PharMolix/UniProtQA huggingface dataset:
Protein: RT106_ASHGO
Sequence: MPEFLERLPHAVKQKVLQISNNDAKILGVFEQVFQCGQENQDARRKAVKTGVSERLEDSELIFELRDVSFLSPIRKKLNLAITIGSDGKPALLFNKDRVPEMAIPNLQESVKFAAFLPFPEKKNLLYLFIVYRTASDEAPDPVLLTMNKEGVLKQFKDKGLIPVDSSNFGECVDYMRKQAILTGFRIGDPFSNSQGPPAFHVECHRGTKEGTLYFLPDHIIFGFKKPILVFESNEIESITYSSITRLTFNVTLITKNQEKYEFSMIDQSEFANIDEYVKRNQVKDKSMSDELKAKPMVKAHQVGEQSALKEAQQQLRENRPTGGVPIDSDDEEADGNFESESELSDGSGSDSEADSDEDADDTDDSDGTNDTHDVLQHEEIQIAAADAEDEVLPDFDQAEAGIDIVIEEDDEEEGSGVEYD
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone RTT106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LIPA_AERPE
Sequence: MEAAKPRLRVRINDSYVKVARLVAGLGVATVCEGALCPNIFTCWGEGTATFMIMGDTCTRGCRFCYVKKGVPEPLDPLEPYKVALAVDALGLDYVTLTSVDRDDLPDGGASHFAATVRAIKRLRPDTIVEALIPDFQGVEEHVRLVAASGLEVLAHNIETVERLTPLVRDRRAGYRQSLRVLEIAKEEGVVTKSSILLGLGEDKSEVIEAMRDLRSVGVDILVLSQYYRPSRKQLPVAKRYSLSEFRELAEKGLRMGFAYVVAHPLARTSFKAKEAYLAAVRRVEAEGGGRRA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_PROMM
Sequence: MAVNPQGVAAVLADLKGRDFLSCADFTAEQTVALLELSRQLKSGDRRIDLGNRVLGLIFTKASTRTRVSFQVAMARLGGQTVDLNPQVTQLGRGEPLEDTARVLSRFCDVMAVRTFAQQELLDYAHWASIPVLNALTDLEHPCQAMADFLTIQEALGSLTGQTLAYVGDGNNVSHSLMLCGALLGVNVRIGCPQGFEPLPEVIDQARNLAVADARIEVMTDPVDAVRGAQALYTDVWASMGQEQEQSQREEAFRGFCLNEDLLAHADPNAIVLHCLPAHRGEEISSGVMEGEASRIFDQAENRLHVQQALLAAVLGGL
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB8_PONAB
Sequence: MAVARAGVLGVQWLQRASWNVMPLGARTASHMTKDMFPGPYPRTPEERAAAAKKYNMRVEDYEPYPDDGMGYGDYPKLPDRSQHERDPWYSWDQPDLRLNWGEPMHWHLDMFNRNRVDTSPILVSWNVMCMQLFGFLAFMIFMCWVGEVYPVYQPVGPKQYPYNNLYLERGGDPSKEPERVVHYEI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Complex I-ASHI, CI-ASHI, NADH-ubiquinone oxidoreductase ASHI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: METN2_STAAS
Sequence: MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: THIE_PSEP1
Sequence: MKLRGLYAITDSQLLAGRFLSHVEAALEGGVCLLQYRDKSDDAARRLREAEGLMKLCERYGTQLLINDDAELAARLGVGVHLGQTDGPLTPARALLGRQAIIGSTCHASLELAAQAASEGASYVAFGRFFNSVTKPGAPAANVGLLEQARAQVKLPIAVIGGITLDNAAPLVAHGADLLAVIHGLFGADSAQEVTRRARAFNALFAS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RS20_BRADU
Sequence: MANTTSAKKATRKIARRTAVNKSRRTQMRGAVRNVEEAIKTGDRAAAVKALANAEPALMRAAQRNIIHKNNASRKVSRLTAQIAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: LIC4_KLULA
Sequence: MYQSMDLDDIKGHSHIINEDAEFDKTDSDNTFALELQKIIQQETNGGKVQDDVLAEAIATVDVDLPYLSNVSSPGLVYGTNKQSEHPQSHGGKDSDLTVEHILGDLQSGTEDDKEFTDRLNRLLCAPDSLKRGFSGDMEIDIPSNKKRKSVYETLSPPESMSPLSDKNDAQQNRDLNTHKDFSAMKRKINSQRMLKQVPLPPKLTNEFTMTQVAEMKKRVINTHKLILNFNFLKDGYARSCEELSKTVVKLKDSEFDRARLVKENQDLKRMVLEMSKQLNEKQ
What is the function of this protein?
