PharMolix/UniProtQA huggingface dataset:
Protein: RNH_ECOLI
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.  RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer.  Involved in production of retron derived msDNA (a branched RNA linked by a 2',5'-phosphodiester bond to a single-stranded DNA).  Strain K12 / MG1655 does not have retrons, however they can be expressed in this strain which requires this enzyme (tested with retron Ec86) (PubMed:7568472).
What are the official names of this protein?
Ribonuclease HI, RNase HI, Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABG2_DICDI
Sequence: MSDPDVFKILLIGDSAVGKTSLLLRFADNSFQETSVNMTSVDYKNKNIVIDGRTFNLQIWDTAGQERFRTITSSFYRGAHGVLVCYDVTDQLTYNNVRLWMQEIQRYAVLGVSRVLVGNKCDLEDRKLVNTSIAREYADSLGIPFMEASAATGVNVEEAFMAMANEIYRNHMGGSKPSVVNPGSGGTSNTGGKKKFC
What are the official names of this protein?
Ras-related protein RabG2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: WHIA_STRSY
Sequence: MSFTVQVKEELLLQSSQNKSELSAIIKLSGSLGLASSGLTLSISTENAKIARHIYELLLHFYQIKAEIRHHQKPNLKKNRVYAVLIEDGVNEILNDLHLADSFFGLETGISPLVLENDSWSQAYLRGAFLAAGSVKDPEKGKYQLEIASVYSDHANDLANLMQKFLLDAKVIERSKGTITYLQRAEDIMDFLLVIGAEETKTEFENVKLLREARNDLNRATNAEAANIAKTVNASMKTINNIIKIMDTIGLDQLSGDLQEIAQLRIQHPDYSIQQLADSLTVPITKSGVNHRLRKINKIADELTD
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RPP2D_ARATH
Sequence: MATSSSVVSSVPQQHQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKEIEKSRIALAIISQKYTESKWCLNELVKMKELEGKLVTIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLVGFPFNSKSKEKETTLIDKIVDAVLQKLSKISSEESTSGSVDQGRGEEVEEAKADKISGLNQRLKELEEKVAITGDKRDETRIVEVVGMPGIGKSTLLKAFYETWKTRFLSSALLQNISELVKAMGLGRLTGMLLKELLPDENIDEETYEPYKEKLLKNTVFIVLDGISDETHIQKLLKDHRKWAKKGSKIVIARRAVTRDLLHEDSMVRYTYFVPLLSHRDGLNHFCHYAFRHFAAHQNNKEAFMKESKEFVRYARGHPLILKLLGEELREKSLSYWEEKLKSLPKSLSQNIRDRVLQVTYDELSQVQKDAFLDIACFRSHDLVYVKSLLDSSGPAFSKATVTIDALKDMFMIYISDSRVEMHDLLYTFAMELGPEARDDDGRGRHRIWHHHNQDNKGRLNRLLKRPGGSTSVRSFFLDMYVMKTDVTLGTDYLKNMRNLRYLKFYSSHCPQECTPKENIHIPGELELPLEEVRCLHWLNFPKDELPQDFIPKNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALKTLLLGPENMASLVFLNLKGCTGLESLPKINLRSLKTLILSNCSNLEEFWVISETLYTLYLDGTAIKTLPQDMVKLTSLVKLYMKDCEMLVKLPEEFDKLKVLQELVCSGCKRLSSLPDVMKNMQCLQILLLDGTAITKIPHISSLERLCLSRNEKISCLSNDIRLLSQLKWLDLKYCTKLVSIPELPTNLQCLDANGCESLTTVANPLATHLPTEQIHSTFIFTNCDKLDRTAKEVITTYAQRKCQMLSDALKRWNEGFVPEALFSTCFPGCEVPSWFCHEAVGSVLKLNLLPHWNENRFVGIALCAVVGSLPNCQEQTNSCSVTCTFNIASKDSKKGDPYKISFDRLVGRWNKHGNKLDKKGNKLKKTESDHVFICYTRCSNSIKCLQDQHSGTCTPTEAFLEFGVTDKESRLEVLKCGLRLVYASDEPQKTNSDMDLSLSSSDSTPTRNGSSNTTTSSGSVSTNTIREEDSNILHEAQSQNGRGL
What is the function of this protein?
