PharMolix/UniProtQA huggingface dataset:
Protein: FUCI_STRZP
Sequence: MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRYARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSGSCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSLFGTEDLESADYRACQLLGPLHK
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZYG1_CAEBR
Sequence: MSGGKSGTKLSSFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAASQTRIKEEIKTMKLLRHRNIVQFYETFFENGETYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLIAAVKYIHDENILHRDLSAGNVFIKDATKSTITVKLGDFGLATNLGQHGTACTIVGTPGFIAPQVFGQNYDQAADVYSLGAVLYTMLTKHTPPTKGPPNLESLKKRNPSAADLVERMMHTDARRRIQLKEIVMTDYVKAKMGEATPGSREHSRDSRSQRSREPFRSSRDGISLERRPPARSSSQPVNSRRDPDGYRAAHEMPTTSRTSVEPDRARVRHRLSARGIGSSQEDDLRQQIWPIRMERLVGQRVRTPGGRYIVEMNTRCRFEVVSKGNIVLRILVVEYDPHLLIQTVYVHKMSNRVEHARNETDDLIELTRSPISYTSLSQLPKEVMNDYMRLEKMMVSTIASRVAKITHRRPSQFPDASAQLMENGDLRIRFPNSLIVRRKSNGEVHNYIDGFANNKEEVRGLQLSKVREVYACLTQLEQCLSRMNPTMKILPMVFSAGPDIVATYNNSPSSILPSTSSQASRFPFSEISSSQQLVPHSAPIPNKPLSSRTTSSLNVRNGVSSDENTAPAATRQKYKARLDPVTGRIVSVQAEDNRKLRCSTSKPDQFIFTDPSISSSEQRFMRNGRVPERASEMLHALLVYMKKKQN
What is the function of this protein?
Protein kinase that plays a central role in centrosome duplication.  Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization.  Maternal copy regulates centrosome duplication during later cell cycles.  Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome (By similarity).
What are the official names of this protein?
Probable serine/threonine-protein kinase zyg-1, Zygote defective protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the centrosome. Present at centrioles only immediately before their duplication (By similarity).
Protein: REX_STRPF
Sequence: MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIHAQKVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_CHRVO
Sequence: MSPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPTELDLGRLLPLLSRRGIRAVALRHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAAVESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSAGAEVIADGNIHVYAPLRGRALAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SKIL_PONAB
Sequence: MENLQTNFSLVQGSTKKLNGMEDDGSPPAKKMVTDIHANGKTINKVPTVKKEHLDDYGEAPVETDGEHIKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTVFLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSEQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKNSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE
What is the function of this protein?
May have regulatory role in cell division or differentiation in response to extracellular signals.
What are the official names of this protein?
Ski-like protein, Ski-related protein.
What is the protein family that this protein belongs to?
Belongs to the SKI family.
Protein: Y326_THEMA
Sequence: MDVIQRIKEKYDEFTNAEKKIADTILSDPKGIIESSISDLSEKAGVKSEASVVKFYKKLGLNSFQQFKVLLAQSISRAPLEIVYEDVSSEDDTKTITEKIFKATVRAILDTLNWLDIDSIERTVDLFKNAQRIIFIGFAASAAVAFDAFHKFTRIGKNCLFSNDEHIIAAILATASPSDLLVAISHTGETISVVNFAKKAKEMKMPVVTITGNRKSTLAKYSDVVLATNTKETKIRTDAMTSRIVQLVILDTIYTLLAARDPRAIENLNKSRLAVSELKY
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator TM_0326.
Protein: OM14_YEAST
Sequence: MSATAKHDSNASPNSDSEDGHHHNNKKECAIEYLKARLNSASAVACGYLQAFVSKTQDFAKVCFLELQNPVVLVNLLLHSSVVCYLCNGYANHNARFLKGKPNSTVLATTAGALGLLTLDGIISKKYYSRYDKK
What are the official names of this protein?
Mitochondrial outer membrane protein OM14, Outer membrane protein of 14 kDa.
Protein: CERI2_PLAF7
Sequence: MLGTKFILNIFKNKFNNLSTRFIKYVIKSYKRTCPHISDFEPFSSMYYYTGLHNYRTFYLLIKINEIFNINKYKQIYIIVNTDKYDFTTDDIETNKKNRIYLDQRVDIKIRQCDEVIRINLFTTKLTKKVHIGEIKIDINASIISKCFPKNEWFVCIKDGQEVCKVQLSFYKTQKYACPSECMFIHDGLEIWKDKSKSGSTKKIDINNIHKNFDDNDEHLAMIDIDTDINDISLIQKLKLISFVLEQEICVFDFYAYVLKYMYAKEIMGEWFLCFLCFKNNKDQEEINIETIIERNIHRDINIPMLNIQRIVVDKRNNTNANIIYTYQDEKYTLSIHSKKNLYYIIDAITIFTNDLKILKESFGDELEYRKNIIMKENTMKKLMGKRRLSSPRFRKNLPKSTHKMIKEMYDEQDCSHDVKESNTQFFENDMKTNEIKNDNIQTDEIKNDNIQTDEIKNDHIQTDEIKNDNIQTDEIKNDNIQTDEIKNDHIQTDEIKNDNIQTDEIKNDNIQTDEIKNDHIQTDEINNDHIQTDEIKNDHIQTDEIKNDHIQTDEIKNDINTSNEIFFKAQLENTIQNI
What is the function of this protein?