Involved in cation homeostasis and in the regulation of the cation stress signaling cascades.
What are the official names of this protein?
Protein ATC1/LIC4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: QUEA_METPB
Sequence: MRVDLFDFELPEAAIALRPASPRDASRLLVVRPGETLADRGVRDLPALLNPGDALVFNDTRVIPARLSGIRHRAGGTGQRCEAMLHLREAPDRWRAFARPAKRLAPGDRIRFGGEGANQGASEVCVLSGLDATVEERGEGGEILLRFDLAGPALDEAIAGLGALPLPPYIAGKRATDARDTTDYQTVYAREPGAVAAPTAGLHFSDALLDGIDAAGIERIHVTLHVGAGTFLPVKADDTEAHRMHAEIGILDTATAERLNAVRARGNRIVAVGTTALRLLESATDPDGTVRPFSGATDIFITPGYRFRAVDALVTNFHLPRSTLFMLVSAFSGLDTMRAAYAHAIASGYRFYSYGDASLLFPERAP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL17F_HUMAN
Sequence: MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
What is the function of this protein?
Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:21350122).  IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains.  This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation (PubMed:18684971, PubMed:21350122, PubMed:11591732, PubMed:11591768, PubMed:17911633, PubMed:11574464, PubMed:28827714).  IL17A-IL17F is primarily involved in host defense against extracellular bacteria and fungi by inducing neutrophilic inflammation (By similarity).  As signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites (By similarity).  Stimulates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers (By similarity).  IL17F homodimer can signal via IL17RC homodimeric receptor complex, triggering downstream activation of TRAF6 and NF-kappa-B signaling pathway (PubMed:32187518).  Via IL17RC induces transcriptional activation of IL33, a potent cytokine that stimulates group 2 innate lymphoid cells and adaptive T-helper 2 cells involved in pulmonary allergic response to fungi.  Likely via IL17RC, promotes sympathetic innervation of peripheral organs by coordinating the communication between gamma-delta T cells and parenchymal cells.  Stimulates sympathetic innervation of thermogenic adipose tissue by driving TGFB1 expression (By similarity).  Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes (By similarity).
What are the official names of this protein?