Probable disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At4g19530.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
Protein: RS2_ENT38
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELSKISSRKGKILFVGTKRAASEAVKDAANNCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLEIQSQDGTFDKLTKKEALMRTRELAKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: HUTI_SHESM
Sequence: MSWDQVWIDVNVATMDPSISAPYGAITNAAIAVKDGKIAWLGPRSELPAFDVLSIPVYRGKGGWITPGLIDAHTHLVFAGNRANEFELRLKGATYEEIARAGGGIISTVNACREADEAELFDLGRQRLNALAKEGVTTVEIKSGYGLDTETELKILRVARELGQHHHVDVKTTFLGAHAVPPEFKDNSDGYVDLIINKMLPAVIAENLADAVDVFCENIAFNLEQTERVLSAAKAAGLQVKLHAEQLSNMGGSELAARLGAKSVDHIEYLDEAGVKALSESGTCAVLLPGAFYFLRETQKPPIDLLRQYGVPMVLASDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGLTLNAAKALGIEENVGSLVVGKQADFCLWDIATPAQLAYSYGVNPCKDVVKNGKLVHQ
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_POLAQ
Sequence: MAKAPMRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALTGVMMELEDCAFPLLAGMTAHSDPMTAFKDIDVALLVGARPRGPGMERKDLLSANAQIFTAQGKALNAVAKKTVKVLVVGNPANTNAYIAMKSAPDIPAKNFTAMLRLDHNRALSQLANKLNKPVADIEKLVVWGNHSPTMYPDYRFATIDGKSVKDSINDAAWNKDVFIPTVGKRGAAIIEARGLSSAASAANAAIDHIHDWVLGTNGKWVTMGIPSKGEYGIPAEVIYGFPVTCENGEYKMIEGLEIDEFSRERMTHTLNELLEEQAGVKHLLP
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: FLGH_BRUA2
Sequence: MNKAILAVAMVLLLAGCATKPEEIGRAPDLSPVAAHLGMQNNPQFNGYPARPGKASYSLWDQRSTNFFKDPRAATPGDVLTVIISINDRANLDNKTDRERVSKGIYGGGGSFATSSITGAAAGGDMDASVNTHSDSKSKGKGTIERSEDIRLQIAAIVTDTLPNGNLIIRGSQEVRVNNELRVLNVAGVVRPRDISGNNTISYDKIAEARISYGGRGRLSEIQQPPYGQQILDQFSPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PGP_METS5
Sequence: MIKLLLTDLDGTLTEDRGTYVVDIGAIKALRRAEKAGIRVALVSGNSYPVLRGLHNYLGLSGGLVAENGCFVFHGGVTFRVCETVPREVVSEFAKTFNLRESWQNEFRRSDFGFTPAELKDEMIKWAEERGLVVQSSGYALHLSGKPGGKGAGVRKLLELANVKREETGAIGDSRTDIEMFREAGITAAVSNADPELKRVASISLKLKSGAGVMEFIDMLLS
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: DTL_DANRE
Sequence: MTLFHHVVDRGAKKRGRNGEQRLFPLSSLLDGYECARRDEHISYGASAAAVPPFGCTFSSAHGQQNCLAVANEEGFVTIFNTGEKQSSVLKEWQAHDNAVFDIAWVPGTNCLVTASGDQTARLWDVITGDLLGTFKGHQCSLKSVAFYKQEKAVFSTGGRDGNIMIWDTRCSKKDGFYRQVKQISGAHMKPERFTPQTKKRRGMAPPVDSQQGVTVVLFCDETKLISSGAVDGIIKMWDLRRNYTAYHQNPLPLQAYPYPGSCTRKLGYSGLSLDYTGSRLFSNCTDDNIYMFNISGLKTTPVAVFSGHSNSSFYVKSTVSPDDQFLASGSSDHNVYIWKISDPKQAPMMLQGHSQEVTSVAWCPTDFTKIASCSDDNTVRIWRLNRKPEGENSTIQDGNLVGWTIRKVQSPNRTPGHHSPVELTPSKNPGSVRSVSLASPQPATCAPTGAALPLPSNTSSAPPAKLTSPKMPSSLQQWISRSSKSPVRKALTPVLQGLSFEHRVKRRLETGDSASSGLGEEIDGVSELYPNVKRSRSSVSTLKKEDSFGLESEKRLGSDGAEASGKENSSPRRTDWLSVISQKFKGSAQPKSPSSGSSQQDTRTLESPAAVSPRPMKVFSPPTNKKASPSKPMKKISSYFMKRTQD
What is the function of this protein?
