PharMolix/UniProtQA huggingface dataset:
Protein: SYT_LEPBJ
Sequence: MYQLTLPDKSVKKVALGSTYRDFIEKELPFLKNKALAVRLNGKDIQDLSRVVETDANIEVLTYTEKAGWETFQHSAAHLLGMAVQNLYKNANLTVGPVIENGPGFFYYDIDFQGTIITPEDFPKIEAEMERIVKADYTVWRKVVPKKEAIETFQKLGEKYKIEIIGGILSEEVSIYGMGEWFDLCRGPHVSNSGILKSFKLTAISGAYWKADKDNAMLTRIYGVAFPSKKELDQYLFQIEEAKKRDHRKIGKELDLFSFQKEGPGFPFWHPKGTILWNSLADYLRAECNKRGYQEIKTPAVLSSELWKKSGHWDNFHENMYFTDIDEEDYALKPMNCPGCSLIYKHHLHSYRELPLRFAEFGSVHRHELHGVLHGLFRVRAFTQDDSHIYAPLEHLESEVTDIIDFTFTVYKKFGFSEFKTFIATRPEKSQGRDEDWEFATNTLKQSLEKKGIPYGIKEGEGAFYGPKIEFNIKDSIGRLWQCGTIQVDFSMPERFELDYTDSDGQKKRPVMIHRAIYGSLERFIGILIEHYEGKFPLWISPNQIRILTITEKVAEYAKDVYCELVDAGFRVELDTRNEKIGAKIRDSILKKANYLLILGEKEMESGTLAVRKRGQEDTKTLTRSGFISNLQDEIKSAG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_BUCAI
Sequence: MPDISLKVLSNEIKISIQELIKELSIIGITKTEDNYINVLEKNILLKHLESKKKYSLDTLVLQRKTRSTLRISTVGGKNKSVQVEVRKKRAYVKNNKFENESFLNEKKVIKHSMQKTSSLKNKEKKYIKNIEKIELNKSDSRSLNTKKENKLKISNKDEQNKKFNQHRESNSFDLNHKKRIKENKDIRISHKEEKQDYHLTTFLHARQAEDENDREVEIDKRNHGRILKNYRQKKNNKNFHNGRYNKEEIRTFNRNKKNSKQKNKPILLQQVFQKPESIINRDVIISNTITVSDLANKMAIKSSEVIKNMMNMGIIGTINHVLDQDTAQLIAEEMGHKVIVHRENALEELIMKDRDTGNDVSAIRAPVVTIMGHVDHGKTSLLDYIRSTKTAFYEAGGITQNIGAYHVKTDLGSITFLDTPGHSAFTAMRSRGVQITDIVILVVAADDGVMPQTIEAIQHAKEANVPVIVAINKIDKTDSDIDKVRNDLMKYNILSEEWGGENIFVSVSAKTGKGINKLLNVILLQAEMLELKAVTTGMAEGIVVESFLDKGRGPIATVLVKKGQLKKGDVILCGFEYGRIKSLRDASGNEVFSAGPSIPVEVLGLSKVPFSGDVVTVVRDEKKAREVASYRKEKSREKKLSNQNRINLENMFDDINKNNVSELKIILKSDIQGSLEAISGALLKLSTEEVKIKIIGLGIGGITETDASLALASNAIILGFNVRADTSAKKIINSEHLDLRYYSVIYDLLDEVKAAMTGLLSPEYKENIIGLAEVRNTFKSPKFGLIAGCMVTEGVIKRSNPIHILRNNIVIYEGELESLRRFKEDVNEIRNGLECGIGIKNYNDIRVGDIIEVFEVREMKRIL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_PECAS
Sequence: MEYDYIIIGAGSAGNVLAARLTEESDVSVLLLEAGGPDYRLDFRTQMPAALAFPLQGKRYNWAYETDPEPHMNDRRMECGRGKGLGGSSLINGMCYIRGNAMDFDHWATMSGLEDWSYLDCLPYFRKAETRDVGANDYHGASGPVSVTTPKMGNNELFHAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRASTARGYLDQAKSRKNLTIVTHALTDRILFDGKRAVGVAYFKGESAQTAKARREVLLCAGAIASPQILQRSGVGPKDLLQRLDISVVHDLPGVGENLQDHLEMYLQYACKEPVSLYPALQWFNQPKIGAEWLFNGTGIGASNQFEAGGFIRSRDEFTWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRSLSRGRVQVRSKDAREHPSILFNYMSTEQDWQEFRDAIRITREIMAQPALDKYRGREISPGLAVQTDEELDEFIRTHAETAFHPSCSCKMGEDDMSVVDGQGCVHGMEGLRVVDASIMPQIITGNLNATTIMIAEKIADRIRRRQPLPRSKARYYVAGSTPVRKAPLKPAS