Interleukin-17F, IL-17F, Cytokine ML-1.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LOR10_ARATH
Sequence: MAIVSPNFCAPYPIELGIVRKVMTLTDGNFAVTDVNGNLLFKVKEPLFSISDKRILLDAYDTPILTLRENKVSLHDRWLVYRGKSTDQSDLLYTLKRSSMIQIMKPKLDIFLAHNKEMKICDFHVKGSWIDRSCVVYAGKSDAIVAQMHKKHTAQSILIGKSNFSVTVYPNVDFAFIVSLIVILDDINREDSED
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 10.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: RNPA_SALAI
Sequence: MLTAAQRLRRSTDFAAAVRGGRRVGRGVVVVHLNVPGIPPEASAKPARAGVEETLAPARAGFVVSKAVGNAVVRNRVRRRLRHLVRERLTGLPAGSTLVVRALPAAAHGSTQRLGADLDAAIAAARAQRGRRSR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS19_METAC
Sequence: MAKKSSSRLPKRKGEYTYRGKTVSELQELSLEEFAELLPSRERRSLKRGFTDGQKKVLHEFKEGKKIRTHHRDMIILPEMIGKTIEIHNGKGFVSVDLQPEMVGHRFGEFAPTRSRVSHGSAGVGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RPOB_RHOBA
Sequence: MATTTQRRLEPTSIRKFGTGLGQFDLPDLTALQTVSYAAFLQEDAASNARKDHGLESVLREIFPIASYDGNTTLEYLYYELGKPRYTIQECRQLRLTYGRPLRIWLRLNREEPIEEEVYLGDLPIMLGGGEFIINGAERVVVSQLHRSPGVDFVLEQDTTTDRKLPSCRVIPERGSWIEVNVTKKDALTVRIDQSGKFAATMLLRAMDPKYSTDADLLSAFYETGTIKVNGGKDATKIENKIAVDDVVYPSGHERAGEIIVEAGYKITTELSETICNAGVTSVEAMDLPKVPLIFNTLADDNTASHEEALLRIYQRLRPGNPPQLEKARTLFQEKFYDDNRYRLGKVGRFRLNRKLGLGVEETVMTLRPDDMIAAIRYLIDLFDADSGAEIDDIDHLGNRRLRTIDELASEELRKGFLKLRRTVQERMSVKDAQDMTPRSLINPKSVSAAIDFFFGRGELSQVVDQTNPLSQLAHERRLSALGPGGLNRKRAGFEVRDVHISHYGRICPIETPEGTNIGLISSLAIYAGVDDYGFLCTPFRKVIDGKISDETVWLRADEEGESYVAPADTEVKDGALVPGPNMIARFRSDFEIVMPEQVSFMDVAPAQMVGVSAGLIPFLEHDDANRALMGSNMQRQAVPLLVTEPPIVGTGMEREVAKNSAMVVRARRAGKVTYADATRIEIGSDHYPLKKYQGLNERTCQNQKPLITVGDKVEKGQIIADGAATQKGELALGRNVLVGFMSFDGFNYEDAIIISEELVRNDTYTSIHIEDFDVEIRETKLGREEFTRDIPNVSEKALRNLDDTGIVQTGTYVKPGDILVGKVSPKSKTELTPEEKLLHAIFGRAGEDVKNDSLEVPSGIEGIVIDTQKFSRRMSLGEDERKAFERELKQHETEGNEEIASTFESLIRDMEEASGVKLKDSTGTPLADGQDPKFVAERATSFRLELVLEQIEDEEKRKAAEKVHQTQWQNVEQAIDERDRKLNSMKRGDELRSGVLQMVKIYIATKRTISVGDKMAGRHGNKGVIAKILPIEDMPFLPDGTPIQIMLNPLGVPSRMNVGQILETHLGWAGAKLGFQALTPIFDGASESEINDCLAEAGLPAHGKIRLTDGRTGEPMEQETTVGYIYMLKLHHLVDDKVHARSTGPYSLITQQPLGGKARFGGQRFGEMEVWALEAYGAAYILQELLTVKSDDVEGRTKIYESMVKGENTLEAGTPASFDVLTNEIRGLALNMQLEKRPI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TDXH_METJA
Sequence: MPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQKRYDEFRKLNTELIGLSIDQVFSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPYKGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVKALQVSDEKGVAMPANWPENDLIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRAM1_XENTR
Sequence: MPCWCLHGAAFLPSILVIWSSAGFLFSYIISVLIGHVPPFVPYISDTGTSPPESGVFGFMISLSAMLGAATMYTRYKILEKQNHSTDFLPYYFNKTSLAIGLLGCIGMGIVATFQEMAVPAVHDAGALITFICGVLYILLQSYISYKSCPAWNTRVTCHIRMAISVIAFIAVVPMSVFSVLSGRKRLDWKPSDEGYHYHLTSAICEWIVAFGFNMYFLTFIRDFQGVSIQISTEIHEDF
What is the function of this protein?