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis.  The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2.  CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication.  CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing.  KMT5A degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration.  Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation.  In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (By similarity).  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Denticleless protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat cdt2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
Protein: RL16_PETMO
Sequence: MLMPKRVKYRKQQRGTVRGMTKGASLVHFGDWGLKAMESSWITAQQIEACRLSMVRTLKRTGNIWINIFPDKPITSKGIGTRQGKGKGDVEGWVAVVKKGRVMFEIGGVDEATAKRALEYAASKLPIRTKIVQRYEIGGEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: XERC_SERMA
Sequence: MTPIAPSLQQPVDAFLRYLKVERQLSPLTQLSYSRQLTALMRLAQEIGVTDWTTLDAARVRMLAARSKRAGLQSASLALRLSSLRSFLDWLVSQGVLHANPAKGIRTPRSGRHLPKNIDVDEMNQLLEIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDCRHVDMAAGEVWVMGKGSKERKLPIGRTAVTWLEHWLAMRDLFGPQDDAMFLSNQGRRISTRNVQKRFAEWGVKQGVNSHIHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKRGKS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_ECOL5
Sequence: MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_LIMRJ
Sequence: MSLDKKTVADRYAKALFELVDADNELDQTYQELIALRQVFEDNEGLDAALAGVQLSLDEKKSLIKDLQQGASKYVANLIQMVFDYGRIDCMVAIIDEFERRYDRKMKRMHADVTTAIQLDKQQEDQLKANLAKRFGANEVTLTKHVDPEILGGVIVHVDNKTLDGSLSSKIKQIRRLLVR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KUP2_LACLM
Sequence: MGQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAVSLVIWTLTLITTVKYVLIALKADNHHEGGIFSLFTLVRRMRKWLIVPAMIGGATLLADGALTPAVTVTSAIEGLRGVTHVYSNQTTVMVTTLIILAFLFLIQRFGASLVGRLFGPIMFIWFGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDLGHVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILSTLAAIIASQALISGSFTLVSEAIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFVLYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKIAIAFISIGLFCIEGSFFAASLVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLYQTNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDFIVRVNLYLGFRMRQEVPRYLRTIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKLMNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTVETVPLVLSDVRNLEIHERLEQVDETEAPATN
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSRP_STAHJ
Sequence: MAKKKTKSPGTLAENRKARHDYNIEDTIEAGIALKGTEIKSIRRGSANLKDSYAQVKRGEMFINNMHIAPYEEGNRFNHDPLRSRKLLLHKKEIIKLGERTREIGYSLIPLKLYLKHGQCKVLLGVARGKKIHDKRQALKDKAMKRDVDRAIKDRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: UIF_XENTR
Sequence: MAPLKTSVPDTMDKIDMLLDDIIKLNKQEQNRNQLKGRYNGSFRQFRNSWGRWGAQRTSGAGNTLRSQGLKKRTYGVKTGLAMRKMASWKGTSPLNRPPLSVRNSPGQLVSFRKRMNLQRSPDFGVKTSSSLQRYYLRSSSYAQTNTFRSGFRMDQQRETRQATFLSRRGLKVQTLMDMDQHLDLPELSRTPPWRTSVSSGGTLTVSIDNPSAVTSSSSLGSRLPRPPFPFLTKKEGSETKVPKGVPLEFDINSVAKQTGITLNERFKILKEQRLAQAFTKGNRFVTVG
What is the function of this protein?
