PharMolix/UniProtQA huggingface dataset:
Protein: ARGJ_STRT2
Sequence: MKVIDGTIASPLGFSADGLHAGFKKRKMDFGWIVSEKPASVAGVYTTNKVIAAPLIVTKTSVKKAGKMRAIVVNSGVANSCTGTQGLEDAYTMQEWTAEKLGVEPDMIGVASTGIIGELLPMDTLKNGLSKLVVNGNANDFAKAILTTDTATKTIAVTETFGRDVVTMAGVAKGSGMIHPNMATMLGFITCDANISSDTLQLALSQNVEKTFNQITVDGDTSTNDMVLVMSNGCALNDEILPDTPEFDKFSKMLNFVMQELAKKIAKDGEGANKLIQVDVVNAPNALDARMMAKSVVGSSLVKTAIFGEDPNWGRILAAVGYAGVDVPVDNVDIMIGGLPVMLASSPVTFDDEEMKDIMHGDEVTITVDLHSGQEKGTAWGCDLSYDYVKINALYHT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_LISW6
Sequence: MTKVYYEDAVKNNALEGKTVAVIGYGSQGHAHSQNLRDNGNNVIIGIREGKSAESARNDGFDVYSVSEAAEKADVIMILLPDETQGETYENEIKPNLKAGNSLVFAHGFNIHFDVINPPNDVDVFLVAPKGPGHLVRRTFVEGGAVPSLFAIYQDATGNARETALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGATHLIQAGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMEKMRHSISNTAEYGDYVSGPRVVTADTKKAMKEVLTDIQNGNFAKSFIDDNKNGFKEFHRMRKEQQGHQIEKVGAELREMMPFVKPQH
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YIDC_PROMP
Sequence: MIGFISEKLLIPILDFFYGLVPSYGLAIVALTVVIRIALFPLSAGSIRSARRMKIAQPVMQKRQAEIKSKFSSDPKKQQEELGKLMNEFGSPLAGCLPLIVQMPVLFALFATLRGSPFADVPYNINLKVLPQDQIAAIDPKPYKSPRHSIFVTEKSHFPVIATLPNGTKLGSEESVKINLQTTNGNNYSEVLSNYDNGSRFLPTWTVSKGSENIKVSQDGLVTAIKPGDATIEAKIPGLAAKSGFLFIKALGQVGFYVDGSINWDIATLVGAFGLTLLLSQVLSSQGMPSNAQQSTANKITPVMITGMFLFFPLPAGVLLYMVVANIFQAFQTFLLNKEALPANLQKILDDQLTGKNKVIPSTANISDKRLPFEPNNKK
What is the function of this protein?
Probably also aids protein insertion, folding and/or assembly of membrane complexes destined for the thylakoid.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEP6_ARTBC
Sequence: MRFSVLLTGLAAAGSIATAERTCGAVPPRAYEKEFTEALNSLSPEAASADLTAGITIDTYLHVLTSGQTGNIPDSQLQAQINAMNQHYSQAGVQFKLVKATRTDNANWASGRDEAGMKKALHMGTYSSLNIYFIPNLSSGLLGICYFPRANPSQTTIIMDGCMVRSGTVPGGETTNYNQGKTATHEVGHFLGLYHVFSENGSCVDADMVADTPAQSKKTSGCPSSQDSCPGGGVDSIHNYMDYSYDVCMNQFTPGQANRIAQSWRAFRAGH
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity).
What are the official names of this protein?
Extracellular metalloprotease ARB_05317.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
Protein: MYB34_ARATH
Sequence: MVRTPCCKEEGIKKGAWTPEEDQKLIAYLHLHGEGGWRTLPEKAGLKRCGKSCRLRWANYLRPDIKRGEFSPEEDDTIIKLHALKGNKWAAIATSLAGRTDNEIKNYWNTNLKKRLKQKGIDAITHKPINSTGQTGFEPKVNKPVYSSGSARLLNRVASKYAVELNRDLLTGIISGNSTVAEDSQNSGDVDSPTSTLLNKMAATSVLINTTTTYSGFSDNCSFTDEFNEFFNNEEISDIYTTVDNFGFMEELKSILSYGDASAGVIENSPEVNVADAMEFIDSWNEDDNMVGVFV
What is the function of this protein?
Transcription factor involved in tryptophan gene activation and in indole-3-acetic acid (IAA) and indolic glucosinolates (IG) biosynthesis.  Acts as a direct transcriptional activator of both Trp synthesis genes and Trp secondary metabolism genes.
What are the official names of this protein?