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: GRPE_XANOR
Sequence: MNQDHPEFDSEDLAQNPPETDPLKAEIESLRSEIALVKADALRERADLENQRKRIARDVENARKFANEKLLGELLPVFDSLDAGLTAAGTQPSPLRDGLDMTYKQLLKVAADNGLTLLDPVGQPFNPDQHQAISQGEAEGIAPGHVVQVFQKGYLLNDRLLRPALVVVAKQD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_FRACC
Sequence: MVLDKILRAGEGRILRKLKAIAEQVNLIEDDFTGLSDGELRGMTDEFRQRLADGKETLDDLLPEAFAAVREAARRTLGQRHFDVQIMGGAALHLGNIAEMKTGEGKTLVSTLPTYLNALAGKGVHVITVNDYLAQRDAENMGRVHRFLGLTVGVIHPQMPPPVRRAQYACDITYGTNNEFGFDYLRDNMAWSSEELVQRGHNFAVVDEVDSILIDEARTPLIISGPADHPTRWYTEFARIAPLLERDVDYEVEEGKRTVAITESGVEKVEDQLGIENLYESVNTPLVGYLNNSLKAKELYKRDKDYIVTDGEVLIVDEFTGRVLHGRRYSEGMHQAIEAKEKVEIKQENQTLATITLQNYFRLYDKLSGMTGTAMTEAAEFHQIYSLGVVPIPTNKPMVRLDQPDVVYKTEIAKFDAVVEDIAERHEKGQPVLVGTTSVEKSEYLSKQLRKRGVPHEVLNAKHHEREAAIIAEAGRKGAVTVATNMAGRGTDIMLGGNPEFIAQAELRQRGLSPIETPEDYEAAWQEALEKARQSVKAEHEEVVDAGGLYVLGTERHESRRIDNQLRGRAGRQGDRGESRFYLSLGDDLMRLFNAAAVEGIMDRLNIPEDVPIESKIVTRAIRSAQTQVEGQNFEIRKNVLKYDEVMNKQRTVIYEERRKVLGGADLHEQVRHFVDDTVEGYVRGATADGYPEEWDLDTLWTALGQLYPVGVVAPDVDDRDGLTADHLLEDIQVDAQEAYDRRELDLGDGPDSEPIMRELERRVVLAVLDRKWREHLYEMDYLQEGIGLRAMGQRDPLVEYQREGFDMFQTMMEGIKEESVRLLFNVEVQVAGQEEAATSVGVEPAVSAAPAPPAAAATLPAPAVPTIPDGAGPVADAQPVRPAAARQTPPPPSPVPSAPLPVFVKGLEPRRPTGGLRYTAPSVDGGSGPVTTVDGRSGLGRPAGDGALSAARGEAGTAQPGAGTRPARNAPCPCGSGRKYKRCHGDPARRNTE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SYM_SALNS
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSDENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTTSFDEYWKKDSDAELYHFIGKDIVYFHSLFWPAMLEGSHFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLAAELADPQLYKTFTDAAAVIGEAWESREFGKAIREIMALADIANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPTLSERVEAFLNSELNWDAIEQPLLGHKVNTFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADFPIQETITFDDFAKIDLRVALIENAEFVDGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRQTVMVANLAPRKMRFGVSEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_ECODH
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: AMPA_BACP2