Required for mRNA export from the nucleus to the cytoplasm.  Acts as an adapter that uses the ddx39b/uap56-nfx1 pathway to ensure efficient mRNA export and delivering to the nuclear pore (By similarity).
What are the official names of this protein?
UAP56-interacting factor, Forty-two-three domain-containing protein 1, Protein 40-2-3.
What is the protein family that this protein belongs to?
Belongs to the UIF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle.
Protein: SCAF_BPT3
Sequence: MAESNADVYASFGVNNAVMTGSTPTEHEQNMLSLDVAARDGDDAIVLSDEPTSHNDDPYAAGVDPFADGEDDEGRIQVRISEDGNEAGFDTDGDNSEVETEGEDVEFEPLGDTPEELSQVTEQLGQHEEGFQAMVEQAVERGLSADSVSRIYEEYEADGISEKSYAELEAAGYSRAFVDSYISGQEALVDQYVNQVVAFAGGQERFSAIHTHLEATNPAAAESLESAMMNRDLATVKAIINLAGESYTKKFGKPANRSVTKRATPVKPVARQKEGFTNQAEMIKAMSDPRYRSDSAYRQMVEQKVIDSSF
What is the function of this protein?
Scaffolding protein involved in the icosahedric procapsid assembly.  Coassembles with the capsid proteins to form the procapsid, in which the scaffolding protein is found within the external shell of icosahedrally arranged capsid protein subunits.  In a subsequent step the scaffolding protein molecules are released from the procapsid.  Facilitates assembly by binding to gp10 hexamers but not the pentamers and locking them into a morphogenically correct conformation.
What are the official names of this protein?
Capsid assembly scaffolding protein, Capsid assembly protein, Gene product 9, Gp9, Head morphogenesis protein, Scaffold protein, Scaffolding protein.
What is the protein family that this protein belongs to?
Belongs to the T7likevirus capsid assembly scaffolding protein family.
Protein: YUTH_BACSU
Sequence: MVKGTIKEKYGIHIRQLSMYQHTYQCFQTPNSYFLIVPVSQFSETELAELYYMSQYLQEQSDPYVSVFIFTKEGELTFEHEGKTYALLKAAPPYSNRAFSIGAELAEFHRKGRGYPYEVKAAGRIGQWKDLWGKRIDQLEAFWQRKVQTPPHEPFDKKMIESFPYYLGLSENAIQYLVDTELDDKPQAADSGTICHQRMERHTWSPESLIRIPADWVFDHASRDLAEYMRHTFLHHRQDFNQQGFLFLQEYEQVTPLSSFSKRLLYSRLLFPLHYFEIVESYYMSSESEKHYFEEQLDFILNDCGRYEQFLNTAQEFMNMRAQKLFVPRVSWLGKGSSR
What is the function of this protein?
Involved in sporulation.
What are the official names of this protein?
Endospore coat-associated protein YutH.
What is the protein family that this protein belongs to?
Belongs to the CotS family.
What are the subcellular locations of this protein?
Forespore outer membrane; Peripheral membrane protein. Spore coat. Note=Initially localizes to a focus at one end of the forespore, which then undergoes transformation into a ring adjacent to the forespore. Next, the ring becomes a cap at the mother cell pole of the forespore that eventually spreads around the entire developing spore.
