PharMolix/UniProtQA huggingface dataset:
Protein: ADRE_PENRO
Sequence: MTQAQNYVIPPGSKVLVTGANGYIASHIVKALLDLGYLVRGTVRTPMPWLAEYFERQCGLGRFELIVVSDFQQPDAFDESVKGVSGVIHVAQGLPSSTAAETVKSATAYTVNGVINLFKAASTQRTIQRVVLTSSIVAAGYPTGKGFKLDADSWDESLEQASKDGTTVPIYRACKIEGERQAWKWVEKNQPHFELNSVLPWLTLGKILHPNIGGSTMGYVSGLLRGDTTPFKFLPLPWFVDVEDTARLHAIALLNPSVRSERLFATAAPFTWGDVIEILKRIQPNNARIPAAPIQEEPTLGDVVPAARAEKLLRETFGQLGWTPLEVSLESGIARE
What is the function of this protein?
Ketoreductase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (PubMed:28529508).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (By similarity).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (By similarity).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (By similarity).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (By similarity).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (By similarity).
What are the official names of this protein?
Ketoreductase adrE, Andrastin A biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: H18A2_CYRHA
Sequence: MKLSIIIIVTSLVIAVVAFPSKDSKAIENDKTEQRMEIVVQETARACSKQIGDKCKRNCECCGKTVVCGTIYVGGKEVNQCMDKTSDNAILNGLGKGMNFIENTFSFCV
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVIII.2, HNTX-XVIII.2, Peptide F7-35.67.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APOA4_PIG
Sequence: MFLKAVVLSLALVAVTGARAEVNADQVATVMWDYFSQLGSNAKKAVEHLQKSELTQQLNTLFQDKLGEVNTYTEDLQKKLVPFATELHERLTKDSEKLKEEIRRELEELRARLLPHATEVSQKIGDNVRELQQRLGPFTGGLRTQVNTQVQQLQRQLKPYAERMESVLRQNIRNLEASVAPYADEFKAKIDQNVEELKGSLTPYAEELKAKIDQNVEELRRSLAPYAQDVQEKLNHQLEGLAFQMKKQAEELKAKISANADELRQKLVPVAENVHGHLKGNTEGLQKSLLELRSHLDQQVEEFRLKVEPYGETFNKALVQQVEDLRQKLGPLAGDVEGHLSFLEKDLRDKVNTFFSTLKEEASQGQSQALPAQEKAQAPLEG
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLK_ECOLC
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What is the function of this protein?
Not highly important in E. coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMC_HAEIN
Sequence: MKAFFNDPFTPFGKWLSQPFYVHGLTFLLLLSAVIFRPVLDYIEGSSRFHEIENELAVKRSELLHQQKILTSLQQQSESRKLSPELAAQIIPLNKQIQRLAARNGLSQHLRWEMGQKPILHLQLTGHFEKTKTFLSALLANSSQLSVSRLQFMKPEDGPLQTEIIFQLDKETK
What is the function of this protein?
Involved in transformation (competence for DNA uptake).
What are the official names of this protein?
Competence protein C, DNA transformation protein ComC.
Protein: FUCM_SALG2
Sequence: MLKTISPLIPPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIRADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDIVRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHO1_YEASB
Sequence: MSISSKIRPTPRXPSRMATDHSFKMKNFYADPFAISSISLAIVSWVIAIGGSISSASTNESFPRFTWWGIVYQFLIICSLMLFYCFDLVDHYRIFITTSIAVAFVYNTNSATNLVYADGPKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPYQNNVYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFENTQPNTSEAVNLHLNXLQQRINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQNEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane.  PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures.  Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress.  Involved in the regulation of the mating pathway.  May be a receptor that feeds into the pseudohyphal growth pathway (By similarity).
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1, Suppressor of SUA8-1 mutation, Synthetic high osmolarity-sensitive protein 1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud. Bud neck. Cell projection. Note=Localizes at the tip of the mating projection during conjugation.
