PharMolix/UniProtQA huggingface dataset:
Protein: HIS7_MYCPA
Sequence: MTAVQAARRARIERRTKESDIVIELDLDGTGRVDVETGVPFYDHMLTALGSHASFDLTVRTTGDVEIEAHHTIEDTAIALGAALGQALGDKRGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHSGEPDHLQHSTIAGSSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSDVPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAJ_METVO
Sequence: MILDILPRVGLKPKDYFLKFVLPAVLASLFMVVLGFIYFDGITRLLVLALPLLLLGGALGYPYIELDSQKQKINERLHVYITKFGVLSITDLDNKALLELLSVEKEELGQLAEESRKIYVLVKRWNQSLAGSCRFLANRTPSSQFGDFLDRMAYSIDSGQELKEFLAGEQDIVMDEYAGFYERALYSLDNFKEMYVSAITSVSFFVTFAIIAPFLLPYDFVTMVTVAIFIFMIIEVILIYSIKNKLPYDRLWHTGEKPTAIDRKLRKWLIISVGLTILASIVLFWGKYIYEAPQLLKIPYELIFSIAMTPLMLGGYMAQREESLVIRKENNFPDFLRSLGDSVSAKGGGTLESLGYLCTNDFGPLTKDLVALHRRLSIRINGQKSWKYFGHDTCSYLIQLFSEMYERCTYLGGNSGQASHIIGKNFRKILRLRRSKYQNVNQFAGVMYGLSGGMALTLFASYGVASMVNGLYSSLDIPDTMLSMVHVVAPSDFGFISYMMYGTLIIYALCSSYLIKLMDGGHYQVSLLHFSTMVWISSIVAVVTEMVTNSLLKATIPV
What are the official names of this protein?
Flagella accessory protein J.
What is the protein family that this protein belongs to?
To M.jannaschii FlaJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Archaeal flagellum.
Protein: Y644_METJA
Sequence: MKVLLKIIVGRAMNILKNFSVPNLCDAGAKPLNGIKPILENQKLVFGEAITVKISYNDWGTLIKTISFAKNKFIVAEVVGEGKYETAVWGGLASLNAKIKGVRGVVIDGCVRDVEDIKALKFPVFAKNFCPNAGKPLNLGEINVAVNCCGVIVEPGDIIVGDCNGVVVIKKESLPEIIENAKNIKEKERKIRERILRGQDLRDVLNLE
What are the official names of this protein?
Uncharacterized protein MJ0644.
Protein: ARNA_PECCP
Sequence: MKAIVFAYHDIGCVGLEALKLAGYEIQAVFTHSDAPGENHFYASVAKAAAEMDVPVFAPEDVNHPLWVNRIRELAPDVIFSFYYRTLLSDDILQLPSFGAFNLHGSLLPRYRGRAPVNWVLVNGETQTGVTLHKMVSRADAGDIVAQSVVEIDDEDTALTLHGKCRTTAAALLAQQLPLIRSREIMLTPQDESQASYFGRRTAADGLIDWQKSAREINNLIRAVTEPYPGAFTFLGERKVVIWRARVLKNDSVKANGVKQEPGSIISTSPLVVSCGEDALEIVSGQSESGLYMSGSRLAAEMGMVPQAKLGNLASRVQRRRTRVLILGVNGFIGNHLTERLLRDDRYEIYGLDISSDAIARFLGDPRFHFVEGDISIHNEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVRYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAKNGLRFTLFRPFNWMGPRLDTLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRIIENRNGQCDGQIINIGNPHNEASIRELGDMLLTSFNAHPLRDRFPPFAGFIEVESSSYYGKGYQDVAHRTPSIRNAKRLLEWEPTVKMEQTVAETLDYFLRTVDPQHADNVTDTQG
