGITPFFAILSDILHRKRDGKACLPSKVLVVWAIKNSDELSLLSAIDIPSICPFFSKKLNLEIHIYITRQSEPRLEDGMVHKVVHPSVKLPRTNGCSMSVLVGTGDNIWSGLYLIISTIGFISMITLLDIFYIKRYNITTWWYKGLLFVGCMVASVLIFGGLVVVFWHRWEHKTGEVEANGNDKVDLNGEETHNPSAAELKGLAIEEDVQNYTTIRYGTRPAFREIFESLNGKWGSVDVGVIVCGPATLQTTVAKEIRSHSIWRSANHPLFHFNSHSFDL
What is the function of this protein?
Ferric chelate reductase involved in iron uptake by shoot and leaf cells.  May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates.
What are the official names of this protein?
Ferric reduction oxidase 6, AtFRO6, Ferric-chelate reductase 6.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCA1B_NEUCR
Sequence: MSGYPGAGYNGGGYVPPPQPQYGGYYPPQPAYNAYQQPPPQQQQYMVYHQPSPGPQQHQHWNPQQQTPAPQGYGNPPNSHYGRPEANMPTVNSNSYAHGNHQAPPPPPQAPQQFGYGAPADYAFRYSQCNGRHKALLIGINYFGQRGQLRGCINDVRNMSSYLVEHFRYKREDMVILTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGYDEVIYPVDFRQVGHITDDEMHRIMVRPLQAGVRLTAIFDSCHSGTALDLPYIYSTQGILKEPNLAKEAGQGLLGAISSYSQGDLYGVANNIMGIFKKATGGNDAHARTLATKTSPADVVMFSGSKDDQTSADATIASQATGAMSWAFINALKKNPQQSYVQLLNSIRDELQMRYTQKPQLSCSHPLDTNLLFVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: TRPB_PSEU2
Sequence: MTQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYVGRPNPLYFAERLTEFCGGAKIYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLLGAEIVPVTSGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVGGGSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDGQITDAHSISAGLDYPGIGPEHAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETAHALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAAAEHTQEQLV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GLGB_SERP5
Sequence: MPVLPDRDVIDQLFSGNSADPFSLLGMHAADNGLQVRALLPDASEVWLLEQQTGRRLVQLNCDDARGFFSATVPRRKTPFRYQFEVRWQDHQQIVDDPYRFGTLLQDIDSWLLAEGTHLRPYERLGAHLSTLDDVEGVSFAVWAPNAQRVSVVGEFNFWDGRRHPMRLRRENGIWELFLPGVKAGQLYKYEIIDCYGNTQLKADPYAFEAQMRPDTASLVTPLPEVVENTPQRQRANDFDRPISIYEVHLGSWRRHTDDNFWLSYGELAVQLIDYVKDMGFTHIELLPINEHPFDGSWGYQPLGLYAPTRRFGTPADFKDFVAAAHRAGINVILDWVPGHFPSDAYGLANFDGTALYEYADPREGFHQDWNTLIYNYGRHEVRNYLAGNALYWLERYGIDALRVDAVASMIYRDYSRAEGEWVPNYYGGNENLEAIAFLRYTNQSVGKERPGAVTLAEESTDYPGVTLPPESNGLGFHYKWNLGWMHDTLNYMQCDPVHRKYHHNQMTFGMLYAYTENFVLPISHDEVVHGKKSILDRMPGDAWQKFANLRAYYGFMWAHPGKKLLFMGCEFAQGREWNFDSSLDWHLLEGLDGWHHGVQRLVRDLNHCYQQQAPLYERDYRPDGFEWLVVDDHDNSVFAFARYDAHGNELIAVSNFTPVPRHHYRIGISRPGEYREILNTDSHHYHGSNTGNQGRVVSEQIGNHGREHSISVTVPPLATIYLLREAQ
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: OAF3_YEAST