Protein: DAPH_ENTFA
Sequence: MDAYEIIQYIGDAKKQTLVKVTLKGQLKEVTFPETIKVFNNCKTGTLFGDWADVKPFLEANKEKIEDYVVENDARNSAIPFLDLKDINARIEPGALIREKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKHCHIGAGTVLAGVIEPPSAAPVVIENEVVIGANAVVLEGVRVGEGAVVAAGAVVVEDVPAHTVVAGVPAKVIKQIDDKTKSKTEILEELRKL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: NPL4_NEOFI
Sequence: MAAARPIILRFESRNGQFRLSVSPQEQFPLLQEKILENLPKDVEPSSLVLSNKPIGTGGQERQLKDLAGVSIERVGLKHGDKLFIGYQDKQASQAAPAHKHVTADVSRRLNGAPVPETETVTFHPPTSPSATIKNPWEVVQQSPLDDMLDKKDGKIYRPRDPKMCNHGPKGMCDYCMPLEPYDPKYLAEKKIKHLSFHSYMRKVNATTNKAELKSSFMPPLNEPYYRVRRDCPSGHPPWPEGICTKCQPSAISLQPQEFRMVDHVEFASPDLINSLLDFWRKSGAQRLGFLYGTYEEYTEVPLGIKAVVQAIYEPPQVDEIDGITLHEWPNEKEVDEVARQCGLEKVGVIFTDLLDAGRGDGSVVCKRHIDSYYLSSLEIAFASRMQAKHPKATKWSRTGRFGSNFVTCVLSGDEEGAITVSSYQASISAVEMVRADIVEPSAEPSVMLVQSEDDDTDNKSRYIPEVFYRKINEYGVSAQQNAKPSFPVEYLLVTLTHGFPTEASPMFSASTFPIENREVIGESQELRHVAKKLVSHGDPDKAIREVSDFHLLCFLHSLSMFSKEEEALLCRVATTHDPTEGLKLLNTPGWATLVTVLQESGERPPKRPWLNPADPPRPLSQQGKRHLSSRPESPKSESEQLAKRFKGASLE
What is the function of this protein?
Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus.  Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
What are the official names of this protein?
Nuclear protein localization protein 4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane.
Protein: TX1C_DINQU
Sequence: LRPDDLSDT
What is the function of this protein?
The synthetic peptide has no antimicrobial activity against strains of Gram-positive or Gram-negative bacteria, or against yeasts and other fungi.
What are the official names of this protein?
U1-poneritoxin-Dq1c, U1-PONTX-Dq1c, Peptide Dq-1030, Poneratoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: CHS8_MEDSA
Sequence: MVSVSEIRTAQRAEGPATILAIGTANPANCVEQSTYPDFYFKITNSEHKTELKEKFQRMCDKSMIKRRYMYLTEEILKENPSVCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIVCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVWTAQTIAPDSEGGIDGHLREAGLTFHLLKDVPGIVSKNINKALVEAFEPLGISDYNSIFWIAHPGGPAILDQVEQKLALKPEKMKATREVLSEYGNMSSACVLVILDEMRKKSAQDGLKTTGEGLEFGVLFGFGPGLTIETVVLRSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 8, Naringenin-chalcone synthase 8.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: ILF2_HUMAN
Sequence: MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE
What is the function of this protein?
(Microbial infection) Plays a positive role in HIV-1 virus production by binding to and thereby stabilizing HIV-1 RNA, together with ILF3.
What are the official names of this protein?
