PharMolix/UniProtQA huggingface dataset:
Protein: NUOA_ACISJ
Sequence: MNLDQYLPVLLFILVGIGVGVVPLLLGYVLGPNRPDPAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFPWAVTLQEVGVTGFVAVLVFLAILVVGFAYEWKKGALNWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TOLB_BLOPB
Sequence: MYLIIKKTHKLPHWLQKVSLSIMLIIFLWKPALLADMHIEITCGVNAAHPIAVIPFTCVSNQYNKSISIEDIASIIAADLRNSSKFNTIPVEYLPHKPTKVSDVIPTFWEKLGINIIVLGTVHINYDESYIISYHLIDTSSNPALIISENQYSVEKKWLRYVAHAISNEIFEKLTGIKGAFCTRIAYVLRIHNDHYPYELYISDYDGHNQISICRSTEPLMSPAWSPDGKKIAYVTFASGHSELVIQALNTGLVNNIVSFPGHNGAPSFSPDCKKLAFSLSKTGSLNLYIMDLESGEITQLTKNRNNNTEPSWFPDNQNIAYTSDQGGSPQIYKINVKTTEIQRLSWLHTSNQNPNVSSDGTFIIMVNRHQGKQNIAKLNLLTGQEEILTDTLLADSPSIAPNNTMVLYSNINKDLTTKSNLELISIDGHFKAHIQGDQGDIRFPTWSPLHLE
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FUMC_BRUSU
Sequence: MAATRTETDTFGPIDVPADRYWGAQTQRSLQNFRIGGERMPLPLVHALGVVKRAAAETNIALGKLDPVLGQVIAVAASEVIEGKLDDHFPLVVWQTGSGTQSNMNANEVISNRAIELLGGEMGSKKPIHPNDHVNMSQSSNDSFPTAIHIATAVETVNRLYPALEHLTKALKVKEEAFKDIIKIGRTHTQDATPVTLGQEFSGYRAALEYARHRLEQSLADVFLLAQGGTAVGTGLNAPVGFDKGFAEAVSEITGLSFKTAPNKFEALASHGAVLNFHGSLNALAADLFKIANDIRFLGSGPRSGLGELSLPENEPGSSIMPGKVNPTQAEAMTMVATQVFGNQTAVTVAASQGHFELNVFKPVIAYNVLQSIRLLSDTMVSFADHCVEGIEPNTARIKELLERSLMLVTALAPAIGYDNAARIAKTAHKNGTTLREEALASGLVSEEDYDRLVRAERMIAPQ
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXC2B_XENLA
Sequence: MMQARYSVADPNALGVVPYLSEQNYYRAAGTYGSMATPMSVYPAHEQYTPAMARSYGPYHHHQQAAPKDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFENGSFLRRRRRFKKKDASREKEDRLLKDQGKVQGPVPSLELPKHEKKIIIKSESPELPVITKVENLSPGGGSAMQDSPRSVASTPSVSTDSSIPEQHPASNGFSVDNIMTLRTSPHGDLSPVPAIPCRTAMVSSLPINYTAHTQSSVYSQACTQSMDTSGSFQCSMRAMSLYTGDRPSHMCAPSTLEEATSEHHNGTSSPLNSMSQESVLTSSHHQQTATGGQTAAPWYLNPGADIGHLSGHNFGSQQQTFPNVREMFNSHRLGIESSALSEHQVSGNTNCQIPYRSAPSIYRHSSPYAYDCTKY
What is the function of this protein?
Transcriptional activator.  May be involved in the dorso-ventral patterning of the mesoderm (By similarity).
What are the official names of this protein?
Forkhead box protein C2-B, FoxC2-B, FoxC2b, Fork head domain-related protein 4', FD-4', xFD-4', xFD4 B.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGDC_SULAC
Sequence: MSQQLSSQTPSNQDRIVGKHVFGNLYDIDDKLLMDKDLLEGLVLEAVKIAKMNLVEIKSWSFGGKKGGVSVIALVEESHIALHTWNEYKYATLDVYTCGVDSNPQAAFEFIVSNLKPKRHQMFFADRSSE
What is the function of this protein?
Specifically catalyzes the decarboxylation of L-arginine to agmatine.  Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.
What are the official names of this protein?
Arginine decarboxylase proenzyme, ADC, ArgDC, Pyruvoyl-dependent arginine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: M770_ARATH
Sequence: MGLSTHCQLVFSWKPMNTHMVSRAMEGSLKSYPFPSNINITSCVSIKLNDRNYLLYDEGRVRLSLLNLGERCDFVPFLSVELFKPLQSSGVYEKLHESNN
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00770, ORF100b.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GYRA_STAAM
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDLSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMKSLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDIQQSSDEDEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFLE_ECOLI
Sequence: MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDLLYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGEVKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETCLHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIRVPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLDAPELLDFAQQYACQKGLTATLRG
What is the function of this protein?