Transcription factor MYB34, Myb-related protein 34, AtMYB34, Protein ALTERED TRYPTOPHAN REGULATION 1, ATR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIF_HUMAN
Sequence: MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF
What is the function of this protein?
LIF has the capacity to induce terminal differentiation in leukemic cells.  Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
What are the official names of this protein?
Leukemia inhibitory factor, LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor, MLPLI.
What is the protein family that this protein belongs to?
Belongs to the LIF/OSM family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTNN_BACSU
Sequence: MRLAVIGAMEEEVTILRNKLENAKTETIAHCEFTTGEYEGTEVILLKSGIGKVNAAISTTLLLDRYKPDYVINTGSAGGFHHTLNVGDVVISTDVRHHDVDVTAFDYEYGQVPGLPAAYAADEKLISITEEAVSELDGIQVAKGTIATGDSFMNDPKRVEEVRARFSDLYAVEMEAAAVAQVCHQFKTPFVVIRALSDIAGKESHVSFDQFLEQAAVHSTELVLKVIKRIH
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (PubMed:10574451).  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine (By similarity).
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: SECA_MYCPU
Sequence: MIKKLKEIPFFKSTEMKIAEKTLQQINDLEPSVVNLTDEELQNKTDEFVRRIQEGETLEHIRPEVFAVSREATKRVLKKRPYDVQMLGGIILDLGSVAEMRTGEGKTITSIAPVYLNALEKKGVIVSTVNEYLAERDAAEMGEVFSFLKMTVGVNKPSMSPEEKKQIYQCDITYSIHSELGFDYLRDNMVTNINDKVQRGLNYILLDEVDSILIDEARTPLIISGGESSSSYMYEVANQFARTLQPGDYEIDEESKTIKLVDSGIDKANKFFTLSNLYDIKNSELVHRIQNALRANFIMKKDVEYIVKDEKIELIDAFTGRIMEGRAYSEGLQQAIQAKEFLEIESETKTLATITYQNFFRMFKKLSGMTGTAKTEEQEFIDIYNMRVNPIPTNLPNIRVDDEDSIYWGTRQKLNAILKEVKQVSKTGQPILIGTSQIEQSEQLHQLFDQNGIVHTVLNAKQNEQEANIISQAGQLNAITIATNMAGRGTDIKPSKEALAVGGLYVLGTDKSESRRIDNQLRGRSGRQGDIGYSKFFLSLDDQLILRFAGADKLKEIFPKSEEALNSKQLKRHFSNAQKKIEGFNYDSRKTVLNYDDVIRQQRELMYSQRDLILVSEDLLFVIERMVFRSVDDVLKNSMFLLKNGGFDYTKLTEYINDQWLKPFDFKFEESKLSHLHEKDLAEYIFQNLMEQYMIVRQRLIDSFGEDSILYHERSILISTIDSYWQNHINSMDKLRSNSNMVQYAQKNPYQVYTQKGSKKFERLIVEIALQSSVKLFNNPSAYRQDQMEEVMIEGYTQEFIDKIPESEREYFKTLPQDLKSKIVKNLIQLEQSIAMVESNDQSQDLQSITIDILPDQNLNNSSDEAK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: AROC_VIBVY
Sequence: MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEISEADLQTDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIRAYLSQMGDVAIDKVDWNEIENNPFFCPDVDKVEAFDQLIRDLKKEGDSIGAKIQVVATNVPVGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVSQKGSQHRDTLSPQGFGSNHAGGILGGISTGQDIVANIALKPTSSITVPGDTINVDGESTQLITKGRHDPCVGIRAVPIAEAMLAIVVMDHLLRHRGQNHGVSTQTPKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: EFM5_YEAST
Sequence: MSDSDSDSDYELTLSANALAALEEFKREEQQHQEAFQKLYDETDEDFQKKKKEEGMKLFKEDWQLSQFWYSDDTAAILADAILEGADENTVIAIVSAPSVYAAIQKKPTNEIPTEHIYLFEFDKRFELLAGRDHFFFYDYNKPLDFSDEIKGKVDRLLIDPPFLNEDCQTKSSITAKCLLAPNDNSKTKKGVFKHRLISCTGERMSEVISKVYSDTRITTFLPEHSNGLSNEFRCYANFECSSWKFAS
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-79' (PubMed:25446118).  Required for replication of Brome mosaic virus (BMV) (PubMed:14671320).
What are the official names of this protein?
