PharMolix/UniProtQA huggingface dataset:
Protein: GUAAB_THEKO
Sequence: MWENFIEEKVKEIRETVGDGKAIIALSGGVDSSTAAVLAHRAIGDRLHAVFVNTGFMRKGEPEFVVKTFRDEFGLNLHYVDASERFFRELKGVTDPEEKRKIIGRVFIEVFEEVAKEINADFLIQGTIAPDWIESHGKIKSHHNVGGLPERLNLKLIEPLRDLYKDEVRELAKELGLPEKIYNRMPFPGPGLAVRVLGEVTPERVAIVREANAIVEEEIEKAGLKPWQAFAVLLGVKTVGVQGDIRAYKETVAVRVVESLDGMTANAMNVPWEVLQRIAFRITSEIPEVGRVLYDITNKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: Y2927_MYCTU
Sequence: MYRVFEALDELSAIVEEARGVPMTAGCVVPRGDVLELIDDIKDAIPGELDDAQDVLDARDSMLQDAKTHADSMVSSATTEAESILNHARTEADRILSDAKAQADRMVSEARQHSERMVADAREEAIRIATAAKREYEASVSRAQAECDRLIENGNISYEKAVQEGIKEQQRLVSQNEVVAAANAESTRLVDTAHAEADRLRGECDIYVDNKLAEFEEFLNGTLRSVGRGRHQLRTAAGTHDYAVR
What are the official names of this protein?
Uncharacterized protein Rv2927c.
Protein: GSH1_PECAS
Sequence: MIPDISEALSWLEKHPLAVKGIQRGIERETLRVTANGDLATTGHPEILGSALAHPWITTDFAEALLEFITPVDKDVDHLLTFLRDIHRHVSRNLGDERMWPLSMPCFIDSEQNIELAQYGSSNVGRFKTLYREGLKNRYGALMQTISGVHYNFSLPLSFWQAREGVADAESGKKAISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLRGRETALPFEHTEKGMLYLPYATSLRLSDLGYTNKSQSNLGITFNDLDTYVAALKRAIKTPSEEYAQVGVKKEGRYLQLNTNVLQIENELYAPIRPKRVTRAGETPSDALLRGGIEYIEVRSLDINPFSPTGVSESQVRFLDLFLIWCALADAPEMSADELLCTRKNWNRVILEGRKPGQTVGMRCETIQQPIAEVGKSLFADLRRVAEVLDAENDQPHYQQVCDELLVGFDDPETTFSGRLLTLMKQEGNGSVGLNLAEEYRQMLSGEPLQVLTEEQLVAEGERSWQRQRQIESEDTMGFDDYLATQ
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: CYC3_SHEFN
Sequence: MSNKLLSALFAAGFAVMMMSSASFAADETLAEFHVEMGGCENCHADGEPSKDGAYEFEQCQSCHGSLAEMDDNHKPHDGLLMCADCHAPHEAKVGEKPTCDTCHDDGRTAK
What is the function of this protein?
Transfers electrons to ferredoxin III.
What are the official names of this protein?