Sequence: MFFSTNELQHKDTLAIGLFQKSQLSGKAKEMDELLEGRITELLKEGDISSKRNQLSKFFPSPETGIKRIYFVGLGKESDYTFEEAKEGFAHLFRKLHQDKKQAVSVLLDTFIGKDLPAQDAAHTLSESCLLATYELQDFKHKTNEPDRFIEFVYAMTDHDTTEIQASLKVGEVYGQSVNSARTLVNMPPNMLTSSDLASYAAELAYKYEFEIEILDKEQMEELGMGGILAVNRGSTEPPKLIVLKYQGKEEWTDVIGLVGKGITYDTGGYSLKPRASMIGMKTDMGGSASVLGAMEIIGELRPEQNVIAVIASTDNMISADAMKPDDVIVSLSGKTIEVLNTDAEGRLVLADGVTYAKQHGASVLIDVATLTGGVIVALGNETTGVMTNNDELYAQFKEASEECGEMIWQLPITEKDKKRVRNSKMADLNNSPGRDGHAIMAGAFIGEFAENTPWVHLDIAGTATTEKPSCFGPTGATGVMVRSLATFVERFEGKK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL7_HAEIN
Sequence: MTALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNKRITGELNPDYRKPYVFKNDFSALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTLPLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMGCSNPHPHGQIWANSFLPNEVAREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKTHVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHFYPPLLRSATVRKFMVGYEMLGENQRDLTAEQAAERLRALSEVHYKERTK
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: IBAG_SHIFL
Sequence: MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVKKQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF
What is the function of this protein?
Involved in cell resistance against acid stress.
What are the official names of this protein?
Acid stress protein IbaG.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: NAS35_CAEEL
Sequence: MHKIFIIFGLLSLCAAHSLRDLSNKDEEDPPSSAPGVRKRRMMSEEDQKTVDYYMDKLNKLADEKHPEEIERHKNPELVAWDRKRDSVLNPEEQGKFFQGDIVLYPEQAKALYEQALTEGKTRVKRKFIGSNLRRWDASRPIIYAFDGSHTQREQRIIELALEHWHNITCLNFQRNDQANSGNRIVFTDVDGCASNVGRHPLGEEQLVSLAPECIRLGVIAHEVAHALGFWHEQSRPDRDQYVTVRWENIDKDSKGQFLKEDPDDVDNAGVPYDYGSIMHYRSKAFSKFDDLYTISTYVTDYQKTIGQRDQLSFNDIRLMNKIYCSAVCPSKLPCQRGGYTDPRRCDRCRCPDGFTGQYCEQVMPGYGATCGGKISLTRSTTRISSPGYPREFKEGQECSWLLVAPPGHIVEFQFIGEFEMYCKIRHSLCMDYVEVRNSTDFANTGMRYCCYGTPPTRIRSATTDMVVLFRSFYRGGKGFEARARAVPEAGNWNSWSPWTACSATCGACGSRMRTRTCPPGNACSGEPVETQICNTQACTGMCAQKREEEGQCGGFLSLLRGVRCRQEKTVMAPCENACCPGFTLQRGRCVR
What is the function of this protein?
Metalloprotease which cleaves the carboxyl terminus of procollagens, such as sqt-3, to mature collagens (By similarity).  Involved in cuticular collagen maturation (PubMed:15579684).
What are the official names of this protein?
