PharMolix/UniProtQA huggingface dataset:
Protein: KIN20_CAEEL
Sequence: MATMSNDAAAAATWHNNTSTPMDTTEPATNSHNPGETAVIGGPEALLLPSGSGPEEMNRHPLLMAQAHGEHHQPRLLHNFPVIPPPIQQHQQPPLLQQAQPSQIPHPTQPQIDPTMFTQQSGFNWPPIDPNTIAALAQAQLASSHAQFVSLALTLDPTLLSHFLATQQIPPVPQPLVHKKAEMELRVGNRFRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDSKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYKFYNESLEARNNFQQAVPNQRRH
What is the function of this protein?
Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms (By similarity).  Casein kinases are operationally defined by their preferential utilization of acidic proteins (By similarity).  Positively regulates the expression of components of the heterochronic pathway, which regulate developmental timing, such as the transcriptional repressor lin-42 and microRNAs such as let-7 (PubMed:29880558).  Negatively regulates cell cycle exit and cell fusion to prevent the premature differentiation of hypodermal seam cells into adult cells (PubMed:15691769).  Plays a role in regulating axon branching and subsequently, the maturation of the nervous system, most likely by preventing the premature termination of transcripts for proteins such as Ankyrin/unc-44, which are required for maintaining the nervous system (PubMed:31910362).  May phosphorylate ssup-72 to promote nervous system maturation (Probable).
What are the official names of this protein?
Casein kinase I isoform delta, Protein kinase 20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cell junction, adherens junction. Note=Localizes to the nucleus of all cell types and to adherens junctions in the spermatheca.
Protein: ACEA_COPC7
Sequence: MSSERAQFAAEVAEVERWWKSPRFARVNRPYTAADVVSKRGTIKINYPSDVQGKKLWKLLSEHAKNGTPSHTYGALDPVQVTQMAKYLETVYVSGWQSSSTASSSNEPGPDLADYPSNTVPNKVEHLFMAQLFHDRKQREARSRMSDAELANTPVIDYLRPIVADADTGHGGLTAVMKLTKMFVEKGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQYDIMGVENLVVARTDSEAATLITSNIDDRDHPFIQGSTNPSLPPLNNVMVEAEAQGKTGDQLQAIEDGWIKAANLQLFPQALAQALANEGASRSTVEKLVARVSRLSWPQAVAVAQKEFGLKQVPYWNWDAPRTREGYYRYQGGTECAIHRANAFAPYADLLWMETKKPILAQAKEFAAGVHAVHPGQWLAYNLSPSFNWEAAGLNAQDMQAYVWELGKLGFVWQFITLAGLHSNAYISDLFAQNFAKTGMKAYVELVQSREREIGCDVLTHQKWSGADYADSLIKTVTGGVSSTAAMGAGVTESQFTSKL
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: ATPB_SYNE7
Sequence: MVTTTEKTNIGYIRQVIGPVVDVEFPAGKLPQIYNALVIKGKNEAGQDLSVTCEVQQLLGDRKVRAVSMSTTDGLVRGLEVIDTGAPISVPVGEATLGRIFNVLGEPVDELGPVNAATTSPIHRDAPKLTDLETKPKVFETGIKVIDLLAPYRQGGKIGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYQEFKESGVIDEKNIANSKVALVYGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGQLQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPSIVGEEHYRTARAVQSTLQRYKELQDIIAILGLDELSEEDRQTVARARKIEKFLSQPFFVAEVFTGSPGKYVKLEDTISGFNRILNGELDDLPEQAFYLVGDIQEAIEKGAKLKAES
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: FIXB_ECOL6
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLSGKPDDRMIEDYADVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDVAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQFADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA (By similarity).
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: LPTD_ECOL6
Sequence: MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: BBRD_ORYSJ
Sequence: MDNLGHRENGRQRPDQYKGLHTQWMMPQTQRHLKDHQSMNLLALMNDRDNAIRERDHALAEKKAAIAERDMAFTQRDAAMAERNAAVVERDNALAALELARTNGLNMNNGNGFPQGSLSGSKNIHHHDQLSHAQSSPLQLADSPYDHAREMHISEAYPISTAPGSAGKAKRPKKNSSQASPLKRPSGVLRKTKKPSGDWKNVGMSGCGDDSAHASVMKNEWKDQNLGLNQVAFDDSTMPAPACSCTGKLRQCYKWGNGGWQSSCCTMNISMYPLPVMPNKRHARMGGRKMSGGAFTKLLSRLAAEGHDLSTPVDLKDHWAKHGTNRYITIR
What is the function of this protein?
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
What are the official names of this protein?
Barley B recombinant-like protein D, BBR-like protein D, GAGA-binding transcriptional activator BBR-D.
What is the protein family that this protein belongs to?
