PharMolix/UniProtQA huggingface dataset:
Protein: PDLI5_HUMAN
Sequence: MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
What is the function of this protein?
May play an important role in the heart development by scaffolding PKC to the Z-disk region.  May play a role in the regulation of cardiomyocyte expansion.  Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1.  Overexpression promotes the development of heart hypertrophy.  Contributes to the regulation of dendritic spine morphogenesis in neurons.  May be required to restrain postsynaptic growth of excitatory synapses.  Isoform 1, but not isoform 2, expression favors spine thinning and elongation.
What are the official names of this protein?
PDZ and LIM domain protein 5, Enigma homolog, Enigma-like PDZ and LIM domains protein.
What are the subcellular locations of this protein?
Postsynaptic density. Presynapse. Postsynapse. Cytoplasm, cytosol. Note=Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons.
Protein: CIAO1_NEUCR
Sequence: MATETTTATPTAPSATTAEITPLPAFSPDLYQRAWASIPHPSLPLIATCHAHSVTVFSLSTLSKHSVLTGGHTRSVRSAAWQPPRGKVSGKEAKRLRLVTGSFDTTAGVWTWDQGRREESLEREIRLQSGENDQEAEEEEEAEDEWELTLVLEGHENEVKSVNYSPSGQYLATCSRDKSVWIWEDVGNPNPSSEEEDEEEEDEDEWETVAVLQEHDGDVKAVAWCPDVPGRKGKYAPPRRYGDDVLASASYDNTVRLWREDGDGEWVCVAVLEGHEGTVWGVAWEGRPRENDKFPRLLSWGADEVIRVWSLKEPEEEEHGEGAAGGGGNNTWGFGVPNTMRRSLKEEWECTAVLPKVHKGDIYSVAWSTETGLLSSVGSDGVLALYQETANTTEKNEENETNGEAPTTTSAGGWKVLTTVKGAHGPYEINHITWCKRYDAGSERKGEEEMLVTTGDDGVVRPWQVRIQ
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: PIN4_ASPFU
Sequence: MAPKNNAKGGDKKGKGKDASEGDKGKGGGKGLKPATSINVRHILCEKFSKKEEALEKLRNGAKFDDVAREYSEDKARQGGSLGWKVRGSLNADFEKAAYELEPSTTANPKYVEVKTGFGYHIIMVEGRK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase pin4, PPIase pin4, Parvulin-14, Par14.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.
Protein: RL29_NITSB
Sequence: MKYTEIKEKSLQELEGLLKEKKLELFGLRMKLKTMQLQDTSAIRKTRKDIARIKTAIAEKRRAG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS14_SHEAM
Sequence: MAKTSMKAREAKRAALVAKYAEKRAALKAIINSPESSDDARWDAVLKLQALPRDSSAARQRNRCNQTGRPHGFLRKFGLSRIKLREATMRGEVPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SPEH_BACSU
Sequence: METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGDLDPNVAADYIAEALHADTRENIEIPRGMGPVQIKQAQAKVL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: ATPF2_ALBFT
Sequence: MLIDWFTVVAQALNFLILVWLLKRFLYQPILDAIDAREKRIALELADADTKRADAKRERDEFQQKNEVFDQQRAALLGKAMEEAKTERQRLLDDARHAADALATKRQEALRSAQRSMSEALSHRARDEVFAIARKALGDLATTSLEERMGEVFTRRLREMDAKAKAALGEALKTASEPALVRSAFELPADQRAAIQNAINETFSADIPLHFATAPEVVCGIELSTNGQKVGWSITDYLASLEKGVDELLKERDKAEPQSELTRQIRKRAYELYEQQGRKEGRAVQNWDKAESEIRKENLSPAKTEPPPEAKAKPKPEEPKPEIGSP
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ATPG_CAMJE
Sequence: MSNLKEIKRKIKSVHNTQKTTNAMKLVSTAKLKKAEEAAKRSKIYAQKIDEILSEISFQINKIVHNEDDVRLSLFHKKEQIKTVDLIFITADKGLCGGFNIKTLKTVSEMLKEYEAKNINIRLRAIGKTGIEYFNFQKIELLEKYFHLSSSPDYEKACEVIHAAVDDFLNGNTDEVILVHNGYKNMITQELKINHLIPVEPKSIEQTHNSLLELEPEGTELLKDLMKTYFEYNMYYALIDSLAAEHSARMQAMDNATNNAKARVKQLNLAYNKARQESITTELIEIISGVESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS9_BURP1