Protein-lysine N-methyltransferase EFM5, Elongation factor methyltransferase 5, N(6)-adenine-specific DNA methyltransferase-like 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_PSEPF
Sequence: MHALQAKILDPRIGTEFPLPQYATPGSAGLDLRAMLQEDIVIKPGETVLIPTGLSVYIGDPNLAALILPRSGMGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRGQTEFTMPVGERLAQLVLVPVVQAHFEMVEEFVETERGTGGFGHSGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: NUP62_ARATH
Sequence: MSGFPFGQSNSVGGFSFGSSSATNSSSASSTTSPLSFSFNQSSNPSSTGFGFGSSVSSTPASSTTPSFGFGASSTPSFGFGSSASSSTPSFGFGSSASVTPASTTPSFGFGTAASSSAPAPSLFGSSTTNASSAAPGSSPFGFVTSSASSTATPSSSLFGAPASSAATPSSSPFGAAPASGSTPLFGSSPSLFSAPSSASASNSSLFGASSSAATSTSPLFGAPSSATGATPSFSVASSAPGSSSSIFGATGSSPSFSVASSASGSSPSIFGATGSSPFFGSSSSAGSTPSLFASSSSGATTSSPSPFGVSTFNSSSTSNTSNASASPFSASTGFSFLKSTASSTTSSTTPSAPPQTASSSSSFSFGTSANSGFNLSTGSSAAPASSTSGAVFSIATTTTTSSSTPAATSAPASSAPASTMAFPSFGVTSSATNTTPASSAATFSTTGFGLASSTPATGSTNSFTGFAVPKTSTPASSSQPQTTSPAFSFSLPSSTSTTAPATSSATTTQTTLVVPSSSGTSTAVAPVAGSPKLPSEITGKTVEEIIKEWNTELQERTGRFRKQANAIAEWDKRILQNRDVLLRLEIEVAKVVETQSSLERQLELIETHQQEVDKALQSMEEEAERIYNDERKSLLDDEAASTRDAMYEQSELVERELEHMTEQIRSIIQSVNANQGGELEAIDGMSPLDVVVRILNNQLSSLMWIDEKAEEFSSRIQKIALQGSGGDRELMAPKHWMS
What are the official names of this protein?
Nuclear pore complex protein NUP62, Nucleoporin 62, NP62, Protein EMBRYO DEFECTIVE 2766.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin NSP1/NUP62 family.
Protein: ARGD_XANAC
Sequence: MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPDLVAALTEQAGKLWHTSNVFFSAPPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRKWASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEGYEPLPGGFRYVDFNDVAALEAAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLFAHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAQTMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVVRQSAALRAGLEALNAEFGLFAQIRGRGLMLGAVLAPEHAGQAGAILDLAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLATAEYVAQP
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_PYRNV
Sequence: MVMLDLLSNALIQIKNAEAMGKRQVAIWPVNKLIYYTLRVLQRHGYVGEVEYIDDGRGGKYVVQLLGKINDIGPIKPRYPVKYREIVQWEQKFLPARQIGILVISTNQGVMSHVEAKEKKIGGVLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PANB_PARP8
Sequence: MTYLQETSRSAVTVPKLMAMREAGEKIAMLTCYDASFAALLDRAGVDSLLIGDSLGNVLQGQSTTLPVTLDEIAYHTACVARAKPSALIVSDMPFGTYGTPADAYANAVKLMQSGAQMIKLEGGEWLADTVRFLVERSVPVCAHVGLTPQSVHAFGGFKVQGKTESGAAQLLRDSRAMQDAGAQLLVMEAMPTQLAAEVTKQLRIPTIGIGAGVDCSGQVLVLHDMLGIFPGKRPRFVKDFMQGQPSILAAVEAYVRAVKDGTFPGPEHTF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC42_MOUSE
Sequence: MAYYLNSEAHLDPGPIYVRENGQLHMVNLALDGVKNSLQKPRPFRLFPKGFSVELCMNREDDTAQKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVVAEKLEEIKSFRELTRLDLSCCWLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGIRKMTAPVRVMKRGLENLALLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKAVKDKLRANIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVSVEAVRQRKDVEPRKAAQYFYQNRARTEVTRKCPLAETHMNSSGKLQFYREEAPDCHEPLLSQESKKSKKRAFKESEQEQSSPQSAKQKCVCLAVEDWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.