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: GLMM_MYCMM
Sequence: MGRLFGTDGVRGVANRELTAELALALGAATAQHLASSTGPGRRVAVVGRDPRASGEMLEAAVIAGLTSQGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDATEDRIESLVAAGPGLRPVGSEIGRVIDAEDAADRYLRHVSKACTTRLDGLTVVVDCAHGAASEVGPRAYRAAGARVIEINADPNGLNINDDCGSTHLEAIRAAVLAHGADLGVAHDGDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELASDTLVTTVMSNLGLHLAMREAGVNVRTTGVGDRYVLEELRAGDYSLGGEQSGHIVMPGLGSTGDGIVTGLRLMTRMVATGASLAALASRMQTLPQVLINVQVTDKAAAAAAPSVQAAVDRAETELGDTGRILLRPSGTEPLIRVMVEAADEEAAHRLATSVADAVSAAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TSAD_THEVB
Sequence: MVRILAIETSCDETAAAVVRDRAIESNVIASQVCAHQPFGGVVPEVASRAHLENINGVITAAISEAGCDWSAIDAIAVTCAPGLVGSLLIGVTAAKTLALVHQKPLLGIHHLEGHLYASYLAEPTLEPPFLCLLVSGGHTSLIGVYGCGEYQLFGQTRDDAAGEAYDKVARLMGLGYPGGPLLDRWAQQGNPEAFDLPEGNIRLPDGKVHPYDASFSGLKTAVARLVAELRQTHPELPVADLAASFQKAVAQALTKRAIAAAVDHGFKTLAIGGGVAANSGLRQHLTAAAEPLGLRLIFPPLRLCTDNAAMIGCAAADHFQRGDRSPLDLTARSRLSLLEISALYGPTPLAVS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_ACIF5
Sequence: MSFQSMASIAEAAREVAAASDLNTLEQIRLRWLGRKGVLTEAMQQLGQLSPETRREAGQLLNERKSEIQSLLQERKAELEAAAIHARLQQERLDVTLPGRREACGSAHPIRQTLEWIEHYFFGLGFETSDGPEIEDDYHNFAALNIPEDHPARAMHDTFYLDATRLLRTQTSTVQIRFLESHQPPLRMIATGRVYRRDSDITHTPMFHQVEGLLLDERASFADLRGLLSDFLHGFFAKPDLPVRFRPSYFPFTEPSAEIDIGCVICGGSGCRVCKQTGWLEVLGCGMVHPAVLAGAGVDGERFSGFAFGMGVERLTMLRYGVNDLRLFFENDLRFLKQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBH_MYCTU
Sequence: MGMNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPAKKATKAAKKAATKAPARKAATKAPAKKAATKAPAKKAVKATKSPAKKVTKAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.  Binds DNA non-specifically.  Induces lymphoproliferation, particularly in health tuberculin reactors, and is immunogenic.  Maybe involved in pathogenesis of inflammatory bowel disease (IBD) in patients with ulcerative colitis and Crohn disease (CD).  Bound by anti-neutrophil cytoplasmic antibodies (pANCA), which are a hallmark of IBD.  The binding is due to pANCA directed against H1-3 cross-reacting with DBH epitopes.  In CD, target of a strong IgA response.
What are the official names of this protein?