Plays an important role in rhoptry physiology and thus is essential for merozoite invasion of host erythrocytes.
What are the official names of this protein?
Rhoptry surface protein CERLI2, Ag-1 blood stage membrane protein homolog, Pfmag-1, Cytosolically exposed rhoptry leaflet interacting protein 2, PfCERLI2.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, rhoptry membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes below the host erythrocyte cell membrane (PubMed:19777263). Localizes to the cell membrane of merozoites (PubMed:19777263). In merozoites, localizes to the cytosolic face of the rhoptry bulb membrane (PubMed:35140336).
Protein: GRPE_FRATO
Sequence: MSKQEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKILVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLAH_ECO24
Sequence: MNALTAVHNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSGAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: RDGC_SHIDS
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CYMEE_MELDN
Sequence: GIPCGESCVYIPCITAAIGCSCKSKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mden-E.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RS4_BRUSI
Sequence: MSKRESAKYKIDRRLGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDFGVQLRAKQKLKGFYGDISEKQFRKTYEEAARRKGDTGENLIGLLESRLDAVVYRAKFVPTIFAARQFINHGHVNVNGRRVNIQSYRLKVGDVVEVREKSKQLAIVLEAVQLAERDVPDYIDVDHNKMVATYNRVPGLSDVPYAVQMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNLI_METS5
Sequence: MKFKLIAEYFDRLEKISSRIQLTSLLSDLFKNTEREVIDKVVYLIQGRLWPDFTGMPEIGMGEKFLIKAIAMAYGNKEEEVEKLYKNIGDLGEVAYSLRSKVKGVSILSFVGGNQEAGELDVMEVYNELVKIATSTGEGSRDIKIRIFAGLIKKATPIEAKYLVRFVEGRLRLGIGDATVLDALAITFGGSADYRPIVERAYNLRADLGDIARVIATEGIEKLKNISPTPGIPIRPMLAERLPDPEEIMEKMNGKALVDYKYDGERAQIHRKGDKVTIFSRRMENITDQYIDVTEYVKQFVKGDNFIVEGEIVPVDPESGEMRPFQELMHRRRKNNIAEAIKEYPVNLFLFDLMFFEGEDYTTKPLPERRAKLEEILASNDKVHIASHIIADRVDKLREYFYQAISEGAEGVMVKSIGPDSIYQAGSRGWLWIKLKRDYQSEMADTVDLVVVGAFYGKGKRGGKFSSLLMAAYNPEKDVFETVCKVASGFSDQELDEMQKKINELKREQKHPRVVSDMIPDVWVSPTLVAEVIGAEITISPLHTCCRGEKGGLSIRFPRFIRWRDDKSPEDATTNQEIMEMYSKQLKKIEEKPVDENI
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: RL6_CLOB6
Sequence: MSRVGKLPVAIPNGVTVTVTPDNVVTVKGPKGELVKAMSNKINIAVEDNSVVVTRDNDHKDVRALHGLTRALINNMVTGVNEGYIKTLELIGVGYRAQLQGKKLVLSLGFSHPVEMEAVSGVEFEVEGGTKVKVKGIDKELVGAVAADIRKWRKPEPYKGKGIKYENEVIRRKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DISA_MYCBP
Sequence: MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDENVEAICDGGFSLDVRYAATRLRELCKMDGAVVLSTDGSRIVRANVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGERHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVMTVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVRDYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDSALSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGAMWARHVRDGLSQLAESTISDQ
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: AROK_PROMT
Sequence: MAVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSISSIFEKDGEKVFRDVEKKVLKEISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRRSIKRLESDHKRRPLLLGDNLAENFSQIYESRKPIYLESDLRIEVEDQSPYEVATMVAEHLQSILIDQEPQAERHTTEL
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNRC2_HUMAN
Sequence: MGGGERYNIPAPQSRNVSKNQQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQNGGKNKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFNPSDKEIMTFQLKTLLKVQV
What is the function of this protein?
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429).  May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429).  Required for UPF1/RENT1 localization to the P-body (PubMed:19150429).  Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514).  Also acts as a nuclear receptor coactivator (PubMed:11574675).  May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity).
What are the official names of this protein?
Proline-rich nuclear receptor coactivator 2.
What is the protein family that this protein belongs to?
Belongs to the PNRC family. PNRC2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body.
Protein: SOSSC_NEMVE
Sequence: MAFQQHGNQEVRNRKILQGLEEKKRQMMNQQQGGGAGPLPGPSHVARPPTDAGNTSASRIHEPIVRYPNQTHQLAISQRQALEHAHSVSPGFYITQDSMYGNLILPVIPRVESE
What are the official names of this protein?