Interleukin enhancer-binding factor 2, Nuclear factor of activated T-cells 45 kDa.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: PNP_FRATM
Sequence: MKIFREVFELGNKEIILETGGMARQADGSVTVSCGNNIVLVTTVVKKSVADGTDFFPLSVHYLEKTYAAGKIPGGFLRREGRPSEEQILISRLIDRSIRPSFPDGFFNEIQIVATVLSYDGAFSPDILALIGASASLAISGAPYDDVVAGVRVGYTNGKYILNPNKQDLRDSDLDLVVSGTDDAILMVESEANSLPESVMLGGILYAHKHLKTIINSINRLAKVASKPRMEYSIYQINKFLKSQIKSQFFGEIKNAYTIASKQERNLKLNAIRKNVLEYIFSSDVDGNEYTEKEILEAFHDIEKDLVRSNILEGKPRIDGRCTETIRPINVKIGVLPGVHGSALFTRGETQALVVTTLGSDRDAQLVESLDGIEKCRYMLHYNFPPYSVGECGMVGMAPKRREIGHANLAKRATQAVFPNEEAYPYVVRVVSEILESNGSSSMATVCGSSLSMMDAGVPIAEPVAGIAMGLIKDGAKYAVLSDILGDEDHLGDMDFKVAGTRYGVTALQMDIKIKGISREILEQALEQARVGRLHILGIMNEVIKEHKEAVSDVAPQIHVMNINPAKIKDVVGRGGATVKGIVEKTGAQIDTSDSGEVKVFAKDKKSMDMAVAMIEEIVAEVEEGQVYKGKIVKLLDSGVFVNLLGSQDGYLPFSEIEQAGMKTNSLVEGQGLEVLVQNIDRGGRVKLSLVAR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_ROSDO
Sequence: MNAATKLPGDVGPIHFVGIGGIGMSGIAEVLLNHGYRVQGSDLKPTRITRRLEELGARVFVGQRPENIEDAEVIVISSAIKPGNAELDAARARGLPIVRRAEMLGELMRLKSNIAVAGTHGKTTTTTMVATLLDAGEFDPTVVNGGIIHAYGSNARKGEGEWMVVEADESDGTFNRLPATIAIVTNIDPEHMEHWGDFDTLRQGFLDFVSNIPFYGVAVCCTDHPEVQALVGKITDRRVITYGFNAQADVRAVNLRYAGGVAYFDVALQAEGTVIEGCSLPMPGDHNVSNALSAIAVARHLGMKAEVIKTALAAFGGVNRRFTRVGEIDGVTIIDDYGHHPVEIAAVLKAARQATEGRVIAVHQPHRYSRLSSLFDDFCACFNDADVVGIAEVYAAGEDPIPGAGRDDLVAGLIRHGHRHARAVVGEDDLERLVREQTRPGDMVVCLGAGTISAWANGLPARLQKGAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZPBP2_RAT
Sequence: MLAWALLSAVLWSLAGVGSARSSLFSNEGFVYGTVGHPVKIYVKLHQTSPVLVCMDIDRASKETVDPIYLWIGPNENTLTGSSQINITNIGELVLKDFMESLSGHYSCTLSYKIVKAETQEETSLKKKYDFLVFAYREPDYSYRMAVRFTTKSCVGRYNDLLFRLLKKILDNLISDLLCHVIEPSYKCHSVKIPERDFVYELFVAFQVNPFAPGWKSMCNSSMDCEDVTNHNILKARDRIEEFFRSQAYILHHHFNITVPAMHFVDHSFQVTRIDNCRPGFGKNEGLHSNCASCCVVCSPGTFSPDMDVTCQTCVSAHVYGAKACP
What is the function of this protein?
Is implicated in sperm-oocyte interaction during fertilization.
What are the official names of this protein?
Zona pellucida-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the zona pellucida-binding protein Sp38 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Released after the acrosomal reaction.
