PharMolix/UniProtQA huggingface dataset:
Protein: SYP_VIBC3
Sequence: MRTSNYLLSTLKETPNDAEVVSHKLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAIETLMPVVQPFELWEETGRSEKMGPELLRFTDRHERPFVLSPTAEEVITALVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKAGLEKSYEAMHVAYCKAFDRMGLDYRPVLADTGAIGGNGSHEFHVLAESGEDLIAFSTESDYAANIEKAEAVAPAIERPAPTQAMTLVDTPNAKTIAELVEQHGLPIEKTVKTLFVKASDEIDAPIVALIIRGDHELNEIKAEKLAEVASPLEMASEEEIRALIGAGPGSLGPVGLKLPFIVDRTVAVMNDFGAGANIDGKHYFGINWGRDVELGKVEDLRNVVEGDPSPCGKGTLMLKRGIEVGHIFQLGTNYSEKMNCGVLDSNGKNVILEMGCYGIGVSRVVAAAIEQNHDDYGIIWPDAIAPFQVAIVPMNMHKSERVQQAAEKLYAELTAAGIEVLFDDRKERPGVMFSDMELIGVPHTIIIGDRSMDEGHFEYKNRRQGEKEAVAMESIIDFIQAKLA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS23_EUPES
Sequence: MGKTHGMGAARKLKSHRRTQRWADKSYKKSHLGNEWKKPFAGSSHAKGIVLEKIGIEAKQPNSAIRKCARVQLIKNGKKIAAFVPNDGCLNYIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVSGVSLLALFKEKKEKPRS
What are the official names of this protein?
40S ribosomal protein S23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MCA1A_NEUCR
Sequence: MSYGYPGQGYGPGGGHHQPPPPQWDGQQQHHHQGGYGYSNPGQGQYNPQPPQDQGYGGYHQQPPQQYQQGSYNQGQYPPQGGYGGPYGQQQQHHQQGHSQRPPGPPPDGYDIYGYPIGSGHQTRNQGSHEIHEIPSGTQQFGHGAPEGYGFQYSNCSGRRKALLIGINYLGQDAELHGCINDTKNVSAFLVENYGYKREDMVILTDDATNPLLQPTKENILRAMQWLVAGAQPNDALFLHYSGHGGQTKDTDGDEDDGYDEVIYPVDFKTAGHIVDDQIHDTVVKPLQPGVRLTAIFDSCHSGSVLDLPYIYSTKGVIKEPNLAKEAGQGLLAAVGSYARGDIGGMASSLFSVAKTAFGGGNEAYERTKRTKTSPADVIMWSGSKDDQTSADATIASQATGAMSWAFITAIKANPKQSYVQLLNSIRDVLETKYTQKPQLSSSHPIDVDMLFVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: Y3521_METJA
Sequence: MWRGVGMVVQQFINRIRNCPLARDIIKKFFIPVIKERKNIEKEVEDILKVLRKNYCSGEYANKDCICAWFKFFEDVGRLHEALELKAFWEIIFPNHLNDLSESLQLFISNYAYMRPFGSSYSSIRVRIHGFIGAVCIDRNFNLHNNTWISNICNCYENNLRMLGLGFYTSDTLDPRYNINPSCNINSTTTNKCGLLYIISNTQITASLVSYLLNLLRNGNIYDAYNFLIRIRGVGDKIACLFLRDISIIHNLMLYGDCRDLLYKPIDRVVKKVIEELVKCKCKLNYNFDINEVLEKFDYTECRCIQKLRKNAKIDSNDFKTLYPYKIFLYEYSKKCKLDQRYVEMGMWFFNSKVAKYYNRRLCKYTIQEACKDLIKRLRKAINNTNIRYIGNNQFEININGKIIIVSEDELIDLILKGEIEIYDELLDIIFF
What are the official names of this protein?
Uncharacterized protein MJECL21.