Activation of pyruvate formate-lyase 2 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Putative pyruvate formate-lyase 3-activating enzyme, Formate-C-acetyltransferase-activating enzyme 3, PFL-activating enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_TRYB2
Sequence: MSDIIRIKRHFYVHLLNNNTNVTKCMLGPQVYTRKEHERCLFEPRQCVVVPPGHYCVVQNPCVRGEDNIPKVGESEEVQLRMGEKEIRFEQPPFPLLPGEELLTVDGEWLFKLKVIPSNKGYHVRCTRDFVDSTRVSVRAGEQWIVEGPQTFIPRVEVEELGEVEALTVESNTAIKLRARLNFTDRQGVARVAGEEWLHRTSGAYLPAYEEEFVSYVRGAVLTEKEAIHLRALRNFTDVYGKARKAGEQWMITHKMSSTHIPDVNEVITATVNAIILSKNQYCIVKDPVGDEGINQFGKREVRKGECSFFLRPGESLVGEVQSMNAIGKNEALLLQALEKFEDCGGTVRMPGEKWLLRGATEYIPRVDVCVLERRGVIALDKNEGIYVMNTTTGEVRTVIGEPYMLKEHEVLWEKDLSPDVEELLACPTGCCRCSERDPNFTSSRVKHRIIRFNVQHNAAVQIYDYKQKKPRVVLGPNLVMLSPDEEFTVLSLSGGKPKALNSLLALQLFLGPRFSSDTIVVETSDHARLQLSLSYNWHFDVNRENPDAKIFSVPDFVGDCCKTIASRVRGAVAAEDFDSFHRNSAKIIREAVFGRDGNGHVRNSLRFSANNLVVTNIDIQSVEPTDAKTRDSLQKSVQLAIEITTKSQEAAARHGKERKDQEARGRLERQKLVDKIEVERTKTQWLELQAQSEVVQASGQAVAEAKAKAESLLIEADTELKQAEMRAKALRITAASDLAKQKQQQDLELEFAKRQNELEIVKARELAQTEVERIQRMVSAIGRQTLVSIAQAGPEMQAKLLGGLGLKGYLITDGKTPVNLFNTAQGMLGGQTTETKS
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
What are the official names of this protein?
Major vault protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: O16A_CONST
Sequence: MKLTCVMIVAVLLLTACQLITAEDSRGTQKHRTLRSTARRSKSESTTRCRSSGSPCGVTSICCGRCYRGKCT
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  In vivo, this toxin is a potent paralytic toxic in lower vertebrate species, but it is much less effective in mammals.
What are the official names of this protein?
Omega-conotoxin SVIA, SNX-157.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NU4LC_CRUWA
Sequence: MILEHVLVLSAYLFLIGLYGLITSRNMVRALMCLELILNAVNMNFVTFSDFFDNSELKGDIFCIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSTLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PCN_ARATH
Sequence: MLEYRCSSVDWKPSPVVALANSSDDSQVAAAREDGSLEIWLVSPGAVGWHCQLTIHGDPNSRISSLAWCCSPSIGLPSGRLFSSSIDGSISEWDLFDLKQKIVLESIGISIWQMALAPISGFSSDVEGIKNGYLSEKSNDEEEIGSEEDGSDSDEFHEKSEEEIDRILAAACDDGCVRLYRISNLEKLTYYRSLPRVSGRALSVTWSPDAKRIFSGSSDGLIRCWDATSCHEVYRITAGLGGLGSSSEICVWSLLSLRCSVLVSGDSTGTVQFWDSEHGTLLEAHSNHKGDVNTLAAAPSHNRVFSAGADGQVILYKLSGSTNGSQDLKPSSSQKWDYIGYVKAHTHDIRALTVAVPISREDPFPDDILPDKASRKHRKKGKPVDFTYHKWAHLGVPMLISAGDDAKLFAYSIQEFTKFSPHDICPAPQRIPMQMVHNSMFNKTSLLLVQGISTLDILRLNISSDSSGRASTKSLVRVKSRDARKIICSAISNTGSHFAYSDQIGPSLFELKKNEFTKCPWSVSRRRLPELPFAHSMIFSSDCSRLIIAGHDRRIYTIDISSLELVYAFTPSREEHEGEAPTPKEPPITKLFTSSDGQWLAAINCFGDIYVFNLETQRQHWFISRLDGASVTAAGFHPWNNNALVISTSSNQVFAFDVEARQLGKWSLLNTYVLPKRYQEFPGEVLGLSFSPSPNSSSVIVYSSRAKCLIDFGKPVEEDEEYDLPNGNLSKTLEGKLVNLGLKKGKGTNRKRRLDEYQLEGKSNERKNFEILPSNHPVLFVGHLSKNSILVIEKPWMDVVKSLDNQPVDRHIFGT
What is the function of this protein?