Zinc metalloproteinase dpy-31, Nematode astacin 35, Procollagen C-proteinase, Tollish protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: HISX_SALTY
Sequence: MSFNTLIDWNSCSPEQQRALLTRPAISASDSITRTVSDILDNVKTRGDDALREYSAKFDKTEVTALRVTPEEIAAAGARLSDELKQAMTAAVKNIETFHSAQTLPPVDVETQPGVRCQQVTRPVSSVGLYIPGGSAPLFSTVLMLATPARIAGCQKVVLCSPPPIADEILYAAQLCGVQEIFNVGGAQAIAALAFGSESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDADIARKVAEAVERQLAELPRADTARQALSASRLIVTKDLAQCVAISNQYGPEHLIIQTRNARDLVDAITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKAGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: KUP_CHLTE
Sequence: MSLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTFIMKADNEGEGGILALTALIISHSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAVEGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFFGPIILLWFTSIGLCGLVEIVKYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSLLVLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIFSLTQQGIQLGYIPRLTVQHTSASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGVAVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDLSFFGASVSKLFHGAWFPLVIGFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPMALLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIRQVLALANQQGMHFRTDAISYFINREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLPSGQVIEIGVQVQI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT_RICBR
Sequence: MTFPNINPIIFSVGPLAVSWYSLSYVVGILFGWFYASKIIEKFPTQITKKNLEEFVTYAIIGIIVGGRLGYILLYNPYKYFSNPIEILKTYEGGMSFHGGAIGVIIAAYIFCKRHKLNFLSLTDIIAPVVPIGLFFGRIANFINGELYGRVTNSSIGVIFPDSDLNLRHPSQLYEAFFEGLVLFCILAYAVFKRNTIKKQGLNSGLFLMFYSLFRIIIEIFREPDVQIGFIFDSLTMGQILSMPLLLLGIYLIIKTECRSITK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENV_MLVFF
Sequence: MACSTLSKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALSGPPHWGLEYQAPYSSPPGPPCCSGSSGNVAGCARDCNEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRVYWKPSSSWDYITVDNNLTSNQAVQVCKDNKWCNPLAIRFTNAGKQVTSWTTGHYWGLRLYVSGQDPGLTFGIRLSYQNLGPRIPIGPNPVLADQLSFPLPNPLPKPAKSPPASSSTPTLISPSPTPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVASQHKLTLSEVTGRGLCIGTVPKTHQALCNTTLKAGKGSYYLVAPTGTMWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSHRHKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLHAAVQDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLSQRQKLFESSQGWFEGWFNRSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPLEYEPQ
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: RL27_STRPS
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: APAH_ALISL
Sequence: MATYFVGDIQGCLDELLLLLDQVSFDKEKDQLWLTGDLVARGPKSLETLRFVKSLDKAAVTILGNHDLHLLAVSQGISRIKEKDKTASIFTAPDSEELLTWLRHQPLLATHAQHNIVMTHAGISPQWNIETATECAREIESVLVSDKWVWLLENMYENQPDLWQSDLTGINRYRYIINAFTRMRFCYPDGRLDMECKQPPQELSSDDKEKLIPWFDLKSRCPLSHTVIFGHWAALMGYENNGVIALDTGCVWGEYMTMYRVDDGQYFTQKAIS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: NAT10_DROME
Sequence: MVKKKIDNRIRVMIENGVKLGHRTMFIVIGDKARDQVPILYDILTKSTVKARPTVLWCYKNKDEAISNHGKKRAKKIAVGKVDVNEADLFDSFRVATTIHGRYYSETHAVLGRTYGVCVLQDFEALTPNLLARTVETVEGGGLIILLLKTLQSLKQLYTMSMDVHKRFRTEAHQTVTCRFNERLILSLADCKRCLVVNDDLTVLPLSSKTINVEPVNPAGAGRSPNEASLKELKESLLTVQPAGALVNLCKTYDQANAVAQFIEALVDKQLKPPMSLTAARGRGKSAALGLSIAAAVAFGYVNIYVTSPHPENLITLFEFVLKGFDALEYQEHADYTIIRSTNADYKKAIIRINITRSSRQTIQYIAPSDTHLLNAADLLLIDEAAAIPLPLVKKMIGPYLVFMASTINGYEGTGRSLSLKLISQLQKDNNARPPLKLEESIRYQENDDIEKWLINLLCLDASTVPSISSGCPTPDACELYYVDRDALFSYHKAAEAFLHRLVSIYVSSHYKNTPNDLQMMSDAPAHHLFCLLGPVQRMDALPEILVVIQVALEGQISAQSISDSLGRGKKAAGDLIPWNVAEQYGDRDFPKLCGVRIVRVATHPNYQRMGYGKRAIQLLKDYYARKHTNLEDGPVASKDAGKGIEEVEEEELSLLKEQIRPRSRIPTLLQRLHERVPEHVDYIGTSYGLTTELLKFWKNAGFVPVYLSQKSNELTAEHSCIMLHTPNATPWLGLYYQDFRRRVLKLMGKTFREFETKLCLALLKNKSVDTEGSALKVLDKPMLDVYFLPHDLQRLESYARQQSEFRLIIDLLTDIAQLYFQGRIDGLQLDLVQQGILLALGVQGKTVDALGLELNMPGNQLLAKFFDAMKRCNQCFRSVLEEHIEGGMLREADLSKGEELQPLTLSLDKELDQTAQKLSKQQRKELKRLKAEQLDEFQIKGTEEDWSKALETNGTGGGSGLLSVKSGVKRLDGPIETREDGDLAAPLSKKKKKNNPKQRRSQGKSLI
What is the function of this protein?