Protein: CLPX_BACC1
Sequence: MFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CCA_HYDCU
Sequence: MKTYLVGGAVRDALLNIPVYDHDWVVVGATPQDMLEQGFSQVGKDFPVFLHPKTKEEYALARTERKSGQGYHGFEVSFDPTVTLEDDLIRRDLTINAMAQDAEGQIVDPYGGQQDLADKVLRHVSEAFAEDPLRVLRVARFAAKLSAFGFTLAPETAALMKSMSASGELSALTPERVWQEVVKALNTQTPSVFFEVLDHVNALSILFPALDALKGVQQPEKHHPEGDAWVHTMMVLDASAALSNDVSVRFAALVHDLGKGLTPKALWPKHHGHEKAGVPLVAALCQQYRVPKKIQIFAEKVTEYHGLIHRGLDLEGHPHLKTATFLKVLSACQAFKEVAQFESLLIACEADAKGRLGFESRPYPQKDFWLELAKRANAVDNQAILATGVKGAEIGEAIVQERMRLIEDFVREYSAI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MU180_SCHPO
Sequence: MISLSLLYRILTLPIILVGTTILYFTIGTNFPHDELRHNLLSTLFCSSMLHLSKGLTVKDVRIFFHDSIGSTLLKNRKKLNSENELPNYGEKFTHKYDNQDMPDSVWLAKVNGMTKSDPIILHLHGGMMALPYDKVILVGLSNLYKLFSTTMNRPPSILLVDYSLVSQGYTYPKQVRECLNVYQVLISKGFRNITVLGESAGGTLILSFLYQISELSKLNKVVWPKGVALISPWLDLTNAKKIGSYRANDGLDVICYETLNRFGKAYVNNEESLFTSSVVNINMNCDISIWSKIPPIQDGKVLVLFGENEVFRDEILSWTSKIGLLKAYPNRVLMDKQGIHIGLFLEESPSIGPGMTNLDIWKKKFSVNSLYTFLRETFEE
What is the function of this protein?
Required for the deacetylation of acetylated sterols (By similarity).  Has a role in meiosis.
What are the official names of this protein?
Putative steryl acetyl hydrolase mug81, Meiotically up-regulated gene 180 protein.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Single- pass type II membrane protein.
Protein: RECF_SHESW
Sequence: MSLTRLNIEAFRNIQFAQLIPAPGINVIYGQNGSGKTSILEAIYFLGMGRSFRSHLSQRVINNDNDKLTLFATLNLARGDSKIGLRRFRSGETEVKIDGEKVKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHADPQFYGAWTNVRRVLKQRNQLLRNGAVYTHIQFWDQEFVRYAEQVTEIRNHYVDSLNGLLKGIIGEFLPSVDVKVSFTRGWDSKTDFAELLENQYSRDLATGHTVSGPHKADLRLRVGNLPAQDALSRGQLKLLVCALRIAQGKLLKQQIDKHSIYLVDDLPSELDAQHRQLLLKQLTDTGAQVFVTAIDPAAIVDSLHTPPNRMFHVEQGRVTVVE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR5_RABIT
Sequence: MDYSMSTALYDIDYGMSEPCQKIDVKQVAARLLPPLYSLVFIFGFVGNLLVVLILITCKKLKSMTDIYLLNLAISDLLFLLTLPLWAHYAAAEWDFGGAMCKVFTGMYHMGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSGVTWVAAILVSLPDIIFTRSQKEGFRCSCSPHFPASQYQFWKNFHTIMRNILSLVLPLLVMIVCYSGILKTLLRCRNEKRRHRAVRLIFAIMVVYFLFWAPYNVVLLLNTFQEFFGLNNCSSSNRLDRAMQVTETLGMTHCCINPVVYAFVGEKFRSYLSAFFRKHVAKRLCKHCPLLPRETPEPASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, MIP-1 alpha receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_BURA4
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.