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: TRHO_BUCAT
Sequence: MSILHNIVSKKELKRRMFFETEPRLTLSFYKYFFIKNTQEYRDRLYKNFYKYNVLGRIYVASEGINAQISVPKKYYSILKKFLYNFDIELNNLRINKSLDNEKSFWVLCVKIKKKIVQDGIKEHFFNPNNVGIYIQSEQVNSMLNDKKTIFIDMRNSYEYAIGHFENAIEIKSITFREQLKKVIQLMAYAKNKKIVMYCTGGIRCEKATSWMLFNGFKHVYHLEGGIIGYVHDARKNGLPVLFKGKSFVFDNRMSEKISDEVISYCKQCGKSSDVYINCKYSSCHLLFIQCENCSVKFHSCCSLECMKKYNFYMLNNDLKKISY
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: TRUA_ACIBC
Sequence: MQRYAVGIEFSGIQYRGWQTQQPGVASVQETIELVLSKIADEPITLHGAGRTDAGVHATNMVAHFDTNAIRPERGWIMGANSQLPKDISIQWIKQMDEEFHARFKATARRYRYVVYNAPHRPALLHKQVTHIYQKLDVQKMIKAASKFEGTHNFETFRAAACQSNQPVRHVKHCRLFEHGRYLVLDIQADGFLHHMVRNIMGCLLEIGQGMYEIDHIDAMFAAEDRKAAGITAPPDGLYFIQCYYPEQFDLPQPPLGPHWLNLPE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LIGB_SALTY
Sequence: MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEIARLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLVDRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTNKYTLAVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQHWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASATCQEQFISRLIWLGSRSALGLDGMGEASWRALHQTHRFEHIFSWLTLTSAQIANTPGFAKGKSEQIWRQFNLARRQPFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWRQLPATGERRAGRVIDWRNNLQIKALSRWLAAQHIPGFGS
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: PTLA_STAAC
Sequence: MNREEVQLLGFEIVAFAGDARSKFLEALTAAQAGDFAKADALIEEGNNCIAEAHRAQTSLLAKEAQGDDIAYSVTMMHGQDHLMTTILLKDLMKHLLEFYKRG
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA3_YEAST
Sequence: MASETPRVDPTEISNVNAPVFRIIAQIKSQPTESQLILQSPTISSKNGSEVEMITLNNIRVSMNKTFEIDSWYEFVCRNNDDGELGFLILDAVLCKFKENEDLSLNGVVALQRLCKKYPEIY
What is the function of this protein?
As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair.  Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity).  Stimulates the activity of a cognate strand exchange protein (SEP1).
What are the official names of this protein?
Replication factor A protein 3, RF-A, Replication protein A 13 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 3 family.
Protein: AGS_AGRRH
Sequence: MRVNDSPSDEVYQTRLQGAQTAMKRAGIDVLALSGPDFHNYFAGLWGLPVGRPVWFVLQQYGKPAFVAPRSEAREISARCKTPVAVEWVEWEGPIAAPMTNQDALAQYTRGIAPNPGLIGLDFNCTSGANVELVRQALGAEHIKDVTPMLQELWACKDAAGIAAIRQSCDIVREQFLACRNAIAPGIPEWKVTLASVTAAIERNGELLAEDEELPRFWPHQLNMVGSGADRTARCHPSGGGRIMQDGAIAQICLCGQTFRGHAACFDRPVPIGSKPLPANLRKVIDVAREAQSAALAALRPGVTAGEIHAAAVAVIKRSGWEAPFLHRTGRGIGYSDWDGIELKAGSQTVLEVGNVLSIEPGVYVQGIGGARFGDTVLVSETGYEVLTPFDLGRNI
What are the official names of this protein?