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs.  Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA.  Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis.  Catalyzes the formation of ac4C in serine and leucine tRNAs.  Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (Probable).  Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (PubMed:11493925).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
RNA cytidine acetyltransferase, 18S rRNA cytosine acetyltransferase, Polycomb protein l(1)G0020, p110.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL2_METPE
Sequence: MGHRIKTQNRGRGGPTYRAPSHQYKAELKHLGNDKVTVRGVIIDIEHDPARHTPIALVRLEGEGKKVYLLVTEGLGVGDQVAWGPEAEVKNGNTLPISKIPTGSYICNIEARPGDGGKFVRASGVQAIIIDKTVDRVGVKMPSGKMKWFSSRCLATVGVVAGGGRGEKPFVKAGKKFHKVKSQATYWPRVRGVAMNVIDHPFGGGGHQHTGRPKTVSRGTSPGRKVGSVAARRTGRRKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y3003_CLOBH
Sequence: MDNNFKIKDLPKNERPQERLIRYGAEVLSNSELLAVILRTGTKNQNIMMLASSLIKETGGLDQLFNQSIEELTKIKGIGVTKAVQILALSELSKRFKTYKSGNEYKISTPLDVSNLVMEDMKYLKQEKLKILILNTKNIVTYIRDVFIGTLNSSIVHPREIFCEAIKKNGASIIICHNHPSGDPTPSKEDINITLRLKECGKLIGIDLLDHIIIGENKYVSMKEKGTI
What are the official names of this protein?
UPF0758 protein CBO3003/CLC_2900.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SDR1_PAPSO
Sequence: MHGQKNISERYQKFKEMEGTGKIVCVTGGAGYLASWLIMRLLERGYSVRTTVRSDPKFREDVSHLKALPEATEKLQIFEADLENPESFDDAINGCVGVFLVAQGMNFAEEYTLEKIIKTCVEGTLRILQSCLKSKTVKKVVYTSSADAAMMISNLKAVKEIDETIWSEVDNFISKPEQVIPGLPSYVVSKVLTERACLKFSEEHGLDVVTILPPLVVGPFITPHPPPSVSIALSIISGDVSMMLGVRLENAVHIDDVALAHIFVFECEKAKGRHICSSVDFPMHDLPKFISENYPEFNVPTDLLKDIEEQEPVHLSSDKLLSMGFQFKYDFAEIFGDAIRCAKEKGFL
What is the function of this protein?
Oxidoreductase that catalyzes the last step in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:27378283, PubMed:29610307).  Converts narcotine hemiacetal to noscapine (PubMed:27378283).
What are the official names of this protein?
Noscapine synthase SDR1, Short-chain dehydrogenase/reductase 1, PsSDR1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: NANM_HAEIN
Sequence: MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDLKDPSAQWKEIATFPGGERNQPVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTWMKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQDTVAAGEDKAKKDEIAAAYFDQRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNELVVVNGEIKPGLRTAETHQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEGKLHAHKGLSKAWHNEVYTLNNGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALTSVKAISYDGKKLTIE
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity).
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS11_METMA
Sequence: MADMKWAVAHIKSSFNNTIITVTDITGAETIAKSSGGMVVKAARDESSPYTAMQMAGQLADQLRDKGINGIHIRVRAPGGNKQRSPGPGAQAAIRAFARAGIRIGRIEDVTPVPHDGTRPKGGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.