Protein: NQRF_CHLPN
Sequence: MTWLSGLYFICIASLIFCAIGVILAGVILLSRKLFIKVHPCKLKINDNEELTKTVESGQTLLVSLLSSGIPIPSPCGGKATCKQCKVRVVKNADEPLETDRSTFSKRQLEEGWRLSCQCKVQHDMSLEIEERYLNASSWEGTVISNDNVATFIKELVVAVDPNKPIPFKPGGYLQITVPSYKTNSSDWKQTMAPEYYSDWEHFHLFDQVIDNSQLPADSANKAYSLASYPAELPTIKFNIRIATPPFINGKPNSEIPWGVCSSYVFSLKPGDKITVSGPYGESFMKDDDRPLIFLIGGAGSSFGRSHILDLLLNKHSKREIDLWYGARSLKENIYQEEYENLERQFPNFHYHLVLSEPLPEDIAAGWDKDDPTKTNFLFRAFNLGQLSRLDNPEDYLYYVCGPPLHNSSILKLLGDYGVERSSIILDDFGS
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CARA_ASPNC
Sequence: MFARVFKAMPARAPAFTSVNASIQSRFMATVRQGRPATERATFTIRDGPIFHGKSFGARSNISGEAVFTTSLVGYPESLTDPSYRGQILVFTQPLIGNYGVPSAERDQHGLLKYFESPNLQAAGVVVADVAEQYSHWTAVESLGEWCAREGVPAISGVDTRAIVTYLREQGSSLARITVGEEYDADQDEAFVDPEQIHLVRQVSTKAPFHVSAADPQCHVAVIDCGVKENILRSLVSRGASITVFPFDYPIHKVAHHFDGVFISNGPGDPTHCQDTVYHLRRLMETSQVPIFGICLGHQLLALANGARTIKLKYGNRAHNIPALDTTTGRCHITSQNHGYAVDASTLPSDWKPYFVNLNDSSNEGMIHKTRPIFSTQFHPEAKGGPLDSSYLFDIYLDSVVKYKNHQLAFHPNRNTVPSPLLVDLLAKERVGVQPTIGMQNVAAAAAAAVAAA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, CPS-A, Arginine-specific carbamoyl-phosphate synthetase, glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_LISMO
Sequence: MEKCEGIVIRQTSYRESDKIVRMYTREFGKIGVVARGAKKTKSRLAAVTQLFTNGYFTFFGGNGLGTLQQGEVIETFSSIQQDIFMTAYATYVCELLDKATEERQPNPYLYELTFQILRDIDEGYDPQILTQIYEMKMLPVLGLYPTMDKCAICGETTGHFDFSTSSNGIICHRCFEKDRYRMHLPENVVKLLRLFFIFQLDRLGNIDVKQETKDWLQKAIDTYYDEYSGLYLKSRKFIREMDKWENMLKKDSDD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TRHR_CHICK
Sequence: MENGTGDEQNHTGLLLSSQEFVTAEYQVVTILLVLLICGLGIVGNIMVVLVVLRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITESLYKSWVYGYVGCLCITYLQYLGINASSFSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWSFASVYCMLWFFLLDLNIAVYKDTTVVSCGYKVSRSYYSPIYMMDFGIFYVLPMVLATVLYGLIARILFLNPIPSDPKENSNTWKNDMAQQNKTVNSKMTNKSFNSTIASRRQVTKMLAVVVVLFAFLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCHLKRDKKPANYSVALNYNVIKESDHFSSEIEDITVTNTYLSSAKTSIGDTCLSSEA
What is the function of this protein?
Receptor for thyrotropin-releasing hormone (TRH).  Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
What are the official names of this protein?
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FTHS_SYMTH
Sequence: MLSDIAIAQRARLEPITKVAEQIGLGPEDLELYGRYKAKVADHVWPRVRSNPDGKLILVTAISPTPAGEGKTTVTVGLGQAMSRIGKRAIIALREPSLGPAFGVKGGAAGGGYSQVVPMDEINLHFTGDFHAVTAANNLLAAMIDNHLHQGNKLGLDPRQITFKRVLDMNDRALRSVVIGLGGKNGGVPRQEEFMITPASEVMATLCLAEDLADLKRRCGEIIVGYTYDGAPVRARDLKAEGAMATLLKEAIKPNLVQTLENTPAFVHGGPFANIAHGCNTVVATRLALKLADYVITEAGFGADLGAEKFIDIKCRLSGLRPDAVVVVATIRSLKMHGGLKKDDLAREDLEALQRGSANLMRHLRNVTEVFGLPAVVAINRFAADTEAEIALLRALVEEAGATAVVADVHARGGDGGIELAQRVVELVEQPNRFRFAYDDEDSLKTKIEKVATRIYGADGVDFTREASRMLKKLESEGFGRAPVCIAKTQYSFSDDPKKLGAPTGWRLTVREVRPSAGAGFVVALTGEIMTMPGLPPVPAAESIDVSDDGEITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RL15_DESA1
