PharMolix/UniProtQA huggingface dataset:
Protein: DSBA_ECO27
Sequence: MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKELTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA.  Acts by transferring its disulfide bond to other proteins and is reduced in the process.  DsbA is reoxidized by DsbB.  It is required for pilus biogenesis (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ANDB_EMEVA
Sequence: MQPITQIPLTFDTVVNLLGSASGIGWILNYILMTYYSFRDKTYSMSMLPLCCNIAWEFVYGILCPSSTFVVRPVILSWLVLNCLVVYAAIKYSPNEWAHAPLVQRHLPLLFTVGIAACTGFHIALIRKFDPATAFLWSARSCQVLLSIGGLFQLLCRSSTKGGSYVLWLSRFLGSICGVLKMTLMWKYGESRFPWLDDPLTAYCIALWIISDVLYGVVFYSLRSKELAGAGKAKAI
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of anditomin, a fungal meroterpenoid (PubMed:25216349).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase andM (PubMed:25216349).  DMOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHDMP) by the cytochrome P450 monooxygenase andK, which is further prenylated by the prenyltransferase andD to yield farnesyl-DHDMP (PubMed:25216349).  Further epoxidation by the FAD-dependent monooxygenase andE leads to epoxyfarnesyl-DHDMP (PubMed:25216349).  The next step involves the terpene cyclase andB that converts epoxyfarnesyl-DHDMP into preandiloid A through opening of the epoxide ring followed by the cyclization of the farnesyl moiety (PubMed:25216349).  Preandiloid A is in turn oxidized at the C-3 hydroxyl group to yield preandiloid B by the dehydrogenase andC (PubMed:25216349).  The dioxygenase andA is solely responsible for the dehydrogenation of preandiloid B leading to the enone preandiloid C, as well as for the intriguing structural rearrangement to generate the bicyclo[2. 2. 2]octane core, transforming preandiloid C into andiconin (PubMed:25216349).  FAD-binding monooxygenase andJ then produces andilesin D which is reduced by dehydrogenase andI to yield andilesin A (PubMed:25216349).  Action of acetyltransferase andG followed by a spontaneous acetate elimination leads then to andilesin B, which is in turn substrate of the short chain dehydrogenase andH to yield andilesin C (PubMed:25216349).  Finally, the dioxygenase andF catalyzes the transformation of andilesin C to anditomin (PubMed:25216349).
What are the official names of this protein?
Terpene cyclase andB, Anditomin synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GUF1_TRYB2
Sequence: MRLWNRFSRLGNLLCACAACGCSFTPWRCSSSPLLSSFSAYNMSSGNRVTSSVGGSSGATEVCPSHTPLSSSTLLRYTIAPSEPTMGSPWQTSEESASRRLAALTSYPPSNIRNVAVVAHVDHGKTTLSDVLLRRTGVLKGSVNAGAYTDRLLVERERGITVKSQTCSMFLKYGGSEFLLNLIDTPGHVDFQYEVSRSVRAAQAVLLLVDVAQGIEAQTMSHFHMALDQGLAIIPVFTKMDCVLNDTTVDAALQQLEDSTGLLRSEVVFTSAKEQLGVEALLQAIIERVPSPSGAIGLSDVCQLPPLLPGSTARVAMEAEMVPLRAILLDSWTRECGGGLYRPPSKTSSALSGNVKIDEDKDTVTCLVSVIDGTLTARTNILLYHSQKRYEAREVGVIHPELRPTGALTVGMVGYVVFTRVQREDFSVGETLYTLPTRKFTRGGIAPVPGFRRVHPVVFAGFYPDEGEYVTQLREAVEKLRMNDPAVTVEPLECQALGSGLQLGFLGVLHMQIFQERLLSEFGQRVLVTPPVVQYKYREAAGGDDQPPKPLSVHTWRWLHEGVSCYMEPHVTATVVTPSEYAQIIDGEAQRHYRGKQLDMRVMDDARVLLRYKMPLADMVRGFFTFVKSQSHGYASLEYDELVYEEADLVRVDIVVQKARISALAVICPRHEAPSVGKRIVASLKSNLTRTAVDIPLQALVGSKVVARETVRAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRTVGGVTLDQSVLAAAMGATAL
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MSTAB_DROME
Sequence: MSTSTPVTEEPRSSSQMTISASTQELAELINIHLGDLRPEEPSWRVADSPISGRGIFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCSECRDSTRHDLECKLFRKWKPLESQRIEPRALRILSVVRCFFLDEASRKLLYAMQANMDRYYMQEVQRAADCFEHFPREQDMLDYFYRTICAFNTNAFESRSNVDGHEVLVRALFPLAGLLNHQCTPNAAHHFENGETIVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFICKCVRCQDPTENGTYLSALFCREQGCRGLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSCSVQDMIHFINELCPRFCPSSNYVLIEAKLNVIWRMTRFDHEEYTPEEMGHMDRYREEVLAILHKLGAGECTLKKLITGEIQ
What are the official names of this protein?
