PharMolix/UniProtQA huggingface dataset:
Protein: RS13_CALS4
Sequence: MARIAGVDLPRDKRVEIALTYIYGIGRSRSKEILAKAGVNPDTRVRDLTEDEVSKLREIIEKEYKVEGDLRKEVAMNIKRLIDIGCYRGIRHKLGLPVRGQRTRTNARTRKGPRKTVAKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RPOZ_CLOB8
Sequence: MNNSMISPSVVDLLEKIHDRYSLVILTSKRARQIIEGAEPQISIKSNKPLTIAINEVDQDAVEFEILEEGLK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IF3_CHRVO
Sequence: MSAIAQEREARINGEITAREIRLVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAKQKQKQVQIKEIKFRPGTDDGDYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALLKRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_YERPP
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQPTTY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBD_RUEST
Sequence: MSTAALLIPAMILDAAFGEPKWLWSRLPHPAVLMGKLVQALDDRLNEGDGRQVKGVIAVAVLVFVGLLLGWILSWFGSLVSVLIAAILIAQRSLIDHVRAVATGLQNDLDAGRSAVAMIVSRDTATMTGPQIARSAIESGAENFSDGVIAPAFWFLVAGLPGLLIYKLINTADSMIGYRTEAYEDFGWAAARLDDVLNILPARLSALLIALVTGRAGDWGEISADARKHRSPNAGWPEAAMARALGVALAGPRSYDGEMRPFAWVNASGSKSASAHSITRCCEVLWKSWGLALVLVVALGLLF
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMH_LEGPA
Sequence: MRRGLLLLNLGTPDNADIRAVKLYLREFLTDKRVIDLPTIPRYILVYCLILPFRSPKSAQAYQSIWTEKGSPLLYHSQNLVTKLQSSLKDEYKIALGMRYGTPSITTALAELKDCHSLTILPLFPQYSSAATGSAIEKTLSYLANQEIIPSIKIIRDFYQRPEYIQAQAKIMKPYIKDNFHVLFSYHGIPERHIHKSGCDTLCPQTCTPIYDKNQACYRAQCYQTSLLLAKELQLGTHQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVVSCPSFVADCLETLEEIGIRAKEQWEKLGGEQFILTPCMNDHPEWIKAIHSIVNEQI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTR_MOUSE
Sequence: MRTLSLLTLLALAALCLSDLTDATPTGPESDKAFMSKQEGNKVVNRLRRYLGASVPSPDPLEPTRELCELDPACDELSNQYGLKTAYRRIYGITI
What is the function of this protein?
Binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin-related protein, Gamma-carboxyglutamic acid-containing protein 3, Nephrocalcin, OC-X.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_COXBN
Sequence: MKVRASVKRMCRNCKVIRRNGVVRVICSDARHKQRQKGGK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: BPT_CHRSD
Sequence: MSSNTPSQLTRDLRFFLTVPHGCSYLPDREATTLFLDPQEQPGQGVYDALALLGFRRSGRHLYRPHCEGCRACISVRIPVEDFTPKRTQRKLISRNVDLETRMLPAAFYEEHYALYARYIRTRHADGDMYPPSHEQYRTFLTLDHPYARLIEFRLQGQLLGVAATDLLSHGVSAIYTFFDPSPAFERRSLGTYAILHQIELARRLGRPHVYLGYWIRQCRKMSYKQDFEPLEYLDGRHWRRQIPLVE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACD_STAAT
Sequence: MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: AROQ_BORPD
Sequence: MAQQILVLHGPNLNLLGSREPHLYGSLTLAQINQGLETLAAQLGVGLTAWQSNHEGALVERIQAARQDGTDFIIINAAAYTHTSVAVRDALAAVAIPFIEVHLSNLYKREPFRQHSYLSDLAVGLVCGLGADGYEAAVRYAARH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: NMNA2_BOVIN
Sequence: MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPRNETSQPIYQNNNAPSKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
What is the function of this protein?
Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity).  Axon survival factor required for the maintenance of healthy axons: acts by delaying Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons (By similarity).  Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP.  Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency.  Cannot use triazofurin monophosphate (TrMP) as substrate.  Also catalyzes the reverse reaction, i. e.  the pyrophosphorolytic cleavage of NAD(+).  For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively.  Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+).  Also acts as an activator of ADP-ribosylation by supporting the catalytic activity of PARP16 and promoting mono-ADP-ribosylation of ribosomes by PARP16 (By similarity).
What are the official names of this protein?