DNA-binding protein HU homolog, 21 kDa laminin-2-binding protein, 28 kDa iron-regulated protein, Irep-28, Histone-like protein, Hlp.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PDXT_MYCUA
Sequence: MSIPRVGVLALQGDTREHLAALGEAGAEPMTVRRRSELDAVDGLVIPGGESTTISHLLCGFDLLEPLRARLAAGLPAYGACAGMIMLASEILDAGVRGRQALPLRGIDMTVRRNAFGRQVDSFEGDIAFTGLDHPVRAVFIRAPWVERVGAGVTVLARAGDHIVAVREGSVLATAFHPEVTGDRSIHRLFVDIVNGKA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: ATPB_CAMFF
Sequence: MKGIISQVMGPVVDVDFKDYLPKINEAIEVNFTVEGNTHKLILETAAHLGDNRVRTIAMDMSEGLTRGLDAIALGSPISVPVGEKVLGRIFNVIGDLIDEGEEEKFDKKWSIHRDPPAFEDQSTKSEIFETGIKVVDLLAPYAKGGKVGLFGGAGVGKTVIIMELIHNVAFKHSGYSVFAGVGERTREGNDLYNEMKESGVLDKVALCYGQMNEPPGARNRIALTGLTMAEYFRDEMGLDVLMFIDNIFRFSQSGSEMSALLGRIPSAVGYQPTLASEMGRLQERITSTKKGSITSVQAVYVPADDLTDPAPATVFAHLDATTVLNRAIAEKGIYPAVDPLDSTSRMLDPQILGEEHYKIARGVQAVLQKYKDLQDIIAILGMDELSEEDKLTVDRARKIEKYLSQPFFVAEVFTGSPGKYVSLEETIAGFKGILEGKYDQLPENAFYMVGNIDEAIAKAEKMRA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZHD3_ORYSJ
Sequence: MDLSGAQGELPLPMHAAASPYLGLHHDHHHHHGGGGGGGGMNGRHMSPPTPPAAAEESKAVVVVSSSATAAARYRECLKNHAAAIGGSATDGCGEFMPGGEEGSLDALRCSACGCHRNFHRKELDAAAAPPLHHHHHQLLGVGAHPRGHGHHHHHLLVAALPPPTRMVMPLSAMHTSESDDAAARPGGGAAARKRFRTKFTAEQKARMLGFAEEVGWRLQKLEDAVVQRFCQEVGVKRRVLKVWMHNNKHTLARRHLHPSPAAAAGDDDDDGAPPPHPDPRRRELAAAAAPPPAPVTQHIKKSVDNKSLISSLAALHCIALLLFHQIDA
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Zinc-finger homeodomain protein 3, OsZHD3.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPS1_CAEBR
Sequence: MVQQLQKSMSDGMATTAAAVPMNANGVDTGKVPTAPPDVFFSTENEPEDCTPVKMDPFDRPKSDKDPVEDAIERLLKVMEKIDCPYTPGKEKGVDQDESDDMTESEDHDEMAKDDEGIPANEVRVETRKMDCTTGQLVAPRIYEKVDTLSSTSESSAEEDESMMIIKEGIRVCYGVWKKRQKNSEMALKGLAIVLELCLTQPSARDEIFSVLLETLGFNTVTYWKAVVPQVVDSDLTYATQYREALLFSMCLYDVNHSKNRLRELYAAIPGFRQSMLGIRAKQFTERYRHLQMKIARSRQSSRMSSKYGSEDNIQAMVTLANDVIMDEETAPTQMPLVDMSHDKQRVINVSNAPPVSISRKTSGSWEIKQGSGGLVACVDPVMSADKKNIWLSNLGVNMQEELKEHSTTTNSIGLPLIKQACAGEVFCVLERNEKKELTPKQQAVESDMSLLSVLNTYNKHSYQLNPVVVNQDDYDTYYGGISNGLLWPALHNLPQFISPCYNDPEALREQWCAYVRVNYLFSINAARNSRAQDFIWIHDYHLMLCGQIMRSLEGSLDVSSIEEREGKQKESLQIGFFLHIPFQPPANFMTKYRTVGEPIVRALLRFTKVGFQTSRDRETFVKLVADHIKRTKIDYDSRLDRYTIEHDGFACSLGVFPVSIKIADFVNIAKNPQTVIEAEEIRKQIMGKCADGGQLFFSVERFDYTKGIAEKLRAWQRYFEKYPDRIGKDVLFQVAVTNRRSVESYRQYQDDVMALAELINQKFHSEQYPEWKPVIFETDGLPRSRLIAHYLAMDIGVVTPSKDGMNLVAKEMLVCNPTASLVLSTGAGTEVQLSNAQFYSEQEGKCYHRVEDIANTEAFADNFFAAATESKETRNKHGEKINQFLCVHDIDEWSDQFLDPKWTHEVISECEVKQLGQFYGLMNRTAQVRRQIVECVLKGLPIRPHFKFSLENAKVTRQANDSECTTLTSLETSCPEGTSKLTLEADEESGEEKGFKITYDIHDELSEMEKDLAFLSFIQSDEYENAEEFIKTIGSFYEGGPILFSEEVKQAAEMLQRGIHYNTFFTDRDGTLKSYACSYPTSVQPAYSAVIQAQFARRCATFCAIVTTAPLIHTGILEVATIPEGYYAYGASAGREWYLNPAQQFKDRSFSAVDLTLMNKVFELIEELLEKPEFRTFKWIGSGIQKHCGHITIAKQDVNGTIPARKVTRLHEQLVKIVNDFDPTGTTLTMRESDLDFKIYVKAKLKGRIFNKGHGIRLVKERLKPNMSKGSCLVCGDSESDIPMLEECLKLAGSKVYTIWVTRDQALQEKVSQLCERYSCTNIHYVTCPQVLLGAMAYATAHTLTNEKNRKADSYYDDSDTPMDQEDTPSKQQ
What is the function of this protein?
Catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a 2 step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1, Trehalose-6-phosphate synthase 1, UDP-glucose-glucosephosphate glucosyltransferase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gob-1 trehalose phosphatase family.
Protein: HDLB_ARCPA
Sequence: MVKYGLFLGCNISFNRPDVEVSMRSIFPALGIELDDLVGQSCCPTWGTMPSVDIVGWCAVAARNLALGEEKGIDLMTACNSCYGSLNEARHKMLTNPEIHRKVNEILATIGKRYEGKAKCRHVAWVLYKDVGLEKLKESIKYTLDGITVAVQPGCHFLWPSEVYPDKEEDPFNPKVLRELCEALGAEAPYYTKLIECCGMGALRSTDPEKSFKLVKEKMENIKEEIDADLIVTTCSSCLIQLDDAQERLRKEGKINFSIPVLHLVQVIALCMGFDPEKVAGICVTPRDEIIKRILENKR
What is the function of this protein?
Has oxidoreductase activity.  The Hdl and Mvh subunits may together mediate electron transfer from hydrogen to an unidentified electron acceptor on the cytoplasmic side of the membrane.
What are the official names of this protein?
Heterodisulfide reductase subunit B-like protein.
What is the protein family that this protein belongs to?
Belongs to the HdrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOU_SERMA
Sequence: MENLNLNKHISGQFNAELENIRTQVLSMGGLVEQQLTDAITAMHNQDSELATRVIEGDSKVNLMEVTIDEACVRIIAKRQPTASDLRLVMAIIKTISELERIGDVADKICRTALEKFSHQHQPLLVSLESLGRHTVQMLHDVLDAFARMDLDEAIRIYREDKKVDKEYEGIVRQLMTHMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYFVKGQDVRHMGGDALEKLLIASDXKKAK
What is the function of this protein?
Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis.  Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB-phoU operon.  PhoU is essential for the repression of the Pho regulon at high phosphate conditions.  In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (By similarity).