SET domain-containing protein SmydA-8, isoform B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: DNLJ_SYNS9
Sequence: MPDQSERATELRNLLNTAAHAYYVLDTPTMEDAVYDRLYQELLELEQNTPSLKTADSPTQRVGGAPAEGFTSVEHRIGLLSLDNAFNRDDLSAWNERLLRAIDRPLGSPLDLVSELKIDGNALALSYRNGVLERAATRGDGQRGEEITANVRTISAIPLRLRLDNPPEWVEIRGEAFIPDNTFAEINAERESRGEALFANPRNACAGTLRQLDPKVVAARRLDFFAYTLHLPTQEQPASQWDALTWLENAGFRVNPNRALCADLADINRFSDHWEQARHDLPYATDGVVVKLNNLVLQDEAGFTQKSPRWAIALKFPAEEAPSRLLRVVVQIGRTGVITPVAEFEPVALAGTSVSRATLHNADRIAELDLHLGDTIVVRKAGEIIPEVVRVLPELRPSSATPVQLPEHCPECGSNLVREGDEVATRCVNSSCPAILRGGLRHWVSKGALDVDGLGSKLIEQLVDQGLVRSIADLYRLDAALLGSLDRMGERSANNLIEALKLSRQRSWARQLYGLGIHHIGEVSAKAITAEFSDSNSLMEAACTAPERITAIYGIGTELAQSLQQWFSNPANQHLLDDLRSQGFRFALDDNDPGRLGAAASEQHLKGLTFVLTGTLPTLSRSEAKERIETCGGKVSGSVSKKTDYLVAGEEAGSKLTKATTLGIKILDEDRLQAMLKDSP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PABN1_ARATH
Sequence: MPVHDEQEHEVYGGEIPEEEEGEMDTEEYEEHGGEEGAAAGDEELEPGSSSRDLEDMKKRIKEIEEEAGALREMQAKAEKDMGASQDPSGGVSAAEKEEVDSRSIYVGNVDYACTPEEVQQHFQSCGTVNRVTILTDKFGQPKGFAYVEFVEVEAVQNSLILNESELHGRQIKVSAKRTNVPGMRQFRGRGRPFRPMRGFMPGVPFYPPYAYGRVPRFRRPMRYRPY
What is the function of this protein?
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product.  Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length.  Increases the affinity of poly(A) polymerase for RNA.  Binds to poly(A) and to poly(G) with high affinity.  May protect the poly(A) tail from degradation.
What are the official names of this protein?
Polyadenylate-binding protein 1, AtPabN1, Poly(A)-binding protein 1, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein I, PABI.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus.
Protein: KR10A_HUMAN
Sequence: MAASTMSICSSACTDSWRVVDCPESCCEPCCCAPAPSLTLVCTPVSCVSSPCCQTACEPSACQSGYTSSCTTPCYQQSSCQPDCCTSSPCQQACCVPVCCVPVCCVPVCNKPVCFVPTCSESSPSCCQQSSCQPTCCTSSPCQQACCVPVCSKSVCYVPVCSGASTSCCQQSSCQPACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGASASSCQPSCCRTASCVSLLCRPVCSRPACYSLCSGQKSSC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 10-10, High sulfur keratin-associated protein 10.10, Keratin-associated protein 10.10, Keratin-associated protein 18-10, Keratin-associated protein 18.10.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 10 family.