Protein: RS19_MARSD
Sequence: MPRSLKKGPFIDDHLLKKVVKAQESGDRKVIQTWSRRSTIIPEMVGLTFAVHNGRKFIPVFVTENMVGHKLGEFSPTRTYYGHAADKKSKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MURL_SALTO
Sequence: MPNEQLRRMDAFTFPSYSFDLSTGEALFDYALTGPDGEQRFTEVITLPLPASPPSDERVATLGRVLELLHVIAGVSYYKTAAPHRLVLPAPLGPSAVALVTAVYTKGLAEYAYRNALPHVLRLRPEVPSGEVTPPVGYDTDGRRPLSAVGGGKDSIVSLEALRRDGLDPLPFSVNPNRVIEAVNVASGLPALAARRRIDPVLFDLNAAGALNGHIPVTAINSLIAVATSVLNGLGPVVMSNERSASDPNLIWDGHQINHQWSKGVEAEGLLRGALEEHAGLTDPYFSLLRQLSELHIARTFARIGGYDDVVTSCNAAFKLRGASDRWCRDCPKCRFVFLALAPFMPRERITRVFGGDLLADPAQLPGYRELLGVDGHKPFECVGEVEESVVALSLLGEQSGWRDAPVVSALIDAVPETAWKTAATSAVFTPGGPSFTPTRYADALGSLTEPARNLPG
What is the function of this protein?
Cell wall formation.  Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.
What are the official names of this protein?
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase, UDP-MurNAc-L-Ala-L-Glu epimerase.
What is the protein family that this protein belongs to?
Belongs to the MurL family.
Protein: ALDH3_YEAST
Sequence: MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK
What is the function of this protein?
Cytoplasmic aldehyde dehydrogenase involved in ethanol oxidation.  Involved in pantothenic acid production through the conversion of 3-aminopropanal to beta-alanine, an intermediate in pantothenic acid (vitamin B5) and coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Aldehyde dehydrogenase [NAD(P)+] 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_ECOLI
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows highest phosphatase activity in the presence of Ni(2+) and hydrolyzes pyrophosphate, canonical 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi.  Displays a metal-independent phosphodiesterase activity toward 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP.  Without metal or in the presence of Mg(2+), this protein hydrolyzes 2',3'-cyclic substrates with the formation of 2'-nucleotides, whereas in the presence of Ni(2+), it also produces some 3'-nucleotides.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PEBP1_PONAB
Sequence: MPVDLSKWSGPLSLQEVDERPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWEGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK
What is the function of this protein?
HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system.  HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.  Seems to be mediated by a specific receptor (By similarity).
What are the official names of this protein?
Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2061_LACPL
Sequence: MTVSTGIWILIVVIGVLVGLTGGFFGARHYMQNYLKQNPPISEEMLRSMMMQMGQRPSEKKLHQMLNSMKAASKNDNK
What are the official names of this protein?
UPF0154 protein lp_2061.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TIG_SYNFM
Sequence: MNVSVVDLSENQKKLQVEIPPEKVRQEIEGKYREMSRRIKIKGFRPGKVPRSIIKSYYGKTIEQEVSSQFIQETFPEALKETDLKPLVEADVSETHFNDSGSFSYTAIVDVCPPFELEGYRGLEIRKPSIDVADEQVDSELQRLREQHAELRTLETERPAREGDVAVIDFTPSVDGKVFEKGKSADYMAEIGKKAVHPDFDANLIGRRAGETVSFEVDYPENAPMREIAGKRVLFEVTVKEVKEKVLPELDDDFAQAVNSRFDALDALKQTIREELLKREEYQARSDVQQQILDQLLSKVKIELSAKVIDREVDRMVGNLLHQFESQGLKMDVSKFNTPEIRADYRPQAERNILRRLILEKIADQENLKLTDEEIEQVYQEVARYARMDVATVKHEFADSAVVEQSKESKIQEKVFRFLESEAVSGHISQEEKSE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RBL_ARGFE
Sequence: GVGFKAGVKDYRLTYYTPEYKTKDTDILAAFRMTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMLTSIVGDVFGFKALRALXXEDLRIPPAYSKTFLGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQKDHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVFPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BR2B_SYLGU
Sequence: MFTMKKSLLLLFFLGTVSLSLCEQERGADEDDGGEMTEELKRGVITDALKGAAKTVAAELLRKAHCKLTNSC
What is the function of this protein?