Belongs to the BBR/BPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYGA_METRJ
Sequence: MSQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQFQVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGELTYGLERLAMYVQGVENVYDLDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDAEGARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAGGAP
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPXL_RHILO
Sequence: MSTTFDKVAKIIADTSEIDIDTITPESHTIDDLGIDSLDFLDIVFAIDKEFGIKVPLEKWTQEVNDGKASTDDYFVMKNLCAKIDALVAAKTA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.  Is involved in the transfer of long hydroxylated fatty acids to lipid A (By similarity).
What are the official names of this protein?
Acyl carrier protein AcpXL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_BURM9
Sequence: MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENFNMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVILGSKNEVERVARYHEQAQS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCKX4_HUMAN
Sequence: MALRGTLRPLKVRRRREMLPQQVGFVCAVLALVCCASGLFGSLGHKTASASKRVLPDTWRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVFTFVNLPMCREDD
What is the function of this protein?
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:12379639, PubMed:26631410).  Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (By similarity).  May play a role in calcium transport during amelogenesis (PubMed:23375655, PubMed:24621671).
What are the official names of this protein?
Sodium/potassium/calcium exchanger 4, Na(+)/K(+)/Ca(2+)-exchange protein 4, Solute carrier family 24 member 4.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: Y4184_BACAA
Sequence: MASETVSNHQEKALALLQADAEKILRLIKVQMDHLTMPQCPLYEEVLDTQMFGLSREVDFAVRLGLIAEEQGKVMLGELERELSALHEAFTNKQQ
What are the official names of this protein?
UPF0358 protein BAA_4184.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: MDTC_SHIB3
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIVGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRAKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFDALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_PETMO
Sequence: MEKILVIDYGSQYTQLLAKRIRDLGVFSEVIQYDDNISLSNVKGIILSGGPDSVYNIDAPDISDEILNAELPILGICYGMQLIAKKLGGKVEQRGIAEYGKTKINITDQSLLFKKIPSTFNVWMSHKDMVTKVPEKFKITSLTSNNIISSFENESENIYCIQFHPEVRHTEFGIDILKNFIQGICGLKGSWTLMDFVENKIKEIKDTIGDKKAIIALSGGVDSSVAAVLTHRAIGNNLKAIFVNHGFLRMNEVEEVESTFRDYMGLNLTTVDAQERFLSKLKGVTDPEQKRKIIGEEFIRVFEQEAKKEEGCEYLIQGTIYSDVIESAKSGKKTFKIKSHHNVGGLPEDIDLKIVEPLKELFKDEVRSVGEILGLPREILYRHPFPGPGLAIRIMGEINDEKLTILKKVDNIFINTLKETGWYDKVWQAFAVLIPVKTVGITGDKRSYGYVAALRSVDSVEGMTADWSKVPFEILDLVSSRITNEVEEITRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DEFD1_SPIOL
Sequence: XTCESPSHKFKGPCATNRNCES
What is the function of this protein?
Antimicrobial peptide.  Active against Gram-positive and Gram-negative bacterial pathogens.
What are the official names of this protein?
Defensin D1, Antimicrobial peptide D1, So-D1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family. Group II subfamily.
Protein: HSP77_YEASX
Sequence: MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNNGNNAESDETKQ
What is the function of this protein?
Acts as a non-catalytic component of endonuclease SceI (endo. SceI), which cleaves specifically at multiple sites on mitochondrial DNA and produces double-stranded breaks.  SSC1 confers broader sequence specificity, greater stability, and higher activity on the catalytic subunit.
What are the official names of this protein?
Import motor subunit, mitochondrial, Endonuclease SceI 75 kDa subunit, Endo.SceI 75 kDa subunit, Heat shock protein SSC1, mitochondrial, mtHSP70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NDK_NEIMA
Sequence: MAIERTISIIKPDAVGKNVIGKIYSRFEENGLKIVAAKMKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEAAEGTIRADFATSVSINAVHGSDSVENAALEIAYFFSQTEICPR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_ACIBT