Protein: AROB_DECAR
Sequence: MKTVTQTLNVALGERSYPIHIGTDVLSRPELILPFLSQKRVVVVTNTSVAPLYLDELRSGLEKCGIETLPVVLPDGEQYKTWETLNLIFDALLAARCERNTTLIALGGGVIGDMGGFAAACYQRGMPFIQVPTTLLSQVDSSVGGKTAINHPMGKNMVGAFYQPRLVLADLSTLDTLPDRELKAGLAEVIKYGLIRDPDFFVWLEANLEKLLVRDKSALAYAVHRSCANKAEVVAADERESGERALLNLGHTFGHAIETGLGYGEWLHGEAVAAGTLIAAELSCRLGWIDADSVARIEKIFVRSGLPVKAPDLGAARYLELMSHDKKVQDGKLRLVLLREIGKAVVSDAATTAQMVDAIEARCT
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_BURP6
Sequence: MSFDSVPRHALSMRFDLEPPSHASAAHRVAVLLVNLGTPDAPTPRAVRRYLAQFLSDPRVVEIPQLVWQVILRTLILPLRGRASAKKYAAVWLPEGSPLRVYTERQVESVKPLFAANGYRVIVDYAMRYGTPSIADVLAQLKRAGAERVLLLPMYPQYSSSTTATAFDAAFAALGRMRNQPEVRTVRHYADHPAYIHALAEQVRQYWAAHGRPAFDAGDKLVLSFHGVPKRTLDLGDPYHDQCQQTAALLMSALGLTTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRRADVFCPGFTADCLETIEEIGIEVRDAFVHGGGKEFHRIPCLNASPAWIAALGEIAAENLQGWPVRVAMAPEAVS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_STAHJ
Sequence: MNEEQRKAGTINILDERDRKVEKDYSKYFENIYQPPSLKEARKRGKQDINYNRDFHIEDKFEGMGKGRTFLIKTYGCQMNAHDTEVMAGILQALGYTATEDINEADVILINTCAIRENAENKVFSEIGNLKHLKKNRPEALIGVCGCMSQEESVVNKILKSYQNVDMIFGTHNIHKLPEILEEAYLSKAMVVEVWSKEGDIIENLPKVREGSTKAWVNIMYGCDKFCTYCIVPFTRGKERSRRPEDIIEEVRGLARDGYKEITLLGQNVNSYGKDIKDLEYGLGDLLEDISKIDIPRVRFTTSHPWDFTDRMIEVIAKGGNIVPHIHLPVQSGNNAVLKIMGRKYTRESYLDLVNRIKKSIPNVALTTDIIVGYPNETEEQFEETLSLYDEVQFEHAYTYLYSQRDGTPAAKMKDNVPEDVKKARLQRLNKKVGHYSEKAMNQYEGKTVTVLCEGSSKKDDTVLAGYTEKNKLVNFKGPREAIGKLVNVEIDETKQYSLNGTFKEFNDAPLVTN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM7_ARATH
Sequence: MSGRKETVLDLAKFVDKGVQVKLTGGRQVTGTLKGYDQLLNLVLDEAVEFVRDHDDPLKTTDQTRRLGLIVCRGTAVMLVSPTDGTEEIANPFVTAEAV
What is the function of this protein?
Component of LSM protein complexes, which are involved in RNA processing.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay.  The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts.  Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs.  LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mRNAs through the stabilization of the spliceosomal U6 snRNA.  Plays a critical role in the regulation of development-related gene expression.
What are the official names of this protein?
Sm-like protein LSM7, AtLSM7, Protein EMBRYO DEFECTIVE 2816, U6 snRNA-associated Sm-like protein LSM7.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL332_STRP3
Sequence: MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MNMA_CHRSD
Sequence: MSHATGSRAAGATTACKVIVGMSGGVDSSVTALTLLEQGYAVEGLFMKNWDEDDGTEYCTAKEDLADAQAVCDTLGITLHTANFAAEYWDNVFEHFLAEYKAGRTPNPDILCNREIKFKVFLEYAEMLGAEKIATGHYVRQGWRDGHCRLLKGLDANKDQSYFLHAVPEVAIARTLFPVGEMEKSEVRAIAERHGLTTARKKDSTGICFIGERRFSDFLKQYLPAQPGVIETPEGEVIGEHMGLMYYTLGQRQGLGIGGLPNHPDAPWYVAAKDLERNVLIAVQGKHHPLLYTDSLSTEPVEWVAGQPPAPEARLQAKTRYRQQDVACHVRVLEDGGVEARFDEPQRAVTPGQSLVLYDGDICLGGGVIRSTWNHSEPRGDSAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_GALSU