Agropine synthesis cyclase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: FADJ_YERPN
Sequence: MGASATNSVTHPAFTLNVRPDNIGIITIDVVGDKVNTLKAEFADQIATILQQAHALPKLQGLVIVSGKPDSFIAGADITMIAACRTAHDARVLAQKGQSILAQIAAFPVPVVAAIHGACLGGGLELALACHSRICSLDDKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSKALDMILTGKQIRPRQALKMGLVDDVVPRDILLDVAIQRAKAGWLNRRALPWQERLLSGPLGKALLFRIVRKKTLAKTRGHYPAAERIIDVVRKGLDQGGPSGYEAEARAFGELAMSPQSAALRSLFFATTSLKKETGSAATARAIHRVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMMLISGSTDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVVADRAGFYVNRILAPYINEAARCLLDGEPIESVDNALVDFGFPVGPMMLLDEVGIDVATKIMPILVEQLGPRFAAPPSFDVILKDGRKGRKNGRGFYLYSNPTKNSSPTKNGNSPAKRNSFKWRKNKVKPVDASIYTLLGVTPKAHLGAGVITQRCTMLMLNEAVRCLDESIIRNPRDGDIGAVFGIGFPPFLGGPFRYLDSLGADKVVQALRLLVQQYGERFEPCQRLVTMAEQQQQFYPVDANIDEVTDVAS
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_PECAS
Sequence: MIISKFGLGQQIRHKLLGFPGVIIDIDPEYSLETPTWEEISGNDTPRSEPWYHVVMEDNEGQPMHTYLAEAHLMKEELSEHDHPSLNELAEVIQRRAPQLRH
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPA3_DROPS
Sequence: MSSSKMNGRSIRINRVPATIFAILLTIVLVYFLNFHQEERPAIYGKLRSDNPNRVNLRKMLIAAIQASQRGGLEVLDVARSRQLKVRSKGQTDEGVNDPFTDADGRSHCVMKQGLQRIFPRVRIFSEEDKEHCKESHSYDLDPTVLHETAQVPDVSVNAQDVTVWVDPLDATKEFTEELYEYVTTMVCVAVAGRPVIGVIHSPFNGQTAWAWVGNSMSEYLAGLHPPHGQENELPIITVSRSHTAGAKDLARGIFGEQVNLLTAAGAGYKVLQVVANNATAYLHTSKIKKWDICAGDAILHALGGTMTTLNDQLIRYGPDESPVNTEGLLATLEKHDKYMDQLVKYRTAHNGQLA
What are the official names of this protein?
Putative inositol monophosphatase 3, IMP 3, IMPase 3, Inositol-1(or 4)-monophosphatase 3, Myo-inositol monophosphatase A3.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYB_PASSE
Sequence: MAMNIRKTHPLIKIVNNSLIDLPTPSNISIWWNFGSLLGLCLIIQILTGLFLAMHYTADISSAFSSVAHICRDVNYGWLIRNTHANGASMFFICVYLHIARGLYYGSYLNKETWNIGVIILLLLMATAFVGYVLPWGQMSFWGATVITNLLSALPYIGDMLVQWIWGGFSVDSATLTRFFTFHFLLPFVIVALTMVHLLFLHEAGSNNPTGLISNMDKIPFHPYYSYKDLLGFFILLFFLTFLALFTPNLLTDAENFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILLLVPILHTSKQRSLTFRPISQLLFWLLVANTIILTWIGGQPVEQPFITIGQIASITYFSFFLILFPIAGWWENKMLNL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HUTH_YERE8
Sequence: MTLRPGQMTLADLRHIYQHPVKITLDESAYAPIQQSVDCVQKILAEKRTAYGINTGFGLLASTRIATEDLENLQRSIVLSHAAGVGEPNDDAIVRLIMVLKINSLARGFSGIRLEVIQALITLVNAQVYPHIPLKGSVGASGDLAPLAHMSLLLLGEGKARYQGEWLDARAALAKAGLQPLTLAAKEGLALLNGTQVSTAYALRGLFEAEDLYAAASVFGSLTVEAALGSRSPFDARIHAVRGQRGQIDAARTYRHLLGERSEVSESHRNCDKVQDPYSLRCQPQVMGACLTQMRQAAEVLAIESNAVSDNPLVFADQGDVLSGGNFHAEPVAMAADNLALALAEIGSLAERRISLLMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALTSENKGLAFPSSVDSIPTSANQEDHVSMAPRAGKRLWEMAENVRGILAVEWLAACQGLDLRKGLKTSDALEPARLLLRKHVAYYEKDRFFAPDIEAASQLIALRHMNELMPAHLLPSL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.