Sequence: MGYDSQVRTKKRHRITVVCTNCKKRKSKCDRTKPCGTCVRLGDVDSCVYLTDSSGQPESSPSLNDADPLRKQSTPAERISPGFIKKRRSSQTRQDEDHWQRVRELENQSSLYYLPIHEETPFFIDLIPNGFYLETKRSADNLFGLFTDRAIENRDPYLQAMVTFRSIAIKKMMDKLGSNGNNVKNGSLPKSFEALSTFDADDERHISDDVVGKGNNFRMHQTIHKSLFNKFAQYRENNAKKFSSETILAKDYLPPLKILESEVLALFEEKIYNMIPIFDMKVLRHEITIFYQNIVEKGNPISIKHYDHMVFCIILLIIKICRLSVQFSKLTPYIYPVLQEIDTSKFLALVKHYLFETKVLRKCNLLQLQCLILLRFLHWCAPEDGDGPETQYCQILMGTIISSCKEMGINWYCFSHPEKYSFKINRHTRPSYDIMKPSDYISVFRKIWSYVLFWDRKMCFISGEECQIGKTLQCHFKEEADTPTWYIRMLTLDNLMKKINDTLNDDPGKVDLNLLHRLINDLKRNFHILKSLSKNEKETMRHFDFEMEWIIDLFSLSLLHGEMIFYEYDCNITKFYKSFQDLWDMVIHISEKCYNYFFNSDALEVDSLTKFYTNRIVEIVANKVLVIVPAFILRGDRFKTIQYADKKKMIEFLYGVSSVYFNEFGFEYYRCFRKMFTAKIAYKILNRSCEKDAWRIILKFLLNELKLEDNGDSYIDYNDMRLNDICPIILEFQETVQKYDGYRPDILSIWNNEFYPIGKYNDDMTGFKFQMRIKEMQEFLDMEKYSDRFNIFSSFYDHASSQLAKHTEVDTNISITNEQVAEIPQKELLQQPLAPALPVNDLIVSEFDVIEDIFDPVDFVSFF
What is the function of this protein?
Transcriptional inhibitor with a significantly increased number of target genes in response to oleate.
What are the official names of this protein?
Oleate activated transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the OAF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: HPPA_HELCL
Sequence: AGGIAEMAELGPEVRKKTDKLDAVGNTTAAVAKGFAIGSAALTALALFTAFAEEVVKSPGVSSALHGSHFVLNLLEPKIIIGLFIGGTVPFLFCAFAMEAVGKAAFEMIGEVRRQFREIPGLMEGKAKPDYARCVDISTRAAIRQMIAPGLLAVITPLIVGFGFGAQALGGMLAGVTVAGVLLAIFMANAGGAWDHA
What is the function of this protein?
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.
What are the official names of this protein?
Putative K(+)-stimulated pyrophosphate-energized sodium pump, Membrane-bound sodium-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, Na(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHOSP_RYSV
Sequence: MSGSGSEQTPRLTRSSSRSTLTGVASGRVEKIRSSPKSLDRIAKKYKDFDPETAKIIRADLEETQADKTMEVGGSTQESAQQITGAKRPNEEDQGGAQEAAKRVNRSNKVNSLLTSNGVTDPAKSKISNYIVGRLNANNIEADSVMVAECTNIAIHAWKEGKKYLDDKIISQATTTIPTLITNLVSNANTLSNVIASLNNVPDKLVSDIRTQVENVSNQTGQKAAKRDVLLKSSESIYNNAVKESKVDFINNYLTSSGVNVDELRKDSHHYRTVVSRIEKKYTVLVMMPEHEEHHTLKEKVATNRTFVKESAQTLSQKYVTQ
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RHLB_HAMD5
Sequence: MNKTHLTDQKFSDFALHPLVIKAIENQGFYHCTPIQALSFPITLAGRDVAAQAQTGTGKTLAFLASVFNYLLTNAADETRQCEQPRALIMVPTRELAIQIYTDAETLSQFTSLKMGLAYGGDGYDKQLKILESGVDILIGTPGRIIDYAKQNFIHLNALQVIVLDEADRMYDLGFIKDIRWLFRRMPPAEKRLNMLFSATLSYRVRELSFEQMNHPEYIEVEPLQKIGSQIQEELFYPSNEDKMRLLQTLIEEEWPDRCIIFANTKQRCEDIWGHLVADGHRVGLLTGDVAQRKRIQILDDFSKGYLDILVATDVAARGLHIPKVTHVFNYDLPENVEDYIHRIGRTGRAGEKGYSISLACEAFASHLSTIEACTGHRIPTSEYNKEALLTDLPQPKRLQRHHRHYAGSRNQGASRKPRSPQ