Sequence: MGLNIRVIAPDRIVWNAKAEEVILPTSTGQLGILSGHAPLLTALDIGVMRVRITNTWTSIVLFGGFAEVENDEILILVNGAEEASVINLDKANKELIESSSLLNEAKTNKEKFEATQKLRKAKARVQAANTLTNQSIY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SPC34_CANGA
Sequence: MGESMNSCLEEINGCLDSITSLYFKPPGIFHNAMIRISKDGKETHTLNDKIKNLIKGCDPKEETTLFQLDPVTKSLRRKDGRQALFDYLDKRDLNMKRNRRLGHKDEKPVIHVPNEFYIREHDEELLRDSQRTKRFKAAGHGNDIDSNNTNNTTTALITELFNDDVGLMATMRKKFKENDEIKNLLMALQKGSVILDEKEGISTNNRRRTLFVEDFSTESILKLLDAVLEMFPTEEYKKAAEQYHDVFQELNEESEKLLAEIQLQKDEIEGRLKIESSKDSTTGVQKLIEKERQKIAELESQLRISN
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit SPC34, Outer kinetochore protein SPC34.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC34 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: SMXL8_ARATH
Sequence: MPTAVNVAKQCLTAEASYALEEAVNVARRRGHSQTTSLHAISALLSLPTSVLRDACARVRNSAYSPRLQFKALDLCLSVSLDRIQSGHQLGSDDSPPVSNSLMAAIKRSQAHQRRLPENFRIYQEMSQSQNQNSLSCVKVELRQLILSILDDPVVSRVFGEAGFRSSELKLSIIRPVPHLLRYSSQQPLFLCNLTGNPEPNPVRWGFTVPSLNFNGDLDYRRISAVFTKDKGRNPLLVGVSAYGVLTSYLNSLEKNQTDGMILPTKLHGLTAVNIGSEISDQISVKFDKTYTDTRFHDLGKLAEQGSGPGLLLHYGDLRVFTNGEGNVPAANYIVNRISELLRRHGRRVWLIGATTSNEVYEKMMRRFPNVEKDWDLQLLTITSLKPCLPHNKSSLIGSFVPFGGFFSTTPSELKLPFSGFKTEITGPVSSISDQTQSTLPPWLQMTTRTDLNQKSSAKVVQTKEGLESVCGNKFTSSASASTCSAKSVTTDLNLRVSSVTTGSGLKKHLDSKDFSQPQSVSSYSFDNPRDLNAESFKIIYRRLTDMVSGQDEAARVISCALSQPPKSVTRRDVWLNLVGPDTVGKRRMSLVLAEIVYQSEHRFMAVDLGAAEQGMGGCDDPMRLRGKTMVDHIFEVMCRNPFCVVFLENIEKADEKLQMSLSKAIETGKFMDSHGREVGIGNTIFVMTSSSQGSATTTSYSEEKLLRVKGRQVEIRIETVSSLPMVRSVYGPTSVNKRKLMGLGNLQETKDTVESVKRLNRTTNGVLDLNLPAQETEIEEKYHCEENSNVWLMNLKNHKRLIEVPFKPFDFEGLAEKIKKSVKENFDKCVRSDCLLEVDPKIIERLLAAVYFSDSRKDIKELLENIMSPVFLRIKERYEITTSCVVKLVGRDLDIFLEDQMDLFFVKSQ
What is the function of this protein?
Probable component of a transcriptional corepressor complex involved in branching control.  Regulates cotyledon expansion and lateral root growth, but not germination or hypocotyl elongation.  Promotes auxin transport and PIN1 accumulation in the stem and represses BRC1/TCP18 expression in axillary buds (PubMed:26546447, PubMed:26546446).
What are the official names of this protein?
Protein SMAX1-LIKE 8, AtSMXL8, Protein D53-like 3, AtD53-like 3, Protein D53-like SMXL 8.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THG1_DICDI
Sequence: MANSKYEYVKSFEQPDILLQNVWIVVRIDGRSFHKFTTKHDYAKPNDDRGLSLMNRAALEVCKEFPDIVIAFGESDEYSFVLKKSCNLFERRSSKISSSIVSYFTSQFVYRWKEYFGEHELKYPPTFDSRCVLYPTDENIKDYLSWRQADTHINNLYNTCYWALVLKAGKTPIEAENELRGTFSDGKNEMLFSRFNINYNNLPAEYRKGSVIFKKPVQETNKETGLTKSKKRLVIEHVDIISEKFWKEYPDILASK
What is the function of this protein?
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
What are the official names of this protein?
