PharMolix/UniProtQA huggingface dataset:
Protein: METK_MYCBP
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVQLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_HALH5
Sequence: MKIIEAKHFDDMSLKAAQFMIEKIQRDPTITLGLATGGTPQKMYELLINDHRTNGTSYHQVTTFNLDEYIGLDRHDPNSYYTYMHKALFDHIDIRDEQAFLPNGTASNFNAECERYEALIQQRGGIDLQVLGIGANGHIGFNEPGTSFESSTHIVKLTDSTREANARYFNDLSEVPTEAITMGIQSIMNAKEILLLASGKKKADALYQLIHGKVDESFPASVLQRHEQVTIIADREALQKVAVSSN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: PUS10_THEAM
Sequence: MGGSSISTPLDFNKIVEDVEKTLSKYPLCDHCLGRFFAKYGLGLSNRERGSSLKTMLGFKLYDDYSSKRIGRDSLLALAENAGEPLTRMVEKLFAENVNPKTCFICGGRISDEWLDSVAEAVYEKLKEASVTRFVVGVKLGRNLREKELQLVTETGFTRAESLKNEIKREVGKKVMAKYGLVPDFEKPEATAIVKLDENFNYRVELVITPVLLKGVYNKRGRNISHVPWLAKQGGRKYPLSIQEYLESRLADPFKAKKVKIHAAGREDVDARTLGPGRPLVIEIVEPLVRSYDIEDVNKLIRSDLVEVRVHKPASRRDIELLKQTSREKRKVYRLLVVSSTPISEAQLNELEAYFNDIAIQQRTPIRILTRKKDVLRVRKVYEVRTKPVSSTSFEALVYCDGGLYVKELVHCDQGRTNPCFASILNTELKPVELDVLYIEH
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: PSBZ_OENEH
Sequence: MTIAFQLAVFALIATSSLLLISVPVVFASPEGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: PSTB1_STRPD
Sequence: MMTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSIYENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIARVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTGFFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RF1_DESPS
Sequence: MLFDKFDDLDNRIEHLEGKLSDPEIVNDQKEFQKVVREHAHLSKLNTVYKEYKTACQDVEDNKAILHDDGEDPDLKELAKAELEELNVRIVELDKAIKIILLPKDPNDEKNTFLEIRAGAGGDEAALFVADLFRMYTRFAETMGWKVEVMSSNPLGIGGFKEIIALISGEQVFSKLKYESGVHRVQRVPETETQGRIHTSAVTVAILPEAEEVELHIDMNELKFDVFRSSGPGGQSVNTTDSAVRITHLPTGLVVICQDEKSQHKNKVKALTVLRARLLDKLESEHNAKISEARRSQVGTGDRSERIRTYNFPQGRVTDHRINLTLYKLETIMGGSLDEVIYPLITHDQAEKLKDLE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STRA5
Sequence: MSKETLILLYGGRSAEREVSVLSAESVMRAINYDKFFVKTYFITQVGQFIKTQEFDEMPSSDEKLMTNQTVDLDKMVRPSDIYDDNAIVFPVLHGPMGEDGSIQGFLEVLRMPYVGTNILSSSVAMDKITTKQVLATVGVPQVAYQTYFEGDDLEHAIKLSLETLSFPIFVKPANMGSSVGISKATDESSLRSAIDLALKYDSRILIEQGVTAREIEVGILGNNDVKTTFPGEVVKDVDFYDYDAKYIDNKITMDIPAKVDEATMEAMRQYASKAFKAIGACGLSRCDFFLTKDGQIFLNELNTMPGFTQWSMYPLLWENMGLTYSDLIEKLVMLAKEMFEKRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_BIFBU
Sequence: MATTTGAKRGIWPMIRRIAASDRISGLIMLGFALAGLVLANLPLTAHAFEAVAETHVFIPHTNLDLPIGHWAQDGLLTIFFLTVGLELKQELTTGSLANPKAAAVPMLCAVGGMITPPILFLATTALFSQFGPGEPGSLILATTGSSIPFAEMSHGWAVPTATDIAFSLAVLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSVNAWYWFIGIAVCAVVWAHLVRLKKVPWIAVGVVGILAWIMMFEAGIHPTLAGVLVGLLTPARVMHGEYSPRAERYADKLKPFSALLALPIFALFATGVHFESMSPLLLLSPLVIALIVALVVGKPLGIIVTAWLATHVGGLKMAKGLRVRDMIPAAVACGIGFTVSFLIASLAYTNQELSAEARFGVLVASLIAAAISGVLLSRQSKRFEQAAAVAAAEADAESDVNTHSDELAEHSITLADGTESVEIDFRR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURQ_SPHAL
Sequence: MKTAVIVFPGSNCDRDMAVALETVTGKAPAMVWHRETGLPEGTDFIALPGGFSYGDYLRSGAMAARSPILRAVAEAAGRGVPVLGVCNGFQVLTEAGLLPGALMRNAGLNFVCRTVPLKVENSQSLFTAAYGAGEEIAIPVAHHDGNYFADADTLDRIEGEGRVAFRYLDGVNGSARDIAGVLNDAGNVLGMMPHPERAIDRAHGGTDGLRLFEAALGVLA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ID2_RAT