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIVVNGKPISDYFSRETSLMIVRQPLELTNHAQTFDIKVNVSGGGETGQAGAVRHGITRALIDYDATLKPALSNAGFVTRDAREVERKKVGLHKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YEJL_SALPB
Sequence: MPQLSRYSDEHVEQLLSELLSVLEKHKAPTDLSLMVLGNMVTNLINTSVAPAQRQAIANSFARALQSSISEDNAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: ALKN_ALCBS
Sequence: MKFNSGALFEKLRGGAGEGNTLNIALYVGLAIFIVLALANFLLSATTANKAQENITRASEMRVISQQIAKNALEAAAGNADAFELLDKSQKGFQSAWNAVKDEQVSDPEAMARLQTLWDEVNANADVILKGEDTVLDLHEVADTLAQTIPSLQAEYEGVVEILVTTDAAPEQIAFAQRQSWLAERIVRSIAKVLEGGDGAVIAADSFGRDASLFGRIMNGMIEGDAAMGIDQVNDPDALDYLAEIADLFDEFVNQSVDEILETAPELFQVRNAADTIFRRSQDLLEESTNLNNQFENTTSGLFPSVWLGGVSAGLAVLFFFIIMAQRNRQAAKLKDELESENQRNQAAILRLLDELGDLADGDLTVQATVTEDFTGAIADSINYSIDQLRNLVQTINNSAVQVASAAQETQSTAMHLAEASEHQAQEIAGASAAVNEMAVSIDQVSANAAESAAVAERAVAIANKGAEVVQATIHGMDTIREQIQETSKRIKRLGESSQEIGDIVSLINDIADQTNILALNAAIQASMAGEAGRGFAVVADEVQRLAERSAAATKQIETLVKTIQTDTNEAVISMEATTAEVVKGARLAQDAGVALEEIESVSKTLADLIQNISNAARQQAASAGHISNTMNVIQEITSQTSAGTTATARSIGNLAEMAQDMRNSVAGFRLPEHS
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
What are the official names of this protein?
Putative methyl-accepting chemotaxis AlkN.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DB110_PANTR
Sequence: MKIQLFFFILLFWVTILPAKMKYPEYGSLDLRRECRMGNGRCKNQCHENEIRIAYCIRPGTHCCLQQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 110, Beta-defensin 111, Defensin, beta 110, Defensin, beta 111.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y175_LISIN
Sequence: MEIILKIGILGFGAVFGYLFGEVDLLVKVLVCFIVADYISGLLASGYLGELSSKMGFKGIAKKIAILILVAIAHQIDLILGTHNTTRDAVIFFYLANELISILENFVRMGMKVPEVLKNLILIFDAKSGDEEEKHDKDMD
What are the official names of this protein?
Uncharacterized protein Lin0175.
What is the protein family that this protein belongs to?
Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMN_AQUAE
Sequence: MKAEFDKELIKKYDRPGPRYTSYPPATEFTEEVKEDEYVKRLIKSNERKTPLSLYFHIPFCEQRCLYCGCNVIISHRKGIEEPYLERVCREMDLVSQYLDKDRKVIQLHWGGGTPNYLSPEQIKWFMEEIRKRFEFGDNAEISIELDPRYLTDEQIKAIKDAGFNRISLGVQDLDPKVQQAVNRVQPYELIKEKMEKLREAGFESINLDLIYGLPYQTKESFEKTVEKVIELNPDRIATYSFAYIPQVKPHQQLLPKEALPSAEEKLRIFEMVINKFQEAGYVYIGMDHFAKPEDELAVAQRKGELWRNFQGYTTKKGVELLGFGATSIGMLYDSYFQNWKTLRDYNKTVDEGKIPVFRGYVLNEDDFIRREVIMDIMCNLGVEFSKIENMFGINFREYFAKELEELKEMEEDGLIKVEEDRIKIMPVGRLLIRNVAMVFDAHLRRKKELNFSRTI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRB_SALTY
Sequence: MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNEVTLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQVLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHAGKIEFTSWPGHTEFSVYLPIRK
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC.  In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC.
What are the official names of this protein?