Sequence: MVVRKGKKSRKLQGRTRTMGWGRVGQHRKSGSRGGFGAVGFHKHKYIWIIKHAPNWYGKHGFRPRSRIHENVTINVGELDELAWRLASNGKAIIEDGLIVLNTVEMGFDKVLGSGKVTRGLKVIAREITEEAKRKIEEAGGKVILLEELEAGSAT
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: KAD_BACAN
Sequence: MNLILMGLPGAGKGTQAEQIVAKYNIPHISTGDMFRAAMKAETEMGLQAKSFIDKGALVPDEVTIGIVRERLSQEDCVRGFLLDGFPRTVAQASALEEIMKDLGKKIDYVLNINVDSGLLLKRLTGRRICKECGATYHLEFNAPAKADVCDKCGGELYQRSDDNEETVANRLDVNIKQTKPLLDFYEELGYLQSINGEQDINKVFADIDVLIGGLA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_PROMM
Sequence: MDSPSTTANGWIDEHHQGVRYGLQGRVLVDETSPYQRITVIDSSRYGKGLLLDGCWMTAEHQERHYHESLVHPALCSAAQLERVLVIGGGDGGTARECLRYQDVKHLDMVEIDRRVVELSQKHLPSLGSHAWSDPRLQLNLENGIAWVANATESSYDVILIDGSDPAGPAEGLFNQTFFEHCRRILRPGGVFATQSESPEAFRQVHIDTVRLIRQVFGYADPLYGWVPMYPSGWWSWTFAAIDGPRYRNPLPARAAAISAGCEIWSPRWQQGAFEAIPAFIERELT
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIN1_PONAB
Sequence: MVRSGKNGDLHLKQIAYYKRTGEYHPTTLPSERRGIRRAAKKFVFKEKKLFYVGKDRKQNRLVIVSEEEKKKVLRECHENDSGAHHGISRTLTLVESNYYWTSVTNDVKQWVYACQHCQVAKNTVIVAPKQHLLKVENPWSLVTVDLMGPFHTSNRSHVYAVIMTDLFTKWIVILPLCDVSASEVSKAIINIFFLYGPPQKIIMDQRDEFIQQINIELYRLFGIKQIVISHTSGSVNPTESTPNTIKAFLSKHCADHPNNWDDHLSAVSFAFNVTHLEPTKNTPYFQMFSRNPYMPETSDSLHEVDGDNTSMFAKILDAIKEADKIMENKTTSLGQMENNNLDELNKSKIIVKKKPKQLNPFHLKVGHEVLRQRKNWWKDGRFQSEWVGPCVIDYITESGCAVLRDNTGVRLKRPIKMSHLKPYIRESSEQESLYLLQGSVVADHDYIGLPEIPVGAYQANILVEDATIGIVDNELLTSSKDRELLEYRNTKVSPLIDDHSSLEKQTFSLLDSSNQVLEYLS
What are the official names of this protein?
Gypsy retrotransposon integrase-like protein 1, GIN-1.
Protein: FPG_ECOUT
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SYC_RHIL3
Sequence: MDATPELKLYNTLTREKSVFSPIDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRYVYGEDHVTYARNITDVDDKINARALRDHPGLPLNDAIRAVTEKTETQFHADVAELGCLEPNFEPRATDNIVEMTEIIEKLIGNGHAYVASGEVLFDTKSMADYGQLSKRPLDEQQAGARIAVDAHKKNPGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGLDLIFPHHENEIAQSRCAHGTEVMANVWMHNGFLQVEGRKMSKSEGNFVTIHELLQTETFGGRKWPGQVLRLAMLMTHYREPIDFSIKRLEEAERLLAKWPAAEASDAAPDESVLNALSDDLNTVAAVQALHALAQAAHGDPTARAVFAATADLLGLLPKKMEIDEAVASAVDALVAMRLEMLKAKNFTEADKIRDELTAKGIQLKDGKDAVTGERVTTWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMC2_METMA
Sequence: MTNTEIFNKLTNAIVTQDIAGCAKLTQEALDAGISPLDIITKGLSPGMKIIGDKFEAAEIFLPQIMMSGKAMSSAMEILTPELEKTKVEGEEGTGLAITFVAEGDIHDIGHRLVTTMLGANGFDILDLGVDVLNETVIEEAAKRKGQKIILVGSALMTTSMLGQKDLMDRLREENLRDSVKCMFGGAPVSDKWIDEIGADATAENAAEAAKVALNVMK
What is the function of this protein?
Acts as a methyl group carrier between MtmB and MtbA.
What are the official names of this protein?
Monomethylamine corrinoid protein 2, MMCP 2.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.