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBG1_DROME
Sequence: MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASGYSQGEKLQEEVFDIIDREADGSDSLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLVQEYEAATREDYMQFSVKRGNGPVDSKSEDSRSVTSAGS
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-1 chain, Gamma-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: ARLY_LIGS1
Sequence: MAIKKMWGGRFQEGSSKLVDEFGASISFDKHMAYEDLEGSLAHVKMLKHTNILSADDADKIIAGLHILQDKLANGELTFSTELEDIHMNIESLLTQEIGDVAGKLHTARSRNDQVATDLHLYLKNRLEIVIDEIKNLQKVIVKKAEENVETVMPGYTHLQHAQPISYGHYLMAYYQMFQRDIERFEFNKKHTNISPLGAAALAGTTFPIDREFTAKELDFDNIYANSLDAVSDRDFVLEFLSNASILMMHLSRFCEEIILWCSYEFGYIELSDKYSTGSSIMPQKKNPDMAELIRGKSGRVYGHLTALLATMKSLPLAYNKDLQEDKEGVFDAVKTVIPSLKIFAGMLDTLTVNKDKMLHATEHDFSNATELADYLATKGIPFRKAHAIVGQLVFEGIENNTTLSDIPLEKYKEINSEIGEDIYQFLQSKVAVQRRHSLGGTGFDQVKLQIKNAKKQLNL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIGD5_BOVIN
Sequence: MYSAGPPAVPAPRRCRRPPPGRPMQPPRPPAPAPVPAARPPPPAPGPRPRVAVKMAFRKAYSIKDKLQAIERVKGGERQASVCRDFGVPGGTLRGWLKDEPKLRWFLEQLGGEVGTQRKKMRLANEEEIDRAVYSWFLALRQHGVPLSGPLIQAQAEAFARQIYGPECTFKASHGWFWRWQKRHGISSQRIYGEAEPVAAGPAPGPPVKQEPAQPTRAGPLPDRAASTPAPAEGGYGDEQIYNANVTGLYWKLLPEQAAPVGAGGCGRRWRGDRVTVLLAANLTGSHKLKPLVIGQLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVRRYLRRSCLQQKAVLLVAHPPCPSSEARMPALEESEETRRRCRPEPTGPPEELQTPDGAVRVLFLCRGSGRAHIPAPLEQGVVAAFKQLYKRELLRLAVSCAGGSPLDFMRSFMLKDMLYLAGLSWDLVQAGSIERCWLLGLRAAFEPRPVEERAGQPAGQAEEAAEHSRVLSDLTHLAALAYKRLAPEEVAEWLHLDDDGGLPDGGREDWGPSRPPVLVPGGPLLPASLPSAVAGGAEEEEEEAIPTAGEAVRGLETALRWLETQDPREVGPLKLVQLRSLISTARRLGGIGPSPMVPDDGL
What are the official names of this protein?
Tigger transposable element-derived protein 5.
What is the protein family that this protein belongs to?
Belongs to the tigger transposable element derived protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXT_THEKO
Sequence: MVKVGVIGLQGDVEEHIWAARRALENLGVSGDVIWLKKPEQLENISAIIIPGGESTTISRLMVKNGLFEPVKKLGEEGLPIMGTCAGLIMLSKEVIGATPEQKFLELLDVKVNRNAYGRQVDSFEAPIKLAFSGEPFPGVFIRAPRIVELLSERVKPIAWLGDRVVGVEQDNIIGLEFHPELTDDTRVHEYFLRKAV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: COA5_DANRE
Sequence: MPKYYEDKEDDGRACSGLREDFKACLLQHDCVVKEGKKPSECLKEGHCRSMQVAFFECKRSMLDTRSRFRGRKGE
What is the function of this protein?
Involved in an early step of the mitochondrial complex IV assembly process.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 5.
What is the protein family that this protein belongs to?
Belongs to the PET191 family.