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU, Pst system accessory protein PhoU.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX5_ARATH
Sequence: MAMRDLVNGGAACAVPGSSSSSNPLGALTNALLGSSSKTQERLKEIPNANRSGPRPQFYSEDQQIRSLPGSELDQPLLQPGAQGSEFFRGFRSVDQNGLGAAWDEVQQGGPMPPMGPMFEPVQPTFEGPPQRVLSNFLHSFVESSRGGIPFRPAPVPVLGLSQSDKQCIRDRSSIMARHFFADRGEEFINSQVNALLSSLDIDDGIQARGHVPGRFRELDDYWNESQAVVKPNLHPADNWAAEFNQHGMDHGGPDSWVQSFEQQHGVNGWATEFEQGQSQLMSSQMRSMDMQNIAAMEQTRKLAHTLSQDGNPKFQNSRFLQFVSKMSRGELIIDENQVKQASAPGEWATEYEQQYLGPPSWADQFANEKLSHGPEQWADEFASGRGQQETAEDQWVNEFSKLNVDDWIDEFAEGPVGDSSADAWANAYDEFLNEKNAGKQTSGVYVFSDMNPYVGHPEPMKEGQELFRKGLLSEAALALEAEVMKNPENAEGWRLLGVTHAENDDDQQAIAAMMRAQEADPTNLEVLLALGVSHTNELEQATALKYLYGWLRNHPKYGAIAPPELADSLYHADIARLFNEASQLNPEDADVHIVLGVLYNLSREFDRAITSFQTALQLKPNDYSLWNKLGATQANSVQSADAISAYQQALDLKPNYVRAWANMGISYANQGMYKESIPYYVRALAMNPKADNAWQYLRLSLSCASRQDMIEACESRNLDLLQKEFPL
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) (PubMed:17478547, PubMed:19246395, PubMed:20974890).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins (PubMed:11978862, PubMed:15637057).  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle (By similarity).  In addition to promoting peroxisomal translocation of proteins containing a PTS1 peroxisomal targeting signal, mediates peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal via its interaction with PEX7 (PubMed:11978862, PubMed:15548601, PubMed:15637057, PubMed:20130089, PubMed:20974890).  Interaction with PEX7 only takes place when PEX7 is associated with cargo proteins containing a PTS2 peroxisomal targeting signal (By similarity).  PEX7 along with PTS2-containing cargo proteins are then translocated through the PEX13-PEX14 docking complex together with PEX5 (By similarity).  Necessary for the developmental elimination of obsolete peroxisome matrix proteins (PubMed:19246395).
What are the official names of this protein?
Peroxisome biogenesis protein 5, Peroxin-5, AtPEX5, Peroxisomal targeting signal type 1 receptor, Pex5p.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein.
Protein: SPIKE_CVHN1
Sequence: MLLIIFILPTTLAVIGDFNCTNFAINDLNTTVPRISEYVVDVSYGLGTYYILDRVYLNTTILFTGYFPKSGANFRDLSLKGTTYLSTLWYQKPFLSDFNNGIFSRVKNTKLYVNKTLYSEFSTIVIGSVFINNSYTIVVQPHNGVLEITACQYTMCEYPHTICKSKGSSRNESWHFDKSEPLCLFKKNFTYNVSTDWLYFHFYQERGTFYAYYADSGMPTTFLFSLYLGTLLSHYYVLPLTCNAISSNTDNETLQYWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGVYDLSGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSIVLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYAGRVSAAFHQNASSLALLYRNLKCSYVLNNISLTTQPYFDSYLGCVFNADNLTDYSVSSCALRMGSGFCVDYNSPSSSSSRRKRRSISASYRFVTFEPFNVSFVNDSIESVGGLYEIKIPTNFTIVGQEEFIQTNSPKVTIDCSLFVCSNYAACHDLLSEYGTFCDNINSILDEVNGLLDTTQLHVADTLMQGVTLSSNLNTNLHFDVDNINFKSLVGCLGPHCGSSSRSFFEDLLFDKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSESQISGYTTAATVAAMFPPWSAAAGIPFSLNVQYRINGLGVTMDVLNKNQKLIATAFNNALLSIQNGFSATNSALAKIQSVVNSNAQALNSLLQQLFNKFGAISSSLQEILSRLDALEAQVQIDRLINGRLTALNAYVSQQLSDISLVKFGAALAMEKVNECVKSQSPRINFCGNGNHILSLVQNAPYGLLFMHFSYKPISFKTVLVSPGLCISGDVGIAPKQGYFIKHNDHWMFTGSSYYYPEPISDKNVVFMNTCSVNFTKAPLVYLNHSVPKLSDFESELSHWFKNQTSIAPNLTLNLHTINATFLDLYYEMNLIQESIKSLNNSYINLKDIGTYEMYVKWPWYVWLLISFSFIIFLVLLFFICCCTGCGSACFSKCHNCCDEYGGHHDFVIKTSHDD
What is the function of this protein?
Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers are transported to the host plasma membrane, where they may mediate cell- cell fusion.
