PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_XANC8
Sequence: MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTGIGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMAREAGAEGDEVATVIRKALQAALR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MAP2_LACTC
Sequence: MSDAIAKDAVNTSSEKEPVSATPELKTSGSPDAAVSSGDKKKKKKKKKTNNIKNIALLYPDEKYPEGEWMDYHQDFNLQRTTDEEKRYLTRDAENQQRWNDMRKGAEIHRRVRKNLQNKLKPDMTLTEVVNIVENATRKFTGVDENGDHVDRPKSQGVGFPTGVSLNHCAAHFTPNAGDQTVLRYEDVMKVDIGVQVNGYIVDSAWTVAFDPKYDNLLQAVREATNTGVREAGIDVRLTDIGEAIQEVMESYEVELNGKTHQVKPCRNLCGHNIAPYRIHGGKSVPIVKNGDQTKMEEGEHFAIETFGSTGRGFVVPGGEVSHYAKSAEADGLPAPSLSRAKSLLKTIDENFGTLPFCRRYLDRLGEDKYLFALNSLVKHGIVQDYPPLNDVQGSYTAQFEHTILLHPHRKEVVSRGEDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_KLEOX
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAQILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWFDAASGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLSKVRAVCRVPLIASGGAGTMEHFLEAFRDASVDGALAASVFHKQIINIGELKTYLAAQGVEIRVC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_HAES1
Sequence: MRHRKSGRQLNRNSSHRQALFRNLASALVSHEIIKTTLPKAKELRRVVEPLITLAKVDSVANRRLAFARTRNIETVAKLFNELGPRFAQRAGGYTRILKCGFRAGDNAPMAYIELVDRPALAEEAKTE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HSP1_THYCY
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BEX3_HUMAN
Sequence: MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP
What is the function of this protein?
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF.  Plays a role in zinc-triggered neuronal death (By similarity).  May play an important role in the pathogenesis of neurogenetic diseases.
What are the official names of this protein?
Protein BEX3, Brain-expressed X-linked protein 3, Nerve growth factor receptor-associated protein 1, Ovarian granulosa cell 13.0 kDa protein HGR74, p75NTR-associated cell death executor.
What is the protein family that this protein belongs to?
Belongs to the BEX family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
Protein: TMOD_CAEEL
Sequence: MSQAKTDYYSEEKTFSAPSANSQQGTQLPSKVYNKGLKDLEDNDIEGLLSSLSIDELEDLNNDFDPDNSMLPPSQRCRDQTDKEPTGPYKRDNLLKFLEDKAKTEKDWEDVCPYTPGQKRGKVYDSDSGRNSEEPENGKMEMPIEIDLDDDEEELECALVTAPEKDLVDLAGILGMHNVLNQPQYYNALKGKTQDESTGTTFNGIMQSYVPRIVPDEPDNDTDVESCINRLREDDTDLKEVNINNMKRVSKERIRSLIEAACNSKHIEKFSLANTAISDSEARGLIELIETSPSLRVLNVESNFLTPELLARLLRSTLVTQSIVEFKADNQRQSVLGNQVEMDMMMAIEENESLLRVGISFASMEARHRVSEALERNYERVRLRRLGKDPNV
What is the function of this protein?
Acts as the pointed end capping protein which maintains the length and dynamics of the actin filament.  Blocks the elongation and depolymerization of the actin filaments at the pointed end (By similarity).
What are the official names of this protein?
Tropomodulin, Tmod-like protein, cTmd1, Uncoordinated protein 94.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1462_STRPS
Sequence: MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SPCG_1462.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM39_HUMAN
Sequence: MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR
What is the function of this protein?
RNA-binding protein that acts as a pre-mRNA splicing factor (PubMed:15694343, PubMed:31271494, PubMed:28437394, PubMed:28302793, PubMed:24795046).  Acts by promoting exon inclusion via regulation of exon cassette splicing (PubMed:31271494).  Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity (By similarity).
What are the official names of this protein?
RNA-binding protein 39, CAPER alpha, CAPERalpha, Hepatocellular carcinoma protein 1, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Splicing factor HCC1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Concentrated in nuclear speckles (PubMed:8227358). Colocalizes with the core spliceosomal snRNP proteins (PubMed:8227358).