Sequence: MNKSNRIQTAELDWEFIDGIEVPISKQFGDVYFSKDNGLLETRHVFLNGNDLTERLANLQDFEYFSVGETGFGTGLNILALWQLWQQVRPNNHSHLHAISVEKFPLSKADLIRALNVWDELKPLSKQLIEQYPLPLAGCHRLSFPEERFSIDLWLGDAQDIFPSMVKTKAVNAWFLDGFAPSCNPDMWEQNVLNNIVRLSDYGTTFASFSVAGVLKRGLKAHGIDISRPRGFGHKREMLKAVWKAPVSEEILLEPVSDTLHFTQQHIAVIGAGIAGLSTAWAFAQRGHQVTLFERTAPLSGASGNPLALLNPKLCPIEQSHEHLMTLSWQHALNFYKNFQAFHPIQIQQMALKNAQDLLDLADQYPADIVTQQTSSLESDYPHILLTEAGAVSPHQLRAEILQHPSIELKIANITTFVSFENKVQLKSGNETTLEADHVVVCCARESAALFENYPLLKPIRGQVSWVDNSFATLPLNEAYSYGGYCMQLNTSELILGASFYPNRDDQEVLLDDHVHNFELIHSVFPHYAKQLPPVEQWQGRASVRAQSPDYFPVVGKMQKESRISTFAGLGSKGFLFAPLCSEVLVAQILGEACPVPKSLLQKLDAQRFQKKVKPKKPYFKSQ
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ACIF5
Sequence: MARIAGVNIPNNKQIEIALTYIYGIGRTRARTVLSAADIACDMRVKDISEPELERIRSEVAKFLVEGDLRREVTMNIKRLMDLGCYRGIRHRRGLPVHGQRTKTNARTRKGPAKSITR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NUOA_BURVG
Sequence: MNLAAYYPVLLFLLVGTGLGIALVSIGKLLGPNKPDVDKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFSAMMIFLLEFLLGFAYIWKKGGLDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMJ_AZOVD
Sequence: MADESPAVWVRVEALDTVFHEAAQALAGRLGLPFGGEARFALQLGEQGLQLAELGAQAPGPVRVDFVEGASAHRRLFGGGSGQMIAKAVGVQPGVRPRVLDATAGLGRDAFVLACLGCEVTLIERQPPIAALLEDGLARAVRDPEVAPIVARMRLLPGDAIARMRQWPDEPPQVIYLDPMFPHRDKSALVKKEMRLFRPLVGDDPDAPALLEAALALASHRVVVKRPRKAPSVAGPRPGYSLEGKSSRYDIYARQSLKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDIA_ECOLI
Sequence: MQDKDFFSWRRTMLLRFQRMETAEEVYHEIELQAQQLEYDYYSLCVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSEAQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSAREIPILSDELQLKMQLLVRESLMALMRLNDEIVMTPEMNFSKREKEILRWTAEGKTSAEIAMILSISENTVNFHQKNMQKKINAPNKTQVACYAAATGLI
What is the function of this protein?
Activates cell division by specifically increasing transcription from one of the two promoters that lie immediately upstream of the ftsQAZ gene cluster.  Activates ydiV expression in response to extracellular autoinducer AI-1 (Vibrio fischeri autoinducer oxoC6).
What are the official names of this protein?
Regulatory protein SdiA.
Protein: UXT_DICDI
Sequence: MVSHSHSHTHQNQKDIEKEKLLKERLDSIKYYETFINETLNVDLNKSIEDREKVLENLENYLELKSNIELLIENKMDSMKTMINLGSECYVKARVQDTSYIYVDIGLGIHVKYTLEEAIKFINEKETFLNKTVENQTKKINQIKTKIDLIQNGLKELKHLE
What are the official names of this protein?
Protein UXT homolog.
What is the protein family that this protein belongs to?
Belongs to the UXT family.
Protein: YBEY_BRUA2
Sequence: MSDNAIHIDIMIEAGNWPDEASLESLVSKSVAAAWNNLGLKSATSELSVVFTDDASIQLLNGEWRGKDKPTNVLSFPAFPVKAGSQPGPMLGDIVIARETVEREAKEEGKPIENHLSHLVVHGFLHLLGYDHETDEEAEVMEAREREILHALAIPDPYAVSDEDINND
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURA_BURPS
Sequence: MKKILRFAAVASGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVGLIARRLQQQKAPVPPTDQLRAQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQANGMQLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVDSKITVSDAEVASYIASQRGPNAGSQQDLRLEHIFVKAPANAPQADIDVAQKKAEGLLQQALASGANFERLAKNQSEADDAKKGGDLGFKSPASLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVERRASQNPAASPKIVQTHVRHILLRVGEGKSESQARQQLIDIRRQIESGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNTLQDGQVSNPVRTEYGYHLIQVLGRRDAEGSVQQQMDIARQAIGQRKAEQAYSDWLRELRDSSYVQIKLPVAQ
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: DNAJ_MAGSA
Sequence: MSKQDYYELLGVEKGASPDDIKKAYRKQAMQFHPDRNPGNADAEQKFKEINEAYDVLKDEQKRAAYDRFGHAAFEQGGPGGGGGGGFGGFGGGGFSDIFDEMFGEFMGGGGRRGQSTGRGADLRYNMDISLEDAFAGKTATVKVPSSAPCEDCKGTGGKDGAQPVTCSACHGHGKVRQQQGFFTIERTCPTCQGMGKIIKDPCRSCGGSGRTRKEKTLQVNIPAGVEDGTRIRLAGEGEAGMRGAPAGDLYIFLSIAAHRIFQRDGANIFCRVPIPMTTAALGGTIEVPTIDGSKAKVTIPEGTQTGNQFRLRSKGMSVLRSPARGDMFIQAVVETPVNLTKRQKELLNEFNEAGEGEKAKNSPESQGFFAKVKELWEDLKEG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.