Tetraheme cytochrome c-type, Cytochrome c3.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS2_CHLAB
Sequence: MEEQPLCNLSVKDLMEAGAHFGHQTRRWNPKMKLYIFEEKNGLYIINLAKTLYQLRKALPQVCKVIKENKPILFVGTKKQAKCVIKEAAIEAGEYFVAERWLGGMLTNMTTIRNSIKTLDKIEKDLTQNSSYLTKKEIALLAKRHQKLLKNLEGIRYLKKAPGLVIVVDPSYEKIAVAEAKKLGIPVLALVDTNCDPTPIDYVIPCNDDSLKSIRLIISTIKDSIIDTKKKLGVEIVSPIKTLDIQDSEDMDVYATDEDNRQEDLLAKKYDSNEAN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL4_YERPG
Sequence: MELVMKDAPGALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFSVEAPKTKLLAQKLKDMALEDVLIVTGELDENLFLAARNLYKVDVRDVAGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CYNS_ECOSE
Sequence: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: TCTP2_DICDI
Sequence: MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog 2, TCTP 2.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I54A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIGGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRVNGKWMRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELVRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQKAMMDQVRESRNPGNAEFEDLTFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVLSFIKGTKVLPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDRTTVMAAFSGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKAASPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RS15_PSEPK
Sequence: MALSVEEKAQIVAEYQQAAGDTGSPEVQVALLTANINKLQGHFKANDKDHHSRRGLIRMVNQRRKLLDYLKGKDTTRYSALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: EXO5_CANAW
Sequence: MQRMRGKIFKNEPLVPMNVTSEHEQVQSISKEESRSLSSNDLNLSADSELQLESEPEIESEQLKNHEDVYEIIRSMVLATDTTLPRLSNNSLTGIYNHWKLNPNDDLPLYNPTKYIPYEFHSQYNQDRSYIITPRLSVTKLLVSSWCELRSFYQVYSGSVRLPSTKAMTQGTKLHSKLEAEIHPEIDTTEIEQFLISNAMSLRELQTTVPAEEETVVIDLGEVEQLAVDWAEMLIERLFSLIMGAEAREILLHGYLNLKNRSFVTNKDEIRESSSVLVSGIVDYIKFQNVTNPSDGTLFDDIHGFVDSAFDQVDNVPLVDLSQFLPEAKQILQNYDFRLTFTDVKTRSARQIPRQESVLEAAKFQTFYYRHFFHLLSRDSRFTYFSLIENAERRGHDVDKPLSILTTISLLRKHYHIFFKDFVKLANGEPIGFSPFDDSAKSIPYDFVSMFQSSDEFSLANPNHNHFLEQISAIDGIEYDSILSPLLKVWKTPPTLRYLAARASQLFNVFNENIGDITSVEYRYNKTSELLSEKVYDYNFSEFQAEVESASKFWNGEREVIPTEDLSRCSYCEFQSKCMVAGGKTTEAVEKKTIGPKIRQFLNECESSSKG
What is the function of this protein?
Single strand DNA specific 5'exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PEPQ_ALTSX
Sequence: MNKLAVLYAEHIATLQKRTREIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPVIDNPHCWIVANGTDKPKLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQVEKLLPYDKARFAYIGEYLEVAQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQGHKAARDAFFQGKSEFEIQQAYLLATQHSENDNAYGNIVALNENCAILHYTHFDRVAPATHRSFLIDAGANFNGYAADITRTYDFTGEGEFAELVATMKQHQIALCNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIGLQVHDVGGFMADEQGAHQEPPEGHPFLRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRIEDNIIVHEDSLENMTRELRARLTTHSLRGLSAPQFSINDPAVMSEYSYPSEPLSYEEEIKKSTFIVHVRTRRILVRRRTLSPILIAVTPMPAITAGLM
What is the function of this protein?
Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position and a nonpolar amino acid at the N-terminal position.  Also catalyzes the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds including insecticide paraoxon and nerve gases such as diisopropylfluorophosphate (DFP), O-isopropyl methylphosphonofluoridate (sarin), O-pinacolyl methylphosphonofluoridate (soman), and O-cyclohexyl methylphosphonofluoridate.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, DFPase, Imidodipeptidase, Organophosphorus acid anhydrolase 2, OPAA-2, Paraoxon hydrolase, Phosphotriesterase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: UREE_ALIF1
Sequence: MIKFTHLVHHHHDEHHHNEEHAHNATELTICLTMQERTKSRLKVMLSDGSEAGLFLPRGTVLKEHDIVESDDGVQAMITAAEETVSTVYSDDLLLLAKACYHLGNRHVPLQVEAGWCRYLHDHVLDDMVQRLGLNVKVEQAKYQPEPGAYGGSSAGSHDGHHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET3_SCHPO
Sequence: MSFDPLPGTLENLLEQTSLKWIFVGGKGGVGKTTTSCSLAIQMSKVRSSVLLISTDPAHNLSDAFGTKFGKDARKVPGFDNLSAMEIDPNLSIQEMTEQADQQNPNNPLSGMMQDLAFTIPGIDEALAFAEILKQIKSMEFDCVIFDTAPTGHTLRFLNFPTVLEKALGKLGGLSSRFGPMINQMGSIMGVNANEQDLFGKMESMRANISEVNKQFKNPDLTTFVCVCISEFLSLYETERMIQELTSYEIDTHNIVVNQLLLDPNTTCPQCMARRKMQQKYLAQIEELYEDFHVVKVPQVPAEVRGTEALKSFSEMLVKPYVYPTSGKE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus.