Antimicrobial peptide.  Active against the Gram-positive bacteria S. aureus FDA209P (MIC=16. 5 ug/ml) and B. subtilis ATCC 6633 (MIC>64 ug/ml), and the Gram-negative bacteria E. coli O111 (MIC=8. 2 ug/ml) and E. coli ATCC 25922 (MIC=8. 2 ug/ml).  Not active against the fungus C. albicans.
What are the official names of this protein?
Brevinin-2GHb, AMP-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: MURI_ALIF1
Sequence: MPKHILIFDSGIGGLSVYKEIKYQLPLAKYIYAFDNAAFPYGELTESVLIERTTHIISKLCSKFPIDIVVIACNTASTVVLPSLREKLDIPVVGVVPAIKPAALVSNKIGLLATPATVKRSYTYDLIKSFAPISDVQLLGSTRLVEMAEEKMIGIDVDITELKEILSPWQNKVDTIVLGCTHFPFLKNEIKKALGNKILLIDSGEAIARRVKQLLNGDEVESAVLFEGEVFCSAPSIKEEALNHTFKELNFSSLQCLGYPKF
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NUOK_METI4
Sequence: MHIGLTHYVVASGILFAIGLAGIILRRDLIVILMCLEIMLNAANLALVAFSRFNANLLGQVLVFFVITVAAAEVAVGLALIVALYRVKHTTKAEDITMLKF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PX11A_BOVIN
Sequence: MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADNEKVVMKLKKLESSVSTGRKWFRLGNVVHALQATQQSVRATDLVPRICLTLASLNRVIYFICDTVLFVRSTGLASGVNKEKWRRWAARYYYYSLLLSLVRDLYEVSLQMKQVAHDRAKREKSPSQDTLGYSVADEETEWLQSLLLLLFHSLKRHPPLFLDTVKNFCDILNPLDQLGIYKSNPGIIGLGGLVSSVAGIITVAYPQMKLKTQ
What is the function of this protein?
May be involved in peroxisomal proliferation and may regulate peroxisomes division.  May mediate binding of coatomer proteins to the peroxisomal membrane.  Promotes membrane protrusion and elongation on the peroxisomal surface.
What are the official names of this protein?
Peroxisomal membrane protein 11A, Peroxin-11A, Peroxisomal biogenesis factor 11A.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: OXDC_ARTBC
Sequence: MKFGSALVAAVAAVAGVAAKDYGGVPGQPIQKSGKGAVFSGATNPQLDLQNPSNINGQPATDIGLVPNLKWSFSLSKTRMFHGGWIREQVISDLPASHDIAGAQVHLTKGGIRQMHWHRVAEWGYVYAGSILVFAVTEDGQYQIDKLTPGDIYYFPKGAAHSFQGIEDENEVLVAFDEGDFDKIGYLFPPYYSNINLQLSNAFNYRTTFQVAEWIAHTPQDVLAKNFNISTGGTFDKTKSNMLEIINSTTSTHNVTGPNGALMGNSSYTFHIRDAPEIQVPGGGGTIQIVDSKNFPISKTIACAIVRLKPGALRELHWHPTAEEWLYFHSGNARATVYVSGGLSRTFDFTAGDTGVFPDNAGHYIENVSEDEDLVYLELYKADRVADVSLSQWLALTPHDIAAAAINVPIDVIDKLKKDKQYIIQ
What is the function of this protein?
Converts oxalate to formate and CO(2) in an O(2)-dependent reaction.  Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2), and oxalate-dependent, H(2)O(2)-independent dye oxidations.
What are the official names of this protein?
Oxalate decarboxylase ARB_02208.
What are the subcellular locations of this protein?
Secreted.
Protein: SYME_ECOL6
Sequence: MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESELMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
What is the function of this protein?
Involved in the degradation and recycling of damaged RNA.  It is itself a target for degradation by the ATP-dependent protease Lon.
What are the official names of this protein?
Endoribonuclease SymE.
What is the protein family that this protein belongs to?
Belongs to the SymE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJU2_HUMAN
Sequence: MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGASSLSQLGAYLDSDDSNGSN
What is the function of this protein?
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961).  Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity).  May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453).