Protein: TAM_PSEAB
Sequence: MVHDLLRDRADLEARWNPSAYMQFARLRQRPVVELLDNIELCCPERIYDLGCGTGIATELLARRWPLAELHGVDSSVEMLEEAARLPIKASWERANLRHWCAERPASLLFAAAVLHFLEDHGKLLPRLLGQLAPGGCLAAHMPNWRDASWYRLMLDALDSAGPGGASLGSPALRYRLHRRNVLSLDNYYRLLAPLTAELDIWETEYLQVVDGNDPIFDWIKVSALRPVLGELDEEARRRFLDRYLELLHRHYPRELDGRTLFPFRRVFIVASLGR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_SORMK
Sequence: MGQVLSEEKPAPLSHEEIVKELANIFAEKCFTSLELYSLKQVFKSLADHEQRVGYLKEGTVAKYLKVPGILDVSAVLFQMASYIAAFPFLEDAPAVLGLEQMVIVITLVTDRYRRVLGKRAADKTKLLFKSLAVYDRKFAKPAVDTPSHSKNAREQIGSDGQGLDNDELVLAAFDALGHVGSKKQQNMPAAHGAMIPGDNFRKLIMLLLLVAPLDGQDSLDSDPDRVTGAGLQSLRTAAESILAAFLDVEQNPGIEYHRFNKVIAGCLPFLFQGLAPLFEHFLFSKELDFHKGKGDTFRSPVMPPEPRQPLLQDTGSIMNASILSQMSFFIPGSFLFRRIRLLYAGDLDGFSMGSFETKVFNWRAPTILLVSGTRLLDESDHHSNGSVPAFWASLPPRRFPPGSSGEGERLAFGVYIFEPWKLTHRECFGGEETILFQLEPIHDLFRASPLNKDYVSFTRPSASTSHAGVSFGCPPPKPSQAYRRSGMIPLGPVSLMLDGSFEYGCFTHDYASSGGAFQTSMVREYNFQERLTLKAWRSGAAAGTRKQGTKQNNGRGKQEKLKLEGESTWGRATLKPTEHY
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAB_BOVIN
Sequence: MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPASTSLSPFYLRPPSFLRAPSWIDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLAITSSLSSDGVLTVNGPRKQASGPERTIPITREEKPAVTAAPKK
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.  Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.  In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity).
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Lysosome. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. Localizes at the Z-bands and the intercalated disk in cardiomyocytes. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: O1613_CONAE
Sequence: MKLTCVLIVALLFLTACQLTTADDSRDKQEDPLVRSHRKMQKSEDPKMAERCSNFGSDCIPATHDCCSGECFGFEDMGLCT
What are the official names of this protein?
Conotoxin ArMKLT2-0311.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAA_PHYAS
Sequence: MKKIIAITGPTASGKTSLSIKIAKKFNLEIINCDSTQIYQQYNIGTAKITKEEMEGVKHHLLDFLPPEEKYSIYHFQKSARAKIKDINNPLFVGGSGLYLKAALFDYELTPKPLMPQNVCEQDLQKMLAIIKEKDPQLVLDTKNPLRIISSYYDIVSGHLRSQKTKKNVPLYSLLIFYLDIDRKELKNRVVLRLEKMLNEGFVEEVKNIQTNFPQANFNIIGYREIKDFLEGKYSITEAKNKICQKTMQYAKRQKTWFKNQLQPVVVDALSPSLEKKVFQLVFDFLHKRS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AAS_SALCH
Sequence: MLFGFFRNLFRVLYRVRVTGDVQALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDEAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSAEKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_SINMW
Sequence: MAKVIGIDLGTTNSCVSVMDGKDAKVIENAEGARTTPSMVAFTEDGERLVGQPAKRQAVTNPENTLFAIKRLIGRTFEDPTTQKDKGMVPYKIVKADNGDAWVEAHDKSYSPSQISAMILQKMKETAESYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLDVLRIINEPTAAALAYGLDKKEGKTIAVYDLGGGTFDISVLEIGDGVFEVKSTNGDTFLGGEDFDMRLVEYLASEFKKEQGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADASGPKHLTMKLSRAKFESLVDDLIQKTIAPCKAALKDAGVSAAEIDEVVLVGGMTRMPKVQETVKQLFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQVFSTADDNQSAVTIRVSQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVQVSAKDKGTGKEHQIRIQASGGLSDAEIEKMVKDAEANAEADKKRREGVEAKNQAESLVHSSEKSLQEHGDKVSETDRKAIEDAIAALKSAVEASEPDAEDIKAKTNTLMEVSMKLGQAIYEAQQTESAHADAAADAKRSGDDVVDADYEEVKDEDDRKRSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FUMH_YEAST
Sequence: MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK
What is the function of this protein?
Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:3040736, PubMed:11585823, PubMed:1587456, PubMed:20231875).  In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH (PubMed:1587456, PubMed:20231875).  In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate (PubMed:20231875).
What are the official names of this protein?