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2, NMN/NaMN adenylyltransferase 2, Nicotinamide mononucleotide adenylyltransferase 2, NMN adenylyltransferase 2, Nicotinate-nucleotide adenylyltransferase 2, NaMN adenylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm. Cell projection, axon. Note=Delivered to axons with Golgi- derived cytoplasmic vesicles.
Protein: PRSA_STAA1
Sequence: MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHIIKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TRA2_PSEFL
Sequence: MAAQRVAMRNIKECLRLKFEGGLSHEKIARALQLSKGVVSKYVTAAAETGMEWPALAVLDEVALAAALLPTARVRQTRGERVLPDLITIHRELRRKGVTLQLLWEEYVAAHPEQPTYRYTQFVEHYRRYASTLKRSMRQQHRAGEKLFIDYAGPTLPVIDPATGEISRAHIFVAALGASNYTYACATPGETQVDWLTALGQAFSYFGGVSEMVVPDNPRALIAHPDRYEPGLNRAALECARHYDTVMLPARPRKPQDKAKAEVAVQVVERWIMRVRHQQFFSLHALNQAIAKLLEDLNQRPFKKLDGCRREWFERLDQPVLRPLPQHPYEVVTFKRCKVNIDYHIEVNGGFYSVPSALARQSVDVRLSAHTVEVLHGNRRVASHLRLQRRGAYSTQSEHMPASHKAHREWTPQRLLDWGERIGPQTRQIVEHQLTHKPHPEMGYRACLGLLSLARQYGNARLEAAASRAVQLRALNGRTVRNLLKQGLDQQPLPKPATPAAQPSSHENVRGADYYTQEELFDDDPTHPEPIAPTAAGRHGPSTGRTMDAAGQPQPELR
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Putative transposase for insertion sequence IS1162.
What is the protein family that this protein belongs to?
Belongs to the transposase IS21/IS408/IS1162 family.
Protein: YVAG_BACSU
Sequence: MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQAYPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFLSSPLSSAINGAALRADGGLVRSVF
What are the official names of this protein?
Uncharacterized oxidoreductase YvaG.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CAN1_RABIT
Sequence: RESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPRELVGQPALHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKRAGTQELDDQIQANLPDEQVLSAEEIDENFKALFRQLAGEDLEISVRELQTILNRITSKHKDLRTKGFSMESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLAIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  Proteolytically cleaves CTBP1.  Cleaves and activates caspase-7 (CASP7).
What are the official names of this protein?
Calpain-1 catalytic subunit, Calcium-activated neutral proteinase 1, CANP 1, Calpain mu-type, Calpain-1 large subunit, Micromolar-calpain, muCANP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: HIS4_CYTH3
Sequence: MIQIIPAIDIIDGKCVRLTQGDYNQKKEYHSNPVEVAKMFEDAGIQRLHLVDLDGAKKKQIVNYKVLENITAATKLSVDFGGGLQSDEDLKIAFDAGARQITAGSIAVKNPEKVQHWLTQFGKECIILGADTKSGMIAVHGWQETSDLSIQQLMNQFIPFGISYSICTDVAKDGLLQGPSFDLYKQLNEEFKQINWIASGGVAELADIEKLNDMGIYGVIVGKAFYEGRITLQQLAQFNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLEA_XANCP
Sequence: MLFQNVSIAGLAHIDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDANIGIEKIGLLINTSVSRDYLEPSTASIVSGNLGVSDHCMTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKTLERMTSPDVTEEEFRNELAALTLGCGAAAMVMARSELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKLAQKTFVAAKQVLGWAVEELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRIALLGIGSGLNCSMAEVVW
What is the function of this protein?
Involved in olefin biosynthesis (PubMed:21266575, PubMed:22524624, PubMed:27815501, PubMed:28223313).  Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (PubMed:21266575, PubMed:22524624, PubMed:27815501).  Is active with fatty acyl-CoA substrates that ranged from C(8) to C(16) in length, and is the most active with palmitoyl-CoA and myristoyl-CoA (PubMed:21266575).
What are the official names of this protein?