Protein: ISPD_BACMK
Sequence: MYTLIIPAAGQGKRMGAGKNKLFLLINGVPIIVHTLRAFEKDKACKRIIMAINEEERPYFEELMQKYPVEKQVQFIQGGAERQDSVYNALQYVSGVEYVLVHDGARPFVTNKMMQDVLTAAEKYGASICAVPVKDTIKKVEQGVVVETVERSQLKAVQTPQGFSVPLLLEAHRSAKQSCFLGTDDASLVERVGKKVGVVEGSYYNIKVTTPEDLLIAESFLHVQKK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RIMP_BURM7
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADIDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_CROS5
Sequence: MTQRTLGGTNRKQKRTSGFRARMRKSNGRKVIQARRKKGRHRLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: UBIC_MARN8
Sequence: MPLKDCDQPPELSIPPTFWYRSLVAAGLYCPEVHGPARYWLTVEGSFTRALQQKCQERFHVEILREGFSTPTPEEAKRLNLAPRQLAWVREVRLCGDGRPWVLARTVIPQTCLHGHGRRLRNLGNKPLGAYLFSSPEWQRGPLETGLCKARSNGHPRLARRSLFHRGSCALLVGEYLLPRLYQSPNRG
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH6_MOUSE
Sequence: MRALVSVVSLFFLGIQAHSDWSYSGDDGVGESQWSEQYPSCGGERQSPIDVKTEEVMFNPSLKPLSLVNYEKENLEFTMTNNGHTVSIDLPPSMYLETSDGTEFISKAFHFHWGGRDWELSGSEHTIDGIRSIMEAHFVHFNKEYGTYENAKDQKNGLAVLAVLFKIDEYAENTYYSDIISALKNIEKPGETTTLKDTTIRNLLPKDVHHYYTYPGSLTTPPCTENVQWFVLRDKVTLSKAQVVTIENSVMDHNNNTIQNGYRSTQPNNHRVVEANFLNVQDMYSSYHLYLKNMQKEILQPKKQKKTKKNRHFWSRK
What is the function of this protein?
Reversible hydration of carbon dioxide.  Its role in saliva is unknown.
What are the official names of this protein?
Carbonic anhydrase 6, Carbonate dehydratase VI, Carbonic anhydrase VI, CA-VI, Salivary carbonic anhydrase, Secreted carbonic anhydrase.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_WOLTR
Sequence: MGQKVNPIGFRLKINNNTWDSVWYANKDYKEKLHQDLFIRSYINESFKHAGLSKIIIERKVDLLSVTIHSSRPGVIIGKKGLDIEKVKQKIAEKVKNSVEVNVVGIKRPEIDAALISSSIAQQLEKRVSFRRAMKKAIQSCLRMGGGGIKVGCSGRLGGAEIARTEWYKEGRLPLHTLRANIDYAFCEAKTIYGIIGVKVWVYIVN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: KITH_RAT
Sequence: MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV
What is the function of this protein?
Cell-cycle-regulated enzyme of importance in nucleotide metabolism.  Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate.  Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration.
What are the official names of this protein?
Thymidine kinase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_CAMFF
Sequence: MKKASIISVGAYIPKDILTNFDLEKMVDTSDEWIVKRTGIKTRHLAKNEVTSDLAYKAALMAIQRAGIDKNDIDAVICATITPDYFCMPSTACKVASNLGLFDVTAFDISAACTGFIYLLEIAKSLVESGAKKNVLIIGAEKLSSIINWQDRSTCVLFGDGAGAAIVSSSDDNYIIDVHTSSDGSKGNLLITPGCGIVHPANKDTIDKKLNFLHMSGNEVFKIAVNTLAKDVVDILEKNSVSSKDIDLFIPHQANLRIIEAVKQRLDFTDEQCVVTVVDYGNTSSASIPMAMNDAYEDGRLKQGSLILLDAFGGGFTWGSALLRFGGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_BLOFL
Sequence: MLIIKAILRTEIKKSITRKIRKNGGCPAVIYNKNKSPNINVQLSNKDLSHPENVHYFLKNNKVQILINNEFTITAKIQDVQYHPYKSNIIHIDFIHITTQSRS
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.