Fumarate hydratase, mitochondrial, Fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cytoplasm. Nucleus. Note=Mitochondrial, cytoplasmic and nuclear forms are derived from a single translation product and not by alternative initiation of the transcript (PubMed:11585823). The mitochondrial transit peptide is cleaved by the mitochondrial processing peptidase, promoting mitochondrial targeting of around 70% of the proteins (PubMed:11585823). The remaining 30% of the processed proteins localize in the cytosol: they probably undergo rapid folding into an import-incompetent state, leading to retrograde movement of the processed proteins back to the cytosol through the translocation pore (PubMed:11585823). Translocates from the cytosol to the nucleus in response to DNA damage (PubMed:20231875).
Protein: TAL_BARBK
Sequence: MKFFVDSANCEDIQELQNLGLVDGVTTNPSLILQSGRNILDVIQEICSLVEGPVSAEVAATDFDTMMKEAAVLAKIANNICIKLPITLDGLKACKALSEQELKTNLTLCFSATQALLAAKAGATFVSPFIGRIDDCGTNGIDLLHEIRTIYDNYGFATQILAASIRTTTHVKEAALSGADVATVPPKVLKSLAAHPLTDKGLQTFLTDWAKTGQKIA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP3_ARATH
Sequence: MASKALVLLGLFAVLLVVSEVAAASSATVNSESKETVKPDQRGYGDNGGNYNNGGGYQGGGGNYQGGGGNYQGGGGNYQGGGGRYQGGGGRYQGGGGRYQGGGGRQGGGGSGGSYCRHGCCYRGYNGCSRCCSYAGEAVQTQPGH
What is the function of this protein?
Regulates the function of the receptor protein kinase WAK1, and namely the phosphorylation of OEE2.
What are the official names of this protein?
Glycine-rich protein 3, AtGRP-3.
What is the protein family that this protein belongs to?
Belongs to the GRP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: VIRC2_AGRFC
Sequence: MGIRKPALSVGEARRLAAARPEIVHPSLPVATQNSTLPQPPENLDEEDRRPAPATAKRCHSSDQQSMLTVDALSSTTAPEKIQVFLSARPPAPEVSKIYDNLILQYSPSKSLQMILRRALGDFENMLADGSFRAAPKSYPIPHTAFEKSIIVQTSRMFPVSLIEAARNHFDPLGLETARAFGHKLATAALACFFAREKATNS
What are the official names of this protein?
Protein virC2.
Protein: YQHA_ECOLI
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZNUC_RICCN
Sequence: MQKPIIEFRNVSKKFGNKLPINNVSFTVKKNNITTLIGPNGAGKTTIVRLMLGLEKPTSGEIIIDPKLKIGYVPQKFGLTPDLPITVKNFLELLAPSNFNNNIKEINSFIDLEHIKDQEISKLSGGQFQKVVLACSIVNNPDLIILDEPLQSLDVTSQQEFYQLINLIRKKLNITVFMISHDLFTVIKNSDQVICLNGHICCSGIPNEITPNSEFSNALSALGFYTHHHDHKH
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: H2A4_CHICK
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTDSHKAKAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A-IV.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYL_SHIFL
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALQAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOS3_DROME
Sequence: MSATSTIVMPGERIAAIEELAKSKRVILGPGLRRLDDTVVASKAGPLRHKEPGTFWVDNYQRRYIPARGDLILGIVRAKAGDLYRVDIGATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNASADIEPELVCVNSVGKSGKLGVLTDGFFFKCSLNLGRMLLRENCPVLAALTRELPYEIAVGVNGRIWLKAHSLKETVALANAISALEQSGCAEIDKICGNLGDFLQA
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events (By similarity).  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts such as antisense RNA species, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm (By similarity).  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs (By similarity).  The catalytic inactive RNA exosome core complex of 9 subunits is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity).  Required generally for normal embryonic and neuronal development (PubMed:32645003).  Also plays a critical role in the maintenance of neuronal function in mature flies by controlling the levels of specific mRNAs such as the synaptic regulator Arc1 (PubMed:32645003).
What are the official names of this protein?
Exosome complex component RRP40, Ribosomal RNA-processing protein 40.
What is the protein family that this protein belongs to?
Belongs to the RRP40 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: CH60_ECOLI
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
(Microbial infection) Essential for the assembly of several bacteriophages.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60, GroEL protein.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Uniformly located in the cytoplasm (PubMed:20094032). Exclusively localized in foci, usually near 1 cell pole in mid-to-late exponential phase (PubMed:22380631); polar localization depends on the minCDE operon. Foci form near midcell (Probable).