Acyl-CoA:acyl-CoA alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. OleA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUS6_ORYSJ
Sequence: MAVGLRRSDSIADMMPEALRQSRYQMKRCFQRYVSQGKRLMKRQQLLDELDKSVDDKADKDQLLQGFLGYVISSTQEAAVLPPFVAFAVRMNPGIWEFVKVHSANLSVEQMTPSDYLKNKEALVDDKWGAYDDDSQLEVDFGALDLSTPHLTLPSSIGKGAHLVSRFMSSKLTDNKKPLLDYLLALSHRGDKLMINDILDTVDKLQTALLLAEVYVAGLHPDTNYSEFEQKFQEWGLEKGWGDTAETCKETLSSLSEVLQAPDPINMEKFFSTVPCVFTVVIFSIHGYFGQEKVLGMPDTGGQVVYILDQVRALEDELLQRIKQQGLNATPKILVLTRLIPEAKGTKCNVELEPIENTKHSNILRVPFKTEDGKVLPQWVSRFDIYPYLERYAQDSSVKILEILEGKPDLVIGNYTDGNLVASLLTSKLGVTQGTIAHALEKTKYEDSDIKWRELDHKYHFSCQFTADMIAMNTSDFIIASTYQEIAGSKEKPGQYESHYAFTMPGLCRYATGINVFDPKFNIAAPGADQSVYFPFTQKQKRLTDLHPQIEELLYSKEDNNEHIGHLADRSKPIIFSMARLDKIKNITGLVEWYGQNKRLRDLVNLVIVGGLLDPSQSKDREEIEEINKMHSLINKYQLVGQIRWIKGQTDRVRNGELYRCIADTKGAFVQPALYEAFGLTVIEAMNCGLPTFATNQGGPAEIIVDEVSGFHINPLNGKEASDKIADFFQKCKEDLIYWSKMSTAGLQRIYECYTWQIYATKVLNMASIYGFWRTLDKEERQAKQHYLHMFYNLQFRKLAKNVPTLGEQPAQPTESAEPNRIIPRPKERQVCPFLRNLLKKETGNN
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase 6, OsSUS6, Sucrose-UDP glucosyltransferase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: RS16_CLOB6
Sequence: MAVKMRLKRMGAKKAPFYRVVVADSRSPRDGRFVEEIGYYNPITEPSTIKLDEEKVQKWIKNGAQPTDTVKKLIEKAGISVK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ITA2_HUMAN
Sequence: MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS
What is the function of this protein?
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
What are the official names of this protein?
Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GCSP_RHIEC
Sequence: MTTPTEFQFTDYQPYDFANRRHIGPSPAEMAEMLKVIGYNSLEGLIDATLPPAIRQKAPLVWGAPMTEREALDKLRETANKNKVLVSLIGQGYYGTITPPVIQRNILENPAWYTAYTPYQPEISQGRLEALLNYQTMVCDLTGLDIANASLLDEATAAAEGMAMAERVAKSKAKAFFVDADCHPQTIALIRTRAEPLGWSVIVGNPFTDLDPVDVFGAIFQYPGTHGHVHDFTGLIARLHQAGAISVVAADILALTLLKSPGEMGADIAVGSSQRFGVPVGYGGPHAAFMAVRDAIKRAMPGRLVGVSVDARGNRAYRLSLQTREQHIRREKATSNICTAQVLLAVMASMYAVFHGPDGIKAIAQQVHQKAVLMAKGLEKLGYKVEPESFFDTITVDVGHMQGLILRAAVAEGVNLRKVGETKIGMSLDERTRPATLEAVWRAFGGNFTIADFEPSYRLPKALLRTSEYLSHPIFHMNRAESEMTRYIRRLSDRDLALDRAMIPLGSCTMKLNATAEMLPITWPEFSDIHPFVPADQALGYREMLDDLTEKLCAVTGYDAFSMQPNSGAQGEYAGLLTIRNYHIANGEGHRDVCLIPTSAHGTNPASAQMVGMKVVVVKVRENGDIDMEDFRAKAEEHAANLSCCMITYPSTHGVFEETVKEICELVHKHGGQVYLDGANMNAMVGLSRPGDIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPHLPGHPETDGRPGAVSAAPFGSASILPISWSYCLMMGGEGLTQATKVAILNANYIATRLKGAYNVLYKSKTGRVAHECIIDTRPLVDSSGVTVDDVAKRLIDCGFHAPTMSWPVAGTLMIEPTESETKAELDRFCEAMLAIREEARAIEDGRMDKTNNPLKNAPHTVEDLVGEWDRPYSREQACFPPGAFRVDKYWSPVNRVDNVYGDRNLICTCPPVESYAEAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RNPH_ALTMD