Involved in auxin signaling pathway.  Required for embryo development and meristem organization.  Functions in the auxin pathway, integrating auxin signaling in the organization and maintenance of the shoot apical meristem (SAM) and root apical meristem (RAM).
What are the official names of this protein?
WD repeat-containing protein PCN, Protein POPCORN.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_ECOLI
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What is the function of this protein?
Required for ribosomal protein S1 to bind to the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S2, Small ribosomal subunit protein uS2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: TRUB_CORJK
Sequence: MNQRSARSVLSRSGVVLVDKPSGPTSHDMVAKLRRIMGTRRIGHSGTLDPMATGLLVVGVERGTKFLAHVVTHDKRYEATVRLGVATHTDDAQGDVLSTASPQDLQALTEQQVREAFAAQRGDIMQRPTSVSSIKIDGKRAHELVREGHDVVLPERPVTIFSLEVLDVVVDDATSCIDARISVHCSSGTYIRAIARDVGEALGVGGHLTQLRRTSVGPFDVSEARTLEQLEEDPSLTLNLDEAMVRCFDTREISESEGVDLSLGKWLKPVGNKGVRAAVTPSGQAIALVEEKGKRASSVFVARPAGMD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RGS2_CAEEL
Sequence: MRLLTCDCTFMGQKHSGSVSVEKKNQENDGPPTYEIVFGWSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDFISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVMGTFGIKEEAV
What is the function of this protein?
Weakly inhibits G protein signaling in nervous system, interacting preferentially with the G(O) subfamily member goa-1.  In vitro, it acts as a GTPase activator of goa-1.  Rgs-1 and rgs-2 redundantly adjust signaling when worms are fed to allow rapid induction of egg-laying behavior (PubMed:10950865).  Modulates chemotaxis responses by regulating negatively the sensitivity to quinine in ASH sensory neurons (PubMed:23874221).
What are the official names of this protein?
Regulator of G-protein signaling rgs-2.
Protein: NDHI_MONCO
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CA19_CONLE
Sequence: SDDNDVAAEMMSGLIALAIDSCCSDSDCNANHPDMCS
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Lp1.9.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: POL2_RRVS
Sequence: MSQFWGEFPEKVIQTFQHLQVALIGDIKKCALSSPLFPELSKLDAHSQHHLLASFELPRFGGVTPGVMEQLRDAESELAEAKQRLLRERLHAVANRQNIPYLGDCMYYDAPGISQEELLQAAFLEAPTPAWEHERIRPLWPKDEWFRDARQGPYLEDYGNIPLGDLDTLCLAFDALVEEHWMPIYLLISTFSMFQQYGTQPLLLECAQSAGSLIPACMMTDHHLEPTGDRQADKEARQDYADSQDSIQSMGDFWKEFYTKDSGKKIPDSHKSRLANDPNKVGFTKSALFHKQPLSHSLAQTWANFRGTQDKADLVKVTMDMNIEKYTVRLPDAVRTTAGPLYIEWINLPRMSENSARKLAEVGWNNADICGVDLAVKSHIAVGTPVRVIISLVDGACSDMPTATMCAFEVNLASQNNRSLNLPLLSLPFSRLLADLHDFQNRVKIACQFRDPEGFNVGTPMLSFSSLEFSELKQTAFERNSLLRDSWSEIEKRACHGGGRCVASQGIVQTWEKEVNPPLKEYAPLVLPPVPQPKRNFIDQQTGEVVQSFMQKSRSMRFKSPSDLWSRPSVDGGSTSTQPPSKGSLRCENVPGCAYEVDPLHLLYYESVDVPKDTLAGTLLARIDVRAKAAIFDSAVWRQWVRDGCLKPKIKMRITAATSCFSGIVLGACFDAYRRIPAATKTGITASLVTGLPNTVWATRDTSEVEWDIDLAAVCGHTFFALEDTFGYMDFLIYVLRGNEITAVADWSIYVSFHVDWTQESMLATLIPTFVWPPKPTDISLLKEVWGPYRFTLDGTEAKESFAIMPGTAILHGQQIVRTFPRVVAAHFRSWTGKVRMSIQEVSSIFLTGTYMVGVSWNATADLADIVTRKHWIVKSNEIFEVDLYCPYGENPTFTGQANGKPFIIVHKLGGIVGPKDSVGTFGFMIHIHGLTGVYKNPTLHSGDRSVGSAWFRINNIADDNLVFNIPGRIEDIIAAAGKYDVTNYVNPTSLLFSVTGLHGGIIRLHITWCPNTTLGESKGTLKYMQYLYHTATENFFGDQATRGIIDQDGFTIDIACGDFFGATRVGLPGEVERLGIYSSNAKSIAEIRVSFEVLSMNFYGSTIKVT
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
RNA2 polyprotein, P2.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA2 polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata (By similarity). Movement proteins are targeted preferentially to calreticulin-labeled foci within the youngest cross walls, where they assemble into tubules. During cell division, they colocalize in the cell plate with KNOLLE, a cytokinesis-specific syntaxin (By similarity). SUBCELLULAR LOCATION: [Protein 2A]: Host cytoplasm. Host nucleus. Note=Cytoplasmic early in infection. Later in infection, it becomes progressively concentrated around the nucleus, where it forms large aggregates (By similarity). SUBCELLULAR LOCATION: [Coat protein]: Virion.