Protein: ASSY_ECO8A
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFD1_NEUCR
Sequence: MSLAKVKHIVLVLSGKGGVGKSSVTTQLALSLSLAGHSVGVLDVDLTGPSIPRMFGIEDAKVTQAPGGWLPITVHEADPSAGVGSLRVMSLGFLLPKRGDAVVWRGPKKTAMVRQFLSDVFWDETDYLLIDTPPGTSDEHISLAENLLQKARPGQLAGAVVVTTPQAVATADVRKELNFCTKTNIRVLGVVENMCGFVCPNCSECTNIFMSGGGEVMANDFGVRFLGRVPIDPQFLVLIETGKRPTYPAGTTVDGKDISTPAGASTSEEEEVKDGSRLVHKYKDCSLAPIFSKITADVISAVQQ
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor cfd1, Cytosolic Fe-S cluster-deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_CHLPD
Sequence: MSFDLPDIILRPASLLYKNIIRIRNRLYDQQIFHTWHSPLPIVSIGNISAGGTGKTPLVDWIVKYYLSLGCKPAIVSRGYGRNTKGVQLVSDGKTVLMKSNACGDETAMLAWNNRDAIVIVAEKRKDAVTFIIRRFAEAMPDVIILDDAFQHRQIARNLDIVVINEKEPYFRADMIPKGRLREPLINLARADLLVLSKITGGSTTAAISMDLEQTGKPVIKAGIAAGNLVCLSGMFNTAKESPVHAGIKALAFAGIGSPQSFIDTLEGQGIQIVSHRFFRDHESYTAKKIAALRLEADEKKLTLVTTEKDYFRMLGQPELQEILHTLSCCYLKIRPEFTEGEKLLKTMLNAVINR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ILVC_PSEU2
Sequence: MKVFYDKDCDLSIIQGKKVAIIGYGSQGHAQACNLKDSGVDVTVGLRKGSATVAKAEAHGLKVTDVASAVAAADLVMILTPDEFQSQLYKNEVEPNLKKGATLAFSHGFAIHYNQVVPRADLDVIMIAPKAPGHTVRTEFVKGGGIPDLIAVYQDASGNAKNVALSYASGVGGGRTGIIETTFKDETETDLFGEQAVLCGGTVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAESRQAMRNALKRIQDGEYAKMFISEGATGYPSMTAKRRNNAAHGIEIIGEKLRSMMPWIAANKIVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PDE9A_PANTR
Sequence: MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCCQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQENFSQMDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
What is the function of this protein?
Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.  Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP.  Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle.  Does not regulate nitric oxide-dependent cGMP in heart.  Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein.  In brain, involved in cognitive function, such as learning and long-term memory.
What are the official names of this protein?
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.
What are the subcellular locations of this protein?
Cell projection, ruffle membrane. Cytoplasm, perinuclear region. Golgi apparatus. Endoplasmic reticulum. Cell membrane, sarcolemma.