Sequence: MRPSGRTASQIRPVTITRQYTCHAEGSVLVEFGNTKVLCNATVEEGVPRFMKGQGKGWVTAEYSMLPRATHTRSGREAARGKQGGRTLEIQRLIARSLRAALDLKLLGENTITLDCDVIQADGGTRTASITGACVALVDALTYMRSKGIIKTNPLKHMIAALSVGIYEGTPIADLEYTEDSEAETDMNIVMTETGKLIEVQGTAEGEPFSFEELDELLKIGKHGLRELFDIQKAALA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SMAL1_CAEEL
Sequence: MVLTDEQRQAIAKKREEAIRRAAAYREREMQAAANATASTSSAAPPAPPKPVIPVMFSQNRQNFQPMKPTMNNSTKQSTINNYIKQVQKPEPTSLIKPTIGVKLKLDIGDRIKIEFYPFHSAVIDLIKQVPSRNYDPAKRSWTVASSDHITISNILKNATAVKVELEPLPQNIIGLTNFKPKAAPSDLNTVMDPSLIERLFPYQKEGVIFALERDGRILLADEMGLGKSVQALTIARYYKADWPLLIVCPASVKGAWKKQLNTFFPIIHRIFIVDKSSDPLPDVCTSNTVAIMSYEQMVLKHDILKKEKYRTIIFDESHMLKDGKARRTKVATDLSKVALHVILLSGTPALSRPSELFTQIRLIDHKLFTNFHEFAIRYCDGKQGRFCFEAKGCTNSEELAAIMFKRLMIRRLKADVLKDLPEKRREVVYVSGPTIDARMDDLQKARADYEKVNSMERKHESLLEFYSLTGIVKAAAVCEHILENYFYPDAPPRKVLIFAHHQIVLDTIQVEVNKRKLGSIRIDGKTPSHRRTALCDSFQTDDNIRVAVLSITAAGVGITLTAASVVVFAEIHFNPGYLVQAEDRAHRVGQKDSVFVQYLIAKKTADDVMWNMVQQKLDVLGQVSLSSDTFRTADKMHLRFNDAAQPGIAEYLKKTPDTTIDEWEDPVEEKEDDDLEIICDSPAPKRIKN
What is the function of this protein?
ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA.
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_STRPI
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFAKNLLSAKRELTYCSVCGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHGLYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLLKPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL2_PYRAE
Sequence: MGKRILVQRRGRGGSQFRSPSWKRDGPVRYPPLGVISGKGYVVDILHEPGLNAPVAKIVTENGVEFFNYAAEGLYVGQVVEIGKGASPKTGNIMILGEIPEGTMIFNVEKRAGDGGKFARAGGTYAVVIGQKPEENKTIIRLPSGRTVEVDSRGRATVGIVAGGGRIEKPFLKAGKKYHRARAKAWKYPTVRGKAMSPYAHPHGGGSHQKGGTPVPKTAPPGQKVGFIGSRCTGRGCVRARAQQKQ
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MENH_YERPY
Sequence: MTTLACQKLAPHPESPRHQHAGPWLVWLHGLLGSGQDWLPVAQLCGDYPSLLIDLPGHGQSVSLSADGFADISRQLSQTLQANGIREYWLAGYSLGGRIAIYHACYGRHHGLQGLLVEGGNLGLENAELRQARLQQDRQWAQRFRQEPLPQVLDDWYQQAVFADLDPQQREQLVLLRADNHGTAVAEMLEATSLGHQPWLLPALQRLNVPYTYLCGDRDHKFLQLAQQYRLPLHTLARAGHNAHRANPGAFAAQVLAFLSQSSCLPPSSLSR
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: Y1837_VIBA3
Sequence: MNIDVVLLLKQNPILLIFVVLSIGLAIGKIRFGSLQLGNSIGVLITSLIMGHLGFSFNADALTIGFMLFIYCVGIEAGPNFFGIFFRDGKHYLILSLVVLSTAIALTYFCSEYLGLGFGLSAGMMAGALTATPILVGAQDALNSGLAEVPRNMDLGLVIENLSVGYAMAYLVGLISMIMFARLIPKLQKVNLHDSAEQIAQERGLGTSGQRKVYLPIIRAYRVGPELITWTDGKNLRELGIYRQTGCYIERIRRNGILAHPDGDAILQEGDEIALVGFPDSHARLDPSFRNGKEVFDRNLLDLRIVEEEIVVKSDNIAGKRLSDLNLSEYGCFLNRVVRAQIEMPMDLNIVLSKGDVLQVSGEKSRVHGLAEKIGFISIHSQMADLTAFCSFFILGILFGLITMTFGQVSFGLGNAVGLLLSGIMLGFLRANHPTFGYVPQGALNMVKDLGLMFFMVGIGLSAGGKIFEHLTQVGPQVIGIALIVSVLPVFFAYLVGAYALKMNRALLFGAIIGARTCAPAMDIVNDHARSTIPALGYAGTYAIANILMTLAGTFIIIIS
What are the official names of this protein?
Putative transport protein VS_1837.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.