Sensory histidine kinase/phosphatase NtrB, Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_BORRA
Sequence: MDNILRVIILGFVQGISEFLPISSSGHLLLLKKFMNIDLPIVFDIYLHFATVLVVIIYYRRRILELVMVFIKFILRKSKMTELDSSNLNLILLILIITFFTALIGIFIEKFKVLFTFKLVLFNFIVTSILLFLIEFRIKIFNFKKNIFFSGLLIGIMQGIGAMPGISRSGITIFASILLGFSRTKSLEISFLSLIPIVFGSLFLKYNDLFKSDIIFNIFEINLGAIFAFIFGLFSISLFVKMLKNSKLYYFSIYLVSVVSLVYFLV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_SOLM1
Sequence: MTGNIVARRYAKALFALAKKAGKKAPAEYGKDLEAFASVLEGSPDLLKVFANPIISADVKKSVLSGVAGKIGLKPMVINFLSLLADKDRLPCVLEVSALYRTLLDEAEGVMRGQLVTAFALADARQDQIKVKLEKQSGKKLVLSFAVDPSIIGGVVLKVGDKVLDASLRAQLEILKEQIKRGE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ORN_FRAT1
Sequence: MQSADNLIWIDLEMTGLDVDSCKITEIAAIITDKDLNIIAEAEPIAIYQPDEVLANMNEWCIKTHTETGLTQRVKDSKISTEAAEQQILEFIRKFVPYQSSPLCGNSIWQDRRFLAKYMPNIDEYCHYRMLDVTTLKLLNQYWGDGKSFEKKNTHKALDDIRESIAELKFYRQKLLSI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_ALBFT
Sequence: MKYFATICIAAYAGLAGAGGLKSLEVFVKTVNTGRADFTQVVTAPAKAGQAPRVKTSSGTFEFSRPNRFKFVYKKPFEQNIVADGQTLWLYDVDLNQVTARQQSKVLGSTPAALIAAAPDLRALQADFTLADAPDKDGLQWAAATPKSKDGQLQSVRVGFRAGEQAAELAALEILDSFGQRSVLSFSRFEVNPALPGNSFQFKPPAGADVIRQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VHR1_VIOHE
Sequence: GIPCAESCVWIPCTVTALLGCSCSNKVCYN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Root cyclotide 1, Vhr1.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RENT1_DROME
Sequence: MSVDTYAPSSALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQSQTQNDQLEIAQRCSAGDSHPRLASITNDLADLQFEEEDDEPGSSYVKELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGETILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELYNPWSEIGHVIKVPDNFGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSIYDRSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNFGGAGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRAIQQQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYSQHPMPLSLQMTQPSGFALSQQPELSQDFGQISQMDGLLSQDVAFNASGERSLNQFSQPY
What is the function of this protein?
RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD.  The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity).
What are the official names of this protein?
Regulator of nonsense transcripts 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, Cytoplasmic ribonucleoprotein granule.
Protein: Y1417_SYNY3
Sequence: MSQATATQAKGIQLSDAALKHLLALKEQQGKDLCLRVGVRQGGCSGMSYMMDFEEPNRATEHDEVFDYEGFQIICDRKSLLYLYGLMLDYSNALIGGGFQFTNPNANQTCGCGKSFGV
What are the official names of this protein?
Uncharacterized protein slr1417.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family. Ycf83 subfamily.
Protein: FBXL5_MOUSE
Sequence: MAPFPDEVDVFTAPHWRMKQLVGRYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQIENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNQAEERQKVLKYSVDEKADTEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHLYPVHWARGDWYSGPATELDTEPDEEWVRNRKDESRAFQEWDEDADIDESEESAEESVAISIAQMEKRVLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDMALEKISRALGVLTSHQSGFLKSAGKAASTPWTSKDITMPSTTQYACLHNLTDKGIGEEIDNEHSWTEPVSSESLTSPYVWMLDAEDLADIEDAVEWRHRNVESLCVMETASNFGCSSSGCYSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMTTLPATSAMCRKALRTTLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRALTLGGGLPYLEHLNLSGCLTVTGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCGFRACCRSGE
What is the function of this protein?