Protein: KEFG_ECOL5
Sequence: MSQPAKVLLLYAHPESQDSVANWVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGC
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MDEP_STAAR
Sequence: MNYLKHKFYNLLTTIIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIVFAVEHLMDYFRKMLPENAYFRGATFHLISYMVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
What is the function of this protein?
Involved in multidrug efflux.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEN4B_MOUSE
Sequence: MAEERPPRLVDYFVVAGLAGNGAPIPEEKWVPEPTGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQTSAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSARTLPRRPYKLLLATLTSLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRLEREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPPVLEGSESTPQYCYDGFPELKAELFESPQEQQGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSATVPELWARCLLGHCYGLWFLCLPAYVRSVPSRVRALHTAYHVLREMENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLKDRRQQQQQQQQQQQQKQQVAEQQKSGSSQTEPYLERPSPTRPLQRQTTWAGRSLREPSSPMGRLVKSGSLGSARGTQPTVEAGVAHMIEALGVLEPRGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGSKTSGCQEEVGTPRKGLGARLQQLLTPSRRASASRIPPPELPSDLPPAARRSPMDSLLWPRERPGSTASESSASLGSEWDISESSLSSLSLRRSSERLSDTPGAFQPPSLEILMSSCSLCHACDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLVENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGPPPSQLSQGPSPWLTPDPASVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRQRRAQMPTPKAIDCRKCFGAPLEC
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB10.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).
What are the official names of this protein?
DENN domain-containing protein 4B, Brain-specific gene 4 protein, Brain specific protein 4.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RL2_ECOLC
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: G3P_MELGA
Sequence: AEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDKSLKIVSNALCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPFGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFHVPTPNVSVVDLTCRLEKPAKYDDIKRVVKAAADGPLKGILGYTEDQVVSCDFNGDSHSSTFDAGAGIALNDHFVKLVSWYDNEFGYSNRVV
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus.
Protein: AT5G1_BOVIN
Sequence: MQTTGALLISPALIRSCTRGLIRPVSASFLSRPEIQSVQPSYSSGPLQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 1, ATP synthase proteolipid P1, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RS12_DESAP
Sequence: MPTISQLIRRGRETVAQKSASPALRECPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGYEVTTYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTAGVQNRNRGRSKYGAKRPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: OBI1_HUMAN
Sequence: MAQTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACRVPITPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQRFGSSLFKMSSEMHSLHNHLQSPWSTSFVPEKRNKNVNQSTKRKIQSSLSSASPSKATKS
What is the function of this protein?
E3 ubiquitin ligase essential for DNA replication origin activation during S phase (PubMed:31160578).  Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase (PubMed:31160578).
What are the official names of this protein?
ORC ubiquitin ligase 1, OBI1, RING finger protein 219.
What are the subcellular locations of this protein?
Chromosome. Note=Association to chromatin is cell cycle-regulated, absent from mitotic chromosomes, is associated with chromatin from G1 and partially released from chromatin from mid S-phase.
Protein: FB37_ARATH
Sequence: MGQSTSAAGNSILNRRRSKSFTLKFPIESIESEISQPDYTSSLPDECLALVFQFLNSGNRKRCALVCRRWMIVEGQNRYRLSLHARSDLITSIPSLFSRFDSVTKLSLKCDRRSVSIGDEALVKISLRCRNLKRLKLRACRELTDVGMAAFAENCKDLKIFSCGSCDFGAKGVKAVLDHCSNLEELSIKRLRGFTDIAPEMIGPGVAASSLKSICLKELYNGQCFGPVIVGAKNLKSLKLFRCSGDWDLLLQEMSGKDHGVVEIHLERMQVSDVALSAISYCSSLESLHLVKTPECTNFGLAAIAEKCKRLRKLHIDGWKANLIGDEGLVAVAKFCSQLQELVLIGVNPTTLSLGMLAAKCLNLERLALCGCDTFGDPELSCIAAKCPALRKLCIKNCPISDVGIENLANGCPGLTKVKIKKCKGVLGGCADWLRTVRPMLSVNADTMEQEHEEAASNDVVGGSQENGIEFPQLNSQIMASSIASSSRNRSGYFKSGIGLFSGMSLVPCTSRQRRASR
What are the official names of this protein?
F-box protein At1g47056.