Probable tRNA(His) guanylyltransferase, tRNA-histidine guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(His) guanylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BURM1
Sequence: MSVSAQSVPTTIACLLGPTASGKTAAALALAARRPIEIVSVDSALVYRDMDIGTAKPTREERARVPHHLIDIIDPADAYSAASFRADTLRLIGEIVARGNTPLLAGGTMLYYKALTQGLNDLPTADPAVRAELDAEAARDGWPALHARLAQIDPATAARLAPNDAQRIQRALEVFMLSGQPMSALLAAPRPADEAAAAYRFVPVALEPSDRAVLHARIAQRFDAMLAAGFIDEVERLRRRDDLHLGLPSMRCVGYRQAWEFLDGDIDYRTMRDKGIFATRQLCKRQITWLRAMPERIVVDCIAPDSTARALDALERVLDGRIAAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRMA_SHEWM
Sequence: MNLAAMDPNTYDAQLEEKRIKLENIFTDFDTPNLEVFSSEQAHYRMRAEFRIWHDGEDMYYYMFDKALNSKVRCDQFLPASKLINEMMPALIAELKPNPLLRHRLFQIDFLSTLSGEILVSLLYHKQLDEQWETEAKSLKERLASKFNVNIIGRARKQKLIFDKDFVVESLQVNGEQLQYHQIENSFTQPNGKVSVKMLEWAIDVTKNSSGDLLELYCGNGNFSIALAQNFDRVLATELAKPSVESAQYNIKINKIDNLQIIRMSAEDFTDAMAKKRSFRRLEGIDLDSYNCNTIFVDPPRAGMDPDTVKLVQGYERIVYISCNPNTLIDNLVELSKTHKITRFALFDQFPYTDHMESGVFLERK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: BIOD_CLOK1
Sequence: MAKGIFIVGTDTDIGKTVVTAGLMHVLRSRGYNAVYFKAALSGALEIDNKLIPSDTKLVSDVSKLEEPYENITPYVYRTGVSPHLAARLENNPMDLDIVKEKYVYLKEKYDFIIAEGSGGIVCPLIDDGRGVYTIGNLIKDLNMSVIIVASAGLGTINHTVLTAKYIENLGIKIEGIIINKYEKDLFYDDNIGMIEKITKLPIVAKLKNIKDMNDNEIEAIRIHSEKAFSAENIIKHMEQL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPCS_DANRE
Sequence: MNSENFRLSEKLVSASYVRQGLDARRGHEQLIRRLLDQGKCPEEGWSESTIELFLNELAVMDSNNFLGNCGVGEREGRVASSLVARRHYRLIHGIGRSGDIAAVQPKAAGSSLLNKITNSVVLDVLKLTGVRSVSSCFVVPMATGMSLTLCFLTLRHRRPKARYILWPRIDQKSCFKSMVTAGFEPVVIENVLEGDELRTNLEEVERKIEEFGAENTLCVHSTTSCFAPRVPDRLEELSVLCAKHDIPHIVNNAYGVQPSKCMHLIQQGARVGRIDAFVQSLDKNFVVPVGGAIIAGFDENFIQEISKIYPGRASASPSLDVLITLLTLGANGYKKLLADRKELYGHLAQELSALAARHGERLLKTPHNPISLAMSLNHLEAHSSSAVTQLGSMLFTRQVSGARVVPLGVQQTVSGHTFSGFMSHSEAYPCPYLNAASAIGITKGDVTVCMKRLGKCLKILKKEKSDPADLEAEDGELEESPQRSTELRV
What is the function of this protein?
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
O-phosphoseryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep-tRNA:Sec-tRNA synthase, SepSecS, Soluble liver antigen/liver pancreas antigen-like, UGA suppressor tRNA-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SepSecS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y013_METJA
Sequence: MPKKKNKLPTEIVLTYKVKHNHDLKNLPDEFIKISQRAIDIIWENINWKEKVVKHRYKIGKKKYKYYTTTRLIPKIPKDNDFKRELRNRLLEGWEFASHYVDGAIKTAYSAIESWKSNYLNVNRKKNKPIFKRPFVRVKTTLMKYDRKNGIIRITIKPRKSI
What are the official names of this protein?
Uncharacterized protein MJ0013.
Protein: HME2_HUMAN
Sequence: MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE
What are the official names of this protein?
Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_MYCSS
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRFGGQVVKAGEIIVRQRGTHFHPGVNVGRGGDDTLFATAPGSVEFGSRRGRKTVNIVPVARPEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LEU3_MYCLE
Sequence: MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREHDAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVVREGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVHKNNVLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDLAAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAHLGEDEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.