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2.  Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome.  Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 5, F-box and leucine-rich repeat protein 5.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: PCP_DICDI
Sequence: MSETFIHSVSENQIIVNDLENNNDYDNEDNVFIDSSVYNQECFMEILKKLEDGKPIHEVVRFTSHSSYTHTIVKTIQGLFLYVVLKSVNIYGSYYDFQRYIGPSMMIGTYACPLYRVQYRINKNDSTGAIIKYSNNLDECETYFNHLCKVFNVLTKRLSLNSICCGVGLSDSFYLMNTKTIKKSSRTRISFIIGNSKYSQHRKLDGVINDVNSFYCALLGCSFHSDNIVWLIDSDLRTFYDKWYTFLQLVQSFQSYIEVVVYYAGHGRSDNGNLKLIMTDGNPVQLSIIASTLTESIKNSDSLCLFIVDCCRDGENVLPFHYPIESFDDKKNIAVLFACKYGELSYESLELNAGIFTRSFVKTITERKNNNISTICNLTDIAIKRIYKNYSGCSLIGNFDCSLLEF
What is the function of this protein?
Not required for DIF-induced autophagic cell death and necrotic cell death.
What are the official names of this protein?
Paracaspase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: COX2_PISOC
Sequence: MANWTQLGLQDASSPLMEELIYFHDYTLIILTLITILVFYGLASLIVSSNTNRFFLEGQSLETIWTVIPAVILIFIALPSLQLLYLIDEVNNPFLTIKAIGHQWYWSYEYADYRDLEFDSYMIPTNDLTLGNPRLLEVDNRLTLPSQTPIRVLVTSSDVLHSWTVPSLGIKMDAVPGRLNQVNFFISRCGLFYGQCSEICGANHSFMPIVIESVNFSSFENWVSNFLNE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIMM_AGRFC
Sequence: MAKLENPILMAKIGGAQGLRGEVRVSTYTDDPMALGDYGNLVTADGRVFEILEVREGKNVVVVRFRGINDRNAAESLNGLELFIERDNLPDDELDDDEFYYADLEGLEAVDAEGKSYGAVSAVYDFGAGDLLELKGAGRRPALIPFSEAAVLEIDLEAGRILIDPMAAGLIDNPDDKDQNGMSPFGKK
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1807_METBF
Sequence: MLTDVEGRAAVKLARKTIESFLSEEKLPEPQELGFELSPVFGEKRGVFVTLTESGLLRGCIGHPFPDSRLEDAIMDSAISAATRDPRFPPVREDELNKIVVEVTILTQPEKINAPAEELPERIEVGKHGLIVKQGYCQGLLLPQVAPEYNMDSIEFLGHTCLKAGLLPDAWLKGAEVSCFEGQIFKEKEPCGEVLEENFSCE
What are the official names of this protein?
Protein Mbar_A1807.
Protein: CSRA_ECO55
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: CSA1_CANAL
Sequence: MLPSIVISIVLASFVSAESSITEAPTTTAEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGTSICSVAGVWDPYWMVPANVQSSLSAAATAVASSSEQPVETSSEPAGSSQSVESSQPAETSSSEPAETSSSEPAETSSETSSEQPASSEPAETSSEESSTITSAPSTPEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGTSICSVAGVWDPYWMVPANVQSSLSAAATAVPSSSEQSVETSSESAESSQSVESSQPAETSSEQPSETSSETSSQQLSSITSAPDSSATSSSSTTSTFIRTASINGFADKLYDQLPECAKPCMFQNTGITPCPYWDAGCLCVMPQFAGAIGSCVADSCKGQDIVSVTSLGTSVCSVAGVNAPYWMLPASVKSSLSVAATAVPTSDSASETASQEPSETSSEQPSETASQQPAETSSEESSTITSAPSTPEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGSSICSVAGVWDPYWMLPANVQSSLNAAATAVATSDSASEVASASESASQVPQETSAASSQSANNSVASAAPSNSSVSAAPSSNSSGVPAAPSNNSSGASVVPSQSANNSSASAAPSNNSSSAISESVAPSSYGNSTIAQPSTSTKSDAASITGPITTDKVITNESGIVFTSTVIITHVSEYCDQTSAAAVQSSACEEQSSAKSEQASASSEQVKVITSVVWCESSIQSIESVKTSAEAAHKTEVIASCASELSSLSSAKSEAMKTVSSLVEVQKSAVAKQTSLAAVQSSAASVQLSAAHAQKSSEAVEVAQTAVAEASKAGDEISTEIVNITKTVSSGKETGVSQATVAANTHSVAIANMANTKFASTMSLLVASFVFVGLFI
What is the function of this protein?
Heme-binding protein involved in heme-iron utilization.  The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms.  Required for biofilm formation.
What are the official names of this protein?
Cell wall protein 1, Surface antigen protein 1, Wall protein 1.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.