What are the official names of this protein?
Splicing factor YJU2, Coiled-coil domain-containing protein 94.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family. YJU2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: REV_HV1M2
Sequence: MAGRSGDRDEELLKAVRYIKILYQSNPYPKLEGTRKARRNRRRRWRARQRQIHQISERILSTCLGRLQEPVRLQLPLLEKLHINCSEDCGQGTEKGVGSPQISVESRAVLGSGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: MMAA4_MYCTU
Sequence: MTRMAEKPISPTKTRTRFEDIQAHYDVSDDFFALFQDPTRTYSCAYFEPPELTLEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRRAVERFDVNVIGLTLSKNQHARCEQVLASIDTNRSRQVLLQGWEDFAEPVDRIVSIEAFEHFGHENYDDFFKRCFNIMPADGRMTVQSSVSYHPYEMAARGKKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGFTVPEPLSLRPHYIKTLRIWGDTLQSNKDKAIEVTSEEVYNRYMKYLRGCEHYFTDEMLDCSLVTYLKPGAAA
What is the function of this protein?
Involved in the biosynthesis of hydroxymycolate, a common precursor of oxygenated mycolic acids (methoxy-mycolate and keto-mycolate).  Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation of the hydroxylated product at the distal position.  Involved in the activation of the antitubercular drug thiacetazone (TAC).
What are the official names of this protein?
Hydroxymycolate synthase MmaA4, Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
Protein: ASNA_ECODH
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_STRPJ
Sequence: MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KEX1_SCHPO
Sequence: MISKLLKIVLLTAGVIGNTLADSRIHEQYLVKAFPNEPVDYEGRMHAGHLNQTDQLDGDLFFWMFESVKPEYEHRSILWLNGGPGCSSEDGSLMEVGPFRLDDNNTFQLNPGRWDELGNLLFVDQPLGTGYSYSLAKDFQSNNEKMANDFSIFFEKFLEEFPERANDEWFIAGESFAGQYIPHIAAKLKEKNLVNLGGLAIGNGWINPLSHYETYLNYLVEKGMVDFESELGQYLHHSWAECLLAFDKIGSGSGDLSKCESFLGDILYMVSKEPGKACMNMYDISLESTYPTCGMDWPYDLSYLTEFLSTREAMTSLNVNLEKVHDWEECNDDVALQYAREGIESSSKLIQDLVSTVPILLFYGENDFLCNYLSGEKLTRSLEWNGAVGFQNQSAQPFYLPGYSDQPSGSYVSSRNLTFARIVEASHMVPYDHPNEMKTLITAFFNNDFASLPSVPKPSPDLGNGNYKWLYLGLIPVALTIIILFSIYLCRRFGLFGLSKQRYQPISPTP
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase kex1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Vacuole membrane; Single-pass type I membrane protein.
Protein: DNCH_SYNE7
Sequence: MADYQFQRVIRFGDTDAAGVVYFAQLLSICHEAYEAAIAALGIELRSFFSDRGSVILPIVHAEIDYQRPTYCGDRLEIELQATALGRDRFRVDYRLSHNHQPVATAQTIHLCLESQTRQRSPLPERLQDWLQITAD
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: RR11_ADICA
Sequence: MSNKSRKIRSRGGKRGVQKGVIHIQASFNNTIITVTDVRGQVIIWSSAGACGFKGTRKSTPFAAQAAAENAIKASVDRGMKQAEVMMSGPGPGRDTALRAIRRSGIILSFIRDVTPMPYNGCRPPRKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADK_YERPS
Sequence: MNNRRFDCIGIVGHPRHPAALATHEILYHWLKARGYAVMVEQQIAHDLNLTDAITGSLADIGQKADLAVVVGGDGNMLGAARVLARYDIKVIGVNRGNLGFLTDLDPDNALQQLSDVLEGEYLSEQRFLLETHVRRTNQQSRISTAINEVVLHPGKVAHMIEFEVYIDDRFAFSQRSDGLIIATPTGSTAYSLSAGGPILTPTLDAIVLVPMFPHTLTARPLVISSTSTIRLKFSHITSDLEISCDSQIALPIQEGEEVLIRRSDFHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.