Protein: PSBI_LOLPR
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ISPG_SHESM
Sequence: MYNETPIKRRPSTRIYVGNVPIGDGAPIAVQSMTNTKTTDVEATVAQIRALEKVGADIVRVSVPTMDAAEAFKVIKQSVSVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIRQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELERRLEDVTTAMDVSIIGCVVNGPGEALVSHIGLTGGHRKSGYYDEGERQKERFDNDNLVDSLEAKIRAKASQMANRIQVKDTTE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SFSA_METEP
Sequence: MRFPTPLIEGRLVRRYKRFLADVTLADGTMVTAHCANPGAMLGLNAEGFRVLLSPSTNPSRKLGYSWELVEAELPGGLQWVGINTARPNALVAEAFRENKLTPLIGYETLRPEVAYGKASRVDFLTSGGGLAPCHVEVKNCHLMRQAGLAEFPDCKAARSARHMEELAGVVTAGGRAMLIVVIQMRAGAFDVARDIDPVFDRALRMALEVGVEAYAYTCAVGPEGVAIDTPVPILTPGATLQPARTSG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RNC_RHOBA
Sequence: MDASSSSNPDDGLQAIRLVDASDDEPYADAVAKIERCQEILGYDFRDLDLLRSALTHASGASHRLASNERLEFLGDSVLGLTVCEWLFNEYPEYSEGDLTKIKSAVVSRRSCGKVACKLGLDQCLIVGRGVTRNRSYPKSLVSDVFEAVIAALYIDGGPEIVRDRLKLWLAEEVNLAVDTQGSGNHKSVLQQFAQRELSATPVYKLIRETGPDHRKMFLMGAMVDDRRFAPAWGNNKKDAEQRAAANALAELHNAKVPYDSEQPPA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRP1_YEAST
Sequence: MAGAPAPPPPPPPPALGGSAPKPAKSVMQGRDALLGDIRKGMKLKKAETNDRSAPIVGGGVVSSASGSSGTVSSKGPSMSAPPIPGMGAPQLGDILAGGIPKLKHINNNASTKPSPSASAPPIPGAVPSVAAPPIPNAPLSPAPAVPSIPSSSAPPIPDIPSSAAPPIPIVPSSPAPPLPLSGASAPKVPQNRPHMPSVRPAHRSHQRKSSNISLPSVSAPPLPSASLPTHVSNPPQAPPPPPTPTIGLDSKNIKPTDNAVSPPSSEVPAGGLPFLAEINARRSERGAVEGVSSTKIQTENHKSPSQPPLPSSAPPIPTSHAPPLPPTAPPPPSLPNVTSAPKKATSAPAPPPPPLPAAMSSASTNSVKATPVPPTLAPPLPNTTSVPPNKASSMPAPPPPPPPPPGAFSTSSALSASSIPLAPLPPPPPPSVATSVPSAPPPPPTLTTNKPSASSKQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDRFVVGGDTGYTTQDKQEDVIGSSKDDNVRPSPISPSINPPKQSSQNGMSFLDEIESKLHKQTSSNAFNAPPPHTDAMAPPLPPSAPPPPITSLPTPTASGDDHTNDKSETVLGMKKAKAPALPGHVPPPPVPPVLSDDSKNNVPAASLLHDVLPSSNLEKPPSPPVAAAPPLPTFSAPSLPQQSVSTSIPSPPPVAPTLSVRTETESISKNPTKSPPPPPSPSTMDTGTSNSPSKNLKQRLFSTGGSTLQHKHNTHTNQPDVDVGRYTIGGSNSIVGAKSGNERIVIDDSRFKWTNVSQMPKPRPFQNKTKLYPSGKGSSVPLDLTLFT
What is the function of this protein?
Involved in cytoskeletal organization and cellular growth.  May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins (e. g.  profilin) or proteins possessing SH3 domains.
What are the official names of this protein?
Verprolin.
What is the protein family that this protein belongs to?