SOSS complex subunit C homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
Protein: BIP_DEBHA
Sequence: MLKVNSRFWISGFTLAYVLLAVILPLLTPNQGQALAAEGETDNDTESYGTVIGIDLGTTYSCVGVMKNGKVEILANDQGNRITPSYVAFTPEERLIGDAAKNQASSNVENTVFDIKRLIGLKYNDKMVQKEIKHLPYKIDKKDGKPVVKVEFNDETKTFSPEEISGMILTKMKSIAEEYMGKKITHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKTEGEKQIIVYDLGGGTFDVSLLSIEGGVFEVLATAGDTHLGGEDFDFKVVRYLSSVFKKKHNIDISGNSKAISKLKRETEKAKRTLSSQMSTRIEIDSFVDGIDFSETLSRAKFEELNIESFKKTLKPVQQVLKDAGFKKSDVDDIVLVGGSTRIPKVQELLEKFFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVHDIVLLDVNPLTLGIETTGGVMTTLINRNTAIPTKKSQIFSTAADNQPTVLIQVFEGERALAKDNNKLGKFELTSIPPAPRGVPQIEVTFSLDANGILKVEAMDKGTGKSESITITNDKGRLSKEDIDRMVEEAEKYAEQDSELKAKIESRNSLENYAHMLKGQVKDESENGLGSKLNDDDKETLDDAIKETLEFIEDNYDSATSEEFEEQKQKLIDVASPITSKLYGGGAGGADEAQFGDDDSDDEFVHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.  Is required for secretory polypeptide translocation.  May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, Immunoglobulin heavy chain-binding protein homolog, BiP.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CYB_EUMPE
Sequence: MTNIRKSHPLIKIVNEAFIDLPAPSNISSWWNFGSLLGVCLTMQIMTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHIGRGLYYGSYTYTETWNVGIILLFAVMATAFMGYVLPWGQMSSWGATVITNLLSAIPYIGTDLVGWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYV_CERS4
Sequence: MPMDKTFNAAEAEARLYDAWEKAGAFRAGANASRPETFCIMIPPPNVTGSLHMGHAFNNTLQDILTRWHRMRGFDTLWQPGQDHAGIATQMVVERELAKSGQPGRREMGREAFLEKVWEWKEQSGGTIVNQLKRLGASCDWSRNAFTMDPNFQRAVLKVFVDLYEKGFIYRGKRLVNWDPHFETAISDLEVEQVEVNGNMWRLRYQLADGATYRHPVAFDEEGRPTEWEERDYLTVATTRPETMLGDTGIAVNPADERYAHLIGKEVVLPLVGRRIPIVADDYADPSKGTGAVKITPAHDFNDWGVGQRTGLRAINVMSGRATMFLIENPDFTEGCAPSEEALALDGLDRYEARKRVVALAEEQGWLDGIDQDRHMVPHGDRSKVAIEPMLTDQWFVDTAQIVQPAIDAVRTGRTEILPERDAKTYFHWLENIEPWCISRQLWWGHQIPVWYGLDIWPARFEDDGDDTLDEVEIFELLEDGAFNHADPTHHCAFDFEGVSEKFLDDLASLPHPLNNARVVEVASRAEAIDRLAQALADYNLNEDPTHLVYPVWRDPDVLDTWFSSGLWPIGTLGWPEETPELARYFPTNVLITGFDIIFFWVARMMMMQLAVVNEVPFKTVYVHALVRDEKGKKMSKSLGNVLDPLELIDEFGADAVRFTLTAMAAMGRDLKLSTARIQGYRNFGTKLWNACRFAEMNGVWEGHATQAAPPAATATVNRWIIGETGRVREEVDAALAAYRFDSAANALYAFVWGKVCDWYVEFSKPLFDTEAAAETRATMGWVLDQCMVLLHPIMPFITEDLWATTGSRTKMLVHSDWPSFGAELVDPAADREMSWVISLIEEIRSARAQVHVPAGLKLPVVQLALDAAGREALARNEALILRLARLEGFTEAASAPKGALTIAVEGGSFAIPLEGVIDIGAEKARLAKTLEKLEKDMAGLRGRLGNPNFVASAPEEVVDEARTRLEQGEEEGAKLSAALARLSEIA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_SHIFL
Sequence: MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFPASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGGIA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_ACIC5
Sequence: MQPTHSVNCEPLKSLVRTVPDFPKPGILFYDITTLLKDRQGFAKLIDALAEHYIGKNIDLVLGIEARGFIFGPALAYRLNAGFVPVRKPRKLPARTVRVTYDLEYGSDTLEIHEDAIEPGQRIVLVDDLLATGGTMEATVKLVRQLGGEIAGLAFAVELDFLKGRERFPDLDVFSLLHYSE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A1D_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-D.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RIBB_CLOBH
Sequence: MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIRECSGIVCLCLTDKKVKKLGLTQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILTAVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDLMRLAGYNPAGILCELTNPDGTMARLPQIINFAKKHNLAVLSIEDIIKYKKITT
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.