Protein: PCP_MYCMM
Sequence: MTKVLVTGFGPYGVTPDNPAQFTAEALDGRTIAGATVVSRIVPGAYFDSIAAAEQAIAEVDPQLVIMLGEYPGRAMLTVERLAQNINDCGRYGLADTAGKVLVGEPTDPDGPVAYHATVPVHEMVLAMRAAGIPADVSDAAGTFVCNHLMYGVLHHIATQNLPIRAGWVHLPCLPMVAALDRNLGVPSMSVETAVAGLVAGIEAAVQHSADTREPVPSRLQI
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_BORBR
Sequence: MEQIPFVSSAPNTLGIELELQLVDPRSFDLAAASDELLAQLANHPIADRVKPEITRSMIELNSSVHEHPAGLLAEMREMRDVLCEAADAVGVGVTGGGAHPFMRWQDRAISDTPRFQYLAEMYGYLARQFTVFGQHIHLGVPSGDAAVRMVRGLSPYVPHFIALSAASPYCEGVDTLFSCCRLNAVNSFPLAGHMPADVTDWYRFEAHLAQLRASGLAESIKDLYWDIRPKPEYGTVEIRVCDTPLTVERACQLAAFAQALAVQVARDPEPSQQAWLAYRSNHFQACRFGLHGSYVTPDGQRVRLVDHLRALFDRLAPVAEELGTGDMLQTLRDEILRNGNDARWLRGQFLKVRELPLVVESMAQNWRGQGVQDTPPSAVRRRIRATSEPVGGVCALSTPQGDPLPGWAERLH
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: VNPA_OXYMI
Sequence: SDSKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKK
What is the function of this protein?
Exhibits vasoactive (PubMed:15652496) and hypotensive activity (By similarity).  Is only weakly active on natriuretic peptide receptor-C (NPR3).
What are the official names of this protein?
Natriuretic peptide TNP-a, Taipan natriuretic peptide, Venom natriuretic peptide OxsSNPa.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_HBVB8
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTAIRQAILCWVELMTLASWVGQNLQDQASRDLVVNYVNTNMGLKIRQLLWFHISCLTFEREVVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVIRRRGRSPRRRTPSPRRRRSQSPRRRRSQSREPQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RBIS_BOVIN
Sequence: MAKNKLRGPKSRNVFHIASQKNFKAKNKAKPVTTNLKKINIMNEEKVNRVNKAFVNVQKELAHFAKSISLEPLQKELIPQQRHESKPVNVDEATRLMALL
What is the function of this protein?
Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production.
What are the official names of this protein?
Ribosomal biogenesis factor.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FLAV_SHIFL
Sequence: MAIHGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDLEAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDALGTIRDIIEPRGATIDADWPTAGYHFQASKGLADDDHFVGLAIDEDRHPELTADRVEKWVKQISEELHLDEILNA
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin 1.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: RL1_BACC7
Sequence: MAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDADYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFRTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PNP_SINMW
Sequence: MFETHKVEIEWAGRPLKLETGKIARQADGAVLATYGETVVLATVVSAKAPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFPEGYKNDTQVIITVMQHDLENNPDVVAMVAASAALTLSGVPFMGPVGGARVGYINGEYVLNPHLDEMDESTLDLVVAGTQDAVLMVESEAKELSEEIMLGAVVFGQKGFQPVIDAVIRLAEVAAKEPREFEPDDHSALENAMLSIAEEDLRKAYKITEKAQRYAAVDAVKAKVKEHFLPEGVENPAHTAEEIASVFKHLQAKIVRWNILDTKSRIDGRDLVTVRPIVAEVGLLPRTHGSALFTRGETQAIVVATLGTGEDEQYVDSLTGMYKENFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPTAEQFPYTLRVVSEITESNGSSSMATVCGTSLALMDAGVPLAKPVAGIAMGLIKEDDRFAVLSDILGDEDHLGDMDFKVAGTEAGVTSLQMDIKIAGITEEIMKVALDQAKHGRVHILGEMAKAISESRGQLGEFAPRIEVMNIPVDKIREVIGSGGKVIREIVEKTGAKINIDDDGTVKIASASGKEIEAARKWIHSIVAEPEVGQVYEGTVVKTADFGAFVNFFGARDGLVHISQLASERVAKTTDVVKEGDKVWVKLMGFDERGKVRLSMKVVDQATGKEIAAEKKDGGEAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.