Belongs to the verprolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL13_PSYCK
Sequence: MKTLSAKPAEVTHDWYVVDADGKTLGRLATQIATRLRGKHKPSFTPHVDTGDFIVVINADKITVTGKKAQDKKYYRHSGYPGGIKETNFSKLLAHKPEDVLHKAVKGMLPKGPLGYAMIKKLKLYAGTEHPHEAQQPKALDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CARA_ACEWO
Sequence: MAKFISAKEAAKLIPDGSTVGVAGMGLAGWPEEVAVAIADNFKETGHPCNLTMKQGSAMGDWRERGMTRLGLEGLVTKWSAAHIGSAFAMNDLVRAEKMACHCLPQGVIVNLWREIAAKRPGLITKVGLGTFVDPRLEGGKMNKVTTEDLVELIEFNGEEYLFYKSFKLDVAMLRGTTADENGNITFENEGPINEGLAVAQAAKNSGGIVIVQVEYQALKNTLKPKDVKIPGALVDYVVVATDKNACWQTEGVYYEPAFAGNLRKPLSAIPILPLTERKVMARRAAMELSKGDLVNLGVGIPSDVASIVSEAGYIEEITMTTEIGGFGGIPASLPNFGSSYNAEANIDHGSMFDLYDGGGIDVAVLGLAQADEAGNINVSKFTIPGLGDRLTGPGGFINITQSTQKVVFAGSFNAKCEVEISDGKLIIKKEGRGKKLLKEVEQVTFSGKYAAENGQEILYVTERCVFKLINGKMTVIEIAPGIDLQKDILDQMDFTPAISADLKEMDSGLFSEKWDGLDTIMGK
What is the function of this protein?
Involved in caffeate respiration, which consists in the reduction of the C-C double bond of caffeate.  CarA catalyzes an energy-saving CoA loop for caffeate activation in the steady state of caffeate respiration.  It catalyzes the formation of caffeyl-CoA from caffeate with hydrocaffeyl-CoA as the CoA donor via a ping-pong mechanism.  In addition to caffeate, the enzyme can utilize 4-coumarate or ferulate as CoA acceptor.  Neither acetyl-CoA nor butyryl-CoA served as the CoA donor.
What are the official names of this protein?
Caffeate CoA-transferase, Hydrocaffeyl-CoA:caffeate CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
Protein: PUR9_YERPP
Sequence: MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DAPF_HYDS0
Sequence: MLITKYQGSGNDFIIIDNRDNFVYKEIEKLGLSINEFVRKLCEQHTSVGADGVILIEKARNTKNHFSWAFFNADGSAAEMCGNGSRCAARFAYEKDIAPKDIVFETIAGEIEAHIMDSKRVKVQLTPYHSHQKNIEIKTEYGTFKGHFVNTGVPHFVIFVDEDELDNLDVEKVGRAIRYHEYFAPKGTNVNFVAKTKNGSFRIRTYERGVEGETLACGTGSAACGINAYLLGLSASNIVDIITKSGELLKITIENDKVFLEGPTTKVFEGMLSYEIF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_LISW6
Sequence: MANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLEASVYSNMTAWDKFQVARHPERPTTLDYISLLFEDFMELHGDRAFGDDAAIVGGVATFNGIPVTVIGHQRGKDTKDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTKGAYPGRAAEERGQSEAIARNLYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDAGQAKKAAESMRITADDLFELGITDGIIPEVKGGAHRDLTAQAAEINKTITKSLHALMAFSEEQLMNQRYEKFKKIGVYEIL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_RICBR
Sequence: MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANISGPIPLPRKIQRFTVNRSPHVHIKSREQYEIRTQKRLLVIDDPNPVVVDALSKVDLAAGVDVVIELESGE
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y993_HELMI
Sequence: MRGGTVLLILILLLGVIARSPMTALAAASILALSYLGWGGLLEWIEQNGVDTGLIMLTLAMLAPFATGKVGLREVLLSFASLPGIIAVIGGVLATNLNKRGIDLLSGEPQIIVGMIVGSLLGIVLFGGIPVGPLMAGGLTALILQIYGWLSK
What are the official names of this protein?
UPF0756 membrane protein Helmi_09930.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.