Sequence: MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVTKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQTSRTPLTTLNTDISILSLQASEFPSELMSNDSKVLCG
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.  Inhibits skeletal muscle and cardiac myocyte differentiation.  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.  Restricts the CLOCK and BMAL1 localization to the cytoplasm.  Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism (By similarity).
What are the official names of this protein?
DNA-binding protein inhibitor ID-2, Inhibitor of DNA binding 2, Inhibitor of differentiation 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HDAC7_HUMAN
Sequence: MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVGPQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPLETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSVAPFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGGTLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEPLPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVVDDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRPLSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQRLASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C.  During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity).  May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.  Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).  Serves as a corepressor of RARA, causing its deacetylation and inhibition of RARE DNA element binding (PubMed:28167758).  In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (PubMed:28167758).
What are the official names of this protein?
Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.
Protein: GLMM_PSEA8
Sequence: MSRKYFGTDGIRGRVGEFPITPDFVLKLGWAVGMAFRRQGNCRVLIGKDTRSSGYMFESAFEAGLSASGADTLLLGPMPTPGIAYLTRTFHAEAGVVISASHNPHDDNGIKFFSGQGTKLPDDVELMIEELLDAPMTVVESARLGKVSRINDAAGRYIEFCKSSVPTSTDFNGLKVVLDCANGATYKIAPSVFRELGAEVTVLAASPNGLNINDKCGSTHLDGLQAAVVEHHADLGIAFDGDGDRVMMVDHTGAVVDGDELLFLIARDLQESGRLQGGVVGTLMSNLGLELALQELHIPFVRAKVGDRYVMAELLARNWMLGGENSGHIVCCQNTTTGDAIIAALQVLMALKHRGQTLAEARQGIRKCPQVLINVRFKGESDPLEHPSVKEASVRVTEQMGGRGRVLLRKSGTEPLVRVMVEGDEEASVRAHAEQLAKIVSEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SYN_AZOPC
Sequence: MKMKRARIVDLLSTPDFNRKVCVKGWVRTRRGNKNISFIELNDGSTVHGIQIVVNVVKLGEDSLKSITTGACIAINGLLVKSKGEGQKVEIQADEIEIYGIADPSVYPLQKKWHSLEFLREIAYLRPRTNTFGCILRIRHHLAYAIHKYFNKQGFFYFHTPIITSSDAEGAGSMFQITDLDIANCPKTKDGEVDYTRDFFGCSTNLTVSGQLEGELGALALGGIYTFGPIFRAEKSNTPRHLAEFWMIEPEIAFYDINDNMDLAEDFLKYIISYAMKYCKDDIEFLNNTYNNELIEHLNFVLSNRFVRLAYSEGIRILEQSNEEFEFPIYWGIDLQSEHERYLVEKYFKCPVIMTNYPKDIKSFYMKQNDDGRTVRGMDVLFPRIGEIIGGSERESDHQKLLKRIKELNMSMDNLWWYLDTRRFGTAPHSGFGLGFERLVLFVTGMQNIRDVIPFPRTPKNAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICAD_STAA8
Sequence: MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
What is the function of this protein?
Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Is required for full IcaA N-acetylglucosaminyltransferase activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthesis protein IcaD, PGA synthesis protein IcaD, Poly-beta-1,6-GlcNAc synthesis protein IcaD, Biofilm polysaccharide intercellular adhesin synthesis protein IcaD, Biofilm PIA synthesis protein IcaD, Intercellular adhesion protein D.
What is the protein family that this protein belongs to?
Belongs to the IcaD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIE_RICCK
Sequence: MHQTNFGFKKVDYTEKQRLVNNVFSNVADKYDLMNDLMSFGLHRLWKDEFIRYIPNLNSHILDVASGSGDIALKLAKKARDRGNNVSLTLSDINEEMLRNAKKKAIDLNLFQNLKFTLASAAALPFSDNSFDYYTIAFGIRNVPDINKALKEAYRVLKPMGKFICLEFSKVKEGILKDFYKFYSFNIIPQIGQMIAGNKEAYEYLIESIDLFPSQDKFRIMIKEAGFEEVNYKNLSNGIVAVHSAYKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SERC4_MOUSE
Sequence: MMGAKVVTGRSTTQGLAQQHGGVSNVVETPFNQASCCGPVSWTSGCHSLTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGSSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPRAQLHNSFWSLKLLFLLGLCVVAFCIPDEDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCSWLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRRKQPNSGLLQASIISCYIMYLTFSALSSRPPETITFQGQNHTLCLPGRNKMEPQIPDTSVAVFSAGIMYACVLFACNEASYLAELFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQRSRARSADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAPHSESPPP
What is the function of this protein?
Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids.
What are the official names of this protein?
Serine incorporator 4.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL4_BURPS
Sequence: MELKLLNSNGQEGAVVNASDVVFGRDYNEALIHQVVVAYQANARQGNRAQKDREQVKHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPDENFSHKVNKKMHRAGLCSIFSQLAREGRLSVVEDIVLEAPKTKLLADKFKAMGLDSVLVITDTVDENLYLASRNLPHVAVVEPRYADPLSLIYFKKVLVTKAAVAQIEELLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS13_COXB2
Sequence: MAARIAGVNIPVQKHARIALQAIYGIGNSRALEICKEAKIDPATKVKDLSEAELDALRTEVGKFSVEGDLRRERSMDIKRKMDLGTYEGIRHRRGLPLRGQRTRSNARTRKGKRKPIRS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GUAA_RALSO
Sequence: MPILSLHNMHDKVLILDFGSQVTQLIARRVREAHVYCEIHPNDVSDAFVREFAPKAIILSGSHASTYEDQDLRAPQAVWDLGVPVLGICYGMFAMTVQQGGKVEASAHREFGYAEVRAHGHTRLLDSIEDFRTPEGHGMLKVWMSHGDKVTEMPPGFKLMASTPSCPIAGMADEARGYYAVQFHPEVTHTVQGRALLERFVLEIAGAKPDWIMRDHIEEAVKSIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGQMVLDMFEGRLHAKVVHVDASEQFLGHLTGVTDPEAKRKIIGREFVEVFQAEAKTLTNAKWLAQGTIYPDVIESGGAKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKREYADLLRRADAIFIEELRGTKATAQDAVAGLCTEDQVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVQTTDFMTAHWAHLPYALLGRVSNRIINEVRGINRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y12K_CMVSI
Sequence: MPGLVPPPDHSKSLFVLAIGITVVSALFVLKSHTFPIAGDNIHRFPSGGQYKDGTKQINYCPPTHARYPKYPDYKWLAATAAIVIPLCLYISYHPGNNIRRICPCCNTYHHP
What are the official names of this protein?