Protein: ILVD_SULIY
Sequence: MPAKLNSPSRYHGIYNAPHRAFLRSVGLTDEEIGKPLVAIATAWSEAGPCNFHTLALARVAKEGTKEAGLSPLAFPTMVVNDNIGMGSEGMRYSLVSRDLIADMVEAQFNAHAFDGLVGIGGCDKTTPGILMAMARLNVPSIYIYGGSAEPGYFMGKRLTIEDVHEAIGAYLAKRITENELYEIEKRAHPTLGTCSGLFTANTMGSMSEALGMALPGSASPTATSSRRVMYVKETGKALGSLIENGIKSREILTFEAFENAITTLMAMGGSTNAVLHLLAIAYEAGVKLTLDDFNRISKRTPYIASMKPGGDYVMADLDEVGGVPVVLKKLLDAGLLHGDVLTVTGKTMKQNLEQYKYPNVPHSHIVRDVKNPIKPRGGIVILKGSLAPEGAVIKVAATNVVKFEGKAKVYNSEDDAFKGVQSGEVSEGEVVIIRYEGPKGAPGMPEMLRVTAAIMGAGLNNVALVTDGRFSGATRGPMVGHVAPEAMVGGPIAIVEDGDTIVIDVESERLDLKLSEEEIKNRLKRWSPPSPRYKSGLLAKYASLVSQASMGAVTRPA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MTND_XANOM
Sequence: MSRLRIFADTNPATPEFDSRDGDAIASELKKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: RF1_STRE4
Sequence: MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTRETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKLDEIVDALVLYDQTQKLESLNNQ
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_LACDA
Sequence: MISKPDKNKLRLKRHRRVRGKISGTAERPRLSVFRSNTNIYAQLIDDVAGVTLASASTLDKSVSKDATKVEQAQAVGKAIAEAGKAKGITEVVFDRGGYIYHGRVKALADAARENGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LEUC_MARMS
Sequence: MSGKTLYDKLWDSHLVQQRDDGSALIYIDLQLLHEVTSPQAFEGLRLAGRKPWRVSSSLATPDHNVPTTKKERISGVDGIEDPVSKIQVTTLDDNCNEFGITEFNMKDIRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVQKKSRNMLVRVDGELSPWVSAKDVVLAIIGAIGTAGGTGYAIEFGGTGIQSLSMEGRMTVCNMAIEAGARVGLIAVDDTTIEYVKGRPYAPKGEHWEMAVEAWKDLVSDKDAQFDEVVVIKAEDIKPQVTWGTSPEMVIAIDEPIPRAEDQKDPVKKEGYARAWKYMGLEGKSMLSDIVLDRVFIGSCTNSRIEDLRIAAQVVKGRKVASTLKQAIVVPGSGLVKAQAEKEGLHEIFEAAGLEWREPGCSMCLAMNADKLGAGEHSASTSNRNFEGRQGFGGRTHLVSPAMAAAAAIAGHFVDVNEFVKH
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ACPH_SALA4
Sequence: MNFLAHLHLAHLADSSLSGNLLADFVRGNPATHYPPDVVEGIYMHRRIDVMTDNLPEVREAREWFRHETRRVASITLDVMWDHFLSRHWTQISPDFPLQAFVGYAHAQVATILPDSPPRFVNLNDYLWSEKWLERYRDMDFIQNVLNGMANRRPRLDALRDSWYDLDAHYDALEERFWHFYPRMMAQAARKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: DKSA_BUCAP
Sequence: MEKEQNKKTSSLNVLAIAGLQPYQKKTDEEYMNEKQMLHFKKILETWKNQLTIEINHTLLYIQDKSTNFPDPIDRAAQEEEFSLELRNRDRSRKLIKKIQETLKKIKDKDFGYCNSCAVEIGIRRLEARPTANLCIDCKTLAEIREKQMAG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.  Also required for regulation of fis expression.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.