Uncharacterized 12.4 kDa protein.
Protein: RL27_FRAT1
Sequence: MAHKKAGGSTRNGRDSNPKYLGVKRYGGEFVKAGTIIIRQRGTKTHPGVNVGCGKDHTLFALKDGTVKFHTGGALNRKFVSIEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS5_NOSP7
Sequence: MATERKSRTKRAKKEETTWQERVIQIRRVSKVVKGGKKLSFRAIVVVGNERGQVGVGVGKASDVIGAVKKGVADGKKHLIDIPITKSNSIPHPIDGVGGGAKVIMRPAAPGTGVIAGGAVRTVLELAGVRNVLAKQLGSNNPLNNARAAVNALSTLRTLSEVAEDRGIPIQNLYI
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ISPH_MALP2
Sequence: MKIIKITPRGFCKGVVDAYATCKKIAKLYPNHEKYLIGWLVHNKEIIKELEELGIQTKDDKNHSRSEIIDSIEIKDKNNPPIVIFSAHGTDQKTIDKAREKGLVVFDTTCIYVTKTHDLIKEKIEQGYQIFYIGVNNHPETISTLSIDKSIILIETVNDIENIRTESEKPIFVTNQTTISIYEFEEITETLKSKYKNIEFKNDICNAAKDRQDAVINMPSEVDLLLVVGDIKSNNSKKLVEIGIKKQIESHLIWNTKNIKDEWFINKKCLAITSGCSTPTWLANYVIIFLEKKLGTAND
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MSD4_XENTR
Sequence: MKQLKRKRKSNFSVQETQTLLKEIKKRRDIIFSKQLNTTINEMKRKAWEEIAECVNALGEGEQRTGTEVKRRYLDWRALVKRKRLNSDVKLGGSAFHLPLSDLDDSINDDTDDKPSVLTSESSLEWKNVADVREASESMTEIKVEEEEDPQGFEGPSWKKRVSHPCLGIQLNARQNRILYNKTPSDEQFEIEEEDEMLSTVLPDSREENDLPEEFPRIEEFGTLSSIARIPYKESHLLVTLEKQKLELERQRLSIEAERLQVEKERLQIERERLRHLDMEHERLQLEKERLQIEREKLRLQVMHAEKPNLENDFAQSEKTVLQPLDIEAEKLKLEREHLQLEKERLQLLKFEFEKLHIEKERLQDALHLTFKHIPASCVACDLQDSQIHSATTFDGIKEKTNTLVPGS
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 4.
Protein: GALE_PONAB
Sequence: MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKHSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
What is the function of this protein?
Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.  The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate.  It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited.  Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: SAS6_CHICK
Sequence: MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQSLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQEDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKENGDNLGLESKYFKKKEDSIPLRGLSQNTLNSENLKPYLPKVQPSLPAAVTTTSAYFPG
What is the function of this protein?
Central scaffolding component of the centrioles ensuring their 9-fold symmetry.  Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (By similarity).
What are the official names of this protein?
Spindle assembly abnormal protein 6 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity).
Protein: HSP12_SOYBN
Sequence: ILQISGERNVEKEDKNDTWHRVERSSGKFMRSFRLPDNAKVDQVKASMENGVLTVTVPKEEIKKPDVKAIEISG
What are the official names of this protein?
Class I heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_STRAW
Sequence: MPELVFFSGTMDCGKSTLALQIGHNRSARGLQGVIFTRDDRAGEGKLSSRLGLVTEAVEAAPGMDLHAYLVDQMSKGGKVDYLIVDEAQFLAPEQIDQLARVVDDLDLDVFAFGITTDFRTKLFPGSQRLIELADRIETLQVEAMCWCGARATHNARTVGGEMVVEGEQVVVGDVNRPAAEVGYEVLCRRHHRRRMTSASAYAAAISPDVLPVTSA
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.